# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- RRM_1 PF00076.22 EGO51326.1 - 1.4e-13 50.5 0.0 1.9e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGO51326.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.27 EGO51327.1 - 5.5e-50 169.4 0.1 1.7e-26 93.4 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGO51327.1 - 7.6e-16 58.8 5.0 0.00026 20.9 0.0 4.4 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGO51327.1 - 3.3e-13 49.6 0.8 0.0018 17.8 0.1 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain Chromo PF00385.24 EGO51327.1 - 3.2e-11 43.0 0.0 6.5e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 EGO51327.1 - 6.7e-11 43.1 1.8 1e-05 26.2 0.1 2.6 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 EGO51327.1 - 4.7e-08 32.7 0.7 0.0044 16.7 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGO51327.1 - 2.3e-07 30.9 0.0 0.0032 17.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO51327.1 - 1.4e-06 28.3 0.1 0.023 14.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 EGO51327.1 - 2e-05 25.2 0.1 0.11 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EGO51327.1 - 3.3e-05 24.2 0.0 0.0056 16.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EGO51327.1 - 3.5e-05 23.7 0.3 0.23 11.1 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGO51327.1 - 8.6e-05 22.8 0.1 0.65 10.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGO51327.1 - 0.00095 19.5 0.1 2.7 8.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase SbcCD_C PF13558.6 EGO51327.1 - 0.0016 18.6 0.0 0.67 10.2 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MeaB PF03308.16 EGO51327.1 - 0.0016 17.5 0.3 1.3 7.9 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EGO51327.1 - 0.0022 18.2 0.0 2.9 8.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EGO51327.1 - 0.0047 17.0 2.4 0.42 10.7 0.1 3.3 3 0 0 3 3 3 1 Helicase HerA, central domain AAA PF00004.29 EGO51327.1 - 0.0049 17.3 0.1 5.9 7.3 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGO51327.1 - 0.0051 16.5 0.6 3.5 7.3 0.1 3.0 2 0 0 2 2 2 1 AAA domain DUF3584 PF12128.8 EGO51327.1 - 0.0059 14.2 0.5 0.15 9.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) NACHT PF05729.12 EGO51327.1 - 0.0062 16.5 0.3 2.2 8.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.23 EGO51327.1 - 0.0065 16.5 0.1 0.9 9.6 0.0 3.1 2 1 0 2 2 2 1 Dynamin family AAA_27 PF13514.6 EGO51327.1 - 0.0082 15.8 0.0 4.2 6.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 EGO51327.1 - 0.014 14.1 0.0 1.5 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EGO51327.1 - 0.014 15.2 0.1 0.99 9.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 EGO51327.1 - 0.015 14.4 0.1 3.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) HEAT_2 PF13646.6 EGO51327.1 - 0.024 15.0 4.2 0.36 11.2 0.0 3.8 2 2 0 3 3 3 0 HEAT repeats AAA_24 PF13479.6 EGO51327.1 - 0.027 14.2 1.9 0.64 9.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGO51327.1 - 0.033 14.6 0.0 1.6 9.1 0.0 2.8 3 0 0 3 3 2 0 AAA ATPase domain HEAT PF02985.22 EGO51327.1 - 0.048 13.9 0.4 1.1e+02 3.5 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat Roc PF08477.13 EGO51327.1 - 0.064 13.5 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 EGO51327.1 - 0.064 12.4 0.1 4.1 6.5 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 EGO51327.1 - 0.068 13.2 0.0 10 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 EGO51327.1 - 0.11 12.3 0.1 7.4 6.3 0.0 2.6 2 0 0 2 2 2 0 MukB N-terminal Alginate_exp PF13372.6 EGO51327.1 - 0.13 10.9 0.1 0.21 10.3 0.1 1.1 1 0 0 1 1 1 0 Alginate export TsaE PF02367.17 EGO51327.1 - 0.17 11.9 0.9 19 5.3 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 EGO51327.1 - 0.18 11.4 0.7 27 4.3 0.1 3.3 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain ALF PF03752.13 EGO51327.1 - 0.24 11.4 1.5 11 6.1 0.3 3.0 2 0 0 2 2 2 0 Short repeats of unknown function NTPase_1 PF03266.15 EGO51327.1 - 1.3 8.9 5.2 14 5.5 0.2 3.1 3 1 0 3 3 2 0 NTPase Glyco_hydro_16 PF00722.21 EGO51329.1 - 9.5e-16 57.8 0.1 1.5e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Arrestin_N PF00339.29 EGO51329.1 - 0.017 15.2 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Glyco_trans_2_3 PF13632.6 EGO51330.1 - 6.7e-51 173.0 2.6 2.2e-50 171.3 2.5 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGO51330.1 - 5.1e-06 26.4 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGO51330.1 - 0.0062 16.0 0.1 0.021 14.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Flavi_NS2A PF01005.19 EGO51330.1 - 0.019 15.1 0.3 0.048 13.8 0.1 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS2A Glyco_tranf_2_3 PF13641.6 EGO51330.1 - 0.048 13.6 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Sox_N PF12444.8 EGO51332.1 - 0.32 12.2 3.4 5.6 8.2 1.1 2.3 2 0 0 2 2 2 0 Sox developmental protein N terminal SSF PF00474.17 EGO51333.1 - 2.7e-21 75.9 29.4 3.4e-21 75.6 28.8 1.5 1 1 0 1 1 1 1 Sodium:solute symporter family HET PF06985.11 EGO51334.1 - 8.2e-25 87.9 0.0 1.6e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Formyl_trans_N PF00551.19 EGO51335.1 - 2.5e-37 128.4 0.1 3.1e-37 128.1 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 EGO51335.1 - 1.1e-08 34.7 0.0 3.2e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 EGO51335.1 - 0.00027 20.8 0.3 0.0016 18.4 0.0 2.3 2 1 1 3 3 3 1 ACT domain ZnuA PF01297.17 EGO51335.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic MFS_1 PF07690.16 EGO51336.1 - 4.7e-34 117.9 18.7 8.6e-34 117.0 18.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO51336.1 - 9.7e-13 47.8 7.6 1e-11 44.4 7.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 EGO51336.1 - 9.6e-06 24.3 0.4 9.6e-06 24.3 0.4 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_2 PF13347.6 EGO51336.1 - 0.00012 20.8 14.0 0.021 13.4 2.1 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 EGO51336.1 - 0.00032 19.3 1.8 0.00052 18.6 1.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EGO51336.1 - 0.0029 16.9 3.7 0.0029 16.9 3.7 2.9 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB BT1 PF03092.16 EGO51336.1 - 0.0035 15.6 0.0 0.34 9.1 0.0 2.3 1 1 1 2 2 2 2 BT1 family MFS_1_like PF12832.7 EGO51336.1 - 0.05 12.5 5.4 2.7 6.8 5.4 2.9 1 1 0 1 1 1 0 MFS_1 like family OATP PF03137.20 EGO51336.1 - 0.058 11.7 3.3 2 6.6 0.2 2.7 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Folate_carrier PF01770.18 EGO51336.1 - 0.092 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier MRJP PF03022.16 EGO51337.1 - 4.9e-28 98.3 0.0 2.4e-27 96.1 0.0 1.9 1 1 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 EGO51337.1 - 0.00018 21.2 0.0 0.00038 20.1 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Acetyltransf_1 PF00583.25 EGO51338.1 - 1.1e-09 38.6 0.0 1.7e-09 37.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO51338.1 - 1.5e-08 34.7 0.0 2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO51338.1 - 4.8e-07 30.1 0.0 8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGO51338.1 - 2.2e-05 24.5 0.0 0.028 14.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGO51338.1 - 0.026 14.7 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Fungal_trans PF04082.18 EGO51339.1 - 7.4e-05 21.9 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO51339.1 - 5.1 7.3 22.8 0.046 13.9 11.3 2.6 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ARL2_Bind_BART PF11527.8 EGO51340.1 - 0.17 12.0 3.6 0.18 11.9 3.6 1.3 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART Zn_clus PF00172.18 EGO51341.1 - 6.8e-06 26.1 13.1 1.1e-05 25.5 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 EGO51341.1 - 5.6 7.1 16.3 0.42 10.7 1.9 4.1 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 FAD_binding_3 PF01494.19 EGO51342.1 - 1.4e-07 31.1 0.6 0.0026 17.1 0.2 2.6 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 EGO51342.1 - 3.8e-06 26.7 0.1 5.7e-05 22.9 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO51342.1 - 0.00021 21.5 1.4 0.0003 20.9 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO51342.1 - 0.0032 16.8 0.0 0.013 14.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase CDI PF02234.19 EGO51342.1 - 2.5 8.4 7.3 1 9.6 0.1 2.7 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor Chitin_bind_1 PF00187.19 EGO51343.1 - 1.3e-15 57.5 68.0 4.3e-07 30.3 15.7 4.3 3 2 0 3 3 3 3 Chitin recognition protein AJAP1_PANP_C PF15298.6 EGO51343.1 - 0.081 13.1 17.6 1.1 9.5 3.0 2.2 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Mucin PF01456.17 EGO51343.1 - 0.11 12.5 29.4 0.11 12.5 8.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Transferase PF02458.15 EGO51344.1 - 3.2e-22 78.8 0.0 1.8e-20 73.0 0.0 2.9 1 1 0 1 1 1 1 Transferase family MIP PF00230.20 EGO51345.1 - 1.1e-46 159.5 19.7 1.4e-46 159.0 19.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF1201 PF06716.11 EGO51345.1 - 1.6 8.8 7.1 0.89 9.6 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) Cofilin_ADF PF00241.20 EGO51346.1 - 9.1e-22 77.1 0.0 1e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Glyco_hydro_3_C PF01915.22 EGO51347.1 - 3.8e-47 160.9 0.0 8.9e-47 159.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO51347.1 - 3.6e-44 151.4 0.0 7e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGO51347.1 - 1e-21 76.8 0.1 3.1e-21 75.2 0.1 1.9 1 0 0 1 1 1 1 Fibronectin type III-like domain bZIP_2 PF07716.15 EGO51347.1 - 2.3e-07 30.8 9.7 4.4e-07 29.9 9.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EGO51347.1 - 1.4e-06 28.2 6.5 3e-06 27.2 6.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EGO51347.1 - 0.082 13.4 2.0 0.18 12.4 2.0 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Takusan PF04822.13 EGO51347.1 - 0.93 9.4 3.8 1.9 8.4 3.8 1.4 1 0 0 1 1 1 0 Takusan ABC2_membrane PF01061.24 EGO51348.1 - 1.9e-78 262.7 42.0 2.4e-42 144.7 10.4 2.8 4 0 0 4 4 2 2 ABC-2 type transporter PDR_CDR PF06422.12 EGO51348.1 - 6.5e-34 115.7 1.2 8.7e-26 89.7 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 EGO51348.1 - 2.9e-26 92.6 0.2 1.6e-16 61.1 0.1 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGO51348.1 - 8.1e-05 22.6 0.2 0.067 13.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EGO51348.1 - 0.00023 21.7 0.0 0.00049 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGO51348.1 - 0.00033 20.6 0.1 0.00066 19.6 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EGO51348.1 - 0.0007 20.0 0.1 0.0018 18.7 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_trans_N PF14510.6 EGO51348.1 - 0.002 18.7 1.1 0.007 17.0 1.1 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_28 PF13521.6 EGO51348.1 - 0.0022 18.3 0.0 0.0052 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO51348.1 - 0.0076 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EGO51348.1 - 0.013 15.6 0.0 0.037 14.1 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 EGO51348.1 - 0.013 15.0 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EGO51348.1 - 0.03 14.6 0.0 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGO51348.1 - 0.032 13.8 0.0 0.088 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EGO51348.1 - 0.048 13.1 0.0 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 EGO51348.1 - 0.075 12.7 0.2 0.35 10.5 0.1 2.2 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 EGO51348.1 - 0.14 12.0 0.1 0.36 10.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain UPF0542 PF15086.6 EGO51348.1 - 0.24 11.4 0.7 0.91 9.5 0.7 2.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 ABC2_membrane_3 PF12698.7 EGO51348.1 - 1.4 7.9 34.7 0.03 13.4 8.9 2.9 2 1 0 2 2 2 0 ABC-2 family transporter protein adh_short_C2 PF13561.6 EGO51349.1 - 6.1e-36 124.1 0.1 1.6e-35 122.7 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO51349.1 - 7.2e-36 123.5 0.0 1.3e-35 122.7 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO51349.1 - 1.9e-09 37.7 0.0 3.3e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 EGO51349.1 - 0.025 13.9 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RDM PF11002.8 EGO51349.1 - 0.047 13.7 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 RFPL defining motif (RDM) 3HCDH_N PF02737.18 EGO51350.1 - 6.3e-27 94.6 0.0 9.5e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EGO51350.1 - 3.3e-10 40.5 0.0 6.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ldl_recept_b PF00058.17 EGO51350.1 - 1.7e-07 31.6 0.0 0.049 14.1 0.0 5.1 5 0 0 5 5 5 2 Low-density lipoprotein receptor repeat class B PQQ PF01011.21 EGO51350.1 - 0.0033 17.3 0.0 0.0088 15.9 0.0 1.7 1 0 0 1 1 1 1 PQQ enzyme repeat Arylesterase PF01731.20 EGO51350.1 - 0.0035 17.5 0.0 0.36 11.1 0.0 3.2 3 0 0 3 3 3 1 Arylesterase SGL PF08450.12 EGO51350.1 - 0.0046 16.6 0.0 1.5 8.3 0.0 3.0 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region NAD_Gly3P_dh_N PF01210.23 EGO51350.1 - 0.099 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Str_synth PF03088.16 EGO51350.1 - 0.1 12.7 0.0 33 4.7 0.0 3.1 2 1 0 2 2 2 0 Strictosidine synthase FAD_binding_6 PF00970.24 EGO51351.1 - 1.9e-31 108.3 0.0 3.5e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGO51351.1 - 1.9e-31 108.9 0.0 5.7e-31 107.4 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 EGO51351.1 - 9.9e-22 76.9 0.1 1.9e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EGO51351.1 - 0.0014 18.8 0.0 0.011 15.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EGO51351.1 - 0.13 12.5 0.1 0.66 10.2 0.0 2.3 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain LAL_C2 PF18603.1 EGO51352.1 - 0.14 12.3 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 p450 PF00067.22 EGO51353.1 - 3.6e-66 223.8 0.0 4.3e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 EGO51354.1 - 8.8e-07 29.0 9.5 1.9e-06 27.9 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain C2 PF00168.30 EGO51355.1 - 2.7e-28 98.3 0.0 1.1e-15 57.8 0.0 2.7 2 0 0 2 2 2 2 C2 domain VIT1 PF01988.19 EGO51355.1 - 0.082 12.8 0.1 18 5.1 0.2 2.5 2 0 0 2 2 2 0 VIT family SIMPL PF04402.14 EGO51356.1 - 0.015 15.8 0.1 0.03 14.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Aa_trans PF01490.18 EGO51357.1 - 7.6e-91 304.8 13.3 1e-90 304.4 13.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EGO51357.1 - 6.5e-05 22.1 17.6 0.00013 21.2 17.6 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Dynactin_p22 PF07426.11 EGO51358.1 - 3.2e-05 23.8 0.0 8e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Dynactin subunit p22 PKcGMP_CC PF16808.5 EGO51358.1 - 0.45 10.4 3.8 0.64 9.9 0.4 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SH3_1 PF00018.28 EGO51359.1 - 2.3e-08 33.5 0.1 3.7e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGO51359.1 - 8.2e-07 28.6 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGO51359.1 - 5.6e-06 26.1 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DASH_Spc19 PF08287.11 EGO51360.1 - 5.4e-47 159.6 0.1 7.1e-47 159.2 0.1 1.2 1 0 0 1 1 1 1 Spc19 TackOD1 PF18551.1 EGO51362.1 - 0.036 13.7 1.4 0.048 13.3 1.4 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 YjeF_N PF03853.15 EGO51363.1 - 9.3e-34 116.8 0.0 1.1e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus DprA_WH PF17782.1 EGO51363.1 - 0.055 13.6 0.2 0.16 12.1 0.2 1.8 1 0 0 1 1 1 0 DprA winged helix domain Ribosomal_S16 PF00886.19 EGO51364.1 - 1.1e-26 92.6 0.3 2.5e-26 91.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S16 Glyco_hydro_16 PF00722.21 EGO51366.1 - 1.9e-44 151.2 2.3 3.6e-44 150.3 2.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Mid2 PF04478.12 EGO51366.1 - 0.037 13.9 0.1 0.067 13.0 0.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM51 PF15345.6 EGO51366.1 - 0.04 13.8 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 NPV_P10 PF05531.12 EGO51367.1 - 0.11 13.0 0.6 0.11 13.0 0.6 6.0 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 EGO51367.1 - 0.12 12.4 33.3 0.29 11.2 3.1 3.6 1 1 1 3 3 3 0 Laminin Domain II DUF717 PF05338.12 EGO51367.1 - 0.43 10.7 3.5 3.1 8.0 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF717) Spc7 PF08317.11 EGO51367.1 - 1.3 7.9 47.8 0.28 10.0 7.7 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein She9_MDM33 PF05546.11 EGO51367.1 - 4.1 7.2 26.1 7.6 6.3 17.5 3.2 2 1 1 3 3 3 0 She9 / Mdm33 family Fib_alpha PF08702.10 EGO51367.1 - 4.4 7.5 37.0 7 6.8 4.4 4.2 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 EGO51367.1 - 8.5 6.8 34.3 13 6.1 0.1 5.8 1 1 5 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GrpE PF01025.19 EGO51368.1 - 0.0064 16.2 7.3 0.058 13.0 0.8 2.1 1 1 1 2 2 2 2 GrpE DUF1664 PF07889.12 EGO51368.1 - 0.014 15.4 0.7 0.09 12.8 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.8 EGO51368.1 - 0.018 15.1 3.2 0.018 15.1 3.2 1.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HSCB_C PF07743.13 EGO51368.1 - 0.029 14.8 3.8 0.4 11.2 0.2 2.3 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF4407 PF14362.6 EGO51368.1 - 0.03 13.7 1.6 0.046 13.1 1.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 EGO51368.1 - 0.057 13.2 3.3 0.077 12.8 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) BRE1 PF08647.11 EGO51368.1 - 0.074 13.1 0.4 0.074 13.1 0.4 2.3 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 EGO51368.1 - 0.13 12.8 8.8 0.15 12.6 1.6 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Sec2p PF06428.11 EGO51368.1 - 0.19 11.7 8.2 0.045 13.7 1.8 2.2 1 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p bZIP_1 PF00170.21 EGO51368.1 - 0.62 10.2 7.0 0.3 11.2 0.5 2.6 2 2 0 2 2 2 0 bZIP transcription factor TMF_DNA_bd PF12329.8 EGO51368.1 - 0.7 9.9 10.1 0.66 10.0 1.2 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cep57_CLD_2 PF14197.6 EGO51368.1 - 0.77 9.9 8.2 0.074 13.2 3.0 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 SlyX PF04102.12 EGO51368.1 - 0.85 10.3 4.2 1.1 9.9 0.8 2.2 2 1 0 2 2 2 0 SlyX bZIP_2 PF07716.15 EGO51368.1 - 0.97 9.6 6.5 0.98 9.6 1.4 2.7 2 1 0 2 2 2 0 Basic region leucine zipper KxDL PF10241.9 EGO51368.1 - 1.4 9.3 5.7 3.8 7.8 0.5 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein TolA_bind_tri PF16331.5 EGO51368.1 - 1.7 8.8 7.7 0.38 10.8 3.0 2.1 2 1 0 2 2 2 0 TolA binding protein trimerisation Amidase PF01425.21 EGO51369.1 - 0.011 14.7 0.0 0.029 13.3 0.0 1.7 1 0 0 1 1 1 0 Amidase MAGE_N PF12440.8 EGO51369.1 - 5.2 7.8 9.3 1.2 9.9 4.7 2.4 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal TPR_2 PF07719.17 EGO51370.1 - 3.3e-07 29.9 8.8 0.5 10.6 0.0 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO51370.1 - 7.6e-05 22.6 0.0 1.3 9.4 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO51370.1 - 0.00011 21.9 1.4 1.5 9.0 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO51370.1 - 0.00033 21.1 8.4 0.019 15.5 0.1 4.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGO51370.1 - 0.00082 20.0 13.1 9.6 7.3 0.1 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGO51370.1 - 0.0089 15.7 9.3 0.99 9.2 0.1 5.2 7 0 0 7 7 7 2 TPR repeat TPR_1 PF00515.28 EGO51370.1 - 0.02 14.7 3.9 4.4 7.3 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGO51370.1 - 0.086 13.1 8.4 1.4 9.3 0.1 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGO51370.1 - 0.14 12.8 19.8 3.8 8.3 0.2 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGO51370.1 - 0.28 11.9 11.9 0.63 10.8 1.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4074 PF13293.6 EGO51371.1 - 0.21 11.9 7.3 0.081 13.2 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4074) GEN1_C PF18380.1 EGO51372.1 - 6.1 7.8 15.9 7.2 7.6 3.9 2.4 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain DUF4690 PF15756.5 EGO51374.1 - 0.015 15.9 0.2 0.69 10.6 0.0 2.4 2 1 1 3 3 3 0 Small Novel Rich in Cartilage EphA2_TM PF14575.6 EGO51375.1 - 0.17 12.8 0.0 0.59 11.1 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain NicO PF03824.16 EGO51375.1 - 0.28 10.5 0.4 0.42 9.9 0.0 1.4 2 0 0 2 2 2 0 High-affinity nickel-transport protein DUF3169 PF11368.8 EGO51375.1 - 0.33 10.4 3.0 3.2 7.2 2.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) MSA-2c PF12238.8 EGO51375.1 - 0.68 9.9 2.0 0.85 9.6 2.0 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF4190 PF13828.6 EGO51376.1 - 0.051 13.3 1.5 0.051 13.3 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) DUF2613 PF11021.8 EGO51376.1 - 0.63 10.2 2.9 2.4 8.3 2.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) m04gp34like PF12216.8 EGO51378.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Immune evasion protein MGC-24 PF05283.11 EGO51380.1 - 0.00029 21.3 0.2 0.00029 21.3 0.2 2.0 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin SKG6 PF08693.10 EGO51380.1 - 0.0018 17.7 1.0 0.0051 16.2 1.0 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Glyco_hydro_26 PF02156.15 EGO51382.1 - 2.6e-13 50.1 2.4 5.6e-13 49.0 1.9 1.7 1 1 1 2 2 2 1 Glycosyl hydrolase family 26 TSP9 PF11493.8 EGO51385.1 - 0.29 11.8 1.2 0.35 11.6 0.1 1.7 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 Rpp20 PF12328.8 EGO51386.1 - 4e-28 98.1 0.0 5.5e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EGO51386.1 - 6.2e-10 38.7 0.0 1.3e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 Alba Rogdi_lz PF10259.9 EGO51387.1 - 3e-86 289.2 0.3 3.6e-84 282.4 0.1 2.0 2 0 0 2 2 2 2 Rogdi leucine zipper containing protein NIPSNAP PF07978.13 EGO51388.1 - 2.7e-34 117.4 7.2 4.4e-31 107.2 0.2 2.6 3 0 0 3 3 3 2 NIPSNAP ATP-synt_J PF04911.12 EGO51389.1 - 1.7e-25 88.3 0.4 2e-25 88.1 0.4 1.1 1 0 0 1 1 1 1 ATP synthase j chain FSH1 PF03959.13 EGO51390.1 - 2.8e-57 193.8 0.0 4.4e-57 193.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EGO51390.1 - 0.00017 21.5 0.1 0.17 11.7 0.6 3.1 3 1 0 3 3 3 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EGO51390.1 - 0.2 10.9 0.4 0.46 9.7 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2722 PF10846.8 EGO51393.1 - 3.7e-06 26.2 5.9 6.9e-06 25.3 5.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 EGO51393.1 - 0.00038 20.6 10.0 0.00077 19.6 10.0 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 EGO51393.1 - 0.0031 16.3 14.5 0.0031 16.3 14.5 2.1 3 0 0 3 3 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal EPL1 PF10513.9 EGO51393.1 - 0.078 13.4 2.0 0.21 12.0 2.0 1.7 1 0 0 1 1 1 0 Enhancer of polycomb-like Presenilin PF01080.17 EGO51393.1 - 0.11 11.3 0.3 0.17 10.6 0.3 1.3 1 0 0 1 1 1 0 Presenilin eIF_4EBP PF05456.11 EGO51393.1 - 0.34 10.9 6.7 0.44 10.5 1.3 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Suf PF05843.14 EGO51393.1 - 1.3 9.0 8.8 2.3 8.2 8.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 EGO51393.1 - 1.6 7.6 7.0 2.7 6.9 7.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 EGO51393.1 - 2.1 7.9 30.0 4.3 6.9 30.0 1.4 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 EGO51393.1 - 2.1 9.0 14.9 9.1 6.9 10.6 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4175 PF13779.6 EGO51393.1 - 3 5.6 16.5 4.5 5.1 16.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ribosomal_S5 PF00333.20 EGO51393.1 - 5.3 7.1 6.8 25 5.0 0.8 2.9 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain UPF0560 PF10577.9 EGO51393.1 - 5.5 5.4 11.2 8.8 4.7 11.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Pectate_lyase_3 PF12708.7 EGO51394.1 - 1.9e-92 308.9 11.5 2.4e-82 275.9 3.7 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EGO51394.1 - 9.2e-08 31.7 0.7 0.007 16.0 0.0 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.6 EGO51394.1 - 9.7e-05 22.3 6.1 0.001 19.0 0.2 3.2 3 0 0 3 3 3 2 Right handed beta helix region DUF1180 PF06679.12 EGO51398.1 - 0.016 15.6 0.9 0.023 15.1 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Topo_Zn_Ribbon PF08272.11 EGO51400.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like RNase_H PF00075.24 EGO51401.1 - 0.029 14.5 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 RNase H tRNA-synt_1e PF01406.19 EGO51404.1 - 0.26 10.6 2.2 13 5.0 0.1 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain DUF1325 PF07039.11 EGO51404.1 - 1.5 8.9 6.9 4.8 7.3 0.1 3.1 3 0 0 3 3 3 0 SGF29 tudor-like domain RNase_H PF00075.24 EGO51405.1 - 0.063 13.5 0.0 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 RNase H RVT_3 PF13456.6 EGO51405.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like DUF4727 PF15856.5 EGO51405.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) VTC PF09359.10 EGO51407.1 - 1.7e-99 332.7 0.4 2.8e-99 332.0 0.0 1.5 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 EGO51407.1 - 3.4e-12 46.6 3.2 6.7e-12 45.7 3.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 EGO51407.1 - 2.8e-08 34.1 25.3 4.9e-05 23.4 0.1 4.9 2 2 1 4 4 4 2 SPX domain TrmB PF01978.19 EGO51407.1 - 0.0074 16.1 1.1 0.16 11.9 0.1 2.8 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB FixQ PF05545.11 EGO51407.1 - 0.041 13.9 2.3 0.099 12.6 2.3 1.7 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Angiomotin_C PF12240.8 EGO51407.1 - 0.059 12.9 1.1 0.34 10.4 1.6 1.9 2 0 0 2 2 2 0 Angiomotin C terminal Fe_dep_repress PF01325.19 EGO51407.1 - 0.067 13.4 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Phage_holin_3_6 PF07332.11 EGO51407.1 - 0.15 12.1 0.3 0.3 11.1 0.3 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Ank_2 PF12796.7 EGO51408.1 - 0.0029 18.2 0.0 0.14 12.7 0.0 2.3 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) BLOC1S3 PF15753.5 EGO51408.1 - 0.086 13.0 0.4 0.14 12.2 0.4 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 p450 PF00067.22 EGO51409.1 - 1.7e-47 162.3 0.0 2.2e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4813 PF16072.5 EGO51410.1 - 2.4 7.7 11.0 3.2 7.3 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Sugar_tr PF00083.24 EGO51411.1 - 4.2e-86 289.6 11.7 4.8e-86 289.4 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO51411.1 - 2.1e-30 105.9 45.5 5.8e-28 97.8 22.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGO51411.1 - 8.3e-10 37.7 0.5 8.3e-10 37.7 0.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EGO51411.1 - 2.9e-05 22.8 2.1 2.9e-05 22.8 2.1 2.8 2 1 1 3 3 3 1 MFS/sugar transport protein DUF1326 PF07040.11 EGO51411.1 - 0.2 11.6 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) MutS_V PF00488.21 EGO51412.1 - 8.7e-69 231.3 0.2 2.8e-68 229.7 0.0 2.0 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EGO51412.1 - 4e-35 121.8 1.8 4e-35 121.8 1.8 1.7 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EGO51412.1 - 8.1e-30 103.4 0.0 1.8e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EGO51412.1 - 8.6e-10 39.0 0.0 2.4e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EGO51412.1 - 3.8e-05 23.9 0.0 0.00011 22.5 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV DUF1964 PF09244.10 EGO51412.1 - 0.044 14.2 0.3 0.24 11.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1964) DUF4911 PF16256.5 EGO51412.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) Tnp_22_trimer PF17489.2 EGO51412.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 L1 transposable element trimerization domain RVT_3 PF13456.6 EGO51413.1 - 0.044 13.6 0.1 1.1 9.0 0.1 2.8 2 1 0 2 2 2 0 Reverse transcriptase-like Cys_Met_Meta_PP PF01053.20 EGO51414.1 - 8.6e-25 87.1 0.0 1.8e-20 72.8 0.0 2.6 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGO51414.1 - 0.0011 18.2 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II AAA PF00004.29 EGO51415.1 - 1.4e-57 193.8 0.0 3.2e-43 147.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EGO51415.1 - 1.4e-26 92.7 0.1 3.1e-26 91.6 0.1 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 EGO51415.1 - 5.1e-14 51.8 0.7 7.7e-09 35.2 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGO51415.1 - 1.7e-10 41.5 5.0 0.0017 18.8 0.3 4.6 2 2 2 4 4 4 2 AAA ATPase domain NACHT PF05729.12 EGO51415.1 - 3.3e-09 36.9 0.9 0.00011 22.1 0.0 4.2 4 0 0 4 4 4 1 NACHT domain AAA_2 PF07724.14 EGO51415.1 - 7.2e-09 36.0 0.0 0.00019 21.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 EGO51415.1 - 2.3e-07 30.5 0.0 2.3e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region RuvB_N PF05496.12 EGO51415.1 - 6.8e-06 25.9 0.0 0.015 15.1 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGO51415.1 - 8.6e-06 25.8 0.1 0.04 13.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGO51415.1 - 1.5e-05 25.5 0.4 0.16 12.5 0.1 3.5 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EGO51415.1 - 2.6e-05 24.4 0.2 0.26 11.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGO51415.1 - 3.2e-05 24.2 2.1 0.23 11.7 0.2 3.9 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EGO51415.1 - 4.1e-05 23.6 0.0 0.069 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EGO51415.1 - 7.1e-05 22.8 0.1 0.23 11.5 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 EGO51415.1 - 0.00061 19.1 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 EGO51415.1 - 0.0008 19.8 0.1 4.2 7.8 0.0 3.4 3 0 0 3 3 3 1 RNA helicase Sigma54_activ_2 PF14532.6 EGO51415.1 - 0.00084 19.5 0.0 0.058 13.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain PEX-2N PF09263.10 EGO51415.1 - 0.00092 19.5 0.1 2.2 8.7 0.1 2.7 2 0 0 2 2 2 2 Peroxisome biogenesis factor 1, N-terminal Sigma54_activat PF00158.26 EGO51415.1 - 0.001 18.8 0.5 0.22 11.2 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 EGO51415.1 - 0.001 18.4 0.3 0.39 10.0 0.1 2.7 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 EGO51415.1 - 0.0011 18.3 0.4 0.81 9.0 0.1 3.0 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGO51415.1 - 0.0012 18.6 2.2 0.76 9.5 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_28 PF13521.6 EGO51415.1 - 0.0037 17.5 0.6 0.95 9.7 0.3 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGO51415.1 - 0.0045 16.6 3.5 1.5 8.4 0.1 3.6 2 2 0 3 3 3 1 AAA domain ABC_tran PF00005.27 EGO51415.1 - 0.0053 17.3 0.0 2.2 8.8 0.0 2.8 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 EGO51415.1 - 0.0098 15.1 0.7 6.3 5.9 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain DUF2075 PF09848.9 EGO51415.1 - 0.01 15.1 0.2 9.3 5.4 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EGO51415.1 - 0.011 15.7 0.2 0.15 12.0 0.1 2.3 2 0 0 2 2 2 0 NTPase ATPase PF06745.13 EGO51415.1 - 0.011 15.1 0.1 3.3 7.0 0.0 2.7 2 0 0 2 2 2 0 KaiC Viral_helicase1 PF01443.18 EGO51415.1 - 0.012 15.4 0.0 4.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 EGO51415.1 - 0.012 15.3 0.7 0.69 9.7 0.1 3.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EGO51415.1 - 0.016 14.9 0.1 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EGO51415.1 - 0.02 15.3 0.8 0.37 11.1 0.0 3.0 4 0 0 4 4 2 0 AAA domain APS_kinase PF01583.20 EGO51415.1 - 0.034 14.0 0.3 0.18 11.7 0.1 2.3 2 1 1 3 3 2 0 Adenylylsulphate kinase ATPase_2 PF01637.18 EGO51415.1 - 0.2 11.5 0.0 16 5.3 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea CobU PF02283.16 EGO51415.1 - 0.24 11.0 1.3 0.34 10.5 0.0 2.0 2 0 0 2 2 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase T2SSE PF00437.20 EGO51415.1 - 0.28 10.2 2.8 1 8.4 0.2 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_17 PF13207.6 EGO51415.1 - 0.56 10.6 8.3 2.5 8.5 0.1 3.3 4 0 0 4 4 3 0 AAA domain MCM PF00493.23 EGO51416.1 - 3.1e-104 347.0 0.0 4.8e-104 346.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGO51416.1 - 5e-30 103.9 0.1 8.5e-30 103.2 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGO51416.1 - 2.9e-20 72.5 1.1 6.9e-20 71.3 1.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGO51416.1 - 4.1e-20 72.3 5.1 7.3e-20 71.5 2.6 2.4 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGO51416.1 - 1.5e-07 31.0 0.0 1.3e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGO51416.1 - 6.5e-07 29.4 0.3 5.9e-06 26.3 0.0 2.8 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 EGO51416.1 - 6e-05 22.8 0.1 0.00018 21.3 0.1 1.8 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase_C PF13335.6 EGO51416.1 - 0.00033 21.2 2.9 0.00058 20.4 0.3 2.8 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 EGO51416.1 - 0.025 14.4 0.0 0.085 12.7 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGO51416.1 - 0.17 11.6 0.1 0.85 9.3 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.9 EGO51417.1 - 6.6e-106 354.0 0.0 8.4e-106 353.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 RRS1 PF04939.12 EGO51418.1 - 2.3e-55 186.9 0.6 2.7e-55 186.7 0.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.27 EGO51419.1 - 3.3e-28 98.4 0.0 5.7e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain TNT PF14021.6 EGO51419.1 - 7.7 7.1 6.8 0.82 10.3 0.9 2.4 3 0 0 3 3 3 0 Tuberculosis necrotizing toxin Prenyltrans PF00432.21 EGO51421.1 - 1.2e-52 175.3 10.2 2.4e-11 43.1 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EGO51421.1 - 0.00061 19.0 0.1 0.17 11.0 0.0 3.5 1 1 4 5 5 5 2 Squalene-hopene cyclase N-terminal domain GLTT PF01744.20 EGO51422.1 - 0.0043 16.8 0.2 0.01 15.6 0.2 1.6 1 0 0 1 1 1 1 GLTT repeat (6 copies) Nse5 PF08691.10 EGO51422.1 - 0.044 12.5 1.1 0.074 11.7 1.1 1.3 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 zf-SCNM1 PF15803.5 EGO51422.1 - 0.12 12.0 6.6 0.047 13.3 4.0 1.7 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 zf-C2H2_jaz PF12171.8 EGO51422.1 - 0.48 10.8 2.2 1.4 9.3 2.2 1.9 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Complex1_LYR PF05347.15 EGO51423.1 - 1.4e-18 66.7 1.3 1.6e-18 66.4 1.3 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGO51423.1 - 7.7e-06 26.6 0.2 8.7e-06 26.4 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like FAA_hydrolase PF01557.18 EGO51424.1 - 4.6e-66 222.6 0.0 6.6e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 EGO51424.1 - 0.034 14.5 0.1 0.061 13.8 0.1 1.4 1 0 0 1 1 1 0 Type II transport protein GspH BAH PF01426.18 EGO51427.1 - 0.0004 20.2 0.2 0.00086 19.2 0.2 1.6 1 0 0 1 1 1 1 BAH domain MDM1 PF15501.6 EGO51427.1 - 0.0019 17.4 17.6 0.0019 17.4 17.6 2.1 2 0 0 2 2 2 1 Nuclear protein MDM1 PHD PF00628.29 EGO51427.1 - 0.005 16.7 1.8 0.013 15.3 1.8 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EGO51427.1 - 0.0062 16.8 0.3 0.015 15.6 0.3 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain BSP_II PF05432.11 EGO51427.1 - 0.072 12.8 20.0 0.14 11.8 20.0 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PRIMA1 PF16101.5 EGO51427.1 - 0.47 10.5 3.0 1.4 9.0 3.0 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 ATG22 PF11700.8 EGO51428.1 - 1e-194 647.7 10.5 1.2e-194 647.4 10.5 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Phage_holin_3_6 PF07332.11 EGO51428.1 - 0.84 9.7 0.0 0.84 9.7 0.0 3.7 4 1 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3602 PF12223.8 EGO51429.1 - 6e-23 81.3 6.5 6e-23 81.3 6.5 2.9 3 1 1 4 4 4 2 Protein of unknown function (DUF3602) HET PF06985.11 EGO51430.1 - 8.5e-07 29.4 0.2 1.3e-05 25.5 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF2401 PF10287.9 EGO51431.1 - 3.2e-69 233.0 0.0 4.9e-69 232.4 0.0 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EGO51431.1 - 7.3e-21 74.4 0.0 1.5e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) XPG_N PF00752.17 EGO51432.1 - 4.1e-33 113.9 0.0 1.1e-32 112.6 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGO51432.1 - 1.8e-26 92.3 0.0 4.2e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 EGO51432.1 - 0.00055 19.7 1.2 0.00055 19.7 1.2 5.0 3 0 0 3 3 3 1 Ubiquitin interaction motif PUB_1 PF18486.1 EGO51432.1 - 0.027 14.3 0.0 0.11 12.3 0.0 2.1 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain Barttin PF15462.6 EGO51432.1 - 1.6 8.5 9.4 3 7.6 2.9 2.9 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) LSM PF01423.22 EGO51433.1 - 6.7e-11 41.7 0.0 8.4e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGO51433.1 - 0.06 13.5 0.0 0.084 13.0 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain EZH2_N PF18601.1 EGO51434.1 - 1.2e-32 112.1 0.7 4.1e-32 110.3 0.7 2.0 1 0 0 1 1 1 1 EZH2 N-terminal domain Ezh2_MCSS PF18600.1 EGO51434.1 - 5.2e-23 80.4 0.1 9.7e-23 79.6 0.1 1.5 1 0 0 1 1 1 1 MCSS domain SET PF00856.28 EGO51434.1 - 1.2e-16 61.6 0.1 1.2e-16 61.6 0.1 4.7 5 2 0 5 5 5 1 SET domain preSET_CXC PF18264.1 EGO51434.1 - 0.00059 20.3 12.4 0.00059 20.3 12.4 2.9 1 1 2 3 3 3 1 CXC domain Pil1 PF13805.6 EGO51435.1 - 4.8e-121 403.3 0.1 2.7e-62 210.7 0.0 2.1 2 0 0 2 2 2 2 Eisosome component PIL1 NOA36 PF06524.12 EGO51435.1 - 4.1 6.6 6.7 7.5 5.8 6.7 1.4 1 0 0 1 1 1 0 NOA36 protein RRF PF01765.19 EGO51436.1 - 1.2e-26 93.7 0.7 1.6e-26 93.2 0.7 1.1 1 0 0 1 1 1 1 Ribosome recycling factor NPA PF16469.5 EGO51436.1 - 0.013 16.0 5.9 0.02 15.5 5.9 1.2 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 ARGLU PF15346.6 EGO51436.1 - 0.067 13.1 11.4 0.099 12.5 11.4 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 CREPT PF16566.5 EGO51436.1 - 0.28 11.3 5.2 0.5 10.5 5.2 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour MRI PF15325.6 EGO51436.1 - 0.98 10.5 7.4 0.53 11.4 4.1 2.1 2 0 0 2 2 2 0 Modulator of retrovirus infection UPF0164 PF03687.13 EGO51437.1 - 0.15 10.9 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) WD40 PF00400.32 EGO51438.1 - 9.2e-20 70.6 7.3 8.2e-06 26.5 0.0 10.4 10 0 0 10 10 10 7 WD domain, G-beta repeat SUR7 PF06687.12 EGO51439.1 - 5.5e-40 137.3 10.9 6.9e-40 136.9 10.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2207 PF09972.9 EGO51439.1 - 0.35 9.6 3.0 0.64 8.7 2.8 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Claudin_2 PF13903.6 EGO51439.1 - 1.1 9.0 16.3 0.033 14.0 9.8 1.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction 5TM-5TMR_LYT PF07694.12 EGO51439.1 - 1.2 8.7 16.0 0.034 13.7 7.8 2.2 2 1 0 2 2 2 0 5TMR of 5TMR-LYT Cwf_Cwc_15 PF04889.12 EGO51440.1 - 0.22 11.2 1.1 0.27 10.9 1.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Metallophos PF00149.28 EGO51441.1 - 7e-35 121.4 0.1 1e-34 120.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGO51441.1 - 7.9e-16 58.2 0.0 1.4e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_3_C PF01915.22 EGO51444.1 - 4.4e-66 222.7 0.0 9.7e-66 221.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO51444.1 - 5.4e-59 200.2 0.0 9.2e-59 199.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 EGO51444.1 - 3.1e-27 95.2 0.0 4.8e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 EGO51444.1 - 3.7e-24 84.6 1.0 7.8e-24 83.6 1.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_18 PF00704.28 EGO51445.1 - 1.5e-45 156.3 2.0 1.5e-45 156.3 2.0 2.2 2 1 1 3 3 3 1 Glycosyl hydrolases family 18 Hce2 PF14856.6 EGO51445.1 - 1.6e-29 102.2 6.5 2.4e-29 101.6 1.3 3.8 3 0 0 3 3 3 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.20 EGO51445.1 - 4.4e-09 36.3 0.0 0.0018 18.3 0.0 3.2 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.19 EGO51445.1 - 7.4e-05 23.1 8.8 7.4e-05 23.1 8.8 4.3 3 1 0 3 3 3 1 Chitin recognition protein LysM PF01476.20 EGO51447.1 - 1.1e-11 44.6 0.0 1.6e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 LysM domain Metallophos PF00149.28 EGO51448.1 - 4.1e-17 63.4 2.4 7.1e-17 62.6 2.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1708 PF08101.11 EGO51449.1 - 5e-173 576.2 0.0 6.7e-173 575.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) UDG PF03167.19 EGO51450.1 - 2.4e-22 79.6 0.1 4.1e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily NESP55 PF06390.12 EGO51451.1 - 0.21 11.2 1.2 0.46 10.0 1.2 1.5 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Mito_carr PF00153.27 EGO51452.1 - 1.1e-60 201.6 4.3 5.3e-20 71.2 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Stomoxyn PF11585.8 EGO51452.1 - 0.27 11.3 1.7 13 5.9 0.5 2.8 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn DUF4148 PF13663.6 EGO51452.1 - 0.56 10.4 0.0 0.56 10.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) PAF-AH_p_II PF03403.13 EGO51455.1 - 1.6e-54 184.9 0.0 3.3e-26 91.7 0.0 3.6 3 1 1 4 4 4 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EGO51455.1 - 2.4e-08 33.2 0.0 4.9e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EGO51455.1 - 3.6e-06 26.2 0.0 2.6e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.8 EGO51455.1 - 1.8e-05 24.1 0.0 0.03 13.6 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 EGO51455.1 - 0.18 11.3 0.0 2.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family SPX PF03105.19 EGO51455.1 - 7.1 6.4 9.1 5.7 6.7 7.6 1.6 2 0 0 2 2 2 0 SPX domain C166 PF17615.2 EGO51456.1 - 7.4e-08 32.7 0.2 1e-07 32.3 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function HsbA PF12296.8 EGO51456.1 - 0.0018 18.7 5.0 0.0089 16.4 2.6 2.6 2 1 1 3 3 3 1 Hydrophobic surface binding protein A Synaptonemal_3 PF15191.6 EGO51456.1 - 0.0078 16.0 0.4 0.95 9.3 0.0 2.4 2 1 0 2 2 2 2 Synaptonemal complex central element protein 3 NAD_binding_10 PF13460.6 EGO51458.1 - 0.0017 18.3 0.0 0.0052 16.7 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGO51458.1 - 0.017 14.7 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Glyco_transf_28 PF03033.20 EGO51459.1 - 2.6e-19 69.6 0.2 1e-11 45.1 0.1 2.7 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EGO51459.1 - 5.2e-07 28.8 0.0 9.8e-07 27.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 EGO51459.1 - 0.0002 21.7 0.0 0.00058 20.2 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 EGO51459.1 - 0.0019 18.2 0.0 0.0047 16.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_22 PF03901.17 EGO51460.1 - 1.6e-45 156.1 13.9 2.2e-45 155.7 13.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4079 PF13301.6 EGO51460.1 - 0.0035 17.5 2.1 2.4 8.3 0.5 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF4079) F_actin_cap_B PF01115.17 EGO51461.1 - 1.8e-105 351.9 0.0 2.1e-105 351.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 EGO51461.1 - 0.094 12.1 0.0 0.32 10.4 0.0 1.9 2 1 0 2 2 2 0 F-actin capping protein alpha subunit Epimerase PF01370.21 EGO51463.1 - 6.1e-18 65.2 0.0 7.8e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGO51463.1 - 3.7e-08 32.8 0.0 4.7e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGO51463.1 - 2.6e-05 23.8 0.0 5.2e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGO51463.1 - 0.0019 17.2 0.0 0.0053 15.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EGO51463.1 - 0.014 15.6 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EGO51463.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 KR domain Ldh_1_N PF00056.23 EGO51463.1 - 0.2 11.8 0.0 0.42 10.7 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain CBS PF00571.28 EGO51465.1 - 0.00023 21.5 0.0 1.4 9.4 0.0 2.9 2 1 0 2 2 2 2 CBS domain Mito_carr PF00153.27 EGO51466.1 - 8.4e-50 166.7 6.5 1.1e-18 66.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PNP_UDP_1 PF01048.20 EGO51467.1 - 0.0036 16.6 0.6 0.027 13.7 0.6 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_12 PF13424.6 EGO51468.1 - 3.7e-35 120.1 7.1 1.6e-09 37.9 0.0 6.6 2 2 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 EGO51468.1 - 7e-32 108.4 2.7 1.1e-07 31.4 0.0 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 EGO51468.1 - 5.8e-08 32.2 0.1 0.54 10.4 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGO51468.1 - 1.8e-07 31.7 2.2 1.5 9.6 2.8 5.9 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGO51468.1 - 3.2e-07 29.9 7.4 1.8 8.9 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGO51468.1 - 2.9e-06 26.9 1.0 1.6e-05 24.5 0.2 2.3 2 1 1 3 3 3 1 MalT-like TPR region TPR_8 PF13181.6 EGO51468.1 - 5.7e-06 26.1 0.6 2.6 8.5 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO51468.1 - 2.9e-05 24.5 0.4 6.9 7.3 0.0 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 EGO51468.1 - 3.4e-05 24.1 0.7 7.8 7.4 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGO51468.1 - 0.00011 21.8 0.7 28 4.7 0.1 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat AAA_22 PF13401.6 EGO51468.1 - 0.00037 20.8 0.0 0.0017 18.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EGO51468.1 - 0.00049 19.4 0.0 0.007 15.6 0.0 2.2 1 1 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 EGO51468.1 - 0.00054 20.6 5.0 84 4.4 0.0 6.9 5 3 3 8 8 7 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EGO51468.1 - 0.011 15.2 0.0 0.91 8.9 0.0 2.6 2 0 0 2 2 2 0 Coatomer epsilon subunit AAA_16 PF13191.6 EGO51468.1 - 0.039 14.4 0.0 0.22 11.9 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain DNA_pol_B_thumb PF14791.6 EGO51471.1 - 9.6e-26 89.8 0.6 2.6e-25 88.4 0.6 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 EGO51471.1 - 1.6e-22 79.8 0.0 3.8e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 EGO51471.1 - 8.4e-20 70.4 0.4 2.1e-19 69.1 0.2 1.9 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 EGO51471.1 - 1.1e-17 64.2 0.0 7.3e-17 61.5 0.1 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.8 EGO51471.1 - 0.08 13.2 0.0 18 5.6 0.0 2.6 1 1 1 2 2 2 0 Pathogenicity locus NTP_transf_2 PF01909.23 EGO51471.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Apidaecin PF00807.17 EGO51471.1 - 4.4 7.5 7.1 25 5.1 2.9 3.0 2 0 0 2 2 2 0 Apidaecin Mob1_phocein PF03637.17 EGO51472.1 - 6.2e-43 146.7 0.3 1.4e-42 145.6 0.3 1.5 1 1 0 1 1 1 1 Mob1/phocein family Methyltransf_25 PF13649.6 EGO51473.1 - 2.6e-13 50.5 0.0 9.6e-13 48.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO51473.1 - 4.8e-11 42.7 0.0 1.1e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGO51473.1 - 6e-11 42.3 0.0 9.4e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGO51473.1 - 5e-10 39.9 0.0 1.9e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGO51473.1 - 1.1e-07 31.1 0.1 1.7e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 EGO51473.1 - 9.4e-07 28.8 0.0 3e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO51473.1 - 7.3e-06 26.6 0.0 2e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO51473.1 - 8.4e-05 22.2 0.1 0.00017 21.2 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EGO51473.1 - 0.00013 21.9 0.1 0.00024 21.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGO51473.1 - 0.0003 20.2 0.0 0.00045 19.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 EGO51473.1 - 0.0007 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 EGO51473.1 - 0.0015 18.7 0.0 0.0032 17.6 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase PRMT5 PF05185.16 EGO51473.1 - 0.0032 17.3 0.0 0.0066 16.3 0.0 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EGO51473.1 - 0.0035 17.2 0.0 0.0061 16.4 0.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PCMT PF01135.19 EGO51473.1 - 0.0039 17.0 0.2 0.006 16.4 0.2 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EGO51473.1 - 0.011 15.7 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 EGO51473.1 - 0.016 14.8 0.3 0.031 13.8 0.2 1.5 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_16 PF10294.9 EGO51473.1 - 0.03 14.0 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase TehB PF03848.14 EGO51473.1 - 0.041 13.3 0.1 0.11 11.9 0.1 1.7 1 1 0 1 1 1 0 Tellurite resistance protein TehB Cons_hypoth95 PF03602.15 EGO51473.1 - 0.052 13.2 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 EGO51473.1 - 0.08 12.5 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PGM_PMM_I PF02878.16 EGO51474.1 - 4.4e-17 62.1 0.1 1.5e-07 31.2 0.0 2.6 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EGO51474.1 - 4.3e-12 46.0 0.8 1.4e-11 44.3 0.4 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 EGO51474.1 - 0.0055 16.9 0.0 0.018 15.2 0.0 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGO51474.1 - 0.0074 16.9 0.4 0.13 12.9 0.4 2.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II T3SS_ATPase_C PF18269.1 EGO51474.1 - 0.033 14.0 0.0 15 5.6 0.0 3.1 3 0 0 3 3 3 0 T3SS EscN ATPase C-terminal domain ERCC4 PF02732.15 EGO51475.1 - 5e-26 91.8 0.3 9.8e-26 90.8 0.1 1.6 2 0 0 2 2 2 1 ERCC4 domain Lum_binding PF00677.17 EGO51476.1 - 3.6e-45 151.8 1.9 5.7e-22 77.5 0.1 2.2 2 0 0 2 2 2 2 Lumazine binding domain Glyco_transf_17 PF04724.13 EGO51477.1 - 1.3e-30 106.7 0.0 2.6e-18 66.2 0.0 3.0 2 1 0 2 2 2 2 Glycosyltransferase family 17 CFEM PF05730.11 EGO51478.1 - 3.7e-13 49.3 11.5 6.1e-13 48.7 11.5 1.3 1 0 0 1 1 1 1 CFEM domain Peptidase_C15 PF01470.17 EGO51479.1 - 1.6e-12 48.0 0.0 0.0024 18.1 0.0 3.1 3 0 0 3 3 3 3 Pyroglutamyl peptidase Oxidored_FMN PF00724.20 EGO51480.1 - 4.9e-67 226.6 0.0 3.7e-66 223.7 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family tRNA-synt_1g PF09334.11 EGO51481.1 - 1.5e-140 468.4 0.1 5.2e-140 466.6 0.1 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGO51481.1 - 3.5e-05 22.3 6.5 0.0031 15.8 0.0 3.8 4 1 1 5 5 5 2 tRNA synthetases class I (I, L, M and V) GBP_C PF02841.14 EGO51481.1 - 5.3 6.3 16.0 1.1 8.6 0.2 2.1 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain BTB PF00651.31 EGO51482.1 - 7.8e-06 26.1 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain HET PF06985.11 EGO51484.1 - 3.6e-22 79.3 0.3 9.1e-22 78.0 0.2 1.7 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Mg_trans_NIPA PF05653.14 EGO51486.1 - 9.6e-15 54.5 9.9 1.4e-14 53.9 9.9 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EGO51486.1 - 8.8e-05 22.7 14.9 0.00059 20.0 0.3 2.7 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EGO51486.1 - 0.00038 19.8 0.2 0.00038 19.8 0.2 2.3 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport vATP-synt_E PF01991.18 EGO51487.1 - 9.9e-74 247.1 3.3 1.1e-73 246.9 3.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit PhoLip_ATPase_C PF16212.5 EGO51489.1 - 7.3e-74 248.7 28.1 7.3e-74 248.7 28.1 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGO51489.1 - 2.7e-20 71.8 0.4 6.7e-20 70.5 0.4 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGO51489.1 - 1.1e-12 47.9 0.0 5.8e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGO51489.1 - 1.2e-11 45.3 4.5 1.2e-07 32.3 1.8 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGO51489.1 - 0.00015 21.3 0.0 0.00015 21.3 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGO51489.1 - 0.0081 15.9 0.6 0.025 14.3 0.6 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Aldedh PF00171.22 EGO51490.1 - 1e-117 393.5 0.0 1.2e-117 393.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ACP PF06857.11 EGO51490.1 - 0.032 14.5 0.0 0.087 13.1 0.0 1.7 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) Protocadherin PF08374.11 EGO51491.1 - 0.091 12.7 0.6 0.095 12.7 0.6 1.1 1 0 0 1 1 1 0 Protocadherin SseC PF04888.12 EGO51491.1 - 0.81 9.2 3.3 0.95 9.0 3.3 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family ERCC4 PF02732.15 EGO51492.1 - 1.9e-20 73.7 0.0 4.3e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.6 EGO51492.1 - 0.0016 19.0 0.0 0.0046 17.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cytomega_UL84 PF06284.11 EGO51492.1 - 0.22 10.0 2.8 0.37 9.2 2.8 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein WH1 PF00568.23 EGO51494.1 - 3e-27 94.8 0.1 4.1e-27 94.3 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 EGO51494.1 - 0.13 12.2 0.4 0.26 11.2 0.4 1.5 1 0 0 1 1 1 0 WH2 motif TSP9 PF11493.8 EGO51494.1 - 7.6 7.3 5.8 11 6.8 0.4 2.5 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 eIF-1a PF01176.19 EGO51495.1 - 1.9e-21 75.6 0.1 2.6e-21 75.2 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 fn3_2 PF16893.5 EGO51497.1 - 9.5e-39 131.4 0.0 1.5e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EGO51497.1 - 1.1e-22 79.7 0.8 1.8e-22 79.0 0.8 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 EGO51497.1 - 1.3e-12 47.5 0.0 3.4e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 EGO51497.1 - 2.8e-10 40.4 0.0 4.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGO51497.1 - 0.0001 22.6 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 EGO51497.1 - 0.00062 20.0 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.21 EGO51497.1 - 0.0012 19.1 2.0 0.0031 17.8 0.0 2.6 2 1 0 2 2 2 1 Fibronectin type III domain LIG3_BRCT PF16759.5 EGO51497.1 - 0.2 12.0 0.0 0.43 10.9 0.0 1.5 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain adh_short PF00106.25 EGO51498.1 - 3.6e-09 36.4 0.0 2e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO51498.1 - 2.2e-07 30.7 0.0 7.4e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO51498.1 - 0.02 14.8 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 KR domain Pex19 PF04614.12 EGO51499.1 - 0.019 14.7 0.1 0.047 13.5 0.1 1.6 1 0 0 1 1 1 0 Pex19 protein family Tetraspanin PF00335.20 EGO51500.1 - 0.012 15.4 14.5 0.067 12.9 14.5 2.5 1 1 0 1 1 1 0 Tetraspanin family Sensor PF13796.6 EGO51500.1 - 0.019 15.0 1.8 0.019 15.0 1.8 2.6 3 0 0 3 3 3 0 Putative sensor Hum_adeno_E3A PF05393.11 EGO51500.1 - 0.14 12.2 2.5 3.9 7.5 0.5 2.4 2 1 0 2 2 2 0 Human adenovirus early E3A glycoprotein TMEM43 PF07787.12 EGO51500.1 - 0.18 11.2 2.7 0.58 9.5 0.0 2.3 1 1 1 2 2 2 0 Transmembrane protein 43 FxsA PF04186.13 EGO51500.1 - 0.24 11.6 7.3 0.74 10.0 1.2 3.0 1 1 1 3 3 3 0 FxsA cytoplasmic membrane protein DUF4191 PF13829.6 EGO51500.1 - 0.83 8.9 8.1 2 7.7 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) DUF4491 PF14898.6 EGO51500.1 - 4.7 7.7 7.8 17 5.9 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4491) CAP_N PF01213.19 EGO51502.1 - 0.54 9.7 2.7 0.25 10.8 0.2 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal SRF-TF PF00319.18 EGO51503.1 - 4.6e-21 74.0 0.1 6.4e-21 73.6 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ctr PF04145.15 EGO51505.1 - 1.9e-30 106.4 0.4 2.3e-30 106.1 0.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family zf-C2H2 PF00096.26 EGO51507.1 - 5.2e-11 42.4 9.1 5e-05 23.5 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO51507.1 - 3.6e-06 27.3 13.7 0.0019 18.9 1.7 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGO51507.1 - 4e-05 23.8 1.2 4e-05 23.8 1.2 3.0 3 1 0 3 3 3 2 Zinc-finger double domain BolA PF01722.18 EGO51507.1 - 0.039 14.2 0.1 6 7.2 0.0 2.4 2 0 0 2 2 2 0 BolA-like protein zf-C2H2_6 PF13912.6 EGO51507.1 - 0.049 13.6 5.4 3.5 7.8 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EGO51507.1 - 0.096 12.5 2.0 7.9 6.3 0.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 EGO51507.1 - 0.15 12.4 1.7 2 8.8 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 EGO51507.1 - 0.21 11.2 0.7 19 4.9 0.0 3.1 3 0 0 3 3 3 0 MYST family zinc finger domain zf-CHY PF05495.12 EGO51507.1 - 0.73 10.4 4.0 2.4 8.7 4.0 1.8 1 1 0 1 1 1 0 CHY zinc finger zf-C2HE PF16278.5 EGO51507.1 - 9 6.8 6.4 7 7.2 1.1 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Malate_synthase PF01274.22 EGO51508.1 - 1.6e-232 772.5 0.0 1.8e-232 772.3 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Lyase_1 PF00206.20 EGO51509.1 - 5.2e-111 371.0 0.0 7.4e-111 370.5 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EGO51509.1 - 3.4e-23 81.8 0.5 2.8e-22 78.9 0.1 2.6 2 0 0 2 2 2 1 Fumarase C C-terminus SHOCT PF09851.9 EGO51509.1 - 0.22 11.3 1.3 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 Short C-terminal domain Pkinase PF00069.25 EGO51510.1 - 8.9e-73 244.9 1.1 1.5e-71 240.9 1.1 2.3 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 EGO51510.1 - 6.3e-43 145.2 1.0 1.2e-42 144.3 1.0 1.5 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 EGO51510.1 - 6.2e-40 137.1 0.5 5.5e-37 127.5 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO51510.1 - 1e-05 24.7 0.1 2.4e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EGO51510.1 - 0.00036 20.0 0.0 0.00081 18.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGO51510.1 - 0.0009 18.6 1.7 0.0026 17.1 0.3 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGO51510.1 - 0.0016 18.1 0.1 0.003 17.2 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EGO51510.1 - 0.0071 16.3 0.0 0.024 14.6 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family SMC_N PF02463.19 EGO51511.1 - 2.1e-23 82.9 0.2 3.3e-23 82.3 0.2 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGO51511.1 - 6.1e-14 53.0 12.3 6.1e-14 53.0 12.3 5.5 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 EGO51511.1 - 1.9e-06 27.9 1.8 1.9e-06 27.9 1.8 3.2 2 1 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 EGO51511.1 - 0.0025 17.7 7.6 0.011 15.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EGO51511.1 - 0.0053 17.2 0.1 0.055 13.9 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EGO51511.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TLE_N PF03920.15 EGO51511.1 - 0.017 15.2 18.7 0.44 10.6 6.4 3.0 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain DUF2431 PF10354.9 EGO51511.1 - 0.77 10.0 3.6 11 6.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2431) DUF5069 PF16798.5 EGO51511.1 - 1.9 8.7 20.1 0.16 12.1 0.7 4.6 5 1 1 6 6 6 0 Domain of unknown function (DUF5069) Nup_retrotrp_bd PF10599.9 EGO51513.1 - 0.011 16.4 0.1 0.017 15.8 0.1 1.3 1 0 0 1 1 1 0 Retro-transposon transporting motif GATA PF00320.27 EGO51515.1 - 9.6e-17 60.3 2.0 1.8e-16 59.4 2.0 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 EGO51515.1 - 3.3e-12 46.0 0.8 6.8e-12 45.0 0.8 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MFS_1 PF07690.16 EGO51516.1 - 5.1e-26 91.4 46.5 9.8e-25 87.2 36.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily EPV_E5 PF08135.11 EGO51516.1 - 1.6 9.1 5.7 0.3 11.5 0.7 2.5 2 0 0 2 2 2 0 Major transforming protein E5 family SPX PF03105.19 EGO51516.1 - 9.4 6.0 8.6 29 4.4 8.7 1.7 1 1 0 1 1 1 0 SPX domain Wbp11 PF09429.10 EGO51517.1 - 4.8e-21 75.0 14.3 4.8e-21 75.0 14.3 2.2 2 1 0 2 2 2 1 WW domain binding protein 11 Lipoprotein_7 PF01540.16 EGO51517.1 - 0.0016 17.8 2.6 0.0023 17.3 2.6 1.2 1 0 0 1 1 1 1 Adhesin lipoprotein DUF2972 PF11186.8 EGO51517.1 - 0.016 15.1 0.8 0.025 14.5 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) Tup_N PF08581.10 EGO51517.1 - 0.036 14.4 2.2 0.076 13.3 2.2 1.6 1 0 0 1 1 1 0 Tup N-terminal DUF3450 PF11932.8 EGO51517.1 - 0.39 10.0 8.8 0.64 9.3 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FUSC PF04632.12 EGO51517.1 - 0.4 9.2 1.1 0.54 8.7 1.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ASD2 PF08687.11 EGO51517.1 - 0.6 9.6 11.7 0.16 11.5 7.9 1.8 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 TMPIT PF07851.13 EGO51517.1 - 1.7 7.8 3.2 2.6 7.2 3.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein Pkinase PF00069.25 EGO51518.1 - 8.4e-60 202.4 0.0 7.4e-59 199.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO51518.1 - 2.7e-28 98.9 0.2 1e-19 70.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EGO51518.1 - 0.0021 18.7 0.3 0.0069 17.1 0.3 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EGO51518.1 - 0.0045 16.4 0.1 0.018 14.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGO51518.1 - 0.0086 16.0 0.7 0.11 12.5 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EGO51518.1 - 0.017 14.4 0.0 0.064 12.6 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGO51518.1 - 0.035 13.1 0.0 0.059 12.3 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain CFEM PF05730.11 EGO51519.1 - 0.061 13.4 6.1 0.12 12.5 6.1 1.5 1 0 0 1 1 1 0 CFEM domain HET PF06985.11 EGO51520.1 - 1.4e-29 103.3 0.4 2.6e-29 102.5 0.4 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4355 PF14265.6 EGO51521.1 - 0.042 14.1 9.7 0.25 11.6 10.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) YcbB PF08664.10 EGO51521.1 - 0.54 10.3 6.4 1.2 9.2 6.4 1.6 1 0 0 1 1 1 0 YcbB domain DEAD PF00270.29 EGO51524.1 - 5.3e-40 137.0 0.0 8.7e-40 136.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO51524.1 - 3.5e-25 88.5 0.3 1e-23 83.8 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO51524.1 - 3.5e-09 36.9 0.0 7.3e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4844 PF16133.5 EGO51524.1 - 0.073 13.6 0.5 0.19 12.3 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) CMS1 PF14617.6 EGO51524.1 - 0.1 11.9 0.0 0.45 9.8 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Rpr2 PF04032.16 EGO51525.1 - 1.9e-23 82.5 1.5 7.1e-23 80.7 1.5 1.9 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain HNH_5 PF14279.6 EGO51525.1 - 0.04 13.8 0.7 0.076 12.9 0.7 1.5 1 0 0 1 1 1 0 HNH endonuclease SUIM_assoc PF16619.5 EGO51525.1 - 0.06 13.4 10.1 1.1 9.3 1.2 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DASH_Hsk3 PF08227.11 EGO51526.1 - 1.2e-19 70.4 3.6 1.2e-19 70.4 3.6 1.8 2 0 0 2 2 2 1 DASH complex subunit Hsk3 like ApbA PF02558.16 EGO51527.1 - 2.2e-26 92.4 0.0 3.2e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EGO51527.1 - 3.2e-25 88.7 0.0 5.4e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal TALPID3 PF15324.6 EGO51528.1 - 2 6.0 10.2 2.6 5.6 10.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Mito_fiss_reg PF05308.11 EGO51530.1 - 7 6.7 7.2 9.5 6.2 7.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Cyclin PF08613.11 EGO51533.1 - 1.4e-08 35.3 1.9 2.3e-08 34.6 0.0 2.3 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EGO51533.1 - 0.0019 17.9 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain SOG2 PF10428.9 EGO51535.1 - 6.4e-82 276.4 0.0 6.4e-82 276.4 0.0 3.8 1 1 2 3 3 3 1 RAM signalling pathway protein SUIM_assoc PF16619.5 EGO51535.1 - 0.12 12.4 4.0 0.34 11.0 4.0 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Pyrid_oxidase_2 PF13883.6 EGO51536.1 - 4e-41 140.8 3.4 3.8e-40 137.6 3.4 2.2 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RPA43_OB PF17875.1 EGO51536.1 - 0.23 12.1 7.3 7.7 7.2 5.1 2.4 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Ribosomal_S30 PF04758.14 EGO51537.1 - 3.5e-30 104.0 10.0 3.8e-30 103.9 10.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 DFP PF04127.15 EGO51538.1 - 8.1e-13 48.6 0.0 4e-05 23.5 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein TPPII_N PF12583.8 EGO51538.1 - 8.4 7.0 7.4 4.5 7.9 2.4 2.2 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal CorA PF01544.18 EGO51539.1 - 6e-14 52.0 0.7 9.8e-14 51.3 0.7 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DDE_Tnp_ISL3 PF01610.17 EGO51539.1 - 0.0044 16.8 0.1 0.007 16.1 0.1 1.2 1 0 0 1 1 1 1 Transposase F-box-like PF12937.7 EGO51540.1 - 0.066 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 F-box-like Sortilin-Vps10 PF15902.5 EGO51540.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, DEAD PF00270.29 EGO51541.1 - 6.3e-45 153.1 0.0 8.8e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO51541.1 - 3.1e-29 101.6 0.0 5e-28 97.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EGO51541.1 - 0.0016 17.2 0.0 0.0026 16.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EGO51541.1 - 0.0051 16.8 0.0 0.0081 16.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 EGO51541.1 - 0.04 13.2 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 SecA DEAD-like domain Ipi1_N PF12333.8 EGO51542.1 - 9e-31 106.5 0.1 9e-31 106.5 0.1 2.2 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.6 EGO51542.1 - 0.0025 18.2 0.1 0.0068 16.8 0.0 1.7 2 0 0 2 2 2 1 HEAT repeats Robl_LC7 PF03259.17 EGO51543.1 - 9.9e-11 41.3 0.1 1.6e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 Roadblock/LC7 domain LAMTOR5 PF16672.5 EGO51543.1 - 0.0093 15.9 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 MFS_1 PF07690.16 EGO51545.1 - 6.6e-42 143.7 28.8 1e-36 126.6 23.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO51545.1 - 4.5e-09 35.7 3.3 4.5e-09 35.7 3.3 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EGO51545.1 - 0.022 13.2 2.0 0.037 12.4 2.0 1.3 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) CENP-O PF09496.10 EGO51547.1 - 4.4e-73 245.8 0.0 6e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component RNA_capsid PF03035.14 EGO51547.1 - 0.077 13.0 0.7 0.18 11.8 0.7 1.6 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein zf-C3H2C3 PF17122.5 EGO51547.1 - 0.68 10.0 4.7 0.41 10.7 0.7 2.2 2 0 0 2 2 2 0 Zinc-finger Acatn PF13000.7 EGO51548.1 - 7.1e-165 549.6 21.7 1.9e-83 280.9 6.6 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 BphX PF06139.12 EGO51548.1 - 0.0012 18.8 0.1 0.18 11.8 0.0 2.9 2 0 0 2 2 2 2 BphX-like DUF5493 PF17597.2 EGO51548.1 - 4.7 7.5 7.2 6.8 7.0 0.3 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5493) Amidase PF01425.21 EGO51549.1 - 1.3e-74 251.8 0.0 1.7e-74 251.4 0.0 1.1 1 0 0 1 1 1 1 Amidase p450 PF00067.22 EGO51550.1 - 4.3e-35 121.4 0.2 9.4e-25 87.3 0.1 3.1 2 1 0 2 2 2 2 Cytochrome P450 TipAS PF07739.13 EGO51550.1 - 0.19 12.3 0.0 0.39 11.3 0.0 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain DUF3715 PF12509.8 EGO51551.1 - 0.011 15.8 0.4 0.12 12.3 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3715) Hemagglutinin PF00509.18 EGO51551.1 - 1.6 7.1 4.9 3.6 5.9 4.9 1.5 1 0 0 1 1 1 0 Haemagglutinin Vac_Fusion PF02346.16 EGO51551.1 - 1.9 8.2 4.4 13 5.4 0.2 4.0 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 PAM2 PF07145.15 EGO51551.1 - 2.7 7.9 13.7 0.11 12.3 0.9 4.2 4 0 0 4 4 4 0 Ataxin-2 C-terminal region Mid2 PF04478.12 EGO51552.1 - 2.3e-05 24.3 1.6 2.3e-05 24.3 1.6 2.1 2 1 0 2 2 2 1 Mid2 like cell wall stress sensor Lipoprotein_2 PF00921.17 EGO51552.1 - 0.047 13.2 3.4 0.065 12.8 3.4 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein Utp14 PF04615.13 EGO51552.1 - 0.29 9.6 5.0 0.34 9.5 5.0 1.1 1 0 0 1 1 1 0 Utp14 protein PEP-CTERM PF07589.11 EGO51552.1 - 0.34 11.1 1.4 3.8 7.7 0.4 2.5 2 0 0 2 2 2 0 PEP-CTERM motif Plasmodium_Vir PF05795.11 EGO51552.1 - 0.79 9.1 9.9 1 8.7 9.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SPX PF03105.19 EGO51552.1 - 1.9 8.3 10.5 2.4 8.0 10.5 1.3 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 EGO51552.1 - 1.9 6.9 6.1 2.1 6.8 6.1 1.1 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 EGO51552.1 - 4.8 5.7 6.8 6.3 5.4 6.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Glyco_hydro_18 PF00704.28 EGO51553.1 - 1.6e-13 51.1 0.1 2.3e-13 50.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Myb_DNA-binding PF00249.31 EGO51555.1 - 4e-15 55.7 0.2 2.9e-08 33.8 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO51555.1 - 2e-10 40.8 0.0 6.8e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EGO51555.1 - 7.4e-05 22.8 0.1 0.76 9.8 0.0 2.8 2 0 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EGO51555.1 - 0.039 14.2 0.0 0.095 12.9 0.0 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Ribosomal_S4e PF00900.20 EGO51556.1 - 1.4e-37 127.4 0.5 3.7e-37 126.1 0.5 1.7 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EGO51556.1 - 1.2e-24 85.7 0.0 2e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EGO51556.1 - 4.2e-19 68.4 5.3 8.5e-19 67.4 5.3 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EGO51556.1 - 1e-05 25.1 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EGO51556.1 - 4.9e-05 23.1 1.9 4.9e-05 23.1 1.9 2.8 3 0 0 3 3 3 1 KOW motif FAD-oxidase_C PF02913.19 EGO51558.1 - 9.5e-61 205.6 0.1 1.5e-60 204.9 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGO51558.1 - 4.6e-34 117.1 0.0 1.1e-33 115.8 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 EGO51558.1 - 0.07 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS RdRP PF05183.12 EGO51559.1 - 6.6e-177 589.7 0.0 9.4e-177 589.2 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 EGO51559.1 - 0.003 17.3 0.0 0.0065 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pex14_N PF04695.13 EGO51562.1 - 0.0095 16.6 7.4 0.017 15.8 7.4 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Shisa PF13908.6 EGO51562.1 - 2.1 8.6 7.3 3.2 7.9 7.3 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator 2OG-FeII_Oxy_3 PF13640.6 EGO51563.1 - 9.6e-12 45.6 0.0 1.8e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PI-PLC-X PF00388.19 EGO51564.1 - 1.9e-59 199.4 0.0 7.2e-59 197.5 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGO51564.1 - 1.2e-38 132.0 0.0 2.8e-38 130.8 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Spt20 PF12090.8 EGO51565.1 - 0.005 16.5 15.7 0.0064 16.1 15.7 1.2 1 0 0 1 1 1 1 Spt20 family DUF4407 PF14362.6 EGO51565.1 - 0.022 14.1 1.6 0.032 13.6 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 EGO51565.1 - 0.026 14.5 13.0 0.03 14.3 13.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 EGO51565.1 - 0.051 12.5 13.9 0.075 12.0 13.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4770 PF15994.5 EGO51565.1 - 0.06 13.6 6.3 0.11 12.7 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Neur_chan_memb PF02932.16 EGO51565.1 - 0.16 12.0 1.5 0.18 11.9 1.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4834 PF16118.5 EGO51565.1 - 0.65 11.0 9.8 1.6 9.8 9.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 EGO51565.1 - 1.3 7.7 5.2 1.5 7.5 5.2 1.1 1 0 0 1 1 1 0 Presenilin DUF5421 PF17458.2 EGO51565.1 - 1.7 8.0 7.5 2.5 7.4 7.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) GTA_holin_3TM PF11351.8 EGO51565.1 - 2.3 8.8 5.8 19 5.8 4.2 2.2 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release Androgen_recep PF02166.16 EGO51565.1 - 3.2 6.5 15.6 4.4 6.0 15.6 1.1 1 0 0 1 1 1 0 Androgen receptor DUF4820 PF16091.5 EGO51565.1 - 6 6.2 8.9 8.1 5.7 8.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4820) Fungal_trans PF04082.18 EGO51566.1 - 3.7e-09 36.0 0.6 6.8e-09 35.1 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EGO51566.1 - 6.9e-09 35.7 12.0 0.00072 19.9 1.5 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO51566.1 - 8.3e-06 26.2 8.5 0.056 14.3 0.5 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_clus PF00172.18 EGO51566.1 - 8.4e-06 25.8 9.7 8.4e-06 25.8 9.7 2.2 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 EGO51566.1 - 0.0011 19.3 3.1 0.0011 19.3 3.1 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EGO51566.1 - 0.0058 16.6 1.2 0.0058 16.6 1.2 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGO51566.1 - 0.017 15.4 3.4 0.61 10.4 0.6 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Cupin_2 PF07883.11 EGO51567.1 - 0.011 15.5 0.6 0.014 15.1 0.6 1.2 1 0 0 1 1 1 0 Cupin domain CFEM PF05730.11 EGO51569.1 - 1.1e-06 28.7 7.9 1.5e-06 28.2 7.9 1.2 1 0 0 1 1 1 1 CFEM domain CMS1 PF14617.6 EGO51570.1 - 2.6e-113 377.5 4.0 2.9e-113 377.4 4.0 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EGO51570.1 - 5.7e-08 32.7 0.1 1.1e-07 31.7 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase PQ-loop PF04193.14 EGO51571.1 - 1.4e-17 63.2 8.7 2e-16 59.5 1.2 2.9 2 1 1 3 3 3 2 PQ loop repeat DUF2070 PF09843.9 EGO51571.1 - 0.79 7.9 3.5 1.1 7.5 3.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DsbD PF02683.15 EGO51571.1 - 1.6 8.6 6.6 0.27 11.1 0.5 2.0 1 1 1 2 2 2 0 Cytochrome C biogenesis protein transmembrane region Ras PF00071.22 EGO51572.1 - 1.7e-51 174.1 0.0 1.9e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO51572.1 - 7.7e-19 68.1 0.0 1.1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO51572.1 - 5.3e-09 35.8 0.0 6.5e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGO51572.1 - 4.5e-06 26.3 0.3 4.2e-05 23.2 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGO51572.1 - 1.1e-05 25.5 0.0 0.023 14.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGO51572.1 - 0.0005 20.1 0.0 0.00073 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGO51572.1 - 0.056 12.6 0.0 2.5 7.2 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.22 EGO51572.1 - 0.066 12.4 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 EGO51572.1 - 0.097 13.1 0.3 0.28 11.6 0.3 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 EGO51572.1 - 0.099 11.9 0.0 0.77 9.0 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 EGO51572.1 - 0.18 12.1 0.2 1.6 9.0 0.1 2.4 1 1 1 2 2 2 0 AAA domain DUF3357 PF11837.8 EGO51574.1 - 0.00097 19.6 0.0 0.0031 17.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) Serglycin PF04360.12 EGO51574.1 - 0.061 13.3 1.3 0.13 12.2 1.3 1.4 1 0 0 1 1 1 0 Serglycin DotU PF09850.9 EGO51574.1 - 0.075 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Type VI secretion system protein DotU CE2_N PF17996.1 EGO51574.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal SDA1 PF05285.12 EGO51575.1 - 0.024 14.1 11.6 0.35 10.3 9.6 2.1 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 EGO51575.1 - 0.075 11.3 10.5 0.12 10.7 10.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 EGO51575.1 - 0.43 9.7 9.1 1 8.5 3.2 3.1 3 0 0 3 3 3 0 ZIP Zinc transporter Adeno_E3_CR2 PF02439.15 EGO51575.1 - 0.57 10.0 1.6 1.4 8.7 1.6 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Presenilin PF01080.17 EGO51575.1 - 4.8 5.8 6.8 8.9 5.0 6.8 1.4 1 0 0 1 1 1 0 Presenilin CytB6-F_Fe-S PF08802.10 EGO51575.1 - 5.5 7.1 5.7 1 9.5 0.4 2.2 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit SURF1 PF02104.15 EGO51577.1 - 8.6e-47 159.6 0.0 1.1e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T_C PF15511.6 EGO51578.1 - 1.7e-30 105.3 0.0 2.9e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGO51578.1 - 5.1e-08 33.2 0.0 9.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 EGO51578.1 - 3.4e-05 24.2 0.0 7.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGO51578.1 - 0.0011 19.2 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ras PF00071.22 EGO51579.1 - 1.3e-52 177.7 0.0 1.5e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO51579.1 - 7.9e-21 74.5 0.0 1.4e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO51579.1 - 1.2e-06 28.0 0.0 1.9e-06 27.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.22 EGO51580.1 - 1e-11 44.5 0.0 2.3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.9 EGO51580.1 - 2.6 6.5 29.7 1.2 7.7 19.8 2.0 2 0 0 2 2 2 0 Macoilin family Dapper PF15268.6 EGO51580.1 - 5.4 5.8 30.9 7.1 5.3 30.9 1.1 1 0 0 1 1 1 0 Dapper Hamartin PF04388.12 EGO51580.1 - 8 5.0 20.2 0.61 8.7 14.9 1.6 2 0 0 2 2 2 0 Hamartin protein SET PF00856.28 EGO51581.1 - 1e-13 52.0 0.0 3.1e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 SET domain Pap_E4 PF02711.14 EGO51581.1 - 8.8 7.4 9.9 35 5.5 7.0 2.5 2 0 0 2 2 2 0 E4 protein Coq4 PF05019.13 EGO51582.1 - 7.9e-95 316.4 0.0 1.2e-94 315.7 0.0 1.3 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.20 EGO51583.1 - 1.3e-41 141.3 5.3 1.5e-41 141.1 5.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain ApbA PF02558.16 EGO51584.1 - 1.3e-31 109.3 0.0 2e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EGO51584.1 - 6.3e-12 45.8 0.0 1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Sas10_Utp3 PF04000.15 EGO51585.1 - 8.3e-15 55.2 0.1 8.3e-15 55.2 0.1 2.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF2076 PF09849.9 EGO51585.1 - 0.00053 20.1 29.5 0.0057 16.7 29.6 2.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EGO51585.1 - 0.0032 17.5 5.8 0.005 16.9 5.8 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EGO51585.1 - 0.011 16.2 0.2 0.011 16.2 0.2 2.1 2 0 0 2 2 2 0 GCK domain CX9C PF16860.5 EGO51585.1 - 0.076 13.0 3.7 0.16 12.0 3.7 1.6 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, RF-1 PF00472.20 EGO51585.1 - 1.5 8.8 7.7 0.79 9.7 5.3 1.8 2 0 0 2 2 2 0 RF-1 domain Trypan_glycop_C PF10659.9 EGO51585.1 - 2.8 8.4 11.3 0.13 12.6 2.4 2.4 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain UBX PF00789.20 EGO51586.1 - 1.2e-13 51.0 0.0 2.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 EGO51586.1 - 0.0037 17.4 0.0 0.14 12.3 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin-like TFIIA PF03153.13 EGO51586.1 - 0.077 13.0 22.0 0.12 12.4 22.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.10 EGO51586.1 - 0.077 12.4 27.4 0.12 11.8 27.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hamartin PF04388.12 EGO51586.1 - 0.11 11.2 15.0 0.13 10.9 15.0 1.1 1 0 0 1 1 1 0 Hamartin protein Fmp27_WPPW PF10359.9 EGO51586.1 - 0.26 10.1 6.5 0.42 9.4 6.5 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain SelK_SelG PF10961.8 EGO51586.1 - 3.7 8.2 9.0 0.13 12.9 1.5 2.5 2 1 1 3 3 3 0 Selenoprotein SelK_SelG PRTP PF01366.18 EGO51586.1 - 4.5 5.2 9.7 7.4 4.5 9.7 1.4 1 0 0 1 1 1 0 Herpesvirus processing and transport protein RRM_1 PF00076.22 EGO51587.1 - 0.00047 19.9 0.0 0.0009 19.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EGO51588.1 - 5.2e-23 80.9 9.9 7.2e-06 26.7 0.1 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO51588.1 - 0.0057 16.9 0.0 1.3 9.4 0.0 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGO51588.1 - 0.023 15.2 0.4 13 6.4 0.1 3.0 2 0 0 2 2 2 0 PQQ-like domain Cytochrom_D1 PF02239.16 EGO51588.1 - 0.052 12.1 0.4 19 3.6 0.0 3.1 3 0 0 3 3 3 0 Cytochrome D1 heme domain PD40 PF07676.12 EGO51588.1 - 0.053 13.5 2.4 2.3 8.3 0.1 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat BUD22 PF09073.10 EGO51588.1 - 4.7 6.4 8.0 8 5.7 8.0 1.3 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 EGO51588.1 - 6.5 4.7 15.8 11 4.0 15.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Metallophos PF00149.28 EGO51589.1 - 2.4e-12 47.8 0.1 1.7e-11 45.0 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGO51589.1 - 6.8e-09 36.1 0.0 1.8e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EGO51589.1 - 0.085 12.2 0.0 3.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily IPP-2 PF04979.14 EGO51589.1 - 1.5 9.6 12.9 0.063 14.0 1.2 2.9 3 0 0 3 3 3 0 Protein phosphatase inhibitor 2 (IPP-2) DUF4611 PF15387.6 EGO51589.1 - 4.9 7.4 14.3 6.8 7.0 0.9 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Pet191_N PF10203.9 EGO51591.1 - 4.1e-27 94.3 3.5 5.4e-27 93.9 3.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 DUF4695 PF15766.5 EGO51591.1 - 0.024 14.8 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) COBRA PF04833.15 EGO51591.1 - 0.039 13.9 0.3 0.051 13.5 0.3 1.2 1 0 0 1 1 1 0 COBRA-like protein Cmc1 PF08583.10 EGO51591.1 - 0.27 11.3 3.5 4.4 7.4 0.5 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 EGO51591.1 - 8.5 6.5 8.0 3.4 7.8 0.5 2.9 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Abhydro_lipase PF04083.16 EGO51592.1 - 4e-23 80.7 0.1 7.3e-23 79.9 0.1 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EGO51592.1 - 6.4e-22 78.4 0.1 1.9e-21 76.8 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO51592.1 - 0.00083 18.7 0.0 0.062 12.6 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 EGO51592.1 - 0.011 15.4 0.1 3.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase (FSH1) bVLRF1 PF18826.1 EGO51594.1 - 1e-62 210.4 0.1 2.2e-62 209.4 0.1 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 EGO51594.1 - 3.7e-07 30.3 0.0 9.6e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGO51594.1 - 0.0059 17.0 0.3 0.019 15.4 0.3 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EGO51594.1 - 0.096 13.3 0.0 0.3 11.7 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) CTU2 PF10288.9 EGO51594.1 - 5.7 7.2 6.5 2 8.7 0.8 2.7 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 CFEM PF05730.11 EGO51596.1 - 0.00051 20.1 2.2 0.00051 20.1 2.2 3.3 3 0 0 3 3 3 1 CFEM domain Zn_clus PF00172.18 EGO51598.1 - 2.5e-08 33.9 11.9 3.8e-08 33.3 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Annexin PF00191.20 EGO51599.1 - 1.9e-18 66.2 0.1 4.5e-05 23.4 0.0 4.4 4 0 0 4 4 4 4 Annexin DUF1180 PF06679.12 EGO51600.1 - 0.079 13.4 0.8 0.15 12.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) GPI2 PF06432.11 EGO51601.1 - 4.8e-140 465.8 0.2 5.6e-140 465.6 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Cytochrom_B561 PF03188.16 EGO51601.1 - 0.47 10.6 4.4 0.094 12.9 0.5 1.7 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 BAT2_N PF07001.11 EGO51601.1 - 0.6 10.5 6.3 0.07 13.6 1.3 1.8 2 0 0 2 2 2 0 BAT2 N-terminus TAL_FSA PF00923.19 EGO51602.1 - 9.6e-94 313.9 0.2 1.1e-93 313.7 0.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase HydF_dimer PF18128.1 EGO51602.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Hydrogen maturase F dimerization domain SNase PF00565.17 EGO51604.1 - 4.8e-71 236.1 4.4 6.7e-22 78.0 0.0 5.8 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EGO51604.1 - 5e-24 84.7 0.0 1.8e-23 82.9 0.0 1.9 2 0 0 2 2 2 1 Tudor domain SMN PF06003.12 EGO51604.1 - 8.4e-06 25.2 0.0 2.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Sod_Cu PF00080.20 EGO51605.1 - 4.8e-47 159.7 5.3 5.6e-47 159.5 5.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CNH PF00780.22 EGO51607.1 - 2.8e-69 233.8 0.0 4.5e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EGO51607.1 - 6.6e-35 121.0 1.6 1e-34 120.4 1.6 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 EGO51607.1 - 1.2e-10 41.6 0.0 9.4e-10 38.7 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EGO51607.1 - 0.00015 22.3 0.0 0.013 16.0 0.0 2.9 3 0 0 3 3 3 1 PH domain PH_16 PF17838.1 EGO51607.1 - 0.0038 17.1 0.0 0.7 9.7 0.0 2.4 2 0 0 2 2 2 2 PH domain adh_short_C2 PF13561.6 EGO51609.1 - 5.8e-53 179.9 0.0 8.4e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO51609.1 - 4.9e-37 127.3 0.2 7.1e-37 126.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO51609.1 - 1.6e-10 41.2 0.0 2.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGO51609.1 - 0.0077 15.7 0.1 0.069 12.5 0.1 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGO51609.1 - 0.0088 15.5 0.0 0.015 14.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Carboxyl_trans PF01039.22 EGO51610.1 - 1.2e-134 449.7 0.0 1.5e-134 449.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EGO51610.1 - 0.0014 18.1 0.1 0.49 9.9 0.1 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.24 EGO51611.1 - 2.1e-44 151.4 1.9 3.7e-44 150.5 1.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGO51611.1 - 7.6e-26 90.2 0.2 1.3e-25 89.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGO51611.1 - 4.7e-23 82.0 0.4 1.1e-22 80.8 0.4 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGO51611.1 - 1.4e-15 57.7 0.2 2.3e-15 57.0 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EGO51611.1 - 8.4e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal NUDIX PF00293.28 EGO51612.1 - 4.5e-08 33.2 0.1 5.5e-07 29.7 0.1 2.0 1 1 0 1 1 1 1 NUDIX domain DLH PF01738.18 EGO51613.1 - 2e-16 60.2 0.0 2.5e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family MMR_HSR1 PF01926.23 EGO51614.1 - 3e-11 43.4 0.0 6.8e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO51614.1 - 0.00051 20.0 0.7 1.2 9.0 0.5 3.6 3 2 0 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 EGO51614.1 - 0.0086 15.6 0.1 0.026 14.0 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGO51614.1 - 0.021 14.9 0.1 0.4 10.7 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Arf PF00025.21 EGO51614.1 - 0.055 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_18 PF13238.6 EGO51614.1 - 0.18 12.4 2.1 0.2 12.2 0.1 2.1 2 1 0 2 2 2 0 AAA domain IIGP PF05049.13 EGO51614.1 - 0.2 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 EGO51614.1 - 0.49 10.6 1.5 2.4 8.4 0.0 2.7 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase HCO3_cotransp PF00955.21 EGO51615.1 - 8e-71 239.4 6.4 1.6e-30 106.4 4.2 3.0 2 1 1 3 3 3 3 HCO3- transporter family TMEM43 PF07787.12 EGO51615.1 - 0.51 9.7 2.0 0.85 9.0 1.0 1.8 2 0 0 2 2 2 0 Transmembrane protein 43 PHD PF00628.29 EGO51616.1 - 1.8e-10 40.5 2.1 4.3e-10 39.3 2.1 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGO51616.1 - 0.0077 15.8 2.4 0.013 15.1 2.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 EGO51616.1 - 0.14 12.2 1.4 0.37 10.8 1.4 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger C1_1 PF00130.22 EGO51616.1 - 5.2 7.0 6.5 5.2 7.0 0.6 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Glyco_transf_90 PF05686.12 EGO51619.1 - 2e-06 27.0 0.3 0.19 10.6 0.0 3.9 4 0 0 4 4 4 3 Glycosyl transferase family 90 DUF981 PF06168.11 EGO51619.1 - 2 8.3 16.8 1.4 8.8 14.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF981) DHHC PF01529.20 EGO51620.1 - 3.1e-30 105.0 0.8 3.1e-30 105.0 0.8 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Mpv17_PMP22 PF04117.12 EGO51621.1 - 3.7e-26 91.1 2.4 7.4e-26 90.2 2.4 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Lactamase_B PF00753.27 EGO51622.1 - 2e-05 24.7 0.1 3.2e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF777 PF05606.11 EGO51622.1 - 0.13 12.0 0.1 0.22 11.2 0.1 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) Orthopox_A49R PF06489.11 EGO51622.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus A49R protein DUF1451 PF07295.11 EGO51622.1 - 0.19 11.8 0.9 0.41 10.7 0.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain EF-hand_1 PF00036.32 EGO51623.1 - 3.3e-11 41.9 3.3 0.00031 20.1 0.1 4.1 3 0 0 3 3 3 2 EF hand ZZ PF00569.17 EGO51623.1 - 1.9e-09 37.1 7.9 3.9e-09 36.2 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.6 EGO51623.1 - 2.3e-07 31.2 4.5 0.0022 18.4 0.3 4.3 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.6 EGO51623.1 - 9.9e-07 28.2 7.1 0.0005 19.8 0.4 3.6 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EGO51623.1 - 0.00054 19.8 3.4 0.045 13.6 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair C1_2 PF03107.16 EGO51623.1 - 0.0051 17.1 5.9 0.01 16.1 5.9 1.5 1 0 0 1 1 1 1 C1 domain SF3b1 PF08920.10 EGO51623.1 - 0.038 14.5 0.1 0.086 13.4 0.1 1.5 1 0 0 1 1 1 0 Splicing factor 3B subunit 1 EF-hand_5 PF13202.6 EGO51623.1 - 0.44 10.1 6.0 1.3 8.7 0.4 3.6 3 0 0 3 3 3 0 EF hand Cyclin_N PF00134.23 EGO51625.1 - 2.1e-39 134.2 0.6 3.9e-39 133.3 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGO51625.1 - 6.5e-10 39.1 0.0 1.8e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 Cyclin, C-terminal domain UQ_con PF00179.26 EGO51627.1 - 1.3e-47 161.0 0.0 1.5e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO51627.1 - 0.00034 20.3 0.0 0.00044 20.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGO51627.1 - 0.0068 16.3 0.1 0.013 15.4 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 EGO51627.1 - 0.066 13.5 0.0 0.095 13.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain WD40 PF00400.32 EGO51628.1 - 9.6e-07 29.4 19.8 0.0066 17.3 0.2 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 EGO51628.1 - 2.1e-06 27.2 12.4 4.6e-06 26.1 12.4 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 EGO51628.1 - 0.0022 18.3 6.0 0.0054 17.0 6.0 1.6 1 0 0 1 1 1 1 Ring finger domain RWD PF05773.22 EGO51628.1 - 0.074 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 RWD domain Myosin_head PF00063.21 EGO51629.1 - 5.5e-238 791.6 1.7 6.8e-238 791.3 1.7 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGO51629.1 - 1.8e-48 164.7 0.0 3.2e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EGO51629.1 - 2.7e-13 49.3 0.2 5.6e-13 48.3 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGO51629.1 - 3.1e-09 36.6 0.1 7e-09 35.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGO51629.1 - 6.2e-08 32.2 0.0 1.5e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 EGO51629.1 - 0.0092 16.2 0.2 0.023 15.0 0.2 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain IQ PF00612.27 EGO51629.1 - 0.036 13.9 13.2 0.18 11.7 2.3 2.6 1 1 1 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 EGO51629.1 - 0.067 13.5 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 EGO51629.1 - 0.069 12.7 0.3 8 6.0 0.1 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 EGO51629.1 - 0.074 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EGO51629.1 - 0.18 11.7 0.1 0.42 10.5 0.1 1.6 1 0 0 1 1 1 0 NACHT domain NAD_binding_6 PF08030.12 EGO51630.1 - 4.6e-23 82.1 0.0 8e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGO51630.1 - 3.9e-22 78.4 0.0 8.2e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EGO51630.1 - 1.6e-20 73.5 10.2 1.6e-20 73.5 10.2 2.5 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EGO51630.1 - 0.081 13.6 0.0 3.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain UDPGP PF01704.18 EGO51631.1 - 1.7e-56 191.6 0.0 2.5e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EGO51631.1 - 0.095 13.0 0.2 0.29 11.5 0.0 1.8 2 0 0 2 2 2 0 MobA-like NTP transferase domain Fer4_20 PF14691.6 EGO51631.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster BolA PF01722.18 EGO51632.1 - 6.6e-29 100.0 1.7 8.2e-29 99.7 1.7 1.1 1 0 0 1 1 1 1 BolA-like protein AMP-binding PF00501.28 EGO51634.1 - 2.9e-74 250.2 0.0 3.8e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO51634.1 - 2.1e-13 51.0 0.3 6.1e-13 49.6 0.2 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain VID27 PF08553.10 EGO51635.1 - 0.00061 18.9 0.1 0.0011 18.1 0.1 1.3 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain RR_TM4-6 PF06459.12 EGO51635.1 - 0.14 12.0 24.3 0.2 11.4 24.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 EGO51635.1 - 0.54 10.3 7.0 0.56 10.2 7.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SRP-alpha_N PF04086.13 EGO51635.1 - 1.3 8.9 26.0 2 8.3 26.0 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PA26 PF04636.13 EGO51635.1 - 2 7.3 13.2 2.7 6.8 13.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Hid1 PF12722.7 EGO51635.1 - 2.3 6.3 10.8 2.2 6.3 10.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 EGO51635.1 - 3.4 6.3 10.7 3.7 6.2 10.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein G-patch PF01585.23 EGO51635.1 - 5.3 7.0 10.7 0.44 10.5 2.3 3.4 3 1 0 3 3 3 0 G-patch domain Thg1 PF04446.12 EGO51636.1 - 1.9e-55 186.2 0.0 2.9e-55 185.6 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EGO51636.1 - 4.6e-51 172.1 0.2 6.6e-51 171.6 0.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain WD40 PF00400.32 EGO51637.1 - 7.6e-17 61.4 3.4 9.9e-06 26.2 0.2 5.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO51637.1 - 1.6e-10 41.1 0.4 0.00086 19.6 0.0 4.9 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGO51637.1 - 2.2e-05 24.4 0.1 0.1 12.4 0.0 3.5 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF4440 PF14534.6 EGO51637.1 - 0.065 13.6 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) PQQ_2 PF13360.6 EGO51637.1 - 0.067 12.8 0.1 0.57 9.7 0.0 2.4 3 0 0 3 3 3 0 PQQ-like domain RNA_pol_Rpb1_1 PF04997.12 EGO51638.1 - 1.7e-107 359.4 0.0 2.8e-107 358.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EGO51638.1 - 6.6e-100 333.9 0.1 1.2e-99 333.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGO51638.1 - 1.1e-76 256.7 0.0 2.4e-76 255.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EGO51638.1 - 1e-64 217.9 1.7 2e-64 216.9 1.7 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EGO51638.1 - 3.1e-46 157.2 0.0 8.3e-46 155.8 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EGO51638.1 - 4.2e-46 156.3 3.0 1.1e-45 154.9 2.7 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EGO51638.1 - 8.7e-37 125.4 0.1 2.1e-36 124.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EGO51638.1 - 0.1 13.0 200.6 0.041 14.2 5.3 15.3 9 4 7 17 17 17 0 RNA polymerase Rpb1 C-terminal repeat zf-C4pol PF14260.6 EGO51638.1 - 0.27 11.7 1.5 0.74 10.3 1.5 1.7 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Acetyltransf_7 PF13508.7 EGO51639.1 - 1.3e-09 38.4 0.0 2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGO51639.1 - 2.6e-09 37.1 0.0 3.8e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO51639.1 - 6.7e-07 29.6 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGO51639.1 - 2.9e-05 24.0 0.0 7.8e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein HTH_31 PF13560.6 EGO51639.1 - 0.052 13.9 0.0 0.14 12.5 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain Lactamase_B_2 PF12706.7 EGO51639.1 - 0.15 11.6 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Acetyltransf_9 PF13527.7 EGO51639.1 - 0.18 11.9 0.0 0.42 10.7 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain HET PF06985.11 EGO51640.1 - 1.1e-25 90.7 0.2 1.9e-25 89.9 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LMBR1 PF04791.16 EGO51642.1 - 8.1e-18 64.6 23.8 1.8e-16 60.2 19.4 2.3 2 1 0 2 2 2 1 LMBR1-like membrane protein zf-MYND PF01753.18 EGO51644.1 - 1.9 8.6 6.1 3.6 7.8 6.1 1.4 1 0 0 1 1 1 0 MYND finger adh_short_C2 PF13561.6 EGO51646.1 - 2.1e-55 187.8 0.2 3.3e-55 187.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO51646.1 - 1.7e-42 145.1 0.9 2.4e-42 144.6 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO51646.1 - 5.2e-13 49.3 0.3 8.3e-13 48.6 0.3 1.2 1 0 0 1 1 1 1 KR domain Pyr_redox_2 PF07992.14 EGO51646.1 - 0.00013 21.3 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EGO51646.1 - 0.00023 21.6 0.0 0.00042 20.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding GDP_Man_Dehyd PF16363.5 EGO51646.1 - 0.018 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGO51646.1 - 0.062 12.8 0.1 0.13 11.7 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_1 PF00175.21 EGO51647.1 - 1.9e-12 47.8 0.0 3.9e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 EGO51647.1 - 2e-11 44.4 0.0 3.6e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 EGO51647.1 - 2.5e-07 30.9 0.0 4.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGO51647.1 - 0.0008 19.6 0.9 0.011 15.9 0.3 2.6 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 EGO51647.1 - 0.0094 15.9 0.0 0.023 14.6 0.0 1.7 2 0 0 2 2 2 1 Protoglobin TFIIA PF03153.13 EGO51649.1 - 0.31 11.0 20.9 0.36 10.8 20.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zn_clus PF00172.18 EGO51651.1 - 3e-06 27.2 9.4 3e-06 27.2 9.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_B562 PF07361.11 EGO51651.1 - 0.093 13.4 0.0 0.19 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b562 Glyco_hydro_47 PF01532.20 EGO51654.1 - 1.9e-109 366.6 0.0 3.2e-109 365.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pribosyltran PF00156.27 EGO51655.1 - 3.8e-16 59.0 0.0 5e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGO51655.1 - 0.0019 17.7 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Cytochrom_B558a PF05038.13 EGO51656.1 - 2.4 7.7 8.5 0.1 12.2 0.2 2.8 3 1 1 4 4 4 0 Cytochrome Cytochrome b558 alpha-subunit SET PF00856.28 EGO51657.1 - 3.6e-10 40.5 0.9 1.3e-08 35.4 0.1 2.9 2 1 0 2 2 2 1 SET domain Neur_chan_memb PF02932.16 EGO51660.1 - 0.035 14.2 4.0 0.059 13.4 4.0 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 EGO51660.1 - 0.21 10.5 10.4 0.32 9.9 10.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 EGO51660.1 - 0.43 10.5 37.5 0.11 12.5 24.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 EGO51660.1 - 0.71 8.9 12.1 1.1 8.3 12.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein SpoIIP PF07454.11 EGO51660.1 - 1.4 8.3 12.2 2.4 7.6 12.2 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) RR_TM4-6 PF06459.12 EGO51660.1 - 1.7 8.4 10.3 2.6 7.8 10.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spt20 PF12090.8 EGO51660.1 - 1.8 8.1 32.6 4.2 6.9 32.6 1.6 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 EGO51660.1 - 1.8 8.5 15.3 0.016 15.2 6.1 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) NARP1 PF12569.8 EGO51660.1 - 3.4 6.5 11.5 4.8 6.0 11.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.14 EGO51660.1 - 3.9 5.7 10.9 5.3 5.2 10.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Coilin_N PF15862.5 EGO51660.1 - 4 7.2 16.6 7.3 6.4 16.6 1.4 1 0 0 1 1 1 0 Coilin N-terminus GREB1 PF15782.5 EGO51660.1 - 4.1 4.4 16.5 6.9 3.6 16.5 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CobT PF06213.12 EGO51660.1 - 4.5 6.6 18.6 6.6 6.0 18.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sec62 PF03839.16 EGO51660.1 - 6.7 6.2 8.6 12 5.3 8.6 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 SRP-alpha_N PF04086.13 EGO51660.1 - 6.9 6.5 20.8 12 5.7 20.8 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 EGO51660.1 - 7.1 5.3 18.3 11 4.7 18.3 1.2 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 EGO51660.1 - 8.2 5.3 12.9 12 4.8 12.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF3176 PF11374.8 EGO51662.1 - 3.7e-23 81.8 0.8 7.2e-23 80.8 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Arginase PF00491.21 EGO51663.1 - 2.9e-67 227.1 0.4 3.8e-67 226.7 0.4 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EGO51663.1 - 0.064 13.5 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 UPF0489 domain PIP5K PF01504.18 EGO51664.1 - 1.3e-32 113.1 2.2 5.8e-25 88.0 0.1 3.3 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EGO51664.1 - 3.4e-29 101.8 0.1 5.3e-29 101.2 0.1 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EGO51664.1 - 2.3e-15 56.4 13.0 2.3e-15 56.4 13.0 2.2 2 0 0 2 2 2 1 FYVE zinc finger DUF1388 PF07142.12 EGO51664.1 - 0.017 15.0 0.2 0.057 13.4 0.2 1.9 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) YbaB_DNA_bd PF02575.16 EGO51664.1 - 0.36 11.1 6.3 0.48 10.7 1.8 2.5 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family CPSF_A PF03178.15 EGO51665.1 - 2.4e-94 316.3 0.0 4.8e-94 315.3 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 EGO51665.1 - 9e-19 67.5 0.0 3.3e-18 65.6 0.0 1.9 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PAC4 PF16093.5 EGO51669.1 - 0.25 11.6 0.4 0.25 11.6 0.4 1.8 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 CKS PF01111.19 EGO51670.1 - 8.8e-34 115.6 1.6 1.1e-33 115.2 1.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.25 EGO51671.1 - 8.4e-40 134.7 0.1 1.6e-19 69.8 0.0 2.3 2 0 0 2 2 2 2 Bromodomain CD24 PF14984.6 EGO51671.1 - 1.7 8.9 4.8 1.9 8.8 0.1 2.7 2 0 0 2 2 2 0 CD24 protein YfhD PF14151.6 EGO51672.1 - 0.0097 16.0 1.4 0.039 14.1 1.4 2.1 1 0 0 1 1 1 1 YfhD-like protein IF4E PF01652.18 EGO51673.1 - 8.7e-56 188.1 0.1 1.1e-55 187.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E HSP70 PF00012.20 EGO51674.1 - 2.8e-228 759.0 8.6 3.1e-228 758.8 8.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGO51674.1 - 8.9e-18 64.2 0.3 8.4e-17 61.0 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EGO51674.1 - 0.0033 17.2 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EGO51674.1 - 0.031 14.7 4.3 8.9 6.8 0.1 3.7 3 1 0 3 3 3 0 Cell division protein FtsA DDR PF08841.10 EGO51674.1 - 0.062 12.3 1.1 0.19 10.7 0.4 2.1 2 1 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain ERO1 PF04137.15 EGO51675.1 - 1.9e-136 454.9 1.4 1.6e-135 451.9 0.0 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Cytomega_UL84 PF06284.11 EGO51675.1 - 0.046 12.2 1.1 0.079 11.4 1.1 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein HVSL PF09749.9 EGO51676.1 - 2.3e-74 249.8 0.0 2.9e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 EGO51676.1 - 0.00011 22.1 0.0 0.00029 20.8 0.0 1.6 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Cytokin_check_N PF10407.9 EGO51676.1 - 0.067 13.1 0.0 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 Cdc14 phosphatase binding protein N-terminus Pal1 PF08316.11 EGO51678.1 - 1.3e-11 45.4 0.1 2.3e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 Pal1 cell morphology protein Pex2_Pex12 PF04757.14 EGO51679.1 - 5.5e-36 124.3 2.1 8.6e-36 123.6 2.1 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EGO51679.1 - 0.0029 17.7 4.0 0.0057 16.8 4.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGO51679.1 - 0.034 14.2 0.5 0.095 12.7 0.5 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EGO51679.1 - 0.17 11.8 1.4 0.35 10.8 1.4 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 3HCDH_N PF02737.18 EGO51680.1 - 3.4e-31 108.5 0.0 1.1e-30 106.8 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IBN_N PF03810.19 EGO51680.1 - 1.7e-14 53.4 0.1 6.1e-14 51.7 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain 3HCDH PF00725.22 EGO51680.1 - 1e-12 48.4 0.0 2.5e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Xpo1 PF08389.12 EGO51680.1 - 0.00013 22.0 0.1 0.0026 17.8 0.0 2.9 3 0 0 3 3 3 1 Exportin 1-like protein DUF3385 PF11865.8 EGO51680.1 - 0.0022 17.9 0.2 0.29 11.0 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) NAD_binding_2 PF03446.15 EGO51680.1 - 0.0054 16.9 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase SGL PF08450.12 EGO51680.1 - 0.0055 16.3 0.0 0.059 12.9 0.0 2.2 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region 2-Hacid_dh_C PF02826.19 EGO51680.1 - 0.018 14.4 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ldl_recept_b PF00058.17 EGO51680.1 - 0.028 14.9 0.1 9.1 6.9 0.0 4.0 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B MMM1 PF10296.9 EGO51682.1 - 0.00016 20.9 0.0 0.00031 19.9 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 VPS28 PF03997.12 EGO51683.1 - 6.4e-68 228.2 0.0 7.6e-68 227.9 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein Ribonuc_red_sm PF00268.21 EGO51683.1 - 0.12 11.9 0.2 0.19 11.2 0.2 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain Noc2 PF03715.13 EGO51684.1 - 1.3e-130 435.0 0.0 2.6e-130 434.1 0.0 1.5 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 EGO51684.1 - 8.3e-08 30.9 0.3 8.3e-08 30.9 0.3 4.0 2 2 2 4 4 4 2 Nop14-like family DUF726 PF05277.12 EGO51685.1 - 9.8e-119 396.3 2.7 1.6e-118 395.6 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 EGO51685.1 - 0.0008 19.6 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EGO51685.1 - 0.054 14.1 0.7 0.24 12.0 0.1 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family Cutinase PF01083.22 EGO51685.1 - 0.14 12.1 0.0 0.45 10.4 0.0 1.7 2 0 0 2 2 2 0 Cutinase EIAV_GP90 PF00971.18 EGO51685.1 - 0.24 10.0 0.0 0.36 9.5 0.0 1.1 1 0 0 1 1 1 0 EIAV coat protein, gp90 SARAF PF06682.12 EGO51685.1 - 7.2 6.2 5.5 3.5 7.2 0.5 2.5 3 0 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis ApoO PF09769.9 EGO51686.1 - 1.3e-44 151.3 0.2 9.7e-44 148.5 0.0 2.2 2 1 0 2 2 2 1 Apolipoprotein O SBF PF01758.16 EGO51686.1 - 0.071 12.8 0.0 0.46 10.1 0.0 2.0 2 0 0 2 2 2 0 Sodium Bile acid symporter family ABC_sub_bind PF04392.12 EGO51686.1 - 0.11 11.7 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter substrate binding protein Peptidase_M3 PF01432.20 EGO51688.1 - 2.8e-123 412.6 0.0 5e-123 411.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 EGO51688.1 - 0.021 14.5 0.1 0.033 13.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like OST_P2 PF18235.1 EGO51688.1 - 0.21 11.5 0.0 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Oligosaccharyltransferase Peripheral 2 domain WSC PF01822.19 EGO51690.1 - 8e-20 70.8 5.7 1.5e-19 70.0 5.7 1.5 1 0 0 1 1 1 1 WSC domain WLM PF08325.10 EGO51691.1 - 4.1e-65 219.5 1.5 5.4e-65 219.1 0.0 1.9 2 0 0 2 2 2 1 WLM domain zf-RanBP PF00641.18 EGO51691.1 - 0.00054 19.2 2.9 0.00054 19.2 2.9 3.5 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others C1_2 PF03107.16 EGO51691.1 - 0.0097 16.2 6.1 0.18 12.1 0.5 2.6 2 0 0 2 2 2 2 C1 domain zinc_ribbon_15 PF17032.5 EGO51691.1 - 0.039 14.7 2.8 0.62 10.8 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon family zf-Sec23_Sec24 PF04810.15 EGO51691.1 - 0.12 12.4 13.2 1.2 9.3 0.7 3.4 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger DZR PF12773.7 EGO51691.1 - 0.34 11.0 13.6 0.89 9.6 2.7 2.3 2 0 0 2 2 2 0 Double zinc ribbon DUF3243 PF11588.8 EGO51691.1 - 0.42 10.9 2.8 3.3 8.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) TackOD1 PF18551.1 EGO51691.1 - 1.6 8.4 6.4 0.47 10.1 0.5 2.1 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 zf-ribbon_3 PF13248.6 EGO51691.1 - 2.1 7.9 7.8 0.4 10.2 1.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Asp PF00026.23 EGO51692.1 - 3.6e-61 207.3 1.3 4.8e-61 206.9 1.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO51692.1 - 2.5e-11 44.2 1.2 9.9e-06 25.9 0.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO51692.1 - 0.00061 20.4 0.6 0.064 13.9 0.2 3.0 2 1 0 2 2 2 1 Aspartyl protease ANAPC_CDC26 PF10471.9 EGO51693.1 - 5.3e-14 52.8 13.1 5.3e-14 52.8 13.1 6.3 5 1 0 5 5 5 1 Anaphase-promoting complex APC subunit CDC26 Caldesmon PF02029.15 EGO51693.1 - 0.68 8.6 27.0 0.004 16.0 14.6 2.3 2 1 0 2 2 2 0 Caldesmon HATPase_c PF02518.26 EGO51694.1 - 4.6e-29 101.2 0.2 9.3e-29 100.2 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGO51694.1 - 6.5e-23 81.0 0.0 1.3e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGO51694.1 - 2.1e-20 72.5 0.2 6.4e-20 71.0 0.2 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EGO51694.1 - 1.2e-18 67.2 0.0 1.5e-17 63.6 0.3 2.8 4 0 0 4 4 3 1 PAS fold PAS_9 PF13426.7 EGO51694.1 - 1.7e-12 47.5 0.0 1.9e-05 24.9 0.0 3.7 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 EGO51694.1 - 9.9e-09 35.4 0.0 5.7e-05 23.3 0.0 4.1 4 1 0 4 4 4 1 PAS fold PAS PF00989.25 EGO51694.1 - 1.4e-06 28.3 0.0 0.25 11.3 0.0 4.2 5 0 0 5 5 5 2 PAS fold PAS_8 PF13188.7 EGO51694.1 - 1.5e-05 24.9 0.1 0.091 12.8 0.0 3.6 3 0 0 3 3 3 2 PAS domain HATPase_c_3 PF13589.6 EGO51694.1 - 0.00039 20.2 0.0 0.00085 19.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MLTR_LBD PF17765.1 EGO51694.1 - 0.038 14.1 0.0 0.49 10.5 0.0 2.4 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain DUF4172 PF13776.6 EGO51694.1 - 0.17 12.3 0.2 0.53 10.6 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) Aldedh PF00171.22 EGO51695.1 - 1.9e-136 455.2 0.4 2.3e-136 455.0 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family IU_nuc_hydro PF01156.19 EGO51696.1 - 2.1e-79 267.3 0.0 2.4e-79 267.1 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.13 EGO51697.1 - 8.6e-06 25.5 18.0 8.6e-06 25.5 18.0 3.0 2 1 0 3 3 3 1 RED-like protein N-terminal region DUF4148 PF13663.6 EGO51697.1 - 0.039 14.1 1.1 0.1 12.8 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Phage_gp53 PF11246.8 EGO51697.1 - 0.13 11.9 0.4 0.26 10.9 0.4 1.4 1 0 0 1 1 1 0 Base plate wedge protein 53 Lsm_interact PF05391.11 EGO51697.1 - 5.8 6.6 7.1 0.36 10.4 1.0 2.3 2 0 0 2 2 2 0 Lsm interaction motif IMS PF00817.20 EGO51698.1 - 5e-42 143.4 0.0 9.7e-42 142.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 EGO51698.1 - 6.7e-18 64.9 1.6 4.9e-17 62.1 1.6 2.3 1 1 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 EGO51698.1 - 7.5e-15 53.8 11.8 8.8e-06 25.0 0.2 3.7 3 0 0 3 3 3 3 Ubiquitin binding region IMS_C PF11799.8 EGO51698.1 - 1.7e-14 54.5 0.0 3.5e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 EGO51698.1 - 5.9e-07 29.8 0.0 1.4e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 EGO51698.1 - 0.00036 20.7 0.3 0.0023 18.2 0.0 2.6 2 0 0 2 2 2 1 IMS family HHH motif BRCT PF00533.26 EGO51698.1 - 0.0018 18.6 0.0 0.0051 17.2 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain mCpol PF18182.1 EGO51698.1 - 0.0024 18.2 0.0 0.0024 18.2 0.0 2.0 2 0 0 2 2 1 1 minimal CRISPR polymerase domain PTCB-BRCT PF12738.7 EGO51698.1 - 0.0034 17.3 0.0 0.0087 16.0 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain MgtE_N PF03448.17 EGO51698.1 - 0.004 17.7 4.2 6.9 7.3 0.0 4.5 6 0 0 6 6 5 1 MgtE intracellular N domain DUF1805 PF08827.11 EGO51698.1 - 0.047 14.0 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Cdd1 PF11731.8 EGO51698.1 - 0.087 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus FliG_M PF14841.6 EGO51698.1 - 0.13 12.5 4.2 16 5.8 0.1 4.6 5 0 0 5 5 5 0 FliG middle domain LIG3_BRCT PF16759.5 EGO51698.1 - 0.14 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Peptidase_M1_N PF17900.1 EGO51699.1 - 1.5e-05 25.3 0.0 0.053 13.7 0.0 2.6 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain HEAT PF02985.22 EGO51699.1 - 0.15 12.4 0.1 17 6.0 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat SAS4 PF15460.6 EGO51700.1 - 1.8e-33 114.6 0.6 5e-33 113.1 0.6 1.8 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 ABC_tran PF00005.27 EGO51701.1 - 4.5e-35 121.1 0.0 2e-18 67.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGO51701.1 - 3.6e-31 108.8 30.5 6.7e-22 78.4 13.7 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EGO51701.1 - 2.5e-10 40.2 1.7 0.05 13.0 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGO51701.1 - 3.9e-05 23.9 0.2 0.35 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 EGO51701.1 - 5e-05 22.5 3.6 0.071 12.2 0.1 3.4 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_21 PF13304.6 EGO51701.1 - 5.3e-05 23.2 0.2 0.074 12.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGO51701.1 - 5.5e-05 23.1 0.3 0.11 12.4 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EGO51701.1 - 5.5e-05 23.7 0.0 0.016 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGO51701.1 - 0.00012 22.5 0.1 0.72 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 EGO51701.1 - 0.00015 22.1 0.3 0.79 10.2 0.1 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EGO51701.1 - 0.00072 19.6 0.0 1 9.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EGO51701.1 - 0.0013 18.4 4.3 0.021 14.5 0.0 2.9 3 0 0 3 3 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EGO51701.1 - 0.0034 17.6 0.5 0.46 10.8 0.0 3.7 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EGO51701.1 - 0.0063 16.7 0.0 2.5 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EGO51701.1 - 0.0086 16.2 0.1 4.5 7.3 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_24 PF13479.6 EGO51701.1 - 0.011 15.5 0.0 4.3 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGO51701.1 - 0.021 14.8 0.2 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EGO51701.1 - 0.027 14.0 0.1 7.4 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EGO51701.1 - 0.028 13.7 0.7 1.1 8.5 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_15 PF13175.6 EGO51701.1 - 0.028 14.1 0.6 0.073 12.8 0.0 2.0 3 0 0 3 3 2 0 AAA ATPase domain NB-ARC PF00931.22 EGO51701.1 - 0.041 13.1 0.0 2.3 7.3 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 EGO51701.1 - 0.044 13.4 1.2 4.6 6.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EGO51701.1 - 0.046 13.3 0.8 4.7 6.7 0.0 3.0 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGO51701.1 - 0.054 13.4 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EGO51701.1 - 0.055 13.2 1.5 7.1 6.3 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein NACHT PF05729.12 EGO51701.1 - 0.055 13.4 0.3 14 5.5 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA_PrkA PF08298.11 EGO51701.1 - 0.068 12.1 0.0 7.8 5.3 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain PhoH PF02562.16 EGO51701.1 - 0.082 12.4 0.0 12 5.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein K1 PF02960.14 EGO51701.1 - 0.097 12.8 0.1 0.5 10.5 0.1 2.2 1 0 0 1 1 1 0 K1 glycoprotein FtsK_SpoIIIE PF01580.18 EGO51701.1 - 0.13 11.6 0.1 0.29 10.5 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DEAD PF00270.29 EGO51701.1 - 0.13 12.0 0.0 2.8 7.7 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.6 EGO51701.1 - 0.18 11.5 0.2 9.8 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGO51701.1 - 0.18 11.8 0.9 17 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF2474 PF10617.9 EGO51701.1 - 2.6 8.0 6.7 0.14 12.1 0.4 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF2474) VPS9 PF02204.18 EGO51703.1 - 5.6e-20 71.5 0.0 1.3e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 EGO51703.1 - 3.1e-18 65.6 0.7 3.9e-14 52.5 0.0 4.8 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO51703.1 - 4.4e-12 46.4 0.0 0.0015 19.1 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO51703.1 - 4.3e-07 29.7 0.5 0.065 13.8 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 EGO51703.1 - 2.4e-06 28.0 0.0 0.038 14.6 0.0 4.4 3 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EGO51703.1 - 0.0012 19.2 2.2 1.6 9.3 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat PX PF00787.24 EGO51703.1 - 0.0038 17.2 0.1 0.025 14.6 0.0 2.3 2 0 0 2 2 2 1 PX domain YchF-GTPase_C PF06071.13 EGO51705.1 - 9.1e-36 121.9 0.6 2.4e-35 120.6 0.1 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EGO51705.1 - 2.1e-16 60.0 0.0 5.8e-16 58.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO51705.1 - 0.00045 19.8 0.0 0.00083 18.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 EGO51705.1 - 0.0011 19.0 0.0 0.0035 17.4 0.0 1.8 1 0 0 1 1 1 1 TGS domain AAA_18 PF13238.6 EGO51705.1 - 0.016 15.8 0.1 11 6.6 0.0 3.3 3 1 0 3 3 3 0 AAA domain BetaGal_dom3 PF13363.6 EGO51705.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 ABC_tran PF00005.27 EGO51705.1 - 0.35 11.4 1.3 5.7 7.4 0.2 2.3 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 EGO51705.1 - 8.2 6.9 8.2 5.1e+02 1.0 8.2 2.3 1 1 0 1 1 1 0 AAA domain Peptidase_C97 PF05903.14 EGO51706.1 - 5.8e-36 123.6 0.0 7.3e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EGO51706.1 - 0.0012 19.2 0.0 0.0019 18.5 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase 3Beta_HSD PF01073.19 EGO51707.1 - 6e-22 78.0 0.0 3.3e-21 75.5 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGO51707.1 - 1.4e-12 47.6 0.0 3.3e-12 46.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGO51707.1 - 1.2e-11 44.3 0.0 3.1e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EGO51707.1 - 4.5e-09 36.5 0.0 5.1e-08 33.0 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EGO51707.1 - 4.4e-07 30.0 0.7 1.3e-06 28.4 0.7 1.7 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGO51707.1 - 5.2e-05 22.8 0.0 8.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGO51707.1 - 0.0051 15.9 0.0 0.017 14.2 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGO51707.1 - 0.036 13.2 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.18 EGO51707.1 - 0.055 13.7 0.1 0.25 11.6 0.0 1.9 1 1 1 2 2 2 0 TrkA-N domain PRIMA1 PF16101.5 EGO51709.1 - 2.5 8.2 6.2 6 6.9 6.2 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 IBR PF01485.21 EGO51710.1 - 4.7e-11 42.8 27.4 1.8e-08 34.5 7.6 3.9 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 EGO51713.1 - 1.1e-06 28.5 0.5 1.1e-06 28.5 0.5 2.4 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO51713.1 - 7.2e-05 22.6 1.4 7.2e-05 22.6 1.4 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO51713.1 - 8e-05 22.4 4.1 0.0087 15.9 4.1 2.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EGO51713.1 - 0.00043 20.1 13.8 0.021 14.7 0.1 3.9 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO51713.1 - 0.00063 19.7 3.7 0.0008 19.4 1.3 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGO51713.1 - 0.0015 18.6 0.1 0.0015 18.6 0.1 3.1 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING DNA_pol_phi PF04931.13 EGO51713.1 - 0.038 12.1 14.5 0.05 11.7 14.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-C3HC4_2 PF13923.6 EGO51713.1 - 0.044 13.6 0.1 0.044 13.6 0.1 3.4 5 0 0 5 5 4 0 Zinc finger, C3HC4 type (RING finger) Nop14 PF04147.12 EGO51713.1 - 0.09 11.0 8.4 0.13 10.4 8.4 1.2 1 0 0 1 1 1 0 Nop14-like family Prok-RING_1 PF14446.6 EGO51713.1 - 0.15 12.0 9.4 0.41 10.6 8.9 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 BUD22 PF09073.10 EGO51713.1 - 0.44 9.8 5.9 0.6 9.4 5.9 1.2 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 EGO51713.1 - 0.83 9.3 6.6 0.17 11.5 2.4 1.9 2 0 0 2 2 2 0 FAM176 family Pes-10 PF07149.11 EGO51713.1 - 0.84 8.6 11.4 1.3 8.0 11.4 1.2 1 0 0 1 1 1 0 Pes-10 CDC45 PF02724.14 EGO51713.1 - 1.2 7.3 7.5 1.8 6.8 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 EGO51713.1 - 1.6 8.7 6.1 4.1 7.4 6.1 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 EGO51713.1 - 2.5 7.1 17.8 3.9 6.5 17.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.13 EGO51713.1 - 2.7 7.8 10.0 5.1 6.9 10.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region TFIIA PF03153.13 EGO51713.1 - 5.2 6.9 11.4 7.6 6.4 11.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sporozoite_P67 PF05642.11 EGO51713.1 - 6.7 4.7 11.1 9.9 4.1 11.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SEN1_N PF12726.7 EGO51714.1 - 1e-206 688.6 1.8 1.3e-206 688.2 1.8 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 EGO51714.1 - 6.8e-73 245.7 1.1 6.8e-73 245.7 1.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EGO51714.1 - 5.3e-63 212.2 0.0 9.8e-63 211.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGO51714.1 - 1.9e-10 41.2 0.1 1.1e-09 38.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGO51714.1 - 3.9e-09 36.5 0.4 3.8e-05 23.5 0.2 2.6 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 EGO51714.1 - 3e-07 30.3 2.5 9.9e-06 25.3 0.1 2.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 EGO51714.1 - 3.7e-05 23.6 1.1 0.014 15.1 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EGO51714.1 - 0.12 12.7 0.2 1 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGO51714.1 - 0.95 9.8 4.4 9.5 6.6 0.0 3.9 4 0 0 4 4 4 0 AAA ATPase domain HhH-GPD PF00730.25 EGO51715.1 - 1.9e-11 44.4 0.0 4.1e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DNA_methylase PF00145.17 EGO51717.1 - 1.2e-39 136.6 0.0 3.4e-31 108.8 0.0 2.5 2 1 1 3 3 3 2 C-5 cytosine-specific DNA methylase EAF PF09816.9 EGO51718.1 - 1.6e-19 70.1 0.0 4.9e-19 68.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor CBM_6 PF03422.15 EGO51718.1 - 0.11 12.7 0.2 0.37 11.1 0.1 1.9 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) Glyco_hydro_76 PF03663.14 EGO51719.1 - 2.8e-159 530.5 20.4 3.6e-159 530.2 20.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 p450 PF00067.22 EGO51720.1 - 5.7e-65 219.9 0.0 7.4e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sin3a_C PF16879.5 EGO51720.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain of Sin3a protein LigB PF02900.18 EGO51723.1 - 1.2e-37 129.5 0.0 1.3e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase VirB7 PF17413.2 EGO51723.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Outer membrane lipoprotein virB7 TPR_11 PF13414.6 EGO51723.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 TPR repeat Abhydrolase_2 PF02230.16 EGO51724.1 - 1e-62 211.8 0.0 1.2e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EGO51724.1 - 2.7e-08 33.4 0.4 0.00013 21.3 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EGO51724.1 - 7.3e-07 29.1 0.0 2.7e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 EGO51724.1 - 1.5e-06 27.9 0.1 0.00015 21.3 0.0 2.7 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EGO51724.1 - 4.1e-06 27.6 0.1 2.7e-05 24.9 0.1 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO51724.1 - 0.00037 20.2 1.5 5 6.7 0.0 3.4 1 1 2 4 4 4 2 alpha/beta hydrolase fold DLH PF01738.18 EGO51724.1 - 0.00066 19.3 0.1 0.0016 18.0 0.1 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EGO51724.1 - 0.0023 17.8 0.0 2.4 7.9 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold FliD_N PF02465.18 EGO51725.1 - 0.0038 17.9 3.9 1 10.1 0.0 3.5 3 0 0 3 3 3 1 Flagellar hook-associated protein 2 N-terminus IMD PF08397.11 EGO51725.1 - 0.055 12.9 3.1 2.8 7.3 0.5 2.3 2 0 0 2 2 2 0 IRSp53/MIM homology domain Phage_H_T_join PF05521.11 EGO51725.1 - 0.064 13.8 0.1 0.16 12.5 0.1 1.7 1 0 0 1 1 1 0 Phage head-tail joining protein Rab_bind PF16704.5 EGO51725.1 - 0.28 11.2 1.4 1.2 9.3 0.2 2.2 2 0 0 2 2 2 0 Rab binding domain Roughex PF06020.11 EGO51725.1 - 0.31 10.1 4.1 0.57 9.2 4.1 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Atg29_N PF18388.1 EGO51727.1 - 3.6e-22 77.9 0.1 7.1e-22 77.0 0.1 1.5 1 0 0 1 1 1 1 Atg29 N-terminal domain TRI12 PF06609.13 EGO51728.1 - 1.1e-31 109.9 26.5 1.5e-31 109.5 26.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EGO51728.1 - 1e-21 77.3 43.6 1.9e-21 76.4 43.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO51728.1 - 1.1e-09 37.8 32.6 2.2e-09 36.7 11.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Hce2 PF14856.6 EGO51730.1 - 2.1e-16 60.1 0.0 2.8e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Ferric_reduct PF01794.19 EGO51731.1 - 3.4e-20 72.4 2.7 9.9e-20 70.9 2.7 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGO51731.1 - 1.2e-14 54.7 0.0 9.3e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGO51731.1 - 8.7e-13 48.3 0.1 3.4e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 EGO51731.1 - 0.0089 16.7 0.0 0.41 11.3 0.0 2.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain RESP18 PF14948.6 EGO51731.1 - 0.078 13.3 0.2 0.28 11.5 0.2 1.9 1 0 0 1 1 1 0 RESP18 domain DAO PF01266.24 EGO51732.1 - 2.2e-47 162.4 3.3 2.5e-47 162.2 3.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO51732.1 - 0.00037 19.8 0.0 0.13 11.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO51732.1 - 0.0014 19.1 0.0 0.89 10.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGO51732.1 - 0.0051 16.1 0.0 0.0051 16.1 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 EGO51732.1 - 0.027 13.6 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 EGO51732.1 - 0.13 11.1 0.8 0.16 10.7 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 EGO51732.1 - 0.28 11.2 1.2 0.41 10.6 0.0 1.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding adh_short PF00106.25 EGO51733.1 - 1.4e-36 125.8 0.5 2e-36 125.3 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO51733.1 - 3.4e-25 89.0 0.4 6.7e-25 88.0 0.4 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO51733.1 - 0.00015 21.7 1.0 0.00093 19.1 1.0 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO51733.1 - 0.00055 19.5 0.2 0.0032 17.0 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGO51733.1 - 0.0023 17.9 0.4 0.004 17.1 0.4 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Eno-Rase_NADH_b PF12242.8 EGO51733.1 - 0.035 13.9 0.1 0.067 13.0 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CBFD_NFYB_HMF PF00808.23 EGO51735.1 - 7.9e-17 61.3 0.1 1.7e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGO51735.1 - 5.2e-05 23.6 0.4 0.00016 22.0 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EGO51735.1 - 0.01 15.8 0.1 0.029 14.4 0.0 1.8 2 0 0 2 2 2 0 Bromodomain associated TFIID-31kDa PF02291.15 EGO51735.1 - 0.027 14.5 0.0 0.047 13.8 0.0 1.4 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit B12D PF06522.11 EGO51736.1 - 0.047 13.5 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DHHC PF01529.20 EGO51737.1 - 6e-35 120.3 10.5 6e-35 120.3 10.5 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.17 EGO51737.1 - 0.097 12.4 0.1 0.097 12.4 0.1 2.0 2 0 0 2 2 2 0 Yip1 domain TYW3 PF02676.14 EGO51738.1 - 6.7e-72 241.3 1.4 9.4e-72 240.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase TYW3 DUF1690 PF07956.11 EGO51739.1 - 2.7e-42 144.5 11.9 3.1e-42 144.3 11.9 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Allexi_40kDa PF05549.11 EGO51739.1 - 0.012 15.1 3.0 0.014 14.9 3.0 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Spore_III_AB PF09548.10 EGO51739.1 - 0.16 12.1 4.8 0.24 11.5 4.8 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF4407 PF14362.6 EGO51739.1 - 0.17 11.2 6.3 0.18 11.2 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 EGO51739.1 - 0.2 10.2 3.5 0.24 9.9 3.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ALMT PF11744.8 EGO51739.1 - 0.68 8.7 3.1 0.71 8.6 3.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter XRN_M PF17846.1 EGO51739.1 - 1.1 8.2 6.9 1.4 7.8 6.9 1.0 1 0 0 1 1 1 0 Xrn1 helical domain LPP20 PF02169.16 EGO51739.1 - 1.1 9.7 7.3 2 8.8 7.0 1.6 1 1 0 1 1 1 0 LPP20 lipoprotein DUF737 PF05300.11 EGO51739.1 - 1.4 9.2 17.1 2.4 8.4 17.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF737) DUF1640 PF07798.11 EGO51739.1 - 2 8.5 12.5 1.2 9.2 9.7 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1640) FUSC PF04632.12 EGO51739.1 - 3.8 5.9 8.2 4.4 5.7 8.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fungal_trans PF04082.18 EGO51740.1 - 1.1e-09 37.7 0.1 3.1e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO51740.1 - 0.0012 18.9 7.0 0.0022 18.1 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT PF02985.22 EGO51741.1 - 2.6e-15 55.2 12.7 0.0007 19.6 0.0 10.3 12 0 0 12 12 12 3 HEAT repeat HEAT_EZ PF13513.6 EGO51741.1 - 8.2e-13 48.6 9.5 9.1e-09 35.6 0.0 8.2 10 0 0 10 10 10 1 HEAT-like repeat HEAT_2 PF13646.6 EGO51741.1 - 2.8e-08 34.0 16.6 0.62 10.5 0.0 7.6 5 2 3 9 9 9 5 HEAT repeats IBN_N PF03810.19 EGO51741.1 - 5.2e-06 26.3 6.9 7.7e-06 25.7 3.0 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.23 EGO51741.1 - 0.0003 20.7 0.6 18 5.5 0.0 5.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EGO51741.1 - 0.0087 15.6 8.6 1 8.9 0.2 5.3 2 2 4 6 6 6 1 CLASP N terminal DUF3385 PF11865.8 EGO51741.1 - 0.014 15.3 5.2 1.9 8.4 0.0 4.6 3 2 1 4 4 4 0 Domain of unknown function (DUF3385) Cse1 PF08506.10 EGO51741.1 - 0.019 13.8 0.0 0.5 9.1 0.0 2.8 3 0 0 3 3 3 0 Cse1 DUF1548 PF07579.11 EGO51741.1 - 0.21 12.0 0.6 14 6.1 0.0 3.5 3 1 1 4 4 4 0 Domain of Unknown Function (DUF1548) Urb2 PF10441.9 EGO51741.1 - 0.23 11.4 1.6 0.61 10.0 0.0 2.6 2 0 0 2 2 2 0 Urb2/Npa2 family HMGL-like PF00682.19 EGO51742.1 - 1.9e-79 266.9 0.0 3e-79 266.3 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EGO51742.1 - 5.8e-24 84.5 0.0 1.7e-23 82.9 0.0 1.9 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain Ferric_reduct PF01794.19 EGO51743.1 - 2e-23 82.8 6.1 4.7e-23 81.7 6.1 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGO51743.1 - 4e-18 66.0 0.0 1e-15 58.2 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGO51743.1 - 2.1e-08 34.2 0.0 1.4e-05 25.2 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EGO51743.1 - 0.029 15.0 0.0 0.094 13.4 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF3742 PF12553.8 EGO51743.1 - 7.1 6.8 6.8 2.1 8.5 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) Complex1_LYR PF05347.15 EGO51745.1 - 1.1e-24 86.2 1.6 1.5e-24 85.8 1.6 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGO51745.1 - 7.6e-11 42.6 1.4 8.1e-11 42.5 1.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EGO51745.1 - 6.3e-05 23.5 0.2 7.7e-05 23.2 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like VitD-bind_III PF09164.10 EGO51745.1 - 0.049 13.6 0.1 0.075 13.0 0.1 1.2 1 0 0 1 1 1 0 Vitamin D binding protein, domain III DUF1298 PF06974.13 EGO51747.1 - 0.083 12.8 0.0 0.087 12.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) PAPS_reduct PF01507.19 EGO51748.1 - 1.1e-37 129.7 0.0 1.5e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Rhabdo_glycop PF00974.18 EGO51748.1 - 0.16 10.4 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein HAD PF12710.7 EGO51749.1 - 2.5e-18 67.2 0.1 3.5e-18 66.7 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGO51749.1 - 6.6e-14 52.7 0.8 1.8e-13 51.3 0.8 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGO51749.1 - 5.5e-08 32.9 0.8 3.4e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF705 PF05152.12 EGO51749.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) HAD_2 PF13419.6 EGO51749.1 - 0.019 15.1 0.6 5.8 7.0 0.0 2.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TIP39 PF14980.6 EGO51749.1 - 0.091 12.7 0.4 0.24 11.3 0.1 1.9 2 0 0 2 2 2 0 TIP39 peptide Acid_PPase PF12689.7 EGO51749.1 - 0.25 11.2 0.1 0.44 10.4 0.1 1.4 1 0 0 1 1 1 0 Acid Phosphatase GTP_EFTU PF00009.27 EGO51750.1 - 2.7e-54 183.7 0.0 4e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGO51750.1 - 3.6e-41 140.0 0.0 9.7e-41 138.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGO51750.1 - 7e-15 55.2 0.8 7e-15 55.2 0.8 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGO51750.1 - 0.00073 19.6 0.1 0.016 15.3 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EGO51750.1 - 0.1 12.5 0.5 0.32 10.9 0.5 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 FSA_C PF10479.9 EGO51751.1 - 0.16 10.1 0.2 0.17 10.0 0.2 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SLS PF14611.6 EGO51752.1 - 1.9e-39 135.8 0.1 3.3e-39 135.0 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator MAGE PF01454.19 EGO51753.1 - 4.8e-69 232.3 0.0 7.2e-69 231.7 0.0 1.3 1 0 0 1 1 1 1 MAGE family GFRP PF06399.13 EGO51753.1 - 0.0038 17.1 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) MCM6_C PF18263.1 EGO51753.1 - 0.042 14.1 1.8 3.8 7.8 0.3 2.6 2 1 0 2 2 2 0 MCM6 C-terminal winged-helix domain SF3b10 PF07189.11 EGO51754.1 - 8e-39 131.6 0.0 9e-39 131.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) zf-MYND PF01753.18 EGO51755.1 - 0.04 14.0 1.3 0.04 14.0 1.3 3.0 3 0 0 3 3 3 0 MYND finger DUF2470 PF10615.9 EGO51755.1 - 0.052 14.2 1.1 0.63 10.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2470) YwqJ-deaminase PF14431.6 EGO51755.1 - 0.21 11.8 0.1 0.21 11.8 0.1 2.3 3 0 0 3 3 3 0 YwqJ-like deaminase Wbp11 PF09429.10 EGO51755.1 - 0.35 11.3 3.6 0.62 10.5 0.1 2.4 2 0 0 2 2 2 0 WW domain binding protein 11 zf-C6H2 PF15801.5 EGO51755.1 - 0.37 11.1 22.0 0.34 11.2 4.7 3.5 4 0 0 4 4 4 0 zf-MYND-like zinc finger, mRNA-binding THOC7 PF05615.13 EGO51755.1 - 3.4 8.0 6.0 4.1 7.7 0.7 2.7 3 0 0 3 3 3 0 Tho complex subunit 7 DUF1090 PF06476.12 EGO51755.1 - 9.9 6.3 8.8 4.5 7.4 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1090) Septin PF00735.18 EGO51756.1 - 7.4e-36 123.9 0.0 7.5e-13 48.4 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.18 EGO51756.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 EGO51756.1 - 0.026 14.6 0.4 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 Dynamin family G-alpha PF00503.20 EGO51756.1 - 0.036 13.2 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_21 PF13304.6 EGO51756.1 - 0.047 13.5 0.2 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGO51756.1 - 0.052 14.1 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EGO51756.1 - 0.17 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 EGO51756.1 - 0.19 11.9 0.4 0.53 10.4 0.1 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase Nop14 PF04147.12 EGO51756.1 - 0.69 8.1 4.7 1.1 7.4 4.7 1.1 1 0 0 1 1 1 0 Nop14-like family ABC1 PF03109.16 EGO51757.1 - 2e-21 76.4 0.0 3.9e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EGO51757.1 - 0.066 13.1 0.0 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family SUR7 PF06687.12 EGO51759.1 - 3.5e-27 95.4 15.5 4.6e-27 95.0 15.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family 7TM_GPCR_Srd PF10317.9 EGO51759.1 - 0.005 16.1 8.0 0.0071 15.6 8.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd Pox_P21 PF05313.12 EGO51759.1 - 0.91 9.1 4.7 1.5 8.3 4.7 1.3 1 0 0 1 1 1 0 Poxvirus P21 membrane protein bZIP_1 PF00170.21 EGO51761.1 - 2.7e-09 37.0 16.4 5.3e-09 36.1 16.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 EGO51761.1 - 4.1e-06 26.8 6.9 1.4e-05 25.1 0.0 2.4 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_2 PF07716.15 EGO51761.1 - 0.0067 16.5 21.4 0.03 14.4 19.7 2.5 1 1 1 2 2 2 1 Basic region leucine zipper SHE3 PF17078.5 EGO51761.1 - 0.0099 15.6 7.4 0.015 15.0 7.4 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 V_ATPase_I PF01496.19 EGO51761.1 - 0.013 13.5 1.6 0.017 13.1 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF812 PF05667.11 EGO51761.1 - 0.015 14.2 12.9 0.024 13.5 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GvpL_GvpF PF06386.11 EGO51761.1 - 0.027 14.4 9.2 0.051 13.5 9.2 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_Maf PF03131.17 EGO51761.1 - 0.033 14.7 15.4 0.071 13.6 15.4 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor HAP1_N PF04849.13 EGO51761.1 - 0.047 12.9 9.8 0.08 12.1 9.8 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region FlaC_arch PF05377.11 EGO51761.1 - 0.053 13.9 5.0 0.12 12.8 5.0 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF2205 PF10224.9 EGO51761.1 - 0.12 12.3 7.1 0.74 9.9 7.9 1.9 2 0 0 2 2 1 0 Short coiled-coil protein ORF6C PF10552.9 EGO51761.1 - 0.21 11.7 3.4 0.4 10.8 3.4 1.4 1 0 0 1 1 1 0 ORF6C domain PSI_PsaF PF02507.15 EGO51761.1 - 0.25 11.1 0.5 1.1 9.0 0.8 1.8 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III YabA PF06156.13 EGO51761.1 - 0.32 11.6 5.6 0.36 11.5 4.7 1.7 1 1 0 1 1 1 0 Initiation control protein YabA Rootletin PF15035.6 EGO51761.1 - 0.39 10.7 15.5 0.67 10.0 15.5 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TSC22 PF01166.18 EGO51761.1 - 0.64 10.4 5.5 5.9 7.3 3.2 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family UPF0242 PF06785.11 EGO51761.1 - 0.65 10.1 10.6 0.99 9.5 10.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 EGO51761.1 - 0.8 9.0 15.2 0.63 9.4 13.5 1.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding XhlA PF10779.9 EGO51761.1 - 0.92 9.8 4.3 1.8 8.8 4.3 1.4 1 0 0 1 1 1 0 Haemolysin XhlA ADIP PF11559.8 EGO51761.1 - 1.5 8.9 17.4 0.96 9.5 15.7 1.6 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding Sde2_N_Ubi PF13019.6 EGO51761.1 - 1.6 8.5 9.1 3.1 7.6 9.1 1.4 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain DUF3584 PF12128.8 EGO51761.1 - 2 5.8 16.2 2.6 5.5 16.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ECM1 PF05782.11 EGO51761.1 - 3.9 6.3 10.3 5.5 5.8 9.7 1.4 1 1 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Tho2 PF11262.8 EGO51761.1 - 5.7 6.1 9.0 9 5.4 9.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LCD1 PF09798.9 EGO51761.1 - 7.9 4.9 8.0 10 4.5 8.0 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein CDP-OH_P_transf PF01066.21 EGO51762.1 - 2.1e-17 63.7 0.1 2.1e-17 63.7 0.1 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3592 PF12158.8 EGO51762.1 - 0.2 11.7 3.2 10 6.1 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3592) DUF3267 PF11667.8 EGO51762.1 - 2.3 8.6 10.1 0.22 11.8 0.6 3.2 3 0 0 3 3 3 0 Putative zincin peptidase Adaptin_N PF01602.20 EGO51763.1 - 5.4e-113 378.3 0.4 6.8e-113 378.0 0.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EGO51763.1 - 1.7e-55 187.3 3.0 3.5e-55 186.3 3.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EGO51763.1 - 7.2e-36 122.8 0.2 1.9e-35 121.4 0.2 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EGO51763.1 - 3.1e-17 62.7 4.5 4.1e-12 46.3 0.1 5.5 3 1 2 5 5 5 1 HEAT repeats Cnd1 PF12717.7 EGO51763.1 - 1.1e-06 28.8 10.9 0.033 14.2 0.1 5.1 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 EGO51763.1 - 0.00068 20.1 0.0 1.5 9.7 0.0 4.4 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat CLASP_N PF12348.8 EGO51763.1 - 0.017 14.7 4.9 0.066 12.8 0.1 3.1 4 0 0 4 4 4 0 CLASP N terminal RTP1_C1 PF10363.9 EGO51763.1 - 0.039 14.1 0.3 4 7.7 0.0 3.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EGO51763.1 - 0.044 14.1 6.9 2.2 8.7 0.2 5.4 5 0 0 5 5 5 0 HEAT repeat Coatomer_b_Cpla PF14806.6 EGO51763.1 - 0.047 13.7 0.0 0.25 11.3 0.0 2.2 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform DUF5508 PF17621.2 EGO51763.1 - 0.069 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5508) DUF5010 PF16402.5 EGO51763.1 - 0.087 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) HEAT_EZ PF13513.6 EGO51763.1 - 7.1 7.2 7.0 1.3 9.6 0.3 3.3 3 1 1 4 4 4 0 HEAT-like repeat UPF0016 PF01169.19 EGO51765.1 - 6e-43 145.1 23.8 9.8e-23 80.3 8.5 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 LysE PF01810.18 EGO51765.1 - 2.9 7.3 15.7 0.21 11.0 2.9 2.3 2 0 0 2 2 2 0 LysE type translocator EI24 PF07264.11 EGO51766.1 - 5.6e-13 49.5 6.2 1.2e-12 48.4 6.2 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) ATP-sulfurylase PF01747.17 EGO51769.1 - 2.7e-87 291.7 0.0 3.8e-87 291.2 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 EGO51769.1 - 2.1e-57 193.5 0.0 3.1e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 EGO51769.1 - 4.8e-53 179.1 0.0 7.3e-53 178.5 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.10 EGO51769.1 - 0.0019 17.7 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 EGO51769.1 - 0.026 15.1 0.0 0.052 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGO51769.1 - 0.075 13.2 0.1 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain MBA1 PF07961.11 EGO51771.1 - 1.5e-08 34.1 0.1 1.9e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.15 EGO51771.1 - 0.00096 19.3 0.1 0.0016 18.5 0.1 1.4 1 0 0 1 1 1 1 Tim44-like domain SUI1 PF01253.22 EGO51773.1 - 2.5e-27 95.2 2.4 3.5e-27 94.7 2.4 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF2575 PF10837.8 EGO51773.1 - 0.097 13.0 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) AdoMet_MTase PF07757.13 EGO51774.1 - 8.5e-40 135.6 0.0 1.3e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 EGO51774.1 - 0.0071 16.3 0.0 0.071 13.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO51774.1 - 0.085 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Dioxygenase_C PF00775.21 EGO51775.1 - 2.8e-41 140.9 0.0 4.4e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EGO51775.1 - 1.3e-30 105.1 0.0 2.3e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EGO51775.1 - 0.027 14.7 0.0 0.13 12.6 0.0 2.1 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain TRP PF06011.12 EGO51776.1 - 5.3e-93 312.1 14.4 7.1e-93 311.6 14.4 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EGO51776.1 - 2.7e-19 69.9 0.0 7.9e-19 68.4 0.0 1.7 2 0 0 2 2 2 1 ML-like domain SSF PF00474.17 EGO51777.1 - 7.5e-07 28.3 27.9 3.8e-06 26.0 27.9 2.0 1 1 0 1 1 1 1 Sodium:solute symporter family RRM_1 PF00076.22 EGO51779.1 - 1.4e-19 69.7 0.0 1.5e-09 37.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CIA30 PF08547.12 EGO51780.1 - 9.8e-47 158.9 0.0 1.6e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Macoilin PF09726.9 EGO51781.1 - 0.072 11.7 17.5 0.086 11.4 17.5 1.3 1 0 0 1 1 1 0 Macoilin family DUF2407_C PF13373.6 EGO51781.1 - 0.41 10.8 0.0 0.41 10.8 0.0 2.8 2 1 0 2 2 2 0 DUF2407 C-terminal domain JmjC PF02373.22 EGO51782.1 - 9.6e-17 61.5 0.0 9.6e-17 61.5 0.0 3.1 3 1 0 3 3 3 1 JmjC domain, hydroxylase SET PF00856.28 EGO51782.1 - 5.3e-05 23.7 0.0 5.3e-05 23.7 0.0 2.8 2 2 0 2 2 2 1 SET domain RRM_1 PF00076.22 EGO51783.1 - 0.082 12.7 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2730 PF10805.8 EGO51784.1 - 0.0052 16.9 8.2 0.08 13.0 1.0 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF2730) Spc7 PF08317.11 EGO51784.1 - 0.067 12.1 21.8 0.29 10.0 2.3 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein ATG16 PF08614.11 EGO51784.1 - 0.1 12.8 27.0 0.32 11.2 2.2 3.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) CENP-K PF11802.8 EGO51784.1 - 0.27 10.8 10.9 0.41 10.2 10.9 1.2 1 0 0 1 1 1 0 Centromere-associated protein K Cep57_MT_bd PF06657.13 EGO51784.1 - 0.39 11.2 19.5 1 9.9 6.6 3.8 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 TMF_TATA_bd PF12325.8 EGO51784.1 - 0.46 10.7 22.0 0.25 11.6 8.2 3.4 4 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 EGO51784.1 - 0.72 10.3 19.1 0.51 10.8 16.8 1.9 2 1 0 2 2 2 0 Fez1 Seryl_tRNA_N PF02403.22 EGO51784.1 - 0.82 9.9 17.9 1.4 9.2 6.8 2.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HAUS-augmin3 PF14932.6 EGO51784.1 - 1.1 8.7 18.1 0.12 11.9 9.3 2.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 FlaC_arch PF05377.11 EGO51784.1 - 1.2 9.6 5.1 4.9 7.6 0.5 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 EGO51784.1 - 1.4 9.3 9.3 2.8 8.3 1.5 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LPP PF04728.13 EGO51784.1 - 2.1 8.8 9.1 33 5.0 4.5 4.2 3 1 0 3 3 3 0 Lipoprotein leucine-zipper SlyX PF04102.12 EGO51784.1 - 3.7 8.2 17.4 0.58 10.8 4.3 3.6 2 1 1 4 4 4 0 SlyX rhaM PF05336.13 EGO51785.1 - 5.7e-37 126.1 1.0 7.3e-37 125.7 1.0 1.1 1 0 0 1 1 1 1 L-rhamnose mutarotase Thioredoxin PF00085.20 EGO51786.1 - 7.6e-05 22.6 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EGO51786.1 - 0.0063 16.2 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 EGO51786.1 - 0.02 15.3 0.0 0.2 12.1 0.0 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain DUF953 PF06110.11 EGO51786.1 - 0.043 13.4 0.1 0.49 10.0 0.1 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) MFS_1 PF07690.16 EGO51787.1 - 2.2e-43 148.5 22.7 4.9e-32 111.2 2.6 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO51787.1 - 1.3e-16 60.5 2.6 1.3e-16 60.5 2.6 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter ELP6 PF09807.9 EGO51788.1 - 1.9e-11 43.9 1.1 3e-07 30.1 0.2 2.2 2 0 0 2 2 2 2 Elongation complex protein 6 ATPase_2 PF01637.18 EGO51788.1 - 0.001 19.0 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF4805 PF16063.5 EGO51788.1 - 0.032 13.6 1.5 0.056 12.8 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Acetyltransf_6 PF13480.7 EGO51788.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L37e PF01907.19 EGO51789.1 - 4.3e-21 74.8 16.1 1e-12 48.0 2.4 2.3 2 0 0 2 2 2 2 Ribosomal protein L37e FYVE PF01363.21 EGO51789.1 - 0.036 14.2 1.4 0.064 13.4 1.4 1.4 1 0 0 1 1 1 0 FYVE zinc finger DUF2845 PF11006.8 EGO51789.1 - 0.052 13.7 0.5 0.1 12.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2845) Ribosomal_S14 PF00253.21 EGO51789.1 - 0.36 10.6 6.4 5.8 6.8 0.4 2.6 2 1 0 2 2 2 0 Ribosomal protein S14p/S29e Rubredoxin_2 PF18073.1 EGO51789.1 - 0.42 10.4 2.7 13 5.6 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain tRNA-synt_1 PF00133.22 EGO51790.1 - 4.8e-242 804.5 0.2 5.9e-241 800.9 0.2 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGO51790.1 - 1.7e-36 125.5 0.0 5.5e-36 123.8 0.0 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGO51790.1 - 1.4e-15 56.9 0.2 1.5e-05 23.9 0.1 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EGO51790.1 - 2.7e-13 49.9 0.5 2.3e-08 33.8 0.0 2.8 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EGO51790.1 - 0.00043 19.7 0.0 0.029 13.7 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.9 EGO51790.1 - 0.001 19.3 6.0 0.001 19.3 6.0 2.4 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1b PF00579.25 EGO51790.1 - 0.31 10.3 2.0 3.2 7.0 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) zf-RING_2 PF13639.6 EGO51791.1 - 3.5e-13 49.7 5.3 5.4e-13 49.0 5.3 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 EGO51791.1 - 7.9e-11 41.8 0.0 1.9e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 EGO51791.1 - 7.1e-10 38.6 3.9 1.1e-09 38.0 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO51791.1 - 1.8e-09 37.3 3.4 2.8e-09 36.7 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGO51791.1 - 3.6e-09 36.2 2.5 3.6e-09 36.2 2.5 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 EGO51791.1 - 5.9e-08 32.9 5.6 1.7e-07 31.4 5.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGO51791.1 - 4.4e-07 29.8 1.5 1.1e-06 28.6 0.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGO51791.1 - 8.3e-07 28.9 2.5 1.3e-06 28.3 2.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGO51791.1 - 1.7e-05 24.6 2.9 2.6e-05 24.0 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGO51791.1 - 0.0018 18.3 2.3 0.0052 16.8 2.3 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGO51791.1 - 0.015 14.9 2.3 0.027 14.1 2.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EGO51791.1 - 0.022 14.6 2.5 0.038 13.8 2.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EGO51791.1 - 0.032 14.4 2.6 0.081 13.1 2.6 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 EGO51791.1 - 0.058 13.6 3.9 0.11 12.6 3.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 EGO51791.1 - 0.4 10.8 5.3 0.63 10.2 4.3 1.9 1 1 1 2 2 2 0 RING-variant domain zf-Nse PF11789.8 EGO51791.1 - 0.48 10.3 2.5 0.89 9.4 2.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 EGO51791.1 - 0.7 9.8 2.2 1.3 9.0 2.2 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 EGO51791.1 - 0.79 10.1 3.0 1.4 9.3 3.0 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EGO51791.1 - 1 9.2 3.0 1.9 8.4 3.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4083 PF13314.6 EGO51791.1 - 5.1 7.1 4.8 11 6.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) ANAPC5 PF12862.7 EGO51792.1 - 1.4e-31 108.4 3.3 1.4e-31 108.4 3.3 3.1 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 EGO51792.1 - 7.7e-07 29.3 17.6 0.03 14.6 0.3 5.9 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGO51792.1 - 0.00022 21.0 4.6 1.4 8.9 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGO51792.1 - 0.0076 17.0 24.2 3.7 8.6 0.0 8.0 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGO51792.1 - 0.11 12.9 1.4 11 6.4 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGO51792.1 - 0.41 10.8 5.9 12 6.2 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGO51792.1 - 1.1 9.8 19.1 6.9 7.3 1.4 5.7 4 2 2 6 6 6 0 Tetratricopeptide repeat COX6A PF02046.15 EGO51793.1 - 1.2e-52 177.2 1.3 1.4e-52 176.9 1.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos PF03372.23 EGO51794.1 - 3.7e-13 49.5 0.0 6.1e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 EGO51794.1 - 2e-05 24.6 1.8 4.9e-05 23.3 1.8 1.7 1 0 0 1 1 1 1 GRF zinc finger HMG_box PF00505.19 EGO51795.1 - 4.7e-18 65.4 0.0 7.4e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box MAT1-1-2 PF17043.5 EGO51796.1 - 3.5e-36 124.4 0.0 6e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Mating type protein 1-1-2 of unknown function MATalpha_HMGbox PF04769.12 EGO51797.1 - 8.5e-76 253.7 0.0 1.4e-75 253.0 0.0 1.3 2 0 0 2 2 2 1 Mating-type protein MAT alpha 1 HMG-box ANTH PF07651.16 EGO51799.1 - 3.9e-83 278.6 0.0 3.9e-83 278.6 0.0 2.9 3 1 0 4 4 4 1 ANTH domain I_LWEQ PF01608.17 EGO51799.1 - 3.9e-54 183.0 10.0 3.9e-54 183.0 10.0 6.6 4 2 2 7 7 7 2 I/LWEQ domain FAA_hydro_N_2 PF18288.1 EGO51799.1 - 7.1 7.1 10.5 0.29 11.6 0.6 4.0 2 1 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 Autophagy_N PF03986.13 EGO51800.1 - 1.9e-44 150.9 0.0 3.4e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 EGO51800.1 - 1.2e-15 56.7 0.5 2.3e-15 55.8 0.5 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 EGO51800.1 - 1.6e-13 51.0 0.2 3.1e-13 50.1 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain QLQ PF08880.11 EGO51800.1 - 0.26 11.1 0.3 0.57 10.0 0.3 1.5 1 0 0 1 1 1 0 QLQ zf-CCCH PF00642.24 EGO51801.1 - 1.7e-08 34.2 2.1 3.9e-08 33.0 2.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 EGO51801.1 - 1.2e-06 28.3 5.9 2.1e-06 27.6 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGO51801.1 - 2.3e-06 27.3 5.1 4.3e-06 26.5 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO51801.1 - 2.8e-06 27.1 3.7 5.3e-06 26.2 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO51801.1 - 1.1e-05 25.2 5.5 2e-05 24.3 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO51801.1 - 1.5e-05 25.2 5.0 2.7e-05 24.4 5.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 EGO51801.1 - 2.1e-05 24.4 6.2 4.1e-05 23.5 6.2 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_UBOX PF13445.6 EGO51801.1 - 2.9e-05 24.0 5.0 5.6e-05 23.1 5.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 EGO51801.1 - 3.5e-05 23.8 1.9 3.5e-05 23.8 1.9 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-CCCH_4 PF18044.1 EGO51801.1 - 0.00023 20.9 2.6 0.00023 20.9 2.6 1.9 2 0 0 2 2 1 1 CCCH-type zinc finger DUF4278 PF14105.6 EGO51801.1 - 0.054 13.9 0.1 0.14 12.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4278) zf-C3HC4_4 PF15227.6 EGO51801.1 - 0.06 13.5 6.8 0.15 12.3 6.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 EGO51801.1 - 0.094 13.2 3.6 0.2 12.2 3.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Prok-RING_4 PF14447.6 EGO51801.1 - 0.099 12.5 4.7 0.19 11.6 4.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGO51801.1 - 0.15 12.4 2.0 0.3 11.4 2.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Mcp5_PH PF12814.7 EGO51802.1 - 1.2e-45 154.6 0.0 2.3e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 EGO51802.1 - 4.4e-05 24.0 0.0 0.00011 22.7 0.0 1.7 1 0 0 1 1 1 1 PH domain DNA_pol_B PF00136.21 EGO51803.1 - 7.6e-102 341.4 0.0 1.2e-101 340.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGO51803.1 - 1.7e-19 70.1 0.1 1.4e-10 40.9 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EGO51803.1 - 3.4e-17 62.7 0.5 3.4e-17 62.7 0.5 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Slu7 PF11708.8 EGO51804.1 - 1.5e-69 234.8 14.2 1.5e-69 234.8 14.2 1.9 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.23 EGO51804.1 - 0.0015 18.5 4.8 0.0028 17.7 4.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGO51804.1 - 0.0037 17.0 0.1 0.0067 16.1 0.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGO51804.1 - 0.2 11.5 3.8 0.47 10.3 3.8 1.6 1 0 0 1 1 1 0 Zinc knuckle S4 PF01479.25 EGO51805.1 - 1.1e-11 44.2 1.1 1.1e-11 44.2 1.1 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EGO51805.1 - 1.6e-05 25.7 0.1 3e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 EGO51805.1 - 0.063 13.4 0.5 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Ribosomal_L21e PF01157.18 EGO51806.1 - 8e-47 157.3 6.1 1.3e-46 156.6 6.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e DUF5486 PF17588.2 EGO51806.1 - 0.15 12.0 1.6 2.4 8.1 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5486) MMM1 PF10296.9 EGO51807.1 - 4.8e-06 25.9 6.4 6.3e-06 25.5 0.1 2.5 2 1 0 3 3 3 2 Maintenance of mitochondrial morphology protein 1 ISN1 PF06437.11 EGO51808.1 - 3.5e-185 615.8 0.0 4.3e-185 615.4 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase TMCO5 PF14992.6 EGO51809.1 - 0.046 13.3 1.0 0.093 12.3 1.0 1.4 1 0 0 1 1 1 0 TMCO5 family Prefoldin PF02996.17 EGO51809.1 - 0.15 11.9 2.6 0.26 11.2 2.6 1.3 1 0 0 1 1 1 0 Prefoldin subunit DUF4482 PF14818.6 EGO51809.1 - 4.5 8.1 13.7 0.047 14.6 4.0 2.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4482) RRXRR PF14239.6 EGO51813.1 - 0.0071 16.2 0.0 0.0089 15.9 0.0 1.2 1 0 0 1 1 1 1 RRXRR protein Pkinase PF00069.25 EGO51814.1 - 5.2e-49 167.0 0.0 6.9e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO51814.1 - 2.6e-25 89.2 0.3 1.4e-24 86.8 0.3 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO51814.1 - 0.00073 18.9 0.3 0.02 14.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGO51814.1 - 0.0016 17.3 0.8 0.003 16.4 0.2 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGO51814.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGO51814.1 - 0.025 14.2 0.6 1.5 8.4 0.1 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 IBN_N PF03810.19 EGO51815.1 - 5.5e-11 42.2 5.8 5.2e-10 39.1 0.2 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 EGO51815.1 - 6.1e-08 31.9 0.0 1.5e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 EGO51815.1 - 1.1e-05 25.6 5.9 0.00053 20.1 0.0 4.6 5 0 0 5 5 5 1 Exportin 1-like protein MOR2-PAG1_C PF14225.6 EGO51815.1 - 0.013 15.4 0.2 0.29 11.0 0.1 2.9 2 0 0 2 2 2 0 Cell morphogenesis C-terminal RIX1 PF08167.12 EGO51815.1 - 0.017 14.9 0.3 0.81 9.4 0.0 3.5 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 EGO51815.1 - 0.033 14.8 0.9 7.7 7.2 0.1 3.8 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EGO51815.1 - 0.08 13.1 0.8 3.3 7.9 0.1 3.2 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Importin_rep_6 PF18829.1 EGO51815.1 - 6.8 6.9 6.6 1.1 9.4 0.1 3.2 4 0 0 4 4 4 0 Importin repeat 6 IMS PF00817.20 EGO51819.1 - 1.6e-44 151.5 0.0 3.2e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EGO51819.1 - 5.8e-15 56.0 0.0 1.8e-14 54.5 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 EGO51819.1 - 4.7e-13 48.5 1.9 1.1e-12 47.3 1.9 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 EGO51819.1 - 0.00018 21.6 0.0 0.00042 20.5 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif DHHC PF01529.20 EGO51820.1 - 3.7e-28 98.3 5.4 3.7e-28 98.3 5.4 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Med19 PF10278.9 EGO51820.1 - 0.32 10.9 4.5 13 5.7 4.1 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 MARVEL PF01284.23 EGO51820.1 - 0.61 10.1 9.7 1.5 8.8 2.5 2.4 2 0 0 2 2 2 0 Membrane-associating domain Claudin_2 PF13903.6 EGO51820.1 - 0.87 9.3 5.8 0.12 12.1 0.4 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction 7tm_1 PF00001.21 EGO51820.1 - 0.92 8.8 6.7 0.27 10.5 0.2 2.5 2 1 1 3 3 3 0 7 transmembrane receptor (rhodopsin family) DUF1218 PF06749.12 EGO51820.1 - 4.5 7.9 7.7 1.9 9.1 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) zf-B_box PF00643.24 EGO51821.1 - 0.031 14.4 4.4 0.71 10.1 2.7 2.2 2 0 0 2 2 2 0 B-box zinc finger FYVE_2 PF02318.16 EGO51821.1 - 1.2 9.3 6.9 3 8.1 1.9 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger Actino_peptide PF14408.6 EGO51821.1 - 8.1 6.6 9.4 7 6.8 7.4 1.9 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes SET PF00856.28 EGO51822.1 - 7.3e-13 49.3 0.6 3.5e-12 47.0 0.6 2.2 1 1 0 1 1 1 1 SET domain AWS PF17907.1 EGO51822.1 - 2.6e-06 27.4 6.9 5.5e-06 26.3 6.9 1.5 1 0 0 1 1 1 1 AWS domain SR-25 PF10500.9 EGO51823.1 - 0.41 10.2 10.9 0.82 9.2 10.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 EGO51823.1 - 2.5 8.0 20.1 2.9 7.8 20.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 EGO51823.1 - 4.4 6.8 11.2 5.5 6.5 11.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Roughex PF06020.11 EGO51823.1 - 5.2 6.1 8.4 7.1 5.6 8.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Apidaecin PF00807.17 EGO51824.1 - 0.052 13.7 0.6 0.11 12.6 0.6 1.6 1 0 0 1 1 1 0 Apidaecin Zn_clus PF00172.18 EGO51824.1 - 0.51 10.5 9.4 1.2 9.3 9.4 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PADR1 PF08063.12 EGO51824.1 - 0.73 9.7 3.7 1.8 8.4 3.7 1.6 1 0 0 1 1 1 0 PADR1 (NUC008) domain LSM PF01423.22 EGO51825.1 - 4e-20 71.3 0.1 5e-20 71.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EGO51825.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Pan3_PK PF18101.1 EGO51826.1 - 2e-50 170.3 0.4 3.2e-50 169.7 0.4 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EGO51826.1 - 0.00028 20.4 0.0 0.00064 19.2 0.0 1.5 1 1 0 2 2 2 1 Protein kinase domain UBA_4 PF14555.6 EGO51827.1 - 6.9e-11 41.8 0.0 1.4e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EGO51827.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 UBX domain SUB1_ProdP9 PF18213.1 EGO51827.1 - 0.022 14.6 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 Methyltransf_24 PF13578.6 EGO51827.1 - 0.046 14.8 0.7 3.9 8.6 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain GAT PF03127.14 EGO51828.1 - 7.9e-19 67.8 0.9 2.4e-18 66.2 0.2 2.2 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 EGO51828.1 - 0.00081 19.2 0.2 0.0095 15.8 0.0 2.3 2 1 0 2 2 2 1 VHS domain Serglycin PF04360.12 EGO51828.1 - 0.24 11.3 23.4 0.063 13.2 3.3 3.6 3 0 0 3 3 3 0 Serglycin F-box-like PF12937.7 EGO51829.1 - 1.6e-07 31.1 0.1 6.1e-07 29.2 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO51829.1 - 8e-05 22.4 1.4 0.00045 20.0 0.5 2.5 2 0 0 2 2 2 1 F-box domain Zn_clus PF00172.18 EGO51830.1 - 0.02 15.0 1.9 0.032 14.4 1.9 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.6 EGO51833.1 - 3.1e-17 62.9 0.0 4.2e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO51833.1 - 4.6e-14 52.9 0.0 1.9e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO51833.1 - 6.3e-14 52.4 0.0 1.8e-13 51.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO51833.1 - 3.2e-13 49.7 0.0 4.9e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO51833.1 - 4.1e-13 49.9 0.0 8.1e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO51833.1 - 5.6e-07 29.1 0.0 1.6e-06 27.6 0.0 1.7 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EGO51833.1 - 8.8e-05 22.5 0.0 0.00016 21.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EGO51833.1 - 0.00056 19.3 0.0 0.0011 18.3 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.11 EGO51833.1 - 0.028 14.1 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DREV PF05219.12 EGO51833.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 EGO51833.1 - 0.15 11.6 0.1 0.31 10.6 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain His_Phos_1 PF00300.22 EGO51834.1 - 1.2e-36 126.3 2.1 1.3e-34 119.6 2.1 2.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3716 PF12511.8 EGO51835.1 - 2.4e-08 33.9 10.2 5.1e-08 32.8 10.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Mucin PF01456.17 EGO51835.1 - 0.51 10.3 14.4 1.5 8.8 14.4 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein UCH PF00443.29 EGO51838.1 - 1e-48 166.1 0.0 1.5e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO51838.1 - 4.2e-15 56.2 3.0 1.4e-14 54.4 3.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EGO51838.1 - 2.1e-12 46.6 0.1 5.7e-12 45.2 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 EGO51838.1 - 0.098 12.6 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain Peptidase_C98 PF15499.6 EGO51838.1 - 0.13 11.7 0.0 0.74 9.2 0.0 2.2 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ARPC4 PF05856.12 EGO51839.1 - 1e-80 269.2 4.0 1.1e-80 269.1 4.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RRM_1 PF00076.22 EGO51840.1 - 1.1e-05 25.1 0.0 2.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EGO51840.1 - 0.032 14.3 0.0 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 DUF4834 PF16118.5 EGO51840.1 - 1.5 9.9 8.6 3 8.9 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Mito_carr PF00153.27 EGO51841.1 - 1.3e-73 243.0 2.7 1.8e-24 85.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HP_OMP PF01856.17 EGO51841.1 - 0.043 13.9 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Helicobacter outer membrane protein Serine_protease PF18405.1 EGO51841.1 - 0.22 10.7 3.7 4.7 6.3 0.1 3.2 1 1 1 3 3 3 0 Gammaproteobacterial serine protease PRP21_like_P PF12230.8 EGO51842.1 - 3.2e-56 190.6 8.4 1.2e-55 188.8 8.4 1.9 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EGO51842.1 - 1.4e-34 117.8 0.5 6.4e-16 58.1 0.0 2.6 2 0 0 2 2 2 2 Surp module PX PF00787.24 EGO51842.1 - 2e-24 85.7 0.4 5.2e-24 84.4 0.0 1.9 2 0 0 2 2 2 1 PX domain zf_UBZ PF18439.1 EGO51842.1 - 0.002 17.6 0.3 0.0039 16.7 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger zf-C4H2 PF10146.9 EGO51842.1 - 0.71 10.1 9.5 0.48 10.7 3.0 2.5 2 0 0 2 2 2 0 Zinc finger-containing protein Taxilin PF09728.9 EGO51842.1 - 2.1 7.4 8.6 0.031 13.5 1.1 1.7 2 0 0 2 2 2 0 Myosin-like coiled-coil protein PMT PF02366.18 EGO51843.1 - 1.1e-78 264.3 13.1 1.1e-78 264.3 13.1 2.3 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EGO51843.1 - 2.8e-68 229.4 16.2 2.8e-68 229.4 16.2 1.9 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGO51843.1 - 9.5e-49 165.8 0.0 9.5e-49 165.8 0.0 2.7 2 1 0 2 2 2 1 MIR domain Apolipoprotein PF01442.18 EGO51843.1 - 1.4e-08 34.8 52.9 7.1e-06 26.0 35.1 2.3 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain YtxH PF12732.7 EGO51843.1 - 6.8e-07 29.7 51.0 0.062 13.8 16.3 4.9 1 1 2 3 3 3 2 YtxH-like protein DUF883 PF05957.13 EGO51843.1 - 9.3e-05 23.0 37.2 0.019 15.5 4.9 3.8 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) SecA_SW PF07516.13 EGO51843.1 - 0.0052 16.9 11.0 0.72 9.9 0.0 2.4 1 1 1 2 2 2 1 SecA Wing and Scaffold domain ApoLp-III PF07464.11 EGO51843.1 - 0.13 12.3 54.1 0.077 13.1 27.8 2.5 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF812 PF05667.11 EGO51843.1 - 1.4 7.7 42.4 2 7.2 42.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) LEA_4 PF02987.16 EGO51843.1 - 5.2 7.2 52.5 0.46 10.6 12.3 5.2 1 1 2 4 4 4 0 Late embryogenesis abundant protein DUF948 PF06103.11 EGO51843.1 - 7 7.0 31.0 3.9 7.8 5.8 4.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4316 PF14195.6 EGO51843.1 - 8.3 6.3 7.0 2.1 8.2 1.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) GRDP-like PF07173.12 EGO51845.1 - 1.6e-20 74.2 3.0 1.4e-14 54.9 0.1 3.3 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like DUF1045 PF06299.12 EGO51845.1 - 0.038 14.0 0.1 0.071 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) Feld-I_B PF09252.10 EGO51847.1 - 0.039 13.9 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 Allergen Fel d I-B chain TerB_N PF13208.6 EGO51848.1 - 0.17 11.6 3.4 0.58 9.8 3.4 1.8 1 0 0 1 1 1 0 TerB N-terminal domain T4_Rnl2_C PF18043.1 EGO51857.1 - 0.036 14.2 0.1 0.065 13.4 0.1 1.4 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal Mt_ATP_synt PF15704.5 EGO51857.1 - 0.062 13.2 1.1 0.086 12.7 1.1 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase subunit DUF4125 PF13526.6 EGO51857.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) COG5 PF10392.9 EGO51861.1 - 0.059 13.5 0.1 0.088 13.0 0.1 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Deltaretro_Tax PF05599.11 EGO51864.1 - 0.9 10.1 7.1 0.21 12.1 2.5 2.3 2 0 0 2 2 2 0 Deltaretrovirus Tax protein Glyco_hydro_11 PF00457.17 EGO51865.1 - 3.7e-83 277.5 20.5 4.3e-83 277.3 20.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 zf-H2C2_2 PF13465.6 EGO51866.1 - 3.1e-05 24.2 1.7 3.1e-05 24.2 1.7 4.2 4 0 0 4 4 4 2 Zinc-finger double domain Zn_clus PF00172.18 EGO51866.1 - 8.7e-05 22.6 11.9 0.00025 21.1 11.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EGO51866.1 - 0.0041 17.5 6.1 0.0041 17.5 6.1 4.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGO51866.1 - 1.1 9.3 18.1 0.28 11.2 3.7 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger p450 PF00067.22 EGO51867.1 - 7.4e-69 232.7 0.0 9e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 EGO51869.1 - 1.5e-19 70.2 0.5 2.8e-19 69.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO51869.1 - 5.9e-19 68.0 0.8 5.9e-19 68.0 0.8 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EGO51869.1 - 1.7e-05 24.4 1.0 3.2e-05 23.5 1.0 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGO51869.1 - 0.016 16.2 0.0 0.032 15.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGO51869.1 - 0.018 14.4 2.4 0.031 13.6 2.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EGO51869.1 - 0.023 14.9 0.3 0.04 14.2 0.3 1.3 1 0 0 1 1 1 0 TrkA-N domain Atg14 PF10186.9 EGO51871.1 - 1.1e-14 54.3 0.1 2e-14 53.4 0.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 EGO51871.1 - 2.1e-08 33.5 2.7 0.0059 15.5 0.1 3.5 3 1 0 3 3 3 3 Vacuolar protein sorting 38 SKG6 PF08693.10 EGO51871.1 - 0.0035 16.7 6.5 0.0088 15.4 6.5 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DAP10 PF07213.11 EGO51871.1 - 0.086 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 DAP10 membrane protein EphA2_TM PF14575.6 EGO51871.1 - 0.11 13.5 0.0 0.25 12.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 EGO51871.1 - 0.13 12.0 1.0 0.26 11.1 1.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cupin_4 PF08007.12 EGO51871.1 - 0.52 9.7 1.8 2.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Cupin superfamily protein SUIM_assoc PF16619.5 EGO51872.1 - 0.21 11.7 15.7 1 9.4 4.8 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AAA PF00004.29 EGO51875.1 - 1.3e-40 138.9 0.0 2.2e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO51875.1 - 7.2e-07 28.9 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGO51875.1 - 6.6e-05 22.9 0.1 0.00043 20.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGO51875.1 - 0.00012 22.4 0.0 0.0069 16.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EGO51875.1 - 0.00028 21.0 0.0 0.00083 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGO51875.1 - 0.00066 20.1 0.1 0.014 15.8 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EGO51875.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EGO51875.1 - 0.0081 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGO51875.1 - 0.023 14.9 0.0 0.063 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGO51875.1 - 0.036 13.6 0.0 0.097 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGO51875.1 - 0.05 13.8 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGO51875.1 - 0.054 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EGO51875.1 - 0.063 13.0 0.0 0.59 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGO51875.1 - 0.08 12.6 0.1 0.28 10.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EGO51875.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EGO51875.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cpn60_TCP1 PF00118.24 EGO51876.1 - 2.5e-150 501.4 15.1 2.8e-150 501.2 15.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3924 PF13062.6 EGO51876.1 - 0.095 12.7 0.2 0.32 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) Rav1p_C PF12234.8 EGO51877.1 - 0.33 9.3 0.2 0.82 8.0 0.1 1.5 1 1 0 1 1 1 0 RAVE protein 1 C terminal RRM_1 PF00076.22 EGO51878.1 - 1.7e-19 69.4 0.5 8.5e-19 67.2 0.1 1.9 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGO51878.1 - 1.4e-06 28.0 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO51878.1 - 0.00047 20.0 0.0 0.0015 18.3 0.0 1.7 1 1 1 2 2 2 1 Occluded RNA-recognition motif Frankia_peptide PF14407.6 EGO51878.1 - 0.0079 16.2 0.0 2.1 8.4 0.0 2.4 2 1 0 2 2 2 2 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. RRM_8 PF11835.8 EGO51878.1 - 0.039 14.2 0.0 0.048 13.9 0.0 1.1 1 0 0 1 1 1 0 RRM-like domain STIMATE PF12400.8 EGO51879.1 - 9e-41 139.3 1.4 9e-41 139.3 1.4 1.5 2 0 0 2 2 2 1 STIMATE family DUF4666 PF15697.5 EGO51879.1 - 0.18 12.5 3.3 0.19 12.4 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) ArfGap PF01412.18 EGO51881.1 - 1.8e-34 118.3 0.5 7.1e-34 116.4 0.0 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EGO51881.1 - 3.9e-22 79.1 15.4 6.1e-22 78.5 15.4 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EGO51881.1 - 2.3e-12 47.3 0.1 5.4e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 PH domain DUF4200 PF13863.6 EGO51881.1 - 0.014 15.8 1.3 0.014 15.8 1.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) PilJ PF13675.6 EGO51881.1 - 0.13 12.3 2.2 0.3 11.1 0.6 2.4 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term PH_9 PF15410.6 EGO51881.1 - 2.6 8.5 5.1 1.2 9.5 0.7 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain PMM PF03332.13 EGO51884.1 - 7.4e-102 339.8 0.1 8.6e-102 339.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EGO51884.1 - 0.00015 21.6 0.0 0.00053 19.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 EGO51884.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Trehalose-phosphatase DDOST_48kD PF03345.14 EGO51885.1 - 1.7e-162 541.1 0.0 1.9e-162 540.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Beach PF02138.18 EGO51887.1 - 3.3e-121 403.9 0.0 5.3e-121 403.2 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EGO51887.1 - 5.2e-12 45.8 0.0 1.9e-11 43.9 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 EGO51887.1 - 5.6e-10 39.6 0.1 1.2e-09 38.5 0.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4704 PF15787.5 EGO51887.1 - 0.0019 17.5 0.0 0.0099 15.1 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) WD40 PF00400.32 EGO51887.1 - 0.14 13.1 5.6 25 5.9 0.1 4.9 6 0 0 6 6 6 0 WD domain, G-beta repeat Peptidase_S8 PF00082.22 EGO51889.1 - 1.1e-36 126.6 4.6 1.6e-36 126.1 4.6 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGO51889.1 - 1.6e-22 80.0 0.5 4.4e-22 78.5 0.5 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 Apolipoprotein PF01442.18 EGO51889.1 - 0.13 12.1 0.2 0.24 11.2 0.2 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain ATP12 PF07542.11 EGO51892.1 - 1.6e-39 134.9 0.1 3.4e-39 133.9 0.1 1.6 1 0 0 1 1 1 1 ATP12 chaperone protein AMP-binding PF00501.28 EGO51894.1 - 2.3e-78 263.7 0.0 2.9e-78 263.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO51894.1 - 1.1e-17 64.8 0.2 3.3e-17 63.2 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyridoxal_deC PF00282.19 EGO51895.1 - 4.5e-60 203.3 0.0 6.4e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGO51895.1 - 0.0011 18.0 0.0 0.0025 16.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V HEXIM PF15313.6 EGO51895.1 - 0.016 15.4 2.4 0.95 9.6 0.0 2.4 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein Sin3a_C PF16879.5 EGO51895.1 - 0.079 12.7 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 C-terminal domain of Sin3a protein Glyco_transf_28 PF03033.20 EGO51896.1 - 0.0086 16.1 0.1 0.079 13.0 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 EGO51897.1 - 0.012 15.9 0.0 0.035 14.5 0.0 1.8 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EGO51897.1 - 0.074 12.8 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal MmgE_PrpD PF03972.14 EGO51898.1 - 1.6e-146 488.4 0.0 1.9e-146 488.1 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family HEPN_STY4199 PF18729.1 EGO51898.1 - 0.15 11.2 0.1 0.34 10.0 0.0 1.6 2 0 0 2 2 2 0 STY4199-like HEPN RabGAP-TBC PF00566.18 EGO51899.1 - 7.3e-46 156.5 0.0 1.1e-45 155.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 EGO51899.1 - 2e-05 24.2 0.8 0.0048 16.7 0.3 3.4 2 0 0 2 2 2 1 EF-hand domain GRAM PF02893.20 EGO51899.1 - 0.0012 18.7 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 GRAM domain EF-hand_7 PF13499.6 EGO51899.1 - 0.0068 16.8 0.4 0.86 10.1 0.1 2.9 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGO51899.1 - 0.0083 15.6 1.4 0.47 10.1 0.8 3.3 3 0 0 3 3 3 1 EF hand DUF3246 PF11596.8 EGO51899.1 - 7.3 5.9 9.2 1.2 8.6 3.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Pkinase PF00069.25 EGO51900.1 - 4.5e-66 222.9 0.0 5.8e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO51900.1 - 3.6e-30 105.1 0.0 5.3e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO51900.1 - 5.8e-06 25.8 0.0 8.5e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EGO51900.1 - 0.0044 16.1 0.0 0.0069 15.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EGO51900.1 - 0.007 16.3 1.5 0.073 13.0 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGO51900.1 - 0.03 13.1 0.0 0.15 10.8 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Spt20 PF12090.8 EGO51900.1 - 0.069 12.7 3.5 0.11 12.1 3.5 1.2 1 0 0 1 1 1 0 Spt20 family Haspin_kinase PF12330.8 EGO51900.1 - 0.084 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Exo_endo_phos PF03372.23 EGO51901.1 - 7.5e-05 22.4 0.0 0.00028 20.5 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 EGO51902.1 - 2.3e-26 92.8 0.0 2.9e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO51902.1 - 6e-14 51.9 0.0 8.8e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO51902.1 - 6.1e-09 35.1 0.0 6.1e-09 35.1 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGO51902.1 - 0.00015 21.8 0.0 0.0014 18.6 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pal1 PF08316.11 EGO51905.1 - 4.2e-46 157.1 0.3 4.2e-46 157.1 0.3 2.2 2 0 0 2 2 2 1 Pal1 cell morphology protein Nucleo_P87 PF07267.11 EGO51905.1 - 10 4.9 9.2 15 4.2 9.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NT-C2 PF10358.9 EGO51907.1 - 3.7e-21 75.4 0.1 5.9e-16 58.5 0.0 2.2 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins POP1 PF06978.11 EGO51908.1 - 2.5e-77 259.5 20.2 2.5e-77 259.5 20.2 1.8 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EGO51908.1 - 1.4e-27 95.9 0.0 1.4e-27 95.9 0.0 2.7 3 0 0 3 3 3 1 POPLD (NUC188) domain GCV_T_C PF08669.11 EGO51908.1 - 0.03 14.2 0.0 0.096 12.6 0.0 1.8 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain IBR PF01485.21 EGO51909.1 - 1.3e-11 44.5 32.9 3e-07 30.5 7.3 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EGO51909.1 - 0.00069 19.6 10.4 0.00069 19.6 10.4 2.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGO51909.1 - 0.0012 18.7 12.4 0.0012 18.7 12.4 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO51909.1 - 0.0026 18.0 10.5 0.0026 18.0 10.5 3.6 2 1 1 3 3 3 1 Ring finger domain Synaptobrevin PF00957.21 EGO51909.1 - 0.01 15.6 2.0 0.038 13.8 2.0 1.9 1 0 0 1 1 1 0 Synaptobrevin zf-RING_11 PF17123.5 EGO51909.1 - 1 9.2 7.9 4.2 7.2 7.9 2.2 1 0 0 1 1 1 0 RING-like zinc finger HSP70 PF00012.20 EGO51910.1 - 7.2e-84 282.1 3.5 7.2e-84 282.1 3.5 2.1 2 1 1 3 3 3 1 Hsp70 protein MreB_Mbl PF06723.13 EGO51910.1 - 5.1e-07 28.8 0.1 9.5e-07 27.9 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.6 EGO51910.1 - 0.00018 21.3 1.2 0.00018 21.3 1.2 1.8 1 1 1 2 2 2 1 Periplasmic binding protein Gar1 PF04410.14 EGO51910.1 - 0.087 12.6 2.6 0.22 11.3 2.6 1.7 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region Arabino_trans_N PF17689.1 EGO51910.1 - 1 9.5 4.6 0.42 10.8 0.5 2.3 2 1 0 2 2 2 0 Arabinosyltransferase concanavalin like domain Rrp40_N PF18311.1 EGO51911.1 - 8.6e-19 67.2 0.6 1.8e-18 66.2 0.6 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 EGO51911.1 - 2.4e-17 63.0 0.1 6.8e-17 61.6 0.1 1.8 1 0 0 1 1 1 1 KH domain zf-C2H2 PF00096.26 EGO51912.1 - 0.00067 20.0 25.9 0.072 13.6 0.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGO51912.1 - 0.00069 19.6 4.7 0.095 12.7 3.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EGO51912.1 - 0.00098 19.8 21.6 0.75 10.8 4.7 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger Adeno_E3_CR2 PF02439.15 EGO51912.1 - 0.067 13.0 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Astro_capsid_p PF12226.8 EGO51912.1 - 0.13 11.4 0.2 0.25 10.5 0.2 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FOXP-CC PF16159.5 EGO51912.1 - 0.49 11.1 4.6 0.28 11.8 2.2 1.9 1 1 0 1 1 1 0 FOXP coiled-coil domain Sina PF03145.16 EGO51912.1 - 6.7 6.6 14.4 29 4.5 12.3 2.1 1 1 1 2 2 2 0 Seven in absentia protein family SH3_1 PF00018.28 EGO51913.1 - 4.4e-16 58.2 0.1 6.9e-16 57.6 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGO51913.1 - 3.9e-09 36.0 0.0 6.7e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGO51913.1 - 4.5e-08 32.8 0.1 6.8e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain GRP PF07172.11 EGO51913.1 - 0.014 16.1 11.6 0.033 14.9 11.6 1.6 1 0 0 1 1 1 0 Glycine rich protein family DUF910 PF06014.11 EGO51913.1 - 0.085 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) SHOCT PF09851.9 EGO51913.1 - 0.22 11.3 0.1 0.32 10.8 0.1 1.2 1 0 0 1 1 1 0 Short C-terminal domain JAKMIP_CC3 PF16034.5 EGO51914.1 - 0.002 18.1 8.2 0.0022 18.0 2.4 2.6 1 1 1 2 2 2 1 JAKMIP CC3 domain Cnn_1N PF07989.11 EGO51914.1 - 0.004 17.3 5.8 0.092 12.9 5.8 2.5 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 Exonuc_VII_L PF02601.15 EGO51914.1 - 0.21 11.1 7.1 0.077 12.5 4.6 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF2115 PF09888.9 EGO51914.1 - 3 8.3 5.6 12 6.4 2.6 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) WSC PF01822.19 EGO51916.1 - 5.2e-39 132.3 37.0 3.4e-23 81.6 7.4 4.0 4 0 0 4 4 4 3 WSC domain PAN_4 PF14295.6 EGO51916.1 - 4.3e-10 39.3 0.3 4.3e-10 39.3 0.3 5.9 4 2 2 6 6 6 2 PAN domain PAN_1 PF00024.26 EGO51916.1 - 0.054 13.5 0.0 0.054 13.5 0.0 5.7 5 2 1 7 7 7 0 PAN domain CorA PF01544.18 EGO51918.1 - 0.00017 21.0 3.0 0.0012 18.2 0.1 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Glyco_hydro_25 PF01183.20 EGO51920.1 - 3.2e-44 151.2 1.1 3.7e-44 151.0 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Herpes_capsid PF06112.11 EGO51922.1 - 1.7 8.7 15.6 2.8 8.0 15.6 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Herpes_pp85 PF04637.12 EGO51922.1 - 9.5 4.5 8.7 12 4.2 8.7 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Ribosomal_L44 PF00935.19 EGO51923.1 - 2.7e-36 123.9 11.9 3.8e-36 123.4 11.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 4PPT_N PF17837.1 EGO51923.1 - 0.1 12.7 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain RRM_1 PF00076.22 EGO51924.1 - 4.9e-22 77.5 0.0 6.6e-12 45.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGO51924.1 - 0.0029 17.2 0.0 0.49 10.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 EGO51924.1 - 0.036 13.7 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_8 PF11835.8 EGO51924.1 - 0.092 13.0 0.0 0.47 10.7 0.0 2.1 3 0 0 3 3 3 0 RRM-like domain Limkain-b1 PF11608.8 EGO51924.1 - 0.11 12.6 0.0 13 6.0 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 C8 PF08742.11 EGO51925.1 - 0.098 13.1 0.6 0.098 13.1 0.6 2.1 1 1 1 2 2 2 0 C8 domain CFEM PF05730.11 EGO51925.1 - 0.9 9.7 4.1 2.1 8.5 4.1 1.6 1 1 0 1 1 1 0 CFEM domain Glyco_hydro_3_C PF01915.22 EGO51926.1 - 1.1e-38 133.3 0.0 2.3e-38 132.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO51926.1 - 1.4e-25 90.4 0.0 1.9e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGO51926.1 - 9.5e-06 25.6 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Esterase_phd PF10503.9 EGO51927.1 - 5.2e-27 94.8 0.5 1e-26 93.8 0.5 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 EGO51927.1 - 1.4e-12 47.3 13.6 5.1e-12 45.5 13.6 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 EGO51927.1 - 1.9e-09 37.3 1.2 3e-09 36.7 1.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EGO51927.1 - 7.9e-06 25.7 0.7 1.2e-05 25.1 0.7 1.2 1 0 0 1 1 1 1 Putative esterase Baculo_E66 PF04850.12 EGO51927.1 - 0.012 14.4 0.1 0.018 13.8 0.1 1.2 1 0 0 1 1 1 0 Baculovirus E66 occlusion-derived virus envelope protein Abhydrolase_3 PF07859.13 EGO51927.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGO51927.1 - 0.021 14.6 0.3 0.039 13.8 0.3 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.18 EGO51927.1 - 0.07 12.7 1.4 0.16 11.5 1.5 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family MFS_1 PF07690.16 EGO51928.1 - 3.9e-46 157.6 57.7 6.3e-45 153.6 56.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO51928.1 - 1.8e-20 72.9 19.7 2.5e-20 72.4 19.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGO51928.1 - 1.2e-17 63.9 3.2 1.2e-17 63.9 3.2 3.5 3 1 0 4 4 4 1 Sugar (and other) transporter Trypan_PARP PF05887.11 EGO51928.1 - 0.13 12.3 5.2 0.24 11.4 5.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) OAD_gamma PF04277.13 EGO51928.1 - 7.6 7.2 6.8 34 5.1 1.3 3.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain OATP PF03137.20 EGO51928.1 - 9.2 4.4 16.1 0.18 10.0 3.1 3.2 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family HMG-CoA_red PF00368.18 EGO51929.1 - 7.5e-142 472.7 7.4 1e-141 472.2 7.4 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 EGO51929.1 - 6.5e-43 146.3 1.6 1.1e-42 145.5 1.6 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 EGO51929.1 - 2.3e-12 47.0 8.0 2.4e-11 43.7 8.0 2.2 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EGO51929.1 - 2.3e-05 22.7 3.6 2.3e-05 22.7 3.6 1.5 2 0 0 2 2 2 1 Patched family Lig_chan PF00060.26 EGO51929.1 - 0.12 12.2 2.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 0 Ligand-gated ion channel Isochorismatase PF00857.20 EGO51930.1 - 1.7e-27 96.7 0.0 2e-25 90.0 0.0 2.1 1 1 0 1 1 1 1 Isochorismatase family zf-RING_2 PF13639.6 EGO51931.1 - 3.1e-11 43.4 2.0 5.8e-11 42.5 2.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGO51931.1 - 2.4e-10 40.0 1.4 5.6e-10 38.8 1.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGO51931.1 - 3.2e-07 30.1 1.6 6.5e-07 29.1 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO51931.1 - 2.4e-06 27.3 0.3 5.1e-06 26.2 0.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGO51931.1 - 0.00015 22.0 4.5 0.00053 20.2 4.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGO51931.1 - 0.00023 21.1 4.6 0.00051 20.0 4.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGO51931.1 - 0.0015 18.4 0.3 0.0033 17.2 0.3 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGO51931.1 - 0.0038 17.2 0.5 0.0072 16.3 0.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EGO51931.1 - 0.012 15.3 0.5 0.023 14.3 0.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type EphA2_TM PF14575.6 EGO51931.1 - 0.093 13.6 0.0 0.16 12.9 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain NICE-3 PF07406.11 EGO51931.1 - 0.29 11.1 0.9 0.46 10.4 0.9 1.4 1 1 0 1 1 1 0 NICE-3 protein Aldedh PF00171.22 EGO51932.1 - 3.6e-151 503.8 0.0 4.4e-151 503.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGO51932.1 - 1.6e-05 24.1 0.0 2.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 EGO51932.1 - 3.9e-05 23.2 0.0 0.17 11.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Endonuc-BglII PF09195.11 EGO51932.1 - 0.18 11.6 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Restriction endonuclease BglII Antifungal_pept PF11410.8 EGO51933.1 - 1.1 9.3 11.4 0.18 11.7 5.5 2.2 1 1 1 2 2 2 0 Antifungal peptide ThrE PF06738.12 EGO51934.1 - 1.1e-70 237.8 8.1 2.5e-69 233.3 3.8 2.5 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EGO51934.1 - 4.4e-06 26.9 1.2 4.4e-06 26.9 1.2 3.7 4 0 0 4 4 4 2 Threonine/Serine exporter, ThrE ADP_PFK_GK PF04587.15 EGO51935.1 - 0.14 10.7 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Amidoligase_2 PF12224.8 EGO51938.1 - 7.2e-19 68.5 0.4 9.5e-19 68.0 0.4 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme Ldh_1_N PF00056.23 EGO51939.1 - 2.2e-43 147.7 0.6 4.2e-43 146.8 0.6 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EGO51939.1 - 7e-24 84.6 0.1 1.3e-23 83.8 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 EGO51939.1 - 9.1e-06 25.3 2.3 0.0044 16.6 0.1 3.1 2 1 1 3 3 3 2 Family 4 glycosyl hydrolase DAO PF01266.24 EGO51939.1 - 9.9e-05 22.1 1.8 0.00032 20.4 1.7 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 EGO51939.1 - 0.0019 17.8 0.9 0.0031 17.1 0.3 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 EGO51939.1 - 0.0039 16.5 0.6 0.024 13.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EGO51939.1 - 0.0077 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EGO51939.1 - 0.009 16.3 0.2 0.028 14.7 0.2 1.9 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EGO51939.1 - 0.0093 16.0 1.0 0.02 14.9 0.3 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EGO51939.1 - 0.018 15.4 0.3 0.044 14.2 0.3 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 EGO51939.1 - 0.02 15.1 0.6 0.062 13.6 0.6 1.9 1 1 1 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 EGO51939.1 - 0.035 14.0 2.1 0.042 13.7 0.3 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EGO51939.1 - 0.097 12.3 0.6 0.43 10.2 0.3 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 EGO51939.1 - 0.15 12.3 0.5 0.44 10.8 0.5 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGO51939.1 - 0.19 12.3 1.2 0.94 10.1 0.2 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease PF00324.21 EGO51940.1 - 9.5e-126 420.2 38.5 1.2e-125 419.9 38.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO51940.1 - 2.3e-29 102.5 44.4 3.1e-29 102.1 44.4 1.1 1 0 0 1 1 1 1 Amino acid permease Amidohydro_3 PF07969.11 EGO51941.1 - 1.5e-67 229.1 4.0 1.9e-67 228.8 4.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EGO51941.1 - 1e-10 41.5 0.2 1.2e-06 28.0 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family zf-RING_2 PF13639.6 EGO51942.1 - 2.8e-07 30.7 5.3 2.8e-07 30.7 5.3 2.1 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.17 EGO51942.1 - 0.00036 20.1 0.1 0.00075 19.1 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger FANCL_C PF11793.8 EGO51942.1 - 0.00045 20.4 4.5 0.00045 20.4 4.5 1.8 2 0 0 2 2 2 1 FANCL C-terminal domain Prok-RING_1 PF14446.6 EGO51942.1 - 0.00072 19.4 6.3 0.0058 16.5 2.5 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD PF00628.29 EGO51942.1 - 0.0028 17.5 7.4 0.0055 16.6 7.4 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_UBOX PF13445.6 EGO51942.1 - 0.0035 17.3 2.2 0.0092 16.0 2.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EGO51942.1 - 0.16 11.8 6.0 0.34 10.7 6.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 EGO51942.1 - 0.2 11.8 7.7 0.42 10.8 7.7 1.6 1 0 0 1 1 1 0 RING-variant domain zf-UDP PF14569.6 EGO51942.1 - 0.29 11.3 2.5 0.63 10.2 2.5 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Zf_RING PF16744.5 EGO51942.1 - 0.58 10.3 6.0 2.4 8.3 6.0 2.0 1 1 1 2 2 2 0 KIAA1045 RING finger DUF4674 PF15719.5 EGO51942.1 - 1.3 9.0 0.0 1.3 9.0 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4674) DUF4293 PF14126.6 EGO51943.1 - 0.0072 16.6 0.1 0.022 15.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4293) ENTH PF01417.20 EGO51944.1 - 5.8e-25 87.8 0.0 8.2e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EGO51944.1 - 0.063 12.3 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 ANTH domain DUF3549 PF12069.8 EGO51944.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) Pro_isomerase PF00160.21 EGO51945.1 - 5.5e-43 147.0 0.1 6.7e-43 146.7 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_pol_Rpc34 PF05158.12 EGO51946.1 - 3e-139 464.1 0.0 3.5e-139 463.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_34 PF13601.6 EGO51946.1 - 0.00049 20.2 0.1 0.0012 18.9 0.1 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain RPA_C PF08784.11 EGO51946.1 - 0.0055 17.3 0.0 5.4 7.7 0.0 3.4 3 1 0 3 3 3 1 Replication protein A C terminal DUF188 PF02639.14 EGO51946.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 MarR PF01047.22 EGO51946.1 - 0.14 12.1 0.0 0.56 10.2 0.0 2.0 2 0 0 2 2 2 0 MarR family EndIII_4Fe-2S PF10576.9 EGO51946.1 - 0.37 11.2 2.6 0.69 10.3 2.6 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III MFS_1 PF07690.16 EGO51947.1 - 7.5e-33 113.9 25.9 1e-32 113.4 25.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily GPI-anchored PF10342.9 EGO51948.1 - 1.4e-15 57.8 5.3 1.6e-15 57.6 1.4 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Fungal_trans PF04082.18 EGO51949.1 - 6.7e-06 25.3 0.3 1.2e-05 24.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHC_N1 PF08385.12 EGO51949.1 - 0.77 8.3 1.9 1.8 7.1 0.5 2.2 3 0 0 3 3 3 0 Dynein heavy chain, N-terminal region 1 p450 PF00067.22 EGO51950.1 - 8.6e-64 216.0 0.0 1.1e-63 215.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C48 PF02902.19 EGO51954.1 - 5.2e-15 55.9 0.1 6.6e-14 52.3 0.1 2.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SLX9 PF15341.6 EGO51955.1 - 4e-40 137.2 7.3 7e-40 136.5 7.3 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Resolvase PF00239.21 EGO51955.1 - 0.01 16.0 0.7 0.024 14.7 0.5 1.7 1 1 0 1 1 1 0 Resolvase, N terminal domain Opi1 PF08618.10 EGO51955.1 - 0.013 14.7 3.5 0.015 14.5 3.5 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 ThiF PF00899.21 EGO51956.1 - 9.1e-53 179.1 0.0 1.3e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EGO51956.1 - 2e-09 37.9 0.0 8.9e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 EGO51956.1 - 0.01 15.9 0.1 0.031 14.3 0.0 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EGO51956.1 - 0.13 12.8 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 EGO51956.1 - 0.4 10.0 1.4 7.7 5.8 0.5 3.0 2 1 2 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Chromo PF00385.24 EGO51957.1 - 2.2e-10 40.3 2.9 4.3e-10 39.3 2.9 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Keratin PF02422.16 EGO51957.1 - 0.19 11.4 3.8 0.43 10.3 3.8 1.5 1 0 0 1 1 1 0 Keratin SspB PF04386.13 EGO51957.1 - 0.51 10.2 2.8 3.3 7.6 0.1 2.6 2 0 0 2 2 2 0 Stringent starvation protein B TetR_C_31 PF17940.1 EGO51960.1 - 0.11 12.7 0.0 0.37 11.0 0.1 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF761 PF05553.11 EGO51960.1 - 0.44 10.1 3.3 0.52 9.9 0.9 2.3 2 0 0 2 2 2 0 Cotton fibre expressed protein SKA2 PF16740.5 EGO51960.1 - 7 6.5 9.3 5.1 6.9 1.3 3.3 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 NAD_Gly3P_dh_N PF01210.23 EGO51961.1 - 2.6e-46 157.5 0.0 9.4e-46 155.6 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EGO51961.1 - 1.7e-36 125.6 0.0 2.8e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Shikimate_DH PF01488.20 EGO51961.1 - 0.13 12.3 0.0 5.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase hDGE_amylase PF14701.6 EGO51962.1 - 3.4e-180 599.9 0.0 4.3e-180 599.5 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EGO51962.1 - 8.8e-118 393.6 0.1 1.8e-117 392.6 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EGO51962.1 - 2.9e-87 292.5 0.0 7.9e-87 291.1 0.0 1.7 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EGO51962.1 - 9.2e-30 102.6 0.0 2.3e-29 101.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme TauE PF01925.19 EGO51963.1 - 0.00037 20.2 0.7 0.00057 19.6 0.7 1.3 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF4231 PF14015.6 EGO51963.1 - 0.026 15.0 0.9 0.048 14.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF4381 PF14316.6 EGO51963.1 - 0.1 12.8 0.5 0.18 12.1 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LapA_dom PF06305.11 EGO51963.1 - 0.18 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Vezatin PF12632.7 EGO51963.1 - 0.25 10.7 0.1 0.34 10.3 0.1 1.1 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes DUF3583 PF12126.8 EGO51967.1 - 0.62 9.5 3.1 0.86 9.0 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) HLH PF00010.26 EGO51968.1 - 3e-13 49.5 0.1 5.2e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribonuc_red_2_N PF08471.10 EGO51969.1 - 0.057 13.6 0.1 0.07 13.3 0.1 1.1 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase RCC_reductase PF06405.11 EGO51969.1 - 0.12 11.5 0.1 0.13 11.4 0.1 1.0 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) Abp2 PF09441.10 EGO51969.1 - 0.18 11.9 0.1 0.2 11.7 0.1 1.1 1 0 0 1 1 1 0 ARS binding protein 2 Vps23_core PF09454.10 EGO51970.1 - 0.14 12.1 0.0 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Vps23 core domain Tannase PF07519.11 EGO51971.1 - 7.2e-14 51.6 0.0 9.7e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase DUF3237 PF11578.8 EGO51972.1 - 8.9e-36 123.0 0.0 1.5e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.15 EGO51972.1 - 0.0019 18.2 5.9 0.71 9.9 1.1 2.7 2 0 0 2 2 2 2 BED zinc finger DUF1431 PF07248.12 EGO51972.1 - 0.29 11.4 9.8 0.32 11.3 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1431) DUF2024 PF09630.10 EGO51972.1 - 7.4 6.5 6.8 5.9 6.8 1.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF2024) MFS_1 PF07690.16 EGO51973.1 - 2.8e-41 141.6 29.7 2.8e-41 141.6 29.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Vpu PF00558.19 EGO51973.1 - 0.0033 17.2 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 Vpu protein DUF2178 PF09946.9 EGO51973.1 - 0.41 10.9 6.2 0.93 9.7 0.4 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2178) MatE PF01554.18 EGO51975.1 - 2.6e-53 180.0 24.2 3.6e-30 104.7 6.5 2.6 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EGO51975.1 - 0.005 16.9 21.9 0.0068 16.5 9.3 3.4 3 0 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain DUF4360 PF14273.6 EGO51976.1 - 5.6e-30 104.5 3.0 7.4e-30 104.1 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) WxL PF13731.6 EGO51976.1 - 0.018 15.1 0.3 0.023 14.7 0.3 1.1 1 0 0 1 1 1 0 WxL domain surface cell wall-binding Pico_P1A PF02226.16 EGO51976.1 - 0.39 10.8 4.4 0.25 11.4 1.9 2.0 2 1 0 2 2 2 0 Picornavirus coat protein (VP4) Form_Nir_trans PF01226.17 EGO51977.1 - 1e-62 211.6 24.5 1.2e-62 211.4 24.5 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Oleosin PF01277.17 EGO51977.1 - 0.58 9.9 4.6 1.1 9.0 4.6 1.4 1 0 0 1 1 1 0 Oleosin COesterase PF00135.28 EGO51981.1 - 1.5e-83 281.4 0.0 2.9e-83 280.5 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO51981.1 - 3.8e-05 23.6 0.1 8.3e-05 22.5 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO51981.1 - 0.0083 15.6 0.4 0.013 15.0 0.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family F_actin_cap_B PF01115.17 EGO51981.1 - 0.064 12.9 0.2 0.1 12.2 0.2 1.2 1 0 0 1 1 1 0 F-actin capping protein, beta subunit YobH PF13996.6 EGO51981.1 - 0.24 11.5 0.6 4.6 7.4 0.0 2.5 2 1 0 2 2 2 0 YobH-like protein Cellulase PF00150.18 EGO51982.1 - 2.6e-51 174.7 3.6 3.7e-51 174.2 3.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EGO51982.1 - 6.2e-11 42.1 15.3 6.2e-11 42.1 15.3 3.0 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.12 EGO51982.1 - 1.1 9.6 3.9 2.3 8.5 3.9 1.5 1 0 0 1 1 1 0 Toxin 7 Pkinase_Tyr PF07714.17 EGO51983.1 - 6.7e-06 25.6 0.1 0.15 11.3 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EGO51983.1 - 0.009 15.4 0.1 0.08 12.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain BSP_II PF05432.11 EGO51984.1 - 0.014 15.1 16.0 0.015 15.0 16.0 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RPA43_OB PF17875.1 EGO51984.1 - 0.22 12.1 3.4 0.23 12.1 3.4 1.1 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DUF1840 PF08895.11 EGO51984.1 - 0.68 10.3 5.7 0.75 10.2 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) FAM176 PF14851.6 EGO51984.1 - 1.2 8.8 9.9 1.3 8.7 9.9 1.1 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EGO51984.1 - 3.4 6.9 15.4 3.7 6.8 15.4 1.0 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EGO51984.1 - 4.3 7.8 17.1 4.8 7.6 17.1 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.14 EGO51984.1 - 4.8 6.9 10.8 4.7 7.0 10.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Radial_spoke PF04712.12 EGO51984.1 - 5.8 5.7 19.5 5.5 5.8 19.5 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein SDA1 PF05285.12 EGO51984.1 - 8.7 5.7 15.7 9 5.6 15.7 1.0 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.13 EGO51984.1 - 9.1 5.2 16.7 9.7 5.1 16.7 1.0 1 0 0 1 1 1 0 Paf1 AA_permease_2 PF13520.6 EGO51987.1 - 4.7e-59 200.3 46.0 6e-59 200.0 46.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO51987.1 - 3.6e-15 55.5 40.3 4.8e-15 55.1 40.3 1.1 1 0 0 1 1 1 1 Amino acid permease Edc3_linker PF16598.5 EGO51987.1 - 0.24 12.1 0.5 0.43 11.3 0.5 1.3 1 0 0 1 1 1 0 Linker region of enhancer of mRNA-decapping protein 3 DUF719 PF05334.13 EGO51988.1 - 1.7 8.8 18.9 4.8 7.3 11.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF719) Cytomega_UL84 PF06284.11 EGO51988.1 - 5.2 5.4 7.6 2.7 6.4 1.0 2.1 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein VPS13_C PF16909.5 EGO51988.1 - 5.9 6.6 6.4 4.8 6.9 4.5 1.8 1 1 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal 7tm_1 PF00001.21 EGO51990.1 - 0.031 13.6 0.9 0.1 11.9 0.3 2.0 2 1 1 3 3 3 0 7 transmembrane receptor (rhodopsin family) SID-1_RNA_chan PF13965.6 EGO51990.1 - 0.075 11.4 0.0 0.12 10.7 0.0 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Amnionless PF14828.6 EGO51990.1 - 0.084 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless Ctr PF04145.15 EGO51990.1 - 0.14 12.8 0.6 0.39 11.3 0.4 1.8 2 0 0 2 2 2 0 Ctr copper transporter family DUF4834 PF16118.5 EGO51990.1 - 0.56 11.2 2.4 2.1 9.4 2.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) TMEM100 PF16311.5 EGO51990.1 - 4.2 7.0 5.6 6.6 6.3 0.9 2.3 1 1 1 2 2 2 0 Transmembrane protein 100 RRM_1 PF00076.22 EGO51991.1 - 4.7e-46 154.5 0.0 1.8e-16 59.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGO51991.1 - 7.5e-07 29.1 0.1 0.0029 17.6 0.1 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGO51991.1 - 6.8e-05 22.9 0.0 0.0023 18.0 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 EGO51991.1 - 0.00068 19.7 0.0 0.068 13.3 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 EGO51991.1 - 0.0033 17.3 0.0 0.067 13.0 0.0 2.6 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EGO51991.1 - 0.043 13.4 0.0 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 7TM_GPCR_Srab PF10292.9 EGO51992.1 - 0.19 10.6 0.2 0.25 10.2 0.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor Ecm29 PF13001.7 EGO51993.1 - 2.6e-154 514.6 0.2 1.6e-153 512.0 0.0 2.3 2 0 0 2 2 2 1 Proteasome stabiliser ERAP1_C PF11838.8 EGO51993.1 - 7.3e-05 22.5 0.9 1.4 8.4 0.0 4.6 4 1 1 5 5 5 2 ERAP1-like C-terminal domain Vac14_Fab1_bd PF12755.7 EGO51993.1 - 0.0025 18.4 0.1 0.43 11.2 0.1 3.9 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGO51993.1 - 0.048 13.9 8.5 1.2 9.5 0.1 6.9 7 0 0 7 7 7 0 HEAT repeat CRIC_ras_sig PF10534.9 EGO51993.1 - 0.12 12.6 0.0 0.69 10.1 0.0 2.4 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras HEAT_EZ PF13513.6 EGO51993.1 - 4.4 7.9 15.6 50 4.5 0.0 8.2 8 0 0 8 8 8 0 HEAT-like repeat Thioredoxin_7 PF13899.6 EGO51994.1 - 1.4e-18 66.9 0.1 2.7e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 EGO51994.1 - 2.3e-13 49.7 0.5 4.6e-13 48.7 0.5 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EGO51994.1 - 2.8e-06 27.4 0.0 6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.15 EGO51994.1 - 0.011 15.6 0.1 0.02 14.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Trypan_PARP PF05887.11 EGO51994.1 - 6.6 6.7 12.7 0.15 12.1 4.9 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.25 EGO51995.1 - 2.4e-66 223.8 0.0 6.2e-66 222.5 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO51995.1 - 9.1e-48 162.8 0.0 1.9e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AltA1 PF16541.5 EGO51996.1 - 1.9e-13 51.2 0.8 4.1e-13 50.2 0.6 1.7 1 1 0 1 1 1 1 Alternaria alternata allergen 1 THEG4 PF15834.5 EGO51997.1 - 0.16 12.0 0.7 0.25 11.3 0.7 1.2 1 0 0 1 1 1 0 Testis highly expressed protein 4 Iso_dh PF00180.20 EGO51998.1 - 1.3e-81 274.5 0.0 1.7e-81 274.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Tyrosinase PF00264.20 EGO51999.1 - 1.7e-53 182.2 0.3 1.7e-53 182.2 0.3 2.0 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EGO51999.1 - 1.1e-36 126.2 0.0 2.7e-36 124.9 0.0 1.7 1 0 0 1 1 1 1 Tyosinase C-terminal domain WBS_methylT PF12589.8 EGO52000.1 - 8.3e-14 52.1 5.7 1.7e-13 51.1 5.7 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EGO52000.1 - 8e-12 45.6 0.0 1.4e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO52000.1 - 3.5e-10 40.4 0.0 9.2e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO52000.1 - 2.1e-05 25.1 0.0 6.9e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGO52000.1 - 9e-05 22.3 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGO52000.1 - 0.00016 21.5 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGO52000.1 - 0.0034 16.7 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGO52000.1 - 0.0058 16.5 0.0 0.0094 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGO52000.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Erv26 PF04148.13 EGO52001.1 - 7.2e-96 319.9 0.2 8.1e-96 319.7 0.2 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 2-Hacid_dh_C PF02826.19 EGO52004.1 - 5.1e-58 195.4 0.0 6.9e-58 194.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGO52004.1 - 1.4e-27 96.0 0.0 1.9e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGO52004.1 - 5.2e-06 26.7 0.0 8.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EGO52004.1 - 0.0047 17.0 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 EGO52004.1 - 0.059 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DpaA_N PF16924.5 EGO52004.1 - 0.16 12.0 0.0 0.87 9.7 0.0 2.0 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain RRM PF10378.9 EGO52005.1 - 0.93 9.3 7.2 0.31 10.8 3.2 2.2 2 1 1 3 3 3 0 Putative RRM domain MFS_1 PF07690.16 EGO52006.1 - 2.6e-34 118.7 27.8 2.6e-34 118.7 27.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily COX7a PF02238.15 EGO52006.1 - 1.7 9.1 4.6 12 6.4 0.1 3.8 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII FMO-like PF00743.19 EGO52008.1 - 5.9e-20 71.2 0.0 7.4e-19 67.6 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGO52008.1 - 2.4e-11 43.4 0.0 2.4e-10 40.1 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO52008.1 - 1.2e-10 41.6 2.3 1.8e-09 37.8 0.1 3.2 2 2 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGO52008.1 - 1.5e-10 41.1 0.2 3.8e-09 36.6 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EGO52008.1 - 7.3e-09 35.2 0.6 1.3e-06 27.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 EGO52008.1 - 1.5e-08 34.4 0.0 2.5e-05 23.8 0.0 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.24 EGO52008.1 - 1e-07 31.9 0.1 6.4e-07 29.3 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO52008.1 - 3.5e-06 26.5 0.1 0.011 15.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO52008.1 - 0.00096 18.5 0.5 0.0029 16.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 EGO52008.1 - 0.0016 19.0 0.3 3.8 8.2 0.3 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO52008.1 - 0.0026 16.5 0.2 0.025 13.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 EGO52008.1 - 0.019 13.8 0.1 0.4 9.5 0.0 2.4 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.19 EGO52008.1 - 0.02 14.1 0.0 0.041 13.1 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 EGO52008.1 - 0.16 10.7 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 MCRA family EZH2_N PF18601.1 EGO52008.1 - 0.16 12.3 0.1 0.44 10.9 0.1 1.6 1 0 0 1 1 1 0 EZH2 N-terminal domain GIDA PF01134.22 EGO52008.1 - 0.18 10.8 0.2 5.3 6.0 0.0 2.3 2 1 0 2 2 2 0 Glucose inhibited division protein A 7tm_2 PF00002.24 EGO52009.1 - 3.3e-09 36.4 10.0 3.3e-09 36.4 10.0 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 EGO52009.1 - 1.6e-08 34.0 7.3 2.7e-08 33.3 7.3 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.8 EGO52009.1 - 0.00068 19.5 9.0 0.0013 18.5 9.0 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 EGO52009.1 - 0.048 12.7 6.6 0.077 12.0 6.6 1.4 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region DUF3669 PF12417.8 EGO52010.1 - 1e-20 73.7 0.1 1.6e-19 69.9 0.0 2.3 2 0 0 2 2 2 1 Zinc finger protein Dynamin_N PF00350.23 EGO52011.1 - 1.7e-32 112.8 0.0 4.1e-32 111.5 0.0 1.7 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 EGO52011.1 - 9.6e-14 51.3 0.0 1.1e-11 44.5 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EGO52011.1 - 0.00012 22.1 0.0 0.00035 20.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGO52011.1 - 0.038 14.4 0.2 0.68 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EGO52011.1 - 0.16 12.5 0.0 0.71 10.4 0.0 2.1 1 0 0 1 1 1 0 ABC transporter DUF4515 PF14988.6 EGO52011.1 - 7.7 6.3 7.1 2.3 8.0 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4515) RSN1_7TM PF02714.15 EGO52012.1 - 7.2e-74 248.5 25.7 7.2e-74 248.5 25.7 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EGO52012.1 - 7.1e-39 133.8 0.0 1.1e-38 133.2 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EGO52012.1 - 1.3e-34 119.2 1.7 1.3e-34 119.2 1.7 3.0 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DEADboxA PF12343.8 EGO52012.1 - 2.5 8.7 9.1 5 7.7 9.1 1.4 1 0 0 1 1 1 0 Cold shock protein DEAD box A MutS_V PF00488.21 EGO52013.1 - 7e-51 172.9 0.6 8.7e-49 166.1 0.4 2.3 1 1 1 2 2 2 2 MutS domain V MutS_III PF05192.18 EGO52013.1 - 7.4e-14 52.4 0.4 1.5e-13 51.4 0.4 1.5 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 EGO52013.1 - 0.0014 19.0 0.1 0.0047 17.2 0.1 1.9 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.6 EGO52013.1 - 0.065 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EGO52013.1 - 0.17 12.4 0.2 1.8 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain K_trans PF02705.16 EGO52014.1 - 2.6e-179 597.2 16.4 3e-179 597.0 16.4 1.0 1 0 0 1 1 1 1 K+ potassium transporter Aminotran_4 PF01063.19 EGO52016.1 - 1.7e-20 73.8 0.0 2.2e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Glyco_transf_20 PF00982.21 EGO52017.1 - 1.1e-165 552.0 0.0 1.5e-165 551.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGO52017.1 - 1.6e-41 142.0 0.0 2.5e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase WD40 PF00400.32 EGO52018.1 - 7.9e-51 168.9 32.4 6.1e-10 39.5 0.4 9.0 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO52018.1 - 2.6e-23 82.1 5.9 6.5e-05 23.2 0.0 6.7 3 3 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGO52018.1 - 6.9e-07 29.3 0.1 0.00053 19.9 0.0 3.4 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGO52018.1 - 1.5e-06 27.4 0.0 0.65 8.9 0.0 4.8 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGO52018.1 - 8.2e-05 21.4 2.3 0.19 10.4 0.2 5.1 4 2 2 6 6 6 1 Nucleoporin Nup120/160 WD40_like PF17005.5 EGO52018.1 - 0.0027 17.1 0.0 2 7.7 0.0 3.7 4 1 0 4 4 4 1 WD40-like domain DinB PF05163.12 EGO52018.1 - 0.039 13.9 0.0 0.087 12.7 0.0 1.5 2 0 0 2 2 2 0 DinB family Nbas_N PF15492.6 EGO52018.1 - 0.057 12.7 0.1 3 7.1 0.0 3.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal NLE PF08154.12 EGO52018.1 - 0.084 13.4 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 NLE (NUC135) domain PQQ_3 PF13570.6 EGO52018.1 - 0.12 12.9 1.7 3.8 8.1 0.3 4.0 4 2 1 5 5 5 0 PQQ-like domain PD40 PF07676.12 EGO52018.1 - 0.23 11.5 3.1 28 4.8 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Na_Ca_ex PF01699.24 EGO52019.1 - 9.4e-39 132.8 36.0 3e-21 76.0 16.1 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF917 PF06032.12 EGO52020.1 - 2e-126 421.5 1.3 3.9e-126 420.6 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 EGO52020.1 - 1.3e-26 93.6 4.5 1.3e-24 87.0 0.6 3.3 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EGO52020.1 - 6.9e-26 91.0 0.1 4.1e-23 82.0 0.0 3.0 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 EGO52020.1 - 0.003 16.2 1.1 0.069 11.7 0.0 2.5 2 0 0 2 2 2 1 MutL protein BcrAD_BadFG PF01869.20 EGO52020.1 - 0.0099 15.4 5.3 0.54 9.7 0.0 3.5 4 0 0 4 4 4 2 BadF/BadG/BcrA/BcrD ATPase family Epimerase PF01370.21 EGO52021.1 - 2.9e-07 30.2 0.0 9.2e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGO52021.1 - 2.2e-06 27.7 0.0 3.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGO52021.1 - 4.8e-05 22.9 0.0 8.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGO52021.1 - 0.0022 17.0 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EGO52021.1 - 0.0059 16.2 0.2 0.012 15.2 0.3 1.5 1 1 0 1 1 1 1 NmrA-like family DcuA_DcuB PF03605.14 EGO52021.1 - 0.17 10.7 0.1 0.24 10.3 0.1 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter S-methyl_trans PF02574.16 EGO52023.1 - 4.7e-63 213.5 0.0 5.4e-63 213.3 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase NCD1 PF04904.13 EGO52023.1 - 0.18 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) Pkinase PF00069.25 EGO52024.1 - 2.2e-07 30.5 0.0 4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain JHY PF15261.6 EGO52025.1 - 0.038 14.7 4.7 0.06 14.1 4.5 1.6 1 1 0 1 1 1 0 Jhy protein Sugar_tr PF00083.24 EGO52027.1 - 2.5e-80 270.6 22.1 5.4e-80 269.5 22.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO52027.1 - 4.1e-28 98.3 33.8 1.5e-27 96.5 31.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGO52027.1 - 2.1e-05 23.3 3.8 2.1e-05 23.3 3.8 3.0 3 1 0 3 3 3 1 MFS/sugar transport protein MFS_4 PF06779.14 EGO52027.1 - 0.0081 15.5 8.6 0.027 13.8 3.3 2.4 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 EGO52027.1 - 0.058 11.8 7.0 0.017 13.6 2.9 1.9 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) ATP1G1_PLM_MAT8 PF02038.16 EGO52027.1 - 0.27 10.7 1.3 1.4 8.4 1.3 2.2 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family MFS_3 PF05977.13 EGO52027.1 - 0.5 8.7 8.7 0.015 13.7 0.6 2.3 3 0 0 3 3 3 0 Transmembrane secretion effector FtsX PF02687.21 EGO52029.1 - 0.016 15.7 3.7 0.016 15.7 3.7 3.7 2 2 0 2 2 2 0 FtsX-like permease family Kinocilin PF15033.6 EGO52029.1 - 0.034 13.8 0.1 0.074 12.7 0.1 1.5 1 0 0 1 1 1 0 Kinocilin protein MFS_1 PF07690.16 EGO52030.1 - 2.8e-30 105.4 25.9 2.8e-30 105.4 25.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TIP_N PF12457.8 EGO52031.1 - 0.019 15.3 0.1 0.021 15.2 0.1 1.1 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal ARL17 PF15840.5 EGO52032.1 - 0.012 16.0 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor-like protein 17 DUF2205 PF10224.9 EGO52033.1 - 6.8e-36 122.1 1.7 9.3e-36 121.7 1.7 1.2 1 0 0 1 1 1 1 Short coiled-coil protein SKA2 PF16740.5 EGO52033.1 - 0.024 14.4 1.2 0.035 13.9 1.2 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 AAA_32 PF13654.6 EGO52033.1 - 0.037 12.8 0.1 0.042 12.6 0.1 1.1 1 0 0 1 1 1 0 AAA domain LCD1 PF09798.9 EGO52033.1 - 0.1 11.1 2.2 0.12 10.8 2.2 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein ApoO PF09769.9 EGO52033.1 - 0.18 11.8 0.1 0.25 11.3 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein O Fungal_trans PF04082.18 EGO52035.1 - 4.2e-10 39.1 1.6 8.4e-10 38.1 1.6 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO52035.1 - 0.011 15.9 1.5 0.02 15.0 1.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 EGO52036.1 - 4.9e-94 315.7 18.2 5.7e-94 315.5 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO52036.1 - 1.3e-29 103.3 38.6 1e-28 100.3 20.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_2_C PF02836.17 EGO52038.1 - 8.5e-109 363.3 0.0 1.1e-108 362.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 EGO52038.1 - 5.4e-66 222.7 0.0 8.3e-66 222.0 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 EGO52038.1 - 1.5e-49 168.2 0.2 3.2e-49 167.1 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 EGO52038.1 - 7e-20 71.3 0.0 1.7e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 EGO52038.1 - 1.2e-12 48.4 0.2 2.5e-12 47.5 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 RNR_inhib PF08591.10 EGO52039.1 - 0.043 15.1 0.2 0.1 13.9 0.2 1.7 1 0 0 1 1 1 0 Ribonucleotide reductase inhibitor RNase_PH PF01138.21 EGO52040.1 - 1.2e-36 126.2 0.1 1.8e-36 125.6 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Thioredoxin PF00085.20 EGO52041.1 - 1.3e-30 105.4 0.0 1.3e-25 89.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EGO52041.1 - 1.6e-06 28.5 0.1 0.011 16.2 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EGO52041.1 - 0.00021 20.7 0.0 0.00079 18.9 0.0 1.9 2 1 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EGO52041.1 - 0.0044 16.9 0.0 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EGO52041.1 - 0.0048 17.2 0.0 0.29 11.5 0.0 3.2 3 1 0 3 3 3 1 Thioredoxin-like TraF PF13728.6 EGO52041.1 - 0.006 16.4 0.0 0.006 16.4 0.0 3.1 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 EGO52041.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 EGO52041.1 - 0.18 11.6 0.0 0.76 9.5 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin Vta1 PF04652.16 EGO52042.1 - 3.4e-47 160.1 3.1 5.8e-47 159.3 1.2 1.9 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 EGO52042.1 - 9.2e-18 63.7 0.1 9.2e-18 63.7 0.1 2.0 2 0 0 2 2 2 1 Vta1 C-terminal domain Sua5_yciO_yrdC PF01300.18 EGO52045.1 - 0.019 14.5 0.0 0.67 9.4 0.0 2.4 2 0 0 2 2 2 0 Telomere recombination Sugar_tr PF00083.24 EGO52046.1 - 5.6e-112 374.9 22.4 6.9e-112 374.6 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO52046.1 - 7.9e-27 94.1 28.6 1.8e-19 69.9 7.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGO52046.1 - 3.6e-05 22.5 4.0 3.6e-05 22.5 4.0 2.9 2 2 1 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 EGO52046.1 - 0.0019 16.6 9.6 0.0021 16.4 1.1 2.8 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family E1_DerP2_DerF2 PF02221.15 EGO52047.1 - 0.37 11.2 1.8 0.84 10.1 0.0 2.3 3 0 0 3 3 3 0 ML domain KfrA_N PF11740.8 EGO52048.1 - 0.063 14.0 5.4 0.93 10.2 0.9 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Polysacc_deac_1 PF01522.21 EGO52048.1 - 0.071 13.0 0.8 0.19 11.6 0.7 1.7 2 0 0 2 2 2 0 Polysaccharide deacetylase TFIIA PF03153.13 EGO52048.1 - 0.077 13.0 5.1 2.6 8.0 1.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 EGO52048.1 - 3.9 7.4 6.0 19 5.1 2.2 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SUIM_assoc PF16619.5 EGO52048.1 - 4.3 7.5 17.4 0.22 11.6 0.3 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 JAB PF01398.21 EGO52050.1 - 2.8e-32 111.2 0.0 5e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGO52050.1 - 4.8e-12 46.3 0.3 9.3e-12 45.4 0.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EGO52050.1 - 4.7e-07 29.6 0.0 8.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 EGO52050.1 - 0.14 12.2 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Hist_deacetyl PF00850.19 EGO52051.1 - 6.5e-75 252.5 0.2 1.4e-74 251.4 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain Abhydrolase_1 PF00561.20 EGO52052.1 - 7.7e-26 91.3 0.0 5.4e-25 88.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EGO52052.1 - 9.7e-23 80.2 0.0 2.3e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Herpes_gE PF02480.16 EGO52053.1 - 0.014 14.2 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Bacteriocin_IIc PF10439.9 EGO52053.1 - 0.48 10.6 6.3 1.3 9.2 6.3 1.7 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Tim17 PF02466.19 EGO52055.1 - 3.4e-16 59.6 0.6 5e-16 59.1 0.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ferric_reduct PF01794.19 EGO52056.1 - 2.2e-22 79.5 12.9 5.4e-22 78.2 12.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGO52056.1 - 1.3e-19 70.9 0.0 1.9e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGO52056.1 - 4.6e-12 46.0 0.0 1.1e-11 44.7 0.0 1.6 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 EGO52056.1 - 3.7e-05 24.3 0.0 0.00031 21.4 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Sdh_cyt PF01127.22 EGO52056.1 - 0.0042 17.1 9.7 0.013 15.5 6.7 2.6 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4018 PF13210.6 EGO52056.1 - 5.4 6.8 10.8 0.086 12.6 3.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4018) Ctr PF04145.15 EGO52057.1 - 8e-40 136.9 1.9 9.7e-40 136.6 1.9 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Peptidase_S28 PF05577.12 EGO52058.1 - 1.4e-52 178.9 0.1 2.4e-52 178.2 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 HemY_N PF07219.13 EGO52060.1 - 0.23 11.7 0.4 0.39 10.9 0.4 1.3 1 0 0 1 1 1 0 HemY protein N-terminus HMG_box_2 PF09011.10 EGO52061.1 - 1.5e-26 92.8 28.8 0.0014 19.2 0.0 9.3 9 0 0 9 9 9 8 HMG-box domain HMG_box PF00505.19 EGO52061.1 - 2.4e-21 75.9 25.4 0.00021 21.7 0.1 9.8 10 0 0 10 10 10 8 HMG (high mobility group) box Hrs_helical PF12210.8 EGO52061.1 - 0.085 13.4 1.7 12 6.5 0.0 3.7 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate MFS_1 PF07690.16 EGO52062.1 - 3.5e-13 49.2 35.4 2.3e-08 33.3 15.6 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF3021 PF11457.8 EGO52062.1 - 0.34 11.2 11.0 0.061 13.6 6.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) CPP1-like PF11833.8 EGO52062.1 - 4.8 6.8 7.7 8.3 6.0 4.9 2.4 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like VSP PF03302.13 EGO52063.1 - 0.00011 21.1 0.1 0.00011 21.1 0.1 2.1 2 0 0 2 2 2 1 Giardia variant-specific surface protein Podoplanin PF05808.11 EGO52063.1 - 0.01 16.0 0.1 0.02 15.0 0.1 1.4 1 0 0 1 1 1 1 Podoplanin Glyco_hydro_61 PF03443.14 EGO52064.1 - 9.5e-48 162.8 0.2 1.4e-47 162.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EGO52064.1 - 6.2e-12 45.3 12.7 2.7e-11 43.2 12.7 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Serglycin PF04360.12 EGO52064.1 - 0.0011 18.9 0.9 0.0023 17.9 0.9 1.5 1 0 0 1 1 1 1 Serglycin 6PGD PF00393.19 EGO52065.1 - 6.2e-76 255.6 0.0 1.4e-71 241.2 0.0 2.1 1 1 1 2 2 2 2 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGO52065.1 - 7.2e-22 78.2 0.0 1.3e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGO52065.1 - 0.17 12.1 0.1 0.36 11.1 0.1 1.5 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase AP_endonuc_2 PF01261.24 EGO52066.1 - 2e-48 164.7 0.0 3.1e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel CDH1_2_SANT_HL1 PF18375.1 EGO52066.1 - 0.1 13.3 0.6 9.5 7.0 0.4 2.6 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 Csm2_III-A PF03750.13 EGO52067.1 - 0.09 13.6 1.4 3.4 8.5 0.4 2.7 2 1 0 2 2 2 0 Csm2 Type III-A ZapB PF06005.12 EGO52068.1 - 0.0065 16.9 4.0 0.0065 16.9 4.0 11.8 3 1 3 6 6 6 2 Cell division protein ZapB Prenyltrans PF00432.21 EGO52069.1 - 0.041 13.6 1.7 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Formyl_trans_N PF00551.19 EGO52070.1 - 1.7e-37 128.9 0.0 2.2e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase DUF1917 PF08939.10 EGO52073.1 - 1.5e-57 195.5 5.1 2.2e-57 194.9 0.1 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF1917) T2SSF PF00482.23 EGO52073.1 - 0.11 12.4 0.2 0.25 11.3 0.2 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF4887 PF16228.5 EGO52073.1 - 0.84 9.8 5.4 1.3 9.1 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) AMP-binding PF00501.28 EGO52078.1 - 0.14 10.7 0.0 4.1 5.9 0.0 2.2 2 0 0 2 2 2 0 AMP-binding enzyme DUF4407 PF14362.6 EGO52080.1 - 0.002 17.5 6.0 0.0025 17.2 6.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DivIC PF04977.15 EGO52080.1 - 0.0026 17.5 21.0 0.0063 16.3 4.4 3.9 3 1 1 4 4 4 2 Septum formation initiator bZIP_1 PF00170.21 EGO52080.1 - 0.0038 17.3 19.6 0.059 13.5 3.5 4.0 4 1 1 5 5 5 2 bZIP transcription factor ZapB PF06005.12 EGO52080.1 - 0.091 13.2 24.6 0.11 12.9 5.9 3.6 2 1 1 3 3 3 0 Cell division protein ZapB DUF4751 PF15942.5 EGO52080.1 - 0.094 12.7 0.3 0.2 11.6 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4751) TSC22 PF01166.18 EGO52080.1 - 0.12 12.7 13.1 0.79 10.1 1.2 4.4 3 1 1 4 4 4 0 TSC-22/dip/bun family Exonuc_VII_L PF02601.15 EGO52080.1 - 0.18 11.3 4.2 0.22 11.1 4.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_DNA_bd PF12329.8 EGO52080.1 - 1.6 8.8 23.2 19 5.4 1.1 4.3 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF2203 PF09969.9 EGO52080.1 - 1.8 9.3 12.0 0.75 10.5 2.8 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) UPF0242 PF06785.11 EGO52080.1 - 2.1 8.4 16.2 11 6.1 16.0 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SHE3 PF17078.5 EGO52080.1 - 2.6 7.7 16.8 6.4 6.4 13.6 2.8 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Spectrin PF00435.21 EGO52080.1 - 3.3 8.2 12.5 9 6.8 5.4 2.8 2 1 1 3 3 3 0 Spectrin repeat bZIP_2 PF07716.15 EGO52080.1 - 6.1 7.0 19.8 0.71 10.0 1.2 4.3 3 1 2 5 5 5 0 Basic region leucine zipper Glyco_hydro_43 PF04616.14 EGO52081.1 - 5.8e-19 68.5 0.0 7.6e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 HD PF01966.22 EGO52082.1 - 0.017 15.3 0.0 0.046 14.0 0.0 1.7 2 1 0 2 2 2 0 HD domain SnoaL PF07366.12 EGO52086.1 - 4.5e-15 55.6 0.5 3.2e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EGO52086.1 - 0.00017 22.2 0.2 0.0015 19.1 0.0 2.7 3 0 0 3 3 3 1 SnoaL-like domain MFS_1 PF07690.16 EGO52087.1 - 2.3e-43 148.5 48.3 9.7e-42 143.1 46.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO52087.1 - 6.1e-20 71.2 11.7 8.8e-20 70.6 11.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGO52087.1 - 6.7e-15 54.9 33.6 2.5e-14 53.0 12.6 3.2 1 1 3 4 4 4 2 Sugar (and other) transporter Zip PF02535.22 EGO52089.1 - 2.6e-54 184.7 1.4 3.3e-54 184.3 1.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter UPF0261 PF06792.11 EGO52092.1 - 6.6e-166 552.2 0.0 7.4e-166 552.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) FYRC PF05965.14 EGO52092.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 F/Y rich C-terminus SURNod19 PF07712.12 EGO52092.1 - 0.18 10.5 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 Stress up-regulated Nod 19 PEP_hydrolase PF09370.10 EGO52093.1 - 1.9e-135 450.2 0.4 2.2e-135 450.1 0.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 EGO52093.1 - 8.4e-05 22.1 0.1 0.00012 21.6 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Cupin_1 PF00190.22 EGO52094.1 - 1e-44 151.8 0.0 1.8e-22 79.6 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EGO52094.1 - 1.3e-27 95.3 0.8 2.9e-13 49.3 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EGO52094.1 - 4.3e-10 39.2 0.0 0.00011 21.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EGO52094.1 - 2.7e-07 30.6 0.1 0.00082 19.3 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 EGO52094.1 - 0.0011 18.9 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.14 EGO52094.1 - 0.0012 19.1 0.3 0.23 11.7 0.1 2.3 2 0 0 2 2 2 1 ARD/ARD' family GPI PF06560.11 EGO52094.1 - 0.037 13.3 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_7 PF12973.7 EGO52094.1 - 0.054 13.4 0.3 0.47 10.4 0.1 2.5 2 1 0 2 2 2 0 ChrR Cupin-like domain cNMP_binding PF00027.29 EGO52094.1 - 0.11 12.6 0.0 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain 3-HAO PF06052.12 EGO52094.1 - 0.13 11.9 0.0 2.6 7.7 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Dicty_REP PF05086.12 EGO52095.1 - 0.14 10.1 2.1 0.14 10.1 2.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 EGO52095.1 - 0.76 7.9 8.9 1.2 7.2 8.9 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 EGO52095.1 - 2 8.4 11.7 0.23 11.4 7.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF1275 PF06912.11 EGO52096.1 - 7.4e-49 166.3 14.6 8.8e-49 166.0 14.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Phage_holin_3_6 PF07332.11 EGO52096.1 - 1.1 9.3 8.9 0.12 12.4 2.4 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4131 PF13567.6 EGO52096.1 - 2.4 7.8 6.7 13 5.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Hemerythrin PF01814.23 EGO52097.1 - 1.7e-11 44.9 0.0 2.3e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Acetyltransf_10 PF13673.7 EGO52098.1 - 7.5e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO52098.1 - 0.0018 18.7 0.0 0.0026 18.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO52098.1 - 0.0022 18.2 0.0 0.0032 17.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Phage_T4_Ndd PF06591.11 EGO52099.1 - 0.18 11.6 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) SET PF00856.28 EGO52100.1 - 3.1e-14 53.7 0.0 1.8e-13 51.2 0.0 2.2 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 EGO52100.1 - 1.2e-07 31.2 17.7 0.00059 19.8 2.6 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGO52100.1 - 7.2e-06 25.6 8.9 0.078 12.8 2.8 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGO52100.1 - 0.0061 16.8 8.7 9.4 6.6 0.5 4.0 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO52100.1 - 0.05 13.8 16.1 0.11 12.8 2.3 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Arm-DNA-bind_4 PF14657.6 EGO52100.1 - 0.13 12.0 0.5 0.27 11.0 0.5 1.6 1 0 0 1 1 1 0 Arm DNA-binding domain TPR_7 PF13176.6 EGO52100.1 - 0.35 11.0 5.2 39 4.6 0.5 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGO52100.1 - 0.71 10.7 2.6 6.1 7.8 2.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGO52100.1 - 0.87 10.1 2.9 13 6.4 0.3 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat NPR3 PF03666.13 EGO52101.1 - 0.0021 17.0 7.9 0.0026 16.6 7.9 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.8 EGO52101.1 - 0.0023 16.8 0.8 0.0035 16.2 0.8 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 AAR2 PF05282.11 EGO52101.1 - 0.019 14.4 1.2 0.028 13.8 1.2 1.3 1 0 0 1 1 1 0 AAR2 protein Dapper PF15268.6 EGO52101.1 - 0.053 12.4 3.6 0.062 12.2 3.6 1.1 1 0 0 1 1 1 0 Dapper Presenilin PF01080.17 EGO52101.1 - 0.1 11.3 12.5 0.14 10.9 12.5 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EGO52101.1 - 0.11 11.7 3.5 0.14 11.4 3.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Otopetrin PF03189.13 EGO52101.1 - 0.27 10.0 2.8 0.31 9.8 2.8 1.1 1 0 0 1 1 1 0 Otopetrin GEMIN8 PF15348.6 EGO52101.1 - 0.46 10.7 3.5 0.72 10.1 3.5 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Neur_chan_memb PF02932.16 EGO52101.1 - 0.56 10.2 3.7 0.84 9.6 3.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SLC12 PF03522.15 EGO52101.1 - 0.59 9.1 11.1 0.82 8.6 11.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Striatin PF08232.12 EGO52101.1 - 1.2 9.7 8.0 2.3 8.8 8.0 1.4 1 0 0 1 1 1 0 Striatin family DUF936 PF06075.12 EGO52101.1 - 1.6 7.5 9.8 2.4 7.0 9.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Macoilin PF09726.9 EGO52101.1 - 5.9 5.3 16.1 7.9 4.9 16.1 1.1 1 0 0 1 1 1 0 Macoilin family SUR7 PF06687.12 EGO52102.1 - 6.4e-29 101.1 0.5 7.4e-29 100.9 0.5 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 EGO52102.1 - 9.9e-08 32.1 5.9 9.9e-08 32.1 5.9 1.5 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Trp_oprn_chp PF09534.10 EGO52102.1 - 0.00019 21.3 2.8 0.00021 21.1 0.3 1.9 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Mem_trans PF03547.18 EGO52102.1 - 0.025 13.0 0.1 0.042 12.3 0.1 1.3 1 0 0 1 1 1 0 Membrane transport protein Choline_transpo PF04515.12 EGO52102.1 - 2.3 7.3 9.3 4.6 6.4 6.9 2.0 2 0 0 2 2 2 0 Plasma-membrane choline transporter DUF2569 PF10754.9 EGO52102.1 - 5.9 7.3 10.0 0.14 12.6 2.8 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) Tetraspanin PF00335.20 EGO52102.1 - 6.8 6.3 11.5 0.25 11.0 4.4 2.0 2 1 1 3 3 3 0 Tetraspanin family Fructosamin_kin PF03881.14 EGO52103.1 - 1.5e-29 103.1 0.0 2e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase MFS_1 PF07690.16 EGO52104.1 - 7.1e-47 160.0 24.0 4.5e-43 147.5 13.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO52104.1 - 1.9e-09 36.9 8.8 1.9e-09 36.9 8.8 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter Ferric_reduct PF01794.19 EGO52105.1 - 1.1e-17 64.3 12.2 1.1e-17 64.3 12.2 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGO52105.1 - 1.8e-05 24.7 3.0 5e-05 23.3 0.1 2.6 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 EGO52105.1 - 6e-05 23.2 0.0 0.026 14.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DUF1917 PF08939.10 EGO52105.1 - 0.15 11.9 0.1 6.7 6.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) Collagen_mid PF15984.5 EGO52106.1 - 0.00056 19.7 14.5 0.0011 18.7 14.5 1.5 1 1 0 1 1 1 1 Bacterial collagen, middle region Senescence PF06911.12 EGO52106.1 - 0.00098 19.5 7.7 0.0015 18.8 7.7 1.4 1 1 0 1 1 1 1 Senescence-associated protein CsbD PF05532.12 EGO52106.1 - 0.012 15.5 0.3 0.012 15.5 0.3 2.2 2 1 0 2 2 2 0 CsbD-like Coiled PF05710.12 EGO52106.1 - 0.26 12.1 8.7 0.085 13.7 5.6 1.7 1 1 1 2 2 2 0 Coiled coil VPS13_C PF16909.5 EGO52106.1 - 1.3 8.8 5.2 3.8 7.2 1.8 2.1 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal WD40 PF00400.32 EGO52108.1 - 1.6e-17 63.6 3.4 2.9e-09 37.4 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO52108.1 - 0.00077 19.7 0.0 0.12 12.6 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO52108.1 - 0.00083 18.4 0.0 0.041 12.8 0.0 2.1 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PUL PF08324.11 EGO52109.1 - 6.5e-62 209.3 0.1 9e-62 208.8 0.1 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EGO52109.1 - 3.6e-45 152.9 0.3 6.2e-45 152.1 0.3 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EGO52109.1 - 2.2e-29 101.0 12.9 3e-07 31.0 1.2 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat SRR1 PF07985.12 EGO52112.1 - 2.4e-07 30.7 0.0 7e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 SRR1 DMRT-like PF15791.5 EGO52112.1 - 0.081 13.4 3.0 0.13 12.7 3.0 1.3 1 0 0 1 1 1 0 Doublesex-and mab-3-related transcription factor C1 and C2 PAN_4 PF14295.6 EGO52113.1 - 1.6e-10 40.7 3.5 3e-10 39.8 3.5 1.5 1 0 0 1 1 1 1 PAN domain Epimerase PF01370.21 EGO52114.1 - 1.2e-07 31.5 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EGO52114.1 - 4.8e-05 23.8 0.0 9.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EGO52114.1 - 5.1e-05 23.2 0.0 8.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGO52114.1 - 0.029 13.4 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Peptidase_C101 PF16218.5 EGO52114.1 - 0.029 13.6 0.1 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Peptidase family C101 KR PF08659.10 EGO52114.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.12 EGO52114.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein DXP_reductoisom PF02670.16 EGO52114.1 - 0.19 12.4 0.0 0.34 11.6 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2-Hacid_dh_C PF02826.19 EGO52118.1 - 4.1e-47 159.8 0.3 5.6e-46 156.1 0.3 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGO52118.1 - 1e-07 31.7 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AOC_like PF18678.1 EGO52118.1 - 0.059 13.0 0.3 0.15 11.7 0.3 1.6 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain THDPS_N_2 PF14805.6 EGO52118.1 - 0.083 13.1 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal adh_short PF00106.25 EGO52119.1 - 1.4e-35 122.5 0.0 1.8e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO52119.1 - 4e-28 98.6 0.0 4.7e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO52119.1 - 7.8e-12 45.5 0.2 2.6e-11 43.8 0.2 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO52119.1 - 0.045 13.2 0.0 0.14 11.6 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO52119.1 - 0.14 11.1 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ras PF00071.22 EGO52120.1 - 2.3e-40 137.9 0.0 6.2e-40 136.4 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGO52120.1 - 4.9e-30 104.2 0.0 7e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO52120.1 - 1.1e-10 41.3 0.0 3.9e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGO52120.1 - 0.00061 19.8 0.0 0.00092 19.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGO52120.1 - 0.0032 16.8 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGO52120.1 - 0.025 14.0 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 EGO52120.1 - 0.033 14.3 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGO52120.1 - 0.045 14.1 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EGO52120.1 - 0.046 13.6 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 EGO52120.1 - 0.049 13.9 0.1 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EGO52120.1 - 0.069 12.9 0.0 0.52 10.0 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EGO52120.1 - 0.074 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EGO52120.1 - 0.085 13.4 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 EGO52120.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 1 0 1 1 1 0 RsgA GTPase Mannosidase_ig PF17786.1 EGO52121.1 - 6.8e-17 61.9 0.2 4.3e-16 59.3 0.1 2.4 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EGO52121.1 - 1.4e-11 45.1 0.1 4.4e-11 43.4 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 EGO52121.1 - 8.8e-05 22.2 0.3 0.00046 19.9 0.0 2.4 2 0 0 2 2 2 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 EGO52121.1 - 0.003 17.5 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain CIDE-N PF02017.15 EGO52121.1 - 0.0074 16.3 0.1 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 CIDE-N domain Glyco_hydro_2_C PF02836.17 EGO52121.1 - 0.035 13.2 0.4 0.13 11.3 0.4 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain ADH_N PF08240.12 EGO52122.1 - 2.6e-30 104.5 1.1 5.4e-30 103.5 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO52122.1 - 1.5e-24 86.4 0.2 3.4e-24 85.3 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGO52122.1 - 4.9e-09 36.0 0.7 8.7e-09 35.2 0.7 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGO52122.1 - 1.2e-06 29.6 0.1 3.7e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGO52122.1 - 1.5e-05 24.4 1.5 2.2e-05 23.9 1.5 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Met_10 PF02475.16 EGO52122.1 - 0.0014 18.4 0.3 0.004 16.9 0.1 1.7 2 0 0 2 2 2 1 Met-10+ like-protein Pyr_redox_2 PF07992.14 EGO52122.1 - 0.0014 17.9 0.3 0.003 16.8 0.3 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EGO52122.1 - 0.0047 16.5 0.1 0.042 13.4 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 EGO52122.1 - 0.0064 15.3 0.5 0.023 13.4 0.4 1.8 2 0 0 2 2 2 1 HI0933-like protein 2-Hacid_dh_C PF02826.19 EGO52122.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PALP PF00291.25 EGO52122.1 - 0.028 13.8 2.3 0.029 13.8 1.0 1.6 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Methyltransf_25 PF13649.6 EGO52122.1 - 0.054 14.2 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.21 EGO52122.1 - 0.1 12.6 0.4 0.24 11.4 0.4 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.27 EGO52122.1 - 0.13 12.8 0.5 0.33 11.5 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FtsJ PF01728.19 EGO52122.1 - 0.14 12.3 0.1 0.35 10.9 0.1 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Mur_ligase_M PF08245.12 EGO52123.1 - 0.017 15.1 0.1 0.12 12.3 0.0 2.5 2 1 0 2 2 2 0 Mur ligase middle domain Mitofilin PF09731.9 EGO52124.1 - 3e-170 568.2 13.5 8.8e-170 566.6 13.5 1.7 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Ras PF00071.22 EGO52124.1 - 5.3e-58 195.2 0.6 1.1e-57 194.2 0.6 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO52124.1 - 5.9e-35 120.1 0.2 1.8e-34 118.5 0.1 1.9 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO52124.1 - 3.1e-14 52.8 0.1 7e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGO52124.1 - 1.8e-06 27.5 0.1 3.2e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGO52124.1 - 1.4e-05 24.7 1.6 1.6e-05 24.6 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGO52124.1 - 3.4e-05 23.9 0.7 8.2e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO52124.1 - 0.026 14.5 6.9 0.49 10.3 0.5 3.0 2 1 0 3 3 3 0 RsgA GTPase DUF4363 PF14276.6 EGO52124.1 - 0.17 12.0 3.4 0.59 10.3 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) DUF1848 PF08902.11 EGO52124.1 - 0.19 11.4 1.8 2.4 7.8 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) AAA_16 PF13191.6 EGO52124.1 - 0.48 10.8 6.7 0.82 10.0 0.0 3.4 3 1 0 3 3 3 0 AAA ATPase domain Fib_alpha PF08702.10 EGO52124.1 - 6.1 7.0 6.9 9.9 6.3 4.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FAM76 PF16046.5 EGO52124.1 - 6.4 6.0 12.6 13 5.0 12.6 1.5 1 1 0 1 1 1 0 FAM76 protein Syja_N PF02383.18 EGO52125.1 - 3.8e-91 305.7 0.0 4.9e-91 305.4 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Tropomyosin_1 PF12718.7 EGO52126.1 - 0.00015 21.9 1.3 0.00051 20.2 1.3 1.9 1 0 0 1 1 1 1 Tropomyosin like Spc7 PF08317.11 EGO52126.1 - 0.00021 20.3 0.9 0.00037 19.5 0.9 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein SlyX PF04102.12 EGO52126.1 - 0.0032 18.0 5.3 0.47 11.1 0.2 3.1 2 1 1 3 3 2 2 SlyX PG_binding_1 PF01471.18 EGO52126.1 - 0.014 15.5 0.0 6.5 7.0 0.0 3.0 2 0 0 2 2 2 0 Putative peptidoglycan binding domain NPV_P10 PF05531.12 EGO52126.1 - 0.034 14.6 0.4 1.6 9.3 0.2 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 EGO52126.1 - 0.072 13.1 1.0 0.16 12.0 1.0 1.6 1 0 0 1 1 1 0 Laminin Domain II BLOC1_2 PF10046.9 EGO52126.1 - 0.08 13.2 1.1 0.23 11.8 0.7 2.0 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SbcD_C PF12320.8 EGO52126.1 - 0.099 13.0 0.5 0.35 11.2 0.5 2.0 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain Exonuc_VII_L PF02601.15 EGO52126.1 - 0.13 11.8 0.6 0.32 10.5 0.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 EGO52126.1 - 0.18 12.3 2.3 0.72 10.4 2.3 2.1 1 0 0 1 1 1 0 Apg6 coiled-coil region ATG16 PF08614.11 EGO52126.1 - 1 9.6 7.5 0.33 11.2 2.4 2.8 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Rx_N PF18052.1 EGO52126.1 - 1.1 9.6 3.1 6.1 7.2 2.9 2.3 1 1 0 1 1 1 0 Rx N-terminal domain FlaC_arch PF05377.11 EGO52126.1 - 8.7 6.8 5.5 5.2 7.5 0.2 2.9 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) CLTH PF10607.9 EGO52127.1 - 2.2e-29 102.2 0.0 5.2e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EGO52127.1 - 9.2e-07 28.8 0.4 1.6e-06 28.0 0.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 EGO52127.1 - 0.00037 19.9 0.0 0.00072 19.0 0.0 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 EGO52127.1 - 0.002 18.4 0.5 0.0034 17.7 0.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO52127.1 - 0.0022 17.8 1.3 0.0038 17.0 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO52127.1 - 0.0023 17.9 0.2 0.0037 17.2 0.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO52127.1 - 0.0099 15.7 0.8 0.018 14.9 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cwf_Cwc_15 PF04889.12 EGO52127.1 - 0.023 14.4 11.3 0.038 13.7 11.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-C3HC4_3 PF13920.6 EGO52127.1 - 0.024 14.5 0.3 0.04 13.8 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO52127.1 - 0.036 13.9 0.2 0.064 13.1 0.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 CENP-B_dimeris PF09026.10 EGO52127.1 - 0.073 13.5 16.5 0.16 12.4 16.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EGO52127.1 - 0.11 11.8 13.0 0.19 11.0 13.0 1.3 1 0 0 1 1 1 0 NOA36 protein POX PF07526.11 EGO52127.1 - 0.18 12.4 1.1 0.33 11.5 0.3 1.8 2 0 0 2 2 1 0 Associated with HOX BUD22 PF09073.10 EGO52127.1 - 0.27 10.5 4.6 0.35 10.1 4.6 1.2 1 0 0 1 1 1 0 BUD22 zf-C3HC4_4 PF15227.6 EGO52127.1 - 0.28 11.4 0.8 0.54 10.5 0.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RXT2_N PF08595.11 EGO52127.1 - 0.45 10.5 3.7 0.97 9.4 3.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Pes-10 PF07149.11 EGO52127.1 - 0.57 9.2 6.7 0.84 8.6 6.7 1.2 1 0 0 1 1 1 0 Pes-10 zf-Nse PF11789.8 EGO52127.1 - 0.67 9.8 4.1 0.55 10.1 2.2 1.8 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit Flagellin_N PF00669.20 EGO52127.1 - 0.68 10.0 3.5 0.49 10.5 0.7 2.2 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region Pox_Ag35 PF03286.14 EGO52127.1 - 1.2 8.9 6.1 0.69 9.7 3.7 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 EGO52127.1 - 1.4 7.0 14.2 2.1 6.3 14.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 EGO52127.1 - 2.1 8.5 12.4 3.5 7.8 12.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 EGO52127.1 - 4.7 7.1 12.5 7.3 6.5 12.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.9 EGO52127.1 - 5 6.1 17.6 7.5 5.6 17.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) YL1 PF05764.13 EGO52127.1 - 8.4 6.4 9.2 14 5.7 9.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein PsbI PF02532.14 EGO52128.1 - 0.072 13.0 0.9 0.072 13.0 0.9 2.8 3 0 0 3 3 3 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) DUF3377 PF11857.8 EGO52128.1 - 2.3 8.2 4.2 1.8 8.6 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) PPP4R2 PF09184.11 EGO52129.1 - 9.1e-07 28.7 0.0 9.1e-07 28.7 0.0 3.0 2 1 1 3 3 3 1 PPP4R2 GATA PF00320.27 EGO52130.1 - 5.6e-16 57.8 5.4 1.1e-15 56.9 5.4 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 EGO52130.1 - 6.9e-15 55.1 0.0 1.3e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 EGO52130.1 - 2.6e-05 24.3 0.0 5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EGO52130.1 - 3.9e-05 23.6 0.1 0.00013 21.9 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EGO52130.1 - 0.00045 20.4 0.1 0.0021 18.3 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EGO52130.1 - 0.00082 19.6 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold Zn-ribbon_8 PF09723.10 EGO52130.1 - 0.011 15.8 0.2 0.022 14.8 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 EGO52130.1 - 0.2 11.2 0.7 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.6 EGO52130.1 - 5.9 6.9 5.4 1.1 9.2 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) FAD-oxidase_C PF02913.19 EGO52131.1 - 2.2e-60 204.4 0.0 3.2e-60 203.8 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGO52131.1 - 1.4e-36 125.3 0.2 5.2e-36 123.4 0.0 2.1 2 1 1 3 3 3 1 FAD binding domain Amidase PF01425.21 EGO52132.1 - 2.9e-62 211.1 0.1 4.5e-62 210.5 0.1 1.2 1 0 0 1 1 1 1 Amidase Glyco_tranf_2_3 PF13641.6 EGO52136.1 - 4.4e-22 79.1 0.0 5.9e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGO52136.1 - 5.8e-06 25.9 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_64 PF09258.10 EGO52136.1 - 0.00013 21.3 0.4 0.00022 20.6 0.4 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glycos_transf_2 PF00535.26 EGO52136.1 - 0.00025 20.9 0.1 0.0011 18.9 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase family 2 GWT1 PF06423.12 EGO52138.1 - 3.4e-42 144.1 4.9 2.5e-41 141.3 3.3 2.4 2 0 0 2 2 2 1 GWT1 DUF4818 PF16089.5 EGO52138.1 - 0.00057 20.3 0.0 0.0024 18.3 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4818) Pkinase PF00069.25 EGO52139.1 - 3e-64 216.9 0.0 6.7e-64 215.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO52139.1 - 3.4e-36 124.9 0.0 1.4e-30 106.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGO52139.1 - 7.2e-07 28.8 2.5 6.2e-05 22.4 0.0 2.6 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGO52139.1 - 0.0062 15.9 1.1 0.014 14.7 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGO52139.1 - 0.0084 15.1 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGO52139.1 - 0.019 14.9 14.4 0.19 11.6 12.5 3.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EGO52139.1 - 0.039 13.6 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family tRNA-synt_2 PF00152.20 EGO52140.1 - 3.9e-71 239.7 0.0 5.1e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGO52140.1 - 6.3e-08 32.5 0.2 5e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain NARP1 PF12569.8 EGO52140.1 - 9.4 5.0 7.3 14 4.4 7.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Na_Ca_ex PF01699.24 EGO52141.1 - 5.3e-37 127.1 31.9 8e-23 81.1 17.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein AP3D1 PF06375.11 EGO52141.1 - 0.81 9.9 8.5 0.055 13.7 2.5 2.0 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Clr5 PF14420.6 EGO52142.1 - 6.1e-19 68.0 1.3 6.1e-19 68.0 1.3 2.3 2 0 0 2 2 2 1 Clr5 domain SDA1 PF05285.12 EGO52142.1 - 0.0021 17.6 12.0 0.0021 17.6 12.0 3.0 2 1 1 3 3 3 1 SDA1 CDC45 PF02724.14 EGO52142.1 - 1.8 6.8 31.5 0.15 10.3 17.7 2.4 2 0 0 2 2 2 0 CDC45-like protein SPRY PF00622.28 EGO52143.1 - 0.066 13.3 0.1 0.19 11.8 0.1 1.8 1 1 0 1 1 1 0 SPRY domain Spt20 PF12090.8 EGO52143.1 - 9.3 5.8 15.0 16 5.0 15.0 1.3 1 0 0 1 1 1 0 Spt20 family DEAD PF00270.29 EGO52144.1 - 7.4e-25 87.7 0.0 2.7e-23 82.6 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO52144.1 - 2.9e-23 82.3 0.1 3.3e-22 78.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO52144.1 - 7.3e-06 26.1 2.6 0.0003 20.8 0.0 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit RNase_H2_suC PF08615.11 EGO52144.1 - 0.54 10.4 5.4 4 7.6 0.2 3.0 3 0 0 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) tRNA-synt_1 PF00133.22 EGO52145.1 - 2.8e-155 518.0 0.0 3.8e-155 517.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EGO52145.1 - 1.5e-20 73.3 0.0 7.6e-13 48.0 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGO52145.1 - 1.4e-19 70.6 0.4 4.8e-19 68.8 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA DUF35_N PF12172.8 EGO52145.1 - 0.025 14.5 2.8 0.068 13.1 2.8 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) tRNA-synt_1e PF01406.19 EGO52145.1 - 0.026 13.9 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain CotE PF10628.9 EGO52146.1 - 0.41 10.3 3.9 0.89 9.2 0.2 2.3 1 1 1 2 2 2 0 Outer spore coat protein E (CotE) YndJ PF14158.6 EGO52149.1 - 0.2 10.9 0.6 0.28 10.5 0.6 1.2 1 0 0 1 1 1 0 YndJ-like protein Tom37 PF10568.9 EGO52152.1 - 2.3e-30 105.4 3.7 4.8e-30 104.4 3.7 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 EGO52152.1 - 0.00035 21.3 0.0 0.0021 18.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EGO52152.1 - 0.0055 16.5 0.1 0.014 15.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PIG-U PF06728.13 EGO52153.1 - 3.9e-125 417.9 27.5 4.5e-125 417.7 27.5 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.13 EGO52153.1 - 0.00014 21.9 1.0 0.00014 21.9 1.0 2.0 1 1 1 2 2 2 1 Mannosyltransferase (PIG-M) 8TM_micro PF17028.5 EGO52153.1 - 0.17 11.6 10.9 0.68 9.6 10.9 2.1 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain Pescadillo_N PF06732.11 EGO52154.1 - 3.1e-122 407.4 0.0 3.1e-122 407.4 0.0 2.0 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 EGO52154.1 - 0.00013 22.3 0.0 0.00055 20.3 0.0 2.1 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGO52154.1 - 0.00087 19.6 0.0 0.0081 16.5 0.0 2.6 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Astro_capsid_p PF12226.8 EGO52154.1 - 1.6 7.8 27.7 0.06 12.5 12.7 2.3 2 0 0 2 2 2 0 Turkey astrovirus capsid protein RRN9 PF10680.9 EGO52155.1 - 5.5e-21 74.6 3.8 5.5e-21 74.6 3.8 2.5 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor Kinesin PF00225.23 EGO52156.1 - 3.9e-111 371.2 0.2 3.9e-111 371.2 0.2 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGO52156.1 - 5.2e-26 91.4 1.8 1.7e-25 89.7 0.0 2.7 2 1 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 EGO52156.1 - 2.7e-06 27.8 1.0 2.7e-06 27.8 1.0 5.3 5 1 1 6 6 6 2 Kinesin-associated microtubule-binding DUF2935 PF11155.8 EGO52156.1 - 0.34 11.2 0.0 0.34 11.2 0.0 4.9 3 3 1 4 4 4 0 Domain of unknown function (DUF2935) UPF0183 PF03676.14 EGO52157.1 - 2.1e-47 162.3 0.0 3.1e-27 95.9 0.0 3.6 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) UPF0240 PF06784.11 EGO52158.1 - 0.029 14.5 0.3 0.069 13.2 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) DUF883 PF05957.13 EGO52158.1 - 1.4 9.6 5.1 41 4.9 1.4 3.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) zf-Tim10_DDP PF02953.15 EGO52159.1 - 9.1e-18 63.7 1.9 1e-17 63.5 1.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.9 EGO52159.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase tRNA-synt_2 PF00152.20 EGO52160.1 - 2.1e-67 227.5 0.0 2.9e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGO52160.1 - 1.4e-12 47.4 0.0 2.7e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGO52160.1 - 2.2e-05 24.1 0.0 0.03 13.8 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) ArfGap PF01412.18 EGO52161.1 - 0.39 10.8 1.7 0.59 10.2 0.4 2.1 2 1 0 2 2 2 0 Putative GTPase activating protein for Arf PH_6 PF15406.6 EGO52163.1 - 7.6e-48 161.5 5.7 7.6e-48 161.5 5.7 3.0 2 1 2 4 4 4 1 Pleckstrin homology domain PH PF00169.29 EGO52163.1 - 0.00058 20.3 0.0 0.0017 18.9 0.0 1.9 1 1 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 EGO52163.1 - 0.21 11.6 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 PH domain Aldedh PF00171.22 EGO52164.1 - 9.5e-169 561.8 0.0 1.1e-168 561.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_79C PF16862.5 EGO52165.1 - 4.7e-24 85.3 0.1 9.3e-24 84.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain HATPase_c PF02518.26 EGO52168.1 - 1.4e-22 80.3 0.0 2.5e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGO52168.1 - 8e-19 67.9 0.0 2.8e-14 53.2 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain PAS PF00989.25 EGO52168.1 - 1.9e-07 31.1 0.3 2.1e-06 27.7 0.0 2.8 3 0 0 3 3 3 1 PAS fold HisKA PF00512.25 EGO52168.1 - 9.2e-07 28.8 0.1 2.4e-06 27.5 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EGO52168.1 - 2.3e-05 24.6 0.0 0.00029 21.0 0.0 2.9 3 0 0 3 3 3 1 PAS domain PAS_4 PF08448.10 EGO52168.1 - 3e-05 24.2 0.0 0.004 17.4 0.0 3.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 EGO52168.1 - 8.4e-05 22.5 0.1 0.0026 17.7 0.0 2.9 3 0 0 3 3 3 1 PAS domain PAS_3 PF08447.12 EGO52168.1 - 0.012 15.9 1.1 0.071 13.4 0.1 2.5 2 0 0 2 2 2 0 PAS fold GAF_3 PF13492.6 EGO52168.1 - 0.012 16.0 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 GAF domain GAF_2 PF13185.6 EGO52168.1 - 0.14 12.5 0.0 1.5 9.1 0.0 2.7 2 0 0 2 2 2 0 GAF domain zf-B_box PF00643.24 EGO52170.1 - 0.79 9.9 6.4 4.2 7.6 0.2 2.4 2 0 0 2 2 2 0 B-box zinc finger Rad1 PF02144.16 EGO52172.1 - 2.4e-67 226.9 0.0 2.9e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Bromodomain PF00439.25 EGO52173.1 - 1.6e-26 92.2 1.5 3e-26 91.3 1.5 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EGO52173.1 - 6.4e-08 32.8 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO52173.1 - 6e-07 29.4 0.3 1.5e-06 28.1 0.2 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO52173.1 - 0.00029 21.2 0.4 0.00062 20.1 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO52173.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Fn_bind PF02986.14 EGO52173.1 - 0.18 11.6 0.5 0.36 10.6 0.5 1.5 1 0 0 1 1 1 0 Fibronectin binding repeat Trehalase PF01204.18 EGO52175.1 - 4.1e-118 395.4 0.5 2.8e-117 392.7 0.5 1.9 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 EGO52175.1 - 1.9e-05 23.8 0.5 0.00011 21.2 0.1 2.0 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Beta_elim_lyase PF01212.21 EGO52176.1 - 8e-70 235.4 0.0 9.9e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EGO52176.1 - 0.00017 20.2 0.0 0.00028 19.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGO52176.1 - 0.0084 15.4 0.0 0.046 13.0 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.18 EGO52178.1 - 1.4e-12 47.2 0.4 3e-12 46.2 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Histone_H2A_C PF16211.5 EGO52178.1 - 0.024 14.4 0.0 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 C-terminus of histone H2A G6PD_bact PF10786.9 EGO52178.1 - 0.097 12.2 1.3 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) MIase PF02426.16 EGO52178.1 - 0.13 12.4 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Muconolactone delta-isomerase DUF5398 PF17376.2 EGO52181.1 - 0.04 14.5 0.0 0.064 13.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5398) Dus PF01207.17 EGO52184.1 - 3.5e-43 147.9 0.1 1e-42 146.3 0.1 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Pyrophosphatase PF00719.19 EGO52185.1 - 1.1e-57 194.3 0.2 1.4e-57 194.0 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.9 EGO52186.1 - 5.1e-23 81.0 0.4 7.4e-23 80.5 0.4 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 KorB_C PF06613.11 EGO52186.1 - 0.091 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain Sec20 PF03908.13 EGO52187.1 - 1.9e-16 59.7 0.4 1.9e-16 59.7 0.4 2.0 3 0 0 3 3 3 1 Sec20 CompInhib_SCIN PF11546.8 EGO52187.1 - 0.16 12.1 0.1 0.68 10.0 0.0 2.0 2 0 0 2 2 2 0 Staphylococcal complement inhibitor SCIN Syntaxin-6_N PF09177.11 EGO52187.1 - 1.2 9.7 6.7 1.1 9.9 0.7 3.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal UPF0242 PF06785.11 EGO52187.1 - 7.2 6.7 7.4 2.6 8.1 1.0 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Abhydrolase_6 PF12697.7 EGO52188.1 - 2.4e-21 77.4 2.6 2.4e-21 77.4 2.6 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO52188.1 - 6.3e-11 42.4 0.0 1.3e-10 41.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO52188.1 - 5.6e-06 25.8 0.0 1.2e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EGO52188.1 - 0.011 15.8 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain NAD_binding_8 PF13450.6 EGO52189.1 - 1.5e-09 37.9 0.0 5.3e-09 36.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 EGO52189.1 - 1.7e-07 30.0 0.1 2.3e-06 26.3 0.0 2.5 2 2 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGO52189.1 - 6.4e-06 25.6 0.0 0.017 14.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO52189.1 - 7.7e-05 22.0 0.0 0.069 12.3 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGO52189.1 - 0.001 19.1 0.1 0.16 11.9 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 EGO52189.1 - 0.04 13.5 0.0 0.68 9.5 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase GPI-anchored PF10342.9 EGO52192.1 - 1.6e-13 51.2 0.4 1.6e-13 51.2 0.4 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Hamartin PF04388.12 EGO52192.1 - 5.9 5.4 11.4 7.6 5.1 11.4 1.1 1 0 0 1 1 1 0 Hamartin protein SpoIIE PF07228.12 EGO52193.1 - 2.2e-11 44.0 0.7 7.8e-10 39.0 0.7 2.3 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EGO52193.1 - 8.1e-09 35.5 0.1 0.00084 19.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EGO52193.1 - 4.9e-05 23.1 0.2 9.6e-05 22.1 0.2 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C Fer2_3 PF13085.6 EGO52194.1 - 4.6e-33 113.5 0.0 7.3e-33 112.8 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EGO52194.1 - 1.5e-08 35.1 5.9 1.5e-08 35.1 5.9 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGO52194.1 - 1e-07 32.3 7.4 1e-07 32.3 7.4 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGO52194.1 - 2.8e-07 30.6 3.0 2.8e-07 30.6 3.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EGO52194.1 - 0.0033 17.4 0.3 0.0033 17.4 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 EGO52194.1 - 0.022 15.0 0.3 0.6 10.3 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 EGO52194.1 - 0.032 14.8 6.5 0.032 14.8 6.5 2.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.8 EGO52194.1 - 0.13 12.8 2.2 0.16 12.5 0.4 2.0 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_9 PF13187.6 EGO52194.1 - 0.46 10.7 11.0 2.9 8.1 9.3 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain Med12 PF09497.10 EGO52196.1 - 2.5e-27 94.9 3.3 3e-27 94.7 0.6 2.6 3 0 0 3 3 3 1 Transcription mediator complex subunit Med12 TFIIA PF03153.13 EGO52196.1 - 0.044 13.8 42.7 0.15 12.0 14.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 EGO52196.1 - 0.73 10.2 11.2 4.1 7.8 3.3 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF2722 PF10846.8 EGO52196.1 - 7 5.5 39.9 4.3 6.2 15.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Suf PF05843.14 EGO52196.1 - 8.5 6.3 27.7 0.93 9.4 8.8 2.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) THF_DHG_CYH PF00763.23 EGO52197.1 - 7.5e-25 87.5 0.0 1.1e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EGO52197.1 - 6.8e-13 48.2 0.0 1e-07 31.4 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MMS19_N PF14500.6 EGO52199.1 - 1.6e-56 191.8 1.3 1.4e-55 188.7 0.1 2.9 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 EGO52199.1 - 3.6e-18 65.9 0.0 1.8e-16 60.3 0.0 2.8 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal EMC3_TMCO1 PF01956.16 EGO52200.1 - 6.7e-55 185.4 2.2 8.5e-55 185.1 2.2 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like RNA_pol_Rbc25 PF08292.12 EGO52201.1 - 2e-10 41.0 0.1 4.2e-10 39.9 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase III subunit Rpc25 S1 PF00575.23 EGO52201.1 - 0.00089 19.5 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain S1_2 PF13509.6 EGO52201.1 - 0.0016 18.4 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 S1 domain NUFIP1 PF10453.9 EGO52202.1 - 2.5e-08 33.6 0.6 2.5e-08 33.6 0.6 2.1 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Exonuc_VII_L PF02601.15 EGO52202.1 - 0.41 10.2 4.1 0.55 9.8 4.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-CCCH PF00642.24 EGO52202.1 - 0.76 9.8 5.7 1.5 8.8 5.7 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PIEZO PF15917.5 EGO52202.1 - 2.6 7.4 8.7 5.5 6.4 8.7 1.6 1 0 0 1 1 1 0 Piezo SIL1 PF16782.5 EGO52203.1 - 1.1e-07 31.4 0.1 1e-06 28.2 0.1 2.2 1 1 0 1 1 1 1 Nucleotide exchange factor SIL1 DUF3446 PF11928.8 EGO52203.1 - 0.024 15.0 3.1 0.024 15.0 3.1 3.3 2 1 0 2 2 2 0 Early growth response N-terminal domain Rrn6 PF10214.9 EGO52203.1 - 0.14 10.7 7.4 0.011 14.3 2.9 1.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor DUF624 PF04854.14 EGO52204.1 - 0.026 14.6 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF624 DUF4913 PF16259.5 EGO52204.1 - 0.074 13.1 1.2 0.11 12.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4913) SET PF00856.28 EGO52205.1 - 4.7e-14 53.1 0.0 9.1e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 SET domain Ribosomal_S19 PF00203.21 EGO52206.1 - 3.1e-33 113.5 0.3 4.4e-33 113.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Glyco_hydro_53 PF07745.13 EGO52207.1 - 3.3e-107 358.4 0.6 3.7e-107 358.2 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 ADH_zinc_N PF00107.26 EGO52208.1 - 7e-08 32.5 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO52208.1 - 0.0014 18.5 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain BtpA PF03437.15 EGO52208.1 - 0.016 14.6 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 BtpA family IRK_C PF17655.1 EGO52208.1 - 0.04 13.5 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Inward rectifier potassium channel C-terminal domain ADH_zinc_N_2 PF13602.6 EGO52208.1 - 0.057 14.5 0.0 0.11 13.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Glutaredoxin PF00462.24 EGO52209.1 - 1.1e-13 51.2 0.0 4.6e-13 49.2 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin tRNA-synt_1f PF01921.18 EGO52209.1 - 0.012 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) TSKS PF15358.6 EGO52209.1 - 0.041 12.2 0.3 0.056 11.8 0.3 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate F-box PF00646.33 EGO52210.1 - 0.0028 17.5 0.0 0.0083 16.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain Ribosomal_L21p PF00829.21 EGO52212.1 - 2.3e-16 59.9 0.0 3.1e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.25 EGO52213.1 - 1.6e-45 155.5 0.0 1.8e-32 112.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO52213.1 - 2.7e-19 69.4 0.1 5.8e-18 65.1 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO52213.1 - 0.00092 18.6 0.0 0.18 11.1 0.0 2.9 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 EGO52213.1 - 0.016 15.1 0.4 2.2 8.2 0.0 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 EGO52213.1 - 0.1 12.2 0.3 0.28 10.7 0.0 1.9 3 0 0 3 3 3 0 RIO1 family Kdo PF06293.14 EGO52213.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PsaA_PsaB PF00223.19 EGO52213.1 - 0.31 9.2 0.0 0.46 8.6 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein CAP_N PF01213.19 EGO52213.1 - 2.4 7.6 4.8 1.1 8.6 1.2 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Ribosomal_60s PF00428.19 EGO52214.1 - 1.6e-26 92.7 13.3 1.9e-26 92.5 13.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein UBA_6 PF18039.1 EGO52214.1 - 0.074 13.0 0.2 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 UBA-like domain DUF3824 PF12868.7 EGO52214.1 - 1.3 9.6 3.6 1.8 9.2 3.6 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) SPT2 PF08243.11 EGO52215.1 - 9.8e-07 29.3 31.5 9.8e-07 29.3 31.5 2.7 2 1 0 2 2 2 1 SPT2 chromatin protein Ribosomal_S8e PF01201.22 EGO52216.1 - 1.3e-44 151.7 2.2 1.9e-44 151.2 2.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e RIBIOP_C PF04950.12 EGO52216.1 - 0.34 10.3 4.9 0.72 9.2 4.9 1.6 1 1 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Phage_holin_5_2 PF16079.5 EGO52217.1 - 0.011 16.0 0.6 0.013 15.8 0.6 1.1 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V PAP2_3 PF14378.6 EGO52218.1 - 1.4e-35 122.8 11.8 5.8e-28 97.9 1.0 2.9 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.21 EGO52218.1 - 0.00039 20.2 1.8 0.00039 20.2 1.8 2.3 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 EGO52218.1 - 0.34 11.5 3.4 0.41 11.2 0.7 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal MgtE PF01769.16 EGO52218.1 - 0.41 11.0 3.1 0.53 10.7 0.6 2.2 2 0 0 2 2 2 0 Divalent cation transporter VIT PF08487.10 EGO52219.1 - 2.2e-35 121.2 0.0 5.6e-35 119.9 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EGO52219.1 - 5.6e-26 91.3 0.0 1e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 EGO52219.1 - 4.3e-15 55.4 0.1 1.1e-14 54.0 0.1 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 EGO52219.1 - 2.1e-10 41.1 0.0 3.8e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGO52219.1 - 2e-09 38.1 0.0 8.9e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain Glyco_hydro_2_C PF02836.17 EGO52220.1 - 1.3e-11 44.1 0.1 3.5e-11 42.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 EGO52220.1 - 2.6e-09 37.7 0.1 2.8e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EGO52220.1 - 3.9e-09 36.6 1.3 5.9e-09 36.1 0.0 2.0 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain SnoaL_2 PF12680.7 EGO52221.1 - 3.2e-06 27.7 0.0 3.9e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF2358 PF10184.9 EGO52221.1 - 0.00067 19.9 0.0 0.00088 19.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) Ank_4 PF13637.6 EGO52222.1 - 6.3e-09 36.2 0.0 1.9e-05 25.1 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO52222.1 - 1.6e-07 31.8 0.0 2.8e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGO52222.1 - 6.4e-07 29.5 0.1 1.6e-05 25.1 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGO52222.1 - 0.0015 18.9 0.0 0.025 15.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EGO52222.1 - 0.0024 18.2 0.0 0.17 12.5 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat p450 PF00067.22 EGO52223.1 - 3.5e-40 138.1 0.0 8.9e-40 136.8 0.0 1.6 1 1 1 2 2 2 1 Cytochrome P450 Sugar_tr PF00083.24 EGO52224.1 - 2.2e-118 396.0 17.8 2.5e-118 395.8 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO52224.1 - 1.5e-20 73.4 42.8 7.3e-15 54.7 11.3 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily BNR_4 PF15892.5 EGO52226.1 - 1.3e-83 280.5 0.6 1.8e-83 280.1 0.6 1.1 1 0 0 1 1 1 1 BNR repeat-containing family member Beta-lactamase PF00144.24 EGO52229.1 - 2e-24 86.4 0.7 4.5e-24 85.3 0.7 1.5 1 1 0 1 1 1 1 Beta-lactamase Asp PF00026.23 EGO52230.1 - 1.5e-73 248.0 3.7 1.8e-73 247.7 3.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO52230.1 - 3.7e-13 50.1 0.9 1.9e-07 31.5 0.1 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO52230.1 - 5.5e-06 26.9 1.2 0.0012 19.4 0.5 3.1 2 1 0 2 2 2 1 Aspartyl protease OPT PF03169.15 EGO52231.1 - 9.4e-84 282.2 47.1 1.1e-83 282.0 47.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PetL PF05115.14 EGO52231.1 - 0.056 13.4 0.2 0.056 13.4 0.2 4.8 7 0 0 7 7 7 0 Cytochrome B6-F complex subunit VI (PetL) Glyco_tranf_2_3 PF13641.6 EGO52232.1 - 4.3e-22 79.1 0.0 5.6e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGO52232.1 - 3.5e-05 23.7 0.0 5.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGO52232.1 - 0.0018 17.7 0.0 0.0068 15.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 MFS_1 PF07690.16 EGO52233.1 - 1.2e-38 133.0 41.8 2.3e-36 125.5 27.3 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO52233.1 - 1.1e-06 27.8 34.3 2.5e-06 26.6 12.4 3.4 3 0 0 3 3 3 2 Sugar (and other) transporter R3H-assoc PF13902.6 EGO52233.1 - 0.075 13.4 2.0 0.2 12.1 2.0 1.6 1 0 0 1 1 1 0 R3H-associated N-terminal domain OATP PF03137.20 EGO52233.1 - 0.33 9.2 10.7 0.14 10.4 1.4 3.1 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family GRA6 PF05084.13 EGO52234.1 - 0.11 12.4 0.0 0.56 10.1 0.0 1.9 2 0 0 2 2 2 0 Granule antigen protein (GRA6) DUF3844 PF12955.7 EGO52235.1 - 1.1e-36 125.1 2.9 2e-36 124.3 2.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF PF00008.27 EGO52235.1 - 0.79 10.1 5.5 1.8 9.0 5.5 1.7 1 1 0 1 1 1 0 EGF-like domain ISG65-75 PF11727.8 EGO52236.1 - 1.2 8.3 9.5 0.06 12.6 1.4 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein Pox_A_type_inc PF04508.12 EGO52236.1 - 6 6.9 8.7 2.4 8.1 3.3 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat LSM PF01423.22 EGO52237.1 - 1.7e-21 75.7 0.5 1.9e-21 75.5 0.5 1.0 1 0 0 1 1 1 1 LSM domain WW PF00397.26 EGO52238.1 - 1.3e-09 38.0 6.6 2.4e-09 37.1 6.6 1.5 1 0 0 1 1 1 1 WW domain KinB_sensor PF16767.5 EGO52238.1 - 0.051 14.0 3.1 0.084 13.3 3.1 1.2 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF2853 PF11015.8 EGO52238.1 - 0.084 13.5 0.4 0.15 12.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) DUF4404 PF14357.6 EGO52238.1 - 5.7 7.6 8.5 0.66 10.7 4.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Peptidase_C14 PF00656.22 EGO52239.1 - 7.5e-62 209.5 0.0 9.3e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EGO52239.1 - 0.069 13.1 0.1 0.47 10.4 0.0 2.3 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain RGS PF00615.19 EGO52240.1 - 0.00046 20.5 0.0 0.0036 17.6 0.0 2.1 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF2070 PF09843.9 EGO52240.1 - 0.28 9.4 1.5 0.51 8.6 1.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Acyl-CoA_dh_1 PF00441.24 EGO52242.1 - 4.1e-31 108.2 2.1 8.2e-31 107.2 2.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGO52242.1 - 5.2e-20 71.4 0.0 9.8e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGO52242.1 - 2.3e-16 60.5 1.0 5.5e-16 59.2 1.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGO52242.1 - 1.6e-14 54.3 3.8 7.6e-14 52.1 1.6 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain MaoC_dehydrat_N PF13452.6 EGO52243.1 - 0.00018 21.6 0.1 0.012 15.7 0.0 2.6 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase TPT PF03151.16 EGO52244.1 - 2.1e-37 129.1 12.6 2.4e-37 128.9 12.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EGO52244.1 - 1.8e-07 30.7 17.0 5.5e-07 29.1 17.0 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGO52244.1 - 6.7e-05 23.1 31.3 0.0001 22.5 11.3 2.9 2 1 0 2 2 2 2 EamA-like transporter family Glyco_hydro_17 PF00332.18 EGO52247.1 - 1.4e-10 41.2 1.3 7.6e-09 35.6 0.3 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Amidoligase_2 PF12224.8 EGO52249.1 - 8.8e-08 32.1 0.1 0.00019 21.2 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme Abhydrolase_6 PF12697.7 EGO52251.1 - 1e-12 49.1 0.4 1.8e-12 48.3 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO52251.1 - 1.1e-05 24.9 0.0 0.00018 20.9 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO52251.1 - 0.0013 18.5 1.2 0.0067 16.1 0.2 2.5 2 2 1 3 3 3 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 EGO52251.1 - 0.051 13.1 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Glyco_hydro_67M PF07488.12 EGO52252.1 - 1.1e-149 497.9 0.0 1.6e-149 497.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 EGO52252.1 - 1.7e-89 299.2 0.2 2.7e-89 298.5 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 EGO52252.1 - 3.7e-25 88.6 0.0 6.5e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 EGO52252.1 - 0.00023 21.9 0.0 0.00062 20.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF4838 PF16126.5 EGO52252.1 - 0.008 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4838) Protoglobin PF11563.8 EGO52253.1 - 4.2e-59 199.0 0.0 5.3e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 Protoglobin Toxin_12 PF07740.12 EGO52254.1 - 0.0071 17.0 5.4 0.01 16.5 5.4 1.3 1 0 0 1 1 1 1 Ion channel inhibitory toxin Atracotoxin PF05353.11 EGO52254.1 - 0.011 15.7 5.1 0.015 15.3 5.1 1.3 1 0 0 1 1 1 0 Delta Atracotoxin Pkinase PF00069.25 EGO52255.1 - 0.00084 18.8 0.0 0.0013 18.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGO52255.1 - 0.2 11.6 0.2 0.36 10.7 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_71 PF03659.14 EGO52256.1 - 7.3e-131 436.4 3.8 1.1e-130 435.8 3.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 SNF2_N PF00176.23 EGO52259.1 - 1.5e-35 122.5 0.0 1.9e-33 115.6 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO52259.1 - 2.7e-06 27.7 0.1 6.5e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2458 PF10454.9 EGO52260.1 - 2 8.1 5.7 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) HSCB_C PF07743.13 EGO52261.1 - 2.7e-20 72.6 1.7 2.7e-20 72.6 1.7 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EGO52261.1 - 0.001 19.2 0.1 0.0036 17.4 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain ANAPC1 PF12859.7 EGO52261.1 - 9.9 6.7 7.9 4.2 8.0 5.2 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 PCI PF01399.27 EGO52263.1 - 9.7e-14 51.8 0.0 8e-13 48.8 0.0 2.3 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 EGO52263.1 - 0.0018 18.0 0.6 0.004 16.9 0.6 1.6 1 1 1 2 2 2 1 26S proteasome subunit RPN7 TPR_19 PF14559.6 EGO52263.1 - 0.052 14.1 1.3 1.4 9.5 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Lipase_GDSL_2 PF13472.6 EGO52264.1 - 7.9e-25 88.3 0.0 1e-24 87.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGO52264.1 - 3.8e-09 36.8 0.0 6.8e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FMN_dh PF01070.18 EGO52265.1 - 3.5e-103 345.3 0.0 4.5e-103 344.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EGO52265.1 - 2e-16 59.9 0.0 9e-16 57.8 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EGO52265.1 - 1e-05 24.9 0.2 1.6e-05 24.2 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EGO52265.1 - 8e-05 21.8 0.1 0.00039 19.5 0.0 2.1 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain ATP11 PF06644.11 EGO52265.1 - 0.06 13.1 0.3 0.099 12.4 0.3 1.2 1 0 0 1 1 1 0 ATP11 protein CRF1 PF10380.9 EGO52265.1 - 0.09 13.1 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Transcription factor CRF1 His_biosynth PF00977.21 EGO52265.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF3712 PF12505.8 EGO52266.1 - 2.4e-31 108.6 2.3 5.4e-31 107.4 2.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) PIG-P PF08510.12 EGO52266.1 - 0.021 14.8 0.1 0.033 14.1 0.1 1.3 1 0 0 1 1 1 0 PIG-P SP_C-Propep PF08999.10 EGO52266.1 - 0.053 13.3 0.3 0.086 12.6 0.3 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide LEA_2 PF03168.13 EGO52266.1 - 0.064 13.8 0.3 4.3 7.9 0.1 3.2 3 1 0 3 3 3 0 Late embryogenesis abundant protein Phage_holin_3_6 PF07332.11 EGO52266.1 - 0.25 11.4 0.7 0.41 10.7 0.7 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF929 PF06053.11 EGO52266.1 - 1.1 8.5 3.8 1.7 7.9 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) HCNGP PF07818.13 EGO52267.1 - 2.7e-27 95.2 0.1 1e-14 54.9 0.0 2.1 2 0 0 2 2 2 2 HCNGP-like protein SIS PF01380.22 EGO52268.1 - 1.5e-61 206.0 0.2 6.1e-32 110.2 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EGO52268.1 - 8.2e-18 64.9 0.0 1.7e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EGO52268.1 - 1.8e-10 40.8 0.0 5.2e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EGO52268.1 - 0.0021 17.0 0.0 0.0035 16.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Dynactin_p22 PF07426.11 EGO52268.1 - 2.1 8.2 4.6 0.64 9.9 0.1 2.4 3 0 0 3 3 3 0 Dynactin subunit p22 AAA PF00004.29 EGO52269.1 - 6.8e-43 146.2 0.0 1.2e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGO52269.1 - 7.8e-13 48.2 0.1 3.2e-11 43.0 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGO52269.1 - 2e-10 40.3 0.1 3.7e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGO52269.1 - 9.2e-08 32.6 0.0 6.7e-05 23.3 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EGO52269.1 - 1.7e-06 28.0 0.1 3.8e-05 23.7 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGO52269.1 - 2.7e-06 27.6 0.0 9.2e-06 25.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGO52269.1 - 7e-06 25.9 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGO52269.1 - 0.00022 21.5 0.1 0.006 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 EGO52269.1 - 0.00042 19.6 0.0 0.00086 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EGO52269.1 - 0.00057 20.4 0.1 0.0026 18.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGO52269.1 - 0.0012 18.4 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EGO52269.1 - 0.0022 17.2 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Prot_ATP_OB_N PF17758.1 EGO52269.1 - 0.0037 16.9 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 EGO52269.1 - 0.0042 17.3 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGO52269.1 - 0.0042 16.5 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EGO52269.1 - 0.0044 17.0 0.0 0.0096 15.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EGO52269.1 - 0.0056 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EGO52269.1 - 0.006 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 EGO52269.1 - 0.0075 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGO52269.1 - 0.0085 15.8 0.0 0.027 14.2 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 EGO52269.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EGO52269.1 - 0.018 14.8 0.6 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 EGO52269.1 - 0.022 14.5 0.0 3.8 7.2 0.0 2.7 3 0 0 3 3 2 0 Thymidylate kinase AAA_24 PF13479.6 EGO52269.1 - 0.023 14.4 0.0 0.057 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGO52269.1 - 0.039 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGO52269.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 EGO52269.1 - 0.056 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 EGO52269.1 - 0.092 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGO52269.1 - 0.097 12.0 1.9 0.14 11.4 0.0 2.3 4 0 0 4 4 4 0 KaiC Zeta_toxin PF06414.12 EGO52269.1 - 0.097 11.9 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 EGO52269.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EGO52269.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.6 EGO52269.1 - 0.66 10.4 5.5 7.9 6.9 1.7 2.6 2 1 0 2 2 2 0 AAA domain OmpH PF03938.14 EGO52269.1 - 3.2 8.1 7.1 2.1 8.7 2.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.6 EGO52269.1 - 3.7 8.0 8.3 0.41 11.0 3.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Lactamase_B_2 PF12706.7 EGO52270.1 - 6.2e-13 48.7 0.0 8.5e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGO52270.1 - 2.5e-09 37.3 0.0 3.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain VWA PF00092.28 EGO52271.1 - 0.004 17.4 0.0 0.0079 16.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DNA_topoisoIV PF00521.20 EGO52271.1 - 0.16 10.8 0.0 0.3 9.9 0.0 1.4 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF3106 PF11304.8 EGO52275.1 - 0.0028 18.1 1.5 0.8 10.2 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3106) GHMP_kinases_N PF00288.26 EGO52275.1 - 0.02 15.1 0.6 15 5.9 0.1 3.3 3 0 0 3 3 3 0 GHMP kinases N terminal domain Zn_clus PF00172.18 EGO52276.1 - 2.3e-09 37.2 13.2 3.9e-09 36.5 13.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 EGO52277.1 - 1.3e-22 80.3 22.5 1.3e-14 54.0 9.2 2.5 1 1 0 2 2 2 2 Sugar (and other) transporter Pkinase PF00069.25 EGO52278.1 - 9.7e-62 208.7 0.0 1.3e-38 132.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO52278.1 - 5.6e-27 94.6 0.0 2.5e-20 72.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EGO52278.1 - 2.9e-13 49.9 0.0 7.4e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 EGO52278.1 - 2.3e-07 30.4 0.0 0.00012 21.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PAS_9 PF13426.7 EGO52278.1 - 2.9e-05 24.3 0.0 7.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain APH PF01636.23 EGO52278.1 - 7.2e-05 22.8 0.0 0.0034 17.4 0.1 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family PAS PF00989.25 EGO52278.1 - 0.00022 21.2 0.0 0.00053 20.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold Haspin_kinase PF12330.8 EGO52278.1 - 0.011 14.7 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EGO52278.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EGO52278.1 - 0.13 11.3 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PDDEXK_10 PF07788.11 EGO52278.1 - 1 9.3 3.3 2.6 8.0 0.2 2.4 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily bZIP_1 PF00170.21 EGO52279.1 - 1.3e-05 25.2 9.4 2.2e-05 24.4 9.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGO52279.1 - 0.026 14.6 9.9 0.03 14.4 3.1 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Rrn6 PF10214.9 EGO52279.1 - 0.079 11.4 3.3 0.13 10.8 3.3 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor eIF-3_zeta PF05091.12 EGO52280.1 - 4.9e-205 682.4 0.0 6.1e-205 682.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 EGO52280.1 - 0.014 15.1 0.1 0.029 14.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF569) DRMBL PF07522.14 EGO52281.1 - 1.8e-12 47.4 0.0 3.7e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EGO52281.1 - 1e-05 25.2 0.0 2.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain LSM PF01423.22 EGO52282.1 - 3.2e-17 62.0 0.6 4.4e-17 61.5 0.6 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGO52282.1 - 0.0019 18.3 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 EGO52282.1 - 0.0075 15.9 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 Hfq protein AEP1 PF17049.5 EGO52282.1 - 0.044 12.9 0.1 0.044 12.9 0.1 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 Ada3 PF10198.9 EGO52283.1 - 1.2e-53 180.8 0.1 5.3e-53 178.7 0.0 2.1 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 DUF1682 PF07946.14 EGO52283.1 - 0.16 11.2 3.2 0.31 10.2 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) LRIF1 PF15741.5 EGO52283.1 - 0.22 10.0 6.8 0.36 9.3 6.8 1.3 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Cwf_Cwc_15 PF04889.12 EGO52283.1 - 0.44 10.3 19.0 1.1 9.0 19.0 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SPX PF03105.19 EGO52283.1 - 5.6 6.8 19.6 3 7.7 9.8 2.5 2 0 0 2 2 2 0 SPX domain Mito_carr PF00153.27 EGO52284.1 - 2.4e-64 213.3 3.9 1.7e-20 72.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGO52284.1 - 0.55 9.4 1.9 3.3 6.8 0.0 2.8 4 0 0 4 4 4 0 Gammaproteobacterial serine protease HTH_26 PF13443.6 EGO52285.1 - 0.19 12.2 0.0 0.39 11.2 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Sod_Fe_C PF02777.18 EGO52286.1 - 1.3e-14 54.2 0.0 7.4e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGO52286.1 - 0.038 14.4 0.3 0.07 13.6 0.3 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain zf-RING_2 PF13639.6 EGO52287.1 - 3.5e-12 46.4 5.9 6.8e-12 45.5 5.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO52287.1 - 2.4e-09 36.9 4.8 4.5e-09 36.0 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGO52287.1 - 3.6e-08 33.0 3.5 3.6e-08 33.0 3.5 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EGO52287.1 - 1.4e-07 31.4 1.6 1.4e-07 31.4 1.6 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGO52287.1 - 2.2e-07 31.0 2.5 5.5e-07 29.8 2.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGO52287.1 - 4.5e-07 29.6 6.3 8.5e-07 28.8 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO52287.1 - 1.7e-06 27.8 4.5 3.1e-06 27.0 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGO52287.1 - 6.8e-05 22.8 1.2 0.00013 21.9 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGO52287.1 - 0.0023 17.5 3.2 0.0045 16.6 3.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EGO52287.1 - 0.0024 17.7 7.3 0.0045 16.8 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO52287.1 - 0.0047 16.8 8.2 0.0088 15.9 8.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGO52287.1 - 0.022 14.9 9.2 0.043 14.0 9.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 EGO52287.1 - 0.16 12.1 1.4 0.39 10.8 1.4 1.7 1 0 0 1 1 1 0 Zinc-finger zf-Nse PF11789.8 EGO52287.1 - 0.3 10.9 5.4 0.65 9.9 5.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 EGO52287.1 - 0.41 11.0 3.3 1 9.7 3.3 1.7 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 EGO52287.1 - 0.48 10.6 5.8 2.3 8.5 5.8 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain YdjO PF14169.6 EGO52287.1 - 0.79 9.5 3.6 8.9 6.1 0.9 2.8 2 1 1 3 3 3 0 Cold-inducible protein YdjO zf-RING_4 PF14570.6 EGO52287.1 - 0.91 9.4 6.7 1.7 8.5 6.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4083 PF13314.6 EGO52287.1 - 1.8 8.5 3.4 4.3 7.4 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) PHD PF00628.29 EGO52287.1 - 2.3 8.2 5.8 4.5 7.2 5.8 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 EGO52287.1 - 4.7 7.4 6.3 8.1 6.7 6.3 1.4 1 0 0 1 1 1 0 RING-variant domain CAP_N PF01213.19 EGO52288.1 - 0.3 10.5 2.1 0.33 10.4 2.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Podoplanin PF05808.11 EGO52289.1 - 0.061 13.4 5.4 0.71 10.0 5.4 2.4 1 1 0 1 1 1 0 Podoplanin Adeno_E3_CR2 PF02439.15 EGO52289.1 - 0.15 11.9 0.3 0.29 10.9 0.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SAM_2 PF07647.17 EGO52291.1 - 1.4e-09 37.9 0.0 2.9e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGO52291.1 - 3.1e-05 24.3 0.0 7.5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 EGO52291.1 - 3.2e-05 24.4 0.0 0.00024 21.6 0.0 2.5 2 1 0 2 2 2 1 PH domain SAM_Ste50p PF09235.10 EGO52291.1 - 0.018 15.3 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 Ste50p, sterile alpha motif PH_11 PF15413.6 EGO52291.1 - 0.05 14.0 0.2 0.24 11.8 0.2 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain SAM_4 PF18017.1 EGO52291.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_9 PF15410.6 EGO52291.1 - 0.15 12.4 0.1 0.32 11.4 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Fungal_trans_2 PF11951.8 EGO52293.1 - 2.9e-78 263.4 0.2 3.6e-78 263.0 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO52293.1 - 4.5e-06 26.7 9.3 7.6e-06 26.0 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop14 PF04147.12 EGO52294.1 - 4.9e-288 958.1 37.0 6.3e-288 957.8 37.0 1.1 1 0 0 1 1 1 1 Nop14-like family AAA_12 PF13087.6 EGO52296.1 - 6.1e-32 110.9 0.0 7.2e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EGO52296.1 - 0.0088 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 EGO52296.1 - 0.15 11.5 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain CMD PF02627.20 EGO52296.1 - 0.2 11.8 0.0 0.64 10.1 0.0 1.8 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family SMP PF04927.12 EGO52297.1 - 0.021 15.3 0.8 0.021 15.3 0.8 2.4 2 0 0 2 2 2 0 Seed maturation protein Pkinase PF00069.25 EGO52298.1 - 2.3e-32 112.4 0.0 4.8e-19 68.7 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO52298.1 - 9.3e-13 48.1 0.0 0.00059 19.2 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 EGO52298.1 - 0.013 14.8 0.0 2.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 EGO52298.1 - 0.016 15.2 0.0 0.084 12.8 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family CAP_GLY PF01302.25 EGO52299.1 - 5.7e-16 58.3 0.1 1.2e-15 57.3 0.1 1.6 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 EGO52299.1 - 4.1e-07 29.7 8.8 0.00046 20.0 1.3 2.4 2 0 0 2 2 2 2 CLIP1 zinc knuckle zf_PR_Knuckle PF18445.1 EGO52299.1 - 0.045 13.6 1.1 4.2 7.3 0.1 2.5 2 0 0 2 2 2 0 PR zinc knuckle motif FAM76 PF16046.5 EGO52299.1 - 1 8.7 27.7 0.079 12.3 2.1 4.1 2 1 1 4 4 4 0 FAM76 protein Glutaredoxin2_C PF04399.13 EGO52299.1 - 1.2 9.0 5.5 13 5.7 0.3 2.6 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Shugoshin_N PF07558.11 EGO52299.1 - 1.3 9.0 5.5 0.46 10.4 1.9 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region NPV_P10 PF05531.12 EGO52299.1 - 2.4 8.7 9.2 3.1 8.3 0.4 3.0 4 0 0 4 4 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 EGO52299.1 - 2.9 8.2 20.1 0.14 12.5 5.9 3.8 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4055 PF13264.6 EGO52299.1 - 3 8.0 5.4 0.85 9.8 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4055) DUF812 PF05667.11 EGO52299.1 - 4.4 6.1 40.9 0.048 12.6 21.4 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF812) Csm1_N PF18504.1 EGO52299.1 - 4.8 7.6 0.0 4.8 7.6 0.0 5.9 6 1 1 7 7 7 0 Csm1 N-terminal domain DUF202 PF02656.15 EGO52300.1 - 2.6e-21 75.8 0.9 2.6e-21 75.8 0.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2975 PF11188.8 EGO52300.1 - 0.032 14.1 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) K_channel_TID PF07941.11 EGO52300.1 - 0.39 11.2 0.1 0.39 11.2 0.1 2.5 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Aldo_ket_red PF00248.21 EGO52301.1 - 7.7e-60 202.6 0.0 8.7e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SHR3_chaperone PF08229.11 EGO52302.1 - 5.3e-76 253.8 0.1 6.4e-76 253.5 0.1 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF2157 PF09925.9 EGO52302.1 - 0.031 14.1 0.1 13 5.6 0.0 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) PMP22_Claudin PF00822.20 EGO52302.1 - 0.085 12.7 1.3 25 4.7 0.1 3.1 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin family Glyco_hydro_38N PF01074.22 EGO52303.1 - 8.9e-88 294.4 0.4 1.5e-87 293.6 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EGO52303.1 - 1.1e-62 212.0 2.2 2.2e-62 210.9 1.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EGO52303.1 - 5.7e-30 103.3 0.0 1.8e-29 101.7 0.0 1.9 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EGO52303.1 - 4.6e-12 45.9 0.0 1.4e-10 41.1 0.0 2.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Pol_alpha_B_N PF08418.10 EGO52304.1 - 0.086 12.8 17.4 0.038 14.0 12.2 2.4 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal Joubert PF15392.6 EGO52304.1 - 0.13 11.9 15.0 0.28 10.9 15.0 1.4 1 0 0 1 1 1 0 Joubert syndrome-associated TFIIA PF03153.13 EGO52304.1 - 1.4 8.8 38.7 0.24 11.3 34.2 1.9 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 EGO52304.1 - 2.5 7.4 18.4 0.28 10.6 7.3 2.2 2 0 0 2 2 2 0 SDA1 PLD_C PF12357.8 EGO52305.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase D C terminal MutS_V PF00488.21 EGO52306.1 - 2.6e-67 226.5 0.1 5.1e-67 225.6 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGO52306.1 - 1.4e-49 168.9 8.0 5.2e-49 167.1 8.0 2.0 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EGO52306.1 - 3.9e-21 75.4 0.0 9e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain I AAA_29 PF13555.6 EGO52306.1 - 0.033 13.9 0.0 0.14 12.0 0.0 2.1 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 EGO52306.1 - 0.15 11.6 1.0 1.4 8.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain RL10P_insert PF17777.1 EGO52307.1 - 3.2e-23 81.5 0.0 6.7e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EGO52307.1 - 4.1e-23 81.4 0.2 1e-22 80.1 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 EGO52307.1 - 4.9e-17 62.3 6.5 4.9e-17 62.3 6.5 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein WRNPLPNID PF15017.6 EGO52307.1 - 0.03 15.2 0.8 0.055 14.4 0.8 1.4 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Cytomega_UL84 PF06284.11 EGO52307.1 - 3.2 6.1 4.8 4.8 5.5 4.8 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein USP19_linker PF16602.5 EGO52307.1 - 3.7 8.1 5.6 28 5.3 0.3 2.5 3 0 0 3 3 3 0 Linker region of USP19 deubiquitinase WD40 PF00400.32 EGO52308.1 - 0.00031 21.5 0.7 8.9 7.4 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Acetyltransf_9 PF13527.7 EGO52308.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SWIRM-assoc_2 PF16496.5 EGO52308.1 - 2.7 6.8 9.5 4.3 6.1 9.5 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal BTB PF00651.31 EGO52309.1 - 2.2e-06 27.9 0.0 3.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DEAD PF00270.29 EGO52310.1 - 1.2e-17 64.2 0.0 4.1e-17 62.5 0.0 1.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO52310.1 - 1.7e-08 34.8 0.0 5.7e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO52310.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 EGO52310.1 - 0.028 15.0 0.0 0.085 13.5 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain zf-HC5HC2H_2 PF13832.6 EGO52311.1 - 3.7e-21 75.3 12.9 4e-19 68.8 1.4 4.1 3 0 0 3 3 3 3 PHD-zinc-finger like domain BAH PF01426.18 EGO52311.1 - 2e-18 66.4 0.0 4.2e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 EGO52311.1 - 3.3e-14 52.9 2.6 3.3e-14 52.9 2.6 5.1 5 1 0 5 5 5 1 PHD-like zinc-binding domain PHD PF00628.29 EGO52311.1 - 2.1e-11 43.5 53.7 4.9e-06 26.3 8.6 6.1 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.6 EGO52311.1 - 1.4e-08 34.2 5.0 1.4e-08 34.2 5.0 5.2 5 0 0 5 5 5 2 PHD-finger C1_2 PF03107.16 EGO52311.1 - 0.014 15.7 0.5 0.014 15.7 0.5 6.6 8 0 0 8 8 8 0 C1 domain GATA PF00320.27 EGO52311.1 - 4.4 7.0 12.7 0.29 10.8 0.8 4.3 4 0 0 4 4 4 0 GATA zinc finger ELM2 PF01448.24 EGO52311.1 - 7.9 7.3 7.7 5.2 7.9 0.1 3.6 3 0 0 3 3 3 0 ELM2 domain dCMP_cyt_deam_1 PF00383.23 EGO52313.1 - 4.4e-19 68.2 0.0 5.8e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGO52313.1 - 8.3e-15 54.7 0.0 1.1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC2 PF18772.1 EGO52313.1 - 0.0002 21.5 0.2 0.009 16.1 0.2 2.1 1 1 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 EGO52313.1 - 0.00047 20.3 0.0 0.27 11.3 0.0 2.1 2 0 0 2 2 2 2 Novel AID APOBEC clade 1 NAD2 PF18782.1 EGO52313.1 - 0.00051 20.2 0.1 0.024 14.8 0.1 2.0 1 1 0 1 1 1 1 Novel AID APOBEC clade 2 SNAD4 PF18750.1 EGO52313.1 - 0.006 16.7 0.0 0.047 13.8 0.0 2.0 1 1 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 EGO52313.1 - 0.013 15.4 0.3 0.34 10.8 0.3 2.0 1 1 0 1 1 1 0 APOBEC-like N-terminal domain Bd3614-deam PF14439.6 EGO52313.1 - 0.052 13.6 0.3 0.27 11.3 0.2 2.0 1 1 1 2 2 2 0 Bd3614-like deaminase DnaJ_C PF01556.18 EGO52314.1 - 1e-37 129.5 0.1 1.4e-37 129.1 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGO52314.1 - 3.7e-26 91.0 1.8 6.8e-26 90.2 1.8 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGO52314.1 - 1.4e-16 60.6 18.7 2.8e-16 59.6 18.7 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EGO52314.1 - 0.25 11.4 10.4 0.99 9.5 3.0 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2614 PF11023.8 EGO52314.1 - 0.3 11.2 6.3 1.7 8.7 1.3 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain zinc-ribbons_6 PF07191.12 EGO52314.1 - 0.59 10.2 8.8 3.2 7.8 2.4 2.4 1 1 1 2 2 2 0 zinc-ribbons zinc_ribbon_9 PF14369.6 EGO52314.1 - 0.72 10.2 3.0 32 4.9 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon Anti-TRAP PF15777.5 EGO52314.1 - 1.4 9.0 17.2 0.47 10.4 3.2 2.7 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 EGO52314.1 - 5 7.2 11.1 5.1e+02 0.8 11.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon Abhydrolase_1 PF00561.20 EGO52315.1 - 3.2e-14 53.2 0.0 5.8e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO52315.1 - 2e-07 30.6 0.0 3.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGO52315.1 - 0.00024 21.8 0.9 0.0066 17.1 0.9 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EGO52315.1 - 0.005 16.5 0.0 0.017 14.7 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EGO52315.1 - 0.016 14.7 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 EGO52315.1 - 0.021 13.6 0.0 0.034 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Esterase PF00756.20 EGO52315.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Methyltransf_7 PF03492.15 EGO52315.1 - 0.11 11.6 0.0 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase SNARE_assoc PF09335.11 EGO52317.1 - 1.7e-12 47.8 8.2 1.7e-12 47.8 8.2 2.4 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF1700 PF08006.11 EGO52317.1 - 1.5 8.4 4.4 2.4 7.7 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF1771 PF08590.10 EGO52318.1 - 1.3e-14 54.3 9.8 2.7e-14 53.3 9.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf-CCCH_2 PF14608.6 EGO52318.1 - 1.7e-05 25.1 3.8 0.057 13.9 0.1 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Smr PF01713.21 EGO52318.1 - 2.2e-05 24.7 0.0 6.2e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.24 EGO52318.1 - 0.00029 20.7 2.3 0.0046 16.8 0.3 2.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGO52318.1 - 0.001 19.1 8.8 0.1 12.7 0.7 3.2 2 1 0 2 2 2 2 Zinc finger domain HBS1_N PF08938.10 EGO52318.1 - 0.026 14.8 0.2 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 HBS1 N-terminus zf-CCCH_4 PF18044.1 EGO52318.1 - 0.26 11.1 12.9 1.3 8.9 1.4 3.5 2 2 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EGO52318.1 - 0.51 10.6 4.2 3.9 7.7 4.3 2.0 1 1 0 1 1 1 0 Zinc-finger containing family Torus PF16131.5 EGO52318.1 - 1.5 9.5 3.7 14 6.4 0.2 2.4 1 1 1 2 2 2 0 Torus domain Cupin_8 PF13621.6 EGO52319.1 - 2.8e-19 69.8 0.5 3e-18 66.5 0.5 2.0 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EGO52319.1 - 1.4e-09 38.4 0.1 5.5e-09 36.5 0.1 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 EGO52319.1 - 2.9e-05 23.9 0.3 7e-05 22.6 0.3 1.7 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.12 EGO52319.1 - 0.0083 15.6 0.0 0.039 13.4 0.0 1.9 2 0 0 2 2 2 1 Cupin superfamily protein F-box PF00646.33 EGO52319.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 F-box domain DEAD PF00270.29 EGO52321.1 - 1.1e-45 155.5 0.8 1.9e-45 154.7 0.8 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO52321.1 - 7.8e-32 109.9 0.3 8.8e-31 106.5 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO52321.1 - 4e-06 26.9 0.0 6.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EGO52321.1 - 0.00036 20.3 0.1 0.00073 19.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGO52321.1 - 0.0012 19.2 0.8 0.0077 16.6 0.3 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGO52321.1 - 0.024 14.9 0.7 0.16 12.3 0.7 2.3 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 EGO52321.1 - 0.025 13.9 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit IL17R_D_N PF16742.5 EGO52321.1 - 0.094 12.8 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D tRNA-synt_1b PF00579.25 EGO52321.1 - 0.11 11.8 0.0 0.51 9.6 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) fragilysinNterm PF16376.5 EGO52321.1 - 0.12 12.2 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin RRM_1 PF00076.22 EGO52322.1 - 2.5e-16 59.2 0.0 4.6e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EGO52322.1 - 7.4e-06 26.4 17.0 7.4e-06 26.4 17.0 4.3 3 2 2 5 5 5 1 C-terminal duplication domain of Friend of PRMT1 DUF1932 PF09130.11 EGO52323.1 - 8.2e-20 70.6 0.0 1.8e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 EGO52323.1 - 6.9e-08 32.8 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGO52323.1 - 1.1e-07 32.4 0.3 3.7e-07 30.6 0.3 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EGO52323.1 - 0.00088 18.7 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 EGO52323.1 - 0.0016 18.3 0.3 0.0027 17.6 0.3 1.4 1 0 0 1 1 1 1 Rossmann-like domain IlvN PF07991.12 EGO52323.1 - 0.0041 16.7 0.0 0.0067 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 EGO52323.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AATF-Che1 PF13339.6 EGO52324.1 - 0.013 16.2 0.5 0.93 10.2 0.0 2.9 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor DUF2673 PF10880.8 EGO52325.1 - 0.13 12.4 0.7 0.2 11.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) F-box-like PF12937.7 EGO52326.1 - 0.00043 20.1 0.0 0.00095 19.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF2415 PF10313.9 EGO52326.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) AP_endonuc_2 PF01261.24 EGO52327.1 - 6.4e-34 117.2 0.0 8.5e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.12 EGO52328.1 - 6.3e-42 142.5 0.8 1.1e-41 141.7 0.8 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 EGO52328.1 - 7.1e-09 35.4 0.0 4.7e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.11 EGO52328.1 - 3.7e-08 33.4 0.0 1.4e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Mad3_BUB1_I_2 PF17014.5 EGO52328.1 - 0.0015 18.7 0.0 0.0035 17.5 0.0 1.5 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Pkinase_Tyr PF07714.17 EGO52328.1 - 0.037 13.3 0.1 0.11 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Enolase_C PF00113.22 EGO52330.1 - 1.8e-152 506.7 0.1 2.3e-152 506.4 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EGO52330.1 - 4e-58 195.2 0.0 7.7e-58 194.3 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EGO52330.1 - 2.9e-06 27.0 0.0 5.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EGO52330.1 - 0.0012 18.0 0.2 0.056 12.6 0.1 2.8 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus ERAP1_C PF11838.8 EGO52332.1 - 4.7e-91 305.6 0.0 2.1e-90 303.4 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EGO52332.1 - 6.1e-86 287.5 0.3 1e-85 286.7 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EGO52332.1 - 1.7e-54 184.9 1.0 8.1e-54 182.6 0.5 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF4110 PF13422.6 EGO52333.1 - 8.3e-32 109.1 0.3 8.3e-32 109.1 0.3 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 EGO52333.1 - 3e-26 91.2 12.3 2.4e-05 24.2 0.0 6.3 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGO52333.1 - 2.5e-24 85.0 12.4 5.6e-09 36.1 0.1 5.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EGO52333.1 - 1.8e-18 66.1 1.6 1.6e-06 28.0 0.0 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 EGO52333.1 - 5.3e-17 61.4 2.8 2.9e-06 27.4 0.1 5.5 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 EGO52333.1 - 2.8e-15 55.6 0.9 4.3e-05 23.0 0.0 4.8 4 1 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 EGO52333.1 - 5e-15 54.8 0.7 0.057 13.4 0.0 6.1 6 1 0 6 6 6 4 Kelch motif BUD22 PF09073.10 EGO52333.1 - 0.0031 16.9 14.9 0.0031 16.9 14.9 2.3 2 0 0 2 2 2 1 BUD22 WLM PF08325.10 EGO52334.1 - 1.3e-14 54.7 9.6 1.8e-14 54.3 4.5 3.3 2 1 1 3 3 3 1 WLM domain DUF45 PF01863.17 EGO52334.1 - 7.1e-08 32.7 0.6 2.5e-07 31.0 0.6 1.9 1 0 0 1 1 1 1 Protein of unknown function DUF45 Thioredoxin PF00085.20 EGO52337.1 - 2.4e-62 207.3 5.4 6.8e-31 106.3 0.3 3.7 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 EGO52337.1 - 2.5e-50 170.9 2.4 1.1e-39 136.3 0.3 3.4 2 2 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGO52337.1 - 1.4e-09 38.1 0.1 0.018 15.4 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 EGO52337.1 - 3e-09 36.9 0.1 0.00065 19.8 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGO52337.1 - 2.3e-08 34.4 1.2 0.00063 20.2 0.1 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EGO52337.1 - 7.8e-08 32.0 3.3 0.034 13.5 0.0 3.9 3 1 1 4 4 4 2 OST3 / OST6 family, transporter family Redoxin PF08534.10 EGO52337.1 - 3.9e-07 29.9 6.0 0.0012 18.6 0.0 3.6 4 0 0 4 4 4 2 Redoxin AhpC-TSA PF00578.21 EGO52337.1 - 5.5e-07 29.5 4.1 0.011 15.6 0.1 3.5 2 1 0 3 3 3 2 AhpC/TSA family Calsequestrin PF01216.17 EGO52337.1 - 7.3e-06 25.3 2.9 7.3e-06 25.3 2.9 2.0 2 1 0 2 2 2 1 Calsequestrin ERp29_N PF07912.13 EGO52337.1 - 4.1e-05 23.7 0.8 2 8.6 0.0 4.0 3 1 0 3 3 3 2 ERp29, N-terminal domain DSBA PF01323.20 EGO52337.1 - 0.023 14.5 0.8 3.6 7.3 0.1 3.1 3 1 0 3 3 3 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EGO52337.1 - 0.026 14.7 4.3 4 7.6 0.0 4.1 3 1 0 3 3 3 0 Thioredoxin Thioredoxin_3 PF13192.6 EGO52337.1 - 0.061 13.4 0.1 0.32 11.1 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin domain D5_N PF08706.11 EGO52337.1 - 0.13 12.5 0.1 0.28 11.4 0.1 1.6 1 0 0 1 1 1 0 D5 N terminal like Glutaredoxin PF00462.24 EGO52337.1 - 0.42 10.9 3.5 5.4 7.3 0.5 3.4 3 1 0 3 3 3 0 Glutaredoxin CENP-Q PF13094.6 EGO52338.1 - 0.0067 16.6 0.1 0.0081 16.4 0.1 1.1 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit zf-HIT PF04438.16 EGO52339.1 - 3.6e-09 36.3 5.6 5.5e-09 35.7 5.6 1.3 1 0 0 1 1 1 1 HIT zinc finger Nif11 PF07862.11 EGO52339.1 - 0.083 13.2 0.9 0.37 11.1 0.0 2.4 3 0 0 3 3 3 0 Nif11 domain FSA_C PF10479.9 EGO52339.1 - 0.89 7.6 2.9 1.1 7.3 2.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mon1 PF03164.14 EGO52340.1 - 2.5e-150 501.1 0.0 3e-150 500.8 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.14 EGO52341.1 - 1.1e-117 392.6 0.0 5.8e-117 390.2 0.0 2.2 2 0 0 2 2 2 1 Dopey, N-terminal HEAT_EZ PF13513.6 EGO52341.1 - 0.041 14.4 3.5 11 6.7 0.0 5.4 5 0 0 5 5 5 0 HEAT-like repeat Methyltransf_15 PF09445.10 EGO52342.1 - 2.9e-60 202.6 0.0 4.1e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 EGO52342.1 - 0.022 14.4 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.16 EGO52342.1 - 0.039 13.7 0.0 0.094 12.5 0.0 1.5 2 0 0 2 2 2 0 Met-10+ like-protein Methyltransf_18 PF12847.7 EGO52342.1 - 0.065 13.2 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EGO52342.1 - 0.093 12.4 0.0 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 95 FXR_C1 PF16096.5 EGO52342.1 - 1.4 9.2 5.3 5.5 7.3 3.6 2.2 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 GRASP55_65 PF04495.14 EGO52343.1 - 1.6e-48 164.5 0.0 2.8e-47 160.5 0.0 2.3 2 1 1 3 3 3 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EGO52343.1 - 0.1 12.5 0.0 21 5.1 0.0 2.4 2 0 0 2 2 2 0 PDZ domain DAD PF02109.16 EGO52344.1 - 3.2e-36 124.0 0.1 4.7e-36 123.4 0.1 1.2 1 0 0 1 1 1 1 DAD family TrbL PF04610.14 EGO52344.1 - 0.021 14.6 1.1 0.028 14.2 1.1 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Mucin PF01456.17 EGO52344.1 - 0.066 13.2 24.2 0.12 12.3 24.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF202 PF02656.15 EGO52345.1 - 1.4e-05 25.5 3.0 3.3e-05 24.2 1.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Zn_clus PF00172.18 EGO52346.1 - 3.1e-07 30.4 7.9 4.8e-07 29.8 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prot_inhib_II PF02428.15 EGO52346.1 - 0.35 11.4 3.3 0.62 10.5 3.3 1.4 1 0 0 1 1 1 0 Potato type II proteinase inhibitor family Pkinase PF00069.25 EGO52350.1 - 1.1e-70 238.0 0.0 2.4e-70 236.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO52350.1 - 2.3e-33 115.6 0.0 1.1e-31 110.1 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO52350.1 - 0.00056 19.3 0.6 0.48 9.7 0.1 2.7 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGO52350.1 - 0.013 14.3 0.7 0.024 13.4 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 EGO52350.1 - 0.015 14.9 0.5 0.033 13.8 0.5 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EGO52350.1 - 0.017 15.1 1.1 0.082 12.8 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family AAA_12 PF13087.6 EGO52351.1 - 2.3e-23 82.8 0.0 1.9e-12 47.2 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_11 PF13086.6 EGO52351.1 - 2e-22 80.3 0.1 4.1e-21 76.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGO52351.1 - 1.9e-07 31.5 0.0 2.9e-06 27.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGO52351.1 - 4.6e-07 29.7 0.0 1.4e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EGO52351.1 - 0.0025 17.6 0.0 0.51 10.0 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EGO52351.1 - 0.0072 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 EGO52351.1 - 0.042 13.8 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 EGO52351.1 - 0.15 11.6 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Dyp_perox PF04261.12 EGO52352.1 - 3.9e-08 32.7 0.0 9.5e-07 28.1 0.0 2.7 3 0 0 3 3 3 1 Dyp-type peroxidase family DUF1929 PF09118.11 EGO52353.1 - 3.5e-23 81.7 0.1 8e-23 80.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.25 EGO52353.1 - 2.1e-18 66.7 0.2 5.5e-18 65.3 0.2 1.8 1 0 0 1 1 1 1 F5/8 type C domain Kelch_6 PF13964.6 EGO52353.1 - 3.4e-17 62.1 0.9 2.4e-05 24.5 0.0 4.9 4 2 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EGO52353.1 - 1.2e-14 53.6 0.7 2.5e-05 23.8 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 EGO52353.1 - 2.3e-10 40.3 2.5 6.2e-05 22.9 0.0 4.3 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EGO52353.1 - 7.7e-10 38.4 0.0 0.021 14.8 0.0 4.5 3 1 0 3 3 3 3 Kelch motif Glyoxal_oxid_N PF07250.11 EGO52353.1 - 3.7e-07 29.6 0.2 0.016 14.4 0.1 2.7 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus Laminin_N PF00055.17 EGO52353.1 - 0.0076 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Laminin N-terminal (Domain VI) Kelch_5 PF13854.6 EGO52353.1 - 0.016 15.1 0.8 3.6 7.7 0.0 3.5 3 0 0 3 3 3 0 Kelch motif XRCC1_N PF01834.16 EGO52353.1 - 0.027 14.5 0.1 0.054 13.5 0.1 1.4 1 0 0 1 1 1 0 XRCC1 N terminal domain Kelch_3 PF13415.6 EGO52353.1 - 0.13 12.6 3.0 7.6 6.9 0.0 4.7 4 2 0 4 4 4 0 Galactose oxidase, central domain WD40 PF00400.32 EGO52354.1 - 4.4e-13 49.5 7.9 0.11 13.4 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat YL1 PF05764.13 EGO52354.1 - 2.6 8.1 17.6 0.95 9.5 10.8 2.1 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 EGO52354.1 - 4.5 5.4 7.9 6.9 4.8 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 EGO52355.1 - 5.2e-11 42.1 33.6 3.7e-08 32.7 11.4 3.0 3 0 0 3 3 3 3 Major Facilitator Superfamily zf-met PF12874.7 EGO52357.1 - 3.2e-05 24.2 1.0 0.41 11.1 0.1 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGO52357.1 - 0.0086 16.3 3.9 0.3 11.4 0.2 3.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EGO52357.1 - 0.022 15.6 16.2 0.23 12.4 0.3 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-LYAR PF08790.11 EGO52357.1 - 0.14 12.1 2.2 12 5.9 0.1 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.26 EGO52357.1 - 0.21 12.1 0.3 0.21 12.1 0.3 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type Fungal_trans PF04082.18 EGO52358.1 - 8.1e-19 67.7 0.5 2e-18 66.4 0.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO52358.1 - 9.5e-10 38.4 11.8 1.9e-09 37.5 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep57_CLD_2 PF14197.6 EGO52358.1 - 0.39 10.8 2.5 0.66 10.1 2.5 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Brr6_like_C_C PF10104.9 EGO52359.1 - 6.2e-42 142.5 1.6 8e-42 142.2 1.6 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Med26 PF08711.11 EGO52360.1 - 1.5e-10 40.9 0.0 3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Rrn6 PF10214.9 EGO52360.1 - 7.1 5.0 10.1 1.5 7.2 6.1 1.8 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Amelogenin PF02948.15 EGO52362.1 - 0.24 12.0 25.0 0.89 10.2 12.9 2.5 1 1 1 2 2 2 0 Amelogenin Myc_N PF01056.18 EGO52365.1 - 0.16 11.8 13.0 0.057 13.3 7.8 2.2 1 1 1 2 2 2 0 Myc amino-terminal region DUF3470 PF11953.8 EGO52365.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3470) Astro_capsid_p PF12226.8 EGO52365.1 - 0.19 10.8 7.3 0.31 10.2 7.3 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 EGO52365.1 - 4 5.5 13.9 7.5 4.6 13.9 1.5 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 EGO52365.1 - 6.8 6.7 8.3 15 5.6 8.3 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Tyrosinase PF00264.20 EGO52366.1 - 1.9e-49 169.0 0.4 2.4e-49 168.6 0.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Myb_DNA-binding PF00249.31 EGO52367.1 - 1.1e-34 118.4 9.1 8.9e-13 48.2 1.6 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO52367.1 - 5.9e-30 103.3 10.3 1.9e-13 50.5 0.8 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 EGO52367.1 - 3.9e-05 23.6 2.3 0.29 11.3 0.3 3.3 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 EGO52367.1 - 0.0014 18.7 0.0 0.71 10.1 0.0 2.8 3 0 0 3 3 3 2 Rap1 Myb domain Myb_DNA-bind_7 PF15963.5 EGO52367.1 - 0.0097 15.8 0.0 0.38 10.7 0.0 2.4 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EGO52367.1 - 0.13 12.6 8.1 0.62 10.5 0.3 3.7 2 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF3439 PF11921.8 EGO52367.1 - 1.8 8.6 23.8 0.43 10.6 12.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF3433 PF11915.8 EGO52368.1 - 0.095 13.2 0.5 0.22 12.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) PQ-loop PF04193.14 EGO52369.1 - 4.7e-39 132.0 14.7 6.8e-21 73.8 0.3 3.3 3 1 1 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.18 EGO52369.1 - 0.014 16.2 0.2 3 8.7 0.0 2.4 2 0 0 2 2 2 0 ER lumen protein retaining receptor SLAIN PF15301.6 EGO52369.1 - 0.72 9.0 6.9 0.98 8.6 6.9 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family S1-P1_nuclease PF02265.16 EGO52370.1 - 8.1e-78 261.7 0.0 9.3e-78 261.5 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease CDP-OH_P_transf PF01066.21 EGO52372.1 - 8.8e-13 48.8 0.7 8.8e-13 48.8 0.7 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NFACT-C PF11923.8 EGO52373.1 - 1.3e-38 131.2 0.2 1.3e-38 131.2 0.2 3.7 4 0 0 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 EGO52373.1 - 3.3e-34 118.4 8.4 3.3e-34 118.4 8.4 2.5 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 EGO52373.1 - 3.8e-33 114.4 0.0 8.6e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain eIF-5a PF01287.20 EGO52374.1 - 1.8e-07 31.2 0.1 2.7e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Peptidase_C1_2 PF03051.15 EGO52375.1 - 2.2e-153 511.2 0.0 2.5e-153 511.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EGO52375.1 - 3.7e-08 33.7 0.0 0.00088 19.4 0.0 2.6 3 0 0 3 3 3 2 Papain family cysteine protease DUF3818 PF12825.7 EGO52381.1 - 4.1e-131 437.0 7.6 8.2e-131 436.0 7.6 1.5 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EGO52381.1 - 2.4e-39 134.3 1.4 5e-39 133.3 1.4 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 EGO52381.1 - 1.7e-12 47.3 4.1 2.1e-12 47.0 0.0 2.9 3 0 0 3 3 3 1 PX domain GFD1 PF17331.2 EGO52381.1 - 0.13 12.5 1.4 0.39 10.9 1.4 1.8 1 0 0 1 1 1 0 GFD1 mRNA transport factor FAD_binding_2 PF00890.24 EGO52382.1 - 6.1e-123 411.0 3.9 7.6e-123 410.7 3.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EGO52382.1 - 1.9e-45 154.0 0.2 2.9e-45 153.4 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EGO52382.1 - 1.6e-06 27.6 0.3 0.00092 18.5 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGO52382.1 - 2.9e-05 23.4 1.0 0.012 14.7 1.7 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 EGO52382.1 - 3.4e-05 23.2 0.2 0.028 13.7 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 EGO52382.1 - 0.002 17.4 0.6 0.0058 15.9 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EGO52382.1 - 0.068 12.7 1.4 0.17 11.5 1.4 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EGO52382.1 - 0.085 11.5 0.8 0.3 9.7 0.4 2.1 2 0 0 2 2 2 0 HI0933-like protein DUF3405 PF11885.8 EGO52384.1 - 3.7e-229 761.6 4.7 4.6e-229 761.3 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) EMP24_GP25L PF01105.24 EGO52385.1 - 1e-44 152.7 0.1 1.1e-44 152.5 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SpoU_methylase PF00588.19 EGO52385.1 - 0.048 13.8 0.0 0.9 9.7 0.0 2.1 1 1 1 2 2 2 0 SpoU rRNA Methylase family Arf PF00025.21 EGO52386.1 - 1.3e-78 262.4 0.1 1.6e-78 262.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGO52386.1 - 2e-14 53.8 0.0 2.8e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGO52386.1 - 2.3e-14 53.3 0.0 2.8e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGO52386.1 - 3.2e-13 49.6 1.4 1.7e-09 37.3 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGO52386.1 - 1.2e-12 47.7 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGO52386.1 - 1.5e-10 40.9 0.0 1.8e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGO52386.1 - 9.2e-06 25.7 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EGO52386.1 - 0.0071 15.7 0.4 0.016 14.5 0.4 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase TPM_phosphatase PF04536.14 EGO52386.1 - 0.086 13.0 0.1 0.15 12.2 0.1 1.5 1 1 0 1 1 1 0 TPM domain E1-E2_ATPase PF00122.20 EGO52387.1 - 2.8e-50 170.3 0.4 2.8e-50 170.3 0.4 2.3 3 0 0 3 3 3 1 E1-E2 ATPase HMA PF00403.26 EGO52387.1 - 5.1e-49 164.6 3.6 1e-13 51.5 0.3 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 EGO52387.1 - 1.7e-39 136.3 1.5 4.2e-39 135.0 1.5 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGO52387.1 - 6.8e-07 29.3 0.9 4.7e-05 23.3 0.5 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGO52387.1 - 0.029 14.8 0.1 0.11 12.9 0.1 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGO52387.1 - 0.13 12.4 0.1 0.5 10.4 0.1 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase CDCA PF18484.1 EGO52387.1 - 0.64 9.9 2.4 5.3 6.9 0.0 3.4 3 1 1 4 4 4 0 Cadmium carbonic anhydrase repeat PCI PF01399.27 EGO52388.1 - 0.00033 21.1 0.1 0.0021 18.5 0.0 2.1 2 0 0 2 2 2 1 PCI domain ANAPC_CDC26 PF10471.9 EGO52388.1 - 9.7 7.1 13.8 1.1 10.1 5.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 RGS PF00615.19 EGO52389.1 - 1.3e-11 44.8 0.0 2.8e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF308 PF03729.13 EGO52389.1 - 4.4 7.7 7.4 0.1 12.9 0.7 1.7 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Ribosomal_L31e PF01198.19 EGO52390.1 - 7.2e-40 135.1 1.5 9.8e-40 134.7 1.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e UQ_con PF00179.26 EGO52391.1 - 4.8e-08 32.8 0.0 5.6e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.25 EGO52392.1 - 6.4e-58 196.2 0.0 8.3e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO52392.1 - 2.2e-29 102.5 0.0 3.4e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO52392.1 - 2.4e-07 30.3 0.0 3.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGO52392.1 - 6.8e-05 22.9 0.0 0.37 10.7 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGO52392.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SprT-like PF10263.9 EGO52393.1 - 5.8e-18 64.8 0.0 5.8e-18 64.8 0.0 2.4 2 0 0 2 2 2 1 SprT-like family Androgen_recep PF02166.16 EGO52393.1 - 0.23 10.3 8.4 0.39 9.5 8.4 1.4 1 0 0 1 1 1 0 Androgen receptor F-box-like PF12937.7 EGO52394.1 - 8.2e-09 35.2 0.1 2.1e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO52394.1 - 3.8e-07 29.8 0.5 8.7e-07 28.7 0.5 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGO52394.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 F-box DUF1772 PF08592.11 EGO52397.1 - 1e-21 77.7 0.8 3e-21 76.2 0.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) EGF_CA PF07645.15 EGO52398.1 - 4.6 7.5 8.0 9.3 6.5 6.2 2.1 1 1 1 2 2 2 0 Calcium-binding EGF domain Pyr_redox_2 PF07992.14 EGO52399.1 - 4.7e-52 177.0 1.7 5.5e-52 176.8 1.7 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO52399.1 - 2e-19 70.0 1.6 5.4e-18 65.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO52399.1 - 5.5e-19 68.5 3.6 7.2e-17 61.7 1.2 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EGO52399.1 - 2.5e-06 27.9 0.2 0.0008 19.8 0.1 2.6 2 2 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 EGO52399.1 - 2.9e-05 23.4 0.1 0.00072 18.9 0.0 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EGO52399.1 - 6e-05 23.2 0.1 0.071 13.4 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO52399.1 - 0.00011 22.0 0.3 3.4 7.2 0.0 3.3 2 1 1 3 3 3 3 FAD dependent oxidoreductase GIDA PF01134.22 EGO52399.1 - 0.00022 20.5 4.5 0.41 9.7 0.4 4.2 3 2 1 4 4 4 2 Glucose inhibited division protein A K_oxygenase PF13434.6 EGO52399.1 - 0.00052 19.3 0.2 0.046 12.9 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 EGO52399.1 - 0.0018 17.7 0.1 0.042 13.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGO52399.1 - 0.0021 17.4 2.6 2.8 7.1 0.0 3.1 2 1 1 3 3 3 2 FAD binding domain HI0933_like PF03486.14 EGO52399.1 - 0.006 15.3 0.9 1.2 7.7 0.1 3.2 2 1 1 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 EGO52399.1 - 0.0077 15.4 7.7 0.12 11.5 0.5 3.2 3 1 1 4 4 4 2 FAD binding domain Trp_halogenase PF04820.14 EGO52399.1 - 0.015 14.2 0.1 0.38 9.6 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.20 EGO52399.1 - 0.021 14.9 0.5 9.3 6.3 0.1 3.0 3 1 1 4 4 4 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 EGO52400.1 - 3.6e-32 111.1 1.4 5.7e-32 110.4 1.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO52400.1 - 2.8e-13 51.1 0.0 4.9e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO52400.1 - 2.8e-05 24.0 0.0 0.0001 22.1 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 EGO52400.1 - 0.014 15.7 0.1 0.026 14.8 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 EGO52400.1 - 0.16 11.2 5.4 0.22 10.8 4.8 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-CCCH PF00642.24 EGO52401.1 - 8.9e-18 63.7 33.2 8.8e-07 28.7 0.4 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGO52401.1 - 9.5e-18 63.6 34.3 1.5e-06 28.1 1.9 5.4 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 EGO52401.1 - 6.4e-09 36.5 30.6 0.00044 20.9 0.7 5.7 1 1 5 6 6 6 4 Torus domain zf-CCCH_4 PF18044.1 EGO52401.1 - 4.3e-06 26.4 34.9 1.3e-05 24.9 0.4 5.5 5 1 0 5 5 5 3 CCCH-type zinc finger SUIM_assoc PF16619.5 EGO52401.1 - 0.048 13.7 1.3 0.1 12.7 0.1 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Activator_LAG-3 PF11498.8 EGO52401.1 - 0.052 12.5 12.4 0.073 12.0 12.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 zf-CCCH_3 PF15663.5 EGO52401.1 - 0.44 10.8 14.3 7.1 6.9 0.5 3.4 2 1 1 3 3 3 0 Zinc-finger containing family FAM27 PF15832.5 EGO52401.1 - 1.2 9.7 8.2 2.7 8.6 8.2 1.6 1 0 0 1 1 1 0 FAM27 D and E protein family DUF3043 PF11241.8 EGO52401.1 - 5.5 7.0 7.3 8.8 6.3 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF1776 PF08643.10 EGO52402.1 - 7.4e-119 396.5 0.0 9.6e-119 396.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Methyltransf_25 PF13649.6 EGO52403.1 - 5.1e-15 56.0 0.2 1.6e-14 54.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO52403.1 - 3.5e-13 49.6 0.0 4.9e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO52403.1 - 2.5e-11 44.2 0.0 5.5e-11 43.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO52403.1 - 6.5e-11 42.7 0.1 6.4e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGO52403.1 - 1.9e-05 24.3 0.0 2.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EGO52403.1 - 9.9e-05 22.2 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EGO52403.1 - 0.00015 21.5 0.0 0.003 17.3 0.0 2.4 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.18 EGO52403.1 - 0.00037 19.9 0.0 0.00094 18.6 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EGO52403.1 - 0.00038 20.5 0.0 0.00059 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGO52403.1 - 0.0026 17.5 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SnoaL_4 PF13577.6 EGO52403.1 - 0.0063 16.6 1.0 0.032 14.4 0.0 2.2 1 1 1 3 3 3 1 SnoaL-like domain DREV PF05219.12 EGO52403.1 - 0.0088 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.13 EGO52403.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 EGO52403.1 - 0.02 13.9 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.7 EGO52403.1 - 0.041 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Amidase PF01425.21 EGO52404.1 - 1.3e-88 297.9 0.0 2.2e-88 297.2 0.0 1.3 1 1 0 1 1 1 1 Amidase UPF0180 PF03698.13 EGO52404.1 - 0.048 13.8 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) WD40 PF00400.32 EGO52405.1 - 1e-14 54.6 7.5 0.0014 19.4 0.0 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO52405.1 - 7.2e-14 51.9 0.0 7.9e-05 22.9 0.0 4.6 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGO52405.1 - 0.00057 19.8 0.1 0.15 11.9 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 EGO52405.1 - 0.0014 17.7 0.0 0.2 10.6 0.0 2.9 2 1 1 3 3 3 1 Coatomer WD associated region HIRA_B PF09453.10 EGO52405.1 - 0.0029 17.4 0.1 0.0029 17.4 0.1 2.4 3 0 0 3 3 3 1 HIRA B motif TMEM171 PF15471.6 EGO52405.1 - 8.5 5.3 15.1 4.9 6.0 2.6 2.4 2 0 0 2 2 2 0 Transmembrane protein family 171 DUF4185 PF13810.6 EGO52406.1 - 0.0036 16.6 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) ABC_tran PF00005.27 EGO52407.1 - 1.1e-52 178.2 0.1 2.6e-30 105.7 0.1 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGO52407.1 - 1.6e-38 133.0 26.7 3.8e-27 95.6 11.0 3.6 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EGO52407.1 - 1.2e-08 34.6 2.7 0.00063 19.2 0.6 4.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGO52407.1 - 0.00053 20.4 2.5 0.072 13.5 0.1 3.2 3 0 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 EGO52407.1 - 0.00096 19.2 0.3 0.077 13.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 EGO52407.1 - 0.00098 18.3 0.0 0.19 10.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 EGO52407.1 - 0.0012 18.5 0.0 0.33 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGO52407.1 - 0.0023 17.6 0.9 2.2 8.1 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGO52407.1 - 0.0063 16.4 0.3 1.9 8.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EGO52407.1 - 0.019 15.5 0.4 2.2 8.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EGO52407.1 - 0.026 14.3 0.9 6.8 6.4 0.2 3.7 3 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 EGO52407.1 - 0.034 13.9 0.0 1.3 8.8 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 EGO52407.1 - 0.036 13.8 0.2 2.6 7.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 EGO52407.1 - 0.04 13.2 0.1 0.67 9.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EGO52407.1 - 0.14 12.4 3.8 24 5.2 0.4 3.3 2 1 0 2 2 2 0 AAA domain GAIN_A PF18619.1 EGO52407.1 - 0.15 12.3 0.3 0.43 10.8 0.3 1.8 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A DUF87 PF01935.17 EGO52407.1 - 0.31 11.1 4.4 1.4 8.9 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain dCMP_cyt_deam_1 PF00383.23 EGO52408.1 - 2.4e-11 43.4 0.9 3.6e-10 39.6 0.9 2.1 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EGO52408.1 - 1.4e-05 25.3 0.8 0.011 15.9 0.0 3.0 3 0 0 3 3 3 2 Cytidine and deoxycytidylate deaminase zinc-binding region FYVE PF01363.21 EGO52409.1 - 2.2e-21 75.8 0.7 4e-21 74.9 0.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EGO52409.1 - 0.004 17.4 1.0 0.008 16.4 1.0 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger Elf1 PF05129.13 EGO52409.1 - 0.28 11.2 4.3 0.45 10.6 2.0 2.0 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Prok-RING_2 PF14445.6 EGO52409.1 - 0.33 11.1 2.7 0.68 10.1 2.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 adh_short PF00106.25 EGO52410.1 - 9.6e-34 116.5 0.1 1.6e-33 115.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO52410.1 - 7.1e-31 107.6 2.2 6.2e-30 104.5 0.3 2.2 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO52410.1 - 3.3e-07 30.4 0.3 4.8e-07 29.9 0.3 1.2 1 0 0 1 1 1 1 KR domain PQ-loop PF04193.14 EGO52412.1 - 3.3e-23 81.2 4.7 4.8e-14 51.9 1.7 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF4805 PF16063.5 EGO52412.1 - 0.15 11.4 2.8 0.25 10.7 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) DUF3426 PF11906.8 EGO52412.1 - 0.5 10.5 2.5 1.8 8.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3426) Sulfatase PF00884.23 EGO52413.1 - 2.7e-56 191.2 0.0 3.5e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 EGO52413.1 - 9.1e-25 86.2 1.1 1.8e-24 85.3 0.6 1.8 2 0 0 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 EGO52413.1 - 1.1e-07 31.8 0.1 8.7e-07 28.8 0.1 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EGO52413.1 - 0.036 12.7 0.0 0.056 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF4976 PF16347.5 EGO52413.1 - 0.07 13.4 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Med8 PF10232.9 EGO52414.1 - 3.2e-34 118.5 3.6 5e-34 117.9 3.6 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 SSXT PF05030.12 EGO52414.1 - 0.0048 16.5 0.1 0.0082 15.8 0.1 1.4 1 0 0 1 1 1 1 SSXT protein (N-terminal region) PBP1_TM PF14812.6 EGO52414.1 - 0.1 13.0 11.6 1.8 9.0 4.2 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SesA PF17107.5 EGO52414.1 - 0.12 12.5 0.3 0.26 11.5 0.3 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Urb2 PF10441.9 EGO52414.1 - 0.24 11.3 1.5 0.71 9.8 1.5 1.7 1 1 0 1 1 1 0 Urb2/Npa2 family CENP-B_dimeris PF09026.10 EGO52414.1 - 0.72 10.3 16.0 0.63 10.5 3.5 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Acyl_transf_3 PF01757.22 EGO52417.1 - 1.9e-32 112.7 13.0 3e-32 112.0 13.0 1.3 1 1 0 1 1 1 1 Acyltransferase family GFA PF04828.14 EGO52418.1 - 3.2e-16 59.4 1.4 5.9e-16 58.6 1.4 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNase_P_p30 PF01876.16 EGO52420.1 - 1.8e-61 207.3 0.0 2.5e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 DUF5562 PF17717.1 EGO52420.1 - 1.2 9.0 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5562) Spt20 PF12090.8 EGO52420.1 - 2.6 7.6 15.6 3.3 7.3 15.6 1.1 1 0 0 1 1 1 0 Spt20 family Coilin_N PF15862.5 EGO52420.1 - 9.9 6.0 9.0 15 5.3 9.0 1.2 1 0 0 1 1 1 0 Coilin N-terminus zinc_ribbon_15 PF17032.5 EGO52421.1 - 7.8e-06 26.5 0.2 1.1e-05 26.1 0.2 1.2 1 0 0 1 1 1 1 zinc-ribbon family DUF155 PF02582.14 EGO52422.1 - 1.3e-54 184.9 0.1 2.4e-54 184.1 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ECSCR PF15820.5 EGO52422.1 - 0.032 14.0 0.1 0.072 12.9 0.1 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Abhydro_lipase PF04083.16 EGO52423.1 - 4.6e-20 71.0 0.0 1e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EGO52423.1 - 3.3e-07 30.2 0.1 8.4e-07 28.9 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO52423.1 - 0.0045 16.3 0.0 0.0089 15.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF3899 PF13038.6 EGO52423.1 - 0.38 11.3 0.1 0.38 11.3 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) AAA PF00004.29 EGO52424.1 - 6.1e-49 165.8 0.0 2.6e-43 147.6 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGO52424.1 - 7.2e-05 23.2 0.2 0.019 15.4 0.0 3.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGO52424.1 - 0.00025 20.8 0.0 0.00062 19.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 EGO52424.1 - 0.00045 20.0 2.9 0.11 12.3 0.0 3.3 3 0 0 3 3 3 1 AAA+ lid domain Parvo_NS1 PF01057.17 EGO52424.1 - 0.00079 18.6 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 EGO52424.1 - 0.0034 17.5 0.0 0.0087 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EGO52424.1 - 0.0063 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 EGO52424.1 - 0.0082 15.7 0.0 0.032 13.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGO52424.1 - 0.0091 16.3 0.0 0.035 14.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 EGO52424.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 EGO52424.1 - 0.014 15.8 0.0 0.039 14.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EGO52424.1 - 0.028 13.8 0.1 0.054 12.9 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGO52424.1 - 0.03 14.3 0.1 0.13 12.2 0.0 2.2 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 EGO52424.1 - 0.039 13.3 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 EGO52424.1 - 0.044 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EGO52424.1 - 0.056 12.9 0.1 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.6 EGO52424.1 - 0.081 13.5 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGO52424.1 - 0.093 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGO52424.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EGO52424.1 - 0.14 11.9 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 EGO52424.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 EGO52424.1 - 0.17 11.9 0.1 0.72 9.9 0.0 2.1 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain SH3BGR PF04908.15 EGO52425.1 - 3.4e-05 23.9 0.2 0.00027 21.0 0.0 2.3 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein DUF4551 PF15087.6 EGO52425.1 - 1.8 7.3 11.9 2.3 7.0 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) BSP_II PF05432.11 EGO52425.1 - 2.4 7.8 20.2 4.6 6.8 20.2 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) KAR9 PF08580.10 EGO52425.1 - 8.4 4.8 20.7 10 4.5 20.7 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 PAT1 PF09770.9 EGO52425.1 - 8.6 4.5 17.4 10 4.3 17.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dynamitin PF04912.14 EGO52426.1 - 2.2e-97 326.8 10.1 3.4e-97 326.2 10.1 1.2 1 0 0 1 1 1 1 Dynamitin ThiS PF02597.20 EGO52426.1 - 5.9e-06 26.8 1.2 0.00011 22.8 0.0 3.7 4 1 0 4 4 2 1 ThiS family FlgN PF05130.12 EGO52426.1 - 0.0011 19.5 0.8 0.0011 19.5 0.8 2.8 3 0 0 3 3 2 1 FlgN protein Phage_GP20 PF06810.11 EGO52426.1 - 0.0024 17.7 15.2 0.14 11.9 4.4 3.4 3 0 0 3 3 3 2 Phage minor structural protein GP20 FH2 PF02181.23 EGO52426.1 - 0.011 14.8 3.8 0.076 12.1 0.0 2.8 3 0 0 3 3 3 0 Formin Homology 2 Domain Spore_III_AB PF09548.10 EGO52426.1 - 0.02 15.0 2.9 0.039 14.1 0.9 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) PCRF PF03462.18 EGO52426.1 - 0.039 13.8 11.9 0.028 14.3 2.3 3.0 2 1 1 3 3 3 0 PCRF domain FUSC PF04632.12 EGO52426.1 - 0.071 11.6 11.9 0.016 13.8 0.6 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Wtap PF17098.5 EGO52426.1 - 0.074 13.0 10.2 3.7 7.5 4.6 3.2 3 0 0 3 3 3 0 WTAP/Mum2p family YkyA PF10368.9 EGO52426.1 - 0.12 12.0 13.3 0.13 12.0 0.1 3.3 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein FapA PF03961.13 EGO52426.1 - 0.13 10.8 4.8 8.8 4.8 2.9 2.5 2 1 0 2 2 2 0 Flagellar Assembly Protein A DHR10 PF18595.1 EGO52426.1 - 0.15 12.1 19.5 6.3 6.9 0.0 3.9 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain V_ATPase_I PF01496.19 EGO52426.1 - 0.22 9.4 1.1 1.4 6.7 0.4 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Adaptin_binding PF10199.9 EGO52426.1 - 0.22 12.1 11.8 5.6 7.6 11.9 2.6 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 ATF7IP_BD PF16788.5 EGO52426.1 - 0.23 11.5 2.9 0.23 11.5 0.3 2.0 2 0 0 2 2 2 0 ATF-interacting protein binding domain Spectrin PF00435.21 EGO52426.1 - 0.24 11.9 9.9 0.67 10.5 2.9 3.3 3 0 0 3 3 3 0 Spectrin repeat DASH_Spc19 PF08287.11 EGO52426.1 - 0.26 11.2 16.3 0.066 13.1 2.2 2.7 2 2 0 2 2 2 0 Spc19 Dynactin_p22 PF07426.11 EGO52426.1 - 0.27 11.1 5.2 2.4 8.0 0.5 2.5 2 1 0 2 2 2 0 Dynactin subunit p22 Snapin_Pallidin PF14712.6 EGO52426.1 - 0.27 11.7 8.3 6.7 7.2 0.0 4.2 3 1 0 4 4 4 0 Snapin/Pallidin Matrilin_ccoil PF10393.9 EGO52426.1 - 0.28 11.1 2.7 11 6.0 0.2 2.9 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin ATP-synt_E PF05680.12 EGO52426.1 - 0.33 11.3 10.4 0.069 13.5 4.0 2.5 2 0 0 2 2 2 0 ATP synthase E chain DUF1192 PF06698.11 EGO52426.1 - 0.46 10.6 13.9 1.4 9.1 2.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF2203 PF09969.9 EGO52426.1 - 0.49 11.1 13.5 13 6.6 2.4 3.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Cwf_Cwc_15 PF04889.12 EGO52426.1 - 1.1 9.0 22.0 0.78 9.4 16.8 2.5 2 1 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ZapB PF06005.12 EGO52426.1 - 1.2 9.6 15.8 11 6.5 6.2 4.1 4 0 0 4 4 4 0 Cell division protein ZapB APG6_N PF17675.1 EGO52426.1 - 1.5 9.4 24.6 5.9 7.4 0.2 3.3 3 0 0 3 3 3 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 EGO52426.1 - 1.5 8.8 17.9 0.57 10.2 7.5 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MRPL52 PF18699.1 EGO52426.1 - 1.8 8.8 8.9 0.2 11.9 2.7 2.5 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Exonuc_VII_L PF02601.15 EGO52426.1 - 2.4 7.7 8.9 2.1e+02 1.3 8.8 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit GrpE PF01025.19 EGO52426.1 - 2.6 7.7 12.4 2.5 7.7 5.4 3.1 3 0 0 3 3 3 0 GrpE YlqD PF11068.8 EGO52426.1 - 3 8.2 5.8 48 4.3 0.0 3.0 3 0 0 3 3 3 0 YlqD protein DUF3053 PF11254.8 EGO52426.1 - 3.2 7.3 8.3 17 4.9 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3053) Baculo_PEP_C PF04513.12 EGO52426.1 - 3.3 7.7 5.2 2.3 8.2 0.7 2.6 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 EGO52426.1 - 5.2 7.4 14.1 3.1 8.1 4.9 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 EGO52426.1 - 6.3 5.6 17.1 0.94 8.3 4.4 3.1 2 1 0 2 2 2 0 Spc7 kinetochore protein Phage_Mu_Gam PF07352.12 EGO52426.1 - 6.6 6.6 15.5 0.26 11.2 6.2 2.7 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein LPP PF04728.13 EGO52426.1 - 6.8 7.2 11.1 41 4.7 0.7 4.3 3 1 0 3 3 3 0 Lipoprotein leucine-zipper CHD5 PF04420.14 EGO52426.1 - 8.4 6.2 8.7 2.5 7.9 2.9 2.4 2 0 0 2 2 2 0 CHD5-like protein RTC4 PF14474.6 EGO52427.1 - 2e-36 124.8 0.3 4.4e-36 123.7 0.3 1.6 1 0 0 1 1 1 1 RTC4-like domain zf-Di19 PF05605.12 EGO52427.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding PP2C PF00481.21 EGO52428.1 - 5.2e-63 213.1 0.0 1.1e-62 212.0 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EGO52428.1 - 1.5e-40 136.7 68.1 2.8e-09 36.6 0.5 10.8 5 3 7 12 12 12 10 Leucine rich repeat LRR_4 PF12799.7 EGO52428.1 - 1.9e-36 123.5 86.8 2.1e-05 24.8 5.7 13.3 8 3 8 16 16 16 13 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 EGO52428.1 - 2.4e-25 89.2 0.0 9.3e-25 87.3 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 EGO52428.1 - 4.5e-22 77.5 6.8 2.6e-21 75.1 1.8 3.2 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain LRR_9 PF14580.6 EGO52428.1 - 4.8e-06 26.2 29.1 0.011 15.3 3.0 5.0 2 1 2 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.6 EGO52428.1 - 0.0049 16.8 0.9 0.035 14.1 0.0 2.5 2 1 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EGO52428.1 - 0.011 16.1 72.3 13 6.8 0.0 18.6 16 3 2 18 18 18 0 Leucine Rich Repeat Yos1 PF08571.10 EGO52429.1 - 2.8e-33 114.0 0.8 3.1e-33 113.9 0.8 1.0 1 0 0 1 1 1 1 Yos1-like Rod_cone_degen PF15201.6 EGO52429.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Progressive rod-cone degeneration UCH PF00443.29 EGO52430.1 - 8.6e-50 169.6 0.0 1.9e-49 168.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO52430.1 - 7e-22 78.4 1.5 1.5e-20 74.0 0.2 2.7 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase TAF4 PF05236.14 EGO52430.1 - 9.4e-05 22.3 15.3 0.0002 21.2 15.3 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF5401 PF17380.2 EGO52430.1 - 0.1 10.7 12.5 0.18 9.8 12.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5401) VSG_B PF13206.6 EGO52430.1 - 0.24 10.6 13.4 0.37 10.0 13.4 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain Plasmodium_Vir PF05795.11 EGO52430.1 - 0.32 10.4 6.7 0.84 9.0 6.7 1.7 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4407 PF14362.6 EGO52430.1 - 0.51 9.6 6.6 0.84 8.9 6.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_C98 PF15499.6 EGO52430.1 - 9.6 5.6 12.5 0.1 12.1 0.5 2.7 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Sec61_beta PF03911.16 EGO52432.1 - 3.1e-19 68.7 1.9 4.1e-19 68.3 1.9 1.2 1 0 0 1 1 1 1 Sec61beta family DUF1180 PF06679.12 EGO52432.1 - 0.089 13.2 2.1 0.11 12.9 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NIF PF03031.18 EGO52433.1 - 3.9e-54 182.7 0.2 5.4e-54 182.2 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Mitofilin PF09731.9 EGO52433.1 - 3.8 6.3 13.1 5.3 5.8 13.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ABC_membrane_2 PF06472.15 EGO52435.1 - 1e-93 313.6 0.5 5e-93 311.4 0.0 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGO52435.1 - 5.3e-16 59.4 0.0 1.3e-15 58.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGO52435.1 - 0.006 17.0 0.3 0.018 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EGO52435.1 - 0.027 14.3 0.0 0.065 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Sigma54_activat PF00158.26 EGO52435.1 - 0.048 13.4 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 EGO52435.1 - 0.08 12.7 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 EGO52435.1 - 0.092 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EGO52435.1 - 0.096 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 EGO52435.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EGO52435.1 - 0.13 12.8 4.0 1.5 9.3 4.0 2.5 1 1 0 1 1 1 0 AAA domain Aldo_ket_red PF00248.21 EGO52437.1 - 6.3e-42 143.8 0.0 8.1e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.7 EGO52438.1 - 8.1e-35 118.3 25.5 3.4e-09 36.8 0.5 6.3 3 1 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGO52438.1 - 2e-23 81.9 24.9 8.2e-08 31.9 0.7 4.9 4 1 0 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 EGO52438.1 - 9.6e-16 57.8 9.8 3.1e-08 33.3 0.7 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EGO52438.1 - 9.8e-06 25.2 20.8 0.1 12.7 0.5 7.6 9 0 0 9 9 9 2 Leucine Rich repeat LRR_1 PF00560.33 EGO52438.1 - 0.00025 21.1 24.3 2.9 8.8 0.0 8.1 7 1 0 7 7 7 3 Leucine Rich Repeat Hydrolase_4 PF12146.8 EGO52439.1 - 0.0031 16.8 0.0 0.67 9.2 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGO52439.1 - 0.0057 16.1 0.0 0.0085 15.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2239 PF09998.9 EGO52440.1 - 0.38 10.5 1.8 0.33 10.7 0.5 1.6 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) BTB PF00651.31 EGO52441.1 - 1.7e-08 34.7 0.0 3.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 EGO52441.1 - 6.8e-06 26.2 0.0 0.00018 21.6 0.0 2.3 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain PCI PF01399.27 EGO52442.1 - 1.8e-10 41.3 0.0 1.9e-09 38.0 0.0 2.6 2 0 0 2 2 2 1 PCI domain DUF433 PF04255.14 EGO52442.1 - 0.1 12.5 0.4 0.53 10.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF433) PriCT_1 PF08708.11 EGO52442.1 - 0.12 12.1 0.8 1.3 8.8 0.0 2.7 3 0 0 3 3 3 0 Primase C terminal 1 (PriCT-1) Ribosomal_L18A PF01775.17 EGO52443.1 - 4.1e-55 185.1 0.2 5.3e-55 184.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Acetyltransf_3 PF13302.7 EGO52444.1 - 5.6e-33 114.5 0.0 8.4e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Propep_M14 PF02244.16 EGO52444.1 - 0.047 14.1 0.0 0.091 13.2 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase activation peptide AAA_lid_3 PF17862.1 EGO52447.1 - 0.042 13.7 0.1 0.083 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA+ lid domain DUF1656 PF07869.12 EGO52447.1 - 0.051 13.6 2.4 0.095 12.7 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) ATP-synt_E PF05680.12 EGO52448.1 - 1.3e-30 105.6 0.8 1.4e-30 105.5 0.8 1.0 1 0 0 1 1 1 1 ATP synthase E chain BPL_N PF09825.9 EGO52448.1 - 0.051 12.7 0.1 0.051 12.6 0.1 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal WD40 PF00400.32 EGO52449.1 - 2.6e-08 34.4 7.9 0.15 13.0 0.1 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat MtaB PF12176.8 EGO52449.1 - 0.057 12.2 0.2 0.089 11.6 0.2 1.2 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit Aldo_ket_red PF00248.21 EGO52450.1 - 6.4e-63 212.7 0.0 7.2e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TFIIA PF03153.13 EGO52451.1 - 2 8.3 14.2 0.088 12.8 2.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EGO52451.1 - 3.1 7.3 11.9 0.26 10.9 6.8 1.7 2 0 0 2 2 2 0 Spt20 family Torus PF16131.5 EGO52451.1 - 4 8.2 7.0 0.62 10.8 0.4 2.6 3 0 0 3 3 3 0 Torus domain CAP_GLY PF01302.25 EGO52452.1 - 4.9e-17 61.7 0.0 9.5e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 EGO52452.1 - 5.9e-12 45.6 9.6 0.0013 19.1 0.0 5.5 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGO52452.1 - 1e-09 38.0 7.3 0.013 15.3 1.7 5.3 5 1 0 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 EGO52452.1 - 1.1e-06 28.2 5.9 3.4 8.0 0.0 6.1 7 0 0 7 7 7 2 Leucine Rich repeat LRR_9 PF14580.6 EGO52452.1 - 8.5e-05 22.1 0.7 0.22 11.0 0.0 3.6 2 1 2 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.33 EGO52452.1 - 1.1 10.1 7.0 1.9e+02 3.3 0.0 5.5 6 1 0 6 6 6 0 Leucine Rich Repeat MaoC_dehydratas PF01575.19 EGO52453.1 - 5.2e-22 77.7 0.0 9e-22 76.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EGO52453.1 - 4.7e-07 30.0 0.0 0.00034 20.8 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase PI-PLC-X PF00388.19 EGO52456.1 - 5.1e-07 29.4 0.0 7.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain GPI-anchored PF10342.9 EGO52458.1 - 1.3e-21 77.2 1.2 3e-21 76.0 0.0 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Inhibitor_I48 PF10467.9 EGO52458.1 - 0.15 12.0 1.4 0.27 11.1 0.1 2.0 1 1 0 2 2 2 0 Peptidase inhibitor clitocypin Glycoprotein PF03409.15 EGO52458.1 - 2.8 6.7 8.1 0.25 10.1 1.9 1.9 2 0 0 2 2 2 0 Transmembrane glycoprotein Tubulin PF00091.25 EGO52459.1 - 1.3e-65 221.3 0.0 1.8e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGO52459.1 - 7.7e-43 145.7 0.0 1.2e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGO52459.1 - 0.0018 18.0 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.22 EGO52460.1 - 2e-12 46.8 0.1 1.8e-08 34.1 0.0 3.1 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 EGO52460.1 - 0.62 8.3 17.2 1.1 7.5 17.2 1.5 1 0 0 1 1 1 0 CDC45-like protein Sds3 PF08598.11 EGO52461.1 - 6.9e-15 55.6 10.5 6.9e-15 55.6 10.5 2.7 2 1 0 3 3 3 1 Sds3-like Coiled-coil_56 PF09813.9 EGO52462.1 - 0.00041 20.3 0.0 0.00046 20.2 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.8 EGO52463.1 - 5.4e-60 202.8 0.1 1.1e-59 201.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) GPW_gp25 PF04965.14 EGO52464.1 - 0.021 14.6 0.7 1.4 8.8 1.1 2.6 2 0 0 2 2 2 0 Gene 25-like lysozyme PspB PF06667.12 EGO52464.1 - 0.53 10.4 4.3 1.3 9.1 1.1 2.9 1 1 1 2 2 2 0 Phage shock protein B ABC_membrane PF00664.23 EGO52466.1 - 5.2e-05 23.0 2.2 0.018 14.7 0.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region HET-s_218-289 PF11558.8 EGO52466.1 - 0.12 12.5 0.8 0.29 11.2 0.2 1.8 2 0 0 2 2 2 0 Het-s 218-289 UVR PF02151.19 EGO52468.1 - 0.14 11.9 0.6 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 UvrB/uvrC motif Pkinase PF00069.25 EGO52469.1 - 4.1e-69 232.9 0.0 5.6e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO52469.1 - 5e-34 117.7 0.0 8.1e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO52469.1 - 3.2e-05 23.4 0.0 4.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGO52469.1 - 0.0022 17.4 0.0 0.0048 16.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EGO52469.1 - 0.0028 17.2 0.2 0.022 14.3 0.1 2.4 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL UQ_con PF00179.26 EGO52470.1 - 1.2e-25 89.8 0.0 1.4e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO52470.1 - 5.8e-06 26.0 0.0 6.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGO52470.1 - 0.0031 17.4 0.0 0.0046 16.8 0.0 1.2 1 0 0 1 1 1 1 UEV domain Sec1 PF00995.23 EGO52471.1 - 5.6e-123 412.2 0.0 6.3e-123 412.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Amino_oxidase PF01593.24 EGO52472.1 - 7.5e-82 276.0 0.0 1e-80 272.3 0.0 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 EGO52472.1 - 1.6e-14 54.0 0.1 6.2e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain HMG_box PF00505.19 EGO52472.1 - 2.4e-06 27.8 3.2 2.4e-06 27.8 3.2 2.8 1 1 1 2 2 2 1 HMG (high mobility group) box NAD_binding_8 PF13450.6 EGO52472.1 - 4e-06 27.0 0.0 9.8e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.10 EGO52472.1 - 5.1e-06 27.0 2.5 5.1e-06 27.0 2.5 2.3 1 1 1 2 2 2 1 HMG-box domain Pyr_redox_2 PF07992.14 EGO52472.1 - 0.038 13.2 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO52472.1 - 0.049 13.2 1.4 0.083 12.5 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase ATP-synt PF00231.19 EGO52473.1 - 1.5e-80 271.0 2.0 1.8e-80 270.7 2.0 1.0 1 0 0 1 1 1 1 ATP synthase DUF5471 PF17565.2 EGO52473.1 - 0.1 12.9 0.9 0.29 11.5 0.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5471) Topoisom_I PF01028.20 EGO52474.1 - 5e-96 320.4 9.5 1e-95 319.4 9.5 1.6 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EGO52474.1 - 3.6e-90 301.2 2.9 3.6e-90 301.2 2.9 2.8 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EGO52474.1 - 6.7e-31 106.0 0.1 3.6e-30 103.7 0.1 2.4 1 0 0 1 1 1 1 C-terminal topoisomerase domain Glyco_hydro_16 PF00722.21 EGO52475.1 - 4.7e-43 146.7 0.7 4.7e-43 146.7 0.7 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 p450 PF00067.22 EGO52476.1 - 1.9e-63 214.8 0.0 2.7e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_20 PF00728.22 EGO52477.1 - 7.6e-84 282.1 0.0 9.6e-84 281.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGO52477.1 - 9.4e-32 110.5 0.1 2.7e-31 109.0 0.0 1.8 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EGO52477.1 - 8.2e-07 29.8 0.2 0.00058 20.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, domain 2 ATXN-1_C PF12547.8 EGO52477.1 - 0.087 13.2 1.5 0.32 11.4 1.5 1.9 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator Amino_oxidase PF01593.24 EGO52478.1 - 7.7e-15 55.1 0.0 1.2e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGO52478.1 - 2.1e-09 37.5 0.0 6e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain zf-CCCH_2 PF14608.6 EGO52478.1 - 2.4e-07 31.0 69.1 5.1e-05 23.6 14.3 5.7 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger DAO PF01266.24 EGO52478.1 - 1.1e-06 28.5 0.1 0.013 15.1 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO52478.1 - 0.0032 16.7 0.0 0.18 11.0 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 EGO52478.1 - 0.012 14.5 0.0 0.28 9.9 0.0 2.1 2 0 0 2 2 2 0 MCRA family Nab2 PF11517.8 EGO52478.1 - 0.073 13.4 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Pyr_redox PF00070.27 EGO52478.1 - 0.13 12.8 0.0 11 6.6 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Med14 PF08638.11 EGO52479.1 - 9.4e-49 165.4 0.1 1e-32 113.2 0.0 3.3 2 1 1 3 3 3 2 Mediator complex subunit MED14 G6PD_C PF02781.16 EGO52480.1 - 1.5e-115 385.4 0.0 2.5e-115 384.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EGO52480.1 - 1.3e-61 208.3 0.0 2.4e-61 207.5 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.8 EGO52480.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) Ribosomal_L35Ae PF01247.18 EGO52481.1 - 3.1e-41 139.5 0.2 3.5e-41 139.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EGO52481.1 - 0.00015 21.9 0.0 0.18 12.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2406 PF10295.9 EGO52482.1 - 4.4e-06 27.3 0.1 1.6e-05 25.5 0.1 2.1 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) VMA21 PF09446.10 EGO52483.1 - 3.3e-15 55.9 8.7 4.7e-15 55.4 8.7 1.2 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.23 EGO52484.1 - 9.5e-54 182.4 0.0 1.6e-53 181.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO52484.1 - 5.7e-17 62.1 0.1 1.7e-16 60.5 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGO52484.1 - 0.00015 21.1 0.5 0.00046 19.5 0.1 2.0 2 1 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase HIGH_NTase1_ass PF16581.5 EGO52484.1 - 0.039 13.9 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region DUF3336 PF11815.8 EGO52485.1 - 1.4e-33 115.5 0.0 4.1e-32 110.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EGO52485.1 - 1e-12 48.7 0.3 2.6e-12 47.4 0.3 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Sm_multidrug_ex PF06695.11 EGO52485.1 - 0.14 12.8 0.8 0.36 11.5 0.2 1.9 2 0 0 2 2 2 0 Putative small multi-drug export protein Adeno_GP19K PF04881.13 EGO52486.1 - 0.13 12.2 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Adenovirus GP19K Lipase_GDSL_2 PF13472.6 EGO52488.1 - 5.2e-22 79.1 0.8 8.1e-22 78.5 0.8 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGO52488.1 - 3e-08 33.9 0.0 7.8e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase BOP1NT PF08145.12 EGO52489.1 - 2.9e-104 348.6 6.5 4.1e-104 348.1 6.5 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EGO52489.1 - 2.2e-20 72.6 2.3 2e-07 31.6 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO52489.1 - 7.6e-07 29.3 0.0 0.0015 18.8 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO52489.1 - 0.038 12.7 0.0 0.059 12.0 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Frtz PF11768.8 EGO52489.1 - 0.26 9.5 0.0 0.7 8.1 0.0 1.6 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Zn_clus PF00172.18 EGO52490.1 - 8.9e-06 25.7 10.1 1.7e-05 24.8 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SURF4 PF02077.15 EGO52491.1 - 1.1e-96 323.5 7.9 1.3e-96 323.3 7.9 1.0 1 0 0 1 1 1 1 SURF4 family Halogen_Hydrol PF10112.9 EGO52491.1 - 2.7 8.0 4.4 8.4 6.4 1.3 2.3 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein VSP PF03302.13 EGO52492.1 - 0.00045 19.2 1.1 0.00073 18.5 1.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Alg6_Alg8 PF03155.15 EGO52493.1 - 1.8e-129 432.9 27.8 1.8e-83 281.1 10.4 2.2 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Leo1 PF04004.13 EGO52495.1 - 2.6e-34 118.5 0.1 5.8e-34 117.3 0.1 1.6 1 0 0 1 1 1 1 Leo1-like protein DUF4407 PF14362.6 EGO52495.1 - 5.8 6.2 8.3 0.25 10.7 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mob1_phocein PF03637.17 EGO52496.1 - 7.5e-42 143.2 0.0 1.1e-41 142.6 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family CorA PF01544.18 EGO52497.1 - 3.4e-40 138.2 0.3 2e-39 135.6 0.3 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CSTF2_hinge PF14327.6 EGO52498.1 - 2.7e-33 114.2 2.5 5.2e-33 113.3 2.5 1.5 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EGO52498.1 - 1.6e-22 79.1 0.0 2.8e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EGO52498.1 - 3.1e-07 29.9 4.4 3.1e-07 29.9 4.4 3.1 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 EGO52498.1 - 0.054 13.6 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Spo7_2_N PF15407.6 EGO52498.1 - 0.21 11.3 0.0 0.47 10.1 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 Band_7 PF01145.25 EGO52499.1 - 1.2e-24 87.3 2.2 1.8e-24 86.7 2.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.19 EGO52499.1 - 0.013 15.1 1.1 0.018 14.5 1.1 1.2 1 0 0 1 1 1 0 MraW methylase family RepB-RCR_reg PF10723.9 EGO52499.1 - 0.078 12.9 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Replication regulatory protein RepB DivIVA PF05103.13 EGO52499.1 - 5.9 7.0 11.1 13 5.9 11.1 1.6 1 1 0 1 1 1 0 DivIVA protein ubiquitin PF00240.23 EGO52500.1 - 2e-26 91.5 0.2 2.2e-26 91.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGO52500.1 - 1.2e-16 60.3 0.3 1.3e-16 60.2 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGO52500.1 - 0.00019 21.8 0.1 0.00062 20.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGO52500.1 - 0.0031 17.4 0.0 0.0039 17.1 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGO52500.1 - 0.072 13.2 0.1 0.22 11.6 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EGO52500.1 - 0.17 12.0 0.4 2.7 8.1 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain Elongin_A PF06881.11 EGO52501.1 - 2.2e-22 79.6 0.9 4.3e-22 78.6 0.9 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Slu7 PF11708.8 EGO52501.1 - 9.4 5.9 9.7 63 3.2 9.7 2.0 1 1 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor THOC7 PF05615.13 EGO52502.1 - 8.7e-47 158.7 6.6 8.7e-47 158.7 6.6 2.0 2 0 0 2 2 2 1 Tho complex subunit 7 Med9 PF07544.13 EGO52502.1 - 0.024 14.7 1.5 0.092 12.9 1.5 1.9 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Colicin-DNase PF12639.7 EGO52502.1 - 0.29 12.0 2.2 0.3 11.9 0.6 1.9 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin Rotamase_2 PF13145.6 EGO52502.1 - 0.64 10.9 7.0 0.85 10.5 3.0 2.3 2 0 0 2 2 2 0 PPIC-type PPIASE domain E1-E2_ATPase PF00122.20 EGO52503.1 - 5e-50 169.5 4.9 9.1e-50 168.7 2.4 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGO52503.1 - 3e-46 157.4 5.5 5.9e-46 156.5 5.5 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGO52503.1 - 7e-24 85.3 2.5 6.1e-23 82.2 2.5 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGO52503.1 - 3.8e-20 71.3 0.1 1e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGO52503.1 - 8e-20 70.7 0.0 1.5e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGO52503.1 - 8.9e-09 35.4 0.8 5.6e-06 26.3 0.9 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGO52503.1 - 7e-06 26.6 0.0 3e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TUG-UBL1 PF11470.8 EGO52504.1 - 5.4e-27 93.8 0.1 9.2e-26 89.9 0.1 2.5 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 EGO52504.1 - 0.00077 19.6 0.0 0.0061 16.7 0.0 2.4 3 0 0 3 3 3 1 UBX domain RBD PF02196.15 EGO52504.1 - 0.1 12.7 0.1 0.58 10.3 0.0 2.3 3 0 0 3 3 3 0 Raf-like Ras-binding domain Ribosomal_L36e PF01158.18 EGO52505.1 - 9e-42 141.3 6.8 1e-41 141.1 6.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.9 EGO52505.1 - 0.076 13.1 1.7 0.09 12.9 1.7 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Lipase_3 PF01764.25 EGO52508.1 - 1.7e-29 102.5 0.0 2.5e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EGO52508.1 - 2.9e-05 24.8 3.6 4.7e-05 24.1 3.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO52508.1 - 3.2e-05 23.3 0.0 4.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EGO52508.1 - 0.0033 17.6 0.0 0.0051 17.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 EGO52508.1 - 0.0053 16.4 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 EGO52508.1 - 0.0069 16.0 0.1 0.11 12.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Esterase PF00756.20 EGO52508.1 - 0.0071 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 EGO52508.1 - 0.08 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein 14-3-3 PF00244.20 EGO52509.1 - 7.4e-108 359.2 1.9 1.1e-107 358.6 1.9 1.3 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 EGO52509.1 - 0.012 14.0 0.9 0.02 13.3 0.9 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 ARL2_Bind_BART PF11527.8 EGO52509.1 - 0.039 14.1 0.4 1.9 8.6 0.3 2.4 1 1 1 2 2 2 0 The ARF-like 2 binding protein BART Ribosomal_60s PF00428.19 EGO52509.1 - 2.7 8.6 14.9 0.24 12.0 6.1 2.6 2 1 0 2 2 2 0 60s Acidic ribosomal protein Syja_N PF02383.18 EGO52512.1 - 6.7e-66 222.8 0.0 1.8e-65 221.3 0.0 1.7 2 0 0 2 2 2 1 SacI homology domain TPR_14 PF13428.6 EGO52513.1 - 7e-08 32.7 6.9 0.026 15.3 0.0 6.2 4 3 3 7 7 7 2 Tetratricopeptide repeat Suf PF05843.14 EGO52513.1 - 1.2e-05 25.5 2.8 0.0078 16.2 0.0 3.2 2 1 0 3 3 3 2 Suppressor of forked protein (Suf) DUF3022 PF11226.8 EGO52513.1 - 0.24 11.9 1.4 27 5.3 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3022) peroxidase PF00141.23 EGO52514.1 - 6e-48 163.5 0.0 9.1e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase ATP11 PF06644.11 EGO52515.1 - 6.4e-102 341.0 0.0 7.4e-102 340.8 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Glyphos_transf PF04464.14 EGO52515.1 - 0.033 13.2 0.1 0.047 12.7 0.1 1.2 1 0 0 1 1 1 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Pol_alpha_B_N PF08418.10 EGO52515.1 - 0.087 12.8 0.6 0.14 12.1 0.6 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SpoOE-like PF09388.10 EGO52515.1 - 0.39 10.7 1.2 13 5.8 0.1 2.3 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein AMP-binding PF00501.28 EGO52516.1 - 9.1e-91 304.5 0.0 1.1e-90 304.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO52516.1 - 5.1e-15 56.2 0.3 1.2e-14 55.0 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain COG4 PF08318.12 EGO52519.1 - 6.3e-96 321.4 0.0 5.9e-75 252.4 0.0 2.3 1 1 1 2 2 2 2 COG4 transport protein CLZ PF16526.5 EGO52519.1 - 2.1 8.8 5.4 1.1 9.7 0.2 3.1 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels E1-E2_ATPase PF00122.20 EGO52520.1 - 1.3e-47 161.7 1.0 3.7e-47 160.2 1.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGO52520.1 - 6.1e-45 153.2 1.5 6.1e-45 153.2 1.5 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EGO52520.1 - 2e-19 69.0 0.0 4e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 EGO52520.1 - 1.7e-17 64.4 8.0 3.4e-16 60.2 6.1 3.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGO52520.1 - 1.2e-11 44.5 0.0 2.3e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGO52520.1 - 1.4e-05 25.0 0.7 3e-05 23.9 0.7 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.13 EGO52521.1 - 1.2e-33 115.5 0.0 2.4e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EGO52521.1 - 3.4e-09 35.9 0.2 2.4e-08 33.1 0.1 2.4 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein Peptidase_S9 PF00326.21 EGO52522.1 - 8.7e-54 182.2 0.0 1.5e-53 181.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 EGO52522.1 - 9.9e-05 21.4 0.0 0.00015 20.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 EGO52522.1 - 0.00011 21.0 0.0 0.012 14.3 0.0 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) PD40 PF07676.12 EGO52522.1 - 0.019 14.9 0.0 14 5.8 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat NuA4 PF09340.10 EGO52524.1 - 1.1e-26 92.5 0.6 1.1e-26 92.5 0.6 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF4551 PF15087.6 EGO52524.1 - 0.23 10.3 5.6 0.28 10.0 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ABATE PF07336.11 EGO52525.1 - 0.083 13.6 3.9 0.12 13.0 0.9 2.5 1 1 0 2 2 2 0 Putative stress-induced transcription regulator Pheromone PF08015.11 EGO52527.1 - 0.00069 20.6 3.9 0.0093 17.0 0.8 2.9 2 0 0 2 2 2 1 Fungal mating-type pheromone DUF3482 PF11981.8 EGO52527.1 - 4.9 6.5 12.6 12 5.2 6.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) PWI PF01480.17 EGO52529.1 - 2.2e-30 104.8 0.2 3.8e-30 104.0 0.2 1.4 1 0 0 1 1 1 1 PWI domain GYD PF08734.11 EGO52529.1 - 0.064 13.2 0.5 6 6.9 0.4 2.5 2 0 0 2 2 2 0 GYD domain YfhD PF14151.6 EGO52530.1 - 0.22 11.7 3.6 5.4 7.3 0.4 3.1 3 0 0 3 3 3 0 YfhD-like protein FAA_hydrolase PF01557.18 EGO52531.1 - 1.8e-51 174.9 0.0 2.2e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Ctr PF04145.15 EGO52532.1 - 2.4e-33 115.9 0.7 2.9e-33 115.6 0.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family PHO4 PF01384.20 EGO52532.1 - 1 8.4 4.6 2.3 7.2 4.6 1.6 1 1 0 1 1 1 0 Phosphate transporter family NUDIX PF00293.28 EGO52533.1 - 2.6e-09 37.2 0.0 2.5e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 NUDIX domain EXS PF03124.14 EGO52535.1 - 2.1e-110 369.2 9.4 2.4e-110 369.0 9.4 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.14 EGO52537.1 - 3.9e-49 167.3 0.2 4.9e-49 166.9 0.2 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 EGO52537.1 - 4.6e-12 45.6 8.6 7.4e-12 44.9 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO52537.1 - 1.5e-11 44.5 8.7 2.5e-11 43.7 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGO52537.1 - 1.8e-10 40.5 6.6 2.7e-10 39.9 6.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO52537.1 - 5.6e-10 38.9 6.4 9.5e-10 38.2 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO52537.1 - 6.6e-08 32.5 6.3 1.4e-07 31.4 6.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGO52537.1 - 4.5e-07 29.7 5.2 7.5e-07 29.0 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGO52537.1 - 6e-07 29.2 7.0 1e-06 28.5 7.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGO52537.1 - 6.6e-07 29.4 7.7 1.1e-06 28.7 7.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EGO52537.1 - 9.3e-07 29.0 7.2 1.7e-06 28.2 7.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 EGO52537.1 - 0.00018 21.6 5.1 0.00031 20.8 5.1 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 EGO52537.1 - 0.0045 16.8 2.2 0.0084 16.0 2.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 EGO52537.1 - 0.0077 16.0 0.7 0.015 15.1 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 EGO52537.1 - 0.04 14.0 2.9 0.093 12.8 2.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGO52537.1 - 0.16 11.8 8.0 0.47 10.3 7.9 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EGO52537.1 - 0.58 9.9 3.6 1.3 8.8 3.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGO52537.1 - 0.62 9.7 5.2 1.1 8.9 5.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 EGO52537.1 - 3.9 7.6 5.7 7.7 6.6 5.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon Hydrolase_4 PF12146.8 EGO52538.1 - 6.4e-17 61.6 0.1 2.5e-12 46.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO52538.1 - 1.2e-12 48.1 0.3 3.2e-08 33.6 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO52538.1 - 1.2e-05 26.0 0.0 3.1e-05 24.7 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF818 PF05677.12 EGO52538.1 - 7.1e-05 21.9 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) AXE1 PF05448.12 EGO52538.1 - 9.4e-05 21.2 0.1 2.4 6.7 0.0 3.0 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 EGO52538.1 - 0.0016 18.1 0.0 0.0047 16.6 0.0 1.8 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DUF1057 PF06342.12 EGO52538.1 - 0.0023 17.0 0.1 0.003 16.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S9 PF00326.21 EGO52538.1 - 0.012 15.1 0.1 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.18 EGO52538.1 - 0.041 13.4 0.0 6.7 6.2 0.0 2.5 3 0 0 3 3 3 0 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EGO52538.1 - 0.12 11.9 0.0 0.55 9.8 0.0 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 EGO52538.1 - 0.13 12.0 0.0 0.42 10.4 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 EGO52538.1 - 0.18 11.4 0.0 0.42 10.2 0.0 1.5 2 0 0 2 2 2 0 Putative esterase Peptidase_S28 PF05577.12 EGO52538.1 - 0.28 9.9 0.0 0.52 9.0 0.0 1.4 1 0 0 1 1 1 0 Serine carboxypeptidase S28 zf-LYAR PF08790.11 EGO52540.1 - 2e-14 53.2 4.6 2e-14 53.2 4.6 1.9 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger R3H PF01424.22 EGO52541.1 - 2.9e-16 59.2 0.1 6.5e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 R3H domain Tantalus PF15386.6 EGO52542.1 - 0.54 10.4 2.1 2.5 8.3 0.1 2.7 3 0 0 3 3 3 0 Drosophila Tantalus-like PTPA PF03095.15 EGO52543.1 - 7.5e-112 373.7 0.0 8.9e-112 373.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RNase_PH PF01138.21 EGO52544.1 - 9.1e-14 52.1 0.1 1.7e-13 51.2 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_kinase PF01513.21 EGO52546.1 - 3.8e-80 269.2 0.0 5.5e-80 268.7 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Homeodomain PF00046.29 EGO52547.1 - 3.7e-15 55.5 2.1 8.8e-15 54.3 2.1 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGO52547.1 - 0.11 12.4 0.6 0.29 11.1 0.6 1.7 1 0 0 1 1 1 0 Homeobox KN domain zf-GRF PF06839.12 EGO52548.1 - 7.6e-13 48.3 0.8 2.1e-12 46.9 0.8 1.8 1 0 0 1 1 1 1 GRF zinc finger Phage_int_SAM_1 PF02899.17 EGO52548.1 - 0.17 12.2 0.2 0.49 10.7 0.2 1.8 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain QWRF PF04484.12 EGO52548.1 - 8.4 6.0 10.9 15 5.2 10.9 1.4 1 0 0 1 1 1 0 QWRF family ELMO_CED12 PF04727.13 EGO52549.1 - 8.2e-51 172.6 0.0 2.1e-50 171.3 0.0 1.7 2 0 0 2 2 2 1 ELMO/CED-12 family PH_12 PF16457.5 EGO52549.1 - 1.2e-37 129.4 0.2 2.3e-37 128.5 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 EGO52549.1 - 2.9e-13 50.1 0.0 8.3e-13 48.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) C2 PF00168.30 EGO52550.1 - 8.1e-86 283.0 0.1 9.2e-24 83.7 0.0 5.5 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 EGO52550.1 - 0.0015 18.0 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain NT-C2 PF10358.9 EGO52550.1 - 0.0027 17.4 0.7 0.019 14.7 0.0 2.5 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins FKBP_C PF00254.28 EGO52550.1 - 0.016 15.5 0.1 0.07 13.5 0.0 2.2 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase zf-CCCH PF00642.24 EGO52551.1 - 2.8e-08 33.5 20.0 2.9e-07 30.2 2.5 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGO52551.1 - 0.0057 16.7 3.3 0.0057 16.7 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain RRM_1 PF00076.22 EGO52551.1 - 0.014 15.2 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 EGO52551.1 - 0.015 16.0 3.4 0.48 11.1 0.2 2.4 2 0 0 2 2 2 0 Torus domain SCRG1 PF15224.6 EGO52551.1 - 0.086 13.0 0.1 0.086 13.0 0.1 2.3 2 0 0 2 2 2 0 Scrapie-responsive protein 1 zf-CCCH_3 PF15663.5 EGO52551.1 - 0.29 11.4 5.0 0.3 11.3 1.2 2.4 2 0 0 2 2 2 0 Zinc-finger containing family Oxysterol_BP PF01237.18 EGO52553.1 - 7.6e-88 294.8 0.0 6.9e-79 265.4 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Ammonium_transp PF00909.21 EGO52554.1 - 8.1e-115 383.7 28.6 9.3e-115 383.5 28.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family His_Phos_2 PF00328.22 EGO52555.1 - 2.9e-54 184.9 0.0 3.4e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CRT10 PF08728.10 EGO52556.1 - 2.4e-20 72.4 0.0 1e-12 47.1 0.0 2.1 2 0 0 2 2 2 2 CRT10 Cellulase PF00150.18 EGO52557.1 - 1.4e-39 136.3 0.0 1.6e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) 7tm_2 PF00002.24 EGO52558.1 - 1.5e-07 30.9 11.8 2.5e-07 30.2 11.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 EGO52558.1 - 0.071 12.2 8.3 0.015 14.4 3.6 1.9 1 1 0 2 2 2 0 Slime mold cyclic AMP receptor Pkinase_Tyr PF07714.17 EGO52560.1 - 4.9e-06 26.0 0.0 4.7e-05 22.8 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 EGO52560.1 - 8.5e-06 25.3 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF4145 PF13643.6 EGO52561.1 - 0.081 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) Zn_clus PF00172.18 EGO52563.1 - 0.0018 18.4 5.2 0.0036 17.4 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 EGO52564.1 - 4.9e-29 102.0 0.2 6.2e-29 101.6 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EGO52564.1 - 0.0096 15.1 0.1 0.015 14.4 0.1 1.2 1 0 0 1 1 1 1 CsiD DSPn PF14671.6 EGO52565.1 - 2.1e-41 141.7 0.0 7.2e-39 133.4 0.0 2.7 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EGO52565.1 - 3.3e-17 62.6 0.0 6.5e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGO52565.1 - 7.2e-06 25.7 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGO52565.1 - 0.0018 18.4 0.0 0.0095 16.1 0.0 2.0 2 0 0 2 2 2 1 Inositol hexakisphosphate CDKN3 PF05706.12 EGO52565.1 - 0.23 11.1 0.1 0.43 10.2 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Pcc1 PF09341.10 EGO52567.1 - 1.4e-30 105.2 0.7 1.7e-30 104.9 0.7 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 WD40 PF00400.32 EGO52568.1 - 3.9e-53 176.3 18.3 3.8e-10 40.2 0.2 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO52568.1 - 1e-22 80.2 0.0 0.00092 19.5 0.0 6.2 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO52568.1 - 6.8e-09 35.1 0.3 0.0053 15.8 0.0 4.9 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGO52568.1 - 1.8e-07 31.3 0.1 0.0013 18.7 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGO52568.1 - 0.00042 19.1 16.7 0.097 11.3 0.1 5.4 4 2 2 6 6 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGO52568.1 - 0.00054 18.8 1.8 0.42 9.3 0.1 3.4 2 1 0 3 3 3 2 Nup133 N terminal like Frtz PF11768.8 EGO52568.1 - 0.0046 15.3 0.0 0.11 10.8 0.0 2.2 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz BBS2_Mid PF14783.6 EGO52568.1 - 0.006 16.6 0.0 0.77 9.8 0.0 3.1 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EGO52568.1 - 0.007 15.7 0.0 0.083 12.2 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain VID27 PF08553.10 EGO52568.1 - 0.009 15.1 0.0 5.7 5.9 0.0 3.8 4 1 1 5 5 5 1 VID27 C-terminal WD40-like domain PD40 PF07676.12 EGO52568.1 - 0.011 15.7 0.0 1.4 9.0 0.1 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PALB2_WD40 PF16756.5 EGO52568.1 - 0.099 11.5 1.6 7.8 5.3 0.1 3.3 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Apt1 PF10351.9 EGO52568.1 - 1.9 7.2 17.9 2.6 6.8 17.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EGO52568.1 - 5.6 5.4 12.0 7.9 4.9 12.0 1.1 1 0 0 1 1 1 0 Macoilin family Exo_endo_phos PF03372.23 EGO52569.1 - 6.2e-10 39.0 0.0 1.4e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 EGO52570.1 - 2.6e-21 76.2 0.1 2.7e-15 56.5 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO52570.1 - 2e-06 27.3 0.1 2.3e-05 23.8 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGO52570.1 - 0.0025 17.8 0.5 0.0044 17.0 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGO52570.1 - 0.091 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FKBP_C PF00254.28 EGO52571.1 - 3.3e-33 113.9 0.0 8.6e-32 109.3 0.0 2.6 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EGO52571.1 - 1.3e-31 109.3 0.9 1.3e-31 109.3 0.9 2.8 2 2 0 2 2 2 1 Nucleoplasmin-like domain Glyco_trans_2_3 PF13632.6 EGO52572.1 - 7.2e-20 71.7 0.3 1.2e-19 71.0 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_7N PF13733.6 EGO52572.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 FmiP_Thoc5 PF09766.9 EGO52574.1 - 5.5e-33 114.8 11.9 7e-33 114.4 11.9 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 EGO52574.1 - 0.033 14.2 8.5 0.061 13.4 4.9 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus TSC22 PF01166.18 EGO52574.1 - 0.046 14.0 5.3 0.098 13.0 0.1 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Microvir_H PF04687.12 EGO52574.1 - 0.22 10.9 0.1 0.22 10.9 0.1 1.5 2 0 0 2 2 2 0 Microvirus H protein (pilot protein) DUF3958 PF13125.6 EGO52574.1 - 0.22 11.8 12.3 0.82 9.9 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3958) Flagellin_N PF00669.20 EGO52574.1 - 0.34 11.0 3.4 1.3 9.1 0.8 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF4200 PF13863.6 EGO52574.1 - 0.37 11.2 14.5 1.7 9.1 1.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 EGO52574.1 - 0.74 9.8 11.6 0.67 10.0 3.4 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EGO52574.1 - 1.1 9.3 4.4 6.3 6.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 EGO52574.1 - 1.9 8.7 10.8 0.24 11.6 3.1 2.8 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Casc1_N PF15927.5 EGO52574.1 - 3.2 7.4 13.2 0.081 12.6 6.0 1.9 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Atg14 PF10186.9 EGO52574.1 - 3.6 6.6 9.4 3 6.8 5.4 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 EGO52574.1 - 4 7.5 14.7 3.4 7.7 4.0 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HlyIII PF03006.20 EGO52575.1 - 3.4e-62 210.1 21.8 4.2e-62 209.8 21.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related RabGAP-TBC PF00566.18 EGO52576.1 - 8.2e-33 113.9 1.2 1.1e-26 93.9 0.0 2.8 3 0 0 3 3 3 2 Rab-GTPase-TBC domain TFIIA PF03153.13 EGO52576.1 - 0.05 13.6 12.7 0.073 13.1 12.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sulfate_transp PF00916.20 EGO52577.1 - 5.1e-105 351.3 19.2 6.5e-105 351.0 19.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGO52577.1 - 4.1e-08 32.9 0.0 7.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.10 EGO52577.1 - 0.17 11.8 8.3 0.043 13.8 1.2 3.0 2 0 0 2 2 2 0 Stannin transmembrane zf-UBR PF02207.20 EGO52578.1 - 7.7e-19 67.6 16.8 1.9e-18 66.3 16.8 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EGO52578.1 - 0.00023 20.9 0.0 0.00059 19.6 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS UCR_UQCRX_QCR9 PF05365.12 EGO52579.1 - 1.9e-28 98.2 1.8 2e-28 98.1 1.8 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.10 EGO52580.1 - 4e-15 55.4 3.8 7.5e-15 54.5 3.8 1.5 1 0 0 1 1 1 1 Mago binding RR_TM4-6 PF06459.12 EGO52580.1 - 3.5 7.4 10.4 4.4 7.1 10.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BCS1_N PF08740.11 EGO52581.1 - 1.8e-42 145.5 0.0 2.5e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EGO52581.1 - 3.7e-20 72.7 0.0 5.8e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGO52581.1 - 0.00021 21.1 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGO52581.1 - 0.00024 21.1 0.0 0.0006 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO52581.1 - 0.00038 20.9 0.0 0.0011 19.4 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EGO52581.1 - 0.00055 19.5 0.0 0.00093 18.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 EGO52581.1 - 0.0023 17.1 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EGO52581.1 - 0.0062 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO52581.1 - 0.0075 16.8 0.0 0.015 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGO52581.1 - 0.0076 16.0 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGO52581.1 - 0.014 15.1 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGO52581.1 - 0.017 14.5 0.1 0.13 11.6 0.0 2.1 2 1 1 3 3 3 0 KaiC Rad17 PF03215.15 EGO52581.1 - 0.021 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 EGO52581.1 - 0.024 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGO52581.1 - 0.024 14.8 0.0 0.087 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGO52581.1 - 0.032 14.6 0.1 0.089 13.2 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ABC_tran PF00005.27 EGO52581.1 - 0.043 14.3 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 EGO52581.1 - 0.082 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EGO52581.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EGO52581.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 EGO52581.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 EGO52581.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_6 PF12774.7 EGO52581.1 - 0.23 10.4 0.0 0.34 9.8 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region PPV_E1_C PF00519.17 EGO52581.1 - 0.26 10.1 0.0 0.4 9.5 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Ribosomal_S11 PF00411.19 EGO52582.1 - 5.2e-10 39.7 0.0 8.3e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.15 EGO52583.1 - 7.7e-38 129.9 0.3 1.4e-37 129.0 0.0 1.6 2 0 0 2 2 2 1 Tim44-like domain DUF3347 PF11827.8 EGO52583.1 - 0.005 17.1 0.5 0.01 16.0 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3347) ABC_tran PF00005.27 EGO52584.1 - 2.4e-31 109.1 0.0 4.3e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EGO52584.1 - 1.7e-23 83.7 8.2 1.7e-23 83.7 8.2 1.9 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.19 EGO52584.1 - 1.3e-05 24.7 0.0 3.3e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 EGO52584.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_15 PF13175.6 EGO52584.1 - 0.027 14.2 0.0 0.069 12.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EGO52584.1 - 0.028 14.3 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 EGO52584.1 - 0.039 13.7 0.1 0.098 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGO52584.1 - 0.14 12.5 0.1 0.49 10.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGO52584.1 - 0.19 12.1 0.3 1.1 9.6 0.3 2.1 1 1 1 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 EGO52584.1 - 1.2 9.4 4.8 1.3 9.3 0.2 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RRM_1 PF00076.22 EGO52585.1 - 9.8e-14 50.9 0.0 1.5e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGO52585.1 - 0.036 14.1 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Cep57_MT_bd PF06657.13 EGO52586.1 - 7.3e-24 84.0 0.8 7.3e-24 84.0 0.8 8.1 7 3 2 9 9 9 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 EGO52586.1 - 4.2e-14 52.4 8.5 4.2e-14 52.4 8.5 8.9 6 2 3 9 9 9 1 Centrosome localisation domain of PPC89 SOGA PF11365.8 EGO52586.1 - 0.0075 17.4 1.7 0.0075 17.4 1.7 8.7 8 1 1 9 9 9 1 Protein SOGA ZapB PF06005.12 EGO52586.1 - 0.01 16.3 2.9 0.01 16.3 2.9 9.9 7 3 1 9 9 9 0 Cell division protein ZapB DUF4407 PF14362.6 EGO52586.1 - 3.4 6.9 67.9 0.25 10.7 14.4 5.0 2 1 3 5 5 5 0 Domain of unknown function (DUF4407) Ribophorin_II PF05817.14 EGO52587.1 - 1e-31 110.2 0.0 1.3e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II PufQ PF05398.11 EGO52587.1 - 8.8 6.5 6.2 2.5 8.3 1.2 2.4 1 1 0 2 2 2 0 PufQ cytochrome subunit Peptidase_M28 PF04389.17 EGO52588.1 - 6.8e-34 117.3 0.0 1.1e-33 116.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 CDP-OH_P_transf PF01066.21 EGO52589.1 - 1.5e-15 57.7 0.2 1.5e-15 57.7 0.2 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PX PF00787.24 EGO52591.1 - 2.7e-21 75.6 0.0 3.3e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 PX domain AroM PF07302.11 EGO52591.1 - 0.23 10.8 0.0 0.33 10.3 0.0 1.1 1 0 0 1 1 1 0 AroM protein PhoD PF09423.10 EGO52592.1 - 0.00015 20.9 0.0 0.00078 18.6 0.0 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase Peptidase_S8 PF00082.22 EGO52593.1 - 2.4e-37 128.8 3.2 4.5e-37 127.9 3.2 1.4 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EGO52593.1 - 3.8e-27 94.1 1.1 8.5e-27 93.0 1.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 EGO52593.1 - 0.00019 22.1 0.4 0.00061 20.5 0.2 2.0 2 0 0 2 2 2 1 Peptidase S8 pro-domain PX PF00787.24 EGO52594.1 - 6.1e-21 74.5 0.2 3e-20 72.3 0.0 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EGO52594.1 - 1.2e-11 44.6 11.2 5.9e-07 29.3 0.6 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 EGO52594.1 - 4.2e-11 42.9 8.4 1.3e-05 25.0 0.7 2.2 2 0 0 2 2 2 2 BAR domain DUF3140 PF11338.8 EGO52594.1 - 0.0055 17.1 1.1 0.014 15.8 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3140) BAR_3 PF16746.5 EGO52594.1 - 0.1 12.3 5.3 1.6 8.4 0.3 2.7 2 1 0 3 3 3 0 BAR domain of APPL family Sec34 PF04136.15 EGO52594.1 - 0.12 12.2 0.7 0.36 10.7 0.1 2.0 2 0 0 2 2 2 0 Sec34-like family ArdA PF07275.11 EGO52594.1 - 0.26 11.8 0.1 0.26 11.8 0.1 2.2 2 0 0 2 2 2 0 Antirestriction protein (ArdA) XhlA PF10779.9 EGO52594.1 - 0.57 10.4 7.7 2.3 8.5 2.2 2.5 2 0 0 2 2 2 0 Haemolysin XhlA DUF4795 PF16043.5 EGO52594.1 - 0.66 9.5 5.1 0.21 11.2 1.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4407 PF14362.6 EGO52594.1 - 0.68 9.2 4.7 0.3 10.4 0.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EGO52594.1 - 1.1 9.3 9.3 1.7 8.7 0.4 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Occludin_ELL PF07303.13 EGO52594.1 - 1.1 10.0 4.2 1.2 9.9 0.1 2.9 2 1 1 3 3 3 0 Occludin homology domain APG6_N PF17675.1 EGO52594.1 - 1.7 9.2 10.6 3.6 8.1 0.2 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region JIP_LZII PF16471.5 EGO52594.1 - 1.9 8.7 6.0 9.1 6.5 1.1 2.6 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II eIF3_subunit PF08597.10 EGO52594.1 - 9.3 6.1 9.8 0.17 11.7 2.5 1.7 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit LETM1 PF07766.13 EGO52595.1 - 4.1e-106 354.2 2.5 4.1e-106 354.2 2.5 1.6 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 EGO52595.1 - 0.0032 17.2 0.0 0.15 11.9 0.0 3.1 3 0 0 3 3 3 1 SAP domain ADK PF00406.22 EGO52596.1 - 3.3e-37 127.9 0.0 1.7e-19 70.4 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 EGO52596.1 - 2.9e-15 56.0 0.0 5.4e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 EGO52596.1 - 1e-14 55.1 0.0 2.9e-09 37.5 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGO52596.1 - 2.7e-05 24.7 0.0 0.00062 20.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO52596.1 - 0.00021 21.5 0.0 0.00087 19.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGO52596.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Glyco_hydro_76 PF03663.14 EGO52597.1 - 2.1e-18 67.0 2.3 2.6e-10 40.4 0.2 3.1 2 1 0 2 2 2 2 Glycosyl hydrolase family 76 LicD PF04991.13 EGO52599.1 - 6.5e-16 59.2 0.3 9.3e-16 58.7 0.3 1.2 1 0 0 1 1 1 1 LicD family MFMR_assoc PF16596.5 EGO52601.1 - 0.092 13.2 0.6 0.25 11.8 0.6 1.7 1 0 0 1 1 1 0 Disordered region downstream of MFMR IHABP4_N PF16174.5 EGO52601.1 - 3.5 8.2 18.2 8.6 6.9 2.9 2.4 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Glyco_hydro_18 PF00704.28 EGO52603.1 - 5.5e-69 233.3 0.0 9.3e-69 232.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LRR_6 PF13516.6 EGO52605.1 - 5.5e-08 32.2 10.4 0.016 15.2 0.0 6.1 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 EGO52605.1 - 6.3e-06 26.4 11.9 0.067 13.6 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGO52605.1 - 0.002 18.4 1.5 11 7.0 0.1 5.1 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 EGO52605.1 - 0.0046 16.7 13.5 5 7.0 0.2 5.2 4 1 0 4 4 4 2 Leucine rich repeat Pep1_7 PF17232.2 EGO52605.1 - 1.1 9.8 5.9 2.2 8.8 5.9 1.5 1 0 0 1 1 1 0 Elicitor peptide 1-7 RIC3 PF15361.6 EGO52605.1 - 1.7 9.0 4.7 2.8 8.3 4.7 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 SDA1 PF05285.12 EGO52605.1 - 2 7.8 17.3 3.5 7.0 17.3 1.3 1 0 0 1 1 1 0 SDA1 LETM1 PF07766.13 EGO52605.1 - 3.2 7.0 5.6 0.49 9.7 0.1 2.1 2 0 0 2 2 2 0 LETM1-like protein zf-H2C2_2 PF13465.6 EGO52606.1 - 2.1e-06 27.9 10.0 3.4e-06 27.2 1.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 EGO52606.1 - 5.2e-06 26.6 8.5 2.6e-05 24.4 0.3 3.3 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGO52606.1 - 2.3e-05 24.2 0.5 0.062 13.3 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 EGO52606.1 - 7.2e-05 23.3 7.7 0.15 12.7 0.0 4.0 3 1 1 4 4 4 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 EGO52606.1 - 0.00038 21.0 3.7 0.012 16.4 0.3 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EGO52606.1 - 0.18 11.6 0.2 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 EGO52606.1 - 0.33 11.3 1.1 6.5 7.2 0.2 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 EGO52606.1 - 0.42 10.4 1.9 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Fe_hyd_lg_C PF02906.14 EGO52608.1 - 5.4e-49 167.1 0.0 1.2e-48 165.9 0.0 1.6 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SUZ PF12752.7 EGO52609.1 - 8.8e-05 23.2 10.6 8.8e-05 23.2 10.6 2.8 3 1 0 3 3 3 1 SUZ domain ARGLU PF15346.6 EGO52609.1 - 0.42 10.5 17.1 0.057 13.3 8.6 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 XAP5 PF04921.14 EGO52609.1 - 2.1 8.1 9.4 0.47 10.2 5.1 1.8 2 0 0 2 2 2 0 XAP5, circadian clock regulator DUF1754 PF08555.10 EGO52609.1 - 3.1 8.6 12.3 30 5.5 8.0 2.4 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Pkinase PF00069.25 EGO52611.1 - 7.6e-68 228.7 0.0 1e-67 228.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO52611.1 - 1.2e-30 106.7 0.0 1.7e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGO52611.1 - 3.1e-14 53.4 1.9 3.1e-13 50.2 0.3 3.1 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 EGO52611.1 - 1.8e-09 37.4 0.0 8.4e-09 35.1 0.0 1.9 1 1 0 2 2 2 1 Kinase-like C2 PF00168.30 EGO52611.1 - 4.1e-07 30.2 0.0 7.9e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 C2 domain Haspin_kinase PF12330.8 EGO52611.1 - 0.0019 17.2 0.1 0.0042 16.1 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGO52611.1 - 0.017 14.5 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO52611.1 - 0.034 14.1 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Adeno_E3_15_3 PF03307.14 EGO52611.1 - 0.059 13.3 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Adenovirus 15.3kD protein in E3 region FTA2 PF13095.6 EGO52611.1 - 0.068 12.8 0.9 5.3 6.6 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EGO52611.1 - 0.074 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EGO52611.1 - 0.11 11.3 0.4 0.56 8.9 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase ATP_sub_h PF10775.9 EGO52612.1 - 2.3e-26 91.5 0.8 3.9e-26 90.8 0.8 1.4 1 0 0 1 1 1 1 ATP synthase complex subunit h CDH-cyt PF16010.5 EGO52613.1 - 5e-22 78.5 3.3 8.5e-22 77.7 3.3 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 EGO52613.1 - 9.6e-07 29.1 0.1 2e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 EGO52613.1 - 0.1 12.4 9.0 0.031 14.1 5.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) ABC2_membrane_5 PF13346.6 EGO52613.1 - 0.67 9.5 5.1 1 8.9 5.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Pkinase PF00069.25 EGO52614.1 - 2.9e-69 233.4 0.0 3.6e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO52614.1 - 8.3e-31 107.2 0.0 1.1e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO52614.1 - 9.7e-05 21.5 0.1 0.00014 21.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGO52614.1 - 0.012 14.9 0.1 0.033 13.5 0.1 1.7 1 1 1 2 2 2 0 Kinase-like Pkinase_C PF00433.24 EGO52614.1 - 0.025 15.3 0.0 0.073 13.8 0.0 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain Pkinase_fungal PF17667.1 EGO52614.1 - 0.052 12.3 0.1 0.14 10.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 EGO52614.1 - 0.12 12.2 0.0 2.9 7.8 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 EGO52616.1 - 4.1e-39 131.9 17.1 8.9e-09 35.8 1.7 7.6 7 1 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.11 EGO52616.1 - 5e-16 57.9 2.3 9.4e-16 57.1 2.3 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 EGO52616.1 - 3.7e-14 52.8 1.2 0.02 15.2 0.0 6.3 4 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO52616.1 - 0.0024 16.9 0.0 14 4.5 0.0 4.3 2 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGO52616.1 - 0.035 13.4 0.0 15 4.8 0.0 3.2 3 0 0 3 3 3 0 WD40-like domain Nbas_N PF15492.6 EGO52616.1 - 0.091 12.1 0.0 2.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Cyclin_N PF00134.23 EGO52617.1 - 3.4e-08 33.3 1.4 5.6e-08 32.6 0.2 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain FliJ PF02050.16 EGO52617.1 - 0.16 12.2 4.5 0.91 9.8 0.9 2.8 3 1 0 3 3 3 0 Flagellar FliJ protein Dus PF01207.17 EGO52618.1 - 2e-28 99.4 0.0 8.2e-24 84.2 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) AIRC PF00731.20 EGO52619.1 - 2.5e-59 199.1 0.5 4.9e-59 198.2 0.5 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EGO52619.1 - 2e-48 164.2 0.0 3.1e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EGO52619.1 - 3.4e-13 49.1 0.0 6.9e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EGO52619.1 - 3.6e-07 29.9 0.0 7.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 EGO52619.1 - 6.1e-05 22.6 0.0 0.0025 17.3 0.0 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PrpR_N PF06506.11 EGO52619.1 - 0.00084 19.0 0.1 0.0027 17.3 0.0 1.9 2 0 0 2 2 2 1 Propionate catabolism activator 2-Hacid_dh_C PF02826.19 EGO52619.1 - 0.0064 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 EGO52619.1 - 0.018 15.6 0.0 2.4 8.7 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain UPF0139 PF03669.13 EGO52620.1 - 1.1e-08 34.8 0.0 1.5e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) GDI PF00996.18 EGO52622.1 - 4.7e-25 88.0 0.0 6.8e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 GDP dissociation inhibitor Rad21_Rec8_N PF04825.13 EGO52623.1 - 3.9e-31 107.5 0.0 6.7e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EGO52623.1 - 6e-11 41.5 0.0 1.4e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 EGO52623.1 - 0.021 14.7 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Segregation and condensation protein ScpA ALO PF04030.14 EGO52625.1 - 4.8e-97 324.8 1.3 6.2e-97 324.5 1.3 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EGO52625.1 - 1.4e-30 105.8 0.1 2.4e-30 105.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pkinase PF00069.25 EGO52626.1 - 4.9e-54 183.5 0.1 7.1e-34 117.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO52626.1 - 4.7e-35 121.1 0.0 6.5e-34 117.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO52626.1 - 0.00027 20.4 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like HOOK PF05622.12 EGO52626.1 - 0.033 12.4 6.2 0.058 11.5 6.2 1.3 1 0 0 1 1 1 0 HOOK protein APH PF01636.23 EGO52626.1 - 0.081 12.8 0.1 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3896 PF13035.6 EGO52626.1 - 0.093 12.9 1.1 0.28 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) Pkinase_fungal PF17667.1 EGO52626.1 - 0.11 11.2 0.3 0.51 9.0 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase DUF4140 PF13600.6 EGO52626.1 - 5 7.6 7.1 0.51 10.8 0.7 2.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) FAM184 PF15665.5 EGO52626.1 - 6.4 6.5 11.2 0.53 10.0 6.3 1.6 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B BTB PF00651.31 EGO52627.1 - 1.3e-27 96.2 0.3 2.7e-13 50.1 0.4 3.3 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.7 EGO52627.1 - 8.5e-08 32.7 0.0 2.9e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO52627.1 - 7.5e-06 26.4 0.1 1.7e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO52627.1 - 1.8e-05 24.8 0.1 0.13 12.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EGO52627.1 - 2.4e-05 24.5 0.0 8.9e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGO52627.1 - 2.6e-05 24.5 0.1 0.0025 18.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat zf-C2H2 PF00096.26 EGO52630.1 - 1.1e-08 35.1 12.2 0.00048 20.4 2.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO52630.1 - 1.1e-05 25.6 10.2 3.4e-05 24.1 2.0 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO52630.1 - 9.1e-05 23.0 11.4 0.094 13.6 2.4 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGO52630.1 - 0.011 15.8 0.9 0.011 15.8 0.9 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 EGO52630.1 - 0.027 14.9 3.7 0.074 13.5 1.6 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGO52630.1 - 0.068 13.5 4.5 0.079 13.3 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 EGO52630.1 - 0.27 11.4 2.2 2.2 8.5 0.8 2.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-RRN7 PF11781.8 EGO52632.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Lipase_GDSL_2 PF13472.6 EGO52633.1 - 2.1e-11 44.5 2.2 4e-11 43.6 2.2 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGO52633.1 - 6.6e-09 36.0 0.0 1.4e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BORCS6 PF10157.9 EGO52635.1 - 0.012 15.8 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 AAA_13 PF13166.6 EGO52635.1 - 0.02 13.6 0.1 0.022 13.4 0.1 1.0 1 0 0 1 1 1 0 AAA domain FlgD_ig PF13860.6 EGO52635.1 - 0.079 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 FlgD Ig-like domain DUF1664 PF07889.12 EGO52635.1 - 0.11 12.5 0.2 0.19 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Glyco_hydro2_C5 PF18565.1 EGO52635.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 DUF2120 PF09893.9 EGO52635.1 - 0.15 12.2 0.1 0.2 11.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) PHD PF00628.29 EGO52636.1 - 6.6e-12 45.1 6.1 6.6e-12 45.1 6.1 2.3 2 0 0 2 2 2 1 PHD-finger zf-HIT PF04438.16 EGO52636.1 - 4.3 7.3 8.0 0.16 11.8 1.2 2.2 2 0 0 2 2 2 0 HIT zinc finger SCO1-SenC PF02630.14 EGO52637.1 - 3.8e-51 172.5 0.0 5.7e-51 171.9 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EGO52637.1 - 3.3e-06 27.0 0.0 6.7e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EGO52637.1 - 0.0012 19.1 0.0 0.0034 17.7 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EGO52637.1 - 0.0061 16.3 0.0 0.082 12.6 0.0 2.1 1 1 0 1 1 1 1 Redoxin Choline_kinase PF01633.20 EGO52638.1 - 5.9e-69 231.9 0.0 1.2e-68 230.9 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 EGO52638.1 - 2.5e-20 71.9 0.0 4.8e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 EGO52638.1 - 1.8e-05 24.8 0.0 3.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3433 PF11915.8 EGO52639.1 - 2.4e-29 101.6 14.8 1.3e-28 99.3 2.2 4.0 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) TMPIT PF07851.13 EGO52641.1 - 0.48 9.6 2.0 0.79 8.9 2.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein ST7 PF04184.12 EGO52641.1 - 1 7.7 2.5 1.6 7.1 2.5 1.2 1 0 0 1 1 1 0 ST7 protein CENP-Q PF13094.6 EGO52641.1 - 6 7.0 24.8 0.033 14.4 7.6 2.7 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Hydrolase_6 PF13344.6 EGO52642.1 - 1.1e-25 89.6 0.0 2.7e-25 88.4 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO52642.1 - 1.2e-15 57.3 0.0 2.9e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EGO52642.1 - 3.5e-05 24.2 0.0 3 8.1 0.0 4.0 2 1 2 4 4 4 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGO52642.1 - 0.18 11.9 0.0 22 5.1 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF4834 PF16118.5 EGO52643.1 - 0.96 10.5 4.4 0.39 11.7 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Dicty_REP PF05086.12 EGO52643.1 - 1.7 6.5 3.5 2.4 6.0 3.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein OPT PF03169.15 EGO52644.1 - 1e-186 622.2 53.3 1.2e-186 622.0 53.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MoaE PF02391.17 EGO52646.1 - 2.1e-36 124.6 0.0 2.7e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 MoaE protein G-patch PF01585.23 EGO52647.1 - 1.2e-10 41.1 2.6 3.7e-10 39.5 2.6 1.9 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 EGO52647.1 - 2.8e-06 26.5 1.9 6.2e-06 25.4 1.9 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 EGO52647.1 - 6.9e-05 22.6 0.3 0.088 12.6 0.0 3.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 EGO52647.1 - 0.00052 20.1 3.1 0.00052 20.1 3.1 2.4 1 1 1 2 2 2 1 G-patch domain zf-C2H2_2 PF12756.7 EGO52647.1 - 0.13 12.6 1.8 4.1 7.8 0.7 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Asp PF00026.23 EGO52648.1 - 6e-66 223.0 3.3 8.5e-66 222.5 3.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO52648.1 - 1.7e-12 47.9 3.4 1.1e-10 42.0 3.4 2.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO52648.1 - 0.00047 20.8 0.6 4.1 8.1 0.0 3.6 3 0 0 3 3 3 2 Aspartyl protease DPCD PF14913.6 EGO52649.1 - 0.023 14.1 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 DPCD protein family DUF3826 PF12875.7 EGO52649.1 - 0.034 14.3 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) SAICAR_synt PF01259.18 EGO52651.1 - 6e-61 206.2 0.0 6.7e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase HATPase_c PF02518.26 EGO52653.1 - 5e-22 78.5 0.0 1.4e-21 77.1 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGO52653.1 - 3.4e-16 59.4 1.4 2.1e-11 43.9 0.0 3.5 3 0 0 3 3 3 2 Response regulator receiver domain PAS PF00989.25 EGO52653.1 - 6.8e-11 42.2 0.0 0.00018 21.5 0.0 3.8 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 EGO52653.1 - 1e-10 41.8 0.0 0.015 15.5 0.0 3.9 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.10 EGO52653.1 - 1.9e-09 37.7 0.0 0.14 12.4 0.0 5.1 4 0 0 4 4 4 2 PAS fold HisKA PF00512.25 EGO52653.1 - 3.8e-09 36.5 0.0 2.9e-08 33.6 0.0 2.6 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 EGO52653.1 - 1.6e-08 34.3 0.0 0.00043 20.2 0.0 3.8 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 EGO52653.1 - 7.8e-07 29.3 0.0 0.02 15.2 0.0 3.6 2 1 0 2 2 2 2 PAS fold RR_TM4-6 PF06459.12 EGO52653.1 - 1.8 8.3 11.2 0.4 10.5 7.4 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF3449 PF11931.8 EGO52653.1 - 1.9 8.3 5.5 5.4 6.8 5.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) NPR3 PF03666.13 EGO52653.1 - 8.9 5.0 9.9 15 4.2 9.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Dabb PF07876.12 EGO52654.1 - 8.7e-16 58.3 0.0 9.7e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Prominin PF05478.11 EGO52655.1 - 0.31 9.0 3.9 0.37 8.7 3.3 1.3 1 1 0 1 1 1 0 Prominin RNase_PH PF01138.21 EGO52658.1 - 2e-20 73.6 0.0 4.1e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Radial_spoke PF04712.12 EGO52658.1 - 0.0085 15.1 0.1 0.011 14.8 0.1 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein RNase_PH_C PF03725.15 EGO52658.1 - 0.019 15.0 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Abhydrolase_1 PF00561.20 EGO52659.1 - 6.1e-12 45.7 0.1 3e-11 43.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO52659.1 - 1.6e-10 40.7 0.0 5.5e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGO52659.1 - 6.4e-09 36.7 0.4 2.9e-08 34.6 0.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EGO52659.1 - 0.048 13.5 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 EGO52659.1 - 0.058 13.2 0.3 1.4 8.6 0.2 2.7 2 1 0 2 2 2 0 Alpha/beta hydrolase family BAAT_C PF08840.11 EGO52659.1 - 0.12 12.3 0.1 2 8.3 0.0 2.3 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal L51_S25_CI-B8 PF05047.16 EGO52661.1 - 8.5e-12 44.8 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain CaM_binding PF07839.11 EGO52661.1 - 0.094 13.5 0.0 0.1 13.4 0.0 1.2 1 0 0 1 1 1 0 Plant calmodulin-binding domain MPC PF03650.13 EGO52662.1 - 6e-50 168.0 1.1 9.2e-50 167.4 1.1 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers TadE PF07811.12 EGO52662.1 - 0.21 11.9 0.9 1.3 9.4 0.0 2.4 3 0 0 3 3 3 0 TadE-like protein Fumble PF03630.14 EGO52663.1 - 5.9e-141 469.4 0.0 7.4e-141 469.1 0.0 1.1 1 0 0 1 1 1 1 Fumble RGS PF00615.19 EGO52664.1 - 1.6e-05 25.2 0.1 0.0015 18.8 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF1348 PF07080.11 EGO52665.1 - 1e-64 216.3 9.3 1.3e-64 216.0 9.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) DUF4440 PF14534.6 EGO52665.1 - 4.8e-06 26.9 0.1 7.1e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 EGO52665.1 - 2.3e-05 25.0 0.8 3.2e-05 24.5 0.8 1.2 1 0 0 1 1 1 1 SnoaL-like domain Redoxin PF08534.10 EGO52666.1 - 1.4e-37 128.7 0.1 1.5e-37 128.5 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGO52666.1 - 2.1e-10 40.6 0.1 2.7e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Ribosomal_L24e PF01246.20 EGO52667.1 - 1.3e-28 99.0 0.1 1.3e-28 99.0 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.12 EGO52667.1 - 0.045 13.3 1.6 0.056 13.0 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) A_deamin PF02137.18 EGO52668.1 - 3.1e-28 99.2 0.0 9.8e-28 97.5 0.0 1.8 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF1970 PF09301.10 EGO52668.1 - 0.17 12.1 1.7 1 9.7 0.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1970) NAC PF01849.18 EGO52669.1 - 2.6e-23 81.8 0.6 1e-22 79.8 0.3 2.0 2 0 0 2 2 2 1 NAC domain CBP4 PF07960.11 EGO52670.1 - 3.9e-31 107.6 1.4 5e-31 107.2 1.4 1.1 1 0 0 1 1 1 1 CBP4 F-box-like PF12937.7 EGO52671.1 - 2.4e-11 43.4 0.2 4.3e-11 42.5 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO52671.1 - 0.00037 20.3 0.3 0.001 18.9 0.3 1.8 1 1 0 1 1 1 1 F-box domain PRiA4_ORF3 PF07929.11 EGO52671.1 - 0.036 13.8 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein MttA_Hcf106 PF02416.16 EGO52671.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 mttA/Hcf106 family Cation_efflux PF01545.21 EGO52672.1 - 6.8e-44 150.0 14.9 1.9e-43 148.5 14.9 1.6 1 1 0 1 1 1 1 Cation efflux family Macoilin PF09726.9 EGO52672.1 - 0.25 9.9 3.6 0.3 9.6 3.6 1.1 1 0 0 1 1 1 0 Macoilin family HTH_39 PF14090.6 EGO52673.1 - 0.032 14.0 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain CNOT1_CAF1_bind PF16415.5 EGO52673.1 - 0.13 11.7 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Glycos_transf_N PF04413.16 EGO52674.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) VIT1 PF01988.19 EGO52674.1 - 0.22 11.4 1.1 0.36 10.7 1.1 1.3 1 0 0 1 1 1 0 VIT family Zn_clus PF00172.18 EGO52674.1 - 0.23 11.6 4.0 0.47 10.6 4.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.14 EGO52674.1 - 1.3 7.2 6.7 2 6.6 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EGO52674.1 - 1.9 8.3 11.0 3.6 7.3 11.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rib_recp_KP_reg PF05104.12 EGO52674.1 - 2.2 9.3 14.0 0.12 13.4 6.8 2.1 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Tim54 PF11711.8 EGO52674.1 - 3.1 6.5 8.7 5 5.8 8.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 EGO52674.1 - 3.4 6.4 10.9 6 5.5 10.9 1.3 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 EGO52674.1 - 5 5.5 8.9 6.7 5.1 8.9 1.3 1 0 0 1 1 1 0 Macoilin family DUF4746 PF15928.5 EGO52674.1 - 5.8 6.3 11.9 10 5.5 11.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PLA2_B PF01735.18 EGO52676.1 - 2.9e-207 688.9 1.2 3.5e-207 688.7 1.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Lyase_8 PF02278.18 EGO52677.1 - 0.16 11.4 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, super-sandwich domain Histidinol_dh PF00815.20 EGO52678.1 - 2e-158 527.7 7.9 2.7e-158 527.3 7.9 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 EGO52678.1 - 1.1e-24 86.0 0.1 2.2e-24 85.0 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EGO52678.1 - 9.5e-14 51.6 0.3 9.5e-14 51.6 0.3 2.5 2 1 1 3 3 3 1 Phosphoribosyl-ATP pyrophosphohydrolase Phasin_2 PF09361.10 EGO52678.1 - 0.04 14.2 2.9 10 6.4 0.2 3.8 3 0 0 3 3 3 0 Phasin protein TFIID-31kDa PF02291.15 EGO52679.1 - 7.7e-40 135.8 0.0 8.9e-40 135.6 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit LNS2 PF08235.13 EGO52680.1 - 1.9e-93 312.1 0.0 2.7e-93 311.6 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EGO52680.1 - 6.6e-43 144.8 0.0 1.7e-42 143.5 0.0 1.8 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 EGO52680.1 - 0.0023 17.5 0.0 0.22 11.0 0.0 2.5 2 0 0 2 2 2 2 HAD superfamily, subfamily IIIB (Acid phosphatase) fn3 PF00041.21 EGO52682.1 - 2.6e-07 30.9 0.0 5.9e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain ADIP PF11559.8 EGO52682.1 - 0.46 10.6 36.9 1.7 8.7 8.6 3.7 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding TACC_C PF05010.14 EGO52682.1 - 7.1 6.4 32.8 8.1 6.2 18.0 2.4 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cmc1 PF08583.10 EGO52683.1 - 1e-16 60.7 0.7 1e-16 60.7 0.7 1.8 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 EGO52683.1 - 0.087 12.9 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 EGO52683.1 - 0.38 10.9 2.2 2.4 8.4 0.2 2.2 1 1 1 2 2 2 0 CHCH domain DUF3128 PF11326.8 EGO52683.1 - 6.5 7.2 7.3 4.4e+02 1.3 7.3 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Glyco_hydro_47 PF01532.20 EGO52684.1 - 1.7e-170 567.9 0.0 1.9e-170 567.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 EGO52684.1 - 0.1 11.1 0.0 2.5 6.5 0.0 2.3 2 1 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Utp11 PF03998.13 EGO52685.1 - 2.2e-61 207.9 28.5 2.6e-61 207.7 28.5 1.1 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 EGO52685.1 - 0.0076 15.6 7.9 0.063 12.6 0.5 2.2 2 0 0 2 2 2 2 SMODS and SLOG-associating 2TM effector domain family 5 DAO PF01266.24 EGO52687.1 - 7e-37 127.8 0.2 9.6e-37 127.4 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO52687.1 - 0.019 14.0 0.1 0.028 13.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 EGO52687.1 - 0.034 14.6 0.0 0.062 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 EGO52687.1 - 0.037 14.6 0.1 0.073 13.6 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGO52687.1 - 0.044 13.1 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 EGO52687.1 - 0.07 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Maf PF02545.14 EGO52688.1 - 4.4e-51 173.0 0.0 5.1e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein VbhA PF18495.1 EGO52688.1 - 0.056 13.3 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Antitoxin VbhA tRNA-synt_2b PF00587.25 EGO52689.1 - 5.2e-34 117.8 0.0 7.3e-32 110.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGO52689.1 - 9e-09 35.4 0.0 1.8e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain SprB PF13573.6 EGO52689.1 - 0.4 10.5 1.5 0.81 9.5 1.5 1.5 1 0 0 1 1 1 0 SprB repeat LOH1CR12 PF10158.9 EGO52690.1 - 0.032 14.3 1.1 0.09 12.8 1.1 1.7 1 0 0 1 1 1 0 Tumour suppressor protein ATG101 PF07855.12 EGO52690.1 - 0.1 12.6 1.1 0.21 11.5 1.1 1.5 1 0 0 1 1 1 0 Autophagy-related protein 101 DUF148 PF02520.17 EGO52690.1 - 3.4 7.8 6.6 5.4 7.2 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF148 Amidohydro_1 PF01979.20 EGO52691.1 - 1.1e-77 261.7 1.3 1.9e-77 260.9 0.7 1.6 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 EGO52691.1 - 5.5e-55 184.9 5.2 1.1e-54 183.9 3.3 2.2 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 EGO52691.1 - 1e-42 144.1 0.3 3e-42 142.6 0.1 1.9 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 EGO52691.1 - 3e-40 136.5 0.1 5.9e-40 135.6 0.1 1.5 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 EGO52691.1 - 8.6e-11 42.0 1.2 1.5e-07 31.2 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family HMG_box PF00505.19 EGO52692.1 - 3.9e-06 27.2 0.1 1.6e-05 25.2 0.1 2.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO52692.1 - 0.00098 19.7 0.1 0.00098 19.7 0.1 2.9 3 0 0 3 3 3 1 HMG-box domain DUF2624 PF11116.8 EGO52692.1 - 0.097 13.6 1.2 0.2 12.5 0.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2624) Roughex PF06020.11 EGO52692.1 - 5.7 5.9 15.9 8.2 5.4 15.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Het-C PF07217.11 EGO52693.1 - 9.9e-234 777.0 0.0 1.2e-233 776.8 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Pkinase PF00069.25 EGO52694.1 - 1e-65 221.7 0.1 1.2e-65 221.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO52694.1 - 5.6e-19 68.4 0.0 8e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO52694.1 - 1.9e-08 34.6 0.0 4e-06 26.9 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGO52694.1 - 0.0075 15.1 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGO52694.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGO52694.1 - 0.028 13.8 0.2 0.055 12.8 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGO52694.1 - 0.052 13.1 0.1 0.052 13.1 0.1 2.0 3 0 0 3 3 3 0 Choline/ethanolamine kinase Scm3 PF10384.9 EGO52695.1 - 1.3e-20 72.9 0.0 2.5e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 APG6 PF04111.12 EGO52696.1 - 2.2e-70 236.2 0.0 1e-69 234.1 0.0 2.0 2 1 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 EGO52696.1 - 5.8e-34 117.5 21.4 1.3e-33 116.3 21.4 1.6 1 0 0 1 1 1 1 Apg6 coiled-coil region FapA PF03961.13 EGO52696.1 - 0.0086 14.7 6.7 0.012 14.2 6.7 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A CdvA PF18822.1 EGO52696.1 - 0.024 14.5 15.5 0.22 11.4 9.5 2.7 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Rpr2 PF04032.16 EGO52696.1 - 0.15 12.4 1.3 0.34 11.2 0.1 2.4 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF1664 PF07889.12 EGO52696.1 - 0.41 10.7 2.0 0.7 9.9 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) AAA PF00004.29 EGO52697.1 - 5e-12 46.4 0.0 8.6e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cwf_Cwc_15 PF04889.12 EGO52697.1 - 0.0036 17.1 4.9 0.0036 17.1 4.9 1.7 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein AAA_16 PF13191.6 EGO52697.1 - 0.0038 17.6 0.0 0.0078 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain CPT PF07931.12 EGO52697.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Herpes_pp85 PF04637.12 EGO52697.1 - 0.16 10.3 1.3 0.42 9.0 1.3 1.6 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) AAA_22 PF13401.6 EGO52697.1 - 0.19 12.0 0.1 0.5 10.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain THOC2_N PF16134.5 EGO52697.1 - 0.28 9.8 2.6 0.48 9.0 2.6 1.3 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DNA_pol_phi PF04931.13 EGO52697.1 - 1.1 7.2 12.2 1.7 6.7 12.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EGO52697.1 - 3.5 5.7 7.9 6.4 4.9 7.9 1.3 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EGO52697.1 - 6.2 6.0 12.8 13 5.0 12.8 1.4 1 0 0 1 1 1 0 NOA36 protein DUF5470 PF17564.2 EGO52697.1 - 8.5 6.7 6.9 36 4.6 6.9 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5470) Zn_clus PF00172.18 EGO52698.1 - 5.8e-08 32.7 11.1 1e-07 32.0 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGO52698.1 - 0.0002 20.5 0.0 0.00045 19.3 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain NifW PF03206.14 EGO52698.1 - 0.029 14.9 0.3 0.063 13.8 0.3 1.5 1 0 0 1 1 1 0 Nitrogen fixation protein NifW Clusterin PF01093.17 EGO52698.1 - 0.18 10.8 3.1 0.27 10.3 3.1 1.1 1 0 0 1 1 1 0 Clusterin AlaDh_PNT_N PF05222.15 EGO52699.1 - 3.9e-30 104.9 0.0 6.3e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EGO52699.1 - 0.0048 16.2 0.0 0.014 14.7 0.0 1.7 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IMPDH PF00478.25 EGO52700.1 - 9e-130 432.7 4.5 1e-129 432.5 4.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EGO52700.1 - 2.7e-15 56.5 0.2 5.6e-07 29.9 0.1 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 EGO52700.1 - 2.2e-08 33.9 3.6 0.0046 16.4 4.2 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EGO52700.1 - 3.2e-08 33.0 2.0 2.8e-07 29.9 0.7 2.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 EGO52700.1 - 0.0017 17.9 4.4 9.5 5.6 0.1 2.6 2 1 0 2 2 2 1 Histidine biosynthesis protein PK PF00224.21 EGO52700.1 - 0.01 14.7 0.0 0.035 13.0 0.0 1.8 1 1 0 1 1 1 0 Pyruvate kinase, barrel domain ThiG PF05690.14 EGO52700.1 - 0.021 14.1 0.3 0.049 12.9 0.3 1.6 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG YpsA PF06908.11 EGO52700.1 - 0.022 14.8 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family RasGAP PF00616.19 EGO52701.1 - 1.7e-55 188.0 0.0 5e-55 186.4 0.0 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EGO52701.1 - 1.9e-50 170.6 4.4 1.9e-49 167.4 4.4 2.9 1 0 0 1 1 1 1 RasGAP C-terminus IQ PF00612.27 EGO52701.1 - 1.2e-28 96.1 38.5 0.06 13.2 0.2 15.9 16 0 0 16 16 16 10 IQ calmodulin-binding motif CH PF00307.31 EGO52701.1 - 2.1e-10 40.7 0.0 8.5e-10 38.8 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CDT1_C PF16679.5 EGO52701.1 - 0.12 12.8 2.2 0.75 10.3 1.6 2.9 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain GIT_SHD PF08518.11 EGO52702.1 - 1.1e-24 85.7 7.1 3.8e-13 48.8 3.5 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT PSII_Pbs27 PF13326.6 EGO52702.1 - 0.11 12.8 7.8 0.24 11.7 1.9 3.2 2 1 1 3 3 3 0 Photosystem II Pbs27 Cep57_MT_bd PF06657.13 EGO52702.1 - 0.14 12.7 0.1 0.14 12.7 0.1 3.6 2 1 1 3 3 2 0 Centrosome microtubule-binding domain of Cep57 UPF0242 PF06785.11 EGO52702.1 - 0.18 11.9 32.7 0.015 15.4 13.3 2.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 EGO52702.1 - 0.57 8.6 12.5 1.4 7.3 12.5 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 EGO52702.1 - 0.67 9.3 26.9 1.1 8.6 6.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Prominin PF05478.11 EGO52702.1 - 0.69 7.8 11.1 1.6 6.6 11.1 1.5 1 0 0 1 1 1 0 Prominin CLZ PF16526.5 EGO52702.1 - 0.98 9.8 25.1 0.22 11.9 0.8 4.2 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DHR10 PF18595.1 EGO52702.1 - 1.5 8.9 38.0 2.6 8.1 14.8 3.3 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain ParD_antitoxin PF03693.14 EGO52702.1 - 1.8 9.0 4.8 2.2 8.8 0.9 3.0 3 1 0 3 3 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH THP2 PF09432.10 EGO52702.1 - 1.9 8.5 10.1 0.084 12.9 0.9 2.7 2 1 0 2 2 2 0 Tho complex subunit THP2 DUF4686 PF15742.5 EGO52702.1 - 2.2 7.3 33.9 19 4.3 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4686) Syntaxin_2 PF14523.6 EGO52702.1 - 3.9 7.9 30.2 0.19 12.1 5.7 5.7 5 1 1 6 6 6 0 Syntaxin-like protein APG6_N PF17675.1 EGO52702.1 - 4.2 7.9 40.6 3 8.4 28.8 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 EGO52702.1 - 6.7 6.0 33.4 2.6 7.4 10.7 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EGO52702.1 - 8.8 5.1 33.1 1.4 7.7 20.2 2.7 2 1 1 3 3 3 0 Spc7 kinetochore protein Ssu72 PF04722.13 EGO52704.1 - 1.1e-83 279.5 0.0 1.3e-83 279.3 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SH3_1 PF00018.28 EGO52705.1 - 2.7e-10 39.7 0.1 5.1e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGO52705.1 - 3.2e-08 33.3 0.2 7e-08 32.2 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGO52705.1 - 0.0013 18.4 0.0 0.0043 16.7 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Menin PF05053.13 EGO52705.1 - 1.6 7.0 6.8 2.4 6.4 6.8 1.2 1 0 0 1 1 1 0 Menin NAD_binding_1 PF00175.21 EGO52706.1 - 4.2e-32 111.0 0.0 6.7e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGO52706.1 - 4.8e-24 84.6 0.0 8.6e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGO52706.1 - 1.7e-08 34.7 0.0 9e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EGO52706.1 - 0.016 15.4 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF3807 PF12720.7 EGO52707.1 - 1.6e-62 211.1 11.6 1.8e-62 210.8 11.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Ribosomal_60s PF00428.19 EGO52707.1 - 0.017 15.7 2.6 0.068 13.8 0.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Zn_clus PF00172.18 EGO52708.1 - 9.5e-09 35.2 11.8 1.5e-08 34.6 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGO52708.1 - 2.6e-08 33.2 0.0 1.2e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4529 PF15032.6 EGO52708.1 - 0.86 8.7 6.0 1.7 7.7 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) MARVEL PF01284.23 EGO52709.1 - 4.5e-06 26.7 11.1 4.5e-06 26.7 11.1 2.3 2 1 0 2 2 2 1 Membrane-associating domain ODV-E18 PF10717.9 EGO52709.1 - 0.12 12.3 1.8 4.3 7.3 0.1 2.8 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Holin_SPP1 PF04688.13 EGO52709.1 - 0.27 11.4 2.9 0.6 10.3 2.9 1.5 1 0 0 1 1 1 0 SPP1 phage holin Androgen_recep PF02166.16 EGO52709.1 - 5.5 5.7 25.1 11 4.8 25.1 1.4 1 0 0 1 1 1 0 Androgen receptor TFIIA PF03153.13 EGO52709.1 - 5.9 6.8 27.5 8.2 6.3 27.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EGO52709.1 - 8.6 4.5 16.3 11 4.1 16.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFR_dimer PF04253.15 EGO52710.1 - 8.2e-36 122.8 0.1 1.6e-35 121.8 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EGO52710.1 - 6.1e-18 65.2 0.0 1.3e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EGO52710.1 - 7.6e-11 41.9 0.2 2.1e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 PA domain Dor1 PF04124.12 EGO52710.1 - 0.32 9.6 0.8 0.43 9.2 0.8 1.2 1 0 0 1 1 1 0 Dor1-like family MFS_1 PF07690.16 EGO52711.1 - 4.4e-45 154.1 21.8 2.2e-30 105.8 6.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO52711.1 - 1.3e-11 44.0 4.6 1.3e-11 44.0 4.6 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EGO52711.1 - 0.013 14.0 0.3 0.021 13.2 0.3 1.3 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) NuiA PF07924.11 EGO52712.1 - 0.073 13.5 0.3 0.33 11.4 0.0 2.0 1 1 1 2 2 2 0 Nuclease A inhibitor-like protein Atg14 PF10186.9 EGO52713.1 - 6.7e-82 275.1 0.0 8.9e-82 274.7 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EGO52713.1 - 0.01 14.7 3.7 0.021 13.7 3.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 EGO52713.1 - 0.056 12.7 2.3 0.082 12.1 2.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein ADIP PF11559.8 EGO52713.1 - 0.07 13.2 8.8 0.11 12.5 8.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding BST2 PF16716.5 EGO52713.1 - 1.1 9.9 7.2 0.97 10.1 0.1 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 GrpE PF01025.19 EGO52713.1 - 3.1 7.4 6.3 5.3 6.7 6.3 1.3 1 0 0 1 1 1 0 GrpE NUP50 PF08911.11 EGO52714.1 - 0.02 15.5 8.4 0.026 15.2 0.6 2.9 1 1 1 2 2 2 0 NUP50 (Nucleoporin 50 kDa) SinI PF08671.10 EGO52714.1 - 0.19 11.6 0.1 0.37 10.6 0.1 1.4 1 0 0 1 1 1 0 Anti-repressor SinI Spc7_N PF15402.6 EGO52715.1 - 2.5e-175 585.4 74.5 2.6e-125 419.8 37.8 3.5 1 1 2 3 3 3 3 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 EGO52715.1 - 9.5e-125 415.6 9.6 9.5e-125 415.6 9.6 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 EGO52715.1 - 5.4e-19 68.0 1.6 4.2e-18 65.2 1.0 2.3 2 0 0 2 2 2 1 Spc7_C2 kleA_kleC PF17383.2 EGO52715.1 - 0.009 16.3 3.3 0.077 13.3 2.9 2.8 2 0 0 2 2 2 1 Uncharacterized KorC regulated protein A PEARLI-4 PF05278.12 EGO52715.1 - 0.27 10.8 10.9 0.013 15.1 3.1 2.8 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Fib_alpha PF08702.10 EGO52715.1 - 1.6 8.9 7.3 41 4.3 3.5 3.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 EGO52715.1 - 5.2 7.8 8.8 7.3 7.3 4.3 3.4 2 1 1 3 3 3 0 SlyX Ribosomal_S17_N PF16205.5 EGO52716.1 - 4.6e-33 113.4 0.3 7.7e-33 112.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EGO52716.1 - 3.1e-27 94.5 0.5 5.8e-27 93.6 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 SWI-SNF_Ssr4 PF08549.10 EGO52717.1 - 1.1e-261 870.6 0.2 1.4e-261 870.3 0.2 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Vir_act_alpha_C PF10400.9 EGO52717.1 - 0.063 14.0 1.1 2 9.2 0.0 2.3 2 0 0 2 2 2 0 Virulence activator alpha C-term 6PGD PF00393.19 EGO52718.1 - 2.4e-128 427.6 0.0 3e-128 427.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGO52718.1 - 8e-52 175.6 0.0 1.4e-51 174.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGO52718.1 - 0.016 15.4 0.0 0.057 13.7 0.0 1.9 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 EGO52718.1 - 0.089 12.1 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGO52718.1 - 0.13 12.8 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RRM_1 PF00076.22 EGO52719.1 - 1.6e-17 63.1 0.1 2.5e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytotoxic PF09000.10 EGO52719.1 - 0.0096 16.2 0.1 0.0096 16.2 0.1 2.3 2 0 0 2 2 2 1 Cytotoxic Glyco_hydro_15 PF00723.21 EGO52720.1 - 1.4e-51 175.7 0.0 6e-47 160.4 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 TPT PF03151.16 EGO52721.1 - 3.6e-18 65.9 17.6 4.6e-18 65.6 17.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGO52721.1 - 1.8e-06 28.2 35.4 0.00011 22.4 6.6 2.5 2 1 0 2 2 2 2 EamA-like transporter family FAM199X PF15814.5 EGO52721.1 - 1.6 7.7 6.4 5.6 5.9 0.5 2.4 2 0 0 2 2 2 0 Protein family FAM199X AF-4 PF05110.13 EGO52721.1 - 7.9 4.4 10.9 14 3.6 10.9 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Bromo_TP PF07524.13 EGO52722.1 - 5.2e-10 39.2 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EGO52722.1 - 0.043 13.9 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TAFII55_N PF04658.13 EGO52723.1 - 6.9e-52 175.4 0.0 1.4e-51 174.4 0.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region CENP-B_dimeris PF09026.10 EGO52723.1 - 0.0044 17.4 7.4 0.0044 17.4 7.4 2.4 3 0 0 3 3 3 1 Centromere protein B dimerisation domain TPD52 PF04201.15 EGO52723.1 - 0.13 11.9 1.7 0.21 11.2 0.7 1.6 1 1 0 1 1 1 0 Tumour protein D52 family FAM176 PF14851.6 EGO52723.1 - 1.1 9.0 4.4 2.9 7.5 4.4 1.7 1 0 0 1 1 1 0 FAM176 family DUF3602 PF12223.8 EGO52723.1 - 1.4 9.5 7.1 0.15 12.7 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) DNA_pol_phi PF04931.13 EGO52723.1 - 2.2 6.2 12.7 4 5.4 12.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi PDDEXK_6 PF04720.12 EGO52723.1 - 2.5 8.0 4.7 5.2 7.0 4.7 1.5 1 0 0 1 1 1 0 PDDEXK-like family of unknown function CDC45 PF02724.14 EGO52723.1 - 5.9 5.0 7.1 9.5 4.4 7.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_60s PF00428.19 EGO52723.1 - 7.6 7.2 14.1 6.7 7.4 10.5 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_L37 PF08561.10 EGO52724.1 - 1.7e-44 151.2 3.5 2.2e-44 150.8 3.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 FXR_C1 PF16096.5 EGO52724.1 - 0.0073 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Fragile X-related 1 protein C-terminal region 2 HWE_HK PF07536.14 EGO52725.1 - 0.095 13.4 0.0 0.17 12.6 0.0 1.4 1 0 0 1 1 1 0 HWE histidine kinase RRM_1 PF00076.22 EGO52726.1 - 5.3e-37 125.5 0.0 6.2e-19 67.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 EGO52726.1 - 0.00088 18.9 0.0 0.7 9.6 0.0 2.4 2 0 0 2 2 2 2 Histone lysine methyltransferase SET associated Apt1 PF10351.9 EGO52726.1 - 0.038 12.9 17.6 0.042 12.7 17.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EGO52726.1 - 0.11 11.1 11.8 0.12 10.9 11.8 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 EGO52726.1 - 0.17 10.6 16.2 0.21 10.3 16.2 1.2 1 0 0 1 1 1 0 Presenilin Mem_trans PF03547.18 EGO52726.1 - 0.5 8.7 3.2 0.45 8.9 3.2 1.1 1 0 0 1 1 1 0 Membrane transport protein TFIIF_alpha PF05793.12 EGO52726.1 - 0.92 8.0 40.9 1.4 7.4 40.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2151 PF10221.9 EGO52726.1 - 2.3 6.7 10.3 2.8 6.4 10.3 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Zip PF02535.22 EGO52726.1 - 3.5 6.8 14.1 4.8 6.3 14.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter KIF1B PF12423.8 EGO52729.1 - 0.3 11.5 1.8 0.62 10.5 1.8 1.6 1 0 0 1 1 1 0 Kinesin protein 1B WH2 PF02205.20 EGO52730.1 - 6e-08 32.3 0.4 6e-08 32.3 0.4 3.1 4 0 0 4 4 4 1 WH2 motif MTA_R1 PF17226.2 EGO52732.1 - 0.16 12.1 0.9 0.48 10.6 0.5 2.0 1 1 1 2 2 2 0 MTA R1 domain Hid1 PF12722.7 EGO52732.1 - 1.7 6.6 4.1 2.6 6.0 4.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cyt_bd_oxida_II PF02322.15 EGO52733.1 - 0.051 12.9 4.0 0.085 12.2 4.0 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DUF4231 PF14015.6 EGO52733.1 - 0.052 14.0 0.2 0.12 12.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF4418 PF14387.6 EGO52733.1 - 0.43 10.8 4.2 5 7.4 4.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4418) UL42 PF17638.2 EGO52733.1 - 6.8 6.7 7.4 7.1 6.6 4.0 2.3 2 0 0 2 2 2 0 HCMV UL42 CHORD PF04968.12 EGO52734.1 - 1.1e-33 115.7 18.6 7.4e-26 90.7 6.9 3.2 2 1 1 3 3 3 3 CHORD CS PF04969.16 EGO52734.1 - 9.3e-16 58.6 0.2 1.5e-15 58.0 0.2 1.3 1 0 0 1 1 1 1 CS domain Pox_F11 PF04943.12 EGO52734.1 - 0.17 10.9 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus F11 protein DUF836 PF05768.14 EGO52735.1 - 4.4e-13 49.4 0.0 5.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 EGO52735.1 - 0.0012 19.0 0.1 0.0038 17.4 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin HpcH_HpaI PF03328.14 EGO52736.1 - 1.6e-32 112.5 0.0 1.8e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.6 EGO52736.1 - 0.039 13.4 0.8 8.9 5.7 0.1 3.1 2 1 1 3 3 3 0 Phosphoenolpyruvate phosphomutase PK PF00224.21 EGO52736.1 - 0.12 11.3 0.0 0.25 10.2 0.0 1.6 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain LSM PF01423.22 EGO52737.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 LSM domain IU_nuc_hydro PF01156.19 EGO52738.1 - 3.6e-57 194.3 0.0 6e-57 193.5 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PVL_ORF50 PF07768.11 EGO52740.1 - 0.0061 16.9 2.7 0.0061 16.9 2.7 2.2 2 0 0 2 2 2 1 PVL ORF-50-like family Rhomboid PF01694.22 EGO52742.1 - 7e-20 71.5 13.5 1.4e-19 70.6 13.5 1.4 1 0 0 1 1 1 1 Rhomboid family PhoD PF09423.10 EGO52743.1 - 0.008 15.2 0.0 0.008 15.2 0.0 2.7 4 0 0 4 4 4 2 PhoD-like phosphatase COX7a PF02238.15 EGO52745.1 - 0.086 13.3 0.0 0.1 13.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII HLH PF00010.26 EGO52746.1 - 7.8e-14 51.4 0.9 1.4e-13 50.5 0.9 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nup_retrotrp_bd PF10599.9 EGO52746.1 - 6.5 7.5 20.4 0.078 13.6 1.5 4.1 4 1 0 4 4 4 0 Retro-transposon transporting motif Aldedh PF00171.22 EGO52747.1 - 1.4e-106 356.8 0.0 1.7e-106 356.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SKG6 PF08693.10 EGO52748.1 - 0.083 12.3 3.4 0.19 11.2 3.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SCIMP PF15050.6 EGO52748.1 - 2.5 8.6 5.7 0.97 9.9 1.8 2.3 2 1 0 2 2 2 0 SCIMP protein CBFD_NFYB_HMF PF00808.23 EGO52749.1 - 1.8e-10 41.0 0.1 2.9e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGO52749.1 - 3.9e-08 33.7 0.0 3.9e-08 33.7 0.0 2.9 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PPP4R2 PF09184.11 EGO52749.1 - 0.0015 18.2 23.3 0.0015 18.2 23.3 1.9 2 0 0 2 2 2 1 PPP4R2 CENP-T_C PF15511.6 EGO52749.1 - 0.0099 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DUF3915 PF13054.6 EGO52749.1 - 0.063 13.3 0.0 0.063 13.3 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3915) Hid1 PF12722.7 EGO52749.1 - 1.3 7.1 9.3 1.9 6.5 9.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLD3 PF08639.10 EGO52750.1 - 5.5e-188 626.1 9.4 5.5e-188 626.1 9.4 2.5 1 1 1 2 2 2 1 DNA replication regulator SLD3 Pkinase PF00069.25 EGO52751.1 - 1.2e-68 231.3 0.0 2.2e-68 230.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO52751.1 - 2.3e-36 125.4 0.0 3.9e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO52751.1 - 9.8e-05 21.8 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGO52751.1 - 0.0015 17.4 0.2 0.0038 16.1 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGO52751.1 - 0.06 13.3 0.1 1.2 9.0 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGO52751.1 - 0.076 11.9 0.0 0.16 10.8 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGO52751.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Homeodomain PF00046.29 EGO52753.1 - 2.2e-14 53.0 1.1 2.2e-14 53.0 1.1 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 EGO52753.1 - 0.00011 22.0 0.4 0.0014 18.5 0.2 2.5 2 0 0 2 2 2 1 Homeobox KN domain HAD_2 PF13419.6 EGO52754.1 - 8.6e-19 68.3 0.0 1.1e-18 68.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGO52754.1 - 2.6e-09 37.7 0.0 0.00017 22.0 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGO52754.1 - 4e-06 27.4 0.0 4.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EGO52754.1 - 0.00015 21.9 0.0 0.064 13.4 0.0 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase GHL6 PF14871.6 EGO52754.1 - 0.051 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 TPR_12 PF13424.6 EGO52755.1 - 6.9e-07 29.5 0.8 2.3e-05 24.6 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO52755.1 - 1e-05 25.2 0.3 0.00042 20.1 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGO52755.1 - 4.9e-05 23.1 0.2 0.011 15.8 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGO52755.1 - 5e-05 22.9 0.0 0.035 13.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGO52755.1 - 0.00018 21.4 0.1 0.0047 17.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGO52755.1 - 0.00042 20.1 0.3 0.0027 17.5 0.1 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGO52755.1 - 0.0011 19.5 0.4 0.0036 17.9 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO52755.1 - 0.021 15.3 1.1 0.077 13.5 0.4 2.1 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO52755.1 - 0.05 14.3 1.8 2 9.2 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGO52755.1 - 0.15 11.8 0.1 11 5.8 0.1 2.6 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 EGO52755.1 - 0.18 12.7 0.4 3.1 8.9 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat GN3L_Grn1 PF08701.11 EGO52756.1 - 4.8e-24 84.3 17.3 8.3e-24 83.5 17.3 1.4 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EGO52756.1 - 2.1e-17 63.2 0.1 3.2e-12 46.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO52756.1 - 9.6e-08 32.1 0.3 1.9e-06 27.9 0.0 2.5 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EGO52756.1 - 1.4e-07 31.7 5.4 0.0027 17.8 0.3 3.4 2 2 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 EGO52756.1 - 6.2e-06 25.9 0.0 0.12 11.9 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGO52756.1 - 0.0007 19.2 0.0 0.011 15.2 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 EGO52756.1 - 0.015 14.3 0.9 0.028 13.4 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PHC2_SAM_assoc PF16616.5 EGO52756.1 - 0.023 15.5 1.2 0.023 15.5 1.2 2.2 1 1 1 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Nuc_deoxyri_tr2 PF15891.5 EGO52756.1 - 0.083 13.2 0.9 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like AAA_18 PF13238.6 EGO52756.1 - 0.09 13.3 0.5 0.26 11.8 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.6 EGO52756.1 - 0.15 12.4 0.1 37 4.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EGO52756.1 - 0.62 10.4 0.0 0.62 10.4 0.0 3.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 EGO52756.1 - 0.81 9.3 3.2 7.8 6.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain CNDH2_C PF16858.5 EGO52756.1 - 1.3 8.8 10.4 2.2 8.1 10.4 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RNB PF00773.19 EGO52757.1 - 8.2e-101 337.6 0.3 1.2e-100 337.0 0.3 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 EGO52757.1 - 9.8e-32 108.8 0.2 3.4e-31 107.0 0.1 2.0 2 0 0 2 2 2 1 S1 domain Rrp44_CSD1 PF17216.3 EGO52757.1 - 3.1e-29 101.6 0.0 8.8e-29 100.1 0.0 1.8 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 EGO52757.1 - 2.6e-20 72.2 0.0 8.2e-20 70.6 0.0 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EGO52757.1 - 4.7e-11 43.1 0.1 1.2e-10 41.7 0.1 1.8 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 EGO52757.1 - 1.2e-08 35.0 0.2 0.00032 20.8 0.0 3.3 3 0 0 3 3 3 2 Cold shock domain Dis3l2_C_term PF17877.1 EGO52757.1 - 0.0065 16.8 0.0 0.022 15.1 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CRC_subunit PF08624.10 EGO52758.1 - 1.5e-52 177.6 0.0 2.1e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Trs65 PF12735.7 EGO52759.1 - 1.3e-135 451.8 0.2 1.7e-135 451.5 0.2 1.1 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 DUF5401 PF17380.2 EGO52759.1 - 1.5 6.8 3.0 2.4 6.1 3.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Med3 PF11593.8 EGO52759.1 - 9.4 5.3 12.1 13 4.8 12.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FF PF01846.19 EGO52760.1 - 4e-53 177.4 10.8 6.5e-14 51.8 0.1 6.8 6 0 0 6 6 6 6 FF domain WW PF00397.26 EGO52760.1 - 2.8e-17 62.5 19.1 7.8e-10 38.7 4.7 2.7 2 0 0 2 2 2 2 WW domain HycH PF07450.11 EGO52760.1 - 0.059 13.8 0.1 0.15 12.5 0.1 1.7 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH Lipin_mid PF16876.5 EGO52760.1 - 0.071 13.3 0.1 3.8 7.7 0.1 2.8 1 1 1 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Glyco_hyd_101C PF17451.2 EGO52760.1 - 1.9 8.8 7.5 17 5.8 2.7 2.8 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Dimer_Tnp_hAT PF05699.14 EGO52761.1 - 3e-06 26.9 0.0 3e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ABC_tran PF00005.27 EGO52762.1 - 2.3e-33 115.6 0.0 9.2e-16 58.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGO52762.1 - 3e-12 47.0 8.2 0.013 15.3 0.1 4.4 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGO52762.1 - 8.1e-10 38.5 1.1 0.0068 15.9 0.1 3.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGO52762.1 - 6.3e-06 26.1 0.0 0.14 11.8 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA PF00004.29 EGO52762.1 - 2.2e-05 24.9 0.1 0.042 14.3 0.1 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO52762.1 - 3.3e-05 24.2 0.0 0.0087 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGO52762.1 - 0.00026 21.4 0.0 0.14 12.6 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EGO52762.1 - 0.00046 20.7 0.1 1.6 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 EGO52762.1 - 0.00048 19.8 2.0 0.032 13.8 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_23 PF13476.6 EGO52762.1 - 0.00065 20.3 0.0 0.19 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGO52762.1 - 0.00065 19.6 0.4 0.77 9.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase Rad17 PF03215.15 EGO52762.1 - 0.00068 19.6 0.0 0.065 13.2 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 EGO52762.1 - 0.00071 19.3 0.1 0.2 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 EGO52762.1 - 0.0016 18.1 0.2 0.95 9.1 0.1 3.0 3 0 0 3 3 3 1 Thymidylate kinase NB-ARC PF00931.22 EGO52762.1 - 0.0017 17.6 0.0 0.091 11.9 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_28 PF13521.6 EGO52762.1 - 0.0019 18.5 0.1 0.35 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGO52762.1 - 0.002 18.5 0.1 1 9.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 EGO52762.1 - 0.0035 17.5 0.0 0.74 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGO52762.1 - 0.004 16.9 1.0 2.1 8.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_13 PF13166.6 EGO52762.1 - 0.004 15.9 0.0 0.004 15.9 0.0 2.0 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EGO52762.1 - 0.0052 16.7 1.0 0.79 9.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_5 PF07728.14 EGO52762.1 - 0.011 15.8 0.2 0.78 9.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGO52762.1 - 0.012 15.1 0.8 0.16 11.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 EGO52762.1 - 0.022 14.8 0.3 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EGO52762.1 - 0.03 14.1 0.4 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGO52762.1 - 0.058 13.8 2.1 19 5.7 0.0 3.9 4 0 0 4 4 4 0 AAA domain MMR_HSR1 PF01926.23 EGO52762.1 - 0.13 12.4 0.7 19 5.4 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 EGO52762.1 - 0.16 11.9 3.4 1.8 8.5 0.1 2.7 3 0 0 3 3 2 0 NTPase CLP1_P PF16575.5 EGO52762.1 - 0.21 11.3 0.8 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MobB PF03205.14 EGO52762.1 - 0.45 10.4 1.3 3 7.7 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.9 EGO52762.1 - 0.57 9.9 0.0 0.57 9.9 0.0 2.8 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation SNF2_N PF00176.23 EGO52763.1 - 1.4e-55 188.4 0.0 2.5e-55 187.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 EGO52763.1 - 1.2e-27 95.5 3.7 2e-16 59.6 0.6 3.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 EGO52763.1 - 8e-20 71.2 0.0 1.9e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 EGO52763.1 - 6.6e-12 45.7 0.0 2.5e-11 43.8 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) ResIII PF04851.15 EGO52763.1 - 4.6e-08 33.3 0.0 2.4e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGO52763.1 - 9e-07 28.3 0.0 4.2e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Cdh1_DBD_1 PF18196.1 EGO52763.1 - 4.1e-06 27.1 0.3 4.1e-06 27.1 0.3 5.0 4 1 1 5 5 4 1 Chromodomain helicase DNA-binding domain 1 SLIDE PF09111.10 EGO52763.1 - 0.017 15.1 0.3 0.36 10.9 0.0 3.0 2 0 0 2 2 2 0 SLIDE POR PF01558.18 EGO52763.1 - 0.023 14.8 0.2 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase AAA_22 PF13401.6 EGO52763.1 - 0.087 13.1 0.0 0.5 10.6 0.0 2.4 2 1 0 2 2 1 0 AAA domain CHDCT2 PF08074.11 EGO52763.1 - 0.11 12.6 2.5 0.23 11.6 0.1 2.9 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain SIR2 PF02146.17 EGO52765.1 - 2.7e-28 99.1 0.0 8.7e-28 97.4 0.0 1.8 1 1 0 1 1 1 1 Sir2 family Med3 PF11593.8 EGO52765.1 - 6.1 5.9 14.5 10 5.2 14.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Med16 PF11635.8 EGO52766.1 - 1.2e-71 241.7 0.0 6.8e-71 239.2 0.0 2.0 1 1 0 1 1 1 1 Mediator complex subunit 16 DUF3500 PF12006.8 EGO52767.1 - 1.4e-109 366.2 0.0 1.7e-109 365.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) CENP-F_leu_zip PF10473.9 EGO52768.1 - 0.0012 18.9 8.7 0.13 12.3 2.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 EGO52768.1 - 0.0067 16.5 8.8 0.054 13.5 0.7 2.5 2 0 0 2 2 2 1 Laminin Domain II Dynactin_p22 PF07426.11 EGO52768.1 - 0.029 14.2 10.1 0.14 12.0 1.5 3.0 1 1 2 3 3 3 0 Dynactin subunit p22 DUF4226 PF10774.9 EGO52768.1 - 0.034 14.4 2.3 0.045 14.0 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) Filament PF00038.21 EGO52768.1 - 0.038 13.6 9.7 1.1 8.8 2.0 2.1 1 1 1 2 2 2 0 Intermediate filament protein Prefoldin_2 PF01920.20 EGO52768.1 - 0.043 13.8 7.2 0.54 10.2 1.6 3.2 3 0 0 3 3 3 0 Prefoldin subunit TSC22 PF01166.18 EGO52768.1 - 0.061 13.6 1.6 14 6.1 0.0 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF2353 PF09789.9 EGO52768.1 - 0.064 12.6 8.1 0.095 12.0 8.1 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Bacillus_HBL PF05791.11 EGO52768.1 - 0.069 13.0 14.2 0.63 9.9 5.3 2.9 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) CDPS PF16715.5 EGO52768.1 - 0.1 12.3 2.7 4.3 6.9 0.2 2.1 2 0 0 2 2 2 0 Cyclodipeptide synthase RE_MjaI PF09568.10 EGO52768.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 MjaI restriction endonuclease DUF2115 PF09888.9 EGO52768.1 - 0.11 13.0 0.3 0.75 10.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DUF4407 PF14362.6 EGO52768.1 - 0.15 11.4 7.6 0.44 9.8 7.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin PF02996.17 EGO52768.1 - 0.15 12.0 6.8 0.26 11.2 0.6 2.9 2 1 1 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.12 EGO52768.1 - 0.18 11.8 9.5 0.12 12.4 2.0 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HIP1_clath_bdg PF16515.5 EGO52768.1 - 0.19 12.4 12.9 2.7 8.7 6.6 2.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ABC_tran_CTD PF16326.5 EGO52768.1 - 0.2 11.9 8.0 3.5 7.9 1.9 3.8 2 2 1 3 3 3 0 ABC transporter C-terminal domain BRE1 PF08647.11 EGO52768.1 - 0.25 11.5 10.2 0.52 10.4 2.1 3.0 1 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase GAS PF13851.6 EGO52768.1 - 0.27 10.6 13.5 0.21 10.9 4.8 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tweety PF04906.13 EGO52768.1 - 0.36 9.4 3.7 0.19 10.4 0.7 1.8 1 1 1 2 2 2 0 Tweety Jnk-SapK_ap_N PF09744.9 EGO52768.1 - 0.42 10.8 11.8 1.5 9.1 0.8 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 EGO52768.1 - 0.43 9.4 11.9 0.49 9.2 0.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein HrpB7 PF09486.10 EGO52768.1 - 0.49 10.8 3.4 8.8 6.7 0.2 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 EGO52768.1 - 0.55 10.3 7.9 7.5 6.6 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 EGO52768.1 - 0.66 10.3 12.5 15 5.9 3.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Sec34 PF04136.15 EGO52768.1 - 0.86 9.5 10.9 0.46 10.4 2.2 2.4 2 1 0 2 2 2 0 Sec34-like family Syntaxin PF00804.25 EGO52768.1 - 0.91 9.2 8.1 0.4 10.3 2.1 2.2 1 1 1 2 2 2 0 Syntaxin CorA PF01544.18 EGO52768.1 - 0.97 8.7 7.0 1.7 7.9 6.8 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein WXG100 PF06013.12 EGO52768.1 - 1 9.6 7.3 4.9 7.5 0.5 3.3 2 1 2 4 4 4 0 Proteins of 100 residues with WXG KxDL PF10241.9 EGO52768.1 - 1.4 9.3 10.6 3.3 8.1 2.1 3.4 2 1 1 3 3 3 0 Uncharacterized conserved protein Cortex-I_coil PF09304.10 EGO52768.1 - 1.6 9.0 8.1 3.9 7.8 2.6 2.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil APG6_N PF17675.1 EGO52768.1 - 1.7 9.1 13.5 8 7.0 8.5 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region TACC_C PF05010.14 EGO52768.1 - 2.6 7.8 8.8 5 6.9 3.1 2.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal She9_MDM33 PF05546.11 EGO52768.1 - 2.7 7.7 7.3 6.7 6.5 0.2 2.3 1 1 0 2 2 2 0 She9 / Mdm33 family DUF3116 PF11313.8 EGO52768.1 - 3.1 7.7 5.5 4.2 7.3 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3116) FapA PF03961.13 EGO52768.1 - 3.2 6.2 8.4 2.1 6.8 2.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A CLZ PF16526.5 EGO52768.1 - 3.4 8.1 9.5 14 6.1 3.5 3.4 2 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc24 PF08286.11 EGO52768.1 - 3.4 8.0 12.0 3.4 8.0 2.2 3.0 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Nup54 PF13874.6 EGO52768.1 - 3.5 7.7 13.1 0.5 10.5 5.4 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DHR10 PF18595.1 EGO52768.1 - 3.5 7.7 12.5 0.27 11.3 3.7 2.6 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Prominin PF05478.11 EGO52768.1 - 4 5.3 9.0 0.67 7.8 3.6 1.8 1 1 1 2 2 2 0 Prominin FlxA PF14282.6 EGO52768.1 - 4.5 7.3 23.3 1.8 8.6 2.3 3.4 3 0 0 3 3 3 0 FlxA-like protein Fib_alpha PF08702.10 EGO52768.1 - 4.8 7.4 10.8 9.3 6.4 1.8 2.6 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4795 PF16043.5 EGO52768.1 - 5.3 6.6 10.2 14 5.2 2.5 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) ZapB PF06005.12 EGO52768.1 - 6.3 7.3 16.8 11 6.5 8.6 3.2 2 2 0 2 2 2 0 Cell division protein ZapB DUF4404 PF14357.6 EGO52768.1 - 6.5 7.5 12.1 3 8.5 3.7 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) YscO PF07321.12 EGO52768.1 - 7.7 6.5 10.5 18 5.3 0.8 2.5 2 1 0 2 2 2 0 Type III secretion protein YscO TMPIT PF07851.13 EGO52768.1 - 8.7 5.5 9.1 10 5.2 1.6 2.2 1 1 1 2 2 2 0 TMPIT-like protein Glyco_transf_34 PF05637.12 EGO52769.1 - 5.8e-65 219.4 0.7 7.6e-65 219.0 0.7 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF3328 PF11807.8 EGO52772.1 - 0.05 13.4 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Peptidase_M22 PF00814.25 EGO52773.1 - 2.1e-49 168.7 1.3 7.9e-26 91.3 0.3 3.4 2 1 0 2 2 2 2 Glycoprotease family FGGY_C PF02782.16 EGO52773.1 - 0.0052 16.5 0.1 0.27 10.9 0.0 2.7 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Proteasome PF00227.26 EGO52774.1 - 5.6e-48 162.9 0.3 6.8e-48 162.7 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF1752 PF08550.10 EGO52776.1 - 4.2e-11 42.5 3.4 8.8e-11 41.4 3.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Met_10 PF02475.16 EGO52778.1 - 7.5e-83 277.2 0.0 1e-82 276.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein DUF1398 PF07166.11 EGO52778.1 - 0.057 13.5 0.0 2.3 8.3 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1398) Sec10 PF07393.11 EGO52780.1 - 7.4e-226 751.9 0.0 9e-226 751.6 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF2336 PF10098.9 EGO52780.1 - 0.017 14.6 0.0 0.44 10.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2336) HLH PF00010.26 EGO52782.1 - 8.4e-16 57.7 0.0 1.8e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tropomyosin PF00261.20 EGO52782.1 - 0.0098 15.3 0.5 0.018 14.4 0.5 1.4 1 0 0 1 1 1 1 Tropomyosin Orf78 PF06024.12 EGO52783.1 - 0.0027 18.0 0.0 0.007 16.7 0.0 1.6 1 0 0 1 1 1 1 Orf78 (ac78) Kelch_3 PF13415.6 EGO52783.1 - 0.0047 17.2 0.1 0.19 12.1 0.0 3.7 2 0 0 2 2 2 1 Galactose oxidase, central domain TMEM154 PF15102.6 EGO52783.1 - 0.86 9.5 9.7 6.1 6.8 9.7 2.2 1 1 0 1 1 1 0 TMEM154 protein family TAP_C PF03943.13 EGO52784.1 - 7.8e-15 54.3 0.4 1.5e-14 53.3 0.4 1.5 1 0 0 1 1 1 1 TAP C-terminal domain RRM_9 PF18444.1 EGO52784.1 - 1.9e-06 27.6 0.0 4.4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif NTF2 PF02136.20 EGO52784.1 - 2e-05 25.1 0.0 0.00023 21.7 0.0 2.5 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.7 EGO52784.1 - 0.00014 22.2 4.3 0.14 12.6 0.7 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGO52784.1 - 0.0023 17.7 3.7 0.0026 17.5 1.6 2.2 2 1 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 EGO52784.1 - 0.0023 17.4 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 EGO52784.1 - 0.027 14.5 4.2 6.1 7.2 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 EGO52784.1 - 0.75 10.6 4.3 36 5.4 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat Helicase_C PF00271.31 EGO52786.1 - 3e-23 82.3 0.0 6.9e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO52786.1 - 1.6e-22 80.3 0.0 3.7e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGO52786.1 - 1e-16 61.2 0.0 3.2e-16 59.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGO52786.1 - 0.00078 19.7 0.0 0.0032 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain SWI2_SNF2 PF18766.1 EGO52786.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase MSC PF09402.10 EGO52787.1 - 3.1e-111 372.1 0.0 4.6e-111 371.5 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EGO52787.1 - 1.5e-17 63.0 0.1 2.7e-17 62.2 0.1 1.4 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.11 EGO52787.1 - 0.00065 19.2 0.1 0.0015 18.1 0.1 1.5 1 0 0 1 1 1 1 Thymopoietin protein Plasmodium_Vir PF05795.11 EGO52787.1 - 1.1 8.6 4.6 2.4 7.5 4.6 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein HisG PF01634.18 EGO52789.1 - 4.6e-55 186.0 0.1 8.4e-55 185.1 0.1 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EGO52789.1 - 3.9e-29 100.6 0.7 1e-28 99.3 0.3 1.9 2 0 0 2 2 2 1 HisG, C-terminal domain KDZ PF18758.1 EGO52789.1 - 0.2 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase MFS_2 PF13347.6 EGO52790.1 - 2e-10 39.8 12.9 2e-10 39.8 12.9 2.5 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 EGO52790.1 - 1.2e-05 24.3 2.3 8.1e-05 21.6 3.2 1.9 2 1 0 2 2 2 1 MFS_1 like family Nuc_H_symport PF03825.16 EGO52790.1 - 0.032 13.2 6.7 0.079 11.9 3.1 2.5 2 0 0 2 2 2 0 Nucleoside H+ symporter Sel1 PF08238.12 EGO52791.1 - 3.5e-41 138.7 27.3 4.9e-06 27.0 0.3 7.5 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 EGO52791.1 - 0.32 11.7 4.0 5.8 7.8 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Chitin_synth_2 PF03142.15 EGO52792.1 - 1.1e-290 964.7 0.1 1.6e-290 964.2 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EGO52792.1 - 7.2e-14 52.2 3.1 3.2e-13 50.0 3.1 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGO52792.1 - 3.1e-10 40.3 0.2 9.2e-09 35.5 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGO52792.1 - 0.00084 18.9 0.1 0.0041 16.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EGO52792.1 - 0.011 15.6 0.0 0.21 11.4 0.0 2.6 3 0 0 3 3 3 0 Glycosyl transferase family 2 Cyt-b5 PF00173.28 EGO52792.1 - 0.013 15.6 0.0 3.7 7.8 0.0 2.8 2 1 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain HemY_N PF07219.13 EGO52792.1 - 3.4 7.9 6.3 0.44 10.8 0.6 2.5 3 0 0 3 3 3 0 HemY protein N-terminus DUF2415 PF10313.9 EGO52793.1 - 0.022 14.7 0.2 0.065 13.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Glyco_hydro_17 PF00332.18 EGO52794.1 - 0.0042 16.7 0.2 0.0084 15.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DUF5049 PF16468.5 EGO52794.1 - 0.099 12.5 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5049) RNB PF00773.19 EGO52796.1 - 6.9e-62 209.7 0.0 1.1e-61 209.0 0.0 1.3 1 0 0 1 1 1 1 RNB domain SUIM_assoc PF16619.5 EGO52797.1 - 0.51 10.4 26.1 0.31 11.1 2.5 3.8 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Myb_DNA-bind_6 PF13921.6 EGO52798.1 - 4.4e-06 26.8 0.1 9.4e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGO52798.1 - 0.02 15.1 0.1 0.035 14.3 0.1 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Spt20 PF12090.8 EGO52798.1 - 0.07 12.7 9.6 0.12 12.0 9.6 1.4 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 EGO52798.1 - 0.57 8.9 3.8 0.63 8.7 3.8 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 EGO52798.1 - 0.98 9.4 3.6 1.2 9.1 3.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Orf78 PF06024.12 EGO52798.1 - 1.3 9.4 4.7 33 4.8 0.0 2.4 2 0 0 2 2 2 0 Orf78 (ac78) FAM60A PF15396.6 EGO52798.1 - 5.7 6.9 7.9 9.3 6.2 7.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF3328 PF11807.8 EGO52799.1 - 0.0034 17.2 0.1 0.0048 16.7 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4059 PF13268.6 EGO52799.1 - 0.048 14.1 2.5 0.39 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) Insulin_TMD PF17870.1 EGO52799.1 - 0.073 13.1 0.6 0.12 12.5 0.1 1.6 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment HemY_N PF07219.13 EGO52799.1 - 0.075 13.2 1.8 0.17 12.1 0.6 1.9 2 0 0 2 2 2 0 HemY protein N-terminus Ribonuc_L-PSP PF01042.21 EGO52800.1 - 1.2e-40 138.3 0.0 1.6e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP PMT PF02366.18 EGO52801.1 - 4.6e-85 285.1 13.7 8.3e-85 284.3 13.7 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EGO52801.1 - 1.9e-69 233.3 6.9 1.9e-69 233.3 6.9 3.0 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGO52801.1 - 6.6e-20 71.7 0.1 3.8e-19 69.3 0.0 1.7 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.6 EGO52801.1 - 0.00036 20.8 14.9 0.0006 20.1 7.4 3.7 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase YqzE PF14038.6 EGO52801.1 - 2.3 8.3 4.8 3.8 7.6 0.1 2.6 2 0 0 2 2 2 0 YqzE-like protein zf-C2H2 PF00096.26 EGO52802.1 - 0.0079 16.6 2.4 0.0079 16.6 2.4 3.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 EGO52802.1 - 0.045 13.5 0.6 0.045 13.5 0.6 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain adh_short_C2 PF13561.6 EGO52803.1 - 1.4e-53 181.9 0.0 1.9e-53 181.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO52803.1 - 4.6e-43 147.0 0.0 5.9e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO52803.1 - 3.8e-11 43.2 0.0 5.2e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 KR domain PALP PF00291.25 EGO52803.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Epimerase PF01370.21 EGO52803.1 - 0.027 14.0 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 EGO52803.1 - 0.047 13.4 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.10 EGO52803.1 - 0.06 12.7 0.0 0.082 12.3 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ABC_tran PF00005.27 EGO52804.1 - 5.8e-50 169.4 0.0 1.8e-17 64.2 0.0 3.4 3 0 0 3 3 3 3 ABC transporter ABC_membrane PF00664.23 EGO52804.1 - 8.7e-31 107.6 14.9 5.5e-25 88.6 12.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGO52804.1 - 1.1e-09 38.0 0.0 0.0021 17.6 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGO52804.1 - 1.3e-05 24.9 1.0 0.17 11.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGO52804.1 - 5.1e-05 23.2 2.4 4.8 6.9 0.8 4.2 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EGO52804.1 - 6.7e-05 22.9 0.8 0.067 13.3 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO52804.1 - 8.1e-05 22.6 0.4 0.34 10.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGO52804.1 - 0.00023 21.4 0.1 4.2 7.6 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 EGO52804.1 - 0.00025 20.7 1.1 0.37 10.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 EGO52804.1 - 0.00031 20.9 3.1 0.056 13.5 0.1 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_23 PF13476.6 EGO52804.1 - 0.00079 20.0 0.1 0.23 11.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGO52804.1 - 0.0011 19.3 1.8 0.33 11.3 0.1 3.4 4 0 0 4 4 3 1 AAA ATPase domain Zeta_toxin PF06414.12 EGO52804.1 - 0.0013 18.0 0.2 0.46 9.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 EGO52804.1 - 0.0086 16.0 0.7 2.1 8.3 0.3 2.6 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 EGO52804.1 - 0.012 14.8 0.5 1.6 7.8 0.1 3.0 3 0 0 3 3 3 0 NB-ARC domain MeaB PF03308.16 EGO52804.1 - 0.019 14.0 0.4 0.036 13.0 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EGO52804.1 - 0.031 14.0 0.3 9.8 5.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 EGO52804.1 - 0.039 14.0 0.2 13 5.8 0.0 3.1 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 EGO52804.1 - 0.068 13.7 2.9 6 7.4 0.0 3.7 4 0 0 4 4 3 0 AAA domain DUF2075 PF09848.9 EGO52804.1 - 0.11 11.8 0.6 2.2 7.4 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 EGO52804.1 - 0.11 12.8 0.0 15 6.0 0.0 2.9 3 0 0 3 3 2 0 RNA helicase T2SSE PF00437.20 EGO52804.1 - 0.12 11.4 0.4 0.36 9.9 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.6 EGO52804.1 - 0.15 12.3 0.7 4.4 7.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 EGO52804.1 - 0.19 11.4 0.2 9.7 5.9 0.0 2.9 4 0 0 4 4 3 0 Sigma-54 interaction domain AAA_15 PF13175.6 EGO52804.1 - 0.31 10.7 0.0 16 5.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.15 EGO52804.1 - 0.38 10.6 1.3 7.6 6.4 0.0 3.2 4 0 0 4 4 3 0 NTPase Pro_isomerase PF00160.21 EGO52805.1 - 1e-51 175.3 0.1 2.2e-51 174.3 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EGO52805.1 - 1.2e-11 44.9 0.0 0.00023 21.9 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO52805.1 - 5.2e-05 23.5 0.0 0.14 12.5 0.0 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO52805.1 - 0.075 12.0 0.7 0.98 8.3 0.1 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Far-17a_AIG1 PF04750.14 EGO52806.1 - 4.9e-48 163.1 14.3 5.6e-48 162.9 14.3 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF2374 PF09574.10 EGO52806.1 - 0.14 12.0 2.9 9.1 6.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (Duf2374) DAHP_synth_1 PF00793.20 EGO52808.1 - 9.1e-102 339.6 0.0 1.2e-101 339.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Cytochrom_C1 PF02167.15 EGO52809.1 - 2.3e-93 311.9 0.0 2.9e-93 311.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EGO52809.1 - 0.0064 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EGO52809.1 - 0.058 14.5 0.0 0.31 12.2 0.0 2.2 3 0 0 3 3 3 0 Cytochrome c HhH-GPD PF00730.25 EGO52810.1 - 6.8e-08 32.9 0.0 1.3e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein CVNH PF08881.10 EGO52811.1 - 2.8e-10 40.8 0.6 3.9e-10 40.3 0.6 1.2 1 0 0 1 1 1 1 CVNH domain Nup84_Nup100 PF04121.13 EGO52812.1 - 1.3e-197 658.3 0.0 1.5e-197 658.1 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 TAF1_subA PF14929.6 EGO52812.1 - 0.072 12.5 0.6 0.13 11.6 0.6 1.3 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A MTCP1 PF08991.10 EGO52813.1 - 8.4e-30 102.8 8.2 1e-29 102.6 8.2 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 EGO52813.1 - 0.00038 20.5 6.2 0.00069 19.7 6.2 1.5 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 EGO52813.1 - 0.56 10.3 7.0 0.14 12.2 1.9 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Rad60-SLD PF11976.8 EGO52814.1 - 7.2e-18 64.2 0.1 8.5e-18 64.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGO52814.1 - 1.2e-09 37.7 0.1 1.4e-09 37.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family HH_signal PF01085.18 EGO52814.1 - 0.03 14.0 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain SH3_9 PF14604.6 EGO52814.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Variant SH3 domain LIM PF00412.22 EGO52816.1 - 2.6e-26 91.6 19.6 1.9e-08 34.4 5.7 3.5 3 0 0 3 3 3 3 LIM domain EPL1 PF10513.9 EGO52816.1 - 0.01 16.2 7.8 0.01 16.2 7.8 2.7 3 0 0 3 3 3 0 Enhancer of polycomb-like DUF2321 PF10083.9 EGO52816.1 - 0.027 14.1 0.2 0.027 14.1 0.2 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) Peptidase_S64 PF08192.11 EGO52816.1 - 0.79 8.1 6.8 1.4 7.3 6.8 1.3 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 EGO52816.1 - 0.83 6.7 16.9 1.3 6.1 16.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SpoIIP PF07454.11 EGO52816.1 - 0.98 8.8 14.1 1.7 8.0 14.1 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) eIF-3_zeta PF05091.12 EGO52816.1 - 1.7 7.6 20.0 2.6 6.9 20.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 EGO52816.1 - 1.7 7.3 18.3 3.9 6.1 18.3 1.5 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 EGO52816.1 - 1.8 7.3 11.9 2.9 6.6 11.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 EOS1 PF12326.8 EGO52816.1 - 1.9 8.4 3.5 3.3 7.6 3.5 1.4 1 0 0 1 1 1 0 N-glycosylation protein RR_TM4-6 PF06459.12 EGO52816.1 - 2.1 8.1 16.0 4.2 7.1 16.0 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 EGO52816.1 - 2.5 8.0 8.8 6.7 6.7 8.8 1.8 1 0 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.14 EGO52816.1 - 2.7 6.2 10.7 4 5.6 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 EGO52816.1 - 3.2 6.7 11.6 5.4 5.9 11.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Plasmodium_Vir PF05795.11 EGO52816.1 - 4.7 6.5 6.5 11 5.3 6.5 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CPSF100_C PF13299.6 EGO52816.1 - 5.9 7.0 12.1 13 5.9 12.1 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Hid1 PF12722.7 EGO52816.1 - 8.7 4.3 14.4 17 3.4 14.4 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MFS_1 PF07690.16 EGO52817.1 - 6.5e-22 77.9 54.2 6.5e-22 77.9 54.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Ligase_CoA PF00549.19 EGO52818.1 - 1.1e-34 119.5 1.8 1.5e-19 70.3 0.4 2.3 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 EGO52818.1 - 1.4e-16 60.9 1.3 3.8e-16 59.5 0.1 2.4 3 0 0 3 3 3 1 CoA binding domain Succ_CoA_lig PF13607.6 EGO52818.1 - 1.5e-05 24.8 0.0 0.0032 17.3 0.0 2.6 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CHCH PF06747.13 EGO52819.1 - 0.00087 19.4 0.1 0.0016 18.5 0.1 1.4 1 1 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 EGO52819.1 - 0.011 16.0 2.6 0.15 12.4 2.9 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 EGO52819.1 - 0.029 14.7 3.0 3.6 8.0 0.2 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.16 EGO52819.1 - 0.08 13.2 2.1 0.35 11.1 2.1 1.9 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.12 EGO52819.1 - 0.32 11.3 1.7 17 5.7 0.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Dynamin_M PF01031.20 EGO52821.1 - 1.8e-111 372.0 0.0 3.5e-111 371.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EGO52821.1 - 3e-56 190.1 0.5 5.6e-56 189.2 0.0 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 EGO52821.1 - 1.7e-30 105.0 2.7 1.7e-30 105.0 2.7 1.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGO52821.1 - 6e-05 23.1 0.4 0.0007 19.7 0.4 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase F-box PF00646.33 EGO52822.1 - 2.3e-05 24.1 0.4 5.5e-05 22.9 0.4 1.5 1 0 0 1 1 1 1 F-box domain Hrs_helical PF12210.8 EGO52822.1 - 0.23 12.0 2.4 0.49 11.0 1.5 2.0 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate zinc_ribbon_10 PF10058.9 EGO52822.1 - 0.24 11.2 1.3 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein TPR_MLP1_2 PF07926.12 EGO52822.1 - 1.8 8.6 7.5 0.4 10.7 2.5 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Alpha-amylase PF00128.24 EGO52824.1 - 1.4e-47 163.0 0.3 7.4e-44 150.7 0.3 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.19 EGO52824.1 - 5.9e-22 77.4 0.2 1.3e-21 76.3 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.11 EGO52824.1 - 7.7e-10 38.9 0.1 1.9e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Fungal_trans PF04082.18 EGO52825.1 - 2.1e-14 53.2 0.2 3.8e-14 52.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glutaredoxin PF00462.24 EGO52826.1 - 1.3e-18 66.9 0.0 6e-17 61.6 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EGO52826.1 - 2.3e-13 50.0 0.0 4.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGO52826.1 - 0.0048 17.2 0.0 2.3 8.6 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like TraF PF13728.6 EGO52826.1 - 0.018 14.9 0.0 0.61 9.9 0.0 2.2 1 1 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 EGO52826.1 - 0.042 14.3 0.1 0.4 11.2 0.0 2.6 1 1 1 2 2 2 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EGO52826.1 - 0.052 13.6 0.0 0.37 10.9 0.0 2.3 2 1 0 2 2 2 0 Thioredoxin domain HyaE PF07449.11 EGO52826.1 - 0.12 12.3 0.1 0.89 9.5 0.0 2.3 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE SH3_9 PF14604.6 EGO52829.1 - 9.5e-29 99.0 3.9 9.4e-14 51.0 0.3 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EGO52829.1 - 1.9e-25 88.2 3.8 2.7e-12 46.1 0.4 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EGO52829.1 - 1.8e-16 59.5 0.0 2.4e-07 30.3 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 EGO52829.1 - 3.1e-15 56.0 0.0 6.5e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Mod_r PF07200.13 EGO52831.1 - 3.8e-34 117.9 3.5 4.6e-34 117.6 3.5 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein PE PF00934.20 EGO52831.1 - 0.21 11.9 2.3 0.41 11.0 2.3 1.4 1 0 0 1 1 1 0 PE family F-box PF00646.33 EGO52832.1 - 1.7e-05 24.6 0.2 4.8e-05 23.1 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGO52832.1 - 0.0045 16.9 2.3 0.01 15.7 0.3 2.8 3 0 0 3 3 3 1 F-box-like V-ATPase_C PF03223.15 EGO52834.1 - 8.1e-121 403.9 0.1 9.4e-121 403.7 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Cauli_AT PF03233.13 EGO52834.1 - 0.094 12.6 0.7 0.17 11.8 0.7 1.4 1 0 0 1 1 1 0 Aphid transmission protein DBP10CT PF08147.12 EGO52834.1 - 0.41 10.9 4.0 0.19 12.0 1.1 1.9 2 0 0 2 2 2 0 DBP10CT (NUC160) domain APS_kinase PF01583.20 EGO52835.1 - 9.5e-71 236.8 0.0 1.2e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EGO52835.1 - 1.7e-05 25.0 0.0 3.5e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO52835.1 - 8.2e-05 23.2 0.0 0.00014 22.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EGO52835.1 - 0.0017 17.8 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 EGO52835.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGO52835.1 - 0.13 12.7 0.1 0.23 11.8 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain DUF463 PF04317.12 EGO52835.1 - 0.15 11.0 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 4HBT PF03061.22 EGO52836.1 - 1.1e-09 38.5 0.0 1.8e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily CBF PF03914.17 EGO52837.1 - 1.5e-54 184.6 1.0 1.5e-54 184.6 1.0 3.0 3 1 0 3 3 3 1 CBF/Mak21 family HOASN PF14515.6 EGO52837.1 - 0.13 12.7 0.3 0.51 10.8 0.3 2.0 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices tRNA-synt_2b PF00587.25 EGO52838.1 - 1.2e-32 113.3 0.0 6.7e-32 110.9 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGO52838.1 - 1.3e-06 28.4 0.0 3.8e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain RVT_1 PF00078.27 EGO52839.1 - 0.0018 17.9 0.2 0.0018 17.9 0.2 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3453 PF11935.8 EGO52839.1 - 0.051 13.2 0.1 0.054 13.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) DUF3232 PF11554.8 EGO52839.1 - 0.12 12.8 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) DUF5438 PF17506.2 EGO52848.1 - 0.0032 17.7 2.5 0.0042 17.4 2.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5438) UCH PF00443.29 EGO52850.1 - 1.2e-32 113.4 0.0 4.7e-28 98.4 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO52850.1 - 0.00018 21.2 3.2 0.35 10.4 1.7 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Oxysterol_BP PF01237.18 EGO52852.1 - 4.1e-61 206.9 0.4 7.6e-59 199.4 0.4 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF1627 PF07789.12 EGO52852.1 - 0.13 11.9 0.0 7.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1627) GFO_IDH_MocA PF01408.22 EGO52853.1 - 1.4e-13 51.7 0.0 3.2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGO52853.1 - 5.5e-06 26.4 0.0 1.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Ilar_coat PF01787.16 EGO52853.1 - 0.07 12.9 0.1 0.54 10.0 0.1 2.0 2 0 0 2 2 2 0 Ilarvirus coat protein ImpA_N PF06812.12 EGO52853.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system PGM_PMM_I PF02878.16 EGO52854.1 - 1.4e-33 115.5 0.0 2e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EGO52854.1 - 2.3e-26 92.2 0.0 5.5e-26 91.0 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGO52854.1 - 7.5e-16 58.6 0.0 1.6e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EGO52854.1 - 2.7e-06 27.4 0.0 6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pec_lyase PF09492.10 EGO52856.1 - 0.0055 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Pectic acid lyase HMG_box PF00505.19 EGO52857.1 - 1.8e-25 89.1 1.0 2.9e-25 88.5 1.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO52857.1 - 6.9e-18 65.0 2.7 8.1e-18 64.8 2.1 1.5 1 1 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 EGO52857.1 - 0.0028 18.2 0.0 0.0028 18.2 0.0 2.1 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 EGO52857.1 - 0.012 15.5 0.6 0.024 14.6 0.6 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 CHDNT PF08073.12 EGO52857.1 - 0.04 13.9 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain CENP-H PF05837.12 EGO52858.1 - 4.2e-30 104.4 0.5 6.1e-30 103.9 0.5 1.2 1 0 0 1 1 1 1 Centromere protein H (CENP-H) TMCO5 PF14992.6 EGO52858.1 - 0.12 11.9 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 TMCO5 family ATG11 PF10377.9 EGO52859.1 - 1.3e-46 157.8 0.2 1.3e-46 157.8 0.2 3.3 3 0 0 3 3 3 1 Autophagy-related protein 11 Spectrin PF00435.21 EGO52859.1 - 0.0014 19.1 4.3 0.0014 19.1 4.3 6.8 7 0 0 7 7 7 1 Spectrin repeat ERM PF00769.19 EGO52859.1 - 0.0053 16.6 17.6 0.0053 16.6 17.6 6.2 4 2 2 6 6 6 1 Ezrin/radixin/moesin family FERM_f0 PF16511.5 EGO52859.1 - 0.025 14.9 0.2 1.8 8.9 0.0 2.6 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM Alfin PF12165.8 EGO52859.1 - 0.045 13.4 0.2 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 Alfin MAD PF05557.13 EGO52859.1 - 0.25 9.7 57.6 0.051 11.9 41.0 3.0 2 1 1 3 3 3 0 Mitotic checkpoint protein FPP PF05911.11 EGO52859.1 - 0.34 9.1 47.6 0.06 11.5 12.2 3.3 3 1 0 3 3 3 0 Filament-like plant protein, long coiled-coil NuA4 PF09340.10 EGO52859.1 - 0.65 9.9 7.6 4.9 7.1 0.0 4.1 4 0 0 4 4 4 0 Histone acetyltransferase subunit NuA4 MHCassoc_trimer PF08831.10 EGO52859.1 - 0.88 9.6 3.5 6.4 6.9 0.3 2.8 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Flagellin_C PF00700.21 EGO52859.1 - 1.2 9.6 5.3 1.2 9.5 1.8 3.0 3 0 0 3 3 2 0 Bacterial flagellin C-terminal helical region Lectin_N PF03954.14 EGO52859.1 - 1.6 8.5 19.9 6.6 6.5 2.2 5.1 5 0 0 5 5 5 0 Hepatic lectin, N-terminal domain T3SS_basalb_I PF17001.5 EGO52859.1 - 3.2 8.4 10.8 28 5.4 0.5 4.6 3 0 0 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI Filament PF00038.21 EGO52859.1 - 7.6 6.0 61.8 6.1 6.3 18.1 5.4 3 1 1 4 4 4 0 Intermediate filament protein HU-CCDC81_bac_2 PF18175.1 EGO52859.1 - 8.5 6.3 17.7 1.4 8.9 0.0 5.6 6 1 1 7 7 7 0 CCDC81-like prokaryotic HU domain 2 Ribosomal_L9_N PF01281.19 EGO52860.1 - 1e-11 44.2 0.0 1.7e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 EGO52860.1 - 0.017 15.6 0.0 0.038 14.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L9, C-terminal domain AATase PF07247.12 EGO52861.1 - 2.2e-16 59.5 0.0 3.3e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase LSM PF01423.22 EGO52864.1 - 2.2e-20 72.1 0.1 2.4e-20 72.0 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGO52864.1 - 0.00018 21.6 0.1 0.00021 21.4 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EGO52864.1 - 0.0008 19.5 0.1 0.00094 19.2 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain Hfq PF17209.3 EGO52864.1 - 0.1 12.3 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Hfq protein HSP20 PF00011.21 EGO52865.1 - 1.6e-18 66.7 0.0 3.4e-13 49.6 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGO52865.1 - 1e-05 25.0 0.0 0.00012 21.6 0.0 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA PEP-utilizers PF00391.23 EGO52865.1 - 0.031 14.0 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain YTH PF04146.15 EGO52866.1 - 1.7e-61 207.0 0.0 2.5e-61 206.5 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain Proteasome PF00227.26 EGO52867.1 - 3.4e-31 108.2 0.3 1.8e-30 105.8 0.3 2.1 1 1 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.27 EGO52868.1 - 2.6e-38 132.3 0.1 5e-36 124.8 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGO52868.1 - 2.1e-23 82.7 0.0 5e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Cation_efflux PF01545.21 EGO52869.1 - 2.4e-24 86.2 10.7 3e-24 85.9 10.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGO52869.1 - 2.7e-07 30.6 0.1 5.1e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DMRL_synthase PF00885.19 EGO52871.1 - 1.3e-57 193.5 0.0 1.7e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase HATPase_c_3 PF13589.6 EGO52873.1 - 1.2e-13 51.1 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGO52873.1 - 2.8e-06 27.8 0.0 6.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 EGO52873.1 - 1.8e-05 24.4 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain TRP PF06011.12 EGO52874.1 - 3.7e-38 131.4 17.9 4.7e-37 127.7 17.9 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EGO52874.1 - 8.6e-24 84.5 0.0 8.6e-24 84.5 0.0 1.7 2 0 0 2 2 2 1 ML-like domain WD40 PF00400.32 EGO52875.1 - 1.1e-10 41.8 2.7 0.1 13.5 0.3 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF4213 PF13938.6 EGO52875.1 - 0.17 12.2 0.0 2 8.7 0.0 2.2 2 0 0 2 2 2 0 Putative heavy-metal chelation RNA_pol_Rpb4 PF03874.16 EGO52876.1 - 1.8e-26 92.9 3.3 1.8e-26 92.9 3.3 2.1 2 1 0 2 2 2 1 RNA polymerase Rpb4 Rax2 PF12768.7 EGO52877.1 - 0.04 13.4 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF4514 PF14986.6 EGO52877.1 - 0.22 11.5 0.2 0.4 10.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) CPL PF08144.11 EGO52878.1 - 4.4e-41 140.6 2.0 2e-39 135.2 0.0 3.8 4 0 0 4 4 4 1 CPL (NUC119) domain ASD2 PF08687.11 EGO52878.1 - 8.4 5.9 20.4 0.044 13.4 9.1 2.5 3 0 0 3 3 3 0 Apx/Shroom domain ASD2 RWD PF05773.22 EGO52879.1 - 1.9e-25 89.4 0.6 3.4e-25 88.6 0.6 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 EGO52879.1 - 7.7e-06 26.3 6.3 1.5e-05 25.4 6.3 1.5 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 TPR_19 PF14559.6 EGO52880.1 - 7.4e-08 32.8 2.1 0.0024 18.4 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGO52880.1 - 8.5e-07 29.2 7.7 0.011 16.0 0.6 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO52880.1 - 9.8e-07 28.5 0.0 0.0072 16.4 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO52880.1 - 0.00041 20.2 0.1 0.057 13.5 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGO52880.1 - 0.00089 19.0 0.0 0.012 15.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGO52880.1 - 0.00093 19.1 7.8 0.45 10.7 0.0 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGO52880.1 - 0.0011 19.6 4.8 3.2 8.8 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGO52880.1 - 0.0012 19.5 4.9 0.14 12.8 0.6 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGO52880.1 - 0.021 15.0 3.5 6.6 7.0 0.4 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGO52880.1 - 0.14 12.9 3.3 0.97 10.3 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGO52880.1 - 0.27 11.2 3.4 14 5.7 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO52880.1 - 6.7 7.6 9.8 85 4.1 0.0 5.4 7 0 0 7 7 6 0 Tetratricopeptide repeat CFEM PF05730.11 EGO52881.1 - 0.023 14.8 5.2 0.038 14.1 5.2 1.4 1 0 0 1 1 1 0 CFEM domain Cyclotide PF03784.13 EGO52881.1 - 7 6.8 12.1 0.13 12.4 5.3 1.6 2 0 0 2 2 2 0 Cyclotide family MutS_V PF00488.21 EGO52882.1 - 3.2e-45 154.5 0.1 4.5e-45 154.0 0.1 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGO52882.1 - 0.028 14.7 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 MutS domain III MMgT PF10270.9 EGO52884.1 - 8.5e-36 122.3 0.0 1e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter HMG_box PF00505.19 EGO52885.1 - 6e-09 36.2 1.0 1.5e-08 35.0 1.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO52885.1 - 0.0071 16.9 0.6 0.015 15.9 0.6 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 EGO52885.1 - 0.046 13.0 0.0 0.099 11.9 0.0 1.5 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box EGF PF00008.27 EGO52886.1 - 0.14 12.5 3.1 11 6.5 0.6 2.3 2 0 0 2 2 2 0 EGF-like domain PHD PF00628.29 EGO52887.1 - 1.5e-08 34.4 9.2 3.1e-08 33.4 9.2 1.6 1 0 0 1 1 1 1 PHD-finger PHF5 PF03660.14 EGO52887.1 - 0.049 13.8 2.5 0.092 13.0 2.5 1.3 1 0 0 1 1 1 0 PHF5-like protein PHD_2 PF13831.6 EGO52887.1 - 0.09 12.4 5.3 0.18 11.4 5.3 1.5 1 0 0 1 1 1 0 PHD-finger Ion_trans PF00520.31 EGO52888.1 - 1.9e-112 374.5 69.3 1e-33 116.6 12.9 5.2 5 0 0 5 5 5 5 Ion transport protein EF-hand_1 PF00036.32 EGO52888.1 - 0.12 12.0 0.0 0.37 10.4 0.0 1.9 1 0 0 1 1 1 0 EF hand IMUP PF15761.5 EGO52889.1 - 0.2 12.4 5.8 0.3 11.8 5.8 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Cyclin_N PF00134.23 EGO52892.1 - 2.5e-45 153.3 0.0 1e-44 151.4 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGO52892.1 - 1.8e-34 118.4 0.0 3.5e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain HEPN_Toprim_N PF18871.1 EGO52892.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 Ribosomal_L2_C PF03947.18 EGO52893.1 - 6.8e-51 171.7 1.5 6.8e-51 171.7 1.5 2.2 3 0 0 3 3 3 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGO52893.1 - 3.6e-26 90.9 1.0 6.2e-26 90.2 0.4 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain PAP2 PF01569.21 EGO52894.1 - 2.2e-21 76.1 4.9 2.2e-21 76.1 4.9 2.7 2 1 0 2 2 2 1 PAP2 superfamily DUF1282 PF06930.12 EGO52894.1 - 1.5 8.6 7.5 0.083 12.7 1.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1282) CK_II_beta PF01214.18 EGO52895.1 - 4e-78 261.4 0.6 6.1e-78 260.8 0.6 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RNA_pol_3_Rpc31 PF11705.8 EGO52895.1 - 0.0041 17.4 2.6 0.0057 16.9 2.6 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Myc_N PF01056.18 EGO52895.1 - 0.021 14.7 0.3 0.027 14.4 0.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PTPRCAP PF15713.5 EGO52895.1 - 0.032 14.5 7.7 0.047 14.0 7.7 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 EGO52895.1 - 0.066 11.5 1.8 0.082 11.2 1.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1660 PF07874.11 EGO52895.1 - 0.091 13.3 0.0 20 5.8 0.0 2.8 2 0 0 2 2 2 0 Prophage protein (DUF1660) DUF4746 PF15928.5 EGO52895.1 - 0.11 11.9 3.4 0.2 11.0 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TAF4 PF05236.14 EGO52895.1 - 0.29 10.8 5.5 0.42 10.3 5.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family MRNIP PF15749.5 EGO52895.1 - 0.86 10.4 3.6 1.7 9.4 3.6 1.5 1 0 0 1 1 1 0 MRN-interacting protein Sporozoite_P67 PF05642.11 EGO52895.1 - 1.9 6.5 3.7 2.4 6.1 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 EGO52895.1 - 2.3 6.3 9.3 1.6 6.8 7.9 1.4 2 0 0 2 2 2 0 Nop14-like family NOA36 PF06524.12 EGO52895.1 - 3 7.1 10.1 5.3 6.3 10.1 1.4 1 0 0 1 1 1 0 NOA36 protein DUF4637 PF15470.6 EGO52895.1 - 5.5 6.7 10.8 10 5.8 9.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Paf1 PF03985.13 EGO52895.1 - 6.3 5.7 10.2 8.8 5.2 10.2 1.1 1 0 0 1 1 1 0 Paf1 RIC1 PF07064.13 EGO52896.1 - 8.5e-98 326.8 0.0 1.1e-97 326.3 0.0 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.32 EGO52896.1 - 0.0064 17.3 1.2 40 5.3 0.0 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat WD40 PF00400.32 EGO52897.1 - 3.6e-21 75.1 8.7 0.00034 21.4 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO52897.1 - 1.4e-15 57.3 0.1 0.0058 16.9 0.1 5.7 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGO52897.1 - 2.3e-06 27.6 0.1 0.1 12.5 0.1 3.3 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGO52897.1 - 0.00038 19.2 0.4 0.0028 16.4 0.1 2.0 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EGO52897.1 - 0.0012 17.4 0.0 0.97 7.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 EGO52897.1 - 0.0019 17.2 0.0 0.0038 16.2 0.0 1.5 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain DUF1513 PF07433.11 EGO52897.1 - 0.0082 15.3 0.2 1.4 7.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1513) IKI3 PF04762.12 EGO52897.1 - 0.17 9.9 0.0 1 7.2 0.0 2.0 1 1 1 2 2 2 0 IKI3 family Fungal_trans PF04082.18 EGO52898.1 - 2.3e-20 72.8 0.3 3.6e-20 72.1 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO52898.1 - 6.9e-09 35.7 12.5 7.6e-09 35.6 11.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pilosulin PF17499.2 EGO52899.1 - 2.1 8.5 3.8 4.1 7.6 3.8 1.5 1 1 0 1 1 1 0 Ant venom peptides Pkinase PF00069.25 EGO52900.1 - 4.8e-63 213.0 0.0 1.1e-62 211.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO52900.1 - 1e-28 100.4 0.0 2.5e-28 99.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EGO52900.1 - 9.3e-11 41.9 0.0 5.1e-08 33.2 0.0 3.1 3 0 0 3 3 3 1 FHA domain Kinase-like PF14531.6 EGO52900.1 - 0.0011 18.4 0.0 0.0045 16.3 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Yop-YscD_cpl PF16697.5 EGO52900.1 - 0.02 15.2 0.0 0.051 13.9 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 EGO52900.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.29 EGO52901.1 - 0.0086 16.6 2.5 0.018 15.6 0.0 2.7 3 1 0 3 3 3 1 PH domain SpoIIE PF07228.12 EGO52902.1 - 0.00011 22.1 0.0 0.0011 18.9 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Fcf1 PF04900.12 EGO52903.1 - 8.8e-28 96.6 0.1 1.5e-27 95.9 0.1 1.4 1 0 0 1 1 1 1 Fcf1 Menin PF05053.13 EGO52903.1 - 2.5 6.4 11.4 3.3 5.9 11.4 1.1 1 0 0 1 1 1 0 Menin LAP1C PF05609.12 EGO52903.1 - 4.2 6.4 12.1 5.4 6.0 12.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Neur_chan_memb PF02932.16 EGO52903.1 - 5.1 7.1 6.0 8 6.4 6.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.15 EGO52903.1 - 5.3 5.7 11.4 7.4 5.2 11.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF726 PF05277.12 EGO52904.1 - 6e-97 324.6 14.1 3e-72 243.4 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF726) DUF3439 PF11921.8 EGO52904.1 - 0.054 13.5 6.9 0.15 12.1 6.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 EGO52904.1 - 9 4.1 10.6 15 3.4 10.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Acylphosphatase PF00708.18 EGO52905.1 - 1.9e-25 89.0 0.2 2.1e-25 88.9 0.2 1.0 1 0 0 1 1 1 1 Acylphosphatase DUF2871 PF11070.8 EGO52905.1 - 0.22 11.8 0.1 0.32 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2871) V-ATPase_H_N PF03224.14 EGO52906.1 - 2.4e-82 276.7 0.0 3.7e-82 276.1 0.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EGO52906.1 - 9.3e-36 122.5 0.0 4.1e-35 120.4 0.0 2.2 2 0 0 2 2 2 1 V-ATPase subunit H Sporozoite_P67 PF05642.11 EGO52907.1 - 1.5 6.8 15.2 2.2 6.2 15.0 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Glycophorin_A PF01102.18 EGO52907.1 - 1.7 8.9 4.9 0.25 11.6 0.4 1.9 2 0 0 2 2 2 0 Glycophorin A Phage_holin_3_6 PF07332.11 EGO52907.1 - 4.8 7.2 6.7 12 6.0 4.5 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Ribosomal_L6 PF00347.23 EGO52908.1 - 2.4e-25 89.0 11.5 2.3e-12 47.4 4.5 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Vps26 PF03643.15 EGO52909.1 - 4.8e-131 435.8 0.8 5.5e-131 435.6 0.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EGO52909.1 - 0.00029 20.9 0.4 0.53 10.3 0.0 3.4 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EGO52909.1 - 0.01 16.3 0.0 0.081 13.4 0.0 2.3 1 1 1 2 2 2 0 Arrestin (or S-antigen), C-terminal domain IL17R_D_N PF16742.5 EGO52909.1 - 0.094 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Nup160 PF11715.8 EGO52910.1 - 6.6e-157 523.4 0.1 6.7e-96 322.0 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Rad51 PF08423.11 EGO52911.1 - 1.3e-24 86.9 0.0 1.4e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Rad51 DUF4950 PF16308.5 EGO52911.1 - 0.094 12.7 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4950) DUF3169 PF11368.8 EGO52912.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) GspL_C PF12693.7 EGO52912.1 - 0.23 11.3 0.7 0.42 10.4 0.7 1.5 1 0 0 1 1 1 0 GspL periplasmic domain zf-RING_5 PF14634.6 EGO52913.1 - 5.7 7.0 10.7 22 5.1 10.7 2.1 1 1 0 1 1 1 0 zinc-RING finger domain SH PF01445.17 EGO52914.1 - 0.086 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Viral small hydrophobic protein EF-hand_1 PF00036.32 EGO52915.1 - 2.7e-27 92.2 9.4 1.3e-06 27.5 0.1 5.4 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 EGO52915.1 - 3.9e-22 76.2 8.6 0.00057 19.6 0.2 5.3 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 EGO52915.1 - 5.7e-22 77.9 6.9 1.6e-09 38.1 0.0 3.9 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EGO52915.1 - 4.1e-19 68.2 12.1 2.9e-09 36.6 0.0 5.1 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 EGO52915.1 - 3.1e-16 58.0 8.5 0.00012 21.5 0.4 5.1 5 0 0 5 5 5 4 EF hand ChaC PF04752.12 EGO52916.1 - 5.7e-56 189.4 0.0 7.6e-56 189.0 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein RRM_1 PF00076.22 EGO52917.1 - 3.4e-20 71.6 0.0 4.1e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HpcH_HpaI PF03328.14 EGO52919.1 - 2.7e-43 147.6 0.1 6.8e-43 146.4 0.0 1.6 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EGO52919.1 - 2.2e-14 53.4 0.1 9.5e-07 28.3 0.0 2.0 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF846 PF05832.12 EGO52920.1 - 2.2e-51 173.6 7.9 2.6e-51 173.3 7.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF5504 PF17608.2 EGO52920.1 - 0.057 13.5 0.5 0.057 13.5 0.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5504) DUF4191 PF13829.6 EGO52920.1 - 0.16 11.2 2.8 1.6 8.0 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) SUIM_assoc PF16619.5 EGO52921.1 - 0.011 15.7 0.2 0.011 15.7 0.2 2.8 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Rax2 PF12768.7 EGO52921.1 - 0.03 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Podoplanin PF05808.11 EGO52921.1 - 0.031 14.4 0.3 0.14 12.3 0.1 2.1 2 0 0 2 2 2 0 Podoplanin SKG6 PF08693.10 EGO52921.1 - 0.067 12.6 1.0 0.11 11.9 1.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Hep_59 PF07052.11 EGO52922.1 - 6.9e-22 78.2 0.2 2.5e-21 76.4 0.2 2.0 1 0 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 WD40 PF00400.32 EGO52924.1 - 2.8e-15 56.4 9.2 0.017 15.9 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO52924.1 - 1.5e-07 31.6 0.2 0.0049 17.1 0.2 4.2 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO52924.1 - 2.1e-05 23.4 2.6 0.0001 21.1 0.7 2.8 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGO52924.1 - 0.1 11.3 0.0 7.3 5.2 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like HA2 PF04408.23 EGO52925.1 - 1.8e-22 79.6 2.0 7.8e-22 77.6 0.0 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGO52925.1 - 6.2e-17 61.7 0.0 1.3e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold TadF PF16964.5 EGO52925.1 - 5.2 6.8 5.2 0.65 9.7 0.4 1.8 2 0 0 2 2 2 0 Putative tight adherence pilin protein F GCV_T PF01571.21 EGO52926.1 - 1.7e-40 139.0 0.0 2.1e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EGO52926.1 - 3.3e-22 78.2 0.1 5.8e-22 77.4 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Choline_kinase PF01633.20 EGO52927.1 - 2.5e-56 190.7 0.0 3.6e-55 186.8 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EGO52927.1 - 2.2e-07 31.1 0.6 6.1e-07 29.6 0.2 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGO52927.1 - 0.11 11.8 0.0 0.92 8.8 0.0 2.2 1 1 0 1 1 1 0 Ecdysteroid kinase DUF2451 PF10474.9 EGO52927.1 - 0.12 12.1 0.1 9.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) NPR3 PF03666.13 EGO52928.1 - 1.4e-144 482.4 0.3 1.4e-144 482.4 0.3 2.5 2 1 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 TetR_C_30 PF17939.1 EGO52928.1 - 0.0062 16.7 1.4 3.6 7.9 0.0 3.3 3 0 0 3 3 3 2 Tetracyclin repressor-like, C-terminal domain DUF1819 PF08849.11 EGO52928.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) HLH PF00010.26 EGO52929.1 - 3.6e-12 46.0 0.1 1.6e-11 44.0 0.1 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Got1 PF04178.12 EGO52930.1 - 3.5e-36 124.1 15.1 4.9e-36 123.6 15.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 EGO52930.1 - 5.2 5.2 8.9 6.5 4.9 8.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Herpes_LMP1 PF05297.11 EGO52930.1 - 7.4 5.7 10.7 10 5.2 10.7 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) La PF05383.17 EGO52934.1 - 1.5e-19 69.8 0.0 2.7e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 La domain HLH PF00010.26 EGO52935.1 - 0.0023 17.9 0.0 0.0031 17.4 0.0 1.4 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Retrotran_gag_2 PF14223.6 EGO52935.1 - 0.1 12.2 0.3 0.1 12.2 0.3 1.5 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type MWFE PF15879.5 EGO52936.1 - 0.032 14.4 0.5 0.032 14.4 0.5 2.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase MWFE subunit Cluap1 PF10234.9 EGO52936.1 - 0.93 8.8 5.1 1.5 8.2 5.1 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 TPR_14 PF13428.6 EGO52938.1 - 7e-27 91.8 22.4 3.8e-06 27.3 0.3 10.7 9 3 3 12 12 12 6 Tetratricopeptide repeat HAT PF02184.16 EGO52938.1 - 3.6e-26 90.8 59.3 7.5e-11 41.8 1.3 12.4 13 0 0 13 13 13 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 EGO52938.1 - 1.1e-19 70.7 0.1 7.1e-08 32.9 0.0 7.1 6 1 2 8 8 7 2 Tetratricopeptide repeat Suf PF05843.14 EGO52938.1 - 2.3e-17 63.9 14.9 0.00025 21.2 1.2 7.2 3 2 4 7 7 7 4 Suppressor of forked protein (Suf) TPR_15 PF13429.6 EGO52938.1 - 1.6e-09 37.4 12.3 0.0042 16.3 1.5 6.2 2 1 5 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 EGO52938.1 - 8.1e-08 32.4 14.8 1.1 10.1 0.0 8.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGO52938.1 - 9.3e-07 29.4 10.3 0.075 13.7 0.2 7.3 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGO52938.1 - 5.2e-05 23.3 0.1 7.7 7.2 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGO52938.1 - 7.7e-05 22.6 0.0 51 4.5 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGO52938.1 - 0.00033 20.7 2.0 1.6 8.9 0.2 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGO52938.1 - 0.0011 19.0 8.6 0.72 10.0 0.0 6.0 7 0 0 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 EGO52938.1 - 0.0069 16.4 17.7 0.044 13.9 0.1 8.3 10 0 0 10 10 10 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO52938.1 - 0.012 15.8 1.2 0.79 10.0 0.0 4.0 5 0 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 QIL1 PF15884.5 EGO52938.1 - 0.025 15.2 1.4 2.6 8.7 0.0 4.5 5 0 0 5 5 5 0 MICOS complex subunit MIC13, QIL1 TPR_12 PF13424.6 EGO52938.1 - 0.031 14.6 15.8 4.4 7.7 0.1 6.8 9 0 0 9 9 8 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 EGO52938.1 - 0.033 14.2 0.8 0.033 14.2 0.8 6.8 6 3 1 7 7 7 0 U3 small nucleolar RNA-associated protein 6 Nop PF01798.18 EGO52939.1 - 1.1e-67 228.0 0.0 1.5e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EGO52939.1 - 8.7e-46 155.8 1.8 8.7e-46 155.8 1.8 2.0 2 0 0 2 2 2 1 Prp31 C terminal domain zf-C2H2 PF00096.26 EGO52942.1 - 3.6e-05 24.0 10.0 0.0024 18.2 0.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO52942.1 - 0.0092 16.7 8.1 0.14 13.0 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGO52942.1 - 0.016 15.6 1.1 0.016 15.6 1.1 2.7 3 0 0 3 3 3 0 Zinc-finger double domain Integrin_B_tail PF07965.12 EGO52942.1 - 0.029 14.8 1.4 0.091 13.3 0.1 2.0 1 1 1 2 2 2 0 Integrin beta tail domain zf-C2H2_8 PF15909.5 EGO52942.1 - 0.14 12.4 3.7 1.1 9.5 0.3 2.3 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-TRAF PF02176.18 EGO52942.1 - 0.89 10.3 5.3 2.3 9.0 0.7 2.3 1 1 1 2 2 2 0 TRAF-type zinc finger zf-met PF12874.7 EGO52942.1 - 1.1 9.8 6.1 6.5 7.3 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Acetate_kinase PF00871.17 EGO52944.1 - 1.9e-81 273.7 0.0 3.4e-81 272.9 0.0 1.3 1 1 0 1 1 1 1 Acetokinase family FEZ PF07763.13 EGO52944.1 - 0.13 12.0 0.0 0.56 9.9 0.0 1.9 2 0 0 2 2 2 0 FEZ-like protein HTH_38 PF13936.6 EGO52945.1 - 0.00074 19.2 0.3 0.31 10.8 0.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain Cas9_a PF18470.1 EGO52945.1 - 0.013 15.1 0.1 0.013 15.1 0.1 1.5 2 0 0 2 2 2 0 Cas9 alpha-helical lobe domain HTH_23 PF13384.6 EGO52945.1 - 0.015 15.1 0.0 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain Suf PF05843.14 EGO52945.1 - 0.06 13.3 9.3 0.085 12.8 9.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 EGO52945.1 - 0.062 13.3 15.7 0.073 13.1 15.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EGO52945.1 - 0.27 11.9 13.8 0.44 11.2 13.8 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Plasmodium_Vir PF05795.11 EGO52945.1 - 1.5 8.1 4.1 2 7.7 4.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ALMT PF11744.8 EGO52945.1 - 1.8 7.3 4.6 2.3 7.0 4.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PI31_Prot_C PF08577.11 EGO52945.1 - 2 9.6 9.0 19 6.5 9.0 2.3 1 1 0 1 1 1 0 PI31 proteasome regulator STT3 PF02516.14 EGO52947.1 - 9.4e-142 473.4 34.8 3.1e-137 458.5 32.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Ribosomal_L29 PF00831.23 EGO52948.1 - 1.1e-16 60.5 1.1 1.1e-16 60.5 1.1 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.19 EGO52948.1 - 0.027 15.0 0.8 0.035 14.6 0.8 1.2 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Ribosomal_L6e PF01159.19 EGO52949.1 - 4.1e-40 136.8 0.5 7e-40 136.0 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e V-SNARE_C PF12352.8 EGO52950.1 - 4.4e-13 49.3 0.3 4.4e-13 49.3 0.3 3.1 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus MetOD2 PF18548.1 EGO52950.1 - 0.057 13.5 5.3 7.8 6.7 0.2 3.5 2 2 2 4 4 4 0 Metanogen output domain 2 Dynactin_p22 PF07426.11 EGO52950.1 - 0.21 11.4 2.1 2 8.2 0.0 2.8 1 1 1 3 3 3 0 Dynactin subunit p22 CHDCT2 PF08074.11 EGO52950.1 - 0.34 11.1 2.4 0.95 9.6 2.4 1.8 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain MscS_porin PF12795.7 EGO52950.1 - 2.9 7.4 14.3 0.74 9.3 8.6 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain CorA PF01544.18 EGO52950.1 - 6.7 5.9 11.7 0.96 8.7 4.9 2.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein ATP-synt_10 PF05176.14 EGO52951.1 - 2.8e-79 266.0 0.0 3.6e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein 2-oxoacid_dh PF00198.23 EGO52952.1 - 2.9e-74 249.4 0.0 4.5e-74 248.8 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGO52952.1 - 1.2e-17 63.5 0.2 2.2e-17 62.7 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EGO52952.1 - 2.8e-15 56.4 0.1 6.5e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 e3 binding domain DUF4148 PF13663.6 EGO52952.1 - 0.15 12.3 3.7 0.62 10.3 3.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) GRP PF07172.11 EGO52954.1 - 0.00011 22.9 4.1 0.00016 22.3 4.1 1.2 1 0 0 1 1 1 1 Glycine rich protein family Keratin_2_head PF16208.5 EGO52954.1 - 0.05 13.7 9.6 0.061 13.5 9.6 1.1 1 0 0 1 1 1 0 Keratin type II head SKI PF01202.22 EGO52956.1 - 5.5e-12 46.1 0.0 7.4e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 EGO52956.1 - 2.5e-10 41.0 0.0 6.2e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO52956.1 - 2.6e-07 30.9 0.0 3.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EGO52956.1 - 9.8e-07 28.7 0.0 5e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Cytidylate kinase AAA_17 PF13207.6 EGO52956.1 - 5.4e-06 26.9 0.0 1.2e-05 25.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO52956.1 - 4.3e-05 24.0 0.0 5.1e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGO52956.1 - 4.6e-05 23.7 0.0 8.8e-05 22.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.15 EGO52956.1 - 7.3e-05 22.8 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 EGO52956.1 - 0.00016 22.1 0.0 0.0011 19.3 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 EGO52956.1 - 0.00093 19.1 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase RNA_helicase PF00910.22 EGO52956.1 - 0.0039 17.6 0.0 0.01 16.2 0.0 1.7 2 0 0 2 2 1 1 RNA helicase PRK PF00485.18 EGO52956.1 - 0.0048 16.7 0.0 0.043 13.6 0.0 2.0 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 EGO52956.1 - 0.0051 16.8 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 EGO52956.1 - 0.006 16.5 0.0 0.0093 15.9 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase ABC_tran PF00005.27 EGO52956.1 - 0.0076 16.8 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 EGO52956.1 - 0.014 15.6 0.0 0.033 14.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGO52956.1 - 0.018 15.0 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EGO52956.1 - 0.019 14.8 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGO52956.1 - 0.02 14.8 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Ploopntkinase1 PF18748.1 EGO52956.1 - 0.027 14.0 0.0 0.46 10.0 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 CoaE PF01121.20 EGO52956.1 - 0.032 13.9 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_14 PF13173.6 EGO52956.1 - 0.033 14.2 0.0 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain tRNA_lig_kinase PF08303.11 EGO52956.1 - 0.056 13.5 0.0 0.14 12.3 0.0 1.7 1 1 0 1 1 1 0 tRNA ligase kinase domain AAA_29 PF13555.6 EGO52956.1 - 0.056 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 EGO52956.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 EGO52956.1 - 0.059 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.6 EGO52956.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase-like family Zeta_toxin PF06414.12 EGO52956.1 - 0.091 12.0 0.0 0.17 11.1 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 EGO52956.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.17 EGO52956.1 - 0.093 12.4 0.0 12 5.5 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase Viral_helicase1 PF01443.18 EGO52956.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 EGO52956.1 - 0.22 11.4 0.0 0.57 10.1 0.0 1.6 2 0 0 2 2 2 0 NTPase Peptidase_M49 PF03571.15 EGO52957.1 - 2.3e-227 755.8 0.0 1.5e-194 647.4 0.0 2.0 1 1 1 2 2 2 2 Peptidase family M49 CdiA_C_tRNase PF18664.1 EGO52957.1 - 0.026 14.7 0.0 0.098 12.9 0.0 2.0 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain DUF3074 PF11274.8 EGO52958.1 - 4e-49 167.1 0.0 5.2e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) FlaC_arch PF05377.11 EGO52958.1 - 0.2 12.1 0.0 0.4 11.1 0.0 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Zwilch PF09817.9 EGO52958.1 - 0.24 9.8 0.0 0.33 9.4 0.0 1.1 1 0 0 1 1 1 0 RZZ complex, subunit zwilch zf-H2C2_2 PF13465.6 EGO52959.1 - 5.2e-21 74.1 32.7 1.1e-08 35.1 0.1 6.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 EGO52959.1 - 3e-18 65.2 45.8 1.3e-05 25.3 1.1 8.4 8 0 0 8 8 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO52959.1 - 8.4e-17 60.4 36.7 0.00023 21.7 0.8 8.0 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGO52959.1 - 1.6e-10 40.7 27.8 0.002 18.1 2.5 5.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EGO52959.1 - 0.0077 16.0 18.6 4.2 7.2 0.0 6.4 6 0 0 6 6 6 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 EGO52959.1 - 0.008 16.4 22.7 0.44 10.9 0.9 5.6 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 EGO52959.1 - 0.026 14.8 11.0 0.47 10.8 1.1 4.2 2 1 2 4 4 4 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 EGO52959.1 - 0.026 14.4 0.3 0.026 14.4 0.3 4.1 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf_ZIC PF18366.1 EGO52959.1 - 0.07 13.3 0.2 0.07 13.3 0.2 3.9 4 1 1 5 5 4 0 Zic proteins zinc finger domain GAGA PF09237.11 EGO52959.1 - 0.48 10.3 0.0 0.48 10.3 0.0 3.2 2 1 2 4 4 4 0 GAGA factor Zap1_zf2 PF18217.1 EGO52959.1 - 0.63 10.1 0.0 0.63 10.1 0.0 4.3 5 0 0 5 5 5 0 Zap1 zinc finger 2 zf-C2H2_9 PF16293.5 EGO52959.1 - 2.8 7.9 11.0 1.3 9.0 0.1 3.9 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) DEAD PF00270.29 EGO52962.1 - 1.4e-51 174.8 0.0 4.4e-50 169.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO52962.1 - 1.8e-27 95.9 0.0 4.5e-27 94.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO52962.1 - 0.00045 20.3 0.0 0.00096 19.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HMG_box PF00505.19 EGO52963.1 - 3.6e-15 56.1 10.8 1.5e-09 38.1 0.4 3.0 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO52963.1 - 2.9e-12 47.0 5.5 4.9e-09 36.6 0.6 2.9 3 0 0 3 3 3 2 HMG-box domain Tis11B_N PF04553.12 EGO52963.1 - 0.02 15.4 2.7 0.04 14.5 2.7 1.4 1 0 0 1 1 1 0 Tis11B like protein, N terminus Sin3a_C PF16879.5 EGO52963.1 - 0.042 13.6 2.4 0.049 13.3 0.3 1.9 2 0 0 2 2 2 0 C-terminal domain of Sin3a protein DUF3106 PF11304.8 EGO52963.1 - 0.38 11.3 7.4 10 6.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) Ndc1_Nup PF09531.10 EGO52963.1 - 4.7 5.8 7.1 5.2 5.6 7.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup 3Beta_HSD PF01073.19 EGO52965.1 - 2.1e-65 220.5 0.0 2.5e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGO52965.1 - 8.9e-33 113.7 0.2 1.2e-32 113.3 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO52965.1 - 3e-21 76.2 0.1 6.7e-18 65.2 0.1 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGO52965.1 - 1.6e-14 53.7 1.7 8.7e-12 44.8 0.4 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EGO52965.1 - 3.1e-14 52.7 0.1 3.7e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGO52965.1 - 2.2e-10 40.7 0.1 3.1e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGO52965.1 - 1.1e-08 34.6 0.4 5e-08 32.4 0.3 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EGO52965.1 - 4.5e-05 23.4 3.3 0.00021 21.2 3.3 1.9 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 EGO52965.1 - 0.00011 21.8 0.2 0.00021 21.0 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 EGO52965.1 - 0.0012 19.1 0.1 0.0022 18.3 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EGO52965.1 - 0.0056 16.9 0.6 0.042 14.1 0.6 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Nop14 PF04147.12 EGO52966.1 - 0.017 13.4 10.3 0.022 13.0 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EGO52966.1 - 0.028 13.8 12.6 0.039 13.4 12.6 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EGO52966.1 - 0.7 9.2 14.3 1.2 8.4 14.3 1.3 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 EGO52966.1 - 1.9 7.0 18.6 0.11 11.1 13.5 1.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CobT PF06213.12 EGO52966.1 - 4.4 6.6 12.8 7.7 5.8 12.8 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 EGO52966.1 - 5.8 5.1 10.0 9.8 4.3 10.0 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2417 PF10329.9 EGO52968.1 - 3.6e-64 216.4 4.2 6.3e-53 179.6 2.6 2.1 1 1 1 2 2 2 2 Region of unknown function (DUF2417) K_trans PF02705.16 EGO52968.1 - 0.77 8.2 4.8 1.1 7.7 4.8 1.2 1 0 0 1 1 1 0 K+ potassium transporter Virul_fac_BrkB PF03631.15 EGO52968.1 - 7.5 6.1 12.7 7.5 6.1 3.4 2.2 1 1 1 2 2 2 0 Virulence factor BrkB RhoGAP PF00620.27 EGO52969.1 - 4.5e-34 117.5 0.0 8.3e-34 116.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EGO52969.1 - 1.6e-30 105.1 40.0 9.4e-11 41.8 6.3 5.1 5 0 0 5 5 5 4 LIM domain zf_C2H2_13 PF18508.1 EGO52969.1 - 0.04 13.5 0.1 0.22 11.1 0.1 2.3 1 0 0 1 1 1 0 Zinc finger domain UQ_con PF00179.26 EGO52970.1 - 1.8e-41 141.1 0.0 3.2e-30 104.6 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO52970.1 - 5.7e-05 22.8 0.0 0.034 13.8 0.0 2.4 2 0 0 2 2 2 2 Prokaryotic E2 family B UEV PF05743.13 EGO52970.1 - 0.0088 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 UEV domain Rep_fac_C PF08542.11 EGO52971.1 - 2.7e-20 72.6 0.0 5.1e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EGO52971.1 - 1.7e-15 57.6 0.0 4.3e-15 56.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGO52971.1 - 7e-12 45.4 0.0 3.5e-10 39.9 0.0 2.5 2 1 0 2 2 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EGO52971.1 - 3.8e-09 36.7 0.0 9.6e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 EGO52971.1 - 1.4e-05 24.9 0.0 3.4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGO52971.1 - 3.4e-05 24.1 0.0 0.00082 19.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO52971.1 - 4.2e-05 24.0 0.1 0.0008 19.8 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_11 PF13086.6 EGO52971.1 - 5.3e-05 23.1 0.0 0.0001 22.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 EGO52971.1 - 0.00024 21.4 0.1 0.00067 19.9 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 EGO52971.1 - 0.0004 20.2 0.0 0.00075 19.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 EGO52971.1 - 0.00085 18.8 0.0 0.015 14.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EGO52971.1 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGO52971.1 - 0.0023 18.3 0.3 0.015 15.7 0.0 2.3 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGO52971.1 - 0.0027 17.4 0.0 0.024 14.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 EGO52971.1 - 0.0041 16.3 0.0 0.0063 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 EGO52971.1 - 0.0059 16.9 0.0 0.02 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGO52971.1 - 0.0065 16.2 0.0 0.026 14.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGO52971.1 - 0.0068 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 EGO52971.1 - 0.012 15.6 0.1 0.13 12.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 EGO52971.1 - 0.021 14.1 0.0 0.045 13.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EGO52971.1 - 0.025 14.6 0.0 0.17 11.8 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 EGO52971.1 - 0.04 14.5 0.0 0.11 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 EGO52971.1 - 0.097 12.4 0.7 1.2 8.9 0.0 2.6 2 1 0 3 3 3 0 DEAD/DEAH box helicase DUF4863 PF16155.5 EGO52971.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4863) RNA_helicase PF00910.22 EGO52971.1 - 0.11 12.8 0.0 0.26 11.7 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 EGO52971.1 - 0.15 12.5 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Spt5_N PF11942.8 EGO52972.1 - 0.86 10.6 6.5 16 6.5 2.9 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal KIP1 PF07765.12 EGO52972.1 - 1.1 9.4 3.5 7.3 6.8 0.2 3.3 3 0 0 3 3 3 0 KIP1-like protein Sec63 PF02889.16 EGO52973.1 - 1e-166 552.5 0.7 8.9e-93 310.1 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EGO52973.1 - 2.4e-50 170.7 0.0 5.1e-29 101.3 0.0 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EGO52973.1 - 6.5e-35 119.7 0.3 1.8e-34 118.3 0.3 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EGO52973.1 - 1e-24 87.4 0.0 1.5e-13 51.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGO52973.1 - 7.5e-12 45.6 0.0 4.1e-08 33.6 0.0 4.3 3 1 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGO52973.1 - 3.2e-08 33.9 0.2 0.023 15.0 0.1 3.4 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 EGO52973.1 - 7.7e-05 21.9 0.0 0.25 10.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_7 PF12775.7 EGO52973.1 - 0.0095 15.5 0.1 0.55 9.7 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region PhoH PF02562.16 EGO52973.1 - 0.01 15.3 0.0 0.51 9.8 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 EGO52973.1 - 0.014 15.1 0.1 1.9 8.2 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein TFIIE_alpha PF02002.17 EGO52973.1 - 0.032 14.1 0.3 22 5.0 0.0 3.4 3 0 0 3 3 3 0 TFIIE alpha subunit UvrD-helicase PF00580.21 EGO52973.1 - 0.052 13.1 0.0 0.97 8.9 0.0 2.8 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Sigma54_activat PF00158.26 EGO52973.1 - 0.094 12.4 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain PWWP PF00855.17 EGO52974.1 - 4.4e-13 49.4 0.7 4.4e-13 49.4 0.7 3.8 3 1 0 3 3 3 1 PWWP domain Med26 PF08711.11 EGO52974.1 - 0.0018 18.2 0.4 0.004 17.1 0.4 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain ORC3_N PF07034.11 EGO52975.1 - 5.1e-36 124.4 0.0 4.1e-35 121.4 0.0 2.1 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 EGO52975.1 - 6e-26 91.2 0.2 1.4e-14 54.3 0.0 3.0 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal DUF4375 PF14300.6 EGO52975.1 - 0.14 12.5 0.0 0.8 10.0 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4375) DUF2985 PF11204.8 EGO52975.1 - 0.14 12.3 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) DUF3294 PF07957.11 EGO52976.1 - 0.097 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Sec66 PF09802.9 EGO52977.1 - 1.2e-81 272.5 1.0 1.4e-81 272.4 1.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 rRNA_processing PF08524.11 EGO52977.1 - 0.044 13.8 0.2 0.089 12.8 0.2 1.5 1 0 0 1 1 1 0 rRNA processing PepSY_TM PF03929.16 EGO52977.1 - 0.063 12.9 0.2 0.1 12.2 0.2 1.4 1 1 0 1 1 1 0 PepSY-associated TM region DUF3848 PF12959.7 EGO52977.1 - 0.067 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) PEP-utilisers_N PF05524.13 EGO52977.1 - 0.28 11.3 3.6 0.36 11.0 2.9 1.5 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal NPL4 PF05021.15 EGO52978.1 - 7.7e-139 462.3 0.0 1e-138 461.9 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EGO52978.1 - 2e-68 229.1 0.0 3.3e-68 228.4 0.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region COesterase PF00135.28 EGO52979.1 - 6.1e-86 289.3 0.0 8e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO52979.1 - 0.0034 17.3 0.0 0.0082 16.0 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO52979.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4187 PF13821.6 EGO52980.1 - 1.9e-22 78.8 2.5 4e-22 77.8 2.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EGO52980.1 - 6.1e-10 38.8 0.9 1.1e-09 38.0 0.9 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGO52980.1 - 0.00094 19.2 0.6 0.0035 17.4 0.6 2.0 1 0 0 1 1 1 1 G-patch domain CAP_N PF01213.19 EGO52980.1 - 0.47 9.9 7.2 0.97 8.8 7.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EGO52980.1 - 0.56 10.2 6.1 0.9 9.6 5.8 1.5 1 1 0 1 1 1 0 Mitochondrial fission regulator CPSase_L_D2 PF02786.17 EGO52981.1 - 2.6e-112 373.5 0.1 4.8e-85 284.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EGO52981.1 - 1.6e-40 138.2 0.2 4.7e-40 136.7 0.2 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EGO52981.1 - 1.9e-22 79.7 0.3 1.2e-10 41.2 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGO52981.1 - 7.2e-19 68.1 1.0 1.5e-08 34.4 0.2 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EGO52981.1 - 4.8e-12 45.7 0.0 3e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 EGO52981.1 - 9.5e-07 28.8 0.5 0.038 13.8 0.2 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 EGO52981.1 - 2.4e-05 24.4 0.2 0.19 11.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 EGO52981.1 - 3.4e-05 23.4 0.1 0.038 13.4 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 EGO52981.1 - 9.5e-05 22.1 0.1 0.061 12.9 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 EGO52981.1 - 0.0022 17.6 0.0 0.03 13.9 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain Epimerase PF01370.21 EGO52981.1 - 0.046 13.2 0.0 0.25 10.8 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ATP-grasp_2 PF08442.10 EGO52981.1 - 0.14 11.7 0.2 3.4 7.2 0.0 2.9 3 0 0 3 3 3 0 ATP-grasp domain DUF1746 PF08508.10 EGO52982.1 - 9.1e-41 138.8 0.2 1.3e-40 138.3 0.2 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Connexin PF00029.19 EGO52982.1 - 0.064 13.0 0.2 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 EGO52982.1 - 0.26 9.5 2.0 0.37 9.0 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RTC PF01137.21 EGO52983.1 - 2.8e-30 105.2 0.2 3.4e-30 104.9 0.2 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EGO52983.1 - 5.5e-30 103.9 0.1 9.7e-30 103.1 0.1 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PPR_2 PF13041.6 EGO52984.1 - 2.5e-11 43.6 0.1 0.00099 19.3 0.0 5.1 4 0 0 4 4 4 3 PPR repeat family PPR PF01535.20 EGO52984.1 - 4.6e-05 23.4 1.5 2.1 8.8 0.0 5.4 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 EGO52984.1 - 0.00077 18.9 2.0 1.2 8.5 0.1 3.9 4 1 1 5 5 5 2 Pentacotripeptide-repeat region of PRORP BcrAD_BadFG PF01869.20 EGO52984.1 - 0.2 11.2 1.2 0.5 9.8 0.1 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family zf-C2H2 PF00096.26 EGO52988.1 - 2.2e-12 46.7 13.6 3.7e-06 27.1 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO52988.1 - 2.8e-08 33.9 11.1 0.0012 19.5 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGO52988.1 - 7.7e-07 29.3 12.9 1e-05 25.7 4.7 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EGO52988.1 - 0.0001 22.5 2.8 0.075 13.3 0.8 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGO52988.1 - 0.00021 21.6 4.5 0.026 14.9 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EGO52988.1 - 0.0014 18.6 14.3 0.12 12.4 1.2 2.8 2 1 0 2 2 2 2 C2H2-type zinc finger zf_UBZ PF18439.1 EGO52988.1 - 0.071 12.7 2.4 4.7 6.9 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 EGO52988.1 - 0.6 9.8 3.7 2.6 7.8 0.1 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_11 PF16622.5 EGO52988.1 - 0.61 9.9 7.9 3.4 7.5 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 EGO52988.1 - 2.4 8.4 4.8 15 5.8 0.5 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zf-BED PF02892.15 EGO52988.1 - 3.4 7.8 8.5 4.8 7.3 4.1 2.4 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_3rep PF18868.1 EGO52988.1 - 3.9 8.2 7.6 23 5.7 4.4 2.8 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Elf1 PF05129.13 EGO52988.1 - 6.1 7.0 6.7 15 5.7 1.0 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Diphthami_syn_2 PF01902.17 EGO52989.1 - 7.5e-23 81.2 0.0 1.4e-15 57.4 0.0 4.0 3 1 0 3 3 3 3 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EGO52989.1 - 1.6e-13 50.8 0.1 1.1e-08 35.2 0.0 3.9 4 0 0 4 4 4 2 Endoribonuclease L-PSP CENP-B_dimeris PF09026.10 EGO52989.1 - 0.13 12.6 21.6 0.13 12.7 2.1 4.4 4 0 0 4 4 4 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 EGO52989.1 - 7.1 6.6 14.1 2.7 8.0 1.8 3.8 4 0 0 4 4 4 0 RXT2-like, N-terminal Sortilin-Vps10 PF15902.5 EGO52990.1 - 1.4e-290 963.4 10.2 4e-151 503.8 1.0 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EGO52990.1 - 3.6e-88 294.3 23.3 6.2e-48 163.4 10.1 2.7 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EGO52990.1 - 5.5e-13 46.8 33.6 0.12 12.5 0.1 10.6 10 0 0 10 10 10 5 BNR/Asp-box repeat DUF2561 PF10812.8 EGO52990.1 - 0.044 13.8 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DSL PF01414.19 EGO52990.1 - 0.076 13.3 4.6 1.1 9.6 0.1 3.4 3 0 0 3 3 3 0 Delta serrate ligand PSII_BNR PF14870.6 EGO52990.1 - 0.083 12.1 5.5 1.1 8.4 0.0 4.0 5 0 0 5 5 5 0 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 EGO52990.1 - 0.18 11.9 18.8 0.67 10.2 0.0 6.8 9 0 0 9 9 9 0 BNR-Asp box repeat preSET_CXC PF18264.1 EGO52990.1 - 0.83 10.2 11.5 5.5 7.6 1.7 2.9 2 0 0 2 2 2 0 CXC domain CHB_HEX_C PF03174.13 EGO52990.1 - 1.1 9.3 6.7 5.4 7.1 0.2 4.7 5 0 0 5 5 5 0 Chitobiase/beta-hexosaminidase C-terminal domain SUN PF03856.13 EGO52991.1 - 1.7e-89 299.5 10.1 2.3e-89 299.1 10.1 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) zf-H2C2_2 PF13465.6 EGO52992.1 - 3.5e-09 36.7 9.9 7.3e-07 29.3 2.5 4.8 5 0 0 5 5 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 EGO52992.1 - 3.4e-07 30.4 33.0 0.005 17.2 8.1 4.5 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO52992.1 - 3.8e-07 30.4 22.0 0.039 14.8 6.6 4.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGO52992.1 - 0.0013 18.7 19.2 0.13 12.3 0.1 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger Rad50_zn_hook PF04423.14 EGO52992.1 - 0.0022 17.8 2.4 0.097 12.5 0.5 2.8 2 0 0 2 2 2 1 Rad50 zinc hook motif Baculo_PEP_C PF04513.12 EGO52992.1 - 0.0045 17.0 8.6 0.0059 16.7 7.7 1.6 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 EGO52992.1 - 0.0089 16.3 14.9 0.0089 16.3 14.9 3.2 2 1 1 3 3 2 1 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 EGO52992.1 - 0.0096 16.2 5.8 0.0096 16.2 5.8 2.0 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 REV PF00424.18 EGO52992.1 - 0.039 14.0 0.0 0.22 11.6 0.0 2.3 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Pox_A11 PF05061.13 EGO52992.1 - 0.047 13.0 1.2 0.078 12.3 1.2 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein zf-C2H2_9 PF16293.5 EGO52992.1 - 0.048 13.5 9.7 4 7.4 0.3 4.8 3 2 1 4 4 4 0 C2H2 type zinc-finger (1 copy) XhlA PF10779.9 EGO52992.1 - 0.056 13.7 2.8 0.055 13.7 0.9 1.9 1 1 1 2 2 2 0 Haemolysin XhlA Zn-ribbon_8 PF09723.10 EGO52992.1 - 0.1 12.8 5.4 0.28 11.3 1.7 2.7 2 0 0 2 2 2 0 Zinc ribbon domain EDR1 PF14381.6 EGO52992.1 - 0.24 11.1 2.8 0.4 10.4 2.8 1.2 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Gp58 PF07902.11 EGO52992.1 - 0.33 9.2 6.1 0.47 8.7 6.1 1.1 1 0 0 1 1 1 0 gp58-like protein TMF_DNA_bd PF12329.8 EGO52992.1 - 0.37 10.8 16.8 0.029 14.4 2.6 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding zf-C2HC_2 PF13913.6 EGO52992.1 - 0.37 10.7 6.2 0.2 11.6 0.7 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DZR PF12773.7 EGO52992.1 - 0.65 10.1 6.5 3.3 7.8 5.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-CHCC PF10276.9 EGO52992.1 - 1.1 9.4 7.2 0.98 9.5 0.3 2.8 3 0 0 3 3 2 0 Zinc-finger domain BRE1 PF08647.11 EGO52992.1 - 1.4 9.0 17.1 0.5 10.5 13.6 2.1 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase zinc_ribbon_9 PF14369.6 EGO52992.1 - 2.4 8.5 5.6 21 5.5 0.1 2.9 2 1 1 3 3 3 0 zinc-ribbon zf-FPG_IleRS PF06827.14 EGO52992.1 - 5.1 7.0 8.4 7.3 6.5 0.1 3.0 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DUF948 PF06103.11 EGO52992.1 - 8.7 6.7 7.2 9.5 6.6 5.3 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DAGAT PF03982.13 EGO52993.1 - 1.4e-93 313.0 0.0 2e-93 312.6 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase OAM_alpha PF16552.5 EGO52993.1 - 0.08 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit LAM_C PF12544.8 EGO52996.1 - 0.00039 20.6 0.0 0.00093 19.4 0.0 1.6 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 EGO52996.1 - 0.021 15.2 0.0 0.059 13.7 0.0 1.8 1 1 0 1 1 1 0 Radical SAM superfamily MFS_1 PF07690.16 EGO52997.1 - 1.7e-09 37.1 5.7 2.1e-09 36.8 5.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO52997.1 - 0.00045 19.2 1.7 0.00049 19.1 1.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter FtsX PF02687.21 EGO52997.1 - 0.33 11.5 3.7 0.26 11.8 0.2 2.3 1 1 1 2 2 2 0 FtsX-like permease family SHS2_Rpb7-N PF03876.17 EGO53000.1 - 3.7e-15 56.0 0.0 6.3e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EGO53000.1 - 1.7e-10 41.1 0.0 2.9e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 EGO53000.1 - 0.0058 16.9 0.1 0.014 15.7 0.0 1.6 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 DUF962 PF06127.11 EGO53001.1 - 3.5e-25 87.9 0.0 6e-25 87.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF3262 PF11660.8 EGO53001.1 - 2.5 8.5 5.6 14 6.2 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3262) Apq12 PF12716.7 EGO53002.1 - 1.3e-15 57.0 14.9 2.4e-15 56.2 14.9 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis DUF1700 PF08006.11 EGO53002.1 - 0.07 12.7 3.0 0.094 12.2 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) ATP_bind_1 PF03029.17 EGO53003.1 - 1.4e-72 244.3 0.0 3.6e-72 243.0 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 EGO53003.1 - 6.4e-05 22.8 0.0 0.00022 21.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain CLP1_P PF16575.5 EGO53003.1 - 0.00039 20.3 0.0 0.00099 18.9 0.0 1.7 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 EGO53003.1 - 0.00042 20.4 0.0 0.0013 18.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain TRADD_N PF09034.10 EGO53003.1 - 0.0015 18.6 0.1 0.0028 17.7 0.1 1.4 1 0 0 1 1 1 1 TRADD, N-terminal domain RNA_helicase PF00910.22 EGO53003.1 - 0.0031 17.9 0.0 0.0073 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase CbiA PF01656.23 EGO53003.1 - 0.0037 17.3 0.0 0.0051 16.9 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 EGO53003.1 - 0.0062 17.1 0.0 0.017 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGO53003.1 - 0.0096 16.2 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO53003.1 - 0.01 16.0 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EGO53003.1 - 0.012 15.3 0.0 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase AAA_17 PF13207.6 EGO53003.1 - 0.015 15.7 0.1 0.87 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 EGO53003.1 - 0.025 14.1 0.0 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGO53003.1 - 0.029 14.3 0.3 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 EGO53003.1 - 0.035 14.6 0.0 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 EGO53003.1 - 0.039 14.3 0.0 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 EGO53003.1 - 0.04 13.5 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Septin PF00735.18 EGO53003.1 - 0.043 13.1 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 EGO53003.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 EGO53003.1 - 0.07 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PPV_E1_C PF00519.17 EGO53003.1 - 0.073 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_29 PF13555.6 EGO53003.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 EGO53003.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase PduV-EutP PF10662.9 EGO53003.1 - 0.095 12.4 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EGO53003.1 - 0.16 12.1 0.0 0.55 10.3 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase S-AdoMet_synt_C PF02773.16 EGO53004.1 - 4.3e-66 221.1 0.1 8.8e-66 220.1 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 EGO53004.1 - 4e-44 149.3 0.4 8.7e-44 148.2 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 EGO53004.1 - 1.4e-43 147.9 0.0 2.7e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain YfcL PF08891.11 EGO53005.1 - 0.13 12.7 1.0 4 7.9 0.0 2.8 2 0 0 2 2 2 0 YfcL protein MFS_1 PF07690.16 EGO53006.1 - 2.2e-19 69.6 14.4 2.8e-13 49.5 7.7 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO53006.1 - 2e-05 23.6 14.9 0.00074 18.5 3.0 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Glyco_hydro_88 PF07470.13 EGO53007.1 - 3.5e-86 289.4 0.7 4e-86 289.2 0.7 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.16 EGO53008.1 - 3.3e-35 121.6 20.2 4.3e-35 121.3 20.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Microcin PF03526.13 EGO53008.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein Polyketide_cyc2 PF10604.9 EGO53009.1 - 0.03 14.6 0.1 0.071 13.4 0.1 1.7 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport NinD PF17466.2 EGO53009.1 - 0.072 13.2 3.4 5.4 7.2 0.1 2.6 2 1 0 2 2 2 0 Family of unknown function Methyltransf_32 PF13679.6 EGO53010.1 - 0.002 18.1 0.9 0.0046 16.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 EGO53010.1 - 0.011 15.8 0.0 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase PCI PF01399.27 EGO53011.1 - 4.6e-22 78.5 0.1 2.1e-21 76.4 0.1 2.1 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 EGO53011.1 - 3.2e-16 59.1 1.2 1.1e-15 57.4 1.2 2.0 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain CSN8_PSD8_EIF3K PF10075.9 EGO53011.1 - 0.048 13.6 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Methyltransf_23 PF13489.6 EGO53012.1 - 4.5e-20 72.1 0.0 8.9e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO53012.1 - 1.2e-08 35.6 0.0 7.2e-08 33.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO53012.1 - 8e-08 32.8 0.0 2.5e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO53012.1 - 1.3e-07 32.2 0.0 8.1e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO53012.1 - 7.5e-05 22.6 0.0 0.0003 20.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO53012.1 - 0.07 12.4 0.0 4.2 6.6 0.0 2.7 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EGO53012.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 EGO53015.1 - 1.1e-22 80.4 0.0 1.8e-22 79.7 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EGO53015.1 - 0.012 16.3 0.0 0.035 14.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 EGO53015.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Atrophin-1 PF03154.15 EGO53019.1 - 0.0024 16.2 3.5 0.0038 15.6 3.5 1.2 1 0 0 1 1 1 1 Atrophin-1 family DUF3357 PF11837.8 EGO53019.1 - 0.018 15.5 0.7 0.044 14.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DHC_N2 PF08393.13 EGO53019.1 - 0.022 13.9 1.5 0.044 12.9 1.5 1.5 1 1 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 SlyX PF04102.12 EGO53019.1 - 0.032 14.8 5.9 0.07 13.8 0.6 3.1 1 1 1 2 2 2 0 SlyX EMP24_GP25L PF01105.24 EGO53019.1 - 0.1 12.5 0.3 0.1 12.5 0.3 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD MCU PF04678.13 EGO53019.1 - 8.8 6.4 8.5 0.6 10.2 0.1 2.6 2 1 1 3 3 3 0 Mitochondrial calcium uniporter Cgr1 PF03879.14 EGO53020.1 - 3.2e-35 120.8 26.9 4.2e-35 120.4 26.9 1.2 1 0 0 1 1 1 1 Cgr1 family RR_TM4-6 PF06459.12 EGO53020.1 - 1.8 8.4 14.6 1.8 8.3 14.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.10 EGO53020.1 - 3.1 7.1 21.4 3.6 6.9 21.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Arginosuc_synth PF00764.19 EGO53021.1 - 3.7e-147 490.7 0.0 4.2e-147 490.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EGO53021.1 - 0.00039 20.0 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EGO53021.1 - 0.027 13.3 0.0 0.045 12.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase UQ_con PF00179.26 EGO53023.1 - 2.2e-30 105.2 0.0 2.5e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO53023.1 - 0.012 15.4 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 EGO53023.1 - 0.013 15.8 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain Anp1 PF03452.14 EGO53024.1 - 4.4e-108 360.7 0.0 5.2e-108 360.4 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 EGO53024.1 - 0.062 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Proteasom_Rpn13 PF04683.13 EGO53025.1 - 8.5e-27 93.5 0.0 1.3e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RRM_1 PF00076.22 EGO53026.1 - 2.3e-12 46.6 0.1 7e-05 22.6 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO53026.1 - 0.08 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Sulfate_transp PF00916.20 EGO53027.1 - 4.3e-59 200.2 12.8 6.5e-59 199.6 12.8 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 EGO53027.1 - 4.2e-17 62.0 0.0 7.6e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 EGO53027.1 - 1.5e-08 34.3 0.0 2.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain EAL PF00563.20 EGO53027.1 - 0.0047 16.5 0.0 0.0077 15.8 0.0 1.3 1 0 0 1 1 1 1 EAL domain Sld5 PF05916.11 EGO53028.1 - 1.1e-14 54.9 0.0 1.5e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein FliT PF05400.13 EGO53028.1 - 0.032 15.0 0.0 0.1 13.4 0.0 1.8 2 0 0 2 2 2 0 Flagellar protein FliT AAA_2 PF07724.14 EGO53029.1 - 1.3e-43 149.1 0.0 1.1e-42 146.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGO53029.1 - 4.8e-36 122.8 8.1 5.9e-36 122.5 2.4 2.6 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EGO53029.1 - 2.5e-26 91.5 0.2 9.2e-26 89.7 0.2 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EGO53029.1 - 2.5e-18 66.8 0.0 3.5e-10 40.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGO53029.1 - 1.3e-10 41.4 0.2 2.1e-08 34.3 0.0 3.0 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGO53029.1 - 1.4e-07 31.8 0.9 0.01 16.1 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGO53029.1 - 1.5e-07 32.0 4.0 0.019 15.4 0.2 4.1 2 2 0 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 EGO53029.1 - 5.2e-07 29.5 0.6 0.00048 19.9 0.0 2.5 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 EGO53029.1 - 2.2e-05 24.5 0.0 0.058 13.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 EGO53029.1 - 0.00015 21.3 0.0 0.014 14.8 0.0 3.3 2 1 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 EGO53029.1 - 0.00019 22.0 0.6 0.43 11.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 EGO53029.1 - 0.00069 19.2 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 EGO53029.1 - 0.0011 18.7 3.7 1 9.1 0.1 3.2 3 1 0 3 3 3 2 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EGO53029.1 - 0.0016 18.4 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase ATPase_2 PF01637.18 EGO53029.1 - 0.0018 18.2 6.2 3.2 7.6 0.0 4.1 3 2 1 5 5 5 2 ATPase domain predominantly from Archaea NACHT PF05729.12 EGO53029.1 - 0.0024 17.8 0.3 0.39 10.6 0.0 2.8 2 1 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 EGO53029.1 - 0.015 15.8 0.6 3.3 8.2 0.0 3.5 3 1 0 3 3 3 0 ABC transporter AAA_28 PF13521.6 EGO53029.1 - 0.017 15.3 1.1 3.6 7.8 0.0 3.6 3 1 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EGO53029.1 - 0.028 14.2 0.0 0.93 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGO53029.1 - 0.035 14.5 0.1 2.8 8.4 0.0 2.9 2 1 0 2 2 2 0 RNA helicase Roc PF08477.13 EGO53029.1 - 0.064 13.5 0.2 9.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 EGO53029.1 - 0.067 12.8 0.3 4.4 6.9 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 EGO53029.1 - 0.073 12.4 0.6 7.2 5.9 0.1 3.2 2 2 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EGO53029.1 - 0.26 11.6 1.3 4.8 7.5 0.1 3.0 2 1 1 3 3 3 0 AAA domain DUF4094 PF13334.6 EGO53029.1 - 0.64 10.5 2.3 1.5 9.3 0.4 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4094) TsaE PF02367.17 EGO53029.1 - 1.3 9.0 4.5 20 5.2 0.1 3.1 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE HAUS2 PF15003.6 EGO53029.1 - 1.3 8.7 5.7 1.2 8.8 3.3 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 2 BRE1 PF08647.11 EGO53029.1 - 4 7.6 12.0 3.2 7.9 4.7 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase AICARFT_IMPCHas PF01808.18 EGO53030.1 - 4.6e-90 302.0 0.0 6e-90 301.7 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EGO53030.1 - 4.6e-24 84.4 0.0 9.2e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain SH3_2 PF07653.17 EGO53031.1 - 0.0076 15.9 0.3 0.015 14.9 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain OmdA PF13376.6 EGO53031.1 - 0.12 12.4 0.4 0.29 11.2 0.4 1.7 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Kinesin PF00225.23 EGO53033.1 - 1.6e-96 323.1 0.0 3e-96 322.2 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGO53033.1 - 4.5e-21 75.3 0.1 1.9e-20 73.3 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding ALC PF17527.2 EGO53033.1 - 0.028 14.1 0.6 0.066 12.8 0.6 1.6 1 0 0 1 1 1 0 Phage ALC protein FapA PF03961.13 EGO53033.1 - 0.15 10.6 7.0 0.036 12.7 1.9 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A Tho2 PF11262.8 EGO53033.1 - 2.2 7.4 7.8 1.4 8.0 5.6 1.7 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF4407 PF14362.6 EGO53033.1 - 3.3 7.0 17.0 0.52 9.6 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) p450 PF00067.22 EGO53035.1 - 1.1e-70 238.6 0.0 1.4e-70 238.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HIG_1_N PF04588.13 EGO53036.1 - 1.1e-06 28.7 3.9 2.8e-06 27.4 3.9 1.7 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Bud13 PF09736.9 EGO53036.1 - 0.24 11.8 5.8 0.38 11.1 0.1 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex zf-C2H2_aberr PF17017.5 EGO53037.1 - 1.7e-05 25.0 1.0 0.024 14.8 0.1 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-H2C2_2 PF13465.6 EGO53037.1 - 0.00064 20.0 6.6 0.017 15.5 0.9 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EGO53037.1 - 0.001 19.4 13.2 0.12 12.9 1.6 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO53037.1 - 0.002 18.8 18.5 0.025 15.4 1.1 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGO53037.1 - 0.0056 16.9 5.8 2.2 8.7 0.3 4.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 EGO53037.1 - 1.2 9.6 3.6 0.6 10.6 0.9 1.9 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 EGO53037.1 - 5.5 7.5 9.1 5.2 7.6 0.5 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Kelch_1 PF01344.25 EGO53039.1 - 8.6e-42 140.5 18.9 7e-09 35.1 1.3 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 EGO53039.1 - 9.9e-38 127.6 23.0 2.2e-07 30.7 0.2 6.6 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 EGO53039.1 - 3.9e-37 125.9 18.3 2.8e-08 33.9 0.0 6.9 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EGO53039.1 - 8.2e-35 118.0 17.5 6.1e-07 29.5 0.2 6.4 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EGO53039.1 - 3.6e-33 112.3 14.6 7.4e-09 35.2 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGO53039.1 - 4e-33 113.2 17.4 6.6e-06 26.0 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Dus PF01207.17 EGO53040.1 - 6.6e-42 143.7 0.0 6.2e-33 114.2 0.0 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf_CCCH_4 PF18345.1 EGO53040.1 - 2 8.6 7.0 4.4 7.5 0.5 2.6 2 0 0 2 2 2 0 Zinc finger domain Peroxin-13_N PF04088.13 EGO53041.1 - 5.8e-21 75.3 0.0 8.7e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 EGO53041.1 - 8.1e-09 35.0 0.0 1.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGO53041.1 - 4e-06 26.3 0.1 1.7e-05 24.3 0.1 2.0 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGO53041.1 - 0.00014 21.7 0.0 0.00029 20.6 0.0 1.6 1 1 0 1 1 1 1 Variant SH3 domain Kelch_4 PF13418.6 EGO53042.1 - 9.1e-27 92.8 8.7 3.4e-08 33.4 0.0 5.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EGO53042.1 - 3.5e-24 84.3 2.2 8.5e-07 28.8 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 EGO53042.1 - 2.5e-23 81.5 2.7 7e-05 23.0 0.0 5.0 3 1 2 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EGO53042.1 - 1.1e-21 76.1 0.6 4.1e-05 23.1 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 EGO53042.1 - 1.5e-19 69.8 1.3 2.3e-07 30.9 0.1 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EGO53042.1 - 7e-17 60.7 2.4 0.0019 18.1 0.0 4.7 4 0 0 4 4 4 4 Kelch motif BTB PF00651.31 EGO53042.1 - 4.2e-09 36.6 0.0 7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain ANAPC4_WD40 PF12894.7 EGO53043.1 - 1.2e-16 60.7 3.8 4.1e-05 23.8 0.3 4.3 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO53043.1 - 2.3e-16 59.9 18.5 0.00033 21.4 0.1 6.4 6 1 1 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EGO53043.1 - 6.5e-06 25.3 0.0 0.00038 19.5 0.0 3.1 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGO53043.1 - 1.1e-05 25.4 0.2 0.0007 19.5 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A TFIIA PF03153.13 EGO53044.1 - 1.3e-97 328.5 21.8 1.5e-97 328.2 21.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 EGO53044.1 - 0.012 14.9 12.3 0.014 14.6 12.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PAS_3 PF08447.12 EGO53044.1 - 0.13 12.5 0.1 0.4 11.0 0.1 1.8 1 0 0 1 1 1 0 PAS fold DNA_pol_phi PF04931.13 EGO53044.1 - 1.9 6.5 7.9 2.8 5.9 7.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EGO53044.1 - 8.1 5.7 10.9 13 5.0 10.9 1.2 1 0 0 1 1 1 0 NOA36 protein Pro_isomerase PF00160.21 EGO53045.1 - 2.2e-50 171.0 0.1 2.5e-50 170.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 EGO53045.1 - 0.029 14.4 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain DUF1382 PF07131.11 EGO53046.1 - 0.065 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) TEA PF01285.18 EGO53047.1 - 7.8e-16 57.9 0.2 2e-15 56.6 0.2 1.7 1 0 0 1 1 1 1 TEA/ATTS domain DUF4663 PF15668.5 EGO53047.1 - 0.69 8.9 5.5 0.09 11.8 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4663) RRM_1 PF00076.22 EGO53048.1 - 2.2e-66 219.6 4.8 4.7e-16 58.4 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO53048.1 - 2.3e-09 37.0 0.0 0.24 11.3 0.0 5.1 5 0 0 5 5 5 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGO53048.1 - 3.1e-09 36.7 0.1 0.0062 16.5 0.0 4.7 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 EGO53048.1 - 7e-07 29.2 0.8 0.048 13.7 0.0 5.0 4 1 0 4 4 4 1 Limkain b1 RRM_7 PF16367.5 EGO53048.1 - 1.9e-05 24.7 0.1 1.6 8.9 0.0 4.1 4 0 0 4 4 4 2 RNA recognition motif Smg4_UPF3 PF03467.15 EGO53048.1 - 0.00011 22.3 0.0 0.094 12.7 0.0 2.9 2 0 0 2 2 2 2 Smg-4/UPF3 family Nup35_RRM PF05172.13 EGO53048.1 - 0.00078 19.4 0.0 0.011 15.7 0.0 2.9 3 1 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EGO53048.1 - 0.002 17.7 0.0 0.079 12.5 0.0 3.0 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGO53048.1 - 0.047 13.7 1.5 7.3 6.7 0.0 4.4 5 0 0 5 5 5 0 RNA binding motif NOP5NT PF08156.13 EGO53048.1 - 0.056 13.8 0.5 0.44 11.0 0.5 2.7 1 0 0 1 1 1 0 NOP5NT (NUC127) domain Dynein_light PF01221.18 EGO53049.1 - 2.2e-40 136.8 1.8 2.6e-40 136.6 1.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Methyltransf_16 PF10294.9 EGO53051.1 - 1.3e-22 80.4 0.0 3e-22 79.2 0.0 1.5 2 0 0 2 2 2 1 Lysine methyltransferase PrmA PF06325.13 EGO53051.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Helo_like_N PF17111.5 EGO53053.1 - 0.17 11.2 1.3 3.5 6.9 0.0 2.6 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins KIND PF16474.5 EGO53053.1 - 0.51 10.2 4.2 0.95 9.3 0.3 2.5 1 1 1 2 2 2 0 Kinase non-catalytic C-lobe domain RNA_pol_N PF01194.17 EGO53056.1 - 1.4e-30 105.4 0.7 1.8e-30 105.0 0.7 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 EGO53056.1 - 0.0037 17.5 0.2 0.0055 16.9 0.2 1.3 1 0 0 1 1 1 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) MmgE_PrpD PF03972.14 EGO53056.1 - 0.048 12.2 0.0 0.051 12.1 0.0 1.0 1 0 0 1 1 1 0 MmgE/PrpD family WD40 PF00400.32 EGO53057.1 - 4e-08 33.8 5.4 0.026 15.4 0.1 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO53057.1 - 0.0017 18.6 0.0 4.9 7.5 0.0 4.9 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain KcnmB2_inactiv PF09303.10 EGO53057.1 - 0.0019 17.9 0.2 0.0076 16.0 0.0 2.1 2 0 0 2 2 2 1 KCNMB2, ball and chain domain RNA_pol_3_Rpc31 PF11705.8 EGO53057.1 - 0.041 14.1 0.2 0.041 14.1 0.2 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 BBS2_N PF14781.6 EGO53057.1 - 0.19 11.6 0.3 1.2 9.0 0.1 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal DIOX_N PF14226.6 EGO53059.1 - 1.5e-32 112.8 0.0 1.1e-30 106.8 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGO53059.1 - 9.4e-14 51.7 0.0 3.2e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily GxGYxYP_C PF14323.6 EGO53059.1 - 0.017 15.0 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain HHH PF00633.23 EGO53060.1 - 0.019 14.8 0.3 0.059 13.3 0.3 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF1479 PF07350.12 EGO53061.1 - 2.1e-131 438.6 1.8 2.4e-130 435.0 0.1 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 EGO53061.1 - 0.015 15.6 0.0 4.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Bap31 PF05529.12 EGO53062.1 - 1.2e-49 167.7 9.2 1.6e-49 167.3 9.2 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EGO53062.1 - 1e-13 51.0 3.8 1e-13 51.0 3.8 2.3 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain Filament PF00038.21 EGO53062.1 - 0.0055 16.3 1.6 0.0073 15.9 1.6 1.2 1 0 0 1 1 1 1 Intermediate filament protein DivIC PF04977.15 EGO53062.1 - 0.043 13.6 5.4 0.23 11.2 0.5 3.1 3 1 1 4 4 4 0 Septum formation initiator GPS2_interact PF15784.5 EGO53062.1 - 0.048 14.1 3.6 0.063 13.7 3.2 1.5 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Csm1_N PF18504.1 EGO53062.1 - 0.071 13.5 0.9 0.071 13.5 0.9 2.1 2 0 0 2 2 2 0 Csm1 N-terminal domain She9_MDM33 PF05546.11 EGO53062.1 - 0.81 9.5 5.7 0.087 12.6 0.7 1.9 2 0 0 2 2 2 0 She9 / Mdm33 family Amidohydro_1 PF01979.20 EGO53064.1 - 7e-21 74.9 0.1 3.6e-20 72.6 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGO53064.1 - 1.9e-06 27.6 1.7 2.4e-05 24.0 1.2 2.3 2 1 0 2 2 2 1 Amidohydrolase family zf-BED PF02892.15 EGO53066.1 - 2e-05 24.5 0.1 2.8e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 BED zinc finger zf-H2C2_5 PF13909.6 EGO53066.1 - 0.032 14.0 1.5 0.095 12.5 1.5 1.7 1 1 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 EGO53066.1 - 0.08 13.4 0.1 0.1 13.1 0.1 1.3 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger DUF1687 PF07955.11 EGO53067.1 - 3.7e-30 105.0 0.0 4.7e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.15 EGO53067.1 - 0.031 14.3 0.0 0.073 13.1 0.0 1.6 2 0 0 2 2 2 0 ArsC family RRM_1 PF00076.22 EGO53068.1 - 0.00011 22.0 0.0 0.00078 19.2 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGO53068.1 - 0.083 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF3716 PF12511.8 EGO53069.1 - 1.4e-08 34.6 4.4 2.4e-08 33.9 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Sel1 PF08238.12 EGO53070.1 - 3.4e-48 161.0 21.8 2.5e-08 34.3 0.0 7.6 7 0 0 7 7 7 7 Sel1 repeat MBOAT PF03062.19 EGO53071.1 - 5.5e-44 150.9 18.3 9.8e-44 150.1 18.3 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SDA1 PF05285.12 EGO53072.1 - 0.0026 17.2 11.8 0.005 16.3 11.8 1.4 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 EGO53072.1 - 0.043 12.0 18.0 0.07 11.3 18.0 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EGO53072.1 - 0.8 7.9 14.7 1.8 6.8 14.7 1.5 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 EGO53072.1 - 1.2 9.4 26.6 0.97 9.6 20.3 3.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Afi1 PF07792.12 EGO53072.1 - 2.7 8.5 14.0 9 6.8 14.0 1.8 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RXT2_N PF08595.11 EGO53072.1 - 4.4 7.3 12.3 13 5.8 12.3 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal Astro_capsid_p PF12226.8 EGO53072.1 - 7.4 5.6 15.3 15 4.7 15.3 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FYDLN_acid PF09538.10 EGO53072.1 - 8.9 7.1 19.4 43 4.8 19.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Prefoldin_3 PF13758.6 EGO53073.1 - 3e-31 107.4 0.2 3e-31 107.4 0.2 2.6 2 1 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.7 EGO53073.1 - 1.8e-27 96.0 0.6 2e-26 92.6 0.1 4.7 3 1 1 4 4 4 2 Domain of unknown function (DUF3835) Pox_MCEL PF03291.16 EGO53073.1 - 0.021 13.9 0.4 0.097 11.8 0.1 2.0 2 0 0 2 2 2 0 mRNA capping enzyme DUF4718 PF15842.5 EGO53073.1 - 0.74 9.6 3.0 1.4 8.7 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) CS PF04969.16 EGO53074.1 - 2.1e-19 70.3 0.5 5.9e-19 68.9 0.0 2.0 3 0 0 3 3 3 1 CS domain UPF0102 PF02021.17 EGO53074.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0102 MAT1 PF06391.13 EGO53075.1 - 1.1e-34 120.1 5.4 1.4e-34 119.8 5.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EGO53075.1 - 1.2e-29 102.0 11.4 1.9e-29 101.3 11.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO53075.1 - 1.9e-05 24.4 6.0 2.8e-05 23.9 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MRP-S26 PF14943.6 EGO53075.1 - 7.6e-05 22.7 13.2 0.00011 22.2 13.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 zf-C3HC4 PF00097.25 EGO53075.1 - 0.00093 19.0 3.3 0.0021 17.9 3.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO53075.1 - 0.019 14.9 8.8 0.073 13.0 9.0 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGO53075.1 - 0.019 15.0 6.4 0.034 14.2 6.4 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 EGO53075.1 - 0.025 14.9 6.7 0.038 14.3 6.7 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 EGO53075.1 - 0.03 14.1 7.4 0.055 13.3 7.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EGO53075.1 - 0.085 12.7 7.5 0.22 11.3 3.6 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EGO53075.1 - 0.1 12.2 2.0 0.2 11.3 2.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EGO53075.1 - 0.97 9.6 5.1 2.5 8.3 5.1 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 EGO53075.1 - 2.2 8.5 4.6 5.9 7.1 4.6 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger ANTH PF07651.16 EGO53076.1 - 2.2e-55 187.6 0.3 1.7e-41 142.1 0.0 2.4 1 1 1 2 2 2 2 ANTH domain ENTH PF01417.20 EGO53076.1 - 1.2e-07 31.8 0.0 2.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 ENTH domain tRNA-synt_2 PF00152.20 EGO53077.1 - 3.7e-87 292.3 0.0 5e-87 291.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EGO53077.1 - 0.093 12.2 0.1 5.2 6.5 0.0 2.5 2 1 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 EGO53077.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Glyco_hydro_31 PF01055.26 EGO53079.1 - 4.2e-147 490.9 4.1 6.2e-147 490.3 4.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EGO53079.1 - 5.8e-33 113.5 0.0 1.1e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase DUF5110 PF17137.4 EGO53079.1 - 0.037 14.3 0.0 0.15 12.4 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Rotavirus_VP7 PF05868.11 EGO53079.1 - 0.22 10.9 0.1 0.4 10.0 0.1 1.3 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 Sugar_tr PF00083.24 EGO53081.1 - 4.7e-124 414.7 20.0 5.7e-124 414.4 20.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO53081.1 - 3.3e-17 62.5 36.0 5.1e-14 52.0 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4834 PF16118.5 EGO53081.1 - 0.44 11.5 1.7 1.4 9.9 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 EGO53081.1 - 0.49 10.3 14.7 0.69 9.9 14.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EGO53081.1 - 2.6 7.6 20.8 4 7.0 20.8 1.2 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 EGO53081.1 - 4 6.2 14.4 6.3 5.5 14.4 1.2 1 0 0 1 1 1 0 Androgen receptor FAD_binding_2 PF00890.24 EGO53084.1 - 3.7e-85 286.5 0.6 5.2e-85 286.0 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EGO53084.1 - 9.5e-22 76.9 0.1 8.6e-21 73.9 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EGO53084.1 - 2.1e-15 57.1 0.3 3.9e-15 56.3 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGO53084.1 - 3e-09 36.7 1.6 1.8e-08 34.2 1.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO53084.1 - 4.7e-08 32.6 0.7 5.9e-07 29.0 0.5 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO53084.1 - 1.2e-07 31.9 2.4 3.7e-07 30.3 0.5 2.8 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGO53084.1 - 2.8e-06 26.3 1.9 0.0088 14.8 0.2 3.3 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 EGO53084.1 - 9.7e-06 25.0 0.1 0.11 11.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGO53084.1 - 9.8e-06 25.0 0.1 1.8e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EGO53084.1 - 0.00057 19.1 2.8 0.099 11.7 0.9 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 EGO53084.1 - 0.00065 19.1 1.4 0.23 10.7 0.2 3.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 EGO53084.1 - 0.0007 18.9 2.1 0.054 12.7 0.8 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 EGO53084.1 - 0.031 14.8 6.0 3.1 8.4 1.4 3.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGO53084.1 - 0.032 13.5 0.8 0.075 12.3 0.8 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sin3a_C PF16879.5 EGO53086.1 - 2e-73 247.6 4.0 2e-73 247.6 4.0 2.0 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 EGO53086.1 - 6.5e-39 131.8 4.4 8.1e-18 64.3 0.0 3.6 3 1 0 3 3 3 2 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EGO53086.1 - 5.1e-38 129.1 0.1 2.6e-37 126.8 0.0 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor Lge1 PF11488.8 EGO53086.1 - 0.023 14.9 0.1 0.082 13.1 0.1 2.0 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 Pollen_allerg_1 PF01357.21 EGO53086.1 - 0.024 14.6 0.6 0.17 11.9 0.4 2.2 2 0 0 2 2 2 0 Pollen allergen HEPN PF05168.14 EGO53086.1 - 0.028 14.6 0.1 0.074 13.2 0.1 1.8 1 0 0 1 1 1 0 HEPN domain MCM6_C PF18263.1 EGO53086.1 - 0.092 13.0 0.3 0.48 10.7 0.1 2.3 1 1 0 2 2 2 0 MCM6 C-terminal winged-helix domain Med3 PF11593.8 EGO53087.1 - 0.078 12.2 4.3 0.13 11.4 4.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Fungal_trans PF04082.18 EGO53088.1 - 9.2e-11 41.3 0.6 1.6e-10 40.4 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO53088.1 - 7e-07 29.3 9.6 1.4e-06 28.3 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FeS_assembly_P PF01883.19 EGO53092.1 - 4.5e-07 30.0 0.1 1.6e-06 28.2 0.1 1.9 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein GTP_EFTU PF00009.27 EGO53094.1 - 2.2e-47 161.1 0.0 3.2e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EGO53094.1 - 3e-36 124.7 6.6 5.8e-36 123.8 6.6 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EGO53094.1 - 2.4e-24 85.5 0.0 6.1e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EGO53094.1 - 7.8e-19 67.5 0.0 2.6e-18 65.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGO53094.1 - 1.9e-09 37.8 0.0 5.2e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGO53094.1 - 1.2e-06 28.5 0.0 2.9e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EGO53094.1 - 6.7e-05 22.9 0.1 0.00013 22.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Thiolase_N PF00108.23 EGO53095.1 - 2e-92 309.2 4.2 2e-92 309.2 4.2 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGO53095.1 - 2.5e-45 153.1 0.8 7.1e-45 151.6 0.8 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGO53095.1 - 2e-05 24.3 0.7 2e-05 24.3 0.7 1.9 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGO53095.1 - 0.00023 20.9 3.4 0.0039 17.0 0.2 2.9 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III WD40 PF00400.32 EGO53096.1 - 3e-12 46.8 0.9 0.047 14.6 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Sel1 PF08238.12 EGO53097.1 - 2.7e-43 145.4 34.6 3.9e-07 30.5 0.2 11.8 11 1 1 12 12 12 8 Sel1 repeat GRP PF07172.11 EGO53097.1 - 0.00045 20.8 1.1 0.0012 19.5 1.1 1.7 1 0 0 1 1 1 1 Glycine rich protein family TPR_17 PF13431.6 EGO53097.1 - 0.077 13.4 1.6 12 6.6 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat OPA3 PF07047.12 EGO53097.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) TPR_7 PF13176.6 EGO53097.1 - 2.9 8.1 13.4 6.2 7.1 0.1 6.2 6 1 0 6 6 6 0 Tetratricopeptide repeat tRNA-synt_2c PF01411.19 EGO53101.1 - 2.1e-214 713.1 1.1 4.5e-214 712.0 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EGO53101.1 - 2e-18 66.2 0.3 4.5e-18 65.1 0.3 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EGO53101.1 - 1.2e-14 54.9 2.3 1.2e-14 54.9 2.3 2.3 2 0 0 2 2 2 1 DHHA1 domain Methyltransf_28 PF02636.17 EGO53102.1 - 1.3e-36 126.6 0.0 3e-36 125.4 0.0 1.6 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 EGO53102.1 - 0.00013 21.8 0.1 0.0031 17.4 0.0 2.5 2 1 0 2 2 2 1 PRMT5 arginine-N-methyltransferase PALP PF00291.25 EGO53103.1 - 1.6e-63 214.9 0.9 2.1e-63 214.5 0.9 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IpgD PF05925.12 EGO53103.1 - 0.072 11.6 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD TFIIS_M PF07500.14 EGO53105.1 - 1.1e-24 87.0 2.3 1.1e-24 87.0 2.3 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EGO53105.1 - 7e-19 67.4 6.1 1.9e-18 66.0 6.1 1.8 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EGO53105.1 - 2e-11 43.7 3.6 2.1e-11 43.7 1.2 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain MFS_1 PF07690.16 EGO53106.1 - 1.3e-36 126.3 48.5 3.8e-36 124.7 46.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO53106.1 - 4.6e-05 22.0 20.4 0.00019 20.0 20.3 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1385 PF07136.11 EGO53106.1 - 0.042 13.1 0.1 0.092 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) DUF4448 PF14610.6 EGO53107.1 - 9.9e-39 133.1 0.0 1.3e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.9 EGO53107.1 - 0.068 13.9 0.1 0.18 12.6 0.1 1.7 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family 2OG-FeII_Oxy PF03171.20 EGO53108.1 - 0.011 16.2 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FRG1 PF06229.12 EGO53109.1 - 2.4e-52 177.4 0.4 3e-52 177.1 0.4 1.0 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 EGO53109.1 - 0.084 13.1 0.0 0.2 11.9 0.0 1.6 1 1 0 1 1 1 0 Fascin domain SRF-TF PF00319.18 EGO53110.1 - 7.3e-24 83.0 0.2 1.1e-23 82.4 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3591 PF12157.8 EGO53112.1 - 2.6e-166 553.7 0.0 3.4e-166 553.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 EGO53112.1 - 0.018 14.9 0.6 0.043 13.7 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 EGO53112.1 - 0.17 12.0 0.2 0.3 11.2 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle D-ser_dehydrat PF14031.6 EGO53113.1 - 1.4e-23 83.3 0.0 9.7e-23 80.7 0.0 2.2 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EGO53113.1 - 1.3e-10 41.3 0.0 2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Actin PF00022.19 EGO53114.1 - 4.2e-152 506.5 0.0 4.8e-152 506.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGO53114.1 - 1.1e-06 27.7 0.0 0.0076 15.1 0.0 2.5 3 0 0 3 3 3 2 MreB/Mbl protein Vps8 PF12816.7 EGO53115.1 - 6.1e-78 260.9 0.0 1.5e-77 259.6 0.0 1.7 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EGO53115.1 - 1.3e-08 34.8 0.7 0.00044 20.1 0.1 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_5 PF14634.6 EGO53115.1 - 0.058 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 EGO53115.1 - 0.076 12.8 0.8 0.21 11.3 0.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 EGO53115.1 - 0.13 12.6 0.1 0.35 11.2 0.1 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 EGO53115.1 - 0.15 12.1 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 EGO53115.1 - 0.2 12.0 0.1 0.47 10.8 0.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 EGO53115.1 - 2.2 8.4 5.0 0.43 10.7 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger DUF3752 PF12572.8 EGO53117.1 - 3.4e-49 167.3 8.4 3.4e-49 167.3 8.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) zf-RING_2 PF13639.6 EGO53118.1 - 3.4e-12 46.5 6.4 5.6e-12 45.8 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO53118.1 - 1.8e-08 34.0 6.3 3e-08 33.4 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGO53118.1 - 2.7e-08 33.4 0.7 4.7e-08 32.6 0.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGO53118.1 - 3.2e-08 33.3 3.8 5.2e-08 32.6 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGO53118.1 - 5.2e-07 29.9 8.7 1.9e-06 28.1 8.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGO53118.1 - 1.4e-06 28.1 3.6 2.3e-06 27.4 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGO53118.1 - 8.3e-05 22.5 4.4 0.00016 21.6 0.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGO53118.1 - 0.00079 19.2 2.4 0.0013 18.6 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGO53118.1 - 0.00086 19.3 2.3 0.002 18.2 2.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGO53118.1 - 0.01 15.6 6.5 0.022 14.6 6.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 EGO53118.1 - 0.023 14.6 1.1 0.023 14.6 1.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 EGO53118.1 - 0.034 14.0 4.1 0.075 12.9 4.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EGO53118.1 - 0.056 13.6 3.6 0.16 12.2 3.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 EGO53118.1 - 0.067 13.1 5.6 0.12 12.3 5.6 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 EGO53118.1 - 0.074 12.7 4.6 0.14 11.8 4.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EGO53118.1 - 0.32 11.2 4.3 0.74 10.0 4.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 EGO53118.1 - 0.33 11.1 5.4 0.25 11.5 3.4 1.9 2 1 0 2 2 2 0 RING-variant domain Raffinose_syn PF05691.12 EGO53119.1 - 7.2e-51 172.9 2.0 2e-42 145.0 0.0 2.1 1 1 1 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_31 PF01055.26 EGO53119.1 - 8.1e-05 22.0 0.5 0.00011 21.6 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.18 EGO53119.1 - 0.0071 15.3 0.5 0.0093 15.0 0.5 1.2 1 0 0 1 1 1 1 Melibiase Peptidase_M16 PF00675.20 EGO53120.1 - 3e-57 192.8 0.4 9.5e-57 191.2 0.5 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGO53120.1 - 2.6e-39 135.2 0.0 2.4e-37 128.7 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain M16C_assoc PF08367.11 EGO53120.1 - 0.0097 15.1 0.2 0.017 14.3 0.2 1.4 1 0 0 1 1 1 1 Peptidase M16C associated RbsD_FucU PF05025.13 EGO53120.1 - 0.029 14.8 0.8 0.13 12.7 0.3 2.2 2 1 0 2 2 2 0 RbsD / FucU transport protein family DUF1713 PF08213.11 EGO53121.1 - 7e-08 32.3 19.4 7e-08 32.3 19.4 2.1 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 EGO53121.1 - 0.013 16.2 0.4 0.036 14.8 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Thioredoxin_4 PF13462.6 EGO53122.1 - 3e-08 34.0 0.0 6.4e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EGO53122.1 - 0.054 13.3 2.3 0.92 9.3 0.3 2.6 1 1 0 2 2 2 0 DSBA-like thioredoxin domain NGP1NT PF08153.12 EGO53123.1 - 3.8e-49 166.2 0.7 7.3e-49 165.2 0.7 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EGO53123.1 - 2.8e-19 69.3 0.0 2.5e-15 56.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO53123.1 - 1.6e-06 27.7 0.1 2.2e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGO53123.1 - 4.1e-06 26.8 0.0 1.7e-05 24.8 0.0 2.0 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EGO53123.1 - 3.4e-05 24.0 0.6 0.12 12.4 0.0 3.6 2 1 1 3 3 3 1 Dynamin family Arf PF00025.21 EGO53123.1 - 0.0066 15.9 0.0 4.1 6.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGO53123.1 - 0.011 15.3 0.0 0.4 10.2 0.0 2.6 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain BUD22 PF09073.10 EGO53123.1 - 0.71 9.1 25.5 1.3 8.3 25.5 1.4 1 0 0 1 1 1 0 BUD22 ABC2_membrane PF01061.24 EGO53124.1 - 1.3e-38 132.5 23.5 1.3e-38 132.5 23.5 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EGO53124.1 - 3.4e-25 89.2 0.0 5.4e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGO53124.1 - 2.4e-07 30.2 23.7 2.4e-07 30.2 23.7 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGO53124.1 - 2.6e-05 24.2 0.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGO53124.1 - 0.0051 16.5 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGO53124.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 EGO53124.1 - 0.018 14.6 0.1 0.043 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EGO53124.1 - 0.027 13.9 0.0 0.55 9.6 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EGO53124.1 - 0.035 14.6 0.0 0.099 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGO53124.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EGO53124.1 - 0.095 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGO53124.1 - 0.096 13.2 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.21 EGO53125.1 - 2.9e-36 125.4 0.0 3.7e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGO53125.1 - 4.1e-05 22.3 0.0 5.8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGO53125.1 - 0.0001 21.4 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_MocR PF12897.7 EGO53125.1 - 0.093 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Hexokinase_2 PF03727.16 EGO53126.1 - 1.6e-81 273.3 0.0 2.1e-81 272.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EGO53126.1 - 7.1e-72 241.5 0.0 1.5e-71 240.5 0.0 1.5 2 0 0 2 2 2 1 Hexokinase FGGY_N PF00370.21 EGO53126.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Ribophorin_I PF04597.14 EGO53127.1 - 1.2e-153 512.5 0.1 1.4e-153 512.3 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I Pil1 PF13805.6 EGO53128.1 - 3.6e-111 370.9 4.1 5.4e-111 370.3 4.1 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 Seryl_tRNA_N PF02403.22 EGO53128.1 - 4.9 7.4 9.3 2.8 8.2 3.0 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CCDC53 PF10152.9 EGO53128.1 - 8.2 6.8 10.2 13 6.1 9.4 1.7 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex MCM PF00493.23 EGO53129.1 - 1.9e-101 337.9 0.0 3.1e-101 337.1 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGO53129.1 - 9.4e-40 135.4 0.9 1.9e-39 134.4 0.9 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGO53129.1 - 4.9e-30 103.8 2.3 1.2e-29 102.5 2.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGO53129.1 - 6e-18 65.4 0.0 2.1e-17 63.6 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGO53129.1 - 1.5e-05 24.4 0.0 0.00025 20.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGO53129.1 - 2.1e-05 24.6 0.1 8.9e-05 22.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGO53129.1 - 0.0031 17.4 0.0 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EGO53129.1 - 0.019 14.8 0.1 0.049 13.5 0.1 1.6 1 0 0 1 1 1 0 AAA lid domain Clat_adaptor_s PF01217.20 EGO53130.1 - 9e-14 51.6 0.0 2.5e-12 46.9 0.1 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Sua5_yciO_yrdC PF01300.18 EGO53131.1 - 9.8e-52 175.0 0.0 1.4e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EGO53131.1 - 3.3e-32 111.8 0.0 6.2e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Pkinase PF00069.25 EGO53132.1 - 1.4e-53 182.0 0.0 1.8e-53 181.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO53132.1 - 3.4e-41 141.2 0.0 4.7e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO53132.1 - 0.0051 16.2 0.0 0.073 12.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGO53132.1 - 0.011 14.8 0.1 0.38 9.7 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EGO53132.1 - 0.023 13.5 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGO53132.1 - 0.066 13.1 0.0 0.63 9.9 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGO53132.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAD_binding_3 PF01494.19 EGO53134.1 - 4e-25 88.8 0.0 1.6e-23 83.5 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGO53134.1 - 3.9e-06 26.7 0.0 0.08 12.5 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 EGO53134.1 - 4.3e-05 22.7 0.0 6.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 EGO53134.1 - 5.7e-05 22.3 0.2 0.014 14.4 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EGO53134.1 - 0.00029 20.2 0.0 0.012 14.9 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO53134.1 - 0.012 14.9 0.0 0.23 10.7 0.0 2.1 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 EGO53134.1 - 0.012 15.5 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EGO53134.1 - 0.039 12.8 0.0 2.3 7.0 0.0 2.8 2 1 1 3 3 3 0 Tryptophan halogenase NAD_binding_8 PF13450.6 EGO53134.1 - 0.092 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EGO53134.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Complex1_49kDa PF00346.19 EGO53136.1 - 5.3e-123 409.4 0.0 7.4e-123 408.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EGO53136.1 - 0.0049 15.8 0.0 0.0067 15.4 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase RNA_pol_A_bac PF01000.26 EGO53137.1 - 5.6e-27 94.3 0.0 5e-26 91.3 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGO53137.1 - 2.1e-17 62.3 0.0 3.2e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.21 EGO53138.1 - 5.8e-61 206.0 0.0 8.3e-61 205.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EGO53138.1 - 5.5e-29 100.2 0.2 8.6e-29 99.5 0.2 1.3 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 EGO53138.1 - 4.5e-05 24.0 0.5 0.00021 21.8 0.0 2.3 3 0 0 3 3 3 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Ecm33 PF12454.8 EGO53138.1 - 0.034 14.3 2.9 0.071 13.3 2.9 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Telomere_reg-2 PF10193.9 EGO53139.1 - 2e-38 131.2 0.0 6.8e-38 129.5 0.0 2.0 1 0 0 1 1 1 1 Telomere length regulation protein COX17 PF05051.13 EGO53140.1 - 1.5e-20 73.3 7.8 1.8e-20 73.0 7.8 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) TonB_N PF16031.5 EGO53140.1 - 0.012 16.1 0.1 0.014 15.9 0.1 1.1 1 0 0 1 1 1 0 TonB polyproline region DegT_DnrJ_EryC1 PF01041.17 EGO53141.1 - 7.8e-05 22.1 2.2 9.8e-05 21.8 2.2 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Atg14 PF10186.9 EGO53141.1 - 0.0066 15.6 5.2 0.0073 15.4 5.2 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4085 PF13315.6 EGO53141.1 - 0.013 15.1 0.6 0.021 14.4 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4085) FUSC-like PF12805.7 EGO53141.1 - 0.023 13.8 3.0 0.027 13.6 3.0 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS APC1_C PF18122.1 EGO53141.1 - 0.063 13.2 0.9 0.076 13.0 0.9 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain MDM10 PF12519.8 EGO53141.1 - 0.072 12.0 1.4 0.087 11.7 1.4 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Sec23_helical PF04815.15 EGO53141.1 - 0.14 12.0 3.0 6.3 6.7 0.3 2.4 1 1 1 2 2 2 0 Sec23/Sec24 helical domain Exonuc_VII_L PF02601.15 EGO53141.1 - 0.27 10.8 5.2 0.29 10.7 5.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 EGO53141.1 - 0.55 10.6 7.6 1.2 9.4 7.6 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Med4 PF10018.9 EGO53141.1 - 0.73 9.5 7.3 0.12 12.0 2.0 2.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 G-patch PF01585.23 EGO53142.1 - 8.5e-05 22.4 0.0 0.00025 20.9 0.0 1.9 1 0 0 1 1 1 1 G-patch domain TraF PF13728.6 EGO53142.1 - 0.0079 16.0 5.3 0.0079 16.0 5.3 3.4 1 1 1 2 2 2 1 F plasmid transfer operon protein G-patch_2 PF12656.7 EGO53142.1 - 0.021 14.9 0.0 0.021 14.9 0.0 5.1 3 1 1 4 4 4 0 G-patch domain DUF936 PF06075.12 EGO53142.1 - 0.023 13.7 35.4 0.027 13.4 35.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Red1 PF07964.11 EGO53142.1 - 0.054 11.7 51.9 0.076 11.2 51.9 1.2 1 0 0 1 1 1 0 Rec10 / Red1 CDC27 PF09507.10 EGO53142.1 - 0.32 10.3 62.9 0.54 9.6 62.9 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Macoilin PF09726.9 EGO53142.1 - 0.98 7.9 33.0 1.4 7.4 33.0 1.3 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 EGO53142.1 - 1.8 5.6 31.0 2.2 5.3 31.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mitofilin PF09731.9 EGO53142.1 - 6.3 5.5 49.9 9.2 5.0 49.9 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Macoilin PF09726.9 EGO53143.1 - 7.9 4.9 8.7 13 4.2 8.7 1.3 1 0 0 1 1 1 0 Macoilin family Zn_clus PF00172.18 EGO53146.1 - 0.00033 20.7 13.0 0.00052 20.1 13.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGO53146.1 - 0.011 14.8 0.0 0.026 13.6 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain MerR-DNA-bind PF09278.11 EGO53146.1 - 0.19 12.3 0.1 0.52 10.9 0.1 1.7 1 0 0 1 1 1 0 MerR, DNA binding RhoGAP PF00620.27 EGO53147.1 - 9.7e-44 148.9 0.0 2.2e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EGO53147.1 - 2.4e-14 53.7 0.0 4.8e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EGO53147.1 - 0.024 14.9 0.0 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3450 PF11932.8 EGO53147.1 - 0.57 9.4 4.2 1.2 8.4 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MFS_1 PF07690.16 EGO53148.1 - 1.9e-31 109.3 61.7 3e-27 95.5 36.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO53148.1 - 5e-10 38.8 8.3 5e-10 38.8 8.3 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EGO53148.1 - 0.00018 20.1 2.7 0.0017 16.9 1.4 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) PITH PF06201.13 EGO53150.1 - 6.9e-39 133.5 0.0 1e-38 132.9 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 EGO53150.1 - 4.5e-08 33.0 0.0 8.8e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.16 EGO53150.1 - 0.031 14.0 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 Presenilin PF01080.17 EGO53151.1 - 0.37 9.5 2.8 0.51 9.1 2.8 1.1 1 0 0 1 1 1 0 Presenilin BASP1 PF05466.12 EGO53151.1 - 4.8 7.1 10.2 7.1 6.6 10.2 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) PRA1 PF03208.19 EGO53153.1 - 6.7e-39 132.8 0.4 8.6e-39 132.4 0.4 1.1 1 0 0 1 1 1 1 PRA1 family protein VirB3 PF05101.13 EGO53153.1 - 2 8.7 8.1 0.16 12.2 1.8 2.0 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein GH131_N PF18271.1 EGO53155.1 - 3.5e-80 269.4 0.6 4.1e-80 269.2 0.6 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain FluMu_N PF17891.1 EGO53155.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain DPPIV_N PF00930.21 EGO53156.1 - 2.5e-114 381.8 1.5 3.4e-114 381.3 1.5 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EGO53156.1 - 6.8e-59 198.9 2.1 1.2e-58 198.1 2.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EGO53156.1 - 8.5e-08 32.1 1.7 2.2e-06 27.5 0.6 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EGO53156.1 - 6e-05 23.7 3.6 0.019 15.6 0.3 2.8 2 1 1 3 3 3 2 Alpha/beta hydrolase family DUF4988 PF16378.5 EGO53156.1 - 0.0018 18.0 0.1 0.0055 16.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function DLH PF01738.18 EGO53156.1 - 0.072 12.6 0.0 0.37 10.3 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EGO53156.1 - 0.081 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 EGO53156.1 - 0.089 11.3 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Mitovir_RNA_pol PF05919.11 EGO53156.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Abhydrolase_2 PF02230.16 EGO53156.1 - 0.17 11.7 0.0 9.6 5.9 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase ATP-synt_ab PF00006.25 EGO53157.1 - 1.2e-72 244.0 0.0 2.2e-72 243.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EGO53157.1 - 2.2e-48 163.7 0.4 3.8e-48 163.0 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EGO53157.1 - 3.5e-15 56.3 2.8 8.4e-15 55.0 2.8 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Carb_kinase PF01256.17 EGO53158.1 - 1.2e-54 185.4 0.1 1.7e-54 184.9 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 EGO53158.1 - 6.7e-05 22.4 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 EGO53158.1 - 0.00051 19.5 0.3 0.0017 17.8 0.3 1.8 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PEP-utilizers PF00391.23 EGO53158.1 - 0.14 11.9 1.6 8.2 6.2 0.0 2.7 3 0 0 3 3 3 0 PEP-utilising enzyme, mobile domain QRPTase_C PF01729.19 EGO53160.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Methyltr_RsmB-F PF01189.17 EGO53161.1 - 1.8e-77 259.5 0.0 5.3e-77 258.0 0.0 1.8 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EGO53161.1 - 9.2e-08 32.5 0.0 3.7e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF DUF2431 PF10354.9 EGO53161.1 - 0.034 14.4 0.0 0.092 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Methyltransf_25 PF13649.6 EGO53161.1 - 0.054 14.2 0.0 0.17 12.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Clathrin PF00637.20 EGO53162.1 - 2.1e-199 653.4 47.8 6.9e-33 113.5 1.9 8.3 9 1 1 10 10 10 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 EGO53162.1 - 1.2e-35 121.2 0.5 9.5e-35 118.3 0.5 2.7 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.20 EGO53162.1 - 6.3e-35 117.8 0.6 2.1e-07 30.9 0.1 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat TPR_14 PF13428.6 EGO53162.1 - 1.4e-06 28.6 7.3 10 7.2 0.0 8.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO53162.1 - 0.0027 17.6 8.1 22 5.4 0.2 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat VapB_antitoxin PF09957.9 EGO53162.1 - 0.014 15.3 0.1 0.33 10.9 0.0 3.0 2 0 0 2 2 2 0 Bacterial antitoxin of type II TA system, VapB Clathrin-link PF09268.10 EGO53162.1 - 0.023 14.1 1.8 0.25 10.8 1.8 2.6 1 1 0 1 1 1 0 Clathrin, heavy-chain linker Rop PF01815.16 EGO53162.1 - 0.036 14.0 0.2 0.16 11.8 0.2 2.2 1 0 0 1 1 1 0 Rop protein TPR_1 PF00515.28 EGO53162.1 - 0.039 13.8 5.4 23 5.0 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 EGO53162.1 - 0.08 13.2 1.7 48 4.5 0.0 5.2 4 0 0 4 4 4 0 PPR repeat TPR_8 PF13181.6 EGO53162.1 - 0.084 13.1 6.8 9.8 6.7 0.0 6.2 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGO53162.1 - 9.1 6.9 6.9 34 5.0 0.1 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Ribosomal_L5_C PF00673.21 EGO53163.1 - 7e-22 77.4 0.0 1e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EGO53163.1 - 2.8e-21 75.6 0.0 8.8e-21 74.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 EGO53164.1 - 3.6e-19 68.2 0.0 5.3e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain MPC PF03650.13 EGO53165.1 - 7.7e-36 122.6 0.0 8.8e-36 122.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 EGO53165.1 - 0.021 14.9 0.7 0.027 14.5 0.7 1.2 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange DUF599 PF04654.12 EGO53165.1 - 0.028 13.8 0.1 0.032 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF599 CPSase_L_D2 PF02786.17 EGO53167.1 - 4.3e-81 271.4 0.3 7.2e-81 270.7 0.3 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EGO53167.1 - 1.7e-69 233.6 0.0 3e-69 232.7 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EGO53167.1 - 1.3e-38 131.9 0.0 2.6e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGO53167.1 - 2.9e-30 104.5 0.0 6.6e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EGO53167.1 - 7.3e-28 97.9 0.0 1.5e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EGO53167.1 - 5e-19 67.9 2.2 8.6e-19 67.1 0.8 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGO53167.1 - 6.2e-10 39.0 0.0 1.3e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EGO53167.1 - 1.8e-09 37.3 0.5 7.2e-06 25.7 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 EGO53167.1 - 1.4e-07 31.3 0.0 2.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EGO53167.1 - 2.3e-05 24.5 0.0 5.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 EGO53167.1 - 2.9e-05 23.4 0.1 0.17 11.1 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 EGO53167.1 - 0.00037 20.1 0.0 0.0014 18.3 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 EGO53167.1 - 0.0067 16.0 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EGO53167.1 - 0.012 16.4 0.3 2.5 8.8 0.0 3.2 3 0 0 3 3 2 0 HlyD family secretion protein ATPgrasp_ST PF14397.6 EGO53167.1 - 0.018 14.3 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 EGO53167.1 - 0.042 13.8 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_YheCD PF14398.6 EGO53167.1 - 0.045 13.0 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 YheC/D like ATP-grasp GARS_A PF01071.19 EGO53167.1 - 0.086 12.6 0.0 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain QRPTase_N PF02749.16 EGO53167.1 - 0.14 12.2 0.1 2.7 8.1 0.0 3.0 2 1 1 3 3 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain DUF1640 PF07798.11 EGO53168.1 - 3.6e-57 193.2 10.4 4.3e-57 193.0 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GNAT_acetyltr_2 PF13718.6 EGO53168.1 - 0.014 14.8 1.0 0.039 13.3 0.1 1.9 1 1 1 2 2 2 0 GNAT acetyltransferase 2 Lzipper-MIP1 PF14389.6 EGO53168.1 - 0.11 12.8 4.2 3.3 8.1 4.2 2.7 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 HU-CCDC81_bac_2 PF18175.1 EGO53168.1 - 0.25 11.2 2.9 0.59 10.0 1.1 2.2 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 BST2 PF16716.5 EGO53168.1 - 4.6 7.9 13.3 1.9 9.1 1.2 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Uso1_p115_C PF04871.13 EGO53168.1 - 7.2 7.0 12.2 6 7.3 2.2 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Methyltransf_11 PF08241.12 EGO53170.1 - 1.2e-22 80.4 0.0 2.2e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO53170.1 - 4.1e-22 78.7 0.0 8.1e-21 74.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO53170.1 - 5.4e-17 62.0 0.0 8e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO53170.1 - 4.4e-14 52.4 0.0 1.8e-13 50.4 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGO53170.1 - 2.7e-13 50.1 0.0 4.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO53170.1 - 1.5e-12 48.1 0.0 3.2e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGO53170.1 - 1.3e-08 34.5 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 EGO53170.1 - 4.3e-07 29.7 0.0 7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 EGO53170.1 - 4.7e-06 26.2 0.1 8.6e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGO53170.1 - 0.00016 21.2 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EGO53170.1 - 0.00036 19.9 0.0 0.0006 19.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_8 PF05148.15 EGO53170.1 - 0.00036 20.4 0.0 0.013 15.3 0.0 2.8 2 1 0 2 2 2 1 Hypothetical methyltransferase TehB PF03848.14 EGO53170.1 - 0.00059 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 EGO53170.1 - 0.0012 18.4 0.0 0.0029 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 EGO53170.1 - 0.0026 17.5 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NitrOD2 PF18550.1 EGO53170.1 - 0.003 17.7 0.2 0.038 14.1 0.0 2.2 2 0 0 2 2 2 1 Nitrososphaera output domain 2 Methyltransf_32 PF13679.6 EGO53170.1 - 0.0038 17.2 0.0 0.0061 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EGO53170.1 - 0.028 13.5 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.11 EGO53170.1 - 0.074 12.0 0.1 0.19 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) DOT1 PF08123.13 EGO53170.1 - 0.19 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 DCR PF14047.6 EGO53172.1 - 0.012 15.8 20.6 13 6.1 0.1 5.4 4 1 1 5 5 5 0 Dppa2/4 conserved region zf-DNL PF05180.12 EGO53173.1 - 7.9e-28 96.2 0.9 1.5e-27 95.3 0.9 1.5 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.13 EGO53173.1 - 0.041 13.9 1.7 0.12 12.5 0.5 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.6 EGO53173.1 - 0.082 12.8 1.0 1.1 9.2 0.2 2.8 2 1 1 3 3 3 0 zinc-ribbon domain Cullin PF00888.22 EGO53174.1 - 3e-197 657.1 3.9 3.7e-197 656.8 3.9 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGO53174.1 - 3.2e-25 87.9 0.2 1.1e-24 86.2 0.2 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain DprA_WH PF17782.1 EGO53174.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 DprA winged helix domain DNA_pol_phi PF04931.13 EGO53175.1 - 3.4e-190 633.9 27.3 3.4e-190 633.9 27.3 2.5 2 1 0 2 2 2 1 DNA polymerase phi RTP1_C1 PF10363.9 EGO53175.1 - 0.027 14.6 0.0 0.63 10.2 0.0 2.9 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Vps35 PF03635.17 EGO53175.1 - 0.037 12.5 8.3 0.51 8.8 1.5 2.6 3 0 0 3 3 3 0 Vacuolar protein sorting-associated protein 35 DUF29 PF01724.16 EGO53175.1 - 0.11 12.8 0.1 0.11 12.8 0.1 3.5 5 0 0 5 5 5 0 Domain of unknown function DUF29 XPC-binding PF09280.11 EGO53175.1 - 0.16 11.7 0.0 0.89 9.3 0.0 2.3 1 0 0 1 1 1 0 XPC-binding domain Rhodanese PF00581.20 EGO53176.1 - 2.8e-12 47.1 0.0 7e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain CwfJ_C_1 PF04677.15 EGO53177.1 - 6.4e-26 90.6 0.0 1.1e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EGO53177.1 - 3.6e-13 50.2 0.2 7.7e-13 49.2 0.2 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 YukC PF10140.9 EGO53177.1 - 0.24 10.2 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DRIM PF07539.12 EGO53178.1 - 3.1e-189 630.3 0.7 1.5e-187 624.8 0.0 3.5 3 1 0 3 3 3 1 Down-regulated in metastasis SAGA-Tad1 PF12767.7 EGO53178.1 - 0.049 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Proteasome PF00227.26 EGO53179.1 - 6.7e-47 159.4 0.2 8e-32 110.3 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EGO53179.1 - 9.2e-13 47.6 0.9 1.2e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DnaJ PF00226.31 EGO53181.1 - 1.4e-17 63.6 0.2 2.5e-17 62.7 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 EGO53181.1 - 0.098 13.0 0.5 0.098 13.0 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 EGO53181.1 - 3.2 7.9 13.8 0.34 11.0 0.7 2.6 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DnaJ PF00226.31 EGO53182.1 - 2.2e-10 40.5 0.6 5.8e-10 39.2 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain FYTT PF07078.11 EGO53182.1 - 0.0075 15.6 6.9 0.19 11.0 0.3 2.3 2 0 0 2 2 2 2 Forty-two-three protein DUF4228 PF14009.6 EGO53182.1 - 3.1 8.2 7.9 13 6.1 4.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4228) Peptidase_S49_N PF08496.10 EGO53182.1 - 6.6 6.8 10.0 5.4 7.1 4.5 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ndc1_Nup PF09531.10 EGO53182.1 - 6.7 5.3 4.8 8.9 4.9 0.9 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup PRIMA1 PF16101.5 EGO53182.1 - 9.8 6.2 9.1 2.6 8.1 4.5 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 RNA_ligase PF09414.10 EGO53183.1 - 5.2e-29 101.6 0.0 8.9e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 RNA ligase AP_endonuc_2 PF01261.24 EGO53185.1 - 0.13 11.7 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel zf-C2H2 PF00096.26 EGO53186.1 - 0.0014 19.0 2.4 0.0014 19.0 2.4 3.6 3 1 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 EGO53186.1 - 0.0096 16.5 0.1 0.032 14.9 0.1 1.9 1 0 0 1 1 1 1 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 EGO53186.1 - 0.067 13.2 0.2 0.067 13.2 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EGO53186.1 - 2.2 9.4 9.6 0.47 11.4 1.9 3.2 2 1 0 2 2 2 0 C2H2-type zinc finger Ank_2 PF12796.7 EGO53187.1 - 1.4e-12 48.0 0.0 2.5e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO53187.1 - 3.9e-09 36.0 5.7 0.0006 20.1 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EGO53187.1 - 1.2e-08 35.3 0.7 0.0095 16.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO53187.1 - 4.7e-08 33.1 1.1 0.012 15.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGO53187.1 - 9.4e-05 22.7 3.9 0.16 12.5 0.4 3.7 3 1 1 4 4 4 2 Ankyrin repeat Erv26 PF04148.13 EGO53187.1 - 0.0055 16.6 0.0 0.0055 16.6 0.0 2.3 3 0 0 3 3 3 1 Transmembrane adaptor Erv26 Herpes_LAMP2 PF06126.11 EGO53187.1 - 0.0082 14.8 0.2 0.012 14.2 0.2 1.2 1 0 0 1 1 1 1 Herpesvirus Latent membrane protein 2 DUF3446 PF11928.8 EGO53187.1 - 0.31 11.4 9.2 0.057 13.7 4.2 2.0 2 0 0 2 2 2 0 Early growth response N-terminal domain AMP-binding PF00501.28 EGO53188.1 - 5.8e-69 232.7 0.0 1e-67 228.6 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO53188.1 - 2.8e-14 53.8 1.1 5.3e-14 53.0 0.2 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4360 PF14273.6 EGO53190.1 - 1.2e-67 227.2 3.2 1.4e-67 227.1 3.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Citrate_synt PF00285.21 EGO53191.1 - 1.7e-102 343.2 0.0 2e-102 343.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ICL PF00463.21 EGO53192.1 - 3.1e-196 652.9 0.4 3.6e-196 652.7 0.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EGO53192.1 - 1.8e-10 40.7 0.0 3.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Gln-synt_C PF00120.24 EGO53193.1 - 5.2e-85 285.5 0.0 9.3e-85 284.7 0.0 1.4 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain Alpha-amylase PF00128.24 EGO53194.1 - 1.2e-21 77.7 0.6 1.2e-21 77.7 0.6 2.9 3 1 0 3 3 3 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 EGO53194.1 - 6.1e-18 65.4 0.0 1.1e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EGO53194.1 - 7.6e-06 25.6 0.0 2.5e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGO53194.1 - 0.0012 18.9 0.0 0.0031 17.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EGO53194.1 - 0.017 15.5 0.0 0.049 14.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain WD40 PF00400.32 EGO53195.1 - 1.2e-20 73.4 3.0 0.0012 19.6 0.0 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO53195.1 - 2.3e-09 37.4 0.0 0.033 14.5 0.0 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO53195.1 - 0.00047 19.2 0.1 1.4 7.8 0.0 3.5 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ADH_N PF08240.12 EGO53196.1 - 2.1e-31 108.1 0.7 3.8e-31 107.2 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO53196.1 - 2.5e-25 89.0 0.4 4.1e-25 88.3 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO53196.1 - 0.00073 20.6 0.1 0.0013 19.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGO53196.1 - 0.034 13.4 0.3 0.066 12.5 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EGO53196.1 - 0.049 13.1 0.6 0.095 12.2 0.6 1.5 1 0 0 1 1 1 0 short chain dehydrogenase GDC-P PF02347.16 EGO53197.1 - 1e-173 578.1 0.0 1.2e-159 531.8 0.0 2.4 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EGO53197.1 - 2.1e-06 27.0 0.0 0.00011 21.3 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGO53197.1 - 5.1e-06 26.0 0.0 9.5e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Tom5 PF10642.9 EGO53198.1 - 4.6e-22 77.8 0.8 5e-22 77.7 0.8 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.6 EGO53199.1 - 8.3e-40 136.1 0.2 8.3e-40 136.1 0.2 2.7 3 0 0 3 3 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 EGO53199.1 - 8e-14 50.9 8.4 1.7e-13 49.9 8.4 1.6 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Nucleoporin_FG PF13634.6 EGO53199.1 - 0.00011 23.0 15.3 0.00017 22.4 15.3 1.2 1 0 0 1 1 1 1 Nucleoporin FG repeat region Adhesin_P1_N PF18652.1 EGO53199.1 - 0.00062 19.7 3.6 0.0011 18.9 1.5 2.4 2 0 0 2 2 2 1 Adhesin P1 N-terminal domain Metal_resist PF13801.6 EGO53199.1 - 0.005 17.0 0.4 0.005 17.0 0.4 2.2 3 0 0 3 3 3 1 Heavy-metal resistance V-SNARE_C PF12352.8 EGO53199.1 - 0.0054 17.0 0.7 1.7 9.0 0.0 2.6 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DivIVA PF05103.13 EGO53199.1 - 0.018 15.1 3.1 0.018 15.1 3.1 2.1 2 1 0 2 2 2 0 DivIVA protein FUSC PF04632.12 EGO53199.1 - 0.052 12.1 1.8 0.08 11.5 1.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family EzrA PF06160.12 EGO53199.1 - 0.095 10.9 9.5 0.29 9.3 1.6 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Nbl1_Borealin_N PF10444.9 EGO53199.1 - 0.11 12.1 2.3 0.24 11.1 0.3 2.3 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Spc24 PF08286.11 EGO53199.1 - 0.14 12.4 3.8 9.4 6.5 1.2 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 GAPES3 PF17154.4 EGO53199.1 - 0.27 11.2 1.9 16 5.5 0.1 2.9 3 0 0 3 3 3 0 Gammaproteobacterial periplasmic sensor domain bZIP_1 PF00170.21 EGO53199.1 - 0.81 9.8 8.4 2.6 8.2 0.5 3.5 3 1 0 3 3 3 0 bZIP transcription factor Laminin_II PF06009.12 EGO53199.1 - 1.2 9.2 7.0 7.4 6.6 1.7 2.3 2 0 0 2 2 2 0 Laminin Domain II Remorin_C PF03763.13 EGO53199.1 - 5 7.0 9.5 0.46 10.4 2.1 2.7 2 1 0 3 3 3 0 Remorin, C-terminal region Bap31_Bap29_C PF18035.1 EGO53199.1 - 5.3 7.1 9.9 0.39 10.8 3.7 2.2 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Seryl_tRNA_N PF02403.22 EGO53199.1 - 8.9 6.6 11.7 1.1 9.5 1.5 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CHCH PF06747.13 EGO53200.1 - 2.9e-10 40.0 15.8 8.4e-09 35.3 5.2 2.6 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 EGO53200.1 - 1.3e-05 25.1 6.0 0.00083 19.3 2.2 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EGO53200.1 - 0.00019 21.4 10.8 0.01 15.8 1.0 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like RS4NT PF08071.12 EGO53200.1 - 0.018 15.1 0.8 0.046 13.8 0.2 1.9 2 0 0 2 2 2 0 RS4NT (NUC023) domain Pet191_N PF10203.9 EGO53200.1 - 0.34 11.3 6.1 8.3 6.8 0.0 2.8 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 CAP PF00188.26 EGO53203.1 - 3e-13 50.7 5.8 4.8e-13 50.1 5.8 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TRAM_LAG1_CLN8 PF03798.16 EGO53204.1 - 1.3e-50 171.9 18.7 2.1e-50 171.2 18.7 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 EGO53204.1 - 4.3e-17 61.5 0.2 4.3e-17 61.5 0.2 2.7 3 0 0 3 3 3 1 TRAM1-like protein RRM_1 PF00076.22 EGO53206.1 - 1.1e-15 57.2 0.0 5.7e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO53206.1 - 0.00091 19.3 0.1 0.0029 17.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif WD40 PF00400.32 EGO53207.1 - 1.6e-06 28.7 0.0 0.015 16.1 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO53207.1 - 0.0028 17.9 0.0 0.063 13.6 0.0 2.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGO53207.1 - 0.038 14.0 0.0 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EGO53207.1 - 0.047 12.7 0.2 0.24 10.3 0.1 1.8 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 EGO53207.1 - 0.21 9.5 0.0 0.3 9.0 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Septin PF00735.18 EGO53209.1 - 6.5e-108 360.3 0.1 1.3e-107 359.3 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EGO53209.1 - 1e-05 25.6 0.0 2.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGO53209.1 - 0.00046 20.3 3.3 0.26 11.3 0.0 3.1 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EGO53209.1 - 0.021 14.7 0.4 0.021 14.7 0.4 2.4 3 1 0 3 3 3 0 RsgA GTPase AAA_33 PF13671.6 EGO53209.1 - 0.046 13.9 0.4 0.097 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 EGO53209.1 - 0.061 12.6 0.1 0.17 11.2 0.1 1.7 1 1 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.27 EGO53209.1 - 0.09 12.3 0.5 0.47 10.0 0.1 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 EGO53209.1 - 0.12 12.8 4.2 18 5.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain EB1 PF03271.17 EGO53209.1 - 0.15 12.3 1.1 5.7 7.3 1.1 2.7 2 0 0 2 2 2 0 EB1-like C-terminal motif AAA_22 PF13401.6 EGO53209.1 - 0.19 12.0 1.5 0.34 11.2 0.1 2.1 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EGO53209.1 - 0.24 10.7 0.1 0.24 10.7 0.1 1.9 2 1 0 2 2 2 0 FtsK/SpoIIIE family Bax1-I PF01027.20 EGO53210.1 - 1e-50 172.5 23.9 1.2e-50 172.2 23.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Herpes_LMP2 PF07415.11 EGO53210.1 - 0.013 14.3 6.2 0.022 13.6 6.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein TMEM171 PF15471.6 EGO53210.1 - 2.3 7.1 4.0 0.93 8.4 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein family 171 DLIC PF05783.11 EGO53211.1 - 7.4e-23 81.1 2.4 3.7e-18 65.6 0.2 3.4 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) DUF4743 PF15916.5 EGO53211.1 - 0.11 12.4 0.2 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4743) DUF3695 PF12494.8 EGO53212.1 - 0.17 11.8 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3695) Thioredox_DsbH PF03190.15 EGO53214.1 - 2.7e-59 199.8 0.0 5.3e-59 198.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Glyco_hydro_9 PF00759.19 EGO53214.1 - 0.0044 16.5 0.1 0.0044 16.5 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 Sigma70_r4_2 PF08281.12 EGO53214.1 - 0.076 12.7 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 CDK2AP PF09806.9 EGO53214.1 - 0.64 10.1 10.4 1.2 9.2 10.4 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein TFIIA PF03153.13 EGO53214.1 - 3.9 7.4 18.1 5.7 6.8 18.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EGO53214.1 - 9.8 4.7 9.2 15 4.1 9.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3646 PF12362.8 EGO53215.1 - 0.039 14.3 2.3 0.062 13.6 2.3 1.2 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal Haem_bd PF14376.6 EGO53215.1 - 0.053 13.5 0.1 0.083 12.8 0.1 1.3 1 0 0 1 1 1 0 Haem-binding domain MFS_1 PF07690.16 EGO53216.1 - 1.2e-06 27.7 14.4 3.2e-05 23.0 12.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGO53216.1 - 0.38 9.0 4.2 0.87 7.8 0.1 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family UDPGT PF00201.18 EGO53217.1 - 8.5e-20 71.0 0.3 5e-19 68.5 0.3 1.9 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EGO53217.1 - 6.4e-08 32.7 0.0 9.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Lipase_GDSL_2 PF13472.6 EGO53218.1 - 5.6e-13 49.7 0.1 7.3e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGO53218.1 - 1e-06 28.9 0.0 1.8e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 EGO53218.1 - 0.085 12.5 0.1 0.24 11.0 0.1 1.7 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX ABC_membrane PF00664.23 EGO53219.1 - 1.6e-68 231.3 18.3 6.9e-38 130.9 7.7 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGO53219.1 - 2e-59 200.0 0.3 7.5e-32 110.7 0.0 3.3 2 1 1 3 3 3 3 ABC transporter SMC_N PF02463.19 EGO53219.1 - 1.8e-12 47.2 3.9 5.3e-05 22.7 0.1 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGO53219.1 - 3e-07 30.1 1.0 0.018 14.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGO53219.1 - 5.9e-07 30.0 1.9 0.0013 19.2 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 EGO53219.1 - 2.3e-06 27.6 0.1 0.019 14.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGO53219.1 - 4.2e-06 27.1 0.1 0.092 13.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EGO53219.1 - 7.2e-06 26.0 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 EGO53219.1 - 1.1e-05 24.5 0.0 0.00095 18.1 0.0 2.8 3 0 0 3 3 3 1 Predicted ATPase of the ABC class SbcCD_C PF13558.6 EGO53219.1 - 1.7e-05 25.0 2.8 0.45 10.8 0.3 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EGO53219.1 - 9.7e-05 22.3 0.1 0.18 11.6 0.0 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EGO53219.1 - 0.0002 20.7 0.0 0.016 14.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 EGO53219.1 - 0.00066 19.7 0.3 3.1 7.9 0.1 3.5 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EGO53219.1 - 0.0011 19.5 0.4 0.19 12.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGO53219.1 - 0.0012 18.6 2.9 2.6 7.7 0.1 4.1 3 2 0 3 3 3 2 AAA domain AAA_25 PF13481.6 EGO53219.1 - 0.0025 17.4 0.0 0.81 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EGO53219.1 - 0.004 17.3 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_5 PF07728.14 EGO53219.1 - 0.039 14.0 0.0 12 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGO53219.1 - 0.073 13.6 0.1 13 6.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 EGO53219.1 - 0.1 12.3 0.0 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 EGO53219.1 - 0.16 11.1 0.0 0.89 8.6 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 EGO53219.1 - 0.17 11.4 0.0 18 4.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Fungal_trans PF04082.18 EGO53220.1 - 4.1e-10 39.2 2.7 7.5e-10 38.3 0.1 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO53220.1 - 0.00067 19.7 5.3 0.0018 18.4 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.8 EGO53221.1 - 1.1e-07 32.0 3.7 1.7e-07 31.3 3.7 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGO53221.1 - 0.00012 22.4 0.9 0.00024 21.4 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGO53221.1 - 0.019 15.3 0.4 0.029 14.7 0.4 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EGO53221.1 - 0.082 13.4 0.8 0.14 12.7 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO53221.1 - 0.12 13.3 0.3 0.23 12.4 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger DUF2057 PF09829.9 EGO53221.1 - 0.27 11.4 1.3 0.71 10.0 1.3 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) zf-DBF PF07535.12 EGO53221.1 - 0.32 11.1 2.4 0.55 10.4 2.4 1.3 1 0 0 1 1 1 0 DBF zinc finger K_channel_TID PF07941.11 EGO53221.1 - 9.4 6.8 14.4 1.7 9.2 7.7 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF1691 PF07950.11 EGO53222.1 - 4e-40 136.8 7.9 3.6e-34 117.7 6.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Dioxygenase_C PF00775.21 EGO53226.1 - 5.4e-10 39.0 0.3 1.1e-09 37.9 0.3 1.6 1 1 0 1 1 1 1 Dioxygenase SpaA PF17802.1 EGO53226.1 - 0.035 14.4 0.0 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 Prealbumin-like fold domain Glyco_transf_28 PF03033.20 EGO53226.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Pex16 PF08610.10 EGO53227.1 - 2e-137 457.7 0.2 2.3e-137 457.5 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF4596 PF15363.6 EGO53227.1 - 2.7 8.3 5.8 0.49 10.7 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Pex14_N PF04695.13 EGO53228.1 - 0.011 16.4 0.3 0.021 15.5 0.2 1.6 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Flg_hook PF02120.16 EGO53228.1 - 0.038 13.9 1.1 0.038 13.9 1.1 1.7 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK SBF PF01758.16 EGO53229.1 - 1.4e-50 171.7 10.7 1.4e-50 171.7 10.7 2.1 2 1 0 2 2 2 1 Sodium Bile acid symporter family SBF_like PF13593.6 EGO53229.1 - 3.8e-07 29.7 16.7 4.8e-07 29.4 16.7 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) GMC_oxred_N PF00732.19 EGO53230.1 - 4.9e-76 255.9 0.0 6.7e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO53230.1 - 8.4e-35 120.4 0.0 1.7e-34 119.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EGO53230.1 - 0.00012 21.3 0.1 0.00021 20.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGO53230.1 - 0.0011 18.1 0.2 0.9 8.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EGO53230.1 - 0.0038 16.9 2.4 0.025 14.2 2.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO53230.1 - 0.0058 15.9 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO53230.1 - 0.012 14.9 0.0 0.028 13.7 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Snf7 PF03357.21 EGO53231.1 - 0.00036 20.2 26.2 0.00036 20.2 26.2 1.5 1 1 1 2 2 2 1 Snf7 NTP_transf_9 PF04248.12 EGO53232.1 - 2.6e-28 97.7 0.3 3.3e-28 97.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) GramPos_pilinD1 PF16555.5 EGO53232.1 - 0.21 11.8 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain bZIP_2 PF07716.15 EGO53233.1 - 2.6e-08 33.8 15.5 2.6e-08 33.8 15.5 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 EGO53233.1 - 0.00011 22.2 13.9 0.00023 21.2 13.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor Adaptin_binding PF10199.9 EGO53233.1 - 0.18 12.4 3.1 1.1 9.8 0.4 2.7 3 0 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 bZIP_Maf PF03131.17 EGO53233.1 - 0.68 10.5 11.1 1.8 9.1 11.1 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor DSHCT PF08148.12 EGO53234.1 - 9.7e-51 171.7 0.3 1.9e-50 170.7 0.3 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EGO53234.1 - 6.4e-39 132.8 0.2 2e-38 131.3 0.2 1.8 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 EGO53234.1 - 2.4e-28 99.8 0.0 4e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EGO53234.1 - 2.3e-18 66.6 0.0 5.4e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO53234.1 - 1.2e-06 28.8 0.0 5.8e-06 26.6 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO53234.1 - 1.5e-05 25.1 0.1 8.6e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Swi3 PF07962.12 EGO53235.1 - 6.9e-30 102.9 0.1 1.4e-29 101.8 0.1 1.5 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 NADH-u_ox-rdase PF10785.9 EGO53236.1 - 4.5e-29 100.9 0.2 6.9e-29 100.4 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 EGO53236.1 - 2.3e-24 85.2 0.0 3.3e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit ATP-grasp_3 PF02655.14 EGO53237.1 - 0.001 19.2 0.0 0.0037 17.3 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 EGO53237.1 - 0.082 12.5 0.1 0.38 10.3 0.1 2.0 1 1 0 1 1 1 0 ATP-grasp domain adh_short PF00106.25 EGO53239.1 - 3.1e-42 144.3 1.8 5e-42 143.6 1.8 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO53239.1 - 2.1e-40 138.7 1.5 4.6e-40 137.6 1.5 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO53239.1 - 9.3e-09 35.4 2.3 2.1e-08 34.3 0.4 2.1 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 EGO53239.1 - 0.0024 17.9 0.2 0.0048 16.9 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 EGO53239.1 - 0.012 15.9 0.3 0.025 14.9 0.3 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EGO53239.1 - 0.02 15.0 0.4 0.035 14.2 0.4 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EGO53239.1 - 0.067 13.1 0.4 0.23 11.3 0.2 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 EGO53239.1 - 0.073 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_7 PF13241.6 EGO53239.1 - 0.12 12.8 0.4 0.75 10.3 0.2 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding SWIRM PF04433.17 EGO53240.1 - 2.6e-14 53.3 0.1 2.5e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 SWIRM domain F-box-like PF12937.7 EGO53243.1 - 2.1e-09 37.2 0.4 3.7e-09 36.3 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO53243.1 - 7e-08 32.2 0.3 1.6e-07 31.1 0.3 1.6 1 0 0 1 1 1 1 F-box domain SGL PF08450.12 EGO53244.1 - 9.7e-25 87.6 0.4 1.5e-24 86.9 0.4 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EGO53244.1 - 4.3e-06 26.7 0.0 1.1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 EGO53244.1 - 4.8e-05 23.5 0.1 0.0029 17.8 0.0 3.2 3 0 0 3 3 3 1 Arylesterase NHL PF01436.21 EGO53244.1 - 0.00028 20.7 3.6 0.053 13.6 0.0 3.4 3 0 0 3 3 3 2 NHL repeat Glyco_hydro_61 PF03443.14 EGO53245.1 - 7.1e-59 199.2 0.0 9.7e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EGO53245.1 - 1.8e-08 34.2 15.9 1.8e-08 34.2 15.9 3.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Sugar_tr PF00083.24 EGO53246.1 - 3.3e-82 276.8 18.4 3.8e-82 276.6 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO53246.1 - 1.7e-16 60.1 34.5 5.6e-12 45.3 20.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily EBP PF05241.12 EGO53246.1 - 4.2 6.8 10.7 1.6 8.2 0.8 2.6 2 0 0 2 2 2 0 Emopamil binding protein Enolase_C PF00113.22 EGO53248.1 - 8.3e-116 386.4 0.0 1e-115 386.1 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EGO53248.1 - 3e-52 176.2 0.0 4.7e-52 175.6 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EGO53248.1 - 2.7e-06 27.1 0.0 4.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like HLH PF00010.26 EGO53249.1 - 2.6e-17 62.5 0.1 4.6e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.21 EGO53249.1 - 0.0056 16.7 0.4 0.02 15.0 0.2 1.9 2 0 0 2 2 2 1 bZIP transcription factor TSC22 PF01166.18 EGO53249.1 - 0.058 13.7 0.4 0.28 11.5 0.1 2.2 3 0 0 3 3 3 0 TSC-22/dip/bun family MAD PF05557.13 EGO53249.1 - 0.18 10.1 0.1 0.25 9.7 0.1 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein CDH-cyt PF16010.5 EGO53251.1 - 7.1e-48 162.7 4.0 8.2e-48 162.5 4.0 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase BPA_C PF18040.1 EGO53252.1 - 0.19 11.7 0.2 0.35 10.8 0.2 1.4 1 0 0 1 1 1 0 beta porphyranase A C-terminal ANAPC_CDC26 PF10471.9 EGO53254.1 - 0.0027 18.5 1.6 3.5 8.5 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex APC subunit CDC26 CXCR4_N PF12109.8 EGO53254.1 - 0.047 13.9 0.3 0.14 12.4 0.3 1.8 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal GRIP PF01465.20 EGO53257.1 - 1e-14 54.1 0.1 2.7e-14 52.8 0.1 1.8 1 0 0 1 1 1 1 GRIP domain MscS_porin PF12795.7 EGO53257.1 - 5.5e-07 29.4 110.0 0.0032 17.1 29.9 6.1 2 2 3 6 6 6 5 Mechanosensitive ion channel porin domain GAS PF13851.6 EGO53257.1 - 1.6e-05 24.4 102.0 0.00088 18.7 25.8 6.0 2 2 4 6 6 6 4 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EGO53257.1 - 6.6e-05 21.9 112.4 0.005 15.8 31.0 5.0 2 2 3 5 5 5 4 Spc7 kinetochore protein CALCOCO1 PF07888.11 EGO53257.1 - 0.0004 19.4 49.3 0.0004 19.4 49.3 3.6 2 1 1 3 3 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like UPF0242 PF06785.11 EGO53257.1 - 0.0025 18.0 31.6 0.0025 18.0 31.6 5.7 2 2 3 5 5 5 2 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 EGO53257.1 - 0.0026 17.8 18.3 0.0026 17.8 18.3 8.3 3 2 6 9 9 7 1 Designed helical repeat protein 10 domain DUF4200 PF13863.6 EGO53257.1 - 0.017 15.5 20.3 0.017 15.5 20.3 6.9 2 2 3 6 6 6 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.8 EGO53257.1 - 0.05 13.8 100.3 0.14 12.4 17.7 7.1 2 2 5 7 7 7 0 TATA element modulatory factor 1 TATA binding AIP3 PF03915.13 EGO53257.1 - 0.059 12.4 58.1 0.18 10.9 16.1 3.3 2 1 1 3 3 3 0 Actin interacting protein 3 Phage_GP20 PF06810.11 EGO53257.1 - 0.18 11.6 105.2 0.035 13.9 7.4 7.0 2 2 4 6 6 6 0 Phage minor structural protein GP20 Fez1 PF06818.15 EGO53257.1 - 0.21 12.0 99.5 0.17 12.3 20.8 5.5 1 1 4 5 5 5 0 Fez1 DUF4238 PF14022.6 EGO53257.1 - 0.35 10.3 0.0 0.35 10.3 0.0 3.5 2 2 1 3 3 1 0 Protein of unknown function (DUF4238) IFT57 PF10498.9 EGO53257.1 - 0.44 9.5 69.0 1 8.3 34.6 2.9 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 DUF812 PF05667.11 EGO53257.1 - 0.5 9.2 95.3 0.081 11.8 40.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.12 EGO53257.1 - 0.59 10.2 39.8 0.13 12.3 3.1 5.5 2 2 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cep57_CLD PF14073.6 EGO53257.1 - 0.67 10.0 0.0 0.67 10.0 0.0 5.6 3 2 2 5 5 3 0 Centrosome localisation domain of Cep57 DUF4250 PF14056.6 EGO53257.1 - 0.88 9.6 5.3 32 4.6 0.2 4.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) DUF4407 PF14362.6 EGO53257.1 - 1.5 8.1 100.8 0.31 10.3 18.5 5.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 EGO53257.1 - 2.1 8.4 117.1 0.056 13.5 21.5 6.4 2 2 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EGO53257.1 - 2.4 8.2 56.7 1.6 8.8 3.1 6.9 2 2 5 8 8 8 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 EGO53257.1 - 2.8 8.1 129.9 0.29 11.3 10.4 6.9 2 1 3 5 5 4 0 Autophagy protein 16 (ATG16) MAD PF05557.13 EGO53257.1 - 2.9 6.2 101.7 0.2 10.0 20.6 4.3 2 2 2 4 4 4 0 Mitotic checkpoint protein JIP_LZII PF16471.5 EGO53257.1 - 3.9 7.7 83.3 0.63 10.3 0.9 10.5 6 3 5 11 11 11 0 JNK-interacting protein leucine zipper II HMMR_N PF15905.5 EGO53257.1 - 4.3 6.7 99.5 3 7.3 29.3 5.1 2 2 2 4 4 4 0 Hyaluronan mediated motility receptor N-terminal NPV_P10 PF05531.12 EGO53257.1 - 4.9 7.7 42.2 11 6.6 2.5 6.8 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein zinc_ribbon_10 PF10058.9 EGO53258.1 - 3e-21 74.9 0.2 6.2e-21 73.9 0.2 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein zf-RanBP PF00641.18 EGO53258.1 - 0.9 8.9 3.3 1.1 8.6 0.5 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF3439 PF11921.8 EGO53259.1 - 0.013 15.4 1.6 0.013 15.4 1.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Xan_ur_permease PF00860.20 EGO53261.1 - 2.4e-23 82.5 33.9 2.2e-15 56.3 13.6 2.6 2 1 0 3 3 3 2 Permease family Imm61 PF15598.6 EGO53261.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 61 BAR PF03114.18 EGO53262.1 - 9e-18 64.8 0.1 1.3e-17 64.2 0.1 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EGO53262.1 - 5.2e-12 45.2 0.1 8.9e-12 44.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGO53262.1 - 1.1e-09 37.9 0.1 2.1e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGO53262.1 - 5.4e-09 35.8 0.0 9.3e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Caskin-Pro-rich PF16907.5 EGO53262.1 - 0.00049 20.6 1.8 0.00049 20.6 1.8 2.7 3 0 0 3 3 3 1 Proline rich region of Caskin proteins Pil1 PF13805.6 EGO53262.1 - 0.088 12.3 1.6 0.16 11.5 1.6 1.3 1 0 0 1 1 1 0 Eisosome component PIL1 DUF2439 PF10382.9 EGO53263.1 - 1.9e-26 92.2 0.2 4.1e-26 91.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Zn_clus PF00172.18 EGO53265.1 - 0.064 13.4 9.1 0.11 12.6 9.1 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain dCMP_cyt_deam_1 PF00383.23 EGO53266.1 - 3.9e-22 78.0 0.0 8.7e-22 76.9 0.0 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGO53266.1 - 2.5e-18 66.1 0.1 1.2e-07 31.6 0.0 3.1 3 0 0 3 3 3 2 MafB19-like deaminase Bd3614-deam PF14439.6 EGO53266.1 - 0.015 15.4 0.8 0.069 13.2 0.2 2.4 1 1 1 2 2 2 0 Bd3614-like deaminase Y_phosphatase3 PF13350.6 EGO53267.1 - 2e-51 175.2 0.0 2.9e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGO53267.1 - 7.8e-05 22.3 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EGO53267.1 - 0.0021 17.7 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family SR-25 PF10500.9 EGO53267.1 - 3.7 7.1 5.5 6.3 6.3 5.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MARVEL PF01284.23 EGO53268.1 - 0.00036 20.6 15.8 0.0016 18.5 14.1 2.0 1 1 1 2 2 2 2 Membrane-associating domain ABC2_membrane_5 PF13346.6 EGO53268.1 - 0.00047 19.8 2.7 0.00068 19.3 2.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein Oxidored_q3 PF00499.20 EGO53268.1 - 0.014 15.1 5.3 0.065 13.0 5.4 1.9 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 VIT1 PF01988.19 EGO53268.1 - 0.025 14.5 0.4 0.025 14.5 0.4 1.9 1 1 1 2 2 2 0 VIT family Tetraspanin PF00335.20 EGO53268.1 - 0.12 12.1 11.3 0.44 10.2 11.3 1.8 1 1 0 1 1 1 0 Tetraspanin family Bot1p PF12298.8 EGO53270.1 - 4.1e-52 176.8 1.5 6.8e-52 176.1 1.5 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein ANT PF03374.14 EGO53270.1 - 0.015 15.6 0.0 0.042 14.2 0.0 1.8 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain Response_reg PF00072.24 EGO53271.1 - 4.6e-20 71.9 0.0 8.1e-14 51.7 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain AAA_22 PF13401.6 EGO53272.1 - 0.0022 18.3 0.1 0.57 10.5 0.0 2.6 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 EGO53272.1 - 0.046 13.1 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EGO53272.1 - 0.078 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.17 EGO53272.1 - 0.091 12.8 0.0 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_16 PF13191.6 EGO53272.1 - 0.11 12.8 0.1 1.1 9.6 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain DUF1601 PF07671.11 EGO53272.1 - 5.2 7.0 5.0 6.5 6.7 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1601) DUF2052 PF09747.9 EGO53273.1 - 4.9e-26 92.1 0.4 1e-25 91.0 0.4 1.5 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) CC PF04942.14 EGO53275.1 - 0.073 13.3 0.8 0.073 13.3 0.8 1.9 2 0 0 2 2 2 0 CC domain LapA_dom PF06305.11 EGO53275.1 - 0.17 11.7 0.3 0.33 10.8 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Glyco_hydro_43 PF04616.14 EGO53276.1 - 2.4e-27 96.0 3.7 4.5e-25 88.5 3.7 2.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Lipase_3 PF01764.25 EGO53277.1 - 1.8e-15 57.0 0.0 2.4e-11 43.7 0.0 2.6 2 0 0 2 2 2 2 Lipase (class 3) Lpp-LpqN PF10738.9 EGO53277.1 - 0.086 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Probable lipoprotein LpqN Acetyltransf_1 PF00583.25 EGO53278.1 - 3.4e-11 43.4 0.0 4.3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO53278.1 - 1.9e-07 31.4 0.0 2.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGO53278.1 - 1.5e-06 28.2 0.0 2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1100 PF06500.11 EGO53280.1 - 6.7e-08 31.7 0.0 6.3e-06 25.2 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.21 EGO53280.1 - 0.00011 21.7 0.6 0.00027 20.5 0.6 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EGO53280.1 - 0.00061 19.5 1.0 0.00061 19.5 1.0 1.7 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EGO53280.1 - 0.0015 19.2 0.2 0.0015 19.2 0.2 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO53280.1 - 0.0044 16.3 0.1 0.0072 15.6 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 EGO53280.1 - 0.0077 15.8 0.1 0.021 14.3 0.2 1.6 2 0 0 2 2 2 1 Esterase PHB depolymerase Ndr PF03096.14 EGO53280.1 - 0.05 12.3 0.0 0.18 10.4 0.1 1.7 1 1 0 2 2 2 0 Ndr family Abhydrolase_3 PF07859.13 EGO53280.1 - 0.09 12.6 0.0 0.99 9.2 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold RRS1 PF04939.12 EGO53280.1 - 0.63 9.9 4.2 0.46 10.3 1.6 1.8 1 1 0 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) adh_short_C2 PF13561.6 EGO53281.1 - 2.4e-56 190.9 0.0 2.9e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO53281.1 - 5e-51 173.0 0.2 9.5e-51 172.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EGO53281.1 - 2.3e-13 50.5 0.3 6.6e-13 49.0 0.3 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO53281.1 - 1.7e-06 27.7 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EGO53281.1 - 0.031 13.8 0.8 0.22 11.1 0.3 2.5 2 1 0 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.6 EGO53281.1 - 0.036 14.0 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 EGO53281.1 - 0.097 12.0 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EGO53281.1 - 0.099 12.0 0.1 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGO53281.1 - 0.12 11.5 0.1 0.38 9.8 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain ADH_N PF08240.12 EGO53282.1 - 3.1e-19 68.9 2.7 3.5e-18 65.5 0.5 2.7 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO53282.1 - 1.3e-14 54.3 0.2 2.4e-14 53.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGO53282.1 - 5.2e-06 26.1 0.1 0.069 12.6 0.1 2.4 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EGO53282.1 - 0.0022 17.3 0.4 0.0048 16.2 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Aldo_ket_red PF00248.21 EGO53283.1 - 2.5e-48 164.8 0.0 1.8e-46 158.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.13 EGO53283.1 - 0.14 11.7 0.0 0.62 9.6 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family SNARE PF05739.19 EGO53284.1 - 9e-15 54.4 0.1 2e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 EGO53284.1 - 0.00019 20.5 0.4 0.00045 19.4 0.4 1.7 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 EGO53284.1 - 0.0002 21.1 0.3 0.0002 21.1 0.3 3.0 2 1 1 3 3 3 1 Syntaxin Snapin_Pallidin PF14712.6 EGO53284.1 - 0.0027 18.1 2.3 1.6 9.2 0.1 2.6 2 0 0 2 2 2 2 Snapin/Pallidin Prominin PF05478.11 EGO53284.1 - 0.0044 15.1 1.2 0.19 9.6 0.1 2.2 2 0 0 2 2 2 2 Prominin TRPM_tetra PF16519.5 EGO53284.1 - 0.0053 16.8 2.7 0.012 15.7 0.2 2.9 3 0 0 3 3 3 1 Tetramerisation domain of TRPM KxDL PF10241.9 EGO53284.1 - 0.0072 16.6 6.6 0.95 9.8 0.8 3.5 2 2 0 3 3 3 2 Uncharacterized conserved protein Peripla_BP_2 PF01497.18 EGO53284.1 - 0.013 15.1 0.5 0.025 14.1 0.5 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Syntaxin-18_N PF10496.9 EGO53284.1 - 0.014 15.6 0.3 0.057 13.7 0.1 2.1 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus NPV_P10 PF05531.12 EGO53284.1 - 0.026 15.0 2.8 17 6.0 0.2 3.6 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.21 EGO53284.1 - 0.043 13.6 4.5 0.051 13.4 1.1 2.4 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 EGO53284.1 - 0.058 13.4 2.2 1.5 8.8 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SOAR PF16533.5 EGO53284.1 - 0.066 13.2 0.6 0.22 11.5 0.6 1.8 1 0 0 1 1 1 0 STIM1 Orai1-activating region DUF16 PF01519.16 EGO53284.1 - 0.072 13.6 4.2 0.11 13.0 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4988 PF16378.5 EGO53284.1 - 0.23 11.1 4.5 4.6 6.9 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function Spectrin PF00435.21 EGO53284.1 - 2.8 8.5 7.6 4.2 7.9 0.2 3.7 2 2 2 4 4 4 0 Spectrin repeat Sec2p PF06428.11 EGO53287.1 - 1.4e-27 95.5 26.6 3.3e-27 94.3 18.6 2.7 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p DUF5401 PF17380.2 EGO53287.1 - 0.68 7.9 18.9 1.4 6.9 18.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Med9 PF07544.13 EGO53287.1 - 2 8.5 18.5 0.38 10.9 0.5 3.4 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Zip PF02535.22 EGO53288.1 - 2.7e-27 95.9 29.8 9e-14 51.4 3.2 4.9 2 1 3 5 5 5 3 ZIP Zinc transporter Sporozoite_P67 PF05642.11 EGO53289.1 - 0.35 8.9 5.6 0.41 8.7 5.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.25 EGO53292.1 - 1.3e-36 126.3 0.0 1.9e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO53292.1 - 2.3e-15 56.6 0.0 5.3e-15 55.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO53292.1 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGO53292.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family RVT_1 PF00078.27 EGO53296.1 - 0.045 13.3 0.2 0.045 13.3 0.2 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Aldo_ket_red PF00248.21 EGO53297.1 - 2.5e-66 223.9 0.0 3.1e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GST_N_3 PF13417.6 EGO53298.1 - 1.1e-07 32.2 0.1 2.2e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO53298.1 - 1.3e-07 31.5 0.0 2.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGO53298.1 - 1.4e-06 28.5 0.1 2.3e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO53298.1 - 0.00013 22.1 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO53298.1 - 0.0099 16.1 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF5545 PF17699.1 EGO53301.1 - 0.005 16.7 3.6 0.0076 16.1 3.6 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5545) FMO-like PF00743.19 EGO53304.1 - 2e-14 53.0 0.0 5.6e-14 51.5 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EGO53304.1 - 2e-11 44.0 0.0 5.6e-08 32.9 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGO53304.1 - 5.1e-10 39.1 0.0 5.6e-08 32.4 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO53304.1 - 8.8e-09 35.0 0.0 9e-07 28.4 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO53304.1 - 1.3e-06 28.3 0.0 0.39 10.2 0.0 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 EGO53304.1 - 3.7e-06 26.3 0.0 8.8e-05 21.9 0.0 2.4 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 EGO53304.1 - 8e-06 25.2 0.5 0.00023 20.5 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EGO53304.1 - 0.0002 21.8 0.0 0.05 14.2 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGO53304.1 - 0.00063 19.2 0.0 0.012 14.9 0.0 2.6 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 EGO53304.1 - 0.02 14.9 0.0 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EGO53304.1 - 0.069 13.6 0.0 0.15 12.6 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 EGO53304.1 - 0.076 12.1 0.1 8.9 5.3 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EGO53304.1 - 0.086 12.2 0.0 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGO53304.1 - 0.15 12.0 0.2 83 3.1 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding NUDIX PF00293.28 EGO53306.1 - 3.5e-19 69.2 0.4 4e-19 69.0 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain Fungal_trans PF04082.18 EGO53307.1 - 7.8e-20 71.0 0.1 1.2e-19 70.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO53307.1 - 3.9e-09 36.5 11.0 6.5e-09 35.8 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.7 EGO53308.1 - 0.00013 22.5 0.0 0.00085 19.9 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) AAA_16 PF13191.6 EGO53308.1 - 0.00043 20.7 0.0 0.0013 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EGO53308.1 - 0.0016 18.4 0.3 0.0054 16.7 0.3 1.9 1 1 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 EGO53308.1 - 0.0042 17.0 0.0 0.0086 16.0 0.0 1.5 1 0 0 1 1 1 1 NTPase Ank_3 PF13606.6 EGO53308.1 - 0.0084 16.5 0.2 0.21 12.3 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat AAA_22 PF13401.6 EGO53308.1 - 0.023 15.0 0.0 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EGO53308.1 - 0.16 11.1 0.2 1.1 8.4 0.1 2.0 1 1 0 2 2 2 0 KAP family P-loop domain Ank PF00023.30 EGO53308.1 - 1.3 9.6 3.4 53 4.5 2.8 3.5 2 1 0 2 2 2 0 Ankyrin repeat DUF5427 PF10310.9 EGO53310.1 - 6.5e-181 602.3 0.0 7.5e-181 602.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) SARAF PF06682.12 EGO53310.1 - 0.11 12.1 4.2 0.2 11.3 4.2 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Flu_M1_C PF08289.11 EGO53310.1 - 0.15 12.3 0.4 0.39 11.0 0.4 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Ndc1_Nup PF09531.10 EGO53310.1 - 0.68 8.5 2.1 0.99 8.0 2.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2076 PF09849.9 EGO53310.1 - 3.8 7.5 11.7 0.83 9.6 7.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) CDC27 PF09507.10 EGO53310.1 - 5.9 6.2 18.2 0.97 8.7 13.5 1.9 2 1 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF5404 PF17397.2 EGO53315.1 - 0.045 13.9 3.9 0.075 13.2 3.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5404) DUF202 PF02656.15 EGO53315.1 - 3.7 8.1 9.4 4.7 7.7 1.4 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Abhydrolase_1 PF00561.20 EGO53316.1 - 1.9e-19 70.3 0.0 1.1e-18 67.9 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO53316.1 - 2.3e-16 61.1 0.0 3.4e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO53316.1 - 5.3e-11 42.2 0.0 1.4e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 EGO53316.1 - 2.2e-05 24.2 0.3 0.0021 17.8 0.1 2.7 2 1 0 2 2 2 1 Putative esterase Abhydrolase_5 PF12695.7 EGO53316.1 - 0.0067 16.2 0.0 0.04 13.7 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EGO53316.1 - 0.028 14.2 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.13 EGO53316.1 - 0.03 14.2 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase Thioesterase PF00975.20 EGO53316.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Ndr PF03096.14 EGO53316.1 - 0.065 11.9 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family Acyl_transf_1 PF00698.21 EGO53316.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase domain Ribosomal_L14 PF00238.19 EGO53317.1 - 9.1e-33 112.9 0.0 1.1e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Malic_M PF03949.15 EGO53318.1 - 1e-90 303.5 0.0 1.3e-90 303.2 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EGO53318.1 - 6.7e-57 192.2 0.0 1.3e-56 191.3 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Inhibitor_I53 PF11714.8 EGO53319.1 - 0.12 12.5 0.2 0.16 12.1 0.2 1.1 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Glyco_hydro_75 PF07335.11 EGO53321.1 - 2e-60 203.8 0.8 2.5e-60 203.4 0.8 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 CFEM PF05730.11 EGO53322.1 - 1.3e-06 28.4 3.4 2.9e-06 27.3 3.4 1.7 1 0 0 1 1 1 1 CFEM domain AF-4 PF05110.13 EGO53322.1 - 4.7 5.2 7.1 5.1 5.1 7.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MNR PF15718.5 EGO53324.1 - 0.013 13.7 0.3 0.019 13.1 0.3 1.2 1 0 0 1 1 1 0 Protein moonraker Cwf_Cwc_15 PF04889.12 EGO53324.1 - 0.024 14.4 5.5 0.025 14.3 5.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 EGO53324.1 - 0.23 11.7 7.2 0.28 11.4 7.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Astro_capsid_p PF12226.8 EGO53324.1 - 4.3 6.4 7.1 5.1 6.2 7.1 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein NACHT PF05729.12 EGO53325.1 - 3.5e-10 40.0 0.2 8.6e-10 38.8 0.2 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGO53325.1 - 2.2e-06 28.1 1.9 6e-06 26.7 0.1 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EGO53325.1 - 1.1e-05 25.5 0.0 3.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EGO53325.1 - 2.4e-05 24.7 0.1 0.37 11.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EGO53325.1 - 3.1e-05 24.4 0.3 0.00037 20.9 0.0 3.0 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO53325.1 - 0.00013 22.3 0.4 0.00044 20.5 0.1 2.1 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 EGO53325.1 - 0.00024 20.4 0.0 0.00047 19.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain PPV_E1_C PF00519.17 EGO53325.1 - 0.0012 17.8 0.0 0.0021 17.0 0.0 1.5 1 0 0 1 1 1 1 Papillomavirus helicase Torsin PF06309.11 EGO53325.1 - 0.014 15.5 0.1 0.11 12.6 0.0 2.5 3 0 0 3 3 2 0 Torsin DUF2075 PF09848.9 EGO53325.1 - 0.023 13.9 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 EGO53325.1 - 0.024 14.8 0.2 0.2 11.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain KTI12 PF08433.10 EGO53325.1 - 0.035 13.6 0.1 0.2 11.0 0.0 2.3 2 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 EGO53325.1 - 0.038 14.5 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGO53325.1 - 0.045 13.3 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EGO53325.1 - 0.049 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 EGO53325.1 - 0.067 12.4 4.5 7.2 5.8 0.0 3.7 2 1 2 4 4 4 0 KAP family P-loop domain APS_kinase PF01583.20 EGO53325.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase MA3 PF02847.17 EGO53325.1 - 0.57 10.2 2.3 28 4.7 0.1 2.9 3 0 0 3 3 2 0 MA3 domain SNF2_N PF00176.23 EGO53326.1 - 2.4e-49 168.0 0.0 6.9e-48 163.1 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EGO53326.1 - 1.7e-05 24.9 0.0 0.0037 17.3 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EGO53326.1 - 0.00027 20.7 0.0 0.049 13.3 0.0 2.3 2 0 0 2 2 2 2 SWI2/SNF2 ATPase Helicase_C PF00271.31 EGO53327.1 - 1.6e-05 25.2 0.1 1.8e-05 25.1 0.1 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IBR PF01485.21 EGO53328.1 - 1e-09 38.5 16.2 1.9e-06 28.0 2.8 3.8 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EGO53328.1 - 0.0012 18.6 10.3 0.0012 18.6 10.3 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO53328.1 - 0.0029 17.4 11.7 0.0029 17.4 11.7 3.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO53328.1 - 0.0029 17.4 10.2 0.0029 17.4 10.2 4.5 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) RhoGAP PF00620.27 EGO53329.1 - 2.2e-19 69.8 0.0 4.2e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Helo_like_N PF17111.5 EGO53329.1 - 5.3e-08 32.5 0.0 9.3e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins CRIC_ras_sig PF10534.9 EGO53329.1 - 0.13 12.4 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras DEC-1_N PF04625.13 EGO53329.1 - 4.1 6.3 8.2 7.6 5.4 8.2 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Glyco_hydro_61 PF03443.14 EGO53330.1 - 1.8e-59 201.1 0.1 2.7e-59 200.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EGO53330.1 - 2.3e-13 49.8 16.9 6.1e-13 48.5 11.2 2.8 2 0 0 2 2 2 2 Fungal cellulose binding domain DUF3157 PF11355.8 EGO53331.1 - 0.0062 16.2 0.0 0.0083 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3157) Methyltransf_31 PF13847.6 EGO53331.1 - 0.0078 16.0 0.0 0.0097 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain ketoacyl-synt PF00109.26 EGO53332.1 - 1.3e-68 231.4 0.1 4e-68 229.7 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EGO53332.1 - 2.9e-54 184.3 0.0 4.7e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EGO53332.1 - 1.4e-50 171.7 0.5 4.5e-50 170.0 0.0 2.2 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 EGO53332.1 - 4.8e-49 167.6 0.1 8e-49 166.9 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGO53332.1 - 3.3e-39 133.6 0.3 1.4e-38 131.6 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGO53332.1 - 5.1e-18 65.6 0.0 2.1e-17 63.6 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGO53332.1 - 5.6e-10 40.4 3.5 2.8e-09 38.1 0.3 3.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase adh_short PF00106.25 EGO53332.1 - 2.8e-05 23.7 0.0 0.00013 21.5 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 EGO53332.1 - 4.2e-05 23.5 2.7 0.0004 20.4 0.5 3.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO53332.1 - 4.3e-05 23.4 0.0 0.00016 21.5 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGO53332.1 - 7.9e-05 22.9 0.1 0.00022 21.5 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EGO53332.1 - 0.0071 15.7 0.2 0.022 14.1 0.2 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain DHQS PF01959.16 EGO53332.1 - 0.16 10.9 1.7 3.5 6.4 0.8 2.3 2 0 0 2 2 2 0 3-dehydroquinate synthase II ACP_syn_III PF08545.10 EGO53332.1 - 1 9.3 3.2 0.65 9.9 0.6 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cupin_2 PF07883.11 EGO53333.1 - 6.9e-09 35.3 0.0 1.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Auxin_BP PF02041.16 EGO53333.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein adh_short_C2 PF13561.6 EGO53334.1 - 4.4e-55 186.8 7.4 1.1e-54 185.5 7.4 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO53334.1 - 2.4e-42 144.6 5.1 4.2e-42 143.8 5.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO53334.1 - 1.4e-06 28.3 1.0 3.9e-05 23.6 0.5 2.3 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 EGO53334.1 - 0.011 15.8 0.1 0.028 14.5 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Trp_syntA PF00290.20 EGO53334.1 - 0.026 13.4 0.1 0.04 12.8 0.1 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain ThiF PF00899.21 EGO53334.1 - 0.034 13.5 1.0 0.034 13.5 1.0 1.7 2 0 0 2 2 2 0 ThiF family Cupin_2 PF07883.11 EGO53335.1 - 1.9e-05 24.3 0.0 4.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Cupin domain adh_short PF00106.25 EGO53336.1 - 1e-35 123.0 0.0 1.4e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO53336.1 - 6.1e-27 94.7 0.0 7.9e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO53336.1 - 0.006 16.5 0.6 0.017 15.0 0.6 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO53336.1 - 0.038 13.5 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EGO53337.1 - 8.8e-20 71.0 0.0 1.2e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO53337.1 - 4.1e-15 56.0 0.0 5.1e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Abhydrolase_1 PF00561.20 EGO53338.1 - 1.1e-18 67.9 0.0 1.6e-14 54.2 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO53338.1 - 5.6e-15 56.5 0.2 8.3e-15 56.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO53338.1 - 2e-06 27.3 0.0 2.9e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 EHN PF06441.12 EGO53338.1 - 0.0079 16.5 0.6 0.023 15.0 0.1 2.0 2 0 0 2 2 2 1 Epoxide hydrolase N terminus FAD_binding_3 PF01494.19 EGO53339.1 - 1.9e-22 80.0 0.0 1.3e-14 54.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EGO53339.1 - 1.9e-11 43.8 0.0 2e-07 30.6 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGO53339.1 - 8.3e-08 31.7 0.0 1.7e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EGO53339.1 - 6.8e-07 28.8 0.0 0.015 14.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO53339.1 - 4.3e-05 24.0 0.0 0.008 16.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO53339.1 - 0.0001 21.2 0.0 0.021 13.5 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 EGO53339.1 - 0.00039 20.6 0.0 0.0013 18.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGO53339.1 - 0.0076 16.2 0.2 0.91 9.5 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EGO53339.1 - 0.022 14.3 0.6 0.37 10.3 0.1 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EGO53339.1 - 0.085 12.1 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase TrkA_N PF02254.18 EGO53339.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_4 PF01565.23 EGO53340.1 - 2.2e-27 95.5 1.5 3.8e-27 94.7 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGO53340.1 - 2.6e-11 43.4 0.1 5.7e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 EGO53341.1 - 3.2e-22 78.8 0.1 5.2e-22 78.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGO53341.1 - 4.3e-07 29.9 0.1 1e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Aldo_ket_red PF00248.21 EGO53344.1 - 1.3e-58 198.5 0.0 1.5e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.8 EGO53345.1 - 0.0045 15.9 1.3 0.038 12.8 1.4 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyc_hyd_38C_2 PF18230.1 EGO53345.1 - 0.17 12.0 0.2 0.39 10.9 0.2 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal sub-domain Endosulfine PF04667.17 EGO53346.1 - 6.3e-16 58.3 0.0 2.5e-11 43.6 0.0 2.3 2 0 0 2 2 2 2 cAMP-regulated phosphoprotein/endosulfine conserved region Fungal_trans PF04082.18 EGO53347.1 - 2.5e-13 49.7 0.0 4e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO53347.1 - 9.3e-08 32.1 8.2 1.9e-07 31.1 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CGI-121 PF08617.10 EGO53348.1 - 4.4e-50 170.0 0.0 5.3e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Lipoprotein_18 PF06804.11 EGO53348.1 - 0.027 13.5 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 NlpB/DapX lipoprotein Pro_dh PF01619.18 EGO53349.1 - 7.9e-66 222.6 0.0 1e-65 222.2 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase SHS2_Rpb7-N PF03876.17 EGO53349.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Tim17 PF02466.19 EGO53350.1 - 0.03 14.7 6.5 0.03 14.7 4.5 1.9 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 EGO53350.1 - 4.2 7.8 8.6 2.1 8.7 0.6 3.1 3 1 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 RraA-like PF03737.15 EGO53354.1 - 6.4e-34 117.3 0.0 9.1e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Aldolase/RraA NIF PF03031.18 EGO53356.1 - 1.3e-39 135.5 0.0 1.9e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Mt_ATP-synt_B PF05405.14 EGO53356.1 - 0.21 11.2 0.1 0.21 11.2 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) LETM1 PF07766.13 EGO53356.1 - 0.26 10.6 1.7 0.4 10.0 0.4 1.9 2 0 0 2 2 2 0 LETM1-like protein SUIM_assoc PF16619.5 EGO53356.1 - 0.63 10.2 13.8 0.96 9.6 8.4 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CR6_interact PF10147.9 EGO53358.1 - 0.1 12.3 8.4 0.23 11.2 8.4 1.5 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Mito_carr PF00153.27 EGO53359.1 - 4.7e-18 64.9 3.9 5.5e-06 26.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Amidase PF01425.21 EGO53360.1 - 0.0013 17.7 0.0 0.004 16.2 0.0 1.7 1 1 1 2 2 2 1 Amidase DUF2735 PF10931.8 EGO53360.1 - 0.17 12.6 0.0 0.37 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) FMN_red PF03358.15 EGO53361.1 - 8.8e-08 32.0 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EGO53361.1 - 3.7e-05 23.5 0.0 4.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 EGO53361.1 - 6.5e-05 23.2 0.7 0.00046 20.4 0.7 2.2 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EGO53361.1 - 0.065 13.5 0.0 4.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain Yae1_N PF09811.9 EGO53362.1 - 3.7e-13 48.9 1.6 7.5e-13 47.9 1.6 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal TFIIA PF03153.13 EGO53362.1 - 0.00049 20.2 21.2 0.00049 20.2 21.2 1.7 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 EGO53362.1 - 0.0031 16.3 11.5 0.0031 16.3 11.5 1.6 2 0 0 2 2 2 1 Presenilin NPR3 PF03666.13 EGO53362.1 - 0.0032 16.3 12.5 0.0052 15.6 12.5 1.4 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 EGO53362.1 - 0.013 14.5 7.9 0.017 14.2 7.9 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Pex14_N PF04695.13 EGO53362.1 - 0.026 15.2 16.6 0.076 13.7 16.6 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peroxin-13_N PF04088.13 EGO53362.1 - 0.033 14.5 1.5 0.076 13.3 1.5 1.6 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Spt20 PF12090.8 EGO53362.1 - 0.042 13.5 39.4 0.071 12.7 39.4 1.3 1 0 0 1 1 1 0 Spt20 family SpoIIP PF07454.11 EGO53362.1 - 0.082 12.4 17.0 0.19 11.2 17.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) MAT1 PF06391.13 EGO53362.1 - 0.084 12.7 21.2 0.16 11.8 21.2 1.4 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Ndc1_Nup PF09531.10 EGO53362.1 - 0.14 10.8 5.6 0.16 10.6 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Membralin PF09746.9 EGO53362.1 - 0.15 11.1 5.8 0.2 10.7 5.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein Romo1 PF10247.9 EGO53362.1 - 0.24 11.8 1.4 0.4 11.1 1.4 1.3 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 SID-1_RNA_chan PF13965.6 EGO53362.1 - 0.28 9.5 3.4 0.32 9.3 3.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MDM10 PF12519.8 EGO53362.1 - 0.36 9.7 10.9 0.53 9.1 10.9 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Tim54 PF11711.8 EGO53362.1 - 0.36 9.6 16.5 0.76 8.5 16.5 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Tfb4 PF03850.14 EGO53362.1 - 0.36 10.3 3.1 0.52 9.8 3.1 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 PAT1 PF09770.9 EGO53362.1 - 0.37 9.0 23.3 0.017 13.5 17.8 1.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Suf PF05843.14 EGO53362.1 - 0.41 10.6 13.4 0.74 9.7 13.4 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 EGO53362.1 - 0.47 9.4 19.9 0.67 8.9 19.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.7 EGO53362.1 - 0.68 8.0 12.3 0.88 7.6 12.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF913 PF06025.12 EGO53362.1 - 0.79 8.6 8.4 1.3 7.9 8.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CCDC53 PF10152.9 EGO53362.1 - 0.81 10.1 16.6 0.73 10.2 14.7 1.9 2 0 0 2 2 1 0 Subunit CCDC53 of WASH complex DUF2151 PF10221.9 EGO53362.1 - 1.1 7.8 9.2 1.5 7.3 9.2 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator FAM91_C PF14648.6 EGO53362.1 - 1.2 7.9 4.9 1.7 7.4 4.9 1.2 1 0 0 1 1 1 0 FAM91 C-terminus ALMT PF11744.8 EGO53362.1 - 1.3 7.8 8.4 1.8 7.3 8.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Otopetrin PF03189.13 EGO53362.1 - 1.3 7.7 4.3 2.1 7.1 4.3 1.3 1 0 0 1 1 1 0 Otopetrin Neur_chan_memb PF02932.16 EGO53362.1 - 2.2 8.3 10.8 0.68 10.0 7.8 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Cellulose_synt PF03552.14 EGO53362.1 - 2.2 6.6 3.4 2.8 6.3 3.4 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF702 PF05142.12 EGO53362.1 - 3.4 8.1 12.8 7.9 7.0 12.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Connexin PF00029.19 EGO53362.1 - 3.5 7.3 11.6 10 5.8 11.6 1.8 1 0 0 1 1 1 0 Connexin Borrelia_P83 PF05262.11 EGO53362.1 - 3.7 5.9 15.5 4.3 5.7 15.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein GREB1 PF15782.5 EGO53362.1 - 3.7 4.5 11.3 4.5 4.2 11.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PepSY_TM PF03929.16 EGO53362.1 - 5.4 6.6 9.4 1.8 8.2 6.7 1.6 2 0 0 2 2 2 0 PepSY-associated TM region PIP5K PF01504.18 EGO53362.1 - 5.4 6.1 12.2 11 5.2 12.2 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF4175 PF13779.6 EGO53362.1 - 5.8 4.7 32.5 8 4.2 32.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4746 PF15928.5 EGO53362.1 - 6.5 6.1 22.6 0.91 8.9 17.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DUF4407 PF14362.6 EGO53362.1 - 7.5 5.8 15.9 11 5.2 15.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CLN3 PF02487.17 EGO53362.1 - 8.8 5.3 11.1 14 4.6 11.1 1.2 1 0 0 1 1 1 0 CLN3 protein GLTT PF01744.20 EGO53363.1 - 0.26 11.1 4.1 0.4 10.5 0.5 2.8 3 0 0 3 3 3 0 GLTT repeat (6 copies) Ribosomal_S8 PF00410.19 EGO53364.1 - 8.2e-16 58.1 0.0 3.2e-15 56.2 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S8 Iso_dh PF00180.20 EGO53365.1 - 3.8e-100 335.4 0.0 5e-100 335.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GTP_EFTU PF00009.27 EGO53366.1 - 5.1e-60 202.3 0.4 9.6e-60 201.4 0.4 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGO53366.1 - 3.7e-35 120.3 0.0 8.8e-35 119.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EGO53366.1 - 3.2e-33 113.6 0.0 6.5e-33 112.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EGO53366.1 - 1.2e-21 76.5 0.0 2.7e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGO53366.1 - 1.7e-12 47.5 0.0 4e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EGO53366.1 - 2.6e-07 30.5 0.0 6.2e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EGO53366.1 - 0.02 15.0 0.1 0.046 13.8 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF442 PF04273.13 EGO53366.1 - 0.049 13.7 0.0 1.8 8.7 0.0 3.0 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Asp PF00026.23 EGO53367.1 - 7.7e-65 219.4 1.2 1.2e-64 218.8 1.2 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO53367.1 - 2.2e-11 44.3 2.5 9.5e-07 29.2 0.2 2.7 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO53367.1 - 0.0024 18.5 0.3 0.29 11.8 0.2 3.1 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 EGO53367.1 - 0.016 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGO53367.1 - 0.032 14.8 0.0 2.8 8.5 0.0 3.0 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease DUF4044 PF13253.6 EGO53367.1 - 1.2 8.7 6.2 2.4 7.7 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) HLH PF00010.26 EGO53368.1 - 1.9e-12 47.0 0.8 5.9e-12 45.4 0.8 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4776 PF16003.5 EGO53368.1 - 0.011 14.7 2.1 0.017 14.1 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Josephin PF02099.17 EGO53368.1 - 0.021 14.9 1.3 0.048 13.8 1.3 1.5 1 0 0 1 1 1 0 Josephin DUF641 PF04859.12 EGO53368.1 - 0.029 14.7 5.0 0.067 13.5 5.0 1.7 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Csm1_N PF18504.1 EGO53368.1 - 0.22 11.9 3.4 0.21 11.9 0.3 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain UPF0242 PF06785.11 EGO53368.1 - 0.26 11.3 5.4 0.37 10.9 3.5 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Phage_GPO PF05929.11 EGO53368.1 - 0.39 10.3 3.0 0.27 10.8 1.3 1.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RRM_1 PF00076.22 EGO53371.1 - 2e-33 114.0 0.1 1.1e-15 57.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EGO53371.1 - 0.024 14.4 0.0 1.7 8.4 0.0 2.7 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 EGO53371.1 - 0.16 12.1 0.1 20 5.4 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif TPR_2 PF07719.17 EGO53372.1 - 1.9e-24 83.7 4.9 9.7e-07 28.4 0.2 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGO53372.1 - 1e-23 82.1 6.1 1e-07 31.5 0.1 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGO53372.1 - 5.7e-18 65.3 6.8 9.8e-07 29.3 0.2 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGO53372.1 - 2e-17 62.6 2.6 1.2e-07 31.3 0.1 5.0 3 2 2 5 5 5 3 TPR repeat TPR_14 PF13428.6 EGO53372.1 - 5.9e-17 60.9 5.7 6.2e-06 26.6 0.1 6.0 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGO53372.1 - 7.3e-16 57.3 2.9 0.0036 17.6 0.1 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGO53372.1 - 2.8e-14 53.4 4.9 2.4e-05 24.8 1.5 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO53372.1 - 4.2e-14 51.5 0.7 9.1e-05 22.4 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGO53372.1 - 2.1e-13 49.2 2.1 0.0063 16.5 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGO53372.1 - 7.8e-12 45.3 6.5 4e-05 23.8 1.4 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGO53372.1 - 8.2e-12 45.1 0.4 0.00089 19.4 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGO53372.1 - 6.2e-10 39.3 1.4 0.01 16.2 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGO53372.1 - 6.2e-10 39.1 4.1 1.4 9.7 0.0 6.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 EGO53372.1 - 1.1e-05 24.8 0.9 0.053 12.7 0.3 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO53372.1 - 6.9e-05 23.0 3.1 0.36 11.1 0.1 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGO53372.1 - 0.015 15.1 0.6 0.015 15.1 0.6 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGO53372.1 - 0.035 14.1 0.1 6.2 6.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4919 PF16266.5 EGO53372.1 - 0.048 13.6 0.1 0.14 12.1 0.0 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4919) CRISPR_Cse2 PF09485.10 EGO53372.1 - 0.11 13.0 2.1 0.25 11.8 0.2 2.3 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF1641 PF07849.11 EGO53372.1 - 0.12 12.2 0.2 0.29 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) MIT PF04212.18 EGO53372.1 - 0.32 11.1 2.3 25 5.0 0.0 3.4 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 EGO53372.1 - 0.88 10.0 4.6 31 5.0 0.2 3.3 2 1 1 3 3 3 0 Bacterial transcriptional activator domain RNase_T PF00929.24 EGO53373.1 - 1.1e-07 32.6 0.0 8.5e-07 29.7 0.0 2.4 2 1 0 2 2 2 1 Exonuclease SET PF00856.28 EGO53374.1 - 9.9e-14 52.1 0.0 1.3e-12 48.4 0.0 2.6 2 2 0 2 2 2 1 SET domain zf-MYND PF01753.18 EGO53374.1 - 4.6e-08 33.0 11.0 4.6e-08 33.0 11.0 2.1 2 0 0 2 2 2 1 MYND finger Prefoldin PF02996.17 EGO53375.1 - 2.2e-26 92.1 0.3 3.1e-26 91.6 0.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EGO53375.1 - 0.0011 18.9 2.4 0.42 10.6 0.4 2.1 2 0 0 2 2 2 2 Prefoldin subunit DUF1664 PF07889.12 EGO53375.1 - 0.016 15.3 1.2 0.23 11.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GIT_CC PF16559.5 EGO53375.1 - 0.021 14.7 0.9 0.82 9.6 0.4 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor UvsW PF11637.8 EGO53375.1 - 0.028 14.5 0.1 0.095 12.8 0.0 1.9 2 0 0 2 2 2 0 ATP-dependant DNA helicase UvsW Tektin PF03148.14 EGO53375.1 - 0.086 11.6 1.2 1.8 7.2 0.2 2.0 2 0 0 2 2 2 0 Tektin family DUF1192 PF06698.11 EGO53375.1 - 0.09 12.8 0.3 0.74 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) IFP_35_N PF07334.13 EGO53375.1 - 0.26 11.4 1.9 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Pro_Al_protease PF02983.14 EGO53375.1 - 1.2 9.3 3.9 8.4 6.5 1.5 2.9 2 1 0 2 2 2 0 Alpha-lytic protease prodomain KH_1 PF00013.29 EGO53376.1 - 0.082 12.8 0.5 0.2 11.5 0.5 1.7 1 0 0 1 1 1 0 KH domain AAA PF00004.29 EGO53380.1 - 1.6e-15 57.7 0.0 2.8e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 EGO53380.1 - 1.4e-10 41.2 0.6 3.5e-10 39.9 0.6 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 EGO53380.1 - 2.7e-10 40.9 0.2 3.5e-09 37.3 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EGO53380.1 - 7.8e-09 35.9 0.0 2.4e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain BAH PF01426.18 EGO53380.1 - 0.00063 19.6 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 EGO53380.1 - 0.001 19.4 0.0 0.0023 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO53380.1 - 0.018 15.2 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGO53380.1 - 0.033 14.7 0.0 0.079 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGO53380.1 - 0.051 13.4 0.1 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGO53380.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGO53380.1 - 0.066 12.9 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain ssDBP PF17878.1 EGO53380.1 - 0.081 13.2 0.0 0.27 11.5 0.0 1.8 2 0 0 2 2 1 0 Single-stranded DNA-binding protein AAA_32 PF13654.6 EGO53380.1 - 0.084 11.6 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGO53380.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 EGO53380.1 - 0.19 10.9 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PBP1_TM PF14812.6 EGO53380.1 - 8.9 6.8 8.8 6.2 7.3 1.2 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.32 EGO53381.1 - 3.5e-44 147.9 16.7 4.6e-10 39.9 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO53381.1 - 2.5e-05 24.5 0.2 1.1 9.6 0.0 4.6 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO53381.1 - 0.0037 16.0 1.0 3.7 6.1 0.1 3.3 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Ank_2 PF12796.7 EGO53382.1 - 4.1e-35 120.2 0.9 3.5e-12 46.7 0.2 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO53382.1 - 1.4e-33 114.8 5.7 1.2e-09 38.5 0.2 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO53382.1 - 6.5e-32 109.2 2.8 1.2e-08 35.0 0.0 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO53382.1 - 1.3e-30 102.0 0.4 1.7e-05 24.8 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 EGO53382.1 - 7e-28 95.8 2.5 0.00034 20.9 0.1 6.2 6 0 0 6 6 6 5 Ankyrin repeat TMF_TATA_bd PF12325.8 EGO53383.1 - 2.4e-40 137.3 13.6 2.4e-40 137.3 13.6 6.8 3 2 3 6 6 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EGO53383.1 - 3e-18 65.6 20.0 3e-18 65.6 20.0 9.2 4 3 5 9 9 9 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 EGO53383.1 - 0.00064 20.0 12.2 0.00064 20.0 12.2 7.1 2 2 3 5 5 5 1 Autophagy protein 16 (ATG16) Filament PF00038.21 EGO53383.1 - 0.025 14.2 92.9 0.081 12.5 9.1 3.5 2 1 1 3 3 3 0 Intermediate filament protein Baculo_PEP_C PF04513.12 EGO53383.1 - 0.33 11.0 15.7 0.97 9.5 2.1 4.2 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ceramidase PF05875.12 EGO53384.1 - 7.7e-98 327.1 13.7 9e-98 326.9 13.7 1.0 1 0 0 1 1 1 1 Ceramidase DUF2157 PF09925.9 EGO53384.1 - 0.0028 17.5 9.0 0.0034 17.2 3.0 2.2 1 1 1 2 2 2 2 Predicted membrane protein (DUF2157) EamA PF00892.20 EGO53384.1 - 0.0064 16.7 7.6 0.0092 16.2 2.4 2.4 2 0 0 2 2 2 1 EamA-like transporter family DUF2070 PF09843.9 EGO53384.1 - 7.1 4.8 8.1 8.8 4.5 8.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Prefoldin_2 PF01920.20 EGO53385.1 - 9.3e-23 80.2 2.7 1.2e-22 79.9 2.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF3683 PF12447.8 EGO53385.1 - 0.015 15.5 0.3 0.04 14.0 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3683) Mst1_SARAH PF11629.8 EGO53385.1 - 0.064 13.3 0.7 0.2 11.8 0.0 2.1 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 DUF3450 PF11932.8 EGO53385.1 - 0.074 12.3 5.9 2.3 7.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 EGO53385.1 - 0.079 13.5 1.9 0.68 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 Dynamin_M PF01031.20 EGO53385.1 - 0.08 12.1 2.3 0.15 11.2 0.1 1.9 2 0 0 2 2 2 0 Dynamin central region ADIP PF11559.8 EGO53385.1 - 0.39 10.8 8.8 5.4 7.1 0.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.6 EGO53385.1 - 0.42 11.0 6.8 3 8.3 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.10 EGO53385.1 - 0.65 10.2 4.4 0.97 9.6 0.2 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 EGO53385.1 - 1.1 9.7 4.5 0.55 10.7 1.4 2.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Swi5 PF07061.11 EGO53385.1 - 1.1 9.4 8.9 2 8.5 1.4 2.1 2 0 0 2 2 2 0 Swi5 DUF2730 PF10805.8 EGO53385.1 - 1.7 8.8 4.8 16 5.7 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) XhlA PF10779.9 EGO53385.1 - 2.1 8.6 5.7 0.54 10.5 1.5 2.1 2 1 0 2 2 2 0 Haemolysin XhlA bZIP_1 PF00170.21 EGO53385.1 - 4.7 7.4 8.7 0.33 11.1 2.4 2.1 2 1 1 3 3 3 0 bZIP transcription factor Mito_carr PF00153.27 EGO53388.1 - 1.3e-48 162.8 2.2 8.9e-17 60.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Dor1 PF04124.12 EGO53389.1 - 2.3e-84 283.0 1.9 1.3e-78 264.1 0.3 3.0 2 1 1 3 3 3 3 Dor1-like family TRAM_LAG1_CLN8 PF03798.16 EGO53391.1 - 8.8e-53 179.0 16.2 1.4e-52 178.3 16.2 1.3 1 0 0 1 1 1 1 TLC domain LYRIC PF15686.5 EGO53391.1 - 0.055 13.0 0.1 0.08 12.5 0.1 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family SH3_1 PF00018.28 EGO53392.1 - 1.5e-36 123.7 7.3 8e-13 47.8 0.3 4.5 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 EGO53392.1 - 6.6e-36 122.0 0.1 1.2e-35 121.2 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 EGO53392.1 - 3.1e-33 113.4 7.9 6.6e-12 45.1 0.1 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 EGO53392.1 - 7.6e-24 83.2 0.1 3.3e-08 33.1 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.11 EGO53392.1 - 7.8e-09 35.8 189.1 7.5e-06 26.3 59.9 5.5 2 1 3 5 5 5 3 Domain of unknown function (DUF1720) SH3_3 PF08239.11 EGO53392.1 - 0.00087 19.5 3.3 0.38 11.1 1.1 3.3 3 0 0 3 3 3 1 Bacterial SH3 domain SAM_4 PF18017.1 EGO53392.1 - 0.00088 19.2 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 EGO53392.1 - 0.0042 17.1 0.0 0.26 11.4 0.0 3.2 3 0 0 3 3 3 1 SH3 domain A_deaminase PF00962.22 EGO53393.1 - 5.2e-121 404.0 0.0 6.9e-121 403.6 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.11 EGO53394.1 - 3e-117 391.1 5.2 3.8e-117 390.8 5.2 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 EGO53394.1 - 5.3e-07 29.1 0.4 5.3e-07 29.1 0.4 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter DUF4079 PF13301.6 EGO53394.1 - 0.011 15.9 0.1 0.052 13.7 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Cytochrom_B561 PF03188.16 EGO53394.1 - 0.023 14.8 1.2 0.12 12.5 0.0 2.6 3 1 0 3 3 3 0 Eukaryotic cytochrome b561 EamA PF00892.20 EGO53394.1 - 9.6 6.4 31.3 13 5.9 11.9 3.7 2 2 1 3 3 3 0 EamA-like transporter family Sybindin PF04099.12 EGO53396.1 - 7e-56 188.1 0.0 8.8e-56 187.8 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EGO53396.1 - 1.4e-07 31.7 0.1 2.1e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region VWA_2 PF13519.6 EGO53397.1 - 5.4e-24 84.9 0.4 1.2e-23 83.8 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 EGO53397.1 - 3.7e-08 33.4 0.0 5.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 EGO53397.1 - 4.3e-08 33.6 0.3 5.8e-08 33.2 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DHBP_synthase PF00926.19 EGO53397.1 - 0.018 14.5 0.1 6.2 6.3 0.0 2.6 2 1 1 3 3 3 0 3,4-dihydroxy-2-butanone 4-phosphate synthase UIM PF02809.20 EGO53397.1 - 0.021 14.7 1.1 0.021 14.7 1.1 2.9 3 0 0 3 3 3 0 Ubiquitin interaction motif DNA_pol3_a_NII PF11490.8 EGO53397.1 - 1.2 9.1 6.3 0.35 10.8 2.2 2.0 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Nbl1_Borealin_N PF10444.9 EGO53398.1 - 1.2e-20 72.9 3.0 2.1e-20 72.1 3.0 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal SUI1 PF01253.22 EGO53399.1 - 7.5e-25 87.3 0.4 7.5e-25 87.3 0.4 1.7 2 0 0 2 2 2 1 Translation initiation factor SUI1 TnpV PF14198.6 EGO53399.1 - 0.0036 17.2 0.9 0.0061 16.5 0.9 1.3 1 0 0 1 1 1 1 Transposon-encoded protein TnpV R3H-assoc PF13902.6 EGO53399.1 - 0.049 14.0 2.4 0.072 13.5 2.4 1.3 1 0 0 1 1 1 0 R3H-associated N-terminal domain Img2 PF05046.14 EGO53399.1 - 0.08 13.2 0.3 0.2 12.0 0.1 1.8 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) SAB PF04382.13 EGO53400.1 - 0.057 13.5 0.1 0.088 12.9 0.1 1.3 1 0 0 1 1 1 0 SAB domain Methyltransf_11 PF08241.12 EGO53401.1 - 8.5e-14 52.0 0.0 2.1e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO53401.1 - 3e-05 24.6 0.0 7e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO53401.1 - 0.0077 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO53401.1 - 0.02 15.7 0.0 0.058 14.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EGO53401.1 - 0.044 13.1 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGO53401.1 - 0.051 13.4 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain MIase PF02426.16 EGO53401.1 - 0.12 12.6 0.2 6.1 7.1 0.0 3.6 3 0 0 3 3 3 0 Muconolactone delta-isomerase Spore_III_AE PF09546.10 EGO53403.1 - 0.067 12.4 0.2 0.099 11.8 0.2 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) Zn_clus PF00172.18 EGO53404.1 - 0.062 13.4 6.0 0.23 11.6 6.0 2.0 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EGO53404.1 - 0.46 11.0 23.6 1.8 9.2 0.2 6.6 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO53404.1 - 3 8.9 23.6 1.2 10.1 0.1 6.8 6 1 0 6 6 6 0 C2H2-type zinc finger RNA_bind PF08675.11 EGO53406.1 - 0.021 14.8 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain Metallophos PF00149.28 EGO53407.1 - 7.3e-12 46.2 1.1 7.3e-12 46.2 1.1 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Nop14 PF04147.12 EGO53407.1 - 1.7 6.8 29.2 0.031 12.5 18.5 2.1 2 0 0 2 2 2 0 Nop14-like family Polysacc_deac_1 PF01522.21 EGO53408.1 - 7.3e-24 84.0 0.0 1.3e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 EGO53408.1 - 0.026 13.7 0.0 0.087 12.0 0.0 1.8 3 0 0 3 3 3 0 Divergent polysaccharide deacetylase Glycos_transf_2 PF00535.26 EGO53408.1 - 0.21 11.4 0.0 7.4 6.3 0.0 2.6 2 1 1 3 3 3 0 Glycosyl transferase family 2 QRPTase_C PF01729.19 EGO53409.1 - 1.9e-54 183.9 0.1 2.4e-54 183.7 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EGO53409.1 - 5.2e-19 68.1 0.0 2.1e-18 66.2 0.0 2.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Peripla_BP_6 PF13458.6 EGO53409.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein IGPS PF00218.21 EGO53409.1 - 0.11 11.6 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Glyco_hydro_61 PF03443.14 EGO53412.1 - 6.1e-54 183.1 1.3 7.4e-54 182.8 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RCC1 PF00415.18 EGO53413.1 - 8.8e-35 119.1 22.4 1.1e-05 25.9 0.0 8.9 7 3 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGO53413.1 - 2.2e-30 103.8 26.0 4.7e-09 35.8 1.9 6.7 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Microvir_J PF04726.13 EGO53413.1 - 0.19 11.7 1.0 0.39 10.7 0.3 1.8 2 0 0 2 2 2 0 Microvirus J protein PAN_4 PF14295.6 EGO53415.1 - 0.0028 17.5 2.4 0.0062 16.4 2.4 1.5 1 0 0 1 1 1 1 PAN domain Transket_pyr PF02779.24 EGO53416.1 - 7.5e-44 149.5 0.0 1.1e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGO53416.1 - 1.8e-34 118.3 0.0 5.4e-34 116.8 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Aminotran_5 PF00266.19 EGO53416.1 - 0.017 14.1 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Sterol_MT_C PF08498.10 EGO53418.1 - 9e-27 93.2 0.9 1.5e-26 92.5 0.9 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EGO53418.1 - 9.1e-22 77.5 0.0 2e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO53418.1 - 2.4e-19 69.8 0.0 5.6e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO53418.1 - 1.4e-17 63.9 0.0 2.3e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO53418.1 - 1.2e-10 42.1 0.0 3.1e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO53418.1 - 2.6e-10 40.4 0.0 4.3e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO53418.1 - 1.3e-09 37.8 0.0 2.3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EGO53418.1 - 9.3e-09 35.0 0.1 1.3e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 EGO53418.1 - 0.00017 20.3 0.0 0.00025 19.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 EGO53418.1 - 0.0014 18.1 0.1 0.02 14.3 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGO53418.1 - 0.002 17.7 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 EGO53418.1 - 0.005 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.20 EGO53418.1 - 0.008 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EGO53418.1 - 0.0096 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 EGO53418.1 - 0.017 14.7 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.18 EGO53418.1 - 0.024 13.9 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 EGO53418.1 - 0.13 12.2 0.3 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain RRM_1 PF00076.22 EGO53419.1 - 1.7e-09 37.4 0.0 3.5e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGO53419.1 - 0.0004 20.3 0.1 0.00079 19.4 0.1 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGO53419.1 - 0.0032 17.5 0.0 0.007 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif RRM_occluded PF16842.5 EGO53419.1 - 0.0033 17.3 0.0 0.0054 16.6 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_8 PF11835.8 EGO53419.1 - 0.57 10.4 2.3 0.71 10.1 0.0 2.1 2 1 0 2 2 2 0 RRM-like domain RAC_head PF16717.5 EGO53420.1 - 3.3e-32 111.3 3.2 3.3e-32 111.3 3.2 3.3 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 EGO53420.1 - 3.1e-19 68.8 0.7 1.4e-18 66.7 0.7 2.2 1 0 0 1 1 1 1 DnaJ domain TraH PF06122.11 EGO53420.1 - 0.57 9.4 5.3 0.98 8.6 5.3 1.3 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein AMP-binding PF00501.28 EGO53421.1 - 3.3e-74 250.0 0.0 5.4e-74 249.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EGO53421.1 - 2.3e-70 236.7 0.0 3.7e-70 236.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EGO53421.1 - 1.7e-10 41.1 0.0 6.2e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.21 EGO53421.1 - 2.6e-10 40.2 0.0 5.8e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO53421.1 - 1.5e-08 34.0 0.2 4.8e-08 32.3 0.2 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EGO53421.1 - 2.4e-05 25.2 0.0 0.00027 21.9 0.0 2.9 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 EGO53421.1 - 0.0067 15.6 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGO53421.1 - 0.0069 16.3 0.3 0.04 13.8 0.3 2.3 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGO53421.1 - 0.02 14.3 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGO53421.1 - 0.027 13.6 0.0 0.12 11.4 0.0 1.9 1 1 0 1 1 1 0 RmlD substrate binding domain Aminotran_5 PF00266.19 EGO53422.1 - 6.1e-16 58.3 0.0 6.3e-11 41.8 0.0 3.8 2 2 0 2 2 2 2 Aminotransferase class-V Melittin PF01372.17 EGO53422.1 - 0.047 13.6 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Melittin YafQ_toxin PF15738.5 EGO53423.1 - 0.23 11.8 0.0 0.31 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin of type II toxin-antitoxin system, YafQ Sod_Cu PF00080.20 EGO53424.1 - 2.9e-14 53.4 0.2 4.7e-14 52.8 0.1 1.3 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HET PF06985.11 EGO53426.1 - 2e-26 93.1 0.0 4.6e-26 91.9 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PIN_8 PF18476.1 EGO53426.1 - 0.23 11.3 0.5 2.2 8.1 0.1 2.2 2 0 0 2 2 2 0 PIN like domain UbiA PF01040.18 EGO53427.1 - 4.2e-07 29.5 6.2 4.2e-07 29.5 6.2 1.9 1 1 1 2 2 2 1 UbiA prenyltransferase family Spo7 PF03907.13 EGO53427.1 - 0.097 12.1 0.8 6.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Spo7-like protein DDHD PF02862.17 EGO53428.1 - 0.035 14.3 1.9 1.7 8.7 0.0 2.1 2 0 0 2 2 2 0 DDHD domain DUF3886 PF13025.6 EGO53428.1 - 0.27 11.4 30.8 0.26 11.5 7.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) CENP-N PF05238.13 EGO53428.1 - 0.99 8.6 11.8 1.4 8.2 0.2 2.1 2 0 0 2 2 2 0 Kinetochore protein CHL4 like Folate_carrier PF01770.18 EGO53428.1 - 1.3 7.7 2.5 1.3 7.6 0.0 1.8 2 0 0 2 2 2 0 Reduced folate carrier ANAPC4_WD40 PF12894.7 EGO53429.1 - 0.00015 22.0 0.0 4.5 7.6 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO53429.1 - 0.0091 16.8 0.9 6 7.9 0.2 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF4602 PF15375.6 EGO53429.1 - 0.58 10.5 9.0 0.065 13.6 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) Indigoidine_A PF04227.12 EGO53431.1 - 3.5e-112 374.5 1.0 5.7e-112 373.8 1.0 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 EGO53431.1 - 4.9e-26 91.7 0.4 5.7e-15 55.4 0.0 3.1 3 0 0 3 3 3 2 pfkB family carbohydrate kinase HTH_DeoR PF08220.12 EGO53431.1 - 0.038 13.8 0.0 0.16 11.8 0.0 2.1 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Arrestin_N PF00339.29 EGO53432.1 - 7.9e-12 45.5 0.0 3.3e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EGO53432.1 - 5.4e-05 23.7 0.0 0.00015 22.3 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain F-box-like PF12937.7 EGO53433.1 - 0.00066 19.5 0.5 0.0014 18.5 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO53433.1 - 0.0014 18.5 1.0 0.003 17.4 1.0 1.5 1 0 0 1 1 1 1 F-box domain FSA_C PF10479.9 EGO53433.1 - 0.27 9.3 0.4 0.4 8.7 0.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 EGO53433.1 - 0.84 9.6 14.4 1.8 8.6 14.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Spt5_N PF11942.8 EGO53433.1 - 2.4 9.2 10.8 4.8 8.2 10.8 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal FAD_binding_3 PF01494.19 EGO53434.1 - 1.5e-75 254.6 0.0 1.9e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGO53434.1 - 8.4e-29 100.7 0.0 1.5e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EGO53434.1 - 5.2e-07 29.2 0.0 0.00022 20.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO53434.1 - 2.7e-05 24.6 0.0 0.0021 18.6 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO53434.1 - 0.00017 20.5 0.1 0.00032 19.5 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EGO53434.1 - 0.0014 18.8 0.1 0.0036 17.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGO53434.1 - 0.011 14.8 0.2 0.027 13.5 0.2 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 EGO53434.1 - 0.016 14.8 0.0 0.24 10.9 0.0 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGO53434.1 - 0.03 13.2 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 EGO53434.1 - 0.041 13.1 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EGO53434.1 - 0.08 12.0 0.1 0.14 11.2 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EGO53434.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EGO53434.1 - 0.14 11.4 0.1 0.27 10.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Vps53_N PF04100.12 EGO53435.1 - 2.1e-102 342.9 0.1 3.6e-102 342.2 0.1 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Sec6 PF06046.13 EGO53435.1 - 2.1e-06 26.4 0.0 9e-05 21.0 0.0 2.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps54_N PF10475.9 EGO53435.1 - 1.8e-05 24.2 3.6 3.5e-05 23.2 3.6 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EGO53435.1 - 4e-05 23.5 0.1 0.00011 22.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) RINT1_TIP1 PF04437.13 EGO53435.1 - 0.00034 19.6 0.6 0.019 13.9 0.0 2.8 3 0 0 3 3 3 1 RINT-1 / TIP-1 family Zw10 PF06248.13 EGO53435.1 - 0.00089 17.9 2.0 0.0015 17.2 2.0 1.2 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Spc7 PF08317.11 EGO53435.1 - 0.0028 16.6 1.1 0.0059 15.5 1.1 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein FliG_N PF14842.6 EGO53435.1 - 0.016 15.8 0.2 0.074 13.6 0.2 2.2 1 0 0 1 1 1 0 FliG N-terminal domain DUF1664 PF07889.12 EGO53435.1 - 0.026 14.6 0.4 0.11 12.5 0.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EGO53435.1 - 0.033 14.2 0.3 0.13 12.3 0.3 2.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec15 PF04091.12 EGO53435.1 - 0.077 12.4 0.1 0.19 11.1 0.1 1.6 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like APG6_N PF17675.1 EGO53435.1 - 0.18 12.3 3.7 0.23 12.0 2.1 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Snf7 PF03357.21 EGO53435.1 - 1 8.9 4.8 2.6 7.6 4.8 1.7 1 1 0 1 1 1 0 Snf7 Nup54 PF13874.6 EGO53435.1 - 2.1 8.5 6.4 5.3 7.2 6.4 1.8 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4164 PF13747.6 EGO53435.1 - 5.4 7.4 8.3 6.2 7.2 2.9 3.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4164) CAP_N PF01213.19 EGO53435.1 - 6.9 6.1 8.0 4.7 6.6 4.2 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Glyco_hydro_18 PF00704.28 EGO53436.1 - 1.3e-59 202.5 0.0 1.4e-59 202.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Methyltransf_34 PF11312.8 EGO53436.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase ubiquitin PF00240.23 EGO53438.1 - 3.8e-17 61.8 0.2 5.1e-17 61.4 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EGO53438.1 - 2.2e-06 27.4 0.8 5.7e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 EGO53438.1 - 7.1e-06 25.8 0.2 1.1e-05 25.2 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGO53438.1 - 0.004 17.7 0.0 0.0069 16.9 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGO53438.1 - 0.008 16.3 0.1 0.014 15.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 EGO53438.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair DUF3446 PF11928.8 EGO53438.1 - 1.5 9.1 8.9 4.4 7.7 0.6 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain STI1 PF17830.1 EGO53438.1 - 3.6 7.6 17.0 0.056 13.4 3.5 2.9 3 0 0 3 3 3 0 STI1 domain UPF0154 PF03672.13 EGO53438.1 - 5.1 7.2 9.5 6.3 6.9 0.2 3.7 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0154) NPR2 PF06218.11 EGO53439.1 - 4.5e-109 365.1 0.0 3e-64 217.4 0.0 2.7 2 1 0 2 2 2 2 Nitrogen permease regulator 2 tRNA-synt_1b PF00579.25 EGO53440.1 - 2.3e-91 306.2 0.1 1.5e-90 303.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EGO53440.1 - 1.5e-45 153.8 0.0 4.4e-45 152.4 0.0 1.8 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain Exog_C PF18026.1 EGO53440.1 - 0.079 13.0 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain ERO1 PF04137.15 EGO53440.1 - 0.26 10.4 2.8 0.47 9.6 2.8 1.3 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF3198 PF11433.8 EGO53440.1 - 0.36 10.7 2.4 0.25 11.3 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) CybS PF05328.12 EGO53441.1 - 3.1e-51 172.6 0.0 3.7e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit DUF3419 PF11899.8 EGO53442.1 - 1.7e-155 517.9 0.0 2.6e-155 517.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 EGO53442.1 - 1.6e-12 47.6 0.0 6.8e-11 42.3 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO53442.1 - 2.4e-07 31.4 0.0 2e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO53442.1 - 7.4e-07 29.1 0.0 2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO53442.1 - 2.2e-06 28.3 0.0 1.4e-05 25.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO53442.1 - 2.5e-06 28.0 0.0 5.7e-05 23.7 0.0 3.1 4 0 0 4 4 4 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO53442.1 - 2.6e-05 23.7 0.1 0.0017 17.7 0.0 2.6 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EGO53442.1 - 0.00079 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EGO53442.1 - 0.046 13.2 0.0 0.39 10.2 0.0 2.4 3 0 0 3 3 3 0 Putative methyltransferase CBFB_NFYA PF02045.15 EGO53443.1 - 1.7e-28 99.0 5.1 3.5e-28 98.0 5.1 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 EGO53443.1 - 0.012 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein SDA1 PF05285.12 EGO53448.1 - 3.4e-05 23.5 3.0 3.5e-05 23.4 3.0 1.1 1 0 0 1 1 1 1 SDA1 PPP4R2 PF09184.11 EGO53448.1 - 0.053 13.1 13.6 0.086 12.4 13.6 1.2 1 0 0 1 1 1 0 PPP4R2 HNF-1_N PF04814.13 EGO53448.1 - 2.7 8.6 9.1 2 9.0 7.0 1.7 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus VRR_NUC PF08774.11 EGO53449.1 - 3.8e-24 84.8 0.1 4.3e-23 81.4 0.0 2.4 2 0 0 2 2 2 1 VRR-NUC domain Dpy-30 PF05186.13 EGO53450.1 - 1.6e-13 50.1 0.0 1.6e-13 50.1 0.0 1.6 2 0 0 2 2 2 1 Dpy-30 motif Ribosomal_S13_N PF08069.12 EGO53451.1 - 1.3e-31 108.4 0.3 2.2e-31 107.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EGO53451.1 - 2.2e-15 56.6 0.2 3.2e-15 56.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 EGO53451.1 - 0.022 14.7 0.1 0.056 13.4 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain HOIP-UBA PF16678.5 EGO53451.1 - 0.068 13.2 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 HOIP UBA domain pair RRM_1 PF00076.22 EGO53452.1 - 1.3e-30 105.0 0.0 2.6e-13 49.6 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO53452.1 - 1.2e-05 25.1 0.3 0.64 9.9 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif OGG_N PF07934.12 EGO53453.1 - 6.9e-14 52.0 0.2 1.9e-13 50.6 0.1 1.7 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EGO53453.1 - 1.1e-13 51.5 0.0 2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGO53453.1 - 0.035 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif HECT_2 PF09814.9 EGO53454.1 - 5.3e-103 344.8 0.1 6.1e-103 344.6 0.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding SF3b1 PF08920.10 EGO53455.1 - 1.5e-24 86.8 9.1 1.5e-24 86.8 9.1 2.5 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 EGO53455.1 - 1.2e-12 48.0 3.0 0.016 15.7 0.0 7.6 7 1 1 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.6 EGO53455.1 - 4.6e-10 39.8 12.3 0.1 13.0 0.1 8.2 6 3 5 11 11 10 4 HEAT repeats HEAT PF02985.22 EGO53455.1 - 7.5e-09 35.1 9.8 0.74 10.2 0.0 9.0 10 0 0 10 10 9 3 HEAT repeat Vac14_Fab1_bd PF12755.7 EGO53455.1 - 1.1e-05 26.0 0.5 1.1 9.9 0.0 5.3 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EGO53455.1 - 5.6e-05 23.1 1.7 0.0048 16.8 0.0 4.5 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) Adaptin_N PF01602.20 EGO53455.1 - 5.8e-05 21.8 0.3 0.019 13.5 0.0 3.1 2 2 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.12 EGO53455.1 - 0.00013 21.7 0.5 0.95 9.1 0.0 4.4 4 2 0 5 5 5 2 NUC173 domain CLASP_N PF12348.8 EGO53455.1 - 0.0081 15.8 0.1 1.8 8.0 0.0 3.6 4 0 0 4 4 4 1 CLASP N terminal UNC45-central PF11701.8 EGO53455.1 - 0.0088 16.0 0.0 0.032 14.2 0.0 1.9 2 0 0 2 2 1 1 Myosin-binding striated muscle assembly central DRIM PF07539.12 EGO53455.1 - 0.02 13.2 0.5 3.4 5.9 0.0 3.8 2 1 2 4 4 4 0 Down-regulated in metastasis Opi1 PF08618.10 EGO53455.1 - 0.4 9.9 2.7 0.82 8.9 2.7 1.4 1 0 0 1 1 1 0 Transcription factor Opi1 zf-C2H2 PF00096.26 EGO53456.1 - 2.6e-09 37.0 12.3 2.3e-05 24.6 4.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO53456.1 - 4.3e-09 36.4 14.5 2.7e-05 24.4 0.6 3.3 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO53456.1 - 1.5e-06 28.5 11.7 0.0013 19.3 3.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGO53456.1 - 4.6e-06 26.5 7.2 0.00012 21.9 2.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EGO53456.1 - 5e-06 26.7 1.6 1.7e-05 25.0 1.2 2.2 1 1 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGO53456.1 - 0.00097 19.4 2.1 0.00097 19.4 2.1 2.5 2 1 1 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EGO53456.1 - 0.037 13.9 2.6 2.7 8.0 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 EGO53456.1 - 0.041 14.2 1.8 0.57 10.5 0.2 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 EGO53456.1 - 0.079 13.3 3.6 0.089 13.1 2.1 1.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 EGO53456.1 - 0.89 9.4 9.3 3.8 7.4 0.3 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type Rax2 PF12768.7 EGO53459.1 - 4.7e-75 251.7 0.1 4.4e-72 242.0 0.0 4.2 4 1 1 5 5 5 1 Cortical protein marker for cell polarity Kelch_6 PF13964.6 EGO53459.1 - 1.2e-05 25.4 4.6 1.5 9.2 0.0 6.2 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 EGO53459.1 - 0.0012 18.8 2.3 0.044 13.8 0.1 3.4 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.25 EGO53459.1 - 0.021 14.4 1.1 0.054 13.1 0.1 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.15 EGO53459.1 - 0.023 14.7 3.5 0.58 10.2 0.0 4.1 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.6 EGO53459.1 - 1.5 9.2 16.1 0.28 11.5 0.4 4.8 6 0 0 6 6 6 0 Galactose oxidase, central domain PQQ_3 PF13570.6 EGO53459.1 - 2.2 8.9 24.3 1.5 9.4 0.1 6.7 7 1 0 7 7 7 0 PQQ-like domain SNase PF00565.17 EGO53461.1 - 2.1e-22 79.6 0.4 4.1e-22 78.7 0.0 1.6 2 0 0 2 2 2 1 Staphylococcal nuclease homologue Med9 PF07544.13 EGO53463.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 HAD PF12710.7 EGO53464.1 - 1.4e-12 48.4 0.1 8.5e-12 45.9 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGO53464.1 - 1.9e-05 24.9 0.1 0.24 11.4 0.0 3.1 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGO53464.1 - 0.0016 18.7 0.1 0.036 14.4 0.1 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EGO53464.1 - 0.064 12.6 0.0 0.64 9.4 0.0 2.1 2 0 0 2 2 2 0 Putative Phosphatase TFIIF_beta_N PF17683.1 EGO53465.1 - 7.7e-28 97.9 0.1 1.4e-27 97.0 0.1 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 EGO53465.1 - 4.1e-26 90.9 0.0 7.2e-26 90.1 0.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 EGO53465.1 - 0.013 16.3 2.5 0.032 15.0 2.5 1.8 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain zf-CCCH PF00642.24 EGO53466.1 - 1.8e-05 24.5 15.2 0.13 12.2 0.0 5.2 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGO53466.1 - 0.00044 20.0 14.0 0.03 14.1 0.0 4.7 5 0 0 5 5 5 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EGO53466.1 - 0.0015 18.7 11.4 0.005 17.0 1.0 3.0 1 1 1 2 2 2 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 EGO53466.1 - 0.0048 16.9 22.2 0.17 12.0 3.6 5.7 5 1 0 5 5 5 3 Zinc finger domain Torus PF16131.5 EGO53466.1 - 9.5 7.0 14.7 18 6.0 0.3 4.1 1 1 3 4 4 4 0 Torus domain Pyr_redox_3 PF13738.6 EGO53467.1 - 4.3e-08 32.8 0.0 0.013 14.7 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO53467.1 - 1.2e-07 31.6 0.1 2.2e-06 27.5 0.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FMO-like PF00743.19 EGO53467.1 - 3.5e-07 29.0 0.2 0.0005 18.6 0.0 2.9 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EGO53467.1 - 1.2e-06 27.9 0.0 0.0031 16.7 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EGO53467.1 - 2.2e-06 27.1 0.1 0.13 11.4 0.3 3.0 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO53467.1 - 0.00017 21.6 0.5 0.024 14.6 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.22 EGO53467.1 - 0.00056 19.1 0.2 0.3 10.1 0.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 EGO53467.1 - 0.00076 18.8 0.3 0.0045 16.2 0.1 2.2 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.6 EGO53467.1 - 0.0021 18.2 0.0 0.0056 16.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGO53467.1 - 0.079 13.5 0.2 1.7 9.3 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO53467.1 - 0.12 11.1 0.6 0.32 9.7 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 EGO53467.1 - 0.12 11.4 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Malic_M PF03949.15 EGO53467.1 - 0.18 11.1 0.0 6.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain DUF5601 PF18151.1 EGO53467.1 - 0.19 12.1 0.0 0.35 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) Shikimate_DH PF01488.20 EGO53467.1 - 0.21 11.7 0.0 18 5.4 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase P34-Arc PF04045.14 EGO53468.1 - 3.6e-105 351.0 0.3 4.4e-105 350.7 0.3 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc WD40 PF00400.32 EGO53469.1 - 7.8e-48 159.5 20.4 1.3e-05 25.8 0.3 12.3 12 1 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.12 EGO53469.1 - 9.3e-20 70.9 0.1 2.4e-19 69.6 0.1 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EGO53469.1 - 6.7e-17 61.6 8.7 0.016 15.5 0.1 8.6 6 2 5 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGO53469.1 - 5.7e-05 22.6 0.2 2.7 7.2 0.0 3.7 3 1 1 4 4 4 2 WD40-like domain Nup160 PF11715.8 EGO53469.1 - 0.00038 19.3 0.1 0.24 10.0 0.0 4.4 3 1 1 5 5 5 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGO53469.1 - 0.00067 18.7 2.9 0.35 9.8 0.0 4.7 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EGO53469.1 - 0.00097 18.0 1.9 0.074 11.8 0.1 3.6 3 1 0 4 4 4 1 Nup133 N terminal like Frtz PF11768.8 EGO53469.1 - 0.0045 15.4 0.0 0.36 9.1 0.0 2.6 2 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 EGO53469.1 - 0.05 13.5 0.2 1.6 8.6 0.0 3.8 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A TFIIF_alpha PF05793.12 EGO53471.1 - 1.7 7.1 31.8 2.6 6.5 31.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MSP1a PF11670.8 EGO53471.1 - 3.4 6.9 6.7 8.4 5.6 6.7 1.6 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) MCM_bind PF09739.9 EGO53471.1 - 8.8 4.6 14.8 16 3.8 14.8 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Cwf_Cwc_15 PF04889.12 EGO53471.1 - 9.2 5.9 29.8 16 5.1 29.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sel1 PF08238.12 EGO53472.1 - 1.3e-16 60.6 6.4 2.3e-05 24.9 0.0 4.5 4 0 0 4 4 4 3 Sel1 repeat Steroid_dh PF02544.16 EGO53473.1 - 0.66 10.0 9.2 1.6 8.7 0.1 2.6 3 0 0 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase bZIP_1 PF00170.21 EGO53474.1 - 1.7e-08 34.4 13.3 1.7e-08 34.4 13.3 2.9 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 EGO53474.1 - 4.2e-08 33.6 13.5 1.5e-07 31.8 13.5 2.0 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 EGO53474.1 - 5.4e-05 23.2 11.3 5.4e-05 23.2 11.3 3.1 1 1 3 4 4 4 1 Basic region leucine zipper KASH_CCD PF14662.6 EGO53474.1 - 0.022 14.6 17.6 0.044 13.6 17.6 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH MCU PF04678.13 EGO53474.1 - 0.74 9.9 12.9 4 7.5 0.0 3.0 2 1 1 3 3 3 0 Mitochondrial calcium uniporter FapA PF03961.13 EGO53474.1 - 0.75 8.3 12.6 1.2 7.7 12.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Jnk-SapK_ap_N PF09744.9 EGO53474.1 - 1.4 9.2 20.3 3.1 8.0 20.3 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 EGO53474.1 - 1.8 8.6 20.1 3.5 7.7 20.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 EGO53474.1 - 3.7 7.0 11.1 7.6 6.0 11.1 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EGO53474.1 - 6.7 4.5 7.9 11 3.8 7.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CBF PF03914.17 EGO53476.1 - 4.9e-33 114.6 2.4 8.6e-33 113.8 0.1 2.6 3 1 1 4 4 4 1 CBF/Mak21 family LemA PF04011.12 EGO53476.1 - 0.024 14.5 0.4 0.062 13.1 0.4 1.6 1 0 0 1 1 1 0 LemA family Syntaxin-18_N PF10496.9 EGO53476.1 - 0.031 14.5 1.8 0.35 11.2 1.5 2.8 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus Phage_GP20 PF06810.11 EGO53476.1 - 0.1 12.4 7.5 0.1 12.4 5.7 1.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF3201 PF11447.8 EGO53476.1 - 0.11 12.1 3.6 22 4.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3201) Baculo_F PF12259.8 EGO53476.1 - 0.17 10.4 0.5 0.29 9.6 0.5 1.3 1 0 0 1 1 1 0 Baculovirus F protein Mt_ATP-synt_B PF05405.14 EGO53477.1 - 2.8e-55 186.4 5.3 3.3e-55 186.1 5.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Dak2 PF02734.17 EGO53477.1 - 0.26 11.2 3.8 0.28 11.0 2.4 1.7 1 1 0 1 1 1 0 DAK2 domain MinE PF03776.14 EGO53478.1 - 0.024 14.6 0.1 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE MTS PF05175.14 EGO53479.1 - 0.0021 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGO53479.1 - 0.09 13.5 0.0 0.15 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pkr1 PF08636.10 EGO53480.1 - 3.7e-32 110.3 6.7 4.9e-32 109.9 6.7 1.2 1 0 0 1 1 1 1 ER protein Pkr1 DUF3357 PF11837.8 EGO53480.1 - 0.4 11.1 3.2 5.3 7.6 3.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) OAD_gamma PF04277.13 EGO53480.1 - 1.8 9.2 4.7 9.8 6.8 4.7 2.1 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Cullin PF00888.22 EGO53483.1 - 5.6e-22 78.1 0.0 8.4e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 EGO53483.1 - 2.4e-20 72.8 0.3 6.4e-20 71.4 0.3 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Flg_hook PF02120.16 EGO53483.1 - 0.072 13.0 0.2 0.84 9.6 0.0 2.4 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK DUF760 PF05542.11 EGO53483.1 - 0.15 12.4 0.0 0.75 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF760) APH PF01636.23 EGO53484.1 - 1.6e-47 162.5 0.1 5.3e-47 160.8 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGO53484.1 - 6.5e-06 25.7 0.0 9.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 EGO53484.1 - 0.0018 17.9 0.0 0.42 10.2 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 EGO53484.1 - 0.0034 17.0 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EGO53484.1 - 0.014 14.6 0.0 0.59 9.3 0.0 2.3 1 1 0 1 1 1 0 Fructosamine kinase DUF1679 PF07914.11 EGO53484.1 - 0.13 11.1 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 EGO53484.1 - 0.21 10.9 0.0 7.5 5.8 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain BNR_6 PF15899.5 EGO53485.1 - 0.13 12.4 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 BNR-Asp box repeat SOXp PF12336.8 EGO53487.1 - 0.15 13.1 0.0 0.17 13.0 0.0 1.2 1 0 0 1 1 1 0 SOX transcription factor Rad17 PF03215.15 EGO53488.1 - 5.3e-25 88.4 0.0 9.7e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EGO53488.1 - 0.00067 19.9 0.0 0.0021 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGO53488.1 - 0.0015 18.2 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO53488.1 - 0.0023 18.4 0.0 0.0074 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EGO53488.1 - 0.015 15.7 0.0 0.051 14.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF853 PF05872.12 EGO53488.1 - 0.02 13.5 0.0 0.041 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_28 PF13521.6 EGO53488.1 - 0.046 14.0 0.0 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGO53488.1 - 0.059 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGO53488.1 - 0.066 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 EGO53488.1 - 0.09 12.8 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 EGO53488.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Questin_oxidase PF14027.6 EGO53489.1 - 7.2e-90 301.9 0.6 8.7e-90 301.7 0.6 1.1 1 0 0 1 1 1 1 Questin oxidase-like TTc_toxin_rep PF18807.1 EGO53489.1 - 0.34 10.8 2.2 3.9 7.4 2.2 2.3 1 1 0 1 1 1 0 Tripartite Tc toxins repeat Ribul_P_3_epim PF00834.19 EGO53490.1 - 1.6e-62 210.5 0.0 7.4e-62 208.3 0.0 1.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 EGO53490.1 - 0.02 14.2 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 EGO53490.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.19 EGO53490.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Ofd1_CTDD PF10637.9 EGO53491.1 - 1.5e-99 332.5 0.1 3.4e-94 315.0 0.1 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EGO53491.1 - 1.6e-25 89.6 0.0 6.6e-25 87.6 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EGO53491.1 - 1.9e-12 47.9 0.0 4e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1963 PF09234.10 EGO53491.1 - 0.021 15.3 0.1 0.067 13.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) Cys_Met_Meta_PP PF01053.20 EGO53493.1 - 2.6e-58 197.4 0.0 6.2e-58 196.2 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ank_5 PF13857.6 EGO53494.1 - 0.1 12.9 0.1 0.27 11.6 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) SIR2 PF02146.17 EGO53495.1 - 1.9e-56 190.7 0.0 2.8e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EGO53495.1 - 0.006 16.3 0.0 0.1 12.4 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain zf-LYAR PF08790.11 EGO53495.1 - 0.087 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Cu-oxidase_3 PF07732.15 EGO53498.1 - 1.3e-43 147.8 3.8 4.4e-41 139.6 0.2 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGO53498.1 - 4.5e-36 123.6 6.4 3.1e-34 117.7 0.6 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EGO53498.1 - 3.2e-34 118.4 0.0 7.7e-34 117.1 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase Romo1 PF10247.9 EGO53499.1 - 2.3e-30 104.7 14.2 3.5e-30 104.2 14.2 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 EGO53499.1 - 0.0032 17.8 2.9 0.0037 17.6 2.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family FHA PF00498.26 EGO53500.1 - 2.2e-17 63.1 0.0 6.8e-17 61.6 0.0 1.9 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGO53500.1 - 0.00014 22.1 0.1 0.0013 19.0 0.0 2.4 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 EGO53500.1 - 0.014 15.0 0.4 0.035 13.7 0.0 1.8 2 0 0 2 2 2 0 YhfZ C-terminal domain GAS PF13851.6 EGO53500.1 - 1.1 8.6 15.3 0.034 13.5 4.0 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Vps39_1 PF10366.9 EGO53502.1 - 0.16 12.3 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 SMRP1 PF15181.6 EGO53505.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.4 1 1 0 1 1 1 0 Spermatid-specific manchette-related protein 1 Cutinase PF01083.22 EGO53506.1 - 1.2e-06 28.7 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Cutinase DUF676 PF05057.14 EGO53506.1 - 6.9e-05 22.5 0.0 7.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EGO53506.1 - 0.0016 19.1 0.0 0.0018 18.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EGO53506.1 - 0.0028 17.4 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.13 EGO53506.1 - 0.0058 16.5 0.0 0.008 16.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.8 EGO53506.1 - 0.011 15.0 0.1 0.021 14.1 0.1 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 tRNA-synt_2c PF01411.19 EGO53507.1 - 3.9e-08 32.3 0.0 4.9e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EGO53507.1 - 4.1e-06 26.8 0.6 8e-06 25.9 0.6 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Abhydrolase_1 PF00561.20 EGO53508.1 - 8.7e-48 163.2 0.0 3.2e-47 161.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EGO53508.1 - 0.00014 21.6 0.0 0.00034 20.3 0.0 1.6 1 0 0 1 1 1 1 Putative esterase zf-RING_6 PF14835.6 EGO53508.1 - 0.039 13.8 0.2 0.095 12.6 0.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein PAP_assoc PF03828.19 EGO53510.1 - 4.7e-17 61.9 0.1 1.3e-16 60.6 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EGO53510.1 - 1.9e-06 28.1 0.0 4.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF5596 PF18082.1 EGO53510.1 - 0.00072 19.3 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5596) Polbeta PF18765.1 EGO53510.1 - 0.061 13.4 0.6 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase CALM_bind PF16025.5 EGO53514.1 - 0.092 13.2 1.8 0.18 12.3 1.8 1.5 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding SLC35F PF06027.12 EGO53515.1 - 2.1e-95 319.7 22.1 2.7e-95 319.3 22.1 1.1 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EGO53515.1 - 1.3e-12 47.4 2.3 1.3e-12 47.4 2.3 1.8 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EGO53515.1 - 1.2e-07 32.0 36.3 0.00083 19.5 14.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family Ninjurin PF04923.12 EGO53515.1 - 0.13 12.2 1.5 0.85 9.6 0.0 2.6 2 1 0 2 2 2 0 Ninjurin FUSC-like PF12805.7 EGO53515.1 - 1.1 8.3 4.8 4 6.4 0.5 2.6 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS RNase_H2_suC PF08615.11 EGO53516.1 - 0.16 12.1 1.6 2.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RPN2_C PF18004.1 EGO53516.1 - 7.7 6.4 6.9 30 4.5 6.9 1.9 1 1 1 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain FtsX PF02687.21 EGO53519.1 - 3.9 8.0 19.7 2.2 8.8 2.3 3.7 3 0 0 3 3 3 0 FtsX-like permease family NUDIX PF00293.28 EGO53520.1 - 8.4e-14 51.7 0.0 1.3e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 EGO53521.1 - 9.2e-07 29.0 0.0 1.6e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain GST_N_2 PF13409.6 EGO53522.1 - 6.6e-20 71.2 0.1 2e-19 69.7 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO53522.1 - 1.1e-18 67.4 0.0 2.5e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO53522.1 - 8.2e-12 45.0 0.3 3e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO53522.1 - 4.8e-08 33.2 0.1 9.4e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO53522.1 - 0.0031 17.7 0.0 0.0062 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO53522.1 - 0.029 14.5 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGO53522.1 - 0.095 13.3 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-C3H1 PF10650.9 EGO53523.1 - 7.4e-07 28.8 1.4 1.2e-06 28.1 1.4 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain Ribosomal_L18_c PF14204.6 EGO53523.1 - 0.16 13.0 0.1 0.16 13.0 0.1 2.5 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region MerR-DNA-bind PF09278.11 EGO53523.1 - 1.4 9.5 8.3 0.89 10.1 0.3 3.2 3 0 0 3 3 3 0 MerR, DNA binding TerB_C PF15615.6 EGO53523.1 - 6.3 7.1 7.5 1.3 9.3 1.3 3.1 3 0 0 3 3 3 0 TerB-C domain Amino_oxidase PF01593.24 EGO53524.1 - 6e-27 95.0 0.1 2.6e-24 86.3 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGO53524.1 - 1.3e-13 50.9 0.1 2.9e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO53524.1 - 5.4e-11 42.3 0.2 2.2e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO53524.1 - 2.1e-09 37.4 1.6 1.6e-08 34.5 1.5 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGO53524.1 - 5.2e-06 25.4 0.3 0.0016 17.2 1.1 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EGO53524.1 - 4.1e-05 22.9 3.8 0.00011 21.5 3.2 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EGO53524.1 - 4.4e-05 23.0 0.0 0.00026 20.5 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO53524.1 - 0.00023 20.5 2.1 0.00039 19.8 2.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGO53524.1 - 0.0004 19.7 0.6 0.00089 18.6 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain MCRA PF06100.11 EGO53524.1 - 0.0036 16.2 0.0 0.63 8.8 0.0 2.1 2 0 0 2 2 2 2 MCRA family Pyr_redox PF00070.27 EGO53524.1 - 0.0048 17.4 7.2 0.035 14.7 1.3 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EGO53524.1 - 0.0049 16.5 0.7 0.011 15.4 0.7 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 EGO53524.1 - 0.014 14.7 0.5 0.024 13.9 0.5 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EGO53524.1 - 0.019 14.1 1.9 0.058 12.4 1.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EGO53524.1 - 0.024 14.6 1.1 0.052 13.5 0.3 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 EGO53524.1 - 0.14 11.2 3.3 0.14 11.3 1.9 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A YARHG PF13308.6 EGO53524.1 - 0.17 11.8 0.1 0.4 10.6 0.1 1.6 1 0 0 1 1 1 0 YARHG domain Trp_halogenase PF04820.14 EGO53524.1 - 1.1 8.1 4.4 2 7.2 1.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase RhoGAP PF00620.27 EGO53525.1 - 4.2e-48 163.0 0.0 1.1e-47 161.6 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EGO53525.1 - 1.5e-15 57.2 0.3 3.7e-15 55.9 0.3 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain OmpH PF03938.14 EGO53525.1 - 7.5e-05 23.1 6.5 0.00016 22.0 6.5 1.6 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 EGO53525.1 - 0.059 12.7 5.3 0.1 11.9 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GIDA_assoc PF13932.6 EGO53525.1 - 0.091 12.9 3.0 0.36 11.0 3.5 1.7 2 0 0 2 2 2 0 GidA associated domain TPR_MLP1_2 PF07926.12 EGO53525.1 - 6 6.9 9.4 0.8 9.8 2.9 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Semialdhyde_dhC PF02774.18 EGO53526.1 - 4.1e-40 137.8 0.0 5.8e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EGO53526.1 - 1.8e-30 105.8 0.0 6.1e-30 104.2 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EGO53526.1 - 0.0093 16.1 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 EGO53526.1 - 0.066 14.0 0.0 0.2 12.5 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.16 EGO53526.1 - 0.11 13.2 0.1 0.44 11.3 0.0 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase adh_short PF00106.25 EGO53527.1 - 7.3e-30 103.9 0.0 3.3e-15 56.1 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO53527.1 - 8.9e-22 77.8 0.0 4.8e-18 65.6 0.0 3.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO53527.1 - 4.7e-09 36.4 0.0 6e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 KR domain VanY PF02557.17 EGO53527.1 - 0.026 14.3 0.0 1.8 8.4 0.0 2.2 1 1 1 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Epimerase PF01370.21 EGO53527.1 - 0.15 11.5 0.4 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RRM_1 PF00076.22 EGO53528.1 - 5.4e-18 64.6 0.0 1.8e-13 50.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO53528.1 - 0.016 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 EGO53528.1 - 0.13 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain DNA_ligase_IV PF11411.8 EGO53528.1 - 0.15 12.2 0.1 0.32 11.2 0.1 1.4 1 0 0 1 1 1 0 DNA ligase IV Zn_clus PF00172.18 EGO53529.1 - 0.13 12.4 3.3 0.24 11.5 3.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.17 EGO53529.1 - 5.7 6.9 15.8 1 9.3 9.0 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein WD40 PF00400.32 EGO53531.1 - 8e-11 42.3 7.3 0.0043 17.9 0.1 5.6 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO53531.1 - 0.00014 22.1 0.0 3.7 7.9 0.0 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGO53531.1 - 0.0075 15.6 0.0 0.02 14.2 0.0 1.6 1 1 0 1 1 1 1 WD40-like domain PQQ_2 PF13360.6 EGO53531.1 - 0.031 13.9 0.1 0.17 11.4 0.0 2.2 3 1 0 3 3 3 0 PQQ-like domain DUF150 PF02576.17 EGO53534.1 - 0.028 14.8 0.8 4.9 7.6 0.2 2.5 2 0 0 2 2 2 0 RimP N-terminal domain LIAS_N PF16881.5 EGO53535.1 - 6.9e-18 65.0 0.0 1.5e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EGO53535.1 - 1.5e-16 61.2 0.0 2.2e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Synaptobrevin PF00957.21 EGO53536.1 - 2.5e-32 110.5 1.9 2.8e-32 110.4 1.9 1.0 1 0 0 1 1 1 1 Synaptobrevin Fzo_mitofusin PF04799.13 EGO53536.1 - 0.12 11.9 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF1035 PF06281.12 EGO53536.1 - 0.14 12.2 3.1 0.21 11.6 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) NAT PF04768.13 EGO53537.1 - 3.7e-52 176.4 0.1 6.8e-52 175.5 0.1 1.5 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 EGO53537.1 - 6e-34 117.1 0.0 1.9e-33 115.5 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EGO53537.1 - 7.9e-34 117.3 0.1 1.6e-33 116.3 0.1 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.20 EGO53537.1 - 0.0033 17.5 0.0 0.0092 16.1 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Methyltransf_3 PF01596.17 EGO53537.1 - 0.12 11.5 0.1 0.72 9.0 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase DUF2451 PF10474.9 EGO53538.1 - 0.044 13.6 0.2 0.3 10.8 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function C-terminus (DUF2451) Peptidase_A22B PF04258.13 EGO53539.1 - 3.5e-59 200.6 5.0 2.8e-40 138.6 1.5 2.2 2 0 0 2 2 2 2 Signal peptide peptidase SPP PF06550.11 EGO53539.1 - 0.0066 16.0 8.6 0.026 14.0 8.6 1.9 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease Ribosomal_60s PF00428.19 EGO53539.1 - 4.5 7.9 12.6 12 6.6 4.0 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4395 PF14340.6 EGO53539.1 - 4.7 7.6 10.8 0.16 12.3 1.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4395) Med31 PF05669.12 EGO53540.1 - 1.7e-35 120.9 0.4 2e-35 120.7 0.4 1.1 1 0 0 1 1 1 1 SOH1 TFIIS_C PF01096.18 EGO53541.1 - 3.3e-20 71.7 3.0 3.3e-20 71.7 3.0 2.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EGO53541.1 - 6.4e-12 45.1 0.2 6.4e-12 45.1 0.2 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 EGO53541.1 - 0.53 10.3 6.9 0.66 10.0 0.2 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 EGO53541.1 - 0.74 10.2 5.9 37 4.8 5.9 2.7 1 1 0 1 1 1 0 Restriction alleviation protein Lar Ank_3 PF13606.6 EGO53542.1 - 1.8e-09 37.0 0.1 0.0026 18.1 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGO53542.1 - 1.8e-09 37.9 0.0 1.3e-05 25.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO53542.1 - 6.3e-08 33.1 0.1 1.7e-06 28.5 0.1 2.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGO53542.1 - 7.3e-06 26.2 0.4 0.15 12.4 0.0 3.8 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EGO53542.1 - 2e-05 24.8 0.0 0.21 12.1 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Gar1 PF04410.14 EGO53542.1 - 0.03 14.1 1.0 0.046 13.5 1.0 1.3 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region Thaumatin PF00314.17 EGO53543.1 - 3e-67 226.4 0.9 3.8e-67 226.0 0.9 1.1 1 0 0 1 1 1 1 Thaumatin family Tryp_inh PF17983.1 EGO53543.1 - 0.42 10.7 4.0 2 8.6 4.0 2.2 1 0 0 1 1 1 0 Trypsin inhibitors 1,2 and 3 IRF-2BP1_2 PF11261.8 EGO53545.1 - 0.15 11.6 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger HSP70 PF00012.20 EGO53547.1 - 4.4e-11 41.7 0.1 1.4e-09 36.8 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EGO53547.1 - 0.033 13.0 0.1 0.18 10.6 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Hexokinase_2 PF03727.16 EGO53550.1 - 4.6e-76 255.4 0.0 6.2e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EGO53550.1 - 3e-74 249.3 0.1 4.1e-74 248.8 0.1 1.2 1 0 0 1 1 1 1 Hexokinase DUF5610 PF18433.1 EGO53550.1 - 0.022 15.2 0.0 0.048 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5610) Acetyltransf_1 PF00583.25 EGO53551.1 - 0.019 15.2 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family SUIM_assoc PF16619.5 EGO53551.1 - 0.23 11.5 7.0 1.9 8.6 0.2 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 zf_UBZ PF18439.1 EGO53552.1 - 0.43 10.2 2.6 2 8.1 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Sgf11 PF08209.11 EGO53552.1 - 1.5 8.5 7.4 0.17 11.5 3.1 1.7 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Pro_isomerase PF00160.21 EGO53553.1 - 1.6e-54 184.5 0.0 1.8e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Oxysterol_BP PF01237.18 EGO53554.1 - 4.2e-133 443.8 0.9 1.5e-132 441.9 0.0 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.7 EGO53554.1 - 8.9e-19 67.9 1.4 2.4e-09 37.7 0.1 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGO53554.1 - 1.7e-13 50.5 0.4 3.5e-06 27.2 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.29 EGO53554.1 - 1.6e-12 47.9 0.7 3.1e-12 46.9 0.7 1.5 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 EGO53554.1 - 2.6e-12 47.0 0.0 6.2e-07 29.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO53554.1 - 2.1e-11 43.0 0.1 0.00011 22.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EGO53554.1 - 2.4e-11 43.5 1.4 0.00025 21.4 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat PH_8 PF15409.6 EGO53554.1 - 1.6e-07 31.5 0.7 4.8e-07 30.0 0.7 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EGO53554.1 - 2.7e-05 24.5 2.2 8.6e-05 22.9 2.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain zf-C2H2_assoc3 PF16637.5 EGO53554.1 - 0.018 15.2 0.2 0.06 13.5 0.2 1.8 1 0 0 1 1 1 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz 4HBT_3 PF13622.6 EGO53555.1 - 1e-82 278.1 0.2 1.3e-82 277.8 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EGO53555.1 - 1.3e-21 76.9 0.0 3.2e-11 43.2 0.0 4.0 3 1 0 3 3 3 3 Acyl-CoA thioesterase 4HBT PF03061.22 EGO53555.1 - 0.0006 20.1 0.0 1 9.8 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily CYYR1 PF10873.8 EGO53555.1 - 0.054 13.9 1.0 0.089 13.2 1.0 1.3 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 ACPS PF01648.20 EGO53557.1 - 5.8e-07 29.6 0.0 8.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily FAD_binding_7 PF03441.14 EGO53558.1 - 2.5e-48 164.3 0.3 4.2e-48 163.5 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EGO53558.1 - 1.5e-20 73.9 0.0 2.5e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase 4HBT PF03061.22 EGO53560.1 - 9e-05 22.8 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily SQS_PSY PF00494.19 EGO53562.1 - 8.6e-73 245.1 0.1 1.2e-72 244.6 0.1 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF2398 PF09661.10 EGO53562.1 - 0.056 12.7 0.1 0.092 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) polyprenyl_synt PF00348.17 EGO53562.1 - 0.16 11.0 0.8 0.56 9.2 0.8 1.9 1 1 0 1 1 1 0 Polyprenyl synthetase SUR7 PF06687.12 EGO53563.1 - 2.1e-39 135.4 5.4 2.7e-39 135.0 5.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family MNSV_P7B PF06692.11 EGO53563.1 - 0.053 13.5 1.2 10 6.2 0.0 2.8 3 0 0 3 3 3 0 Melon necrotic spot virus P7B protein Claudin_2 PF13903.6 EGO53563.1 - 2 8.1 18.2 3.3 7.4 14.3 2.3 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Pkinase PF00069.25 EGO53564.1 - 6.6e-54 183.0 0.0 6.6e-51 173.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO53564.1 - 1.2e-29 103.3 0.0 3.7e-28 98.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO53564.1 - 0.00064 18.8 0.0 0.00089 18.3 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGO53564.1 - 0.0025 17.2 0.0 0.0036 16.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EGO53564.1 - 0.003 16.7 0.1 0.0052 15.9 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EGO53564.1 - 0.061 12.1 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGO53564.1 - 0.15 11.9 0.1 0.42 10.5 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Mem_trans PF03547.18 EGO53565.1 - 7.9e-50 169.3 0.0 1.3e-49 168.6 0.0 1.3 1 1 0 1 1 1 1 Membrane transport protein Putative_PNPOx PF01243.20 EGO53566.1 - 5.7e-13 48.9 0.0 3.7e-12 46.3 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EGO53566.1 - 0.00038 20.5 0.0 0.012 15.6 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase CPSase_L_D2 PF02786.17 EGO53567.1 - 4.3e-74 248.6 0.0 6.8e-74 247.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EGO53567.1 - 1.4e-37 128.1 0.0 4.1e-37 126.6 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 EGO53567.1 - 1.4e-36 125.4 0.1 5.5e-36 123.5 0.0 2.1 3 0 0 3 3 3 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 EGO53567.1 - 3.2e-16 58.9 1.5 1.2e-15 57.0 1.2 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp PF02222.22 EGO53567.1 - 1.4e-08 34.5 0.0 3.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGO53567.1 - 6.8e-08 32.3 0.2 2.4e-07 30.5 0.0 2.0 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EGO53567.1 - 3.3e-07 30.0 0.1 0.0079 16.0 0.0 3.4 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 EGO53567.1 - 2.8e-05 24.2 0.0 6.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EGO53567.1 - 0.00014 22.5 0.0 0.95 10.2 0.0 3.0 2 0 0 2 2 2 2 HlyD family secretion protein ATPgrasp_ST PF14397.6 EGO53567.1 - 0.0083 15.4 0.0 0.025 13.8 0.0 1.7 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp HlyD_D23 PF16576.5 EGO53567.1 - 0.015 14.5 0.1 3.2 6.9 0.0 2.7 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 EGO53567.1 - 0.076 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain GCV_H PF01597.19 EGO53567.1 - 0.12 12.3 0.2 0.34 10.8 0.2 1.8 1 0 0 1 1 1 0 Glycine cleavage H-protein CWC25 PF12542.8 EGO53568.1 - 1.5e-25 90.1 0.7 1.5e-25 90.1 0.7 4.3 4 2 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 EGO53568.1 - 9.5e-08 32.1 5.4 9.5e-08 32.1 5.4 4.7 5 1 2 7 7 7 1 N-terminal domain of CBF1 interacting co-repressor CIR PCI PF01399.27 EGO53569.1 - 3.6e-17 62.8 0.3 1.6e-16 60.7 0.0 2.3 3 0 0 3 3 3 1 PCI domain TPR_1 PF00515.28 EGO53569.1 - 0.019 14.7 4.0 0.88 9.5 0.7 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 EGO53569.1 - 0.025 13.9 0.1 0.057 12.7 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase ptaRNA1_toxin PF12703.7 EGO53569.1 - 0.058 13.4 0.1 0.2 11.7 0.1 1.9 1 0 0 1 1 1 0 Toxin of toxin-antitoxin type 1 system MIT PF04212.18 EGO53569.1 - 0.15 12.1 2.0 1.3 9.2 0.6 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 EGO53569.1 - 0.2 12.0 2.7 2.7 8.3 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGO53569.1 - 0.37 11.0 9.1 0.21 11.8 0.6 4.5 5 2 0 5 5 5 0 Tetratricopeptide repeat NUDIX_4 PF14815.6 EGO53570.1 - 0.013 15.5 0.0 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 NUDIX domain Peptidase_C65 PF10275.9 EGO53572.1 - 5.9e-75 251.9 0.0 1e-74 251.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain TFIIA PF03153.13 EGO53572.1 - 0.0013 18.9 3.3 0.0019 18.3 3.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit BPL_LplA_LipB PF03099.19 EGO53573.1 - 0.00036 20.5 0.0 0.00065 19.6 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Methyltrn_RNA_3 PF02598.17 EGO53574.1 - 1.6e-102 342.9 0.0 1.8e-102 342.7 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 EGO53574.1 - 0.18 12.0 0.0 1.3 9.2 0.0 2.0 2 0 0 2 2 2 0 SpoU rRNA Methylase family Thioredoxin PF00085.20 EGO53575.1 - 9.5e-25 86.6 0.0 1.3e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EGO53575.1 - 1.3e-06 28.0 0.0 2.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EGO53575.1 - 9.9e-06 26.0 0.1 6.2e-05 23.4 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EGO53575.1 - 0.00019 21.2 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGO53575.1 - 0.00047 20.4 0.0 0.16 12.3 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 EGO53575.1 - 0.00087 19.0 0.1 0.04 13.6 0.0 2.2 1 1 1 2 2 2 1 Redoxin HyaE PF07449.11 EGO53575.1 - 0.032 14.2 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 EGO53575.1 - 0.038 14.2 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 EGO53575.1 - 0.051 13.5 0.1 7.2 6.6 0.0 2.4 1 1 1 2 2 2 0 AhpC/TSA family SelK_SelG PF10961.8 EGO53575.1 - 0.13 12.9 2.5 0.19 12.3 0.0 2.1 1 1 1 2 2 2 0 Selenoprotein SelK_SelG Rsm22 PF09243.10 EGO53576.1 - 1e-32 113.5 0.0 3.7e-32 111.7 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Ras PF00071.22 EGO53577.1 - 3.4e-54 182.8 0.0 4e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO53577.1 - 1.4e-21 76.9 0.0 2.6e-21 76.0 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO53577.1 - 1.3e-09 37.7 0.0 2.7e-09 36.7 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGO53577.1 - 0.0017 17.7 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGO53577.1 - 0.0037 16.5 0.0 0.005 16.1 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 EGO53577.1 - 0.0067 15.9 0.0 0.0096 15.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGO53577.1 - 0.018 15.1 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EGO53577.1 - 0.11 13.1 0.0 0.17 12.4 0.0 1.4 1 1 0 1 1 1 0 ABC transporter TP_methylase PF00590.20 EGO53578.1 - 3.3e-45 154.7 0.7 8.2e-45 153.3 0.1 1.9 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EGO53578.1 - 7.3e-14 52.1 0.4 1.6e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 EGO53578.1 - 1.1e-10 40.8 0.1 2.1e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 EGO53578.1 - 4.1e-10 39.1 0.1 9.4e-09 34.8 0.0 2.4 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal HOASN PF14515.6 EGO53578.1 - 0.042 14.2 0.3 0.11 12.9 0.3 1.6 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices DUF295 PF03478.18 EGO53579.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF295) PHC2_SAM_assoc PF16616.5 EGO53580.1 - 3 8.7 5.6 5.8 7.8 5.6 1.6 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 RTC PF01137.21 EGO53581.1 - 3.5e-39 134.3 0.0 8.6e-39 133.0 0.0 1.6 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase ThiF PF00899.21 EGO53582.1 - 8.4e-39 133.4 0.0 1.3e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EGO53582.1 - 2.6e-05 24.5 0.0 9.4e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EGO53582.1 - 0.0049 17.1 0.0 0.019 15.2 0.0 2.0 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 EGO53582.1 - 0.01 16.3 0.0 0.028 14.9 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EGO53582.1 - 0.04 13.5 0.2 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 EGO53582.1 - 0.041 13.1 0.1 0.063 12.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Melibiase_2 PF16499.5 EGO53582.1 - 0.048 12.8 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha galactosidase A ApbA PF02558.16 EGO53582.1 - 0.18 11.4 0.1 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 EGO53583.1 - 9.3e-47 159.0 3.2 1.2e-46 158.6 2.9 1.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO53583.1 - 8.9e-43 146.5 1.1 1.1e-42 146.2 1.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO53583.1 - 4.1e-10 39.9 1.0 5.8e-10 39.4 1.0 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EGO53583.1 - 0.00031 20.7 0.1 0.0005 20.0 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EGO53583.1 - 0.002 17.6 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DFP PF04127.15 EGO53583.1 - 0.0039 17.0 0.7 0.0078 16.1 0.8 1.5 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.15 EGO53583.1 - 0.007 15.5 0.1 0.0098 15.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGO53583.1 - 0.0073 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGO53583.1 - 0.0076 15.4 0.2 0.011 14.9 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain ApbA PF02558.16 EGO53583.1 - 0.02 14.5 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EGO53583.1 - 0.033 14.5 0.1 0.068 13.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Methyltr_RsmB-F PF01189.17 EGO53583.1 - 0.056 13.1 0.1 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F 2-Hacid_dh_C PF02826.19 EGO53583.1 - 0.073 12.4 0.2 0.15 11.4 0.2 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EGO53583.1 - 0.082 12.5 0.1 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PepSY_2 PF13670.6 EGO53584.1 - 0.22 11.6 0.5 0.35 10.9 0.5 1.4 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain Lustrin_cystein PF14625.6 EGO53584.1 - 1.2 9.5 9.3 99 3.4 9.3 2.2 1 1 0 1 1 1 0 Lustrin, cysteine-rich repeated domain AMP-binding PF00501.28 EGO53585.1 - 3.1e-91 306.1 0.0 3.7e-91 305.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO53585.1 - 5.4e-18 65.7 1.8 2.7e-17 63.5 0.4 2.7 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Gly_transf_sug PF04488.15 EGO53586.1 - 5.1e-14 52.7 0.0 1.2e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif EST1_DNA_bind PF10373.9 EGO53588.1 - 2e-11 43.9 0.3 1.2e-09 38.1 0.1 2.3 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain EMC1_C PF07774.13 EGO53590.1 - 2.2e-78 262.8 0.0 3.8e-78 262.0 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EGO53590.1 - 1.7e-18 67.1 9.0 2.4e-18 66.6 3.1 2.9 4 0 0 4 4 4 1 PQQ-like domain PQQ PF01011.21 EGO53590.1 - 0.0024 17.7 2.3 6.3 6.9 0.0 4.8 6 0 0 6 6 6 2 PQQ enzyme repeat LRR_4 PF12799.7 EGO53591.1 - 2.5e-10 40.4 12.1 2.8e-08 33.9 2.7 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGO53591.1 - 1.3e-07 31.3 12.7 3.4e-07 29.9 2.4 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EGO53591.1 - 0.067 13.8 6.5 6.5 7.7 0.8 3.9 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 EGO53591.1 - 2.4 8.4 5.6 16 5.8 0.4 2.8 2 0 0 2 2 2 0 Leucine Rich repeat PHF5 PF03660.14 EGO53592.1 - 0.36 11.1 3.1 5.7 7.2 0.2 2.3 1 1 1 2 2 2 0 PHF5-like protein Phosducin PF02114.16 EGO53593.1 - 1.5e-14 53.6 0.2 2.2e-14 53.0 0.2 1.2 1 0 0 1 1 1 1 Phosducin Ribosomal_S27e PF01667.17 EGO53594.1 - 3.5e-28 97.1 7.5 4.2e-28 96.8 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 EGO53594.1 - 0.13 11.7 3.5 0.19 11.2 3.5 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zf-C2HC5 PF06221.13 EGO53594.1 - 0.47 10.5 6.5 2.7 8.0 4.3 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type RNR_inhib PF08591.10 EGO53595.1 - 4.7e-28 98.6 1.8 1e-27 97.5 0.2 2.4 2 1 1 3 3 3 1 Ribonucleotide reductase inhibitor SIP1 PF04938.12 EGO53596.1 - 3.3e-08 33.5 0.0 2.5e-05 24.1 0.0 2.8 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Raptor_N PF14538.6 EGO53597.1 - 4.4e-63 211.6 0.0 7.7e-63 210.8 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EGO53597.1 - 6e-09 36.4 4.4 6.1 7.9 0.0 7.0 6 0 0 6 6 6 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 EGO53597.1 - 7.7e-06 25.9 0.5 0.13 12.3 0.0 3.0 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.6 EGO53597.1 - 0.017 15.5 0.7 0.17 12.3 0.0 2.8 3 0 0 3 3 3 0 HEAT repeats HEAT PF02985.22 EGO53597.1 - 0.067 13.5 0.7 2.6 8.5 0.0 4.0 5 0 0 5 5 5 0 HEAT repeat Cnd1 PF12717.7 EGO53597.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Kelch_4 PF13418.6 EGO53598.1 - 1.7e-37 127.1 5.3 9.3e-07 28.8 0.5 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EGO53598.1 - 6.2e-31 105.9 6.7 6.8e-09 35.5 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EGO53598.1 - 3.7e-30 103.3 4.3 7.5e-12 44.6 0.2 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 EGO53598.1 - 6.2e-29 99.3 3.7 6.8e-11 42.0 0.3 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGO53598.1 - 1.2e-27 95.6 10.0 7.5e-07 29.3 0.1 6.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EGO53598.1 - 4e-19 67.8 8.3 5.1e-08 32.6 0.2 6.6 6 1 0 6 6 6 4 Kelch motif Filament PF00038.21 EGO53598.1 - 0.0012 18.6 31.1 0.0012 18.6 31.1 4.3 2 1 2 4 4 4 1 Intermediate filament protein Cnn_1N PF07989.11 EGO53598.1 - 0.0098 16.0 2.0 0.0098 16.0 2.0 8.4 5 3 4 9 9 9 1 Centrosomin N-terminal motif 1 Mpv17_PMP22 PF04117.12 EGO53599.1 - 7.7e-13 48.5 5.6 7.7e-13 48.5 5.6 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family YIF1 PF03878.15 EGO53600.1 - 7.6e-97 323.5 2.0 8.8e-97 323.3 2.0 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EGO53600.1 - 0.00074 19.3 5.6 0.00074 19.3 5.6 1.6 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.13 EGO53601.1 - 4.1e-82 276.4 0.3 5.5e-82 276.0 0.3 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 EGO53601.1 - 4.4e-53 179.8 0.3 7.4e-53 179.1 0.3 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EGO53601.1 - 4.4e-09 36.4 0.2 1.3e-08 34.9 0.2 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EGO53601.1 - 9.4e-06 24.8 0.0 1.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EGO53601.1 - 0.00025 20.8 0.2 0.00051 19.8 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGO53601.1 - 0.0019 18.6 0.7 0.0046 17.4 0.1 1.9 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EGO53601.1 - 0.0075 16.3 0.5 2.1 8.4 0.1 2.8 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EGO53601.1 - 0.014 15.8 0.0 0.37 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 EGO53601.1 - 0.048 13.1 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGO53601.1 - 0.056 13.5 0.1 0.2 11.8 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EGO53601.1 - 0.071 13.6 0.0 0.2 12.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EGO53601.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain MPDZ_u10 PF16667.5 EGO53601.1 - 0.12 13.3 0.6 0.64 11.0 0.6 2.3 1 0 0 1 1 1 0 Unstructured region 10 on multiple PDZ protein AAA_33 PF13671.6 EGO53601.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EGO53601.1 - 0.19 11.4 0.2 0.46 10.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 EGO53601.1 - 0.22 11.6 0.9 1.9 8.6 0.4 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain PI3_PI4_kinase PF00454.27 EGO53602.1 - 6.6e-51 173.5 0.0 1.3e-50 172.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EGO53602.1 - 4.7e-40 137.9 0.4 9.2e-40 136.9 0.4 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.13 EGO53602.1 - 1.5e-29 101.9 0.1 5.4e-29 100.1 0.1 2.1 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 EGO53602.1 - 1.2e-17 63.4 0.0 6.1e-17 61.2 0.0 2.3 2 0 0 2 2 2 1 FATC domain TPR_7 PF13176.6 EGO53602.1 - 0.0047 16.9 1.1 4.3 7.6 0.0 3.6 3 0 0 3 3 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO53602.1 - 0.016 15.5 0.2 0.51 10.6 0.1 3.3 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGO53602.1 - 0.021 15.3 11.2 0.11 13.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGO53602.1 - 0.032 13.4 1.0 6.6 5.8 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGO53602.1 - 0.072 13.9 14.7 0.7 10.9 0.1 5.8 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGO53602.1 - 0.095 13.0 1.9 28 5.1 0.1 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4754 PF15946.5 EGO53602.1 - 0.15 12.3 0.0 0.54 10.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4754) TPR_16 PF13432.6 EGO53602.1 - 0.22 12.2 5.0 13 6.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGO53602.1 - 0.29 11.3 3.1 7 7.0 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO53602.1 - 0.73 10.6 4.4 2.3 9.0 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGO53602.1 - 3.8 7.9 10.7 3.2 8.1 0.2 4.9 4 2 2 6 6 6 0 Tetratricopeptide repeat zf-PARP PF00645.18 EGO53603.1 - 8e-24 84.3 0.6 5.3e-23 81.7 0.6 2.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Med17 PF10156.9 EGO53605.1 - 5.9e-101 338.5 0.0 7.6e-101 338.1 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.20 EGO53606.1 - 2.8e-184 610.9 0.3 1.3e-101 339.7 0.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.19 EGO53606.1 - 0.17 11.7 0.3 0.49 10.2 0.3 1.8 1 0 0 1 1 1 0 UvrB/uvrC motif SKG6 PF08693.10 EGO53607.1 - 3.3e-06 26.4 1.4 6.6e-06 25.4 1.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Fungal_lectin PF07938.12 EGO53607.1 - 0.0002 20.9 4.1 0.0019 17.6 0.3 2.6 2 1 1 3 3 3 2 Fungal fucose-specific lectin MGC-24 PF05283.11 EGO53607.1 - 0.08 13.4 1.0 0.19 12.2 1.0 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin OCRE PF17780.1 EGO53607.1 - 1.3 9.1 0.0 1.3 9.1 0.0 4.1 4 1 0 4 4 4 0 OCRE domain SNF2_N PF00176.23 EGO53608.1 - 5e-60 203.1 1.1 1.1e-59 202.0 0.7 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO53608.1 - 4.4e-15 56.0 0.0 1e-14 54.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 EGO53608.1 - 1.9e-08 34.0 2.2 4.1e-08 33.0 2.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO53608.1 - 1.1e-07 31.7 1.7 1.7e-07 31.1 0.7 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGO53608.1 - 1.6e-07 31.1 3.0 3.1e-07 30.1 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EGO53608.1 - 2.9e-07 30.6 0.0 6.1e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 EGO53608.1 - 6.4e-07 29.1 1.8 6.4e-07 29.1 1.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO53608.1 - 6.7e-07 29.5 3.3 1.5e-06 28.4 3.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGO53608.1 - 1.2e-06 28.3 2.2 2.5e-06 27.3 2.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGO53608.1 - 0.00037 20.6 4.8 0.001 19.2 4.9 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 EGO53608.1 - 0.0014 18.6 0.4 0.0036 17.2 0.4 1.7 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) TFIIA PF03153.13 EGO53608.1 - 0.0021 18.2 12.1 0.0045 17.0 12.1 1.7 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Prok-RING_4 PF14447.6 EGO53608.1 - 0.0058 16.5 9.0 0.18 11.7 9.3 2.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGO53608.1 - 0.014 15.2 3.4 0.076 12.8 3.7 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain AAA_14 PF13173.6 EGO53608.1 - 0.074 13.1 0.0 0.48 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain zf-RING_6 PF14835.6 EGO53608.1 - 0.7 9.8 2.8 1.8 8.5 0.9 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Phosphodiest PF01663.22 EGO53609.1 - 1.4e-94 317.7 0.6 2e-94 317.1 0.6 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGO53609.1 - 0.00034 20.1 0.1 0.0046 16.4 0.1 2.3 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.12 EGO53609.1 - 0.15 12.1 0.6 1.7 8.7 0.1 2.4 2 0 0 2 2 2 0 PglZ domain Sarcoglycan_1 PF04790.13 EGO53609.1 - 0.39 10.0 1.3 0.83 8.9 1.3 1.4 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Acetyltransf_9 PF13527.7 EGO53610.1 - 7.4e-07 29.3 0.1 1.3e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGO53610.1 - 1.8e-06 27.9 0.0 4.6e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO53610.1 - 0.00047 20.5 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO53610.1 - 0.00067 19.9 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.6 EGO53610.1 - 0.0086 16.0 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 EGO53610.1 - 0.023 14.1 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Ribosomal_L14e PF01929.17 EGO53611.1 - 1.1e-33 115.5 2.6 1.6e-33 115.0 2.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 NAC PF01849.18 EGO53612.1 - 1.2e-23 82.8 0.3 3.6e-23 81.3 0.1 2.0 2 0 0 2 2 2 1 NAC domain Mt_ATP-synt_D PF05873.12 EGO53612.1 - 2.1e-21 76.4 2.5 2.1e-21 76.4 2.5 1.8 1 1 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) LPP20 PF02169.16 EGO53612.1 - 2.5 8.5 5.6 0.73 10.2 1.1 2.5 2 1 0 2 2 2 0 LPP20 lipoprotein Myc_N PF01056.18 EGO53612.1 - 3 7.6 10.1 6 6.7 9.9 1.6 1 1 0 1 1 1 0 Myc amino-terminal region COX16 PF14138.6 EGO53617.1 - 6.4e-35 119.5 0.8 8.9e-35 119.1 0.3 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 Gal_mutarotas_2 PF13802.6 EGO53617.1 - 0.045 14.1 0.5 0.98 9.8 0.0 2.2 2 1 0 2 2 2 0 Galactose mutarotase-like Ribosomal_L41 PF05162.13 EGO53617.1 - 1.4 9.0 0.0 1.4 9.0 0.0 3.0 3 0 0 3 3 3 0 Ribosomal protein L41 Glyco_hydro_35 PF01301.19 EGO53618.1 - 2.7e-98 329.5 0.0 3.7e-98 329.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 EGO53618.1 - 7.2e-60 201.9 1.5 1.2e-59 201.2 1.5 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 EGO53618.1 - 3.6e-55 185.4 2.6 4.8e-31 107.7 0.1 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 EGO53618.1 - 1.1e-21 76.2 0.2 2.5e-21 75.0 0.2 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 ADH_N PF08240.12 EGO53619.1 - 1.1e-26 92.9 3.7 2.1e-26 91.9 3.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO53619.1 - 7.9e-16 58.2 0.0 1.2e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGO53619.1 - 4.7e-06 26.2 0.3 0.0013 18.3 0.2 2.4 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ATP-synt_G PF04718.15 EGO53620.1 - 2.2e-31 108.7 0.5 4.5e-31 107.6 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Methyltransf_23 PF13489.6 EGO53622.1 - 5e-16 59.0 0.0 7.4e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO53622.1 - 2.4e-07 31.4 0.0 5.7e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO53622.1 - 2.8e-05 24.7 0.0 9.1e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO53622.1 - 0.0013 19.4 0.0 0.0077 17.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO53622.1 - 0.0017 18.2 0.0 0.029 14.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO53622.1 - 0.0036 16.9 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EGO53622.1 - 0.079 12.3 0.0 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family AA_permease_2 PF13520.6 EGO53623.1 - 1.8e-47 162.2 42.4 2.2e-47 161.8 42.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO53623.1 - 5.8e-24 84.5 34.7 8.1e-24 84.0 34.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3623 PF12291.8 EGO53623.1 - 0.00086 18.6 1.4 0.00086 18.6 1.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3623) PufQ PF05398.11 EGO53623.1 - 0.081 13.1 0.0 0.36 11.0 0.0 2.1 1 0 0 1 1 1 0 PufQ cytochrome subunit NAPRTase PF04095.16 EGO53624.1 - 9.6e-57 192.3 0.3 1.3e-30 106.7 0.7 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EGO53624.1 - 8.1e-37 126.4 0.0 1.6e-36 125.5 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain WD40 PF00400.32 EGO53625.1 - 4.9e-08 33.5 15.7 0.1 13.5 0.0 8.2 10 0 0 10 10 10 2 WD domain, G-beta repeat PQQ_2 PF13360.6 EGO53625.1 - 5.8e-08 32.6 0.1 5.7e-07 29.4 0.0 2.6 1 1 1 2 2 2 1 PQQ-like domain ANAPC4_WD40 PF12894.7 EGO53625.1 - 2e-06 28.0 2.1 0.41 11.0 0.1 6.3 4 3 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO53625.1 - 0.00076 18.5 2.3 0.003 16.6 0.0 2.9 4 1 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 EGO53625.1 - 0.0014 18.4 0.0 0.14 12.1 0.0 2.8 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_3 PF13570.6 EGO53625.1 - 0.12 13.0 1.0 35 5.1 0.0 4.2 5 1 0 5 5 5 0 PQQ-like domain Cwf_Cwc_15 PF04889.12 EGO53625.1 - 1.2 8.8 15.2 0.39 10.4 4.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Rad4 PF03835.15 EGO53626.1 - 2.7e-13 49.8 0.8 6.2e-13 48.7 0.4 1.9 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EGO53626.1 - 2.8e-12 47.1 2.9 6.2e-12 46.0 2.9 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Pept_tRNA_hydro PF01195.19 EGO53627.1 - 0.14 12.2 0.0 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase Asp_protease_2 PF13650.6 EGO53628.1 - 4.4e-05 24.0 0.0 9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGO53628.1 - 0.018 15.6 0.0 0.038 14.5 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF5427 PF10310.9 EGO53629.1 - 1.9 7.4 6.5 2.4 7.0 6.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) MTBP_C PF14920.6 EGO53629.1 - 2.7 7.7 10.9 0.52 10.0 7.4 1.5 2 0 0 2 2 2 0 MDM2-binding PI3_PI4_kinase PF00454.27 EGO53630.1 - 4.4e-47 161.0 0.1 6.9e-32 111.2 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGO53630.1 - 5.9e-39 133.4 2.0 1.1e-26 93.4 0.3 2.3 1 1 1 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 EGO53630.1 - 2.5e-32 111.7 0.0 4.5e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.10 EGO53631.1 - 6.4e-32 109.7 0.0 1.7e-31 108.3 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EGO53631.1 - 1.5e-19 69.8 0.0 4.5e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE NOC3p PF07540.11 EGO53631.1 - 0.038 14.4 0.0 2 8.9 0.0 2.5 2 0 0 2 2 2 0 Nucleolar complex-associated protein DUF3298 PF11738.8 EGO53631.1 - 0.17 12.9 0.7 1.6 9.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) DUF4336 PF14234.6 EGO53632.1 - 4.6e-15 55.6 0.0 6.6e-10 38.7 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) DUF3719 PF12516.8 EGO53632.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) Amidase PF01425.21 EGO53633.1 - 3.2e-98 329.6 0.6 3.6e-97 326.2 0.6 2.5 1 1 0 1 1 1 1 Amidase Big_3_5 PF16640.5 EGO53633.1 - 0.085 13.0 3.0 0.22 11.7 2.9 1.8 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 3) PRP38 PF03371.15 EGO53635.1 - 6.8e-59 198.6 0.0 8.6e-59 198.3 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 EGO53635.1 - 0.00065 20.3 25.9 0.00065 20.3 25.9 1.7 2 0 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RSRP PF17069.5 EGO53635.1 - 0.0029 17.2 22.4 0.0042 16.7 22.4 1.2 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 PI3K_1B_p101 PF10486.9 EGO53635.1 - 0.031 12.1 0.4 0.036 11.9 0.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.14 EGO53635.1 - 0.62 8.3 6.1 0.8 7.9 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4778 PF16008.5 EGO53636.1 - 0.15 12.1 8.1 0.18 11.8 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) TFIIA PF03153.13 EGO53636.1 - 0.94 9.4 21.3 1.1 9.2 21.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NARP1 PF12569.8 EGO53636.1 - 1.6 7.5 12.5 2 7.2 12.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 YABBY PF04690.13 EGO53636.1 - 2.2 8.8 12.3 4.9 7.7 12.3 1.6 1 1 0 1 1 1 0 YABBY protein DUF4661 PF15576.6 EGO53636.1 - 4.4 7.1 7.6 5.3 6.9 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Lin-8 PF03353.15 EGO53636.1 - 9.7 5.6 18.0 13 5.3 18.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-P11 PF03854.14 EGO53637.1 - 0.0037 16.9 2.2 0.0055 16.4 2.2 1.2 1 0 0 1 1 1 1 P-11 zinc finger Metallophos PF00149.28 EGO53639.1 - 7e-10 39.7 5.0 9.1e-10 39.4 3.4 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase B12-binding PF02310.19 EGO53639.1 - 0.0063 16.5 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 B12 binding domain ATP-synt_C PF00137.21 EGO53641.1 - 1.8e-27 95.4 36.6 2.3e-17 63.0 13.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Birna_VP4 PF01768.16 EGO53641.1 - 0.71 9.6 2.9 0.76 9.5 2.2 1.3 1 1 0 1 1 1 0 Birnavirus VP4 protein CNH PF00780.22 EGO53642.1 - 2.4e-78 263.5 0.0 5.5e-78 262.3 0.0 1.6 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 EGO53642.1 - 4.6e-43 146.6 0.0 8.6e-43 145.7 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EGO53642.1 - 1.5e-34 119.8 0.0 2.5e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EGO53642.1 - 8e-16 57.9 0.1 1.4e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 EGO53642.1 - 0.0068 16.2 0.0 0.027 14.3 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain eIF2_C PF09173.11 EGO53643.1 - 3.8e-34 116.8 0.4 8.7e-34 115.6 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EGO53643.1 - 2.3e-22 79.5 1.5 3.3e-21 75.7 1.5 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGO53643.1 - 1.3e-10 41.5 0.2 2.8e-10 40.4 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGO53643.1 - 0.0037 17.3 0.0 0.0084 16.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EGO53643.1 - 0.0074 16.3 1.1 0.022 14.8 0.1 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 EGO53643.1 - 0.034 14.1 0.2 0.32 10.9 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase ProQ_C PF17516.2 EGO53643.1 - 0.16 11.4 1.0 0.37 10.2 1.0 1.6 1 0 0 1 1 1 0 ProQ C-terminal domain DUF2569 PF10754.9 EGO53644.1 - 0.76 10.2 6.7 0.37 11.2 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) ADK PF00406.22 EGO53645.1 - 1.7e-44 151.6 0.0 2e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGO53645.1 - 5.2e-35 120.8 0.0 7e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO53645.1 - 3.1e-07 31.0 0.0 4.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO53645.1 - 0.00012 22.3 0.0 0.00042 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGO53645.1 - 0.0005 19.8 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Ploopntkinase3 PF18751.1 EGO53645.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 PCI PF01399.27 EGO53646.1 - 9e-15 55.1 0.3 7.9e-14 52.0 0.1 2.5 3 1 0 3 3 3 1 PCI domain eIF3m_C_helix PF18005.1 EGO53646.1 - 3.3e-05 23.5 0.7 3.3e-05 23.5 0.7 2.2 3 0 0 3 3 3 1 eIF3 subunit M, C-terminal helix Nucleopor_Nup85 PF07575.13 EGO53646.1 - 0.018 13.6 0.2 0.026 13.1 0.2 1.2 1 0 0 1 1 1 0 Nup85 Nucleoporin Pkinase PF00069.25 EGO53647.1 - 1.1e-76 257.7 0.0 1.5e-76 257.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO53647.1 - 1.9e-37 128.9 0.0 2.5e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EGO53647.1 - 6.5e-16 58.4 0.2 1.9e-15 57.0 0.1 1.8 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.6 EGO53647.1 - 7.5e-11 41.9 0.0 4.4e-09 36.1 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Yop-YscD_cpl PF16697.5 EGO53647.1 - 3.5e-09 36.9 0.0 8.3e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 EGO53647.1 - 1.1e-06 27.7 0.0 1.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGO53647.1 - 0.0026 17.1 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EGO53647.1 - 0.069 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 EGO53647.1 - 0.072 12.7 0.3 6 6.4 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 EGO53647.1 - 0.094 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 EGO53647.1 - 0.21 11.5 1.3 0.63 9.9 0.1 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family HAMP PF00672.25 EGO53648.1 - 3.4e-40 136.2 17.4 7e-08 32.7 0.2 8.3 7 0 0 7 7 7 5 HAMP domain HATPase_c PF02518.26 EGO53648.1 - 1.2e-31 109.5 0.1 4.5e-31 107.7 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGO53648.1 - 2.1e-26 92.3 0.5 2.1e-26 92.3 0.5 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EGO53648.1 - 3.1e-17 62.4 4.1 7.7e-17 61.1 0.5 3.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 EGO53648.1 - 1.1e-08 35.3 11.1 3 8.3 0.0 7.1 3 2 3 7 7 7 3 Syntaxin-like protein DUF948 PF06103.11 EGO53648.1 - 4.2e-05 23.7 43.0 0.2 11.9 0.4 9.4 4 1 2 6 6 6 2 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 EGO53648.1 - 0.00045 20.4 31.2 0.15 12.2 1.7 6.5 6 0 0 6 6 6 2 Fibrinogen alpha/beta chain family DUF4279 PF14106.6 EGO53648.1 - 0.0021 18.3 0.0 15 5.8 0.0 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4279) DUF3829 PF12889.7 EGO53648.1 - 0.0062 16.1 11.4 0.73 9.3 0.2 4.5 4 1 0 4 4 4 2 Protein of unknown function (DUF3829) GLE1 PF07817.13 EGO53648.1 - 0.0088 15.3 9.4 3 7.0 0.2 4.1 3 1 2 5 5 5 3 GLE1-like protein DUF4795 PF16043.5 EGO53648.1 - 0.069 12.7 25.5 3 7.4 9.9 5.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4795) GhoS PF11080.8 EGO53648.1 - 0.34 10.9 5.6 0.83 9.7 0.1 3.7 4 0 0 4 4 4 0 Endoribonuclease GhoS CENP-F_leu_zip PF10473.9 EGO53648.1 - 0.62 10.1 26.4 5.7 7.0 0.1 8.1 7 3 0 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BORCS6 PF10157.9 EGO53648.1 - 0.68 10.2 10.5 22 5.2 0.1 5.2 4 2 0 5 5 5 0 BLOC-1-related complex sub-unit 6 DUF883 PF05957.13 EGO53648.1 - 1.9 9.2 18.2 6.3 7.5 0.1 6.1 6 1 1 7 7 7 0 Bacterial protein of unknown function (DUF883) DUF5593 PF18007.1 EGO53648.1 - 2.2 9.0 4.7 66 4.3 0.1 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5593) AAA_13 PF13166.6 EGO53648.1 - 4.7 5.7 24.4 0.22 10.1 1.3 3.4 1 1 1 3 3 3 0 AAA domain GRP PF07172.11 EGO53649.1 - 2.4 8.9 19.0 0.98 10.2 13.6 2.2 2 0 0 2 2 2 0 Glycine rich protein family HMG_box PF00505.19 EGO53651.1 - 2.4e-18 66.3 1.8 5.1e-18 65.2 1.8 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO53651.1 - 2e-13 50.7 1.7 2e-13 50.7 1.7 1.8 2 0 0 2 2 2 1 HMG-box domain SAM_1 PF00536.30 EGO53651.1 - 1.3e-08 35.1 0.0 2.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGO53651.1 - 4.4e-06 26.7 0.0 8.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD1 PF04904.13 EGO53651.1 - 0.0024 17.9 0.0 0.0065 16.4 0.0 1.6 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) WYL_3 PF18488.1 EGO53651.1 - 0.53 10.7 3.7 1.3 9.5 3.7 1.6 1 0 0 1 1 1 0 WYL domain Herpes_UL56 PF04534.12 EGO53655.1 - 0.012 15.2 4.0 0.016 14.7 4.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein Caskin-Pro-rich PF16907.5 EGO53655.1 - 0.015 15.8 0.7 0.036 14.6 0.7 1.7 1 0 0 1 1 1 0 Proline rich region of Caskin proteins PRIMA1 PF16101.5 EGO53655.1 - 0.072 13.1 2.3 0.11 12.5 2.3 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RCDG1 PF15725.5 EGO53655.1 - 0.45 11.0 6.9 0.2 12.1 3.9 1.9 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Na_Ca_ex PF01699.24 EGO53656.1 - 1.9e-48 164.2 38.4 3.5e-25 88.7 16.1 2.6 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Sigma_reg_N PF13800.6 EGO53656.1 - 8 6.8 5.2 49 4.3 0.4 3.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Cnd2 PF05786.14 EGO53657.1 - 5.8e-304 1010.7 16.0 1.3e-303 1009.6 16.0 1.5 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EGO53657.1 - 0.014 15.6 0.0 0.014 15.6 0.0 2.6 2 1 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Myc_N PF01056.18 EGO53657.1 - 0.17 11.8 7.5 2.2 8.1 0.2 2.5 2 0 0 2 2 2 0 Myc amino-terminal region Pep1_7 PF17232.2 EGO53657.1 - 3.2 8.3 5.8 3.8 8.0 0.8 2.9 2 0 0 2 2 2 0 Elicitor peptide 1-7 DUF5102 PF17104.5 EGO53658.1 - 8.1e-110 367.4 4.4 8.1e-110 367.4 4.4 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF5102) Nsp1_C PF05064.13 EGO53659.1 - 7.5e-43 145.0 5.0 1.7e-42 143.9 5.0 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EGO53659.1 - 6.4e-21 75.0 183.8 4.5e-07 30.6 42.3 6.9 1 1 5 6 6 6 5 Nucleoporin FG repeat region EzrA PF06160.12 EGO53659.1 - 0.067 11.4 8.3 0.15 10.2 0.1 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA MIP-T3_C PF17749.1 EGO53659.1 - 0.22 11.5 4.4 12 5.8 0.1 3.1 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region Mer2 PF09074.10 EGO53659.1 - 0.49 10.2 3.3 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Mer2 DUF948 PF06103.11 EGO53659.1 - 0.78 10.0 6.1 0.68 10.2 0.1 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PI_PP_I PF18363.1 EGO53659.1 - 0.8 9.9 2.5 1.8 8.8 2.5 1.5 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain Spc7 PF08317.11 EGO53659.1 - 0.84 8.5 6.2 0.36 9.7 2.0 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Med30 PF11315.8 EGO53659.1 - 1.1 9.4 2.7 7.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Mediator complex subunit 30 GAS PF13851.6 EGO53659.1 - 1.2 8.5 7.3 0.45 9.8 2.8 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Prominin PF05478.11 EGO53659.1 - 1.8 6.4 4.7 1.4 6.8 1.5 1.9 2 0 0 2 2 2 0 Prominin DUF4200 PF13863.6 EGO53659.1 - 2 8.8 11.2 38 4.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spc24 PF08286.11 EGO53659.1 - 2.3 8.5 5.5 1.7 8.9 1.3 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 HIP1_clath_bdg PF16515.5 EGO53659.1 - 3.5 8.3 5.7 50 4.6 2.8 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Syntaxin-6_N PF09177.11 EGO53659.1 - 4.6 7.9 5.8 21 5.7 3.2 2.7 2 2 0 2 2 2 0 Syntaxin 6, N-terminal MscS_porin PF12795.7 EGO53659.1 - 5.1 6.6 10.9 1 8.8 5.6 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain OmpH PF03938.14 EGO53659.1 - 5.6 7.3 15.1 3.6 7.9 0.1 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) IATP PF04568.12 EGO53660.1 - 2.5e-29 101.6 1.0 2.9e-29 101.4 1.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF489 PF04356.12 EGO53660.1 - 0.073 13.1 0.4 0.091 12.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF2205 PF10224.9 EGO53660.1 - 0.15 12.0 3.8 0.22 11.6 3.8 1.2 1 0 0 1 1 1 0 Short coiled-coil protein 14-3-3 PF00244.20 EGO53661.1 - 5.9e-107 356.2 3.9 6.8e-107 356.0 3.9 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 EGO53661.1 - 0.051 14.1 2.5 0.73 10.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-CSL PF05207.13 EGO53662.1 - 3.9e-18 64.9 0.7 6.2e-18 64.3 0.7 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 EGO53662.1 - 1.6e-13 50.5 0.1 8.1e-08 32.3 0.0 2.4 1 1 1 2 2 2 2 DnaJ domain DUF3797 PF12677.7 EGO53662.1 - 0.093 12.6 1.0 0.6 10.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) SR-25 PF10500.9 EGO53662.1 - 0.71 9.4 8.0 1.1 8.9 8.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mitoc_mL59 PF18126.1 EGO53663.1 - 2.1e-47 160.6 4.2 2.5e-47 160.4 4.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 DEAD PF00270.29 EGO53664.1 - 6.3e-48 162.9 0.0 5.5e-47 159.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO53664.1 - 3.8e-29 101.3 0.0 2.5e-28 98.6 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO53664.1 - 0.0013 18.8 0.0 0.0039 17.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PRAI PF00697.22 EGO53664.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF3334 PF11813.8 EGO53664.1 - 0.23 11.2 0.2 1 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3334) Mito_carr PF00153.27 EGO53665.1 - 7.7e-61 202.1 0.0 6.9e-21 74.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TspO_MBR PF03073.15 EGO53666.1 - 1.8e-43 147.8 6.7 2.4e-43 147.4 6.7 1.1 1 0 0 1 1 1 1 TspO/MBR family DUF3546 PF12066.8 EGO53667.1 - 2.7e-35 120.9 3.1 2.7e-35 120.9 3.1 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 EGO53667.1 - 3.1e-13 50.6 0.1 1e-12 48.9 0.1 2.0 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 EGO53667.1 - 5e-12 45.4 0.1 1.2e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) FolB PF02152.18 EGO53668.1 - 6e-24 84.7 0.1 2.3e-19 70.0 0.1 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase UDPGP PF01704.18 EGO53669.1 - 6.1e-191 634.5 0.1 7.2e-191 634.3 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ING PF12998.7 EGO53670.1 - 7.2e-22 77.9 6.7 1.3e-21 77.1 6.7 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EGO53670.1 - 0.00013 21.7 8.6 0.00023 21.0 8.6 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EGO53670.1 - 0.17 12.1 1.1 0.42 10.9 0.9 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain DUF2552 PF10827.8 EGO53670.1 - 0.18 12.0 0.7 1.4 9.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) DUF2408 PF10303.9 EGO53670.1 - 0.2 12.2 2.7 0.34 11.5 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) zf-RING_2 PF13639.6 EGO53670.1 - 0.42 11.0 5.8 0.74 10.2 5.8 1.4 1 0 0 1 1 1 0 Ring finger domain MIP-T3_C PF17749.1 EGO53670.1 - 1.3 9.0 5.8 0.34 10.9 2.2 1.9 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Hist_deacetyl PF00850.19 EGO53671.1 - 1.5e-78 264.4 0.0 2.1e-78 263.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain WW PF00397.26 EGO53673.1 - 1.3e-11 44.4 0.1 4.4e-11 42.7 0.1 2.0 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 EGO53673.1 - 0.00067 18.8 0.1 0.036 13.1 0.1 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase MFS_1 PF07690.16 EGO53674.1 - 6.3e-16 58.2 10.5 6.3e-16 58.2 10.5 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily MPS2 PF17060.5 EGO53676.1 - 0.015 14.6 7.0 0.052 12.8 7.0 1.9 1 0 0 1 1 1 0 Monopolar spindle protein 2 Mod_r PF07200.13 EGO53676.1 - 6 7.0 22.3 2.9 8.0 11.8 3.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Glyco_hydro_47 PF01532.20 EGO53677.1 - 7.2e-173 575.7 0.0 1.1e-172 575.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 YtxH PF12732.7 EGO53677.1 - 0.34 11.5 4.3 0.98 10.0 4.3 1.8 1 0 0 1 1 1 0 YtxH-like protein Borrelia_P83 PF05262.11 EGO53677.1 - 1.6 7.1 6.7 2.4 6.6 6.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein MT0933_antitox PF14013.6 EGO53677.1 - 2.3 8.6 6.3 2.7 8.4 3.2 2.5 2 1 0 2 2 2 0 MT0933-like antitoxin protein Glyco_hydro_9 PF00759.19 EGO53677.1 - 3 7.2 9.8 2.9 7.2 8.4 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 Autophagy_act_C PF03987.15 EGO53678.1 - 0.00052 20.5 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_1 PF00076.22 EGO53679.1 - 3.7e-09 36.3 0.0 1.1e-08 34.8 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGO53679.1 - 2.9e-05 23.6 0.0 4.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO53679.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EGO53679.1 - 0.052 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 DUF1180 PF06679.12 EGO53679.1 - 2.7 8.4 7.9 48 4.3 5.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) WD40 PF00400.32 EGO53680.1 - 5.1e-16 58.8 9.3 0.0023 18.7 0.2 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO53680.1 - 2e-06 28.0 0.0 0.034 14.5 0.0 3.9 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGO53680.1 - 0.0027 17.6 0.0 1.7 8.7 0.0 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Collagen PF01391.18 EGO53681.1 - 0.0004 20.1 13.6 0.00087 19.0 13.6 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) AA_permease PF00324.21 EGO53682.1 - 3.5e-136 454.6 39.8 4.5e-136 454.2 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO53682.1 - 1.1e-35 123.3 42.4 1.5e-35 122.9 42.4 1.2 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 EGO53682.1 - 0.0053 15.6 0.3 0.0053 15.6 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4781) MFS_1 PF07690.16 EGO53683.1 - 1.9e-20 73.1 19.2 1.9e-20 73.1 19.2 2.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO53683.1 - 0.015 14.2 7.0 0.033 13.1 7.0 1.5 1 0 0 1 1 1 0 Sugar (and other) transporter UBA_4 PF14555.6 EGO53684.1 - 0.0028 17.4 0.0 0.006 16.4 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Mcm10 PF09332.11 EGO53684.1 - 0.037 13.5 1.6 0.044 13.2 1.6 1.0 1 0 0 1 1 1 0 Mcm10 replication factor DAHP_synth_2 PF01474.16 EGO53685.1 - 5.6e-202 671.0 0.0 6.3e-202 670.8 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family CCDC24 PF15669.5 EGO53685.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Aldose_epim PF01263.20 EGO53686.1 - 7.5e-37 127.3 0.0 5.8e-20 71.8 0.0 2.0 2 0 0 2 2 2 2 Aldose 1-epimerase Fungal_trans PF04082.18 EGO53687.1 - 2.5e-10 39.8 2.5 1.3e-09 37.5 0.1 2.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO53687.1 - 9.2e-07 28.9 10.4 2e-06 27.8 10.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EGO53687.1 - 5.5e-05 23.4 2.0 0.16 12.5 0.2 3.4 1 1 1 2 2 2 2 Zinc finger, C2H2 type Ric8 PF10165.9 EGO53688.1 - 8.1e-133 443.8 0.0 9.6e-133 443.6 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.8 EGO53689.1 - 1.1e-134 449.2 2.8 1.5e-134 448.7 2.8 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal MBOAT_2 PF13813.6 EGO53690.1 - 7.1e-14 51.8 6.0 7.7e-14 51.7 0.2 3.3 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Telomerase_RBD PF12009.8 EGO53691.1 - 2e-50 170.4 1.0 3.4e-50 169.6 0.2 1.9 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 EGO53691.1 - 7.6e-14 51.7 0.0 1.6e-10 40.9 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) TERT_thumb PF17984.1 EGO53691.1 - 0.022 14.6 0.3 0.051 13.5 0.3 1.5 1 0 0 1 1 1 0 Telomerase reverse transcriptase thumb DNA binding domain RhoGEF PF00621.20 EGO53692.1 - 8.7e-29 101.0 0.3 3e-28 99.3 0.0 2.0 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.18 EGO53692.1 - 2e-12 47.3 0.5 5.5e-12 45.9 0.5 1.7 1 0 0 1 1 1 1 BAR domain SUIM_assoc PF16619.5 EGO53692.1 - 0.0036 17.3 12.1 0.42 10.7 6.0 4.0 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 MOSC PF03473.17 EGO53693.1 - 5.2e-10 39.4 0.3 5.9e-10 39.3 0.3 1.0 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 EGO53694.1 - 2e-28 99.4 0.0 2.6e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 EGO53694.1 - 4e-20 71.9 0.0 7.5e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain AAA_16 PF13191.6 EGO53695.1 - 1e-14 55.3 0.0 3.8e-14 53.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGO53695.1 - 4.9e-14 52.8 0.0 1.1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EGO53695.1 - 1.9e-08 34.8 0.0 4.3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 EGO53695.1 - 4.2e-07 29.8 0.1 1.8e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain TniB PF05621.11 EGO53695.1 - 1.3e-06 27.9 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_lid_10 PF17872.1 EGO53695.1 - 5.9e-06 26.3 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain NACHT PF05729.12 EGO53695.1 - 9.2e-06 25.7 0.0 2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 EGO53695.1 - 0.00015 22.1 0.3 0.00039 20.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 EGO53695.1 - 0.00028 20.2 0.0 0.00048 19.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 EGO53695.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region KAP_NTPase PF07693.14 EGO53695.1 - 0.0016 17.8 0.1 0.0038 16.5 0.1 1.8 1 1 0 1 1 1 1 KAP family P-loop domain AAA_30 PF13604.6 EGO53695.1 - 0.0035 17.1 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EGO53695.1 - 0.005 16.1 0.0 0.0073 15.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EGO53695.1 - 0.0058 16.6 0.1 0.015 15.2 0.1 1.7 1 1 0 1 1 1 1 NTPase AAA_14 PF13173.6 EGO53695.1 - 0.013 15.6 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RFX_DNA_binding PF02257.15 EGO53695.1 - 0.014 16.0 0.0 0.78 10.4 0.0 2.4 2 0 0 2 2 2 0 RFX DNA-binding domain ATPase_2 PF01637.18 EGO53695.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 EGO53695.1 - 0.022 13.9 0.0 0.073 12.2 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EGO53695.1 - 0.024 15.0 0.0 0.046 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 EGO53695.1 - 0.037 14.0 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EGO53695.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 EGO53695.1 - 0.15 12.7 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGO53695.1 - 0.54 10.0 1.5 0.87 9.4 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Velvet PF11754.8 EGO53696.1 - 3.8e-63 213.7 0.0 3.8e-63 213.7 0.0 2.5 1 1 1 2 2 2 1 Velvet factor Presenilin PF01080.17 EGO53696.1 - 1.4 7.6 2.7 1.8 7.2 2.7 1.2 1 0 0 1 1 1 0 Presenilin DUF3602 PF12223.8 EGO53697.1 - 4.6e-15 56.0 8.2 1.1e-12 48.3 2.6 3.9 3 2 1 4 4 4 2 Protein of unknown function (DUF3602) SelP_N PF04592.14 EGO53697.1 - 0.38 10.1 12.0 0.58 9.5 12.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Neur_chan_memb PF02932.16 EGO53697.1 - 4.5 7.3 4.8 5.1 7.1 4.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 EGO53697.1 - 6.5 5.4 8.2 7.9 5.1 8.2 1.2 1 0 0 1 1 1 0 Presenilin PRTP PF01366.18 EGO53697.1 - 7.7 4.4 9.2 7.3 4.5 8.7 1.3 1 1 0 1 1 1 0 Herpesvirus processing and transport protein URO-D PF01208.17 EGO53698.1 - 6.1e-131 436.7 0.0 6.8e-131 436.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Pex26 PF07163.12 EGO53698.1 - 0.073 12.4 0.2 0.12 11.6 0.2 1.3 1 0 0 1 1 1 0 Pex26 protein HTH_19 PF12844.7 EGO53699.1 - 0.069 13.2 0.0 0.49 10.4 0.0 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain Zn_clus PF00172.18 EGO53701.1 - 1.7e-06 28.0 13.7 3.1e-06 27.2 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 EGO53704.1 - 4.3e-08 33.6 0.2 6.4e-08 33.1 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 EGO53705.1 - 1.3e-11 44.7 0.0 2.5e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGO53705.1 - 4.1e-10 40.3 0.1 9.8e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGO53705.1 - 0.0012 19.1 0.0 0.0028 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGO53705.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EGO53705.1 - 0.011 16.1 0.0 0.056 13.9 0.1 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGO53705.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 EGO53705.1 - 0.021 15.2 0.0 0.067 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EGO53705.1 - 0.027 14.3 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 EGO53705.1 - 0.05 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.14 EGO53705.1 - 0.064 12.5 1.0 0.14 11.4 0.5 1.7 1 1 1 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.6 EGO53705.1 - 0.085 13.4 0.2 0.56 10.7 0.2 2.4 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGO53705.1 - 0.12 12.3 0.0 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 NTPase PIF1 PF05970.14 EGO53705.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase CbiA PF01656.23 EGO53705.1 - 0.21 11.7 0.8 0.74 9.9 0.0 2.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PNP_UDP_1 PF01048.20 EGO53706.1 - 0.011 15.1 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 0 Phosphorylase superfamily K_channel_TID PF07941.11 EGO53707.1 - 1.4 9.4 16.4 2.5 8.6 4.3 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Dynamin_N PF00350.23 EGO53710.1 - 0.03 14.4 6.2 0.47 10.5 7.8 2.2 2 0 0 2 2 2 0 Dynamin family GREB1 PF15782.5 EGO53710.1 - 0.041 11.0 20.6 0.055 10.6 20.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 EGO53710.1 - 0.041 12.0 13.4 0.053 11.6 13.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.12 EGO53710.1 - 0.067 13.5 13.5 0.15 12.4 13.5 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family DUF572 PF04502.13 EGO53710.1 - 0.08 12.6 17.1 0.16 11.6 17.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) eIF-3_zeta PF05091.12 EGO53710.1 - 0.11 11.5 20.5 0.17 10.8 20.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF778 PF05608.12 EGO53710.1 - 0.56 10.5 6.2 1.3 9.4 6.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF778) DUF4569 PF15133.6 EGO53710.1 - 0.66 9.7 21.1 1.5 8.4 21.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) AIF_C PF14721.6 EGO53710.1 - 0.84 10.0 12.1 1.3 9.4 9.4 2.5 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Zip PF02535.22 EGO53710.1 - 3.1 6.9 13.1 6.6 5.8 13.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4407 PF14362.6 EGO53710.1 - 3.3 7.0 20.6 7 5.9 20.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C2H2_3rep PF18868.1 EGO53710.1 - 6.4 7.5 15.2 0.77 10.4 0.2 3.0 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Ctr PF04145.15 EGO53710.1 - 7 7.3 8.9 21 5.7 8.9 1.9 1 0 0 1 1 1 0 Ctr copper transporter family VCBS PF13517.6 EGO53712.1 - 8.1e-13 48.8 7.6 3.1e-06 27.7 1.1 2.7 2 1 1 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_C PF14782.6 EGO53712.1 - 0.32 9.7 0.0 0.48 9.1 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal MFS_1 PF07690.16 EGO53713.1 - 3.6e-11 42.6 2.8 4.3e-11 42.3 2.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily O_anti_polymase PF01901.16 EGO53713.1 - 0.0071 15.7 0.1 0.0075 15.6 0.1 1.1 1 0 0 1 1 1 1 Putative O-antigen polymerase DUF423 PF04241.15 EGO53713.1 - 0.05 13.8 0.1 0.26 11.5 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF423) MAPEG PF01124.18 EGO53714.1 - 5.7e-26 90.9 0.6 6.8e-26 90.7 0.6 1.1 1 0 0 1 1 1 1 MAPEG family Kelch_5 PF13854.6 EGO53715.1 - 2.1e-07 30.8 8.2 4.3e-06 26.6 0.1 3.8 4 0 0 4 4 4 2 Kelch motif RskA PF10099.9 EGO53715.1 - 6.5e-05 23.3 0.4 0.00011 22.5 0.4 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Kelch_2 PF07646.15 EGO53715.1 - 0.00012 21.8 2.3 0.53 10.4 0.1 3.9 3 0 0 3 3 3 1 Kelch motif SKG6 PF08693.10 EGO53715.1 - 0.00079 18.8 0.3 0.0014 18.0 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_6 PF13964.6 EGO53715.1 - 0.0048 17.1 1.4 0.12 12.7 0.2 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 EGO53715.1 - 0.0068 16.0 5.9 0.34 10.5 0.1 4.0 4 0 0 4 4 4 1 Kelch motif TMEM51 PF15345.6 EGO53715.1 - 0.013 15.4 2.4 0.023 14.6 2.4 1.4 1 1 0 1 1 1 0 Transmembrane protein 51 Ribosomal_L5e PF17144.4 EGO53715.1 - 0.043 13.8 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal large subunit proteins 60S L5, and 50S L18 DUF5316 PF17247.2 EGO53715.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5316) Spt20 PF12090.8 EGO53715.1 - 2.7 7.6 10.1 4.3 6.9 10.1 1.3 1 0 0 1 1 1 0 Spt20 family HET PF06985.11 EGO53716.1 - 5.5e-22 78.7 0.0 9.5e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UFD1 PF03152.14 EGO53716.1 - 0.005 16.3 0.0 0.0077 15.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Glyco_hydro_71 PF03659.14 EGO53718.1 - 2.8e-123 411.4 7.6 4e-123 410.9 7.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 P3A PF08727.11 EGO53718.1 - 0.076 12.4 0.4 7.8 6.0 0.0 2.7 2 0 0 2 2 2 0 Poliovirus 3A protein like Pullulanase_Ins PF18494.1 EGO53718.1 - 0.077 13.5 0.5 0.9 10.1 0.3 2.5 2 0 0 2 2 2 0 Pullulanase Ins domain MOSC PF03473.17 EGO53722.1 - 3.2e-20 72.5 0.0 7.5e-20 71.3 0.0 1.7 1 1 0 1 1 1 1 MOSC domain MPP6 PF10175.9 EGO53722.1 - 1.1 9.8 6.4 0.16 12.5 0.6 2.4 3 0 0 3 3 3 0 M-phase phosphoprotein 6 TPR_10 PF13374.6 EGO53723.1 - 6.1e-42 140.4 0.1 3.1e-11 42.7 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGO53723.1 - 4.5e-33 113.4 1.2 2.7e-13 50.0 0.0 4.5 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGO53723.1 - 3.2e-08 33.0 3.0 0.0057 16.6 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat NB-ARC PF00931.22 EGO53723.1 - 5e-08 32.4 0.0 1.4e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain TPR_4 PF07721.14 EGO53723.1 - 3.7e-07 30.1 0.4 0.91 10.3 0.3 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGO53723.1 - 5.7e-07 30.1 10.7 0.033 14.8 0.2 5.0 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGO53723.1 - 8e-06 25.6 1.4 0.95 9.7 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGO53723.1 - 1e-05 25.1 0.4 2.1e-05 24.1 0.4 1.5 1 0 0 1 1 1 1 MalT-like TPR region TPR_1 PF00515.28 EGO53723.1 - 2.1e-05 24.1 0.1 0.41 10.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGO53723.1 - 3.3e-05 24.3 0.9 32 5.7 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat NACHT PF05729.12 EGO53723.1 - 0.0001 22.3 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_19 PF14559.6 EGO53723.1 - 0.00021 21.8 2.1 0.3 11.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGO53723.1 - 0.016 15.3 0.2 25 5.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_25 PF13481.6 EGO53723.1 - 0.027 14.1 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPR_17 PF13431.6 EGO53723.1 - 0.1 13.0 0.4 1.1 9.8 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat AAA_22 PF13401.6 EGO53723.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ANAPC3 PF12895.7 EGO53723.1 - 0.12 12.6 0.1 2.9 8.2 0.0 3.3 2 2 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGO53723.1 - 0.21 12.3 0.8 1.7e+02 3.2 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat NACHT_sigma PF17106.5 EGO53723.1 - 0.99 9.6 10.5 1.8 8.8 10.5 1.4 1 0 0 1 1 1 0 Sigma domain on NACHT-NTPases SBDS PF01172.18 EGO53727.1 - 1.3e-24 86.1 0.3 1.5e-24 85.9 0.3 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.20 EGO53728.1 - 1.6e-19 70.8 0.0 4.5e-19 69.4 0.0 1.8 1 1 0 1 1 1 1 RhoGEF domain Nas2_N PF18265.1 EGO53730.1 - 2.4e-30 104.3 0.1 3.4e-30 103.8 0.1 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EGO53730.1 - 3.2e-09 36.5 0.1 6.3e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EGO53730.1 - 4.2e-07 30.2 0.0 7.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EGO53730.1 - 6.5e-06 26.5 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 EGO53730.1 - 1.9e-05 25.0 0.1 2.9e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Ras PF00071.22 EGO53731.1 - 3e-49 166.7 0.0 3.6e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO53731.1 - 4.5e-30 104.3 0.1 1.1e-29 103.0 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO53731.1 - 2e-10 40.4 0.0 2.6e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGO53731.1 - 0.00024 21.2 0.0 0.00044 20.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGO53731.1 - 0.0008 19.8 0.1 0.0048 17.3 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 EGO53731.1 - 0.0023 17.3 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGO53731.1 - 0.015 14.5 1.7 1.4 8.0 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.12 EGO53731.1 - 0.017 14.6 0.1 0.033 13.6 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 EGO53731.1 - 0.02 14.4 0.1 0.032 13.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EGO53731.1 - 0.038 13.9 0.1 8.9 6.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EGO53731.1 - 0.057 13.1 0.3 0.076 12.7 0.3 1.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGO53731.1 - 0.09 12.9 0.2 0.2 11.8 0.2 1.6 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EGO53731.1 - 0.094 12.1 0.0 0.16 11.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 EGO53731.1 - 0.11 12.4 0.2 0.24 11.4 0.2 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EGO53731.1 - 0.12 12.7 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EGO53731.1 - 0.12 11.6 0.4 0.26 10.5 0.1 1.7 2 0 0 2 2 2 0 Septin STAS PF01740.21 EGO53731.1 - 0.17 11.5 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 STAS domain ATPase PF06745.13 EGO53731.1 - 0.2 11.0 0.2 0.31 10.3 0.2 1.2 1 0 0 1 1 1 0 KaiC WSC PF01822.19 EGO53732.1 - 2.3e-90 296.9 90.6 1.8e-19 69.7 7.7 5.3 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.11 EGO53732.1 - 1.2e-27 96.7 0.0 2.3e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EGO53732.1 - 2.2e-20 72.7 0.0 5e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 EGO53732.1 - 0.074 13.4 0.1 0.62 10.4 0.0 2.6 3 0 0 3 3 3 0 Kelch motif Aldedh PF00171.22 EGO53733.1 - 3.8e-135 451.0 0.3 4.6e-135 450.7 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4880 PF16220.5 EGO53733.1 - 0.07 13.0 0.3 0.18 11.8 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) Calreticulin PF00262.18 EGO53734.1 - 2.7e-168 559.6 15.8 3.9e-168 559.0 15.8 1.2 1 0 0 1 1 1 1 Calreticulin family Aldolase_II PF00596.21 EGO53735.1 - 3.2e-43 147.8 0.0 3.8e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain LcnG-beta PF11632.8 EGO53735.1 - 2.6 8.1 6.3 0.88 9.6 2.9 2.0 2 0 0 2 2 2 0 Lactococcin G-beta PA PF02225.22 EGO53736.1 - 0.35 10.9 6.0 0.33 11.0 0.6 2.5 1 1 0 2 2 2 0 PA domain TIL PF01826.17 EGO53736.1 - 0.92 9.8 11.4 0.16 12.2 1.6 2.3 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain adh_short PF00106.25 EGO53737.1 - 1.4e-25 90.0 0.1 1.4e-21 76.9 0.0 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO53737.1 - 7e-19 68.3 0.0 8.9e-14 51.6 0.0 3.0 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO53737.1 - 5.4e-09 36.2 0.0 7.1e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO53737.1 - 0.016 14.7 0.1 0.025 14.0 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EGO53737.1 - 0.039 13.3 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) SLD5_C PF16922.5 EGO53738.1 - 5.1e-13 49.0 0.1 8.3e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EGO53738.1 - 1.1e-07 32.2 0.2 2.8e-07 31.0 0.2 1.6 1 0 0 1 1 1 1 GINS complex protein SnoaL PF07366.12 EGO53740.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Pkinase PF00069.25 EGO53741.1 - 3.4e-66 223.3 0.0 4.6e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO53741.1 - 2.3e-40 138.5 0.0 3.3e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EGO53741.1 - 7.7e-08 32.4 0.5 4.1e-05 23.7 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EGO53741.1 - 7.2e-07 28.8 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGO53741.1 - 0.0015 17.9 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGO53741.1 - 0.065 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EGO53741.1 - 0.069 11.9 0.1 0.069 11.9 0.1 2.3 3 0 0 3 3 3 0 Fungal protein kinase Sushi_2 PF09014.10 EGO53741.1 - 0.083 12.8 0.2 0.2 11.5 0.2 1.6 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain OPA3 PF07047.12 EGO53742.1 - 2.5e-44 150.1 0.9 2.5e-44 150.1 0.9 1.3 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) GvpG PF05120.12 EGO53742.1 - 0.034 14.2 2.3 0.044 13.8 0.4 2.0 2 0 0 2 2 2 0 Gas vesicle protein G Ca_chan_IQ PF08763.11 EGO53742.1 - 0.11 12.7 0.2 0.54 10.5 0.0 2.2 2 1 0 2 2 2 0 Voltage gated calcium channel IQ domain CCDC53 PF10152.9 EGO53743.1 - 0.51 10.8 4.5 0.58 10.6 4.5 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Complex1_LYR_2 PF13233.6 EGO53744.1 - 2.6e-19 69.7 0.1 3.5e-19 69.3 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EGO53744.1 - 7.1e-10 38.8 0.3 1.3e-09 37.9 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 EGO53744.1 - 0.0052 17.4 0.1 0.0085 16.7 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like HA2 PF04408.23 EGO53745.1 - 2.9e-18 66.1 0.0 6.7e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGO53745.1 - 5.9e-13 49.1 0.0 1.9e-12 47.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EGO53745.1 - 7.1e-10 39.1 0.1 2.8e-09 37.2 0.1 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EGO53745.1 - 4.1e-08 33.2 0.1 1e-07 31.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGO53745.1 - 1.2e-05 25.6 0.0 2.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGO53745.1 - 0.017 15.6 0.0 0.044 14.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EGO53745.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EGO53745.1 - 0.086 12.6 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGO53745.1 - 0.12 12.8 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain TRP PF06011.12 EGO53746.1 - 1.2e-142 475.7 20.6 1.5e-142 475.3 20.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EGO53746.1 - 5.9e-40 136.9 3.3 1.1e-39 135.9 3.3 1.5 1 0 0 1 1 1 1 ML-like domain DUF2207 PF09972.9 EGO53746.1 - 0.14 10.9 9.0 0.65 8.7 9.0 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) HemY_N PF07219.13 EGO53746.1 - 6.1 7.1 11.8 67 3.8 0.0 3.4 2 1 1 3 3 3 0 HemY protein N-terminus zf-C2H2 PF00096.26 EGO53747.1 - 0.035 14.6 23.1 0.2 12.2 0.4 5.3 5 0 0 5 5 5 0 Zinc finger, C2H2 type Tmemb_14 PF03647.13 EGO53748.1 - 4.5e-23 81.8 1.7 4.9e-23 81.7 1.7 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Cmc1 PF08583.10 EGO53749.1 - 3e-18 65.6 3.8 3.7e-18 65.3 3.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 EGO53749.1 - 0.026 14.8 0.5 2 8.8 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EGO53749.1 - 0.028 14.4 1.2 0.066 13.2 1.1 1.7 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 EGO53749.1 - 0.24 11.8 2.5 10 6.6 0.3 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Prefoldin_2 PF01920.20 EGO53750.1 - 4e-27 94.2 7.1 4.5e-27 94.1 7.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF2205 PF10224.9 EGO53750.1 - 0.0024 17.8 5.6 0.077 13.0 0.3 2.1 2 0 0 2 2 2 2 Short coiled-coil protein DUF2089 PF09862.9 EGO53750.1 - 0.0066 16.5 0.8 0.044 13.8 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2089) DUF4757 PF15949.5 EGO53750.1 - 0.011 16.2 0.3 0.014 15.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) Prefoldin PF02996.17 EGO53750.1 - 0.014 15.3 4.7 0.11 12.4 0.4 2.2 1 1 1 2 2 2 0 Prefoldin subunit THOC7 PF05615.13 EGO53750.1 - 0.017 15.4 2.1 1.4 9.2 2.1 2.1 1 1 0 1 1 1 0 Tho complex subunit 7 Cep57_MT_bd PF06657.13 EGO53750.1 - 0.3 11.6 3.8 0.33 11.4 0.1 2.2 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 CBFD_NFYB_HMF PF00808.23 EGO53752.1 - 1.1e-29 102.5 1.1 1.5e-29 102.1 1.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGO53752.1 - 8.5e-07 29.4 0.3 2e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 EGO53752.1 - 0.00089 19.2 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EGO53752.1 - 0.0012 18.8 0.1 0.0025 17.8 0.1 1.5 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 EGO53752.1 - 0.0018 18.3 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 EGO53752.1 - 0.044 14.3 0.0 0.078 13.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DUF4770 PF15994.5 EGO53752.1 - 0.048 13.9 0.6 1.2 9.3 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4770) baeRF_family12 PF18856.1 EGO53752.1 - 0.11 13.0 1.2 2.1 8.9 0.1 2.4 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 RRN3 PF05327.11 EGO53753.1 - 2.7e-155 518.1 1.1 2.7e-155 518.1 1.1 2.0 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 bZIP_1 PF00170.21 EGO53754.1 - 3.5e-07 30.2 1.2 6.7e-07 29.3 1.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EGO53754.1 - 0.0011 19.5 2.3 0.0022 18.5 2.3 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF4686 PF15742.5 EGO53754.1 - 0.036 13.2 0.3 0.053 12.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) CCDC-167 PF15188.6 EGO53754.1 - 0.095 13.1 1.1 0.15 12.4 1.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF812 PF05667.11 EGO53754.1 - 0.44 9.4 7.6 0.65 8.8 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ASD2 PF08687.11 EGO53754.1 - 10 5.6 14.3 0.11 12.0 1.6 2.1 1 1 1 2 2 2 0 Apx/Shroom domain ASD2 Patatin PF01734.22 EGO53756.1 - 2.6e-06 27.8 0.0 5.6e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.22 EGO53757.1 - 9.6e-21 74.9 0.0 2.4e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.22 EGO53757.1 - 6.7e-09 35.3 0.0 1.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.6 EGO53757.1 - 6.2e-06 26.4 6.6 0.046 14.0 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TniB PF05621.11 EGO53757.1 - 0.00022 20.7 0.0 0.00084 18.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial TniB protein AAA_5 PF07728.14 EGO53757.1 - 0.039 14.0 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO53757.1 - 0.046 14.1 0.0 0.18 12.2 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 EGO53757.1 - 0.065 12.6 0.0 10 5.4 0.0 2.7 2 0 0 2 2 2 0 KaiC TPR_14 PF13428.6 EGO53757.1 - 0.2 12.5 4.5 52 5.0 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGO53757.1 - 0.21 11.5 1.1 3.3 7.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Tubulin PF00091.25 EGO53758.1 - 1.9 8.6 4.2 5.7 7.1 0.2 2.3 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain GTP_EFTU PF00009.27 EGO53760.1 - 1.2e-05 24.9 0.0 2.8e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 EGO53760.1 - 0.06 13.1 1.2 0.25 11.1 0.3 2.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain T2SSE PF00437.20 EGO53760.1 - 0.065 12.3 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 EGO53760.1 - 0.094 13.2 0.3 0.68 10.4 0.1 2.3 2 0 0 2 2 2 0 ABC transporter Rab5ip PF07019.12 EGO53761.1 - 1.9e-18 66.8 0.2 2.3e-18 66.6 0.2 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Vezatin PF12632.7 EGO53762.1 - 2.8e-81 273.0 0.0 4.3e-81 272.3 0.0 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF2157 PF09925.9 EGO53762.1 - 0.012 15.4 1.3 0.025 14.4 1.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) GtrA PF04138.14 EGO53762.1 - 0.061 13.6 3.4 0.061 13.6 1.9 1.7 2 0 0 2 2 2 0 GtrA-like protein DUF4381 PF14316.6 EGO53762.1 - 0.26 11.5 5.0 0.23 11.7 1.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) PCNA_N PF00705.18 EGO53763.1 - 7.1e-57 190.6 5.2 2.1e-56 189.1 4.5 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EGO53763.1 - 6.7e-52 175.0 0.8 6.5e-51 171.8 0.1 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EGO53763.1 - 2.1e-08 33.9 0.8 2.4e-08 33.7 0.8 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 EGO53763.1 - 2.9e-06 26.6 3.5 0.00015 21.0 3.5 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 EGO53763.1 - 3.1e-05 23.2 0.5 0.00047 19.4 0.1 2.1 2 0 0 2 2 2 1 Hus1-like protein DUF5384 PF17358.2 EGO53764.1 - 0.0012 18.9 7.6 0.01 15.9 0.0 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5384) dUTPase PF00692.19 EGO53765.1 - 1.1e-45 154.4 0.0 1.3e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 EGO53765.1 - 0.015 14.1 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) CENP-K PF11802.8 EGO53766.1 - 1.1e-12 48.1 4.1 3.9e-07 29.9 0.0 2.4 3 0 0 3 3 3 2 Centromere-associated protein K SlyX PF04102.12 EGO53766.1 - 0.027 15.1 11.0 0.96 10.1 5.2 3.3 3 1 0 3 3 3 0 SlyX DUF948 PF06103.11 EGO53766.1 - 0.11 12.8 1.4 30 5.0 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Mlp PF03304.13 EGO53766.1 - 0.32 11.2 5.9 0.068 13.4 1.4 2.0 2 0 0 2 2 2 0 Mlp lipoprotein family tRNA-synt_1c PF00749.21 EGO53766.1 - 0.36 9.7 3.7 0.66 8.8 3.7 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Fib_alpha PF08702.10 EGO53766.1 - 1.5 9.0 8.4 17 5.6 0.1 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.11 EGO53766.1 - 1.5 9.4 12.6 0.27 11.8 1.1 3.4 2 1 2 4 4 4 0 Syntaxin 6, N-terminal REC1 PF18501.1 EGO53766.1 - 5.1 6.9 10.1 1.1 9.1 4.1 2.2 2 0 0 2 2 2 0 Alpha helical recognition lobe domain FapA PF03961.13 EGO53766.1 - 5.7 5.4 13.5 0.34 9.5 5.1 2.5 3 0 0 3 3 3 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 EGO53766.1 - 7.2 6.1 12.6 0.73 9.3 7.8 1.7 2 1 0 2 2 2 0 Exonuclease VII, large subunit KH_1 PF00013.29 EGO53767.1 - 4.3e-44 148.2 6.3 4.6e-18 64.8 0.6 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EGO53767.1 - 6.5e-13 48.3 4.5 0.0045 16.8 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EGO53767.1 - 1.3e-06 28.1 0.5 0.31 10.9 0.2 3.3 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 EGO53767.1 - 3.1e-05 23.9 0.0 0.046 13.7 0.0 3.1 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 EGO53767.1 - 0.00033 20.7 8.7 0.33 11.0 0.3 3.4 3 0 0 3 3 3 3 NusA-like KH domain PsaN PF05479.11 EGO53768.1 - 0.21 11.8 1.9 0.27 11.4 1.0 1.6 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) DUF3682 PF12446.8 EGO53769.1 - 4.9 7.7 13.3 7.1 7.1 13.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) PAPS_reduct PF01507.19 EGO53770.1 - 6e-29 101.3 0.0 1.6e-20 73.8 0.0 2.3 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family IBR PF01485.21 EGO53772.1 - 1.5e-08 34.7 28.0 3.6e-07 30.3 4.7 3.5 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain DUF853 PF05872.12 EGO53772.1 - 0.1 11.1 0.4 0.15 10.6 0.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF1275 PF06912.11 EGO53773.1 - 4.2e-38 131.2 12.6 5.2e-38 130.9 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Cys_Met_Meta_PP PF01053.20 EGO53774.1 - 4e-137 456.8 0.2 4.6e-137 456.6 0.2 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGO53774.1 - 1.1e-06 28.0 0.2 1.9e-06 27.3 0.2 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGO53774.1 - 8e-06 25.0 0.5 1.3e-05 24.3 0.5 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGO53774.1 - 0.0014 18.0 0.5 0.003 16.9 0.5 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Zn_clus PF00172.18 EGO53776.1 - 3.9e-08 33.3 10.3 6.5e-08 32.6 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGO53776.1 - 3.3e-05 22.9 1.0 6.8e-05 21.8 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Brix PF04427.18 EGO53777.1 - 7e-43 147.0 0.4 1e-42 146.4 0.4 1.2 1 0 0 1 1 1 1 Brix domain DUF1765 PF08578.10 EGO53779.1 - 3.2e-46 156.8 5.9 5.3e-46 156.1 5.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Metallophos_C PF14008.6 EGO53779.1 - 0.087 13.7 0.0 0.23 12.3 0.0 1.7 1 0 0 1 1 1 0 Iron/zinc purple acid phosphatase-like protein C USP19_linker PF16602.5 EGO53779.1 - 0.12 13.0 3.1 0.52 10.9 3.1 2.1 1 0 0 1 1 1 0 Linker region of USP19 deubiquitinase DEAD PF00270.29 EGO53780.1 - 3.3e-20 72.6 0.0 3.3e-20 72.6 0.0 3.9 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO53780.1 - 3.6e-19 69.1 0.1 3.8e-17 62.6 0.1 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EGO53780.1 - 2.2e-16 60.3 6.2 2.2e-16 60.3 6.2 4.3 2 1 0 2 2 2 1 RecQ zinc-binding HRDC PF00570.23 EGO53780.1 - 6.1e-05 22.9 0.0 0.00021 21.2 0.0 2.0 1 0 0 1 1 1 1 HRDC domain Mem_trans PF03547.18 EGO53780.1 - 9 4.6 8.1 6.4 5.1 5.7 1.9 2 0 0 2 2 2 0 Membrane transport protein DUF2715 PF10895.8 EGO53781.1 - 0.089 12.4 2.7 0.12 12.0 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2715) KAR9 PF08580.10 EGO53783.1 - 1.7e-206 687.9 4.2 1.7e-206 687.9 4.2 3.8 2 2 1 4 4 4 1 Yeast cortical protein KAR9 Prominin PF05478.11 EGO53783.1 - 1.1 7.2 2.8 1.1 7.1 0.5 1.9 2 0 0 2 2 2 0 Prominin Yip1 PF04893.17 EGO53785.1 - 0.00011 21.9 0.2 0.00013 21.8 0.2 1.0 1 0 0 1 1 1 1 Yip1 domain Sdh_cyt PF01127.22 EGO53785.1 - 0.045 13.8 0.1 0.057 13.5 0.1 1.1 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4131 PF13567.6 EGO53785.1 - 0.15 11.7 0.2 0.17 11.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) NUP214 PF16755.5 EGO53787.1 - 6.5e-05 22.3 0.0 0.00019 20.8 0.0 1.6 2 0 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 EGO53787.1 - 0.00046 20.4 0.0 0.0084 16.4 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_FG PF13634.6 EGO53787.1 - 0.0014 19.4 1.6 0.0014 19.4 1.6 7.1 3 2 4 7 7 7 3 Nucleoporin FG repeat region DUF4194 PF13835.6 EGO53787.1 - 0.15 11.8 3.0 0.29 10.9 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) CDC45 PF02724.14 EGO53787.1 - 3.9 5.6 21.6 6.7 4.9 21.6 1.2 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.11 EGO53787.1 - 4 7.1 35.4 12 5.5 35.4 1.9 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Proteasome PF00227.26 EGO53788.1 - 3.6e-46 157.1 0.0 4.7e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EGO53788.1 - 1.3e-14 53.3 0.8 1.3e-14 53.3 0.8 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Sel1 PF08238.12 EGO53789.1 - 1e-09 38.7 14.2 0.0023 18.6 0.1 4.2 5 0 0 5 5 5 3 Sel1 repeat COPIIcoated_ERV PF07970.12 EGO53790.1 - 7.7e-85 284.2 0.0 1.5e-84 283.3 0.0 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGO53790.1 - 2.1e-30 104.9 0.0 3.8e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Per1 PF04080.13 EGO53792.1 - 1.9e-103 345.7 9.0 2.3e-103 345.4 9.0 1.1 1 0 0 1 1 1 1 Per1-like family DUF3522 PF12036.8 EGO53792.1 - 0.0082 16.4 4.1 0.014 15.6 4.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) 7TMR-DISM_7TM PF07695.11 EGO53792.1 - 3.1 7.6 11.5 34 4.2 11.5 2.2 1 1 0 1 1 1 0 7TM diverse intracellular signalling Serglycin PF04360.12 EGO53793.1 - 0.16 11.9 0.9 0.3 11.0 0.9 1.4 1 0 0 1 1 1 0 Serglycin Ppx-GppA PF02541.16 EGO53794.1 - 1.5e-28 100.1 0.0 2.3e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Tyrosinase PF00264.20 EGO53798.1 - 9.2e-49 166.7 0.5 1.3e-48 166.2 0.5 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EGO53798.1 - 2.7e-34 118.4 0.0 4.8e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain RNA_pol_Rpb2_6 PF00562.28 EGO53799.1 - 3.1e-113 378.8 0.1 4.2e-113 378.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGO53799.1 - 2.1e-35 122.1 0.0 3.7e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EGO53799.1 - 1.2e-28 99.1 0.0 2.6e-28 98.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 EGO53799.1 - 1e-26 92.7 0.0 2.1e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 EGO53799.1 - 2.1e-25 89.5 0.0 4.8e-25 88.3 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EGO53799.1 - 2.5e-15 56.7 0.0 9.8e-14 51.5 0.0 2.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 zinc_ribbon_15 PF17032.5 EGO53799.1 - 0.08 13.7 0.2 0.2 12.4 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon family Arf PF00025.21 EGO53800.1 - 7.2e-43 146.0 0.0 8.4e-43 145.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGO53800.1 - 2.9e-19 69.3 0.0 3.7e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO53800.1 - 5.5e-15 55.6 0.0 7.8e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGO53800.1 - 1.5e-07 31.1 0.0 1.8e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGO53800.1 - 5.7e-07 29.1 0.0 7.1e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGO53800.1 - 3.4e-06 27.1 0.0 4.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGO53800.1 - 3.4e-05 23.2 0.1 0.00022 20.5 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit DUF1979 PF09322.10 EGO53800.1 - 0.039 13.8 0.3 6.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) MMR_HSR1_Xtn PF16897.5 EGO53800.1 - 0.083 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 EGO53800.1 - 0.093 12.3 0.2 0.21 11.1 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Ribosomal_S9 PF00380.19 EGO53801.1 - 1e-34 119.6 0.3 1.2e-34 119.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 RCR PF12273.8 EGO53802.1 - 1e-22 81.0 10.1 1.3e-22 80.7 10.1 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red UDPGT PF00201.18 EGO53806.1 - 6.6e-07 28.5 0.0 9e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EGO53806.1 - 0.00063 19.8 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain FAD_binding_7 PF03441.14 EGO53807.1 - 4e-78 261.5 0.0 8e-78 260.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EGO53807.1 - 9.6e-37 126.5 0.0 1.8e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Gal_mutarotas_2 PF13802.6 EGO53807.1 - 0.072 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Galactose mutarotase-like Ribosomal_S21e PF01249.18 EGO53808.1 - 1.6e-37 127.5 0.1 1.8e-37 127.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Slx4 PF09494.10 EGO53809.1 - 1.5e-24 85.7 0.1 2.7e-24 84.9 0.1 1.5 1 0 0 1 1 1 1 Slx4 endonuclease WD40 PF00400.32 EGO53813.1 - 5.7e-10 39.6 12.9 0.00015 22.5 1.8 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO53813.1 - 0.01 16.1 0.1 0.25 11.6 0.1 3.2 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGO53813.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A zf-CHY PF05495.12 EGO53813.1 - 0.15 12.6 3.3 0.36 11.4 3.3 1.6 1 0 0 1 1 1 0 CHY zinc finger zf-CW PF07496.15 EGO53813.1 - 1.5 8.9 5.9 5.2 7.2 5.9 1.8 1 0 0 1 1 1 0 CW-type Zinc Finger zf-RING_9 PF13901.6 EGO53813.1 - 1.6 8.6 4.2 0.58 10.1 0.5 1.9 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon PHD PF00628.29 EGO53813.1 - 5.1 7.1 9.5 6.8 6.7 0.4 2.9 2 1 1 3 3 3 0 PHD-finger Zn_Tnp_IS1595 PF12760.7 EGO53813.1 - 8.8 6.4 8.1 0.33 10.9 1.0 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Cactin_mid PF10312.9 EGO53814.1 - 2.5e-65 219.9 7.4 3.4e-65 219.5 7.4 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 EGO53814.1 - 4.6e-58 194.6 4.6 7.9e-58 193.8 4.6 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 EGO53814.1 - 0.034 14.5 0.0 0.099 13.0 0.0 1.8 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DUF1087 PF06465.13 EGO53814.1 - 0.054 13.5 3.6 0.096 12.7 0.2 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) HNH_2 PF13391.6 EGO53815.1 - 0.076 13.2 0.1 0.092 12.9 0.1 1.1 1 0 0 1 1 1 0 HNH endonuclease Forkhead PF00250.18 EGO53816.1 - 1.9e-22 79.3 0.4 4.8e-22 78.0 0.4 1.7 1 0 0 1 1 1 1 Forkhead domain Spt20 PF12090.8 EGO53816.1 - 0.003 17.2 28.3 0.003 17.2 28.3 2.3 2 0 0 2 2 2 1 Spt20 family ORC_WH_C PF18137.1 EGO53816.1 - 0.039 14.0 16.8 0.65 10.1 0.4 2.6 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal DUF4820 PF16091.5 EGO53816.1 - 0.29 10.5 10.1 0.73 9.2 5.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) FYDLN_acid PF09538.10 EGO53816.1 - 0.68 10.6 10.6 0.14 12.9 4.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF775 PF05603.12 EGO53816.1 - 0.71 9.4 10.6 1.8 8.1 10.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Eapp_C PF10238.9 EGO53816.1 - 0.72 9.9 11.6 0.087 12.9 4.2 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein EPL1 PF10513.9 EGO53816.1 - 1.3 9.3 17.6 0.18 12.2 7.2 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like RasGEF_N PF00618.20 EGO53816.1 - 1.6 9.0 4.7 12 6.2 1.4 2.5 2 0 0 2 2 2 0 RasGEF N-terminal motif RR_TM4-6 PF06459.12 EGO53816.1 - 2.3 7.9 12.8 0.39 10.5 5.3 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF853 PF05872.12 EGO53816.1 - 2.5 6.6 6.5 4.2 5.8 6.5 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF4175 PF13779.6 EGO53816.1 - 2.9 5.7 24.8 5.2 4.9 24.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3533 PF12051.8 EGO53816.1 - 3.3 6.5 7.9 5.7 5.7 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) PepSY_TM PF03929.16 EGO53816.1 - 3.5 7.2 6.4 7.8 6.1 6.4 1.5 1 0 0 1 1 1 0 PepSY-associated TM region DUF4199 PF13858.6 EGO53816.1 - 3.6 8.0 8.2 6.1 7.2 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) TERB2 PF15101.6 EGO53816.1 - 3.6 7.6 17.5 0.22 11.6 11.8 1.8 2 0 0 2 2 2 0 Telomere-associated protein TERB2 CDC24_OB1 PF17246.2 EGO53816.1 - 4.8 7.3 8.3 0.94 9.6 3.3 2.2 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 1 Connexin PF00029.19 EGO53816.1 - 6.5 6.4 10.0 2.1 8.0 4.3 2.1 2 0 0 2 2 2 0 Connexin FAM176 PF14851.6 EGO53816.1 - 7.4 6.2 11.5 5.6 6.6 4.6 2.3 2 0 0 2 2 2 0 FAM176 family Peptidase_C74 PF12387.8 EGO53817.1 - 0.17 11.3 0.0 0.18 11.2 0.0 1.0 1 0 0 1 1 1 0 Pestivirus NS2 peptidase XLF PF09302.11 EGO53819.1 - 2e-55 187.7 0.0 3.1e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component AAA PF00004.29 EGO53823.1 - 8.6e-16 58.6 0.0 1.8e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO53823.1 - 1e-05 25.8 1.3 0.042 14.1 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGO53823.1 - 0.00014 22.3 0.1 0.00053 20.4 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGO53823.1 - 0.0053 16.5 0.0 0.0098 15.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 EGO53823.1 - 0.0061 16.9 0.0 0.04 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGO53823.1 - 0.032 14.2 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) cNMP_binding PF00027.29 EGO53824.1 - 1.6e-35 121.0 0.0 1.8e-18 66.3 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 EGO53824.1 - 1.5e-21 77.5 28.3 2.2e-19 70.4 9.9 3.1 2 1 1 3 3 3 2 Unstructured region on cNMP-binding protein LRR_6 PF13516.6 EGO53824.1 - 1.7e-10 40.0 4.6 0.14 12.3 0.1 6.8 8 0 0 8 8 8 3 Leucine Rich repeat F-box PF00646.33 EGO53824.1 - 1.3e-08 34.5 4.0 1.3e-08 34.5 4.0 3.1 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EGO53824.1 - 6.1e-08 32.4 3.2 6.1e-08 32.4 3.2 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EGO53824.1 - 2e-07 31.2 2.7 0.0019 18.5 0.1 4.8 4 1 4 8 8 8 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGO53824.1 - 0.00069 19.8 4.8 30 5.7 0.0 6.9 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 EGO53824.1 - 0.023 14.5 0.2 13 5.6 0.0 3.3 2 1 0 2 2 2 0 Leucine rich repeat Cupin_3 PF05899.12 EGO53824.1 - 0.08 12.6 0.1 4.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DUF3433 PF11915.8 EGO53826.1 - 1.2e-20 73.7 0.3 1.2e-20 73.7 0.3 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3433) Kelch_5 PF13854.6 EGO53826.1 - 4.2e-12 45.8 0.2 7.1e-11 41.8 0.1 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 EGO53826.1 - 0.0011 19.0 0.8 0.0067 16.4 0.1 2.4 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.6 EGO53826.1 - 0.025 14.8 0.8 0.13 12.6 0.1 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.25 EGO53826.1 - 0.075 12.6 2.9 0.74 9.5 0.1 3.3 3 0 0 3 3 3 0 Kelch motif Bax1-I PF01027.20 EGO53827.1 - 2.6e-36 125.4 10.9 3.9e-36 124.8 10.9 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 COX14 PF14880.6 EGO53827.1 - 0.17 11.7 1.9 0.78 9.6 1.9 2.1 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Rox3 PF08633.10 EGO53831.1 - 6.7e-69 232.3 0.1 6.7e-69 232.3 0.1 1.9 2 1 0 2 2 2 1 Rox3 mediator complex subunit DUF4939 PF16297.5 EGO53832.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Spt20 PF12090.8 EGO53833.1 - 0.34 10.5 5.9 0.3 10.7 5.9 1.2 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 EGO53833.1 - 0.85 8.7 8.6 0.86 8.7 8.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.13 EGO53833.1 - 3.2 7.7 8.9 3.3 7.6 8.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5314 PF17241.2 EGO53839.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5314) Abhydrolase_6 PF12697.7 EGO53840.1 - 3.1e-09 37.7 0.1 4.8e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO53840.1 - 2.2e-05 24.2 0.0 3.4e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO53840.1 - 0.00018 20.9 0.4 0.056 12.7 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EGO53840.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 EGO53840.1 - 0.084 12.6 1.2 0.25 11.0 0.3 1.9 2 0 0 2 2 2 0 PGAP1-like protein DUF2974 PF11187.8 EGO53840.1 - 0.19 11.2 0.1 0.3 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DBR1 PF05011.13 EGO53841.1 - 2.2e-41 141.5 0.0 4.9e-41 140.4 0.0 1.6 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EGO53841.1 - 4e-05 24.2 1.4 6.3e-05 23.6 1.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MatE PF01554.18 EGO53844.1 - 2e-55 186.8 18.4 1.4e-27 96.3 6.6 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EGO53844.1 - 1.4e-05 25.2 10.2 1.4e-05 25.2 10.2 4.0 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain DUF679 PF05078.12 EGO53844.1 - 0.15 12.0 1.3 3.3 7.6 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF679) UPF0052 PF01933.18 EGO53845.1 - 1.2e-42 146.2 0.0 1.2e-39 136.3 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family UPF0052 Alpha_kinase PF02816.18 EGO53846.1 - 2.3e-51 174.5 0.0 3.5e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 EGO53846.1 - 1.7e-10 41.5 0.0 4.6e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EGO53846.1 - 0.00033 21.0 0.0 0.00055 20.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain TssR PF17643.1 EGO53846.1 - 0.2 9.6 0.0 0.31 8.9 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssR Pkinase PF00069.25 EGO53849.1 - 2.1e-41 142.0 0.1 1.9e-23 83.2 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO53849.1 - 2.7e-14 53.1 0.3 1.2e-09 37.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO53849.1 - 0.089 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PMSI1 PF15322.6 EGO53850.1 - 0.43 10.0 7.8 0.57 9.6 7.8 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative SRP-alpha_N PF04086.13 EGO53850.1 - 0.5 10.2 15.6 0.68 9.8 15.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 EGO53850.1 - 0.68 8.6 13.5 0.82 8.4 13.5 1.2 1 0 0 1 1 1 0 Presenilin CCDC53 PF10152.9 EGO53850.1 - 0.75 10.2 17.3 2.7 8.4 9.1 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex SOG2 PF10428.9 EGO53850.1 - 1.4 8.1 9.7 1.6 7.8 9.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PRKCSH PF07915.13 EGO53850.1 - 1.6 9.8 9.1 3.5 8.7 2.2 2.5 2 1 0 2 2 2 0 Glucosidase II beta subunit-like protein Cwf_Cwc_15 PF04889.12 EGO53850.1 - 2.2 7.9 17.6 0.16 11.7 10.9 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Dicty_REP PF05086.12 EGO53850.1 - 2.8 5.8 8.4 3.5 5.5 8.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pox_Ag35 PF03286.14 EGO53850.1 - 2.8 7.7 16.3 5.7 6.7 16.3 1.6 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Spt5_N PF11942.8 EGO53850.1 - 3.1 8.8 23.4 3 8.9 6.8 2.2 1 1 1 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal eIF3_subunit PF08597.10 EGO53850.1 - 3.8 7.4 18.5 0.25 11.2 8.8 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Suf PF05843.14 EGO53850.1 - 7.4 6.5 14.4 4.7 7.1 6.9 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RabGAP-TBC PF00566.18 EGO53851.1 - 1e-43 149.5 0.0 7.1e-43 146.8 0.0 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF594 PF04578.13 EGO53852.1 - 0.19 11.3 0.2 0.26 10.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF594 tRNA_synthFbeta PF17759.1 EGO53853.1 - 1.3e-44 152.2 0.0 2e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EGO53853.1 - 2.2e-28 98.3 0.4 9.9e-27 93.0 0.1 2.6 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EGO53853.1 - 5.3e-26 91.3 0.0 8.6e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EGO53853.1 - 5.6e-18 65.0 0.0 2.3e-15 56.6 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetase B5 domain Beta-TrCP_D PF12125.8 EGO53854.1 - 1.6 8.7 4.2 3 7.8 4.2 1.4 1 0 0 1 1 1 0 D domain of beta-TrCP tRNA-synt_1b PF00579.25 EGO53856.1 - 3.1e-19 69.4 0.6 6.6e-19 68.3 0.0 1.8 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) 2CSK_N PF08521.10 EGO53856.1 - 0.0002 21.5 0.1 0.00032 20.8 0.1 1.3 1 0 0 1 1 1 1 Two-component sensor kinase N-terminal DUF3242 PF11586.8 EGO53856.1 - 0.054 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) DUF3435 PF11917.8 EGO53857.1 - 3.8e-15 55.7 0.1 4.8e-15 55.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Defensin_1 PF00323.19 EGO53857.1 - 0.053 14.1 2.0 0.14 12.8 2.0 1.7 1 0 0 1 1 1 0 Mammalian defensin zf-CCHC PF00098.23 EGO53858.1 - 5.7e-05 23.0 2.1 0.00011 22.1 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGO53858.1 - 5.9e-05 22.8 2.2 0.0001 22.0 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle Chorion_2 PF03964.15 EGO53858.1 - 0.0051 17.6 0.8 0.007 17.2 0.8 1.2 1 0 0 1 1 1 1 Chorion family 2 zf-CCHC_4 PF14392.6 EGO53858.1 - 0.1 12.4 0.9 0.21 11.4 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle PARP PF00644.20 EGO53860.1 - 1.2e-61 207.7 0.0 2e-61 207.0 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EGO53860.1 - 3.8e-46 156.6 0.4 5.7e-46 156.0 0.4 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EGO53860.1 - 6.7e-14 51.7 0.5 1.9e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 WGR domain SWIRM-assoc_2 PF16496.5 EGO53860.1 - 4.5e-05 22.5 0.2 9.3e-05 21.5 0.2 1.4 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal Exonuc_VII_L PF02601.15 EGO53861.1 - 0.039 13.5 6.2 0.1 12.1 0.7 2.9 3 0 0 3 3 3 0 Exonuclease VII, large subunit DUF2935 PF11155.8 EGO53861.1 - 2 8.7 12.5 15 5.9 4.4 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF2935) Phage_HK97_TLTM PF06120.11 EGO53861.1 - 9.6 5.3 16.9 0.75 8.9 3.3 2.9 3 0 0 3 3 3 0 Tail length tape measure protein APG6_N PF17675.1 EGO53862.1 - 0.011 16.3 1.5 0.011 16.3 1.5 2.5 3 0 0 3 3 2 0 Apg6 coiled-coil region Cortex-I_coil PF09304.10 EGO53862.1 - 0.017 15.3 0.4 0.017 15.3 0.4 3.7 4 1 1 5 5 5 0 Cortexillin I, coiled coil Uds1 PF15456.6 EGO53862.1 - 0.04 14.1 2.7 0.11 12.7 0.8 2.4 1 1 0 2 2 2 0 Up-regulated During Septation FTA4 PF13093.6 EGO53862.1 - 0.092 12.6 3.4 0.29 11.0 3.4 1.9 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Syntaxin-6_N PF09177.11 EGO53862.1 - 0.097 13.2 5.1 1.9 9.1 0.8 3.5 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Cdc13_OB2 PF18691.1 EGO53862.1 - 0.1 12.6 0.1 0.61 10.2 0.1 2.1 2 0 0 2 2 2 0 Cell division control protein 13, OB2 domain Spc7 PF08317.11 EGO53862.1 - 0.14 11.0 10.8 1.1 8.1 5.6 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF16 PF01519.16 EGO53862.1 - 0.19 12.2 13.9 0.041 14.4 3.3 3.6 2 1 2 4 4 4 0 Protein of unknown function DUF16 Tropomyosin PF00261.20 EGO53862.1 - 0.31 10.4 10.0 1.3 8.3 0.5 3.1 2 1 0 2 2 2 0 Tropomyosin FlaC_arch PF05377.11 EGO53862.1 - 0.35 11.3 7.9 1.4 9.3 1.1 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) MscS_porin PF12795.7 EGO53862.1 - 0.52 9.8 19.7 0.92 9.0 3.3 3.3 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain COG2 PF06148.11 EGO53862.1 - 0.66 10.1 7.4 5.9 7.0 0.8 3.6 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 CCDC144C PF14915.6 EGO53862.1 - 1.8 7.6 11.9 2.9 6.9 0.1 3.0 3 1 0 3 3 3 0 CCDC144C protein coiled-coil region Lebercilin PF15619.6 EGO53862.1 - 2.2 7.9 12.7 1.1 8.9 3.5 2.8 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Sec34 PF04136.15 EGO53862.1 - 3.4 7.5 9.1 1.6 8.6 1.3 3.2 4 0 0 4 4 4 0 Sec34-like family Exonuc_VII_L PF02601.15 EGO53862.1 - 3.5 7.1 9.9 11 5.5 9.9 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit NPV_P10 PF05531.12 EGO53862.1 - 3.7 8.1 13.3 23 5.5 0.1 4.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.6 EGO53862.1 - 5 6.8 11.7 1.1 9.0 0.7 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4201) Muted PF14942.6 EGO53862.1 - 7.3 6.9 12.3 1.2 9.4 4.4 3.0 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein Fez1 PF06818.15 EGO53862.1 - 7.8 6.9 11.4 19 5.6 9.1 2.6 1 1 2 3 3 3 0 Fez1 Fib_alpha PF08702.10 EGO53862.1 - 9.5 6.4 14.6 1.6 8.9 6.1 3.5 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family TolA_bind_tri PF16331.5 EGO53862.1 - 9.5 6.4 15.6 3.7 7.7 3.4 3.6 3 1 0 3 3 3 0 TolA binding protein trimerisation PAN_4 PF14295.6 EGO53865.1 - 0.0036 17.2 0.5 0.0085 16.0 0.5 1.7 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 EGO53865.1 - 0.007 16.1 0.4 0.015 15.0 0.4 1.5 1 0 0 1 1 1 1 PAN-like domain PAN_1 PF00024.26 EGO53865.1 - 0.0084 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 PAN domain B277 PF17623.2 EGO53865.1 - 0.03 13.4 1.4 0.047 12.8 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function Sporozoite_P67 PF05642.11 EGO53865.1 - 0.093 10.8 3.5 0.12 10.5 3.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YjbE PF11106.8 EGO53865.1 - 5.5 7.3 17.2 0.71 10.1 10.1 2.5 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE ABC2_membrane PF01061.24 EGO53866.1 - 3.9e-22 78.7 26.7 5.7e-22 78.2 26.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGO53866.1 - 7.8e-14 52.3 0.0 1.5e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGO53866.1 - 0.00063 19.7 0.2 0.0018 18.2 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGO53866.1 - 0.0033 17.8 0.4 0.017 15.5 0.4 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGO53866.1 - 0.0043 17.3 0.0 0.0081 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EGO53866.1 - 0.082 12.7 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 EGO53866.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.6 2 1 1 3 3 3 0 CDR ABC transporter MtrG PF04210.13 EGO53866.1 - 0.18 11.7 0.2 0.65 9.9 0.2 1.9 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G SIR2 PF02146.17 EGO53867.1 - 2.7e-59 200.1 0.0 7.5e-59 198.6 0.0 1.8 1 1 0 1 1 1 1 Sir2 family DUF592 PF04574.13 EGO53867.1 - 2.1e-05 24.4 0.1 4.9e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 EGO53867.1 - 0.00025 20.8 0.0 0.57 9.9 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF2201_N PF13203.6 EGO53867.1 - 0.022 14.4 2.0 0.042 13.4 0.4 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain Peptidase_C7 PF01830.18 EGO53867.1 - 0.1 12.0 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase C7 family Zn_ribbon_SprT PF17283.2 EGO53867.1 - 0.25 11.3 1.2 0.51 10.3 1.2 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Atrophin-1 PF03154.15 EGO53867.1 - 4.1 5.6 16.3 8.3 4.6 16.3 1.5 1 0 0 1 1 1 0 Atrophin-1 family Med9 PF07544.13 EGO53868.1 - 0.096 12.8 3.1 0.59 10.2 0.4 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 AMP-binding PF00501.28 EGO53869.1 - 3.7e-75 253.1 0.0 4.9e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO53869.1 - 2.7e-10 41.1 1.6 8.4e-10 39.5 0.3 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AhpC-TSA PF00578.21 EGO53871.1 - 2e-29 102.1 0.0 2.6e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGO53871.1 - 3.1e-11 43.2 0.0 4.1e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGO53871.1 - 1.4e-10 40.8 0.1 2.8e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin GSHPx PF00255.19 EGO53871.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione peroxidase Vac7 PF12751.7 EGO53872.1 - 6.2e-114 381.4 52.5 3.9e-71 240.5 14.4 4.2 2 1 2 4 4 4 3 Vacuolar segregation subunit 7 BRCT_2 PF16589.5 EGO53873.1 - 1.8e-08 34.7 0.0 3.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EGO53873.1 - 7.2e-05 22.7 1.2 0.00031 20.6 0.0 2.5 3 0 0 3 3 3 1 twin BRCT domain BRCT PF00533.26 EGO53873.1 - 0.0036 17.6 0.0 0.0078 16.6 0.0 1.6 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PBP PF01161.20 EGO53874.1 - 1.6e-11 44.6 0.0 2.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF2064 PF09837.9 EGO53874.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) Ribosomal_L4 PF00573.22 EGO53875.1 - 2.6e-42 144.7 0.0 4e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Glyco_transf_34 PF05637.12 EGO53877.1 - 1e-14 54.9 0.0 7.8e-12 45.4 0.0 2.5 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family RR_TM4-6 PF06459.12 EGO53877.1 - 0.11 12.3 16.2 0.21 11.4 16.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 EGO53877.1 - 0.37 10.9 7.4 0.76 9.9 7.4 1.4 1 0 0 1 1 1 0 DDHD domain Hox9_act PF04617.13 EGO53877.1 - 6.7 7.4 10.1 15 6.3 10.1 1.5 1 0 0 1 1 1 0 Hox9 activation region Vfa1 PF08432.10 EGO53877.1 - 8 6.7 24.7 15 5.9 24.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sld5 PF05916.11 EGO53879.1 - 2e-21 76.5 0.0 2.8e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Sod_Fe_C PF02777.18 EGO53880.1 - 3.5e-37 126.7 0.2 5.6e-37 126.0 0.2 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGO53880.1 - 1.5e-30 105.5 0.6 6.8e-30 103.4 0.8 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain PRP1_N PF06424.12 EGO53881.1 - 9.9e-49 165.5 7.7 9.9e-49 165.5 7.7 1.8 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 EGO53881.1 - 1.2e-30 105.8 20.1 1.6e-05 25.3 0.1 9.7 7 2 1 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 EGO53881.1 - 5.8e-30 101.4 43.2 0.00088 19.9 0.0 14.4 6 3 9 15 15 14 10 Tetratricopeptide repeat TPR_16 PF13432.6 EGO53881.1 - 2.1e-15 57.1 24.3 2.3e-06 28.1 0.0 8.1 7 1 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGO53881.1 - 9e-15 53.5 18.6 0.11 12.7 0.0 12.3 12 1 1 13 13 12 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO53881.1 - 3.9e-12 45.3 1.6 0.033 14.4 0.0 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGO53881.1 - 2.8e-09 37.0 17.6 1.8e-05 24.8 0.0 7.1 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGO53881.1 - 1.7e-07 31.1 4.7 0.42 11.1 0.0 8.3 9 0 0 9 9 8 1 Tetratricopeptide repeat Suf PF05843.14 EGO53881.1 - 2.4e-07 31.0 0.4 2 8.3 0.0 5.1 5 1 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_15 PF13429.6 EGO53881.1 - 4.9e-07 29.3 24.0 0.0018 17.6 2.4 6.0 2 2 5 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGO53881.1 - 5.5e-07 29.1 0.1 1 9.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.8 EGO53881.1 - 1.8e-06 27.2 10.7 0.079 11.9 0.0 5.7 4 1 3 7 7 7 2 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 EGO53881.1 - 3.2e-05 24.1 12.6 0.89 9.9 0.1 7.2 5 3 2 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGO53881.1 - 0.00017 21.2 6.6 0.011 15.4 0.0 5.6 5 1 1 6 6 6 1 TPR repeat ChAPs PF09295.10 EGO53881.1 - 0.0017 17.4 9.4 0.012 14.6 0.0 3.9 3 1 1 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF3808 PF10300.9 EGO53881.1 - 0.0046 15.8 4.8 2.2 6.9 0.1 4.7 3 1 3 6 6 6 1 Protein of unknown function (DUF3808) TPR_6 PF13174.6 EGO53881.1 - 0.0067 17.0 18.7 34 5.4 0.0 9.7 10 0 0 10 10 9 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EGO53881.1 - 0.013 15.5 4.8 0.074 13.0 0.2 3.6 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal TPR_7 PF13176.6 EGO53881.1 - 0.021 14.8 0.6 9.8 6.5 0.1 4.1 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF3176 PF11374.8 EGO53882.1 - 2.5e-06 27.7 0.1 2.5e-06 27.7 0.1 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF3176) Toxin_20 PF08089.11 EGO53887.1 - 0.19 11.8 0.9 0.43 10.7 0.9 1.5 1 0 0 1 1 1 0 Huwentoxin-II family Glyco_hydro_76 PF03663.14 EGO53888.1 - 6.2e-159 529.4 6.4 7.3e-159 529.1 6.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EGO53888.1 - 0.029 13.5 8.8 0.84 8.6 0.4 3.1 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Gln-synt_C PF00120.24 EGO53889.1 - 1.6e-86 290.4 0.0 2.4e-86 289.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 EGO53889.1 - 5.2e-14 52.7 0.3 1.2e-13 51.5 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase Bac_chlorC PF02043.17 EGO53889.1 - 0.13 12.3 0.0 0.81 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein Membr_traf_MHD PF10540.9 EGO53890.1 - 1.2e-17 64.5 1.9 9.7e-15 55.0 1.0 3.1 2 1 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EGO53890.1 - 9.1e-17 61.2 0.0 2.6e-16 59.8 0.0 1.9 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 EGO53890.1 - 1.1e-07 30.8 0.2 2.2e-07 29.9 0.2 1.5 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) Lactonase PF10282.9 EGO53892.1 - 7.1e-91 305.0 0.1 9.3e-91 304.6 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Nucleotid_trans PF03407.16 EGO53895.1 - 1.5e-08 34.9 0.0 2.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 EGO53895.1 - 0.018 14.8 1.0 0.029 14.1 1.0 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family MFS_1 PF07690.16 EGO53896.1 - 2.8e-35 121.9 16.2 4.2e-35 121.3 16.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 EGO53897.1 - 3.6e-12 45.9 0.0 7.1e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO53897.1 - 1.4e-05 25.1 11.4 2.6e-05 24.2 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IF-2B PF01008.17 EGO53898.1 - 9.6e-17 61.1 0.2 2.3e-16 59.8 0.2 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.28 EGO53898.1 - 1.2e-07 31.8 0.0 2.9e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain PAN_4 PF14295.6 EGO53899.1 - 0.005 16.7 0.5 0.011 15.6 0.5 1.6 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 EGO53899.1 - 0.021 14.6 0.4 0.044 13.6 0.4 1.5 1 0 0 1 1 1 0 PAN-like domain PAN_1 PF00024.26 EGO53899.1 - 0.032 14.2 0.4 0.07 13.1 0.4 1.5 1 0 0 1 1 1 0 PAN domain ArAE_2_N PF10337.9 EGO53899.1 - 0.095 11.7 0.6 0.12 11.4 0.6 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal ABC_tran_2 PF16949.5 EGO53899.1 - 0.3 9.8 0.3 0.41 9.4 0.3 1.1 1 0 0 1 1 1 0 Putative ATP-binding cassette Sugar_tr PF00083.24 EGO53900.1 - 2.8e-69 234.1 12.5 3.4e-69 233.8 12.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO53900.1 - 6.2e-27 94.4 17.0 7.9e-27 94.1 17.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EGO53900.1 - 3.4e-06 25.9 9.1 0.0026 16.4 0.4 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein PTR2 PF00854.21 EGO53900.1 - 0.048 12.5 7.0 0.036 12.9 0.6 2.3 2 0 0 2 2 2 0 POT family Tweety PF04906.13 EGO53900.1 - 0.13 10.9 0.2 0.22 10.1 0.2 1.4 1 1 0 1 1 1 0 Tweety OATP PF03137.20 EGO53900.1 - 6.9 4.8 15.9 0.45 8.7 0.5 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MARVEL PF01284.23 EGO53902.1 - 0.00047 20.2 0.5 0.00062 19.8 0.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.11 EGO53902.1 - 0.018 15.0 4.7 0.023 14.6 4.7 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF5504 PF17608.2 EGO53902.1 - 0.17 12.0 5.8 0.2 11.8 4.3 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5504) F-box-like PF12937.7 EGO53903.1 - 0.00061 19.6 0.2 0.0041 17.0 0.0 2.6 2 1 0 2 2 2 1 F-box-like Glyco_hydro_16 PF00722.21 EGO53904.1 - 4e-10 39.5 1.2 6.9e-10 38.7 1.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CBM_1 PF00734.18 EGO53904.1 - 5.2e-10 39.1 13.7 1.4e-09 37.7 13.7 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Lactamase_B PF00753.27 EGO53905.1 - 2.1e-07 31.1 0.5 5.6e-07 29.8 0.1 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGO53905.1 - 2.4e-05 23.9 0.8 0.0011 18.5 0.1 2.6 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Methyltransf_23 PF13489.6 EGO53907.1 - 1.3e-11 44.6 0.0 2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO53907.1 - 3.6e-10 39.8 0.0 3.4e-09 36.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO53907.1 - 6.8e-10 39.5 0.0 2.2e-09 37.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO53907.1 - 1e-08 35.8 0.0 4.9e-08 33.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EGO53907.1 - 1.3e-06 28.6 0.0 1.8e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 EGO53907.1 - 1.8e-06 28.5 0.0 6.6e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGO53907.1 - 0.00039 19.9 0.0 0.00066 19.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EGO53907.1 - 0.00072 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EGO53907.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EGO53907.1 - 0.018 14.3 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 EGO53907.1 - 0.033 13.5 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EGO53907.1 - 0.059 12.7 0.0 0.078 12.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FF PF01846.19 EGO53908.1 - 4.4e-07 30.0 12.6 4.8e-06 26.7 0.1 5.0 4 2 0 4 4 4 2 FF domain DUF2207 PF09972.9 EGO53908.1 - 1.7 7.3 3.8 0.85 8.3 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Glyco_hydro_10 PF00331.20 EGO53909.1 - 1.4e-83 280.7 0.0 1.7e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 AA_permease PF00324.21 EGO53910.1 - 3.9e-137 457.7 34.5 4.6e-137 457.5 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO53910.1 - 2.6e-32 112.2 38.4 3.7e-32 111.7 38.4 1.2 1 0 0 1 1 1 1 Amino acid permease DLH PF01738.18 EGO53911.1 - 2.1e-28 99.4 0.0 2.5e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_M42 PF05343.14 EGO53911.1 - 0.0052 15.8 0.0 0.0073 15.3 0.0 1.1 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Acetyltransf_1 PF00583.25 EGO53912.1 - 7.3e-07 29.4 0.0 9.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO53912.1 - 3.5e-06 27.3 0.0 5.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGO53912.1 - 3.4e-05 23.8 0.0 9.6e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGO53912.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF747 PF05346.11 EGO53913.1 - 1.1e-120 402.9 1.0 1.4e-120 402.6 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF4834 PF16118.5 EGO53913.1 - 0.043 14.8 0.5 6.9 7.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) TRI5 PF06330.11 EGO53914.1 - 7.4e-06 25.1 0.1 0.046 12.6 0.0 2.1 2 0 0 2 2 2 2 Trichodiene synthase (TRI5) ING PF12998.7 EGO53914.1 - 0.018 15.6 0.1 0.64 10.6 0.0 2.6 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4530 PF15039.6 EGO53917.1 - 4 7.6 6.4 7.4 6.8 2.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) AMP-binding PF00501.28 EGO53918.1 - 1.7e-219 728.6 0.0 3.9e-78 262.9 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EGO53918.1 - 1.3e-178 594.4 0.0 3.2e-35 121.7 0.0 7.3 7 0 0 7 7 7 7 Condensation domain PP-binding PF00550.25 EGO53918.1 - 6.6e-59 196.2 9.0 7e-10 39.1 0.0 7.4 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGO53918.1 - 4.7e-12 46.7 1.0 0.00028 21.8 0.4 4.8 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 EGO53918.1 - 0.0006 19.7 1.0 11 5.7 0.0 4.8 5 0 0 5 5 5 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.15 EGO53918.1 - 0.027 13.1 1.1 1.4 7.5 0.0 3.6 4 0 0 4 4 4 0 Transferase family K_oxygenase PF13434.6 EGO53919.1 - 6.8e-109 364.1 0.0 1.4e-108 363.1 0.0 1.5 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EGO53919.1 - 1.8e-06 27.4 0.0 7e-05 22.2 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO53919.1 - 1.8e-05 24.2 0.0 8.4e-05 22.0 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HECW1_helix PF18436.1 EGO53919.1 - 0.082 13.0 2.2 0.49 10.6 0.1 3.1 3 0 0 3 3 3 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 DUF4470 PF14737.6 EGO53920.1 - 9.2e-22 77.1 0.0 2.1e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EGO53920.1 - 2.2e-10 40.4 14.5 5.7e-10 39.1 14.5 1.8 1 0 0 1 1 1 1 MYND finger YL1 PF05764.13 EGO53920.1 - 0.0048 17.0 1.0 0.0048 17.0 1.0 2.8 3 0 0 3 3 3 1 YL1 nuclear protein DUF2052 PF09747.9 EGO53920.1 - 0.4 10.8 18.2 1.7 8.8 3.9 2.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) HET PF06985.11 EGO53921.1 - 1.1e-34 119.9 0.1 1.8e-34 119.2 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2272 PF10030.9 EGO53921.1 - 0.053 13.3 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) C1_4 PF07975.12 EGO53921.1 - 0.18 12.1 0.3 0.18 12.1 0.3 1.8 2 0 0 2 2 2 0 TFIIH C1-like domain DUF4470 PF14737.6 EGO53922.1 - 4.6e-15 55.6 0.5 5.2e-09 36.2 0.1 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4470) ER_lumen_recept PF00810.18 EGO53922.1 - 0.071 13.9 0.1 0.15 12.9 0.1 1.5 1 0 0 1 1 1 0 ER lumen protein retaining receptor T2SSB PF16537.5 EGO53922.1 - 0.2 11.3 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system protein B zf-MYND PF01753.18 EGO53923.1 - 0.0027 17.8 11.0 0.0067 16.5 11.0 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EGO53923.1 - 0.045 14.1 6.3 0.1 12.9 6.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding GMC_oxred_N PF00732.19 EGO53924.1 - 5.4e-57 193.4 0.0 1.5e-56 192.0 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGO53924.1 - 2.6e-06 26.8 0.1 0.0063 15.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EGO53924.1 - 3.7e-05 23.9 0.1 8.3e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_C PF05199.13 EGO53924.1 - 6.8e-05 23.4 0.1 0.00015 22.3 0.1 1.6 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EGO53924.1 - 7.2e-05 22.5 0.1 0.0039 16.8 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGO53924.1 - 0.00053 19.1 0.1 0.00081 18.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EGO53924.1 - 0.0013 18.0 0.0 0.0036 16.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO53924.1 - 0.0045 16.3 0.0 0.074 12.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO53924.1 - 0.034 13.4 0.1 0.092 12.0 0.0 1.6 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 EGO53924.1 - 0.056 12.1 0.0 0.093 11.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 EGO53924.1 - 0.13 11.0 0.0 0.45 9.3 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 EGO53925.1 - 8.3e-11 41.7 0.0 3.5e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO53925.1 - 0.00072 19.6 0.0 0.009 16.0 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EGO53925.1 - 0.00098 18.8 0.2 0.0027 17.3 0.1 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO53925.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGO53925.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Lactamase_B PF00753.27 EGO53926.1 - 9.2e-16 58.4 0.3 1.6e-15 57.6 0.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGO53926.1 - 0.0033 17.0 0.0 0.0076 15.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain F-box PF00646.33 EGO53927.1 - 4.8e-05 23.1 0.1 0.00013 21.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGO53927.1 - 0.0029 17.5 0.1 0.0062 16.4 0.1 1.5 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 EGO53927.1 - 0.004 17.0 0.1 0.004 17.0 0.1 1.9 2 0 0 2 2 2 1 F-box-like DZR PF12773.7 EGO53928.1 - 0.12 12.5 3.3 1.2 9.3 3.3 2.1 1 1 0 1 1 1 0 Double zinc ribbon Phage_holin_3_6 PF07332.11 EGO53929.1 - 0.089 12.8 3.8 0.34 11.0 0.0 2.7 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Methyltransf_23 PF13489.6 EGO53932.1 - 2.3e-19 69.9 0.0 3.3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO53932.1 - 4.4e-15 56.2 0.0 1.2e-14 54.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO53932.1 - 1.2e-10 42.0 0.0 4e-10 40.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO53932.1 - 2.2e-10 41.0 0.0 4.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO53932.1 - 2.8e-10 40.2 0.0 7.1e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO53932.1 - 6.7e-06 25.6 0.0 0.00012 21.4 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EGO53932.1 - 0.00053 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EGO53932.1 - 0.0019 17.7 0.0 0.0044 16.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGO53932.1 - 0.0039 16.6 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EGO53932.1 - 0.006 16.7 0.0 0.013 15.6 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EGO53932.1 - 0.0089 15.8 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 EGO53932.1 - 0.03 13.6 0.0 0.28 10.4 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase domain DOT1 PF08123.13 EGO53932.1 - 0.039 13.5 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Histone methylation protein DOT1 DUF938 PF06080.12 EGO53932.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CMAS PF02353.20 EGO53932.1 - 0.072 12.4 0.0 0.17 11.1 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase DREV PF05219.12 EGO53932.1 - 0.17 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase ADK PF00406.22 EGO53933.1 - 5.6e-26 91.4 0.0 6.4e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGO53933.1 - 2.3e-18 66.9 0.0 3e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO53933.1 - 1.2e-06 29.1 0.0 4e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO53933.1 - 0.0005 20.2 0.4 0.0053 16.9 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO53933.1 - 0.0023 18.3 0.0 0.0029 18.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain CoaE PF01121.20 EGO53933.1 - 0.006 16.3 0.3 1.6 8.3 0.0 2.1 2 0 0 2 2 2 2 Dephospho-CoA kinase Zeta_toxin PF06414.12 EGO53933.1 - 0.045 13.0 0.1 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 EGO53933.1 - 0.092 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGO53933.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 EGO53933.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 EGO53933.1 - 0.14 11.9 0.0 0.38 10.5 0.1 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EGO53933.1 - 0.16 12.5 0.0 0.29 11.7 0.0 1.5 2 0 0 2 2 2 0 ABC transporter Cerato-platanin PF07249.12 EGO53936.1 - 4.1e-05 23.7 0.3 4.1e-05 23.7 0.3 1.8 2 0 0 2 2 2 1 Cerato-platanin NUDIX PF00293.28 EGO53937.1 - 4.7e-18 65.5 0.0 6e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EGO53937.1 - 0.00029 20.8 0.1 0.00075 19.5 0.1 1.8 1 1 0 1 1 1 1 NUDIX domain Peptidase_M20 PF01546.28 EGO53938.1 - 2.9e-05 23.9 0.2 2.9e-05 23.9 0.2 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGO53938.1 - 0.0002 21.2 0.1 0.0005 20.0 0.1 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF1996 PF09362.10 EGO53939.1 - 8.3e-87 291.0 1.7 1.1e-86 290.7 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ank PF00023.30 EGO53940.1 - 1.7e-19 69.3 4.2 0.00022 21.5 0.1 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 EGO53940.1 - 2.5e-19 69.6 0.0 1.3e-06 28.8 0.0 4.6 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO53940.1 - 2.1e-16 60.1 0.3 0.006 17.1 0.0 5.5 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO53940.1 - 2.1e-16 58.3 0.5 0.093 13.3 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EGO53940.1 - 2.9e-12 46.6 0.5 0.031 14.6 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeats (many copies) FAD_binding_3 PF01494.19 EGO53943.1 - 1e-14 54.5 3.5 7.3e-08 32.0 0.2 3.4 3 1 0 3 3 3 2 FAD binding domain FAD_binding_2 PF00890.24 EGO53943.1 - 3.8e-09 36.1 0.2 3.1e-08 33.1 0.1 2.0 1 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO53943.1 - 7.1e-09 35.3 0.0 5.5e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO53943.1 - 3e-06 27.4 0.0 7.9e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGO53943.1 - 8.3e-06 25.1 0.1 0.0064 15.6 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EGO53943.1 - 1.3e-05 24.8 0.1 5.2e-05 22.8 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGO53943.1 - 1.6e-05 23.8 0.0 0.00096 17.9 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EGO53943.1 - 2e-05 24.4 0.7 0.004 16.8 0.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGO53943.1 - 0.00011 21.4 0.0 0.066 12.3 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EGO53943.1 - 0.00038 19.8 0.0 0.019 14.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGO53943.1 - 0.0038 16.5 0.0 0.0098 15.2 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EGO53943.1 - 0.021 15.4 0.0 0.7 10.5 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO53943.1 - 0.033 13.4 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 EGO53943.1 - 0.05 12.4 0.0 2 7.2 0.0 2.4 2 0 0 2 2 2 0 Tryptophan halogenase p450 PF00067.22 EGO53944.1 - 1.6e-49 168.9 0.0 2.3e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF5476 PF17570.2 EGO53944.1 - 0.21 12.0 0.9 0.47 10.9 0.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5476) DUF1772 PF08592.11 EGO53945.1 - 9.8e-26 90.7 1.6 1.5e-25 90.1 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) SnoaL PF07366.12 EGO53946.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EGO53946.1 - 0.014 16.0 0.0 0.032 14.8 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain NmrA PF05368.13 EGO53947.1 - 1.8e-31 109.5 0.0 2.6e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO53947.1 - 3.7e-11 43.3 0.0 4.8e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO53947.1 - 0.00013 21.5 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO53947.1 - 0.032 13.3 0.0 0.065 12.2 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGO53947.1 - 0.2 10.8 0.0 1.4 8.0 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein tRNA-synt_2 PF00152.20 EGO53955.1 - 2.2e-72 243.8 0.0 3.3e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 EGO53955.1 - 4.2e-22 78.5 0.0 6.6e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 EGO53955.1 - 3.2e-08 33.4 0.1 8.4e-08 32.1 0.1 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGO53955.1 - 0.0011 18.6 0.2 0.42 10.0 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF3492 PF11997.8 EGO53955.1 - 0.039 13.7 0.2 0.08 12.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Abhydrolase_3 PF07859.13 EGO53956.1 - 5.1e-46 157.2 0.0 6.4e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EGO53956.1 - 1.1e-05 24.6 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 EGO53956.1 - 0.0047 16.6 0.1 0.055 13.1 0.1 2.1 1 1 0 1 1 1 1 Putative esterase DUF2974 PF11187.8 EGO53956.1 - 0.054 13.1 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) GFO_IDH_MocA PF01408.22 EGO53957.1 - 1.6e-08 35.4 0.0 3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CRS1_YhbY PF01985.21 EGO53957.1 - 0.043 14.0 0.1 0.095 12.9 0.1 1.6 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain GFO_IDH_MocA_C PF02894.17 EGO53957.1 - 0.11 12.5 0.1 1.1 9.3 0.0 2.4 3 0 0 3 3 3 0 Oxidoreductase family, C-terminal alpha/beta domain PriC PF07445.12 EGO53958.1 - 0.0023 17.9 1.5 0.98 9.3 0.1 2.3 1 1 1 2 2 2 2 Primosomal replication protein priC DivIVA PF05103.13 EGO53958.1 - 0.003 17.7 0.9 0.0066 16.5 0.9 1.6 1 0 0 1 1 1 1 DivIVA protein DUF1664 PF07889.12 EGO53958.1 - 0.22 11.5 2.2 1.4 9.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Stn1 PF10451.9 EGO53959.1 - 1.4e-15 57.0 4.2 3.9e-09 35.9 0.4 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 EGO53959.1 - 1.7e-06 27.9 0.0 5.5e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain NINJA_B PF16136.5 EGO53959.1 - 0.12 12.7 11.4 0.24 11.8 11.4 1.6 1 0 0 1 1 1 0 Putative nuclear localisation signal DnaJ_CXXCXGXG PF00684.19 EGO53960.1 - 0.18 12.2 4.4 0.67 10.4 4.4 1.9 1 0 0 1 1 1 0 DnaJ central domain Glyco_hydro81C PF17652.1 EGO53961.1 - 5.5e-143 476.4 3.8 1.4e-140 468.5 4.3 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EGO53961.1 - 6.6e-98 327.8 0.0 9.4e-98 327.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Na_Ca_ex PF01699.24 EGO53962.1 - 1.1e-43 148.8 35.7 4.5e-22 78.6 15.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1129 PF06570.11 EGO53962.1 - 0.14 11.6 3.2 0.89 9.0 3.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) FUSC-like PF12805.7 EGO53962.1 - 0.21 10.6 0.1 0.21 10.6 0.1 1.9 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS DUF4658 PF15555.6 EGO53962.1 - 0.3 11.2 0.8 29 4.8 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4658) Patatin PF01734.22 EGO53963.1 - 2.8e-09 37.5 0.0 3.9e-05 23.9 0.0 2.8 2 1 0 2 2 2 2 Patatin-like phospholipase Ashwin PF15323.6 EGO53963.1 - 0.0043 17.1 5.0 0.0043 17.1 5.0 3.2 3 0 0 3 3 3 1 Developmental protein HeLo PF14479.6 EGO53964.1 - 1.7e-36 126.0 2.5 1.3e-34 119.9 2.5 2.3 1 1 0 1 1 1 1 Prion-inhibition and propagation FAD_binding_4 PF01565.23 EGO53965.1 - 4.2e-16 58.9 0.0 6.4e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Rcd1 PF04078.13 EGO53967.1 - 5.2e-126 419.2 5.9 6.5e-126 418.9 5.9 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like OSCP PF00213.18 EGO53967.1 - 0.18 11.9 2.5 1 9.5 0.0 2.6 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit DEAD PF00270.29 EGO53968.1 - 1.8e-37 128.8 0.1 3.5e-37 127.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO53968.1 - 1.5e-30 105.8 0.4 1.7e-29 102.4 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO53968.1 - 9.6e-05 22.5 0.0 9.6e-05 22.5 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Zip PF02535.22 EGO53968.1 - 0.0018 17.6 2.1 0.0018 17.6 2.1 2.4 3 0 0 3 3 3 1 ZIP Zinc transporter AP3D1 PF06375.11 EGO53968.1 - 0.011 15.9 2.3 0.011 15.9 2.3 4.4 3 2 2 5 5 5 0 AP-3 complex subunit delta-1 Presenilin PF01080.17 EGO53968.1 - 1.6 7.4 24.9 2.1 7.0 19.5 2.1 2 0 0 2 2 2 0 Presenilin SPATA3 PF15662.5 EGO53968.1 - 6.8 7.3 11.7 14 6.3 11.7 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family SID-1_RNA_chan PF13965.6 EGO53968.1 - 6.8 5.0 5.1 12 4.1 5.1 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.14 EGO53968.1 - 7.3 4.8 26.8 0.44 8.8 0.1 2.2 2 0 0 2 2 2 0 CDC45-like protein GREB1 PF15782.5 EGO53968.1 - 7.9 3.4 12.6 11 3.0 12.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RRM_1 PF00076.22 EGO53969.1 - 1.2e-23 82.7 0.1 1.1e-10 41.2 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO53969.1 - 0.0078 16.0 0.0 0.69 9.8 0.0 2.1 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 EGO53969.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Na_H_Exchanger PF00999.21 EGO53970.1 - 5.2e-59 200.0 42.9 7.2e-59 199.5 42.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_hydro_47 PF01532.20 EGO53971.1 - 5.7e-144 480.4 0.0 6.7e-144 480.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rad10 PF03834.14 EGO53972.1 - 9.4e-48 161.0 0.2 1.3e-47 160.5 0.2 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) PRCC PF10253.9 EGO53973.1 - 2.1 9.1 12.8 9.3 7.0 12.8 2.2 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MR_MLE_C PF13378.6 EGO53974.1 - 1.4e-58 198.0 0.0 2.5e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EGO53974.1 - 0.00027 21.1 0.0 0.0006 20.0 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 EGO53974.1 - 0.0009 18.5 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Inv-AAD PF18785.1 EGO53975.1 - 7.1e-64 213.5 0.4 8.2e-64 213.3 0.4 1.0 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EGO53975.1 - 4.6e-15 55.3 0.0 6e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGO53975.1 - 5.2e-05 23.0 0.0 6.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 EGO53975.1 - 0.00016 21.6 0.0 0.00036 20.5 0.0 1.5 1 1 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 EGO53975.1 - 0.035 14.2 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 DnaJ PF00226.31 EGO53976.1 - 5.4e-22 77.7 0.6 5.4e-22 77.7 0.6 2.0 2 0 0 2 2 2 1 DnaJ domain DUF493 PF04359.14 EGO53976.1 - 0.057 14.0 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF493) TPR_MalT PF17874.1 EGO53976.1 - 0.1 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 MalT-like TPR region Asp PF00026.23 EGO53977.1 - 7.4e-55 186.6 0.0 8.9e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO53977.1 - 1.6e-10 41.5 0.5 1.2e-08 35.4 0.5 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGO53977.1 - 0.17 11.7 0.0 1.8 8.3 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Pkinase PF00069.25 EGO53978.1 - 4.5e-47 160.6 0.0 6.2e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO53978.1 - 8.6e-25 87.5 0.0 1.3e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO53978.1 - 0.01 14.6 0.6 0.03 13.1 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EGO53978.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGO53978.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EGO53978.1 - 0.097 12.6 0.2 0.097 12.6 0.2 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-RING_2 PF13639.6 EGO53980.1 - 3.9e-10 39.9 8.7 6e-10 39.3 8.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGO53980.1 - 6e-07 29.6 8.4 2.2e-06 27.8 8.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGO53980.1 - 9.3e-06 25.6 2.2 1.7e-05 24.8 2.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EGO53980.1 - 0.00017 21.4 8.5 0.00038 20.2 8.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO53980.1 - 0.00051 19.8 6.7 0.0011 18.8 6.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO53980.1 - 0.0009 19.1 2.7 0.12 12.2 0.8 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGO53980.1 - 0.0024 17.9 3.6 0.0055 16.7 3.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGO53980.1 - 0.0026 17.6 6.4 0.0047 16.8 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO53980.1 - 0.092 12.7 6.1 0.23 11.4 6.1 1.7 1 1 0 1 1 1 0 zinc-RING finger domain RNF220 PF15926.5 EGO53980.1 - 0.14 11.8 6.2 1.3 8.6 6.2 2.1 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 Rad50_zn_hook PF04423.14 EGO53980.1 - 0.17 11.8 4.8 4.8 7.1 0.2 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif Zn-C2H2_12 PF18112.1 EGO53980.1 - 0.26 11.8 6.7 2.6 8.6 0.1 3.1 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_11 PF17123.5 EGO53980.1 - 0.34 10.7 9.0 0.14 11.9 5.8 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-Di19 PF05605.12 EGO53980.1 - 0.48 10.8 5.8 12 6.2 1.2 2.8 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.6 EGO53980.1 - 0.48 10.3 8.8 5.4 6.9 8.4 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 EGO53980.1 - 0.66 9.9 9.6 5.2 7.0 9.6 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_60s PF00428.19 EGO53980.1 - 1 10.0 6.4 2.4 8.8 6.4 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein YdjO PF14169.6 EGO53980.1 - 1.6 8.5 6.3 2 8.2 1.1 2.5 2 1 0 2 2 2 0 Cold-inducible protein YdjO Tmpp129 PF10272.9 EGO53980.1 - 1.8 7.8 5.7 3.2 6.9 5.7 1.4 1 1 0 1 1 1 0 Putative transmembrane protein precursor Abhydrolase_3 PF07859.13 EGO53981.1 - 5.4e-41 140.8 0.0 5.4e-31 108.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO53981.1 - 1.4e-14 53.7 0.0 4.9e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EGO53981.1 - 0.039 13.2 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 COesterase PF00135.28 EGO53981.1 - 0.053 12.4 0.0 0.74 8.6 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family DUF3089 PF11288.8 EGO53981.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3089) Utp14 PF04615.13 EGO53982.1 - 1.3e-197 658.9 64.4 1.3e-197 658.9 64.4 2.2 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.9 EGO53983.1 - 1.3e-17 63.7 0.5 1.5e-17 63.4 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Pkinase PF00069.25 EGO53985.1 - 1.2e-28 100.2 0.0 1.5e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO53985.1 - 7.8e-12 45.0 0.0 9.2e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO53985.1 - 9.2e-09 34.6 0.0 1.2e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGO53985.1 - 0.1 11.9 0.0 0.17 11.3 0.0 1.3 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGO53985.1 - 0.22 10.8 0.0 6.4 6.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like FAD_binding_3 PF01494.19 EGO53987.1 - 2.9e-17 62.9 0.3 1.7e-12 47.3 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EGO53987.1 - 4.5e-10 39.2 1.0 0.00016 21.0 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO53987.1 - 1.3e-07 31.6 0.5 2.1e-05 24.3 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO53987.1 - 1.1e-06 28.8 0.1 4.8e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGO53987.1 - 4.1e-06 26.1 0.1 9.2e-06 25.0 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EGO53987.1 - 9.2e-06 26.1 0.0 0.0037 17.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGO53987.1 - 0.00013 21.4 0.1 0.45 9.8 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EGO53987.1 - 0.00022 20.0 0.0 0.0018 17.1 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EGO53987.1 - 0.00068 19.1 0.7 0.0042 16.5 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EGO53987.1 - 0.0031 16.6 0.3 0.0063 15.6 0.3 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 EGO53987.1 - 0.0037 16.2 0.0 2.3 7.0 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 EGO53987.1 - 0.02 14.2 0.0 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO53987.1 - 0.026 14.5 0.1 4.2 7.3 0.0 2.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EGO53987.1 - 0.072 12.1 0.0 3.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EGO53987.1 - 0.15 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.22 EGO53988.1 - 1.2e-64 218.8 0.0 1e-63 215.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 TadE PF07811.12 EGO53988.1 - 0.63 10.4 2.4 1.5 9.1 2.4 1.7 1 0 0 1 1 1 0 TadE-like protein Sugar_tr PF00083.24 EGO53989.1 - 5.5e-72 243.1 21.4 6.7e-72 242.8 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO53989.1 - 3.7e-19 68.8 30.4 7.5e-19 67.9 29.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1129 PF06570.11 EGO53989.1 - 0.61 9.5 12.8 0.019 14.5 2.0 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1129) OATP PF03137.20 EGO53989.1 - 0.85 7.8 10.8 0.02 13.2 0.5 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Aldedh PF00171.22 EGO53990.1 - 2.7e-163 543.8 0.1 3.1e-163 543.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGO53990.1 - 0.0048 16.4 0.0 0.43 10.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) DUF1612 PF07756.12 EGO53990.1 - 0.0069 16.6 0.2 0.013 15.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1612) LuxC PF05893.14 EGO53990.1 - 0.13 11.2 0.2 0.43 9.6 0.2 1.7 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) RicinB_lectin_2 PF14200.6 EGO53993.1 - 7.7e-38 129.1 5.7 8e-17 61.7 0.6 2.9 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EGO53993.1 - 2.4e-06 27.8 0.0 5.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Trehalase PF01204.18 EGO53993.1 - 0.0013 17.6 0.1 0.002 17.0 0.1 1.2 1 0 0 1 1 1 1 Trehalase F5_F8_type_C PF00754.25 EGO53993.1 - 0.01 15.9 0.0 0.086 13.0 0.0 2.4 1 1 1 2 2 2 0 F5/8 type C domain DHC_N1 PF08385.12 EGO53995.1 - 0.012 14.3 0.3 0.016 13.9 0.3 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 EnY2 PF10163.9 EGO53995.1 - 0.07 13.5 0.0 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 Transcription factor e(y)2 YceG_bac PF14266.6 EGO53995.1 - 0.095 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative component of 'biosynthetic module' Trp_DMAT PF11991.8 EGO53997.1 - 2e-56 192.0 0.1 7.8e-44 150.6 0.1 2.2 1 1 1 2 2 2 2 Tryptophan dimethylallyltransferase Pyridox_ox_2 PF12900.7 EGO53997.1 - 1.5e-33 115.8 0.0 2.3e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HET PF06985.11 EGO53998.1 - 3.3e-31 108.6 0.1 6e-31 107.8 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_31 PF13847.6 EGO53999.1 - 2.6e-24 85.7 0.0 3.5e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO53999.1 - 6.3e-24 84.5 0.0 9.7e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO53999.1 - 1.5e-22 80.1 0.0 3e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO53999.1 - 5.3e-17 62.4 0.0 8.1e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO53999.1 - 4.6e-16 59.1 0.0 6.8e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO53999.1 - 8.3e-16 58.0 0.0 1.1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGO53999.1 - 3.8e-06 26.6 0.0 7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 EGO53999.1 - 4.2e-06 26.5 0.0 7.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.18 EGO53999.1 - 4.2e-06 26.4 0.0 0.057 12.9 0.0 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain PCMT PF01135.19 EGO53999.1 - 0.00025 20.9 0.0 0.00036 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.16 EGO53999.1 - 0.00078 18.1 0.0 0.0015 17.2 0.0 1.4 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.7 EGO53999.1 - 0.00087 19.3 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGO53999.1 - 0.0011 18.9 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 EGO53999.1 - 0.0016 18.2 0.0 0.0024 17.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 EGO53999.1 - 0.0034 16.8 0.0 0.0048 16.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 EGO53999.1 - 0.0041 16.3 0.0 0.008 15.3 0.0 1.4 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_4 PF02390.17 EGO53999.1 - 0.012 15.1 0.0 0.048 13.1 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase NodS PF05401.11 EGO53999.1 - 0.03 14.0 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) FtsJ PF01728.19 EGO53999.1 - 0.038 14.1 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 EGO53999.1 - 0.07 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 EGO53999.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CN_hydrolase PF00795.22 EGO54001.1 - 3.1e-42 144.7 0.0 3.7e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Spermine_synth PF01564.17 EGO54002.1 - 1.3e-08 34.5 0.0 2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 EGO54002.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO54002.1 - 0.0043 17.8 0.0 0.0093 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.21 EGO54002.1 - 0.046 13.0 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_30 PF05430.11 EGO54002.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase PEMT PF04191.13 EGO54003.1 - 2.1e-32 111.6 4.4 1.2e-31 109.3 3.8 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.16 EGO54003.1 - 0.037 14.0 0.8 0.09 12.8 0.1 1.9 2 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase DUF3275 PF11679.8 EGO54010.1 - 0.16 11.9 1.5 0.21 11.5 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DSPc PF00782.20 EGO54013.1 - 0.061 13.1 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF4417 PF14386.6 EGO54013.1 - 0.075 12.6 0.0 0.085 12.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4417) AC_N PF16214.5 EGO54020.1 - 0.4 9.8 1.2 0.61 9.2 1.2 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Ub-Mut7C PF14451.6 EGO54021.1 - 0.086 12.7 0.0 0.86 9.5 0.0 2.4 2 0 0 2 2 2 0 Mut7-C ubiquitin DUF1140 PF06600.11 EGO54022.1 - 0.0073 16.7 0.8 0.093 13.2 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1140) DNA_pol_phi PF04931.13 EGO54026.1 - 0.23 9.5 41.0 0.24 9.5 41.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi Mpp10 PF04006.12 EGO54026.1 - 0.36 9.2 34.2 0.35 9.3 34.2 1.0 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 EGO54026.1 - 0.78 9.1 33.7 0.82 9.0 33.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIP PF07454.11 EGO54026.1 - 0.91 8.9 17.8 0.84 9.0 17.8 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 EGO54026.1 - 1 9.5 16.4 1.2 9.2 16.4 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_Rpc4 PF05132.14 EGO54026.1 - 1 9.8 13.6 1 9.8 13.6 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 SDA1 PF05285.12 EGO54026.1 - 1.1 8.6 35.6 1.1 8.6 35.6 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EGO54026.1 - 1.4 7.0 36.6 1.4 7.0 36.6 1.0 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 EGO54026.1 - 2.3 8.5 19.8 2.4 8.5 19.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Merozoite_SPAM PF07133.11 EGO54026.1 - 3.1 7.8 53.8 2.9 7.9 53.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RNA_polI_A34 PF08208.11 EGO54026.1 - 3.3 7.7 24.0 3.2 7.8 24.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NPR3 PF03666.13 EGO54026.1 - 3.6 6.3 16.0 3.4 6.3 16.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.17 EGO54026.1 - 4.3 7.4 10.7 4.3 7.4 10.7 1.1 1 0 0 1 1 1 0 DDHD domain Eapp_C PF10238.9 EGO54026.1 - 5 7.2 14.5 6 6.9 14.5 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein Tim54 PF11711.8 EGO54026.1 - 6.1 5.5 22.7 6.3 5.5 22.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Afi1 PF07792.12 EGO54026.1 - 6.3 7.3 17.1 6.7 7.2 17.1 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CSRNP_N PF16019.5 EGO54026.1 - 6.6 6.6 12.4 6.9 6.5 12.4 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Sigma70_ner PF04546.13 EGO54026.1 - 7.1 6.5 29.5 8.4 6.2 29.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.10 EGO54026.1 - 7.1 5.8 33.3 7.3 5.8 33.3 1.0 1 0 0 1 1 1 0 BUD22 DUF4045 PF13254.6 EGO54026.1 - 8.8 5.9 14.4 8.1 6.0 14.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RR_TM4-6 PF06459.12 EGO54026.1 - 9.5 6.0 28.2 9.5 6.0 28.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NACHT_N PF17100.5 EGO54027.1 - 6.6e-81 271.4 1.6 7.6e-81 271.2 1.6 1.0 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase PA28_alpha PF02251.18 EGO54027.1 - 0.073 13.1 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit WD40 PF00400.32 EGO54028.1 - 1.5e-135 437.1 49.3 6.8e-13 48.9 0.9 11.8 11 1 1 12 12 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO54028.1 - 3.8e-48 161.7 0.0 0.00071 19.8 0.0 11.3 1 1 10 11 11 11 11 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EGO54028.1 - 1.7e-28 99.6 0.0 3e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 EGO54028.1 - 3.2e-23 82.2 13.9 0.7 8.8 0.0 10.7 1 1 6 9 9 9 8 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGO54028.1 - 2.5e-21 75.1 8.5 4.4 7.4 0.0 11.5 11 0 0 11 11 11 4 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EGO54028.1 - 6.6e-12 45.7 0.0 0.009 15.9 0.0 4.5 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGO54028.1 - 1.1e-10 41.4 0.0 0.33 10.2 0.0 6.5 3 2 5 8 8 8 4 WD40-like domain Gmad1 PF10647.9 EGO54028.1 - 3.2e-08 33.6 13.7 1.9 8.2 0.5 9.1 1 1 5 7 7 7 2 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.16 EGO54028.1 - 5.1e-06 25.3 0.0 0.82 8.1 0.0 3.8 1 1 2 4 4 4 2 Cytochrome D1 heme domain Nbas_N PF15492.6 EGO54028.1 - 1.8e-05 24.2 12.3 11 5.2 0.0 8.8 1 1 7 9 9 9 0 Neuroblastoma-amplified sequence, N terminal WD40_3 PF15911.5 EGO54028.1 - 5e-05 23.2 0.0 2.7e+02 1.7 0.0 8.0 10 0 0 10 10 10 0 WD domain, G-beta repeat SRP9-21 PF05486.12 EGO54028.1 - 0.00011 22.5 0.1 6.4e+02 0.8 0.0 8.1 10 0 0 10 10 9 0 Signal recognition particle 9 kDa protein (SRP9) AAA PF00004.29 EGO54028.1 - 0.0045 17.4 0.0 0.014 15.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ELM2 PF01448.24 EGO54028.1 - 0.022 15.5 0.0 9.6e+02 0.6 0.0 7.1 10 0 0 10 10 9 0 ELM2 domain AAA_19 PF13245.6 EGO54028.1 - 0.058 13.7 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGO54028.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NQRA PF05896.11 EGO54028.1 - 0.23 10.8 0.0 25 4.2 0.0 2.9 2 1 0 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Chorion_1 PF01723.16 EGO54028.1 - 0.34 10.9 7.1 19 5.2 0.1 5.3 1 1 7 8 8 8 0 Chorion protein TPR_10 PF13374.6 EGO54029.1 - 3.6e-16 58.5 0.1 1.9e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGO54029.1 - 9.6e-12 45.0 0.0 3.3e-07 30.5 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat Ank_4 PF13637.6 EGO54030.1 - 3.4e-20 72.1 0.0 4.5e-12 46.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO54030.1 - 1.2e-15 57.9 0.1 1.5e-15 57.5 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGO54030.1 - 1.3e-13 50.7 0.2 0.00057 20.2 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EGO54030.1 - 1.4e-10 41.2 0.0 3.8e-06 27.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO54030.1 - 4.1e-10 39.0 0.0 0.0062 16.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat VWA_3_C PF18571.1 EGO54030.1 - 0.015 15.1 0.2 3.9 7.4 0.0 3.1 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain zf-CHY PF05495.12 EGO54032.1 - 1.2e-11 44.9 12.4 1.2e-11 44.9 12.4 3.4 2 1 1 3 3 3 1 CHY zinc finger Mu-like_Com PF10122.9 EGO54032.1 - 0.033 13.6 0.1 0.17 11.3 0.1 2.3 1 0 0 1 1 1 0 Mu-like prophage protein Com zinc_ribbon_15 PF17032.5 EGO54032.1 - 0.33 11.7 20.8 16 6.3 0.2 3.6 3 0 0 3 3 3 0 zinc-ribbon family FUSC PF04632.12 EGO54032.1 - 0.65 8.5 3.2 0.98 7.9 3.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3295 PF11702.8 EGO54034.1 - 8.4e-162 540.0 24.2 1.6e-161 539.1 24.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 EGO54034.1 - 2.2e-12 46.6 2.9 4.2e-12 45.7 2.9 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Pyr_redox_2 PF07992.14 EGO54037.1 - 1.6e-42 145.8 0.1 2.6e-42 145.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 EGO54037.1 - 1.3e-16 60.5 0.1 3.7e-16 59.0 0.0 1.7 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Fer2_BFD PF04324.15 EGO54037.1 - 1.7e-14 53.9 2.1 1.3e-09 38.2 1.7 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Pyr_redox PF00070.27 EGO54037.1 - 1.1e-13 51.5 7.3 4.3e-13 49.6 2.8 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 EGO54037.1 - 9.5e-12 44.8 0.0 1.3e-05 25.0 0.0 3.1 3 0 0 3 3 3 2 Rieske-like [2Fe-2S] domain Rieske PF00355.26 EGO54037.1 - 1e-10 41.4 0.3 5.1e-06 26.3 0.0 3.4 4 0 0 4 4 4 2 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 EGO54037.1 - 9.8e-09 34.9 0.0 2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 EGO54037.1 - 0.0009 19.1 0.3 2.1 8.3 0.1 3.1 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 EGO54037.1 - 0.003 17.6 1.4 0.69 9.9 0.1 3.3 2 1 1 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGO54037.1 - 0.18 12.1 1.3 0.66 10.2 0.4 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO54037.1 - 0.19 11.3 1.7 1.9 8.0 1.6 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EGO54037.1 - 0.23 11.9 0.6 33 5.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.18 EGO54037.1 - 0.59 10.4 4.1 11 6.3 0.3 2.5 2 0 0 2 2 2 0 TrkA-N domain Ceramidase_alk PF04734.13 EGO54038.1 - 3.4e-220 732.0 0.0 4e-220 731.7 0.0 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EGO54038.1 - 2.7e-61 206.3 0.0 4.4e-61 205.6 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Dynamin_N PF00350.23 EGO54039.1 - 2.4e-11 44.0 2.2 5.3e-11 42.9 0.1 2.7 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EGO54039.1 - 4.8e-05 23.4 0.1 0.0013 18.8 0.1 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EGO54039.1 - 0.00041 20.9 2.0 0.0088 16.6 0.0 3.2 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.6 EGO54039.1 - 0.041 14.3 0.0 0.29 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain DUF2018 PF09442.10 EGO54039.1 - 0.13 13.2 1.8 0.53 11.3 1.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) RsgA_GTPase PF03193.16 EGO54039.1 - 0.14 12.1 0.1 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 EGO54039.1 - 4.5 6.5 9.0 3.1 7.0 0.4 3.8 3 1 1 4 4 4 0 Zeta toxin VHS PF00790.19 EGO54041.1 - 5.9e-26 91.0 0.0 3.6e-25 88.5 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 EGO54041.1 - 9.4e-07 29.1 1.1 2.3e-06 27.8 1.1 1.7 1 0 0 1 1 1 1 GAT domain Macoilin PF09726.9 EGO54041.1 - 2.1 6.8 12.7 2.6 6.5 12.7 1.1 1 0 0 1 1 1 0 Macoilin family Amidohydro_3 PF07969.11 EGO54042.1 - 8.5e-10 38.7 0.0 1.3e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.20 EGO54042.1 - 1.4e-09 37.7 0.6 4.1e-07 29.6 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Glyco_hydro_3 PF00933.21 EGO54043.1 - 2.5e-59 201.2 0.0 3.5e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 EGO54043.1 - 0.0026 18.0 0.0 0.0071 16.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 EGO54043.1 - 0.069 13.1 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Glucosamine_iso PF01182.20 EGO54044.1 - 1e-21 77.9 0.0 1.9e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_2 PF03727.16 EGO54045.1 - 5.8e-52 176.5 0.0 8e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EGO54045.1 - 1e-39 136.6 0.0 1.5e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase NDT80_PhoG PF05224.12 EGO54046.1 - 8.2e-43 146.8 0.0 1.2e-42 146.2 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF3498 PF12004.8 EGO54046.1 - 0.91 8.6 8.7 0.1 11.7 3.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3498) Piwi PF02171.17 EGO54047.1 - 1.2e-65 221.7 0.0 1.9e-65 221.1 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EGO54047.1 - 6.6e-11 43.0 0.2 1.2e-10 42.1 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EGO54047.1 - 5.8e-10 38.7 0.0 1.3e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EGO54047.1 - 8.3e-10 38.9 0.0 3.1e-09 37.0 0.0 2.1 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 EGO54047.1 - 1.9e-07 31.0 0.0 3.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 PAZ domain Ribosomal_L11_N PF03946.14 EGO54047.1 - 0.038 13.8 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain DUF2014 PF09427.10 EGO54048.1 - 3.6e-111 370.7 5.2 5e-111 370.3 5.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 EGO54048.1 - 1.1e-17 63.7 0.6 2.1e-16 59.6 0.9 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HET PF06985.11 EGO54050.1 - 3.6e-28 98.7 0.0 6.7e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Rubredoxin_2 PF18073.1 EGO54050.1 - 0.044 13.5 1.2 0.14 11.9 1.2 1.9 1 0 0 1 1 1 0 Rubredoxin metal binding domain DUF4716 PF15837.5 EGO54051.1 - 9.6 6.4 8.0 27 4.9 8.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4716) Cation_ATPase_C PF00689.21 EGO54052.1 - 5.6e-44 150.0 6.3 5.6e-44 150.0 6.3 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGO54052.1 - 8.2e-34 116.7 0.3 8.2e-34 116.7 0.3 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGO54052.1 - 3.3e-22 78.4 0.0 6.3e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGO54052.1 - 1e-20 74.9 0.4 3.7e-20 73.1 0.4 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGO54052.1 - 2.7e-07 30.1 0.0 3.9e-05 23.2 0.0 3.6 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGO54052.1 - 7e-05 22.7 1.0 0.00016 21.5 1.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGO54052.1 - 0.03 14.7 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 EGO54052.1 - 0.044 12.6 6.8 0.0097 14.8 2.3 2.1 3 0 0 3 3 3 0 Lipopolysaccharide export system permease LptF/LptG DUF2976 PF11190.8 EGO54052.1 - 0.087 12.6 8.2 0.15 11.9 0.7 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) zf-primase PF09329.11 EGO54053.1 - 5.9e-19 67.6 0.8 1e-18 66.8 0.8 1.4 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.25 EGO54053.1 - 0.003 17.5 0.0 0.0096 15.9 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain BNIP2 PF12496.8 EGO54053.1 - 0.0068 16.8 0.8 0.027 14.9 0.8 2.0 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 ANAPC15 PF15243.6 EGO54053.1 - 0.24 11.8 4.9 0.77 10.2 0.3 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 RNase_H2-Ydr279 PF09468.10 EGO54055.1 - 6e-45 153.3 0.5 2.3e-44 151.4 0.0 2.2 2 2 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EGO54055.1 - 1.2e-23 83.1 0.1 4.9e-23 81.2 0.1 2.1 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain DASH_Duo1 PF08651.10 EGO54056.1 - 1.5e-31 107.9 0.2 2.3e-31 107.4 0.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 Peptidase_S30 PF01577.16 EGO54056.1 - 0.25 10.9 4.6 0.29 10.7 0.2 2.1 2 0 0 2 2 2 0 Potyvirus P1 protease Trs65 PF12735.7 EGO54056.1 - 0.6 9.5 5.7 1.1 8.6 5.7 1.3 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 RNA_pol_Rpc4 PF05132.14 EGO54056.1 - 0.98 9.8 9.4 0.51 10.8 2.1 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 BRF1 PF07741.13 EGO54056.1 - 1 9.8 13.4 4.5 7.7 3.2 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF1682 PF07946.14 EGO54056.1 - 1.1 8.5 5.2 1.6 7.9 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DASH_Dad2 PF08654.10 EGO54056.1 - 4.4 7.8 8.8 0.17 12.3 2.2 2.0 2 1 0 2 2 2 0 DASH complex subunit Dad2 Tom22 PF04281.13 EGO54056.1 - 4.8 7.0 7.3 1.1 9.1 0.3 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 DUF3439 PF11921.8 EGO54057.1 - 0.0039 17.1 5.0 0.0099 15.8 5.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) SSP160 PF06933.11 EGO54057.1 - 5.1 5.2 11.6 9.4 4.3 11.6 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TTL PF03133.15 EGO54059.1 - 1.4e-52 178.7 0.0 2.2e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 EGO54059.1 - 3.5e-49 167.2 0.0 5.3e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE Glyco_trans_4_4 PF13579.6 EGO54059.1 - 0.031 14.7 0.1 0.05 14.1 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EGO54059.1 - 0.085 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 RXT2_N PF08595.11 EGO54059.1 - 0.22 11.5 4.2 0.48 10.4 4.2 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 EGO54059.1 - 0.41 8.9 10.4 0.65 8.2 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 EGO54059.1 - 0.88 8.8 14.6 1.5 8.1 14.6 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EGO54059.1 - 2.5 7.5 15.5 3.7 6.9 15.5 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EGO54059.1 - 6 4.8 23.7 9.5 4.2 23.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 EGO54059.1 - 7.4 6.2 25.1 0.25 11.0 19.1 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.11 EGO54059.1 - 7.6 4.5 7.9 15 3.5 7.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PPP4R2 PF09184.11 EGO54059.1 - 8 6.0 10.7 14 5.2 10.7 1.3 1 0 0 1 1 1 0 PPP4R2 DHDPS PF00701.22 EGO54060.1 - 3.7e-13 48.8 0.0 5.2e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF3767 PF12597.8 EGO54060.1 - 0.2 11.5 0.0 23 4.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) DUF1604 PF07713.13 EGO54062.1 - 2.9e-42 142.4 3.7 6.5e-42 141.3 0.9 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EGO54062.1 - 1.9e-06 27.6 2.2 1.9e-06 27.6 2.2 3.0 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 EGO54062.1 - 0.0027 17.8 1.4 0.019 15.0 0.1 3.1 2 1 0 2 2 2 1 G-patch domain PYNP_C PF07831.13 EGO54062.1 - 0.21 11.3 0.8 0.66 9.7 0.8 1.8 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain Pkinase PF00069.25 EGO54064.1 - 1.5e-64 218.0 0.0 2.1e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO54064.1 - 5.3e-37 127.5 0.0 8e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EGO54064.1 - 1.4e-18 66.4 0.1 2.4e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 EGO54064.1 - 1.3e-06 27.9 0.2 2.8e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGO54064.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGO54064.1 - 0.00041 19.4 0.0 0.00073 18.6 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGO54064.1 - 0.00052 20.0 1.1 0.0029 17.5 1.1 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.11 EGO54064.1 - 0.037 13.6 0.1 0.06 13.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 EGO54064.1 - 0.051 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family BAF1_ABF1 PF04684.13 EGO54064.1 - 0.77 8.7 12.8 0.16 11.0 5.8 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Dicty_REP PF05086.12 EGO54064.1 - 7.4 4.4 11.4 0.24 9.4 4.0 1.9 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein HET PF06985.11 EGO54065.1 - 5.4e-28 98.2 0.3 8.9e-28 97.5 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Dna2 PF08696.11 EGO54066.1 - 3.3e-73 245.9 0.3 1.1e-72 244.1 0.0 2.0 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.6 EGO54066.1 - 5.1e-37 127.4 0.0 9.1e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 EGO54066.1 - 1.5e-08 34.9 0.1 7.8e-08 32.6 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF83 Csa1 PF06023.12 EGO54066.1 - 0.12 11.7 0.0 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated exonuclease Csa1 Gryzun PF07919.12 EGO54067.1 - 2.2e-176 588.2 0.4 2.1e-162 542.0 0.0 2.1 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 EGO54067.1 - 2.9e-99 331.9 2.2 4e-94 315.0 3.3 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Kelch_5 PF13854.6 EGO54068.1 - 1.3e-07 31.5 1.8 4.3e-06 26.6 0.1 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.6 EGO54068.1 - 0.045 14.1 3.5 18 5.8 0.1 4.8 6 0 0 6 6 6 0 Kelch motif CBM_10 PF02013.16 EGO54068.1 - 0.1 13.1 0.8 0.29 11.6 0.8 1.7 1 0 0 1 1 1 0 Cellulose or protein binding domain Kelch_4 PF13418.6 EGO54068.1 - 0.21 11.6 10.4 2.4 8.2 0.0 5.3 7 0 0 7 7 7 0 Galactose oxidase, central domain Kelch_1 PF01344.25 EGO54068.1 - 0.55 9.9 4.4 7.2 6.3 0.1 4.1 4 0 0 4 4 4 0 Kelch motif ESSS PF10183.9 EGO54070.1 - 4.1e-15 55.9 0.1 5.7e-15 55.4 0.1 1.3 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PIP49_C PF12260.8 EGO54070.1 - 0.02 14.5 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Aminotran_4 PF01063.19 EGO54071.1 - 2e-35 122.6 0.0 2.6e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV RNA_pol_I_A49 PF06870.12 EGO54071.1 - 0.2 10.5 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor Pkinase PF00069.25 EGO54072.1 - 5.2e-17 62.1 0.0 1.9e-16 60.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO54072.1 - 9.3e-09 34.9 0.0 7e-08 32.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase DCB PF16213.5 EGO54072.1 - 0.0027 17.4 2.4 0.013 15.2 0.3 2.6 2 1 1 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Spt20 PF12090.8 EGO54072.1 - 1.6 8.3 10.5 3.6 7.1 10.5 1.6 1 0 0 1 1 1 0 Spt20 family KRTAP PF11759.8 EGO54072.1 - 2.3 8.8 9.9 0.12 13.0 3.8 2.0 2 0 0 2 2 2 0 Keratin-associated matrix Aim21 PF11489.8 EGO54073.1 - 3.7e-186 621.2 117.7 3.7e-186 621.2 117.7 3.2 1 1 1 2 2 2 1 Altered inheritance of mitochondria protein 21 NTF2 PF02136.20 EGO54074.1 - 1.7e-31 109.3 0.0 1.9e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Cg6151-P PF10233.9 EGO54075.1 - 5.9e-42 142.5 12.0 7.1e-42 142.3 12.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 EGO54075.1 - 0.0019 17.9 5.5 0.0028 17.4 5.5 1.2 1 0 0 1 1 1 1 Transmembrane protein family 72 DUF1430 PF07242.11 EGO54075.1 - 0.59 10.4 6.8 0.22 11.8 3.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) COPI_assoc PF08507.10 EGO54075.1 - 1.6 8.8 12.7 3.4 7.7 12.6 1.5 1 1 0 1 1 1 0 COPI associated protein Cwf_Cwc_15 PF04889.12 EGO54076.1 - 0.46 10.2 14.1 0.39 10.4 5.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Seipin PF06775.14 EGO54077.1 - 1.9e-56 191.3 0.1 2.5e-56 190.9 0.1 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) SH3_1 PF00018.28 EGO54078.1 - 9e-13 47.6 0.0 1.9e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGO54078.1 - 1.9e-11 43.6 0.5 9.9e-11 41.3 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EGO54078.1 - 2e-11 43.4 0.0 2.2e-10 40.0 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain FCH PF00611.23 EGO54078.1 - 2.2e-11 43.9 1.3 2.2e-11 43.9 1.3 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain UPF0029 PF01205.19 EGO54079.1 - 1.8e-26 92.5 0.0 3.7e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Gp5_OB PF06714.11 EGO54079.1 - 0.07 13.4 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Gp5 N-terminal OB domain Methyltransf_23 PF13489.6 EGO54080.1 - 1.6e-19 70.4 0.0 1.8e-18 66.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO54080.1 - 6.3e-06 26.8 0.0 0.44 11.3 0.0 3.6 2 2 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 EGO54080.1 - 6e-05 23.7 0.0 0.0039 17.9 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO54080.1 - 0.00011 22.7 0.0 0.7 10.6 0.0 3.4 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 EGO54080.1 - 0.00061 19.6 0.0 0.21 11.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 EGO54080.1 - 0.0008 18.8 0.0 0.077 12.3 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family LYRIC PF15686.5 EGO54083.1 - 0.025 14.1 1.5 0.03 13.9 1.5 1.0 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family RPN2_C PF18004.1 EGO54083.1 - 0.026 14.5 0.3 0.034 14.1 0.3 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Sensor PF13796.6 EGO54083.1 - 0.13 12.3 1.1 0.17 11.9 1.1 1.2 1 0 0 1 1 1 0 Putative sensor Not1 PF04054.15 EGO54084.1 - 4.2e-122 407.6 0.0 1e-121 406.4 0.0 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EGO54084.1 - 1.7e-91 305.6 4.1 3.1e-91 304.8 4.1 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 EGO54084.1 - 7.3e-48 162.2 3.3 2e-47 160.8 3.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EGO54084.1 - 6.9e-41 139.5 0.0 2e-40 138.0 0.0 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EGO54084.1 - 1.3e-35 122.7 1.7 3.7e-35 121.2 0.1 2.6 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat DUF2624 PF11116.8 EGO54084.1 - 0.19 12.6 3.0 0.24 12.3 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2624) CorA PF01544.18 EGO54085.1 - 1.3e-09 37.9 7.6 3.6e-08 33.1 6.7 2.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF676 PF05057.14 EGO54085.1 - 5.2e-07 29.4 0.0 1.5e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AltA1 PF16541.5 EGO54085.1 - 0.0039 18.0 0.2 0.0079 17.1 0.2 1.4 1 0 0 1 1 1 1 Alternaria alternata allergen 1 Hydrolase_4 PF12146.8 EGO54085.1 - 0.0065 15.8 0.0 0.019 14.3 0.0 1.7 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ni_hydr_CYTB PF01292.20 EGO54085.1 - 0.03 13.9 0.8 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 Sacchrp_dh_NADP PF03435.18 EGO54085.1 - 0.12 12.6 0.3 0.29 11.4 0.3 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ETF_QO PF05187.13 EGO54086.1 - 5.5e-49 164.6 1.5 8.9e-49 164.0 1.5 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 EGO54086.1 - 2.1e-07 31.1 0.0 6.6e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO54086.1 - 2.5e-07 30.6 1.0 0.00021 21.0 0.8 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO54086.1 - 8.5e-06 25.2 0.0 0.00014 21.2 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO54086.1 - 6.7e-05 22.4 0.0 0.00014 21.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO54086.1 - 0.00018 20.7 0.7 0.004 16.3 0.9 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EGO54086.1 - 0.00076 20.0 0.2 1.8 9.2 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO54086.1 - 0.0008 18.2 0.3 0.0013 17.6 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 EGO54086.1 - 0.00097 18.1 0.1 0.091 11.6 0.1 2.4 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.19 EGO54086.1 - 0.0013 18.0 0.2 0.0026 17.1 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGO54086.1 - 0.0014 17.9 0.0 0.0098 15.2 0.1 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 EGO54086.1 - 0.0036 17.3 0.1 0.0091 16.0 0.1 1.6 2 0 0 2 2 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EGO54086.1 - 0.0051 16.1 0.4 0.009 15.3 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 EGO54086.1 - 0.0083 16.7 1.4 0.023 15.3 1.4 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 EGO54086.1 - 0.097 11.7 0.2 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_9 PF13187.6 EGO54086.1 - 0.13 12.5 0.8 0.26 11.5 0.8 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.22 EGO54086.1 - 0.14 11.2 0.4 0.23 10.5 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_2 PF12797.7 EGO54086.1 - 0.16 12.1 0.7 0.45 10.7 0.7 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain TBP PF00352.21 EGO54087.1 - 8.6e-68 224.3 0.1 7.2e-33 112.4 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EGO54087.1 - 0.00011 22.2 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EGO54087.1 - 0.13 12.1 0.1 0.69 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) DAO PF01266.24 EGO54088.1 - 4.5e-44 151.5 0.3 5.3e-44 151.2 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGO54088.1 - 2e-06 27.9 0.1 0.041 13.9 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGO54088.1 - 3.9e-05 23.8 0.1 0.00016 21.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO54088.1 - 0.00033 20.0 0.0 0.79 8.9 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 EGO54088.1 - 0.0033 17.7 0.0 0.0056 16.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GIDA PF01134.22 EGO54088.1 - 0.005 16.0 0.0 0.02 14.0 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 EGO54088.1 - 0.0071 15.2 0.0 1.3 7.7 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Glu_dehyd_C PF16912.5 EGO54088.1 - 0.034 13.6 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus CooC_C PF15976.5 EGO54088.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 CS1-pili formation C-terminal Surp PF01805.20 EGO54089.1 - 5.2e-11 42.4 0.0 1.4e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 Surp module Copper-fist PF00649.18 EGO54090.1 - 7.2e-18 63.8 1.3 1.7e-17 62.6 1.3 1.7 1 0 0 1 1 1 1 Copper fist DNA binding domain Methyltransf_16 PF10294.9 EGO54092.1 - 1.5e-11 44.4 0.0 2.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EGO54092.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 EGO54092.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G SARAF PF06682.12 EGO54094.1 - 0.063 12.9 2.2 0.16 11.6 2.2 1.7 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Connexin PF00029.19 EGO54094.1 - 0.19 11.5 0.1 0.65 9.7 0.1 1.8 1 1 0 1 1 1 0 Connexin DUF3915 PF13054.6 EGO54094.1 - 0.35 10.9 1.8 0.65 10.0 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) GRA6 PF05084.13 EGO54094.1 - 0.61 10.0 21.9 0.28 11.1 0.1 2.2 1 1 1 2 2 2 0 Granule antigen protein (GRA6) DUF4519 PF15012.6 EGO54094.1 - 0.84 9.9 2.7 2.1 8.6 2.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) OCD_Mu_crystall PF02423.15 EGO54095.1 - 9.6e-08 31.3 0.5 0.0042 16.1 0.0 2.7 3 0 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family CDC45 PF02724.14 EGO54095.1 - 0.25 9.6 5.4 0.37 9.0 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EGO54095.1 - 0.79 8.4 2.2 1.2 7.8 2.2 1.2 1 0 0 1 1 1 0 Presenilin Pro_CA PF00484.19 EGO54096.1 - 2.3e-46 157.9 0.2 2.8e-46 157.6 0.2 1.1 1 0 0 1 1 1 1 Carbonic anhydrase PAF-AH_p_II PF03403.13 EGO54096.1 - 0.11 10.9 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Ribosomal_L7Ae PF01248.26 EGO54097.1 - 2.6e-21 75.2 1.0 2.6e-21 75.2 1.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 EGO54097.1 - 0.037 13.0 0.2 0.047 12.7 0.2 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) zn-ribbon_14 PF16503.5 EGO54098.1 - 1.8e-18 65.7 5.5 1.8e-18 65.7 5.5 3.6 3 0 0 3 3 3 1 Zinc-ribbon ATP_bind_3 PF01171.20 EGO54098.1 - 1e-17 64.5 0.0 1.6e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 EGO54098.1 - 0.0049 16.4 1.3 0.0049 16.4 1.3 3.7 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.16 EGO54098.1 - 0.027 13.3 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase MWFE PF15879.5 EGO54099.1 - 1.2e-30 105.4 0.1 1.6e-30 105.0 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit MOZ_SAS PF01853.18 EGO54100.1 - 3.4e-77 258.2 0.1 4.8e-77 257.7 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EGO54100.1 - 7.3e-21 73.5 3.4 1.5e-20 72.5 3.4 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EGO54100.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ENTH PF01417.20 EGO54101.1 - 2.5e-48 163.3 0.0 3.7e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 EGO54101.1 - 0.00063 20.1 47.5 0.00063 20.1 47.5 6.4 2 1 2 4 4 4 1 Domain of unknown function (DUF1720) UIM PF02809.20 EGO54101.1 - 0.0065 16.3 5.9 0.03 14.2 0.3 2.9 2 0 0 2 2 2 1 Ubiquitin interaction motif ANTH PF07651.16 EGO54101.1 - 0.034 13.1 0.0 0.067 12.2 0.0 1.5 1 0 0 1 1 1 0 ANTH domain DUF4264 PF14084.6 EGO54101.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Nup96 PF12110.8 EGO54102.1 - 5.9e-53 179.9 0.2 5.8e-51 173.3 0.2 2.2 1 1 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EGO54102.1 - 1.1e-44 152.2 0.0 1.6e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EGO54102.1 - 8.4e-16 58.6 100.5 4e-10 40.4 30.5 10.9 3 2 5 8 8 8 3 Nucleoporin FG repeat region F-box-like PF12937.7 EGO54103.1 - 3.4e-09 36.4 0.3 3.4e-09 36.4 0.3 2.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EGO54103.1 - 3.2e-06 26.9 0.2 6.3e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 F-box domain SNF2_N PF00176.23 EGO54104.1 - 8.2e-67 225.4 0.6 6.3e-62 209.3 0.1 3.1 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO54104.1 - 4.4e-15 56.0 0.0 1.1e-14 54.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO54104.1 - 4.9e-06 26.7 0.0 1.6e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit E6 PF00518.17 EGO54104.1 - 0.28 11.7 2.6 4.8 7.7 1.9 2.5 2 0 0 2 2 2 0 Early Protein (E6) BUD22 PF09073.10 EGO54104.1 - 2.3 7.5 37.4 0.47 9.7 30.8 2.6 2 0 0 2 2 2 0 BUD22 TRAUB PF08164.12 EGO54105.1 - 1.3e-30 105.7 0.1 6.3e-30 103.5 0.1 2.3 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EGO54105.1 - 1.9e-26 93.4 0.5 1.9e-26 93.4 0.5 3.5 4 2 0 4 4 4 1 Apoptosis antagonizing transcription factor Ran-binding PF05508.11 EGO54106.1 - 3.8e-112 374.3 0.0 4.9e-112 374.0 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.27 EGO54107.1 - 1.3e-41 142.3 0.0 2e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGO54107.1 - 4.6e-29 101.0 0.0 1.4e-28 99.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGO54107.1 - 6.6e-08 32.8 0.3 1.7e-07 31.5 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGO54107.1 - 0.00088 19.3 0.1 0.0046 17.0 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Mitofilin PF09731.9 EGO54107.1 - 1 8.1 14.1 1.5 7.6 14.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein adh_short_C2 PF13561.6 EGO54108.1 - 9.1e-31 107.2 0.0 1.1e-19 70.9 0.1 3.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO54108.1 - 3.9e-29 101.5 0.0 5.9e-16 58.5 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EGO54108.1 - 3e-10 40.3 0.1 8.1e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EGO54108.1 - 0.058 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UCH_1 PF13423.6 EGO54109.1 - 5.2e-85 285.8 0.3 7.6e-85 285.3 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Mito_carr PF00153.27 EGO54109.1 - 1.4e-48 162.7 6.2 2.5e-17 62.6 0.1 4.3 4 0 0 4 4 4 3 Mitochondrial carrier protein RNase_T PF00929.24 EGO54109.1 - 1.4e-20 74.5 0.0 3.4e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 EGO54109.1 - 0.00026 20.6 0.0 0.00079 19.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Methyltransf_FA PF12248.8 EGO54109.1 - 0.16 12.3 0.1 0.93 9.9 0.0 2.2 2 0 0 2 2 2 0 Farnesoic acid 0-methyl transferase Tudor_3 PF18115.1 EGO54111.1 - 3.5e-08 33.2 0.0 5.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 EGO54111.1 - 3.3e-05 23.6 0.0 6.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain DUF1325 PF07039.11 EGO54111.1 - 0.002 18.2 0.3 0.0043 17.1 0.3 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.6 EGO54111.1 - 0.0075 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Syntaxin-6_N PF09177.11 EGO54111.1 - 0.083 13.4 0.3 0.15 12.7 0.3 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Fis1_TPR_C PF14853.6 EGO54111.1 - 0.19 11.8 0.3 0.34 11.0 0.3 1.3 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat SOG2 PF10428.9 EGO54111.1 - 0.55 9.4 6.0 0.65 9.1 6.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein TCO89 PF10452.9 EGO54112.1 - 4.4e-06 26.0 1.7 4.4e-06 26.0 1.7 3.7 2 2 0 2 2 2 1 TORC1 subunit TCO89 Lin-8 PF03353.15 EGO54112.1 - 0.62 9.6 11.4 1.4 8.4 11.4 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Thiolase_N PF00108.23 EGO54113.1 - 6.9e-75 251.8 2.6 9.9e-75 251.2 2.6 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGO54113.1 - 2.4e-44 149.9 0.1 4.7e-44 149.0 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGO54113.1 - 0.0068 16.0 3.3 0.011 15.3 0.7 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 EGO54113.1 - 0.046 13.9 0.0 0.19 11.9 0.0 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EGO54113.1 - 0.24 11.3 1.9 16 5.4 0.1 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FBPase PF00316.20 EGO54114.1 - 1.1e-71 240.2 0.3 1.5e-71 239.8 0.3 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NdhM PF10664.9 EGO54114.1 - 0.046 14.0 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M Inositol_P PF00459.25 EGO54114.1 - 0.089 12.3 0.0 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 Inositol monophosphatase family Glyco_hydro_92 PF07971.12 EGO54115.1 - 4e-118 395.3 3.1 1.5e-115 386.8 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EGO54115.1 - 1.4e-65 221.5 0.1 2.2e-65 220.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain RRM_1 PF00076.22 EGO54116.1 - 6.6e-82 269.3 6.5 1.2e-21 76.3 0.5 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EGO54116.1 - 2.6e-26 91.6 1.1 1.2e-25 89.4 1.3 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EGO54116.1 - 8.2e-11 41.6 0.0 0.0014 18.2 0.0 5.2 2 1 3 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO54116.1 - 4.1e-07 29.8 0.0 0.0011 18.8 0.0 3.6 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EGO54116.1 - 6.7e-06 26.1 0.3 1.8 8.7 0.0 5.4 4 1 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EGO54116.1 - 0.00012 22.0 1.7 6 6.9 0.0 4.5 4 1 0 4 4 4 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.8 EGO54116.1 - 0.00054 20.0 0.1 15 5.8 0.0 3.8 4 0 0 4 4 4 0 Cobalamin biosynthesis central region YflT PF11181.8 EGO54116.1 - 0.005 17.3 6.9 0.024 15.2 0.3 3.3 3 0 0 3 3 3 1 Heat induced stress protein YflT Nefa_Nip30_N PF10187.9 EGO54116.1 - 0.041 14.2 0.1 0.041 14.2 0.1 4.1 5 0 0 5 5 4 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Limkain-b1 PF11608.8 EGO54116.1 - 0.078 13.1 0.9 22 5.2 0.1 3.3 3 0 0 3 3 3 0 Limkain b1 OB_RNB PF08206.11 EGO54116.1 - 0.087 12.5 1.8 8 6.2 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain PhetRS_B1 PF18262.1 EGO54116.1 - 0.12 12.6 2.2 5.6 7.3 0.0 3.3 3 1 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain DHHA1 PF02272.19 EGO54116.1 - 0.55 10.7 8.3 3.2 8.2 0.2 3.3 3 0 0 3 3 3 0 DHHA1 domain DUF3408 PF11888.8 EGO54116.1 - 5.9 7.0 12.2 0.33 11.1 3.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) HECT PF00632.25 EGO54117.1 - 7e-81 272.1 0.0 1.2e-80 271.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4777 PF16007.5 EGO54117.1 - 0.031 14.5 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) Chal_sti_synt_C PF02797.15 EGO54118.1 - 1.2e-20 74.0 0.0 2.6e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 EGO54118.1 - 1.3e-20 73.8 0.1 1.9e-20 73.3 0.1 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.12 EGO54118.1 - 0.00087 18.7 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 EGO54118.1 - 0.0024 18.0 0.0 0.0073 16.5 0.0 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EGO54118.1 - 0.0068 16.2 0.2 0.019 14.8 0.2 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PEX11 PF05648.14 EGO54119.1 - 6e-73 245.0 0.6 6.8e-73 244.8 0.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) NMO PF03060.15 EGO54120.1 - 1.2e-55 189.2 0.5 1.3e-54 185.8 0.5 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGO54120.1 - 4.1e-14 52.3 0.0 5.5e-12 45.3 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGO54120.1 - 0.002 17.2 0.2 0.0034 16.5 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 EGO54120.1 - 0.053 13.0 0.1 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein Glu_synthase PF01645.17 EGO54120.1 - 0.17 11.0 1.0 0.64 9.1 1.0 1.9 1 1 0 1 1 1 0 Conserved region in glutamate synthase dsrm PF00035.26 EGO54122.1 - 1.5e-05 25.6 0.0 2.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EGO54122.1 - 0.0023 18.2 0.9 0.043 14.1 0.9 2.1 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 Ribosomal_S7 PF00177.21 EGO54123.1 - 3.2e-27 95.0 0.0 2.3e-26 92.2 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e Usp PF00582.26 EGO54124.1 - 1.2e-23 84.2 7.9 7.4e-16 58.9 0.2 3.7 5 0 0 5 5 5 2 Universal stress protein family Sugar_tr PF00083.24 EGO54126.1 - 8.4e-35 120.5 27.4 1.7e-19 70.0 10.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGO54126.1 - 1.3e-17 63.8 44.8 7.3e-11 41.6 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ac76 PF05814.11 EGO54126.1 - 0.19 11.8 0.7 0.62 10.1 0.2 2.1 2 0 0 2 2 2 0 Orf76 (Ac76) PTPA PF03095.15 EGO54127.1 - 4.5e-118 394.1 0.0 8e-118 393.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Pkinase PF00069.25 EGO54129.1 - 0.00073 19.0 0.0 0.51 9.6 0.0 3.3 4 0 0 4 4 4 2 Protein kinase domain Ribosomal_60s PF00428.19 EGO54129.1 - 0.037 14.6 0.4 0.037 14.6 0.4 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein AT_hook PF02178.19 EGO54130.1 - 0.11 12.4 6.1 0.44 10.6 6.1 2.1 1 0 0 1 1 1 0 AT hook motif DUF21 PF01595.20 EGO54131.1 - 3.5e-33 114.8 0.0 5.9e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EGO54131.1 - 8.2e-06 26.2 0.4 0.0074 16.7 0.0 3.9 5 0 0 5 5 5 2 CBS domain Glyoxalase PF00903.25 EGO54132.1 - 3e-38 130.9 0.1 7.3e-18 65.0 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGO54132.1 - 4.3e-14 52.7 0.0 8.7e-06 26.0 0.0 3.7 2 2 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EGO54132.1 - 7.2e-06 26.7 0.0 0.12 13.1 0.0 2.8 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EGO54132.1 - 2.4e-05 24.2 0.7 0.026 14.4 0.1 3.9 3 1 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EGO54132.1 - 0.00023 21.3 0.0 1.7 8.7 0.0 3.0 1 1 3 4 4 4 4 Glyoxalase-like domain CppA_N PF14506.6 EGO54132.1 - 0.0051 16.9 0.1 0.14 12.2 0.0 2.3 2 0 0 2 2 2 1 CppA N-terminal MoaF PF10703.9 EGO54132.1 - 0.082 12.8 0.0 3.8 7.5 0.0 2.5 2 1 0 2 2 2 0 MoaF N-terminal domain Pfk_N PF18468.1 EGO54132.1 - 0.17 12.3 0.3 25 5.4 0.0 2.5 2 0 0 2 2 2 0 Phosphofructokinase N-terminal domain yeast DUF3565 PF12088.8 EGO54133.1 - 0.047 13.7 0.3 0.27 11.2 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3565) COX15-CtaA PF02628.15 EGO54134.1 - 1.2e-110 369.6 8.4 1.6e-110 369.2 8.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Cation_efflux PF01545.21 EGO54135.1 - 9.3e-13 48.4 16.0 1.2e-07 31.7 4.0 2.3 1 1 1 2 2 2 2 Cation efflux family ZT_dimer PF16916.5 EGO54135.1 - 2.9e-05 24.1 0.6 5.3e-05 23.3 0.6 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Zip PF02535.22 EGO54136.1 - 2.5e-56 191.3 0.2 3.1e-56 191.0 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Mt_ATP-synt_B PF05405.14 EGO54137.1 - 0.063 12.9 8.0 0.1 12.2 8.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) PSCyt1 PF07635.11 EGO54137.1 - 0.077 13.6 0.3 0.28 11.8 0.1 2.1 1 1 1 2 2 2 0 Planctomycete cytochrome C Suf PF05843.14 EGO54137.1 - 1.5 8.8 9.0 1.7 8.5 9.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Rad4 PF03835.15 EGO54139.1 - 6e-27 94.1 3.7 8.7e-27 93.6 0.0 2.7 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EGO54139.1 - 7.1e-25 87.2 0.1 1.3e-24 86.4 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EGO54139.1 - 2.5e-22 78.5 0.0 6.9e-22 77.0 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EGO54139.1 - 2e-19 70.3 0.0 2e-19 70.3 0.0 4.4 4 1 0 4 4 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EGO54139.1 - 7.7e-05 23.1 0.0 0.0043 17.5 0.1 3.1 2 1 0 2 2 2 1 Transglutaminase-like superfamily RNA_polI_A34 PF08208.11 EGO54139.1 - 0.22 11.6 14.1 1.1 9.3 14.1 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 RPN2_C PF18004.1 EGO54139.1 - 0.29 11.0 11.7 6.1 6.7 10.1 2.7 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Paf1 PF03985.13 EGO54139.1 - 0.68 8.9 18.1 1.3 7.9 18.1 1.4 1 0 0 1 1 1 0 Paf1 Coilin_N PF15862.5 EGO54139.1 - 1.6 8.6 7.0 4.8 7.0 7.0 1.8 1 0 0 1 1 1 0 Coilin N-terminus Connexin PF00029.19 EGO54139.1 - 3.7 7.2 4.3 6.5 6.4 4.3 1.3 1 0 0 1 1 1 0 Connexin CPSF100_C PF13299.6 EGO54139.1 - 4.8 7.3 11.3 0.41 10.8 5.7 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 EGO54139.1 - 9.3 6.0 15.2 0.87 9.4 8.1 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 ADH_N PF08240.12 EGO54140.1 - 7e-23 80.6 7.1 7e-23 80.6 7.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO54140.1 - 2.4e-18 66.4 0.1 7e-18 64.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGO54140.1 - 0.00025 20.5 0.1 0.00043 19.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EGO54140.1 - 0.0039 16.5 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FeoC PF09012.10 EGO54140.1 - 0.62 10.2 0.1 0.62 10.2 0.1 2.2 3 0 0 3 3 3 0 FeoC like transcriptional regulator SET PF00856.28 EGO54142.1 - 0.11 12.9 0.1 1.7 9.0 0.1 2.6 1 1 0 1 1 1 0 SET domain DUF3558 PF12079.8 EGO54142.1 - 0.77 9.7 4.2 1.3 9.0 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Myosin_tail_1 PF01576.19 EGO54143.1 - 5.7e-05 21.2 56.6 5.7e-05 21.2 56.6 5.6 1 1 3 4 4 4 2 Myosin tail Apolipoprotein PF01442.18 EGO54143.1 - 0.00028 20.8 34.2 0.00028 20.8 34.2 9.5 1 1 8 9 9 9 2 Apolipoprotein A1/A4/E domain CENP-F_leu_zip PF10473.9 EGO54143.1 - 0.0026 17.8 24.0 0.0026 17.8 24.0 11.9 3 2 10 13 13 13 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.22 EGO54143.1 - 0.0046 17.2 8.5 0.0046 17.2 8.5 15.9 2 1 14 16 16 16 2 Seryl-tRNA synthetase N-terminal domain Filament PF00038.21 EGO54143.1 - 0.83 9.2 209.1 0.39 10.2 24.9 7.2 1 1 4 5 5 5 0 Intermediate filament protein Zn_clus PF00172.18 EGO54144.1 - 7.2e-10 38.8 12.3 1.2e-09 38.2 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Copper-fist PF00649.18 EGO54145.1 - 2.4e-22 78.1 3.5 2.4e-22 78.1 3.5 3.9 1 1 2 4 4 4 1 Copper fist DNA binding domain Leu_leader PF08054.11 EGO54145.1 - 0.21 11.2 0.2 7.2 6.3 0.1 2.2 2 0 0 2 2 2 0 Leucine operon leader peptide ApbA PF02558.16 EGO54148.1 - 6.1e-31 107.1 0.0 8.6e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EGO54148.1 - 6.1e-25 87.8 0.0 1.1e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pyr_redox PF00070.27 EGO54148.1 - 0.11 13.0 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GFO_IDH_MocA PF01408.22 EGO54148.1 - 0.12 13.2 0.0 0.21 12.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Lycopene_cycl PF05834.12 EGO54148.1 - 0.2 10.6 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein PHY PF00360.20 EGO54151.1 - 5e-29 100.9 0.0 9.7e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 EGO54151.1 - 3.9e-20 72.4 0.2 8.8e-20 71.3 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGO54151.1 - 1.6e-17 63.6 0.0 3e-16 59.6 0.0 2.5 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 EGO54151.1 - 2.5e-13 50.8 0.0 1.3e-12 48.4 0.0 2.2 2 0 0 2 2 2 1 GAF domain HisKA PF00512.25 EGO54151.1 - 1.3e-12 47.5 1.0 5.1e-12 45.6 1.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 EGO54151.1 - 1.4e-07 32.1 0.0 4.5e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 EGO54151.1 - 0.00036 20.5 0.1 0.00092 19.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 EGO54151.1 - 0.0013 18.6 0.3 0.0034 17.2 0.3 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HET PF06985.11 EGO54152.1 - 2.2e-18 67.0 0.0 3.7e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Kp4 PF09044.10 EGO54152.1 - 0.031 14.4 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 Kp4 Mito_carr PF00153.27 EGO54155.1 - 4.5e-53 177.1 0.9 2.1e-18 66.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 EGO54155.1 - 0.0042 17.4 0.7 0.021 15.2 0.2 2.3 2 1 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family RCC1 PF00415.18 EGO54156.1 - 1.3e-22 80.1 0.0 6.9e-06 26.6 0.0 4.9 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EGO54156.1 - 1.5e-11 44.5 0.0 2.9e-10 40.3 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain Ank_4 PF13637.6 EGO54156.1 - 1.2e-10 41.7 0.2 3.6e-10 40.2 0.1 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.6 EGO54156.1 - 1.2e-06 28.1 0.1 1.2e-06 28.1 0.1 4.1 6 0 0 6 6 6 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.6 EGO54156.1 - 9.2e-05 22.6 0.2 0.44 11.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EGO54156.1 - 9.3e-05 22.9 0.1 0.00021 21.8 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGO54156.1 - 0.02 15.2 0.1 0.085 13.2 0.1 2.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) TFIIA PF03153.13 EGO54156.1 - 0.28 11.1 18.1 0.55 10.2 18.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 EGO54156.1 - 4.9 6.9 15.9 4.6 7.0 1.8 2.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 ATG13 PF10033.9 EGO54157.1 - 8.3e-69 231.9 0.0 1.2e-68 231.4 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 VHS PF00790.19 EGO54158.1 - 1.4e-36 125.4 0.4 3e-36 124.4 0.4 1.6 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 EGO54158.1 - 1.3e-15 56.7 0.1 2.7e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGO54158.1 - 1.6e-14 53.5 0.1 3e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGO54158.1 - 3.7e-13 48.9 0.0 7.4e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 EGO54158.1 - 2e-10 40.8 1.8 2.8e-10 40.4 0.5 2.0 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 EGO54158.1 - 0.0098 15.8 6.6 0.024 14.6 6.6 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif YL1 PF05764.13 EGO54159.1 - 0.0016 18.6 22.3 0.0025 18.0 22.3 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Cadherin_tail PF15974.5 EGO54159.1 - 0.012 16.0 6.5 0.012 16.0 6.5 2.2 2 1 0 2 2 2 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region RPN2_C PF18004.1 EGO54159.1 - 0.016 15.1 15.8 0.016 15.1 15.8 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain RNA_polI_A34 PF08208.11 EGO54159.1 - 0.021 14.9 25.8 0.021 14.9 25.8 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Coilin_N PF15862.5 EGO54159.1 - 0.13 12.1 25.1 1.1 9.0 1.3 2.2 2 0 0 2 2 2 0 Coilin N-terminus eIF3_subunit PF08597.10 EGO54159.1 - 1.2 9.0 26.9 1.5 8.6 19.9 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Cytomega_UL84 PF06284.11 EGO54159.1 - 1.3 7.4 11.2 1.8 6.9 11.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein SR-25 PF10500.9 EGO54159.1 - 1.4 8.5 27.1 0.041 13.5 15.5 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Vfa1 PF08432.10 EGO54159.1 - 1.4 9.2 26.7 0.75 10.1 19.5 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF1764 PF08576.10 EGO54159.1 - 1.6 9.7 22.5 2.2 9.2 15.3 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) SMN PF06003.12 EGO54159.1 - 2.1 7.6 8.9 3 7.0 8.9 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Peptidase_S64 PF08192.11 EGO54159.1 - 3.1 6.2 12.5 3.9 5.9 12.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 LAP1C PF05609.12 EGO54159.1 - 3.2 6.7 17.5 3.9 6.5 17.5 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Rtf2 PF04641.12 EGO54159.1 - 3.2 7.0 22.4 5 6.4 22.4 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger Protocadherin PF08374.11 EGO54159.1 - 6 6.8 10.9 0.53 10.2 5.7 1.9 2 0 0 2 2 2 0 Protocadherin Spt20 PF12090.8 EGO54159.1 - 6.1 6.4 18.0 0.84 9.2 5.4 2.1 2 0 0 2 2 2 0 Spt20 family CCDC53 PF10152.9 EGO54159.1 - 6.6 7.1 13.1 8 6.9 6.9 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF3381 PF11861.8 EGO54159.1 - 9.2 6.0 31.5 1.5 8.6 22.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF2461 PF09365.10 EGO54162.1 - 2.6e-79 266.0 0.0 3.5e-79 265.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) CCSAP PF15748.5 EGO54162.1 - 0.028 14.6 11.3 0.046 13.9 11.3 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated eIF-3c_N PF05470.12 EGO54162.1 - 0.031 12.6 2.6 0.038 12.3 2.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Zip PF02535.22 EGO54162.1 - 0.7 9.0 1.5 0.81 8.8 1.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Trypan_PARP PF05887.11 EGO54162.1 - 0.87 9.6 10.7 1.9 8.5 10.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NPR3 PF03666.13 EGO54162.1 - 1.2 7.8 8.3 1.7 7.4 8.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 EGO54162.1 - 2.2 7.1 4.5 3.4 6.5 4.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 EGO54162.1 - 2.4 6.9 6.9 3.2 6.4 6.9 1.1 1 0 0 1 1 1 0 Presenilin MCM_bind PF09739.9 EGO54162.1 - 5.1 5.4 6.6 7.2 4.9 6.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Pox_Ag35 PF03286.14 EGO54162.1 - 5.9 6.6 17.4 11 5.7 17.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pectate_lyase_3 PF12708.7 EGO54163.1 - 6.2e-99 330.2 22.4 4.4e-86 288.2 6.6 3.1 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EGO54163.1 - 2.8e-06 26.9 0.8 0.035 13.8 0.1 2.5 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Fungal_trans PF04082.18 EGO54164.1 - 2.4e-09 36.6 0.5 0.00089 18.4 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Cyclin_N PF00134.23 EGO54165.1 - 5.8e-15 55.2 0.0 1.1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EGO54165.1 - 4.7e-07 30.3 0.1 4.7e-07 30.3 0.1 1.9 2 0 0 2 2 2 1 Cyclin DUF4887 PF16228.5 EGO54165.1 - 0.021 15.0 1.1 0.031 14.4 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) TAF4 PF05236.14 EGO54165.1 - 0.17 11.6 3.4 0.17 11.6 2.1 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family MRI PF15325.6 EGO54165.1 - 0.43 11.7 5.5 0.41 11.7 4.0 1.7 2 0 0 2 2 2 0 Modulator of retrovirus infection Pkinase PF00069.25 EGO54169.1 - 2.9e-70 236.7 0.0 4e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO54169.1 - 8.4e-31 107.2 0.0 1.1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO54169.1 - 0.0012 17.9 0.0 0.02 13.9 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EGO54169.1 - 0.0014 18.0 0.0 0.0024 17.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGO54169.1 - 0.0045 16.9 0.0 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGO54169.1 - 0.027 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 2OG-FeII_Oxy_2 PF13532.6 EGO54170.1 - 1.2e-29 104.0 0.0 1.9e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LapA_dom PF06305.11 EGO54173.1 - 0.18 11.6 0.6 1.1 9.1 0.3 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4709 PF15821.5 EGO54173.1 - 0.2 11.9 0.1 0.35 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) PhoR PF11808.8 EGO54173.1 - 0.38 11.2 3.9 0.49 10.8 0.0 3.0 4 0 0 4 4 4 0 Phosphate regulon sensor protein PhoR DUF3810 PF12725.7 EGO54173.1 - 1.6 8.0 6.3 8.1 5.7 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) 2-Hacid_dh_C PF02826.19 EGO54174.1 - 5.6e-45 152.9 0.0 7.2e-45 152.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGO54174.1 - 2e-05 24.2 0.0 7.8e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_7 PF13241.6 EGO54174.1 - 0.024 15.1 0.0 0.057 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 EGO54174.1 - 0.084 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase baeRF_family2 PF18844.1 EGO54174.1 - 0.1 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 XdhC_C PF13478.6 EGO54174.1 - 0.15 12.5 0.0 0.36 11.4 0.0 1.6 2 0 0 2 2 2 0 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 EGO54174.1 - 0.19 11.8 0.0 0.65 10.1 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Acetyltransf_2 PF00797.17 EGO54175.1 - 5.4e-45 154.1 0.3 2e-44 152.2 0.3 1.7 1 1 0 1 1 1 1 N-acetyltransferase NTP_transf_9 PF04248.12 EGO54175.1 - 0.001 18.9 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF427) HTH_33 PF13592.6 EGO54175.1 - 0.1 12.2 0.0 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix SGL PF08450.12 EGO54176.1 - 7.2e-06 25.8 0.1 0.00044 19.9 0.0 2.3 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Beta_propel PF09826.9 EGO54176.1 - 0.011 14.6 0.2 0.019 13.9 0.2 1.3 1 0 0 1 1 1 0 Beta propeller domain DUF4993 PF16384.5 EGO54176.1 - 0.021 13.8 0.1 0.033 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function RCC1_2 PF13540.6 EGO54176.1 - 0.03 14.1 4.2 2.3 8.1 0.5 3.4 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat Lactonase PF10282.9 EGO54176.1 - 0.081 12.2 0.1 1.2 8.4 0.0 2.6 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Lipoprotein_15 PF03640.15 EGO54176.1 - 0.3 10.7 2.8 0.2 11.2 0.3 2.1 2 0 0 2 2 2 0 Secreted repeat of unknown function DUF4448 PF14610.6 EGO54177.1 - 1.4e-32 113.0 0.0 2.3e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) CENP-B_dimeris PF09026.10 EGO54177.1 - 0.18 12.2 9.6 0.33 11.4 9.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Exo_endo_phos PF03372.23 EGO54179.1 - 4e-06 26.5 0.0 7.2e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Adenylsucc_synt PF00709.21 EGO54180.1 - 8.7e-169 561.9 0.0 9.8e-169 561.7 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF3716 PF12511.8 EGO54181.1 - 7.6e-15 54.7 2.0 1.2e-14 54.0 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) CAP_N PF01213.19 EGO54181.1 - 0.25 10.8 2.5 0.59 9.6 2.5 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RNA_pol_3_Rpc31 PF11705.8 EGO54181.1 - 0.41 10.9 12.2 0.73 10.0 12.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 EGO54181.1 - 0.41 9.9 8.9 0.65 9.3 8.9 1.2 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 EGO54181.1 - 0.57 9.5 9.0 0.85 8.9 9.0 1.3 1 0 0 1 1 1 0 BUD22 Astro_capsid_p PF12226.8 EGO54181.1 - 1.5 7.9 6.1 2.2 7.4 6.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 EGO54181.1 - 2.5 6.2 14.8 3.3 5.8 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family VIR_N PF15912.5 EGO54181.1 - 4.5 6.8 17.0 2.9 7.4 4.7 2.2 2 0 0 2 2 2 0 Virilizer, N-terminal CDC45 PF02724.14 EGO54181.1 - 7.7 4.7 9.4 11 4.1 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Pectate_lyase_3 PF12708.7 EGO54182.1 - 7.9e-93 310.2 9.7 3.8e-85 285.1 2.5 4.0 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EGO54182.1 - 9.8e-05 22.0 4.8 0.18 11.5 0.3 3.1 2 1 1 3 3 3 2 N terminal extension of bacteriophage endosialidase Mucin PF01456.17 EGO54182.1 - 2.4 8.1 40.8 0.14 12.2 34.9 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Nuc_sug_transp PF04142.15 EGO54183.1 - 1.8e-98 329.6 11.8 2.9e-98 328.9 11.8 1.2 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EGO54183.1 - 3e-08 33.3 12.6 9.7e-08 31.6 12.0 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGO54183.1 - 2.3e-07 31.1 24.7 0.0002 21.6 4.2 2.6 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 EGO54183.1 - 1.5e-05 24.5 14.6 0.0056 16.1 7.2 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family Halogen_Hydrol PF10112.9 EGO54183.1 - 0.11 12.6 0.4 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein UPF0146 PF03686.13 EGO54183.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) DMT_6 PF04342.12 EGO54183.1 - 3.2 8.0 7.7 4.6 7.5 0.6 2.9 3 0 0 3 3 3 0 Putative member of DMT superfamily (DUF486) Sec63 PF02889.16 EGO54185.1 - 9.6e-27 93.8 0.0 1.5e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EGO54185.1 - 1.3e-25 90.2 0.0 3.1e-25 89.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGO54185.1 - 3.1e-12 46.8 0.0 7.1e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGO54185.1 - 4.6e-11 43.1 0.0 2.8e-09 37.3 0.0 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 EGO54185.1 - 6.8e-05 23.4 0.0 0.00022 21.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_30 PF13604.6 EGO54185.1 - 0.00062 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGO54185.1 - 0.0011 19.3 0.1 0.014 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Cdd1 PF11731.8 EGO54185.1 - 0.0035 17.5 0.0 0.009 16.2 0.0 1.7 1 0 0 1 1 1 1 Pathogenicity locus AAA_22 PF13401.6 EGO54185.1 - 0.0061 16.8 0.0 0.019 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EGO54185.1 - 0.077 12.8 0.2 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 Helicase DNA_pol_lambd_f PF10391.9 EGO54185.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Bac_rhamnosid_C PF17390.2 EGO54185.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain Apc15p PF05841.11 EGO54185.1 - 3 8.7 8.5 1.1 10.1 2.3 2.8 3 0 0 3 3 2 0 Apc15p protein GFO_IDH_MocA PF01408.22 EGO54186.1 - 4.5e-19 69.4 0.4 8.4e-19 68.6 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGO54186.1 - 0.0063 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain LodA_C PF18417.1 EGO54186.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 L-lysine epsilon oxidase C-terminal domain GvpG PF05120.12 EGO54186.1 - 0.13 12.3 0.6 0.34 11.0 0.6 1.7 1 0 0 1 1 1 0 Gas vesicle protein G MFS_1 PF07690.16 EGO54187.1 - 7.7e-30 104.0 23.5 7.7e-30 104.0 23.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TetR_C_8 PF14278.6 EGO54187.1 - 0.07 13.2 0.1 0.45 10.6 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region NDUF_B8 PF05821.11 EGO54187.1 - 0.14 12.0 0.0 0.9 9.4 0.0 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) GMC_oxred_N PF00732.19 EGO54190.1 - 8.5e-59 199.3 0.0 1.1e-58 199.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO54190.1 - 1.2e-30 106.9 0.0 1.8e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EGO54190.1 - 1.8e-05 24.0 0.0 2.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EGO54190.1 - 5.4e-05 23.3 0.1 0.00011 22.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGO54190.1 - 9.8e-05 21.6 0.0 0.019 14.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EGO54190.1 - 0.00018 21.2 0.9 0.0023 17.6 0.9 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO54190.1 - 0.00042 19.6 0.0 0.00078 18.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO54190.1 - 0.08 11.6 0.1 0.16 10.6 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EGO54190.1 - 0.084 12.1 0.2 0.46 9.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 EGO54190.1 - 0.1 11.8 0.1 14 4.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO54190.1 - 0.11 13.1 0.1 1.5 9.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mem_trans PF03547.18 EGO54191.1 - 4.6e-19 68.1 1.4 6.7e-19 67.5 1.4 1.2 1 0 0 1 1 1 1 Membrane transport protein PhoLip_ATPase_C PF16212.5 EGO54191.1 - 0.023 14.4 6.1 0.17 11.6 2.7 2.2 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal TauD PF02668.16 EGO54192.1 - 9.2e-44 150.2 0.1 1.3e-43 149.7 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Plasmod_MYXSPDY PF07981.11 EGO54192.1 - 0.27 11.3 1.3 0.48 10.5 0.1 2.0 2 0 0 2 2 2 0 Plasmodium repeat_MYXSPDY Carb_anhydrase PF00194.21 EGO54193.1 - 2.2e-28 99.5 0.0 9.2e-14 51.6 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase HEAT PF02985.22 EGO54195.1 - 2.1e-12 46.2 4.7 0.011 15.9 0.0 8.5 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 EGO54195.1 - 3.7e-12 46.5 12.2 1.3e-05 25.6 0.0 8.3 9 1 1 10 10 8 3 HEAT-like repeat HEAT_2 PF13646.6 EGO54195.1 - 1.1e-10 41.8 10.9 1 9.8 0.0 8.3 8 3 2 10 10 9 3 HEAT repeats IBN_N PF03810.19 EGO54195.1 - 4.6e-09 36.1 0.2 3.3e-08 33.3 0.1 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 EGO54195.1 - 1e-07 32.4 0.0 0.071 13.7 0.0 4.4 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region Arm PF00514.23 EGO54195.1 - 2.2e-07 30.7 0.8 0.031 14.3 0.0 6.8 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EGO54195.1 - 9.9e-07 28.9 1.3 0.023 14.8 0.0 4.3 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGO54195.1 - 8.7e-06 25.5 0.3 0.012 15.2 0.0 4.9 5 1 1 6 6 6 1 CLASP N terminal ParcG PF10274.9 EGO54195.1 - 1.4e-05 25.3 1.1 4.6 7.3 0.0 4.4 4 1 1 5 5 5 3 Parkin co-regulated protein IFRD PF05004.13 EGO54195.1 - 0.00084 18.5 1.6 0.19 10.8 0.2 4.0 3 1 0 3 3 3 1 Interferon-related developmental regulator (IFRD) TIP120 PF08623.10 EGO54195.1 - 0.0011 18.8 0.6 0.012 15.4 0.0 3.1 3 1 0 3 3 3 1 TATA-binding protein interacting (TIP20) DUF3730 PF12530.8 EGO54195.1 - 0.0058 16.2 0.1 1.3 8.5 0.0 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF3730) DUF577 PF04510.12 EGO54195.1 - 0.01 15.8 0.1 0.084 12.8 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF577) Adaptin_N PF01602.20 EGO54195.1 - 0.012 14.2 6.8 0.14 10.7 0.1 4.3 3 2 2 5 5 5 0 Adaptin N terminal region RTP1_C1 PF10363.9 EGO54195.1 - 0.03 14.5 0.9 9.4 6.5 0.0 4.4 3 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3887 PF13026.6 EGO54195.1 - 0.082 13.7 0.1 3.6 8.5 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3887) RTA1 PF04479.13 EGO54196.1 - 1e-69 234.3 11.2 1.5e-69 233.7 11.2 1.3 1 0 0 1 1 1 1 RTA1 like protein zf-C2H2_4 PF13894.6 EGO54197.1 - 0.066 14.1 3.7 4.4 8.4 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger TT_ORF2 PF02957.15 EGO54197.1 - 0.17 12.8 3.1 0.32 11.9 0.5 2.7 3 0 0 3 3 3 0 TT viral ORF2 zf-C2H2_6 PF13912.6 EGO54197.1 - 0.18 11.8 4.9 0.13 12.3 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4188 PF13826.6 EGO54198.1 - 1.6e-32 112.3 0.3 2.3e-32 111.8 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 EGO54198.1 - 0.091 12.1 0.5 0.12 11.7 0.5 1.2 1 0 0 1 1 1 0 Haem-containing dehydratase TFIIA PF03153.13 EGO54199.1 - 0.034 14.1 26.1 0.063 13.3 26.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dapper PF15268.6 EGO54199.1 - 4.7 6.0 26.9 6.4 5.5 26.9 1.1 1 0 0 1 1 1 0 Dapper LUC7 PF03194.15 EGO54200.1 - 2.8e-70 236.8 0.1 3.4e-70 236.6 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Gpi16 PF04113.14 EGO54201.1 - 1.3e-251 836.0 0.0 1.6e-251 835.6 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component FUSC PF04632.12 EGO54201.1 - 0.094 11.2 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FAD_binding_3 PF01494.19 EGO54202.1 - 4.4e-14 52.5 0.0 9.6e-11 41.5 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EGO54202.1 - 4.8e-06 26.7 0.0 9.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO54202.1 - 0.00012 21.8 0.1 0.00027 20.6 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO54202.1 - 0.0017 17.6 0.0 0.029 13.6 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO54202.1 - 0.011 15.1 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 EGO54202.1 - 0.044 12.6 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Mqo PF06039.15 EGO54202.1 - 0.053 12.1 0.0 0.084 11.4 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) SE PF08491.10 EGO54202.1 - 0.076 12.0 0.0 0.21 10.6 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox PF00070.27 EGO54202.1 - 0.11 13.1 0.0 8.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_1e PF01406.19 EGO54203.1 - 1.7e-105 352.7 0.0 5.8e-105 350.9 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGO54203.1 - 0.00031 19.6 0.3 0.18 10.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 EGO54203.1 - 0.00051 20.5 0.0 0.0018 18.7 0.0 2.0 1 0 0 1 1 1 1 DALR domain tRNA-synt_1c PF00749.21 EGO54203.1 - 0.00096 18.1 0.9 0.0046 15.9 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain PGA2 PF07543.12 EGO54203.1 - 2.3 8.2 9.3 7.1 6.6 9.3 1.8 1 0 0 1 1 1 0 Protein trafficking PGA2 Nuc_deoxyri_tr2 PF15891.5 EGO54204.1 - 2.9e-35 120.8 0.0 3.7e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like Nuc_deoxyrib_tr PF05014.15 EGO54204.1 - 0.017 15.2 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase DUF3716 PF12511.8 EGO54205.1 - 7.8e-17 61.1 1.5 1.7e-16 60.0 1.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Cupin_3 PF05899.12 EGO54205.1 - 0.1 12.3 0.0 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) NOA36 PF06524.12 EGO54205.1 - 3 7.1 6.7 5.7 6.2 6.7 1.4 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 EGO54208.1 - 4.3e-32 111.5 0.1 1.5e-30 106.5 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO54208.1 - 4.2e-23 82.0 0.0 7.5e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CENP-F_N PF10481.9 EGO54208.1 - 0.0036 17.0 5.7 0.0036 17.0 5.7 1.9 2 0 0 2 2 2 1 Cenp-F N-terminal domain FapA PF03961.13 EGO54208.1 - 0.023 13.3 3.1 0.037 12.7 3.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 EGO54208.1 - 0.051 12.5 7.7 0.094 11.6 7.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_Mu_Gam PF07352.12 EGO54208.1 - 0.051 13.5 2.6 0.11 12.4 2.6 1.5 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein CdvA PF18822.1 EGO54208.1 - 0.057 13.2 6.3 0.14 12.0 6.3 1.6 1 0 0 1 1 1 0 CdvA-like coiled-coil domain DUF3450 PF11932.8 EGO54208.1 - 0.14 11.5 4.6 0.25 10.6 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APH PF01636.23 EGO54208.1 - 0.19 11.6 1.6 0.97 9.3 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family TMPIT PF07851.13 EGO54208.1 - 0.84 8.8 3.0 9.3 5.4 4.9 1.7 2 0 0 2 2 2 0 TMPIT-like protein LCD1 PF09798.9 EGO54208.1 - 0.97 7.9 3.4 1.4 7.4 2.9 1.4 2 0 0 2 2 2 0 DNA damage checkpoint protein Fungal_TACC PF12709.7 EGO54208.1 - 1.6 9.2 7.9 7.5 7.1 5.7 2.4 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Exonuc_VII_L PF02601.15 EGO54208.1 - 2.5 7.6 7.3 0.69 9.4 2.9 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit Atg14 PF10186.9 EGO54208.1 - 3.4 6.7 9.5 1.6 7.7 3.7 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_1 PF00170.21 EGO54209.1 - 0.00023 21.2 4.9 0.00057 19.9 4.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor Complex1_LYR PF05347.15 EGO54211.1 - 1.4e-09 37.9 1.6 2.5e-09 37.0 0.1 2.3 2 0 0 2 2 2 1 Complex 1 protein (LYR family) AT_hook PF02178.19 EGO54211.1 - 0.00064 19.3 25.3 0.15 12.1 4.1 4.0 3 0 0 3 3 3 3 AT hook motif UQ_con PF00179.26 EGO54212.1 - 2.4e-12 46.7 0.3 4.3e-12 45.9 0.3 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGO54212.1 - 0.0053 17.0 0.0 0.0056 16.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain E1_4HB PF16191.5 EGO54212.1 - 0.06 13.5 0.0 0.15 12.3 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle DCB PF16213.5 EGO54213.1 - 4.4e-47 160.0 8.7 1e-45 155.6 8.4 2.8 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EGO54213.1 - 4.3e-35 121.0 1.5 1.1e-33 116.3 0.0 3.5 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 EGO54213.1 - 2.3e-26 92.3 4.2 5.7e-20 71.1 0.6 3.6 3 0 0 3 3 3 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 EGO54213.1 - 4.7e-06 26.4 0.5 0.0019 18.0 0.0 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) GREB1 PF15782.5 EGO54213.1 - 0.22 8.6 0.0 0.38 7.8 0.0 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Utp12 PF04003.12 EGO54213.1 - 0.33 11.3 5.3 17 5.8 0.1 5.3 5 1 1 6 6 6 0 Dip2/Utp12 Family Band_7 PF01145.25 EGO54214.1 - 3.4e-30 105.4 0.6 3.4e-30 105.4 0.6 2.2 3 0 0 3 3 3 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EGO54214.1 - 1.5e-24 85.8 1.2 1.5e-24 85.8 1.2 2.5 2 0 0 2 2 2 1 C-terminal region of band_7 Pox_A11 PF05061.13 EGO54214.1 - 0.026 13.8 0.5 0.043 13.1 0.5 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein Glyco_transf_21 PF13506.6 EGO54214.1 - 0.059 12.8 0.5 0.15 11.5 0.4 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 21 Lactamase_B_2 PF12706.7 EGO54218.1 - 9.3e-24 84.1 0.0 2.3e-21 76.3 0.0 2.5 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGO54218.1 - 9.5e-05 22.3 0.0 0.00024 21.0 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGO54218.1 - 0.0064 16.5 0.7 0.042 13.9 0.7 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Cupin_2 PF07883.11 EGO54219.1 - 2.4e-08 33.6 0.1 1.1e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 EGO54219.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Ppnp PF06865.11 EGO54219.1 - 0.16 12.4 0.2 21 5.6 0.0 2.2 2 0 0 2 2 2 0 Pyrimidine/purine nucleoside phosphorylase DUF2179 PF10035.9 EGO54221.1 - 0.023 14.4 0.1 0.043 13.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) Sugar_tr PF00083.24 EGO54222.1 - 5.4e-123 411.2 18.5 6.1e-123 411.0 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO54222.1 - 2.9e-24 85.7 35.4 7.5e-17 61.3 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SGL PF08450.12 EGO54223.1 - 1.8e-07 31.0 0.3 6.2e-06 26.0 0.6 2.2 1 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region DUF4185 PF13810.6 EGO54224.1 - 1.7e-16 60.4 3.3 2.3e-16 59.9 3.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Asparaginase_2 PF01112.18 EGO54225.1 - 7.6e-58 195.9 0.6 7.3e-29 100.8 0.1 3.8 3 1 0 3 3 3 3 Asparaginase Tim17 PF02466.19 EGO54226.1 - 3.3e-32 111.2 7.3 4.3e-32 110.8 7.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Peptidase_M20 PF01546.28 EGO54227.1 - 3.2e-23 82.5 0.0 2.9e-22 79.4 0.0 2.3 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 EGO54227.1 - 6e-15 55.4 4.5 0.0066 17.3 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.14 EGO54227.1 - 2.9e-06 27.2 0.0 5.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGO54227.1 - 0.0035 17.1 0.0 0.0078 15.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Sporozoite_P67 PF05642.11 EGO54227.1 - 0.15 10.1 3.0 0.26 9.3 3.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nup160 PF11715.8 EGO54227.1 - 0.16 10.6 2.1 0.83 8.2 0.1 2.6 2 1 0 3 3 3 0 Nucleoporin Nup120/160 zf-RING_2 PF13639.6 EGO54228.1 - 0.017 15.4 0.4 0.017 15.4 0.4 2.9 3 1 0 3 3 3 0 Ring finger domain zf-RING_UBOX PF13445.6 EGO54228.1 - 0.056 13.5 3.9 0.21 11.7 2.3 2.7 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EGO54228.1 - 0.16 11.8 4.4 2.2 8.2 4.4 2.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO54228.1 - 0.32 11.0 6.1 0.89 9.6 5.1 2.4 1 1 1 2 2 2 0 zinc-RING finger domain CVNH PF08881.10 EGO54229.1 - 3.5e-07 30.8 0.0 5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 CVNH domain BLM10_mid PF16507.5 EGO54230.1 - 5.6e-203 675.3 0.0 7.9e-203 674.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EGO54230.1 - 1.4e-29 101.8 0.0 1e-28 99.0 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 EGO54230.1 - 2.7e-21 75.6 0.0 9.7e-21 73.9 0.0 2.1 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal HTH_32 PF13565.6 EGO54231.1 - 0.045 14.4 2.5 0.16 12.6 0.0 2.0 1 1 1 2 2 2 0 Homeodomain-like domain CAP PF00188.26 EGO54232.1 - 2.9e-14 54.0 2.6 4.1e-14 53.5 2.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PAP1 PF08601.10 EGO54232.1 - 1.1 8.9 7.8 1.3 8.6 7.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 RAP1 PF07218.11 EGO54232.1 - 8.3 4.5 6.1 10 4.3 6.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) YabA PF06156.13 EGO54233.1 - 0.021 15.4 0.3 0.051 14.2 0.3 1.7 1 0 0 1 1 1 0 Initiation control protein YabA DUF724 PF05266.14 EGO54233.1 - 0.046 13.6 1.4 0.076 12.8 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) APG6_N PF17675.1 EGO54233.1 - 0.087 13.4 3.4 0.18 12.3 3.4 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region EzrA PF06160.12 EGO54233.1 - 0.16 10.1 0.9 0.23 9.6 0.9 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF1690 PF07956.11 EGO54233.1 - 0.18 12.2 4.9 0.66 10.4 3.7 2.2 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Cgr1 PF03879.14 EGO54233.1 - 0.26 11.7 4.6 0.62 10.5 4.6 1.6 1 0 0 1 1 1 0 Cgr1 family DUF4407 PF14362.6 EGO54233.1 - 0.29 10.5 1.5 0.43 9.9 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2205 PF10224.9 EGO54233.1 - 0.31 11.1 3.8 0.74 9.9 3.8 1.6 1 0 0 1 1 1 0 Short coiled-coil protein Striatin PF08232.12 EGO54233.1 - 0.69 10.5 7.5 0.13 12.8 3.7 1.7 2 0 0 2 2 2 0 Striatin family Methyltransf_31 PF13847.6 EGO54234.1 - 4.2e-27 94.8 0.0 6.2e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO54234.1 - 1.6e-18 67.2 0.0 2.8e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO54234.1 - 1.5e-16 60.8 0.0 2.7e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO54234.1 - 3.4e-14 52.8 0.0 1.5e-13 50.6 0.0 2.0 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGO54234.1 - 1.3e-07 31.6 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO54234.1 - 1.1e-06 29.3 0.0 1.8e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGO54234.1 - 0.00011 21.5 0.0 0.00015 21.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 EGO54234.1 - 0.00062 19.6 0.0 0.0011 18.8 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EGO54234.1 - 0.0019 17.6 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EGO54234.1 - 0.0025 17.1 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 EGO54234.1 - 0.009 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase DOT1 PF08123.13 EGO54234.1 - 0.025 14.1 0.2 0.048 13.2 0.0 1.6 2 0 0 2 2 2 0 Histone methylation protein DOT1 AT_hook PF02178.19 EGO54236.1 - 0.42 10.7 5.7 1 9.5 5.7 1.7 1 0 0 1 1 1 0 AT hook motif DUF3716 PF12511.8 EGO54237.1 - 2.4e-16 59.5 4.8 5.1e-16 58.5 4.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) zf-C2H2_aberr PF17017.5 EGO54237.1 - 0.058 13.5 2.3 3.9 7.6 0.0 2.9 3 0 0 3 3 3 0 Aberrant zinc-finger Cwf_Cwc_15 PF04889.12 EGO54237.1 - 2.1 8.0 10.4 6.1 6.5 10.4 1.8 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein XkdW PF09636.10 EGO54238.1 - 0.019 15.1 1.2 0.019 15.1 1.2 2.4 2 0 0 2 2 2 0 XkdW protein VitD-bind_III PF09164.10 EGO54238.1 - 0.1 12.6 0.4 0.3 11.1 0.4 1.8 1 0 0 1 1 1 0 Vitamin D binding protein, domain III BBP1_C PF15272.6 EGO54238.1 - 0.96 9.2 12.5 1.7 8.4 12.5 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal V_ATPase_I PF01496.19 EGO54238.1 - 1.5 6.6 11.1 2.5 5.9 11.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1465 PF07323.12 EGO54238.1 - 3.2 7.6 11.7 0.3 10.9 4.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) TMEM154 PF15102.6 EGO54239.1 - 4.1 7.3 4.6 1.3 9.0 0.1 1.9 1 1 1 2 2 2 0 TMEM154 protein family FAT PF02259.23 EGO54240.1 - 3.9e-139 463.7 8.7 9e-139 462.5 8.7 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EGO54240.1 - 3.4e-74 249.8 0.1 6.1e-74 249.0 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EGO54240.1 - 3.2e-69 231.9 4.6 3.8e-65 218.7 0.1 4.9 4 1 1 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EGO54240.1 - 3.8e-45 152.3 0.4 3.8e-45 152.3 0.4 3.4 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain HEAT PF02985.22 EGO54240.1 - 5.4e-17 60.4 11.9 0.0019 18.3 0.0 10.5 10 0 0 10 10 10 3 HEAT repeat FATC PF02260.20 EGO54240.1 - 3e-14 52.5 0.1 1.2e-13 50.6 0.1 2.1 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 EGO54240.1 - 6.1e-12 45.8 6.4 0.0098 16.3 0.0 6.8 6 0 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 EGO54240.1 - 1.1e-09 38.6 11.3 0.12 12.9 0.0 9.9 8 2 2 10 10 9 2 HEAT-like repeat Adaptin_N PF01602.20 EGO54240.1 - 1.1e-08 34.1 5.2 0.00016 20.4 0.1 4.0 3 1 1 4 4 4 3 Adaptin N terminal region Cnd1 PF12717.7 EGO54240.1 - 4e-08 33.5 1.4 0.014 15.4 0.0 6.2 4 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGO54240.1 - 9.7e-05 22.0 3.2 1.5 8.3 0.0 5.0 4 1 1 5 5 5 2 CLASP N terminal DUF3730 PF12530.8 EGO54240.1 - 0.00059 19.5 0.6 3.2 7.2 0.0 4.4 4 0 0 4 4 4 1 Protein of unknown function (DUF3730) Vac14_Fab1_bd PF12755.7 EGO54240.1 - 0.00077 20.0 2.9 41 4.9 0.2 7.0 7 1 1 8 8 8 0 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 EGO54240.1 - 0.0034 17.1 0.0 2.2 8.0 0.0 3.8 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis Tti2 PF10521.9 EGO54240.1 - 0.029 13.9 2.7 3.9 6.9 0.0 3.6 3 0 0 3 3 3 0 Tti2 family ANAPC3 PF12895.7 EGO54240.1 - 0.12 12.6 2.6 11 6.3 0.0 4.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PRKCSH-like PF12999.7 EGO54241.1 - 1.7e-40 138.7 6.3 2.6e-23 82.7 0.3 2.9 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EGO54241.1 - 1.1e-30 106.4 3.6 5.5e-30 104.1 0.1 2.8 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EGO54241.1 - 2.2e-11 44.6 0.2 6e-11 43.2 0.2 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF773 PF05600.12 EGO54241.1 - 0.00024 20.0 3.5 0.00047 19.0 3.5 1.5 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 DFF-C PF09033.10 EGO54241.1 - 0.00033 20.6 0.1 0.00033 20.6 0.1 2.3 2 0 0 2 2 2 1 DNA Fragmentation factor 45kDa, C terminal domain ATG27 PF09451.10 EGO54241.1 - 0.0021 18.0 0.1 0.0058 16.5 0.1 1.7 1 0 0 1 1 1 1 Autophagy-related protein 27 Mod_r PF07200.13 EGO54241.1 - 0.012 15.7 11.8 0.069 13.3 0.2 2.8 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein NPV_P10 PF05531.12 EGO54241.1 - 0.015 15.8 2.5 0.069 13.6 0.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FTA4 PF13093.6 EGO54241.1 - 0.029 14.3 1.5 0.45 10.4 0.2 2.2 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 NuA4 PF09340.10 EGO54241.1 - 0.037 13.9 6.1 0.11 12.4 0.4 2.9 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 ATS PF15445.6 EGO54241.1 - 0.046 13.1 0.5 0.07 12.5 0.5 1.2 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 Ish1 PF10281.9 EGO54241.1 - 0.057 13.7 0.0 0.2 12.0 0.0 1.9 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein DUF948 PF06103.11 EGO54241.1 - 0.06 13.6 0.6 1.3 9.3 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.8 EGO54241.1 - 0.088 12.1 10.7 2.6 7.3 3.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) AAA_23 PF13476.6 EGO54241.1 - 0.12 12.9 4.3 0.25 11.8 4.3 1.5 1 0 0 1 1 1 0 AAA domain FlxA PF14282.6 EGO54241.1 - 0.12 12.3 4.7 0.1 12.6 0.9 2.3 2 0 0 2 2 2 0 FlxA-like protein BLOC1_2 PF10046.9 EGO54241.1 - 0.13 12.6 8.2 2.6 8.4 1.0 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF684 PF05075.14 EGO54241.1 - 0.13 11.2 2.5 0.09 11.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF684) Filament PF00038.21 EGO54241.1 - 0.16 11.5 14.8 1.8 8.0 8.3 2.3 2 0 0 2 2 2 0 Intermediate filament protein DUF1664 PF07889.12 EGO54241.1 - 0.17 12.0 4.3 7 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1515 PF07439.11 EGO54241.1 - 0.19 11.7 5.3 0.35 10.9 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) GAS PF13851.6 EGO54241.1 - 0.24 10.7 13.5 0.66 9.3 8.1 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 EGO54241.1 - 0.25 11.3 4.6 4 7.5 0.1 2.3 2 0 0 2 2 2 0 Laminin Domain II Tektin PF03148.14 EGO54241.1 - 0.29 9.9 10.6 2.9 6.5 5.5 2.3 2 0 0 2 2 2 0 Tektin family DUF1465 PF07323.12 EGO54241.1 - 0.52 10.1 5.2 1.9 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) PspB PF06667.12 EGO54241.1 - 0.75 9.9 8.7 0.35 10.9 0.3 2.4 2 0 0 2 2 2 0 Phage shock protein B APG6_N PF17675.1 EGO54241.1 - 0.86 10.1 20.7 8 7.0 0.4 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF4407 PF14362.6 EGO54241.1 - 0.86 8.9 17.1 0.91 8.8 10.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 EGO54241.1 - 1 9.6 8.3 1.6 8.9 0.4 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FapA PF03961.13 EGO54241.1 - 1.1 7.8 11.3 3.1 6.3 5.7 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A Jnk-SapK_ap_N PF09744.9 EGO54241.1 - 1.2 9.3 17.1 2.3 8.4 8.5 3.0 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF848 PF05852.11 EGO54241.1 - 2.3 8.3 8.2 1.1 9.4 0.5 2.4 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) TSC22 PF01166.18 EGO54241.1 - 2.4 8.5 5.6 6.5 7.2 0.6 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family GTP-bdg_M PF16360.5 EGO54241.1 - 3.1 8.5 13.4 0.098 13.3 3.2 3.1 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region DUF2721 PF11026.8 EGO54241.1 - 3.6 7.5 7.6 0.69 9.8 3.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) FAM184 PF15665.5 EGO54241.1 - 6.1 6.6 16.3 0.5 10.1 7.4 2.8 3 0 0 3 3 3 0 Family with sequence similarity 184, A and B Atg14 PF10186.9 EGO54241.1 - 6.2 5.8 12.5 0.057 12.5 0.7 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 EGO54241.1 - 6.2 6.6 9.7 1.7 8.4 4.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Fzo_mitofusin PF04799.13 EGO54241.1 - 6.4 6.3 6.8 3.9 7.0 2.4 2.1 2 0 0 2 2 2 0 fzo-like conserved region Phe_tRNA-synt_N PF02912.18 EGO54241.1 - 8.5 6.4 13.9 20 5.2 8.1 2.9 3 0 0 3 3 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain CREPT PF16566.5 EGO54241.1 - 8.7 6.5 9.9 29 4.8 0.2 2.5 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour CdvA PF18822.1 EGO54241.1 - 9.2 6.1 16.9 0.82 9.5 5.7 2.8 3 0 0 3 3 2 0 CdvA-like coiled-coil domain Apt1 PF10351.9 EGO54241.1 - 9.9 4.9 7.1 5.4 5.7 0.1 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain GCIP PF13324.6 EGO54242.1 - 1e-23 84.3 0.1 2.9e-23 82.8 0.1 1.6 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting YlbD_coat PF14071.6 EGO54242.1 - 0.011 16.0 1.5 0.083 13.2 1.0 2.2 2 0 0 2 2 2 0 Putative coat protein Nop14 PF04147.12 EGO54242.1 - 0.065 11.4 7.8 0.085 11.1 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 EGO54242.1 - 0.082 12.8 10.1 0.42 10.5 10.9 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region RNA_pol_3_Rpc31 PF11705.8 EGO54242.1 - 0.086 13.1 12.2 0.14 12.4 12.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Vfa1 PF08432.10 EGO54242.1 - 0.12 12.7 2.5 0.18 12.1 2.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_RNA_Pol_19 PF05320.12 EGO54242.1 - 0.16 11.9 5.1 0.27 11.2 5.1 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PDDEXK_6 PF04720.12 EGO54242.1 - 0.2 11.6 2.9 0.37 10.7 2.9 1.4 1 0 0 1 1 1 0 PDDEXK-like family of unknown function DUF4611 PF15387.6 EGO54242.1 - 0.26 11.6 14.5 1.9 8.8 13.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 EGO54242.1 - 0.26 11.7 15.2 0.91 10.0 15.4 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Dicty_REP PF05086.12 EGO54242.1 - 0.31 9.0 7.0 0.43 8.5 7.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDC45 PF02724.14 EGO54242.1 - 0.31 9.3 8.2 0.42 8.8 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EGO54242.1 - 0.34 9.4 11.8 0.56 8.7 11.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 EGO54242.1 - 0.66 9.3 9.3 1.1 8.6 9.3 1.3 1 0 0 1 1 1 0 BUD22 CotH PF08757.11 EGO54242.1 - 0.9 9.0 5.2 1.4 8.3 5.2 1.3 1 0 0 1 1 1 0 CotH kinase protein DNA_pol_phi PF04931.13 EGO54242.1 - 1.1 7.3 16.8 1.6 6.8 16.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 EGO54242.1 - 1.3 8.7 8.4 2.8 7.6 8.3 1.6 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 EGO54242.1 - 1.3 9.0 7.0 1.1 9.3 5.5 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 EGO54242.1 - 5.3 6.3 13.5 7.5 5.8 13.5 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4637 PF15470.6 EGO54242.1 - 7.5 6.3 10.0 12 5.6 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Cu-oxidase_2 PF07731.14 EGO54243.1 - 5e-42 142.9 7.2 8.4e-41 138.9 0.6 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGO54243.1 - 5.1e-30 103.9 2.5 7.8e-29 100.1 1.1 3.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EGO54243.1 - 1.5e-26 93.4 0.1 4e-26 92.0 0.0 1.7 2 0 0 2 2 2 1 Multicopper oxidase UPF0242 PF06785.11 EGO54245.1 - 0.0034 17.5 1.3 0.0068 16.5 1.3 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF2721 PF11026.8 EGO54245.1 - 0.037 13.9 0.2 0.079 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) UbiA PF01040.18 EGO54245.1 - 0.07 12.4 0.3 0.11 11.8 0.3 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family CENP-O PF09496.10 EGO54245.1 - 0.6 10.1 3.8 1.3 8.9 3.8 1.5 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component SbcD_C PF12320.8 EGO54245.1 - 0.65 10.3 4.9 1.9 8.8 4.9 1.8 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain V_ATPase_I PF01496.19 EGO54245.1 - 8.5 4.1 5.6 14 3.4 5.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DbpA PF03880.15 EGO54246.1 - 0.0083 16.1 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 DbpA RNA binding domain Cyto_heme_lyase PF01265.17 EGO54247.1 - 2.5e-117 391.6 1.1 3e-117 391.4 1.1 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ABC1 PF03109.16 EGO54248.1 - 7.5e-25 87.4 0.0 5e-15 55.7 0.0 2.7 3 0 0 3 3 3 2 ABC1 family APH PF01636.23 EGO54248.1 - 0.032 14.2 0.0 0.058 13.3 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Chalcone_3 PF16036.5 EGO54248.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Chalcone isomerase-like Glyco_hydro_71 PF03659.14 EGO54249.1 - 2e-101 339.5 2.2 2.3e-101 339.4 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Ribosomal_S28e PF01200.18 EGO54250.1 - 6.6e-31 106.1 2.3 7.3e-31 106.0 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e RhgB_N PF09284.10 EGO54251.1 - 1.3e-107 359.1 4.0 2.3e-107 358.2 4.0 1.4 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 EGO54251.1 - 3.4e-43 147.4 0.1 9.9e-43 145.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EGO54251.1 - 6.5e-23 80.3 4.2 6.5e-23 80.3 4.2 2.2 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 EGO54251.1 - 7.6e-06 26.1 3.5 7.6e-06 26.1 3.5 2.9 4 0 0 4 4 4 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EGO54251.1 - 0.013 15.5 1.9 0.018 15.0 0.2 2.2 2 0 0 2 2 2 0 CarboxypepD_reg-like domain DUF2012 PF09430.10 EGO54251.1 - 0.023 14.8 0.0 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Dus PF01207.17 EGO54251.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Sugar_tr PF00083.24 EGO54252.1 - 3.8e-91 306.2 15.6 4.3e-91 306.0 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO54252.1 - 1.3e-22 80.3 44.3 4.1e-16 58.9 21.6 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily CDH-cyt PF16010.5 EGO54254.1 - 5.6e-53 179.3 0.2 6.6e-53 179.1 0.2 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Aldo_ket_red PF00248.21 EGO54255.1 - 3.5e-55 187.3 0.0 4.5e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Bac_surface_Ag PF01103.23 EGO54256.1 - 5.5e-41 141.1 0.0 8.2e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.26 EGO54257.1 - 1.7e-19 69.9 0.1 2.4e-19 69.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO54257.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B ABC2_membrane PF01061.24 EGO54258.1 - 3.6e-92 307.5 52.5 5.2e-49 166.5 21.5 3.1 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 EGO54258.1 - 2.1e-38 130.1 7.6 1.3e-33 114.7 0.1 3.5 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 EGO54258.1 - 1.4e-35 122.7 0.0 1.2e-16 61.5 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 EGO54258.1 - 4.5e-19 68.9 0.1 1.2e-18 67.4 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EGO54258.1 - 2.9e-09 37.6 0.1 4.1e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EGO54258.1 - 1.7e-05 24.5 0.0 0.0006 19.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGO54258.1 - 5.6e-05 23.3 0.0 0.56 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGO54258.1 - 9.8e-05 22.3 0.0 0.0026 17.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 EGO54258.1 - 0.00013 22.5 0.0 0.029 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EGO54258.1 - 0.00014 21.8 0.0 0.74 9.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGO54258.1 - 0.00019 21.7 0.1 0.17 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGO54258.1 - 0.0014 18.3 0.4 0.037 13.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.19 EGO54258.1 - 0.0023 17.6 0.5 0.28 10.8 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EGO54258.1 - 0.0037 17.2 0.2 1.3 8.9 0.1 2.6 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.19 EGO54258.1 - 0.01 15.3 0.0 1.9 7.9 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGO54258.1 - 0.014 15.1 0.2 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGO54258.1 - 0.016 15.7 0.1 1.8 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGO54258.1 - 0.02 15.3 0.0 5 7.5 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CitMHS PF03600.16 EGO54258.1 - 0.046 12.9 8.1 0.024 13.9 2.3 2.9 2 1 0 2 2 2 0 Citrate transporter AAA_24 PF13479.6 EGO54258.1 - 0.056 13.2 0.4 12 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGO54258.1 - 0.084 13.4 0.6 0.23 11.9 0.1 1.9 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 EGO54258.1 - 0.13 12.5 0.1 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EGO54258.1 - 0.13 11.9 0.1 2.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2052 PF09747.9 EGO54260.1 - 0.45 10.6 12.9 0.5 10.5 4.0 2.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) MCU PF04678.13 EGO54260.1 - 5.1 7.2 5.5 2.5 8.1 1.6 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter zf-C3HC4_3 PF13920.6 EGO54260.1 - 5.4 7.0 9.6 1.1 9.2 3.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RPA43_OB PF17875.1 EGO54260.1 - 6.2 7.5 6.7 4.4 8.0 2.4 2.4 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I PAP_assoc PF03828.19 EGO54262.1 - 4e-14 52.6 0.2 7.3e-14 51.7 0.2 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase Actin PF00022.19 EGO54263.1 - 1.1e-112 376.7 0.0 8.3e-112 373.8 0.0 1.9 1 1 0 1 1 1 1 Actin Ldh_2 PF02615.14 EGO54264.1 - 4.8e-121 404.0 1.0 5.4e-121 403.8 1.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Sugar_tr PF00083.24 EGO54265.1 - 8.4e-73 245.7 18.8 1e-72 245.4 18.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO54265.1 - 1.1e-13 50.9 30.7 3.8e-12 45.8 24.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Peptidase_A4 PF01828.17 EGO54267.1 - 2.8e-38 131.5 12.6 3.7e-38 131.1 12.6 1.1 1 0 0 1 1 1 1 Peptidase A4 family FAM86 PF14904.6 EGO54267.1 - 0.086 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function MiAMP1 PF09117.10 EGO54268.1 - 0.038 14.2 0.3 0.095 12.9 0.2 1.7 1 1 0 1 1 1 0 MiAMP1 F-box-like PF12937.7 EGO54269.1 - 0.0012 18.7 0.1 0.0047 16.8 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO54269.1 - 0.042 13.8 1.9 1.8 8.6 0.0 3.6 3 0 0 3 3 3 0 F-box domain MFS_1 PF07690.16 EGO54270.1 - 3.7e-46 157.7 37.4 3.7e-46 157.7 37.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO54270.1 - 1.3e-15 57.2 5.0 1.3e-15 57.2 5.0 3.1 2 1 0 3 3 3 2 Sugar (and other) transporter Glyco_hydro_3_C PF01915.22 EGO54273.1 - 4.1e-45 154.3 0.0 9.6e-45 153.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO54273.1 - 5.2e-39 134.5 0.0 8.7e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGO54273.1 - 1.1e-24 86.3 0.2 2.1e-24 85.4 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Acetyltransf_7 PF13508.7 EGO54276.1 - 3.3e-06 27.4 0.0 2.5e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO54276.1 - 5.5e-05 23.4 0.2 0.00061 20.0 0.2 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO54276.1 - 0.00021 21.2 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGO54276.1 - 0.00036 21.2 0.1 0.0028 18.3 0.0 2.1 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO54276.1 - 0.0011 18.8 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein PutA_N PF18083.1 EGO54277.1 - 0.085 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Proline utilization A N-terminal domain LmjF365940-deam PF14421.6 EGO54278.1 - 0.16 11.5 0.1 0.18 11.4 0.1 1.1 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases DUF948 PF06103.11 EGO54284.1 - 0.13 12.5 2.1 0.26 11.6 0.7 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 EGO54284.1 - 0.74 10.5 3.4 16 6.2 0.5 2.2 1 1 1 2 2 2 0 SlyX DUF4915 PF16261.5 EGO54285.1 - 0.094 11.9 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4915) DUF4762 PF15959.5 EGO54285.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4762) DUF1263 PF06882.12 EGO54286.1 - 0.043 13.9 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1263) Sds3 PF08598.11 EGO54287.1 - 0.88 9.5 8.6 7.2 6.5 0.1 2.4 2 0 0 2 2 2 0 Sds3-like OmpH PF03938.14 EGO54287.1 - 6.4 7.1 10.1 2.2 8.6 7.0 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Pex24p PF06398.11 EGO54289.1 - 1.5e-101 340.1 0.0 2e-101 339.7 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3818 PF12825.7 EGO54292.1 - 6.3e-53 180.0 0.3 1.8e-30 106.1 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EGO54292.1 - 8.6e-39 132.5 0.0 5.3e-38 130.0 0.0 2.3 3 0 0 3 3 3 1 PX-associated MgtE_N PF03448.17 EGO54292.1 - 0.098 13.3 1.2 19 5.9 0.1 2.5 2 0 0 2 2 2 0 MgtE intracellular N domain LID PF17916.1 EGO54292.1 - 0.29 10.8 1.8 0.59 9.8 1.8 1.5 1 0 0 1 1 1 0 LIM interaction domain (LID) Thiolase_N PF00108.23 EGO54295.1 - 2.3e-70 237.0 0.5 2.9e-70 236.6 0.5 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGO54295.1 - 3.4e-42 143.0 0.8 7.7e-41 138.6 0.4 2.5 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGO54295.1 - 0.00096 18.8 0.9 0.003 17.2 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Dynamin_N PF00350.23 EGO54296.1 - 1e-13 51.7 0.0 5.9e-13 49.2 0.0 2.3 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EGO54296.1 - 6.4e-05 23.0 0.0 0.072 13.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran PF00005.27 EGO54296.1 - 0.01 16.3 0.1 0.047 14.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 EGO54296.1 - 0.041 13.8 0.0 0.25 11.2 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Terminase_2 PF03592.16 EGO54296.1 - 3.8 8.0 9.3 20 5.6 2.5 2.8 2 0 0 2 2 2 0 Terminase small subunit DNA_gyraseA_C PF03989.13 EGO54298.1 - 0.074 12.6 0.1 0.099 12.1 0.1 1.2 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller Vint PF14623.6 EGO54299.1 - 1.3e-50 171.5 0.0 2.1e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 EGO54299.1 - 3.8e-31 107.0 0.0 7.3e-31 106.1 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 EGO54299.1 - 1.2e-11 45.2 0.0 4.2e-11 43.4 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EGO54299.1 - 9.8e-11 41.8 0.0 3e-09 37.0 0.0 2.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGO54299.1 - 2.3e-10 41.0 0.0 8.6e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_L13e PF01294.18 EGO54300.1 - 3.8e-74 248.4 1.2 5.1e-74 248.0 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Arm PF00514.23 EGO54301.1 - 0.021 14.8 5.6 27 5.0 0.1 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Ribosomal_L50 PF10501.9 EGO54302.1 - 1.8e-17 63.4 0.1 3.8e-17 62.4 0.1 1.6 1 0 0 1 1 1 1 Ribosomal subunit 39S POM121 PF15229.6 EGO54302.1 - 0.047 13.3 7.5 0.081 12.6 7.5 1.3 1 0 0 1 1 1 0 POM121 family COX14 PF14880.6 EGO54303.1 - 3e-21 75.0 0.1 3e-21 75.0 0.1 2.0 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DAHP_synth_1 PF00793.20 EGO54305.1 - 1.2e-106 355.6 0.1 1.5e-106 355.3 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family CAP_N PF01213.19 EGO54306.1 - 3.5 7.0 13.8 4.6 6.6 13.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 EGO54306.1 - 5.6 7.0 15.7 10 6.2 15.7 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 MFS_1 PF07690.16 EGO54307.1 - 3.6e-27 95.2 51.9 5e-25 88.2 51.4 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO54307.1 - 1.7e-06 27.2 14.1 1.7e-06 27.2 14.1 3.5 2 1 1 3 3 3 1 Sugar (and other) transporter DUF4258 PF14076.6 EGO54307.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) OATP PF03137.20 EGO54307.1 - 5.9 5.1 16.0 0.01 14.1 1.2 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family LRR_8 PF13855.6 EGO54308.1 - 7.7e-35 118.5 50.7 7.9e-08 31.9 0.2 8.4 4 3 2 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 EGO54308.1 - 9.3e-26 89.5 55.3 9.8e-06 25.8 2.5 10.1 4 3 7 12 12 12 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGO54308.1 - 2.8e-10 39.3 40.1 5.9 7.9 2.3 13.5 13 0 0 13 13 13 4 Leucine Rich Repeat LRR_9 PF14580.6 EGO54308.1 - 1.4e-05 24.7 16.3 0.68 9.4 0.1 4.5 2 1 1 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 EGO54308.1 - 3.1e-05 23.7 41.6 2.2 8.5 0.3 11.3 12 0 0 12 12 12 6 Leucine Rich repeat DPM3 PF08285.11 EGO54309.1 - 1.6e-34 118.0 0.6 1.8e-34 117.8 0.6 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Nop14 PF04147.12 EGO54310.1 - 3.8 5.6 9.6 6.8 4.8 9.6 1.3 1 0 0 1 1 1 0 Nop14-like family Pribosyltran PF00156.27 EGO54311.1 - 1.1e-06 28.3 0.0 1.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Oxidored-like PF09791.9 EGO54312.1 - 2.8e-24 84.5 3.3 5.5e-24 83.6 3.3 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal CPDase PF07823.11 EGO54314.1 - 3e-60 203.4 0.0 3.3e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 EGO54314.1 - 0.0071 16.3 0.0 0.41 10.5 0.0 2.4 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily Glyco_trans_4_4 PF13579.6 EGO54316.1 - 0.092 13.2 0.4 6.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain FAA_hydrolase PF01557.18 EGO54317.1 - 2.3e-58 197.4 0.0 3e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EGO54317.1 - 7.4e-33 112.9 0.0 2e-32 111.6 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Fungal_trans PF04082.18 EGO54318.1 - 1.7e-11 43.7 0.0 5e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO54318.1 - 2.3e-08 34.0 9.1 4e-08 33.2 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.10 EGO54318.1 - 0.034 14.5 0.4 0.079 13.3 0.4 1.5 1 0 0 1 1 1 0 HalX domain DUF1194 PF06707.11 EGO54318.1 - 0.046 12.9 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) LPP PF04728.13 EGO54318.1 - 0.44 11.0 2.2 0.41 11.1 0.2 2.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper adh_short PF00106.25 EGO54319.1 - 6.3e-11 42.1 0.0 1.9e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO54319.1 - 0.00062 19.4 0.0 0.0023 17.5 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO54319.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 KR domain NAD_Gly3P_dh_N PF01210.23 EGO54319.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sulfatase PF00884.23 EGO54320.1 - 0.029 13.8 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Sulfatase Trypan_PARP PF05887.11 EGO54321.1 - 0.00071 19.6 4.6 0.00071 19.6 4.6 2.7 2 1 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Chromo PF00385.24 EGO54322.1 - 1.3e-11 44.3 1.6 3.8e-11 42.7 1.6 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 EGO54322.1 - 0.0031 17.6 0.0 0.021 15.0 0.0 2.3 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 DUF3246 PF11596.8 EGO54322.1 - 0.021 14.3 0.8 0.037 13.4 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Apt1 PF10351.9 EGO54322.1 - 2.3 7.0 13.6 2.5 6.9 13.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC27 PF09507.10 EGO54322.1 - 2.3 7.5 42.9 3.3 7.0 42.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ndc1_Nup PF09531.10 EGO54322.1 - 5.6 5.5 11.0 5.9 5.4 11.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3083 PF11281.8 EGO54323.1 - 0.044 13.1 0.0 0.045 13.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) HMGL-like PF00682.19 EGO54326.1 - 7e-80 268.4 0.1 9.4e-80 268.0 0.1 1.2 1 0 0 1 1 1 1 HMGL-like Trp_syntA PF00290.20 EGO54326.1 - 0.076 11.8 0.0 10 4.9 0.0 2.3 2 0 0 2 2 2 0 Tryptophan synthase alpha chain TANGO2 PF05742.12 EGO54327.1 - 5.8e-64 216.6 0.0 8.6e-64 216.0 0.0 1.2 1 1 0 1 1 1 1 Transport and Golgi organisation 2 Tfb2 PF03849.14 EGO54329.1 - 5.6e-116 387.4 0.0 8.2e-108 360.5 0.0 2.1 1 1 1 2 2 2 2 Transcription factor Tfb2 Tfb2_C PF18307.1 EGO54329.1 - 1.6e-22 79.7 1.4 3.1e-22 78.8 1.4 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EGO54329.1 - 0.00034 20.7 0.1 0.0011 19.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PRR18 PF15671.5 EGO54329.1 - 1.1 9.1 5.4 1.8 8.4 5.4 1.2 1 0 0 1 1 1 0 Proline-rich protein family 18 4HBT PF03061.22 EGO54330.1 - 3.1e-13 49.9 0.1 4.5e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily TB2_DP1_HVA22 PF03134.19 EGO54331.1 - 1.5e-26 92.1 10.3 2.3e-26 91.5 10.3 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Nsp1_C PF05064.13 EGO54331.1 - 0.063 13.1 0.2 0.15 11.9 0.0 1.5 2 0 0 2 2 2 0 Nsp1-like C-terminal region MFS_1 PF07690.16 EGO54333.1 - 3e-38 131.6 17.3 2.6e-37 128.6 19.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 EGO54333.1 - 0.0014 18.4 0.3 1.6 8.6 0.1 3.4 2 0 0 2 2 2 2 Lipopolysaccharide assembly protein A domain Cu_amine_oxid PF01179.20 EGO54334.1 - 3.2e-162 540.1 0.0 3.9e-162 539.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EGO54334.1 - 1.9e-21 76.4 0.1 3.5e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EGO54334.1 - 3.1e-13 49.7 0.0 5.5e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CHCH PF06747.13 EGO54335.1 - 0.00013 22.0 6.2 0.00021 21.3 6.2 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EGO54335.1 - 0.051 13.6 0.3 0.72 9.9 0.1 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, BPL_N PF09825.9 EGO54336.1 - 2.3e-125 418.6 0.0 5.3e-125 417.4 0.0 1.5 2 0 0 2 2 2 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EGO54336.1 - 4.5e-23 81.6 0.0 1.1e-22 80.3 0.0 1.7 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 EGO54336.1 - 0.0011 18.9 0.4 0.0021 17.9 0.4 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Pam16 PF03656.13 EGO54338.1 - 2.1e-37 128.0 2.1 2.4e-37 127.8 2.1 1.0 1 0 0 1 1 1 1 Pam16 DUF1682 PF07946.14 EGO54338.1 - 0.044 13.0 1.8 0.052 12.8 1.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1682) Yip1 PF04893.17 EGO54339.1 - 2.7e-07 30.5 14.5 7.2e-06 25.8 7.0 2.5 2 1 0 2 2 2 2 Yip1 domain Phage_holin_3_7 PF05449.11 EGO54339.1 - 1 9.4 3.6 12 6.0 0.1 2.5 3 0 0 3 3 3 0 Putative 3TM holin, Phage_holin_3 RCC1 PF00415.18 EGO54340.1 - 8.6e-60 199.2 1.5 1.6e-07 31.8 0.0 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGO54340.1 - 1.5e-39 133.0 17.6 5.2e-08 32.5 0.2 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat LAT PF15234.6 EGO54340.1 - 1.7 8.3 9.2 1.6 8.4 7.5 1.7 1 1 0 1 1 1 0 Linker for activation of T-cells Methyltransf_16 PF10294.9 EGO54344.1 - 9.2e-29 100.4 0.0 1.4e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EGO54344.1 - 0.11 11.9 0.2 0.23 10.8 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGO54344.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 EGO54344.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain dCMP_cyt_deam_1 PF00383.23 EGO54345.1 - 1.1e-06 28.4 0.0 1.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGO54345.1 - 0.00014 21.6 0.0 0.0019 18.0 0.0 2.1 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EGO54345.1 - 0.085 12.9 0.0 0.2 11.7 0.0 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase DUF3292 PF11696.8 EGO54346.1 - 0.014 13.8 0.0 0.022 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) MID_MedPIWI PF18296.1 EGO54348.1 - 6.1e-06 26.2 3.8 6.1e-06 26.2 3.8 2.0 2 1 0 2 2 1 1 MID domain of medPIWI DUF2076 PF09849.9 EGO54348.1 - 0.017 15.2 25.1 0.017 15.2 25.1 2.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) V_ATPase_I PF01496.19 EGO54348.1 - 0.024 12.6 7.9 0.035 12.0 7.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med15 PF09606.10 EGO54348.1 - 0.04 12.6 25.3 0.076 11.7 25.3 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal WASH-7_C PF14746.6 EGO54348.1 - 0.096 12.4 8.5 0.16 11.6 8.5 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal SpoIIP PF07454.11 EGO54348.1 - 0.11 11.9 10.8 0.2 11.1 10.8 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 EGO54348.1 - 0.12 12.5 7.4 0.24 11.6 7.4 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 EGO54348.1 - 0.13 12.1 13.1 0.52 10.1 10.5 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TMEM214 PF10151.9 EGO54348.1 - 0.14 10.6 10.3 0.21 10.0 10.3 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Phostensin PF13914.6 EGO54348.1 - 0.32 11.6 13.5 0.36 11.5 0.1 3.1 3 0 0 3 3 3 0 Phostensin PP1-binding and SH3-binding region Pex26 PF07163.12 EGO54348.1 - 0.33 10.2 8.8 0.54 9.5 8.8 1.3 1 0 0 1 1 1 0 Pex26 protein Band_3_cyto PF07565.13 EGO54348.1 - 0.38 10.5 8.7 0.8 9.5 8.7 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4175 PF13779.6 EGO54348.1 - 0.41 8.5 29.7 0.59 8.0 29.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) GNAT_acetyltr_2 PF13718.6 EGO54348.1 - 0.42 10.0 8.9 0.75 9.1 8.9 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Serinc PF03348.15 EGO54348.1 - 0.45 9.4 5.8 0.74 8.7 5.8 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) LMBR1 PF04791.16 EGO54348.1 - 0.48 9.3 8.3 0.68 8.8 8.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein UPF0524 PF15823.5 EGO54348.1 - 0.72 9.2 4.3 1.4 8.3 4.3 1.4 1 0 0 1 1 1 0 UPF0524 of C3orf70 DUF2722 PF10846.8 EGO54348.1 - 0.79 8.6 32.0 2 7.3 32.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) AIF_C PF14721.6 EGO54348.1 - 0.8 10.1 11.2 2.1 8.7 11.2 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PAT1 PF09770.9 EGO54348.1 - 0.81 7.9 23.1 0.12 10.6 18.0 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 RPA43_OB PF17875.1 EGO54348.1 - 1.1 9.9 12.0 2.9 8.5 12.0 1.7 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Connexin PF00029.19 EGO54348.1 - 1.1 9.0 8.5 2 8.1 8.5 1.4 1 0 0 1 1 1 0 Connexin ALMT PF11744.8 EGO54348.1 - 1.1 8.0 10.0 1.7 7.4 10.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Plasmodium_Vir PF05795.11 EGO54348.1 - 1.1 8.6 5.8 2.7 7.3 5.8 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Neur_chan_memb PF02932.16 EGO54348.1 - 1.2 9.2 13.8 0.53 10.3 8.9 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SKIP_SNW PF02731.15 EGO54348.1 - 1.3 8.7 19.9 0.39 10.4 0.9 2.4 2 0 0 2 2 2 0 SKIP/SNW domain Tmp39 PF10271.9 EGO54348.1 - 1.3 7.9 7.2 1.9 7.4 7.2 1.1 1 0 0 1 1 1 0 Putative transmembrane protein Hid1 PF12722.7 EGO54348.1 - 1.4 7.0 11.3 2.3 6.2 11.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2126 PF09899.9 EGO54348.1 - 1.4 6.9 10.1 35 2.3 0.0 2.0 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) OATP PF03137.20 EGO54348.1 - 1.5 7.0 6.1 2.1 6.5 6.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family G0-G1_switch_2 PF15103.6 EGO54348.1 - 1.7 9.1 10.8 5.1 7.6 10.8 1.8 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF1764 PF08576.10 EGO54348.1 - 1.9 9.4 15.3 1.2 10.1 12.4 2.2 2 0 0 2 2 1 0 Eukaryotic protein of unknown function (DUF1764) TERB2 PF15101.6 EGO54348.1 - 2.2 8.3 22.6 4.3 7.4 22.6 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 MPM1 PF17234.2 EGO54348.1 - 2.4 8.4 16.8 5.2 7.3 16.8 1.5 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Mgr1 PF08602.10 EGO54348.1 - 2.5 6.8 8.5 4.4 6.0 8.5 1.3 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Peptidase_S49_N PF08496.10 EGO54348.1 - 2.5 8.1 10.2 4.6 7.3 10.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SID-1_RNA_chan PF13965.6 EGO54348.1 - 2.7 6.3 4.1 3.6 5.9 4.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4407 PF14362.6 EGO54348.1 - 3 7.1 15.7 5 6.4 15.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Coilin_N PF15862.5 EGO54348.1 - 3.5 7.4 15.2 9.8 6.0 15.2 1.7 1 0 0 1 1 1 0 Coilin N-terminus DUF2828 PF11443.8 EGO54348.1 - 5.1 5.1 13.1 7.7 4.5 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) FAM60A PF15396.6 EGO54348.1 - 5.5 6.9 12.3 1.2 9.1 8.3 2.0 2 0 0 2 2 2 0 Protein Family FAM60A ACCA PF03255.14 EGO54348.1 - 6 6.7 17.6 0.77 9.6 12.7 1.9 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit CCDC53 PF10152.9 EGO54348.1 - 6.4 7.2 19.9 0.039 14.4 6.2 2.5 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex TFIIA PF03153.13 EGO54348.1 - 7.1 6.5 38.4 0.058 13.4 30.0 1.7 2 1 0 2 2 1 0 Transcription factor IIA, alpha/beta subunit DUF1980 PF09323.10 EGO54348.1 - 7.1 6.5 8.8 15 5.4 8.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) ORC_WH_C PF18137.1 EGO54348.1 - 7.6 6.6 14.4 1.8 8.6 10.6 1.8 2 0 0 2 2 1 0 Origin recognition complex winged helix C-terminal YihI PF04220.12 EGO54353.1 - 0.017 14.8 2.0 0.024 14.4 2.0 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) DUF3439 PF11921.8 EGO54353.1 - 0.022 14.7 0.6 0.035 14.1 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TFIIA PF03153.13 EGO54353.1 - 0.048 13.6 10.3 0.056 13.4 10.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NPR3 PF03666.13 EGO54353.1 - 0.1 11.4 2.0 0.12 11.2 2.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Roughex PF06020.11 EGO54353.1 - 0.15 11.1 3.9 0.55 9.3 4.4 1.6 2 0 0 2 2 2 0 Drosophila roughex protein Spem1 PF15670.5 EGO54353.1 - 0.36 10.4 8.0 0.55 9.8 8.0 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 SelP_N PF04592.14 EGO54353.1 - 0.48 9.8 15.9 0.68 9.3 15.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 EGO54353.1 - 0.8 8.2 2.7 1 7.9 2.7 1.0 1 0 0 1 1 1 0 Macoilin family PAT1 PF09770.9 EGO54353.1 - 5.8 5.1 12.3 6.3 4.9 12.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 EGO54353.1 - 7 5.3 5.9 8.9 5.0 5.9 1.1 1 0 0 1 1 1 0 Presenilin DUF2207 PF09972.9 EGO54355.1 - 0.27 9.9 0.1 0.36 9.6 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CorA PF01544.18 EGO54356.1 - 2.7e-11 43.3 1.3 4.1e-10 39.4 0.0 2.8 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein 7TM-7TMR_HD PF07698.11 EGO54356.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Mif2_N PF15624.6 EGO54358.1 - 6.7 7.4 11.2 13 6.4 11.2 1.6 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Methyltransf_23 PF13489.6 EGO54359.1 - 6.5e-23 81.4 0.0 1e-22 80.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO54359.1 - 8.9e-15 54.8 0.0 4.5e-13 49.3 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO54359.1 - 6.8e-14 52.4 0.0 4.3e-13 49.8 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO54359.1 - 2.7e-12 47.3 0.0 2.1e-11 44.5 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO54359.1 - 7.5e-12 45.7 0.0 2.2e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO54359.1 - 0.00012 21.5 0.0 0.0015 17.9 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EGO54359.1 - 0.0003 21.0 0.0 0.00078 19.6 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 EGO54359.1 - 0.0019 17.5 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EGO54359.1 - 0.0044 16.6 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EGO54359.1 - 0.015 14.8 0.0 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.9 EGO54359.1 - 0.034 13.9 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DRE2_N PF16803.5 EGO54359.1 - 0.054 13.8 0.0 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus CMAS PF02353.20 EGO54359.1 - 0.074 12.3 0.0 0.14 11.5 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 EGO54359.1 - 0.094 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PrmA PF06325.13 EGO54359.1 - 0.16 11.4 0.0 0.3 10.4 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DAO PF01266.24 EGO54360.1 - 5.4e-53 180.8 0.8 6.4e-53 180.6 0.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO54360.1 - 0.0046 17.2 0.3 0.012 15.8 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGO54360.1 - 0.15 12.0 0.1 0.51 10.3 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding HgmA PF04209.13 EGO54361.1 - 1.2e-192 640.3 0.0 1.4e-192 640.1 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase CVNH PF08881.10 EGO54365.1 - 1.7e-25 89.6 0.1 1.9e-25 89.5 0.1 1.0 1 0 0 1 1 1 1 CVNH domain PQQ PF01011.21 EGO54367.1 - 0.034 14.1 0.2 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_3 PF13570.6 EGO54367.1 - 0.045 14.3 0.0 0.22 12.1 0.0 2.3 1 0 0 1 1 1 0 PQQ-like domain ANAPC4_WD40 PF12894.7 EGO54367.1 - 0.11 12.8 0.0 1 9.7 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.16 EGO54368.1 - 4.3e-35 121.3 52.1 4.3e-35 121.3 52.1 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF4510 PF14971.6 EGO54369.1 - 0.0022 18.3 1.1 0.033 14.6 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4510) DUF2046 PF09755.9 EGO54369.1 - 0.0065 15.7 0.5 0.075 12.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Striatin PF08232.12 EGO54369.1 - 0.014 16.0 0.3 0.11 13.1 0.3 2.1 2 0 0 2 2 2 0 Striatin family FlaC_arch PF05377.11 EGO54369.1 - 0.035 14.5 1.8 0.29 11.6 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 EGO54369.1 - 0.099 12.9 0.4 0.23 11.7 0.4 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper RRM_1 PF00076.22 EGO54372.1 - 1.7e-10 40.6 0.0 3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGO54372.1 - 2.9e-05 24.0 0.0 6.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGO54372.1 - 0.032 14.3 0.7 0.066 13.3 0.1 1.8 2 0 0 2 2 2 0 RNA binding motif RRM_occluded PF16842.5 EGO54372.1 - 0.05 13.5 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Cupin_8 PF13621.6 EGO54373.1 - 6.4e-22 78.5 0.0 1.2e-21 77.6 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EGO54373.1 - 0.0082 16.6 0.0 0.16 12.4 0.0 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 EGO54373.1 - 0.0087 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 EGO54373.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Cupin domain DUF5349 PF17298.2 EGO54373.1 - 0.068 12.9 12.2 0.093 12.5 12.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) CK_II_beta PF01214.18 EGO54374.1 - 4.7e-75 251.4 0.0 7.6e-75 250.7 0.0 1.3 1 1 0 1 1 1 1 Casein kinase II regulatory subunit PTPRCAP PF15713.5 EGO54374.1 - 0.014 15.7 9.1 0.85 9.9 4.2 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Spt5_N PF11942.8 EGO54374.1 - 0.037 15.0 4.3 0.037 15.0 4.3 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RRN3 PF05327.11 EGO54374.1 - 0.14 10.7 1.2 0.2 10.1 1.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4611 PF15387.6 EGO54374.1 - 0.87 9.9 9.3 8.8 6.6 4.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 EGO54374.1 - 8.1 5.7 8.3 13 5.0 5.4 2.1 2 0 0 2 2 2 0 NOA36 protein ABC2_membrane PF01061.24 EGO54375.1 - 1.9e-76 256.2 60.7 7.6e-40 136.6 20.5 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGO54375.1 - 1.7e-34 119.3 0.0 3.8e-17 63.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGO54375.1 - 5.3e-25 87.2 12.7 1.8e-24 85.4 0.0 3.5 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EGO54375.1 - 2.1e-18 66.7 0.8 9.1e-18 64.7 0.1 2.5 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_33 PF13671.6 EGO54375.1 - 3.3e-07 30.5 0.0 0.015 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EGO54375.1 - 1.4e-06 28.3 0.0 0.042 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 EGO54375.1 - 1.4e-05 25.5 0.0 0.13 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGO54375.1 - 1.9e-05 25.1 0.0 0.02 15.3 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EGO54375.1 - 2.4e-05 24.9 0.0 0.058 14.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGO54375.1 - 0.00016 21.4 0.3 0.0099 15.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGO54375.1 - 0.00052 20.3 0.0 0.53 10.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EGO54375.1 - 0.00067 19.6 0.1 0.0057 16.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_19 PF13245.6 EGO54375.1 - 0.0047 17.3 0.3 0.22 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EGO54375.1 - 0.0048 16.5 2.3 0.57 9.8 0.5 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 EGO54375.1 - 0.0052 16.2 0.0 0.65 9.4 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EGO54375.1 - 0.0083 16.1 0.6 3.9 7.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 EGO54375.1 - 0.011 16.0 0.1 0.068 13.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGO54375.1 - 0.012 15.4 0.2 1.7 8.3 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGO54375.1 - 0.022 14.3 4.2 0.024 14.2 0.1 2.6 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EGO54375.1 - 0.14 12.6 0.2 61 4.1 0.0 3.6 3 0 0 3 3 3 0 RNA helicase TsaE PF02367.17 EGO54375.1 - 0.18 11.8 1.3 6.3 6.8 0.2 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 EGO54375.1 - 0.38 11.2 0.0 0.38 11.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EGO54375.1 - 2.3 7.9 5.2 17 5.1 0.1 3.3 4 0 0 4 4 4 0 AAA domain DUF1295 PF06966.12 EGO54376.1 - 6.1e-40 137.2 2.1 4.4e-38 131.1 2.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EGO54376.1 - 0.00025 21.0 0.1 0.00052 20.0 0.1 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase MFS_MOT1 PF16983.5 EGO54376.1 - 0.021 15.2 0.0 0.065 13.6 0.0 1.8 1 0 0 1 1 1 0 Molybdate transporter of MFS superfamily GST_N PF02798.20 EGO54376.1 - 0.14 12.6 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain p450 PF00067.22 EGO54377.1 - 3.3e-54 184.4 0.0 4.4e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CATSPERD PF15020.6 EGO54377.1 - 0.17 10.1 0.0 0.27 9.4 0.0 1.2 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta MCPVI PF02993.14 EGO54377.1 - 0.19 11.5 1.2 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 Minor capsid protein VI ScdA_N PF04405.14 EGO54378.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) PEPCK_ATP PF01293.20 EGO54379.1 - 3.9e-218 724.8 0.0 4.6e-218 724.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 EGO54379.1 - 0.032 14.6 0.0 0.052 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EGO54379.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain EF-hand_1 PF00036.32 EGO54382.1 - 1.1e-20 71.6 7.0 4.3e-07 29.0 0.1 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGO54382.1 - 3e-19 69.2 2.5 3.6e-12 46.5 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGO54382.1 - 8.3e-18 62.7 4.2 1.2e-06 28.0 0.2 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 EGO54382.1 - 1.2e-16 60.3 4.5 2.5e-08 33.6 0.2 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGO54382.1 - 3.6e-11 42.0 8.2 9.2e-05 21.8 0.3 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 EGO54382.1 - 9.3e-06 25.9 0.0 0.00035 20.8 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain Caleosin PF05042.13 EGO54382.1 - 0.0012 18.8 0.0 0.35 10.8 0.0 2.1 2 0 0 2 2 2 2 Caleosin related protein EF-hand_4 PF12763.7 EGO54382.1 - 0.0091 15.9 0.2 0.88 9.6 0.1 2.4 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGO54382.1 - 0.022 15.1 0.0 1.8 8.9 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 EGO54382.1 - 0.066 13.3 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Ca2+ insensitive EF hand BUD22 PF09073.10 EGO54383.1 - 4.1e-98 329.6 65.0 6.2e-59 200.5 33.7 2.0 1 1 1 2 2 2 2 BUD22 Sec3_C PF09763.9 EGO54384.1 - 3.1e-270 898.5 0.0 4.1e-270 898.1 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 EGO54384.1 - 2.7e-28 97.9 0.0 4.8e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 EGO54384.1 - 0.0055 17.0 0.6 0.032 14.6 0.0 2.5 2 0 0 2 2 2 1 Sec3 exocyst complex subunit HECT PF00632.25 EGO54387.1 - 1.9e-73 247.6 0.0 3.8e-73 246.7 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 EGO54387.1 - 4.7e-06 26.4 9.8 0.026 14.6 0.1 5.7 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGO54387.1 - 0.0087 16.2 2.6 2.6 8.5 0.1 4.0 3 0 0 3 3 3 2 HEAT repeat CENP-B_dimeris PF09026.10 EGO54387.1 - 0.0092 16.3 13.2 0.0092 16.3 13.2 4.3 3 1 1 4 4 4 1 Centromere protein B dimerisation domain TFIIA PF03153.13 EGO54387.1 - 6.8 6.6 60.5 0.039 13.9 30.5 3.3 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Methyltransf_11 PF08241.12 EGO54388.1 - 8.5e-18 64.8 0.0 1.3e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO54388.1 - 4.7e-16 59.3 0.0 7e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO54388.1 - 9.4e-14 51.5 0.0 1.3e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO54388.1 - 2.8e-12 46.8 0.0 4.5e-12 46.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO54388.1 - 1.2e-11 45.3 0.0 1.6e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO54388.1 - 3.5e-07 29.8 0.0 4.3e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EGO54388.1 - 6.2e-05 23.2 0.0 0.00052 20.2 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 EGO54388.1 - 0.00046 19.2 0.0 0.00062 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 EGO54388.1 - 0.00084 18.9 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGO54388.1 - 0.0076 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EGO54388.1 - 0.02 14.9 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 EGO54388.1 - 0.022 14.7 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 EGO54388.1 - 0.06 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) NNMT_PNMT_TEMT PF01234.17 EGO54388.1 - 0.15 11.2 0.0 12 5.0 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_29 PF03141.16 EGO54388.1 - 0.16 10.5 0.0 12 4.3 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase E1_dh PF00676.20 EGO54389.1 - 9.7e-87 290.7 0.0 1.4e-86 290.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EGO54389.1 - 0.0055 16.5 0.1 0.05 13.4 0.1 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NLBH PF05211.12 EGO54389.1 - 0.013 15.1 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) Tmemb_cc2 PF10267.9 EGO54389.1 - 0.1 11.7 0.4 0.15 11.1 0.4 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CREPT PF16566.5 EGO54389.1 - 0.13 12.4 0.2 0.56 10.4 0.2 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF3106 PF11304.8 EGO54389.1 - 0.16 12.4 4.8 0.29 11.6 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Ubie_methyltran PF01209.18 EGO54391.1 - 1.3e-71 240.7 0.0 4.9e-70 235.5 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGO54391.1 - 8.5e-13 48.8 0.0 8.4e-12 45.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO54391.1 - 2.3e-11 44.2 0.0 3.1e-09 37.4 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO54391.1 - 7.8e-11 42.6 0.0 1.9e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO54391.1 - 2.8e-09 36.9 0.0 4.7e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO54391.1 - 1.1e-06 28.7 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EGO54391.1 - 0.021 14.8 0.0 0.054 13.5 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_8 PF05148.15 EGO54391.1 - 0.025 14.4 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Hypothetical methyltransferase Herpes_TAF50 PF03326.13 EGO54391.1 - 0.028 13.1 0.1 0.042 12.5 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) 2Fe-2S_Ferredox PF11591.8 EGO54391.1 - 0.36 10.7 4.2 0.12 12.2 0.8 2.0 2 0 0 2 2 2 0 Ferredoxin chloroplastic transit peptide DUF2433 PF10360.9 EGO54392.1 - 7.5e-50 168.2 0.0 1.2e-49 167.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 EGO54392.1 - 0.0015 19.1 0.0 0.0032 18.0 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGO54392.1 - 0.022 14.9 0.0 0.073 13.3 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PRCC PF10253.9 EGO54392.1 - 2.4 8.9 11.8 0.35 11.6 7.5 1.8 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting CCDC53 PF10152.9 EGO54392.1 - 3.9 7.9 7.7 20 5.5 7.7 2.1 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Zds_C PF08632.10 EGO54393.1 - 3.9e-31 106.6 0.5 6.7e-31 105.8 0.5 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Peptidase_M43 PF05572.13 EGO54394.1 - 1.7e-10 41.0 0.0 4.4e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EGO54394.1 - 0.00035 20.8 0.1 0.00054 20.2 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EGO54394.1 - 0.0073 16.8 0.5 0.05 14.1 0.5 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pox_polyA_pol_C PF12629.7 EGO54394.1 - 0.015 15.1 0.2 0.021 14.6 0.2 1.2 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase C-terminal domain Reprolysin_4 PF13583.6 EGO54394.1 - 0.019 14.6 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EGO54394.1 - 0.025 14.5 0.0 0.041 13.7 0.0 1.4 1 1 0 1 1 1 0 Matrixin IHHNV_capsid PF16530.5 EGO54394.1 - 0.12 11.4 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Infectious hypodermal and haematopoietic necrosis virus, capsid Amidase PF01425.21 EGO54395.1 - 6.2e-74 249.6 0.0 3.7e-73 247.0 0.0 1.8 1 1 0 1 1 1 1 Amidase CUE PF02845.16 EGO54397.1 - 5.5e-08 32.4 0.0 1.3e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 CUE domain Smr PF01713.21 EGO54397.1 - 0.0015 18.8 0.1 0.0038 17.5 0.1 1.6 1 0 0 1 1 1 1 Smr domain DMA PF03474.14 EGO54397.1 - 0.0025 17.3 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 DMRTA motif NPC1_N PF16414.5 EGO54398.1 - 1.4e-83 280.2 7.1 2.3e-83 279.5 7.1 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 EGO54398.1 - 1.2e-76 258.5 9.1 4.1e-76 256.7 9.2 1.6 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 EGO54398.1 - 5e-50 169.3 7.0 5e-50 169.3 7.0 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EGO54398.1 - 3.9e-07 29.3 29.7 0.00033 19.7 9.2 2.7 2 0 0 2 2 2 2 MMPL family Folate_rec PF03024.14 EGO54398.1 - 9.3e-05 22.4 1.7 0.00021 21.2 1.7 1.5 1 0 0 1 1 1 1 Folate receptor family DUF5392 PF17370.2 EGO54398.1 - 0.16 12.0 0.3 0.91 9.6 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5392) p450 PF00067.22 EGO54399.1 - 2e-63 214.7 0.0 2.7e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aha1_N PF09229.11 EGO54401.1 - 3.6e-41 140.6 0.9 5.7e-41 139.9 0.9 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EGO54401.1 - 7.3e-22 77.9 0.2 1.6e-21 76.8 0.2 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EGO54401.1 - 0.0032 17.8 3.5 0.031 14.5 1.1 2.2 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport CN_hydrolase PF00795.22 EGO54402.1 - 4.3e-22 78.7 0.1 1.7e-21 76.7 0.0 1.9 2 1 0 2 2 2 1 Carbon-nitrogen hydrolase APH PF01636.23 EGO54403.1 - 5.5e-06 26.5 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGO54403.1 - 0.0047 16.5 0.0 0.01 15.5 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase FAD_binding_4 PF01565.23 EGO54404.1 - 2.5e-20 72.6 1.9 3.6e-09 36.5 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.12 EGO54404.1 - 0.038 14.1 0.4 0.11 12.6 0.1 1.9 2 0 0 2 2 2 0 Berberine and berberine like F-box-like PF12937.7 EGO54405.1 - 0.12 12.3 0.0 0.47 10.4 0.0 2.0 1 1 0 1 1 1 0 F-box-like Ashwin PF15323.6 EGO54405.1 - 0.34 10.9 3.8 0.62 10.1 2.1 2.1 2 0 0 2 2 2 0 Developmental protein Complex1_LYR_2 PF13233.6 EGO54407.1 - 3.7e-19 69.3 0.0 4.8e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EGO54407.1 - 0.057 13.5 0.3 0.1 12.7 0.3 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) MMR_HSR1 PF01926.23 EGO54408.1 - 1.1e-17 64.1 0.2 2.3e-17 63.1 0.2 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO54408.1 - 2.3e-10 40.3 0.0 4.7e-10 39.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGO54408.1 - 2.8e-05 24.1 0.2 0.0079 16.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EGO54408.1 - 8.5e-05 22.7 3.4 0.00033 20.8 0.4 2.6 2 1 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 EGO54408.1 - 0.0002 20.9 0.1 0.016 14.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.27 EGO54408.1 - 0.0076 16.8 0.1 0.018 15.5 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EGO54408.1 - 0.031 14.0 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 EGO54408.1 - 0.052 13.3 0.0 0.71 9.6 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TniB PF05621.11 EGO54408.1 - 0.066 12.6 0.1 0.2 11.1 0.0 1.7 3 0 0 3 3 3 0 Bacterial TniB protein AAA_21 PF13304.6 EGO54408.1 - 0.073 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SRPRB PF09439.10 EGO54408.1 - 0.12 11.8 0.1 4.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Septin PF00735.18 EGO54408.1 - 0.19 11.0 0.1 1.1 8.5 0.1 1.9 1 1 0 1 1 1 0 Septin IIGP PF05049.13 EGO54408.1 - 0.21 10.6 0.1 18 4.3 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DHHC PF01529.20 EGO54409.1 - 7.4e-32 110.3 2.9 7.4e-32 110.3 2.9 2.4 3 0 0 3 3 3 1 DHHC palmitoyltransferase Adeno_E3_CR2 PF02439.15 EGO54409.1 - 0.55 10.0 4.1 1.5 8.7 4.1 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Myb_DNA-bind_2 PF08914.11 EGO54410.1 - 2.4e-42 143.0 14.6 1.1e-26 92.8 2.4 2.9 3 0 0 3 3 3 2 Rap1 Myb domain Rap1_C PF11626.8 EGO54410.1 - 4.4e-19 68.3 1.4 1.2e-18 67.0 0.2 2.4 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 EGO54410.1 - 1.8e-10 41.1 0.0 3.8e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain ARID PF01388.21 EGO54410.1 - 3.3e-07 30.9 0.0 1.1e-06 29.2 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Rap1-DNA-bind PF09197.10 EGO54410.1 - 2.6e-05 24.7 10.3 0.0035 17.9 0.2 3.4 3 0 0 3 3 3 2 Rap1, DNA-binding IQ PF00612.27 EGO54410.1 - 0.0042 16.7 3.8 0.0042 16.7 3.8 2.1 2 0 0 2 2 2 1 IQ calmodulin-binding motif DNA_pol_phi PF04931.13 EGO54410.1 - 0.18 9.9 21.4 0.3 9.1 21.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi CEP19 PF14933.6 EGO54410.1 - 0.32 11.3 9.6 1.1 9.6 9.6 1.9 1 0 0 1 1 1 0 CEP19-like protein CDC45 PF02724.14 EGO54410.1 - 1.1 7.5 15.6 2.3 6.4 15.6 1.5 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EGO54410.1 - 1.4 7.3 9.6 2.1 6.8 9.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM60A PF15396.6 EGO54411.1 - 0.11 12.4 7.4 0.27 11.2 7.4 1.5 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.12 EGO54411.1 - 0.19 11.5 21.1 0.47 10.2 21.1 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EGO54411.1 - 4.4 6.0 15.1 9.9 4.8 15.1 1.5 1 0 0 1 1 1 0 Presenilin Fe-ADH PF00465.19 EGO54412.1 - 8.6e-97 324.2 0.2 1.1e-96 323.8 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EGO54412.1 - 6.9e-14 52.2 0.1 2.7e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase FAD_binding_1 PF00667.20 EGO54413.1 - 3.8e-65 219.6 0.1 8.7e-65 218.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain POR PF01558.18 EGO54413.1 - 8.3e-13 48.8 0.1 2.5e-12 47.2 0.1 1.8 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 EGO54413.1 - 7.6e-10 39.4 0.0 4.2e-09 37.0 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 EGO54413.1 - 5.5e-07 29.8 0.4 1.6e-06 28.4 0.4 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II E1-E2_ATPase PF00122.20 EGO54414.1 - 4.4e-50 169.7 3.9 1.2e-49 168.3 0.4 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGO54414.1 - 4.3e-37 128.4 2.3 8.1e-37 127.5 1.4 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGO54414.1 - 1.6e-33 114.9 5.1 8.5e-11 42.1 0.0 5.0 4 1 0 4 4 4 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EGO54414.1 - 8.5e-05 22.4 0.1 0.0006 19.6 0.2 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGO54414.1 - 8.6e-05 23.0 0.0 0.00038 20.9 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Importin_rep_3 PF18806.1 EGO54414.1 - 0.0028 17.6 0.0 0.0075 16.3 0.0 1.7 1 0 0 1 1 1 1 Importin 13 repeat BCLP PF12304.8 EGO54414.1 - 0.01 15.4 0.8 0.023 14.3 0.1 1.9 2 0 0 2 2 2 0 Beta-casein like protein zf-C3HC PF07967.13 EGO54415.1 - 3.3e-43 146.9 0.2 1.4e-38 131.9 0.1 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 EGO54415.1 - 1.4e-30 105.3 0.6 1.2e-29 102.3 0.0 2.4 2 1 0 2 2 2 1 Rsm1-like BIR PF00653.21 EGO54415.1 - 0.00063 20.3 0.2 0.014 16.0 0.2 2.5 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain zf-RING_4 PF14570.6 EGO54416.1 - 1.5e-15 56.7 9.5 3.1e-15 55.7 9.5 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 EGO54416.1 - 2.4e-10 40.1 0.0 7.8e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.12 EGO54416.1 - 3.5e-05 23.3 2.8 3.5e-05 23.3 2.8 3.8 3 1 0 3 3 2 1 Rtf2 RING-finger zf-C3HC4_3 PF13920.6 EGO54416.1 - 0.00017 21.3 4.5 0.00017 21.3 4.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO54416.1 - 0.0028 17.9 7.8 0.0028 17.9 7.8 2.2 2 0 0 2 2 2 1 Ring finger domain SET_assoc PF11767.8 EGO54416.1 - 0.0035 16.9 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.6 EGO54416.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF3106 PF11304.8 EGO54416.1 - 0.038 14.4 3.9 7.5 7.1 1.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) FYVE PF01363.21 EGO54416.1 - 0.77 9.9 4.0 1.1 9.5 2.5 1.9 2 0 0 2 2 2 0 FYVE zinc finger zf-RING_UBOX PF13445.6 EGO54416.1 - 1.6 8.8 4.7 2 8.5 3.2 2.0 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGO54416.1 - 4.1 7.3 6.7 11 6.0 6.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Complex1_30kDa PF00329.19 EGO54417.1 - 4.3e-45 153.3 0.0 5.9e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Dioxygenase_C PF00775.21 EGO54418.1 - 1.6e-42 145.0 0.0 2.1e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EGO54418.1 - 8.1e-24 83.3 0.2 1.5e-23 82.4 0.2 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EGO54418.1 - 0.0085 16.3 0.0 0.048 13.9 0.0 2.3 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 EGO54418.1 - 0.034 14.5 0.0 0.067 13.5 0.0 1.4 1 0 0 1 1 1 0 Prealbumin-like fold domain Lactonase PF10282.9 EGO54420.1 - 1.2e-15 57.7 0.0 1.6e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SKG6 PF08693.10 EGO54421.1 - 1.3e-06 27.7 0.2 3.2e-06 26.4 0.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 EGO54421.1 - 8.3e-05 22.7 2.5 0.00012 22.2 2.5 1.1 1 0 0 1 1 1 1 Podoplanin DUF4448 PF14610.6 EGO54421.1 - 0.066 13.0 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) BacteriocIIc_cy PF12173.8 EGO54421.1 - 0.56 10.5 3.0 0.6 10.4 1.1 2.0 1 1 1 2 2 2 0 Bacteriocin class IIc cyclic gassericin A-like Inositol_P PF00459.25 EGO54422.1 - 1.1e-45 156.2 0.7 1.5e-45 155.8 0.7 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.23 EGO54423.1 - 0.0026 18.4 0.0 0.011 16.4 0.0 2.0 1 1 1 2 2 2 1 Ribosomal protein L6 Tht1 PF04163.12 EGO54424.1 - 2.2e-06 26.7 2.6 5.4e-06 25.5 2.1 1.9 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein Zw10 PF06248.13 EGO54424.1 - 0.0011 17.6 3.5 0.0011 17.6 3.5 1.6 1 1 1 2 2 2 1 Centromere/kinetochore Zw10 Fmp27_WPPW PF10359.9 EGO54424.1 - 0.01 14.7 8.0 0.032 13.1 1.7 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Alb1 PF09135.11 EGO54424.1 - 0.037 14.9 0.8 0.071 14.0 0.1 1.8 2 0 0 2 2 1 0 Alb1 DUF4709 PF15821.5 EGO54424.1 - 0.14 12.5 4.3 0.28 11.5 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4709) DUF3450 PF11932.8 EGO54424.1 - 0.14 11.4 21.0 0.052 12.8 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) GAS PF13851.6 EGO54424.1 - 0.46 9.8 16.8 0.11 11.8 1.8 2.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2884 PF11101.8 EGO54424.1 - 1.2 8.6 12.1 0.072 12.6 1.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) Noelin-1 PF12308.8 EGO54424.1 - 3.1 7.9 7.3 0.54 10.3 1.4 2.4 2 1 0 2 2 2 0 Neurogenesis glycoprotein Spc7 PF08317.11 EGO54424.1 - 5.3 5.8 19.7 1.5 7.7 5.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DASH_Dad2 PF08654.10 EGO54424.1 - 6.5 7.2 8.8 1.9 8.9 2.3 2.9 1 1 0 2 2 2 0 DASH complex subunit Dad2 YscO PF07321.12 EGO54424.1 - 7.6 6.5 17.2 0.11 12.5 7.1 2.5 2 1 0 2 2 2 0 Type III secretion protein YscO Prefoldin_2 PF01920.20 EGO54424.1 - 8.7 6.4 14.8 0.21 11.6 0.3 3.7 2 2 3 5 5 5 0 Prefoldin subunit YabA PF06156.13 EGO54424.1 - 8.7 7.0 9.6 12 6.6 3.2 2.5 2 0 0 2 2 2 0 Initiation control protein YabA Prominin PF05478.11 EGO54424.1 - 9 4.1 11.0 1.1 7.2 2.1 1.9 1 1 0 1 1 1 0 Prominin DUF1664 PF07889.12 EGO54424.1 - 9.5 6.3 9.2 2.7 8.1 0.9 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) SGL PF08450.12 EGO54425.1 - 0.042 13.4 0.5 9 5.8 0.0 2.2 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Ion_trans_2 PF07885.16 EGO54426.1 - 1.7e-31 108.0 19.5 2.3e-18 65.9 3.7 2.9 4 0 0 4 4 4 2 Ion channel Tox-HNH-EHHH PF15657.6 EGO54426.1 - 0.0037 17.6 0.0 0.013 15.8 0.0 1.9 2 0 0 2 2 2 1 HNH/Endo VII superfamily nuclease toxins Ion_trans PF00520.31 EGO54426.1 - 0.0044 16.3 14.1 0.034 13.4 0.3 2.6 2 1 0 2 2 2 2 Ion transport protein WD40 PF00400.32 EGO54428.1 - 4.8e-22 77.9 21.8 2.8e-05 24.8 0.1 6.8 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO54428.1 - 1.3e-11 44.7 7.8 6.6e-06 26.3 0.2 4.2 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 EGO54428.1 - 0.00012 22.0 9.4 0.022 14.7 0.2 3.4 1 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 EGO54428.1 - 0.016 14.2 0.6 1 8.3 0.0 3.3 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein YmzC PF14157.6 EGO54428.1 - 0.12 12.4 0.0 1.9 8.7 0.0 2.8 4 0 0 4 4 4 0 YmzC-like protein IKI3 PF04762.12 EGO54428.1 - 1.5 6.7 3.8 7.3 4.4 0.1 2.1 2 0 0 2 2 2 0 IKI3 family DUF4407 PF14362.6 EGO54429.1 - 0.2 11.0 7.0 0.28 10.5 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) End3 PF12761.7 EGO54429.1 - 0.45 10.7 7.2 0.72 10.0 7.2 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 SIR4_SID PF16991.5 EGO54429.1 - 0.63 10.1 2.9 1.2 9.2 2.9 1.4 1 0 0 1 1 1 0 Sir4 SID domain DUF5320 PF17253.2 EGO54429.1 - 5 8.2 10.9 4.7 8.4 7.5 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DOPA_dioxygen PF08883.11 EGO54431.1 - 1.1e-39 135.0 0.1 1.4e-39 134.6 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Podoplanin PF05808.11 EGO54432.1 - 0.00015 21.9 0.3 0.00027 21.1 0.3 1.4 1 0 0 1 1 1 1 Podoplanin EphA2_TM PF14575.6 EGO54432.1 - 0.01 16.7 0.0 0.026 15.4 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF1180 PF06679.12 EGO54432.1 - 0.028 14.8 0.6 0.028 14.8 0.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) SKG6 PF08693.10 EGO54432.1 - 0.086 12.3 0.7 0.18 11.2 0.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LapA_dom PF06305.11 EGO54432.1 - 0.19 11.6 0.2 0.35 10.7 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain bZIP_1 PF00170.21 EGO54433.1 - 0.00081 19.4 7.9 0.0016 18.5 7.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGO54433.1 - 0.0043 17.1 6.4 0.0077 16.3 6.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Pex14_N PF04695.13 EGO54433.1 - 0.25 12.0 13.9 0.3 11.7 8.6 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.10 EGO54433.1 - 4.4 5.9 8.2 5.3 5.6 8.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tubulin PF00091.25 EGO54435.1 - 1.9e-68 230.5 0.0 4.7e-68 229.3 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGO54435.1 - 5.5e-43 146.1 0.1 8.3e-43 145.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGO54435.1 - 3.1e-05 24.3 0.0 7.8e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EGO54435.1 - 0.0021 17.3 0.0 0.024 13.8 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 EGO54435.1 - 0.0026 17.4 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain ABC_tran PF00005.27 EGO54437.1 - 1.3e-48 165.0 0.3 1e-22 81.1 0.0 3.2 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EGO54437.1 - 8.3e-21 73.8 5.0 8.3e-21 73.8 5.0 4.2 3 1 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 EGO54437.1 - 4.6e-15 56.2 8.2 0.00081 19.3 0.0 4.4 2 2 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGO54437.1 - 7.2e-12 45.2 0.4 0.008 15.6 0.0 4.5 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EGO54437.1 - 1.6e-07 32.0 0.2 0.014 15.9 0.0 3.6 3 1 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 EGO54437.1 - 6.9e-07 29.3 0.9 0.0084 16.2 0.1 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EGO54437.1 - 1.6e-06 27.7 0.1 0.051 13.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 EGO54437.1 - 5.7e-06 26.2 3.3 0.0072 16.1 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.6 EGO54437.1 - 1.2e-05 25.6 0.1 0.026 14.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EGO54437.1 - 1.7e-05 25.4 0.2 0.0054 17.3 0.0 4.5 5 0 0 5 5 4 2 AAA domain AAA_22 PF13401.6 EGO54437.1 - 2e-05 24.9 0.0 0.11 12.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGO54437.1 - 2.3e-05 24.8 0.3 0.046 14.1 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGO54437.1 - 2.9e-05 24.1 0.5 0.076 12.9 0.0 2.9 2 1 0 3 3 3 2 RsgA GTPase AAA_27 PF13514.6 EGO54437.1 - 7.4e-05 22.4 0.4 4.4 6.8 0.0 4.1 4 1 0 4 4 3 0 AAA domain AAA PF00004.29 EGO54437.1 - 0.00019 21.9 0.1 0.45 10.9 0.2 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGO54437.1 - 0.00019 21.6 3.5 0.13 12.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 EGO54437.1 - 0.00025 20.8 1.2 1 9.0 0.1 3.4 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 EGO54437.1 - 0.0016 18.2 15.4 0.087 12.5 0.0 4.7 4 1 1 5 5 5 2 AAA ATPase domain AAA_14 PF13173.6 EGO54437.1 - 0.0017 18.4 0.1 4.4 7.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 EGO54437.1 - 0.0042 17.2 3.2 3.6 7.6 0.0 3.9 4 0 0 4 4 4 1 Dynamin family Roc PF08477.13 EGO54437.1 - 0.0045 17.2 0.2 3.7 7.8 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 EGO54437.1 - 0.0067 15.4 1.6 0.93 8.4 0.0 2.7 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EGO54437.1 - 0.0073 16.2 0.1 0.83 9.5 0.1 2.7 2 0 0 2 2 2 1 NTPase AAA_7 PF12775.7 EGO54437.1 - 0.0079 15.7 0.1 4 6.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 EGO54437.1 - 0.0082 16.1 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 EGO54437.1 - 0.0083 15.7 0.6 2.6 7.6 0.6 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EGO54437.1 - 0.0085 16.0 0.8 4.3 7.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_5 PF07728.14 EGO54437.1 - 0.016 15.2 0.2 6.4 6.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 EGO54437.1 - 0.017 14.8 0.1 0.66 9.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 EGO54437.1 - 0.019 15.4 0.0 9.7 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 EGO54437.1 - 0.019 14.2 0.1 3.3 6.8 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 EGO54437.1 - 0.037 14.0 0.8 6.4 6.7 0.0 3.2 3 0 0 3 3 3 0 Rad17 P-loop domain Zeta_toxin PF06414.12 EGO54437.1 - 0.043 13.1 1.1 2.8 7.2 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin MobB PF03205.14 EGO54437.1 - 0.048 13.6 0.3 1.3 8.9 0.2 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 EGO54437.1 - 0.052 13.2 1.3 3.6 7.2 0.0 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.17 EGO54437.1 - 0.056 13.1 0.2 1.6 8.3 0.0 3.1 3 0 0 3 3 2 0 Thymidylate kinase Arf PF00025.21 EGO54437.1 - 0.095 12.1 0.1 1.5 8.3 0.1 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family ATP_bind_1 PF03029.17 EGO54437.1 - 0.3 10.8 1.3 31 4.2 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.21 EGO54437.1 - 0.36 10.2 1.9 49 3.2 0.2 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 EGO54437.1 - 0.68 10.4 9.2 10 6.5 0.3 4.0 4 1 0 4 4 3 0 AAA domain DUF87 PF01935.17 EGO54437.1 - 3.7 7.6 9.6 2.5 8.1 0.1 3.6 4 0 0 4 4 4 0 Helicase HerA, central domain bZIP_1 PF00170.21 EGO54438.1 - 0.0001 22.3 7.1 0.00017 21.6 7.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGO54438.1 - 0.00013 21.9 8.6 0.00026 21.0 8.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EGO54438.1 - 0.091 13.3 1.3 0.091 13.3 1.3 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor Fes1 PF08609.10 EGO54438.1 - 0.35 11.8 4.6 2.4 9.1 4.6 2.2 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 MIS13 PF08202.11 EGO54438.1 - 2.5 7.3 6.8 0.88 8.8 0.3 2.2 2 0 0 2 2 2 0 Mis12-Mtw1 protein family A_deaminase PF00962.22 EGO54440.1 - 4e-25 88.8 0.1 7.3e-24 84.7 0.1 2.2 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 EGO54440.1 - 0.03 14.6 0.0 0.096 13.0 0.0 1.9 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal Ubiquitin_4 PF18036.1 EGO54440.1 - 0.045 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain SRP40_C PF05022.12 EGO54441.1 - 6.4e-25 87.8 0.5 6.4e-25 87.8 0.5 3.0 2 1 0 2 2 2 1 SRP40, C-terminal domain DUF2207 PF09972.9 EGO54443.1 - 0.16 10.7 3.8 3 6.5 0.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Complex1_51K PF01512.17 EGO54445.1 - 6.5e-47 159.2 0.0 1e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EGO54445.1 - 2.3e-29 101.3 1.5 2.9e-29 100.9 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EGO54445.1 - 5.6e-09 35.7 0.0 2.6e-08 33.6 0.0 2.2 3 0 0 3 3 3 1 SLBB domain Hexapep PF00132.24 EGO54447.1 - 6.3e-09 35.2 11.9 2.1e-05 24.0 4.2 3.9 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGO54447.1 - 0.035 13.9 10.7 4.6 7.1 0.0 3.9 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase PFL-like PF02901.15 EGO54447.1 - 0.24 10.0 0.0 0.32 9.6 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase-like Flavoprotein PF02441.19 EGO54448.1 - 2.4e-18 66.4 0.0 3.6e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.6 EGO54448.1 - 0.00052 20.5 0.0 0.39 11.4 0.0 3.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) DEAD PF00270.29 EGO54450.1 - 7.1e-41 139.9 0.1 1.5e-40 138.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO54450.1 - 2.1e-26 92.5 0.2 3.3e-25 88.6 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain eIF3_subunit PF08597.10 EGO54450.1 - 0.0065 16.4 28.7 0.0065 16.4 28.7 4.0 5 0 0 5 5 5 1 Translation initiation factor eIF3 subunit CDC45 PF02724.14 EGO54450.1 - 0.19 10.0 37.4 0.052 11.8 8.9 2.7 3 0 0 3 3 3 0 CDC45-like protein GREB1 PF15782.5 EGO54450.1 - 2 5.4 18.1 0.025 11.7 5.3 2.1 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer SpoIIP PF07454.11 EGO54450.1 - 2.7 7.4 25.1 4 6.8 11.4 2.6 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2052 PF09747.9 EGO54450.1 - 5.1 7.2 49.2 0.88 9.7 0.8 3.6 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) TCP PF03634.13 EGO54450.1 - 6.5 7.3 23.7 0.14 12.8 9.0 3.3 3 0 0 3 3 3 0 TCP family transcription factor Velvet PF11754.8 EGO54450.1 - 7.5 6.4 10.2 5.5 6.8 5.2 2.4 2 0 0 2 2 2 0 Velvet factor SOBP PF15279.6 EGO54450.1 - 9.8 6.7 14.1 4.8 7.7 9.0 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein FtsJ PF01728.19 EGO54451.1 - 1.6e-63 214.0 0.0 2.1e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Gly_transf_sug PF04488.15 EGO54453.1 - 6.1e-09 36.4 0.0 1.2e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EGO54453.1 - 0.00097 18.6 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 EGO54453.1 - 0.0048 16.3 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Glyco_transf_15 PF01793.16 EGO54454.1 - 3.7e-93 312.3 5.3 6.1e-93 311.6 5.3 1.3 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4175 PF13779.6 EGO54454.1 - 0.12 10.2 0.1 0.16 9.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SLY PF12485.8 EGO54455.1 - 0.057 14.1 7.1 0.074 13.8 7.1 1.1 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Mitofilin PF09731.9 EGO54455.1 - 7.7 5.2 20.2 8.2 5.1 20.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hira PF07569.11 EGO54456.1 - 1.1e-84 283.6 0.1 4.1e-84 281.7 0.0 2.1 3 0 0 3 3 3 1 TUP1-like enhancer of split WD40 PF00400.32 EGO54456.1 - 8.9e-31 105.5 21.6 1.2e-05 25.9 0.1 8.7 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO54456.1 - 6e-17 61.7 0.1 0.031 14.6 0.1 6.4 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EGO54456.1 - 8.8e-12 44.6 0.8 2.2e-11 43.3 0.8 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 EGO54456.1 - 9.9e-06 25.4 1.3 15 5.7 0.0 5.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EGO54456.1 - 4.3e-05 22.6 0.5 0.073 12.0 0.0 4.4 4 1 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGO54456.1 - 0.00049 20.0 0.3 1.8 8.4 0.0 4.0 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 EGO54456.1 - 0.045 13.1 0.1 4.2 6.6 0.0 2.7 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 EGO54456.1 - 0.14 10.8 0.0 0.79 8.3 0.0 2.2 4 0 0 4 4 4 0 Nucleoporin Nup120/160 MARVEL PF01284.23 EGO54458.1 - 1.4e-09 38.1 6.4 5.6e-09 36.2 6.3 1.8 2 0 0 2 2 2 1 Membrane-associating domain DUF588 PF04535.12 EGO54458.1 - 0.00045 20.0 1.8 0.00084 19.1 1.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF588) DUF5518 PF17647.1 EGO54458.1 - 2.5 8.3 11.0 0.23 11.6 5.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5518) PIR PF00399.19 EGO54459.1 - 0.0034 16.9 7.3 0.4 10.3 0.1 2.9 2 0 0 2 2 2 2 Yeast PIR protein repeat zf-U1 PF06220.12 EGO54460.1 - 4.6e-09 35.9 0.2 7.5e-09 35.2 0.2 1.4 1 0 0 1 1 1 1 U1 zinc finger Glyco_trans_1_4 PF13692.6 EGO54462.1 - 3.8e-11 43.6 0.0 8.6e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGO54462.1 - 1.8e-10 40.7 0.0 7.6e-10 38.6 0.0 2.0 2 1 0 2 2 2 1 Glycosyl transferases group 1 CENP-H PF05837.12 EGO54463.1 - 0.013 15.9 2.7 0.013 15.9 2.7 3.9 3 1 1 4 4 4 0 Centromere protein H (CENP-H) SR-25 PF10500.9 EGO54463.1 - 8.7 5.9 39.1 1.1 8.9 17.0 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Glyco_hydro_7 PF00840.20 EGO54464.1 - 4.2e-85 286.1 0.3 8.4e-46 156.6 0.0 3.0 1 1 2 3 3 3 3 Glycosyl hydrolase family 7 Flavi_NS4A PF01350.17 EGO54466.1 - 0.22 11.5 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A HECT PF00632.25 EGO54468.1 - 2.3e-61 208.0 0.0 5e-61 206.9 0.0 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 EGO54468.1 - 4.1e-22 78.2 2.5 1e-21 76.9 2.5 1.7 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-C2H2_2 PF12756.7 EGO54469.1 - 2.4e-37 127.3 5.8 8.2e-29 99.9 0.4 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EGO54469.1 - 5e-12 45.8 12.0 2.5e-07 30.8 5.5 3.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGO54469.1 - 1.3e-06 28.6 9.3 9.5e-06 25.8 4.0 3.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EGO54469.1 - 7.2e-05 23.0 17.2 0.74 10.4 0.3 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type SnoaL_2 PF12680.7 EGO54469.1 - 0.029 15.0 0.0 0.49 11.1 0.0 2.7 2 1 1 3 3 3 0 SnoaL-like domain DUF629 PF04780.12 EGO54469.1 - 0.14 10.7 1.4 0.73 8.3 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-3CxxC_2 PF17180.4 EGO54469.1 - 4.1 8.2 5.9 3.4 8.5 0.8 3.0 3 0 0 3 3 3 0 Zinc-binding domain zf-C2HE PF16278.5 EGO54469.1 - 4.1 7.9 5.0 2.8 8.5 0.0 3.2 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger ABC_tran PF00005.27 EGO54470.1 - 3e-46 157.3 0.2 5.1e-25 88.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EGO54470.1 - 8e-28 97.5 42.1 1.8e-18 66.8 22.8 2.5 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 EGO54470.1 - 8.6e-23 81.6 2.3 1.4e-05 25.1 0.0 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 EGO54470.1 - 1.5e-07 32.1 0.1 0.0037 18.0 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4162) AAA_29 PF13555.6 EGO54470.1 - 1.6e-07 30.9 0.9 0.0095 15.7 0.3 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 EGO54470.1 - 3.6e-06 26.6 2.9 1.5 8.2 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGO54470.1 - 3.1e-05 24.6 3.1 0.13 12.8 0.5 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EGO54470.1 - 0.00056 19.7 0.1 0.69 9.6 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGO54470.1 - 0.0036 17.2 3.3 1.2 9.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Rad17 PF03215.15 EGO54470.1 - 0.0082 16.1 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 EGO54470.1 - 0.0087 16.5 0.2 3.6 7.9 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EGO54470.1 - 0.015 15.1 3.8 3.1 7.5 0.0 3.3 3 1 0 3 3 3 0 AAA domain AAA_27 PF13514.6 EGO54470.1 - 0.021 14.5 0.2 5.4 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGO54470.1 - 0.026 14.9 0.7 1.1 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EGO54470.1 - 0.06 13.6 0.5 36 4.7 0.1 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 EGO54470.1 - 0.071 13.4 0.3 8.7 6.6 0.2 2.7 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 EGO54470.1 - 0.13 12.1 0.7 7.7 6.3 0.1 2.5 2 0 0 2 2 2 0 MukB N-terminal SRP54 PF00448.22 EGO54470.1 - 0.2 11.3 1.8 13 5.3 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EGO54470.1 - 0.97 9.8 3.6 43 4.4 0.1 3.4 3 0 0 3 3 3 0 AAA domain tRNA-synt_2 PF00152.20 EGO54471.1 - 2.8e-73 246.7 0.7 3.7e-73 246.3 0.7 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGO54471.1 - 1.3e-11 44.3 0.0 2.5e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGO54471.1 - 9.2e-10 38.4 0.2 6.1e-05 22.6 0.1 2.9 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) CTP_transf_like PF01467.26 EGO54472.1 - 8.3e-21 74.7 0.0 1.3e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Chibby PF14645.6 EGO54474.1 - 0.0038 17.6 2.1 0.01 16.2 2.1 1.7 1 0 0 1 1 1 1 Chibby family zf-C2H2_4 PF13894.6 EGO54474.1 - 0.016 16.0 0.4 0.061 14.2 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO54474.1 - 0.096 13.2 0.1 0.24 11.9 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Molybdopterin_N PF18364.1 EGO54474.1 - 0.72 9.9 3.1 0.62 10.1 0.2 2.4 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain YabA PF06156.13 EGO54474.1 - 1.6 9.4 4.1 0.92 10.2 1.7 1.8 2 0 0 2 2 2 0 Initiation control protein YabA Chromo_shadow PF01393.19 EGO54475.1 - 2e-19 69.4 1.7 1.6e-16 60.1 0.3 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 EGO54475.1 - 1.8e-13 50.2 0.8 1.8e-13 50.2 0.8 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4944 PF16302.5 EGO54475.1 - 0.018 15.1 0.0 0.018 15.1 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4944) AT_hook PF02178.19 EGO54475.1 - 0.085 12.8 0.4 0.24 11.4 0.4 1.8 1 0 0 1 1 1 0 AT hook motif Myc_N PF01056.18 EGO54475.1 - 1.1 9.1 10.9 11 5.8 6.2 2.2 2 0 0 2 2 2 0 Myc amino-terminal region His_Phos_1 PF00300.22 EGO54477.1 - 1.5e-14 54.1 5.2 4e-11 43.0 1.5 3.9 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) VHS PF00790.19 EGO54478.1 - 1e-42 145.3 1.1 1.9e-41 141.2 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 EGO54478.1 - 1.2e-14 54.2 5.2 2.4e-14 53.2 5.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EGO54478.1 - 4e-06 26.4 18.4 0.00058 19.6 2.1 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.14 EGO54478.1 - 0.00016 21.9 0.0 0.00047 20.4 0.0 1.9 1 0 0 1 1 1 1 GAT domain FYVE_2 PF02318.16 EGO54478.1 - 0.068 13.4 1.9 0.23 11.7 1.9 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Fer4_2 PF12797.7 EGO54478.1 - 1.9 8.8 8.3 2.4 8.4 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain UCH PF00443.29 EGO54479.1 - 1.9e-33 116.1 0.0 2.9e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO54479.1 - 6.5e-10 39.1 0.0 1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 EGO54479.1 - 8e-06 26.3 0.0 1.7e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain USP8_dimer PF08969.11 EGO54479.1 - 0.0028 17.8 0.0 0.0067 16.6 0.0 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain Aldedh PF00171.22 EGO54480.1 - 2.1e-83 280.4 0.0 2.6e-83 280.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_transf_90 PF05686.12 EGO54481.1 - 3.5e-16 59.1 0.0 3.2e-13 49.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 zf-ZPR1 PF03367.13 EGO54481.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Acyl_transf_1 PF00698.21 EGO54482.1 - 7.1e-18 65.2 0.1 5.8e-12 45.8 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain DUF2458 PF10454.9 EGO54482.1 - 0.13 11.9 0.2 0.24 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) ECR1_N PF14382.6 EGO54483.1 - 3.6e-16 58.7 0.3 7.4e-16 57.7 0.3 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EGO54483.1 - 6.4e-06 26.4 0.2 1.3e-05 25.5 0.2 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 EGO54483.1 - 0.069 13.8 0.2 1.4 9.6 0.1 2.5 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 S1 PF00575.23 EGO54483.1 - 0.19 12.1 1.2 26 5.2 0.0 2.9 3 0 0 3 3 3 0 S1 RNA binding domain AFG1_ATPase PF03969.16 EGO54484.1 - 1.1e-55 189.0 0.1 3.1e-25 88.9 0.0 5.0 3 2 2 5 5 5 4 AFG1-like ATPase AAA_5 PF07728.14 EGO54484.1 - 1.8e-05 24.7 0.0 4.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO54484.1 - 0.00035 21.0 0.6 0.011 16.1 0.0 2.9 1 1 2 3 3 3 1 AAA ATPase domain AAA PF00004.29 EGO54484.1 - 0.001 19.5 0.0 0.002 18.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO54484.1 - 0.0017 18.7 0.2 0.011 16.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGO54484.1 - 0.0056 17.2 0.2 4.6 7.7 0.1 2.6 1 1 1 2 2 2 2 ABC transporter AAA_29 PF13555.6 EGO54484.1 - 0.034 13.9 0.0 0.096 12.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EGO54484.1 - 0.11 11.9 0.3 0.66 9.5 0.0 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region NACHT PF05729.12 EGO54484.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain PIF1 PF05970.14 EGO54484.1 - 0.24 10.5 0.0 0.43 9.7 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase DUF4617 PF15395.6 EGO54484.1 - 0.27 9.5 0.1 0.4 8.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4617) Nucleoporin_C PF03177.14 EGO54485.1 - 3.3e-175 584.2 8.9 4e-175 584.0 8.9 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EGO54485.1 - 2e-92 310.2 0.0 2.6e-92 309.8 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.25 EGO54487.1 - 6.4e-28 97.8 0.0 8.3e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO54487.1 - 9e-15 54.7 0.0 1.8e-14 53.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO54487.1 - 4.8e-07 28.9 0.0 8.1e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase EMP24_GP25L PF01105.24 EGO54488.1 - 4e-52 176.8 0.0 4.6e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SANT_DAMP1_like PF16282.5 EGO54489.1 - 2.3e-32 111.0 0.2 4e-32 110.2 0.2 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Hexapep PF00132.24 EGO54491.1 - 3.2e-13 48.8 16.3 1.4e-08 34.1 2.4 3.5 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 EGO54491.1 - 1e-11 44.9 0.0 2.3e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.18 EGO54491.1 - 4.2e-09 36.4 10.3 8.3e-09 35.4 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.6 EGO54491.1 - 4.3e-09 36.0 16.3 6.4e-05 22.6 1.5 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF2722 PF10846.8 EGO54492.1 - 0.0013 17.7 2.2 0.0015 17.6 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 EGO54492.1 - 0.0018 18.0 3.9 0.0018 18.0 3.9 1.1 1 0 0 1 1 1 1 Spt20 family Roughex PF06020.11 EGO54492.1 - 0.0086 15.2 2.2 0.0091 15.1 2.2 1.1 1 0 0 1 1 1 1 Drosophila roughex protein Adap_comp_sub PF00928.21 EGO54493.1 - 1.3e-86 290.3 0.0 1.5e-86 290.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGO54493.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4536 PF15055.6 EGO54494.1 - 2.2e-07 31.0 0.2 4.1e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) Coiled-coil_56 PF09813.9 EGO54494.1 - 0.029 14.4 0.1 3.2 7.9 0.0 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 Sel_put PF04328.13 EGO54494.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Selenoprotein, putative Glyco_hydro_6 PF01341.17 EGO54496.1 - 1.5e-99 333.6 0.2 1.9e-99 333.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 OST3_OST6 PF04756.13 EGO54497.1 - 2.1e-107 358.9 0.0 2.4e-107 358.7 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF4535 PF15054.6 EGO54497.1 - 0.0016 18.1 0.2 0.0033 17.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4535) Thioredoxin PF00085.20 EGO54497.1 - 0.08 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin MerC PF03203.14 EGO54497.1 - 0.13 12.8 3.5 0.53 10.7 0.4 2.5 2 0 0 2 2 2 0 MerC mercury resistance protein VKOR PF07884.14 EGO54497.1 - 1.8 8.7 5.8 0.35 11.0 1.6 1.8 2 0 0 2 2 2 0 Vitamin K epoxide reductase family DUF4470 PF14737.6 EGO54498.1 - 0.1 12.8 0.1 0.36 11.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) Ank_2 PF12796.7 EGO54499.1 - 2.9e-05 24.6 0.0 5.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO54499.1 - 0.0025 18.2 0.0 0.028 14.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EGO54499.1 - 0.016 15.7 0.0 0.058 13.9 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeat zf-RING_4 PF14570.6 EGO54499.1 - 0.016 15.0 1.3 0.016 15.0 1.3 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 EGO54499.1 - 0.022 15.1 3.7 0.022 15.1 3.7 1.7 2 0 0 2 2 2 0 Ring finger domain CH PF00307.31 EGO54500.1 - 3.4e-68 226.7 0.0 1.7e-18 66.8 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 EGO54500.1 - 1.1e-05 25.8 0.0 0.00021 21.7 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGO54500.1 - 0.0034 16.8 0.6 0.58 9.8 0.3 3.2 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 EGO54500.1 - 0.0037 17.1 0.5 0.18 11.9 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain MBOAT PF03062.19 EGO54501.1 - 1e-46 159.9 28.0 1.8e-46 159.1 20.3 2.4 2 1 0 3 3 3 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EGO54501.1 - 6e-06 26.4 5.5 1.8e-05 24.9 5.5 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RRM_1 PF00076.22 EGO54502.1 - 1.5e-11 43.9 0.0 2.1e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGO54502.1 - 0.00014 21.8 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.27 EGO54503.1 - 5.8e-74 244.1 1.5 1e-25 89.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGO54503.1 - 5.8e-05 22.4 0.1 0.0039 16.4 0.0 3.0 2 1 0 2 2 2 2 Gammaproteobacterial serine protease Ribosomal_L18 PF17135.4 EGO54504.1 - 1.2e-92 308.4 4.6 1.4e-92 308.3 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EGO54504.1 - 0.00049 20.8 0.2 0.00049 20.8 0.2 2.0 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TBPIP PF07106.13 EGO54504.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain DDHD PF02862.17 EGO54505.1 - 2.5e-64 217.5 0.1 2.5e-64 217.5 0.1 4.6 3 1 0 3 3 3 1 DDHD domain FtsJ PF01728.19 EGO54505.1 - 3.4e-45 154.3 12.7 1.5e-44 152.2 12.7 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase LIDHydrolase PF10230.9 EGO54505.1 - 0.0083 15.7 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase RNA_pol_Rpb1_5 PF04998.17 EGO54506.1 - 7.5e-78 261.6 0.1 1.2e-77 261.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 EGO54506.1 - 4.4e-66 223.3 0.0 7.7e-66 222.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EGO54506.1 - 2.8e-59 200.1 0.0 6.3e-59 198.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGO54506.1 - 6.3e-35 120.4 0.0 1.3e-34 119.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EGO54506.1 - 1e-29 102.6 0.1 2.9e-29 101.2 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 TRM13 PF05206.14 EGO54506.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase TRM13 TFIID_30kDa PF03540.13 EGO54506.1 - 0.096 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit SRAP PF02586.14 EGO54507.1 - 2e-77 259.6 0.0 2.6e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Macoilin PF09726.9 EGO54508.1 - 0.27 9.8 10.6 0.27 9.7 10.6 1.0 1 0 0 1 1 1 0 Macoilin family Peptidase_S64 PF08192.11 EGO54508.1 - 0.52 8.7 11.5 0.57 8.6 11.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Mucin PF01456.17 EGO54508.1 - 0.85 9.6 22.8 1.3 9.1 22.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SOG2 PF10428.9 EGO54508.1 - 1 8.5 16.2 1.1 8.4 16.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4551 PF15087.6 EGO54508.1 - 1.2 7.9 8.7 1.2 7.9 8.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Zip PF02535.22 EGO54508.1 - 1.5 8.0 3.1 1.5 7.9 3.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Menin PF05053.13 EGO54508.1 - 2.3 6.5 17.9 2.9 6.1 17.9 1.1 1 0 0 1 1 1 0 Menin HSP70 PF00012.20 EGO54511.1 - 3.9e-267 887.3 13.7 4.4e-267 887.1 13.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGO54511.1 - 7.2e-18 64.5 1.5 2.8e-16 59.2 0.5 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EGO54511.1 - 0.00086 19.7 4.3 1.2 9.5 0.3 3.7 3 1 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 EGO54511.1 - 0.0089 15.0 0.2 0.086 11.8 0.1 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain DUF1464 PF07318.12 EGO54511.1 - 0.027 13.6 1.1 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) HEPPP_synt_1 PF07307.11 EGO54511.1 - 0.035 13.7 0.8 0.072 12.7 0.8 1.4 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Hydantoinase_A PF01968.18 EGO54511.1 - 0.17 11.1 4.6 0.6 9.3 0.1 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase GTP_EFTU PF00009.27 EGO54512.1 - 7.8e-46 156.1 0.1 1.4e-45 155.2 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 EGO54512.1 - 2.2e-23 82.3 1.1 5.1e-23 81.2 1.1 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 EGO54512.1 - 5.3e-10 39.6 0.1 2.7e-09 37.3 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EGO54512.1 - 1.3e-07 31.7 0.0 1.3e-05 25.2 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EGO54512.1 - 9.6e-05 22.7 0.2 0.00038 20.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Roc PF08477.13 EGO54512.1 - 0.00037 20.7 0.0 0.025 14.8 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGO54512.1 - 0.017 14.5 0.0 3.1 7.2 0.0 2.5 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Arf PF00025.21 EGO54512.1 - 0.032 13.7 0.1 5.8 6.3 0.1 2.5 1 1 1 2 2 2 0 ADP-ribosylation factor family Ras PF00071.22 EGO54512.1 - 0.035 13.7 0.1 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 Ras family FeoB_N PF02421.18 EGO54512.1 - 0.1 12.1 0.1 1.6 8.2 0.0 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B Cpn60_TCP1 PF00118.24 EGO54513.1 - 8.8e-157 522.6 4.5 1e-156 522.5 4.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 EGO54513.1 - 0.18 12.0 3.2 8.4 6.6 0.1 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain BATS PF06968.13 EGO54514.1 - 1.7e-21 76.2 0.0 3.8e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EGO54514.1 - 6.9e-14 52.6 0.1 1.1e-13 51.9 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily COesterase PF00135.28 EGO54515.1 - 8.6e-65 219.5 0.0 1.2e-64 219.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO54515.1 - 3.9e-06 26.9 0.3 4.2e-05 23.5 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold zf-C2H2 PF00096.26 EGO54518.1 - 5.2e-21 73.9 25.2 1.4e-05 25.3 1.6 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO54518.1 - 3.9e-18 65.0 28.5 2.5e-06 27.7 1.4 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO54518.1 - 5.7e-11 42.3 22.8 0.0021 18.7 1.4 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGO54518.1 - 2.4e-05 24.5 1.6 3.2 8.1 0.0 4.9 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EGO54518.1 - 0.0005 19.8 0.4 0.0005 19.8 0.4 3.1 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 EGO54518.1 - 0.014 15.5 0.4 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger zf_UBZ PF18439.1 EGO54518.1 - 0.023 14.3 1.1 0.55 9.9 0.3 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 EGO54518.1 - 0.083 13.3 11.7 11 6.6 0.6 4.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type C1_4 PF07975.12 EGO54518.1 - 0.15 12.3 1.7 4.1 7.7 0.0 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain zf-MYST PF17772.1 EGO54518.1 - 0.53 9.9 2.7 20 4.9 0.0 2.8 3 0 0 3 3 3 0 MYST family zinc finger domain XPA_N PF01286.18 EGO54518.1 - 0.73 9.9 4.7 1 9.4 0.7 2.9 3 0 0 3 3 3 0 XPA protein N-terminal zf-TRAF PF02176.18 EGO54518.1 - 1.7 9.4 9.6 4.6 8.0 0.8 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger IBR PF01485.21 EGO54518.1 - 1.8 8.8 7.0 16 5.8 1.1 3.0 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-CRD PF17979.1 EGO54518.1 - 2.6 8.2 8.5 6 7.0 2.2 2.3 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions FOXP-CC PF16159.5 EGO54518.1 - 3.4 8.4 7.2 11 6.8 0.2 3.4 3 1 1 4 4 4 0 FOXP coiled-coil domain Zn-ribbon_8 PF09723.10 EGO54518.1 - 7.5 6.8 9.0 10 6.3 1.3 3.1 1 1 3 4 4 4 0 Zinc ribbon domain zf-LYAR PF08790.11 EGO54518.1 - 8.3 6.4 6.1 2.4 8.1 0.2 2.9 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger TMF_DNA_bd PF12329.8 EGO54519.1 - 0.0021 18.0 6.5 0.0021 18.0 6.5 9.6 5 3 3 9 9 9 3 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 EGO54519.1 - 0.0027 17.7 15.5 0.0027 17.7 15.5 6.3 2 2 5 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 EGO54519.1 - 0.55 9.1 100.0 0.022 13.7 9.2 6.3 1 1 5 6 6 6 0 Spc7 kinetochore protein FAA_hydro_N_2 PF18288.1 EGO54519.1 - 4.4 7.8 9.0 17 5.9 0.2 4.2 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 KIP1 PF07765.12 EGO54519.1 - 4.5 7.5 9.3 0.39 10.9 2.0 3.2 3 0 0 3 3 3 0 KIP1-like protein DUF4806 PF16064.5 EGO54519.1 - 6.5 7.1 11.0 1.9 8.8 0.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4806) Ribosomal_L33 PF00471.20 EGO54520.1 - 4.8e-06 26.9 0.0 5.8e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Aminotran_1_2 PF00155.21 EGO54522.1 - 1e-38 133.5 0.0 1.3e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGO54522.1 - 0.13 10.8 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RPN7 PF10602.9 EGO54523.1 - 2.3e-57 193.5 1.3 3e-57 193.1 0.3 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 EGO54523.1 - 1.7e-14 54.2 0.0 4.1e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain Pox_MCEL PF03291.16 EGO54524.1 - 7.2e-71 239.0 0.0 5e-47 160.6 0.0 2.3 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 EGO54524.1 - 1.1e-09 38.9 0.0 0.00021 21.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EGO54524.1 - 1.8e-08 35.0 0.0 0.003 18.3 0.0 2.9 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGO54524.1 - 1.5e-05 25.5 0.0 0.34 11.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EGO54524.1 - 3.1e-05 23.8 0.0 0.018 14.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Raftlin PF15250.6 EGO54524.1 - 8e-05 21.6 0.3 8e-05 21.6 0.3 2.1 2 0 0 2 2 2 1 Raftlin Methyltransf_23 PF13489.6 EGO54524.1 - 0.00013 21.8 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EGO54524.1 - 0.00044 19.5 0.0 0.00081 18.6 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family FAM92 PF06730.11 EGO54524.1 - 0.25 10.7 4.4 0.44 9.9 4.4 1.3 1 0 0 1 1 1 0 FAM92 protein SAPS PF04499.15 EGO54524.1 - 0.38 9.5 3.3 1 8.1 0.0 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Flavokinase PF01687.17 EGO54525.1 - 7.9e-34 116.3 0.0 9.7e-34 116.0 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase PepSY_TM PF03929.16 EGO54525.1 - 0.16 11.6 0.1 0.2 11.3 0.1 1.1 1 0 0 1 1 1 0 PepSY-associated TM region DUF2722 PF10846.8 EGO54525.1 - 0.37 9.7 8.5 0.46 9.4 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Clr5 PF14420.6 EGO54527.1 - 7.6e-11 42.1 5.2 1.5e-10 41.1 5.2 1.5 1 1 0 1 1 1 1 Clr5 domain zf-Nse PF11789.8 EGO54528.1 - 1.9e-19 69.2 0.3 3.3e-19 68.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 EGO54528.1 - 0.0017 18.4 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EGO54528.1 - 0.0048 16.7 0.6 0.0078 16.0 0.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 EGO54528.1 - 0.01 15.5 0.2 0.019 14.7 0.2 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.7 EGO54528.1 - 0.042 14.1 0.1 0.083 13.2 0.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGO54528.1 - 0.042 14.2 0.3 0.069 13.5 0.3 1.4 1 0 0 1 1 1 0 Ring finger domain DUF1640 PF07798.11 EGO54528.1 - 0.063 13.3 0.5 0.12 12.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) ADIP PF11559.8 EGO54528.1 - 0.082 13.0 3.3 0.18 11.9 2.4 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding zf-RING_UBOX PF13445.6 EGO54528.1 - 0.24 11.5 0.7 0.53 10.4 0.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Rtf2 PF04641.12 EGO54528.1 - 0.96 8.8 8.6 0.23 10.8 1.1 2.7 2 1 0 2 2 2 0 Rtf2 RING-finger PAS_9 PF13426.7 EGO54529.1 - 2e-16 60.1 0.0 2.7e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EGO54529.1 - 0.0017 18.3 0.0 0.006 16.6 0.0 1.8 1 1 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EGO54529.1 - 0.003 17.8 0.0 0.023 15.0 0.0 2.2 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EGO54529.1 - 0.0036 17.5 0.0 0.0075 16.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EGO54529.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 PAS domain EF_assoc_2 PF08356.12 EGO54530.1 - 3.4e-36 123.1 0.0 7.1e-36 122.1 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 EGO54530.1 - 4.1e-32 109.6 1.0 9.2e-32 108.5 1.0 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 EGO54530.1 - 2.1e-25 89.2 0.0 3.5e-16 59.2 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGO54530.1 - 1.4e-14 54.3 0.0 3.3e-09 37.0 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGO54530.1 - 2.8e-08 33.8 0.0 8.1e-05 22.7 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO54530.1 - 2.7e-06 27.4 0.7 0.2 11.6 0.0 3.4 2 1 0 3 3 3 2 RsgA GTPase EF-hand_1 PF00036.32 EGO54530.1 - 3.4e-06 26.2 4.8 0.028 14.0 0.5 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGO54530.1 - 1.3e-05 25.6 1.3 0.016 15.6 0.4 2.6 2 0 0 2 2 2 2 EF-hand domain pair AAA_29 PF13555.6 EGO54530.1 - 3.9e-05 23.3 0.1 0.054 13.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran PF00005.27 EGO54530.1 - 5e-05 23.8 0.0 0.079 13.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EGO54530.1 - 0.0001 22.8 0.1 0.19 12.1 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGO54530.1 - 0.00017 21.9 0.0 0.21 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain EF-hand_6 PF13405.6 EGO54530.1 - 0.00018 21.1 3.9 0.14 12.2 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain GTP_EFTU PF00009.27 EGO54530.1 - 0.0013 18.4 0.0 4.4 6.8 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EGO54530.1 - 0.0022 18.1 0.9 1.1 9.3 0.4 3.1 2 1 1 3 3 3 1 Dynamin family AAA_24 PF13479.6 EGO54530.1 - 0.0033 17.2 0.0 0.33 10.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGO54530.1 - 0.0074 16.7 0.0 1.7 9.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Ploopntkinase3 PF18751.1 EGO54530.1 - 0.013 15.4 0.0 5.7 6.8 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 EGO54530.1 - 0.032 14.2 0.0 3.8 7.4 0.0 2.9 3 0 0 3 3 2 0 NACHT domain DUF87 PF01935.17 EGO54530.1 - 0.032 14.3 0.1 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_28 PF13521.6 EGO54530.1 - 0.044 14.0 0.0 6.1 7.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EGO54530.1 - 0.045 12.9 0.1 2.9 7.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 EGO54530.1 - 0.049 13.8 0.0 15 5.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain IIGP PF05049.13 EGO54530.1 - 0.077 12.0 0.3 1.6 7.7 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Septin PF00735.18 EGO54530.1 - 0.085 12.1 0.0 0.99 8.6 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_23 PF13476.6 EGO54530.1 - 0.098 13.2 0.3 9.6 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGO54530.1 - 0.11 12.0 0.0 1.7 8.1 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 EGO54530.1 - 0.19 12.3 0.1 2.9 8.5 0.2 2.6 2 0 0 2 2 2 0 AAA domain EF-hand_5 PF13202.6 EGO54530.1 - 2.6 7.7 6.5 1.8 8.2 1.5 2.6 2 0 0 2 2 2 0 EF hand WD40 PF00400.32 EGO54531.1 - 5.7e-13 49.1 16.0 0.00039 21.2 0.4 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO54531.1 - 5.1e-09 36.3 0.1 0.00038 20.7 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGO54531.1 - 1.4e-05 25.0 0.1 0.011 15.6 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EGO54531.1 - 0.012 13.6 0.0 0.023 12.7 0.0 1.4 1 1 0 1 1 1 0 IKI3 family Cytochrom_D1 PF02239.16 EGO54531.1 - 0.097 11.2 0.0 0.19 10.2 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain Atx10homo_assoc PF09759.9 EGO54532.1 - 5.3e-10 39.2 0.0 1.3e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain SR-25 PF10500.9 EGO54532.1 - 1.1 8.8 6.2 1.8 8.1 6.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Menin PF05053.13 EGO54532.1 - 2.4 6.4 10.5 4 5.7 10.5 1.3 1 0 0 1 1 1 0 Menin Zip PF02535.22 EGO54532.1 - 3 7.0 6.2 5.1 6.2 6.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PNP_UDP_1 PF01048.20 EGO54533.1 - 1.9e-40 138.6 0.5 2.3e-40 138.3 0.5 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Med13_C PF06333.12 EGO54534.1 - 1.3e-83 281.0 24.5 1.4e-83 281.0 12.6 3.8 3 1 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 EGO54534.1 - 1.3e-26 93.8 0.0 1.3e-26 93.8 0.0 2.8 3 0 0 3 3 3 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 EGO54534.1 - 4.5e-14 52.8 22.5 1.6e-06 28.1 0.0 3.9 3 1 1 4 4 4 3 MID domain of medPIWI DUF3405 PF11885.8 EGO54534.1 - 0.057 12.0 2.5 0.11 11.1 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) CPSF100_C PF13299.6 EGO54534.1 - 1.7 8.8 4.7 4.6 7.4 4.7 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 EGO54534.1 - 6.6 5.4 8.0 15 4.2 8.0 1.5 1 0 0 1 1 1 0 Presenilin NUC153 PF08159.12 EGO54535.1 - 1.3e-11 44.1 0.8 2.9e-11 43.0 0.8 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EGO54535.1 - 0.0026 18.5 0.0 12 6.9 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO54535.1 - 0.031 14.6 0.0 0.086 13.2 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain COQ7 PF03232.13 EGO54538.1 - 9.8e-72 240.3 0.2 1.2e-71 240.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Vitellogenin_N PF01347.22 EGO54538.1 - 0.011 14.2 0.0 0.013 13.9 0.0 1.0 1 0 0 1 1 1 0 Lipoprotein amino terminal region Plus-3 PF03126.18 EGO54539.1 - 3e-29 101.7 0.1 8.7e-29 100.2 0.0 1.8 2 0 0 2 2 2 1 Plus-3 domain PLDc PF00614.22 EGO54540.1 - 1.2e-17 63.2 0.4 8.1e-09 35.3 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EGO54540.1 - 6.1e-13 48.8 0.0 2.6e-07 30.6 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 EGO54540.1 - 6.8e-08 32.5 0.0 3.2e-06 27.1 0.0 2.9 2 1 0 2 2 2 1 PX domain Tubulin PF00091.25 EGO54541.1 - 1e-68 231.5 0.0 1.5e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGO54541.1 - 3.3e-46 156.6 0.3 9.4e-46 155.1 0.1 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGO54541.1 - 3.9e-06 27.2 0.0 1.2e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Oxidored_q6 PF01058.22 EGO54542.1 - 3.1e-22 78.8 0.0 4.6e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Mpp10 PF04006.12 EGO54543.1 - 4.4e-110 369.0 68.6 1.5e-109 367.2 68.6 1.7 1 1 0 1 1 1 1 Mpp10 protein SSP160 PF06933.11 EGO54543.1 - 0.03 12.6 4.9 0.048 11.9 4.9 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SPX PF03105.19 EGO54544.1 - 1.1e-13 51.9 16.0 7e-07 29.5 0.0 4.1 2 1 2 4 4 4 3 SPX domain HAUS4 PF14735.6 EGO54544.1 - 0.031 14.0 1.8 0.067 12.9 0.9 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 4 SIKE PF05769.11 EGO54544.1 - 0.086 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 SIKE family COMMD1_N PF17221.3 EGO54544.1 - 0.088 13.1 0.0 0.87 9.9 0.0 2.2 2 0 0 2 2 2 0 COMMD1 N-terminal domain mCpol PF18182.1 EGO54544.1 - 0.12 12.8 0.0 0.28 11.5 0.0 1.7 1 1 0 1 1 1 0 minimal CRISPR polymerase domain NMO PF03060.15 EGO54545.1 - 3.1e-39 135.3 6.2 2.4e-33 116.0 2.7 2.0 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EGO54545.1 - 5.9e-09 35.4 6.4 9.4e-09 34.8 6.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EGO54545.1 - 1.7e-06 27.3 6.9 0.0065 15.5 5.8 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EGO54545.1 - 0.00052 19.3 2.2 0.00076 18.7 2.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Amidohydro_3 PF07969.11 EGO54546.1 - 3.2e-53 181.9 0.6 2.2e-51 175.8 0.0 2.0 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EGO54546.1 - 0.0056 16.0 0.2 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase family HECT PF00632.25 EGO54547.1 - 1e-96 324.1 0.0 1.5e-96 323.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EGO54547.1 - 6.1e-33 112.6 19.3 1.1e-12 47.8 1.9 4.1 4 0 0 4 4 4 3 WW domain C2 PF00168.30 EGO54547.1 - 4.4e-19 68.7 0.1 1.2e-18 67.3 0.1 1.8 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.22 EGO54548.1 - 1.1e-16 60.3 0.0 2e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO54548.1 - 0.019 14.8 0.1 0.31 10.9 0.0 2.6 2 2 0 2 2 2 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGO54548.1 - 0.049 13.7 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF2550 PF10739.9 EGO54548.1 - 0.07 13.1 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) Spc7 PF08317.11 EGO54548.1 - 1 8.2 14.3 1.6 7.5 14.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PA26 PF04636.13 EGO54548.1 - 1.7 7.5 6.1 1.9 7.3 6.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF935 PF06074.12 EGO54548.1 - 2 7.1 9.2 2.5 6.8 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) RRN3 PF05327.11 EGO54548.1 - 2 6.8 7.8 2.4 6.6 7.8 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Presenilin PF01080.17 EGO54548.1 - 2.6 6.7 8.7 2.7 6.7 8.7 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 EGO54548.1 - 3.8 7.1 11.8 5.3 6.6 11.8 1.3 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 EGO54548.1 - 4.3 5.9 4.4 4.5 5.8 4.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ZapB PF06005.12 EGO54548.1 - 6.6 7.3 20.9 0.15 12.5 2.9 2.2 2 0 0 2 2 2 0 Cell division protein ZapB PNISR PF15996.5 EGO54548.1 - 8.2 6.7 18.1 11 6.3 18.1 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DivIC PF04977.15 EGO54548.1 - 8.4 6.2 17.4 2.9 7.7 3.1 2.2 2 0 0 2 2 2 0 Septum formation initiator Hydin_ADK PF17213.3 EGO54548.1 - 9.8 6.4 8.0 14 5.9 8.0 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain WD40 PF00400.32 EGO54550.1 - 5.3e-37 125.2 33.3 0.00011 22.9 0.6 11.8 13 0 0 13 13 13 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO54550.1 - 4e-17 62.3 4.3 0.0028 17.9 0.2 8.3 5 3 4 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGO54550.1 - 0.0032 17.4 2.2 19 5.4 0.0 6.0 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Lactonase PF10282.9 EGO54550.1 - 0.0063 15.8 0.7 1.4 8.1 0.1 2.8 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller Ge1_WD40 PF16529.5 EGO54550.1 - 0.0066 15.4 7.5 2.6 6.9 0.0 5.7 7 1 0 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EGO54550.1 - 0.0077 14.8 0.0 3.8 6.0 0.0 2.8 2 2 0 2 2 2 2 Cytochrome D1 heme domain MFS_1 PF07690.16 EGO54551.1 - 1.3e-41 142.8 44.6 2.7e-41 141.7 35.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGO54551.1 - 7.5e-05 21.3 5.3 7.5e-05 21.3 5.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pex14_N PF04695.13 EGO54551.1 - 0.026 15.2 3.4 0.1 13.2 3.4 1.9 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAS PF00989.25 EGO54553.1 - 3.6e-05 23.7 0.0 7.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 EGO54553.1 - 0.0025 17.9 8.9 0.0056 16.8 8.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_4 PF08448.10 EGO54553.1 - 0.043 14.1 0.0 0.34 11.2 0.0 2.3 2 0 0 2 2 2 0 PAS fold PXA PF02194.15 EGO54554.1 - 1.5e-53 181.5 0.3 6.5e-53 179.4 0.1 2.3 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 EGO54554.1 - 5.5e-28 97.8 0.0 1.6e-27 96.3 0.0 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 EGO54554.1 - 3e-20 72.3 0.6 8.3e-20 70.9 0.6 1.8 1 0 0 1 1 1 1 PX domain RGS PF00615.19 EGO54554.1 - 6e-10 39.4 0.0 1.8e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain Methyltransf_4 PF02390.17 EGO54555.1 - 9e-54 181.5 0.1 1.5e-53 180.8 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EGO54555.1 - 5.8e-05 23.7 0.0 0.00024 21.8 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 EGO54555.1 - 0.0023 17.5 0.0 0.0062 16.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGO54555.1 - 0.0028 17.5 0.0 0.0043 16.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO54555.1 - 0.018 15.7 0.0 0.06 14.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DbpA PF03880.15 EGO54555.1 - 0.029 14.3 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 DbpA RNA binding domain Methyltransf_32 PF13679.6 EGO54555.1 - 0.059 13.4 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGO54555.1 - 0.081 13.6 0.0 0.51 11.0 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Homoserine_dh PF00742.19 EGO54556.1 - 1.3e-51 174.9 0.0 2.1e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EGO54556.1 - 9.5e-17 61.7 0.0 1.7e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Glyco_trans_4_5 PF16994.5 EGO54556.1 - 0.028 14.0 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl-transferase family 4 PglD_N PF17836.1 EGO54556.1 - 0.12 13.0 0.6 0.39 11.4 0.0 2.2 2 0 0 2 2 2 0 PglD N-terminal domain DUF4078 PF13300.6 EGO54558.1 - 5.9e-31 106.6 15.8 5.9e-31 106.6 15.8 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4078) TC1 PF15063.6 EGO54558.1 - 0.084 12.8 1.3 0.25 11.2 1.3 1.8 1 0 0 1 1 1 0 Thyroid cancer protein 1 Zn_clus PF00172.18 EGO54559.1 - 2.5e-08 33.9 7.7 4.2e-08 33.2 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGO54559.1 - 0.0016 17.3 1.3 0.0022 16.9 1.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 EGO54560.1 - 2.9e-87 293.0 0.1 3.7e-87 292.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CAMSAP_CH PF11971.8 EGO54560.1 - 0.21 11.4 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain KCH PF16944.5 EGO54561.1 - 1.9e-94 316.1 11.9 2.5e-94 315.7 11.9 1.1 1 0 0 1 1 1 1 Fungal potassium channel MRP-S28 PF10213.9 EGO54563.1 - 5.1e-37 127.1 0.0 9.4e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Glyco_tran_28_C PF04101.16 EGO54564.1 - 1e-18 67.9 0.0 3.1e-18 66.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Abhydrolase_6 PF12697.7 EGO54565.1 - 7.5e-12 46.3 0.3 1.1e-11 45.8 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO54565.1 - 1.5e-07 31.0 0.0 3.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO54565.1 - 0.0012 18.5 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EGO54565.1 - 0.0047 15.9 0.0 0.08 11.8 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 EGO54565.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ndr PF03096.14 EGO54565.1 - 0.25 10.0 0.0 0.4 9.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family PTCB-BRCT PF12738.7 EGO54566.1 - 3e-34 116.8 3.0 8.4e-22 76.9 0.2 4.5 4 1 0 4 4 4 3 twin BRCT domain RTT107_BRCT_5 PF16770.5 EGO54566.1 - 1.8e-31 107.9 0.0 8.8e-29 99.3 0.0 3.8 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 EGO54566.1 - 1.1e-24 86.7 0.0 0.00018 21.8 0.0 5.8 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGO54566.1 - 4e-23 81.6 0.1 1.1e-07 32.1 0.0 4.9 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EGO54566.1 - 3.1e-10 40.2 0.3 0.0095 16.2 0.0 3.9 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EGO54566.1 - 0.0019 18.2 0.0 4.4 7.4 0.0 3.3 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain HMG_CoA_synt_C PF08540.10 EGO54567.1 - 2.6e-102 342.2 0.1 3.3e-102 341.9 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EGO54567.1 - 2.6e-96 320.5 0.2 3.9e-96 319.9 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal BCS1_N PF08740.11 EGO54568.1 - 1.5e-56 191.4 1.1 1.5e-56 191.4 1.1 2.8 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 EGO54568.1 - 1.4e-16 61.2 0.0 3.3e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGO54568.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGO54568.1 - 0.0052 16.8 0.0 0.041 13.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) PI3K_1B_p101 PF10486.9 EGO54568.1 - 0.0083 14.0 19.8 0.012 13.4 19.8 1.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit AAA_25 PF13481.6 EGO54568.1 - 0.0094 15.5 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO54568.1 - 0.011 16.1 1.6 0.02 15.3 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EGO54568.1 - 0.036 14.6 0.3 0.2 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.9 EGO54568.1 - 0.043 12.4 22.7 0.061 11.9 22.7 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EGO54568.1 - 0.54 9.0 22.6 0.82 8.5 22.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain LAP1C PF05609.12 EGO54568.1 - 0.83 8.7 20.9 1.3 8.0 20.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) AAA_11 PF13086.6 EGO54568.1 - 0.94 9.2 0.0 0.94 9.2 0.0 3.1 2 1 0 2 2 1 0 AAA domain Asp-B-Hydro_N PF05279.11 EGO54568.1 - 2.4 8.2 22.7 3.9 7.5 22.7 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GREB1 PF15782.5 EGO54568.1 - 3 4.9 15.6 4.2 4.4 15.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAP1 PF08601.10 EGO54568.1 - 3.6 7.2 22.3 6.3 6.4 22.3 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 SR-25 PF10500.9 EGO54568.1 - 5.8 6.5 49.8 14 5.2 49.8 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_S64 PF08192.11 EGO54568.1 - 6.6 5.1 23.3 9.1 4.6 23.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 SelP_N PF04592.14 EGO54571.1 - 2 7.8 8.1 3 7.2 8.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Cellulase PF00150.18 EGO54574.1 - 9.3e-12 45.0 0.2 9.3e-12 45.0 0.2 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) SNARE PF05739.19 EGO54574.1 - 0.28 11.2 3.1 0.53 10.3 3.1 1.4 1 0 0 1 1 1 0 SNARE domain OAD_gamma PF04277.13 EGO54574.1 - 0.45 11.1 2.2 11 6.7 0.0 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Synaptobrevin PF00957.21 EGO54574.1 - 7.6 6.4 6.7 13 5.7 6.7 1.3 1 0 0 1 1 1 0 Synaptobrevin Transket_pyr PF02779.24 EGO54575.1 - 5.3e-42 143.5 0.0 8.9e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGO54575.1 - 4.5e-33 113.8 0.1 8.7e-33 112.9 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EGO54575.1 - 0.0096 16.2 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II F-actin_cap_A PF01267.17 EGO54576.1 - 4.2e-95 318.2 0.1 4.7e-95 318.0 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Cyt-b5 PF00173.28 EGO54577.1 - 2.5e-24 85.2 0.1 3.2e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TPR_21 PF09976.9 EGO54577.1 - 0.16 11.7 1.3 0.2 11.3 0.3 1.7 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain YqzH PF14164.6 EGO54577.1 - 0.17 12.0 1.9 0.3 11.2 1.9 1.3 1 0 0 1 1 1 0 YqzH-like protein TFA2_Winged_2 PF18121.1 EGO54578.1 - 1.5e-23 82.3 0.2 8.2e-23 79.9 0.2 2.0 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EGO54578.1 - 8.1e-07 29.2 0.0 2.1e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain DUF3886 PF13025.6 EGO54578.1 - 0.082 13.1 0.6 0.17 12.1 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Tricorn_C1 PF14684.6 EGO54578.1 - 0.092 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease C1 domain HIM1 PF08732.10 EGO54579.1 - 1.6e-09 37.5 0.0 2.9e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 HIM1 Epimerase PF01370.21 EGO54579.1 - 1.4e-08 34.5 0.0 3.2e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGO54579.1 - 4.8e-08 33.1 0.2 7.5e-08 32.5 0.0 1.4 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EGO54579.1 - 7.8e-05 22.3 0.2 0.00047 19.8 0.2 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EGO54579.1 - 0.0011 18.2 0.0 0.41 9.8 0.0 2.6 2 1 1 3 3 3 2 Male sterility protein Semialdhyde_dh PF01118.24 EGO54579.1 - 0.029 14.8 0.0 0.066 13.6 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EGO54579.1 - 0.078 12.0 0.0 9 5.2 0.0 2.4 2 1 1 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family WGG PF10273.9 EGO54580.1 - 9.5e-37 125.5 0.8 1.4e-36 125.0 0.8 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 BSD PF03909.17 EGO54581.1 - 4.8e-20 71.3 0.1 9.5e-20 70.4 0.1 1.5 1 0 0 1 1 1 1 BSD domain Suf PF05843.14 EGO54581.1 - 0.00044 20.3 1.2 0.00044 20.3 1.2 2.2 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) ATG16 PF08614.11 EGO54581.1 - 0.0099 16.1 10.7 0.0099 16.1 10.7 2.9 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) Phage_Mu_F PF04233.14 EGO54581.1 - 0.028 15.2 0.1 0.11 13.3 0.1 1.9 1 0 0 1 1 1 0 Phage Mu protein F like protein TPR_2 PF07719.17 EGO54581.1 - 0.15 12.2 0.8 0.59 10.4 0.8 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat PAP1 PF08601.10 EGO54582.1 - 1.5e-91 308.0 36.0 8.8e-60 203.4 3.3 3.6 2 1 1 3 3 3 2 Transcription factor PAP1 bZIP_1 PF00170.21 EGO54582.1 - 7.8e-08 32.3 16.1 1.7e-07 31.3 16.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 EGO54582.1 - 3.8e-05 23.5 3.5 3.8e-05 23.5 3.5 1.6 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 NAM-associated PF14303.6 EGO54582.1 - 0.0066 17.2 14.3 0.024 15.4 14.3 1.9 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain Ssl1 PF04056.14 EGO54582.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Ssl1-like dsrm PF00035.26 EGO54582.1 - 0.036 14.8 0.1 0.088 13.5 0.1 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif JIP_LZII PF16471.5 EGO54582.1 - 0.12 12.6 8.1 7.5 6.8 5.2 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Cluap1 PF10234.9 EGO54582.1 - 0.19 11.1 6.8 0.34 10.3 6.8 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 GAS PF13851.6 EGO54582.1 - 0.36 10.2 12.4 0.051 12.9 8.3 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_2 PF07716.15 EGO54582.1 - 0.73 10.0 15.7 1.7 8.8 15.2 1.8 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.17 EGO54582.1 - 1.2 9.7 11.9 0.69 10.5 9.0 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor UPF0242 PF06785.11 EGO54582.1 - 3.3 7.8 7.8 5.8 7.0 7.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Abhydrolase_3 PF07859.13 EGO54584.1 - 2.5e-56 190.9 0.0 3.7e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO54584.1 - 0.00041 19.3 0.1 0.0084 15.0 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase Pex14_N PF04695.13 EGO54586.1 - 2.7e-32 112.6 0.9 2.7e-32 112.6 0.9 2.7 2 2 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CR6_interact PF10147.9 EGO54586.1 - 0.00015 21.5 0.5 0.00025 20.8 0.5 1.3 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 zf-C4H2 PF10146.9 EGO54586.1 - 0.00027 21.3 3.7 0.00048 20.5 3.7 1.4 1 0 0 1 1 1 1 Zinc finger-containing protein DUF1978 PF09321.10 EGO54586.1 - 0.00081 18.8 6.5 0.0012 18.2 6.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1978) BicD PF09730.9 EGO54586.1 - 0.0019 16.7 7.0 0.0027 16.2 7.0 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D LMBR1 PF04791.16 EGO54586.1 - 0.005 15.8 0.6 0.0058 15.6 0.6 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF16 PF01519.16 EGO54586.1 - 0.01 16.3 4.6 0.72 10.4 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 Golgin_A5 PF09787.9 EGO54586.1 - 0.011 15.3 10.6 0.011 15.3 10.6 1.4 2 0 0 2 2 1 0 Golgin subfamily A member 5 DUF3584 PF12128.8 EGO54586.1 - 0.025 12.1 11.4 0.037 11.6 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prominin PF05478.11 EGO54586.1 - 0.026 12.5 1.6 0.035 12.1 1.6 1.1 1 0 0 1 1 1 0 Prominin 5_nucleotid PF05761.14 EGO54586.1 - 0.057 12.3 3.6 0.087 11.7 3.6 1.2 1 0 0 1 1 1 0 5' nucleotidase family Phg_2220_C PF09524.10 EGO54586.1 - 0.1 12.7 0.1 0.32 11.1 0.0 1.8 2 0 0 2 2 1 0 Conserved phage C-terminus (Phg_2220_C) DUF2939 PF11159.8 EGO54586.1 - 0.13 12.7 5.0 0.081 13.4 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) UPF0242 PF06785.11 EGO54586.1 - 0.13 12.3 6.2 0.24 11.5 6.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlgN PF05130.12 EGO54586.1 - 0.14 12.7 7.1 0.25 11.9 7.1 1.4 1 0 0 1 1 1 0 FlgN protein Exonuc_VII_L PF02601.15 EGO54586.1 - 0.14 11.7 3.5 0.23 11.0 3.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit HLH PF00010.26 EGO54586.1 - 0.18 11.8 4.0 21 5.2 1.5 3.0 2 1 0 2 2 2 0 Helix-loop-helix DNA-binding domain DUF1759 PF03564.15 EGO54586.1 - 0.23 11.4 1.6 0.37 10.7 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) DUF4211 PF13926.6 EGO54586.1 - 0.29 11.2 1.3 0.72 9.9 0.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4211) FUSC PF04632.12 EGO54586.1 - 0.44 9.0 2.6 0.65 8.5 2.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Occludin_ELL PF07303.13 EGO54586.1 - 0.77 10.5 3.6 3.2 8.5 3.6 2.0 1 1 0 1 1 1 0 Occludin homology domain Baculo_PEP_C PF04513.12 EGO54586.1 - 0.87 9.6 9.9 1.1 9.3 1.5 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RasGAP_C PF03836.15 EGO54586.1 - 1.2 9.3 8.8 0.27 11.4 0.9 2.2 1 1 1 2 2 2 0 RasGAP C-terminus V_ATPase_I PF01496.19 EGO54586.1 - 1.6 6.5 5.1 2.2 6.1 5.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 EGO54586.1 - 2.3 7.0 11.4 4 6.2 11.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Spectrin PF00435.21 EGO54586.1 - 2.6 8.6 9.6 7.4 7.1 8.1 2.3 1 1 0 1 1 1 0 Spectrin repeat TMPIT PF07851.13 EGO54586.1 - 3 7.0 6.7 8.9 5.4 6.7 1.8 1 1 0 1 1 1 0 TMPIT-like protein YabA PF06156.13 EGO54586.1 - 4.5 8.0 6.0 69 4.2 2.7 2.4 1 1 2 3 3 3 0 Initiation control protein YabA FIVAR PF07554.13 EGO54586.1 - 4.5 8.1 14.5 0.34 11.7 0.9 3.7 4 0 0 4 4 3 0 FIVAR domain KIP1 PF07765.12 EGO54586.1 - 4.7 7.4 6.0 41 4.4 0.1 2.8 2 1 1 3 3 3 0 KIP1-like protein DUF1043 PF06295.12 EGO54586.1 - 4.7 7.2 11.8 0.081 12.9 4.1 2.0 2 1 0 2 2 1 0 Protein of unknown function (DUF1043) ERM PF00769.19 EGO54586.1 - 7.2 6.3 17.7 20 4.9 17.7 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Ndc80_HEC PF03801.13 EGO54587.1 - 7e-61 204.3 0.0 1.5e-60 203.3 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family Spc7 PF08317.11 EGO54587.1 - 0.00029 19.8 38.9 0.027 13.4 14.4 2.7 2 0 0 2 2 2 2 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EGO54587.1 - 0.014 15.4 16.7 0.014 15.4 16.7 3.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein FliJ PF02050.16 EGO54587.1 - 0.14 12.4 35.3 0.35 11.1 14.0 3.7 2 2 2 4 4 4 0 Flagellar FliJ protein Filament PF00038.21 EGO54587.1 - 1.1 8.8 51.3 1.7 8.2 20.4 3.2 2 1 1 3 3 3 0 Intermediate filament protein DUF3584 PF12128.8 EGO54587.1 - 2.4 5.6 38.3 0.78 7.2 12.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF16 PF01519.16 EGO54587.1 - 2.7 8.5 26.5 0.38 11.3 8.9 3.5 2 2 1 3 3 3 0 Protein of unknown function DUF16 APG6_N PF17675.1 EGO54587.1 - 3 8.4 53.4 1 9.9 6.7 4.7 3 1 1 4 4 4 0 Apg6 coiled-coil region Mito_fiss_reg PF05308.11 EGO54587.1 - 3.6 7.6 13.0 0.063 13.4 4.4 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator DHR10 PF18595.1 EGO54587.1 - 5.1 7.2 46.5 0.077 13.1 20.5 3.7 2 2 0 2 2 2 0 Designed helical repeat protein 10 domain DUF4407 PF14362.6 EGO54587.1 - 7.1 5.9 26.0 2.4 7.4 8.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ESCRT-II PF05871.12 EGO54588.1 - 1.1e-51 174.8 0.0 1.3e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Transp_inhibit PF18791.1 EGO54588.1 - 0.063 12.8 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain KH_1 PF00013.29 EGO54589.1 - 2.3e-96 315.6 35.4 4.1e-13 49.0 0.3 12.2 12 1 0 12 12 12 10 KH domain SLS PF14611.6 EGO54589.1 - 4.8e-10 39.6 10.5 0.15 11.8 0.0 7.3 3 1 2 7 7 7 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 EGO54589.1 - 4.9e-10 39.1 28.1 0.0066 16.3 0.1 7.8 7 1 1 8 8 8 4 KH domain KH_4 PF13083.6 EGO54589.1 - 7.7e-05 22.5 12.6 0.041 13.8 0.2 5.5 6 0 0 6 6 6 2 KH domain FCD PF07729.12 EGO54589.1 - 0.9 10.0 10.8 1 9.8 0.0 4.1 4 0 0 4 4 4 0 FCD domain Acylphosphatase PF00708.18 EGO54589.1 - 3.1 8.3 7.5 2.1 8.8 0.1 4.4 5 0 0 5 5 5 0 Acylphosphatase Pkinase PF00069.25 EGO54593.1 - 5.2e-72 242.4 0.0 7.5e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO54593.1 - 7.8e-46 156.4 0.0 1.3e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EGO54593.1 - 2.7e-18 66.1 0.0 7.7e-18 64.6 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 EGO54593.1 - 1.1e-07 31.5 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGO54593.1 - 2.1e-06 26.8 0.0 2.1e-06 26.8 0.0 2.6 4 0 0 4 4 4 1 Fungal protein kinase Kdo PF06293.14 EGO54593.1 - 0.009 15.4 0.1 0.11 11.8 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO54593.1 - 0.068 13.1 3.9 0.19 11.6 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family DSHCT PF08148.12 EGO54593.1 - 0.13 12.0 0.0 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 DSHCT (NUC185) domain Haspin_kinase PF12330.8 EGO54593.1 - 0.15 11.0 0.0 0.15 11.0 0.0 2.9 3 0 0 3 3 3 0 Haspin like kinase domain FTA2 PF13095.6 EGO54593.1 - 0.21 11.2 1.2 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 adh_short_C2 PF13561.6 EGO54594.1 - 7.2e-63 212.3 0.9 9.5e-63 211.9 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO54594.1 - 1.3e-50 171.6 0.8 1.9e-50 171.1 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO54594.1 - 9.9e-11 41.9 0.3 1.5e-10 41.3 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO54594.1 - 7.4e-05 22.3 0.1 0.00025 20.6 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.22 EGO54594.1 - 0.0061 16.6 1.3 0.024 14.7 0.1 2.5 3 0 0 3 3 3 1 PA domain GDP_Man_Dehyd PF16363.5 EGO54594.1 - 0.018 14.4 0.1 0.043 13.2 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGO54594.1 - 0.021 14.0 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ARID PF01388.21 EGO54595.1 - 4.4e-18 65.7 0.5 1.2e-17 64.3 0.1 2.0 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 EGO54595.1 - 0.017 15.7 0.0 0.033 14.8 0.0 1.4 1 0 0 1 1 1 0 RFX DNA-binding domain SEN1_N PF12726.7 EGO54595.1 - 0.072 11.3 0.1 0.11 10.7 0.1 1.2 1 0 0 1 1 1 0 SEN1 N terminal SelR PF01641.18 EGO54597.1 - 3.4e-49 166.0 0.2 3.9e-49 165.7 0.2 1.0 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 EGO54597.1 - 0.0062 16.5 0.5 1.3 9.1 0.1 2.3 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_10 PF10058.9 EGO54597.1 - 0.02 14.6 0.1 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 EGO54597.1 - 0.021 15.1 0.3 0.047 13.9 0.3 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MCM_OB PF17207.3 EGO54597.1 - 0.08 12.8 0.2 0.15 11.9 0.0 1.4 2 0 0 2 2 2 0 MCM OB domain RIG-I_C-RD PF11648.8 EGO54597.1 - 0.13 12.5 0.0 0.41 10.9 0.0 1.8 2 0 0 2 2 2 0 C-terminal domain of RIG-I TF_Zn_Ribbon PF08271.12 EGO54597.1 - 0.14 11.7 1.0 0.77 9.3 0.2 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding ArfGap PF01412.18 EGO54598.1 - 2.8e-40 137.0 1.0 4.2e-40 136.5 1.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Synaptobrevin PF00957.21 EGO54599.1 - 0.0068 16.2 0.2 0.74 9.6 0.0 2.0 1 1 1 2 2 2 2 Synaptobrevin Ysc84 PF04366.12 EGO54600.1 - 7.8e-41 138.8 0.2 1.4e-40 138.0 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EGO54600.1 - 1.2e-12 47.2 0.2 3.3e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EGO54600.1 - 2.8e-11 43.1 0.0 4.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGO54600.1 - 1.9e-10 40.2 0.0 4.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Arrestin_C PF02752.22 EGO54601.1 - 3.5e-19 69.6 0.0 1.2e-18 67.9 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGO54601.1 - 7.1e-13 48.9 0.0 2.5e-12 47.1 0.0 1.9 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 EGO54601.1 - 0.0024 17.6 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like PH PF00169.29 EGO54602.1 - 0.025 15.1 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 PH domain Prominin PF05478.11 EGO54602.1 - 0.059 11.3 2.1 0.046 11.7 0.2 1.6 2 0 0 2 2 2 0 Prominin CK2S PF15011.6 EGO54602.1 - 0.29 11.0 3.1 3.8 7.4 0.0 2.9 2 1 1 3 3 3 0 Casein Kinase 2 substrate Apolipoprotein PF01442.18 EGO54602.1 - 1 9.2 7.4 0.63 9.9 2.9 2.1 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 EGO54602.1 - 2.1 8.5 9.0 9 6.5 1.4 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Alba PF01918.21 EGO54604.1 - 1.2e-12 47.5 0.0 2.4e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Alba DUF202 PF02656.15 EGO54605.1 - 6.4e-16 58.6 3.3 6.4e-16 58.6 3.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Tctex-1 PF03645.13 EGO54606.1 - 8.8e-36 122.3 0.1 1.1e-35 122.0 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family F-box-like PF12937.7 EGO54607.1 - 0.00093 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO54607.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.7 2 0 0 2 2 2 0 F-box domain CTP_transf_like PF01467.26 EGO54608.1 - 9.3e-31 106.9 0.0 1.6e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Fungal_trans PF04082.18 EGO54609.1 - 2.2e-11 43.3 0.1 5.7e-11 41.9 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain FTHFS PF01268.19 EGO54610.1 - 3.9e-257 853.9 0.0 8.7e-257 852.7 0.0 1.5 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EGO54610.1 - 6.3e-68 227.1 0.6 6.3e-68 227.1 0.6 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EGO54610.1 - 2.4e-38 130.9 0.2 5.7e-38 129.8 0.2 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Glyco_hydro_3_C PF01915.22 EGO54610.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain GTP_EFTU PF00009.27 EGO54610.1 - 0.16 11.5 1.9 0.33 10.5 0.1 2.2 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain WD40 PF00400.32 EGO54611.1 - 1.6e-25 88.8 4.1 6.2e-08 33.2 0.1 5.8 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO54611.1 - 2e-14 53.7 0.0 0.00024 21.3 0.0 4.7 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGO54611.1 - 0.00046 19.3 0.1 0.15 11.0 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region PALB2_WD40 PF16756.5 EGO54611.1 - 0.011 14.7 0.1 0.85 8.5 0.0 2.4 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 EGO54611.1 - 0.015 14.7 0.0 0.55 9.5 0.0 2.5 1 1 1 2 2 2 0 WD40-like domain Nup160 PF11715.8 EGO54611.1 - 0.034 12.8 0.0 0.063 11.9 0.0 1.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGO54611.1 - 0.047 12.4 0.0 0.14 10.9 0.0 1.7 1 1 0 1 1 1 0 Nup133 N terminal like SNF2_N PF00176.23 EGO54612.1 - 6.5e-76 255.3 0.2 1.3e-75 254.3 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EGO54612.1 - 2.5e-44 149.9 3.5 7.2e-44 148.5 3.5 1.9 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 EGO54612.1 - 3.6e-39 134.0 3.8 3.6e-39 134.0 3.8 3.5 3 0 0 3 3 2 1 HAND Helicase_C PF00271.31 EGO54612.1 - 9.3e-19 67.8 0.0 6.5e-18 65.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO54612.1 - 7.2e-12 45.6 0.3 4.2e-11 43.1 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGO54612.1 - 6.9e-06 25.4 0.0 3.3e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EGO54612.1 - 2.5e-05 24.1 0.0 9.6e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EGO54612.1 - 6e-05 22.8 0.0 0.00017 21.3 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Myb_DNA-binding PF00249.31 EGO54612.1 - 6.4e-05 23.1 0.1 0.52 10.5 0.0 3.3 2 1 0 2 2 2 2 Myb-like DNA-binding domain DUF1086 PF06461.11 EGO54612.1 - 0.0026 17.6 0.0 0.0084 16.0 0.0 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) DEAD_2 PF06733.15 EGO54612.1 - 0.081 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.6 EGO54612.1 - 0.084 12.9 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Occludin_ELL PF07303.13 EGO54612.1 - 0.17 12.6 3.5 0.55 11.0 3.5 1.9 1 0 0 1 1 1 0 Occludin homology domain NYD-SP28_assoc PF14775.6 EGO54612.1 - 0.19 11.8 1.6 0.88 9.7 1.1 2.5 2 0 0 2 2 1 0 Sperm tail C-terminal domain DUF4588 PF15251.6 EGO54613.1 - 1.1e-05 25.3 7.9 7.9e-05 22.5 7.9 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) CCSAP PF15748.5 EGO54613.1 - 0.0019 18.4 4.7 0.0028 17.9 4.7 1.2 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated zf-RING_UBOX PF13445.6 EGO54619.1 - 3.2e-07 30.2 3.1 3.2e-07 30.2 3.1 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGO54619.1 - 5.4e-07 29.4 7.0 1e-06 28.5 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO54619.1 - 4.5e-06 26.5 3.8 9e-06 25.5 3.8 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGO54619.1 - 3.4e-05 23.6 5.8 6.5e-05 22.7 2.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO54619.1 - 3.5e-05 23.6 7.6 0.00014 21.6 7.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO54619.1 - 4.5e-05 23.7 7.6 0.00013 22.2 7.6 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 EGO54619.1 - 0.0005 20.2 2.8 0.0005 20.2 2.8 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EGO54619.1 - 0.027 14.3 4.4 0.049 13.4 4.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 EGO54619.1 - 0.097 12.6 10.5 0.56 10.1 6.2 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EGO54619.1 - 0.29 11.3 5.0 0.15 12.2 2.2 1.8 1 1 1 2 2 2 0 zinc RING finger of MSL2 Ribosomal_60s PF00428.19 EGO54619.1 - 3.8 8.2 6.6 2.1 9.0 1.5 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-rbx1 PF12678.7 EGO54619.1 - 4.3 7.7 7.4 15 6.0 7.4 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain AMPK1_CBM PF16561.5 EGO54620.1 - 1.1e-13 51.2 0.3 1.6e-06 28.2 0.1 2.5 2 0 0 2 2 2 2 Glycogen recognition site of AMP-activated protein kinase NAD_binding_6 PF08030.12 EGO54621.1 - 3e-20 72.9 0.0 5.8e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGO54621.1 - 5.8e-11 42.4 0.0 1.3e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EGO54621.1 - 0.00082 19.5 0.9 0.0017 18.5 0.9 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EGO54621.1 - 0.0012 19.5 0.0 0.041 14.5 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain RTA1 PF04479.13 EGO54624.1 - 1.2e-22 80.6 10.1 8.7e-22 77.7 10.1 1.9 1 1 0 1 1 1 1 RTA1 like protein PGAP1 PF07819.13 EGO54625.1 - 8.1e-08 32.3 0.4 2.1e-07 30.9 0.4 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 EGO54625.1 - 5.4e-07 29.5 0.1 3.8e-06 26.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 EGO54625.1 - 9.8e-07 28.9 0.0 1.9e-06 27.9 0.0 1.5 2 0 0 2 2 2 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EGO54625.1 - 6.5e-06 25.8 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EGO54625.1 - 4.2e-05 24.3 0.1 5.6e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 EGO54625.1 - 0.00017 20.9 0.0 0.00028 20.2 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 EGO54625.1 - 0.00046 20.4 0.0 0.00067 19.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF900 PF05990.12 EGO54625.1 - 0.0083 15.7 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 EGO54625.1 - 0.0093 15.3 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.18 EGO54625.1 - 0.013 15.1 0.0 0.17 11.4 0.0 2.3 3 0 0 3 3 3 0 Lipase (class 2) Ser_hydrolase PF06821.13 EGO54625.1 - 0.05 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Hydrolase_4 PF12146.8 EGO54625.1 - 0.063 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF4965 PF16335.5 EGO54627.1 - 3.2e-73 245.1 0.0 6.5e-73 244.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EGO54627.1 - 1.1e-62 211.8 5.7 2.2e-61 207.5 5.7 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 EGO54627.1 - 1.6e-51 175.1 0.6 6.2e-51 173.2 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EGO54627.1 - 1.7e-09 37.1 1.2 4.1e-09 35.9 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4964) DUF4140 PF13600.6 EGO54627.1 - 0.093 13.2 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) UPF0160 PF03690.13 EGO54628.1 - 2.5e-132 441.3 0.0 2.8e-132 441.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ino80_Iec3 PF14612.6 EGO54629.1 - 9.5e-59 199.9 3.1 6.1e-30 105.6 2.3 2.2 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling Iso_dh PF00180.20 EGO54630.1 - 9.3e-71 238.8 0.0 1.1e-70 238.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3364 PF11844.8 EGO54630.1 - 1.8 8.9 3.9 6.5 7.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3364) Not3 PF04065.15 EGO54632.1 - 4.1e-90 301.2 19.3 6.4e-90 300.6 19.3 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EGO54632.1 - 7e-42 142.6 13.1 1.7e-41 141.4 13.1 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family ABC_tran_CTD PF16326.5 EGO54632.1 - 0.0046 17.2 3.0 0.0046 17.2 3.0 3.5 2 1 0 2 2 1 1 ABC transporter C-terminal domain DUF1192 PF06698.11 EGO54632.1 - 0.0085 16.1 3.0 0.019 15.0 0.9 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Syntaxin_2 PF14523.6 EGO54632.1 - 0.022 15.1 1.8 0.022 15.1 1.8 2.5 3 0 0 3 3 3 0 Syntaxin-like protein DUF2373 PF10180.9 EGO54632.1 - 0.028 14.3 3.3 0.063 13.1 3.3 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.13 EGO54632.1 - 0.089 13.3 7.5 0.46 11.0 0.8 2.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Mu-like_Pro PF10123.9 EGO54632.1 - 0.41 10.2 9.1 1 8.8 9.1 1.7 1 0 0 1 1 1 0 Mu-like prophage I protein HR1 PF02185.16 EGO54632.1 - 0.43 10.7 8.5 0.52 10.5 1.2 2.8 2 0 0 2 2 2 0 Hr1 repeat Sec5 PF15469.6 EGO54632.1 - 0.69 9.7 6.6 0.6 9.9 0.8 2.4 2 0 0 2 2 2 0 Exocyst complex component Sec5 CorA PF01544.18 EGO54632.1 - 0.73 9.1 5.4 0.23 10.7 0.9 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF4140 PF13600.6 EGO54632.1 - 4.6 7.7 6.5 15 6.1 0.7 3.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Tyr_Deacylase PF02580.16 EGO54633.1 - 4e-41 140.9 0.0 6e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DMRL_synthase PF00885.19 EGO54633.1 - 0.17 11.7 1.9 0.38 10.6 0.4 2.1 2 1 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase Androgen_recep PF02166.16 EGO54633.1 - 1.4 7.7 11.0 2 7.2 11.0 1.1 1 0 0 1 1 1 0 Androgen receptor Pro_isomerase PF00160.21 EGO54634.1 - 8.8e-50 169.1 0.2 1.4e-49 168.4 0.2 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EGO54634.1 - 1.2e-06 28.2 2.5 0.0025 17.8 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGO54634.1 - 6.1e-06 25.8 1.4 0.0079 16.0 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGO54634.1 - 0.00018 21.7 0.7 0.01 16.1 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGO54634.1 - 0.0027 17.8 0.2 0.0091 16.1 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGO54634.1 - 0.0081 15.8 1.1 0.53 10.0 0.1 3.2 3 0 0 3 3 3 1 TPR repeat TPR_6 PF13174.6 EGO54634.1 - 0.041 14.5 0.7 0.18 12.5 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGO54634.1 - 0.35 11.8 2.8 0.45 11.5 0.4 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RasGAP PF00616.19 EGO54635.1 - 4.9e-32 111.3 0.0 3.7e-22 79.1 0.0 2.6 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EGO54635.1 - 0.00056 20.2 0.0 0.0018 18.6 0.0 1.9 1 1 0 1 1 1 1 C2 domain Ureidogly_lyase PF04115.12 EGO54637.1 - 8.2e-45 152.9 0.0 9.4e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase MFS_1 PF07690.16 EGO54638.1 - 0.095 11.6 11.1 0.031 13.2 3.3 2.8 2 1 0 2 2 2 0 Major Facilitator Superfamily ODAPH PF15848.5 EGO54639.1 - 0.037 14.5 2.0 0.059 13.8 2.0 1.3 1 0 0 1 1 1 0 Odontogenesis associated phosphoprotein bZIP_1 PF00170.21 EGO54640.1 - 5.2 7.2 17.4 2.5 8.2 7.7 2.1 1 1 1 2 2 2 0 bZIP transcription factor PseudoU_synth_2 PF00849.22 EGO54641.1 - 6.9e-31 107.5 0.0 1e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ub-Mut7C PF14451.6 EGO54641.1 - 0.0019 18.0 0.1 0.0041 16.9 0.1 1.5 1 0 0 1 1 1 1 Mut7-C ubiquitin TGS PF02824.21 EGO54641.1 - 0.057 13.5 0.2 0.21 11.7 0.1 2.0 2 0 0 2 2 2 0 TGS domain Auto_anti-p27 PF06677.12 EGO54641.1 - 0.078 13.1 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) S4 PF01479.25 EGO54641.1 - 0.16 11.7 0.6 0.58 9.9 0.1 2.1 2 0 0 2 2 2 0 S4 domain Viral_DNA_bp PF00747.17 EGO54642.1 - 0.37 7.9 2.0 0.4 7.8 2.0 1.0 1 0 0 1 1 1 0 ssDNA binding protein IRF-2BP1_2 PF11261.8 EGO54644.1 - 0.14 11.7 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger RdRP PF05183.12 EGO54648.1 - 0.26 9.9 1.3 0.32 9.6 1.3 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase Importin_rep_4 PF18808.1 EGO54648.1 - 0.82 10.0 6.5 2.5 8.5 4.3 2.2 2 0 0 2 2 2 0 Importin repeat Sas10_Utp3 PF04000.15 EGO54651.1 - 0.17 12.6 0.8 0.22 12.1 0.8 1.3 1 0 0 1 1 1 0 Sas10/Utp3/C1D family ketoacyl-synt PF00109.26 EGO54652.1 - 5.7e-74 248.9 0.6 9.5e-74 248.2 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EGO54652.1 - 1.6e-55 187.8 1.0 5.4e-55 186.1 0.2 2.4 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 EGO54652.1 - 6.7e-53 180.3 0.0 1.1e-52 179.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EGO54652.1 - 1.5e-43 149.2 0.0 2.7e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EGO54652.1 - 4.3e-38 130.0 0.1 1.8e-37 127.9 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGO54652.1 - 9.7e-17 61.4 0.0 2.2e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EGO54652.1 - 3.1e-14 52.9 0.1 2.5e-13 49.9 0.1 2.5 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 EGO54652.1 - 1.2e-12 49.0 0.0 3.9e-12 47.4 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGO54652.1 - 4.5e-12 46.1 0.4 1.5e-11 44.3 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 EGO54652.1 - 4.3e-08 33.0 0.0 1.3e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 EGO54652.1 - 1e-05 25.3 0.0 2.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGO54652.1 - 5.7e-05 23.4 2.1 0.0001 22.6 0.8 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EGO54652.1 - 0.00023 20.6 0.2 0.00044 19.7 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EGO54652.1 - 0.047 13.5 0.1 0.15 11.9 0.1 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FSH1 PF03959.13 EGO54654.1 - 4.5e-30 104.9 0.0 9.5e-30 103.8 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PE-PPE PF08237.11 EGO54654.1 - 0.21 11.1 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain ABC_membrane PF00664.23 EGO54655.1 - 4.8e-49 167.4 19.1 2.4e-37 129.1 6.3 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EGO54655.1 - 6.2e-44 149.8 0.0 5.4e-31 107.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGO54655.1 - 5.9e-14 52.0 0.9 1.5e-05 24.6 0.2 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EGO54655.1 - 1.9e-05 24.8 0.8 0.057 13.7 0.3 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 EGO54655.1 - 0.00013 22.3 0.0 0.0032 17.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EGO54655.1 - 0.00015 21.7 0.1 0.069 12.9 0.0 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EGO54655.1 - 0.001 19.5 0.2 1.7 9.1 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGO54655.1 - 0.0012 18.8 0.0 0.0076 16.2 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 EGO54655.1 - 0.0016 18.8 0.1 0.0068 16.8 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.9 EGO54655.1 - 0.0097 14.7 0.0 0.039 12.8 0.0 1.9 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_30 PF13604.6 EGO54655.1 - 0.012 15.4 0.2 0.11 12.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain MoaE PF02391.17 EGO54655.1 - 0.026 14.8 0.4 1.7 8.9 0.1 2.6 2 0 0 2 2 2 0 MoaE protein AAA_5 PF07728.14 EGO54655.1 - 0.074 13.0 0.0 0.48 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGO54655.1 - 0.08 13.5 0.0 0.21 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dala_Dala_lig_N PF01820.21 EGO54655.1 - 0.082 13.4 0.0 0.23 11.9 0.0 1.9 2 0 0 2 2 1 0 D-ala D-ala ligase N-terminus AAA_25 PF13481.6 EGO54655.1 - 0.09 12.3 0.0 0.53 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGO54655.1 - 0.092 12.8 0.0 0.71 9.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 EGO54655.1 - 0.21 11.2 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Glyco_hydro_71 PF03659.14 EGO54656.1 - 4.4e-128 427.3 4.3 5.2e-128 427.0 4.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Aldo_ket_red PF00248.21 EGO54657.1 - 3.5e-71 239.8 0.0 4.2e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fmp27_SW PF10305.9 EGO54658.1 - 0.34 11.6 3.7 1.6 9.5 0.9 2.8 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Ndc1_Nup PF09531.10 EGO54658.1 - 2.3 6.8 7.9 3.1 6.4 7.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4834 PF16118.5 EGO54658.1 - 3.4 8.7 5.5 8.1 7.5 5.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Band_3_cyto PF07565.13 EGO54658.1 - 4.1 7.1 10.5 6.4 6.5 9.8 1.7 1 1 1 2 2 2 0 Band 3 cytoplasmic domain Presenilin PF01080.17 EGO54658.1 - 7.4 5.2 6.5 10 4.8 6.5 1.2 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 EGO54658.1 - 8 6.0 18.7 12 5.4 18.7 1.2 1 0 0 1 1 1 0 Spt20 family Cupin_2 PF07883.11 EGO54659.1 - 1.7e-14 53.2 0.0 2.5e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EGO54659.1 - 3.1e-08 33.6 0.0 4.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EGO54659.1 - 4.1e-08 33.0 0.0 5.4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EGO54659.1 - 0.00015 21.4 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.7 EGO54659.1 - 0.00024 20.9 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.18 EGO54659.1 - 0.0017 18.2 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase ARD PF03079.14 EGO54659.1 - 0.0096 16.1 0.1 0.015 15.5 0.1 1.4 1 0 0 1 1 1 1 ARD/ARD' family CENP-C_C PF11699.8 EGO54659.1 - 0.012 15.8 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like EutQ PF06249.12 EGO54659.1 - 0.035 13.9 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Pkinase PF00069.25 EGO54660.1 - 4.1e-26 91.9 0.0 1.4e-25 90.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO54660.1 - 7.7e-15 54.9 0.0 5.9e-14 52.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase FGGY_C PF02782.16 EGO54662.1 - 6.4e-71 238.2 1.0 1.2e-70 237.2 1.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGO54662.1 - 5.6e-48 163.6 0.0 9.3e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain NTP_transferase PF00483.23 EGO54663.1 - 5.4e-54 183.4 0.0 1.2e-53 182.2 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 EGO54663.1 - 1e-17 63.0 18.3 1.3e-10 40.5 1.8 3.4 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EGO54663.1 - 4.8e-10 40.0 0.0 6.6e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EGO54663.1 - 3.2e-07 30.0 6.7 2.3e-06 27.2 0.5 3.2 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EGO54663.1 - 0.00029 19.1 0.1 0.00081 17.7 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) dsrm PF00035.26 EGO54665.1 - 0.00083 20.0 0.0 0.0017 19.0 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EGO54665.1 - 0.0021 18.3 0.0 0.004 17.4 0.0 1.5 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 CCDC24 PF15669.5 EGO54665.1 - 0.15 11.9 0.3 0.16 11.8 0.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Harakiri PF15196.6 EGO54666.1 - 0.058 13.9 0.1 0.058 13.9 0.1 2.5 2 1 0 2 2 2 0 Activator of apoptosis harakiri Prenyltrans PF00432.21 EGO54667.1 - 1.1e-35 121.0 18.4 3.9e-10 39.3 0.2 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EGO54667.1 - 0.01 15.0 0.2 0.023 13.8 0.2 1.5 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EGO54667.1 - 0.014 14.5 0.1 2.8 7.0 0.0 2.2 1 1 1 2 2 2 0 Squalene-hopene cyclase N-terminal domain RelE PF06296.12 EGO54667.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 RelE toxin of RelE / RelB toxin-antitoxin system Zn_clus PF00172.18 EGO54670.1 - 0.0039 17.3 7.7 0.0083 16.2 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ubiquitin PF00240.23 EGO54671.1 - 9.4e-137 445.0 23.0 9.5e-34 115.0 0.9 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 EGO54671.1 - 1.9e-63 210.2 24.0 1.9e-15 56.4 1.0 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGO54671.1 - 4.7e-24 84.7 12.3 0.00016 22.0 0.2 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 EGO54671.1 - 2e-16 59.7 5.8 0.017 15.0 0.1 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGO54671.1 - 2.5e-15 56.5 4.5 0.054 13.6 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGO54671.1 - 3.3e-15 56.5 1.6 0.085 13.4 0.0 4.1 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGO54671.1 - 1.4e-14 54.2 10.7 0.025 14.9 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 EGO54671.1 - 9.8e-11 41.8 0.5 0.64 9.8 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EGO54671.1 - 1.8e-07 31.1 25.7 11 6.2 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain DUF3861 PF12977.7 EGO54671.1 - 7.9e-07 29.2 3.9 6.9 6.9 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 EGO54671.1 - 7.8e-06 26.2 0.0 30 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 EGO54671.1 - 1.1e-05 24.9 0.8 2.6 7.3 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase TmoB PF06234.12 EGO54671.1 - 1.7e-05 24.8 0.0 32 4.7 0.0 4.8 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) DUF493 PF04359.14 EGO54671.1 - 3.3e-05 24.4 0.1 44 4.8 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Big_7 PF17957.1 EGO54671.1 - 8.7e-05 23.2 0.1 63 4.4 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain Big_3_3 PF13750.6 EGO54671.1 - 9.1e-05 22.2 0.1 31 4.2 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) DUF1940 PF09155.10 EGO54671.1 - 0.00015 21.9 5.5 18 5.4 0.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1940) UDP-g_GGTase PF06427.11 EGO54671.1 - 0.00018 21.6 4.7 7.1 6.8 0.1 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase ACT_5 PF13710.6 EGO54671.1 - 0.00019 21.2 6.5 15 5.5 0.1 4.3 4 0 0 4 4 4 0 ACT domain Raf1_HTH PF18579.1 EGO54671.1 - 0.0002 21.0 1.4 37 4.1 0.0 4.2 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain DUF969 PF06149.12 EGO54671.1 - 0.00042 19.8 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 EGO54671.1 - 0.0013 19.2 1.9 85 3.8 0.0 4.3 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 EGO54671.1 - 0.003 17.6 0.0 91 3.3 0.0 4.9 4 0 0 4 4 4 0 ORF11CD3 domain Baculo_p48 PF04878.13 EGO54671.1 - 0.007 15.4 0.1 24 3.7 0.0 3.2 4 0 0 4 4 4 0 Baculovirus P48 protein ProRS-C_2 PF09181.10 EGO54671.1 - 0.031 14.4 6.3 70 3.7 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 EGO54671.1 - 0.14 12.3 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif PI3K_p85B PF02192.16 EGO54671.1 - 0.15 11.8 11.0 37 4.2 0.1 4.3 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Myosin_N PF02736.19 EGO54671.1 - 0.31 10.9 6.3 1.1e+02 2.8 0.0 5.0 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 EGO54671.1 - 1.7 8.3 3.5 2.4e+02 1.4 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 Phage_sheath_1N PF17481.2 EGO54671.1 - 2.4 8.7 9.2 1.5e+02 2.9 0.1 3.9 1 1 0 2 2 2 0 Phage tail sheath protein beta-sandwich domain Plexin_cytopl PF08337.12 EGO54671.1 - 3.1 6.4 20.5 9.2 4.8 0.6 5.0 5 3 0 5 5 5 0 Plexin cytoplasmic RasGAP domain BRAP2 PF07576.12 EGO54672.1 - 2.4e-29 101.5 0.0 5.9e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EGO54672.1 - 2.5e-18 66.1 5.2 1.1e-17 64.1 5.2 2.2 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EGO54672.1 - 3.3e-07 30.5 9.1 3.3e-07 30.5 9.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO54672.1 - 1.2e-05 25.0 9.6 2.8e-05 23.9 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGO54672.1 - 3.6e-05 23.4 5.0 0.00013 21.6 5.0 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EGO54672.1 - 0.0004 20.3 7.3 0.0004 20.3 7.3 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO54672.1 - 0.00082 19.2 8.4 0.0024 17.7 8.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO54672.1 - 0.0031 17.5 3.2 0.0031 17.5 3.2 2.8 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGO54672.1 - 0.006 16.4 6.2 0.006 16.4 6.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGO54672.1 - 0.0078 16.5 6.5 0.0078 16.5 6.5 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-UBP_var PF17807.1 EGO54672.1 - 1.7 8.5 6.8 0.52 10.1 0.3 2.8 2 1 0 2 2 2 0 Variant UBP zinc finger Fungal_trans PF04082.18 EGO54673.1 - 9.5e-21 74.0 0.1 3.1e-20 72.3 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO54673.1 - 0.024 14.8 4.8 0.052 13.7 4.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM199X PF15814.5 EGO54673.1 - 0.43 9.6 6.6 0.81 8.7 6.6 1.4 1 0 0 1 1 1 0 Protein family FAM199X Acetyltransf_1 PF00583.25 EGO54674.1 - 1.4e-10 41.4 0.0 3.3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO54674.1 - 6e-10 39.1 0.0 1.9e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 EGO54674.1 - 2.4e-08 34.0 8.1 5.2e-08 32.9 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_7 PF13508.7 EGO54674.1 - 1.3e-07 32.0 0.0 5.8e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO54674.1 - 0.00019 21.4 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Fungal_trans_2 PF11951.8 EGO54674.1 - 0.0059 15.5 2.7 0.013 14.4 2.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Acetyltransf_9 PF13527.7 EGO54674.1 - 0.095 12.8 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.25 EGO54676.1 - 2.7e-06 27.0 0.0 0.0054 16.2 0.0 3.6 3 1 0 3 3 3 2 short chain dehydrogenase MFS_1 PF07690.16 EGO54677.1 - 4.7e-17 61.9 38.8 4.7e-17 61.9 38.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EGO54677.1 - 0.0023 16.8 7.0 0.024 13.5 0.8 2.4 1 1 1 2 2 2 2 MFS_1 like family DUF3487 PF11990.8 EGO54677.1 - 3.2 7.7 10.1 14 5.6 0.6 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) UCR_hinge PF02320.16 EGO54678.1 - 5.8e-28 96.9 7.4 5.8e-28 96.9 7.4 1.7 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein Myc_N PF01056.18 EGO54678.1 - 0.06 13.2 9.1 0.066 13.1 9.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Sigma70_ner PF04546.13 EGO54678.1 - 0.12 12.2 8.8 0.17 11.7 8.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RR_TM4-6 PF06459.12 EGO54678.1 - 0.46 10.3 9.7 0.52 10.1 9.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TLP-20 PF06088.11 EGO54678.1 - 0.64 9.9 3.9 0.76 9.6 3.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Tim54 PF11711.8 EGO54678.1 - 0.65 8.7 8.6 0.68 8.7 8.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pox_Ag35 PF03286.14 EGO54678.1 - 0.67 9.7 13.0 0.81 9.4 13.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 EGO54678.1 - 0.95 7.6 11.2 0.97 7.6 11.2 1.0 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 EGO54678.1 - 1.7 7.5 4.0 1.8 7.5 4.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4820 PF16091.5 EGO54678.1 - 2.3 7.5 7.6 2.9 7.2 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4746 PF15928.5 EGO54678.1 - 2.3 7.5 14.4 2.5 7.4 14.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Kei1 PF08552.11 EGO54678.1 - 3 7.7 3.8 3.7 7.4 3.8 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SAPS PF04499.15 EGO54678.1 - 3.2 6.4 5.2 3.2 6.5 5.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 EGO54678.1 - 3.7 6.2 6.4 4.2 6.0 6.4 1.0 1 0 0 1 1 1 0 Presenilin AIF_C PF14721.6 EGO54678.1 - 5.9 7.3 5.6 8 6.8 5.6 1.3 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Cytomega_UL84 PF06284.11 EGO54678.1 - 7.5 4.9 13.0 8.5 4.7 13.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein TRAP_alpha PF03896.16 EGO54678.1 - 7.9 5.6 8.9 9.4 5.3 8.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Drf_GBD PF06371.13 EGO54680.1 - 5.2e-14 52.2 3.1 1.3e-08 34.6 0.0 2.9 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Suc_Fer-like PF06999.12 EGO54681.1 - 1.5e-69 233.8 0.0 1.8e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Fer4_13 PF13370.6 EGO54681.1 - 0.015 15.8 0.1 0.042 14.4 0.1 1.8 1 0 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I Acyltransferase PF01553.21 EGO54682.1 - 1.5e-09 37.6 0.0 9.1e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Fapy_DNA_glyco PF01149.24 EGO54683.1 - 2.2e-35 121.8 0.0 5.1e-35 120.6 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EGO54683.1 - 3.4e-22 78.2 0.0 7e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 EGO54683.1 - 0.0014 17.5 0.0 0.0025 16.7 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.22 EGO54683.1 - 0.093 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S13/S18 DHBP_synthase PF00926.19 EGO54685.1 - 7.2e-83 276.8 0.0 8.4e-83 276.6 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Methyltransf_23 PF13489.6 EGO54686.1 - 1.8e-21 76.7 0.0 2.6e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO54686.1 - 5.8e-18 65.3 0.0 9.7e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO54686.1 - 7.2e-16 58.3 0.0 9.5e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO54686.1 - 7.5e-15 55.4 0.0 1.3e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO54686.1 - 1.5e-14 54.5 0.0 3.3e-14 53.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 EGO54686.1 - 5.1e-07 29.4 0.0 7.3e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EGO54686.1 - 0.00013 21.3 0.1 0.0007 19.0 0.1 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EGO54686.1 - 0.0023 16.9 0.0 0.0034 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 EGO54686.1 - 0.082 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 EGO54686.1 - 0.15 11.2 0.0 0.33 10.0 0.0 1.5 1 1 0 1 1 1 0 DREV methyltransferase Methyltransf_18 PF12847.7 EGO54686.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S10 PF00450.22 EGO54687.1 - 1.7e-71 241.8 0.0 5.5e-71 240.2 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase DUF4642 PF15484.6 EGO54687.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) RXT2_N PF08595.11 EGO54688.1 - 5.5e-46 156.4 0.0 5.5e-46 156.4 0.0 2.5 2 1 0 2 2 2 1 RXT2-like, N-terminal Tyrosinase PF00264.20 EGO54689.1 - 1.8e-42 146.1 6.4 1.9e-42 146.1 0.0 2.5 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EGO54689.1 - 0.013 16.1 0.0 0.047 14.3 0.0 1.9 2 0 0 2 2 2 0 Tyosinase C-terminal domain Macoilin PF09726.9 EGO54689.1 - 2.1 6.8 9.2 2.7 6.4 9.2 1.1 1 0 0 1 1 1 0 Macoilin family DHDPS PF00701.22 EGO54690.1 - 5.7e-37 127.0 0.0 7.8e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF2270 PF10028.9 EGO54692.1 - 0.15 11.6 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) Glyco_hydro_16 PF00722.21 EGO54693.1 - 1.5e-46 158.1 2.0 1.5e-46 158.1 2.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 SIR2 PF02146.17 EGO54695.1 - 1.6e-41 142.2 0.0 3.4e-41 141.1 0.0 1.5 1 1 0 1 1 1 1 Sir2 family Dfp1_Him1_M PF08630.10 EGO54697.1 - 1.1e-44 151.7 0.0 3.3e-44 150.1 0.0 1.9 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 EGO54697.1 - 1.3e-21 76.4 0.1 2.1e-21 75.8 0.1 1.3 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 EGO54697.1 - 0.0011 18.9 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EGO54697.1 - 0.023 15.0 0.0 0.1 13.0 0.0 2.0 1 1 1 2 2 2 0 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGO54697.1 - 0.16 12.4 0.1 0.48 10.9 0.0 1.8 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Peptidase_M24 PF00557.24 EGO54698.1 - 2.3e-49 167.9 0.0 3.3e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGO54698.1 - 3.4e-35 120.5 0.0 5.2e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HLH PF00010.26 EGO54699.1 - 2.3e-17 62.7 0.4 1.7e-16 59.9 0.0 2.5 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Paramyxo_P PF01806.17 EGO54699.1 - 0.62 9.5 3.2 1.9 7.8 0.1 2.2 2 0 0 2 2 2 0 Paramyxovirinae P phosphoprotein C-terminal region Med3 PF11593.8 EGO54699.1 - 1.2 8.3 15.4 1.6 7.8 3.9 2.3 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal APG12 PF04110.13 EGO54700.1 - 1.6e-24 86.1 0.0 2e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EGO54700.1 - 0.00029 21.0 0.0 0.00036 20.7 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.15 EGO54701.1 - 2.9e-108 361.2 0.6 3.6e-108 360.9 0.6 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EGO54701.1 - 1.8e-08 34.1 1.8 6.9e-08 32.2 1.9 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 EGO54701.1 - 0.0017 17.4 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4861) NanE PF04131.14 EGO54701.1 - 0.094 11.9 0.3 5.4 6.2 0.2 2.7 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Ntox43 PF15537.6 EGO54702.1 - 0.041 13.9 0.0 0.042 13.9 0.0 1.0 1 0 0 1 1 1 0 Bacterial toxin 43 UQ_con PF00179.26 EGO54703.1 - 2.2e-37 127.8 0.1 2.7e-37 127.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pectinesterase PF01095.19 EGO54704.1 - 8.4e-48 162.6 2.1 1.1e-47 162.2 2.1 1.0 1 0 0 1 1 1 1 Pectinesterase Glyco_hydro_61 PF03443.14 EGO54705.1 - 4.5e-71 239.0 0.3 7.5e-71 238.3 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Med3 PF11593.8 EGO54705.1 - 0.31 10.2 23.9 0.46 9.6 23.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CDC27 PF09507.10 EGO54705.1 - 1.2 8.4 3.6 1.6 8.0 3.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 YTH PF04146.15 EGO54706.1 - 2e-38 131.9 1.2 2e-38 131.9 1.2 3.4 3 2 0 3 3 3 1 YT521-B-like domain p450 PF00067.22 EGO54707.1 - 8.9e-26 90.6 0.0 1.1e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DRMBL PF07522.14 EGO54708.1 - 1.3e-05 25.3 0.0 3.2e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Glyco_hydro_43 PF04616.14 EGO54709.1 - 0.016 14.5 1.1 0.026 13.8 1.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 EGO54709.1 - 0.043 13.4 0.1 0.2 11.2 0.0 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Exo_endo_phos_2 PF14529.6 EGO54709.1 - 0.045 13.6 2.3 1.6 8.6 0.2 2.4 1 1 1 2 2 2 0 Endonuclease-reverse transcriptase Velvet PF11754.8 EGO54710.1 - 1e-43 150.1 7.2 1.4e-32 113.6 0.2 2.5 2 1 1 3 3 3 2 Velvet factor DUF572 PF04502.13 EGO54714.1 - 9.7e-75 252.2 0.0 1.1e-74 252.0 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF5346 PF17281.2 EGO54714.1 - 0.0071 16.4 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5346) DUF4472 PF14739.6 EGO54714.1 - 0.18 12.5 4.1 0.076 13.8 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) GBP_C PF02841.14 EGO54714.1 - 0.28 10.5 6.0 0.48 9.8 6.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Mannosyl_trans2 PF04188.13 EGO54715.1 - 4.7e-51 174.5 0.0 9.9e-51 173.4 0.0 1.6 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) V-SNARE PF05008.15 EGO54716.1 - 4.6e-24 84.6 3.8 4.6e-24 84.6 3.8 1.7 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EGO54716.1 - 1.8e-16 60.1 0.8 1.8e-16 60.1 0.8 2.5 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.11 EGO54716.1 - 0.0055 14.7 3.9 0.0042 15.1 2.2 1.5 1 1 0 1 1 1 1 Prominin Sec20 PF03908.13 EGO54716.1 - 0.0091 15.9 1.6 0.013 15.4 0.5 1.9 2 0 0 2 2 2 1 Sec20 Synaptobrevin PF00957.21 EGO54716.1 - 0.096 12.5 2.4 0.26 11.1 2.1 2.0 1 1 1 2 2 2 0 Synaptobrevin Birna_RdRp PF04197.12 EGO54716.1 - 0.1 10.9 0.1 0.12 10.7 0.1 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) SNARE PF05739.19 EGO54716.1 - 0.15 12.1 0.4 0.15 12.1 0.4 2.1 3 0 0 3 3 3 0 SNARE domain Use1 PF09753.9 EGO54716.1 - 0.26 11.0 7.4 32 4.1 7.3 2.7 1 1 0 1 1 1 0 Membrane fusion protein Use1 Fusion_gly PF00523.18 EGO54716.1 - 0.77 7.9 6.9 0.21 9.8 1.3 2.2 3 0 0 3 3 3 0 Fusion glycoprotein F0 HET PF06985.11 EGO54718.1 - 5.2e-28 98.2 0.0 7.7e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_2_C PF02836.17 EGO54719.1 - 6.6e-104 347.2 0.0 1e-103 346.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 EGO54719.1 - 5.6e-59 199.7 0.1 9.5e-59 198.9 0.1 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 EGO54719.1 - 1.7e-37 128.9 0.2 3.4e-37 127.9 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 EGO54719.1 - 2.6e-17 63.1 0.0 7.9e-17 61.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 EGO54719.1 - 4.9e-09 36.8 0.0 1.6e-08 35.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 EGO54719.1 - 1.5e-05 25.5 0.0 4.3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Sortilin-Vps10 PF15902.5 EGO54720.1 - 1.1e-20 73.8 10.4 2.9e-07 29.7 0.0 5.9 4 2 2 6 6 6 5 Sortilin, neurotensin receptor 3, CBM_1 PF00734.18 EGO54720.1 - 3e-13 49.4 11.4 9e-13 47.9 11.4 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.20 EGO54720.1 - 2.8e-12 44.7 28.4 1.2 9.4 0.1 10.4 9 0 0 9 9 9 7 BNR/Asp-box repeat BNR_6 PF15899.5 EGO54720.1 - 1.1e-06 28.1 9.2 0.7 10.1 0.1 7.7 9 0 0 9 9 9 2 BNR-Asp box repeat YL1 PF05764.13 EGO54721.1 - 0.00027 21.1 2.3 0.00027 21.1 2.3 3.0 2 1 0 2 2 2 1 YL1 nuclear protein TFIIA PF03153.13 EGO54721.1 - 0.00081 19.5 2.5 0.00081 19.5 2.5 1.7 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 EGO54721.1 - 2 6.6 4.0 3.3 5.9 4.0 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF829 PF05705.14 EGO54722.1 - 4.2e-39 134.9 0.1 2.2e-36 126.0 0.1 3.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) SesA PF17107.5 EGO54723.1 - 0.13 12.4 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4448 PF14610.6 EGO54724.1 - 0.09 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.10 EGO54724.1 - 0.23 10.9 1.4 0.57 9.6 1.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LAMTOR PF15454.6 EGO54725.1 - 4.9e-09 36.7 0.5 7.6e-09 36.1 0.5 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator RPEL PF02755.15 EGO54728.1 - 0.00053 19.6 0.5 0.0019 17.8 0.0 2.0 2 0 0 2 2 2 1 RPEL repeat CT47 PF15623.6 EGO54729.1 - 4.6 7.0 17.1 5.1 6.9 17.1 1.0 1 0 0 1 1 1 0 Cancer/testis gene family 47 VWA_N2 PF16164.5 EGO54729.1 - 10 6.4 11.3 3.4 7.9 7.9 1.8 1 1 1 2 2 2 0 VWA N-terminal zf-C2H2_jaz PF12171.8 EGO54730.1 - 0.00026 21.2 0.0 0.00043 20.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding TFIIA PF03153.13 EGO54730.1 - 0.013 15.5 21.4 0.019 15.0 21.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MRNIP PF15749.5 EGO54730.1 - 0.034 14.9 0.4 0.034 14.9 0.4 2.5 3 0 0 3 3 3 0 MRN-interacting protein UPF0449 PF15136.6 EGO54730.1 - 0.044 14.3 0.3 0.044 14.3 0.3 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 zf-C2H2_3rep PF18868.1 EGO54730.1 - 0.074 13.7 0.7 0.074 13.7 0.7 1.6 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats CNDH2_C PF16858.5 EGO54730.1 - 0.56 10.0 9.5 0.34 10.7 1.1 2.5 2 1 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term FAM176 PF14851.6 EGO54730.1 - 1.9 8.1 23.0 1.6 8.4 4.8 3.3 3 0 0 3 3 3 0 FAM176 family DUF1677 PF07911.13 EGO54730.1 - 2.1 8.8 4.2 0.6 10.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1677) FAM76 PF16046.5 EGO54730.1 - 3 7.1 7.6 0.14 11.5 1.0 1.9 2 0 0 2 2 2 0 FAM76 protein SPX PF03105.19 EGO54730.1 - 3.1 7.6 16.8 5.2 6.9 16.8 1.3 1 0 0 1 1 1 0 SPX domain Med7 PF05983.11 EGO54731.1 - 1.6e-52 178.4 0.1 1.8e-52 178.2 0.1 1.0 1 0 0 1 1 1 1 MED7 protein ParE-like_toxin PF15781.5 EGO54731.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system SPOC PF07744.13 EGO54732.1 - 6.3e-29 100.8 0.0 1.1e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 EGO54732.1 - 2.8e-19 69.7 0.1 6.3e-19 68.5 0.1 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 EGO54732.1 - 1.2e-09 37.9 7.7 2.7e-09 36.8 7.7 1.6 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 EGO54732.1 - 0.15 12.2 1.9 0.33 11.0 1.9 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_2 PF13831.6 EGO54732.1 - 0.3 10.7 2.6 0.61 9.7 2.6 1.5 1 0 0 1 1 1 0 PHD-finger Proteasome PF00227.26 EGO54733.1 - 7.2e-61 205.0 0.1 8.9e-61 204.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGO54733.1 - 2.6e-13 49.4 0.1 8.7e-13 47.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 EGO54733.1 - 0.013 15.6 0.4 0.04 14.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 EGO54733.1 - 0.024 14.2 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit PAP2 PF01569.21 EGO54734.1 - 8.3e-29 100.1 0.3 8.3e-29 100.1 0.3 1.6 2 0 0 2 2 2 1 PAP2 superfamily WD40 PF00400.32 EGO54736.1 - 6.2e-41 137.6 17.9 1.8e-05 25.4 0.9 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EGO54736.1 - 1e-13 50.9 0.2 2.2e-13 49.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO54736.1 - 4.4e-12 45.5 0.6 1.2e-11 44.1 0.1 2.0 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 EGO54736.1 - 4.8e-07 30.0 1.5 0.65 10.3 0.0 5.3 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO54736.1 - 0.001 17.8 6.0 3.7 6.1 0.0 5.1 2 2 2 5 5 5 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EGO54736.1 - 0.0016 18.1 0.6 0.078 12.5 0.4 2.7 1 1 1 2 2 2 2 PQQ-like domain F-box_4 PF15966.5 EGO54736.1 - 0.0071 16.2 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 F-box HORMA PF02301.18 EGO54738.1 - 1.6e-06 27.8 0.0 1.6e-06 27.8 0.0 2.4 2 1 1 3 3 3 1 HORMA domain PRIMA1 PF16101.5 EGO54738.1 - 0.029 14.4 1.3 0.029 14.4 1.3 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DASH_Ask1 PF08655.10 EGO54738.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Ask1 NTP_transferase PF00483.23 EGO54739.1 - 2e-30 106.2 0.0 2.6e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EGO54739.1 - 1.3e-11 43.7 3.9 6.4e-06 25.7 0.0 3.5 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EGO54739.1 - 3e-06 27.7 0.0 4.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EGO54739.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Dynamin_N PF00350.23 EGO54740.1 - 1.4e-22 80.5 0.0 2.6e-21 76.4 0.0 2.7 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 EGO54740.1 - 1.7e-15 57.0 1.6 4.2e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EGO54740.1 - 0.002 18.2 0.0 0.036 14.2 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 EGO54740.1 - 0.0028 17.8 0.3 0.017 15.3 0.0 2.5 2 1 0 2 2 2 1 Dynamin GTPase effector domain YtxC PF08812.11 EGO54740.1 - 0.019 14.6 1.3 0.037 13.6 1.3 1.4 1 0 0 1 1 1 0 YtxC-like family ABC_tran PF00005.27 EGO54740.1 - 0.022 15.3 0.1 0.13 12.8 0.0 2.3 3 0 0 3 3 3 0 ABC transporter Roc PF08477.13 EGO54740.1 - 0.023 14.9 0.3 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 EGO54740.1 - 0.037 13.9 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGO54740.1 - 0.039 13.7 0.1 0.088 12.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Vps35 PF03635.17 EGO54740.1 - 0.045 12.3 0.6 0.069 11.6 0.6 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 AAA_15 PF13175.6 EGO54740.1 - 0.055 13.2 0.7 0.78 9.4 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_16 PF13191.6 EGO54740.1 - 0.086 13.2 0.1 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF3744 PF12558.8 EGO54740.1 - 0.15 12.9 0.0 0.56 11.0 0.0 2.0 1 0 0 1 1 1 0 ATP-binding cassette cobalt transporter PduV-EutP PF10662.9 EGO54740.1 - 0.18 11.6 0.0 18 5.0 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation WSC PF01822.19 EGO54741.1 - 1.1e-70 233.9 45.5 7.3e-21 74.2 3.9 4.3 4 0 0 4 4 4 4 WSC domain PY_rept_46 PF09689.10 EGO54741.1 - 0.13 12.8 0.3 0.28 11.8 0.3 1.5 1 0 0 1 1 1 0 Plasmodium yoelii repeat (PY_rept_46) Amino_oxidase PF01593.24 EGO54743.1 - 1.7e-20 73.8 0.0 9.7e-12 44.9 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EGO54743.1 - 5.9e-09 35.5 0.4 9.7e-09 34.8 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGO54743.1 - 9.9e-09 35.3 0.9 4.3e-08 33.3 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGO54743.1 - 2.5e-07 30.2 0.1 4.3e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EGO54743.1 - 1.4e-05 24.8 0.0 3.8e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGO54743.1 - 1.5e-05 24.6 1.3 2.8e-05 23.7 1.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO54743.1 - 5.2e-05 22.6 0.0 8.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO54743.1 - 5.9e-05 22.5 0.0 0.00014 21.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGO54743.1 - 9.8e-05 21.8 0.2 0.00015 21.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EGO54743.1 - 0.00063 18.6 0.4 0.00095 18.0 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 EGO54743.1 - 0.0023 17.1 0.2 0.0034 16.5 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EGO54743.1 - 0.0074 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 EGO54743.1 - 0.011 16.3 0.1 0.021 15.3 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Beta-lactamase PF00144.24 EGO54745.1 - 4.3e-34 118.2 0.0 1.5e-28 100.0 0.0 2.6 2 1 0 2 2 2 2 Beta-lactamase MMR_HSR1 PF01926.23 EGO54746.1 - 2.8e-06 27.4 0.0 4.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGO54746.1 - 7.7e-06 25.4 0.0 2e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 EGO54746.1 - 0.0024 17.8 0.5 0.0057 16.6 0.5 1.6 1 0 0 1 1 1 1 RsgA GTPase DUF3040 PF11239.8 EGO54746.1 - 0.0066 16.7 0.3 0.024 14.9 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3040) FeoB_N PF02421.18 EGO54746.1 - 0.016 14.7 0.1 0.025 14.1 0.1 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_33 PF13671.6 EGO54746.1 - 0.02 15.0 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EGO54746.1 - 0.065 13.3 0.7 0.065 13.3 0.7 1.9 2 1 0 2 2 2 0 Helicase HerA, central domain CEP63 PF17045.5 EGO54746.1 - 0.076 12.9 6.3 0.75 9.7 1.2 2.3 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa Exonuc_VII_L PF02601.15 EGO54746.1 - 0.15 11.6 1.1 0.22 11.1 1.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dynamin_N PF00350.23 EGO54746.1 - 0.27 11.3 5.2 5.1 7.1 0.7 2.8 2 2 1 3 3 3 0 Dynamin family DUF4349 PF14257.6 EGO54746.1 - 0.94 8.9 2.9 1.3 8.4 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) Spc7 PF08317.11 EGO54746.1 - 0.99 8.2 4.4 1.5 7.6 4.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_23 PF13476.6 EGO54747.1 - 0.0064 17.0 10.5 2.1 8.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain UT PF03253.14 EGO54747.1 - 0.0084 15.3 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 Urea transporter NB-ARC PF00931.22 EGO54747.1 - 0.014 14.6 3.5 0.13 11.4 0.1 2.5 2 1 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 EGO54747.1 - 0.02 14.6 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 EGO54747.1 - 0.045 13.8 3.5 0.39 10.8 0.2 2.3 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 EGO54747.1 - 0.076 13.1 9.4 0.14 12.3 0.6 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain TraF_2 PF13729.6 EGO54747.1 - 0.11 11.9 0.2 0.18 11.2 0.2 1.2 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein MMR_HSR1 PF01926.23 EGO54747.1 - 0.21 11.7 2.0 1 9.4 2.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Stathmin PF00836.19 EGO54747.1 - 0.58 10.1 11.0 0.85 9.6 10.3 1.6 1 1 0 1 1 1 0 Stathmin family DUF1451 PF07295.11 EGO54747.1 - 0.61 10.1 6.1 1 9.4 6.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain AAA_16 PF13191.6 EGO54747.1 - 1.5 9.2 3.7 3.2 8.1 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain OmpH PF03938.14 EGO54747.1 - 1.6 9.1 12.0 2.9 8.2 12.0 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_33 PF13671.6 EGO54747.1 - 1.7 8.8 4.1 1.4 9.0 0.3 2.3 2 1 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.15 EGO54747.1 - 2.1 7.9 5.3 2.9 7.4 5.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 EGO54747.1 - 4.2 7.1 7.1 0.69 9.6 1.4 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EGO54747.1 - 4.7 7.7 9.6 80 3.7 9.6 2.5 1 1 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 EGO54748.1 - 6e-49 166.2 0.1 9.8e-49 165.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EGO54748.1 - 7.2e-42 141.9 5.2 1.2e-41 141.2 5.2 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EGO54748.1 - 8.1e-18 64.2 0.0 1.5e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGO54748.1 - 1.5e-06 28.5 0.0 3.5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGO54748.1 - 3.5e-05 23.9 0.0 9e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 EGO54748.1 - 0.0001 22.3 0.0 0.00066 19.7 0.0 2.3 2 1 0 2 2 2 1 Elongation Factor G, domain II Ras PF00071.22 EGO54748.1 - 0.00016 21.3 0.0 0.00049 19.7 0.0 1.8 2 0 0 2 2 2 1 Ras family SRPRB PF09439.10 EGO54748.1 - 0.0068 15.9 0.2 0.02 14.3 0.0 1.9 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit RF3_C PF16658.5 EGO54748.1 - 0.12 12.2 0.0 0.37 10.6 0.0 1.8 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain Roc PF08477.13 EGO54748.1 - 0.12 12.6 0.0 0.67 10.2 0.0 2.3 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MIT PF04212.18 EGO54749.1 - 8.5e-14 51.4 1.1 1.6e-13 50.5 1.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Methyltransf_23 PF13489.6 EGO54750.1 - 2.7e-20 72.8 0.0 6.4e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO54750.1 - 9.9e-11 42.2 0.0 2.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO54750.1 - 5.9e-09 35.9 0.0 3.4e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO54750.1 - 1.1e-07 32.4 0.0 2.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO54750.1 - 1.6e-06 28.8 0.0 6.9e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGO54750.1 - 0.0055 16.1 0.0 0.0095 15.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 EGO54750.1 - 0.029 14.1 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase MTS PF05175.14 EGO54750.1 - 0.057 13.0 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_4 PF02390.17 EGO54750.1 - 0.057 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Glyco_hydro_10 PF00331.20 EGO54751.1 - 1.6e-101 339.6 0.9 1.8e-101 339.4 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 YDG PF18657.1 EGO54751.1 - 1.2 9.3 4.7 11 6.3 3.8 2.4 1 1 1 2 2 2 0 YDG domain CDH-cyt PF16010.5 EGO54752.1 - 2.6e-58 196.7 0.2 2e-57 193.8 0.1 2.2 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 EGO54752.1 - 1.9e-26 93.1 0.0 3.6e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO54752.1 - 4.4e-22 79.2 0.1 8.6e-22 78.2 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGO54752.1 - 2.6e-09 36.7 0.1 0.00072 18.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EGO54752.1 - 0.00013 22.1 0.0 0.00038 20.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO54752.1 - 0.00029 20.5 0.1 0.018 14.6 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase DOMON PF03351.17 EGO54752.1 - 0.0011 19.2 0.1 0.0029 17.8 0.1 1.6 1 0 0 1 1 1 1 DOMON domain Pyr_redox_2 PF07992.14 EGO54752.1 - 0.0032 16.8 0.0 0.0057 15.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO54752.1 - 0.0033 16.2 0.1 0.0051 15.6 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EGO54752.1 - 0.0084 15.4 1.0 0.012 14.8 0.4 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGO54752.1 - 0.02 14.2 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EGO54752.1 - 0.028 13.5 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EGO54752.1 - 0.057 14.0 0.0 1.3 9.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO54752.1 - 0.064 12.6 0.0 0.55 9.5 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HCV_NS1 PF01560.17 EGO54752.1 - 0.27 9.9 3.5 14 4.2 3.2 2.1 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein E2/NS1 Arrestin_N PF00339.29 EGO54753.1 - 0.011 15.9 0.5 0.028 14.5 0.5 1.8 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain BTB PF00651.31 EGO54754.1 - 6.8e-08 32.7 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EGO54755.1 - 0.029 14.6 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain HET PF06985.11 EGO54756.1 - 1.9e-07 31.5 5.9 1e-06 29.2 2.5 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 EGO54757.1 - 3.7e-18 65.9 0.3 5.7e-06 26.8 0.0 5.9 5 1 0 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 EGO54757.1 - 1.8e-16 59.7 5.2 8.5e-05 22.8 0.0 6.9 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 EGO54757.1 - 4.8e-14 52.5 4.0 2.7e-05 24.6 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO54757.1 - 5.4e-14 52.1 1.3 0.00017 21.8 0.0 5.9 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO54757.1 - 6.9e-11 41.4 8.5 1.4 9.7 0.0 8.6 10 0 0 10 10 10 3 Ankyrin repeat But2 PF09792.9 EGO54758.1 - 0.0046 17.4 0.2 0.014 15.8 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain CAP59_mtransfer PF11735.8 EGO54759.1 - 2.3e-68 230.5 0.0 3.1e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF3439 PF11921.8 EGO54759.1 - 0.047 13.7 1.6 0.083 12.9 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TrbL PF04610.14 EGO54760.1 - 0.0095 15.7 1.1 0.014 15.2 1.1 1.1 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein Glycophorin_A PF01102.18 EGO54760.1 - 0.061 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Glycophorin A DUF4328 PF14219.6 EGO54760.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) PAP1 PF08601.10 EGO54760.1 - 0.4 10.4 3.8 0.62 9.7 3.8 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 FYVE PF01363.21 EGO54763.1 - 0.11 12.6 2.4 0.22 11.7 2.4 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-C2H2 PF00096.26 EGO54764.1 - 3.5e-06 27.2 12.1 0.0071 16.8 0.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO54764.1 - 3.6e-05 24.0 7.6 0.0042 17.4 0.8 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_8 PF15909.5 EGO54764.1 - 3.8e-05 23.9 4.7 0.0087 16.3 0.8 2.4 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 EGO54764.1 - 0.0053 17.5 12.7 0.53 11.3 1.3 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf_Hakai PF18408.1 EGO54764.1 - 1.3 8.8 6.1 0.75 9.6 0.1 2.5 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain FOXP-CC PF16159.5 EGO54764.1 - 2.2 9.0 6.5 18 6.1 0.4 2.6 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 EGO54764.1 - 4.3 7.4 14.2 3.9 7.6 0.8 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Aspzincin_M35 PF14521.6 EGO54765.1 - 1.2e-35 123.2 4.0 2.7e-35 122.0 4.0 1.6 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 EGO54765.1 - 2.9e-30 105.3 14.3 3.6e-30 105.0 14.3 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family DUF4232 PF14016.6 EGO54765.1 - 0.0007 19.7 1.1 0.0023 18.1 1.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4232) HRXXH PF13933.6 EGO54765.1 - 0.036 13.6 0.4 0.036 13.6 0.4 1.7 2 0 0 2 2 2 0 Putative peptidase family DUF4352 PF11611.8 EGO54765.1 - 0.072 13.4 0.0 0.43 10.9 0.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4352) Cutinase PF01083.22 EGO54767.1 - 5e-58 196.0 7.4 6.5e-58 195.6 7.4 1.1 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.18 EGO54767.1 - 2e-11 43.7 20.3 2e-11 43.7 20.3 4.4 5 2 0 5 5 5 1 Fungal cellulose binding domain PE-PPE PF08237.11 EGO54767.1 - 5.3e-06 26.1 0.2 7.1e-06 25.7 0.2 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 EGO54767.1 - 0.0032 17.1 0.1 0.0046 16.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO54767.1 - 0.0097 15.2 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGO54767.1 - 0.019 15.6 0.1 0.024 15.3 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIP PF03583.14 EGO54767.1 - 0.11 11.8 0.2 0.17 11.2 0.2 1.2 1 0 0 1 1 1 0 Secretory lipase Cation_efflux PF01545.21 EGO54769.1 - 1.5e-18 67.2 0.9 2.1e-18 66.8 0.9 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGO54769.1 - 0.0001 22.4 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Beta_propel PF09826.9 EGO54770.1 - 0.032 13.1 0.0 1.5 7.5 0.0 2.2 1 1 2 3 3 3 0 Beta propeller domain Cation_ATPase_C PF00689.21 EGO54772.1 - 6.7e-50 169.3 1.9 6.7e-50 169.3 1.9 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGO54772.1 - 1.9e-35 122.0 0.4 1.9e-35 122.0 0.4 3.1 4 1 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGO54772.1 - 2e-23 82.3 0.0 4.1e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGO54772.1 - 6.5e-18 65.8 0.9 1.9e-17 64.3 0.9 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGO54772.1 - 1.3e-09 37.6 0.2 9.4e-08 31.6 0.0 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGO54772.1 - 8.2e-07 29.0 0.4 4.6e-05 23.3 0.5 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 EGO54772.1 - 0.0028 16.5 0.5 0.0087 14.9 0.3 1.8 2 0 0 2 2 2 1 Lipopolysaccharide export system permease LptF/LptG TctB PF07331.11 EGO54772.1 - 1.2 9.4 5.9 3.9 7.8 0.4 2.9 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family Hexapep PF00132.24 EGO54773.1 - 3.3e-15 55.1 15.5 1.3e-10 40.6 7.9 2.7 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGO54773.1 - 9.4e-13 47.7 13.9 4.4e-09 35.9 7.4 2.6 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 EGO54773.1 - 0.014 15.6 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Maltose acetyltransferase IncD PF17628.2 EGO54773.1 - 0.082 12.7 1.2 0.2 11.4 1.2 1.6 1 0 0 1 1 1 0 Inclusion membrane protein D Macoilin PF09726.9 EGO54773.1 - 5.2 5.5 8.6 7.1 5.0 8.6 1.1 1 0 0 1 1 1 0 Macoilin family XFP_N PF09364.10 EGO54775.1 - 5.4e-151 502.5 0.0 7.1e-151 502.1 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 EGO54775.1 - 7.3e-77 257.4 0.0 1.4e-76 256.5 0.0 1.5 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 EGO54775.1 - 1.1e-75 253.2 0.0 2.1e-75 252.3 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 EGO54775.1 - 0.0091 15.8 0.1 0.024 14.4 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain AflR PF08493.10 EGO54776.1 - 0.15 11.5 2.3 0.25 10.8 2.4 1.4 1 1 0 1 1 1 0 Aflatoxin regulatory protein ABC2_membrane_2 PF12679.7 EGO54777.1 - 2.2 7.5 5.8 3.6 6.8 5.7 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Pkinase PF00069.25 EGO54780.1 - 4.7e-07 29.4 0.0 5.8e-05 22.6 0.0 3.3 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO54780.1 - 6.5e-05 22.3 0.0 1.1 8.5 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Afi1 PF07792.12 EGO54780.1 - 0.99 9.9 6.1 0.49 10.9 2.6 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ank_4 PF13637.6 EGO54781.1 - 2.1e-20 72.8 0.0 1.6e-08 34.9 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO54781.1 - 1.9e-16 60.4 0.0 6.2e-16 58.8 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGO54781.1 - 3.5e-14 52.5 0.2 0.00042 20.6 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EGO54781.1 - 7.5e-13 47.4 0.0 0.016 15.7 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EGO54781.1 - 8.1e-12 45.1 0.0 1.2e-05 25.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) FAR1 PF03101.15 EGO54781.1 - 6.8e-08 33.1 0.5 6.8e-08 33.1 0.5 2.6 3 0 0 3 3 3 1 FAR1 DNA-binding domain Ferritin_2 PF13668.6 EGO54782.1 - 5.4e-16 59.0 0.1 8e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain SR-25 PF10500.9 EGO54783.1 - 0.0039 16.8 5.0 0.0039 16.8 5.0 3.4 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein DDHD PF02862.17 EGO54783.1 - 7 6.7 13.3 9.1 6.4 4.9 2.3 2 0 0 2 2 2 0 DDHD domain Ank_4 PF13637.6 EGO54785.1 - 0.00093 19.7 0.1 0.66 10.6 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO54785.1 - 0.0027 18.3 0.0 0.032 14.8 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) AAT PF03417.16 EGO54785.1 - 0.0096 15.6 0.0 2.7 7.6 0.3 2.4 2 0 0 2 2 2 2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NPV_P10 PF05531.12 EGO54785.1 - 0.023 15.2 1.5 0.023 15.2 1.5 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_p24 PF05073.12 EGO54785.1 - 0.28 11.0 3.8 1.3 8.8 0.6 2.6 1 1 1 2 2 2 0 Baculovirus P24 capsid protein TPR_MLP1_2 PF07926.12 EGO54785.1 - 0.6 10.2 8.8 0.21 11.7 2.1 3.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Glyco_transf_25 PF01755.17 EGO54786.1 - 6.4e-08 32.7 0.0 1e-07 32.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) HTH_Tnp_IS1 PF12759.7 EGO54787.1 - 0.33 10.6 1.1 7.9 6.2 0.2 2.6 2 0 0 2 2 2 0 InsA C-terminal domain Glyco_hydro_114 PF03537.13 EGO54788.1 - 8.2e-81 270.7 0.1 1.1e-80 270.3 0.1 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 ETRAMP PF09716.10 EGO54788.1 - 0.024 14.7 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Spherulin4 PF12138.8 EGO54789.1 - 3.2e-75 252.9 0.0 4.4e-67 226.2 0.0 3.0 1 1 1 3 3 3 3 Spherulation-specific family 4 Epimerase PF01370.21 EGO54791.1 - 2.3e-39 135.3 0.1 1e-38 133.2 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO54791.1 - 4e-32 111.9 0.0 3.6e-29 102.2 0.0 2.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGO54791.1 - 9.4e-09 34.7 0.1 8.9e-07 28.2 0.1 2.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGO54791.1 - 2.5e-06 26.8 0.0 1.5e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EGO54791.1 - 7.3e-06 25.3 0.3 0.00017 20.9 0.3 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EGO54791.1 - 0.00011 22.1 0.0 0.093 12.6 0.0 2.3 2 0 0 2 2 2 2 KR domain DUF2709 PF10915.8 EGO54791.1 - 0.002 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2709) UDPG_MGDP_dh_N PF03721.14 EGO54791.1 - 0.0038 16.8 0.1 0.0084 15.7 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.25 EGO54791.1 - 0.006 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Pyr_redox_2 PF07992.14 EGO54791.1 - 0.011 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pribosyltran PF00156.27 EGO54791.1 - 0.013 15.0 0.0 0.72 9.4 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosyl transferase domain TrkA_N PF02254.18 EGO54791.1 - 0.082 13.2 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 EGO54791.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glycos_transf_1 PF00534.20 EGO54792.1 - 1.8e-14 53.7 0.0 4.1e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGO54792.1 - 4.8e-14 52.9 0.1 9.7e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 EGO54792.1 - 2.1e-05 24.4 0.0 5.4e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) Chorismate_bind PF00425.18 EGO54794.1 - 1.4e-83 280.4 0.0 1.1e-67 228.3 0.0 3.0 3 0 0 3 3 3 2 chorismate binding enzyme Anth_synt_I_N PF04715.13 EGO54794.1 - 1.1e-29 103.5 0.0 2.4e-26 92.6 0.0 3.0 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region POR PF01558.18 EGO54794.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase DUF4690 PF15756.5 EGO54795.1 - 0.075 13.6 0.1 0.12 13.0 0.1 1.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Insulin_TMD PF17870.1 EGO54795.1 - 0.14 12.2 0.2 0.24 11.5 0.2 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment p450 PF00067.22 EGO54796.1 - 7.6e-23 81.0 0.0 9.5e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Dynamin_N PF00350.23 EGO54796.1 - 0.1 12.7 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Dynamin family Dala_Dala_lig_C PF07478.13 EGO54797.1 - 4.3e-44 150.5 0.0 5.3e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 EGO54797.1 - 2.5e-21 76.1 0.0 8.6e-21 74.3 0.0 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase N-terminus CPSase_L_D2 PF02786.17 EGO54797.1 - 2.3e-09 37.1 0.0 5.7e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 EGO54797.1 - 5.2e-08 32.6 0.2 1.3e-07 31.4 0.2 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EGO54797.1 - 2.8e-07 30.7 0.0 4.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 EGO54797.1 - 9.7e-06 25.3 0.0 2.6e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EGO54797.1 - 0.0018 18.0 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain UbiA PF01040.18 EGO54798.1 - 1.3e-30 106.5 6.3 1.8e-30 106.1 6.3 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family HAD_2 PF13419.6 EGO54799.1 - 3.2e-05 24.1 0.0 8.2e-05 22.8 0.0 1.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO54799.1 - 0.03 14.4 0.0 0.069 13.2 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase PF00702.26 EGO54799.1 - 0.078 13.3 0.0 0.29 11.4 0.0 1.8 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Glyco_transf_90 PF05686.12 EGO54801.1 - 0.00037 19.5 1.2 0.0061 15.5 0.2 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 90 DUF3511 PF12023.8 EGO54801.1 - 3.1 7.7 4.3 6.2 6.7 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) Glyco_hydro_45 PF02015.16 EGO54803.1 - 6.3e-86 287.6 17.2 1e-85 287.0 17.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 CBM_1 PF00734.18 EGO54803.1 - 2.3e-11 43.4 13.0 2.3e-11 43.4 13.0 3.8 3 0 0 3 3 3 1 Fungal cellulose binding domain Big_1 PF02369.16 EGO54803.1 - 0.22 11.5 0.1 0.22 11.5 0.1 2.4 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) RNA_pol_Rpb2_6 PF00562.28 EGO54804.1 - 1.8e-125 419.0 0.1 2.8e-125 418.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGO54804.1 - 5.8e-51 172.9 0.0 2.8e-50 170.6 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EGO54804.1 - 7.4e-45 152.9 0.0 1.4e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EGO54804.1 - 1.2e-33 115.4 0.1 3.6e-33 113.8 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EGO54804.1 - 3.4e-25 88.0 0.1 8.8e-25 86.7 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EGO54804.1 - 5.2e-24 84.6 0.4 1.5e-23 83.1 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 EGO54804.1 - 5.7e-23 81.0 0.9 1.4e-22 79.7 0.5 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_45 PF10385.9 EGO54804.1 - 0.063 13.5 0.2 2.1 8.7 0.0 2.7 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain PET117 PF15786.5 EGO54806.1 - 5e-26 90.7 1.8 5.9e-26 90.5 1.8 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial RNA_pol_Rpb1_6 PF04992.14 EGO54806.1 - 0.011 15.6 1.1 0.013 15.4 1.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 COX16 PF14138.6 EGO54806.1 - 0.023 15.2 0.1 0.028 14.9 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 V-ATPase_G PF03179.15 EGO54807.1 - 1.3e-33 115.6 17.5 1.5e-33 115.5 17.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit YusW PF14039.6 EGO54807.1 - 0.003 18.0 2.6 0.0051 17.3 2.6 1.4 1 0 0 1 1 1 1 YusW-like protein ATP-synt_B PF00430.18 EGO54807.1 - 0.12 12.5 26.5 0.046 13.8 11.9 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) FdhE PF04216.12 EGO54807.1 - 0.16 11.8 4.6 0.18 11.7 4.6 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Microvir_H PF04687.12 EGO54807.1 - 0.18 11.2 4.3 0.22 10.9 4.3 1.0 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) OmpH PF03938.14 EGO54807.1 - 0.21 11.9 13.7 0.26 11.6 13.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Asp-B-Hydro_N PF05279.11 EGO54807.1 - 0.38 10.8 10.9 0.43 10.6 10.9 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region V-ATPase_G_2 PF16999.5 EGO54807.1 - 0.44 11.0 22.3 0.84 10.1 22.2 1.5 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Borrelia_P83 PF05262.11 EGO54807.1 - 0.48 8.9 13.4 0.53 8.7 13.4 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein ATP11 PF06644.11 EGO54807.1 - 0.5 10.1 9.7 0.63 9.8 9.7 1.0 1 0 0 1 1 1 0 ATP11 protein DUF3552 PF12072.8 EGO54807.1 - 2.2 7.7 24.2 29 4.0 24.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF3987 PF13148.6 EGO54807.1 - 2.6 7.0 11.1 3.3 6.6 11.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Atg14 PF10186.9 EGO54807.1 - 3.4 6.7 8.8 4.3 6.3 8.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 vATP-synt_E PF01991.18 EGO54807.1 - 3.7 6.9 18.9 8.4 5.7 18.9 1.5 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit CemA PF03040.14 EGO54807.1 - 7.2 6.5 5.6 8.8 6.2 5.6 1.1 1 0 0 1 1 1 0 CemA family DUF4407 PF14362.6 EGO54807.1 - 9.8 5.4 11.5 11 5.2 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CTNNBL PF08216.11 EGO54808.1 - 4e-38 129.8 1.1 7.9e-38 128.8 0.1 2.0 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm_3 PF16186.5 EGO54808.1 - 0.0016 17.9 0.2 0.85 9.2 0.0 3.3 3 0 0 3 3 3 2 Atypical Arm repeat Mo25 PF08569.11 EGO54808.1 - 0.0039 16.6 0.1 0.0072 15.7 0.1 1.5 1 0 0 1 1 1 1 Mo25-like Arm PF00514.23 EGO54808.1 - 0.026 14.6 0.0 2.4 8.3 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF5578 PF17741.1 EGO54808.1 - 0.096 12.1 0.9 4 6.8 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5578) RIH_assoc PF08454.11 EGO54808.1 - 0.15 12.0 0.0 4.3 7.2 0.0 2.6 2 1 0 2 2 2 0 RyR and IP3R Homology associated Orthopox_F14 PF06076.12 EGO54808.1 - 7.8 6.8 8.4 1.8 8.9 3.5 2.6 2 1 0 2 2 2 0 Orthopoxvirus F14 protein His_Phos_1 PF00300.22 EGO54809.1 - 0.0003 20.6 0.0 0.00041 20.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) T2SSI PF02501.17 EGO54809.1 - 0.034 14.3 0.2 0.052 13.7 0.2 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I HET PF06985.11 EGO54810.1 - 8.8e-27 94.3 0.0 2.1e-26 93.0 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BAR_2 PF10455.9 EGO54812.1 - 0.002 17.4 0.1 0.0072 15.5 0.1 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Peptidase_S51 PF03575.17 EGO54812.1 - 0.12 12.0 0.3 0.29 10.7 0.1 1.6 2 0 0 2 2 2 0 Peptidase family S51 Cu-oxidase_2 PF07731.14 EGO54813.1 - 1.9e-42 144.2 9.7 4.1e-40 136.7 0.9 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGO54813.1 - 1.2e-39 135.0 1.8 1.2e-39 135.0 1.8 3.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 EGO54813.1 - 4.7e-38 130.8 0.0 1.4e-37 129.3 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase DUF1996 PF09362.10 EGO54816.1 - 3.3e-05 24.0 0.0 3.5e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RNase_H PF00075.24 EGO54818.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 RNase H Mvb12 PF09452.10 EGO54818.1 - 0.25 11.8 3.2 1.1 9.7 1.8 2.2 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 DUF4764 PF15961.5 EGO54819.1 - 0.0025 16.6 2.1 0.003 16.4 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4764) DUF4050 PF13259.6 EGO54819.1 - 0.0082 16.5 5.5 0.011 16.0 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) Pectate_lyase_3 PF12708.7 EGO54821.1 - 3.3e-37 128.4 4.2 2.7e-30 105.9 1.5 2.3 2 0 0 2 2 2 2 Pectate lyase superfamily protein NosD PF05048.13 EGO54821.1 - 0.099 11.9 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Glyco_hydro_7 PF00840.20 EGO54822.1 - 1.5e-184 613.8 16.0 1.7e-184 613.6 16.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF3764 PF12594.8 EGO54822.1 - 0.082 13.0 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) Toxin_11 PF07473.11 EGO54822.1 - 0.75 9.9 6.4 2.9 8.1 6.4 2.0 1 0 0 1 1 1 0 Spasmodic peptide gm9a; conotoxin from Conus species RNase_H PF00075.24 EGO54824.1 - 0.0048 17.1 0.0 0.16 12.1 0.0 2.7 1 1 0 1 1 1 1 RNase H Pex14_N PF04695.13 EGO54824.1 - 1.7 9.3 8.8 2.7 8.6 8.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ECF-ribofla_trS PF07155.12 EGO54825.1 - 3.5 7.6 9.7 0.49 10.4 2.2 2.3 2 0 0 2 2 2 0 ECF-type riboflavin transporter, S component Fib_alpha PF08702.10 EGO54826.1 - 0.0002 21.6 3.3 0.0053 16.9 0.0 2.1 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family CorA PF01544.18 EGO54826.1 - 0.002 17.5 0.0 0.0052 16.1 0.0 1.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein PSDC PF12588.8 EGO54828.1 - 7.2e-43 145.9 0.0 1.1e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EGO54828.1 - 2.2e-39 135.1 0.0 3e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.6 EGO54828.1 - 0.0016 18.4 0.0 0.94 9.5 0.0 2.4 2 0 0 2 2 2 2 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 EGO54828.1 - 0.067 13.0 0.4 2.7 7.9 0.2 2.4 2 0 0 2 2 2 0 Biotin-requiring enzyme Peptidase_M23 PF01551.22 EGO54828.1 - 0.069 13.4 0.1 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M23 RNase_H PF00075.24 EGO54830.1 - 7.4e-08 32.7 0.0 2.4e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 RNase H Dicistro_VP4 PF11492.8 EGO54830.1 - 0.41 10.6 2.5 1 9.4 2.5 1.7 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 tRNA-synt_2d PF01409.20 EGO54832.1 - 1.1e-84 283.8 0.0 1.8e-84 283.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EGO54832.1 - 1.1e-17 64.1 1.9 2.9e-17 62.7 1.9 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EGO54832.1 - 2.7e-07 30.2 0.0 0.049 13.1 0.0 3.2 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 EGO54832.1 - 8e-05 22.5 2.8 0.00012 22.0 0.6 2.5 2 0 0 2 2 2 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 EGO54832.1 - 8.3e-05 21.8 0.2 0.0034 16.5 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EGO54832.1 - 0.0023 17.9 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) GTF2I PF02946.14 EGO54832.1 - 0.11 12.6 0.0 3 8.0 0.1 2.6 2 0 0 2 2 2 0 GTF2I-like repeat adh_short_C2 PF13561.6 EGO54833.1 - 2.3e-33 115.7 0.4 1.4e-18 67.3 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO54833.1 - 5.6e-31 107.5 6.4 1.8e-19 70.0 0.6 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EGO54833.1 - 7.7e-12 45.5 0.6 2.3e-11 43.9 0.3 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EGO54833.1 - 0.0015 17.7 0.2 0.003 16.7 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Glu_dehyd_C PF16912.5 EGO54833.1 - 0.036 13.5 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Cys_Met_Meta_PP PF01053.20 EGO54834.1 - 1.6e-23 82.8 0.0 2.3e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TMEM214 PF10151.9 EGO54835.1 - 0.022 13.2 3.8 0.024 13.1 3.8 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator RSRP PF17069.5 EGO54835.1 - 0.13 11.8 8.2 0.16 11.5 8.2 1.0 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CCDC24 PF15669.5 EGO54835.1 - 0.22 11.4 2.2 0.24 11.3 2.2 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family NPR3 PF03666.13 EGO54835.1 - 3.9 6.2 9.9 4.2 6.1 9.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RNase_H PF00075.24 EGO54836.1 - 2.6e-07 30.9 0.0 4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 RNase H MFS_1 PF07690.16 EGO54837.1 - 2.9e-23 82.4 80.2 5.2e-20 71.7 52.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 EGO54837.1 - 0.61 9.9 6.0 2.2 8.0 4.4 2.7 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Serglycin PF04360.12 EGO54839.1 - 0.021 14.8 8.5 0.021 14.8 8.5 1.4 1 1 0 1 1 1 0 Serglycin Pacs-1 PF10254.9 EGO54840.1 - 1.2 8.1 5.4 1.2 8.1 5.4 1.0 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Period_C PF12114.8 EGO54840.1 - 5 6.7 20.0 5.2 6.6 20.0 1.0 1 0 0 1 1 1 0 Period protein 2/3C-terminal region CDC45 PF02724.14 EGO54841.1 - 2.6 6.2 31.4 0.16 10.2 14.0 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF2379 PF09543.10 EGO54845.1 - 0.24 11.6 0.0 0.37 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) Ribosomal_60s PF00428.19 EGO54847.1 - 0.14 12.8 12.1 0.62 10.7 0.3 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein PTR2 PF00854.21 EGO54848.1 - 1.1e-42 146.3 0.3 1.6e-42 145.7 0.3 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EGO54848.1 - 8.7e-10 38.0 16.9 8.7e-10 38.0 16.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1269 PF06897.12 EGO54848.1 - 0.037 14.3 0.1 1.9 8.8 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) ABC2_membrane_3 PF12698.7 EGO54848.1 - 0.34 10.0 14.7 0.3 10.1 0.8 3.5 3 1 1 4 4 4 0 ABC-2 family transporter protein PCMT PF01135.19 EGO54849.1 - 6.7e-55 186.1 0.0 9e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGO54849.1 - 3.6e-05 23.6 0.0 5.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGO54849.1 - 0.0002 21.4 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO54849.1 - 0.00032 21.3 0.0 0.00051 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO54849.1 - 0.0018 18.1 0.0 0.0025 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO54849.1 - 0.0072 17.0 0.0 0.011 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EGO54849.1 - 0.027 15.5 0.0 0.046 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EGO54849.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 EGO54849.1 - 0.27 10.3 0.0 0.37 9.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF2370 PF10176.9 EGO54850.1 - 3.9e-89 298.2 0.0 7.8e-89 297.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Cwf_Cwc_15 PF04889.12 EGO54850.1 - 0.86 9.3 5.5 1.5 8.5 5.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3246 PF11596.8 EGO54850.1 - 8.4 5.7 19.4 41 3.5 19.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3246) Mito_carr PF00153.27 EGO54851.1 - 1.9e-43 146.3 9.0 2.8e-21 75.2 0.2 4.2 4 1 0 4 4 4 4 Mitochondrial carrier protein Collagen PF01391.18 EGO54854.1 - 0.00011 21.9 16.6 0.00015 21.5 16.6 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Period_C PF12114.8 EGO54854.1 - 0.24 11.0 1.8 0.29 10.7 1.8 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Filament_head PF04732.14 EGO54854.1 - 0.45 11.4 11.1 0.73 10.7 11.1 1.3 1 0 0 1 1 1 0 Intermediate filament head (DNA binding) region Peptidase_M35 PF02102.15 EGO54856.1 - 1.7e-87 293.6 13.8 2e-87 293.4 13.8 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EGO54856.1 - 3.3e-42 144.5 4.9 3.3e-42 144.5 4.9 1.6 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase DUF825 PF05695.12 EGO54856.1 - 0.069 10.3 0.1 0.09 9.9 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) DAO PF01266.24 EGO54858.1 - 8.9e-45 153.8 0.3 1.1e-44 153.5 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 EGO54858.1 - 9.7e-12 44.7 0.2 5.6e-11 42.2 0.2 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.6 EGO54858.1 - 4.3e-09 36.5 0.2 1.2e-08 35.0 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EGO54858.1 - 5.8e-07 29.2 2.2 1.3e-05 24.7 2.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO54858.1 - 2.1e-06 27.1 0.5 3.1e-06 26.5 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO54858.1 - 3e-06 26.7 0.0 5.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGO54858.1 - 6.1e-06 25.7 0.0 9.4e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGO54858.1 - 1.8e-05 24.1 0.0 3.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EGO54858.1 - 6.5e-05 23.4 0.7 0.00015 22.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGO54858.1 - 0.00017 20.8 0.4 0.0021 17.2 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EGO54858.1 - 0.00021 20.7 0.0 0.00045 19.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO54858.1 - 0.00028 19.7 0.1 0.0004 19.2 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 EGO54858.1 - 0.00095 18.3 0.1 0.0053 15.9 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.24 EGO54858.1 - 0.0069 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase ApbA PF02558.16 EGO54858.1 - 0.03 14.0 0.4 0.11 12.2 0.2 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 EGO54858.1 - 0.036 14.1 0.1 0.11 12.5 0.1 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 EGO54858.1 - 0.038 13.9 0.5 0.079 12.8 0.5 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 EGO54858.1 - 0.088 11.6 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 EGO54858.1 - 0.19 12.0 0.3 0.38 11.0 0.3 1.5 1 0 0 1 1 1 0 TrkA-N domain RTA1 PF04479.13 EGO54859.1 - 3.9e-61 206.3 3.0 5.1e-61 205.9 3.0 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3169 PF11368.8 EGO54859.1 - 0.013 15.1 0.3 0.013 15.1 0.3 1.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DUF962 PF06127.11 EGO54859.1 - 0.12 12.5 0.6 1.3 9.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Abhydrolase_9_N PF15420.6 EGO54859.1 - 0.22 11.5 3.7 0.18 11.8 0.9 2.0 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF4233 PF14017.6 EGO54859.1 - 0.35 11.2 14.7 5.9 7.3 0.3 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4233) DUF3098 PF11297.8 EGO54859.1 - 0.69 9.6 6.4 4.3 7.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) Zn_clus PF00172.18 EGO54860.1 - 9e-10 38.5 6.5 1.7e-09 37.7 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGO54860.1 - 0.11 11.3 2.6 0.047 12.5 0.3 1.5 2 0 0 2 2 2 0 Fungal specific transcription factor domain SPX PF03105.19 EGO54860.1 - 3.4 7.5 8.3 3.6 7.4 1.2 2.1 2 0 0 2 2 2 0 SPX domain BTB PF00651.31 EGO54861.1 - 2.2e-13 50.4 0.0 3.6e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TFIIA PF03153.13 EGO54861.1 - 0.5 10.3 12.2 0.78 9.7 12.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit COG5 PF10392.9 EGO54862.1 - 2.7e-39 134.3 0.7 1.5e-38 131.9 0.0 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF1722 PF08349.11 EGO54862.1 - 0.16 12.2 0.0 0.45 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) ATG16 PF08614.11 EGO54862.1 - 2 8.6 6.1 0.66 10.2 1.7 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF2434 PF10361.9 EGO54863.1 - 8.2e-134 445.2 8.9 1e-133 444.9 8.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) zf-C2H2 PF00096.26 EGO54866.1 - 1.3e-06 28.6 10.7 0.0031 17.9 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO54866.1 - 0.00013 22.5 10.0 0.026 15.3 2.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGO54866.1 - 0.00025 21.3 3.5 0.00025 21.3 3.5 2.7 3 0 0 3 3 3 1 Zinc-finger double domain TylF PF05711.11 EGO54866.1 - 0.16 11.2 0.2 0.61 9.3 0.0 1.8 2 0 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) zf-H2C2_5 PF13909.6 EGO54866.1 - 0.89 9.4 4.1 2.8 7.8 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain RPN2_C PF18004.1 EGO54866.1 - 1 9.2 2.9 2.3 8.1 2.9 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain OTT_1508_deam PF14441.6 EGO54868.1 - 6.3e-19 67.7 0.1 1.2e-18 66.8 0.1 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase FAP206 PF12018.8 EGO54868.1 - 0.075 12.5 0.3 0.23 10.9 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function zf-C2H2 PF00096.26 EGO54869.1 - 3.7e-05 23.9 8.7 0.0003 21.1 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO54869.1 - 0.00013 22.2 2.1 0.0043 17.4 0.9 2.9 2 0 0 2 2 2 1 Zinc-finger double domain Sina PF03145.16 EGO54869.1 - 0.0016 18.5 0.5 0.0021 18.0 0.5 1.2 1 0 0 1 1 1 1 Seven in absentia protein family zf-C2H2_4 PF13894.6 EGO54869.1 - 0.0029 18.3 7.8 0.13 13.2 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger SR-25 PF10500.9 EGO54869.1 - 1.5 8.4 14.4 0.67 9.5 12.3 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CFEM PF05730.11 EGO54870.1 - 2.2e-10 40.4 8.1 5.1e-10 39.3 8.1 1.6 1 0 0 1 1 1 1 CFEM domain FAD_binding_3 PF01494.19 EGO54871.1 - 5.4e-28 98.2 0.0 7.7e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGO54871.1 - 0.095 12.3 1.5 2.9 7.4 0.1 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Glyco_hydro_7 PF00840.20 EGO54872.1 - 3.8e-150 500.4 5.2 4.4e-150 500.2 5.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF2963 PF11178.8 EGO54872.1 - 0.15 11.7 0.2 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) DUF1775 PF07987.11 EGO54876.1 - 0.18 12.0 1.7 2.3 8.5 0.9 3.0 2 1 1 3 3 3 0 Domain of unkown function (DUF1775) EI24 PF07264.11 EGO54877.1 - 5.1e-08 33.4 13.6 8.9e-08 32.6 13.6 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Fungal_trans PF04082.18 EGO54878.1 - 2.8e-12 46.3 0.2 2.8e-12 46.3 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO54878.1 - 1.6e-07 31.4 9.1 2.8e-07 30.6 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Senescence_reg PF04520.13 EGO54878.1 - 1.3 9.9 5.4 8.9 7.1 0.6 2.3 2 0 0 2 2 2 0 Senescence regulator 2-Hacid_dh_C PF02826.19 EGO54879.1 - 1.6e-41 141.7 0.0 1.1e-26 93.3 0.0 2.8 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 EGO54879.1 - 0.017 15.6 0.0 0.031 14.8 0.0 1.5 1 1 0 1 1 1 0 XdhC Rossmann domain 2-Hacid_dh PF00389.30 EGO54879.1 - 0.036 13.7 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 EGO54879.1 - 0.066 13.8 0.0 0.15 12.6 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.24 EGO54879.1 - 0.07 13.5 0.3 0.56 10.6 0.1 2.2 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EGO54879.1 - 0.17 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DSPc PF00782.20 EGO54880.1 - 1.1e-18 67.3 0.0 1.3e-16 60.6 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGO54880.1 - 0.0041 16.7 0.4 0.0088 15.6 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Cyt-b5 PF00173.28 EGO54882.1 - 8.7e-11 41.8 0.0 1.6e-08 34.6 0.0 3.6 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain E1-E2_ATPase PF00122.20 EGO54883.1 - 9.6e-37 126.2 15.8 4.7e-30 104.4 0.2 3.4 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGO54883.1 - 1e-23 84.0 6.0 1e-23 84.0 6.0 2.5 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGO54883.1 - 2.9e-18 66.9 0.0 7.9e-15 55.7 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGO54883.1 - 5.7e-18 64.8 0.0 1.2e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGO54883.1 - 2.1e-15 56.2 0.0 5e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGO54883.1 - 0.0026 17.6 0.0 0.035 13.9 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 EGO54883.1 - 0.12 12.2 0.2 0.29 11.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) MFS_1 PF07690.16 EGO54884.1 - 3.7e-25 88.6 61.4 3e-20 72.4 41.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BTB PF00651.31 EGO54885.1 - 4.6e-25 88.0 0.0 1e-14 54.7 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain Viral_DNA_bi PF02236.17 EGO54886.1 - 0.095 12.9 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Viral DNA-binding protein, all alpha domain DEC-1_N PF04625.13 EGO54886.1 - 1.6 7.7 10.4 2.9 6.8 10.4 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Cu-oxidase_2 PF07731.14 EGO54887.1 - 3.2e-28 98.2 0.9 3.5e-25 88.3 1.1 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGO54887.1 - 3.4e-20 72.2 0.7 1.6e-19 70.1 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EGO54887.1 - 4.1e-05 23.7 0.0 0.00068 19.8 0.0 2.9 3 1 0 3 3 3 1 Multicopper oxidase Rrp40_N PF18311.1 EGO54887.1 - 0.16 12.0 0.9 22 5.1 0.4 2.7 3 0 0 3 3 3 0 Exosome complex exonuclease Rrp40 N-terminal domain Glyco_transf_20 PF00982.21 EGO54888.1 - 1.6e-147 492.0 0.0 2.2e-147 491.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGO54888.1 - 1.3e-71 240.5 0.0 2e-71 239.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase GFA PF04828.14 EGO54889.1 - 3.5e-10 40.1 1.7 3.5e-10 40.1 1.7 1.8 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_2 PF00891.18 EGO54890.1 - 6.6e-21 74.6 0.1 1.4e-20 73.5 0.1 1.5 1 1 0 1 1 1 1 O-methyltransferase domain DIOX_N PF14226.6 EGO54891.1 - 9.1e-23 81.3 0.0 2e-22 80.2 0.0 1.5 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGO54891.1 - 1.7e-21 76.6 0.0 6.2e-21 74.8 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EGO54891.1 - 0.14 13.0 0.0 0.3 12.0 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DHDPS PF00701.22 EGO54892.1 - 9.9e-25 86.8 0.0 1.3e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family RNase_T PF00929.24 EGO54893.1 - 0.00026 21.6 0.0 0.0034 17.9 0.0 2.4 1 1 1 2 2 2 1 Exonuclease DUF2201_N PF13203.6 EGO54893.1 - 9.7 5.7 8.7 5.1 6.6 2.7 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain zf-C2H2 PF00096.26 EGO54894.1 - 0.0014 19.0 6.0 0.38 11.3 0.8 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO54894.1 - 0.0055 17.4 3.3 3.9 8.6 0.3 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-TRAF PF02176.18 EGO54894.1 - 0.18 12.5 1.4 12 6.7 0.2 2.5 2 0 0 2 2 2 0 TRAF-type zinc finger zf-H2C2_5 PF13909.6 EGO54894.1 - 1.2 8.9 9.0 0.095 12.5 0.9 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain INCENP_ARK-bind PF03941.15 EGO54895.1 - 0.027 14.4 2.3 0.14 12.1 2.8 2.0 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region UL42 PF17638.2 EGO54895.1 - 8 6.5 9.2 25 4.9 9.2 1.9 1 0 0 1 1 1 0 HCMV UL42 F-box PF00646.33 EGO54896.1 - 2.1e-05 24.3 2.1 0.00032 20.5 0.3 3.0 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 EGO54896.1 - 0.0014 18.9 0.2 9 6.9 0.0 4.1 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGO54896.1 - 0.019 14.8 0.9 0.046 13.6 0.2 1.9 2 0 0 2 2 2 0 F-box-like UNC119_bdg PF15435.6 EGO54897.1 - 0.12 11.9 0.1 0.93 9.0 0.0 1.9 2 0 0 2 2 2 0 UNC119-binding protein C5orf30 homologue Inhibitor_I36 PF03995.13 EGO54898.1 - 0.0069 16.3 2.9 0.0069 16.3 2.9 2.2 2 1 1 3 3 3 1 Peptidase inhibitor family I36 ABC_membrane PF00664.23 EGO54900.1 - 2.8e-44 151.8 11.6 3.5e-44 151.5 11.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGO54900.1 - 9.3e-34 116.9 0.0 3.8e-33 114.9 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 EGO54900.1 - 1.6e-05 25.4 0.0 3.9e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EGO54900.1 - 3e-05 23.6 0.0 0.014 14.8 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGO54900.1 - 0.00023 21.5 0.0 0.0014 18.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGO54900.1 - 0.00073 19.6 0.0 0.0043 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EGO54900.1 - 0.002 18.0 0.0 0.018 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EGO54900.1 - 0.0058 17.1 0.0 0.058 13.8 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGO54900.1 - 0.0081 15.9 0.0 0.02 14.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGO54900.1 - 0.0089 15.9 0.0 0.028 14.3 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 EGO54900.1 - 0.01 15.2 0.0 0.034 13.4 0.0 1.9 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 EGO54900.1 - 0.016 15.0 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGO54900.1 - 0.017 15.2 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EGO54900.1 - 0.023 14.9 0.0 0.059 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EGO54900.1 - 0.024 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 EGO54900.1 - 0.027 14.4 0.1 0.085 12.8 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 EGO54900.1 - 0.042 13.6 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 1 0 Cytidylate kinase AAA_25 PF13481.6 EGO54900.1 - 0.052 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGO54900.1 - 0.069 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGO54900.1 - 0.081 13.1 0.0 0.24 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 EGO54900.1 - 0.083 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 EGO54900.1 - 0.092 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGO54900.1 - 0.095 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EGO54900.1 - 0.1 13.2 0.0 0.45 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGO54900.1 - 0.12 12.3 0.0 0.42 10.5 0.0 2.0 2 1 0 2 2 1 0 ATPase domain predominantly from Archaea SbcCD_C PF13558.6 EGO54900.1 - 0.15 12.3 0.5 2 8.7 0.5 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Kinesin PF00225.23 EGO54901.1 - 2.1e-33 115.7 0.2 3.6e-33 114.9 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain HHH_5 PF14520.6 EGO54901.1 - 0.00013 22.5 0.3 0.25 12.0 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH_3 PF12836.7 EGO54901.1 - 0.0053 17.0 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif MIT PF04212.18 EGO54901.1 - 0.033 14.2 0.1 0.16 12.1 0.1 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain PI3K_1B_p101 PF10486.9 EGO54901.1 - 0.083 10.7 2.1 0.18 9.6 2.1 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit HHH PF00633.23 EGO54901.1 - 0.13 12.2 0.1 6.2 6.9 0.0 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix motif TPR_14 PF13428.6 EGO54901.1 - 0.32 11.9 0.1 0.32 11.9 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat AIM24 PF01987.17 EGO54902.1 - 6.7e-49 166.4 0.0 8.8e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 HhH-GPD PF00730.25 EGO54903.1 - 1.7e-06 28.4 0.1 4.7e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGO54903.1 - 0.0028 17.5 0.0 0.0092 15.8 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif Whib PF02467.16 EGO54903.1 - 0.023 15.3 2.0 0.039 14.5 0.2 2.4 2 0 0 2 2 2 0 Transcription factor WhiB HHH_2 PF12826.7 EGO54903.1 - 0.039 14.1 0.0 8 6.7 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif CsgF PF10614.9 EGO54903.1 - 0.061 13.5 5.7 0.15 12.3 5.7 1.7 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein DUF3439 PF11921.8 EGO54903.1 - 0.093 12.7 13.1 2.4 8.1 1.2 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Coilin_N PF15862.5 EGO54903.1 - 0.42 10.4 3.9 1.7e+02 2.0 4.5 4.0 4 1 1 5 5 5 0 Coilin N-terminus YdfA_immunity PF12127.8 EGO54903.1 - 1.2 8.1 7.4 2.2 7.2 7.4 1.3 1 0 0 1 1 1 0 SigmaW regulon antibacterial COMPASS-Shg1 PF05205.12 EGO54903.1 - 2 9.1 6.3 5.4 7.8 6.3 1.7 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF853 PF05872.12 EGO54903.1 - 5.7 5.4 9.9 0.44 9.1 3.9 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) NUDIX_4 PF14815.6 EGO54904.1 - 5.1e-23 81.2 0.1 1.1e-22 80.0 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 EGO54904.1 - 1.8e-13 50.8 0.0 3.5e-13 49.9 0.0 1.6 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein EndIII_4Fe-2S PF10576.9 EGO54904.1 - 0.037 14.4 2.0 0.16 12.4 2.0 2.2 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Mucin PF01456.17 EGO54904.1 - 1.8 8.6 22.1 4.4 7.3 22.1 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 EGO54904.1 - 2.2 6.3 6.8 3 5.8 6.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus zf-C2H2_jaz PF12171.8 EGO54906.1 - 0.029 14.7 2.9 0.051 13.9 2.9 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 EGO54906.1 - 0.033 14.0 4.5 0.057 13.2 4.5 1.4 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 EGO54906.1 - 0.54 10.8 3.7 0.99 10.0 3.7 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 EGO54908.1 - 0.0042 17.4 10.4 0.019 15.4 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EGO54908.1 - 0.23 11.8 2.0 0.75 10.2 1.2 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EGO54908.1 - 1.4 9.9 12.2 3.6 8.7 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger QWRF PF04484.12 EGO54909.1 - 0.72 9.5 6.6 0.84 9.3 6.6 1.0 1 0 0 1 1 1 0 QWRF family zf-C2H2 PF00096.26 EGO54910.1 - 3.5e-08 33.5 7.1 6.8e-05 23.1 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO54910.1 - 2.7e-07 30.8 4.4 0.0013 19.4 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 EGO54910.1 - 0.00053 20.0 4.9 0.19 11.8 1.2 2.7 3 0 0 3 3 3 2 BED zinc finger zf-C2H2_jaz PF12171.8 EGO54910.1 - 0.0008 19.6 1.6 0.023 15.0 0.9 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGO54910.1 - 0.0018 18.6 0.8 4 7.9 1.3 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 EGO54910.1 - 0.018 14.8 8.2 1.1 9.1 2.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 EGO54910.1 - 0.022 15.1 0.3 0.74 10.2 0.0 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 EGO54910.1 - 0.028 15.1 0.2 2.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 EGO54910.1 - 0.039 14.3 0.5 0.68 10.3 0.2 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-RING_7 PF02591.15 EGO54910.1 - 0.046 13.9 0.1 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain DUF3449 PF11931.8 EGO54910.1 - 0.047 13.5 0.4 0.047 13.5 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) FOXP-CC PF16159.5 EGO54910.1 - 0.22 12.2 3.3 1.6 9.4 0.2 2.3 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 EGO54910.1 - 2.2 8.8 14.6 21 5.8 0.1 3.9 3 1 0 3 3 3 0 Zinc-finger double domain RNase_H PF00075.24 EGO54912.1 - 0.00071 19.8 2.8 0.015 15.5 0.0 3.1 3 1 1 4 4 4 1 RNase H NPR3 PF03666.13 EGO54912.1 - 0.079 11.7 4.0 0.13 11.0 4.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ctr PF04145.15 EGO54912.1 - 0.26 11.9 1.7 0.79 10.3 1.7 1.8 1 0 0 1 1 1 0 Ctr copper transporter family CDC45 PF02724.14 EGO54912.1 - 1.9 6.7 13.0 3.6 5.8 13.0 1.4 1 0 0 1 1 1 0 CDC45-like protein MDM10 PF12519.8 EGO54912.1 - 4.9 5.9 7.8 7.9 5.2 7.8 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Atg14 PF10186.9 EGO54912.1 - 5.2 6.1 13.2 7.9 5.5 13.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Trypsin_2 PF13365.6 EGO54915.1 - 1.3e-08 35.9 0.1 2.8e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGO54915.1 - 4.5e-05 23.4 0.0 7.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin NUDIX PF00293.28 EGO54917.1 - 3.7e-08 33.5 0.1 1.5e-07 31.5 0.1 1.9 2 0 0 2 2 2 1 NUDIX domain DUF2650 PF10853.8 EGO54917.1 - 0.06 13.1 0.4 0.11 12.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) MHYT PF03707.16 EGO54918.1 - 2.7e-14 53.1 26.3 4.3e-07 30.0 3.3 4.5 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat FSH1 PF03959.13 EGO54919.1 - 4.1e-22 78.9 0.0 1.5e-21 77.0 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ketoacyl-synt PF00109.26 EGO54921.1 - 3.7e-76 256.0 0.0 7.6e-76 255.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EGO54921.1 - 8.2e-62 208.3 0.1 2.7e-61 206.6 0.0 2.0 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EGO54921.1 - 4.2e-57 194.0 0.0 6.6e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EGO54921.1 - 1e-39 136.6 1.1 5.7e-22 78.3 0.1 2.5 2 0 0 2 2 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EGO54921.1 - 1e-31 109.4 0.0 4.1e-31 107.4 0.0 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGO54921.1 - 3.7e-16 59.6 0.0 1.3e-15 57.8 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EGO54921.1 - 8.6e-15 54.7 0.0 2.6e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO54921.1 - 7.8e-11 42.0 0.0 2.4e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 EGO54921.1 - 1.7e-08 34.7 0.6 5.1e-08 33.1 0.6 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 EGO54921.1 - 8e-08 32.3 0.7 7.2e-07 29.3 0.1 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO54921.1 - 1e-05 26.6 0.0 5.6e-05 24.2 0.0 2.2 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 EGO54921.1 - 3e-05 23.5 0.0 3e-05 23.5 0.0 2.5 3 0 0 3 3 2 1 Thiolase, N-terminal domain Epimerase PF01370.21 EGO54921.1 - 0.0013 18.2 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EGO54921.1 - 0.035 14.4 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ACP_syn_III PF08545.10 EGO54921.1 - 0.036 13.9 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Polysacc_synt_2 PF02719.15 EGO54921.1 - 0.07 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_N PF08240.12 EGO54921.1 - 0.11 12.4 1.0 0.25 11.3 1.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Fer4 PF00037.27 EGO54923.1 - 4.1e-14 51.7 16.4 5.8e-08 32.2 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EGO54923.1 - 5.3e-13 49.3 10.7 8.6e-13 48.7 10.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EGO54923.1 - 7.1e-11 42.9 7.3 7.7e-05 23.6 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EGO54923.1 - 3.5e-10 39.9 4.7 7.4e-05 22.8 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGO54923.1 - 4.5e-09 36.3 21.3 8.8e-07 28.9 12.3 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGO54923.1 - 2e-08 34.3 10.1 4.1e-08 33.3 10.2 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGO54923.1 - 3.8e-07 30.5 19.8 0.00013 22.3 11.9 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 EGO54923.1 - 7.5e-07 29.0 16.9 0.0002 21.3 5.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EGO54923.1 - 9.6e-07 28.5 12.2 0.0028 17.7 3.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EGO54923.1 - 2e-05 24.7 11.6 0.00066 20.0 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EGO54923.1 - 0.00014 22.3 12.2 0.025 15.1 13.3 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EGO54923.1 - 0.0058 16.8 5.6 0.74 10.1 0.5 2.3 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 EGO54923.1 - 0.032 14.4 9.3 0.5 10.6 1.7 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 EGO54923.1 - 0.035 14.2 4.7 0.23 11.6 0.3 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_13 PF13370.6 EGO54923.1 - 0.065 13.8 14.8 0.8 10.3 4.0 2.7 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 EGO54923.1 - 0.085 13.8 16.6 0.4 11.7 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain EPF PF17181.4 EGO54923.1 - 0.4 10.7 5.8 0.17 11.9 0.6 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins Fer4_22 PF17179.4 EGO54923.1 - 0.47 11.3 12.1 2.7 8.9 2.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain PP-binding PF00550.25 EGO54924.1 - 4.8e-12 46.1 0.1 6.8e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EGO54924.1 - 5.7e-05 23.3 0.3 7.5e-05 22.9 0.3 1.2 1 0 0 1 1 1 1 Acyl-carrier zf-CCCH PF00642.24 EGO54925.1 - 4.5e-11 42.4 8.0 1.1e-05 25.1 2.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGO54925.1 - 2.6e-10 39.8 10.2 1.7e-05 24.5 3.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGO54925.1 - 2.9e-10 39.9 16.5 4.2e-05 23.5 3.5 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EGO54925.1 - 6.9e-09 36.4 6.0 0.00012 22.7 0.4 2.5 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 EGO54925.1 - 9.1e-06 25.9 2.6 1.3e-05 25.3 1.7 1.6 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGO54925.1 - 0.0057 17.1 16.8 0.19 12.3 2.7 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger p450 PF00067.22 EGO54926.1 - 6.9e-49 166.8 0.0 8.7e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ScsC_N PF18312.1 EGO54926.1 - 0.035 13.9 0.1 0.12 12.2 0.1 1.9 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Hemerythrin PF01814.23 EGO54927.1 - 6.1e-13 49.5 1.9 8.8e-13 49.0 1.9 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF1031 PF06275.11 EGO54927.1 - 0.032 14.5 0.1 0.084 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) DUF3445 PF11927.8 EGO54928.1 - 1e-78 264.1 0.0 1.5e-78 263.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF3290 PF11694.8 EGO54928.1 - 0.0097 15.9 0.1 0.017 15.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3290) Fungal_trans_2 PF11951.8 EGO54930.1 - 6e-05 22.0 0.0 0.0001 21.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 EGO54932.1 - 6.1e-52 176.9 0.0 7.5e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4572 PF15139.6 EGO54932.1 - 0.12 12.3 0.3 0.18 11.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) DUF2196 PF09962.9 EGO54933.1 - 6.5e-23 80.5 4.4 1e-22 79.8 4.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) zf-Di19 PF05605.12 EGO54933.1 - 0.092 13.1 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF3439 PF11921.8 EGO54933.1 - 0.19 11.7 4.1 0.33 10.9 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF423 PF04241.15 EGO54934.1 - 1.1e-23 83.2 1.5 2e-23 82.4 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Bax1-I PF01027.20 EGO54934.1 - 0.0047 16.8 5.8 0.0051 16.7 5.8 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 NmrA PF05368.13 EGO54935.1 - 1.8e-17 63.7 0.0 2.5e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO54935.1 - 4.2e-11 43.1 0.0 8.2e-11 42.1 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGO54935.1 - 0.0023 17.1 0.0 0.0055 15.9 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 EGO54935.1 - 0.047 14.1 0.0 0.099 13.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AMP-binding PF00501.28 EGO54936.1 - 1.3e-28 99.8 0.0 3e-28 98.6 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EGO54936.1 - 3.3e-28 98.6 0.0 5.8e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EGO54936.1 - 3.8e-07 29.8 0.0 8.6e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EGO54936.1 - 1.7e-05 25.1 0.0 5.7e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 EGO54936.1 - 0.041 13.0 0.0 0.18 10.9 0.0 2.0 3 0 0 3 3 3 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGO54936.1 - 0.058 12.5 0.0 0.23 10.5 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Pentapeptide PF00805.22 EGO54936.1 - 0.18 11.5 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) Sugar_tr PF00083.24 EGO54937.1 - 9.9e-66 222.4 17.9 1.2e-65 222.2 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO54937.1 - 5.4e-20 71.6 30.7 5.4e-20 71.6 30.7 2.1 1 1 2 3 3 3 1 Major Facilitator Superfamily YtpI PF14007.6 EGO54937.1 - 2.4 8.4 6.4 1 9.5 0.5 2.9 2 1 0 2 2 2 0 YtpI-like protein Glyco_hydro_10 PF00331.20 EGO54939.1 - 5.6e-100 334.6 0.5 6.9e-100 334.3 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 EGO54939.1 - 1.1e-12 47.6 12.1 3.6e-12 46.0 12.1 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.12 EGO54939.1 - 0.1 12.9 2.0 0.21 11.9 2.0 1.5 1 0 0 1 1 1 0 Toxin 7 Acetyltransf_3 PF13302.7 EGO54940.1 - 1.2e-15 58.4 0.0 1.5e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO54940.1 - 0.00052 20.2 0.0 0.0012 19.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGO54940.1 - 0.15 12.0 0.1 0.89 9.6 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein Peptidase_M28 PF04389.17 EGO54942.1 - 2.1e-39 135.3 0.0 3e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGO54942.1 - 2.8e-09 37.0 0.1 5.2e-09 36.1 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 EGO54942.1 - 0.0094 15.4 0.3 0.27 10.7 0.1 2.4 2 0 0 2 2 2 1 Nicastrin Peptidase_M42 PF05343.14 EGO54942.1 - 0.08 12.0 0.0 0.97 8.4 0.0 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Glyco_transf_64 PF09258.10 EGO54942.1 - 0.082 12.2 0.4 1.5 8.1 0.2 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 64 domain CK2S PF15011.6 EGO54944.1 - 0.083 12.8 0.9 0.17 11.8 0.9 1.6 1 1 0 1 1 1 0 Casein Kinase 2 substrate OPT PF03169.15 EGO54945.1 - 2.6e-164 548.3 44.6 3e-164 548.1 44.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1989 PF09347.10 EGO54946.1 - 1.4e-63 213.5 0.0 1.7e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) RPE65 PF03055.15 EGO54947.1 - 5.2e-118 395.2 0.0 6e-118 395.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Abhydrolase_3 PF07859.13 EGO54948.1 - 9.5e-32 110.6 0.0 1.3e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EGO54948.1 - 0.023 13.6 0.2 0.038 12.9 0.2 1.3 1 0 0 1 1 1 0 Carboxylesterase family Aminotran_3 PF00202.21 EGO54949.1 - 9e-52 176.1 0.0 2e-51 175.0 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-III WD40 PF00400.32 EGO54951.1 - 1.7e-10 41.3 7.8 0.028 15.3 0.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat SH PF01445.17 EGO54951.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Viral small hydrophobic protein GRAM PF02893.20 EGO54952.1 - 9.3e-31 106.1 0.9 3.3e-20 72.1 0.0 3.3 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 EGO54952.1 - 2.9e-29 101.9 0.0 6.3e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 EGO54952.1 - 1.2e-16 61.1 0.2 8.2e-16 58.4 0.1 2.5 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 EGO54952.1 - 4.6e-06 26.8 0.2 1.2e-05 25.5 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EGO54952.1 - 1.7e-05 25.1 4.9 3.1e-05 24.4 1.6 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.18 EGO54952.1 - 0.00039 19.3 0.1 0.00092 18.1 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.6 EGO54952.1 - 0.00075 19.6 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EGO54952.1 - 0.0038 17.6 0.1 0.012 16.0 0.1 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 EGO54952.1 - 0.0047 17.2 0.1 0.017 15.4 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 EGO54952.1 - 0.0059 16.9 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Plant pleckstrin homology-like region NIF PF03031.18 EGO54953.1 - 9.5e-31 106.7 0.0 2e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 EGO54953.1 - 1.6e-06 28.4 0.0 4.6e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGO54953.1 - 8.6e-06 25.6 0.0 3.8e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 EGO54953.1 - 0.02 14.8 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain GRIM-19 PF06212.12 EGO54954.1 - 1e-22 80.5 0.0 1.8e-22 79.7 0.0 1.4 1 1 0 1 1 1 1 GRIM-19 protein Helicase_C_2 PF13307.6 EGO54956.1 - 1.1e-64 217.7 0.1 3.8e-64 216.0 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 EGO54956.1 - 8.2e-51 172.1 0.0 1.5e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 HemX PF04375.14 EGO54956.1 - 0.14 11.4 1.7 0.26 10.5 1.7 1.4 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4110 PF13422.6 EGO54956.1 - 5.8 7.1 12.5 5 7.3 9.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) Pkinase PF00069.25 EGO54957.1 - 2.3e-42 145.2 0.0 3.3e-39 134.8 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO54957.1 - 4.9e-13 49.0 0.0 3.5e-07 29.8 0.0 3.7 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 EGO54957.1 - 0.0012 18.9 0.0 0.085 12.8 0.0 2.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGO54957.1 - 0.083 12.5 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EGO54957.1 - 0.13 11.6 0.0 7.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like SDA1 PF05285.12 EGO54957.1 - 7 6.0 22.9 0.13 11.6 16.0 1.7 2 0 0 2 2 2 0 SDA1 FAM76 PF16046.5 EGO54957.1 - 7.3 5.9 11.2 11 5.2 11.2 1.2 1 0 0 1 1 1 0 FAM76 protein PPL5 PF18168.1 EGO54957.1 - 8 5.7 8.5 13 4.9 8.5 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Cnd1_N PF12922.7 EGO54958.1 - 1.5e-59 200.6 0.1 1.5e-59 200.6 0.1 2.8 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 EGO54958.1 - 1.2e-50 171.7 0.7 5.9e-45 153.2 0.0 3.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGO54958.1 - 8.7e-12 44.2 4.1 0.047 14.0 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 EGO54958.1 - 1.1e-10 41.7 1.0 6.9e-05 23.2 0.0 4.9 5 1 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 EGO54958.1 - 2.9e-06 27.7 3.1 0.29 11.7 0.1 5.3 5 0 0 5 5 5 2 HEAT-like repeat RTP1_C1 PF10363.9 EGO54958.1 - 1e-05 25.7 0.1 0.038 14.2 0.0 3.5 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 EGO54958.1 - 0.00023 20.4 0.3 0.00023 20.4 0.3 3.8 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 EGO54958.1 - 0.001 17.7 7.2 0.0095 14.5 0.3 3.3 3 1 0 3 3 3 2 Adaptin N terminal region DUF3458_C PF17432.2 EGO54958.1 - 0.014 14.8 0.6 0.044 13.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3458_C) ARM repeats FtsX PF02687.21 EGO54961.1 - 0.12 12.9 5.0 0.18 12.3 5.0 1.2 1 0 0 1 1 1 0 FtsX-like permease family EphA2_TM PF14575.6 EGO54961.1 - 0.3 12.0 0.0 0.3 12.0 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3431 PF11913.8 EGO54962.1 - 2.1e-88 295.7 0.0 2.4e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Podoplanin PF05808.11 EGO54963.1 - 0.00025 21.2 1.7 0.00044 20.4 1.7 1.3 1 0 0 1 1 1 1 Podoplanin Rax2 PF12768.7 EGO54963.1 - 0.0016 17.9 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Velvet PF11754.8 EGO54963.1 - 0.005 16.8 0.5 0.0068 16.4 0.5 1.3 1 0 0 1 1 1 1 Velvet factor TMEM154 PF15102.6 EGO54963.1 - 0.01 15.7 0.2 0.021 14.7 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF4690 PF15756.5 EGO54963.1 - 0.02 15.5 3.2 0.073 13.7 3.1 2.0 1 1 0 1 1 1 0 Small Novel Rich in Cartilage Stevor PF17410.2 EGO54963.1 - 0.064 12.8 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF1656 PF07869.12 EGO54963.1 - 0.12 12.4 1.2 0.26 11.3 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) MSA-2c PF12238.8 EGO54963.1 - 0.26 11.3 8.7 3.3 7.6 6.5 2.5 2 0 0 2 2 2 0 Merozoite surface antigen 2c Alpha_GJ PF03229.13 EGO54963.1 - 7.1 7.2 13.8 19 5.8 13.5 1.9 1 1 0 1 1 1 0 Alphavirus glycoprotein J Tom5 PF10642.9 EGO54965.1 - 0.039 14.0 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase MFS_1 PF07690.16 EGO54966.1 - 8e-09 34.9 19.0 2.4e-08 33.3 19.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Evr1_Alr PF04777.13 EGO54967.1 - 1.1e-26 93.2 0.1 1.5e-26 92.8 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Proteasome PF00227.26 EGO54968.1 - 5.7e-48 162.9 0.3 6.5e-48 162.7 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.11 EGO54969.1 - 5.7e-38 130.8 0.1 2.3e-24 86.6 0.1 3.8 4 0 0 4 4 4 2 Cyclin HA2 PF04408.23 EGO54969.1 - 2.2 8.6 4.6 71 3.7 0.1 3.5 3 0 0 3 3 3 0 Helicase associated domain (HA2) Phage_Gp23 PF10669.9 EGO54969.1 - 2.4 8.5 8.0 9.7 6.5 0.3 2.7 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) Sugar_tr PF00083.24 EGO54972.1 - 9.1e-92 308.3 23.8 1.2e-91 307.9 23.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO54972.1 - 3.8e-15 55.7 47.2 5.2e-08 32.2 12.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.28 EGO54972.1 - 0.092 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme YjcB PF15940.5 EGO54972.1 - 2.8 8.2 5.4 18 5.6 0.1 3.3 3 0 0 3 3 3 0 Family of unknown function DUF3445 PF11927.8 EGO54973.1 - 9.5e-63 211.8 0.0 1.1e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) ADH_zinc_N PF00107.26 EGO54974.1 - 5.6e-25 87.8 0.9 8.5e-25 87.2 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO54974.1 - 9.8e-17 62.3 0.0 3.1e-16 60.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO54974.1 - 1.2e-09 38.0 0.0 3.5e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 EGO54974.1 - 5.4e-05 23.4 0.0 0.00014 22.1 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain ADH_N_2 PF16884.5 EGO54974.1 - 0.074 12.9 0.0 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase AstE_AspA PF04952.14 EGO54974.1 - 0.091 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Hexapep PF00132.24 EGO54976.1 - 7e-13 47.8 9.1 4.1e-09 35.8 3.3 3.5 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGO54976.1 - 1.1e-12 47.5 9.0 3.2e-10 39.6 2.6 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 EGO54976.1 - 1.9e-11 44.0 0.2 3.2e-11 43.3 0.2 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase HET PF06985.11 EGO54977.1 - 2.7e-22 79.7 0.0 5.8e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_31 PF01055.26 EGO54978.1 - 2.8e-149 498.1 2.4 3.5e-149 497.7 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EGO54978.1 - 5.2e-37 126.6 0.4 1e-36 125.6 0.4 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EGO54978.1 - 1.4e-12 47.8 1.0 4.5e-12 46.1 0.6 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EGO54978.1 - 0.1 12.9 0.1 0.36 11.1 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Cu-oxidase_2 PF07731.14 EGO54981.1 - 1.2e-37 128.7 3.4 2.6e-36 124.4 0.3 3.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EGO54981.1 - 6.4e-32 110.9 0.0 1.1e-31 110.1 0.0 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGO54981.1 - 4.5e-24 84.7 0.1 4.5e-24 84.7 0.1 3.1 4 0 0 4 4 4 1 Multicopper oxidase adh_short PF00106.25 EGO54982.1 - 2.5e-19 69.5 0.0 1.3e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO54982.1 - 2.3e-10 40.4 0.0 5.6e-08 32.6 0.0 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO54982.1 - 5.6e-07 29.7 0.1 9.4e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 KR domain kleA_kleC PF17383.2 EGO54984.1 - 1.8 8.9 4.9 1.4 9.3 2.6 1.9 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A NmrA PF05368.13 EGO54986.1 - 2.3e-14 53.5 0.0 4.4e-14 52.6 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO54986.1 - 5e-14 52.6 0.0 1.3e-13 51.3 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO54986.1 - 0.04 13.4 0.0 0.34 10.3 0.0 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Tcp11 PF05794.13 EGO54987.1 - 2.6e-100 336.6 0.3 2.6e-100 336.6 0.3 2.1 2 0 0 2 2 2 1 T-complex protein 11 SIT PF15330.6 EGO54988.1 - 0.06 13.8 0.0 0.096 13.1 0.0 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Corona_M PF01635.18 EGO54988.1 - 1.1 8.5 4.2 0.36 10.1 1.0 1.7 2 0 0 2 2 2 0 Coronavirus M matrix/glycoprotein SQHop_cyclase_N PF13249.6 EGO54989.1 - 0.019 14.1 0.0 1.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EGO54989.1 - 0.039 13.7 0.2 0.38 10.5 0.0 2.9 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat BSP_II PF05432.11 EGO54989.1 - 0.12 12.1 2.8 0.26 10.9 2.8 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAD_binding_4 PF01565.23 EGO54990.1 - 1e-27 96.6 0.2 1.8e-27 95.8 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.22 EGO54991.1 - 8.2e-37 127.0 0.9 2.4e-36 125.5 0.9 1.6 1 1 0 1 1 1 1 Cytochrome P450 Mucin PF01456.17 EGO54992.1 - 0.0066 16.4 11.2 0.009 16.0 11.2 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein Lgl_C PF08596.10 EGO54993.1 - 2.1e-130 434.9 0.0 3.8e-130 434.1 0.0 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 EGO54993.1 - 6.3e-07 29.6 0.0 0.0049 17.1 0.0 4.8 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO54993.1 - 0.0014 19.4 11.5 0.0042 17.9 0.3 5.7 6 0 0 6 6 6 1 WD domain, G-beta repeat WD40_like PF17005.5 EGO54993.1 - 0.0036 16.7 0.0 0.0086 15.4 0.0 1.6 1 0 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 EGO54993.1 - 0.012 14.3 0.0 2.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Nucleoporin Nup120/160 DUF1664 PF07889.12 EGO54994.1 - 0.85 9.7 2.7 1.7 8.7 2.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EGO54994.1 - 0.96 9.5 2.7 1.8e+02 2.2 0.2 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4611 PF15387.6 EGO54994.1 - 3.4 7.9 10.7 7.3 6.9 5.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Piwi PF02171.17 EGO54995.1 - 1e-82 277.8 0.6 1.6e-82 277.2 0.6 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EGO54995.1 - 5.6e-21 75.6 0.0 1.9e-20 73.9 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EGO54995.1 - 5.4e-15 54.8 0.1 3.1e-14 52.4 0.0 2.3 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EGO54995.1 - 6.3e-11 42.4 0.0 2.2e-10 40.7 0.0 2.1 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 EGO54995.1 - 8.3e-09 35.4 0.1 2e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 EGO54995.1 - 7.3e-07 29.4 0.1 3.2e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Mid domain of argonaute DUF868 PF05910.12 EGO54995.1 - 0.07 12.8 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF868) Herpes_Helicase PF02689.14 EGO54995.1 - 0.11 10.4 0.0 0.17 9.8 0.0 1.1 1 0 0 1 1 1 0 Helicase Suf PF05843.14 EGO54996.1 - 1.1e-97 327.6 7.4 1.5e-93 314.1 0.0 4.4 4 2 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EGO54996.1 - 1.3e-05 25.6 1.5 0.00047 20.7 0.4 4.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO54996.1 - 7.7e-05 23.1 0.0 0.00033 21.1 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGO54996.1 - 0.00029 21.4 1.1 0.00093 19.8 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat HAT PF02184.16 EGO54996.1 - 0.00074 19.4 0.0 0.038 14.0 0.0 3.1 3 0 0 3 3 3 1 HAT (Half-A-TPR) repeat NRDE-2 PF08424.10 EGO54996.1 - 0.038 13.1 3.1 0.23 10.5 0.0 3.4 2 1 1 4 4 4 0 NRDE-2, necessary for RNA interference Globin PF00042.22 EGO54996.1 - 0.053 14.1 0.5 0.35 11.4 0.1 2.5 2 1 0 2 2 2 0 Globin TPR_6 PF13174.6 EGO54996.1 - 9.2 7.1 6.6 2.4 9.0 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ASF1_hist_chap PF04729.13 EGO54997.1 - 2.6e-71 238.6 0.0 3.4e-71 238.2 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.12 EGO54997.1 - 8 4.5 11.9 11 4.1 11.9 1.0 1 0 0 1 1 1 0 Nop14-like family Nrap_D5 PF17406.2 EGO54998.1 - 1.4e-56 190.8 0.7 2.7e-56 189.8 0.2 1.8 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 EGO54998.1 - 4.8e-46 156.3 0.9 1.2e-43 148.5 0.5 2.7 2 1 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 EGO54998.1 - 1.5e-43 148.6 0.0 3.4e-43 147.5 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap PF03813.14 EGO54998.1 - 1.6e-42 145.1 0.0 3.2e-42 144.1 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D4 PF17405.2 EGO54998.1 - 2.7e-37 128.2 0.2 9.8e-32 110.0 0.1 2.4 1 1 1 2 2 2 2 Nrap protein nucleotidyltransferase domain 4 Nrap_D6 PF17407.2 EGO54998.1 - 2e-33 115.5 0.0 4.8e-33 114.2 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 6 TPR_2 PF07719.17 EGO54999.1 - 2.9e-31 105.0 40.7 6.8e-05 22.7 0.0 16.7 17 0 0 17 17 17 8 Tetratricopeptide repeat TPR_19 PF14559.6 EGO54999.1 - 6.2e-31 106.7 26.0 1.2e-05 25.7 0.1 12.2 12 1 1 13 13 12 6 Tetratricopeptide repeat TPR_8 PF13181.6 EGO54999.1 - 2.7e-28 95.8 20.1 0.00024 21.1 0.0 13.0 14 0 0 14 14 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 EGO54999.1 - 1.6e-27 94.1 23.7 4.3e-06 26.3 0.0 13.4 14 0 0 14 14 13 7 Tetratricopeptide repeat TPR_17 PF13431.6 EGO54999.1 - 1.6e-26 90.7 12.4 0.064 13.7 0.0 13.6 13 1 0 13 13 12 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGO54999.1 - 4.3e-25 88.1 44.2 6.4e-06 26.7 0.4 12.1 15 0 0 15 15 12 6 Tetratricopeptide repeat TPR_14 PF13428.6 EGO54999.1 - 4.4e-25 86.2 40.4 0.00038 21.0 0.2 15.4 14 3 4 18 18 15 7 Tetratricopeptide repeat TPR_11 PF13414.6 EGO54999.1 - 5.7e-21 73.9 10.3 0.002 17.8 0.0 8.8 9 0 0 9 9 8 5 TPR repeat TPR_12 PF13424.6 EGO54999.1 - 3.4e-14 52.9 46.9 0.0035 17.6 0.0 13.1 9 4 5 14 14 14 7 Tetratricopeptide repeat TPR_6 PF13174.6 EGO54999.1 - 4.1e-14 52.2 13.4 0.047 14.3 0.0 13.4 15 1 0 15 15 13 2 Tetratricopeptide repeat TPR_22 PF18833.1 EGO54999.1 - 7.7e-07 29.2 0.1 2.8e-06 27.4 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGO54999.1 - 1.1e-06 28.7 17.4 0.00025 21.1 0.1 7.0 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGO54999.1 - 3.1e-06 26.8 30.3 0.0026 17.7 0.1 11.9 15 0 0 15 15 13 2 Tetratricopeptide repeat ChAPs PF09295.10 EGO54999.1 - 0.00028 20.0 1.1 0.85 8.5 0.0 4.2 5 0 0 5 5 5 1 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 EGO54999.1 - 0.018 15.3 26.9 2.7 8.3 0.0 8.1 8 0 0 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EGO54999.1 - 0.022 15.4 33.8 3.4 8.6 0.6 9.4 10 0 0 10 10 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGO54999.1 - 0.024 14.7 0.1 5.9 7.1 0.0 4.2 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat HrpB1_HrpK PF09613.10 EGO54999.1 - 0.047 13.3 0.3 11 5.6 0.1 3.5 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 EGO54999.1 - 0.07 13.5 17.6 11 6.4 0.1 7.1 7 1 1 8 8 8 0 Tetratricopeptide repeat Hemocyanin_N PF03722.14 EGO54999.1 - 0.085 13.4 0.1 0.26 11.8 0.1 1.8 1 0 0 1 1 1 0 Hemocyanin, all-alpha domain HemY_N PF07219.13 EGO54999.1 - 0.088 13.0 8.5 21 5.4 0.1 5.9 5 1 1 6 6 6 0 HemY protein N-terminus TPR_15 PF13429.6 EGO54999.1 - 0.22 10.7 25.9 2.6 7.2 0.0 8.2 6 4 4 10 10 10 0 Tetratricopeptide repeat RPN6_N PF18055.1 EGO54999.1 - 0.44 10.9 5.8 0.71 10.3 0.2 4.3 5 1 1 6 6 5 0 26S proteasome regulatory subunit RPN6 N-terminal domain HBS1_N PF08938.10 EGO54999.1 - 2.7 8.4 6.6 16 5.9 0.2 4.4 4 0 0 4 4 4 0 HBS1 N-terminus DUF4192 PF13830.6 EGO54999.1 - 9.1 6.2 23.3 0.023 14.8 1.3 4.2 4 1 1 5 5 5 0 Domain of unknown function (DUF4192) RMI1_N PF08585.12 EGO55000.1 - 1.7e-58 197.9 0.0 2.1e-58 197.7 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein FXR_C1 PF16096.5 EGO55001.1 - 7.9 6.8 7.9 0.5 10.6 0.7 2.9 2 1 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Polysacc_synt_4 PF04669.13 EGO55002.1 - 1.9e-22 79.7 0.3 7.6e-21 74.5 0.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis AChE_tetra PF08674.10 EGO55002.1 - 0.032 13.9 1.7 0.08 12.7 1.7 1.7 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain ABC_membrane PF00664.23 EGO55003.1 - 1.8e-75 254.2 27.5 2.6e-43 148.7 6.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGO55003.1 - 5e-58 195.5 0.0 2e-27 96.3 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 EGO55003.1 - 4.5e-13 49.1 0.1 0.00044 19.8 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGO55003.1 - 1e-09 38.7 0.8 0.0038 17.1 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGO55003.1 - 3.1e-07 30.0 1.1 0.012 15.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGO55003.1 - 3.6e-07 30.5 0.0 0.1 12.9 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGO55003.1 - 4.4e-06 27.2 0.0 0.066 13.6 0.0 3.1 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGO55003.1 - 6.5e-06 26.1 0.0 0.14 12.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EGO55003.1 - 6.4e-05 23.5 0.3 0.55 10.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGO55003.1 - 0.00095 19.2 0.4 0.75 9.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EGO55003.1 - 0.00097 18.9 0.2 3.2 7.4 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.6 EGO55003.1 - 0.0011 18.6 0.0 1.6 8.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF3987 PF13148.6 EGO55003.1 - 0.0012 18.0 1.1 0.11 11.5 0.0 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF3987) AAA_33 PF13671.6 EGO55003.1 - 0.01 16.0 0.1 5.6 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGO55003.1 - 0.026 14.9 0.0 8.1 6.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 EGO55003.1 - 0.026 14.6 2.5 0.86 9.7 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 EGO55003.1 - 0.031 14.8 0.1 14 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGO55003.1 - 0.039 13.1 0.1 5 6.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 EGO55003.1 - 0.043 13.8 0.0 7.3 6.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EGO55003.1 - 0.053 13.2 0.0 4 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGO55003.1 - 0.079 13.4 0.0 29 5.1 0.0 3.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EGO55003.1 - 0.14 11.4 0.1 15 4.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 EGO55003.1 - 0.16 11.5 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PRK PF00485.18 EGO55003.1 - 0.16 11.7 0.1 2.8 7.6 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ABC_ATPase PF09818.9 EGO55003.1 - 0.23 10.2 4.4 0.32 9.7 0.1 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class ATPase PF06745.13 EGO55003.1 - 1.3 8.3 3.9 13 5.1 0.1 3.0 3 0 0 3 3 3 0 KaiC MFS_1 PF07690.16 EGO55004.1 - 1.2e-34 119.8 30.2 3.9e-33 114.9 11.4 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO55004.1 - 7e-14 51.5 1.3 7e-14 51.5 1.3 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 EGO55004.1 - 0.00078 17.8 0.1 0.00078 17.8 0.1 2.9 2 2 2 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family IncD PF17628.2 EGO55004.1 - 0.69 9.7 2.1 2.6 7.8 2.1 2.0 1 0 0 1 1 1 0 Inclusion membrane protein D AXE1 PF05448.12 EGO55005.1 - 0.0036 16.0 0.1 0.0061 15.3 0.1 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF463 PF04317.12 EGO55005.1 - 0.058 12.3 0.0 0.074 12.0 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 Pyr_redox_2 PF07992.14 EGO55007.1 - 6.8e-27 94.5 0.2 9.1e-27 94.0 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO55007.1 - 2e-05 25.0 0.2 0.00017 22.0 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF1068 PF06364.12 EGO55008.1 - 0.064 13.1 0.0 0.065 13.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) DUF1652 PF07865.11 EGO55009.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) mRNA_triPase PF02940.15 EGO55011.1 - 1.2e-62 211.5 0.7 1.7e-62 211.0 0.7 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain RPN2_C PF18004.1 EGO55012.1 - 5.5e-57 192.2 5.2 1.1e-56 191.1 5.2 1.6 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EGO55012.1 - 8.8e-45 148.9 17.9 2.1e-09 37.3 0.0 8.5 7 0 0 7 7 7 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGO55012.1 - 1.7e-20 73.2 3.1 1.3e-14 54.3 0.0 5.9 4 1 3 7 7 7 2 HEAT repeats HEAT_EZ PF13513.6 EGO55012.1 - 7e-06 26.4 0.6 0.0006 20.3 0.0 4.4 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.22 EGO55012.1 - 6e-05 23.0 3.2 1.8 9.1 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 EGO55012.1 - 0.041 13.9 2.2 1.1 9.3 0.1 3.3 3 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF913 PF06025.12 EGO55012.1 - 1.4 7.8 6.1 27 3.6 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF3188 PF11384.8 EGO55012.1 - 4.3 7.1 5.5 1.9 8.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) Spore_coat_CotO PF14153.6 EGO55012.1 - 4.6 7.1 10.6 1.8 8.5 7.4 2.0 2 0 0 2 2 2 0 Spore coat protein CotO DUF1769 PF08588.10 EGO55013.1 - 7.3e-28 96.5 0.4 1.8e-27 95.3 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) MPS-4 PF17523.2 EGO55014.1 - 0.85 9.8 3.1 1.5 9.0 3.1 1.3 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 ORC6 PF05460.13 EGO55015.1 - 3.1 7.0 7.9 3.6 6.8 7.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SnoaL_4 PF13577.6 EGO55016.1 - 1.4e-28 99.6 0.3 1.9e-28 99.1 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain Bap31_Bap29_C PF18035.1 EGO55016.1 - 0.16 12.0 0.7 0.24 11.4 0.7 1.3 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain FMO-like PF00743.19 EGO55017.1 - 1.4e-19 70.0 0.0 8.4e-09 34.4 0.0 3.4 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGO55017.1 - 2e-09 37.1 0.8 3.7e-07 29.7 0.0 3.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO55017.1 - 6.1e-08 32.2 0.5 0.011 15.0 0.0 3.4 4 0 0 4 4 4 3 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EGO55017.1 - 4.1e-06 26.2 0.0 0.074 12.3 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO55017.1 - 1.4e-05 25.1 0.1 0.019 15.0 0.0 3.3 4 0 0 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGO55017.1 - 5.6e-05 23.3 0.0 0.00045 20.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO55017.1 - 0.013 15.1 5.1 0.3 10.6 0.3 2.8 2 1 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 EGO55017.1 - 0.051 12.8 0.0 0.37 10.0 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Glu_dehyd_C PF16912.5 EGO55017.1 - 0.071 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Pyr_redox PF00070.27 EGO55017.1 - 0.45 11.1 2.5 5.1 7.7 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 EGO55018.1 - 3.4e-43 147.9 61.2 3.2e-42 144.7 56.4 3.5 2 1 0 2 2 2 1 Major Facilitator Superfamily NDUF_B8 PF05821.11 EGO55020.1 - 3.1e-08 33.7 0.4 3.8e-08 33.4 0.4 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF5473 PF17567.2 EGO55020.1 - 0.096 13.0 0.3 0.18 12.1 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5473) SNF2_N PF00176.23 EGO55021.1 - 4.7e-67 226.2 0.7 1e-65 221.8 0.2 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO55021.1 - 1.1e-18 67.5 0.0 8.1e-18 64.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO55021.1 - 1.7e-10 41.2 0.0 4e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGO55021.1 - 0.0015 18.3 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.13 EGO55021.1 - 0.051 13.9 11.5 0.14 12.5 10.3 2.5 1 1 0 1 1 1 0 HSA HDA2-3 PF11496.8 EGO55021.1 - 0.87 8.7 8.7 1.7 7.7 0.0 4.0 4 1 0 4 4 4 0 Class II histone deacetylase complex subunits 2 and 3 Peptidase_S28 PF05577.12 EGO55023.1 - 1.5e-43 149.3 0.2 1.3e-42 146.1 0.2 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Ank_2 PF12796.7 EGO55026.1 - 6.1e-15 55.6 0.0 1.8e-06 28.4 0.0 3.8 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO55026.1 - 1.3e-08 35.2 0.0 0.011 16.2 0.0 5.5 2 2 4 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 EGO55026.1 - 2e-07 31.2 2.9 0.23 12.0 0.0 5.5 5 1 1 6 6 6 2 Ankyrin repeat Ank_3 PF13606.6 EGO55026.1 - 2.9e-05 24.1 0.3 4.5 8.2 0.0 6.2 7 1 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 EGO55026.1 - 0.00053 20.2 0.2 1.1 9.7 0.0 4.1 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Clr5 PF14420.6 EGO55027.1 - 1.4e-19 70.0 2.5 3.9e-19 68.6 2.5 1.8 1 0 0 1 1 1 1 Clr5 domain SMG1 PF15785.5 EGO55027.1 - 0.065 11.6 0.3 0.089 11.2 0.3 1.1 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 SLAC1 PF03595.17 EGO55030.1 - 3.4e-81 273.0 41.2 3.9e-81 272.8 41.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Tmemb_170 PF10190.9 EGO55030.1 - 0.0033 17.8 1.2 0.0033 17.8 1.2 3.7 3 1 1 4 4 4 1 Putative transmembrane protein 170 Cu-oxidase_3 PF07732.15 EGO55032.1 - 7.6e-40 135.6 4.8 5.9e-38 129.5 0.7 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGO55032.1 - 6.5e-39 132.8 4.7 3.6e-38 130.4 0.1 2.8 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EGO55032.1 - 7.1e-25 88.0 0.0 2.9e-24 86.0 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase GMC_oxred_C PF05199.13 EGO55033.1 - 2.8e-27 96.0 0.0 7.5e-27 94.6 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EGO55033.1 - 1.3e-23 83.8 0.0 3.4e-23 82.5 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EGO55033.1 - 0.0029 16.9 0.0 0.0046 16.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGO55033.1 - 0.0045 16.3 0.0 0.0078 15.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain CBM53 PF16760.5 EGO55033.1 - 0.035 14.7 1.5 0.082 13.5 1.5 1.6 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) FAD_binding_2 PF00890.24 EGO55033.1 - 0.047 12.8 0.0 0.23 10.5 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 EGO55033.1 - 0.084 13.1 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HHH PF00633.23 EGO55033.1 - 0.099 12.6 0.7 3 7.9 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif GatB_N PF02934.15 EGO55034.1 - 6.3e-98 327.5 0.0 8.5e-98 327.1 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EGO55034.1 - 3.4e-09 36.8 0.0 7.8e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 GatB domain Tannase PF07519.11 EGO55035.1 - 2e-92 310.6 0.0 2.5e-92 310.2 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase MFS_1 PF07690.16 EGO55036.1 - 1.9e-29 102.7 23.3 1.9e-29 102.7 23.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_47 PF01532.20 EGO55037.1 - 3.2e-132 441.7 0.0 4.1e-132 441.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Prenyltrans PF00432.21 EGO55039.1 - 0.01 15.5 0.1 0.024 14.4 0.1 1.6 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Coilin_N PF15862.5 EGO55039.1 - 0.015 15.1 12.8 0.051 13.4 0.0 3.2 2 1 1 3 3 3 0 Coilin N-terminus ATG16 PF08614.11 EGO55042.1 - 0.0002 21.7 14.5 0.0002 21.7 14.5 3.5 1 1 3 4 4 4 1 Autophagy protein 16 (ATG16) Bacillus_HBL PF05791.11 EGO55042.1 - 0.0051 16.6 10.4 0.056 13.3 3.8 2.4 1 1 1 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.9 EGO55042.1 - 0.0096 15.9 10.9 0.0096 15.9 10.9 3.3 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.11 EGO55042.1 - 0.01 15.6 21.1 0.055 13.3 5.2 3.4 1 1 2 3 3 3 0 Phage minor structural protein GP20 ZapB PF06005.12 EGO55042.1 - 0.014 15.8 6.1 0.014 15.8 6.1 4.4 2 1 2 4 4 3 0 Cell division protein ZapB Tropomyosin_1 PF12718.7 EGO55042.1 - 0.1 12.7 35.4 0.015 15.5 30.1 2.3 1 1 1 2 2 2 0 Tropomyosin like GAS PF13851.6 EGO55042.1 - 0.2 11.0 31.8 0.024 14.0 16.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.20 EGO55042.1 - 0.39 10.0 35.5 0.98 8.7 32.5 2.1 1 1 1 2 2 2 0 Tropomyosin FPP PF05911.11 EGO55042.1 - 0.95 7.6 32.6 0.16 10.1 4.5 2.9 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil V_ATPase_I PF01496.19 EGO55042.1 - 1 7.2 13.6 1.4 6.7 13.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 EGO55042.1 - 1.1 9.7 41.8 0.024 15.2 8.9 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region HALZ PF02183.18 EGO55042.1 - 1.3 9.3 8.7 36 4.7 0.0 4.4 3 1 0 4 4 4 0 Homeobox associated leucine zipper DivIVA PF05103.13 EGO55042.1 - 1.7 8.7 30.5 0.63 10.1 16.8 3.5 2 1 1 3 3 3 0 DivIVA protein DUF1664 PF07889.12 EGO55042.1 - 2 8.4 13.3 0.21 11.6 0.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EGO55042.1 - 3.3 7.9 22.1 0.21 11.7 3.5 3.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family CorA PF01544.18 EGO55042.1 - 3.3 6.9 15.8 5.1 6.3 12.1 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein KASH_CCD PF14662.6 EGO55042.1 - 4 7.2 36.1 2.3 8.0 9.5 3.1 1 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 EGO55042.1 - 4.4 7.5 33.3 6 7.1 20.1 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Fez1 PF06818.15 EGO55042.1 - 5 7.5 33.1 0.47 10.9 26.2 2.3 1 1 0 2 2 2 0 Fez1 TMF_DNA_bd PF12329.8 EGO55042.1 - 8.8 6.4 28.5 0.41 10.7 5.6 3.9 2 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 EGO55042.1 - 9.3 5.4 19.2 2.7 7.1 9.4 2.2 1 1 1 2 2 2 0 TMPIT-like protein Fungal_trans PF04082.18 EGO55044.1 - 1.5e-22 79.9 0.5 2.3e-22 79.3 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO55044.1 - 1e-07 32.0 11.1 1.6e-07 31.3 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.6 EGO55045.1 - 1.6e-42 145.6 0.0 2.1e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EGO55045.1 - 4.5e-10 39.8 0.0 8.4e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.15 EGO55045.1 - 0.15 11.3 0.0 0.53 9.6 0.0 1.7 2 0 0 2 2 2 0 Beta-galactosidase adh_short_C2 PF13561.6 EGO55046.1 - 3.4e-44 151.1 0.0 1.6e-43 149.0 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO55046.1 - 7.3e-38 130.0 0.0 3.6e-37 127.7 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO55046.1 - 2.2e-07 31.0 0.2 3.8e-07 30.2 0.2 1.4 1 1 0 1 1 1 1 KR domain TFIIA PF03153.13 EGO55047.1 - 1.3 8.9 26.0 1.6 8.6 26.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GET2 PF08690.10 EGO55047.1 - 1.8 8.2 14.9 2.5 7.7 14.9 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 MFS_1 PF07690.16 EGO55050.1 - 3.4e-18 65.7 16.8 5.1e-18 65.1 16.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 EGO55050.1 - 0.023 12.6 0.0 0.033 12.1 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2542 PF10808.8 EGO55050.1 - 0.026 15.0 0.5 0.096 13.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2542) ADH_zinc_N PF00107.26 EGO55051.1 - 1.8e-19 70.0 0.0 2.5e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EGO55051.1 - 2e-19 69.5 0.3 3.3e-18 65.6 0.0 2.4 1 1 1 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EGO55051.1 - 3.6e-07 31.3 0.0 7.5e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 EGO55052.1 - 2.8e-64 216.9 0.8 3.2e-64 216.7 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO55052.1 - 3.3e-42 144.2 0.5 4e-42 143.9 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO55052.1 - 3.9e-14 52.9 0.2 5.8e-14 52.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Ig_GlcNase PF18368.1 EGO55053.1 - 7.3e-36 122.5 0.8 7.3e-36 122.5 0.8 2.2 3 0 0 3 3 3 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 EGO55053.1 - 3.7e-12 46.9 3.0 5.7e-12 46.3 0.6 2.6 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 EGO55053.1 - 0.00038 20.1 0.1 0.0012 18.6 0.1 1.9 1 0 0 1 1 1 1 Ig-fold domain HiaBD2 PF15403.6 EGO55053.1 - 0.11 12.9 0.1 0.37 11.2 0.1 2.0 1 0 0 1 1 1 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) Caleosin PF05042.13 EGO55054.1 - 7.8e-74 247.2 0.1 9.9e-74 246.9 0.1 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 EGO55054.1 - 0.0011 18.7 0.1 4.2 7.6 0.0 3.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 EGO55054.1 - 0.13 11.9 0.7 63 3.5 0.0 3.6 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 EGO55054.1 - 0.19 11.6 0.6 28 4.6 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair HET PF06985.11 EGO55055.1 - 1.6e-22 80.4 0.0 3.9e-18 66.2 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Sde2_N_Ubi PF13019.6 EGO55057.1 - 0.001 18.9 0.1 0.0015 18.4 0.1 1.3 1 1 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain RRM_1 PF00076.22 EGO55059.1 - 1.4e-48 162.5 0.0 4e-14 52.2 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO55059.1 - 1.8e-38 130.3 0.0 3.6e-26 90.8 0.0 4.4 3 1 1 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGO55059.1 - 7.2e-09 35.5 0.0 0.0063 16.5 0.0 3.0 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EGO55059.1 - 2.7e-05 23.7 0.0 1.1 8.9 0.0 4.0 1 1 3 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 EGO55059.1 - 0.00036 20.4 0.0 0.077 13.0 0.0 3.0 3 0 0 3 3 3 1 RL domain RRM_3 PF08777.11 EGO55059.1 - 0.0019 18.2 0.1 0.35 10.9 0.0 3.5 4 0 0 4 4 4 1 RNA binding motif Lsm_interact PF05391.11 EGO55059.1 - 0.004 16.6 1.0 0.0099 15.3 1.0 1.6 1 0 0 1 1 1 1 Lsm interaction motif PHM7_cyt PF14703.6 EGO55059.1 - 0.018 15.3 19.9 29 4.8 9.3 6.8 7 2 2 9 9 9 0 Cytosolic domain of 10TM putative phosphate transporter Borrelia_P83 PF05262.11 EGO55059.1 - 0.065 11.7 5.3 0.11 11.0 5.3 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein RRM_7 PF16367.5 EGO55059.1 - 0.074 13.2 0.0 7.9 6.7 0.0 3.0 2 0 0 2 2 2 0 RNA recognition motif DUF2992 PF11208.8 EGO55059.1 - 0.99 9.6 9.8 1.5 9.0 7.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) MARVEL PF01284.23 EGO55060.1 - 1.3e-09 38.2 14.3 1.9e-09 37.7 14.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain CTP_transf_1 PF01148.20 EGO55060.1 - 0.017 14.9 9.0 0.021 14.6 9.0 1.0 1 0 0 1 1 1 0 Cytidylyltransferase family Bax1-I PF01027.20 EGO55060.1 - 0.04 13.7 11.9 0.05 13.4 11.9 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 YesK PF14150.6 EGO55060.1 - 0.34 11.1 8.1 4 7.7 3.8 2.4 2 1 0 2 2 2 0 YesK-like protein YfhO PF09586.10 EGO55060.1 - 0.66 8.1 11.9 0.79 7.9 11.9 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Tetraspanin PF00335.20 EGO55060.1 - 1.8 8.2 11.8 3.1 7.5 10.0 1.9 1 1 1 2 2 2 0 Tetraspanin family RDD PF06271.12 EGO55060.1 - 2.4 8.4 13.5 1.9e+02 2.2 13.5 2.1 1 1 0 1 1 1 0 RDD family DUF4079 PF13301.6 EGO55060.1 - 2.8 8.1 9.0 32 4.6 9.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF4199 PF13858.6 EGO55060.1 - 5.3 7.4 16.5 5.2 7.4 9.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) FAD_binding_3 PF01494.19 EGO55061.1 - 3.2e-77 260.1 0.0 4.1e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGO55061.1 - 0.0053 16.4 2.3 0.13 11.8 2.2 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO55061.1 - 0.014 14.6 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO55061.1 - 0.032 14.5 2.6 0.1 12.8 2.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGO55061.1 - 0.073 12.1 0.2 0.21 10.6 0.4 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 EGO55061.1 - 0.082 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EGO55061.1 - 0.16 12.5 0.1 1.8 9.1 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGO55061.1 - 0.23 10.5 2.9 0.4 9.7 2.5 1.5 1 1 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EGO55061.1 - 0.29 10.3 0.5 2.8 7.1 0.8 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BNR_2 PF13088.6 EGO55062.1 - 9.8e-14 51.3 1.4 5.7e-09 35.7 1.4 3.3 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 EGO55062.1 - 1.8e-05 24.0 25.3 0.071 13.1 0.7 6.4 6 0 0 6 6 6 4 BNR/Asp-box repeat Mo-co_dimer PF03404.16 EGO55062.1 - 0.00055 20.0 2.3 0.66 10.0 0.0 4.3 4 1 1 5 5 5 1 Mo-co oxidoreductase dimerisation domain DUF4185 PF13810.6 EGO55062.1 - 0.00088 18.6 7.3 0.26 10.5 0.2 4.1 1 1 3 4 4 4 2 Domain of unknown function (DUF4185) BNR_3 PF13859.6 EGO55062.1 - 0.03 13.6 0.0 6.8 5.9 0.0 2.9 2 1 1 3 3 3 0 BNR repeat-like domain CHB_HEX_C PF03174.13 EGO55062.1 - 0.18 11.8 0.1 7.7 6.6 0.0 3.2 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Sortilin-Vps10 PF15902.5 EGO55062.1 - 0.79 8.4 11.8 2.3 6.9 1.7 3.8 3 2 1 4 4 4 0 Sortilin, neurotensin receptor 3, ADH_N PF08240.12 EGO55063.1 - 1.3e-26 92.6 1.4 2.1e-26 91.9 1.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 EGO55063.1 - 8.1e-09 35.3 3.1 4.1e-08 33.0 3.1 2.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 EGO55063.1 - 6.6e-08 32.6 0.0 7.6e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase FANCL_C PF11793.8 EGO55063.1 - 0.12 12.5 1.1 0.22 11.7 1.1 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain SSP160 PF06933.11 EGO55064.1 - 7.9 4.5 11.1 11 4.1 11.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 WHEP-TRS PF00458.20 EGO55066.1 - 0.018 15.2 0.7 0.034 14.3 0.7 1.4 1 0 0 1 1 1 0 WHEP-TRS domain CFEM PF05730.11 EGO55067.1 - 8.3e-12 45.0 12.8 8.3e-12 45.0 12.8 1.3 1 1 0 1 1 1 1 CFEM domain Apolipoprotein PF01442.18 EGO55069.1 - 0.0046 16.8 13.0 0.11 12.4 12.7 2.4 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EGO55069.1 - 0.0077 16.3 14.1 0.038 14.1 3.0 3.4 1 1 2 3 3 3 2 Apolipophorin-III precursor (apoLp-III) CsbD PF05532.12 EGO55069.1 - 0.013 15.4 56.1 8.4 6.4 5.5 7.3 1 1 4 5 5 5 0 CsbD-like YtxH PF12732.7 EGO55069.1 - 0.62 10.6 35.1 18 5.9 4.5 5.0 1 1 1 2 2 2 0 YtxH-like protein LEA_4 PF02987.16 EGO55069.1 - 1.2 9.3 52.4 0.37 10.9 6.9 6.2 5 2 1 6 6 6 0 Late embryogenesis abundant protein ECH_1 PF00378.20 EGO55070.1 - 2.7e-39 135.0 0.0 2e-34 119.1 0.0 3.1 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGO55070.1 - 1.7e-27 96.8 0.0 3.8e-24 85.8 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase HET PF06985.11 EGO55073.1 - 6.9e-21 75.1 0.0 1e-20 74.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ELYS PF13934.6 EGO55074.1 - 8e-66 222.2 0.1 9.5e-66 221.9 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly HUN PF08729.10 EGO55075.1 - 4.6e-08 32.9 0.4 4.6e-08 32.9 0.4 1.8 2 0 0 2 2 2 1 HPC2 and ubinuclein domain RPAP1_C PF08620.10 EGO55076.1 - 6.6e-28 96.6 0.5 1.2e-27 95.8 0.0 1.8 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EGO55076.1 - 3.9e-20 71.4 3.9 7.4e-20 70.5 3.9 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal MFS_1 PF07690.16 EGO55077.1 - 2.2e-33 115.6 37.0 2.9e-33 115.3 35.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PRIMA1 PF16101.5 EGO55077.1 - 0.75 9.8 9.4 2.2 8.3 9.4 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF737 PF05300.11 EGO55077.1 - 4.8 7.5 11.2 1.4 9.2 8.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Dicty_REP PF05086.12 EGO55077.1 - 5.9 4.7 4.3 7.4 4.4 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_hydro_43 PF04616.14 EGO55078.1 - 2.6e-16 59.8 0.6 4e-16 59.2 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Linker_histone PF00538.19 EGO55081.1 - 9.1e-27 93.2 0.0 9.1e-27 93.2 0.0 2.1 2 0 0 2 2 2 1 linker histone H1 and H5 family Gti1_Pac2 PF09729.9 EGO55082.1 - 1.6e-40 139.1 3.2 6.9e-36 124.0 0.2 3.5 2 2 1 3 3 3 2 Gti1/Pac2 family tRNA-synt_2 PF00152.20 EGO55086.1 - 4.1e-81 272.5 0.0 5e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGO55086.1 - 1.6e-07 31.2 0.0 2.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGO55086.1 - 0.013 15.0 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF2263 PF10021.9 EGO55088.1 - 4e-11 43.5 0.0 6.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Herpes_UL1 PF05259.11 EGO55089.1 - 0.02 15.0 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus glycoprotein L Sec23_trunk PF04811.15 EGO55090.1 - 6.1e-52 176.6 0.0 1.2e-51 175.6 0.0 1.5 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGO55090.1 - 3.4e-22 78.2 0.1 6e-22 77.4 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EGO55090.1 - 6.3e-18 65.3 0.0 2.2e-17 63.6 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EGO55090.1 - 2.4e-15 56.3 4.2 4.8e-15 55.3 4.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGO55090.1 - 0.00015 21.6 0.0 0.00036 20.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat DUF3972 PF13118.6 EGO55090.1 - 0.1 13.0 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Spt20 PF12090.8 EGO55090.1 - 3.9 7.0 8.1 6.1 6.4 8.1 1.2 1 0 0 1 1 1 0 Spt20 family Lactamase_B_6 PF16661.5 EGO55091.1 - 9e-64 214.5 0.0 1.9e-63 213.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EGO55091.1 - 6.3e-47 159.9 1.1 1.1e-46 159.2 0.0 2.0 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EGO55091.1 - 1.5e-16 60.6 0.0 4.5e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 EGO55091.1 - 7.8e-16 57.8 0.0 1.6e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EGO55091.1 - 0.0082 16.2 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_hydro_17 PF00332.18 EGO55092.1 - 1.6e-06 28.0 1.9 3.7e-06 26.8 0.5 2.2 1 1 2 3 3 3 1 Glycosyl hydrolases family 17 SR-25 PF10500.9 EGO55092.1 - 0.00061 19.5 2.5 0.0011 18.6 2.5 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 EGO55092.1 - 3.6 7.9 15.5 0.5 10.7 10.8 2.0 2 0 0 2 2 2 0 Early growth response N-terminal domain Aminotran_1_2 PF00155.21 EGO55093.1 - 1.7e-34 119.6 0.0 2.1e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGO55093.1 - 0.00053 18.6 0.0 0.00085 18.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glucan_synthase PF02364.15 EGO55094.1 - 0 1362.0 0.0 0 1361.4 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EGO55094.1 - 9e-43 145.7 0.5 3.3e-42 143.9 0.5 2.0 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SprT-like PF10263.9 EGO55096.1 - 1.7e-32 111.6 0.1 3.6e-32 110.6 0.1 1.6 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 EGO55096.1 - 1.6e-05 24.7 2.7 1.6e-05 24.7 2.7 2.2 2 0 0 2 2 2 1 SprT-like zinc ribbon domain HMG_box PF00505.19 EGO55096.1 - 3.7e-05 24.0 0.9 9.9e-05 22.7 0.9 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO55096.1 - 0.0011 19.5 3.4 0.0045 17.5 3.4 2.0 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.13 EGO55096.1 - 5 7.7 0.0 5 7.7 0.0 4.0 3 1 0 3 3 3 0 YABBY protein Mog1 PF04603.12 EGO55097.1 - 5.6e-40 136.9 0.0 6.6e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein HIT PF01230.23 EGO55098.1 - 6e-22 78.2 0.1 9.5e-22 77.6 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGO55098.1 - 3.3e-11 43.7 0.3 6.6e-11 42.7 0.3 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EGO55098.1 - 2.7e-05 24.0 0.1 3.8e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.20 EGO55099.1 - 1.3e-45 155.0 0.0 2.2e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGO55099.1 - 1.1e-14 54.3 0.1 3.9e-14 52.6 0.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGO55099.1 - 9.6e-10 38.8 0.0 2.8e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DNA_pol_A_exoN PF18305.1 EGO55099.1 - 0.15 12.3 0.4 0.61 10.4 0.1 2.2 2 0 0 2 2 2 0 3' to 5' exonuclease C-terminal domain DASH_Dam1 PF08653.10 EGO55100.1 - 2e-26 91.5 1.8 3.1e-26 90.9 1.8 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF167 PF02594.16 EGO55101.1 - 9.5e-24 83.3 1.2 1.3e-23 82.8 1.2 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Redoxin PF08534.10 EGO55102.1 - 3.5e-29 101.4 0.0 4.2e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin CoA_trans PF01144.23 EGO55103.1 - 3.3e-101 337.2 1.8 5.9e-60 202.4 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase IBR PF01485.21 EGO55105.1 - 4e-22 78.2 46.0 4.2e-12 46.1 6.1 4.5 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EGO55105.1 - 0.00022 21.1 4.1 0.00022 21.1 4.1 4.7 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO55105.1 - 0.00047 20.4 5.9 0.00047 20.4 5.9 4.2 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO55105.1 - 0.003 17.4 4.0 0.003 17.4 4.0 4.9 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO55105.1 - 0.021 14.8 31.5 0.07 13.2 4.2 3.8 3 1 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGO55105.1 - 0.32 11.2 31.5 0.055 13.6 1.6 4.6 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING PAXIP1_C PF15364.6 EGO55105.1 - 0.45 10.8 4.9 1.2 9.5 4.9 1.7 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein zf-RING_4 PF14570.6 EGO55105.1 - 4.7 7.1 37.9 0.8 9.5 9.1 4.0 3 1 1 4 4 4 0 RING/Ubox like zinc-binding domain FHA PF00498.26 EGO55106.1 - 1.6e-14 54.0 0.0 2.7e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGO55106.1 - 0.0076 16.5 0.0 0.28 11.5 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain AAA_16 PF13191.6 EGO55107.1 - 2.1e-05 25.0 0.0 5.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.14 EGO55107.1 - 0.006 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EGO55107.1 - 0.025 14.3 0.2 0.057 13.1 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein AAA_22 PF13401.6 EGO55107.1 - 0.17 12.2 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain HCMV_UL139 PF12507.8 EGO55107.1 - 0.2 12.1 0.5 0.49 10.8 0.5 1.6 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein TPR_MLP1_2 PF07926.12 EGO55108.1 - 0.00019 21.5 1.6 0.033 14.2 0.1 2.3 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein AAA_23 PF13476.6 EGO55108.1 - 0.00051 20.6 0.2 0.00054 20.5 0.2 1.2 1 0 0 1 1 1 1 AAA domain SPX PF03105.19 EGO55108.1 - 0.004 17.1 13.4 0.0051 16.8 13.4 1.1 1 0 0 1 1 1 1 SPX domain RAP1 PF07218.11 EGO55108.1 - 0.011 14.0 14.1 0.014 13.7 14.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAM76 PF16046.5 EGO55108.1 - 0.12 11.7 8.3 0.17 11.2 8.3 1.2 1 0 0 1 1 1 0 FAM76 protein Peptidase_S64 PF08192.11 EGO55108.1 - 0.3 9.5 7.4 0.37 9.2 7.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 CDC45 PF02724.14 EGO55108.1 - 0.58 8.4 10.3 0.7 8.1 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Cep57_CLD PF14073.6 EGO55108.1 - 1 9.3 11.6 0.039 14.0 5.4 1.7 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 DUF5423 PF17461.2 EGO55108.1 - 1.7 7.4 18.2 2.1 7.1 18.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) SMYLE_N PF18615.1 EGO55108.1 - 2 7.9 11.6 2.8 7.4 11.6 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain bZIP_2 PF07716.15 EGO55108.1 - 4.8 7.3 12.4 6.7 6.9 3.2 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Macoilin PF09726.9 EGO55108.1 - 8.1 4.9 26.1 38 2.7 6.3 1.8 1 1 1 2 2 2 0 Macoilin family TFIIF_alpha PF05793.12 EGO55108.1 - 9.2 4.7 22.5 17 3.9 22.5 1.4 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Suppressor_APC PF11414.8 EGO55109.1 - 0.008 16.2 2.1 0.014 15.4 2.1 1.5 1 0 0 1 1 1 1 Adenomatous polyposis coli tumour suppressor protein Spc7 PF08317.11 EGO55109.1 - 0.012 14.5 5.2 0.025 13.5 5.3 1.5 1 1 1 2 2 2 0 Spc7 kinetochore protein YabA PF06156.13 EGO55109.1 - 0.11 13.1 2.5 0.15 12.7 1.3 1.8 1 1 0 1 1 1 0 Initiation control protein YabA Fe-ADH PF00465.19 EGO55109.1 - 0.18 10.6 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase ALMT PF11744.8 EGO55109.1 - 1.6 7.5 3.4 1.8 7.3 3.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4746 PF15928.5 EGO55109.1 - 1.6 8.1 10.0 2.2 7.6 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Tup_N PF08581.10 EGO55109.1 - 2.9 8.2 11.5 0.077 13.3 5.3 1.6 2 0 0 2 2 2 0 Tup N-terminal V_ATPase_I PF01496.19 EGO55109.1 - 6.2 4.6 8.9 7.7 4.3 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.8 EGO55110.1 - 0.033 14.4 1.8 0.053 13.8 1.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Gin PF10764.9 EGO55111.1 - 0.015 15.2 1.1 0.029 14.3 1.1 1.5 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin DUF1476 PF07345.11 EGO55115.1 - 0.0022 18.4 0.0 0.0029 18.0 0.0 1.2 1 0 0 1 1 1 1 ATPase inhibitor subunit zeta TauD PF02668.16 EGO55116.1 - 7.2e-35 121.1 0.2 1.1e-34 120.4 0.2 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EGO55116.1 - 1.5e-06 28.7 0.0 4.6e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 EGO55116.1 - 0.024 13.7 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 CsiD Atg14 PF10186.9 EGO55116.1 - 0.2 10.7 1.7 0.39 9.8 1.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_S10 PF00338.22 EGO55117.1 - 9.8e-28 96.3 0.3 1.2e-27 96.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.16 EGO55118.1 - 3.2e-09 36.3 0.1 6.2e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 CUE domain Nucleoporin_FG PF13634.6 EGO55119.1 - 1.3e-08 35.6 119.2 0.0018 19.1 22.7 6.6 3 1 3 6 6 6 2 Nucleoporin FG repeat region zf-CCCH_4 PF18044.1 EGO55119.1 - 0.00047 19.9 0.9 0.00094 18.9 0.9 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGO55119.1 - 0.00079 19.4 3.8 0.0015 18.5 3.8 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EGO55119.1 - 0.0058 16.5 0.7 0.0058 16.5 0.7 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) p450 PF00067.22 EGO55120.1 - 1.5e-62 211.9 0.0 2e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cwf_Cwc_15 PF04889.12 EGO55121.1 - 0.0022 17.8 8.3 0.0022 17.8 8.3 2.1 1 1 1 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Trypan_PARP PF05887.11 EGO55129.1 - 0.047 13.7 0.3 0.063 13.3 0.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Cep57_CLD_2 PF14197.6 EGO55130.1 - 0.0025 17.9 1.5 0.0053 16.8 1.5 1.5 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.9 EGO55130.1 - 0.011 15.7 0.5 0.016 15.3 0.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ALIX_LYPXL_bnd PF13949.6 EGO55130.1 - 0.022 14.1 0.1 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Med21 PF11221.8 EGO55130.1 - 0.21 11.8 6.3 2.3 8.5 1.7 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex adh_short_C2 PF13561.6 EGO55131.1 - 7.2e-55 186.1 1.4 1e-54 185.6 1.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO55131.1 - 2.5e-47 160.8 1.3 3.6e-47 160.4 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO55131.1 - 1.6e-14 54.2 0.3 8.5e-14 51.9 0.8 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EGO55131.1 - 0.0036 16.8 0.2 0.039 13.4 0.2 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CABS1 PF15367.6 EGO55131.1 - 0.079 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 3HCDH_N PF02737.18 EGO55131.1 - 0.14 12.0 0.3 0.27 11.1 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase_Tyr PF07714.17 EGO55132.1 - 0.00089 18.6 0.0 0.0025 17.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGO55132.1 - 0.015 14.7 0.0 0.25 10.7 0.0 2.5 3 1 0 3 3 3 0 Protein kinase domain zf-C2H2 PF00096.26 EGO55134.1 - 2.3e-09 37.2 18.2 0.0002 21.6 5.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO55134.1 - 2.4e-07 30.8 10.7 0.0039 17.6 2.2 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO55134.1 - 5e-05 23.8 16.7 0.11 13.4 4.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EGO55134.1 - 0.0028 17.4 6.7 0.03 14.1 1.3 2.5 2 0 0 2 2 2 2 zinc-finger C2H2-type DUF1314 PF07013.11 EGO55134.1 - 0.039 13.8 0.0 5.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1314) Phostensin_N PF13916.6 EGO55134.1 - 0.057 13.8 1.9 9.8 6.6 4.7 2.9 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal zf-C2H2_6 PF13912.6 EGO55134.1 - 0.3 11.2 6.0 11 6.1 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger AT_hook PF02178.19 EGO55134.1 - 1.3 9.2 5.2 5.5 7.2 5.2 2.2 1 0 0 1 1 1 0 AT hook motif C1_4 PF07975.12 EGO55134.1 - 6.6 7.0 7.8 16 5.9 7.8 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain zf-MYND PF01753.18 EGO55135.1 - 5.3e-14 52.0 10.4 1.3e-13 50.8 10.4 1.7 1 0 0 1 1 1 1 MYND finger DUF4470 PF14737.6 EGO55135.1 - 3.4e-12 46.4 0.0 1.2e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) zf-C6H2 PF15801.5 EGO55135.1 - 0.0036 17.6 1.0 0.0079 16.5 1.0 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding WSC PF01822.19 EGO55136.1 - 6.2e-18 64.8 9.4 6.2e-18 64.8 9.4 1.7 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 EGO55136.1 - 8.7e-07 28.3 2.4 2.1e-06 27.0 2.4 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Insulin_TMD PF17870.1 EGO55136.1 - 0.00093 19.2 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment TMEM154 PF15102.6 EGO55136.1 - 0.0028 17.6 1.4 0.0054 16.6 1.4 1.4 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.11 EGO55136.1 - 0.0073 16.4 1.8 0.011 15.8 1.8 1.3 1 0 0 1 1 1 1 Podoplanin Trp_oprn_chp PF09534.10 EGO55136.1 - 0.021 14.6 0.9 0.039 13.7 0.9 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4366 PF14283.6 EGO55136.1 - 0.025 14.6 0.5 0.043 13.9 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) EphA2_TM PF14575.6 EGO55136.1 - 0.03 15.2 0.0 0.059 14.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RAP1 PF07218.11 EGO55136.1 - 0.27 9.4 11.3 0.38 9.0 11.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MGC-24 PF05283.11 EGO55136.1 - 0.29 11.6 13.3 0.76 10.2 13.3 1.8 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4718 PF15842.5 EGO55136.1 - 1.4 8.7 5.3 2.3 8.0 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Adeno_PV PF03910.13 EGO55136.1 - 3.3 6.3 7.6 5 5.7 7.6 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV Maf_N PF08383.11 EGO55137.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Maf N-terminal region Toprim_3 PF13362.6 EGO55137.1 - 0.14 12.5 1.0 0.22 11.9 1.0 1.6 1 1 0 1 1 1 0 Toprim domain DUF4672 PF15716.5 EGO55139.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) tRNA-synt_His PF13393.6 EGO55140.1 - 9.9e-40 136.7 0.0 3.7e-39 134.8 0.0 1.8 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EGO55140.1 - 8.4e-12 45.1 0.1 2.6e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.20 EGO55140.1 - 0.1 11.6 0.0 1.2 8.2 0.0 2.1 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) Phage_H_T_join PF05521.11 EGO55141.1 - 0.09 13.3 0.2 0.09 13.3 0.2 1.9 2 0 0 2 2 2 0 Phage head-tail joining protein TUSC2 PF15000.6 EGO55141.1 - 0.77 10.1 2.5 0.51 10.6 0.2 1.8 2 0 0 2 2 2 0 Tumour suppressor candidate 2 Xan_ur_permease PF00860.20 EGO55144.1 - 3.1e-62 210.5 33.6 5.8e-61 206.3 33.6 2.1 1 1 0 1 1 1 1 Permease family zf-C2H2_4 PF13894.6 EGO55145.1 - 9.8e-13 47.8 24.8 0.04 14.8 0.7 6.5 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO55145.1 - 2.3e-09 37.2 27.4 0.042 14.3 1.2 6.7 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-met PF12874.7 EGO55145.1 - 7e-09 35.8 21.0 0.00013 22.3 0.9 5.4 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGO55145.1 - 7.9e-08 32.4 27.4 0.00011 22.3 3.5 5.0 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EGO55145.1 - 3.4e-07 30.4 24.2 0.078 13.4 0.5 6.0 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_2 PF12756.7 EGO55145.1 - 5.9e-05 23.3 21.7 0.051 13.9 1.1 5.3 3 2 3 6 6 6 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EGO55145.1 - 0.0016 18.4 17.3 0.33 11.0 0.1 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf_ZIC PF18366.1 EGO55145.1 - 0.0019 18.2 5.1 1.3 9.2 0.0 4.3 4 1 1 5 5 5 1 Zic proteins zinc finger domain zf-DNA_Pol PF08996.10 EGO55145.1 - 0.042 13.6 0.3 0.042 13.6 0.3 2.4 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-C2H2_aberr PF17017.5 EGO55145.1 - 0.11 12.6 8.3 1.9 8.6 1.9 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger AKAP95 PF04988.12 EGO55145.1 - 0.14 12.3 9.0 1.8 8.7 1.0 3.2 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-Di19 PF05605.12 EGO55145.1 - 0.25 11.7 0.4 0.25 11.7 0.4 4.5 4 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_7 PF02591.15 EGO55145.1 - 0.5 10.6 6.9 21 5.4 0.2 4.0 4 0 0 4 4 4 0 C4-type zinc ribbon domain zf-C2H2_9 PF16293.5 EGO55145.1 - 0.5 10.3 9.0 23 5.0 0.2 4.2 2 2 2 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 EGO55145.1 - 2.2 8.4 19.0 1.9 8.6 1.9 3.8 2 1 1 3 3 3 0 BED zinc finger HypA PF01155.19 EGO55145.1 - 6.8 6.8 14.9 1.8 8.6 2.7 3.8 2 2 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-met PF12874.7 EGO55146.1 - 7.4e-16 58.0 19.5 0.0023 18.3 0.1 6.3 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EGO55146.1 - 8.3e-11 41.7 32.4 0.041 14.3 0.3 7.6 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO55146.1 - 4e-10 39.6 26.7 0.15 13.0 0.4 7.8 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EGO55146.1 - 3.1e-09 37.1 24.7 0.00027 21.2 7.7 5.3 2 2 3 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EGO55146.1 - 1.8e-07 31.3 27.1 9.6e-05 22.6 4.4 6.1 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EGO55146.1 - 4.9e-05 23.2 22.6 0.0059 16.6 0.2 5.4 7 0 0 7 7 7 3 C2H2-type zinc finger zf-Di19 PF05605.12 EGO55146.1 - 0.039 14.3 0.4 0.039 14.3 0.4 5.3 4 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding AKAP95 PF04988.12 EGO55146.1 - 6.7 6.9 12.7 5.3 7.3 0.1 3.5 2 2 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) WD40 PF00400.32 EGO55147.1 - 2.5e-26 91.4 13.7 1.9e-07 31.6 0.1 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO55147.1 - 9.5e-11 41.9 0.1 0.002 18.4 0.1 4.3 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGO55147.1 - 0.016 14.8 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain Ge1_WD40 PF16529.5 EGO55147.1 - 0.31 9.9 2.2 4 6.3 0.4 2.9 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cornichon PF03311.14 EGO55148.1 - 1.2e-49 167.7 11.8 1.3e-49 167.5 11.8 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M24 PF00557.24 EGO55149.1 - 3.4e-49 167.4 0.0 4.2e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EGO55149.1 - 3e-21 75.4 7.4 6.7e-21 74.3 7.4 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EGO55149.1 - 5e-05 23.3 4.4 0.00011 22.2 4.4 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EGO55149.1 - 1.1 9.2 4.4 2.5 8.0 4.4 1.7 1 0 0 1 1 1 0 HIT zinc finger FAD_binding_3 PF01494.19 EGO55150.1 - 5.8e-22 78.4 0.0 1.4e-21 77.1 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO55150.1 - 7.1e-05 22.2 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO55150.1 - 0.00019 21.6 0.1 0.00059 20.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGO55150.1 - 0.00029 21.4 0.0 0.01 16.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO55150.1 - 0.0023 16.7 0.1 0.0035 16.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.10 EGO55150.1 - 0.0028 16.8 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase GIDA PF01134.22 EGO55150.1 - 0.0029 16.7 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 EGO55150.1 - 0.0038 16.9 0.0 0.0084 15.7 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGO55150.1 - 0.0073 15.7 0.2 0.021 14.2 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EGO55150.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EGO55150.1 - 0.019 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EGO55150.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NMT_C PF02799.15 EGO55151.1 - 3e-87 291.5 0.2 4.4e-87 291.0 0.2 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EGO55151.1 - 2.2e-66 222.6 0.0 4e-66 221.8 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Abhydrolase_6 PF12697.7 EGO55151.1 - 1e-08 36.0 0.2 2.1e-08 35.0 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO55151.1 - 3.3e-07 30.2 0.0 0.0027 17.4 0.0 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold Acetyltransf_9 PF13527.7 EGO55151.1 - 4.9e-06 26.6 0.1 1.7e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Hydrolase_4 PF12146.8 EGO55151.1 - 3.1e-05 23.4 0.3 0.031 13.6 0.0 3.0 2 1 0 2 2 2 2 Serine aminopeptidase, S33 CMS1 PF14617.6 EGO55151.1 - 0.0052 16.2 0.9 0.0096 15.3 0.9 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Ribosomal_S25 PF03297.15 EGO55151.1 - 0.021 15.0 1.0 0.045 13.9 1.0 1.5 1 0 0 1 1 1 0 S25 ribosomal protein DDRGK PF09756.9 EGO55151.1 - 0.056 13.0 0.4 0.095 12.3 0.4 1.3 1 0 0 1 1 1 0 DDRGK domain FR47 PF08445.10 EGO55151.1 - 0.096 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_1 PF00583.25 EGO55151.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Tyosinase_C PF18132.1 EGO55151.1 - 0.18 12.5 0.1 0.36 11.5 0.1 1.5 1 0 0 1 1 1 0 Tyosinase C-terminal domain DUF2048 PF09752.9 EGO55151.1 - 0.2 10.7 0.2 0.36 9.9 0.2 1.3 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Abhydrolase_6 PF12697.7 EGO55153.1 - 3.5e-13 50.7 1.4 7.6e-13 49.6 1.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO55153.1 - 3.3e-10 40.0 0.1 5.2e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO55153.1 - 2e-09 37.1 0.0 2.1e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EGO55153.1 - 3.7e-06 26.9 0.3 7.3e-06 26.0 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.13 EGO55153.1 - 0.021 14.6 0.0 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein Lipase_3 PF01764.25 EGO55153.1 - 0.044 13.6 0.1 0.084 12.7 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 EGO55153.1 - 0.072 11.8 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Cutinase PF01083.22 EGO55153.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Cutinase Thioesterase PF00975.20 EGO55153.1 - 0.19 11.8 0.5 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain Mod_r PF07200.13 EGO55154.1 - 0.042 14.0 1.8 0.13 12.4 1.8 1.8 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein CTD PF12815.7 EGO55155.1 - 8.5e-28 96.7 38.8 9.9e-20 70.9 19.5 4.3 3 1 1 4 4 4 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.13 EGO55155.1 - 2.7e-25 88.0 0.1 4.6e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 EGO55155.1 - 1.6e-19 70.7 7.3 1.6e-19 70.7 7.3 2.4 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 EGO55155.1 - 0.0018 18.2 24.3 0.0037 17.1 2.9 5.2 7 0 0 7 7 7 2 KOW motif NusG PF02357.19 EGO55155.1 - 0.007 16.9 0.1 1 9.9 0.0 2.4 2 0 0 2 2 2 1 Transcription termination factor nusG DUF3912 PF13051.6 EGO55155.1 - 0.094 13.0 0.9 0.46 10.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3912) Ribosomal_L9_N PF01281.19 EGO55155.1 - 0.17 11.4 0.1 3.4 7.3 0.0 2.8 2 0 0 2 2 2 0 Ribosomal protein L9, N-terminal domain PPV_E1_N PF00524.18 EGO55155.1 - 9.7 6.6 8.7 0.16 12.4 0.6 2.1 2 0 0 2 2 2 0 E1 Protein, N terminal domain zf-C2H2_3 PF13878.6 EGO55156.1 - 0.5 10.2 2.9 1.6 8.7 0.0 2.9 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO Oxidored_molyb PF00174.19 EGO55157.1 - 1.2e-55 187.7 0.2 2.1e-55 187.0 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGO55157.1 - 1.5e-21 76.9 0.1 4.1e-13 49.5 0.0 2.9 2 1 1 3 3 3 2 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 EGO55157.1 - 3.5e-10 39.9 0.0 6.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Trypan_PARP PF05887.11 EGO55157.1 - 6.4 6.8 8.7 0.52 10.3 0.4 2.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF3506 PF12014.8 EGO55158.1 - 3.5e-56 189.0 0.0 7.9e-56 187.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 EGO55158.1 - 1.9e-09 37.2 0.1 4.6e-09 36.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO55158.1 - 2.2e-07 30.6 0.0 6.1e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGO55158.1 - 0.003 17.4 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 F-box Cupin_2 PF07883.11 EGO55159.1 - 3.7e-08 32.9 0.1 6.3e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EGO55159.1 - 0.0011 18.5 0.0 0.0014 18.2 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EGO55159.1 - 0.0031 17.2 0.0 0.0056 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) NmrA PF05368.13 EGO55162.1 - 3.2e-29 102.1 0.0 6.2e-29 101.2 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO55162.1 - 2.4e-09 37.4 0.0 3.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO55162.1 - 0.00017 21.2 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EGO55162.1 - 0.041 14.3 0.1 0.15 12.5 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Hce2 PF14856.6 EGO55163.1 - 9.8e-20 70.8 0.4 1.2e-19 70.5 0.4 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor HPIH PF13323.6 EGO55163.1 - 0.2 11.5 0.2 0.26 11.1 0.2 1.1 1 0 0 1 1 1 0 N-terminal domain with HPIH motif Hce2 PF14856.6 EGO55164.1 - 3.5e-20 72.2 0.2 4.5e-20 71.9 0.2 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor GST_C PF00043.25 EGO55165.1 - 5.8e-07 29.6 0.0 9.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO55165.1 - 1.6e-06 28.0 0.0 5.5e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO55165.1 - 2.4e-06 27.8 0.0 4.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO55165.1 - 3.4e-06 27.2 0.0 6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGO55165.1 - 0.00021 21.6 0.0 0.00051 20.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO55165.1 - 0.0031 17.8 0.0 0.0056 17.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 EGO55165.1 - 0.072 13.7 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain JAB PF01398.21 EGO55166.1 - 1.6e-15 57.2 0.0 2.7e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 EGO55166.1 - 5.8e-07 29.7 0.1 2e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.6 EGO55166.1 - 0.00014 21.6 0.1 0.00037 20.2 0.0 1.7 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain HARE-HTH PF05066.13 EGO55166.1 - 0.025 15.0 0.0 0.051 14.0 0.0 1.5 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain DUF948 PF06103.11 EGO55166.1 - 0.03 14.6 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ZapB PF06005.12 EGO55166.1 - 0.036 14.5 1.2 0.078 13.4 1.2 1.5 1 0 0 1 1 1 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 EGO55166.1 - 0.14 12.5 3.1 0.084 13.1 1.0 1.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain DegS PF05384.11 EGO55166.1 - 0.18 11.3 4.6 0.33 10.4 4.6 1.3 1 0 0 1 1 1 0 Sensor protein DegS Atg14 PF10186.9 EGO55166.1 - 0.25 10.4 3.5 0.39 9.7 3.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2508 PF10704.9 EGO55166.1 - 0.25 11.5 3.6 19 5.5 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2508) YabA PF06156.13 EGO55166.1 - 0.36 11.5 1.3 0.81 10.4 1.3 1.6 1 0 0 1 1 1 0 Initiation control protein YabA DUF4407 PF14362.6 EGO55166.1 - 0.55 9.5 5.1 0.89 8.8 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA PF00004.29 EGO55168.1 - 1.6e-42 145.1 0.0 2.9e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EGO55168.1 - 2.8e-30 104.1 0.3 1.4e-29 101.8 0.3 2.3 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EGO55168.1 - 1.7e-22 79.2 5.0 5.4e-22 77.6 5.0 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EGO55168.1 - 5.4e-06 26.1 0.0 3.3e-05 23.6 0.0 2.4 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGO55168.1 - 1e-05 25.3 0.0 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGO55168.1 - 1.1e-05 25.9 0.1 0.00016 22.1 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EGO55168.1 - 4.9e-05 23.3 0.0 0.00023 21.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGO55168.1 - 5.1e-05 23.6 0.0 0.012 16.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 EGO55168.1 - 5.2e-05 22.6 0.0 8.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EGO55168.1 - 6.8e-05 22.7 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EGO55168.1 - 0.00014 22.1 0.1 0.0095 16.2 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 EGO55168.1 - 0.00026 21.0 0.0 0.00058 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGO55168.1 - 0.00028 20.2 0.0 0.0024 17.1 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 EGO55168.1 - 0.00073 19.7 0.0 0.004 17.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 EGO55168.1 - 0.00083 19.0 0.9 0.52 9.9 0.1 3.2 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 EGO55168.1 - 0.00096 19.3 0.0 0.0027 17.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO55168.1 - 0.0013 19.2 0.0 0.0038 17.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGO55168.1 - 0.0023 17.7 0.0 0.008 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGO55168.1 - 0.013 15.0 0.0 0.097 12.2 0.0 2.4 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 EGO55168.1 - 0.016 15.6 0.0 0.056 13.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGO55168.1 - 0.026 13.9 0.0 0.086 12.2 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EGO55168.1 - 0.038 13.9 0.0 0.38 10.7 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Torsin PF06309.11 EGO55168.1 - 0.043 13.9 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Torsin Parvo_NS1 PF01057.17 EGO55168.1 - 0.054 12.6 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 EGO55168.1 - 0.07 12.4 0.6 1.6 8.0 0.1 2.8 2 1 1 3 3 3 0 Zeta toxin PhoH PF02562.16 EGO55168.1 - 0.083 12.3 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 EGO55168.1 - 0.11 12.2 0.0 0.42 10.3 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EGO55168.1 - 0.12 12.3 0.0 0.92 9.4 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 EGO55168.1 - 0.35 10.6 2.1 1 9.1 0.1 2.6 2 1 2 4 4 4 0 Cytidylate kinase Nop PF01798.18 EGO55169.1 - 2.1e-81 272.8 0.0 2.1e-81 272.8 0.0 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGO55169.1 - 4.7e-17 62.1 0.0 4.7e-17 62.1 0.0 2.5 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RP-C_C PF11800.8 EGO55169.1 - 0.72 9.9 4.6 1.6 8.8 4.6 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region RNA_polI_A34 PF08208.11 EGO55169.1 - 6 6.9 35.8 9.9 6.2 35.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF913 PF06025.12 EGO55169.1 - 8.4 5.3 10.8 14 4.6 10.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) zf-C2H2_4 PF13894.6 EGO55170.1 - 3.2e-06 27.5 20.3 0.071 14.0 1.7 6.0 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.7 EGO55170.1 - 0.0051 17.2 9.6 0.071 13.5 0.5 4.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type Yippee-Mis18 PF03226.14 EGO55170.1 - 0.16 12.2 0.3 3.2 8.0 0.1 2.5 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF1364 PF07102.12 EGO55170.1 - 0.2 11.5 1.2 14 5.6 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1364) zf-C2H2_3rep PF18868.1 EGO55170.1 - 0.24 12.1 1.5 1.3e+02 3.2 0.1 3.7 3 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats NmrA PF05368.13 EGO55171.1 - 1.6e-30 106.4 0.0 2e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO55171.1 - 6.5e-21 75.1 0.0 9.7e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO55171.1 - 5.5e-08 32.6 0.0 1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO55171.1 - 0.00021 20.4 0.0 0.00045 19.3 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 EGO55171.1 - 0.025 15.2 0.0 0.075 13.6 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 EGO55171.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 EGO55171.1 - 0.17 12.4 2.8 0.33 11.4 0.5 2.6 2 2 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ABC_tran PF00005.27 EGO55172.1 - 5.4e-27 95.0 0.0 1.3e-26 93.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 EGO55172.1 - 1.1e-13 51.2 4.9 1.7e-13 50.5 4.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 EGO55172.1 - 4.5e-05 23.4 0.3 8.1e-05 22.6 0.3 1.3 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EGO55172.1 - 0.016 15.3 0.0 0.054 13.6 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGO55172.1 - 0.022 14.8 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_29 PF13555.6 EGO55172.1 - 0.029 14.1 1.4 0.063 13.0 1.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 EGO55172.1 - 0.072 12.1 0.3 0.11 11.5 0.3 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_21 PF13304.6 EGO55172.1 - 0.1 12.4 0.1 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EGO55172.1 - 0.11 12.1 0.1 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain Opy2 PF09463.10 EGO55172.1 - 0.18 12.1 1.1 0.56 10.6 1.1 1.8 1 0 0 1 1 1 0 Opy2 protein ABC2_membrane_3 PF12698.7 EGO55172.1 - 0.25 10.4 6.5 0.43 9.6 6.5 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Roc PF08477.13 EGO55172.1 - 0.31 11.3 1.0 12 6.1 0.1 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TILa PF12714.7 EGO55172.1 - 3.2 7.8 9.3 1.3 9.0 2.3 2.7 2 0 0 2 2 2 0 TILa domain CorA PF01544.18 EGO55173.1 - 0.033 13.5 0.3 0.033 13.5 0.3 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein zf-GRF PF06839.12 EGO55174.1 - 0.039 14.0 3.6 0.088 12.9 3.6 1.6 1 0 0 1 1 1 0 GRF zinc finger EF-hand_1 PF00036.32 EGO55175.1 - 1.6e-35 118.0 13.7 4.9e-09 35.1 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGO55175.1 - 8.4e-33 112.7 5.5 6.8e-16 58.5 0.9 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGO55175.1 - 1.3e-29 99.5 8.7 5.7e-09 35.2 0.0 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGO55175.1 - 2e-25 88.4 6.1 4e-12 45.8 0.1 3.6 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EGO55175.1 - 8.4e-23 78.8 13.2 1.2e-06 27.8 0.0 4.5 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.6 EGO55175.1 - 1.5e-16 60.5 0.4 2.8e-07 30.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGO55175.1 - 1e-09 38.3 3.3 0.00052 19.9 0.2 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGO55175.1 - 1.5e-06 28.5 0.6 0.011 16.1 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EGO55175.1 - 9.6e-06 26.4 0.1 0.011 16.5 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 EGO55175.1 - 0.0003 21.1 0.5 0.77 10.1 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain TerB PF05099.13 EGO55175.1 - 0.00062 19.7 0.5 0.47 10.4 0.0 2.4 2 1 0 2 2 2 2 Tellurite resistance protein TerB Dockerin_1 PF00404.18 EGO55175.1 - 0.00063 19.9 4.5 0.39 10.9 0.7 2.5 2 1 0 2 2 2 2 Dockerin type I domain DUF5580 PF17743.1 EGO55175.1 - 0.009 14.6 0.0 0.057 11.9 0.0 1.8 1 1 1 2 2 2 1 Family of unknown function (DUF5580) Adenine_glyco PF03352.13 EGO55175.1 - 0.014 15.2 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Methyladenine glycosylase EFhand_Ca_insen PF08726.10 EGO55175.1 - 0.034 14.2 0.1 0.086 12.9 0.1 1.7 1 0 0 1 1 1 0 Ca2+ insensitive EF hand Caleosin PF05042.13 EGO55175.1 - 0.05 13.5 1.1 30 4.5 0.0 3.2 1 1 2 4 4 4 0 Caleosin related protein Peptidase_S8 PF00082.22 EGO55176.1 - 1.6e-33 116.2 6.5 2.2e-33 115.8 6.5 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGO55176.1 - 1.8e-08 34.9 0.0 3.4e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 GCFC PF07842.12 EGO55177.1 - 4.8e-85 285.5 4.3 4.8e-85 285.5 4.3 1.7 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EGO55177.1 - 1.7e-13 50.2 5.2 2.1e-13 49.9 3.1 2.2 2 0 0 2 2 2 1 G-patch domain TIP_N PF12457.8 EGO55177.1 - 1.6e-11 44.5 12.4 1.6e-11 44.5 12.4 3.7 3 1 2 5 5 5 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 EGO55177.1 - 1.9e-06 27.9 2.7 1.9e-06 27.9 2.7 4.0 3 1 1 4 4 4 1 G-patch domain FUSC PF04632.12 EGO55177.1 - 0.036 12.6 1.1 0.061 11.9 1.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nop14 PF04147.12 EGO55177.1 - 0.22 9.7 32.8 0.68 8.1 5.6 2.3 2 0 0 2 2 2 0 Nop14-like family HABP4_PAI-RBP1 PF04774.15 EGO55177.1 - 2.4 9.0 33.0 0.17 12.8 2.5 4.3 4 0 0 4 4 4 0 Hyaluronan / mRNA binding family DNA_pol_phi PF04931.13 EGO55177.1 - 3.9 5.4 19.6 0.54 8.3 14.8 1.9 2 0 0 2 2 2 0 DNA polymerase phi Epimerase PF01370.21 EGO55178.1 - 2e-16 60.2 0.0 2.9e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGO55178.1 - 5.3e-10 39.5 0.1 1.7e-09 37.8 0.1 1.9 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGO55178.1 - 9.2e-10 38.0 0.0 1.9e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGO55178.1 - 7.6e-08 31.8 0.1 9.3e-07 28.3 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EGO55178.1 - 3.1e-05 24.0 0.0 6.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EGO55178.1 - 4.3e-05 23.2 0.1 0.0018 17.9 0.0 2.4 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EGO55178.1 - 0.00028 20.4 0.0 0.00058 19.4 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGO55178.1 - 0.0025 17.0 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EGO55178.1 - 0.018 14.5 0.5 0.37 10.2 0.0 2.6 2 1 0 2 2 2 0 short chain dehydrogenase Herpes_capsid PF06112.11 EGO55178.1 - 0.3 11.2 3.4 0.58 10.2 3.4 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF3388 PF11868.8 EGO55181.1 - 0.055 12.8 0.1 0.083 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) ThiS-like PF14453.6 EGO55182.1 - 0.027 14.5 1.5 0.12 12.4 0.6 2.4 1 1 1 2 2 2 0 ThiS-like ubiquitin DUF2341 PF10102.9 EGO55183.1 - 0.051 14.2 0.9 0.078 13.6 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) Spt20 PF12090.8 EGO55188.1 - 0.043 13.4 4.0 0.056 13.0 4.0 1.2 1 0 0 1 1 1 0 Spt20 family Utp12 PF04003.12 EGO55188.1 - 0.081 13.2 1.0 21 5.5 0.0 3.1 3 0 0 3 3 3 0 Dip2/Utp12 Family Polysacc_deac_1 PF01522.21 EGO55191.1 - 9.7e-29 99.8 0.0 3.1e-28 98.2 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGO55191.1 - 0.00042 19.6 0.0 0.00068 18.9 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 SET PF00856.28 EGO55192.1 - 0.019 15.4 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 SET domain MFS_1 PF07690.16 EGO55193.1 - 9.8e-35 120.1 39.1 1.7e-34 119.3 39.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TMEM169 PF15052.6 EGO55193.1 - 1.3 9.2 6.0 0.33 11.1 0.3 2.8 3 0 0 3 3 3 0 TMEM169 protein family adh_short PF00106.25 EGO55194.1 - 3.2e-17 62.6 0.0 6.5e-12 45.3 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO55194.1 - 3.7e-09 36.5 0.0 5.4e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO55194.1 - 0.0014 18.6 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 KR domain HIP1_clath_bdg PF16515.5 EGO55196.1 - 0.0077 16.8 3.8 0.0077 16.8 3.8 2.7 3 0 0 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 CK2S PF15011.6 EGO55196.1 - 0.011 15.6 2.0 0.011 15.6 2.0 1.7 2 0 0 2 2 2 0 Casein Kinase 2 substrate DUF4635 PF15466.6 EGO55196.1 - 0.019 14.5 6.7 0.1 12.1 2.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) PilJ PF13675.6 EGO55196.1 - 0.022 14.8 3.8 0.062 13.3 0.7 2.6 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term FAM76 PF16046.5 EGO55196.1 - 0.048 13.0 6.0 0.054 12.8 6.0 1.1 1 0 0 1 1 1 0 FAM76 protein CLZ PF16526.5 EGO55196.1 - 0.2 12.1 9.8 2.6 8.4 3.6 2.7 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 EGO55196.1 - 0.5 10.7 5.8 5.2 7.4 0.5 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 F-box-like PF12937.7 EGO55197.1 - 0.064 13.2 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 F-box-like zf-C2H2 PF00096.26 EGO55198.1 - 7.2e-10 38.8 4.6 0.00045 20.5 1.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO55198.1 - 1e-06 28.9 1.0 1e-06 28.9 1.0 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO55198.1 - 2.6e-06 27.8 4.7 0.011 16.5 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EGO55198.1 - 0.0044 17.3 0.2 0.014 15.7 0.2 1.8 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 EGO55198.1 - 0.024 14.6 0.1 0.06 13.4 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EGO55198.1 - 0.034 14.1 0.4 0.062 13.2 0.4 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 EGO55198.1 - 0.15 12.4 0.0 0.86 10.0 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EGO55198.1 - 0.57 10.0 4.2 4.5 7.1 0.1 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type COesterase PF00135.28 EGO55199.1 - 1.7e-82 278.0 0.0 2.2e-82 277.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO55199.1 - 0.00081 19.3 1.0 0.0099 15.8 1.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Endopep_inhib PF16800.5 EGO55199.1 - 0.006 16.5 0.2 0.014 15.3 0.2 1.6 1 0 0 1 1 1 1 IseA DL-endopeptidase inhibitor Peptidase_S9 PF00326.21 EGO55199.1 - 0.0072 15.8 0.1 0.047 13.2 0.6 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2849 PF11011.8 EGO55200.1 - 0.12 13.1 1.7 0.15 12.8 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) Mit_KHE1 PF10173.9 EGO55201.1 - 0.036 14.2 0.2 2.4 8.2 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related P21-Arc PF04062.14 EGO55202.1 - 8.1e-72 240.9 0.0 9.3e-72 240.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.13 EGO55203.1 - 3.5e-122 407.2 0.0 4.4e-122 406.9 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family CDC45 PF02724.14 EGO55203.1 - 0.0023 16.3 0.2 0.003 16.0 0.2 1.2 1 0 0 1 1 1 1 CDC45-like protein MFMR_assoc PF16596.5 EGO55203.1 - 0.013 15.9 1.8 0.013 15.9 1.8 1.7 2 0 0 2 2 2 0 Disordered region downstream of MFMR CPSF100_C PF13299.6 EGO55203.1 - 3 8.0 8.9 0.64 10.2 4.4 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal GST_N_2 PF13409.6 EGO55204.1 - 5.6e-14 52.2 0.0 1e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Fasciclin PF02469.22 EGO55206.1 - 9.5e-19 67.9 2.6 1.6e-18 67.1 0.2 2.4 3 0 0 3 3 3 1 Fasciclin domain Tn7_TnsC_Int PF11426.8 EGO55206.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Tn7 transposition regulator TnsC Inositol_P PF00459.25 EGO55207.1 - 8.8e-29 100.9 0.0 2.5e-28 99.4 0.0 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family CorA PF01544.18 EGO55208.1 - 4.5e-07 29.5 3.0 4.5e-07 29.5 3.0 2.3 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein p450 PF00067.22 EGO55209.1 - 2.5e-32 112.3 0.0 9.7e-32 110.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO55210.1 - 0.00099 18.0 0.0 0.0013 17.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.25 EGO55212.1 - 3.6e-08 33.6 0.0 5.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO55212.1 - 0.00038 20.8 0.0 0.00059 20.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO55212.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein PHO4 PF01384.20 EGO55213.1 - 8.2e-113 376.9 21.3 9.4e-113 376.7 21.3 1.0 1 0 0 1 1 1 1 Phosphate transporter family DIM PF08194.12 EGO55214.1 - 0.25 11.6 1.2 0.4 10.9 1.2 1.3 1 0 0 1 1 1 0 DIM protein Glycos_transf_1 PF00534.20 EGO55215.1 - 9.9e-23 80.5 0.0 2.9e-22 79.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGO55215.1 - 1.3e-14 54.8 0.0 2e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGO55215.1 - 0.011 16.1 0.0 0.034 14.5 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 Thymidylat_synt PF00303.19 EGO55216.1 - 3.5e-107 357.5 0.0 4.2e-107 357.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase AKAP2_C PF15304.6 EGO55216.1 - 0.19 11.0 2.0 0.24 10.7 0.0 2.1 3 0 0 3 3 3 0 A-kinase anchor protein 2 C-terminus NAD_binding_1 PF00175.21 EGO55218.1 - 3.1e-09 37.4 0.0 6.6e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 EGO55218.1 - 3.7e-09 37.1 0.0 5.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 EGO55218.1 - 7.6e-07 29.4 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 EGO55218.1 - 1.5e-06 28.2 0.1 2.4e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 EGO55218.1 - 0.0079 16.3 0.0 0.082 13.0 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain ketoacyl-synt PF00109.26 EGO55220.1 - 1.3e-78 264.1 0.0 2.3e-78 263.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EGO55220.1 - 1.9e-48 164.8 0.1 5.8e-48 163.2 0.0 1.9 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EGO55220.1 - 3.8e-45 154.8 0.1 7.2e-45 153.9 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EGO55220.1 - 1.3e-38 132.9 0.0 2.9e-38 131.8 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EGO55220.1 - 4.7e-30 104.0 0.9 3.6e-29 101.2 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EGO55220.1 - 5.9e-11 42.2 0.0 1.6e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 EGO55220.1 - 7.2e-06 26.4 0.1 3.3e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EGO55220.1 - 8.7e-06 26.0 0.0 2.4e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EGO55220.1 - 0.00049 19.5 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.6 EGO55220.1 - 0.001 18.9 0.0 0.015 15.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO55220.1 - 0.14 12.0 0.0 0.46 10.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Aldose_epim PF01263.20 EGO55221.1 - 2.6e-50 171.4 0.1 3.2e-50 171.1 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Arrestin_N PF00339.29 EGO55221.1 - 0.16 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain OPT PF03169.15 EGO55222.1 - 2.9e-172 574.5 48.2 3.3e-172 574.3 48.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3405 PF11885.8 EGO55223.1 - 2.1e-144 481.9 4.3 2.8e-144 481.6 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DIM1 PF02966.16 EGO55224.1 - 6.2e-68 226.7 0.4 6.9e-68 226.5 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EGO55224.1 - 0.0074 16.3 0.0 0.0096 15.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin EcoEI_R_C PF08463.10 EGO55224.1 - 0.065 13.3 0.0 0.13 12.4 0.0 1.5 2 0 0 2 2 2 0 EcoEI R protein C-terminal Glyco_hydro_18 PF00704.28 EGO55225.1 - 1.7e-10 41.2 0.0 3.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AvrM-A PF18241.1 EGO55225.1 - 3.8 7.9 7.4 5.8 7.3 0.6 2.3 2 0 0 2 2 2 0 Flax-rust effector AvrM-A FAD_binding_3 PF01494.19 EGO55226.1 - 2.4e-13 50.1 1.7 1.1e-06 28.1 0.1 3.3 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 EGO55226.1 - 0.083 13.1 1.6 0.16 12.2 0.6 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO55226.1 - 0.084 12.1 0.1 0.17 11.1 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EGO55227.1 - 1.2e-13 50.4 0.1 9.4e-11 40.8 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGO55227.1 - 2.3e-13 50.1 0.0 3.4e-10 39.6 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO55227.1 - 1.1e-11 44.5 0.0 1.9e-09 37.2 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO55227.1 - 3.2e-09 36.4 0.0 7.3e-07 28.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGO55227.1 - 5.7e-05 23.3 0.0 0.00031 20.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGO55227.1 - 0.00076 18.8 0.0 0.0018 17.6 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EGO55227.1 - 0.01 15.2 0.0 0.024 14.0 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGO55227.1 - 0.014 15.9 0.0 13 6.4 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO55227.1 - 0.027 13.2 0.1 0.13 11.0 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 EGO55227.1 - 0.055 12.5 0.1 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.19 EGO55227.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain VSP PF03302.13 EGO55228.1 - 0.0055 15.6 0.6 0.0081 15.1 0.6 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein K_channel_TID PF07941.11 EGO55228.1 - 0.007 16.8 8.0 0.007 16.8 8.0 2.2 3 0 0 3 3 3 1 Potassium channel Kv1.4 tandem inactivation domain DUF2339 PF10101.9 EGO55228.1 - 0.32 9.5 5.1 0.49 8.9 5.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Dicty_CAR PF05462.11 EGO55229.1 - 5.4e-13 48.8 6.3 5.4e-13 48.8 6.3 2.3 2 1 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 EGO55229.1 - 3.3e-10 40.1 8.2 6.2e-10 39.2 8.2 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 EGO55229.1 - 1e-07 31.6 3.4 1.5e-07 31.1 3.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Glyco_hydro_36 PF17167.4 EGO55232.1 - 6.2e-62 209.6 0.0 1.6e-61 208.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_transf_36 PF06165.11 EGO55232.1 - 6.9e-29 101.0 0.0 1.2e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 36 Glyco_hydro_65C PF03633.15 EGO55232.1 - 0.0048 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Bac_rhamnosid6H PF17389.2 EGO55232.1 - 0.005 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Sigma70_r1_2 PF00140.20 EGO55232.1 - 0.023 14.7 0.4 6.9 6.8 0.1 2.5 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 Reg_prop PF07494.11 EGO55232.1 - 0.13 12.5 0.1 0.45 10.9 0.1 2.0 1 0 0 1 1 1 0 Two component regulator propeller Beta_helix PF13229.6 EGO55233.1 - 2e-10 40.8 12.7 1.2e-09 38.2 12.6 2.2 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EGO55233.1 - 0.013 14.8 5.6 0.073 12.3 3.3 2.4 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) Phospholip_A2_3 PF09056.11 EGO55234.1 - 1e-31 109.8 0.6 1.6e-31 109.2 0.6 1.3 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 MgtE_N PF03448.17 EGO55234.1 - 0.14 12.7 0.4 0.22 12.1 0.4 1.2 1 0 0 1 1 1 0 MgtE intracellular N domain SieB PF14163.6 EGO55234.1 - 0.2 11.2 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B Adeno_E3_CR2 PF02439.15 EGO55235.1 - 0.12 12.1 0.1 0.34 10.7 0.1 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MARVEL PF01284.23 EGO55235.1 - 0.15 12.1 0.1 0.15 12.1 0.1 1.5 2 0 0 2 2 2 0 Membrane-associating domain DUF1627 PF07789.12 EGO55236.1 - 0.19 11.4 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) HSP20 PF00011.21 EGO55237.1 - 1.8e-14 53.7 0.2 1.1e-08 35.1 0.0 2.4 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGO55237.1 - 0.0073 15.8 0.0 2.4 7.8 0.0 2.2 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Paf1 PF03985.13 EGO55237.1 - 0.075 12.0 2.6 0.096 11.7 2.6 1.1 1 0 0 1 1 1 0 Paf1 p450 PF00067.22 EGO55238.1 - 7.9e-70 235.9 0.0 1e-69 235.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ank_4 PF13637.6 EGO55240.1 - 4.8e-05 23.8 0.0 0.33 11.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO55240.1 - 0.0015 18.9 0.0 0.1 13.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EGO55240.1 - 0.0019 18.8 0.0 0.63 10.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) MoeA_N PF03453.17 EGO55241.1 - 1.6e-29 102.7 0.1 3e-29 101.8 0.1 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 EGO55241.1 - 2.1e-23 82.6 0.0 3.6e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 EGO55241.1 - 1.3e-05 25.2 0.0 0.00039 20.5 0.0 2.7 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) zf-A20 PF01754.16 EGO55241.1 - 0.53 10.3 9.6 0.11 12.5 2.8 2.5 2 0 0 2 2 2 0 A20-like zinc finger CBM_1 PF00734.18 EGO55242.1 - 1.6e-09 37.6 7.8 1.6e-09 37.6 7.8 2.8 3 0 0 3 3 3 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.6 EGO55242.1 - 1.8e-07 31.7 0.2 2.6e-07 31.2 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGO55242.1 - 0.0001 22.3 0.0 0.00014 21.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RGS PF00615.19 EGO55244.1 - 3.3e-05 24.1 0.0 0.0034 17.7 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain 2OG-FeII_Oxy_3 PF13640.6 EGO55246.1 - 1.7e-09 38.4 0.2 3.5e-09 37.4 0.2 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 EGO55248.1 - 4.3e-14 52.2 31.5 1.4e-09 37.4 11.1 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4191 PF13829.6 EGO55248.1 - 0.13 11.6 0.0 0.13 11.6 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) Abhydrolase_3 PF07859.13 EGO55249.1 - 6.8e-57 192.7 0.3 8.4e-57 192.4 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO55249.1 - 4.1e-06 26.4 0.0 8.8e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EGO55249.1 - 0.00057 19.5 0.0 0.006 16.2 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family COesterase PF00135.28 EGO55249.1 - 0.0013 17.7 0.0 0.032 13.1 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Hydrolase_4 PF12146.8 EGO55249.1 - 0.0029 16.9 0.1 0.0095 15.2 0.1 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 EGO55249.1 - 0.0056 15.4 0.0 0.0082 14.8 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 EGO55249.1 - 0.024 14.1 0.1 0.048 13.1 0.1 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 EGO55249.1 - 0.13 12.8 8.3 0.15 12.6 7.4 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydro_lipase PF04083.16 EGO55249.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF3336 PF11815.8 EGO55251.1 - 9e-34 116.1 0.1 1.7e-33 115.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EGO55251.1 - 4.2e-20 72.8 0.0 8.2e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Cu_amine_oxid PF01179.20 EGO55253.1 - 6.8e-131 436.9 5.8 8.7e-131 436.6 5.8 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 EGO55253.1 - 1.1e-33 114.7 2.0 1.3e-33 114.5 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1965) FA_hydroxylase PF04116.13 EGO55256.1 - 5.6e-26 91.5 10.7 5.6e-26 91.5 10.7 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily LrgA PF03788.14 EGO55256.1 - 0.87 9.6 4.2 1 9.3 0.1 2.5 3 0 0 3 3 3 0 LrgA family NmrA PF05368.13 EGO55258.1 - 4.7e-34 117.9 0.0 5.8e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO55258.1 - 2.8e-13 50.2 0.0 4e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO55258.1 - 5.7e-05 22.7 0.0 0.00015 21.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO55258.1 - 0.017 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EGO55258.1 - 0.05 13.9 0.0 0.071 13.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Beta-lactamase PF00144.24 EGO55259.1 - 2.4e-39 135.5 0.0 5.8e-39 134.2 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 EGO55259.1 - 0.0047 16.5 0.1 0.63 9.6 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 EGO55259.1 - 0.025 14.0 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Hormone_1 PF00103.20 EGO55260.1 - 0.011 15.4 0.8 0.027 14.2 0.8 1.6 1 0 0 1 1 1 0 Somatotropin hormone family Sporozoite_P67 PF05642.11 EGO55260.1 - 1 7.4 6.0 1.6 6.7 6.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SLX9 PF15341.6 EGO55260.1 - 9 6.7 13.1 1.1 9.6 7.6 2.1 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Lyase_aromatic PF00221.19 EGO55267.1 - 9.3e-154 512.5 4.9 1.2e-153 512.2 4.9 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase PDZ PF00595.24 EGO55267.1 - 0.068 13.5 0.0 12 6.3 0.0 3.0 3 0 0 3 3 3 0 PDZ domain adh_short_C2 PF13561.6 EGO55268.1 - 1.7e-58 198.0 0.4 2.4e-58 197.5 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO55268.1 - 1.2e-48 165.2 1.6 1.6e-48 164.7 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO55268.1 - 7.8e-14 52.0 0.2 1.1e-13 51.4 0.2 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 EGO55268.1 - 0.00092 19.2 0.9 0.13 12.2 0.9 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Polysacc_synt_2 PF02719.15 EGO55268.1 - 0.016 14.3 0.4 0.026 13.7 0.4 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein B12-binding PF02310.19 EGO55268.1 - 0.024 14.7 0.1 0.04 14.0 0.1 1.3 1 0 0 1 1 1 0 B12 binding domain DUF1372 PF07116.11 EGO55268.1 - 0.045 13.9 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1372) Epimerase PF01370.21 EGO55268.1 - 0.11 12.0 0.2 0.29 10.5 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Bac_luciferase PF00296.20 EGO55270.1 - 7.8e-63 212.8 0.0 9.5e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF4100 PF13352.6 EGO55270.1 - 0.0069 16.2 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4100) DUF5014 PF16406.5 EGO55270.1 - 0.075 13.3 0.9 3.5 8.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5014) Acyl-CoA_dh_2 PF08028.11 EGO55271.1 - 6.1e-12 46.0 0.6 1.5e-11 44.7 0.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGO55271.1 - 2.1e-07 31.6 0.0 4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGO55271.1 - 1.2e-05 25.4 0.0 4e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGO55271.1 - 0.002 18.4 3.0 0.002 18.4 0.0 2.4 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain SAPS PF04499.15 EGO55273.1 - 7.6e-191 635.1 0.0 1.7e-190 634.0 0.0 1.6 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein DUF308 PF03729.13 EGO55274.1 - 0.0059 16.9 6.2 0.16 12.3 0.1 2.3 2 0 0 2 2 2 2 Short repeat of unknown function (DUF308) DUF3593 PF12159.8 EGO55274.1 - 0.013 15.5 0.2 0.013 15.5 0.2 2.2 2 1 0 3 3 3 0 Protein of unknown function (DUF3593) TMEM100 PF16311.5 EGO55274.1 - 0.25 10.9 1.4 0.26 10.9 0.2 1.6 2 0 0 2 2 2 0 Transmembrane protein 100 DUF4386 PF14329.6 EGO55274.1 - 0.51 10.2 9.6 0.1 12.4 6.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) Meth_synt_2 PF01717.18 EGO55275.1 - 2.1e-15 56.9 0.0 3.8e-15 56.0 0.0 1.4 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EGO55275.1 - 0.019 14.5 0.0 0.35 10.3 0.0 2.3 3 0 0 3 3 3 0 Cobalamin-independent synthase, N-terminal domain Sugar_tr PF00083.24 EGO55276.1 - 8.7e-118 394.0 31.8 9.9e-118 393.8 31.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO55276.1 - 4.7e-24 85.0 36.8 2e-20 73.1 29.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Bac_rhodopsin PF01036.18 EGO55279.1 - 9.5e-47 159.4 15.3 1.2e-46 159.1 15.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Heliorhodopsin PF18761.1 EGO55279.1 - 0.00014 21.2 4.7 0.00026 20.4 4.6 1.7 1 1 0 1 1 1 1 Heliorhodopsin PalH PF08733.10 EGO55279.1 - 0.58 9.1 5.2 0.3 10.0 3.1 1.5 1 1 1 2 2 2 0 PalH/RIM21 zf-C3HC4 PF00097.25 EGO55283.1 - 5.5e-05 23.0 4.5 0.00011 22.0 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO55283.1 - 0.00056 19.7 6.9 0.00082 19.2 6.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO55283.1 - 0.0027 17.5 3.3 0.0027 17.5 3.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO55283.1 - 0.004 17.5 5.3 0.0049 17.2 4.5 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGO55283.1 - 0.1 12.7 3.8 0.13 12.3 3.1 1.6 1 1 0 1 1 1 0 RING-type zinc-finger DUF4428 PF14471.6 EGO55283.1 - 0.23 11.4 6.8 0.45 10.5 6.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) Ribosomal_L40e PF01020.17 EGO55283.1 - 0.56 10.1 4.1 0.19 11.7 1.5 1.6 1 1 0 1 1 1 0 Ribosomal L40e family Shugoshin_C PF07557.11 EGO55284.1 - 1.4 8.8 7.1 0.17 11.7 0.9 2.6 2 0 0 2 2 2 0 Shugoshin C terminus Adaptin_N PF01602.20 EGO55285.1 - 1.6e-139 465.9 2.4 2.2e-139 465.4 2.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGO55285.1 - 3.6e-64 215.7 3.1 8.6e-62 208.0 0.2 2.7 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGO55285.1 - 2.6e-18 66.2 0.1 1.2e-07 32.1 0.0 5.4 2 2 4 6 6 6 6 HEAT repeats HEAT PF02985.22 EGO55285.1 - 4.9e-11 41.9 5.9 0.023 14.9 0.0 7.0 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 EGO55285.1 - 0.00018 21.9 0.1 1 9.9 0.0 4.8 3 1 1 4 4 4 1 HEAT-like repeat UNC45-central PF11701.8 EGO55285.1 - 0.00019 21.4 0.9 0.032 14.2 0.1 2.8 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central RTP1_C1 PF10363.9 EGO55285.1 - 0.011 15.9 0.8 1.8 8.8 0.0 4.0 2 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 EGO55285.1 - 0.028 14.4 0.0 2.8 8.0 0.0 3.3 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.8 EGO55285.1 - 0.048 13.2 0.1 2.7 7.5 0.0 3.1 2 1 1 3 3 3 0 CLASP N terminal CAAP1 PF15335.6 EGO55285.1 - 0.083 13.5 0.3 0.5 11.0 0.1 2.4 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 Cerato-platanin PF07249.12 EGO55286.1 - 0.00086 19.4 0.1 0.0015 18.6 0.1 1.4 1 0 0 1 1 1 1 Cerato-platanin Asparaginase_2 PF01112.18 EGO55287.1 - 4e-44 150.9 0.8 5.6e-44 150.4 0.8 1.1 1 0 0 1 1 1 1 Asparaginase Cytomega_UL20A PF05984.12 EGO55287.1 - 0.13 12.6 0.2 0.32 11.3 0.2 1.6 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein MatE PF01554.18 EGO55288.1 - 3.3e-09 36.6 12.4 0.001 18.7 3.8 4.1 3 2 1 4 4 4 3 MatE Polysacc_synt_C PF14667.6 EGO55288.1 - 0.011 15.8 0.1 0.011 15.8 0.1 3.8 4 1 0 4 4 4 0 Polysaccharide biosynthesis C-terminal domain Sod_Fe_C PF02777.18 EGO55288.1 - 0.032 14.4 0.2 0.078 13.2 0.2 1.6 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain HNF-1_N PF04814.13 EGO55289.1 - 0.49 11.0 2.6 0.96 10.0 2.6 1.4 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus SDA1 PF05285.12 EGO55289.1 - 1.3 8.4 10.9 1.9 7.8 10.9 1.2 1 0 0 1 1 1 0 SDA1 Glyco_transf_20 PF00982.21 EGO55290.1 - 1.2e-197 657.3 0.0 1.4e-197 657.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 EGO55290.1 - 0.076 12.7 0.2 0.24 11.1 0.1 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain Hva1_TUDOR PF11160.8 EGO55291.1 - 1.8e-12 47.2 1.4 2.3e-12 46.9 1.4 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain VID27 PF08553.10 EGO55294.1 - 5e-193 640.9 0.0 7.5e-193 640.4 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EGO55294.1 - 1.8e-73 246.1 0.2 1.8e-73 246.1 0.2 2.5 2 0 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 EGO55294.1 - 1.3e-43 147.7 0.2 3.5e-43 146.3 0.1 1.8 2 0 0 2 2 2 1 VID27 PH-like domain T4bSS_IcmS PF12608.8 EGO55294.1 - 0.22 11.9 5.2 0.59 10.5 0.3 2.5 2 0 0 2 2 2 0 Type IVb secretion, IcmS, effector-recruitment DNA_pol_phi PF04931.13 EGO55294.1 - 9.5 4.2 8.9 17 3.4 8.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi Prenylcys_lyase PF07156.14 EGO55295.1 - 8.9e-82 275.1 0.0 1.2e-81 274.7 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 EGO55295.1 - 5.4e-14 52.2 0.0 1.9e-13 50.4 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGO55295.1 - 8.8e-11 41.7 0.0 2e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EGO55295.1 - 7.9e-06 25.7 0.2 4.1e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGO55295.1 - 6.2e-05 23.0 0.2 0.00043 20.3 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EGO55295.1 - 0.00026 20.3 0.0 0.0023 17.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO55295.1 - 0.0027 17.0 0.1 0.019 14.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 EGO55295.1 - 0.0034 16.7 0.1 0.29 10.4 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EGO55295.1 - 0.0079 16.7 0.1 1.5 9.4 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGO55295.1 - 0.03 13.4 0.3 0.048 12.7 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 EGO55295.1 - 0.07 12.0 0.1 0.22 10.3 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 EGO55295.1 - 0.084 11.6 0.1 0.2 10.4 0.1 1.6 1 0 0 1 1 1 0 HI0933-like protein MCRA PF06100.11 EGO55295.1 - 0.12 11.1 0.1 0.53 9.0 0.0 1.8 2 0 0 2 2 2 0 MCRA family Cpn60_TCP1 PF00118.24 EGO55296.1 - 6.2e-164 546.2 0.3 7e-164 546.1 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PDCD2_C PF04194.13 EGO55297.1 - 7.8e-47 159.6 9.6 2.9e-45 154.5 0.0 3.6 4 1 0 4 4 4 2 Programmed cell death protein 2, C-terminal putative domain CIAPIN1 PF05093.13 EGO55297.1 - 1.6 9.3 6.2 19 5.8 1.3 3.1 3 0 0 3 3 3 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis CSN8_PSD8_EIF3K PF10075.9 EGO55298.1 - 7.1e-43 146.0 0.0 9.3e-43 145.7 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DNA_ligase_A_M PF01068.21 EGO55299.1 - 6e-50 169.7 0.1 2.1e-47 161.4 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGO55299.1 - 4.4e-29 102.0 0.0 9.1e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGO55299.1 - 2.3e-20 73.0 0.0 1.9e-19 70.1 0.0 2.5 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Aldose_epim PF01263.20 EGO55300.1 - 3e-58 197.5 0.0 4.7e-58 196.9 0.0 1.2 1 1 0 1 1 1 1 Aldose 1-epimerase RTC PF01137.21 EGO55301.1 - 2.5e-07 30.1 0.0 2.5e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase AAL_decarboxy PF03306.13 EGO55302.1 - 3.8e-79 265.1 0.3 4.2e-79 264.9 0.3 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase Glyco_hydr_30_2 PF14587.6 EGO55303.1 - 1.1e-15 58.2 6.2 3.1e-15 56.6 5.4 2.0 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 EGO55303.1 - 8.6e-06 25.2 1.2 1.4e-05 24.5 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 AMP-binding PF00501.28 EGO55304.1 - 4.6e-40 137.5 0.2 1.7e-39 135.6 0.2 1.9 1 1 0 1 1 1 1 AMP-binding enzyme TMF_TATA_bd PF12325.8 EGO55304.1 - 0.058 13.6 0.8 0.15 12.3 0.8 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CCDC85 PF10226.9 EGO55304.1 - 0.23 11.1 0.8 0.5 10.0 0.8 1.5 1 0 0 1 1 1 0 CCDC85 family ATG16 PF08614.11 EGO55304.1 - 0.91 9.7 11.7 0.66 10.2 1.3 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 EGO55304.1 - 1.1 9.3 5.6 0.27 11.3 0.7 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 EGO55304.1 - 1.3 9.6 4.4 3.2 8.3 4.3 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 EGO55304.1 - 1.7 7.5 7.1 1.9 7.3 5.8 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Cpn60_TCP1 PF00118.24 EGO55305.1 - 2.8e-156 521.0 6.1 3.2e-156 520.8 6.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 EGO55305.1 - 0.037 13.3 0.6 0.62 9.2 0.5 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PNTB_4TM PF12769.7 EGO55305.1 - 0.11 13.0 0.2 0.37 11.3 0.0 2.0 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch GNAT_acetyltran PF12746.7 EGO55305.1 - 0.12 12.0 0.2 0.31 10.6 0.2 1.7 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_1 PF00583.25 EGO55306.1 - 3.3e-05 24.1 0.0 4.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EGO55306.1 - 0.0084 16.3 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGO55306.1 - 0.038 14.7 0.0 0.059 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_7N PF13733.6 EGO55306.1 - 0.22 11.2 0.1 0.35 10.5 0.1 1.2 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 CBS PF00571.28 EGO55307.1 - 9e-34 115.7 5.6 4.9e-09 36.5 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 EGO55307.1 - 3.5e-09 36.5 0.0 8.9e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 PB1 domain MYT1 PF08474.11 EGO55308.1 - 0.011 15.7 4.3 0.011 15.7 4.3 2.1 2 0 0 2 2 2 0 Myelin transcription factor 1 Tyrosinase PF00264.20 EGO55309.1 - 1.1e-48 166.4 0.0 1.7e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Ank_2 PF12796.7 EGO55311.1 - 0.029 14.9 0.0 2.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) BORCS7 PF16088.5 EGO55311.1 - 0.039 14.2 0.5 0.11 12.7 0.5 1.8 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 SesA PF17107.5 EGO55311.1 - 0.4 10.9 2.2 0.28 11.4 0.2 1.8 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SCAB-Ig PF16709.5 EGO55312.1 - 0.082 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein Glyco_hydro_18 PF00704.28 EGO55314.1 - 8.7e-89 298.3 0.1 1.1e-88 298.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.23 EGO55315.1 - 1.6e-34 117.5 1.4 2.3e-34 117.0 0.9 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 EGO55315.1 - 9.6e-27 92.9 1.8 9.6e-27 92.9 1.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EGO55315.1 - 2.3e-16 59.4 1.0 4.7e-16 58.4 1.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGO55315.1 - 9.8e-06 25.9 0.6 4.8e-05 23.7 0.2 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGO55315.1 - 0.00049 20.2 0.7 0.0011 19.1 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGO55315.1 - 0.0032 18.0 0.7 0.0045 17.5 0.7 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 EGO55315.1 - 0.0035 17.2 0.1 0.0052 16.7 0.1 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGO55315.1 - 0.0054 17.1 1.2 0.0071 16.7 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EGO55315.1 - 0.014 15.4 1.2 3.7 7.6 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Plexin_cytopl PF08337.12 EGO55315.1 - 0.23 10.1 1.6 7.3 5.1 0.4 2.0 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain Ribosomal_S26e PF01283.19 EGO55316.1 - 3.5e-53 178.6 9.3 4.1e-53 178.4 9.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 EGO55316.1 - 0.018 15.0 0.4 0.054 13.5 0.0 2.0 2 0 0 2 2 2 0 Zinc binding domain DUF1918 PF08940.11 EGO55316.1 - 0.038 13.6 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) DUF4668 PF15701.5 EGO55316.1 - 0.2 11.4 2.1 0.23 11.3 1.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) DUF3767 PF12597.8 EGO55318.1 - 6.8e-18 64.4 2.1 8.5e-18 64.0 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF2681 PF10883.8 EGO55318.1 - 0.03 14.7 3.5 0.041 14.3 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CI-B14_5a PF07347.12 EGO55318.1 - 0.046 13.6 0.1 0.057 13.3 0.1 1.1 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Joubert PF15392.6 EGO55318.1 - 0.18 11.5 5.6 0.19 11.4 5.6 1.1 1 0 0 1 1 1 0 Joubert syndrome-associated DUF1744 PF08490.12 EGO55319.1 - 1.8e-159 530.7 0.0 2.6e-159 530.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EGO55319.1 - 1.9e-82 277.1 0.1 3.1e-82 276.4 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EGO55319.1 - 8.6e-15 54.4 0.2 2.2e-12 46.4 0.2 3.1 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EGO55319.1 - 3.2e-09 36.8 0.2 9.6e-09 35.2 0.2 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EGO55319.1 - 5.9e-06 26.4 0.0 2.1e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 RNase_H superfamily MFS_1 PF07690.16 EGO55320.1 - 1.5e-46 159.0 54.2 1.9e-45 155.3 51.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGO55320.1 - 6.5e-14 51.3 25.7 2e-13 49.6 25.7 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGO55320.1 - 6.1e-08 31.9 11.5 6.1e-08 31.9 11.5 2.7 2 1 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 EGO55320.1 - 0.00037 18.9 2.8 0.00037 18.9 2.8 3.4 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family PI3K_1B_p101 PF10486.9 EGO55320.1 - 3.3 5.4 11.6 6 4.5 11.6 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF1451 PF07295.11 EGO55322.1 - 5.7 7.0 16.5 0.88 9.6 5.2 2.8 2 1 0 2 2 2 0 Zinc-ribbon containing domain PhoU PF01895.19 EGO55322.1 - 7.3 7.1 12.0 0.073 13.5 1.3 3.1 3 2 1 4 4 4 0 PhoU domain DUF3176 PF11374.8 EGO55323.1 - 0.21 11.8 2.5 0.46 10.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) NRIP1_repr_4 PF15690.5 EGO55325.1 - 0.19 11.0 0.1 0.68 9.2 0.0 1.8 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 4 WD40 PF00400.32 EGO55326.1 - 4.2e-28 97.0 10.3 6.2e-06 26.9 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 EGO55326.1 - 1.2e-12 47.5 3.0 1.3e-12 47.4 0.7 2.2 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 EGO55326.1 - 3.2e-08 33.8 0.1 0.32 11.3 0.0 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 EGO55326.1 - 0.00016 21.5 0.0 0.0004 20.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 EGO55326.1 - 0.0072 15.7 0.2 0.42 9.9 0.1 3.1 2 2 0 2 2 2 1 WD40-like domain F-box_4 PF15966.5 EGO55326.1 - 0.055 13.3 0.1 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 F-box FMN_dh PF01070.18 EGO55327.1 - 3.6e-100 335.4 0.3 3.8e-99 332.0 0.3 1.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EGO55327.1 - 2.5e-05 23.5 0.6 4.5e-05 22.6 0.6 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EGO55327.1 - 0.0055 15.9 0.2 0.0088 15.2 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EGO55327.1 - 0.014 14.9 0.3 0.19 11.2 0.1 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein Sugar_tr PF00083.24 EGO55329.1 - 2.8e-126 422.0 24.7 3.2e-126 421.9 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO55329.1 - 4.5e-22 78.5 49.3 9.2e-18 64.3 30.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGO55329.1 - 0.0063 15.0 0.6 0.0063 15.0 0.6 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF998 PF06197.13 EGO55329.1 - 0.069 12.7 16.8 0.043 13.4 5.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF998) CLASP_N PF12348.8 EGO55330.1 - 5e-07 29.5 0.3 3e-05 23.7 0.1 2.6 2 0 0 2 2 2 1 CLASP N terminal Cnd1 PF12717.7 EGO55330.1 - 2.4e-06 27.7 0.1 0.0012 19.0 0.2 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGO55330.1 - 1.8e-05 25.0 4.3 1.2 9.5 0.1 5.5 4 3 2 6 6 6 2 HEAT repeats HEAT PF02985.22 EGO55330.1 - 3.4e-05 23.7 4.6 1.4 9.4 0.3 5.7 6 0 0 6 6 5 1 HEAT repeat Adaptin_N PF01602.20 EGO55330.1 - 0.0011 17.6 0.3 0.91 8.0 0.3 2.7 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 EGO55330.1 - 0.014 15.9 2.0 0.91 10.1 0.0 3.7 4 0 0 4 4 2 0 HEAT-like repeat ADIP PF11559.8 EGO55330.1 - 0.026 14.6 11.0 0.074 13.1 11.0 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PEP-utilisers_N PF05524.13 EGO55330.1 - 0.032 14.4 1.3 4.7 7.4 0.2 3.4 3 0 0 3 3 2 0 PEP-utilising enzyme, N-terminal Vac14_Fab1_bd PF12755.7 EGO55330.1 - 0.036 14.6 0.2 1.3 9.7 0.1 3.3 2 1 2 4 4 3 0 Vacuolar 14 Fab1-binding region Proteasom_PSMB PF10508.9 EGO55330.1 - 0.062 11.8 0.3 0.48 8.9 0.1 2.2 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit TAN PF11640.8 EGO55330.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.2 2 1 0 2 2 1 0 Telomere-length maintenance and DNA damage repair Atg14 PF10186.9 EGO55330.1 - 0.13 11.3 3.9 0.28 10.2 3.9 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HALZ PF02183.18 EGO55330.1 - 0.31 11.3 12.4 2.9 8.2 0.3 3.1 2 1 0 2 2 2 0 Homeobox associated leucine zipper THUMP PF02926.17 EGO55330.1 - 0.34 11.0 1.2 0.89 9.7 0.0 2.3 3 0 0 3 3 2 0 THUMP domain CCDC144C PF14915.6 EGO55330.1 - 0.35 9.9 12.4 0.75 8.8 12.4 1.5 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region SHE3 PF17078.5 EGO55330.1 - 0.37 10.5 11.8 0.8 9.4 11.8 1.5 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Golgin_A5 PF09787.9 EGO55330.1 - 0.98 8.8 8.3 2 7.8 8.3 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Cep57_CLD_2 PF14197.6 EGO55330.1 - 1 9.5 17.5 4.3 7.5 7.0 2.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 TMCO5 PF14992.6 EGO55330.1 - 1.3 8.5 7.4 2.4 7.6 7.4 1.3 1 0 0 1 1 1 0 TMCO5 family DLP_helical PF18709.1 EGO55330.1 - 1.3 8.1 4.4 2.9 7.0 4.4 1.5 1 0 0 1 1 1 0 Dynamin-like helical domain Jnk-SapK_ap_N PF09744.9 EGO55330.1 - 1.6 8.9 13.9 6.5 7.0 13.9 2.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 NYD-SP28_assoc PF14775.6 EGO55330.1 - 2 8.6 5.6 0.75 9.9 1.6 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain Syntaxin PF00804.25 EGO55330.1 - 2.2 7.9 8.3 0.58 9.8 3.2 2.3 2 1 0 2 2 2 0 Syntaxin Phage_GP20 PF06810.11 EGO55330.1 - 2.4 7.9 6.4 6.6 6.5 3.7 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 PRKG1_interact PF15898.5 EGO55330.1 - 2.7 9.0 17.8 0.26 12.2 1.0 3.5 3 1 1 4 4 2 0 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 EGO55330.1 - 2.7 6.8 10.2 6.6 5.5 10.2 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 EGO55330.1 - 9.3 7.0 7.1 3.9e+02 1.8 7.1 2.9 1 1 0 1 1 1 0 Initiation control protein YabA WD40 PF00400.32 EGO55331.1 - 2.1e-54 180.2 14.4 2e-08 34.7 0.9 8.4 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO55331.1 - 2.3e-11 43.8 0.0 0.0024 18.1 0.0 3.8 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO55331.1 - 8.2e-09 34.6 0.3 0.001 17.8 0.1 4.1 4 1 1 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGO55331.1 - 1.2e-05 24.2 0.0 0.028 13.2 0.0 3.1 3 0 0 3 3 3 2 Nup133 N terminal like VID27 PF08553.10 EGO55331.1 - 0.084 11.9 0.0 8.3 5.3 0.0 2.2 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Pox_A_type_inc PF04508.12 EGO55331.1 - 0.18 11.7 0.2 0.38 10.7 0.2 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat bZIP_1 PF00170.21 EGO55331.1 - 0.37 10.9 0.8 0.54 10.4 0.1 1.6 2 0 0 2 2 2 0 bZIP transcription factor Crystall_3 PF08964.10 EGO55332.1 - 4.8e-32 110.0 0.2 1.1e-31 108.8 0.2 1.6 1 0 0 1 1 1 1 Beta/Gamma crystallin Membrane_bind PF14564.6 EGO55332.1 - 9.2e-31 106.5 0.0 1.3e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Membrane binding Thiol_cytolys_C PF17440.2 EGO55332.1 - 0.012 15.8 0.6 0.1 12.8 0.3 2.2 2 1 0 2 2 2 0 Thiol-activated cytolysin beta sandwich domain Metallophos PF00149.28 EGO55333.1 - 5.8e-08 33.5 0.0 2.5e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Condensation PF00668.20 EGO55335.1 - 7.3e-70 235.9 24.5 2.8e-29 102.1 0.0 5.5 5 1 0 5 5 4 4 Condensation domain AMP-binding PF00501.28 EGO55335.1 - 7.6e-29 100.6 7.1 5.6e-17 61.5 0.1 3.5 2 1 1 3 3 3 2 AMP-binding enzyme PP-binding PF00550.25 EGO55335.1 - 9e-27 93.2 0.5 8.6e-09 35.6 0.1 4.9 4 0 0 4 4 4 3 Phosphopantetheine attachment site TFIIA PF03153.13 EGO55335.1 - 2.4e-05 24.5 45.7 2.4e-05 24.5 45.7 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EGO55335.1 - 0.00047 18.6 30.0 0.00075 17.9 30.0 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DDHD PF02862.17 EGO55335.1 - 0.0025 18.0 9.0 0.0025 18.0 9.0 1.8 2 0 0 2 2 1 1 DDHD domain Pex14_N PF04695.13 EGO55335.1 - 0.0044 17.7 30.3 0.0085 16.8 28.6 2.4 2 0 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region EPL1 PF10513.9 EGO55335.1 - 0.019 15.4 17.8 0.046 14.1 17.8 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like Velvet PF11754.8 EGO55335.1 - 0.019 14.9 14.3 0.046 13.7 14.3 1.6 1 0 0 1 1 1 0 Velvet factor SART-1 PF03343.13 EGO55335.1 - 0.021 13.4 17.3 0.031 12.9 17.3 1.1 1 0 0 1 1 1 0 SART-1 family Lin-8 PF03353.15 EGO55335.1 - 0.05 13.2 20.3 0.092 12.3 20.3 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist eIF-3_zeta PF05091.12 EGO55335.1 - 0.069 12.1 27.4 0.14 11.1 27.4 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4407 PF14362.6 EGO55335.1 - 0.14 11.4 18.2 0.25 10.6 18.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zip PF02535.22 EGO55335.1 - 0.23 10.6 4.9 0.38 9.9 4.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 EGO55335.1 - 0.25 9.7 6.0 0.38 9.1 6.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.12 EGO55335.1 - 0.26 11.1 20.4 0.49 10.2 20.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 EGO55335.1 - 0.3 10.5 21.5 0.53 9.7 21.5 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TCP PF03634.13 EGO55335.1 - 0.39 11.3 19.8 1.1 9.8 19.8 1.7 1 0 0 1 1 1 0 TCP family transcription factor PA26 PF04636.13 EGO55335.1 - 0.42 9.5 13.8 0.8 8.6 13.8 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CCSAP PF15748.5 EGO55335.1 - 0.68 10.1 24.4 1.6 8.8 24.4 1.6 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PPL5 PF18168.1 EGO55335.1 - 0.72 9.1 13.5 1.3 8.3 13.5 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Presenilin PF01080.17 EGO55335.1 - 0.74 8.5 27.6 1.3 7.8 27.6 1.2 1 0 0 1 1 1 0 Presenilin MAJIN PF15077.6 EGO55335.1 - 0.84 9.4 12.0 2 8.1 12.0 1.7 1 0 0 1 1 1 0 Membrane-anchored junction protein Otopetrin PF03189.13 EGO55335.1 - 0.97 8.2 8.5 1.6 7.4 8.5 1.2 1 0 0 1 1 1 0 Otopetrin DUF908 PF06012.12 EGO55335.1 - 1.1 8.5 15.6 2.4 7.5 15.6 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF1387 PF07139.11 EGO55335.1 - 1.3 8.7 19.3 2.6 7.7 19.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Endostatin PF06482.11 EGO55335.1 - 1.5 8.2 20.4 3.9 6.8 20.4 1.6 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF913 PF06025.12 EGO55335.1 - 1.6 7.7 13.7 3.2 6.6 13.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GREB1 PF15782.5 EGO55335.1 - 1.6 5.8 21.4 2.4 5.2 21.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AAA_23 PF13476.6 EGO55335.1 - 1.6 9.2 22.8 3.2 8.2 22.8 1.4 1 0 0 1 1 1 0 AAA domain SprA-related PF12118.8 EGO55335.1 - 2 7.5 43.4 5.5 6.0 43.4 1.7 1 0 0 1 1 1 0 SprA-related family DUF4746 PF15928.5 EGO55335.1 - 2 7.7 14.3 4 6.8 14.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CPSF100_C PF13299.6 EGO55335.1 - 2.1 8.5 18.5 7 6.8 18.5 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal NPR3 PF03666.13 EGO55335.1 - 2.3 6.9 20.8 4.1 6.1 20.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CLN3 PF02487.17 EGO55335.1 - 2.7 6.9 16.2 4.7 6.2 16.2 1.2 1 0 0 1 1 1 0 CLN3 protein ORC_WH_C PF18137.1 EGO55335.1 - 2.8 8.0 14.5 9.1 6.4 13.9 2.3 2 0 0 2 2 1 0 Origin recognition complex winged helix C-terminal Hid1 PF12722.7 EGO55335.1 - 2.8 6.0 19.0 4.4 5.3 19.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF3_subunit PF08597.10 EGO55335.1 - 2.9 7.7 20.4 5.8 6.7 20.4 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit MMR1 PF08505.10 EGO55335.1 - 3.2 8.0 26.0 0.17 12.2 19.9 1.9 2 0 0 2 2 1 0 Mitochondrial Myo2 receptor-related protein SLC12 PF03522.15 EGO55335.1 - 3.3 6.6 23.2 5.9 5.8 23.2 1.3 1 0 0 1 1 1 0 Solute carrier family 12 MDM10 PF12519.8 EGO55335.1 - 3.5 6.4 17.2 6 5.6 17.2 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Exonuc_VII_L PF02601.15 EGO55335.1 - 3.8 7.0 21.4 4.1 6.9 18.5 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Serinc PF03348.15 EGO55335.1 - 3.8 6.3 11.9 7.3 5.4 11.9 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) VIR_N PF15912.5 EGO55335.1 - 4.2 6.9 13.0 7.8 6.0 13.0 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Plasmodium_Vir PF05795.11 EGO55335.1 - 4.4 6.6 9.5 7.6 5.8 9.5 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Neur_chan_memb PF02932.16 EGO55335.1 - 5.2 7.0 19.0 13 5.7 19.0 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase_fungal PF17667.1 EGO55335.1 - 7 5.3 10.8 16 4.1 10.8 1.5 1 0 0 1 1 1 0 Fungal protein kinase PPP4R2 PF09184.11 EGO55335.1 - 7.2 6.1 14.1 13 5.3 14.1 1.3 1 0 0 1 1 1 0 PPP4R2 Paramyxo_ncap PF00973.19 EGO55335.1 - 8 5.2 15.4 14 4.5 15.4 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CDC45 PF02724.14 EGO55335.1 - 9.1 4.4 19.7 14 3.8 19.7 1.2 1 0 0 1 1 1 0 CDC45-like protein CCDC53 PF10152.9 EGO55335.1 - 9.8 6.6 27.6 37 4.7 27.6 1.9 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Cu-oxidase_2 PF07731.14 EGO55336.1 - 2.6e-42 143.8 5.9 1.1e-39 135.3 0.3 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGO55336.1 - 2.6e-40 137.1 3.0 2.6e-40 137.1 3.0 2.8 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EGO55336.1 - 3.1e-37 128.2 0.0 6.1e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase MARVEL PF01284.23 EGO55337.1 - 1.2e-09 38.3 3.4 2.4e-09 37.4 3.5 1.4 1 1 0 1 1 1 1 Membrane-associating domain Egh16-like PF11327.8 EGO55338.1 - 3.5e-50 171.0 10.2 3.5e-50 171.0 10.2 1.7 2 0 0 2 2 2 1 Egh16-like virulence factor UbiA PF01040.18 EGO55338.1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 UbiA prenyltransferase family Izumo-Ig PF16706.5 EGO55338.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain SARAF PF06682.12 EGO55339.1 - 0.14 11.7 1.5 0.97 9.0 1.2 2.0 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Diphthamide_syn PF01866.17 EGO55340.1 - 6.9e-84 281.9 0.0 1.1e-83 281.2 0.0 1.4 1 1 0 1 1 1 1 Putative diphthamide synthesis protein MFS_1 PF07690.16 EGO55341.1 - 2.6e-35 122.0 73.4 5e-28 98.0 38.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO55341.1 - 4.6e-10 38.9 36.3 4.3e-06 25.9 13.1 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MTABC_N PF16185.5 EGO55341.1 - 2.7 7.4 8.3 1.7 8.1 3.5 2.2 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region Glyco_transf_15 PF01793.16 EGO55342.1 - 1.4e-64 218.4 6.2 1.1e-63 215.4 6.2 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DZR PF12773.7 EGO55343.1 - 0.053 13.6 0.3 16 5.7 0.0 2.6 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 EGO55343.1 - 0.54 9.7 4.8 6.6 6.3 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain L1R_F9L PF02442.17 EGO55344.1 - 6.7 6.5 13.7 0.075 12.9 4.5 2.2 2 0 0 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses HOOK PF05622.12 EGO55344.1 - 7.6 4.5 66.9 1.5 6.9 18.1 2.8 2 1 0 2 2 2 0 HOOK protein PRKG1_interact PF15898.5 EGO55345.1 - 0.00029 21.7 18.5 0.0055 17.6 0.8 3.5 3 0 0 3 3 3 2 cGMP-dependent protein kinase interacting domain YabA PF06156.13 EGO55345.1 - 0.00058 20.4 16.7 0.0082 16.8 1.1 3.8 3 1 1 4 4 4 1 Initiation control protein YabA CENP-Q PF13094.6 EGO55345.1 - 0.0011 19.2 6.4 0.0011 19.2 6.4 2.7 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit HR1 PF02185.16 EGO55345.1 - 0.0037 17.3 0.7 0.0037 17.3 0.7 3.3 3 1 0 3 3 2 1 Hr1 repeat Snapin_Pallidin PF14712.6 EGO55345.1 - 0.0049 17.3 7.8 0.45 11.0 1.1 3.2 3 0 0 3 3 3 2 Snapin/Pallidin DUF2935 PF11155.8 EGO55345.1 - 0.0061 16.9 0.0 0.43 10.9 0.0 2.6 2 2 0 2 2 2 1 Domain of unknown function (DUF2935) WXG100 PF06013.12 EGO55345.1 - 0.015 15.5 8.2 4 7.7 0.6 4.1 5 0 0 5 5 3 0 Proteins of 100 residues with WXG GAS PF13851.6 EGO55345.1 - 0.019 14.3 19.7 0.032 13.6 0.8 2.7 3 0 0 3 3 2 0 Growth-arrest specific micro-tubule binding YppF PF14178.6 EGO55345.1 - 0.027 14.3 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 1 0 YppF-like protein Atg14 PF10186.9 EGO55345.1 - 0.033 13.3 8.0 0.4 9.7 2.3 2.5 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Halogen_Hydrol PF10112.9 EGO55345.1 - 0.053 13.5 2.8 0.72 9.9 0.3 2.7 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein APG6_N PF17675.1 EGO55345.1 - 0.12 12.9 0.2 0.12 12.9 0.2 3.7 2 1 1 3 3 2 0 Apg6 coiled-coil region Spc7 PF08317.11 EGO55345.1 - 0.12 11.2 24.5 0.12 11.3 0.6 3.4 3 1 1 4 4 4 0 Spc7 kinetochore protein DUF1664 PF07889.12 EGO55345.1 - 0.13 12.3 13.0 0.84 9.7 1.7 3.8 2 2 0 3 3 3 0 Protein of unknown function (DUF1664) Lipase_GDSL_2 PF13472.6 EGO55345.1 - 0.15 12.4 0.5 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family T3SSipB PF16535.5 EGO55345.1 - 0.15 12.5 0.0 0.15 12.5 0.0 2.9 3 1 0 3 3 2 0 Type III cell invasion protein SipB DUF4349 PF14257.6 EGO55345.1 - 0.21 11.0 11.9 0.033 13.6 4.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) TPR_MLP1_2 PF07926.12 EGO55345.1 - 0.23 11.5 27.2 0.23 11.5 0.3 3.7 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.19 EGO55345.1 - 0.53 8.0 26.8 0.018 12.9 4.2 2.4 2 1 0 2 2 2 0 Myosin tail LPP PF04728.13 EGO55345.1 - 0.58 10.6 7.1 15 6.1 0.1 4.0 3 2 0 3 3 3 0 Lipoprotein leucine-zipper DUF4472 PF14739.6 EGO55345.1 - 0.68 10.7 16.8 0.27 12.0 1.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) THP2 PF09432.10 EGO55345.1 - 0.79 9.8 8.5 2.6 8.1 1.1 3.0 3 0 0 3 3 2 0 Tho complex subunit THP2 COG2 PF06148.11 EGO55345.1 - 0.8 9.8 14.1 1 9.5 1.0 4.2 2 2 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Cas_DxTHG PF09455.10 EGO55345.1 - 0.82 9.2 9.3 1.7 8.2 8.9 1.7 1 1 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family TMPIT PF07851.13 EGO55345.1 - 0.9 8.7 7.0 4.7 6.4 0.1 2.5 2 0 0 2 2 2 0 TMPIT-like protein Baculo_PEP_C PF04513.12 EGO55345.1 - 1 9.4 9.8 1.5 8.9 0.6 3.5 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 EGO55345.1 - 1.8 9.0 18.2 0.46 10.9 2.1 2.3 2 0 0 2 2 2 0 Fez1 FapA PF03961.13 EGO55345.1 - 2 6.9 19.0 0.13 10.8 6.1 2.7 2 1 1 3 3 3 0 Flagellar Assembly Protein A AATF-Che1 PF13339.6 EGO55345.1 - 2.4 8.9 11.1 1.9 9.2 2.0 2.7 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Occludin_ELL PF07303.13 EGO55345.1 - 3.1 8.6 11.5 2.3 9.0 0.3 3.6 2 2 2 4 4 4 0 Occludin homology domain Sec5 PF15469.6 EGO55345.1 - 3.3 7.5 12.9 4.3 7.1 7.1 3.1 2 1 0 2 2 2 0 Exocyst complex component Sec5 V_ATPase_I PF01496.19 EGO55345.1 - 3.6 5.4 13.8 14 3.4 13.8 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1943 PF09172.11 EGO55345.1 - 4.2 6.5 5.4 0.35 10.1 0.1 1.8 2 1 0 2 2 1 0 Domain of unknown function (DUF1943) DUF724 PF05266.14 EGO55345.1 - 4.7 7.0 18.2 3.3 7.5 1.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Lebercilin PF15619.6 EGO55345.1 - 5.3 6.7 22.6 1.4 8.5 3.4 3.4 2 2 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Laminin_II PF06009.12 EGO55345.1 - 5.3 7.1 14.7 0.43 10.6 1.8 3.6 3 2 0 3 3 3 0 Laminin Domain II Cnn_1N PF07989.11 EGO55345.1 - 5.9 7.1 20.3 1.9 8.7 1.0 4.1 3 1 1 4 4 3 0 Centrosomin N-terminal motif 1 DUF4533 PF15047.6 EGO55345.1 - 6.7 6.2 9.0 0.18 11.3 1.1 2.4 2 2 1 3 3 3 0 Protein of unknown function (DUF4533) DUF4446 PF14584.6 EGO55345.1 - 7.5 6.5 14.2 20 5.2 2.0 4.2 2 2 2 5 5 5 0 Protein of unknown function (DUF4446) IML1 PF12257.8 EGO55346.1 - 0.0023 17.1 0.5 0.0031 16.7 0.5 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 FCD PF07729.12 EGO55346.1 - 0.0056 17.1 2.4 0.013 16.0 2.4 1.6 1 0 0 1 1 1 1 FCD domain TPR_MLP1_2 PF07926.12 EGO55346.1 - 0.15 12.2 21.0 0.032 14.3 9.1 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Cytochrom_B562 PF07361.11 EGO55346.1 - 0.36 11.5 8.8 0.22 12.2 5.0 2.4 3 0 0 3 3 3 0 Cytochrome b562 DUF802 PF05650.11 EGO55346.1 - 8 7.0 7.3 19 5.9 0.1 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF802) MFS_1 PF07690.16 EGO55348.1 - 1.9e-38 132.3 23.8 1.9e-38 132.3 23.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGO55348.1 - 0.00033 20.4 1.9 0.00079 19.2 1.9 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 PRD1_DD PF11087.8 EGO55348.1 - 0.55 10.0 4.5 1.9 8.3 3.1 2.5 1 1 1 2 2 2 0 PRD1 phage membrane DNA delivery Paf1 PF03985.13 EGO55352.1 - 4.4 6.2 13.6 6.4 5.7 13.6 1.2 1 0 0 1 1 1 0 Paf1 SDA1 PF05285.12 EGO55352.1 - 5.8 6.2 22.0 6.2 6.1 22.0 1.1 1 0 0 1 1 1 0 SDA1 FMO-like PF00743.19 EGO55354.1 - 2.7e-11 42.6 0.0 6.2e-11 41.4 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EGO55354.1 - 2e-09 37.0 0.0 3.3e-05 23.2 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGO55354.1 - 4e-07 30.2 0.0 9.1e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGO55354.1 - 0.00014 21.3 0.0 0.0012 18.1 0.0 2.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO55354.1 - 0.00097 18.5 0.0 0.98 8.6 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO55354.1 - 0.033 14.2 0.0 0.29 11.1 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding GBP_PSP PF02425.15 EGO55354.1 - 0.083 12.5 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide Abhydrolase_3 PF07859.13 EGO55355.1 - 2.6e-24 86.3 0.4 3.7e-24 85.8 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO55355.1 - 1.9e-15 56.6 0.0 2.4e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase SPW PF03779.14 EGO55355.1 - 0.11 12.1 0.1 0.48 10.0 0.1 2.0 2 0 0 2 2 2 0 SPW repeat Coatomer_g_Cpla PF16381.5 EGO55356.1 - 0.11 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform TM2 PF05154.16 EGO55357.1 - 0.0032 17.8 1.1 0.0032 17.8 1.1 2.3 2 0 0 2 2 2 1 TM2 domain DnaJ PF00226.31 EGO55358.1 - 1.9e-09 37.5 0.4 1.9e-09 37.5 0.4 1.8 2 0 0 2 2 2 1 DnaJ domain ParD_antitoxin PF03693.14 EGO55358.1 - 0.067 13.6 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH DEAD PF00270.29 EGO55359.1 - 3.4e-44 150.7 0.0 5.1e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO55359.1 - 7.6e-28 97.1 0.5 6.7e-27 94.0 0.3 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO55359.1 - 0.0002 21.4 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGO55359.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit EspF PF04806.12 EGO55361.1 - 0.54 10.7 4.9 0.5 10.8 1.5 2.5 2 0 0 2 2 2 0 EspF protein repeat TMF_DNA_bd PF12329.8 EGO55362.1 - 0.024 14.6 0.8 0.024 14.6 0.8 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding GRP PF07172.11 EGO55362.1 - 6.4 7.5 9.4 2.3 9.0 5.4 2.3 2 0 0 2 2 2 0 Glycine rich protein family zf-C2H2_4 PF13894.6 EGO55363.1 - 8e-08 32.5 2.2 0.0038 17.9 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO55363.1 - 1.2e-06 28.7 3.1 0.0044 17.4 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGO55363.1 - 0.04 13.9 1.6 0.41 10.7 0.5 2.2 1 1 1 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 EGO55363.1 - 0.27 11.6 1.3 6.6 7.1 0.8 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Kinesin PF00225.23 EGO55364.1 - 2.7e-115 384.9 0.0 3.4e-115 384.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGO55364.1 - 2e-26 92.7 0.0 5.1e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Herpes_UL14 PF03580.14 EGO55364.1 - 0.044 14.0 2.3 0.089 13.0 2.3 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Glyco_hydro_115 PF15979.5 EGO55365.1 - 6.7e-138 459.8 1.9 1.1e-137 459.1 1.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 EGO55365.1 - 1.6e-42 145.3 0.0 3e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain TAL_FSA PF00923.19 EGO55367.1 - 1.5e-39 136.1 0.2 1.9e-39 135.7 0.2 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase UbiA PF01040.18 EGO55368.1 - 2.2e-56 190.9 17.7 2.2e-56 190.9 17.7 1.6 1 1 1 2 2 2 1 UbiA prenyltransferase family Myb_DNA-bind_6 PF13921.6 EGO55369.1 - 3.7e-06 27.1 0.4 1.7e-05 24.9 0.1 2.1 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGO55369.1 - 6e-06 26.4 1.2 3.5e-05 23.9 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 EGO55369.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Sugar_tr PF00083.24 EGO55371.1 - 6.8e-120 401.0 23.6 2.2e-119 399.3 23.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO55371.1 - 2.4e-28 99.1 54.8 7.4e-25 87.6 29.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EGO55372.1 - 1.6e-29 103.0 0.0 2.1e-21 76.2 0.5 3.0 1 1 1 2 2 2 2 Cytochrome P450 Epimerase PF01370.21 EGO55373.1 - 6.4e-13 48.7 0.0 1.9e-12 47.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO55373.1 - 2.3e-06 27.3 1.0 8.7e-05 22.1 0.2 3.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGO55373.1 - 0.0034 16.6 1.4 1.2 8.2 0.2 2.9 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EGO55373.1 - 0.0047 16.1 0.1 0.037 13.2 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 EGO55373.1 - 0.092 11.8 0.0 13 4.8 0.0 2.4 2 0 0 2 2 2 0 RmlD substrate binding domain DUF5633 PF18656.1 EGO55374.1 - 0.097 12.6 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5633) Ank_2 PF12796.7 EGO55375.1 - 2.8e-21 75.9 2.7 1.8e-11 44.4 2.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGO55375.1 - 4.4e-17 61.9 4.7 6.5e-06 26.3 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO55375.1 - 1.1e-15 56.2 5.3 0.00045 20.5 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EGO55375.1 - 1.7e-15 57.1 8.5 3.5e-07 30.6 0.2 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EGO55375.1 - 1.5e-13 50.5 9.2 3.7e-05 24.0 0.2 4.5 5 0 0 5 5 5 3 Ankyrin repeat MFS_1 PF07690.16 EGO55378.1 - 2.5e-19 69.4 46.8 1.5e-17 63.6 46.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO55378.1 - 1.2e-07 30.6 23.3 1.5e-07 30.2 23.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4407 PF14362.6 EGO55378.1 - 0.06 12.7 0.7 3.4 7.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF29 PF01724.16 EGO55379.1 - 0.1 12.9 0.4 0.8 9.9 0.1 2.5 3 1 1 4 4 4 0 Domain of unknown function DUF29 zf-CCHC_2 PF13696.6 EGO55379.1 - 0.56 10.1 2.5 1.1 9.1 1.0 2.3 1 1 1 2 2 2 0 Zinc knuckle Polysacc_deac_1 PF01522.21 EGO55381.1 - 1.9e-11 44.0 0.1 3.1e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF1772 PF08592.11 EGO55381.1 - 4.8e-07 30.2 2.8 5.2e-07 30.1 1.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2334 PF10096.9 EGO55381.1 - 0.0087 15.7 0.1 0.032 13.9 0.1 1.9 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) SET PF00856.28 EGO55382.1 - 9.7e-11 42.3 0.0 1.6e-10 41.7 0.0 1.6 1 1 0 1 1 1 1 SET domain PUF PF00806.19 EGO55383.1 - 5.4e-17 60.4 0.0 0.095 12.4 0.0 6.6 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat MRNIP PF15749.5 EGO55383.1 - 0.023 15.4 0.9 0.023 15.4 0.9 3.8 4 0 0 4 4 4 0 MRN-interacting protein UPF0515 PF15135.6 EGO55383.1 - 0.11 11.8 0.2 0.43 9.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 Cob_adeno_trans PF01923.18 EGO55383.1 - 0.73 10.0 4.5 0.69 10.0 0.4 2.9 2 1 0 2 2 2 0 Cobalamin adenosyltransferase T2SSC PF11356.8 EGO55383.1 - 1.2 9.1 3.9 0.59 10.0 0.3 2.4 2 0 0 2 2 2 0 Type II secretion system protein C Phage_holin_3_6 PF07332.11 EGO55384.1 - 0.27 11.3 1.4 1.8 8.7 0.5 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SOG2 PF10428.9 EGO55384.1 - 5.8 6.0 14.4 8.2 5.5 14.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF202 PF02656.15 EGO55385.1 - 0.06 13.8 0.2 0.1 13.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) PhoR PF11808.8 EGO55385.1 - 0.17 12.3 0.1 0.3 11.5 0.1 1.3 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR AMMECR1 PF01871.17 EGO55388.1 - 2.1e-45 154.3 0.0 3.1e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 Sporozoite_P67 PF05642.11 EGO55388.1 - 0.28 9.2 8.8 0.35 8.9 8.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NUDE_C PF04880.13 EGO55388.1 - 1.7 9.1 7.7 2.9 8.3 7.7 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region FSA_C PF10479.9 EGO55388.1 - 5.7 4.9 6.4 7.2 4.6 6.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Pyridoxal_deC PF00282.19 EGO55389.1 - 1.3e-73 247.9 0.0 2.5e-62 210.7 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGO55389.1 - 0.00055 19.0 0.0 0.00083 18.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGO55389.1 - 0.0028 17.0 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Ras PF00071.22 EGO55391.1 - 9.6e-39 132.6 0.0 5e-25 88.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGO55391.1 - 1.8e-11 44.3 0.1 3.8e-11 43.3 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGO55391.1 - 0.0058 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EGO55391.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.4 2 0 0 2 2 2 0 ADP-ribosylation factor family PRK PF00485.18 EGO55391.1 - 0.19 11.4 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Thi4 PF01946.17 EGO55392.1 - 3.9e-111 369.9 0.2 4.9e-111 369.6 0.2 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EGO55392.1 - 6.2e-08 32.6 0.6 9.7e-07 28.7 0.3 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO55392.1 - 1.7e-05 25.0 0.3 5.3e-05 23.4 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO55392.1 - 0.00041 19.7 0.1 0.001 18.4 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGO55392.1 - 0.0011 18.2 0.7 0.0018 17.4 0.6 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EGO55392.1 - 0.0017 18.4 0.3 0.0049 16.9 0.1 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EGO55392.1 - 0.017 14.2 1.4 0.041 13.0 0.5 1.9 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 EGO55392.1 - 0.021 14.2 0.2 0.039 13.3 0.2 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Mqo PF06039.15 EGO55392.1 - 0.024 13.2 0.1 0.056 12.0 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 EGO55392.1 - 0.033 14.7 0.8 0.082 13.5 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO55392.1 - 0.039 13.2 0.2 0.064 12.5 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGO55392.1 - 0.047 12.9 0.1 0.076 12.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EGO55392.1 - 0.11 11.2 0.7 0.18 10.5 0.3 1.5 2 0 0 2 2 2 0 HI0933-like protein NIF3 PF01784.18 EGO55394.1 - 5.6e-65 219.4 0.0 7.1e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.18 EGO55395.1 - 5.6e-20 71.4 0.0 1.4e-19 70.1 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein VHS PF00790.19 EGO55397.1 - 3.5e-44 150.1 0.0 1.3e-43 148.2 0.0 1.9 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 EGO55397.1 - 1.3e-21 77.0 0.1 1.3e-21 77.0 0.1 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.14 EGO55397.1 - 2.6e-19 69.3 1.0 6.8e-19 68.0 0.1 2.2 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 EGO55397.1 - 2.1e-08 33.7 0.0 6.2e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 GGA N-GAT domain AP3B1_C PF14796.6 EGO55397.1 - 0.015 15.5 0.9 0.056 13.7 0.1 2.3 2 1 0 2 2 2 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Ribo_biogen_C PF04034.13 EGO55398.1 - 2.5e-49 166.2 0.1 3.4e-49 165.8 0.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EGO55398.1 - 3.7e-12 45.8 0.7 3.7e-12 45.8 0.7 1.6 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI BUD22 PF09073.10 EGO55398.1 - 0.045 13.1 22.8 0.068 12.5 22.8 1.2 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 EGO55398.1 - 8.5 5.0 11.6 12 4.6 11.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GTP_EFTU PF00009.27 EGO55399.1 - 4.7e-34 117.6 5.4 1.7e-32 112.6 5.4 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGO55399.1 - 1.3e-25 89.6 0.0 2.8e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EGO55399.1 - 1.8e-10 40.9 0.1 3.6e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO55399.1 - 2e-06 27.8 2.5 7.4e-05 22.7 0.2 2.4 1 1 1 2 2 2 1 RsgA GTPase IF2_N PF04760.15 EGO55399.1 - 1.1e-05 25.1 0.0 2.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region FeoB_N PF02421.18 EGO55399.1 - 1.3e-05 24.8 0.3 3.2e-05 23.5 0.3 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU_D2 PF03144.25 EGO55399.1 - 0.00014 22.2 11.5 0.043 14.2 0.1 3.9 2 1 1 3 3 3 2 Elongation factor Tu domain 2 Arf PF00025.21 EGO55399.1 - 0.00015 21.3 0.0 0.00029 20.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EGO55399.1 - 0.00063 19.5 0.2 0.0016 18.2 0.2 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EGO55399.1 - 0.003 17.0 0.1 0.0065 15.9 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EGO55399.1 - 0.0047 17.1 0.0 0.0091 16.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 EGO55399.1 - 0.011 15.7 0.3 0.032 14.2 0.3 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF3987 PF13148.6 EGO55399.1 - 0.021 13.8 3.9 0.064 12.3 3.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Dynamin_N PF00350.23 EGO55399.1 - 0.026 14.6 0.3 8.6 6.4 0.1 3.3 2 1 1 3 3 3 0 Dynamin family MeaB PF03308.16 EGO55399.1 - 0.029 13.4 1.1 0.055 12.4 1.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU_D4 PF14578.6 EGO55399.1 - 0.11 12.4 3.9 0.16 11.9 1.3 2.4 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Top6b_C PF18000.1 EGO55400.1 - 0.27 11.4 0.5 0.6 10.3 0.1 1.7 2 0 0 2 2 2 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain eIF2A PF08662.11 EGO55401.1 - 3.3e-78 262.0 0.0 7.1e-78 260.9 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EGO55401.1 - 0.00014 22.5 0.8 4 8.5 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat CP2 PF04516.15 EGO55404.1 - 4.1e-81 271.6 0.0 6.5e-81 271.0 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Oxysterol_BP PF01237.18 EGO55406.1 - 1.9e-51 175.1 0.0 2.4e-49 168.2 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein GPP34 PF05719.11 EGO55407.1 - 5.3e-68 229.1 0.2 6.6e-68 228.7 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PDH PF02153.17 EGO55407.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase SURF6 PF04935.12 EGO55408.1 - 1.3e-48 165.5 48.4 1.3e-48 165.5 48.4 3.6 2 1 0 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 EGO55408.1 - 5e-19 68.7 1.4 5e-19 68.7 1.4 7.5 5 2 3 8 8 8 1 60S ribosome biogenesis protein Rrp14 XPG_N PF00752.17 EGO55409.1 - 5.9e-23 81.3 0.0 1.1e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGO55409.1 - 2.4e-22 79.1 0.0 5.4e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EGO55409.1 - 0.00082 18.9 0.0 0.0018 17.8 0.0 1.6 2 0 0 2 2 2 1 XPG domain containing Tma16 PF11176.8 EGO55410.1 - 6.2e-46 155.9 7.5 7.4e-46 155.6 7.5 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 CHASE7 PF17151.4 EGO55410.1 - 0.072 12.7 0.4 0.091 12.3 0.4 1.3 1 0 0 1 1 1 0 Periplasmic sensor domain DUF4748 PF15932.5 EGO55410.1 - 6.7 6.5 6.3 2.6 7.9 2.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4748) MAM33 PF02330.16 EGO55413.1 - 2.6e-75 253.0 0.0 3.1e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein LCCL PF03815.19 EGO55414.1 - 1.4e-17 63.6 0.0 3.4e-17 62.3 0.0 1.6 1 1 0 1 1 1 1 LCCL domain Vps51 PF08700.11 EGO55415.1 - 1.3e-31 108.5 0.2 2.9e-31 107.4 0.2 1.6 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 EGO55415.1 - 0.00021 20.1 1.7 0.00029 19.6 1.7 1.2 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.9 EGO55415.1 - 0.0075 16.4 0.1 0.017 15.3 0.1 1.7 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DUF4192 PF13830.6 EGO55415.1 - 0.51 10.4 8.9 0.092 12.8 5.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) ADH_N PF08240.12 EGO55419.1 - 7.2e-07 29.1 0.0 3e-06 27.1 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EGO55419.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase SOG2 PF10428.9 EGO55420.1 - 0.61 9.2 4.0 0.71 9.0 4.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Dicty_REP PF05086.12 EGO55420.1 - 1.2 7.1 3.0 1.6 6.6 3.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NOA36 PF06524.12 EGO55420.1 - 7.8 5.7 11.2 13 5.0 11.2 1.3 1 0 0 1 1 1 0 NOA36 protein BAF1_ABF1 PF04684.13 EGO55420.1 - 8.2 5.4 19.0 12 4.8 19.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MFS_1 PF07690.16 EGO55423.1 - 4.4e-47 160.7 31.6 4.4e-47 160.7 31.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO55423.1 - 2.4e-11 43.2 2.4 2.4e-11 43.2 2.4 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 EGO55423.1 - 2.3e-08 33.7 6.3 2.3e-08 33.7 6.3 2.3 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EGO55423.1 - 0.051 11.9 11.4 0.12 10.7 4.1 3.2 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DUF1748 PF08520.10 EGO55424.1 - 1.6e-33 114.4 0.1 1.8e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.21 EGO55425.1 - 3.3e-169 562.3 5.9 4.4e-169 561.9 5.9 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGO55425.1 - 2.8e-34 117.8 0.0 9.5e-34 116.1 0.0 2.0 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EGO55425.1 - 0.00037 19.7 1.8 0.0013 18.0 0.8 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EGO55425.1 - 0.043 12.8 0.0 0.37 9.7 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Importin_rep_3 PF18806.1 EGO55425.1 - 0.08 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Importin 13 repeat SOAR PF16533.5 EGO55427.1 - 0.062 13.3 0.2 0.062 13.3 0.2 2.2 2 0 0 2 2 2 0 STIM1 Orai1-activating region XTBD PF11952.8 EGO55427.1 - 0.13 12.0 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD DUF4140 PF13600.6 EGO55427.1 - 2.3 8.7 9.1 12 6.4 3.0 3.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3446 PF11928.8 EGO55427.1 - 4.2 7.7 8.1 3.2 8.1 0.5 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain Spc7 PF08317.11 EGO55427.1 - 5.9 5.7 11.4 2.7 6.8 2.4 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Clr5 PF14420.6 EGO55428.1 - 4.7e-19 68.3 0.6 1.1e-18 67.2 0.6 1.5 1 0 0 1 1 1 1 Clr5 domain ApbA PF02558.16 EGO55429.1 - 7.5e-32 110.1 0.0 1e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EGO55429.1 - 2.9e-27 95.4 0.0 4.8e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal MtaB PF12176.8 EGO55429.1 - 0.0051 15.7 0.1 0.0078 15.1 0.1 1.2 1 0 0 1 1 1 1 Methanol-cobalamin methyltransferase B subunit PglD_N PF17836.1 EGO55429.1 - 0.0052 17.4 0.0 0.016 15.8 0.0 1.8 2 0 0 2 2 2 1 PglD N-terminal domain ThiF PF00899.21 EGO55429.1 - 0.29 10.5 0.6 0.53 9.6 0.6 1.4 1 0 0 1 1 1 0 ThiF family DUF4454 PF14628.6 EGO55431.1 - 0.069 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) Fungal_trans PF04082.18 EGO55432.1 - 1.1e-16 60.7 0.1 2.9e-16 59.3 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Lipase_chap PF03280.14 EGO55432.1 - 0.0081 16.1 0.1 0.028 14.4 0.1 1.8 1 0 0 1 1 1 1 Proteobacterial lipase chaperone protein PH_10 PF15411.6 EGO55433.1 - 2.2e-35 121.6 0.3 4.5e-35 120.6 0.3 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 EGO55433.1 - 2e-32 111.3 0.0 4.4e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 EGO55433.1 - 9.5e-31 107.4 0.3 4.6e-30 105.2 0.1 2.0 2 0 0 2 2 2 1 RhoGEF domain PB1 PF00564.24 EGO55433.1 - 1.5e-07 31.2 0.1 3.8e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 PB1 domain AMP-binding PF00501.28 EGO55436.1 - 5e-98 328.5 0.0 6.2e-98 328.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO55436.1 - 3.4e-13 50.4 0.0 1e-12 48.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_8 PF13523.6 EGO55437.1 - 2.6e-46 156.9 1.1 3.9e-46 156.3 1.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.14 EGO55438.1 - 2.4e-26 92.7 0.0 5.2e-26 91.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO55438.1 - 1.4e-12 48.0 3.5 1.6e-10 41.4 0.1 3.0 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGO55438.1 - 0.00027 20.3 0.0 0.00045 19.6 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EGO55438.1 - 0.00034 20.0 0.0 0.0036 16.6 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGO55438.1 - 0.0017 17.6 0.2 0.49 9.6 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 EGO55438.1 - 0.0095 15.0 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EGO55438.1 - 0.014 15.0 0.2 1.1 8.8 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 EGO55438.1 - 0.016 14.4 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGO55438.1 - 0.046 14.0 0.5 2.5 8.4 0.0 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGO55438.1 - 0.048 12.4 1.1 3.2 6.4 0.2 2.4 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.6 EGO55438.1 - 0.095 12.7 0.2 4.5 7.2 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Delta_lysin PF05372.11 EGO55438.1 - 0.22 10.9 0.1 0.51 9.7 0.1 1.5 1 0 0 1 1 1 0 Delta lysin family zf-RING_7 PF02591.15 EGO55439.1 - 0.00049 20.2 2.2 0.32 11.2 0.3 2.8 2 0 0 2 2 2 2 C4-type zinc ribbon domain UPF0547 PF10571.9 EGO55439.1 - 0.1 12.7 0.2 0.1 12.7 0.2 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zinc_ribbon_15 PF17032.5 EGO55439.1 - 0.6 10.9 5.6 2.4 9.0 5.6 2.1 1 1 1 2 2 2 0 zinc-ribbon family Lar_restr_allev PF14354.6 EGO55439.1 - 0.6 10.5 7.7 0.72 10.3 0.1 3.8 4 0 0 4 4 4 0 Restriction alleviation protein Lar zinc_ribbon_12 PF11331.8 EGO55439.1 - 0.7 9.7 9.6 2.8 7.8 1.8 3.3 1 1 2 3 3 3 0 Probable zinc-ribbon domain DZR PF12773.7 EGO55439.1 - 2.2 8.4 11.2 27 4.9 11.3 2.4 1 1 0 1 1 1 0 Double zinc ribbon Translin PF01997.16 EGO55440.1 - 8.5e-59 199.0 0.0 1.1e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Translin family MRI PF15325.6 EGO55440.1 - 0.74 10.9 4.6 6.9 7.8 0.8 2.4 2 0 0 2 2 2 0 Modulator of retrovirus infection Amidohydro_2 PF04909.14 EGO55441.1 - 5.5e-51 174.1 1.2 6.7e-51 173.8 1.2 1.1 1 0 0 1 1 1 1 Amidohydrolase Mannosyl_trans PF05007.13 EGO55442.1 - 3.5e-82 276.2 9.5 4.8e-82 275.7 9.5 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EGO55442.1 - 7.9e-16 58.1 0.0 7.9e-16 58.1 0.0 2.2 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U Wzy_C_2 PF11846.8 EGO55442.1 - 0.02 14.8 0.3 0.02 14.8 0.3 3.0 3 1 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal F-box-like PF12937.7 EGO55443.1 - 5.7e-05 22.9 0.0 0.0003 20.6 0.0 2.2 2 1 0 2 2 2 1 F-box-like Peptidase_S8 PF00082.22 EGO55445.1 - 8.1e-31 107.4 15.2 2.3e-30 105.9 15.2 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGO55445.1 - 0.0011 19.6 0.1 0.0021 18.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 SQS_PSY PF00494.19 EGO55446.1 - 7.4e-37 127.3 0.0 1.6e-36 126.2 0.0 1.5 2 0 0 2 2 2 1 Squalene/phytoene synthase Cbl_N2 PF02761.14 EGO55446.1 - 0.081 13.7 1.2 25 5.7 0.0 3.1 3 0 0 3 3 3 0 CBL proto-oncogene N-terminus, EF hand-like domain tRNA_lig_CPD PF08302.11 EGO55446.1 - 0.16 11.4 0.4 0.85 9.0 0.0 2.0 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain RmlD_sub_bind PF04321.17 EGO55447.1 - 2.4e-14 53.1 0.0 4e-14 52.4 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EGO55447.1 - 1.6e-13 50.7 0.0 2.7e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGO55447.1 - 0.00019 20.7 0.0 0.00056 19.1 0.0 1.7 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EGO55447.1 - 0.00069 19.1 0.0 0.002 17.6 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGO55447.1 - 0.011 14.8 0.0 0.024 13.7 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DnaJ-X PF14308.6 EGO55448.1 - 1.3e-78 263.2 4.4 1.3e-78 263.2 4.4 2.1 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGO55448.1 - 7.4e-27 93.3 1.2 1.6e-26 92.2 1.2 1.6 1 0 0 1 1 1 1 DnaJ domain Cyt-b5 PF00173.28 EGO55449.1 - 1.9e-15 56.7 0.0 3e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ETRAMP PF09716.10 EGO55451.1 - 0.12 12.5 1.3 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) NIBRIN_BRCT_II PF16508.5 EGO55452.1 - 1.7e-35 121.9 0.0 4.6e-35 120.5 0.0 1.8 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein RTT107_BRCT_5 PF16770.5 EGO55452.1 - 4.1e-05 23.4 0.0 8.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 EGO55452.1 - 0.033 14.6 0.1 0.17 12.3 0.1 2.1 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Ribosomal_S30 PF04758.14 EGO55453.1 - 2.7e-28 97.9 5.3 3e-28 97.8 5.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_S5 PF00333.20 EGO55454.1 - 2e-27 95.0 1.0 5.1e-27 93.6 1.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EGO55454.1 - 6.9e-23 79.9 0.0 1.1e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 EGO55454.1 - 5.4 7.6 14.4 13 6.5 14.4 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 WSC PF01822.19 EGO55456.1 - 0.00082 19.5 0.9 0.0013 18.9 0.9 1.3 1 0 0 1 1 1 1 WSC domain Peptidase_M61_N PF17899.1 EGO55456.1 - 0.064 13.3 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase M61 N-terminal domain Gpr1_Fun34_YaaH PF01184.19 EGO55459.1 - 9e-91 303.1 17.7 1.1e-90 302.8 17.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Med3 PF11593.8 EGO55459.1 - 0.23 10.6 4.9 0.34 10.0 4.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FAD_binding_2 PF00890.24 EGO55460.1 - 9.4e-53 179.8 4.3 1.3e-52 179.3 4.3 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGO55460.1 - 8.2e-08 32.2 0.4 1.5e-07 31.4 0.4 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGO55460.1 - 9.4e-07 28.5 0.2 1.4e-06 28.0 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO55460.1 - 6.7e-06 26.2 2.1 1.7e-05 25.0 0.9 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGO55460.1 - 0.012 14.8 0.8 0.023 13.9 0.4 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 EGO55460.1 - 0.016 14.5 0.1 0.033 13.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO55460.1 - 0.022 13.5 0.6 0.022 13.5 0.6 2.3 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 EGO55460.1 - 0.024 13.7 7.6 0.025 13.7 2.7 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EGO55460.1 - 0.043 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EGO55460.1 - 0.09 12.0 0.5 0.17 11.1 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EGO55460.1 - 0.13 11.2 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EGO55460.1 - 0.18 11.1 0.9 0.28 10.4 0.9 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sulfatase PF00884.23 EGO55461.1 - 2e-73 247.5 0.3 2.5e-73 247.2 0.3 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGO55461.1 - 0.00019 21.2 2.6 0.0041 16.8 2.6 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 EGO55461.1 - 0.081 13.2 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) MFS_1 PF07690.16 EGO55462.1 - 2.2e-24 86.0 34.6 2.2e-24 86.0 34.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO55462.1 - 2.2e-11 43.3 18.7 1.2e-09 37.6 3.9 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter WD40 PF00400.32 EGO55463.1 - 1.2e-13 51.3 5.8 1.8e-05 25.4 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Ribosomal_L36 PF00444.18 EGO55464.1 - 1.9e-20 72.8 9.2 1.9e-20 72.8 9.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L36 DUF5473 PF17567.2 EGO55464.1 - 0.58 10.5 8.1 0.74 10.1 7.5 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5473) Glycos_trans_3N PF02885.17 EGO55465.1 - 0.054 13.4 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain E1_dh PF00676.20 EGO55465.1 - 0.15 11.0 0.1 2.8 6.8 0.0 2.0 2 0 0 2 2 2 0 Dehydrogenase E1 component DUF2156 PF09924.9 EGO55465.1 - 0.15 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) EF1_GNE PF00736.19 EGO55467.1 - 6e-33 112.9 0.9 9.3e-33 112.3 0.9 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EGO55467.1 - 6.2e-15 55.3 8.6 6.2e-15 55.3 8.6 2.5 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 EGO55467.1 - 0.00043 20.4 0.4 0.0046 17.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO55467.1 - 0.045 14.0 0.3 0.045 14.0 0.3 2.5 3 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain MARVEL PF01284.23 EGO55468.1 - 5.5e-12 45.9 20.4 7e-12 45.6 20.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain Fig1 PF12351.8 EGO55468.1 - 8.4 6.3 15.6 34 4.3 15.6 1.8 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 PIG-S PF10510.9 EGO55469.1 - 6.2e-173 576.3 0.8 7.2e-173 576.1 0.8 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Kelch_3 PF13415.6 EGO55470.1 - 1.8e-12 47.2 1.9 7.4e-09 35.7 0.0 5.1 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_4 PF13418.6 EGO55470.1 - 5.8e-09 35.8 0.1 0.0018 18.2 0.0 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EGO55470.1 - 1.5e-08 34.4 0.0 0.002 18.1 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 EGO55470.1 - 7e-08 32.5 0.5 0.11 12.8 0.0 4.6 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.15 EGO55470.1 - 0.00016 21.5 0.0 0.0022 17.9 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 EGO55470.1 - 0.0002 20.8 0.0 1.2 8.8 0.0 3.7 4 0 0 4 4 4 2 Kelch motif BTB PF00651.31 EGO55470.1 - 0.0082 16.4 0.0 0.21 11.8 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain CTP_transf_like PF01467.26 EGO55471.1 - 0.00041 20.6 0.1 0.77 9.9 0.0 2.7 2 1 0 2 2 2 2 Cytidylyltransferase-like Fungal_trans PF04082.18 EGO55472.1 - 5e-25 88.0 0.0 7.7e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO55472.1 - 2.3e-06 27.6 10.3 3.8e-06 26.9 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Shikimate_dh_N PF08501.11 EGO55473.1 - 1.7e-23 82.7 0.1 4.2e-23 81.4 0.1 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain DHquinase_I PF01487.15 EGO55473.1 - 1.3e-21 77.9 0.0 2.2e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SDH_C PF18317.1 EGO55473.1 - 5e-10 39.0 0.2 1.1e-09 37.9 0.2 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EGO55473.1 - 2.2e-07 31.0 0.1 4.2e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SKI PF01202.22 EGO55473.1 - 1.5e-06 28.4 0.0 2.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase AAA_29 PF13555.6 EGO55473.1 - 0.021 14.6 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGO55473.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sugar_tr PF00083.24 EGO55474.1 - 4e-144 480.8 24.6 4.6e-144 480.6 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO55474.1 - 6.1e-22 78.0 45.6 4.2e-21 75.3 42.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Shikimate_dh_N PF08501.11 EGO55475.1 - 1.9e-19 69.7 0.0 3.2e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EGO55475.1 - 9.7e-06 25.3 0.2 3.1e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EGO55475.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.15 EGO55475.1 - 0.034 13.1 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family VESA1_N PF12785.7 EGO55475.1 - 0.15 11.0 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 AP_endonuc_2 PF01261.24 EGO55476.1 - 1.6e-41 142.0 0.0 2.1e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Carot_N PF09150.10 EGO55476.1 - 0.035 14.0 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal PAC2 PF09754.9 EGO55476.1 - 0.082 12.9 0.0 8.3 6.3 0.0 2.3 2 0 0 2 2 2 0 PAC2 family Epimerase PF01370.21 EGO55476.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DHquinase_II PF01220.19 EGO55477.1 - 8.3e-59 197.2 0.0 1.1e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 Dehydroquinase class II Inositol_P PF00459.25 EGO55478.1 - 4.7e-87 292.0 0.0 5.4e-87 291.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family ANAPC4_WD40 PF12894.7 EGO55479.1 - 4.5e-06 26.9 0.0 0.038 14.3 0.0 3.2 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO55479.1 - 0.002 18.9 6.6 0.6 11.1 0.0 5.4 7 0 0 7 7 7 1 WD domain, G-beta repeat BUD22 PF09073.10 EGO55479.1 - 0.0034 16.8 1.5 0.0034 16.8 1.5 1.7 2 1 0 2 2 2 1 BUD22 CDC45 PF02724.14 EGO55479.1 - 0.45 8.8 3.3 0.78 8.0 3.3 1.3 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 EGO55479.1 - 8.7 6.4 11.9 64 3.5 9.5 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Glyco_hydro_18 PF00704.28 EGO55480.1 - 8.6e-65 219.5 0.0 1e-64 219.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Abhydrolase_6 PF12697.7 EGO55481.1 - 3.7e-12 47.3 13.7 6.6e-11 43.2 13.7 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO55481.1 - 0.0005 19.8 0.0 0.0011 18.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold 23ISL PF16620.5 EGO55481.1 - 0.054 13.7 1.0 0.094 12.9 1.0 1.3 1 0 0 1 1 1 0 Unstructured linker between I-set domains 2 and 3 on MYLCK PPP4R2 PF09184.11 EGO55482.1 - 0.061 12.9 12.8 0.074 12.6 12.8 1.2 1 0 0 1 1 1 0 PPP4R2 DUF4551 PF15087.6 EGO55482.1 - 0.79 8.5 6.3 0.88 8.3 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PNISR PF15996.5 EGO55482.1 - 1.7 8.9 13.0 0.9 9.8 1.5 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR DHH PF01368.20 EGO55484.1 - 0.052 13.8 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 DHH family Rhodanese PF00581.20 EGO55485.1 - 1.5e-16 60.8 0.0 6.7e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain DUF5476 PF17570.2 EGO55485.1 - 0.26 11.7 1.6 0.42 11.0 0.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5476) zf-ANAPC11 PF12861.7 EGO55486.1 - 3.6e-45 152.0 11.5 3.9e-45 151.8 11.5 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGO55486.1 - 9.9e-22 77.0 12.4 1.3e-21 76.6 12.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGO55486.1 - 6.5e-08 32.8 15.9 1.6e-06 28.4 15.9 2.4 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGO55486.1 - 2.3e-05 24.3 9.1 0.00017 21.6 5.2 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGO55486.1 - 0.00011 22.0 14.7 0.00048 19.9 14.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGO55486.1 - 0.0008 19.0 11.2 0.0055 16.3 11.2 2.0 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EGO55486.1 - 0.0013 18.6 8.1 0.0013 18.6 8.1 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EGO55486.1 - 0.0026 17.5 2.5 0.0026 17.5 2.5 2.4 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 EGO55486.1 - 0.0049 17.0 17.4 0.14 12.3 17.4 3.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 EGO55486.1 - 0.0075 16.4 8.8 0.0075 16.4 8.8 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EGO55486.1 - 0.0099 15.7 18.7 0.019 14.8 14.4 2.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 EGO55486.1 - 0.01 15.7 5.0 0.017 15.0 5.0 1.4 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 EGO55486.1 - 0.031 14.0 10.8 0.27 11.0 9.1 2.8 2 1 0 2 2 2 0 RING-like zinc finger zf-HIT PF04438.16 EGO55486.1 - 0.056 13.3 1.5 0.056 13.3 1.5 2.4 3 0 0 3 3 2 0 HIT zinc finger Rad50_zn_hook PF04423.14 EGO55486.1 - 0.11 12.4 4.8 0.15 11.9 0.0 2.5 2 1 0 2 2 2 0 Rad50 zinc hook motif zf-RING_5 PF14634.6 EGO55486.1 - 0.25 11.3 18.0 12 6.0 18.5 2.9 1 1 1 2 2 2 0 zinc-RING finger domain YacG PF03884.14 EGO55486.1 - 0.35 10.6 7.5 0.35 10.6 0.3 2.7 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG UBZ_FAAP20 PF15750.5 EGO55486.1 - 0.52 10.3 6.7 1.7 8.6 0.3 2.8 2 1 1 3 3 3 0 Ubiquitin-binding zinc-finger zf-RING-like PF08746.11 EGO55486.1 - 1.3 9.4 13.6 1.8 8.9 11.1 2.2 1 1 1 2 2 2 0 RING-like domain Opy2 PF09463.10 EGO55486.1 - 1.7 9.1 11.6 3.9 7.9 6.8 2.4 2 1 0 2 2 2 0 Opy2 protein RINGv PF12906.7 EGO55486.1 - 3.5 7.8 14.4 3.3 7.9 12.3 2.1 1 1 1 2 2 2 0 RING-variant domain DZR PF12773.7 EGO55486.1 - 4 7.5 13.5 3.1 7.9 6.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon Rubredoxin_2 PF18073.1 EGO55486.1 - 7.5 6.4 11.1 8.8 6.2 0.4 3.7 3 0 0 3 3 3 0 Rubredoxin metal binding domain Acyl-thio_N PF12590.8 EGO55487.1 - 0.21 12.1 3.3 9.3 6.8 0.9 2.4 2 0 0 2 2 2 0 Acyl-ATP thioesterase Syntaxin PF00804.25 EGO55488.1 - 2.9e-19 69.5 13.9 2.9e-19 69.5 13.9 2.2 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.19 EGO55488.1 - 2.6e-11 43.3 5.0 2.6e-11 43.3 5.0 2.8 3 1 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 EGO55488.1 - 1.1e-05 25.8 9.3 8.7e-05 22.8 2.1 2.5 2 0 0 2 2 2 2 Syntaxin-like protein Use1 PF09753.9 EGO55488.1 - 0.00082 19.2 8.1 0.0013 18.5 8.1 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 Spectrin PF00435.21 EGO55488.1 - 0.0011 19.5 10.7 0.076 13.5 0.0 3.3 2 1 1 3 3 3 3 Spectrin repeat ODV-E18 PF10717.9 EGO55488.1 - 0.0034 17.2 0.1 0.0079 16.0 0.1 1.5 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 Mod_r PF07200.13 EGO55488.1 - 0.023 14.8 13.3 0.91 9.6 2.6 2.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Orf78 PF06024.12 EGO55488.1 - 0.025 14.9 0.5 0.084 13.2 0.5 1.9 1 0 0 1 1 1 0 Orf78 (ac78) PspA_IM30 PF04012.12 EGO55488.1 - 3.1 7.3 20.0 0.57 9.7 15.8 1.8 2 0 0 2 2 2 0 PspA/IM30 family MCU PF04678.13 EGO55488.1 - 3.1 7.8 9.3 0.59 10.2 2.7 2.3 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Memo PF01875.17 EGO55489.1 - 3.7e-70 236.1 0.0 4.3e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein DUF4545 PF15078.6 EGO55490.1 - 0.041 12.9 0.7 0.052 12.6 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4545) IMS PF00817.20 EGO55491.1 - 5e-42 143.4 0.1 8.6e-42 142.7 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EGO55491.1 - 8e-15 55.6 0.7 1.7e-14 54.5 0.7 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EGO55491.1 - 2.3e-06 27.6 0.0 5.7e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Ribosomal_L19e PF01280.20 EGO55491.1 - 0.1 12.7 0.6 0.22 11.6 0.6 1.5 1 0 0 1 1 1 0 Ribosomal protein L19e TrkH PF02386.16 EGO55492.1 - 2.7e-97 326.3 4.4 1.6e-94 317.2 0.1 2.1 2 0 0 2 2 2 2 Cation transport protein HemN_C PF06969.16 EGO55494.1 - 0.054 13.6 0.0 0.08 13.0 0.0 1.4 1 1 0 1 1 1 0 HemN C-terminal domain FKBP_C PF00254.28 EGO55495.1 - 2.2e-32 111.2 0.0 4e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Apolipoprotein PF01442.18 EGO55495.1 - 0.016 15.1 6.3 0.024 14.5 6.3 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain MT0933_antitox PF14013.6 EGO55495.1 - 0.026 14.8 16.3 0.028 14.7 12.3 2.5 3 0 0 3 3 3 0 MT0933-like antitoxin protein Remorin_C PF03763.13 EGO55495.1 - 0.41 10.6 8.7 0.65 9.9 8.7 1.2 1 0 0 1 1 1 0 Remorin, C-terminal region ApoLp-III PF07464.11 EGO55495.1 - 0.48 10.5 8.9 0.79 9.8 8.9 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 EGO55495.1 - 0.69 10.5 8.9 1.7 9.3 8.9 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) LEA_4 PF02987.16 EGO55495.1 - 0.87 9.7 19.5 0.21 11.7 11.8 2.3 1 1 1 2 2 2 0 Late embryogenesis abundant protein ATP-synt_B PF00430.18 EGO55495.1 - 2.1 8.4 12.9 3 7.9 12.9 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) RPEL PF02755.15 EGO55498.1 - 2.3e-16 58.9 5.3 1.1e-08 34.5 1.3 3.2 4 0 0 4 4 4 2 RPEL repeat zf-H2C2_5 PF13909.6 EGO55498.1 - 0.54 10.1 3.6 7.9 6.3 0.8 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain TLD PF07534.16 EGO55499.1 - 3.8e-27 95.2 0.0 2.9e-26 92.3 0.0 2.1 1 1 0 1 1 1 1 TLD DUF1773 PF08593.10 EGO55499.1 - 3e-12 47.4 0.2 7.2e-12 46.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function HIG_1_N PF04588.13 EGO55500.1 - 1.6e-24 85.8 1.9 2.9e-24 85.0 1.9 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Fibrinogen_BP PF08017.11 EGO55500.1 - 0.0048 15.4 1.2 0.0062 15.0 1.2 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein INCA1 PF15142.6 EGO55500.1 - 0.0087 16.1 0.5 0.47 10.5 0.8 2.0 1 1 1 2 2 2 1 INCA1 DUF5621 PF18532.1 EGO55500.1 - 0.043 13.7 0.6 0.067 13.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5621) DUF4093 PF13331.6 EGO55500.1 - 0.064 13.7 0.3 0.11 13.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4093) Peptidase_S49_N PF08496.10 EGO55500.1 - 0.26 11.3 4.3 0.37 10.8 4.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4407 PF14362.6 EGO55500.1 - 0.78 9.0 7.2 1 8.7 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PALP PF00291.25 EGO55501.1 - 2.4e-78 263.5 0.8 3e-78 263.2 0.8 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EGO55501.1 - 4.4e-32 109.7 0.0 1.4e-17 63.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HU-HIG PF18291.1 EGO55501.1 - 0.17 12.0 0.0 0.58 10.3 0.0 1.9 2 0 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif Abhydrolase_2 PF02230.16 EGO55503.1 - 0.034 13.9 0.0 0.042 13.7 0.0 1.4 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF5396 PF17374.2 EGO55503.1 - 0.25 9.1 8.2 0.29 8.9 8.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5396) IRF-2BP1_2 PF11261.8 EGO55506.1 - 0.11 12.1 0.8 0.3 10.7 0.3 1.8 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger RVT_1 PF00078.27 EGO55515.1 - 5.8e-07 29.3 0.5 6e-07 29.2 0.5 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2-oxoacid_dh PF00198.23 EGO55516.1 - 2.5e-81 272.5 0.1 3.7e-81 272.0 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGO55516.1 - 8.1e-20 70.4 2.3 1.7e-19 69.4 2.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGO55516.1 - 7.9e-06 25.6 0.5 0.01 15.6 0.0 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 EGO55516.1 - 0.0006 20.5 0.4 1.4 9.7 0.1 2.4 1 1 1 2 2 2 2 HlyD family secretion protein RnfC_N PF13375.6 EGO55516.1 - 0.026 14.5 0.4 0.58 10.1 0.0 2.5 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 EGO55516.1 - 0.027 14.4 0.3 0.051 13.5 0.3 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF2868 PF11067.8 EGO55516.1 - 0.26 10.8 2.3 0.44 10.0 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) CCDC53 PF10152.9 EGO55516.1 - 1.1 9.7 4.8 1.7 9.0 4.8 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Histone_H2A_C PF16211.5 EGO55517.1 - 2.2e-21 75.3 3.1 3.8e-21 74.5 3.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGO55517.1 - 6.9e-17 62.0 0.0 9.3e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGO55517.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LcrG PF07216.12 EGO55517.1 - 0.093 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 LcrG protein Histone PF00125.24 EGO55519.1 - 2.1e-21 76.6 1.5 2.6e-21 76.3 1.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGO55519.1 - 4.2e-05 23.7 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGO55519.1 - 0.00025 21.5 0.0 0.00043 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 EGO55519.1 - 0.037 13.7 0.1 0.09 12.4 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain R3H PF01424.22 EGO55520.1 - 5.3e-14 52.0 0.0 1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 EGO55520.1 - 1.4e-12 47.3 4.8 2.9e-12 46.3 4.8 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGO55520.1 - 0.008 16.3 2.5 0.008 16.3 2.5 2.4 3 0 0 3 3 3 1 G-patch domain Peptidase_C54 PF03416.19 EGO55521.1 - 4.3e-92 308.4 0.0 5.3e-92 308.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 DnaJ PF00226.31 EGO55522.1 - 2.4e-24 85.2 0.9 2.4e-24 85.2 0.9 2.4 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 EGO55522.1 - 1e-10 41.6 2.2 1e-10 41.6 2.2 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGO55522.1 - 6.8e-10 39.2 4.6 1.7e-05 25.1 0.7 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EGO55522.1 - 4e-09 36.6 9.1 4.7e-09 36.3 2.5 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EGO55522.1 - 4.3e-06 27.1 5.5 0.015 16.1 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO55522.1 - 5.8e-05 23.3 8.1 0.01 16.2 0.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGO55522.1 - 0.0011 19.0 10.0 0.0052 16.7 1.6 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf_Hakai PF18408.1 EGO55522.1 - 0.0045 16.7 0.4 3 7.6 0.0 2.3 2 0 0 2 2 2 2 C2H2 Hakai zinc finger domain Lact-deh-memb PF09330.11 EGO55522.1 - 0.051 12.9 0.7 0.082 12.2 0.7 1.2 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding Tmemb_55A PF09788.9 EGO55522.1 - 0.1 11.7 3.0 0.059 12.4 0.9 1.6 2 0 0 2 2 2 0 Transmembrane protein 55A DUF4451 PF14616.6 EGO55522.1 - 0.12 12.5 0.9 5.6 7.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) zf-C2H2_3rep PF18868.1 EGO55522.1 - 0.17 12.5 5.7 2.2 9.0 0.6 3.0 3 0 0 3 3 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 EGO55522.1 - 0.36 11.3 1.4 6.1 7.5 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain DUF2256 PF10013.9 EGO55522.1 - 1.2 9.3 4.9 15 5.8 0.0 2.8 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2256) AKAP95 PF04988.12 EGO55522.1 - 5.4 7.2 10.4 0.093 13.0 1.9 2.2 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) SPX PF03105.19 EGO55523.1 - 3e-52 178.9 0.7 8.4e-51 174.1 0.7 2.1 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 EGO55523.1 - 0.00012 21.8 11.6 0.00022 21.0 11.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO55523.1 - 0.00031 20.5 13.7 0.00065 19.5 13.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO55523.1 - 0.00084 19.6 13.6 0.0018 18.6 13.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 EGO55523.1 - 0.0011 19.0 12.8 0.0022 18.1 12.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EGO55523.1 - 0.0027 17.5 14.2 0.005 16.6 14.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO55523.1 - 0.01 15.8 11.5 0.028 14.4 11.5 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 EGO55523.1 - 0.01 15.6 4.6 0.01 15.6 4.6 1.8 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EGO55523.1 - 0.036 13.9 8.7 0.085 12.7 8.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGO55523.1 - 0.75 9.9 11.2 2.2 8.4 11.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 EGO55523.1 - 2.4 8.5 10.3 5.8 7.3 10.3 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain FYVE_2 PF02318.16 EGO55523.1 - 7.5 6.8 11.7 6.9 6.9 9.5 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger Cys_Met_Meta_PP PF01053.20 EGO55524.1 - 5.5e-37 127.2 0.0 7.9e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGO55524.1 - 0.0027 16.9 0.0 0.007 15.6 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II CMD PF02627.20 EGO55524.1 - 0.025 14.6 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Glyoxalase PF00903.25 EGO55525.1 - 0.018 15.2 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EMG1 PF03587.14 EGO55526.1 - 3.4e-79 265.0 0.0 4e-79 264.8 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase PH PF00169.29 EGO55528.1 - 0.0064 17.0 0.0 0.029 14.9 0.0 2.1 2 0 0 2 2 2 1 PH domain Prominin PF05478.11 EGO55528.1 - 0.048 11.6 0.2 0.071 11.1 0.2 1.2 1 0 0 1 1 1 0 Prominin WEMBL PF05701.11 EGO55528.1 - 0.15 10.7 2.2 0.22 10.2 2.2 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light SUIM_assoc PF16619.5 EGO55528.1 - 1 9.5 12.7 3.6 7.7 12.7 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 EGO55528.1 - 1.3 9.0 10.6 0.19 11.7 6.2 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EGO55528.1 - 7.7 6.0 12.8 16 5.1 12.8 1.4 1 0 0 1 1 1 0 Spt20 family DnaJ PF00226.31 EGO55529.1 - 9.6e-22 76.9 1.9 9.6e-22 76.9 1.9 2.2 3 0 0 3 3 2 1 DnaJ domain TPR_1 PF00515.28 EGO55529.1 - 5.7e-18 63.9 2.5 0.001 18.8 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGO55529.1 - 2.5e-15 55.3 14.8 0.056 13.6 0.0 8.6 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGO55529.1 - 3.7e-13 49.4 0.3 0.00092 19.3 0.0 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGO55529.1 - 7.8e-12 45.0 9.2 0.056 14.3 0.1 6.8 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO55529.1 - 2.3e-10 39.9 0.9 0.26 11.6 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO55529.1 - 2.8e-09 37.3 13.3 0.0032 18.0 0.8 5.2 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGO55529.1 - 1.5e-08 34.1 5.5 0.023 14.4 0.0 5.2 4 1 1 5 5 4 3 TPR repeat TPR_6 PF13174.6 EGO55529.1 - 2.2e-08 34.2 18.4 0.019 15.6 1.3 7.3 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGO55529.1 - 8.7e-07 28.5 4.6 0.31 11.2 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGO55529.1 - 2.2e-05 24.5 5.7 0.00052 20.2 0.0 5.3 6 0 0 6 6 4 1 Tetratricopeptide repeat PknG_TPR PF16918.5 EGO55529.1 - 0.00035 19.4 4.8 0.002 16.9 1.8 2.8 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_12 PF13424.6 EGO55529.1 - 0.00064 20.0 11.1 2.3 8.6 0.1 4.8 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGO55529.1 - 0.0021 18.6 19.3 3.9 8.2 0.1 6.2 4 1 0 5 5 5 2 Tetratricopeptide repeat DUF3856 PF12968.7 EGO55529.1 - 0.0054 16.8 2.7 0.78 9.8 0.3 3.7 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) IFT46_B_C PF12317.8 EGO55529.1 - 0.0068 16.2 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal TPR_15 PF13429.6 EGO55529.1 - 0.031 13.5 6.7 1.9 7.6 0.2 4.2 3 2 1 4 4 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EGO55529.1 - 0.24 11.9 5.4 17 5.8 0.0 3.5 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation ANAPC3 PF12895.7 EGO55529.1 - 0.26 11.5 16.1 2.4 8.5 0.1 4.8 3 2 3 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 EGO55529.1 - 0.36 11.2 9.7 9.8 6.6 0.0 4.4 2 2 3 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 EGO55529.1 - 0.62 10.5 8.5 9.7 6.6 0.0 4.3 4 1 2 6 6 4 0 Bacterial transcriptional activator domain BAR PF03114.18 EGO55529.1 - 0.89 9.2 0.0 0.89 9.2 0.0 2.7 2 1 0 2 2 1 0 BAR domain TPR_10 PF13374.6 EGO55529.1 - 1.5 8.8 9.1 7.9 6.5 0.7 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TipAS PF07739.13 EGO55529.1 - 1.9 9.1 10.0 1.9 9.0 0.4 3.3 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Mito_carr PF00153.27 EGO55530.1 - 6.9e-69 227.8 4.5 4.2e-23 81.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGO55530.1 - 0.0023 17.1 6.2 0.4 9.8 5.1 3.5 1 1 1 2 2 2 1 Gammaproteobacterial serine protease APG9 PF04109.16 EGO55531.1 - 1.7e-200 667.1 13.1 2e-200 666.9 13.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 COG6 PF06419.11 EGO55532.1 - 1.5e-211 704.0 5.9 1.7e-211 703.8 5.9 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.11 EGO55532.1 - 0.004 17.2 1.1 0.031 14.4 1.1 2.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DASH_Dad3 PF08656.10 EGO55532.1 - 0.014 15.5 0.1 0.13 12.3 0.0 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad3 SPACA9 PF15120.6 EGO55532.1 - 0.13 12.0 2.4 0.27 11.0 0.2 2.6 4 0 0 4 4 4 0 Sperm acrosome-associated protein 9 LytR_C PF13399.6 EGO55532.1 - 0.17 12.9 0.0 0.53 11.3 0.0 1.8 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator Med9 PF07544.13 EGO55532.1 - 1.1 9.3 4.1 0.81 9.8 0.5 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 AAA PF00004.29 EGO55533.1 - 3e-16 60.1 1.7 1.6e-10 41.5 0.1 2.7 2 1 1 3 3 2 2 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EGO55533.1 - 6.5e-10 38.9 1.4 1.2e-07 31.6 0.0 3.3 4 0 0 4 4 3 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 EGO55533.1 - 2.1e-08 33.8 0.0 5.2e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGO55533.1 - 2.7e-05 24.6 1.3 0.0036 17.7 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EGO55533.1 - 0.00038 20.7 0.0 0.0015 18.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 EGO55533.1 - 0.00066 19.5 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGO55533.1 - 0.0029 17.6 0.0 0.0096 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EGO55533.1 - 0.0041 17.0 3.8 0.01 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGO55533.1 - 0.0044 16.4 0.5 0.0098 15.3 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGO55533.1 - 0.0044 17.2 0.2 0.017 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Guanylate_kin PF00625.21 EGO55533.1 - 0.006 16.3 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase IstB_IS21 PF01695.17 EGO55533.1 - 0.0084 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EGO55533.1 - 0.0086 15.3 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 EGO55533.1 - 0.017 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EGO55533.1 - 0.021 14.4 0.0 0.079 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EGO55533.1 - 0.023 13.8 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 EGO55533.1 - 0.039 14.2 0.9 0.47 10.7 0.3 2.8 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGO55533.1 - 0.046 14.3 0.0 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.17 EGO55533.1 - 0.06 13.5 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_24 PF13479.6 EGO55533.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGO55533.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EGO55533.1 - 0.13 12.6 0.0 0.56 10.6 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 EGO55533.1 - 0.2 11.5 0.0 0.58 10.0 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Ribosomal_S17 PF00366.20 EGO55534.1 - 3.3e-18 65.5 0.4 6.1e-18 64.7 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 GAS2 PF02187.17 EGO55534.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain SQHop_cyclase_N PF13249.6 EGO55534.1 - 0.076 12.1 0.3 0.11 11.6 0.3 1.1 1 0 0 1 1 1 0 Squalene-hopene cyclase N-terminal domain Se-cys_synth_N PF12390.8 EGO55534.1 - 0.57 10.4 2.3 4.4 7.6 1.5 2.7 2 1 0 2 2 2 0 Selenocysteine synthase N terminal DUF2013 PF09431.10 EGO55535.1 - 2.8e-21 76.1 1.9 5.5e-21 75.2 1.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Acetyltransf_1 PF00583.25 EGO55536.1 - 2e-19 69.9 0.0 2.7e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO55536.1 - 8.3e-11 41.9 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO55536.1 - 2.8e-10 40.0 0.0 7.4e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 EGO55536.1 - 3.8e-10 40.1 0.0 5.8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGO55536.1 - 1.1e-07 32.6 0.0 1.5e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGO55536.1 - 2.3e-06 27.4 0.0 3.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGO55536.1 - 4.4e-06 26.8 0.0 9.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGO55536.1 - 0.003 17.7 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 EGO55536.1 - 0.017 15.1 0.1 0.086 12.8 0.0 2.1 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase LCAT PF02450.15 EGO55537.1 - 5.2e-105 351.8 0.0 6.4e-105 351.5 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 EGO55537.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Metallopep PF12044.8 EGO55538.1 - 1.3e-173 577.5 0.0 1.6e-173 577.2 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 EGO55538.1 - 3.1e-05 23.9 0.1 5.6e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Peptidase_M10 PF00413.24 EGO55538.1 - 0.04 13.7 0.0 0.099 12.5 0.0 1.6 1 1 0 1 1 1 0 Matrixin Asp2 PF16929.5 EGO55538.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Peptidase_M66 PF10462.9 EGO55538.1 - 0.22 10.4 0.4 0.37 9.7 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 W2 PF02020.18 EGO55539.1 - 1.3e-19 70.1 2.5 5.1e-19 68.2 2.5 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 EGO55539.1 - 7.7e-07 28.6 3.4 0.0023 17.6 0.3 3.4 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EGO55539.1 - 0.00035 20.2 0.0 0.00065 19.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 EGO55539.1 - 0.0013 17.0 0.1 0.002 16.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EGO55539.1 - 0.0086 15.1 1.4 0.39 9.6 0.2 2.3 1 1 1 2 2 2 2 L-fucokinase NTP_transf_3 PF12804.7 EGO55539.1 - 0.087 13.2 0.0 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EGO55539.1 - 0.13 12.0 0.1 14 5.6 0.3 3.4 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase HSF_DNA-bind PF00447.17 EGO55541.1 - 2.4e-32 111.4 1.5 5.5e-32 110.3 1.5 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 EGO55541.1 - 8.5e-23 80.7 0.3 2.3e-22 79.3 0.5 1.7 2 0 0 2 2 2 1 Response regulator receiver domain CENP-H PF05837.12 EGO55541.1 - 0.0054 17.1 4.7 0.012 16.0 4.7 1.6 1 0 0 1 1 1 1 Centromere protein H (CENP-H) CENP-Q PF13094.6 EGO55541.1 - 0.011 15.9 1.4 0.024 14.8 1.4 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HAP1_N PF04849.13 EGO55541.1 - 0.14 11.3 3.0 0.21 10.7 3.0 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region YabA PF06156.13 EGO55541.1 - 0.16 12.6 1.4 0.37 11.5 1.4 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Ets PF00178.22 EGO55541.1 - 0.17 12.3 0.1 0.5 10.9 0.1 1.7 1 0 0 1 1 1 0 Ets-domain Whi5 PF08528.11 EGO55544.1 - 1.3e-08 34.3 0.2 2.8e-08 33.2 0.2 1.6 1 0 0 1 1 1 1 Whi5 like Vac14_Fig4_bd PF11916.8 EGO55547.1 - 4.7e-82 274.0 9.2 9.7e-82 272.9 9.2 1.5 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EGO55547.1 - 3.2e-45 152.6 0.0 7.5e-41 138.7 0.0 4.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGO55547.1 - 2.8e-09 37.3 3.2 0.0046 17.4 0.1 5.0 5 0 0 5 5 5 3 HEAT-like repeat HEAT PF02985.22 EGO55547.1 - 1.7e-07 30.9 2.1 0.00064 19.8 0.0 5.3 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 EGO55547.1 - 1.7e-07 31.4 1.3 0.0012 18.9 0.5 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 EGO55547.1 - 0.0011 18.9 0.2 1.2 9.3 0.0 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGO55547.1 - 0.0046 17.3 2.1 3.1 8.3 0.0 4.6 5 0 0 5 5 5 1 HEAT repeats FA_desaturase PF00487.24 EGO55549.1 - 1.3e-23 84.1 27.9 2.1e-23 83.5 27.9 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGO55549.1 - 3.4e-11 43.1 0.0 6.4e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_2 PF07992.14 EGO55550.1 - 3.7e-68 229.9 6.6 5.1e-68 229.4 5.9 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGO55550.1 - 1.1e-40 138.3 0.1 3.2e-40 136.8 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGO55550.1 - 9.2e-23 80.6 10.3 1.1e-20 73.9 1.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO55550.1 - 8.6e-12 45.1 3.8 5.8e-06 26.4 0.7 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EGO55550.1 - 5.3e-10 39.2 8.6 4.3e-09 36.2 0.4 3.0 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO55550.1 - 7.5e-09 35.2 7.4 5e-07 29.2 3.3 3.1 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 EGO55550.1 - 7.7e-09 35.2 1.5 0.0003 20.1 0.2 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EGO55550.1 - 1.6e-08 34.1 12.5 1.2e-06 27.9 4.2 3.3 2 2 1 3 3 3 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EGO55550.1 - 2e-07 30.6 5.8 2.8e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO55550.1 - 1.9e-06 27.7 10.3 0.0046 16.6 0.3 3.9 4 0 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EGO55550.1 - 2.1e-06 26.7 12.8 0.00018 20.4 2.2 4.0 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.17 EGO55550.1 - 3.2e-06 26.5 2.4 5.8e-05 22.4 0.1 2.3 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 EGO55550.1 - 0.00018 20.8 0.3 0.8 8.8 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EGO55550.1 - 0.0024 17.2 11.1 0.4 9.9 1.4 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.6 EGO55550.1 - 0.0071 16.8 3.3 0.25 11.8 0.1 3.1 2 1 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EGO55550.1 - 0.015 14.4 5.9 0.13 11.3 1.2 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein THF_DHG_CYH_C PF02882.19 EGO55550.1 - 0.046 13.1 1.0 20 4.5 0.1 3.7 4 1 0 4 4 4 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Trp_halogenase PF04820.14 EGO55550.1 - 0.13 11.0 5.7 0.26 10.1 0.8 2.2 2 0 0 2 2 2 0 Tryptophan halogenase FMO-like PF00743.19 EGO55550.1 - 0.26 9.6 1.4 0.78 8.1 0.6 2.0 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like 3HCDH_N PF02737.18 EGO55550.1 - 1.1 9.1 7.2 0.22 11.4 0.3 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MIF4G PF02854.19 EGO55551.1 - 7.8e-24 84.5 0.1 1e-22 80.9 0.2 2.2 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 EGO55551.1 - 2.7e-17 62.8 0.0 1.2e-16 60.7 0.0 2.2 2 0 0 2 2 2 1 MA3 domain SRP14 PF02290.15 EGO55552.1 - 4.8e-26 91.0 0.0 7.5e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein RRM_1 PF00076.22 EGO55553.1 - 5.1e-55 183.2 0.0 3.9e-18 65.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EGO55553.1 - 2e-06 27.7 0.0 1.9 8.7 0.0 4.1 3 2 0 3 3 3 3 Limkain b1 RRM_3 PF08777.11 EGO55553.1 - 9.4e-06 25.6 0.0 0.75 9.9 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif ATP-grasp_2 PF08442.10 EGO55553.1 - 0.00056 19.5 0.0 0.045 13.3 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp domain RRM_5 PF13893.6 EGO55553.1 - 0.0019 17.8 0.0 0.49 10.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PknH_C PF14032.6 EGO55553.1 - 0.019 14.8 0.0 18 5.1 0.0 3.2 3 0 0 3 3 3 0 PknH-like extracellular domain RRM_occluded PF16842.5 EGO55553.1 - 0.024 14.5 0.0 23 4.9 0.0 3.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif BRAP2 PF07576.12 EGO55553.1 - 0.17 12.1 0.0 1.2 9.4 0.0 2.0 2 0 0 2 2 2 0 BRCA1-associated protein 2 COQ9 PF08511.11 EGO55558.1 - 3.1e-29 100.6 0.0 5.2e-29 99.8 0.0 1.4 1 0 0 1 1 1 1 COQ9 SSP160 PF06933.11 EGO55558.1 - 0.047 11.9 16.4 0.065 11.4 16.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TraG-D_C PF12696.7 EGO55558.1 - 0.81 9.7 4.0 2.7 8.0 3.7 2.0 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG DUF515 PF04415.12 EGO55558.1 - 0.99 7.7 15.5 1.4 7.3 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pex14_N PF04695.13 EGO55558.1 - 1.4 9.5 9.1 4.1 8.0 7.9 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NAM-associated PF14303.6 EGO55558.1 - 4.1 8.1 6.8 6.4 7.5 6.8 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Med3 PF11593.8 EGO55558.1 - 6.9 5.8 15.9 9.5 5.3 15.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FSA_C PF10479.9 EGO55558.1 - 7.9 4.5 8.1 10 4.1 8.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SMC_N PF02463.19 EGO55559.1 - 1.7e-25 89.8 0.1 4.2e-25 88.5 0.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGO55559.1 - 7.6e-18 65.7 0.2 7.6e-18 65.7 0.2 3.5 2 1 1 3 3 2 1 AAA domain AAA_15 PF13175.6 EGO55559.1 - 7.7e-10 39.0 14.6 5e-08 33.1 14.6 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EGO55559.1 - 1e-05 25.5 10.9 0.0005 20.0 0.2 3.6 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGO55559.1 - 0.00073 19.2 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EGO55559.1 - 0.0025 18.4 12.0 0.05 14.1 0.1 4.0 2 1 0 2 2 2 1 ABC transporter SbcCD_C PF13558.6 EGO55559.1 - 0.02 15.1 0.0 0.066 13.5 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Rx_N PF18052.1 EGO55559.1 - 0.033 14.5 0.3 0.033 14.5 0.3 3.0 3 0 0 3 3 3 0 Rx N-terminal domain DUF3584 PF12128.8 EGO55559.1 - 2.5 5.5 34.5 0.18 9.3 11.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 EGO55559.1 - 3.9 6.3 40.1 0.19 10.6 5.7 3.2 1 1 1 3 3 3 0 Spc7 kinetochore protein GAS PF13851.6 EGO55559.1 - 5.8 6.2 43.6 0.33 10.3 9.7 3.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding GIT_CC PF16559.5 EGO55559.1 - 6.4 6.7 8.3 13 5.7 0.6 2.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 EGO55559.1 - 7.3 6.7 16.6 2 8.5 2.6 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) MscS_porin PF12795.7 EGO55559.1 - 7.5 6.0 30.0 3.5 7.1 17.7 3.5 2 2 1 3 3 3 0 Mechanosensitive ion channel porin domain DHR10 PF18595.1 EGO55559.1 - 9.5 6.3 47.9 1.1 9.4 6.5 5.1 2 2 3 5 5 5 0 Designed helical repeat protein 10 domain SGT1 PF07093.11 EGO55560.1 - 5.6e-89 299.2 29.0 5.7e-81 272.7 0.1 3.5 2 1 0 3 3 3 3 SGT1 protein DUF3439 PF11921.8 EGO55560.1 - 0.0085 16.1 2.3 0.11 12.4 0.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) DUF3446 PF11928.8 EGO55560.1 - 0.04 14.2 8.4 0.13 12.6 1.0 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF3408 PF11888.8 EGO55560.1 - 0.27 11.4 5.0 0.066 13.4 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) V-SNARE PF05008.15 EGO55560.1 - 0.96 9.9 4.4 0.62 10.5 0.4 2.5 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Peptidase_C14 PF00656.22 EGO55561.1 - 3e-62 210.8 0.0 3.8e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EGO55561.1 - 0.2 11.6 0.7 0.62 10.0 0.0 2.1 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain CCDC53 PF10152.9 EGO55562.1 - 1.2 9.6 5.9 0.58 10.6 1.8 2.5 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex stn_TNFRSF12A PF12191.8 EGO55564.1 - 0.00075 19.7 1.0 0.0015 18.8 0.1 1.9 2 0 0 2 2 2 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain CcmD PF04995.14 EGO55564.1 - 0.067 13.3 2.6 0.14 12.3 2.6 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) TPP_enzyme_N PF02776.18 EGO55565.1 - 7.3e-33 113.6 0.0 1.2e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGO55565.1 - 7.8e-24 84.0 0.0 3e-23 82.1 0.0 2.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EGO55565.1 - 1.4e-11 44.4 0.7 2.6e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Evr1_Alr PF04777.13 EGO55566.1 - 9e-32 109.5 2.1 9.9e-32 109.4 0.8 1.7 2 0 0 2 2 2 1 Erv1 / Alr family HEM4 PF02602.15 EGO55567.1 - 7.9e-38 130.1 0.0 1e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TLD PF07534.16 EGO55568.1 - 4.6e-26 91.7 0.0 2.8e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 TLD Pkinase PF00069.25 EGO55569.1 - 1.2e-68 231.4 0.0 1.5e-68 231.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO55569.1 - 4.4e-32 111.4 0.0 5.8e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGO55569.1 - 0.00032 20.1 0.3 0.00053 19.4 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGO55569.1 - 0.00076 18.5 0.2 0.0012 17.9 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGO55569.1 - 0.0056 16.0 0.0 0.0098 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGO55569.1 - 0.025 14.5 0.2 0.053 13.4 0.2 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGO55569.1 - 0.048 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.11 EGO55569.1 - 0.1 12.9 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.19 EGO55569.1 - 0.12 12.1 0.2 0.38 10.5 0.2 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Qn_am_d_aII PF14930.6 EGO55570.1 - 0.064 13.6 0.0 0.071 13.4 0.0 1.1 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II Sec23_trunk PF04811.15 EGO55571.1 - 1.2e-71 241.1 0.0 2e-71 240.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGO55571.1 - 1.5e-19 69.7 0.0 5.9e-19 67.8 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EGO55571.1 - 2.4e-18 66.6 0.1 4.9e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EGO55571.1 - 1.4e-16 60.2 4.7 2.6e-16 59.4 4.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGO55571.1 - 2.7e-09 36.8 0.0 6.5e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EGO55571.1 - 0.032 13.6 0.1 0.081 12.3 0.1 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Pox_A28 PF04584.14 EGO55572.1 - 0.03 14.5 0.0 0.035 14.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A28 family DUF1917 PF08939.10 EGO55573.1 - 3.8e-46 158.1 0.0 5.9e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) IF4E PF01652.18 EGO55573.1 - 0.014 15.2 0.1 0.059 13.2 0.0 2.0 2 1 0 2 2 2 0 Eukaryotic initiation factor 4E SPOR PF05036.13 EGO55573.1 - 0.1 13.0 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Sporulation related domain WD40 PF00400.32 EGO55574.1 - 0.0087 16.9 0.0 3.3 8.7 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Xpo1 PF08389.12 EGO55575.1 - 3.6e-06 27.1 0.1 1.7e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 EGO55575.1 - 7.5e-05 22.6 0.0 0.00059 19.7 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain FAM176 PF14851.6 EGO55577.1 - 0.43 10.2 5.0 0.22 11.2 0.9 2.6 2 0 0 2 2 2 0 FAM176 family THUMP PF02926.17 EGO55578.1 - 3.9e-10 40.0 1.8 1.4e-08 35.0 0.2 2.5 2 0 0 2 2 2 2 THUMP domain SCAI PF12070.8 EGO55578.1 - 0.099 11.5 1.6 0.13 11.0 1.6 1.2 1 0 0 1 1 1 0 Protein SCAI NOA36 PF06524.12 EGO55581.1 - 1.4 8.1 6.0 2.4 7.4 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 EGO55581.1 - 2.2 8.7 4.7 5.2 7.5 4.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_C12 PF01088.21 EGO55582.1 - 2.3e-35 122.3 0.1 4.5e-32 111.5 0.0 2.6 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF3323 PF11796.8 EGO55582.1 - 0.16 11.8 3.8 0.07 13.0 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) tRNA-synt_2b PF00587.25 EGO55583.1 - 3.1e-33 115.3 0.1 2.7e-31 108.9 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGO55583.1 - 3.7e-20 71.9 0.4 8.3e-20 70.8 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EGO55583.1 - 1.5e-12 47.4 0.0 3.4e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EGO55583.1 - 2.8e-09 36.9 0.0 5.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain DUF3642 PF12182.8 EGO55583.1 - 0.13 12.5 0.5 0.55 10.6 0.3 2.0 2 0 0 2 2 2 0 Bacterial lipoprotein THOC2_N PF16134.5 EGO55583.1 - 0.38 9.3 1.8 0.73 8.4 1.8 1.3 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Transglut_core2 PF13369.6 EGO55584.1 - 3.1e-15 56.1 0.0 7.1e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 EGO55584.1 - 2.6e-10 40.7 0.0 1.4e-09 38.4 0.0 2.2 1 1 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box PF00646.33 EGO55584.1 - 9.9e-08 31.7 0.5 3.4e-07 30.0 0.5 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGO55584.1 - 1.4e-07 31.3 0.8 3e-07 30.2 0.8 1.6 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 EGO55584.1 - 0.0068 16.9 0.2 0.017 15.7 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Ytp1 PF10355.9 EGO55585.1 - 6.1e-121 402.9 6.7 9.2e-121 402.3 6.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EGO55585.1 - 9.8e-35 118.5 4.0 9.8e-35 118.5 4.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Peptidase_M15_4 PF13539.6 EGO55585.1 - 0.051 14.1 1.0 0.12 12.9 1.0 1.6 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Ca_hom_mod PF14798.6 EGO55585.1 - 0.12 11.5 0.6 0.32 10.1 0.0 1.8 2 0 0 2 2 2 0 Calcium homeostasis modulator TMEM252 PF15664.5 EGO55585.1 - 1.2 8.9 2.7 4.5 7.0 0.1 2.7 3 0 0 3 3 3 0 Transmembrane protein 252 family Lactamase_B PF00753.27 EGO55586.1 - 5.1e-19 69.1 4.5 7.1e-19 68.6 4.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 EGO55586.1 - 1.6e-15 56.8 0.0 3.6e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 EGO55586.1 - 6.1e-07 29.2 0.3 8.9e-07 28.6 0.3 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGO55586.1 - 0.042 13.7 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain UCH PF00443.29 EGO55587.1 - 1e-46 159.6 4.5 1.3e-46 159.2 4.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO55587.1 - 6.9e-31 108.0 8.9 1e-30 107.5 8.9 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGO55587.1 - 0.0019 18.5 0.2 0.0019 18.5 0.2 3.4 4 1 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein OrfB_Zn_ribbon PF07282.11 EGO55587.1 - 1.4 8.9 8.1 2.8 7.9 0.7 3.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Rubredoxin_2 PF18073.1 EGO55587.1 - 9.6 6.0 8.9 12 5.7 1.4 3.0 2 0 0 2 2 2 0 Rubredoxin metal binding domain PCI PF01399.27 EGO55588.1 - 9.3e-11 42.2 0.0 2.3e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 EGO55588.1 - 6e-07 28.9 3.0 1.2e-06 28.0 3.0 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix Dam PF05869.11 EGO55588.1 - 0.087 12.4 0.0 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 DNA N-6-adenine-methyltransferase (Dam) RIG-I_C-RD PF11648.8 EGO55588.1 - 0.14 12.4 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 C-terminal domain of RIG-I NmrA PF05368.13 EGO55589.1 - 3e-18 66.3 0.0 4.7e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO55589.1 - 8.2e-16 58.4 0.0 2e-15 57.2 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EGO55589.1 - 1.3e-13 51.0 0.0 2.6e-13 50.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO55589.1 - 6.8e-10 38.4 0.1 1.5e-09 37.3 0.1 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGO55589.1 - 7.8e-08 31.8 0.0 4.8e-06 25.9 0.0 2.6 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGO55589.1 - 1.6e-07 31.0 0.3 3.3e-07 30.0 0.1 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EGO55589.1 - 0.00015 21.3 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO55589.1 - 0.0019 18.1 0.0 0.53 10.2 0.0 3.3 4 0 0 4 4 4 1 KR domain Polysacc_synt_2 PF02719.15 EGO55589.1 - 0.0046 16.1 0.0 0.0082 15.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EGO55589.1 - 0.0069 15.6 0.1 1 8.5 0.0 3.3 2 1 1 3 3 3 1 Male sterility protein adh_short_C2 PF13561.6 EGO55589.1 - 0.009 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ApbA PF02558.16 EGO55589.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DapB_N PF01113.20 EGO55589.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus N6-adenineMlase PF10237.9 EGO55590.1 - 2.9e-55 186.5 0.3 3.7e-55 186.1 0.3 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 EGO55590.1 - 0.048 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Rhomboid PF01694.22 EGO55591.1 - 1.1e-13 51.4 12.3 1.1e-13 51.4 12.3 2.5 3 0 0 3 3 3 2 Rhomboid family Rsa3 PF14615.6 EGO55592.1 - 2.5e-21 74.9 0.6 3.1e-21 74.7 0.6 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 Glyco_hydro_28 PF00295.17 EGO55593.1 - 1.7e-98 329.7 12.7 2.1e-98 329.4 12.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase PF03211.13 EGO55593.1 - 0.00056 19.5 8.6 0.0046 16.5 5.2 2.4 2 0 0 2 2 2 2 Pectate lyase Gaa1 PF04114.14 EGO55594.1 - 3.2e-174 580.6 4.3 3.8e-174 580.4 4.3 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component DUF2070 PF09843.9 EGO55594.1 - 3 6.0 11.3 5.5 5.2 11.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HAD_SAK_1 PF10307.9 EGO55595.1 - 3.1e-76 255.7 0.0 4.4e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Aconitase PF00330.20 EGO55596.1 - 1.6e-150 502.2 0.0 2e-150 501.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGO55596.1 - 6.4e-44 149.5 0.0 1.3e-43 148.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.8 EGO55597.1 - 6.4e-10 39.1 0.9 1e-09 38.4 0.9 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGO55597.1 - 0.024 15.0 1.2 0.18 12.2 0.7 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) RTA1 PF04479.13 EGO55598.1 - 5.6e-51 173.1 1.5 8.2e-51 172.5 1.5 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF308 PF03729.13 EGO55598.1 - 0.025 14.9 2.5 0.19 12.0 0.8 2.4 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF3995 PF13160.6 EGO55598.1 - 0.095 13.1 2.6 0.81 10.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) CBM_5_12 PF02839.14 EGO55599.1 - 3.6 8.3 7.5 2.9 8.6 0.1 2.9 2 0 0 2 2 2 0 Carbohydrate binding domain FmdA_AmdA PF03069.15 EGO55600.1 - 9.3e-171 567.7 0.0 1.1e-170 567.4 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.11 EGO55601.1 - 8e-18 65.3 0.8 2.6e-15 57.1 0.8 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.7 EGO55602.1 - 2.4e-40 137.7 0.2 8.1e-40 136.0 0.0 2.0 3 0 0 3 3 3 1 Inheritance of peroxisomes protein 1 CBS PF00571.28 EGO55604.1 - 5.5e-20 71.6 2.4 6.2e-07 29.8 0.0 5.3 5 1 0 5 5 5 4 CBS domain Importin_rep_4 PF18808.1 EGO55605.1 - 9.8e-33 112.3 6.4 1.4e-31 108.6 1.2 4.3 4 1 1 5 5 4 1 Importin repeat Importin_rep_5 PF18816.1 EGO55605.1 - 1.4e-17 63.8 1.1 1.4e-17 63.8 1.1 3.1 3 0 0 3 3 3 1 Importin repeat HEAT PF02985.22 EGO55605.1 - 3.8e-17 60.9 23.0 0.0039 17.3 0.0 12.0 13 0 0 13 13 10 5 HEAT repeat HEAT_EZ PF13513.6 EGO55605.1 - 4.3e-16 59.0 25.9 1.7e-10 41.2 0.2 9.0 9 1 1 10 10 7 3 HEAT-like repeat HEAT_2 PF13646.6 EGO55605.1 - 2.7e-15 56.5 20.6 4.6e-06 26.9 0.0 8.5 4 2 2 8 8 7 3 HEAT repeats Importin_rep_6 PF18829.1 EGO55605.1 - 2.4e-13 50.2 0.4 5.4e-12 45.8 0.1 3.1 2 0 0 2 2 2 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 EGO55605.1 - 8e-13 48.8 0.4 0.0062 17.1 0.0 7.5 4 2 3 8 8 8 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EGO55605.1 - 1.4e-09 38.1 0.4 0.011 15.6 0.0 6.0 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) MMS19_C PF12460.8 EGO55605.1 - 5e-09 35.8 8.1 1.3e-07 31.1 0.4 4.1 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 EGO55605.1 - 6.5e-08 32.8 2.6 0.026 14.6 0.0 5.5 3 3 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 EGO55605.1 - 7.2e-08 32.4 0.5 0.0097 15.7 0.0 5.1 3 2 1 4 4 4 1 rRNA processing/ribosome biogenesis DRIM PF07539.12 EGO55605.1 - 1.4e-07 30.2 3.7 0.0013 17.1 0.4 4.0 3 1 1 4 4 4 2 Down-regulated in metastasis CLASP_N PF12348.8 EGO55605.1 - 6.4e-07 29.2 1.1 0.005 16.4 0.1 5.4 4 2 2 6 6 6 2 CLASP N terminal Adaptin_N PF01602.20 EGO55605.1 - 7e-05 21.6 7.4 0.005 15.5 0.9 3.4 3 1 0 3 3 3 2 Adaptin N terminal region Xpo1 PF08389.12 EGO55605.1 - 0.00019 21.6 0.5 0.0069 16.4 0.0 3.4 3 0 0 3 3 3 1 Exportin 1-like protein RTP1_C1 PF10363.9 EGO55605.1 - 0.00022 21.4 0.1 0.3 11.3 0.3 4.2 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 IBN_N PF03810.19 EGO55605.1 - 0.003 17.4 0.2 0.052 13.5 0.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain TFCD_C PF12612.8 EGO55605.1 - 0.0064 16.3 0.0 4.6 7.0 0.0 4.0 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal CAS_CSE1 PF03378.15 EGO55605.1 - 0.011 14.2 1.9 6.9 5.0 0.0 4.5 3 1 2 5 5 5 0 CAS/CSE protein, C-terminus DUF4042 PF13251.6 EGO55605.1 - 0.022 14.4 0.9 5.1 6.8 0.0 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF4042) Cnd3 PF12719.7 EGO55605.1 - 0.029 13.6 0.2 0.41 9.8 0.0 2.8 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Dopey_N PF04118.14 EGO55605.1 - 0.048 12.8 6.1 0.19 10.8 0.1 3.8 4 1 1 5 5 5 0 Dopey, N-terminal V-ATPase_H_N PF03224.14 EGO55605.1 - 0.054 12.8 4.9 0.39 10.0 0.1 3.5 2 1 0 2 2 2 0 V-ATPase subunit H Arm PF00514.23 EGO55605.1 - 0.11 12.6 11.0 2.5 8.3 0.0 5.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Herpes_UL3 PF03369.13 EGO55605.1 - 0.13 12.8 0.3 0.47 11.0 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus UL3 protein Telomere_reg-2 PF10193.9 EGO55605.1 - 7 7.1 9.2 2 8.9 1.5 3.9 3 2 2 5 5 4 0 Telomere length regulation protein PAS_9 PF13426.7 EGO55606.1 - 2e-26 92.2 0.1 1.8e-17 63.5 0.1 3.7 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 EGO55606.1 - 4.7e-22 78.1 1.5 3.7e-13 49.6 0.0 4.3 4 0 0 4 4 3 3 PAS fold GATA PF00320.27 EGO55606.1 - 5.6e-15 54.7 9.4 1.2e-14 53.6 9.4 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 EGO55606.1 - 4.4e-14 52.5 14.5 1.5e-05 24.9 0.0 5.6 5 1 0 5 5 5 3 PAS fold PAS_4 PF08448.10 EGO55606.1 - 1.2e-06 28.8 5.9 0.057 13.7 0.0 4.8 5 0 0 5 5 5 2 PAS fold PAS_2 PF08446.11 EGO55606.1 - 0.00013 22.6 0.0 0.81 10.4 0.0 3.8 3 0 0 3 3 3 1 PAS fold DDHD PF02862.17 EGO55606.1 - 0.0037 17.5 2.0 0.0037 17.5 2.0 2.8 2 1 0 2 2 1 1 DDHD domain TFIIA PF03153.13 EGO55606.1 - 0.0053 16.8 29.7 0.0053 16.8 29.7 3.4 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit EIIBC-GUT_N PF03612.14 EGO55606.1 - 0.63 9.8 17.3 2.1 8.0 11.7 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF719 PF05334.13 EGO55606.1 - 1.2 9.3 16.6 1.7 8.8 8.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF719) EPL1 PF10513.9 EGO55606.1 - 1.7 9.0 23.8 0.23 11.9 11.6 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like FYDLN_acid PF09538.10 EGO55606.1 - 3.5 8.3 7.8 4.7 7.9 3.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) eIF-3_zeta PF05091.12 EGO55606.1 - 9.3 5.1 28.4 1.6 7.6 17.8 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 EGO55607.1 - 0.0092 14.3 3.2 0.014 13.7 3.2 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Bromodomain PF00439.25 EGO55608.1 - 1.4e-38 130.8 0.1 6e-18 64.7 0.0 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 EGO55608.1 - 1.8e-19 69.8 0.8 5.2e-19 68.3 0.8 1.9 1 0 0 1 1 1 1 BAH domain CDC45 PF02724.14 EGO55608.1 - 0.00025 19.5 6.5 0.00025 19.5 6.5 3.1 3 0 0 3 3 3 1 CDC45-like protein CDC27 PF09507.10 EGO55608.1 - 0.21 11.0 37.4 0.23 10.8 6.4 3.6 3 0 0 3 3 3 0 DNA polymerase subunit Cdc27 OTU PF02338.19 EGO55609.1 - 3.4e-05 24.3 0.0 6.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease PB1 PF00564.24 EGO55609.1 - 0.094 12.7 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 PB1 domain Mito_carr PF00153.27 EGO55610.1 - 7.5e-46 154.0 5.9 1.9e-17 63.0 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Apt1 PF10351.9 EGO55610.1 - 0.014 14.2 1.3 0.02 13.8 1.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3774 PF12609.8 EGO55610.1 - 0.015 16.3 1.5 0.015 16.3 1.5 2.2 3 0 0 3 3 3 0 Wound-induced protein Sel1 PF08238.12 EGO55611.1 - 4.7e-17 62.0 29.2 1.1e-07 32.3 0.1 7.7 7 1 1 8 8 8 5 Sel1 repeat TPR_1 PF00515.28 EGO55611.1 - 0.0054 16.5 4.9 0.038 13.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGO55611.1 - 0.0066 16.5 8.4 0.39 10.9 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO55611.1 - 1.9 8.9 4.9 2 8.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO55611.1 - 6 7.7 6.1 8.7 7.2 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 EGO55612.1 - 2.8e-17 63.1 0.0 4.6e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EGO55612.1 - 0.19 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 SAC3/GANP family Coatomer_WDAD PF04053.14 EGO55613.1 - 1.3e-146 489.2 0.0 1.9e-146 488.6 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 EGO55613.1 - 1e-97 327.5 0.0 1.4e-97 327.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EGO55613.1 - 1.4e-38 130.2 16.1 1.8e-07 31.7 0.2 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO55613.1 - 4.6e-10 39.7 0.7 0.00019 21.7 0.0 5.5 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO55613.1 - 0.0052 15.5 7.0 0.9 8.1 0.1 3.9 3 1 1 4 4 4 2 Nucleoporin Nup120/160 IPPT PF01715.17 EGO55613.1 - 0.033 14.0 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 IPP transferase Glyco_transf_24 PF18404.1 EGO55614.1 - 4.8e-148 491.8 1.3 7.8e-148 491.1 1.3 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EGO55614.1 - 3.4e-67 227.1 0.1 3e-66 224.0 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 EGO55614.1 - 2.2e-59 201.0 0.2 1.3e-56 191.9 0.2 3.4 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EGO55614.1 - 1.2e-47 162.2 1.6 1.3e-47 162.2 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EGO55614.1 - 7.6e-46 155.4 0.1 6.3e-44 149.2 0.1 2.9 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EGO55614.1 - 3.3e-43 146.2 0.0 7e-43 145.2 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 EGO55614.1 - 3.3e-05 23.6 0.1 7e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Rad54_N PF08658.10 EGO55615.1 - 5.8e-60 202.6 2.2 3.3e-59 200.1 1.6 2.1 2 0 0 2 2 2 1 Rad54 N terminal SNF2_N PF00176.23 EGO55615.1 - 1.2e-57 195.2 0.0 2.1e-57 194.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO55615.1 - 1.1e-15 57.9 0.0 2.8e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO55615.1 - 7.7e-07 29.3 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGO55615.1 - 0.001 18.3 0.0 0.0037 16.5 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Sec7 PF01369.20 EGO55616.1 - 3.4e-28 98.6 0.3 9.3e-28 97.1 0.1 1.7 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 EGO55616.1 - 6.9e-19 68.4 0.0 1.7e-18 67.1 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain F-box-like PF12937.7 EGO55617.1 - 0.00014 21.7 0.3 0.00038 20.3 0.3 1.8 1 0 0 1 1 1 1 F-box-like DUF1383 PF07134.11 EGO55617.1 - 0.058 12.5 0.0 0.085 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1383) Glyco_hydro_61 PF03443.14 EGO55619.1 - 2.6e-55 187.6 0.0 3.3e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Alpha-L-AF_C PF06964.12 EGO55620.1 - 1.4e-17 64.4 0.0 3.1e-17 63.2 0.0 1.5 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain Mrx7 PF10906.8 EGO55621.1 - 5.1e-09 36.3 0.1 6.6e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 MIOREX complex component 7 DUF1996 PF09362.10 EGO55623.1 - 1.2e-80 270.9 0.2 1.5e-80 270.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) zf-C4_ClpX PF06689.13 EGO55625.1 - 0.008 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 ClpX C4-type zinc finger LZ3wCH PF18517.1 EGO55625.1 - 0.035 14.2 0.2 1.9 8.7 0.0 2.9 3 0 0 3 3 3 0 Leucine zipper with capping helix domain DUF2789 PF10982.8 EGO55625.1 - 0.061 13.5 0.1 2.2 8.5 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2789) NPP1 PF05630.11 EGO55626.1 - 2.4e-60 204.0 0.2 2.8e-60 203.8 0.2 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Mito_carr PF00153.27 EGO55627.1 - 4.9e-16 58.4 1.0 1.9e-10 40.5 0.1 3.3 2 1 0 2 2 2 2 Mitochondrial carrier protein DUF919 PF06034.11 EGO55627.1 - 0.034 14.0 1.0 0.074 12.9 1.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Glyco_transf_90 PF05686.12 EGO55628.1 - 1.5e-14 53.8 7.1 3.5e-12 46.0 2.7 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 Defensin_4 PF07936.12 EGO55628.1 - 0.12 12.3 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Potassium-channel blocking toxin MARVEL PF01284.23 EGO55629.1 - 2.6e-07 30.8 16.1 4.3e-07 30.1 16.0 1.4 1 1 0 1 1 1 1 Membrane-associating domain CCSMST1 PF15013.6 EGO55629.1 - 4.7 7.5 11.2 0.93 9.7 2.3 2.5 2 0 0 2 2 2 0 CCSMST1 family Arginase PF00491.21 EGO55630.1 - 2e-76 257.2 0.1 2.3e-76 256.9 0.1 1.0 1 0 0 1 1 1 1 Arginase family Cnn_1N PF07989.11 EGO55631.1 - 6.2e-22 77.5 7.9 9e-22 77.0 8.7 11.5 8 3 2 10 10 10 2 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 EGO55631.1 - 1.5e-08 34.8 13.3 1.5e-08 34.8 13.3 12.5 13 2 1 14 14 14 1 Micro-tubular organiser Mto1 C-term Mto2-binding region RrnaAD PF00398.20 EGO55631.1 - 9.5e-07 28.1 0.0 2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NPV_P10 PF05531.12 EGO55631.1 - 0.14 12.6 0.1 0.14 12.6 0.1 4.9 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1993 PF09351.10 EGO55634.1 - 9.6e-51 172.1 0.7 1.1e-50 171.9 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Methyltransf_2 PF00891.18 EGO55635.1 - 4.8e-22 78.3 0.0 1.1e-21 77.1 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain FeoC PF09012.10 EGO55635.1 - 0.059 13.5 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator Glyco_hydro_61 PF03443.14 EGO55637.1 - 1.8e-08 34.5 0.1 2.4e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HMG_box PF00505.19 EGO55638.1 - 1.2e-07 32.0 0.1 9.5e-07 29.1 0.1 2.3 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO55638.1 - 0.041 14.5 0.0 0.097 13.3 0.0 1.7 1 0 0 1 1 1 0 HMG-box domain GMP_synt_C PF00958.22 EGO55639.1 - 1.8e-40 136.9 0.0 3.4e-40 136.0 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EGO55639.1 - 1.9e-38 132.2 0.0 3.2e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EGO55639.1 - 6.9e-10 38.4 0.0 5.4e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EGO55639.1 - 4.5e-07 29.8 0.0 1.1e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 Arginosuc_synth PF00764.19 EGO55639.1 - 0.00094 18.6 0.1 0.0014 18.0 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase tRNA_Me_trans PF03054.16 EGO55639.1 - 0.0012 17.7 0.0 0.0035 16.2 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 EGO55639.1 - 0.014 15.0 0.0 0.08 12.5 0.0 2.0 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 EGO55639.1 - 0.027 14.0 0.0 0.34 10.4 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 EGO55639.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family DUF2501 PF10696.9 EGO55639.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2501) zf-C2H2_4 PF13894.6 EGO55641.1 - 1.7e-07 31.5 26.2 0.073 13.9 0.3 5.7 4 1 1 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO55641.1 - 2.6e-06 27.6 18.1 0.052 14.0 0.3 5.2 3 1 1 4 4 4 2 Zinc finger, C2H2 type TF_Zn_Ribbon PF08271.12 EGO55641.1 - 0.0017 17.9 0.2 0.013 15.0 0.0 2.5 2 0 0 2 2 2 1 TFIIB zinc-binding zf-met PF12874.7 EGO55641.1 - 0.013 15.8 9.5 4.6 7.8 0.3 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type PAT1 PF09770.9 EGO55641.1 - 0.026 12.8 0.7 0.037 12.3 0.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-ribbon_3 PF13248.6 EGO55641.1 - 0.17 11.4 2.3 5.5 6.5 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Elf1 PF05129.13 EGO55641.1 - 0.6 10.2 6.3 2.7 8.1 0.0 2.9 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like Zn_ribbon_SprT PF17283.2 EGO55641.1 - 0.96 9.4 8.6 2 8.4 5.1 2.8 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-C2H2_jaz PF12171.8 EGO55641.1 - 0.97 9.8 8.4 1.1 9.6 0.2 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EGO55641.1 - 1.8 8.9 16.3 8.1 6.8 0.1 4.8 4 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.6 EGO55641.1 - 8 7.1 9.1 61 4.2 4.8 3.0 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-BED PF02892.15 EGO55641.1 - 8.5 6.5 10.5 1e+02 3.0 8.0 3.6 2 1 0 2 2 2 0 BED zinc finger PMI_typeI PF01238.21 EGO55642.1 - 5.8e-73 246.2 0.0 8.7e-72 242.4 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 EGO55642.1 - 6.9e-06 26.0 0.0 0.00042 20.2 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 EGO55642.1 - 1e-05 25.1 0.0 0.15 11.8 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EGO55642.1 - 0.0024 17.5 1.7 0.014 15.1 0.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF861) AraC_N PF06719.13 EGO55642.1 - 0.047 13.3 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 AraC-type transcriptional regulator N-terminus DUF3292 PF11696.8 EGO55643.1 - 1.4e-261 869.6 0.0 4.8e-151 504.3 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) ERAP1_C PF11838.8 EGO55645.1 - 6.1e-82 275.7 0.0 1.5e-80 271.1 0.0 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EGO55645.1 - 5.7e-81 271.2 2.4 9.5e-81 270.5 2.4 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EGO55645.1 - 6.8e-45 153.5 0.1 1.3e-43 149.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF45 PF01863.17 EGO55645.1 - 0.0024 18.0 0.0 0.0079 16.3 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function DUF45 Peptidase_M50 PF02163.22 EGO55645.1 - 0.08 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M50 SprT-like PF10263.9 EGO55645.1 - 0.12 12.3 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 SprT-like family TFIIA PF03153.13 EGO55646.1 - 0.53 10.2 35.7 0.069 13.1 19.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 EGO55646.1 - 7.1 5.9 5.8 13 5.1 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dabb PF07876.12 EGO55647.1 - 6.4e-24 84.4 0.0 7.1e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF2277 PF10041.9 EGO55647.1 - 0.11 12.8 0.0 3.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) MMPL PF03176.15 EGO55648.1 - 0.96 8.3 3.5 1.6 7.6 3.5 1.3 1 0 0 1 1 1 0 MMPL family Hamartin PF04388.12 EGO55648.1 - 2.6 6.6 7.0 3 6.4 7.0 1.2 1 0 0 1 1 1 0 Hamartin protein JAKMIP_CC3 PF16034.5 EGO55648.1 - 4.4 7.2 4.8 2.7 7.9 1.6 2.0 1 1 1 2 2 2 0 JAKMIP CC3 domain Myb_DNA-binding PF00249.31 EGO55649.1 - 1.4e-18 66.8 9.3 1.2e-08 35.0 0.1 4.6 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO55649.1 - 3.6e-13 49.6 13.8 1.2e-08 35.0 0.2 4.2 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGO55649.1 - 0.016 15.6 12.6 0.13 12.7 4.4 4.1 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 EGO55649.1 - 0.27 11.6 7.5 0.39 11.0 1.3 3.7 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like zf-CCHC PF00098.23 EGO55652.1 - 1.2e-07 31.5 2.2 2.3e-07 30.6 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGO55652.1 - 0.28 10.9 1.0 0.55 10.0 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle GREB1 PF15782.5 EGO55653.1 - 0.052 10.7 8.7 0.064 10.4 8.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AAA_16 PF13191.6 EGO55654.1 - 2.1e-08 34.7 0.2 6.3e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 EGO55654.1 - 0.089 12.3 0.1 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 EGO55654.1 - 0.11 11.6 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Fungal_trans_2 PF11951.8 EGO55657.1 - 3.8e-31 108.3 0.5 1.4e-16 60.3 0.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO55657.1 - 2.1e-08 34.2 11.5 3.5e-08 33.4 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 EGO55657.1 - 1.7 8.8 8.5 4.8 7.4 8.5 1.8 1 0 0 1 1 1 0 AT hook motif polyprenyl_synt PF00348.17 EGO55659.1 - 4e-74 248.9 0.0 7.6e-74 248.0 0.0 1.4 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 EGO55659.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Vma12 PF11712.8 EGO55660.1 - 3e-45 153.7 0.0 4.1e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2746 PF10874.8 EGO55660.1 - 0.34 11.3 1.1 15 6.1 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2746) PBP_N PF17093.5 EGO55660.1 - 0.91 9.8 4.4 1.7 8.9 0.2 2.3 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus zf-C2H2_3 PF13878.6 EGO55661.1 - 2.8e-09 36.6 0.2 5.5e-09 35.7 0.2 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO PSDC PF12588.8 EGO55662.1 - 2.9e-54 182.9 0.0 4.4e-54 182.3 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EGO55662.1 - 5.3e-37 127.3 0.0 1.6e-36 125.7 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 EGO55662.1 - 0.00058 19.6 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 2 Biotin-lipoyl like PTS_EIIA_1 PF00358.20 EGO55662.1 - 0.039 13.7 0.1 0.29 10.9 0.1 2.1 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Biotin_lipoyl PF00364.22 EGO55662.1 - 0.076 12.9 0.0 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 Biotin-requiring enzyme Peptidase_M23 PF01551.22 EGO55662.1 - 0.093 13.0 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M23 DUF5617 PF18493.1 EGO55662.1 - 0.18 11.9 0.3 0.38 10.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) ADH_N_2 PF16884.5 EGO55665.1 - 2.3e-26 91.8 0.0 4.4e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EGO55665.1 - 3.1e-23 82.2 0.0 4.9e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO55665.1 - 5.2e-08 34.0 0.0 9.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PhoH PF02562.16 EGO55665.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Amidohydro_1 PF01979.20 EGO55668.1 - 3.5e-25 89.1 0.0 2.3e-16 60.0 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EGO55668.1 - 5.9e-13 49.1 0.1 9.9e-07 28.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family AalphaY_MDB PF04611.12 EGO55668.1 - 0.15 12.0 0.3 0.34 10.9 0.1 1.5 2 0 0 2 2 2 0 Mating type protein A alpha Y mating type dependent binding region PIP5K PF01504.18 EGO55669.1 - 5.2e-103 344.0 0.1 8.9e-103 343.3 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SYS1 PF09801.9 EGO55670.1 - 3.4e-51 173.2 2.1 4e-51 173.0 2.1 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF3792 PF12670.7 EGO55670.1 - 0.38 10.9 6.7 1.2 9.3 4.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) COX6B PF02297.17 EGO55671.1 - 2.5e-23 82.1 6.2 3.1e-23 81.8 6.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Acyl-CoA_dh_1 PF00441.24 EGO55673.1 - 6.1e-25 88.2 0.2 9.3e-25 87.6 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGO55673.1 - 3.1e-24 85.8 0.0 6e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGO55673.1 - 1.1e-17 63.9 0.0 2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGO55673.1 - 5.2e-07 30.0 0.1 9.6e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MTHFR_C PF12225.8 EGO55674.1 - 0.15 11.7 8.3 0.19 11.4 8.3 1.3 1 0 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal zf_UBZ PF18439.1 EGO55674.1 - 0.31 10.7 3.6 0.55 9.9 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-LITAF-like PF10601.9 EGO55674.1 - 0.84 9.9 4.7 2.9 8.2 0.6 2.2 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zf-C2HC5 PF06221.13 EGO55674.1 - 2.1 8.4 8.0 6.2 6.9 1.9 2.2 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type OrfB_Zn_ribbon PF07282.11 EGO55674.1 - 9.5 6.2 14.7 0.97 9.4 2.7 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain UQ_con PF00179.26 EGO55675.1 - 6.3e-53 178.2 0.0 7.1e-53 178.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO55675.1 - 0.0028 17.4 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGO55675.1 - 0.0061 16.8 0.0 0.0074 16.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 EGO55675.1 - 0.022 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain NAD_binding_6 PF08030.12 EGO55676.1 - 3e-31 108.7 0.0 5.9e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGO55676.1 - 2.1e-21 76.1 1.0 4e-21 75.1 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 EGO55676.1 - 2.9e-18 66.2 20.0 7.6e-18 64.8 12.7 2.5 1 1 1 2 2 2 2 Ferric reductase like transmembrane component DUF2017 PF09438.10 EGO55676.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) XPG_I PF00867.18 EGO55677.1 - 2.7e-32 111.0 1.9 3.5e-32 110.6 0.0 2.1 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EGO55677.1 - 2.4e-26 92.1 0.1 2.4e-26 92.1 0.1 2.0 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EGO55677.1 - 1.4e-05 25.5 0.7 0.00019 22.0 0.0 2.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold BLM_N PF16202.5 EGO55677.1 - 0.019 14.1 3.0 0.033 13.3 3.0 1.3 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein HHH_5 PF14520.6 EGO55677.1 - 0.072 13.7 0.0 0.21 12.2 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain F1F0-ATPsyn_F PF10791.9 EGO55677.1 - 0.17 12.4 0.1 32 5.1 0.3 2.5 2 0 0 2 2 2 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi Acyl-CoA_dh_1 PF00441.24 EGO55678.1 - 1.7e-43 148.4 0.2 2.5e-43 147.9 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGO55678.1 - 1.9e-22 79.3 0.0 3.1e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 EGO55678.1 - 3.4e-20 72.0 0.2 6.6e-20 71.0 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 EGO55678.1 - 4.8e-17 62.6 0.0 1.1e-16 61.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGO55678.1 - 2.2e-09 37.7 0.0 3.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF5525 PF17663.1 EGO55678.1 - 0.012 13.7 3.4 0.019 13.1 3.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5525) Ribosomal_60s PF00428.19 EGO55678.1 - 0.45 11.1 4.3 0.93 10.1 4.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein CAP_N PF01213.19 EGO55678.1 - 2 7.8 5.4 2.9 7.3 5.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RRM_1 PF00076.22 EGO55679.1 - 1.2e-07 31.4 0.0 2.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGO55679.1 - 0.081 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GNAT_acetyltr_2 PF13718.6 EGO55680.1 - 1.8e-95 318.7 0.0 3.8e-95 317.6 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EGO55680.1 - 7.7e-93 310.5 0.0 1.6e-92 309.5 0.0 1.6 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EGO55680.1 - 1.6e-65 220.3 0.0 8.1e-65 218.0 0.0 2.2 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 EGO55680.1 - 2e-34 117.4 0.0 5e-34 116.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 EGO55680.1 - 0.0012 18.5 0.2 0.098 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGO55680.1 - 0.0016 18.7 0.1 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta2 PF13177.6 EGO55680.1 - 0.034 13.9 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Pkinase PF00069.25 EGO55682.1 - 1.8e-72 243.9 0.0 2.1e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO55682.1 - 1.7e-29 102.9 0.0 2.3e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO55682.1 - 4.1e-07 29.6 0.0 5.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGO55682.1 - 0.00017 20.5 0.0 0.00028 19.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGO55682.1 - 0.00068 19.6 0.1 0.0011 19.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGO55682.1 - 0.00079 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAP2_3 PF14378.6 EGO55683.1 - 1.1e-24 87.2 13.0 1.1e-24 87.2 13.0 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EGO55683.1 - 2.9e-09 36.8 4.2 2.9e-09 36.8 4.2 2.1 2 1 0 2 2 2 1 PAP2 superfamily UCH PF00443.29 EGO55684.1 - 5.9e-29 101.3 0.0 1.2e-28 100.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 EGO55684.1 - 3.3e-12 46.1 0.5 4.7e-07 29.6 0.1 2.9 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.6 EGO55684.1 - 1.4e-08 34.7 0.0 0.00064 19.4 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.10 EGO55684.1 - 0.00056 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 PUB domain Kelch_1 PF01344.25 EGO55684.1 - 0.1 12.2 0.2 0.23 11.1 0.2 1.5 1 0 0 1 1 1 0 Kelch motif Tim17 PF02466.19 EGO55685.1 - 1.9e-07 31.5 8.3 3e-07 30.8 8.3 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UPF0220 PF05255.11 EGO55685.1 - 1 8.9 3.6 3.1 7.3 3.6 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0220) LETM1 PF07766.13 EGO55686.1 - 5.5e-08 32.5 0.1 1.5e-06 27.8 0.0 2.5 1 1 1 3 3 3 1 LETM1-like protein DUF4355 PF14265.6 EGO55686.1 - 9.3 6.5 11.6 4.5 7.5 5.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) Ribonuc_L-PSP PF01042.21 EGO55687.1 - 8.7e-41 138.7 0.0 9.8e-41 138.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ferric_reduct PF01794.19 EGO55688.1 - 6.1e-22 78.1 10.1 6.1e-22 78.1 10.1 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGO55688.1 - 5e-17 62.5 0.0 7.8e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGO55688.1 - 1.5e-07 31.5 0.0 0.0017 18.5 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 EGO55688.1 - 1e-06 29.3 0.1 0.013 16.2 0.0 3.1 2 1 1 3 3 3 2 Oxidoreductase NAD-binding domain VacA2 PF03077.14 EGO55688.1 - 0.41 10.5 1.9 0.79 9.6 1.9 1.4 1 0 0 1 1 1 0 Putative vacuolating cytotoxin VanZ PF04892.12 EGO55689.1 - 1.2e-07 32.4 1.3 1.7e-07 31.9 1.3 1.2 1 0 0 1 1 1 1 VanZ like family Bromodomain PF00439.25 EGO55690.1 - 8.8e-18 64.2 0.2 2.4e-17 62.8 0.2 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 EGO55690.1 - 9.8e-09 35.1 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated SHMT PF00464.19 EGO55693.1 - 1.1e-212 705.9 0.0 1.3e-212 705.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.19 EGO55693.1 - 6.6e-05 22.0 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGO55693.1 - 9.6e-05 21.7 0.0 0.00033 19.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGO55693.1 - 0.011 14.3 0.0 0.019 13.5 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF4142 PF13628.6 EGO55693.1 - 0.078 13.2 0.3 0.17 12.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) KKLCAg1 PF15204.6 EGO55693.1 - 0.17 12.0 0.1 0.51 10.5 0.0 1.8 2 0 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 Asp PF00026.23 EGO55694.1 - 8.9e-108 360.4 0.2 1.1e-107 360.2 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO55694.1 - 5.1e-16 59.4 1.3 6.3e-14 52.6 0.6 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO55694.1 - 7.6e-05 23.3 0.1 1.5 9.5 0.0 3.4 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EGO55694.1 - 0.0013 19.2 0.0 2.1 8.9 0.0 2.8 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EGO55694.1 - 0.014 15.1 0.0 0.23 11.2 0.0 2.6 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal DUF155 PF02582.14 EGO55696.1 - 3.2e-50 170.7 0.0 7e-50 169.6 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Cupin_1 PF00190.22 EGO55696.1 - 0.022 14.3 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Cupin Bclx_interact PF08945.10 EGO55696.1 - 0.3 10.9 1.9 0.35 10.7 0.2 2.0 2 0 0 2 2 2 0 Bcl-x interacting, BH3 domain RINT1_TIP1 PF04437.13 EGO55697.1 - 1e-183 611.8 0.0 1.8e-183 611.0 0.0 1.4 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DHR10 PF18595.1 EGO55697.1 - 0.0001 22.4 10.1 0.00034 20.7 5.3 2.9 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain COG2 PF06148.11 EGO55697.1 - 0.00083 19.4 5.2 0.0037 17.4 3.0 3.1 2 1 1 3 3 2 1 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.12 EGO55697.1 - 0.0056 16.7 4.3 0.0056 16.7 4.3 2.8 3 0 0 3 3 2 1 TPR/MLP1/MLP2-like protein ADIP PF11559.8 EGO55697.1 - 0.019 15.1 6.7 0.063 13.4 6.2 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.8 EGO55697.1 - 0.056 11.0 10.0 0.083 10.4 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4164 PF13747.6 EGO55697.1 - 0.075 13.3 13.4 0.03 14.6 5.8 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) DUF1664 PF07889.12 EGO55697.1 - 0.11 12.5 2.6 0.31 11.1 1.7 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EGO55697.1 - 0.12 12.7 1.7 0.48 10.8 1.7 2.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.11 EGO55697.1 - 0.4 10.5 6.4 0.073 12.9 1.4 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 DSBA PF01323.20 EGO55697.1 - 0.53 10.0 2.6 0.57 9.9 0.9 1.9 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Nsp1_C PF05064.13 EGO55697.1 - 0.76 9.6 5.9 3.4 7.5 2.1 3.2 2 1 1 3 3 3 0 Nsp1-like C-terminal region CRISPR_Cse2 PF09485.10 EGO55697.1 - 1.4 9.4 11.6 0.74 10.3 7.5 2.4 1 1 1 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) OmpH PF03938.14 EGO55697.1 - 2 8.8 9.4 0.79 10.1 4.7 2.7 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) T3SS_needle_E PF08988.10 EGO55697.1 - 3.9 7.7 10.4 4.6 7.5 6.9 3.0 1 1 1 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Sec34 PF04136.15 EGO55698.1 - 1.2e-49 168.0 0.6 2.7e-49 166.9 0.6 1.6 1 0 0 1 1 1 1 Sec34-like family SKA2 PF16740.5 EGO55698.1 - 0.039 13.8 0.1 0.16 11.7 0.1 2.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 GCIP PF13324.6 EGO55698.1 - 0.097 12.3 1.9 0.26 10.9 0.9 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Ribosomal_L32p PF01783.23 EGO55698.1 - 0.5 10.7 2.1 1.3 9.4 0.1 2.2 2 0 0 2 2 2 0 Ribosomal L32p protein family RCC1 PF00415.18 EGO55699.1 - 1.4e-30 105.6 9.3 4e-08 33.7 0.0 7.7 6 1 1 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGO55699.1 - 1.9e-18 65.7 14.6 1.1e-11 44.2 0.0 6.5 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat FRQ PF09421.10 EGO55701.1 - 0 1341.5 39.7 0 1341.2 39.7 1.0 1 0 0 1 1 1 1 Frequency clock protein Prefoldin PF02996.17 EGO55702.1 - 1.7e-35 121.6 0.3 2.7e-35 120.9 0.3 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EGO55702.1 - 0.014 15.4 0.2 0.014 15.4 0.2 2.9 2 1 1 3 3 3 0 Prefoldin subunit CLZ PF16526.5 EGO55702.1 - 0.04 14.3 5.8 2.7 8.4 0.6 2.7 2 2 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BCAS3 PF12490.8 EGO55702.1 - 0.044 13.3 0.9 0.065 12.7 0.9 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 End3 PF12761.7 EGO55702.1 - 0.33 11.1 5.8 0.075 13.2 1.0 2.3 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Lebercilin PF15619.6 EGO55702.1 - 0.39 10.4 7.7 3.9 7.1 4.0 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ThiD2 PF17792.1 EGO55702.1 - 0.46 11.0 4.3 7.4 7.1 0.2 2.1 2 0 0 2 2 2 0 ThiD2 family KLRAQ PF10205.9 EGO55702.1 - 1.8 8.9 8.0 1.3 9.3 0.3 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein CRAL_TRIO PF00650.20 EGO55703.1 - 4.3e-37 127.3 0.0 6.8e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGO55703.1 - 1.4e-07 31.6 1.2 2.9e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGO55703.1 - 0.015 15.5 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF1769 PF08588.10 EGO55703.1 - 0.098 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Mis14 PF08641.12 EGO55704.1 - 2.1e-11 44.3 13.0 1e-09 38.8 3.8 4.1 4 0 0 4 4 4 1 Kinetochore protein Mis14 like Menin PF05053.13 EGO55704.1 - 0.0018 16.7 3.5 0.0018 16.7 3.5 2.0 2 0 0 2 2 2 2 Menin Coilin_N PF15862.5 EGO55704.1 - 0.006 16.4 3.7 0.012 15.5 3.7 1.5 1 0 0 1 1 1 1 Coilin N-terminus Hamartin PF04388.12 EGO55704.1 - 0.36 9.4 7.1 0.47 9.1 7.1 1.1 1 0 0 1 1 1 0 Hamartin protein Tim54 PF11711.8 EGO55704.1 - 1.2 7.9 6.7 2.1 7.0 6.7 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TMEM214 PF10151.9 EGO55704.1 - 1.5 7.2 7.7 2 6.8 7.7 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Pannexin_like PF12534.8 EGO55704.1 - 2.5 7.1 4.7 3.7 6.5 4.7 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 ALMT PF11744.8 EGO55704.1 - 4 6.2 7.4 6.3 5.5 7.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 EGO55704.1 - 9.9 4.8 7.5 13 4.4 7.5 1.1 1 0 0 1 1 1 0 Presenilin PAP1 PF08601.10 EGO55705.1 - 0.37 10.5 5.7 0.46 10.1 5.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 AAA PF00004.29 EGO55706.1 - 2.2e-45 154.3 0.1 6.5e-45 152.8 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGO55706.1 - 1.7e-10 40.7 0.1 1e-09 38.2 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EGO55706.1 - 1.9e-08 34.4 0.1 6.6e-08 32.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGO55706.1 - 5.4e-08 33.1 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGO55706.1 - 1.6e-07 31.8 0.1 3.7e-05 24.2 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EGO55706.1 - 3.4e-06 26.4 0.0 7e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EGO55706.1 - 3.6e-05 24.1 0.9 0.0088 16.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EGO55706.1 - 0.00024 20.9 0.0 0.00073 19.3 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGO55706.1 - 0.00044 20.8 0.0 0.0013 19.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 EGO55706.1 - 0.00051 19.8 0.1 0.0012 18.6 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_28 PF13521.6 EGO55706.1 - 0.0007 19.9 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGO55706.1 - 0.00089 18.8 0.1 0.0032 17.0 0.1 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EGO55706.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 EGO55706.1 - 0.0014 18.6 0.0 0.019 15.0 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGO55706.1 - 0.0018 18.6 0.0 0.0046 17.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 EGO55706.1 - 0.0019 18.3 0.1 0.0078 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EGO55706.1 - 0.0023 17.9 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 EGO55706.1 - 0.0044 16.8 0.6 0.013 15.2 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 EGO55706.1 - 0.0057 16.5 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EGO55706.1 - 0.0072 16.3 0.2 0.12 12.3 0.0 2.6 2 1 1 3 3 2 1 NACHT domain Mg_chelatase PF01078.21 EGO55706.1 - 0.0072 15.7 0.2 0.016 14.6 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGO55706.1 - 0.0073 16.1 0.1 0.03 14.0 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 EGO55706.1 - 0.0084 16.3 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_Hsp90 PF03225.14 EGO55706.1 - 0.01 14.4 0.0 0.015 13.8 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue TniB PF05621.11 EGO55706.1 - 0.013 14.9 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 EGO55706.1 - 0.021 14.6 0.2 0.055 13.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 EGO55706.1 - 0.033 13.1 0.0 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase Bac_DnaA PF00308.18 EGO55706.1 - 0.04 13.8 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase_2 PF01637.18 EGO55706.1 - 0.04 13.8 1.0 0.34 10.8 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea ATPase PF06745.13 EGO55706.1 - 0.042 13.2 1.4 0.56 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.6 EGO55706.1 - 0.043 13.6 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGO55706.1 - 0.067 12.8 1.1 0.22 11.1 0.1 2.2 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.26 EGO55706.1 - 0.069 12.9 0.2 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.6 EGO55706.1 - 0.07 13.6 0.5 6.9 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGO55706.1 - 0.084 12.1 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 EGO55706.1 - 0.12 12.7 0.1 0.37 11.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGO55706.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 EGO55706.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 EGO55706.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Folliculin PF11704.8 EGO55707.1 - 2.3e-62 210.2 0.0 5.7e-62 208.9 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Y_phosphatase PF00102.27 EGO55709.1 - 1.4e-46 159.0 0.0 9.9e-36 123.5 0.0 3.1 2 1 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGO55709.1 - 0.00044 20.4 0.0 0.00095 19.3 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 EGO55709.1 - 0.0025 17.6 0.0 0.0064 16.3 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGO55709.1 - 0.021 14.8 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DNA_pol_A_exo1 PF01612.20 EGO55710.1 - 1.1e-40 139.2 0.1 1.8e-40 138.5 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EGO55710.1 - 7.6e-27 93.9 0.1 7.6e-27 93.9 0.1 2.4 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 EGO55710.1 - 1.1e-13 51.0 0.0 2.3e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Nop14 PF04147.12 EGO55710.1 - 1.2 7.2 37.6 2.2 6.4 37.6 1.4 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 EGO55710.1 - 1.7 8.7 45.5 3.9 7.5 45.5 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Mitofilin PF09731.9 EGO55710.1 - 1.8 7.3 35.8 2.9 6.6 35.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Borrelia_P83 PF05262.11 EGO55710.1 - 1.9 6.9 29.1 3.1 6.2 29.1 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Nop53 PF07767.11 EGO55710.1 - 3.6 6.9 52.5 8 5.7 52.5 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Gpi1 PF05024.15 EGO55711.1 - 4.7e-78 261.6 7.3 8.6e-78 260.7 7.3 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) UPF0203 PF05254.12 EGO55711.1 - 6e-24 84.1 5.0 1.3e-23 83.0 5.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) 7tm_1 PF00001.21 EGO55711.1 - 0.004 16.5 0.4 0.0084 15.5 0.4 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) COX17 PF05051.13 EGO55711.1 - 0.011 16.0 0.5 0.028 14.8 0.5 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 EGO55711.1 - 1.5 8.9 4.6 2.1 8.4 1.0 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like TBCC PF07986.12 EGO55712.1 - 1.4e-28 99.1 0.0 2.3e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EGO55712.1 - 1.1e-09 38.7 0.3 2.3e-09 37.7 0.3 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain T4SS PF07996.11 EGO55712.1 - 0.0012 19.3 2.4 0.54 10.6 0.1 2.2 1 1 1 2 2 2 2 Type IV secretion system proteins HisKA_3 PF07730.13 EGO55712.1 - 0.032 14.8 0.1 0.093 13.3 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase Cytochrom_B562 PF07361.11 EGO55712.1 - 0.083 13.6 0.4 0.27 11.9 0.2 1.9 1 1 1 2 2 2 0 Cytochrome b562 Dmrt1 PF12374.8 EGO55712.1 - 0.11 12.9 0.4 0.32 11.5 0.4 1.7 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 Neugrin PF06413.11 EGO55712.1 - 2.7 8.0 5.9 13 5.7 0.3 2.5 2 1 0 2 2 2 0 Neugrin Med9 PF07544.13 EGO55713.1 - 1.3e-11 44.4 0.0 2.3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 TFIIF_alpha PF05793.12 EGO55713.1 - 0.35 9.4 1.0 0.41 9.2 1.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) iPGM_N PF06415.13 EGO55714.1 - 3.1e-79 265.4 0.0 4.2e-79 265.0 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EGO55714.1 - 7.4e-66 222.0 0.0 8.5e-66 221.8 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EGO55714.1 - 6.1e-07 29.1 0.0 2.5e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGO55714.1 - 0.00035 20.3 0.0 0.00068 19.3 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase AP_endonuc_2 PF01261.24 EGO55714.1 - 0.051 13.0 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel ATP-synt_C PF00137.21 EGO55716.1 - 1.6e-10 41.2 12.5 1.6e-10 41.2 12.5 2.0 2 0 0 2 2 2 1 ATP synthase subunit C MOZ_SAS PF01853.18 EGO55717.1 - 5e-55 185.9 0.0 7.3e-55 185.4 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EGO55717.1 - 2.9e-08 33.2 3.1 0.0076 15.8 2.9 2.3 2 0 0 2 2 2 2 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EGO55717.1 - 0.027 14.9 0.0 0.26 11.7 0.0 2.4 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain TFIIA PF03153.13 EGO55717.1 - 0.39 10.7 14.3 0.56 10.2 14.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_methylase PF00145.17 EGO55719.1 - 1.3e-29 103.6 0.0 2.7e-25 89.4 0.0 2.4 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase BAH PF01426.18 EGO55719.1 - 4e-08 33.2 0.4 0.0036 17.1 0.0 3.0 3 0 0 3 3 3 2 BAH domain Pkinase PF00069.25 EGO55721.1 - 3.4e-66 223.3 0.0 4.8e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO55721.1 - 8.4e-42 143.2 0.0 1.2e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO55721.1 - 2.3e-07 30.5 0.0 8.3e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGO55721.1 - 4e-05 22.7 0.2 4e-05 22.7 0.2 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EGO55721.1 - 0.029 13.7 0.0 0.071 12.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AMP-binding PF00501.28 EGO55721.1 - 0.11 11.1 0.1 0.2 10.2 0.1 1.3 1 0 0 1 1 1 0 AMP-binding enzyme Ferlin_C PF16165.5 EGO55721.1 - 0.19 11.7 0.3 0.64 9.9 0.3 2.0 1 0 0 1 1 1 0 Ferlin C-terminus APH PF01636.23 EGO55721.1 - 0.63 9.9 3.4 0.88 9.4 0.2 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family C2 PF00168.30 EGO55722.1 - 7e-12 45.5 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain DUF755 PF05501.11 EGO55722.1 - 2.7 8.3 11.0 11 6.4 1.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DUF2681 PF10883.8 EGO55723.1 - 0.015 15.7 0.1 0.015 15.7 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) Rax2 PF12768.7 EGO55723.1 - 0.017 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Mid2 PF04478.12 EGO55723.1 - 0.044 13.6 4.0 0.43 10.4 0.1 2.9 3 0 0 3 3 3 0 Mid2 like cell wall stress sensor DUF4207 PF13904.6 EGO55723.1 - 0.08 12.6 15.4 8.2 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Podoplanin PF05808.11 EGO55723.1 - 0.13 12.4 1.8 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Podoplanin EphA2_TM PF14575.6 EGO55723.1 - 0.46 11.4 4.1 1 10.3 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 EGO55723.1 - 6.2 6.6 13.0 1.1 9.1 0.1 2.5 2 0 0 2 2 2 0 Transmembrane protein 51 EIIBC-GUT_N PF03612.14 EGO55723.1 - 7.4 6.3 7.7 0.76 9.5 0.9 2.7 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus zf-RING_2 PF13639.6 EGO55724.1 - 7.1e-08 32.7 14.8 1.1e-07 32.0 14.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGO55724.1 - 1.1e-05 25.2 9.4 1.6e-05 24.7 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO55724.1 - 1.2e-05 25.1 15.1 1.8e-05 24.4 15.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO55724.1 - 1.8e-05 24.5 10.2 2.9e-05 23.8 10.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGO55724.1 - 0.004 17.4 13.6 0.013 15.8 13.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 EGO55724.1 - 2 8.3 7.0 3.6 7.5 7.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 EGO55724.1 - 3 7.7 8.1 6.2 6.7 8.1 1.5 1 0 0 1 1 1 0 RING-like zinc finger Drc1-Sld2 PF11719.8 EGO55725.1 - 5.4e-37 128.4 10.1 6.1e-37 128.2 10.1 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein Swi5 PF07061.11 EGO55725.1 - 2.2 8.4 6.1 1.4 9.0 3.8 1.8 2 1 0 2 2 2 0 Swi5 Drc1-Sld2 PF11719.8 EGO55726.1 - 7.5e-129 431.2 48.0 1.9e-128 429.9 48.0 1.6 1 1 0 1 1 1 1 DNA replication and checkpoint protein Glyco_hydro_61 PF03443.14 EGO55727.1 - 1e-55 188.9 0.1 1.2e-55 188.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SH3_3 PF08239.11 EGO55727.1 - 0.019 15.2 0.9 0.18 12.1 0.9 2.3 1 1 0 1 1 1 0 Bacterial SH3 domain DUF2939 PF11159.8 EGO55728.1 - 0.43 11.0 2.6 4.3 7.8 0.3 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF2939) MFS_1 PF07690.16 EGO55730.1 - 1e-39 136.5 35.9 1.6e-39 135.8 35.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily CLP1_P PF16575.5 EGO55731.1 - 2.5e-29 102.4 0.0 5.8e-29 101.2 0.0 1.7 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 EGO55731.1 - 0.0061 17.0 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_16 PF13191.6 EGO55731.1 - 0.028 14.8 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Trypan_PARP PF05887.11 EGO55731.1 - 4.9 7.1 6.0 0.71 9.9 0.9 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) RNA_polI_A34 PF08208.11 EGO55732.1 - 3.1e-45 154.8 7.4 3.1e-45 154.8 7.4 5.2 2 1 2 4 4 4 1 DNA-directed RNA polymerase I subunit RPA34.5 Glyco_hydro_47 PF01532.20 EGO55734.1 - 5.4e-177 589.3 0.2 7.5e-177 588.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MRPL52 PF18699.1 EGO55734.1 - 5.1 7.3 7.6 13 6.1 2.2 2.9 3 0 0 3 3 3 0 Mitoribosomal protein mL52 Pkinase PF00069.25 EGO55735.1 - 5.5e-63 212.8 0.0 5.5e-63 212.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO55735.1 - 7.6e-49 166.3 0.0 1.5e-48 165.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO55735.1 - 1.6e-08 34.2 0.0 4.5e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like TFIIA PF03153.13 EGO55735.1 - 2e-05 24.8 44.4 6.8e-05 23.0 39.5 2.7 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Kdo PF06293.14 EGO55735.1 - 0.011 15.2 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGO55735.1 - 0.032 13.0 8.7 0.033 12.9 0.0 2.5 2 0 0 2 2 2 0 Fungal protein kinase Glyco_hydro_5_C PF18564.1 EGO55736.1 - 4.9e-22 78.3 0.1 1.2e-21 77.0 0.1 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 EGO55736.1 - 9.3e-13 48.2 4.1 1.2e-07 31.5 1.2 2.4 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 EGO55736.1 - 0.0015 18.0 0.1 1.3 8.3 0.0 2.2 2 0 0 2 2 2 2 Beta-galactosidase Drc1-Sld2 PF11719.8 EGO55736.1 - 0.1 12.1 0.1 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Tom7 PF08038.12 EGO55736.1 - 0.18 11.5 0.1 0.43 10.3 0.1 1.7 1 0 0 1 1 1 0 TOM7 family DNA_primase_S PF01896.19 EGO55737.1 - 5.8e-64 215.4 0.4 9.3e-64 214.7 0.4 1.3 1 0 0 1 1 1 1 DNA primase small subunit tRNA_m1G_MT PF01746.21 EGO55738.1 - 3.8e-25 88.7 0.0 9.5e-18 64.6 0.0 2.5 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase DUF349 PF03993.12 EGO55738.1 - 0.012 15.9 11.9 0.066 13.5 10.4 3.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Dicty_REP PF05086.12 EGO55738.1 - 1.1 7.1 12.7 1.5 6.7 12.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ndc1_Nup PF09531.10 EGO55738.1 - 1.3 7.6 15.1 1.8 7.1 15.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 EGO55738.1 - 3.2 7.7 27.5 0.68 9.9 23.4 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MutS_V PF00488.21 EGO55739.1 - 2.4e-83 278.8 0.2 3.9e-83 278.1 0.2 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGO55739.1 - 5.6e-38 131.1 2.7 6e-38 131.0 0.9 2.0 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EGO55739.1 - 2e-25 89.7 0.6 6e-25 88.1 0.1 2.2 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.20 EGO55739.1 - 2.5e-20 72.8 0.0 1.8e-19 70.0 0.0 2.4 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 EGO55739.1 - 1.8e-19 69.9 0.6 1.8e-19 69.9 0.6 2.8 4 0 0 4 4 4 1 MutS family domain IV AAA_27 PF13514.6 EGO55739.1 - 0.1 12.2 0.0 0.3 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ilm1 PF10311.9 EGO55740.1 - 1.5e-64 216.6 0.3 1.8e-64 216.4 0.3 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Prenyltrans PF00432.21 EGO55741.1 - 7e-34 115.3 8.9 2.8e-09 36.5 0.0 6.2 5 2 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Peptidase_M20 PF01546.28 EGO55742.1 - 2.3e-20 73.2 1.1 2e-18 66.8 1.1 2.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGO55742.1 - 9.3e-18 64.1 0.2 1.7e-17 63.3 0.2 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGO55742.1 - 0.043 13.5 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 IF-2B PF01008.17 EGO55743.1 - 5.1e-76 255.6 2.2 6e-76 255.3 2.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Poly_export PF02563.16 EGO55743.1 - 0.55 10.5 2.0 4 7.7 0.2 2.6 3 0 0 3 3 3 0 Polysaccharide biosynthesis/export protein TRAPPC10 PF12584.8 EGO55744.1 - 8.1e-27 93.8 0.2 1.5e-26 92.9 0.2 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Rpn3_C PF08375.11 EGO55745.1 - 5.5e-26 90.8 1.6 1.7e-25 89.2 1.6 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EGO55745.1 - 4e-21 75.5 0.5 7.9e-20 71.3 0.0 2.9 4 0 0 4 4 4 1 PCI domain TPR_2 PF07719.17 EGO55745.1 - 0.0099 15.9 0.1 0.031 14.4 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Sigma70_r1_2 PF00140.20 EGO55745.1 - 1.7 8.8 4.1 1.9 8.5 1.6 2.4 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 TFIID_20kDa PF03847.13 EGO55746.1 - 3.7e-15 56.2 0.0 5.8e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DASH_Spc34 PF08657.10 EGO55749.1 - 2e-53 181.8 0.4 1.2e-26 94.0 0.0 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 Spectrin PF00435.21 EGO55749.1 - 0.025 15.0 3.5 3.5 8.2 0.6 2.3 1 1 1 2 2 2 0 Spectrin repeat DASH_Spc19 PF08287.11 EGO55749.1 - 2.1 8.2 11.4 3.7 7.4 11.4 1.4 1 0 0 1 1 1 0 Spc19 DSBA PF01323.20 EGO55750.1 - 4.5e-42 144.0 0.0 5.1e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EGO55750.1 - 3.1e-05 24.2 0.0 0.00011 22.5 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 EGO55750.1 - 0.0077 16.3 0.1 0.092 12.8 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin domain Fig1 PF12351.8 EGO55751.1 - 2.7e-56 190.5 5.0 2.7e-56 190.5 5.0 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EGO55751.1 - 7.2e-08 32.3 9.8 1.1e-07 31.7 9.8 1.3 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 EGO55751.1 - 0.028 13.5 12.4 0.047 12.7 12.4 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF2207 PF09972.9 EGO55751.1 - 6.5 5.4 18.5 0.2 10.4 0.6 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) NatB_MDM20 PF09797.9 EGO55752.1 - 2.7e-83 280.1 0.0 8.8e-83 278.3 0.0 1.9 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit DUF3984 PF13136.6 EGO55752.1 - 0.0016 17.9 0.2 0.0027 17.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) CHCH PF06747.13 EGO55753.1 - 9.1e-05 22.5 3.3 0.00014 21.9 3.3 1.4 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 EGO55753.1 - 0.0016 18.6 4.1 0.0022 18.2 4.1 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 EGO55753.1 - 0.016 15.5 4.4 0.025 14.9 4.4 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 WBS_methylT PF12589.8 EGO55753.1 - 0.091 13.5 3.5 0.13 13.1 3.5 1.4 1 1 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome Glyco_hydro_76 PF03663.14 EGO55754.1 - 5.6e-139 463.7 3.5 8.2e-139 463.2 3.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EGO55754.1 - 0.064 12.3 3.1 0.37 9.8 0.2 2.3 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 Sugarporin_N PF11471.8 EGO55755.1 - 3.7 7.6 6.4 0.23 11.4 0.7 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Fungal_trans PF04082.18 EGO55756.1 - 4.5e-12 45.5 0.0 8.3e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO55756.1 - 1.4e-05 25.1 10.3 2.4e-05 24.4 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Roughex PF06020.11 EGO55756.1 - 0.049 12.7 5.1 0.1 11.7 5.1 1.5 1 0 0 1 1 1 0 Drosophila roughex protein SPX PF03105.19 EGO55756.1 - 1.5 8.7 18.7 0.65 9.9 2.9 2.5 2 0 0 2 2 2 0 SPX domain DUF604 PF04646.12 EGO55757.1 - 7.4e-14 51.8 0.0 2e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 EGO55757.1 - 6e-07 29.1 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Fringe-like CVNH PF08881.10 EGO55758.1 - 1.6e-11 44.8 0.1 1e-07 32.5 0.0 2.3 2 0 0 2 2 2 2 CVNH domain RabGAP-TBC PF00566.18 EGO55759.1 - 7.4e-33 114.0 0.0 1.3e-32 113.2 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 EGO55759.1 - 3.7e-06 25.5 0.5 6.5e-06 24.7 0.5 1.3 1 0 0 1 1 1 1 SBE2, cell-wall formation FA_desaturase PF00487.24 EGO55760.1 - 2.1e-22 80.2 23.6 5.6e-22 78.8 23.6 1.7 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EGO55760.1 - 1.2e-05 25.5 0.0 3.4e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) eIF2A PF08662.11 EGO55761.1 - 1.4e-37 129.5 4.2 4.2e-36 124.6 0.4 3.9 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EGO55761.1 - 0.0019 18.0 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EGO55761.1 - 0.021 15.7 0.6 6.8 7.7 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat Cpn60_TCP1 PF00118.24 EGO55762.1 - 1.5e-142 475.7 12.6 1.7e-142 475.5 12.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 EGO55762.1 - 0.043 14.0 0.2 0.12 12.6 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5442) CRM1_repeat PF18777.1 EGO55762.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat SWIB PF02201.18 EGO55764.1 - 4e-30 103.5 0.4 8.8e-30 102.4 0.4 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 EGO55764.1 - 4.6e-14 52.1 3.3 6.7e-14 51.5 2.1 1.9 2 0 0 2 2 2 1 DEK C terminal domain SRP-alpha_N PF04086.13 EGO55764.1 - 0.11 12.4 14.6 0.13 12.2 14.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal zf-C3HC4_3 PF13920.6 EGO55765.1 - 1.2e-07 31.5 9.1 1.2e-07 31.5 9.1 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO55765.1 - 0.00066 19.5 12.0 0.00066 19.5 12.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO55765.1 - 0.0037 17.6 11.8 0.0037 17.6 11.8 2.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGO55765.1 - 0.005 16.7 12.5 0.005 16.7 12.5 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 EGO55766.1 - 1.5e-45 155.6 0.0 4.9e-33 114.6 0.0 3.1 3 0 0 3 3 3 2 Protein kinase domain Ribonuc_2-5A PF06479.12 EGO55766.1 - 1.9e-43 147.7 0.0 3.3e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 EGO55766.1 - 2.1e-23 82.9 0.0 4.1e-20 72.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO55766.1 - 0.00014 20.8 0.0 0.00069 18.5 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase PQQ PF01011.21 EGO55766.1 - 0.00035 20.3 0.7 0.069 13.1 0.0 3.1 3 0 0 3 3 3 1 PQQ enzyme repeat Kdo PF06293.14 EGO55766.1 - 0.00036 19.9 0.0 0.00065 19.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO55766.1 - 0.0011 18.9 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family PQQ_2 PF13360.6 EGO55766.1 - 0.016 14.8 0.1 35 3.9 0.0 2.1 1 1 0 1 1 1 0 PQQ-like domain Cu-oxidase_2 PF07731.14 EGO55767.1 - 3.4e-43 146.7 5.2 2.8e-41 140.5 0.3 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGO55767.1 - 2e-42 143.9 0.8 6.9e-42 142.2 0.8 2.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 EGO55767.1 - 1.3e-32 113.1 0.0 4.5e-32 111.4 0.0 1.9 1 0 0 1 1 1 1 Multicopper oxidase CRAL_TRIO PF00650.20 EGO55768.1 - 2e-15 56.8 0.0 3.1e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGO55768.1 - 0.00052 20.1 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGO55768.1 - 0.096 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain MFS_MOT1 PF16983.5 EGO55770.1 - 0.37 11.2 3.1 0.52 10.7 0.8 2.1 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Asp PF00026.23 EGO55771.1 - 8e-42 143.8 0.0 1.1e-41 143.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO55771.1 - 4.2e-10 40.1 0.6 2.5e-08 34.4 0.6 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO55771.1 - 0.0085 16.7 0.1 1.6 9.4 0.0 3.3 3 0 0 3 3 3 1 Aspartyl protease DPBB_1 PF03330.18 EGO55772.1 - 1.3e-10 41.4 0.2 3.3e-10 40.1 0.2 1.6 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EGO55772.1 - 2.9e-06 27.1 0.2 3.9e-06 26.7 0.2 1.2 1 1 0 1 1 1 1 Barwin family THDPS_M PF14789.6 EGO55772.1 - 0.043 13.9 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase middle TauD PF02668.16 EGO55773.1 - 4.1e-34 118.6 0.2 6.5e-34 117.9 0.2 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EGO55773.1 - 0.15 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 CsiD AA_permease_2 PF13520.6 EGO55774.1 - 2.1e-73 247.6 36.0 2.6e-73 247.3 36.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO55774.1 - 4.4e-16 58.5 30.4 5.8e-16 58.1 30.4 1.1 1 0 0 1 1 1 1 Amino acid permease NACHT PF05729.12 EGO55775.1 - 5.2e-11 42.7 0.1 1.3e-10 41.4 0.1 1.7 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 EGO55775.1 - 1.3e-09 37.7 0.0 6.7e-09 35.4 0.0 2.2 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 EGO55775.1 - 2.2e-06 28.0 0.1 9e-06 26.0 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGO55775.1 - 0.00027 21.4 0.0 0.001 19.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EGO55775.1 - 0.012 14.8 0.0 0.05 12.8 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 EGO55775.1 - 0.045 13.0 0.4 0.085 12.1 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EGO55775.1 - 0.048 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGO55775.1 - 0.057 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 EGO55775.1 - 0.065 13.1 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA PF00004.29 EGO55775.1 - 0.082 13.3 0.1 0.32 11.4 0.0 2.1 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EGO55775.1 - 0.12 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.11 EGO55775.1 - 0.13 12.4 0.1 0.51 10.5 0.0 2.0 2 0 0 2 2 2 0 Torsin ResIII PF04851.15 EGO55775.1 - 0.15 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TPP_enzyme_N PF02776.18 EGO55776.1 - 2.1e-35 121.9 0.1 1.1e-33 116.3 0.1 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGO55776.1 - 9.5e-25 86.9 0.0 1.9e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EGO55776.1 - 1.8e-23 83.0 0.2 3.5e-22 78.8 0.0 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fringe PF02434.16 EGO55779.1 - 3.6e-05 23.3 1.5 0.00037 20.0 1.5 2.2 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 EGO55779.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Galactosyltransferase Oxysterol_BP PF01237.18 EGO55780.1 - 2.8e-56 191.0 0.0 4.6e-48 163.9 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Sugar_tr PF00083.24 EGO55782.1 - 2.6e-99 333.2 29.0 3.3e-99 332.8 29.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO55782.1 - 9.1e-23 80.7 37.3 1.9e-21 76.4 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SAD_SRA PF02182.17 EGO55783.1 - 4.2e-31 107.8 0.0 6.5e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain Herpes_U47 PF05467.11 EGO55783.1 - 0.2 9.7 2.4 0.27 9.3 2.4 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 FAD_binding_2 PF00890.24 EGO55784.1 - 5.2e-91 305.8 0.0 5.9e-91 305.6 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGO55784.1 - 4.6e-07 30.0 0.1 1.9e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGO55784.1 - 0.0039 16.5 0.0 0.0094 15.2 0.0 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EGO55784.1 - 0.0071 15.1 2.2 0.15 10.7 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 EGO55784.1 - 0.01 15.4 0.0 0.032 13.8 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 EGO55784.1 - 0.014 14.5 0.0 0.029 13.5 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EGO55784.1 - 0.017 15.1 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EGO55784.1 - 0.03 13.6 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 EGO55784.1 - 0.031 13.5 0.4 0.36 10.0 0.0 2.7 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO55784.1 - 0.048 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD-oxidase_C PF02913.19 EGO55786.1 - 3.7e-61 206.9 0.2 7.2e-61 206.0 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGO55786.1 - 1.5e-39 134.9 0.0 2.5e-39 134.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 EGO55786.1 - 0.054 12.2 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS ANF_receptor PF01094.28 EGO55786.1 - 0.076 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Receptor family ligand binding region Glyco_hydro_76 PF03663.14 EGO55787.1 - 1.1e-147 492.4 6.8 1.3e-147 492.2 6.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 p450 PF00067.22 EGO55788.1 - 3e-66 224.1 0.0 3.9e-64 217.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 CBM_19 PF03427.13 EGO55789.1 - 0.041 13.9 7.1 0.047 13.7 7.1 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) zf-ANAPC11 PF12861.7 EGO55790.1 - 2.9 8.0 5.1 3.6 7.7 1.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Alpha-amylase PF00128.24 EGO55791.1 - 6.4e-62 210.1 0.6 8.9e-62 209.6 0.6 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EGO55791.1 - 1.4e-26 92.6 0.8 4.3e-26 91.0 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) GHL10 PF02638.15 EGO55791.1 - 0.0024 17.0 2.6 0.023 13.8 0.8 2.7 2 1 0 2 2 2 1 Glycosyl hydrolase-like 10 hDGE_amylase PF14701.6 EGO55791.1 - 0.0068 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Aminotran_5 PF00266.19 EGO55791.1 - 0.12 11.2 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Alpha-amylase PF00128.24 EGO55792.1 - 1.1e-21 77.8 2.5 5.5e-19 68.9 1.4 2.6 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 EGO55792.1 - 5e-18 65.7 0.4 9.2e-18 64.8 0.4 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EGO55792.1 - 2.2e-07 30.6 0.0 4.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGO55792.1 - 0.0019 18.2 0.5 0.057 13.4 0.0 2.9 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Pro_CA PF00484.19 EGO55793.1 - 1.7e-51 174.6 0.0 2.5e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase zf-C2H2_4 PF13894.6 EGO55794.1 - 1.2e-19 69.3 20.5 0.0012 19.5 0.3 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO55794.1 - 3.2e-19 68.2 19.6 0.025 15.0 0.4 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EGO55794.1 - 4.1e-13 49.2 19.4 0.0035 17.6 0.3 6.0 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EGO55794.1 - 1.3e-08 34.9 18.2 0.0059 17.0 0.5 5.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 EGO55794.1 - 1.4e-08 34.5 14.9 0.024 14.7 0.5 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EGO55794.1 - 1.4e-07 31.7 22.3 0.069 13.5 9.2 5.9 2 2 2 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EGO55794.1 - 1.7e-07 31.4 16.8 0.72 10.3 0.2 6.0 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EGO55794.1 - 9.6e-05 22.1 1.8 2.6 7.9 0.0 4.2 5 0 0 5 5 5 1 zinc-finger C2H2-type zf_UBZ PF18439.1 EGO55794.1 - 0.0001 21.8 25.0 0.22 11.2 1.9 5.9 6 0 0 6 6 6 3 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 EGO55794.1 - 0.00065 19.5 14.9 2.2 8.3 0.5 5.3 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf_C2H2_10 PF18414.1 EGO55794.1 - 0.00082 18.9 9.5 0.31 10.6 0.0 4.4 5 0 0 5 5 5 2 C2H2 type zinc-finger zf-C2HE PF16278.5 EGO55794.1 - 0.0014 19.0 20.8 0.12 12.8 0.7 4.3 2 2 2 4 4 4 3 C2HE / C2H2 / C2HC zinc-binding finger zf-DNL PF05180.12 EGO55794.1 - 0.0032 17.4 1.4 0.0032 17.4 1.4 3.2 3 1 1 4 4 3 1 DNL zinc finger zf-C2H2_9 PF16293.5 EGO55794.1 - 0.0041 16.9 10.6 4.4 7.2 0.1 5.1 4 2 1 5 5 5 1 C2H2 type zinc-finger (1 copy) Vps36-NZF-N PF16988.5 EGO55794.1 - 0.0071 15.7 5.2 4.7 6.7 0.6 3.9 3 1 1 4 4 4 2 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_8 PF15909.5 EGO55794.1 - 0.02 15.2 7.9 0.21 11.9 0.2 3.2 1 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 EGO55794.1 - 0.031 15.0 10.8 1.8 9.3 0.3 4.1 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 EGO55794.1 - 0.033 14.5 18.2 0.46 10.8 3.6 4.2 3 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_15 PF17032.5 EGO55794.1 - 0.057 14.2 16.6 0.45 11.3 1.8 3.5 2 2 0 2 2 2 0 zinc-ribbon family zf_C2H2_ZHX PF18387.1 EGO55794.1 - 0.068 12.8 18.2 1.1 9.0 0.0 5.1 3 2 2 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain HypA PF01155.19 EGO55794.1 - 0.1 12.6 15.2 59 3.7 12.4 2.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-C2H2_12 PF18112.1 EGO55794.1 - 0.12 12.8 0.3 0.12 12.8 0.3 6.3 6 0 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain Actin_micro PF17003.5 EGO55794.1 - 2.6 7.2 17.7 0.57 9.3 1.6 3.3 1 1 2 3 3 3 0 Putative actin-like family DUF629 PF04780.12 EGO55794.1 - 5.2 5.5 21.3 2.6 6.5 1.5 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF629) DUF3176 PF11374.8 EGO55795.1 - 7.4e-22 77.6 0.0 1.8e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) MutS_V PF00488.21 EGO55796.1 - 6e-68 228.6 0.2 1.2e-67 227.6 0.2 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGO55796.1 - 4e-42 144.6 0.1 9.2e-42 143.4 0.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EGO55796.1 - 5.3e-33 113.6 0.1 1.3e-32 112.4 0.0 1.7 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 EGO55796.1 - 6.2e-15 55.7 0.3 3.3e-14 53.3 0.0 2.3 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EGO55796.1 - 3.2e-13 49.8 0.4 6.1e-13 48.9 0.4 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 EGO55796.1 - 0.02 15.4 1.5 0.055 14.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGO55796.1 - 0.03 14.1 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 EGO55796.1 - 0.038 13.6 0.1 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EGO55796.1 - 0.95 9.2 4.6 0.6 9.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system CDC45 PF02724.14 EGO55796.1 - 2 6.6 5.2 3.6 5.8 5.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Corona_nucleoca PF00937.18 EGO55797.1 - 0.03 13.4 0.2 0.03 13.4 0.2 2.0 3 0 0 3 3 3 0 Coronavirus nucleocapsid protein S36_mt PF10937.8 EGO55798.1 - 1.3e-41 142.8 0.4 1.6e-41 142.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Cyto_heme_lyase PF01265.17 EGO55799.1 - 1.9e-45 155.7 11.4 2.5e-43 148.7 11.4 3.1 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Pex14_N PF04695.13 EGO55799.1 - 1.7 9.3 11.8 3 8.5 11.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 EGO55799.1 - 2.6 8.0 8.0 3.1 7.7 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF647 PF04884.14 EGO55800.1 - 1e-89 300.4 0.7 1.2e-89 300.1 0.7 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis MDD_C PF18376.1 EGO55801.1 - 1.7e-64 217.0 0.3 2.2e-64 216.7 0.3 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EGO55801.1 - 2.7e-08 33.9 3.6 3.2e-08 33.7 1.5 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain MFS_1 PF07690.16 EGO55804.1 - 1.5e-16 60.3 14.2 1.5e-16 60.3 14.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily RACo_linker PF17650.1 EGO55804.1 - 0.082 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 RACo linker region DUF2383 PF09537.10 EGO55804.1 - 0.1 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) CoA_trans PF01144.23 EGO55805.1 - 4e-75 251.9 0.4 1.5e-38 132.4 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EGO55805.1 - 0.00021 21.3 0.2 0.00042 20.3 0.2 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 EGO55805.1 - 0.0091 14.4 0.6 0.017 13.5 0.1 1.6 2 0 0 2 2 2 1 Malonate decarboxylase, alpha subunit, transporter CBP PF12192.8 EGO55806.1 - 0.038 14.2 1.0 0.13 12.5 1.0 1.8 1 0 0 1 1 1 0 Fungal calcium binding protein E1-E2_ATPase PF00122.20 EGO55807.1 - 1.3e-35 122.5 11.0 3.4e-30 104.9 0.1 3.6 3 1 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGO55807.1 - 5.4e-29 101.2 0.9 5.4e-29 101.2 0.9 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGO55807.1 - 8.2e-18 65.5 1.5 8.2e-17 62.2 1.5 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGO55807.1 - 7.8e-17 60.7 0.0 2.1e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGO55807.1 - 4.1e-14 52.4 0.0 8.2e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGO55807.1 - 3.7e-06 26.9 1.9 0.00017 21.4 0.7 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IncE PF17627.2 EGO55807.1 - 0.0076 16.3 1.2 0.031 14.3 1.2 2.1 1 0 0 1 1 1 1 Inclusion membrane protein E Nucleos_tra2_C PF07662.13 EGO55808.1 - 1.1e-73 247.5 2.0 1.1e-73 247.5 2.0 2.4 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EGO55808.1 - 5.8e-22 78.1 1.2 5.8e-22 78.1 1.2 2.8 3 1 1 4 4 4 1 Na+ dependent nucleoside transporter N-terminus ATP1G1_PLM_MAT8 PF02038.16 EGO55808.1 - 0.17 11.4 2.9 0.52 9.8 2.9 1.8 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Gate PF07670.14 EGO55808.1 - 4.8 7.5 17.5 2.3 8.5 9.1 3.9 2 1 1 3 3 3 0 Nucleoside recognition Epiglycanin_C PF14654.6 EGO55810.1 - 2.1 8.5 6.4 3.5 7.7 2.2 2.6 2 1 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region PNK3P PF08645.11 EGO55811.1 - 8.7e-58 194.6 0.0 1.3e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EGO55811.1 - 2e-27 96.1 0.0 2.7e-14 53.5 0.0 2.4 1 1 1 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EGO55811.1 - 0.018 14.3 0.0 6 6.1 0.0 2.3 1 1 1 2 2 2 0 Zeta toxin KTI12 PF08433.10 EGO55811.1 - 0.042 13.3 0.1 2.4 7.5 0.0 2.3 1 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_29 PF13555.6 EGO55811.1 - 0.062 13.0 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EGO55811.1 - 0.063 13.8 0.1 5.7 7.5 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 EGO55811.1 - 0.19 12.1 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Sugar_tr PF00083.24 EGO55812.1 - 1.6e-109 366.8 20.7 1.9e-109 366.6 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO55812.1 - 5.3e-26 91.4 47.7 1.4e-22 80.2 20.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 EGO55812.1 - 0.005 15.8 0.5 0.011 14.7 0.5 1.5 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM DUF3487 PF11990.8 EGO55812.1 - 7.2 6.5 7.8 29 4.6 0.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) PhoD PF09423.10 EGO55813.1 - 2e-111 372.4 0.2 2.5e-111 372.1 0.2 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EGO55813.1 - 4.9e-35 120.0 0.2 1.1e-34 118.8 0.2 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EGO55813.1 - 0.0004 20.9 0.7 0.0013 19.2 0.7 1.9 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Pep1_7 PF17232.2 EGO55814.1 - 0.011 16.2 1.6 1.4 9.4 0.2 2.6 2 0 0 2 2 2 0 Elicitor peptide 1-7 Abhydrolase_6 PF12697.7 EGO55816.1 - 5e-10 40.4 0.7 6.8e-10 39.9 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO55816.1 - 0.00054 19.7 0.1 0.0066 16.1 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF5010_C PF18099.1 EGO55816.1 - 0.081 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 DUF5010 C-terminal domain SR-25 PF10500.9 EGO55816.1 - 0.19 11.3 7.7 0.35 10.4 7.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 EGO55816.1 - 3.7 5.9 8.5 5.2 5.4 8.5 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) CBM_48 PF02922.18 EGO55817.1 - 0.3 11.4 1.3 21 5.5 0.0 3.9 4 1 0 4 4 4 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Ycf1 PF05758.12 EGO55817.1 - 1.6 6.5 6.7 2.6 5.8 6.7 1.4 1 0 0 1 1 1 0 Ycf1 DSPc PF00782.20 EGO55818.1 - 1.6e-15 57.1 0.1 1.3e-09 38.0 0.0 3.1 1 1 1 2 2 2 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EGO55818.1 - 0.045 14.1 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EGO55818.1 - 0.055 13.0 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-C2H2 PF00096.26 EGO55819.1 - 0.21 12.1 21.8 0.48 11.0 0.7 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-CHCC PF10276.9 EGO55819.1 - 0.54 10.4 3.7 5.2 7.2 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger domain Zn_ribbon_recom PF13408.6 EGO55819.1 - 4.8 7.8 6.9 10 6.7 0.6 2.8 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain zf-C2H2_4 PF13894.6 EGO55819.1 - 7.7 7.7 22.7 0.82 10.7 1.2 5.0 4 0 0 4 4 4 0 C2H2-type zinc finger Rtt106 PF08512.12 EGO55821.1 - 1.4e-30 105.5 0.0 3.9e-30 104.1 0.0 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 EGO55821.1 - 0.0077 16.2 0.0 0.073 13.0 0.0 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain Cwf_Cwc_15 PF04889.12 EGO55821.1 - 6.5 6.4 20.7 12 5.6 20.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Lyase_1 PF00206.20 EGO55822.1 - 7.8e-92 308.0 0.0 1.1e-91 307.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EGO55822.1 - 5.1e-26 91.2 0.0 1.3e-25 89.9 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Vfa1 PF08432.10 EGO55823.1 - 4.3e-57 193.4 25.0 4.8e-57 193.2 25.0 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF908 PF06012.12 EGO55823.1 - 0.027 13.9 5.8 0.027 13.9 5.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) RR_TM4-6 PF06459.12 EGO55823.1 - 0.068 13.0 16.7 0.082 12.7 16.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF262 PF03235.14 EGO55823.1 - 0.072 13.3 7.6 0.11 12.7 7.6 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF262 Pox_Ag35 PF03286.14 EGO55823.1 - 0.098 12.4 19.1 0.15 11.8 19.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SAPS PF04499.15 EGO55823.1 - 0.1 11.3 8.9 0.11 11.3 8.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDHD PF02862.17 EGO55823.1 - 0.18 12.0 5.5 0.2 11.8 5.5 1.2 1 0 0 1 1 1 0 DDHD domain TraH_2 PF06871.11 EGO55823.1 - 0.21 11.2 1.5 0.24 11.0 1.5 1.1 1 0 0 1 1 1 0 TraH_2 DUF2052 PF09747.9 EGO55823.1 - 0.36 10.9 21.0 0.48 10.5 21.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) AAA_11 PF13086.6 EGO55823.1 - 0.37 10.6 9.3 0.45 10.3 9.3 1.2 1 0 0 1 1 1 0 AAA domain SLC12 PF03522.15 EGO55823.1 - 0.42 9.6 10.7 0.45 9.5 10.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF913 PF06025.12 EGO55823.1 - 0.7 8.8 7.1 0.74 8.7 7.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 EGO55823.1 - 1.2 7.3 24.1 1.5 7.1 24.1 1.0 1 0 0 1 1 1 0 CDC45-like protein SpoIIP PF07454.11 EGO55823.1 - 1.4 8.3 14.3 1.7 8.0 14.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Slu7 PF11708.8 EGO55823.1 - 1.6 8.4 24.1 2.4 7.8 24.1 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor U79_P34 PF03064.16 EGO55823.1 - 1.8 7.8 23.8 3.1 7.1 23.8 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1682 PF07946.14 EGO55823.1 - 1.9 7.6 19.1 2.8 7.1 19.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF2457 PF10446.9 EGO55823.1 - 2.2 7.3 26.4 3.4 6.7 26.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Paramyxo_ncap PF00973.19 EGO55823.1 - 2.3 7.0 7.0 2.6 6.9 7.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CLN3 PF02487.17 EGO55823.1 - 2.4 7.1 4.0 2.7 6.9 4.0 1.2 1 0 0 1 1 1 0 CLN3 protein TP53IP5 PF15331.6 EGO55823.1 - 3.5 7.7 17.9 4.8 7.3 17.9 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Presenilin PF01080.17 EGO55823.1 - 3.6 6.3 14.5 4.3 6.0 14.5 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 EGO55823.1 - 3.8 7.5 6.7 4 7.4 6.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 EGO55823.1 - 3.8 6.6 9.0 4.4 6.4 9.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Selenoprotein_S PF06936.11 EGO55823.1 - 4.9 6.9 19.0 8.2 6.2 19.0 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) MMU163 PF17119.5 EGO55823.1 - 5.6 6.0 9.4 7.6 5.6 9.4 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Afi1 PF07792.12 EGO55823.1 - 5.7 7.4 16.3 10 6.6 16.3 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4407 PF14362.6 EGO55823.1 - 6.5 6.0 10.2 8.4 5.7 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FancD2 PF14631.6 EGO55823.1 - 6.9 3.9 15.9 8.5 3.6 15.9 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Serinc PF03348.15 EGO55823.1 - 7.2 5.4 5.1 8.2 5.2 5.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) NPR3 PF03666.13 EGO55823.1 - 7.6 5.2 17.9 9 5.0 17.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AAA_13 PF13166.6 EGO55823.1 - 7.7 5.0 20.8 9.7 4.7 20.8 1.1 1 0 0 1 1 1 0 AAA domain GCD14 PF08704.10 EGO55823.1 - 8.1 6.0 8.1 11 5.6 8.1 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PPL5 PF18168.1 EGO55823.1 - 9.2 5.5 13.9 13 5.0 13.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 adh_short PF00106.25 EGO55825.1 - 2.2e-24 86.0 0.0 1.1e-17 64.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO55825.1 - 4.7e-16 59.0 0.0 1.1e-10 41.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO55825.1 - 1.3e-05 25.2 0.1 2e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF3169 PF11368.8 EGO55826.1 - 0.00038 20.1 0.7 0.00061 19.4 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3169) BCCT PF02028.17 EGO55826.1 - 0.00043 18.9 0.1 0.00068 18.2 0.1 1.3 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter DUF3720 PF12517.8 EGO55826.1 - 0.008 17.1 1.0 0.008 17.1 1.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3720) MCU PF04678.13 EGO55827.1 - 4e-26 92.2 0.1 4e-26 92.2 0.1 2.4 3 0 0 3 3 3 1 Mitochondrial calcium uniporter Ribosomal_S15 PF00312.22 EGO55827.1 - 0.032 14.4 0.1 0.077 13.2 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S15 Acetyltransf_8 PF13523.6 EGO55828.1 - 3.1e-43 146.9 0.4 4.5e-43 146.4 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CVNH PF08881.10 EGO55829.1 - 2.3e-15 57.1 3.0 3.7e-11 43.6 1.3 1.8 1 1 1 2 2 2 2 CVNH domain ASD2 PF08687.11 EGO55830.1 - 0.043 13.4 14.2 0.061 12.9 14.2 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Tim54 PF11711.8 EGO55830.1 - 0.36 9.6 9.8 0.48 9.1 9.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 eIF-3_zeta PF05091.12 EGO55830.1 - 0.42 9.5 19.2 0.69 8.8 19.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF908 PF06012.12 EGO55830.1 - 1.2 8.5 14.5 1.9 7.8 14.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SOG2 PF10428.9 EGO55830.1 - 2.3 7.3 16.2 3.3 6.8 16.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein FAM60A PF15396.6 EGO55830.1 - 3.7 7.5 10.6 6.5 6.7 10.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.9 EGO55830.1 - 3.7 5.7 33.6 4.9 5.3 33.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.7 EGO55830.1 - 7.6 6.2 16.0 13 5.4 16.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit RR_TM4-6 PF06459.12 EGO55830.1 - 9.8 5.9 18.9 12 5.6 17.5 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 ABM PF03992.16 EGO55831.1 - 8e-06 25.9 0.0 0.047 13.8 0.0 2.1 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase OPT PF03169.15 EGO55832.1 - 5.1e-139 464.7 50.8 5.8e-139 464.5 50.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MARVEL PF01284.23 EGO55834.1 - 0.0025 17.9 19.1 0.0039 17.2 19.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.11 EGO55834.1 - 0.018 15.0 16.4 0.17 11.8 11.7 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF4293 PF14126.6 EGO55834.1 - 0.43 10.8 6.6 0.12 12.7 3.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF3176 PF11374.8 EGO55836.1 - 8.3e-21 74.2 0.0 3.4e-20 72.2 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3176) FAD_binding_3 PF01494.19 EGO55837.1 - 1.8e-19 70.2 3.2 9.8e-12 44.8 0.3 2.7 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EGO55837.1 - 9.2e-06 25.8 0.1 2.5e-05 24.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO55837.1 - 0.0015 17.8 0.4 0.012 14.9 0.4 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGO55837.1 - 0.0021 17.2 0.1 0.0027 16.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EGO55837.1 - 0.013 16.0 0.1 0.17 12.4 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGO55837.1 - 0.037 13.3 0.0 0.4 9.9 0.0 2.3 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EGO55837.1 - 0.042 13.1 0.1 0.37 10.0 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EGO55837.1 - 0.05 12.6 0.0 0.99 8.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Lycopene_cycl PF05834.12 EGO55837.1 - 0.08 12.0 0.1 0.44 9.5 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 EGO55837.1 - 0.1 12.7 0.4 8.9 6.4 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 EGO55837.1 - 0.14 11.4 0.1 0.26 10.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 EGO55837.1 - 0.2 11.2 0.7 0.31 10.6 0.1 1.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase Zn_clus PF00172.18 EGO55838.1 - 1.7e-08 34.4 10.6 2.6e-08 33.8 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGO55838.1 - 0.011 14.8 0.3 0.037 13.0 0.1 1.9 1 1 1 2 2 2 0 Fungal specific transcription factor domain FliG_C PF01706.16 EGO55838.1 - 0.12 12.6 0.2 0.26 11.5 0.2 1.5 1 0 0 1 1 1 0 FliG C-terminal domain Clr5 PF14420.6 EGO55839.1 - 7.5e-20 70.9 7.2 8.2e-18 64.4 5.5 2.5 2 0 0 2 2 2 2 Clr5 domain TPR_12 PF13424.6 EGO55839.1 - 0.011 16.0 0.9 1.5 9.2 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_79C PF16862.5 EGO55842.1 - 1.5e-20 74.0 0.8 3.5e-20 72.8 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain NUP PF06516.11 EGO55843.1 - 1.1e-133 445.4 0.1 1.3e-133 445.1 0.1 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Pkinase PF00069.25 EGO55844.1 - 3.7e-41 141.2 0.0 1.1e-40 139.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO55844.1 - 2.2e-29 102.6 0.0 3.1e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO55844.1 - 0.0098 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGO55844.1 - 0.044 13.1 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pectate_lyase PF03211.13 EGO55845.1 - 5.6e-86 287.3 6.2 6.6e-86 287.0 6.2 1.0 1 0 0 1 1 1 1 Pectate lyase Pkinase PF00069.25 EGO55846.1 - 2e-07 30.7 0.0 0.12 11.8 0.0 3.6 3 1 0 3 3 3 3 Protein kinase domain Sugar_tr PF00083.24 EGO55847.1 - 2.8e-114 382.5 27.9 1.1e-107 360.7 20.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGO55847.1 - 2.7e-18 66.0 36.3 2.7e-18 66.0 36.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily GH114_assoc PF14741.6 EGO55848.1 - 0.097 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain Tyrosinase PF00264.20 EGO55849.1 - 2.6e-52 178.3 0.0 3.3e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase STE2 PF02116.15 EGO55851.1 - 2.1e-81 273.3 24.0 3e-81 272.8 24.0 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR CN_hydrolase PF00795.22 EGO55852.1 - 2.8e-56 190.8 0.1 3.2e-56 190.6 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_M4_C PF02868.15 EGO55853.1 - 5.9e-33 114.1 0.2 1e-32 113.3 0.2 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 EGO55853.1 - 7.4e-10 39.5 0.5 1.3e-08 35.5 0.5 2.7 1 1 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M13 PF01431.21 EGO55853.1 - 0.096 12.3 0.7 0.47 10.0 0.2 2.2 2 0 0 2 2 2 0 Peptidase family M13 Peptidase_C97 PF05903.14 EGO55854.1 - 0.00021 21.1 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain UEV PF05743.13 EGO55856.1 - 5.7e-36 123.0 0.1 9.2e-36 122.4 0.1 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EGO55856.1 - 2.4e-20 72.2 0.0 4.3e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Vps23 core domain ThiD2 PF17792.1 EGO55856.1 - 0.27 11.7 1.4 0.44 11.0 1.4 1.2 1 0 0 1 1 1 0 ThiD2 family TetR_C_11 PF16859.5 EGO55856.1 - 6.1 7.2 6.6 1.2 9.4 0.4 2.4 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain IDO PF01231.18 EGO55857.1 - 3.3e-170 566.6 0.0 3.8e-170 566.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Phage_antitermQ PF06530.12 EGO55857.1 - 0.22 11.4 0.2 0.53 10.2 0.1 1.6 2 0 0 2 2 2 0 Phage antitermination protein Q Lipase_GDSL_2 PF13472.6 EGO55858.1 - 6.1e-16 59.3 0.1 8.9e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGO55858.1 - 4.8e-08 33.2 0.0 9.9e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EGO55858.1 - 0.00026 21.2 0.0 0.00037 20.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DctM PF06808.12 EGO55858.1 - 0.18 10.6 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component Cauli_VI PF01693.16 EGO55859.1 - 2.2e-36 123.9 14.7 8.6e-19 67.6 4.1 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 EGO55859.1 - 3.5e-34 118.1 0.1 6.9e-34 117.1 0.1 1.5 1 0 0 1 1 1 1 RNase H COX6B PF02297.17 EGO55859.1 - 0.018 15.3 0.4 0.037 14.3 0.4 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb TIR_2 PF13676.6 EGO55859.1 - 0.025 15.2 0.0 0.082 13.5 0.0 1.8 2 0 0 2 2 2 0 TIR domain FoP_duplication PF13865.6 EGO55860.1 - 0.003 18.1 1.8 0.0065 17.0 0.1 2.1 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Rhomboid PF01694.22 EGO55860.1 - 0.072 13.1 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Rhomboid family ATP19 PF11022.8 EGO55860.1 - 0.13 12.6 1.2 0.57 10.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase subunit K ThrE PF06738.12 EGO55861.1 - 0.85 8.9 4.5 1.3 8.4 4.5 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter SirB PF04247.12 EGO55861.1 - 0.97 9.5 5.0 1.9 8.6 5.0 1.4 1 0 0 1 1 1 0 Invasion gene expression up-regulator, SirB HLH PF00010.26 EGO55865.1 - 1.1e-06 28.4 1.7 2.5e-06 27.4 1.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DASH_Spc19 PF08287.11 EGO55865.1 - 0.31 10.9 9.8 0.23 11.3 8.0 1.7 1 1 0 1 1 1 0 Spc19 DUF5595 PF18077.1 EGO55865.1 - 2.6 8.2 6.4 0.77 9.9 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Methyltransf_11 PF08241.12 EGO55866.1 - 1.1e-13 51.6 0.0 2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO55866.1 - 1.6e-12 48.0 0.0 2.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO55866.1 - 6.5e-11 42.3 0.0 9e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO55866.1 - 7.8e-11 42.0 0.0 1.1e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO55866.1 - 1.1e-10 42.1 0.0 1.6e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGO55866.1 - 5.8e-07 29.4 0.0 7.8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EGO55866.1 - 5.8e-05 22.7 0.1 0.00012 21.7 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase small domain adh_short_C2 PF13561.6 EGO55866.1 - 0.00019 21.1 0.0 0.00027 20.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF938 PF06080.12 EGO55866.1 - 0.0005 19.9 0.0 0.00079 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) adh_short PF00106.25 EGO55866.1 - 0.0011 18.4 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase TehB PF03848.14 EGO55866.1 - 0.0013 18.2 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.13 EGO55866.1 - 0.0022 17.5 0.0 0.0031 16.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EGO55866.1 - 0.0072 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EGO55866.1 - 0.033 14.3 0.3 0.096 12.8 0.3 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase TPMT PF05724.11 EGO55866.1 - 0.037 13.7 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) ADH_zinc_N PF00107.26 EGO55866.1 - 0.05 13.6 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DREV PF05219.12 EGO55866.1 - 0.16 11.0 0.1 0.48 9.5 0.0 1.9 1 1 1 2 2 2 0 DREV methyltransferase Hce2 PF14856.6 EGO55867.1 - 5.2e-10 39.5 0.0 3e-09 37.1 0.0 2.2 1 1 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Abhydrolase_2 PF02230.16 EGO55868.1 - 0.0073 16.1 0.1 0.016 15.0 0.1 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase GRP PF07172.11 EGO55869.1 - 0.0022 18.6 10.5 0.0022 18.6 10.5 4.6 2 1 0 2 2 2 1 Glycine rich protein family DUF3328 PF11807.8 EGO55870.1 - 2.6e-37 128.7 2.0 3.1e-37 128.5 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Tyrosinase PF00264.20 EGO55871.1 - 1.1e-41 143.6 0.9 1.1e-41 143.6 0.9 2.0 1 1 1 2 2 2 1 Common central domain of tyrosinase SR-25 PF10500.9 EGO55871.1 - 0.016 14.8 5.2 0.016 14.8 5.2 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3328 PF11807.8 EGO55873.1 - 5.3e-25 88.5 0.4 9.9e-25 87.6 0.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) CBM46 PF18448.1 EGO55873.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain Methyltransf_31 PF13847.6 EGO55874.1 - 8e-08 32.2 0.3 1.6e-07 31.3 0.3 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO55874.1 - 1.9e-07 31.1 0.1 5.1e-07 29.7 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO55874.1 - 1.6e-06 28.8 0.2 6.3e-06 26.8 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO55874.1 - 0.00018 22.1 0.2 0.0013 19.3 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGO55874.1 - 0.00034 20.4 0.0 0.00071 19.4 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EGO55874.1 - 0.00037 21.2 1.8 0.0012 19.6 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 EGO55874.1 - 0.0034 17.0 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 EGO55874.1 - 0.0035 17.3 0.6 0.016 15.2 0.6 2.0 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGO55874.1 - 0.014 14.7 0.0 0.092 12.0 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 EGO55874.1 - 0.024 14.7 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EGO55874.1 - 0.036 13.4 0.0 0.31 10.3 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DUF1840 PF08895.11 EGO55874.1 - 0.044 14.1 0.3 0.071 13.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) TehB PF03848.14 EGO55874.1 - 0.095 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB OmpH PF03938.14 EGO55874.1 - 3.1 8.1 9.3 2.1 8.7 6.3 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3328 PF11807.8 EGO55875.1 - 0.017 14.9 9.7 0.21 11.3 9.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) OPT PF03169.15 EGO55876.1 - 4.6e-129 431.8 43.0 5.7e-129 431.5 43.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_S41 PF03572.18 EGO55876.1 - 9.4e-09 35.0 0.0 2.3e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 Bromodomain PF00439.25 EGO55876.1 - 0.17 12.0 0.1 0.35 11.0 0.1 1.4 1 0 0 1 1 1 0 Bromodomain TFIIE-A_C PF11521.8 EGO55876.1 - 9.3 6.6 7.0 32 4.9 0.8 3.3 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha DUF3328 PF11807.8 EGO55877.1 - 7e-25 88.1 0.3 8.3e-25 87.9 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans_2 PF11951.8 EGO55878.1 - 5.9e-42 143.8 5.3 8.2e-42 143.4 5.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO55878.1 - 4.8e-07 29.8 6.1 9.5e-07 28.8 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VIT PF08487.10 EGO55879.1 - 8.1e-08 32.5 0.2 14 5.9 0.0 5.1 5 0 0 5 5 5 3 Vault protein inter-alpha-trypsin domain Herpes_IE1 PF07340.11 EGO55879.1 - 3.1e-05 23.1 2.1 4.4 6.1 0.0 4.5 1 1 4 5 5 5 3 Cytomegalovirus IE1 protein CDH PF02611.15 EGO55879.1 - 0.00025 20.7 0.1 7.5 6.1 0.0 4.1 1 1 4 5 5 5 2 CDP-diacylglycerol pyrophosphatase Sorb PF02208.16 EGO55879.1 - 0.0014 18.4 0.9 1.1e+02 2.8 0.0 5.4 6 0 0 6 6 6 0 Sorbin homologous domain HdeA PF06411.11 EGO55879.1 - 0.0029 17.8 4.8 39 4.5 0.0 4.8 1 1 3 4 4 4 0 HdeA/HdeB family DapH_N PF08503.10 EGO55879.1 - 0.0067 16.6 17.6 15 5.9 0.1 6.7 1 1 1 6 6 6 1 Tetrahydrodipicolinate succinyltransferase N-terminal VirB8 PF04335.13 EGO55879.1 - 0.065 13.1 7.2 0.73 9.6 0.1 4.9 1 1 3 6 6 6 0 VirB8 protein Endonuc-FokI_C PF09254.11 EGO55879.1 - 1.6 7.9 13.6 14 4.9 0.2 4.4 1 1 4 5 5 5 0 Restriction endonuclease FokI, C terminal Repressor_Mnt PF11423.8 EGO55881.1 - 0.067 13.0 2.2 0.15 11.8 2.2 1.6 1 0 0 1 1 1 0 Regulatory protein Mnt peroxidase PF00141.23 EGO55882.1 - 5.3e-82 274.9 0.0 5.2e-42 144.1 0.0 2.2 2 0 0 2 2 2 2 Peroxidase TFB6 PF17110.5 EGO55883.1 - 5.8e-69 231.2 0.0 7e-69 230.9 0.0 1.1 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Tom6 PF17112.5 EGO55884.1 - 0.0023 17.4 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal DUF1996 PF09362.10 EGO55885.1 - 7.3e-81 271.6 0.4 9.3e-81 271.3 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Hydrolase_4 PF12146.8 EGO55886.1 - 0.00015 21.1 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO55886.1 - 0.0003 20.5 0.0 0.00054 19.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO55886.1 - 0.00077 20.1 0.0 0.0048 17.5 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Aa_trans PF01490.18 EGO55888.1 - 1.4e-77 261.1 27.2 1.8e-77 260.8 27.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4746 PF15928.5 EGO55888.1 - 0.086 12.3 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) OST3_OST6 PF04756.13 EGO55888.1 - 0.12 11.7 3.9 0.67 9.3 0.4 2.4 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family FA_desaturase PF00487.24 EGO55888.1 - 2.7 7.7 6.5 0.94 9.3 0.2 2.7 2 1 1 3 3 3 0 Fatty acid desaturase AA_permease_2 PF13520.6 EGO55890.1 - 1.7e-49 168.8 53.3 2.1e-49 168.5 53.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO55890.1 - 1.5e-22 79.9 49.6 1.9e-22 79.6 49.6 1.0 1 0 0 1 1 1 1 Amino acid permease UCH PF00443.29 EGO55891.1 - 1.4e-37 129.6 0.0 2e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EGO55891.1 - 1.4e-25 88.8 1.5 3.1e-24 84.5 0.1 2.5 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 EGO55891.1 - 1.3e-23 83.0 12.6 1.8e-19 69.8 1.7 3.2 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EGO55891.1 - 7.3e-20 71.8 4.6 1.1e-17 64.7 0.0 3.8 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 EGO55891.1 - 3.9e-16 58.6 0.1 2.4e-08 33.7 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain zf-C2H2_11 PF16622.5 EGO55891.1 - 2.8 7.8 6.6 36 4.2 0.3 3.8 3 0 0 3 3 3 0 zinc-finger C2H2-type NifU_N PF01592.16 EGO55892.1 - 1.1e-55 187.3 0.0 1.4e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 EGO55892.1 - 0.04 14.2 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 TSCPD domain DUF1858 PF08984.11 EGO55892.1 - 0.1 12.8 0.1 0.35 11.1 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1858) Striatin PF08232.12 EGO55893.1 - 0.0062 17.1 3.1 0.0062 17.1 3.1 3.0 2 1 0 2 2 2 1 Striatin family CPSF100_C PF13299.6 EGO55893.1 - 0.014 15.5 2.0 0.014 15.5 2.0 3.0 3 1 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal DUF16 PF01519.16 EGO55893.1 - 0.026 15.0 3.8 0.4 11.2 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 PAS_10 PF13596.6 EGO55893.1 - 0.054 14.1 0.4 0.58 10.8 0.1 2.3 2 0 0 2 2 2 0 PAS domain Cnn_1N PF07989.11 EGO55893.1 - 0.072 13.3 5.8 0.13 12.4 2.8 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Fib_alpha PF08702.10 EGO55893.1 - 0.25 11.5 1.9 11 6.2 0.1 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2052 PF09747.9 EGO55893.1 - 0.37 10.9 28.9 0.091 12.9 9.0 2.9 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Paf1 PF03985.13 EGO55893.1 - 0.45 9.5 31.4 1.3 8.0 11.8 2.4 2 0 0 2 2 2 0 Paf1 Mit_KHE1 PF10173.9 EGO55893.1 - 1.7 8.7 3.1 1.5 8.8 1.3 1.8 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related UBN_AB PF14075.6 EGO55893.1 - 2.6 7.7 14.9 2 8.1 3.5 2.9 3 0 0 3 3 3 0 Ubinuclein conserved middle domain V_ATPase_I PF01496.19 EGO55893.1 - 4.4 5.1 13.3 4 5.2 1.8 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF913 PF06025.12 EGO55893.1 - 5.8 5.8 11.7 5.7 5.8 1.3 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) GST_N PF02798.20 EGO55894.1 - 4.1e-13 49.5 0.0 7.5e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO55894.1 - 1.4e-11 44.7 0.0 2.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO55894.1 - 1.4e-10 41.2 0.1 2.2e-10 40.6 0.1 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGO55894.1 - 1.3e-09 38.2 0.1 4.1e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO55894.1 - 1.1e-08 35.0 0.0 2.4e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO55894.1 - 1.4e-08 34.9 0.0 2.6e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EGO55894.1 - 0.076 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein HORMA PF02301.18 EGO55895.1 - 2e-33 115.8 0.0 2.4e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EGO55895.1 - 0.003 17.5 0.4 0.012 15.6 0.4 2.1 1 1 0 1 1 1 1 Autophagy-related protein 101 BUD22 PF09073.10 EGO55895.1 - 0.011 15.2 0.3 0.012 15.0 0.3 1.1 1 0 0 1 1 1 0 BUD22 DUF2660 PF10859.8 EGO55895.1 - 0.067 13.7 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) DEAD PF00270.29 EGO55896.1 - 1.4e-48 165.0 0.0 9.6e-48 162.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO55896.1 - 2.5e-33 114.7 0.0 5.7e-32 110.4 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EGO55896.1 - 1.3e-05 24.2 0.0 5.6e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SOBP PF15279.6 EGO55896.1 - 8.7 6.9 17.4 13 6.3 17.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Rft-1 PF04506.13 EGO55897.1 - 5.5e-139 464.2 0.0 7.2e-139 463.8 0.0 1.1 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 EGO55897.1 - 3.7e-06 26.4 14.0 0.0025 17.1 0.1 4.3 4 0 0 4 4 4 3 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 EGO55897.1 - 0.0069 15.8 16.0 3.7 6.8 16.0 3.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein SPX PF03105.19 EGO55897.1 - 1.2 9.0 4.1 4.4 7.1 4.2 1.8 1 1 0 1 1 1 0 SPX domain TMEM51 PF15345.6 EGO55898.1 - 0.93 9.3 8.2 1.1 9.1 8.2 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 DUF508 PF04370.12 EGO55898.1 - 5 6.8 6.9 19 5.0 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF508) CBM_10 PF02013.16 EGO55899.1 - 0.012 16.1 2.3 2.7 8.5 0.2 2.3 2 0 0 2 2 2 0 Cellulose or protein binding domain TRP PF06011.12 EGO55900.1 - 2.6e-151 504.2 30.3 3.2e-151 503.9 30.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EGO55900.1 - 1.5e-39 135.6 0.0 2.5e-39 134.8 0.0 1.4 1 0 0 1 1 1 1 ML-like domain LapA_dom PF06305.11 EGO55900.1 - 0.01 15.7 0.4 0.01 15.7 0.4 2.6 3 0 0 3 3 3 1 Lipopolysaccharide assembly protein A domain DUF3579 PF12112.8 EGO55903.1 - 0.079 13.5 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) Codanin-1_C PF15296.6 EGO55903.1 - 0.27 11.3 6.3 0.63 10.1 6.3 1.6 1 0 0 1 1 1 0 Codanin-1 C-terminus Glyco_hydro_16 PF00722.21 EGO55905.1 - 2.5e-13 49.9 0.0 9.2e-13 48.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EGO55905.1 - 6.7e-05 21.5 0.6 0.14 10.6 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) PHY PF00360.20 EGO55906.1 - 1e-25 90.1 0.0 1.9e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Phytochrome region GAF PF01590.26 EGO55906.1 - 9.1e-18 65.2 0.0 2.5e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain HATPase_c PF02518.26 EGO55906.1 - 2.6e-15 56.9 0.1 4.7e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGO55906.1 - 9.7e-14 51.5 0.0 2.2e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGO55906.1 - 9.5e-07 28.8 0.1 5.7e-06 26.3 0.2 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 EGO55906.1 - 0.00062 20.4 0.0 0.0017 19.0 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 EGO55906.1 - 0.077 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EGO55906.1 - 0.077 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain LisH PF08513.11 EGO55907.1 - 0.076 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 LisH TRADD_N PF09034.10 EGO55911.1 - 0.016 15.2 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 TRADD, N-terminal domain TRAPP PF04051.16 EGO55912.1 - 5.8e-35 120.1 0.1 7e-35 119.9 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.32 EGO55913.1 - 3.3e-37 125.8 5.8 7.3e-08 33.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO55913.1 - 1.1e-13 51.3 0.1 0.0022 18.2 0.0 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGO55913.1 - 0.049 13.0 0.0 5.6 6.2 0.1 2.8 2 1 1 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 EGO55913.1 - 0.069 12.1 0.0 3.2 6.6 0.0 2.4 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Retro_M PF02813.14 EGO55913.1 - 0.11 12.9 0.1 20 5.6 0.0 3.2 2 1 1 3 3 3 0 Retroviral M domain Form_Nir_trans PF01226.17 EGO55914.1 - 0.019 14.3 1.1 0.028 13.8 1.1 1.1 1 0 0 1 1 1 0 Formate/nitrite transporter Apt1 PF10351.9 EGO55914.1 - 0.44 9.3 11.8 0.89 8.3 2.8 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain SP_C-Propep PF08999.10 EGO55915.1 - 0.0036 17.0 2.7 0.0048 16.6 2.7 1.2 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide Protocadherin PF08374.11 EGO55915.1 - 0.053 13.5 0.0 0.053 13.5 0.0 1.1 1 0 0 1 1 1 0 Protocadherin DUF3176 PF11374.8 EGO55916.1 - 5e-36 123.2 2.0 1.9e-35 121.3 0.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF3382 PF11862.8 EGO55916.1 - 1.9 8.8 9.1 1.7 9.0 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) DUF4781 PF16013.5 EGO55916.1 - 4.5 6.0 6.0 0.81 8.4 0.2 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4781) MARVEL PF01284.23 EGO55916.1 - 7.9 6.5 10.5 0.85 9.6 0.1 2.8 3 0 0 3 3 3 0 Membrane-associating domain HA2 PF04408.23 EGO55917.1 - 6.1e-15 55.4 1.9 1.9e-14 53.8 0.0 2.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGO55917.1 - 1.7e-13 50.9 0.0 4e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO55917.1 - 1.9e-10 40.8 0.0 4.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EGO55917.1 - 3.9e-09 36.8 0.0 9.5e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 EGO55917.1 - 8.2e-08 32.6 0.9 8.1e-07 29.4 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 EGO55917.1 - 0.0091 16.5 3.4 0.55 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGO55917.1 - 0.019 15.5 0.2 0.066 13.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 EGO55917.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 EGO55917.1 - 0.057 13.3 0.1 0.44 10.5 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase PF06745.13 EGO55917.1 - 0.075 12.4 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 KaiC DUF3395 PF11875.8 EGO55917.1 - 9.4 6.1 9.8 0.16 11.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) Gcn1_N PF12074.8 EGO55918.1 - 2.8e-121 405.2 0.7 2.8e-121 405.2 0.7 3.6 3 0 0 3 3 3 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT_EZ PF13513.6 EGO55918.1 - 5.9e-31 106.5 54.7 6.2e-07 29.8 0.0 21.0 19 3 6 25 25 21 6 HEAT-like repeat HEAT PF02985.22 EGO55918.1 - 6.6e-31 103.7 44.0 0.045 14.0 0.1 23.9 28 0 0 28 28 25 8 HEAT repeat HEAT_2 PF13646.6 EGO55918.1 - 2e-30 105.0 62.0 3.4e-05 24.1 0.1 17.7 14 4 8 22 22 21 9 HEAT repeats Vac14_Fab1_bd PF12755.7 EGO55918.1 - 6.1e-16 58.8 1.0 1.1 9.9 0.0 9.4 8 1 0 8 8 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGO55918.1 - 1.3e-15 57.8 8.4 0.31 11.1 0.3 11.3 7 3 5 12 12 12 4 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGO55918.1 - 4.1e-15 56.0 0.0 0.013 15.1 0.0 6.7 5 1 1 6 6 6 4 CLASP N terminal ParcG PF10274.9 EGO55918.1 - 5.7e-13 49.4 3.0 0.00029 21.0 0.0 6.3 5 2 1 6 6 6 3 Parkin co-regulated protein Adaptin_N PF01602.20 EGO55918.1 - 6.2e-11 41.5 10.3 0.041 12.5 0.3 8.4 5 3 3 8 8 8 3 Adaptin N terminal region UME PF08064.13 EGO55918.1 - 3.4e-09 36.5 5.9 4.8 7.2 0.0 9.0 8 2 1 10 10 9 2 UME (NUC010) domain IFRD PF05004.13 EGO55918.1 - 2.5e-05 23.6 3.6 2.5e-05 23.6 3.6 5.5 8 0 0 8 8 8 1 Interferon-related developmental regulator (IFRD) DUF937 PF06078.11 EGO55918.1 - 5.7e-05 23.7 1.8 9.7 6.8 0.0 6.4 6 1 0 6 6 5 0 Bacterial protein of unknown function (DUF937) Tti2 PF10521.9 EGO55918.1 - 9.7e-05 22.0 3.4 0.012 15.2 0.0 4.9 6 0 0 6 6 4 1 Tti2 family TIP120 PF08623.10 EGO55918.1 - 0.0001 22.1 0.5 0.092 12.5 0.0 5.6 6 1 0 6 6 4 1 TATA-binding protein interacting (TIP20) DUF3385 PF11865.8 EGO55918.1 - 0.00018 21.4 0.6 3.2 7.6 0.0 6.4 6 2 2 8 8 8 1 Domain of unknown function (DUF3385) FANCI_S2 PF14676.6 EGO55918.1 - 0.0005 20.4 0.8 1.7 8.9 0.0 5.0 4 0 0 4 4 4 1 FANCI solenoid 2 RIX1 PF08167.12 EGO55918.1 - 0.00077 19.3 3.8 0.1 12.4 0.2 5.3 4 1 0 4 4 4 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 EGO55918.1 - 0.0017 17.5 27.4 0.0037 16.4 1.6 8.0 5 3 4 10 10 10 2 RNAPII transcription regulator C-terminal TFCD_C PF12612.8 EGO55918.1 - 0.0073 16.2 0.6 0.083 12.7 0.0 3.3 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal Pes-10 PF07149.11 EGO55918.1 - 0.0086 15.2 1.2 0.018 14.1 0.1 2.0 2 0 0 2 2 2 1 Pes-10 Ipi1_N PF12333.8 EGO55918.1 - 0.11 13.1 0.1 5.5 7.6 0.0 3.8 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Cohesin_HEAT PF12765.7 EGO55918.1 - 0.39 11.1 2.8 16 5.9 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion Arm PF00514.23 EGO55918.1 - 0.41 10.8 12.4 97 3.2 0.0 9.4 10 1 2 12 12 11 0 Armadillo/beta-catenin-like repeat U3snoRNP10 PF12397.8 EGO55918.1 - 8.9 6.7 17.9 14 6.0 0.3 6.8 7 1 0 7 7 4 0 U3 small nucleolar RNA-associated protein 10 Ribosomal_L19e PF01280.20 EGO55919.1 - 7.6e-61 204.4 6.7 7.6e-61 204.4 6.7 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e SHMT PF00464.19 EGO55920.1 - 1.3e-194 646.4 0.0 1.6e-194 646.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 EGO55920.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family 2OG-FeII_Oxy_2 PF13532.6 EGO55921.1 - 3.6e-29 102.4 0.0 8.8e-29 101.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 EGO55921.1 - 7.7e-23 81.6 0.3 3.7e-22 79.3 0.0 2.3 2 1 0 2 2 2 1 Isochorismatase family GST_C_2 PF13410.6 EGO55921.1 - 0.016 15.2 0.0 0.051 13.6 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3678 PF12435.8 EGO55921.1 - 0.049 13.0 3.2 0.16 11.3 3.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) LRR_8 PF13855.6 EGO55922.1 - 1.4e-23 82.4 3.3 7.1e-10 38.5 0.6 3.7 2 1 2 4 4 4 3 Leucine rich repeat Pkinase_Tyr PF07714.17 EGO55922.1 - 1.5e-15 57.2 0.0 3.8e-13 49.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.7 EGO55922.1 - 1.2e-14 54.1 3.9 2e-06 28.1 0.3 5.0 4 2 0 5 5 5 3 Leucine Rich repeats (2 copies) Pkinase PF00069.25 EGO55922.1 - 6.1e-11 42.2 0.0 1.6e-09 37.5 0.0 2.5 1 1 1 2 2 2 1 Protein kinase domain Kdo PF06293.14 EGO55922.1 - 2.5e-05 23.7 0.1 4.4e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_9 PF14580.6 EGO55922.1 - 8.1e-05 22.2 0.1 0.037 13.5 0.0 2.4 1 1 0 2 2 2 2 Leucine-rich repeat GvpK PF05121.12 EGO55922.1 - 0.027 14.5 0.7 0.073 13.1 0.7 1.8 1 0 0 1 1 1 0 Gas vesicle protein K LRR_5 PF13306.6 EGO55922.1 - 0.043 13.8 0.0 0.17 11.9 0.0 1.8 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) Cbl_N PF02262.16 EGO55922.1 - 0.14 12.2 0.0 0.52 10.3 0.0 1.8 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 LRR_1 PF00560.33 EGO55922.1 - 4.2 8.3 10.7 44 5.2 0.2 5.2 5 1 0 5 5 5 0 Leucine Rich Repeat Bromo_TP PF07524.13 EGO55923.1 - 1.7e-22 79.2 0.0 3e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 EGO55923.1 - 6.4e-12 45.8 4.6 2.1e-06 28.2 1.6 2.9 2 0 0 2 2 2 2 Transcription factor TFIID complex subunit 8 C-term WD40 PF00400.32 EGO55924.1 - 4.1e-45 150.8 22.8 2.7e-08 34.3 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO55924.1 - 5.7e-09 36.1 0.6 0.11 12.8 0.0 4.5 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO55924.1 - 0.00054 18.7 3.6 0.054 12.1 0.1 3.9 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGO55924.1 - 0.0037 16.3 0.0 9.2 5.1 0.0 3.8 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGO55924.1 - 0.0065 15.8 0.0 0.43 9.8 0.0 2.6 2 1 0 3 3 3 1 WD40-like domain PD40 PF07676.12 EGO55924.1 - 0.01 15.8 0.6 22 5.1 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat TMEM154 PF15102.6 EGO55925.1 - 0.0035 17.2 1.2 0.0065 16.4 1.2 1.4 1 1 0 1 1 1 1 TMEM154 protein family NicO PF03824.16 EGO55925.1 - 0.03 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein LEA_3 PF03242.13 EGO55925.1 - 0.073 13.8 0.2 0.25 12.1 0.0 1.8 2 0 0 2 2 2 0 Late embryogenesis abundant protein DUF4381 PF14316.6 EGO55925.1 - 0.11 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CcmD PF04995.14 EGO55925.1 - 0.67 10.1 3.5 1.2 9.3 3.5 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Shisa PF13908.6 EGO55925.1 - 3.7 7.7 7.1 2.5 8.3 0.1 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF3112 PF11309.8 EGO55926.1 - 0.36 10.2 3.9 0.49 9.8 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Ribosomal_L22 PF00237.19 EGO55927.1 - 2.7e-23 82.1 0.4 2.7e-23 82.1 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e DUF3776 PF12618.8 EGO55927.1 - 1.2 9.7 7.0 0.33 11.5 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3776) CFEM PF05730.11 EGO55928.1 - 1.5e-11 44.2 11.1 2.4e-11 43.5 11.1 1.3 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 EGO55928.1 - 0.0026 17.1 2.6 0.0057 16.0 2.6 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain COX6C PF02937.15 EGO55929.1 - 0.0066 16.5 0.0 0.0083 16.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc XylR_N PF06505.11 EGO55929.1 - 0.12 12.1 0.1 0.13 12.0 0.1 1.0 1 0 0 1 1 1 0 Activator of aromatic catabolism Hydrolase_6 PF13344.6 EGO55931.1 - 1.3e-22 79.8 0.0 2.5e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO55931.1 - 6.3e-11 42.2 0.0 7.5e-10 38.7 0.0 2.6 2 1 0 2 2 2 1 HAD-hyrolase-like Glyco_hydro_125 PF06824.11 EGO55932.1 - 1.9e-175 583.7 0.0 2.2e-175 583.5 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Amnionless PF14828.6 EGO55933.1 - 0.048 12.5 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 EGO55933.1 - 0.13 13.2 0.1 0.34 11.8 0.1 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pex14_N PF04695.13 EGO55933.1 - 2.7 8.7 25.9 0.77 10.4 6.2 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1100 PF06500.11 EGO55934.1 - 1.6e-13 50.2 0.0 1.1e-11 44.3 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 EGO55934.1 - 6.7e-08 33.4 1.3 1.4e-07 32.4 0.2 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO55934.1 - 2.2e-06 27.5 0.1 4.8e-06 26.4 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGO55934.1 - 0.00013 21.8 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EGO55934.1 - 0.00015 21.1 0.1 0.00027 20.3 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGO55934.1 - 0.00047 19.7 0.1 0.0011 18.5 0.1 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EGO55934.1 - 0.0046 16.6 0.2 0.012 15.2 0.2 1.7 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 EGO55934.1 - 0.0064 16.1 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) TPR_12 PF13424.6 EGO55934.1 - 0.028 14.7 0.7 0.077 13.3 0.3 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_23 PF13489.6 EGO55935.1 - 0.0001 22.2 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO55935.1 - 0.0017 19.1 0.0 0.011 16.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Serglycin PF04360.12 EGO55935.1 - 0.74 9.7 4.8 2.4 8.1 0.0 2.6 3 0 0 3 3 3 0 Serglycin PDGF_N PF04692.13 EGO55936.1 - 7.3 7.4 7.5 12 6.7 7.5 1.3 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region HET PF06985.11 EGO55937.1 - 1.8e-20 73.8 0.0 5.1e-20 72.3 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Plasmodium_Vir PF05795.11 EGO55940.1 - 0.001 18.6 2.4 0.011 15.2 2.4 2.3 1 1 0 1 1 1 1 Plasmodium vivax Vir protein Adeno_E3_CR2 PF02439.15 EGO55940.1 - 0.013 15.2 0.2 0.023 14.4 0.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ERGIC_N PF13850.6 EGO55940.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Amidohydro_3 PF07969.11 EGO55943.1 - 3.9e-15 56.3 1.2 4.4e-10 39.6 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 EGO55943.1 - 3.7e-10 39.7 0.0 2.4e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family bMG10 PF17973.1 EGO55943.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain AA_permease PF00324.21 EGO55945.1 - 1.8e-142 475.3 36.1 2.3e-142 475.0 36.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO55945.1 - 2.8e-38 131.9 35.9 3.5e-38 131.5 35.9 1.1 1 0 0 1 1 1 1 Amino acid permease Claudin_3 PF06653.11 EGO55945.1 - 0.47 10.4 21.2 1.2 9.1 1.0 4.0 2 2 2 4 4 4 0 Tight junction protein, Claudin-like DUF997 PF06196.12 EGO55945.1 - 4.3 7.4 10.9 14 5.8 1.2 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF997) Methyltransf_23 PF13489.6 EGO55946.1 - 1.2e-15 57.8 0.0 1.8e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO55946.1 - 8.2e-11 42.5 0.0 2.5e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO55946.1 - 5.4e-10 39.8 0.0 1.1e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO55946.1 - 1.2e-07 32.4 0.0 6.1e-07 30.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO55946.1 - 2.6e-05 24.1 0.0 0.14 11.9 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Ubie_methyltran PF01209.18 EGO55946.1 - 6.7e-05 22.3 0.0 0.0018 17.7 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EGO55946.1 - 0.00043 20.4 0.0 0.0011 19.1 0.0 1.6 1 1 1 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 EGO55946.1 - 0.088 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 EGO55946.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.6 EGO55947.1 - 2.7e-20 72.9 0.0 3.9e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO55947.1 - 2.5e-11 44.1 0.0 6.2e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO55947.1 - 4.8e-10 40.0 0.0 1.1e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO55947.1 - 3.3e-09 37.4 0.0 1.3e-08 35.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO55947.1 - 4.2e-07 29.9 0.0 9.7e-06 25.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO55947.1 - 0.00063 19.1 0.0 0.0084 15.5 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EGO55947.1 - 0.013 15.3 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 EGO55947.1 - 0.015 14.6 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 EGO55947.1 - 0.024 14.1 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 EGO55947.1 - 0.04 13.5 0.0 0.1 12.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.13 EGO55947.1 - 0.079 12.3 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Mo-co_dimer PF03404.16 EGO55948.1 - 5.8e-09 36.1 0.0 9.6e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 EGO55948.1 - 3.3e-08 33.8 0.0 6.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Thioredoxin_2 PF13098.6 EGO55948.1 - 0.028 14.9 0.0 0.086 13.3 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like domain Ank_2 PF12796.7 EGO55950.1 - 3.8e-15 56.2 0.1 7.6e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGO55950.1 - 8.7e-15 54.6 0.9 8.4e-08 32.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGO55950.1 - 6.9e-12 45.7 0.2 1.6e-11 44.5 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGO55950.1 - 7.3e-12 45.2 0.8 0.00017 21.9 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGO55950.1 - 4.1e-11 42.1 0.2 0.00034 20.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat CorA PF01544.18 EGO55950.1 - 0.11 11.8 0.5 0.23 10.7 0.5 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HU-CCDC81_bac_1 PF18174.1 EGO55950.1 - 0.15 11.9 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 Glyco_hydro_47 PF01532.20 EGO55952.1 - 6.5e-171 569.2 0.0 7.7e-171 569.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SOG2 PF10428.9 EGO55954.1 - 0.0044 16.3 42.2 0.0061 15.8 42.2 1.3 1 0 0 1 1 1 1 RAM signalling pathway protein DUF4551 PF15087.6 EGO55954.1 - 2.6 6.8 23.4 3.6 6.3 23.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SHR-BD PF06650.12 EGO55955.1 - 2.1e-98 329.0 0.0 1.2e-96 323.2 0.0 2.8 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 EGO55955.1 - 7.1e-97 323.5 11.5 7e-93 310.4 1.0 5.9 6 1 1 7 7 7 2 Repeating coiled region of VPS13 VPS13 PF16908.5 EGO55955.1 - 3.1e-85 285.7 2.6 1.9e-83 279.9 0.0 3.7 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EGO55955.1 - 6.2e-76 254.1 5.5 1.6e-70 236.5 0.4 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EGO55955.1 - 5.5e-42 142.6 0.1 2e-41 140.7 0.1 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EGO55955.1 - 1.7e-07 31.5 0.0 5.8e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DUF3429 PF11911.8 EGO55956.1 - 3.4e-44 150.6 7.6 4.5e-44 150.2 7.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF4407 PF14362.6 EGO55956.1 - 0.073 12.4 1.7 0.085 12.2 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1682 PF07946.14 EGO55956.1 - 2.2 7.4 19.0 3.3 6.8 19.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Zip PF02535.22 EGO55956.1 - 2.5 7.2 6.6 4.5 6.4 6.6 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter HET PF06985.11 EGO55958.1 - 1.4e-25 90.3 0.0 3.5e-25 89.1 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_23 PF13489.6 EGO55959.1 - 1.5e-19 70.4 0.0 2.2e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO55959.1 - 1.2e-10 41.9 0.0 4.1e-10 40.2 0.0 1.9 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO55959.1 - 2.1e-09 37.9 0.0 4.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO55959.1 - 5.3e-07 30.3 0.0 3.1e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO55959.1 - 1.5e-05 24.9 0.0 0.00032 20.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO55959.1 - 0.0013 18.1 0.0 0.013 14.9 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EGO55959.1 - 0.0019 17.7 0.0 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.9 EGO55959.1 - 0.004 16.9 0.0 0.0061 16.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EGO55959.1 - 0.022 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_PK PF05891.12 EGO55959.1 - 0.027 14.0 0.1 0.077 12.5 0.1 1.7 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase PrmA PF06325.13 EGO55959.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EGO55959.1 - 0.17 12.0 0.0 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 EGO55960.1 - 3.5e-17 62.7 0.0 5.2e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO55960.1 - 1.4e-09 38.5 0.0 3.6e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO55960.1 - 1.3e-08 35.4 0.0 2.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO55960.1 - 3.6e-05 24.4 0.0 0.00017 22.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO55960.1 - 7.3e-05 22.6 0.0 0.0013 18.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGO55960.1 - 0.004 16.9 0.0 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 EGO55960.1 - 0.0053 16.1 0.0 0.067 12.5 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EGO55960.1 - 0.017 14.6 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 EGO55960.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 EGO55960.1 - 0.11 12.4 0.0 10 5.9 0.0 2.9 3 0 0 3 3 3 0 Hypothetical methyltransferase Ammonium_transp PF00909.21 EGO55961.1 - 2.1e-103 346.1 15.4 2.4e-103 345.9 15.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3267 PF11667.8 EGO55961.1 - 0.069 13.4 0.2 0.069 13.4 0.2 4.1 4 1 1 5 5 5 0 Putative zincin peptidase Comm PF15957.5 EGO55961.1 - 0.49 10.8 1.8 0.9 9.9 0.1 2.2 2 0 0 2 2 2 0 Commissureless AvrLm4-7 PF18661.1 EGO55963.1 - 0.0053 17.8 0.2 0.01 16.9 0.2 1.4 1 0 0 1 1 1 1 Avirulence Effector AvrLm4-7 Peptidase_U49 PF10463.9 EGO55963.1 - 0.046 13.5 0.0 0.25 11.1 0.0 2.0 1 1 1 2 2 2 0 Peptidase U49 DUF1479 PF07350.12 EGO55964.1 - 2.7e-158 527.1 0.0 3.4e-158 526.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) p450 PF00067.22 EGO55965.1 - 2.2e-42 145.4 0.0 2.6e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGO55966.1 - 1.5e-50 172.3 0.0 2.5e-49 168.3 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 IL32 PF15225.6 EGO55966.1 - 0.32 11.4 1.0 1.1 9.7 0.1 2.4 2 1 0 2 2 2 0 Interleukin 32 Pyr_redox_2 PF07992.14 EGO55967.1 - 4.6e-51 173.8 1.3 6.3e-51 173.4 1.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EGO55967.1 - 1.6e-14 53.6 0.0 3.9e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 EGO55967.1 - 4.6e-14 52.7 0.6 7.1e-11 42.5 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 EGO55967.1 - 6.3e-07 29.9 0.0 1.9e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_9 PF13454.6 EGO55967.1 - 0.0017 18.4 1.8 0.48 10.4 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding AMP-binding PF00501.28 EGO55968.1 - 4.2e-75 252.9 0.1 5e-75 252.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO55968.1 - 5.9e-15 56.0 1.9 1.1e-14 55.1 1.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PG_isomerase_N PF18353.1 EGO55968.1 - 0.00061 20.2 0.4 0.035 14.5 0.1 2.5 2 0 0 2 2 2 1 Phosphoglucose isomerase N-terminal domain Polysacc_lyase PF14099.6 EGO55969.1 - 2.6e-54 184.3 6.8 2.9e-54 184.1 6.8 1.0 1 0 0 1 1 1 1 Polysaccharide lyase Sugar_tr PF00083.24 EGO55970.1 - 1.6e-77 261.3 26.7 1.8e-77 261.2 26.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO55970.1 - 6.1e-27 94.5 26.4 7.1e-25 87.7 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGO55970.1 - 6.1e-07 28.2 2.2 9.9e-07 27.5 2.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EGO55970.1 - 9.1e-06 24.5 1.3 9.1e-06 24.5 1.3 2.8 2 2 0 2 2 2 1 MFS/sugar transport protein Methyltransf_2 PF00891.18 EGO55973.1 - 2e-21 76.3 0.0 3.4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MarR_2 PF12802.7 EGO55973.1 - 0.0016 18.3 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 MarR family Methyltransf_25 PF13649.6 EGO55973.1 - 0.048 14.4 0.0 0.47 11.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain HTH_27 PF13463.6 EGO55973.1 - 0.14 12.6 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain Ank_4 PF13637.6 EGO55974.1 - 2e-37 127.0 6.4 1.8e-05 25.2 0.1 11.0 9 2 2 11 11 11 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO55974.1 - 1e-36 125.3 3.0 6.7e-10 39.4 0.0 8.0 5 2 3 8 8 8 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGO55974.1 - 2.4e-32 110.6 0.6 1.7e-06 28.2 0.0 10.0 9 1 0 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO55974.1 - 6.7e-29 96.7 16.8 0.0022 18.3 0.0 13.3 14 1 0 14 14 14 7 Ankyrin repeat Ank PF00023.30 EGO55974.1 - 1.1e-21 76.3 11.8 0.1 13.1 0.4 10.7 11 0 0 11 11 11 7 Ankyrin repeat F-box-like PF12937.7 EGO55974.1 - 0.0032 17.3 0.3 0.017 15.0 0.1 2.3 2 0 0 2 2 2 1 F-box-like PGA2 PF07543.12 EGO55974.1 - 1.5 8.8 8.1 0.44 10.5 1.3 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Voldacs PF03517.13 EGO55974.1 - 3.7 7.7 6.6 1.8 8.7 1.9 2.6 3 0 0 3 3 3 0 Regulator of volume decrease after cellular swelling NOA36 PF06524.12 EGO55974.1 - 4.1 6.7 8.4 9.1 5.5 8.4 1.5 1 0 0 1 1 1 0 NOA36 protein HET PF06985.11 EGO55975.1 - 1.2e-30 106.8 0.4 1.4e-29 103.4 0.0 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Usp PF00582.26 EGO55975.1 - 0.042 14.4 0.5 0.07 13.6 0.5 1.3 1 0 0 1 1 1 0 Universal stress protein family An_peroxidase PF03098.15 EGO55976.1 - 2.1e-40 138.8 0.0 3.6e-24 85.2 0.0 4.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 EGO55976.1 - 3.8e-05 22.6 0.0 0.0045 15.8 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF2235 PF09994.9 EGO55977.1 - 7e-95 317.7 0.2 7e-95 317.7 0.2 1.9 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Dscam_C PF12355.8 EGO55978.1 - 0.061 14.3 0.6 0.11 13.5 0.6 1.4 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal WXG100 PF06013.12 EGO55978.1 - 0.07 13.4 1.9 0.16 12.2 1.9 1.6 1 0 0 1 1 1 0 Proteins of 100 residues with WXG AAA_12 PF13087.6 EGO55979.1 - 4e-35 121.3 0.0 7.3e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGO55979.1 - 9.4e-21 74.8 1.2 2.1e-19 70.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGO55979.1 - 5.4e-07 30.0 0.2 5.7e-06 26.7 0.0 2.7 3 1 0 3 3 3 1 AAA domain DUF2075 PF09848.9 EGO55979.1 - 3.4e-06 26.6 1.7 0.006 15.9 0.0 2.6 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EGO55979.1 - 0.00076 19.2 0.3 0.0063 16.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 EGO55979.1 - 0.029 14.4 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EGO55979.1 - 0.038 13.5 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EGO55979.1 - 0.048 13.9 0.0 0.98 9.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGO55979.1 - 0.077 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein zf_CCCH_4 PF18345.1 EGO55979.1 - 0.3 11.2 8.4 0.016 15.3 2.1 2.4 2 0 0 2 2 2 0 Zinc finger domain MFS_1 PF07690.16 EGO55980.1 - 2e-27 96.1 40.6 2e-26 92.8 37.0 3.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO55980.1 - 9.8e-13 47.4 5.4 2.5e-09 36.1 2.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) AAA PF00004.29 EGO55981.1 - 6.3e-10 39.6 0.0 1.5e-09 38.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 EGO55981.1 - 0.04 13.6 0.2 0.35 10.5 0.0 2.1 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_lid_6 PF17866.1 EGO55981.1 - 0.041 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA lid domain Terminase_6C PF17289.2 EGO55983.1 - 0.032 14.3 0.4 0.065 13.3 0.4 1.6 1 0 0 1 1 1 0 Terminase RNaseH-like domain TRPM_tetra PF16519.5 EGO55983.1 - 0.62 10.2 5.2 0.29 11.3 2.7 1.7 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DUF2794 PF10984.8 EGO55985.1 - 0.051 13.7 1.2 1.1 9.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2794) Myb_DNA-bind_6 PF13921.6 EGO55986.1 - 0.18 12.1 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF4229 PF14012.6 EGO55988.1 - 0.026 14.6 5.4 0.026 14.6 5.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) Metaviral_G PF09595.10 EGO55989.1 - 0.018 15.1 0.8 0.028 14.5 0.8 1.3 1 0 0 1 1 1 0 Metaviral_G glycoprotein OTT_1508_deam PF14441.6 EGO55991.1 - 9.5e-19 67.2 0.1 2e-18 66.1 0.1 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase EAR PF07897.11 EGO55991.1 - 0.67 9.6 4.2 0.93 9.2 2.4 2.1 2 0 0 2 2 2 0 Ethylene-responsive binding factor-associated repression Alpha-amylase PF00128.24 EGO55993.1 - 2e-19 70.4 0.0 5.8e-19 68.8 0.0 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 EGO55993.1 - 0.0044 15.3 0.1 2.1 6.5 0.0 2.7 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 PNMA PF14893.6 EGO55993.1 - 0.052 13.0 0.1 6.1 6.1 0.0 2.1 2 0 0 2 2 2 0 PNMA VIT1 PF01988.19 EGO55994.1 - 5.6e-64 215.9 3.5 7.1e-64 215.6 3.5 1.1 1 0 0 1 1 1 1 VIT family Orai-1 PF07856.12 EGO55994.1 - 0.093 12.4 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Mediator of CRAC channel activity ADSL_C PF10397.9 EGO55994.1 - 0.097 13.2 0.8 0.35 11.4 0.1 2.0 1 1 1 2 2 2 0 Adenylosuccinate lyase C-terminus Ribosomal_L12_N PF16320.5 EGO55994.1 - 0.15 11.8 0.1 0.15 11.8 0.1 1.6 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain p450 PF00067.22 EGO55995.1 - 5.2e-59 200.2 0.1 9.5e-46 156.5 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 Abhydrolase_1 PF00561.20 EGO55996.1 - 0.057 13.0 0.0 0.06 13.0 0.0 1.0 1 0 0 1 1 1 0 alpha/beta hydrolase fold BRO1 PF03097.18 EGO55998.1 - 4.4e-121 404.3 0.0 7.2e-121 403.6 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EGO55998.1 - 2.5e-83 279.8 5.1 2.5e-83 279.8 5.1 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF3829 PF12889.7 EGO55998.1 - 0.0051 16.3 0.7 0.012 15.2 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) zf-C4H2 PF10146.9 EGO55998.1 - 0.017 15.4 2.1 0.074 13.3 2.1 2.1 1 0 0 1 1 1 0 Zinc finger-containing protein K-box PF01486.17 EGO55998.1 - 0.054 13.7 0.1 0.054 13.7 0.1 2.8 3 0 0 3 3 3 0 K-box region SUIM_assoc PF16619.5 EGO55998.1 - 0.3 11.2 4.5 2.4 8.3 0.1 3.5 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 UPF0242 PF06785.11 EGO55998.1 - 3.7 7.6 6.7 28 4.8 1.9 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF4355 PF14265.6 EGO55998.1 - 8.7 6.6 11.0 6.4 7.0 6.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Fringe PF02434.16 EGO55999.1 - 8e-08 32.0 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 EGO55999.1 - 1.6e-06 27.7 0.0 5.2e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF604 CAF1A PF12253.8 EGO55999.1 - 0.8 9.9 6.9 6.1 7.1 0.0 3.8 3 1 1 4 4 4 0 Chromatin assembly factor 1 subunit A Ysc84 PF04366.12 EGO56001.1 - 4.7e-53 178.3 0.0 7.9e-53 177.6 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Cellulase PF00150.18 EGO56002.1 - 9.4e-21 74.5 2.7 2.4e-20 73.1 2.7 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mpv17_PMP22 PF04117.12 EGO56002.1 - 0.061 13.5 0.4 1.8 8.8 0.1 3.0 3 0 0 3 3 3 0 Mpv17 / PMP22 family Bac_luciferase PF00296.20 EGO56003.1 - 8.1e-59 199.6 0.0 1.2e-58 199.1 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 EGO56004.1 - 4.2e-30 104.9 31.5 5.5e-30 104.5 31.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FMO-like PF00743.19 EGO56007.1 - 8.4e-14 50.9 0.1 5.1e-12 45.0 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGO56007.1 - 1.1e-09 38.0 0.0 4e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO56007.1 - 1.8e-09 37.6 0.0 5.4e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGO56007.1 - 8.2e-09 35.1 0.0 1.2e-07 31.3 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO56007.1 - 1.9e-07 30.6 0.1 3.2e-05 23.2 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGO56007.1 - 0.00056 19.9 0.1 1 9.3 0.0 3.8 3 1 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 EGO56007.1 - 0.00072 19.2 1.6 0.9 9.0 0.1 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 EGO56007.1 - 0.0055 16.0 0.0 0.014 14.6 0.0 1.6 1 0 0 1 1 1 1 Thi4 family COX5A PF02284.16 EGO56007.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Mqo PF06039.15 EGO56007.1 - 0.15 10.6 0.6 3.8 5.9 0.1 2.4 3 0 0 3 3 3 0 Malate:quinone oxidoreductase (Mqo) Creatininase PF02633.14 EGO56007.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Creatinine amidohydrolase MFS_1 PF07690.16 EGO56008.1 - 1.2e-09 37.6 26.7 1.2e-09 37.6 26.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily ADH_N PF08240.12 EGO56009.1 - 0.0038 17.1 0.0 0.009 15.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO56009.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Bac_luciferase PF00296.20 EGO56010.1 - 9.9e-54 182.9 1.9 1.3e-53 182.5 1.9 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase eIF3_N PF09440.10 EGO56011.1 - 9.8e-52 174.9 3.2 7e-50 168.9 5.1 2.5 2 1 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EGO56011.1 - 4.4e-16 59.3 0.2 4.4e-16 59.3 0.2 2.1 3 0 0 3 3 3 1 PCI domain RPN7 PF10602.9 EGO56011.1 - 0.0082 15.9 0.4 0.024 14.3 0.2 1.7 1 1 1 2 2 2 1 26S proteasome subunit RPN7 Caprin-1_dimer PF18293.1 EGO56011.1 - 0.027 15.0 0.7 0.083 13.4 0.2 2.1 2 0 0 2 2 2 0 Caprin-1 dimerization domain CSN8_PSD8_EIF3K PF10075.9 EGO56011.1 - 0.036 14.0 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family HrcA PF01628.21 EGO56011.1 - 0.14 12.1 1.5 3.9 7.3 0.0 2.8 3 0 0 3 3 3 0 HrcA protein C terminal domain TPR_19 PF14559.6 EGO56011.1 - 0.23 12.0 1.7 4.1 8.0 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Img2 PF05046.14 EGO56012.1 - 1.4e-24 86.1 0.0 2e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.22 EGO56012.1 - 0.084 13.4 0.5 0.57 10.7 0.5 2.1 1 1 0 1 1 1 0 Translation initiation factor SUI1 Dicty_REP PF05086.12 EGO56012.1 - 0.32 8.9 0.8 0.33 8.9 0.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ARID PF01388.21 EGO56013.1 - 5.1e-18 65.5 0.0 1.8e-17 63.8 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 EGO56013.1 - 0.047 13.0 0.2 0.083 12.2 0.2 1.4 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa EVE PF01878.18 EGO56014.1 - 9.2e-46 155.5 0.0 1.6e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 EVE domain Velvet PF11754.8 EGO56014.1 - 0.096 12.6 2.3 0.14 12.1 2.3 1.2 1 0 0 1 1 1 0 Velvet factor DUF4551 PF15087.6 EGO56014.1 - 2 7.1 9.1 2.6 6.8 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) U3_assoc_6 PF08640.11 EGO56015.1 - 7.3e-25 86.9 0.3 3.5e-24 84.7 0.2 2.2 2 1 1 3 3 3 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 EGO56015.1 - 0.0013 17.9 0.0 0.011 14.8 0.0 2.1 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EGO56015.1 - 0.022 15.6 3.1 7.8 7.6 0.0 4.4 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGO56015.1 - 0.064 13.9 0.0 0.27 11.9 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Frag1 PF10277.9 EGO56016.1 - 6.3e-40 137.0 10.9 6.3e-40 137.0 10.9 3.2 3 1 1 4 4 4 2 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 EGO56016.1 - 0.044 13.3 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.16 EGO56017.1 - 6.2e-21 74.7 24.1 6.2e-21 74.7 24.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO56017.1 - 6.6e-05 21.9 6.5 6.6e-05 21.9 6.5 2.9 1 1 2 3 3 3 1 Sugar (and other) transporter Band_7 PF01145.25 EGO56018.1 - 2.3e-15 57.0 0.0 2.3e-15 57.0 0.0 3.2 2 1 0 2 2 2 1 SPFH domain / Band 7 family ANAPC1 PF12859.7 EGO56020.1 - 1.9e-38 132.0 0.2 4.6e-38 130.7 0.2 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EGO56020.1 - 4.4e-06 26.9 1.4 0.022 15.2 0.0 4.2 4 0 0 4 4 4 2 Proteasome/cyclosome repeat Clathrin PF00637.20 EGO56021.1 - 3.6e-20 72.3 0.4 8.5e-19 67.9 0.1 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS SDA1 PF05285.12 EGO56021.1 - 0.0012 18.3 1.8 0.0026 17.3 1.8 1.5 1 0 0 1 1 1 1 SDA1 Vps39_1 PF10366.9 EGO56021.1 - 0.0028 17.9 0.1 0.011 16.0 0.0 2.0 2 0 0 2 2 1 1 Vacuolar sorting protein 39 domain 1 RXT2_N PF08595.11 EGO56021.1 - 0.0043 17.1 5.0 0.013 15.5 5.0 1.8 1 0 0 1 1 1 1 RXT2-like, N-terminal YL1 PF05764.13 EGO56021.1 - 0.0055 16.8 1.5 0.011 15.8 1.5 1.5 1 0 0 1 1 1 1 YL1 nuclear protein BUD22 PF09073.10 EGO56021.1 - 0.024 14.0 1.8 0.054 12.8 1.8 1.6 1 0 0 1 1 1 0 BUD22 zf-RING_11 PF17123.5 EGO56021.1 - 0.034 13.9 1.4 0.07 12.9 1.4 1.6 1 0 0 1 1 1 0 RING-like zinc finger Nic96 PF04097.14 EGO56021.1 - 0.042 12.3 0.7 3.1 6.1 0.0 2.1 1 1 1 2 2 2 0 Nup93/Nic96 TPR_7 PF13176.6 EGO56021.1 - 0.047 13.7 0.2 0.75 10.0 0.1 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat WD40 PF00400.32 EGO56021.1 - 0.05 14.5 0.7 17 6.4 0.0 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat zf-RING_5 PF14634.6 EGO56021.1 - 0.057 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EGO56021.1 - 0.16 12.3 0.2 0.34 11.3 0.2 1.6 1 0 0 1 1 1 0 Ring finger domain NOA36 PF06524.12 EGO56021.1 - 0.18 11.1 14.8 0.41 9.9 14.8 1.5 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 EGO56021.1 - 0.29 10.8 11.7 0.98 9.1 11.7 1.9 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EGO56021.1 - 0.56 8.3 10.8 0.92 7.6 10.8 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 EGO56021.1 - 4 7.3 12.1 11 5.9 12.1 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Pectate_lyase_3 PF12708.7 EGO56022.1 - 1.6e-79 266.7 17.5 1.5e-68 230.9 7.0 3.1 2 1 1 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EGO56022.1 - 1.7e-05 24.4 1.4 0.029 14.1 0.4 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DNase_NucA_NucB PF14040.6 EGO56022.1 - 0.0001 22.7 5.5 0.00012 22.4 0.1 2.9 3 0 0 3 3 3 1 Deoxyribonuclease NucA/NucB LysM PF01476.20 EGO56023.1 - 0.0029 17.6 0.0 0.0094 16.0 0.0 1.8 2 0 0 2 2 2 1 LysM domain SET PF00856.28 EGO56025.1 - 3.3e-15 56.9 0.2 2.7e-14 53.9 0.2 2.2 1 1 0 1 1 1 1 SET domain SAF PF08666.12 EGO56025.1 - 0.011 16.3 0.1 6 7.6 0.0 2.4 2 0 0 2 2 2 0 SAF domain Glyco_trans_2_3 PF13632.6 EGO56026.1 - 0.021 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family group 2 DOCK_N PF16172.5 EGO56027.1 - 2.1e-126 421.9 0.0 3.6e-126 421.1 0.0 1.4 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 EGO56027.1 - 1.2e-35 123.1 0.0 2.3e-35 122.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 EGO56027.1 - 2.8e-29 102.2 0.2 1.6e-28 99.7 0.2 1.9 1 1 0 1 1 1 1 Dock homology region 2 SH3_1 PF00018.28 EGO56027.1 - 1.5e-05 24.5 0.0 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGO56027.1 - 0.0011 18.7 0.0 0.0044 16.9 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain DUF3824 PF12868.7 EGO56027.1 - 6.9 7.3 13.8 1.8 9.2 4.0 2.9 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Esterase_phd PF10503.9 EGO56030.1 - 3e-23 82.5 1.6 4.3e-23 82.0 1.6 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EGO56030.1 - 2e-12 47.0 0.4 3.5e-12 46.2 0.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGO56030.1 - 0.00054 19.9 0.1 0.00084 19.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EGO56030.1 - 0.0016 18.2 0.4 0.0055 16.4 0.2 1.8 2 0 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.16 EGO56030.1 - 0.0052 16.6 0.1 0.86 9.4 0.1 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase COesterase PF00135.28 EGO56030.1 - 0.015 14.2 0.1 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 Carboxylesterase family Tannase PF07519.11 EGO56030.1 - 0.019 13.9 0.5 0.029 13.3 0.5 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 EGO56030.1 - 0.072 12.4 0.2 0.34 10.2 0.2 1.9 1 1 0 2 2 2 0 Serine aminopeptidase, S33 AXE1 PF05448.12 EGO56030.1 - 0.083 11.5 0.1 0.28 9.8 0.1 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 EGO56030.1 - 0.42 10.2 3.0 0.82 9.3 2.8 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ank_4 PF13637.6 EGO56031.1 - 1.6e-06 28.5 0.0 0.037 14.6 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO56031.1 - 9.1e-06 26.2 0.0 0.00014 22.4 0.0 2.7 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGO56031.1 - 5.5e-05 23.4 0.1 0.2 12.2 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGO56031.1 - 0.00011 22.4 0.2 0.038 14.3 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO56031.1 - 0.00041 20.6 0.0 0.027 15.0 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat DNA_binding_1 PF01035.20 EGO56033.1 - 1.9e-25 88.8 0.1 2.4e-25 88.5 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain His_Phos_1 PF00300.22 EGO56034.1 - 6.2e-28 97.8 0.6 8.4e-28 97.4 0.6 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 EGO56034.1 - 0.083 12.2 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) SDA1 PF05285.12 EGO56035.1 - 2.3e-85 287.1 55.7 1.4e-84 284.5 43.5 3.0 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 EGO56035.1 - 1.5e-18 66.8 0.1 4.4e-18 65.3 0.1 1.9 1 0 0 1 1 1 1 NUC130/3NT domain EABR PF12180.8 EGO56035.1 - 0.012 15.2 0.7 0.028 14.0 0.7 1.6 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 YL1 PF05764.13 EGO56035.1 - 1.3 9.0 39.6 0.36 10.9 2.8 2.6 2 1 0 2 2 2 0 YL1 nuclear protein HlyD PF00529.20 EGO56036.1 - 0.17 11.8 3.0 2.9 7.9 0.4 2.6 3 0 0 3 3 3 0 HlyD membrane-fusion protein of T1SS Cadherin-like PF12733.7 EGO56036.1 - 0.34 11.5 6.2 12 6.5 6.7 2.7 2 0 0 2 2 2 0 Cadherin-like beta sandwich domain Alpha-amylase PF00128.24 EGO56037.1 - 2.6e-17 63.4 0.0 1.3e-16 61.1 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 EGO56037.1 - 9e-06 24.2 0.1 0.0053 15.0 0.0 2.9 2 1 1 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 EGO56037.1 - 0.01 15.9 3.3 0.015 15.5 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) HSP70 PF00012.20 EGO56038.1 - 6.4e-61 206.3 15.5 1.3e-55 188.8 0.0 3.1 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 EGO56038.1 - 0.00054 18.9 0.1 0.0021 16.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DUF948 PF06103.11 EGO56038.1 - 0.038 14.2 2.6 0.1 12.8 0.1 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 EGO56038.1 - 0.082 13.5 4.8 3.3 8.3 1.3 3.9 2 2 1 3 3 3 0 Syntaxin 6, N-terminal DUF3484 PF11983.8 EGO56038.1 - 0.87 10.7 0.0 0.87 10.7 0.0 3.1 3 0 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch Chorion_2 PF03964.15 EGO56038.1 - 0.91 10.4 5.6 3.5 8.5 0.0 3.0 2 0 0 2 2 2 0 Chorion family 2 SpoVT_C PF15714.5 EGO56038.1 - 2.4 8.2 8.8 5.8 7.0 0.0 3.9 4 0 0 4 4 4 0 Stage V sporulation protein T C-terminal, transcription factor Asp PF00026.23 EGO56039.1 - 6e-36 124.4 0.1 1.5e-24 87.1 0.1 3.2 3 0 0 3 3 3 3 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO56039.1 - 5.1e-09 36.6 0.0 0.00013 22.2 0.0 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal BBP1_C PF15272.6 EGO56040.1 - 0.00068 19.5 3.5 0.001 18.9 3.5 1.2 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal DUF4140 PF13600.6 EGO56040.1 - 0.00098 19.5 1.5 0.0019 18.6 1.5 1.4 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) Filament PF00038.21 EGO56040.1 - 0.011 15.4 2.7 0.011 15.3 2.7 1.1 1 0 0 1 1 1 0 Intermediate filament protein Fez1 PF06818.15 EGO56040.1 - 0.012 16.1 1.6 0.017 15.6 1.6 1.2 1 0 0 1 1 1 0 Fez1 KxDL PF10241.9 EGO56040.1 - 0.02 15.2 1.1 0.043 14.1 0.4 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein V_ATPase_I PF01496.19 EGO56040.1 - 0.02 12.8 0.4 0.025 12.5 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Csm1_N PF18504.1 EGO56040.1 - 0.058 13.7 2.1 0.093 13.1 0.7 2.0 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF4164 PF13747.6 EGO56040.1 - 0.061 13.6 4.8 0.11 12.8 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DivIC PF04977.15 EGO56040.1 - 0.062 13.1 2.3 0.65 9.8 1.0 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF1993 PF09351.10 EGO56040.1 - 0.12 12.5 1.4 0.16 12.1 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) BLOC1_2 PF10046.9 EGO56040.1 - 0.12 12.7 2.4 2.3 8.6 0.4 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EMP24_GP25L PF01105.24 EGO56040.1 - 0.16 11.9 0.3 0.16 11.9 0.3 1.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF1664 PF07889.12 EGO56040.1 - 0.19 11.7 2.1 0.35 10.9 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 EGO56040.1 - 0.35 11.2 5.6 0.86 9.9 4.0 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF4407 PF14362.6 EGO56040.1 - 0.91 8.8 5.2 1 8.6 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CRT10 PF08728.10 EGO56040.1 - 0.91 7.6 3.7 1.1 7.4 3.7 1.0 1 0 0 1 1 1 0 CRT10 SlyX PF04102.12 EGO56040.1 - 3.4 8.4 6.2 3.1 8.5 1.0 2.8 1 1 2 3 3 3 0 SlyX Bromodomain PF00439.25 EGO56041.1 - 4.6e-08 33.0 0.0 2e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Bromodomain Filament PF00038.21 EGO56042.1 - 0.051 13.1 28.6 0.1 12.1 28.6 1.4 1 0 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.11 EGO56042.1 - 0.2 10.5 27.8 0.88 8.4 27.1 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein TSC22 PF01166.18 EGO56042.1 - 4.9 7.5 8.1 17 5.8 0.3 3.1 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF3037 PF11236.8 EGO56042.1 - 9.9 6.6 10.9 3 8.3 4.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) Cyt-b5 PF00173.28 EGO56043.1 - 6.6e-11 42.2 0.0 1.1e-10 41.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GIIM PF08388.11 EGO56043.1 - 0.041 13.9 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Group II intron, maturase-specific domain Cupredoxin_1 PF13473.6 EGO56044.1 - 0.035 14.2 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 Cupredoxin-like domain Copper-bind PF00127.20 EGO56044.1 - 0.058 13.8 0.4 0.13 12.7 0.4 1.5 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family SSP160 PF06933.11 EGO56044.1 - 1.7 6.7 29.4 0.15 10.2 23.8 1.8 1 1 1 2 2 2 0 Special lobe-specific silk protein SSP160 AF-4 PF05110.13 EGO56044.1 - 8.6 4.3 10.9 11 3.9 10.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CENP-X PF09415.10 EGO56045.1 - 4e-27 94.3 0.0 4e-27 94.3 0.0 2.1 2 1 0 2 2 2 1 CENP-S associating Centromere protein X Pes-10 PF07149.11 EGO56045.1 - 0.47 9.5 13.5 0.62 9.1 13.5 1.2 1 0 0 1 1 1 0 Pes-10 RR_TM4-6 PF06459.12 EGO56045.1 - 1.5 8.6 8.5 1.8 8.4 8.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.8 EGO56045.1 - 3.9 6.5 14.9 5.5 6.0 14.9 1.1 1 0 0 1 1 1 0 SprA-related family PPP4R2 PF09184.11 EGO56045.1 - 4.1 6.9 21.4 5.6 6.5 21.4 1.2 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 EGO56045.1 - 5.3 5.7 9.3 5.8 5.6 9.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mito_carr PF00153.27 EGO56046.1 - 3.9e-68 225.4 3.4 8e-25 86.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 EGO56046.1 - 0.093 12.5 0.7 0.3 10.9 0.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Ribosomal_S25 PF03297.15 EGO56047.1 - 9.6e-39 131.7 5.3 1e-38 131.6 5.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein RNA_pol_Rpc34 PF05158.12 EGO56047.1 - 0.0016 17.9 0.3 0.0027 17.1 0.1 1.4 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_24 PF13412.6 EGO56047.1 - 0.003 17.1 0.1 0.0049 16.4 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.12 EGO56047.1 - 0.0051 16.5 0.1 0.0068 16.1 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR_2 PF12802.7 EGO56047.1 - 0.013 15.4 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 EGO56047.1 - 0.019 15.3 0.0 0.029 14.7 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_IclR PF09339.10 EGO56047.1 - 0.063 13.1 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_11 PF08279.12 EGO56047.1 - 0.071 13.1 0.0 0.096 12.7 0.0 1.2 1 0 0 1 1 1 0 HTH domain TrmB PF01978.19 EGO56047.1 - 0.073 13.0 0.2 0.097 12.6 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Ribosomal_S7 PF00177.21 EGO56048.1 - 1.2e-37 128.9 1.6 1.5e-37 128.6 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Acetyltransf_10 PF13673.7 EGO56049.1 - 1.6e-06 28.1 0.0 0.013 15.4 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 EGO56049.1 - 1e-05 26.2 0.1 0.032 14.9 0.0 3.0 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO56049.1 - 1.3e-05 25.4 0.0 3.6e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EGO56049.1 - 0.00015 21.9 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 EGO56049.1 - 0.00015 22.1 0.0 0.00037 20.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGO56049.1 - 0.035 14.2 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short_C2 PF13561.6 EGO56050.1 - 3.1e-44 151.3 0.0 1.5e-42 145.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO56050.1 - 1.9e-43 148.2 0.0 2.6e-42 144.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO56050.1 - 9.3e-08 32.2 0.0 2.2e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO56050.1 - 0.0016 17.9 0.0 0.0025 17.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGO56050.1 - 0.007 15.5 0.0 0.016 14.4 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGO56050.1 - 0.017 15.0 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 EGO56050.1 - 0.04 13.3 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Baculo_PEP_C PF04513.12 EGO56051.1 - 2.2 8.3 18.9 0.031 14.3 2.1 4.5 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tubulin PF00091.25 EGO56055.1 - 1.5e-66 224.4 0.0 2.2e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGO56055.1 - 3.6e-50 169.4 0.1 5.9e-50 168.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGO56055.1 - 0.0011 18.7 0.0 0.003 17.3 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain MAD PF05557.13 EGO56056.1 - 6.8e-08 31.4 17.0 1e-07 30.8 17.0 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein Lebercilin PF15619.6 EGO56056.1 - 0.00018 21.3 24.0 0.00039 20.1 24.0 1.5 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 EGO56056.1 - 0.0028 16.6 16.7 0.006 15.5 16.7 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein BLOC1_2 PF10046.9 EGO56056.1 - 0.0029 17.9 17.1 0.04 14.2 4.4 2.8 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 EGO56056.1 - 0.0053 14.8 6.4 0.0089 14.0 6.4 1.3 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 EGO56056.1 - 0.029 14.5 20.0 0.068 13.3 20.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-C4H2 PF10146.9 EGO56056.1 - 0.037 14.3 6.8 0.096 13.0 6.8 1.8 1 0 0 1 1 1 0 Zinc finger-containing protein Exonuc_VII_L PF02601.15 EGO56056.1 - 0.044 13.4 11.0 0.06 12.9 10.1 1.6 2 0 0 2 2 1 0 Exonuclease VII, large subunit HAUS5 PF14817.6 EGO56056.1 - 0.07 11.9 10.4 0.12 11.1 10.4 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 GIDA_assoc PF13932.6 EGO56056.1 - 0.097 12.8 6.5 0.2 11.8 6.5 1.6 1 0 0 1 1 1 0 GidA associated domain HMMR_N PF15905.5 EGO56056.1 - 0.14 11.6 19.7 0.27 10.7 19.7 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Cob_adeno_trans PF01923.18 EGO56056.1 - 0.23 11.6 6.9 0.59 10.2 5.3 2.4 1 1 1 2 2 2 0 Cobalamin adenosyltransferase GIT_CC PF16559.5 EGO56056.1 - 0.24 11.3 4.3 0.69 9.8 4.3 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3450 PF11932.8 EGO56056.1 - 0.65 9.2 12.4 0.19 11.0 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Prominin PF05478.11 EGO56056.1 - 0.67 7.8 5.3 1.1 7.2 5.3 1.3 1 0 0 1 1 1 0 Prominin GIT1_C PF12205.8 EGO56056.1 - 0.76 9.9 5.8 2.5 8.3 2.1 2.6 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term GAS PF13851.6 EGO56056.1 - 0.82 9.0 24.7 0.74 9.1 13.4 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding THOC7 PF05615.13 EGO56056.1 - 1 9.6 20.8 4 7.7 3.1 3.2 2 1 1 3 3 3 0 Tho complex subunit 7 DUF4407 PF14362.6 EGO56056.1 - 1.1 8.5 12.7 2.4 7.4 12.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OEP PF02321.18 EGO56056.1 - 1.8 8.3 7.3 1.5 8.6 5.4 1.7 1 1 1 2 2 2 0 Outer membrane efflux protein DUF1664 PF07889.12 EGO56056.1 - 2.2 8.3 14.2 0.49 10.4 6.7 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) Macoilin PF09726.9 EGO56056.1 - 2.2 6.7 14.0 3.9 5.9 14.0 1.3 1 0 0 1 1 1 0 Macoilin family Fzo_mitofusin PF04799.13 EGO56056.1 - 2.3 7.8 11.8 0.89 9.1 4.6 2.5 1 1 0 2 2 2 0 fzo-like conserved region PHM7_cyt PF14703.6 EGO56056.1 - 2.3 8.4 12.0 3.2 8.0 9.5 2.3 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter CENP-F_leu_zip PF10473.9 EGO56056.1 - 3.1 7.8 26.4 10 6.1 23.9 2.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OmpH PF03938.14 EGO56056.1 - 3.7 7.9 21.1 3.4 8.0 5.8 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF745 PF05335.13 EGO56056.1 - 3.9 7.2 13.4 1.7 8.4 7.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF2203 PF09969.9 EGO56056.1 - 4 8.2 13.9 16 6.3 4.8 3.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Fez1 PF06818.15 EGO56056.1 - 4.7 7.6 21.0 4.1 7.8 18.9 2.0 2 1 0 2 2 1 0 Fez1 NPV_P10 PF05531.12 EGO56056.1 - 5.7 7.5 9.5 67 4.0 6.0 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CEP63 PF17045.5 EGO56056.1 - 6.3 6.6 24.0 2.5 8.0 10.2 2.9 2 1 0 2 2 2 0 Centrosomal protein of 63 kDa SHE3 PF17078.5 EGO56056.1 - 6.4 6.4 22.3 8.1 6.1 20.1 2.2 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 HR1 PF02185.16 EGO56056.1 - 8.2 6.6 15.8 0.86 9.8 6.6 3.4 2 1 0 2 2 2 0 Hr1 repeat BTB_2 PF02214.22 EGO56058.1 - 2.7e-05 24.4 0.1 0.078 13.3 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain zf-CSL PF05207.13 EGO56059.1 - 1.6e-22 78.9 0.3 2e-22 78.7 0.3 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn_ribbon_SprT PF17283.2 EGO56059.1 - 0.095 12.6 0.1 14 5.7 0.0 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Prok-RING_1 PF14446.6 EGO56059.1 - 0.15 12.0 2.5 0.28 11.1 2.5 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 tRNA-synt_1 PF00133.22 EGO56061.1 - 3.8e-39 134.4 0.1 1.3e-28 99.6 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EGO56061.1 - 2.2e-17 62.9 0.1 8.6e-11 41.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGO56061.1 - 1.8e-13 50.7 0.6 3.8e-13 49.7 0.3 1.8 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGO56061.1 - 4.1e-09 36.2 0.0 9.2e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF3574 PF12098.8 EGO56061.1 - 0.04 13.7 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) tRNA-synt_1f PF01921.18 EGO56061.1 - 0.086 11.7 0.0 0.4 9.5 0.0 2.1 3 0 0 3 3 3 0 tRNA synthetases class I (K) Ice_nucleation PF00818.17 EGO56062.1 - 1.1 9.5 4.2 2.7 8.2 4.2 1.5 1 0 0 1 1 1 0 Ice nucleation protein repeat Clat_adaptor_s PF01217.20 EGO56063.1 - 7.6e-43 145.8 0.0 1.4e-42 145.0 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.16 EGO56064.1 - 5.8e-38 129.3 0.1 7.3e-38 129.0 0.1 1.1 1 0 0 1 1 1 1 Frataxin-like domain Tma16 PF11176.8 EGO56064.1 - 0.12 12.2 0.1 0.2 11.6 0.1 1.2 1 0 0 1 1 1 0 Translation machinery-associated protein 16 Tetraspanin PF00335.20 EGO56065.1 - 0.00024 20.9 0.0 0.00055 19.7 0.0 1.5 2 0 0 2 2 2 1 Tetraspanin family DEAD PF00270.29 EGO56066.1 - 1.4e-33 116.1 0.0 2.5e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO56066.1 - 1.4e-21 76.9 0.0 3e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO56066.1 - 2.8e-05 24.2 0.7 0.0001 22.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 EGO56066.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain CDC45 PF02724.14 EGO56066.1 - 0.3 9.3 17.6 0.43 8.8 17.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.10 EGO56066.1 - 4.3 5.9 7.9 6.3 5.4 7.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Menin PF05053.13 EGO56066.1 - 8.4 4.6 12.5 14 3.9 12.5 1.2 1 0 0 1 1 1 0 Menin PIGA PF08288.12 EGO56067.1 - 8.6e-47 157.7 1.5 8.6e-47 157.7 1.5 2.6 3 0 0 3 3 3 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EGO56067.1 - 8e-30 104.1 1.0 1.5e-29 103.1 1.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EGO56067.1 - 2.1e-26 92.5 0.0 3.2e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGO56067.1 - 2.5e-23 83.0 0.1 4.6e-23 82.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGO56067.1 - 1.4e-14 54.8 0.0 2.5e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EGO56067.1 - 5.8e-06 26.4 0.1 1.1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EGO56067.1 - 1.3e-05 25.5 0.0 8.4e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 RasGEF PF00617.19 EGO56068.1 - 7e-48 163.2 0.0 1.5e-47 162.1 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGO56068.1 - 2.9e-15 56.4 0.0 1e-14 54.6 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 EGO56068.1 - 0.00014 21.7 0.0 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGO56068.1 - 0.0029 17.2 0.0 0.0057 16.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_16 PF18348.1 EGO56068.1 - 0.18 11.6 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Jacalin PF01419.17 EGO56069.1 - 1.1e-05 25.4 0.4 4.4e-05 23.4 0.3 1.9 2 0 0 2 2 2 1 Jacalin-like lectin domain Ank_2 PF12796.7 EGO56070.1 - 2.5e-28 98.5 0.0 9.9e-08 32.5 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO56070.1 - 2.7e-21 73.4 1.6 0.017 15.6 0.0 7.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 EGO56070.1 - 6.2e-20 71.3 1.7 1.3e-05 25.7 0.0 6.1 3 1 4 7 7 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EGO56070.1 - 1.2e-13 50.8 6.5 0.34 11.4 0.0 7.2 6 0 0 6 6 6 3 Ankyrin repeat NACHT PF05729.12 EGO56070.1 - 1.2e-10 41.6 0.1 3.3e-10 40.1 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGO56070.1 - 6.1e-09 36.5 0.3 3e-08 34.2 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGO56070.1 - 1.5e-06 28.6 0.5 5e-06 26.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain Ank_5 PF13857.6 EGO56070.1 - 7.9e-06 26.0 0.3 1.5 9.3 0.0 5.6 2 1 4 6 6 6 2 Ankyrin repeats (many copies) ATPase_2 PF01637.18 EGO56070.1 - 0.019 14.9 0.0 0.086 12.7 0.0 2.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Ploopntkinase3 PF18751.1 EGO56070.1 - 0.028 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 EGO56070.1 - 0.036 14.5 0.0 0.098 13.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 EGO56070.1 - 0.045 13.0 0.1 1.9 7.6 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) DUF4795 PF16043.5 EGO56070.1 - 0.14 11.8 4.3 0.68 9.5 0.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) AAA_30 PF13604.6 EGO56070.1 - 0.17 11.6 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.23 EGO56071.1 - 1.9e-62 211.0 0.2 3.4e-62 210.2 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO56071.1 - 2.5e-12 47.1 0.9 1.2e-11 44.9 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO56071.1 - 2.1e-08 34.3 0.0 1.5e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGO56071.1 - 2.6e-08 33.8 0.0 7e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EGO56071.1 - 0.0062 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_34 PF13872.6 EGO56071.1 - 0.01 14.7 0.1 0.04 12.8 0.1 1.9 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 SWI2_SNF2 PF18766.1 EGO56071.1 - 0.012 15.3 0.0 0.32 10.6 0.0 2.3 2 0 0 2 2 2 0 SWI2/SNF2 ATPase NACHT PF05729.12 EGO56071.1 - 0.02 14.8 0.4 1.2 9.0 0.1 2.8 3 0 0 3 3 3 0 NACHT domain zf-C3HC4 PF00097.25 EGO56071.1 - 0.042 13.7 0.4 0.089 12.7 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO56071.1 - 0.093 12.6 0.3 0.19 11.6 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mid2 PF04478.12 EGO56071.1 - 0.14 12.0 0.2 0.32 10.8 0.2 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Herpes_gE PF02480.16 EGO56074.1 - 0.0066 15.3 0.0 0.0085 14.9 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E RAP1 PF07218.11 EGO56074.1 - 0.082 11.2 0.2 0.12 10.7 0.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Alpha_GJ PF03229.13 EGO56074.1 - 0.088 13.4 7.1 0.041 14.4 3.3 2.2 1 1 1 2 2 2 0 Alphavirus glycoprotein J Epimerase PF01370.21 EGO56075.1 - 1.4e-14 54.2 0.0 2.2e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO56075.1 - 1.8e-09 37.5 0.0 2.6e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGO56075.1 - 7e-06 25.4 0.0 1.3e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EGO56075.1 - 7.7e-06 25.1 0.0 1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGO56075.1 - 5.9e-05 22.4 0.1 0.0017 17.6 0.1 2.6 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EGO56075.1 - 0.0054 16.7 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EGO56075.1 - 0.027 13.9 0.0 0.059 12.8 0.0 1.5 2 0 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EGO56075.1 - 0.05 12.7 0.0 2.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sulfotransfer_4 PF17784.1 EGO56076.1 - 6.8e-40 137.2 0.1 9.4e-40 136.7 0.1 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGO56076.1 - 9.7e-05 22.8 0.1 0.0077 16.6 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase family GH131_N PF18271.1 EGO56077.1 - 2.2e-66 224.2 0.4 3e-66 223.8 0.4 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 EGO56077.1 - 5.2e-11 42.3 7.1 5.2e-11 42.3 7.1 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain zf-RING_5 PF14634.6 EGO56079.1 - 0.012 15.6 2.8 0.02 14.8 2.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain MFS_1 PF07690.16 EGO56080.1 - 1.4e-23 83.4 38.8 1.5e-23 83.3 33.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO56080.1 - 8.3e-10 38.1 28.3 5.7e-09 35.4 28.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter LacAB_rpiB PF02502.18 EGO56080.1 - 0.15 12.0 0.3 0.29 11.1 0.3 1.3 1 0 0 1 1 1 0 Ribose/Galactose Isomerase PUCC PF03209.15 EGO56080.1 - 0.85 8.6 14.2 2.1 7.2 14.1 1.7 1 1 0 1 1 1 0 PUCC protein DUF3302 PF11742.8 EGO56080.1 - 2.6 8.2 0.0 2.6 8.2 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3302) AcetylCoA_hydro PF02550.15 EGO56082.1 - 1.8e-46 158.6 0.0 2.9e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 EGO56082.1 - 1.9e-39 135.0 0.0 3.4e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.23 EGO56082.1 - 0.057 12.8 0.0 0.46 9.8 0.0 2.3 2 0 0 2 2 2 0 Coenzyme A transferase MFS_1 PF07690.16 EGO56083.1 - 1.8e-16 60.0 28.0 1.8e-16 60.0 28.0 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGO56083.1 - 3.5e-12 46.3 6.0 3.5e-12 46.3 6.0 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 EGO56083.1 - 0.00062 18.7 10.3 0.0011 17.9 4.9 2.3 2 0 0 2 2 2 2 MFS_1 like family HET PF06985.11 EGO56084.1 - 1.1e-40 139.3 0.1 2.2e-40 138.3 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1970 PF09301.10 EGO56085.1 - 7.5 6.9 9.1 0.57 10.5 0.7 2.7 2 1 2 4 4 4 0 Domain of unknown function (DUF1970) OPT PF03169.15 EGO56086.1 - 1.3e-177 592.2 50.4 1.5e-177 592.0 50.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.6 EGO56086.1 - 4.8 6.4 10.3 0.65 9.3 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) DUF2207 PF09972.9 EGO56086.1 - 7.7 5.2 11.0 4.8 5.8 7.9 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Peptidase_S9 PF00326.21 EGO56087.1 - 1e-05 25.2 0.6 2.8e-05 23.7 0.6 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EGO56087.1 - 0.055 13.3 0.2 0.12 12.2 0.1 1.5 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase ArabFuran-catal PF09206.11 EGO56088.1 - 1.3e-148 494.5 13.8 1.4e-148 494.4 13.8 1.0 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic GrlR PF16518.5 EGO56088.1 - 0.13 12.2 1.2 0.29 11.1 0.1 2.2 2 1 1 3 3 3 0 T3SS negative regulator,GrlR EcKinase PF02958.20 EGO56089.1 - 4.6e-12 45.9 0.0 5.1e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 EGO56089.1 - 1.5e-06 28.3 0.0 2.6e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGO56089.1 - 2.4e-05 23.4 0.0 3.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Fungal_trans_2 PF11951.8 EGO56090.1 - 4.7e-16 58.6 4.9 7.3e-16 58.0 4.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO56090.1 - 8.7e-07 29.0 13.2 8.7e-07 29.0 13.2 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HypA PF01155.19 EGO56090.1 - 4.1 7.5 7.2 8.9 6.4 4.8 2.5 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA AnmK PF03702.14 EGO56091.1 - 4.3e-84 282.7 0.0 5e-84 282.5 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Sugar_tr PF00083.24 EGO56092.1 - 5.8e-94 315.5 23.9 6.6e-94 315.3 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO56092.1 - 2.6e-27 95.7 42.3 8.5e-16 57.8 17.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_12 PF13087.6 EGO56093.1 - 7.3e-44 149.8 0.1 4e-43 147.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EGO56093.1 - 1e-39 136.0 0.0 9.7e-13 48.7 0.0 5.3 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EGO56093.1 - 6.9e-32 111.3 33.9 2.6e-30 106.1 0.1 6.5 6 0 0 6 6 6 2 AAA domain AAA_30 PF13604.6 EGO56093.1 - 6.9e-22 78.1 0.2 8.9e-06 25.5 0.0 5.8 5 0 0 5 5 5 5 AAA domain AAA_19 PF13245.6 EGO56093.1 - 4.5e-16 59.5 1.8 1.2e-06 28.9 0.0 5.6 4 2 0 4 4 4 2 AAA domain AAA_lid_6 PF17866.1 EGO56093.1 - 8.5e-16 57.9 5.7 8.7e-08 32.2 0.1 3.5 2 0 0 2 2 2 2 AAA lid domain AAA_5 PF07728.14 EGO56093.1 - 9.8e-13 48.3 0.4 0.21 11.6 0.0 5.0 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGO56093.1 - 4.9e-12 46.3 4.2 0.31 11.3 0.0 7.5 5 3 0 5 5 4 4 AAA domain Mg_chelatase PF01078.21 EGO56093.1 - 4.8e-09 35.9 0.1 0.037 13.4 0.0 5.0 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGO56093.1 - 5.2e-09 36.1 1.9 0.27 10.9 0.1 5.0 4 0 0 4 4 4 2 AAA domain RuvB_N PF05496.12 EGO56093.1 - 2.3e-08 33.9 0.1 0.3 10.8 0.0 4.7 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGO56093.1 - 2.6e-08 34.4 12.2 0.14 12.5 0.0 6.1 6 0 0 6 6 4 3 AAA ATPase domain RNA_helicase PF00910.22 EGO56093.1 - 1.6e-07 31.7 0.5 0.8 10.1 0.0 4.7 4 0 0 4 4 4 1 RNA helicase IstB_IS21 PF01695.17 EGO56093.1 - 3.9e-07 30.0 0.0 3.6 7.3 0.0 4.6 4 0 0 4 4 4 1 IstB-like ATP binding protein Torsin PF06309.11 EGO56093.1 - 7.1e-07 29.4 0.1 4 7.6 0.0 4.8 4 1 0 4 4 4 1 Torsin AAA_7 PF12775.7 EGO56093.1 - 7.8e-07 28.8 0.1 2 7.9 0.0 4.5 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_10 PF12846.7 EGO56093.1 - 5.3e-06 25.6 0.1 0.00026 20.0 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain ResIII PF04851.15 EGO56093.1 - 6.5e-06 26.2 0.1 0.015 15.3 0.0 5.0 6 0 0 6 6 5 1 Type III restriction enzyme, res subunit AAA_18 PF13238.6 EGO56093.1 - 1.3e-05 25.8 12.9 3.9 8.0 0.0 6.6 5 1 0 5 5 5 1 AAA domain AAA_14 PF13173.6 EGO56093.1 - 1.5e-05 25.0 0.0 0.057 13.5 0.0 4.0 4 0 0 4 4 3 1 AAA domain Sigma54_activat PF00158.26 EGO56093.1 - 2.1e-05 24.3 1.1 17 5.1 0.0 5.8 7 1 0 7 7 5 0 Sigma-54 interaction domain AAA_33 PF13671.6 EGO56093.1 - 0.0001 22.5 12.4 0.75 10.0 0.1 5.8 5 1 0 5 5 4 2 AAA domain ATPase PF06745.13 EGO56093.1 - 0.00011 21.7 2.3 0.12 11.7 0.0 4.6 4 0 0 4 4 4 1 KaiC TniB PF05621.11 EGO56093.1 - 0.00017 21.0 0.0 14 5.0 0.0 5.6 5 1 1 6 6 6 0 Bacterial TniB protein PhoH PF02562.16 EGO56093.1 - 0.00029 20.3 0.3 3.2 7.2 0.0 4.5 4 0 0 4 4 4 1 PhoH-like protein KTI12 PF08433.10 EGO56093.1 - 0.0018 17.8 0.4 9 5.7 0.0 4.9 5 0 0 5 5 4 0 Chromatin associated protein KTI12 Helicase_RecD PF05127.14 EGO56093.1 - 0.0033 17.3 0.3 1.1 9.1 0.0 3.4 2 0 0 2 2 2 1 Helicase SRP54 PF00448.22 EGO56093.1 - 0.0066 16.1 2.1 0.82 9.3 0.1 4.1 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain DUF2075 PF09848.9 EGO56093.1 - 0.016 14.5 0.0 0.016 14.5 0.0 6.9 8 1 1 9 9 7 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EGO56093.1 - 0.028 14.3 4.6 23 4.8 0.0 4.5 4 0 0 4 4 4 0 NTPase Rad17 PF03215.15 EGO56093.1 - 0.061 13.2 0.0 14 5.6 0.0 3.4 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_28 PF13521.6 EGO56093.1 - 0.079 13.2 11.7 3.1 8.0 0.1 5.5 6 0 0 6 6 4 0 AAA domain AAA_25 PF13481.6 EGO56093.1 - 0.41 10.2 7.5 5.8 6.4 0.0 4.8 5 0 0 5 5 4 0 AAA domain ABC_tran PF00005.27 EGO56093.1 - 0.82 10.2 7.3 79 3.8 0.1 5.4 5 0 0 5 5 5 0 ABC transporter CbiA PF01656.23 EGO56093.1 - 1 9.4 3.6 15 5.6 0.0 3.8 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain HET PF06985.11 EGO56095.1 - 3.9e-25 88.9 0.0 8.3e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TraT PF05818.12 EGO56096.1 - 0.061 13.0 0.9 0.096 12.4 0.9 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein adh_short PF00106.25 EGO56098.1 - 1.9e-37 128.6 0.0 2.8e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO56098.1 - 1.5e-22 80.3 0.0 2.3e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HET PF06985.11 EGO56098.1 - 5.9e-21 75.4 0.4 1e-19 71.3 0.1 2.4 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Secretin_N_2 PF07655.13 EGO56098.1 - 0.0021 18.6 2.7 0.0021 18.6 2.7 2.8 3 0 0 3 3 3 1 Secretin N-terminal domain DUF1776 PF08643.10 EGO56098.1 - 0.1 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) KH_1 PF00013.29 EGO56100.1 - 2.4e-50 168.2 13.5 4.3e-17 61.7 2.0 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EGO56100.1 - 1.4e-11 44.1 3.7 0.016 15.0 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EGO56100.1 - 1.9e-09 37.3 5.2 0.036 13.9 0.1 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 EGO56100.1 - 1.2e-05 25.2 0.0 0.058 13.4 0.0 3.1 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 EGO56100.1 - 0.017 15.2 2.6 15 5.7 0.1 3.3 3 0 0 3 3 3 0 NusA-like KH domain Asp PF00026.23 EGO56101.1 - 6.5e-37 127.6 0.0 1e-36 127.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EGO56101.1 - 1.6e-05 25.5 0.0 1.6 9.4 0.0 3.8 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EGO56101.1 - 0.00054 20.5 0.0 8.4 7.0 0.0 3.9 3 1 1 4 4 4 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EGO56101.1 - 0.0098 15.7 0.1 0.048 13.4 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal DEAD PF00270.29 EGO56102.1 - 8e-47 159.3 0.1 2.6e-46 157.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO56102.1 - 1.2e-24 86.7 0.1 1.6e-23 83.2 0.0 2.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGO56102.1 - 3.4e-19 68.8 0.7 7.5e-19 67.7 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 EGO56102.1 - 0.00099 18.4 0.0 0.00099 18.4 0.0 2.3 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase DUF4746 PF15928.5 EGO56102.1 - 3.8 6.8 11.7 5.7 6.3 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1754 PF08555.10 EGO56102.1 - 6.7 7.6 23.9 21 6.0 23.9 1.8 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) 6PF2K PF01591.18 EGO56103.1 - 2.9e-79 265.5 0.1 4.1e-79 265.0 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGO56103.1 - 2.1e-36 125.5 0.0 3.2e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGO56103.1 - 1.8e-06 28.2 0.0 3.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EGO56103.1 - 0.0015 18.1 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 NMT1 PF09084.11 EGO56105.1 - 2.6e-78 262.9 0.0 3.1e-78 262.6 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EGO56105.1 - 5.1e-08 32.9 0.1 0.36 10.5 0.0 4.0 3 1 1 4 4 4 3 NMT1-like family Phosphonate-bd PF12974.7 EGO56105.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein FMN_red PF03358.15 EGO56105.1 - 0.091 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 NADPH-dependent FMN reductase DUF829 PF05705.14 EGO56107.1 - 9.3e-33 114.1 0.0 2e-32 113.0 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF5331 PF17265.2 EGO56107.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5331) DUF3176 PF11374.8 EGO56108.1 - 2.9e-18 66.1 4.8 6.7e-18 64.8 4.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) zf-NPL4 PF05020.15 EGO56108.1 - 0.088 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 NPL4 family, putative zinc binding region DUF3176 PF11374.8 EGO56110.1 - 9.2e-17 61.2 1.6 9.2e-17 61.2 1.6 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3176) EI24 PF07264.11 EGO56112.1 - 0.0047 17.2 0.8 0.0047 17.2 0.8 3.1 3 0 0 3 3 3 1 Etoposide-induced protein 2.4 (EI24) DUF3139 PF11337.8 EGO56112.1 - 2.9 8.6 0.0 2.9 8.6 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3139) DUF948 PF06103.11 EGO56112.1 - 5.9 7.2 8.8 1.4 9.2 0.1 4.1 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Phage_holin_6_1 PF09682.10 EGO56112.1 - 7.8 7.0 8.0 15 6.1 0.0 4.1 4 0 0 4 4 4 0 Bacteriophage holin of superfamily 6 (Holin_LLH) PRKCSH PF07915.13 EGO56116.1 - 1.4e-18 67.6 0.2 1.4e-18 67.6 0.2 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EGO56116.1 - 0.04 13.6 0.0 7.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Fungal_trans PF04082.18 EGO56117.1 - 5.3e-08 32.2 0.2 8.1e-08 31.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO56117.1 - 4.7e-07 29.8 12.1 7.4e-07 29.2 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 EGO56117.1 - 0.1 12.9 4.5 0.19 12.1 4.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Mito_fiss_reg PF05308.11 EGO56118.1 - 1.1 9.3 4.7 1.4 9.0 4.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CFEM PF05730.11 EGO56119.1 - 1.5e-07 31.4 6.4 1.5e-07 31.4 6.4 1.6 2 0 0 2 2 2 1 CFEM domain CFEM PF05730.11 EGO56120.1 - 9.1e-14 51.3 10.5 1.1e-13 51.1 10.5 1.1 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.20 EGO56120.1 - 0.019 15.2 0.6 0.035 14.4 0.6 1.4 1 0 0 1 1 1 0 Gamma-thionin family ABC_membrane PF00664.23 EGO56121.1 - 3.9e-88 295.7 30.3 6.1e-47 160.5 5.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGO56121.1 - 1.1e-68 230.0 0.0 1.1e-34 119.9 0.0 2.5 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGO56121.1 - 2.4e-15 56.6 3.6 0.00011 21.7 0.4 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGO56121.1 - 4.6e-08 33.4 0.5 0.048 13.9 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGO56121.1 - 1.3e-07 31.2 0.7 0.0074 16.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGO56121.1 - 4.1e-07 30.5 4.1 0.0048 17.3 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 EGO56121.1 - 1.8e-06 27.1 0.1 0.0031 16.4 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 EGO56121.1 - 6.8e-06 26.1 4.0 0.48 10.2 0.1 4.1 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGO56121.1 - 1.6e-05 24.9 0.1 0.015 15.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 EGO56121.1 - 0.00014 21.2 0.3 0.86 8.9 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_33 PF13671.6 EGO56121.1 - 0.00021 21.4 0.1 1.3 9.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EGO56121.1 - 0.00022 21.0 3.9 0.04 13.6 0.2 3.7 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.6 EGO56121.1 - 0.00024 21.7 0.0 0.6 10.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGO56121.1 - 0.00025 21.6 0.0 1.3 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain G-alpha PF00503.20 EGO56121.1 - 0.00062 19.0 0.0 0.57 9.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit APS_kinase PF01583.20 EGO56121.1 - 0.00073 19.5 0.2 0.78 9.6 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA PF00004.29 EGO56121.1 - 0.00083 19.8 0.2 4 7.9 0.1 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 EGO56121.1 - 0.00084 19.5 1.3 0.034 14.3 0.0 2.8 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_24 PF13479.6 EGO56121.1 - 0.00085 19.1 0.0 0.35 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EGO56121.1 - 0.0014 18.9 1.4 3.7 7.8 0.5 3.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 EGO56121.1 - 0.0015 18.1 0.3 0.31 10.5 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 EGO56121.1 - 0.0077 15.8 0.0 3.6 7.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF3987 PF13148.6 EGO56121.1 - 0.011 14.8 0.2 3.5 6.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) NB-ARC PF00931.22 EGO56121.1 - 0.012 14.9 0.3 1.7 7.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 EGO56121.1 - 0.013 15.6 3.2 1.1 9.4 0.1 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 EGO56121.1 - 0.013 14.8 0.0 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGO56121.1 - 0.019 14.7 0.1 4.4 7.0 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_17 PF13207.6 EGO56121.1 - 0.021 15.3 0.1 9.6 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGO56121.1 - 0.025 14.6 0.1 10 6.1 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 EGO56121.1 - 0.025 14.2 0.0 4.6 6.8 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.18 EGO56121.1 - 0.029 14.1 2.0 1.3 8.7 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ECH_2 PF16113.5 EGO56121.1 - 0.032 13.7 0.6 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Rif1_N PF12231.8 EGO56121.1 - 0.043 12.8 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal DUF3671 PF12420.8 EGO56121.1 - 0.099 12.7 1.1 0.62 10.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function RNA_helicase PF00910.22 EGO56121.1 - 0.12 12.8 0.1 7.1 7.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.6 EGO56121.1 - 0.19 11.4 0.0 19 4.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Tex_YqgF PF16921.5 EGO56121.1 - 0.21 12.1 1.7 0.41 11.1 0.1 2.4 2 0 0 2 2 1 0 Tex protein YqgF-like domain Rad17 PF03215.15 EGO56121.1 - 0.22 11.4 0.0 5.3 6.9 0.0 2.7 3 0 0 3 3 3 0 Rad17 P-loop domain Acetyltransf_10 PF13673.7 EGO56122.1 - 1.3e-09 38.0 0.0 4.6e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO56122.1 - 6.7e-09 36.0 0.0 1.8e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO56122.1 - 1.6e-08 34.8 0.0 3.9e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGO56122.1 - 0.00076 19.4 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGO56122.1 - 0.045 13.8 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGO56122.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2686 PF10887.8 EGO56122.1 - 0.093 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) SAM_PNT PF02198.16 EGO56122.1 - 0.18 11.8 0.1 0.34 10.9 0.1 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain AMP-binding PF00501.28 EGO56123.1 - 6e-67 226.1 0.2 2.3e-66 224.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 EGO56123.1 - 6.7e-56 189.9 0.0 9.7e-35 120.1 0.0 2.9 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 EGO56123.1 - 8.2e-25 87.0 0.0 4.1e-11 43.1 0.0 3.3 3 0 0 3 3 3 2 Phosphopantetheine attachment site Abhydrolase_1 PF00561.20 EGO56125.1 - 4.5e-10 39.6 0.0 1e-09 38.4 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO56125.1 - 1.3e-07 32.4 0.0 3.4e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO56125.1 - 9.2e-05 21.8 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EthD PF07110.11 EGO56125.1 - 0.00022 22.3 0.5 0.16 13.2 0.0 2.8 3 0 0 3 3 3 2 EthD domain Esterase PF00756.20 EGO56125.1 - 0.0044 16.7 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Putative esterase DUF4286 PF14114.6 EGO56125.1 - 0.021 15.3 0.3 2.3 8.8 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4286) RdRP PF05183.12 EGO56126.1 - 6.4e-185 616.2 0.0 9.1e-185 615.7 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 EGO56126.1 - 0.00059 19.6 0.0 0.0017 18.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Meth_synt_2 PF01717.18 EGO56127.1 - 5.6e-09 35.7 0.0 9.3e-05 21.8 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EGO56127.1 - 0.0026 17.3 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 Cobalamin-independent synthase, N-terminal domain DUF998 PF06197.13 EGO56128.1 - 1.8 8.1 13.3 0.081 12.5 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF998) CDH-cyt PF16010.5 EGO56129.1 - 1.2e-47 161.9 2.4 1.5e-47 161.7 2.4 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF1211 PF06736.11 EGO56133.1 - 0.68 10.4 4.2 0.69 10.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) DUF2231 PF09990.9 EGO56133.1 - 1.8 9.0 6.2 0.16 12.4 0.9 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) MFS_1 PF07690.16 EGO56134.1 - 5.1e-38 130.9 31.5 1.2e-37 129.7 30.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Rep_fac_C PF08542.11 EGO56135.1 - 3.4e-17 62.6 0.1 9.6e-17 61.2 0.1 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EGO56135.1 - 1.3e-16 61.2 0.1 4.2e-16 59.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGO56135.1 - 6e-13 48.9 0.0 1.9e-12 47.3 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 EGO56135.1 - 3.9e-07 30.3 0.2 1.2e-06 28.7 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA_30 PF13604.6 EGO56135.1 - 1.9e-06 27.8 0.0 5.4e-06 26.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.6 EGO56135.1 - 2.9e-06 27.3 0.2 0.00017 21.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 EGO56135.1 - 5.7e-06 26.4 0.0 9.8e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EGO56135.1 - 6.5e-06 26.6 0.0 3.5e-05 24.2 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGO56135.1 - 1.7e-05 25.1 0.0 5.8e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGO56135.1 - 3.2e-05 23.7 0.0 9.7e-05 22.2 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 EGO56135.1 - 3.9e-05 23.5 0.0 7.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF815 PF05673.13 EGO56135.1 - 0.00018 20.8 0.0 0.00041 19.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 EGO56135.1 - 0.00022 21.0 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EGO56135.1 - 0.00025 21.1 0.0 0.021 14.9 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 EGO56135.1 - 0.00041 20.2 0.2 0.002 18.0 0.1 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGO56135.1 - 0.00082 19.4 0.0 0.002 18.2 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 EGO56135.1 - 0.0009 19.3 0.5 0.004 17.2 0.2 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.16 EGO56135.1 - 0.0015 18.1 0.6 0.32 10.4 0.0 2.7 2 1 1 3 3 3 1 PhoH-like protein AAA_19 PF13245.6 EGO56135.1 - 0.0035 17.7 0.1 0.0081 16.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EGO56135.1 - 0.0051 16.6 0.1 0.04 13.7 0.1 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase Mg_chelatase PF01078.21 EGO56135.1 - 0.021 14.2 0.0 0.13 11.6 0.0 2.4 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGO56135.1 - 0.021 15.1 0.0 0.039 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGO56135.1 - 0.023 14.2 0.0 0.058 12.9 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 EGO56135.1 - 0.028 13.8 0.0 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 EGO56135.1 - 0.038 14.4 0.0 0.079 13.4 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EGO56135.1 - 0.13 12.8 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EGO56135.1 - 0.19 11.0 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HET PF06985.11 EGO56136.1 - 2.6e-31 109.0 0.1 4.6e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SelK_SelG PF10961.8 EGO56137.1 - 0.044 14.4 0.4 0.044 14.4 0.4 2.8 4 0 0 4 4 4 0 Selenoprotein SelK_SelG CorA PF01544.18 EGO56137.1 - 0.1 11.9 0.4 0.21 10.9 0.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Ecl1 PF12855.7 EGO56137.1 - 1 10.5 11.3 1.9 9.6 11.3 1.4 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins MFS_1 PF07690.16 EGO56138.1 - 3.4e-32 111.8 46.3 5.6e-22 78.1 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGO56138.1 - 1.5e-07 30.3 26.7 9.6e-06 24.4 11.0 3.1 2 2 1 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.7 EGO56138.1 - 3.1e-05 23.0 11.0 0.00034 19.6 6.5 2.5 2 1 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 EGO56138.1 - 6.8e-05 21.9 19.3 0.00028 19.9 9.8 3.6 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EGO56138.1 - 0.0012 17.3 3.1 0.0029 16.1 3.1 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 EGO56138.1 - 0.081 11.8 4.5 0.021 13.7 1.6 1.5 2 0 0 2 2 2 0 Sugar-tranasporters, 12 TM OATP PF03137.20 EGO56138.1 - 0.17 10.1 12.4 0.75 8.0 2.0 3.3 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EGO56138.1 - 8.4 4.7 18.8 0.1 11.0 6.8 2.4 2 1 0 2 2 2 0 Transmembrane secretion effector Bromodomain PF00439.25 EGO56141.1 - 4.5e-37 126.0 0.1 3.7e-21 75.0 0.3 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 EGO56141.1 - 2.8e-14 53.0 0.3 7.5e-14 51.7 0.3 1.8 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation FOXP-CC PF16159.5 EGO56141.1 - 1.4 9.6 4.1 2.1 9.1 1.5 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain DHR10 PF18595.1 EGO56141.1 - 2 8.5 10.9 2.1 8.4 1.9 3.7 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Utp12 PF04003.12 EGO56142.1 - 2.5e-22 79.2 0.0 3.5e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family SDA1 PF05285.12 EGO56142.1 - 0.11 11.8 53.9 0.21 11.0 33.7 2.4 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 EGO56142.1 - 6 6.1 54.0 0.94 8.7 31.6 2.1 2 0 0 2 2 2 0 BUD22 Pro-kuma_activ PF09286.11 EGO56145.1 - 4.1e-37 127.6 0.1 8.1e-37 126.7 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGO56145.1 - 2.7e-06 26.9 0.0 8.3e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 Subtilase family Rhabdo_ncap PF00945.18 EGO56145.1 - 0.17 10.7 0.1 0.27 10.1 0.1 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Rxt3 PF08642.10 EGO56146.1 - 3.1e-28 99.1 0.3 4.8e-15 56.5 0.2 6.7 5 2 1 6 6 6 2 Histone deacetylation protein Rxt3 LCCL PF03815.19 EGO56146.1 - 7.8e-05 22.7 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 LCCL domain DUF1674 PF07896.12 EGO56147.1 - 1.9e-17 63.5 8.5 6.6e-17 61.7 8.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Retinal PF15449.6 EGO56147.1 - 0.88 7.3 6.3 0.95 7.2 6.3 1.0 1 0 0 1 1 1 0 Retinal protein Pkinase PF00069.25 EGO56148.1 - 7.3e-30 104.2 0.0 1.8e-29 102.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO56148.1 - 1.3e-16 60.7 0.0 1.8e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO56148.1 - 3.5e-06 26.1 0.0 4.8e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGO56148.1 - 0.0075 16.2 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGO56148.1 - 0.017 14.5 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acetyltransf_1 PF00583.25 EGO56149.1 - 6.1e-05 23.2 0.0 0.00011 22.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO56149.1 - 0.00013 22.3 0.2 0.00035 20.9 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGO56149.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGO56149.1 - 0.0092 16.1 0.1 0.021 14.9 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cellulase PF00150.18 EGO56151.1 - 2.8e-19 69.7 3.0 4.2e-19 69.1 3.0 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EGO56151.1 - 2.2e-05 23.7 0.0 8.4e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 EGO56151.1 - 0.00012 21.6 0.2 0.00074 19.0 0.2 2.0 1 1 0 1 1 1 1 Beta-galactosidase Hfq PF17209.3 EGO56151.1 - 0.0046 16.6 0.2 0.012 15.2 0.1 1.7 2 0 0 2 2 2 1 Hfq protein Aminotran_1_2 PF00155.21 EGO56153.1 - 1.6e-93 313.8 0.0 1.8e-93 313.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Ribosomal_L28 PF00830.19 EGO56154.1 - 1.8e-20 72.9 3.8 2.8e-20 72.2 3.8 1.3 1 0 0 1 1 1 1 Ribosomal L28 family DUF4618 PF15397.6 EGO56155.1 - 0.0085 15.5 0.3 0.014 14.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) Trp_syntA PF00290.20 EGO56156.1 - 1.2e-103 345.5 0.1 2.6e-103 344.4 0.0 1.6 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 EGO56156.1 - 1.5e-49 169.0 0.4 2.4e-49 168.3 0.4 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CLN3 PF02487.17 EGO56157.1 - 3.4e-165 549.9 8.1 4e-165 549.7 8.1 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 EGO56157.1 - 3.9e-06 26.0 26.2 5.4e-06 25.6 6.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4360 PF14273.6 EGO56158.1 - 0.0021 18.0 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MFS_1 PF07690.16 EGO56159.1 - 4.2e-38 131.2 25.0 5.8e-38 130.7 25.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGO56159.1 - 0.18 11.5 7.2 0.024 14.4 2.3 2.0 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 adh_short PF00106.25 EGO56160.1 - 2.5e-15 56.5 0.2 6.3e-15 55.1 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO56160.1 - 6.5e-07 29.1 0.0 1.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO56160.1 - 6.1e-06 26.3 0.1 1e-05 25.6 0.1 1.3 1 0 0 1 1 1 1 KR domain IBR PF01485.21 EGO56161.1 - 4.6e-11 42.8 45.2 5.9e-08 32.8 2.8 4.4 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EGO56161.1 - 0.0051 17.1 11.1 0.0051 17.1 11.1 5.5 4 2 1 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO56161.1 - 0.01 15.7 7.7 0.01 15.7 7.7 5.7 5 2 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) AMP-binding PF00501.28 EGO56162.1 - 1.2e-62 211.9 0.0 1.9e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EGO56162.1 - 5.9e-15 55.4 0.4 1.3e-14 54.3 0.4 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 EGO56162.1 - 4.7e-06 26.1 5.3 0.029 14.1 0.0 6.1 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGO56162.1 - 1.2 8.9 14.6 6.3 6.6 1.0 5.3 5 1 1 6 6 6 0 Hexapeptide repeat of succinyl-transferase F-box PF00646.33 EGO56163.1 - 0.00022 21.0 0.2 0.00022 21.0 0.2 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EGO56163.1 - 0.0038 17.1 0.3 0.01 15.7 0.3 1.8 1 0 0 1 1 1 1 F-box-like ADH_N PF08240.12 EGO56164.1 - 7.6e-23 80.5 8.3 1.3e-22 79.8 8.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO56164.1 - 2.4e-17 63.1 0.0 4.8e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGO56164.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EGO56164.1 - 0.026 13.9 0.3 0.04 13.3 0.3 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FHA PF00498.26 EGO56164.1 - 0.16 12.4 0.1 0.34 11.3 0.1 1.5 1 0 0 1 1 1 0 FHA domain KR PF08659.10 EGO56164.1 - 0.2 11.6 0.2 0.39 10.6 0.2 1.4 1 0 0 1 1 1 0 KR domain FAD_binding_4 PF01565.23 EGO56165.1 - 5.9e-18 64.9 1.6 1.1e-17 64.1 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGO56165.1 - 7.6e-11 41.9 0.3 1.9e-10 40.6 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like Pyr_redox_3 PF13738.6 EGO56166.1 - 1.6e-17 63.7 0.0 3.9e-15 55.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO56166.1 - 2.1e-15 56.7 0.0 1.2e-10 41.1 0.0 3.1 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 EGO56166.1 - 6.7e-13 47.9 0.0 2.4e-11 42.8 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGO56166.1 - 1.2e-09 37.8 0.0 1.7e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO56166.1 - 9.9e-08 32.1 2.3 6.6e-06 26.2 0.1 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 EGO56166.1 - 3.6e-06 26.4 0.0 6.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EGO56166.1 - 5.3e-06 26.6 0.0 1.6e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO56166.1 - 0.00015 21.4 0.0 0.0074 15.9 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGO56166.1 - 0.00018 20.4 0.0 0.019 13.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 EGO56166.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO56166.1 - 0.043 12.9 0.1 0.51 9.4 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 EGO56166.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EGO56166.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.16 EGO56167.1 - 1.6e-12 47.0 37.0 3.9e-09 35.9 27.5 2.5 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO56167.1 - 0.00057 18.9 13.6 0.0065 15.4 0.7 3.4 2 1 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 EGO56167.1 - 1.2 7.3 9.6 1.3 7.2 0.0 3.4 3 1 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DUF2417 PF10329.9 EGO56167.1 - 1.2 8.5 3.7 1.9 7.9 0.2 2.3 2 0 0 2 2 2 0 Region of unknown function (DUF2417) FMO-like PF00743.19 EGO56168.1 - 9e-13 47.5 0.0 5.1e-11 41.7 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EGO56168.1 - 5.5e-11 42.5 0.0 1.7e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGO56168.1 - 3.7e-08 33.0 0.0 2.5e-06 27.0 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO56168.1 - 1.8e-06 27.4 0.0 5.1e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO56168.1 - 0.00011 22.0 0.0 0.057 13.0 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 EGO56168.1 - 0.00014 21.1 0.0 0.95 8.5 0.0 3.5 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EGO56168.1 - 0.019 14.2 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EGO56168.1 - 0.02 14.9 0.0 0.051 13.6 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EGO56168.1 - 0.031 13.4 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EGO56168.1 - 0.032 14.8 0.0 2.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EGO56168.1 - 0.074 12.4 0.0 0.72 9.2 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LBR_tudor PF09465.10 EGO56168.1 - 0.25 11.2 1.7 0.6 10.0 0.1 2.5 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain CBM_20 PF00686.19 EGO56169.1 - 1.8e-33 114.3 0.7 3.4e-33 113.4 0.7 1.4 1 0 0 1 1 1 1 Starch binding domain LPMO_10 PF03067.15 EGO56169.1 - 2.6e-10 41.3 2.6 4.9e-10 40.4 2.6 1.5 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 EGO56169.1 - 3.4e-05 23.9 0.3 0.0021 18.1 0.1 2.5 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 CVNH PF08881.10 EGO56170.1 - 1.4e-05 25.7 0.6 0.0001 22.9 0.6 2.1 1 1 0 1 1 1 1 CVNH domain DM4_12 PF07841.13 EGO56170.1 - 0.032 14.9 1.0 0.18 12.5 0.1 2.3 2 1 1 3 3 3 0 DM4/DM12 family bZIP_1 PF00170.21 EGO56171.1 - 7.4e-07 29.2 4.9 2e-06 27.8 4.9 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGO56171.1 - 3.1e-05 24.0 6.3 6.1e-05 23.0 6.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Desmo_N PF06771.11 EGO56171.1 - 0.098 13.0 0.1 0.28 11.6 0.1 1.7 1 1 0 1 1 1 0 Viral Desmoplakin N-terminus Lebercilin PF15619.6 EGO56171.1 - 0.14 11.8 11.8 0.23 11.1 11.8 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_Maf PF03131.17 EGO56171.1 - 1.5 9.4 11.0 0.07 13.6 4.9 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor Pho88 PF10032.9 EGO56172.1 - 3e-80 267.8 0.0 3.4e-80 267.6 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) XPA_C PF05181.12 EGO56173.1 - 2e-25 88.5 5.1 2.6e-25 88.1 2.7 2.2 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.18 EGO56173.1 - 6.6e-05 22.9 2.5 6.6e-05 22.9 2.5 1.7 2 0 0 2 2 2 1 XPA protein N-terminal ArfGap PF01412.18 EGO56173.1 - 0.076 13.1 0.7 0.076 13.1 0.7 2.0 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Striatin PF08232.12 EGO56174.1 - 3.3e-43 148.0 7.0 3.3e-43 148.0 7.0 2.6 2 1 0 2 2 2 1 Striatin family WD40 PF00400.32 EGO56174.1 - 1.4e-23 82.7 21.1 6.5e-05 23.6 0.2 8.0 8 1 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO56174.1 - 4.9e-07 30.0 0.0 0.045 14.1 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Polysacc_deac_1 PF01522.21 EGO56174.1 - 0.047 13.6 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase PTR2 PF00854.21 EGO56175.1 - 2.9e-45 154.8 0.3 3.9e-45 154.4 0.3 1.1 1 0 0 1 1 1 1 POT family Asp PF00026.23 EGO56177.1 - 1e-75 255.1 4.1 1.3e-75 254.7 4.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO56177.1 - 9.1e-14 52.1 2.2 7.4e-08 32.8 0.0 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO56177.1 - 0.0015 19.2 0.6 0.034 14.8 0.2 2.9 2 1 0 2 2 2 1 Aspartyl protease HET PF06985.11 EGO56178.1 - 1.7e-24 86.8 2.0 1.7e-24 86.8 2.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) CTP_transf_like PF01467.26 EGO56179.1 - 0.011 16.0 0.0 0.04 14.1 0.0 2.0 1 1 0 1 1 1 0 Cytidylyltransferase-like Rubis-subs-bind PF09273.11 EGO56181.1 - 3.2e-23 82.8 0.0 6.2e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EGO56181.1 - 4.6e-16 59.7 0.0 6.9e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGO56181.1 - 1.3e-09 38.0 14.2 2.2e-09 37.3 14.2 1.4 1 0 0 1 1 1 1 MYND finger Gln-synt_N_2 PF16952.5 EGO56181.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain Tudor_4 PF18358.1 EGO56182.1 - 0.0069 16.0 0.6 0.024 14.2 0.6 1.9 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain HET PF06985.11 EGO56183.1 - 3.1e-17 63.3 0.0 6.3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4834 PF16118.5 EGO56184.1 - 0.0023 18.8 2.6 0.003 18.5 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Methyltransf_23 PF13489.6 EGO56184.1 - 0.0044 16.9 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF2722 PF10846.8 EGO56184.1 - 0.0065 15.5 20.3 0.0074 15.3 20.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 EGO56184.1 - 0.01 15.4 24.8 0.015 14.9 24.8 1.2 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 EGO56184.1 - 0.013 15.5 9.2 0.015 15.3 9.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) INSIG PF07281.12 EGO56184.1 - 0.023 14.3 0.1 0.039 13.6 0.1 1.3 1 1 0 1 1 1 0 Insulin-induced protein (INSIG) ANAPC_CDC26 PF10471.9 EGO56184.1 - 0.043 14.7 20.6 0.079 13.8 20.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 BBL5 PF07289.11 EGO56184.1 - 0.046 12.8 2.1 0.055 12.5 2.1 1.1 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein TFIIA PF03153.13 EGO56184.1 - 0.049 13.6 20.2 0.055 13.5 20.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF775 PF05603.12 EGO56184.1 - 0.051 13.1 5.1 0.06 12.9 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF3464 PF11947.8 EGO56184.1 - 0.083 12.6 5.1 0.1 12.3 5.1 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Rxt3 PF08642.10 EGO56184.1 - 0.12 13.1 1.9 0.16 12.7 1.9 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 SKA1 PF07160.12 EGO56184.1 - 0.16 11.8 7.8 0.21 11.4 7.8 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Neur_chan_memb PF02932.16 EGO56184.1 - 0.17 11.9 3.1 0.18 11.8 3.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Roughex PF06020.11 EGO56184.1 - 0.19 10.8 8.1 0.24 10.5 8.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 EGO56184.1 - 0.22 10.3 5.1 0.25 10.1 5.1 1.1 1 0 0 1 1 1 0 Presenilin DUF702 PF05142.12 EGO56184.1 - 0.24 11.9 7.5 0.32 11.5 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) eIF-3_zeta PF05091.12 EGO56184.1 - 0.25 10.3 7.8 0.3 10.0 7.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4175 PF13779.6 EGO56184.1 - 0.33 8.8 15.8 0.38 8.6 15.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CobT PF06213.12 EGO56184.1 - 0.34 10.3 9.0 0.41 10.0 9.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Otopetrin PF03189.13 EGO56184.1 - 0.39 9.5 3.3 0.47 9.2 3.3 1.1 1 0 0 1 1 1 0 Otopetrin Pex14_N PF04695.13 EGO56184.1 - 0.44 11.2 13.3 0.59 10.8 13.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4407 PF14362.6 EGO56184.1 - 0.6 9.4 4.9 0.73 9.1 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MMR1 PF08505.10 EGO56184.1 - 0.67 10.2 12.4 0.85 9.9 12.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein EIIBC-GUT_N PF03612.14 EGO56184.1 - 0.71 9.6 3.9 0.9 9.2 3.9 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TERB2 PF15101.6 EGO56184.1 - 0.78 9.8 10.2 0.94 9.5 10.2 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ctr PF04145.15 EGO56184.1 - 1.1 9.9 3.6 1.6 9.4 3.6 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF5349 PF17298.2 EGO56184.1 - 1.4 8.6 13.8 1.7 8.3 13.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) UPF0560 PF10577.9 EGO56184.1 - 1.5 7.2 11.7 1.7 7.1 11.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Androgen_recep PF02166.16 EGO56184.1 - 6.4 5.5 22.5 7.6 5.3 22.5 1.1 1 0 0 1 1 1 0 Androgen receptor Fox-1_C PF12414.8 EGO56185.1 - 0.11 12.9 5.5 0.14 12.5 1.8 2.1 1 1 1 2 2 2 0 Calcitonin gene-related peptide regulator C terminal TMEM52 PF14979.6 EGO56187.1 - 0.019 14.9 0.1 0.042 13.8 0.1 1.5 1 0 0 1 1 1 0 Transmembrane 52 ANAPC10 PF03256.16 EGO56190.1 - 9.1e-48 162.4 0.0 1.3e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PITH PF06201.13 EGO56190.1 - 0.15 12.3 0.0 0.51 10.5 0.0 1.8 1 1 0 1 1 1 0 PITH domain Mre11_DNA_bind PF04152.14 EGO56192.1 - 4.5e-52 176.8 0.3 4.5e-52 176.8 0.3 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EGO56192.1 - 4.3e-16 60.0 1.6 7.6e-16 59.2 1.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGO56192.1 - 1.6e-05 25.2 0.0 9.2e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TFIID_30kDa PF03540.13 EGO56193.1 - 3.2e-25 87.8 0.4 6.2e-25 86.9 0.4 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TAF4 PF05236.14 EGO56193.1 - 0.097 12.4 0.0 0.85 9.3 0.0 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Ribosomal_S19 PF00203.21 EGO56194.1 - 1.1e-27 95.7 0.0 1.4e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Zn_clus PF00172.18 EGO56196.1 - 9.3e-08 32.1 13.6 1.7e-07 31.2 13.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WXG100 PF06013.12 EGO56198.1 - 0.64 10.3 2.8 2.3 8.5 0.4 2.2 1 1 1 2 2 2 0 Proteins of 100 residues with WXG CVNH PF08881.10 EGO56199.1 - 2.3e-05 25.0 0.1 3.1e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 CVNH domain CVNH PF08881.10 EGO56200.1 - 0.0023 18.6 3.7 0.18 12.5 3.7 2.8 1 1 0 1 1 1 1 CVNH domain HET PF06985.11 EGO56201.1 - 2.1e-25 89.8 0.1 4.1e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AltA1 PF16541.5 EGO56203.1 - 6.5e-24 84.9 1.7 9.6e-24 84.4 1.7 1.3 1 0 0 1 1 1 1 Alternaria alternata allergen 1 Amidase PF01425.21 EGO56204.1 - 2.4e-68 231.2 0.5 9.8e-67 225.8 0.0 2.3 2 0 0 2 2 2 2 Amidase F-box-like PF12937.7 EGO56206.1 - 0.0014 18.5 0.7 0.0051 16.7 0.7 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO56206.1 - 0.0041 17.0 2.3 0.013 15.3 2.3 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 EGO56206.1 - 0.047 14.1 0.1 69 4.1 0.0 4.1 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) p450 PF00067.22 EGO56207.1 - 3.8e-48 164.4 0.0 1.5e-47 162.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EGO56208.1 - 2.3e-41 141.9 28.3 3.1e-41 141.5 28.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2127 PF09900.9 EGO56208.1 - 0.0077 16.5 1.6 0.37 11.1 0.3 3.2 3 0 0 3 3 3 1 Predicted membrane protein (DUF2127) DUF1992 PF09350.10 EGO56211.1 - 4.2e-21 74.9 0.6 1.4e-20 73.2 0.6 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DUF896 PF05979.12 EGO56211.1 - 0.055 13.4 0.3 3.1 7.7 0.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Cytotoxic PF09000.10 EGO56213.1 - 0.072 13.4 0.2 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 Cytotoxic DUF1741 PF08427.10 EGO56214.1 - 2.4e-85 285.9 0.8 1e-84 283.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Fe-S_biosyn PF01521.20 EGO56215.1 - 1.3e-19 70.4 0.0 1.8e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis CPT_N PF16484.5 EGO56215.1 - 0.035 14.1 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus Ndc1_Nup PF09531.10 EGO56215.1 - 1.1 7.8 7.0 1.2 7.8 7.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 EGO56215.1 - 2.5 8.0 10.0 3 7.7 10.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.9 EGO56215.1 - 3.2 6.5 6.1 4 6.2 6.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MgsA_C PF12002.8 EGO56216.1 - 3.4e-60 202.8 0.0 5.6e-60 202.1 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EGO56216.1 - 1.1e-23 83.4 0.0 2.6e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EGO56216.1 - 8e-13 49.0 0.0 1.5e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGO56216.1 - 2.3e-08 33.9 0.0 4.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EGO56216.1 - 5e-06 26.3 0.0 0.00031 20.5 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EGO56216.1 - 2.6e-05 24.7 1.2 0.0092 16.4 0.0 3.1 1 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 EGO56216.1 - 0.00056 20.0 0.0 0.00097 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGO56216.1 - 0.0011 19.2 0.3 0.0053 17.0 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGO56216.1 - 0.0012 18.9 0.1 0.053 13.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGO56216.1 - 0.0012 18.3 0.0 0.64 9.4 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EGO56216.1 - 0.0042 16.3 0.0 0.0071 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DNA_pol3_delta2 PF13177.6 EGO56216.1 - 0.006 16.4 0.0 0.13 12.0 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_19 PF13245.6 EGO56216.1 - 0.026 14.8 0.2 0.12 12.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 EGO56216.1 - 0.029 13.6 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain SKI PF01202.22 EGO56216.1 - 0.034 14.3 0.1 0.064 13.4 0.1 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_3 PF07726.11 EGO56216.1 - 0.048 13.5 0.0 0.15 11.9 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EGO56216.1 - 0.056 13.4 0.7 2 8.4 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 EGO56216.1 - 0.062 13.5 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGO56216.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 EGO56216.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TniB PF05621.11 EGO56216.1 - 0.13 11.7 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_23 PF13476.6 EGO56216.1 - 0.17 12.4 0.1 0.28 11.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EGO56216.1 - 0.17 11.6 0.1 0.87 9.3 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase HeLo PF14479.6 EGO56217.1 - 5.9e-51 173.2 0.5 1.2e-50 172.2 0.1 1.8 2 0 0 2 2 2 1 Prion-inhibition and propagation NACHT PF05729.12 EGO56217.1 - 8.4e-07 29.0 0.0 3.9e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGO56217.1 - 1.6e-06 28.6 0.0 1e-05 26.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGO56217.1 - 0.0021 18.4 0.0 0.0066 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGO56217.1 - 0.0053 16.7 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 EGO56217.1 - 0.037 14.5 0.0 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 EGO56217.1 - 0.052 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EGO56217.1 - 0.056 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EGO56217.1 - 0.07 13.7 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGO56217.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EGO56217.1 - 0.14 11.9 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pyrophosphatase PF00719.19 EGO56219.1 - 6.6e-51 172.3 0.0 9.5e-51 171.8 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase SR-25 PF10500.9 EGO56219.1 - 0.0082 15.8 18.3 0.013 15.1 18.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 EGO56219.1 - 1.9 9.3 8.7 4.5 8.2 8.7 1.5 1 0 0 1 1 1 0 Chorion family 2 AAA_23 PF13476.6 EGO56220.1 - 2.2 8.7 15.9 1.2 9.6 1.2 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGO56221.1 - 1e-05 25.6 0.0 2.9e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO56221.1 - 0.00068 19.6 0.0 0.0021 18.0 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase fn3 PF00041.21 EGO56221.1 - 0.0058 16.9 0.0 0.036 14.4 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III domain AAA_29 PF13555.6 EGO56221.1 - 0.011 15.4 0.1 0.028 14.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EGO56221.1 - 0.02 15.4 0.2 0.18 12.3 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 EGO56221.1 - 0.21 12.1 0.0 0.21 12.1 0.0 2.8 3 1 0 3 3 3 0 AAA domain Cnn_1N PF07989.11 EGO56222.1 - 8e-05 22.7 18.3 9.9e-05 22.4 17.2 1.8 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 AAA_23 PF13476.6 EGO56222.1 - 0.21 12.1 4.8 0.38 11.2 4.8 1.4 1 0 0 1 1 1 0 AAA domain ADIP PF11559.8 EGO56222.1 - 7.8 6.6 16.0 1.1 9.3 11.2 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding MOR2-PAG1_mid PF14228.6 EGO56223.1 - 0.2 9.2 0.0 0.25 8.9 0.0 1.0 1 0 0 1 1 1 0 Cell morphogenesis central region adh_short PF00106.25 EGO56224.1 - 3e-23 82.3 0.2 2.2e-22 79.5 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO56224.1 - 3e-12 46.6 0.1 6.3e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO56224.1 - 1.9e-07 31.2 0.1 7.2e-07 29.3 0.0 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 EGO56224.1 - 0.028 13.9 0.1 0.11 11.9 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CorA PF01544.18 EGO56225.1 - 3.4e-11 43.0 0.5 7.7e-11 41.8 0.5 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein EMP70 PF02990.16 EGO56225.1 - 0.039 12.6 1.3 0.79 8.3 1.3 2.0 1 1 1 2 2 2 0 Endomembrane protein 70 Peptidase_S49_N PF08496.10 EGO56225.1 - 0.12 12.5 0.0 0.12 12.5 0.0 2.1 2 1 0 2 2 2 0 Peptidase family S49 N-terminal FRB_dom PF08771.11 EGO56226.1 - 0.44 11.0 3.3 1.2 9.6 0.0 3.4 4 0 0 4 4 4 0 FKBP12-rapamycin binding domain DUF2681 PF10883.8 EGO56226.1 - 6.8 7.2 7.9 1.7 9.1 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Cytochrom_B561 PF03188.16 EGO56228.1 - 3.4e-07 30.5 13.3 5.9e-07 29.7 13.3 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 EGO56228.1 - 2.1e-06 27.4 5.8 4.2e-06 26.5 5.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF1673 PF07895.11 EGO56228.1 - 0.14 11.8 0.3 0.24 11.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) 7TMR-DISM_7TM PF07695.11 EGO56228.1 - 0.98 9.3 10.5 0.75 9.7 4.8 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling Nop14 PF04147.12 EGO56229.1 - 3.6 5.7 14.8 7 4.7 14.8 1.4 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 EGO56229.1 - 4 7.0 13.1 13 5.3 13.1 1.9 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 EGO56229.1 - 5.2 5.1 27.0 8.6 4.3 27.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF1040 PF06288.13 EGO56230.1 - 0.036 14.4 1.7 0.079 13.3 1.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1040) DUF2464 PF10240.9 EGO56230.1 - 8.1 5.9 8.0 0.82 9.2 0.9 2.7 2 0 0 2 2 2 0 Multivesicular body subunit 12 NACHT_N PF17100.5 EGO56234.1 - 5.9e-09 36.1 0.0 7.8e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase LisH PF08513.11 EGO56234.1 - 0.025 14.6 0.1 0.068 13.2 0.1 1.7 1 0 0 1 1 1 0 LisH AIP3 PF03915.13 EGO56243.1 - 4.6e-161 536.5 9.6 9.1e-161 535.5 9.6 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.14 EGO56243.1 - 0.0061 16.3 6.7 0.015 15.0 0.2 3.3 3 1 0 3 3 3 1 Hepatic lectin, N-terminal domain TraF_2 PF13729.6 EGO56243.1 - 0.11 11.8 0.7 2.4 7.5 0.1 2.3 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein DUF1664 PF07889.12 EGO56243.1 - 0.12 12.4 8.8 2.3 8.2 2.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 EGO56243.1 - 0.47 10.8 10.9 11 6.4 2.0 4.6 3 1 0 3 3 3 0 Syntaxin-like protein Prominin PF05478.11 EGO56243.1 - 5.1 4.9 4.9 19 3.0 1.2 2.4 2 0 0 2 2 2 0 Prominin Beta-lactamase PF00144.24 EGO56244.1 - 7.8e-30 104.2 1.5 1.5e-29 103.3 1.5 1.4 1 1 0 1 1 1 1 Beta-lactamase HET PF06985.11 EGO56245.1 - 1.6e-05 25.3 0.1 1.8e-05 25.2 0.1 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ATP-grasp_2 PF08442.10 EGO56246.1 - 2.6e-77 259.0 0.6 2.6e-77 259.0 0.6 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EGO56246.1 - 3.9e-26 91.7 0.2 7.2e-26 90.8 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EGO56246.1 - 1.6e-10 40.8 0.1 3.6e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EGO56246.1 - 0.0084 15.9 0.3 0.26 11.0 0.0 2.4 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Serglycin PF04360.12 EGO56247.1 - 3.7 7.5 6.4 11 6.0 6.4 1.7 1 0 0 1 1 1 0 Serglycin HET PF06985.11 EGO56248.1 - 5.9e-12 46.2 6.7 1.1e-09 38.8 0.7 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) IES5 PF17335.2 EGO56248.1 - 0.17 12.1 0.1 0.36 11.1 0.1 1.5 1 0 0 1 1 1 0 Ino80 complex subunit 5 Glyco_hydro_71 PF03659.14 EGO56249.1 - 3e-122 408.1 5.1 6.1e-122 407.1 5.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 HET PF06985.11 EGO56250.1 - 0.00011 22.5 0.1 0.00012 22.5 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SET PF00856.28 EGO56251.1 - 0.00024 21.6 0.3 0.0031 17.9 0.0 2.1 2 0 0 2 2 2 1 SET domain Ribosomal_60s PF00428.19 EGO56251.1 - 0.044 14.4 4.9 0.086 13.4 4.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein MAP PF03642.13 EGO56251.1 - 0.18 12.1 0.0 0.54 10.6 0.0 1.7 2 0 0 2 2 2 0 MAP domain MMU163 PF17119.5 EGO56252.1 - 4.9e-81 271.5 1.4 2.9e-80 269.0 1.4 1.9 1 1 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis Tom5 PF10642.9 EGO56252.1 - 0.083 12.9 0.3 0.16 12.0 0.3 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Ras PF00071.22 EGO56253.1 - 2.1e-65 219.3 0.6 2.5e-65 219.0 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO56253.1 - 7e-36 123.1 0.1 1.3e-35 122.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO56253.1 - 2.9e-16 59.4 0.1 3.5e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGO56253.1 - 7.4e-06 26.0 0.4 0.12 12.2 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGO56253.1 - 1.6e-05 25.0 0.0 0.00011 22.3 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO56253.1 - 3.9e-05 23.3 0.6 0.0001 21.9 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGO56253.1 - 0.00023 20.6 0.1 0.00031 20.2 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGO56253.1 - 0.00045 19.7 0.1 0.00079 18.9 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 EGO56253.1 - 0.0018 18.7 0.0 0.14 12.6 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 EGO56253.1 - 0.0031 17.1 0.1 0.019 14.5 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EGO56253.1 - 0.0099 16.3 0.0 0.014 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 EGO56253.1 - 0.038 13.3 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 EGO56253.1 - 0.038 14.3 0.0 0.068 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain LANC_like PF05147.13 EGO56253.1 - 0.048 12.2 0.1 0.15 10.6 0.0 1.8 1 1 1 2 2 2 0 Lanthionine synthetase C-like protein AAA_29 PF13555.6 EGO56253.1 - 0.053 13.3 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 EGO56253.1 - 0.069 12.6 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 EGO56253.1 - 0.072 13.1 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGO56253.1 - 0.078 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EGO56253.1 - 0.11 13.1 0.0 0.16 12.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 EGO56253.1 - 0.11 12.3 0.1 1.3 8.8 0.0 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2828 PF11443.8 EGO56254.1 - 2.7e-05 22.5 19.2 2.9e-05 22.4 19.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) PTPRCAP PF15713.5 EGO56254.1 - 0.0023 18.3 8.8 0.0029 17.9 8.8 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated SpoIIP PF07454.11 EGO56254.1 - 0.0037 16.8 15.8 0.0051 16.3 15.8 1.3 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DUF3807 PF12720.7 EGO56254.1 - 0.0043 17.4 30.7 0.0052 17.1 30.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Vfa1 PF08432.10 EGO56254.1 - 0.009 16.4 35.6 0.012 16.0 35.6 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF4776 PF16003.5 EGO56254.1 - 0.014 14.4 26.9 0.015 14.3 26.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) YL1 PF05764.13 EGO56254.1 - 0.034 14.3 40.2 0.051 13.7 40.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Otopetrin PF03189.13 EGO56254.1 - 0.037 12.8 3.2 0.043 12.7 3.2 1.1 1 0 0 1 1 1 0 Otopetrin CDC45 PF02724.14 EGO56254.1 - 0.039 12.3 24.7 0.047 12.0 24.7 1.0 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.6 EGO56254.1 - 0.046 13.9 25.0 0.089 13.0 25.0 1.5 1 0 0 1 1 1 0 YqfQ-like protein DUF913 PF06025.12 EGO56254.1 - 0.062 12.3 7.2 0.066 12.2 7.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RP-C_C PF11800.8 EGO56254.1 - 0.064 13.3 6.0 0.076 13.1 6.0 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DAG_kinase_N PF14513.6 EGO56254.1 - 0.066 13.4 14.5 0.084 13.1 14.5 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF2052 PF09747.9 EGO56254.1 - 0.078 13.1 17.5 0.099 12.8 17.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Tim54 PF11711.8 EGO56254.1 - 0.078 11.7 20.6 0.1 11.4 20.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AAA_11 PF13086.6 EGO56254.1 - 0.087 12.6 18.8 0.096 12.5 18.8 1.1 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.12 EGO56254.1 - 0.088 12.6 29.8 0.11 12.3 29.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 EGO56254.1 - 0.12 11.4 20.0 0.13 11.2 20.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SCAI PF12070.8 EGO56254.1 - 0.13 11.1 10.4 0.17 10.7 10.4 1.1 1 0 0 1 1 1 0 Protein SCAI Serinc PF03348.15 EGO56254.1 - 0.2 10.5 5.3 0.22 10.4 5.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Zip PF02535.22 EGO56254.1 - 0.25 10.5 11.8 0.29 10.3 11.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4746 PF15928.5 EGO56254.1 - 0.35 10.2 14.1 0.52 9.7 14.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 EGO56254.1 - 0.4 9.4 18.1 0.47 9.2 18.1 1.1 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 EGO56254.1 - 0.52 9.3 10.1 0.59 9.1 10.1 1.1 1 0 0 1 1 1 0 CLN3 protein LicD PF04991.13 EGO56254.1 - 0.6 10.2 22.9 0.74 9.9 22.9 1.1 1 0 0 1 1 1 0 LicD family HGTP_anticodon2 PF12745.7 EGO56254.1 - 0.62 9.5 21.0 0.79 9.2 21.0 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Membralin PF09746.9 EGO56254.1 - 0.72 8.8 10.3 0.75 8.8 10.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein Hid1 PF12722.7 EGO56254.1 - 0.94 7.5 11.6 0.96 7.5 11.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-3_zeta PF05091.12 EGO56254.1 - 0.99 8.3 21.1 1 8.2 21.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 EGO56254.1 - 1.1 8.9 18.4 1.5 8.4 18.4 1.2 1 0 0 1 1 1 0 Spt20 family SAPS PF04499.15 EGO56254.1 - 1.1 8.0 12.9 1.3 7.7 12.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein XRN_M PF17846.1 EGO56254.1 - 1.1 8.1 16.2 1.3 7.9 16.2 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Neur_chan_memb PF02932.16 EGO56254.1 - 1.1 9.2 14.6 1.3 9.0 14.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Kei1 PF08552.11 EGO56254.1 - 1.2 9.0 4.6 1.5 8.7 4.6 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF936 PF06075.12 EGO56254.1 - 1.3 7.9 25.1 1.4 7.8 25.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) ALMT PF11744.8 EGO56254.1 - 1.3 7.8 14.6 1.4 7.7 14.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 EGO56254.1 - 1.3 6.8 18.0 1.5 6.7 18.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4569 PF15133.6 EGO56254.1 - 1.3 8.6 15.2 1.6 8.4 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) NPR3 PF03666.13 EGO56254.1 - 1.4 7.6 28.6 1.6 7.4 28.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 EGO56254.1 - 1.4 8.6 27.6 9.3 5.9 27.6 1.9 1 1 0 1 1 1 0 Connexin DUF262 PF03235.14 EGO56254.1 - 1.5 8.9 13.7 1.8 8.7 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 MDFI PF15316.6 EGO56254.1 - 1.8 8.7 11.9 2.2 8.4 11.9 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Gti1_Pac2 PF09729.9 EGO56254.1 - 2.4 8.2 23.6 3.1 7.8 23.6 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family MDM10 PF12519.8 EGO56254.1 - 3.1 6.5 17.9 3.4 6.4 17.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CSG2 PF16965.5 EGO56254.1 - 3.1 6.6 6.6 3.4 6.5 6.6 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Paramyxo_ncap PF00973.19 EGO56254.1 - 4 6.2 16.0 5 5.9 16.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SID-1_RNA_chan PF13965.6 EGO56254.1 - 5 5.4 5.8 5.3 5.3 5.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HCO3_cotransp PF00955.21 EGO56254.1 - 5.3 5.7 4.4 5.7 5.6 4.4 1.1 1 0 0 1 1 1 0 HCO3- transporter family HSF_DNA-bind PF00447.17 EGO56258.1 - 6.7e-19 68.3 1.4 1.8e-17 63.7 0.5 2.4 1 1 1 2 2 2 1 HSF-type DNA-binding Col_cuticle_N PF01484.17 EGO56258.1 - 0.17 12.0 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Mcl1_mid PF12341.8 EGO56261.1 - 6.3e-97 324.5 0.0 3.5e-96 322.0 0.0 2.2 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EGO56261.1 - 8.7e-23 80.2 0.5 4.1e-08 33.8 0.1 7.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO56261.1 - 4.8e-16 58.8 0.0 1.1e-05 25.6 0.0 7.1 2 1 6 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGO56261.1 - 8.5e-06 25.1 0.0 1.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region Gmad1 PF10647.9 EGO56261.1 - 5e-05 23.2 0.1 0.61 9.8 0.1 3.4 2 1 1 3 3 3 2 Lipoprotein LpqB beta-propeller domain eIF2A PF08662.11 EGO56261.1 - 0.00046 20.1 0.0 0.017 15.0 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EGO56261.1 - 0.082 12.9 0.1 27 4.8 0.0 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DNA_pol_alpha_N PF12254.8 EGO56261.1 - 0.093 12.8 4.8 0.28 11.3 4.8 1.8 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal MMS1_N PF10433.9 EGO56261.1 - 0.11 11.1 0.0 0.31 9.6 0.0 1.8 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term SWIRM-assoc_2 PF16496.5 EGO56261.1 - 4.5 6.0 5.6 20 3.9 3.4 2.1 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal WD40 PF00400.32 EGO56262.1 - 4.6e-11 43.1 18.1 0.052 14.5 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Sigma70_r1_2 PF00140.20 EGO56262.1 - 0.03 14.3 0.8 0.061 13.3 0.8 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 DUF627 PF04781.12 EGO56262.1 - 0.05 13.6 0.0 0.08 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Nup160 PF11715.8 EGO56262.1 - 0.068 11.8 0.2 30 3.1 0.0 3.2 2 2 1 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EGO56262.1 - 0.085 13.4 1.0 1.5 9.4 0.1 3.3 3 0 0 3 3 3 0 PQQ-like domain Nramp PF01566.18 EGO56266.1 - 2.3e-68 230.8 17.1 2.3e-68 230.8 17.1 2.2 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein DUF2427 PF10348.9 EGO56266.1 - 8 6.3 8.9 1.3 8.8 1.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) Na_Ca_ex PF01699.24 EGO56267.1 - 1e-33 116.4 38.8 7.7e-17 61.6 17.4 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein TMEM208_SND2 PF05620.11 EGO56267.1 - 0.0013 18.6 2.9 0.2 11.4 0.0 2.6 2 0 0 2 2 2 2 SRP-independent targeting protein 2/TMEM208 DUF2457 PF10446.9 EGO56267.1 - 0.0053 16.0 9.7 0.0072 15.5 9.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CDC45 PF02724.14 EGO56267.1 - 0.0056 15.0 0.2 0.0073 14.7 0.2 1.1 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 EGO56267.1 - 0.015 15.4 3.3 0.022 14.9 3.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein FAM176 PF14851.6 EGO56267.1 - 0.062 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 FAM176 family PGK PF00162.19 EGO56267.1 - 0.11 11.4 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase AF-4 PF05110.13 EGO56267.1 - 0.3 9.1 8.2 0.39 8.7 8.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GP67 PF17634.2 EGO56267.1 - 1.9 8.9 11.6 3.8 8.0 11.6 1.4 1 0 0 1 1 1 0 Gene product 67 Nop14 PF04147.12 EGO56267.1 - 2.3 6.3 7.0 3.1 5.9 7.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1180 PF06679.12 EGO56268.1 - 1.1 9.6 3.6 1.2 9.5 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) RCDG1 PF15725.5 EGO56268.1 - 6.2 7.3 10.5 6 7.4 9.9 1.3 1 1 0 1 1 1 0 Renal cancer differentiation gene 1 protein PAM2 PF07145.15 EGO56270.1 - 0.095 12.4 0.2 0.095 12.4 0.2 4.7 4 1 1 5 5 5 0 Ataxin-2 C-terminal region RabGAP-TBC PF00566.18 EGO56273.1 - 4.7e-50 170.2 0.5 9.5e-49 166.0 0.1 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Jnk-SapK_ap_N PF09744.9 EGO56273.1 - 0.0016 18.7 18.3 0.0016 18.7 18.3 3.9 3 1 1 4 4 4 1 JNK_SAPK-associated protein-1 Cnn_1N PF07989.11 EGO56273.1 - 0.02 15.1 21.6 0.091 12.9 6.1 3.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 KASH_CCD PF14662.6 EGO56273.1 - 0.024 14.5 28.7 0.16 11.8 9.7 2.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 EGO56273.1 - 0.08 13.2 22.1 0.2 11.9 0.2 4.3 5 0 0 5 5 5 0 Homeobox associated leucine zipper DUF4060 PF13269.6 EGO56273.1 - 0.15 12.2 0.1 0.41 10.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4060) Mod_r PF07200.13 EGO56273.1 - 0.46 10.6 22.8 0.99 9.5 9.6 3.3 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein FlaC_arch PF05377.11 EGO56273.1 - 6.9 7.1 10.2 4.9 7.6 2.7 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 EGO56273.1 - 7.5 6.6 12.4 2.9 8.0 2.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_S8e PF01201.22 EGO56274.1 - 1.8e-56 190.1 0.8 2.1e-56 189.9 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e An_peroxidase PF03098.15 EGO56274.1 - 0.062 11.9 0.1 0.092 11.3 0.1 1.2 1 0 0 1 1 1 0 Animal haem peroxidase DUF913 PF06025.12 EGO56275.1 - 8.9e-121 403.3 0.0 8.9e-121 403.3 0.0 6.7 6 2 0 6 6 6 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 EGO56275.1 - 7.8e-118 394.0 0.1 7.8e-118 394.0 0.1 4.7 5 0 0 5 5 5 1 Domain of Unknown Function (DUF908) HECT PF00632.25 EGO56275.1 - 7.5e-94 314.7 0.0 1.5e-93 313.6 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 EGO56275.1 - 7.8e-24 82.3 17.8 5.7e-08 32.0 3.0 3.9 3 0 0 3 3 3 3 Ubiquitin binding region Ribosomal_S6e PF01092.19 EGO56277.1 - 9.3e-60 200.1 0.0 1.9e-59 199.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Diphthamide_syn PF01866.17 EGO56278.1 - 8.3e-117 390.0 0.0 1e-116 389.6 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DPM3 PF08285.11 EGO56279.1 - 0.076 13.2 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF866 PF05907.13 EGO56280.1 - 8.7e-68 227.1 0.7 9.7e-68 227.0 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) HalOD2 PF18547.1 EGO56280.1 - 0.083 12.8 0.4 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 Halobacterial output domain 2 Zn_ribbon_SprT PF17283.2 EGO56280.1 - 0.094 12.6 2.3 4.2 7.3 0.0 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DUF4379 PF14311.6 EGO56280.1 - 4.7 7.6 7.7 0.22 11.9 1.3 2.1 2 1 1 3 3 3 0 Probable Zinc-ribbon domain Rpr2 PF04032.16 EGO56281.1 - 2.4e-15 56.6 0.6 2.4e-15 56.6 0.6 1.8 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.6 EGO56281.1 - 0.049 13.6 1.7 0.94 9.4 0.2 2.4 2 0 0 2 2 2 0 Nudix N-terminal Troponin-I_N PF11636.8 EGO56281.1 - 0.085 12.8 0.6 0.085 12.8 0.6 2.3 3 0 0 3 3 3 0 Troponin I residues 1-32 zf-ZPR1 PF03367.13 EGO56282.1 - 1.1e-113 376.3 0.1 9.4e-57 191.3 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Cytochrome_C7 PF14522.6 EGO56282.1 - 0.2 11.7 1.8 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c zinc-ribbons_6 PF07191.12 EGO56282.1 - 1.2 9.2 4.8 1.5 8.8 0.6 2.4 2 1 0 2 2 2 0 zinc-ribbons tRNA_int_end_N2 PF12928.7 EGO56284.1 - 5.8e-20 71.3 0.5 9.5e-20 70.6 0.5 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EGO56284.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Arrestin_C PF02752.22 EGO56285.1 - 5.2e-17 62.6 0.0 1e-15 58.4 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.21 EGO56287.1 - 5.9e-45 153.4 0.0 6.8e-45 153.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GGDEF PF00990.21 EGO56287.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain HSF_DNA-bind PF00447.17 EGO56288.1 - 4.9e-28 97.6 0.3 1.1e-27 96.4 0.3 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding RIH_assoc PF08454.11 EGO56288.1 - 0.015 15.1 5.1 0.03 14.2 5.1 1.4 1 0 0 1 1 1 0 RyR and IP3R Homology associated Ets PF00178.22 EGO56288.1 - 0.093 13.2 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Ets-domain Nup54 PF13874.6 EGO56288.1 - 0.16 12.0 5.2 0.14 12.2 2.1 2.4 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 Pro_isomerase PF00160.21 EGO56290.1 - 8e-44 149.7 0.0 1.6e-43 148.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP-synt_ab PF00006.25 EGO56291.1 - 8.7e-66 221.6 0.0 1.2e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGO56291.1 - 4.3e-14 52.8 0.8 8.6e-14 51.8 0.8 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Aldose_epim PF01263.20 EGO56292.1 - 1.3e-40 139.6 0.0 3.1e-40 138.4 0.0 1.5 1 1 0 1 1 1 1 Aldose 1-epimerase RRM_1 PF00076.22 EGO56294.1 - 8.9e-14 51.1 0.0 2.1e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGO56294.1 - 0.0027 17.3 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGO56294.1 - 0.056 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GRAB PF10375.9 EGO56295.1 - 8.4e-09 35.0 0.0 1.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain RBD-FIP PF09457.10 EGO56295.1 - 0.0019 18.1 2.6 0.0077 16.1 2.6 2.1 1 0 0 1 1 1 1 FIP domain Tup_N PF08581.10 EGO56295.1 - 0.0023 18.2 2.2 0.0023 18.2 2.2 4.6 3 2 2 5 5 4 1 Tup N-terminal Filament PF00038.21 EGO56295.1 - 0.026 14.1 59.5 0.11 12.0 33.2 2.2 1 1 1 2 2 2 0 Intermediate filament protein MTHFR PF02219.17 EGO56295.1 - 0.057 12.7 0.4 0.094 12.0 0.4 1.3 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase Golgin_A5 PF09787.9 EGO56295.1 - 0.057 12.9 62.9 1.2 8.5 20.9 3.0 1 1 2 3 3 3 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 EGO56295.1 - 0.07 13.3 32.7 0.078 13.2 13.6 3.4 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 EGO56295.1 - 0.16 10.8 63.3 0.18 10.7 24.3 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein CALCOCO1 PF07888.11 EGO56295.1 - 0.53 9.1 68.7 1.4 7.7 27.2 2.9 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Baculo_PEP_C PF04513.12 EGO56295.1 - 0.54 10.3 13.8 0.34 11.0 3.2 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 EGO56295.1 - 1.5 8.1 62.4 0.19 11.1 13.1 3.3 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 EGO56295.1 - 1.8 8.7 71.1 0.038 14.0 13.8 4.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 EGO56295.1 - 2.5 7.6 39.4 8 5.9 19.5 2.7 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF1664 PF07889.12 EGO56295.1 - 5.1 7.2 29.8 4.7 7.3 0.5 4.3 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) CHD5 PF04420.14 EGO56297.1 - 4.9e-65 218.2 3.0 4.9e-65 218.2 3.0 1.4 2 0 0 2 2 2 1 CHD5-like protein PV-1 PF06637.11 EGO56297.1 - 0.0091 14.9 0.3 0.012 14.4 0.3 1.2 1 0 0 1 1 1 1 PV-1 protein (PLVAP) PcfJ PF14284.6 EGO56297.1 - 1.1 9.1 3.1 0.29 11.0 0.2 1.4 2 0 0 2 2 2 0 PcfJ-like protein PPTA PF01239.22 EGO56298.1 - 3.9e-06 26.4 8.5 0.00085 19.0 0.6 3.9 4 0 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat Asp PF00026.23 EGO56300.1 - 9.5e-67 225.6 2.4 1.2e-66 225.3 2.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO56300.1 - 4.6e-09 36.8 8.1 1.4e-08 35.2 1.3 3.0 2 2 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO56300.1 - 0.65 10.7 3.8 2.1 9.0 0.1 3.4 3 1 0 3 3 3 0 Aspartyl protease Aa_trans PF01490.18 EGO56301.1 - 2.8e-74 250.3 22.4 3.5e-74 250.0 22.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NTP_transf_2 PF01909.23 EGO56302.1 - 0.035 14.4 0.0 0.036 14.3 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase domain Ras PF00071.22 EGO56303.1 - 3.5e-56 189.3 0.0 4e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO56303.1 - 2.5e-21 76.1 0.0 3.5e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO56303.1 - 1.3e-07 31.2 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGO56303.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGO56303.1 - 0.15 11.4 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region KOW PF00467.29 EGO56304.1 - 3.9e-05 23.4 0.1 0.0001 22.1 0.1 1.7 1 0 0 1 1 1 1 KOW motif YajC PF02699.15 EGO56304.1 - 0.046 13.6 0.1 0.18 11.7 0.1 2.0 1 0 0 1 1 1 0 Preprotein translocase subunit IKI3 PF04762.12 EGO56305.1 - 0 1076.4 0.0 0 1076.1 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 EGO56305.1 - 0.0011 19.2 0.4 1.4 9.2 0.0 4.7 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 EGO56305.1 - 0.021 14.7 0.3 0.065 13.1 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGO56305.1 - 0.96 9.7 4.1 0.46 10.7 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3984 PF13136.6 EGO56306.1 - 2.3e-92 309.9 14.4 2.3e-92 309.9 14.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3984) DUF3134 PF11332.8 EGO56306.1 - 0.092 13.1 0.1 0.092 13.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3134) PAC1 PF16094.5 EGO56306.1 - 0.37 9.9 1.5 0.78 8.8 0.4 1.9 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 Hpt PF01627.23 EGO56307.1 - 3.8e-11 43.1 0.0 5.6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Hpt domain AKAP7_NLS PF10469.9 EGO56308.1 - 2.4e-24 86.4 0.0 1.5e-23 83.8 0.0 2.1 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 EGO56308.1 - 0.05 13.5 0.1 0.082 12.8 0.1 1.5 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily Tropomyosin_1 PF12718.7 EGO56309.1 - 0.0037 17.4 1.1 0.0037 17.4 1.1 2.4 3 0 0 3 3 3 1 Tropomyosin like TPR_MLP1_2 PF07926.12 EGO56309.1 - 0.0059 16.7 4.7 0.0059 16.7 4.7 2.1 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 EGO56309.1 - 0.014 15.6 1.6 0.034 14.3 1.6 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PKcGMP_CC PF16808.5 EGO56309.1 - 0.057 13.3 5.5 2 8.3 1.7 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Atg14 PF10186.9 EGO56309.1 - 0.063 12.4 3.8 0.024 13.7 1.0 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lectin_N PF03954.14 EGO56309.1 - 0.3 10.8 4.0 21 4.8 0.4 3.2 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain Golgin_A5 PF09787.9 EGO56309.1 - 0.44 10.0 7.2 0.047 13.1 2.9 1.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 Spc7 PF08317.11 EGO56309.1 - 0.47 9.3 8.4 0.059 12.2 3.9 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 EGO56309.1 - 0.52 10.3 3.4 17 5.5 1.0 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.6 EGO56309.1 - 0.94 9.1 11.8 0.087 12.5 7.3 1.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease OmpH PF03938.14 EGO56309.1 - 1.5 9.2 4.7 4.2 7.7 0.6 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) EzrA PF06160.12 EGO56309.1 - 2.8 6.0 7.2 0.24 9.6 2.6 1.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA APG6_N PF17675.1 EGO56309.1 - 5.2 7.6 8.7 1 9.9 5.0 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Sugar_tr PF00083.24 EGO56313.1 - 4.1e-96 322.6 21.3 5e-96 322.3 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO56313.1 - 7.4e-21 74.4 49.9 1.7e-19 70.0 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Stc1 PF12898.7 EGO56315.1 - 3.3e-16 59.6 6.4 6.1e-16 58.7 6.4 1.5 1 0 0 1 1 1 1 Stc1 domain Pkinase PF00069.25 EGO56316.1 - 6e-56 189.7 0.0 9.1e-56 189.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO56316.1 - 6.8e-32 110.8 0.0 2.3e-30 105.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO56316.1 - 0.0028 16.7 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EGO56316.1 - 0.04 12.9 0.0 0.056 12.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HSP70 PF00012.20 EGO56317.1 - 4.5e-12 45.0 0.3 3.1e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein FtsA PF14450.6 EGO56317.1 - 0.0084 16.5 0.8 0.035 14.5 0.0 2.3 2 2 0 2 2 2 1 Cell division protein FtsA CPT PF07931.12 EGO56318.1 - 0.0011 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 EGO56318.1 - 0.0027 18.3 0.0 0.014 16.0 0.0 2.2 3 0 0 3 3 3 1 AAA domain PRK PF00485.18 EGO56318.1 - 0.0076 16.0 0.0 0.021 14.6 0.0 1.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 EGO56318.1 - 0.023 15.0 0.5 0.059 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain PTH2 PF01981.16 EGO56319.1 - 1.6e-46 157.4 0.2 2.3e-46 156.9 0.2 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF5526 PF17664.1 EGO56319.1 - 0.015 14.9 1.1 0.025 14.1 0.0 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5526) Hom_end PF05204.14 EGO56319.1 - 0.071 13.3 0.5 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 Homing endonuclease DUF4535 PF15054.6 EGO56319.1 - 0.19 11.5 0.5 0.61 9.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) BING4CT PF08149.11 EGO56320.1 - 2.6e-40 136.1 0.0 8.8e-36 121.6 0.0 3.3 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 EGO56320.1 - 2.4e-08 34.2 0.1 3.1 8.2 0.0 5.8 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO56320.1 - 8.6e-05 23.2 0.0 0.11 13.5 0.0 4.3 3 1 0 3 3 3 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EGO56320.1 - 0.01 14.4 0.0 2.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 EGO56320.1 - 0.012 14.6 0.0 0.032 13.3 0.0 1.5 1 1 0 1 1 1 0 Coatomer WD associated region RIBIOP_C PF04950.12 EGO56321.1 - 1.1e-108 363.1 0.0 2.1e-108 362.2 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EGO56321.1 - 1e-15 57.5 0.1 1.6e-14 53.7 0.1 2.6 1 1 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 EGO56321.1 - 0.11 12.0 0.1 0.45 10.0 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Calcipressin PF04847.12 EGO56322.1 - 7.1e-78 260.6 0.0 8.8e-78 260.3 0.0 1.1 1 0 0 1 1 1 1 Calcipressin DUF2236 PF09995.9 EGO56323.1 - 3.2e-33 115.8 0.3 6.7e-33 114.8 0.1 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Neugrin PF06413.11 EGO56324.1 - 2.6e-12 47.2 1.0 2.6e-12 47.2 1.0 2.3 1 1 2 3 3 3 1 Neugrin MRP-L20 PF12824.7 EGO56324.1 - 0.00065 19.9 9.4 0.00065 19.9 9.4 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Endonuc_Holl PF10107.9 EGO56324.1 - 3.8 7.3 12.2 2.7 7.8 3.9 2.3 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase TFIIA PF03153.13 EGO56326.1 - 1.4 8.8 24.1 0.11 12.4 7.1 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit C2 PF00168.30 EGO56327.1 - 3.1e-28 98.1 0.0 2.2e-16 60.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain tRNA-synt_2d PF01409.20 EGO56328.1 - 4.9e-46 157.2 0.3 1.4e-23 83.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EGO56328.1 - 2.2e-27 95.3 0.0 4.7e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.27 EGO56329.1 - 2.6e-57 190.8 1.5 1.1e-19 70.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGO56329.1 - 0.078 12.1 0.7 1.7 7.8 0.1 2.6 2 1 1 3 3 3 0 Gammaproteobacterial serine protease Tim17 PF02466.19 EGO56329.1 - 0.11 12.9 0.4 0.26 11.7 0.4 1.7 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family RNA_pol_A_bac PF01000.26 EGO56330.1 - 2e-33 115.1 0.0 3.1e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGO56330.1 - 5e-18 64.3 0.0 6.5e-18 63.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GrpE PF01025.19 EGO56331.1 - 1e-49 168.4 6.3 1.3e-49 168.1 6.3 1.1 1 0 0 1 1 1 1 GrpE Med21 PF11221.8 EGO56331.1 - 0.025 14.9 2.0 0.056 13.7 2.0 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF3597 PF12200.8 EGO56331.1 - 0.14 12.7 1.9 0.33 11.5 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Torus PF16131.5 EGO56332.1 - 0.021 15.5 0.1 0.022 15.5 0.1 1.1 1 0 0 1 1 1 0 Torus domain Sfi1 PF08457.10 EGO56332.1 - 0.033 12.7 0.1 0.035 12.7 0.1 1.0 1 0 0 1 1 1 0 Sfi1 spindle body protein Glyco_hydro_15 PF00723.21 EGO56333.1 - 3.2e-107 359.1 0.7 3.8e-107 358.8 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EGO56333.1 - 2.4e-33 113.9 0.5 5.4e-33 112.8 0.5 1.7 1 0 0 1 1 1 1 Starch binding domain SART-1 PF03343.13 EGO56334.1 - 1.5e-173 578.8 67.1 1.5e-173 578.8 67.1 1.5 2 0 0 2 2 2 1 SART-1 family DJ-1_PfpI PF01965.24 EGO56336.1 - 1.3e-16 60.9 0.0 3.8e-16 59.3 0.0 1.7 2 0 0 2 2 2 1 DJ-1/PfpI family Chromo PF00385.24 EGO56337.1 - 4e-13 49.0 2.3 1.2e-12 47.5 2.3 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ras PF00071.22 EGO56339.1 - 5.7e-63 211.4 0.3 6.7e-63 211.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO56339.1 - 1.7e-35 121.8 0.2 2.4e-35 121.3 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO56339.1 - 8.4e-13 48.1 0.1 1.1e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGO56339.1 - 2.1e-07 31.0 0.1 3.2e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO56339.1 - 1.2e-05 25.0 0.2 6.8e-05 22.5 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGO56339.1 - 0.00019 21.3 0.2 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 EGO56339.1 - 0.0012 18.3 0.1 0.0017 17.7 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EGO56339.1 - 0.0028 17.9 0.0 0.028 14.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 EGO56339.1 - 0.017 14.6 0.0 0.036 13.5 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EGO56339.1 - 0.022 15.1 0.0 0.032 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EGO56339.1 - 0.027 15.0 0.2 0.036 14.6 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 EGO56339.1 - 0.041 13.9 0.2 0.19 11.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 EGO56339.1 - 0.042 13.6 0.1 0.089 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EGO56339.1 - 0.055 13.0 0.1 0.12 11.8 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 EGO56339.1 - 0.067 12.6 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 EGO56339.1 - 0.084 12.0 0.0 0.23 10.5 0.0 1.7 1 1 0 2 2 2 0 MCM P-loop domain AAA_7 PF12775.7 EGO56339.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Brix PF04427.18 EGO56340.1 - 2.2e-40 138.9 0.0 3.2e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain RGS12_us1 PF16613.5 EGO56340.1 - 1.2 9.5 4.7 0.32 11.3 0.2 2.1 2 0 0 2 2 2 0 Unstructured region of RGS12 Arb2 PF09757.9 EGO56341.1 - 6.5e-105 349.9 0.2 9.4e-105 349.4 0.2 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 EGO56341.1 - 1.9e-79 267.4 0.0 2.8e-79 266.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Gp_dh_C PF02800.20 EGO56343.1 - 1.9e-71 238.8 0.1 2.7e-71 238.3 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EGO56343.1 - 6.9e-39 132.3 0.1 1.3e-38 131.3 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EGO56343.1 - 0.0087 16.2 0.1 0.032 14.4 0.1 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 EGO56343.1 - 0.015 15.2 0.1 0.036 14.0 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGO56343.1 - 0.068 12.5 0.1 0.85 8.9 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PAPA-1 PF04795.12 EGO56349.1 - 3.1e-30 104.8 3.2 3.1e-30 104.8 3.2 4.3 2 1 1 3 3 3 1 PAPA-1-like conserved region BSP_II PF05432.11 EGO56349.1 - 5.5 6.6 63.3 0.07 12.8 38.3 2.4 1 1 2 3 3 3 0 Bone sialoprotein II (BSP-II) Headcase PF16002.5 EGO56350.1 - 0.088 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Headcase protein Pex14_N PF04695.13 EGO56351.1 - 3.2e-33 115.6 0.9 3.2e-33 115.6 0.9 3.2 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region ATG16 PF08614.11 EGO56351.1 - 0.043 14.0 0.1 0.043 14.0 0.1 2.8 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) PI3K_P85_iSH2 PF16454.5 EGO56351.1 - 0.051 13.2 1.1 0.26 10.9 0.1 2.5 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain MerR-DNA-bind PF09278.11 EGO56351.1 - 0.71 10.4 3.2 2.2 8.9 1.1 2.6 2 0 0 2 2 2 0 MerR, DNA binding CSRNP_N PF16019.5 EGO56351.1 - 5.3 6.9 7.3 4 7.3 2.1 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DUF4050 PF13259.6 EGO56352.1 - 2.7e-58 197.3 0.8 2.7e-58 197.3 0.8 4.4 3 1 0 3 3 3 1 Protein of unknown function (DUF4050) Vps39_1 PF10366.9 EGO56353.1 - 2.1e-34 118.1 0.1 2.1e-32 111.6 0.0 3.6 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 EGO56353.1 - 1.6e-25 89.6 0.0 5.4e-25 88.0 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 EGO56353.1 - 7.3e-18 65.1 0.0 1.5e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 EGO56353.1 - 2.4e-05 24.3 2.2 0.00011 22.1 0.4 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.28 EGO56353.1 - 0.0014 18.4 2.0 1.3 9.0 0.7 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGO56353.1 - 0.017 15.2 0.6 43 4.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGO56353.1 - 0.08 13.5 0.0 11 6.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGO56353.1 - 0.11 12.5 0.0 24 4.9 0.0 2.6 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 EGO56353.1 - 0.17 12.2 1.0 70 3.8 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGO56353.1 - 0.29 11.4 2.9 19 5.8 1.0 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Bacillus_HBL PF05791.11 EGO56353.1 - 0.33 10.8 1.1 4.5 7.1 0.5 2.4 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) SPX PF03105.19 EGO56354.1 - 9.9e-49 167.3 1.7 7.4e-36 124.9 0.3 2.1 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 EGO56354.1 - 5.4e-35 121.3 35.0 8.3e-35 120.7 35.0 1.3 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EGO56354.1 - 5.3e-26 91.5 32.7 5.3e-26 91.5 32.7 2.2 2 1 0 2 2 2 1 Citrate transporter ATPase_gene1 PF09527.10 EGO56354.1 - 0.014 15.6 2.7 0.014 15.6 2.7 3.2 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Gon7 PF08738.10 EGO56355.1 - 2.5e-14 53.3 14.8 5.4e-13 49.0 14.8 2.0 1 1 0 1 1 1 1 Gon7 family UCMA PF17085.5 EGO56355.1 - 0.0021 18.1 1.5 0.0026 17.8 1.5 1.2 1 0 0 1 1 1 1 Unique cartilage matrix associated protein SSP160 PF06933.11 EGO56355.1 - 8.6 4.4 13.5 9.1 4.3 13.5 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HbrB PF08539.11 EGO56356.1 - 3.1e-53 180.2 0.0 3.1e-53 180.2 0.0 2.3 3 0 0 3 3 3 1 HbrB-like Spt20 PF12090.8 EGO56356.1 - 4.4 6.9 22.9 11 5.5 22.9 1.6 1 0 0 1 1 1 0 Spt20 family LIM_bind PF01803.16 EGO56359.1 - 4.8e-73 245.6 0.0 4.8e-73 245.6 0.0 4.9 4 2 1 5 5 5 1 LIM-domain binding protein Atg8 PF02991.16 EGO56360.1 - 2.9e-51 172.0 0.2 3.4e-51 171.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EGO56360.1 - 3.3e-06 27.4 0.0 3.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.18 EGO56361.1 - 2.5e-142 472.9 0.1 3e-142 472.7 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Nop14 PF04147.12 EGO56362.1 - 0.56 8.4 13.0 0.92 7.6 13.0 1.2 1 0 0 1 1 1 0 Nop14-like family SWIM PF04434.17 EGO56362.1 - 1.1 9.0 4.7 2.2 8.0 0.1 2.3 2 0 0 2 2 2 0 SWIM zinc finger CDC45 PF02724.14 EGO56362.1 - 2.1 6.6 9.4 3.5 5.8 9.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Cytomega_UL84 PF06284.11 EGO56362.1 - 4.1 5.8 7.5 8.3 4.7 7.5 1.4 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein OAD_gamma PF04277.13 EGO56362.1 - 6.6 7.4 6.5 17 6.1 1.0 2.8 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Rxt3 PF08642.10 EGO56362.1 - 7.6 7.3 6.2 3.4 8.5 1.4 2.4 1 1 1 2 2 2 0 Histone deacetylation protein Rxt3 Cwf_Cwc_15 PF04889.12 EGO56362.1 - 8 6.1 19.0 1 9.1 13.9 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MitMem_reg PF13012.6 EGO56363.1 - 5e-38 130.0 0.1 9.7e-38 129.0 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGO56363.1 - 3.5e-32 110.9 0.0 7.7e-32 109.8 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 EGO56363.1 - 0.16 11.6 4.2 0.25 11.0 4.2 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain Connexin PF00029.19 EGO56363.1 - 0.81 9.4 2.1 1.3 8.7 2.1 1.3 1 0 0 1 1 1 0 Connexin Inhibitor_I9 PF05922.16 EGO56364.1 - 0.001 19.7 0.4 0.0015 19.2 0.4 1.3 1 1 0 1 1 1 1 Peptidase inhibitor I9 ADK PF00406.22 EGO56365.1 - 3.8e-59 199.1 0.0 4.9e-59 198.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGO56365.1 - 1.8e-23 83.5 0.1 4.4e-23 82.2 0.0 1.7 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 EGO56365.1 - 1.7e-17 63.1 0.1 4.7e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EGO56365.1 - 2.7e-05 24.7 0.0 5.4e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGO56365.1 - 0.00019 21.6 0.0 0.00042 20.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 EGO56365.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Thymidylate_kin PF02223.17 EGO56365.1 - 0.11 12.2 0.1 0.32 10.6 0.1 1.7 2 0 0 2 2 2 0 Thymidylate kinase AAA_24 PF13479.6 EGO56365.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF5315 PF17242.2 EGO56366.1 - 4.3e-29 100.1 1.1 4.3e-29 100.1 1.1 1.8 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) Ribosom_S12_S23 PF00164.25 EGO56367.1 - 3.8e-51 171.5 0.6 4.7e-51 171.2 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UbiA PF01040.18 EGO56368.1 - 6.7e-41 140.2 18.6 8.6e-41 139.9 18.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family JmjC PF02373.22 EGO56369.1 - 7.6e-11 42.5 0.1 4.5e-10 40.0 0.1 2.3 2 1 0 2 2 2 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 EGO56369.1 - 1.4e-08 34.8 8.8 1.4e-08 34.8 8.8 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 EGO56369.1 - 0.062 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Cupin domain DUF4452 PF14618.6 EGO56374.1 - 3.3e-80 267.9 8.7 4.4e-80 267.5 8.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) BTB PF00651.31 EGO56375.1 - 0.00023 21.3 0.0 0.00055 20.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain TFIIA PF03153.13 EGO56375.1 - 0.057 13.4 24.2 0.11 12.5 24.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tim29 PF10171.9 EGO56375.1 - 0.072 12.6 0.5 0.13 11.7 0.5 1.3 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 Suf PF05843.14 EGO56375.1 - 2.3 8.1 15.7 4.6 7.1 15.7 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4820 PF16091.5 EGO56375.1 - 2.4 7.4 11.4 5.4 6.3 11.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PAT1 PF09770.9 EGO56375.1 - 2.6 6.2 19.4 3.4 5.8 19.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TauD PF02668.16 EGO56376.1 - 1e-54 186.1 0.1 1.2e-54 185.9 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cyclin_N PF00134.23 EGO56377.1 - 1.9e-11 43.8 0.1 5.5e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EGO56377.1 - 0.017 15.5 0.2 0.086 13.2 0.1 2.2 3 0 0 3 3 3 0 Cyclin C-terminal domain Turandot PF07240.11 EGO56377.1 - 0.14 12.1 0.2 0.26 11.3 0.2 1.4 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Mito_carr PF00153.27 EGO56378.1 - 1.5e-67 223.5 2.6 2.1e-24 85.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 EGO56378.1 - 3.2e-20 70.1 7.1 1.2e-05 24.5 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EGO56378.1 - 5.9e-18 65.1 6.1 8e-10 39.0 2.7 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGO56378.1 - 1.4e-16 58.9 6.4 4.3e-05 23.1 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EGO56378.1 - 7.5e-16 56.8 10.9 5.4e-05 22.5 1.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EGO56378.1 - 1.4e-12 47.2 5.8 0.0012 18.6 0.0 3.5 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGO56378.1 - 2.6e-06 27.7 0.2 1.7e-05 25.1 0.2 2.2 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGO56378.1 - 0.00099 19.0 3.0 0.37 10.8 0.3 3.2 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EGO56378.1 - 0.0084 16.0 0.2 2.7 7.9 0.0 2.9 3 0 0 3 3 3 1 EF hand GramPos_pilinD1 PF16555.5 EGO56378.1 - 0.016 15.4 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain EF-hand_9 PF14658.6 EGO56378.1 - 0.032 14.6 0.1 1.2 9.5 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain DUF4097 PF13349.6 EGO56380.1 - 0.00089 18.7 2.5 0.033 13.5 2.6 3.0 1 1 0 1 1 1 1 Putative adhesin IER PF05760.12 EGO56382.1 - 0.11 12.8 4.2 0.058 13.7 2.0 1.5 1 1 0 1 1 1 0 Immediate early response protein (IER) Mito_carr PF00153.27 EGO56383.1 - 1.6e-42 143.4 6.6 8.6e-15 54.4 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGO56383.1 - 0.0079 15.4 0.7 0.098 11.8 0.3 2.3 2 0 0 2 2 2 1 Gammaproteobacterial serine protease DUF3337 PF11816.8 EGO56384.1 - 1.3e-55 187.9 0.0 3.7e-55 186.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EGO56384.1 - 2.6e-22 78.7 8.6 0.00022 21.9 0.1 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 EGO56384.1 - 0.0012 17.6 1.4 0.019 13.6 0.1 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGO56384.1 - 0.0085 16.4 0.1 0.15 12.4 0.1 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO56384.1 - 0.011 14.7 0.2 0.12 11.3 0.0 2.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RNA_pol_Rpc4 PF05132.14 EGO56384.1 - 0.52 10.7 5.2 0.41 11.1 2.9 2.0 1 1 0 2 2 2 0 RNA polymerase III RPC4 ATP_bind_3 PF01171.20 EGO56385.1 - 3.8e-39 134.3 0.0 1.1e-26 93.7 0.0 2.3 2 0 0 2 2 2 2 PP-loop family Asn_synthase PF00733.21 EGO56385.1 - 0.019 14.7 0.1 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 Asparagine synthase PPTA PF01239.22 EGO56386.1 - 4.5e-36 121.5 10.6 2.4e-08 33.4 0.0 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF3682 PF12446.8 EGO56386.1 - 3.7 8.0 17.8 0.38 11.2 11.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) ANAPC4_WD40 PF12894.7 EGO56387.1 - 0.00027 21.2 0.2 0.032 14.5 0.1 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO56387.1 - 0.0048 17.7 7.0 0.01 16.7 0.0 4.4 6 0 0 6 6 6 1 WD domain, G-beta repeat p450 PF00067.22 EGO56388.1 - 3.9e-07 29.2 0.5 9e-07 28.0 0.5 1.5 1 0 0 1 1 1 1 Cytochrome P450 SNARE PF05739.19 EGO56390.1 - 2.7e-10 40.1 1.3 4.3e-10 39.4 0.1 2.0 2 0 0 2 2 2 1 SNARE domain WXG100 PF06013.12 EGO56390.1 - 0.0042 17.3 3.2 0.81 10.0 0.0 3.6 2 2 1 3 3 3 1 Proteins of 100 residues with WXG BAR_3 PF16746.5 EGO56390.1 - 0.056 13.2 1.1 0.14 11.8 0.1 1.9 2 0 0 2 2 2 0 BAR domain of APPL family Not3 PF04065.15 EGO56390.1 - 0.09 12.2 1.4 5.1 6.5 0.1 2.2 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Use1 PF09753.9 EGO56390.1 - 0.12 12.0 2.0 0.32 10.7 2.0 1.8 1 1 0 1 1 1 0 Membrane fusion protein Use1 HrpB7 PF09486.10 EGO56390.1 - 0.15 12.4 9.0 0.33 11.3 3.9 2.6 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Allexi_40kDa PF05549.11 EGO56390.1 - 1.5 8.2 5.6 0.6 9.6 2.5 1.8 2 0 0 2 2 2 0 Allexivirus 40kDa protein PilJ PF13675.6 EGO56390.1 - 1.7 8.7 7.3 0.22 11.5 1.2 2.4 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term FliJ PF02050.16 EGO56390.1 - 3.6 7.8 10.0 5.4 7.3 2.7 2.9 2 1 1 3 3 3 0 Flagellar FliJ protein FUSC-like PF12805.7 EGO56390.1 - 3.8 6.5 7.4 1.6 7.7 1.0 2.2 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS Fez1 PF06818.15 EGO56390.1 - 8 6.9 8.1 2.6e+02 1.9 8.0 2.2 1 1 0 1 1 1 0 Fez1 Atg14 PF10186.9 EGO56390.1 - 8 5.4 8.7 1.7 7.7 1.9 2.0 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3716 PF12511.8 EGO56391.1 - 1.7e-11 44.0 1.8 2.9e-11 43.2 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF3245 PF11595.8 EGO56391.1 - 1.1 9.7 5.2 2 8.9 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) MGC-24 PF05283.11 EGO56391.1 - 1.7 9.1 10.5 0.24 11.9 6.4 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Tfb4 PF03850.14 EGO56394.1 - 9.5e-86 287.7 0.6 8.1e-61 205.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor Tfb4 XRCC4 PF06632.12 EGO56395.1 - 3.7e-09 35.9 5.9 3.7e-09 35.9 5.9 2.5 1 1 2 3 3 3 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 FlxA PF14282.6 EGO56395.1 - 0.1 12.6 12.0 0.26 11.3 11.0 2.3 1 1 0 1 1 1 0 FlxA-like protein DUF1993 PF09351.10 EGO56395.1 - 0.17 12.0 0.7 0.35 11.0 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) AAA_13 PF13166.6 EGO56395.1 - 0.17 10.5 5.2 0.25 9.9 5.2 1.2 1 0 0 1 1 1 0 AAA domain SlyX PF04102.12 EGO56395.1 - 0.56 10.9 5.5 1.8 9.3 5.5 1.9 1 0 0 1 1 1 0 SlyX ACCA PF03255.14 EGO56395.1 - 0.81 9.6 5.9 0.98 9.3 2.6 2.3 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Atg14 PF10186.9 EGO56395.1 - 1.4 8.0 8.9 2.2 7.3 8.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EGO56395.1 - 7.5 5.3 13.0 12 4.6 13.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Cofilin_ADF PF00241.20 EGO56398.1 - 2e-37 127.7 0.5 2.3e-37 127.5 0.5 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cpn60_TCP1 PF00118.24 EGO56399.1 - 4.4e-86 289.5 9.9 2.1e-85 287.2 9.9 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1859 PF08948.10 EGO56399.1 - 0.13 12.2 0.3 0.38 10.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1859) HET PF06985.11 EGO56401.1 - 4e-35 121.3 2.0 2.5e-34 118.7 0.5 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 EGO56402.1 - 2.6e-31 108.9 0.8 4.4e-31 108.2 0.8 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Antimicrobial12 PF08107.11 EGO56403.1 - 0.038 13.7 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Pleurocidin family Sof1 PF04158.14 EGO56404.1 - 5.1e-31 106.8 17.8 9.6e-31 105.9 17.8 1.5 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EGO56404.1 - 3.8e-25 87.7 6.5 3.7e-06 27.6 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO56404.1 - 2.3e-06 27.8 0.9 0.055 13.8 0.0 4.3 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGO56404.1 - 5.6e-06 26.4 0.1 3 7.9 0.0 5.3 3 2 3 6 6 6 2 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 EGO56404.1 - 0.0012 18.7 1.9 0.0012 18.7 0.2 1.8 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EGO56404.1 - 0.015 13.8 0.1 0.041 12.4 0.1 1.7 1 1 0 1 1 1 0 Cytochrome D1 heme domain RPN6_N PF18055.1 EGO56405.1 - 7e-48 161.8 3.6 7.1e-48 161.8 0.3 2.6 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EGO56405.1 - 4.2e-21 75.4 0.8 1.4e-20 73.7 0.2 2.3 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 EGO56405.1 - 1.4e-11 43.9 1.0 3.3e-11 42.7 1.0 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 EGO56405.1 - 0.00018 21.2 0.2 0.00037 20.2 0.2 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_MalT PF17874.1 EGO56405.1 - 0.00021 20.8 1.7 0.00021 20.8 1.7 2.3 2 1 0 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 EGO56405.1 - 0.0083 16.4 22.4 0.35 11.2 3.0 5.7 5 1 0 6 6 5 2 Tetratricopeptide repeat DUF410 PF04190.13 EGO56405.1 - 0.014 15.2 1.0 0.049 13.4 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF410) TPR_7 PF13176.6 EGO56405.1 - 0.028 14.5 6.3 1.4 9.1 1.0 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat Med2 PF11214.8 EGO56405.1 - 0.032 14.4 0.3 0.28 11.3 0.1 2.6 2 0 0 2 2 2 0 Mediator complex subunit 2 HTH_Crp_2 PF13545.6 EGO56405.1 - 0.038 14.0 0.1 0.37 10.8 0.0 2.5 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DprA_WH PF17782.1 EGO56405.1 - 0.046 13.8 0.1 0.32 11.1 0.0 2.4 3 0 0 3 3 2 0 DprA winged helix domain TPR_10 PF13374.6 EGO56405.1 - 0.12 12.3 3.0 35 4.5 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF87 PF01935.17 EGO56405.1 - 0.18 11.9 1.6 0.68 10.0 0.2 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain TPR_21 PF09976.9 EGO56405.1 - 0.53 10.0 12.6 0.6 9.8 2.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 EGO56405.1 - 0.59 10.9 0.1 0.59 10.9 0.1 2.7 3 0 0 3 3 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGO56405.1 - 4.9 7.1 8.9 10 6.1 0.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGO56405.1 - 7.8 6.9 14.8 9.4 6.6 0.0 5.4 6 1 0 6 6 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGO56405.1 - 8.8 6.8 13.8 21 5.7 0.0 5.8 7 0 0 7 7 5 0 Tetratricopeptide repeat PCP_red PF08369.10 EGO56406.1 - 0.33 11.2 8.1 1 9.6 1.2 3.0 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Sds3 PF08598.11 EGO56408.1 - 1.6e-24 87.1 0.8 2.9e-24 86.3 0.8 1.6 1 1 0 1 1 1 1 Sds3-like DUF743 PF05332.11 EGO56408.1 - 0.5 10.4 2.1 2.4 8.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF743) LSM PF01423.22 EGO56409.1 - 3.6e-16 58.6 0.1 2.2e-15 56.1 0.0 1.9 2 0 0 2 2 2 1 LSM domain Hfq PF17209.3 EGO56409.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Mob1_phocein PF03637.17 EGO56412.1 - 5.2e-70 234.9 0.0 6.8e-70 234.5 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.18 EGO56413.1 - 6.6e-48 163.1 1.0 8.9e-48 162.7 1.0 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit ENT PF03735.14 EGO56413.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 ENT domain PMT PF02366.18 EGO56414.1 - 0.3 10.6 0.2 0.43 10.1 0.2 1.1 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase His_Phos_2 PF00328.22 EGO56415.1 - 0.00092 18.7 0.0 0.0083 15.5 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Carn_acyltransf PF00755.20 EGO56416.1 - 4.9e-214 712.3 0.0 3.7e-213 709.4 0.0 1.9 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase OB_NTP_bind PF07717.16 EGO56417.1 - 1.5e-23 83.0 0.1 1.5e-22 79.7 0.1 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EGO56417.1 - 1.6e-18 66.9 0.0 4.4e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGO56417.1 - 2.4e-11 44.0 0.0 8.1e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO56417.1 - 1.3e-08 34.8 0.1 3e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGO56417.1 - 1.8e-07 31.5 0.1 4.7e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EGO56417.1 - 0.00012 21.8 0.1 0.00038 20.1 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EGO56417.1 - 0.00029 20.6 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGO56417.1 - 0.0067 15.5 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 EGO56417.1 - 0.0086 16.1 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_23 PF13476.6 EGO56417.1 - 0.015 15.8 0.0 0.029 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EGO56417.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 EGO56417.1 - 0.028 14.8 0.5 0.32 11.4 0.1 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EGO56417.1 - 0.13 12.8 0.0 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Flavi_DEAD PF07652.14 EGO56417.1 - 0.17 11.9 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_7 PF12775.7 EGO56417.1 - 0.18 11.3 0.8 0.43 10.1 0.0 2.0 3 0 0 3 3 3 0 P-loop containing dynein motor region PRMT5_TIM PF17285.2 EGO56418.1 - 3.8e-83 278.6 0.0 5.1e-83 278.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 EGO56418.1 - 1.3e-66 223.7 0.0 2e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EGO56418.1 - 1.3e-60 204.3 0.3 2.5e-60 203.4 0.3 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain LSM PF01423.22 EGO56419.1 - 9.6e-21 73.3 0.2 1.1e-20 73.0 0.2 1.1 1 0 0 1 1 1 1 LSM domain RTP1_C1 PF10363.9 EGO56420.1 - 1.9e-22 79.6 0.5 5.2e-20 71.7 0.0 3.5 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EGO56420.1 - 5.1e-12 45.2 3.1 6.2e-12 45.0 1.1 2.2 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 2 PMC2NT PF08066.12 EGO56420.1 - 0.07 13.8 0.2 3.7 8.3 0.0 3.6 3 1 0 3 3 3 0 PMC2NT (NUC016) domain NKAIN PF05640.14 EGO56424.1 - 0.14 11.4 0.4 0.19 10.9 0.4 1.1 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein DEAD_2 PF06733.15 EGO56428.1 - 2.8e-57 193.2 0.4 6.1e-57 192.1 0.4 1.6 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 EGO56428.1 - 1.3e-47 162.0 0.8 5.9e-43 146.8 0.2 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EGO56428.1 - 4.4e-44 150.7 0.0 1.9e-43 148.6 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 EGO56428.1 - 1.6e-05 24.9 0.3 0.00054 20.0 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EGO56428.1 - 0.0014 17.4 0.0 0.011 14.5 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EGO56428.1 - 0.0062 16.3 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase PhoH PF02562.16 EGO56428.1 - 0.14 11.6 0.1 15 4.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein FTA4 PF13093.6 EGO56428.1 - 0.15 11.9 3.3 6.5 6.6 0.1 2.3 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 AAA_11 PF13086.6 EGO56428.1 - 1.8 8.2 6.8 0.77 9.5 0.1 2.6 2 1 0 2 2 2 0 AAA domain zf-C2H2 PF00096.26 EGO56431.1 - 8.7e-13 48.0 19.9 0.00026 21.3 0.7 3.9 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO56431.1 - 1.3e-09 38.0 16.5 0.00066 20.3 0.4 4.2 4 0 0 4 4 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGO56431.1 - 0.0079 16.6 1.9 0.0079 16.6 1.9 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 EGO56431.1 - 0.012 15.3 4.4 0.014 15.2 0.3 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 EGO56431.1 - 0.02 15.2 4.3 0.078 13.3 4.3 2.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 EGO56431.1 - 0.039 13.9 0.6 0.11 12.4 0.6 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 EGO56431.1 - 0.06 13.4 0.3 0.06 13.4 0.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EGO56431.1 - 0.41 11.0 4.6 0.74 10.2 3.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EGO56431.1 - 0.62 10.4 5.8 8.2 6.9 0.1 3.2 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 EGO56431.1 - 0.76 9.9 4.6 0.28 11.3 0.3 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger zf-TRAF PF02176.18 EGO56431.1 - 0.89 10.3 9.5 1.3 9.8 1.6 2.5 1 1 2 3 3 3 0 TRAF-type zinc finger zf-BED PF02892.15 EGO56431.1 - 1.4 9.0 9.9 0.61 10.2 5.5 2.4 2 0 0 2 2 2 0 BED zinc finger EPSP_synthase PF00275.20 EGO56434.1 - 6e-131 437.0 0.0 1.2e-130 436.0 0.0 1.5 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EGO56434.1 - 3.5e-102 341.1 0.0 6.3e-102 340.2 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EGO56434.1 - 3.4e-59 200.9 0.0 5.6e-59 200.2 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EGO56434.1 - 6.8e-39 133.5 0.0 3.5e-37 128.0 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EGO56434.1 - 4.2e-25 87.8 0.0 9.8e-25 86.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 EGO56434.1 - 8.3e-08 32.2 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 EGO56434.1 - 4.2e-07 30.1 0.0 2.2e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 EGO56434.1 - 1.5e-05 24.6 1.0 5e-05 23.0 1.0 2.0 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Zeta_toxin PF06414.12 EGO56434.1 - 0.038 13.3 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 EGO56434.1 - 0.063 13.8 0.0 0.31 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGO56434.1 - 0.1 13.0 0.5 0.89 9.9 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain AAA_24 PF13479.6 EGO56434.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.24 EGO56435.1 - 9.2e-130 433.5 20.5 1e-129 433.3 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO56435.1 - 5.6e-19 68.3 38.9 1.8e-13 50.2 16.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CENP-T_C PF15511.6 EGO56436.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EGO56436.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EGO56436.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGO56436.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EGO56436.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EGO56436.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGO56436.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EGO56436.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 EGO56436.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Histone PF00125.24 EGO56437.1 - 1.6e-51 174.1 2.5 1.8e-51 173.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EGO56437.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EGO56437.1 - 3.4e-05 24.5 1.0 3.9e-05 24.3 1.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EGO56437.1 - 3.6e-05 23.8 0.4 6.4e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EGO56437.1 - 0.0035 17.6 0.3 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGO56437.1 - 0.028 14.5 0.2 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGO56437.1 - 0.057 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DSBA PF01323.20 EGO56438.1 - 2e-19 70.1 0.0 2.3e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain PRP3 PF08572.10 EGO56439.1 - 5.4e-73 245.4 8.2 5.4e-73 245.4 8.2 1.6 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EGO56439.1 - 8.1e-49 165.5 1.0 8.1e-49 165.5 1.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.17 EGO56440.1 - 3.7e-86 288.8 0.0 6.2e-86 288.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGO56440.1 - 2.1e-68 229.8 0.3 4.2e-68 228.8 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGO56440.1 - 7.4e-32 110.5 0.0 1.9e-31 109.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EGO56440.1 - 5.5e-29 101.5 5.5 1.6e-28 100.0 1.3 3.5 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EGO56440.1 - 1.7e-18 66.5 7.4 2.4e-18 66.0 0.2 3.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 zf-C2H2 PF00096.26 EGO56442.1 - 1.3e-09 38.0 12.7 0.0087 16.5 1.2 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO56442.1 - 1.3e-05 25.6 8.7 0.27 12.2 1.0 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 EGO56442.1 - 2.2 8.6 6.9 0.43 10.9 1.3 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RasGAP PF00616.19 EGO56443.1 - 8.7e-33 113.8 0.2 1.8e-20 73.6 0.0 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 EGO56443.1 - 2.1e-06 27.9 0.2 6.5e-06 26.3 0.2 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HEAT PF02985.22 EGO56443.1 - 0.052 13.8 1.7 3.9 8.0 0.1 4.3 4 0 0 4 4 4 0 HEAT repeat XRN_N PF03159.18 EGO56444.1 - 2.6e-100 334.8 0.0 3.1e-100 334.6 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_3 PF13917.6 EGO56444.1 - 0.045 13.7 0.2 0.086 12.8 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 EGO56444.1 - 0.12 12.3 3.1 0.21 11.4 3.1 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4599 PF15371.6 EGO56444.1 - 0.12 12.9 0.4 0.24 12.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) Uso1_p115_head PF04869.14 EGO56445.1 - 1.4e-114 382.5 0.0 3.7e-114 381.1 0.0 1.8 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EGO56445.1 - 1.4e-19 70.7 38.0 1.4e-19 70.7 38.0 5.9 1 1 4 5 5 5 2 Uso1 / p115 like vesicle tethering protein, C terminal region HEAT PF02985.22 EGO56445.1 - 0.058 13.7 0.5 4.7 7.7 0.2 3.7 2 0 0 2 2 2 0 HEAT repeat DUF1664 PF07889.12 EGO56445.1 - 1.6 8.8 49.7 1.9 8.5 6.3 5.9 3 2 3 6 6 6 0 Protein of unknown function (DUF1664) WW PF00397.26 EGO56446.1 - 5.6e-10 39.1 8.2 1e-09 38.3 8.2 1.4 1 0 0 1 1 1 1 WW domain Choline_transpo PF04515.12 EGO56448.1 - 5.2e-26 91.6 20.6 5.2e-26 91.6 20.6 2.8 1 1 2 3 3 3 1 Plasma-membrane choline transporter Ras PF00071.22 EGO56449.1 - 8.1e-50 168.6 0.0 1.9e-38 131.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGO56449.1 - 1.1e-27 96.6 0.0 6.7e-18 65.0 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO56449.1 - 5.6e-12 45.5 0.0 6.8e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGO56449.1 - 6.7e-07 29.0 0.0 1.6e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGO56449.1 - 8.9e-06 25.2 0.0 4.3e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGO56449.1 - 0.00011 22.3 0.0 0.00097 19.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO56449.1 - 0.0038 17.2 0.1 0.85 9.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGO56449.1 - 0.037 14.3 0.1 0.92 9.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EGO56449.1 - 0.11 12.0 0.1 15 5.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGO56449.1 - 0.18 12.3 0.4 0.43 11.1 0.4 2.0 1 1 0 1 1 1 0 ABC transporter DUF3439 PF11921.8 EGO56449.1 - 0.23 11.4 4.9 0.41 10.6 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PMT PF02366.18 EGO56450.1 - 4e-85 285.3 19.5 4e-85 285.3 19.5 2.0 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EGO56450.1 - 1.2e-66 224.1 14.0 4e-66 222.4 14.0 1.9 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGO56450.1 - 1.3e-37 129.5 2.4 2e-37 128.9 2.4 1.2 1 0 0 1 1 1 1 MIR domain DUF3712 PF12505.8 EGO56451.1 - 4.2e-06 27.0 0.0 1.3e-05 25.4 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3712) L51_S25_CI-B8 PF05047.16 EGO56453.1 - 2.5e-25 88.1 0.1 4.3e-25 87.4 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MMR_HSR1 PF01926.23 EGO56454.1 - 3.7e-05 23.8 0.0 0.0009 19.3 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Phage_F PF02305.17 EGO56454.1 - 0.072 11.8 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Capsid protein (F protein) Cys_Met_Meta_PP PF01053.20 EGO56455.1 - 5.8e-141 469.5 0.0 6.6e-141 469.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGO56455.1 - 2.3e-09 36.7 0.2 3.9e-09 35.9 0.2 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGO56455.1 - 4.1e-09 36.2 0.1 9.5e-09 35.0 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EGO56455.1 - 3.8e-07 29.6 0.0 5.9e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 EGO56455.1 - 0.002 17.0 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 EGO56455.1 - 0.0042 15.7 0.1 0.006 15.2 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 EGO56455.1 - 0.0048 16.2 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase MARVEL PF01284.23 EGO56456.1 - 2.3e-13 50.4 14.8 3.4e-13 49.9 14.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain AMP-binding PF00501.28 EGO56457.1 - 3.8e-80 269.5 0.0 4.7e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2012 PF09430.10 EGO56458.1 - 2.3e-21 76.2 0.0 3.2e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 EGO56458.1 - 0.08 12.5 0.0 0.13 11.7 0.0 1.3 2 0 0 2 2 2 0 Suppressor of PMA 1-7 protein WD40 PF00400.32 EGO56459.1 - 0.094 13.6 16.4 1.9 9.5 0.0 6.1 7 0 0 7 7 7 0 WD domain, G-beta repeat CtaG_Cox11 PF04442.14 EGO56460.1 - 1.9e-59 200.0 0.3 6.5e-59 198.3 0.0 1.9 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF4607 PF15380.6 EGO56460.1 - 0.029 13.9 2.5 0.041 13.4 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4607) DUF5399 PF17377.2 EGO56460.1 - 1.1 9.0 5.1 2 8.2 5.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5399) Rav1p_C PF12234.8 EGO56461.1 - 7.7e-287 952.9 0.0 9.6e-287 952.6 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal OPT PF03169.15 EGO56462.1 - 1e-148 496.7 16.2 1.2e-148 496.6 16.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2207 PF09972.9 EGO56462.1 - 0.073 11.8 0.1 0.47 9.1 0.0 2.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF4212 PF13937.6 EGO56462.1 - 0.24 11.8 6.8 3 8.3 0.9 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) Phage_holin_2_1 PF04971.12 EGO56462.1 - 0.66 10.0 4.2 0.31 11.1 0.2 2.5 2 0 0 2 2 2 0 Bacteriophage P21 holin S DENN PF02141.21 EGO56463.1 - 3e-59 200.1 0.0 4.9e-59 199.4 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EGO56463.1 - 4.8e-15 56.1 0.0 1e-14 55.0 0.0 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 EGO56463.1 - 3.1e-13 49.5 0.1 6.4e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 dDENN domain C1_1 PF00130.22 EGO56463.1 - 0.019 14.8 8.1 0.036 13.9 8.1 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EGO56463.1 - 0.035 14.4 8.4 0.067 13.5 8.4 1.5 1 0 0 1 1 1 0 C1 domain Zf_RING PF16744.5 EGO56463.1 - 0.13 12.4 3.2 0.26 11.4 3.2 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger SPA PF08616.10 EGO56463.1 - 0.22 11.5 0.0 0.43 10.5 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis PHD PF00628.29 EGO56463.1 - 0.35 10.8 7.4 0.75 9.7 7.4 1.6 1 0 0 1 1 1 0 PHD-finger DUF974 PF06159.13 EGO56465.1 - 2.5e-72 243.6 0.0 3.1e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) KH_1 PF00013.29 EGO56466.1 - 2.5e-10 40.0 0.0 2.1e-07 30.6 0.0 2.6 2 0 0 2 2 2 2 KH domain DUF2277 PF10041.9 EGO56466.1 - 0.63 10.4 3.2 1.2 9.5 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) ALS_ss_C PF10369.9 EGO56467.1 - 2.9e-14 53.0 0.0 2.5e-13 50.0 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 EGO56467.1 - 9.9e-14 50.8 0.1 1.9e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EGO56467.1 - 2.2e-08 33.8 0.0 4.7e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 EGO56467.1 - 0.12 12.4 0.0 24 5.0 0.0 2.5 2 0 0 2 2 2 0 ACT domain OTCace_N PF02729.21 EGO56468.1 - 4e-43 147.0 0.0 6.1e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EGO56468.1 - 7e-43 146.4 0.0 1.1e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF3712 PF12505.8 EGO56469.1 - 0.0003 21.0 0.0 1.6 9.0 0.0 4.0 4 1 0 4 4 4 2 Protein of unknown function (DUF3712) PrmA PF06325.13 EGO56470.1 - 1.7e-11 44.1 1.4 2.2e-11 43.7 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGO56470.1 - 6.8e-11 42.7 0.0 1.8e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO56470.1 - 1.3e-09 38.0 0.0 2.5e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO56470.1 - 1.4e-08 35.3 0.0 5.9e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO56470.1 - 3.4e-07 30.2 0.0 1.6e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGO56470.1 - 1.1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO56470.1 - 3.2e-06 26.8 0.1 5.6e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EGO56470.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EGO56470.1 - 0.00023 21.8 0.0 0.00053 20.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGO56470.1 - 0.00028 20.7 0.2 0.00069 19.4 0.0 1.7 2 0 0 2 2 2 1 Lysine methyltransferase Met_10 PF02475.16 EGO56470.1 - 0.0019 18.0 0.1 0.0033 17.2 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.20 EGO56470.1 - 0.0059 15.9 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0242 PF06785.11 EGO56470.1 - 0.016 15.3 1.7 0.03 14.4 1.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FtsJ PF01728.19 EGO56470.1 - 0.019 15.1 0.0 0.042 13.9 0.0 1.5 2 0 0 2 2 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 EGO56470.1 - 0.021 13.8 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_24 PF13578.6 EGO56470.1 - 0.025 15.6 0.1 0.19 12.7 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain TehB PF03848.14 EGO56470.1 - 0.042 13.2 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Cons_hypoth95 PF03602.15 EGO56470.1 - 0.081 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Cnn_1N PF07989.11 EGO56470.1 - 0.13 12.4 0.2 0.3 11.3 0.2 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Methyltransf_32 PF13679.6 EGO56470.1 - 0.29 11.1 0.8 1.1 9.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DUF3138 PF11336.8 EGO56470.1 - 0.65 8.5 3.6 0.89 8.1 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PPI_Ypi1 PF07491.11 EGO56471.1 - 1.4e-21 76.1 13.3 1.6e-20 72.7 13.3 2.4 1 1 0 1 1 1 1 Protein phosphatase inhibitor CDC45 PF02724.14 EGO56471.1 - 0.18 10.0 5.3 0.2 9.9 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SelP_N PF04592.14 EGO56471.1 - 5 6.5 8.5 7.9 5.8 8.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF726 PF05277.12 EGO56472.1 - 2.7e-147 490.2 0.1 3.7e-147 489.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF2514 PF10721.9 EGO56472.1 - 0.058 13.4 0.9 0.15 12.1 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Glu-tRNAGln PF02686.15 EGO56473.1 - 0.0041 17.4 0.0 0.014 15.7 0.0 1.8 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.6 EGO56474.1 - 8.1e-105 350.3 21.9 9.2e-105 350.1 21.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EGO56474.1 - 0.00019 21.7 3.9 0.035 14.4 0.1 3.9 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGO56474.1 - 0.0027 17.7 12.5 3.2 8.1 0.3 6.0 4 1 3 7 7 7 2 Tetratricopeptide repeat Spatacsin_C PF14649.6 EGO56474.1 - 0.15 11.1 10.7 0.79 8.8 1.3 3.1 2 1 1 3 3 3 0 Spatacsin C-terminus DUF2225 PF09986.9 EGO56474.1 - 2 8.1 10.5 1.5 8.5 2.2 2.3 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) NUC173 PF08161.12 EGO56475.1 - 7.9e-82 273.8 0.9 5.5e-76 254.8 0.0 4.2 5 0 0 5 5 5 2 NUC173 domain HEAT PF02985.22 EGO56475.1 - 0.0038 17.3 1.2 0.74 10.2 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 EGO56475.1 - 0.027 14.8 2.0 0.26 11.7 0.4 3.6 4 0 0 4 4 4 0 HEAT repeats Nipped-B_C PF12830.7 EGO56475.1 - 0.061 13.3 0.0 0.25 11.3 0.0 2.0 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus DUF3483 PF11982.8 EGO56475.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) TFCD_C PF12612.8 EGO56475.1 - 0.25 11.2 6.6 5.4 6.8 0.0 5.0 5 1 1 6 6 6 0 Tubulin folding cofactor D C terminal Amino_oxidase PF01593.24 EGO56476.1 - 4.1e-19 69.2 0.0 7.1e-17 61.8 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGO56476.1 - 1.6e-11 44.3 0.0 3.8e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGO56476.1 - 7e-08 32.6 0.0 0.014 15.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 EGO56476.1 - 0.00011 21.9 0.2 0.00059 19.5 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO56476.1 - 0.0014 18.0 0.0 0.02 14.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO56476.1 - 0.01 16.4 0.1 0.066 13.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO56476.1 - 0.13 10.9 0.0 7.4 5.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein E1-E2_ATPase PF00122.20 EGO56478.1 - 7.4e-50 169.0 8.3 9.7e-50 168.6 5.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EGO56478.1 - 1.7e-15 57.9 0.0 5.4e-15 56.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGO56478.1 - 1.9e-09 37.1 0.0 4.5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGO56478.1 - 0.0035 17.4 0.1 0.0094 16.0 0.0 1.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGO56478.1 - 0.0094 15.7 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase O-antigen_lig PF13425.6 EGO56478.1 - 0.14 11.0 7.9 0.078 11.8 5.4 1.8 2 0 0 2 2 2 0 O-antigen ligase like membrane protein DUF2613 PF11021.8 EGO56478.1 - 2.6 8.2 7.5 6.5 6.9 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Adipokin_hormo PF06377.11 EGO56481.1 - 0.2 12.0 4.0 1.9 8.9 4.0 2.2 1 1 0 1 1 1 0 Adipokinetic hormone DEC1 PF15859.5 EGO56483.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Deleted in esophageal cancer 1 family Mito_carr PF00153.27 EGO56485.1 - 3.3e-30 103.9 4.6 9.5e-14 51.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.21 EGO56487.1 - 3.7e-102 342.1 0.0 5.3e-102 341.6 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 EGO56487.1 - 0.031 14.0 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone CTD_bind PF04818.13 EGO56488.1 - 1.5e-08 35.3 0.0 3.2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 EGO56488.1 - 2.4e-06 27.3 0.0 4.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 EGO56489.1 - 2.3e-05 25.1 0.0 4.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.8 EGO56489.1 - 0.00012 22.5 0.3 0.0011 19.4 0.5 2.2 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 zf-C2H2_4 PF13894.6 EGO56489.1 - 0.15 13.0 1.3 11 7.2 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf_UBZ PF18439.1 EGO56489.1 - 5.5 6.7 7.0 3.3 7.4 2.2 2.7 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger 4F5 PF04419.14 EGO56491.1 - 2.5e-10 41.0 13.8 2.5e-10 41.0 13.8 2.2 2 0 0 2 2 2 1 4F5 protein family Cu_bind_like PF02298.17 EGO56492.1 - 0.0054 16.7 0.2 0.033 14.2 0.2 2.1 1 1 0 1 1 1 1 Plastocyanin-like domain HupH_C PF04809.13 EGO56492.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region SMN PF06003.12 EGO56493.1 - 4.4e-08 32.7 0.4 0.00016 21.1 0.1 2.2 2 0 0 2 2 2 2 Survival motor neuron protein (SMN) FGGY_C PF02782.16 EGO56494.1 - 1.1e-50 172.1 0.6 1.6e-50 171.6 0.6 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGO56494.1 - 1.5e-20 73.8 0.3 3.1e-18 66.2 0.0 2.8 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 EGO56494.1 - 0.012 15.5 0.0 0.045 13.6 0.0 1.8 2 0 0 2 2 2 0 Hexokinase BcrAD_BadFG PF01869.20 EGO56494.1 - 0.015 14.8 0.2 0.071 12.6 0.0 2.1 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Nic96 PF04097.14 EGO56495.1 - 4.1e-226 752.3 0.0 5e-226 752.0 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 EGO56495.1 - 6.8e-11 42.9 90.8 0.00013 22.7 37.1 4.6 2 1 2 4 4 4 3 Nucleoporin FG repeat region Aldo_ket_red PF00248.21 EGO56496.1 - 1.2e-12 47.7 0.0 2.6e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Aldo/keto reductase family GFO_IDH_MocA PF01408.22 EGO56497.1 - 1.1e-19 71.4 0.4 2.5e-19 70.3 0.4 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EGO56497.1 - 0.009 16.7 0.2 0.015 16.0 0.2 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 EGO56498.1 - 5e-12 46.3 0.9 1.7e-11 44.6 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO56498.1 - 5.9e-11 42.9 0.7 3.3e-10 40.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO56498.1 - 6.8e-08 32.5 0.5 1.8e-07 31.2 0.3 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO56498.1 - 4.9e-06 26.4 0.0 8.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO56498.1 - 5.4e-06 27.1 0.0 5.4e-06 27.1 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO56498.1 - 0.07 12.4 0.0 0.22 10.8 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ndc1_Nup PF09531.10 EGO56498.1 - 0.53 8.9 2.8 0.73 8.4 2.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AAA_25 PF13481.6 EGO56498.1 - 0.99 8.9 4.6 0.17 11.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain Presenilin PF01080.17 EGO56498.1 - 8.8 5.0 6.2 12 4.5 6.2 1.1 1 0 0 1 1 1 0 Presenilin Myb_DNA-binding PF00249.31 EGO56499.1 - 1.9e-14 53.5 3.5 6.2e-11 42.3 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO56499.1 - 3.1e-05 24.1 3.4 0.0072 16.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain CAP_GLY PF01302.25 EGO56506.1 - 5.4e-22 77.6 1.9 7.9e-22 77.1 1.9 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EGO56506.1 - 1.3e-17 64.1 0.0 1.9e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 EGO56506.1 - 0.00011 21.8 0.0 0.0023 17.6 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin family zf-RING_2 PF13639.6 EGO56509.1 - 5.2e-12 45.9 4.3 8.2e-12 45.3 4.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGO56509.1 - 4e-09 36.0 1.0 7.2e-09 35.2 1.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGO56509.1 - 1.2e-06 28.2 3.0 2e-06 27.6 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO56509.1 - 1.6e-06 27.8 3.7 2.6e-06 27.2 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGO56509.1 - 1.7e-05 25.0 4.8 4.2e-05 23.7 4.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGO56509.1 - 0.00012 21.9 4.5 0.0011 18.8 5.2 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGO56509.1 - 0.00022 21.1 1.3 0.00034 20.5 1.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGO56509.1 - 0.0021 17.9 1.7 0.0037 17.1 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO56509.1 - 0.0049 16.9 5.3 0.011 15.7 5.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGO56509.1 - 0.014 15.4 1.0 0.029 14.4 1.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGO56509.1 - 0.029 14.2 3.2 0.052 13.4 3.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF5305 PF17231.2 EGO56509.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Prok-RING_1 PF14446.6 EGO56509.1 - 0.14 12.1 3.4 0.14 12.1 1.6 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 EGO56509.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EGO56509.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.11 EGO56509.1 - 0.23 11.8 1.4 0.39 11.1 1.4 1.4 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 EGO56509.1 - 0.71 9.8 1.8 1.3 9.0 1.8 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 EGO56509.1 - 0.86 9.8 4.2 30 4.9 4.0 3.2 2 1 0 2 2 2 0 FANCL C-terminal domain EOS1 PF12326.8 EGO56511.1 - 0.0074 16.2 0.5 0.022 14.7 0.1 2.0 2 0 0 2 2 2 1 N-glycosylation protein Glyco_hydro_cc PF11790.8 EGO56512.1 - 3.8e-61 206.7 2.2 1.3e-60 205.0 0.8 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core FSA_C PF10479.9 EGO56512.1 - 0.87 7.6 11.5 1.3 7.1 11.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Hamartin PF04388.12 EGO56512.1 - 1.8 7.1 9.1 2.7 6.6 9.1 1.2 1 0 0 1 1 1 0 Hamartin protein Ank_5 PF13857.6 EGO56513.1 - 1.9e-12 47.2 1.0 1.1e-11 44.7 0.3 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGO56513.1 - 1.8e-11 43.9 2.7 3.3e-07 30.4 0.5 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EGO56513.1 - 2.8e-11 43.8 0.1 5.5e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.24 EGO56513.1 - 5.2e-09 36.1 0.5 1.7e-08 34.4 0.5 1.9 1 0 0 1 1 1 1 IPT/TIG domain Ank_3 PF13606.6 EGO56513.1 - 2.4e-07 30.5 0.2 0.00034 20.8 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EGO56513.1 - 2.4e-06 28.0 0.0 1.4e-05 25.6 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Na_H_Exchanger PF00999.21 EGO56515.1 - 1.1e-42 146.2 17.8 1.6e-42 145.7 17.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family dCMP_cyt_deam_1 PF00383.23 EGO56516.1 - 1.6e-10 40.7 0.2 3.9e-10 39.5 0.2 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGO56516.1 - 0.00016 21.4 0.1 0.00035 20.3 0.1 1.5 1 0 0 1 1 1 1 MafB19-like deaminase 6PF2K PF01591.18 EGO56518.1 - 5.6e-65 218.8 0.0 4.3e-45 153.7 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGO56518.1 - 3e-31 108.6 0.1 1e-24 87.4 0.0 2.7 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGO56518.1 - 0.0011 19.2 0.2 2.2 8.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain KTI12 PF08433.10 EGO56518.1 - 0.049 13.1 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CARD PF00619.21 EGO56518.1 - 0.14 12.2 0.1 0.49 10.5 0.1 1.9 1 1 0 1 1 1 0 Caspase recruitment domain HTH_50 PF18024.1 EGO56520.1 - 0.05 13.2 0.1 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Velvet PF11754.8 EGO56523.1 - 5.1e-51 174.0 0.0 7.7e-33 114.5 0.0 3.8 2 2 1 3 3 3 2 Velvet factor Bac_rhodopsin PF01036.18 EGO56525.1 - 4.3e-36 124.6 25.9 5.9e-36 124.1 25.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Methuselah_N PF06652.12 EGO56526.1 - 0.038 13.9 1.0 0.048 13.6 1.0 1.2 1 0 0 1 1 1 0 Methuselah N-terminus Arm PF00514.23 EGO56528.1 - 4e-13 48.9 7.6 0.0003 20.7 0.0 8.3 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGO56528.1 - 0.074 13.4 9.0 38 4.9 0.0 6.5 7 0 0 7 7 7 0 HEAT repeat V-ATPase_H_C PF11698.8 EGO56528.1 - 0.13 12.4 0.4 0.66 10.1 0.0 2.4 3 0 0 3 3 3 0 V-ATPase subunit H HEAT_EZ PF13513.6 EGO56528.1 - 1.8 9.1 8.4 14 6.4 0.0 5.3 6 0 0 6 6 6 0 HEAT-like repeat Cyclin PF08613.11 EGO56529.1 - 4.4e-32 111.7 0.3 1.1e-31 110.4 0.0 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EGO56529.1 - 3.7e-05 23.5 0.0 5.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain UPF0370 PF13980.6 EGO56530.1 - 0.1 12.6 1.1 0.18 11.8 1.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) CHZ PF09649.10 EGO56531.1 - 1.9e-16 59.2 0.4 1.9e-16 59.2 0.4 3.3 4 1 0 4 4 4 1 Histone chaperone domain CHZ BSP_II PF05432.11 EGO56531.1 - 3.9 7.1 22.8 4.4 6.9 22.8 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Use1 PF09753.9 EGO56532.1 - 0.00016 21.5 0.0 0.0002 21.2 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 GRP PF07172.11 EGO56532.1 - 0.062 14.0 11.7 0.11 13.2 11.7 1.5 1 0 0 1 1 1 0 Glycine rich protein family Apc15p PF05841.11 EGO56533.1 - 1e-29 103.8 0.9 1e-29 103.8 0.9 3.1 3 0 0 3 3 3 1 Apc15p protein GATase_2 PF00310.21 EGO56536.1 - 1.1e-184 614.0 0.0 1.6e-184 613.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EGO56536.1 - 3.1e-154 513.6 0.0 4.5e-154 513.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EGO56536.1 - 1.4e-109 365.9 0.0 5.3e-108 360.7 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EGO56536.1 - 5.5e-88 293.5 2.9 9e-88 292.9 2.9 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EGO56536.1 - 2.4e-23 82.8 0.1 1.4e-22 80.3 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EGO56536.1 - 2.1e-21 75.8 0.1 4.5e-21 74.7 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 EGO56536.1 - 9.7e-09 35.3 0.0 3.2e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGO56536.1 - 2.6e-07 31.1 0.1 0.00012 22.5 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO56536.1 - 8.6e-07 28.9 0.2 0.002 17.8 0.1 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EGO56536.1 - 1.2e-06 28.2 0.1 2.5e-06 27.1 0.1 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EGO56536.1 - 2.3e-06 27.1 0.1 0.017 14.4 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO56536.1 - 3.4e-05 23.4 0.2 6.9e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO56536.1 - 3.6e-05 23.0 0.1 0.00013 21.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EGO56536.1 - 4.3e-05 22.4 0.2 4.3e-05 22.4 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.6 EGO56536.1 - 0.00041 20.7 0.4 0.46 10.9 0.1 3.0 3 0 0 3 3 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EGO56536.1 - 0.0006 19.2 0.0 0.0013 18.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.19 EGO56536.1 - 0.0012 17.4 0.2 0.51 8.7 0.0 2.8 2 1 0 3 3 3 2 Flavin-binding monooxygenase-like Thi4 PF01946.17 EGO56536.1 - 0.0018 17.6 0.1 0.011 14.9 0.1 2.3 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 EGO56536.1 - 0.0051 16.1 0.1 0.41 9.9 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.23 EGO56536.1 - 0.0074 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 EGO56536.1 - 0.016 14.3 1.1 0.064 12.3 0.1 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A FMN_dh PF01070.18 EGO56536.1 - 0.037 13.1 0.6 0.12 11.4 0.6 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Lycopene_cycl PF05834.12 EGO56536.1 - 0.037 13.1 0.2 0.18 10.8 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein IlvN PF07991.12 EGO56536.1 - 0.079 12.5 0.1 0.23 11.0 0.1 1.8 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 EGO56536.1 - 0.17 11.5 0.1 0.75 9.4 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 EGO56536.1 - 0.21 11.7 0.3 34 4.5 0.0 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase VTC PF09359.10 EGO56537.1 - 6e-93 311.2 2.2 1e-92 310.5 2.2 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 EGO56537.1 - 1.6e-10 41.3 4.4 1.6e-10 41.3 4.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 EGO56537.1 - 4e-09 36.9 25.5 2.5e-06 27.7 0.8 4.3 2 1 2 4 4 4 2 SPX domain Lebercilin PF15619.6 EGO56537.1 - 0.024 14.3 4.7 0.051 13.2 4.7 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4600 PF15372.6 EGO56537.1 - 0.025 15.0 0.9 0.06 13.8 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) bZIP_2 PF07716.15 EGO56537.1 - 0.18 11.9 7.8 1.2 9.3 1.4 2.7 2 0 0 2 2 2 0 Basic region leucine zipper Tropomyosin_1 PF12718.7 EGO56537.1 - 1 9.5 9.9 0.45 10.7 6.1 2.2 3 0 0 3 3 3 0 Tropomyosin like DUF4140 PF13600.6 EGO56537.1 - 6.8 7.2 6.7 1.2e+02 3.3 6.7 2.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Ctf8 PF09696.10 EGO56538.1 - 2.4e-24 86.3 0.0 4.5e-24 85.4 0.0 1.4 1 1 0 1 1 1 1 Ctf8 GDPD PF03009.17 EGO56539.1 - 1.6e-44 152.6 0.0 2.2e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family WW PF00397.26 EGO56540.1 - 1.1e-10 41.4 0.7 2.6e-10 40.2 0.7 1.7 1 0 0 1 1 1 1 WW domain ABC_membrane_2 PF06472.15 EGO56541.1 - 3.2e-104 348.1 1.7 5e-104 347.5 1.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGO56541.1 - 2.1e-17 63.9 0.0 1.1e-16 61.5 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGO56541.1 - 0.0003 20.7 0.0 0.00061 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system RuvB_N PF05496.12 EGO56541.1 - 0.021 14.6 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 EGO56541.1 - 0.033 14.7 0.2 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EGO56541.1 - 0.099 12.1 0.0 0.29 10.5 0.0 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGO56541.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EGO56541.1 - 0.13 11.6 0.1 0.64 9.4 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EGO56541.1 - 0.28 11.6 3.5 0.47 10.8 0.2 2.7 3 0 0 3 3 3 0 AAA ATPase domain G_glu_transpept PF01019.21 EGO56545.1 - 3.6e-183 610.0 0.0 4.2e-183 609.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase ADH_N PF08240.12 EGO56546.1 - 5.9e-30 103.4 0.7 1.1e-29 102.6 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO56546.1 - 3.4e-24 85.3 0.1 6.2e-24 84.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO56546.1 - 1.7e-08 35.6 0.1 2.8e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGO56546.1 - 0.037 13.3 0.4 0.058 12.7 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2226 PF09987.9 EGO56546.1 - 0.089 12.1 0.1 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) adh_short PF00106.25 EGO56546.1 - 0.1 12.0 0.9 0.23 10.9 0.9 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Actin PF00022.19 EGO56547.1 - 5.8e-88 295.2 0.0 1.7e-85 287.1 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGO56547.1 - 0.072 11.9 0.0 2.9 6.6 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.18 EGO56548.1 - 6.7e-46 156.7 0.5 2.3e-29 102.4 0.0 2.2 2 0 0 2 2 2 2 Asparaginase UPF0061 PF02696.14 EGO56549.1 - 6.5e-124 414.2 0.0 8.4e-124 413.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family BORA_N PF15280.6 EGO56549.1 - 0.022 14.4 0.1 0.035 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein aurora borealis N-terminus Aldo_ket_red PF00248.21 EGO56550.1 - 1.1e-42 146.3 0.0 1.6e-41 142.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family FANCI_S1-cap PF14674.6 EGO56550.1 - 0.18 12.0 0.0 0.6 10.2 0.0 1.9 2 0 0 2 2 2 0 FANCI solenoid 1 cap PUF PF00806.19 EGO56551.1 - 8.4e-39 129.1 0.4 3.4e-06 26.4 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RasGEF PF00617.19 EGO56551.1 - 0.079 13.2 0.1 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 RasGEF domain MRP-S33 PF08293.11 EGO56552.1 - 4.6e-23 81.3 0.0 5.2e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 RRP14 PF15459.6 EGO56552.1 - 0.089 13.4 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Ribonuclease_3 PF00636.26 EGO56553.1 - 1.3e-14 54.7 0.0 7.5e-14 52.2 0.0 2.2 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGO56553.1 - 1.3e-13 51.2 0.0 1.6e-12 47.7 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.26 EGO56553.1 - 0.076 13.7 0.0 0.076 13.7 0.0 2.5 2 0 0 2 2 2 0 Double-stranded RNA binding motif BRF1 PF07741.13 EGO56553.1 - 8.6 6.8 8.1 2.7 8.4 3.0 2.3 1 1 1 2 2 2 0 Brf1-like TBP-binding domain ACBP PF00887.19 EGO56554.1 - 2e-24 85.6 0.0 4.4e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein PRCC PF10253.9 EGO56554.1 - 0.026 15.3 1.1 0.04 14.7 1.1 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting BatD PF13584.6 EGO56554.1 - 0.08 11.7 0.6 0.13 11.1 0.6 1.3 1 0 0 1 1 1 0 Oxygen tolerance Molybdopterin PF00384.22 EGO56556.1 - 1.6e-78 264.6 0.0 1.4e-76 258.2 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 EGO56556.1 - 9e-21 73.7 0.1 2.2e-20 72.5 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 EGO56556.1 - 1.3e-18 67.4 0.0 3.7e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 EGO56556.1 - 7.9e-17 60.5 0.2 7.9e-17 60.5 0.2 2.3 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 EGO56556.1 - 2.8e-09 36.8 0.5 2.8e-09 36.8 0.5 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 EGO56556.1 - 0.014 15.2 0.0 0.37 10.5 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Lyx_isomer PF07385.12 EGO56556.1 - 0.058 12.6 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 D-lyxose isomerase Fer4 PF00037.27 EGO56556.1 - 0.18 11.7 1.1 4.9 7.1 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain DUF5572 PF17733.1 EGO56557.1 - 7.7e-15 54.5 3.6 7.7e-15 54.5 3.6 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5572) PP2C PF00481.21 EGO56558.1 - 4.7e-44 151.0 0.0 7.8e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGO56558.1 - 0.00031 20.7 0.1 0.48 10.3 0.0 3.2 4 0 0 4 4 4 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EGO56558.1 - 0.00069 19.3 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C Glyco_hydro_63 PF03200.16 EGO56559.1 - 1.1e-09 37.7 2.2 9.4e-08 31.2 2.2 3.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain TTSSLRR PF12468.8 EGO56559.1 - 0.09 13.0 0.5 0.34 11.2 0.1 2.2 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein Podoplanin PF05808.11 EGO56560.1 - 0.0069 16.5 1.2 0.011 15.8 1.2 1.3 1 0 0 1 1 1 1 Podoplanin DUF202 PF02656.15 EGO56560.1 - 0.18 12.3 0.5 0.55 10.7 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF5305 PF17231.2 EGO56560.1 - 0.31 10.4 0.0 0.43 9.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) RNA_pol_Rpb2_6 PF00562.28 EGO56562.1 - 5.5e-119 397.7 0.1 8.1e-119 397.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGO56562.1 - 1.7e-49 168.1 0.0 2.5e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EGO56562.1 - 1.6e-33 115.0 0.9 3.5e-33 113.9 0.9 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EGO56562.1 - 9.6e-31 106.9 0.0 3.7e-30 105.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EGO56562.1 - 1.7e-22 79.5 0.6 4.1e-22 78.2 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EGO56562.1 - 3.3e-19 68.8 0.0 6.6e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EGO56562.1 - 1.2e-10 41.7 0.4 4.4e-10 40.0 0.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 FapA PF03961.13 EGO56563.1 - 0.05 12.2 1.1 0.064 11.8 1.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PUF PF00806.19 EGO56564.1 - 1.9e-65 213.0 11.7 3.9e-08 32.6 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Ribosomal_L15e PF00827.17 EGO56565.1 - 4.5e-90 300.5 10.5 5.5e-90 300.2 10.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 Exonuc_VII_S PF02609.16 EGO56566.1 - 0.0055 16.7 0.3 0.023 14.7 0.0 2.0 2 0 0 2 2 2 1 Exonuclease VII small subunit PSP1 PF04468.12 EGO56567.1 - 5e-28 97.2 1.6 8.8e-28 96.4 1.6 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Nfu_N PF08712.11 EGO56570.1 - 1e-29 102.4 0.2 2.8e-29 101.0 0.1 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EGO56570.1 - 2.1e-28 98.2 0.2 3.8e-28 97.4 0.2 1.5 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 EGO56570.1 - 0.12 12.4 0.3 0.89 9.7 0.3 2.1 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus zf-HIT PF04438.16 EGO56571.1 - 6.7e-10 38.7 9.4 1e-09 38.1 9.4 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 EGO56571.1 - 6.7e-05 22.9 7.5 0.00017 21.6 7.5 1.7 1 0 0 1 1 1 1 MYND finger Exonuc_VII_L PF02601.15 EGO56571.1 - 0.018 14.6 14.0 0.025 14.2 14.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Otopetrin PF03189.13 EGO56571.1 - 0.057 12.2 6.5 0.083 11.7 6.5 1.3 1 0 0 1 1 1 0 Otopetrin DUF2828 PF11443.8 EGO56571.1 - 0.52 8.3 20.7 1 7.4 20.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) ABC2_membrane_2 PF12679.7 EGO56571.1 - 0.62 9.3 3.1 0.87 8.8 3.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Peptidase_S49_N PF08496.10 EGO56571.1 - 0.65 10.0 14.5 2.2 8.4 14.5 1.9 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Lant_dehydr_C PF14028.6 EGO56571.1 - 0.79 9.2 10.1 1.6 8.2 10.1 1.5 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term Bud13 PF09736.9 EGO56571.1 - 1.3 9.4 28.1 0.042 14.2 20.0 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex DUF913 PF06025.12 EGO56571.1 - 1.8 7.5 22.7 0.011 14.8 12.2 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF2126 PF09899.9 EGO56571.1 - 2.2 6.2 15.1 3.6 5.6 15.1 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SpoIIP PF07454.11 EGO56571.1 - 2.7 7.4 31.4 0.017 14.6 19.9 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) LMBR1 PF04791.16 EGO56571.1 - 3.9 6.3 12.5 5 5.9 12.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Connexin PF00029.19 EGO56571.1 - 4.4 7.0 19.3 0.15 11.8 12.9 1.8 2 0 0 2 2 2 0 Connexin Serinc PF03348.15 EGO56571.1 - 5.6 5.8 13.9 9.2 5.1 13.9 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.12 EGO56571.1 - 6.4 6.5 35.0 0.51 10.1 23.3 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 EGO56571.1 - 6.5 5.5 28.3 0.15 10.9 21.8 1.4 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 CLN3 PF02487.17 EGO56571.1 - 8.7 5.3 19.6 17 4.3 19.6 1.4 1 0 0 1 1 1 0 CLN3 protein TERB2 PF15101.6 EGO56571.1 - 9.6 6.2 38.2 1.4 8.9 27.8 2.4 2 0 0 2 2 2 0 Telomere-associated protein TERB2 RasGEF PF00617.19 EGO56573.1 - 4.3e-43 147.5 0.3 6.6e-43 147.0 0.3 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGO56573.1 - 3.4e-11 43.3 0.0 7.9e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 EGO56573.1 - 4.1e-05 23.3 0.0 0.00049 19.7 0.0 2.5 2 1 0 2 2 2 1 Ras family Roc PF08477.13 EGO56573.1 - 0.18 12.0 0.0 13 6.0 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PIG-H PF10181.9 EGO56574.1 - 7.5e-27 93.0 0.2 1.1e-26 92.4 0.2 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.20 EGO56575.1 - 2.5e-35 121.2 0.0 5.5e-35 120.1 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridine synthase Ras PF00071.22 EGO56576.1 - 5.4e-16 58.6 0.0 7.6e-14 51.6 0.0 2.2 1 1 0 1 1 1 1 Ras family AAA_24 PF13479.6 EGO56576.1 - 0.0037 17.0 0.0 0.009 15.8 0.0 1.6 1 1 0 2 2 2 1 AAA domain Arf PF00025.21 EGO56576.1 - 0.0057 16.1 0.0 0.12 11.8 0.0 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGO56576.1 - 0.0079 16.4 0.0 1.3 9.3 0.0 2.4 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RNA_pol_Rpb4 PF03874.16 EGO56577.1 - 1.6e-23 83.4 2.8 1.9e-23 83.1 2.8 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 MMS19_C PF12460.8 EGO56577.1 - 0.0003 20.0 0.1 0.00033 19.9 0.1 1.0 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal DAHP_snth_FXD PF18152.1 EGO56577.1 - 0.026 14.3 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain Glyco_transf_54 PF04666.13 EGO56577.1 - 0.068 12.0 0.1 0.071 12.0 0.1 1.2 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Pribosyl_synth PF14572.6 EGO56578.1 - 4.7e-38 131.1 1.0 4.7e-33 114.8 0.5 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EGO56578.1 - 8.5e-30 103.1 0.0 2.1e-29 101.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EGO56578.1 - 9.5e-15 54.5 0.1 1.5e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGO56578.1 - 0.0041 16.6 0.1 0.0075 15.7 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase SLAC1 PF03595.17 EGO56579.1 - 3.3e-57 194.2 35.9 4.3e-54 183.9 27.9 2.1 1 1 1 2 2 2 2 Voltage-dependent anion channel Snf7 PF03357.21 EGO56585.1 - 4.3e-23 81.8 9.9 4.3e-23 81.8 9.9 1.8 1 1 1 2 2 2 1 Snf7 Fib_alpha PF08702.10 EGO56585.1 - 1.4 9.1 9.5 0.42 10.8 6.1 1.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3484 PF11983.8 EGO56585.1 - 9.8 7.4 11.6 8 7.7 7.1 2.8 2 1 1 3 3 3 0 Membrane-attachment and polymerisation-promoting switch CS PF04969.16 EGO56586.1 - 1.2e-05 26.2 0.0 1.9e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 CS domain RRM_1 PF00076.22 EGO56588.1 - 6.3e-16 58.0 0.0 1.1e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO56588.1 - 0.005 16.7 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif FoP_duplication PF13865.6 EGO56588.1 - 0.0052 17.3 0.4 0.0052 17.3 0.4 2.9 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_3 PF08777.11 EGO56588.1 - 0.099 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Ost4 PF10215.9 EGO56589.1 - 5.6e-17 61.3 0.2 8.6e-17 60.7 0.2 1.3 1 0 0 1 1 1 1 Oligosaccaryltransferase Afaf PF15339.6 EGO56589.1 - 0.01 15.6 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 0 Acrosome formation-associated factor DFRP_C PF16543.5 EGO56590.1 - 1.8e-26 92.5 5.8 1.8e-26 92.5 5.8 3.7 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 EGO56590.1 - 4.8e-07 30.5 13.2 2.4e-06 28.2 3.7 3.3 2 1 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 EGO56590.1 - 9.1e-06 25.5 1.0 9.1e-06 25.5 1.0 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGO56590.1 - 2.5e-05 23.9 8.8 0.00049 19.8 2.2 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGO56590.1 - 0.00013 21.9 6.7 0.00013 21.9 6.7 3.1 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_3 PF15663.5 EGO56590.1 - 0.025 14.8 3.0 0.58 10.4 1.9 2.7 2 1 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGO56590.1 - 0.067 13.7 16.0 0.35 11.4 6.7 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger AT_hook PF02178.19 EGO56591.1 - 4 7.6 14.9 9 6.6 5.2 3.4 2 0 0 2 2 2 0 AT hook motif Pkinase PF00069.25 EGO56592.1 - 1.4e-75 254.1 0.0 1.9e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO56592.1 - 1.4e-30 106.4 0.0 7.1e-22 77.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGO56592.1 - 1.8e-07 30.8 0.1 0.51 9.6 0.0 3.1 3 0 0 3 3 3 3 Kinase-like APH PF01636.23 EGO56592.1 - 0.011 15.7 0.0 0.73 9.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGO56592.1 - 0.014 14.2 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EGO56592.1 - 0.023 14.1 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DASH_Dad3 PF08656.10 EGO56594.1 - 1.2e-32 111.7 0.3 1.5e-32 111.5 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Lipase_GDSL PF00657.22 EGO56594.1 - 0.1 12.6 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Ribosomal_S5_C PF03719.15 EGO56595.1 - 3.2e-23 80.9 0.0 1.4e-22 78.9 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EGO56595.1 - 4.2e-19 68.3 0.2 9.3e-19 67.2 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain N_NLPC_P60 PF12912.7 EGO56595.1 - 0.056 13.8 1.5 0.14 12.5 1.5 1.7 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term DUF4834 PF16118.5 EGO56596.1 - 0.11 13.5 0.0 0.12 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ATE_C PF04377.15 EGO56598.1 - 5.5e-46 156.5 0.1 9.2e-46 155.8 0.1 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EGO56598.1 - 3.7e-20 72.1 0.1 8.3e-20 71.0 0.1 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus NUDIX PF00293.28 EGO56599.1 - 1.8e-16 60.3 2.1 2.3e-16 60.0 2.1 1.1 1 0 0 1 1 1 1 NUDIX domain COG5 PF10392.9 EGO56600.1 - 0.02 15.1 2.6 0.036 14.2 0.5 2.4 2 1 0 2 2 2 0 Golgi transport complex subunit 5 GOLGA2L5 PF15070.6 EGO56600.1 - 0.16 10.6 0.0 0.16 10.6 0.0 1.9 2 1 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 DUF4404 PF14357.6 EGO56600.1 - 0.87 10.3 5.6 0.8 10.4 0.8 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) RNase_PH PF01138.21 EGO56601.1 - 6e-13 49.4 0.0 1.4e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGO56601.1 - 0.0031 17.5 0.1 0.006 16.6 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cytochrom_C PF00034.21 EGO56603.1 - 1.8e-11 45.0 0.1 2.5e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EGO56603.1 - 2.1e-08 34.4 2.2 6.6e-08 32.8 2.2 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EGO56603.1 - 0.0017 18.0 0.2 0.012 15.3 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.14 EGO56603.1 - 0.12 13.1 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase AAA PF00004.29 EGO56604.1 - 9.1e-86 285.0 0.0 2.4e-46 157.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO56604.1 - 1.9e-17 62.8 0.1 1e-08 34.9 0.0 3.2 2 1 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EGO56604.1 - 3.7e-14 52.8 0.0 9e-07 28.8 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGO56604.1 - 2e-09 37.6 1.7 0.00016 21.7 0.0 4.0 4 2 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO56604.1 - 2.3e-09 37.9 15.8 0.0012 19.2 0.1 5.9 5 2 2 7 7 6 2 AAA ATPase domain AAA_33 PF13671.6 EGO56604.1 - 2.5e-09 37.4 0.0 0.00072 19.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGO56604.1 - 3.9e-09 36.9 1.6 0.0086 16.3 0.0 4.6 3 2 0 4 4 3 2 AAA domain AAA_2 PF07724.14 EGO56604.1 - 2.2e-08 34.4 0.0 0.00025 21.2 0.0 3.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 EGO56604.1 - 5.9e-07 29.6 0.0 0.053 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGO56604.1 - 2.1e-06 28.3 1.0 0.16 12.5 0.0 3.7 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 EGO56604.1 - 2.2e-06 28.0 0.0 0.13 12.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 EGO56604.1 - 3.2e-06 27.7 1.2 0.039 14.5 0.0 3.2 3 1 0 3 3 2 2 ABC transporter TIP49 PF06068.13 EGO56604.1 - 4.3e-06 26.2 0.1 0.092 11.9 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain Rad17 PF03215.15 EGO56604.1 - 5.9e-06 26.3 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain IstB_IS21 PF01695.17 EGO56604.1 - 7.9e-06 25.7 0.3 0.083 12.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 EGO56604.1 - 9.4e-06 25.6 0.0 0.031 14.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 EGO56604.1 - 3.9e-05 22.9 0.0 0.033 13.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EGO56604.1 - 5e-05 23.1 0.0 0.46 10.2 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 EGO56604.1 - 6.4e-05 22.4 0.7 0.1 12.0 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGO56604.1 - 7.9e-05 22.9 4.9 0.14 12.4 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.6 EGO56604.1 - 0.00011 21.8 3.4 0.94 9.0 0.1 4.1 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.12 EGO56604.1 - 0.00019 20.8 0.1 0.16 11.3 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 EGO56604.1 - 0.00022 20.8 0.0 0.7 9.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 EGO56604.1 - 0.00024 20.5 0.1 1.2 8.4 0.0 3.1 3 0 0 3 3 3 2 KaiC AAA_24 PF13479.6 EGO56604.1 - 0.00037 20.3 0.1 1 9.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 EGO56604.1 - 0.00038 19.7 0.4 0.37 9.9 0.1 2.8 2 0 0 2 2 2 2 NB-ARC domain NACHT PF05729.12 EGO56604.1 - 0.00038 20.4 2.1 0.11 12.4 0.2 3.3 3 0 0 3 3 3 1 NACHT domain Bac_DnaA PF00308.18 EGO56604.1 - 0.00068 19.5 0.2 0.22 11.4 0.0 3.2 3 1 0 3 3 2 1 Bacterial dnaA protein Cytidylate_kin2 PF13189.6 EGO56604.1 - 0.003 17.7 0.0 1.6 8.8 0.0 2.8 2 0 0 2 2 2 1 Cytidylate kinase-like family Viral_helicase1 PF01443.18 EGO56604.1 - 0.003 17.3 0.0 0.82 9.4 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Cytidylate_kin PF02224.18 EGO56604.1 - 0.0031 17.3 0.5 0.78 9.4 0.2 2.5 2 0 0 2 2 2 1 Cytidylate kinase AAA_3 PF07726.11 EGO56604.1 - 0.0032 17.3 0.2 2.4 8.0 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EGO56604.1 - 0.0079 16.1 0.2 3.2 7.6 0.1 2.8 2 0 0 2 2 2 1 NTPase AAA_29 PF13555.6 EGO56604.1 - 0.01 15.6 0.1 0.36 10.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain PduV-EutP PF10662.9 EGO56604.1 - 0.011 15.5 0.0 0.82 9.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.6 EGO56604.1 - 0.017 15.2 0.0 0.95 9.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain SKI PF01202.22 EGO56604.1 - 0.029 14.5 3.7 3.3 7.8 0.0 3.0 3 0 0 3 3 2 0 Shikimate kinase ATPase_2 PF01637.18 EGO56604.1 - 0.046 13.6 5.1 4.5 7.1 0.0 3.7 4 1 0 4 4 3 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EGO56604.1 - 0.055 13.3 8.2 0.79 9.5 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_17 PF13207.6 EGO56604.1 - 0.056 13.9 7.6 2.2 8.7 0.0 4.5 5 0 0 5 5 4 0 AAA domain PhoH PF02562.16 EGO56604.1 - 0.057 12.9 2.0 4.2 6.8 0.3 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 EGO56604.1 - 0.094 13.0 0.1 9.8 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 EGO56604.1 - 0.11 12.6 0.1 0.8 9.8 0.1 2.5 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain ResIII PF04851.15 EGO56604.1 - 0.11 12.5 0.0 7.1 6.6 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.17 EGO56604.1 - 0.12 11.4 0.4 6.1 5.9 0.1 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 SRPRB PF09439.10 EGO56604.1 - 0.22 10.9 2.5 16 4.8 0.0 3.4 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit 7TMR-HDED PF07697.11 EGO56604.1 - 0.43 10.7 6.2 0.53 10.4 0.1 3.1 3 0 0 3 3 3 0 7TM-HD extracellular Mito_carr PF00153.27 EGO56606.1 - 1.3e-40 137.2 8.9 1.8e-14 53.4 0.5 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein TMEM154 PF15102.6 EGO56608.1 - 3 7.7 0.0 3 7.7 0.0 2.7 2 1 0 3 3 3 0 TMEM154 protein family Sugar_tr PF00083.24 EGO56609.1 - 3.9e-103 345.7 14.9 4.7e-103 345.5 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO56609.1 - 4.2e-29 101.6 25.9 4.5e-28 98.2 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGO56609.1 - 1.7e-09 36.8 22.2 1.8e-07 30.1 5.1 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_5 PF05631.14 EGO56609.1 - 0.0028 16.6 2.1 0.0028 16.6 2.1 2.1 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 EGO56609.1 - 0.016 14.1 8.1 0.15 10.9 0.3 2.4 2 1 0 2 2 2 0 MFS_1 like family Herpes_pp38 PF04846.13 EGO56609.1 - 0.21 11.5 0.9 1.6 8.7 0.5 2.5 2 0 0 2 2 2 0 Herpesvirus pp38 phosphoprotein MFS_3 PF05977.13 EGO56609.1 - 0.44 8.9 5.2 0.42 8.9 1.2 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2530 PF10745.9 EGO56609.1 - 0.46 10.7 3.4 1.4 9.2 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Chs7 PF12271.8 EGO56610.1 - 5.1e-90 301.7 9.6 6.5e-90 301.4 9.6 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Cytochrom_B561 PF03188.16 EGO56611.1 - 1.5e-18 67.2 4.4 3e-18 66.3 4.4 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Prion_bPrPp PF11587.8 EGO56611.1 - 0.98 9.3 3.1 13 5.8 0.5 2.6 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal Ni_hydr_CYTB PF01292.20 EGO56611.1 - 1.4 8.4 16.2 0.55 9.8 1.2 2.7 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF4079 PF13301.6 EGO56611.1 - 2.4 8.3 16.5 3.3 7.8 6.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Allantoicase PF03561.15 EGO56612.1 - 1.2e-96 320.4 0.1 3e-48 163.5 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat DIL PF01843.19 EGO56613.1 - 1.4e-30 105.6 0.5 3.3e-30 104.4 0.5 1.7 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 EGO56613.1 - 3.6e-14 53.1 0.1 6.7e-13 49.0 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO56613.1 - 4.9e-12 46.1 0.1 5.4e-07 30.0 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO56613.1 - 2.3e-09 37.3 0.0 8.4e-05 22.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGO56613.1 - 6.2e-09 35.9 0.0 0.027 14.9 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 EGO56613.1 - 1.9e-05 24.7 0.0 0.11 13.1 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat GTP-bdg_M PF16360.5 EGO56613.1 - 0.11 13.0 0.1 0.47 11.1 0.1 2.0 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region RabGAP-TBC PF00566.18 EGO56614.1 - 2.9e-33 115.3 0.0 5.2e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain YdjM PF04307.14 EGO56614.1 - 0.67 9.2 3.2 1.2 8.4 3.2 1.3 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase DUF2722 PF10846.8 EGO56615.1 - 2.9e-05 23.2 0.1 2.9e-05 23.2 0.1 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF2722) PDCD7 PF16021.5 EGO56615.1 - 0.012 14.8 0.3 0.018 14.2 0.3 1.2 1 0 0 1 1 1 0 Programmed cell death protein 7 SelP_N PF04592.14 EGO56615.1 - 5.2 6.4 11.6 15 4.9 11.6 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CRM1_C PF08767.11 EGO56617.1 - 1.6e-133 444.8 5.4 2.8e-133 444.0 2.2 2.5 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 EGO56617.1 - 2.8e-40 137.8 6.9 2.8e-40 137.8 6.9 3.6 3 1 1 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EGO56617.1 - 3.2e-34 116.4 4.6 1.1e-33 114.7 4.6 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EGO56617.1 - 9.1e-28 96.1 5.4 9.9e-28 96.0 1.2 3.5 4 0 0 4 4 4 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EGO56617.1 - 9.8e-19 66.6 1.8 9.8e-19 66.6 1.8 2.1 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EGO56617.1 - 8e-14 51.3 0.1 3.3e-13 49.4 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 EGO56617.1 - 0.0037 17.2 0.5 0.32 10.9 0.0 3.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) BID PF06393.11 EGO56617.1 - 0.037 13.6 0.1 0.11 12.1 0.1 1.8 1 0 0 1 1 1 0 BH3 interacting domain (BID) Vac14_Fab1_bd PF12755.7 EGO56617.1 - 0.096 13.3 2.9 2.7 8.7 0.0 4.4 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Hemocyanin_M PF00372.19 EGO56617.1 - 0.11 11.6 0.7 7.5 5.7 0.0 2.5 1 1 1 2 2 2 0 Hemocyanin, copper containing domain Aminotran_5 PF00266.19 EGO56618.1 - 6.6e-30 104.3 0.0 8.6e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Metallophos_2 PF12850.7 EGO56619.1 - 1.2e-13 51.6 0.0 1.9e-13 50.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EGO56619.1 - 0.0029 18.2 0.0 0.022 15.3 0.0 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase HATPase_c PF02518.26 EGO56620.1 - 3.1e-30 104.9 0.1 7.4e-30 103.7 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGO56620.1 - 1.2e-20 73.8 0.1 2.7e-20 72.6 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGO56620.1 - 2e-18 66.2 0.5 6.8e-18 64.5 0.5 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 EGO56620.1 - 5.9e-14 52.8 0.0 5.2e-13 49.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.6 EGO56620.1 - 5e-12 46.3 0.0 2.1e-11 44.3 0.0 2.2 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 EGO56620.1 - 3.9e-10 39.5 0.2 1.1e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain GAF PF01590.26 EGO56620.1 - 3.2e-07 31.1 0.0 1.1e-06 29.3 0.0 2.0 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.17 EGO56620.1 - 2.7e-05 23.6 0.0 5.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_MalT PF17874.1 EGO56620.1 - 5.6e-05 22.7 3.5 0.013 14.8 0.7 2.5 2 0 0 2 2 2 2 MalT-like TPR region HATPase_c_3 PF13589.6 EGO56620.1 - 0.00016 21.5 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NACHT PF05729.12 EGO56620.1 - 0.012 15.6 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain TPR_8 PF13181.6 EGO56620.1 - 0.035 14.3 0.3 2.9 8.3 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGO56620.1 - 0.13 12.0 0.3 0.75 9.5 0.2 2.4 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 EGO56620.1 - 0.22 12.4 5.3 5.3 8.1 0.5 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGO56620.1 - 0.33 11.3 12.3 1.5 9.2 1.5 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat NAD_binding_8 PF13450.6 EGO56621.1 - 5.8e-08 32.9 0.1 1.3e-07 31.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGO56621.1 - 8.4e-08 31.9 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EGO56621.1 - 0.00054 19.3 0.1 0.044 13.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGO56621.1 - 0.012 14.9 0.1 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EGO56621.1 - 0.013 14.8 0.1 0.022 14.0 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO56621.1 - 0.028 14.0 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGO56621.1 - 0.031 13.6 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 EGO56621.1 - 0.045 13.0 0.5 0.089 12.0 0.1 1.7 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 EGO56621.1 - 0.067 11.9 0.1 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 EGO56621.1 - 0.091 11.8 0.2 0.16 11.0 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGO56621.1 - 0.13 11.3 0.2 0.2 10.7 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 EGO56621.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain TPT PF03151.16 EGO56622.1 - 1e-24 87.4 24.0 1.5e-24 86.9 24.0 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EGO56622.1 - 0.00021 20.6 25.9 0.00083 18.7 25.9 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGO56622.1 - 0.00034 20.8 11.9 0.00034 20.8 11.9 2.8 3 0 0 3 3 3 2 EamA-like transporter family Ribosomal_L27e PF01777.18 EGO56623.1 - 1.6e-37 127.7 4.3 2.2e-37 127.3 4.3 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EGO56623.1 - 0.015 15.3 0.4 0.045 13.7 0.1 2.0 2 0 0 2 2 2 0 KOW motif NCE101 PF11654.8 EGO56624.1 - 7.7e-13 47.9 0.0 9.4e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 Non-classical export protein 1 DUF5344 PF17279.2 EGO56625.1 - 0.095 13.3 0.7 2 9.1 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Glyoxalase PF00903.25 EGO56626.1 - 1.2e-20 74.0 0.1 1.1e-13 51.5 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGO56626.1 - 2.4e-12 47.1 0.1 6.4e-06 26.4 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EGO56626.1 - 0.001 19.2 0.0 0.6 10.2 0.0 3.0 3 0 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_5 PF14696.6 EGO56626.1 - 0.0096 16.1 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF948 PF06103.11 EGO56626.1 - 0.11 12.8 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Ssl1 PF04056.14 EGO56627.1 - 7.5e-59 198.8 0.0 2.6e-35 122.0 0.0 2.2 1 1 1 2 2 2 2 Ssl1-like VWA_2 PF13519.6 EGO56627.1 - 5.9e-07 30.1 0.0 1.9e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain DZR PF12773.7 EGO56627.1 - 3.2 7.9 9.3 21 5.3 8.2 2.4 1 1 1 2 2 2 0 Double zinc ribbon HATPase_c PF02518.26 EGO56628.1 - 1.1e-25 90.3 0.4 2.5e-25 89.2 0.4 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 EGO56628.1 - 2.1e-23 82.4 0.3 2e-13 50.4 0.1 3.8 3 0 0 3 3 3 3 PAS fold Response_reg PF00072.24 EGO56628.1 - 2.4e-20 72.8 0.0 1e-19 70.8 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EGO56628.1 - 1.7e-19 69.6 0.1 3.7e-19 68.5 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EGO56628.1 - 2.1e-12 47.2 0.0 0.00047 20.4 0.0 3.8 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 EGO56628.1 - 1.3e-10 41.5 0.1 2.7e-07 30.8 0.1 3.1 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 EGO56628.1 - 3e-08 33.6 0.0 0.014 15.4 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 EGO56628.1 - 0.00041 20.3 0.0 0.33 11.0 0.0 2.6 2 0 0 2 2 2 2 PAS domain Ecl1 PF12855.7 EGO56631.1 - 3.3e-15 57.7 26.7 1.1e-13 52.7 26.7 2.0 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 EGO56631.1 - 0.13 12.4 2.1 0.32 11.1 2.1 1.6 1 0 0 1 1 1 0 MYND finger PLATZ PF04640.14 EGO56631.1 - 1.6 9.4 5.9 0.62 10.7 1.2 2.3 2 1 0 2 2 2 0 PLATZ transcription factor La_HTH_kDCL PF18177.1 EGO56636.1 - 0.095 13.0 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain COesterase PF00135.28 EGO56637.1 - 8.1e-77 259.2 0.0 1e-76 258.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO56637.1 - 7.4e-06 26.0 0.5 4.7e-05 23.3 0.5 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DASH_Dad2 PF08654.10 EGO56639.1 - 9.1e-32 109.4 0.9 1.4e-31 108.8 0.9 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 Shugoshin_N PF07558.11 EGO56640.1 - 5.4e-19 67.8 2.9 1.1e-18 66.8 2.9 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 EGO56640.1 - 1.8e-10 40.4 5.4 1.8e-10 40.4 5.4 3.5 4 0 0 4 4 4 1 Shugoshin C terminus Cpn60_TCP1 PF00118.24 EGO56641.1 - 1.3e-172 574.8 0.7 1.5e-172 574.7 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 EGO56641.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 BRK domain Hist_deacetyl PF00850.19 EGO56641.1 - 0.18 11.2 0.0 0.37 10.2 0.0 1.5 1 0 0 1 1 1 0 Histone deacetylase domain DUF1168 PF06658.12 EGO56642.1 - 8.1e-35 119.6 17.2 8.1e-35 119.6 17.2 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1168) Med19 PF10278.9 EGO56642.1 - 2.6 7.9 11.3 0.04 13.8 3.7 1.8 2 1 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 His_Phos_1 PF00300.22 EGO56643.1 - 1.4e-27 96.7 0.0 2.6e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 EGO56643.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) SKG6 PF08693.10 EGO56644.1 - 3.4e-07 29.5 6.5 3.4e-07 29.5 6.5 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 EGO56644.1 - 7.7e-05 22.6 0.0 7.7e-05 22.6 0.0 3.2 1 1 1 2 2 2 1 TMEM154 protein family CcmD PF04995.14 EGO56644.1 - 0.0076 16.3 2.6 0.013 15.6 2.6 1.3 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) CD34_antigen PF06365.12 EGO56644.1 - 0.052 13.1 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family PAP_PilO PF06864.12 EGO56644.1 - 0.072 11.9 0.0 0.072 11.9 0.0 1.9 2 0 0 2 2 2 0 Pilin accessory protein (PilO) Phage_holin_2_4 PF16082.5 EGO56644.1 - 0.86 9.4 5.9 0.068 12.9 0.7 1.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Ank_2 PF12796.7 EGO56645.1 - 6.1e-37 126.1 4.6 3.1e-10 40.5 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO56645.1 - 5.5e-28 97.0 5.8 1.3e-08 35.2 0.0 5.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO56645.1 - 2.3e-17 61.3 1.8 0.00014 22.0 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EGO56645.1 - 3.6e-14 52.6 5.1 0.00044 20.5 0.1 6.2 1 1 5 6 6 6 5 Ankyrin repeats (many copies) SPX PF03105.19 EGO56645.1 - 5.5e-14 52.9 9.3 1.9e-09 37.9 1.5 2.7 2 1 1 3 3 3 2 SPX domain Ank PF00023.30 EGO56645.1 - 1.8e-12 47.1 8.6 0.00039 20.7 0.0 6.6 7 1 1 8 8 8 3 Ankyrin repeat GDPD PF03009.17 EGO56645.1 - 1.8e-11 44.3 0.1 3.5e-10 40.1 0.0 2.7 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family CUE PF02845.16 EGO56646.1 - 1e-12 47.5 0.0 1.9e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain Snf7 PF03357.21 EGO56647.1 - 9.2e-38 129.5 9.0 1e-37 129.4 9.0 1.0 1 0 0 1 1 1 1 Snf7 Cytadhesin_P30 PF07271.11 EGO56647.1 - 0.062 12.9 1.6 0.077 12.6 1.6 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 V-SNARE_C PF12352.8 EGO56647.1 - 0.64 10.3 4.8 17 5.8 0.0 3.1 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF2203 PF09969.9 EGO56647.1 - 3.4 8.4 6.9 2.1 9.1 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2293 PF10056.9 EGO56648.1 - 7.4e-31 106.2 0.3 7.4e-31 106.2 0.3 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) Spt5_N PF11942.8 EGO56648.1 - 0.0038 18.2 4.5 0.016 16.1 4.5 2.1 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal YL1 PF05764.13 EGO56648.1 - 0.17 12.0 7.4 0.39 10.8 7.4 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Dicty_REP PF05086.12 EGO56648.1 - 0.2 9.6 1.4 0.29 9.1 1.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SIR4_SID PF16991.5 EGO56648.1 - 0.24 11.5 0.7 0.42 10.6 0.7 1.4 1 0 0 1 1 1 0 Sir4 SID domain CDC45 PF02724.14 EGO56648.1 - 0.34 9.2 8.2 0.52 8.5 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 EGO56648.1 - 0.38 10.6 6.9 0.96 9.3 6.9 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 EGO56648.1 - 9.1 6.7 11.0 25 5.3 11.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HA2 PF04408.23 EGO56649.1 - 1.4e-17 63.9 0.1 3.7e-17 62.6 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGO56649.1 - 1.1e-13 51.4 0.0 2.5e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGO56649.1 - 3.4e-11 43.5 0.0 7.2e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGO56649.1 - 5e-06 26.8 0.0 1.2e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EGO56649.1 - 0.00023 21.0 0.0 0.00053 19.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EGO56649.1 - 0.0018 18.0 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGO56649.1 - 0.028 14.5 0.1 2.4 8.2 0.0 2.6 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 EGO56649.1 - 0.031 13.4 0.1 0.08 12.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 EGO56649.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 EGO56649.1 - 0.056 13.0 0.1 2 7.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EGO56649.1 - 0.069 12.4 0.1 0.16 11.2 0.1 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 EGO56649.1 - 0.075 13.5 0.5 0.17 12.4 0.5 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGO56649.1 - 0.11 12.8 0.1 0.47 10.8 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EGO56649.1 - 0.11 13.0 0.1 0.56 10.7 0.1 2.3 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 EGO56649.1 - 0.16 11.3 0.0 0.43 9.9 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family P-mevalo_kinase PF04275.14 EGO56650.1 - 0.061 13.3 0.0 0.068 13.1 0.0 1.1 1 0 0 1 1 1 0 Phosphomevalonate kinase Sec16_C PF12931.7 EGO56652.1 - 5.5e-14 52.5 1.1 3e-13 50.1 0.4 2.2 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 WD40 PF00400.32 EGO56652.1 - 5.1e-10 39.8 0.3 0.067 14.1 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat SRA1 PF07304.11 EGO56652.1 - 1.6e-07 31.2 5.3 1.6e-07 31.2 5.3 3.5 2 1 1 3 3 3 1 Steroid receptor RNA activator (SRA1) ANAPC4_WD40 PF12894.7 EGO56652.1 - 0.0016 18.7 0.2 0.46 10.8 0.1 3.4 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 EGO56653.1 - 2.4e-18 65.7 0.0 3.3e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGO56653.1 - 0.0003 20.7 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EGO56653.1 - 0.0012 18.9 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 EGO56653.1 - 0.04 14.0 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 RNA binding motif RRM_5 PF13893.6 EGO56653.1 - 0.05 13.2 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO56653.1 - 0.054 13.4 0.0 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EGO56653.1 - 0.093 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 B12D PF06522.11 EGO56654.1 - 1.2e-06 28.2 0.0 1.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit COX6B PF02297.17 EGO56655.1 - 1.6e-17 63.5 4.3 1.8e-17 63.3 4.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 EGO56655.1 - 0.01 15.8 1.4 0.017 15.1 1.4 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 EGO56655.1 - 0.037 14.0 0.6 0.037 14.0 0.6 1.5 1 1 0 1 1 1 0 APOBEC-like C-terminal domain ketoacyl-synt PF00109.26 EGO56655.1 - 0.15 11.6 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Sde2_N_Ubi PF13019.6 EGO56656.1 - 1.1e-65 220.4 0.4 1.1e-65 220.4 0.4 1.6 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain AF-4 PF05110.13 EGO56656.1 - 0.0098 14.1 4.8 0.015 13.4 4.4 1.4 1 1 0 1 1 1 1 AF-4 proto-oncoprotein Serglycin PF04360.12 EGO56656.1 - 0.092 12.7 3.4 0.087 12.8 0.8 2.0 2 0 0 2 2 2 0 Serglycin DUF2407 PF10302.9 EGO56656.1 - 0.44 11.1 4.8 1.9 9.1 0.8 3.1 3 1 0 3 3 3 0 DUF2407 ubiquitin-like domain S10_plectin PF03501.15 EGO56657.1 - 6.4e-39 131.9 0.1 7.8e-39 131.7 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain DUF5549 PF17703.1 EGO56657.1 - 0.051 13.2 5.8 0.07 12.8 5.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Na_trans_cytopl PF11933.8 EGO56658.1 - 4.4 7.1 7.5 0.32 10.8 0.6 2.0 2 0 0 2 2 2 0 Cytoplasmic domain of voltage-gated Na+ ion channel HLH PF00010.26 EGO56659.1 - 1.8e-07 31.0 0.0 6.2e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TMEM135_C_rich PF15982.5 EGO56660.1 - 8e-06 26.5 0.4 4.4e-05 24.1 0.4 2.2 1 1 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 GET2 PF08690.10 EGO56661.1 - 1.7e-39 136.3 0.0 4.2e-39 135.1 0.0 1.5 1 1 0 1 1 1 1 GET complex subunit GET2 RseC_MucC PF04246.12 EGO56661.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF2417 PF10329.9 EGO56662.1 - 0.068 12.6 3.5 0.86 9.0 0.1 2.4 1 1 1 2 2 2 0 Region of unknown function (DUF2417) DUF2207 PF09972.9 EGO56662.1 - 0.11 11.2 0.3 0.36 9.5 0.1 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF202 PF02656.15 EGO56662.1 - 1.6 9.2 8.4 3.1 8.3 0.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Coa1 PF08695.10 EGO56663.1 - 4.9e-44 148.8 0.0 6.1e-44 148.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 NFACT-R_1 PF05670.13 EGO56664.1 - 1.1e-36 125.8 0.0 1.9e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain PITH PF06201.13 EGO56665.1 - 3.3e-43 147.5 0.0 4e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 PITH domain Rrn6 PF10214.9 EGO56666.1 - 8.4e-165 550.6 6.9 1.2e-164 550.1 6.9 1.2 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.12 EGO56667.1 - 6.1e-26 90.4 0.0 1.7e-25 89.0 0.0 1.8 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Tup_N PF08581.10 EGO56667.1 - 0.25 11.7 11.3 4 7.8 2.2 2.5 1 1 1 2 2 2 0 Tup N-terminal Atg14 PF10186.9 EGO56667.1 - 0.35 9.9 10.4 0.53 9.3 10.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 EGO56667.1 - 0.8 9.8 6.8 11 6.1 2.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EGO56667.1 - 2.1 7.6 16.5 3 7.1 16.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 EGO56667.1 - 7.2 5.8 9.6 10 5.3 9.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein MOZART1 PF12554.8 EGO56668.1 - 1.4e-19 69.6 0.4 2.8e-19 68.6 0.4 1.5 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated zinc_ribbon_6 PF14599.6 EGO56669.1 - 2.2e-25 88.4 1.2 2.2e-25 88.4 1.2 4.2 2 1 2 4 4 2 1 Zinc-ribbon zf-CHY PF05495.12 EGO56669.1 - 3e-20 72.5 19.7 3e-20 72.5 19.7 3.6 2 1 1 3 3 2 1 CHY zinc finger zf-RING_2 PF13639.6 EGO56669.1 - 1.4e-07 31.7 8.7 1.4e-07 31.7 8.7 5.3 2 1 3 5 5 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EGO56669.1 - 5.1e-06 26.4 6.4 5.1e-06 26.4 6.4 3.5 6 0 0 6 6 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGO56669.1 - 2.1e-05 24.2 6.6 2.1e-05 24.2 6.6 4.4 5 1 1 6 6 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGO56669.1 - 0.0077 16.4 5.9 0.0077 16.4 5.9 4.1 5 1 0 5 5 3 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EGO56669.1 - 0.12 12.1 6.8 0.5 10.2 3.5 3.6 3 0 0 3 3 3 0 RING-like zinc finger TFIIA PF03153.13 EGO56669.1 - 0.13 12.2 16.3 0.1 12.5 1.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.8 EGO56669.1 - 0.36 11.1 8.2 0.96 9.6 8.2 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sigma70_ner PF04546.13 EGO56669.1 - 5.8 6.7 14.5 14 5.5 14.5 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.12 EGO56669.1 - 6.1 6.2 8.3 11 5.3 8.3 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EGO56669.1 - 8.6 4.4 10.6 13 3.8 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family HECT PF00632.25 EGO56671.1 - 9.4e-79 265.1 0.0 1.3e-78 264.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IMS PF00817.20 EGO56672.1 - 4.8e-30 104.5 0.0 7.6e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EGO56672.1 - 1.2e-08 35.6 0.0 3.9e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EGO56672.1 - 4.4e-05 23.6 0.0 0.00013 22.1 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif HHH PF00633.23 EGO56672.1 - 0.0012 18.6 0.0 0.038 13.9 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif tRNA_anti-like PF12869.7 EGO56672.1 - 0.0062 16.2 0.2 0.011 15.3 0.2 1.3 1 0 0 1 1 1 1 tRNA_anti-like WD40 PF00400.32 EGO56673.1 - 3.9e-11 43.3 1.0 0.013 16.3 0.0 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO56673.1 - 0.00012 22.3 0.1 24 5.3 0.0 5.4 3 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGO56673.1 - 0.0016 17.9 0.5 0.02 14.2 0.1 2.6 3 0 0 3 3 3 1 WD40-like domain DUF5536 PF17688.1 EGO56674.1 - 0.24 11.3 4.1 0.39 10.6 2.9 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5536) Med9 PF07544.13 EGO56674.1 - 5.9 7.1 10.3 32 4.7 0.1 3.8 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 BCDHK_Adom3 PF10436.9 EGO56677.1 - 7.6e-77 256.7 0.0 1.1e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGO56677.1 - 5.7e-13 49.4 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGO56677.1 - 0.06 13.2 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyridoxal_deC PF00282.19 EGO56678.1 - 1.5e-18 66.7 0.0 2.4e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGO56678.1 - 4.9e-06 25.7 0.0 8.9e-06 24.9 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGO56678.1 - 0.00025 20.5 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1775 PF07987.11 EGO56678.1 - 0.074 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unkown function (DUF1775) Glyco_transf_34 PF05637.12 EGO56679.1 - 4e-83 278.8 0.0 4.9e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 EGO56679.1 - 0.08 12.5 0.0 3.6 7.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF273 RINGv PF12906.7 EGO56680.1 - 7.1e-10 38.9 5.2 1.2e-09 38.1 1.4 2.3 2 0 0 2 2 2 1 RING-variant domain PHD_4 PF16866.5 EGO56680.1 - 0.015 15.4 5.1 0.38 10.9 1.7 2.4 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 EGO56680.1 - 0.055 13.8 6.7 0.087 13.2 2.1 2.3 2 0 0 2 2 2 0 Ring finger domain PHD PF00628.29 EGO56680.1 - 0.29 11.1 4.9 0.17 11.8 2.3 1.9 2 0 0 2 2 2 0 PHD-finger Proteasome PF00227.26 EGO56681.1 - 1.3e-57 194.4 0.0 4e-33 114.5 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EGO56681.1 - 1.3e-10 40.8 0.3 3.2e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RCC1_2 PF13540.6 EGO56682.1 - 1.5e-12 46.9 6.1 5e-07 29.4 0.2 3.9 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EGO56682.1 - 9.6e-12 45.3 0.8 0.0027 18.3 0.2 3.6 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat NUMOD1 PF07453.13 EGO56682.1 - 0.091 13.1 0.3 4.2 7.7 0.0 2.7 2 0 0 2 2 2 0 NUMOD1 domain Ribonuclease_3 PF00636.26 EGO56683.1 - 1.9e-32 112.0 0.0 6.9e-18 65.2 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGO56683.1 - 9.1e-25 87.3 0.0 1.1e-11 45.0 0.0 3.7 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 EGO56683.1 - 2.6e-19 69.1 0.1 8.9e-19 67.5 0.1 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 EGO56683.1 - 1.1e-17 64.4 0.0 3.4e-17 62.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO56683.1 - 3.3e-08 33.5 0.0 7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 EGO56683.1 - 0.00057 19.5 0.4 0.019 14.6 0.2 2.4 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 EGO56683.1 - 0.003 17.6 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RFC1 PF08519.12 EGO56684.1 - 1.1e-59 201.1 0.0 2.3e-59 200.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EGO56684.1 - 1.7e-14 54.0 0.0 5.3e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EGO56684.1 - 9.7e-09 35.7 0.0 2.7e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGO56684.1 - 6.9e-08 32.6 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 EGO56684.1 - 0.00057 19.7 0.1 0.0064 16.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 EGO56684.1 - 0.0014 18.4 0.0 0.0042 16.9 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_18 PF13238.6 EGO56684.1 - 0.0019 18.8 0.1 0.0068 16.9 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGO56684.1 - 0.0019 18.5 0.0 0.01 16.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO56684.1 - 0.0036 17.7 0.1 0.033 14.6 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EGO56684.1 - 0.017 15.3 0.0 0.058 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGO56684.1 - 0.021 15.0 2.1 0.046 14.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGO56684.1 - 0.028 14.5 0.0 0.074 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EGO56684.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 EGO56684.1 - 0.077 12.9 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 EGO56684.1 - 0.15 12.0 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Ribosomal_L16 PF00252.18 EGO56685.1 - 4e-33 114.2 0.4 5.6e-33 113.8 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Sigma70_r2 PF04542.14 EGO56685.1 - 0.099 12.4 0.0 0.32 10.8 0.0 1.9 1 0 0 1 1 1 0 Sigma-70 region 2 baeRF_family5 PF18846.1 EGO56685.1 - 0.2 11.9 0.1 0.43 10.8 0.1 1.6 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 DNA_pol3_delta2 PF13177.6 EGO56686.1 - 1.2e-11 44.7 0.0 2.5e-11 43.7 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EGO56686.1 - 1.4e-06 28.8 0.0 2.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO56686.1 - 2e-05 24.9 0.2 0.00044 20.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGO56686.1 - 8.2e-05 23.1 1.3 0.0056 17.1 0.6 3.0 2 1 0 2 2 2 1 AAA ATPase domain Rep_fac_C PF08542.11 EGO56686.1 - 0.0012 19.2 0.4 0.0049 17.2 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_24 PF13479.6 EGO56686.1 - 0.0018 18.0 0.3 0.0057 16.4 0.3 1.8 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 EGO56686.1 - 0.0027 17.5 0.1 0.0047 16.7 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EGO56686.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 EGO56686.1 - 0.052 14.1 0.0 0.11 13.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 EGO56686.1 - 0.076 12.4 0.2 1.5 8.2 0.0 2.4 3 0 0 3 3 3 0 Bacterial TniB protein T4SS-DNA_transf PF02534.14 EGO56686.1 - 0.077 11.8 0.1 0.17 10.6 0.0 1.5 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer ER_lumen_recept PF00810.18 EGO56687.1 - 6e-52 176.4 13.3 6e-52 176.4 13.3 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EGO56687.1 - 0.012 15.3 7.4 0.69 9.7 0.3 3.5 2 1 0 3 3 3 0 PQ loop repeat NmrA PF05368.13 EGO56687.1 - 0.023 14.3 0.1 0.032 13.8 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Gly-zipper_Omp PF13488.6 EGO56689.1 - 0.0033 17.4 5.7 0.052 13.6 0.0 2.9 3 0 0 3 3 3 2 Glycine zipper Rick_17kDa_Anti PF05433.15 EGO56689.1 - 0.038 13.9 0.1 0.038 13.9 0.1 3.0 3 0 0 3 3 3 0 Glycine zipper 2TM domain DUF1043 PF06295.12 EGO56689.1 - 0.095 12.7 0.2 0.79 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Rgp1 PF08737.10 EGO56690.1 - 1.9e-167 557.7 1.2 2.3e-167 557.4 0.0 1.7 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.29 EGO56690.1 - 0.0034 17.5 0.0 0.0093 16.0 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EGO56690.1 - 0.0072 16.8 0.1 0.34 11.4 0.0 2.9 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.11 EGO56690.1 - 0.049 13.2 0.0 3 7.3 0.0 2.3 2 0 0 2 2 2 0 SpoOM protein SLX9 PF15341.6 EGO56690.1 - 0.11 12.9 5.9 0.28 11.6 5.9 1.6 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF4129 PF13559.6 EGO56691.1 - 8.4e-08 32.4 0.1 4.7e-07 30.0 0.1 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) NICE-3 PF07406.11 EGO56691.1 - 0.00011 22.3 0.2 0.02 14.9 0.0 2.5 2 0 0 2 2 2 1 NICE-3 protein C_Hendra PF16821.5 EGO56691.1 - 0.045 13.6 1.3 0.2 11.6 1.3 2.1 1 0 0 1 1 1 0 C protein from hendra and measles viruses Herpes_LMP1 PF05297.11 EGO56691.1 - 0.17 11.1 0.0 0.38 9.9 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2427 PF10348.9 EGO56691.1 - 0.57 10.0 6.9 1.1 9.1 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Spore_III_AB PF09548.10 EGO56691.1 - 2.8 8.0 5.5 5.3 7.1 3.3 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DivIC PF04977.15 EGO56691.1 - 8 6.3 6.5 1.5 8.7 1.0 2.7 2 0 0 2 2 2 0 Septum formation initiator Ndc1_Nup PF09531.10 EGO56692.1 - 1.1e-182 609.0 0.2 1.2e-182 608.9 0.2 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.6 EGO56693.1 - 7.1e-28 96.9 4.5 6.6e-27 93.8 0.5 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EGO56693.1 - 2.5e-17 62.6 0.4 6.3e-17 61.3 0.4 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EGO56693.1 - 4.6e-06 26.4 5.7 9.8e-06 25.4 5.7 1.6 1 1 0 1 1 1 1 Syntaxin T3SSipB PF16535.5 EGO56693.1 - 0.0079 16.7 4.7 0.0096 16.4 1.3 2.2 2 0 0 2 2 2 1 Type III cell invasion protein SipB Prominin PF05478.11 EGO56693.1 - 0.022 12.7 2.4 0.039 11.9 2.4 1.5 1 1 0 1 1 1 0 Prominin KASH_CCD PF14662.6 EGO56693.1 - 0.032 14.1 7.7 0.15 11.9 0.0 2.9 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF948 PF06103.11 EGO56693.1 - 0.042 14.1 1.1 3.9 7.8 0.2 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) T4SS-DNA_transf PF02534.14 EGO56693.1 - 0.046 12.5 0.1 0.056 12.2 0.1 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer MCPsignal PF00015.21 EGO56693.1 - 0.13 12.0 2.7 0.66 9.8 0.4 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF883 PF05957.13 EGO56693.1 - 0.22 12.1 6.2 11 6.8 0.0 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) PAH PF02671.21 EGO56693.1 - 0.93 9.7 0.0 0.93 9.7 0.0 2.9 2 1 1 3 3 3 0 Paired amphipathic helix repeat HIP1_clath_bdg PF16515.5 EGO56693.1 - 2.8 8.6 10.0 2.8 8.6 2.3 3.0 2 2 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF16 PF01519.16 EGO56693.1 - 4.3 7.9 7.8 0.56 10.7 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 60KD_IMP PF02096.20 EGO56694.1 - 7.2e-07 29.3 0.0 2.6e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 60Kd inner membrane protein ALG11_N PF15924.5 EGO56695.1 - 2.3e-84 282.7 0.0 3e-84 282.2 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EGO56695.1 - 3.6e-25 88.5 0.0 5.5e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGO56695.1 - 1.3e-13 51.6 0.0 3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGO56695.1 - 0.00057 19.9 0.0 0.0013 18.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Gag_p12 PF01141.18 EGO56695.1 - 0.13 12.6 0.0 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 tRNA_U5-meth_tr PF05958.11 EGO56696.1 - 2.8e-08 33.1 0.0 4.7e-07 29.1 0.0 2.6 3 1 0 3 3 3 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 EGO56696.1 - 0.00021 21.1 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGO56696.1 - 0.00021 20.8 0.0 0.00046 19.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGO56696.1 - 0.0022 18.7 0.0 0.0068 17.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGO56696.1 - 0.023 14.4 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltrans_SAM PF10672.9 EGO56696.1 - 0.087 12.0 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase TRM PF02005.16 EGO56696.1 - 0.1 11.8 0.1 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase PCO_ADO PF07847.12 EGO56696.1 - 0.11 12.0 0.2 0.33 10.4 0.1 1.8 2 0 0 2 2 2 0 PCO_ADO Glyco_hydro_72 PF03198.14 EGO56697.1 - 5.2e-117 390.6 5.1 6.5e-117 390.3 5.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EGO56697.1 - 0.00069 19.1 0.2 0.003 17.0 0.2 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) WLM PF08325.10 EGO56698.1 - 4.7e-57 193.1 0.0 7.9e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 EGO56698.1 - 0.00018 21.6 0.6 0.00042 20.4 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.9 EGO56698.1 - 0.03 14.2 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Citrate_bind PF16114.5 EGO56699.1 - 4e-86 287.0 0.0 5.4e-86 286.6 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 EGO56699.1 - 9.4e-08 31.9 0.0 1.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 EGO56699.1 - 0.0063 14.7 0.0 0.0095 14.1 0.0 1.1 1 0 0 1 1 1 1 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Citrate_synt PF00285.21 EGO56701.1 - 1.8e-21 76.6 0.0 2.9e-18 66.1 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 EGO56701.1 - 4.9e-19 68.8 0.1 1.6e-18 67.2 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EGO56701.1 - 3.2e-15 56.2 0.1 5.5e-15 55.5 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EGO56701.1 - 2e-05 24.4 0.0 0.00051 19.8 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Ribosomal_L30 PF00327.20 EGO56702.1 - 8e-17 60.9 0.1 1.6e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MRG PF05712.13 EGO56703.1 - 1.4e-61 207.3 1.1 1.9e-61 206.8 1.1 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EGO56704.1 - 1.5e-07 31.2 0.4 2.9e-07 30.3 0.4 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 EGO56704.1 - 0.0032 17.3 1.5 0.0055 16.6 1.5 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cnl2_NKP2 PF09447.10 EGO56705.1 - 1.2e-27 95.9 1.1 1.9e-27 95.2 1.1 1.4 1 0 0 1 1 1 1 Cnl2/NKP2 family protein SIKE PF05769.11 EGO56705.1 - 0.017 15.1 1.7 0.026 14.4 0.8 1.6 2 0 0 2 2 2 0 SIKE family CENP-Q PF13094.6 EGO56707.1 - 5.7e-53 179.6 0.7 5.7e-53 179.6 0.7 2.7 3 1 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit CENP-F_leu_zip PF10473.9 EGO56707.1 - 0.05 13.6 3.7 0.82 9.7 1.1 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSNAXIP1_N PF15739.5 EGO56707.1 - 0.09 13.2 0.6 0.27 11.6 0.6 1.8 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus LicD PF04991.13 EGO56708.1 - 4.5e-25 89.1 0.1 2.6e-18 67.0 0.4 2.2 1 1 1 2 2 2 2 LicD family Etmic-2 PF06670.11 EGO56708.1 - 0.15 11.0 2.0 0.22 10.4 2.0 1.1 1 0 0 1 1 1 0 Microneme protein Etmic-2 TCRP1 PF14944.6 EGO56711.1 - 0.0064 16.5 0.3 0.0068 16.4 0.3 1.0 1 0 0 1 1 1 1 Tongue Cancer Chemotherapy Resistant Protein 1 Fungal_trans PF04082.18 EGO56713.1 - 4e-24 85.1 0.0 6.5e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO56713.1 - 1.6e-07 31.3 13.7 2.9e-07 30.5 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Shugoshin_N PF07558.11 EGO56713.1 - 0.03 14.2 0.7 0.062 13.2 0.7 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Tmemb_cc2 PF10267.9 EGO56713.1 - 0.38 9.8 3.8 0.57 9.3 3.8 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Abhydrolase_3 PF07859.13 EGO56715.1 - 9.8e-05 22.3 0.5 0.00026 20.9 0.1 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO56715.1 - 0.00037 21.2 0.2 0.00057 20.5 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO56715.1 - 0.003 17.3 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO56715.1 - 0.018 14.5 0.0 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.20 EGO56715.1 - 0.047 13.8 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.8 EGO56715.1 - 0.054 12.8 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EGO56715.1 - 0.085 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Pyridoxal_deC PF00282.19 EGO56717.1 - 3.7e-77 259.6 0.0 5.5e-77 259.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain FAD_binding_3 PF01494.19 EGO56719.1 - 1.6e-73 248.0 0.0 2.1e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGO56719.1 - 3.5e-43 147.5 0.0 6.9e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.27 EGO56719.1 - 0.0015 19.1 0.0 0.0048 17.4 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO56719.1 - 0.0015 17.8 0.0 0.01 15.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO56719.1 - 0.0042 16.7 0.0 0.025 14.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO56719.1 - 0.013 15.7 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 EGO56719.1 - 0.023 14.2 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 EGO56719.1 - 0.049 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain HI0933_like PF03486.14 EGO56719.1 - 0.056 12.1 0.0 0.091 11.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 EGO56719.1 - 0.079 12.0 0.0 0.21 10.6 0.0 1.7 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EGO56719.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 EGO56719.1 - 0.13 12.6 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain HET PF06985.11 EGO56720.1 - 3.1e-26 92.5 0.5 5.2e-26 91.7 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_3 PF07859.13 EGO56722.1 - 5e-32 111.5 0.0 4e-22 79.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.25 EGO56722.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Say1_Mug180 PF10340.9 EGO56722.1 - 0.075 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase EphA2_TM PF14575.6 EGO56723.1 - 0.022 15.7 0.0 0.16 12.8 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DDHD PF02862.17 EGO56724.1 - 3.5e-26 92.7 0.0 1.2e-25 91.0 0.0 1.9 1 1 0 1 1 1 1 DDHD domain Abhydrolase_6 PF12697.7 EGO56724.1 - 0.068 13.8 0.2 0.27 11.8 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EGO56724.1 - 0.24 10.9 0.0 0.47 10.0 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase zf-RING_2 PF13639.6 EGO56726.1 - 2.6e-15 56.4 16.5 4.7e-14 52.4 6.1 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.6 EGO56726.1 - 1e-09 38.1 12.1 2.9e-07 30.2 3.9 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGO56726.1 - 9.3e-09 34.9 2.0 9.3e-09 34.9 2.0 2.6 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGO56726.1 - 1.5e-08 34.3 18.0 2.2e-08 33.8 7.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO56726.1 - 3.4e-07 30.0 12.1 1.2e-05 25.1 4.4 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGO56726.1 - 1.4e-06 28.1 15.1 1.4e-05 24.9 5.3 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO56726.1 - 6.6e-06 26.0 4.1 6.6e-06 26.0 4.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGO56726.1 - 6.7e-06 26.3 8.6 6.7e-06 26.3 8.6 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGO56726.1 - 0.00094 19.2 4.1 0.00094 19.2 4.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger HypA PF01155.19 EGO56726.1 - 0.0018 18.3 1.4 0.0018 18.3 1.4 2.3 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ANAPC11 PF12861.7 EGO56726.1 - 0.0034 17.4 3.2 0.0034 17.4 3.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Cytochrom_CIII PF02085.16 EGO56726.1 - 0.032 14.6 2.0 0.032 14.6 2.0 2.7 2 1 0 2 2 1 0 Class III cytochrome C family zf-RING_4 PF14570.6 EGO56726.1 - 0.7 9.7 13.9 1.2 8.9 2.7 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 EGO56726.1 - 1.1 9.4 13.1 0.27 11.3 2.2 2.9 2 1 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 EGO56726.1 - 1.4 9.0 14.7 0.39 10.7 3.0 2.5 2 0 0 2 2 2 0 zinc-ribbons zinc_ribbon_9 PF14369.6 EGO56726.1 - 1.7 8.9 9.1 2.3 8.6 3.9 2.7 2 0 0 2 2 2 0 zinc-ribbon PHD PF00628.29 EGO56726.1 - 1.9 8.5 14.2 2.4 8.1 2.1 2.7 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 EGO56726.1 - 2.9 7.9 9.9 9 6.3 0.4 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 EGO56726.1 - 4 7.1 14.8 0.41 10.3 4.6 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type HET PF06985.11 EGO56727.1 - 4.3e-10 40.1 0.0 4.3e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UNC45-central PF11701.8 EGO56729.1 - 1.9e-57 193.5 0.8 1.7e-56 190.4 0.1 2.8 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central IFRD PF05004.13 EGO56729.1 - 0.0039 16.3 0.9 1.2 8.2 0.0 2.8 2 1 0 2 2 2 2 Interferon-related developmental regulator (IFRD) LD_cluster3 PF18180.1 EGO56729.1 - 0.022 14.4 0.0 6.1 6.4 0.0 2.4 2 0 0 2 2 2 0 SLOG cluster3 family V-ATPase_H_N PF03224.14 EGO56729.1 - 0.038 13.3 1.4 18 4.5 0.1 3.9 3 2 1 4 4 4 0 V-ATPase subunit H HEAT_EZ PF13513.6 EGO56729.1 - 0.061 13.9 5.7 5 7.7 0.0 4.8 5 0 0 5 5 5 0 HEAT-like repeat HEAT PF02985.22 EGO56729.1 - 0.093 13.0 7.4 3.2 8.3 0.0 5.1 6 0 0 6 6 6 0 HEAT repeat HEAT_2 PF13646.6 EGO56729.1 - 0.17 12.3 11.9 6.2 7.3 2.1 5.6 4 1 2 6 6 6 0 HEAT repeats Z1 PF10593.9 EGO56731.1 - 0.063 12.8 0.3 0.097 12.2 0.3 1.2 1 0 0 1 1 1 0 Z1 domain zf-DNL PF05180.12 EGO56731.1 - 0.35 10.8 2.0 0.73 9.8 2.0 1.5 1 0 0 1 1 1 0 DNL zinc finger CDC45 PF02724.14 EGO56732.1 - 0.075 11.3 2.7 0.12 10.7 2.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 EGO56732.1 - 0.28 9.2 7.7 0.045 11.9 4.2 1.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Zip PF02535.22 EGO56732.1 - 1.3 8.2 2.4 1.3 8.2 2.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter WRNPLPNID PF15017.6 EGO56732.1 - 2.3 9.1 10.2 4.7 8.2 10.2 1.5 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box PBP1_TM PF14812.6 EGO56732.1 - 2.4 8.6 9.5 22 5.5 9.5 2.4 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 EGO56732.1 - 5.9 6.5 14.1 10 5.8 14.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 EGO56732.1 - 9.5 6.7 15.8 25 5.3 15.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CorA PF01544.18 EGO56733.1 - 0.0022 17.4 4.0 0.0057 16.0 4.0 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ERCC4 PF02732.15 EGO56734.1 - 1e-24 87.5 0.3 1e-24 87.5 0.3 1.5 2 0 0 2 2 2 1 ERCC4 domain DUF1682 PF07946.14 EGO56734.1 - 1.9 7.6 19.1 6.8 5.8 18.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Kinesin PF00225.23 EGO56737.1 - 5.5e-90 301.7 4.0 2.5e-89 299.5 0.0 3.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EGO56737.1 - 5.9e-19 68.5 0.0 3.4e-15 56.3 0.0 3.6 2 1 1 3 3 3 2 Microtubule binding Reprolysin_5 PF13688.6 EGO56738.1 - 6e-59 199.5 3.0 6e-59 199.5 3.0 2.5 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EGO56738.1 - 7.5e-50 169.4 0.4 1.5e-49 168.4 0.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EGO56738.1 - 8.2e-48 162.9 1.0 1.5e-47 162.0 1.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EGO56738.1 - 2.7e-16 60.1 32.4 2.7e-16 60.1 32.4 4.6 4 1 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 EGO56738.1 - 6.5e-11 42.8 0.0 1.4e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 EGO56738.1 - 0.0091 16.5 10.4 0.0091 16.5 10.4 4.4 2 1 2 4 4 4 1 ADAM cysteine-rich domain Comm PF15957.5 EGO56738.1 - 0.081 13.3 0.1 0.26 11.7 0.0 1.8 2 0 0 2 2 2 0 Commissureless AMP-binding PF00501.28 EGO56739.1 - 3.7e-87 292.7 0.2 4.5e-87 292.4 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO56739.1 - 1.1e-25 90.4 0.8 8.8e-24 84.3 0.5 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGO56739.1 - 3.3e-18 65.3 0.6 9.3e-18 63.9 0.6 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus UvrD-helicase PF00580.21 EGO56740.1 - 1.8e-13 50.7 1.9 1.6e-08 34.5 0.0 2.9 1 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EGO56740.1 - 3.3e-12 47.0 0.0 6.2e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EGO56740.1 - 1.3e-08 34.6 0.0 2.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EGO56740.1 - 6e-05 22.9 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 EGO56740.1 - 0.00015 21.2 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EGO56740.1 - 0.00021 21.1 0.0 1.2 8.9 0.0 3.3 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EGO56740.1 - 0.0019 18.5 0.0 0.005 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EGO56740.1 - 0.0038 16.9 0.0 0.0089 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EGO56740.1 - 0.0048 16.7 0.0 0.0098 15.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Arabino_trans_N PF17689.1 EGO56740.1 - 0.041 14.1 0.0 0.075 13.2 0.0 1.4 1 0 0 1 1 1 0 Arabinosyltransferase concanavalin like domain AAA_16 PF13191.6 EGO56740.1 - 0.041 14.3 0.2 0.15 12.5 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 EGO56740.1 - 0.12 11.6 0.0 0.4 9.9 0.0 1.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PDDEXK_3 PF13366.6 EGO56740.1 - 0.12 12.7 0.0 0.36 11.2 0.0 1.8 2 0 0 2 2 1 0 PD-(D/E)XK nuclease superfamily Zeta_toxin PF06414.12 EGO56740.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Pkinase_fungal PF17667.1 EGO56741.1 - 1e-125 419.8 0.0 1.3e-125 419.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGO56741.1 - 6.2e-08 32.3 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO56741.1 - 0.016 14.5 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.23 EGO56741.1 - 0.049 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family SOG2 PF10428.9 EGO56741.1 - 0.065 12.4 7.4 0.098 11.8 7.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Pex14_N PF04695.13 EGO56741.1 - 0.57 10.8 7.3 1.1 9.9 7.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Totivirus_coat PF05518.11 EGO56741.1 - 2.1 6.3 4.7 2.8 5.9 4.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein WD40 PF00400.32 EGO56744.1 - 4.2e-09 36.9 8.1 0.045 14.6 0.0 6.6 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO56744.1 - 4.6e-08 33.3 0.8 0.032 14.5 0.1 3.8 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGO56744.1 - 0.0001 22.3 0.0 6.4 6.6 0.0 3.5 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 EGO56744.1 - 0.021 13.6 0.0 0.078 11.7 0.0 1.9 2 0 0 2 2 2 0 Nup133 N terminal like Macoilin PF09726.9 EGO56744.1 - 0.52 8.8 4.9 0.66 8.5 4.9 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 EGO56744.1 - 1.3 8.1 11.4 1.8 7.7 11.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1751 PF08551.10 EGO56745.1 - 4.1e-30 104.3 4.1 9.5e-30 103.1 4.1 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EGO56745.1 - 0.52 10.3 11.4 1.9 8.4 10.0 2.0 2 0 0 2 2 2 0 Rhomboid family TPR_1 PF00515.28 EGO56749.1 - 6.3e-59 193.6 27.6 6.5e-08 32.1 0.0 11.0 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 EGO56749.1 - 6.6e-52 169.5 21.4 1.1e-06 28.2 0.0 10.5 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 EGO56749.1 - 6.4e-39 128.9 17.4 1.1e-06 28.3 0.0 10.7 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 EGO56749.1 - 1.8e-31 108.5 11.7 2e-07 31.6 0.0 6.8 4 1 1 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 EGO56749.1 - 3.2e-30 104.2 14.4 1e-06 28.9 0.0 7.2 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGO56749.1 - 2.5e-29 99.5 13.2 1.5e-05 25.4 0.0 9.2 3 2 6 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.6 EGO56749.1 - 3.3e-29 99.1 17.2 0.0025 18.1 0.0 10.4 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.6 EGO56749.1 - 3.4e-27 93.9 29.9 6.1e-06 25.8 0.3 9.8 5 2 4 9 9 9 6 TPR repeat TPR_19 PF14559.6 EGO56749.1 - 1.4e-25 89.6 20.1 0.00013 22.4 0.2 6.1 4 1 3 7 7 7 7 Tetratricopeptide repeat TPR_6 PF13174.6 EGO56749.1 - 1.6e-23 81.7 12.3 0.00064 20.2 0.0 9.3 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 EGO56749.1 - 3.3e-19 68.8 14.1 0.0021 18.2 0.3 7.3 3 2 6 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.6 EGO56749.1 - 4.9e-17 60.6 12.8 0.01 15.8 0.1 9.6 10 1 0 10 10 9 4 Tetratricopeptide repeat TPR_15 PF13429.6 EGO56749.1 - 9.2e-12 44.8 7.2 0.00011 21.5 1.2 4.8 1 1 2 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO56749.1 - 1.7e-11 44.2 15.0 4.3e-06 26.8 3.8 3.6 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 EGO56749.1 - 7.8e-07 29.0 5.9 0.073 12.8 0.0 5.1 4 2 1 5 5 5 1 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 EGO56749.1 - 3.4e-05 23.6 18.6 2.4 8.1 0.1 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGO56749.1 - 0.00069 19.6 5.9 1.1 9.3 0.0 5.1 6 0 0 6 6 5 1 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.9 EGO56749.1 - 0.0042 16.8 0.7 8.9 6.0 0.0 3.4 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_20 PF14561.6 EGO56749.1 - 0.019 15.3 10.2 0.17 12.2 0.2 4.2 5 1 1 6 6 4 0 Tetratricopeptide repeat SNAP PF14938.6 EGO56749.1 - 0.055 12.9 13.2 11 5.4 1.9 4.5 2 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP ChAPs PF09295.10 EGO56749.1 - 0.066 12.2 2.2 8 5.3 0.2 2.8 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Asp-B-Hydro_N PF05279.11 EGO56749.1 - 5 7.1 8.6 7.1 6.6 6.3 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region TPR_3 PF07720.12 EGO56749.1 - 9 6.4 21.9 40 4.3 0.1 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Ribosomal_L3 PF00297.22 EGO56750.1 - 7.1e-181 601.1 13.2 8.1e-181 600.9 13.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 NuiA PF07924.11 EGO56751.1 - 0.048 14.0 0.2 0.91 9.9 0.2 2.1 1 1 0 1 1 1 0 Nuclease A inhibitor-like protein adh_short PF00106.25 EGO56752.1 - 4.5e-37 127.4 0.5 6.5e-37 126.9 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO56752.1 - 2.8e-31 108.9 0.1 4.1e-31 108.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO56752.1 - 7.5e-07 29.2 6.7 6.6e-06 26.1 6.7 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO56752.1 - 0.014 14.9 0.1 0.025 14.0 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EGO56752.1 - 0.016 14.6 0.1 0.025 13.9 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) T2SSE_N PF05157.15 EGO56752.1 - 0.16 12.2 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain Sugar_tr PF00083.24 EGO56753.1 - 1.8e-112 376.5 19.7 2.3e-112 376.2 19.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO56753.1 - 4.7e-25 88.3 28.1 4.7e-25 88.3 28.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Lig_chan PF00060.26 EGO56753.1 - 1.4 8.8 3.4 2.9 7.7 0.2 2.4 2 0 0 2 2 2 0 Ligand-gated ion channel MFS_1 PF07690.16 EGO56754.1 - 1.6e-37 129.3 42.7 1.6e-37 129.3 42.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO56754.1 - 9.5e-11 41.2 11.2 1.3e-10 40.8 10.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_72 PF03198.14 EGO56756.1 - 9.4e-91 304.3 0.2 1.4e-89 300.4 0.2 2.1 1 1 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 EGO56756.1 - 0.005 16.0 0.1 0.011 14.9 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Apolipoprotein PF01442.18 EGO56759.1 - 1.1e-07 32.0 38.6 1.1e-07 32.0 38.6 3.4 3 1 0 3 3 3 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 EGO56759.1 - 0.0027 17.7 37.3 0.055 13.5 4.6 5.1 2 1 1 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 EGO56759.1 - 0.0044 16.7 16.8 0.0044 16.7 16.8 5.4 3 2 2 5 5 5 2 Intermediate filament protein DASH_Spc34 PF08657.10 EGO56759.1 - 0.12 12.2 0.0 0.12 12.2 0.0 5.1 2 1 1 4 4 3 0 DASH complex subunit Spc34 Csm1_N PF18504.1 EGO56759.1 - 0.18 12.2 0.2 0.18 12.2 0.2 8.2 5 2 2 7 7 6 0 Csm1 N-terminal domain Golgin_A5 PF09787.9 EGO56759.1 - 1.2 8.5 64.6 1.4 8.3 7.0 4.3 3 1 1 4 4 4 0 Golgin subfamily A member 5 Spc7 PF08317.11 EGO56759.1 - 1.6 7.6 69.5 0.0079 15.1 25.5 5.4 2 1 3 5 5 5 0 Spc7 kinetochore protein DUF3915 PF13054.6 EGO56759.1 - 2 8.4 7.1 0.46 10.5 2.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) LPP PF04728.13 EGO56759.1 - 2.1 8.8 23.4 7.2 7.1 0.4 7.2 5 1 1 6 6 6 0 Lipoprotein leucine-zipper Fib_alpha PF08702.10 EGO56759.1 - 3.1 8.0 53.2 0.048 13.9 7.5 4.7 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 EGO56759.1 - 6.7 7.0 83.7 3 8.2 12.9 6.1 3 1 3 6 6 6 0 Outer membrane protein (OmpH-like) FlaC_arch PF05377.11 EGO56759.1 - 7 7.1 30.6 3.8 8.0 0.0 8.3 7 1 2 9 9 9 0 Flagella accessory protein C (FlaC) TIP49 PF06068.13 EGO56760.1 - 1.1e-155 518.1 2.7 1.4e-155 517.8 2.7 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EGO56760.1 - 4.5e-22 78.0 0.1 1.7e-21 76.1 0.1 2.1 2 0 0 2 2 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 EGO56760.1 - 1.2e-08 34.9 0.6 9.5e-06 25.4 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 EGO56760.1 - 3.7e-08 33.9 1.1 5.9e-05 23.5 0.1 2.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 EGO56760.1 - 6e-07 29.1 1.4 1.1e-06 28.2 1.4 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EGO56760.1 - 7.1e-07 29.8 0.1 1.9e-06 28.4 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EGO56760.1 - 0.00075 18.9 0.6 0.015 14.6 0.4 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EGO56760.1 - 0.0014 18.2 0.2 0.003 17.2 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGO56760.1 - 0.0022 18.3 0.0 0.41 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EGO56760.1 - 0.0039 16.9 0.1 2 8.1 0.1 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain ATPase PF06745.13 EGO56760.1 - 0.0089 15.4 1.0 0.019 14.3 1.0 1.5 1 0 0 1 1 1 1 KaiC AAA_28 PF13521.6 EGO56760.1 - 0.012 15.9 0.1 0.025 14.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGO56760.1 - 0.015 15.6 2.2 0.37 11.1 2.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGO56760.1 - 0.018 15.1 0.8 1 9.3 0.1 3.0 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EGO56760.1 - 0.025 14.4 1.6 0.3 10.8 1.6 2.1 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGO56760.1 - 0.033 14.4 0.0 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGO56760.1 - 0.096 12.7 0.6 0.26 11.3 0.1 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 EGO56760.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 GYF PF02213.16 EGO56761.1 - 1.5e-09 37.4 2.0 3.6e-09 36.2 2.0 1.7 1 0 0 1 1 1 1 GYF domain Gluconate_2-dh3 PF13618.6 EGO56761.1 - 3.7 7.8 8.3 0.96 9.7 4.0 2.3 2 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 UFD1 PF03152.14 EGO56762.1 - 2.9e-68 228.7 0.0 3.6e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 LRR_4 PF12799.7 EGO56763.1 - 0.0045 17.4 8.2 0.18 12.3 0.6 4.6 4 2 1 5 5 5 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGO56763.1 - 0.04 13.8 1.1 0.082 12.8 1.1 1.5 1 0 0 1 1 1 0 F-box-like Gly-zipper_Omp PF13488.6 EGO56763.1 - 1 9.4 12.6 2 8.5 12.6 1.4 1 0 0 1 1 1 0 Glycine zipper DUF3176 PF11374.8 EGO56764.1 - 1.1e-19 70.6 2.5 2.5e-19 69.4 2.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) EI24 PF07264.11 EGO56764.1 - 0.033 14.4 0.6 0.084 13.1 0.6 1.6 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Imm_superinfect PF14373.6 EGO56764.1 - 6.3 6.8 5.8 26 4.8 0.7 2.6 2 0 0 2 2 2 0 Superinfection immunity protein DUF1908 PF08926.11 EGO56775.1 - 0.035 13.2 0.4 0.073 12.1 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) DUF4407 PF14362.6 EGO56775.1 - 3.3 7.0 8.6 6.4 6.0 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4757 PF15949.5 EGO56777.1 - 0.019 15.4 0.6 5.6 7.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4757) DUF2956 PF11169.8 EGO56777.1 - 0.17 12.1 0.9 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) RR_TM4-6 PF06459.12 EGO56779.1 - 0.17 11.7 4.5 0.21 11.4 4.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.14 EGO56779.1 - 1.3 8.7 8.3 1.8 8.3 8.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIE-A_C PF11521.8 EGO56779.1 - 7.6 6.9 11.5 2.6 8.4 7.1 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha VEFS-Box PF09733.9 EGO56781.1 - 3.2e-07 30.2 0.5 6.7e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 VEFS-Box of polycomb protein SUIM_assoc PF16619.5 EGO56781.1 - 0.22 11.6 21.3 0.28 11.3 3.3 3.0 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CPSF100_C PF13299.6 EGO56781.1 - 0.36 11.0 2.4 16 5.7 0.4 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Androgen_recep PF02166.16 EGO56781.1 - 1.7 7.4 15.7 1.8 7.3 2.6 2.4 2 0 0 2 2 2 0 Androgen receptor AAA PF00004.29 EGO56782.1 - 2.2e-35 122.0 0.0 4.6e-35 120.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO56782.1 - 5.8e-11 42.0 2.4 6.2e-11 41.9 0.4 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 EGO56782.1 - 6.1e-05 23.5 2.7 0.0017 18.7 0.0 3.5 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EGO56782.1 - 7.1e-05 22.6 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EGO56782.1 - 0.00021 21.1 0.0 0.00065 19.5 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 EGO56782.1 - 0.0016 18.5 0.0 0.01 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGO56782.1 - 0.0032 17.8 2.4 0.037 14.3 0.2 3.6 4 1 0 4 4 3 1 AAA domain AAA_33 PF13671.6 EGO56782.1 - 0.0042 17.3 0.0 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGO56782.1 - 0.017 15.1 0.1 0.05 13.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGO56782.1 - 0.018 15.6 0.0 0.088 13.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EGO56782.1 - 0.021 14.0 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 EGO56782.1 - 0.028 13.8 0.0 0.073 12.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGO56782.1 - 0.04 13.6 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGO56782.1 - 0.064 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TniB PF05621.11 EGO56782.1 - 0.065 12.6 0.0 0.42 10.0 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 EGO56782.1 - 0.099 12.9 0.0 0.44 10.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGO56782.1 - 0.17 11.4 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Hydin_ADK PF17213.3 EGO56782.1 - 1.4 9.2 9.7 7.3 6.8 0.0 3.5 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Mus7 PF09462.10 EGO56783.1 - 2.7e-219 730.1 0.0 3.6e-219 729.7 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family tRNA-synt_His PF13393.6 EGO56783.1 - 0.056 12.7 0.3 0.11 11.7 0.3 1.4 1 0 0 1 1 1 0 Histidyl-tRNA synthetase COX4 PF02936.14 EGO56785.1 - 4.2e-48 162.9 0.4 4.9e-48 162.6 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DAO PF01266.24 EGO56787.1 - 2e-51 175.6 0.0 2.9e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EGO56787.1 - 1.1e-45 154.6 0.2 1.9e-45 153.8 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EGO56787.1 - 5.3e-08 32.4 0.0 1.2e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGO56787.1 - 2.5e-05 23.8 0.1 0.00024 20.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO56787.1 - 2.7e-05 23.6 0.0 4.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO56787.1 - 0.00016 21.0 0.1 0.00037 19.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO56787.1 - 0.0035 17.5 0.2 0.011 16.0 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EGO56787.1 - 0.0049 16.8 0.1 0.0092 15.9 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EGO56787.1 - 0.0056 15.4 0.3 0.0092 14.7 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EGO56787.1 - 0.0061 15.8 0.1 0.014 14.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 EGO56787.1 - 0.0079 15.5 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EGO56787.1 - 0.014 14.5 0.1 0.035 13.2 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EGO56787.1 - 0.025 15.1 0.4 0.066 13.8 0.4 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 EGO56787.1 - 0.2 10.2 0.3 1.3 7.4 0.0 1.9 2 0 0 2 2 2 0 GDP dissociation inhibitor TPT PF03151.16 EGO56788.1 - 1.7e-55 188.4 5.5 2.2e-55 188.1 5.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGO56788.1 - 1.8e-09 37.9 25.8 1.6e-05 25.1 10.7 3.2 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGO56788.1 - 3.9e-07 29.6 7.8 0.0016 17.7 1.2 2.1 2 0 0 2 2 2 2 UAA transporter family PUNUT PF16913.5 EGO56788.1 - 0.00024 20.4 4.0 0.00044 19.6 4.0 1.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport Saf_2TM PF18303.1 EGO56788.1 - 0.19 11.3 0.7 1.6 8.3 0.0 2.6 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain Multi_Drug_Res PF00893.19 EGO56788.1 - 8.7 7.1 8.5 2 9.1 0.8 3.2 4 0 0 4 4 4 0 Small Multidrug Resistance protein DUF382 PF04037.13 EGO56789.1 - 1.4e-60 203.0 1.5 1.4e-60 203.0 1.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 EGO56789.1 - 1.3e-19 69.8 4.4 1.5e-19 69.6 2.0 2.3 2 0 0 2 2 2 1 PSP DUF601 PF04642.12 EGO56791.1 - 0.18 11.3 1.0 0.45 10.0 0.8 1.6 1 1 1 2 2 2 0 Protein of unknown function, DUF601 RGS PF00615.19 EGO56797.1 - 3.3e-11 43.5 0.0 5.4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DMAP_binding PF06464.11 EGO56797.1 - 0.24 12.2 1.3 3.8 8.4 0.4 2.6 2 0 0 2 2 2 0 DMAP1-binding Domain ORC5_C PF14630.6 EGO56798.1 - 9.1e-87 291.2 0.0 1.3e-86 290.7 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EGO56798.1 - 1e-16 61.8 0.1 3.1e-16 60.2 0.0 1.9 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 EGO56798.1 - 0.0017 18.3 0.0 0.004 17.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TniB PF05621.11 EGO56798.1 - 0.0066 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 EGO56798.1 - 0.02 15.2 0.1 0.071 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EGO56799.1 - 3.6e-62 209.8 0.0 5.7e-62 209.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGO56799.1 - 4.5e-23 81.5 0.4 2.5e-22 79.2 0.2 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 EGO56799.1 - 0.0046 17.4 0.0 0.62 10.5 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EGO56799.1 - 0.0087 16.0 0.2 0.028 14.3 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase T3SS_ATPase_C PF18269.1 EGO56799.1 - 0.015 15.2 1.0 0.079 12.8 1.0 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain NB-ARC PF00931.22 EGO56799.1 - 0.02 14.1 0.4 0.094 11.9 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EGO56799.1 - 0.037 13.9 0.0 0.088 12.7 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EGO56799.1 - 0.054 13.4 0.2 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 EGO56799.1 - 0.057 13.8 1.1 0.48 10.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EGO56799.1 - 0.063 12.6 0.3 0.11 11.8 0.3 1.4 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.22 EGO56799.1 - 0.08 13.3 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EGO56799.1 - 0.11 12.9 0.1 0.42 11.0 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain Alpha-amylase_C PF02806.18 EGO56800.1 - 4.8e-26 91.1 0.0 3.5e-25 88.3 0.0 2.4 3 0 0 3 3 3 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EGO56800.1 - 6.2e-19 68.1 0.0 1.9e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EGO56800.1 - 1.2e-15 57.9 0.1 8.3e-12 45.3 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Cellulase PF00150.18 EGO56800.1 - 0.034 13.6 0.0 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) AAA_2 PF07724.14 EGO56801.1 - 8.5e-34 117.1 0.0 2.6e-31 109.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EGO56801.1 - 8.1e-13 48.9 0.0 1.6e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EGO56801.1 - 1.3e-08 34.8 0.0 2.7e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EGO56801.1 - 4.9e-08 33.1 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 EGO56801.1 - 3.6e-05 23.0 0.0 7.9e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain AAA_22 PF13401.6 EGO56801.1 - 0.00016 22.0 0.2 0.0016 18.7 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGO56801.1 - 0.002 17.6 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 EGO56801.1 - 0.0021 18.5 0.0 0.007 16.8 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EGO56801.1 - 0.003 17.6 0.0 0.0065 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO56801.1 - 0.013 16.0 0.0 0.033 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGO56801.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGO56801.1 - 0.046 13.1 0.0 0.98 8.8 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 EGO56801.1 - 0.057 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EGO56801.1 - 0.059 13.9 0.2 0.16 12.5 0.0 1.8 2 0 0 2 2 2 0 ABC transporter ResIII PF04851.15 EGO56801.1 - 0.077 13.0 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TniB PF05621.11 EGO56801.1 - 0.077 12.4 0.1 0.32 10.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 EGO56801.1 - 0.085 12.6 0.0 0.41 10.3 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 EGO56801.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 EGO56801.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGO56801.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.12 EGO56801.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 EGO56801.1 - 0.16 12.3 0.7 0.4 11.0 0.0 2.0 2 1 1 3 3 2 0 AAA domain AAA_25 PF13481.6 EGO56801.1 - 0.17 11.5 0.1 12 5.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 EGO56802.1 - 4.5e-22 77.9 9.9 1.3e-07 32.2 0.0 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO56802.1 - 0.00048 20.4 4.6 1.7 9.0 0.0 4.3 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGO56802.1 - 0.0046 16.1 1.2 0.17 10.9 0.7 2.1 2 0 0 2 2 2 2 Coatomer WD associated region TFIIE-A_C PF11521.8 EGO56802.1 - 0.14 12.4 13.9 0.72 10.2 2.4 3.3 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Transket_pyr PF02779.24 EGO56803.1 - 2.4e-63 213.0 0.0 5.6e-63 211.8 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EGO56803.1 - 5.9e-58 194.9 0.1 1e-57 194.1 0.1 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 EGO56803.1 - 2.3e-57 194.3 0.0 3.1e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 EGO56803.1 - 1.5e-19 69.3 1.5 3.2e-19 68.2 1.5 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Imm52 PF15579.6 EGO56803.1 - 0.18 11.6 0.6 0.82 9.6 0.1 2.2 2 0 0 2 2 2 0 Immunity protein 52 BSD PF03909.17 EGO56805.1 - 2.3e-27 94.8 8.8 9.8e-15 54.3 0.3 3.2 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 EGO56805.1 - 5.5e-23 81.1 0.0 1.2e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Clathrin_lg_ch PF01086.17 EGO56805.1 - 0.015 15.4 1.3 0.015 15.4 1.3 1.8 2 0 0 2 2 2 0 Clathrin light chain DUF3683 PF12447.8 EGO56805.1 - 0.19 11.9 0.7 0.58 10.3 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) Snurportin1 PF11538.8 EGO56805.1 - 2.3 8.5 4.8 24 5.2 3.4 2.4 2 0 0 2 2 2 0 Snurportin1 Clathrin PF00637.20 EGO56806.1 - 1.6e-25 89.6 1.9 6.6e-24 84.4 0.2 3.1 2 1 1 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.8 EGO56806.1 - 7.9e-20 70.8 0.3 7.9e-20 70.8 0.3 2.1 2 0 0 2 2 1 1 Vacuolar protein sorting protein 11 C terminal TPR_11 PF13414.6 EGO56806.1 - 0.00016 21.3 0.3 0.00059 19.5 0.3 2.0 1 0 0 1 1 1 1 TPR repeat zf-C3H2C3 PF17122.5 EGO56806.1 - 0.00043 20.2 0.6 0.00043 20.2 0.6 2.1 2 0 0 2 2 2 1 Zinc-finger TPR_14 PF13428.6 EGO56806.1 - 0.0018 18.9 0.0 0.83 10.6 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO56806.1 - 0.0021 18.3 1.5 0.008 16.5 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-RING_2 PF13639.6 EGO56806.1 - 0.0042 17.4 0.5 0.017 15.4 0.5 2.1 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGO56806.1 - 0.0049 16.8 0.1 0.01 15.8 0.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGO56806.1 - 0.026 14.4 2.4 0.074 12.9 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 EGO56806.1 - 0.032 14.3 1.3 0.074 13.2 0.1 2.4 2 0 0 2 2 1 0 Tetratricopeptide repeat Spc7 PF08317.11 EGO56806.1 - 0.067 12.1 0.5 0.19 10.5 0.5 1.8 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_10 PF13374.6 EGO56806.1 - 0.068 13.1 0.5 0.33 10.9 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGO56806.1 - 0.081 12.1 1.2 3.2 6.9 1.2 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat zf-RING_11 PF17123.5 EGO56806.1 - 0.13 12.0 1.5 0.43 10.4 1.5 1.9 1 0 0 1 1 1 0 RING-like zinc finger ANAPC3 PF12895.7 EGO56806.1 - 0.15 12.3 4.1 11 6.3 0.3 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EGO56806.1 - 0.18 12.1 1.5 0.63 10.4 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGO56806.1 - 0.43 10.5 1.5 1.3 9.0 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TMF_DNA_bd PF12329.8 EGO56806.1 - 4.4 7.4 8.8 14 5.7 3.0 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding BPL_LplA_LipB PF03099.19 EGO56807.1 - 0.00018 21.4 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.21 EGO56808.1 - 6.1e-137 455.7 0.0 7.2e-137 455.5 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase HMGL-like PF00682.19 EGO56809.1 - 1.7e-42 145.8 0.0 1.1e-41 143.2 0.0 2.0 1 1 0 1 1 1 1 HMGL-like DS PF01916.17 EGO56810.1 - 6.3e-131 435.9 0.0 7.2e-131 435.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Myb_DNA-binding PF00249.31 EGO56812.1 - 3.6e-15 55.9 0.0 7.5e-07 29.2 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGO56812.1 - 0.00062 19.6 0.2 0.00062 19.6 0.2 2.9 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EGO56812.1 - 0.0019 18.4 5.9 0.75 10.1 0.5 3.5 3 1 1 4 4 4 2 Myb-like DNA-binding domain EphA2_TM PF14575.6 EGO56813.1 - 0.013 16.4 2.7 0.18 12.7 0.0 2.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 EGO56813.1 - 0.18 11.8 0.1 0.18 11.8 0.1 1.8 2 0 0 2 2 2 0 Syndecan domain Spt20 PF12090.8 EGO56813.1 - 0.22 11.1 13.5 0.037 13.6 9.6 1.8 2 0 0 2 2 2 0 Spt20 family DUF4834 PF16118.5 EGO56813.1 - 0.43 11.6 0.1 0.43 11.6 0.1 4.8 4 1 0 4 4 4 0 Domain of unknown function (DUF4834) DUF1980 PF09323.10 EGO56813.1 - 3.2 7.6 6.6 31 4.4 2.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) PAP2 PF01569.21 EGO56814.1 - 0.022 14.5 4.5 0.49 10.2 0.2 2.1 2 0 0 2 2 2 0 PAP2 superfamily Fungal_trans_2 PF11951.8 EGO56815.1 - 2.9e-56 190.9 0.0 3.9e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 EGO56816.1 - 6.2e-25 87.7 0.0 6.2e-25 87.7 0.0 2.6 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO56816.1 - 4e-09 36.4 9.8 6.8e-09 35.7 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PI3K_1B_p101 PF10486.9 EGO56816.1 - 0.19 9.5 0.3 0.33 8.7 0.3 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Aminotran_3 PF00202.21 EGO56817.1 - 2.8e-104 349.0 0.0 3.8e-104 348.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF257 PF03192.13 EGO56818.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 LPMO_10 PF03067.15 EGO56821.1 - 0.057 14.1 0.1 0.057 14.1 0.1 2.3 3 1 0 3 3 3 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Serglycin PF04360.12 EGO56821.1 - 10 6.1 13.3 1.9 8.4 0.6 2.3 2 0 0 2 2 2 0 Serglycin LsmAD PF06741.13 EGO56823.1 - 1.7e-28 98.9 2.3 1.7e-28 98.9 2.3 2.6 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 EGO56823.1 - 0.0012 18.9 0.0 0.0033 17.5 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain MFS_1 PF07690.16 EGO56826.1 - 1.7e-37 129.2 70.9 5.1e-29 101.3 38.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3511 PF12023.8 EGO56826.1 - 0.12 12.2 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) F-box-like PF12937.7 EGO56827.1 - 0.0033 17.3 0.2 0.0075 16.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO56827.1 - 0.02 14.7 0.2 0.053 13.4 0.2 1.7 1 0 0 1 1 1 0 F-box domain Cupin_8 PF13621.6 EGO56829.1 - 6.6e-36 124.3 0.0 1.2e-35 123.5 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 EGO56829.1 - 5e-16 59.2 0.1 1.5e-15 57.6 0.1 1.7 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase MFS_1 PF07690.16 EGO56829.1 - 9.3e-14 51.1 2.8 9.3e-14 51.1 2.8 2.3 1 1 0 2 2 2 1 Major Facilitator Superfamily Cupin_4 PF08007.12 EGO56829.1 - 2.4e-05 24.0 0.0 2.4e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Cupin superfamily protein Kelch_4 PF13418.6 EGO56829.1 - 0.00029 20.8 3.2 0.0066 16.4 0.0 4.1 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.15 EGO56829.1 - 0.00076 19.4 0.1 0.0042 17.0 0.0 2.4 2 0 0 2 2 2 1 Kelch motif Nodulin-like PF06813.13 EGO56829.1 - 0.83 9.1 9.8 0.75 9.2 5.7 2.5 2 1 0 2 2 2 0 Nodulin-like Mito_carr PF00153.27 EGO56830.1 - 0.076 12.9 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial carrier protein Mito_carr PF00153.27 EGO56831.1 - 1.7e-45 152.9 8.3 1.3e-16 60.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C48 PF02902.19 EGO56832.1 - 3.5e-18 66.2 0.0 8.7e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Phlebovirus_NSM PF07246.11 EGO56832.1 - 1.8 7.9 6.5 3.9 6.8 6.5 1.5 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4449 PF14613.6 EGO56832.1 - 8.8 6.4 9.7 8.7 6.4 2.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) CN_hydrolase PF00795.22 EGO56833.1 - 4.3e-35 121.3 0.1 1.2e-27 96.9 0.1 2.7 2 1 0 2 2 2 2 Carbon-nitrogen hydrolase TipE PF16972.5 EGO56834.1 - 0.73 9.0 6.4 1.3 8.1 6.4 1.4 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE HATPase_c_3 PF13589.6 EGO56835.1 - 1.3e-14 54.2 0.0 2.4e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 EGO56835.1 - 5e-09 36.1 0.0 1.2e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 EGO56835.1 - 0.0033 17.9 0.0 0.01 16.4 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2236 PF09995.9 EGO56836.1 - 1.4e-06 28.7 0.2 2.2e-06 28.1 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Fungal_trans PF04082.18 EGO56837.1 - 1.6e-38 132.2 0.0 3.4e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO56837.1 - 3.3e-09 36.7 28.3 3.5e-08 33.4 9.0 2.8 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Ndc1_Nup PF09531.10 EGO56837.1 - 8.3 5.0 10.3 14 4.2 10.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-C2H2_4 PF13894.6 EGO56840.1 - 0.6 11.1 0.1 0.6 11.1 0.1 3.5 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EGO56840.1 - 1.2 9.6 4.3 8.9 6.7 4.3 2.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) CcmD PF04995.14 EGO56841.1 - 0.12 12.5 0.3 0.23 11.5 0.3 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) p450 PF00067.22 EGO56842.1 - 3.9e-38 131.4 0.0 4.6e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2985 PF11204.8 EGO56843.1 - 4.1e-21 74.9 3.9 6.8e-21 74.2 3.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Plasmodium_Vir PF05795.11 EGO56843.1 - 7.2 5.9 6.1 2.6 7.4 3.0 1.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Ge1_WD40 PF16529.5 EGO56845.1 - 0.0018 17.3 0.1 0.016 14.2 0.0 2.4 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF445 PF04286.12 EGO56845.1 - 0.049 13.4 25.8 0.011 15.6 5.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF445) HEAT_2 PF13646.6 EGO56845.1 - 1.2 9.6 6.4 3.6 8.1 4.2 3.0 1 1 1 2 2 2 0 HEAT repeats AI-2E_transport PF01594.16 EGO56845.1 - 5.6 6.0 4.7 18 4.4 0.1 2.6 3 0 0 3 3 3 0 AI-2E family transporter GlutR_dimer PF00745.20 EGO56845.1 - 7.2 7.1 12.5 37 4.8 5.6 3.9 2 2 1 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain BC10 PF06726.12 EGO56847.1 - 8.2e-18 64.4 10.9 1.5e-17 63.6 10.9 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Y_phosphatase PF00102.27 EGO56852.1 - 4.4e-55 186.8 0.0 5.5e-32 111.2 0.0 3.3 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.20 EGO56852.1 - 3.5e-12 46.8 0.0 1.4e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 EGO56852.1 - 0.13 12.2 0.2 0.24 11.3 0.2 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family AAA PF00004.29 EGO56853.1 - 7.7e-44 149.3 0.0 1.3e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO56853.1 - 2.2e-14 52.9 0.0 4.3e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGO56853.1 - 1.1e-07 31.9 0.0 2.7e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGO56853.1 - 1.4e-07 31.8 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGO56853.1 - 4.3e-06 27.2 0.0 0.00011 22.6 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 EGO56853.1 - 2.4e-05 24.2 3.4 6.4e-05 22.8 3.4 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EGO56853.1 - 2.5e-05 24.6 0.2 0.006 16.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGO56853.1 - 5.7e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGO56853.1 - 0.00058 20.4 0.1 0.019 15.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EGO56853.1 - 0.001 18.4 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EGO56853.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 EGO56853.1 - 0.0026 17.4 0.1 0.0088 15.7 0.1 2.0 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain IstB_IS21 PF01695.17 EGO56853.1 - 0.0028 17.4 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EGO56853.1 - 0.0032 17.3 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EGO56853.1 - 0.008 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EGO56853.1 - 0.0085 15.5 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 KaiC TsaE PF02367.17 EGO56853.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EGO56853.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EGO56853.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EGO56853.1 - 0.023 14.4 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EGO56853.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EGO56853.1 - 0.03 13.8 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 EGO56853.1 - 0.031 14.0 0.0 0.1 12.3 0.0 1.8 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 EGO56853.1 - 0.034 14.2 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGO56853.1 - 0.034 14.5 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase HR1 PF02185.16 EGO56853.1 - 0.052 13.7 0.9 0.13 12.4 0.9 1.6 1 0 0 1 1 1 0 Hr1 repeat AAA_25 PF13481.6 EGO56853.1 - 0.053 13.1 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EGO56853.1 - 0.059 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.9 EGO56853.1 - 0.085 13.1 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Zeta_toxin PF06414.12 EGO56853.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Na_Ca_ex PF01699.24 EGO56855.1 - 8.1e-23 81.0 26.4 4.6e-16 59.1 11.2 3.6 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 EGO56855.1 - 7.2e-17 61.8 10.3 7.2e-17 61.8 10.3 4.4 6 0 0 6 6 6 1 Inner membrane component domain DUF2628 PF10947.8 EGO56855.1 - 5.5 7.4 9.5 5.8 7.3 1.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) DUF1996 PF09362.10 EGO56856.1 - 1.3e-71 241.4 0.8 1.6e-71 241.0 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) EMP70 PF02990.16 EGO56857.1 - 0.005 15.6 0.4 0.0074 15.0 0.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF2207 PF09972.9 EGO56857.1 - 0.024 13.4 0.1 0.034 12.9 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Oxidored_q3 PF00499.20 EGO56857.1 - 0.073 12.8 0.3 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Voltage_CLC PF00654.20 EGO56857.1 - 0.093 12.0 0.6 0.13 11.5 0.6 1.2 1 0 0 1 1 1 0 Voltage gated chloride channel CorA PF01544.18 EGO56857.1 - 0.099 11.9 12.5 0.054 12.8 9.0 2.3 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein UL45 PF05473.12 EGO56857.1 - 0.24 11.0 2.6 0.19 11.3 0.8 1.8 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like Pkinase PF00069.25 EGO56860.1 - 2e-17 63.4 0.0 6.9e-17 61.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO56860.1 - 8.1e-11 41.7 0.1 7.6e-08 32.0 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase DUF4311 PF14188.6 EGO56861.1 - 0.056 13.2 0.0 0.056 13.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) DUF3135 PF11333.8 EGO56861.1 - 0.085 13.1 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) Sugar_tr PF00083.24 EGO56862.1 - 1.1e-55 189.3 8.0 5.3e-34 117.9 0.0 3.0 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 EGO56862.1 - 1.1e-17 64.1 12.7 5.8e-09 35.3 3.0 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily PAP2_3 PF14378.6 EGO56862.1 - 0.0079 15.9 0.5 0.056 13.1 1.0 2.2 2 0 0 2 2 2 1 PAP2 superfamily TRI12 PF06609.13 EGO56862.1 - 0.5 8.7 4.3 0.87 7.9 1.4 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 EGO56862.1 - 0.63 10.6 4.3 0.99 10.0 2.2 2.2 2 0 0 2 2 2 0 Phage holin family 2 Histone PF00125.24 EGO56866.1 - 2.4e-18 66.7 0.0 3.2e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EGO56866.1 - 7.2e-13 48.0 0.1 2e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EGO56866.1 - 3e-05 24.2 0.0 4.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M64 PF09471.10 EGO56866.1 - 0.036 13.6 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 IgA Peptidase M64 HATPase_c_3 PF13589.6 EGO56867.1 - 0.055 13.3 0.2 0.055 13.3 0.2 2.9 3 0 0 3 3 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hydrolase_4 PF12146.8 EGO56868.1 - 3.3e-12 46.2 0.3 5.2e-12 45.5 0.3 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGO56868.1 - 3e-11 44.3 1.3 3.9e-11 44.0 1.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO56868.1 - 2.1e-10 40.7 0.8 1.4e-07 31.5 1.7 2.9 1 1 1 2 2 2 2 alpha/beta hydrolase fold Ndr PF03096.14 EGO56868.1 - 0.016 13.9 0.0 0.072 11.8 0.0 1.8 2 0 0 2 2 2 0 Ndr family SR1P PF13790.6 EGO56869.1 - 0.0066 16.5 3.3 0.026 14.6 2.8 1.8 2 0 0 2 2 2 1 SR1 protein R3H PF01424.22 EGO56871.1 - 6.8e-11 42.0 0.0 1.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 EGO56871.1 - 2.5e-07 30.4 0.0 4.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 EGO56871.1 - 0.03 14.5 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Inositol_P PF00459.25 EGO56872.1 - 2.6e-33 115.7 2.3 3.2e-31 108.8 2.3 2.8 1 1 0 1 1 1 1 Inositol monophosphatase family Exo_endo_phos PF03372.23 EGO56874.1 - 3.1e-08 33.4 0.3 5.4e-08 32.6 0.3 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Bac_luciferase PF00296.20 EGO56875.1 - 1.2e-69 235.2 0.4 1.4e-69 234.9 0.4 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Dicer_N PF17895.1 EGO56883.1 - 0.034 14.0 0.0 0.035 14.0 0.0 1.1 1 0 0 1 1 1 0 Giardia Dicer N-terminal domain Herpes_LMP1 PF05297.11 EGO56884.1 - 3.8 6.6 8.5 4 6.5 8.5 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Glyco_hydro_61 PF03443.14 EGO56889.1 - 3.4e-59 200.2 0.8 4.1e-59 200.0 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3632 PF12311.8 EGO56890.1 - 3e-31 109.2 1.6 4.7e-31 108.5 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) RabGAP-TBC PF00566.18 EGO56891.1 - 4.5e-49 167.0 0.0 7.8e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain adh_short_C2 PF13561.6 EGO56894.1 - 5e-57 193.1 1.9 6.3e-57 192.8 1.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO56894.1 - 1.1e-49 168.6 0.8 1.4e-49 168.3 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO56894.1 - 7.1e-11 42.3 0.8 1.9e-10 41.0 0.8 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO56894.1 - 0.00014 21.4 0.1 0.014 14.8 0.1 3.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGO56894.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Y_phosphatase2 PF03162.13 EGO56895.1 - 3e-46 157.0 0.0 4.6e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGO56895.1 - 3.6e-10 40.2 0.0 5e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EGO56895.1 - 0.0062 16.3 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGO56895.1 - 0.0062 16.1 0.0 0.0092 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Aim19 PF10315.9 EGO56896.1 - 0.00062 20.0 2.8 0.0014 18.9 2.8 1.6 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF1977 PF09320.11 EGO56897.1 - 5.3e-30 103.8 0.5 5.3e-30 103.8 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 EGO56897.1 - 7.7e-23 80.4 0.6 1.5e-22 79.5 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain DUF5528 PF17666.1 EGO56897.1 - 0.055 13.4 0.1 0.095 12.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5528) MINDY_DUB PF04424.13 EGO56898.1 - 7.3e-26 90.5 0.0 1.1e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase CARDB PF07705.11 EGO56898.1 - 0.071 13.4 0.2 0.16 12.3 0.2 1.5 1 0 0 1 1 1 0 CARDB Steroid_dh PF02544.16 EGO56899.1 - 2e-21 76.5 2.1 7.4e-20 71.5 2.1 2.4 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DEAD PF00270.29 EGO56899.1 - 1.9e-18 66.8 0.0 3.2e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EGO56899.1 - 1e-09 39.0 1.2 2.5e-09 37.7 1.2 1.7 1 0 0 1 1 1 1 RecQ zinc-binding DUF1295 PF06966.12 EGO56899.1 - 0.0013 18.3 0.2 0.0025 17.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ydc2-catalyt PF09159.10 EGO56900.1 - 4.8e-77 259.5 0.1 2.1e-73 247.5 0.1 3.4 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 EGO56900.1 - 0.017 15.2 0.0 15 5.7 0.0 3.3 3 0 0 3 3 3 0 Poxvirus A22 protein MRP PF09387.10 EGO56900.1 - 0.019 15.0 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 Mitochondrial RNA binding protein MRP SAP PF02037.27 EGO56900.1 - 0.025 14.3 0.3 0.052 13.3 0.3 1.6 1 0 0 1 1 1 0 SAP domain Pyr_redox_2 PF07992.14 EGO56901.1 - 8.1e-60 202.5 2.3 1e-59 202.2 2.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGO56901.1 - 3e-32 111.1 0.2 7.7e-32 109.8 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGO56901.1 - 3.5e-18 65.9 4.7 7.9e-18 64.8 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO56901.1 - 3.7e-17 62.5 0.5 4.9e-17 62.2 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO56901.1 - 1.1e-05 24.8 0.1 0.00064 19.0 0.0 2.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 EGO56901.1 - 0.00067 19.1 0.3 0.0011 18.5 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 EGO56901.1 - 0.0061 16.2 0.6 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGO56901.1 - 0.0085 14.8 6.3 0.48 9.1 0.1 3.0 2 1 1 3 3 3 2 HI0933-like protein Thi4 PF01946.17 EGO56901.1 - 0.012 14.8 0.2 0.023 13.9 0.2 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EGO56901.1 - 0.12 11.4 6.0 3.1 6.8 2.6 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 EGO56901.1 - 0.17 11.1 5.8 1.3 8.2 0.9 2.7 2 1 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 EGO56901.1 - 0.26 11.5 3.9 0.15 12.3 1.2 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGO56901.1 - 1.5 7.8 6.3 2 7.4 4.3 2.2 2 1 0 2 2 2 0 Glucose inhibited division protein A COX7C PF02935.16 EGO56902.1 - 2.3e-20 72.6 2.9 2.8e-20 72.3 2.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Sec6 PF06046.13 EGO56904.1 - 7.7e-166 552.8 12.7 4.1e-164 547.1 12.7 2.3 1 1 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 EGO56904.1 - 0.00096 18.2 3.3 0.00096 18.2 3.3 2.3 3 0 0 3 3 3 1 Vps53-like, N-terminal NPV_P10 PF05531.12 EGO56904.1 - 0.052 14.0 2.0 7.3 7.1 0.5 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 EGO56904.1 - 0.083 11.5 3.7 0.19 10.3 3.6 1.6 1 1 0 1 1 1 0 AAA domain Vps54_N PF10475.9 EGO56904.1 - 0.13 11.6 6.5 0.19 11.0 2.1 2.3 1 1 1 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex OmdA PF13376.6 EGO56904.1 - 0.32 11.1 1.9 1.3 9.1 0.0 2.9 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated PPR_2 PF13041.6 EGO56905.1 - 4.9e-12 45.8 0.1 0.0032 17.6 0.0 4.8 4 1 1 5 5 5 4 PPR repeat family PPR PF01535.20 EGO56905.1 - 7.2e-10 38.4 2.8 0.00032 20.8 0.0 5.5 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.6 EGO56905.1 - 5.3e-05 23.2 0.0 1.3 9.2 0.0 4.1 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGO56905.1 - 0.00036 20.2 1.9 4.1 7.2 0.0 4.3 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 EGO56905.1 - 0.009 15.4 0.4 0.27 10.6 0.0 2.5 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP GAPT PF11770.8 EGO56905.1 - 0.23 11.3 0.4 0.42 10.4 0.4 1.3 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) MRP-S25 PF13741.6 EGO56906.1 - 1.5e-64 217.7 7.6 9.2e-61 205.3 2.4 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EGO56906.1 - 0.00074 19.8 1.5 0.0028 17.9 1.5 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 Alg14 PF08660.11 EGO56907.1 - 2.4e-53 180.7 0.0 3.2e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF4191 PF13829.6 EGO56907.1 - 0.21 10.9 0.5 0.44 9.9 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Ima1_N PF09779.9 EGO56908.1 - 5.2e-32 111.5 5.4 1.1e-31 110.4 5.4 1.6 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.7 EGO56908.1 - 0.06 13.4 5.4 3.7 7.6 0.6 2.5 2 0 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 EGO56908.1 - 1.5 8.8 7.2 0.068 13.1 0.7 2.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DUF2407 PF10302.9 EGO56910.1 - 7.1e-33 113.3 0.0 1.1e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.6 EGO56910.1 - 1e-20 74.3 0.0 1.9e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain Rad60-SLD_2 PF13881.6 EGO56910.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ras PF00071.22 EGO56911.1 - 1.1e-12 47.8 0.0 1.8e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO56911.1 - 0.034 14.4 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PRCC PF10253.9 EGO56911.1 - 6.5 7.5 7.5 0.51 11.1 1.0 2.0 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Aminotran_1_2 PF00155.21 EGO56912.1 - 2.7e-68 230.8 0.0 3.2e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGO56912.1 - 0.0013 18.1 0.0 0.0027 17.1 0.0 1.3 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EGO56912.1 - 0.0022 16.6 0.0 0.0048 15.5 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EGO56912.1 - 0.0045 16.3 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EGO56912.1 - 0.011 14.7 0.0 0.021 13.8 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class-V Aldedh PF00171.22 EGO56913.1 - 5.3e-27 94.5 0.6 5.8e-27 94.3 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGO56913.1 - 0.0081 15.6 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) LuxC PF05893.14 EGO56913.1 - 0.038 13.0 0.0 0.039 13.0 0.0 1.0 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Ald_Xan_dh_C2 PF02738.18 EGO56914.1 - 7e-210 698.1 1.1 9.6e-210 697.7 1.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EGO56914.1 - 9.1e-47 159.0 0.0 1.9e-46 157.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EGO56914.1 - 5.6e-33 113.2 0.2 2.8e-32 110.9 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 EGO56914.1 - 3.4e-31 107.9 0.1 8.6e-31 106.6 0.1 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 EGO56914.1 - 7.8e-30 102.7 0.0 1.7e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain DUF218 PF02698.17 EGO56914.1 - 0.0068 16.4 0.3 0.063 13.3 0.0 2.5 3 0 0 3 3 3 1 DUF218 domain Fer2 PF00111.27 EGO56914.1 - 0.014 15.3 0.7 0.014 15.3 0.7 3.0 2 2 1 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain SPO22 PF08631.10 EGO56915.1 - 1.1e-74 251.5 9.5 7.3e-74 248.7 2.2 4.2 4 0 0 4 4 4 1 Meiosis protein SPO22/ZIP4 like ADP_PFK_GK PF04587.15 EGO56915.1 - 0.012 14.2 1.0 0.054 12.1 1.0 1.9 1 1 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region TPR_12 PF13424.6 EGO56915.1 - 0.033 14.5 4.6 0.45 10.8 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGO56915.1 - 0.038 14.1 2.6 0.13 12.5 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGO56915.1 - 0.078 12.8 0.3 0.74 9.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_22 PF13401.6 EGO56915.1 - 0.078 13.2 0.7 0.73 10.1 0.0 3.0 4 0 0 4 4 4 0 AAA domain PAS PF00989.25 EGO56916.1 - 0.0046 17.0 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 1 PAS fold HET PF06985.11 EGO56918.1 - 4.8e-26 91.9 7.4 1.4e-25 90.4 7.4 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_C2 PF00648.21 EGO56919.1 - 2.4e-62 210.7 3.0 2.8e-61 207.1 3.0 2.2 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EGO56919.1 - 0.74 10.1 0.0 0.74 10.1 0.0 2.6 2 0 0 2 2 2 0 Calpain large subunit, domain III zf-TRAF PF02176.18 EGO56920.1 - 9.5e-10 39.0 36.8 1.8e-05 25.3 15.0 4.1 1 1 4 5 5 5 4 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 EGO56920.1 - 2.6e-09 36.8 9.7 2.6e-09 36.8 9.7 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO56920.1 - 4.1e-07 29.9 10.0 4.1e-07 29.9 10.0 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGO56920.1 - 1.3e-06 28.2 6.3 1.3e-06 28.2 6.3 3.7 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGO56920.1 - 1.6e-06 28.4 7.2 1.6e-06 28.4 7.2 3.8 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGO56920.1 - 4.9e-06 26.3 8.3 4.9e-06 26.3 8.3 3.2 3 2 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO56920.1 - 1.5e-05 24.7 3.4 1.5e-05 24.7 3.4 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGO56920.1 - 0.00023 21.3 7.0 0.00023 21.3 7.0 2.7 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EGO56920.1 - 0.00038 20.7 4.4 0.00038 20.7 4.4 3.3 3 1 0 3 3 1 1 RING-H2 zinc finger domain zf-Di19 PF05605.12 EGO56920.1 - 0.0057 16.9 8.9 0.0057 16.9 8.9 4.3 3 2 1 4 4 3 2 Drought induced 19 protein (Di19), zinc-binding zf-Nse PF11789.8 EGO56920.1 - 0.013 15.3 10.1 0.013 15.3 10.1 2.9 2 1 1 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-RAG1 PF10426.9 EGO56920.1 - 0.94 9.7 9.0 3.1 8.0 1.8 2.8 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain zf-ACC PF17848.1 EGO56920.1 - 9.5 6.4 12.8 7.7 6.7 0.0 5.0 5 0 0 5 5 5 0 Acetyl-coA carboxylase zinc finger domain Ufd2P_core PF10408.9 EGO56921.1 - 7.4e-210 698.7 7.7 7.4e-210 698.7 7.7 1.3 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.15 EGO56921.1 - 6.8e-26 90.3 1.7 1.9e-25 88.8 1.7 1.8 1 0 0 1 1 1 1 U-box domain Epimerase PF01370.21 EGO56922.1 - 6.8e-18 65.0 0.0 9.5e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO56922.1 - 1.1e-16 60.7 0.0 1.6e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGO56922.1 - 1.5e-11 44.0 0.0 6e-11 42.0 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EGO56922.1 - 3e-10 40.0 0.0 6.8e-10 38.9 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGO56922.1 - 5.9e-08 32.8 0.0 1.1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGO56922.1 - 4.5e-07 29.3 0.0 8.1e-07 28.5 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EGO56922.1 - 0.00017 21.6 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EGO56922.1 - 0.0002 21.9 0.0 0.00054 20.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 EGO56922.1 - 0.00033 20.2 0.0 0.00079 18.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EGO56922.1 - 0.0022 17.1 0.0 0.005 16.0 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 EGO56922.1 - 0.0029 17.2 0.0 0.1 12.1 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family ORC6 PF05460.13 EGO56923.1 - 9.4e-65 219.2 0.5 1.7e-63 215.1 0.0 2.3 2 1 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) Peptidase_M41 PF01434.18 EGO56924.1 - 2.2e-58 197.3 1.9 3.2e-58 196.7 1.2 1.7 2 0 0 2 2 1 1 Peptidase family M41 AAA PF00004.29 EGO56924.1 - 5.7e-30 104.4 0.0 1.1e-26 93.8 0.0 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO56924.1 - 3e-12 46.2 0.1 6e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 EGO56924.1 - 5.2e-05 22.6 0.0 9.9e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EGO56924.1 - 0.00011 22.6 0.4 0.00053 20.4 0.4 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EGO56924.1 - 0.00067 19.7 0.4 0.0033 17.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGO56924.1 - 0.0014 18.4 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 EGO56924.1 - 0.003 18.0 0.0 0.0063 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO56924.1 - 0.0067 16.6 0.1 0.03 14.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGO56924.1 - 0.0094 15.7 1.6 0.037 13.7 0.1 2.6 3 0 0 3 3 3 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGO56924.1 - 0.017 14.5 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EGO56924.1 - 0.017 15.4 0.0 0.053 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGO56924.1 - 0.039 13.5 0.2 0.11 12.1 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGO56924.1 - 0.071 13.3 0.4 0.15 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 EGO56924.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGO56924.1 - 0.12 11.6 1.0 0.64 9.3 0.4 2.3 1 1 1 2 2 2 0 Zeta toxin TsaE PF02367.17 EGO56924.1 - 0.16 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SOG2 PF10428.9 EGO56925.1 - 3.3e-69 234.4 7.9 1.1e-47 163.5 0.0 3.8 3 1 0 4 4 4 2 RAM signalling pathway protein LRR_8 PF13855.6 EGO56925.1 - 1e-17 63.6 0.2 5.5e-08 32.4 0.1 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EGO56925.1 - 5.5e-12 45.7 1.3 0.00085 19.7 0.2 3.8 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGO56925.1 - 0.0023 18.3 2.7 21 6.2 0.1 5.0 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 EGO56925.1 - 0.18 11.9 1.4 2.4 8.4 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat GCN5L1 PF06320.13 EGO56926.1 - 5.6e-15 55.5 0.6 8.8e-15 54.9 0.6 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) CREPT PF16566.5 EGO56926.1 - 0.15 12.2 0.5 0.27 11.4 0.5 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour SOG2 PF10428.9 EGO56926.1 - 4.9 6.2 22.7 6.6 5.8 22.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Steroid_dh PF02544.16 EGO56927.1 - 1.7e-19 70.3 0.3 4.1e-19 69.0 0.0 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EGO56927.1 - 0.00096 18.7 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EGO56927.1 - 0.0042 17.5 0.1 0.016 15.6 0.0 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase rRNA_proc-arch PF13234.6 EGO56928.1 - 1.1e-85 287.8 0.1 4.9e-85 285.7 0.0 2.1 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 EGO56928.1 - 2.4e-50 170.4 3.0 6.3e-50 169.0 2.2 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 EGO56928.1 - 3.7e-18 65.9 0.0 1.4e-17 64.0 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO56928.1 - 1.1e-07 32.1 0.1 1.3e-06 28.8 0.1 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO56928.1 - 5.2e-06 26.6 0.0 5e-05 23.4 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EGO56928.1 - 0.0084 15.2 0.0 0.065 12.3 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein ATPase_2 PF01637.18 EGO56928.1 - 0.035 14.0 1.3 0.093 12.6 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DENN PF02141.21 EGO56929.1 - 1.4e-40 139.2 0.0 2.7e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EGO56929.1 - 1.2e-06 29.2 0.0 3.7e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.11 EGO56929.1 - 0.86 10.2 13.7 0.02 15.4 6.2 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A TMF_TATA_bd PF12325.8 EGO56929.1 - 3.9 7.7 20.9 2.8 8.2 5.4 3.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 EGO56929.1 - 4.9 6.5 22.5 0.64 9.3 10.3 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 EGO56929.1 - 5.5 7.0 19.8 0.43 10.6 8.0 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-HIT PF04438.16 EGO56930.1 - 2.5e-10 40.0 8.4 3.7e-10 39.5 8.4 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 EGO56930.1 - 2 8.6 7.8 5.4 7.2 7.8 1.7 1 0 0 1 1 1 0 MYND finger FDF PF09532.10 EGO56931.1 - 5.3e-27 94.7 2.3 1.4e-26 93.4 2.3 1.8 1 0 0 1 1 1 1 FDF domain LSM14 PF12701.7 EGO56931.1 - 1.8e-24 85.6 0.0 3.3e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 EGO56931.1 - 0.00095 19.3 0.1 0.0028 17.8 0.0 1.8 2 0 0 2 2 2 1 Ataxin 2 SM domain DUF1845 PF08900.11 EGO56931.1 - 0.034 13.9 0.2 0.051 13.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) Tcf25 PF04910.14 EGO56932.1 - 6.5e-58 196.5 0.0 1e-57 195.8 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 PDE4_UCR PF18100.1 EGO56932.1 - 0.043 14.5 0.7 1.4 9.6 0.8 2.7 2 1 1 3 3 3 0 Phosphodiesterase 4 upstream conserved regions (UCR) DUF3246 PF11596.8 EGO56932.1 - 0.27 10.7 4.7 0.5 9.8 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Herpes_DNAp_acc PF04929.12 EGO56932.1 - 1.1 8.2 8.1 2 7.3 8.1 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RRN3 PF05327.11 EGO56932.1 - 3.2 6.2 8.4 6.3 5.2 8.4 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EGO56932.1 - 4.2 5.6 12.5 9.4 4.4 12.5 1.6 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 EGO56932.1 - 5.4 7.1 17.2 12 6.0 17.2 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 HMA PF00403.26 EGO56933.1 - 8.1e-16 58.2 0.4 1.3e-15 57.6 0.4 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Ras_bdg_2 PF14847.6 EGO56933.1 - 0.048 14.0 0.1 0.062 13.6 0.1 1.3 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Pirin PF02678.16 EGO56934.1 - 6e-30 103.4 0.0 1.2e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EGO56934.1 - 4.1e-27 94.6 0.1 1.2e-25 89.9 0.1 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EGO56934.1 - 1e-09 37.9 4.0 2.5e-05 23.9 0.4 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EGO56934.1 - 0.022 14.5 3.3 0.38 10.5 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF861) Perilipin PF03036.16 EGO56935.1 - 1.3e-05 24.4 0.0 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Perilipin family PLD_C PF12357.8 EGO56935.1 - 0.12 12.3 0.0 21 5.1 0.0 2.3 2 0 0 2 2 2 0 Phospholipase D C terminal Thiolase_N PF00108.23 EGO56937.1 - 1.7e-17 63.6 0.1 8e-17 61.5 0.0 2.1 3 0 0 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGO56937.1 - 9.9e-11 41.4 1.2 3.4e-10 39.6 0.2 2.5 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EGO56937.1 - 6.6e-07 29.1 0.2 4.8e-05 23.1 0.1 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EGO56937.1 - 0.0027 17.3 0.1 0.0071 16.0 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 EGO56937.1 - 0.0058 15.4 0.5 0.086 11.5 0.1 2.3 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) DUF4716 PF15837.5 EGO56938.1 - 0.00074 19.5 10.7 0.78 9.8 0.6 3.5 1 1 2 3 3 3 3 Domain of unknown function (DUF4716) PelD_GGDEF PF16963.5 EGO56938.1 - 1.4 8.7 9.8 16 5.3 0.6 3.2 1 1 3 4 4 4 0 PelD GGDEF domain HERV-K_REC PF15695.5 EGO56938.1 - 2.2 8.4 4.6 42 4.3 0.1 3.3 1 1 2 3 3 3 0 Rec (regulator of expression encoded by corf) of HERV-K-113 YqcI_YcgG PF08892.11 EGO56938.1 - 8.5 6.1 13.7 11 5.8 1.1 2.6 1 1 2 3 3 3 0 YqcI/YcgG family DUF3328 PF11807.8 EGO56939.1 - 1.8e-51 175.0 0.4 3e-51 174.3 0.2 1.4 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) SPARC_Ca_bdg PF10591.9 EGO56939.1 - 0.012 15.9 0.1 0.023 15.0 0.1 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Epimerase PF01370.21 EGO56941.1 - 0.031 13.7 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGO56941.1 - 0.079 12.0 0.0 0.19 10.7 0.0 1.6 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HET PF06985.11 EGO56942.1 - 1e-23 84.3 0.0 2.1e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RasGEF PF00617.19 EGO56943.1 - 6.9e-48 163.2 0.3 1.2e-47 162.4 0.3 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGO56943.1 - 1.3e-13 51.1 0.2 3.1e-13 49.9 0.2 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif DEAD PF00270.29 EGO56945.1 - 4.4e-37 127.5 0.0 1.9e-36 125.4 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO56945.1 - 4.3e-23 81.8 0.0 1e-22 80.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGO56945.1 - 1.4e-17 63.6 0.1 2.5e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGO56945.1 - 1.2e-05 25.4 0.9 0.00014 21.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGO56945.1 - 0.1 12.9 1.4 0.33 11.2 0.1 2.4 2 1 0 2 2 2 0 AAA domain Transformer PF06495.11 EGO56945.1 - 1.8 8.6 7.5 3.4 7.7 7.5 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein PPL5 PF18168.1 EGO56945.1 - 3.2 7.0 7.3 4.6 6.4 7.3 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DUF2244 PF10003.9 EGO56946.1 - 0.072 12.8 1.7 0.17 11.6 1.5 1.8 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) KxDL PF10241.9 EGO56948.1 - 1.3e-28 99.1 0.2 1.8e-28 98.6 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein XylR_N PF06505.11 EGO56948.1 - 0.058 13.2 0.2 0.088 12.6 0.2 1.3 1 0 0 1 1 1 0 Activator of aromatic catabolism MPLKIP PF15502.6 EGO56949.1 - 0.31 11.3 3.6 1.9 8.8 3.2 2.5 1 1 0 1 1 1 0 M-phase-specific PLK1-interacting protein GRP PF07172.11 EGO56949.1 - 6.5 7.5 49.2 0.059 14.1 20.2 2.5 3 0 0 3 3 3 0 Glycine rich protein family Cir_N PF10197.9 EGO56950.1 - 1.3e-07 31.7 3.9 1.3e-07 31.7 3.9 2.5 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR AAA PF00004.29 EGO56951.1 - 1.1e-50 171.4 0.0 7.6e-39 133.2 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO56951.1 - 7.4e-10 39.2 0.0 0.0003 21.1 0.0 3.8 2 2 1 3 3 3 2 AAA domain AAA_lid_3 PF17862.1 EGO56951.1 - 7.8e-10 38.4 0.1 2e-09 37.1 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGO56951.1 - 5.7e-09 36.6 0.0 0.0024 18.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 EGO56951.1 - 7.8e-08 31.9 0.1 0.013 14.7 0.0 2.5 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_14 PF13173.6 EGO56951.1 - 2e-07 31.1 0.0 0.003 17.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 EGO56951.1 - 1.1e-06 28.3 0.5 2e-05 24.2 0.1 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 ATPase_2 PF01637.18 EGO56951.1 - 2.1e-06 27.8 0.1 3 7.7 0.0 4.4 3 2 1 5 5 4 1 ATPase domain predominantly from Archaea AAA_2 PF07724.14 EGO56951.1 - 3.8e-06 27.1 0.0 0.00012 22.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 EGO56951.1 - 8.6e-06 25.6 0.0 0.017 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EGO56951.1 - 1e-05 25.5 0.1 0.0022 18.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGO56951.1 - 1.5e-05 25.2 0.0 0.19 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EGO56951.1 - 1.6e-05 24.7 0.0 0.27 11.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 EGO56951.1 - 2.9e-05 23.9 0.2 0.092 12.5 0.1 3.0 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGO56951.1 - 4.8e-05 23.9 0.0 0.099 13.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 EGO56951.1 - 0.00011 21.6 0.7 0.0048 16.3 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EGO56951.1 - 0.00017 21.2 0.4 0.053 13.0 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EGO56951.1 - 0.00025 21.4 0.0 0.087 13.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 EGO56951.1 - 0.00035 20.6 0.0 0.51 10.4 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EGO56951.1 - 0.00044 20.2 1.5 0.8 9.6 0.0 3.4 4 0 0 4 4 3 1 NACHT domain Sigma54_activat PF00158.26 EGO56951.1 - 0.00051 19.8 0.0 1.3 8.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 EGO56951.1 - 0.00051 20.6 0.1 0.098 13.2 0.1 2.4 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 EGO56951.1 - 0.0011 18.2 0.1 1.1 8.4 0.1 2.4 2 0 0 2 2 2 2 NB-ARC domain ATPase PF06745.13 EGO56951.1 - 0.0013 18.1 0.2 0.022 14.1 0.2 2.3 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 EGO56951.1 - 0.0022 17.6 1.7 3.5 7.2 0.0 3.5 4 1 0 4 4 3 2 AAA domain PhoH PF02562.16 EGO56951.1 - 0.0056 16.1 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Parvo_NS1 PF01057.17 EGO56951.1 - 0.0098 15.0 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 TniB PF05621.11 EGO56951.1 - 0.013 15.0 0.2 6.5 6.1 0.1 3.3 3 1 0 3 3 3 0 Bacterial TniB protein AAA_28 PF13521.6 EGO56951.1 - 0.016 15.5 0.0 0.78 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EGO56951.1 - 0.016 15.2 0.0 10 6.0 0.0 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain AAA_19 PF13245.6 EGO56951.1 - 0.023 15.1 0.1 0.39 11.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain CPT PF07931.12 EGO56951.1 - 0.026 14.4 0.0 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 EGO56951.1 - 0.031 14.0 0.4 8.1 6.3 0.0 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 EGO56951.1 - 0.036 13.8 0.0 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase AAA_3 PF07726.11 EGO56951.1 - 0.043 13.7 0.0 0.76 9.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGO56951.1 - 0.055 13.2 0.0 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EGO56951.1 - 0.063 13.2 0.0 9.7 6.1 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_17 PF13207.6 EGO56951.1 - 0.1 13.0 0.0 14 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGO56951.1 - 0.1 12.3 0.0 0.57 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 EGO56951.1 - 0.19 11.7 0.0 0.59 10.2 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Band_7 PF01145.25 EGO56952.1 - 2.6e-27 96.0 5.1 4e-27 95.4 5.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EGO56952.1 - 0.021 14.5 0.4 0.033 13.9 0.4 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Thioredoxin_7 PF13899.6 EGO56954.1 - 1.1 9.4 3.6 21 5.4 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin-like Ribosomal_S2 PF00318.20 EGO56955.1 - 1.6e-24 86.4 0.2 2.1e-13 50.0 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EGO56955.1 - 0.0001 23.6 14.6 0.00019 22.8 14.6 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus vATP-synt_AC39 PF01992.16 EGO56956.1 - 4.1e-110 368.4 0.0 4.6e-110 368.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.18 EGO56957.1 - 4.6e-79 265.1 0.2 4.6e-79 265.1 0.2 2.3 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGO56957.1 - 2.1e-20 72.9 2.1 2.1e-20 72.9 2.1 2.8 2 0 0 2 2 2 1 NOP5NT (NUC127) domain SPT6_acidic PF14632.6 EGO56957.1 - 0.0021 18.6 14.2 0.0021 18.6 14.2 3.2 2 1 0 2 2 2 1 Acidic N-terminal SPT6 ubiquitin PF00240.23 EGO56958.1 - 8.8e-06 25.4 0.0 9.4e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 EGO56958.1 - 0.00073 20.2 0.0 0.0012 19.5 0.0 1.4 1 1 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.6 EGO56958.1 - 0.05 14.1 0.1 0.32 11.5 0.1 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain TGF_beta_GS PF08515.12 EGO56960.1 - 0.1 12.1 0.9 0.12 11.8 0.9 1.2 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif CBFD_NFYB_HMF PF00808.23 EGO56962.1 - 3.1e-05 24.2 0.1 3.8e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 EGO56962.1 - 0.0012 19.1 0.0 0.0012 19.0 0.0 1.1 1 0 0 1 1 1 1 CENP-W protein TAFII28 PF04719.14 EGO56962.1 - 0.091 12.9 0.6 0.13 12.4 0.6 1.4 1 1 0 1 1 1 0 hTAFII28-like protein conserved region Prefoldin_2 PF01920.20 EGO56963.1 - 1.2e-23 83.1 9.1 1.7e-23 82.6 9.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit JIP_LZII PF16471.5 EGO56963.1 - 0.015 15.5 0.2 0.015 15.5 0.2 2.6 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II AAA_23 PF13476.6 EGO56963.1 - 0.041 14.4 12.5 0.051 14.1 12.5 1.1 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.12 EGO56963.1 - 0.44 10.6 2.3 2.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MtrG PF04210.13 EGO56963.1 - 2.7 7.9 5.0 1.8 8.4 0.1 2.3 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4140 PF13600.6 EGO56963.1 - 4.2 7.9 9.4 12 6.4 0.0 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) MFS_1 PF07690.16 EGO56964.1 - 1.1e-37 129.8 35.7 1.1e-37 129.8 35.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO56964.1 - 6e-10 38.6 10.9 6e-10 38.6 10.9 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EGO56964.1 - 8.4e-05 22.0 2.2 8.4e-05 22.0 2.2 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB PTR2 PF00854.21 EGO56964.1 - 0.0021 16.9 0.8 0.0044 15.9 0.8 1.4 1 0 0 1 1 1 1 POT family Phosphoesterase PF04185.14 EGO56966.1 - 9.7e-28 97.4 0.4 1.2e-26 93.8 0.4 2.0 1 1 0 1 1 1 1 Phosphoesterase family DASH_Dad1 PF08649.10 EGO56967.1 - 2.1e-27 95.1 2.4 2.8e-27 94.7 2.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 SUIM_assoc PF16619.5 EGO56967.1 - 0.00041 20.4 4.9 0.00072 19.6 4.9 1.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF5523 PF17661.1 EGO56967.1 - 0.01 15.6 10.7 0.011 15.5 10.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) WVELL PF14043.6 EGO56967.1 - 0.011 15.5 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 0 WVELL protein DASH_Dad4 PF08650.10 EGO56967.1 - 0.016 15.2 0.4 0.025 14.5 0.4 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad4 zf-C2H2_3rep PF18868.1 EGO56967.1 - 0.048 14.3 0.4 0.062 14.0 0.4 1.4 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats V_ATPase_I PF01496.19 EGO56967.1 - 0.061 11.3 6.8 0.066 11.1 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4834 PF16118.5 EGO56967.1 - 0.08 13.9 4.7 0.13 13.2 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 EGO56967.1 - 0.29 10.7 14.1 0.36 10.4 14.1 1.2 1 0 0 1 1 1 0 Spt20 family DUF4746 PF15928.5 EGO56967.1 - 0.31 10.4 7.8 0.3 10.5 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF913 PF06025.12 EGO56967.1 - 0.31 10.0 3.6 0.37 9.7 3.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.17 EGO56967.1 - 0.5 10.5 6.1 0.58 10.3 6.1 1.1 1 0 0 1 1 1 0 DDHD domain ORC_WH_C PF18137.1 EGO56967.1 - 0.94 9.5 7.3 1.6 8.8 7.3 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Presenilin PF01080.17 EGO56967.1 - 1.5 7.5 7.3 1.6 7.4 7.3 1.1 1 0 0 1 1 1 0 Presenilin Skp1_POZ PF03931.15 EGO56969.1 - 5.4e-10 39.3 0.0 8.5e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 EGO56969.1 - 0.0027 17.9 0.0 0.0037 17.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Ras PF00071.22 EGO56970.1 - 3.7e-49 166.4 0.0 4.6e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO56970.1 - 3.1e-20 72.6 0.0 5.7e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO56970.1 - 2.1e-05 24.1 0.0 5.2e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 EGO56970.1 - 0.037 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2470 PF10615.9 EGO56972.1 - 2.8e-24 85.5 0.9 4.1e-24 85.0 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) CARD_2 PF16739.5 EGO56973.1 - 0.046 13.7 0.2 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 Caspase recruitment domain UxaC PF02614.14 EGO56975.1 - 0.013 14.4 0.4 0.055 12.3 0.4 1.7 2 0 0 2 2 2 0 Glucuronate isomerase DUF4972 PF16342.5 EGO56975.1 - 0.036 13.7 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) FAM25 PF15825.5 EGO56975.1 - 0.19 12.1 0.2 0.37 11.2 0.2 1.4 1 0 0 1 1 1 0 FAM25 family EzrA PF06160.12 EGO56976.1 - 0.0028 15.9 1.4 0.0034 15.6 1.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF1539 PF07560.11 EGO56976.1 - 0.0042 17.2 0.7 0.0055 16.8 0.7 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1539) SesA PF17107.5 EGO56976.1 - 0.0071 16.5 1.4 0.0097 16.1 1.1 1.5 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TMCO5 PF14992.6 EGO56976.1 - 0.0084 15.7 3.0 0.011 15.3 3.0 1.2 1 0 0 1 1 1 1 TMCO5 family AvrM-A PF18241.1 EGO56976.1 - 0.016 15.6 2.8 0.028 14.8 2.8 1.4 1 1 0 1 1 1 0 Flax-rust effector AvrM-A YkyA PF10368.9 EGO56976.1 - 0.095 12.4 5.0 0.18 11.4 4.9 1.6 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein FANCI_S2 PF14676.6 EGO56976.1 - 0.097 13.0 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 2 HSCB_C PF07743.13 EGO56976.1 - 0.37 11.3 3.6 2.2 8.8 1.5 2.2 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Aldedh PF00171.22 EGO56977.1 - 3.6e-188 625.8 0.2 4.1e-188 625.6 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family IPI_T4 PF11634.8 EGO56977.1 - 0.16 12.0 0.7 1.9 8.5 0.1 2.5 2 0 0 2 2 2 0 Nuclease inhibitor from bacteriophage T4 TRF PF08558.10 EGO56978.1 - 2.1e-57 194.5 0.5 3e-57 194.0 0.5 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 EGO56978.1 - 0.00018 21.6 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Fungal_trans PF04082.18 EGO56979.1 - 4.3e-12 45.6 0.9 9.5e-12 44.5 0.9 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO56979.1 - 2.5e-07 30.7 7.6 5.1e-07 29.7 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRF PF06875.11 EGO56979.1 - 0.15 11.5 0.0 0.5 9.8 0.0 1.8 2 0 0 2 2 2 0 Plethodontid receptivity factor PRF zf-H2C2_2 PF13465.6 EGO56983.1 - 6.2e-18 64.3 17.7 7.5e-06 26.1 0.9 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 EGO56983.1 - 1.3e-16 60.0 26.7 5.8e-05 23.3 1.8 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO56983.1 - 2.4e-06 27.9 24.5 0.049 14.5 1.2 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGO56983.1 - 0.01 16.1 0.8 29 5.1 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EGO56983.1 - 0.014 16.0 11.8 4 8.1 0.3 4.0 1 1 3 4 4 4 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 EGO56983.1 - 0.48 10.2 5.0 0.7 9.7 0.1 2.7 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 EGO56983.1 - 5 7.2 5.3 8.7 6.5 0.0 3.0 1 1 3 4 4 4 0 Aberrant zinc-finger EF-hand_6 PF13405.6 EGO56985.1 - 1.3e-08 34.1 1.5 0.0015 18.3 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGO56985.1 - 2.7e-06 27.8 0.5 5.8e-06 26.7 0.5 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGO56985.1 - 0.00037 19.8 2.3 0.0017 17.7 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EGO56985.1 - 0.016 14.7 1.4 0.023 14.2 0.1 1.9 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 EGO56985.1 - 0.019 14.8 0.5 0.062 13.2 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain pair Met_10 PF02475.16 EGO56986.1 - 9.3e-07 28.8 0.0 2.5e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Met-10+ like-protein Thr_synth_N PF14821.6 EGO56989.1 - 3.6e-28 97.6 0.0 7.2e-28 96.6 0.0 1.5 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 EGO56989.1 - 1.1e-20 74.3 0.0 4.7e-20 72.2 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DSPc PF00782.20 EGO56991.1 - 2.4e-25 88.9 0.0 2.8e-19 69.3 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGO56991.1 - 0.0029 17.2 0.1 0.029 13.9 0.2 2.2 2 1 0 2 2 2 1 Protein-tyrosine phosphatase PhnG PF06754.12 EGO56992.1 - 0.12 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG CVNH PF08881.10 EGO56993.1 - 4.4e-37 126.8 1.2 3.5e-23 82.2 0.3 2.4 2 0 0 2 2 2 2 CVNH domain CdvA PF18822.1 EGO56994.1 - 0.00048 20.0 18.5 0.0011 18.8 7.8 3.0 1 1 1 2 2 2 1 CdvA-like coiled-coil domain Rootletin PF15035.6 EGO56994.1 - 0.00078 19.5 36.6 0.25 11.3 20.5 2.9 1 1 1 2 2 2 2 Ciliary rootlet component, centrosome cohesion FAM76 PF16046.5 EGO56994.1 - 0.0011 18.4 7.4 0.0011 18.4 7.4 2.3 1 1 2 3 3 3 1 FAM76 protein PRKG1_interact PF15898.5 EGO56994.1 - 0.0018 19.1 26.4 0.2 12.6 14.0 2.5 1 1 1 2 2 2 2 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 EGO56994.1 - 0.0024 18.3 32.5 0.48 10.9 11.2 4.5 1 1 2 3 3 3 2 Cell division protein ZapB KLRAQ PF10205.9 EGO56994.1 - 0.0028 17.8 9.3 0.0028 17.8 9.3 2.5 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein SHE3 PF17078.5 EGO56994.1 - 0.0049 16.6 12.9 0.0049 16.6 12.9 2.4 1 1 1 2 2 2 1 SWI5-dependent HO expression protein 3 DUF4201 PF13870.6 EGO56994.1 - 0.013 15.3 26.9 0.067 12.9 14.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) GAS PF13851.6 EGO56994.1 - 0.05 12.9 28.1 0.024 14.0 6.4 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 EGO56994.1 - 0.071 12.9 31.6 0.05 13.4 2.9 4.3 2 1 2 4 4 4 0 Septum formation initiator FPP PF05911.11 EGO56994.1 - 0.091 10.9 19.1 0.31 9.2 19.1 1.7 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 EGO56994.1 - 0.097 11.5 25.9 0.018 13.9 15.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein kleA_kleC PF17383.2 EGO56994.1 - 0.11 12.8 0.7 0.11 12.8 0.7 3.9 1 1 4 5 5 5 0 Uncharacterized KorC regulated protein A HALZ PF02183.18 EGO56994.1 - 0.18 12.1 28.8 0.7 10.2 3.0 5.3 3 2 1 5 5 5 0 Homeobox associated leucine zipper ATG16 PF08614.11 EGO56994.1 - 0.23 11.7 36.1 0.21 11.8 9.6 3.0 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Jnk-SapK_ap_N PF09744.9 EGO56994.1 - 0.24 11.6 26.0 0.093 13.0 11.3 2.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CENP-F_leu_zip PF10473.9 EGO56994.1 - 0.25 11.3 24.5 0.25 11.4 7.1 2.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 EGO56994.1 - 0.56 10.6 10.2 8.6 6.8 0.2 4.3 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF4047 PF13256.6 EGO56994.1 - 0.57 10.4 5.6 0.57 10.4 2.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4047) Cep57_CLD_2 PF14197.6 EGO56994.1 - 0.94 9.6 35.0 1.2 9.3 5.3 4.4 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 UPF0242 PF06785.11 EGO56994.1 - 1.4 9.0 28.8 0.55 10.3 18.5 2.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus BLOC1_2 PF10046.9 EGO56994.1 - 1.8 8.9 16.3 1 9.7 1.3 3.3 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 EGO56994.1 - 2 8.8 24.4 13 6.2 24.3 2.0 1 1 0 1 1 1 0 Fez1 Scaffolding_pro PF11418.8 EGO56994.1 - 2.5 8.7 10.7 1 10.0 0.5 3.6 1 1 1 3 3 3 0 Phi29 scaffolding protein ADIP PF11559.8 EGO56994.1 - 3 7.9 29.8 3 7.9 15.9 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 EGO56994.1 - 3.2 8.1 23.4 0.63 10.4 10.6 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EGO56994.1 - 3.4 8.3 17.8 0.24 12.1 0.9 3.8 1 1 2 3 3 3 0 SlyX YabA PF06156.13 EGO56994.1 - 3.5 8.3 24.6 2.3 8.9 6.8 3.9 1 1 0 2 2 2 0 Initiation control protein YabA BST2 PF16716.5 EGO56994.1 - 3.6 8.2 19.8 3.8 8.2 2.2 3.7 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 DUF1053 PF06327.14 EGO56994.1 - 5.1 7.7 10.7 0.11 13.0 2.4 2.3 2 1 1 3 3 2 0 Domain of Unknown Function (DUF1053) DUF4407 PF14362.6 EGO56994.1 - 5.5 6.2 20.2 31 3.8 20.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.6 EGO56994.1 - 7.4 6.6 15.3 0.24 11.4 1.5 3.2 1 1 3 4 4 4 0 FlxA-like protein DUF1664 PF07889.12 EGO56994.1 - 8.4 6.5 9.3 4.3 7.4 2.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Acetyltransf_11 PF13720.6 EGO56994.1 - 9.6 6.7 8.8 15 6.1 0.1 2.8 2 1 1 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Lebercilin PF15619.6 EGO56996.1 - 0.00035 20.3 26.2 0.00035 20.3 26.2 1.5 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease ZapB PF06005.12 EGO56996.1 - 0.017 15.6 14.6 0.017 15.6 14.6 3.4 2 1 1 3 3 3 0 Cell division protein ZapB DUF5082 PF16888.5 EGO56996.1 - 0.023 15.0 17.9 0.32 11.3 0.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Shugoshin_N PF07558.11 EGO56996.1 - 0.086 12.7 11.3 0.32 10.9 7.9 2.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region CENP-H PF05837.12 EGO56996.1 - 0.36 11.2 24.4 0.57 10.6 15.8 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TSC22 PF01166.18 EGO56996.1 - 0.43 10.9 15.5 8 6.9 8.9 3.4 1 1 0 2 2 2 0 TSC-22/dip/bun family GAS PF13851.6 EGO56996.1 - 0.47 9.8 29.3 2 7.7 6.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 EGO56996.1 - 0.86 10.0 33.5 6.2 7.2 33.5 2.0 1 1 0 1 1 1 0 Fez1 FapA PF03961.13 EGO56996.1 - 1.2 7.7 11.8 2 6.9 11.8 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMF_DNA_bd PF12329.8 EGO56996.1 - 2.2 8.4 28.1 3.5 7.7 3.2 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.19 EGO56996.1 - 2.3 6.0 14.8 2.9 5.7 14.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 EGO56996.1 - 3.3 8.4 26.7 0.13 12.9 11.6 3.1 2 1 1 3 3 3 0 Initiation control protein YabA DivIC PF04977.15 EGO56996.1 - 5.1 6.9 27.4 5.5 6.8 5.2 3.4 1 1 2 3 3 3 0 Septum formation initiator DASH_Dam1 PF08653.10 EGO56996.1 - 5.9 6.8 6.9 13 5.6 0.4 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 Hid1 PF12722.7 EGO56996.1 - 6.9 4.7 18.9 9.4 4.2 18.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Smg4_UPF3 PF03467.15 EGO56997.1 - 1.4e-37 129.4 0.5 1.4e-37 129.4 0.5 6.0 6 2 0 6 6 6 1 Smg-4/UPF3 family RRM_1 PF00076.22 EGO56997.1 - 3.1e-09 36.5 0.3 1.7e-07 30.9 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 EGO56998.1 - 1.8e-32 113.5 0.0 2.9e-31 109.6 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EGO56998.1 - 0.03 13.9 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Pkinase_fungal PF17667.1 EGO57000.1 - 5.8e-134 446.9 0.0 7.1e-134 446.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGO57000.1 - 0.00017 21.0 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGO57000.1 - 0.0044 17.0 0.0 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family MauJ PF17419.2 EGO57000.1 - 0.06 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Methylamine utilization protein MauJ SDA1 PF05285.12 EGO57001.1 - 7.2e-05 22.4 38.2 8.1e-05 22.2 38.2 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 EGO57001.1 - 0.00031 20.2 34.0 0.00035 20.0 34.0 1.1 1 0 0 1 1 1 1 BUD22 DUF2457 PF10446.9 EGO57001.1 - 0.0063 15.7 43.2 0.0063 15.7 43.2 2.1 1 1 1 2 2 1 1 Protein of unknown function (DUF2457) Nop14 PF04147.12 EGO57001.1 - 0.0091 14.3 48.3 0.012 13.9 48.3 1.1 1 0 0 1 1 1 1 Nop14-like family Presenilin PF01080.17 EGO57001.1 - 0.026 13.3 21.8 0.033 13.0 21.8 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 EGO57001.1 - 0.052 11.7 20.7 0.063 11.4 20.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4045 PF13254.6 EGO57001.1 - 0.099 12.3 13.6 0.11 12.1 13.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Raftlin PF15250.6 EGO57001.1 - 0.15 10.8 15.9 0.18 10.5 15.9 1.1 1 0 0 1 1 1 0 Raftlin LAP1C PF05609.12 EGO57001.1 - 0.18 10.9 19.6 0.23 10.5 19.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SLC12 PF03522.15 EGO57001.1 - 0.42 9.6 18.6 0.48 9.4 18.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CCSAP PF15748.5 EGO57001.1 - 0.46 10.6 21.8 0.7 10.0 21.8 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Lin-8 PF03353.15 EGO57001.1 - 0.48 9.9 24.2 0.55 9.7 24.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Peptidase_S64 PF08192.11 EGO57001.1 - 1.1 7.7 19.5 1.4 7.3 19.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Neur_chan_memb PF02932.16 EGO57001.1 - 1.7 8.7 10.1 2.7 8.0 10.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Merozoite_SPAM PF07133.11 EGO57001.1 - 1.9 8.5 62.7 3.8 7.5 62.7 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop53 PF07767.11 EGO57001.1 - 4 6.7 37.8 6.4 6.1 37.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TFIIF_alpha PF05793.12 EGO57001.1 - 5.7 5.4 54.6 7.9 4.9 54.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SpoVIF PF14069.6 EGO57005.1 - 0.17 11.6 0.0 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Stage VI sporulation protein F P16-Arc PF04699.14 EGO57007.1 - 6.9e-51 172.6 0.0 8.1e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Methyltransf_23 PF13489.6 EGO57008.1 - 5.6e-08 32.8 0.0 9.8e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO57008.1 - 1.2e-07 32.3 0.0 2.9e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO57008.1 - 6e-06 26.9 0.0 2.2e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO57008.1 - 7.5e-06 26.6 0.0 1.5e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO57008.1 - 0.0019 18.0 0.0 0.0094 15.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO57008.1 - 0.058 12.7 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Adaptin_N PF01602.20 EGO57009.1 - 5.9e-124 414.5 11.1 7.3e-124 414.2 11.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EGO57009.1 - 7.1e-48 161.5 0.0 1.9e-47 160.1 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EGO57009.1 - 1.1e-15 57.9 0.0 2.1e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain RasGEF_N_2 PF14663.6 EGO57009.1 - 0.017 15.5 0.3 3.8 7.9 0.1 3.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RTP1_C1 PF10363.9 EGO57009.1 - 0.039 14.1 0.2 0.18 12.0 0.2 2.2 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 ANAPC4_WD40 PF12894.7 EGO57010.1 - 0.00017 21.8 0.0 0.21 11.9 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO57010.1 - 0.0025 18.6 0.8 1.2 10.1 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Hira PF07569.11 EGO57010.1 - 0.053 13.2 0.1 0.52 10.0 0.0 2.3 3 0 0 3 3 3 0 TUP1-like enhancer of split G6PD_bact PF10786.9 EGO57010.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) HET PF06985.11 EGO57012.1 - 7.7e-28 97.7 0.0 1.3e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 2OG-FeII_Oxy_3 PF13640.6 EGO57013.1 - 2.2e-10 41.3 0.0 4.4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4096 PF13340.6 EGO57013.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) Trehalose_recp PF06151.13 EGO57014.1 - 0.0063 15.2 0.0 0.0087 14.7 0.0 1.1 1 0 0 1 1 1 1 Trehalose receptor Ino80_Iec3 PF14612.6 EGO57014.1 - 0.29 11.8 3.1 0.47 11.1 3.1 1.3 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Uds1 PF15456.6 EGO57022.1 - 1.3e-34 119.2 10.9 1.3e-34 119.2 10.9 7.7 4 1 2 7 7 7 3 Up-regulated During Septation DUF349 PF03993.12 EGO57022.1 - 0.069 13.4 0.4 0.069 13.4 0.4 6.9 6 2 1 7 7 7 0 Domain of Unknown Function (DUF349) DUF1751 PF08551.10 EGO57023.1 - 1.7e-06 28.5 0.1 2.9e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EGO57023.1 - 5.6e-06 26.4 4.5 1.7e-05 24.9 4.5 1.7 1 1 0 1 1 1 1 Rhomboid family Gly-zipper_Omp PF13488.6 EGO57023.1 - 0.051 13.6 2.3 0.22 11.5 0.1 2.4 2 0 0 2 2 2 0 Glycine zipper Prenyltransf PF01255.19 EGO57024.1 - 2e-84 282.6 0.1 3.4e-84 281.9 0.1 1.3 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase ING PF12998.7 EGO57025.1 - 2.1e-08 34.7 0.0 0.00013 22.5 0.0 2.6 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EGO57025.1 - 5.5e-07 29.4 6.1 9.5e-07 28.6 6.1 1.4 1 0 0 1 1 1 1 PHD-finger LRR_6 PF13516.6 EGO57026.1 - 0.00014 21.7 0.3 0.69 10.1 0.0 4.7 4 0 0 4 4 4 1 Leucine Rich repeat F-box-like PF12937.7 EGO57026.1 - 0.015 15.2 0.1 0.038 13.9 0.1 1.8 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.7 EGO57026.1 - 0.062 13.8 1.3 4.2 7.9 0.0 4.0 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) V_ATPase_I PF01496.19 EGO57027.1 - 0 1044.0 0.0 0 1043.9 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.21 EGO57027.1 - 0.0043 16.7 3.6 0.23 11.0 0.3 2.2 2 0 0 2 2 2 2 Intermediate filament protein DUF1664 PF07889.12 EGO57027.1 - 0.02 15.0 1.3 2 8.5 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) SesA PF17107.5 EGO57027.1 - 0.03 14.5 1.6 0.68 10.1 0.1 3.0 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Snapin_Pallidin PF14712.6 EGO57027.1 - 0.035 14.5 2.8 1.9 9.0 0.0 3.1 3 0 0 3 3 3 0 Snapin/Pallidin Baculo_PEP_C PF04513.12 EGO57027.1 - 0.045 13.8 1.8 5.2 7.1 0.7 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CheZ PF04344.13 EGO57027.1 - 0.045 13.7 1.1 0.25 11.3 0.1 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF3584 PF12128.8 EGO57027.1 - 0.061 10.8 3.1 0.22 9.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) LXG PF04740.12 EGO57027.1 - 0.065 12.9 3.7 3.7 7.2 0.1 2.3 2 0 0 2 2 2 0 LXG domain of WXG superfamily Lectin_N PF03954.14 EGO57027.1 - 0.13 12.0 2.8 1.8 8.3 0.3 2.7 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain CENP-F_leu_zip PF10473.9 EGO57027.1 - 0.16 12.0 3.9 1.1 9.3 0.2 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5320 PF17253.2 EGO57027.1 - 0.2 12.7 1.1 16 6.7 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF1515 PF07439.11 EGO57027.1 - 0.24 11.4 0.0 0.24 11.4 0.0 2.3 3 0 0 3 3 2 0 Protein of unknown function (DUF1515) COG5 PF10392.9 EGO57027.1 - 0.27 11.4 1.8 6.9 6.9 0.1 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 ZapB PF06005.12 EGO57027.1 - 0.31 11.5 4.8 4.5 7.8 0.2 2.6 2 0 0 2 2 2 0 Cell division protein ZapB DASH_Dam1 PF08653.10 EGO57027.1 - 0.33 10.8 1.8 7.3 6.5 0.1 3.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 Nup54 PF13874.6 EGO57027.1 - 0.34 11.0 3.9 2.9 8.0 0.1 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF4988 PF16378.5 EGO57027.1 - 0.49 10.0 1.5 0.54 9.9 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function UPF0449 PF15136.6 EGO57027.1 - 0.64 10.5 2.2 13 6.3 0.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Rab5-bind PF09311.11 EGO57027.1 - 0.74 9.1 4.4 1.2 8.5 0.3 2.1 2 0 0 2 2 2 0 Rabaptin-like protein FAM184 PF15665.5 EGO57027.1 - 0.85 9.4 4.5 0.59 9.9 0.3 2.1 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B CLZ PF16526.5 EGO57027.1 - 1.1 9.7 5.8 19 5.7 0.1 3.0 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Prefoldin_2 PF01920.20 EGO57027.1 - 1.7 8.7 6.4 3.6 7.6 0.3 2.7 3 0 0 3 3 2 0 Prefoldin subunit Golgin_A5 PF09787.9 EGO57027.1 - 1.7 8.0 6.0 1.5 8.2 1.2 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 RasGAP_C PF03836.15 EGO57027.1 - 1.8 8.7 3.8 3.4 7.8 0.5 2.5 2 0 0 2 2 2 0 RasGAP C-terminus Spc24 PF08286.11 EGO57027.1 - 2.6 8.3 4.9 11 6.4 0.1 2.7 3 0 0 3 3 2 0 Spc24 subunit of Ndc80 DivIC PF04977.15 EGO57027.1 - 8.9 6.2 9.0 6 6.7 0.8 2.9 2 0 0 2 2 2 0 Septum formation initiator Macro PF01661.21 EGO57028.1 - 1.2e-10 41.4 0.0 0.00046 20.2 0.0 2.8 2 0 0 2 2 2 2 Macro domain TFIID-18kDa PF02269.16 EGO57029.1 - 1.7e-19 69.6 0.0 3.3e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.6 EGO57029.1 - 0.00011 22.5 0.0 0.00025 21.4 0.0 1.6 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGO57029.1 - 0.00024 21.2 0.0 0.00046 20.3 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EGO57029.1 - 0.00097 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated DUF4746 PF15928.5 EGO57029.1 - 0.041 13.3 4.6 0.047 13.1 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4175 PF13779.6 EGO57029.1 - 0.11 10.4 7.8 0.13 10.2 7.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Histone PF00125.24 EGO57029.1 - 0.12 12.8 0.0 0.12 12.8 0.0 2.5 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Pes-10 PF07149.11 EGO57029.1 - 2.5 7.1 8.8 0.014 14.5 0.7 1.3 2 0 0 2 2 2 0 Pes-10 DUF4407 PF14362.6 EGO57029.1 - 5.7 6.2 6.7 7.5 5.8 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1242 PF06842.12 EGO57030.1 - 1.3e-17 63.3 1.2 1.8e-17 62.8 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1242) Tcp11 PF05794.13 EGO57032.1 - 6.3e-104 348.5 0.0 1e-103 347.8 0.0 1.3 1 0 0 1 1 1 1 T-complex protein 11 DUF2764 PF10962.8 EGO57032.1 - 0.0062 16.1 0.1 0.01 15.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2764) Borrelia_rep PF03183.13 EGO57032.1 - 0.12 12.4 0.2 0.46 10.6 0.2 2.1 1 0 0 1 1 1 0 Borrelia repeat protein MFS_1 PF07690.16 EGO57033.1 - 3.6e-36 124.8 65.9 5.8e-29 101.1 39.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 EGO57034.1 - 1.1e-27 97.2 0.0 1.9e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Endotoxin_mid PF09131.10 EGO57035.1 - 0.059 13.1 0.0 0.11 12.1 0.0 1.4 2 0 0 2 2 2 0 Bacillus thuringiensis delta-Endotoxin, middle domain EamA PF00892.20 EGO57037.1 - 1e-17 64.6 23.4 1.2e-13 51.4 3.6 3.3 3 0 0 3 3 3 3 EamA-like transporter family FAD_binding_3 PF01494.19 EGO57037.1 - 1.6e-06 27.6 0.1 0.0014 18.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain GspH PF12019.8 EGO57037.1 - 0.15 12.5 0.5 0.48 10.9 0.5 1.9 1 1 0 1 1 1 0 Type II transport protein GspH ZapB PF06005.12 EGO57038.1 - 0.023 15.1 3.7 0.023 15.1 3.7 2.1 2 0 0 2 2 2 0 Cell division protein ZapB SlyX PF04102.12 EGO57038.1 - 0.025 15.2 0.7 0.069 13.8 0.7 1.7 1 0 0 1 1 1 0 SlyX Pox_A11 PF05061.13 EGO57038.1 - 0.065 12.5 0.1 0.094 12.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein NPV_P10 PF05531.12 EGO57038.1 - 0.068 13.6 1.7 0.13 12.7 1.7 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 EGO57038.1 - 1.1 9.7 5.8 2.1 8.8 1.3 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) PNP_UDP_1 PF01048.20 EGO57040.1 - 4.3e-06 26.2 0.0 0.0047 16.2 0.2 3.0 1 1 1 2 2 2 2 Phosphorylase superfamily TPR_12 PF13424.6 EGO57041.1 - 2.9e-17 62.7 0.8 3.8e-11 43.1 0.1 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGO57041.1 - 4e-12 45.6 6.9 0.0018 18.0 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGO57041.1 - 7.9e-05 23.1 0.1 0.011 16.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat NACHT PF05729.12 EGO57041.1 - 0.00027 20.9 0.0 0.0013 18.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain TPR_14 PF13428.6 EGO57041.1 - 0.00096 19.8 0.1 2.4 9.2 0.1 5.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGO57041.1 - 0.0011 18.9 1.4 0.74 10.1 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGO57041.1 - 0.0012 18.9 0.6 0.67 10.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGO57041.1 - 0.0016 17.9 0.3 0.047 13.1 0.4 2.4 2 0 0 2 2 2 1 MalT-like TPR region TPR_1 PF00515.28 EGO57041.1 - 0.0034 17.1 1.9 5.1 7.1 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGO57041.1 - 0.0063 17.1 0.0 15 6.4 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat NB-ARC PF00931.22 EGO57041.1 - 0.0067 15.6 0.0 0.91 8.7 0.0 2.6 3 0 0 3 3 3 1 NB-ARC domain TPR_7 PF13176.6 EGO57041.1 - 0.019 15.0 1.4 27 5.1 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA_25 PF13481.6 EGO57041.1 - 0.042 13.4 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain TPR_20 PF14561.6 EGO57041.1 - 0.047 14.0 1.8 0.63 10.4 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO57041.1 - 0.12 13.0 0.1 55 4.7 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat GP57 PF17594.2 EGO57043.1 - 0.012 15.3 1.7 0.026 14.3 1.7 1.5 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 HsbA PF12296.8 EGO57043.1 - 0.069 13.6 2.4 0.13 12.6 2.4 1.5 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Mer2 PF09074.10 EGO57043.1 - 0.075 12.8 5.1 0.12 12.2 1.8 2.0 1 1 1 2 2 2 0 Mer2 Nucleo_P87 PF07267.11 EGO57043.1 - 0.12 11.2 5.7 0.16 10.8 5.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF883 PF05957.13 EGO57043.1 - 0.17 12.5 4.0 0.27 11.9 0.8 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3573 PF12097.8 EGO57043.1 - 0.26 10.1 0.7 0.35 9.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) RRN3 PF05327.11 EGO57043.1 - 0.36 9.3 7.6 0.49 8.9 7.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 EGO57043.1 - 0.86 8.9 8.3 1.1 8.5 8.3 1.0 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 EGO57043.1 - 2.9 7.6 11.5 4 7.1 11.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4611 PF15387.6 EGO57043.1 - 6 7.2 13.8 8.1 6.7 9.2 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4611) Aegerolysin PF06355.13 EGO57044.1 - 3.6e-44 150.0 0.0 4.5e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Aegerolysin POB3_N PF17292.2 EGO57044.1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.5 1 1 0 1 1 1 0 POB3-like N-terminal PH domain CPSF73-100_C PF11718.8 EGO57047.1 - 1.5e-87 292.7 0.0 2.3e-87 292.1 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EGO57047.1 - 7.6e-30 103.4 0.0 2e-29 102.1 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.27 EGO57047.1 - 4.7e-19 69.2 0.3 8.7e-19 68.3 0.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EGO57047.1 - 3.1e-17 62.7 0.1 4.8e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 EGO57047.1 - 3e-11 43.1 0.1 5.7e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EGO57047.1 - 1.1e-06 28.4 0.3 2.7e-06 27.0 0.3 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGO57047.1 - 1.5e-05 25.0 0.0 4e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EGO57047.1 - 0.14 11.3 0.6 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 Putative beta-lactamase-like family TAF4 PF05236.14 EGO57048.1 - 3e-27 96.1 0.6 9.5e-24 84.6 0.5 3.7 3 1 1 4 4 4 2 Transcription initiation factor TFIID component TAF4 family IU_nuc_hydro PF01156.19 EGO57049.1 - 9.5e-09 35.2 0.0 5.4e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase HMG_box PF00505.19 EGO57050.1 - 6.7e-21 74.5 1.7 1.4e-20 73.5 1.7 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO57050.1 - 1.7e-06 28.5 0.5 1.1e-05 25.9 0.5 2.3 2 0 0 2 2 2 1 HMG-box domain TIP49 PF06068.13 EGO57051.1 - 6.8e-167 555.0 0.1 8.6e-167 554.7 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EGO57051.1 - 5.8e-27 93.6 0.4 1.8e-26 92.1 0.2 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 EGO57051.1 - 7.3e-11 42.6 0.3 6e-07 29.9 0.2 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGO57051.1 - 1.2e-09 38.1 0.1 4.1e-07 29.9 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGO57051.1 - 0.00021 21.8 0.1 0.003 18.0 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGO57051.1 - 0.00025 21.3 0.3 0.32 11.2 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EGO57051.1 - 0.0027 17.9 0.6 0.0071 16.6 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGO57051.1 - 0.0049 16.9 0.1 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EGO57051.1 - 0.0079 16.5 4.2 0.2 12.0 4.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGO57051.1 - 0.008 15.8 0.2 0.038 13.6 0.1 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGO57051.1 - 0.0098 15.3 0.1 0.35 10.2 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 EGO57051.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 EGO57051.1 - 0.026 13.8 0.2 0.065 12.5 0.2 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 EGO57051.1 - 0.027 15.0 0.1 0.07 13.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGO57051.1 - 0.027 14.2 0.1 0.059 13.1 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EGO57051.1 - 0.032 13.9 0.1 0.87 9.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.9 EGO57051.1 - 0.043 13.0 0.1 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 EGO57051.1 - 0.068 12.7 0.1 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 EGO57051.1 - 0.12 12.1 0.3 3 7.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGO57051.1 - 0.18 11.7 0.1 0.57 10.1 0.1 1.8 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 EGO57051.1 - 0.39 10.0 2.7 0.55 9.5 0.1 2.4 3 0 0 3 3 3 0 KaiC ResIII PF04851.15 EGO57051.1 - 2.3 8.2 4.2 16 5.4 0.1 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Dynactin PF12455.8 EGO57052.1 - 2.5e-115 384.6 4.7 2.5e-115 384.6 4.7 4.3 4 2 2 6 6 6 1 Dynein associated protein CAP_GLY PF01302.25 EGO57052.1 - 9.3e-24 83.2 0.4 1.8e-23 82.4 0.4 1.5 1 0 0 1 1 1 1 CAP-Gly domain DUF2353 PF09789.9 EGO57052.1 - 0.00024 20.6 27.4 0.00024 20.6 27.4 4.7 2 2 1 4 4 4 2 Uncharacterized coiled-coil protein (DUF2353) HET PF06985.11 EGO57053.1 - 3.5e-27 95.5 0.2 6.4e-27 94.7 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4861 PF16153.5 EGO57054.1 - 0.24 10.4 4.4 0.19 10.7 2.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4861) SRP19 PF01922.17 EGO57055.1 - 5.8e-33 113.7 0.0 9.6e-33 113.0 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein zf-CCCH PF00642.24 EGO57056.1 - 0.025 14.5 5.1 0.025 14.5 5.1 2.6 2 1 1 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TSC22 PF01166.18 EGO57056.1 - 0.068 13.5 0.8 9.9 6.6 0.1 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family Jnk-SapK_ap_N PF09744.9 EGO57056.1 - 0.23 11.7 3.1 0.42 10.8 3.1 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 YabA PF06156.13 EGO57056.1 - 0.48 11.1 2.8 2.1 9.0 1.9 2.5 2 1 0 2 2 2 0 Initiation control protein YabA zf_CCCH_4 PF18345.1 EGO57056.1 - 1.2 9.3 6.2 6.8 6.9 2.5 3.0 2 0 0 2 2 2 0 Zinc finger domain Apt1 PF10351.9 EGO57056.1 - 1.8 7.3 5.8 0.21 10.4 1.5 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain Torus PF16131.5 EGO57056.1 - 4.4 8.1 11.0 0.37 11.5 1.6 2.7 1 1 1 2 2 2 0 Torus domain OMPdecase PF00215.24 EGO57057.1 - 1.3e-101 338.9 0.1 1.6e-101 338.7 0.1 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Fungal_trans PF04082.18 EGO57058.1 - 7.8e-08 31.7 0.0 1.6e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO57058.1 - 5.9e-07 29.5 11.2 1e-06 28.8 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FlaF PF07309.11 EGO57059.1 - 0.12 12.4 2.2 20 5.2 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein FlaF Arfaptin PF06456.13 EGO57059.1 - 0.15 11.6 2.7 0.28 10.7 2.7 1.3 1 0 0 1 1 1 0 Arfaptin-like domain RRM_1 PF00076.22 EGO57061.1 - 4.7e-43 144.9 0.9 1.2e-19 69.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EGO57061.1 - 9.9e-24 84.2 0.0 3.5e-23 82.5 0.0 2.0 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 EGO57061.1 - 0.00057 19.9 0.1 0.12 12.4 0.0 2.8 2 0 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.5 EGO57061.1 - 0.00059 19.7 0.0 0.25 11.2 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EGO57061.1 - 0.0056 16.8 0.1 2 8.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 EGO57061.1 - 0.0077 16.5 0.1 0.46 10.7 0.1 3.3 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 EGO57061.1 - 0.018 14.6 0.0 0.078 12.6 0.0 1.9 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGO57061.1 - 0.02 14.9 0.0 2.2 8.3 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Cyt-b5 PF00173.28 EGO57062.1 - 4.3e-16 58.8 2.9 4.9e-16 58.6 0.1 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EGO57062.1 - 6.1e-12 46.0 18.1 1.3e-11 45.0 18.1 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 EGO57062.1 - 0.014 15.6 1.2 0.027 14.7 0.1 1.9 2 0 0 2 2 2 0 Anthranilate synthase component I, N terminal region COX14 PF14880.6 EGO57062.1 - 0.022 14.6 0.5 0.056 13.3 0.2 1.8 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Het-C PF07217.11 EGO57063.1 - 1.8e-257 855.4 0.0 2.6e-257 854.9 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C HET PF06985.11 EGO57064.1 - 1.9e-29 102.9 0.0 5.4e-29 101.4 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PP2C PF00481.21 EGO57065.1 - 5.5e-36 124.5 0.0 2.6e-29 102.7 0.0 3.0 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 EGO57065.1 - 0.0035 17.0 0.0 0.02 14.5 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C BTB PF00651.31 EGO57066.1 - 0.046 13.9 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 BTB/POZ domain FTR1 PF03239.14 EGO57067.1 - 2e-72 243.9 9.4 1.9e-48 165.2 7.2 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family DUF4293 PF14126.6 EGO57067.1 - 0.0058 16.9 0.7 3.3 7.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4293) DUF4231 PF14015.6 EGO57067.1 - 0.024 15.1 0.2 0.024 15.1 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF5453 PF17534.2 EGO57067.1 - 1 9.3 3.9 0.6 10.0 0.5 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5453) Cu-oxidase_2 PF07731.14 EGO57068.1 - 2e-46 157.1 8.8 4.8e-42 142.9 1.3 2.7 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGO57068.1 - 5e-45 152.3 3.0 6.1e-42 142.4 0.2 3.3 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 EGO57068.1 - 1.5e-35 122.7 0.7 6.8e-31 107.5 0.1 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 EGO57068.1 - 0.00032 20.8 0.0 3.1 7.9 0.0 3.8 4 1 0 4 4 4 2 Cupredoxin-like domain DUF4297 PF14130.6 EGO57069.1 - 0.053 13.6 6.9 0.064 13.4 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4297) SpoU_methylase PF00588.19 EGO57069.1 - 0.11 12.7 0.7 0.15 12.3 0.7 1.2 1 0 0 1 1 1 0 SpoU rRNA Methylase family SPOUT_MTase PF02590.17 EGO57069.1 - 0.12 12.3 3.6 0.17 11.9 3.6 1.1 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase SSP160 PF06933.11 EGO57069.1 - 2.3 6.3 3.8 2.5 6.2 3.8 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Aminotran_1_2 PF00155.21 EGO57070.1 - 1.4e-36 126.5 0.0 1.8e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II VWA PF00092.28 EGO57071.1 - 3.2e-06 27.5 0.0 9.7e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGO57071.1 - 0.011 16.3 0.1 0.045 14.4 0.0 2.2 2 1 0 2 2 2 0 von Willebrand factor type A domain DUF3824 PF12868.7 EGO57072.1 - 0.00058 20.6 31.0 0.0014 19.3 28.5 2.5 2 0 0 2 2 2 1 Domain of unknwon function (DUF3824) TAF PF02969.17 EGO57072.1 - 0.018 15.2 0.3 0.04 14.1 0.3 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Serglycin PF04360.12 EGO57072.1 - 0.022 14.7 5.0 0.022 14.7 5.0 3.5 3 1 1 4 4 4 0 Serglycin HTH_7 PF02796.15 EGO57072.1 - 0.031 14.3 0.0 0.31 11.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase SOBP PF15279.6 EGO57072.1 - 0.3 11.7 30.7 0.46 11.1 30.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Glycos_transf_1 PF00534.20 EGO57073.1 - 7.8e-35 119.9 0.0 2e-34 118.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGO57073.1 - 4.6e-15 56.2 0.0 1.8e-14 54.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGO57073.1 - 2.5e-14 53.7 0.0 4.7e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EGO57073.1 - 5.9e-06 26.8 0.0 1.1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EGO57073.1 - 0.00023 21.5 0.0 0.00044 20.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 EGO57073.1 - 0.0023 18.0 0.1 0.88 9.6 0.1 2.4 1 1 0 1 1 1 1 ALG11 mannosyltransferase N-terminus PAP2 PF01569.21 EGO57074.1 - 3.2e-19 69.0 4.3 7e-19 67.9 4.3 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EGO57074.1 - 0.00029 20.6 4.1 0.0007 19.3 4.1 1.7 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 EGO57074.1 - 0.23 11.6 0.2 0.23 11.6 0.2 1.9 2 0 0 2 2 2 0 Divergent PAP2 family JmjC PF02373.22 EGO57075.1 - 4.6e-36 123.7 0.4 4.6e-36 123.7 0.4 2.9 3 0 0 3 3 3 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 EGO57075.1 - 3.8e-21 75.3 3.5 7.5e-21 74.4 3.5 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EGO57075.1 - 1.4e-20 73.3 3.3 3e-20 72.3 3.3 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.17 EGO57075.1 - 6.9e-13 48.3 0.9 1.9e-12 46.9 0.9 1.8 1 0 0 1 1 1 1 jmjN domain DUF4440 PF14534.6 EGO57076.1 - 0.00046 20.5 0.0 0.00064 20.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 EGO57076.1 - 0.11 13.2 0.0 0.19 12.4 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain HET PF06985.11 EGO57077.1 - 2.6e-15 57.0 1.0 5.5e-07 30.0 0.2 3.2 2 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) DNA_mis_repair PF01119.19 EGO57077.1 - 0.043 13.5 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain HET PF06985.11 EGO57078.1 - 5.2e-37 127.4 0.9 9.9e-37 126.5 0.9 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Beta-lactamase PF00144.24 EGO57079.1 - 1.7 7.8 5.3 6.8 5.8 5.2 1.8 1 1 0 1 1 1 0 Beta-lactamase AA_permease PF00324.21 EGO57080.1 - 1.9e-143 478.5 41.5 2.2e-143 478.3 41.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO57080.1 - 8.1e-36 123.8 46.9 1.1e-35 123.3 46.9 1.1 1 0 0 1 1 1 1 Amino acid permease SVM_signal PF12113.8 EGO57080.1 - 5.7 6.9 8.1 2.3 8.2 1.3 2.8 2 0 0 2 2 2 0 SVM protein signal sequence Hce2 PF14856.6 EGO57082.1 - 9.1e-25 86.9 0.0 1.2e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor HP_OMP_2 PF02521.14 EGO57082.1 - 0.023 13.6 0.0 0.028 13.3 0.0 1.1 1 0 0 1 1 1 0 Putative outer membrane protein Hce2 PF14856.6 EGO57083.1 - 6.1e-06 26.5 0.1 5.2e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor LVIVD PF08309.11 EGO57084.1 - 5.3e-09 35.3 1.7 0.17 11.2 0.1 5.3 5 0 0 5 5 5 5 LVIVD repeat Dicty_REP PF05086.12 EGO57085.1 - 0.2 9.6 0.2 0.26 9.2 0.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LRR_4 PF12799.7 EGO57085.1 - 2.7 8.5 0.0 2.7 8.5 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Septin PF00735.18 EGO57087.1 - 3.7e-114 380.8 1.1 4.5e-114 380.5 1.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGO57087.1 - 3.5e-08 33.5 0.1 7.8e-08 32.4 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGO57087.1 - 1.6e-06 27.6 0.0 2.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EGO57087.1 - 1.7e-06 28.0 0.4 4.2e-05 23.5 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EGO57087.1 - 3.4e-05 23.5 0.8 0.0046 16.5 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EGO57087.1 - 0.00032 20.8 0.4 0.88 9.6 0.0 2.7 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.6 EGO57087.1 - 0.00074 19.9 0.0 0.018 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGO57087.1 - 0.0032 17.7 0.0 0.0079 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGO57087.1 - 0.0036 16.9 0.1 0.021 14.3 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 EGO57087.1 - 0.0053 17.3 0.6 0.011 16.3 0.4 1.8 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 EGO57087.1 - 0.0064 15.7 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Gtr1_RagA PF04670.12 EGO57087.1 - 0.0096 15.3 0.2 0.14 11.4 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_23 PF13476.6 EGO57087.1 - 0.025 15.1 0.5 0.069 13.6 0.4 1.6 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 EGO57087.1 - 0.031 14.5 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGO57087.1 - 0.053 13.1 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Ras family FtsK_SpoIIIE PF01580.18 EGO57087.1 - 0.061 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 EGO57087.1 - 0.078 12.1 1.3 0.18 10.9 1.3 1.8 1 1 0 1 1 1 0 G-protein alpha subunit Microtub_bd PF16796.5 EGO57087.1 - 0.086 12.8 0.1 0.62 10.0 0.0 2.2 2 0 0 2 2 2 0 Microtubule binding AAA_29 PF13555.6 EGO57087.1 - 0.2 11.4 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L32p PF01783.23 EGO57088.1 - 7e-15 55.0 6.1 1.1e-14 54.4 6.1 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family RecR PF02132.15 EGO57088.1 - 0.025 14.1 0.5 0.042 13.4 0.5 1.3 1 0 0 1 1 1 0 RecR protein ANAPC4_WD40 PF12894.7 EGO57089.1 - 3.2e-14 53.0 1.3 0.0075 16.5 0.3 4.3 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO57089.1 - 5e-14 52.5 11.6 0.00066 20.4 0.3 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.11 EGO57089.1 - 2.5e-05 24.2 0.0 0.0083 16.0 0.0 2.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 EGO57089.1 - 0.0014 18.4 0.3 0.024 14.4 0.0 2.2 2 0 0 2 2 2 1 TUP1-like enhancer of split Nup160 PF11715.8 EGO57089.1 - 0.0051 15.5 0.2 0.43 9.2 0.1 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGO57089.1 - 0.023 13.5 0.0 0.12 11.1 0.0 2.1 2 2 1 3 3 3 0 Nup133 N terminal like Nbas_N PF15492.6 EGO57089.1 - 0.028 13.7 0.0 2.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 EGO57089.1 - 0.033 13.1 3.8 0.42 9.5 0.1 2.6 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 EGO57089.1 - 0.8 10.3 6.5 0.95 10.0 0.4 3.1 2 0 0 2 2 2 0 PQQ-like domain Glyco_hydro_65C PF03633.15 EGO57092.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.5 1 1 1 2 2 2 0 Glycosyl hydrolase family 65, C-terminal domain Pkinase PF00069.25 EGO57095.1 - 1.1e-50 172.5 0.0 1.1e-34 120.0 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57095.1 - 6e-21 74.9 3.6 2.5e-18 66.3 3.6 3.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO57095.1 - 7.5e-05 22.2 0.0 0.00021 20.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGO57095.1 - 0.00079 18.3 0.1 0.0027 16.6 0.0 1.9 2 1 0 2 2 2 1 Fungal protein kinase adh_short PF00106.25 EGO57096.1 - 3.7e-43 147.3 0.1 1.2e-32 113.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO57096.1 - 1.3e-34 119.8 0.0 1e-30 107.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO57096.1 - 5.6e-06 26.4 0.1 2.5e-05 24.3 0.1 2.1 1 1 0 1 1 1 1 KR domain ApbA PF02558.16 EGO57096.1 - 0.01 15.5 0.0 0.017 14.7 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 EGO57096.1 - 0.029 14.6 0.0 0.35 11.1 0.0 2.4 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EGO57096.1 - 0.065 12.7 0.1 2.3 7.6 0.0 2.7 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family ThiF PF00899.21 EGO57097.1 - 6.9e-76 254.8 0.1 1e-75 254.2 0.1 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 EGO57097.1 - 1.1e-24 86.8 2.1 1.4e-24 86.5 0.7 2.0 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 EGO57097.1 - 1.7e-06 28.2 3.7 8.1e-05 22.7 2.5 2.7 1 1 1 2 2 2 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EGO57097.1 - 0.00021 21.7 0.6 0.00053 20.4 0.1 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EGO57097.1 - 0.0043 17.1 0.1 0.0099 15.9 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EGO57097.1 - 0.012 16.2 0.2 0.38 11.4 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase E2_bind PF08825.10 EGO57097.1 - 0.062 13.5 0.8 0.42 10.8 0.1 2.2 2 0 0 2 2 2 0 E2 binding domain Semialdhyde_dh PF01118.24 EGO57097.1 - 0.083 13.3 0.1 0.27 11.7 0.1 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Topoisom_bac PF01131.20 EGO57097.1 - 0.094 11.7 0.5 0.2 10.6 0.5 1.5 1 0 0 1 1 1 0 DNA topoisomerase Q_salvage PF10343.9 EGO57098.1 - 7.1e-131 435.9 0.0 9e-131 435.6 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DNA_pol_delta_4 PF04081.13 EGO57099.1 - 1.3e-45 154.9 2.2 1.3e-45 154.9 2.2 2.2 1 1 1 2 2 2 1 DNA polymerase delta, subunit 4 TFIIF_alpha PF05793.12 EGO57099.1 - 0.018 13.7 18.2 0.024 13.2 18.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 EGO57099.1 - 0.11 10.8 10.8 0.13 10.6 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EGO57099.1 - 0.19 10.4 9.2 0.2 10.4 9.2 1.1 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.9 EGO57099.1 - 0.29 11.2 15.9 0.47 10.6 15.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Borrelia_P83 PF05262.11 EGO57099.1 - 0.49 8.8 20.1 0.59 8.6 20.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Endostatin PF06482.11 EGO57099.1 - 0.7 9.3 10.3 1 8.7 10.3 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin RR_TM4-6 PF06459.12 EGO57099.1 - 1.1 9.1 20.5 1.5 8.5 20.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 EGO57099.1 - 1.3 8.0 11.3 1.7 7.6 11.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GAGA_bind PF06217.12 EGO57099.1 - 1.9 8.7 15.0 2.8 8.1 15.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Asp-B-Hydro_N PF05279.11 EGO57099.1 - 3.5 7.6 22.1 5.2 7.1 22.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Red1 PF07964.11 EGO57099.1 - 4.9 5.3 20.8 5.4 5.1 20.8 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Caprin-1_C PF12287.8 EGO57099.1 - 5 7.2 7.5 6 6.9 7.5 1.2 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term DUF4484 PF14831.6 EGO57099.1 - 6.2 6.8 12.8 41 4.1 12.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) DUF5427 PF10310.9 EGO57099.1 - 8.5 5.2 22.5 11 4.9 22.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) HTH_psq PF05225.16 EGO57100.1 - 6.8e-16 57.7 0.1 1.2e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 EGO57100.1 - 4.7e-06 26.5 0.1 0.007 16.4 0.0 2.4 2 0 0 2 2 2 2 Tc5 transposase DNA-binding domain Cwf_Cwc_15 PF04889.12 EGO57100.1 - 0.003 17.3 19.8 0.0053 16.5 19.8 1.5 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein TnsD PF15978.5 EGO57100.1 - 0.054 12.5 0.4 0.091 11.7 0.0 1.5 2 0 0 2 2 2 0 Tn7-like transposition protein D Dicty_REP PF05086.12 EGO57100.1 - 8.6 4.2 13.6 18 3.1 13.6 1.5 1 1 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4680 PF15730.5 EGO57100.1 - 9 6.6 11.1 0.33 11.3 3.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) CFEM PF05730.11 EGO57101.1 - 2.6e-12 46.7 5.4 5.1e-12 45.7 5.4 1.5 1 0 0 1 1 1 1 CFEM domain TRAP_alpha PF03896.16 EGO57102.1 - 0.022 14.0 3.5 0.029 13.6 3.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tim54 PF11711.8 EGO57102.1 - 0.37 9.5 6.1 0.52 9.1 6.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 EGO57102.1 - 0.58 8.9 6.2 0.68 8.6 6.2 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 EGO57102.1 - 0.8 7.8 14.9 0.99 7.5 14.9 1.0 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 EGO57102.1 - 3.1 6.9 6.2 3.8 6.6 6.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIIAH PF12685.7 EGO57102.1 - 5.3 6.8 12.3 7 6.4 12.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein FYDLN_acid PF09538.10 EGO57102.1 - 9.1 7.0 17.3 15 6.3 17.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SDA1 PF05285.12 EGO57102.1 - 9.5 5.5 17.1 12 5.2 17.1 1.1 1 0 0 1 1 1 0 SDA1 HET PF06985.11 EGO57103.1 - 7.1e-35 120.5 0.5 1.3e-34 119.7 0.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3669 PF12417.8 EGO57104.1 - 4.4e-26 90.9 0.0 1e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 Zinc finger protein DUF3669 PF12417.8 EGO57105.1 - 4.7e-10 39.5 0.2 8.4e-10 38.7 0.2 1.4 1 0 0 1 1 1 1 Zinc finger protein Ribonuc_red_lgC PF02867.15 EGO57106.1 - 2.6e-192 640.0 0.0 3.3e-192 639.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EGO57106.1 - 2.2e-23 82.0 0.0 5.4e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EGO57106.1 - 4.9e-17 62.3 0.0 1.1e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain TatD_DNase PF01026.21 EGO57107.1 - 8.3e-44 149.9 0.0 1.3e-38 132.8 0.0 2.3 2 1 0 2 2 2 2 TatD related DNase DUF908 PF06012.12 EGO57107.1 - 0.62 9.4 5.5 0.12 11.8 1.5 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Presenilin PF01080.17 EGO57107.1 - 3.7 6.2 6.2 5.8 5.6 6.2 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 EGO57107.1 - 5.8 4.9 5.6 8.9 4.3 5.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CENP-N PF05238.13 EGO57108.1 - 1e-155 519.1 0.0 1.3e-155 518.8 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.15 EGO57109.1 - 6.8e-13 48.5 11.8 1.5e-12 47.4 11.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper XhlA PF10779.9 EGO57109.1 - 0.003 17.7 2.2 0.003 17.7 2.2 1.8 2 0 0 2 2 2 1 Haemolysin XhlA bZIP_1 PF00170.21 EGO57109.1 - 0.0052 16.8 14.1 0.011 15.8 10.1 1.7 1 1 1 2 2 2 2 bZIP transcription factor DUF4349 PF14257.6 EGO57109.1 - 0.029 13.8 2.7 0.023 14.2 1.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) TSC22 PF01166.18 EGO57109.1 - 0.031 14.6 0.1 0.066 13.5 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family LCD1 PF09798.9 EGO57109.1 - 0.04 12.4 3.2 0.044 12.3 3.2 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein GIT_CC PF16559.5 EGO57109.1 - 0.089 12.7 0.5 0.18 11.7 0.5 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_Maf PF03131.17 EGO57109.1 - 0.37 11.3 8.1 0.17 12.4 5.5 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor V_ATPase_I PF01496.19 EGO57109.1 - 2.5 5.9 6.6 3.2 5.5 6.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_60s PF00428.19 EGO57109.1 - 9.3 6.9 22.1 0.069 13.7 12.1 2.5 1 1 1 2 2 2 0 60s Acidic ribosomal protein zf-Nse PF11789.8 EGO57112.1 - 0.017 15.0 0.2 0.053 13.3 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ECH_1 PF00378.20 EGO57113.1 - 3.6e-23 82.2 0.0 4.4e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGO57113.1 - 8.8e-10 38.6 0.0 1.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EGO57113.1 - 0.0059 16.6 0.0 4.1 7.4 0.0 2.3 2 1 0 2 2 2 2 Peptidase family S49 ATG27 PF09451.10 EGO57114.1 - 1.2e-88 297.4 0.1 1.9e-88 296.8 0.1 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Pro-rich PF15240.6 EGO57114.1 - 0.058 13.7 1.7 0.097 12.9 1.7 1.2 1 0 0 1 1 1 0 Proline-rich LRR_4 PF12799.7 EGO57116.1 - 3e-27 94.2 35.5 1e-07 32.1 2.3 8.5 6 2 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGO57116.1 - 4.4e-22 77.6 37.6 1.2e-07 31.4 0.6 7.1 4 2 4 8 8 8 6 Leucine rich repeat LRR_9 PF14580.6 EGO57116.1 - 1.4e-06 27.9 11.5 0.048 13.2 1.5 4.5 3 2 1 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 EGO57116.1 - 0.46 10.7 23.9 1.5 9.1 0.1 8.4 9 0 0 9 9 9 0 Leucine Rich repeat SCIMP PF15050.6 EGO57116.1 - 0.96 9.9 4.9 1.8 9.0 0.3 3.1 2 0 0 2 2 2 0 SCIMP protein GerA PF03323.13 EGO57117.1 - 0.11 10.9 1.5 0.1 11.1 1.5 1.0 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein HOK_GEF PF01848.16 EGO57117.1 - 0.15 11.5 5.3 0.18 11.2 5.3 1.2 1 0 0 1 1 1 0 Hok/gef family IPK PF03770.16 EGO57118.1 - 1.9e-55 187.8 0.0 4.3e-55 186.6 0.0 1.6 2 0 0 2 2 2 1 Inositol polyphosphate kinase Pam17 PF08566.10 EGO57118.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 SelP_N PF04592.14 EGO57118.1 - 0.87 8.9 15.3 4.1 6.7 15.3 2.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Hexapep PF00132.24 EGO57120.1 - 1.9e-06 27.4 2.4 0.0014 18.3 0.8 3.2 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EGO57120.1 - 7.2e-05 21.9 2.9 0.0011 18.0 2.9 2.0 1 1 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 EGO57120.1 - 8.1e-05 23.0 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EGO57120.1 - 0.00081 19.0 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 EGO57120.1 - 0.0025 16.0 1.6 0.0079 14.4 1.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EGO57120.1 - 0.018 14.8 4.3 0.29 10.9 1.9 3.1 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase NOA36 PF06524.12 EGO57120.1 - 0.33 10.2 12.0 0.49 9.7 12.0 1.3 1 0 0 1 1 1 0 NOA36 protein Spt20 PF12090.8 EGO57123.1 - 5.3e-32 111.3 0.0 5.3e-32 111.3 0.0 8.8 4 3 4 8 8 8 1 Spt20 family zf-C2H2 PF00096.26 EGO57128.1 - 1.3e-07 31.7 8.7 0.0029 18.0 1.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO57128.1 - 7.4e-05 23.3 5.7 0.17 12.8 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EGO57128.1 - 0.022 15.1 0.0 0.022 15.1 0.0 2.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EGO57128.1 - 0.028 14.9 2.0 0.028 14.9 2.0 2.7 3 0 0 3 3 3 0 Zinc-finger double domain FOXP-CC PF16159.5 EGO57128.1 - 0.053 14.1 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-Di19 PF05605.12 EGO57128.1 - 0.096 13.0 0.8 0.18 12.1 0.8 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 EGO57128.1 - 0.15 12.4 2.5 1 9.7 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding LRR_4 PF12799.7 EGO57130.1 - 0.035 14.5 3.8 38 4.9 0.2 4.4 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Col_cuticle_N PF01484.17 EGO57131.1 - 4.3 7.5 4.7 9.7 6.3 4.7 1.6 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Abp2 PF09441.10 EGO57132.1 - 4.7e-83 277.4 0.0 6.9e-83 276.9 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 Mito_carr PF00153.27 EGO57133.1 - 3e-52 174.5 5.1 1.3e-16 60.2 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.16 EGO57133.1 - 0.088 12.8 0.2 0.51 10.3 0.1 2.3 2 0 0 2 2 2 0 UcrQ family Mak10 PF04112.13 EGO57134.1 - 4.7e-59 198.7 0.0 1e-58 197.6 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.13 EGO57135.1 - 8.5e-21 73.7 2.9 8.5e-21 73.7 2.9 1.4 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16 PF00675.20 EGO57136.1 - 3e-18 66.2 0.0 4.4e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGO57136.1 - 5.3e-13 49.4 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 EGO57136.1 - 0.092 11.9 0.4 0.39 9.8 0.1 1.9 2 0 0 2 2 2 0 Peptidase M16C associated RNA_pol_Rpc82 PF05645.13 EGO57137.1 - 1.4e-70 238.0 3.3 6.8e-70 235.8 0.2 3.1 4 0 0 4 4 4 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 EGO57137.1 - 5.9e-22 77.5 0.9 1.4e-20 73.2 0.5 3.1 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TrmB PF01978.19 EGO57137.1 - 0.079 12.9 0.1 6 6.8 0.0 3.2 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB Mito_carr PF00153.27 EGO57138.1 - 5.2e-31 106.4 0.3 5.7e-14 51.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpc4 PF05132.14 EGO57139.1 - 0.0024 18.3 23.4 0.0029 18.0 23.4 1.1 1 0 0 1 1 1 1 RNA polymerase III RPC4 DUF2052 PF09747.9 EGO57139.1 - 0.072 13.2 17.3 0.073 13.2 17.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Tim54 PF11711.8 EGO57139.1 - 0.083 11.7 26.7 0.1 11.4 26.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 EGO57139.1 - 0.18 11.6 32.6 0.19 11.5 32.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4776 PF16003.5 EGO57139.1 - 0.4 9.6 35.5 0.39 9.6 35.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) CLN3 PF02487.17 EGO57139.1 - 0.54 9.2 15.7 0.65 9.0 15.7 1.0 1 0 0 1 1 1 0 CLN3 protein SpoIIP PF07454.11 EGO57139.1 - 0.54 9.7 27.3 0.61 9.5 27.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 EGO57139.1 - 0.65 10.1 16.2 0.8 9.8 16.2 1.2 1 0 0 1 1 1 0 DDHD domain RP-C_C PF11800.8 EGO57139.1 - 1.1 9.4 13.6 1.2 9.2 13.6 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region XRN_M PF17846.1 EGO57139.1 - 1.1 8.2 21.2 1.2 8.0 21.2 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Kei1 PF08552.11 EGO57139.1 - 1.1 9.1 6.4 1.3 8.9 6.4 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 CobT PF06213.12 EGO57139.1 - 1.6 8.1 13.6 1.9 7.8 13.6 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF5308 PF17233.2 EGO57139.1 - 1.7 8.9 9.0 2.5 8.3 9.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DUF4228 PF14009.6 EGO57139.1 - 1.7 9.0 18.4 1.8 8.9 18.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF2828 PF11443.8 EGO57139.1 - 1.7 6.7 32.1 1.8 6.5 32.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Vfa1 PF08432.10 EGO57139.1 - 2.2 8.6 49.0 3.6 7.9 49.0 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 UPF0565 PF10561.9 EGO57139.1 - 2.3 7.3 13.6 2.7 7.1 13.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF789 PF05623.12 EGO57139.1 - 2.6 7.7 15.0 2.9 7.5 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) PepSY_TM_like_2 PF16357.5 EGO57139.1 - 2.7 7.9 6.1 3.2 7.7 6.1 1.0 1 0 0 1 1 1 0 Putative PepSY_TM-like Striatin PF08232.12 EGO57139.1 - 3.1 8.4 31.4 3.5 8.2 31.4 1.1 1 0 0 1 1 1 0 Striatin family Endostatin PF06482.11 EGO57139.1 - 3.7 6.9 14.4 3.8 6.9 14.4 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Hid1 PF12722.7 EGO57139.1 - 3.9 5.5 14.8 4.2 5.4 14.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF913 PF06025.12 EGO57139.1 - 4.3 6.2 16.1 4.8 6.0 16.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF5427 PF10310.9 EGO57139.1 - 4.5 6.1 29.6 4.7 6.0 29.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SLC12 PF03522.15 EGO57139.1 - 4.5 6.2 27.9 4.8 6.1 27.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 CBP_BcsG PF11658.8 EGO57139.1 - 4.6 5.5 9.5 5.6 5.2 9.5 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Serinc PF03348.15 EGO57139.1 - 4.8 6.0 11.4 5.5 5.8 11.4 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) AAA_11 PF13086.6 EGO57139.1 - 4.8 6.9 27.3 5.1 6.8 27.3 1.0 1 0 0 1 1 1 0 AAA domain Folliculin PF11704.8 EGO57139.1 - 4.9 7.0 14.1 5.9 6.7 14.1 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Ctr PF04145.15 EGO57139.1 - 5 7.7 11.1 7.4 7.2 11.1 1.3 1 0 0 1 1 1 0 Ctr copper transporter family BORG_CEP PF14957.6 EGO57139.1 - 5.9 8.1 18.0 7 7.8 18.0 1.1 1 0 0 1 1 1 0 Cdc42 effector Zip PF02535.22 EGO57139.1 - 5.9 6.0 19.6 6.4 5.9 19.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter AAA_23 PF13476.6 EGO57139.1 - 8.6 6.8 34.8 12 6.3 34.8 1.3 1 0 0 1 1 1 0 AAA domain Actin PF00022.19 EGO57141.1 - 1.2e-18 66.9 0.0 1.1e-10 40.7 0.0 3.8 3 1 0 3 3 3 3 Actin GEN1_C PF18380.1 EGO57142.1 - 1e-29 103.5 0.0 1e-29 103.5 0.0 3.5 4 1 0 4 4 4 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 EGO57142.1 - 1.6e-25 89.3 0.0 3e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EGO57142.1 - 4.3e-07 30.3 0.0 9.3e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain UIM PF02809.20 EGO57142.1 - 3.3 7.8 7.7 0.54 10.3 1.9 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif Ribosomal_L26 PF16906.5 EGO57143.1 - 3.2e-40 136.5 2.5 4.2e-40 136.1 2.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EGO57143.1 - 8e-07 28.8 1.9 2.3e-06 27.3 1.5 1.9 2 0 0 2 2 2 1 KOW motif Get5_C PF18514.1 EGO57143.1 - 0.11 12.2 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Get5 C-terminal domain adh_short PF00106.25 EGO57144.1 - 5e-37 127.3 0.0 6.5e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO57144.1 - 1.7e-23 83.4 0.0 2.3e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EGO57144.1 - 8.2e-05 22.2 0.0 0.00018 21.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EGO57144.1 - 0.0002 21.3 0.2 0.00061 19.7 0.2 1.8 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGO57144.1 - 0.2 11.0 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Macoilin PF09726.9 EGO57145.1 - 0.25 9.8 7.4 0.16 10.5 2.5 2.1 2 0 0 2 2 2 0 Macoilin family Apt1 PF10351.9 EGO57145.1 - 2.7 6.7 6.2 10 4.9 0.1 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Pkinase PF00069.25 EGO57148.1 - 1.1e-69 234.8 0.0 1.5e-69 234.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57148.1 - 2.4e-36 125.4 0.0 6e-36 124.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO57148.1 - 2.1e-06 27.3 0.1 0.0012 18.2 0.0 2.4 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 EGO57148.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO57148.1 - 0.0065 16.4 1.4 0.013 15.4 0.0 2.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGO57148.1 - 0.0093 14.9 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EGO57148.1 - 0.024 14.3 0.1 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SWIB PF02201.18 EGO57149.1 - 8.1e-22 76.9 0.0 1.6e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Sfi1 PF08457.10 EGO57150.1 - 2.6e-144 481.9 75.0 2e-143 479.0 67.3 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein Cep57_MT_bd PF06657.13 EGO57150.1 - 0.15 12.6 1.7 0.23 11.9 0.1 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Synaphin PF05835.12 EGO57150.1 - 1.1 9.5 5.8 0.21 11.8 0.6 2.6 2 0 0 2 2 2 0 Synaphin protein CX9C PF16860.5 EGO57151.1 - 0.014 15.4 1.6 0.022 14.7 1.6 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 EGO57151.1 - 0.047 13.4 1.8 2.7 7.8 0.0 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UCR_hinge PF02320.16 EGO57151.1 - 0.047 13.9 0.8 0.074 13.3 0.8 1.4 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.13 EGO57151.1 - 0.049 13.8 2.7 0.62 10.3 2.7 2.1 1 1 1 2 2 2 0 CHCH domain tRNA-synt_1 PF00133.22 EGO57152.1 - 3.1e-227 755.6 0.1 4.4e-227 755.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGO57152.1 - 1.6e-25 89.9 0.0 5.1e-25 88.2 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGO57152.1 - 4.2e-16 58.7 0.0 6.3e-06 25.2 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EGO57152.1 - 0.022 14.1 0.0 0.08 12.3 0.0 1.9 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain Mo25 PF08569.11 EGO57153.1 - 2.3e-125 418.3 0.1 2.6e-125 418.1 0.1 1.0 1 0 0 1 1 1 1 Mo25-like Presenilin PF01080.17 EGO57154.1 - 5.6 5.6 9.9 8.3 5.1 9.9 1.2 1 0 0 1 1 1 0 Presenilin Ala_racemase_N PF01168.20 EGO57156.1 - 1.6e-23 83.6 0.0 1.9e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain FAD_SOX PF18371.1 EGO57156.1 - 0.075 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase PolyA_pol_arg_C PF12626.7 EGO57156.1 - 0.19 11.8 0.5 0.56 10.3 0.1 1.8 2 0 0 2 2 2 0 Polymerase A arginine-rich C-terminus Synaptobrevin PF00957.21 EGO57157.1 - 0.14 11.9 0.4 0.3 10.9 0.4 1.5 1 0 0 1 1 1 0 Synaptobrevin NAS PF03059.16 EGO57160.1 - 0.0052 16.2 0.5 0.084 12.2 0.1 2.1 2 0 0 2 2 2 1 Nicotianamine synthase protein Csc2 PF18320.1 EGO57160.1 - 0.1 11.5 0.3 0.18 10.7 0.3 1.4 1 0 0 1 1 1 0 Csc2 Crispr SpoIIIAH PF12685.7 EGO57160.1 - 2.2 8.1 6.7 5 6.9 1.8 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein tRNA-synt_2b PF00587.25 EGO57161.1 - 1.3e-17 64.4 0.0 2.1e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGO57161.1 - 1.3e-10 41.5 5.2 9.3e-10 38.7 5.2 2.1 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain BBP1_C PF15272.6 EGO57161.1 - 0.37 10.6 1.5 0.62 9.9 0.8 1.7 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal MS_channel PF00924.18 EGO57162.1 - 3.5e-21 75.7 2.8 6e-21 74.9 2.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.6 EGO57162.1 - 0.0023 18.3 0.1 0.006 17.0 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGO57162.1 - 0.0027 17.1 0.1 0.0057 16.1 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EGO57162.1 - 0.0072 15.8 0.2 0.017 14.7 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EGO57162.1 - 0.098 12.6 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain DUF1189 PF06691.11 EGO57162.1 - 0.18 11.3 8.2 0.36 10.4 3.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) PhyH PF05721.13 EGO57163.1 - 5.2e-13 49.7 0.0 6.6e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ERM PF00769.19 EGO57164.1 - 0.0034 17.2 25.4 0.0042 17.0 25.4 1.0 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF4559 PF15112.6 EGO57164.1 - 0.0091 15.7 6.2 0.0091 15.7 6.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4559) Fmp27_WPPW PF10359.9 EGO57164.1 - 0.015 14.2 10.5 0.017 14.0 10.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FapA PF03961.13 EGO57164.1 - 0.028 13.0 10.5 0.029 13.0 10.5 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A T3SSipB PF16535.5 EGO57164.1 - 0.047 14.2 11.4 0.057 13.9 11.4 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB eIF3_N PF09440.10 EGO57164.1 - 0.13 12.7 9.3 0.17 12.3 9.3 1.2 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain AAA_15 PF13175.6 EGO57164.1 - 0.2 11.3 6.6 0.26 11.0 6.6 1.2 1 0 0 1 1 1 0 AAA ATPase domain Phage_GPO PF05929.11 EGO57164.1 - 0.21 11.2 9.6 0.24 11.0 9.6 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TMEM247 PF15444.6 EGO57164.1 - 0.26 11.3 8.0 0.31 11.1 8.0 1.0 1 0 0 1 1 1 0 Transmembrane protein 247 VSG_B PF13206.6 EGO57164.1 - 0.27 10.4 14.7 0.32 10.2 14.7 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF4121 PF13497.6 EGO57164.1 - 0.65 9.1 5.4 0.56 9.3 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4121) DUF3417 PF11897.8 EGO57164.1 - 0.69 10.4 6.2 1.4 9.4 6.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3417) V_ATPase_I PF01496.19 EGO57164.1 - 1.2 7.0 9.0 1.3 6.8 9.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.8 EGO57164.1 - 1.2 8.3 14.2 1.5 8.1 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) BBS1 PF14779.6 EGO57164.1 - 2 7.8 6.2 2.2 7.6 6.2 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 CDC45 PF02724.14 EGO57164.1 - 2.5 6.3 13.5 2.7 6.2 13.5 1.0 1 0 0 1 1 1 0 CDC45-like protein MCM3AP_GANP PF16769.5 EGO57164.1 - 2.7 6.1 13.0 3.2 5.9 13.0 1.0 1 0 0 1 1 1 0 MCM3AP domain of GANP DDHD PF02862.17 EGO57164.1 - 2.7 8.1 5.2 3.1 7.9 5.2 1.1 1 0 0 1 1 1 0 DDHD domain AAA_11 PF13086.6 EGO57164.1 - 2.7 7.7 13.4 3.2 7.5 13.4 1.0 1 0 0 1 1 1 0 AAA domain CCDC-167 PF15188.6 EGO57164.1 - 4.1 7.8 17.2 6.4 7.2 17.1 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3810 PF12725.7 EGO57164.1 - 5 6.4 5.3 5.9 6.1 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Presenilin PF01080.17 EGO57164.1 - 6.5 5.4 11.9 7.4 5.2 11.9 1.0 1 0 0 1 1 1 0 Presenilin TMPIT PF07851.13 EGO57164.1 - 6.9 5.8 12.5 8.6 5.5 12.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein Vfa1 PF08432.10 EGO57164.1 - 9.3 6.5 20.8 12 6.2 20.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA12 PF10443.9 EGO57166.1 - 7.1e-177 588.6 1.7 9.3e-177 588.2 1.7 1.1 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.22 EGO57166.1 - 5.2e-10 39.0 0.0 1.7e-06 27.7 0.0 3.5 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.9 EGO57166.1 - 0.00029 20.9 0.0 0.00098 19.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2487) ATPase_2 PF01637.18 EGO57166.1 - 0.002 18.1 0.1 0.17 11.8 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea DUF3128 PF11326.8 EGO57167.1 - 1.2e-28 99.3 2.7 2.3e-28 98.4 2.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DLH PF01738.18 EGO57168.1 - 3.5e-20 72.5 0.0 1.4e-19 70.5 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EGO57168.1 - 0.00066 20.4 0.8 0.00083 20.0 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EGO57168.1 - 0.0008 19.1 0.0 0.0026 17.4 0.0 1.7 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 EGO57168.1 - 0.015 15.2 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal HSP70 PF00012.20 EGO57169.1 - 2.1e-262 871.7 5.3 2.4e-262 871.5 5.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGO57169.1 - 4.6e-18 65.1 0.1 8.6e-17 60.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EGO57169.1 - 0.00074 19.3 0.0 0.0026 17.5 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EGO57169.1 - 0.005 17.2 1.5 8.7 6.8 0.0 3.5 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 EGO57169.1 - 0.019 14.2 0.1 0.039 13.2 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 EGO57169.1 - 0.036 13.3 0.0 0.073 12.3 0.0 1.5 1 0 0 1 1 1 0 StbA protein FAM91_C PF14648.6 EGO57169.1 - 0.23 10.3 0.4 0.45 9.3 0.4 1.4 1 0 0 1 1 1 0 FAM91 C-terminus Golgin_A5 PF09787.9 EGO57169.1 - 0.68 9.3 9.2 0.45 9.9 6.4 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 5 Paramyxo_C PF01692.18 EGO57171.1 - 0.009 15.4 0.2 0.011 15.2 0.2 1.2 1 0 0 1 1 1 1 Paramyxovirus non-structural protein C FUSC PF04632.12 EGO57172.1 - 0.011 14.3 4.3 0.014 14.0 4.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family FPP PF05911.11 EGO57172.1 - 0.017 13.4 6.8 0.02 13.1 6.8 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Acetyltransf_6 PF13480.7 EGO57172.1 - 0.048 13.8 3.2 0.065 13.4 3.2 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain V_ATPase_I PF01496.19 EGO57172.1 - 0.33 8.8 2.2 0.35 8.7 2.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IATP PF04568.12 EGO57172.1 - 8.4 6.9 14.1 0.25 11.8 5.7 2.1 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Arm-DNA-bind_5 PF17293.2 EGO57172.1 - 9.6 6.7 8.3 9.4 6.8 3.8 2.3 1 1 1 2 2 2 0 Arm DNA-binding domain RNase_HII PF01351.18 EGO57175.1 - 1.3e-48 165.5 0.1 2.4e-43 148.3 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease HII Mif2_N PF15624.6 EGO57176.1 - 7.3e-37 127.1 2.7 7.3e-37 127.1 2.7 3.6 2 1 1 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 EGO57176.1 - 7.8e-34 115.8 0.4 1.2e-33 115.1 0.4 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 EGO57176.1 - 1.2e-06 28.2 0.0 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EGO57176.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Cupin RHD3 PF05879.12 EGO57177.1 - 0 1134.7 0.0 0 1134.5 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EGO57177.1 - 1.7e-08 34.1 0.2 2.8e-08 33.4 0.2 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 EGO57177.1 - 4.6e-06 26.8 0.0 1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EGO57177.1 - 4.3e-05 23.6 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EGO57177.1 - 0.0019 18.5 0.1 0.008 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 EGO57177.1 - 0.077 12.3 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Septin Fructosamin_kin PF03881.14 EGO57178.1 - 1.5e-28 99.9 0.0 1.6e-28 99.8 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase RE_MjaI PF09568.10 EGO57178.1 - 0.0051 16.7 0.1 0.0066 16.3 0.1 1.1 1 0 0 1 1 1 1 MjaI restriction endonuclease EcKinase PF02958.20 EGO57178.1 - 0.0055 16.1 0.0 0.0068 15.8 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EGO57178.1 - 0.014 14.3 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) APH PF01636.23 EGO57178.1 - 0.052 13.5 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans_2 PF11951.8 EGO57179.1 - 3.1e-08 32.9 0.1 4.9e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO57179.1 - 1.7e-06 28.0 13.6 3e-06 27.2 13.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med18 PF09637.10 EGO57180.1 - 1.3e-55 188.9 0.0 1.5e-55 188.8 0.0 1.0 1 0 0 1 1 1 1 Med18 protein MccV PF17508.2 EGO57181.1 - 1.7 9.2 4.1 3.8 8.1 1.4 2.2 2 0 0 2 2 2 0 Microcin V bacteriocin FSA_C PF10479.9 EGO57181.1 - 8.4 4.4 6.4 10 4.1 6.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Amidohydro_1 PF01979.20 EGO57183.1 - 8e-59 199.7 0.0 9.4e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGO57183.1 - 1.1e-11 45.0 0.0 2.5e-09 37.2 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EGO57183.1 - 0.00012 21.6 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase TPR_12 PF13424.6 EGO57186.1 - 8.5e-08 32.4 0.2 0.014 15.7 0.0 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGO57186.1 - 2.7e-07 30.2 0.2 1 9.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGO57186.1 - 0.00047 20.7 2.2 2.2 9.3 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGO57186.1 - 0.0056 16.6 0.1 1.9 8.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGO57186.1 - 0.0061 16.3 0.0 1.5 8.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 EGO57186.1 - 0.0077 16.8 0.5 5.1 8.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 EGO57186.1 - 0.023 14.4 0.0 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_MalT PF17874.1 EGO57186.1 - 0.025 14.0 0.5 0.42 9.9 0.1 2.2 2 0 0 2 2 2 0 MalT-like TPR region TPR_2 PF07719.17 EGO57186.1 - 0.03 14.4 0.0 1.4 9.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Clr5 PF14420.6 EGO57186.1 - 0.037 14.3 0.1 0.13 12.6 0.1 1.9 1 0 0 1 1 1 0 Clr5 domain TPR_8 PF13181.6 EGO57186.1 - 0.068 13.4 0.0 2.7 8.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Clr5 PF14420.6 EGO57187.1 - 3.3e-09 36.8 0.0 5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Clr5 domain HET PF06985.11 EGO57190.1 - 5.8e-23 81.9 0.0 1.1e-22 81.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Hva1_TUDOR PF11160.8 EGO57191.1 - 2.8e-20 72.2 0.6 3.2e-20 72.0 0.6 1.0 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain PhoD PF09423.10 EGO57192.1 - 1.2e-78 264.6 0.9 1.6e-78 264.2 0.9 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EGO57192.1 - 8.9e-29 99.9 0.1 2.2e-28 98.6 0.1 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EGO57192.1 - 0.0012 19.3 0.3 0.003 18.1 0.3 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 EGO57192.1 - 0.0016 19.0 0.3 0.0028 18.2 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UPRTase PF14681.6 EGO57194.1 - 6.1e-29 101.0 0.4 1.7e-28 99.5 0.1 1.8 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase HAD PF12710.7 EGO57194.1 - 3.3e-23 83.1 0.1 7e-23 82.0 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.6 EGO57194.1 - 4.3e-20 72.5 0.0 9.8e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Hydrolase PF00702.26 EGO57194.1 - 7.3e-05 23.1 0.0 0.028 14.7 0.0 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase AAA_33 PF13671.6 EGO57194.1 - 0.00019 21.6 0.0 0.00043 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO57194.1 - 0.00046 20.8 0.0 0.0014 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGO57194.1 - 0.0018 18.5 0.3 0.0059 16.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGO57194.1 - 0.0022 18.4 0.4 0.026 14.9 0.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 EGO57194.1 - 0.0033 16.7 0.0 0.0059 15.9 0.0 1.4 1 1 0 1 1 1 1 KAP family P-loop domain AAA_5 PF07728.14 EGO57194.1 - 0.0094 16.0 0.1 0.15 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EGO57194.1 - 0.012 15.2 1.0 12 5.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 EGO57194.1 - 0.033 13.2 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 EGO57194.1 - 0.039 13.2 0.3 0.25 10.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Pribosyltran PF00156.27 EGO57194.1 - 0.041 13.4 0.1 0.19 11.2 0.1 2.0 1 1 0 1 1 1 0 Phosphoribosyl transferase domain ABC_tran PF00005.27 EGO57194.1 - 0.047 14.2 0.1 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Hydrolase_3 PF08282.12 EGO57194.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AAA_22 PF13401.6 EGO57194.1 - 0.089 13.1 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGO57194.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGO57194.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EGO57194.1 - 0.13 12.3 0.1 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase dNK PF01712.19 EGO57194.1 - 0.19 11.6 0.2 18 5.1 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_30 PF13604.6 EGO57194.1 - 0.25 11.1 1.9 0.52 10.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain Asp PF00026.23 EGO57195.1 - 4.4e-54 184.0 1.2 5.8e-54 183.6 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO57195.1 - 2e-13 50.9 5.3 2.8e-12 47.2 5.3 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EGO57195.1 - 0.0089 16.6 0.0 0.057 14.0 0.0 2.4 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGO57195.1 - 0.013 16.1 0.1 0.27 11.9 0.0 3.1 4 0 0 4 4 4 0 Aspartyl protease NUDIX PF00293.28 EGO57196.1 - 9.6e-12 45.1 0.2 1.5e-11 44.4 0.2 1.4 1 1 0 1 1 1 1 NUDIX domain DUF445 PF04286.12 EGO57198.1 - 0.075 12.8 0.9 0.17 11.7 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Shugoshin_N PF07558.11 EGO57198.1 - 0.2 11.6 1.6 0.38 10.7 1.6 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region PGAP1 PF07819.13 EGO57200.1 - 4e-05 23.4 0.1 0.0071 16.1 0.0 2.3 1 1 1 2 2 2 2 PGAP1-like protein Abhydrolase_6 PF12697.7 EGO57200.1 - 0.015 15.9 0.0 0.027 15.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 EGO57200.1 - 0.02 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 EGO57200.1 - 0.031 13.9 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 EGO57200.1 - 0.075 12.3 0.0 0.45 9.7 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF4407 PF14362.6 EGO57200.1 - 0.65 9.3 4.7 1.2 8.4 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.14 EGO57200.1 - 2.2 6.5 5.3 3.7 5.7 5.3 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF1524 PF07510.11 EGO57201.1 - 5.1e-09 36.1 0.0 6.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) SOG2 PF10428.9 EGO57202.1 - 4.9 6.2 18.5 5.5 6.1 18.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein O-FucT PF10250.9 EGO57204.1 - 5.7e-38 131.5 0.0 6.8e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase CAF1C_H4-bd PF12265.8 EGO57205.1 - 8.2e-14 51.6 0.0 2.8e-13 49.9 0.0 2.0 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGO57205.1 - 2.5e-13 50.3 9.3 1.3e-06 29.0 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO57205.1 - 6.1e-08 32.9 0.8 0.007 16.6 0.1 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain UL41A PF17591.2 EGO57205.1 - 0.047 13.8 0.1 0.19 11.8 0.1 2.0 1 0 0 1 1 1 0 Herpesvirus UL41A Nup160 PF11715.8 EGO57205.1 - 0.084 11.5 2.3 0.27 9.8 0.1 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 HATPase_c PF02518.26 EGO57206.1 - 4.6e-17 62.5 0.0 1.3e-16 61.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGO57206.1 - 1.3e-14 54.3 0.0 1.3e-11 44.7 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 EGO57206.1 - 7.9e-10 38.6 0.6 1.8e-09 37.5 0.6 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.6 EGO57206.1 - 0.0083 16.5 0.0 0.077 13.3 0.0 2.6 2 1 0 2 2 2 1 GAF domain YrbL-PhoP_reg PF10707.9 EGO57206.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Aldo_ket_red PF00248.21 EGO57207.1 - 7.2e-30 104.2 0.0 9.4e-19 67.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Dev_Cell_Death PF10539.9 EGO57207.1 - 0.2 11.5 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Development and cell death domain FAD_binding_4 PF01565.23 EGO57208.1 - 5.1e-23 81.3 3.6 1.6e-22 79.7 3.6 1.9 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGO57208.1 - 1.4e-14 53.9 0.3 2.9e-14 52.9 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like SQS_PSY PF00494.19 EGO57209.1 - 2.1e-76 256.9 0.0 2.6e-76 256.6 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.23 EGO57210.1 - 9.9e-70 235.0 0.0 1.4e-69 234.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EGO57210.1 - 1.1e-25 89.3 0.0 2e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EGO57210.1 - 2.4e-15 56.9 0.0 4.8e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO57210.1 - 3.5e-06 27.1 0.0 7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EGO57210.1 - 4.6e-05 23.2 8.7 9.1e-05 22.3 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO57210.1 - 0.00078 19.2 5.3 0.0018 18.1 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO57210.1 - 0.0021 18.3 8.9 0.0055 17.0 8.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGO57210.1 - 0.0054 16.6 8.4 0.013 15.4 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO57210.1 - 0.015 15.3 7.5 0.039 14.0 7.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger ERCC3_RAD25_C PF16203.5 EGO57210.1 - 0.017 14.4 0.1 0.054 12.7 0.2 1.7 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase DEAD_2 PF06733.15 EGO57210.1 - 0.037 13.7 0.0 0.086 12.5 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 UBA_4 PF14555.6 EGO57210.1 - 0.084 12.7 0.0 0.5 10.2 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain zf-RING_5 PF14634.6 EGO57210.1 - 0.19 11.7 7.7 0.51 10.3 7.7 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Defensin_beta PF00711.19 EGO57212.1 - 0.043 13.8 3.9 0.061 13.4 1.5 2.2 2 0 0 2 2 2 0 Beta defensin LDB19 PF13002.7 EGO57213.1 - 7.4e-35 120.4 0.2 1.2e-34 119.7 0.2 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 EGO57213.1 - 1.8e-06 28.1 0.4 4.3e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain SelP_N PF04592.14 EGO57213.1 - 0.16 11.4 18.1 0.33 10.3 18.1 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Androgen_recep PF02166.16 EGO57213.1 - 0.65 8.8 4.6 0.095 11.5 0.4 1.6 2 0 0 2 2 2 0 Androgen receptor SR-25 PF10500.9 EGO57213.1 - 1.1 8.8 10.8 2.2 7.8 10.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 EGO57213.1 - 3.7 6.0 5.3 6.6 5.2 5.3 1.4 1 0 0 1 1 1 0 Macoilin family GTP_EFTU PF00009.27 EGO57214.1 - 7.7e-18 64.7 0.0 1.4e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGO57214.1 - 1.3e-09 38.3 1.9 3.9e-09 36.8 0.9 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EGO57214.1 - 3.9e-05 23.9 0.0 8.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EGO57214.1 - 0.00069 19.7 0.1 0.0022 18.1 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO57214.1 - 0.0039 17.1 1.0 1.6 8.6 0.1 2.8 3 0 0 3 3 3 2 RsgA GTPase PduV-EutP PF10662.9 EGO57214.1 - 0.049 13.4 0.3 1.5 8.5 0.1 3.0 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 EGO57214.1 - 0.076 13.1 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Dynamin family Roc PF08477.13 EGO57214.1 - 0.18 12.0 0.1 1.9 8.7 0.0 2.4 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase LSM PF01423.22 EGO57215.1 - 2.9e-12 46.1 0.1 4.1e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain ATP13 PF12921.7 EGO57216.1 - 9.5e-19 67.4 0.0 1.1e-17 64.0 0.0 2.4 2 0 0 2 2 2 1 Mitochondrial ATPase expression PIG-L PF02585.17 EGO57217.1 - 1.8e-26 93.3 0.0 2.8e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase CbtA PF09490.10 EGO57218.1 - 8.8e-05 22.4 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) TMEM214 PF10151.9 EGO57218.1 - 0.0073 14.8 0.0 0.0084 14.6 0.0 1.2 1 0 0 1 1 1 1 TMEM214, C-terminal, caspase 4 activator Polysacc_deac_1 PF01522.21 EGO57219.1 - 1.1e-25 89.9 0.0 2.3e-25 88.9 0.0 1.5 1 1 1 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGO57219.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Abhydrolase_6 PF12697.7 EGO57220.1 - 7.8e-12 46.3 0.3 1.2e-11 45.6 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family MOSC PF03473.17 EGO57221.1 - 2e-27 95.8 0.0 3.5e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EGO57221.1 - 1.1e-09 38.2 0.0 8.2e-09 35.4 0.0 2.2 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF2673 PF10880.8 EGO57222.1 - 8.6 6.6 6.3 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) PAP1 PF08601.10 EGO57224.1 - 2.4 7.8 15.4 0.25 11.0 10.4 1.8 2 0 0 2 2 2 0 Transcription factor PAP1 AAA PF00004.29 EGO57225.1 - 1.9e-07 31.6 0.0 4.2e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGO57225.1 - 0.00046 20.2 0.1 0.0014 18.6 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 EGO57225.1 - 0.00071 20.0 0.1 0.0032 17.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGO57225.1 - 0.0052 17.1 0.1 0.022 15.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EGO57225.1 - 0.022 14.7 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EGO57225.1 - 0.076 13.1 0.0 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain HABP4_PAI-RBP1 PF04774.15 EGO57226.1 - 9.3 7.1 9.9 18 6.2 0.3 3.1 3 0 0 3 3 3 0 Hyaluronan / mRNA binding family CssAB PF16831.5 EGO57227.1 - 0.0042 17.5 0.5 0.0042 17.5 0.5 2.4 2 1 0 3 3 3 1 CS6 fimbrial subunits A and B, Coli surface antigen 6 FA_desaturase PF00487.24 EGO57229.1 - 8.2e-23 81.5 31.0 8.2e-23 81.5 31.0 1.7 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 EGO57229.1 - 9.1e-07 29.1 0.0 1.9e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Fungal_trans PF04082.18 EGO57230.1 - 6.1e-18 64.8 0.1 9.2e-18 64.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EGO57230.1 - 9.1e-09 35.3 12.4 0.00049 20.4 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO57230.1 - 5.5e-07 29.7 11.5 9e-07 29.1 5.8 3.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO57230.1 - 0.00045 20.8 11.9 0.12 13.3 1.5 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGO57230.1 - 0.34 11.2 2.5 0.78 10.1 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGO57230.1 - 1.6 9.2 4.3 0.57 10.6 0.9 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2722 PF10846.8 EGO57234.1 - 0.0068 15.4 3.1 0.0075 15.3 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) IER PF05760.12 EGO57234.1 - 0.86 9.8 8.9 1 9.6 8.9 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) SUIM_assoc PF16619.5 EGO57234.1 - 7.9 6.6 17.2 4.1 7.5 14.5 1.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PKHD_C PF18331.1 EGO57238.1 - 0.0051 16.8 0.1 1.2 9.3 0.1 2.5 2 0 0 2 2 2 2 PKHD-type hydroxylase C-terminal domain MFS_1 PF07690.16 EGO57239.1 - 1.2e-30 106.7 39.8 4.2e-30 104.9 27.2 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO57239.1 - 6.9e-14 51.6 2.9 6.9e-14 51.6 2.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EGO57239.1 - 7.6e-09 34.5 2.0 7.6e-09 34.5 2.0 2.0 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) ArAE_2_N PF10337.9 EGO57240.1 - 6.1e-40 137.7 7.0 8.9e-33 114.0 0.4 4.2 2 2 1 4 4 4 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EGO57240.1 - 2.9e-23 82.4 15.0 2.9e-23 82.4 15.0 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 EGO57240.1 - 1.6e-05 24.9 0.1 0.0016 18.3 0.0 2.7 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 EGO57240.1 - 0.029 13.2 3.7 0.066 12.0 3.7 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter AAA_12 PF13087.6 EGO57242.1 - 2.4e-28 99.1 0.0 5.7e-28 97.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGO57242.1 - 1.8e-22 80.4 1.7 1.4e-12 47.9 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 EGO57242.1 - 1.7e-07 31.1 0.0 1.3e-06 28.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGO57242.1 - 5.1e-07 30.1 0.0 1.2e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EGO57242.1 - 0.00016 21.3 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 EGO57242.1 - 0.00026 21.0 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EGO57242.1 - 0.00093 18.5 0.0 0.36 10.0 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 EGO57242.1 - 0.0026 17.7 0.0 0.017 15.0 0.0 2.2 1 1 0 1 1 1 1 Helicase AAA_22 PF13401.6 EGO57242.1 - 0.014 15.6 0.0 0.055 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EGO57242.1 - 0.038 13.7 0.0 25 4.5 0.0 4.1 4 1 0 4 4 4 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 EGO57242.1 - 0.076 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.29 EGO57242.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EGO57242.1 - 0.15 11.5 0.0 0.79 9.1 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein HPP PF04982.13 EGO57243.1 - 2.6e-41 140.6 7.1 2.6e-41 140.6 7.1 1.5 2 0 0 2 2 2 1 HPP family eRF1_1 PF03463.15 EGO57244.1 - 2.7e-41 140.6 0.0 5e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 EGO57244.1 - 4.6e-20 72.3 0.0 8.1e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EGO57244.1 - 5.5e-18 65.5 0.0 1.2e-17 64.4 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 WD40 PF00400.32 EGO57245.1 - 7.5e-27 93.1 8.0 2.3e-05 25.1 0.1 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO57245.1 - 0.00014 22.1 0.1 3 8.2 0.0 4.4 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO57245.1 - 0.042 12.5 0.5 8.7 4.9 0.0 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGO57245.1 - 0.12 11.4 0.1 3.3 6.6 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FAD_binding_4 PF01565.23 EGO57246.1 - 7.6e-23 80.8 1.9 7.6e-23 80.8 1.9 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EGO57246.1 - 0.0032 17.5 0.1 0.0075 16.4 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 EGO57248.1 - 2.3e-27 95.4 0.5 3.5e-27 94.9 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGO57248.1 - 0.0019 18.2 0.6 0.0056 16.7 0.1 2.0 2 0 0 2 2 2 1 Berberine and berberine like cwf21 PF08312.12 EGO57249.1 - 0.15 12.3 3.7 0.52 10.5 0.5 2.2 2 0 0 2 2 2 0 cwf21 domain FYDLN_acid PF09538.10 EGO57249.1 - 5.5 7.7 7.8 0.71 10.6 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Pox_I5 PF04713.12 EGO57250.1 - 0.12 12.5 3.0 1.7 8.8 3.0 2.3 1 1 0 1 1 1 0 Poxvirus protein I5 NmrA PF05368.13 EGO57252.1 - 2.2e-72 243.4 0.0 2.7e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO57252.1 - 3.1e-19 69.6 0.0 4.9e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGO57252.1 - 1e-07 31.3 0.1 1.4e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGO57252.1 - 9.8e-06 25.2 0.1 1.6e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EGO57252.1 - 0.036 14.3 0.1 0.058 13.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EGO57252.1 - 0.044 14.1 0.2 0.074 13.3 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 EGO57252.1 - 0.074 12.6 0.5 0.11 12.0 0.5 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_43 PF04616.14 EGO57253.1 - 5e-59 200.0 3.0 6e-59 199.7 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 AbfB PF05270.13 EGO57253.1 - 2.4e-16 60.0 0.1 8.7e-16 58.2 0.1 2.0 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain Kelch_5 PF13854.6 EGO57254.1 - 1.4e-12 47.3 14.1 9.2e-09 35.1 0.6 5.4 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 EGO57254.1 - 4.2e-08 33.1 6.1 0.014 15.4 0.0 5.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EGO57254.1 - 0.00025 21.2 12.1 0.38 11.1 0.6 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EGO57254.1 - 0.00058 19.7 8.3 0.12 12.4 0.0 5.6 5 0 0 5 5 5 1 Kelch motif Kelch_6 PF13964.6 EGO57254.1 - 0.0046 17.2 15.9 0.35 11.2 0.0 5.5 6 0 0 6 6 6 2 Kelch motif VSP PF03302.13 EGO57254.1 - 0.022 13.7 0.3 0.032 13.1 0.3 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.10 EGO57254.1 - 0.053 12.9 0.5 0.11 12.0 0.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_1 PF01344.25 EGO57254.1 - 0.056 13.0 12.0 0.53 9.9 0.0 4.5 6 0 0 6 6 6 0 Kelch motif MFS_1 PF07690.16 EGO57255.1 - 8.8e-35 120.3 48.4 4.3e-34 118.0 48.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3445 PF11927.8 EGO57256.1 - 3.7e-66 223.0 0.1 5.2e-66 222.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF1163 PF06651.11 EGO57256.1 - 0.069 13.2 0.4 2.7 8.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1163) Glyco_hydro_17 PF00332.18 EGO57258.1 - 2e-08 34.2 0.7 2.9e-08 33.7 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 CHORD PF04968.12 EGO57261.1 - 0.019 15.7 0.3 0.019 15.7 0.3 2.4 1 1 1 2 2 2 0 CHORD CCDC71L PF15374.6 EGO57261.1 - 0.036 13.4 6.7 0.045 13.0 6.7 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L CDC27 PF09507.10 EGO57261.1 - 2.6 7.3 17.1 3.3 7.0 17.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ndc1_Nup PF09531.10 EGO57261.1 - 3.9 6.0 5.1 4.2 5.9 5.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 EGO57261.1 - 8.7 6.3 6.1 11 6.0 6.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Oxidored-like PF09791.9 EGO57262.1 - 0.15 11.7 2.2 0.5 10.1 2.2 1.8 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal zf-RRPl_C4 PF17026.5 EGO57262.1 - 0.22 11.7 0.1 0.35 11.0 0.1 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type DMAP1_like PF17024.5 EGO57263.1 - 0.036 14.2 0.2 0.053 13.6 0.2 1.2 1 0 0 1 1 1 0 Putative DMAP1-like DUF4710 PF15828.5 EGO57263.1 - 0.3 11.2 4.8 0.55 10.4 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) BUD22 PF09073.10 EGO57263.1 - 7.1 5.9 14.9 12 5.1 14.9 1.3 1 1 0 1 1 1 0 BUD22 Aminotran_5 PF00266.19 EGO57264.1 - 1.6e-08 33.9 0.0 6.7e-08 31.9 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGO57264.1 - 0.00096 17.8 0.0 0.0014 17.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGO57264.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IDO PF01231.18 EGO57265.1 - 5e-29 101.4 0.0 6.9e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase IDO PF01231.18 EGO57266.1 - 1.1e-74 251.9 0.0 1.2e-74 251.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase AAA PF00004.29 EGO57267.1 - 8.1e-10 39.2 4.1 2e-07 31.5 4.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGO57267.1 - 0.072 13.5 0.7 0.45 10.9 0.2 2.6 2 1 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 EGO57267.1 - 0.27 10.5 2.3 7.2 5.9 0.6 2.5 1 1 1 2 2 2 0 KaiC DUF2207 PF09972.9 EGO57268.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NeuB PF03102.14 EGO57268.1 - 0.17 11.3 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 NeuB family Tri3 PF07428.11 EGO57269.1 - 2.5e-09 36.5 0.0 4.9e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 p450 PF00067.22 EGO57270.1 - 3.6e-44 151.3 0.0 5e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EGO57271.1 - 1.1e-18 67.6 0.0 1.2e-09 37.9 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57271.1 - 7.8e-07 28.6 0.0 0.037 13.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGO57271.1 - 0.00017 21.0 0.0 0.27 10.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EGO57271.1 - 0.016 15.1 0.1 0.038 13.9 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGO57271.1 - 0.26 10.6 0.3 0.47 9.8 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_Packaging PF11053.8 EGO57272.1 - 0.16 11.8 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 Terminase DNA packaging enzyme HeH PF12949.7 EGO57272.1 - 0.19 11.4 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 HeH/LEM domain Pkinase PF00069.25 EGO57273.1 - 0.0003 20.2 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HET PF06985.11 EGO57276.1 - 2.1e-12 47.6 0.1 8.5e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 EGO57277.1 - 1.8e-16 60.3 0.0 6.8e-05 22.3 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57277.1 - 0.00087 18.6 0.0 0.72 9.1 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 EGO57277.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RXT2_N PF08595.11 EGO57277.1 - 0.01 15.9 0.6 0.016 15.2 0.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF3958 PF13125.6 EGO57277.1 - 0.082 13.1 1.8 0.2 11.8 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) APH PF01636.23 EGO57277.1 - 0.16 11.8 1.9 0.34 10.8 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family WYL_2 PF10902.8 EGO57278.1 - 0.055 13.9 0.1 0.097 13.1 0.1 1.4 1 0 0 1 1 1 0 WYL_2, Sm-like SH3 beta-barrel fold BBIP10 PF14777.6 EGO57279.1 - 0.12 12.0 0.0 3.7 7.2 0.0 2.6 3 0 0 3 3 3 0 Cilia BBSome complex subunit 10 Pkinase PF00069.25 EGO57282.1 - 0.00012 21.5 0.0 0.0038 16.6 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain GARP PF16731.5 EGO57284.1 - 0.099 12.3 0.3 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF4050 PF13259.6 EGO57284.1 - 0.68 10.2 9.2 0.11 12.8 5.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) SMN PF06003.12 EGO57285.1 - 4 6.6 8.4 0.37 10.0 3.8 1.6 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) BAF PF02961.14 EGO57287.1 - 0.077 13.4 0.3 11 6.6 0.1 2.5 2 0 0 2 2 2 0 Barrier to autointegration factor PI3K_1B_p101 PF10486.9 EGO57287.1 - 0.54 8.0 7.8 0.7 7.6 7.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GPI-anchored PF10342.9 EGO57288.1 - 4.6e-14 53.0 0.3 4.6e-14 53.0 0.3 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Plasmodium_Vir PF05795.11 EGO57288.1 - 1.2 8.4 3.2 1.5 8.2 3.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.9 EGO57288.1 - 2.6 6.5 5.2 2.9 6.3 5.2 1.0 1 0 0 1 1 1 0 Macoilin family HATPase_c_2 PF13581.6 EGO57290.1 - 0.0084 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Ank_4 PF13637.6 EGO57292.1 - 1.2e-10 41.7 0.7 1.9e-05 25.1 0.0 4.0 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO57292.1 - 8.5e-09 35.9 0.3 0.0002 21.9 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGO57292.1 - 2.1e-08 34.2 0.7 0.00095 19.4 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGO57292.1 - 3.3e-07 30.5 0.5 0.015 15.7 0.0 4.4 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EGO57292.1 - 1.3e-05 25.2 0.2 0.031 14.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat DUF4212 PF13937.6 EGO57293.1 - 1.8 9.0 6.8 0.22 12.0 2.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) Rubella_Capsid PF05750.11 EGO57294.1 - 1.4 8.5 7.7 0.82 9.2 6.0 1.5 1 1 0 1 1 1 0 Rubella capsid protein PPP4R2 PF09184.11 EGO57295.1 - 0.0013 18.4 9.7 0.0013 18.4 9.7 2.1 2 0 0 2 2 2 1 PPP4R2 Mpp10 PF04006.12 EGO57295.1 - 0.0019 16.8 32.1 0.0023 16.4 32.1 1.1 1 0 0 1 1 1 1 Mpp10 protein Nop14 PF04147.12 EGO57295.1 - 0.011 14.0 29.1 0.015 13.6 29.1 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EGO57295.1 - 0.028 13.8 24.3 0.039 13.3 24.3 1.3 1 0 0 1 1 1 0 BUD22 Nop53 PF07767.11 EGO57295.1 - 0.26 10.6 36.5 0.37 10.1 36.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CLN3 PF02487.17 EGO57295.1 - 0.54 9.2 1.2 0.71 8.9 1.2 1.2 1 0 0 1 1 1 0 CLN3 protein HA2 PF04408.23 EGO57295.1 - 0.63 10.3 0.1 0.63 10.3 0.1 2.3 2 0 0 2 2 2 0 Helicase associated domain (HA2) FRQ PF09421.10 EGO57295.1 - 2.2 6.2 11.3 3.1 5.7 11.3 1.1 1 0 0 1 1 1 0 Frequency clock protein Presenilin PF01080.17 EGO57295.1 - 2.7 6.7 13.5 3.5 6.3 13.5 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 EGO57295.1 - 3.2 6.7 8.6 4.1 6.3 8.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF1980 PF09323.10 EGO57295.1 - 3.9 7.3 4.2 10 6.0 4.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) Mcm10 PF09332.11 EGO57297.1 - 0.18 11.2 0.1 0.26 10.7 0.1 1.2 1 0 0 1 1 1 0 Mcm10 replication factor SDA1 PF05285.12 EGO57300.1 - 0.1 12.0 16.5 0.14 11.5 16.5 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EGO57300.1 - 0.22 9.7 19.7 0.24 9.6 19.7 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EGO57300.1 - 0.27 10.5 15.7 0.32 10.3 15.7 1.1 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 EGO57300.1 - 0.4 10.2 16.6 0.55 9.8 16.6 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 EGO57300.1 - 0.55 9.5 19.2 0.84 8.9 19.2 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EGO57300.1 - 1.4 7.0 20.4 2.3 6.2 20.4 1.4 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 EGO57300.1 - 2 6.4 10.1 2.3 6.2 10.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dicty_REP PF05086.12 EGO57300.1 - 2.8 5.8 6.5 3.9 5.3 6.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cwf_Cwc_15 PF04889.12 EGO57300.1 - 5.2 6.7 23.0 6.6 6.4 22.0 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 EGO57300.1 - 5.3 5.7 10.5 7.3 5.2 10.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein zf-CCHC_6 PF15288.6 EGO57301.1 - 0.15 11.9 0.5 0.15 11.9 0.5 2.5 2 0 0 2 2 2 0 Zinc knuckle LST1 PF05083.13 EGO57302.1 - 8.5 6.7 6.8 4.4 7.7 0.8 3.1 3 1 0 3 3 3 0 LST-1 protein Glyco_transf_15 PF01793.16 EGO57303.1 - 1.2e-95 320.5 8.4 8.5e-95 317.7 8.4 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Myb_DNA-binding PF00249.31 EGO57304.1 - 0.00033 20.8 0.2 0.0023 18.1 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO57304.1 - 0.0037 17.5 0.2 0.012 15.9 0.2 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain ILVD_EDD PF00920.21 EGO57305.1 - 1.7e-204 680.3 0.7 2e-204 680.0 0.7 1.0 1 0 0 1 1 1 1 Dehydratase family NUFIP1 PF10453.9 EGO57305.1 - 0.21 11.5 0.7 0.53 10.2 0.7 1.6 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Myb_DNA-binding PF00249.31 EGO57308.1 - 1e-15 57.7 1.4 2.1e-09 37.4 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO57308.1 - 1.1e-08 35.1 0.3 0.0002 21.6 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Glyco_hydro_16 PF00722.21 EGO57310.1 - 8e-47 159.0 4.7 1.2e-46 158.3 4.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 EGO57310.1 - 1.5 9.3 19.0 0.057 13.9 12.4 2.0 2 0 0 2 2 2 0 Chitin recognition protein Clr5 PF14420.6 EGO57311.1 - 6.6e-18 64.7 1.0 1.2e-17 63.8 1.0 1.5 1 0 0 1 1 1 1 Clr5 domain DUF4604 PF15377.6 EGO57312.1 - 1.4e-28 100.5 23.6 7.7e-28 98.1 23.6 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) BUD22 PF09073.10 EGO57312.1 - 0.0091 15.4 17.0 0.011 15.2 17.0 1.1 1 0 0 1 1 1 1 BUD22 COX5B PF01215.19 EGO57313.1 - 2.2e-58 195.5 0.0 2.8e-58 195.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.19 EGO57313.1 - 0.075 12.8 0.5 12 5.8 0.2 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger CTNNB1_binding PF08347.11 EGO57313.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 N-terminal CTNNB1 binding OHCU_decarbox PF09349.10 EGO57317.1 - 8e-50 169.3 0.0 9.8e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase DUF4404 PF14357.6 EGO57317.1 - 0.0044 17.6 0.8 0.026 15.2 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4404) Dynamin_N PF00350.23 EGO57318.1 - 7.9e-36 123.6 0.1 7.9e-36 123.6 0.1 2.6 3 0 0 3 3 3 1 Dynamin family Dynamin_M PF01031.20 EGO57318.1 - 9.7e-29 100.5 1.2 3.2e-23 82.4 0.0 2.7 3 0 0 3 3 3 2 Dynamin central region GED PF02212.18 EGO57318.1 - 0.00018 21.6 0.6 0.00092 19.3 0.1 2.6 2 1 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGO57318.1 - 0.011 15.9 0.3 0.096 12.8 0.3 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO57318.1 - 0.016 14.7 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Sigma70_ner PF04546.13 EGO57318.1 - 8.7 6.2 12.8 1.1 9.1 2.0 3.6 3 1 1 4 4 4 0 Sigma-70, non-essential region DUF2235 PF09994.9 EGO57319.1 - 2.3e-80 270.0 0.0 3.2e-80 269.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Plasmid_RAQPRD PF09686.10 EGO57320.1 - 7.3 6.9 9.1 24 5.2 0.2 3.5 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) PhzC-PhzF PF02567.16 EGO57321.1 - 6.5e-37 127.5 0.2 1.8e-36 126.1 0.2 1.7 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein SpaA PF17802.1 EGO57321.1 - 0.12 12.7 0.1 0.27 11.6 0.1 1.6 1 0 0 1 1 1 0 Prealbumin-like fold domain Prp19 PF08606.11 EGO57322.1 - 3.6e-31 107.0 3.0 7.7e-31 105.9 3.0 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 EGO57322.1 - 2.9e-12 46.7 0.0 5.3e-05 23.4 0.0 4.6 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO57322.1 - 9.3e-10 39.0 1.6 0.062 14.2 0.0 5.0 6 0 0 6 6 4 2 WD domain, G-beta repeat eIF2A PF08662.11 EGO57322.1 - 2e-05 24.5 0.1 0.012 15.5 0.1 3.2 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 EGO57322.1 - 3e-05 23.3 0.0 0.032 13.3 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region Cytochrom_D1 PF02239.16 EGO57322.1 - 0.0023 16.5 0.0 0.0084 14.7 0.0 1.9 2 0 0 2 2 2 1 Cytochrome D1 heme domain zf-Nse PF11789.8 EGO57322.1 - 0.005 16.6 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit V_ATPase_I_N PF18670.1 EGO57322.1 - 0.0079 16.6 1.7 0.034 14.5 1.4 2.1 2 0 0 2 2 2 1 V-type ATPase subunit I, N-terminal domain Fim-adh_lectin PF09222.10 EGO57322.1 - 0.026 14.0 0.3 0.045 13.3 0.3 1.3 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain WD40_like PF17005.5 EGO57322.1 - 0.057 12.7 0.0 7.8 5.7 0.0 2.3 1 1 1 3 3 3 0 WD40-like domain Frtz PF11768.8 EGO57322.1 - 0.15 10.4 0.0 0.23 9.8 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz zf-RING_5 PF14634.6 EGO57323.1 - 0.0059 16.5 3.9 0.016 15.2 3.9 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGO57323.1 - 0.019 15.0 4.2 0.042 13.9 4.2 1.6 1 1 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EGO57323.1 - 0.06 13.2 2.9 0.17 11.8 1.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGO57323.1 - 0.17 11.8 5.3 0.46 10.4 5.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO57323.1 - 0.7 9.8 4.6 0.37 10.7 1.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO57323.1 - 1.5 9.2 5.0 0.94 9.9 2.2 1.9 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.6 EGO57323.1 - 1.8 8.8 4.6 2 8.6 2.0 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Syntaxin_2 PF14523.6 EGO57324.1 - 0.064 13.6 0.1 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Osmo_MPGsynth PF09488.10 EGO57328.1 - 3.7e-138 460.4 0.0 4.9e-138 460.1 0.0 1.1 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) DUF4558 PF15104.6 EGO57330.1 - 0.13 12.3 0.5 0.2 11.7 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) GST_N PF02798.20 EGO57333.1 - 3.1e-10 40.3 0.0 6.7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO57333.1 - 6.4e-08 32.9 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO57333.1 - 2.6e-07 30.8 0.1 8.6e-07 29.2 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO57333.1 - 5.5e-07 29.7 0.0 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO57333.1 - 1.2e-06 28.7 0.0 2.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO57333.1 - 1.5e-05 24.9 0.0 5.2e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGO57333.1 - 0.028 15.0 0.0 0.048 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FAD_binding_3 PF01494.19 EGO57335.1 - 2.4e-73 247.4 0.0 3.2e-73 247.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGO57335.1 - 1.7e-43 148.5 0.1 3.1e-43 147.7 0.1 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 EGO57335.1 - 0.0014 17.8 0.0 0.0078 15.3 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EGO57335.1 - 0.0056 16.0 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EGO57335.1 - 0.009 15.4 0.2 0.02 14.3 0.1 1.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 EGO57335.1 - 0.01 15.5 0.6 0.02 14.5 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO57335.1 - 0.031 13.5 0.1 0.29 10.3 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EGO57335.1 - 0.048 12.7 0.0 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_8 PF13450.6 EGO57335.1 - 0.061 13.6 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGO57335.1 - 0.092 13.3 0.0 1 9.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S9 PF00326.21 EGO57336.1 - 2.4e-07 30.5 0.1 0.0061 16.1 0.2 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGO57336.1 - 5.4e-07 29.5 0.1 1.3e-06 28.2 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO57336.1 - 1.5e-06 27.7 0.0 0.00085 18.7 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 EGO57336.1 - 1.1e-05 25.1 0.0 1.5e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EGO57336.1 - 0.00011 23.0 3.3 0.00031 21.4 3.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EGO57336.1 - 0.00064 19.5 0.0 0.00094 19.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.11 EGO57336.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.5 1 1 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.16 EGO57336.1 - 0.021 14.6 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF915 PF06028.11 EGO57336.1 - 0.039 13.3 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_7 PF12715.7 EGO57336.1 - 0.053 12.8 0.0 5.5 6.1 0.0 2.1 2 0 0 2 2 2 0 Abhydrolase family Abhydrolase_4 PF08386.10 EGO57336.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein FMO-like PF00743.19 EGO57337.1 - 2.7e-28 98.7 0.2 2.9e-21 75.5 0.1 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGO57337.1 - 2.4e-14 53.3 0.2 2.4e-12 46.7 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO57337.1 - 9.4e-10 38.2 0.0 6.1e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO57337.1 - 8.7e-09 35.0 0.0 4.9e-07 29.2 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGO57337.1 - 8.2e-06 25.9 0.0 6.9e-05 22.9 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EGO57337.1 - 0.00031 20.4 0.1 0.89 9.1 0.1 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO57337.1 - 0.00034 20.8 0.0 0.00073 19.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DnaJ PF00226.31 EGO57338.1 - 3.4e-21 75.1 0.8 3.4e-21 75.1 0.8 2.3 2 1 0 2 2 2 1 DnaJ domain Fib_alpha PF08702.10 EGO57338.1 - 0.021 15.0 7.6 0.03 14.5 0.5 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CC2-LZ PF16516.5 EGO57338.1 - 0.024 15.0 1.1 0.024 15.0 1.1 2.3 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF1912 PF08930.10 EGO57338.1 - 0.056 13.6 1.4 0.33 11.1 0.1 2.5 2 1 0 3 3 3 0 Domain of unknown function (DUF1912) CCDC53 PF10152.9 EGO57338.1 - 0.072 13.5 0.6 0.16 12.4 0.5 1.6 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex LegC3_N PF18654.1 EGO57338.1 - 0.12 11.6 10.0 0.16 11.2 10.0 1.1 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain MADF_DNA_bdg PF10545.9 EGO57338.1 - 0.41 11.0 3.6 2.6 8.4 0.2 2.5 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Jnk-SapK_ap_N PF09744.9 EGO57338.1 - 5.4 7.2 14.3 5.2 7.3 5.9 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TolA_bind_tri PF16331.5 EGO57339.1 - 0.0049 16.9 6.2 0.0049 16.9 6.2 3.0 2 1 1 3 3 3 1 TolA binding protein trimerisation Csm1_N PF18504.1 EGO57339.1 - 0.035 14.5 3.2 0.035 14.5 3.2 4.2 2 2 2 4 4 4 0 Csm1 N-terminal domain CCDC92 PF14916.6 EGO57339.1 - 0.14 12.0 4.5 3.3 7.6 0.0 3.0 2 0 0 2 2 2 0 Coiled-coil domain of unknown function DUF5388 PF17363.2 EGO57339.1 - 0.82 9.9 4.1 4.6 7.5 0.1 3.0 1 1 2 3 3 3 0 Family of unknown function (DUF5388) SlyX PF04102.12 EGO57339.1 - 6.9 7.4 15.4 2.4 8.9 8.1 3.5 1 1 1 2 2 2 0 SlyX Post_transc_reg PF13797.6 EGO57341.1 - 0.067 13.1 0.0 5.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Post-transcriptional regulator Ribosomal_L27A PF00828.19 EGO57342.1 - 1e-33 116.7 1.0 1.9e-33 115.8 1.0 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A PX PF00787.24 EGO57343.1 - 6e-18 64.9 0.1 1.2e-17 63.9 0.1 1.5 1 0 0 1 1 1 1 PX domain Cullin_binding PF03556.15 EGO57344.1 - 2.7e-33 115.0 2.0 3.7e-33 114.5 2.0 1.2 1 0 0 1 1 1 1 Cullin binding Ribosomal_S6 PF01250.17 EGO57345.1 - 6.7e-25 87.2 0.0 7.8e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 DUF3716 PF12511.8 EGO57346.1 - 7.9e-08 32.2 8.5 1.5e-07 31.3 8.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Chs7 PF12271.8 EGO57347.1 - 2e-123 411.4 15.3 2.2e-123 411.2 15.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone MpPF26 PF07666.11 EGO57347.1 - 0.97 9.5 9.5 1.9 8.6 0.6 2.6 2 0 0 2 2 2 0 M penetrans paralogue family 26 Arrestin_C PF02752.22 EGO57348.1 - 2.4e-15 57.2 0.0 4.2e-14 53.1 0.0 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGO57348.1 - 1.5e-06 28.4 0.1 0.075 13.1 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Pkinase PF00069.25 EGO57350.1 - 4e-05 23.1 0.0 0.0005 19.5 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57350.1 - 0.0037 16.6 0.0 0.16 11.2 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase Spc7 PF08317.11 EGO57351.1 - 6.1e-06 25.3 84.0 0.027 13.3 10.4 5.4 1 1 3 5 5 5 4 Spc7 kinetochore protein NPV_P10 PF05531.12 EGO57351.1 - 0.00065 20.1 13.1 0.0019 18.6 1.4 7.4 3 2 6 9 9 9 2 Nucleopolyhedrovirus P10 protein MAD PF05557.13 EGO57351.1 - 0.00067 18.2 23.4 0.00067 18.2 23.4 4.3 1 1 3 4 4 3 1 Mitotic checkpoint protein GAS PF13851.6 EGO57351.1 - 0.0031 16.9 83.2 0.14 11.5 5.4 6.4 2 1 3 6 6 6 5 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 EGO57351.1 - 0.0042 16.6 32.0 0.0042 16.6 32.0 4.7 1 1 3 5 5 4 2 Hyaluronan mediated motility receptor N-terminal TRAF_BIRC3_bd PF16673.5 EGO57351.1 - 0.0089 15.8 1.8 0.0089 15.8 1.8 5.8 6 0 0 6 6 5 1 TNF receptor-associated factor BIRC3 binding domain DUF1664 PF07889.12 EGO57351.1 - 0.0091 16.0 4.1 0.0091 16.0 4.1 7.0 2 2 3 7 7 7 3 Protein of unknown function (DUF1664) APG6_N PF17675.1 EGO57351.1 - 0.013 16.1 97.1 0.21 12.1 1.2 7.7 2 2 3 6 6 5 0 Apg6 coiled-coil region HOOK PF05622.12 EGO57351.1 - 0.03 12.5 85.7 0.0024 16.1 44.2 3.1 1 1 2 3 3 3 0 HOOK protein TMF_DNA_bd PF12329.8 EGO57351.1 - 0.13 12.2 85.8 0.37 10.8 0.9 9.7 5 3 6 11 11 11 0 TATA element modulatory factor 1 DNA binding DUF812 PF05667.11 EGO57351.1 - 0.35 9.7 76.2 0.011 14.7 21.1 3.4 1 1 1 2 2 1 0 Protein of unknown function (DUF812) Shugoshin_N PF07558.11 EGO57351.1 - 0.57 10.1 0.0 0.57 10.1 0.0 7.0 8 1 1 9 9 9 0 Shugoshin N-terminal coiled-coil region ATG16 PF08614.11 EGO57351.1 - 0.81 9.9 104.3 0.034 14.4 9.5 7.1 1 1 5 6 6 6 0 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.11 EGO57351.1 - 1.6 9.3 49.7 0.084 13.4 1.5 7.2 4 3 3 7 7 6 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 EGO57351.1 - 1.7 9.1 0.0 0.98 9.9 1.0 10.2 9 2 1 10 10 10 0 Flagella accessory protein C (FlaC) Pox_A_type_inc PF04508.12 EGO57351.1 - 2.1 8.4 16.2 21 5.2 0.1 6.8 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat TSC22 PF01166.18 EGO57351.1 - 3.1 8.2 36.1 0.38 11.1 2.6 8.3 6 3 1 7 7 7 0 TSC-22/dip/bun family CALCOCO1 PF07888.11 EGO57351.1 - 5.4 5.8 93.9 0.049 12.5 12.2 4.1 1 1 3 4 4 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like Cyclin PF08613.11 EGO57354.1 - 5.9e-13 49.5 0.0 1.3e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGO57354.1 - 0.00028 20.6 0.1 0.00028 20.6 0.1 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Metaviral_G PF09595.10 EGO57355.1 - 0.056 13.5 2.2 0.11 12.6 1.6 1.7 1 1 0 1 1 1 0 Metaviral_G glycoprotein PrmA PF06325.13 EGO57359.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SnoaL_4 PF13577.6 EGO57360.1 - 2e-07 31.2 0.2 2.9e-07 30.7 0.2 1.3 1 0 0 1 1 1 1 SnoaL-like domain Thioredoxin PF00085.20 EGO57361.1 - 6e-25 87.2 0.2 8.3e-25 86.8 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EGO57361.1 - 1.4e-05 24.6 0.2 1.8e-05 24.2 0.2 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EGO57361.1 - 1.9e-05 24.9 0.1 9.9e-05 22.6 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGO57361.1 - 0.00011 22.6 0.4 0.0013 19.2 0.4 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EGO57361.1 - 0.0005 20.0 0.0 0.00075 19.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EGO57361.1 - 0.0015 18.3 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EGO57361.1 - 0.017 15.3 0.2 0.037 14.2 0.2 1.6 1 0 0 1 1 1 0 Thioredoxin-like DIM1 PF02966.16 EGO57361.1 - 0.024 14.4 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 HyaE PF07449.11 EGO57361.1 - 0.026 14.5 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Fungal_trans_2 PF11951.8 EGO57365.1 - 1.1e-31 110.0 0.5 2.2e-31 109.0 0.5 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO57365.1 - 6.9e-08 32.5 5.0 1.2e-07 31.7 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EGO57366.1 - 6.2e-40 137.2 56.5 2.5e-39 135.2 56.0 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily COX2_TM PF02790.15 EGO57366.1 - 0.026 14.7 0.6 0.19 11.9 1.0 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF1418 PF07214.12 EGO57366.1 - 1.1 9.2 4.3 0.93 9.4 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1418) UCR_UQCRX_QCR9 PF05365.12 EGO57372.1 - 0.07 13.1 2.3 0.079 12.9 0.8 1.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like ComR_TPR PF18710.1 EGO57372.1 - 0.12 11.9 0.2 2.7 7.5 0.2 2.0 1 1 1 2 2 2 0 ComR tetratricopeptide RVT_1 PF00078.27 EGO57374.1 - 0.002 17.7 0.1 0.0029 17.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 EGO57377.1 - 5.1e-08 32.7 1.0 5.5e-08 32.6 1.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF226 PF02890.14 EGO57377.1 - 0.0065 16.5 3.6 0.0079 16.2 3.6 1.1 1 0 0 1 1 1 1 Borrelia family of unknown function DUF226 Gin PF10764.9 EGO57377.1 - 0.017 15.1 2.7 0.11 12.4 0.7 2.3 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin CorA PF01544.18 EGO57381.1 - 1.8e-26 93.1 1.5 4.2e-23 82.1 0.8 2.3 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein Carb_bind PF10645.9 EGO57382.1 - 3.4e-20 72.0 7.6 3.4e-20 72.0 7.6 1.8 2 0 0 2 2 2 1 Carbohydrate binding Methyltransf_2 PF00891.18 EGO57383.1 - 1.7e-24 86.3 0.0 2.5e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EGO57383.1 - 0.0012 19.5 0.0 0.0027 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO57383.1 - 0.0044 16.6 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_synthFbeta PF17759.1 EGO57383.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain TauD PF02668.16 EGO57384.1 - 1.4e-59 202.1 0.1 1.9e-59 201.6 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 EGO57385.1 - 2.4e-31 109.0 14.8 2.4e-31 109.0 14.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.6 EGO57385.1 - 4.9 7.7 6.5 4 8.0 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) FMO-like PF00743.19 EGO57386.1 - 2.6e-42 145.0 0.0 4.2e-19 68.4 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGO57386.1 - 6.2e-17 61.8 0.0 3.5e-11 42.9 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO57386.1 - 1e-11 44.7 0.0 2.8e-05 23.5 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO57386.1 - 2.2e-10 40.2 0.5 2.8e-06 26.7 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGO57386.1 - 4.2e-09 36.5 0.4 1.6e-08 34.7 0.0 2.1 2 1 1 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO57386.1 - 1.4e-07 31.4 6.5 1.2e-05 25.1 1.1 3.2 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGO57386.1 - 2.4e-07 30.9 1.7 0.00079 19.4 0.0 4.5 4 1 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EGO57386.1 - 1.9e-06 28.4 0.4 0.00067 20.2 0.3 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGO57386.1 - 4.6e-05 22.9 0.1 0.0024 17.2 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 EGO57386.1 - 0.0002 21.5 0.0 0.52 10.4 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 EGO57386.1 - 0.00084 18.8 0.0 0.0026 17.2 0.1 1.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGO57386.1 - 0.0013 18.0 0.2 0.021 14.1 0.2 2.1 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 EGO57386.1 - 0.0027 17.0 0.1 0.1 11.9 0.1 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EGO57386.1 - 0.003 16.7 0.8 0.0074 15.4 0.8 1.7 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EGO57386.1 - 0.0036 16.1 0.4 0.0098 14.6 0.7 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EGO57386.1 - 0.0079 15.5 0.3 0.015 14.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 EGO57386.1 - 0.11 12.9 0.0 9.3 6.7 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 EGO57386.1 - 0.12 11.3 0.4 4.1 6.1 0.3 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 EGO57386.1 - 0.13 12.2 0.6 0.25 11.2 0.6 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MCRA PF06100.11 EGO57386.1 - 0.17 10.7 0.0 1.2 7.9 0.0 1.9 2 0 0 2 2 2 0 MCRA family GIDA PF01134.22 EGO57386.1 - 0.21 10.6 2.2 0.3 10.1 1.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_2 PF03446.15 EGO57386.1 - 0.21 11.7 0.1 1.1 9.4 0.1 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF2293 PF10056.9 EGO57387.1 - 6.6e-30 103.2 0.6 6.6e-30 103.2 0.6 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) Peptidase_S46 PF10459.9 EGO57387.1 - 7.8 5.0 12.6 1.9 7.0 8.7 1.7 1 1 1 2 2 2 0 Peptidase S46 Scytalone_dh PF02982.14 EGO57388.1 - 1.2e-83 278.7 0.3 1.4e-83 278.5 0.3 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 EGO57388.1 - 0.00014 22.0 0.0 0.00024 21.2 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain MDM10 PF12519.8 EGO57389.1 - 1.4e-130 436.3 0.0 1.3e-111 373.8 0.0 2.2 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Ank_4 PF13637.6 EGO57390.1 - 7.9e-08 32.7 0.0 2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO57390.1 - 2.5e-06 28.0 0.0 5.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGO57390.1 - 4.2e-05 23.8 0.0 8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGO57390.1 - 7.1e-05 23.1 0.1 0.00081 19.7 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EGO57390.1 - 0.00057 20.1 0.0 0.012 16.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat DUF1843 PF08898.10 EGO57390.1 - 0.00062 20.2 0.1 0.016 15.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1843) Ribosomal_S19e PF01090.19 EGO57391.1 - 8.4e-60 200.4 0.1 9.5e-60 200.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ricin_B_lectin PF00652.22 EGO57392.1 - 4.3e-14 52.9 0.0 3.1e-06 27.4 0.0 4.0 3 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain Fe-S_biosyn PF01521.20 EGO57393.1 - 3.6e-07 30.3 0.0 0.0028 17.8 0.0 2.3 1 1 1 2 2 2 2 Iron-sulphur cluster biosynthesis Ribosomal_L30_N PF08079.12 EGO57394.1 - 9.4e-27 93.1 16.0 1.7e-26 92.2 16.0 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EGO57394.1 - 1.3e-17 63.4 2.1 1.3e-17 63.4 2.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_S11 PF00411.19 EGO57395.1 - 1.9e-46 157.0 1.2 2.4e-46 156.7 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EGO57395.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) BKACE PF05853.12 EGO57395.1 - 0.11 11.8 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme eIF-3c_N PF05470.12 EGO57396.1 - 1.5e-171 571.7 25.4 1.5e-171 571.7 25.4 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EGO57396.1 - 1.5e-13 51.1 0.0 6.9e-13 49.0 0.0 2.2 1 0 0 1 1 1 1 PCI domain DUF357 PF04010.13 EGO57396.1 - 0.1 12.7 0.1 0.37 10.9 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF357) DDE_Tnp_1_6 PF13751.6 EGO57396.1 - 0.13 12.5 1.8 0.39 11.0 1.8 1.8 1 0 0 1 1 1 0 Transposase DDE domain TFIIF_alpha PF05793.12 EGO57396.1 - 0.13 10.8 32.9 0.22 10.1 32.9 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DASH_Ask1 PF08655.10 EGO57396.1 - 0.42 10.5 2.2 0.96 9.4 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Ask1 CDC45 PF02724.14 EGO57396.1 - 0.55 8.5 25.9 0.9 7.8 25.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EGO57396.1 - 1.2 8.5 38.1 2.4 7.5 38.1 1.5 1 0 0 1 1 1 0 SDA1 PROCN PF08083.11 EGO57397.1 - 1.4e-233 774.9 9.3 1.4e-233 774.9 9.3 1.9 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EGO57397.1 - 3.1e-127 422.9 1.5 5.6e-127 422.1 1.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EGO57397.1 - 1.9e-89 297.7 3.5 9.4e-89 295.4 1.9 2.8 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EGO57397.1 - 6.2e-79 263.2 2.2 6.2e-79 263.2 2.2 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EGO57397.1 - 2.4e-71 238.1 0.1 5.4e-71 236.9 0.1 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EGO57397.1 - 2.3e-46 156.0 0.1 6.3e-46 154.6 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 EGO57397.1 - 2.1e-45 153.6 0.2 7.7e-45 151.8 0.0 2.1 2 0 0 2 2 2 1 PROCT (NUC072) domain Myb_DNA-bind_6 PF13921.6 EGO57398.1 - 7.2e-14 51.8 0.1 9.2e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGO57398.1 - 4.4e-13 49.2 0.1 1.1e-05 25.5 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4085 PF13315.6 EGO57398.1 - 0.03 14.0 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) ApbA_C PF08546.11 EGO57399.1 - 9.3e-41 138.9 0.0 1.6e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EGO57399.1 - 2.4e-30 105.2 0.0 4.2e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Exonuc_V_gamma PF04257.14 EGO57399.1 - 0.057 11.6 0.0 0.087 11.0 0.0 1.2 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit SNF2_N PF00176.23 EGO57400.1 - 4.8e-53 180.1 0.0 3.9e-48 164.0 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO57400.1 - 1.6e-20 73.5 0.0 3.3e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO57401.1 - 2.6e-50 170.6 0.0 4.8e-49 166.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO57401.1 - 3e-32 111.3 0.0 8.6e-32 109.8 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO57401.1 - 4.5e-05 23.5 0.0 0.00021 21.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 EGO57401.1 - 0.0022 16.9 0.0 0.25 10.1 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 EGO57401.1 - 0.02 15.2 0.0 9.2 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2443 PF10398.9 EGO57401.1 - 0.091 12.8 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Takusan PF04822.13 EGO57401.1 - 0.23 11.4 0.3 0.46 10.4 0.3 1.4 1 0 0 1 1 1 0 Takusan HET PF06985.11 EGO57402.1 - 2.9e-25 89.3 0.1 1.1e-24 87.4 0.1 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mpv17_PMP22 PF04117.12 EGO57404.1 - 3.8e-10 39.9 5.8 2.4e-09 37.3 4.8 2.1 1 1 1 2 2 2 1 Mpv17 / PMP22 family DER1 PF04511.15 EGO57404.1 - 0.0075 16.2 0.5 0.011 15.7 0.5 1.2 1 0 0 1 1 1 1 Der1-like family DUF3915 PF13054.6 EGO57404.1 - 1.8 8.5 3.3 3.5 7.6 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) EAP30 PF04157.16 EGO57405.1 - 2.9e-75 252.6 0.1 3.3e-75 252.4 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Utp12 PF04003.12 EGO57405.1 - 0.092 13.1 0.0 0.61 10.4 0.1 2.1 2 0 0 2 2 2 0 Dip2/Utp12 Family AAR2 PF05282.11 EGO57406.1 - 6.5e-35 121.2 0.1 2.4e-34 119.3 0.1 1.7 1 1 0 1 1 1 1 AAR2 protein DUF4604 PF15377.6 EGO57406.1 - 0.078 13.4 0.5 0.15 12.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) MCM_bind PF09739.9 EGO57408.1 - 0.1 11.0 1.7 0.13 10.6 1.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor FOXP-CC PF16159.5 EGO57408.1 - 0.13 12.9 0.2 0.26 11.9 0.2 1.5 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 EGO57408.1 - 0.17 12.4 0.2 0.35 11.4 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Phos_pyr_kin PF08543.12 EGO57409.1 - 1.2e-79 267.2 2.9 3.6e-79 265.6 2.9 1.8 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EGO57409.1 - 2.2e-49 168.1 0.3 3.3e-49 167.6 0.3 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 EGO57409.1 - 5.6e-07 29.1 0.1 0.00085 18.7 0.0 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase DUF2288 PF10052.9 EGO57409.1 - 0.067 13.3 0.2 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2288) UPF0444 PF15475.6 EGO57409.1 - 0.3 11.4 2.9 0.2 12.0 0.8 1.8 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 TPR_1 PF00515.28 EGO57410.1 - 7.8e-16 57.1 7.7 1.8e-08 33.9 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGO57410.1 - 2.1e-13 49.3 8.2 2.6e-06 27.1 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGO57410.1 - 3.3e-12 46.5 1.1 1.2e-07 32.0 0.1 2.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO57410.1 - 4.4e-10 39.0 4.2 4.1e-06 26.6 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGO57410.1 - 3e-08 33.8 3.0 0.028 15.0 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGO57410.1 - 1.2e-07 31.3 0.1 8.8e-06 25.4 0.1 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat PB1 PF00564.24 EGO57410.1 - 9.3e-07 28.7 0.1 1.7e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_11 PF13414.6 EGO57410.1 - 9.6e-07 28.4 3.5 5.4e-06 26.0 0.2 3.4 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.6 EGO57410.1 - 4.2e-05 24.1 0.4 0.0016 19.0 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGO57410.1 - 4.3e-05 23.6 3.1 0.13 12.4 0.1 2.8 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGO57410.1 - 5.4e-05 23.3 0.1 0.26 11.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGO57410.1 - 0.0066 16.3 2.3 0.12 12.3 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGO57410.1 - 0.0069 17.1 1.4 0.12 13.2 0.1 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 EGO57410.1 - 0.034 14.8 0.7 7.7 7.5 0.0 3.4 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGO57410.1 - 0.055 14.0 0.5 0.55 10.8 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.9 EGO57410.1 - 0.061 12.0 0.2 0.16 10.6 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) ANAPC5 PF12862.7 EGO57410.1 - 0.12 12.4 0.3 0.4 10.8 0.2 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 HMA PF00403.26 EGO57411.1 - 7.5e-14 51.9 0.0 1.9e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 EGO57411.1 - 4e-07 30.3 0.0 6.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Ribosomal_L13 PF00572.18 EGO57412.1 - 2e-40 137.9 0.0 3e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.18 EGO57413.1 - 4.9e-78 259.7 1.1 2.3e-41 141.1 0.3 2.0 2 0 0 2 2 2 2 Uricase DUF4295 PF14128.6 EGO57413.1 - 0.13 12.1 0.6 0.35 10.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4295) RICTOR_N PF14664.6 EGO57414.1 - 4.3e-134 447.2 0.3 3.5e-133 444.2 0.1 2.6 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 EGO57414.1 - 3.8e-39 133.4 0.1 7e-36 122.9 0.0 3.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 EGO57414.1 - 5.3e-36 122.6 0.1 1.5e-33 114.7 0.0 4.3 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 EGO57414.1 - 2.5e-29 101.3 0.3 1.1e-27 96.0 0.1 3.6 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 EGO57414.1 - 2.8e-14 53.0 10.7 8.9e-14 51.4 10.7 1.8 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.6 EGO57414.1 - 0.034 14.3 6.4 0.11 12.6 6.4 1.9 1 0 0 1 1 1 0 Up-regulated During Septation CENP-K PF11802.8 EGO57414.1 - 0.23 11.0 4.9 0.47 10.0 4.9 1.4 1 0 0 1 1 1 0 Centromere-associated protein K Spc7 PF08317.11 EGO57414.1 - 0.3 9.9 6.8 0.67 8.8 6.8 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein SOGA PF11365.8 EGO57414.1 - 0.31 12.2 5.1 1.3 10.2 5.1 2.1 1 0 0 1 1 1 0 Protein SOGA DUF724 PF05266.14 EGO57414.1 - 0.37 10.6 5.5 1.2 8.9 5.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF724) NdhL PF10716.9 EGO57415.1 - 0.55 10.2 6.1 1.9 8.5 2.4 2.4 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit HSBP1 PF06825.12 EGO57416.1 - 3.3e-05 23.6 1.1 0.0059 16.4 0.6 2.7 2 1 0 2 2 2 1 Heat shock factor binding protein 1 FAR1 PF03101.15 EGO57416.1 - 4.1e-05 24.2 0.4 4.1e-05 24.2 0.4 2.7 3 0 0 3 3 2 1 FAR1 DNA-binding domain XhlA PF10779.9 EGO57416.1 - 0.0012 19.0 0.4 0.11 12.7 0.2 2.6 2 0 0 2 2 2 1 Haemolysin XhlA DUF16 PF01519.16 EGO57416.1 - 0.0051 17.3 0.1 0.0051 17.3 0.1 3.4 4 0 0 4 4 4 1 Protein of unknown function DUF16 DUF853 PF05872.12 EGO57416.1 - 0.11 11.1 8.0 0.21 10.1 8.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF4407 PF14362.6 EGO57416.1 - 0.11 11.8 13.8 4.2 6.6 13.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AFT PF08731.11 EGO57416.1 - 0.24 11.8 0.2 0.24 11.8 0.2 3.1 3 0 0 3 3 3 0 Transcription factor AFT Sugarporin_N PF11471.8 EGO57416.1 - 0.53 10.3 0.0 0.53 10.3 0.0 3.5 3 0 0 3 3 2 0 Maltoporin periplasmic N-terminal extension EPL1 PF10513.9 EGO57416.1 - 1.3 9.4 19.4 0.048 14.0 6.2 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like LMBR1 PF04791.16 EGO57416.1 - 4.1 6.2 7.2 28 3.4 7.0 1.9 2 0 0 2 2 2 0 LMBR1-like membrane protein PPP4R2 PF09184.11 EGO57416.1 - 5.1 6.6 11.8 5.7 6.5 10.8 1.5 1 1 0 1 1 1 0 PPP4R2 PEP-utilisers_N PF05524.13 EGO57417.1 - 0.071 13.3 1.0 0.78 9.9 0.0 2.5 2 1 0 3 3 3 0 PEP-utilising enzyme, N-terminal Peptidase_M3_N PF08439.10 EGO57417.1 - 0.1 12.9 2.1 0.21 11.9 0.1 2.3 3 0 0 3 3 3 0 Oligopeptidase F Ribosomal_L34e PF01199.18 EGO57418.1 - 7.2e-44 148.0 3.2 1.1e-43 147.5 3.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 EGO57418.1 - 0.058 12.8 0.9 0.077 12.4 0.0 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FhuF_C PF11575.8 EGO57418.1 - 0.35 10.8 4.4 1.7 8.7 0.3 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain DUF498 PF04430.14 EGO57419.1 - 1.8e-29 102.0 0.0 2.4e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) CMAS PF02353.20 EGO57420.1 - 6e-64 216.0 0.1 7.7e-64 215.6 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGO57420.1 - 4.7e-11 42.8 0.0 8.3e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO57420.1 - 1.2e-10 41.9 0.0 2.9e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO57420.1 - 1.9e-09 38.1 0.0 4.5e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO57420.1 - 0.0012 19.5 0.0 0.0025 18.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EGO57420.1 - 0.011 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 MetW PF07021.12 EGO57420.1 - 0.094 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 EGO57420.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Alpha-amylase PF00128.24 EGO57421.1 - 6.1e-119 397.5 0.2 8.8e-119 397.0 0.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.8 EGO57421.1 - 1e-05 25.7 0.0 3e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3459) Malt_amylase_C PF16657.5 EGO57421.1 - 3.2e-05 24.0 0.0 8.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Glyco_hydro_42C PF08533.10 EGO57421.1 - 0.0086 15.8 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain hDGE_amylase PF14701.6 EGO57421.1 - 0.057 12.5 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Sugar_tr PF00083.24 EGO57422.1 - 1e-70 238.9 17.9 1.3e-70 238.5 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO57422.1 - 1.1e-14 54.1 33.7 2e-09 36.9 16.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGO57422.1 - 3e-07 29.4 23.5 0.0049 15.5 2.9 4.0 2 2 2 4 4 4 3 MFS/sugar transport protein G-patch_2 PF12656.7 EGO57423.1 - 3.1e-10 40.0 0.0 1.5e-09 37.8 0.0 2.3 1 0 0 1 1 1 1 G-patch domain PROL5-SMR PF15621.6 EGO57423.1 - 2.6 8.6 8.5 5.5 7.6 8.5 1.5 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Myb_DNA-bind_6 PF13921.6 EGO57424.1 - 6.7e-15 55.1 0.2 2.2e-14 53.4 0.2 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGO57424.1 - 1.5e-05 25.1 1.3 2.6e-05 24.3 0.2 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain WD40 PF00400.32 EGO57425.1 - 1.6e-10 41.3 0.1 0.77 10.7 0.2 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO57425.1 - 0.015 15.6 0.0 5 7.5 0.0 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Sec10 PF07393.11 EGO57425.1 - 0.06 11.8 1.0 0.087 11.2 1.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 efThoc1 PF11957.8 EGO57426.1 - 1.7e-135 452.5 4.2 2.5e-135 451.9 4.2 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 EGO57426.1 - 1.5e-23 83.4 0.0 3.4e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Guanylate kinase DUF2742 PF10888.8 EGO57426.1 - 0.05 13.9 0.3 0.19 12.0 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) Aquarius_N PF16399.5 EGO57427.1 - 0 1040.3 0.2 0 1039.0 0.2 1.6 1 1 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 EGO57427.1 - 1.3e-25 90.2 0.0 2.2e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGO57427.1 - 4e-20 72.7 0.0 1.2e-19 71.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGO57427.1 - 1.3e-06 28.3 0.0 0.00068 19.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 EGO57427.1 - 1.1e-05 25.5 0.0 3.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGO57427.1 - 2e-05 25.0 0.0 4.3e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO57427.1 - 0.00086 19.7 0.1 0.0062 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EGO57427.1 - 0.0016 18.8 0.0 0.005 17.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EGO57427.1 - 0.0067 16.2 0.1 0.52 10.0 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 EGO57427.1 - 0.0098 15.3 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 EGO57427.1 - 0.022 15.0 0.5 0.39 11.0 0.0 2.5 1 1 1 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 EGO57427.1 - 0.039 13.8 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 EGO57427.1 - 0.04 13.1 0.9 0.078 12.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 EGO57427.1 - 0.1 12.3 0.0 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 EGO57427.1 - 0.14 11.8 0.0 0.37 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 EGO57427.1 - 0.21 10.7 0.0 8.5 5.4 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Parvo_NS1 PF01057.17 EGO57427.1 - 0.21 10.6 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MIF4G PF02854.19 EGO57429.1 - 1.6e-53 181.5 0.0 2.9e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 EGO57429.1 - 4e-21 75.0 0.3 1.2e-20 73.5 0.3 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 HC2 PF07382.11 EGO57429.1 - 0.0026 17.9 50.0 0.0026 17.9 50.0 2.8 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 INSIG PF07281.12 EGO57430.1 - 6.3e-86 287.4 0.0 1.2e-85 286.5 0.0 1.5 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) DNA_pol_B PF00136.21 EGO57431.1 - 2.8e-118 395.5 0.5 4.2e-118 395.0 0.5 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EGO57431.1 - 6.4e-71 237.9 1.0 1.1e-70 237.2 1.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EGO57431.1 - 5.8e-41 140.7 0.0 8.9e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EGO57431.1 - 1.3e-21 76.4 12.2 1.3e-21 76.4 12.2 2.8 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 EGO57431.1 - 0.0012 17.8 0.4 0.032 13.1 0.0 2.4 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral PPR_2 PF13041.6 EGO57432.1 - 1.2e-22 79.9 1.8 6.7e-16 58.2 0.1 4.5 4 1 1 5 5 5 2 PPR repeat family PPR_long PF17177.4 EGO57432.1 - 2.3e-08 33.7 0.4 4e-06 26.4 0.8 2.3 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EGO57432.1 - 1e-07 31.7 0.4 0.00016 21.6 0.1 4.8 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 EGO57432.1 - 5.5e-07 29.6 0.5 0.015 15.4 0.1 2.8 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGO57432.1 - 0.00018 21.2 0.0 3.5 7.4 0.0 4.5 4 0 0 4 4 4 1 PPR repeat RPM2 PF08579.11 EGO57432.1 - 0.013 15.9 0.5 0.096 13.1 0.1 2.7 2 1 1 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) Pkinase PF00069.25 EGO57433.1 - 4.4e-50 170.5 0.1 1.7e-49 168.6 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57433.1 - 3.2e-23 82.3 0.0 5.9e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO57433.1 - 0.00037 20.5 3.3 0.00062 19.8 0.1 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGO57433.1 - 0.0043 16.7 0.2 0.011 15.4 0.2 1.6 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGO57433.1 - 0.79 9.3 2.7 0.4 10.2 0.2 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase TFIIA PF03153.13 EGO57433.1 - 1.2 9.1 61.9 0.24 11.4 25.6 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 EGO57434.1 - 0.12 12.5 5.1 0.13 12.3 5.1 1.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Androgen_recep PF02166.16 EGO57434.1 - 0.6 8.9 3.8 0.58 8.9 3.8 1.0 1 0 0 1 1 1 0 Androgen receptor RRM_1 PF00076.22 EGO57435.1 - 1.1e-58 195.0 0.1 1.8e-21 75.7 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO57435.1 - 5.7e-08 32.5 0.0 0.0057 16.5 0.0 4.1 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_5 PF13893.6 EGO57435.1 - 1.3e-07 31.2 0.0 0.31 10.6 0.0 4.2 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGO57435.1 - 7.8e-06 25.8 0.0 0.32 11.0 0.0 3.6 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EGO57435.1 - 3.5e-05 23.8 0.1 0.5 10.5 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif RRM_8 PF11835.8 EGO57435.1 - 0.0032 17.6 0.0 0.41 10.9 0.0 2.4 2 0 0 2 2 2 1 RRM-like domain Cas_Cas2CT1978 PF09707.10 EGO57435.1 - 0.069 13.2 0.0 15 5.8 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) Limkain-b1 PF11608.8 EGO57435.1 - 0.076 13.1 0.0 24 5.1 0.0 3.3 4 0 0 4 4 4 0 Limkain b1 SET_assoc PF11767.8 EGO57435.1 - 0.21 11.2 0.0 27 4.5 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated PH PF00169.29 EGO57437.1 - 8.9e-27 93.7 1.9 7.4e-15 55.4 0.1 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 EGO57437.1 - 3.5e-11 43.5 5.1 0.00019 21.8 0.6 3.4 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 EGO57437.1 - 4.9e-10 39.8 3.0 2.9e-05 24.4 0.4 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 EGO57437.1 - 0.0008 19.6 0.1 0.0024 18.1 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EGO57437.1 - 0.00081 19.5 0.8 0.027 14.6 0.2 2.4 2 0 0 2 2 2 1 PH domain PH_15 PF17339.2 EGO57437.1 - 0.39 10.6 1.3 12 5.8 0.1 2.3 2 0 0 2 2 2 0 PH domain CTU2 PF10288.9 EGO57438.1 - 9.1e-10 38.8 0.8 2e-08 34.5 0.0 3.3 3 1 0 3 3 3 1 Cytoplasmic tRNA 2-thiolation protein 2 Kv2channel PF03521.14 EGO57438.1 - 0.0073 15.7 0.7 0.015 14.7 0.7 1.4 1 0 0 1 1 1 1 Kv2 voltage-gated K+ channel ZapD PF07072.11 EGO57438.1 - 0.019 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Cell division protein RRM_1 PF00076.22 EGO57439.1 - 0.00013 21.8 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Roughex PF06020.11 EGO57439.1 - 0.47 9.5 2.6 0.72 8.9 2.6 1.3 1 0 0 1 1 1 0 Drosophila roughex protein TFIIA PF03153.13 EGO57439.1 - 3.3 7.6 10.5 5.3 6.9 10.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cation_efflux PF01545.21 EGO57440.1 - 3.9e-51 173.6 5.4 4.8e-51 173.3 5.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGO57440.1 - 0.00018 21.5 0.4 0.00038 20.5 0.4 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Pkinase PF00069.25 EGO57441.1 - 1.6e-62 211.3 0.0 2.4e-62 210.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57441.1 - 1.1e-29 103.5 0.0 2.2e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO57441.1 - 0.0018 17.6 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGO57441.1 - 0.004 16.5 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGO57441.1 - 0.019 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EGO57441.1 - 0.046 13.6 2.1 0.056 13.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3987 PF13148.6 EGO57441.1 - 0.53 9.2 8.6 0.76 8.7 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) LCD1 PF09798.9 EGO57441.1 - 1.9 6.9 6.0 0.9 8.0 3.5 1.6 2 0 0 2 2 2 0 DNA damage checkpoint protein Med3 PF11593.8 EGO57441.1 - 2 7.5 10.4 2.8 7.0 10.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MCM_bind PF09739.9 EGO57441.1 - 9.2 4.6 6.0 13 4.1 6.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF3617 PF12276.8 EGO57442.1 - 0.11 12.8 0.0 0.11 12.8 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3617) RRM_occluded PF16842.5 EGO57443.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Mito_carr PF00153.27 EGO57444.1 - 1e-54 182.4 3.6 5.4e-19 67.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGO57444.1 - 2.6 7.1 4.3 10 5.2 0.0 3.2 2 1 2 4 4 4 0 Gammaproteobacterial serine protease WD40 PF00400.32 EGO57445.1 - 7.2e-12 45.6 1.2 5.1e-06 27.1 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO57445.1 - 0.0047 17.2 0.0 28 5.1 0.0 4.0 3 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGO57445.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region SRP9-21 PF05486.12 EGO57446.1 - 1.6e-36 124.6 1.2 4.1e-36 123.3 1.2 1.6 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.21 EGO57447.1 - 1.3e-121 405.3 1.1 1.7e-121 405.0 1.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4112 PF13430.6 EGO57448.1 - 3.1e-35 120.6 0.6 4.1e-35 120.2 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DCP2 PF05026.13 EGO57449.1 - 7.2e-30 103.2 0.6 1.4e-29 102.3 0.6 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EGO57449.1 - 3e-15 56.4 0.0 6.5e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain FGGY_C PF02782.16 EGO57450.1 - 1e-24 87.4 0.0 2.7e-24 86.0 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGO57450.1 - 7.5e-19 68.3 0.0 9.3e-11 41.8 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Say1_Mug180 PF10340.9 EGO57451.1 - 4.8e-24 84.9 0.0 6.3e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 EGO57451.1 - 2.5e-23 83.1 0.0 3.4e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold CBFD_NFYB_HMF PF00808.23 EGO57452.1 - 1e-12 48.1 1.3 1.8e-12 47.4 1.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGO57452.1 - 0.0014 19.0 0.9 0.0014 19.0 0.9 2.7 1 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 Drf_FH1 PF06346.12 EGO57452.1 - 2.3 7.9 16.7 0.23 11.2 9.4 2.3 2 0 0 2 2 2 0 Formin Homology Region 1 AA_permease_2 PF13520.6 EGO57454.1 - 4.2e-88 296.0 27.6 5.9e-88 295.5 27.6 1.2 1 0 0 1 1 1 1 Amino acid permease PI3_PI4_kinase PF00454.27 EGO57455.1 - 2.7e-35 122.4 0.0 1.5e-34 120.0 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 EGO57455.1 - 1.6e-19 69.6 0.2 5.5e-19 67.9 0.2 2.0 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 EGO57455.1 - 0.07 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Fungal_trans PF04082.18 EGO57456.1 - 2.9e-28 98.7 0.0 5.2e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO57456.1 - 3.4e-09 36.7 10.8 5.3e-09 36.1 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VF530 PF09905.9 EGO57456.1 - 0.028 14.6 0.0 0.084 13.1 0.0 1.8 1 0 0 1 1 1 0 DNA-binding protein VF530 Kri1 PF05178.12 EGO57457.1 - 1.1e-29 103.1 21.8 1.1e-29 103.1 21.8 6.6 5 1 0 5 5 5 1 KRI1-like family Kri1_C PF12936.7 EGO57457.1 - 2.4e-27 95.0 0.9 2.4e-27 95.0 0.9 5.1 6 0 0 6 6 6 1 KRI1-like family C-terminal Ras PF00071.22 EGO57458.1 - 1.3e-57 193.9 0.0 1.6e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO57458.1 - 3.4e-34 117.6 0.0 4.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO57458.1 - 1.6e-13 50.4 0.0 2.6e-13 49.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGO57458.1 - 2.4e-05 24.0 0.0 4.4e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGO57458.1 - 8e-05 22.7 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGO57458.1 - 0.00015 21.2 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EGO57458.1 - 0.00076 19.9 0.0 0.0011 19.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGO57458.1 - 0.031 14.2 0.0 1.8 8.4 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase zf-C3HC4_3 PF13920.6 EGO57459.1 - 0.00038 20.3 11.0 0.00057 19.7 11.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EGO57459.1 - 0.26 11.2 4.0 0.42 10.5 4.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EGO57459.1 - 1.4 9.0 12.4 2.1 8.3 12.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Septin PF00735.18 EGO57460.1 - 2.3e-18 66.5 0.0 1.1e-14 54.4 0.0 2.2 2 0 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 EGO57460.1 - 0.00013 22.0 0.2 0.00093 19.3 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO57460.1 - 0.00071 19.5 0.0 0.029 14.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 EGO57460.1 - 0.0055 16.9 0.1 0.016 15.4 0.1 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EGO57460.1 - 0.0058 17.0 0.1 0.03 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 EGO57460.1 - 0.011 15.8 0.1 0.026 14.6 0.1 1.6 1 0 0 1 1 1 0 Dynamin family AAA PF00004.29 EGO57460.1 - 0.02 15.3 0.0 0.064 13.7 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EGO57460.1 - 0.021 15.4 0.0 0.065 13.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EGO57460.1 - 0.024 14.4 0.6 0.12 12.1 0.2 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain TsaE PF02367.17 EGO57460.1 - 0.031 14.3 0.0 0.092 12.7 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MCM PF00493.23 EGO57460.1 - 0.044 12.9 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain DUF815 PF05673.13 EGO57460.1 - 0.063 12.4 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 EGO57460.1 - 0.087 12.7 0.1 0.25 11.2 0.1 1.8 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 EGO57460.1 - 0.1 13.2 0.0 0.37 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGO57460.1 - 0.1 12.3 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGO57460.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EGO57460.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DnaJ PF00226.31 EGO57461.1 - 3.3e-07 30.3 0.3 3.3e-07 30.3 0.3 2.1 2 0 0 2 2 2 1 DnaJ domain BBP1_C PF15272.6 EGO57461.1 - 0.015 15.1 3.2 0.015 15.1 3.2 2.3 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Vma12 PF11712.8 EGO57461.1 - 0.64 10.1 0.0 0.64 10.1 0.0 2.6 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase HCMV_UL139 PF12507.8 EGO57461.1 - 3.7 7.9 13.0 0.1 13.0 2.8 2.8 2 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein DIOX_N PF14226.6 EGO57462.1 - 1.3e-24 87.3 0.1 2.2e-24 86.4 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGO57462.1 - 1.2e-20 73.8 0.0 2e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.14 EGO57463.1 - 4.8e-21 75.8 0.5 1.5e-20 74.1 0.5 1.9 1 1 0 1 1 1 1 Amidohydrolase DEAD PF00270.29 EGO57464.1 - 2.1e-39 135.1 0.0 4.2e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO57464.1 - 1e-29 103.1 0.0 2.1e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO57464.1 - 0.00046 20.2 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGO57464.1 - 0.13 12.5 0.1 2.9 8.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain CDC45 PF02724.14 EGO57464.1 - 0.17 10.1 19.5 0.27 9.5 19.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EGO57464.1 - 0.62 8.2 27.0 0.87 7.7 27.0 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 EGO57464.1 - 0.64 8.5 30.7 0.95 8.0 30.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 EGO57464.1 - 3.5 6.9 30.9 6 6.1 30.9 1.3 1 0 0 1 1 1 0 BUD22 Pkinase PF00069.25 EGO57465.1 - 1.8e-63 214.4 0.0 2.2e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57465.1 - 8.2e-37 126.9 0.0 1.2e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO57465.1 - 3.4e-07 29.9 0.0 5.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGO57465.1 - 0.00011 21.1 0.0 0.00016 20.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGO57465.1 - 0.0013 18.4 0.0 1.2 8.7 0.0 2.2 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGO57465.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EGO57465.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 EGO57465.1 - 0.22 11.0 0.0 0.34 10.4 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF3439 PF11921.8 EGO57466.1 - 0.47 10.4 4.5 0.68 9.9 2.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Pkinase PF00069.25 EGO57467.1 - 2e-41 142.1 0.0 4e-40 137.9 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57467.1 - 4.7e-18 65.4 0.0 2.7e-17 62.9 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO57467.1 - 0.00052 19.4 0.0 0.00069 19.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGO57467.1 - 0.0029 17.0 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGO57467.1 - 0.0031 16.5 0.0 0.0042 16.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EGO57467.1 - 0.2 10.6 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 EGO57468.1 - 4.2e-32 111.5 3.1 1.5e-19 70.4 0.0 3.5 2 2 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57468.1 - 8.5e-20 71.1 3.3 5.3e-15 55.4 0.0 3.2 2 1 1 3 3 3 2 Protein tyrosine kinase ROS_MUCR PF05443.11 EGO57468.1 - 3.2e-05 24.0 3.8 0.00018 21.5 1.8 2.7 2 0 0 2 2 2 1 ROS/MUCR transcriptional regulator protein Lin-8 PF03353.15 EGO57468.1 - 0.019 14.6 0.0 0.019 14.6 0.0 3.5 3 1 0 3 3 3 0 Ras-mediated vulval-induction antagonist zf-C2H2_2 PF12756.7 EGO57468.1 - 0.036 14.4 0.2 0.036 14.4 0.2 2.8 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EGO57468.1 - 0.26 11.8 1.4 0.89 10.1 1.2 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 EGO57468.1 - 0.79 10.4 9.5 0.082 13.6 3.0 2.7 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats LMBR1 PF04791.16 EGO57468.1 - 9.9 4.9 7.7 12 4.7 7.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Pkinase PF00069.25 EGO57469.1 - 4.9e-39 134.3 0.0 2.2e-34 119.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57469.1 - 1.3e-24 86.9 0.0 1.5e-19 70.3 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGO57469.1 - 1.9e-05 24.1 0.0 2.4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGO57469.1 - 0.00047 19.6 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO57469.1 - 0.012 15.5 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EGO57470.1 - 0.00011 21.6 0.7 0.01 15.1 0.2 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EGO57470.1 - 0.0003 20.3 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Rsm1 PF08600.10 EGO57470.1 - 0.059 13.5 0.1 1.7 8.8 0.1 2.4 2 0 0 2 2 2 0 Rsm1-like GCV_T PF01571.21 EGO57471.1 - 1.3e-12 47.7 0.0 2.1e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain CENP-B_dimeris PF09026.10 EGO57473.1 - 0.015 15.7 7.5 0.015 15.7 7.5 3.7 3 1 1 4 4 4 0 Centromere protein B dimerisation domain BUD22 PF09073.10 EGO57473.1 - 0.063 12.6 15.3 0.08 12.3 15.3 1.3 1 0 0 1 1 1 0 BUD22 GCP5-Mod21 PF14609.6 EGO57473.1 - 0.19 10.1 3.1 0.25 9.7 3.1 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 zf-C2H2_2 PF12756.7 EGO57474.1 - 4.9e-08 33.2 6.2 0.003 17.9 0.1 3.9 2 2 2 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EGO57474.1 - 1.7e-06 28.4 6.2 0.019 15.8 0.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO57474.1 - 7.6e-05 23.0 8.5 0.097 13.2 0.5 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 EGO57474.1 - 0.079 13.6 10.0 1.5 9.5 3.0 3.4 1 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats V_ATPase_I PF01496.19 EGO57474.1 - 0.4 8.5 14.7 0.46 8.4 14.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 EGO57474.1 - 0.54 9.6 14.2 0.69 9.2 14.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Asp-B-Hydro_N PF05279.11 EGO57474.1 - 1.6 8.8 23.2 2.2 8.3 23.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hid1 PF12722.7 EGO57474.1 - 7.5 4.5 13.5 9 4.3 13.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-3_zeta PF05091.12 EGO57474.1 - 8.1 5.3 16.2 11 4.9 16.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Atg14 PF10186.9 EGO57474.1 - 9.3 5.2 20.8 13 4.8 20.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pkinase PF00069.25 EGO57475.1 - 2.8e-44 151.5 0.0 3.2e-39 134.9 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57475.1 - 2.4e-20 72.9 0.0 1.6e-17 63.7 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EGO57475.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGO57475.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EGO57475.1 - 0.066 13.1 0.1 0.13 12.2 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGO57475.1 - 0.082 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Phage_Treg PF04761.12 EGO57475.1 - 0.19 11.8 0.0 0.52 10.5 0.0 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator TruD PF01142.18 EGO57476.1 - 1.1e-64 218.8 0.1 3.8e-59 200.6 0.0 3.6 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) Barttin PF15462.6 EGO57476.1 - 0.1 12.4 1.4 0.22 11.3 1.4 1.6 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) CH PF00307.31 EGO57477.1 - 6.8e-46 154.9 0.1 3e-22 78.9 0.0 3.2 4 0 0 4 4 4 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 EGO57477.1 - 1.8e-23 82.4 0.7 7.3e-23 80.5 0.1 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EGO57477.1 - 4.2e-10 39.3 0.7 5.1e-06 26.2 0.0 2.9 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.6 EGO57477.1 - 9.6e-05 22.0 0.7 0.00087 19.0 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 EGO57477.1 - 0.00028 21.3 1.5 0.00028 21.3 1.5 2.9 3 0 0 3 3 3 1 EF-hand domain pair Spectrin PF00435.21 EGO57477.1 - 0.0017 18.8 0.9 1.6 9.2 0.1 2.8 2 0 0 2 2 2 2 Spectrin repeat EF-hand_8 PF13833.6 EGO57477.1 - 0.003 17.4 0.7 0.034 14.0 0.1 2.8 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EGO57477.1 - 0.0031 16.9 0.2 0.068 12.7 0.0 2.7 2 0 0 2 2 2 1 EF hand Glyco_transf_90 PF05686.12 EGO57478.1 - 4.8e-15 55.4 9.7 1.5e-11 43.9 8.1 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ribosomal_S8 PF00410.19 EGO57479.1 - 1.1e-22 80.4 0.1 1.4e-22 80.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L7Ae PF01248.26 EGO57480.1 - 6.4e-28 96.3 0.8 8e-28 96.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1846 PF08903.11 EGO57480.1 - 0.058 11.9 0.1 0.11 11.0 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1846) PELOTA_1 PF15608.6 EGO57480.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Rotamase_3 PF13616.6 EGO57481.1 - 7.4e-20 71.6 0.2 1.6e-19 70.6 0.2 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EGO57481.1 - 4.8e-17 62.7 0.1 6.9e-17 62.2 0.1 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EGO57481.1 - 1.5e-06 29.1 0.2 2.1e-06 28.6 0.2 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain VPS9 PF02204.18 EGO57483.1 - 3e-24 85.2 0.0 5.5e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EGO57483.1 - 0.023 15.0 0.0 0.089 13.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) Lipase_3 PF01764.25 EGO57484.1 - 1.9e-07 31.1 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 EGO57484.1 - 0.0079 15.9 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO57484.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UPF0227 PF05728.12 EGO57484.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 EGO57484.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 EGO57484.1 - 1.9 9.1 8.8 0.31 11.6 2.1 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family zf-C3HC4 PF00097.25 EGO57485.1 - 1.5e-06 27.9 2.7 1.5e-06 27.9 2.7 5.4 7 0 0 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO57485.1 - 8.2e-06 25.6 3.2 8.2e-06 25.6 3.2 4.6 7 1 0 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO57485.1 - 1.7e-05 24.8 0.8 1.7e-05 24.8 0.8 4.6 5 0 0 5 5 5 1 RING-type zinc-finger zf-RING_6 PF14835.6 EGO57485.1 - 0.0023 17.8 0.3 0.0023 17.8 0.3 2.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EGO57485.1 - 0.01 15.8 4.1 0.01 15.8 4.1 5.3 7 0 0 7 7 7 0 zinc-RING finger domain zf-RING_2 PF13639.6 EGO57485.1 - 0.013 15.8 6.2 0.013 15.8 6.2 5.7 4 2 1 5 5 5 0 Ring finger domain SH3_1 PF00018.28 EGO57485.1 - 0.13 11.8 0.2 0.27 10.9 0.2 1.5 1 0 0 1 1 1 0 SH3 domain ERCC3_RAD25_C PF16203.5 EGO57486.1 - 1.1e-120 401.4 0.4 2e-120 400.6 0.4 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EGO57486.1 - 3.7e-32 111.2 0.0 9.9e-32 109.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO57486.1 - 1e-17 64.7 0.0 2e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGO57486.1 - 1e-11 45.2 0.1 4.4e-11 43.1 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EGO57486.1 - 2.3e-08 33.2 0.0 3.1e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EGO57486.1 - 0.0017 18.1 0.0 0.0048 16.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-CHY PF05495.12 EGO57487.1 - 1.7e-12 47.6 18.4 3.5e-12 46.6 18.4 1.5 1 0 0 1 1 1 1 CHY zinc finger Zn_ribbon_SprT PF17283.2 EGO57487.1 - 0.0026 17.6 4.8 0.058 13.3 0.7 2.5 2 0 0 2 2 2 2 SprT-like zinc ribbon domain Cys_rich_KTR PF14205.6 EGO57487.1 - 0.0092 15.8 7.5 1.2 9.0 0.0 2.6 1 1 1 2 2 2 2 Cysteine-rich KTR zinc_ribbon_4 PF13717.6 EGO57487.1 - 0.41 10.6 11.3 10 6.1 1.2 4.0 4 0 0 4 4 4 0 zinc-ribbon domain DUF3797 PF12677.7 EGO57487.1 - 0.55 10.2 0.0 0.55 10.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) Zn_Tnp_IS91 PF14319.6 EGO57487.1 - 2.4 8.3 15.1 0.3 11.1 3.6 2.3 1 1 1 2 2 2 0 Transposase zinc-binding domain zf-LITAF-like PF10601.9 EGO57487.1 - 4.1 7.7 12.0 86 3.5 11.7 2.8 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain HypA PF01155.19 EGO57487.1 - 5.9 6.9 13.7 0.2 11.7 4.3 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Proteasome PF00227.26 EGO57488.1 - 6.3e-56 188.9 0.1 1e-55 188.2 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGO57488.1 - 1.1e-11 44.1 0.4 3.6e-11 42.5 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FAD-oxidase_C PF02913.19 EGO57489.1 - 4.8e-62 209.8 0.0 6.3e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGO57489.1 - 1.1e-37 128.9 0.2 2.3e-37 127.8 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain B277 PF17623.2 EGO57490.1 - 0.55 9.3 2.1 0.85 8.6 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function Voltage_CLC PF00654.20 EGO57491.1 - 8.8e-88 294.9 27.0 8.8e-88 294.9 27.0 1.9 3 0 0 3 3 3 1 Voltage gated chloride channel CBS PF00571.28 EGO57491.1 - 0.0007 20.0 0.0 0.19 12.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain Paf1 PF03985.13 EGO57492.1 - 8.4e-85 285.3 4.1 9.5e-85 285.1 4.1 1.0 1 0 0 1 1 1 1 Paf1 Rer1 PF03248.13 EGO57493.1 - 4e-79 264.3 6.5 4.7e-79 264.1 6.5 1.0 1 0 0 1 1 1 1 Rer1 family DUF1538 PF07556.11 EGO57493.1 - 0.048 13.0 1.0 0.71 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1538) CAML PF14963.6 EGO57493.1 - 0.96 9.5 3.0 0.98 9.5 0.1 2.1 2 1 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand ECH_1 PF00378.20 EGO57494.1 - 7.2e-76 254.8 0.1 8.3e-76 254.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGO57494.1 - 9.5e-34 117.4 0.2 1.2e-32 113.7 0.2 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HA70_C PF17993.1 EGO57494.1 - 0.059 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Haemagglutinin 70 C-terminal domain TrkH PF02386.16 EGO57495.1 - 3.3e-136 454.7 10.8 1.5e-134 449.2 3.8 2.1 2 0 0 2 2 2 2 Cation transport protein Ribosomal_L19 PF01245.20 EGO57496.1 - 2.1e-12 47.0 0.2 3.3e-12 46.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 Cytochrom_B558a PF05038.13 EGO57496.1 - 0.077 12.6 0.2 0.18 11.3 0.2 1.6 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit PALP PF00291.25 EGO57498.1 - 6.7e-69 232.5 0.2 7.8e-69 232.3 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme YL1 PF05764.13 EGO57499.1 - 2.9e-70 237.2 29.3 2.9e-70 237.2 29.3 4.3 4 0 0 4 4 4 1 YL1 nuclear protein YL1_C PF08265.11 EGO57499.1 - 7.7e-09 35.2 2.1 1.5e-08 34.3 2.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Ras PF00071.22 EGO57500.1 - 5.9e-52 175.5 0.0 6.8e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO57500.1 - 3.4e-18 66.0 0.0 5.2e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO57500.1 - 3.3e-08 33.2 0.0 4.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RVT_1 PF00078.27 EGO57502.1 - 0.0016 18.0 0.5 0.0017 17.9 0.5 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arginase PF00491.21 EGO57505.1 - 1.1e-75 254.7 0.0 1.8e-71 240.9 0.0 2.0 1 1 1 2 2 2 2 Arginase family UPF0489 PF12640.7 EGO57505.1 - 0.013 15.7 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 UPF0489 domain tRNA-synt_2 PF00152.20 EGO57506.1 - 3.3e-85 285.9 0.1 4.8e-85 285.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGO57506.1 - 6.5e-08 32.5 0.0 1.4e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain FapA PF03961.13 EGO57506.1 - 0.02 13.5 3.1 0.028 13.0 1.0 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A KfrA_N PF11740.8 EGO57506.1 - 0.051 14.2 1.6 0.11 13.2 1.6 1.6 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term tRNA-synt_2d PF01409.20 EGO57506.1 - 0.056 12.9 0.1 0.37 10.2 0.1 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Metallophos_2 PF12850.7 EGO57506.1 - 0.15 12.3 0.1 0.41 10.8 0.1 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF4795 PF16043.5 EGO57506.1 - 0.24 11.0 5.4 2.6 7.6 1.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) RRM_1 PF00076.22 EGO57509.1 - 9e-38 127.9 0.1 1.8e-11 43.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGO57509.1 - 1.1e-15 57.2 0.0 0.0095 15.8 0.0 4.4 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 EGO57509.1 - 2.4e-07 30.4 7.3 2.4e-07 30.4 7.3 3.6 3 1 1 4 4 4 1 Putative RRM domain DUF4523 PF15023.6 EGO57509.1 - 6.4e-06 26.1 0.0 0.026 14.3 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 EGO57509.1 - 1.8e-05 24.8 0.0 0.12 12.5 0.0 3.8 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 EGO57509.1 - 0.0033 17.4 0.1 0.17 12.0 0.1 2.8 3 0 0 3 3 3 1 RNA binding motif RRM_Rrp7 PF17799.1 EGO57509.1 - 0.0085 15.9 0.0 1.1 9.0 0.0 3.5 2 1 1 3 3 3 1 Rrp7 RRM-like N-terminal domain RNA_bind PF08675.11 EGO57509.1 - 0.042 13.9 0.3 0.29 11.2 0.0 2.5 4 0 0 4 4 4 0 RNA binding domain Nup35_RRM_2 PF14605.6 EGO57509.1 - 0.096 12.7 0.0 32 4.6 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif His_Phos_2 PF00328.22 EGO57510.1 - 3e-14 53.2 0.0 1.8e-10 40.7 0.0 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) PPR_2 PF13041.6 EGO57511.1 - 1.8e-23 82.5 0.6 6.4e-11 42.3 0.0 5.5 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.6 EGO57511.1 - 1.1e-12 47.8 0.0 3.4e-08 33.4 0.0 3.3 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 EGO57511.1 - 2.6e-11 43.0 4.6 0.049 13.9 0.0 6.2 6 0 0 6 6 6 4 PPR repeat PPR_1 PF12854.7 EGO57511.1 - 2.5e-09 36.6 0.0 3.4e-05 23.4 0.0 5.4 6 0 0 6 6 6 1 PPR repeat PPR_long PF17177.4 EGO57511.1 - 4.9e-08 32.6 0.5 0.00033 20.1 0.1 4.1 3 1 2 5 5 5 2 Pentacotripeptide-repeat region of PRORP Ribosomal_60s PF00428.19 EGO57512.1 - 3.2 8.4 4.9 14 6.4 4.9 2.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Mis12 PF05859.12 EGO57513.1 - 7.2e-50 168.6 0.2 3.2e-49 166.4 0.0 2.0 2 0 0 2 2 2 1 Mis12 protein TCTP PF00838.17 EGO57514.1 - 4.4e-70 235.3 3.9 4.9e-70 235.2 3.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein NAPRTase PF04095.16 EGO57514.1 - 0.055 13.1 0.2 0.1 12.2 0.2 1.4 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family FA_hydroxylase PF04116.13 EGO57515.1 - 1.4e-21 77.3 12.0 2.4e-21 76.5 12.0 1.4 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily AAA_5 PF07728.14 EGO57517.1 - 6.7e-116 382.5 0.0 1.6e-21 76.7 0.0 8.7 8 0 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EGO57517.1 - 9.7e-52 173.6 8.2 1.5e-20 73.3 0.0 5.8 6 0 0 6 6 4 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 EGO57517.1 - 1.7e-31 108.4 0.6 3.9e-30 104.0 0.1 3.1 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_3 PF07726.11 EGO57517.1 - 3.4e-28 98.1 0.0 1.1e-09 38.2 0.0 6.1 6 0 0 6 6 5 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EGO57517.1 - 2.3e-24 86.3 0.0 6.5e-05 23.4 0.0 6.1 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGO57517.1 - 2.1e-23 83.6 26.7 5.1e-05 23.7 0.0 9.6 7 2 1 8 8 6 5 AAA ATPase domain Dynein_heavy PF03028.15 EGO57517.1 - 5.8e-23 81.2 0.0 0.0043 17.1 0.0 8.0 7 0 0 7 7 7 4 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 EGO57517.1 - 1.3e-21 77.0 0.2 4.9e-05 22.9 0.0 6.3 6 0 0 6 6 6 5 P-loop containing dynein motor region AAA_22 PF13401.6 EGO57517.1 - 3.3e-18 66.3 8.0 0.0021 18.3 0.0 8.6 9 0 0 9 9 6 5 AAA domain AAA_6 PF12774.7 EGO57517.1 - 4.1e-18 65.4 0.0 0.0038 16.2 0.0 7.3 8 0 0 8 8 6 4 Hydrolytic ATP binding site of dynein motor region AAA_14 PF13173.6 EGO57517.1 - 6.1e-17 61.9 0.0 0.0015 18.6 0.0 7.0 6 0 0 6 6 6 4 AAA domain AAA_33 PF13671.6 EGO57517.1 - 1.3e-16 61.1 0.3 0.017 15.2 0.0 6.6 6 0 0 6 6 5 4 AAA domain Sigma54_activat PF00158.26 EGO57517.1 - 2.9e-16 59.6 0.0 0.018 14.8 0.0 5.8 6 0 0 6 6 5 4 Sigma-54 interaction domain AAA_18 PF13238.6 EGO57517.1 - 8.9e-15 55.4 6.1 0.0074 16.8 0.0 7.1 7 0 0 7 7 5 4 AAA domain TsaE PF02367.17 EGO57517.1 - 1.6e-13 50.7 2.9 0.0026 17.8 0.1 5.4 5 0 0 5 5 5 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EGO57517.1 - 1.8e-13 50.6 0.1 0.066 12.9 0.0 7.1 6 0 0 6 6 6 1 AAA domain RsgA_GTPase PF03193.16 EGO57517.1 - 3.7e-13 49.7 0.4 0.056 13.4 0.1 5.6 5 0 0 5 5 5 4 RsgA GTPase NACHT PF05729.12 EGO57517.1 - 7.9e-13 48.7 2.5 0.058 13.3 0.0 5.3 4 0 0 4 4 4 4 NACHT domain T2SSE PF00437.20 EGO57517.1 - 1.4e-11 43.9 1.1 0.022 13.8 0.0 5.5 5 0 0 5 5 5 2 Type II/IV secretion system protein RNA_helicase PF00910.22 EGO57517.1 - 4e-11 43.3 0.2 1.3 9.5 0.0 5.7 5 0 0 5 5 5 2 RNA helicase Zeta_toxin PF06414.12 EGO57517.1 - 9.1e-11 41.4 0.5 0.048 12.9 0.0 5.9 5 0 0 5 5 5 1 Zeta toxin Sigma54_activ_2 PF14532.6 EGO57517.1 - 7.4e-10 39.1 0.3 0.004 17.3 0.1 5.4 5 0 0 5 5 5 2 Sigma-54 interaction domain ATPase_2 PF01637.18 EGO57517.1 - 1.4e-09 38.3 0.0 0.024 14.5 0.0 5.3 5 0 0 5 5 4 2 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EGO57517.1 - 1.5e-09 37.5 1.3 0.59 9.5 0.0 7.0 7 0 0 7 7 7 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGO57517.1 - 2.4e-09 37.7 0.8 1.8 8.8 0.0 6.2 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.6 EGO57517.1 - 3.5e-09 36.2 0.1 0.29 10.9 0.0 5.5 5 0 0 5 5 5 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EGO57517.1 - 1e-08 35.8 16.0 0.15 12.6 0.0 7.8 8 0 0 8 8 6 3 ABC transporter IstB_IS21 PF01695.17 EGO57517.1 - 1.8e-08 34.3 0.1 0.73 9.5 0.0 5.4 5 0 0 5 5 5 2 IstB-like ATP binding protein RuvB_N PF05496.12 EGO57517.1 - 1.1e-07 31.7 1.8 1.7 8.4 0.0 5.5 5 0 0 5 5 5 2 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EGO57517.1 - 2.2e-07 30.7 1.3 1.1 8.8 0.0 5.0 4 0 0 4 4 4 1 AAA domain Rad17 PF03215.15 EGO57517.1 - 3.7e-07 30.3 0.3 0.19 11.7 0.0 5.4 5 0 0 5 5 5 1 Rad17 P-loop domain SRP54 PF00448.22 EGO57517.1 - 3.3e-06 26.9 1.2 0.95 9.1 0.1 5.2 5 0 0 5 5 5 1 SRP54-type protein, GTPase domain Roc PF08477.13 EGO57517.1 - 3.9e-06 27.1 0.5 11 6.3 0.0 5.5 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 EGO57517.1 - 4.1e-06 27.2 4.1 3 8.2 0.1 5.6 5 0 0 5 5 4 0 AAA domain NTPase_1 PF03266.15 EGO57517.1 - 5e-06 26.5 1.9 1.7 8.5 0.0 4.7 4 0 0 4 4 4 2 NTPase AAA_24 PF13479.6 EGO57517.1 - 5.5e-06 26.2 0.5 8 6.1 0.0 6.2 6 0 0 6 6 6 0 AAA domain dNK PF01712.19 EGO57517.1 - 1.1e-05 25.3 1.3 1.7 8.4 0.0 4.9 4 0 0 4 4 4 1 Deoxynucleoside kinase MMR_HSR1 PF01926.23 EGO57517.1 - 1.6e-05 24.9 0.8 18 5.5 0.0 5.7 5 0 0 5 5 5 0 50S ribosome-binding GTPase cobW PF02492.19 EGO57517.1 - 1.7e-05 24.5 3.1 3.2 7.3 0.0 5.5 5 0 0 5 5 5 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 EGO57517.1 - 2.3e-05 23.9 0.3 1.7 8.1 0.0 5.4 6 0 0 6 6 5 1 Bacterial TniB protein CbiA PF01656.23 EGO57517.1 - 2.4e-05 24.4 0.1 3.5 7.7 0.0 4.9 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF815 PF05673.13 EGO57517.1 - 4.5e-05 22.7 1.8 3.9 6.5 0.0 5.3 6 0 0 6 6 6 0 Protein of unknown function (DUF815) TIP49 PF06068.13 EGO57517.1 - 0.00011 21.5 0.2 2.3 7.3 0.0 4.3 5 0 0 5 5 5 1 TIP49 P-loop domain Bac_DnaA PF00308.18 EGO57517.1 - 0.00044 20.1 0.8 11 5.7 0.0 4.8 5 0 0 5 5 5 0 Bacterial dnaA protein NB-ARC PF00931.22 EGO57517.1 - 0.00065 19.0 0.4 11 5.1 0.0 4.5 4 0 0 4 4 4 0 NB-ARC domain ResIII PF04851.15 EGO57517.1 - 0.00068 19.7 0.0 4.2 7.3 0.0 5.2 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit VWA_2 PF13519.6 EGO57517.1 - 0.00083 20.0 0.1 0.0043 17.7 0.1 2.4 1 0 0 1 1 1 1 von Willebrand factor type A domain ATP_bind_1 PF03029.17 EGO57517.1 - 0.0017 18.2 0.7 29 4.3 0.0 4.8 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein CPT PF07931.12 EGO57517.1 - 0.0019 18.1 0.2 38 4.1 0.0 5.2 5 1 0 5 5 3 0 Chloramphenicol phosphotransferase-like protein Viral_helicase1 PF01443.18 EGO57517.1 - 0.0025 17.6 0.0 6.9 6.3 0.0 4.2 5 0 0 5 5 4 0 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 EGO57517.1 - 0.0028 17.0 0.1 1 8.6 0.0 3.4 3 0 0 3 3 2 1 DnaB-like helicase C terminal domain SRPRB PF09439.10 EGO57517.1 - 0.0059 16.1 0.5 26 4.2 0.0 5.0 5 0 0 5 5 5 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGO57517.1 - 0.0096 15.7 2.3 7.8 6.2 0.1 4.6 5 0 0 5 5 5 0 Ethanolamine utilisation - propanediol utilisation APS_kinase PF01583.20 EGO57517.1 - 0.0097 15.8 0.6 1.3 8.9 0.0 4.2 5 0 0 5 5 3 1 Adenylylsulphate kinase MobB PF03205.14 EGO57517.1 - 0.012 15.5 1.2 22 5.0 0.0 4.7 5 0 0 5 5 5 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.14 EGO57517.1 - 0.017 14.4 0.3 16 4.6 0.0 4.7 5 0 0 5 5 5 0 KAP family P-loop domain DAP3 PF10236.9 EGO57517.1 - 0.04 13.1 4.2 1.2 8.2 0.0 4.2 5 0 0 5 5 4 0 Mitochondrial ribosomal death-associated protein 3 ATPase PF06745.13 EGO57517.1 - 0.093 12.1 0.4 35 3.7 0.0 3.9 4 0 0 4 4 3 0 KaiC Cytidylate_kin PF02224.18 EGO57517.1 - 0.11 12.2 0.6 1.5e+02 2.0 0.1 4.3 4 0 0 4 4 4 0 Cytidylate kinase MeaB PF03308.16 EGO57517.1 - 0.12 11.3 2.7 3.4 6.6 0.1 3.1 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ribosomal_L12 PF00542.19 EGO57518.1 - 8.9e-22 77.2 7.1 7.1e-21 74.3 6.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EGO57518.1 - 2.3e-11 43.2 15.3 2.3e-11 43.2 15.3 3.5 4 1 0 4 4 4 1 Ribosomal protein L7/L12 dimerisation domain SpoVIF PF14069.6 EGO57518.1 - 0.22 11.3 1.7 0.24 11.2 0.2 1.8 2 1 0 2 2 2 0 Stage VI sporulation protein F CTK3 PF12243.8 EGO57519.1 - 8.1e-52 174.4 0.4 1.4e-51 173.6 0.4 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EGO57519.1 - 1.7e-16 60.1 13.5 4.7e-16 58.7 13.5 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Rcd1 PF04078.13 EGO57519.1 - 0.046 13.0 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like Methyltrans_RNA PF04452.14 EGO57519.1 - 0.075 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA methyltransferase Imm1 PF14430.6 EGO57519.1 - 0.079 13.6 0.4 0.2 12.3 0.1 1.8 2 0 0 2 2 2 0 Immunity protein Imm1 DUF1180 PF06679.12 EGO57519.1 - 4.5 7.7 13.4 0.28 11.6 4.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) P5CR_dimer PF14748.6 EGO57520.1 - 2.2e-34 117.8 4.7 3.9e-34 117.0 4.7 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EGO57520.1 - 2.9e-08 34.2 1.1 6.7e-06 26.6 0.2 2.9 2 1 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Hat1_N PF10394.9 EGO57521.1 - 5.3e-47 160.0 0.1 8.5e-47 159.4 0.1 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 EGO57521.1 - 0.0078 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO57521.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Zip PF02535.22 EGO57522.1 - 2e-36 125.9 16.8 6.5e-30 104.5 6.5 2.5 1 1 1 2 2 2 2 ZIP Zinc transporter DUF4818 PF16089.5 EGO57522.1 - 0.05 14.1 0.7 1.5 9.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4818) DUF2085 PF09858.9 EGO57522.1 - 1.7 9.2 5.2 2.4 8.7 1.2 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2085) IR1-M PF12185.8 EGO57524.1 - 0.044 13.7 0.1 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain DUF678 PF05077.12 EGO57525.1 - 0.0069 16.5 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF678) Methyltransf_23 PF13489.6 EGO57531.1 - 3.2e-17 62.9 0.0 4.2e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO57531.1 - 3.9e-09 37.1 0.0 9.7e-09 35.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO57531.1 - 1.5e-08 35.1 0.0 3.1e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO57531.1 - 1.4e-05 25.7 0.0 9.1e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO57531.1 - 0.0001 22.1 0.0 0.22 11.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 EGO57531.1 - 0.00027 20.4 0.1 0.0057 16.0 0.1 2.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EGO57531.1 - 0.031 14.0 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 EGO57531.1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 EGO57531.1 - 0.061 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 EGO57531.1 - 0.084 13.0 0.2 0.89 9.6 0.2 2.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase HET PF06985.11 EGO57532.1 - 1.5e-27 96.8 0.0 2.9e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DNA_ligase_A_M PF01068.21 EGO57534.1 - 6.9e-60 202.2 0.2 9.7e-58 195.2 0.2 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGO57534.1 - 1.6e-43 149.1 2.0 1.6e-43 149.1 0.0 2.1 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGO57534.1 - 5.6e-29 100.7 0.0 2.8e-28 98.4 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EGO57534.1 - 3e-05 24.4 0.1 4.9e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 RNA ligase Spore_coat_CotO PF14153.6 EGO57534.1 - 0.0018 18.3 1.4 0.0031 17.5 1.4 1.4 1 0 0 1 1 1 1 Spore coat protein CotO MctB PF11382.8 EGO57534.1 - 0.018 14.8 0.1 0.018 14.8 0.1 2.1 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB DNA_ligase_OB_2 PF14743.6 EGO57534.1 - 0.057 13.4 0.0 4.4 7.4 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain FXMRP1_C_core PF12235.8 EGO57534.1 - 0.71 10.5 4.8 1.6 9.4 4.8 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal DUF4746 PF15928.5 EGO57534.1 - 2.5 7.5 10.7 4.7 6.5 10.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) E1_dh PF00676.20 EGO57535.1 - 5.1e-114 380.3 0.2 6e-114 380.0 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EGO57535.1 - 0.0047 16.2 0.1 0.009 15.3 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase WD40 PF00400.32 EGO57536.1 - 3.1e-38 129.1 24.3 3.5e-07 30.8 0.2 7.1 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 EGO57536.1 - 3.4e-14 52.5 0.4 6.5e-14 51.6 0.4 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EGO57536.1 - 5.5e-09 36.2 3.6 0.1 12.9 0.0 6.0 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO57536.1 - 2.2e-07 30.0 9.9 0.13 10.9 0.1 5.4 3 1 3 6 6 6 4 Nucleoporin Nup120/160 F-box PF00646.33 EGO57536.1 - 1.3e-05 24.9 2.0 3.2e-05 23.7 2.0 1.7 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 EGO57536.1 - 9.6e-05 21.9 0.3 0.0002 20.9 0.3 1.5 1 0 0 1 1 1 1 F-box WD40_like PF17005.5 EGO57536.1 - 0.00094 18.6 0.0 1.1 8.6 0.0 2.6 3 0 0 3 3 3 2 WD40-like domain PQQ_2 PF13360.6 EGO57536.1 - 0.013 15.1 6.1 0.72 9.4 0.3 3.5 1 1 3 5 5 5 0 PQQ-like domain BBS2_Mid PF14783.6 EGO57536.1 - 0.081 13.0 0.3 41 4.3 0.0 3.6 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region AAA PF00004.29 EGO57537.1 - 3.6e-50 169.8 0.0 5.8e-42 143.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO57537.1 - 1.9e-09 37.2 0.0 5.1e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 EGO57537.1 - 3e-06 27.1 0.0 2.4e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 EGO57537.1 - 2.6e-05 24.4 0.0 7.3e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGO57537.1 - 0.00059 20.3 4.3 0.00086 19.7 0.2 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EGO57537.1 - 0.0024 17.9 0.1 0.015 15.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGO57537.1 - 0.0024 18.1 0.2 0.069 13.4 0.2 2.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO57537.1 - 0.0068 16.9 0.1 0.046 14.3 0.0 2.5 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 EGO57537.1 - 0.0072 16.5 0.0 0.04 14.1 0.0 2.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGO57537.1 - 0.014 15.2 0.0 0.038 13.7 0.0 1.7 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EGO57537.1 - 0.015 15.7 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 EGO57537.1 - 0.017 14.4 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Bromodomain PF00439.25 EGO57537.1 - 0.022 14.8 0.1 0.056 13.5 0.1 1.6 1 0 0 1 1 1 0 Bromodomain AAA_7 PF12775.7 EGO57537.1 - 0.11 11.9 0.0 0.46 10.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 EGO57537.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 EGO57537.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGO57537.1 - 0.17 11.8 0.0 0.45 10.4 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 EGO57537.1 - 0.72 9.2 4.9 0.2 11.0 0.2 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_pol_I_A49 PF06870.12 EGO57538.1 - 1.4e-106 356.7 2.5 1.7e-106 356.3 2.5 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Arfaptin PF06456.13 EGO57538.1 - 0.12 11.9 4.4 6.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Arfaptin-like domain MafB PF06255.13 EGO57538.1 - 0.18 11.2 1.6 0.26 10.7 1.6 1.2 1 0 0 1 1 1 0 Neisseria toxin MafB Pkinase PF00069.25 EGO57541.1 - 8.3e-58 195.8 0.0 1.3e-57 195.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57541.1 - 3.3e-23 82.3 0.0 2.4e-22 79.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.26 EGO57541.1 - 6.5e-13 48.8 0.5 1.6e-12 47.6 0.5 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 EGO57541.1 - 1.7e-07 30.9 0.0 0.013 14.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Yop-YscD_cpl PF16697.5 EGO57541.1 - 2.8e-06 27.6 0.0 1.3e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-C2H2 PF00096.26 EGO57542.1 - 1.3e-07 31.7 10.7 0.0055 17.1 2.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type YpzI PF14140.6 EGO57542.1 - 0.091 12.5 0.6 0.24 11.2 0.6 1.7 1 0 0 1 1 1 0 YpzI-like protein zf-Di19 PF05605.12 EGO57542.1 - 0.3 11.4 5.9 0.34 11.2 1.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EGO57542.1 - 0.83 10.7 15.0 0.12 13.3 1.7 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGO57542.1 - 2.3 8.8 18.2 3 8.4 0.2 4.0 5 0 0 5 5 5 0 Zinc-finger double domain SNF2_N PF00176.23 EGO57543.1 - 3.5e-73 246.3 0.8 3.5e-73 246.3 0.8 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO57543.1 - 7.1e-21 74.6 0.4 2.2e-18 66.6 0.0 3.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 EGO57543.1 - 3.9e-19 68.5 0.0 1e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 EGO57543.1 - 1.1e-16 60.9 14.2 1.1e-16 60.9 14.2 6.1 5 1 1 6 6 6 1 HSA SnAC PF14619.6 EGO57543.1 - 1.7e-13 51.0 0.2 1.7e-13 51.0 0.2 4.3 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 EGO57543.1 - 2.4e-10 40.7 0.1 2.4e-10 40.7 0.1 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit QLQ PF08880.11 EGO57543.1 - 4.7e-09 35.9 4.0 4.7e-09 35.9 4.0 2.2 2 0 0 2 2 2 1 QLQ RBR PF17208.3 EGO57543.1 - 0.0044 17.7 4.2 0.0044 17.7 4.2 3.7 3 1 1 4 4 4 1 RNA binding Region WD40 PF00400.32 EGO57545.1 - 5.4e-15 55.5 8.5 0.002 18.9 0.6 5.6 6 0 0 6 6 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO57545.1 - 7.6e-05 22.9 0.0 1.8 8.9 0.0 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2457 PF10446.9 EGO57545.1 - 0.052 12.7 10.5 0.084 12.0 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 EGO57545.1 - 0.057 13.4 4.1 0.11 12.5 4.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Vfa1 PF08432.10 EGO57545.1 - 0.076 13.3 1.4 0.15 12.4 1.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.6 EGO57545.1 - 0.29 10.8 4.9 0.57 9.8 4.9 1.5 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EGO57545.1 - 0.6 9.4 12.0 0.9 8.8 12.0 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 EGO57545.1 - 1.3 8.7 15.1 0.12 12.1 10.4 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 EGO57545.1 - 1.5 9.2 14.4 3.2 8.2 14.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF5520 PF17658.1 EGO57545.1 - 1.8 7.6 3.8 3.2 6.8 2.8 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5520) DNA_pol_phi PF04931.13 EGO57545.1 - 1.9 6.5 12.9 2.6 6.0 12.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 EGO57545.1 - 2.3 8.6 16.6 0.71 10.3 13.1 1.9 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Astro_capsid_p PF12226.8 EGO57545.1 - 2.5 7.2 6.9 3.8 6.6 6.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RRN3 PF05327.11 EGO57545.1 - 3.3 6.2 5.3 4.5 5.7 5.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 VID27_N PF17748.1 EGO57545.1 - 3.6 7.4 5.1 7.3 6.4 5.1 1.4 1 0 0 1 1 1 0 VID27 N-terminal region Sigma70_ner PF04546.13 EGO57545.1 - 7.3 6.4 12.1 43 3.9 0.1 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region PhyH PF05721.13 EGO57546.1 - 0.00076 19.8 0.1 0.0018 18.6 0.1 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) BCNT PF07572.12 EGO57547.1 - 3.2e-22 78.4 2.9 6.5e-22 77.4 2.9 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development DUF349 PF03993.12 EGO57547.1 - 0.039 14.3 0.2 0.039 14.3 0.2 3.3 4 0 0 4 4 4 0 Domain of Unknown Function (DUF349) G-alpha PF00503.20 EGO57550.1 - 5.4e-125 417.2 1.7 6.2e-125 417.0 1.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGO57550.1 - 2.4e-15 56.4 1.4 2.8e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 EGO57550.1 - 8.4e-05 22.3 0.0 0.00036 20.3 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 EGO57550.1 - 0.002 17.5 3.0 0.11 11.9 0.0 2.7 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 EGO57550.1 - 0.017 14.8 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EGO57550.1 - 0.021 15.0 0.1 2 8.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 EGO57550.1 - 0.034 13.2 0.1 0.08 12.0 0.1 1.6 1 1 0 1 1 1 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 EGO57550.1 - 0.087 12.2 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 EGO57550.1 - 0.13 11.8 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGO57550.1 - 0.14 12.3 0.1 9 6.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DSBA PF01323.20 EGO57551.1 - 5.6e-12 45.8 0.0 2.8e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Serglycin PF04360.12 EGO57551.1 - 0.89 9.5 6.5 2.9 7.8 6.5 1.8 1 0 0 1 1 1 0 Serglycin DUF543 PF04418.12 EGO57552.1 - 3.1e-29 100.8 0.1 3.6e-29 100.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.9 EGO57553.1 - 3.1e-68 229.8 1.3 1.2e-67 227.8 1.3 2.1 1 0 0 1 1 1 1 Urb2/Npa2 family DUF577 PF04510.12 EGO57553.1 - 0.00074 19.5 0.4 0.039 13.9 0.0 3.2 3 0 0 3 3 3 1 Family of unknown function (DUF577) DUF3287 PF11690.8 EGO57553.1 - 0.15 11.8 0.7 1.4 8.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) D123 PF07065.14 EGO57554.1 - 1.7e-112 375.5 0.4 2.4e-112 375.1 0.4 1.2 1 0 0 1 1 1 1 D123 NOA36 PF06524.12 EGO57554.1 - 1.4 8.1 12.0 2.5 7.3 5.9 2.4 2 0 0 2 2 2 0 NOA36 protein cwf21 PF08312.12 EGO57555.1 - 9.5e-18 64.1 14.0 2.6e-17 62.7 14.0 1.8 1 0 0 1 1 1 1 cwf21 domain Trans_reg_C PF00486.28 EGO57555.1 - 0.091 12.9 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal HTH_psq PF05225.16 EGO57556.1 - 0.0088 15.8 2.9 2.8 7.8 0.0 4.5 5 1 1 6 6 6 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 EGO57556.1 - 0.016 15.3 0.4 9.7 6.4 0.1 3.9 4 0 0 4 4 4 0 Helix-turn-helix domain HTH_30 PF13556.6 EGO57556.1 - 0.037 13.8 0.1 52 3.8 0.0 3.9 3 1 1 4 4 4 0 PucR C-terminal helix-turn-helix domain HTH_23 PF13384.6 EGO57556.1 - 0.042 13.7 0.0 3 7.7 0.0 3.3 3 0 0 3 3 3 0 Homeodomain-like domain HTH_11 PF08279.12 EGO57556.1 - 0.084 12.8 0.0 49 4.0 0.0 3.5 3 1 1 4 4 4 0 HTH domain HTH_24 PF13412.6 EGO57556.1 - 0.1 12.2 0.0 15 5.3 0.0 3.1 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding RasGEF PF00617.19 EGO57558.1 - 4.1e-59 199.8 0.2 9.5e-59 198.6 0.2 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGO57558.1 - 2.3e-27 95.3 1.1 5.3e-27 94.1 1.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 EGO57558.1 - 1.6e-15 56.5 0.1 3.5e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGO57558.1 - 5.4e-14 51.8 0.2 1.6e-13 50.3 0.2 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGO57558.1 - 1.9e-13 49.9 0.1 4.2e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 EGO57558.1 - 0.038 14.1 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 WW domain Ser_hydrolase PF06821.13 EGO57558.1 - 0.1 12.4 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Serine hydrolase Fungal_trans PF04082.18 EGO57561.1 - 1.1e-14 54.2 1.1 1.5e-14 53.6 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EGO57561.1 - 6.2e-07 29.6 12.8 7.7e-05 22.9 5.5 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO57561.1 - 0.0062 17.3 12.1 0.82 10.7 1.3 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO57561.1 - 0.039 14.4 16.3 0.31 11.6 4.3 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 EGO57561.1 - 0.053 14.2 0.5 4 8.1 0.1 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 EGO57561.1 - 3.7 7.9 6.9 2.1 8.8 2.8 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Glyco_hydro_16 PF00722.21 EGO57563.1 - 1.1e-14 54.3 0.0 1.9e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_64 PF16483.5 EGO57564.1 - 1.2e-118 396.6 0.6 1.4e-118 396.4 0.6 1.1 1 0 0 1 1 1 1 Beta-1,3-glucanase Alanine_zipper PF11839.8 EGO57565.1 - 1.7 9.1 9.5 3.2 8.2 9.5 1.4 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Imm49 PF15575.6 EGO57566.1 - 0.083 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 49 CLZ PF16526.5 EGO57566.1 - 0.16 12.4 0.4 23 5.4 0.0 2.6 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ndc1_Nup PF09531.10 EGO57566.1 - 0.23 10.1 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Phosphodiest PF01663.22 EGO57567.1 - 3.3e-14 53.3 0.7 6.6e-14 52.3 0.2 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGO57567.1 - 5.2e-05 22.8 0.0 0.00096 18.6 0.0 2.3 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 EGO57567.1 - 0.00033 20.1 0.4 0.00062 19.2 0.4 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 EGO57567.1 - 0.3 11.2 0.8 12 6.0 0.0 2.3 2 0 0 2 2 2 0 PglZ domain PUF PF00806.19 EGO57569.1 - 2e-48 159.4 1.8 4.8e-07 29.1 0.0 8.4 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat DUF3654 PF12376.8 EGO57569.1 - 0.069 13.3 0.3 0.069 13.3 0.3 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF3654) DUF87 PF01935.17 EGO57569.1 - 0.61 10.1 5.9 0.59 10.2 1.0 2.6 2 1 0 2 2 2 0 Helicase HerA, central domain Meth_synt_2 PF01717.18 EGO57570.1 - 2.4e-149 497.0 0.0 6.7e-145 482.4 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EGO57570.1 - 7.4e-122 406.8 0.0 1.1e-115 386.5 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 EGO57570.1 - 0.019 14.2 0.1 3.7 6.6 0.0 2.6 2 1 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) ApoC-I PF04691.12 EGO57570.1 - 0.1 12.5 0.2 1.4 8.9 0.0 2.7 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) SHOCT PF09851.9 EGO57570.1 - 6.5 6.6 8.0 0.61 9.9 0.2 3.0 3 0 0 3 3 3 0 Short C-terminal domain EF-hand_4 PF12763.7 EGO57572.1 - 7.1e-26 90.2 0.0 7.5e-14 51.5 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EGO57572.1 - 5.6e-05 22.4 0.0 0.23 11.1 0.0 2.5 2 0 0 2 2 2 2 EF hand DUF1720 PF08226.11 EGO57572.1 - 0.00011 22.6 131.0 0.00023 21.5 34.0 8.1 5 2 3 8 8 8 4 Domain of unknown function (DUF1720) EF-hand_6 PF13405.6 EGO57572.1 - 0.016 15.1 0.1 6.7 6.9 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain EF-hand_7 PF13499.6 EGO57572.1 - 0.42 11.1 10.0 2 8.9 0.0 3.3 4 0 0 4 4 4 0 EF-hand domain pair PIN_4 PF13638.6 EGO57573.1 - 0.15 12.4 0.0 0.43 10.9 0.0 1.6 2 0 0 2 2 2 0 PIN domain Chlorophyllase2 PF12740.7 EGO57573.1 - 0.24 10.3 0.1 0.27 10.1 0.1 1.0 1 0 0 1 1 1 0 Chlorophyllase enzyme Forkhead PF00250.18 EGO57575.1 - 1.1e-34 118.6 0.2 2.1e-34 117.6 0.2 1.5 1 0 0 1 1 1 1 Forkhead domain ATG101 PF07855.12 EGO57576.1 - 4.6e-50 169.6 0.0 5.6e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 GRP PF07172.11 EGO57576.1 - 3.5 8.4 21.4 2.7 8.8 2.4 2.3 2 0 0 2 2 2 0 Glycine rich protein family TraT PF05818.12 EGO57576.1 - 6.4 6.4 8.6 1.8 8.2 5.6 1.6 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein SelK_SelG PF10961.8 EGO57576.1 - 6.5 7.4 20.2 0.47 11.1 0.3 2.6 3 0 0 3 3 3 0 Selenoprotein SelK_SelG Peroxin-3 PF04882.12 EGO57577.1 - 4.3e-164 547.0 0.0 5.1e-164 546.7 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 DGCR6 PF07324.11 EGO57577.1 - 0.065 12.8 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein Sybindin PF04099.12 EGO57578.1 - 1.7e-22 79.9 0.0 2.4e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Pkinase PF00069.25 EGO57579.1 - 4.1e-60 203.4 0.0 3.7e-55 187.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57579.1 - 6.6e-35 120.6 0.0 6.8e-34 117.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO57579.1 - 2.8e-08 33.4 0.0 9.7e-08 31.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGO57579.1 - 0.00072 19.5 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGO57579.1 - 0.0067 15.3 0.0 0.02 13.7 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGO57581.1 - 5e-50 170.3 0.0 7.5e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57581.1 - 6.2e-28 97.8 0.0 8.5e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGO57581.1 - 0.0072 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGO57581.1 - 0.023 14.0 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EGO57581.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family MaoC_dehydratas PF01575.19 EGO57582.1 - 0.012 15.2 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 MaoC like domain Trypan_PARP PF05887.11 EGO57582.1 - 0.078 13.0 3.8 0.23 11.4 3.8 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Menin PF05053.13 EGO57583.1 - 0.012 14.1 4.0 0.018 13.4 4.0 1.2 1 0 0 1 1 1 0 Menin Pkinase PF00069.25 EGO57584.1 - 6.6e-71 238.8 0.0 1e-70 238.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57584.1 - 1e-50 172.4 0.0 1.8e-50 171.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 EGO57584.1 - 1.5e-27 95.8 0.0 3.4e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 EGO57584.1 - 1.5e-17 63.5 0.2 5.7e-17 61.6 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGO57584.1 - 9.1e-16 58.1 0.0 1.7e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EGO57584.1 - 1.6e-14 54.3 0.0 2.9e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 EGO57584.1 - 3e-07 30.0 0.0 0.00014 21.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.16 EGO57584.1 - 0.0077 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_4 PF18017.1 EGO57584.1 - 0.008 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 EGO57584.1 - 0.02 13.7 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EGO57584.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pput2613-deam PF14427.6 EGO57584.1 - 0.17 11.8 0.1 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Pput_2613-like deaminase SAM_Ste50p PF09235.10 EGO57584.1 - 0.24 11.7 0.4 0.68 10.2 0.4 1.8 1 0 0 1 1 1 0 Ste50p, sterile alpha motif DUF3933 PF13069.6 EGO57585.1 - 0.1 12.5 1.1 0.15 12.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3933) Pep3_Vps18 PF05131.14 EGO57586.1 - 1.5e-48 164.4 0.0 5.5e-48 162.6 0.0 2.0 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EGO57586.1 - 1.6e-11 44.2 2.4 1.2e-08 35.0 0.1 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 EGO57586.1 - 0.00062 19.3 0.3 0.0013 18.3 0.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EGO57586.1 - 0.00072 19.3 0.5 0.0017 18.1 0.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO57586.1 - 0.0016 18.3 1.2 0.0016 18.3 1.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain DUF2175 PF09943.9 EGO57586.1 - 0.0018 18.5 0.9 0.006 16.8 0.0 2.3 3 0 0 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_2 PF13639.6 EGO57586.1 - 0.004 17.4 0.4 0.012 16.0 0.4 1.8 1 0 0 1 1 1 1 Ring finger domain Vps39_2 PF10367.9 EGO57586.1 - 0.0043 17.5 0.0 0.0088 16.5 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.7 EGO57586.1 - 0.091 13.1 0.2 0.25 11.7 0.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGO57586.1 - 0.11 12.3 11.0 0.025 14.3 4.2 2.6 2 0 0 2 2 2 0 RING-like zinc finger TPR_11 PF13414.6 EGO57586.1 - 0.18 11.5 0.6 20 5.0 0.4 4.0 4 0 0 4 4 4 0 TPR repeat zf-RING_UBOX PF13445.6 EGO57586.1 - 0.26 11.3 3.5 0.088 12.8 0.6 1.7 2 0 0 2 2 1 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 EGO57586.1 - 0.75 9.9 6.5 0.13 12.3 2.2 1.9 2 0 0 2 2 2 0 Zinc-finger zf-C3HC4 PF00097.25 EGO57586.1 - 2.4 8.1 5.5 0.34 10.8 0.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pertussis_S1 PF02917.14 EGO57588.1 - 1.5 8.5 7.0 2.4 7.9 7.0 1.2 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 zf-C2H2 PF00096.26 EGO57589.1 - 0.0049 17.2 2.5 0.0049 17.2 2.5 5.2 5 1 0 5 5 5 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 EGO57589.1 - 0.0052 16.5 1.2 0.0052 16.5 1.2 4.5 5 0 0 5 5 5 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 EGO57589.1 - 0.02 15.7 1.8 0.02 15.7 1.8 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGO57589.1 - 0.28 11.7 18.0 4.9 7.8 2.9 4.4 4 0 0 4 4 4 0 Zinc-finger double domain Shugoshin_N PF07558.11 EGO57589.1 - 2 8.3 4.4 3.9 7.4 4.4 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Lyase_1 PF00206.20 EGO57590.1 - 2.4e-26 92.9 0.2 3.6e-26 92.3 0.2 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EGO57590.1 - 5.6e-17 62.1 0.0 2.1e-16 60.2 0.0 2.1 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF4089 PF13318.6 EGO57590.1 - 0.083 13.4 0.0 0.52 10.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4089) Luciferase_N PF05295.11 EGO57590.1 - 0.11 12.6 0.0 2.1 8.4 0.0 2.7 2 0 0 2 2 2 0 Luciferase/LBP N-terminal domain Polysacc_deac_1 PF01522.21 EGO57592.1 - 3.2e-29 101.3 0.0 5.3e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EGO57592.1 - 1.2e-05 25.7 13.7 1.2e-05 25.7 13.7 2.9 3 0 0 3 3 3 2 Chitin recognition protein Aminotran_1_2 PF00155.21 EGO57593.1 - 2.7e-80 270.3 0.0 3.5e-80 269.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGO57593.1 - 0.00024 19.8 0.0 0.0004 19.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGO57593.1 - 0.0013 17.8 0.0 0.0041 16.1 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGO57593.1 - 0.0067 15.8 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SNF2_N PF00176.23 EGO57594.1 - 5e-33 114.3 0.2 1.4e-29 102.9 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO57594.1 - 1.4e-21 76.9 0.0 2.9e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO57594.1 - 9.9e-07 28.9 0.0 7.1e-06 26.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EGO57594.1 - 2.6e-06 27.3 0.0 0.0065 16.2 0.0 2.5 2 0 0 2 2 2 2 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 EGO57594.1 - 7.9e-06 25.3 0.1 1.7e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Herpes_capsid PF06112.11 EGO57594.1 - 0.0058 16.7 1.6 0.0058 16.7 1.6 2.1 2 0 0 2 2 2 1 Gammaherpesvirus capsid protein DUF3390 PF11870.8 EGO57594.1 - 0.017 15.5 0.1 1 9.7 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3390) zf-dskA_traR PF01258.17 EGO57594.1 - 0.21 11.6 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger GSH_synth_ATP PF03917.17 EGO57595.1 - 1.1e-139 465.4 0.0 1.2e-139 465.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EGO57595.1 - 4e-32 110.7 0.0 8.5e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Sec1 PF00995.23 EGO57596.1 - 2.8e-134 449.5 0.0 3.3e-134 449.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_hydro_48 PF02011.15 EGO57596.1 - 0.064 11.8 0.0 0.096 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 48 B12-binding PF02310.19 EGO57596.1 - 0.1 12.6 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 B12 binding domain MMM1 PF10296.9 EGO57597.1 - 2.2e-138 460.9 0.2 7.2e-137 455.9 0.2 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 MBOAT PF03062.19 EGO57598.1 - 1.2e-59 202.5 3.0 2.2e-59 201.6 3.0 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SAT PF16073.5 EGO57598.1 - 0.012 15.3 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis CPBP PF02517.16 EGO57600.1 - 3.7e-13 49.7 13.9 1.3e-12 47.9 13.9 2.2 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease EamA PF00892.20 EGO57601.1 - 2.1e-05 24.7 31.3 0.00031 20.9 8.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family PUF PF00806.19 EGO57602.1 - 2.6e-27 92.9 0.0 3.8e-05 23.1 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EGO57602.1 - 8.2e-14 51.2 0.0 2.1e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2811 PF10929.8 EGO57602.1 - 0.065 13.5 0.0 1.7 9.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2811) RP-C_C PF11800.8 EGO57602.1 - 0.078 13.1 2.9 0.12 12.4 0.9 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region Coilin_N PF15862.5 EGO57602.1 - 3.6 7.4 7.6 6.6 6.5 7.6 1.4 1 0 0 1 1 1 0 Coilin N-terminus DUF1682 PF07946.14 EGO57603.1 - 2.1e-116 388.7 2.7 2.4e-116 388.5 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Big_3 PF07523.12 EGO57603.1 - 0.085 13.2 0.2 2.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Thiamine_BP PF01910.17 EGO57604.1 - 4.4e-32 109.8 2.1 5.2e-32 109.6 2.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Polysacc_deac_1 PF01522.21 EGO57604.1 - 0.024 14.5 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide deacetylase Pkinase PF00069.25 EGO57605.1 - 8.2e-39 133.5 0.0 1.2e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57605.1 - 2.5e-26 92.5 0.0 3.7e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO57605.1 - 0.0096 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGO57605.1 - 0.058 13.3 0.1 3.7 7.4 0.0 2.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family TFIIE-A_C PF11521.8 EGO57605.1 - 0.57 10.5 0.0 0.57 10.5 0.0 2.3 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Ecl1 PF12855.7 EGO57606.1 - 8.6e-35 121.4 16.7 8.6e-35 121.4 16.7 1.9 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins zf-FLZ PF04570.14 EGO57606.1 - 0.33 10.4 6.2 0.6 9.6 5.3 1.9 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 Voldacs PF03517.13 EGO57609.1 - 0.055 13.6 1.3 1.9 8.6 0.1 2.8 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling WD40 PF00400.32 EGO57610.1 - 1e-56 187.6 13.5 3e-09 37.3 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO57610.1 - 5.3e-16 58.7 0.0 0.0043 17.3 0.0 5.0 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 EGO57610.1 - 1.1e-14 54.5 8.3 2e-14 53.6 8.3 1.4 1 0 0 1 1 1 1 Tup N-terminal Ge1_WD40 PF16529.5 EGO57610.1 - 6.2e-08 32.0 0.1 0.44 9.4 0.0 5.0 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGO57610.1 - 6.4e-07 29.0 0.0 0.0045 16.4 0.0 4.7 4 1 1 5 5 5 1 WD40-like domain Nup160 PF11715.8 EGO57610.1 - 0.0014 17.4 0.1 2.9 6.4 0.0 3.4 1 1 3 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 EGO57610.1 - 0.0015 18.4 1.0 12 6.0 0.0 4.6 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Golgin_A5 PF09787.9 EGO57610.1 - 0.0099 15.4 2.1 0.014 14.9 2.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Nbas_N PF15492.6 EGO57610.1 - 0.02 14.2 0.9 17 4.6 0.0 3.4 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Fez1 PF06818.15 EGO57610.1 - 0.027 15.0 0.5 0.044 14.2 0.5 1.2 1 0 0 1 1 1 0 Fez1 Cytochrom_D1 PF02239.16 EGO57610.1 - 0.066 11.7 0.2 0.41 9.1 0.1 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 EGO57610.1 - 0.55 10.0 2.4 15 5.4 0.0 3.3 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature FA_hydroxylase PF04116.13 EGO57612.1 - 1.1e-24 87.3 17.0 1.1e-24 87.3 17.0 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2015 PF09435.10 EGO57613.1 - 3.5e-42 142.8 0.0 4.1e-42 142.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 EGO57614.1 - 9e-37 126.3 0.1 1.2e-36 126.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_C PF02866.18 EGO57615.1 - 1e-46 159.0 0.0 1.4e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EGO57615.1 - 1.7e-44 151.3 0.1 2.5e-44 150.8 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EGO57615.1 - 0.042 12.8 0.0 0.073 12.1 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TRAPP PF04051.16 EGO57616.1 - 3.1e-48 163.2 0.0 3.8e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PorB PF11565.8 EGO57616.1 - 0.046 14.1 0.0 0.083 13.3 0.0 1.3 1 0 0 1 1 1 0 Alpha helical Porin B PINIT PF14324.6 EGO57617.1 - 6.4e-40 136.9 0.1 1.2e-39 136.0 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 EGO57617.1 - 2.2e-22 78.5 4.4 4e-22 77.7 4.4 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 EGO57617.1 - 2.2e-08 33.6 0.8 3.4e-07 29.8 0.0 2.8 2 1 1 3 3 3 1 SAP domain zf-Nse PF11789.8 EGO57617.1 - 9.5e-06 25.3 0.5 2e-05 24.3 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EGO57617.1 - 0.0016 18.6 5.3 0.0026 17.9 5.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Sec23_Sec24 PF04810.15 EGO57617.1 - 0.031 14.3 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-RING_5 PF14634.6 EGO57617.1 - 0.064 13.2 2.9 0.11 12.5 2.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Pellino PF04710.14 EGO57617.1 - 0.066 11.9 0.1 0.095 11.4 0.1 1.1 1 0 0 1 1 1 0 Pellino FYVE_2 PF02318.16 EGO57617.1 - 0.12 12.6 0.2 0.22 11.7 0.2 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_UBOX PF13445.6 EGO57617.1 - 0.19 11.8 3.7 0.2 11.7 0.9 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 EGO57617.1 - 0.2 12.0 3.9 0.36 11.2 3.9 1.4 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 EGO57617.1 - 0.46 10.4 2.2 0.95 9.4 2.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.6 EGO57617.1 - 0.99 9.3 4.6 2 8.3 4.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2423 PF10338.9 EGO57618.1 - 8.3e-20 70.8 2.3 8.3e-20 70.8 2.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Sulfatase PF00884.23 EGO57619.1 - 0.00015 21.2 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Cnd3 PF12719.7 EGO57620.1 - 4.6e-95 318.2 2.9 1.3e-94 316.7 0.4 2.7 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EGO57620.1 - 2.8e-09 37.2 8.1 2.1e-05 24.8 2.2 4.6 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 EGO57620.1 - 7.9e-06 25.7 14.8 0.15 12.4 0.0 7.4 9 0 0 9 9 9 3 HEAT repeat Cnd1 PF12717.7 EGO57620.1 - 0.00021 21.4 3.0 0.31 11.1 0.0 4.7 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 TFIIA PF03153.13 EGO57620.1 - 0.0027 17.7 23.5 0.0027 17.7 23.5 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit HEAT_EZ PF13513.6 EGO57620.1 - 0.7 10.5 10.8 15 6.2 0.1 5.3 5 1 1 6 6 6 0 HEAT-like repeat RRM_1 PF00076.22 EGO57621.1 - 1.4e-59 197.8 0.8 1e-17 63.7 0.0 6.1 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EGO57621.1 - 7.2e-06 25.9 1.8 0.24 11.2 0.0 3.8 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 EGO57621.1 - 0.0076 16.4 0.0 9 6.5 0.0 3.7 3 0 0 3 3 3 1 RNA recognition motif PPP4R2 PF09184.11 EGO57621.1 - 1.7 8.1 35.0 0.13 11.8 23.6 2.5 2 0 0 2 2 2 0 PPP4R2 Mg_trans_NIPA PF05653.14 EGO57622.1 - 2.7e-59 200.7 11.2 7.2e-57 192.7 8.2 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EGO57622.1 - 0.0054 16.9 2.1 0.0054 16.9 2.1 3.7 3 1 0 3 3 3 1 EamA-like transporter family Trp_oprn_chp PF09534.10 EGO57622.1 - 0.0085 15.9 6.4 1.7 8.4 0.4 4.2 3 1 1 4 4 4 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4131 PF13567.6 EGO57622.1 - 0.28 10.8 5.3 0.6 9.7 0.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) LRR19-TM PF15176.6 EGO57622.1 - 0.49 10.4 2.4 0.49 10.4 0.0 2.3 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain DUF485 PF04341.12 EGO57622.1 - 1.9 8.5 4.7 0.87 9.6 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF485 DUF4064 PF13273.6 EGO57622.1 - 2.3 8.5 9.5 4 7.8 0.0 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) TssN PF17555.2 EGO57622.1 - 2.7 7.3 6.1 5 6.4 6.1 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF373 PF04123.13 EGO57622.1 - 5.2 6.4 7.0 15 4.9 7.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF373) WD-3 PF09765.9 EGO57624.1 - 0.094 12.0 0.6 0.22 10.8 0.3 1.7 2 0 0 2 2 2 0 WD-repeat region Bac_thur_toxin PF01338.18 EGO57624.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacillus thuringiensis toxin Tyr-DNA_phospho PF06087.12 EGO57626.1 - 8.5e-61 206.1 0.0 1.1e-60 205.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EGO57626.1 - 0.00093 19.1 0.0 0.042 13.7 0.0 2.3 2 0 0 2 2 2 1 PLD-like domain PNRC PF15365.6 EGO57627.1 - 4.9e-08 32.6 6.3 4.9e-08 32.6 6.3 3.9 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif zf-rbx1 PF12678.7 EGO57628.1 - 5.6e-25 87.4 13.0 8.1e-25 86.9 13.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGO57628.1 - 5.7e-17 61.6 9.9 8.1e-17 61.1 9.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EGO57628.1 - 3.8e-06 27.1 14.3 0.00013 22.2 14.3 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO57628.1 - 5.1e-05 23.0 3.0 5.1e-05 23.0 3.0 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO57628.1 - 0.0016 18.3 11.3 0.026 14.4 11.3 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGO57628.1 - 0.0027 17.4 2.4 0.0027 17.4 2.4 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EGO57628.1 - 0.19 11.6 10.7 0.52 10.2 4.3 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO57628.1 - 0.59 10.2 7.4 2.4 8.3 7.4 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 EGO57628.1 - 0.9 9.8 9.3 4.4 7.6 9.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EGO57628.1 - 1.5 8.5 15.0 0.35 10.5 4.9 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EGO57628.1 - 7.5 6.6 12.5 69 3.5 12.5 2.5 1 1 0 1 1 1 0 zinc-RING finger domain CorA PF01544.18 EGO57629.1 - 5.2e-41 140.9 0.0 7.2e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-Tim10_DDP PF02953.15 EGO57630.1 - 1.6e-19 69.3 1.7 1.9e-19 69.0 1.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_L23eN PF03939.13 EGO57631.1 - 7.4e-26 90.1 11.3 7.4e-26 90.1 11.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EGO57631.1 - 1.7e-14 54.0 0.4 1.7e-14 54.0 0.4 1.9 2 1 0 2 2 2 1 Ribosomal protein L23 DUF3326 PF11805.8 EGO57631.1 - 0.015 14.2 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) Hydrolase_2 PF07486.12 EGO57631.1 - 0.14 13.0 0.1 0.26 12.2 0.1 1.4 1 0 0 1 1 1 0 Cell Wall Hydrolase Bmt2 PF11968.8 EGO57632.1 - 5.1e-97 324.0 0.0 6.5e-97 323.7 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 EGO57632.1 - 0.0013 18.6 0.0 0.01 15.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Hydrolase_like PF13242.6 EGO57635.1 - 0.036 14.1 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase PF00702.26 EGO57635.1 - 0.057 13.7 0.0 0.066 13.5 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EGO57638.1 - 9.3e-56 189.1 0.0 1.5e-55 188.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57638.1 - 9.9e-33 113.5 0.0 1.7e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO57638.1 - 9.7e-14 51.3 0.0 6e-11 42.2 0.0 2.6 2 1 1 3 3 3 2 Kinase-like APH PF01636.23 EGO57638.1 - 0.0044 17.0 0.0 0.0089 16.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGO57638.1 - 0.0058 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Aa_trans PF01490.18 EGO57639.1 - 3.2e-58 197.4 32.3 3.9e-58 197.1 32.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MerC PF03203.14 EGO57639.1 - 0.005 17.3 2.0 0.005 17.3 2.0 3.2 3 1 0 3 3 3 1 MerC mercury resistance protein Iso_dh PF00180.20 EGO57640.1 - 1.6e-132 441.9 0.0 1.8e-132 441.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4451 PF14616.6 EGO57643.1 - 0.0005 20.3 0.0 0.0009 19.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Actin PF00022.19 EGO57646.1 - 7e-30 103.9 0.0 1.6e-19 69.9 0.0 2.5 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 EGO57646.1 - 2.5e-05 23.6 0.6 0.075 12.2 0.0 2.3 2 0 0 2 2 2 2 Putative actin-like family FtsA PF14450.6 EGO57646.1 - 0.0031 17.9 0.0 0.025 15.0 0.0 2.2 2 0 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 EGO57646.1 - 0.06 12.2 0.0 1 8.1 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein CorA PF01544.18 EGO57647.1 - 0.018 14.4 0.0 0.018 14.4 0.0 2.8 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein GT87 PF09594.10 EGO57647.1 - 0.066 12.9 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 87 SelK_SelG PF10961.8 EGO57647.1 - 0.1 13.3 0.6 0.29 11.8 0.6 1.7 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Rdx PF10262.9 EGO57647.1 - 0.16 12.2 0.2 0.98 9.7 0.0 2.2 2 0 0 2 2 2 0 Rdx family DUF5446 PF17522.2 EGO57647.1 - 2.4 8.4 4.6 5 7.4 0.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Pkinase PF00069.25 EGO57648.1 - 1.9e-74 250.4 0.6 4.3e-74 249.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57648.1 - 3.8e-37 128.0 1.1 4.7e-37 127.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO57648.1 - 1.4e-08 34.4 0.0 3.2e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like TFIIA PF03153.13 EGO57648.1 - 0.0023 18.0 38.9 0.0032 17.5 38.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Tim54 PF11711.8 EGO57648.1 - 0.085 11.6 5.4 0.21 10.3 5.3 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF4770 PF15994.5 EGO57648.1 - 0.8 9.9 10.8 2 8.6 10.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) EBP50_C PF09007.11 EGO57648.1 - 7 7.6 18.8 0.55 11.2 7.6 2.5 2 0 0 2 2 2 0 EBP50, C-terminal Lectin_leg-like PF03388.13 EGO57649.1 - 8e-65 218.4 0.0 1.1e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EGO57649.1 - 1.4e-09 38.3 0.1 2e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Bacterial lectin DUF2040 PF09745.9 EGO57650.1 - 2.4e-37 127.7 28.5 2.4e-37 127.7 28.5 4.2 3 2 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) zf-Tim10_DDP PF02953.15 EGO57651.1 - 5.4e-20 70.8 1.1 7e-20 70.4 1.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 EGO57651.1 - 0.0053 16.5 1.4 0.0087 15.7 1.4 1.5 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF3398 PF11878.8 EGO57651.1 - 0.012 16.0 0.4 0.016 15.7 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) PI-PLC-X PF00388.19 EGO57652.1 - 1.8e-70 235.1 0.0 2.8e-70 234.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGO57652.1 - 1.1e-42 145.0 0.0 2e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EGO57652.1 - 0.00018 21.8 0.0 0.00082 19.6 0.0 2.0 2 0 0 2 2 2 1 C2 domain Dehydrin PF00257.19 EGO57652.1 - 0.0069 17.0 4.5 0.0069 17.0 4.5 2.0 2 0 0 2 2 2 1 Dehydrin YL1 PF05764.13 EGO57652.1 - 0.092 12.9 1.0 0.16 12.0 1.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SRP-alpha_N PF04086.13 EGO57652.1 - 0.44 10.4 2.9 0.9 9.4 2.9 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DEAD PF00270.29 EGO57653.1 - 2.6e-31 108.7 0.0 4.5e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO57653.1 - 3.9e-18 65.8 0.1 3.1e-17 62.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO57653.1 - 4.4e-06 26.8 0.0 1.6e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AMPK1_CBM PF16561.5 EGO57654.1 - 0.0033 17.6 0.0 0.0072 16.5 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Iwr1 PF08574.10 EGO57655.1 - 4.1e-14 53.3 12.3 4.1e-14 53.3 12.3 2.9 2 1 0 2 2 2 1 Transcription factor Iwr1 DUF4907 PF16250.5 EGO57655.1 - 0.05 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4907) Pkinase PF00069.25 EGO57656.1 - 1.6e-57 194.9 0.0 2.3e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57656.1 - 3e-20 72.6 0.0 4.7e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO57656.1 - 1.3e-06 27.9 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGO57656.1 - 9.2e-06 25.2 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO57656.1 - 0.00011 22.2 0.3 0.0098 15.8 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGO57656.1 - 0.0042 16.1 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGO57656.1 - 0.0073 15.9 0.2 0.02 14.5 0.2 1.7 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EGO57656.1 - 0.028 13.2 0.0 0.062 12.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase F-box-like PF12937.7 EGO57657.1 - 1.3e-09 37.8 0.3 8.3e-09 35.2 0.1 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EGO57657.1 - 6.7e-08 32.2 0.1 2.2e-07 30.6 0.1 2.0 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 EGO57657.1 - 5.5e-07 29.1 9.4 0.0052 16.7 0.0 6.5 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.7 EGO57657.1 - 2.2e-06 27.9 8.4 0.092 13.2 0.2 6.7 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGO57657.1 - 0.00034 20.7 6.2 0.51 11.1 0.1 6.0 6 0 0 6 6 6 1 Leucine Rich Repeat PRANC PF09372.10 EGO57657.1 - 0.0078 16.5 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 PRANC domain DUF5308 PF17233.2 EGO57657.1 - 0.17 12.1 1.6 0.44 10.8 1.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5308) KH_1 PF00013.29 EGO57658.1 - 5.6e-41 138.2 9.9 7.1e-16 57.8 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EGO57658.1 - 2.5e-10 40.0 8.1 0.005 16.6 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EGO57658.1 - 3.3e-10 39.7 3.9 0.013 15.4 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EGO57658.1 - 0.00031 20.8 6.5 0.45 10.6 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain UAA PF08449.11 EGO57659.1 - 2.8e-44 151.5 8.0 3.7e-44 151.2 8.0 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGO57659.1 - 2.1e-09 37.6 28.5 6.8e-06 26.3 9.0 3.7 2 2 1 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.15 EGO57659.1 - 1.1e-05 24.8 2.1 0.022 13.9 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter CRT-like PF08627.10 EGO57659.1 - 0.0036 16.3 3.7 0.14 11.0 0.2 2.2 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 EGO57659.1 - 0.004 16.6 6.1 0.28 10.5 1.0 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family PsaX PF08078.12 EGO57659.1 - 0.047 13.7 0.6 0.31 11.0 0.1 2.7 2 0 0 2 2 2 0 PsaX family DSPc PF00782.20 EGO57660.1 - 5.1e-25 87.8 0.0 9.1e-23 80.5 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGO57660.1 - 0.0031 17.1 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EGO57660.1 - 0.064 13.6 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTS_2-RNA PF01885.16 EGO57664.1 - 1.8e-62 210.6 0.0 2.2e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family SVIP PF15811.5 EGO57665.1 - 0.38 11.2 10.7 1.2 9.7 10.7 1.9 1 0 0 1 1 1 0 Small VCP/p97-interacting protein TFIIA PF03153.13 EGO57665.1 - 0.85 9.5 27.2 1.2 9.0 12.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit His_Phos_1 PF00300.22 EGO57666.1 - 4.5e-17 62.4 0.0 4.3e-15 55.9 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF5102 PF17104.5 EGO57667.1 - 0.054 13.5 0.3 0.054 13.5 0.3 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5102) RabGAP-TBC PF00566.18 EGO57668.1 - 4.9e-26 91.7 0.2 4.9e-26 91.7 0.2 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PX PF00787.24 EGO57670.1 - 3.9e-19 68.7 0.0 1.5e-18 66.9 0.0 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EGO57670.1 - 9e-13 48.3 11.2 1.3e-07 31.4 0.4 2.1 2 0 0 2 2 2 2 Vps5 C terminal like mRNA_cap_enzyme PF01331.19 EGO57671.1 - 5.4e-51 173.2 0.0 8.6e-51 172.5 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EGO57671.1 - 1.1e-31 109.7 0.0 1.9e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EGO57671.1 - 4.6e-09 36.2 0.0 0.00027 20.6 0.0 2.6 2 1 1 3 3 3 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EGO57671.1 - 0.00015 22.1 0.0 0.00027 21.3 0.0 1.4 1 0 0 1 1 1 1 RNA ligase UPRTase PF14681.6 EGO57672.1 - 3.9e-73 245.3 0.0 4.5e-73 245.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EGO57672.1 - 6.1e-06 25.8 0.0 1.2e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.17 EGO57672.1 - 0.013 14.9 0.1 0.24 10.7 0.1 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase CRCB PF02537.15 EGO57673.1 - 3e-37 126.8 13.1 9.4e-23 80.4 8.7 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) DNA_ligase_A_M PF01068.21 EGO57675.1 - 5.7e-43 146.9 0.0 8.8e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGO57675.1 - 3.4e-41 141.4 0.0 6.6e-41 140.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGO57675.1 - 2.5e-16 60.1 0.5 9.4e-16 58.2 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EGO57675.1 - 3.4e-16 60.0 0.0 7.3e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 RNA ligase BRCT_2 PF16589.5 EGO57675.1 - 9.9e-16 57.9 0.0 2.1e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGO57675.1 - 1.6e-07 31.6 0.0 0.00018 21.8 0.0 3.0 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EGO57675.1 - 0.03 14.6 0.1 3.7 7.9 0.0 3.1 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain DNA_ligase_IV PF11411.8 EGO57675.1 - 0.099 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 DNA ligase IV TSC22 PF01166.18 EGO57675.1 - 0.14 12.5 0.8 0.38 11.1 0.8 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family UPF0560 PF10577.9 EGO57675.1 - 0.16 10.4 0.1 0.23 9.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4449 PF14613.6 EGO57676.1 - 2.6e-67 226.0 0.5 2.6e-67 226.0 0.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Prp18 PF02840.15 EGO57676.1 - 0.03 14.4 3.4 2.1 8.4 0.0 2.7 1 1 1 2 2 2 0 Prp18 domain DUF1841 PF08897.11 EGO57676.1 - 0.042 13.9 1.8 0.057 13.4 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1841) FAP206 PF12018.8 EGO57676.1 - 0.061 12.8 1.5 0.16 11.5 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function Activator-TraM PF11657.8 EGO57676.1 - 0.89 9.4 4.0 1.8 8.4 0.2 2.6 3 0 0 3 3 3 0 Transcriptional activator TraM DOT1 PF08123.13 EGO57677.1 - 2.7e-79 265.5 0.0 4.4e-79 264.8 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 EGO57677.1 - 0.011 16.5 0.0 0.025 15.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGO57677.1 - 0.018 14.8 0.1 0.032 14.0 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain ATG16 PF08614.11 EGO57678.1 - 8.5e-52 176.3 20.7 9.7e-52 176.1 20.7 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 EGO57678.1 - 1.8e-05 24.6 8.7 1.8e-05 24.6 8.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) CCDC144C PF14915.6 EGO57678.1 - 0.0038 16.4 10.3 0.09 11.9 7.2 2.3 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region Spc7 PF08317.11 EGO57678.1 - 0.0048 15.8 8.7 0.0048 15.8 8.7 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein GAS PF13851.6 EGO57678.1 - 0.0062 15.9 12.6 0.016 14.6 9.1 2.2 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 EGO57678.1 - 0.015 15.8 17.7 3.6 8.1 0.1 3.1 2 1 0 2 2 2 0 Apg6 coiled-coil region Pro-rich_19 PF15455.6 EGO57678.1 - 0.027 13.6 1.2 0.038 13.1 1.2 1.3 1 1 0 1 1 1 0 Proline-rich 19 SOGA PF11365.8 EGO57678.1 - 0.032 15.4 12.5 3.9 8.7 1.4 3.1 2 1 1 3 3 3 0 Protein SOGA Lzipper-MIP1 PF14389.6 EGO57678.1 - 0.049 13.9 0.1 0.049 13.9 0.1 2.8 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 AAA_13 PF13166.6 EGO57678.1 - 0.056 12.1 10.0 0.022 13.4 6.1 1.7 1 1 1 2 2 2 0 AAA domain Herpes_UL6 PF01763.16 EGO57678.1 - 0.17 10.4 9.0 0.11 11.0 0.1 2.2 1 1 1 2 2 2 0 Herpesvirus UL6 like DUF4600 PF15372.6 EGO57678.1 - 0.22 11.9 11.0 5.1 7.5 8.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) YabA PF06156.13 EGO57678.1 - 0.31 11.7 11.1 3.3 8.4 3.6 3.0 2 1 1 3 3 3 0 Initiation control protein YabA ZapB PF06005.12 EGO57678.1 - 0.36 11.3 0.1 0.36 11.3 0.1 3.2 2 1 1 3 3 2 0 Cell division protein ZapB BLOC1_2 PF10046.9 EGO57678.1 - 0.37 11.1 8.0 0.89 9.9 4.1 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 betaPIX_CC PF16523.5 EGO57678.1 - 0.45 10.4 0.1 0.45 10.4 0.1 2.9 2 1 1 3 3 3 0 betaPIX coiled coil ABC_tran_CTD PF16326.5 EGO57678.1 - 0.63 10.3 11.3 0.72 10.1 0.0 3.8 3 1 1 4 4 4 0 ABC transporter C-terminal domain Atg14 PF10186.9 EGO57678.1 - 0.77 8.8 14.0 8.1 5.4 14.1 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 EGO57678.1 - 0.97 10.0 8.8 2.5 8.7 6.0 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 CEP63 PF17045.5 EGO57678.1 - 1.1 9.0 14.7 0.083 12.8 6.4 2.5 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa UPF0242 PF06785.11 EGO57678.1 - 1.9 8.6 14.7 0.59 10.2 4.4 2.7 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Cluap1 PF10234.9 EGO57678.1 - 2.9 7.2 13.6 6.6 6.0 13.6 1.7 1 1 0 1 1 1 0 Clusterin-associated protein-1 DUF4200 PF13863.6 EGO57678.1 - 2.9 8.3 13.9 34 4.9 11.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FlgN PF05130.12 EGO57678.1 - 3.8 8.0 17.7 5.2 7.6 12.1 2.5 1 1 1 2 2 2 0 FlgN protein V_ATPase_I PF01496.19 EGO57678.1 - 4 5.2 9.0 0.76 7.6 4.9 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Fez1 PF06818.15 EGO57678.1 - 4.2 7.8 16.1 1.7 9.1 11.4 2.0 1 1 1 2 2 2 0 Fez1 SlyX PF04102.12 EGO57678.1 - 6.9 7.4 12.8 25 5.6 4.3 3.4 2 1 1 3 3 3 0 SlyX Vps16_N PF04841.13 EGO57679.1 - 5.8e-96 321.7 0.0 8.9e-96 321.1 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EGO57679.1 - 2.9e-68 230.3 0.0 5.6e-42 143.9 0.0 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 EGO57679.1 - 0.0031 17.8 0.0 0.43 10.9 0.0 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain FHA PF00498.26 EGO57680.1 - 1.5e-14 54.1 0.0 6.5e-14 52.0 0.0 2.2 2 0 0 2 2 1 1 FHA domain zf-RING_11 PF17123.5 EGO57680.1 - 7.2e-14 51.2 5.3 1.3e-13 50.4 5.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EGO57680.1 - 2.6e-07 30.8 9.2 4.4e-07 30.1 9.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGO57680.1 - 0.0017 18.6 5.0 0.0043 17.3 5.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGO57680.1 - 0.0018 18.1 8.8 0.003 17.4 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.6 EGO57680.1 - 0.0029 17.8 0.9 0.006 16.8 0.9 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-RING_5 PF14634.6 EGO57680.1 - 0.0035 17.3 6.4 0.0057 16.6 6.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGO57680.1 - 0.0068 16.4 1.7 0.013 15.6 1.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Yop-YscD_cpl PF16697.5 EGO57680.1 - 0.0087 16.4 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_2 PF13923.6 EGO57680.1 - 0.0088 15.9 8.2 0.016 15.0 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EGO57680.1 - 0.023 14.6 4.6 0.042 13.7 4.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.6 EGO57680.1 - 0.029 14.5 1.4 0.058 13.6 1.4 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.6 EGO57680.1 - 0.041 13.9 9.1 0.082 12.9 9.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF4888 PF16229.5 EGO57680.1 - 0.054 13.5 0.2 3.7 7.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4888) Cys_rich_CPXG PF14255.6 EGO57680.1 - 0.069 13.1 0.5 0.88 9.5 0.1 2.4 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-C3HC4_4 PF15227.6 EGO57680.1 - 1.1 9.5 6.6 2.4 8.4 6.6 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Peptidase_M16_C PF05193.21 EGO57681.1 - 1.9e-68 230.1 0.0 3.5e-68 229.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGO57681.1 - 9.2e-46 155.5 0.0 1.7e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) EPL1 PF10513.9 EGO57682.1 - 0.47 10.8 16.3 0.35 11.3 7.4 2.7 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF4407 PF14362.6 EGO57682.1 - 5.8 6.2 10.0 9.5 5.5 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) S1 PF00575.23 EGO57683.1 - 3.6e-84 277.1 48.4 3.8e-17 62.4 0.4 13.4 13 0 0 13 13 13 10 S1 RNA binding domain S1_2 PF13509.6 EGO57683.1 - 9.1e-07 28.9 0.4 13 6.0 0.0 5.5 4 0 0 4 4 4 1 S1 domain RNase_II_C_S1 PF18614.1 EGO57683.1 - 1.3e-06 28.2 3.5 0.53 10.3 0.1 6.4 6 0 0 6 6 6 1 RNase II-type exonuclease C-terminal S1 domain TPR_14 PF13428.6 EGO57683.1 - 1.4e-05 25.5 2.6 5.1 8.2 0.1 5.2 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGO57683.1 - 0.00099 19.6 2.6 4.1 8.2 0.1 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGO57683.1 - 0.0059 17.1 1.7 6.5 7.4 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF2187 PF09953.9 EGO57683.1 - 0.072 13.1 0.5 14 5.8 0.1 3.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2187) NRDE-2 PF08424.10 EGO57683.1 - 0.11 11.6 0.1 0.11 11.6 0.1 3.8 2 1 1 3 3 2 0 NRDE-2, necessary for RNA interference TPR_8 PF13181.6 EGO57683.1 - 0.17 12.2 0.3 1 9.8 0.0 2.6 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGO57683.1 - 0.33 11.2 1.3 1.5 9.1 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Suf PF05843.14 EGO57683.1 - 0.68 9.9 19.8 0.25 11.3 2.4 4.3 2 2 1 3 3 3 0 Suppressor of forked protein (Suf) PCB_OB PF17092.5 EGO57683.1 - 8 7.3 25.7 1.6 9.5 0.4 8.4 7 3 2 10 10 10 0 Penicillin-binding protein OB-like domain Grp7_allergen PF16984.5 EGO57686.1 - 0.083 12.9 0.2 0.17 12.0 0.1 1.5 1 1 0 1 1 1 0 Group 7 allergen EF-hand_4 PF12763.7 EGO57688.1 - 4.8e-05 23.3 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand MAP65_ASE1 PF03999.12 EGO57689.1 - 4e-80 270.2 7.9 6.2e-80 269.6 7.6 1.5 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) ISPD_C PF18706.1 EGO57689.1 - 0.011 15.4 0.9 0.019 14.6 0.9 1.3 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain Sipho_Gp157 PF05565.11 EGO57689.1 - 0.32 11.0 7.0 0.42 10.6 0.7 2.8 2 0 0 2 2 2 0 Siphovirus Gp157 Spectrin PF00435.21 EGO57689.1 - 0.53 10.8 17.3 2.1 8.9 0.3 4.3 3 1 1 4 4 4 0 Spectrin repeat CK2S PF15011.6 EGO57689.1 - 1.1 9.1 5.5 4.8 7.0 1.9 3.2 3 0 0 3 3 3 0 Casein Kinase 2 substrate WXG100 PF06013.12 EGO57689.1 - 2.4 8.5 6.8 9.8 6.5 0.0 3.9 3 1 1 4 4 4 0 Proteins of 100 residues with WXG ZapB PF06005.12 EGO57689.1 - 6.7 7.2 19.3 8.5 6.9 0.1 4.5 4 0 0 4 4 4 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 EGO57689.1 - 8 6.7 17.1 9.3 6.5 6.7 4.1 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding GTP_EFTU PF00009.27 EGO57690.1 - 5.9e-60 202.2 0.0 9.2e-60 201.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGO57690.1 - 1.5e-16 60.2 0.0 3.6e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGO57690.1 - 1.5e-09 38.1 0.0 4.4e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGO57690.1 - 8.6e-08 32.2 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EGO57690.1 - 3.3e-05 23.6 0.1 0.00066 19.5 0.0 3.0 3 1 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 EGO57690.1 - 0.026 14.6 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase GldM_C PF12080.8 EGO57690.1 - 0.078 13.2 0.6 0.16 12.2 0.1 1.7 2 0 0 2 2 2 0 GldM C-terminal domain Paf67 PF10255.9 EGO57691.1 - 1.4e-156 521.5 0.1 1.8e-156 521.2 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 EGO57691.1 - 0.031 14.4 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Usp PF00582.26 EGO57693.1 - 7.5e-09 36.2 1.8 5.5e-08 33.4 0.0 2.4 2 0 0 2 2 2 1 Universal stress protein family ABA_GPCR PF12430.8 EGO57694.1 - 3.1e-53 180.2 1.7 6.7e-53 179.1 1.7 1.6 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EGO57694.1 - 1.8e-24 85.6 0.1 1.1e-23 83.1 0.0 2.3 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal SH3_1 PF00018.28 EGO57696.1 - 3.6e-05 23.3 0.0 7.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SeqA_N PF17206.3 EGO57696.1 - 0.02 14.2 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 SeqA protein N-terminal domain SH3_9 PF14604.6 EGO57696.1 - 0.045 13.6 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain PalH PF08733.10 EGO57697.1 - 1.5e-115 385.8 0.0 1.8e-115 385.5 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 TRAM_LAG1_CLN8 PF03798.16 EGO57698.1 - 3.1e-35 121.7 23.1 3.1e-35 121.7 23.1 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EGO57698.1 - 3.9e-27 93.7 0.1 3.9e-27 93.7 0.1 2.0 2 0 0 2 2 2 1 TRAM1-like protein ABC_membrane PF00664.23 EGO57701.1 - 7.1e-37 127.5 7.8 1.6e-36 126.3 7.8 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGO57701.1 - 1e-31 110.2 0.0 2e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGO57701.1 - 0.038 13.9 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 EGO57701.1 - 0.039 14.2 0.2 0.81 10.0 0.2 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGO57701.1 - 0.045 13.5 0.3 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 EGO57701.1 - 0.084 12.5 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.7 EGO57701.1 - 0.13 11.2 0.0 0.45 9.4 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain Epiglycanin_TR PF05647.11 EGO57701.1 - 8.7 6.3 14.0 18 5.3 14.0 1.5 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like EnY2 PF10163.9 EGO57704.1 - 0.00093 19.5 0.0 0.013 15.9 0.0 2.4 2 0 0 2 2 2 1 Transcription factor e(y)2 UBM PF14377.6 EGO57704.1 - 0.0084 15.5 0.2 2.4 7.7 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin binding region AhpC-TSA_2 PF13911.6 EGO57705.1 - 2.6e-09 37.2 0.0 4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EGO57705.1 - 0.0034 17.3 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Zn_clus PF00172.18 EGO57706.1 - 3.2e-06 27.2 8.5 7.4e-06 26.0 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGO57706.1 - 0.00031 19.7 0.3 0.0022 16.9 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain AAA PF00004.29 EGO57707.1 - 2.6e-98 325.6 0.0 1.1e-47 161.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO57707.1 - 3.8e-25 87.4 4.8 9.5e-14 50.9 0.7 2.7 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EGO57707.1 - 1e-18 67.3 0.3 3.8e-18 65.4 0.3 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EGO57707.1 - 1.9e-14 53.7 0.0 3.2e-06 27.0 0.0 3.0 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGO57707.1 - 8.2e-14 52.1 0.0 2.1e-07 31.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGO57707.1 - 1.9e-13 51.2 0.0 0.00018 22.0 0.0 4.4 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EGO57707.1 - 4.3e-12 46.2 0.4 3.5e-06 27.1 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGO57707.1 - 7.5e-12 45.6 0.0 4.7e-05 23.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGO57707.1 - 1.6e-09 38.1 0.3 0.029 14.7 0.0 4.1 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 EGO57707.1 - 2.6e-09 36.8 0.0 0.0012 18.1 0.0 2.8 2 1 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 EGO57707.1 - 5.2e-08 32.6 0.0 1.4e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_25 PF13481.6 EGO57707.1 - 8.1e-08 32.1 3.8 0.2 11.2 0.1 4.9 3 2 1 5 5 5 3 AAA domain AAA_18 PF13238.6 EGO57707.1 - 2e-07 31.6 0.0 0.029 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EGO57707.1 - 2.1e-07 30.5 0.2 0.0069 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGO57707.1 - 2.8e-07 30.5 0.1 0.02 14.7 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein ATPase PF06745.13 EGO57707.1 - 5.3e-07 29.2 0.3 0.25 10.6 0.0 3.7 3 0 0 3 3 3 2 KaiC AAA_14 PF13173.6 EGO57707.1 - 5.5e-07 29.7 0.0 0.0082 16.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGO57707.1 - 5.6e-07 29.9 0.0 0.032 14.6 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_7 PF12775.7 EGO57707.1 - 2.2e-06 27.3 0.0 0.037 13.5 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 EGO57707.1 - 3.2e-06 26.5 0.0 0.011 14.9 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_24 PF13479.6 EGO57707.1 - 4.7e-06 26.5 0.0 0.084 12.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain Vps4_C PF09336.10 EGO57707.1 - 5.4e-06 26.3 0.1 2.1e-05 24.4 0.1 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.17 EGO57707.1 - 9.3e-06 24.9 0.1 0.052 12.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 EGO57707.1 - 1.3e-05 25.2 0.0 0.097 12.5 0.0 3.2 3 0 0 3 3 3 2 Bacterial dnaA protein ABC_tran PF00005.27 EGO57707.1 - 1.7e-05 25.3 0.0 0.28 11.7 0.0 3.6 2 1 0 2 2 2 2 ABC transporter AAA_28 PF13521.6 EGO57707.1 - 1.8e-05 25.0 0.0 0.18 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 EGO57707.1 - 2.1e-05 24.3 0.1 0.24 11.1 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 EGO57707.1 - 7.2e-05 22.8 0.0 0.45 10.5 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 EGO57707.1 - 0.00014 21.9 0.0 0.047 13.7 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.12 EGO57707.1 - 0.00015 21.8 0.1 0.18 11.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.6 EGO57707.1 - 0.0002 21.8 0.0 0.6 10.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain PhoH PF02562.16 EGO57707.1 - 0.00023 20.7 0.3 0.69 9.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 EGO57707.1 - 0.00024 21.0 0.0 0.69 9.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EGO57707.1 - 0.00029 20.7 0.1 0.93 9.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 EGO57707.1 - 0.00046 20.0 0.3 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 EGO57707.1 - 0.00064 19.7 0.0 1.9 8.3 0.0 3.5 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EGO57707.1 - 0.0011 19.3 0.6 5.9 7.2 0.0 3.6 3 1 1 4 4 3 0 AAA domain DUF2075 PF09848.9 EGO57707.1 - 0.0019 17.5 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 EGO57707.1 - 0.0037 16.5 0.0 1.4 8.0 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain Sigma54_activ_2 PF14532.6 EGO57707.1 - 0.0037 17.4 0.0 0.51 10.4 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 EGO57707.1 - 0.0065 16.2 0.0 0.34 10.6 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 EGO57707.1 - 0.0071 16.3 1.3 2.5 8.0 0.0 4.0 5 0 0 5 5 3 1 NTPase KAP_NTPase PF07693.14 EGO57707.1 - 0.01 15.1 0.4 0.87 8.8 0.0 3.2 2 2 1 4 4 4 0 KAP family P-loop domain IPT PF01745.16 EGO57707.1 - 0.013 14.9 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UFD1 PF03152.14 EGO57707.1 - 0.023 14.2 0.0 0.19 11.2 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Zeta_toxin PF06414.12 EGO57707.1 - 0.025 13.9 0.7 8 5.7 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin Zot PF05707.12 EGO57707.1 - 0.048 13.3 0.0 2.4 7.7 0.0 3.1 3 1 0 3 3 2 0 Zonular occludens toxin (Zot) Cytidylate_kin PF02224.18 EGO57707.1 - 0.048 13.4 0.0 10 5.8 0.0 2.9 2 0 0 2 2 2 0 Cytidylate kinase AAA_6 PF12774.7 EGO57707.1 - 0.055 12.4 0.3 7.7 5.4 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region AFG1_ATPase PF03969.16 EGO57707.1 - 0.091 11.6 0.0 11 4.8 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Sec2p PF06428.11 EGO57707.1 - 0.13 12.3 0.7 0.49 10.4 0.7 2.0 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p MMR_HSR1 PF01926.23 EGO57707.1 - 0.3 11.2 1.6 1.3e+02 2.7 0.0 3.9 3 1 0 3 3 3 0 50S ribosome-binding GTPase Forkhead PF00250.18 EGO57708.1 - 9.5e-34 115.5 0.9 3e-33 113.9 0.3 1.9 2 0 0 2 2 2 1 Forkhead domain FHA PF00498.26 EGO57708.1 - 6.8e-09 36.0 0.0 1.6e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGO57708.1 - 0.0014 18.9 0.0 0.0029 17.9 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain CLU PF13236.6 EGO57710.1 - 4.9e-79 265.2 0.0 1.1e-78 264.1 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EGO57710.1 - 7.2e-53 179.2 0.0 7.2e-53 179.2 0.0 2.4 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EGO57710.1 - 1.5e-30 105.3 7.7 2.9e-15 56.3 0.0 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGO57710.1 - 3.2e-26 90.4 3.8 3.9e-07 29.7 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat CLU_N PF15044.6 EGO57710.1 - 7.2e-20 71.1 0.3 3.5e-19 68.9 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_8 PF13181.6 EGO57710.1 - 3.8e-05 23.5 6.9 0.0094 16.1 0.5 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF727 PF05303.12 EGO57710.1 - 0.042 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF727) TPR_2 PF07719.17 EGO57710.1 - 0.048 13.8 12.5 3.3 8.1 0.2 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGO57710.1 - 0.095 13.1 5.0 21 5.8 0.0 4.7 6 0 0 6 6 4 0 Tetratricopeptide repeat DDHD PF02862.17 EGO57710.1 - 0.11 12.6 2.5 0.34 11.0 2.5 1.8 1 0 0 1 1 1 0 DDHD domain ANAPC3 PF12895.7 EGO57710.1 - 0.11 12.7 2.2 11 6.4 0.2 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TERB2 PF15101.6 EGO57710.1 - 0.28 11.2 3.9 0.68 9.9 3.9 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RP-C_C PF11800.8 EGO57710.1 - 2 8.5 6.9 5.8 6.9 6.9 1.8 1 0 0 1 1 1 0 Replication protein C C-terminal region TPR_4 PF07721.14 EGO57710.1 - 3 8.7 10.5 70 4.5 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat CDC45 PF02724.14 EGO57710.1 - 3 6.0 8.7 4.7 5.4 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Borrelia_P83 PF05262.11 EGO57710.1 - 3.7 5.9 17.7 7.3 5.0 17.7 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein NPR3 PF03666.13 EGO57710.1 - 7.6 5.2 10.4 15 4.2 10.4 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PBP1_TM PF14812.6 EGO57711.1 - 0.022 15.1 13.4 0.06 13.7 4.6 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1993 PF09351.10 EGO57711.1 - 0.045 13.9 0.0 0.45 10.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) RXT2_N PF08595.11 EGO57711.1 - 3.5 7.7 13.2 7.2 6.6 4.3 3.1 3 0 0 3 3 3 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 EGO57711.1 - 4.9 7.6 21.9 3.3 8.2 11.6 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ferric_reduct PF01794.19 EGO57713.1 - 5.5e-23 81.4 9.5 5.5e-23 81.4 9.5 2.0 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGO57713.1 - 8.5e-20 71.4 0.0 9.4e-11 42.1 0.0 2.5 2 1 1 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGO57713.1 - 4.3e-11 42.9 0.0 6.9e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain FtsX PF02687.21 EGO57713.1 - 1 9.9 5.4 10 6.7 0.2 3.1 2 2 1 3 3 3 0 FtsX-like permease family Yippee-Mis18 PF03226.14 EGO57714.1 - 8.3e-16 58.1 0.1 1.6e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EGO57714.1 - 0.0017 18.6 0.3 0.0037 17.5 0.3 1.5 1 0 0 1 1 1 1 C-terminal domain of RIG-I Zn_ribbon_SprT PF17283.2 EGO57714.1 - 0.04 13.8 0.4 3.8 7.5 0.0 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain RNA_POL_M_15KD PF02150.16 EGO57714.1 - 0.089 12.7 0.9 15 5.6 0.1 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Pox_A12 PF04651.13 EGO57714.1 - 0.36 10.9 4.3 0.52 10.4 4.3 1.1 1 0 0 1 1 1 0 Poxvirus A12 protein Red1 PF07964.11 EGO57714.1 - 1.3 7.2 7.6 1.7 6.8 7.6 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Presenilin PF01080.17 EGO57714.1 - 7.4 5.2 6.7 8.6 5.0 6.7 1.1 1 0 0 1 1 1 0 Presenilin Nuc_sug_transp PF04142.15 EGO57715.1 - 1.3e-09 37.7 0.4 1.9e-09 37.2 0.4 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EGO57715.1 - 8.6e-09 35.7 23.8 0.00032 20.9 4.7 2.8 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EGO57715.1 - 0.00024 20.5 0.7 0.00024 20.5 0.7 1.7 2 0 0 2 2 2 1 Triose-phosphate Transporter family PUNUT PF16913.5 EGO57715.1 - 0.09 12.0 7.7 0.024 13.9 4.5 1.6 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport DUF423 PF04241.15 EGO57715.1 - 0.79 10.0 6.8 5.1 7.4 0.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF423) PDR_assoc PF08370.11 EGO57715.1 - 4 7.3 9.8 1.1 9.1 0.9 3.1 3 0 0 3 3 3 0 Plant PDR ABC transporter associated DUF2985 PF11204.8 EGO57716.1 - 5.1e-36 122.7 1.4 5.1e-36 122.7 1.4 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2985) Sen15 PF09631.10 EGO57717.1 - 3.1e-25 88.4 0.1 6.3e-25 87.4 0.0 1.6 2 0 0 2 2 2 1 Sen15 protein ADH_N PF08240.12 EGO57718.1 - 3.7e-28 97.6 0.3 6.5e-28 96.8 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO57718.1 - 2.3e-15 56.7 0.0 4.3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EGO57718.1 - 2.4e-05 24.1 0.4 8.6e-05 22.4 0.4 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 EGO57718.1 - 0.00029 20.4 0.1 0.00068 19.2 0.1 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGO57718.1 - 0.057 14.5 0.0 0.16 13.0 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGO57718.1 - 0.075 12.3 0.2 0.12 11.6 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Zip PF02535.22 EGO57719.1 - 4e-23 82.2 5.7 3.4e-20 72.5 2.0 2.0 2 0 0 2 2 2 2 ZIP Zinc transporter DUF5518 PF17647.1 EGO57719.1 - 3.8 7.7 11.9 0.2 11.8 5.2 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5518) Endonuclease_NS PF01223.23 EGO57720.1 - 5.2e-70 235.8 0.0 6.5e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Tmemb_170 PF10190.9 EGO57723.1 - 7.1e-31 106.7 7.9 8.3e-31 106.5 7.9 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 MBOAT PF03062.19 EGO57724.1 - 2.2e-20 73.3 11.5 2.2e-20 73.3 11.5 2.0 3 0 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EGO57724.1 - 0.00012 22.2 2.7 0.00036 20.8 2.7 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family CF222 PF15661.5 EGO57724.1 - 0.02 13.8 1.9 0.034 13.1 1.9 1.3 1 0 0 1 1 1 0 C6orf222, uncharacterised family Orf78 PF06024.12 EGO57724.1 - 0.12 12.7 0.1 0.46 10.8 0.1 2.0 2 0 0 2 2 2 0 Orf78 (ac78) WD40 PF00400.32 EGO57726.1 - 1.6e-30 104.7 27.7 4.2e-06 27.4 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO57726.1 - 2e-11 44.0 0.0 1.9 8.8 0.0 6.0 2 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO57726.1 - 0.074 12.0 0.2 17 4.2 0.1 3.3 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGO57726.1 - 0.094 12.6 0.0 11 5.9 0.0 2.7 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 EGO57726.1 - 0.19 10.5 0.0 0.33 9.6 0.0 1.4 1 0 0 1 1 1 0 Nup133 N terminal like Frtz PF11768.8 EGO57726.1 - 0.33 9.2 0.0 0.51 8.6 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz zf-C2H2 PF00096.26 EGO57727.1 - 1.4e-28 97.7 38.9 0.0004 20.7 0.2 9.6 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO57727.1 - 1.6e-18 65.8 44.0 0.018 15.9 0.1 10.0 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGO57727.1 - 4.9e-14 52.0 44.7 5.5e-05 23.4 0.8 9.7 10 0 0 10 10 10 4 Zinc-finger double domain zf-C2H2_aberr PF17017.5 EGO57727.1 - 1.4e-06 28.6 15.3 0.078 13.1 2.2 4.8 3 2 2 5 5 5 3 Aberrant zinc-finger zf-C2H2_8 PF15909.5 EGO57727.1 - 4.6e-06 26.8 16.0 0.0065 16.8 2.1 4.3 2 2 2 4 4 4 2 C2H2-type zinc ribbon FOXP-CC PF16159.5 EGO57727.1 - 8.3e-05 23.1 28.6 0.013 16.2 0.2 8.0 6 1 3 9 9 9 1 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 EGO57727.1 - 0.00071 19.8 26.3 1.6 9.1 0.7 8.5 9 0 0 9 9 9 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EGO57727.1 - 0.0074 16.6 2.6 0.0074 16.6 2.6 7.0 5 2 3 8 8 8 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 EGO57727.1 - 0.012 16.0 17.2 0.99 9.9 0.1 6.5 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf_ZIC PF18366.1 EGO57727.1 - 0.28 11.3 3.9 8.4 6.6 0.2 4.9 6 0 0 6 6 6 0 Zic proteins zinc finger domain zf-C2H2_3rep PF18868.1 EGO57727.1 - 0.99 10.1 14.7 2 9.1 1.1 4.7 2 2 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats Ogr_Delta PF04606.12 EGO57727.1 - 4.4 7.4 6.3 2.1 8.4 0.4 3.4 3 1 0 3 3 3 0 Ogr/Delta-like zinc finger RNA_pol_Rpb6 PF01192.22 EGO57728.1 - 1.4e-17 63.3 0.1 2.4e-17 62.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.12 EGO57728.1 - 0.077 13.0 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit WSC PF01822.19 EGO57729.1 - 5.3e-37 125.9 25.9 2.4e-20 72.5 11.9 4.7 4 2 0 4 4 4 2 WSC domain PCI PF01399.27 EGO57730.1 - 1.7e-07 31.7 0.1 1.7e-07 31.7 0.1 3.0 3 0 0 3 3 3 1 PCI domain G-gamma PF00631.22 EGO57731.1 - 5.3e-27 93.6 0.1 6.7e-27 93.3 0.1 1.1 1 0 0 1 1 1 1 GGL domain Ribosomal_L11 PF00298.19 EGO57731.1 - 0.093 13.2 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain Rdx PF10262.9 EGO57732.1 - 1.1e-33 115.2 0.0 2.6e-33 114.0 0.0 1.7 1 0 0 1 1 1 1 Rdx family Sin_N PF04801.13 EGO57732.1 - 0.00022 20.6 8.7 0.00029 20.2 8.7 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region Roughex PF06020.11 EGO57732.1 - 0.0063 15.7 4.5 0.0085 15.2 4.5 1.1 1 0 0 1 1 1 1 Drosophila roughex protein Spt20 PF12090.8 EGO57732.1 - 0.038 13.6 14.9 0.053 13.1 14.9 1.3 1 0 0 1 1 1 0 Spt20 family DUF908 PF06012.12 EGO57732.1 - 0.04 13.3 4.2 0.046 13.1 4.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PBP_sp32 PF07222.12 EGO57732.1 - 0.069 12.6 9.2 0.13 11.7 9.2 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Hid1 PF12722.7 EGO57732.1 - 1.2 7.2 5.1 1.1 7.3 5.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 EGO57732.1 - 1.3 8.8 8.1 2 8.2 8.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ATP-synt_E PF05680.12 EGO57732.1 - 1.5 9.2 7.3 2.6 8.4 7.3 1.4 1 0 0 1 1 1 0 ATP synthase E chain Presenilin PF01080.17 EGO57732.1 - 3 6.5 8.5 3.3 6.4 8.5 1.1 1 0 0 1 1 1 0 Presenilin Metallophos PF00149.28 EGO57733.1 - 3.5e-40 138.7 0.1 4.5e-40 138.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGO57733.1 - 3e-23 82.0 1.8 4.3e-23 81.5 1.0 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain zf-HC5HC2H_2 PF13832.6 EGO57734.1 - 1.3e-33 115.4 6.6 1.3e-33 115.4 6.6 2.8 3 0 0 3 3 3 1 PHD-zinc-finger like domain EPL1 PF10513.9 EGO57734.1 - 1.2e-32 113.4 0.5 1.2e-32 113.4 0.5 2.5 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 EGO57734.1 - 3.3e-27 94.6 6.4 3.3e-27 94.6 6.4 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EGO57734.1 - 3.5e-14 52.0 1.9 3.5e-14 52.0 1.9 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EGO57734.1 - 1.7e-09 37.4 23.2 1.3e-08 34.6 9.5 2.8 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 EGO57734.1 - 1.2 8.8 11.8 0.018 14.7 1.6 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain LRR_8 PF13855.6 EGO57736.1 - 1.2e-15 57.0 2.9 6.5e-08 32.2 2.3 3.2 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EGO57736.1 - 3.7e-15 55.8 2.7 0.00013 22.3 0.9 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGO57736.1 - 8.7e-06 25.6 5.6 2.6 8.9 0.0 6.2 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_9 PF14580.6 EGO57736.1 - 0.0021 17.6 1.9 0.096 12.2 0.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 EGO57736.1 - 0.017 15.2 9.0 0.57 10.4 0.0 5.1 5 0 0 5 5 5 0 Leucine Rich repeat Biotin_lipoyl PF00364.22 EGO57740.1 - 2.4e-21 75.3 0.7 5e-21 74.3 0.7 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EGO57740.1 - 5.9e-10 39.3 0.4 2.2e-09 37.5 0.2 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EGO57740.1 - 2.3e-05 24.1 0.0 0.0002 21.1 0.0 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like QRPTase_N PF02749.16 EGO57740.1 - 0.15 12.1 0.0 0.71 10.0 0.0 2.0 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain CoA_transf_3 PF02515.17 EGO57742.1 - 1.3e-41 142.9 0.0 6.7e-37 127.5 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Fungal_trans PF04082.18 EGO57744.1 - 1.9e-28 99.3 0.1 2.9e-28 98.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dioxygenase_C PF00775.21 EGO57745.1 - 5e-45 153.2 0.0 7.1e-45 152.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EGO57745.1 - 1.3e-22 79.4 0.3 1.8e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EGO57745.1 - 7e-06 26.2 0.0 2.3e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 EGO57745.1 - 0.087 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 SdrD B-like domain DUF4198 PF10670.9 EGO57745.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) OPT PF03169.15 EGO57747.1 - 1.1e-167 559.5 47.7 7.6e-87 292.4 20.3 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Form-deh_trans PF09163.11 EGO57747.1 - 0.084 12.7 3.1 0.11 12.3 0.7 2.6 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Tetraspanin PF00335.20 EGO57747.1 - 0.86 9.3 3.7 1.7 8.3 0.8 2.6 2 0 0 2 2 2 0 Tetraspanin family DUF3270 PF11674.8 EGO57747.1 - 1.8 8.8 8.4 0.38 10.9 2.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) ketoacyl-synt PF00109.26 EGO57748.1 - 4.4e-61 206.7 1.0 5.9e-61 206.2 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGO57748.1 - 2.4e-34 117.9 2.0 4.2e-34 117.1 1.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGO57748.1 - 0.0003 20.2 0.1 0.0014 18.0 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 EGO57748.1 - 0.15 12.5 0.2 0.4 11.1 0.1 1.8 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension Thiolase_C PF02803.18 EGO57748.1 - 0.26 11.0 2.5 1.7 8.3 0.4 3.1 3 1 0 3 3 3 0 Thiolase, C-terminal domain Ubiq_cyt_C_chap PF03981.12 EGO57749.1 - 2e-39 134.9 2.1 3.1e-39 134.3 2.1 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Codanin-1_C PF15296.6 EGO57749.1 - 1 9.5 3.7 1.1 9.3 0.2 2.6 2 1 0 2 2 2 0 Codanin-1 C-terminus DHFR_1 PF00186.19 EGO57750.1 - 1.5e-22 80.0 0.0 4.7e-22 78.4 0.0 1.8 1 1 0 1 1 1 1 Dihydrofolate reductase TPR_2 PF07719.17 EGO57750.1 - 9.5e-11 41.0 10.2 0.12 12.6 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGO57750.1 - 4.6e-07 30.1 12.4 0.83 10.6 0.2 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGO57750.1 - 1.9e-05 24.3 10.9 0.56 10.1 0.0 5.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO57750.1 - 2.3e-05 24.2 4.6 1.2 9.5 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGO57750.1 - 0.00019 21.6 4.2 0.021 15.2 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO57750.1 - 0.00053 20.4 7.9 0.035 14.6 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO57750.1 - 0.009 16.0 2.9 28 5.1 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 EGO57750.1 - 0.012 15.6 1.5 1.2 9.2 0.1 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TPR_9 PF13371.6 EGO57750.1 - 0.022 14.9 3.7 6.6 7.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGO57750.1 - 0.044 14.1 9.0 38 4.7 0.2 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGO57750.1 - 0.17 12.6 7.2 24 5.7 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO57750.1 - 6.2 7.7 7.5 7 7.5 0.2 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat RIX1 PF08167.12 EGO57751.1 - 5.6e-58 195.8 0.2 1.1e-57 194.9 0.2 1.5 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis YL1 PF05764.13 EGO57751.1 - 0.0023 18.1 5.1 0.0023 18.1 5.1 2.2 2 0 0 2 2 2 1 YL1 nuclear protein Raptor_N PF14538.6 EGO57751.1 - 0.0029 17.5 0.0 0.0069 16.4 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Glyco_hydro_16 PF00722.21 EGO57753.1 - 4.5e-11 42.5 1.6 9e-11 41.6 1.6 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_hydro_45 PF02015.16 EGO57755.1 - 0.054 13.4 0.2 0.057 13.3 0.2 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 45 DUF5109 PF17134.4 EGO57755.1 - 0.1 12.5 0.3 0.25 11.2 0.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5109) Paramyx_P_V_C PF03210.13 EGO57756.1 - 0.087 12.6 1.7 7.2 6.4 0.2 2.7 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal DUF3412 PF11892.8 EGO57756.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3412) Dus PF01207.17 EGO57758.1 - 2.2e-56 191.3 0.0 4.1e-56 190.4 0.0 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Sporozoite_P67 PF05642.11 EGO57758.1 - 0.0036 15.5 4.5 0.0063 14.7 4.5 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Dicty_REP PF05086.12 EGO57758.1 - 0.011 13.7 9.2 0.021 12.9 9.2 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SOG2 PF10428.9 EGO57758.1 - 0.012 14.9 9.6 0.024 13.8 9.6 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein CTNNB1_binding PF08347.11 EGO57758.1 - 0.23 11.6 1.9 0.52 10.5 1.9 1.5 1 0 0 1 1 1 0 N-terminal CTNNB1 binding FSA_C PF10479.9 EGO57758.1 - 0.47 8.5 15.8 0.92 7.6 15.8 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus TMEM154 PF15102.6 EGO57758.1 - 3.3 7.6 16.4 9.6 6.1 16.4 1.8 1 0 0 1 1 1 0 TMEM154 protein family Shisa PF13908.6 EGO57758.1 - 3.8 7.7 8.6 11 6.3 8.6 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Apt1 PF10351.9 EGO57758.1 - 6.2 5.5 8.5 1.4 7.7 5.1 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain MA3 PF02847.17 EGO57759.1 - 5.9e-25 87.5 0.1 1e-24 86.7 0.1 1.4 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 EGO57759.1 - 2.1e-09 37.3 0.7 4.1e-09 36.4 0.7 1.5 1 0 0 1 1 1 1 MIF4G domain FAM176 PF14851.6 EGO57759.1 - 1.4 8.6 4.9 3.5 7.3 4.9 1.6 1 0 0 1 1 1 0 FAM176 family DPM2 PF07297.12 EGO57760.1 - 1.2e-34 118.4 1.3 1.4e-34 118.2 1.3 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EGO57760.1 - 1.5e-05 24.9 0.4 1.7e-05 24.7 0.4 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 EGO57760.1 - 0.00016 21.7 6.3 0.001 19.1 6.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4229) COX14 PF14880.6 EGO57760.1 - 0.0031 17.3 2.9 0.017 14.9 0.0 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c assembly Cytochrom_C_asm PF01578.20 EGO57760.1 - 0.007 16.1 0.3 0.007 16.1 0.3 1.0 1 0 0 1 1 1 1 Cytochrome C assembly protein ING PF12998.7 EGO57764.1 - 0.0013 19.3 0.0 0.0075 16.8 0.0 2.4 1 1 1 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EGO57764.1 - 0.0024 17.8 2.3 0.0024 17.8 2.3 2.3 2 0 0 2 2 2 1 PHD-finger RXLR PF16810.5 EGO57764.1 - 2.9 8.3 5.8 12 6.4 5.8 2.0 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity FapA PF03961.13 EGO57765.1 - 3.7e-06 25.8 0.9 4.4e-06 25.6 0.9 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A Bactofilin PF04519.13 EGO57765.1 - 3.8e-06 27.1 0.7 3.7e-05 23.9 0.5 2.2 1 1 1 2 2 2 1 Polymer-forming cytoskeletal MinC_C PF03775.16 EGO57765.1 - 0.011 15.7 1.1 0.69 9.9 0.0 2.9 2 1 1 3 3 3 0 Septum formation inhibitor MinC, C-terminal domain Fil_haemagg_2 PF13332.6 EGO57765.1 - 0.1 12.7 5.8 0.2 11.8 3.9 2.2 1 1 1 2 2 2 0 Hemagglutinin repeat zf-C2H2 PF00096.26 EGO57767.1 - 0.014 15.9 3.3 0.043 14.3 3.3 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGO57767.1 - 0.21 12.1 1.0 10 6.8 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO57767.1 - 1.9 9.5 3.9 7.1 7.8 3.9 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3602 PF12223.8 EGO57768.1 - 7.6e-11 42.5 13.2 0.0023 18.5 2.6 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DUF4551 PF15087.6 EGO57768.1 - 0.24 10.2 0.9 0.27 10.0 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) HABP4_PAI-RBP1 PF04774.15 EGO57768.1 - 1.1 10.1 7.5 2.3 9.1 6.5 2.0 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family GTP1_OBG PF01018.22 EGO57768.1 - 3.3 7.3 9.1 2.4 7.7 0.6 2.9 1 1 1 3 3 3 0 GTP1/OBG DnaJ PF00226.31 EGO57769.1 - 1e-05 25.6 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 EGO57769.1 - 1e-05 25.5 0.0 1.1e-05 25.4 0.0 1.3 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.6 EGO57769.1 - 0.0018 17.8 2.6 0.0024 17.4 0.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3918) DUF4538 PF15061.6 EGO57769.1 - 0.2 11.4 0.1 0.42 10.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) RNase_H_2 PF13482.6 EGO57770.1 - 0.016 15.2 0.1 0.29 11.1 0.0 2.5 2 0 0 2 2 2 0 RNase_H superfamily Ku PF02735.16 EGO57771.1 - 7.3e-37 127.0 0.0 1.5e-36 126.0 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 EGO57771.1 - 2.3e-36 124.6 0.0 6.5e-36 123.1 0.0 1.8 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 EGO57771.1 - 2.9e-17 63.1 0.1 4.5e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 EGO57771.1 - 0.00028 21.2 0.1 0.00058 20.2 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_C PF03730.14 EGO57771.1 - 0.0052 17.5 0.2 0.054 14.2 0.0 2.6 1 1 1 2 2 2 1 Ku70/Ku80 C-terminal arm Sigma70_r1_1 PF03979.14 EGO57771.1 - 0.14 12.2 1.8 0.57 10.3 1.8 2.0 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Memo PF01875.17 EGO57771.1 - 0.16 11.1 0.1 0.28 10.3 0.1 1.3 1 0 0 1 1 1 0 Memo-like protein DUF4149 PF13664.6 EGO57772.1 - 1.1e-25 89.9 1.3 1.1e-25 89.9 1.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) FliD_N PF02465.18 EGO57773.1 - 0.066 13.9 0.8 0.11 13.2 0.8 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF1295 PF06966.12 EGO57774.1 - 2.2e-41 141.9 9.1 2.6e-41 141.7 9.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Topoisom_bac PF01131.20 EGO57775.1 - 5.1e-106 355.1 0.0 4.2e-100 335.7 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 EGO57775.1 - 5.1e-21 74.8 0.0 9.9e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain TANGO2 PF05742.12 EGO57776.1 - 0.17 11.9 0.1 0.21 11.6 0.1 1.1 1 0 0 1 1 1 0 Transport and Golgi organisation 2 Stb3 PF10330.9 EGO57777.1 - 5.9e-37 125.6 0.0 1e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein SelP_N PF04592.14 EGO57777.1 - 0.83 9.0 7.6 1.7 8.0 7.6 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region C1_2 PF03107.16 EGO57780.1 - 1.2 9.5 10.6 2.1 8.7 10.6 1.4 1 0 0 1 1 1 0 C1 domain Glyco_hydro_76 PF03663.14 EGO57781.1 - 2.1e-51 175.6 9.7 2.6e-51 175.3 9.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EGO57781.1 - 7.8e-08 31.8 1.5 0.032 13.3 0.0 3.0 1 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 EGO57781.1 - 0.00047 18.8 0.2 0.027 13.0 0.0 2.5 1 1 1 3 3 3 2 Beta-L-arabinofuranosidase, GH127 C5-epim_C PF06662.13 EGO57781.1 - 0.0015 18.1 1.3 15 5.0 0.0 3.9 2 1 2 4 4 4 3 D-glucuronyl C5-epimerase C-terminus Glucosamine_iso PF01182.20 EGO57783.1 - 8.6e-71 238.4 0.0 9.7e-71 238.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hydrolase_6 PF13344.6 EGO57784.1 - 5.7e-29 100.2 0.0 8.5e-29 99.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO57784.1 - 4.3e-15 55.5 0.0 1.3e-14 53.9 0.1 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EGO57784.1 - 6.2e-12 46.3 0.0 1.4e-09 38.6 0.0 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGO57784.1 - 2.7e-05 24.3 0.2 0.03 14.4 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase SET PF00856.28 EGO57785.1 - 5.8e-10 39.8 0.0 2.3e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGO57785.1 - 0.024 14.7 5.1 0.024 14.7 5.1 2.1 2 0 0 2 2 2 0 MYND finger HypA PF01155.19 EGO57785.1 - 8.8 6.4 6.9 0.47 10.5 1.3 1.8 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2 PF00096.26 EGO57786.1 - 8.7e-06 25.9 20.8 0.00016 21.9 6.3 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO57786.1 - 0.00054 20.6 4.6 0.00054 20.6 4.6 4.2 4 0 0 4 4 4 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGO57786.1 - 0.0039 17.6 6.6 0.0039 17.6 6.6 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EGO57786.1 - 0.067 13.2 7.9 0.28 11.2 3.7 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 EGO57786.1 - 0.088 13.5 0.5 0.088 13.5 0.5 3.7 3 1 2 5 5 5 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 EGO57786.1 - 0.13 12.6 5.9 0.32 11.3 5.6 1.9 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-met PF12874.7 EGO57786.1 - 1.3 9.6 3.7 7.4 7.1 2.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF629 PF04780.12 EGO57786.1 - 4.8 5.6 7.2 0.56 8.7 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zinc_ribbon_16 PF17034.5 EGO57788.1 - 1.9e-13 50.7 11.1 3.2e-10 40.3 1.9 2.8 3 0 0 3 3 3 2 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 EGO57788.1 - 5.6e-05 22.7 2.2 5.6e-05 22.7 2.2 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type PRIMA1 PF16101.5 EGO57788.1 - 0.12 12.5 4.9 0.28 11.2 4.9 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-RING_2 PF13639.6 EGO57788.1 - 2 8.8 11.5 0.42 11.0 3.8 3.0 3 0 0 3 3 3 0 Ring finger domain Totivirus_coat PF05518.11 EGO57788.1 - 3.2 5.7 10.7 4.8 5.1 10.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein TFIIA PF03153.13 EGO57788.1 - 9.1 6.1 6.1 15 5.5 6.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Efg1 PF10153.9 EGO57789.1 - 1.4e-35 122.1 11.4 1.4e-35 122.1 11.4 2.4 3 0 0 3 3 3 1 rRNA-processing protein Efg1 MutS_III PF05192.18 EGO57789.1 - 0.0054 17.0 2.5 0.0073 16.6 2.5 1.3 1 0 0 1 1 1 1 MutS domain III Arena_ncap_C PF17290.2 EGO57789.1 - 0.045 13.1 0.1 0.084 12.2 0.1 1.4 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain TPR_1 PF00515.28 EGO57791.1 - 2.1e-27 93.8 31.4 0.00063 19.5 0.0 11.8 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGO57791.1 - 4e-27 92.1 34.2 0.004 17.2 0.3 12.2 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 EGO57791.1 - 8.9e-19 66.1 31.4 0.004 17.3 0.0 12.1 13 0 0 13 13 11 7 Tetratricopeptide repeat TPR_12 PF13424.6 EGO57791.1 - 1.1e-15 57.7 27.5 0.0016 18.7 0.1 10.2 8 3 1 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 EGO57791.1 - 4.5e-12 46.3 36.6 0.0026 18.2 0.2 10.1 9 3 2 11 11 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 EGO57791.1 - 9.6e-12 44.1 27.8 0.029 14.4 0.0 10.2 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGO57791.1 - 3.9e-11 42.8 40.4 0.02 15.7 0.0 12.4 12 2 2 14 14 11 4 Tetratricopeptide repeat TPR_6 PF13174.6 EGO57791.1 - 1.4e-09 38.0 25.7 0.014 16.0 0.0 10.3 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGO57791.1 - 1.4e-09 38.5 41.7 0.00045 20.8 2.4 9.0 9 1 1 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGO57791.1 - 8e-07 28.6 27.1 0.039 13.6 0.1 8.8 8 1 1 9 9 9 4 TPR repeat TPR_10 PF13374.6 EGO57791.1 - 3.5e-06 26.7 30.9 0.18 11.7 0.0 10.6 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGO57791.1 - 0.00016 21.8 21.4 0.15 12.5 0.1 9.8 13 0 0 13 13 10 1 Tetratricopeptide repeat TPR_4 PF07721.14 EGO57791.1 - 0.013 16.0 0.2 14 6.6 0.2 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGO57791.1 - 0.016 15.3 1.2 4 7.6 0.1 3.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 EGO57791.1 - 5.2 7.4 17.8 1.1 9.5 0.3 6.1 8 0 0 8 8 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Homeobox_KN PF05920.11 EGO57793.1 - 4.4e-20 71.3 3.1 3.9e-19 68.3 0.8 2.5 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 EGO57793.1 - 3.4e-06 26.8 0.8 6.6e-06 25.9 0.8 1.5 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 EGO57795.1 - 1.1e-08 34.8 0.3 8.1e-08 32.0 0.0 2.4 2 0 0 2 2 2 1 Homeodomain Rhodanese PF00581.20 EGO57795.1 - 4.9e-05 23.8 0.0 0.00015 22.2 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain PIG-X PF08320.12 EGO57796.1 - 3.2e-70 236.3 0.0 6.4e-70 235.3 0.0 1.5 1 0 0 1 1 1 1 PIG-X / PBN1 Sulfotransfer_3 PF13469.6 EGO57797.1 - 4.3e-06 27.3 0.0 0.13 12.7 0.0 3.2 3 0 0 3 3 3 2 Sulfotransferase family Mhr1 PF12829.7 EGO57798.1 - 1.9e-30 104.8 0.1 3e-30 104.1 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DUF3437 PF11919.8 EGO57798.1 - 0.028 14.3 0.5 0.093 12.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) N2227 PF07942.12 EGO57798.1 - 0.034 13.3 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein KcnmB2_inactiv PF09303.10 EGO57798.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 KCNMB2, ball and chain domain AAA_2 PF07724.14 EGO57799.1 - 1.7e-48 165.0 0.0 2.5e-46 157.9 0.0 3.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGO57799.1 - 4.6e-35 119.7 4.1 4.6e-35 119.7 4.1 4.2 2 1 1 3 3 3 1 AAA lid domain AAA PF00004.29 EGO57799.1 - 5e-28 98.2 0.3 2.2e-15 57.2 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EGO57799.1 - 2e-23 82.2 1.9 8.3e-23 80.2 1.9 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EGO57799.1 - 9.3e-17 61.3 0.0 4e-10 39.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGO57799.1 - 7.2e-13 49.0 0.8 8.9e-05 22.8 0.0 4.7 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 EGO57799.1 - 3.8e-11 43.7 15.8 3e-06 27.7 0.1 6.0 4 3 1 6 6 5 2 AAA ATPase domain Sigma54_activat PF00158.26 EGO57799.1 - 8.6e-10 38.6 0.0 1.5e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 EGO57799.1 - 2.4e-07 30.9 0.0 0.02 14.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain Clp_N PF02861.20 EGO57799.1 - 1.3e-06 28.5 11.3 6.3e-05 23.0 0.0 4.7 5 0 0 5 5 3 1 Clp amino terminal domain, pathogenicity island component AAA_7 PF12775.7 EGO57799.1 - 1.8e-06 27.6 0.0 0.014 14.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 EGO57799.1 - 2.5e-06 27.4 0.0 0.048 13.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 EGO57799.1 - 7.2e-06 26.1 3.0 0.056 13.4 0.1 4.5 3 2 0 4 4 4 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EGO57799.1 - 7.5e-06 25.5 0.1 0.14 11.6 0.1 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGO57799.1 - 1.1e-05 25.7 0.0 0.27 11.4 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGO57799.1 - 1.9e-05 25.2 2.4 0.11 13.0 0.0 3.7 3 1 1 4 4 2 2 AAA domain RuvB_N PF05496.12 EGO57799.1 - 5.5e-05 23.0 0.0 7.9 6.2 0.0 4.5 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EGO57799.1 - 7.1e-05 23.2 0.0 0.56 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 EGO57799.1 - 0.00014 22.2 3.0 0.49 10.6 0.0 4.0 3 1 1 4 4 2 2 AAA domain AAA_30 PF13604.6 EGO57799.1 - 0.00025 20.8 0.0 1.4 8.6 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 EGO57799.1 - 0.00025 21.6 14.8 0.37 11.3 0.0 4.5 5 0 0 5 5 3 1 AAA domain RsgA_GTPase PF03193.16 EGO57799.1 - 0.00025 21.0 0.3 0.52 10.2 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase AAA_3 PF07726.11 EGO57799.1 - 0.00027 20.8 0.0 1.4 8.8 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EGO57799.1 - 0.00031 20.7 0.0 0.44 10.6 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EGO57799.1 - 0.00037 20.3 0.0 0.48 10.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGO57799.1 - 0.00047 20.5 0.8 0.2 12.0 0.1 3.7 4 1 0 4 4 3 1 AAA domain ABC_tran PF00005.27 EGO57799.1 - 0.00049 20.6 0.5 0.93 10.0 0.0 3.5 3 0 0 3 3 3 1 ABC transporter Torsin PF06309.11 EGO57799.1 - 0.001 19.2 0.0 0.0064 16.6 0.0 2.1 2 0 0 2 2 2 1 Torsin T2SSE PF00437.20 EGO57799.1 - 0.0025 16.9 0.1 0.049 12.7 0.0 2.8 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 EGO57799.1 - 0.0035 17.0 0.0 3.7 7.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 EGO57799.1 - 0.0052 16.7 0.0 0.43 10.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain ResIII PF04851.15 EGO57799.1 - 0.0059 16.6 0.0 1.2 9.1 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Roc PF08477.13 EGO57799.1 - 0.0082 16.4 0.0 2.4 8.4 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 EGO57799.1 - 0.0097 15.8 0.1 5.3 6.9 0.0 2.9 2 1 0 2 2 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 EGO57799.1 - 0.0099 15.8 0.0 0.33 10.9 0.0 3.1 3 0 0 3 3 2 1 NTPase Ran-binding PF05508.11 EGO57799.1 - 0.016 14.3 1.2 0.042 12.8 1.2 1.7 1 0 0 1 1 1 0 RanGTP-binding protein SRP54 PF00448.22 EGO57799.1 - 0.034 13.8 0.0 7.2 6.2 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_6 PF12774.7 EGO57799.1 - 0.061 12.3 0.1 7.2 5.5 0.0 3.1 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region ATP_bind_1 PF03029.17 EGO57799.1 - 0.086 12.6 0.0 8.2 6.1 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EGO57799.1 - 0.11 12.2 0.0 7.1 6.4 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GAS PF13851.6 EGO57799.1 - 0.15 11.4 18.5 0.01 15.2 11.8 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_25 PF13481.6 EGO57799.1 - 0.16 11.6 2.5 6 6.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain Exonuc_VII_L PF02601.15 EGO57799.1 - 0.23 11.0 7.0 0.57 9.7 7.0 1.7 1 0 0 1 1 1 0 Exonuclease VII, large subunit FTA4 PF13093.6 EGO57799.1 - 0.32 10.8 7.6 0.35 10.7 5.5 2.2 2 0 0 2 2 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Spc7 PF08317.11 EGO57799.1 - 0.46 9.3 14.8 1.3 7.9 14.8 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 EGO57799.1 - 1.1 8.2 8.1 2.3 7.2 8.1 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Macoilin PF09726.9 EGO57799.1 - 2 6.9 15.5 0.22 10.0 11.1 1.6 2 0 0 2 2 2 0 Macoilin family V_ATPase_I PF01496.19 EGO57799.1 - 4.5 5.1 15.4 0.7 7.7 10.9 1.9 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 EGO57799.1 - 9 5.5 14.9 22 4.3 14.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0113_N PF17833.1 EGO57800.1 - 1.9e-24 86.0 0.0 2.6e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EGO57800.1 - 1.9e-23 82.5 0.0 2.8e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 EGO57800.1 - 0.054 13.5 0.0 0.078 13.0 0.0 1.2 1 0 0 1 1 1 0 PUA domain Sortase PF04203.13 EGO57800.1 - 0.099 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Sortase domain AA_kinase PF00696.28 EGO57801.1 - 1.2e-41 142.9 1.5 1.8e-41 142.4 1.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EGO57801.1 - 1.2e-14 54.0 0.2 3e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 PUA domain Peptidase_M76 PF09768.9 EGO57802.1 - 3.3e-66 222.3 1.1 4.1e-66 222.0 1.1 1.1 1 0 0 1 1 1 1 Peptidase M76 family DUF2268 PF10026.9 EGO57802.1 - 0.018 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) SprT-like PF10263.9 EGO57802.1 - 0.026 14.4 1.3 0.049 13.5 0.7 1.7 1 1 0 1 1 1 0 SprT-like family Peptidase_M91 PF14891.6 EGO57802.1 - 0.032 14.6 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 Effector protein Tox-MPTase2 PF15638.6 EGO57802.1 - 0.098 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Pkinase PF00069.25 EGO57803.1 - 5.3e-72 242.4 0.0 6.6e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57803.1 - 3.2e-44 151.2 0.0 4.3e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO57803.1 - 7.6e-07 28.7 0.0 3.2e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGO57803.1 - 0.00096 18.6 0.1 0.0015 17.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGO57803.1 - 0.021 14.4 0.0 0.07 12.7 0.0 1.7 1 1 1 2 2 2 0 RIO1 family FTA2 PF13095.6 EGO57803.1 - 0.088 12.4 0.0 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 EGO57803.1 - 0.088 12.3 0.0 0.2 11.1 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL TIP41 PF04176.13 EGO57804.1 - 7.7e-69 230.6 0.0 1.1e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family DUF3439 PF11921.8 EGO57804.1 - 2.7 8.0 5.3 6.4 6.8 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF2749 PF10907.8 EGO57805.1 - 0.87 9.8 3.6 1.9 8.7 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) FUN14 PF04930.15 EGO57806.1 - 2.6e-06 27.8 2.6 2.3e-05 24.7 3.3 2.1 2 1 0 2 2 2 1 FUN14 family Creatinase_N_2 PF16189.5 EGO57808.1 - 2.1e-55 187.2 0.1 6.4e-54 182.4 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EGO57808.1 - 3.3e-45 154.3 0.0 4.6e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EGO57808.1 - 1.6e-22 80.5 0.0 6.1e-17 62.5 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EGO57808.1 - 4e-20 71.6 0.1 1.2e-19 70.1 0.1 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 DUF1335 PF07056.11 EGO57808.1 - 0.096 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) tRNA-synt_1b PF00579.25 EGO57809.1 - 8.1e-49 166.5 0.0 9.1e-25 87.6 0.0 2.5 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) Importin_rep_3 PF18806.1 EGO57809.1 - 4.8e-05 23.3 0.0 0.00024 21.1 0.0 2.3 1 0 0 1 1 1 1 Importin 13 repeat Xpo1 PF08389.12 EGO57809.1 - 0.084 12.9 0.1 0.35 10.9 0.1 2.2 1 0 0 1 1 1 0 Exportin 1-like protein Get5_C PF18514.1 EGO57809.1 - 0.21 11.3 1.2 0.37 10.6 0.1 2.0 2 0 0 2 2 2 0 Get5 C-terminal domain Ribosomal_S10 PF00338.22 EGO57810.1 - 1.4e-25 89.4 0.0 2.5e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Med3 PF11593.8 EGO57810.1 - 4.5 6.4 6.9 5.9 6.0 6.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Fcf2 PF08698.11 EGO57811.1 - 4.9e-32 110.2 0.5 1.5e-31 108.6 0.1 2.0 2 1 1 3 3 3 1 Fcf2 pre-rRNA processing Pex14_N PF04695.13 EGO57811.1 - 0.011 16.4 0.5 0.017 15.8 0.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CBFD_NFYB_HMF PF00808.23 EGO57812.1 - 1.9e-19 69.7 0.5 3.7e-19 68.8 0.5 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGO57812.1 - 1.1e-14 54.9 1.0 1.4e-14 54.6 0.1 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EGO57812.1 - 0.036 14.4 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Pol_alpha_B_N PF08418.10 EGO57812.1 - 0.085 12.8 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Sec15 PF04091.12 EGO57813.1 - 1.1e-112 376.5 2.6 2.2e-112 375.6 2.6 1.5 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like DUF2451 PF10474.9 EGO57813.1 - 4.6e-06 26.6 1.0 2.1e-05 24.5 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) DUF4201 PF13870.6 EGO57813.1 - 0.00059 19.6 4.4 0.00059 19.6 4.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) DUF3510 PF12022.8 EGO57813.1 - 0.0031 17.9 3.1 1.4 9.3 0.2 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF3510) COG5 PF10392.9 EGO57813.1 - 0.015 15.4 5.3 0.086 13.0 3.1 2.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 EGO57813.1 - 0.061 13.2 6.5 0.028 14.3 1.8 2.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain BORCS8 PF10167.9 EGO57813.1 - 0.31 11.0 6.1 0.37 10.7 1.5 3.2 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 8 COG2 PF06148.11 EGO57813.1 - 0.46 10.6 17.3 0.61 10.2 3.1 4.3 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Rbsn PF11464.8 EGO57813.1 - 1.3 8.8 8.0 0.13 12.0 0.4 3.2 3 0 0 3 3 3 0 Rabenosyn Rab binding domain Hrs_helical PF12210.8 EGO57813.1 - 1.4 9.5 7.9 6.6 7.3 0.4 3.1 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate ApoLp-III PF07464.11 EGO57813.1 - 2.4 8.2 11.8 0.19 11.8 3.1 3.0 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) RRM_2 PF04059.12 EGO57814.1 - 2.6e-06 27.6 0.1 4.8e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 Sad1_UNC PF07738.13 EGO57815.1 - 5.4e-35 120.3 0.1 9.6e-35 119.5 0.1 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal NRDE-2 PF08424.10 EGO57816.1 - 2.6e-99 332.4 0.2 2.6e-99 332.4 0.2 2.8 4 0 0 4 4 4 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EGO57816.1 - 0.0019 18.8 0.2 11 7.1 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Voltage_CLC PF00654.20 EGO57819.1 - 4.8e-92 308.9 20.9 4.8e-92 308.9 20.9 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel Peptidase_M18 PF02127.15 EGO57820.1 - 2.4e-173 576.9 0.0 2.9e-173 576.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EGO57820.1 - 0.00014 21.0 0.0 0.00042 19.4 0.0 1.8 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase tRNA-synt_His PF13393.6 EGO57820.1 - 0.18 11.0 0.0 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Caldesmon PF02029.15 EGO57822.1 - 0.055 12.2 42.9 0.049 12.4 16.3 2.3 2 0 0 2 2 2 0 Caldesmon BAF1_ABF1 PF04684.13 EGO57822.1 - 0.063 12.3 37.1 0.64 9.0 16.0 2.4 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF2052 PF09747.9 EGO57822.1 - 0.64 10.1 47.7 0.094 12.8 15.6 2.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) UPF0565 PF10561.9 EGO57822.1 - 1.6 7.9 20.4 3.8 6.6 6.7 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 DUF4471 PF14740.6 EGO57822.1 - 2.2 7.4 31.0 4.7 6.3 10.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) DUF4746 PF15928.5 EGO57822.1 - 2.4 7.5 33.5 3.5 7.0 9.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) SET PF00856.28 EGO57822.1 - 6.4 7.1 9.7 17 5.8 1.8 2.9 2 0 0 2 2 2 0 SET domain Whi5 PF08528.11 EGO57823.1 - 2.6e-10 39.7 0.1 4.5e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Whi5 like Erf4 PF10256.9 EGO57824.1 - 9.3e-39 132.1 0.0 1.3e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4203 PF13886.6 EGO57828.1 - 2.3e-20 73.1 20.3 3e-20 72.8 20.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2070 PF09843.9 EGO57828.1 - 0.1 10.8 6.4 0.14 10.4 6.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) UbiA PF01040.18 EGO57828.1 - 0.36 10.1 12.6 0.48 9.7 12.6 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family Borrelia_P13 PF05628.12 EGO57828.1 - 0.47 10.4 4.5 0.75 9.8 0.2 2.2 2 0 0 2 2 2 0 Borrelia membrane protein P13 AMP-binding PF00501.28 EGO57829.1 - 8.8e-75 251.9 0.0 1.1e-74 251.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO57829.1 - 3.6e-20 72.7 0.0 7.2e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro_1 PF00232.18 EGO57830.1 - 6.9e-153 509.3 0.0 8.5e-153 509.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 TMEM82 PF15816.5 EGO57831.1 - 0.03 13.3 0.0 0.04 12.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 82 POB3_N PF17292.2 EGO57832.1 - 1.6e-32 111.8 0.5 2.5e-30 104.7 0.1 3.2 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 EGO57832.1 - 7e-30 102.7 0.2 4.1e-29 100.3 0.0 2.4 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EGO57832.1 - 2.8e-23 82.2 0.0 2.8e-22 78.9 0.0 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like RE_Bsp6I PF09504.10 EGO57832.1 - 0.09 12.4 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 Bsp6I restriction endonuclease Xpo1 PF08389.12 EGO57833.1 - 6e-42 143.2 4.3 7e-41 139.8 0.5 3.4 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.22 EGO57833.1 - 0.00012 22.1 0.5 4.3 7.9 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 EGO57833.1 - 0.03 14.9 2.3 71 4.1 0.0 5.1 5 1 1 6 6 6 0 HEAT-like repeat CDP-OH_P_transf PF01066.21 EGO57835.1 - 2.7e-15 56.9 0.3 2.7e-15 56.9 0.3 2.1 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase EKLF_TAD1 PF16832.5 EGO57835.1 - 0.56 10.1 2.5 1.1 9.2 2.5 1.4 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 GIDA PF01134.22 EGO57836.1 - 4.6e-157 523.1 0.0 5.6e-157 522.8 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EGO57836.1 - 7.7e-65 219.0 0.0 1.1e-64 218.5 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 EGO57836.1 - 4.7e-07 29.5 0.6 7.9e-07 28.8 0.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO57836.1 - 3.7e-05 23.1 0.8 7.8e-05 22.0 0.8 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGO57836.1 - 0.0023 17.1 6.6 0.0051 15.9 6.0 1.9 1 1 1 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EGO57836.1 - 0.0029 16.9 0.5 0.0069 15.7 0.5 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EGO57836.1 - 0.061 12.0 1.0 0.27 9.9 0.9 1.9 2 0 0 2 2 2 0 HI0933-like protein Hyccin PF09790.9 EGO57836.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Hyccin SSB PF00436.25 EGO57837.1 - 8.1e-20 70.8 0.0 1e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Cleaved_Adhesin PF07675.11 EGO57837.1 - 0.14 12.1 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Cleaved Adhesin Domain STE3 PF02076.15 EGO57838.1 - 8.2e-47 159.8 11.9 7.5e-39 133.7 2.4 2.2 1 1 1 2 2 2 2 Pheromone A receptor CAP_N PF01213.19 EGO57838.1 - 8.1 5.8 6.5 22 4.4 0.4 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PBD PF00786.28 EGO57840.1 - 0.0092 16.3 0.3 0.033 14.5 0.3 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain DUF4698 PF15769.5 EGO57840.1 - 2.4 7.1 4.5 4.5 6.2 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) HLH PF00010.26 EGO57843.1 - 2e-11 43.7 0.0 3.9e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4647 PF15504.6 EGO57843.1 - 0.96 8.5 5.9 1.9 7.5 5.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4647) Histone PF00125.24 EGO57844.1 - 7.4e-42 142.8 0.8 8.9e-42 142.6 0.8 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGO57844.1 - 2.7e-05 24.3 0.0 4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGO57844.1 - 0.00012 22.3 0.1 0.00018 21.8 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGO57844.1 - 0.013 15.8 0.4 0.021 15.1 0.4 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGO57844.1 - 0.13 12.3 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DER1 PF04511.15 EGO57845.1 - 6.6e-53 179.5 7.3 7.6e-53 179.3 7.3 1.0 1 0 0 1 1 1 1 Der1-like family ARD PF03079.14 EGO57846.1 - 5.8e-43 146.8 0.2 7.3e-43 146.5 0.2 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EGO57846.1 - 4.6e-08 32.7 0.0 7.4e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EGO57846.1 - 9.6e-06 25.5 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain adh_short PF00106.25 EGO57847.1 - 2.3e-32 112.0 0.0 3.1e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO57847.1 - 1e-22 80.8 0.0 1.4e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO57847.1 - 2.4e-11 43.9 0.0 3.4e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO57847.1 - 3.3e-08 33.3 0.1 8e-08 32.0 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO57847.1 - 1.5e-06 27.8 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGO57847.1 - 6e-06 25.6 0.0 7.5e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EGO57847.1 - 0.0013 18.9 0.0 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EGO57847.1 - 0.0032 16.5 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGO57847.1 - 0.0072 15.5 0.0 0.014 14.5 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 EGO57847.1 - 0.057 13.0 0.1 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family F420_oxidored PF03807.17 EGO57847.1 - 0.061 13.9 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 EGO57847.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_2 PF03446.15 EGO57847.1 - 0.16 12.1 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PIEZO PF15917.5 EGO57848.1 - 6.5 6.2 10.3 7 6.1 10.3 1.0 1 0 0 1 1 1 0 Piezo His_biosynth PF00977.21 EGO57849.1 - 1.6e-36 125.9 0.0 2.1e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 EGO57849.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.6 EGO57850.1 - 2.3 8.5 56.0 14 6.0 41.7 4.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4602) Anillin PF08174.11 EGO57851.1 - 2.2e-16 60.6 0.0 6.3e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 EGO57851.1 - 9.3e-08 32.5 0.0 2.8e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 PH domain Pyr_redox_2 PF07992.14 EGO57852.1 - 7.3e-42 143.6 0.0 6.3e-38 130.7 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO57852.1 - 6.7e-13 49.0 0.0 8.8e-11 42.2 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGO57852.1 - 0.0013 18.3 0.0 0.29 10.7 0.0 3.3 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO57852.1 - 0.0028 17.0 0.0 2.4 7.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M24 PF00557.24 EGO57853.1 - 7.6e-28 97.6 0.0 8.6e-17 61.5 0.0 2.3 2 1 0 2 2 2 2 Metallopeptidase family M24 AMP_N PF05195.16 EGO57853.1 - 3.8e-19 68.6 0.0 9.8e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Zn_clus PF00172.18 EGO57854.1 - 3.5e-11 43.0 13.8 6.7e-11 42.1 13.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGO57854.1 - 5.7e-09 35.4 0.0 0.0003 19.9 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain SelK_SelG PF10961.8 EGO57854.1 - 0.026 15.1 1.1 0.12 13.0 1.1 2.1 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Gal4_dimer PF03902.13 EGO57854.1 - 0.21 11.8 0.7 0.92 9.7 0.1 2.3 3 0 0 3 3 3 0 Gal4-like dimerisation domain RPN7 PF10602.9 EGO57855.1 - 5.5e-47 159.7 0.0 8.9e-47 159.0 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EGO57855.1 - 2.8e-16 59.9 0.0 7.1e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 EGO57855.1 - 0.036 14.2 1.3 2.4 8.5 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Prp18 PF02840.15 EGO57856.1 - 1.8e-52 177.2 0.0 1.8e-52 177.2 0.0 1.8 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 EGO57856.1 - 5.2e-11 41.9 0.3 5.2e-11 41.9 0.3 2.9 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like MFAP1 PF06991.11 EGO57856.1 - 0.012 15.5 10.8 0.026 14.4 10.8 1.5 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing LEM PF03020.15 EGO57856.1 - 0.044 13.4 0.5 5.9 6.5 0.0 2.5 2 0 0 2 2 2 0 LEM domain CNDH2_M PF16869.5 EGO57856.1 - 0.24 12.1 5.2 0.53 11.0 5.2 1.6 1 0 0 1 1 1 0 PF16858 DUF966 PF06136.13 EGO57856.1 - 1.6 8.3 7.1 2.6 7.7 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SAP18 PF06487.12 EGO57857.1 - 9.9e-36 123.0 0.0 1.3e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) LCAT PF02450.15 EGO57858.1 - 5.8e-05 22.4 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 EGO57858.1 - 0.008 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EGO57858.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGO57858.1 - 0.032 13.9 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 EGO57858.1 - 0.071 13.7 0.1 0.44 11.1 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family LAP1C PF05609.12 EGO57858.1 - 3.4 6.6 7.5 6.1 5.8 7.5 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Lectin_leg-like PF03388.13 EGO57859.1 - 2.6e-24 85.8 0.0 8.2e-24 84.2 0.0 1.7 2 0 0 2 2 2 1 Legume-like lectin family SUIM_assoc PF16619.5 EGO57859.1 - 0.0012 18.8 2.6 0.0027 17.7 2.6 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 FlaC_arch PF05377.11 EGO57859.1 - 0.024 15.0 0.5 1.4 9.4 0.3 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ANAPC_CDC26 PF10471.9 EGO57859.1 - 0.039 14.8 7.7 0.083 13.7 7.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Prominin PF05478.11 EGO57859.1 - 0.064 11.2 0.7 0.091 10.7 0.7 1.2 1 0 0 1 1 1 0 Prominin DUF4175 PF13779.6 EGO57859.1 - 0.14 10.0 7.1 0.18 9.7 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3216 PF11505.8 EGO57859.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Spt20 PF12090.8 EGO57859.1 - 0.31 10.6 9.9 0.49 10.0 9.9 1.3 1 0 0 1 1 1 0 Spt20 family CENP-Q PF13094.6 EGO57859.1 - 0.43 10.8 9.2 0.74 10.0 2.9 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Taxilin PF09728.9 EGO57859.1 - 0.53 9.4 8.4 0.05 12.8 0.7 2.0 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF4407 PF14362.6 EGO57859.1 - 0.87 8.9 5.7 1.3 8.3 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 EGO57859.1 - 2.6 7.3 5.9 3.8 6.8 5.9 1.2 1 0 0 1 1 1 0 FAM76 protein DUF1664 PF07889.12 EGO57859.1 - 6.5 6.8 7.0 3.2 7.8 0.2 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Alg6_Alg8 PF03155.15 EGO57861.1 - 2.6e-176 587.3 26.2 3e-176 587.1 26.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF92 PF01940.16 EGO57861.1 - 0.23 10.8 1.9 5.6 6.3 0.7 2.5 2 0 0 2 2 2 0 Integral membrane protein DUF92 YqhR PF11085.8 EGO57861.1 - 1.4 8.8 11.6 0.16 11.9 3.3 2.5 2 0 0 2 2 2 0 Conserved membrane protein YqhR WAC_Acf1_DNA_bd PF10537.9 EGO57862.1 - 8.4e-24 84.0 0.4 6.4e-13 49.1 0.0 3.1 1 1 1 2 2 2 2 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EGO57862.1 - 3.3e-18 66.0 0.2 3.3e-18 66.0 0.2 3.9 4 0 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EGO57862.1 - 7.1e-17 61.5 0.5 1.2e-16 60.8 0.5 1.3 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 EGO57862.1 - 5.3e-09 35.4 0.0 1.6e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF2721 PF11026.8 EGO57863.1 - 2.1 8.3 10.5 15 5.4 7.7 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) HK PF02110.15 EGO57864.1 - 1.2e-75 254.1 0.1 1.8e-75 253.5 0.1 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EGO57864.1 - 6.6e-57 191.8 1.8 1e-56 191.1 1.8 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 EGO57864.1 - 0.00017 21.2 0.1 0.00038 20.0 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 EGO57864.1 - 0.0036 16.7 0.0 0.0084 15.5 0.0 1.6 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase ADH_zinc_N PF00107.26 EGO57864.1 - 0.019 15.0 1.6 0.19 11.7 0.0 2.8 2 1 1 3 3 3 0 Zinc-binding dehydrogenase DUF2347 PF09804.9 EGO57865.1 - 5.4e-101 337.9 0.0 6.9e-101 337.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 EGO57865.1 - 2.6e-67 227.0 0.4 3.8e-67 226.4 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.10 EGO57865.1 - 0.00019 21.3 0.1 0.0018 18.2 0.1 2.1 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 EGO57865.1 - 0.0046 15.7 0.0 0.041 12.6 0.0 2.1 2 0 0 2 2 2 1 Transport protein Avl9 Acyltransferase PF01553.21 EGO57866.1 - 1.2e-32 112.3 0.0 2.1e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DnaJ PF00226.31 EGO57867.1 - 2.7e-16 59.4 0.8 7e-16 58.1 0.8 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 EGO57867.1 - 4.7e-09 35.8 0.0 0.0015 17.7 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain Astro_capsid_p PF12226.8 EGO57867.1 - 0.4 9.8 5.3 0.7 9.0 5.3 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TPR_1 PF00515.28 EGO57868.1 - 2.1e-47 157.1 10.0 2e-10 40.0 0.1 7.1 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGO57868.1 - 2e-41 136.8 13.7 1.2e-06 28.2 0.0 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 EGO57868.1 - 4.5e-30 103.1 13.1 4.9e-07 29.3 0.7 6.4 4 1 2 6 6 6 5 TPR repeat DnaJ PF00226.31 EGO57868.1 - 3.7e-27 94.2 2.9 9.8e-27 92.9 2.9 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.6 EGO57868.1 - 2.2e-25 89.0 3.5 9.7e-08 32.5 0.4 5.5 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGO57868.1 - 1.7e-24 84.0 6.2 4.9e-06 26.3 0.1 7.3 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGO57868.1 - 1.2e-22 80.2 12.3 8.7e-10 39.0 0.0 6.0 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 EGO57868.1 - 9.5e-20 69.5 12.5 5.8e-05 23.2 0.0 7.1 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGO57868.1 - 1e-19 69.0 1.3 0.021 14.8 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGO57868.1 - 3.8e-19 67.7 12.9 0.00018 22.0 0.0 8.5 5 3 4 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGO57868.1 - 1.1e-17 64.1 10.0 1.2e-05 25.5 0.1 5.8 5 1 1 6 6 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO57868.1 - 2.4e-16 59.7 3.5 1.9e-07 31.2 0.2 3.8 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGO57868.1 - 3.6e-13 49.4 7.7 0.00024 21.2 0.1 6.0 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 EGO57868.1 - 2.5e-09 37.2 13.1 0.71 10.6 0.0 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 EGO57868.1 - 4.3e-08 32.7 8.0 0.017 14.4 0.3 4.4 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGO57868.1 - 3.6e-07 29.8 11.9 0.89 9.5 0.7 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat BTAD PF03704.17 EGO57868.1 - 8.5e-05 23.0 7.5 0.39 11.1 0.1 4.6 4 1 0 4 4 3 1 Bacterial transcriptional activator domain TPR_4 PF07721.14 EGO57868.1 - 8.7e-05 22.8 0.5 8.1 7.4 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGO57868.1 - 0.00025 21.3 4.2 1.4 9.3 0.0 4.5 2 2 1 4 4 4 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 EGO57868.1 - 0.0057 16.7 0.3 8.6 6.5 0.0 3.5 3 1 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region SRP_TPR_like PF17004.5 EGO57868.1 - 0.0059 16.6 2.1 2.5 8.1 0.1 3.3 3 1 1 4 4 3 1 Putative TPR-like repeat RRM_3 PF08777.11 EGO57868.1 - 0.014 15.4 0.2 0.049 13.7 0.1 1.9 2 0 0 2 2 1 0 RNA binding motif Alkyl_sulf_dimr PF14863.6 EGO57868.1 - 0.035 14.6 0.4 4.4 7.8 0.0 2.9 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation SHNi-TPR PF10516.9 EGO57868.1 - 0.056 12.9 1.8 56 3.3 0.0 4.5 5 0 0 5 5 4 0 SHNi-TPR DUF3856 PF12968.7 EGO57868.1 - 0.17 11.9 1.7 51 3.9 0.0 4.7 4 2 0 4 4 4 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.6 EGO57868.1 - 0.74 9.9 20.4 2.4 8.3 0.0 5.3 7 0 0 7 7 5 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 EGO57868.1 - 0.76 9.9 9.4 21 5.3 0.2 4.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPM_phosphatase PF04536.14 EGO57868.1 - 0.91 9.7 2.5 17 5.6 0.1 3.1 2 1 1 3 3 3 0 TPM domain EF-hand_6 PF13405.6 EGO57869.1 - 7.6e-11 41.0 0.6 1.2e-05 24.9 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGO57869.1 - 7.5e-07 28.3 2.8 0.00062 19.1 0.1 2.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EGO57869.1 - 7.5e-06 26.3 0.0 0.038 14.5 0.0 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGO57869.1 - 3e-05 23.3 2.4 0.0031 17.0 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EGO57869.1 - 0.0001 22.5 0.0 0.33 11.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGO57869.1 - 0.00044 20.0 0.0 0.37 10.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair Afi1 PF07792.12 EGO57870.1 - 1.5e-49 167.9 0.8 2.6e-49 167.1 0.8 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 EGO57870.1 - 3.7e-36 123.5 0.0 6.5e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 EGO57870.1 - 6.2e-08 31.7 0.0 0.011 14.5 0.0 3.7 3 1 1 4 4 4 2 Transport protein Avl9 SDA1 PF05285.12 EGO57870.1 - 4.1 6.7 13.5 6.2 6.1 13.5 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 EGO57870.1 - 5.5 6.5 11.4 0.99 8.9 6.9 2.0 2 0 0 2 2 2 0 PPP4R2 DUF4502 PF14950.6 EGO57870.1 - 6.4 6.1 8.0 12 5.2 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) Rib_recp_KP_reg PF05104.12 EGO57870.1 - 9.5 7.2 8.0 0.2 12.7 1.0 1.7 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Esterase PF00756.20 EGO57871.1 - 1.2e-54 185.6 0.0 1.5e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EGO57871.1 - 1.2e-05 24.9 0.2 1.8e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 EGO57871.1 - 0.014 14.9 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 EGO57871.1 - 0.015 14.5 0.1 0.03 13.6 0.1 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EGO57871.1 - 0.018 13.9 0.0 0.039 12.9 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S15 PF02129.18 EGO57871.1 - 0.055 13.1 0.4 0.55 9.8 0.3 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.25 EGO57871.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 EGO57871.1 - 0.19 11.2 1.1 1.6 8.2 1.1 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family GARS_A PF01071.19 EGO57875.1 - 4.9e-53 179.8 0.0 8.5e-53 179.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 EGO57875.1 - 1.3e-37 129.3 0.2 2.9e-37 128.2 0.2 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 EGO57875.1 - 1.5e-27 95.7 0.2 6.7e-27 93.6 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EGO57875.1 - 4.3e-14 52.9 2.0 1.4e-13 51.3 2.0 1.9 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain KTI12 PF08433.10 EGO57876.1 - 8.6e-66 222.2 0.0 1.4e-65 221.5 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EGO57876.1 - 0.0012 19.0 0.0 0.0027 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF4805 PF16063.5 EGO57876.1 - 0.0018 17.6 2.0 0.0037 16.6 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4805) AAA_22 PF13401.6 EGO57876.1 - 0.033 14.5 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Dicty_REP PF05086.12 EGO57876.1 - 0.31 9.0 3.5 0.38 8.7 3.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Zn_clus PF00172.18 EGO57877.1 - 2.3e-07 30.8 11.5 5.8e-07 29.5 11.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGO57877.1 - 7.3e-07 28.3 0.1 0.0021 16.9 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Pro_isomerase PF00160.21 EGO57878.1 - 2.2e-43 148.3 0.0 4e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 EGO57878.1 - 1.1e-05 25.5 0.0 3.7e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 EGO57878.1 - 0.00038 20.5 0.0 0.00092 19.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Lung_7-TM_R PF06814.13 EGO57879.1 - 1.9e-69 234.2 15.0 2.5e-69 233.8 15.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor FtsH_ext PF06480.15 EGO57879.1 - 0.27 11.6 1.0 1.9 8.9 1.0 2.5 1 0 0 1 1 1 0 FtsH Extracellular PGF-CTERM PF18204.1 EGO57879.1 - 0.33 11.0 2.3 0.41 10.7 0.6 2.1 2 0 0 2 2 2 0 PGF-CTERM motif DUF4131 PF13567.6 EGO57879.1 - 1.9 8.1 13.2 1 9.0 1.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) SurA_N_3 PF13624.6 EGO57879.1 - 3.1 7.6 4.0 16 5.3 0.3 3.1 2 1 1 3 3 3 0 SurA N-terminal domain Methyltransf_28 PF02636.17 EGO57880.1 - 1.3e-89 300.3 0.0 3.4e-89 299.0 0.0 1.6 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase SPX PF03105.19 EGO57880.1 - 0.011 15.7 2.6 0.015 15.2 2.6 1.3 1 0 0 1 1 1 0 SPX domain SR-25 PF10500.9 EGO57880.1 - 1.1 8.8 23.6 1.9 8.0 23.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 EGO57880.1 - 1.2 7.6 2.4 1.7 7.1 2.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF508 PF04370.12 EGO57880.1 - 2.6 7.8 7.8 5 6.9 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Use1 PF09753.9 EGO57881.1 - 1.7e-08 34.5 7.2 1.1e-07 31.9 7.2 2.1 1 1 0 1 1 1 1 Membrane fusion protein Use1 GldM_N PF12081.8 EGO57881.1 - 0.024 14.7 1.8 0.038 14.1 0.2 2.0 2 0 0 2 2 2 0 GldM N-terminal domain Snapin_Pallidin PF14712.6 EGO57881.1 - 0.089 13.2 0.2 0.089 13.2 0.2 2.7 2 1 0 2 2 2 0 Snapin/Pallidin DUF5130 PF17174.4 EGO57881.1 - 0.11 12.7 0.4 0.33 11.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5130) SpecificRecomb PF10136.9 EGO57881.1 - 0.23 9.7 1.4 0.2 9.9 0.2 1.5 2 0 0 2 2 2 0 Site-specific recombinase COPI_C PF06957.11 EGO57881.1 - 0.3 9.8 2.6 0.47 9.2 2.6 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Vps53_N PF04100.12 EGO57881.1 - 0.53 9.2 6.4 0.25 10.3 0.8 2.1 2 0 0 2 2 2 0 Vps53-like, N-terminal GREB1 PF15782.5 EGO57881.1 - 1 6.4 9.1 1.3 6.1 9.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Totivirus_coat PF05518.11 EGO57881.1 - 4.4 5.2 7.2 6.2 4.7 7.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein BRCT PF00533.26 EGO57882.1 - 0.0069 16.7 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGO57882.1 - 0.022 14.7 0.1 0.046 13.7 0.1 1.6 1 0 0 1 1 1 0 twin BRCT domain BRCT_2 PF16589.5 EGO57882.1 - 0.026 14.9 0.0 0.05 14.0 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EGO57882.1 - 0.068 13.5 0.1 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Zeta_toxin PF06414.12 EGO57883.1 - 5.4e-56 189.0 0.0 7.1e-56 188.6 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 EGO57883.1 - 0.0018 18.5 0.0 0.007 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO57883.1 - 0.0027 18.1 0.0 0.0047 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGO57883.1 - 0.032 14.5 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EGO57883.1 - 0.047 13.4 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 EGO57883.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DGCR6 PF07324.11 EGO57883.1 - 0.058 13.0 0.0 0.083 12.5 0.0 1.1 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein PEP_mutase PF13714.6 EGO57884.1 - 1.3e-49 168.9 0.3 1.5e-49 168.6 0.3 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EGO57884.1 - 1.1e-20 73.6 0.5 1.5e-20 73.2 0.5 1.1 1 0 0 1 1 1 1 Isocitrate lyase family MTHFR PF02219.17 EGO57884.1 - 0.025 13.9 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase DUF3543 PF12063.8 EGO57885.1 - 6.4e-89 297.6 1.4 1.1e-88 296.8 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 EGO57885.1 - 4.2e-63 213.2 0.0 7.2e-63 212.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57885.1 - 4.2e-42 144.2 0.0 7.7e-42 143.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_transf_22 PF03901.17 EGO57889.1 - 1.1e-74 252.2 24.6 1.2e-74 252.0 24.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ARL6IP6 PF15062.6 EGO57889.1 - 0.15 12.2 0.7 0.44 10.7 0.7 1.8 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Aminotran_3 PF00202.21 EGO57890.1 - 1.8e-119 399.0 0.0 2.1e-119 398.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EGO57890.1 - 0.00022 20.6 0.0 0.00047 19.5 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EGO57890.1 - 0.0022 17.3 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.16 EGO57891.1 - 1.3e-36 126.3 28.5 1.3e-36 126.3 28.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 EGO57891.1 - 0.14 11.9 4.3 6.8 6.4 0.0 2.8 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RhoGAP PF00620.27 EGO57892.1 - 1.8e-38 131.7 0.0 3.8e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PADR1 PF08063.12 EGO57893.1 - 0.03 14.1 0.1 0.075 12.8 0.1 1.7 1 0 0 1 1 1 0 PADR1 (NUC008) domain zf-Tim10_DDP PF02953.15 EGO57894.1 - 6.1e-17 61.0 0.6 7.8e-17 60.7 0.6 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger HATPase_c_5 PF14501.6 EGO57894.1 - 0.059 13.3 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 GHKL domain Nup188_C PF18378.1 EGO57895.1 - 1.8e-140 468.0 0.0 3.8e-140 466.9 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 EGO57895.1 - 3.1e-52 177.7 1.1 3.3e-35 121.3 0.0 2.4 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.21 EGO57896.1 - 9.9e-101 336.2 0.0 1.6e-100 335.4 0.0 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EGO57896.1 - 1.2e-55 188.4 0.3 1.6e-51 174.9 0.2 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 EGO57896.1 - 3.9e-47 160.5 0.0 7.4e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGO57896.1 - 0.00053 19.8 0.8 0.01 15.6 0.8 2.4 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 EGO57896.1 - 0.0022 17.8 0.7 0.041 13.7 0.0 3.1 4 0 0 4 4 4 1 Quinolinate phosphoribosyl transferase, C-terminal domain Pex14_N PF04695.13 EGO57897.1 - 0.25 12.0 15.0 1.8 9.2 7.6 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1899 PF08953.11 EGO57898.1 - 6.3e-32 109.3 0.0 1.1e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EGO57898.1 - 6.3e-20 70.8 0.2 1.5e-19 69.6 0.2 1.7 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EGO57898.1 - 2e-16 60.1 7.7 0.00013 22.7 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO57898.1 - 5.9e-07 29.7 0.1 0.0027 18.0 0.1 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO57898.1 - 8.3e-05 21.7 0.0 0.005 15.8 0.1 2.4 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGO57898.1 - 0.00024 19.9 0.4 0.017 13.8 0.3 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 EGO57898.1 - 0.00044 20.2 0.0 0.0082 16.0 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Laminin_I PF06008.14 EGO57898.1 - 0.043 13.5 0.1 0.065 12.9 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain I SlyX PF04102.12 EGO57898.1 - 2.9 8.6 5.2 5 7.8 3.4 2.2 2 0 0 2 2 2 0 SlyX SIR2 PF02146.17 EGO57899.1 - 4.8e-26 91.8 0.0 9.5e-26 90.8 0.0 1.5 1 1 0 1 1 1 1 Sir2 family Spectrin_like PF18373.1 EGO57899.1 - 0.18 11.9 0.0 0.6 10.2 0.0 1.9 1 1 1 2 2 2 0 Spectrin like domain Peptidase_C50 PF03568.17 EGO57900.1 - 5.3e-159 529.6 0.0 1.1e-158 528.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 EGO57900.1 - 5.1e-06 26.1 0.3 4.4e-05 23.0 0.0 2.6 3 0 0 3 3 3 1 CHAT domain TPR_12 PF13424.6 EGO57900.1 - 2.7e-05 24.3 22.9 0.03 14.6 3.1 6.6 6 1 1 7 7 7 4 Tetratricopeptide repeat CDH-cyt PF16010.5 EGO57901.1 - 1.2e-63 214.1 6.2 2.4e-63 213.1 6.2 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_C PF05199.13 EGO57901.1 - 5.5e-30 104.8 0.7 1.2e-29 103.7 0.7 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EGO57901.1 - 9.9e-25 87.5 0.1 2.3e-24 86.3 0.1 1.7 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGO57901.1 - 9.5e-09 34.8 1.3 0.0019 17.3 0.7 2.4 2 0 0 2 2 2 2 FAD binding domain CBM_1 PF00734.18 EGO57901.1 - 2.2e-08 33.9 14.2 6e-08 32.5 14.2 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_oxidored PF12831.7 EGO57901.1 - 0.00027 20.4 0.0 0.026 13.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 EGO57901.1 - 0.00054 19.6 2.6 0.012 15.2 2.6 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO57901.1 - 0.0017 17.7 0.0 0.0039 16.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DOMON PF03351.17 EGO57901.1 - 0.0023 18.1 0.1 0.0071 16.6 0.1 1.9 1 0 0 1 1 1 1 DOMON domain HI0933_like PF03486.14 EGO57901.1 - 0.0037 16.0 0.2 0.0072 15.1 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EGO57901.1 - 0.0048 17.1 0.1 0.013 15.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGO57901.1 - 0.034 14.7 0.5 0.71 10.5 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO57901.1 - 0.042 13.1 0.5 0.15 11.3 0.9 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGO57901.1 - 0.094 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 2OG-FeII_Oxy_3 PF13640.6 EGO57902.1 - 1.3e-08 35.6 0.1 3.8e-08 34.1 0.1 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF1542 PF07564.11 EGO57904.1 - 0.043 13.9 0.2 0.12 12.5 0.2 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) DUF1664 PF07889.12 EGO57904.1 - 1 9.4 5.6 1 9.4 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RRM_1 PF00076.22 EGO57905.1 - 9.1e-09 35.0 0.0 1.8e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sedlin_N PF04628.13 EGO57907.1 - 4.3e-47 159.5 0.0 4.9e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EGO57907.1 - 5.1e-05 23.2 0.2 0.0046 16.9 0.0 2.2 1 1 1 2 2 2 2 Sybindin-like family CENP-T_C PF15511.6 EGO57909.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EGO57909.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EGO57909.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGO57909.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EGO57909.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EGO57909.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGO57909.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EGO57909.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 EGO57909.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region TPR_1 PF00515.28 EGO57910.1 - 2e-34 116.0 20.3 4.3e-06 26.3 0.5 8.9 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 EGO57910.1 - 1.6e-32 109.0 34.6 1.6e-05 24.6 0.4 10.2 11 0 0 11 11 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO57910.1 - 7.9e-28 96.5 29.5 4.8e-21 74.8 1.4 5.4 5 1 2 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EGO57910.1 - 5.1e-24 82.4 24.1 0.0077 16.4 1.2 10.7 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 EGO57910.1 - 1.4e-21 75.3 24.9 0.0085 16.8 0.0 9.9 6 1 4 10 10 9 6 Tetratricopeptide repeat TPR_7 PF13176.6 EGO57910.1 - 2.1e-19 68.0 12.9 0.002 18.0 0.0 8.2 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGO57910.1 - 2.4e-19 69.6 24.4 3.4e-09 37.1 2.3 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGO57910.1 - 6.6e-19 68.0 25.6 8e-08 32.5 0.1 8.0 5 2 5 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 EGO57910.1 - 1.3e-18 66.4 8.5 4e-06 26.4 2.8 7.9 5 1 3 8 8 8 4 TPR repeat TPR_17 PF13431.6 EGO57910.1 - 1.1e-16 60.0 16.8 0.0038 17.5 0.4 9.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGO57910.1 - 4.9e-15 55.9 27.8 6.6e-08 33.1 1.6 7.6 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGO57910.1 - 1.9e-09 37.5 7.8 9.2e-05 22.5 0.2 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGO57910.1 - 7.3e-09 35.7 22.9 0.039 14.6 0.0 9.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_15 PF13429.6 EGO57910.1 - 0.00021 20.6 14.3 0.0078 15.4 1.2 4.4 3 1 2 5 5 5 1 Tetratricopeptide repeat PknG_TPR PF16918.5 EGO57910.1 - 0.0057 15.4 3.5 0.15 10.8 0.1 2.4 1 1 1 2 2 2 1 Protein kinase G tetratricopeptide repeat DUF2225 PF09986.9 EGO57910.1 - 0.013 15.3 2.4 1.5 8.5 0.9 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 EGO57910.1 - 0.018 14.9 20.1 5.3 7.0 0.3 7.6 7 1 1 8 8 8 0 Tetratricopeptide repeat MIT PF04212.18 EGO57910.1 - 0.19 11.8 6.2 41 4.4 0.1 5.2 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 EGO57910.1 - 0.2 12.4 10.5 28 5.7 0.3 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat MAJIN PF15077.6 EGO57910.1 - 0.49 10.1 6.1 0.95 9.2 6.1 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein NARP1 PF12569.8 EGO57910.1 - 1.8 7.3 11.2 3.1 6.6 0.0 3.5 5 0 0 5 5 4 0 NMDA receptor-regulated protein 1 bZIP_2 PF07716.15 EGO57911.1 - 0.011 15.8 4.8 0.011 15.8 4.8 2.8 2 1 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 EGO57911.1 - 0.015 15.3 1.8 0.056 13.5 1.8 1.9 1 0 0 1 1 1 0 bZIP transcription factor NYD-SP28_assoc PF14775.6 EGO57911.1 - 0.062 13.4 2.6 0.12 12.5 1.8 1.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain TSC22 PF01166.18 EGO57911.1 - 0.094 13.0 5.8 0.085 13.2 1.4 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.15 EGO57911.1 - 0.11 12.3 2.7 0.23 11.3 2.7 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.6 EGO57911.1 - 0.12 11.7 10.6 0.21 10.9 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 EGO57911.1 - 2.2 9.0 5.5 0.27 11.9 0.9 1.9 2 0 0 2 2 2 0 Initiation control protein YabA HSP70 PF00012.20 EGO57912.1 - 1.4e-06 26.8 0.0 9.9e-06 24.0 0.0 2.1 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGO57912.1 - 0.034 13.0 0.0 0.079 11.8 0.0 1.5 2 0 0 2 2 2 0 MreB/Mbl protein MMR_HSR1 PF01926.23 EGO57913.1 - 5.1e-10 39.4 0.0 1.4e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGO57913.1 - 3e-09 36.5 0.0 5.4e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 EGO57913.1 - 1.6e-07 30.9 0.0 2.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 EGO57913.1 - 8.2e-07 29.2 2.4 0.025 14.7 0.3 2.6 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EGO57913.1 - 8.6e-06 25.7 0.4 2.6e-05 24.2 0.4 1.8 1 1 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EGO57913.1 - 0.0001 22.6 0.2 0.0038 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 EGO57913.1 - 0.00036 20.0 0.2 0.00071 19.0 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EGO57913.1 - 0.0027 18.2 0.1 0.0077 16.8 0.1 1.9 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 EGO57913.1 - 0.003 17.2 1.3 0.0046 16.7 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGO57913.1 - 0.0077 16.6 0.2 0.015 15.7 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain IIGP PF05049.13 EGO57913.1 - 0.0084 15.2 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.6 EGO57913.1 - 0.013 16.0 0.0 0.029 14.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGO57913.1 - 0.023 13.7 0.7 0.023 13.7 0.7 2.0 2 1 1 3 3 3 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EGO57913.1 - 0.023 14.0 0.2 0.07 12.5 0.2 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 EGO57913.1 - 0.033 14.7 1.6 0.05 14.1 1.4 1.9 1 1 0 1 1 1 0 AAA domain Arf PF00025.21 EGO57913.1 - 0.056 12.9 0.0 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family Cob_adeno_trans PF01923.18 EGO57913.1 - 0.063 13.4 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase AAA_24 PF13479.6 EGO57913.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_P4 PF11602.8 EGO57913.1 - 0.096 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 ATP_bind_1 PF03029.17 EGO57913.1 - 0.1 12.4 0.4 0.44 10.3 0.2 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 EGO57913.1 - 0.22 11.6 2.4 0.35 10.9 0.6 2.2 2 1 1 3 3 3 0 Helicase HerA, central domain TMEM208_SND2 PF05620.11 EGO57914.1 - 2.5e-52 177.1 0.1 2.7e-52 176.9 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF3605 PF12239.8 EGO57915.1 - 1.1e-55 188.2 0.0 1.5e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FAD_binding_6 PF00970.24 EGO57916.1 - 4.6e-31 107.1 0.0 6.7e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGO57916.1 - 2.4e-28 99.0 0.0 3.5e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGO57916.1 - 0.00058 20.0 0.0 0.08 13.1 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EGO57916.1 - 0.18 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Fungal_trans PF04082.18 EGO57917.1 - 1.7e-07 30.5 0.0 5.3e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO57917.1 - 3.5e-05 23.8 5.2 3.5e-05 23.8 5.2 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_7 PF13508.7 EGO57917.1 - 0.00087 19.7 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EGO57917.1 - 0.025 14.6 0.0 0.065 13.2 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_1 PF00583.25 EGO57917.1 - 0.027 14.7 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EGO57917.1 - 0.089 13.5 0.0 0.44 11.2 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGO57917.1 - 0.2 11.6 0.0 0.42 10.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arf PF00025.21 EGO57918.1 - 3.5e-69 231.7 1.2 4e-69 231.6 1.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGO57918.1 - 5.6e-13 48.8 0.0 6.5e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO57918.1 - 5.8e-13 49.1 0.1 8.2e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGO57918.1 - 8.7e-12 44.9 1.5 6e-07 28.9 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGO57918.1 - 1.1e-09 38.1 0.0 1.3e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGO57918.1 - 4e-08 33.3 0.0 5.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGO57918.1 - 5.1e-08 32.5 0.0 6e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGO57918.1 - 6.1e-05 22.7 0.0 0.0017 18.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EGO57918.1 - 0.00079 18.5 0.1 0.0044 16.0 0.1 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 EGO57918.1 - 0.0035 17.3 0.1 0.07 13.1 0.0 2.1 2 0 0 2 2 2 1 NACHT domain FeoB_N PF02421.18 EGO57918.1 - 0.072 12.6 0.3 0.19 11.3 0.3 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.18 EGO57918.1 - 0.076 12.3 0.1 0.15 11.3 0.1 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase DUF4045 PF13254.6 EGO57919.1 - 4.5e-85 286.8 35.3 3e-54 185.3 25.7 7.5 3 2 2 5 5 5 2 Domain of unknown function (DUF4045) Gelsolin PF00626.22 EGO57919.1 - 1.6e-10 40.8 0.0 0.0088 15.9 0.0 3.8 3 0 0 3 3 3 3 Gelsolin repeat DUF3894 PF13033.6 EGO57919.1 - 0.28 11.3 0.2 0.48 10.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3894) Med10 PF09748.9 EGO57920.1 - 6.9e-48 161.6 0.0 1e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex KAR9 PF08580.10 EGO57920.1 - 0.13 10.8 0.8 0.16 10.5 0.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 CHASE3 PF05227.13 EGO57921.1 - 1.6 8.6 7.4 0.47 10.4 0.5 2.8 3 0 0 3 3 3 0 CHASE3 domain bZIP_1 PF00170.21 EGO57923.1 - 1.8e-05 24.7 6.3 1.8e-05 24.7 6.3 2.1 3 0 0 3 3 3 1 bZIP transcription factor ABC_tran_CTD PF16326.5 EGO57923.1 - 0.049 13.9 2.6 6.5 7.1 0.1 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain TMF_TATA_bd PF12325.8 EGO57923.1 - 0.33 11.2 3.3 6.8 7.0 2.9 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Nop53 PF07767.11 EGO57923.1 - 0.52 9.7 16.2 0.044 13.2 11.7 1.4 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Vir_act_alpha_C PF10400.9 EGO57923.1 - 0.69 10.6 3.4 1.9 9.2 3.4 1.7 1 0 0 1 1 1 0 Virulence activator alpha C-term bZIP_2 PF07716.15 EGO57923.1 - 1.6 8.9 10.6 0.95 9.6 7.4 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Stm1_N PF09598.10 EGO57925.1 - 2.5e-13 50.7 3.3 2.5e-13 50.7 3.3 4.3 4 2 1 5 5 5 1 Stm1 HABP4_PAI-RBP1 PF04774.15 EGO57925.1 - 5.1 8.0 28.3 0.15 12.9 18.8 3.0 2 1 1 3 3 3 0 Hyaluronan / mRNA binding family MFS_1 PF07690.16 EGO57926.1 - 6.5e-17 61.5 31.7 3.9e-10 39.2 8.5 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 EGO57926.1 - 0.26 11.1 3.9 0.26 11.0 0.4 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Mtc PF03820.17 EGO57927.1 - 3.3e-119 397.6 0.0 3.7e-119 397.4 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.25 EGO57930.1 - 1e-25 90.6 0.0 1.7e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO57930.1 - 6e-14 51.9 0.0 9.8e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGO57930.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GLE1 PF07817.13 EGO57932.1 - 0.25 10.5 0.0 0.46 9.7 0.0 1.3 1 0 0 1 1 1 0 GLE1-like protein Lactamase_B_4 PF13691.6 EGO57933.1 - 1.5e-25 88.7 0.0 5.3e-25 86.9 0.0 2.0 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EGO57933.1 - 6.8e-11 42.1 0.2 0.00022 20.8 0.0 2.6 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGO57933.1 - 3.6e-05 23.9 0.2 0.00018 21.6 0.1 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Glyco_hydro_16 PF00722.21 EGO57934.1 - 9.3e-07 28.5 0.0 2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Peptidase_C21 PF05381.12 EGO57935.1 - 0.11 12.8 0.2 0.28 11.5 0.2 1.6 1 0 0 1 1 1 0 Tymovirus endopeptidase DEAD PF00270.29 EGO57936.1 - 1.4e-45 155.2 1.0 2e-45 154.7 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO57936.1 - 2.2e-30 105.2 0.1 3.6e-29 101.4 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EGO57936.1 - 0.018 13.9 0.1 0.018 13.9 0.1 3.6 2 1 2 4 4 4 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF2183 PF09949.9 EGO57937.1 - 1.4e-32 111.9 0.0 2.8e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 EGO57937.1 - 0.00035 20.1 0.0 0.00061 19.3 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DUF2120 PF09893.9 EGO57937.1 - 0.039 14.1 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Flavin_Reduct PF01613.18 EGO57938.1 - 2.6e-07 30.8 0.0 3.1e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain PDEase_II PF02112.15 EGO57939.1 - 3.8e-55 187.4 0.0 7.3e-26 91.1 0.0 3.2 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Serglycin PF04360.12 EGO57939.1 - 0.084 12.8 2.1 0.23 11.4 2.1 1.8 1 0 0 1 1 1 0 Serglycin Peptidase_S64 PF08192.11 EGO57939.1 - 3.8 5.9 5.9 5.5 5.4 5.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 AMP-binding PF00501.28 EGO57941.1 - 3.5e-68 230.2 0.0 2.9e-37 128.3 0.0 3.5 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 EGO57941.1 - 7.2e-11 42.9 0.0 2e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 EGO57941.1 - 0.00031 20.7 0.1 0.0008 19.4 0.1 1.6 1 0 0 1 1 1 1 Gas vesicle protein G PX PF00787.24 EGO57943.1 - 2.2e-15 56.6 0.0 3.6e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 PX domain EB1 PF03271.17 EGO57944.1 - 2e-16 59.9 1.0 4.5e-16 58.8 1.0 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EGO57944.1 - 8.2e-06 26.0 0.3 1.5e-05 25.1 0.3 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain HXXSHH PF07586.11 EGO57944.1 - 0.035 13.7 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) CH_2 PF06294.11 EGO57944.1 - 0.05 13.7 0.2 0.084 13.0 0.2 1.3 1 0 0 1 1 1 0 CH-like domain in sperm protein Glyco_transf_8 PF01501.20 EGO57945.1 - 4.5e-14 52.6 0.0 1.8e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EGO57945.1 - 0.0066 15.8 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative K_channel_TID PF07941.11 EGO57947.1 - 0.27 11.7 12.0 0.43 11.1 5.5 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Phage_holin_2_2 PF10746.9 EGO57948.1 - 0.049 13.3 2.6 0.12 12.0 2.6 1.6 1 0 0 1 1 1 0 Phage holin T7 family, holin superfamily II DUF5418 PF17439.2 EGO57948.1 - 1.3 9.1 8.5 4.2 7.5 8.3 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5418) Adeno_E3_CR2 PF02439.15 EGO57950.1 - 8.4e-05 22.2 2.6 0.00016 21.4 2.6 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SARAF PF06682.12 EGO57950.1 - 0.00016 21.5 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis RCR PF12273.8 EGO57950.1 - 0.022 15.4 8.7 0.059 14.0 8.7 1.8 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red CD34_antigen PF06365.12 EGO57950.1 - 0.027 14.1 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 EGO57950.1 - 0.03 15.2 0.0 0.039 14.8 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2615 PF11027.8 EGO57950.1 - 0.064 13.4 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) SKG6 PF08693.10 EGO57950.1 - 0.19 11.2 5.1 0.32 10.5 5.1 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Caskin-Pro-rich PF16907.5 EGO57950.1 - 0.21 12.1 3.2 0.19 12.2 1.8 1.6 2 0 0 2 2 2 0 Proline rich region of Caskin proteins Wzy_C PF04932.15 EGO57950.1 - 0.23 11.1 1.4 0.34 10.5 1.4 1.3 1 0 0 1 1 1 0 O-Antigen ligase DUF4006 PF13179.6 EGO57950.1 - 0.85 9.6 2.9 1.4 8.9 2.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF4006) 7tm_1 PF00001.21 EGO57951.1 - 0.11 11.8 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Vpu PF00558.19 EGO57951.1 - 0.12 12.1 0.5 0.17 11.7 0.5 1.1 1 0 0 1 1 1 0 Vpu protein Shisa PF13908.6 EGO57951.1 - 0.15 12.3 1.4 0.26 11.5 1.4 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator ASFV_J13L PF05568.11 EGO57951.1 - 0.18 11.5 4.2 0.32 10.7 3.6 1.6 1 1 0 1 1 1 0 African swine fever virus J13L protein Asp PF00026.23 EGO57952.1 - 1.1e-36 126.8 0.3 9.7e-32 110.6 0.3 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO57952.1 - 0.00033 21.0 0.4 0.00068 19.9 0.4 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal DUF5489 PF17592.2 EGO57953.1 - 0.13 12.8 3.4 0.09 13.3 2.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5489) DUF2070 PF09843.9 EGO57953.1 - 0.86 7.8 6.4 0.9 7.8 6.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2207 PF09972.9 EGO57953.1 - 1.9 7.1 4.4 2.2 7.0 4.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_C2 PF00648.21 EGO57954.1 - 3.4e-59 200.3 0.2 8.3e-58 195.7 0.2 2.2 1 1 0 1 1 1 1 Calpain family cysteine protease LRR_4 PF12799.7 EGO57955.1 - 1.7 9.2 6.1 1.2 9.7 0.1 3.8 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) EBP PF05241.12 EGO57956.1 - 0.042 13.3 3.7 0.038 13.5 2.8 1.3 1 1 0 1 1 1 0 Emopamil binding protein Dynactin_p62 PF05502.13 EGO57961.1 - 2.6e-209 695.9 0.0 3.5e-209 695.5 0.0 1.1 1 0 0 1 1 1 1 Dynactin p62 family DUF4519 PF15012.6 EGO57961.1 - 0.22 11.7 2.8 0.5 10.6 2.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Ribosomal_S7e PF01251.18 EGO57962.1 - 3.4e-82 274.7 0.1 4e-82 274.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ADH_N PF08240.12 EGO57964.1 - 7.9e-26 90.1 2.6 1.3e-25 89.4 2.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO57964.1 - 1.4e-15 57.4 0.1 5.5e-15 55.5 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGO57964.1 - 1.2e-05 24.8 0.1 2.3e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EGO57964.1 - 0.0026 17.1 0.0 0.0057 16.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Gp_dh_N PF00044.24 EGO57964.1 - 0.064 13.6 0.1 6.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 EGO57964.1 - 0.095 13.8 0.0 0.15 13.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase CTP_synth_N PF06418.14 EGO57965.1 - 2.3e-111 371.3 0.2 3.5e-111 370.7 0.2 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EGO57965.1 - 5.7e-57 192.6 0.0 8.9e-57 191.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGO57965.1 - 2.2e-06 27.6 0.0 5.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 EGO57966.1 - 2.1e-06 27.7 0.0 3.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 EGO57966.1 - 0.083 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_S8 PF00082.22 EGO57967.1 - 4e-38 131.4 0.0 8.3e-38 130.3 0.0 1.5 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EGO57967.1 - 1.9e-19 70.4 0.2 5.5e-19 69.0 0.2 1.8 1 0 0 1 1 1 1 Fn3-like domain FlgD_ig PF13860.6 EGO57967.1 - 1.3e-06 28.2 0.1 4.5e-06 26.4 0.1 1.9 1 0 0 1 1 1 1 FlgD Ig-like domain PA PF02225.22 EGO57967.1 - 3e-06 27.2 0.3 1.5e-05 24.9 0.3 2.3 1 0 0 1 1 1 1 PA domain SpaA PF17802.1 EGO57967.1 - 0.042 14.2 1.1 0.31 11.4 0.5 2.8 2 0 0 2 2 2 0 Prealbumin-like fold domain BolA PF01722.18 EGO57968.1 - 1.7e-09 37.8 0.0 3.7e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein Mucin PF01456.17 EGO57968.1 - 0.012 15.6 0.5 0.016 15.2 0.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2457 PF10446.9 EGO57970.1 - 0.016 14.4 3.7 0.018 14.2 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Myb_DNA-binding PF00249.31 EGO57972.1 - 0.011 15.9 0.3 0.032 14.4 0.3 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain SUIM_assoc PF16619.5 EGO57972.1 - 0.028 14.5 8.8 0.13 12.3 8.8 2.1 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 AT_hook PF02178.19 EGO57972.1 - 5 7.3 10.4 0.1 12.5 2.8 2.3 2 0 0 2 2 2 0 AT hook motif SRI PF08236.11 EGO57973.1 - 2.5e-21 75.6 6.0 8.5e-21 73.9 6.0 2.0 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 EGO57973.1 - 8.9e-18 65.2 0.1 8.9e-18 65.2 0.1 3.9 3 2 0 3 3 3 1 SET domain AWS PF17907.1 EGO57973.1 - 1.7e-12 47.1 10.5 1.7e-12 47.1 10.5 2.5 3 0 0 3 3 3 1 AWS domain WW PF00397.26 EGO57973.1 - 1.1e-05 25.4 1.6 2.5e-05 24.3 1.6 1.7 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 EGO57973.1 - 0.00017 21.5 0.6 0.00049 20.1 0.1 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Nodulin_late PF07127.11 EGO57973.1 - 3.3 8.1 4.9 3.1 8.2 2.1 2.1 2 0 0 2 2 2 0 Late nodulin protein Cullin PF00888.22 EGO57974.1 - 2.8e-166 554.7 0.0 4.2e-166 554.2 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGO57974.1 - 2.9e-25 88.1 0.7 7.1e-25 86.8 0.7 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Nup192 PF11894.8 EGO57975.1 - 0 1521.8 3.1 0 1521.6 3.1 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188 PF10487.9 EGO57975.1 - 8.8e-05 20.6 0.1 0.0066 14.4 0.0 2.5 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 PI3_PI4_kinase PF00454.27 EGO57976.1 - 6.9e-50 170.2 0.0 1.6e-49 169.0 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EGO57976.1 - 3.1e-34 118.3 0.0 3.1e-34 118.3 0.0 3.3 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair FAT PF02259.23 EGO57976.1 - 4.3e-28 98.5 5.2 4.3e-28 98.5 5.2 2.4 3 0 0 3 3 3 1 FAT domain FATC PF02260.20 EGO57976.1 - 1.6e-11 43.8 0.4 5.5e-11 42.1 0.1 2.2 2 0 0 2 2 2 1 FATC domain zf-C3HC4_3 PF13920.6 EGO57977.1 - 1.3e-11 44.2 7.2 2.1e-11 43.5 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO57977.1 - 2.3e-08 33.8 8.5 4.6e-08 32.8 8.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGO57977.1 - 1.2e-07 31.9 9.6 2.6e-07 30.9 9.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO57977.1 - 2e-07 30.7 10.5 2e-07 30.7 10.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO57977.1 - 5.3e-07 29.5 9.3 9.1e-07 28.7 9.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO57977.1 - 3.6e-06 26.7 9.4 3.6e-06 26.7 9.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO57977.1 - 1.4e-05 25.0 4.4 1.4e-05 25.0 4.4 2.7 2 1 1 3 3 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGO57977.1 - 0.0013 18.7 3.5 0.0026 17.8 3.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGO57977.1 - 0.0029 17.4 4.7 0.0062 16.3 4.7 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EGO57977.1 - 0.0093 16.2 5.4 0.021 15.1 5.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGO57977.1 - 0.012 15.8 8.1 0.027 14.7 8.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TerY_C PF15616.6 EGO57977.1 - 0.37 10.9 2.7 0.68 10.1 2.7 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_6 PF14835.6 EGO57977.1 - 0.7 9.8 4.3 1.3 8.9 4.3 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.7 EGO57977.1 - 1.2 9.2 5.4 4.1 7.5 5.4 1.9 1 1 0 1 1 1 0 Double zinc ribbon DNApol_Exo PF18136.1 EGO57978.1 - 6.7e-103 343.7 0.0 1e-102 343.1 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EGO57978.1 - 2.7e-53 181.4 0.0 4.7e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A Mad3_BUB1_I PF08311.12 EGO57978.1 - 0.038 14.0 0.2 0.095 12.7 0.2 1.6 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 DUF1365 PF07103.11 EGO57978.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1365) DNA_pol_A_exo1 PF01612.20 EGO57978.1 - 0.14 11.9 1.3 1.2 8.8 1.3 2.2 1 1 0 1 1 1 0 3'-5' exonuclease CH PF00307.31 EGO57979.1 - 9.8e-13 48.2 0.0 1.6e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGO57979.1 - 0.17 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain DUF1720 PF08226.11 EGO57979.1 - 1.2 9.6 24.3 0.45 11.0 1.0 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1720) NDUFA12 PF05071.16 EGO57980.1 - 1.1e-11 45.4 0.1 1.1e-11 45.4 0.1 3.0 2 1 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Dicty_REP PF05086.12 EGO57980.1 - 4.2 5.2 6.0 5.3 4.9 6.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ndc1_Nup PF09531.10 EGO57980.1 - 6.6 5.3 5.9 9 4.8 5.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HTH_Tnp_4 PF13613.6 EGO57981.1 - 0.0048 16.6 0.3 0.009 15.7 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Vps51 PF08700.11 EGO57982.1 - 3.4e-16 59.1 0.0 1.3e-15 57.2 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 Striatin PF08232.12 EGO57982.1 - 0.015 15.9 8.1 0.015 15.9 8.1 2.3 3 0 0 3 3 3 0 Striatin family DUF3510 PF12022.8 EGO57982.1 - 0.019 15.4 0.8 0.1 13.0 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) DUF913 PF06025.12 EGO57982.1 - 0.2 10.6 1.2 0.48 9.4 1.2 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 EGO57982.1 - 0.23 10.2 5.4 0.4 9.4 5.4 1.2 1 0 0 1 1 1 0 Presenilin PTPRCAP PF15713.5 EGO57982.1 - 2.6 8.3 24.4 0.46 10.8 14.6 2.6 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF2052 PF09747.9 EGO57982.1 - 3.5 7.7 27.3 0.11 12.6 14.7 2.6 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 EGO57982.1 - 6.8 4.9 16.7 0.11 10.7 8.7 1.8 2 0 0 2 2 2 0 CDC45-like protein Glyco_transf_28 PF03033.20 EGO57983.1 - 5.8e-17 62.0 0.1 5.3e-16 58.9 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EGO57983.1 - 2.2e-06 26.7 0.0 4.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase BUD22 PF09073.10 EGO57983.1 - 0.0038 16.7 13.4 0.0038 16.7 13.4 3.3 3 0 0 3 3 3 1 BUD22 Glyco_tran_28_C PF04101.16 EGO57983.1 - 0.082 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Miga PF10265.9 EGO57983.1 - 0.65 8.9 4.9 1.3 7.9 4.9 1.4 1 0 0 1 1 1 0 Mitoguardin Zn_clus PF00172.18 EGO57984.1 - 0.0064 16.6 9.8 0.011 15.8 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain POTRA_3 PF17287.2 EGO57984.1 - 0.19 11.2 1.1 0.49 9.9 1.1 1.6 1 0 0 1 1 1 0 POTRA domain SelP_N PF04592.14 EGO57985.1 - 0.18 11.2 7.7 0.31 10.4 7.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region zf-C2H2 PF00096.26 EGO57987.1 - 0.0019 18.6 5.0 0.17 12.4 0.2 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF753 PF05444.12 EGO57987.1 - 0.041 13.9 2.0 0.079 12.9 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF753) zf-C2H2_4 PF13894.6 EGO57987.1 - 0.28 12.1 8.0 3.8 8.6 0.9 3.4 2 1 0 2 2 2 0 C2H2-type zinc finger Transformer PF06495.11 EGO57987.1 - 5.2 7.1 13.0 1.9 8.6 4.5 2.6 3 0 0 3 3 3 0 Fruit fly transformer protein HeLo PF14479.6 EGO57988.1 - 3.4e-48 164.2 1.4 6.4e-48 163.3 1.4 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 EGO57988.1 - 5.3e-05 22.6 0.0 0.00014 21.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGO57988.1 - 0.00015 21.3 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Zn_clus PF00172.18 EGO57990.1 - 1.2e-08 34.9 4.8 2.5e-08 33.9 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGO57990.1 - 9e-07 28.2 0.1 3e-06 26.5 0.0 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain COesterase PF00135.28 EGO57991.1 - 1.8e-80 271.2 0.0 2.7e-79 267.4 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO57991.1 - 6.6e-12 45.7 0.2 3.3e-11 43.5 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO57991.1 - 0.0024 17.4 0.3 0.0039 16.7 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family NUDIX-like PF09296.11 EGO57992.1 - 5.6e-26 91.2 0.2 2.2e-25 89.3 0.1 2.0 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.28 EGO57992.1 - 3.2e-15 56.3 0.7 1.9e-14 53.8 0.1 2.1 2 0 0 2 2 2 1 NUDIX domain zf-NADH-PPase PF09297.11 EGO57992.1 - 5.6e-09 35.5 1.8 1e-08 34.7 1.8 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DpnI PF06044.12 EGO57992.1 - 0.18 11.4 0.1 0.31 10.6 0.1 1.2 1 0 0 1 1 1 0 Dam-replacing family Ribosomal_L1 PF00687.21 EGO57993.1 - 2.5e-46 158.0 0.1 2.8e-46 157.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Kinetochor_Ybp2 PF08568.10 EGO57994.1 - 3.8e-150 501.4 0.0 4.4e-150 501.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin NPCBM_assoc PF10633.9 EGO57995.1 - 0.036 14.3 0.0 0.04 14.2 0.0 1.1 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase SET PF00856.28 EGO57996.1 - 3e-11 44.0 0.0 1.1e-10 42.1 0.0 2.0 2 1 0 2 2 2 1 SET domain SAF PF08666.12 EGO57996.1 - 0.2 12.3 0.1 11 6.7 0.0 2.4 2 0 0 2 2 2 0 SAF domain MFS_1 PF07690.16 EGO58000.1 - 1.7e-20 73.2 35.5 1.7e-20 73.2 35.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 EGO58000.1 - 1.6e-05 23.7 9.7 1.6e-05 23.7 9.7 3.1 1 1 1 3 3 3 3 MFS/sugar transport protein Peptidase_M56 PF05569.11 EGO58000.1 - 0.24 10.5 0.0 0.53 9.4 0.0 1.5 1 0 0 1 1 1 0 BlaR1 peptidase M56 ECH_1 PF00378.20 EGO58001.1 - 2.1e-20 73.1 0.0 8.6e-20 71.1 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGO58001.1 - 1.1e-13 51.4 0.0 1.2e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PQ-loop PF04193.14 EGO58002.1 - 3.1e-39 132.5 12.0 1.1e-20 73.2 2.7 2.7 2 0 0 2 2 2 2 PQ loop repeat gpUL132 PF11359.8 EGO58002.1 - 0.13 11.8 5.8 0.55 9.7 0.0 2.2 2 0 0 2 2 2 0 Glycoprotein UL132 Sas10 PF09368.10 EGO58003.1 - 2.5e-31 108.0 9.7 2.5e-31 108.0 9.7 3.4 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EGO58003.1 - 2.2e-09 37.8 5.0 4e-09 37.0 0.0 3.4 2 1 0 2 2 2 1 Sas10/Utp3/C1D family adh_short PF00106.25 EGO58004.1 - 1.8e-26 92.8 0.0 2.2e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO58004.1 - 1.6e-16 60.5 0.0 2.1e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO58004.1 - 5.7e-06 26.4 0.0 1.7e-05 24.8 0.1 1.7 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 EGO58004.1 - 0.048 13.0 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 EGO58004.1 - 0.17 11.6 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.6 EGO58004.1 - 0.19 12.2 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF3716 PF12511.8 EGO58005.1 - 4.4e-16 58.7 8.3 7.6e-16 57.9 8.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF1387 PF07139.11 EGO58005.1 - 4.6 6.9 12.2 8.4 6.0 12.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF1771 PF08590.10 EGO58006.1 - 4e-21 75.2 11.3 4e-21 75.2 11.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 EGO58006.1 - 6.2e-12 45.7 0.3 1.7e-11 44.3 0.3 1.8 1 0 0 1 1 1 1 Smr domain DUF4407 PF14362.6 EGO58006.1 - 1.8 7.8 7.3 0.23 10.8 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF5308 PF17233.2 EGO58006.1 - 7.8 6.7 7.3 8 6.7 1.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Methyltransf_23 PF13489.6 EGO58007.1 - 7.8e-15 55.1 0.0 1.2e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO58007.1 - 1.9e-11 44.4 0.0 4.3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO58007.1 - 2.7e-11 44.0 0.0 8.5e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO58007.1 - 5.3e-09 36.7 0.0 3.6e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO58007.1 - 2.1e-08 34.1 0.0 0.0016 18.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 EGO58007.1 - 1.3e-05 24.7 0.0 8.4e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGO58007.1 - 0.0032 17.0 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EGO58007.1 - 0.0063 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.9 EGO58007.1 - 0.011 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 EGO58007.1 - 0.019 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain GidB PF02527.15 EGO58007.1 - 0.049 12.9 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G FtsJ PF01728.19 EGO58007.1 - 0.098 12.8 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 EGO58007.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 EGO58007.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein adh_short PF00106.25 EGO58008.1 - 1.8e-24 86.3 0.3 2.9e-15 56.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO58008.1 - 1.7e-18 67.1 0.3 1.1e-13 51.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EGO58008.1 - 0.057 12.8 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MFS_1 PF07690.16 EGO58009.1 - 1.9e-35 122.5 43.1 1.9e-35 122.5 43.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily COX14 PF14880.6 EGO58009.1 - 0.84 9.5 3.5 0.46 10.4 0.2 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Methyltr_RsmB-F PF01189.17 EGO58011.1 - 2.7e-20 72.9 0.0 1.9e-14 53.8 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F CNDH2_M PF16869.5 EGO58011.1 - 0.0086 16.8 0.1 0.0086 16.8 0.1 2.0 2 0 0 2 2 2 1 PF16858 DUF1996 PF09362.10 EGO58012.1 - 1.5e-64 218.2 0.2 2.3e-64 217.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 EGO58012.1 - 1.5e-17 63.5 10.3 1.5e-17 63.5 10.3 2.3 2 0 0 2 2 2 1 WSC domain Defensin_2 PF01097.18 EGO58012.1 - 0.056 13.4 4.9 0.15 12.0 1.4 2.6 2 0 0 2 2 2 0 Arthropod defensin TPR_11 PF13414.6 EGO58013.1 - 6.3e-16 57.8 2.8 0.0079 15.9 0.0 7.1 6 1 1 7 7 7 4 TPR repeat TPR_16 PF13432.6 EGO58013.1 - 1e-12 48.5 25.6 5.3e-06 27.0 0.1 7.0 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGO58013.1 - 8.8e-12 44.8 22.5 0.031 15.1 0.1 10.2 9 2 2 11 11 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGO58013.1 - 2.7e-11 43.8 23.1 0.016 15.7 0.7 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGO58013.1 - 7.7e-10 38.2 11.3 0.091 12.6 0.1 9.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO58013.1 - 1.2e-09 37.6 16.2 0.26 11.6 0.0 9.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGO58013.1 - 3.2e-07 29.9 26.4 0.46 10.7 0.1 10.1 13 0 0 13 13 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGO58013.1 - 6.8e-06 26.1 9.4 0.41 11.1 0.2 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO58013.1 - 2.5e-05 24.0 7.2 0.17 12.0 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EGO58013.1 - 0.00042 20.8 6.8 1.7 9.1 0.2 4.1 4 0 0 4 4 4 2 Alkyl sulfatase dimerisation DUF4919 PF16266.5 EGO58013.1 - 0.00046 20.2 0.3 0.061 13.3 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4919) ANAPC3 PF12895.7 EGO58013.1 - 0.0019 18.3 9.6 0.33 11.2 0.5 5.0 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGO58013.1 - 0.0061 16.7 15.8 0.97 9.6 0.3 5.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGO58013.1 - 0.0084 16.4 9.0 0.55 10.6 1.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGO58013.1 - 0.62 10.2 2.4 2 8.5 0.0 3.0 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 EGO58013.1 - 1.2 9.5 25.9 3.2 8.1 1.6 7.5 8 2 1 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO58013.1 - 2.7 8.8 10.9 2.2e+02 2.8 0.0 6.0 4 1 0 4 4 3 0 Tetratricopeptide repeat SAM_2 PF07647.17 EGO58014.1 - 2e-09 37.4 0.2 4e-09 36.5 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGO58014.1 - 6.8e-05 23.2 0.3 0.00017 21.9 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 EGO58014.1 - 0.0086 16.2 0.2 0.02 15.0 0.2 1.6 1 0 0 1 1 1 1 IGR protein motif DUF4508 PF14969.6 EGO58014.1 - 0.14 12.5 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) RcnB PF11776.8 EGO58017.1 - 0.1 12.7 1.0 0.1 12.7 1.0 1.6 2 0 0 2 2 2 0 Nickel/cobalt transporter regulator MerR PF00376.23 EGO58017.1 - 1.1 9.1 3.1 6.3 6.7 0.1 2.3 2 0 0 2 2 2 0 MerR family regulatory protein Ribosomal_L29e PF01779.17 EGO58020.1 - 8.1e-23 80.5 8.9 1.2e-22 79.9 8.9 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Mito_carr PF00153.27 EGO58021.1 - 2.8e-56 187.5 2.4 1.9e-18 66.2 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AP2 PF00847.20 EGO58022.1 - 0.14 12.4 0.0 0.64 10.3 0.0 1.8 2 0 0 2 2 2 0 AP2 domain Peptidase_C2 PF00648.21 EGO58023.1 - 4.3e-34 117.9 0.0 6.8e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EGO58023.1 - 8.6e-09 35.8 0.0 1.4e-07 31.9 0.0 2.7 2 1 0 2 2 2 1 Calpain large subunit, domain III Gasdermin PF04598.12 EGO58025.1 - 0.086 12.3 0.9 0.12 11.8 0.9 1.2 1 0 0 1 1 1 0 Gasdermin pore forming domain GEMIN8 PF15348.6 EGO58025.1 - 0.88 9.8 8.3 1.9 8.7 8.3 1.5 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 RNase_P_pop3 PF08228.11 EGO58026.1 - 4.2e-08 33.4 0.0 6.4e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 RNase P subunit Pop3 DUF3517 PF12030.8 EGO58027.1 - 9.1e-105 350.3 0.1 1.8e-104 349.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 EGO58027.1 - 2.6e-40 138.5 2.7 4.7e-40 137.7 1.2 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO58027.1 - 1.2e-20 74.4 1.2 3.7e-20 72.8 1.2 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase fn3_PAP PF17808.1 EGO58028.1 - 0.00023 21.3 0.3 0.00063 19.8 0.3 1.7 1 0 0 1 1 1 1 Fn3-like domain from Purple Acid Phosphatase Rab_eff_C PF04698.12 EGO58028.1 - 1.9 6.6 6.4 3.4 5.8 6.4 1.3 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus ACT_6 PF13740.6 EGO58029.1 - 0.013 15.4 1.9 0.037 14.0 0.1 2.3 2 0 0 2 2 2 0 ACT domain Baculo_PEP_C PF04513.12 EGO58029.1 - 0.024 14.7 9.3 0.077 13.0 9.3 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 EGO58029.1 - 0.44 10.6 5.1 0.9 9.6 4.6 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) GREB1 PF15782.5 EGO58029.1 - 2.5 5.1 7.7 2.8 5.0 7.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CRIM PF16978.5 EGO58031.1 - 2e-48 164.1 0.0 4.6e-48 163.0 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EGO58031.1 - 5.2e-31 107.2 0.0 1.2e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 EGO58031.1 - 0.0011 19.1 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 EGO58031.1 - 0.0028 17.7 0.1 0.0089 16.1 0.1 1.8 1 0 0 1 1 1 1 Raf-like Ras-binding domain PRCC PF10253.9 EGO58032.1 - 1.6e-40 140.2 4.3 1.6e-40 140.2 4.3 2.9 2 1 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting SGL PF08450.12 EGO58033.1 - 6.6e-71 238.8 0.0 8.8e-71 238.3 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 EGO58033.1 - 0.00073 19.4 0.1 0.0026 17.6 0.0 1.9 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Reg_prop PF07494.11 EGO58033.1 - 0.009 16.1 1.8 3.3 8.3 0.0 3.7 4 0 0 4 4 4 1 Two component regulator propeller Arylesterase PF01731.20 EGO58033.1 - 0.024 14.8 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 Arylesterase Lactonase PF10282.9 EGO58033.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller bZIP_2 PF07716.15 EGO58035.1 - 2.7 8.1 14.7 3.2 7.9 13.2 1.8 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 EGO58035.1 - 3.1 8.0 10.2 7.2 6.8 10.2 1.6 1 0 0 1 1 1 0 bZIP transcription factor DUF2834 PF11196.8 EGO58038.1 - 2.3e-06 27.8 2.4 0.0012 19.1 0.6 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2834) Arf PF00025.21 EGO58039.1 - 1.2e-39 135.6 0.0 2e-39 134.9 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGO58039.1 - 6.3e-15 55.2 0.0 1.9e-09 37.1 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGO58039.1 - 8.4e-10 38.4 0.0 9.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EGO58039.1 - 6.3e-09 36.1 0.0 1.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGO58039.1 - 6.6e-09 35.6 0.0 2.3e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 EGO58039.1 - 3.9e-07 29.7 0.0 8.6e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGO58039.1 - 0.00025 20.7 0.1 0.0011 18.6 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGO58039.1 - 0.00044 20.3 0.0 0.00068 19.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNase_PH PF01138.21 EGO58040.1 - 3.1e-23 82.7 0.0 4.8e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGO58040.1 - 1.4e-06 28.2 0.0 2.9e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.12 EGO58041.1 - 1.6e-85 286.8 28.9 2.4e-85 286.2 28.9 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein AF-4 PF05110.13 EGO58041.1 - 0.032 12.3 11.7 0.041 12.0 11.7 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SDA1 PF05285.12 EGO58041.1 - 0.043 13.2 30.7 0.055 12.9 30.7 1.3 1 0 0 1 1 1 0 SDA1 MRPL52 PF18699.1 EGO58041.1 - 0.1 12.8 0.1 0.1 12.8 0.1 3.4 3 1 1 4 4 2 0 Mitoribosomal protein mL52 CDC45 PF02724.14 EGO58041.1 - 0.11 10.7 28.3 0.15 10.3 28.3 1.3 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 EGO58041.1 - 0.28 10.9 17.4 0.41 10.3 17.4 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) GEMIN8 PF15348.6 EGO58041.1 - 1.1 9.5 14.7 1.7 8.9 14.7 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Nop14 PF04147.12 EGO58041.1 - 1.7 6.7 39.2 2.1 6.4 39.2 1.0 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 EGO58041.1 - 2.1 7.3 15.6 2.4 7.1 15.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Apt1 PF10351.9 EGO58041.1 - 2.4 6.9 17.3 3.1 6.5 17.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PA26 PF04636.13 EGO58041.1 - 2.7 6.8 6.2 3.4 6.5 6.2 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Presenilin PF01080.17 EGO58041.1 - 4.7 5.9 13.2 6.1 5.5 13.2 1.2 1 0 0 1 1 1 0 Presenilin BP28CT PF08146.12 EGO58042.1 - 1.3e-42 145.3 1.2 2.7e-41 141.1 0.2 3.2 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EGO58042.1 - 2.7e-26 92.2 0.1 2.7e-26 92.2 0.1 5.4 6 1 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 EGO58042.1 - 8.6e-05 22.9 20.2 0.12 12.8 0.9 6.9 7 1 0 7 7 7 3 HEAT repeats HEAT PF02985.22 EGO58042.1 - 0.00017 21.6 9.1 0.27 11.6 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat CBF PF03914.17 EGO58043.1 - 1.8e-26 93.2 0.1 1.8e-26 93.2 0.1 2.6 2 1 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.11 EGO58043.1 - 8.8e-26 90.2 0.3 8.8e-26 90.2 0.3 2.3 2 0 0 2 2 2 1 Nucleolar complex-associated protein LepA_C PF06421.12 EGO58043.1 - 2.5 8.3 6.5 41 4.4 2.2 3.2 2 1 0 2 2 2 0 GTP-binding protein LepA C-terminus Asp PF00026.23 EGO58044.1 - 2.7e-65 220.8 0.8 3.8e-65 220.4 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO58044.1 - 2.3e-15 57.3 0.4 5.2e-13 49.6 1.0 3.4 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO58044.1 - 3.9e-07 30.6 0.2 0.75 10.5 0.0 3.5 3 0 0 3 3 3 3 Aspartyl protease gag-asp_proteas PF13975.6 EGO58044.1 - 0.0018 18.8 0.0 1.6 9.3 0.0 3.4 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease CFEM PF05730.11 EGO58045.1 - 0.0019 18.3 9.0 0.0035 17.4 9.0 1.4 1 0 0 1 1 1 1 CFEM domain STE PF02200.16 EGO58046.1 - 3.1e-56 188.5 0.1 5.4e-56 187.7 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 EGO58046.1 - 1.6e-11 43.9 11.4 6.4e-06 26.3 1.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO58046.1 - 7.8e-08 32.5 9.5 0.002 18.8 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGO58046.1 - 8e-08 32.4 3.1 8e-08 32.4 3.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EGO58046.1 - 0.0007 19.5 1.0 0.0007 19.5 1.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGO58046.1 - 0.0049 17.1 1.6 0.16 12.3 0.6 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 EGO58046.1 - 0.41 11.1 2.4 2.6 8.6 0.2 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-Di19 PF05605.12 EGO58046.1 - 0.52 10.6 3.1 0.95 9.8 3.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 EGO58046.1 - 0.57 10.3 3.4 2.1 8.5 3.5 2.0 1 1 1 2 2 2 0 BED zinc finger zf-TRAF PF02176.18 EGO58046.1 - 0.77 10.5 3.4 1.5 9.5 3.4 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger Zn_clus PF00172.18 EGO58048.1 - 1.1e-06 28.7 9.3 2e-06 27.8 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT PF02985.22 EGO58049.1 - 3.8e-05 23.6 0.4 0.0089 16.2 0.1 4.2 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 EGO58049.1 - 0.0023 18.3 0.5 1.9 9.0 0.0 4.5 5 0 0 5 5 5 1 HEAT repeats RTP1_C1 PF10363.9 EGO58049.1 - 0.03 14.5 0.0 0.44 10.7 0.0 2.8 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 EBP PF05241.12 EGO58050.1 - 1.2e-47 161.6 5.9 1.7e-47 161.1 5.9 1.2 1 0 0 1 1 1 1 Emopamil binding protein TAF4 PF05236.14 EGO58051.1 - 0.001 18.9 8.6 0.0017 18.1 8.6 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TFIIF_alpha PF05793.12 EGO58051.1 - 0.021 13.4 16.0 0.032 12.8 16.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pex26 PF07163.12 EGO58051.1 - 0.022 14.1 0.9 0.044 13.1 0.9 1.4 1 0 0 1 1 1 0 Pex26 protein Macoilin PF09726.9 EGO58051.1 - 0.1 11.1 2.3 0.24 9.9 2.3 1.6 1 0 0 1 1 1 0 Macoilin family DUF572 PF04502.13 EGO58051.1 - 0.3 10.7 10.7 0.47 10.0 10.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3381 PF11861.8 EGO58051.1 - 1.9 8.2 14.1 3.4 7.4 14.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Activator_LAG-3 PF11498.8 EGO58051.1 - 4.2 6.2 5.3 6.7 5.6 5.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HCMV_UL139 PF12507.8 EGO58051.1 - 8.1 6.8 10.7 2.3 8.6 1.9 2.4 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein SRP-alpha_N PF04086.13 EGO58051.1 - 8.9 6.1 19.2 15 5.4 19.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PHF5 PF03660.14 EGO58052.1 - 4.9e-52 174.5 10.5 5.5e-52 174.3 10.5 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EGO58052.1 - 0.68 7.7 7.7 0.71 7.7 7.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EGO58052.1 - 4 7.5 16.3 7 6.8 2.3 3.0 1 1 1 2 2 2 0 Double zinc ribbon Pinin_SDK_memA PF04696.13 EGO58053.1 - 1.2e-31 109.5 15.6 1.2e-31 109.5 15.6 2.5 2 1 1 3 3 3 1 pinin/SDK/memA/ protein conserved region Abhydrolase_1 PF00561.20 EGO58054.1 - 3.5e-19 69.5 0.0 3.4e-18 66.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO58054.1 - 9.5e-18 65.6 0.1 1.7e-17 64.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO58054.1 - 4.7e-12 45.7 0.0 1.1e-11 44.5 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EGO58054.1 - 0.0075 16.4 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Cript PF10235.9 EGO58055.1 - 5.1e-19 68.6 14.1 5.1e-19 68.6 14.1 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT CTX_RstB PF07459.11 EGO58055.1 - 0.064 13.5 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 CTX phage RstB protein zf-C3HC4_3 PF13920.6 EGO58055.1 - 0.31 10.9 14.1 3.3 7.6 9.2 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2039 PF10217.9 EGO58055.1 - 0.39 11.1 14.5 0.099 13.0 7.8 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) NUDE_C PF04880.13 EGO58055.1 - 0.89 10.0 6.5 1 9.8 6.5 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DZR PF12773.7 EGO58055.1 - 4 7.6 18.6 19 5.4 13.1 2.9 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 EGO58055.1 - 4.1 6.9 15.8 4.6 6.8 0.5 3.3 2 1 1 3 3 3 0 zinc-ribbon domain PhoLip_ATPase_C PF16212.5 EGO58056.1 - 1.5e-81 273.8 12.0 1.5e-81 273.8 12.0 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGO58056.1 - 1.8e-26 91.6 5.0 4.6e-26 90.3 5.0 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGO58056.1 - 9e-12 45.7 2.4 5.9e-07 30.0 0.4 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGO58056.1 - 3e-11 43.2 0.0 1.6e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGO58056.1 - 4.2e-08 32.9 0.0 9.9e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGO58056.1 - 0.00069 19.4 0.5 0.0049 16.7 0.5 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Catalase PF00199.19 EGO58058.1 - 8.3e-165 548.5 0.1 1e-164 548.2 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 EGO58058.1 - 7.5e-49 165.3 1.1 1.2e-48 164.6 1.1 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 EGO58058.1 - 2.8e-20 72.3 0.2 6.5e-20 71.1 0.2 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Nucleoside_tran PF01733.18 EGO58059.1 - 1.7e-31 109.8 6.1 1.7e-31 109.8 6.1 2.8 2 1 0 2 2 2 1 Nucleoside transporter Ins_P5_2-kin PF06090.12 EGO58061.1 - 5.1e-47 160.9 0.0 9.7e-47 160.0 0.0 1.4 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Exop_C PF18559.1 EGO58061.1 - 0.12 12.3 0.1 1.2 9.0 0.0 2.4 3 0 0 3 3 3 0 Galactose-binding domain-like YEATS PF03366.16 EGO58062.1 - 2.1e-24 85.3 0.5 2.7e-24 85.0 0.5 1.1 1 0 0 1 1 1 1 YEATS family DarA_C PF18789.1 EGO58062.1 - 0.076 13.3 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Defence against restriction A C-terminal Epimerase PF01370.21 EGO58063.1 - 4e-06 26.5 0.0 6.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGO58063.1 - 1.4e-05 25.1 0.0 6.9e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGO58063.1 - 0.00059 19.1 0.0 0.0052 16.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EGO58063.1 - 0.0044 16.1 0.0 0.01 14.9 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGO58063.1 - 0.15 11.1 0.0 0.35 9.9 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain 3HCDH_N PF02737.18 EGO58063.1 - 0.17 11.7 0.0 7.9 6.3 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TcdA_TcdB_pore PF12920.7 EGO58064.1 - 0.052 11.8 0.0 0.077 11.2 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain SR-25 PF10500.9 EGO58065.1 - 0.25 10.9 29.6 0.26 10.8 29.6 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Eapp_C PF10238.9 EGO58065.1 - 1.2 9.2 7.8 1.3 9.1 7.8 1.0 1 0 0 1 1 1 0 E2F-associated phosphoprotein Sec62 PF03839.16 EGO58065.1 - 1.2 8.5 10.6 1.4 8.4 10.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Connexin PF00029.19 EGO58065.1 - 1.7 8.4 7.6 1.7 8.4 7.6 1.0 1 0 0 1 1 1 0 Connexin DUF3807 PF12720.7 EGO58065.1 - 2 8.7 12.9 2 8.6 12.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DDE_Tnp_IS1595 PF12762.7 EGO58065.1 - 2 8.4 8.8 2.1 8.4 8.8 1.1 1 0 0 1 1 1 0 ISXO2-like transposase domain DUF3464 PF11947.8 EGO58065.1 - 2.1 8.1 11.3 2.1 8.1 11.3 1.0 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CCDC106 PF15794.5 EGO58065.1 - 2.3 7.9 15.7 2.4 7.8 15.7 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Folate_carrier PF01770.18 EGO58065.1 - 2.6 6.7 3.1 2.6 6.7 3.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier AP3D1 PF06375.11 EGO58065.1 - 2.7 8.2 23.9 3.9 7.7 23.9 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Peptidase_S49_N PF08496.10 EGO58065.1 - 5 7.2 18.2 5.3 7.1 18.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1387 PF07139.11 EGO58065.1 - 6.1 6.5 21.3 7.8 6.1 21.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) ORC5_C PF14630.6 EGO58065.1 - 7.3 6.0 11.2 6.7 6.1 11.2 1.0 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Coilin_N PF15862.5 EGO58065.1 - 9.6 6.0 17.5 11 5.9 17.5 1.1 1 0 0 1 1 1 0 Coilin N-terminus Kelch_5 PF13854.6 EGO58066.1 - 2.7e-13 49.6 10.9 4.8e-11 42.4 0.5 5.8 6 0 0 6 6 6 1 Kelch motif Kelch_6 PF13964.6 EGO58066.1 - 1.6e-06 28.2 11.8 0.55 10.6 0.1 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EGO58066.1 - 0.00067 19.5 4.2 19 5.4 0.0 5.6 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.6 EGO58066.1 - 0.00086 19.3 11.4 0.059 13.4 0.1 5.3 5 1 0 5 5 5 2 Galactose oxidase, central domain VSP PF03302.13 EGO58066.1 - 0.018 13.9 0.8 0.027 13.3 0.8 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Kelch_1 PF01344.25 EGO58066.1 - 0.052 13.1 5.6 3.3 7.4 0.1 4.7 6 0 0 6 6 6 0 Kelch motif Phage_holin_2_4 PF16082.5 EGO58066.1 - 0.053 13.3 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Flg_new PF09479.10 EGO58066.1 - 0.079 13.1 0.1 0.29 11.4 0.1 2.0 1 0 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) Kelch_3 PF13415.6 EGO58066.1 - 0.63 10.4 8.1 29 5.1 0.0 5.4 6 0 0 6 6 6 0 Galactose oxidase, central domain DUF1749 PF08538.10 EGO58067.1 - 1.4e-119 398.6 0.0 1.6e-119 398.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 EGO58067.1 - 1.5e-06 29.0 0.0 2.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EGO58067.1 - 0.026 14.4 0.0 5.4 6.7 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EGO58067.1 - 0.054 12.8 0.0 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF1057 PF06342.12 EGO58067.1 - 0.1 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) p450 PF00067.22 EGO58069.1 - 1.1e-48 166.2 0.0 1.5e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 eIF-5_eIF-2B PF01873.17 EGO58070.1 - 4.6e-39 132.9 0.0 8.8e-39 132.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EGO58070.1 - 1.5e-22 79.5 3.2 1.5e-22 79.5 3.2 2.7 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Zn-ribbon_8 PF09723.10 EGO58070.1 - 0.018 15.2 1.1 0.043 13.9 1.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain CoaE PF01121.20 EGO58073.1 - 5.7e-41 140.1 0.0 2.8e-40 137.9 0.0 1.9 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EGO58073.1 - 0.023 15.2 0.5 0.24 11.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain CcmH PF03918.14 EGO58073.1 - 0.15 11.3 0.6 0.28 10.5 0.6 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Tim17 PF02466.19 EGO58075.1 - 6.3e-25 87.7 3.5 9.1e-25 87.2 3.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family LCE6A PF15858.5 EGO58075.1 - 0.19 12.5 3.4 0.32 11.8 3.4 1.3 1 0 0 1 1 1 0 Late cornified envelope protein 6A family DUF2428 PF10350.9 EGO58076.1 - 6.3e-61 206.0 0.1 2.1e-60 204.3 0.0 2.0 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 EGO58076.1 - 5.8e-06 26.1 11.6 2 8.9 0.0 7.7 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 EGO58076.1 - 0.0023 18.3 7.6 2.4 8.6 0.6 5.8 6 0 0 6 6 6 1 HEAT repeats HEAT_EZ PF13513.6 EGO58076.1 - 6 7.5 7.0 49 4.6 0.2 4.8 5 0 0 5 5 5 0 HEAT-like repeat Gtr1_RagA PF04670.12 EGO58080.1 - 3.2e-52 177.2 0.2 4.5e-52 176.7 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region LMBR1 PF04791.16 EGO58081.1 - 5.2e-114 382.0 2.9 5.9e-114 381.8 2.9 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Phage_P2_GpE PF06528.12 EGO58081.1 - 0.16 11.6 0.1 0.46 10.1 0.1 1.8 1 0 0 1 1 1 0 Phage P2 GpE Aldedh PF00171.22 EGO58082.1 - 7.3e-184 611.6 0.4 8.2e-184 611.4 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGO58082.1 - 7.9e-05 22.2 0.0 0.022 14.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Adenosine_kin PF04008.14 EGO58082.1 - 0.12 12.2 0.1 6 6.6 0.1 2.5 2 0 0 2 2 2 0 Adenosine specific kinase MIF PF01187.18 EGO58084.1 - 1.3e-05 25.5 0.0 2.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DUF3336 PF11815.8 EGO58085.1 - 1.3e-54 183.7 1.2 2e-54 183.1 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EGO58085.1 - 2.1e-18 67.2 0.0 2.2e-17 63.9 0.0 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase Arf PF00025.21 EGO58086.1 - 1.7e-65 219.8 0.0 1.8e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGO58086.1 - 3e-11 43.1 0.0 6.2e-08 32.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EGO58086.1 - 2.7e-08 34.1 0.0 1.4e-07 31.8 0.0 2.1 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGO58086.1 - 6.9e-08 32.1 0.0 8.8e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGO58086.1 - 2e-07 31.1 0.0 2.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EGO58086.1 - 2.3e-07 30.6 0.0 3.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGO58086.1 - 3.7e-06 26.4 0.0 4.2e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGO58086.1 - 0.0035 16.9 0.1 0.08 12.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_25 PF13481.6 EGO58086.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cementoin PF10511.9 EGO58086.1 - 0.22 11.9 0.1 0.44 10.9 0.1 1.4 1 0 0 1 1 1 0 Trappin protein transglutaminase binding domain DUF2457 PF10446.9 EGO58088.1 - 9.6e-170 565.7 26.9 9.6e-170 565.7 26.9 2.9 2 1 2 4 4 4 1 Protein of unknown function (DUF2457) TFIIA PF03153.13 EGO58088.1 - 0.00075 19.6 12.0 0.0018 18.4 12.0 1.6 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 EGO58088.1 - 7.9 4.6 22.2 1.9 6.7 16.2 2.1 2 0 0 2 2 2 0 CDC45-like protein ATP-synt_DE_N PF02823.16 EGO58091.1 - 1.5e-16 60.1 0.1 2.5e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Steroid_dh PF02544.16 EGO58093.1 - 1.3e-10 41.4 2.4 2.9e-10 40.3 2.4 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EGO58093.1 - 8.5e-05 22.2 1.1 0.00017 21.2 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ank_2 PF12796.7 EGO58094.1 - 7.3e-22 77.8 0.1 2.1e-14 53.9 0.1 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO58094.1 - 3.8e-12 46.5 0.0 9.5e-07 29.3 0.0 4.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO58094.1 - 2.3e-11 42.9 0.1 0.0017 18.6 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EGO58094.1 - 5.5e-11 42.5 0.3 7.9e-06 26.1 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGO58094.1 - 1.1e-10 41.5 0.3 0.0031 17.9 0.2 4.6 4 0 0 4 4 4 3 Ankyrin repeat MMR_HSR1_Xtn PF16897.5 EGO58095.1 - 1.3e-41 140.9 1.8 9.4e-41 138.1 0.5 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EGO58095.1 - 2.4e-23 81.9 0.2 4.7e-23 81.0 0.2 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EGO58095.1 - 2e-21 76.2 0.0 1.3e-20 73.6 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO58095.1 - 1.1e-09 38.0 0.1 5.2e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGO58095.1 - 0.00017 21.7 0.1 0.045 13.8 0.0 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 EGO58095.1 - 0.00022 20.8 0.1 3.7 7.0 0.0 3.8 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 EGO58095.1 - 0.0064 15.5 0.3 0.026 13.5 0.1 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 EGO58095.1 - 0.035 13.4 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 AIG1 family RsgA_GTPase PF03193.16 EGO58095.1 - 0.045 13.7 0.1 5.6 6.9 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 EGO58095.1 - 0.053 13.7 0.0 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO58095.1 - 0.063 12.7 0.1 11 5.5 0.1 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.6 EGO58095.1 - 0.064 13.5 0.0 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain HTH_Tnp_Tc5 PF03221.16 EGO58100.1 - 8.2e-12 45.0 0.0 3.6e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EGO58100.1 - 0.00014 21.4 0.0 0.00061 19.4 0.0 2.0 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 EGO58100.1 - 0.021 14.8 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 MarR family HTH_Tnp_4 PF13613.6 EGO58100.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_38 PF13936.6 EGO58100.1 - 0.11 12.2 0.1 0.52 10.1 0.0 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain PXA PF02194.15 EGO58102.1 - 1.2e-50 172.0 1.2 1.9e-50 171.4 1.2 1.3 1 0 0 1 1 1 1 PXA domain zf-Mss51 PF13824.6 EGO58103.1 - 2.7e-29 101.0 8.2 5.2e-29 100.1 8.2 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 EGO58103.1 - 0.0086 16.1 0.9 0.0086 16.1 0.9 2.2 2 0 0 2 2 2 1 MYND finger Peptidase_M35 PF02102.15 EGO58103.1 - 6.5 5.5 6.3 9.9 4.9 6.3 1.1 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family MMS1_N PF10433.9 EGO58104.1 - 8.6e-142 473.2 0.0 6.1e-140 467.1 0.0 2.9 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGO58104.1 - 3.6e-104 348.6 0.0 7.7e-103 344.2 0.0 2.8 3 0 0 3 3 3 1 CPSF A subunit region Lipase_GDSL_2 PF13472.6 EGO58105.1 - 6e-21 75.6 0.0 9.4e-21 75.0 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGO58105.1 - 8e-18 65.1 0.0 9.6e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF3305 PF11749.8 EGO58105.1 - 0.033 14.3 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3305) DUF919 PF06034.11 EGO58106.1 - 0.045 13.6 0.5 0.079 12.8 0.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Methyltransf_23 PF13489.6 EGO58110.1 - 4.1e-15 56.0 0.0 1.8e-14 53.9 0.0 2.0 1 1 2 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO58110.1 - 1.9e-09 38.1 0.0 5.1e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO58110.1 - 9.5e-08 32.7 0.0 2.5e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO58110.1 - 1.4e-06 28.8 0.0 6.1e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO58110.1 - 1.9e-06 27.8 0.0 6.9e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGO58110.1 - 0.0016 17.9 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 EGO58110.1 - 0.0031 16.9 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 EGO58110.1 - 0.004 17.3 0.0 0.086 13.0 0.0 2.7 3 0 0 3 3 3 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EGO58110.1 - 0.016 14.5 0.0 0.044 13.1 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EGO58110.1 - 0.044 13.1 0.0 0.089 12.1 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 EGO58110.1 - 0.066 12.8 0.0 0.58 9.7 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase small domain GDP_Man_Dehyd PF16363.5 EGO58112.1 - 2.2e-56 191.7 0.0 2.7e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGO58112.1 - 1.1e-52 178.9 0.0 1.4e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGO58112.1 - 1.9e-19 69.9 0.0 2.5e-18 66.2 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGO58112.1 - 1.2e-16 60.7 0.0 1.5e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGO58112.1 - 3.1e-16 59.3 0.0 4.3e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EGO58112.1 - 2.9e-14 52.8 0.0 3.7e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EGO58112.1 - 1.5e-07 31.5 0.0 2.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Brix PF04427.18 EGO58113.1 - 3.3e-17 63.2 0.0 6.2e-17 62.3 0.0 1.5 1 1 0 1 1 1 1 Brix domain Sporozoite_P67 PF05642.11 EGO58113.1 - 0.32 9.0 3.8 0.48 8.4 3.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Na_trans_assoc PF06512.13 EGO58113.1 - 0.53 10.5 10.8 0.82 9.9 10.8 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated BUD22 PF09073.10 EGO58113.1 - 1.3 8.3 20.2 1.9 7.7 20.2 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 EGO58113.1 - 6.3 5.2 7.5 9.3 4.7 7.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HGTP_anticodon PF03129.20 EGO58114.1 - 9.4e-22 77.0 1.7 4.4e-21 74.8 0.0 2.7 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGO58114.1 - 8.1e-07 29.2 0.0 3.5e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Semialdhyde_dh PF01118.24 EGO58114.1 - 0.081 13.4 0.2 0.28 11.6 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGO58114.1 - 0.13 12.8 0.1 0.35 11.5 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.25 EGO58115.1 - 9e-70 235.0 0.0 1.5e-69 234.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO58115.1 - 3.4e-54 183.9 0.0 5.7e-54 183.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EGO58115.1 - 5.3e-24 84.4 0.0 1.6e-23 82.8 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 EGO58115.1 - 7.5e-07 28.8 0.0 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGO58115.1 - 5.2e-06 25.5 0.0 5.2e-06 25.5 0.0 2.3 2 1 0 2 2 1 1 Fungal protein kinase PH_11 PF15413.6 EGO58115.1 - 9.4e-06 26.0 0.2 3e-05 24.4 0.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EGO58115.1 - 0.02 15.4 0.1 0.046 14.2 0.1 1.7 1 0 0 1 1 1 0 PH domain Haspin_kinase PF12330.8 EGO58115.1 - 0.031 13.2 0.6 0.06 12.3 0.6 1.6 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EGO58115.1 - 0.039 13.9 0.2 0.039 13.9 0.2 2.8 3 1 1 4 4 4 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGO58115.1 - 0.071 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EGO58115.1 - 0.08 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KIND PF16474.5 EGO58115.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Haspin_kinase PF12330.8 EGO58116.1 - 3.4e-33 115.1 0.0 1.3e-32 113.2 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain XkdW PF09636.10 EGO58116.1 - 0.13 12.3 0.2 0.44 10.6 0.2 1.9 1 0 0 1 1 1 0 XkdW protein Trypan_PARP PF05887.11 EGO58116.1 - 1.6 8.7 8.5 4.3 7.3 8.5 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FYDLN_acid PF09538.10 EGO58116.1 - 3.6 8.3 5.5 22 5.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) CHORD PF04968.12 EGO58118.1 - 0.009 16.7 1.0 0.009 16.7 1.0 2.9 3 1 0 3 3 3 1 CHORD PDT PF00800.18 EGO58119.1 - 2.8e-50 170.7 0.0 3.7e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 EGO58119.1 - 5.3e-05 22.9 0.0 0.00023 20.8 0.0 2.1 2 0 0 2 2 2 1 ACT domain eRF1_2 PF03464.15 EGO58120.1 - 8.9e-45 152.3 0.0 1.5e-44 151.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EGO58120.1 - 6.3e-41 139.4 0.6 1.2e-40 138.5 0.6 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EGO58120.1 - 7.5e-22 77.7 0.0 1.2e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EGO58120.1 - 6e-12 46.0 0.1 2.5e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EGO58120.1 - 4.2e-10 40.0 0.0 7.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF1770 PF08589.10 EGO58121.1 - 4.5e-26 91.7 8.4 6.8e-26 91.1 8.4 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.6 EGO58122.1 - 4.5e-07 29.3 0.0 9.2e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 SDA1 PF05285.12 EGO58122.1 - 0.17 11.3 20.2 0.34 10.3 20.2 1.4 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EGO58122.1 - 0.46 9.8 23.6 0.044 13.1 16.9 2.1 2 0 0 2 2 2 0 BUD22 Astro_capsid_p PF12226.8 EGO58122.1 - 0.63 9.1 17.1 1.1 8.4 17.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TFIIA PF03153.13 EGO58122.1 - 0.73 9.8 17.7 1.3 8.9 17.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 EGO58122.1 - 4.2 6.9 19.2 8.1 5.9 19.2 1.5 1 0 0 1 1 1 0 PPP4R2 Ribosomal_L2_C PF03947.18 EGO58123.1 - 2.3e-41 140.9 5.9 2.3e-41 140.9 5.9 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGO58123.1 - 2.6e-16 59.3 0.1 6.2e-16 58.1 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.24 EGO58124.1 - 3.5e-67 226.9 0.0 4.1e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EGO58124.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.9 EGO58126.1 - 2.5e-47 161.7 0.1 4e-47 161.0 0.1 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EGO58126.1 - 2.6e-20 73.5 0.2 8.3e-20 71.8 0.1 2.0 2 0 0 2 2 2 1 Telomerase activating protein Est1 zf-C2H2 PF00096.26 EGO58127.1 - 0.59 10.7 13.0 0.42 11.2 0.7 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Velvet PF11754.8 EGO58127.1 - 1.4 8.8 10.0 6.8 6.5 10.0 1.9 1 1 0 1 1 1 0 Velvet factor DUF629 PF04780.12 EGO58127.1 - 2.4 6.6 5.2 1.9 6.9 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) G10 PF01125.17 EGO58128.1 - 6.3e-63 210.9 4.2 6.9e-63 210.8 4.2 1.0 1 0 0 1 1 1 1 G10 protein Complex1_LYR PF05347.15 EGO58129.1 - 2.2e-08 34.0 0.1 5.4e-08 32.8 0.1 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGO58129.1 - 1.7e-07 31.9 0.1 2.3e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like RMMBL PF07521.12 EGO58129.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain CAP_N PF01213.19 EGO58131.1 - 7.2 6.0 9.0 5.5 6.4 7.3 1.5 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SNF5 PF04855.12 EGO58133.1 - 2.5e-64 217.3 1.0 1.9e-63 214.5 1.0 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.24 EGO58134.1 - 2e-06 27.6 0.0 4.5e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 PHD PF00628.29 EGO58135.1 - 9.3e-15 54.3 18.3 1.1e-09 38.0 7.7 2.4 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 EGO58135.1 - 0.022 15.0 5.7 0.08 13.2 2.3 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain Zf_RING PF16744.5 EGO58135.1 - 0.045 13.9 7.3 0.45 10.7 0.1 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger PHD_2 PF13831.6 EGO58135.1 - 0.099 12.2 9.1 0.26 10.9 3.0 2.8 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 EGO58135.1 - 0.4 10.6 12.4 0.65 9.9 0.2 2.7 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 EGO58135.1 - 0.49 10.0 16.6 0.13 11.9 3.7 3.6 4 0 0 4 4 4 0 PHD/FYVE-zinc-finger like domain HBS1_N PF08938.10 EGO58135.1 - 6.8 7.1 6.7 31 4.9 0.0 3.3 4 0 0 4 4 4 0 HBS1 N-terminus HEAT PF02985.22 EGO58136.1 - 1.4e-07 31.2 0.8 0.64 10.4 0.0 5.4 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 EGO58136.1 - 2.1e-05 24.8 0.9 0.0037 17.6 0.1 4.1 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 EGO58136.1 - 0.014 15.9 0.8 5.2 7.7 0.0 4.4 3 0 0 3 3 3 0 HEAT-like repeat Cnd1 PF12717.7 EGO58136.1 - 0.062 13.3 7.9 6 6.9 0.0 5.6 6 1 0 7 7 7 0 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.12 EGO58136.1 - 0.11 12.5 0.3 1.7 8.7 0.0 3.2 3 1 1 4 4 4 0 Exportin 1-like protein Lactamase_B PF00753.27 EGO58138.1 - 1.1e-07 32.0 0.1 2e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGO58138.1 - 0.00016 21.3 0.4 0.0024 17.4 0.4 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.12 EGO58138.1 - 0.14 12.1 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain YjeF_N PF03853.15 EGO58139.1 - 1.2e-41 142.5 0.0 1.8e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EGO58139.1 - 6.9e-19 68.7 0.2 6.9e-19 68.7 0.2 2.5 2 0 0 2 2 2 1 FDF domain Nha1_C PF08619.10 EGO58142.1 - 3.8e-133 445.1 51.5 1.5e-132 443.2 51.5 1.7 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 EGO58142.1 - 9e-78 261.7 22.6 1.1e-77 261.4 22.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Colicin_E5 PF12106.8 EGO58142.1 - 9.2e-05 22.7 0.5 0.038 14.3 0.0 2.6 2 0 0 2 2 2 2 Colicin E5 ribonuclease domain YrhC PF14143.6 EGO58142.1 - 0.53 10.4 2.7 0.79 9.8 0.6 2.3 2 0 0 2 2 2 0 YrhC-like protein PRP4 PF08799.11 EGO58142.1 - 7.3 6.2 9.4 17 5.1 2.2 2.7 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like Tom22 PF04281.13 EGO58143.1 - 1.7e-45 154.2 0.1 2e-45 154.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Formyl_trans_C PF02911.18 EGO58144.1 - 0.19 12.0 0.0 6.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain PP2C PF00481.21 EGO58145.1 - 1.5e-61 208.3 0.8 1.1e-50 172.7 0.1 3.2 1 1 2 3 3 3 2 Protein phosphatase 2C Snf7 PF03357.21 EGO58146.1 - 5.8e-35 120.4 19.7 5.8e-35 120.4 19.7 1.3 2 0 0 2 2 2 1 Snf7 RHH_8 PF17723.1 EGO58146.1 - 0.13 12.4 2.6 0.22 11.7 0.3 2.4 1 1 2 3 3 3 0 Ribbon-Helix-Helix transcriptional regulator family Ist1 PF03398.14 EGO58146.1 - 0.5 10.3 7.9 0.82 9.6 7.9 1.3 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway YlqD PF11068.8 EGO58146.1 - 2 8.8 18.8 3 8.2 5.4 2.1 1 1 1 2 2 2 0 YlqD protein Dynamin_N PF00350.23 EGO58147.1 - 6.5e-19 68.6 0.6 9.3e-18 64.8 0.0 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EGO58147.1 - 5.1e-10 39.4 0.0 3.6e-09 36.7 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO58147.1 - 4.7e-06 26.3 5.2 0.00016 21.2 5.6 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EGO58147.1 - 0.014 15.9 0.2 0.12 12.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain IIGP PF05049.13 EGO58147.1 - 0.026 13.6 0.0 0.065 12.3 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF1184 PF06683.11 EGO58147.1 - 0.027 13.9 0.2 0.062 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) RsgA_GTPase PF03193.16 EGO58147.1 - 0.03 14.2 1.7 2.8 7.8 0.1 2.8 3 0 0 3 3 2 0 RsgA GTPase cobW PF02492.19 EGO58147.1 - 0.04 13.5 0.2 1.1 8.8 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EGO58147.1 - 0.042 13.6 0.1 5.3 6.8 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EGO58147.1 - 0.053 13.9 0.1 0.84 10.0 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 EGO58147.1 - 0.056 13.7 0.1 3.4 7.9 0.0 2.6 1 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase BLOC1_2 PF10046.9 EGO58147.1 - 0.062 13.6 4.6 0.54 10.6 3.4 2.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TsaE PF02367.17 EGO58147.1 - 0.079 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MlaE PF02405.16 EGO58147.1 - 0.08 12.6 2.0 0.14 11.8 2.0 1.2 1 0 0 1 1 1 0 Permease MlaE FH2 PF02181.23 EGO58147.1 - 0.089 11.9 2.2 0.17 10.9 2.2 1.4 1 0 0 1 1 1 0 Formin Homology 2 Domain V_ATPase_I PF01496.19 EGO58147.1 - 1 7.2 3.0 1.6 6.5 3.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CN_hydrolase PF00795.22 EGO58148.1 - 7.6e-31 107.4 0.3 9.2e-31 107.1 0.3 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase A_deaminase PF00962.22 EGO58149.1 - 6.4e-27 94.7 0.0 8.6e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase WD40 PF00400.32 EGO58152.1 - 5e-37 125.3 20.3 3.1e-07 31.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO58152.1 - 6.4e-14 52.0 0.1 0.00037 20.7 0.1 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO58152.1 - 0.00016 20.7 0.1 1.5 7.7 0.0 3.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGO58152.1 - 0.0035 16.7 0.0 0.14 11.5 0.0 2.8 2 1 2 4 4 4 1 WD40-like domain Cytochrom_D1 PF02239.16 EGO58152.1 - 0.1 11.1 0.0 0.46 9.0 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain Phosducin PF02114.16 EGO58153.1 - 9.7e-10 37.8 0.0 2.2e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 Phosducin Ran_BP1 PF00638.18 EGO58155.1 - 3e-49 166.3 1.0 7e-49 165.1 1.0 1.6 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 EGO58155.1 - 0.0026 17.7 0.2 0.01 15.7 0.2 1.8 1 1 0 1 1 1 1 WH1 domain PS-DH PF14765.6 EGO58155.1 - 0.0075 15.5 1.5 0.0095 15.2 0.7 1.5 2 0 0 2 2 2 1 Polyketide synthase dehydratase VID27_PH PF17747.1 EGO58155.1 - 0.095 13.0 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 VID27 PH-like domain YEATS PF03366.16 EGO58156.1 - 1.4e-21 76.2 0.0 3.5e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 YEATS family BET PF17035.5 EGO58156.1 - 4.3e-05 23.6 0.4 9.7e-05 22.5 0.4 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Zn_clus PF00172.18 EGO58157.1 - 6.8e-07 29.3 12.1 1.1e-06 28.7 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 EGO58158.1 - 6.3e-42 143.7 0.0 9.5e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGO58158.1 - 6.6e-09 35.6 2.3 2.6e-08 33.6 0.4 2.4 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGO58158.1 - 0.0001 23.2 1.2 0.00034 21.5 0.0 2.3 2 1 1 3 3 3 1 AMP-binding enzyme C-terminal domain Imm71 PF15602.6 EGO58158.1 - 0.052 13.6 0.0 8.8 6.4 0.0 2.7 3 0 0 3 3 3 0 Immunity protein 71 Aminotran_1_2 PF00155.21 EGO58159.1 - 1.4e-62 211.9 0.0 2.2e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGO58159.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGO58159.1 - 0.032 13.5 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EGO58159.1 - 0.12 10.8 0.0 0.23 9.9 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme VATC PF18716.1 EGO58160.1 - 0.017 15.0 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 Vms1-associating treble clef domain DUF4211 PF13926.6 EGO58161.1 - 1.6e-19 70.4 1.7 2.4e-19 69.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) DREPP PF05558.12 EGO58161.1 - 0.0039 17.1 1.7 0.0039 17.1 1.7 3.6 3 1 0 3 3 3 1 DREPP plasma membrane polypeptide DUF3377 PF11857.8 EGO58161.1 - 0.69 9.9 2.3 1.2 9.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) GH131_N PF18271.1 EGO58162.1 - 2.1e-64 217.7 1.1 2.4e-64 217.5 1.1 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 EGO58162.1 - 0.57 10.0 7.9 1.8 8.4 7.9 1.8 1 1 0 1 1 1 0 Polysaccharide lyase MFS_2 PF13347.6 EGO58163.1 - 2.6e-10 39.4 3.4 2.6e-10 39.4 3.4 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.16 EGO58163.1 - 3.7e-07 29.4 29.9 1.6e-05 24.0 28.4 3.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Methyltransf_23 PF13489.6 EGO58164.1 - 4.1e-15 56.0 0.0 6.1e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO58164.1 - 9.2e-11 42.3 0.0 2.8e-10 40.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO58164.1 - 9.3e-10 39.0 0.0 1.9e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO58164.1 - 4.6e-08 33.7 0.0 2.1e-07 31.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO58164.1 - 1.3e-06 28.3 0.0 0.019 14.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 EGO58164.1 - 0.013 14.8 0.0 0.16 11.2 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGO58164.1 - 0.021 14.4 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 EGO58164.1 - 0.049 13.1 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 EGO58164.1 - 0.1 12.7 0.0 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 EGO58164.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Na_H_Exchanger PF00999.21 EGO58165.1 - 3.4e-72 243.3 36.1 4.4e-72 243.0 36.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM PF03929.16 EGO58165.1 - 0.022 14.4 0.1 0.053 13.2 0.1 1.7 1 0 0 1 1 1 0 PepSY-associated TM region DUF2461 PF09365.10 EGO58166.1 - 0.073 13.0 1.4 8.5 6.3 1.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) SOBP PF15279.6 EGO58166.1 - 0.16 12.5 8.4 0.35 11.5 8.4 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein DDRGK PF09756.9 EGO58166.1 - 1.9 8.0 16.6 3 7.4 16.6 1.2 1 0 0 1 1 1 0 DDRGK domain CENP-H PF05837.12 EGO58166.1 - 4.3 7.8 11.7 7.1 7.1 11.7 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SAM_1 PF00536.30 EGO58167.1 - 9.4e-17 61.2 0.0 1.8e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGO58167.1 - 2.3e-16 59.7 0.0 4.1e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EGO58167.1 - 2.6e-11 44.0 0.0 5e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 EGO58167.1 - 0.016 15.1 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) MAPEG PF01124.18 EGO58168.1 - 2e-14 53.6 2.0 2.4e-14 53.3 2.0 1.1 1 0 0 1 1 1 1 MAPEG family DUF2612 PF11041.8 EGO58168.1 - 0.032 14.2 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) RRM_1 PF00076.22 EGO58169.1 - 1.4e-11 44.0 0.1 2.5e-11 43.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4407 PF14362.6 EGO58169.1 - 5.9 6.1 8.3 8.3 5.7 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MerR-DNA-bind PF09278.11 EGO58170.1 - 0.27 11.8 0.9 0.48 11.0 0.9 1.3 1 0 0 1 1 1 0 MerR, DNA binding Fmp27 PF10344.9 EGO58171.1 - 2.5e-251 836.5 0.0 3.7e-251 836.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 EGO58171.1 - 5.5e-198 658.7 0.0 5.5e-198 658.7 0.0 2.8 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 EGO58171.1 - 2e-190 633.8 0.2 4.1e-190 632.7 0.2 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 EGO58171.1 - 8.2e-59 198.2 0.0 1.8e-58 197.0 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EGO58171.1 - 2.3e-54 183.5 0.2 5.4e-54 182.3 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EGO58171.1 - 2.5e-30 105.2 0.0 1.1e-29 103.1 0.0 2.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain ELFV_dehydrog PF00208.21 EGO58173.1 - 9.4e-68 228.5 0.0 1.5e-67 227.8 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EGO58173.1 - 4.1e-22 77.7 0.0 1e-16 59.8 0.0 2.6 2 1 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EGO58173.1 - 0.003 17.4 0.0 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Aminotran_5 PF00266.19 EGO58174.1 - 1.7e-15 56.9 0.1 1.8e-11 43.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGO58174.1 - 1.7e-05 23.6 0.0 2.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGO58174.1 - 0.00013 21.4 0.6 0.00022 20.6 0.6 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_L32e PF01655.18 EGO58175.1 - 8.4e-51 170.9 1.1 8.4e-51 170.9 1.1 1.4 1 1 1 2 2 2 1 Ribosomal protein L32 DnaJ_C PF01556.18 EGO58176.1 - 9.3e-36 123.1 0.0 1.4e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGO58176.1 - 1.4e-25 89.2 1.7 2.4e-25 88.4 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGO58176.1 - 1.6e-14 54.0 15.3 2.8e-14 53.2 15.3 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGO58176.1 - 0.0046 16.9 11.3 0.13 12.2 1.0 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein UreE_N PF02814.15 EGO58176.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain BMF PF15185.6 EGO58176.1 - 0.068 12.9 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis RseC_MucC PF04246.12 EGO58176.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC HypA PF01155.19 EGO58176.1 - 0.27 11.3 10.0 0.97 9.5 0.9 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA JAB PF01398.21 EGO58177.1 - 5.1e-31 107.1 0.2 9.5e-31 106.2 0.2 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EGO58177.1 - 3.8e-16 59.8 0.3 6.9e-16 58.9 0.3 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EGO58177.1 - 0.00013 21.7 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TraE PF05309.11 EGO58177.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 TraE protein PDH PF02153.17 EGO58178.1 - 1.1e-16 60.7 0.1 1.6e-16 60.1 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.19 EGO58178.1 - 0.037 13.4 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGO58178.1 - 0.087 13.4 0.3 0.47 11.1 0.1 2.2 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RCC1 PF00415.18 EGO58179.1 - 1.1e-35 122.0 14.4 4.2e-09 36.9 0.3 7.1 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGO58179.1 - 4.3e-17 61.4 30.4 3.5e-05 23.5 1.5 6.4 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.13 EGO58180.1 - 2.7e-50 171.2 0.0 3.2e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rep_fac-A_3 PF08661.11 EGO58180.1 - 0.056 13.8 0.1 0.11 12.8 0.1 1.5 1 1 0 1 1 1 0 Replication factor A protein 3 Rad1 PF02144.16 EGO58180.1 - 0.11 11.6 0.2 0.18 10.9 0.2 1.6 1 1 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 LRR_4 PF12799.7 EGO58181.1 - 0.2 12.1 4.1 1.1e+02 3.5 0.0 5.0 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) CDC37_N PF03234.14 EGO58182.1 - 1.5e-48 164.9 0.4 1.5e-48 164.9 0.4 3.3 4 0 0 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EGO58182.1 - 2.6e-40 137.0 1.0 2.6e-40 137.0 1.0 2.9 3 0 0 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EGO58182.1 - 9.6e-35 118.7 2.5 9.6e-35 118.7 2.5 2.8 2 0 0 2 2 2 1 Cdc37 C terminal domain Borrelia_REV PF03978.13 EGO58182.1 - 0.44 10.5 7.6 0.29 11.1 2.5 2.7 3 0 0 3 3 3 0 Borrelia burgdorferi REV protein RP-C_C PF11800.8 EGO58182.1 - 1.7 8.7 5.1 6.1 6.9 4.3 2.3 1 1 1 2 2 2 0 Replication protein C C-terminal region Spectrin PF00435.21 EGO58182.1 - 9.7 6.7 13.0 0.14 12.7 2.7 3.0 3 0 0 3 3 3 0 Spectrin repeat SDH_alpha PF03313.15 EGO58183.1 - 0.082 12.6 5.5 0.13 11.9 5.5 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain SPATA25 PF15218.6 EGO58184.1 - 0.071 12.9 0.0 0.086 12.6 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 25 SBDS_C PF09377.10 EGO58185.1 - 4.2e-45 152.5 0.1 6.6e-45 151.9 0.1 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EGO58185.1 - 1.9e-35 120.8 0.2 3.8e-35 119.8 0.2 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Enoyl_reductase PF12241.8 EGO58185.1 - 0.014 14.8 0.2 0.023 14.0 0.2 1.3 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Allexi_40kDa PF05549.11 EGO58185.1 - 0.015 14.8 1.3 0.71 9.3 0.0 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF627 PF04781.12 EGO58185.1 - 0.066 13.2 0.5 0.2 11.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Peptidase_S10 PF00450.22 EGO58186.1 - 4.1e-129 431.7 0.2 5e-129 431.4 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 EGO58186.1 - 1.6e-12 48.0 1.8 3.2e-12 47.1 1.8 1.5 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide PDEase_I PF00233.19 EGO58187.1 - 4.3e-56 190.3 0.0 6.8e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase UCH PF00443.29 EGO58188.1 - 5.9e-69 232.4 0.0 2e-68 230.7 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO58188.1 - 5.1e-14 52.6 0.0 4.4e-05 23.2 0.0 3.4 2 1 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGO58188.1 - 5.7e-12 46.1 0.0 1.4e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 DUSP domain Zn_ribbon_SprT PF17283.2 EGO58188.1 - 0.2 11.6 0.9 0.55 10.2 0.9 1.8 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Peptidase_M16_M PF16187.5 EGO58189.1 - 5.5e-96 321.1 0.1 1.1e-95 320.2 0.1 1.5 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 EGO58189.1 - 3.2e-41 141.4 0.0 1.7e-22 80.3 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGO58189.1 - 1.3e-35 122.6 2.8 5.1e-35 120.6 0.2 3.0 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) T4SS PF07996.11 EGO58189.1 - 0.091 13.2 0.2 0.21 12.0 0.2 1.6 1 0 0 1 1 1 0 Type IV secretion system proteins MPP6 PF10175.9 EGO58190.1 - 2.1e-07 31.5 6.6 1e-05 26.1 2.0 2.6 1 1 1 2 2 2 2 M-phase phosphoprotein 6 zf-CCHC PF00098.23 EGO58190.1 - 1e-05 25.4 4.9 1.6e-05 24.7 4.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGO58190.1 - 0.065 13.1 2.0 0.11 12.4 2.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CHCC PF10276.9 EGO58191.1 - 2e-16 59.8 0.9 3.2e-16 59.1 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger domain zf-C2H2_4 PF13894.6 EGO58191.1 - 0.068 14.0 1.5 0.91 10.5 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO58191.1 - 0.11 13.0 2.6 0.51 10.9 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type CdvA PF18822.1 EGO58193.1 - 0.012 15.4 1.3 0.028 14.3 0.2 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Methyltransf_31 PF13847.6 EGO58194.1 - 4.7e-14 52.5 0.0 7.6e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO58194.1 - 9.8e-09 35.8 0.0 3.2e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO58194.1 - 5.5e-08 33.5 0.0 1.3e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO58194.1 - 5.7e-07 30.1 0.0 6.6e-06 26.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO58194.1 - 6.3e-07 29.4 0.0 9.6e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO58194.1 - 1.6e-05 24.6 0.0 2.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EGO58194.1 - 0.00022 21.2 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EGO58194.1 - 0.0046 17.3 0.0 0.0087 16.4 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 EGO58194.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 EGO58194.1 - 0.21 10.9 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HEAT PF02985.22 EGO58195.1 - 4.8e-37 122.8 15.0 0.03 14.5 0.1 13.1 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 EGO58195.1 - 4.1e-33 113.6 6.6 1.2e-10 41.7 0.0 8.1 4 2 4 8 8 8 7 HEAT repeats HEAT_EZ PF13513.6 EGO58195.1 - 5.7e-12 45.9 7.0 0.029 14.9 0.1 8.1 8 2 2 10 10 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGO58195.1 - 4.2e-11 43.3 5.9 0.02 15.5 0.1 7.5 5 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGO58195.1 - 6.4e-10 39.3 12.5 0.0001 22.4 0.2 5.7 6 1 1 7 7 7 3 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EGO58195.1 - 1e-06 28.9 3.9 0.36 11.0 0.1 5.2 5 1 1 6 6 5 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 EGO58195.1 - 1.2e-05 24.1 12.5 0.00075 18.2 0.2 5.1 4 1 2 7 7 7 2 Adaptin N terminal region CLASP_N PF12348.8 EGO58195.1 - 0.0098 15.5 4.7 3.1 7.3 0.4 4.5 3 3 1 4 4 4 2 CLASP N terminal Arm PF00514.23 EGO58195.1 - 0.021 14.9 2.9 2.8 8.1 0.0 4.4 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat M11L PF11099.8 EGO58195.1 - 0.035 14.4 0.3 18 5.6 0.0 3.2 2 1 1 3 3 3 0 Apoptosis regulator M11L like Nop52 PF05997.12 EGO58195.1 - 0.063 13.1 0.0 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 Nucleolar protein,Nop52 Ecm29 PF13001.7 EGO58195.1 - 0.58 8.8 7.9 0.7 8.5 0.4 3.6 4 2 0 4 4 4 0 Proteasome stabiliser API5 PF05918.11 EGO58195.1 - 3.7 6.2 5.6 3.1 6.5 1.5 2.8 2 1 1 3 3 3 0 Apoptosis inhibitory protein 5 (API5) Myotub-related PF06602.14 EGO58196.1 - 1.7e-150 500.9 0.0 2.1e-150 500.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 EGO58196.1 - 0.022 14.6 0.0 0.068 13.0 0.0 1.8 1 0 0 1 1 1 0 GRAM domain Y_phosphatase3 PF13350.6 EGO58196.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Ribosomal_S3_C PF00189.20 EGO58197.1 - 1e-24 86.9 0.2 5.5e-24 84.5 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EGO58197.1 - 5.4e-12 45.4 0.1 1.1e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 EGO58197.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 EGO58197.1 - 0.11 12.3 0.3 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Coilin N-terminus Mg_trans_NIPA PF05653.14 EGO58198.1 - 4.9e-96 321.3 10.7 5.8e-96 321.1 10.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EGO58198.1 - 3.4e-05 24.0 4.6 3.4e-05 24.0 4.6 3.0 3 1 0 3 3 3 2 EamA-like transporter family DUF4293 PF14126.6 EGO58198.1 - 0.34 11.2 4.4 0.64 10.3 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF2420 PF10336.9 EGO58200.1 - 0.00013 22.0 0.7 0.00031 20.7 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.21 EGO58201.1 - 6.8e-19 68.3 0.0 9.9e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGO58201.1 - 1.6e-08 34.6 0.1 2.7e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 EGO58201.1 - 0.057 13.8 0.3 0.1 13.0 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) ANAPC4 PF12896.7 EGO58202.1 - 7.1e-42 143.2 0.3 1.6e-41 142.1 0.2 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EGO58202.1 - 7.8e-14 51.7 0.1 1.8e-13 50.6 0.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO58202.1 - 0.073 14.0 0.2 1.1 10.2 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat VASt PF16016.5 EGO58203.1 - 3e-36 125.1 0.2 5.6e-36 124.3 0.2 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 EGO58203.1 - 2.3e-13 50.4 0.0 5.2e-13 49.3 0.0 1.6 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 EGO58203.1 - 1.5e-05 25.5 0.1 4e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 EGO58203.1 - 0.02 14.8 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 GRAM domain Myosin_TH1 PF06017.13 EGO58203.1 - 0.045 13.4 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding RRM_1 PF00076.22 EGO58204.1 - 1.2e-08 34.6 0.0 0.00039 20.2 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 EGO58205.1 - 0.00039 20.7 0.1 1.7 9.0 0.0 4.1 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO58205.1 - 0.012 16.5 5.1 38 5.4 0.1 5.4 3 1 1 4 4 4 0 WD domain, G-beta repeat IKI3 PF04762.12 EGO58205.1 - 0.02 12.9 0.0 1 7.2 0.0 2.9 2 1 1 3 3 3 0 IKI3 family MoaC PF01967.21 EGO58206.1 - 5.3e-51 172.3 0.6 1.2e-50 171.2 0.6 1.6 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 EGO58206.1 - 1.6e-35 121.8 0.0 1.7e-34 118.5 0.0 2.2 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EGO58206.1 - 4.6e-25 88.9 0.0 9.5e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EGO58206.1 - 1.6e-05 25.2 0.0 8.6e-05 22.8 0.0 2.1 3 0 0 3 3 3 1 4Fe-4S single cluster domain IMUP PF15761.5 EGO58206.1 - 0.012 16.3 0.6 0.012 16.3 0.6 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein Fer4_14 PF13394.6 EGO58206.1 - 0.02 15.0 0.0 0.25 11.5 0.0 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain Synaptobrevin PF00957.21 EGO58207.1 - 1.7e-14 53.4 0.5 2.8e-14 52.7 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGO58207.1 - 2.8e-09 36.9 0.0 6.2e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.12 EGO58207.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region FYVE PF01363.21 EGO58208.1 - 8.9e-16 57.8 8.6 1.4e-15 57.2 8.6 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 EGO58208.1 - 0.76 10.0 13.2 0.14 12.3 8.0 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger ELO PF01151.18 EGO58210.1 - 1.8e-83 279.9 10.1 2.2e-83 279.6 10.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family WG_beta_rep PF14903.6 EGO58211.1 - 0.2 11.9 0.1 0.36 11.2 0.1 1.4 1 0 0 1 1 1 0 WG containing repeat GMC_oxred_N PF00732.19 EGO58212.1 - 5.9e-44 150.6 0.8 7.9e-44 150.2 0.8 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGO58212.1 - 6.8e-25 88.3 0.1 3.8e-24 85.9 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGO58212.1 - 2.8e-06 26.7 4.0 7.5e-06 25.3 4.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO58212.1 - 1.7e-05 24.2 1.3 8.7e-05 21.9 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGO58212.1 - 2.2e-05 23.9 0.0 6.1e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EGO58212.1 - 0.00027 21.1 1.1 0.00067 19.8 1.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGO58212.1 - 0.003 16.3 0.3 0.0046 15.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EGO58212.1 - 0.0086 15.7 1.6 0.22 11.1 0.7 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO58212.1 - 0.01 15.1 0.9 3.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO58212.1 - 0.033 13.4 0.2 0.082 12.1 0.2 1.6 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 EGO58212.1 - 0.098 12.2 2.9 0.17 11.5 2.9 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 EGO58212.1 - 0.14 11.2 0.4 1.5 7.8 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EGO58212.1 - 0.15 12.7 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO58212.1 - 0.16 11.3 0.9 0.22 10.9 0.9 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3074 PF11274.8 EGO58213.1 - 3.2e-53 180.5 1.0 2.5e-51 174.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3074) Pyr_redox_2 PF07992.14 EGO58216.1 - 5.2e-52 176.9 0.0 6.5e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO58216.1 - 6.8e-12 45.8 0.0 2.7e-10 40.7 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO58216.1 - 0.00032 20.1 0.0 0.2 10.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EcoR124_C PF12008.8 EGO58216.1 - 0.0019 17.9 0.1 0.0033 17.1 0.1 1.3 1 0 0 1 1 1 1 Type I restriction and modification enzyme - subunit R C terminal Tubulin_3 PF14881.6 EGO58217.1 - 2.1e-82 275.2 0.0 3.2e-82 274.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 EGO58217.1 - 3.5e-42 143.5 1.1 5.6e-42 142.8 0.1 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 EGO58217.1 - 0.00021 21.6 0.0 0.3 11.3 0.0 2.5 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain PAP_central PF04928.17 EGO58219.1 - 2.1e-109 364.3 0.0 2.8e-109 363.9 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EGO58219.1 - 1.9e-63 213.2 0.0 4.9e-63 211.8 0.0 1.8 2 1 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EGO58219.1 - 1.9e-08 34.4 0.0 5.7e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EGO58219.1 - 0.038 14.1 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Nrap_D2 PF17403.2 EGO58219.1 - 0.073 12.8 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Abhydrolase_6 PF12697.7 EGO58220.1 - 2.5e-06 28.3 2.3 4.4e-06 27.5 2.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EGO58220.1 - 0.00028 20.7 0.0 0.00054 19.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EGO58220.1 - 0.0036 16.9 0.0 0.0073 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EGO58220.1 - 0.0056 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EGO58220.1 - 0.0089 16.2 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 EGO58220.1 - 0.024 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 EGO58220.1 - 0.039 13.8 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGO58220.1 - 0.085 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PTPLA PF04387.14 EGO58221.1 - 1.5e-54 184.1 11.4 2.1e-54 183.6 11.4 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Methyltransf_23 PF13489.6 EGO58224.1 - 1.9e-13 50.6 0.0 3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO58224.1 - 2e-10 41.2 0.0 4.9e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO58224.1 - 7.4e-09 36.1 0.0 1.4e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO58224.1 - 6.6e-08 33.2 0.0 1.4e-07 32.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO58224.1 - 0.00013 21.8 0.0 0.0027 17.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO58224.1 - 0.00058 19.3 0.0 0.0033 16.8 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EGO58224.1 - 0.086 12.3 0.0 0.086 12.3 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Herpes_BLLF1 PF05109.13 EGO58224.1 - 5.7 4.8 8.9 7.3 4.4 8.9 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Arf PF00025.21 EGO58225.1 - 4.1e-75 251.1 0.1 4.7e-75 250.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGO58225.1 - 6.5e-15 55.4 0.0 9.1e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGO58225.1 - 1.7e-13 50.4 0.0 2.2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGO58225.1 - 1.2e-11 44.5 0.0 1.4e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EGO58225.1 - 1.4e-11 44.2 0.3 2.3e-07 30.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGO58225.1 - 8.5e-09 35.1 0.0 1.1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGO58225.1 - 5.9e-07 29.6 0.0 9.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO58225.1 - 8.4e-05 22.2 0.1 0.0064 16.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGO58225.1 - 0.0084 15.6 0.8 0.032 13.8 0.8 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 EGO58225.1 - 0.11 13.0 0.1 0.18 12.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain Ribosomal_L39 PF00832.20 EGO58226.1 - 5.6e-22 77.1 9.2 6.4e-22 76.9 9.2 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Skp1 PF01466.19 EGO58227.1 - 1.7e-29 101.7 0.4 3.5e-29 100.7 0.4 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EGO58227.1 - 7.2e-23 80.5 0.2 1.8e-22 79.2 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF615 PF04751.14 EGO58227.1 - 0.061 13.3 1.8 2.9 7.9 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF615) Glyco_transf_22 PF03901.17 EGO58228.1 - 2.5e-49 168.6 13.4 1.9e-26 93.3 1.6 2.1 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family Pet100 PF09803.9 EGO58229.1 - 2.8e-21 75.8 0.5 3.4e-21 75.5 0.5 1.2 1 0 0 1 1 1 1 Pet100 ATPase_gene1 PF09527.10 EGO58229.1 - 0.033 14.3 0.2 0.043 14.0 0.2 1.1 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Nitr_red_bet_C PF14711.6 EGO58229.1 - 0.04 13.6 0.8 0.055 13.2 0.8 1.1 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal DUF2576 PF10845.8 EGO58229.1 - 0.11 12.2 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Transcrip_reg PF01709.20 EGO58230.1 - 8.6e-70 234.9 2.0 9.9e-70 234.7 2.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator DUF2067 PF09840.9 EGO58230.1 - 0.1 12.2 0.7 0.31 10.6 0.4 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) Vac14_Fab1_bd PF12755.7 EGO58231.1 - 2.8e-10 40.7 0.4 0.0026 18.3 0.0 5.5 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EGO58231.1 - 2.5e-09 37.4 3.9 0.027 14.8 0.0 8.3 7 1 1 8 8 8 2 HEAT repeats CLASP_N PF12348.8 EGO58231.1 - 2.4e-05 24.0 1.1 0.092 12.3 0.1 4.8 5 0 0 5 5 5 1 CLASP N terminal HEAT PF02985.22 EGO58231.1 - 2.7e-05 24.0 29.3 0.057 13.7 0.0 11.0 13 0 0 13 13 12 2 HEAT repeat Adaptin_N PF01602.20 EGO58231.1 - 0.0019 16.9 2.7 1.4 7.4 0.2 5.5 3 1 0 4 4 4 1 Adaptin N terminal region UNC45-central PF11701.8 EGO58231.1 - 0.0068 16.4 4.0 0.43 10.5 0.0 4.3 5 0 0 5 5 5 1 Myosin-binding striated muscle assembly central V-ATPase_H_C PF11698.8 EGO58231.1 - 0.055 13.6 0.0 81 3.4 0.0 4.1 3 0 0 3 3 3 0 V-ATPase subunit H DUF374 PF04028.13 EGO58231.1 - 0.082 12.5 1.6 0.71 9.5 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF374) Arm PF00514.23 EGO58231.1 - 0.48 10.6 4.5 40 4.4 0.0 5.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TetR_C_15 PF17918.1 EGO58231.1 - 0.55 11.0 3.7 2.7 8.8 0.0 4.1 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain HEAT_EZ PF13513.6 EGO58231.1 - 2.7 8.6 16.5 3.8 8.1 0.0 7.2 9 0 0 9 9 9 0 HEAT-like repeat DUF1640 PF07798.11 EGO58232.1 - 5.2e-46 156.9 3.8 6.8e-46 156.5 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) SOG2 PF10428.9 EGO58232.1 - 0.097 11.9 10.4 0.14 11.3 10.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Abhydrolase_6 PF12697.7 EGO58233.1 - 1.1e-11 45.8 0.5 1.9e-11 45.0 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO58233.1 - 1.7e-11 43.9 0.0 4.3e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DSPc PF00782.20 EGO58233.1 - 8.3e-08 32.1 0.0 2e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.20 EGO58233.1 - 3.7e-07 30.0 0.0 0.00077 19.2 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 EGO58233.1 - 0.00052 19.7 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase PTPlike_phytase PF14566.6 EGO58233.1 - 0.00065 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Lipase_3 PF01764.25 EGO58233.1 - 0.0021 17.9 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) BAAT_C PF08840.11 EGO58233.1 - 0.0041 17.1 0.0 2.9 7.8 0.0 2.9 2 1 1 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 EGO58233.1 - 0.0047 16.7 0.0 0.0089 15.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Y_phosphatase PF00102.27 EGO58233.1 - 0.0088 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FSH1 PF03959.13 EGO58233.1 - 0.015 15.0 0.0 0.15 11.7 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) LIDHydrolase PF10230.9 EGO58233.1 - 0.021 14.4 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 EGO58233.1 - 0.034 14.0 0.1 0.13 12.1 0.0 2.0 3 0 0 3 3 2 0 Serine hydrolase LCAT PF02450.15 EGO58233.1 - 0.094 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 EGO58233.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_4 PF08386.10 EGO58233.1 - 0.12 12.5 0.1 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 TAP-like protein VirJ PF06057.11 EGO58233.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF900 PF05990.12 EGO58233.1 - 0.2 11.1 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) SnoaL_2 PF12680.7 EGO58234.1 - 0.0066 17.1 0.0 0.0086 16.7 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain Alk_phosphatase PF00245.20 EGO58235.1 - 2.2e-104 349.7 0.0 2.6e-104 349.5 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EGO58235.1 - 4.1e-06 26.3 0.1 8.2e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EGO58235.1 - 0.0066 15.9 0.1 0.76 9.1 0.0 2.2 2 0 0 2 2 2 2 Sulfatase RskA PF10099.9 EGO58235.1 - 0.036 14.4 0.3 0.086 13.1 0.3 1.6 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3357 PF11837.8 EGO58235.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF3328 PF11807.8 EGO58235.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) HLH PF00010.26 EGO58236.1 - 1.6e-12 47.2 0.4 3.5e-12 46.1 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DivIC PF04977.15 EGO58236.1 - 0.018 14.8 4.9 0.037 13.8 4.7 1.6 1 1 0 1 1 1 0 Septum formation initiator Pox_A30L_A26L PF06086.12 EGO58236.1 - 0.03 14.0 0.1 0.047 13.4 0.1 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein Alpha_GJ PF03229.13 EGO58236.1 - 0.66 10.5 5.7 1.3 9.6 5.7 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J CLTH PF10607.9 EGO58237.1 - 1.5e-34 119.0 0.0 3.1e-34 118.0 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EGO58237.1 - 0.0046 16.9 0.1 0.012 15.6 0.1 1.7 1 0 0 1 1 1 1 LisH CAF1 PF04857.20 EGO58238.1 - 4.2e-22 78.7 3.9 2.7e-10 39.9 0.0 3.1 3 0 0 3 3 3 2 CAF1 family ribonuclease DDHD PF02862.17 EGO58238.1 - 0.0058 16.8 1.0 0.03 14.5 0.1 2.1 2 0 0 2 2 2 1 DDHD domain TFIIA PF03153.13 EGO58238.1 - 0.16 11.9 27.0 0.045 13.8 16.3 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 EGO58238.1 - 0.16 12.3 7.5 0.28 11.5 3.9 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Neur_chan_memb PF02932.16 EGO58238.1 - 0.46 10.5 5.1 0.41 10.7 3.2 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.8 EGO58238.1 - 1.2 8.7 24.2 0.043 13.4 15.5 2.2 2 0 0 2 2 2 0 Spt20 family CCDC53 PF10152.9 EGO58238.1 - 1.8 9.0 12.1 0.3 11.5 2.7 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex eIF-3_zeta PF05091.12 EGO58238.1 - 1.8 7.5 8.7 3.3 6.6 8.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 EGO58238.1 - 2.6 6.2 15.5 4.2 5.5 15.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.7 EGO58238.1 - 5.4 5.0 6.4 8.6 4.3 6.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NDUF_B12 PF08122.12 EGO58239.1 - 1e-23 83.1 0.1 1.4e-23 82.7 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Golgin_A5 PF09787.9 EGO58240.1 - 0.0024 17.4 2.7 0.004 16.7 2.7 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 APG6_N PF17675.1 EGO58240.1 - 0.027 15.0 2.9 0.049 14.2 2.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 EGO58240.1 - 0.049 14.1 4.0 4.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Cell division protein ZapB ADIP PF11559.8 EGO58240.1 - 0.13 12.3 2.3 0.29 11.2 2.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2570 PF10828.8 EGO58240.1 - 0.14 11.9 0.7 0.27 11.1 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) SlyX PF04102.12 EGO58240.1 - 0.18 12.5 3.0 3.5 8.3 1.9 2.8 2 0 0 2 2 2 0 SlyX Med9 PF07544.13 EGO58240.1 - 2.1 8.5 5.6 20 5.4 0.9 2.9 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ATG16 PF08614.11 EGO58240.1 - 3.9 7.6 10.8 0.049 13.9 1.8 2.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) eIF-6 PF01912.18 EGO58241.1 - 1.7e-81 272.3 0.5 2.2e-81 272.0 0.5 1.1 1 0 0 1 1 1 1 eIF-6 family ThiF PF00899.21 EGO58243.1 - 8.6e-28 97.3 0.0 1.2e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family TFIIA PF03153.13 EGO58243.1 - 0.023 14.7 10.7 0.03 14.3 10.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EGO58243.1 - 2.6 7.6 21.1 4.7 6.7 21.1 1.3 1 0 0 1 1 1 0 Spt20 family DUF2431 PF10354.9 EGO58245.1 - 3.6e-64 216.1 0.0 4.3e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) DUF3238 PF11579.8 EGO58245.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3238) DUF2841 PF11001.8 EGO58246.1 - 3.2e-40 137.0 1.8 6.1e-40 136.1 1.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) FERM_F2 PF18377.1 EGO58247.1 - 0.0014 18.6 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 FERM F2 acyl-CoA binding protein-like domain ABC_membrane PF00664.23 EGO58248.1 - 2.2e-86 289.9 22.1 5.9e-46 157.3 5.2 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGO58248.1 - 4e-52 176.4 0.0 9.7e-30 103.9 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGO58248.1 - 8e-11 41.8 0.0 0.00011 21.7 0.0 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGO58248.1 - 8.7e-06 25.8 1.0 0.16 12.1 0.3 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO58248.1 - 0.00029 20.8 0.1 0.22 11.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGO58248.1 - 0.00031 21.2 1.1 0.011 16.2 0.6 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EGO58248.1 - 0.0017 18.1 0.3 1.3 8.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EGO58248.1 - 0.0029 17.7 0.6 0.35 10.9 0.1 2.6 2 0 0 2 2 2 1 Dynamin family AAA_15 PF13175.6 EGO58248.1 - 0.0041 16.9 0.9 0.27 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EGO58248.1 - 0.0048 17.4 1.1 0.51 10.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 EGO58248.1 - 0.0059 16.7 0.8 0.35 10.9 0.3 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_29 PF13555.6 EGO58248.1 - 0.009 15.7 1.8 4.6 7.0 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGO58248.1 - 0.014 15.3 0.8 5.3 6.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 EGO58248.1 - 0.084 13.3 0.0 11 6.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 EGO58248.1 - 0.092 12.1 0.0 12 5.1 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 EGO58248.1 - 0.095 12.6 2.4 0.86 9.5 0.0 3.0 3 0 0 3 3 3 0 NACHT domain T2SSE PF00437.20 EGO58248.1 - 0.11 11.5 0.4 0.49 9.4 0.1 2.0 1 1 1 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 EGO58248.1 - 0.14 12.5 1.4 24 5.2 0.3 3.2 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 EGO58248.1 - 0.26 11.5 0.9 38 4.5 0.1 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MWFE PF15879.5 EGO58248.1 - 0.76 10.0 4.8 0.4 10.9 0.4 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit 60KD_IMP PF02096.20 EGO58248.1 - 1.9 8.4 9.3 0.47 10.3 5.0 2.2 2 0 0 2 2 2 0 60Kd inner membrane protein UPF0047 PF01894.17 EGO58249.1 - 2.2e-37 127.8 0.0 2.5e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 NUDIX_2 PF13869.6 EGO58250.1 - 4.5e-81 270.9 0.0 5.3e-81 270.7 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase SUKH-3 PF14433.6 EGO58250.1 - 0.18 12.3 0.0 2.1 8.8 0.0 2.5 2 1 0 2 2 2 0 SUKH-3 immunity protein Dynamin_N PF00350.23 EGO58251.1 - 5.3e-18 65.6 0.1 5e-17 62.5 0.0 2.7 3 1 0 3 3 2 1 Dynamin family MMR_HSR1 PF01926.23 EGO58251.1 - 1.7e-06 28.1 0.1 2.2e-05 24.5 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EGO58251.1 - 3.3e-05 24.4 3.4 0.00012 22.6 0.0 3.3 3 1 0 4 4 4 1 ABC transporter RsgA_GTPase PF03193.16 EGO58251.1 - 0.0016 18.4 0.0 0.0063 16.4 0.0 2.0 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 EGO58251.1 - 0.0064 15.8 0.2 0.15 11.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AIG1 PF04548.16 EGO58251.1 - 0.013 14.9 0.1 0.12 11.6 0.1 2.5 2 0 0 2 2 2 0 AIG1 family AAA_22 PF13401.6 EGO58251.1 - 0.023 15.0 0.0 0.23 11.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGO58251.1 - 0.035 13.6 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IIGP PF05049.13 EGO58251.1 - 0.038 13.1 0.8 0.089 11.8 0.1 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) SMC_N PF02463.19 EGO58251.1 - 0.073 12.5 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGO58251.1 - 0.1 13.0 0.1 1.2 9.5 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain Prominin PF05478.11 EGO58251.1 - 0.46 8.4 8.7 0.085 10.8 0.7 2.6 3 0 0 3 3 3 0 Prominin AAA_23 PF13476.6 EGO58251.1 - 0.94 9.9 10.5 3.7 8.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 EGO58251.1 - 1.7 8.7 4.4 4.5 7.3 0.2 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain KfrA_N PF11740.8 EGO58251.1 - 1.9 9.2 10.8 3.6 8.3 0.1 4.5 4 0 0 4 4 4 0 Plasmid replication region DNA-binding N-term CCDC74_C PF14917.6 EGO58251.1 - 1.9 9.0 6.1 3.1 8.4 0.2 3.7 3 1 0 3 3 3 0 Coiled coil protein 74, C terminal Phasin PF05597.11 EGO58251.1 - 8.1 6.5 8.4 1.3 9.0 0.4 3.5 4 0 0 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Gluconate_2-dh3 PF13618.6 EGO58251.1 - 9.9 6.4 7.4 6.8 6.9 0.2 3.6 4 0 0 4 4 4 0 Gluconate 2-dehydrogenase subunit 3 Peptidase_M28 PF04389.17 EGO58253.1 - 8.7e-33 113.7 0.0 1.3e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Pkinase PF00069.25 EGO58254.1 - 2.7e-77 259.7 0.0 3.3e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO58254.1 - 5.6e-38 130.7 0.2 8.9e-38 130.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO58254.1 - 0.00082 18.4 0.0 0.011 14.7 0.0 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGO58254.1 - 0.011 15.1 0.1 0.021 14.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGO58254.1 - 0.054 12.8 0.1 0.18 11.1 0.0 1.8 1 1 0 2 2 2 0 Kinase-like SCA7 PF08313.12 EGO58256.1 - 4.2e-31 106.6 0.1 1.1e-30 105.4 0.1 1.7 1 0 0 1 1 1 1 SCA7, zinc-binding domain SURF2 PF05477.11 EGO58256.1 - 1.2 8.8 12.9 4.1 7.0 12.9 1.9 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 EGO58256.1 - 2 6.6 9.1 3.2 5.9 9.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Mito_carr PF00153.27 EGO58257.1 - 2.8e-46 155.4 2.1 2.6e-14 52.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.7 EGO58257.1 - 0.041 14.4 0.0 0.9 10.1 0.0 2.4 2 0 0 2 2 2 0 YtxH-like protein DUF4692 PF15763.5 EGO58257.1 - 0.057 13.9 2.4 0.11 13.0 2.4 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DUF3446 PF11928.8 EGO58257.1 - 0.12 12.7 16.6 0.24 11.7 16.6 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain SR-25 PF10500.9 EGO58257.1 - 0.38 10.3 22.4 0.75 9.4 22.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 EGO58257.1 - 1.9 9.4 9.0 4.8 8.1 9.0 1.7 1 0 0 1 1 1 0 Chorion family 2 zf-RING_UBOX PF13445.6 EGO58258.1 - 1.1e-07 31.8 14.6 7.6e-05 22.7 3.9 2.9 3 0 0 3 3 3 2 RING-type zinc-finger zf-NOSIP PF15906.5 EGO58258.1 - 2.1e-06 27.8 0.0 5.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 EGO58258.1 - 1.3e-05 25.4 17.9 0.0002 21.6 5.2 3.2 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 EGO58258.1 - 1.3e-05 24.9 17.4 7e-05 22.6 2.9 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO58258.1 - 4.1e-05 23.5 5.7 4.1e-05 23.5 5.7 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO58258.1 - 8.4e-05 22.4 21.9 0.00077 19.3 3.0 3.4 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 EGO58258.1 - 8.5e-05 22.6 12.1 0.00022 21.3 5.6 2.9 2 2 0 2 2 2 1 FYVE zinc finger zf-C3HC4_3 PF13920.6 EGO58258.1 - 9.1e-05 22.2 17.3 0.0016 18.3 7.5 3.2 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 EGO58258.1 - 0.0025 17.7 1.8 0.0071 16.2 1.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 EGO58258.1 - 0.0025 17.2 10.3 0.0025 17.2 10.3 3.2 2 2 0 2 2 1 1 Rtf2 RING-finger Rad50_zn_hook PF04423.14 EGO58258.1 - 0.042 13.7 6.9 0.5 10.2 1.1 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.6 EGO58258.1 - 0.2 11.8 14.6 1.1 9.5 5.8 3.4 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING DZR PF12773.7 EGO58258.1 - 0.35 10.9 16.4 1.3 9.1 3.9 3.5 2 1 1 3 3 3 0 Double zinc ribbon Prok-RING_4 PF14447.6 EGO58258.1 - 1.1 9.1 22.2 0.21 11.5 7.5 3.8 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 HA2 PF04408.23 EGO58258.1 - 4.4 7.6 11.2 0.27 11.5 1.4 3.0 2 1 1 3 3 3 0 Helicase associated domain (HA2) Acyltransferase PF01553.21 EGO58259.1 - 4.8e-15 55.4 0.0 1.4e-14 53.9 0.0 1.7 1 1 0 1 1 1 1 Acyltransferase NTF2 PF02136.20 EGO58261.1 - 8.4e-26 90.9 0.2 1.4e-25 90.2 0.2 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EGO58261.1 - 0.0094 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EGO58261.1 - 7.7 7.1 17.6 26 5.4 17.6 2.0 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 PH_9 PF15410.6 EGO58262.1 - 3.7e-12 46.7 0.0 5.8e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EGO58262.1 - 0.0047 17.4 0.1 0.01 16.3 0.1 1.6 1 0 0 1 1 1 1 PH domain TMEM252 PF15664.5 EGO58262.1 - 0.058 13.1 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 252 family Keratin_B2 PF01500.17 EGO58263.1 - 0.0055 16.7 5.3 0.006 16.6 5.3 1.1 1 0 0 1 1 1 1 Keratin, high sulfur B2 protein Nnf1 PF03980.14 EGO58264.1 - 1.9e-32 111.9 3.0 2e-32 111.8 0.1 2.8 2 0 0 2 2 2 1 Nnf1 DivIC PF04977.15 EGO58264.1 - 0.27 11.0 1.3 0.78 9.6 1.3 1.7 1 0 0 1 1 1 0 Septum formation initiator Cytochrom_B561 PF03188.16 EGO58264.1 - 3.2 7.9 14.3 0.075 13.2 7.6 1.7 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 DUF3918 PF13056.6 EGO58264.1 - 4.2 7.1 5.1 1.4 8.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3918) PAT1 PF09770.9 EGO58264.1 - 7.5 4.7 23.8 19 3.4 23.8 1.6 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PIR PF00399.19 EGO58266.1 - 2.5e-17 61.9 50.3 0.00015 21.2 2.7 6.6 6 0 0 6 6 6 6 Yeast PIR protein repeat HMG_box PF00505.19 EGO58267.1 - 3.2e-08 33.9 4.0 1.4e-05 25.4 1.8 2.8 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EGO58267.1 - 0.003 18.1 2.8 0.003 18.1 2.8 2.9 3 0 0 3 3 3 1 HMG-box domain Cpn60_TCP1 PF00118.24 EGO58268.1 - 5.3e-151 503.6 12.4 6e-151 503.4 12.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2204 PF09970.9 EGO58268.1 - 0.027 14.1 0.1 8.2 6.0 0.0 2.7 2 0 0 2 2 2 0 Nucleotidyl transferase of unknown function (DUF2204) PH_10 PF15411.6 EGO58270.1 - 4.4e-29 101.2 0.1 7.5e-29 100.5 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 EGO58270.1 - 4.2e-14 53.2 0.0 6.3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EGO58270.1 - 7.4e-10 39.0 0.1 2.4e-09 37.3 0.1 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 EGO58270.1 - 0.0016 18.7 6.3 0.0028 17.9 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGO58270.1 - 0.028 14.4 6.7 0.047 13.7 6.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.11 EGO58270.1 - 0.044 14.1 4.5 0.075 13.4 4.5 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.6 EGO58270.1 - 0.077 12.8 5.6 0.14 12.0 5.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGO58270.1 - 0.08 12.6 6.0 0.025 14.2 3.0 1.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DUF1147 PF06615.11 EGO58270.1 - 0.14 12.3 0.3 0.35 10.9 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-C3HC4_3 PF13920.6 EGO58270.1 - 0.23 11.3 2.7 0.45 10.4 2.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO58270.1 - 0.25 11.2 6.1 0.46 10.4 6.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGO58270.1 - 0.65 9.8 4.6 1.5 8.7 4.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-C3H2C3 PF17122.5 EGO58270.1 - 4 7.5 9.0 1.2 9.2 5.0 2.2 2 0 0 2 2 2 0 Zinc-finger zf-rbx1 PF12678.7 EGO58270.1 - 5.4 7.4 11.5 0.059 13.7 3.5 1.9 2 0 0 2 2 1 0 RING-H2 zinc finger domain DUF1272 PF06906.11 EGO58270.1 - 6.5 6.9 6.6 20 5.4 6.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) MFS_1 PF07690.16 EGO58271.1 - 7e-22 77.8 38.0 8.1e-21 74.3 37.9 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO58271.1 - 3.1e-06 25.9 17.2 9.1e-06 24.4 17.2 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sacchrp_dh_NADP PF03435.18 EGO58272.1 - 1e-13 51.7 0.0 2e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ribosomal_L37ae PF01780.19 EGO58274.1 - 3.2e-39 132.9 7.6 3.6e-39 132.7 7.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 EGO58274.1 - 0.00027 21.0 1.1 0.00038 20.5 1.1 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_ribbon_SprT PF17283.2 EGO58274.1 - 0.0027 17.6 2.7 0.0049 16.8 2.7 1.4 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 EGO58274.1 - 0.0038 17.2 3.4 0.0066 16.4 3.4 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Ephrin_rec_like PF07699.13 EGO58274.1 - 0.0083 15.9 0.6 0.012 15.3 0.6 1.3 1 0 0 1 1 1 1 Putative ephrin-receptor like zf-BED PF02892.15 EGO58274.1 - 0.013 15.6 5.3 0.27 11.3 0.7 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 EGO58274.1 - 0.018 15.5 1.3 0.63 10.6 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Elf1 PF05129.13 EGO58274.1 - 0.031 14.3 2.1 0.053 13.6 2.1 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DUF1451 PF07295.11 EGO58274.1 - 0.048 13.7 0.4 0.066 13.2 0.4 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain C1_2 PF03107.16 EGO58274.1 - 0.079 13.3 2.3 1.4 9.3 2.5 2.0 1 1 1 2 2 2 0 C1 domain CarbpepA_inh PF02977.15 EGO58274.1 - 0.12 12.1 0.7 0.12 12.1 0.7 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor PHD PF00628.29 EGO58275.1 - 1.2e-09 37.9 6.0 1.2e-09 37.9 6.0 2.7 2 1 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.7 EGO58275.1 - 2e-07 31.2 9.5 3.8e-06 27.1 2.3 3.0 3 0 0 3 3 3 2 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGO58275.1 - 5.6e-06 26.6 3.5 5.6e-06 26.6 3.5 4.1 3 1 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 EGO58275.1 - 0.00046 20.0 3.9 0.00046 20.0 3.9 3.3 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGO58275.1 - 0.00088 19.1 1.6 0.00088 19.1 1.6 3.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 EGO58275.1 - 0.0026 17.3 2.8 0.0026 17.3 2.8 2.4 2 0 0 2 2 2 1 PHD-finger zf-C3HC4 PF00097.25 EGO58275.1 - 0.004 17.0 3.6 0.004 17.0 3.6 3.7 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO58275.1 - 0.0084 16.1 2.5 0.0084 16.1 2.5 3.4 4 0 0 4 4 3 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGO58275.1 - 0.012 15.7 2.8 0.012 15.7 2.8 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-PHD-like PF15446.6 EGO58275.1 - 0.013 15.1 1.8 0.013 15.1 1.8 2.7 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-C3HC4_3 PF13920.6 EGO58275.1 - 0.014 15.2 2.0 0.014 15.2 2.0 4.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) CDC24_OB3 PF17244.2 EGO58275.1 - 0.055 13.2 0.7 0.098 12.3 0.7 1.3 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 DZR PF12773.7 EGO58275.1 - 1.5 8.9 5.5 60 3.8 5.5 2.8 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.6 EGO58275.1 - 5 7.1 16.0 0.1 12.5 2.1 3.2 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 Prim_Zn_Ribbon PF08273.12 EGO58275.1 - 6.2 7.2 6.4 41 4.6 0.3 3.2 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase MRP-L46 PF11788.8 EGO58276.1 - 1.2e-39 135.7 0.2 2.1e-39 134.9 0.2 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 EGO58276.1 - 7.7e-05 22.8 0.4 0.00025 21.1 0.1 2.0 2 0 0 2 2 2 1 NUDIX domain CAF1 PF04857.20 EGO58277.1 - 1.3e-44 152.7 0.0 1.7e-44 152.3 0.0 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease DUF155 PF02582.14 EGO58278.1 - 1.1e-52 178.6 0.5 1.7e-52 178.1 0.5 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF3535 PF12054.8 EGO58280.1 - 4.4e-127 424.9 0.0 4.7e-126 421.6 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EGO58280.1 - 3.6e-66 223.3 0.0 9.1e-66 221.9 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO58280.1 - 2.5e-17 63.2 0.0 6.3e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 EGO58280.1 - 7.3e-16 56.9 2.1 0.0057 16.8 0.0 8.2 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.6 EGO58280.1 - 3.4e-09 37.0 2.3 0.00034 20.9 0.1 6.1 5 0 0 5 5 5 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EGO58280.1 - 1.9e-06 28.4 1.3 1.6 9.4 0.0 4.0 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGO58280.1 - 0.05 14.1 15.2 11 6.6 0.0 8.2 10 0 0 10 10 10 0 HEAT-like repeat SMC_N PF02463.19 EGO58282.1 - 5.1e-61 205.9 15.3 9.1e-61 205.1 15.3 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGO58282.1 - 2.1e-19 70.0 0.0 1.2e-18 67.5 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EGO58282.1 - 7.6e-15 55.5 12.6 8.3e-08 32.4 0.1 3.8 2 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGO58282.1 - 5.3e-13 49.9 33.6 5.3e-13 49.9 33.6 7.5 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 EGO58282.1 - 1.7e-09 37.9 69.6 2.2e-07 30.9 25.4 4.3 2 2 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 EGO58282.1 - 0.00094 19.4 0.2 0.0035 17.5 0.2 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGO58282.1 - 0.0027 17.4 0.0 0.0072 16.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain BRE1 PF08647.11 EGO58282.1 - 0.0077 16.3 9.0 0.0077 16.3 9.0 8.2 3 3 4 8 8 8 2 BRE1 E3 ubiquitin ligase ABC_tran PF00005.27 EGO58282.1 - 0.36 11.4 0.0 0.36 11.4 0.0 6.0 3 2 1 4 4 4 0 ABC transporter FPRL1_inhibitor PF16104.5 EGO58282.1 - 6 7.1 8.8 1.2 9.3 0.1 3.8 3 0 0 3 3 3 0 Formyl peptide receptor-like 1 inhibitory protein Velvet PF11754.8 EGO58284.1 - 1.6e-52 179.0 0.1 1.1e-35 123.9 0.0 3.6 2 2 1 3 3 3 2 Velvet factor U3_snoRNA_assoc PF08297.11 EGO58286.1 - 1.8e-11 44.5 2.8 1.8e-11 44.5 2.8 4.9 3 2 0 3 3 3 1 U3 snoRNA associated DUF4051 PF13260.6 EGO58286.1 - 0.42 10.4 1.2 15 5.4 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) DUF1501 PF07394.12 EGO58286.1 - 5 6.1 8.9 9.1 5.2 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) TFIIA PF03153.13 EGO58286.1 - 7.6 6.4 30.5 10 6.0 30.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TIM PF00121.18 EGO58287.1 - 6.4e-91 304.0 0.2 7.3e-91 303.9 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 EGO58287.1 - 0.11 11.9 0.0 0.37 10.2 0.0 1.7 1 1 1 2 2 2 0 CutC family L51_S25_CI-B8 PF05047.16 EGO58288.1 - 1.3e-16 60.2 0.0 2.5e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain GHL10 PF02638.15 EGO58288.1 - 0.21 10.6 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 U1snRNP70_N PF12220.8 EGO58289.1 - 3.9e-26 91.5 3.9 1e-25 90.1 3.9 1.8 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EGO58289.1 - 2.3e-16 59.4 0.1 8.1e-16 57.6 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO58289.1 - 5.1e-05 23.3 0.0 8.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif Ribosomal_L10 PF00466.20 EGO58290.1 - 2.7e-24 85.2 0.0 4e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 EGO58290.1 - 7.2e-23 80.4 0.0 1.1e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P ABC_membrane PF00664.23 EGO58291.1 - 2.7e-105 351.9 36.9 2.5e-56 191.4 14.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGO58291.1 - 3.9e-67 225.0 0.0 1.9e-32 112.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGO58291.1 - 1.2e-12 47.8 0.0 0.00031 20.3 0.0 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGO58291.1 - 4e-07 29.7 1.5 0.0056 16.4 0.2 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGO58291.1 - 5.6e-07 29.6 0.1 0.1 12.5 0.0 3.6 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EGO58291.1 - 9.9e-07 29.3 5.4 0.0085 16.5 0.0 3.7 2 2 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 EGO58291.1 - 9.1e-06 24.7 4.7 0.017 13.9 0.1 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 EGO58291.1 - 5.7e-05 22.8 0.1 0.089 12.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EGO58291.1 - 0.00011 22.0 0.0 0.49 10.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 EGO58291.1 - 0.00023 21.6 3.3 3 8.3 0.1 4.7 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO58291.1 - 0.00032 21.0 0.9 0.61 10.4 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EGO58291.1 - 0.00069 19.4 1.3 2.1 8.0 0.1 3.6 2 1 0 2 2 2 2 AAA domain G-alpha PF00503.20 EGO58291.1 - 0.0019 17.4 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_21 PF13304.6 EGO58291.1 - 0.002 18.0 1.5 3.1 7.5 0.0 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGO58291.1 - 0.0051 17.0 2.1 4.4 7.6 0.2 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 EGO58291.1 - 0.0094 15.5 0.0 4.6 6.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 EGO58291.1 - 0.018 15.2 0.0 10 6.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGO58291.1 - 0.018 15.6 0.1 13 6.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EGO58291.1 - 0.018 15.0 0.2 13 5.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EGO58291.1 - 0.025 13.9 0.0 4.6 6.5 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 EGO58291.1 - 0.029 14.9 0.9 3.9 7.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 EGO58291.1 - 0.032 14.3 3.1 8.6 6.4 0.2 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain SRP54 PF00448.22 EGO58291.1 - 0.042 13.5 0.1 4.6 6.8 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF815 PF05673.13 EGO58291.1 - 0.05 12.8 0.0 9.6 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EGO58291.1 - 0.11 12.9 0.0 20 5.6 0.0 3.4 3 0 0 3 3 2 0 RNA helicase MMR_HSR1 PF01926.23 EGO58291.1 - 0.11 12.5 0.3 20 5.3 0.0 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EGO58291.1 - 0.12 12.0 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EGO58291.1 - 0.14 12.1 0.1 0.63 9.9 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 EGO58291.1 - 0.85 9.8 8.1 0.64 10.3 0.1 3.0 3 0 0 3 3 2 0 AAA domain SARAF PF06682.12 EGO58292.1 - 9.1e-106 354.2 8.2 1.1e-105 354.0 8.2 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis BRE1 PF08647.11 EGO58293.1 - 9.6e-29 99.3 4.5 9.6e-29 99.3 4.5 6.3 3 2 3 6 6 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 EGO58293.1 - 2.6e-09 36.8 7.1 4.1e-09 36.2 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO58293.1 - 1.8e-08 34.1 6.9 3e-08 33.4 6.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGO58293.1 - 5e-08 32.7 7.1 8.7e-08 31.9 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO58293.1 - 1.3e-07 31.5 9.3 2.4e-07 30.6 9.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGO58293.1 - 1.7e-07 31.1 4.5 3.6e-07 30.1 4.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGO58293.1 - 1.7e-07 31.0 8.7 3.2e-07 30.1 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO58293.1 - 1.3e-06 28.7 7.8 2.4e-06 27.8 7.8 1.4 1 0 0 1 1 1 1 Ring finger domain Snapin_Pallidin PF14712.6 EGO58293.1 - 0.0016 18.8 5.9 0.0016 18.8 5.9 6.5 4 3 0 5 5 5 1 Snapin/Pallidin FAM184 PF15665.5 EGO58293.1 - 0.0035 17.1 24.9 0.0035 17.1 24.9 5.9 1 1 4 5 5 5 2 Family with sequence similarity 184, A and B zf-C3HC4_4 PF15227.6 EGO58293.1 - 0.01 16.0 6.6 0.022 14.9 6.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ZapB PF06005.12 EGO58293.1 - 0.016 15.7 7.1 0.016 15.7 7.1 9.0 2 1 3 5 5 4 0 Cell division protein ZapB zf-RING_6 PF14835.6 EGO58293.1 - 0.024 14.5 4.4 0.057 13.3 4.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1192 PF06698.11 EGO58293.1 - 0.029 14.4 0.8 0.029 14.4 0.8 7.5 7 1 3 10 10 7 0 Protein of unknown function (DUF1192) zf-RING_4 PF14570.6 EGO58293.1 - 0.03 14.1 3.9 0.035 13.9 2.2 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EGO58293.1 - 0.064 13.6 7.2 0.35 11.2 6.5 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-H2C2_2 PF13465.6 EGO58293.1 - 0.098 13.1 1.2 3.5 8.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain EFG_II PF14492.6 EGO58293.1 - 0.12 12.5 1.3 7.7 6.7 0.2 3.3 2 0 0 2 2 2 0 Elongation Factor G, domain II zf-C2H2_4 PF13894.6 EGO58293.1 - 0.74 10.8 3.5 5.2 8.2 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger GIT_CC PF16559.5 EGO58293.1 - 1.4 8.9 29.3 0.088 12.7 0.6 6.1 7 0 0 7 7 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor Baculo_PEP_C PF04513.12 EGO58293.1 - 2.3 8.3 34.6 1.4 8.9 0.6 4.9 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus FYVE PF01363.21 EGO58293.1 - 4.8 7.4 11.0 52 4.1 11.0 2.4 1 1 0 1 1 1 0 FYVE zinc finger PKcGMP_CC PF16808.5 EGO58293.1 - 6 6.8 18.4 0.14 12.0 3.6 4.4 4 0 0 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-C2H2_jaz PF12171.8 EGO58293.1 - 6.3 7.2 5.4 8.6 6.8 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ATG16 PF08614.11 EGO58293.1 - 8.7 6.5 85.7 0.2 11.9 18.7 5.6 2 1 2 5 5 5 0 Autophagy protein 16 (ATG16) DUF1829 PF08862.10 EGO58293.1 - 9.3 6.8 12.6 1.9 9.0 2.4 3.8 4 0 0 4 4 3 0 Domain of unknown function DUF1829 Myb_DNA-bind_7 PF15963.5 EGO58294.1 - 2.7e-27 94.5 2.5 1e-26 92.7 2.5 2.1 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EGO58294.1 - 8.4e-08 32.3 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO58294.1 - 0.00085 19.5 0.1 0.0022 18.2 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain XPC-binding PF09280.11 EGO58295.1 - 9.7e-25 86.1 13.2 1.7e-24 85.3 13.2 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 EGO58295.1 - 1e-22 79.6 0.6 1.8e-22 78.9 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EGO58295.1 - 1e-21 76.5 5.8 1.1e-11 44.4 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.8 EGO58295.1 - 7.6e-10 38.5 0.5 1.6e-09 37.4 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EGO58295.1 - 0.0065 16.6 0.1 0.021 15.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGO58295.1 - 0.01 16.4 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGO58295.1 - 0.015 15.6 1.8 0.022 15.1 0.5 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain WIYLD PF10440.9 EGO58295.1 - 0.026 14.3 0.6 2.4 8.0 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain UBA_3 PF09288.10 EGO58295.1 - 0.039 13.8 0.0 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Ubiquitin_2 PF14560.6 EGO58295.1 - 0.047 14.1 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain DUF1421 PF07223.11 EGO58295.1 - 0.098 12.5 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 UBA-like domain (DUF1421) Pneumo_att_G PF05539.11 EGO58295.1 - 0.29 10.7 4.9 0.41 10.2 4.9 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Herpes_DNAp_acc PF04929.12 EGO58295.1 - 1.9 7.4 8.1 3.4 6.5 8.1 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TFIIA PF03153.13 EGO58295.1 - 5.8 6.8 10.6 9.5 6.1 10.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUR7 PF06687.12 EGO58296.1 - 5.1 6.7 9.7 2.1 8.0 7.1 1.6 1 1 0 1 1 1 0 SUR7/PalI family DIOX_N PF14226.6 EGO58298.1 - 4.4e-06 27.4 0.0 1.7e-05 25.6 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGO58298.1 - 5.1e-05 23.7 0.0 8.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Phage_holin_1 PF04531.13 EGO58299.1 - 0.059 13.9 0.2 0.059 13.9 0.2 2.4 3 0 0 3 3 3 0 Bacteriophage holin Peptidase_M14 PF00246.24 EGO58301.1 - 2.3e-86 290.2 0.1 2.8e-86 289.9 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EGO58301.1 - 2.9e-06 27.6 0.0 7.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Zn_clus PF00172.18 EGO58302.1 - 7.1e-08 32.4 13.2 1.3e-07 31.6 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RdRP PF05183.12 EGO58303.1 - 1.4e-133 446.6 0.0 1.8e-133 446.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF3602 PF12223.8 EGO58304.1 - 0.013 16.1 2.4 0.015 15.9 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3602) Asp PF00026.23 EGO58306.1 - 6.5e-35 121.1 4.8 2.1e-21 76.7 0.3 3.1 3 0 0 3 3 3 3 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGO58306.1 - 0.00083 19.2 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 EGO58306.1 - 0.051 13.8 1.4 0.24 11.6 0.0 2.5 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal E1-E2_ATPase PF00122.20 EGO58308.1 - 6.5e-43 146.4 4.1 6.5e-43 146.4 4.1 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGO58308.1 - 1.7e-21 77.5 0.0 3.9e-21 76.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGO58308.1 - 0.0036 17.7 0.0 0.0083 16.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGO58308.1 - 0.0044 16.8 0.1 0.44 10.2 0.0 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EGO58308.1 - 0.13 11.8 0.6 11 5.4 0.1 2.6 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase Ribosomal_S5_C PF03719.15 EGO58308.1 - 0.42 10.1 3.3 0.24 10.9 0.4 2.1 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain Nramp PF01566.18 EGO58309.1 - 3e-90 302.8 21.5 1.5e-89 300.5 21.5 1.9 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Med22 PF06179.12 EGO58310.1 - 2.7e-12 46.8 0.0 3.8e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PseudoU_synth_1 PF01416.20 EGO58311.1 - 3.9e-12 46.6 0.0 2.3e-10 40.9 0.0 2.7 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 EGO58311.1 - 0.033 14.0 0.1 0.57 10.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) MgtE_N PF03448.17 EGO58311.1 - 0.076 13.6 0.2 0.18 12.4 0.2 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain HET PF06985.11 EGO58312.1 - 8.8e-38 129.9 4.2 1.7e-37 129.0 4.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ParE-like_toxin PF15781.5 EGO58312.1 - 0.082 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 ParE-like toxin of type II bacterial toxin-antitoxin system ATP_transf PF09830.9 EGO58316.1 - 2.5e-23 82.0 0.1 6.4e-23 80.7 0.1 1.7 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.23 EGO58316.1 - 0.016 15.9 0.1 0.029 15.1 0.1 1.4 1 0 0 1 1 1 0 HIT domain DUF5081 PF16887.5 EGO58316.1 - 0.025 13.7 1.1 0.047 12.8 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5081) Scs3p PF10261.9 EGO58317.1 - 5.6e-78 261.9 3.2 7.2e-78 261.5 3.2 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Pectate_lyase_3 PF12708.7 EGO58318.1 - 1e-103 345.8 10.6 9.7e-89 296.8 3.8 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EGO58318.1 - 3.4e-07 29.9 1.9 0.0044 16.7 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase WD40 PF00400.32 EGO58319.1 - 9.5e-30 102.2 15.2 7.3e-06 26.6 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 EGO58319.1 - 1.1e-10 41.2 0.1 2.1e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO58319.1 - 7.8e-09 35.2 0.1 1.5e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EGO58319.1 - 3.5e-06 27.2 0.1 0.052 13.9 0.0 4.3 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO58319.1 - 1.4e-05 24.0 0.6 1.1 7.8 0.0 3.7 3 2 1 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EGO58319.1 - 0.013 15.1 0.4 0.1 12.1 0.4 2.3 1 1 0 1 1 1 0 PQQ-like domain Cytochrom_D1 PF02239.16 EGO58319.1 - 0.026 13.1 0.0 0.049 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF5046 PF16465.5 EGO58319.1 - 0.046 13.2 0.1 10 5.4 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5046) F-box_4 PF15966.5 EGO58319.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 F-box Ge1_WD40 PF16529.5 EGO58319.1 - 0.18 10.8 0.1 2.4 7.0 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DbpA PF03880.15 EGO58320.1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 DbpA RNA binding domain Glyco_hydro_61 PF03443.14 EGO58321.1 - 1.4e-58 198.2 0.0 1.9e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SLAC1 PF03595.17 EGO58323.1 - 5.7e-86 288.7 39.2 6.5e-86 288.5 39.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel RINGv PF12906.7 EGO58324.1 - 4.8e-16 58.6 10.4 8.1e-16 57.9 10.4 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EGO58324.1 - 0.0037 17.6 9.6 0.0068 16.7 9.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EGO58324.1 - 0.55 10.3 3.1 1.3 9.1 3.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2870 PF11069.8 EGO58325.1 - 0.0083 16.5 2.0 0.38 11.2 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) Apolipoprotein PF01442.18 EGO58325.1 - 0.093 12.6 53.1 3.9 7.3 2.5 6.4 4 1 2 6 6 6 0 Apolipoprotein A1/A4/E domain acVLRF1 PF18859.1 EGO58325.1 - 1.2 9.4 19.1 0.11 12.8 7.0 4.0 3 0 0 3 3 3 0 Actinobacteria/chloroflexi VLRF1 release factor DUF2408 PF10303.9 EGO58325.1 - 2.5 8.7 9.0 14 6.2 6.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) HeLo PF14479.6 EGO58326.1 - 3.4e-09 36.9 0.3 0.00069 19.5 0.1 2.7 1 1 1 2 2 2 2 Prion-inhibition and propagation PIP5K PF01504.18 EGO58327.1 - 6.1e-46 156.8 0.0 9.4e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cofilin_ADF PF00241.20 EGO58327.1 - 3.3e-33 114.1 0.0 1.1e-17 63.9 0.0 2.4 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein HET PF06985.11 EGO58328.1 - 1.4e-26 93.6 0.0 2.3e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_10 PF00331.20 EGO58330.1 - 1.2e-89 300.6 0.0 1.4e-89 300.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DsrD PF08679.11 EGO58330.1 - 0.19 12.0 0.1 0.46 10.8 0.1 1.6 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) LANC_like PF05147.13 EGO58331.1 - 4.5e-24 84.7 0.0 1.1e-22 80.1 0.0 2.0 2 0 0 2 2 2 2 Lanthionine synthetase C-like protein Hydrophobin_2 PF06766.11 EGO58333.1 - 3.4e-28 97.4 9.5 4.7e-28 96.9 9.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Ferric_reduct PF01794.19 EGO58335.1 - 5.2e-16 58.9 12.8 5.2e-16 58.9 12.8 2.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGO58335.1 - 1.9e-15 56.9 0.0 3.9e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EGO58335.1 - 6.8e-13 49.0 0.0 1.2e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain tRNA-synt_1d PF00750.19 EGO58336.1 - 3.4e-99 332.1 1.4 4.4e-99 331.7 1.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EGO58336.1 - 5.6e-30 104.0 0.1 1.4e-29 102.6 0.1 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EGO58336.1 - 1e-05 26.0 0.0 2.7e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain p450 PF00067.22 EGO58338.1 - 9.4e-52 176.3 0.0 2.2e-51 175.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 KIF1B PF12423.8 EGO58338.1 - 0.43 11.1 5.4 1.4 9.4 5.4 1.9 1 0 0 1 1 1 0 Kinesin protein 1B FAD_binding_4 PF01565.23 EGO58339.1 - 2.4e-28 98.6 1.8 3.6e-28 98.0 1.8 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGO58339.1 - 2.3e-14 53.2 0.1 4.6e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like RE_TdeIII PF09520.10 EGO58340.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII An_peroxidase PF03098.15 EGO58341.1 - 3.6e-117 392.1 0.0 4.2e-117 391.9 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase FancD2 PF14631.6 EGO58345.1 - 0.16 9.4 0.7 0.19 9.1 0.7 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Pox_Ag35 PF03286.14 EGO58345.1 - 0.27 11.0 7.6 0.37 10.6 7.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PTPRCAP PF15713.5 EGO58345.1 - 6.1 7.1 15.3 9.2 6.5 15.3 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF2277 PF10041.9 EGO58346.1 - 0.16 12.3 3.1 4.4 7.7 0.0 2.2 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) MerR-DNA-bind PF09278.11 EGO58346.1 - 1.7 9.3 4.1 0.71 10.5 0.2 2.0 2 0 0 2 2 2 0 MerR, DNA binding Hamartin PF04388.12 EGO58350.1 - 3.6 6.1 13.2 3.6 6.1 12.5 1.3 1 1 0 1 1 1 0 Hamartin protein PALP PF00291.25 EGO58352.1 - 8.5e-66 222.3 0.0 1.1e-65 222.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EGO58352.1 - 5.6e-15 55.5 0.0 1.1e-09 38.6 0.0 3.0 2 0 0 2 2 2 2 CBS domain SRPRB PF09439.10 EGO58353.1 - 2e-22 79.5 0.0 4.9e-20 71.7 0.0 3.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EGO58353.1 - 3.3e-05 24.3 1.1 5.9e-05 23.5 0.3 1.9 2 1 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.27 EGO58353.1 - 0.00027 20.6 0.0 0.0056 16.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGO58353.1 - 0.0089 16.1 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO58353.1 - 0.014 15.3 0.5 0.24 11.3 0.4 2.6 3 0 0 3 3 3 0 RsgA GTPase TniB PF05621.11 EGO58353.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Zeta_toxin PF06414.12 EGO58353.1 - 0.022 14.0 0.2 0.039 13.2 0.2 1.3 1 0 0 1 1 1 0 Zeta toxin Arf PF00025.21 EGO58353.1 - 0.035 13.6 0.0 0.79 9.2 0.0 2.4 2 1 0 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.6 EGO58353.1 - 0.041 14.2 0.0 0.089 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGO58353.1 - 0.095 12.3 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 EGO58353.1 - 0.11 13.1 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EGO58353.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DHHC PF01529.20 EGO58354.1 - 8e-36 123.1 12.8 8e-36 123.1 12.8 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 EGO58354.1 - 5.6e-27 94.1 0.0 1e-12 48.4 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGO58354.1 - 5.5e-23 80.3 0.1 7e-05 23.1 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EGO58354.1 - 8.6e-23 80.4 0.6 4.3e-07 30.4 0.2 4.6 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO58354.1 - 2.4e-22 78.7 0.1 2.8e-07 30.7 0.0 5.2 3 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO58354.1 - 4e-22 75.9 0.7 8.3e-07 28.8 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat PocR PF10114.9 EGO58354.1 - 0.89 9.3 3.3 2 8.2 3.3 1.5 1 0 0 1 1 1 0 Sensory domain found in PocR DUF5518 PF17647.1 EGO58354.1 - 8.7 6.5 12.5 1.5 9.0 0.3 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5518) DLH PF01738.18 EGO58356.1 - 2.6e-22 79.5 0.0 3.3e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EGO58356.1 - 0.017 14.7 0.0 0.035 13.8 0.0 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Tropomyosin_1 PF12718.7 EGO58357.1 - 0.014 15.5 1.1 0.029 14.5 1.1 1.4 1 0 0 1 1 1 0 Tropomyosin like Syntaxin-6_N PF09177.11 EGO58357.1 - 0.019 15.5 0.7 0.071 13.7 0.4 2.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal SIKE PF05769.11 EGO58357.1 - 0.034 14.1 1.4 0.062 13.2 1.4 1.3 1 0 0 1 1 1 0 SIKE family Methyltransf_23 PF13489.6 EGO58357.1 - 0.055 13.3 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Occludin_ELL PF07303.13 EGO58357.1 - 0.057 14.1 3.3 0.15 12.8 3.3 1.6 1 0 0 1 1 1 0 Occludin homology domain Fis1_TPR_N PF14852.6 EGO58357.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat CotJB PF12652.7 EGO58357.1 - 0.088 13.0 2.0 0.23 11.7 2.0 1.7 1 0 0 1 1 1 0 CotJB protein CcmH PF03918.14 EGO58357.1 - 0.15 11.3 0.1 0.33 10.3 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DHR10 PF18595.1 EGO58357.1 - 0.57 10.3 5.0 0.09 12.8 0.4 2.1 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain zf-CCCH_2 PF14608.6 EGO58357.1 - 4 8.0 12.3 3.7 8.2 3.4 3.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Gp5_C PF06715.12 EGO58358.1 - 0.75 10.1 3.4 29 5.1 0.3 2.8 2 0 0 2 2 2 0 Gp5 C-terminal repeat (3 copies) NicO PF03824.16 EGO58360.1 - 1.2e-66 224.9 6.0 1.6e-66 224.5 6.0 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein Syndecan PF01034.20 EGO58360.1 - 0.23 11.4 0.1 0.23 11.4 0.1 2.7 3 0 0 3 3 3 0 Syndecan domain Glycos_transf_2 PF00535.26 EGO58361.1 - 1.7e-25 89.8 0.1 2.6e-25 89.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 EGO58361.1 - 1.3e-20 74.2 1.0 1.3e-20 74.2 1.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EGO58361.1 - 2e-20 73.0 0.0 3.2e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EGO58361.1 - 1.1e-14 54.9 0.1 1.5e-14 54.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cellulose_synt PF03552.14 EGO58361.1 - 2.5e-05 23.0 3.5 0.00098 17.7 0.5 2.4 2 1 0 2 2 2 2 Cellulose synthase Glyco_hydro_12 PF01670.16 EGO58362.1 - 9.6e-15 55.1 5.2 3.6e-13 50.0 5.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 UDPG_MGDP_dh_N PF03721.14 EGO58363.1 - 6.1e-51 172.7 0.1 5.7e-35 120.6 0.0 2.5 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EGO58363.1 - 6.9e-28 96.7 0.0 1.8e-27 95.4 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EGO58363.1 - 7.1e-25 87.5 0.0 2.4e-19 69.7 0.0 3.3 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 EGO58363.1 - 0.0017 18.6 0.1 0.049 13.8 0.1 2.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 EGO58363.1 - 0.16 12.3 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Binary_toxB PF03495.14 EGO58364.1 - 0.32 11.2 2.2 0.39 11.0 0.4 2.1 2 0 0 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain DUF3439 PF11921.8 EGO58366.1 - 0.022 14.7 9.4 0.053 13.5 9.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 EGO58366.1 - 1.8 6.5 6.3 2.6 5.9 6.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Acyl_transf_3 PF01757.22 EGO58367.1 - 1.1e-31 110.2 36.7 1.5e-31 109.8 36.7 1.2 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.15 EGO58368.1 - 0.0044 17.6 0.1 0.017 15.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif MEKHLA PF08670.11 EGO58368.1 - 0.1 12.5 1.8 0.22 11.4 1.3 1.8 2 0 0 2 2 2 0 MEKHLA domain Bud13 PF09736.9 EGO58368.1 - 1.4 9.4 11.0 2.1 8.7 11.0 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex FSH1 PF03959.13 EGO58369.1 - 1.5e-24 86.8 0.0 1.9e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EGO58369.1 - 8.6e-06 26.5 0.6 0.00014 22.5 0.4 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family PADR1 PF08063.12 EGO58370.1 - 0.41 10.5 2.3 0.81 9.5 0.2 2.2 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-PHD-like PF15446.6 EGO58372.1 - 2.8 7.5 8.4 1.4 8.5 2.5 2.1 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain DUF4058 PF13267.6 EGO58373.1 - 0.039 13.4 0.1 0.051 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) DUF3331 PF11811.8 EGO58373.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) Peptidase_C50 PF03568.17 EGO58376.1 - 0.26 10.4 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C50 LacI PF00356.21 EGO58379.1 - 0.095 12.5 0.5 0.22 11.4 0.5 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family SVS_QK PF10578.9 EGO58380.1 - 0.063 13.8 0.2 8.7 7.2 0.0 2.9 1 1 0 2 2 2 0 Seminal vesicle protein repeat PHA_synth_III_E PF09712.10 EGO58397.1 - 0.0012 18.1 0.1 0.0041 16.3 0.0 1.7 1 1 1 2 2 2 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Filament PF00038.21 EGO58397.1 - 0.019 14.5 0.9 0.029 14.0 0.9 1.2 1 0 0 1 1 1 0 Intermediate filament protein FlxA PF14282.6 EGO58397.1 - 0.024 14.6 0.1 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 FlxA-like protein Lectin_N PF03954.14 EGO58397.1 - 0.54 10.0 2.3 1.2 8.9 2.3 1.6 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain C1_1 PF00130.22 EGO58400.1 - 0.046 13.6 2.1 0.075 12.9 2.1 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.19 EGO58400.1 - 0.67 10.0 2.1 1.1 9.3 2.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NUDIX PF00293.28 EGO58401.1 - 3.8e-12 46.4 0.2 8.2e-12 45.3 0.1 1.6 2 0 0 2 2 2 1 NUDIX domain NUDE_C PF04880.13 EGO58403.1 - 1.9e-40 139.2 13.1 1.9e-40 139.2 13.1 4.6 3 3 3 6 6 3 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 EGO58403.1 - 0.0035 17.8 9.2 0.0035 17.8 9.2 5.0 2 1 2 4 4 3 1 Cell division protein ZapB Tropomyosin_1 PF12718.7 EGO58403.1 - 0.068 13.3 39.4 0.86 9.7 25.5 3.4 2 1 1 3 3 3 0 Tropomyosin like CENP-F_leu_zip PF10473.9 EGO58403.1 - 0.082 12.9 38.4 0.13 12.3 16.5 3.8 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 EGO58403.1 - 0.11 10.0 23.8 0.18 9.3 23.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sec16 PF12932.7 EGO58403.1 - 0.15 12.6 2.2 0.43 11.2 0.8 2.6 1 1 1 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region Fez1 PF06818.15 EGO58403.1 - 1.5 9.2 30.5 2.5 8.5 15.1 3.1 2 1 1 3 3 3 0 Fez1 Filament PF00038.21 EGO58403.1 - 2.3 7.7 34.4 6.2 6.3 32.1 2.4 2 1 0 2 2 2 0 Intermediate filament protein AAA_13 PF13166.6 EGO58403.1 - 2.7 6.5 22.8 4.4 5.8 22.8 1.3 1 0 0 1 1 1 0 AAA domain Chibby PF14645.6 EGO58403.1 - 2.9 8.3 18.2 2.6 8.5 4.7 3.7 3 1 1 4 4 4 0 Chibby family IFT57 PF10498.9 EGO58403.1 - 3.2 6.6 22.7 0.075 12.0 10.9 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 NACHT PF05729.12 EGO58404.1 - 3.4e-06 27.1 0.0 9.3e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 EGO58404.1 - 0.038 13.2 0.0 0.29 10.3 0.0 2.1 1 1 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 EGO58404.1 - 0.1 12.9 0.0 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mis12 PF05859.12 EGO58404.1 - 0.17 11.9 1.3 0.55 10.3 1.3 1.8 1 0 0 1 1 1 0 Mis12 protein Dicty_REP PF05086.12 EGO58404.1 - 0.98 7.3 6.8 1.8 6.4 6.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.32 EGO58405.1 - 9.1e-42 140.3 24.2 5.8e-07 30.1 0.0 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.8 EGO58405.1 - 1.5e-11 43.6 2.6 0.0029 16.3 0.0 4.2 3 1 1 4 4 4 4 Nucleoporin Nup120/160 F-box-like PF12937.7 EGO58405.1 - 1.3e-09 37.8 0.3 4.1e-09 36.2 0.3 1.9 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EGO58405.1 - 7.1e-09 35.8 0.5 0.25 11.6 0.0 5.8 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 EGO58405.1 - 2.8e-08 33.4 0.1 2.1e-07 30.6 0.0 2.3 1 1 1 2 2 2 1 F-box domain F-box_4 PF15966.5 EGO58405.1 - 0.00046 20.1 0.8 0.0017 18.2 0.0 2.3 2 0 0 2 2 2 1 F-box WD40_like PF17005.5 EGO58405.1 - 0.0066 15.8 1.0 2.4 7.4 0.1 2.5 1 1 0 2 2 2 2 WD40-like domain Frtz PF11768.8 EGO58405.1 - 0.063 11.6 0.0 0.094 11.0 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Mito_carr PF00153.27 EGO58407.1 - 1.5e-67 223.5 5.0 1.4e-21 76.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4702 PF15774.5 EGO58408.1 - 0.11 11.5 0.5 0.14 11.1 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) Acyl_transf_3 PF01757.22 EGO58410.1 - 8.8e-21 74.3 18.1 1.8e-20 73.3 18.0 1.8 1 1 0 1 1 1 1 Acyltransferase family DUF3159 PF11361.8 EGO58410.1 - 0.24 11.1 4.6 0.15 11.8 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3159) F-box-like PF12937.7 EGO58411.1 - 1.6e-05 24.7 1.4 5.3e-05 23.0 1.4 2.0 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 EGO58411.1 - 0.03 14.3 0.2 0.46 10.5 0.1 2.4 2 0 0 2 2 2 0 F-box-like domain SOG2 PF10428.9 EGO58412.1 - 0.68 9.1 8.8 0.41 9.8 3.6 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Erythro-docking PF09277.11 EGO58412.1 - 0.73 9.8 2.9 0.83 9.6 0.1 2.5 2 0 0 2 2 2 0 Erythronolide synthase, docking EOS1 PF12326.8 EGO58413.1 - 2.8 7.8 5.5 30 4.5 4.9 2.5 2 0 0 2 2 2 0 N-glycosylation protein HAUS-augmin3 PF14932.6 EGO58415.1 - 4.2e-05 23.2 2.6 4.2e-05 23.2 2.6 1.8 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 DAHP_synth_2 PF01474.16 EGO58415.1 - 0.042 12.4 0.0 0.21 10.0 0.0 2.0 2 0 0 2 2 2 0 Class-II DAHP synthetase family DUF3450 PF11932.8 EGO58415.1 - 4 6.7 11.7 8.2 5.6 10.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 EGO58415.1 - 8.1 7.0 7.0 6.2 7.4 1.7 2.6 1 1 2 3 3 3 0 Protein of unknown function DUF16 LrgB PF04172.16 EGO58416.1 - 2e-19 70.0 17.3 3.2e-11 43.2 3.7 2.8 3 0 0 3 3 3 2 LrgB-like family DUF3054 PF11255.8 EGO58416.1 - 0.032 14.7 0.6 0.032 14.7 0.6 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3054) Rotamase PF00639.21 EGO58417.1 - 5.4e-23 81.8 0.0 9.4e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EGO58417.1 - 5.4e-17 62.4 0.0 7.3e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EGO58417.1 - 4.4e-09 36.3 1.6 4.4e-09 36.3 1.6 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 EGO58417.1 - 3.1e-05 24.8 0.0 4.7e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain SUIM_assoc PF16619.5 EGO58417.1 - 0.0061 16.6 2.6 0.015 15.3 2.6 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF3636 PF12331.8 EGO58417.1 - 0.074 12.9 0.2 0.098 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) RNA_POL_M_15KD PF02150.16 EGO58418.1 - 7e-10 38.6 3.6 7e-10 38.6 3.6 2.2 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit DUF1462 PF07315.11 EGO58418.1 - 0.02 15.1 0.1 0.042 14.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) Nudix_N_2 PF14803.6 EGO58418.1 - 0.051 13.5 0.9 0.051 13.5 0.9 2.2 2 0 0 2 2 2 0 Nudix N-terminal Ribosomal_L14 PF00238.19 EGO58419.1 - 8e-47 158.3 5.5 9.4e-47 158.1 5.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SET PF00856.28 EGO58420.1 - 1.2e-09 38.8 0.4 9.7e-09 35.8 0.1 2.5 2 1 0 2 2 2 1 SET domain Tmemb_55A PF09788.9 EGO58420.1 - 0.0007 18.8 0.2 0.0026 16.9 0.2 2.0 1 0 0 1 1 1 1 Transmembrane protein 55A FAM76 PF16046.5 EGO58420.1 - 0.0025 17.2 0.8 0.0025 17.2 0.8 3.2 4 0 0 4 4 4 1 FAM76 protein DUF4224 PF13986.6 EGO58420.1 - 0.1 12.5 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) BTB PF00651.31 EGO58421.1 - 0.004 17.4 0.0 0.011 16.0 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain Epimerase PF01370.21 EGO58422.1 - 5.7e-20 71.8 0.1 9.8e-19 67.8 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGO58422.1 - 1.8e-12 47.5 0.1 2.6e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGO58422.1 - 1.1e-10 41.0 0.0 1.6e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGO58422.1 - 2.8e-06 26.7 0.1 4.3e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGO58422.1 - 4.8e-06 26.2 0.5 4.1e-05 23.1 0.0 2.5 1 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGO58422.1 - 2.3e-05 23.7 0.4 8.1e-05 21.9 0.4 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EGO58422.1 - 0.00019 21.1 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 EGO58422.1 - 0.0055 16.8 0.0 0.013 15.6 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 EGO58422.1 - 0.0083 16.4 0.1 0.069 13.4 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EGO58422.1 - 0.012 16.1 0.1 0.028 14.8 0.1 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DFP PF04127.15 EGO58422.1 - 0.013 15.3 0.1 0.022 14.6 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein adh_short PF00106.25 EGO58422.1 - 0.032 13.7 0.1 0.09 12.2 0.1 1.8 1 1 0 1 1 1 0 short chain dehydrogenase Ldh_1_N PF00056.23 EGO58422.1 - 0.16 12.1 0.1 0.31 11.1 0.1 1.5 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Topo-VIb_trans PF09239.11 EGO58424.1 - 0.061 13.1 0.1 0.16 11.8 0.1 1.6 2 0 0 2 2 2 0 Topoisomerase VI B subunit, transducer CCDC73 PF15818.5 EGO58425.1 - 0.046 11.6 1.1 0.06 11.2 1.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family Pox_A_type_inc PF04508.12 EGO58426.1 - 0.022 14.6 0.2 0.052 13.4 0.2 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF2937 PF11157.8 EGO58426.1 - 0.035 13.8 1.1 0.08 12.6 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF3439 PF11921.8 EGO58432.1 - 0.27 11.2 5.9 0.93 9.5 5.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) NACHT PF05729.12 EGO58435.1 - 6.9e-12 45.6 0.6 6.9e-12 45.6 0.6 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EGO58435.1 - 1e-06 29.2 0.8 3.5e-06 27.5 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGO58435.1 - 0.00014 22.2 0.0 0.00058 20.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EGO58435.1 - 0.00018 20.9 1.0 0.028 13.7 0.3 2.6 1 1 1 2 2 2 1 KAP family P-loop domain ABC_tran PF00005.27 EGO58435.1 - 0.0022 18.5 0.2 0.025 15.1 0.0 2.8 2 1 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 EGO58435.1 - 0.0067 16.2 0.0 0.039 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGO58435.1 - 0.01 16.4 0.2 0.06 13.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGO58435.1 - 0.02 14.9 0.5 6.7 6.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 EGO58435.1 - 0.041 14.3 0.0 0.28 11.6 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EGO58435.1 - 0.058 13.5 0.0 0.82 9.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGO58435.1 - 0.064 13.6 0.0 0.21 12.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 EGO58435.1 - 0.11 12.7 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 EGO58435.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_29 PF13555.6 EGO58435.1 - 0.16 11.7 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SesA PF17107.5 EGO58435.1 - 0.19 12.0 2.3 1.8 8.8 0.6 2.8 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ACC_central PF08326.12 EGO58438.1 - 1.4e-285 949.2 0.0 1.8e-285 948.9 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EGO58438.1 - 4.1e-185 616.1 0.0 5.7e-185 615.7 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EGO58438.1 - 4.1e-52 176.7 0.0 1.1e-51 175.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGO58438.1 - 1.1e-27 96.7 0.1 2.9e-27 95.4 0.1 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGO58438.1 - 1.3e-21 76.7 0.0 3.2e-19 69.0 0.0 3.3 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGO58438.1 - 4.2e-17 61.7 0.1 9.4e-17 60.6 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGO58438.1 - 0.0027 17.3 0.0 0.0061 16.1 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EGO58438.1 - 0.0033 17.5 0.0 0.0096 16.0 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain GxGYxYP_N PF16216.5 EGO58438.1 - 0.0051 17.0 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal Biotin_lipoyl_2 PF13533.6 EGO58438.1 - 0.027 14.3 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 1 0 Biotin-lipoyl like ATPgrasp_Ter PF15632.6 EGO58438.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ANXA2R PF15721.5 EGO58439.1 - 0.078 13.5 0.1 0.15 12.5 0.1 1.5 1 1 0 1 1 1 0 Annexin-2 receptor Lipoprotein_21 PF14041.6 EGO58441.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 LppP/LprE lipoprotein Flp_Fap PF04964.14 EGO58443.1 - 0.036 13.9 1.0 0.074 12.9 1.0 1.5 1 0 0 1 1 1 0 Flp/Fap pilin component SEA PF01390.20 EGO58444.1 - 0.046 13.8 0.0 0.06 13.4 0.0 1.2 1 0 0 1 1 1 0 SEA domain AA_permease PF00324.21 EGO58446.1 - 1e-112 377.2 36.9 1.2e-112 376.9 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO58446.1 - 1.6e-33 116.2 40.8 2.1e-33 115.8 40.8 1.1 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_6 PF12697.7 EGO58448.1 - 6.7e-12 46.5 0.1 9.8e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGO58448.1 - 1.3e-09 38.1 0.1 3e-05 23.8 0.1 3.0 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO58448.1 - 2.1e-08 33.7 0.1 2.3e-07 30.4 0.2 2.2 2 1 0 2 2 2 1 Serine aminopeptidase, S33 HET PF06985.11 EGO58449.1 - 2.5e-23 83.1 0.0 1.3e-22 80.7 0.0 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Defensin_beta PF00711.19 EGO58449.1 - 0.0079 16.2 1.0 0.021 14.8 1.0 1.8 1 0 0 1 1 1 1 Beta defensin Myb_DNA-binding PF00249.31 EGO58450.1 - 0.028 14.6 0.4 0.075 13.2 0.1 1.9 2 1 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO58450.1 - 0.16 12.2 0.1 0.44 10.8 0.1 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain stn_TNFRSF12A PF12191.8 EGO58451.1 - 0.021 15.0 0.0 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain ETRAMP PF09716.10 EGO58451.1 - 0.035 14.1 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Pilin_N PF07790.11 EGO58451.1 - 3.2 8.7 7.0 0.34 11.9 0.9 2.5 3 0 0 3 3 3 0 Archaeal Type IV pilin, N-terminal SOG2 PF10428.9 EGO58452.1 - 0.0079 15.5 2.8 0.0079 15.5 2.8 1.6 2 0 0 2 2 2 1 RAM signalling pathway protein Shisa PF13908.6 EGO58452.1 - 0.14 12.4 0.2 0.28 11.4 0.2 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator F-box-like PF12937.7 EGO58457.1 - 0.004 17.0 0.0 0.0095 15.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like RE_HaeII PF09554.10 EGO58457.1 - 0.056 12.7 0.1 0.094 12.0 0.1 1.3 1 0 0 1 1 1 0 HaeII restriction endonuclease DUF1706 PF08020.11 EGO58458.1 - 0.058 13.3 0.2 0.22 11.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1706) Metallophos PF00149.28 EGO58459.1 - 2.1e-12 48.0 0.0 3.1e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGO58459.1 - 3.2e-08 33.9 0.0 5e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PLL PF18587.1 EGO58459.1 - 0.024 14.8 0.1 8.1 6.6 0.0 2.1 1 1 1 2 2 2 0 PTX/LNS-Like (PLL) domain Metallophos_3 PF14582.6 EGO58459.1 - 0.1 11.9 0.0 0.69 9.2 0.0 1.9 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily MPC PF03650.13 EGO58460.1 - 1.1e-34 118.9 0.0 1.4e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers SOG2 PF10428.9 EGO58461.1 - 0.00057 19.2 11.0 0.00067 19.0 11.0 1.0 1 0 0 1 1 1 1 RAM signalling pathway protein DUF4769 PF15992.5 EGO58461.1 - 0.0033 17.3 0.0 0.0039 17.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4769) IcmF-related PF06761.12 EGO58461.1 - 0.023 14.2 0.1 0.035 13.6 0.1 1.3 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing Vps5 PF09325.10 EGO58461.1 - 0.087 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Vps5 C terminal like Dicty_REP PF05086.12 EGO58461.1 - 0.38 8.7 2.9 0.36 8.7 2.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.13 EGO58461.1 - 1.3 8.9 4.5 1.5 8.8 4.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FSA_C PF10479.9 EGO58461.1 - 3.7 5.5 11.7 4.4 5.3 11.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SPX PF03105.19 EGO58461.1 - 5.9 6.7 7.9 8.1 6.2 7.9 1.2 1 0 0 1 1 1 0 SPX domain DUF4407 PF14362.6 EGO58462.1 - 0.15 11.4 0.8 0.27 10.6 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 EGO58462.1 - 0.3 11.4 1.1 1.2 9.5 0.1 2.1 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF2381 PF09544.10 EGO58462.1 - 0.33 10.5 3.7 0.13 11.7 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2381) ZapB PF06005.12 EGO58462.1 - 0.64 10.5 10.3 0.11 12.9 1.2 2.4 2 0 0 2 2 2 0 Cell division protein ZapB PRKG1_interact PF15898.5 EGO58462.1 - 2.6 9.0 7.0 7.3 7.6 7.0 1.6 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 EGO58462.1 - 5.7 6.8 7.2 2.4 8.0 0.2 2.4 1 1 1 2 2 2 0 Septum formation initiator Catalase PF00199.19 EGO58463.1 - 6.8e-173 575.2 0.3 8.7e-173 574.8 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGO58463.1 - 1e-20 73.7 0.0 2.2e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.24 EGO58463.1 - 3.1e-11 43.4 0.1 5.3e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 EGO58463.1 - 5.9e-10 39.0 0.6 1.2e-09 37.9 0.6 1.5 1 1 0 1 1 1 1 C-terminal domain found in long catalases Prok-E2_E PF14462.6 EGO58463.1 - 0.03 14.1 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic E2 family E SET PF00856.28 EGO58464.1 - 9.6e-07 29.3 0.0 4.4e-06 27.2 0.0 2.2 2 1 0 2 2 2 1 SET domain Phage-Gp8 PF09215.10 EGO58465.1 - 0.018 14.1 0.0 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage T4, Gp8 YkuI_C PF10388.9 EGO58465.1 - 0.027 14.3 0.3 0.041 13.7 0.3 1.3 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain DUF1308 PF07000.11 EGO58467.1 - 0.033 14.1 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) Abhydrolase_2 PF02230.16 EGO58470.1 - 0.00028 20.8 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 EGO58470.1 - 0.0055 16.2 1.0 0.037 13.5 0.2 2.1 1 1 1 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.20 EGO58470.1 - 0.044 13.4 0.3 3.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Putative esterase adh_short PF00106.25 EGO58471.1 - 2.6e-20 72.7 0.0 3.7e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO58471.1 - 1.2e-15 57.7 0.0 1.7e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO58471.1 - 5.3e-08 33.0 0.3 6.8e-08 32.6 0.3 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGO58471.1 - 0.0029 16.8 0.1 0.0084 15.3 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 EGO58471.1 - 0.069 13.2 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase I_LWEQ PF01608.17 EGO58471.1 - 0.084 13.1 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 I/LWEQ domain Glyco_hydro_35 PF01301.19 EGO58472.1 - 4.9e-18 65.8 0.0 5.4e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_49N PF17433.2 EGO58472.1 - 0.067 12.8 0.0 0.073 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain EHN PF06441.12 EGO58473.1 - 3e-30 104.8 0.1 4.9e-30 104.1 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EGO58473.1 - 4.9e-05 23.1 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_M24 PF00557.24 EGO58474.1 - 5.5e-59 199.4 0.1 8.9e-58 195.4 0.1 2.0 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.16 EGO58474.1 - 2.5e-24 85.3 0.0 5.4e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Aldo_ket_red PF00248.21 EGO58475.1 - 4.3e-55 187.0 0.0 4.9e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CBM_21 PF03370.13 EGO58478.1 - 5.4e-36 123.2 0.2 8.7e-36 122.5 0.2 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EGO58478.1 - 1.7e-12 47.7 0.7 3.4e-12 46.8 0.7 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) RSN1_7TM PF02714.15 EGO58484.1 - 5.6e-87 291.5 13.3 5.6e-87 291.5 13.3 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGO58484.1 - 2.2e-42 144.5 1.6 2.2e-42 144.5 1.6 2.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGO58484.1 - 3.6e-28 99.0 0.0 6.7e-28 98.1 0.0 1.5 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EGO58484.1 - 2.5e-17 62.8 0.0 7.1e-17 61.4 0.0 1.8 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 EGO58484.1 - 0.035 13.9 0.0 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) kleA_kleC PF17383.2 EGO58484.1 - 0.12 12.7 0.1 0.36 11.2 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Comm PF15957.5 EGO58485.1 - 2.4e-05 24.6 1.5 3.2e-05 24.2 1.0 1.4 1 1 0 1 1 1 1 Commissureless DUF4692 PF15763.5 EGO58485.1 - 0.013 16.0 1.6 0.013 16.0 1.6 1.5 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) DUF3481 PF11980.8 EGO58485.1 - 0.05 13.3 0.6 0.09 12.5 0.6 1.3 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein SARAF PF06682.12 EGO58485.1 - 1.7 8.2 8.6 3.2 7.3 8.5 1.5 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SR-25 PF10500.9 EGO58485.1 - 3.2 7.3 9.6 4.6 6.8 9.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SLX9 PF15341.6 EGO58487.1 - 0.24 11.8 4.1 0.13 12.7 1.5 1.8 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 Cyclin PF08613.11 EGO58488.1 - 3.1e-56 190.2 0.0 5.8e-56 189.3 0.0 1.5 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EGO58488.1 - 0.037 13.8 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF2457 PF10446.9 EGO58488.1 - 0.35 10.0 6.7 0.55 9.3 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TPP_enzyme_N PF02776.18 EGO58489.1 - 2.4e-37 128.2 0.3 1.1e-36 126.0 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGO58489.1 - 1.2e-22 80.4 0.0 2.4e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGO58489.1 - 1.9e-11 43.9 0.0 1.1e-10 41.4 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain NTP_transf_3 PF12804.7 EGO58489.1 - 0.042 14.2 0.0 0.79 10.1 0.0 2.7 2 1 0 2 2 2 0 MobA-like NTP transferase domain AAA_23 PF13476.6 EGO58489.1 - 0.65 10.5 5.1 1 9.8 5.1 1.2 1 0 0 1 1 1 0 AAA domain Nif11 PF07862.11 EGO58489.1 - 0.72 10.2 2.5 0.68 10.3 0.9 1.8 2 0 0 2 2 2 0 Nif11 domain U1snRNP70_N PF12220.8 EGO58489.1 - 0.82 10.4 4.6 1.6 9.5 4.6 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CHZ PF09649.10 EGO58490.1 - 0.014 14.9 0.6 0.028 13.9 0.6 1.6 1 0 0 1 1 1 0 Histone chaperone domain CHZ ADH_zinc_N_2 PF13602.6 EGO58491.1 - 4.8e-16 60.0 0.0 8e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGO58491.1 - 1.6e-15 57.2 0.0 3.3e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO58491.1 - 0.00075 19.3 0.0 0.0033 17.3 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 EGO58491.1 - 0.021 14.3 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EGO58491.1 - 0.052 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RIO1 PF01163.22 EGO58492.1 - 5.9e-71 238.0 0.5 1.3e-70 236.8 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EGO58492.1 - 0.00012 22.1 0.0 0.25 11.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGO58492.1 - 0.0053 16.1 0.7 0.073 12.4 0.2 2.5 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family CDC45 PF02724.14 EGO58492.1 - 0.017 13.5 12.4 0.018 13.3 12.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Pkinase_fungal PF17667.1 EGO58492.1 - 2.7 6.6 8.4 0.073 11.8 0.5 2.0 2 0 0 2 2 2 0 Fungal protein kinase APG17 PF04108.12 EGO58493.1 - 6.9e-128 427.1 0.2 7.8e-128 426.9 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 VbhA PF18495.1 EGO58496.1 - 0.056 13.3 0.3 4.3 7.3 0.1 2.4 2 0 0 2 2 2 0 Antitoxin VbhA Flavokinase PF01687.17 EGO58498.1 - 3e-11 43.6 0.0 5.1e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase ERG4_ERG24 PF01222.17 EGO58500.1 - 2.1e-204 679.2 3.3 2.4e-204 679.0 3.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGO58500.1 - 0.00014 21.5 0.5 0.00044 19.8 0.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.15 EGO58501.1 - 2.9e-17 62.6 0.0 7.5e-17 61.3 0.0 1.7 2 1 0 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EGO58501.1 - 2.7e-15 57.0 0.2 8.3e-15 55.4 0.0 1.9 3 0 0 3 3 3 1 Autophagy-related protein 27 CIMR PF00878.18 EGO58501.1 - 1.9e-06 28.0 0.3 1.7e-05 24.9 0.0 2.3 2 1 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat FAM176 PF14851.6 EGO58501.1 - 0.48 10.1 2.2 1.1 8.9 2.2 1.6 1 0 0 1 1 1 0 FAM176 family Glyco_hydro_61 PF03443.14 EGO58503.1 - 1.4e-62 211.3 0.2 2.3e-62 210.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EGO58503.1 - 5.4e-09 35.8 13.4 5.4e-09 35.8 13.4 2.7 2 1 0 2 2 2 1 Fungal cellulose binding domain SPATA25 PF15218.6 EGO58506.1 - 0.075 12.8 1.4 0.077 12.7 1.4 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 25 ADH_N PF08240.12 EGO58508.1 - 1.3e-09 37.8 0.1 3.3e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO58508.1 - 1e-05 25.5 0.1 2e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 EGO58508.1 - 0.082 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DciA PF05258.12 EGO58508.1 - 0.11 12.9 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Dna[CI] antecedent, DciA PAN_4 PF14295.6 EGO58509.1 - 8.6e-05 22.4 3.8 8.6e-05 22.4 3.8 1.9 2 0 0 2 2 2 1 PAN domain PAN_2 PF08276.11 EGO58509.1 - 0.51 10.5 4.6 0.33 11.1 1.9 2.1 2 0 0 2 2 2 0 PAN-like domain Glyco_hydro_3_C PF01915.22 EGO58510.1 - 7.3e-50 169.8 0.0 1.8e-49 168.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO58510.1 - 2.2e-35 122.5 0.0 3.6e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGO58510.1 - 5.2e-15 55.3 1.0 1.1e-14 54.3 1.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF892 PF05974.12 EGO58512.1 - 0.16 12.0 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF892) COesterase PF00135.28 EGO58513.1 - 1.1e-75 255.4 0.7 1.5e-75 255.0 0.7 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO58513.1 - 1.2e-05 25.3 0.6 4.6e-05 23.4 0.6 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold 2Fe-2S_Ferredox PF11591.8 EGO58514.1 - 0.039 13.8 1.0 4.8 7.1 0.1 2.5 2 0 0 2 2 2 0 Ferredoxin chloroplastic transit peptide p450 PF00067.22 EGO58516.1 - 3.5e-24 85.4 0.0 6.4e-17 61.4 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 FAD_binding_4 PF01565.23 EGO58517.1 - 7.5e-27 93.8 0.4 2e-26 92.4 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EGO58517.1 - 1.7e-05 24.8 1.5 3.3e-05 23.9 1.5 1.5 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 EGO58518.1 - 2.6e-32 112.2 0.6 4e-20 72.0 0.5 2.7 2 1 0 2 2 2 2 Cytochrome P450 IL32 PF15225.6 EGO58518.1 - 0.022 15.1 0.1 0.062 13.7 0.1 1.7 1 0 0 1 1 1 0 Interleukin 32 Methyltransf_2 PF00891.18 EGO58519.1 - 1.7e-22 79.8 0.0 2.8e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EGO58519.1 - 1.4e-06 28.9 0.0 8.9e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGO58519.1 - 0.00011 21.8 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGO58519.1 - 0.0078 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Receptor_IA-2 PF11548.8 EGO58519.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase receptor IA-2 Ubie_methyltran PF01209.18 EGO58519.1 - 0.015 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGO58519.1 - 0.031 15.0 0.0 0.081 13.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain HTH_28 PF13518.6 EGO58519.1 - 0.17 12.0 0.1 0.45 10.7 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain PS-DH PF14765.6 EGO58521.1 - 6.4e-78 262.0 0.0 1.1e-77 261.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 EGO58521.1 - 2.8e-68 230.3 0.0 7.3e-68 228.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EGO58521.1 - 6.5e-59 198.8 0.4 1.7e-58 197.5 0.2 1.9 2 0 0 2 2 1 1 KR domain Acyl_transf_1 PF00698.21 EGO58521.1 - 1.2e-51 176.1 0.5 2.8e-51 174.9 0.5 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGO58521.1 - 1.4e-35 121.8 0.0 6.9e-35 119.6 0.0 2.3 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EGO58521.1 - 3.6e-21 75.8 0.0 7.5e-20 71.5 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGO58521.1 - 1.5e-17 64.1 0.3 1.1e-15 58.0 0.1 3.5 3 1 0 3 3 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 EGO58521.1 - 2.5e-14 53.5 0.0 1.8e-13 50.7 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO58521.1 - 1e-12 48.5 0.0 6e-12 46.1 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO58521.1 - 7.9e-12 45.7 0.0 3.9e-11 43.4 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EGO58521.1 - 1.3e-11 44.4 0.1 3.6e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_31 PF13847.6 EGO58521.1 - 1.8e-11 44.0 0.0 9.3e-11 41.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 EGO58521.1 - 1.3e-08 34.9 0.2 6.1e-07 29.5 0.1 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EGO58521.1 - 1.2e-07 31.9 0.3 3.5e-07 30.5 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 EGO58521.1 - 6.4e-06 25.7 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.19 EGO58521.1 - 1.2e-05 24.5 0.0 2.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N_2 PF13602.6 EGO58521.1 - 2e-05 25.7 0.0 0.026 15.6 0.0 3.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 EGO58521.1 - 2.2e-05 24.1 0.0 5.6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 EGO58521.1 - 7.2e-05 22.1 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Thiolase_N PF00108.23 EGO58521.1 - 0.00068 19.1 1.7 0.00098 18.6 0.3 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_N PF08240.12 EGO58521.1 - 0.00068 19.5 0.3 0.0016 18.3 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.10 EGO58521.1 - 0.0043 16.9 0.2 0.011 15.6 0.2 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_2 PF00891.18 EGO58521.1 - 0.0047 16.2 0.1 0.015 14.6 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain AATase PF07247.12 EGO58522.1 - 4e-14 52.1 0.0 1.1e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.20 EGO58522.1 - 0.18 10.4 0.4 7.6 5.1 0.1 2.1 2 0 0 2 2 2 0 Condensation domain MFS_1 PF07690.16 EGO58523.1 - 6.1e-39 133.9 53.8 1.8e-37 129.1 53.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO58523.1 - 1.1e-12 47.2 12.4 1.1e-12 47.2 12.4 2.2 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_6 PF07332.11 EGO58523.1 - 0.1 12.6 0.3 0.1 12.6 0.3 5.6 5 2 1 6 6 6 0 Putative Actinobacterial Holin-X, holin superfamily III DUF412 PF04217.13 EGO58523.1 - 3.1 7.7 4.5 19 5.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF412 Fungal_trans PF04082.18 EGO58524.1 - 2.6e-05 23.4 0.0 4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 EGO58525.1 - 2.3e-29 102.3 0.0 3.4e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO58525.1 - 1.2e-22 80.7 0.0 1.6e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO58525.1 - 2.3e-07 30.9 0.0 3.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO58525.1 - 9.4e-07 28.5 0.1 3.2e-06 26.8 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGO58525.1 - 2.2e-06 27.7 0.0 5.1e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding DFP PF04127.15 EGO58525.1 - 0.044 13.6 0.1 0.07 13.0 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein GDP_Man_Dehyd PF16363.5 EGO58525.1 - 0.09 12.2 0.0 0.53 9.6 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGO58525.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sulfate_transp PF00916.20 EGO58526.1 - 4.5e-78 262.7 7.7 6.8e-78 262.1 7.7 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGO58526.1 - 6.9e-18 64.4 0.0 1.4e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EGO58526.1 - 0.0003 21.1 0.0 0.00078 19.7 0.0 1.7 1 1 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EGO58526.1 - 0.0085 16.5 3.4 0.0085 16.5 3.4 2.4 2 0 0 2 2 2 1 Molybdate transporter of MFS superfamily DUF4166 PF13761.6 EGO58526.1 - 0.033 14.0 0.1 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4166) DUF1286 PF06939.11 EGO58526.1 - 0.06 13.6 3.0 3.5 7.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1286) EF-hand_7 PF13499.6 EGO58527.1 - 1.1e-05 25.8 0.1 1.3e-05 25.5 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGO58527.1 - 1.9e-05 23.8 0.0 0.015 14.8 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGO58527.1 - 0.00028 20.6 0.0 0.031 14.2 0.0 2.9 1 1 1 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 EGO58527.1 - 0.024 14.6 0.1 0.078 12.9 0.0 1.7 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.6 EGO58527.1 - 0.039 13.8 0.1 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 EGO58527.1 - 0.06 12.9 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 EF hand CTP_transf_1 PF01148.20 EGO58528.1 - 7.3e-79 265.3 25.7 9.2e-79 264.9 25.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.8 EGO58529.1 - 2.6e-42 144.2 0.0 1.8e-24 86.3 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3636) FAM76 PF16046.5 EGO58529.1 - 0.0055 16.1 1.2 0.0097 15.3 1.2 1.3 1 0 0 1 1 1 1 FAM76 protein Mei5 PF10376.9 EGO58529.1 - 0.047 13.5 2.8 0.078 12.8 2.8 1.2 1 0 0 1 1 1 0 Double-strand recombination repair protein Uso1_p115_C PF04871.13 EGO58529.1 - 0.13 12.6 11.7 0.35 11.2 11.7 1.7 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region EMP24_GP25L PF01105.24 EGO58529.1 - 0.39 10.6 0.9 0.78 9.7 0.9 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SOGA PF11365.8 EGO58529.1 - 0.52 11.5 5.9 1.1 10.4 5.9 1.5 1 0 0 1 1 1 0 Protein SOGA DUF4407 PF14362.6 EGO58529.1 - 0.66 9.3 5.4 1.4 8.2 5.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 EGO58529.1 - 1.2 7.6 6.9 1.9 7.0 6.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Macoilin PF09726.9 EGO58529.1 - 1.4 7.4 8.2 2.2 6.7 8.2 1.2 1 0 0 1 1 1 0 Macoilin family DUF3584 PF12128.8 EGO58529.1 - 1.4 6.3 8.3 2.2 5.7 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Thiolase_N PF00108.23 EGO58531.1 - 2.1e-68 230.5 0.6 2.7e-68 230.2 0.6 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGO58531.1 - 3.1e-41 139.9 0.2 7.9e-41 138.6 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGO58531.1 - 0.041 13.5 1.2 0.14 11.7 1.1 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 EGO58531.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Glyco_hydro_cc PF11790.8 EGO58532.1 - 2.1e-73 246.8 0.3 2.5e-73 246.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Aldedh PF00171.22 EGO58533.1 - 1.6e-142 475.3 0.0 1.9e-142 475.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Metallophos PF00149.28 EGO58534.1 - 4.8e-20 72.9 0.4 8e-20 72.2 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EGO58534.1 - 6.4e-18 65.4 1.8 1.1e-17 64.6 0.2 2.3 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EGO58534.1 - 3e-16 59.8 2.3 6.9e-16 58.6 2.3 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 EGO58534.1 - 0.0093 16.5 0.1 0.021 15.4 0.1 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain SMP PF04927.12 EGO58535.1 - 0.0072 16.8 0.2 0.011 16.2 0.2 1.2 1 0 0 1 1 1 1 Seed maturation protein Kelch_5 PF13854.6 EGO58536.1 - 3.4e-12 46.1 7.8 2.9e-11 43.1 0.2 4.5 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 EGO58536.1 - 0.0014 18.6 19.8 0.4 10.7 0.1 6.6 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EGO58536.1 - 0.0099 16.1 11.9 6.3 7.2 0.1 6.0 5 2 1 6 6 6 2 Kelch motif Kelch_3 PF13415.6 EGO58536.1 - 0.024 14.9 0.3 0.024 14.9 0.3 6.3 7 2 0 7 7 7 0 Galactose oxidase, central domain Kelch_2 PF07646.15 EGO58536.1 - 0.06 13.4 9.0 4.6 7.4 0.1 6.0 6 0 0 6 6 6 0 Kelch motif PTP_tm PF18861.1 EGO58536.1 - 0.22 11.5 1.8 0.38 10.7 1.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Kelch_1 PF01344.25 EGO58536.1 - 1 9.0 0.0 1 9.0 0.0 5.8 8 0 0 8 8 8 0 Kelch motif Glyco_hydro_43 PF04616.14 EGO58537.1 - 2e-104 349.0 2.2 3.2e-104 348.3 2.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EGO58537.1 - 3e-40 138.1 0.0 5e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_32N PF00251.20 EGO58537.1 - 0.0059 16.2 0.2 0.016 14.8 0.2 1.7 1 1 1 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Prok-RING_2 PF14445.6 EGO58537.1 - 0.079 13.1 0.2 0.25 11.5 0.2 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 YhhN PF07947.14 EGO58538.1 - 1.5e-38 132.3 14.5 2.3e-38 131.6 14.5 1.3 1 0 0 1 1 1 1 YhhN family MFS_1 PF07690.16 EGO58540.1 - 6.6e-32 110.8 28.0 8.7e-32 110.4 28.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO58540.1 - 5e-06 25.7 19.0 8.6e-05 21.6 18.9 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter PI-PLC-X PF00388.19 EGO58541.1 - 1.3e-50 170.8 0.0 2.1e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGO58541.1 - 5e-38 130.0 0.0 9.3e-38 129.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EGO58541.1 - 0.0036 17.5 0.0 0.026 14.8 0.0 2.3 1 1 0 1 1 1 1 C2 domain Zip PF02535.22 EGO58542.1 - 9.5e-47 159.8 0.2 1.9e-46 158.9 0.2 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4231 PF14015.6 EGO58542.1 - 0.23 12.0 4.5 21 5.6 0.1 3.7 3 2 0 3 3 3 0 Protein of unknown function (DUF4231) PsbH PF00737.20 EGO58542.1 - 0.84 9.4 4.7 14 5.5 0.4 2.7 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein DUF3357 PF11837.8 EGO58542.1 - 7.2 7.1 5.8 7.6 7.0 0.3 3.6 4 1 1 5 5 5 0 Domain of unknown function (DUF3357) 5_nucleotid_C PF02872.18 EGO58543.1 - 2.8e-37 128.4 0.1 5.9e-37 127.3 0.1 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGO58543.1 - 1.6e-11 45.1 0.6 1.9e-10 41.6 0.1 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.6 EGO58543.1 - 0.00065 19.1 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 YmdB-like protein Hce2 PF14856.6 EGO58544.1 - 5.2e-15 55.6 0.4 1.5e-14 54.1 0.4 1.7 1 1 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor TPR_2 PF07719.17 EGO58545.1 - 3e-10 39.4 9.3 0.0005 20.0 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGO58545.1 - 1.6e-07 30.9 4.0 0.0099 15.7 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO58545.1 - 0.00055 19.9 2.2 0.042 14.1 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO58545.1 - 0.0044 17.3 0.1 0.0044 17.3 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGO58545.1 - 0.01 16.6 9.1 0.18 12.7 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGO58545.1 - 0.017 15.7 0.1 0.017 15.7 0.1 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGO58545.1 - 0.028 14.1 0.0 1.9 8.2 0.0 3.4 2 1 1 3 3 3 0 TPR repeat TPR_7 PF13176.6 EGO58545.1 - 0.076 13.1 1.2 0.3 11.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGO58545.1 - 0.19 12.3 1.5 12 6.5 0.0 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat GYF PF02213.16 EGO58546.1 - 7.3e-18 64.0 0.4 1.5e-17 63.0 0.4 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EGO58546.1 - 0.016 15.0 0.0 0.051 13.4 0.0 1.9 1 0 0 1 1 1 0 GYF domain 2 SnoaL_2 PF12680.7 EGO58547.1 - 0.0003 21.4 0.1 0.00071 20.2 0.1 1.6 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EGO58547.1 - 0.0004 20.2 0.0 0.00089 19.1 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF2612 PF11041.8 EGO58547.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) Cutinase PF01083.22 EGO58549.1 - 1.1e-53 181.8 0.2 1.5e-53 181.4 0.2 1.2 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 EGO58549.1 - 0.092 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Cutinase PF01083.22 EGO58550.1 - 5.4e-58 195.9 7.6 6.2e-58 195.7 7.6 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EGO58550.1 - 2.4e-06 27.3 0.1 3.4e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 EGO58550.1 - 0.0091 15.7 0.1 0.016 14.9 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO58550.1 - 0.014 16.0 0.1 0.016 15.8 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 EGO58550.1 - 0.23 10.9 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Marek_A PF02124.15 EGO58552.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Marek's disease glycoprotein A TRAP_alpha PF03896.16 EGO58553.1 - 0.0082 15.4 0.2 0.013 14.7 0.2 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Trp_oprn_chp PF09534.10 EGO58554.1 - 0.0039 17.0 3.3 0.96 9.2 0.0 2.9 2 0 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4366 PF14283.6 EGO58554.1 - 0.023 14.7 3.8 15 5.6 4.2 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4366) SKG6 PF08693.10 EGO58554.1 - 0.065 12.6 0.4 0.19 11.2 0.4 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain THEG4 PF15834.5 EGO58554.1 - 0.17 11.9 0.6 1.1 9.2 0.2 2.5 2 0 0 2 2 2 0 Testis highly expressed protein 4 Herpes_UL74 PF07982.12 EGO58554.1 - 0.3 10.0 2.6 0.51 9.2 2.6 1.3 1 0 0 1 1 1 0 Herpes UL74 glycoproteins CDH-cyt PF16010.5 EGO58555.1 - 1.9e-34 118.9 0.4 3.3e-34 118.2 0.4 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase SDA1 PF05285.12 EGO58555.1 - 7.4 5.9 15.2 0.25 10.8 9.5 1.4 2 0 0 2 2 2 0 SDA1 FYVE PF01363.21 EGO58556.1 - 1.6e-21 76.2 22.2 1.6e-16 60.2 4.4 3.1 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 EGO58556.1 - 6.3e-18 64.2 6.7 1.6e-17 62.9 6.7 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 EGO58556.1 - 0.00027 21.0 3.3 0.00027 21.0 3.3 3.7 3 1 1 4 4 4 1 AN1-like Zinc finger zf-Di19 PF05605.12 EGO58556.1 - 0.078 13.3 0.1 0.078 13.3 0.1 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 EGO58556.1 - 0.12 12.8 6.4 0.54 10.7 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EGO58556.1 - 0.17 12.8 28.8 0.63 11.0 0.0 6.0 5 1 1 6 6 5 0 C2H2-type zinc finger DUF2730 PF10805.8 EGO58556.1 - 0.18 11.9 1.4 9 6.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) zf-C2H2_12 PF18658.1 EGO58556.1 - 0.22 11.1 0.0 0.22 11.1 0.0 2.5 3 0 0 3 3 3 0 Zinc-finger C2H2-type zf-C2H2_2 PF12756.7 EGO58556.1 - 0.37 11.2 9.6 1.1 9.6 0.0 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) UBZ_FAAP20 PF15750.5 EGO58556.1 - 0.45 10.5 1.9 21 5.2 0.3 2.9 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger DUF1192 PF06698.11 EGO58556.1 - 1.7 8.7 5.5 2.2 8.4 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) zf-C2HC5 PF06221.13 EGO58556.1 - 2.5 8.2 18.6 5.5 7.1 0.4 4.7 4 1 1 5 5 5 0 Putative zinc finger motif, C2HC5-type HypA PF01155.19 EGO58556.1 - 7.9 6.6 14.3 0.84 9.7 0.4 4.1 3 1 1 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NAD_binding_7 PF13241.6 EGO58557.1 - 1.1e-27 96.5 0.0 1.8e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EGO58557.1 - 2e-25 88.2 1.0 4.8e-25 87.0 1.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EGO58557.1 - 4.6e-14 51.6 0.2 9.5e-14 50.5 0.2 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NCD2 PF04905.13 EGO58557.1 - 0.051 13.6 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) Sina PF03145.16 EGO58558.1 - 0.00012 22.1 26.9 0.077 12.9 0.9 4.8 1 1 4 5 5 5 3 Seven in absentia protein family DUF1644 PF07800.12 EGO58558.1 - 0.00035 20.7 21.9 0.086 12.9 0.8 5.3 1 1 3 5 5 5 3 Protein of unknown function (DUF1644) Hairy_orange PF07527.13 EGO58558.1 - 0.0021 18.2 0.3 3.4 7.9 0.0 3.0 3 0 0 3 3 3 2 Hairy Orange RNA_pol_3_Rpc31 PF11705.8 EGO58558.1 - 0.0095 16.2 1.5 0.013 15.7 1.5 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 zf-H2C2_5 PF13909.6 EGO58558.1 - 0.04 13.7 23.7 3 7.7 0.1 6.8 6 1 0 6 6 6 0 C2H2-type zinc-finger domain OrsD PF12013.8 EGO58558.1 - 0.33 11.4 20.7 1.6 9.2 0.5 5.0 3 2 1 4 4 4 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-A20 PF01754.16 EGO58558.1 - 0.73 9.8 6.5 0.9 9.6 0.2 3.4 3 0 0 3 3 3 0 A20-like zinc finger Ank_4 PF13637.6 EGO58559.1 - 4.6e-13 49.4 2.6 1.3e-08 35.2 0.4 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO58559.1 - 4.9e-13 49.5 0.1 5.2e-05 23.8 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EGO58559.1 - 9.7e-11 41.6 3.1 0.059 13.9 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EGO58559.1 - 4.6e-10 38.9 0.6 0.013 15.9 0.0 5.0 5 0 0 5 5 4 2 Ankyrin repeat Ank_5 PF13857.6 EGO58559.1 - 7.3e-08 32.5 3.7 0.0022 18.2 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) KilA-N PF04383.13 EGO58559.1 - 7.1e-06 25.9 0.3 4.7e-05 23.2 0.3 2.2 1 1 0 1 1 1 1 KilA-N domain TMF_DNA_bd PF12329.8 EGO58559.1 - 0.057 13.4 13.9 0.26 11.3 7.8 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Exonuc_VII_L PF02601.15 EGO58559.1 - 0.29 10.6 5.4 0.68 9.4 5.4 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4404 PF14357.6 EGO58559.1 - 0.67 10.6 3.7 2.3 8.9 3.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) BLOC1_2 PF10046.9 EGO58559.1 - 0.8 10.0 4.7 0.95 9.8 2.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 USP8_interact PF08941.10 EGO58559.1 - 4.8 6.9 6.2 2 8.2 2.6 2.1 2 0 0 2 2 2 0 USP8 interacting DUF16 PF01519.16 EGO58559.1 - 5.3 7.6 8.0 1.4 9.4 3.7 2.3 3 0 0 3 3 2 0 Protein of unknown function DUF16 HAUS6_N PF14661.6 EGO58559.1 - 8.5 5.9 7.7 5.4 6.5 3.1 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Complex1_LYR PF05347.15 EGO58560.1 - 2.7e-07 30.5 1.1 7.5e-07 29.1 0.4 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGO58560.1 - 0.0046 17.7 0.7 0.0046 17.7 0.7 2.4 3 1 0 3 3 3 1 Complex1_LYR-like Acetyltransf_1 PF00583.25 EGO58561.1 - 5.7e-14 52.3 0.0 1.1e-13 51.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO58561.1 - 1.2e-06 28.9 0.0 2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO58561.1 - 1.5e-05 24.9 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EGO58561.1 - 0.0002 21.3 0.0 0.0003 20.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGO58561.1 - 0.012 16.3 0.0 0.018 15.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGO58561.1 - 0.12 12.5 0.0 1 9.5 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_16 PF05301.11 EGO58561.1 - 0.19 11.5 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 5_nucleotid_C PF02872.18 EGO58562.1 - 5.6e-41 140.4 0.0 9.1e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGO58562.1 - 6.3e-08 33.4 0.1 9.4e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YmdB PF13277.6 EGO58562.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 YmdB-like protein CENP-L PF13092.6 EGO58563.1 - 1.8e-57 194.1 0.0 4.5e-57 192.8 0.0 1.7 2 0 0 2 2 2 1 Kinetochore complex Sim4 subunit Fta1 DUF3740 PF12548.8 EGO58565.1 - 0.18 12.2 2.5 0.16 12.4 0.2 2.0 2 0 0 2 2 2 0 Sulfatase protein zf-C2H2_4 PF13894.6 EGO58565.1 - 0.61 11.1 15.4 1 10.4 0.2 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger HET PF06985.11 EGO58568.1 - 4.1e-23 82.4 7.4 1.1e-21 77.7 0.0 3.1 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Beta_elim_lyase PF01212.21 EGO58568.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Abhydrolase_3 PF07859.13 EGO58569.1 - 3.2e-24 86.0 0.1 7.2e-24 84.8 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO58569.1 - 1e-14 54.2 0.0 1.7e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EGO58569.1 - 0.027 14.0 0.0 0.059 12.8 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family GbpA_2 PF18416.1 EGO58569.1 - 0.039 14.2 0.1 0.079 13.3 0.1 1.5 1 0 0 1 1 1 0 N-acetylglucosamine binding protein domain 2 Abhydrolase_6 PF12697.7 EGO58569.1 - 0.083 13.5 2.8 0.062 13.9 0.6 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Aminotran_5 PF00266.19 EGO58570.1 - 1.4e-20 73.6 0.0 5e-20 71.8 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGO58570.1 - 0.00074 18.8 0.0 0.003 16.8 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II SepSecS PF05889.13 EGO58570.1 - 0.11 11.1 0.1 0.21 10.3 0.1 1.4 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Epimerase PF01370.21 EGO58571.1 - 1.9e-09 37.4 0.0 2.7e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGO58571.1 - 7.6e-09 35.1 0.0 3.2e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EGO58571.1 - 1.1e-06 28.4 0.0 1.9e-06 27.5 0.0 1.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EGO58571.1 - 3.1e-06 27.2 0.0 5.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EGO58571.1 - 6.9e-05 22.4 0.5 0.00013 21.5 0.1 1.8 2 1 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.19 EGO58571.1 - 0.0021 17.1 0.0 0.0038 16.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EGO58571.1 - 0.022 14.7 0.1 0.042 13.7 0.0 1.5 2 0 0 2 2 2 0 NAD(P)H-binding Shikimate_DH PF01488.20 EGO58571.1 - 0.072 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 EGO58571.1 - 0.08 12.1 0.0 0.098 11.8 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.13 EGO58571.1 - 0.098 12.2 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family FAD_binding_3 PF01494.19 EGO58572.1 - 3.9e-15 56.0 1.8 5.1e-13 49.0 1.8 2.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGO58572.1 - 3e-05 23.8 2.7 8.1e-05 22.3 1.7 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGO58572.1 - 0.00075 20.0 0.7 0.011 16.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO58572.1 - 0.0029 17.8 0.1 0.0088 16.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO58572.1 - 0.0062 15.8 0.0 0.074 12.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EGO58572.1 - 0.024 13.7 0.0 4.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.14 EGO58572.1 - 0.058 12.2 0.1 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase DUF4636 PF15468.6 EGO58573.1 - 0.49 10.1 3.2 1.4 8.5 1.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4636) YebO PF13974.6 EGO58573.1 - 2 8.6 5.7 4.4 7.4 5.7 1.5 1 0 0 1 1 1 0 YebO-like protein XAP5 PF04921.14 EGO58578.1 - 4.7e-94 314.9 0.3 9.8e-94 313.8 0.3 1.5 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 EGO58578.1 - 5 7.5 24.5 0.062 13.7 5.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4604) Methyltransf_10 PF05971.12 EGO58579.1 - 1.7e-61 208.2 0.0 2.6e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 EGO58579.1 - 0.0038 16.8 0.0 0.012 15.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGO58579.1 - 0.0039 16.6 0.0 0.0066 15.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DAPG_hydrolase PF18089.1 EGO58579.1 - 0.021 14.4 0.5 0.049 13.2 0.3 1.6 2 0 0 2 2 2 0 DAPG hydrolase PhiG domain Methyltransf_18 PF12847.7 EGO58579.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UBM PF14377.6 EGO58580.1 - 9.2e-09 34.5 11.6 6.8e-07 28.5 1.3 3.7 3 0 0 3 3 3 2 Ubiquitin binding region PKD_channel PF08016.12 EGO58581.1 - 6.4e-07 28.4 16.6 9.6e-06 24.5 16.6 2.1 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EGO58581.1 - 0.011 15.0 25.8 0.14 11.4 25.8 2.1 1 1 0 1 1 1 0 Ion transport protein UPF0542 PF15086.6 EGO58581.1 - 0.038 13.9 0.0 0.17 11.8 0.0 2.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Vasculin PF15337.6 EGO58581.1 - 0.32 11.9 4.2 0.63 10.9 4.2 1.5 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 Sugar_tr PF00083.24 EGO58582.1 - 2e-34 119.3 12.2 2.3e-34 119.0 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO58582.1 - 4.4e-07 29.2 16.6 4.5e-06 25.8 11.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Gate PF07670.14 EGO58582.1 - 0.57 10.5 6.3 0.5 10.7 4.3 1.9 1 1 1 2 2 2 0 Nucleoside recognition Fungal_trans PF04082.18 EGO58583.1 - 5.8e-09 35.4 0.0 9.3e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO58583.1 - 7.9e-06 25.9 7.2 1.6e-05 24.9 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 EGO58584.1 - 6.2e-39 134.1 23.3 1.9e-38 132.5 23.3 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO58584.1 - 1.2e-29 103.4 52.9 7.8e-29 100.7 31.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Rib_5-P_isom_A PF06026.14 EGO58585.1 - 1.3e-45 155.1 0.0 2e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) MFS_1 PF07690.16 EGO58586.1 - 3.2e-19 69.1 15.7 4.6e-19 68.6 15.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CBM_2 PF00553.19 EGO58586.1 - 0.059 13.7 0.2 0.13 12.6 0.2 1.5 1 0 0 1 1 1 0 Cellulose binding domain DUF4500 PF14937.6 EGO58586.1 - 0.14 12.2 0.1 0.42 10.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) TauD PF02668.16 EGO58587.1 - 4.1e-44 151.4 0.4 5.8e-44 150.9 0.4 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UL16 PF17622.2 EGO58587.1 - 0.0071 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Viral unique long protein 16 Plasmod_MYXSPDY PF07981.11 EGO58587.1 - 0.029 14.3 0.2 0.056 13.4 0.2 1.4 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY Porphobil_deamC PF03900.15 EGO58592.1 - 0.014 15.8 0.1 0.025 15.0 0.1 1.3 1 0 0 1 1 1 0 Porphobilinogen deaminase, C-terminal domain Dodecin PF07311.12 EGO58595.1 - 8.9 6.7 7.8 0.36 11.1 0.7 2.4 2 0 0 2 2 2 0 Dodecin FAD_binding_4 PF01565.23 EGO58597.1 - 8.2e-22 77.4 1.2 3.7e-21 75.3 0.3 2.6 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 EGO58597.1 - 1.8e-14 53.5 0.0 4.2e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 EGO58598.1 - 2.1e-23 82.8 30.9 6.2e-23 81.3 30.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EGO58598.1 - 7.7e-06 25.4 1.2 7.7e-06 25.4 1.2 2.7 2 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Zip PF02535.22 EGO58599.1 - 3e-60 204.2 0.9 3.5e-60 204.0 0.9 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2157 PF09925.9 EGO58599.1 - 0.033 14.0 3.4 7.3 6.4 0.0 3.4 3 2 0 3 3 3 0 Predicted membrane protein (DUF2157) RhoGAP PF00620.27 EGO58600.1 - 3.3e-11 43.2 0.0 4.9e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Aminotran_3 PF00202.21 EGO58602.1 - 3.7e-77 259.7 0.0 1.9e-56 191.5 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-III SIR2 PF02146.17 EGO58603.1 - 7.3e-29 100.9 0.1 7e-21 74.9 0.0 2.2 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 EGO58603.1 - 0.013 15.2 0.0 4.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain TFIIA PF03153.13 EGO58604.1 - 0.0029 17.7 42.8 0.0048 17.0 42.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2347 PF09804.9 EGO58604.1 - 3.1 7.3 12.7 4.3 6.8 12.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Neur_chan_memb PF02932.16 EGO58604.1 - 3.7 7.5 9.8 5.4 7.0 9.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Exonuc_VII_L PF02601.15 EGO58604.1 - 8.5 5.9 17.7 13 5.3 17.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit BORG_CEP PF14957.6 EGO58604.1 - 9.7 7.4 7.6 21 6.3 7.6 1.6 1 0 0 1 1 1 0 Cdc42 effector AAA_18 PF13238.6 EGO58605.1 - 7.1e-08 33.1 0.0 1.9e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO58605.1 - 4.5e-07 30.1 0.0 7.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 EGO58605.1 - 2.1e-06 27.9 0.0 0.0039 17.3 0.0 2.2 2 0 0 2 2 2 2 Shikimate kinase Rad17 PF03215.15 EGO58605.1 - 0.00017 21.5 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 EGO58605.1 - 0.00041 20.8 0.0 0.0012 19.3 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 EGO58605.1 - 0.00076 19.3 0.0 0.0032 17.2 0.0 1.9 2 0 0 2 2 2 1 Cytidylate kinase ATPase_2 PF01637.18 EGO58605.1 - 0.0011 19.0 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_17 PF13207.6 EGO58605.1 - 0.0012 19.3 0.0 0.15 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 EGO58605.1 - 0.0021 17.9 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_14 PF13173.6 EGO58605.1 - 0.003 17.6 0.0 0.0055 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO58605.1 - 0.0041 17.5 0.0 0.0055 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 EGO58605.1 - 0.0076 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EGO58605.1 - 0.012 14.9 0.0 0.037 13.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 EGO58605.1 - 0.013 15.7 0.1 0.051 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EGO58605.1 - 0.013 15.3 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_22 PF13401.6 EGO58605.1 - 0.014 15.7 0.0 0.027 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.6 EGO58605.1 - 0.018 15.2 0.0 0.083 13.0 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase-like family T2SSE PF00437.20 EGO58605.1 - 0.025 13.7 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Parvo_NS1 PF01057.17 EGO58605.1 - 0.054 12.6 0.1 0.074 12.1 0.1 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 EGO58605.1 - 0.056 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 EGO58605.1 - 0.11 12.4 0.1 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 NTPase CoaE PF01121.20 EGO58605.1 - 0.11 12.1 0.0 0.94 9.1 0.0 2.0 2 0 0 2 2 2 0 Dephospho-CoA kinase ABC_tran PF00005.27 EGO58605.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 EGO58605.1 - 0.15 12.6 0.1 0.25 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EGO58605.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 EGO58605.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Glycophorin_A PF01102.18 EGO58606.1 - 0.0028 17.9 1.0 0.0081 16.4 0.1 2.3 3 1 0 3 3 3 1 Glycophorin A Tape_meas_lam_C PF09718.10 EGO58606.1 - 0.0063 16.6 4.7 10 6.4 0.6 3.9 1 1 1 3 3 3 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Perilipin PF03036.16 EGO58606.1 - 0.0083 15.2 4.6 0.0083 15.2 4.6 2.2 1 1 1 2 2 2 1 Perilipin family VWA_N PF08399.11 EGO58606.1 - 0.017 15.6 0.2 0.039 14.4 0.2 1.5 1 0 0 1 1 1 0 VWA N-terminal MAS20 PF02064.15 EGO58606.1 - 0.021 14.9 2.6 0.021 14.9 2.6 1.7 2 0 0 2 2 2 0 MAS20 protein import receptor Nucleoside_tran PF01733.18 EGO58606.1 - 0.052 12.9 0.5 0.078 12.4 0.5 1.2 1 0 0 1 1 1 0 Nucleoside transporter YMF19 PF02326.15 EGO58606.1 - 0.08 13.7 0.5 0.16 12.8 0.5 1.6 1 0 0 1 1 1 0 Plant ATP synthase F0 Connexin PF00029.19 EGO58606.1 - 0.11 12.3 0.9 0.16 11.7 0.9 1.2 1 0 0 1 1 1 0 Connexin Sre PF03125.18 EGO58606.1 - 0.11 11.7 0.7 0.16 11.1 0.7 1.2 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor Fe_bilin_red PF05996.12 EGO58606.1 - 0.11 12.2 1.6 0.18 11.5 1.6 1.2 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase EMC3_TMCO1 PF01956.16 EGO58606.1 - 0.13 12.0 8.5 0.25 11.1 8.5 1.7 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF5341 PF17276.2 EGO58606.1 - 0.17 12.1 0.6 0.37 11.0 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5341) TMEM208_SND2 PF05620.11 EGO58606.1 - 0.24 11.2 1.5 0.41 10.4 1.5 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Phage_holin_7_1 PF16081.5 EGO58606.1 - 0.63 10.2 3.2 1.5 9.0 2.0 1.9 1 1 1 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family MIF4G_like_2 PF09090.11 EGO58606.1 - 1.6 8.1 7.0 2.2 7.7 6.0 1.6 1 1 0 1 1 1 0 MIF4G like NEMP PF10225.9 EGO58606.1 - 7.9 6.1 5.9 1 9.0 1.5 1.6 2 0 0 2 2 2 0 NEMP family DUF4131 PF13567.6 EGO58608.1 - 0.27 10.9 1.7 1.1 8.9 0.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) PhoR PF11808.8 EGO58608.1 - 0.27 11.7 1.5 4.2 7.9 0.3 2.3 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Exonuc_VII_L PF02601.15 EGO58608.1 - 0.88 9.1 6.0 1.1 8.8 6.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SoDot-IcmSS PF16848.5 EGO58610.1 - 0.063 13.3 0.7 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Substrate of the Dot/Icm secretion system, putative CDC45 PF02724.14 EGO58614.1 - 0.03 12.6 1.0 0.05 11.9 1.0 1.4 1 0 0 1 1 1 0 CDC45-like protein SGS PF05002.15 EGO58614.1 - 0.07 13.3 0.6 3.7 7.7 0.6 3.0 2 0 0 2 2 2 0 SGS domain DUF2057 PF09829.9 EGO58615.1 - 0.022 14.9 0.8 0.049 13.8 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Pentapeptide PF00805.22 EGO58621.1 - 0.00031 20.3 5.7 0.0006 19.4 2.6 2.6 2 1 0 2 2 2 1 Pentapeptide repeats (8 copies) GRP PF07172.11 EGO58624.1 - 0.00014 22.5 14.7 0.00017 22.2 14.7 1.3 1 0 0 1 1 1 1 Glycine rich protein family Fip1 PF05182.13 EGO58629.1 - 3e-20 71.5 1.2 5.2e-20 70.7 1.2 1.4 1 0 0 1 1 1 1 Fip1 motif Ebola_NP PF05505.12 EGO58629.1 - 0.32 9.3 7.0 0.45 8.8 7.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Med13_C PF06333.12 EGO58629.1 - 1.9 7.7 8.7 2.5 7.3 8.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain ORC6 PF05460.13 EGO58629.1 - 2.9 7.1 8.4 4.3 6.5 8.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TMEM154 PF15102.6 EGO58629.1 - 6.8 6.6 7.3 13 5.7 7.3 1.4 1 0 0 1 1 1 0 TMEM154 protein family Dicty_REP PF05086.12 EGO58629.1 - 7.6 4.4 7.1 9.9 4.0 7.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nucleoporin_FG PF13634.6 EGO58630.1 - 2.6e-18 66.6 142.7 3.1e-10 40.8 30.2 5.8 2 1 4 6 6 6 5 Nucleoporin FG repeat region TFIIA PF03153.13 EGO58630.1 - 0.00063 19.8 4.3 0.00063 19.8 4.3 2.6 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit Prominin PF05478.11 EGO58630.1 - 0.12 10.3 1.5 0.19 9.7 0.3 1.7 2 0 0 2 2 2 0 Prominin DASH_Dad2 PF08654.10 EGO58630.1 - 0.54 10.7 0.1 0.54 10.7 0.1 4.0 4 1 0 4 4 4 0 DASH complex subunit Dad2 RNA_pol_3_Rpc31 PF11705.8 EGO58631.1 - 7.7e-59 199.7 7.2 7.7e-59 199.7 7.2 2.2 1 1 1 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 DUF5060 PF16586.5 EGO58631.1 - 0.76 10.2 2.7 6.6 7.2 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5060) Sec7 PF01369.20 EGO58633.1 - 2.6e-70 235.8 2.2 3.9e-70 235.3 0.5 2.3 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 EGO58633.1 - 4.8e-41 140.3 1.7 4.8e-41 140.3 1.7 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EGO58633.1 - 1.5e-34 117.7 12.1 2.9e-33 113.6 0.2 6.0 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 EGO58633.1 - 1.8e-21 76.6 4.5 1.8e-19 70.1 0.5 3.4 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 VBS PF08913.10 EGO58633.1 - 0.036 14.5 0.2 0.14 12.6 0.1 2.0 2 0 0 2 2 2 0 Vinculin Binding Site 2-oxoacid_dh PF00198.23 EGO58634.1 - 1.5e-73 247.1 0.1 2e-73 246.7 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGO58634.1 - 3.1e-19 68.6 1.2 7e-19 67.4 1.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EGO58634.1 - 3.1e-15 56.2 0.8 8.9e-15 54.8 0.8 1.9 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 EGO58634.1 - 0.0048 17.4 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3614) Fungal_trans PF04082.18 EGO58635.1 - 5.2e-09 35.5 0.0 9.8e-09 34.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO58635.1 - 7.1e-07 29.2 12.6 1.2e-06 28.5 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 EGO58636.1 - 0.0069 16.0 6.6 0.0069 16.0 6.6 2.9 4 0 0 4 4 4 1 Spt20 family Myc_N PF01056.18 EGO58636.1 - 0.11 12.4 0.1 0.11 12.4 0.1 4.9 4 1 0 5 5 5 0 Myc amino-terminal region DUF4179 PF13786.6 EGO58637.1 - 0.11 12.9 0.0 0.15 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Glyco_hydro_7 PF00840.20 EGO58640.1 - 1.1e-166 554.9 4.7 1.3e-166 554.7 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 zf-C2HC5 PF06221.13 EGO58641.1 - 1.1e-21 76.5 7.5 1.7e-21 75.9 7.5 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF4407 PF14362.6 EGO58641.1 - 0.029 13.7 1.5 0.047 13.0 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomodulin PF03250.14 EGO58641.1 - 0.039 14.0 1.3 0.078 13.0 1.3 1.4 1 0 0 1 1 1 0 Tropomodulin FKBP_N PF01346.18 EGO58641.1 - 0.22 12.5 4.7 22 6.1 4.2 2.6 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Gln-synt_C PF00120.24 EGO58642.1 - 1.5e-17 63.7 0.0 2.1e-11 43.4 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EGO58642.1 - 4.8e-14 51.9 0.0 8.4e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain 2-Hacid_dh_C PF02826.19 EGO58643.1 - 1e-39 135.7 0.0 1.9e-24 86.0 0.0 2.9 2 1 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EGO58643.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1281_C PF18406.1 EGO58643.1 - 0.13 12.0 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein F420_oxidored PF03807.17 EGO58643.1 - 0.13 12.9 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 EGO58643.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain EphA2_TM PF14575.6 EGO58644.1 - 0.22 12.4 1.3 0.37 11.7 1.3 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SIR2 PF02146.17 EGO58645.1 - 3.5e-31 108.5 0.0 2.6e-09 37.3 0.0 3.3 3 0 0 3 3 3 3 Sir2 family PGM_PMM_I PF02878.16 EGO58646.1 - 0.092 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Fungal_trans PF04082.18 EGO58647.1 - 1.7e-20 73.2 3.2 2.7e-20 72.5 3.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO58647.1 - 7.1e-09 35.6 9.2 1.2e-08 34.9 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 EGO58648.1 - 4.1e-67 226.4 1.6 6.6e-67 225.7 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EGO58648.1 - 8.2e-60 202.5 0.1 1.4e-59 201.7 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EGO58648.1 - 2.1e-54 184.2 1.0 7.4e-54 182.4 0.1 2.5 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 EGO58648.1 - 2.3e-46 158.8 0.2 4.4e-46 157.9 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGO58648.1 - 1.1e-40 138.3 0.1 3.2e-40 136.8 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 EGO58648.1 - 4.8e-22 79.4 0.0 1.2e-19 71.7 0.0 3.4 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EGO58648.1 - 2.9e-20 72.8 0.0 8.2e-20 71.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EGO58648.1 - 7.2e-19 68.1 0.5 7.2e-19 68.1 0.5 4.3 5 0 0 5 5 4 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EGO58648.1 - 2.1e-15 57.1 2.5 3.2e-14 53.3 0.6 3.2 2 1 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EGO58648.1 - 2e-14 53.5 1.7 1e-11 44.7 0.0 2.8 2 0 0 2 2 2 2 short chain dehydrogenase Methyltransf_25 PF13649.6 EGO58648.1 - 6.3e-11 42.8 0.1 1.7e-09 38.2 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO58648.1 - 2.5e-10 40.8 0.0 2.7e-08 34.4 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO58648.1 - 4.3e-10 39.7 0.0 9.6e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EGO58648.1 - 3.4e-07 30.1 0.4 6.8e-06 25.8 0.0 2.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 EGO58648.1 - 2.5e-06 27.0 0.0 5.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGO58648.1 - 2.7e-06 27.2 0.0 6.5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EGO58648.1 - 1.4e-05 25.3 0.0 4.9e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Sacchrp_dh_NADP PF03435.18 EGO58648.1 - 0.00037 20.8 1.0 0.0018 18.6 0.1 2.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Thiolase_N PF00108.23 EGO58648.1 - 0.0028 17.0 1.5 0.0052 16.2 0.3 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain CoA_trans PF01144.23 EGO58648.1 - 0.006 16.0 0.0 1.5 8.2 0.0 2.5 2 0 0 2 2 2 1 Coenzyme A transferase Polysacc_synt_2 PF02719.15 EGO58648.1 - 0.011 14.8 0.2 0.029 13.5 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PALP PF00291.25 EGO58648.1 - 0.022 14.2 5.4 0.21 11.0 0.7 3.2 3 0 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme 3Beta_HSD PF01073.19 EGO58648.1 - 0.034 13.2 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_8 PF05148.15 EGO58648.1 - 0.036 13.9 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Epimerase PF01370.21 EGO58648.1 - 0.037 13.5 0.1 0.074 12.5 0.1 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NdhM PF10664.9 EGO58648.1 - 0.062 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M TrkA_N PF02254.18 EGO58648.1 - 0.17 12.1 0.1 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.20 EGO58648.1 - 0.18 11.8 0.0 0.48 10.5 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 EGO58650.1 - 5.5e-07 29.2 0.0 2.2e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EGO58650.1 - 0.0002 21.3 0.0 0.00077 19.4 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 EGO58650.1 - 0.028 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Ank_2 PF12796.7 EGO58651.1 - 1.9e-34 118.1 0.5 7.5e-08 32.9 0.0 7.3 5 2 2 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO58651.1 - 1.3e-27 95.7 5.2 0.00019 21.9 0.0 9.1 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO58651.1 - 9.3e-25 84.0 18.2 0.043 14.4 0.0 12.2 12 1 0 12 12 12 6 Ankyrin repeat Ank PF00023.30 EGO58651.1 - 8.3e-20 70.3 18.3 0.051 14.0 0.1 10.2 11 1 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 EGO58651.1 - 7e-13 48.5 18.7 0.11 12.8 0.0 8.4 8 2 1 9 9 9 6 Ankyrin repeats (many copies) F-box-like PF12937.7 EGO58651.1 - 4.7e-06 26.4 0.2 1.8e-05 24.6 0.1 2.1 2 0 0 2 2 2 1 F-box-like CDV3 PF15359.6 EGO58652.1 - 0.0056 17.2 3.3 0.0061 17.0 3.3 1.1 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 Alpha_GJ PF03229.13 EGO58652.1 - 0.31 11.6 5.4 0.51 10.9 5.3 1.4 1 1 0 1 1 1 0 Alphavirus glycoprotein J DUF4551 PF15087.6 EGO58652.1 - 0.49 9.2 2.2 0.47 9.2 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Nrf1_activ_bdg PF10492.9 EGO58652.1 - 2.5 8.8 7.9 1.2 9.9 3.4 2.1 1 1 1 2 2 2 0 Nrf1 activator activation site binding domain Esterase_phd PF10503.9 EGO58653.1 - 1.5e-23 83.5 1.0 2.1e-23 83.0 1.0 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EGO58653.1 - 2.7e-07 30.3 1.3 3.7e-07 29.9 1.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EGO58653.1 - 0.0016 18.1 0.6 0.0028 17.4 0.6 1.3 1 0 0 1 1 1 1 Putative esterase COesterase PF00135.28 EGO58653.1 - 0.012 14.6 1.5 0.023 13.6 0.3 1.8 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_2 PF02230.16 EGO58653.1 - 0.15 11.8 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AOX PF01786.17 EGO58656.1 - 2.1e-87 292.2 0.0 2.5e-87 292.0 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase BTB PF00651.31 EGO58659.1 - 0.0046 17.2 0.0 0.0083 16.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain RRM_1 PF00076.22 EGO58660.1 - 0.00061 19.6 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2076 PF09849.9 EGO58662.1 - 2 8.4 8.1 2.1 8.3 8.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TerB_N PF13208.6 EGO58665.1 - 0.013 15.3 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 TerB N-terminal domain Golgin_A5 PF09787.9 EGO58666.1 - 0.063 12.7 53.9 0.16 11.4 14.6 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 Ank_2 PF12796.7 EGO58667.1 - 1.1e-14 54.8 0.1 6.7e-09 36.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO58667.1 - 3.3e-12 45.4 1.2 0.012 16.1 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EGO58667.1 - 4.1e-12 46.1 1.5 2.1e-06 27.9 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGO58667.1 - 3.3e-10 40.3 0.7 2.3e-08 34.4 0.0 2.7 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EGO58667.1 - 1.8e-09 37.6 1.3 0.15 12.5 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Glyco_hydro_18 PF00704.28 EGO58669.1 - 9.2e-92 308.1 8.2 1.1e-91 307.9 8.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Abhydrolase_3 PF07859.13 EGO58670.1 - 1.5e-28 100.1 0.0 2.4e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO58670.1 - 1.2e-07 32.6 0.4 1.7e-07 32.1 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 EGO58670.1 - 3.1e-05 22.8 0.0 4.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) COesterase PF00135.28 EGO58670.1 - 6.1e-05 22.1 0.0 0.032 13.1 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.21 EGO58670.1 - 0.0008 18.9 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EGO58670.1 - 0.054 13.1 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EGO58670.1 - 0.057 13.1 0.0 0.22 11.2 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold T2SSI PF02501.17 EGO58670.1 - 0.081 13.1 1.4 0.13 12.4 0.4 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein I Glyco_hydro_31 PF01055.26 EGO58671.1 - 1.2e-94 318.0 6.3 1.8e-94 317.4 6.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 EGO58671.1 - 3e-05 24.2 0.0 7.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) DUF5512 PF17631.2 EGO58671.1 - 0.019 15.0 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5512) MFS_1 PF07690.16 EGO58672.1 - 1.3e-49 169.1 22.8 1.3e-49 169.1 22.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO58672.1 - 3.1e-13 49.4 14.6 4.8e-13 48.8 1.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EGO58672.1 - 6e-11 41.5 2.6 9.4e-11 40.8 2.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EGO58672.1 - 6.3e-05 21.5 6.8 0.00057 18.3 1.6 2.8 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EGO58672.1 - 0.0005 18.6 2.4 0.00093 17.7 2.4 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector Ctr PF04145.15 EGO58672.1 - 0.23 12.1 4.6 0.43 11.2 1.1 2.8 2 1 0 2 2 2 0 Ctr copper transporter family Peptidase_M20 PF01546.28 EGO58673.1 - 5e-33 114.5 0.0 1.6e-32 112.9 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGO58673.1 - 7.3e-13 48.4 0.2 2.3e-12 46.8 0.2 1.9 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGO58673.1 - 0.00027 20.7 0.0 0.00064 19.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 DUF755 PF05501.11 EGO58673.1 - 0.059 13.6 11.0 0.043 14.1 4.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) IMUP PF15761.5 EGO58673.1 - 2.1 9.1 9.9 4.7 7.9 2.4 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein Mannosyl_trans3 PF11051.8 EGO58674.1 - 6.5e-46 156.9 0.0 4.3e-29 101.7 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative TMEM206 PF15122.6 EGO58676.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 TMEM206 protein family DUF908 PF06012.12 EGO58681.1 - 1.2 8.5 5.2 1.9 7.8 5.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) E1-E2_ATPase PF00122.20 EGO58683.1 - 7.5e-17 61.4 0.0 1.7e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EGO58683.1 - 1.4e-14 54.9 3.4 1.1e-08 35.7 3.2 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGO58683.1 - 0.00024 21.1 0.0 0.0056 16.7 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGO58683.1 - 0.003 17.3 0.1 0.055 13.2 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EGO58683.1 - 0.0035 16.9 0.2 1.6 8.2 0.0 3.1 3 0 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase TRAP-gamma PF07074.12 EGO58683.1 - 0.032 13.8 4.0 0.08 12.5 4.0 1.6 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF4059 PF13268.6 EGO58683.1 - 0.83 10.1 3.2 13 6.3 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) Ldh_1_C PF02866.18 EGO58684.1 - 1.2e-47 161.9 0.0 2e-47 161.2 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EGO58684.1 - 2.8e-45 153.9 0.0 4.7e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EGO58684.1 - 0.00014 21.0 0.0 0.00021 20.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EGO58684.1 - 0.15 12.5 0.5 0.57 10.6 0.0 2.2 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Spt20 PF12090.8 EGO58685.1 - 0.99 9.0 33.0 0.49 10.0 5.0 2.4 2 0 0 2 2 2 0 Spt20 family BSMAP PF12280.8 EGO58686.1 - 0.013 15.8 0.3 0.015 15.5 0.3 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein Na_H_Exchanger PF00999.21 EGO58687.1 - 1e-37 129.9 32.1 1.4e-37 129.4 32.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pro-kuma_activ PF09286.11 EGO58688.1 - 1.3e-30 106.6 0.2 2e-30 106.0 0.2 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGO58688.1 - 3.7e-07 29.7 0.0 6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Methyltransf_23 PF13489.6 EGO58690.1 - 6.6e-12 45.6 0.0 9.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO58690.1 - 2.4e-07 31.3 0.0 4.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO58690.1 - 4.6e-07 30.5 0.0 1.3e-06 29.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO58690.1 - 0.00049 20.8 0.0 0.0018 19.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO58690.1 - 0.015 15.1 0.0 0.066 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 EGO58690.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGO58691.1 - 4.5e-19 68.9 0.0 6.7e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO58691.1 - 6.1e-14 52.5 0.0 1.6e-13 51.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO58691.1 - 2.8e-11 43.9 0.0 6.8e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO58691.1 - 3.9e-08 33.9 0.0 1.1e-07 32.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO58691.1 - 5.5e-07 29.5 0.0 5.1e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO58691.1 - 0.00045 19.6 0.0 0.0041 16.5 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGO58691.1 - 0.0024 17.5 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EGO58691.1 - 0.006 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.9 EGO58691.1 - 0.0064 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase DUF938 PF06080.12 EGO58691.1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 EGO58691.1 - 0.032 13.5 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 EGO58691.1 - 0.039 13.3 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EGO58691.1 - 0.096 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 EGO58692.1 - 3e-16 59.7 0.0 4.6e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO58692.1 - 1.9e-10 41.3 0.0 4.4e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO58692.1 - 3.4e-08 34.0 0.0 5.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO58692.1 - 2.4e-05 25.0 0.0 0.0001 23.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO58692.1 - 5.1e-05 23.1 0.0 0.00086 19.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO58692.1 - 0.00086 18.9 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGO58692.1 - 0.0018 17.7 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 EGO58692.1 - 0.0092 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.9 EGO58692.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 EGO58692.1 - 0.024 14.4 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 EGO58692.1 - 0.18 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EGO58692.1 - 0.21 10.9 0.0 2 7.7 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CG-1 PF03859.16 EGO58693.1 - 0.066 13.0 1.0 0.076 12.8 1.0 1.0 1 0 0 1 1 1 0 CG-1 domain MMR1 PF08505.10 EGO58693.1 - 0.087 13.1 0.1 0.1 12.9 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Methyltransf_23 PF13489.6 EGO58694.1 - 1e-13 51.5 0.0 1.5e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO58694.1 - 6.2e-11 42.9 0.0 2e-10 41.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO58694.1 - 1.1e-09 38.8 0.0 2.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO58694.1 - 4e-06 26.7 0.0 8.9e-05 22.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO58694.1 - 8.6e-05 23.2 0.0 0.00049 20.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO58694.1 - 0.00032 20.1 0.0 0.003 16.9 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGO58694.1 - 0.0019 17.8 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 EGO58694.1 - 0.023 14.5 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PG_binding_1 PF01471.18 EGO58695.1 - 0.098 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative peptidoglycan binding domain TSP_NTD PF17804.1 EGO58697.1 - 0.017 15.4 1.2 0.035 14.4 1.2 1.4 1 0 0 1 1 1 0 Tail specific protease N-terminal domain RNA_pol_Rpo13 PF12136.8 EGO58699.1 - 0.023 14.6 0.0 0.084 12.8 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain Phage_Coat_A PF05357.13 EGO58700.1 - 0.00042 20.0 0.0 0.00074 19.3 0.0 1.4 1 0 0 1 1 1 1 Phage Coat Protein A 17kDa_Anti_2 PF16998.5 EGO58700.1 - 0.048 13.6 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 17 kDa outer membrane surface antigen HET PF06985.11 EGO58701.1 - 1e-13 51.9 7.9 3e-11 43.8 1.8 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Methyltransf_23 PF13489.6 EGO58703.1 - 8.3e-19 68.0 0.0 1.5e-18 67.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO58703.1 - 7.5e-13 49.0 0.0 2.2e-12 47.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO58703.1 - 1.8e-11 44.5 0.0 4.3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO58703.1 - 1.8e-08 35.0 0.0 1.1e-07 32.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO58703.1 - 2.2e-07 30.8 0.0 6e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO58703.1 - 3.2e-05 23.5 0.0 6.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EGO58703.1 - 0.00024 20.5 0.0 0.0026 17.1 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EGO58703.1 - 0.0035 17.1 0.0 0.0064 16.2 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 EGO58703.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 EGO58703.1 - 0.016 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EGO58703.1 - 0.016 14.5 0.0 0.036 13.4 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain FtsJ PF01728.19 EGO58703.1 - 0.022 14.8 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Abi_C PF14355.6 EGO58703.1 - 0.035 14.2 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Abortive infection C-terminus DUF938 PF06080.12 EGO58703.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_23 PF13489.6 EGO58704.1 - 3.4e-18 66.0 0.0 5e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO58704.1 - 1.8e-11 44.6 0.0 6.4e-11 42.8 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO58704.1 - 2.8e-08 34.3 0.0 6.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO58704.1 - 1.7e-06 27.9 0.0 3.8e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO58704.1 - 2.6e-06 28.1 0.0 1e-05 26.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO58704.1 - 0.00011 21.8 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EGO58704.1 - 0.0028 17.0 0.1 0.044 13.1 0.0 2.3 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EGO58704.1 - 0.0098 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase DUF938 PF06080.12 EGO58704.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.13 EGO58704.1 - 0.032 13.6 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EGO58704.1 - 0.053 13.6 0.0 0.14 12.3 0.0 1.6 1 1 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EGO58704.1 - 0.068 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Lactamase_B_3 PF13483.6 EGO58705.1 - 3.9e-14 52.9 0.5 2.4e-13 50.3 0.5 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EGO58705.1 - 2.1e-13 50.3 0.0 1e-12 48.0 0.0 2.0 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGO58705.1 - 0.0015 18.5 2.7 0.0075 16.3 0.5 2.7 2 1 1 3 3 3 1 Metallo-beta-lactamase superfamily DUF5423 PF17461.2 EGO58706.1 - 2.4 6.9 9.5 3.1 6.5 9.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Neuralized PF07177.12 EGO58707.1 - 0.072 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Neuralized DUF3782 PF12644.7 EGO58707.1 - 0.14 12.3 0.3 0.54 10.5 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3782) Methyltransf_23 PF13489.6 EGO58709.1 - 7.4e-15 55.2 0.0 2.9e-14 53.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO58709.1 - 4.5e-11 43.3 0.0 1.2e-10 42.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO58709.1 - 1.1e-08 35.6 0.0 2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO58709.1 - 1.8e-05 25.4 0.0 8.9e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO58709.1 - 3.3e-05 23.4 0.0 0.00058 19.3 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGO58709.1 - 0.00034 20.4 0.0 0.0086 15.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO58709.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EGO58709.1 - 0.024 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 EGO58709.1 - 0.039 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 EGO58709.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 EGO58709.1 - 0.23 11.5 0.0 0.43 10.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF1295 PF06966.12 EGO58713.1 - 1.1e-32 113.4 0.0 1.7e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EGO58713.1 - 9.1e-05 22.5 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EGO58713.1 - 0.0004 20.7 0.0 0.00094 19.5 0.0 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 EGO58713.1 - 0.0019 18.6 0.0 0.0043 17.4 0.0 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 EGO58713.1 - 0.0058 15.4 0.0 0.0089 14.8 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Hydrolase_6 PF13344.6 EGO58716.1 - 8.6e-22 77.2 0.0 1.8e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO58716.1 - 1.1e-18 67.1 0.0 3.2e-18 65.6 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EGO58716.1 - 0.089 13.1 0.0 4.7 7.4 0.0 2.4 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGO58716.1 - 0.097 12.7 0.1 0.77 9.8 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.21 EGO58717.1 - 3.1e-54 184.2 0.0 8.3e-54 182.8 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Sugarporin_N PF11471.8 EGO58720.1 - 0.00042 20.2 0.2 0.027 14.4 0.0 3.3 4 0 0 4 4 4 1 Maltoporin periplasmic N-terminal extension Whi5 PF08528.11 EGO58721.1 - 5.4e-12 45.1 0.0 9e-12 44.4 0.0 1.4 1 0 0 1 1 1 1 Whi5 like DUF3328 PF11807.8 EGO58723.1 - 3.4e-41 141.4 0.6 4.4e-41 141.1 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SCIMP PF15050.6 EGO58723.1 - 0.031 14.8 0.1 0.06 13.8 0.1 1.5 1 0 0 1 1 1 0 SCIMP protein MlrC_C PF07171.12 EGO58724.1 - 0.089 13.0 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 MlrC C-terminus COesterase PF00135.28 EGO58725.1 - 5.3e-84 282.9 0.0 7.3e-84 282.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO58725.1 - 1.6e-08 34.7 0.1 6.5e-08 32.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO58725.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family SLATT_1 PF18181.1 EGO58726.1 - 0.15 12.0 1.1 15 5.5 0.0 2.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Wzy_C PF04932.15 EGO58726.1 - 5.2 6.7 20.2 2.2 7.9 0.8 3.2 3 0 0 3 3 3 0 O-Antigen ligase NAD_binding_10 PF13460.6 EGO58728.1 - 0.003 17.5 0.0 0.0052 16.7 0.0 1.3 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EGO58728.1 - 0.023 14.1 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGO58728.1 - 0.027 13.7 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Sacchrp_dh_NADP PF03435.18 EGO58728.1 - 0.03 14.6 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 EGO58728.1 - 0.049 13.8 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 EGO58728.1 - 0.058 12.5 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 EGO58728.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 2 0 0 2 2 2 0 KR domain NYD-SP12_N PF15015.6 EGO58729.1 - 0.0096 14.3 0.3 0.014 13.7 0.3 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal uDENN PF03456.18 EGO58729.1 - 0.039 14.7 0.4 0.11 13.3 0.4 1.7 1 0 0 1 1 1 0 uDENN domain Dynamin_N PF00350.23 EGO58731.1 - 1.6e-41 142.2 0.1 3.1e-41 141.2 0.1 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EGO58731.1 - 3.4e-24 85.6 0.3 8.2e-24 84.3 0.3 1.7 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EGO58731.1 - 1.7e-05 24.8 0.0 0.00016 21.7 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase LPD3 PF18798.1 EGO58731.1 - 0.0078 16.5 0.1 0.092 13.0 0.0 2.6 2 0 0 2 2 2 1 Large polyvalent protein-associated domain 3 M16C_assoc PF08367.11 EGO58731.1 - 0.015 14.4 0.0 0.038 13.1 0.0 1.6 1 0 0 1 1 1 0 Peptidase M16C associated FeoB_N PF02421.18 EGO58731.1 - 0.043 13.4 0.1 3.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_15 PF13175.6 EGO58731.1 - 0.045 13.5 0.9 0.17 11.6 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.6 EGO58731.1 - 0.073 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGO58731.1 - 0.091 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain UDPG_MGDP_dh_N PF03721.14 EGO58732.1 - 2e-48 164.4 0.0 1.9e-30 105.9 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EGO58732.1 - 3.8e-31 107.1 0.0 7.6e-31 106.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EGO58732.1 - 2.6e-23 82.5 0.0 9.1e-19 67.8 0.0 3.3 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 EGO58732.1 - 0.00051 20.3 0.0 0.016 15.4 0.0 2.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 EGO58732.1 - 0.11 12.6 0.0 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 EGO58732.1 - 0.12 12.3 0.0 5.9 6.9 0.0 2.8 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GMC_oxred_C PF05199.13 EGO58733.1 - 2.2e-32 112.5 0.0 3.6e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EGO58733.1 - 9.3e-27 94.2 0.0 2.6e-16 59.9 0.1 3.2 3 0 0 3 3 3 3 GMC oxidoreductase Pyr_redox_2 PF07992.14 EGO58733.1 - 0.0014 17.9 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO58733.1 - 0.0017 18.5 0.4 0.0052 17.0 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGO58733.1 - 0.016 14.3 0.7 0.025 13.7 0.7 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EGO58733.1 - 0.16 11.0 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 EGO58733.1 - 0.17 11.5 0.1 0.39 10.4 0.1 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 EGO58733.1 - 0.17 10.5 0.3 0.24 10.0 0.3 1.1 1 0 0 1 1 1 0 HI0933-like protein DUF5134 PF17197.4 EGO58734.1 - 0.23 11.4 3.2 0.45 10.4 3.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) ADH_zinc_N_2 PF13602.6 EGO58735.1 - 2.7e-25 90.0 0.0 3.8e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGO58735.1 - 1.6e-15 57.3 0.1 2.5e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO58735.1 - 1.3e-05 25.0 0.1 6.5e-05 22.8 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain IBR PF01485.21 EGO58736.1 - 5.4e-05 23.3 8.0 5.4e-05 23.3 8.0 2.2 3 0 0 3 3 3 1 IBR domain, a half RING-finger domain AA_permease_2 PF13520.6 EGO58738.1 - 2.6e-73 247.3 26.6 3.1e-73 247.0 26.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO58738.1 - 6.5e-09 34.9 26.2 4.1e-08 32.2 26.2 2.3 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 EGO58738.1 - 0.37 9.4 18.9 0.11 11.1 12.4 2.7 2 1 0 2 2 2 0 Transmembrane amino acid transporter protein V-SNARE_C PF12352.8 EGO58740.1 - 1.4e-13 50.9 0.8 1.4e-13 50.9 0.8 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EGO58740.1 - 4.7e-05 23.2 0.1 0.00041 20.2 0.0 2.3 2 1 1 3 3 3 1 Sec20 Sigma70_r4 PF04545.16 EGO58740.1 - 0.01 15.3 0.1 0.024 14.1 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 FliD_N PF02465.18 EGO58740.1 - 0.022 15.4 1.2 0.15 12.8 0.1 2.7 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF3175 PF11373.8 EGO58740.1 - 0.03 14.5 0.8 0.23 11.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3175) KxDL PF10241.9 EGO58740.1 - 0.057 13.7 6.1 0.42 10.9 1.5 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein TPR_MLP1_2 PF07926.12 EGO58740.1 - 0.077 13.1 5.3 3.5 7.7 2.0 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 EGO58740.1 - 0.19 11.1 2.8 0.51 9.6 2.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PilJ PF13675.6 EGO58740.1 - 0.38 10.8 5.7 0.72 9.9 0.3 3.0 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term CHCH PF06747.13 EGO58741.1 - 2.9e-07 30.4 4.6 4.7e-07 29.8 4.6 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EGO58741.1 - 0.035 14.5 2.8 0.09 13.2 2.8 1.7 1 0 0 1 1 1 0 GCK domain DUF5353 PF17304.2 EGO58742.1 - 6.6e-12 45.0 4.8 1.6e-11 43.8 4.6 1.7 1 1 1 2 2 2 1 Family of unknown function (DUF5353) YlqD PF11068.8 EGO58742.1 - 0.023 15.1 4.4 0.032 14.6 4.4 1.1 1 0 0 1 1 1 0 YlqD protein ApoO PF09769.9 EGO58742.1 - 0.025 14.5 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein O DUF1168 PF06658.12 EGO58742.1 - 0.15 11.8 10.2 0.22 11.3 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) G0-G1_switch_2 PF15103.6 EGO58742.1 - 0.32 11.5 3.5 0.53 10.7 3.5 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 RR_TM4-6 PF06459.12 EGO58742.1 - 0.37 10.6 6.8 0.48 10.2 6.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1682 PF07946.14 EGO58742.1 - 1.1 8.4 8.0 1.4 8.0 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RNA_pol_Rpc4 PF05132.14 EGO58742.1 - 1.2 9.5 9.1 1.7 9.1 9.1 1.3 1 1 0 1 1 1 0 RNA polymerase III RPC4 ATP-synt_B PF00430.18 EGO58742.1 - 2.6 8.1 17.9 4.8 7.3 17.9 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) zf-P11 PF03854.14 EGO58745.1 - 0.17 11.5 0.2 0.17 11.5 0.2 2.4 3 0 0 3 3 3 0 P-11 zinc finger DZR PF12773.7 EGO58745.1 - 0.86 9.7 11.6 7.3e+02 0.3 11.6 2.8 1 1 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.11 EGO58745.1 - 1.7 8.4 9.0 11 5.8 0.1 3.2 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain tRNA-synt_1g PF09334.11 EGO58745.1 - 2.2 6.9 3.7 2.4 6.8 3.7 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) Nsp2a_N PF17896.1 EGO58746.1 - 0.11 11.7 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 Replicase polyprotein 1a N-terminal domain Glyco_hydro_3_C PF01915.22 EGO58747.1 - 3.1e-53 180.8 0.0 6.7e-53 179.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO58747.1 - 1.2e-44 153.0 0.0 2.1e-44 152.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGO58747.1 - 1.6e-25 89.0 0.0 3.3e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Diphtheria_C PF02763.14 EGO58747.1 - 0.096 12.3 0.2 0.19 11.4 0.2 1.4 1 0 0 1 1 1 0 Diphtheria toxin, C domain Ser_hydrolase PF06821.13 EGO58747.1 - 0.096 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Asp PF00026.23 EGO58748.1 - 1.1e-65 222.1 2.9 1.4e-65 221.8 2.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO58748.1 - 9.1e-08 32.5 1.5 0.0015 18.8 0.5 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO58748.1 - 1.1e-05 25.9 7.0 0.0032 18.1 0.6 3.4 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EGO58748.1 - 0.0071 16.9 8.1 0.84 10.2 0.7 3.6 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease Myb_DNA-bind_3 PF12776.7 EGO58749.1 - 2.1e-25 89.5 0.6 4.3e-25 88.5 0.6 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MAP65_ASE1 PF03999.12 EGO58749.1 - 8 5.0 6.5 10 4.6 6.5 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) zinc-ribbons_6 PF07191.12 EGO58750.1 - 3.2 7.8 13.5 11 6.1 0.5 2.8 2 1 0 2 2 2 0 zinc-ribbons Glyco_hydro_16 PF00722.21 EGO58752.1 - 1.7e-14 53.7 0.1 2.6e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EGO58752.1 - 0.00044 18.8 0.7 0.38 9.1 0.6 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Zn_clus PF00172.18 EGO58753.1 - 8.2e-07 29.0 30.6 5.3e-05 23.3 9.0 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.8 EGO58753.1 - 0.014 15.3 5.6 0.03 14.3 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 EGO58753.1 - 0.15 10.3 9.9 0.24 9.5 9.9 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sugar_tr PF00083.24 EGO58757.1 - 4.8e-126 421.2 23.0 5.6e-126 421.0 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO58757.1 - 2.1e-22 79.6 53.0 3.5e-20 72.2 29.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Thioredoxin_13 PF18401.1 EGO58757.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain HEPN_SAV2148 PF18725.1 EGO58759.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 SAV2148-like HEPN Flg_new PF09479.10 EGO58760.1 - 0.02 15.1 0.0 0.039 14.2 0.0 1.5 2 0 0 2 2 2 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) DUF3248 PF11609.8 EGO58761.1 - 0.17 11.8 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) Pentapeptide_2 PF01469.18 EGO58766.1 - 0.00045 20.0 0.6 0.0017 18.2 0.6 1.8 2 0 0 2 2 2 1 Pentapeptide repeats (8 copies) FA_hydroxylase PF04116.13 EGO58770.1 - 2.8e-25 89.2 24.5 1.9e-24 86.5 22.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4727 PF15856.5 EGO58770.1 - 0.074 12.6 1.1 0.11 12.1 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4727) ANAPC4_WD40 PF12894.7 EGO58774.1 - 0.0047 17.2 0.1 0.23 11.8 0.0 2.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGO58774.1 - 0.098 13.6 5.7 12 6.9 0.2 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat HlyIII PF03006.20 EGO58775.1 - 1.6e-68 230.8 18.8 1.9e-68 230.5 18.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related YfhO PF09586.10 EGO58775.1 - 1.1 7.5 10.4 0.13 10.5 0.8 2.1 2 0 0 2 2 2 0 Bacterial membrane protein YfhO TssN PF17555.2 EGO58775.1 - 5.5 6.3 14.6 0.52 9.6 4.0 2.2 1 1 1 2 2 2 0 Type VI secretion system, TssN Ndc1_Nup PF09531.10 EGO58775.1 - 9.3 4.8 8.7 16 4.1 8.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Prefoldin PF02996.17 EGO58776.1 - 0.002 18.1 0.3 0.12 12.2 0.0 2.2 1 1 1 2 2 2 1 Prefoldin subunit Fib_alpha PF08702.10 EGO58776.1 - 0.03 14.5 4.0 3.7 7.7 0.3 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 EGO58776.1 - 0.052 13.4 1.3 3.2 7.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) HSCB_C PF07743.13 EGO58776.1 - 0.061 13.8 5.0 1.5 9.4 0.4 2.2 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF4472 PF14739.6 EGO58776.1 - 0.23 12.2 3.5 7.9 7.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) DUF4600 PF15372.6 EGO58776.1 - 0.62 10.5 3.5 10 6.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) SYCE1 PF15233.6 EGO58776.1 - 3.9 7.5 6.8 3.5 7.7 0.8 2.1 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 NPV_P10 PF05531.12 EGO58776.1 - 10 6.7 9.6 13 6.3 1.5 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.25 EGO58778.1 - 1.2e-55 188.8 0.0 1.6e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO58778.1 - 1.4e-33 116.3 0.0 1.9e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO58778.1 - 5.8e-05 22.5 0.0 8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGO58778.1 - 0.0046 16.3 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EGO58778.1 - 0.055 12.4 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 EGO58778.1 - 0.074 13.0 0.0 0.2 11.5 0.0 1.5 1 1 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGO58778.1 - 0.098 11.6 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EGO58778.1 - 0.17 11.5 0.0 0.74 9.4 0.0 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 EGO58779.1 - 2.2e-53 181.3 0.0 2.9e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO58779.1 - 4.4e-24 85.2 0.0 1.1e-23 83.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EGO58779.1 - 0.086 11.8 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EGO58779.1 - 0.093 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family TMA7 PF09072.10 EGO58780.1 - 2.4e-25 89.1 21.6 2.6e-25 89.0 21.6 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 RSN1_7TM PF02714.15 EGO58781.1 - 3.9e-84 282.2 18.4 9e-84 281.0 18.4 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EGO58781.1 - 2.5e-40 138.6 0.0 3.6e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EGO58781.1 - 5.2e-39 133.5 4.8 5.2e-39 133.5 4.8 2.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF1192 PF06698.11 EGO58781.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) FAD_binding_4 PF01565.23 EGO58782.1 - 2.9e-30 104.8 0.7 4.6e-30 104.2 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGO58782.1 - 1e-14 54.3 0.5 2.7e-14 53.0 0.5 1.8 1 0 0 1 1 1 1 Berberine and berberine like Exonuc_X-T_C PF08411.10 EGO58782.1 - 0.019 14.1 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Exonuclease C-terminal E1-E2_ATPase PF00122.20 EGO58784.1 - 6.5e-38 130.1 19.3 2.3e-30 105.5 0.5 3.9 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGO58784.1 - 9.2e-32 110.2 1.2 9.2e-32 110.2 1.2 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGO58784.1 - 1.5e-20 73.1 0.0 3.5e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGO58784.1 - 1.5e-18 67.8 0.7 1.5e-14 54.8 0.1 3.2 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGO58784.1 - 1.6e-15 56.5 0.0 4.4e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGO58784.1 - 1.1e-06 28.6 0.9 1.1e-05 25.3 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1206 PF06724.11 EGO58784.1 - 0.0022 18.0 0.7 6.8 6.9 0.0 3.9 3 0 0 3 3 3 2 Domain of Unknown Function (DUF1206) Glycos_transf_2 PF00535.26 EGO58785.1 - 1.5e-34 119.2 0.0 1.8e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGO58785.1 - 1.7e-13 51.0 0.0 2.4e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGO58785.1 - 2.9e-05 23.6 0.0 4.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 EGO58785.1 - 6.6e-05 22.5 0.0 9.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EGO58785.1 - 0.07 13.7 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 MSA-2c PF12238.8 EGO58786.1 - 0.002 18.1 1.7 0.003 17.6 1.7 1.2 1 0 0 1 1 1 1 Merozoite surface antigen 2c CSN8_PSD8_EIF3K PF10075.9 EGO58786.1 - 0.13 12.3 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family CFEM PF05730.11 EGO58787.1 - 6.6e-12 45.3 9.4 6.6e-12 45.3 9.4 1.8 2 1 0 2 2 2 1 CFEM domain TraW_N PF12477.8 EGO58787.1 - 0.049 13.6 1.2 0.049 13.6 1.2 3.8 3 0 0 3 3 3 0 Sex factor F TraW protein N terminal FAM199X PF15814.5 EGO58787.1 - 2.1 7.3 8.7 3.1 6.8 8.7 1.2 1 0 0 1 1 1 0 Protein family FAM199X MFS_1 PF07690.16 EGO58788.1 - 3.9e-33 114.8 19.6 3.9e-33 114.8 19.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO58788.1 - 1.3e-13 50.6 0.0 1.3e-13 50.6 0.0 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter Rick_17kDa_Anti PF05433.15 EGO58788.1 - 0.66 9.9 7.1 2.8 7.9 0.5 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EGO58788.1 - 0.69 10.0 9.3 0.67 10.0 2.8 2.6 2 0 0 2 2 2 0 Glycine zipper His_Phos_2 PF00328.22 EGO58789.1 - 9.2e-09 35.1 0.0 2.3e-07 30.5 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) adh_short_C2 PF13561.6 EGO58790.1 - 2.4e-36 125.5 1.7 3.6e-36 124.9 1.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO58790.1 - 3.2e-32 111.6 1.2 4.7e-32 111.0 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO58790.1 - 4e-09 36.6 0.8 8.5e-08 32.3 0.1 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EGO58790.1 - 0.0055 16.2 0.2 0.19 11.2 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Rad60-SLD PF11976.8 EGO58791.1 - 1.6e-22 79.1 1.0 8e-20 70.5 1.3 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like KH_8 PF17903.1 EGO58792.1 - 0.0033 17.5 0.0 0.0069 16.5 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EGO58792.1 - 0.039 13.8 0.4 0.096 12.5 0.4 1.7 1 0 0 1 1 1 0 KH domain MDM31_MDM32 PF08118.11 EGO58793.1 - 2.8e-252 838.1 0.0 3.7e-252 837.7 0.0 1.2 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins TraH_2 PF06871.11 EGO58793.1 - 0.01 15.5 0.3 0.022 14.4 0.3 1.5 1 0 0 1 1 1 0 TraH_2 Pex14_N PF04695.13 EGO58793.1 - 0.05 14.3 0.1 0.05 14.3 0.1 2.4 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF3_subunit PF08597.10 EGO58794.1 - 2e-73 247.3 25.3 2.2e-73 247.2 25.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Nop53 PF07767.11 EGO58794.1 - 0.095 12.1 32.0 0.51 9.7 0.2 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Rrn6 PF10214.9 EGO58794.1 - 0.12 10.8 7.8 0.2 10.1 7.8 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor FAM60A PF15396.6 EGO58794.1 - 2.1 8.3 10.3 0.28 11.1 4.8 1.9 2 0 0 2 2 2 0 Protein Family FAM60A Vpu PF00558.19 EGO58794.1 - 2.1 8.1 6.1 7.3 6.4 6.1 1.9 1 0 0 1 1 1 0 Vpu protein IHABP4_N PF16174.5 EGO58794.1 - 6.9 7.3 23.2 1.2 9.7 14.2 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal AOX PF01786.17 EGO58795.1 - 5.3e-92 307.2 0.3 6.5e-92 307.0 0.3 1.1 1 0 0 1 1 1 1 Alternative oxidase zf-H2C2_2 PF13465.6 EGO58796.1 - 2.3e-11 43.6 15.1 3.3e-08 33.6 0.7 4.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 EGO58796.1 - 2.6e-11 43.3 18.5 1.4e-06 28.4 2.4 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGO58796.1 - 9.9e-09 35.0 6.7 5.1e-05 23.1 0.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EGO58796.1 - 2.2e-06 28.0 18.5 0.00045 20.8 1.7 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 EGO58796.1 - 2.4e-06 27.7 1.8 0.0048 17.2 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGO58796.1 - 0.00037 20.7 13.4 0.076 13.3 0.2 4.0 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EGO58796.1 - 0.099 12.4 3.8 4.7 7.1 0.4 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HE PF16278.5 EGO58796.1 - 1 9.9 3.0 24 5.4 0.3 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 EGO58796.1 - 1.4 9.2 4.6 6.4 7.1 0.1 2.3 1 1 1 2 2 2 0 LIM domain TNT PF14021.6 EGO58798.1 - 7.5e-36 122.6 0.4 9.8e-35 119.0 0.0 2.3 2 0 0 2 2 2 1 Tuberculosis necrotizing toxin GLTP PF08718.11 EGO58799.1 - 4e-47 160.2 0.1 7.9e-47 159.3 0.0 1.5 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) PLDc_2 PF13091.6 EGO58800.1 - 7.3e-17 61.5 0.4 4.9e-06 26.5 0.1 3.6 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 EGO58800.1 - 6.7e-15 54.6 1.2 2.8e-07 30.4 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Fungal_trans PF04082.18 EGO58802.1 - 4.2e-21 75.2 0.2 6.7e-21 74.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO58802.1 - 0.021 15.0 2.4 0.057 13.5 2.4 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DeoC PF01791.9 EGO58803.1 - 3.3e-12 46.5 0.9 4.5e-12 46.1 0.9 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase Glu_synthase PF01645.17 EGO58803.1 - 0.026 13.7 0.1 0.041 13.0 0.1 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase NanE PF04131.14 EGO58803.1 - 0.061 12.5 0.1 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF1805 PF08827.11 EGO58803.1 - 0.42 11.0 2.4 2.7 8.4 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1805) DUF218 PF02698.17 EGO58804.1 - 3.5e-08 33.5 0.0 5.8e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 DUF218 domain Nop52 PF05997.12 EGO58805.1 - 9.8e-57 192.2 3.9 1.7e-49 168.6 0.5 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 HEAT PF02985.22 EGO58805.1 - 0.15 12.4 0.0 0.44 10.9 0.0 1.8 1 0 0 1 1 1 0 HEAT repeat CDC45 PF02724.14 EGO58805.1 - 5.7 5.1 9.2 8.5 4.5 9.2 1.2 1 0 0 1 1 1 0 CDC45-like protein RPA43_OB PF17875.1 EGO58805.1 - 6.3 7.4 7.1 2.1 9.0 2.4 2.1 1 1 1 2 2 2 0 RPA43 OB domain in RNA Pol I Aminotran_1_2 PF00155.21 EGO58806.1 - 7.8e-82 275.3 0.0 1.1e-81 274.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGO58806.1 - 0.015 14.1 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Syntaxin-18_N PF10496.9 EGO58808.1 - 1.8e-08 34.5 0.6 4.7e-06 26.8 0.0 2.9 2 0 0 2 2 2 2 SNARE-complex protein Syntaxin-18 N-terminus Chlor_dismutase PF06778.12 EGO58808.1 - 0.022 14.3 1.3 0.19 11.3 0.2 2.3 1 1 0 2 2 2 0 Chlorite dismutase PDE4_UCR PF18100.1 EGO58808.1 - 0.1 13.3 0.2 0.1 13.3 0.2 2.3 3 0 0 3 3 3 0 Phosphodiesterase 4 upstream conserved regions (UCR) SNARE PF05739.19 EGO58808.1 - 0.23 11.5 4.5 0.33 11.0 0.0 3.0 4 0 0 4 4 4 0 SNARE domain DUF3071 PF11268.8 EGO58808.1 - 0.9 9.6 7.4 2.5 8.1 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3071) DUF16 PF01519.16 EGO58808.1 - 1.7 9.2 6.8 1.5 9.3 1.8 2.5 3 0 0 3 3 3 0 Protein of unknown function DUF16 MFS_1 PF07690.16 EGO58809.1 - 3.8e-54 183.9 8.3 3.8e-54 183.9 8.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO58809.1 - 1.3e-10 40.7 7.7 1.3e-10 40.7 7.7 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter Phage_Gp23 PF10669.9 EGO58809.1 - 0.002 18.5 0.3 0.026 14.8 0.1 2.4 2 0 0 2 2 2 1 Protein gp23 (Bacteriophage A118) MscS_TM PF12794.7 EGO58809.1 - 0.3 9.9 4.8 1.2 7.9 4.8 2.2 1 1 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DAGK_cat PF00781.24 EGO58810.1 - 2.6e-23 82.0 0.0 4.2e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NARP1 PF12569.8 EGO58811.1 - 1e-199 664.8 27.0 6.3e-197 655.6 21.2 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 EGO58811.1 - 5.7e-25 87.7 30.0 2.3e-07 31.3 4.9 8.8 9 2 0 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGO58811.1 - 6.7e-21 74.6 32.4 6.6e-08 33.0 0.1 8.5 9 1 1 10 10 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGO58811.1 - 9.3e-16 56.6 39.5 0.00017 21.4 0.1 11.5 12 1 0 12 12 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGO58811.1 - 3.2e-14 52.4 35.0 0.0023 18.6 0.0 12.3 9 4 5 14 14 11 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGO58811.1 - 3.1e-12 46.5 9.9 0.0039 17.3 0.3 6.7 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO58811.1 - 1.1e-11 44.0 20.9 0.021 15.0 0.1 9.6 9 1 0 9 9 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGO58811.1 - 5.1e-11 42.2 12.2 0.00017 21.8 0.0 8.5 10 0 0 10 10 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO58811.1 - 5.1e-11 42.6 16.4 0.00014 22.0 0.4 5.2 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EGO58811.1 - 2.4e-09 36.6 32.8 3e-05 23.6 0.2 9.9 12 0 0 12 12 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGO58811.1 - 4e-09 36.0 16.8 0.00059 19.5 0.1 7.2 7 2 1 8 8 8 2 TPR repeat TPR_12 PF13424.6 EGO58811.1 - 2.3e-08 34.2 15.9 0.46 10.8 0.0 7.9 8 0 0 8 8 7 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGO58811.1 - 5.3e-05 23.2 9.7 4.9 7.3 0.2 5.8 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 EGO58811.1 - 0.0021 18.0 3.7 0.19 11.7 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 EGO58811.1 - 0.015 15.7 1.8 0.015 15.7 1.8 3.5 4 0 0 4 4 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 EGO58811.1 - 0.015 15.1 13.2 5.8 6.9 0.0 6.8 6 0 0 6 6 5 0 Tetratricopeptide repeat Mgr1 PF08602.10 EGO58811.1 - 0.016 14.0 0.4 0.045 12.6 0.4 1.7 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit PPTA PF01239.22 EGO58811.1 - 0.02 14.6 1.9 0.74 9.6 0.0 3.9 4 0 0 4 4 3 0 Protein prenyltransferase alpha subunit repeat HrpB1_HrpK PF09613.10 EGO58811.1 - 0.022 14.4 0.9 0.52 10.0 0.1 3.5 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF913 PF06025.12 EGO58811.1 - 0.023 13.7 0.5 0.049 12.6 0.5 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF5327 PF17261.2 EGO58811.1 - 0.039 14.7 5.1 0.034 14.9 2.3 2.4 2 0 0 2 2 1 0 Family of unknown function (DUF5327) Rapsyn_N PF10579.9 EGO58811.1 - 0.048 13.8 0.7 1 9.5 0.1 3.3 2 1 1 3 3 3 0 Rapsyn N-terminal myristoylation and linker region TPR_7 PF13176.6 EGO58811.1 - 0.096 12.8 9.7 12 6.2 0.2 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat CCDC53 PF10152.9 EGO58811.1 - 0.11 12.9 3.8 0.45 10.9 3.8 2.0 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4919 PF16266.5 EGO58811.1 - 0.29 11.1 6.3 0.65 9.9 0.1 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4919) RNA_pol_Rpc4 PF05132.14 EGO58811.1 - 0.51 10.8 5.8 1.4 9.3 5.8 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 TPR_4 PF07721.14 EGO58811.1 - 0.67 10.7 10.2 41 5.2 0.1 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat Coilin_N PF15862.5 EGO58811.1 - 1.3 8.8 6.8 4.3 7.1 6.8 1.9 1 0 0 1 1 1 0 Coilin N-terminus Presenilin PF01080.17 EGO58811.1 - 6.9 5.3 5.1 13 4.4 5.1 1.4 1 0 0 1 1 1 0 Presenilin Cid2 PF09774.9 EGO58812.1 - 1e-54 185.3 0.0 1.2e-54 185.1 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Ank_2 PF12796.7 EGO58813.1 - 8.7e-26 90.3 1.2 9.5e-10 38.9 0.0 5.1 2 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO58813.1 - 6.1e-25 87.3 3.5 0.0044 17.6 0.0 6.3 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO58813.1 - 1.7e-18 66.4 0.3 0.0091 16.3 0.0 5.5 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO58813.1 - 5.7e-18 63.2 7.6 0.0037 17.6 0.0 8.6 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 EGO58813.1 - 4.5e-13 49.0 14.9 0.0012 19.2 0.0 8.0 8 0 0 8 8 8 3 Ankyrin repeat Zn_clus PF00172.18 EGO58814.1 - 8.4e-08 32.2 11.0 1.6e-07 31.3 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.19 EGO58815.1 - 3.8e-49 166.5 0.0 5.4e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGO58815.1 - 4e-17 62.1 0.0 5.3e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGO58815.1 - 2.6e-05 24.4 0.0 3.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase PF05221.17 EGO58816.1 - 1.4e-132 441.3 0.0 9.1e-75 251.6 0.3 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EGO58816.1 - 2e-82 275.0 2.7 3.1e-82 274.4 2.7 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGO58816.1 - 1.6e-05 24.4 0.1 4e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EGO58816.1 - 0.056 13.0 0.3 0.1 12.2 0.3 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 EGO58816.1 - 0.072 12.8 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 EGO58816.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Urocanase PF01175.18 EGO58816.1 - 0.19 11.4 0.7 0.32 10.6 0.7 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain JAB PF01398.21 EGO58817.1 - 1.9e-08 34.3 2.8 3.5e-07 30.2 2.8 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Mito_carr PF00153.27 EGO58819.1 - 1.3e-48 162.8 1.8 1.8e-20 72.7 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1c PF00749.21 EGO58820.1 - 3.6e-100 334.9 0.0 6.2e-100 334.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGO58820.1 - 6.3e-34 117.4 0.0 3.1e-33 115.1 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Macro PF01661.21 EGO58821.1 - 9.1e-41 138.6 0.3 1.9e-40 137.6 0.3 1.6 1 0 0 1 1 1 1 Macro domain Peptidase_S41 PF03572.18 EGO58823.1 - 0.0023 17.5 0.1 0.0064 16.1 0.0 1.9 2 1 0 2 2 2 1 Peptidase family S41 Zeta_toxin PF06414.12 EGO58823.1 - 0.051 12.8 1.3 0.094 12.0 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 EGO58824.1 - 1.1e-48 165.2 0.1 1.3e-24 87.3 0.0 3.8 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 EGO58824.1 - 6.8e-28 96.6 0.6 6.8e-28 96.6 0.6 2.4 2 0 0 2 2 1 1 Four helical bundle domain AAA_21 PF13304.6 EGO58824.1 - 1e-17 64.9 0.0 0.002 18.0 0.0 5.0 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGO58824.1 - 3.8e-17 62.5 0.2 1.8e-05 24.3 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGO58824.1 - 7.3e-09 35.2 0.0 0.0047 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGO58824.1 - 5.8e-08 32.8 0.0 0.00083 19.3 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGO58824.1 - 1.7e-07 31.3 0.0 0.0025 17.9 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EGO58824.1 - 1.9e-07 31.4 0.1 0.0095 16.2 0.0 4.0 5 0 0 5 5 2 2 AAA domain AAA_23 PF13476.6 EGO58824.1 - 5e-07 30.4 0.3 0.0013 19.3 0.2 3.6 4 0 0 4 4 2 2 AAA domain AAA_28 PF13521.6 EGO58824.1 - 9e-07 29.3 0.2 0.024 14.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 EGO58824.1 - 3e-06 27.2 0.1 0.051 13.3 0.0 3.4 4 0 0 4 4 3 2 AAA ATPase domain Dynamin_N PF00350.23 EGO58824.1 - 5.5e-06 26.5 0.0 0.00095 19.3 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 EGO58824.1 - 6e-06 26.8 1.6 0.41 11.0 0.0 4.4 5 0 0 5 5 4 2 AAA ATPase domain AAA_18 PF13238.6 EGO58824.1 - 6.4e-06 26.7 0.1 0.14 12.7 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 EGO58824.1 - 3.7e-05 24.2 0.0 0.71 10.3 0.0 4.1 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGO58824.1 - 3.7e-05 23.9 0.0 0.53 10.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 EGO58824.1 - 4.4e-05 23.3 0.0 0.036 13.8 0.0 2.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ParcG PF10274.9 EGO58824.1 - 5.6e-05 23.3 1.4 0.81 9.8 0.0 3.3 1 1 2 3 3 3 1 Parkin co-regulated protein RNA_helicase PF00910.22 EGO58824.1 - 8e-05 23.0 0.0 0.79 10.1 0.0 2.9 2 0 0 2 2 2 2 RNA helicase MeaB PF03308.16 EGO58824.1 - 8.5e-05 21.7 2.2 0.21 10.5 0.0 2.9 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_27 PF13514.6 EGO58824.1 - 0.00016 21.3 0.0 0.13 11.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGO58824.1 - 0.00045 20.2 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 EGO58824.1 - 0.00055 19.7 0.0 1.5 8.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 EGO58824.1 - 0.00065 19.0 0.3 1.1 8.4 0.0 2.9 3 0 0 3 3 3 2 G-protein alpha subunit Rad17 PF03215.15 EGO58824.1 - 0.00084 19.3 0.0 1.7 8.6 0.0 2.9 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_14 PF13173.6 EGO58824.1 - 0.0011 19.1 0.0 3 7.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 EGO58824.1 - 0.0012 19.0 1.4 0.92 9.5 0.0 4.0 4 0 0 4 4 4 1 Helicase HerA, central domain AAA_30 PF13604.6 EGO58824.1 - 0.0013 18.5 0.0 3.3 7.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 EGO58824.1 - 0.0022 18.2 0.0 1.1 9.6 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 EGO58824.1 - 0.0039 16.4 0.0 0.23 10.6 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Septin PF00735.18 EGO58824.1 - 0.0043 16.4 0.4 2 7.6 0.0 3.1 3 0 0 3 3 3 1 Septin ATPase_2 PF01637.18 EGO58824.1 - 0.0055 16.7 0.1 3.1 7.6 0.0 3.2 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 EGO58824.1 - 0.006 16.2 0.7 4.1 6.9 0.0 3.2 4 0 0 4 4 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 EGO58824.1 - 0.0063 16.2 0.7 12 5.5 0.0 3.6 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 EGO58824.1 - 0.0081 16.4 0.0 6.8 6.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EGO58824.1 - 0.011 15.5 0.0 7.2 6.3 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EGO58824.1 - 0.015 15.1 0.5 0.79 9.5 0.0 2.9 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PRK PF00485.18 EGO58824.1 - 0.016 15.0 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 EGO58824.1 - 0.017 14.7 0.0 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EGO58824.1 - 0.018 14.8 0.0 5.8 6.6 0.0 2.9 2 0 0 2 2 2 0 IstB-like ATP binding protein MMS19_N PF14500.6 EGO58824.1 - 0.023 14.3 0.5 1.9 8.0 0.2 2.9 2 1 1 3 3 2 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.22 EGO58824.1 - 0.028 14.7 3.7 41 4.8 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat DRIM PF07539.12 EGO58824.1 - 0.041 12.2 1.5 3.9 5.7 0.0 2.6 2 1 0 3 3 3 0 Down-regulated in metastasis Ploopntkinase3 PF18751.1 EGO58824.1 - 0.042 13.8 0.0 9.5 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Cytidylate_kin PF02224.18 EGO58824.1 - 0.05 13.3 0.0 12 5.5 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase Zeta_toxin PF06414.12 EGO58824.1 - 0.055 12.8 0.1 12 5.1 0.0 3.0 3 0 0 3 3 2 0 Zeta toxin Adaptin_N PF01602.20 EGO58824.1 - 0.055 12.0 4.1 0.47 9.0 1.1 2.7 1 1 2 3 3 3 0 Adaptin N terminal region T2SSE PF00437.20 EGO58824.1 - 0.057 12.5 0.0 4.9 6.1 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein EcoEI_R_C PF08463.10 EGO58824.1 - 0.061 13.4 0.2 0.34 11.0 0.1 2.2 1 1 0 2 2 1 0 EcoEI R protein C-terminal Mg_chelatase PF01078.21 EGO58824.1 - 0.066 12.6 0.0 4.4 6.6 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 EGO58824.1 - 0.072 13.0 0.1 16 5.4 0.0 2.7 2 0 0 2 2 2 0 NTPase MukB PF04310.12 EGO58824.1 - 0.076 12.8 0.0 11 5.7 0.0 2.6 2 0 0 2 2 2 0 MukB N-terminal AAA_25 PF13481.6 EGO58824.1 - 0.079 12.5 0.0 8.5 5.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EGO58824.1 - 0.1 11.7 0.0 11 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FeoB_N PF02421.18 EGO58824.1 - 0.11 12.0 0.1 1.3 8.5 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF3385 PF11865.8 EGO58824.1 - 0.2 11.6 0.4 7.4 6.5 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 EGO58824.1 - 0.67 10.4 8.6 2.8 8.4 0.9 3.8 2 1 3 5 5 5 0 HEAT repeats HEAT_EZ PF13513.6 EGO58824.1 - 2.6 8.7 6.2 3.5e+02 1.9 0.0 5.5 6 0 0 6 6 5 0 HEAT-like repeat AAA_13 PF13166.6 EGO58824.1 - 3.7 6.1 11.7 2.5 6.7 0.0 4.2 5 0 0 5 5 5 0 AAA domain CsbD PF05532.12 EGO58825.1 - 6.8e-10 38.7 3.0 3.4e-05 23.7 0.3 2.1 2 0 0 2 2 2 2 CsbD-like Cu-oxidase_2 PF07731.14 EGO58826.1 - 2e-39 134.5 3.0 1.1e-35 122.3 0.0 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGO58826.1 - 1.6e-32 112.0 0.8 8.5e-32 109.7 0.5 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EGO58826.1 - 5.7e-27 94.8 0.0 1.2e-26 93.8 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Methyltransf_24 PF13578.6 EGO58827.1 - 3.1e-09 37.8 0.0 5e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EGO58827.1 - 1.2e-08 34.4 0.0 1.6e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.19 EGO58827.1 - 0.08 12.7 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MFS_1 PF07690.16 EGO58828.1 - 2.1e-28 99.3 41.9 2.6e-28 98.9 39.6 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO58828.1 - 2e-14 53.3 3.9 2e-14 53.3 3.9 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EGO58828.1 - 0.00027 19.5 10.0 0.0018 16.8 9.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3446 PF11928.8 EGO58828.1 - 1.2 9.5 16.2 1.6 9.1 2.1 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain Methyltransf_33 PF10017.9 EGO58829.1 - 8.3e-82 274.8 0.0 1.1e-81 274.4 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FAD_binding_3 PF01494.19 EGO58830.1 - 4.7e-71 239.9 0.0 4.6e-70 236.6 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGO58830.1 - 4.7e-36 124.3 0.0 8.7e-36 123.5 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EGO58830.1 - 1.9e-06 27.3 0.2 0.00027 20.3 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EGO58830.1 - 2.2e-05 23.7 0.0 0.00039 19.5 0.0 2.1 1 1 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 EGO58830.1 - 6.9e-05 22.1 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EGO58830.1 - 7.2e-05 22.5 0.1 0.025 14.1 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EGO58830.1 - 0.0016 17.2 0.0 0.0026 16.5 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EGO58830.1 - 0.0035 17.5 0.0 0.0083 16.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGO58830.1 - 0.0046 16.1 0.0 0.012 14.7 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EGO58830.1 - 0.0077 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO58830.1 - 0.011 16.3 0.1 0.8 10.3 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO58830.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 EGO58830.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Mpv17_PMP22 PF04117.12 EGO58831.1 - 8.9e-20 70.7 0.1 1.9e-19 69.6 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family PGK PF00162.19 EGO58832.1 - 7.9e-153 508.9 0.2 8.9e-153 508.7 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 EGO58832.1 - 0.011 15.8 0.0 0.082 12.9 0.0 2.5 2 1 0 2 2 2 0 PA domain DSS1_SEM1 PF05160.13 EGO58833.1 - 5.1e-23 80.9 19.2 6.7e-23 80.5 19.2 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Cwf_Cwc_15 PF04889.12 EGO58833.1 - 0.11 12.3 10.4 0.11 12.2 10.4 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ArfGap PF01412.18 EGO58833.1 - 0.12 12.5 1.3 0.15 12.1 1.2 1.3 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf DUF3808 PF10300.9 EGO58834.1 - 3.8e-129 431.5 0.0 4.6e-129 431.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.6 EGO58834.1 - 0.18 12.3 9.3 0.1 13.1 0.8 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 EGO58836.1 - 1.2e-08 34.9 0.8 3.7e-08 33.3 0.0 2.2 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO58836.1 - 1.1e-07 32.7 0.2 9.3e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO58836.1 - 0.00011 21.5 0.0 0.012 14.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ntox37 PF15535.6 EGO58836.1 - 0.043 14.3 0.4 0.19 12.2 0.4 2.1 1 0 0 1 1 1 0 Bacterial toxin 37 HRI1 PF16815.5 EGO58838.1 - 7.6e-55 186.1 5.3 1.4e-54 185.3 5.3 1.4 1 1 0 1 1 1 1 Protein HRI1 Methyltransf_23 PF13489.6 EGO58839.1 - 2.8e-18 66.3 0.0 3.6e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO58839.1 - 2.7e-13 50.4 0.0 1.1e-12 48.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO58839.1 - 9.2e-13 48.7 0.0 5.8e-12 46.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO58839.1 - 2.8e-12 47.2 0.0 4.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO58839.1 - 1.1e-09 38.3 0.0 8.9e-09 35.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EGO58839.1 - 0.00023 20.9 0.0 0.0046 16.6 0.0 2.0 2 0 0 2 2 2 1 Nodulation protein S (NodS) RrnaAD PF00398.20 EGO58839.1 - 0.0013 17.9 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 EGO58839.1 - 0.004 16.9 0.0 0.0084 15.9 0.0 1.5 2 0 0 2 2 2 1 Lysine methyltransferase DREV PF05219.12 EGO58839.1 - 0.0091 15.1 0.0 0.082 12.0 0.0 2.0 2 0 0 2 2 2 1 DREV methyltransferase Ubie_methyltran PF01209.18 EGO58839.1 - 0.01 15.2 0.0 0.13 11.6 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGO58839.1 - 0.025 14.1 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 EGO58839.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB adh_short PF00106.25 EGO58841.1 - 2.8e-46 157.5 0.8 3.7e-46 157.1 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO58841.1 - 1.4e-33 116.4 0.2 1.7e-33 116.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO58841.1 - 7e-07 29.3 0.2 1.1e-06 28.7 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGO58841.1 - 0.0005 20.0 0.0 0.0015 18.4 0.0 1.7 1 1 1 2 2 2 1 NAD(P)H-binding ADH_zinc_N PF00107.26 EGO58841.1 - 0.0052 16.8 0.3 0.0094 15.9 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EGO58841.1 - 0.0095 15.4 0.2 0.019 14.4 0.2 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGO58841.1 - 0.077 12.1 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Gar1 PF04410.14 EGO58842.1 - 5.1e-33 114.0 0.0 9.4e-33 113.2 0.0 1.4 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Colicin_immun PF09204.10 EGO58843.1 - 0.011 16.3 0.2 4.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity PqqD PF05402.12 EGO58843.1 - 0.15 12.4 0.8 1.8 8.9 0.1 2.8 2 1 1 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) Glyco_hydro_61 PF03443.14 EGO58845.1 - 4.7e-66 222.6 0.2 5.7e-66 222.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 fn3 PF00041.21 EGO58845.1 - 0.075 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Fibronectin type III domain DUF5624 PF18538.1 EGO58845.1 - 0.11 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) HET PF06985.11 EGO58846.1 - 6.6e-30 104.4 2.4 1.6e-29 103.2 0.1 2.3 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Mpp10 PF04006.12 EGO58846.1 - 0.00028 19.5 9.8 0.00039 19.0 9.8 1.1 1 0 0 1 1 1 1 Mpp10 protein DUF3306 PF11748.8 EGO58846.1 - 0.0018 19.1 3.8 0.0032 18.3 3.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3306) SDA1 PF05285.12 EGO58846.1 - 0.0022 17.5 12.9 0.0031 17.0 12.9 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 EGO58846.1 - 0.0072 15.7 9.2 0.01 15.3 9.2 1.1 1 0 0 1 1 1 1 BUD22 Trypan_PARP PF05887.11 EGO58846.1 - 0.014 15.4 9.7 0.025 14.6 9.7 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CPSF100_C PF13299.6 EGO58846.1 - 0.042 14.0 3.0 0.071 13.3 3.0 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 EGO58846.1 - 0.075 12.2 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Vfa1 PF08432.10 EGO58846.1 - 0.12 12.7 5.3 0.19 12.1 5.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SpoIIP PF07454.11 EGO58846.1 - 0.14 11.6 3.3 0.21 11.0 3.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) STAC2_u1 PF16664.5 EGO58846.1 - 0.2 12.1 1.7 0.49 10.9 1.7 1.6 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Sigma70_ner PF04546.13 EGO58846.1 - 0.27 11.1 18.1 0.46 10.3 18.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Tim54 PF11711.8 EGO58846.1 - 0.31 9.8 6.1 0.46 9.2 6.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sporozoite_P67 PF05642.11 EGO58846.1 - 0.48 8.4 4.8 0.74 7.8 4.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Presenilin PF01080.17 EGO58846.1 - 0.53 9.0 1.0 0.79 8.4 1.0 1.2 1 0 0 1 1 1 0 Presenilin MRNIP PF15749.5 EGO58846.1 - 0.56 11.0 5.9 1.1 10.0 5.9 1.4 1 0 0 1 1 1 0 MRN-interacting protein Pox_Ag35 PF03286.14 EGO58846.1 - 0.62 9.8 13.4 1 9.1 13.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TRAP_alpha PF03896.16 EGO58846.1 - 0.75 8.9 8.5 1.1 8.4 8.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF913 PF06025.12 EGO58846.1 - 1.1 8.2 2.5 1.6 7.6 2.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 EGO58846.1 - 1.3 7.1 23.0 1.8 6.6 23.0 1.1 1 0 0 1 1 1 0 Nop14-like family RPN2_C PF18004.1 EGO58846.1 - 1.6 8.7 11.6 2.4 8.1 11.6 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain V_ATPase_I PF01496.19 EGO58846.1 - 1.7 6.5 3.6 2.2 6.1 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNA_pol_Rpc4 PF05132.14 EGO58846.1 - 2 8.8 3.8 3.7 7.9 3.8 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DNA_pol_phi PF04931.13 EGO58846.1 - 2.4 6.2 29.8 3.3 5.7 29.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EGO58846.1 - 2.4 6.4 16.4 3.4 5.9 16.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 EGO58846.1 - 2.5 7.4 4.8 3.9 6.8 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Afi1 PF07792.12 EGO58846.1 - 3.2 8.2 8.1 5.7 7.4 8.1 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2722 PF10846.8 EGO58846.1 - 3.3 6.5 4.7 4.7 6.0 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RR_TM4-6 PF06459.12 EGO58846.1 - 3.4 7.4 11.7 5.3 6.8 11.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.13 EGO58846.1 - 4.3 6.2 23.8 6.3 5.7 23.8 1.1 1 0 0 1 1 1 0 Paf1 DUF2457 PF10446.9 EGO58846.1 - 5.3 6.1 31.6 8.1 5.5 31.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Utp14 PF04615.13 EGO58846.1 - 6.1 5.3 16.1 8.4 4.8 16.1 1.1 1 0 0 1 1 1 0 Utp14 protein RXT2_N PF08595.11 EGO58846.1 - 8 6.5 12.9 14 5.7 12.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 EGO58846.1 - 8.7 5.6 21.8 15 4.7 21.8 1.3 1 0 0 1 1 1 0 NOA36 protein zf-RING_5 PF14634.6 EGO58847.1 - 0.0012 18.8 5.1 0.0012 18.8 5.1 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO58847.1 - 0.0027 17.6 2.9 0.0027 17.6 2.9 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO58847.1 - 0.011 15.5 1.3 0.011 15.5 1.3 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO58847.1 - 0.012 15.9 6.2 0.012 15.9 6.2 3.6 3 1 0 3 3 3 0 Ring finger domain zf-C3HC4_3 PF13920.6 EGO58847.1 - 0.029 14.2 15.9 0.25 11.3 6.6 3.6 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO58847.1 - 0.31 10.9 15.7 0.12 12.2 4.1 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGO58847.1 - 1.9 8.7 9.4 0.093 12.9 0.7 3.0 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Acetyltransf_7 PF13508.7 EGO58848.1 - 2.6e-07 31.0 0.0 4.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGO58848.1 - 5e-06 26.5 0.0 9.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGO58848.1 - 1.4e-05 25.2 0.0 2.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO58848.1 - 0.00033 20.9 0.0 0.00062 20.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGO58848.1 - 0.0017 18.2 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 EGO58848.1 - 0.077 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 EGO58848.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase OPT PF03169.15 EGO58849.1 - 1.5e-182 608.6 51.2 1.7e-182 608.4 51.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SNF5 PF04855.12 EGO58850.1 - 2.3e-95 318.9 0.0 3e-95 318.6 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 EGO58850.1 - 0.00031 20.3 3.6 0.00072 19.1 3.6 1.7 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 EGO58850.1 - 0.39 10.5 8.8 2.3 8.0 4.0 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain Exo_endo_phos PF03372.23 EGO58852.1 - 5e-07 29.5 0.3 7.2e-07 28.9 0.3 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Helo_like_N PF17111.5 EGO58853.1 - 2.9e-08 33.3 0.0 4.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Pex2_Pex12 PF04757.14 EGO58855.1 - 0.1 12.2 0.2 0.15 11.6 0.2 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region RNA_ligase PF09414.10 EGO58856.1 - 7.8e-24 84.8 0.0 1.4e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DAAD PF18752.1 EGO58858.1 - 0.038 13.8 0.1 0.044 13.6 0.1 1.1 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase NAD_binding_1 PF00175.21 EGO58859.1 - 8.3e-29 100.4 0.0 1.2e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGO58859.1 - 5.1e-16 58.8 0.0 7.9e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGO58859.1 - 1.9e-08 34.6 0.0 1.2e-05 25.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain MFS_1 PF07690.16 EGO58860.1 - 1.1e-29 103.4 23.8 1.1e-29 103.4 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO58860.1 - 6.7e-13 48.3 5.0 6.7e-13 48.3 5.0 1.9 3 0 0 3 3 3 1 Sugar (and other) transporter COX7C PF02935.16 EGO58860.1 - 0.12 12.7 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc DEAD PF00270.29 EGO58861.1 - 9.9e-44 149.2 0.1 1.6e-43 148.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO58861.1 - 1.1e-16 61.1 0.0 6.6e-16 58.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGO58861.1 - 1.9e-13 50.4 0.1 3.9e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGO58861.1 - 7.5e-06 26.1 0.1 7.2e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Zn_clus PF00172.18 EGO58862.1 - 0.01 15.9 10.4 0.018 15.2 10.4 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MPP6 PF10175.9 EGO58862.1 - 0.021 15.4 0.3 0.04 14.4 0.0 1.5 2 0 0 2 2 2 0 M-phase phosphoprotein 6 Ribosomal_60s PF00428.19 EGO58862.1 - 0.026 15.1 8.0 0.026 15.1 8.0 3.4 5 0 0 5 5 5 0 60s Acidic ribosomal protein FAM176 PF14851.6 EGO58862.1 - 0.045 13.4 1.6 0.11 12.2 1.6 1.6 1 0 0 1 1 1 0 FAM176 family Radial_spoke PF04712.12 EGO58862.1 - 0.18 10.7 4.5 0.36 9.7 4.5 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4632 PF15451.6 EGO58862.1 - 0.41 10.7 2.7 0.57 10.3 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) Sugar_tr PF00083.24 EGO58863.1 - 2.3e-89 300.3 18.5 2.7e-89 300.1 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO58863.1 - 7.1e-17 61.4 20.6 7.1e-17 61.4 20.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGO58863.1 - 1.8e-05 23.5 20.6 0.00022 19.9 2.7 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein Folate_carrier PF01770.18 EGO58863.1 - 0.014 14.2 3.0 0.046 12.5 3.0 1.7 1 1 0 1 1 1 0 Reduced folate carrier MFS_1_like PF12832.7 EGO58863.1 - 2 7.2 12.9 0.12 11.2 3.7 2.2 2 0 0 2 2 2 0 MFS_1 like family Alpha-amylase PF00128.24 EGO58864.1 - 2.7e-110 369.1 0.0 3.6e-110 368.7 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 EGO58864.1 - 0.0011 18.1 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Cellulase PF00150.18 EGO58864.1 - 0.0041 16.6 0.2 0.0088 15.5 0.1 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PBP PF01161.20 EGO58865.1 - 3.4e-09 37.1 0.0 4.5e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein LysM PF01476.20 EGO58866.1 - 3.4e-06 27.0 0.0 9.2e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 LysM domain p450 PF00067.22 EGO58867.1 - 1.5e-60 205.3 0.0 1.9e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L1 PF00687.21 EGO58868.1 - 1.2e-64 217.9 2.3 1.2e-64 217.9 2.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Palm_thioest PF02089.15 EGO58870.1 - 2.1e-77 260.2 0.0 2.5e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PH_9 PF15410.6 EGO58870.1 - 0.03 14.7 0.0 0.052 13.9 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain DUF915 PF06028.11 EGO58870.1 - 0.18 11.1 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) CFEM PF05730.11 EGO58871.1 - 0.0004 20.4 5.7 0.00093 19.3 5.7 1.6 1 1 0 1 1 1 1 CFEM domain DHO_dh PF01180.21 EGO58872.1 - 6.1e-68 229.2 0.0 1.2e-67 228.2 0.0 1.4 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.17 EGO58872.1 - 0.00083 18.9 0.6 0.7 9.3 0.1 2.3 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.18 EGO58872.1 - 0.019 14.0 0.8 0.088 11.8 0.5 2.2 2 1 0 2 2 2 0 FMN-dependent dehydrogenase SSP160 PF06933.11 EGO58872.1 - 0.14 10.3 9.7 0.21 9.7 9.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 EGO58872.1 - 7.2 6.6 9.3 16 5.5 9.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mpv17_PMP22 PF04117.12 EGO58873.1 - 3.9e-19 68.6 1.1 3.9e-19 68.6 1.1 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family MFS_1 PF07690.16 EGO58874.1 - 1.3e-15 57.2 29.5 1.8e-15 56.8 20.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 EGO58874.1 - 5.5e-08 32.7 2.9 8.6e-08 32.0 1.7 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 zf-RING_2 PF13639.6 EGO58875.1 - 4.3e-08 33.4 7.8 8.2e-08 32.5 7.8 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EGO58875.1 - 1.2e-06 28.6 7.4 3.8e-06 27.0 7.4 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 EGO58875.1 - 0.00031 20.7 2.0 0.00073 19.6 2.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 EGO58875.1 - 0.00047 20.2 5.5 0.00095 19.2 5.5 1.6 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.7 EGO58875.1 - 0.0007 19.8 7.8 0.0019 18.4 7.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGO58875.1 - 0.002 17.9 8.5 0.0043 16.9 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Arnt_C PF18583.1 EGO58875.1 - 0.072 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain Zn_ribbon_17 PF17120.5 EGO58875.1 - 0.11 12.1 5.0 0.22 11.2 5.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EGO58875.1 - 0.17 11.8 6.9 0.45 10.4 6.8 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EGO58875.1 - 0.19 12.1 6.8 0.34 11.3 6.8 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.6 EGO58875.1 - 0.24 11.3 9.2 0.64 9.9 9.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 EGO58875.1 - 0.87 9.5 4.6 0.48 10.3 2.1 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_UBOX PF13445.6 EGO58875.1 - 0.87 9.7 5.3 2.5 8.2 5.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EGO58875.1 - 2 8.3 8.5 1.2 9.1 3.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 IBR PF01485.21 EGO58875.1 - 4.8 7.5 5.8 12 6.2 5.9 1.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain PHD PF00628.29 EGO58875.1 - 5 7.1 6.4 9.9 6.1 6.4 1.5 1 0 0 1 1 1 0 PHD-finger DUF913 PF06025.12 EGO58877.1 - 0.76 8.7 4.2 7 5.5 0.8 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Orf78 PF06024.12 EGO58879.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Sin_N PF04801.13 EGO58881.1 - 2.4e-06 27.1 0.0 6.1e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Sin-like protein conserved region PAT1 PF09770.9 EGO58883.1 - 0 1270.4 12.5 0 1270.3 12.5 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.16 EGO58884.1 - 1.9e-130 434.9 6.3 2.3e-130 434.6 6.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.25 EGO58885.1 - 3.6e-28 97.4 0.6 4.5e-28 97.2 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acyl-CoA_dh_1 PF00441.24 EGO58886.1 - 1.3e-39 135.8 4.4 2e-39 135.2 4.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGO58886.1 - 1.7e-29 102.8 0.5 3.9e-29 101.6 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGO58886.1 - 1.2e-24 86.3 0.0 2.5e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGO58886.1 - 1.2e-16 61.2 3.0 2e-16 60.5 0.7 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EGO58886.1 - 0.0013 18.4 0.1 0.0046 16.7 0.1 1.8 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 EGO58886.1 - 0.0059 16.6 0.1 0.019 15.0 0.0 1.9 2 0 0 2 2 2 1 Staphylococcal AgrD protein Pkinase PF00069.25 EGO58887.1 - 2e-60 204.4 0.1 6.1e-60 202.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO58887.1 - 1.7e-35 122.6 0.0 3.2e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 EGO58887.1 - 3.8e-21 75.0 21.9 2.6e-12 46.7 5.8 2.8 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.22 EGO58887.1 - 2e-20 72.4 25.8 3e-12 46.2 10.1 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 EGO58887.1 - 2.6e-14 53.6 1.0 1.1e-13 51.6 1.0 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EGO58887.1 - 0.042 13.2 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like She9_MDM33 PF05546.11 EGO58888.1 - 1.7e-79 266.2 6.5 1.7e-79 266.2 6.5 1.9 2 0 0 2 2 2 1 She9 / Mdm33 family Pex14_N PF04695.13 EGO58888.1 - 0.019 15.6 1.8 0.019 15.6 1.8 3.4 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PsbH PF00737.20 EGO58888.1 - 0.29 10.9 1.0 0.53 10.1 1.0 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein DUF4618 PF15397.6 EGO58888.1 - 0.95 8.8 8.1 9.1 5.6 2.8 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) RAP1 PF07218.11 EGO58888.1 - 1 7.6 6.7 1.4 7.2 6.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TMEM171 PF15471.6 EGO58888.1 - 1.1 8.2 12.4 1.8 7.5 12.4 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 PRCC PF10253.9 EGO58888.1 - 7.1 7.4 30.8 10 6.9 2.4 2.4 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting DUF4448 PF14610.6 EGO58889.1 - 0.042 13.6 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Saf_2TM PF18303.1 EGO58889.1 - 0.058 13.0 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain MMR_HSR1 PF01926.23 EGO58890.1 - 3e-07 30.5 0.1 0.011 15.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO58890.1 - 0.00016 21.6 0.0 0.00042 20.2 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 EGO58890.1 - 0.00038 19.8 0.0 0.53 9.6 0.0 2.7 2 0 0 2 2 2 2 AIG1 family AAA_16 PF13191.6 EGO58890.1 - 0.00061 20.2 0.0 0.002 18.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 EGO58890.1 - 0.0019 18.2 0.1 0.14 12.2 0.0 3.0 3 0 0 3 3 3 1 Dynamin family AAA_29 PF13555.6 EGO58890.1 - 0.0057 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.18 EGO58890.1 - 0.0077 15.5 0.1 0.066 12.5 0.2 2.5 2 1 0 2 2 2 1 Septin AAA_23 PF13476.6 EGO58890.1 - 0.016 15.7 2.1 0.27 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 EGO58890.1 - 0.03 13.5 0.0 0.071 12.3 0.0 1.8 1 1 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 EGO58890.1 - 0.08 13.2 0.0 0.41 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGO58890.1 - 0.098 13.2 0.0 0.3 11.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter TniB PF05621.11 EGO58890.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein GTP_EFTU PF00009.27 EGO58890.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EGO58890.1 - 0.14 11.9 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain SNO PF01174.19 EGO58891.1 - 4.3e-53 179.9 0.0 3.1e-52 177.2 0.0 1.9 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EGO58891.1 - 9.3e-10 38.4 0.0 6e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 EGO58891.1 - 0.0019 17.8 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 EGO58891.1 - 0.003 17.4 0.1 0.051 13.3 0.1 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 EGO58891.1 - 0.0096 15.7 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family SOR_SNZ PF01680.17 EGO58892.1 - 1.2e-103 345.3 7.6 1.7e-103 344.8 7.6 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EGO58892.1 - 1.2e-06 28.0 10.5 0.00083 18.7 1.7 2.6 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 EGO58892.1 - 0.00017 21.1 0.7 0.0088 15.5 0.2 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein Dus PF01207.17 EGO58892.1 - 0.00021 20.5 0.3 0.29 10.2 0.1 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 EGO58892.1 - 0.00095 18.4 2.3 0.024 13.8 0.0 3.1 2 2 2 4 4 4 1 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 EGO58892.1 - 0.012 15.0 0.8 0.27 10.6 0.1 2.6 2 1 0 2 2 2 0 Thiamine monophosphate synthase NMO PF03060.15 EGO58892.1 - 0.95 8.8 10.9 1.3 8.3 4.3 2.4 2 0 0 2 2 2 0 Nitronate monooxygenase FAR1 PF03101.15 EGO58893.1 - 8.9e-09 35.9 0.8 8.9e-09 35.9 0.8 1.7 2 0 0 2 2 2 1 FAR1 DNA-binding domain DUF2730 PF10805.8 EGO58893.1 - 0.1 12.7 0.5 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Presenilin PF01080.17 EGO58893.1 - 0.62 8.8 4.7 0.58 8.9 4.7 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 EGO58893.1 - 3.8 6.1 10.8 4.1 6.0 10.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF812 PF05667.11 EGO58893.1 - 4.4 6.1 12.1 6.5 5.5 12.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ALG3 PF05208.13 EGO58894.1 - 9e-150 499.0 11.6 1e-149 498.8 11.6 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.19 EGO58895.1 - 2.3e-21 75.4 0.2 3.1e-21 74.9 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Terminase_6 PF03237.15 EGO58895.1 - 0.0036 17.0 0.0 0.0041 16.8 0.0 1.1 1 0 0 1 1 1 1 Terminase-like family SNN_linker PF09050.10 EGO58895.1 - 0.28 11.0 5.6 0.45 10.3 0.3 2.6 2 0 0 2 2 2 0 Stannin unstructured linker HAD PF12710.7 EGO58896.1 - 5.9e-24 85.5 0.0 7.4e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EGO58896.1 - 0.00041 19.8 0.0 0.0037 16.7 0.0 2.0 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 EGO58896.1 - 0.0018 17.8 0.0 0.0026 17.3 0.0 1.4 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 EGO58896.1 - 0.012 16.0 0.3 1.9 8.8 0.0 3.1 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Thioredoxin PF00085.20 EGO58898.1 - 2.6e-27 94.8 0.1 3.2e-27 94.5 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGO58898.1 - 1.9e-07 31.5 0.1 1.1e-06 29.1 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGO58898.1 - 4.8e-06 26.1 0.0 5.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EGO58898.1 - 3.9e-05 23.9 0.0 0.026 14.9 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 EGO58898.1 - 7.4e-05 22.5 0.0 8.6e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EGO58898.1 - 0.014 15.1 0.2 0.28 10.9 0.1 2.0 1 1 1 2 2 2 0 Redoxin AhpC-TSA PF00578.21 EGO58898.1 - 0.041 13.8 0.1 0.064 13.2 0.0 1.4 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_5 PF13743.6 EGO58898.1 - 0.054 13.2 0.0 0.099 12.3 0.0 1.4 1 1 1 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 EGO58898.1 - 0.091 13.0 0.3 0.29 11.4 0.1 1.9 1 1 1 2 2 2 0 Glutaredoxin Thioredoxin_7 PF13899.6 EGO58898.1 - 0.095 12.9 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like DAO PF01266.24 EGO58900.1 - 1.5e-37 130.1 1.7 1.7e-37 129.9 1.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO58900.1 - 2.7e-05 23.4 0.2 4.2e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGO58900.1 - 0.0001 22.5 0.2 0.00026 21.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGO58900.1 - 0.00072 18.9 0.3 0.00072 18.9 0.3 2.1 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.14 EGO58900.1 - 0.00079 18.7 0.9 0.0014 17.9 0.3 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO58900.1 - 0.0076 15.5 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGO58900.1 - 0.0079 15.3 0.2 0.012 14.8 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EGO58900.1 - 0.017 15.6 0.1 0.039 14.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO58900.1 - 0.023 13.4 0.7 0.033 12.9 0.7 1.1 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 EGO58900.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EGO58900.1 - 0.073 12.4 1.0 0.11 11.8 1.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 EGO58900.1 - 0.086 12.5 0.5 0.16 11.6 0.5 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 EGO58900.1 - 0.096 11.9 0.4 0.15 11.3 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 EGO58900.1 - 0.13 11.1 0.4 0.19 10.5 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_2 PF03446.15 EGO58901.1 - 2.7e-36 125.1 0.0 5e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGO58901.1 - 4.3e-30 104.4 0.4 9.3e-30 103.4 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EGO58901.1 - 2.5e-07 31.2 0.1 1.5e-06 28.7 0.0 2.2 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 EGO58901.1 - 1.5e-06 27.4 0.0 2.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 EGO58901.1 - 2.9e-05 24.9 0.0 7.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 EGO58901.1 - 0.0011 19.4 0.0 0.0023 18.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 EGO58901.1 - 0.024 14.9 0.1 0.087 13.1 0.0 2.0 3 0 0 3 3 3 0 TrkA-N domain Shikimate_DH PF01488.20 EGO58901.1 - 0.028 14.5 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EGO58901.1 - 0.085 12.7 0.1 0.26 11.2 0.1 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KilA-N PF04383.13 EGO58902.1 - 0.0024 17.7 0.0 0.011 15.6 0.0 1.9 1 1 1 2 2 2 1 KilA-N domain Hamartin PF04388.12 EGO58902.1 - 0.024 13.3 18.6 0.031 13.0 18.6 1.1 1 0 0 1 1 1 0 Hamartin protein Rho_GDI PF02115.17 EGO58903.1 - 4e-65 219.2 0.0 4.7e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor E1_DerP2_DerF2 PF02221.15 EGO58903.1 - 0.06 13.8 0.0 0.12 12.8 0.0 1.6 1 1 0 1 1 1 0 ML domain Metallophos PF00149.28 EGO58904.1 - 1.4e-36 126.9 0.6 1.9e-36 126.5 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGO58904.1 - 0.037 14.5 0.2 0.094 13.2 0.2 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EGO58904.1 - 0.15 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain zf-CCHC PF00098.23 EGO58906.1 - 7.7e-05 22.6 0.7 0.00017 21.5 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGO58906.1 - 0.23 11.2 0.2 0.38 10.5 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_L37 PF08561.10 EGO58907.1 - 1.4 9.4 9.4 19 5.8 6.1 2.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 Nuf2 PF03800.14 EGO58911.1 - 9.8e-44 148.8 0.0 3.2e-43 147.2 0.0 1.9 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 EGO58911.1 - 1.2e-36 125.3 17.9 1.2e-36 125.3 17.9 4.6 3 2 2 5 5 5 1 Designed helical repeat protein 10 domain VPS11_C PF12451.8 EGO58911.1 - 0.04 14.1 1.9 8.5 6.7 0.1 3.8 2 1 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Transformer PF06495.11 EGO58911.1 - 6.6 6.8 7.9 16 5.5 7.9 1.7 1 0 0 1 1 1 0 Fruit fly transformer protein Adaptin_N PF01602.20 EGO58913.1 - 2.3e-106 356.5 0.0 2.8e-106 356.2 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGO58913.1 - 2.1e-15 57.1 0.5 1.4e-14 54.5 0.0 2.5 3 1 0 3 3 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGO58913.1 - 3e-10 40.4 8.2 1.1e-05 25.7 0.0 5.4 4 2 1 5 5 5 2 HEAT repeats HEAT PF02985.22 EGO58913.1 - 2.6e-08 33.4 0.4 0.027 14.7 0.0 5.6 5 0 0 5 5 4 1 HEAT repeat HEAT_EZ PF13513.6 EGO58913.1 - 0.00043 20.7 5.6 0.93 10.1 0.0 4.6 5 0 0 5 5 4 2 HEAT-like repeat Cohesin_HEAT PF12765.7 EGO58913.1 - 0.017 15.4 0.5 0.11 12.8 0.0 2.6 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion SDA1 PF05285.12 EGO58913.1 - 0.073 12.5 23.9 0.11 11.9 23.9 1.2 1 0 0 1 1 1 0 SDA1 RTP1_C1 PF10363.9 EGO58913.1 - 0.075 13.2 0.0 2 8.7 0.0 2.9 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 RR_TM4-6 PF06459.12 EGO58913.1 - 0.22 11.3 12.0 0.34 10.7 12.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 EGO58913.1 - 0.43 8.7 27.3 0.67 8.1 27.3 1.2 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.13 EGO58913.1 - 1.1 9.5 16.3 1.8 8.8 16.3 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated RNA_pol_Rpc4 PF05132.14 EGO58913.1 - 1.1 9.6 6.3 2.2 8.7 6.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2457 PF10446.9 EGO58913.1 - 2.1 7.4 32.8 3.1 6.8 32.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF5524 PF17662.1 EGO58913.1 - 3 7.1 8.8 4.9 6.4 8.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5524) DUF4746 PF15928.5 EGO58913.1 - 3.5 6.9 17.2 5.8 6.2 17.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RXT2_N PF08595.11 EGO58913.1 - 4.5 7.3 15.6 8 6.5 13.9 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Cnd3 PF12719.7 EGO58913.1 - 5.3 6.1 5.4 1 8.5 0.0 2.4 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Pox_Ag35 PF03286.14 EGO58913.1 - 7.7 6.3 20.1 16 5.2 20.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Paf1 PF03985.13 EGO58913.1 - 7.8 5.4 28.4 11 4.8 28.4 1.1 1 0 0 1 1 1 0 Paf1 DUF2244 PF10003.9 EGO58914.1 - 1.4 8.6 4.4 1.8 8.2 4.4 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Syndecan PF01034.20 EGO58914.1 - 6 6.9 5.6 12 5.9 5.6 1.4 1 0 0 1 1 1 0 Syndecan domain zf-C2HE PF16278.5 EGO58916.1 - 2.5e-18 66.3 0.5 5.5e-18 65.2 0.5 1.6 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 EGO58916.1 - 8.9e-16 58.4 5.2 1.6e-14 54.3 5.2 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EGO58916.1 - 8.1e-15 55.4 0.3 1.6e-14 54.4 0.3 1.5 1 0 0 1 1 1 1 HIT domain COesterase PF00135.28 EGO58917.1 - 5e-86 289.6 0.0 2.7e-79 267.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EGO58917.1 - 5.4e-05 23.1 0.1 0.00033 20.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold PI31_Prot_N PF11566.8 EGO58921.1 - 3e-64 215.7 0.0 3.6e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EGO58921.1 - 1.9e-18 67.4 19.2 1.9e-18 67.4 19.2 3.5 3 1 0 3 3 3 1 PI31 proteasome regulator HORMA PF02301.18 EGO58922.1 - 1.4e-10 41.2 0.0 1.9e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 HORMA domain IBN_N PF03810.19 EGO58923.1 - 2e-07 30.8 0.1 2.4e-06 27.3 0.0 3.0 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGO58923.1 - 0.00017 21.7 0.0 0.0047 17.0 0.0 2.8 2 0 0 2 2 2 1 Exportin 1-like protein STAS_2 PF13466.6 EGO58923.1 - 0.19 12.1 1.7 0.43 11.0 0.2 2.4 2 0 0 2 2 2 0 STAS domain RhoGEF PF00621.20 EGO58924.1 - 2.3e-23 83.4 0.2 1.7e-22 80.5 0.0 2.3 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.8 EGO58924.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) ING PF12998.7 EGO58924.1 - 1.1 9.9 6.6 1.6 9.3 1.4 3.0 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Laminin_II PF06009.12 EGO58924.1 - 1.7 8.7 7.0 0.42 10.6 1.8 2.5 1 1 1 2 2 2 0 Laminin Domain II DUF885 PF05960.11 EGO58924.1 - 1.9 8.0 7.2 4.7 6.7 7.2 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) FUSC PF04632.12 EGO58924.1 - 2.2 6.7 10.5 4.8 5.6 10.5 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Apolipoprotein PF01442.18 EGO58924.1 - 2.5 7.9 26.5 1.1 9.1 22.1 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4404 PF14357.6 EGO58924.1 - 4.1 8.1 9.5 0.78 10.4 1.4 3.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) DUF1690 PF07956.11 EGO58924.1 - 4.4 7.7 14.1 2.2 8.7 8.6 2.9 2 1 0 2 2 2 0 Protein of Unknown function (DUF1690) DUF1533 PF07550.11 EGO58925.1 - 0.038 13.9 1.5 8.2 6.4 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1533) DUF4781 PF16013.5 EGO58925.1 - 1.5 7.5 4.6 2.3 6.9 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Pkinase PF00069.25 EGO58926.1 - 1.7e-14 53.8 0.0 6.1e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO58926.1 - 0.0085 15.4 0.0 0.039 13.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase HET PF06985.11 EGO58928.1 - 1.7e-26 93.3 0.0 3.6e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 EGO58928.1 - 5.7e-20 71.8 0.0 1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO58928.1 - 1.9e-14 53.6 0.0 3.1e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Dcc1 PF09724.9 EGO58929.1 - 8.7e-09 35.1 0.1 1e-08 34.9 0.1 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Rad4 PF03835.15 EGO58931.1 - 1.8e-36 125.0 0.1 7.7e-36 123.0 0.1 2.1 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EGO58931.1 - 2.3e-27 95.2 0.3 4.8e-27 94.2 0.3 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EGO58931.1 - 2.9e-20 71.8 0.1 6e-20 70.8 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EGO58931.1 - 5.3e-16 59.3 0.5 5.3e-16 59.3 0.5 5.9 5 3 1 6 6 6 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EGO58931.1 - 0.02 15.4 0.0 0.12 12.8 0.0 2.3 2 1 0 2 2 2 0 Transglutaminase-like superfamily zf-AN1 PF01428.16 EGO58932.1 - 1.3e-22 79.7 27.3 9.5e-12 44.9 5.9 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 EGO58932.1 - 0.002 18.3 16.5 0.028 14.7 2.9 2.5 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 EGO58932.1 - 0.023 15.0 11.6 0.025 14.9 2.5 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain MTP18 PF10558.9 EGO58933.1 - 1e-83 279.5 0.0 1.9e-83 278.6 0.0 1.4 2 0 0 2 2 2 1 Mitochondrial 18 KDa protein (MTP18) ATP19 PF11022.8 EGO58934.1 - 4.7e-19 68.5 0.1 7.8e-19 67.8 0.1 1.4 1 0 0 1 1 1 1 ATP synthase subunit K YafQ_toxin PF15738.5 EGO58936.1 - 0.087 13.2 0.5 0.18 12.2 0.3 1.6 2 0 0 2 2 2 0 Bacterial toxin of type II toxin-antitoxin system, YafQ Exonuc_VII_L PF02601.15 EGO58937.1 - 0.2 11.2 4.8 0.23 11.0 4.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4047 PF13256.6 EGO58937.1 - 0.37 11.0 3.8 0.55 10.4 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Mod_r PF07200.13 EGO58937.1 - 0.76 9.9 10.2 1.2 9.2 9.3 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein HIP1_clath_bdg PF16515.5 EGO58937.1 - 1.1 10.0 12.9 1.3 9.7 9.4 2.3 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 EGO58937.1 - 1.2 9.7 11.0 1.4 9.4 9.9 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region Atg14 PF10186.9 EGO58937.1 - 1.3 8.1 10.4 1.1 8.2 9.3 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF883 PF05957.13 EGO58937.1 - 3.8 8.2 7.5 2.6 8.7 3.2 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) HTH_ABP1_N PF18107.1 EGO58938.1 - 6e-25 86.7 1.9 1.9e-24 85.1 1.9 1.9 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 EGO58938.1 - 2.4e-17 62.7 3.0 1.2e-16 60.5 0.3 2.9 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain Ndc1_Nup PF09531.10 EGO58938.1 - 1.7 7.3 8.8 2.3 6.8 0.7 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup SH3_1 PF00018.28 EGO58939.1 - 1.6e-28 98.0 0.0 1.6e-13 50.0 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EGO58939.1 - 1.8e-19 69.3 0.2 1e-09 38.1 0.1 3.1 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 EGO58939.1 - 5.3e-14 52.2 0.0 1.3e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 EGO58939.1 - 1.2e-12 47.3 0.0 1.1e-07 31.4 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain PB1 PF00564.24 EGO58939.1 - 5.5e-09 35.8 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 PB1 domain SAC3_GANP PF03399.16 EGO58940.1 - 1.1e-24 87.4 5.4 1.2e-22 80.7 5.4 2.3 1 1 0 1 1 1 1 SAC3/GANP family COX5A PF02284.16 EGO58940.1 - 0.051 13.6 0.2 0.16 12.0 0.2 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va CSN8_PSD8_EIF3K PF10075.9 EGO58940.1 - 0.088 12.8 0.1 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family EAP30 PF04157.16 EGO58941.1 - 4.6e-44 150.5 0.0 6e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 EGO58941.1 - 3.5e-23 81.6 0.0 6.3e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 EGO58941.1 - 7.6e-23 79.7 1.3 7.6e-23 79.7 1.3 2.5 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EGO58941.1 - 0.0001 22.3 2.7 0.019 15.0 0.2 2.4 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 EGO58941.1 - 0.0029 16.9 10.5 0.01 15.1 0.6 2.6 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.20 EGO58941.1 - 0.025 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 GRAM domain Mu-like_Com PF10122.9 EGO58941.1 - 0.18 11.3 0.3 0.53 9.8 0.3 1.7 1 0 0 1 1 1 0 Mu-like prophage protein Com DZR PF12773.7 EGO58941.1 - 1.8 8.6 6.0 0.34 11.0 0.5 2.3 3 1 0 3 3 3 0 Double zinc ribbon DUF3716 PF12511.8 EGO58944.1 - 1.1e-31 108.7 11.7 1e-15 57.5 2.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3716) Macro PF01661.21 EGO58944.1 - 0.00082 19.4 0.3 0.077 13.0 0.1 2.6 2 0 0 2 2 2 1 Macro domain DUF5520 PF17658.1 EGO58944.1 - 0.23 10.5 0.7 0.41 9.7 0.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5520) BUD22 PF09073.10 EGO58944.1 - 2.8 7.2 28.9 6.8 5.9 28.9 1.6 1 0 0 1 1 1 0 BUD22 Lipase_GDSL_2 PF13472.6 EGO58945.1 - 9.3e-18 65.2 1.9 9.7e-17 61.9 1.9 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGO58945.1 - 2.6e-10 40.6 0.0 5.5e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 EGO58945.1 - 0.0002 20.7 0.0 0.00032 20.0 0.0 1.2 1 0 0 1 1 1 1 OSK domain Ion_trans PF00520.31 EGO58946.1 - 2.3e-09 36.8 22.0 6.5e-09 35.4 22.0 1.7 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EGO58946.1 - 8.7e-06 24.7 10.1 0.0079 14.9 3.8 2.2 1 1 1 2 2 2 2 Polycystin cation channel PNTB_4TM PF12769.7 EGO58946.1 - 0.00059 20.2 0.4 0.0016 18.9 0.4 1.7 1 0 0 1 1 1 1 4TM region of pyridine nucleotide transhydrogenase, mitoch Podoplanin PF05808.11 EGO58947.1 - 0.0079 16.3 9.0 0.016 15.3 9.0 1.5 1 0 0 1 1 1 1 Podoplanin DJ-1_PfpI PF01965.24 EGO58948.1 - 8.2e-15 55.0 0.0 4e-14 52.7 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EGO58948.1 - 4.1e-09 36.4 0.0 6.5e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 EGO58948.1 - 0.053 13.1 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Catalase_C PF18011.1 EGO58948.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 C-terminal domain found in long catalases MMS1_N PF10433.9 EGO58950.1 - 2.1e-126 422.4 0.6 3.3e-126 421.8 0.6 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGO58950.1 - 5.2e-70 236.3 0.0 3.4e-69 233.6 0.0 2.4 2 1 1 3 3 3 1 CPSF A subunit region Rieske PF00355.26 EGO58951.1 - 2.7e-11 43.2 0.0 4.7e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EGO58951.1 - 1.4e-09 38.3 0.9 4.1e-09 36.8 0.9 1.8 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region HET PF06985.11 EGO58953.1 - 1.4e-14 54.6 0.2 3.5e-14 53.4 0.2 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) R3H-assoc PF13902.6 EGO58954.1 - 2.4e-29 102.4 5.2 4e-29 101.7 0.2 2.2 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.22 EGO58954.1 - 0.0043 17.0 0.1 0.023 14.7 0.0 2.2 3 0 0 3 3 3 1 R3H domain MscS_TM PF12794.7 EGO58954.1 - 1.1 8.0 2.9 2 7.2 2.9 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 PQ-loop PF04193.14 EGO58955.1 - 5.1e-20 71.0 15.9 5e-11 42.2 2.5 3.1 3 0 0 3 3 3 2 PQ loop repeat DUF1345 PF07077.11 EGO58955.1 - 0.14 11.8 5.5 1.4 8.6 2.9 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1345) WD40 PF00400.32 EGO58956.1 - 0.027 15.4 1.1 64 4.7 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat ANAPC1 PF12859.7 EGO58957.1 - 0.22 12.1 1.4 0.73 10.4 1.4 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Ammonium_transp PF00909.21 EGO58958.1 - 1.4e-67 228.2 26.2 1.6e-67 227.9 26.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_3_1 PF05106.12 EGO58958.1 - 2.6 8.5 7.7 0.2 12.1 0.8 2.8 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) Fungal_trans_2 PF11951.8 EGO58959.1 - 2.9e-20 72.4 0.9 4.4e-20 71.9 0.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO58959.1 - 1.5e-06 28.2 9.2 2.8e-06 27.3 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_binding_2 PF13380.6 EGO58960.1 - 2.6e-27 95.6 0.0 3.2e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 EGO58960.1 - 0.12 13.1 0.0 0.19 12.5 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain Methyltransf_11 PF08241.12 EGO58961.1 - 2.2e-20 73.1 0.0 3.6e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO58961.1 - 6.5e-18 65.2 0.0 1e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO58961.1 - 3.4e-11 43.8 0.0 4.9e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO58961.1 - 1.1e-07 31.7 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO58961.1 - 1.9e-06 27.8 0.0 2.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO58961.1 - 3.4e-06 26.5 0.0 5.1e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 EGO58961.1 - 0.00082 18.6 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.11 EGO58961.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.14 EGO58961.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 EGO58961.1 - 0.023 14.6 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EGO58961.1 - 0.032 13.2 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_32 PF13679.6 EGO58961.1 - 0.078 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EGO58961.1 - 0.085 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase EF-hand_7 PF13499.6 EGO58962.1 - 3e-13 50.0 0.2 2.3e-08 34.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EGO58962.1 - 3.1e-12 46.6 0.0 9.2e-06 25.9 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 EGO58962.1 - 3.4e-10 39.0 0.5 0.0046 16.8 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EGO58962.1 - 5.3e-10 38.1 0.4 0.017 14.6 0.0 3.9 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGO58962.1 - 2.4e-08 33.7 0.2 3.2e-05 23.7 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain pair Peptidase_M3 PF01432.20 EGO58963.1 - 1.2e-113 380.9 0.2 1.1e-112 377.6 0.2 2.0 1 1 0 1 1 1 1 Peptidase family M3 APP_E2 PF12925.7 EGO58963.1 - 0.034 13.9 0.1 0.089 12.5 0.1 1.7 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein FIBP PF05427.11 EGO58963.1 - 0.044 13.1 0.1 0.077 12.3 0.1 1.3 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) Aa_trans PF01490.18 EGO58966.1 - 4.2e-84 282.6 30.6 4.8e-84 282.4 30.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Tetraspanin PF00335.20 EGO58966.1 - 0.2 11.4 0.0 0.2 11.4 0.0 3.2 2 1 1 3 3 3 0 Tetraspanin family BIR PF00653.21 EGO58968.1 - 3.3e-23 82.1 0.3 1e-21 77.3 0.0 2.6 2 1 0 2 2 2 1 Inhibitor of Apoptosis domain DUF4633 PF15464.6 EGO58968.1 - 0.03 14.5 0.6 0.03 14.5 0.6 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4633) LRR_9 PF14580.6 EGO58969.1 - 3.2e-53 179.8 0.2 5.3e-53 179.1 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGO58969.1 - 7.4e-08 32.6 8.9 0.00012 22.4 1.2 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGO58969.1 - 6.5e-07 29.0 0.6 6.5e-07 29.0 0.6 2.4 3 0 0 3 3 3 1 Leucine rich repeat DUF4349 PF14257.6 EGO58969.1 - 0.0016 17.9 2.1 0.0031 17.0 2.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) LRR_6 PF13516.6 EGO58969.1 - 0.0092 16.0 0.4 13 6.1 0.0 4.1 5 0 0 5 5 5 1 Leucine Rich repeat Nup88 PF10168.9 EGO58969.1 - 0.071 10.9 0.4 0.098 10.5 0.4 1.1 1 0 0 1 1 1 0 Nuclear pore component PspB PF06667.12 EGO58969.1 - 0.14 12.3 1.3 0.4 10.8 1.3 1.8 1 0 0 1 1 1 0 Phage shock protein B CBFD_NFYB_HMF PF00808.23 EGO58970.1 - 0.013 15.8 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Voltage_CLC PF00654.20 EGO58971.1 - 6.5e-89 298.6 28.3 6.5e-89 298.6 28.3 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EGO58971.1 - 2.7e-11 43.7 0.1 0.00015 22.1 0.0 2.6 2 0 0 2 2 2 2 CBS domain CDO_I PF05995.12 EGO58973.1 - 1.4e-44 151.4 0.0 2e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 EGO58973.1 - 0.0017 17.8 0.2 0.0033 16.9 0.2 1.5 1 1 0 1 1 1 1 PCO_ADO Pkinase PF00069.25 EGO58974.1 - 1.2e-23 83.9 0.0 1.7e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 EGO58974.1 - 2.7e-11 42.7 4.4 0.4 11.1 0.1 7.2 7 0 0 7 7 7 3 HEAT repeat WD40 PF00400.32 EGO58974.1 - 8.8e-09 35.9 14.3 8.6e-06 26.4 0.1 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 EGO58974.1 - 6.5e-06 25.6 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 EGO58974.1 - 4.9e-05 23.6 0.5 1.3 9.4 0.0 4.4 3 2 2 5 5 5 3 HEAT repeats DUF5549 PF17703.1 EGO58974.1 - 0.032 13.9 1.4 0.069 12.8 1.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Cnd1 PF12717.7 EGO58974.1 - 0.039 14.0 0.6 2 8.4 0.0 3.3 2 2 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 EGO58974.1 - 0.049 13.9 0.1 1.1 9.6 0.0 3.0 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain HEAT_EZ PF13513.6 EGO58974.1 - 0.061 13.9 0.2 0.061 13.9 0.2 3.6 6 0 0 6 6 6 0 HEAT-like repeat Kinase-like PF14531.6 EGO58974.1 - 0.079 12.3 0.0 0.16 11.2 0.0 1.5 1 1 0 1 1 1 0 Kinase-like PGBA_C PF15437.6 EGO58975.1 - 0.1 13.0 4.2 0.29 11.5 4.2 1.7 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Radical_SAM PF04055.21 EGO58977.1 - 3.4e-05 24.3 0.1 3.7e-05 24.2 0.1 1.2 1 1 0 1 1 1 1 Radical SAM superfamily SH3_9 PF14604.6 EGO58978.1 - 0.00021 21.1 0.1 0.00043 20.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGO58978.1 - 0.00046 19.7 0.1 0.001 18.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Adeno_E3_CR2 PF02439.15 EGO58978.1 - 0.0054 16.5 0.7 0.012 15.3 0.7 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Mucin15 PF15672.5 EGO58978.1 - 0.012 15.1 0.1 0.018 14.5 0.1 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Syndecan PF01034.20 EGO58978.1 - 0.026 14.4 0.3 0.053 13.4 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain Stevor PF17410.2 EGO58978.1 - 0.031 13.8 0.0 0.066 12.7 0.0 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame TMEM51 PF15345.6 EGO58978.1 - 0.073 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Mid2 PF04478.12 EGO58978.1 - 0.098 12.5 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.10 EGO58978.1 - 2.5 7.6 4.6 5 6.6 4.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3112 PF11309.8 EGO58979.1 - 5e-14 52.3 9.6 1.8e-11 44.0 0.7 2.5 1 1 0 2 2 2 2 Protein of unknown function (DUF3112) ECSCR PF15820.5 EGO58979.1 - 0.76 9.6 2.1 10 6.0 0.0 2.8 2 1 1 3 3 3 0 Endothelial cell-specific chemotaxis regulator Cation_efflux PF01545.21 EGO58979.1 - 1.7 8.3 14.0 4.2 7.0 0.4 2.4 1 1 1 2 2 2 0 Cation efflux family Bac_export_2 PF01312.19 EGO58979.1 - 7.9 5.6 8.1 15 4.7 8.1 1.4 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Metallophos PF00149.28 EGO58980.1 - 1e-37 130.6 0.4 1.7e-37 129.9 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGO58980.1 - 0.013 15.9 0.1 0.025 15.0 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Exo84_C PF16528.5 EGO58981.1 - 6.9e-70 235.0 0.2 6.9e-70 235.0 0.2 2.1 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EGO58981.1 - 2.1e-17 63.0 1.2 2.1e-17 63.0 1.2 2.9 3 0 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.11 EGO58981.1 - 7.6e-05 22.8 0.0 0.014 15.5 0.0 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 APG6_N PF17675.1 EGO58981.1 - 0.22 12.0 12.4 0.16 12.5 3.3 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 EGO58981.1 - 0.32 10.3 5.7 1.7 7.9 5.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Prominin PF05478.11 EGO58981.1 - 0.36 8.7 5.1 1.5 6.7 0.1 2.3 2 0 0 2 2 2 0 Prominin DUF4140 PF13600.6 EGO58981.1 - 3 8.3 6.5 4.9 7.7 0.1 3.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Uso1_p115_C PF04871.13 EGO58981.1 - 6.6 7.1 8.0 1.4 9.3 1.7 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region MAS20 PF02064.15 EGO58982.1 - 2.2e-43 147.4 1.4 2.8e-43 147.1 1.4 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor Nif11 PF07862.11 EGO58982.1 - 0.039 14.2 1.6 2.1 8.7 1.2 3.0 2 1 0 2 2 2 0 Nif11 domain Gluconate_2-dh3 PF13618.6 EGO58982.1 - 0.13 12.5 1.5 0.16 12.2 1.5 1.3 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Wyosine_form PF08608.12 EGO58983.1 - 1.8e-23 82.7 0.0 4.5e-23 81.4 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 EGO58983.1 - 2.6e-19 70.2 0.0 6.3e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 EGO58983.1 - 1.3e-08 35.2 0.0 1.7e-06 28.3 0.0 2.6 1 1 0 1 1 1 1 Flavodoxin EamA PF00892.20 EGO58984.1 - 0.015 15.5 13.1 0.14 12.3 13.1 2.0 1 1 0 1 1 1 0 EamA-like transporter family TFIIA_gamma_C PF02751.14 EGO58985.1 - 5.6e-24 84.0 1.0 9e-24 83.4 1.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 EGO58985.1 - 1.9e-22 79.0 0.2 2.6e-22 78.5 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain MoCF_biosynth PF00994.24 EGO58986.1 - 1.6e-54 183.5 1.5 9e-29 100.0 0.1 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 EGO58986.1 - 2.2e-40 138.0 3.6 3.6e-40 137.3 3.6 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 EGO58986.1 - 1e-14 54.5 0.0 2.7e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) ATP_bind_1 PF03029.17 EGO58987.1 - 2e-71 240.6 0.2 5e-71 239.3 0.1 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein WD40 PF00400.32 EGO58988.1 - 1.5e-17 63.6 0.2 7e-05 23.5 0.2 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO58988.1 - 0.00075 19.8 0.0 1.2 9.5 0.0 3.8 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HPS3_N PF14761.6 EGO58988.1 - 0.061 12.9 0.0 7.8 6.0 0.0 3.3 2 1 2 4 4 4 0 Hermansky-Pudlak syndrome 3 RRM_1 PF00076.22 EGO58990.1 - 5.5e-25 87.0 0.0 7.2e-12 44.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.20 EGO58991.1 - 4.5e-62 209.5 0.0 6.7e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGO58991.1 - 3.9e-34 117.9 0.8 8.4e-34 116.8 0.8 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EGO58991.1 - 8.4e-20 71.4 0.0 5.6e-19 68.8 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Shikimate_DH PF01488.20 EGO58991.1 - 0.041 14.0 0.2 0.085 12.9 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Flavodoxin_5 PF12724.7 EGO58991.1 - 0.078 13.2 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain MOR2-PAG1_N PF14222.6 EGO58992.1 - 1.5e-217 723.9 0.2 3.2e-217 722.9 0.1 1.6 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EGO58992.1 - 9.7e-95 317.2 0.1 4.3e-94 315.1 0.1 2.2 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EGO58992.1 - 4.3e-39 134.0 7.6 3.4e-18 64.8 0.1 3.7 2 1 1 3 3 3 3 Cell morphogenesis central region Zn_clus PF00172.18 EGO58993.1 - 2.1e-07 30.9 8.2 3.8e-07 30.1 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGO58993.1 - 0.0013 17.7 0.0 0.0032 16.3 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain TauD PF02668.16 EGO58994.1 - 1.9e-49 168.9 0.1 2.6e-49 168.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_125 PF06824.11 EGO58995.1 - 2e-167 557.3 0.0 2.5e-167 557.0 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Clr2 PF10383.9 EGO58996.1 - 6e-17 62.8 0.0 6e-17 62.8 0.0 2.8 2 1 0 2 2 1 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 EGO58996.1 - 5.6e-13 49.5 0.5 5.6e-13 49.5 0.5 2.2 2 1 0 2 2 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 DDHD PF02862.17 EGO58996.1 - 0.00033 20.9 4.3 0.00048 20.4 4.3 1.4 1 0 0 1 1 1 1 DDHD domain Otopetrin PF03189.13 EGO58996.1 - 0.012 14.4 1.6 0.015 14.2 1.6 1.1 1 0 0 1 1 1 0 Otopetrin AUX_IAA PF02309.16 EGO58996.1 - 0.022 14.6 4.2 0.033 14.0 4.2 1.2 1 0 0 1 1 1 0 AUX/IAA family Velvet PF11754.8 EGO58996.1 - 0.028 14.4 12.4 0.051 13.5 12.4 1.4 1 0 0 1 1 1 0 Velvet factor Presenilin PF01080.17 EGO58996.1 - 0.11 11.3 21.0 0.16 10.7 21.0 1.2 1 0 0 1 1 1 0 Presenilin PA26 PF04636.13 EGO58996.1 - 0.61 8.9 13.9 0.88 8.4 13.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FAM222A PF15258.6 EGO58996.1 - 0.67 9.0 37.1 1.8 7.6 36.8 1.7 2 0 0 2 2 2 0 Protein family of FAM222A Ndc1_Nup PF09531.10 EGO58996.1 - 0.82 8.3 12.7 1.1 7.9 12.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup VIT1 PF01988.19 EGO58996.1 - 2.4 8.0 6.3 4.3 7.2 6.3 1.4 1 0 0 1 1 1 0 VIT family Pex14_N PF04695.13 EGO58996.1 - 2.4 8.8 29.4 4.1 8.0 29.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hydin_ADK PF17213.3 EGO58996.1 - 2.6 8.3 18.8 4.3 7.6 18.8 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain V_ATPase_I PF01496.19 EGO58996.1 - 2.6 5.8 17.6 3.7 5.3 17.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ctr PF04145.15 EGO58996.1 - 3.7 8.2 7.8 6.7 7.3 7.8 1.4 1 0 0 1 1 1 0 Ctr copper transporter family LMBR1 PF04791.16 EGO58996.1 - 3.7 6.3 11.5 5.1 5.9 11.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Hid1 PF12722.7 EGO58996.1 - 3.8 5.5 18.9 4.9 5.1 18.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MCU PF04678.13 EGO58996.1 - 4.5 7.3 14.3 8.3 6.5 14.3 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Connexin PF00029.19 EGO58996.1 - 4.7 6.9 12.2 8.4 6.1 12.2 1.4 1 0 0 1 1 1 0 Connexin tRNA_synt_1c_R2 PF04557.15 EGO58996.1 - 4.8 8.2 16.6 13 6.8 16.6 1.7 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 ALMT PF11744.8 EGO58996.1 - 5.1 5.8 19.4 7.2 5.3 19.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.9 EGO58996.1 - 6.4 4.9 38.0 8.9 4.4 38.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PepSY_TM PF03929.16 EGO58996.1 - 8.1 6.0 7.8 13 5.3 7.8 1.4 1 0 0 1 1 1 0 PepSY-associated TM region Macoilin PF09726.9 EGO58996.1 - 9.7 4.6 20.9 13 4.2 20.9 1.1 1 0 0 1 1 1 0 Macoilin family PTPRCAP PF15713.5 EGO58996.1 - 9.9 6.4 23.0 23 5.2 23.0 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated adh_short PF00106.25 EGO58998.1 - 1.6e-22 80.0 0.0 8.2e-21 74.4 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO58998.1 - 3.7e-13 49.6 0.1 5.9e-12 45.6 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO58998.1 - 6.4e-06 26.2 0.1 1.7e-05 24.8 0.1 1.6 2 0 0 2 2 2 1 KR domain Corona_NS2A PF05213.12 EGO58998.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NS2A protein SUN PF03856.13 EGO59000.1 - 2.4e-77 259.7 10.6 3.1e-77 259.3 10.6 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Thiolase_N PF00108.23 EGO59002.1 - 5.4e-88 294.7 0.5 5.4e-88 294.7 0.5 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGO59002.1 - 1.1e-38 131.6 0.7 1.1e-38 131.6 0.7 2.0 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGO59002.1 - 1.3e-05 24.9 0.5 0.00041 20.0 0.3 2.6 1 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain UQ_con PF00179.26 EGO59003.1 - 3.9e-52 175.6 0.1 4.4e-52 175.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO59003.1 - 0.00052 19.7 0.0 0.00058 19.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGO59003.1 - 0.049 13.9 0.0 0.063 13.6 0.0 1.4 1 1 0 1 1 1 0 RWD domain Glyco_hydro_2_N PF02837.18 EGO59004.1 - 0.23 11.4 0.0 0.32 10.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Kinesin PF00225.23 EGO59005.1 - 3e-113 378.1 0.1 3e-113 378.1 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGO59005.1 - 7e-27 94.2 0.0 3.3e-26 92.0 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding HAP1_N PF04849.13 EGO59005.1 - 5.5 6.1 52.8 4.6 6.4 17.0 3.6 3 0 0 3 3 3 0 HAP1 N-terminal conserved region 4HBT PF03061.22 EGO59007.1 - 0.031 14.6 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily Asp PF00026.23 EGO59008.1 - 4.5e-08 32.9 2.3 9.6e-07 28.5 2.3 2.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Phage_stabilise PF11134.8 EGO59008.1 - 0.061 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Phage stabilisation protein Shisa PF13908.6 EGO59008.1 - 0.16 12.2 4.3 0.22 11.8 0.1 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator FAD_binding_1 PF00667.20 EGO59010.1 - 8.8e-28 97.4 0.0 2.7e-27 95.8 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGO59010.1 - 4.6e-12 46.3 0.0 1.3e-11 44.9 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 EGO59010.1 - 7.6e-11 42.6 0.0 1.4e-09 38.6 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain RRM_1 PF00076.22 EGO59011.1 - 2.3e-31 107.4 0.1 2.3e-15 56.2 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO59011.1 - 0.00012 22.1 0.0 0.09 12.9 0.0 2.7 2 2 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 EGO59011.1 - 0.00025 20.7 0.0 0.24 11.0 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EGO59011.1 - 0.019 15.2 0.0 7.4 6.8 0.0 3.2 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF4783 PF16022.5 EGO59011.1 - 0.049 13.8 0.0 0.77 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) DbpA PF03880.15 EGO59011.1 - 0.052 13.5 0.2 9.3 6.3 0.1 2.8 3 0 0 3 3 3 0 DbpA RNA binding domain Limkain-b1 PF11608.8 EGO59011.1 - 0.067 13.3 0.4 9.2 6.4 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 FXMRP1_C_core PF12235.8 EGO59011.1 - 0.9 10.2 19.2 0.24 12.1 14.9 2.1 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Pns11_12 PF17464.2 EGO59011.1 - 5.8 6.6 6.4 11 5.6 6.4 1.4 1 0 0 1 1 1 0 Non-structural protein 11 and 12 ArfGap PF01412.18 EGO59012.1 - 3e-33 114.4 0.2 5.1e-33 113.6 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ETF PF01012.21 EGO59013.1 - 6e-44 150.1 0.9 7.3e-44 149.8 0.9 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Trp_ring PF18669.1 EGO59013.1 - 0.079 13.1 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Trimeric autotransporter adhesin Trp ring domain GATase PF00117.28 EGO59014.1 - 9.1e-48 162.5 0.0 1.3e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EGO59014.1 - 2.2e-46 156.8 0.0 3.6e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 EGO59014.1 - 2.3e-05 24.3 0.2 0.0023 17.7 0.2 2.8 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EGO59014.1 - 0.026 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family SAP PF02037.27 EGO59015.1 - 1.9e-13 49.8 0.6 3.7e-13 48.9 0.6 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 EGO59015.1 - 0.12 12.1 0.6 0.29 10.9 0.6 1.6 1 1 0 1 1 1 0 HeH/LEM domain PBP1_TM PF14812.6 EGO59016.1 - 3.3 8.1 6.6 9.6 6.7 6.6 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GATA PF00320.27 EGO59017.1 - 7.2e-30 102.3 14.6 2.8e-15 55.6 2.8 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 EGO59017.1 - 1.6e-06 27.5 1.6 0.015 14.8 0.0 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 EGO59017.1 - 9.8e-06 25.6 1.3 0.057 13.5 0.1 2.7 2 0 0 2 2 2 2 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 EGO59017.1 - 0.00026 20.9 3.9 0.035 14.0 0.5 2.7 2 0 0 2 2 2 2 Putative transposase DNA-binding domain DZR PF12773.7 EGO59017.1 - 0.0014 18.6 8.7 0.65 10.1 0.2 3.1 2 1 0 2 2 2 2 Double zinc ribbon ArfGap PF01412.18 EGO59017.1 - 0.0019 18.2 3.8 0.46 10.6 0.2 2.6 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.12 EGO59017.1 - 0.0025 17.9 4.7 0.2 11.8 0.4 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RRN7 PF11781.8 EGO59017.1 - 0.03 14.0 0.5 0.03 14.0 0.5 3.0 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-5_eIF-2B PF01873.17 EGO59017.1 - 0.087 12.7 7.5 2.8 7.9 0.6 3.0 3 0 0 3 3 3 0 Domain found in IF2B/IF5 DUF2387 PF09526.10 EGO59017.1 - 0.13 12.5 0.5 6.2 7.1 0.1 2.6 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-ribbon_3 PF13248.6 EGO59017.1 - 0.23 10.9 9.1 11 5.6 0.1 4.2 4 0 0 4 4 4 0 zinc-ribbon domain CCDC-167 PF15188.6 EGO59017.1 - 0.58 10.5 2.7 1.4 9.3 2.7 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Jiv90 PF14901.6 EGO59017.1 - 0.93 9.7 2.7 2 8.6 0.2 2.3 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone Nudix_N_2 PF14803.6 EGO59017.1 - 2.4 8.1 9.7 18 5.4 0.1 3.4 3 0 0 3 3 3 0 Nudix N-terminal Rubredoxin_2 PF18073.1 EGO59017.1 - 4 7.2 10.3 13 5.6 0.2 4.4 4 0 0 4 4 4 0 Rubredoxin metal binding domain ADK_lid PF05191.14 EGO59017.1 - 5.3 7.1 6.7 3 7.9 0.3 3.2 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-Sec23_Sec24 PF04810.15 EGO59017.1 - 5.4 7.2 13.9 0.069 13.2 0.7 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger COPI_assoc PF08507.10 EGO59018.1 - 5.7e-34 117.0 6.2 6e-34 116.9 6.2 1.0 1 0 0 1 1 1 1 COPI associated protein TMEM72 PF16054.5 EGO59018.1 - 1.6 8.4 5.6 8.7 6.0 5.6 1.9 1 1 0 1 1 1 0 Transmembrane protein family 72 BCIP PF13862.6 EGO59019.1 - 7.1e-65 218.6 0.3 9.4e-65 218.3 0.3 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein WD40 PF00400.32 EGO59021.1 - 1.8e-31 107.7 8.5 3.2e-06 27.8 0.7 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO59021.1 - 1.2e-08 35.1 0.0 0.11 12.8 0.0 5.0 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO59021.1 - 4.3e-06 25.7 4.7 0.46 9.1 0.2 4.9 3 2 2 5 5 5 3 Nucleoporin Nup120/160 APG6_N PF17675.1 EGO59021.1 - 0.075 13.6 3.9 0.15 12.6 3.9 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc7 PF08317.11 EGO59021.1 - 0.076 11.9 2.9 0.12 11.2 2.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Aldo_ket_red PF00248.21 EGO59022.1 - 1.1e-68 231.6 0.0 1.3e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1279 PF06916.13 EGO59022.1 - 0.02 15.4 0.1 0.046 14.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) Roc PF08477.13 EGO59022.1 - 0.1 12.8 0.3 15 5.8 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RIO1 PF01163.22 EGO59023.1 - 6.3e-41 140.0 0.5 1.8e-28 99.4 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 EGO59023.1 - 1e-31 109.0 0.1 2.9e-31 107.5 0.0 1.8 2 0 0 2 2 1 1 Rio2, N-terminal APH PF01636.23 EGO59023.1 - 4.8e-08 33.2 0.2 0.00021 21.3 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGO59023.1 - 2.2e-05 23.9 0.1 0.042 13.2 0.0 2.4 1 1 1 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Alpha-2-MRAP_C PF06401.11 EGO59023.1 - 0.0064 16.5 2.0 0.0064 16.5 2.0 1.6 2 0 0 2 2 2 1 Alpha-2-macroglobulin RAP, C-terminal domain RNA_pol_3_Rpc31 PF11705.8 EGO59023.1 - 0.12 12.6 16.3 0.29 11.4 16.3 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF3449 PF11931.8 EGO59023.1 - 0.22 11.3 4.2 0.43 10.4 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF4611 PF15387.6 EGO59023.1 - 0.26 11.5 12.4 0.64 10.3 12.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Pes-10 PF07149.11 EGO59023.1 - 0.29 10.1 10.5 0.43 9.6 10.5 1.2 1 0 0 1 1 1 0 Pes-10 Nop53 PF07767.11 EGO59023.1 - 0.39 10.1 12.0 0.63 9.4 12.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Drc1-Sld2 PF11719.8 EGO59023.1 - 0.41 10.1 5.5 0.51 9.8 5.5 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein RXT2_N PF08595.11 EGO59023.1 - 0.5 10.4 9.5 0.98 9.4 9.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal RPN2_C PF18004.1 EGO59023.1 - 0.54 10.2 6.9 0.98 9.3 6.9 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain BUD22 PF09073.10 EGO59023.1 - 0.69 9.2 11.6 0.76 9.0 10.0 1.7 2 0 0 2 2 2 0 BUD22 DNA_pol_phi PF04931.13 EGO59023.1 - 0.75 7.8 21.0 1.3 7.0 21.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 EGO59023.1 - 1.5 7.9 18.9 2.6 7.1 18.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.12 EGO59023.1 - 1.5 8.5 17.6 2.8 7.6 17.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RRN3 PF05327.11 EGO59023.1 - 2.9 6.3 11.9 4.2 5.8 11.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EGO59023.1 - 3.6 5.8 12.1 6.7 4.9 12.1 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EGO59023.1 - 3.7 6.8 15.3 5.5 6.2 15.3 1.2 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.12 EGO59023.1 - 4.7 6.5 16.2 7.2 5.9 16.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Vfa1 PF08432.10 EGO59023.1 - 5 7.4 9.2 8.8 6.6 9.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 EGO59023.1 - 8.7 4.4 17.7 12 3.9 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family RPN1_RPN2_N PF17781.1 EGO59024.1 - 1.2e-117 392.7 2.8 2.2e-117 391.9 2.8 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EGO59024.1 - 2.3e-29 101.2 0.0 4.1e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EGO59024.1 - 1.1e-24 85.5 14.2 3.9e-05 23.9 0.0 9.0 8 0 0 8 8 8 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGO59024.1 - 2.2e-07 31.2 1.4 0.025 14.9 0.0 5.2 5 2 2 7 7 7 2 HEAT repeats MatE PF01554.18 EGO59025.1 - 1.5e-61 206.7 30.9 1.4e-33 115.8 12.3 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EGO59025.1 - 0.00018 21.6 10.3 0.00018 21.6 10.3 4.1 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain NUDIX PF00293.28 EGO59026.1 - 7.7e-27 93.9 0.0 1.1e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_9 PF13527.7 EGO59027.1 - 1.3e-06 28.5 0.0 2.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO59027.1 - 3.9e-06 27.2 0.0 7.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO59027.1 - 4.2e-06 27.0 0.0 8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO59027.1 - 3.2e-05 23.9 0.0 5.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGO59027.1 - 0.012 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 EGO59027.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein RPA_C PF08784.11 EGO59028.1 - 2.3e-32 111.7 1.4 2.6e-32 111.6 0.2 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EGO59028.1 - 1.2e-06 28.4 0.2 2.2e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Keratin_2_head PF16208.5 EGO59028.1 - 0.59 10.3 27.9 0.25 11.5 13.1 2.3 2 0 0 2 2 2 0 Keratin type II head DUF202 PF02656.15 EGO59029.1 - 1.6e-16 60.4 0.1 2.3e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.12 EGO59029.1 - 0.033 14.3 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV SDA1 PF05285.12 EGO59031.1 - 0.00072 19.1 14.7 0.0012 18.4 14.7 1.3 1 0 0 1 1 1 1 SDA1 Arm PF00514.23 EGO59031.1 - 0.0064 16.5 0.1 3.7 7.7 0.0 3.1 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGO59031.1 - 0.038 14.3 0.0 1.3 9.5 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat Nop14 PF04147.12 EGO59031.1 - 0.15 10.3 20.8 0.27 9.4 20.8 1.4 1 0 0 1 1 1 0 Nop14-like family PBP_sp32 PF07222.12 EGO59031.1 - 2.8 7.3 5.6 42 3.5 0.0 2.3 2 0 0 2 2 2 0 Proacrosin binding protein sp32 DNA_pol_phi PF04931.13 EGO59031.1 - 3.2 5.8 35.0 7.3 4.6 35.0 1.5 1 0 0 1 1 1 0 DNA polymerase phi CNDH2_C PF16858.5 EGO59031.1 - 3.7 7.3 12.8 35 4.1 0.0 3.1 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Astro_capsid_p PF12226.8 EGO59031.1 - 6.6 5.8 24.6 13 4.8 24.6 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DnaJ PF00226.31 EGO59032.1 - 3.9e-11 42.9 0.4 1.3e-10 41.2 0.4 2.0 1 0 0 1 1 1 1 DnaJ domain T4BSS_DotH_IcmK PF12293.8 EGO59032.1 - 0.16 11.2 2.0 1 8.5 1.3 2.6 1 1 0 1 1 1 0 Putative outer membrane core complex of type IVb secretion DEAD PF00270.29 EGO59033.1 - 1.2e-47 162.0 0.0 5.7e-47 159.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO59033.1 - 1.5e-23 83.3 0.0 5.6e-23 81.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EGO59033.1 - 2.7e-22 78.8 2.8 8.5e-22 77.2 2.8 1.9 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Na_Ca_ex PF01699.24 EGO59034.1 - 4e-38 130.7 27.8 5.5e-21 75.1 12.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Claudin_2 PF13903.6 EGO59034.1 - 0.11 12.3 3.4 0.49 10.1 0.0 2.6 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction IML1 PF12257.8 EGO59035.1 - 6.6e-117 389.7 0.0 9.4e-117 389.2 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EGO59035.1 - 3.4e-26 91.1 0.1 8.9e-26 89.8 0.1 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Cation_efflux PF01545.21 EGO59036.1 - 4.9e-13 49.3 2.7 9.3e-13 48.4 2.7 1.5 1 0 0 1 1 1 1 Cation efflux family DUF4964 PF16334.5 EGO59037.1 - 0.0083 15.7 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) AUDH_Cupin PF18637.1 EGO59037.1 - 0.065 13.2 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain FNIP_N PF14636.6 EGO59039.1 - 4.4e-32 112.2 5.1 5.3e-28 98.9 1.9 5.9 4 3 2 6 6 6 2 Folliculin-interacting protein N-terminus FNIP_C PF14638.6 EGO59039.1 - 0.035 13.7 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus IBR PF01485.21 EGO59040.1 - 0.66 10.2 6.2 2 8.7 0.1 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Zn_clus PF00172.18 EGO59041.1 - 4.6e-09 36.3 7.9 4.6e-09 36.3 7.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactonase PF10282.9 EGO59043.1 - 1.5e-86 290.8 0.0 1.9e-86 290.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SR-25 PF10500.9 EGO59045.1 - 0.0034 17.0 3.8 0.0034 17.0 3.8 3.2 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Fungal_KA1 PF16797.5 EGO59045.1 - 0.055 13.2 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Fungal kinase associated-1 domain PseudoU_synth_1 PF01416.20 EGO59045.1 - 0.083 13.4 0.0 0.77 10.2 0.0 2.6 1 1 0 1 1 1 0 tRNA pseudouridine synthase Solute_trans_a PF03619.16 EGO59046.1 - 3.9e-101 338.0 7.3 4.6e-101 337.8 7.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha GTP_EFTU PF00009.27 EGO59047.1 - 5e-67 225.2 0.2 7.1e-67 224.7 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGO59047.1 - 6.7e-33 113.0 0.0 2.1e-32 111.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EGO59047.1 - 5.6e-22 77.6 0.0 1.8e-21 76.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGO59047.1 - 1e-12 48.3 0.0 3.3e-12 46.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGO59047.1 - 2.5e-12 46.7 0.0 7e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EGO59047.1 - 0.0003 20.8 0.2 0.00068 19.7 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PWI PF01480.17 EGO59048.1 - 3e-08 33.8 0.0 6.6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 EGO59048.1 - 4e-07 29.8 0.9 2e-06 27.5 0.1 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGO59048.1 - 3.5e-05 23.7 0.0 0.00076 19.4 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 EGO59048.1 - 8.8e-05 22.3 4.2 0.00016 21.5 4.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGO59048.1 - 0.00043 20.2 2.5 0.0009 19.2 2.5 1.6 1 0 0 1 1 1 1 Zinc finger domain PHM7_cyt PF14703.6 EGO59048.1 - 0.002 18.4 1.4 0.2 11.9 0.0 2.5 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter DUF4523 PF15023.6 EGO59048.1 - 0.17 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Borrelia_P83 PF05262.11 EGO59048.1 - 0.26 9.7 3.7 0.36 9.3 3.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Tex_N PF09371.10 EGO59048.1 - 0.67 9.6 6.8 0.68 9.6 5.5 1.6 2 0 0 2 2 2 0 Tex-like protein N-terminal domain Mgr1 PF08602.10 EGO59048.1 - 1.3 7.8 3.1 6.4 5.5 0.0 2.1 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit DUF4407 PF14362.6 EGO59048.1 - 1.8 7.8 7.0 2.7 7.3 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec5 PF15469.6 EGO59049.1 - 3.4e-35 121.6 0.0 9.4e-35 120.1 0.0 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 EGO59049.1 - 6.3e-05 23.0 0.9 0.00096 19.2 0.1 3.0 2 0 0 2 2 2 1 Vps51/Vps67 DUF2267 PF10025.9 EGO59049.1 - 0.037 14.3 0.5 0.35 11.2 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Iso_dh PF00180.20 EGO59050.1 - 2.5e-99 332.7 0.0 2.8e-99 332.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PrgH PF09480.10 EGO59051.1 - 0.012 15.0 0.2 0.012 15.0 0.2 1.0 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) SR-25 PF10500.9 EGO59051.1 - 0.034 13.8 7.9 0.032 13.8 7.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BSP PF04450.12 EGO59054.1 - 7.6e-77 257.8 0.0 9.5e-77 257.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria CLASP_N PF12348.8 EGO59055.1 - 5.7e-137 454.6 4.8 3.1e-92 308.3 0.2 3.1 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 EGO59055.1 - 1.2e-05 25.1 1.1 4.8 7.7 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 EGO59055.1 - 0.00078 19.5 0.4 1.6 8.8 0.0 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGO59055.1 - 0.0012 19.4 0.0 2.2 9.0 0.0 3.7 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region DUF3361 PF11841.8 EGO59055.1 - 0.0089 16.0 0.1 2.9 7.8 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) DUF4704 PF15787.5 EGO59055.1 - 0.082 12.1 0.1 10 5.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) Adaptin_N PF01602.20 EGO59055.1 - 0.092 11.3 0.0 2.6 6.5 0.0 3.0 2 1 0 3 3 3 0 Adaptin N terminal region RTP1_C1 PF10363.9 EGO59055.1 - 0.2 11.8 0.8 12 6.1 0.0 3.6 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 zf-BED PF02892.15 EGO59056.1 - 0.16 12.1 1.7 0.19 11.8 0.3 1.9 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.6 EGO59056.1 - 3.1 7.9 5.3 2.2 8.4 1.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF676 PF05057.14 EGO59057.1 - 1.2e-45 155.7 0.1 1.8e-29 102.9 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) DUF915 PF06028.11 EGO59057.1 - 0.018 14.4 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 EGO59057.1 - 0.1 12.5 0.3 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_2 PF02230.16 EGO59057.1 - 0.18 11.6 0.1 4.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2201_N PF13203.6 EGO59057.1 - 1.1 8.8 6.0 0.12 11.9 1.1 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain MTHFR PF02219.17 EGO59058.1 - 2.9e-114 381.2 0.0 5.3e-114 380.4 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase RhoGAP PF00620.27 EGO59059.1 - 4.6e-48 162.9 2.0 9.4e-48 161.9 0.2 2.3 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 EGO59059.1 - 9.1e-14 51.4 18.6 3.9e-09 36.6 2.2 2.4 2 0 0 2 2 2 2 LIM domain zf-C3HC4_3 PF13920.6 EGO59059.1 - 0.86 9.5 16.9 0.11 12.4 5.1 3.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) rRNA_processing PF08524.11 EGO59060.1 - 0.0045 17.0 32.5 0.047 13.7 11.1 2.3 1 1 1 2 2 2 1 rRNA processing Presenilin PF01080.17 EGO59060.1 - 1.7 7.4 11.3 2.4 6.8 11.3 1.2 1 0 0 1 1 1 0 Presenilin DUF4210 PF13915.6 EGO59061.1 - 2.4e-32 111.3 0.1 5e-32 110.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 EGO59061.1 - 1.1e-24 86.4 0.7 3.3e-24 84.8 0.7 1.9 1 0 0 1 1 1 1 Chromosome segregation during meiosis Npa1 PF11707.8 EGO59062.1 - 8.7e-102 341.0 0.4 2.7e-101 339.3 0.0 2.1 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EGO59062.1 - 4.8e-60 202.6 0.1 1.8e-59 200.7 0.1 2.0 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Creb_binding PF09030.10 EGO59062.1 - 0.0032 18.1 0.0 0.038 14.7 0.0 2.8 2 0 0 2 2 2 1 Creb binding PPR_long PF17177.4 EGO59064.1 - 9.4e-09 34.9 0.1 0.0058 16.0 0.0 2.9 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 EGO59064.1 - 2.4e-07 30.8 0.0 0.42 10.8 0.0 5.6 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.20 EGO59064.1 - 3.4e-06 26.9 0.4 1.4 9.3 0.0 5.0 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 EGO59064.1 - 3e-05 24.0 0.0 0.0081 16.2 0.0 3.6 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGO59064.1 - 0.0091 15.7 3.6 23 4.8 0.0 5.3 7 0 0 7 7 7 1 PPR repeat Malate_synthase PF01274.22 EGO59064.1 - 0.071 11.4 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Malate synthase LSM PF01423.22 EGO59065.1 - 1.9e-16 59.5 0.1 2.5e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGO59065.1 - 0.08 13.1 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain GRP PF07172.11 EGO59065.1 - 0.87 10.3 22.1 1.1 10.0 22.1 1.3 1 0 0 1 1 1 0 Glycine rich protein family BAR_2 PF10455.9 EGO59066.1 - 2.7e-59 200.7 0.5 3.8e-59 200.2 0.5 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EGO59066.1 - 9.3e-22 77.8 6.6 3.5e-20 72.7 6.6 2.1 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EGO59066.1 - 0.00014 21.7 2.0 0.00053 19.8 0.2 2.2 2 0 0 2 2 2 1 BAR domain of APPL family GCP_C_terminal PF04130.13 EGO59066.1 - 0.33 10.4 1.6 0.7 9.3 1.6 1.8 1 1 0 1 1 1 0 Gamma tubulin complex component C-terminal NAT PF04768.13 EGO59067.1 - 1.1e-50 171.6 0.0 5e-50 169.5 0.0 1.9 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase NAD_binding_2 PF03446.15 EGO59068.1 - 2.6e-30 105.7 0.1 4e-30 105.1 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGO59068.1 - 3.1e-08 33.9 0.0 5.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EGO59068.1 - 1.5e-05 25.4 0.2 4.6e-05 23.9 0.1 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EGO59068.1 - 2e-05 24.6 0.1 4.8e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 EGO59068.1 - 0.029 13.9 0.2 0.061 12.9 0.2 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 EGO59068.1 - 0.048 13.9 0.3 0.11 12.7 0.1 1.7 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Arv1 PF04161.13 EGO59069.1 - 8.2e-57 192.8 6.7 2.9e-32 112.6 1.0 2.2 1 1 1 2 2 2 2 Arv1-like family LysM PF01476.20 EGO59069.1 - 0.0011 18.9 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 LysM domain SMC_N PF02463.19 EGO59070.1 - 4.7e-70 235.5 8.8 1.1e-38 132.8 0.2 2.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGO59070.1 - 4.4e-23 81.8 0.9 6.6e-22 78.0 0.1 3.3 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EGO59070.1 - 3.1e-11 43.7 0.9 0.00016 21.6 0.2 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGO59070.1 - 2.1e-09 38.2 24.9 2.1e-09 38.2 24.9 7.1 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.6 EGO59070.1 - 0.00014 21.6 0.1 0.00032 20.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3046 PF11248.8 EGO59070.1 - 0.11 12.8 0.0 0.41 11.0 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) ABC_tran PF00005.27 EGO59070.1 - 0.12 12.9 0.0 0.12 12.9 0.0 6.1 2 2 1 4 4 4 0 ABC transporter PASTA PF03793.19 EGO59070.1 - 1.6 8.6 7.9 16 5.4 0.0 4.6 5 0 0 5 5 5 0 PASTA domain Fungal_trans_2 PF11951.8 EGO59073.1 - 1e-14 54.2 1.9 1.4e-14 53.8 0.7 1.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO59073.1 - 3.9e-08 33.3 10.2 7.3e-08 32.4 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Csm4_C PF17953.1 EGO59073.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain Mob1_phocein PF03637.17 EGO59074.1 - 4.4e-21 75.6 2.4 7.2e-21 74.9 2.4 1.2 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 EGO59074.1 - 0.21 11.9 3.7 0.49 10.7 3.7 1.6 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases cobW PF02492.19 EGO59075.1 - 7.8e-48 162.4 0.4 1e-47 162.0 0.4 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EGO59075.1 - 3.5e-05 23.8 0.2 0.28 11.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase CobW_C PF07683.14 EGO59075.1 - 0.00048 20.0 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_23 PF13476.6 EGO59075.1 - 0.012 16.1 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGO59075.1 - 0.013 15.6 0.0 0.024 14.7 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EGO59075.1 - 0.015 15.1 0.2 0.83 9.4 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EGO59075.1 - 0.016 15.7 0.1 0.46 11.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGO59075.1 - 0.02 15.3 0.0 0.053 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EGO59075.1 - 0.021 14.1 0.4 4.6 6.4 0.1 2.2 2 0 0 2 2 2 0 Septin Zeta_toxin PF06414.12 EGO59075.1 - 0.025 13.8 0.0 0.25 10.6 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin MeaB PF03308.16 EGO59075.1 - 0.03 13.3 1.5 2.8 6.8 0.1 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 EGO59075.1 - 0.039 13.5 2.4 0.78 9.2 2.4 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_30 PF13604.6 EGO59075.1 - 0.048 13.4 0.3 0.44 10.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGO59075.1 - 0.06 13.6 0.2 0.39 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGO59075.1 - 0.073 12.8 0.2 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain TsaE PF02367.17 EGO59075.1 - 0.084 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 EGO59075.1 - 0.097 11.7 0.1 0.21 10.6 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 EGO59075.1 - 0.17 11.9 0.1 0.76 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain NOT2_3_5 PF04153.18 EGO59076.1 - 3.4e-29 101.6 0.6 5e-29 101.0 0.6 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Herpes_LMP2 PF07415.11 EGO59076.1 - 7.6 5.2 5.3 11 4.6 5.3 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein YhfH PF14149.6 EGO59077.1 - 0.058 13.4 0.1 0.087 12.8 0.1 1.3 1 0 0 1 1 1 0 YhfH-like protein CUE PF02845.16 EGO59078.1 - 9.2e-13 47.6 0.0 1.3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain TMEM171 PF15471.6 EGO59078.1 - 0.036 13.0 0.2 0.045 12.7 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF737 PF05300.11 EGO59078.1 - 1.1 9.5 5.3 11 6.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) DEAD PF00270.29 EGO59080.1 - 2e-44 151.5 0.1 4.4e-44 150.3 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO59080.1 - 1.4e-21 76.9 0.0 1.4e-20 73.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO59080.1 - 1.7e-05 24.9 0.0 3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGO59080.1 - 0.0067 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Fungal_trans PF04082.18 EGO59081.1 - 1.1e-24 87.0 0.0 1.1e-24 87.0 0.0 2.3 2 1 0 2 2 1 1 Fungal specific transcription factor domain Baculo_PP31 PF05311.11 EGO59081.1 - 0.00047 19.7 2.3 0.00081 19.0 2.3 1.4 1 0 0 1 1 1 1 Baculovirus 33KDa late protein (PP31) DUF1387 PF07139.11 EGO59081.1 - 0.045 13.5 17.1 0.11 12.2 17.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SID-1_RNA_chan PF13965.6 EGO59081.1 - 0.062 11.7 0.9 0.084 11.3 0.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.12 EGO59081.1 - 0.13 12.0 15.1 0.29 10.9 15.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Macoilin PF09726.9 EGO59081.1 - 0.14 10.7 11.5 0.2 10.2 11.5 1.2 1 0 0 1 1 1 0 Macoilin family Borrelia_P83 PF05262.11 EGO59081.1 - 0.15 10.5 10.8 0.23 9.9 10.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein GREB1 PF15782.5 EGO59081.1 - 0.27 8.3 20.9 0.39 7.8 20.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 EGO59081.1 - 0.31 9.1 14.5 0.44 8.6 14.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MMU163 PF17119.5 EGO59081.1 - 0.38 9.9 8.3 13 4.8 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis AAA_23 PF13476.6 EGO59081.1 - 0.85 10.1 15.8 2.4 8.6 15.8 1.7 1 0 0 1 1 1 0 AAA domain DUF913 PF06025.12 EGO59081.1 - 1.3 7.9 8.8 2.1 7.2 8.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) HSNSD PF12062.8 EGO59081.1 - 2 7.1 8.4 2.9 6.5 8.4 1.1 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase FAM76 PF16046.5 EGO59081.1 - 2.5 7.4 20.9 5.5 6.3 20.9 1.5 1 0 0 1 1 1 0 FAM76 protein Tim54 PF11711.8 EGO59081.1 - 3.4 6.4 17.5 7.1 5.3 17.5 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 EGO59081.1 - 3.4 7.8 14.0 8.6 6.5 14.0 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal LMBR1 PF04791.16 EGO59081.1 - 4.1 6.2 6.4 6.3 5.6 6.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein GIDA_assoc PF13932.6 EGO59081.1 - 5.9 7.0 15.0 1.1e+02 2.9 14.0 2.3 2 0 0 2 2 2 0 GidA associated domain Peptidase_U57 PF05582.12 EGO59081.1 - 7.5 5.7 13.4 14 4.9 13.4 1.3 1 0 0 1 1 1 0 YabG peptidase U57 TOM13 PF08219.11 EGO59082.1 - 0.027 14.4 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein TOM13 MFS_1 PF07690.16 EGO59083.1 - 3.7e-33 114.9 17.4 3.7e-33 114.9 17.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO59083.1 - 2.8e-07 29.8 5.0 2.8e-07 29.8 5.0 2.6 2 2 0 2 2 2 1 Sugar (and other) transporter Ccdc124 PF06244.12 EGO59086.1 - 8.6e-31 107.2 6.7 8.6e-31 107.2 6.7 2.2 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 124 /Oxs1 Hc1 PF07432.13 EGO59086.1 - 5.5 7.4 23.6 5.5 7.4 3.3 2.5 2 0 0 2 2 2 0 Histone H1-like protein Hc1 UQ_con PF00179.26 EGO59087.1 - 1.3e-11 44.3 0.0 2.7e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme 2OG-FeII_Oxy_2 PF13532.6 EGO59089.1 - 2.2e-34 119.4 0.0 2.9e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 EGO59089.1 - 4e-10 39.6 3.9 6.9e-10 38.9 3.9 1.4 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.16 EGO59089.1 - 0.00013 21.6 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 CUE domain WD40 PF00400.32 EGO59090.1 - 1.8e-13 50.7 13.9 0.0054 17.5 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO59090.1 - 0.018 15.3 0.0 0.83 10.0 0.0 3.2 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain MinE PF03776.14 EGO59091.1 - 0.18 11.8 0.1 0.33 11.0 0.1 1.3 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE Hamartin PF04388.12 EGO59093.1 - 9.3e-23 80.8 0.2 9.3e-23 80.8 0.2 4.1 2 2 2 4 4 4 2 Hamartin protein Fungal_TACC PF12709.7 EGO59093.1 - 0.023 15.2 7.9 0.67 10.4 0.4 3.5 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins BLOC1_2 PF10046.9 EGO59093.1 - 3.3 8.1 15.5 0.36 11.2 1.7 3.9 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 EGO59093.1 - 9.2 5.0 33.5 0.41 9.5 15.8 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DJ-1_PfpI PF01965.24 EGO59094.1 - 2.4e-12 46.9 0.0 4.7e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EGO59094.1 - 0.02 14.6 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like Ribosomal_L23 PF00276.20 EGO59095.1 - 6.1e-10 39.3 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 Mito_carr PF00153.27 EGO59096.1 - 6.1e-63 208.8 2.1 4.6e-23 81.0 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGO59096.1 - 0.1 11.7 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Sugar_tr PF00083.24 EGO59097.1 - 7.6e-49 166.8 17.7 9.4e-49 166.5 17.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO59097.1 - 2.3e-19 69.5 24.0 3.5e-19 69.0 24.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF383 PF04063.14 EGO59098.1 - 7.3e-66 221.5 0.1 3e-65 219.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EGO59098.1 - 1.6e-22 79.1 0.5 5e-22 77.5 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Adaptin_N PF01602.20 EGO59098.1 - 0.055 12.0 0.0 0.12 10.9 0.0 1.4 1 0 0 1 1 1 0 Adaptin N terminal region Bystin PF05291.11 EGO59099.1 - 3.1e-120 400.9 0.0 4.2e-120 400.5 0.0 1.1 1 0 0 1 1 1 1 Bystin Astro_capsid_p PF12226.8 EGO59099.1 - 6.4 5.8 10.2 10 5.2 10.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC73_C PF05179.14 EGO59100.1 - 2.5e-53 180.0 0.0 3.8e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal RGS PF00615.19 EGO59103.1 - 2.3e-36 124.6 0.9 2.2e-35 121.5 0.1 2.7 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.21 EGO59103.1 - 1.2e-25 89.3 0.1 1.5e-21 76.2 0.1 3.5 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) NMT PF01233.19 EGO59103.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain DUF3439 PF11921.8 EGO59104.1 - 0.21 11.6 9.8 1.9 8.5 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mito_fiss_reg PF05308.11 EGO59104.1 - 2.1 8.4 12.9 0.063 13.4 4.0 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator ORC4_C PF14629.6 EGO59105.1 - 4.6e-73 245.2 0.0 9.5e-73 244.2 0.0 1.6 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus PHD PF00628.29 EGO59105.1 - 2.8e-12 46.3 5.5 4.9e-12 45.5 5.5 1.4 1 0 0 1 1 1 1 PHD-finger AAA_16 PF13191.6 EGO59105.1 - 3.2e-12 47.2 0.1 1e-11 45.5 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain PHD_2 PF13831.6 EGO59105.1 - 2e-11 43.2 1.7 4.3e-11 42.2 1.7 1.6 1 0 0 1 1 1 1 PHD-finger AAA PF00004.29 EGO59105.1 - 1.1e-07 32.3 0.0 3e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EGO59105.1 - 6.4e-07 29.4 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EGO59105.1 - 2.9e-05 24.4 0.0 7.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EGO59105.1 - 0.00013 21.4 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain C1_1 PF00130.22 EGO59105.1 - 0.00027 20.8 0.8 0.00068 19.5 0.8 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) NB-ARC PF00931.22 EGO59105.1 - 0.00039 19.7 0.2 0.00073 18.8 0.2 1.3 1 0 0 1 1 1 1 NB-ARC domain SMC_N PF02463.19 EGO59105.1 - 0.002 17.6 0.0 0.0041 16.6 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ATPase_2 PF01637.18 EGO59105.1 - 0.0025 17.8 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 EGO59105.1 - 0.0033 16.6 0.0 0.0055 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 EGO59105.1 - 0.0047 16.7 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGO59105.1 - 0.0049 16.6 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.6 EGO59105.1 - 0.0061 16.6 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGO59105.1 - 0.01 16.2 0.1 0.022 15.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain zf-PHD-like PF15446.6 EGO59105.1 - 0.011 15.4 4.2 0.037 13.6 4.2 2.0 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain TniB PF05621.11 EGO59105.1 - 0.015 14.7 0.1 0.82 9.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Prok-RING_1 PF14446.6 EGO59105.1 - 0.02 14.8 5.8 0.038 13.9 5.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FtsK_SpoIIIE PF01580.18 EGO59105.1 - 0.024 14.0 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 EGO59105.1 - 0.027 15.0 0.0 0.077 13.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 EGO59105.1 - 0.034 13.9 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EGO59105.1 - 0.036 13.6 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FYVE_2 PF02318.16 EGO59105.1 - 0.046 13.9 2.4 0.1 12.8 2.4 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger ORC2 PF04084.14 EGO59105.1 - 0.056 12.4 0.7 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Origin recognition complex subunit 2 Roc PF08477.13 EGO59105.1 - 0.056 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EGO59105.1 - 0.062 13.5 0.1 0.21 11.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 EGO59105.1 - 0.067 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TrwB_AAD_bind PF10412.9 EGO59105.1 - 0.088 11.7 0.1 0.19 10.6 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 EGO59105.1 - 0.092 13.3 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EGO59105.1 - 0.094 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Septin RNA_helicase PF00910.22 EGO59105.1 - 0.13 12.7 0.0 0.44 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Pes-10 PF07149.11 EGO59105.1 - 0.16 11.0 5.9 0.3 10.1 5.9 1.4 1 0 0 1 1 1 0 Pes-10 GTP_EFTU PF00009.27 EGO59105.1 - 0.2 11.2 0.8 0.56 9.7 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PHF5 PF03660.14 EGO59105.1 - 0.21 11.8 4.1 0.41 10.9 4.1 1.4 1 0 0 1 1 1 0 PHF5-like protein Zf_RING PF16744.5 EGO59105.1 - 4.8 7.4 5.5 1.1 9.5 1.7 1.8 2 0 0 2 2 1 0 KIAA1045 RING finger RSN1_7TM PF02714.15 EGO59106.1 - 7.2e-86 287.9 26.0 2e-85 286.4 26.0 1.8 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGO59106.1 - 2.6e-42 144.3 0.1 2.6e-42 144.3 0.1 3.5 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGO59106.1 - 1.8e-26 93.5 4.1 3.6e-15 56.6 0.3 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EGO59106.1 - 1.7e-16 60.1 0.0 4.7e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter FAD_binding_3 PF01494.19 EGO59107.1 - 3.6e-09 36.3 0.1 3e-08 33.3 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EGO59107.1 - 1e-05 24.8 0.0 1.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 EGO59107.1 - 0.016 15.4 0.0 0.049 13.9 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain CYSTM PF12734.7 EGO59108.1 - 2.1e-08 34.3 8.8 2.1e-08 34.3 8.8 2.7 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance RibD_C PF01872.17 EGO59109.1 - 6.3e-31 107.8 0.0 8.4e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain Sec1 PF00995.23 EGO59110.1 - 7e-116 388.7 0.0 8.1e-116 388.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family GrpE PF01025.19 EGO59110.1 - 0.37 10.4 2.7 0.81 9.3 2.4 1.8 1 1 0 1 1 1 0 GrpE Phage_pRha PF09669.10 EGO59110.1 - 3.2 8.4 4.8 5.7 7.6 0.7 2.9 2 1 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Transp_cyt_pur PF02133.15 EGO59111.1 - 4.6e-21 75.1 35.4 7.1e-20 71.2 35.4 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NMT PF01233.19 EGO59111.1 - 0.0019 18.0 0.2 0.9 9.4 0.0 2.3 1 1 1 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain DUF4996 PF16387.5 EGO59111.1 - 0.029 14.8 0.1 0.052 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function Mlh1_C PF16413.5 EGO59112.1 - 8e-101 336.9 0.0 2.6e-100 335.3 0.0 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EGO59112.1 - 7.7e-34 115.9 0.0 2.8e-33 114.1 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EGO59112.1 - 1.1e-11 44.7 0.0 2.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGO59112.1 - 3.7e-08 33.8 0.0 9.4e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2457 PF10446.9 EGO59114.1 - 0.019 14.2 9.2 0.023 13.9 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AAR2 PF05282.11 EGO59114.1 - 0.06 12.7 4.0 0.069 12.5 4.0 1.1 1 0 0 1 1 1 0 AAR2 protein DUF3807 PF12720.7 EGO59114.1 - 0.11 12.8 7.7 0.15 12.3 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Zip PF02535.22 EGO59114.1 - 0.2 10.8 5.7 0.24 10.6 5.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4834 PF16118.5 EGO59114.1 - 0.34 11.9 7.3 0.52 11.3 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 EGO59114.1 - 0.46 10.5 1.3 0.57 10.2 1.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 EGO59114.1 - 0.61 8.8 5.9 0.74 8.5 5.9 1.1 1 0 0 1 1 1 0 Presenilin SelP_N PF04592.14 EGO59114.1 - 0.65 9.4 9.4 0.94 8.8 9.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SLC12 PF03522.15 EGO59114.1 - 0.81 8.6 7.3 1 8.3 7.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GRP PF07172.11 EGO59114.1 - 1.1 9.9 9.7 1.9 9.3 9.7 1.3 1 0 0 1 1 1 0 Glycine rich protein family NPR3 PF03666.13 EGO59114.1 - 1.9 7.2 9.4 2.3 6.9 9.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Macoilin PF09726.9 EGO59114.1 - 1.9 6.9 9.2 2.4 6.6 9.2 1.2 1 0 0 1 1 1 0 Macoilin family GCD14 PF08704.10 EGO59114.1 - 2.8 7.5 5.6 3.6 7.2 5.6 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MMU163 PF17119.5 EGO59114.1 - 4.2 6.4 7.5 5.6 6.0 7.5 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis HCO3_cotransp PF00955.21 EGO59114.1 - 4.3 6.0 4.6 5.4 5.7 4.6 1.1 1 0 0 1 1 1 0 HCO3- transporter family ALMT PF11744.8 EGO59114.1 - 5.8 5.6 6.7 7 5.4 6.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zn_clus PF00172.18 EGO59115.1 - 3.1e-06 27.2 12.3 4.7e-06 26.6 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lon_C PF05362.13 EGO59117.1 - 1.1e-67 227.5 0.2 2e-67 226.7 0.2 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EGO59117.1 - 2.3e-28 99.5 0.0 4.4e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EGO59117.1 - 1.5e-23 83.6 0.0 3.8e-22 79.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGO59117.1 - 4.8e-09 36.3 0.0 1.2e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EGO59117.1 - 2e-07 30.9 0.0 4.7e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 EGO59117.1 - 2.1e-06 28.2 0.6 6.5e-06 26.6 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EGO59117.1 - 0.0002 21.2 0.0 0.00045 20.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EGO59117.1 - 0.00022 21.1 0.0 0.00053 19.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EGO59117.1 - 0.00025 21.2 0.0 0.00067 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGO59117.1 - 0.00025 20.8 0.1 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGO59117.1 - 0.00052 20.3 0.0 0.0081 16.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 EGO59117.1 - 0.0031 16.8 0.1 0.0059 15.9 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EGO59117.1 - 0.0032 17.7 0.0 0.0069 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGO59117.1 - 0.017 15.5 0.0 0.12 12.8 0.0 2.4 3 0 0 3 3 2 0 RNA helicase NACHT PF05729.12 EGO59117.1 - 0.039 13.9 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 EGO59117.1 - 0.043 13.8 0.0 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGO59117.1 - 0.049 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGO59117.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_PrkA PF08298.11 EGO59117.1 - 0.053 12.4 0.1 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain Rad17 PF03215.15 EGO59117.1 - 0.071 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 EGO59117.1 - 0.081 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 EGO59117.1 - 0.083 12.3 0.1 0.19 11.1 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 EGO59117.1 - 0.084 12.3 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein CENP-X PF09415.10 EGO59117.1 - 0.092 13.1 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 CENP-S associating Centromere protein X AAA_23 PF13476.6 EGO59117.1 - 0.093 13.2 5.6 0.17 12.4 0.0 2.8 1 1 0 2 2 1 0 AAA domain AAA_25 PF13481.6 EGO59117.1 - 0.12 12.0 0.1 0.31 10.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGO59117.1 - 0.12 12.3 0.1 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 EGO59117.1 - 0.17 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 EGO59117.1 - 0.19 11.2 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region COA2 PF17051.5 EGO59118.1 - 0.00036 20.5 0.0 0.00051 20.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 Metallophos PF00149.28 EGO59119.1 - 2.4e-32 113.1 0.1 3.8e-32 112.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGO59119.1 - 0.0021 18.5 0.1 0.0061 17.0 0.1 1.8 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ribonucleas_3_3 PF14622.6 EGO59120.1 - 5.5e-07 29.8 0.0 0.0045 17.1 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EGO59120.1 - 4.3e-06 27.3 0.0 2.5e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 EGO59120.1 - 2.5e-05 24.9 0.0 5.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif PLA2_B PF01735.18 EGO59121.1 - 3.4e-24 85.1 0.0 7.6e-24 84.0 0.0 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Septin PF00735.18 EGO59122.1 - 3.3e-119 397.3 0.2 3.3e-119 397.3 0.2 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EGO59122.1 - 9.5e-09 35.3 0.9 2.6e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO59122.1 - 5.9e-06 26.0 1.3 0.00018 21.1 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EGO59122.1 - 0.00028 21.4 3.0 0.022 15.2 0.0 2.6 2 1 0 2 2 2 1 ABC transporter AIG1 PF04548.16 EGO59122.1 - 0.00066 19.1 1.9 0.0015 17.9 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 EGO59122.1 - 0.0012 19.0 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EGO59122.1 - 0.0017 18.7 0.2 0.0048 17.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGO59122.1 - 0.0022 17.9 1.1 0.0022 17.9 1.1 3.3 3 1 0 3 3 2 1 RsgA GTPase Ras PF00071.22 EGO59122.1 - 0.0047 16.5 0.7 0.033 13.8 0.0 2.5 3 0 0 3 3 3 1 Ras family AAA_22 PF13401.6 EGO59122.1 - 0.01 16.1 1.1 0.033 14.5 0.0 2.4 2 2 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGO59122.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EGO59122.1 - 0.037 13.4 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 EGO59122.1 - 0.05 13.3 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EGO59122.1 - 0.053 13.6 8.9 0.76 9.8 0.0 3.7 4 1 0 4 4 3 0 Dynamin family Sigma54_activat PF00158.26 EGO59122.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP_bind_1 PF03029.17 EGO59122.1 - 0.073 12.8 3.0 3.5 7.3 0.1 3.2 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EGO59122.1 - 0.081 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EGO59122.1 - 0.082 13.3 0.6 0.5 10.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Exonuc_VII_L PF02601.15 EGO59122.1 - 0.4 10.2 6.7 0.59 9.6 6.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3987 PF13148.6 EGO59122.1 - 1.6 7.6 0.0 1.6 7.6 0.0 2.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3987) Atg14 PF10186.9 EGO59122.1 - 1.9 7.5 8.8 2.8 7.0 8.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 EGO59122.1 - 3.6 7.6 14.2 6.7 6.8 14.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_23 PF13476.6 EGO59122.1 - 4.1 7.9 14.2 5.3 7.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain DUF87 PF01935.17 EGO59122.1 - 4.1 7.4 7.2 4 7.5 0.0 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain Strep_SA_rep PF06696.11 EGO59122.1 - 4.5 7.4 6.7 1.5 8.9 3.0 2.1 1 1 1 2 2 2 0 Streptococcal surface antigen repeat S4 PF01479.25 EGO59123.1 - 3.8e-08 32.9 0.2 2.3e-07 30.4 0.2 2.4 1 1 0 1 1 1 1 S4 domain XRN_M PF17846.1 EGO59123.1 - 0.056 12.4 5.7 0.82 8.5 5.7 2.0 1 1 0 1 1 1 0 Xrn1 helical domain Menin PF05053.13 EGO59123.1 - 0.26 9.6 9.7 0.36 9.2 9.7 1.1 1 0 0 1 1 1 0 Menin FAM176 PF14851.6 EGO59123.1 - 6 6.5 7.7 14 5.3 5.4 2.2 2 0 0 2 2 2 0 FAM176 family La PF05383.17 EGO59124.1 - 2.4e-21 75.5 0.0 4.2e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EGO59124.1 - 1.2e-08 34.7 0.9 1.2e-08 34.7 0.9 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EGO59124.1 - 0.14 12.4 2.7 0.08 13.2 0.5 1.9 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Fungal_trans PF04082.18 EGO59125.1 - 2.9e-45 154.4 0.5 6.9e-45 153.1 0.0 1.9 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO59125.1 - 2.5e-08 33.9 6.3 5.6e-08 32.8 6.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HIT PF01230.23 EGO59126.1 - 1.9e-20 73.4 0.2 3e-20 72.8 0.2 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGO59126.1 - 0.0012 19.3 0.0 0.0021 18.5 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding MFS_1 PF07690.16 EGO59127.1 - 2.3e-29 102.4 30.0 2.5e-21 76.0 20.4 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO59127.1 - 4.9e-06 25.7 10.1 4.9e-06 25.7 10.1 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter DUF1751 PF08551.10 EGO59127.1 - 0.0051 17.4 0.4 0.032 14.8 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) DUF5326 PF17260.2 EGO59127.1 - 0.0098 16.0 2.7 0.15 12.2 1.0 3.4 2 0 0 2 2 2 1 Family of unknown function (DUF5326) Ferrochelatase PF00762.19 EGO59128.1 - 5.8e-103 344.3 0.0 6.8e-103 344.1 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.16 EGO59129.1 - 2.6e-45 154.6 0.0 5.4e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EGO59129.1 - 1.4e-35 123.1 0.0 2.3e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EGO59129.1 - 2.2e-29 102.0 2.3 9.4e-29 100.0 2.3 2.1 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 EGO59129.1 - 1.9e-11 43.5 0.2 5.1e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 SAP domain HeH PF12949.7 EGO59129.1 - 0.082 12.6 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 HeH/LEM domain DUF1907 PF08925.11 EGO59129.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1907) Zn_clus PF00172.18 EGO59130.1 - 1.2e-06 28.5 11.6 2.6e-06 27.4 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_N PF00134.23 EGO59132.1 - 0.0012 18.6 0.1 0.0043 16.8 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain CPSase_L_D2 PF02786.17 EGO59133.1 - 6.2e-115 382.0 0.4 4e-85 284.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EGO59133.1 - 1.3e-46 157.6 0.0 3.4e-46 156.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EGO59133.1 - 4.1e-46 157.2 0.0 8.2e-46 156.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 EGO59133.1 - 9.3e-46 155.5 0.1 2e-45 154.4 0.1 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 EGO59133.1 - 2.3e-38 131.3 0.0 5.5e-38 130.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EGO59133.1 - 1.7e-28 99.6 0.0 4.5e-28 98.3 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EGO59133.1 - 3.9e-23 81.5 0.1 1.9e-21 76.0 0.0 3.1 3 0 0 3 3 3 1 MGS-like domain ATP-grasp PF02222.22 EGO59133.1 - 1.4e-18 67.1 0.2 1.6e-09 37.6 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGO59133.1 - 1.8e-17 63.5 2.3 1.7e-08 34.2 0.1 2.9 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EGO59133.1 - 5.9e-11 42.2 0.0 2.7e-05 23.9 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EGO59133.1 - 2.7e-06 27.5 2.7 0.018 15.1 0.1 3.4 4 0 0 4 4 4 2 ATP-grasp domain Peptidase_C26 PF07722.13 EGO59133.1 - 2.8e-05 24.0 0.4 0.0034 17.2 0.4 2.7 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.19 EGO59133.1 - 0.00019 21.3 1.1 0.3 10.8 0.0 3.5 4 1 0 4 4 4 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.24 EGO59133.1 - 0.00019 21.3 0.0 0.013 15.3 0.0 3.0 3 0 0 3 3 3 1 DJ-1/PfpI family Ion_trans PF00520.31 EGO59135.1 - 3.1e-09 36.4 27.7 5.6e-09 35.6 27.7 1.4 1 0 0 1 1 1 1 Ion transport protein SE PF08491.10 EGO59138.1 - 9.1e-88 293.9 0.0 1.2e-87 293.5 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EGO59138.1 - 6e-10 38.9 1.1 9.3e-06 25.1 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 EGO59138.1 - 1.7e-09 37.8 0.4 2.9e-07 30.4 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EGO59138.1 - 8.1e-08 31.7 0.7 7.9e-07 28.5 0.7 2.0 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EGO59138.1 - 9e-06 25.3 0.4 1.4e-05 24.7 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO59138.1 - 1.2e-05 24.6 0.5 2.3e-05 23.7 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGO59138.1 - 1.4e-05 24.5 0.0 4.8e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EGO59138.1 - 1.6e-05 25.0 0.3 4.5e-05 23.6 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO59138.1 - 0.00088 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO59138.1 - 0.0017 18.9 0.3 0.004 17.7 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EGO59138.1 - 0.0097 15.6 0.2 0.019 14.6 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 EGO59138.1 - 0.014 14.3 0.2 4.5 6.0 0.2 2.3 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 EGO59138.1 - 0.018 13.8 0.1 0.025 13.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 EGO59138.1 - 0.026 13.6 0.5 0.51 9.3 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EGO59138.1 - 0.032 13.5 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EGO59138.1 - 0.036 14.1 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EGO59138.1 - 0.043 13.7 0.1 0.073 13.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 EGO59138.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 ThiF family NAD_Gly3P_dh_N PF01210.23 EGO59138.1 - 0.082 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.6 EGO59138.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPR_7 PF13176.6 EGO59139.1 - 0.0057 16.6 4.8 9.1 6.6 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO59139.1 - 0.029 14.9 8.8 0.14 12.7 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGO59139.1 - 0.11 13.2 0.8 8 7.2 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGO59139.1 - 0.21 12.5 9.2 22 6.2 0.0 6.4 8 0 0 8 8 8 0 Tetratricopeptide repeat Mito_carr PF00153.27 EGO59140.1 - 4.1e-61 202.9 3.4 2.4e-20 72.2 1.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S26 PF10502.9 EGO59141.1 - 0.00024 20.9 0.1 0.012 15.4 0.0 2.1 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 EIF_2_alpha PF07541.12 EGO59142.1 - 3.4e-37 127.1 0.0 6.8e-37 126.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EGO59142.1 - 8.6e-14 51.6 0.7 1.5e-13 50.8 0.7 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Troponin PF00992.20 EGO59142.1 - 0.0056 17.0 0.2 0.011 16.0 0.2 1.6 1 1 0 1 1 1 1 Troponin cNMP_binding PF00027.29 EGO59143.1 - 1.2e-28 99.0 0.5 9.3e-16 57.7 0.1 5.6 5 0 0 5 5 5 4 Cyclic nucleotide-binding domain Patatin PF01734.22 EGO59143.1 - 1.2e-13 51.7 10.0 8.4e-13 49.0 6.8 2.9 2 1 0 2 2 2 1 Patatin-like phospholipase Pyridoxal_deC PF00282.19 EGO59144.1 - 2.7e-93 312.7 0.0 3.3e-93 312.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Anoctamin PF04547.12 EGO59146.1 - 3.4e-120 401.9 11.8 4.2e-120 401.6 11.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel FMN_dh PF01070.18 EGO59147.1 - 2.3e-120 401.8 0.4 2.8e-120 401.5 0.4 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EGO59147.1 - 1.3e-23 82.9 0.0 2.4e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EGO59147.1 - 1e-07 31.5 0.1 1.7e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EGO59147.1 - 7.5e-05 21.9 0.4 0.00045 19.3 0.1 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EGO59147.1 - 0.0024 17.3 0.3 0.0024 17.3 0.3 1.7 2 0 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 EGO59147.1 - 0.0036 16.8 0.9 0.26 10.7 0.1 2.4 1 1 0 2 2 2 1 Histidine biosynthesis protein G3P_antiterm PF04309.12 EGO59147.1 - 0.038 13.4 0.0 0.34 10.3 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 EGO59147.1 - 0.039 13.3 0.1 4.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 EGO59147.1 - 0.11 11.6 0.0 2.2 7.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF561) Ras PF00071.22 EGO59148.1 - 4.3e-40 137.0 0.0 8e-38 129.6 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGO59148.1 - 6.1e-32 110.4 0.0 8.4e-32 109.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO59148.1 - 1.8e-10 40.6 0.0 2.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGO59148.1 - 0.00024 21.1 0.0 0.00043 20.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGO59148.1 - 0.0048 16.4 0.0 0.0067 15.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EGO59148.1 - 0.036 14.5 0.1 0.077 13.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EGO59148.1 - 0.051 13.3 0.2 0.097 12.4 0.2 1.5 1 1 0 1 1 1 0 AAA domain RTP1_C2 PF10304.9 EGO59148.1 - 0.064 13.0 0.3 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 Gtr1_RagA PF04670.12 EGO59148.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DLIC PF05783.11 EGO59148.1 - 0.19 10.5 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RsgA_GTPase PF03193.16 EGO59148.1 - 0.25 11.3 0.3 0.51 10.2 0.3 1.7 1 1 0 1 1 1 0 RsgA GTPase Ribonuclease_3 PF00636.26 EGO59149.1 - 1.8e-42 144.2 0.1 6.1e-20 71.8 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGO59149.1 - 1.3e-23 83.6 0.0 6e-10 39.4 0.0 3.8 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 EGO59149.1 - 6.4e-22 77.5 0.1 1.9e-20 72.8 0.1 3.0 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 EGO59149.1 - 2e-17 63.6 0.2 4.8e-17 62.3 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO59149.1 - 5.1e-15 55.9 0.0 1.3e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGO59149.1 - 5.6e-11 42.5 0.0 1.4e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGO59149.1 - 0.0019 18.4 0.0 0.0054 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 EGO59149.1 - 0.0043 16.3 0.0 0.0084 15.3 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Fructosamin_kin PF03881.14 EGO59149.1 - 0.088 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase DUF2322 PF10084.9 EGO59149.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) PNP_phzG_C PF10590.9 EGO59150.1 - 9.8e-21 73.6 3.0 9.8e-21 73.6 3.0 2.4 3 1 0 3 3 3 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EGO59150.1 - 1.5e-12 47.5 0.0 7.7e-12 45.2 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Sec63 PF02889.16 EGO59151.1 - 2.3e-133 443.2 0.0 4.6e-81 271.8 0.1 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EGO59151.1 - 2.9e-49 167.2 2.4 1.4e-25 90.1 0.2 3.7 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 EGO59151.1 - 5.8e-21 75.2 0.0 3.2e-10 40.3 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGO59151.1 - 8.7e-17 61.5 0.8 1.8e-06 28.3 0.0 4.9 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGO59151.1 - 1.4e-07 31.8 0.1 0.024 14.9 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EGO59151.1 - 1.2e-06 28.4 0.1 0.043 13.5 0.2 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGO59151.1 - 4e-05 24.0 0.4 0.0042 17.4 0.4 2.6 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 EGO59151.1 - 0.00015 21.9 0.1 0.00082 19.5 0.0 2.3 2 0 0 2 2 2 1 N-terminal helicase PWI domain AAA PF00004.29 EGO59151.1 - 0.0016 18.9 0.6 2.1 8.8 0.0 4.6 5 1 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) NikR_C PF08753.11 EGO59151.1 - 0.17 12.0 0.3 6.1 7.1 0.0 2.8 2 0 0 2 2 2 0 NikR C terminal nickel binding domain DUF3381 PF11861.8 EGO59151.1 - 1.7 8.4 4.1 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) SUIM_assoc PF16619.5 EGO59151.1 - 5.4 7.2 15.0 2.2 8.4 2.8 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Activator_LAG-3 PF11498.8 EGO59151.1 - 7.5 5.4 14.6 8.9 5.2 3.3 2.5 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Ras PF00071.22 EGO59152.1 - 7.9e-65 217.4 0.0 1.2e-64 216.8 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGO59152.1 - 5.7e-34 116.9 0.0 1.3e-33 115.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO59152.1 - 2.4e-13 49.9 0.0 2.8e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGO59152.1 - 8.4e-06 25.4 0.0 2.5e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGO59152.1 - 0.00027 20.4 0.0 0.0003 20.2 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGO59152.1 - 0.00045 20.2 0.2 0.45 10.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGO59152.1 - 0.002 18.2 0.0 0.0069 16.5 0.0 1.8 1 1 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGO59152.1 - 0.016 14.6 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGO59152.1 - 0.072 12.6 0.0 0.37 10.3 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 EGO59152.1 - 0.14 12.4 0.1 0.49 10.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain NCA2 PF08637.10 EGO59153.1 - 4.3e-105 351.0 0.1 7.9e-105 350.2 0.1 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.13 EGO59154.1 - 2.9e-25 89.2 13.9 2.9e-25 89.2 13.9 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Amidohydro_1 PF01979.20 EGO59155.1 - 1.2e-41 143.2 0.6 1.4e-41 142.9 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGO59155.1 - 3e-14 53.3 2.4 1.3e-11 44.7 0.2 2.1 2 0 0 2 2 2 2 Amidohydrolase family AP_endonuc_2 PF01261.24 EGO59155.1 - 0.052 13.0 0.3 1.8 7.9 0.3 2.8 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel bZIP_1 PF00170.21 EGO59156.1 - 8.7e-08 32.2 10.4 1.2e-06 28.5 10.4 2.2 1 1 0 1 1 1 1 bZIP transcription factor SUIM_assoc PF16619.5 EGO59156.1 - 0.0095 16.0 0.0 0.051 13.6 0.0 2.3 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 bZIP_2 PF07716.15 EGO59156.1 - 0.11 12.6 11.7 12 6.0 9.8 2.7 2 1 0 2 2 2 0 Basic region leucine zipper Ribosomal_L30_N PF08079.12 EGO59156.1 - 1.1 9.5 8.4 2.2 8.6 8.4 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Profilin PF00235.19 EGO59158.1 - 1e-45 155.1 0.4 1.1e-45 155.0 0.4 1.0 1 0 0 1 1 1 1 Profilin YL1_C PF08265.11 EGO59159.1 - 7.6e-16 57.6 0.1 1.2e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DASH_Dad4 PF08650.10 EGO59160.1 - 3.6e-33 113.4 8.8 3.9e-33 113.2 8.8 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 Biotin_carb_C PF02785.19 EGO59160.1 - 0.037 14.1 0.1 0.041 14.0 0.1 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain Actin PF00022.19 EGO59161.1 - 3.1e-55 187.5 0.0 7.2e-52 176.4 0.0 2.4 1 1 0 1 1 1 1 Actin AAA PF00004.29 EGO59162.1 - 1.3e-50 171.2 0.0 7.9e-39 133.1 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO59162.1 - 2.8e-12 46.3 0.9 4.5e-08 32.8 0.4 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGO59162.1 - 9.7e-08 32.6 1.0 0.0037 17.7 0.0 4.1 3 2 2 5 5 5 2 AAA ATPase domain AAA_25 PF13481.6 EGO59162.1 - 0.00022 20.9 4.8 0.91 9.1 0.1 4.0 2 2 2 4 4 4 2 AAA domain AAA_28 PF13521.6 EGO59162.1 - 0.00024 21.4 0.0 0.017 15.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGO59162.1 - 0.0026 18.1 0.0 3.2 8.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_2 PF07724.14 EGO59162.1 - 0.0027 17.8 0.0 0.069 13.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) ATPase PF06745.13 EGO59162.1 - 0.0032 16.9 1.1 0.027 13.8 0.1 2.6 3 0 0 3 3 3 1 KaiC RuvB_N PF05496.12 EGO59162.1 - 0.004 16.9 0.0 0.27 10.9 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGO59162.1 - 0.0044 17.0 0.2 0.38 10.8 0.0 3.2 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGO59162.1 - 0.0072 16.6 5.1 8.1 6.7 2.0 4.6 3 2 1 4 4 4 1 AAA domain Bac_DnaA PF00308.18 EGO59162.1 - 0.0086 15.9 2.7 0.65 9.8 0.0 3.2 3 1 0 3 3 2 1 Bacterial dnaA protein AFG1_ATPase PF03969.16 EGO59162.1 - 0.014 14.3 0.0 0.062 12.2 0.0 1.9 2 0 0 2 2 2 0 AFG1-like ATPase NACHT PF05729.12 EGO59162.1 - 0.018 14.9 1.8 0.41 10.6 0.7 3.0 2 1 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 EGO59162.1 - 0.037 14.5 0.0 0.16 12.5 0.0 2.1 2 0 0 2 2 2 0 ABC transporter IstB_IS21 PF01695.17 EGO59162.1 - 0.042 13.6 0.0 5.1 6.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 EGO59162.1 - 0.069 13.1 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 EGO59162.1 - 0.15 11.6 0.1 8.1 5.9 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGO59162.1 - 0.16 11.3 1.5 0.78 9.1 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PAS_3 PF08447.12 EGO59164.1 - 0.00014 22.1 0.0 0.048 13.9 0.0 2.4 2 0 0 2 2 2 1 PAS fold DNA_pol_phi PF04931.13 EGO59164.1 - 0.042 12.0 11.6 0.057 11.5 11.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi PAS PF00989.25 EGO59164.1 - 0.05 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 PAS fold CDC45 PF02724.14 EGO59164.1 - 0.057 11.7 10.4 0.089 11.1 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein PAS_9 PF13426.7 EGO59164.1 - 0.074 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain CENP-B_dimeris PF09026.10 EGO59164.1 - 0.7 10.3 16.4 1.4 9.3 16.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain S-antigen PF05756.11 EGO59164.1 - 1.5 9.2 5.5 2.9 8.3 5.5 1.4 1 0 0 1 1 1 0 S-antigen protein NOA36 PF06524.12 EGO59164.1 - 2.3 7.5 9.6 3.9 6.7 9.6 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 EGO59164.1 - 7.3 5.9 13.4 13 5.1 13.4 1.3 1 0 0 1 1 1 0 SDA1 eIF-3c_N PF05470.12 EGO59164.1 - 9.3 4.4 8.5 15 3.7 8.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SMK-1 PF04802.15 EGO59165.1 - 8.7e-77 257.3 0.7 8.7e-77 257.3 0.7 2.7 3 0 0 3 3 3 1 Component of IIS longevity pathway SMK-1 CttA_N PF18244.1 EGO59168.1 - 0.11 13.0 0.3 0.22 12.0 0.3 1.5 1 0 0 1 1 1 0 Cellulose-binding protein CttA N-terminal domain Glycos_transf_2 PF00535.26 EGO59169.1 - 4.2e-23 82.0 0.0 1.7e-22 80.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGO59169.1 - 2.3e-08 34.2 0.0 4.4e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EGO59169.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF5360 PF17314.2 EGO59170.1 - 0.18 11.9 4.7 3.5 7.7 1.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5360) DPM3 PF08285.11 EGO59170.1 - 8.1 6.7 17.4 0.45 10.8 1.3 3.7 2 2 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Sugar_tr PF00083.24 EGO59171.1 - 3.5e-92 309.6 16.9 4e-92 309.4 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO59171.1 - 3e-32 111.9 42.5 1.1e-26 93.6 23.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.7 EGO59171.1 - 3.7 7.7 25.5 0.094 12.9 7.3 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3792) AnmK PF03702.14 EGO59172.1 - 9.6e-85 284.9 0.0 1.1e-84 284.6 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Zn_clus PF00172.18 EGO59173.1 - 2.8e-07 30.5 6.5 2.8e-07 30.5 6.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGO59173.1 - 6e-05 22.2 0.1 8.9e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_tran PF00005.27 EGO59174.1 - 4.5e-47 160.0 0.2 2.8e-28 99.1 0.1 2.9 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 EGO59174.1 - 6.5e-46 157.2 25.5 9e-23 81.3 1.3 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 EGO59174.1 - 5.8e-09 35.7 3.3 0.0011 18.5 0.7 4.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EGO59174.1 - 1.7e-06 27.7 0.0 0.051 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EGO59174.1 - 3.1e-05 24.6 2.4 0.0057 17.2 0.6 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGO59174.1 - 3.1e-05 23.9 0.0 0.099 12.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGO59174.1 - 5.3e-05 22.9 2.9 0.065 13.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGO59174.1 - 0.0011 19.3 0.1 1.7 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 EGO59174.1 - 0.0012 18.8 0.6 0.68 9.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.23 EGO59174.1 - 0.003 17.6 0.1 0.27 11.3 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EGO59174.1 - 0.0055 17.0 1.0 2.5 8.4 0.1 3.1 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.6 EGO59174.1 - 0.0063 16.4 4.0 8.8 6.0 0.7 3.6 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 EGO59174.1 - 0.01 15.9 1.4 2.9 7.9 0.1 3.0 3 0 0 3 3 3 0 Dynamin family DUF87 PF01935.17 EGO59174.1 - 0.01 16.0 0.2 0.01 16.0 0.2 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 EGO59174.1 - 0.015 14.7 0.2 0.12 11.7 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 EGO59174.1 - 0.015 14.5 4.5 4.7 6.3 0.0 4.3 5 0 0 5 5 5 0 NB-ARC domain Pox_A32 PF04665.12 EGO59174.1 - 0.028 13.9 3.2 0.94 8.9 0.2 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein DUF468 PF04318.12 EGO59174.1 - 0.037 14.7 0.2 0.9 10.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF468) Viral_helicase1 PF01443.18 EGO59174.1 - 0.04 13.7 0.0 14 5.4 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase SbcCD_C PF13558.6 EGO59174.1 - 0.048 13.9 0.1 10 6.5 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 EGO59174.1 - 0.062 12.9 2.0 4.5 6.8 0.6 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 EGO59174.1 - 0.071 12.1 0.2 3.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 EGO59174.1 - 0.11 12.7 0.2 15 5.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EGO59174.1 - 0.12 12.1 0.6 7.5 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EGO59174.1 - 0.13 11.5 0.1 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 EGO59174.1 - 0.14 11.9 0.0 6.8 6.4 0.0 2.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_15 PF13175.6 EGO59174.1 - 0.18 11.5 0.3 8.5 6.0 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain DAP3 PF10236.9 EGO59174.1 - 0.24 10.5 0.6 19 4.3 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ABC_ATPase PF09818.9 EGO59174.1 - 2.2 7.0 4.4 1.8 7.3 0.0 2.7 4 0 0 4 4 3 0 Predicted ATPase of the ABC class Glyco_hydro_17 PF00332.18 EGO59175.1 - 2.7e-07 30.5 0.3 5.2e-07 29.6 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Zip PF02535.22 EGO59176.1 - 1.5e-60 205.2 9.1 1.2e-59 202.2 9.1 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter FUSC_2 PF13515.6 EGO59176.1 - 5.9 7.0 9.1 0.79 9.9 3.2 2.6 3 1 1 4 4 4 0 Fusaric acid resistance protein-like Bul1_C PF04426.12 EGO59177.1 - 0.0007 19.1 0.2 0.0017 17.8 0.1 1.6 2 0 0 2 2 2 1 Bul1 C terminus Arrestin_N PF00339.29 EGO59177.1 - 0.0063 16.6 0.0 0.022 14.8 0.0 1.8 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Metallophos PF00149.28 EGO59178.1 - 1.3e-11 45.4 1.4 2.1e-11 44.7 1.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGO59178.1 - 1.2e-05 25.6 0.3 9.3e-05 22.7 0.3 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain EMP70 PF02990.16 EGO59179.1 - 3e-208 692.7 1.9 3.6e-208 692.4 1.9 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Peptidase_C12 PF01088.21 EGO59182.1 - 2.4e-56 190.9 0.0 2.8e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SUV3_C PF12513.8 EGO59183.1 - 1.5e-18 66.4 1.7 1.9e-18 66.1 0.3 2.0 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 EGO59183.1 - 4.8e-09 36.5 0.0 1.1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 EGO59183.1 - 2.7e-07 30.3 0.0 5.7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 TK PF00265.18 EGO59183.1 - 0.046 13.6 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase CARMIL_C PF16000.5 EGO59183.1 - 2.4 7.7 10.0 0.31 10.6 5.4 1.7 2 0 0 2 2 2 0 CARMIL C-terminus Synaptobrevin PF00957.21 EGO59184.1 - 1.4e-31 108.1 0.6 1.9e-31 107.7 0.6 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGO59184.1 - 2.9e-30 104.1 0.0 5.6e-30 103.2 0.0 1.5 2 0 0 2 2 2 1 Regulated-SNARE-like domain adh_short PF00106.25 EGO59185.1 - 2.2e-15 56.7 0.0 1.6e-14 53.8 0.0 2.3 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO59185.1 - 1.9e-05 24.4 0.0 9.1e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO59185.1 - 6.3e-05 23.0 0.0 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO59185.1 - 0.00052 19.5 0.0 0.0016 18.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family UvrD-helicase PF00580.21 EGO59185.1 - 0.87 9.0 5.6 1.6 8.2 5.6 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain G-patch PF01585.23 EGO59186.1 - 3e-07 30.2 0.3 5.4e-07 29.4 0.3 1.5 1 0 0 1 1 1 1 G-patch domain Yip1 PF04893.17 EGO59187.1 - 4.3e-14 52.6 10.3 6.7e-14 52.0 10.3 1.4 1 0 0 1 1 1 1 Yip1 domain 7TM_transglut PF14402.6 EGO59187.1 - 0.052 13.0 7.2 0.071 12.6 7.2 1.2 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase DUF1282 PF06930.12 EGO59187.1 - 0.16 11.7 12.0 0.29 10.9 12.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) DUF2070 PF09843.9 EGO59187.1 - 0.25 9.6 8.7 0.3 9.3 8.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Na_Ca_ex PF01699.24 EGO59188.1 - 3.4e-26 92.0 22.6 1.7e-13 50.8 7.6 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF979 PF06166.12 EGO59188.1 - 0.0044 16.2 4.0 0.028 13.6 0.8 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF979) DUF1298 PF06974.13 EGO59188.1 - 0.023 14.6 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) DUF872 PF05915.12 EGO59188.1 - 0.38 10.9 1.8 8.6 6.6 0.2 2.9 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DEAD PF00270.29 EGO59189.1 - 6e-26 91.3 0.0 1.2e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 EGO59189.1 - 1.2e-21 77.2 0.2 3.3e-21 75.8 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 EGO59189.1 - 1.7e-13 50.9 0.1 6.7e-13 49.0 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO59189.1 - 3.8e-08 33.5 0.0 6.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 EGO59189.1 - 6e-05 23.4 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like Lipase_GDSL PF00657.22 EGO59190.1 - 1.3e-10 41.6 0.0 2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EGO59190.1 - 0.0034 17.8 1.6 0.0083 16.5 1.6 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Phosphatase PF15698.5 EGO59190.1 - 0.2 10.8 0.1 0.28 10.3 0.1 1.2 1 0 0 1 1 1 0 Phosphatase RabGAP-TBC PF00566.18 EGO59192.1 - 1.2e-48 165.7 0.3 3.7e-47 160.7 0.0 3.0 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF1664 PF07889.12 EGO59192.1 - 0.0007 19.6 9.2 0.00078 19.5 3.3 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 EGO59192.1 - 0.0084 16.3 6.8 0.0084 16.3 6.8 3.7 4 0 0 4 4 4 1 Tropomyosin like DUF4200 PF13863.6 EGO59192.1 - 0.014 15.8 11.2 0.014 15.8 11.2 4.1 3 2 1 5 5 5 0 Domain of unknown function (DUF4200) Histone_HNS PF00816.21 EGO59192.1 - 0.48 11.3 0.0 0.48 11.3 0.0 4.8 4 2 0 4 4 4 0 H-NS histone family RAP1 PF07218.11 EGO59192.1 - 2.2 6.5 15.6 0.2 9.9 9.8 2.0 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Occludin_ELL PF07303.13 EGO59192.1 - 3.7 8.3 8.0 32 5.3 1.5 3.1 2 0 0 2 2 2 0 Occludin homology domain Fez1 PF06818.15 EGO59192.1 - 4.2 7.8 39.0 0.26 11.7 9.3 3.8 3 1 0 3 3 3 0 Fez1 Laminin_II PF06009.12 EGO59192.1 - 8.4 6.4 17.0 0.22 11.6 3.6 3.2 3 0 0 3 3 3 0 Laminin Domain II Reticulon PF02453.17 EGO59193.1 - 9.2e-33 113.4 3.8 1.6e-32 112.7 3.8 1.4 1 0 0 1 1 1 1 Reticulon FUSC_2 PF13515.6 EGO59193.1 - 1.2 9.3 7.7 0.27 11.3 2.0 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein-like Aminotran_1_2 PF00155.21 EGO59194.1 - 1.7e-66 224.9 0.0 2e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGO59194.1 - 0.16 10.5 0.1 0.29 9.6 0.0 1.4 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 EGO59194.1 - 0.19 10.5 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Allinase Sugar_tr PF00083.24 EGO59196.1 - 1.7e-118 396.3 31.3 2e-118 396.1 31.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO59196.1 - 1.3e-19 70.3 38.9 5.2e-17 61.8 30.0 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily PUCC PF03209.15 EGO59196.1 - 0.0025 16.9 7.2 0.0025 16.9 7.2 1.8 2 0 0 2 2 2 1 PUCC protein Xpo1 PF08389.12 EGO59197.1 - 6.8e-28 97.6 0.5 4.2e-27 95.0 0.2 2.6 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 EGO59197.1 - 1e-08 34.9 2.1 1.9e-07 30.9 0.3 3.4 3 1 1 4 4 4 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 EGO59197.1 - 0.0034 16.0 2.6 0.19 10.2 0.1 2.9 2 2 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 EGO59197.1 - 0.0094 16.4 11.0 0.27 11.8 0.0 6.5 8 0 0 8 8 8 1 HEAT-like repeat NUC173 PF08161.12 EGO59197.1 - 0.079 12.6 1.2 27 4.4 0.0 4.0 4 1 0 4 4 4 0 NUC173 domain GAT PF03127.14 EGO59197.1 - 0.23 11.8 1.6 3.6 8.0 0.0 3.4 3 0 0 3 3 3 0 GAT domain 5-FTHF_cyc-lig PF01812.20 EGO59198.1 - 4.7e-22 78.7 0.0 6.2e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family OPT PF03169.15 EGO59199.1 - 1.1e-220 734.5 37.6 1.3e-220 734.3 37.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein His_Phos_2 PF00328.22 EGO59200.1 - 8.7e-58 196.5 0.0 1.1e-57 196.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) JmjC PF02373.22 EGO59201.1 - 0.044 14.2 1.1 0.052 14.0 1.1 1.1 1 0 0 1 1 1 0 JmjC domain, hydroxylase RCR PF12273.8 EGO59202.1 - 0.081 13.6 3.2 0.33 11.6 3.1 2.0 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF2749 PF10907.8 EGO59202.1 - 0.75 10.0 4.4 0.61 10.3 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Inositol_P PF00459.25 EGO59203.1 - 2.5e-63 214.1 0.0 3.1e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family End3 PF12761.7 EGO59204.1 - 2.5e-77 259.6 4.6 3.4e-77 259.1 4.6 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 EGO59204.1 - 4.2e-50 168.0 0.0 1.2e-48 163.4 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EGO59204.1 - 2.9e-07 29.6 0.2 8.4e-07 28.1 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EGO59204.1 - 8.7e-06 26.1 0.0 3.5e-05 24.2 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGO59204.1 - 0.00039 20.1 0.0 0.0026 17.5 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EGO59204.1 - 0.00058 19.7 0.0 0.0037 17.1 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair MDMPI_N PF11716.8 EGO59204.1 - 0.0095 16.6 1.7 0.022 15.4 0.0 2.3 2 1 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain EF-hand_5 PF13202.6 EGO59204.1 - 0.019 14.4 0.1 0.061 12.8 0.1 1.8 1 0 0 1 1 1 0 EF hand CSN5_C PF18323.1 EGO59204.1 - 3.1 8.8 5.3 2.1 9.3 2.3 2.2 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain UPF0242 PF06785.11 EGO59204.1 - 5.2 7.1 7.3 11 6.1 7.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ACBP PF00887.19 EGO59205.1 - 8.1e-25 86.9 2.5 9.4e-25 86.7 2.5 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Tyr-DNA_phospho PF06087.12 EGO59206.1 - 7e-161 535.8 0.0 8.4e-161 535.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Thioredoxin PF00085.20 EGO59207.1 - 9.2e-39 131.6 0.1 6.3e-23 80.7 0.0 3.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EGO59207.1 - 3e-07 30.5 0.0 0.004 17.1 0.0 3.7 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGO59207.1 - 2.8e-05 24.2 1.1 0.066 13.4 0.2 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EGO59207.1 - 0.00019 21.7 0.2 2.9 8.3 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGO59207.1 - 0.00023 21.6 2.3 0.12 12.9 0.1 4.0 2 1 1 3 3 3 1 Thioredoxin-like domain HyaE PF07449.11 EGO59207.1 - 0.061 13.3 0.0 6.8 6.7 0.0 3.1 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 EGO59207.1 - 0.079 13.0 2.7 0.15 12.1 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin domain 7TM_GPCR_Srh PF10318.9 EGO59207.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh FR47 PF08445.10 EGO59208.1 - 3.9e-08 33.1 0.0 7.4e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EGO59208.1 - 8.3e-08 32.2 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO59208.1 - 4.2e-07 30.2 0.0 7.5e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO59208.1 - 1.8e-05 25.0 0.0 2.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EGO59208.1 - 0.15 12.0 0.1 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 EGO59208.1 - 0.16 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PLDc_2 PF13091.6 EGO59209.1 - 1.5e-16 60.5 0.0 2.5e-06 27.4 0.0 3.9 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 EGO59209.1 - 2e-13 49.9 1.0 2.2e-05 24.4 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 EGO59209.1 - 0.19 10.9 0.8 0.38 9.9 0.0 1.7 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB MFS_1 PF07690.16 EGO59210.1 - 8.2e-34 117.1 25.2 4.9e-27 94.8 2.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO59210.1 - 1.1e-07 31.1 5.8 1.1e-07 31.1 5.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EGO59210.1 - 0.016 14.1 13.6 0.029 13.2 2.8 2.5 2 0 0 2 2 2 0 MFS_1 like family MFS_3 PF05977.13 EGO59210.1 - 0.59 8.5 7.7 2.6 6.4 3.2 3.1 2 2 1 3 3 3 0 Transmembrane secretion effector DNA_topoisoIV PF00521.20 EGO59212.1 - 4e-124 414.8 0.0 6.6e-124 414.0 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EGO59212.1 - 3.6e-47 159.8 1.4 3.6e-47 159.8 1.4 2.3 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EGO59212.1 - 2.2e-22 79.3 0.6 4.9e-22 78.2 0.6 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EGO59212.1 - 1.8e-11 44.5 0.1 1.6e-10 41.4 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EGO59212.1 - 2.6e-05 24.4 0.0 9e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 EGO59212.1 - 0.0079 16.0 0.4 0.17 11.7 0.1 3.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_20 PF14561.6 EGO59212.1 - 0.17 12.2 0.1 0.17 12.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DAGK_cat PF00781.24 EGO59213.1 - 5.9e-09 35.6 0.0 2.6e-08 33.6 0.0 2.1 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain TRM PF02005.16 EGO59214.1 - 4e-108 362.0 0.0 3e-95 319.6 0.0 2.1 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.14 EGO59214.1 - 0.11 12.0 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain PRTP PF01366.18 EGO59214.1 - 0.3 9.1 2.8 5.9 4.8 4.4 2.0 2 0 0 2 2 2 0 Herpesvirus processing and transport protein Presenilin PF01080.17 EGO59214.1 - 1.5 7.5 8.2 1.6 7.4 5.4 1.9 2 0 0 2 2 2 0 Presenilin SLATT_fungal PF18142.1 EGO59215.1 - 1.1e-28 99.6 0.0 1.5e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain PBD PF00786.28 EGO59216.1 - 0.18 12.2 1.3 1.2 9.5 1.3 2.4 1 1 0 1 1 1 0 P21-Rho-binding domain Sec62 PF03839.16 EGO59217.1 - 7.7e-73 244.6 1.0 7.7e-73 244.6 1.0 2.0 2 0 0 2 2 2 1 Translocation protein Sec62 UreE_C PF05194.12 EGO59217.1 - 0.024 15.1 11.0 0.061 13.8 11.0 1.7 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain PIEZO PF15917.5 EGO59217.1 - 0.52 9.7 5.7 1 8.8 5.7 1.4 1 0 0 1 1 1 0 Piezo SelP_N PF04592.14 EGO59217.1 - 1.1 8.7 7.4 2.2 7.6 7.4 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Abhydrolase_1 PF00561.20 EGO59218.1 - 7.9e-16 58.5 0.0 6.3e-15 55.5 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO59218.1 - 1e-14 54.4 0.0 5.9e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGO59218.1 - 1.6e-14 55.1 2.9 1.9e-13 51.5 0.6 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 EGO59218.1 - 5.2e-06 26.0 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 EGO59218.1 - 6e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 EGO59218.1 - 0.0036 17.1 0.0 1.1 9.0 0.0 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 EGO59218.1 - 0.025 14.1 0.0 0.072 12.6 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 EGO59218.1 - 0.045 13.5 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EGO59218.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 EGO59218.1 - 0.07 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 EGO59218.1 - 0.11 12.0 0.0 12 5.3 0.0 2.5 2 1 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.20 EGO59218.1 - 0.14 12.2 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 Thioesterase domain TPR_10 PF13374.6 EGO59218.1 - 0.34 10.8 3.3 0.22 11.4 0.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Spo7 PF03907.13 EGO59219.1 - 4.7e-92 307.5 0.0 7.5e-92 306.8 0.0 1.3 1 0 0 1 1 1 1 Spo7-like protein DSPc PF00782.20 EGO59220.1 - 8.4e-10 38.6 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EGO59220.1 - 0.00012 22.3 0.0 0.00021 21.5 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain RNA_pol_3_Rpc31 PF11705.8 EGO59221.1 - 0.019 15.3 9.2 0.19 11.9 2.7 3.2 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 EGO59221.1 - 0.62 8.1 8.2 1.1 7.3 8.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 EGO59221.1 - 1.7 7.7 9.1 3.6 6.6 9.1 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-B_dimeris PF09026.10 EGO59221.1 - 1.8 9.0 11.1 5.7 7.4 11.1 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EGO59221.1 - 6.4 6.0 5.7 14 4.9 5.7 1.5 1 0 0 1 1 1 0 NOA36 protein p450 PF00067.22 EGO59223.1 - 1e-66 225.6 0.0 1.4e-66 225.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pec_lyase_C PF00544.19 EGO59223.1 - 1.2e-24 87.1 5.2 3.7e-23 82.2 5.2 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EGO59223.1 - 0.00094 19.1 5.8 0.002 18.0 5.8 1.5 1 0 0 1 1 1 1 Right handed beta helix region DUF1996 PF09362.10 EGO59224.1 - 1.8e-55 188.5 3.3 5.7e-55 186.9 0.4 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1996) Zn_clus PF00172.18 EGO59225.1 - 0.0022 18.1 8.4 0.0042 17.2 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sld5 PF05916.11 EGO59227.1 - 4.2e-31 107.6 0.0 9.6e-31 106.5 0.0 1.6 1 1 0 1 1 1 1 GINS complex protein VP_N-CPKC PF11475.8 EGO59230.1 - 0.17 11.8 0.6 2.8 7.9 0.1 2.6 2 0 0 2 2 2 0 Virion protein N terminal domain Glyco_hydro_76 PF03663.14 EGO59231.1 - 4.2e-141 470.7 0.2 5.8e-141 470.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EGO59231.1 - 0.1 11.7 4.3 0.6 9.1 0.4 2.7 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 OB_NTP_bind PF07717.16 EGO59232.1 - 3.5e-24 85.0 0.0 8.9e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EGO59232.1 - 8.6e-24 83.9 0.1 8.6e-24 83.9 0.1 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) S1 PF00575.23 EGO59232.1 - 2.1e-12 47.2 0.8 5.5e-12 45.9 0.8 1.7 1 0 0 1 1 1 1 S1 RNA binding domain RimM PF01782.18 EGO59232.1 - 0.036 14.3 0.3 0.16 12.2 0.3 2.1 2 0 0 2 2 2 0 RimM N-terminal domain Red1 PF07964.11 EGO59232.1 - 4.5 5.4 8.8 0.38 8.9 1.3 2.0 2 0 0 2 2 2 0 Rec10 / Red1 Pmp3 PF01679.17 EGO59233.1 - 1e-18 67.2 9.2 1.5e-18 66.7 9.2 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Arb1 PF09692.10 EGO59234.1 - 1e-133 446.4 0.0 1.3e-133 446.1 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.16 EGO59235.1 - 8.6e-54 182.4 0.0 1.5e-53 181.6 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase CLP1_P PF16575.5 EGO59236.1 - 6.2e-26 91.4 0.0 2.7e-25 89.3 0.0 1.9 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 EGO59236.1 - 1.5e-21 77.0 0.0 4.1e-21 75.6 0.0 1.8 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 EGO59236.1 - 6.6e-19 67.9 0.0 1.1e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor AAA PF00004.29 EGO59236.1 - 0.00028 21.3 0.1 0.00055 20.4 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGO59236.1 - 0.00032 21.3 0.0 0.00066 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO59236.1 - 0.00086 19.7 0.0 0.0021 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGO59236.1 - 0.0014 18.4 0.1 0.0028 17.4 0.1 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGO59236.1 - 0.0038 17.2 0.0 0.0075 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGO59236.1 - 0.0062 16.8 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGO59236.1 - 0.0097 15.7 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.27 EGO59236.1 - 0.013 16.1 0.0 0.027 15.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 EGO59236.1 - 0.016 14.6 0.2 0.032 13.6 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGO59236.1 - 0.018 14.7 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EGO59236.1 - 0.018 14.8 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 EGO59236.1 - 0.03 14.6 0.0 0.075 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGO59236.1 - 0.031 14.7 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 EGO59236.1 - 0.038 14.2 1.1 0.066 13.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain Roc PF08477.13 EGO59236.1 - 0.089 13.0 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Git3 PF11710.8 EGO59237.1 - 1.1e-54 185.3 11.0 1.9e-54 184.6 11.0 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EGO59237.1 - 4.5e-28 97.1 0.3 9.3e-28 96.1 0.3 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7TM_GPCR_Srsx PF10320.9 EGO59237.1 - 0.0014 18.1 0.2 0.0024 17.3 0.2 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2834 PF11196.8 EGO59237.1 - 0.011 16.1 1.0 0.052 13.9 0.0 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF2834) GATase PF00117.28 EGO59238.1 - 1.2e-11 44.7 0.1 1.9e-11 44.1 0.1 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DHHA2 PF02833.14 EGO59239.1 - 3.5e-39 134.3 0.1 5e-39 133.8 0.1 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EGO59239.1 - 2.5e-09 37.3 0.0 4.2e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 DHH family RsfS PF02410.15 EGO59240.1 - 2.9e-15 56.5 0.0 1.2e-14 54.5 0.0 2.1 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation mRNA_stabil PF13929.6 EGO59240.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 mRNA stabilisation RNA_pol PF00940.19 EGO59241.1 - 8.3e-189 627.7 0.0 2.6e-188 626.0 0.0 1.9 3 0 0 3 3 3 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EGO59241.1 - 7.6e-102 341.1 0.3 7.6e-102 341.1 0.3 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal SUIM_assoc PF16619.5 EGO59241.1 - 0.013 15.6 5.8 0.051 13.6 5.8 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF719 PF05334.13 EGO59241.1 - 5 7.3 7.2 7.1 6.8 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF719) tRNA_bind PF01588.20 EGO59242.1 - 7.7e-23 80.4 0.3 1.9e-22 79.1 0.3 1.7 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 EGO59242.1 - 0.0008 19.6 0.6 0.0015 18.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO59242.1 - 0.0055 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SNF2_N PF00176.23 EGO59243.1 - 7e-66 222.3 0.5 1.4e-65 221.3 0.5 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO59243.1 - 2.3e-22 79.4 0.0 8.4e-22 77.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO59243.1 - 3.8e-07 30.3 0.2 1.3e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGO59243.1 - 2.5e-05 23.6 0.0 2.5e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 EGO59243.1 - 0.0016 17.7 2.7 0.0066 15.6 0.0 2.8 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 EGO59243.1 - 0.0023 17.6 0.0 0.0077 15.9 0.0 1.9 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AT_hook PF02178.19 EGO59243.1 - 1.3 9.2 6.0 7.5 6.8 6.0 2.4 1 0 0 1 1 1 0 AT hook motif MFS_1 PF07690.16 EGO59244.1 - 4.5e-36 124.5 39.6 1.1e-35 123.3 25.9 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MWFE PF15879.5 EGO59244.1 - 0.0033 17.5 0.3 0.022 14.9 0.0 2.6 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase MWFE subunit HET PF06985.11 EGO59245.1 - 2.4e-13 50.7 5.3 6.3e-11 42.8 0.5 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FMN_red PF03358.15 EGO59245.1 - 0.09 12.5 0.0 0.15 11.8 0.0 1.5 1 1 0 1 1 1 0 NADPH-dependent FMN reductase ADH_zinc_N PF00107.26 EGO59246.1 - 1.5e-25 89.7 0.1 2.3e-25 89.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO59246.1 - 9.7e-23 81.7 0.0 1.7e-22 80.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO59246.1 - 5.6e-07 29.4 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EGO59246.1 - 0.0021 17.6 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 EGO59246.1 - 0.014 14.8 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MoCF_biosynth PF00994.24 EGO59246.1 - 0.045 13.4 0.1 0.086 12.5 0.1 1.4 1 0 0 1 1 1 0 Probable molybdopterin binding domain MID_MedPIWI PF18296.1 EGO59247.1 - 0.066 13.0 0.1 0.066 13.0 0.1 1.9 2 1 0 2 2 2 0 MID domain of medPIWI GFA PF04828.14 EGO59248.1 - 3.7e-16 59.2 0.6 5.4e-16 58.7 0.6 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Guanylate_kin PF00625.21 EGO59249.1 - 2.5e-59 200.0 0.0 2.8e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 EGO59249.1 - 6.1e-06 26.5 0.0 6.9e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGO59249.1 - 0.00015 22.3 0.1 0.00045 20.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO59249.1 - 0.0031 17.9 0.1 0.0061 16.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGO59249.1 - 0.0088 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EGO59249.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EGO59249.1 - 0.013 15.7 0.0 0.025 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGO59249.1 - 0.021 15.3 0.0 0.026 15.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 EGO59249.1 - 0.037 14.3 0.1 0.42 10.9 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGO59249.1 - 0.038 14.0 0.0 0.13 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGO59249.1 - 0.047 13.4 0.0 3 7.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGO59249.1 - 0.1 13.1 0.2 14 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 EGO59249.1 - 0.11 11.5 0.0 0.76 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_29 PF13555.6 EGO59249.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FMO-like PF00743.19 EGO59251.1 - 3.7e-14 52.1 0.0 1.6e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EGO59251.1 - 1.1e-12 47.7 0.0 9.9e-09 34.8 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EGO59251.1 - 1.6e-10 40.8 0.0 3.7e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO59251.1 - 3.9e-07 29.6 0.0 7.9e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO59251.1 - 2.1e-06 27.8 0.0 6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGO59251.1 - 0.00042 20.3 0.1 0.0093 16.0 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EGO59251.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EGO59251.1 - 0.16 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EGO59251.1 - 0.16 12.5 0.2 3.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GerE PF00196.19 EGO59251.1 - 0.17 11.5 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF3638 PF12340.8 EGO59255.1 - 1.5e-91 305.7 0.2 3.1e-91 304.7 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EGO59255.1 - 5.2e-15 54.5 0.2 1.2e-14 53.4 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) TENA_THI-4 PF03070.16 EGO59257.1 - 3e-07 30.5 0.0 9.2e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 TENA/THI-4/PQQC family TFR_dimer PF04253.15 EGO59262.1 - 6.8e-35 119.8 0.0 1.4e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EGO59262.1 - 5.9e-21 75.1 0.0 1.2e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EGO59262.1 - 1.4e-11 44.3 0.0 2.9e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 PA domain Vps35 PF03635.17 EGO59263.1 - 0 1034.7 0.3 0 1034.5 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ank_2 PF12796.7 EGO59264.1 - 2.8e-34 117.5 0.6 4.6e-07 30.3 0.0 7.5 4 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO59264.1 - 1.1e-20 73.6 6.5 0.01 16.4 0.0 9.3 6 2 4 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO59264.1 - 1.7e-18 66.5 16.7 1.4e-05 25.2 0.0 9.6 7 3 3 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO59264.1 - 3.6e-18 63.8 17.5 0.4 11.4 0.0 12.6 12 0 0 12 12 12 4 Ankyrin repeat Ank PF00023.30 EGO59264.1 - 2.4e-16 59.4 18.8 0.25 11.9 0.0 10.9 10 1 1 11 11 11 5 Ankyrin repeat F-box-like PF12937.7 EGO59264.1 - 0.00028 20.7 0.1 0.00061 19.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO59264.1 - 0.033 14.1 0.3 0.077 12.9 0.3 1.5 1 0 0 1 1 1 0 F-box domain PhoLip_ATPase_C PF16212.5 EGO59265.1 - 6.4e-68 229.2 9.3 1.4e-67 228.0 9.3 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGO59265.1 - 2.7e-23 81.4 2.0 8.1e-23 79.9 0.2 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGO59265.1 - 1.6e-12 47.3 0.0 1.8e-11 43.9 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGO59265.1 - 5.1e-11 43.3 0.1 2e-06 28.3 0.1 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGO59265.1 - 5.2e-09 35.9 1.4 7.9e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGO59265.1 - 0.0013 18.6 0.0 0.006 16.4 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Lipase_GDSL_2 PF13472.6 EGO59267.1 - 7.3e-20 72.1 0.6 1e-19 71.6 0.6 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGO59267.1 - 2.2e-12 47.4 0.0 2.8e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EGO59267.1 - 3.9e-05 23.9 0.2 7.3e-05 23.0 0.0 1.4 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family TFIIB PF00382.19 EGO59269.1 - 1.4e-30 105.2 4.2 9.6e-16 57.6 0.6 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EGO59269.1 - 1.7e-19 70.0 0.7 1.7e-19 70.0 0.7 4.4 3 1 1 4 4 4 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 EGO59269.1 - 0.00037 20.2 1.0 0.75 9.6 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain BTB PF00651.31 EGO59270.1 - 5.1e-05 23.5 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain DUF1345 PF07077.11 EGO59271.1 - 0.26 11.0 3.8 0.25 11.0 1.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF3810 PF12725.7 EGO59271.1 - 0.79 9.0 4.4 3.6 6.9 1.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) Peptidase_S24 PF00717.23 EGO59272.1 - 2.8e-07 30.4 0.0 4.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like HLH PF00010.26 EGO59274.1 - 1.2e-10 41.1 0.1 1.2e-10 41.1 0.1 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain He_PIG PF05345.12 EGO59274.1 - 0.037 14.2 4.2 0.055 13.7 2.6 2.1 2 0 0 2 2 2 0 Putative Ig domain RabGAP-TBC PF00566.18 EGO59277.1 - 5.4e-34 117.7 0.1 5.6e-18 65.4 0.0 3.4 3 0 0 3 3 3 3 Rab-GTPase-TBC domain DNA_pol_phi PF04931.13 EGO59277.1 - 4.4 5.3 7.6 6.8 4.7 7.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi UQ_con PF00179.26 EGO59279.1 - 6.8e-40 136.0 0.0 8e-40 135.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO59279.1 - 0.0023 17.6 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGO59279.1 - 0.025 14.9 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EGO59279.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain TPR_19 PF14559.6 EGO59280.1 - 0.056 13.9 3.9 20 5.8 0.7 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGO59280.1 - 0.076 13.4 0.1 15 6.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGO59280.1 - 0.18 12.7 7.2 6.7 7.8 0.2 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGO59280.1 - 0.22 11.7 2.7 0.94 9.7 1.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGO59280.1 - 0.81 9.4 2.6 1.5 8.6 0.1 2.6 2 0 0 2 2 2 0 TPR repeat ChAPs PF09295.10 EGO59281.1 - 1.1e-155 518.5 0.0 1.4e-155 518.2 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 EGO59281.1 - 2.3e-06 28.0 0.9 0.84 10.6 0.3 5.2 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGO59281.1 - 7.1e-05 22.6 0.4 0.58 10.3 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGO59281.1 - 0.00011 22.2 0.4 0.0094 16.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGO59281.1 - 0.00036 20.5 0.0 0.17 12.2 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGO59281.1 - 0.00081 19.3 0.8 0.33 11.2 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGO59281.1 - 0.0022 18.4 0.9 1.5 9.3 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGO59281.1 - 0.014 16.0 0.1 19 6.2 0.1 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGO59281.1 - 0.02 14.7 0.2 8.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO59281.1 - 0.08 13.2 1.5 20 5.5 0.0 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGO59281.1 - 0.13 12.6 0.4 8.9 6.7 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 EGO59282.1 - 5.2e-49 167.0 0.2 4e-47 160.8 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family TcpQ PF10671.9 EGO59282.1 - 0.022 14.9 0.3 0.049 13.8 0.3 1.5 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q HIT PF01230.23 EGO59283.1 - 5.8e-18 65.4 0.0 9.5e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGO59283.1 - 4.7e-07 30.3 0.0 7.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EGO59283.1 - 0.018 14.9 0.1 0.05 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 DNA_RNApol_7kD PF03604.13 EGO59284.1 - 1.1e-15 57.0 3.8 1.4e-15 56.7 3.8 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 EGO59284.1 - 0.014 15.4 0.3 0.02 14.9 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbon_6 PF10005.9 EGO59284.1 - 0.029 15.0 0.1 0.039 14.6 0.1 1.2 1 0 0 1 1 1 0 zinc-ribbon domain zf-ISL3 PF14690.6 EGO59284.1 - 0.037 14.7 1.4 0.067 13.9 0.1 1.9 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 GFA PF04828.14 EGO59284.1 - 0.066 13.6 0.7 8 6.9 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf_UBZ PF18439.1 EGO59284.1 - 0.087 12.4 0.6 4.2 7.1 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 EGO59284.1 - 0.11 12.5 0.3 0.14 12.2 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ATP_bind_1 PF03029.17 EGO59285.1 - 1.2e-70 238.1 0.0 2.2e-70 237.2 0.0 1.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 EGO59285.1 - 9e-05 21.6 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 EGO59285.1 - 0.00015 21.0 0.0 0.0014 17.9 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 EGO59285.1 - 0.00064 19.8 0.0 0.0015 18.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO59285.1 - 0.0012 18.4 0.0 0.07 12.7 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EGO59285.1 - 0.0014 19.1 0.0 0.003 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EGO59285.1 - 0.0015 17.8 0.9 0.0018 17.5 0.0 1.5 2 0 0 2 2 1 1 NB-ARC domain AAA_24 PF13479.6 EGO59285.1 - 0.002 17.9 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 EGO59285.1 - 0.0046 16.7 0.0 0.013 15.2 0.0 1.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Roc PF08477.13 EGO59285.1 - 0.0048 17.1 0.0 4.4 7.6 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EGO59285.1 - 0.0054 16.5 0.0 0.0091 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 EGO59285.1 - 0.0061 16.1 0.1 0.18 11.4 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_7 PF12775.7 EGO59285.1 - 0.0065 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 EGO59285.1 - 0.007 15.7 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_23 PF13476.6 EGO59285.1 - 0.0075 16.8 0.0 1 9.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGO59285.1 - 0.0076 16.5 0.0 0.023 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO59285.1 - 0.0081 16.3 1.4 0.03 14.5 0.0 2.4 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 EGO59285.1 - 0.013 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Arf PF00025.21 EGO59285.1 - 0.015 14.8 0.0 0.66 9.4 0.0 2.6 3 0 0 3 3 3 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGO59285.1 - 0.028 14.3 0.0 9.8 6.0 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase ATPase_2 PF01637.18 EGO59285.1 - 0.031 14.2 0.1 0.088 12.7 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SRP54 PF00448.22 EGO59285.1 - 0.041 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 EGO59285.1 - 0.085 12.4 0.0 0.73 9.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EGO59285.1 - 0.097 13.2 3.8 0.3 11.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 EGO59285.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGO59285.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Methyltransf_32 PF13679.6 EGO59285.1 - 0.2 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Thymidylate_kin PF02223.17 EGO59285.1 - 0.2 11.3 1.3 0.79 9.4 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase Pox_A32 PF04665.12 EGO59285.1 - 0.21 11.0 0.0 0.64 9.4 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein CDC27 PF09507.10 EGO59285.1 - 2.3 7.5 10.6 3.5 6.9 10.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SASP PF00269.20 EGO59286.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type CwfJ_C_2 PF04676.14 EGO59287.1 - 1.5e-29 102.7 0.1 1.5e-29 102.7 0.1 2.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 EGO59287.1 - 9.5e-25 86.8 0.0 1.9e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 FumaraseC_C PF10415.9 EGO59287.1 - 0.00057 20.3 4.2 0.27 11.7 0.5 2.9 2 0 0 2 2 2 2 Fumarase C C-terminus DEAD PF00270.29 EGO59288.1 - 3.8e-48 163.6 0.0 6.8e-48 162.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO59288.1 - 3.7e-29 101.3 0.1 1.2e-28 99.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO59288.1 - 2.4e-07 30.9 0.0 1.2e-06 28.6 0.0 2.2 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Borrelia_P83 PF05262.11 EGO59288.1 - 0.15 10.6 5.1 0.21 10.1 5.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 EGO59288.1 - 7.8 5.1 6.2 11 4.6 6.2 1.2 1 0 0 1 1 1 0 Presenilin Brix PF04427.18 EGO59289.1 - 1.1e-47 162.7 0.0 1.5e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain PNISR PF15996.5 EGO59289.1 - 9.5 6.4 26.3 8.2 6.6 22.5 2.1 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Glyco_hydro_18 PF00704.28 EGO59293.1 - 4.4e-26 92.4 0.8 2.6e-25 89.8 0.7 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.18 EGO59293.1 - 8.3e-10 38.5 8.6 2.3e-09 37.1 8.6 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain LMF1 PF06762.14 EGO59294.1 - 0.0055 15.9 0.3 0.0077 15.4 0.3 1.1 1 0 0 1 1 1 1 Lipase maturation factor Rubella_Capsid PF05750.11 EGO59294.1 - 0.63 9.6 7.8 0.97 9.0 7.8 1.2 1 0 0 1 1 1 0 Rubella capsid protein TPR_19 PF14559.6 EGO59295.1 - 7e-06 26.5 1.8 0.021 15.3 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGO59295.1 - 0.00064 19.2 0.0 0.004 16.6 0.0 2.0 1 1 1 2 2 2 1 MalT-like TPR region TPR_2 PF07719.17 EGO59295.1 - 0.015 15.4 0.3 41 4.6 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO59295.1 - 0.06 13.6 0.0 0.42 10.9 0.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 EGO59295.1 - 0.13 11.6 0.0 0.28 10.6 0.0 1.5 1 1 0 1 1 1 0 Coatomer epsilon subunit SUR7 PF06687.12 EGO59296.1 - 4.8e-13 49.2 13.4 6e-13 48.9 13.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2975 PF11188.8 EGO59296.1 - 0.032 14.1 4.7 0.063 13.2 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DuoxA PF10204.9 EGO59296.1 - 0.083 11.9 3.0 0.13 11.3 3.0 1.2 1 0 0 1 1 1 0 Dual oxidase maturation factor Clc-like PF07062.12 EGO59296.1 - 0.82 9.1 7.2 1.3 8.5 7.2 1.3 1 0 0 1 1 1 0 Clc-like Cu_bind_like PF02298.17 EGO59297.1 - 2.9e-05 24.0 0.0 5.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 EGO59297.1 - 0.00021 21.7 0.1 0.0004 20.8 0.1 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cyclin_N PF00134.23 EGO59298.1 - 0.00026 20.7 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain PRP38_assoc PF12871.7 EGO59298.1 - 0.0018 18.8 5.1 0.0033 18.0 5.1 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Esterase_phd PF10503.9 EGO59299.1 - 1.2e-16 60.9 0.0 2e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EGO59299.1 - 1.3e-05 24.8 0.1 2.9e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EGO59299.1 - 5.9e-05 22.8 0.1 6.5e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 EGO59299.1 - 0.0096 15.8 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold GPI-anchored PF10342.9 EGO59300.1 - 4.1e-14 53.1 2.3 4.1e-14 53.1 2.3 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Trs65 PF12735.7 EGO59300.1 - 0.061 12.7 1.7 0.073 12.5 1.7 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 Ifi-6-16 PF06140.13 EGO59304.1 - 4.3e-06 26.6 28.2 4.8e-06 26.4 27.3 1.6 1 1 1 2 2 2 1 Interferon-induced 6-16 family ABA_WDS PF02496.16 EGO59304.1 - 5.8 7.5 8.3 0.64 10.5 2.7 2.3 2 1 0 2 2 2 0 ABA/WDS induced protein Ifi-6-16 PF06140.13 EGO59305.1 - 8.9e-05 22.3 26.3 8.9e-05 22.3 26.3 2.0 1 1 1 2 2 2 1 Interferon-induced 6-16 family Ifi-6-16 PF06140.13 EGO59306.1 - 2.4e-06 27.3 30.6 5.2e-06 26.3 30.5 1.7 1 1 0 1 1 1 1 Interferon-induced 6-16 family ApoLp-III PF07464.11 EGO59306.1 - 0.048 13.7 4.5 0.57 10.3 1.6 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) RapH_N PF18801.1 EGO59306.1 - 0.21 11.7 0.2 3.5 7.8 0.0 2.5 2 1 1 3 3 3 0 response regulator aspartate phosphatase H, N terminal BMFP PF04380.13 EGO59306.1 - 0.28 11.7 2.7 10 6.7 0.1 3.5 1 1 3 4 4 4 0 Membrane fusogenic activity DUF883 PF05957.13 EGO59306.1 - 1 10.0 15.4 1.7 9.3 0.8 3.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) TrbI PF03743.14 EGO59306.1 - 1.4 8.7 11.7 1.3 8.8 0.3 2.5 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein Ifi-6-16 PF06140.13 EGO59307.1 - 1.1e-25 89.4 23.7 6.8e-14 51.5 8.0 2.4 2 0 0 2 2 2 2 Interferon-induced 6-16 family AdoHcyase_NAD PF00670.21 EGO59307.1 - 1.2 9.1 4.4 7.1 6.7 0.0 3.0 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ifi-6-16 PF06140.13 EGO59308.1 - 2.6e-11 43.2 4.1 4.8e-11 42.4 4.1 1.5 1 0 0 1 1 1 1 Interferon-induced 6-16 family Ribosomal_L2_C PF03947.18 EGO59309.1 - 0.0049 17.0 5.5 0.27 11.5 1.0 2.7 1 1 1 2 2 2 2 Ribosomal Proteins L2, C-terminal domain DNA_binding_1 PF01035.20 EGO59309.1 - 0.0052 16.9 7.0 0.85 9.8 0.4 3.8 1 1 2 3 3 3 2 6-O-methylguanine DNA methyltransferase, DNA binding domain MTD PF01993.18 EGO59309.1 - 0.22 10.8 2.9 0.31 10.4 2.4 1.4 1 1 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Virulence_fact PF13769.6 EGO59309.1 - 0.28 11.4 2.7 4.9 7.4 0.0 2.4 1 1 1 2 2 2 0 Virulence factor Fst_toxin PF13955.6 EGO59309.1 - 9.9 6.2 8.5 52 3.9 0.4 3.8 3 0 0 3 3 3 0 Toxin Fst, type I toxin-antitoxin system Ifi-6-16 PF06140.13 EGO59310.1 - 3.3e-07 30.1 24.0 4.9e-07 29.6 24.0 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family NUC153 PF08159.12 EGO59311.1 - 1.8e-15 56.4 9.8 3.2e-15 55.6 0.7 3.7 3 0 0 3 3 3 2 NUC153 domain P5-ATPase PF12409.8 EGO59311.1 - 0.24 11.5 2.3 0.98 9.5 0.1 2.9 2 0 0 2 2 2 0 P5-type ATPase cation transporter Kre28 PF17097.5 EGO59312.1 - 0.0066 15.4 0.0 0.0066 15.4 0.0 1.4 2 0 0 2 2 2 1 Spindle pole body component EST1 PF10374.9 EGO59312.1 - 0.069 13.8 0.1 0.069 13.8 0.1 2.4 3 1 0 3 3 3 0 Telomerase activating protein Est1 FBPase PF00316.20 EGO59313.1 - 4.5e-23 81.7 0.0 1.3e-22 80.2 0.0 1.6 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Hce2 PF14856.6 EGO59315.1 - 1.5e-26 92.6 0.3 2.9e-26 91.7 0.3 1.5 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor AFG1_ATPase PF03969.16 EGO59316.1 - 1.2e-96 323.8 0.0 2.7e-92 309.5 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EGO59316.1 - 1.7e-05 25.3 0.8 0.058 13.8 0.0 3.4 3 1 1 4 4 4 2 AAA ATPase domain Bac_DnaA PF00308.18 EGO59316.1 - 3.8e-05 23.7 0.3 0.03 14.2 0.0 2.7 2 1 0 2 2 2 2 Bacterial dnaA protein AAA PF00004.29 EGO59316.1 - 0.00072 20.0 0.0 0.011 16.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGO59316.1 - 0.00079 19.5 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGO59316.1 - 0.0013 19.0 0.0 0.016 15.5 0.0 2.6 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.14 EGO59316.1 - 0.0042 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGO59316.1 - 0.0045 17.4 0.3 0.041 14.3 0.1 2.6 2 1 0 2 2 2 1 RNA helicase TsaE PF02367.17 EGO59316.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE UvrD-helicase PF00580.21 EGO59316.1 - 0.09 12.3 0.0 0.18 11.3 0.0 1.4 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain NACHT PF05729.12 EGO59316.1 - 0.12 12.3 0.0 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 EGO59316.1 - 0.16 12.5 0.0 6.9 7.2 0.0 2.8 3 0 0 3 3 3 0 ABC transporter ATPase_2 PF01637.18 EGO59316.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF1295 PF06966.12 EGO59317.1 - 8.7e-15 54.9 0.2 1.2e-14 54.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 EGO59317.1 - 1.2e-06 27.6 1.1 1.2e-06 27.6 1.1 1.5 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 EGO59317.1 - 1.9e-05 24.7 0.1 2.9e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 EGO59317.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Presenilin PF01080.17 EGO59317.1 - 0.15 10.8 8.1 0.13 11.0 3.8 2.1 2 0 0 2 2 2 0 Presenilin Apt1 PF10351.9 EGO59317.1 - 0.68 8.7 4.7 0.87 8.4 4.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 EGO59317.1 - 2.1 5.4 3.6 2.6 5.0 3.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SelP_N PF04592.14 EGO59317.1 - 4.5 6.6 6.2 6.8 6.0 6.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_M28 PF04389.17 EGO59318.1 - 9.5e-30 103.8 0.1 1.5e-29 103.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGO59318.1 - 4e-07 30.0 0.1 7.8e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 DUF999 PF06198.11 EGO59318.1 - 0.033 14.2 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF999) PLDc_2 PF13091.6 EGO59319.1 - 1.5e-18 66.9 0.2 6.3e-12 45.5 0.0 3.1 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EGO59319.1 - 5.4e-05 23.2 3.1 0.081 13.1 0.0 3.8 4 0 0 4 4 4 2 Phospholipase D Active site motif DUF3632 PF12311.8 EGO59320.1 - 2.9e-10 40.9 6.3 1.4e-05 25.6 2.9 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3632) CaMBD PF02888.16 EGO59320.1 - 0.079 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Calmodulin binding domain Palm_thioest PF02089.15 EGO59322.1 - 0.054 13.3 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGO59322.1 - 0.11 12.2 0.0 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein LIP PF03583.14 EGO59322.1 - 0.12 11.7 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Secretory lipase Oxidored_molyb PF00174.19 EGO59323.1 - 1.2e-48 165.0 0.0 5.8e-48 162.8 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGO59323.1 - 3.9e-22 78.8 1.1 7.2e-22 77.9 1.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain CAP59_mtransfer PF11735.8 EGO59324.1 - 2e-85 286.4 0.0 2.5e-85 286.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DEAD PF00270.29 EGO59325.1 - 3.7e-17 62.7 0.0 6.5e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGO59325.1 - 2.1e-11 44.1 0.0 5.8e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGO59325.1 - 3.1e-07 30.7 0.0 7.2e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.16 EGO59325.1 - 0.016 14.7 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Lentivirus_VIF PF05851.11 EGO59325.1 - 0.13 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) CAP PF00188.26 EGO59326.1 - 1.3e-20 74.5 2.7 2e-20 73.9 2.7 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family HD_3 PF13023.6 EGO59327.1 - 1.8e-51 174.4 0.3 2.5e-51 173.9 0.3 1.2 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EGO59327.1 - 1.5e-12 47.7 0.1 2e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EGO59327.1 - 0.0064 16.7 0.0 0.019 15.2 0.0 1.8 1 1 0 1 1 1 1 HD domain AA_permease PF00324.21 EGO59329.1 - 1.4e-104 350.4 39.2 1.7e-104 350.1 39.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO59329.1 - 4.9e-27 94.8 41.1 6.1e-27 94.5 41.1 1.0 1 0 0 1 1 1 1 Amino acid permease HD PF01966.22 EGO59331.1 - 6.5e-06 26.4 0.0 1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 HD domain SelB-wing_2 PF09106.11 EGO59332.1 - 0.0077 16.4 0.1 0.019 15.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor SelB, winged helix PKD_channel PF08016.12 EGO59332.1 - 0.1 11.3 1.8 1 7.9 0.1 2.2 2 0 0 2 2 2 0 Polycystin cation channel DUF4834 PF16118.5 EGO59334.1 - 7.5 7.6 0.0 7.5 7.6 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Nucleoporin_N PF08801.11 EGO59335.1 - 1.1e-104 350.6 0.0 1.6e-104 350.1 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EGO59335.1 - 1.7e-45 155.9 2.2 2.9e-45 155.1 1.3 1.8 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal adh_short PF00106.25 EGO59336.1 - 1.2e-38 132.5 0.0 1.6e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO59336.1 - 3.7e-23 82.3 0.0 4.9e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO59336.1 - 2.7e-08 34.0 0.0 6.7e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EGO59336.1 - 0.0025 18.1 0.0 0.044 14.0 0.0 2.7 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EGO59336.1 - 0.028 14.3 0.0 0.065 13.1 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGO59336.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GalP_UDP_transf PF01087.22 EGO59337.1 - 1.9e-70 237.1 0.4 1.4e-69 234.2 0.2 2.0 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EGO59337.1 - 5.8e-61 205.1 0.1 1.2e-60 204.1 0.1 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 EGO59337.1 - 0.00025 21.7 0.0 0.0084 16.8 0.0 2.4 2 1 0 2 2 2 1 HIT domain HTH_ParB PF17762.1 EGO59337.1 - 0.077 12.8 0.2 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 HTH domain found in ParB protein Myb_DNA-binding PF00249.31 EGO59338.1 - 2.1e-10 40.6 0.0 6.3e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EGO59338.1 - 4.8e-09 35.9 5.3 9.2e-09 35.0 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 EGO59338.1 - 1.1e-06 28.8 0.0 4e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain SHOCT PF09851.9 EGO59338.1 - 0.03 14.1 0.6 0.1 12.3 0.6 2.0 1 0 0 1 1 1 0 Short C-terminal domain Mg_trans_NIPA PF05653.14 EGO59339.1 - 2.6e-88 295.9 28.3 3.4e-88 295.6 28.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EGO59339.1 - 0.0026 18.0 7.9 0.0026 18.0 7.9 3.4 3 0 0 3 3 3 2 EamA-like transporter family DUF5362 PF17319.2 EGO59339.1 - 0.072 12.9 0.1 0.072 12.9 0.1 3.1 3 1 0 3 3 3 0 Family of unknown function (DUF5362) Deltameth_res PF16020.5 EGO59339.1 - 6.1 6.8 9.0 0.3 11.0 0.2 3.4 3 1 1 4 4 4 0 Deltamethrin resistance U-box PF04564.15 EGO59340.1 - 2.1e-19 69.5 0.1 3.9e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 EGO59340.1 - 4.5e-08 32.6 2.6 0.004 16.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGO59340.1 - 5.8e-07 29.1 2.9 0.14 12.4 0.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGO59340.1 - 0.0022 18.2 6.6 0.74 10.2 0.2 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 EGO59340.1 - 0.0034 18.1 14.1 0.0066 17.2 14.1 1.5 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_8 PF13181.6 EGO59340.1 - 0.0058 16.8 1.3 7.7 7.0 0.1 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO59340.1 - 0.0068 16.4 0.6 13 6.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TetR_C_11 PF16859.5 EGO59340.1 - 0.046 14.0 0.0 0.09 13.1 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Dehydrin PF00257.19 EGO59340.1 - 0.077 13.5 0.0 0.087 13.4 0.0 1.3 1 0 0 1 1 1 0 Dehydrin TPR_11 PF13414.6 EGO59340.1 - 0.95 9.2 3.9 17 5.2 0.2 3.0 3 0 0 3 3 3 0 TPR repeat DUF883 PF05957.13 EGO59340.1 - 1.1 9.9 5.4 0.52 10.9 2.0 2.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) RRF PF01765.19 EGO59340.1 - 2.3 8.1 6.4 3.7 7.5 6.4 1.3 1 0 0 1 1 1 0 Ribosome recycling factor SH3_9 PF14604.6 EGO59341.1 - 4.9e-10 39.1 0.0 8e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGO59341.1 - 1.9e-05 24.2 0.0 2.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGO59341.1 - 0.0001 21.9 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Protocadherin PF08374.11 EGO59341.1 - 0.059 13.3 0.0 0.059 13.3 0.0 1.7 2 0 0 2 2 2 0 Protocadherin Cytokin-bind PF09265.10 EGO59341.1 - 0.14 11.5 0.5 0.2 11.0 0.5 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Glycophorin_A PF01102.18 EGO59341.1 - 0.18 12.1 2.9 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 Glycophorin A DUF1576 PF07613.11 EGO59341.1 - 0.32 10.5 1.6 0.5 9.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) Gar1 PF04410.14 EGO59342.1 - 2.1e-45 154.2 3.1 2.1e-45 154.2 3.1 2.2 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Glyco_transf_22 PF03901.17 EGO59343.1 - 2.2e-85 287.4 17.9 2.6e-85 287.2 17.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HET PF06985.11 EGO59344.1 - 1e-24 87.6 0.0 2.4e-24 86.3 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Oxidored_FMN PF00724.20 EGO59345.1 - 8.9e-98 327.7 0.0 1e-97 327.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 EGO59345.1 - 0.065 12.7 0.0 3.4 7.0 0.0 2.6 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel F-box-like PF12937.7 EGO59346.1 - 0.017 15.0 0.0 0.18 11.7 0.0 2.3 1 1 0 1 1 1 0 F-box-like F-box PF00646.33 EGO59346.1 - 0.068 13.1 0.3 17 5.4 0.1 2.4 2 0 0 2 2 2 0 F-box domain ProRS-C_1 PF09180.11 EGO59348.1 - 8.1e-23 80.4 0.2 1.7e-22 79.4 0.2 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EGO59348.1 - 1.9e-20 73.6 0.0 3.6e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGO59348.1 - 1e-17 64.0 0.0 2.3e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain DnaB_2 PF07261.11 EGO59348.1 - 0.012 15.4 0.5 0.029 14.1 0.5 1.6 1 0 0 1 1 1 0 Replication initiation and membrane attachment HK97-gp10_like PF04883.12 EGO59348.1 - 0.81 10.7 4.5 2.4 9.2 2.0 2.7 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Cpn60_TCP1 PF00118.24 EGO59349.1 - 4.5e-151 503.8 17.4 5.1e-151 503.6 17.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MFS_1 PF07690.16 EGO59351.1 - 1.1e-27 96.9 66.7 5.1e-18 65.1 38.9 2.4 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 EGO59351.1 - 7.3e-11 41.3 17.8 1.3e-10 40.4 7.1 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Nucleoporin_FG2 PF15967.5 EGO59351.1 - 3.4 6.1 4.8 1.3 7.4 2.0 1.6 2 0 0 2 2 2 0 Nucleoporin FG repeated region SNF2_N PF00176.23 EGO59352.1 - 2.7e-40 138.2 0.1 4.6e-39 134.1 0.1 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO59352.1 - 2.5e-12 47.1 0.0 1.4e-11 44.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO59352.1 - 4.4e-10 39.8 0.1 3.8e-09 36.8 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGO59352.1 - 3.2e-06 26.5 0.0 6.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 EGO59352.1 - 5.3e-05 23.0 0.1 0.00018 21.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase TEX33 PF15400.6 EGO59352.1 - 0.0006 20.3 0.0 0.0018 18.8 0.0 1.8 1 0 0 1 1 1 1 Testis-expressed sequence 33 protein family zf-RING_5 PF14634.6 EGO59352.1 - 0.1 12.6 6.0 0.19 11.7 6.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO59352.1 - 0.18 11.7 3.8 0.39 10.6 3.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO59352.1 - 0.37 11.2 5.9 0.79 10.1 5.9 1.5 1 0 0 1 1 1 0 Ring finger domain Ank_2 PF12796.7 EGO59353.1 - 3.3e-41 139.8 17.4 5.3e-07 30.1 0.2 14.7 11 3 3 14 14 14 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO59353.1 - 1.4e-21 76.5 15.1 0.071 13.7 0.0 14.2 10 5 5 15 15 15 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO59353.1 - 2e-20 70.7 16.3 0.0058 17.0 0.0 17.1 19 0 0 19 19 19 4 Ankyrin repeat Ank_5 PF13857.6 EGO59353.1 - 3.4e-12 46.3 16.5 5.7e-06 26.5 0.0 11.4 12 1 1 13 13 13 2 Ankyrin repeats (many copies) Ank PF00023.30 EGO59353.1 - 6.2e-12 45.4 34.9 0.0035 17.7 0.1 14.5 16 1 1 17 17 17 4 Ankyrin repeat HTH_16 PF12645.7 EGO59353.1 - 0.18 11.9 0.4 0.81 9.8 0.2 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain ADH_zinc_N PF00107.26 EGO59354.1 - 5.8e-26 91.0 0.1 9e-26 90.4 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO59354.1 - 8.1e-21 75.5 0.1 1.4e-20 74.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EGO59354.1 - 1.6e-07 31.2 0.0 3.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_N PF08240.12 EGO59354.1 - 7.6e-05 22.5 0.0 0.00022 21.1 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 EGO59355.1 - 4.6e-48 163.8 0.0 5.7e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO59355.1 - 4e-45 154.6 0.0 7.2e-45 153.8 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGO59355.1 - 1.1e-14 54.2 0.0 3.1e-14 52.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGO59355.1 - 4.6e-13 49.0 0.0 4.3e-11 42.5 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGO59355.1 - 4.7e-12 45.6 0.0 6.7e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EGO59355.1 - 4.5e-09 36.1 0.0 6.9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EGO59355.1 - 6.4e-07 28.8 0.0 4.7e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EGO59355.1 - 1.2e-06 28.5 0.0 2.2e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGO59355.1 - 0.00032 20.7 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 EGO59355.1 - 0.009 15.6 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 EGO59355.1 - 0.021 14.4 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 EGO59355.1 - 0.1 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sad1_UNC PF07738.13 EGO59357.1 - 2.3e-11 43.9 0.0 1.7e-05 24.8 0.0 2.4 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal DEAD PF00270.29 EGO59358.1 - 1.3e-46 158.5 0.0 2.5e-46 157.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO59358.1 - 3.7e-24 85.2 0.0 1.7e-23 83.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGO59358.1 - 1.3e-21 76.5 0.0 3.6e-21 75.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGO59358.1 - 5.6e-07 29.7 1.3 2.2e-06 27.8 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit IBR PF01485.21 EGO59359.1 - 1.1e-12 48.0 1.8 1.1e-12 48.0 1.8 3.7 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain DNA_ligase_ZBD PF03119.16 EGO59359.1 - 0.0097 15.9 7.5 6 7.0 0.1 3.9 3 0 0 3 3 3 2 NAD-dependent DNA ligase C4 zinc finger domain CpXC PF14353.6 EGO59359.1 - 0.02 14.9 3.7 0.3 11.2 0.0 2.7 2 1 0 2 2 2 0 CpXC protein zinc-ribbons_6 PF07191.12 EGO59359.1 - 0.045 13.7 13.5 1.7 8.7 0.3 3.5 2 1 1 3 3 3 0 zinc-ribbons DUF555 PF04475.12 EGO59359.1 - 0.13 12.6 1.4 9.3 6.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF555) OrfB_Zn_ribbon PF07282.11 EGO59359.1 - 0.55 10.2 16.8 0.7 9.9 0.3 3.6 3 1 0 3 3 3 0 Putative transposase DNA-binding domain zf-RING_14 PF17978.1 EGO59359.1 - 1.7 9.1 9.2 0.77 10.2 5.8 2.2 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain BTB PF00651.31 EGO59361.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain AA_permease PF00324.21 EGO59363.1 - 7e-125 417.3 31.4 8.4e-125 417.1 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO59363.1 - 2.7e-29 102.3 35.3 3.2e-29 102.0 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease Sulfate_transp PF00916.20 EGO59365.1 - 4.2e-124 414.2 15.1 5.2e-124 413.9 15.1 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGO59365.1 - 4.4e-09 36.0 0.0 8.8e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EGO59365.1 - 4.9e-05 23.7 4.0 4.9e-05 23.7 4.0 2.8 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily Ni_hydr_CYTB PF01292.20 EGO59365.1 - 4.4 6.9 11.3 11 5.6 3.5 3.7 2 1 1 3 3 3 0 Prokaryotic cytochrome b561 Peptidase_M15_3 PF08291.11 EGO59366.1 - 0.097 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase M15 PAM2 PF07145.15 EGO59367.1 - 9.8e-06 24.9 0.2 2.1e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Glyco_hydro_16 PF00722.21 EGO59368.1 - 1e-17 64.2 0.2 2.7e-17 62.8 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EGO59368.1 - 1.5e-10 40.1 0.4 0.00017 20.1 0.0 2.0 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Big_3_4 PF13754.6 EGO59368.1 - 0.17 11.6 0.5 0.31 10.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function Peptidase_M28 PF04389.17 EGO59369.1 - 1.7e-43 148.6 0.1 2.5e-43 148.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EGO59369.1 - 1.3e-15 57.2 1.0 3.8e-15 55.7 1.0 1.9 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EGO59369.1 - 2.7e-06 27.2 0.1 1e-05 25.4 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 FokI_C PF02980.16 EGO59369.1 - 0.074 13.1 0.0 0.6 10.1 0.0 2.2 2 0 0 2 2 2 0 Restriction endonuclease FokI, catalytic domain Tam41_Mmp37 PF09139.11 EGO59370.1 - 1.2e-125 419.3 0.0 1.8e-125 418.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial MAD PF05557.13 EGO59371.1 - 2.3e-58 198.1 63.5 2.5e-57 194.7 61.2 2.0 1 1 1 2 2 2 2 Mitotic checkpoint protein muHD PF10291.9 EGO59372.1 - 3.2e-84 282.5 0.0 5e-84 281.9 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 EGO59372.1 - 3.5e-06 27.2 1.9 7e-06 26.2 0.0 2.4 2 1 1 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Muted PF14942.6 EGO59372.1 - 6.9 7.0 10.1 2.6 8.4 6.7 2.0 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Pkinase PF00069.25 EGO59373.1 - 7e-32 110.8 0.0 8.7e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO59373.1 - 6.8e-10 38.7 0.0 9.7e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO59373.1 - 0.0021 16.9 0.0 0.0033 16.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGO59373.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like bZIP_2 PF07716.15 EGO59374.1 - 1.1 9.4 5.1 2.3 8.3 5.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper zf-C2H2 PF00096.26 EGO59375.1 - 0.01 16.3 5.5 0.5 10.9 0.4 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type DNA_pol_phi PF04931.13 EGO59375.1 - 0.37 8.9 7.9 0.51 8.4 7.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Annexin PF00191.20 EGO59376.1 - 1.2e-67 223.8 4.5 6.5e-19 67.8 0.0 4.2 4 0 0 4 4 4 4 Annexin LPAM_1 PF08139.12 EGO59378.1 - 0.42 11.2 1.6 1.4 9.6 1.6 1.9 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site PAP1 PF08601.10 EGO59378.1 - 2.8 7.6 20.3 3.7 7.2 20.3 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 2OG-FeII_Oxy PF03171.20 EGO59380.1 - 1.5e-16 60.7 0.0 3.1e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EGO59380.1 - 4.3e-16 59.7 0.0 7.4e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.16 EGO59381.1 - 3.7e-44 151.1 50.4 1.1e-42 146.2 49.2 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily CD225 PF04505.12 EGO59381.1 - 3.1 8.0 0.0 3.1 8.0 0.0 5.3 5 0 0 5 5 5 0 Interferon-induced transmembrane protein RRM_1 PF00076.22 EGO59382.1 - 0.00069 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Clr5 PF14420.6 EGO59383.1 - 1.9e-19 69.7 2.9 4e-19 68.6 2.9 1.6 1 0 0 1 1 1 1 Clr5 domain RRN9 PF10680.9 EGO59383.1 - 0.015 15.6 0.5 0.043 14.1 0.5 1.8 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Ish1 PF10281.9 EGO59384.1 - 8.2e-99 323.6 14.2 1.3e-15 57.4 0.0 8.3 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.27 EGO59384.1 - 1.1e-12 47.4 0.0 0.068 12.9 0.0 7.3 8 0 0 8 8 8 4 SAP domain Slx4 PF09494.10 EGO59384.1 - 2.4e-09 37.0 1.8 0.59 10.1 0.1 6.3 6 1 0 6 6 6 3 Slx4 endonuclease HeH PF12949.7 EGO59384.1 - 1.9e-06 27.5 0.0 1.8 8.4 0.0 5.4 6 0 0 6 6 6 2 HeH/LEM domain DUF3612 PF12268.8 EGO59384.1 - 0.0059 16.7 0.0 27 4.8 0.0 4.2 4 1 1 5 5 5 0 Protein of unknown function (DUF3612) TilS PF09179.11 EGO59384.1 - 0.016 15.7 4.0 31 5.1 0.0 5.1 5 0 0 5 5 5 0 TilS substrate binding domain SAM_2 PF07647.17 EGO59384.1 - 0.19 11.8 0.4 10 6.3 0.1 3.4 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) EutB PF06751.11 EGO59384.1 - 0.25 10.1 1.2 10 4.8 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine ammonia lyase large subunit (EutB) AAA PF00004.29 EGO59385.1 - 3.9e-40 137.3 0.0 8.8e-40 136.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGO59385.1 - 2.7e-19 68.8 0.1 5.5e-19 67.9 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGO59385.1 - 4.9e-07 29.5 0.0 1.2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGO59385.1 - 0.00024 21.5 1.8 0.021 15.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EGO59385.1 - 0.00032 20.7 0.1 0.0017 18.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGO59385.1 - 0.00033 20.4 0.0 0.00074 19.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGO59385.1 - 0.0017 18.5 0.0 0.011 15.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGO59385.1 - 0.002 18.4 2.0 0.08 13.2 0.0 2.8 2 1 1 3 3 3 1 AAA domain PhoH PF02562.16 EGO59385.1 - 0.0028 17.1 0.3 0.08 12.4 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 EGO59385.1 - 0.0085 15.5 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGO59385.1 - 0.012 15.7 0.0 0.034 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EGO59385.1 - 0.016 14.3 0.0 0.037 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EGO59385.1 - 0.076 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EGO59385.1 - 0.1 12.3 0.9 0.26 11.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGO59385.1 - 0.14 11.7 0.0 0.34 10.4 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 EGO59385.1 - 0.61 9.8 0.0 0.61 9.8 0.0 2.8 2 1 0 3 3 2 0 AAA domain Ribosomal_L10 PF00466.20 EGO59387.1 - 0.0015 18.7 0.0 0.22 11.6 0.0 2.9 1 1 0 1 1 1 1 Ribosomal protein L10 tRNA_lig_CPD PF08302.11 EGO59388.1 - 6.1e-89 297.8 0.0 8.7e-89 297.3 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 EGO59388.1 - 1.7e-86 289.6 0.0 4e-86 288.4 0.0 1.7 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 EGO59388.1 - 8.4e-63 211.4 0.2 8e-62 208.2 0.0 2.2 2 0 0 2 2 2 1 tRNA ligase kinase domain RNA_ligase PF09414.10 EGO59388.1 - 0.019 15.3 0.0 0.075 13.3 0.0 2.1 2 0 0 2 2 2 0 RNA ligase Ank_5 PF13857.6 EGO59389.1 - 1.4e-08 34.8 0.1 7.7e-07 29.3 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGO59389.1 - 7.9e-06 26.3 0.0 8.2e-05 23.1 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO59389.1 - 1.3e-05 25.7 0.1 0.00025 21.6 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO59389.1 - 0.015 15.7 0.0 0.21 12.3 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat Nif11 PF07862.11 EGO59389.1 - 0.097 13.0 1.1 10 6.5 0.1 3.0 3 0 0 3 3 3 0 Nif11 domain Ribonuc_P_40 PF08584.11 EGO59390.1 - 2.2e-43 148.6 0.0 5.1e-43 147.4 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit UPF0020 PF01170.18 EGO59391.1 - 6.8e-08 32.4 0.1 0.00018 21.3 0.0 2.2 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Chorion_2 PF03964.15 EGO59391.1 - 0.0063 17.3 1.2 0.024 15.4 1.1 1.9 2 0 0 2 2 2 1 Chorion family 2 SR-25 PF10500.9 EGO59391.1 - 9.6 5.7 16.5 16 5.0 16.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Vac_ImportDeg PF09783.9 EGO59392.1 - 7.9e-68 227.4 0.6 1.1e-67 226.9 0.6 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.14 EGO59393.1 - 4.5e-70 234.3 0.2 5.1e-70 234.1 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.20 EGO59394.1 - 4.4e-98 329.1 2.2 7.5e-98 328.3 2.2 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 EGO59394.1 - 2e-58 196.2 0.4 4.2e-58 195.2 0.4 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 EGO59394.1 - 5e-56 188.2 0.0 1.4e-55 186.7 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 EGO59394.1 - 1.5e-10 41.4 4.0 2.2e-08 34.3 0.0 3.5 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGO59394.1 - 0.00018 21.8 5.7 0.016 15.6 0.0 4.7 3 1 2 6 6 6 2 HEAT repeats AP4E_app_platf PF14807.6 EGO59394.1 - 0.031 14.6 0.2 0.11 12.9 0.2 2.0 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform HEAT PF02985.22 EGO59394.1 - 0.043 14.1 1.2 2.5 8.6 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat RNA_pol_Rpb4 PF03874.16 EGO59394.1 - 0.062 13.6 0.5 0.5 10.7 0.2 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb4 UBD PF16455.5 EGO59395.1 - 2.2e-30 105.0 1.6 2e-15 56.9 0.5 2.5 3 0 0 3 3 3 2 Ubiquitin-binding domain ubiquitin PF00240.23 EGO59395.1 - 3.9e-06 26.5 0.1 9.9e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EGO59395.1 - 0.00025 21.6 3.1 0.0011 19.5 0.1 2.4 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 EGO59395.1 - 0.00074 19.3 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EGO59395.1 - 0.033 14.3 0.1 0.033 14.3 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Hid1 PF12722.7 EGO59395.1 - 1.3 7.1 4.9 2 6.4 4.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NAD_binding_11 PF14833.6 EGO59396.1 - 3.7e-37 127.3 2.6 6.9e-26 90.9 0.1 2.9 2 1 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EGO59396.1 - 1.1e-31 110.2 0.0 2e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase SET PF00856.28 EGO59396.1 - 5.1e-19 69.3 0.0 4.4e-17 63.0 0.0 2.7 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 EGO59396.1 - 1.7e-18 67.3 6.7 3.7e-18 66.2 4.9 2.2 2 0 0 2 2 2 1 Pre-SET motif 3HCDH_N PF02737.18 EGO59396.1 - 0.001 19.0 0.0 0.0032 17.4 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGO59396.1 - 0.0017 18.9 0.0 0.0077 16.8 0.0 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EGO59396.1 - 0.045 13.4 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F_bP_aldolase PF01116.20 EGO59397.1 - 8.4e-87 291.2 0.1 9.4e-87 291.0 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Dak1 PF02733.17 EGO59398.1 - 7.5e-101 337.1 0.0 1.1e-100 336.6 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EGO59398.1 - 3e-41 141.2 1.8 5.6e-41 140.3 1.8 1.5 1 0 0 1 1 1 1 DAK2 domain LacAB_rpiB PF02502.18 EGO59399.1 - 4.1e-45 153.2 0.6 4.8e-45 153.0 0.6 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase HCMV_UL124 PF17609.2 EGO59399.1 - 0.083 13.1 0.3 2.2 8.5 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function KptA_kDCL PF18176.1 EGO59399.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain TIM PF00121.18 EGO59400.1 - 1.4e-45 155.5 0.0 1.9e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase NmrA PF05368.13 EGO59401.1 - 1.1e-07 31.6 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO59401.1 - 1.8e-05 24.7 0.0 3.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Herpes_ICP4_C PF03585.14 EGO59401.1 - 0.13 10.9 0.0 3.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus ICP4-like protein C-terminal region DUF3618 PF12277.8 EGO59402.1 - 0.052 13.8 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) HSP70 PF00012.20 EGO59403.1 - 6.8e-14 51.0 0.1 2.2e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EGO59403.1 - 0.00011 21.1 0.1 0.0061 15.4 0.2 2.8 2 1 0 2 2 2 1 MreB/Mbl protein NLRC4_HD PF17889.1 EGO59403.1 - 0.18 12.1 0.1 0.45 10.9 0.1 1.6 1 0 0 1 1 1 0 NLRC4 helical domain Glyco_hydro_30 PF02055.16 EGO59404.1 - 6.2e-40 137.2 1.4 8.3e-40 136.8 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 EGO59404.1 - 4.8e-07 29.3 0.4 7.2e-07 28.7 0.4 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 DUF3050 PF11251.8 EGO59404.1 - 0.00017 21.3 0.0 0.00034 20.3 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3050) Glyco_hydr_30_2 PF14587.6 EGO59404.1 - 0.0006 19.5 0.0 0.002 17.8 0.0 1.7 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 EGO59404.1 - 0.0013 18.9 0.1 0.0029 17.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain 3HCDH_N PF02737.18 EGO59406.1 - 1.6e-27 96.5 0.0 2e-26 93.0 0.0 2.1 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EGO59406.1 - 1.8e-15 57.3 0.0 3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 EGO59406.1 - 0.0019 17.6 0.0 0.0047 16.3 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EGO59406.1 - 0.092 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO59406.1 - 0.15 12.6 0.0 0.28 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EGO59406.1 - 0.17 11.5 0.0 0.33 10.5 0.0 1.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 EGO59406.1 - 0.19 11.4 0.3 7.2 6.2 0.1 2.9 3 2 0 3 3 3 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 EGO59406.1 - 0.19 11.7 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SLATT_fungal PF18142.1 EGO59407.1 - 3.3e-30 104.5 0.7 5.3e-30 103.9 0.7 1.3 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Trp_oprn_chp PF09534.10 EGO59407.1 - 0.035 13.9 0.2 0.071 12.9 0.2 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Phage_holin_3_6 PF07332.11 EGO59407.1 - 0.075 13.1 1.2 0.13 12.3 1.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MFS_1 PF07690.16 EGO59408.1 - 6.2e-38 130.6 60.4 3.3e-36 125.0 57.7 3.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGO59408.1 - 5.6e-11 41.6 21.8 8.5e-11 41.0 21.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGO59408.1 - 1.8e-09 37.0 37.6 9.7e-09 34.6 17.0 3.2 2 1 2 4 4 4 2 Sugar (and other) transporter Fungal_trans PF04082.18 EGO59409.1 - 2.5e-14 52.9 0.0 4.1e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO59409.1 - 1.4e-09 37.9 10.4 2.7e-09 37.0 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 EGO59410.1 - 1.4e-07 31.3 8.6 3e-07 30.2 8.6 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 EGO59410.1 - 0.00013 22.4 0.1 0.0013 19.1 0.1 2.6 1 1 0 1 1 1 1 SET domain EB_dh PF09459.10 EGO59411.1 - 0.14 12.1 0.0 0.15 12.0 0.0 1.0 1 0 0 1 1 1 0 Ethylbenzene dehydrogenase E1_DerP2_DerF2 PF02221.15 EGO59412.1 - 4.7e-30 104.7 0.3 5.7e-30 104.5 0.3 1.1 1 0 0 1 1 1 1 ML domain Alph_Pro_TM PF09608.10 EGO59412.1 - 0.097 12.5 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DUF2418 PF10332.9 EGO59413.1 - 2.8e-34 117.5 0.9 7.1e-34 116.2 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Cmyb_C PF09316.10 EGO59413.1 - 0.19 11.4 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 C-myb, C-terminal Aconitase PF00330.20 EGO59414.1 - 2.3e-163 544.5 0.0 3.2e-163 544.0 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGO59414.1 - 2e-40 138.2 0.0 3.5e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain F-box PF00646.33 EGO59416.1 - 0.00011 22.0 0.1 0.00027 20.7 0.1 1.6 1 0 0 1 1 1 1 F-box domain DUF4618 PF15397.6 EGO59416.1 - 0.029 13.8 1.3 0.07 12.5 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) F-box-like PF12937.7 EGO59416.1 - 0.047 13.6 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 F-box-like APG6_N PF17675.1 EGO59416.1 - 0.092 13.3 6.0 0.32 11.5 6.0 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region Rootletin PF15035.6 EGO59416.1 - 0.48 10.4 4.1 0.19 11.7 1.3 1.8 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Transglut_core PF01841.19 EGO59417.1 - 1.6e-10 41.5 0.0 2.9e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily CzcE PF16986.5 EGO59417.1 - 0.041 14.2 0.0 0.083 13.2 0.0 1.4 1 0 0 1 1 1 0 Heavy-metal resistance protein CzcE Gln_amidase PF15644.6 EGO59417.1 - 0.16 13.0 0.0 0.33 12.0 0.0 1.6 1 0 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase Methyltransf_16 PF10294.9 EGO59418.1 - 8.5e-13 48.4 0.0 1.6e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase AMP-binding PF00501.28 EGO59419.1 - 6.9e-90 301.6 0.0 1e-89 301.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO59419.1 - 0.0017 19.3 0.1 0.0049 17.8 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EF-hand_7 PF13499.6 EGO59420.1 - 3.7e-24 85.0 8.3 1.1e-15 57.8 1.0 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EGO59420.1 - 3.8e-24 82.4 10.6 3.5e-08 32.4 0.2 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 EGO59420.1 - 1.3e-23 80.8 5.2 6.5e-07 28.8 0.1 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 EGO59420.1 - 1.1e-16 59.5 10.8 6.6e-05 22.2 0.3 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 EGO59420.1 - 1.4e-14 53.6 11.6 8.7e-06 25.5 0.8 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EGO59420.1 - 2.4e-08 33.9 6.4 0.0052 16.7 0.1 3.8 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGO59420.1 - 4.5e-05 23.7 0.8 0.0013 19.0 0.1 2.7 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EGO59420.1 - 0.0014 18.9 3.0 1.8 8.9 0.4 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EGO59420.1 - 0.016 15.0 0.3 1.3 8.9 0.1 3.1 3 0 0 3 3 3 0 EF hand Staphylokinase PF02821.16 EGO59420.1 - 0.056 13.9 0.1 4.4 7.8 0.1 2.5 1 1 0 1 1 1 0 Staphylokinase/Streptokinase family Caleosin PF05042.13 EGO59420.1 - 0.23 11.4 2.8 16 5.4 0.0 3.3 2 1 2 4 4 4 0 Caleosin related protein CDC45 PF02724.14 EGO59421.1 - 2.9e-252 838.6 10.9 2.6e-229 762.7 0.0 3.1 1 1 2 3 3 3 2 CDC45-like protein BUD22 PF09073.10 EGO59421.1 - 1.4 8.2 40.8 0.99 8.7 27.8 2.2 2 0 0 2 2 2 0 BUD22 SWI-SNF_Ssr4 PF08549.10 EGO59421.1 - 1.4 7.4 11.8 2 7.0 11.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) FAM60A PF15396.6 EGO59421.1 - 2.1 8.3 11.5 0.14 12.1 6.5 1.5 2 0 0 2 2 2 0 Protein Family FAM60A CSRNP_N PF16019.5 EGO59421.1 - 6.2 6.7 10.3 7.2 6.5 7.7 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Methyltransf_23 PF13489.6 EGO59422.1 - 1.5e-16 60.6 0.0 2.3e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO59422.1 - 5.9e-10 39.7 0.0 2.2e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO59422.1 - 3.4e-08 33.4 0.0 0.0044 16.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGO59422.1 - 4.2e-08 33.7 0.0 9.1e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EGO59422.1 - 0.00012 22.3 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EGO59422.1 - 0.00019 20.9 0.0 0.0015 17.9 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGO59422.1 - 0.00062 20.5 0.0 0.0041 17.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGO59422.1 - 0.0026 17.1 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 EGO59422.1 - 0.0082 15.6 0.1 0.025 14.1 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EGO59422.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Cupin_8 PF13621.6 EGO59423.1 - 2.2e-30 106.2 0.0 4.4e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGO59423.1 - 3.7e-10 39.8 0.0 7.9e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 EGO59423.1 - 0.00028 21.3 0.0 0.0071 16.8 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EGO59423.1 - 0.023 14.4 0.1 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Cupin domain Glycos_transf_4 PF00953.21 EGO59424.1 - 8.2e-33 113.6 10.6 8.2e-33 113.6 10.6 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 4 WD40 PF00400.32 EGO59425.1 - 1.9e-07 31.6 5.9 0.0009 20.0 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EGO59425.1 - 0.059 12.3 0.1 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MFS_1 PF07690.16 EGO59426.1 - 4.9e-25 88.2 48.8 1.3e-23 83.5 31.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Holin_SPP1 PF04688.13 EGO59426.1 - 0.18 12.0 0.1 3.3 8.0 0.1 2.6 2 0 0 2 2 2 0 SPP1 phage holin FKBP_C PF00254.28 EGO59429.1 - 1.2e-20 73.6 0.0 1.4e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ThiF PF00899.21 EGO59430.1 - 1.9e-112 374.5 0.0 5.8e-77 258.3 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EGO59430.1 - 4.2e-91 305.3 4.1 9e-91 304.3 3.2 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EGO59430.1 - 2.8e-32 110.7 0.1 6.3e-32 109.6 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EGO59430.1 - 2.8e-31 108.0 0.1 1.3e-30 106.0 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin fold domain E1_4HB PF16191.5 EGO59430.1 - 7.1e-27 93.4 0.3 2e-26 92.0 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle End_beta_barrel PF12195.8 EGO59430.1 - 0.37 10.8 2.5 23 5.1 0.0 2.6 1 1 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase DUF445 PF04286.12 EGO59431.1 - 0.014 15.2 1.1 0.018 14.8 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF2791 PF10923.8 EGO59431.1 - 0.058 12.2 2.0 0.089 11.6 2.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Spore_III_AB PF09548.10 EGO59431.1 - 0.14 12.2 0.8 0.46 10.6 0.8 1.9 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) EnY2 PF10163.9 EGO59431.1 - 0.58 10.6 6.9 0.97 9.9 5.6 2.1 1 1 1 2 2 2 0 Transcription factor e(y)2 GST_N_2 PF13409.6 EGO59433.1 - 1.8e-23 82.6 0.0 7.5e-23 80.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO59433.1 - 2.5e-16 59.4 0.0 6.7e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO59433.1 - 3.3e-06 27.2 0.0 6.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGO59433.1 - 1e-05 25.8 0.0 0.039 14.4 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO59433.1 - 0.0017 18.5 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain QIL1 PF15884.5 EGO59433.1 - 0.035 14.7 0.1 0.4 11.3 0.1 2.4 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 GST_C_5 PF16865.5 EGO59433.1 - 0.038 14.6 0.0 0.086 13.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tropomyosin_1 PF12718.7 EGO59433.1 - 0.061 13.5 0.4 0.099 12.8 0.4 1.2 1 0 0 1 1 1 0 Tropomyosin like DUF5613 PF18467.1 EGO59436.1 - 0.059 13.8 0.3 0.16 12.4 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5613) DUF809 PF05663.11 EGO59436.1 - 0.17 12.0 0.6 0.29 11.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) PAP_assoc PF03828.19 EGO59438.1 - 3.2e-18 65.7 0.1 5.3e-13 49.0 0.0 2.6 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EGO59438.1 - 0.0028 17.9 0.0 0.0069 16.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain TFIIF_alpha PF05793.12 EGO59439.1 - 1.3e-05 24.0 54.7 1.4e-05 23.9 6.4 2.7 1 1 2 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bud13 PF09736.9 EGO59441.1 - 1.8e-49 167.9 10.6 1.8e-49 167.9 10.6 3.0 2 2 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex Cytomega_UL20A PF05984.12 EGO59441.1 - 1.4 9.3 6.3 0.27 11.5 2.2 1.9 1 1 1 2 2 2 0 Cytomegalovirus UL20A protein Zn_clus PF00172.18 EGO59443.1 - 2.5e-06 27.5 10.5 4e-06 26.8 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 EGO59443.1 - 0.0049 16.5 9.1 0.0049 16.5 9.1 2.2 2 0 0 2 2 2 1 Spt20 family Nop53 PF07767.11 EGO59443.1 - 0.017 14.5 4.7 0.032 13.6 4.7 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CREPT PF16566.5 EGO59443.1 - 0.41 10.8 10.7 0.8 9.9 10.7 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour ANAPC_CDC26 PF10471.9 EGO59443.1 - 1.4 9.8 22.3 0.043 14.7 8.7 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF4407 PF14362.6 EGO59443.1 - 5 6.4 8.6 1.9 7.8 5.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SKI PF01202.22 EGO59444.1 - 3.4e-26 92.3 0.0 6.2e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase DHquinase_I PF01487.15 EGO59444.1 - 1.5e-17 64.6 0.0 2.8e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 EGO59444.1 - 3.3e-15 56.1 0.0 7.9e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 EGO59444.1 - 5.5e-09 36.2 0.1 1.2e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 EGO59444.1 - 0.00071 19.3 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain F420_oxidored PF03807.17 EGO59444.1 - 0.0063 17.1 0.1 0.019 15.5 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent F-box-like PF12937.7 EGO59445.1 - 0.61 10.0 3.4 1.8 8.5 3.4 1.9 1 1 0 1 1 1 0 F-box-like PI3_PI4_kinase PF00454.27 EGO59447.1 - 2.6e-44 151.9 0.0 3.9e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase XhlA PF10779.9 EGO59448.1 - 0.044 14.0 0.5 0.22 11.7 0.5 2.2 1 0 0 1 1 1 0 Haemolysin XhlA SDP_N PF12278.8 EGO59448.1 - 5 7.3 13.2 2.2 8.4 5.3 2.6 1 1 1 2 2 2 0 Sex determination protein N terminal ResIII PF04851.15 EGO59449.1 - 8.2e-24 84.5 0.0 6.1e-23 81.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGO59449.1 - 3.6e-14 53.0 0.0 7.7e-13 48.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO59449.1 - 6.9e-12 45.5 0.0 1.7e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EGO59449.1 - 0.00033 20.4 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 EGO59449.1 - 0.0028 16.9 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ERCC3_RAD25_C PF16203.5 EGO59449.1 - 0.021 14.0 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Myb_DNA-binding PF00249.31 EGO59450.1 - 0.00058 20.0 0.0 0.0019 18.3 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain 2_5_RNA_ligase2 PF13563.6 EGO59451.1 - 6.9e-51 172.1 0.2 1.4e-50 171.1 0.2 1.6 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily MJ1316 PF04457.12 EGO59451.1 - 1.1e-19 70.9 0.5 2.7e-19 69.7 0.5 1.7 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain PAP_central PF04928.17 EGO59451.1 - 1.2e-17 63.8 0.0 8.8e-17 60.9 0.0 2.3 2 1 0 2 2 2 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.23 EGO59451.1 - 4.3e-12 46.1 0.0 9.6e-12 44.9 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.23 EGO59451.1 - 0.0007 19.8 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain AKAP7_NLS PF10469.9 EGO59451.1 - 0.0057 16.6 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Exo_endo_phos_2 PF14529.6 EGO59451.1 - 0.016 15.0 0.1 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase RNA_pol_Rpo13 PF12136.8 EGO59451.1 - 10 6.2 10.1 0.075 13.0 0.9 2.3 3 0 0 3 3 3 0 RNA polymerase Rpo13 subunit HTH domain Chitin_synth_2 PF03142.15 EGO59452.1 - 6.1e-248 823.7 2.2 8.1e-248 823.3 2.2 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EGO59452.1 - 2.7e-76 257.2 0.0 1.7e-75 254.6 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 EGO59452.1 - 2.2e-16 59.5 0.1 8.7e-16 57.6 0.1 2.0 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 EGO59452.1 - 3.7e-14 52.6 0.1 5.7e-10 39.2 0.0 3.1 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 EGO59452.1 - 7.3e-13 48.9 6.4 2e-12 47.5 6.4 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGO59452.1 - 1.2e-11 45.0 0.1 2.4e-09 37.4 0.1 2.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGO59452.1 - 9.8e-06 25.5 0.0 0.018 14.8 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_16 PF13191.6 EGO59452.1 - 0.012 16.0 0.0 0.04 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EGO59452.1 - 0.033 13.7 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 EGO59452.1 - 0.064 13.0 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1622 PF07784.11 EGO59452.1 - 0.084 12.8 0.4 12 5.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) AAA_22 PF13401.6 EGO59452.1 - 0.14 12.4 0.1 0.48 10.7 0.1 1.9 1 0 0 1 1 1 0 AAA domain Chitin_synth_2 PF03142.15 EGO59454.1 - 3.8e-229 761.7 0.2 5.5e-229 761.2 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 EGO59454.1 - 3.5e-16 59.1 0.6 1.8e-12 47.2 0.0 3.0 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 EGO59454.1 - 8.8e-16 57.6 1.1 6.3e-15 54.8 1.5 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EGO59454.1 - 7.5e-14 52.1 4.0 7.5e-14 52.1 4.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGO59454.1 - 3.2e-13 50.1 0.1 1.9e-12 47.5 0.0 2.2 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 EGO59454.1 - 5.5e-08 31.5 0.0 1.5e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) Glycos_transf_2 PF00535.26 EGO59454.1 - 0.00045 20.1 0.0 0.1 12.4 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGO59454.1 - 0.00064 19.2 0.0 0.0066 15.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Bacillus_HBL PF05791.11 EGO59454.1 - 0.046 13.5 0.3 0.082 12.7 0.3 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) BCDHK_Adom3 PF10436.9 EGO59455.1 - 6.9e-48 162.5 0.0 9.8e-48 162.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGO59455.1 - 1.9e-09 38.0 0.0 2.5e-07 31.2 0.0 3.3 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.16 EGO59456.1 - 4.7e-06 27.2 1.4 7.5e-06 26.5 0.3 1.8 2 1 0 2 2 2 1 Peptidase inhibitor I9 DAHP_snth_FXD PF18152.1 EGO59456.1 - 0.1 12.4 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain RIBIOP_C PF04950.12 EGO59457.1 - 4.7e-94 315.1 0.0 4.7e-94 315.1 0.0 1.9 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EGO59457.1 - 5.1e-29 100.2 0.1 4.7e-28 97.1 0.0 2.6 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 EGO59457.1 - 1.3e-05 25.6 0.1 7.6e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGO59457.1 - 7.2e-05 23.1 0.0 0.00023 21.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGO59457.1 - 0.00039 20.9 0.9 0.0022 18.5 0.0 2.6 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.12 EGO59457.1 - 0.00099 19.1 0.0 0.0022 17.9 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 EGO59457.1 - 0.0018 18.7 0.1 0.0045 17.4 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 EGO59457.1 - 0.0019 17.8 0.0 0.23 11.0 0.0 2.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGO59457.1 - 0.0029 17.7 0.0 0.012 15.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EGO59457.1 - 0.0034 17.6 0.7 0.0087 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGO59457.1 - 0.0054 17.1 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGO59457.1 - 0.0088 16.1 0.2 0.053 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EGO59457.1 - 0.01 16.1 0.0 0.033 14.4 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 EGO59457.1 - 0.011 14.9 0.4 0.031 13.4 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 EGO59457.1 - 0.018 14.8 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGO59457.1 - 0.019 14.7 0.0 0.095 12.4 0.0 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 EGO59457.1 - 0.032 13.6 1.0 0.05 13.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein cobW PF02492.19 EGO59457.1 - 0.041 13.5 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EGO59457.1 - 0.042 14.2 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EGO59457.1 - 0.046 13.2 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EGO59457.1 - 0.051 13.6 0.0 0.44 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGO59457.1 - 0.067 13.7 7.6 0.27 11.8 0.0 3.9 3 0 0 3 3 2 0 AAA domain Ploopntkinase3 PF18751.1 EGO59457.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 EGO59457.1 - 0.12 12.3 0.0 0.53 10.2 0.0 2.1 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 EGO59457.1 - 0.14 12.0 0.0 0.14 12.0 0.0 2.7 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EGO59457.1 - 0.88 9.5 5.1 0.2 11.6 0.1 2.2 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.6 EGO59457.1 - 1.8 9.0 0.0 1.8 9.0 0.0 4.1 3 1 0 3 3 2 0 AAA domain Radical_SAM PF04055.21 EGO59458.1 - 2e-07 31.5 0.0 3.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EGO59458.1 - 0.0013 19.0 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Serglycin PF04360.12 EGO59459.1 - 0.1 12.6 2.5 0.22 11.5 2.5 1.5 1 0 0 1 1 1 0 Serglycin COG5 PF10392.9 EGO59459.1 - 0.36 11.0 8.6 4.2 7.6 1.5 3.1 2 2 0 2 2 2 0 Golgi transport complex subunit 5 Ribosomal_60s PF00428.19 EGO59459.1 - 2.1 9.0 17.9 0.43 11.2 0.8 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF1681 PF07933.14 EGO59460.1 - 3.8e-56 188.9 0.0 4.8e-56 188.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SBDS_C PF09377.10 EGO59460.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.5 1 1 0 1 1 1 0 SBDS protein C-terminal domain Methyltransf_33 PF10017.9 EGO59462.1 - 3.4e-86 289.2 0.0 4.9e-86 288.7 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 EGO59462.1 - 1.9e-20 73.6 2.2 1.8e-12 47.4 0.3 2.5 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EGO59462.1 - 2.5e-05 24.8 1.1 7.3e-05 23.3 0.7 2.1 2 0 0 2 2 2 1 DinB superfamily DUF3364 PF11844.8 EGO59462.1 - 1.9 8.8 3.4 1.3 9.3 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3364) GFA PF04828.14 EGO59463.1 - 3.5e-06 27.3 17.4 4.6e-05 23.7 0.4 2.8 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Transpos_assoc PF13963.6 EGO59464.1 - 0.11 12.8 5.5 1.1 9.6 0.0 3.3 3 0 0 3 3 3 0 Transposase-associated domain TFIIA PF03153.13 EGO59464.1 - 0.65 9.9 25.4 0.062 13.3 9.5 2.7 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Acetyltransf_1 PF00583.25 EGO59465.1 - 0.002 18.3 0.0 0.0035 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pho86 PF11124.8 EGO59465.1 - 0.017 14.6 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 DUF1345 PF07077.11 EGO59465.1 - 0.084 12.6 0.5 0.14 11.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) PfkB PF00294.24 EGO59466.1 - 5.2e-57 193.4 1.4 6e-57 193.2 1.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Svf1_C PF17187.4 EGO59468.1 - 2.7e-62 209.5 0.1 8.9e-62 207.8 0.0 1.9 3 0 0 3 3 3 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EGO59468.1 - 1.2e-57 194.6 0.0 1.6e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Neur PF00064.18 EGO59468.1 - 0.014 14.2 0.2 0.026 13.3 0.1 1.5 2 0 0 2 2 2 0 Neuraminidase Ribosomal_L11 PF00298.19 EGO59469.1 - 2.8e-28 98.2 0.2 8e-28 96.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EGO59469.1 - 2.5e-27 94.5 0.2 4.4e-27 93.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Pkinase PF00069.25 EGO59470.1 - 4.5e-47 160.6 0.0 1.9e-46 158.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO59470.1 - 3.3e-22 79.0 0.0 5.3e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO59470.1 - 0.0027 17.6 0.3 0.0095 15.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGO59470.1 - 0.03 13.3 0.0 0.052 12.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Cpn10 PF00166.21 EGO59471.1 - 9.1e-30 102.6 0.0 1e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Glyco_hydro_61 PF03443.14 EGO59472.1 - 1.1e-48 166.0 0.6 3.1e-48 164.5 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 SNF2_N PF00176.23 EGO59473.1 - 8.2e-71 238.5 0.3 1.2e-70 238.0 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EGO59473.1 - 7.7e-21 73.8 0.0 1.6e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EGO59473.1 - 1.4e-14 54.3 0.0 6.3e-14 52.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 EGO59473.1 - 2.2e-10 40.2 13.0 7.5e-10 38.5 9.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO59473.1 - 3e-10 39.7 12.0 3e-10 39.7 12.0 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO59473.1 - 1.3e-08 35.0 11.5 1.3e-08 35.0 11.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGO59473.1 - 5e-08 32.7 14.7 8.1e-08 32.0 12.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO59473.1 - 2.1e-07 30.8 10.5 4.9e-07 29.7 10.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGO59473.1 - 5.8e-07 29.4 9.6 5.8e-07 29.4 9.6 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGO59473.1 - 3.1e-06 27.2 11.6 6.8e-06 26.1 11.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EGO59473.1 - 4.6e-05 23.6 9.0 0.00017 21.8 9.0 2.0 1 1 1 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGO59473.1 - 6.4e-05 22.7 10.0 6.4e-05 22.7 10.0 2.2 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-P11 PF03854.14 EGO59473.1 - 0.0023 17.6 10.4 0.009 15.7 2.0 2.7 2 1 1 3 3 3 2 P-11 zinc finger ResIII PF04851.15 EGO59473.1 - 0.0024 17.9 0.0 0.0062 16.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-ANAPC11 PF12861.7 EGO59473.1 - 0.0051 16.8 3.5 0.012 15.6 3.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 EGO59473.1 - 0.0072 16.1 9.3 0.023 14.5 9.0 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 EGO59473.1 - 0.0085 15.9 3.8 0.021 14.7 3.8 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 EGO59473.1 - 0.013 15.6 6.5 0.013 15.6 6.5 2.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 HJURP_mid PF12346.8 EGO59473.1 - 0.022 15.2 0.3 0.2 12.1 0.2 2.6 2 0 0 2 2 2 0 Holliday junction recognition protein-associated repeat zf-RING_4 PF14570.6 EGO59473.1 - 0.066 13.0 8.7 0.21 11.4 8.8 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 EGO59473.1 - 0.097 12.5 2.9 0.65 9.9 0.6 3.0 2 0 0 2 2 2 0 Rad50 zinc hook motif U-box PF04564.15 EGO59473.1 - 0.15 12.2 0.5 0.57 10.4 0.1 2.2 2 0 0 2 2 1 0 U-box domain zinc-ribbons_6 PF07191.12 EGO59473.1 - 1.6 8.8 5.9 3.4 7.7 5.9 1.5 1 0 0 1 1 1 0 zinc-ribbons CDC45 PF02724.14 EGO59476.1 - 1.9 6.7 5.1 2.5 6.3 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3659 PF12396.8 EGO59478.1 - 3.3e-17 62.2 3.3 8.9e-12 44.8 0.9 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) DUF3659 PF12396.8 EGO59480.1 - 2.4e-104 341.2 49.1 1.4e-22 79.3 3.9 5.7 5 0 0 5 5 5 5 Protein of unknown function (DUF3659) GCV_T_C PF08669.11 EGO59480.1 - 0.013 15.4 0.7 14 5.6 0.0 3.7 4 0 0 4 4 4 0 Glycine cleavage T-protein C-terminal barrel domain TPP_enzyme_N PF02776.18 EGO59481.1 - 2.4e-56 190.0 0.1 4.5e-55 185.9 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGO59481.1 - 9.7e-50 168.3 0.1 1.9e-48 164.1 0.1 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGO59481.1 - 1.6e-39 134.8 0.5 1.6e-39 134.8 0.5 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Glyco_transf_4 PF13439.6 EGO59481.1 - 0.068 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Csm1 PF12539.8 EGO59483.1 - 3e-33 114.3 0.2 7.4e-33 113.0 0.2 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 NPV_P10 PF05531.12 EGO59483.1 - 0.031 14.8 0.7 0.031 14.8 0.7 2.7 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2935 PF11155.8 EGO59483.1 - 0.077 13.3 1.1 1.1 9.7 1.1 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) UPF0242 PF06785.11 EGO59483.1 - 0.19 11.8 17.3 4.7 7.3 15.1 2.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5094 PF17015.5 EGO59483.1 - 0.23 11.5 0.0 0.23 11.5 0.0 4.8 4 2 1 5 5 5 0 Domain of unknown function (DUF5094) Allexi_40kDa PF05549.11 EGO59483.1 - 1.4 8.4 8.5 0.44 10.0 4.4 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein Ribonuc_P_40 PF08584.11 EGO59483.1 - 8 5.7 7.6 0.44 9.8 1.0 2.3 3 0 0 3 3 3 0 Ribonuclease P 40kDa (Rpp40) subunit MFS_1 PF07690.16 EGO59484.1 - 4.4e-17 62.0 39.8 1.4e-16 60.3 15.1 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 EGO59484.1 - 3.2e-10 39.9 4.6 3.2e-10 39.9 4.6 1.9 2 0 0 2 2 2 1 Nodulin-like Serinc PF03348.15 EGO59486.1 - 1.6e-163 544.6 6.4 1.8e-163 544.5 6.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) YtpI PF14007.6 EGO59486.1 - 0.55 10.4 5.0 1.1 9.4 3.3 2.5 1 1 0 1 1 1 0 YtpI-like protein Cys_Met_Meta_PP PF01053.20 EGO59487.1 - 2.7e-139 464.0 0.0 3.2e-139 463.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGO59487.1 - 1.6e-06 27.3 0.0 4.8e-06 25.8 0.0 1.7 1 1 1 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGO59487.1 - 2.1e-06 27.3 0.0 8e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EGO59487.1 - 2.8e-06 26.7 0.0 5.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 EGO59487.1 - 9.9e-06 24.3 0.1 2.4e-05 23.0 0.1 1.5 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 EGO59487.1 - 0.11 11.3 0.1 0.28 10.0 0.1 1.5 1 1 0 1 1 1 0 Glycine cleavage system P-protein TQ PF18202.1 EGO59487.1 - 0.15 12.6 0.2 0.56 10.7 0.1 2.0 3 0 0 3 3 3 0 T-Q ester bond containing domain AAA PF00004.29 EGO59488.1 - 5.1e-37 127.2 0.0 8.7e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO59488.1 - 1e-08 34.8 0.1 2.3e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGO59488.1 - 1.9e-05 25.1 0.2 0.00041 20.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EGO59488.1 - 1.9e-05 24.7 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGO59488.1 - 1.9e-05 24.5 0.0 4.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGO59488.1 - 2.6e-05 24.2 0.1 0.00028 20.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGO59488.1 - 0.00028 21.2 0.1 0.0047 17.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EGO59488.1 - 0.00029 21.0 0.0 0.00058 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EGO59488.1 - 0.0019 17.6 0.1 0.0038 16.6 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGO59488.1 - 0.0036 17.1 0.0 0.0081 15.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EGO59488.1 - 0.004 17.3 0.0 0.0079 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EGO59488.1 - 0.0053 16.7 0.0 0.02 14.8 0.0 1.9 1 1 1 2 2 2 1 NACHT domain RNA_helicase PF00910.22 EGO59488.1 - 0.0072 16.7 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TniB PF05621.11 EGO59488.1 - 0.015 14.7 0.0 3.7 6.9 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 EGO59488.1 - 0.016 14.8 0.1 0.067 12.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGO59488.1 - 0.019 14.7 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 EGO59488.1 - 0.024 15.2 0.0 0.051 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EGO59488.1 - 0.037 13.9 0.1 0.11 12.4 0.0 1.7 1 1 1 2 2 2 0 Rad17 P-loop domain TIP49 PF06068.13 EGO59488.1 - 0.04 13.1 0.1 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain NB-ARC PF00931.22 EGO59488.1 - 0.041 13.1 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EGO59488.1 - 0.044 13.7 0.0 0.13 12.1 0.0 1.7 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EGO59488.1 - 0.046 13.4 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGO59488.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 EGO59488.1 - 0.056 12.8 0.0 0.13 11.6 0.0 1.6 1 1 0 1 1 1 0 KaiC DUF815 PF05673.13 EGO59488.1 - 0.064 12.4 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 EGO59488.1 - 0.076 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGO59488.1 - 0.077 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 EGO59488.1 - 0.088 13.3 0.0 0.21 12.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 EGO59488.1 - 0.093 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PGA2 PF07543.12 EGO59488.1 - 0.1 12.6 0.3 6.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 Parvo_NS1 PF01057.17 EGO59488.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 EGO59488.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Bac_DnaA PF00308.18 EGO59488.1 - 0.15 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_17 PF13207.6 EGO59488.1 - 0.17 12.3 1.6 0.33 11.4 0.1 2.2 3 0 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.18 EGO59488.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Clat_adaptor_s PF01217.20 EGO59489.1 - 5.9e-57 191.6 2.0 6.4e-57 191.5 2.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain U3_snoRNA_assoc PF08297.11 EGO59490.1 - 0.025 15.3 0.4 0.025 15.3 0.4 2.7 2 0 0 2 2 2 0 U3 snoRNA associated zf-CCHC_2 PF13696.6 EGO59490.1 - 0.065 13.1 15.7 1.1 9.2 2.4 2.4 2 0 0 2 2 2 0 Zinc knuckle PHD PF00628.29 EGO59490.1 - 0.67 9.9 2.8 1.4 8.9 2.8 1.5 1 0 0 1 1 1 0 PHD-finger Ist1 PF03398.14 EGO59491.1 - 1.3e-62 210.6 2.8 1.6e-62 210.2 2.8 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Ndc1_Nup PF09531.10 EGO59492.1 - 2.5 6.7 11.1 2.6 6.6 11.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIID-18kDa PF02269.16 EGO59493.1 - 1.1e-27 95.9 0.2 6.4e-27 93.4 0.1 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 EGO59493.1 - 0.0085 16.2 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 hTAFII28-like protein conserved region LCM PF04072.14 EGO59494.1 - 1.6e-23 83.7 0.0 2.7e-22 79.6 0.0 2.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase F-box-like PF12937.7 EGO59498.1 - 1.4e-08 34.5 0.1 2.8e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO59498.1 - 8.6e-06 25.5 0.0 2.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain UIM PF02809.20 EGO59498.1 - 0.00026 20.7 15.9 0.0079 16.1 2.2 2.9 3 0 0 3 3 3 2 Ubiquitin interaction motif HypA PF01155.19 EGO59499.1 - 0.54 10.3 25.2 0.076 13.0 1.4 3.5 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYVE_2 PF02318.16 EGO59499.1 - 5 7.4 24.4 3.4 7.9 4.6 2.7 2 1 0 2 2 2 0 FYVE-type zinc finger Helicase_C_3 PF13625.6 EGO59500.1 - 0.1 12.8 0.0 0.13 12.4 0.0 1.3 1 1 0 1 1 1 0 Helicase conserved C-terminal domain CDC27 PF09507.10 EGO59501.1 - 6.8e-120 401.3 25.9 9.1e-120 400.9 25.9 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 PigN PF04987.14 EGO59502.1 - 2.6e-169 563.9 29.4 3.3e-169 563.6 29.4 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EGO59502.1 - 3.5e-09 36.7 2.5 1.9e-07 31.0 2.5 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGO59502.1 - 6.3e-09 35.7 0.1 1e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EGO59502.1 - 0.00036 20.0 0.0 0.0006 19.2 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Fungal_trans PF04082.18 EGO59503.1 - 3.2e-36 124.7 0.0 3.2e-36 124.7 0.0 2.5 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO59503.1 - 0.0015 18.6 1.4 0.0029 17.7 1.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pinin_SDK_memA PF04696.13 EGO59503.1 - 0.26 11.3 45.0 0.03 14.4 24.2 2.5 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Serinc PF03348.15 EGO59503.1 - 9.2 5.1 17.3 0.1 11.5 4.8 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) BRO1 PF03097.18 EGO59504.1 - 1.8e-136 455.0 2.8 1.8e-136 455.0 2.8 2.1 2 1 2 4 4 4 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EGO59504.1 - 2.9e-77 259.9 23.4 2.9e-77 259.9 23.4 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Phage_tail_APC PF16778.5 EGO59504.1 - 0.18 11.7 0.9 1.3 9.0 0.4 2.6 2 0 0 2 2 2 0 Phage tail assembly chaperone protein COG2 PF06148.11 EGO59504.1 - 0.62 10.1 12.1 0.084 13.0 3.6 3.4 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1539 PF07560.11 EGO59504.1 - 0.71 10.0 7.0 0.8 9.8 0.1 3.1 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1539) FlaC_arch PF05377.11 EGO59504.1 - 4.4 7.8 6.1 29 5.1 0.1 3.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Carn_acyltransf PF00755.20 EGO59505.1 - 1.5e-205 684.3 0.0 1.7e-205 684.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SWIRM-assoc_1 PF16495.5 EGO59506.1 - 1.9e-32 111.0 5.0 3.8e-32 110.1 5.0 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 SWIRM PF04433.17 EGO59506.1 - 3e-30 104.4 0.1 6.7e-30 103.3 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 EGO59506.1 - 2e-10 40.7 0.0 4.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO59506.1 - 2.2e-05 24.6 0.3 4.5e-05 23.6 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGO59506.1 - 0.019 15.1 0.1 0.041 14.1 0.1 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EGO59506.1 - 0.025 14.4 1.2 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Myb DNA-binding like DUF3439 PF11921.8 EGO59506.1 - 0.33 10.9 4.1 0.79 9.7 4.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ETF PF01012.21 EGO59507.1 - 8e-45 153.0 4.6 1.2e-44 152.3 4.6 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EGO59507.1 - 6.8e-34 115.8 1.0 1.2e-33 114.9 0.3 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain K_channel_TID PF07941.11 EGO59508.1 - 0.042 14.3 0.7 0.042 14.3 0.7 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF373 PF04123.13 EGO59508.1 - 1.4 8.3 5.7 1.9 7.8 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) PfkB PF00294.24 EGO59509.1 - 1.4e-17 63.9 0.1 3.2e-10 39.8 0.5 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase MCM PF00493.23 EGO59510.1 - 6.2e-98 326.4 0.2 9.2e-98 325.8 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGO59510.1 - 1.6e-31 108.7 0.0 2.9e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGO59510.1 - 2.5e-25 88.7 0.8 5.7e-25 87.6 0.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGO59510.1 - 7.4e-09 36.1 0.0 2.2e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGO59510.1 - 4.4e-07 29.5 0.0 5.5e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGO59510.1 - 0.0019 18.0 0.0 0.0064 16.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGO59510.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Aminotran_3 PF00202.21 EGO59511.1 - 1.1e-86 291.1 0.0 1.3e-86 290.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGO59511.1 - 0.00016 21.0 0.0 0.00041 19.6 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II ZapA PF05164.13 EGO59511.1 - 0.15 12.5 0.2 8.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Cell division protein ZapA Exo70 PF03081.15 EGO59512.1 - 1.2e-91 307.6 0.1 1.6e-90 303.9 0.0 2.3 3 0 0 3 3 3 1 Exo70 exocyst complex subunit ApoLp-III PF07464.11 EGO59512.1 - 0.078 13.1 0.4 2.5 8.2 0.0 3.0 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 EGO59512.1 - 0.27 11.1 6.1 0.76 9.6 0.1 3.6 4 0 0 4 4 4 0 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.12 EGO59512.1 - 0.49 10.9 3.0 26 5.4 0.0 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein PLC-beta_C PF08703.10 EGO59512.1 - 3.7 7.5 6.0 1.1 9.3 0.0 2.9 4 0 0 4 4 4 0 PLC-beta C terminal GAS PF13851.6 EGO59512.1 - 9.5 5.5 10.8 10 5.4 0.2 4.0 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding FAA_hydrolase PF01557.18 EGO59519.1 - 1.4e-55 188.3 0.0 1.9e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MutL_C PF08676.11 EGO59521.1 - 6.2e-23 81.2 0.1 2.4e-22 79.3 0.0 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EGO59521.1 - 3.8e-18 65.3 0.0 9.4e-18 64.0 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EGO59521.1 - 3.3e-11 43.2 0.5 9.9e-11 41.6 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGO59521.1 - 9.8e-06 26.1 0.0 3.2e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3306 PF11748.8 EGO59521.1 - 0.025 15.5 2.8 0.025 15.5 2.8 5.1 5 1 0 5 5 5 0 Protein of unknown function (DUF3306) PGAP1 PF07819.13 EGO59523.1 - 3.8e-92 308.2 0.0 6.4e-92 307.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EGO59523.1 - 8.2e-05 23.3 0.1 0.00019 22.1 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO59523.1 - 0.002 17.4 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO59523.1 - 0.006 16.3 0.0 0.016 14.8 0.0 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 EGO59523.1 - 0.023 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 EGO59523.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 EGO59523.1 - 0.1 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase UL42 PF17638.2 EGO59523.1 - 0.12 12.4 0.4 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 HCMV UL42 TFIIA PF03153.13 EGO59523.1 - 4.7 7.1 8.2 7.6 6.4 8.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PolyA_pol PF01743.20 EGO59524.1 - 3.6e-28 98.5 0.2 8e-28 97.4 0.2 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EGO59524.1 - 3.9e-07 29.7 0.0 1.3e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 EGO59524.1 - 0.00031 20.8 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative Sec7 PF01369.20 EGO59525.1 - 3.6e-66 222.3 0.0 5.6e-66 221.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EGO59525.1 - 1.1e-16 61.1 0.0 1.1e-15 57.8 0.0 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EGO59525.1 - 0.0017 18.0 0.3 0.0017 18.0 0.3 2.2 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Anp1 PF03452.14 EGO59526.1 - 4.9e-115 383.5 0.1 8.7e-115 382.7 0.0 1.4 2 0 0 2 2 2 1 Anp1 Totivirus_coat PF05518.11 EGO59526.1 - 0.61 8.1 3.0 0.85 7.6 3.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein RNase_PH PF01138.21 EGO59528.1 - 8.4e-26 91.0 0.0 1.4e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 GDA1_CD39 PF01150.17 EGO59530.1 - 3.7e-105 352.0 0.0 5.2e-105 351.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF775 PF05603.12 EGO59531.1 - 2.4e-57 193.7 0.0 2.8e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF4743 PF15916.5 EGO59532.1 - 2.1e-12 47.0 0.0 4e-12 46.2 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 EGO59532.1 - 1.1e-08 35.2 0.0 2.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain PAXNEB PF05625.11 EGO59533.1 - 6.7e-105 351.3 0.0 7.9e-105 351.0 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.17 EGO59534.1 - 3.3e-14 52.7 0.0 7e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF4274 PF14096.6 EGO59534.1 - 0.052 13.5 0.0 7.2 6.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4274) zf-C3HC4_3 PF13920.6 EGO59535.1 - 3.4e-07 30.0 16.5 6e-07 29.2 16.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ATP-synt_D PF01813.17 EGO59536.1 - 1.5e-69 233.8 3.2 2e-69 233.4 3.2 1.2 1 0 0 1 1 1 1 ATP synthase subunit D YdfA_immunity PF12127.8 EGO59536.1 - 0.037 13.1 8.2 2.5 7.1 0.0 2.3 2 0 0 2 2 2 0 SigmaW regulon antibacterial CobA_CobO_BtuR PF02572.15 EGO59536.1 - 0.23 11.7 3.5 0.58 10.4 0.1 2.5 1 1 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF5446 PF17522.2 EGO59536.1 - 8.6 6.6 7.1 0.84 9.8 0.7 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5446) Suf PF05843.14 EGO59537.1 - 1e-10 42.1 9.6 0.012 15.7 0.0 6.5 3 2 3 7 7 7 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EGO59537.1 - 1.3e-09 38.1 23.7 1.4 9.9 0.0 11.8 10 3 3 13 13 12 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGO59537.1 - 1.6e-08 34.1 8.7 2.5e-05 23.7 0.5 4.7 2 2 2 4 4 4 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGO59537.1 - 1.2e-06 28.5 12.5 0.23 11.4 0.0 6.7 7 1 0 7 7 7 3 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 EGO59537.1 - 2.4e-05 24.2 3.8 0.68 10.3 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO59537.1 - 0.00032 20.9 3.0 40 4.6 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.9 EGO59537.1 - 0.00097 18.9 1.8 0.017 14.8 0.4 3.4 3 2 0 3 3 3 1 26S proteasome subunit RPN7 NRDE-2 PF08424.10 EGO59537.1 - 0.003 16.7 18.3 0.012 14.7 0.5 6.5 3 2 1 5 5 5 1 NRDE-2, necessary for RNA interference TPR_2 PF07719.17 EGO59537.1 - 0.0033 17.4 14.9 4.9 7.5 0.0 6.9 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 EGO59537.1 - 0.044 14.4 0.1 12 6.8 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat HAT PF02184.16 EGO59537.1 - 1.1 9.2 18.0 5.3 7.1 1.6 7.5 7 1 0 7 7 7 0 HAT (Half-A-TPR) repeat TPR_10 PF13374.6 EGO59537.1 - 2.3 8.2 10.8 42 4.2 0.0 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat Egh16-like PF11327.8 EGO59539.1 - 2.8e-53 181.0 6.9 2.8e-53 181.0 6.9 1.3 2 0 0 2 2 2 1 Egh16-like virulence factor SAM_Exu PF18609.1 EGO59540.1 - 0.065 13.3 0.2 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 Exuperantia SAM-like domain DivIVA PF05103.13 EGO59540.1 - 0.15 12.2 0.8 0.31 11.1 0.6 1.6 2 0 0 2 2 2 0 DivIVA protein zf-C3HC4_3 PF13920.6 EGO59541.1 - 0.0014 18.4 3.2 0.0023 17.8 2.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO59541.1 - 0.0018 18.2 6.5 0.025 14.5 6.5 2.3 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGO59541.1 - 0.0036 17.1 2.4 0.0076 16.1 2.4 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 TackOD1 PF18551.1 EGO59541.1 - 0.077 12.7 3.3 0.092 12.4 3.3 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf-RING_UBOX PF13445.6 EGO59541.1 - 0.078 13.0 2.3 1.4 9.0 0.7 2.5 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EGO59541.1 - 0.085 12.7 2.8 0.16 11.9 2.8 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO59541.1 - 0.085 13.2 3.5 0.21 12.0 3.4 1.9 1 1 0 1 1 1 0 Ring finger domain zinc-ribbons_6 PF07191.12 EGO59541.1 - 0.089 12.8 4.9 1.7 8.7 3.7 2.3 1 1 1 2 2 2 0 zinc-ribbons Rad50_zn_hook PF04423.14 EGO59541.1 - 0.12 12.2 0.2 0.18 11.6 0.2 1.3 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C3HC4_5 PF17121.5 EGO59541.1 - 0.2 11.6 2.7 0.34 10.8 2.7 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 EGO59541.1 - 0.2 11.7 6.6 2.4 8.3 2.8 2.3 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.19 EGO59541.1 - 0.21 11.6 2.4 0.39 10.8 2.4 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_L32p PF01783.23 EGO59541.1 - 0.52 10.6 2.8 0.55 10.5 0.2 2.2 1 1 1 2 2 2 0 Ribosomal L32p protein family ThiF PF00899.21 EGO59542.1 - 6.7e-17 61.7 0.0 2.2e-16 60.0 0.0 1.9 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 EGO59542.1 - 0.014 15.5 0.3 0.37 11.0 0.1 3.2 3 1 0 3 3 3 0 Ubiquitin-activating enzyme E1 four-helix bundle Disulph_isomer PF06491.11 EGO59543.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.4 1 1 0 1 1 1 0 Disulphide isomerase Fungal_trans PF04082.18 EGO59545.1 - 1.4e-24 86.6 0.0 2.3e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO59545.1 - 4e-07 30.0 12.6 7e-07 29.3 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Haem_oxygenas_2 PF14518.6 EGO59545.1 - 0.0097 15.7 0.2 0.025 14.3 0.2 1.7 1 0 0 1 1 1 1 Iron-containing redox enzyme adh_short PF00106.25 EGO59546.1 - 2.2e-52 177.3 0.1 3e-52 176.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO59546.1 - 3.7e-35 121.6 0.1 4.7e-35 121.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO59546.1 - 6.7e-12 45.7 0.0 1e-11 45.1 0.0 1.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGO59546.1 - 0.044 12.9 0.1 0.099 11.8 0.1 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein PEMT PF04191.13 EGO59547.1 - 2.7e-58 194.9 9.5 4.4e-37 126.7 1.9 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 EGO59547.1 - 0.038 13.8 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 EGO59547.1 - 0.14 12.7 2.6 0.44 11.1 0.0 2.6 2 1 0 2 2 2 0 SKICH domain eIF3g PF12353.8 EGO59548.1 - 3.7e-43 146.9 1.3 6.6e-43 146.1 1.3 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EGO59548.1 - 4e-16 58.6 0.0 8.2e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 EGO59548.1 - 0.025 14.9 0.2 0.049 14.0 0.2 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 RRM_occluded PF16842.5 EGO59548.1 - 0.076 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif ADP_PFK_GK PF04587.15 EGO59548.1 - 0.22 10.1 0.0 0.34 9.4 0.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region PH PF00169.29 EGO59549.1 - 0.12 12.8 0.0 0.31 11.6 0.0 1.7 1 1 0 1 1 1 0 PH domain DAO PF01266.24 EGO59550.1 - 7.3e-64 216.6 1.2 9.3e-64 216.2 1.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO59550.1 - 3.2e-05 24.1 0.3 7.5e-05 22.9 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO59550.1 - 0.0019 17.5 0.1 0.048 12.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EGO59550.1 - 0.0077 14.8 0.1 1.5 7.3 0.0 2.3 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 EGO59550.1 - 0.082 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 EGO59550.1 - 0.086 12.0 0.1 4.6 6.3 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EGO59550.1 - 0.15 12.6 0.0 0.62 10.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2046 PF09755.9 EGO59551.1 - 0.0013 18.0 1.7 0.0027 17.0 0.2 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) DMSP_lyase PF16867.5 EGO59551.1 - 0.017 14.8 0.1 0.045 13.4 0.1 1.6 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase CENP-F_N PF10481.9 EGO59551.1 - 0.018 14.7 0.9 1.4 8.5 0.2 2.4 2 0 0 2 2 2 0 Cenp-F N-terminal domain TMCO5 PF14992.6 EGO59551.1 - 0.068 12.7 2.1 1.1 8.7 0.1 2.0 2 0 0 2 2 2 0 TMCO5 family SlyX PF04102.12 EGO59551.1 - 0.17 12.5 6.4 5.7 7.6 1.3 2.5 2 0 0 2 2 2 0 SlyX JAKMIP_CC3 PF16034.5 EGO59551.1 - 0.87 9.5 10.9 0.071 13.0 4.3 2.3 2 1 0 2 2 2 0 JAKMIP CC3 domain GET2 PF08690.10 EGO59551.1 - 5 6.7 7.5 14 5.2 7.5 1.8 1 1 0 1 1 1 0 GET complex subunit GET2 DUF2415 PF10313.9 EGO59552.1 - 3.2e-15 55.8 0.0 8.7e-15 54.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 EGO59552.1 - 0.0016 19.2 0.3 20 6.3 0.0 4.0 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO59552.1 - 0.0024 18.1 0.0 0.47 10.8 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain HSP70 PF00012.20 EGO59553.1 - 1.7e-268 891.8 15.3 1.9e-268 891.6 15.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGO59553.1 - 8.9e-15 54.3 5.0 4.4e-13 48.8 1.2 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EGO59553.1 - 2.1e-05 24.3 0.1 0.00011 22.0 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 EGO59553.1 - 0.0094 15.2 3.1 0.096 11.9 0.1 3.0 3 1 1 4 4 4 1 StbA protein Med9 PF07544.13 EGO59553.1 - 3.8 7.7 5.9 8.3 6.6 0.3 2.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SRP68 PF16969.5 EGO59554.1 - 1.8e-209 697.4 10.7 2.4e-209 697.0 10.7 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 PPR_2 PF13041.6 EGO59555.1 - 3.8e-21 75.0 1.8 2.1e-06 27.8 0.1 7.5 5 1 3 8 8 8 4 PPR repeat family PPR PF01535.20 EGO59555.1 - 4.3e-16 58.0 5.6 0.0044 17.2 0.0 8.4 8 0 0 8 8 8 3 PPR repeat PPR_3 PF13812.6 EGO59555.1 - 1.1e-10 41.4 2.5 0.015 15.3 0.0 5.8 3 2 3 6 6 6 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGO59555.1 - 5.9e-07 29.1 0.1 0.0046 16.6 0.0 5.1 6 0 0 6 6 6 1 PPR repeat TPR_14 PF13428.6 EGO59555.1 - 0.00013 22.5 13.4 0.12 13.3 0.0 7.8 10 0 0 10 10 10 1 Tetratricopeptide repeat PPR_long PF17177.4 EGO59555.1 - 0.00026 20.5 0.1 0.79 9.0 0.0 2.6 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_16 PF13432.6 EGO59555.1 - 0.0069 17.0 0.6 9.5 7.0 0.2 3.7 2 1 0 2 2 2 1 Tetratricopeptide repeat Suf PF05843.14 EGO59555.1 - 0.012 15.6 0.3 11 5.9 0.0 3.5 2 1 1 3 3 3 0 Suppressor of forked protein (Suf) FSH1 PF03959.13 EGO59556.1 - 3.9e-29 101.8 0.0 1.8e-22 80.1 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EGO59556.1 - 3.8e-05 23.6 0.0 0.00013 21.9 0.0 1.9 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EGO59556.1 - 0.00054 20.6 0.1 0.0007 20.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.10 EGO59556.1 - 0.014 14.5 0.0 0.28 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Syja_N PF02383.18 EGO59559.1 - 1.2e-77 261.4 0.0 2.3e-77 260.5 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain Tti2 PF10521.9 EGO59560.1 - 2.8e-91 305.9 0.1 5.3e-91 305.1 0.1 1.5 1 0 0 1 1 1 1 Tti2 family DUF3114 PF11311.8 EGO59560.1 - 0.21 11.1 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) GalKase_gal_bdg PF10509.9 EGO59561.1 - 3.1e-22 77.8 0.0 5.5e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EGO59561.1 - 3.5e-15 56.0 2.1 3.5e-15 56.0 2.1 2.5 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGO59561.1 - 5.1e-14 52.4 0.0 1.6e-13 50.8 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Reprolysin_4 PF13583.6 EGO59561.1 - 0.087 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Sigma70_r4_2 PF08281.12 EGO59561.1 - 0.099 12.3 0.1 0.23 11.1 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 SR-25 PF10500.9 EGO59561.1 - 0.58 9.7 9.1 1.2 8.7 9.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FANCL_C PF11793.8 EGO59562.1 - 0.00018 21.6 8.2 0.00032 20.8 8.2 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 EGO59562.1 - 0.00026 21.1 11.4 0.00041 20.4 11.4 1.3 1 0 0 1 1 1 1 RING-variant domain CopD PF05425.13 EGO59562.1 - 0.0072 16.7 3.3 1.3 9.4 0.0 2.3 2 0 0 2 2 2 2 Copper resistance protein D zf-RING_2 PF13639.6 EGO59562.1 - 0.019 15.3 12.6 0.028 14.7 12.6 1.3 1 0 0 1 1 1 0 Ring finger domain zf-UDP PF14569.6 EGO59562.1 - 0.27 11.4 6.2 0.55 10.4 4.9 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 EGO59562.1 - 1.9 8.3 11.3 5.2 6.9 11.2 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain SGTA_dimer PF16546.5 EGO59563.1 - 9.2e-26 89.4 0.3 1.8e-25 88.5 0.3 1.5 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 EGO59563.1 - 1.2e-18 66.1 4.4 4.5e-08 32.6 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGO59563.1 - 8.8e-16 56.7 6.6 2.1e-05 24.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO59563.1 - 4.2e-10 39.0 4.4 0.011 15.9 0.1 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGO59563.1 - 2.8e-09 36.5 5.7 0.00038 20.1 0.4 3.4 2 1 1 3 3 3 3 TPR repeat TPR_16 PF13432.6 EGO59563.1 - 1.2e-07 32.3 14.6 0.00023 21.7 6.6 3.3 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGO59563.1 - 1.5e-07 31.8 2.7 0.002 18.6 0.2 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGO59563.1 - 7.3e-07 29.5 8.0 0.11 13.4 3.2 4.3 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGO59563.1 - 1.1e-06 28.5 2.9 0.023 15.0 0.2 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGO59563.1 - 1.2e-06 28.1 0.3 0.03 14.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGO59563.1 - 1.2e-05 25.5 4.9 9.5e-05 22.6 1.2 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGO59563.1 - 0.00016 21.7 1.1 0.0024 18.0 1.4 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat STI1 PF17830.1 EGO59563.1 - 0.0003 20.7 10.0 0.00092 19.1 6.5 2.4 2 0 0 2 2 2 1 STI1 domain DUF3446 PF11928.8 EGO59563.1 - 0.0032 17.7 4.3 0.0078 16.5 4.3 1.6 1 0 0 1 1 1 1 Early growth response N-terminal domain BTAD PF03704.17 EGO59563.1 - 0.0072 16.8 2.1 0.17 12.3 1.4 2.3 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 EGO59563.1 - 0.016 15.8 5.7 0.38 11.5 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat XPC-binding PF09280.11 EGO59563.1 - 0.019 14.7 3.6 0.059 13.1 3.6 1.8 1 0 0 1 1 1 0 XPC-binding domain GHBP PF12772.7 EGO59563.1 - 0.031 13.8 1.3 0.044 13.3 1.3 1.1 1 0 0 1 1 1 0 Growth hormone receptor binding SR-25 PF10500.9 EGO59563.1 - 0.072 12.7 7.3 0.11 12.0 7.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_10 PF13374.6 EGO59563.1 - 0.093 12.6 7.6 0.17 11.8 2.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EGO59563.1 - 0.099 12.7 5.0 4.5 7.4 0.1 3.3 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain RAP1 PF07218.11 EGO59563.1 - 1.9 6.7 4.3 2.4 6.3 4.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) GATase_5 PF13507.6 EGO59564.1 - 1e-101 339.5 0.0 1.8e-101 338.6 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EGO59564.1 - 8.9e-41 139.6 1.0 2.4e-26 92.7 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EGO59564.1 - 4e-25 88.1 0.0 6.9e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EGO59564.1 - 5.1e-23 81.4 0.1 1.2e-22 80.2 0.1 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain MRP-L28 PF09812.9 EGO59565.1 - 1.4e-06 28.6 0.1 1.4e-06 28.6 0.1 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L28 Ras PF00071.22 EGO59566.1 - 2.5e-50 170.2 0.0 2.9e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO59566.1 - 1.6e-22 80.0 0.0 2.3e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO59566.1 - 2.6e-06 27.0 0.0 3.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGO59566.1 - 0.0077 15.7 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_21 PF13304.6 EGO59566.1 - 0.053 13.3 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Gtr1_RagA PF04670.12 EGO59566.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EGO59566.1 - 0.16 11.7 0.2 5.6 6.7 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EGO59566.1 - 0.17 12.0 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase NST1 PF13945.6 EGO59568.1 - 4.6e-53 180.2 15.7 4.6e-53 180.2 15.7 4.6 2 2 2 4 4 4 1 Salt tolerance down-regulator TMIE PF16038.5 EGO59569.1 - 0.0085 15.9 0.4 0.015 15.1 0.4 1.3 1 0 0 1 1 1 1 TMIE protein DUF3552 PF12072.8 EGO59569.1 - 0.014 14.8 1.7 0.023 14.1 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Nop14 PF04147.12 EGO59571.1 - 0.0015 16.9 10.8 0.0015 16.9 10.8 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2828 PF11443.8 EGO59571.1 - 0.33 9.0 8.1 0.33 9.0 8.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) MAP7 PF05672.11 EGO59571.1 - 0.37 10.5 35.8 0.48 10.1 35.8 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family RR_TM4-6 PF06459.12 EGO59571.1 - 0.5 10.1 11.5 0.46 10.3 11.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 EGO59571.1 - 1.9 7.7 8.6 2.1 7.6 8.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DNA_pol3_a_NII PF11490.8 EGO59571.1 - 7.3 6.5 19.5 0.089 12.7 9.7 2.0 1 1 1 2 2 2 0 DNA polymerase III polC-type N-terminus II Pre-PUA PF17832.1 EGO59573.1 - 3.1e-20 72.7 1.1 4.6e-20 72.1 1.1 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EGO59573.1 - 1.1e-12 47.8 0.1 1e-05 25.4 0.0 2.2 2 0 0 2 2 2 2 PUA domain Inhibitor_I78 PF11720.8 EGO59574.1 - 3.9e-10 39.6 0.0 4.6e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 EGO59574.1 - 0.00045 20.8 0.0 0.0007 20.2 0.0 1.3 1 0 0 1 1 1 1 Potato inhibitor I family DUF1772 PF08592.11 EGO59576.1 - 9.4e-10 38.9 0.0 2e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2189 PF09955.9 EGO59576.1 - 0.2 11.9 3.3 12 6.1 1.3 2.9 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2189) PPR_2 PF13041.6 EGO59578.1 - 3.7e-44 148.7 16.1 1.1e-10 41.5 0.1 13.1 10 5 6 16 16 16 7 PPR repeat family PPR_3 PF13812.6 EGO59578.1 - 7.3e-37 125.3 0.4 0.001 19.1 0.0 10.1 9 2 1 10 10 10 9 Pentatricopeptide repeat domain PPR PF01535.20 EGO59578.1 - 7e-25 85.5 30.3 0.00011 22.1 0.3 13.7 16 0 0 16 16 16 6 PPR repeat PPR_1 PF12854.7 EGO59578.1 - 4.1e-21 74.4 3.9 8.8e-08 31.7 0.0 10.4 11 0 0 11 11 11 3 PPR repeat PPR_long PF17177.4 EGO59578.1 - 7.3e-16 58.2 17.8 1.9e-07 30.7 0.0 6.9 4 2 4 8 8 8 6 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 EGO59578.1 - 0.00011 22.5 0.0 0.0012 19.2 0.0 2.7 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 EGO59578.1 - 0.019 14.8 0.3 0.26 11.2 0.1 3.1 3 1 1 4 4 4 0 Mitochondrial ATPase expression CREPT PF16566.5 EGO59578.1 - 0.2 11.8 1.3 0.45 10.7 0.1 2.2 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour APG6_N PF17675.1 EGO59578.1 - 1.1 9.8 4.1 2.6 8.6 4.1 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region GHMP_kinases_N PF00288.26 EGO59580.1 - 1.5e-16 60.4 2.8 1.5e-16 60.4 2.8 1.9 1 1 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGO59580.1 - 1.1e-07 32.1 0.4 2.8e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal Gluconate_2-dh3 PF13618.6 EGO59580.1 - 0.048 13.9 0.0 0.16 12.2 0.0 2.1 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 PSK_trans_fac PF07704.11 EGO59580.1 - 0.42 11.4 1.9 0.58 10.9 0.2 2.3 2 1 0 2 2 2 0 Rv0623-like transcription factor Zn_peptidase PF04228.13 EGO59581.1 - 0.0021 17.6 2.7 0.0021 17.6 2.7 2.0 2 0 0 2 2 2 1 Putative neutral zinc metallopeptidase RTX PF02382.15 EGO59581.1 - 0.072 12.8 2.6 0.11 12.1 2.6 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein CSRNP_N PF16019.5 EGO59581.1 - 1.2 9.0 6.8 3.1 7.7 1.3 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Roughex PF06020.11 EGO59581.1 - 3.7 6.6 9.4 6.9 5.7 9.4 1.4 1 0 0 1 1 1 0 Drosophila roughex protein FliD_N PF02465.18 EGO59581.1 - 3.9 8.2 16.3 0.16 12.7 9.4 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Presenilin PF01080.17 EGO59581.1 - 4.5 5.9 8.1 0.85 8.3 1.9 2.0 2 0 0 2 2 2 0 Presenilin EPL1 PF10513.9 EGO59581.1 - 4.6 7.6 11.1 3.3 8.1 2.2 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Aldedh PF00171.22 EGO59582.1 - 9e-133 443.2 0.1 1e-132 443.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGO59582.1 - 1.2e-05 24.6 0.0 2.1e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 EGO59582.1 - 0.015 14.8 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF1489 PF07370.11 EGO59582.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) RRM_1 PF00076.22 EGO59583.1 - 2e-07 30.7 0.0 1.8e-05 24.4 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dmrt1 PF12374.8 EGO59583.1 - 0.012 16.0 0.8 0.028 14.9 0.8 1.6 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 DUF3439 PF11921.8 EGO59583.1 - 0.1 12.6 2.5 0.19 11.7 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 EGO59583.1 - 0.3 9.2 4.9 0.4 8.8 4.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AJAP1_PANP_C PF15298.6 EGO59583.1 - 0.78 9.9 9.5 0.29 11.3 6.0 2.0 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Pyocin_S PF06958.12 EGO59583.1 - 2.8 8.5 5.9 5.5 7.5 5.9 1.4 1 0 0 1 1 1 0 S-type Pyocin Mucin PF01456.17 EGO59583.1 - 3.8 7.5 12.8 0.16 12.0 7.1 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein HAD_2 PF13419.6 EGO59585.1 - 4.1e-16 59.6 0.0 1.6e-07 31.6 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGO59585.1 - 1.6e-07 31.9 0.0 6.6e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO59585.1 - 0.0019 18.2 0.0 0.0054 16.8 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like TPR_11 PF13414.6 EGO59586.1 - 3.3e-07 29.9 1.4 8e-06 25.4 0.7 2.4 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.28 EGO59586.1 - 4.2e-06 26.3 6.8 0.00068 19.4 0.9 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGO59586.1 - 1.2e-05 25.5 1.1 1.2e-05 25.5 1.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGO59586.1 - 2.5e-05 24.0 8.7 0.00079 19.4 0.8 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGO59586.1 - 0.029 15.0 1.0 0.029 15.0 1.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGO59586.1 - 0.041 14.7 0.1 0.041 14.7 0.1 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF4295 PF14128.6 EGO59586.1 - 0.044 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) KdpC PF02669.15 EGO59586.1 - 0.097 12.5 0.7 0.15 11.9 0.1 1.6 2 0 0 2 2 2 0 K+-transporting ATPase, c chain RIF5_SNase_2 PF18189.1 EGO59586.1 - 0.11 12.3 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 TbRIF5 SNase domain 2 ANAPC3 PF12895.7 EGO59586.1 - 0.13 12.5 1.8 0.8 10.0 1.5 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGO59586.1 - 0.33 11.1 3.3 11 6.3 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGO59586.1 - 1 9.4 0.0 1 9.4 0.0 2.8 4 1 1 5 5 5 0 Tetratricopeptide repeat NMD3 PF04981.13 EGO59587.1 - 1.7e-78 263.5 3.8 1.7e-78 263.5 3.8 1.4 2 0 0 2 2 2 1 NMD3 family FYVE_2 PF02318.16 EGO59587.1 - 0.2 11.9 2.1 2.2 8.5 0.6 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger HypA PF01155.19 EGO59587.1 - 0.73 9.9 6.5 8.9 6.4 0.2 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_1 PF00130.22 EGO59587.1 - 1.7 8.6 5.5 6 6.8 1.1 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 EGO59587.1 - 2 8.5 6.0 4.3 7.4 3.7 2.4 2 1 0 2 2 2 0 Double zinc ribbon FYVE PF01363.21 EGO59587.1 - 3.9 7.7 6.2 9.9 6.4 2.4 2.5 2 0 0 2 2 2 0 FYVE zinc finger Tnp_zf-ribbon_2 PF13842.6 EGO59587.1 - 9.1 7.2 9.2 0.84 10.5 0.3 3.2 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon YL1 PF05764.13 EGO59588.1 - 0.01 16.0 2.5 0.016 15.4 0.5 2.0 2 0 0 2 2 2 0 YL1 nuclear protein YajC PF02699.15 EGO59588.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Pantoate_ligase PF02569.15 EGO59589.1 - 5.3e-90 301.3 0.0 6.1e-90 301.0 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase UPF0086 PF01868.16 EGO59590.1 - 2.5e-31 107.4 0.5 3.5e-31 106.9 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Acyltransferase PF01553.21 EGO59591.1 - 1e-17 64.0 0.0 2e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase WD40 PF00400.32 EGO59592.1 - 3.1e-11 43.6 6.2 0.061 14.2 0.1 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Fungal_trans_2 PF11951.8 EGO59593.1 - 2.4e-07 29.9 3.8 2.6e-07 29.8 1.9 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO59593.1 - 0.00049 20.2 14.5 0.00049 20.2 14.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 EGO59593.1 - 0.0068 16.5 4.9 0.0068 16.5 4.9 3.6 4 0 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 Ly49 PF08391.10 EGO59593.1 - 0.027 14.8 0.7 0.075 13.4 0.7 1.7 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Gastrin PF00918.17 EGO59593.1 - 1.5 9.8 7.0 1.5 9.8 1.3 2.7 2 0 0 2 2 2 0 Gastrin/cholecystokinin family Peptidase_S8 PF00082.22 EGO59595.1 - 0.00027 20.3 1.6 0.00055 19.3 1.7 1.4 1 1 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.11 EGO59595.1 - 0.18 12.1 0.0 0.83 9.9 0.0 2.0 1 1 1 2 2 2 0 Pro-kumamolisin, activation domain Sec2p PF06428.11 EGO59596.1 - 0.012 15.6 2.8 0.063 13.2 0.3 2.1 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF3546 PF12066.8 EGO59596.1 - 0.018 15.2 0.5 0.094 12.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) Fungal_trans PF04082.18 EGO59598.1 - 6.1e-10 38.6 2.4 1.1e-09 37.7 2.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO59598.1 - 4.5e-09 36.3 7.0 7.5e-09 35.6 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGO59599.1 - 8.3e-13 48.0 0.0 1.5e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO59599.1 - 2.8e-06 27.4 11.3 4.7e-06 26.6 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Serglycin PF04360.12 EGO59600.1 - 0.18 11.7 2.4 0.31 11.0 0.2 2.4 3 0 0 3 3 3 0 Serglycin Med13_C PF06333.12 EGO59601.1 - 0.044 13.0 7.5 0.047 13.0 6.4 1.5 1 1 1 2 2 2 0 Mediator complex subunit 13 C-terminal domain S1-P1_nuclease PF02265.16 EGO59602.1 - 1.3e-72 244.7 0.0 1.5e-72 244.5 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease SinI PF08671.10 EGO59605.1 - 0.043 13.6 0.0 0.092 12.6 0.0 1.6 1 0 0 1 1 1 0 Anti-repressor SinI Metallophos PF00149.28 EGO59606.1 - 1.4e-17 64.8 0.1 2.5e-17 64.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 EGO59606.1 - 2e-12 47.5 5.1 3.7e-12 46.7 5.1 1.4 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 EGO59606.1 - 8.1e-10 39.4 0.0 1.8e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C fn3 PF00041.21 EGO59606.1 - 0.011 16.0 4.1 0.021 15.2 4.1 1.4 1 0 0 1 1 1 0 Fibronectin type III domain PhoD_N PF16655.5 EGO59606.1 - 0.048 14.2 0.1 0.21 12.2 0.1 2.0 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain MFS_1 PF07690.16 EGO59608.1 - 6.3e-26 91.1 44.0 1.6e-24 86.5 33.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGO59608.1 - 5.6e-06 25.9 23.1 1.3e-05 24.7 23.1 1.5 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB NAD_binding_10 PF13460.6 EGO59610.1 - 7.1e-13 48.8 0.0 1.7e-11 44.3 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Glyco_hydro_7 PF00840.20 EGO59611.1 - 3.4e-200 665.3 23.2 4.3e-200 665.0 23.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 EGO59611.1 - 3.9e-13 49.1 7.2 3.9e-13 49.1 7.2 4.1 4 1 0 4 4 4 1 Fungal cellulose binding domain Gly_transf_sug PF04488.15 EGO59614.1 - 8.3e-12 45.6 0.1 1.9e-11 44.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TAF4 PF05236.14 EGO59614.1 - 0.021 14.6 16.8 0.028 14.2 16.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family MAP7 PF05672.11 EGO59614.1 - 0.2 11.4 36.7 0.28 10.8 36.7 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF2052 PF09747.9 EGO59614.1 - 0.81 9.8 21.0 1.2 9.2 21.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DDHD PF02862.17 EGO59614.1 - 1.6 8.8 9.6 2.5 8.2 9.6 1.2 1 0 0 1 1 1 0 DDHD domain AAA_11 PF13086.6 EGO59614.1 - 4.1 7.1 10.9 5.5 6.7 10.9 1.1 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpc4 PF05132.14 EGO59614.1 - 4.4 7.7 13.2 7.3 7.0 13.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 U79_P34 PF03064.16 EGO59614.1 - 5.5 6.3 20.1 8.5 5.7 20.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4820 PF16091.5 EGO59614.1 - 7.3 5.9 12.5 12 5.2 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Rrp15p PF07890.12 EGO59614.1 - 9.3 6.6 25.4 14 6.0 25.4 1.2 1 0 0 1 1 1 0 Rrp15p HET PF06985.11 EGO59617.1 - 0.0084 16.5 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Transp_cyt_pur PF02133.15 EGO59618.1 - 2.7e-155 517.5 34.4 3.1e-155 517.3 34.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin AAA_5 PF07728.14 EGO59619.1 - 1.9e-09 37.7 0.0 3.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EGO59619.1 - 9.2e-07 29.4 0.0 2.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UBA_4 PF14555.6 EGO59619.1 - 9.5e-05 22.1 0.7 0.00033 20.4 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain AAA_2 PF07724.14 EGO59619.1 - 0.00026 21.2 0.1 0.0033 17.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 EGO59619.1 - 0.00039 20.4 0.1 0.0011 19.0 0.0 1.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.26 EGO59619.1 - 0.0012 18.5 0.0 0.0054 16.5 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EGO59619.1 - 0.0072 15.7 0.1 4.1 6.7 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 EGO59619.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EGO59619.1 - 0.023 15.1 0.0 0.099 13.0 0.0 2.1 2 1 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 EGO59619.1 - 0.03 14.7 0.0 4.8 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EGO59619.1 - 0.049 14.2 0.0 0.48 11.0 0.0 2.5 2 1 1 3 3 3 0 AAA domain Rad17 PF03215.15 EGO59619.1 - 0.053 13.4 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_6 PF12774.7 EGO59619.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_19 PF13245.6 EGO59619.1 - 0.12 12.7 0.0 13 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EGO59619.1 - 0.2 11.4 0.0 2.4 7.9 0.0 2.3 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain FMO-like PF00743.19 EGO59621.1 - 6.5e-19 67.7 0.0 3.8e-18 65.2 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGO59621.1 - 5e-16 58.8 0.2 3.5e-13 49.5 0.3 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO59621.1 - 6.1e-16 58.5 1.9 1.8e-10 40.5 2.4 2.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO59621.1 - 1e-10 41.3 0.1 2.2e-07 30.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EGO59621.1 - 9.8e-06 26.0 4.6 0.084 13.4 1.5 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO59621.1 - 4.5e-05 23.6 2.3 6.2e-05 23.2 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EGO59621.1 - 0.00042 19.7 3.8 0.067 12.5 0.3 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EGO59621.1 - 0.0006 20.2 0.1 0.095 13.1 0.1 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.24 EGO59621.1 - 0.0015 18.2 2.1 0.0015 18.2 2.1 2.6 3 1 1 4 4 4 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EGO59621.1 - 0.005 16.9 0.3 0.14 12.2 0.1 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EGO59621.1 - 0.006 16.6 1.7 1.7 8.6 0.3 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding 3HCDH_N PF02737.18 EGO59621.1 - 0.053 13.4 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EGO59621.1 - 0.11 11.1 4.2 0.19 10.4 0.3 2.5 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 EGO59621.1 - 8.9 5.3 6.9 0.65 9.0 0.6 2.2 3 1 1 4 4 4 0 Glucose inhibited division protein A Sas10_Utp3 PF04000.15 EGO59622.1 - 2.2e-18 66.6 1.6 2.2e-18 66.6 1.6 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family EMP70 PF02990.16 EGO59623.1 - 7.1e-207 688.2 5.9 9.9e-207 687.7 5.9 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 PIRT PF15099.6 EGO59623.1 - 0.5 9.9 4.2 2 8.0 4.2 2.0 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Med4 PF10018.9 EGO59625.1 - 2e-69 233.2 4.3 2.5e-69 232.8 4.3 1.1 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 CENP-N PF05238.13 EGO59625.1 - 0.15 11.4 3.1 0.24 10.7 3.1 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like VIR_N PF15912.5 EGO59625.1 - 0.76 9.3 9.5 1.7 8.1 8.8 1.8 2 0 0 2 2 2 0 Virilizer, N-terminal PBP_sp32 PF07222.12 EGO59625.1 - 6.5 6.1 7.7 13 5.1 7.7 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CDC45 PF02724.14 EGO59625.1 - 6.8 4.9 10.1 10 4.3 10.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DIE2_ALG10 PF04922.12 EGO59626.1 - 3.7e-125 418.3 0.3 4.3e-124 414.8 0.3 2.1 1 1 0 1 1 1 1 DIE2/ALG10 family QCR10 PF09796.9 EGO59626.1 - 1.3e-19 69.9 0.0 1.3e-19 69.9 0.0 3.2 4 0 0 4 4 4 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Glyco_hydro_32N PF00251.20 EGO59628.1 - 0.00026 20.6 0.8 0.0017 18.0 0.2 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Trypsin_2 PF13365.6 EGO59629.1 - 2.4e-20 74.0 0.1 4e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGO59629.1 - 4.2e-05 23.5 0.1 0.00032 20.6 0.1 2.0 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 EGO59629.1 - 0.012 14.3 0.0 0.074 11.7 0.0 1.9 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S32 PF05579.13 EGO59629.1 - 0.016 14.4 0.1 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 KGG PF10685.9 EGO59630.1 - 5.9e-29 99.5 19.2 5.9e-11 42.3 0.9 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif AbiJ_NTD4 PF18863.1 EGO59631.1 - 0.029 14.8 0.0 0.047 14.2 0.0 1.3 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 Glyoxalase PF00903.25 EGO59632.1 - 4.7e-09 36.5 7.1 1e-08 35.4 3.6 2.7 2 2 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Acid_PPase PF12689.7 EGO59633.1 - 4.4e-50 169.8 0.0 3e-24 85.7 0.0 2.1 2 0 0 2 2 2 2 Acid Phosphatase Serglycin PF04360.12 EGO59633.1 - 0.61 10.0 4.8 1.2 9.0 4.8 1.4 1 0 0 1 1 1 0 Serglycin CRAL_TRIO PF00650.20 EGO59634.1 - 6.5e-26 90.9 0.0 1e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGO59634.1 - 1.2e-10 41.4 0.0 2.7e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Coatomer_WDAD PF04053.14 EGO59635.1 - 5.6e-173 576.1 0.0 4.1e-172 573.2 0.0 2.0 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EGO59635.1 - 1.1e-38 130.6 6.2 1e-06 29.3 0.0 8.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO59635.1 - 1.3e-08 35.0 0.1 5.2 7.4 0.0 6.1 3 3 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO59635.1 - 5.5e-07 28.6 2.1 0.017 13.8 0.0 4.9 2 1 2 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EGO59635.1 - 0.0019 18.2 0.1 1.7 8.7 0.0 4.1 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 EGO59635.1 - 0.082 13.1 0.1 0.43 10.8 0.0 2.1 1 1 1 2 2 2 0 C terminal of Calcineurin-like phosphoesterase Mannitol_dh_C PF08125.13 EGO59636.1 - 1.2e-40 139.5 0.2 1.7e-40 139.1 0.2 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EGO59636.1 - 1.5e-19 70.6 1.8 4.1e-19 69.2 0.0 2.4 3 0 0 3 3 3 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 EGO59636.1 - 0.0081 15.8 0.7 0.033 13.8 0.1 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 EGO59636.1 - 0.069 12.8 0.3 0.31 10.7 0.0 2.3 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Telomere_reg-2 PF10193.9 EGO59636.1 - 0.084 13.3 0.7 0.24 11.8 0.1 2.1 3 0 0 3 3 3 0 Telomere length regulation protein DUF2293 PF10056.9 EGO59636.1 - 0.14 12.4 0.8 0.31 11.3 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2293) SapB_1 PF05184.15 EGO59636.1 - 0.79 9.8 2.9 1.1 9.4 0.7 2.6 2 0 0 2 2 2 0 Saposin-like type B, region 1 VWA PF00092.28 EGO59639.1 - 0.00011 22.5 0.0 0.63 10.3 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain Het-C PF07217.11 EGO59639.1 - 0.21 10.1 0.1 0.4 9.2 0.1 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C AAA PF00004.29 EGO59641.1 - 7.5e-12 45.8 0.0 1.5e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGO59641.1 - 3.1e-06 27.5 0.0 7.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGO59641.1 - 7.1e-05 22.6 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EGO59641.1 - 0.00012 22.1 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 EGO59641.1 - 0.00013 22.0 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGO59641.1 - 0.00044 20.4 0.4 0.0036 17.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGO59641.1 - 0.0025 17.6 0.1 0.0062 16.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGO59641.1 - 0.0035 17.4 0.0 0.0067 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO59641.1 - 0.0037 17.7 0.1 0.012 16.0 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 EGO59641.1 - 0.013 15.4 0.1 0.03 14.2 0.1 1.7 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 EGO59641.1 - 0.013 16.0 0.0 0.037 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGO59641.1 - 0.014 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 EGO59641.1 - 0.049 14.0 0.4 0.63 10.4 0.4 2.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGO59641.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase PhoH PF02562.16 EGO59641.1 - 0.092 12.2 0.1 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 EGO59641.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EGO59641.1 - 0.11 12.1 0.1 0.87 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGO59641.1 - 0.14 11.6 0.0 0.73 9.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 EGO59641.1 - 0.28 11.7 0.1 0.28 11.7 0.1 2.1 3 0 0 3 3 1 0 ABC transporter bZIP_2 PF07716.15 EGO59642.1 - 0.0018 18.3 1.5 0.0018 18.3 1.5 2.6 2 0 0 2 2 2 1 Basic region leucine zipper DUF812 PF05667.11 EGO59642.1 - 0.0034 16.4 1.7 0.005 15.8 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Herpes_ICP4_N PF03584.15 EGO59642.1 - 0.0045 16.8 0.4 0.23 11.3 0.1 2.2 2 0 0 2 2 2 1 Herpesvirus ICP4-like protein N-terminal region Uds1 PF15456.6 EGO59642.1 - 0.017 15.3 4.2 0.054 13.7 3.4 2.1 2 0 0 2 2 2 0 Up-regulated During Septation bZIP_1 PF00170.21 EGO59642.1 - 0.019 15.1 0.1 0.019 15.1 0.1 2.9 2 0 0 2 2 2 0 bZIP transcription factor Lipoprotein_20 PF13942.6 EGO59642.1 - 0.03 14.2 2.0 0.059 13.3 2.0 1.4 1 0 0 1 1 1 0 YfhG lipoprotein OmpH PF03938.14 EGO59642.1 - 0.03 14.6 9.6 0.09 13.1 9.6 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GAS PF13851.6 EGO59642.1 - 0.069 12.5 9.4 0.14 11.5 9.4 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FCH PF00611.23 EGO59642.1 - 0.47 10.8 4.8 2.6 8.4 4.0 2.3 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DUF724 PF05266.14 EGO59642.1 - 0.55 10.0 6.9 1.1 9.0 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 EGO59642.1 - 0.81 9.0 4.9 1.6 8.0 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 EGO59642.1 - 2.5 7.3 5.2 4 6.6 5.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein ALMT PF11744.8 EGO59642.1 - 3.1 6.5 4.6 4.4 6.0 4.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter UPF0449 PF15136.6 EGO59642.1 - 6.8 7.2 9.1 4.4 7.8 5.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 LysM PF01476.20 EGO59645.1 - 0.036 14.1 0.0 0.11 12.5 0.0 2.0 2 1 0 2 2 2 0 LysM domain MmgE_PrpD PF03972.14 EGO59645.1 - 0.078 11.5 0.0 0.095 11.2 0.0 1.1 1 0 0 1 1 1 0 MmgE/PrpD family Amidohydro_1 PF01979.20 EGO59646.1 - 2.3e-78 263.9 0.0 2.6e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGO59646.1 - 1.3e-09 38.0 4.0 1.8e-08 34.3 0.2 2.4 2 1 0 2 2 2 2 Amidohydrolase family FAS_I_H PF18314.1 EGO59647.1 - 3.1e-76 255.5 0.0 8.3e-76 254.1 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EGO59647.1 - 8.3e-75 250.6 0.0 1.6e-74 249.6 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 EGO59647.1 - 8.2e-21 74.7 0.0 1.7e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EGO59647.1 - 8.3e-17 61.4 0.0 2e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EGO59647.1 - 8.2e-12 45.2 0.0 1.9e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EGO59647.1 - 0.00017 21.1 0.0 0.00037 20.0 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO59647.1 - 0.0063 16.5 0.0 0.024 14.6 0.0 2.0 1 0 0 1 1 1 1 KR domain DUF1729 PF08354.10 EGO59648.1 - 2.8e-159 529.7 0.0 4.6e-159 529.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EGO59648.1 - 3.4e-89 299.5 0.0 1.9e-87 293.8 0.0 3.4 5 0 0 5 5 5 1 Acyl transferase domain FAS_meander PF17951.1 EGO59648.1 - 6.3e-52 175.3 0.0 1.9e-51 173.7 0.0 1.9 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 EGO59648.1 - 1.4e-39 135.1 0.0 1.9e-38 131.4 0.0 2.6 2 1 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 EGO59648.1 - 1.2e-37 128.2 0.0 2.6e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 EGO59648.1 - 8.5e-37 127.2 0.0 1.9e-36 126.0 0.0 1.6 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 EGO59648.1 - 1.2e-23 83.7 0.1 6.1e-23 81.4 0.1 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase SRP_TPR_like PF17004.5 EGO59649.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.5 1 1 0 1 1 1 0 Putative TPR-like repeat TRAP_alpha PF03896.16 EGO59653.1 - 0.086 12.0 3.2 0.18 11.0 3.2 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit MOSC_N PF03476.16 EGO59653.1 - 0.22 11.4 0.7 0.93 9.4 0.1 2.3 2 1 0 2 2 2 0 MOSC N-terminal beta barrel domain U1snRNP70_N PF12220.8 EGO59653.1 - 0.51 11.0 7.2 0.096 13.3 0.6 2.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Eapp_C PF10238.9 EGO59653.1 - 2.1 8.4 6.0 0.84 9.7 0.7 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein UPF0242 PF06785.11 EGO59654.1 - 0.013 15.6 0.7 0.014 15.5 0.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus VPS9 PF02204.18 EGO59655.1 - 6.8e-28 96.9 0.0 1.3e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EGO59655.1 - 3.8e-16 59.1 0.2 8.3e-16 58.1 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 EGO59655.1 - 2.5e-09 36.6 1.4 4.8e-08 32.6 0.0 3.0 3 0 0 3 3 3 1 CUE domain Asn_synthase PF00733.21 EGO59657.1 - 3e-19 69.9 0.9 1.1e-11 45.1 1.0 3.1 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EGO59657.1 - 6.3e-10 39.0 0.0 1.4e-08 34.7 0.0 3.0 3 1 0 3 3 3 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGO59657.1 - 0.00086 19.5 0.0 0.003 17.7 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 EGO59657.1 - 0.17 11.0 0.0 0.57 9.3 0.0 1.8 2 0 0 2 2 2 0 NAD synthase PAPS_reduct PF01507.19 EGO59657.1 - 0.19 11.8 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family SF3A2 PF16835.5 EGO59658.1 - 1.2e-35 121.7 0.1 1.8e-35 121.2 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EGO59658.1 - 7.1e-06 26.2 0.9 7.1e-06 26.2 0.9 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 EGO59658.1 - 8.5e-05 22.5 0.2 0.00012 22.0 0.2 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 EGO59658.1 - 0.066 12.8 1.5 0.12 12.0 1.5 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CoA_transf_3 PF02515.17 EGO59659.1 - 8.7e-128 426.5 0.0 1e-127 426.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III PHD PF00628.29 EGO59660.1 - 2.5e-09 36.9 7.8 4.2e-09 36.2 7.8 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 EGO59660.1 - 0.0016 18.1 2.4 0.0034 17.0 2.4 1.7 1 1 0 1 1 1 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 EGO59660.1 - 0.01 15.7 6.9 0.01 15.7 6.9 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 EGO59660.1 - 0.035 14.3 2.4 0.075 13.2 2.4 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger PHD_2 PF13831.6 EGO59660.1 - 0.11 12.1 8.9 0.019 14.5 3.7 2.3 2 1 0 2 2 2 0 PHD-finger PRIMA1 PF16101.5 EGO59660.1 - 4.3 7.4 15.8 0.2 11.7 7.9 2.8 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 Pkinase PF00069.25 EGO59661.1 - 1.6e-57 194.9 0.0 2.9e-56 190.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO59661.1 - 1.4e-26 93.3 0.1 1.4e-20 73.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO59661.1 - 7e-05 21.9 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGO59661.1 - 0.0002 21.4 0.3 0.027 14.4 0.3 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGO59661.1 - 0.00094 18.6 0.0 0.0023 17.3 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGO59661.1 - 0.0012 18.2 0.4 0.0023 17.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EGO59661.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EGO59661.1 - 1.4 8.5 4.1 0.95 9.0 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Tim54 PF11711.8 EGO59662.1 - 3.8e-139 463.6 2.0 5.3e-139 463.2 2.0 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Nefa_Nip30_N PF10187.9 EGO59663.1 - 1.4e-24 86.5 0.1 1.5e-24 86.4 0.1 1.0 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Cyclin PF08613.11 EGO59665.1 - 5.4e-10 39.9 0.0 1.1e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin RSN1_7TM PF02714.15 EGO59665.1 - 0.0018 17.7 0.0 0.0027 17.0 0.0 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate Ku_PK_bind PF08785.11 EGO59665.1 - 0.0024 18.0 1.7 1.3 9.2 0.0 2.7 2 1 0 2 2 2 2 Ku C terminal domain like CRC_subunit PF08624.10 EGO59667.1 - 1.6e-53 180.7 0.0 2.4e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CDC45 PF02724.14 EGO59667.1 - 4.9 5.3 4.7 6.6 4.9 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIB PF00382.19 EGO59668.1 - 8.4e-38 128.3 3.9 4.3e-20 71.5 0.2 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EGO59668.1 - 3.2e-15 55.4 1.0 5.7e-15 54.6 1.0 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 EGO59668.1 - 2e-05 24.6 0.1 0.054 13.6 0.0 2.7 1 1 2 3 3 3 2 Cyclin, C-terminal domain zf-ribbon_3 PF13248.6 EGO59668.1 - 0.0068 15.8 0.7 0.26 10.7 0.0 2.4 2 0 0 2 2 2 1 zinc-ribbon domain Sigma70_r4_2 PF08281.12 EGO59668.1 - 0.014 15.1 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Rrf2 PF02082.20 EGO59668.1 - 0.038 14.3 0.0 3.9 7.9 0.0 2.8 2 1 1 3 3 3 0 Transcriptional regulator HTH_36 PF13730.6 EGO59668.1 - 0.066 13.2 0.3 14 5.7 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EGO59668.1 - 0.13 11.7 0.5 3.2 7.2 0.1 2.9 2 1 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.16 EGO59668.1 - 0.16 11.5 0.0 0.54 9.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_5 PF01022.20 EGO59668.1 - 0.17 11.7 0.0 16 5.5 0.0 2.9 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family T4SS PF07996.11 EGO59668.1 - 0.35 11.2 6.4 11 6.4 4.3 2.1 1 1 1 2 2 2 0 Type IV secretion system proteins Cyt-b5 PF00173.28 EGO59670.1 - 2.6e-14 53.1 0.0 3.6e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4291 PF14124.6 EGO59671.1 - 2.1e-67 226.5 0.0 3.7e-67 225.7 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4291) Kelch_5 PF13854.6 EGO59672.1 - 1.5e-16 59.9 13.1 5.7e-07 29.4 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 EGO59672.1 - 3.1e-15 55.8 13.8 7.2e-06 26.1 1.2 5.2 4 1 1 5 5 5 4 Kelch motif Kelch_4 PF13418.6 EGO59672.1 - 9.6e-15 54.3 6.9 0.018 15.0 0.0 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EGO59672.1 - 1.4e-12 47.6 19.9 0.0022 18.2 0.0 7.3 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 EGO59672.1 - 3e-12 45.9 9.9 0.017 14.7 0.4 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EGO59672.1 - 0.013 15.5 10.8 0.5 10.4 0.1 5.1 5 1 0 5 5 5 0 Kelch motif Alpha_GJ PF03229.13 EGO59672.1 - 0.049 14.2 4.9 0.19 12.3 4.9 2.1 1 0 0 1 1 1 0 Alphavirus glycoprotein J Adeno_E3 PF06040.11 EGO59672.1 - 0.17 12.1 1.7 0.78 9.9 0.2 2.3 2 0 0 2 2 2 0 Adenovirus E3 protein DUF3613 PF12266.8 EGO59673.1 - 0.051 13.4 0.1 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) CUE PF02845.16 EGO59674.1 - 1.1e-06 28.2 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain PGI PF00342.19 EGO59675.1 - 1.4e-232 772.6 1.6 1.6e-232 772.4 1.6 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.25 EGO59676.1 - 7e-72 242.0 0.0 9.2e-72 241.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO59676.1 - 3.6e-35 121.5 0.0 5e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGO59676.1 - 6.6e-12 46.0 1.2 1.9e-11 44.4 1.2 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EGO59676.1 - 4.5e-06 25.9 0.1 6.7e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 EGO59676.1 - 0.0051 17.1 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EGO59676.1 - 0.0076 15.6 0.0 0.018 14.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EGO59676.1 - 0.06 13.0 0.1 0.73 9.4 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGO59676.1 - 0.13 11.6 0.2 0.3 10.4 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family rve_3 PF13683.6 EGO59678.1 - 0.0099 15.6 0.4 2.5 7.9 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain ABC_tran PF00005.27 EGO59680.1 - 2.5e-43 147.9 0.0 1.6e-25 90.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGO59680.1 - 1.1e-36 126.9 9.2 7.8e-22 78.2 1.6 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EGO59680.1 - 2.4e-10 40.2 1.6 0.002 17.6 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGO59680.1 - 2e-07 31.3 0.1 0.011 16.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGO59680.1 - 6.8e-07 29.8 0.8 0.071 13.5 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 EGO59680.1 - 1.9e-06 27.9 0.2 0.28 11.0 0.0 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGO59680.1 - 3.1e-06 27.8 0.2 0.015 15.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EGO59680.1 - 4e-06 26.9 0.2 0.082 12.8 0.0 3.0 3 0 0 3 3 2 2 NACHT domain T2SSE PF00437.20 EGO59680.1 - 1.7e-05 24.1 1.9 0.0078 15.3 1.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EGO59680.1 - 2e-05 24.6 0.4 0.024 14.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGO59680.1 - 0.0011 19.0 0.1 0.19 11.8 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EGO59680.1 - 0.0021 17.8 7.3 0.027 14.2 0.7 3.0 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EGO59680.1 - 0.0025 17.4 0.6 0.027 14.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGO59680.1 - 0.0026 17.3 0.2 2.8 7.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 EGO59680.1 - 0.0032 17.8 0.1 1.6 9.1 0.0 2.9 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 EGO59680.1 - 0.0048 16.1 0.1 3.5 6.7 0.1 2.4 2 0 0 2 2 2 2 NB-ARC domain IstB_IS21 PF01695.17 EGO59680.1 - 0.0058 16.4 3.6 5 6.8 0.0 4.3 5 0 0 5 5 4 1 IstB-like ATP binding protein AAA PF00004.29 EGO59680.1 - 0.013 15.9 1.9 2.2 8.7 0.0 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EGO59680.1 - 0.025 14.2 1.7 3.6 7.1 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EGO59680.1 - 0.03 14.3 1.9 2.4 8.0 0.3 2.6 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.9 EGO59680.1 - 0.04 13.2 0.1 1.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF962 PF06127.11 EGO59680.1 - 0.043 13.9 0.4 0.95 9.6 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF962) Dynamin_N PF00350.23 EGO59680.1 - 0.06 13.4 0.1 10 6.2 0.0 2.8 2 0 0 2 2 2 0 Dynamin family TsaE PF02367.17 EGO59680.1 - 0.064 13.3 0.1 8.8 6.3 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 EGO59680.1 - 0.083 13.1 0.0 21 5.4 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 EGO59680.1 - 0.087 12.1 0.4 11 5.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 EGO59680.1 - 0.14 11.9 0.0 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF87 PF01935.17 EGO59680.1 - 0.14 12.2 2.4 0.15 12.1 0.5 2.0 2 0 0 2 2 1 0 Helicase HerA, central domain AAA_18 PF13238.6 EGO59680.1 - 0.18 12.3 0.3 2.6 8.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain Podoplanin PF05808.11 EGO59681.1 - 0.0009 19.4 1.7 0.0015 18.6 1.7 1.3 1 0 0 1 1 1 1 Podoplanin Lar_restr_allev PF14354.6 EGO59682.1 - 0.061 13.7 5.1 0.13 12.7 1.1 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar Polyketide_cyc2 PF10604.9 EGO59683.1 - 0.00017 21.9 0.2 0.0002 21.6 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Shadoo PF14999.6 EGO59684.1 - 1.3 9.2 10.8 2.4 8.3 10.8 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Lactamase_B_2 PF12706.7 EGO59685.1 - 5.6e-32 110.9 0.0 7.6e-31 107.2 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGO59685.1 - 2.6e-11 43.7 0.0 4.7e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGO59685.1 - 2.9e-05 24.2 0.0 0.00026 21.1 0.0 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily DUF218 PF02698.17 EGO59686.1 - 2.3e-15 56.7 0.0 4.3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 DUF218 domain Chorion_2 PF03964.15 EGO59686.1 - 7.6e-05 23.5 3.0 0.002 18.9 0.0 2.7 2 0 0 2 2 2 1 Chorion family 2 Glyco_hydro_92 PF07971.12 EGO59687.1 - 1e-122 410.4 0.1 1.1e-105 354.2 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EGO59687.1 - 1.8e-58 198.3 1.4 2.7e-58 197.7 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain PAS_9 PF13426.7 EGO59689.1 - 3.2e-17 62.7 0.0 3.2e-16 59.5 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EGO59689.1 - 0.058 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold Pyrid_ox_like PF16242.5 EGO59690.1 - 1e-22 80.3 0.0 1.7e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 EGO59690.1 - 2.2e-08 34.2 0.0 4.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FAM209 PF15206.6 EGO59690.1 - 0.13 12.0 0.8 0.26 11.1 0.4 1.7 2 0 0 2 2 2 0 FAM209 family TP_methylase PF00590.20 EGO59691.1 - 2.5e-24 86.4 0.0 3.9e-24 85.8 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.8 EGO59692.1 - 3e-06 27.3 0.2 6.2e-06 26.4 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGO59692.1 - 1.6e-05 25.1 0.2 2.7e-05 24.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 EGO59692.1 - 0.0041 17.2 0.1 0.01 15.9 0.1 1.6 1 0 0 1 1 1 1 DBF zinc finger SNRNP27 PF08648.12 EGO59692.1 - 0.014 15.5 0.2 0.053 13.6 0.2 2.1 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins KfrA_N PF11740.8 EGO59692.1 - 1.2 9.9 18.0 0.052 14.2 9.8 2.1 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF4586 PF15239.6 EGO59692.1 - 1.8 8.6 6.3 0.2 11.8 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4586) BLM_N PF16202.5 EGO59692.1 - 5.5 6.0 9.4 9.3 5.2 9.4 1.3 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein UQ_con PF00179.26 EGO59693.1 - 2.3e-38 131.0 0.0 2.6e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO59693.1 - 0.0046 16.7 0.1 0.015 15.0 0.1 1.8 1 1 1 2 2 2 1 Prokaryotic E2 family B Mito_carr PF00153.27 EGO59694.1 - 6.1e-55 183.1 6.9 8.1e-19 67.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cation_efflux PF01545.21 EGO59695.1 - 1.2e-48 165.5 6.1 1.6e-48 165.1 6.1 1.2 1 0 0 1 1 1 1 Cation efflux family DUF2157 PF09925.9 EGO59695.1 - 0.28 11.0 1.6 13 5.5 0.0 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) SPX PF03105.19 EGO59695.1 - 7.8 6.3 7.1 44 3.8 0.0 2.1 2 0 0 2 2 2 0 SPX domain Glyco_trans_1_4 PF13692.6 EGO59696.1 - 1.7e-05 25.3 0.0 5.3e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 TFIIIC_delta PF12657.7 EGO59697.1 - 5.5e-17 62.3 0.0 2.5e-16 60.2 0.0 2.2 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 EGO59697.1 - 5.7e-08 32.6 2.4 5.6e-07 29.5 2.3 2.5 1 1 1 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex SbcCD_C PF13558.6 EGO59697.1 - 0.096 12.9 0.1 5.6 7.3 0.0 3.0 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit zf-3CxxC_2 PF17180.4 EGO59697.1 - 0.14 12.9 0.8 0.51 11.1 0.8 2.0 1 0 0 1 1 1 0 Zinc-binding domain Peptidase_C13 PF01650.18 EGO59698.1 - 5.3e-41 140.8 0.4 7.6e-41 140.3 0.4 1.2 1 0 0 1 1 1 1 Peptidase C13 family His_Phos_1 PF00300.22 EGO59699.1 - 6.9e-05 22.6 0.5 0.51 10.0 0.0 3.3 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) hNIFK_binding PF12196.8 EGO59699.1 - 0.52 9.8 2.0 16 5.1 0.2 2.7 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK F-box-like PF12937.7 EGO59700.1 - 6e-07 29.3 0.3 1.5e-06 28.0 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EGO59700.1 - 0.0027 17.6 0.1 0.0051 16.7 0.1 1.4 1 0 0 1 1 1 1 F-box F-box PF00646.33 EGO59700.1 - 0.0029 17.5 0.2 0.007 16.2 0.2 1.6 1 0 0 1 1 1 1 F-box domain DUF4238 PF14022.6 EGO59703.1 - 2.4e-69 233.9 0.4 4.5e-69 233.0 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Cytochrom_B561 PF03188.16 EGO59705.1 - 0.0004 20.5 4.6 0.0004 20.5 4.6 2.3 2 1 1 3 3 3 1 Eukaryotic cytochrome b561 Cation_efflux PF01545.21 EGO59705.1 - 0.026 14.3 8.4 0.4 10.4 2.6 2.8 3 0 0 3 3 3 0 Cation efflux family GAPT PF11770.8 EGO59705.1 - 0.2 11.5 0.7 1.5 8.6 0.0 2.3 2 1 0 2 2 2 0 GRB2-binding adapter (GAPT) DUF2231 PF09990.9 EGO59705.1 - 0.48 10.9 13.7 2.7 8.5 1.7 3.0 1 1 2 3 3 3 0 Predicted membrane protein (DUF2231) DUF4381 PF14316.6 EGO59705.1 - 0.83 9.9 9.2 0.068 13.4 1.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) DUF2427 PF10348.9 EGO59705.1 - 1.2 8.9 14.1 0.018 14.8 5.0 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF2427) DUF4293 PF14126.6 EGO59705.1 - 1.6 8.9 7.5 0.87 9.8 4.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Glyco_hydro_72 PF03198.14 EGO59706.1 - 1.4e-118 395.8 3.2 1.7e-118 395.4 3.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EGO59706.1 - 0.00011 21.7 0.4 0.0019 17.7 0.4 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AF-4 PF05110.13 EGO59706.1 - 1.6 6.7 2.3 2 6.4 2.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MARVEL PF01284.23 EGO59707.1 - 0.0094 16.0 2.0 0.013 15.6 2.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain FtsX PF02687.21 EGO59707.1 - 0.24 11.9 4.6 0.32 11.5 4.6 1.2 1 0 0 1 1 1 0 FtsX-like permease family DUF3302 PF11742.8 EGO59707.1 - 1.1 9.5 4.3 2.1 8.6 4.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3302) HAUS6_N PF14661.6 EGO59708.1 - 1e-64 218.2 3.6 1e-64 218.2 3.6 2.0 3 0 0 3 3 3 1 HAUS augmin-like complex subunit 6 N-terminus CitT PF12431.8 EGO59708.1 - 0.56 10.6 1.9 0.92 9.9 0.2 2.4 2 0 0 2 2 2 0 Transcriptional regulator Ribosomal_S21 PF01165.20 EGO59709.1 - 1.5e-13 50.2 4.1 2.3e-13 49.6 4.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 PWI PF01480.17 EGO59710.1 - 2.5e-14 53.4 0.6 7.7e-14 51.8 0.6 1.9 1 0 0 1 1 1 1 PWI domain ECH_1 PF00378.20 EGO59711.1 - 2.6e-55 187.4 0.0 1.9e-42 145.3 0.1 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGO59711.1 - 1.8e-22 80.3 0.8 3.7e-10 39.8 0.2 2.8 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase Glyco_hydro_28 PF00295.17 EGO59712.1 - 2.5e-45 154.9 0.2 3.5e-45 154.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Peptidase_S26 PF10502.9 EGO59713.1 - 0.021 14.6 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Signal peptidase, peptidase S26 Acetyltransf_10 PF13673.7 EGO59714.1 - 1.8e-05 24.7 0.0 2.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO59714.1 - 0.00033 21.0 0.0 0.00052 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO59714.1 - 0.0016 18.6 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGO59714.1 - 0.0095 15.9 0.0 0.021 14.8 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGO59714.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TauD PF02668.16 EGO59716.1 - 5.9e-36 124.6 0.1 7.6e-36 124.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EGO59716.1 - 0.014 14.5 0.3 0.059 12.5 0.1 1.8 2 0 0 2 2 2 0 CsiD FAIM1 PF06905.13 EGO59716.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) Ank_5 PF13857.6 EGO59717.1 - 1.2e-17 63.7 8.8 4.4e-07 30.1 0.7 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGO59717.1 - 2.9e-16 59.6 0.7 4.8e-08 33.4 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO59717.1 - 4.5e-16 57.3 1.2 0.0003 21.0 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EGO59717.1 - 2.2e-14 53.8 1.1 8.6e-14 51.9 1.3 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGO59717.1 - 2e-10 40.6 4.6 4.5e-06 26.9 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat bZIP_1 PF00170.21 EGO59717.1 - 0.0005 20.1 6.1 0.0009 19.3 6.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGO59717.1 - 0.098 12.7 5.8 0.17 12.0 5.8 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Rhodanese PF00581.20 EGO59718.1 - 5.3e-12 46.2 0.2 2.6e-11 44.0 0.2 1.9 1 1 0 1 1 1 1 Rhodanese-like domain RIFIN PF02009.16 EGO59719.1 - 5.8e-05 23.1 0.7 0.00012 22.1 0.7 1.5 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 EGO59719.1 - 0.013 15.4 4.3 0.089 12.7 4.3 2.4 1 1 0 1 1 1 0 TMEM154 protein family DUF4407 PF14362.6 EGO59719.1 - 0.04 13.3 0.0 0.04 13.3 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) DUF4083 PF13314.6 EGO59719.1 - 0.09 12.7 1.7 0.093 12.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Med21 PF11221.8 EGO59719.1 - 6.6 7.0 7.9 8.6 6.6 2.7 2.9 2 1 0 2 2 2 0 Subunit 21 of Mediator complex UPF0121 PF03661.13 EGO59720.1 - 6e-32 111.0 9.1 7.9e-32 110.6 9.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF1761 PF08570.10 EGO59720.1 - 0.7 10.2 6.1 1.7 8.9 6.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1761) DSPc PF00782.20 EGO59721.1 - 3.2e-09 36.7 0.0 6.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGO59721.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pribosyltran_N PF13793.6 EGO59722.1 - 5.2e-42 142.5 0.1 1.7e-41 140.8 0.1 1.9 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGO59722.1 - 5.3e-41 140.7 1.5 1e-35 123.4 0.3 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGO59722.1 - 8.7e-15 54.6 0.3 1.9e-14 53.5 0.3 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGO59722.1 - 0.0033 16.9 0.1 0.0069 15.9 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Fungal_trans PF04082.18 EGO59723.1 - 7.3e-30 103.9 0.0 2e-29 102.4 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO59723.1 - 2.6e-09 37.0 7.6 4.3e-09 36.4 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynamin_N PF00350.23 EGO59724.1 - 5e-18 65.7 0.0 2.1e-13 50.6 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Dynamin_M PF01031.20 EGO59724.1 - 6.8e-18 64.9 0.0 1.3e-16 60.7 0.0 2.6 2 1 0 2 2 2 1 Dynamin central region GED PF02212.18 EGO59724.1 - 3e-06 27.3 0.1 7.6e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain AAA_28 PF13521.6 EGO59724.1 - 0.0072 16.6 0.1 0.03 14.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EGO59724.1 - 0.012 15.7 0.0 0.046 13.8 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO59724.1 - 0.012 15.5 0.3 0.85 9.5 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 EGO59724.1 - 0.015 15.1 1.2 0.043 13.5 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain FAA_hydrolase_N PF09298.11 EGO59724.1 - 0.032 14.4 0.1 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal D5_N PF08706.11 EGO59724.1 - 0.04 14.2 0.3 0.43 10.8 0.2 2.4 2 0 0 2 2 2 0 D5 N terminal like PduV-EutP PF10662.9 EGO59724.1 - 0.044 13.5 0.5 12 5.7 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EGO59724.1 - 0.05 14.1 0.0 0.14 12.6 0.0 2.0 1 1 0 1 1 1 0 ABC transporter THOC7 PF05615.13 EGO59724.1 - 0.5 10.6 2.7 0.59 10.4 0.5 2.3 2 1 0 2 2 2 0 Tho complex subunit 7 PHP PF02811.19 EGO59725.1 - 5.6e-12 46.3 0.0 9e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 PHP domain DHC_N1 PF08385.12 EGO59726.1 - 7.1e-125 417.8 5.9 7.1e-125 417.8 5.9 5.0 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EGO59726.1 - 5.3e-116 388.0 9.5 5.3e-116 388.0 9.5 5.0 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 EGO59726.1 - 1e-109 366.5 0.0 5.2e-109 364.2 0.0 2.3 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region AAA_9 PF12781.7 EGO59726.1 - 1.4e-73 246.6 1.3 1.4e-73 246.6 1.3 3.2 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 EGO59726.1 - 2.6e-65 220.3 0.0 1.7e-64 217.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EGO59726.1 - 2.4e-41 141.3 0.0 9.8e-36 123.0 0.0 4.3 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 EGO59726.1 - 2.2e-37 128.9 8.4 2.2e-37 128.9 8.4 2.1 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EGO59726.1 - 4.9e-31 107.6 0.0 4.4e-12 46.2 0.0 5.8 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 EGO59726.1 - 6.8e-31 107.3 0.0 1.7e-30 106.0 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGO59726.1 - 1.2e-29 102.8 0.1 4.3e-26 91.3 0.0 4.5 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 EGO59726.1 - 3.8e-16 59.6 0.4 0.0096 16.2 0.0 6.4 5 0 0 5 5 5 3 AAA domain Dynein_AAA_lid PF17852.1 EGO59726.1 - 1.6e-15 57.3 0.0 5.4e-15 55.6 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 EGO59726.1 - 2.2e-13 50.8 0.0 0.0023 18.3 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGO59726.1 - 8.4e-13 49.1 0.0 0.59 10.5 0.0 7.7 6 0 0 6 6 6 2 AAA ATPase domain AAA_33 PF13671.6 EGO59726.1 - 6.9e-10 39.2 0.6 0.28 11.4 0.0 5.1 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.6 EGO59726.1 - 1.4e-09 38.6 0.4 0.08 13.5 0.0 5.4 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 EGO59726.1 - 4.2e-06 26.0 0.0 0.028 13.5 0.0 3.6 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_lid_1 PF17857.1 EGO59726.1 - 7.5e-06 26.1 0.0 0.00038 20.6 0.0 3.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_29 PF13555.6 EGO59726.1 - 1.6e-05 24.5 0.1 1.2 9.0 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EGO59726.1 - 5.4e-05 22.7 0.8 0.67 9.3 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EGO59726.1 - 7.2e-05 23.3 0.1 4.7 7.7 0.0 5.0 3 0 0 3 3 3 0 ABC transporter AAA_19 PF13245.6 EGO59726.1 - 0.00073 19.9 1.4 0.28 11.5 0.0 4.4 5 0 0 5 5 3 1 AAA domain AAA_30 PF13604.6 EGO59726.1 - 0.00093 19.0 0.2 39 3.9 0.0 4.7 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.18 EGO59726.1 - 0.00098 18.5 1.2 2.4 7.5 0.0 4.0 4 0 0 4 4 3 1 FtsK/SpoIIIE family AAA_24 PF13479.6 EGO59726.1 - 0.0017 18.1 3.6 11 5.7 0.0 5.4 6 1 0 6 6 4 0 AAA domain AAA_25 PF13481.6 EGO59726.1 - 0.0023 17.5 1.4 0.24 11.0 0.0 3.7 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 EGO59726.1 - 0.0031 16.8 0.0 1.4 8.2 0.0 3.8 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.22 EGO59726.1 - 0.0035 17.7 0.0 24 5.4 0.0 4.5 4 0 0 4 4 4 0 RNA helicase IstB_IS21 PF01695.17 EGO59726.1 - 0.0048 16.7 0.3 0.7 9.6 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein Rad17 PF03215.15 EGO59726.1 - 0.01 15.7 0.9 6.8 6.6 0.0 4.4 5 0 0 5 5 4 0 Rad17 P-loop domain RuvB_N PF05496.12 EGO59726.1 - 0.056 13.2 0.0 5.3 6.8 0.0 3.7 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain COG2 PF06148.11 EGO59726.1 - 0.067 13.3 0.1 0.067 13.3 0.1 5.8 7 0 0 7 7 4 0 COG (conserved oligomeric Golgi) complex component, COG2 NACHT PF05729.12 EGO59726.1 - 0.097 12.6 3.7 31 4.4 0.0 4.5 5 0 0 5 5 3 0 NACHT domain NTPase_1 PF03266.15 EGO59726.1 - 0.13 12.2 0.7 39 4.1 0.0 4.0 4 0 0 4 4 3 0 NTPase UCH PF00443.29 EGO59726.1 - 0.16 11.4 0.2 65 2.9 0.1 3.8 3 1 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase MMR_HSR1 PF01926.23 EGO59726.1 - 0.22 11.6 0.5 26 4.9 0.0 4.2 4 0 0 4 4 4 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGO59726.1 - 0.89 9.3 3.9 11 5.7 0.1 4.2 5 0 0 5 5 5 0 Ethanolamine utilisation - propanediol utilisation DUF4482 PF14818.6 EGO59726.1 - 1.1 10.1 11.6 38 5.1 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) LOH1CR12 PF10158.9 EGO59726.1 - 8.2 6.5 16.5 1.7 8.7 0.7 5.4 4 0 0 4 4 3 0 Tumour suppressor protein DUF1774 PF08611.10 EGO59728.1 - 5.2e-39 132.5 5.5 5.2e-39 132.5 5.5 2.5 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) ACPS PF01648.20 EGO59729.1 - 0.00057 20.0 0.2 0.0014 18.7 0.1 1.7 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EGO59729.1 - 0.02 15.0 0.8 7.7 6.7 0.1 2.4 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain Menin PF05053.13 EGO59729.1 - 0.041 12.3 6.0 0.051 11.9 6.0 1.2 1 0 0 1 1 1 0 Menin Macoilin PF09726.9 EGO59729.1 - 1.2 7.7 6.2 1.4 7.4 6.2 1.2 1 0 0 1 1 1 0 Macoilin family CCSAP PF15748.5 EGO59729.1 - 2.2 8.4 9.8 0.69 10.0 7.2 1.5 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated MAP70 PF07058.11 EGO59729.1 - 3.4 6.3 6.1 4.4 5.9 6.1 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 Presenilin PF01080.17 EGO59729.1 - 7.2 5.3 6.5 9.7 4.8 6.5 1.1 1 0 0 1 1 1 0 Presenilin Secretin_N_2 PF07655.13 EGO59729.1 - 7.2 7.2 27.2 3.2 8.4 13.7 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain CAP_N PF01213.19 EGO59730.1 - 9.2 5.6 5.6 13 5.2 5.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Dynamin_N PF00350.23 EGO59731.1 - 3.5e-15 56.5 6.5 5.6e-15 55.8 0.0 3.7 2 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 EGO59731.1 - 3.3e-05 24.0 0.0 0.0019 18.3 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGO59731.1 - 0.0014 19.1 2.6 0.051 14.0 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 EGO59731.1 - 0.0079 16.7 2.7 0.016 15.7 0.0 2.8 3 0 0 3 3 3 1 ABC transporter Mod_r PF07200.13 EGO59731.1 - 0.0098 16.0 5.4 0.0098 16.0 5.4 5.3 7 1 0 7 7 6 1 Modifier of rudimentary (Mod(r)) protein AAA_22 PF13401.6 EGO59731.1 - 0.026 14.8 0.3 0.25 11.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 EGO59731.1 - 0.032 13.5 0.0 0.1 11.9 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 EGO59731.1 - 0.093 12.6 1.2 0.39 10.6 0.0 2.7 4 0 0 4 4 4 0 RsgA GTPase EF1_GNE PF00736.19 EGO59731.1 - 0.26 11.5 3.9 0.15 12.3 0.3 2.5 2 0 0 2 2 2 0 EF-1 guanine nucleotide exchange domain YabA PF06156.13 EGO59731.1 - 1.1 10.0 17.4 7.9 7.2 2.7 4.0 3 0 0 3 3 3 0 Initiation control protein YabA Laminin_II PF06009.12 EGO59731.1 - 2 8.4 10.5 0.83 9.7 1.2 3.1 3 0 0 3 3 3 0 Laminin Domain II DUF3837 PF12939.7 EGO59731.1 - 3.4 8.1 6.0 1.3 9.4 1.0 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF3837) Ax_dynein_light PF10211.9 EGO59731.1 - 4.4 7.2 15.3 12 5.8 7.1 3.1 3 0 0 3 3 3 0 Axonemal dynein light chain APG6_N PF17675.1 EGO59731.1 - 6.3 7.3 29.6 0.24 11.9 7.1 3.3 3 0 0 3 3 3 0 Apg6 coiled-coil region WSC PF01822.19 EGO59733.1 - 8.1e-10 38.8 9.5 8.1e-10 38.8 9.5 2.0 2 0 0 2 2 2 1 WSC domain Stevor PF17410.2 EGO59733.1 - 4.3e-05 23.2 0.1 4.3e-05 23.2 0.1 2.1 1 1 1 2 2 2 1 Subtelomeric Variable Open Reading frame Podoplanin PF05808.11 EGO59733.1 - 0.0083 16.2 8.8 0.0083 16.2 8.8 2.3 1 1 1 2 2 2 1 Podoplanin DUF347 PF03988.12 EGO59733.1 - 0.013 15.6 0.2 0.035 14.3 0.2 1.8 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Rax2 PF12768.7 EGO59733.1 - 0.014 14.8 0.1 0.031 13.7 0.1 1.6 1 1 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.10 EGO59733.1 - 0.018 14.4 1.5 0.089 12.2 1.5 2.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Phage_holin_3_6 PF07332.11 EGO59733.1 - 0.084 12.9 0.1 0.084 12.9 0.1 1.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4366 PF14283.6 EGO59733.1 - 0.61 10.1 0.0 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) SUZ PF12752.7 EGO59733.1 - 3.5 8.5 4.8 3.4 8.5 0.2 2.6 2 0 0 2 2 2 0 SUZ domain YajC PF02699.15 EGO59736.1 - 2.1e-05 24.3 0.0 0.0013 18.5 0.0 2.4 2 0 0 2 2 2 1 Preprotein translocase subunit SKG6 PF08693.10 EGO59736.1 - 0.002 17.5 0.1 0.0059 16.0 0.1 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LapA_dom PF06305.11 EGO59736.1 - 0.019 14.8 1.0 0.042 13.7 1.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4381 PF14316.6 EGO59736.1 - 0.13 12.5 2.0 0.18 12.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) ZapB PF06005.12 EGO59737.1 - 0.0029 18.0 18.0 0.013 15.9 4.3 3.2 3 0 0 3 3 3 1 Cell division protein ZapB ATG16 PF08614.11 EGO59737.1 - 0.0096 16.2 11.5 1.2 9.3 12.4 2.7 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) SHE3 PF17078.5 EGO59737.1 - 0.014 15.1 7.0 0.033 13.9 7.0 1.6 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 HAUS-augmin3 PF14932.6 EGO59737.1 - 0.022 14.4 13.4 0.05 13.2 13.4 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 AAA_11 PF13086.6 EGO59737.1 - 0.19 11.5 4.2 0.31 10.8 4.2 1.2 1 0 0 1 1 1 0 AAA domain GAS PF13851.6 EGO59737.1 - 0.2 11.0 19.5 0.97 8.7 7.4 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 EGO59737.1 - 0.26 10.3 8.5 0.47 9.5 8.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LtuB PF17455.2 EGO59737.1 - 0.35 11.5 5.2 0.2 12.3 0.4 2.9 3 0 0 3 3 2 0 Late transcription unit B TMF_DNA_bd PF12329.8 EGO59737.1 - 0.69 10.0 14.8 1.1 9.3 13.6 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 EGO59737.1 - 1.2 9.1 19.6 4.1 7.4 8.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 EGO59737.1 - 1.5 8.9 10.5 1.1 9.4 3.0 3.1 2 0 0 2 2 2 0 TolA binding protein trimerisation TMPIT PF07851.13 EGO59737.1 - 1.6 7.9 6.9 2.5 7.3 6.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 EGO59737.1 - 2.5 7.4 9.1 1.8 7.9 7.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) STAT_alpha PF01017.20 EGO59737.1 - 2.6 7.9 8.8 4.2 7.2 7.8 1.9 2 0 0 2 2 2 0 STAT protein, all-alpha domain DivIC PF04977.15 EGO59737.1 - 2.8 7.8 15.8 0.64 9.8 2.2 3.1 3 0 0 3 3 2 0 Septum formation initiator DUF5082 PF16888.5 EGO59737.1 - 3.1 8.1 11.3 5.3 7.3 0.4 2.9 2 1 1 3 3 2 0 Domain of unknown function (DUF5082) DUF3450 PF11932.8 EGO59737.1 - 3.1 7.0 15.3 4 6.7 2.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF883 PF05957.13 EGO59737.1 - 4 8.1 7.7 8.3 7.1 6.7 2.2 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF883) V_ATPase_I PF01496.19 EGO59737.1 - 5.1 4.9 6.0 7.4 4.4 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 EGO59737.1 - 9.3 5.0 17.3 43 2.9 17.9 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein FCH PF00611.23 EGO59737.1 - 9.6 6.6 9.6 17 5.8 1.9 3.1 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain RSN1_7TM PF02714.15 EGO59738.1 - 4.6e-87 291.8 24.7 4.6e-87 291.8 24.7 2.1 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGO59738.1 - 2e-47 160.9 3.2 2e-47 160.9 3.2 3.3 4 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGO59738.1 - 1.8e-36 126.0 0.0 2.9e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EGO59738.1 - 1.6e-30 105.1 0.0 3.4e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Colicin_V PF02674.16 EGO59738.1 - 0.0037 17.2 6.2 0.0037 17.2 6.2 3.5 3 1 1 4 4 4 1 Colicin V production protein kleA_kleC PF17383.2 EGO59738.1 - 0.16 12.3 0.4 0.36 11.2 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Solute_trans_a PF03619.16 EGO59739.1 - 4.3e-87 292.0 23.0 5.1e-87 291.8 23.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Orf78 PF06024.12 EGO59739.1 - 0.98 9.7 4.2 2.7 8.3 0.1 2.9 3 0 0 3 3 3 0 Orf78 (ac78) ABA_GPCR PF12430.8 EGO59739.1 - 2.6 7.8 7.8 0.42 10.3 1.7 2.1 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor Polysacc_synt_C PF14667.6 EGO59739.1 - 5.1 7.2 15.3 4.1 7.5 3.8 2.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain GCP_N_terminal PF17681.1 EGO59740.1 - 1.5e-28 100.3 0.1 2.8e-28 99.5 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGO59740.1 - 8.3e-16 58.3 1.1 2.2e-14 53.7 1.1 2.8 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal Senescence PF06911.12 EGO59741.1 - 9e-57 192.3 0.2 1.3e-56 191.8 0.2 1.3 1 0 0 1 1 1 1 Senescence-associated protein Fungal_trans PF04082.18 EGO59742.1 - 5.9e-19 68.1 0.0 1.1e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SMC_Nse1 PF07574.13 EGO59744.1 - 4.2e-64 216.0 0.0 5.4e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EGO59744.1 - 1.5e-15 57.2 8.8 2.2e-15 56.7 8.8 1.3 1 0 0 1 1 1 1 RING-like domain FYDLN_acid PF09538.10 EGO59744.1 - 0.011 16.3 2.0 0.022 15.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PaaX PF07848.12 EGO59744.1 - 0.14 12.4 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 PaaX-like protein HTH_IclR PF09339.10 EGO59744.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain zf-HC5HC2H PF13771.6 EGO59744.1 - 0.39 11.0 5.2 1 9.6 5.2 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-ANAPC11 PF12861.7 EGO59744.1 - 0.84 9.7 4.5 1.4 9.0 4.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-tcix PF14952.6 EGO59744.1 - 1.2 8.8 4.9 0.27 10.9 0.4 2.1 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding zf-RING_2 PF13639.6 EGO59744.1 - 2.9 8.3 7.8 4.5 7.7 7.8 1.3 1 0 0 1 1 1 0 Ring finger domain C1_1 PF00130.22 EGO59744.1 - 4.5 7.2 9.3 0.49 10.3 3.5 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SPRY PF00622.28 EGO59746.1 - 1e-05 25.6 0.0 0.0008 19.5 0.0 3.0 3 0 0 3 3 3 1 SPRY domain Myb_Cef PF11831.8 EGO59747.1 - 1.4e-52 178.7 9.4 1.4e-52 178.7 9.4 2.7 2 0 0 2 2 2 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EGO59747.1 - 1.7e-22 79.4 5.0 8.5e-11 41.9 0.9 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO59747.1 - 5e-22 77.9 7.3 7.3e-15 55.0 2.7 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Golgin_A5 PF09787.9 EGO59747.1 - 0.005 16.3 2.5 0.005 16.3 2.5 3.0 3 0 0 3 3 3 1 Golgin subfamily A member 5 Rap1_C PF11626.8 EGO59747.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.5 4 0 0 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Pox_Ag35 PF03286.14 EGO59748.1 - 0.018 14.9 0.9 0.025 14.4 0.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3306 PF11748.8 EGO59748.1 - 0.31 11.9 4.1 5.1 8.0 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Nucleo_P87 PF07267.11 EGO59748.1 - 0.65 8.8 2.1 0.82 8.4 2.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FAM176 PF14851.6 EGO59748.1 - 1.3 8.6 4.8 2.4 7.8 4.8 1.4 1 0 0 1 1 1 0 FAM176 family Hexokinase_2 PF03727.16 EGO59749.1 - 1.9e-49 168.2 0.0 4.8e-49 167.0 0.0 1.6 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 EGO59749.1 - 3.5e-48 164.2 0.0 5.6e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase GILT PF03227.16 EGO59750.1 - 1.6e-18 66.9 0.1 2.9e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) VASt PF16016.5 EGO59751.1 - 6.5e-41 140.3 0.0 1.1e-40 139.6 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EGO59751.1 - 3.7e-24 84.8 0.0 7e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 GRAM domain MPS2 PF17060.5 EGO59752.1 - 0.0031 16.8 0.1 0.0051 16.1 0.1 1.2 1 0 0 1 1 1 1 Monopolar spindle protein 2 bZIP_1 PF00170.21 EGO59752.1 - 0.0043 17.1 5.8 0.99 9.6 2.6 2.7 2 0 0 2 2 2 2 bZIP transcription factor Ax_dynein_light PF10211.9 EGO59752.1 - 0.0064 16.5 8.7 1.1 9.1 4.2 2.4 2 0 0 2 2 2 2 Axonemal dynein light chain KASH_CCD PF14662.6 EGO59752.1 - 0.0076 16.1 9.8 0.22 11.3 3.6 2.4 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH Tsc35 PF15079.6 EGO59752.1 - 0.014 15.0 3.1 0.02 14.5 0.8 2.0 2 0 0 2 2 2 0 Testis-specific protein 35 DUF812 PF05667.11 EGO59752.1 - 0.041 12.8 7.1 0.0058 15.6 3.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) YabA PF06156.13 EGO59752.1 - 0.043 14.5 5.2 0.5 11.0 1.2 2.6 2 0 0 2 2 2 0 Initiation control protein YabA Tropomyosin_1 PF12718.7 EGO59752.1 - 0.047 13.8 7.3 0.43 10.7 3.0 2.5 2 0 0 2 2 2 0 Tropomyosin like SHE3 PF17078.5 EGO59752.1 - 0.05 13.3 5.7 0.21 11.2 1.7 2.3 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4515 PF14988.6 EGO59752.1 - 0.066 13.0 5.1 0.066 13.1 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) Leu_zip PF15294.6 EGO59752.1 - 0.069 12.7 3.1 0.37 10.3 0.6 2.2 2 0 0 2 2 2 0 Leucine zipper Cnn_1N PF07989.11 EGO59752.1 - 0.089 13.0 5.7 1.8 8.7 1.4 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 TMF_DNA_bd PF12329.8 EGO59752.1 - 0.29 11.2 7.2 0.8 9.7 1.9 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.6 EGO59752.1 - 0.34 10.5 9.7 3.4 7.3 4.5 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease KIAA1430 PF13879.6 EGO59752.1 - 0.37 11.6 4.1 7.6 7.4 1.1 2.8 2 0 0 2 2 2 0 KIAA1430 homologue CENP-Q PF13094.6 EGO59752.1 - 0.55 10.4 21.6 0.025 14.8 4.8 3.8 3 1 1 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4200 PF13863.6 EGO59752.1 - 0.57 10.6 7.9 3.2 8.2 3.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Sec34 PF04136.15 EGO59752.1 - 0.58 10.0 3.2 5.8 6.8 0.2 2.4 2 0 0 2 2 2 0 Sec34-like family Tektin PF03148.14 EGO59752.1 - 0.69 8.6 7.1 0.71 8.6 2.3 2.2 2 0 0 2 2 2 0 Tektin family Fez1 PF06818.15 EGO59752.1 - 0.75 10.2 11.7 0.15 12.5 3.2 2.6 3 0 0 3 3 2 0 Fez1 GAS PF13851.6 EGO59752.1 - 1.1 8.6 13.9 1.9 7.8 7.6 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 EGO59752.1 - 1.2 9.7 13.7 9.1 6.8 0.2 3.2 2 1 0 2 2 2 0 Cell division protein ZapB Macoilin PF09726.9 EGO59752.1 - 1.2 7.6 13.2 0.0085 14.7 2.8 2.1 2 1 0 2 2 2 0 Macoilin family FlaC_arch PF05377.11 EGO59752.1 - 1.4 9.4 5.7 1.8 9.0 1.2 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4201 PF13870.6 EGO59752.1 - 1.4 8.6 10.1 0.77 9.5 4.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TSC22 PF01166.18 EGO59752.1 - 1.6 9.1 5.8 23 5.4 0.2 2.6 2 1 0 2 2 2 0 TSC-22/dip/bun family Prefoldin_2 PF01920.20 EGO59752.1 - 1.8 8.6 6.6 3.2 7.7 2.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit DivIVA PF05103.13 EGO59752.1 - 2.1 8.5 18.1 0.27 11.3 4.3 2.7 3 0 0 3 3 2 0 DivIVA protein SOGA PF11365.8 EGO59752.1 - 3.7 8.7 10.9 2.8 9.1 2.2 3.3 3 0 0 3 3 3 0 Protein SOGA Spc7 PF08317.11 EGO59752.1 - 4.7 6.0 8.8 0.82 8.5 3.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 EGO59752.1 - 5 7.7 6.4 8.8 7.0 0.2 3.4 4 0 0 4 4 4 0 Syntaxin 6, N-terminal ABC_tran_CTD PF16326.5 EGO59752.1 - 5.5 7.3 13.8 0.15 12.3 5.7 2.5 3 0 0 3 3 2 0 ABC transporter C-terminal domain Jnk-SapK_ap_N PF09744.9 EGO59752.1 - 5.8 7.1 10.1 7.9 6.7 3.8 2.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Fmp27_WPPW PF10359.9 EGO59752.1 - 6.5 5.5 7.8 0.89 8.3 0.4 2.6 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain MIT PF04212.18 EGO59752.1 - 6.9 6.8 6.9 1.6 8.8 0.9 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain KxDL PF10241.9 EGO59752.1 - 7 7.0 7.6 21 5.5 1.7 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein TolA_bind_tri PF16331.5 EGO59752.1 - 7.6 6.7 11.0 1.6 8.8 3.9 2.7 3 0 0 3 3 2 0 TolA binding protein trimerisation Abhydrolase_1 PF00561.20 EGO59753.1 - 2.7e-49 168.1 0.0 5.7e-49 167.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO59753.1 - 0.027 15.1 7.6 0.061 13.9 7.6 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family THOC2_N PF16134.5 EGO59754.1 - 1.3e-227 757.5 0.0 9.5e-128 427.6 0.0 2.3 1 1 1 2 2 2 2 THO complex subunit 2 N-terminus Tho2 PF11262.8 EGO59754.1 - 7.9e-99 330.6 5.2 1.1e-98 330.2 5.2 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EGO59754.1 - 5.4e-28 96.9 0.1 1.3e-27 95.7 0.1 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit TFCD_C PF12612.8 EGO59755.1 - 3.4e-26 92.3 3.8 4.9e-24 85.2 3.8 2.6 1 1 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 EGO59755.1 - 0.00033 20.7 3.1 0.1 12.9 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 EGO59755.1 - 0.042 13.9 0.9 1.3 9.0 0.1 3.6 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGO59755.1 - 0.29 11.7 1.7 1.9 9.1 0.0 3.2 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Glyco_hydro_76 PF03663.14 EGO59756.1 - 4.5e-42 144.9 4.9 4.5e-42 144.9 4.9 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EGO59756.1 - 2.4e-06 26.9 0.3 0.00057 19.1 0.0 2.7 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Fungal_trans PF04082.18 EGO59757.1 - 1.4e-17 63.6 3.6 2.4e-17 62.8 3.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO59757.1 - 2.7e-09 37.0 9.3 2.7e-09 37.0 9.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF326 PF03860.16 EGO59757.1 - 1.6 8.8 5.4 3 8.0 5.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF326) RPE65 PF03055.15 EGO59758.1 - 1.3e-111 374.1 0.0 1.5e-111 373.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein C1_2 PF03107.16 EGO59759.1 - 0.0031 17.8 8.7 0.004 17.4 8.7 1.2 1 0 0 1 1 1 1 C1 domain zinc_ribbon_10 PF10058.9 EGO59759.1 - 0.084 12.6 5.6 0.14 11.9 0.1 2.3 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein His_Phos_2 PF00328.22 EGO59761.1 - 1.1e-109 367.4 0.0 1.5e-109 366.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EGO59761.1 - 2.8e-36 123.5 0.0 5.9e-36 122.5 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EGO59761.1 - 3.1e-08 33.4 0.0 6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DUF1754 PF08555.10 EGO59761.1 - 4.8 8.0 10.8 1.4 9.7 4.6 3.0 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Utp21 PF04192.12 EGO59762.1 - 3.3e-85 285.3 0.2 5e-85 284.7 0.2 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 EGO59762.1 - 5.3e-19 68.2 24.4 2.5e-05 24.9 0.5 10.2 10 0 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO59762.1 - 1.1e-12 48.1 0.0 0.0046 17.2 0.0 6.2 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO59762.1 - 9.1e-07 27.9 1.4 0.96 8.0 0.1 4.1 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EGO59762.1 - 0.00036 19.2 0.0 0.00077 18.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 EGO59762.1 - 0.045 12.5 0.2 4.5 5.9 0.1 2.3 1 1 0 2 2 2 0 Nup133 N terminal like VID27 PF08553.10 EGO59762.1 - 0.19 10.7 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain SH3_1 PF00018.28 EGO59763.1 - 3.4e-09 36.2 0.2 8.3e-09 34.9 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGO59763.1 - 1.2e-07 31.3 0.0 2.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGO59763.1 - 3.1e-07 30.1 0.2 6.6e-07 29.1 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain DNA_pol_phi PF04931.13 EGO59763.1 - 1.8 6.6 18.6 3.9 5.5 18.6 1.5 1 0 0 1 1 1 0 DNA polymerase phi RPAP2_Rtr1 PF04181.13 EGO59764.1 - 5.7e-20 71.4 0.5 1.2e-19 70.4 0.5 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family Spore_III_AF PF09581.10 EGO59764.1 - 2.7 8.0 6.0 4.1 7.4 6.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Ribosomal_S17e PF00833.18 EGO59765.1 - 6.8e-60 200.4 0.4 8.5e-60 200.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal S17 GUCT PF08152.12 EGO59765.1 - 0.16 12.3 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 GUCT (NUC152) domain Mit_ribos_Mrp51 PF11709.8 EGO59766.1 - 6.6e-124 414.2 0.0 7.6e-124 414.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit TGT PF01702.18 EGO59767.1 - 2.3e-139 464.4 0.0 2.8e-139 464.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase PUMA PF15826.5 EGO59768.1 - 0.0076 16.4 0.2 0.016 15.4 0.2 1.6 1 1 0 1 1 1 1 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Hist_deacetyl PF00850.19 EGO59770.1 - 3e-53 181.3 0.1 4.8e-53 180.6 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.21 EGO59771.1 - 7.5e-10 38.8 0.2 2e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGO59771.1 - 3.8e-09 37.0 2.0 9.5e-09 35.7 2.0 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function PLU-1 PF08429.11 EGO59771.1 - 0.96 8.6 5.1 5.6 6.0 0.8 2.1 1 1 0 2 2 2 0 PLU-1-like protein Vps5 PF09325.10 EGO59772.1 - 3.2e-12 46.5 1.2 7.1e-12 45.4 1.2 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EGO59772.1 - 3.2e-08 33.5 0.0 6.6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 PX domain TFIIA PF03153.13 EGO59772.1 - 0.21 11.6 28.3 0.022 14.8 22.5 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit GTP_EFTU PF00009.27 EGO59773.1 - 5.3e-37 127.2 0.0 1.7e-36 125.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EGO59773.1 - 9.5e-23 80.1 0.1 6e-22 77.5 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 EGO59773.1 - 8.1e-11 41.8 0.0 0.00082 19.4 0.0 2.8 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGO59773.1 - 0.00058 20.2 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EGO59773.1 - 0.00096 19.0 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain ADH_N PF08240.12 EGO59774.1 - 4.4e-26 90.9 2.0 8.5e-26 90.0 2.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO59774.1 - 9.5e-16 58.0 0.1 4.3e-11 42.9 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGO59774.1 - 4.4e-10 39.4 0.3 0.00021 20.8 0.0 2.5 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EGO59774.1 - 0.0013 18.0 0.2 0.0024 17.2 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EGO59774.1 - 0.0022 17.6 0.8 0.0048 16.5 0.2 1.8 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NADH_4Fe-4S PF10589.9 EGO59774.1 - 0.04 14.0 0.6 0.15 12.2 0.6 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region ADH_zinc_N_2 PF13602.6 EGO59774.1 - 0.041 14.9 0.0 0.085 13.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_8 PF13450.6 EGO59774.1 - 0.049 13.9 0.1 0.2 11.9 0.1 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 EGO59774.1 - 0.078 12.3 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.18 EGO59774.1 - 0.086 12.7 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EGO59774.1 - 0.12 13.1 0.2 1.7 9.4 0.1 2.4 2 0 0 2 2 2 0 Methyltransferase domain Avl9 PF09794.9 EGO59775.1 - 5.3e-142 473.0 0.0 7.2e-142 472.6 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 EGO59775.1 - 1.4e-06 28.2 1.1 2.5e-05 24.0 0.0 3.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 EGO59775.1 - 1e-05 25.5 0.0 0.00042 20.3 0.0 2.3 2 0 0 2 2 2 1 Stabilization of polarity axis LAT PF15234.6 EGO59775.1 - 0.95 9.2 9.2 0.046 13.5 3.2 1.8 2 0 0 2 2 2 0 Linker for activation of T-cells Pkinase PF00069.25 EGO59776.1 - 1.5e-68 231.0 0.0 1.9e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO59776.1 - 3.7e-32 111.6 0.0 5.2e-32 111.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO59776.1 - 8.8e-06 24.9 0.1 1.2e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGO59776.1 - 2.7e-05 23.6 0.1 8.5e-05 22.0 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO59776.1 - 0.0005 20.1 0.1 0.0017 18.3 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGO59776.1 - 0.0015 17.9 0.0 0.056 12.7 0.0 2.2 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 EGO59776.1 - 0.024 14.3 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EGO59776.1 - 0.024 14.2 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Get5_C PF18514.1 EGO59776.1 - 0.19 11.5 0.1 0.43 10.3 0.1 1.6 1 0 0 1 1 1 0 Get5 C-terminal domain Phosphorylase PF00343.20 EGO59779.1 - 0 1058.9 0.0 0 1058.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Ribonuclease_T2 PF00445.18 EGO59781.1 - 1.1e-13 51.8 0.0 2.4e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease T2 family FAD_binding_4 PF01565.23 EGO59781.1 - 2.3e-13 50.1 0.0 4.3e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGO59781.1 - 7.9e-07 29.1 0.0 1.9e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like GMC_oxred_C PF05199.13 EGO59782.1 - 9.9e-14 52.1 0.2 2.2e-13 50.9 0.2 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Ank_4 PF13637.6 EGO59784.1 - 4.4e-31 106.9 4.9 4.9e-06 27.0 0.1 8.4 7 2 2 9 9 9 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO59784.1 - 2.5e-28 98.5 3.4 1.6e-05 25.4 0.1 6.9 4 1 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO59784.1 - 1.3e-19 68.2 1.5 0.00064 20.0 0.0 11.2 12 1 0 12 12 12 3 Ankyrin repeat Ank_5 PF13857.6 EGO59784.1 - 1.6e-18 66.5 9.1 0.0004 20.6 0.1 8.1 6 3 3 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 EGO59784.1 - 1.7e-16 59.8 11.7 0.15 12.6 0.0 9.9 10 1 1 11 11 11 5 Ankyrin repeat DNA_pol_A_exo1 PF01612.20 EGO59785.1 - 1.7e-08 34.4 0.0 2.1e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease Ank_2 PF12796.7 EGO59786.1 - 2.7e-07 31.1 0.0 1.9e-06 28.4 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO59786.1 - 4.7e-05 23.9 0.0 0.0014 19.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO59786.1 - 0.00023 21.4 0.0 0.0006 20.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO59786.1 - 0.00042 20.5 0.0 0.04 14.5 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EGO59786.1 - 0.00045 20.5 0.0 0.11 13.0 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat GATA PF00320.27 EGO59788.1 - 1.2e-14 53.5 2.5 2.2e-14 52.7 2.5 1.4 1 0 0 1 1 1 1 GATA zinc finger ATG16 PF08614.11 EGO59788.1 - 0.0045 17.2 12.4 0.0045 17.2 12.4 3.8 3 1 1 4 4 3 1 Autophagy protein 16 (ATG16) DUF2387 PF09526.10 EGO59788.1 - 0.037 14.2 0.1 0.037 14.2 0.1 2.5 3 0 0 3 3 2 0 Probable metal-binding protein (DUF2387) FapA PF03961.13 EGO59788.1 - 0.064 11.8 6.5 0.1 11.2 6.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A JIP_LZII PF16471.5 EGO59788.1 - 1.1 9.4 11.6 0.68 10.1 5.3 2.4 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Phage_GPO PF05929.11 EGO59788.1 - 1.9 8.0 6.4 1.3 8.6 3.9 2.0 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase LMBR1 PF04791.16 EGO59788.1 - 2.1 7.2 8.1 11 4.7 8.1 2.0 1 1 0 1 1 1 0 LMBR1-like membrane protein TMPIT PF07851.13 EGO59788.1 - 2.5 7.3 4.3 4.7 6.4 4.3 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 EGO59788.1 - 4.1 6.7 6.8 11 5.3 3.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 EGO59788.1 - 6.8 5.7 12.9 1.5 7.8 8.3 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4226 PF10774.9 EGO59788.1 - 7.6 6.9 12.5 0.086 13.1 4.4 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4226) KH_8 PF17903.1 EGO59789.1 - 2.5e-29 101.2 0.0 6e-29 100.0 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EGO59789.1 - 0.034 14.0 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 KH domain ADH_zinc_N PF00107.26 EGO59790.1 - 2.4e-21 76.1 0.4 3.8e-21 75.4 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO59790.1 - 2.4e-09 38.4 0.1 3.9e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EGO59790.1 - 7.5e-05 22.3 0.2 0.00011 21.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.12 EGO59790.1 - 0.00078 19.3 0.0 0.0018 18.1 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EGO59790.1 - 0.0098 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PA PF02225.22 EGO59790.1 - 0.096 12.7 0.2 0.21 11.7 0.2 1.7 1 0 0 1 1 1 0 PA domain SWIM PF04434.17 EGO59791.1 - 0.062 13.0 3.9 0.16 11.7 3.9 1.7 1 0 0 1 1 1 0 SWIM zinc finger Lactamase_B PF00753.27 EGO59792.1 - 6.1e-15 55.8 0.1 8.6e-15 55.3 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Transposase_21 PF02992.14 EGO59792.1 - 0.022 14.0 0.0 0.043 13.1 0.0 1.4 2 0 0 2 2 2 0 Transposase family tnp2 Lactamase_B_2 PF12706.7 EGO59792.1 - 0.11 12.0 0.6 0.3 10.6 0.6 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Sulf_transp PF04143.14 EGO59793.1 - 1.5e-32 113.4 26.4 2.8e-32 112.5 26.4 1.4 1 1 0 1 1 1 1 Sulphur transport Prok-RING_2 PF14445.6 EGO59794.1 - 0.053 13.7 6.7 0.12 12.5 6.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 S1 PF00575.23 EGO59794.1 - 0.18 12.2 2.0 0.34 11.3 2.0 1.5 1 0 0 1 1 1 0 S1 RNA binding domain Zf_RING PF16744.5 EGO59794.1 - 2 8.6 11.9 4.1 7.6 11.9 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 EGO59794.1 - 2.9 7.6 14.6 5.2 6.8 14.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF3979 PF13141.6 EGO59796.1 - 0.0053 17.0 0.2 0.0068 16.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3979) MNE1 PF13762.6 EGO59797.1 - 0.097 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component Ysc84 PF04366.12 EGO59798.1 - 1.8e-32 111.8 0.0 2.8e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator TrkA_TMD PF18613.1 EGO59798.1 - 0.19 11.2 0.8 0.33 10.4 0.8 1.3 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain Importin_rep_6 PF18829.1 EGO59798.1 - 0.2 11.8 1.2 0.39 10.9 1.2 1.4 1 0 0 1 1 1 0 Importin repeat 6 RXT2_N PF08595.11 EGO59798.1 - 0.37 10.8 2.8 0.79 9.7 2.8 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.6 EGO59798.1 - 2.7 8.4 7.1 8.1 6.9 7.1 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0114 PF03350.16 EGO59799.1 - 0.083 13.1 0.0 0.088 13.0 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 F-box PF00646.33 EGO59800.1 - 0.0011 18.8 1.2 0.0054 16.6 0.1 2.8 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EGO59800.1 - 0.0079 16.1 1.1 0.035 14.0 0.1 2.6 3 0 0 3 3 3 1 F-box-like LRR_8 PF13855.6 EGO59800.1 - 0.01 15.6 2.1 5.9 6.7 0.0 4.9 6 0 0 6 6 6 0 Leucine rich repeat LRR_4 PF12799.7 EGO59800.1 - 0.016 15.6 4.6 26 5.4 0.3 4.8 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) F-box_4 PF15966.5 EGO59800.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 F-box F-box-like_2 PF13013.6 EGO59800.1 - 0.073 13.0 0.3 0.23 11.4 0.0 2.0 2 1 0 2 2 2 0 F-box-like domain IBR PF01485.21 EGO59801.1 - 5.9e-06 26.4 4.7 5.9e-06 26.4 4.7 5.0 5 1 0 5 5 5 4 IBR domain, a half RING-finger domain Actin PF00022.19 EGO59802.1 - 2.7e-14 52.6 0.0 4.4e-12 45.3 0.0 2.6 3 0 0 3 3 3 2 Actin SAP PF02037.27 EGO59803.1 - 1.1e-07 31.4 0.1 2.7e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 SAP domain SprA-related PF12118.8 EGO59803.1 - 0.0035 16.5 4.0 0.0035 16.5 4.0 2.1 1 1 0 2 2 2 1 SprA-related family EMP24_GP25L PF01105.24 EGO59803.1 - 0.022 14.7 0.6 0.022 14.7 0.6 2.2 2 0 0 2 2 1 0 emp24/gp25L/p24 family/GOLD SUFU_C PF12470.8 EGO59803.1 - 1.3 9.0 8.3 0.2 11.7 3.0 2.0 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain VIR_N PF15912.5 EGO59803.1 - 1.3 8.6 13.9 1 8.9 6.2 2.2 2 0 0 2 2 2 0 Virilizer, N-terminal Zf_RING PF16744.5 EGO59803.1 - 1.9 8.7 5.1 4.8 7.4 5.1 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger MMR1 PF08505.10 EGO59803.1 - 2.4 8.4 17.1 0.58 10.4 10.7 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein SID-1_RNA_chan PF13965.6 EGO59803.1 - 2.4 6.4 4.4 0.22 9.9 0.1 1.4 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 PHD PF00628.29 EGO59803.1 - 3.5 7.6 8.4 7.1 6.6 8.4 1.6 1 0 0 1 1 1 0 PHD-finger CPSF100_C PF13299.6 EGO59803.1 - 5.3 7.2 13.1 0.21 11.7 6.0 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIP PF07454.11 EGO59803.1 - 5.3 6.4 13.5 0.15 11.5 6.9 1.7 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Hid1 PF12722.7 EGO59803.1 - 5.9 4.9 8.5 9.2 4.3 8.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CSG2 PF16965.5 EGO59803.1 - 6.4 5.6 4.6 12 4.7 4.6 1.4 1 0 0 1 1 1 0 Ceramide synthase regulator BIRC6 PF12356.8 EGO59803.1 - 6.5 6.1 7.0 1.1 8.7 2.6 1.9 2 0 0 2 2 2 0 Baculoviral IAP repeat-containing protein 6 PHD PF00628.29 EGO59804.1 - 0.02 14.8 3.8 0.035 14.0 3.8 1.4 1 0 0 1 1 1 0 PHD-finger DUF3305 PF11749.8 EGO59804.1 - 0.059 13.5 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3305) zf-H2C2_5 PF13909.6 EGO59804.1 - 0.1 12.4 0.2 0.21 11.4 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Dodecin PF07311.12 EGO59804.1 - 0.18 12.0 0.1 0.4 11.0 0.1 1.5 1 0 0 1 1 1 0 Dodecin PHD PF00628.29 EGO59806.1 - 0.0028 17.5 6.2 0.0056 16.5 6.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_3 PF13920.6 EGO59806.1 - 0.02 14.8 8.6 0.12 12.3 8.6 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 EGO59806.1 - 0.022 14.6 3.8 0.022 14.6 3.8 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.6 EGO59806.1 - 0.028 14.2 5.1 0.028 14.2 5.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO59806.1 - 0.07 13.5 6.4 0.16 12.3 6.4 1.7 1 0 0 1 1 1 0 Ring finger domain SesA PF17107.5 EGO59806.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases zf-RING_9 PF13901.6 EGO59806.1 - 0.21 11.5 5.8 0.14 12.1 3.8 1.8 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Prok-RING_1 PF14446.6 EGO59806.1 - 0.35 10.8 7.7 0.069 13.1 3.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 EGO59806.1 - 1 9.4 7.4 2.1 8.4 7.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DUF2076 PF09849.9 EGO59806.1 - 1.9 8.5 5.3 0.26 11.3 0.6 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) C1_2 PF03107.16 EGO59807.1 - 0.013 15.8 4.0 0.031 14.6 4.0 1.7 1 0 0 1 1 1 0 C1 domain FYVE PF01363.21 EGO59807.1 - 0.042 14.0 6.7 0.12 12.6 6.7 1.9 1 1 0 1 1 1 0 FYVE zinc finger FemAB PF02388.16 EGO59807.1 - 0.21 10.4 6.0 0.37 9.6 6.0 1.3 1 0 0 1 1 1 0 FemAB family zf-RING_2 PF13639.6 EGO59807.1 - 0.4 11.1 7.1 0.87 10.0 7.1 1.6 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 EGO59807.1 - 1.3 9.0 8.3 3.5 7.6 8.3 1.7 1 0 0 1 1 1 0 PHD-finger PHM7_cyt PF14703.6 EGO59807.1 - 2.6 8.2 8.4 6 7.1 7.4 2.1 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Syntaxin-6_N PF09177.11 EGO59807.1 - 4.5 7.9 10.1 1.9 9.1 1.0 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal PHD PF00628.29 EGO59808.1 - 0.0033 17.3 10.0 0.0061 16.4 10.0 1.4 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 EGO59808.1 - 0.46 10.8 9.2 0.83 10.0 9.2 1.4 1 0 0 1 1 1 0 Ring finger domain Ax_dynein_light PF10211.9 EGO59808.1 - 0.61 10.0 12.5 1.1 9.2 12.5 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain DUF3450 PF11932.8 EGO59808.1 - 0.63 9.3 5.2 0.97 8.7 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) C1_1 PF00130.22 EGO59808.1 - 0.71 9.8 11.0 0.084 12.8 5.4 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Fzo_mitofusin PF04799.13 EGO59808.1 - 0.74 9.4 5.3 1.3 8.5 5.3 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF4337 PF14235.6 EGO59808.1 - 1.1 9.3 7.9 2.2 8.4 7.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) OmpH PF03938.14 EGO59808.1 - 1.2 9.5 8.7 2 8.7 8.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3810 PF12725.7 EGO59808.1 - 1.2 8.4 5.4 1.7 7.9 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) KIX PF02172.16 EGO59810.1 - 0.012 15.8 1.0 0.026 14.8 1.0 1.5 1 0 0 1 1 1 0 KIX domain DUF1177 PF06675.11 EGO59810.1 - 0.047 12.5 0.1 0.075 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) APG6_N PF17675.1 EGO59810.1 - 0.054 14.0 1.3 0.097 13.2 1.3 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region FlxA PF14282.6 EGO59810.1 - 0.07 13.1 1.3 0.18 11.8 1.3 1.7 1 0 0 1 1 1 0 FlxA-like protein DUF2721 PF11026.8 EGO59810.1 - 0.13 12.2 3.2 0.22 11.4 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF724 PF05266.14 EGO59810.1 - 0.27 11.0 4.0 0.45 10.3 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) CRT-like PF08627.10 EGO59811.1 - 0.21 10.5 0.0 1.3 7.9 0.1 1.8 1 1 1 2 2 2 0 CRT-like, chloroquine-resistance transporter-like adh_short PF00106.25 EGO59815.1 - 6.5e-83 277.0 9.4 6.9e-44 149.7 1.0 2.8 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO59815.1 - 6e-62 209.2 8.8 1.5e-33 116.3 1.5 2.9 2 2 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EGO59815.1 - 1.6e-36 124.6 0.0 3.1e-36 123.6 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EGO59815.1 - 6.1e-28 97.9 2.5 1.8e-13 50.8 0.2 2.4 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 EGO59815.1 - 0.00074 18.9 0.9 0.0069 15.7 0.3 2.3 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MaoC_dehydrat_N PF13452.6 EGO59815.1 - 0.0013 18.9 0.0 2.3 8.4 0.0 2.8 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase PglL_A PF15864.5 EGO59815.1 - 4.5 7.1 8.1 10 6.0 1.0 2.4 2 0 0 2 2 2 0 Protein glycosylation ligase SRP54 PF00448.22 EGO59816.1 - 3.8e-07 29.9 0.0 5.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 EGO59816.1 - 6.4e-05 23.5 0.1 0.00017 22.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EGO59816.1 - 0.00063 18.8 0.0 0.00096 18.2 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KAP_NTPase PF07693.14 EGO59816.1 - 0.00064 19.1 0.0 0.00096 18.5 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain cobW PF02492.19 EGO59816.1 - 0.0019 17.8 0.1 0.0029 17.2 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EGO59816.1 - 0.0023 18.3 0.0 0.0054 17.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGO59816.1 - 0.0024 17.9 0.0 0.0045 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGO59816.1 - 0.0025 17.1 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 EGO59816.1 - 0.0025 18.2 0.0 0.0045 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EGO59816.1 - 0.0027 17.6 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TsaE PF02367.17 EGO59816.1 - 0.0084 16.1 0.0 0.031 14.3 0.0 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EGO59816.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 EGO59816.1 - 0.012 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGO59816.1 - 0.013 16.0 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.17 EGO59816.1 - 0.013 15.1 0.4 0.12 12.0 0.1 2.4 3 0 0 3 3 3 0 Thymidylate kinase NTPase_1 PF03266.15 EGO59816.1 - 0.015 15.3 0.2 0.023 14.6 0.2 1.3 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 EGO59816.1 - 0.016 15.3 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 EGO59816.1 - 0.017 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EGO59816.1 - 0.033 14.2 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 EGO59816.1 - 0.039 13.7 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PRK PF00485.18 EGO59816.1 - 0.042 13.6 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.6 EGO59816.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGO59816.1 - 0.062 13.5 0.1 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EGO59816.1 - 0.063 13.2 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArsA_ATPase PF02374.15 EGO59816.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase ATPase_2 PF01637.18 EGO59816.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EGO59816.1 - 0.084 13.3 0.0 0.21 12.0 0.0 1.8 1 1 0 1 1 1 0 RNA helicase LpxK PF02606.14 EGO59816.1 - 0.085 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase AAA_5 PF07728.14 EGO59816.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CBP_BcsQ PF06564.12 EGO59816.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ dNK PF01712.19 EGO59816.1 - 0.17 11.7 0.1 0.69 9.7 0.0 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase KTI12 PF08433.10 EGO59816.1 - 0.19 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ECM11 PF15463.6 EGO59817.1 - 2.5e-42 144.6 8.2 2.5e-42 144.6 8.2 2.4 2 0 0 2 2 2 1 Extracellular mutant protein 11 ParA PF10609.9 EGO59818.1 - 1.2e-94 316.4 0.0 1.4e-94 316.1 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGO59818.1 - 2.3e-07 30.9 0.0 4.6e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EGO59818.1 - 2.4e-05 23.7 0.3 0.0005 19.3 0.1 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 EGO59818.1 - 6.2e-05 23.0 0.1 0.00063 19.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGO59818.1 - 0.0015 18.1 0.1 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGO59818.1 - 0.011 15.6 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 EGO59818.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_30 PF13604.6 EGO59818.1 - 0.024 14.3 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain MipZ PF09140.11 EGO59818.1 - 0.034 13.4 0.0 0.077 12.3 0.0 1.6 1 1 0 1 1 1 0 ATPase MipZ CLP1_P PF16575.5 EGO59818.1 - 0.036 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 EGO59818.1 - 0.039 13.6 0.0 0.07 12.7 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_26 PF13500.6 EGO59818.1 - 0.044 13.6 0.1 5.5 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain CBP_BcsQ PF06564.12 EGO59818.1 - 0.055 12.9 0.1 0.31 10.5 0.1 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ RNA_helicase PF00910.22 EGO59818.1 - 0.072 13.5 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Fer4_NifH PF00142.18 EGO59818.1 - 0.078 12.4 0.0 0.63 9.4 0.1 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_5 PF07728.14 EGO59818.1 - 0.078 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO59818.1 - 0.092 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 EGO59818.1 - 0.14 11.1 0.2 0.21 10.6 0.2 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EGO59818.1 - 0.17 12.0 0.1 9.6 6.3 0.1 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase TsaE PF02367.17 EGO59818.1 - 0.18 11.8 0.1 0.35 10.9 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ras PF00071.22 EGO59818.1 - 0.19 11.3 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 Ras family NB-ARC PF00931.22 EGO59818.1 - 0.25 10.5 0.1 0.4 9.8 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain MoCF_biosynth PF00994.24 EGO59819.1 - 6.3e-29 100.5 0.0 1.1e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.22 EGO59820.1 - 2.6e-58 196.2 0.1 3.2e-58 195.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO59820.1 - 3.6e-20 72.4 0.0 9.8e-20 71.0 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO59820.1 - 2.6e-09 36.8 0.0 3.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGO59820.1 - 4.1e-06 26.5 0.1 1.7e-05 24.4 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGO59820.1 - 0.00052 20.0 0.7 0.74 9.7 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGO59820.1 - 0.0006 19.9 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF3783 PF12646.7 EGO59820.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) Kelch_5 PF13854.6 EGO59822.1 - 5e-15 55.1 3.1 1.2e-11 44.3 0.2 3.8 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 EGO59822.1 - 3.6e-05 23.3 2.2 2 8.0 0.0 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 EGO59822.1 - 0.00068 19.6 1.4 2.2 8.4 0.1 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EGO59822.1 - 0.0023 18.2 3.2 0.0075 16.5 0.2 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EGO59822.1 - 0.005 17.1 4.6 0.076 13.3 0.5 4.0 2 1 1 3 3 3 1 Kelch motif DUF4381 PF14316.6 EGO59822.1 - 0.015 15.5 0.4 0.029 14.6 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Cys_rich_CPXG PF14255.6 EGO59823.1 - 1.1 9.2 4.9 0.77 9.7 0.3 2.5 2 0 0 2 2 2 0 Cysteine-rich CPXCG DUF3632 PF12311.8 EGO59826.1 - 1.6e-06 28.6 4.7 3e-06 27.8 4.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) ArfGap PF01412.18 EGO59828.1 - 2.2e-35 121.2 0.9 4.2e-35 120.3 0.2 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf TIM21 PF08294.11 EGO59829.1 - 3.9e-52 176.0 0.0 5.3e-52 175.6 0.0 1.2 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 EGO59829.1 - 3e-05 23.7 0.0 0.00015 21.4 0.0 2.1 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 FAD-oxidase_C PF02913.19 EGO59829.1 - 0.034 13.8 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain P5-ATPase PF12409.8 EGO59829.1 - 0.22 11.6 1.6 0.38 10.9 0.8 1.7 2 0 0 2 2 2 0 P5-type ATPase cation transporter Bromodomain PF00439.25 EGO59831.1 - 1.9e-16 59.9 0.8 3e-16 59.2 0.1 1.7 2 0 0 2 2 2 1 Bromodomain BTB PF00651.31 EGO59831.1 - 3.1e-05 24.1 0.0 6.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain ATPase PF06745.13 EGO59832.1 - 1e-05 25.0 0.0 1.3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 EGO59832.1 - 0.00022 20.9 0.2 0.00049 19.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 EGO59832.1 - 0.00036 20.1 0.0 0.00049 19.6 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 EGO59832.1 - 0.00074 18.8 0.1 0.0011 18.3 0.1 1.1 1 0 0 1 1 1 1 Rad51 DnaB_C PF03796.15 EGO59832.1 - 0.001 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 EGO59832.1 - 0.022 14.5 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 EGO59832.1 - 0.12 12.2 0.4 0.21 11.3 0.0 1.6 1 1 1 2 2 2 0 AAA domain zf-H2C2_2 PF13465.6 EGO59834.1 - 7.3e-07 29.3 25.8 2.1e-05 24.7 3.5 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 EGO59834.1 - 1.9e-06 28.0 20.0 0.00047 20.5 4.5 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO59834.1 - 0.0017 19.0 15.3 0.054 14.4 3.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EGO59834.1 - 0.017 15.4 1.6 0.11 12.8 0.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 EGO59834.1 - 0.022 15.0 3.0 0.056 13.8 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EGO59834.1 - 0.047 13.7 2.3 2.5 8.2 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 EGO59834.1 - 0.067 13.8 0.6 0.067 13.8 0.6 2.5 2 1 1 3 3 3 0 FOXP coiled-coil domain DUF2225 PF09986.9 EGO59834.1 - 0.42 10.3 0.7 1.1 9.0 0.6 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-H2C2_5 PF13909.6 EGO59834.1 - 1.7 8.5 11.9 3.2 7.6 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain FPN1 PF06963.12 EGO59836.1 - 6.1e-115 384.2 10.6 7.2e-115 384.0 10.6 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Amidase PF01425.21 EGO59837.1 - 4.8e-94 315.9 0.0 1.6e-93 314.2 0.0 1.7 1 1 0 1 1 1 1 Amidase Glyco_hydro_76 PF03663.14 EGO59842.1 - 2.2e-133 445.3 9.9 2.5e-133 445.1 9.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MscL PF01741.18 EGO59845.1 - 2.2e-17 63.5 0.2 2.7e-17 63.2 0.2 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL NMO PF03060.15 EGO59847.1 - 6.6e-55 186.8 0.3 9.4e-55 186.3 0.3 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGO59847.1 - 7.5e-13 48.2 1.1 1.2e-12 47.6 1.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGO59847.1 - 8e-07 28.4 2.2 1.2e-06 27.8 2.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EGO59847.1 - 0.0014 17.9 1.2 0.0023 17.1 1.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 EGO59847.1 - 0.0033 16.7 0.3 0.006 15.8 0.3 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NanE PF04131.14 EGO59847.1 - 0.012 14.8 0.4 0.032 13.4 0.1 1.9 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Pterin_bind PF00809.22 EGO59848.1 - 5.2e-74 249.0 0.0 6.8e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EGO59848.1 - 2.8e-35 121.2 0.0 4.7e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Oxidored_nitro PF00148.19 EGO59848.1 - 0.11 11.2 0.0 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase DUF4850 PF16142.5 EGO59850.1 - 0.00039 20.0 0.1 0.00075 19.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4850) BNR_2 PF13088.6 EGO59852.1 - 0.00028 20.3 0.0 0.00046 19.6 0.0 1.4 1 0 0 1 1 1 1 BNR repeat-like domain Sortilin-Vps10 PF15902.5 EGO59852.1 - 0.17 10.6 0.1 5.3 5.7 0.0 2.1 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, Glyco_hydro_3_C PF01915.22 EGO59853.1 - 5.9e-39 134.1 0.1 9.5e-39 133.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO59853.1 - 1.2e-33 116.8 0.0 1.9e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGO59853.1 - 4.9e-07 29.8 0.0 9.9e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain LRR_1 PF00560.33 EGO59854.1 - 0.03 14.8 4.0 90 4.2 0.1 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 EGO59854.1 - 7.3 7.2 8.2 23 5.6 0.3 4.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Maf_N PF08383.11 EGO59858.1 - 0.064 13.0 0.5 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 Maf N-terminal region NDT80_PhoG PF05224.12 EGO59859.1 - 1.7e-54 184.9 0.3 7.1e-54 182.9 0.1 1.9 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family CAP_N PF01213.19 EGO59862.1 - 0.22 11.0 4.6 0.29 10.6 4.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EGO59862.1 - 1 9.4 6.7 1.5 8.9 6.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator LysM PF01476.20 EGO59863.1 - 9.3e-35 118.4 8.9 5.7e-08 32.7 0.0 5.2 5 0 0 5 5 5 5 LysM domain UPF0203 PF05254.12 EGO59863.1 - 6.7e-05 23.1 7.0 3.2 8.1 0.2 4.5 4 0 0 4 4 4 3 Uncharacterised protein family (UPF0203) HTH_23 PF13384.6 EGO59863.1 - 0.02 14.7 0.0 25 4.8 0.0 3.7 4 0 0 4 4 4 0 Homeodomain-like domain FhuF_C PF11575.8 EGO59863.1 - 0.02 14.8 2.2 35 4.5 0.1 4.6 4 0 0 4 4 4 0 FhuF 2Fe-2S C-terminal domain HTH_Tnp_1 PF01527.20 EGO59863.1 - 0.075 13.3 0.0 27 5.1 0.0 3.2 4 0 0 4 4 4 0 Transposase Apt1 PF10351.9 EGO59863.1 - 0.99 8.2 3.0 1.4 7.7 3.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain MAP65_ASE1 PF03999.12 EGO59863.1 - 6.2 5.4 6.8 9.5 4.8 6.8 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Glyco_hydro_18 PF00704.28 EGO59865.1 - 1.6e-43 149.7 0.6 3.8e-43 148.4 0.6 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.6 EGO59865.1 - 1.2e-29 102.6 3.7 1.6e-29 102.2 1.5 2.5 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor Chitin_bind_1 PF00187.19 EGO59865.1 - 0.00033 21.1 10.3 0.00033 21.1 10.3 3.4 3 1 0 3 3 3 1 Chitin recognition protein LysM PF01476.20 EGO59865.1 - 0.0029 17.6 0.0 1.8 8.7 0.0 3.1 2 0 0 2 2 2 2 LysM domain Ank_2 PF12796.7 EGO59866.1 - 2.3e-22 79.4 0.1 1.5e-05 25.5 0.0 5.5 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO59866.1 - 8e-18 64.6 0.5 9.6e-07 29.2 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO59866.1 - 4.1e-15 54.4 0.2 0.091 13.4 0.0 7.8 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 EGO59866.1 - 2.9e-14 52.9 0.0 0.0089 16.3 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EGO59866.1 - 8.4e-11 41.8 1.0 0.13 12.8 0.0 7.5 6 2 0 6 6 6 3 Ankyrin repeat NACHT PF05729.12 EGO59866.1 - 0.002 18.1 0.0 0.0048 16.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF2989 PF11207.8 EGO59866.1 - 0.036 13.8 0.7 2 8.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) UBN_AB PF14075.6 EGO59866.1 - 0.11 12.2 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Ubinuclein conserved middle domain PNP_UDP_1 PF01048.20 EGO59867.1 - 1.8e-10 40.5 0.1 2.4e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Ran_BP1 PF00638.18 EGO59868.1 - 7.8e-11 42.3 0.3 3.1e-05 24.2 0.1 2.4 2 0 0 2 2 2 2 RanBP1 domain YL1 PF05764.13 EGO59869.1 - 0.0091 16.1 20.3 0.044 13.9 0.5 3.2 3 0 0 3 3 3 3 YL1 nuclear protein Connexin PF00029.19 EGO59869.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Connexin zf-RING_2 PF13639.6 EGO59870.1 - 2.7e-14 53.2 6.8 2.7e-14 53.2 6.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EGO59870.1 - 1.5e-10 40.6 2.3 1.5e-10 40.6 2.3 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGO59870.1 - 1.3e-09 37.7 6.7 1.3e-09 37.7 6.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO59870.1 - 6.1e-09 35.6 7.7 4.2e-08 32.9 2.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGO59870.1 - 2.4e-07 30.9 5.9 2.4e-07 30.9 5.9 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGO59870.1 - 1.4e-05 24.9 4.0 1.4e-05 24.9 4.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO59870.1 - 1.4e-05 24.8 6.4 1.4e-05 24.8 6.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO59870.1 - 3.7e-05 23.5 3.9 3.7e-05 23.5 3.9 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGO59870.1 - 0.00033 20.6 1.2 0.00033 20.6 1.2 2.3 2 1 1 3 3 2 1 RING-type zinc-finger zf-P11 PF03854.14 EGO59870.1 - 0.004 16.8 1.6 0.0095 15.6 1.6 1.7 1 0 0 1 1 1 1 P-11 zinc finger zf-ANAPC11 PF12861.7 EGO59870.1 - 0.004 17.2 1.8 0.011 15.8 1.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.19 EGO59870.1 - 0.058 13.4 0.1 0.058 13.4 0.1 1.8 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1572 PF07609.11 EGO59870.1 - 0.066 13.0 0.8 0.13 12.1 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) zinc_ribbon_9 PF14369.6 EGO59870.1 - 0.11 12.8 8.9 0.11 12.8 5.3 2.4 2 0 0 2 2 2 0 zinc-ribbon RINGv PF12906.7 EGO59870.1 - 0.41 10.8 7.7 0.98 9.6 7.7 1.7 1 0 0 1 1 1 0 RING-variant domain Spt20 PF12090.8 EGO59870.1 - 0.62 9.6 10.8 0.42 10.2 6.5 2.2 2 0 0 2 2 2 0 Spt20 family YdjO PF14169.6 EGO59870.1 - 0.73 9.6 9.3 8 6.3 0.3 4.1 3 1 1 4 4 4 0 Cold-inducible protein YdjO PHD PF00628.29 EGO59870.1 - 2 8.3 13.1 0.27 11.1 5.2 2.6 2 1 1 3 3 3 0 PHD-finger zf-RING_4 PF14570.6 EGO59870.1 - 8.6 6.2 13.8 0.99 9.3 4.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Fis1_TPR_C PF14853.6 EGO59871.1 - 2.6e-26 91.4 2.1 3.7e-26 91.0 2.1 1.2 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EGO59871.1 - 2.2e-17 62.4 0.0 3.8e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EGO59871.1 - 0.0039 17.2 3.8 0.0092 16.0 3.8 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGO59871.1 - 0.026 15.2 0.7 0.054 14.2 0.7 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.11 EGO59872.1 - 9.8e-38 128.6 2.0 2.3e-35 121.0 0.0 2.2 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Myosin_tail_1 PF01576.19 EGO59872.1 - 0.001 17.0 5.8 0.0013 16.7 5.8 1.1 1 0 0 1 1 1 1 Myosin tail DUF5082 PF16888.5 EGO59872.1 - 0.004 17.4 3.3 0.0067 16.7 3.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) FPP PF05911.11 EGO59872.1 - 0.0047 15.2 6.7 0.0058 14.9 6.7 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Prefoldin_2 PF01920.20 EGO59872.1 - 0.0059 16.5 9.8 0.044 13.7 2.4 2.2 2 0 0 2 2 2 2 Prefoldin subunit APG6_N PF17675.1 EGO59872.1 - 0.0073 16.8 12.0 0.012 16.1 12.0 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region HR1 PF02185.16 EGO59872.1 - 0.02 15.0 9.7 0.037 14.2 1.0 2.4 2 0 0 2 2 2 0 Hr1 repeat PLAC9 PF15205.6 EGO59872.1 - 0.026 14.9 0.2 0.051 14.0 0.2 1.5 1 0 0 1 1 1 0 Placenta-specific protein 9 FlaC_arch PF05377.11 EGO59872.1 - 0.032 14.6 5.9 1.9 9.0 0.4 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) WDCP PF15390.6 EGO59872.1 - 0.043 12.2 4.7 0.055 11.9 4.7 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF3073 PF11273.8 EGO59872.1 - 0.044 14.5 1.2 0.044 14.5 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3073) MAP65_ASE1 PF03999.12 EGO59872.1 - 0.049 12.3 7.3 0.062 12.0 7.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF2353 PF09789.9 EGO59872.1 - 0.059 12.7 6.9 0.082 12.3 6.9 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) FliJ PF02050.16 EGO59872.1 - 0.067 13.4 9.9 0.11 12.7 9.9 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein Exonuc_VII_L PF02601.15 EGO59872.1 - 0.094 12.3 4.9 0.12 11.9 4.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2802 PF10975.8 EGO59872.1 - 0.16 12.1 4.6 8.5 6.6 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2802) CLZ PF16526.5 EGO59872.1 - 0.2 12.1 11.5 1.2 9.5 2.9 2.6 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BSP_II PF05432.11 EGO59872.1 - 0.22 11.2 2.1 0.28 10.9 2.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Trimer_CC PF08954.11 EGO59872.1 - 0.22 11.1 14.1 8.5 6.0 9.8 3.1 1 1 2 3 3 3 0 Trimerisation motif DUF4407 PF14362.6 EGO59872.1 - 0.26 10.6 7.0 0.91 8.8 6.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 EGO59872.1 - 0.35 9.4 3.5 0.4 9.2 3.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1690 PF07956.11 EGO59872.1 - 0.53 10.7 10.6 1.4 9.3 8.6 2.0 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) XhlA PF10779.9 EGO59872.1 - 0.54 10.5 4.7 5.6 7.2 0.4 2.2 2 0 0 2 2 2 0 Haemolysin XhlA DUF3573 PF12097.8 EGO59872.1 - 0.81 8.5 2.7 0.71 8.6 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) FAM76 PF16046.5 EGO59872.1 - 1 8.7 4.5 1.3 8.3 4.5 1.1 1 0 0 1 1 1 0 FAM76 protein Swi5 PF07061.11 EGO59872.1 - 1 9.5 4.7 4.8 7.4 0.2 2.4 2 0 0 2 2 2 0 Swi5 Allexi_40kDa PF05549.11 EGO59872.1 - 1.2 8.6 6.7 4.7 6.6 6.7 1.8 1 1 0 1 1 1 0 Allexivirus 40kDa protein ZapA PF05164.13 EGO59872.1 - 1.4 9.4 6.8 2.6 8.6 6.7 1.5 1 1 0 1 1 1 0 Cell division protein ZapA SlyX PF04102.12 EGO59872.1 - 1.5 9.5 10.1 1.1 9.9 2.5 2.7 1 1 1 2 2 2 0 SlyX GAS PF13851.6 EGO59872.1 - 1.8 7.9 11.5 1.1 8.6 2.3 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 EGO59872.1 - 2 8.6 5.9 3.3 7.9 5.9 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Rx_N PF18052.1 EGO59872.1 - 2.1 8.7 7.7 5.5 7.3 0.7 2.3 1 1 1 2 2 2 0 Rx N-terminal domain NPV_P10 PF05531.12 EGO59872.1 - 2.3 8.8 6.7 12 6.4 0.8 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4164 PF13747.6 EGO59872.1 - 2.7 8.3 11.9 62 4.0 11.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Uso1_p115_C PF04871.13 EGO59872.1 - 3.7 7.9 10.8 9.5 6.6 1.2 1.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Noelin-1 PF12308.8 EGO59872.1 - 3.8 7.5 7.0 1.3 9.1 1.8 2.2 1 1 1 2 2 2 0 Neurogenesis glycoprotein TMF_DNA_bd PF12329.8 EGO59872.1 - 5.5 7.1 11.5 2.4 8.2 3.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.17 EGO59872.1 - 8.2 6.4 9.6 11 5.9 1.8 2.3 1 1 0 2 2 2 0 Prefoldin subunit DUF4140 PF13600.6 EGO59872.1 - 9.4 6.7 10.7 1.8e+03 -0.6 10.7 2.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TatD_DNase PF01026.21 EGO59875.1 - 5.8e-31 107.8 0.0 1.5e-30 106.4 0.0 1.7 1 1 0 1 1 1 1 TatD related DNase Fungal_trans PF04082.18 EGO59876.1 - 3.5e-22 78.7 0.3 5.8e-22 78.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SelP_N PF04592.14 EGO59876.1 - 0.24 10.8 14.6 0.45 9.9 14.6 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pyridox_oxase_2 PF12766.7 EGO59879.1 - 3.8e-15 56.3 0.0 4.8e-14 52.8 0.0 2.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RNA_pol_Rpb5_C PF01191.19 EGO59880.1 - 1.3e-33 114.7 1.0 2.8e-33 113.6 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EGO59880.1 - 2e-28 98.8 0.0 3.2e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EGO59880.1 - 0.002 18.2 0.0 0.0052 16.8 0.0 1.7 2 0 0 2 2 2 1 Restriction endonuclease EzrA PF06160.12 EGO59881.1 - 2.5e-07 29.3 19.8 2.5e-07 29.3 19.8 3.1 2 1 1 3 3 3 1 Septation ring formation regulator, EzrA ABC_tran_CTD PF16326.5 EGO59881.1 - 5.1e-05 23.4 7.8 5.1e-05 23.4 7.8 7.1 3 3 5 8 8 8 1 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 EGO59881.1 - 1.3 9.0 10.2 5.4 7.1 0.9 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EGO59881.1 - 2 8.6 33.6 0.22 11.7 6.0 4.2 2 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 EGO59881.1 - 2.9 7.2 54.3 0.48 9.7 22.8 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) PSI_PsaF PF02507.15 EGO59881.1 - 3.5 7.5 11.3 0.99 9.2 0.5 3.4 3 1 0 3 3 3 0 Photosystem I reaction centre subunit III DUF4239 PF14023.6 EGO59881.1 - 7.2 6.3 14.0 0.25 11.0 1.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4239) GTP1_OBG PF01018.22 EGO59883.1 - 1.7e-41 141.4 1.1 9.3e-30 103.3 4.7 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 EGO59883.1 - 1.1e-24 86.8 0.0 1.8e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO59883.1 - 8.4e-07 28.6 0.1 2.4e-06 27.2 0.1 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.27 EGO59883.1 - 0.04 14.4 0.0 0.077 13.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 EGO59883.1 - 0.05 12.6 0.0 0.16 10.9 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 EGO59883.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_18 PF13238.6 EGO59883.1 - 0.16 12.5 0.0 0.48 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Methyltr_RsmB-F PF01189.17 EGO59884.1 - 5.7e-32 111.0 0.0 1.4e-24 86.9 0.0 3.0 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EGO59884.1 - 0.062 13.4 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase WD40 PF00400.32 EGO59885.1 - 6.5e-13 49.0 15.7 1.1e-05 26.1 0.2 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO59885.1 - 0.00057 20.1 0.1 0.08 13.2 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_I_TF PF04090.12 EGO59886.1 - 2.6e-06 27.1 0.0 0.00069 19.2 0.0 2.5 2 1 0 2 2 2 2 RNA polymerase I specific initiation factor MRP-S33 PF08293.11 EGO59886.1 - 0.011 15.9 2.1 2.8 8.2 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit S27 DUF1952 PF09189.10 EGO59886.1 - 0.036 13.9 0.1 0.091 12.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) ETC_C1_NDUFA5 PF04716.14 EGO59887.1 - 4.6e-27 93.6 0.5 7.2e-25 86.6 0.2 2.5 2 0 0 2 2 2 2 ETC complex I subunit conserved region Mo-co_dimer PF03404.16 EGO59888.1 - 5.5e-61 204.6 0.0 1.1e-60 203.6 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 EGO59888.1 - 1.1e-54 184.6 0.1 2.4e-54 183.5 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 EGO59888.1 - 3.1e-32 110.9 0.0 5.5e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGO59888.1 - 2.6e-28 98.8 0.0 5.4e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 EGO59888.1 - 5.8e-22 77.6 0.0 1.1e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EGO59888.1 - 0.0011 19.1 0.8 0.098 12.8 0.0 2.8 3 0 0 3 3 3 1 Ferric reductase NAD binding domain GCP_N_terminal PF17681.1 EGO59889.1 - 1.2e-65 222.2 0.4 3.4e-65 220.7 0.0 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGO59889.1 - 3.8e-58 197.4 5.1 3.8e-58 197.4 5.1 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal SUIM_assoc PF16619.5 EGO59889.1 - 0.014 15.4 13.7 0.036 14.1 5.6 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 EGO59889.1 - 0.47 10.0 11.3 0.38 10.3 4.7 2.3 2 0 0 2 2 2 0 Spt20 family PRIMA1 PF16101.5 EGO59889.1 - 1.2 9.2 9.2 2.7 8.1 9.2 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 M_domain PF12938.7 EGO59889.1 - 1.6 8.5 16.4 0.4 10.4 8.9 2.4 2 0 0 2 2 2 0 M domain of GW182 Proteasome PF00227.26 EGO59890.1 - 5.9e-57 192.2 0.2 7.4e-57 191.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGO59890.1 - 1.7e-12 46.8 0.0 3.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Fungal_trans_2 PF11951.8 EGO59891.1 - 5.4e-18 65.0 0.7 5.1e-17 61.8 0.7 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO59891.1 - 8.1e-08 32.3 11.2 1.4e-07 31.5 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGO59891.1 - 0.0052 15.8 1.3 0.0093 15.0 1.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_8 PF05148.15 EGO59892.1 - 1.2e-54 185.5 0.0 7.1e-52 176.4 0.0 2.6 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EGO59892.1 - 5.5e-09 36.6 0.0 3.2e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO59892.1 - 6.4e-06 26.8 0.1 9.6e-05 23.0 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO59892.1 - 0.0016 18.3 0.0 0.51 10.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Ribosomal_60s PF00428.19 EGO59892.1 - 0.019 15.6 1.6 0.019 15.6 1.6 5.4 2 1 3 5 5 3 0 60s Acidic ribosomal protein Methyltransf_32 PF13679.6 EGO59892.1 - 0.22 11.5 9.5 0.29 11.1 0.0 3.2 3 0 0 3 3 3 0 Methyltransferase domain DUF966 PF06136.13 EGO59892.1 - 0.71 9.5 13.7 1.4 8.6 13.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Dicty_REP PF05086.12 EGO59892.1 - 1.1 7.1 11.8 1.5 6.7 11.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Zip PF02535.22 EGO59892.1 - 2.7 7.1 3.9 24 4.0 5.0 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter XRN_M PF17846.1 EGO59892.1 - 3.7 6.4 10.1 7.4 5.4 10.1 1.4 1 0 0 1 1 1 0 Xrn1 helical domain TMEM214 PF10151.9 EGO59892.1 - 6.1 5.2 14.7 9.2 4.6 14.7 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF4551 PF15087.6 EGO59892.1 - 7.9 5.2 10.8 12 4.6 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF2201_N PF13203.6 EGO59892.1 - 9.3 5.8 13.7 4.3 6.8 8.5 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain Pribosyltran PF00156.27 EGO59894.1 - 5.4e-14 52.0 0.5 7.9e-14 51.5 0.5 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NOG1_N PF17835.1 EGO59895.1 - 8.4e-44 149.4 0.3 8.4e-44 149.4 0.3 2.0 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EGO59895.1 - 1.3e-28 98.8 1.6 3.4e-28 97.4 1.6 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 EGO59895.1 - 4.3e-26 90.5 0.1 8.7e-26 89.5 0.1 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EGO59895.1 - 1.3e-14 54.3 0.0 2.8e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO59895.1 - 3.6e-09 36.3 0.0 6.6e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EGO59895.1 - 0.048 14.1 0.0 0.22 11.9 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EGO59895.1 - 0.076 12.9 0.4 4.6 7.1 0.1 3.1 2 1 0 2 2 2 0 RsgA GTPase Med26 PF08711.11 EGO59895.1 - 0.077 13.0 0.1 0.91 9.6 0.0 2.6 2 0 0 2 2 2 0 TFIIS helical bundle-like domain GDI PF00996.18 EGO59896.1 - 2e-196 652.7 0.0 2.5e-196 652.4 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 EGO59896.1 - 0.0063 16.7 0.0 0.086 13.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.13 EGO59897.1 - 4.3e-23 81.2 1.0 7.3e-23 80.5 1.0 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.12 EGO59897.1 - 0.22 11.0 0.5 0.37 10.2 0.5 1.3 1 0 0 1 1 1 0 Clc-like REV1_C PF16727.5 EGO59898.1 - 0.1 13.0 0.1 0.12 12.8 0.1 1.1 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain zf-H2C2_2 PF13465.6 EGO59899.1 - 4.3e-06 26.9 11.3 7.3e-06 26.2 1.1 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO59899.1 - 0.00022 21.8 14.4 0.025 15.4 5.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 EGO59899.1 - 0.00027 21.2 4.1 0.0005 20.3 4.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 EGO59899.1 - 0.029 14.7 2.4 3.6 8.0 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EGO59899.1 - 0.045 14.2 13.5 0.15 12.6 7.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ndc1_Nup PF09531.10 EGO59899.1 - 0.53 8.9 6.2 0.61 8.7 6.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GCP_C_terminal PF04130.13 EGO59902.1 - 5.4e-67 226.4 0.0 8.2e-67 225.8 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EGO59902.1 - 1.6e-22 80.5 0.4 5.6e-22 78.7 0.0 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Eaf7 PF07904.13 EGO59903.1 - 3.7e-14 53.0 5.8 4.1e-14 52.8 0.0 3.1 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 NOA36 PF06524.12 EGO59903.1 - 1.5 8.1 14.8 2.3 7.5 14.8 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleo_P87 PF07267.11 EGO59903.1 - 1.8 7.3 10.9 2.3 7.0 10.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PPP4R2 PF09184.11 EGO59903.1 - 1.9 8.0 19.0 2.8 7.4 19.0 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 EGO59903.1 - 4.2 5.5 18.6 5.4 5.1 18.6 1.1 1 0 0 1 1 1 0 Nop14-like family Ilar_coat PF01787.16 EGO59903.1 - 5.2 6.8 7.2 0.19 11.5 0.4 2.0 2 1 0 2 2 2 0 Ilarvirus coat protein DUF4746 PF15928.5 EGO59903.1 - 9.2 5.6 16.1 18 4.7 16.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DASH_Ask1 PF08655.10 EGO59904.1 - 1.4e-27 95.3 0.2 2.5e-27 94.5 0.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 Rhodanese PF00581.20 EGO59905.1 - 1.3e-10 41.8 0.0 2.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain p450 PF00067.22 EGO59906.1 - 6.7e-52 176.8 0.0 9.3e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Apt1 PF10351.9 EGO59907.1 - 2.5 6.9 13.1 3.1 6.5 13.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EGO59907.1 - 3.8 6.0 11.0 3.9 5.9 11.0 1.0 1 0 0 1 1 1 0 Macoilin family Yip1 PF04893.17 EGO59908.1 - 1.6e-13 50.8 17.2 3.2e-13 49.8 17.2 1.5 1 1 0 1 1 1 1 Yip1 domain DUF2070 PF09843.9 EGO59908.1 - 0.2 9.9 5.1 0.26 9.5 5.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ubiquitin PF00240.23 EGO59909.1 - 1.4e-34 117.7 0.7 1.5e-34 117.6 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGO59909.1 - 2.2e-15 56.3 0.6 2.4e-15 56.1 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGO59909.1 - 1.8e-06 28.3 0.1 8.2e-06 26.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGO59909.1 - 0.00082 19.3 0.0 0.00091 19.1 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGO59909.1 - 0.00093 19.5 0.1 0.0011 19.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGO59909.1 - 0.0011 19.1 0.1 0.0027 17.8 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGO59909.1 - 0.0041 17.7 0.1 0.0047 17.5 0.1 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EGO59909.1 - 0.0081 16.2 0.2 2.1 8.5 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin-like domain zf-RRN7 PF11781.8 EGO59910.1 - 4e-08 32.8 4.8 7.3e-08 32.0 4.8 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-5a PF01287.20 EGO59911.1 - 1.1e-23 83.1 0.7 1.6e-23 82.6 0.7 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EGO59911.1 - 0.0027 17.7 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.12 EGO59912.1 - 3.9e-127 425.1 0.5 4.6e-127 424.8 0.5 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 EGO59912.1 - 6e-06 25.0 4.0 2e-05 23.2 4.0 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec3 Mer2 PF09074.10 EGO59912.1 - 0.0056 16.5 0.8 0.29 10.9 0.1 3.0 3 0 0 3 3 3 1 Mer2 THOC7 PF05615.13 EGO59912.1 - 0.0091 16.3 0.1 0.13 12.5 0.0 2.4 2 0 0 2 2 2 1 Tho complex subunit 7 Spc7 PF08317.11 EGO59912.1 - 0.018 13.9 0.5 0.033 13.1 0.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 EGO59912.1 - 0.021 14.1 0.5 0.053 12.9 0.5 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 EGO59912.1 - 0.026 14.1 0.5 0.072 12.7 0.5 1.7 1 0 0 1 1 1 0 Intermediate filament protein COG2 PF06148.11 EGO59912.1 - 0.069 13.2 0.3 0.31 11.1 0.2 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 EGO59912.1 - 0.12 12.4 0.9 0.25 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RabGAP-TBC PF00566.18 EGO59913.1 - 1.9e-24 86.5 0.0 2.6e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.9 EGO59914.1 - 5.6e-58 196.8 0.0 9.7e-58 196.0 0.0 1.4 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term GTP_EFTU PF00009.27 EGO59915.1 - 4.7e-35 120.9 0.0 4.7e-35 120.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGO59915.1 - 4.5e-20 71.7 0.0 1.1e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 EGO59915.1 - 9.6e-09 35.0 0.3 4.7e-08 32.8 0.3 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 EGO59915.1 - 1e-07 32.2 0.1 1e-07 32.2 0.1 3.5 4 0 0 4 4 4 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGO59915.1 - 1e-07 32.0 0.1 2.7e-06 27.4 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 EGO59915.1 - 0.00017 21.8 0.0 0.00055 20.1 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EGO59915.1 - 0.0019 18.0 0.0 0.0019 18.0 0.0 2.5 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein Ras PF00071.22 EGO59915.1 - 0.045 13.4 0.0 0.3 10.6 0.0 2.5 1 1 0 1 1 1 0 Ras family RsgA_GTPase PF03193.16 EGO59915.1 - 0.89 9.4 4.2 2.2 8.1 0.1 3.4 3 1 1 4 4 4 0 RsgA GTPase HSP70 PF00012.20 EGO59916.1 - 3e-164 547.5 1.6 3e-164 547.5 1.6 1.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EGO59916.1 - 2.7e-10 39.6 0.0 2e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein BAH PF01426.18 EGO59916.1 - 0.071 13.0 0.1 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 BAH domain Trans_reg_C PF00486.28 EGO59916.1 - 0.081 13.0 0.1 0.36 10.9 0.1 2.1 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal DUF2746 PF10874.8 EGO59916.1 - 0.14 12.6 0.2 0.7 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) Chitin_synth_2 PF03142.15 EGO59917.1 - 5.2e-25 88.1 4.4 2.6e-21 75.9 4.3 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGO59917.1 - 2.6e-16 60.2 5.4 7.1e-16 58.7 5.4 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGO59917.1 - 1.5e-13 51.2 1.3 1.1e-12 48.4 0.3 2.6 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGO59917.1 - 0.0022 17.8 0.3 3.2 7.5 0.0 2.7 3 0 0 3 3 3 2 Glycosyl transferase family 2 SUIM_assoc PF16619.5 EGO59917.1 - 0.0092 16.0 12.1 0.32 11.1 1.3 3.2 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 NINJA_B PF16136.5 EGO59917.1 - 1.3 9.5 4.0 0.81 10.1 0.4 2.4 2 0 0 2 2 2 0 Putative nuclear localisation signal ANAPC_CDC26 PF10471.9 EGO59917.1 - 5.1 8.0 11.4 4.4 8.2 2.7 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 EpuA PF11772.8 EGO59918.1 - 0.045 13.4 0.3 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta MIF4G PF02854.19 EGO59919.1 - 4.2e-57 193.2 0.1 5.8e-29 101.2 0.0 3.9 4 1 0 4 4 4 3 MIF4G domain Upf2 PF04050.14 EGO59919.1 - 7.1e-44 149.8 13.5 7.1e-44 149.8 13.5 2.4 2 0 0 2 2 2 1 Up-frameshift suppressor 2 Astro_capsid_p PF12226.8 EGO59919.1 - 1.8 7.6 17.5 0.087 12.0 11.1 2.0 2 0 0 2 2 2 0 Turkey astrovirus capsid protein KH_1 PF00013.29 EGO59920.1 - 4.3e-30 103.3 1.4 1.3e-07 31.3 0.0 7.2 7 0 0 7 7 7 6 KH domain Mur_ligase_C PF02875.21 EGO59920.1 - 0.13 12.6 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain HAD_2 PF13419.6 EGO59923.1 - 1.4e-10 41.5 0.0 2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGO59923.1 - 3.4e-07 30.8 0.0 2.5e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO59923.1 - 0.0037 17.3 0.0 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like TOM20_plant PF06552.12 EGO59923.1 - 0.04 13.7 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 Med21 PF11221.8 EGO59924.1 - 1.6e-46 158.1 8.1 1.8e-46 158.0 8.1 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 EGO59924.1 - 0.012 15.6 7.9 0.037 14.1 5.6 2.7 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FAM76 PF16046.5 EGO59924.1 - 0.034 13.5 0.3 0.041 13.2 0.3 1.2 1 0 0 1 1 1 0 FAM76 protein AI-2E_transport PF01594.16 EGO59924.1 - 0.12 11.5 0.3 0.16 11.1 0.3 1.2 1 0 0 1 1 1 0 AI-2E family transporter TMF_DNA_bd PF12329.8 EGO59924.1 - 0.26 11.3 12.1 0.069 13.1 8.8 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2034 PF10356.9 EGO59925.1 - 1e-29 103.3 0.0 4.7e-15 55.5 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 EGO59925.1 - 6e-08 32.7 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease AAA_11 PF13086.6 EGO59927.1 - 4.8 6.9 7.3 9.9 5.9 7.3 1.5 1 1 0 1 1 1 0 AAA domain Trypan_PARP PF05887.11 EGO59927.1 - 6 6.9 20.0 1.2 9.1 15.6 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Lon_C PF05362.13 EGO59928.1 - 3.5e-65 219.4 0.1 1e-64 217.9 0.0 1.8 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EGO59928.1 - 2.5e-34 119.0 0.3 9.2e-34 117.1 0.0 2.1 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EGO59928.1 - 6.3e-22 78.4 0.0 1.6e-21 77.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 EGO59928.1 - 1e-08 35.1 0.0 2.6e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 EGO59928.1 - 3.2e-06 27.2 0.0 6.9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGO59928.1 - 4e-06 27.1 0.0 1.2e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGO59928.1 - 4.2e-05 23.3 0.1 0.00054 19.7 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 EGO59928.1 - 0.00011 21.2 0.1 0.00026 20.0 0.0 1.5 2 0 0 2 2 2 1 PrkA AAA domain AAA_22 PF13401.6 EGO59928.1 - 0.00013 22.2 0.0 0.0019 18.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain ClpB_D2-small PF10431.9 EGO59928.1 - 0.0023 17.9 0.2 0.01 15.9 0.2 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 EGO59928.1 - 0.0032 17.9 0.1 0.0032 17.9 0.1 2.8 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 EGO59928.1 - 0.019 14.7 0.0 0.09 12.5 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 EGO59928.1 - 0.022 15.3 0.4 0.076 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGO59928.1 - 0.034 14.2 0.0 0.088 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGO59928.1 - 0.05 14.0 0.0 0.26 11.7 0.0 2.3 2 0 0 2 2 1 0 RNA helicase RsgA_GTPase PF03193.16 EGO59928.1 - 0.074 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase DDHD PF02862.17 EGO59928.1 - 3.2 7.9 7.8 1.1 9.4 0.6 2.8 3 0 0 3 3 3 0 DDHD domain ABC_tran PF00005.27 EGO59928.1 - 3.9 8.0 5.6 1.7 9.1 0.1 2.8 3 0 0 3 3 2 0 ABC transporter Tad PF13400.6 EGO59929.1 - 0.31 11.4 7.2 0.48 10.8 7.2 1.2 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Pkinase PF00069.25 EGO59930.1 - 5.4e-10 39.1 0.0 4.6e-09 36.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO59930.1 - 6.3e-08 32.2 0.0 8.3e-07 28.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase FA_desaturase PF00487.24 EGO59931.1 - 8.4e-19 68.4 9.6 8.4e-19 68.4 9.6 2.0 2 1 1 3 3 3 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGO59931.1 - 2.8e-18 65.8 0.0 7.7e-18 64.4 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HTH_Tnp_Tc5 PF03221.16 EGO59932.1 - 3.3e-20 71.9 3.2 2.8e-08 33.7 0.0 5.9 5 0 0 5 5 5 4 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.11 EGO59932.1 - 1.7e-15 56.6 0.2 4.2e-15 55.4 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EGO59932.1 - 2e-05 24.3 0.5 5.1e-05 23.0 0.5 1.7 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 EGO59932.1 - 0.0037 18.0 3.8 0.0037 18.0 3.8 5.1 6 0 0 6 6 6 1 C2H2-type zinc finger Elf1 PF05129.13 EGO59932.1 - 0.48 10.5 5.4 0.37 10.9 2.4 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2 PF00096.26 EGO59932.1 - 7.1 7.3 26.1 0.046 14.2 3.9 4.4 5 0 0 5 5 5 0 Zinc finger, C2H2 type PAN_1 PF00024.26 EGO59933.1 - 0.002 18.0 0.1 0.0042 17.0 0.1 1.5 1 0 0 1 1 1 1 PAN domain Phage_holin_3_5 PF16085.5 EGO59933.1 - 2.8 8.1 8.4 4.9 7.3 4.8 2.5 2 1 1 3 3 3 0 Bacteriophage holin Hol, superfamily III RSRP PF17069.5 EGO59934.1 - 0.0019 17.9 17.5 0.0019 17.9 17.5 4.8 4 1 1 5 5 5 1 Arginine/Serine-Rich protein 1 PI3K_1B_p101 PF10486.9 EGO59934.1 - 0.45 8.2 5.0 1 7.1 5.0 1.7 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Voldacs PF03517.13 EGO59934.1 - 3.2 7.9 13.6 0.98 9.5 1.1 2.6 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Pribosyltran_N PF13793.6 EGO59935.1 - 6.5e-43 145.4 0.0 2.1e-41 140.5 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGO59935.1 - 6.8e-35 120.8 0.8 6.3e-28 98.0 0.4 3.1 2 1 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGO59935.1 - 2.7e-09 36.7 0.1 0.00013 21.6 0.1 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain UPRTase PF14681.6 EGO59935.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase XPG_I_2 PF12813.7 EGO59936.1 - 4.9e-74 249.0 0.0 9.9e-74 247.9 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing HEAT_2 PF13646.6 EGO59937.1 - 5.4e-28 97.2 3.4 7.6e-13 48.7 0.1 3.5 2 2 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 EGO59937.1 - 3.5e-23 79.9 2.8 0.0055 17.3 0.0 6.4 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EGO59937.1 - 2.5e-10 39.7 2.5 0.15 12.4 0.0 6.0 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 EGO59937.1 - 0.00066 20.1 8.9 5 7.7 0.1 4.9 2 2 3 5 5 5 4 HEAT-like repeat Cnd1 PF12717.7 EGO59937.1 - 0.0045 17.0 0.0 0.79 9.7 0.0 2.9 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF4571 PF15137.6 EGO59937.1 - 0.2 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) TFIIS_C PF01096.18 EGO59938.1 - 1.9e-14 53.2 0.9 1.9e-14 53.2 0.9 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EGO59938.1 - 1.1e-06 28.4 2.8 1.1e-06 28.4 2.8 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit C1_1 PF00130.22 EGO59938.1 - 0.0028 17.5 5.3 0.008 16.0 1.2 2.2 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.19 EGO59938.1 - 0.0097 15.9 5.9 0.41 10.7 0.4 2.3 2 1 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 EGO59938.1 - 0.019 14.6 15.1 0.9 9.3 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain tRNA-synt_1f PF01921.18 EGO59938.1 - 0.047 12.6 1.6 0.11 11.4 0.2 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (K) Lar_restr_allev PF14354.6 EGO59938.1 - 1 9.8 12.1 3.2 8.2 1.5 3.3 2 2 0 2 2 2 0 Restriction alleviation protein Lar RecR PF02132.15 EGO59938.1 - 2 8.1 8.5 0.72 9.5 3.6 2.3 2 1 0 2 2 2 0 RecR protein Zn-ribbon_8 PF09723.10 EGO59938.1 - 2.1 8.5 14.6 1.9 8.7 0.7 2.9 2 1 1 3 3 3 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 EGO59938.1 - 3.2 7.3 12.8 1.1 8.8 0.5 3.4 4 0 0 4 4 4 0 zinc-ribbon domain Zn_ribbon_recom PF13408.6 EGO59938.1 - 7.8 7.1 13.2 5.4 7.6 4.2 3.0 2 2 0 2 2 2 0 Recombinase zinc beta ribbon domain Nipped-B_C PF12830.7 EGO59939.1 - 1.3e-46 158.9 0.6 1.3e-46 158.9 0.6 4.3 5 1 0 5 5 5 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EGO59939.1 - 4.6e-07 30.0 0.5 4.6e-07 30.0 0.5 3.3 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 EGO59939.1 - 1.2e-06 28.3 0.7 0.3 11.5 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat Cnd3 PF12719.7 EGO59939.1 - 1.9e-06 27.3 0.0 0.0078 15.4 0.0 2.5 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 EGO59939.1 - 9.4e-05 21.1 0.9 0.0051 15.4 0.0 3.6 5 0 0 5 5 5 1 Adaptin N terminal region Cnd1 PF12717.7 EGO59939.1 - 0.00041 20.4 3.6 0.026 14.6 0.0 4.2 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Methyltransf_25 PF13649.6 EGO59940.1 - 3.4e-09 37.3 0.0 1.3e-08 35.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO59940.1 - 1.2e-08 35.0 0.0 2.4e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO59940.1 - 1.8e-08 34.9 0.0 5.3e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO59940.1 - 4.9e-06 26.4 0.0 7.2e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO59940.1 - 3.4e-05 24.5 0.0 8.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGO59940.1 - 0.0053 16.1 0.0 0.099 11.9 0.0 2.2 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_4 PF02390.17 EGO59940.1 - 0.016 14.7 0.0 0.036 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase CedA PF10729.9 EGO59940.1 - 0.062 13.1 0.6 0.14 12.0 0.6 1.5 1 0 0 1 1 1 0 Cell division activator CedA Methyltransf_29 PF03141.16 EGO59940.1 - 0.14 10.7 0.0 0.38 9.2 0.0 1.6 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase YqeY PF09424.10 EGO59941.1 - 7.1e-25 87.7 4.9 1e-24 87.2 4.9 1.2 1 0 0 1 1 1 1 Yqey-like protein DUF2017 PF09438.10 EGO59941.1 - 0.022 14.7 3.2 0.032 14.1 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) SapC PF07277.11 EGO59941.1 - 0.083 12.5 0.3 0.12 12.0 0.3 1.1 1 0 0 1 1 1 0 SapC SNF2_N PF00176.23 EGO59942.1 - 1.3e-72 244.5 0.0 2e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO59942.1 - 3.7e-13 49.8 0.0 1.4e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HIRAN PF08797.11 EGO59942.1 - 8.9e-07 28.8 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain DEAD PF00270.29 EGO59942.1 - 1.5e-05 24.9 0.0 4.4e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EGO59942.1 - 0.00021 21.3 0.0 0.0013 18.8 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 EGO59942.1 - 0.0024 17.8 6.5 0.0045 16.9 6.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_5 PF17121.5 EGO59942.1 - 0.011 15.6 4.0 0.025 14.4 4.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WW PF00397.26 EGO59942.1 - 0.024 14.7 0.2 0.06 13.4 0.2 1.7 1 0 0 1 1 1 0 WW domain Prok-RING_4 PF14447.6 EGO59942.1 - 0.04 13.8 2.5 0.097 12.6 2.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGO59942.1 - 0.089 12.7 5.5 0.21 11.5 5.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO59942.1 - 0.44 10.4 7.1 0.23 11.4 3.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO59942.1 - 0.75 10.2 4.6 1.7 9.0 4.6 1.7 1 0 0 1 1 1 0 Ring finger domain Pex2_Pex12 PF04757.14 EGO59944.1 - 7.5e-53 179.4 2.5 9.6e-53 179.1 2.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EGO59944.1 - 4e-05 23.7 2.5 6.7e-05 23.0 2.5 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EGO59944.1 - 0.0013 18.6 4.1 0.0021 17.9 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO59944.1 - 0.0021 18.3 3.9 0.0034 17.7 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGO59944.1 - 0.004 17.0 2.4 0.006 16.4 2.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO59944.1 - 0.044 13.8 2.4 0.084 12.9 2.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EGO59944.1 - 0.15 12.0 3.3 0.26 11.2 3.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 4HBT PF03061.22 EGO59945.1 - 4.3e-13 49.4 0.1 6.2e-13 48.9 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily TFIIA PF03153.13 EGO59945.1 - 0.61 10.0 7.1 0.72 9.8 7.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box PF00646.33 EGO59946.1 - 2.2e-05 24.2 0.0 9.3e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EGO59946.1 - 0.00095 19.0 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.18 EGO59947.1 - 3.8e-67 226.1 0.1 5.9e-67 225.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EGO59947.1 - 1.6e-06 28.2 8.5 0.00032 21.0 0.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO59947.1 - 0.0019 18.9 7.2 0.13 13.1 0.6 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EGO59947.1 - 0.67 10.1 2.6 1.9 8.6 2.5 1.8 1 1 0 1 1 1 0 Aberrant zinc-finger SAP30_Sin3_bdg PF13867.6 EGO59948.1 - 8.7e-08 32.4 0.7 6.2e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 SSP160 PF06933.11 EGO59948.1 - 0.37 8.9 12.0 0.49 8.5 12.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 EGO59948.1 - 0.55 10.2 9.1 0.94 9.5 9.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGO59948.1 - 0.71 9.9 16.5 1.1 9.2 16.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Chitin_synth_1 PF01644.17 EGO59949.1 - 6e-77 257.2 0.1 9.1e-77 256.6 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EGO59949.1 - 1.5e-27 95.4 0.2 3.2e-27 94.3 0.2 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EGO59949.1 - 6.1e-23 81.2 2.4 8.6e-19 67.5 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGO59949.1 - 3.1e-08 33.8 0.4 3.1e-08 33.8 0.4 2.0 3 0 0 3 3 3 1 Glycosyl transferase family group 2 CitMHS PF03600.16 EGO59949.1 - 0.27 10.4 2.8 0.64 9.2 2.8 1.5 1 1 0 1 1 1 0 Citrate transporter NIR_SIR PF01077.22 EGO59950.1 - 2.7e-57 192.7 0.3 1e-50 171.4 0.0 2.9 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EGO59950.1 - 1.9e-32 110.9 0.0 9.8e-16 57.4 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EGO59950.1 - 1.6e-26 93.2 0.0 3.8e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 EGO59950.1 - 1.4e-07 31.5 0.8 4.8e-07 29.7 0.2 2.2 2 1 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Lantibiotic_a PF14867.6 EGO59950.1 - 0.25 11.1 1.3 9.1 6.1 0.2 2.5 2 0 0 2 2 2 0 Lantibiotic alpha CMV_1a PF12467.8 EGO59950.1 - 5.1 7.4 7.8 0.34 11.3 2.5 1.7 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Kei1 PF08552.11 EGO59951.1 - 5.6e-59 199.2 1.7 7e-59 198.9 1.7 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF3810 PF12725.7 EGO59951.1 - 0.074 12.4 1.5 0.12 11.7 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) UNC-93 PF05978.16 EGO59951.1 - 0.08 12.7 1.8 0.12 12.0 0.0 2.0 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 Ribosomal_L24e PF01246.20 EGO59954.1 - 4.6e-28 97.2 6.2 9.7e-28 96.2 6.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e GnsAB_toxin PF08178.11 EGO59954.1 - 0.017 15.1 0.2 6.2 6.8 0.1 2.9 2 1 1 3 3 3 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system Ras PF00071.22 EGO59955.1 - 4.2e-57 192.3 0.1 5.9e-57 191.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO59955.1 - 7.6e-38 129.4 0.0 1.1e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO59955.1 - 2.4e-16 59.7 0.1 3.2e-16 59.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGO59955.1 - 2e-06 27.5 0.0 1.3e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGO59955.1 - 6.4e-05 22.9 0.0 0.036 14.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EGO59955.1 - 7e-05 22.3 0.0 9.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGO59955.1 - 0.00016 21.7 0.0 0.00029 20.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGO59955.1 - 0.0002 20.8 0.1 0.00027 20.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EGO59955.1 - 0.00096 18.9 0.0 0.0021 17.8 0.0 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EGO59955.1 - 0.038 13.8 0.0 0.12 12.1 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein TIR_2 PF13676.6 EGO59955.1 - 0.051 14.2 0.1 0.091 13.4 0.1 1.4 1 0 0 1 1 1 0 TIR domain Nop53 PF07767.11 EGO59956.1 - 2.4e-107 359.8 49.1 2.8e-107 359.6 49.1 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Glyco_hydro_35 PF01301.19 EGO59956.1 - 0.029 14.0 0.2 0.074 12.7 0.2 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 APC_15aa PF05972.11 EGO59956.1 - 0.18 12.1 0.5 0.43 10.9 0.5 1.7 1 0 0 1 1 1 0 APC 15 residue motif V_ATPase_I PF01496.19 EGO59956.1 - 7.1 4.4 12.9 12 3.7 12.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Adaptin_N PF01602.20 EGO59957.1 - 6.1e-123 411.1 11.3 7.6e-123 410.8 11.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGO59957.1 - 3.1e-55 186.6 0.7 3.1e-55 186.6 0.7 3.3 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGO59957.1 - 2.4e-15 56.7 4.8 8.9e-08 32.4 0.2 5.0 3 1 3 6 6 6 5 HEAT repeats HEAT PF02985.22 EGO59957.1 - 5.4e-09 35.5 4.3 0.23 11.8 0.0 5.9 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 EGO59957.1 - 0.00024 21.5 4.6 1.8 9.2 0.2 5.9 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.8 EGO59957.1 - 0.0063 16.1 2.3 1.9 8.0 0.1 3.4 3 1 0 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 EGO59957.1 - 0.012 15.8 1.7 2.1 8.5 0.0 3.6 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Atx10homo_assoc PF09759.9 EGO59957.1 - 0.019 15.0 0.2 9.5 6.3 0.0 4.0 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EGO59957.1 - 0.072 13.2 2.7 2.7 8.2 0.0 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 EGO59957.1 - 0.62 9.8 2.7 25 4.6 0.1 2.7 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) DUF1077 PF06417.12 EGO59958.1 - 2.2e-50 169.6 3.6 2.7e-50 169.3 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) MARVEL PF01284.23 EGO59959.1 - 2.2e-27 95.9 3.9 2.7e-27 95.6 3.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain CD20 PF04103.15 EGO59959.1 - 0.024 14.7 5.6 0.1 12.7 6.0 1.9 2 1 0 2 2 2 0 CD20-like family SLATT_fungal PF18142.1 EGO59959.1 - 1 9.3 4.3 1.8 8.5 4.3 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain IPTL-CTERM PF18203.1 EGO59959.1 - 1.3 9.0 6.4 9.5 6.2 1.1 2.8 2 0 0 2 2 2 0 IPTL-CTERM motif Rad60-SLD_2 PF13881.6 EGO59961.1 - 5.7e-12 45.7 0.0 3.9e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGO59961.1 - 0.00032 20.4 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EGO59961.1 - 0.0022 18.5 0.0 0.0056 17.2 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UMP1 PF05348.11 EGO59962.1 - 1.8e-42 144.3 0.2 4.8e-42 142.9 0.2 1.6 1 1 0 1 1 1 1 Proteasome maturation factor UMP1 ABC_tran PF00005.27 EGO59963.1 - 8.4e-23 81.4 0.0 4.2e-10 40.3 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGO59963.1 - 2.5e-09 37.4 0.2 0.0012 18.7 0.0 3.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGO59963.1 - 6.3e-07 29.6 0.2 0.00086 19.5 0.1 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EGO59963.1 - 0.00011 22.8 0.1 0.062 13.8 0.2 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGO59963.1 - 0.00049 19.8 0.0 0.27 11.0 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 EGO59963.1 - 0.0032 17.2 0.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGO59963.1 - 0.013 15.9 0.0 5 7.5 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 EGO59963.1 - 0.018 15.0 0.0 2.2 8.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 EGO59963.1 - 0.02 14.2 0.0 0.34 10.2 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.6 EGO59963.1 - 0.027 14.8 0.0 4 7.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain SRPRB PF09439.10 EGO59963.1 - 0.052 13.0 0.0 3.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.22 EGO59963.1 - 0.077 13.4 0.0 2.7 8.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 EGO59963.1 - 0.11 12.9 0.0 0.9 10.0 0.0 2.5 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGO59963.1 - 0.17 12.4 0.0 9.1 6.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain Ploopntkinase1 PF18748.1 EGO59963.1 - 0.2 11.1 0.0 0.39 10.2 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 Pyr_redox_2 PF07992.14 EGO59964.1 - 1.2e-43 149.5 0.0 1.7e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO59964.1 - 7.6e-13 48.8 0.0 7.4e-10 39.2 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EGO59964.1 - 2.1e-07 30.0 0.4 4.9e-07 28.8 0.4 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EGO59964.1 - 9.6e-06 25.1 0.5 2.8e-05 23.7 0.5 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EGO59964.1 - 2.4e-05 24.7 0.0 6.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGO59964.1 - 0.0021 17.5 0.8 0.0045 16.4 0.8 1.5 1 0 0 1 1 1 1 EF hand PTPS PF01242.19 EGO59964.1 - 0.087 12.8 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase Pyr_redox_3 PF13738.6 EGO59964.1 - 0.12 11.6 0.0 11 5.2 0.1 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase bVLRF1 PF18826.1 EGO59964.1 - 0.18 11.7 0.1 0.36 10.7 0.1 1.4 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor PRK PF00485.18 EGO59965.1 - 1.9e-57 194.2 0.0 2.9e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 EGO59965.1 - 8.8e-41 139.6 0.0 1.4e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 EGO59965.1 - 2.2e-05 25.0 0.0 5.5e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGO59965.1 - 3.8e-05 24.1 0.6 0.0042 17.5 0.9 3.2 2 1 0 2 2 2 1 AAA domain CPT PF07931.12 EGO59965.1 - 7.3e-05 22.7 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 EGO59965.1 - 0.00011 22.4 0.0 0.00065 19.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGO59965.1 - 0.0015 18.3 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGO59965.1 - 0.0036 17.8 0.7 0.0081 16.7 0.2 1.8 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 EGO59965.1 - 0.007 15.6 0.1 0.019 14.2 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_29 PF13555.6 EGO59965.1 - 0.0093 15.7 0.2 0.059 13.1 0.2 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGO59965.1 - 0.012 15.0 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Cytidylate_kin PF02224.18 EGO59965.1 - 0.012 15.4 0.4 0.14 11.9 0.0 2.4 2 1 0 2 2 2 0 Cytidylate kinase AAA_22 PF13401.6 EGO59965.1 - 0.029 14.7 0.0 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGO59965.1 - 0.03 14.4 0.0 0.095 12.8 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 EGO59965.1 - 0.043 13.7 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 EGO59965.1 - 0.087 12.8 0.0 0.39 10.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGO59965.1 - 0.17 11.9 0.0 0.75 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain HET PF06985.11 EGO59966.1 - 6e-31 107.8 0.0 1.2e-30 106.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 EGO59966.1 - 5.1e-20 71.8 2.1 1.1e-19 70.7 0.3 2.2 2 1 1 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO59966.1 - 1.8e-15 57.1 0.3 4.7e-15 55.8 0.3 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO59966.1 - 1.2e-07 31.8 0.6 2.1e-07 31.1 0.6 1.3 1 0 0 1 1 1 1 KR domain CLTH PF10607.9 EGO59967.1 - 1e-31 109.8 0.3 1.3e-31 109.4 0.3 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EGO59967.1 - 4.4e-11 42.3 0.0 1e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 LisH ETC_C1_NDUFA4 PF04800.12 EGO59968.1 - 6.9e-32 109.6 0.5 1e-31 109.0 0.5 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2188 PF09954.9 EGO59968.1 - 0.038 14.1 0.1 0.097 12.8 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) F1F0-ATPsyn_F PF10791.9 EGO59969.1 - 1.2e-40 137.9 0.3 1.4e-40 137.7 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi SUIM_assoc PF16619.5 EGO59970.1 - 0.32 11.1 12.6 0.064 13.3 6.8 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Aminotran_1_2 PF00155.21 EGO59971.1 - 1.5e-13 50.6 0.0 3.9e-08 32.9 0.0 2.5 2 1 0 2 2 2 2 Aminotransferase class I and II Sua5_yciO_yrdC PF01300.18 EGO59971.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Telomere recombination MOZ_SAS PF01853.18 EGO59972.1 - 3.3e-81 271.2 0.1 4.7e-81 270.7 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EGO59972.1 - 8.4e-22 76.5 3.9 1.6e-21 75.6 3.9 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EGO59972.1 - 9e-18 63.9 0.0 2.4e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EGO59972.1 - 0.00019 21.8 0.0 0.00038 20.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO59972.1 - 0.005 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DDRGK PF09756.9 EGO59972.1 - 0.043 13.4 0.1 0.043 13.4 0.1 3.1 2 2 0 2 2 2 0 DDRGK domain RNase_T PF00929.24 EGO59973.1 - 8.1e-14 52.5 0.0 1.4e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EGO59973.1 - 0.001 18.8 0.0 0.0026 17.5 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease Plasmodium_Vir PF05795.11 EGO59973.1 - 3.1 7.1 9.5 6.3 6.1 9.5 1.5 1 1 0 1 1 1 0 Plasmodium vivax Vir protein CMAS PF02353.20 EGO59974.1 - 6.6e-58 196.2 0.0 1.3e-55 188.6 0.0 2.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EGO59974.1 - 9.8e-10 39.0 0.0 1.9e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO59974.1 - 2.6e-07 31.2 0.0 5.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO59974.1 - 4.6e-06 26.6 0.0 7.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO59974.1 - 0.00016 22.4 0.0 0.00038 21.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGO59974.1 - 0.00073 19.4 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGO59974.1 - 0.00076 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGO59974.1 - 0.054 13.2 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Pkinase_fungal PF17667.1 EGO59975.1 - 4.6e-21 75.1 0.0 5.6e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGO59975.1 - 0.088 12.2 0.0 0.17 11.2 0.0 1.4 2 0 0 2 2 2 0 Protein kinase domain TRAPPC-Trs85 PF12739.7 EGO59976.1 - 1.1e-120 403.4 0.3 3.3e-120 401.8 0.2 1.7 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Polysacc_deac_1 PF01522.21 EGO59977.1 - 9.5e-13 48.1 0.0 1.9e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EGO59977.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) INCENP_ARK-bind PF03941.15 EGO59978.1 - 2.6e-15 56.1 0.2 2.1e-14 53.2 0.1 2.8 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region zf-C3HC4_2 PF13923.6 EGO59979.1 - 4.6e-10 39.2 18.7 1.1e-09 38.0 13.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO59979.1 - 1.4e-07 31.2 20.8 2.9e-07 30.2 14.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.27 EGO59979.1 - 8.8e-07 28.5 0.4 1.6e-06 27.7 0.4 1.5 1 0 0 1 1 1 1 SAP domain zf-C3HC4_3 PF13920.6 EGO59979.1 - 7.5e-06 25.7 11.1 7.5e-06 25.7 11.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EGO59979.1 - 1.6e-05 24.6 8.8 1.9e-05 24.4 5.3 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 EGO59979.1 - 1.8e-05 24.7 11.9 1.8e-05 24.7 11.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGO59979.1 - 2.6e-05 24.1 13.6 2.6e-05 24.1 13.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGO59979.1 - 8.8e-05 22.8 20.7 0.00025 21.3 14.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_10 PF16685.5 EGO59979.1 - 0.0006 19.9 6.2 0.0011 19.1 6.2 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 EGO59979.1 - 0.00071 19.4 15.8 0.015 15.2 11.8 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 EGO59979.1 - 0.00073 19.7 0.0 0.0033 17.5 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-C3HC4_4 PF15227.6 EGO59979.1 - 0.0015 18.6 13.9 0.0015 18.6 13.9 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EGO59979.1 - 0.0036 17.5 9.4 0.0036 17.5 9.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGO59979.1 - 1.1 9.3 5.9 3.1 7.9 5.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Mob_synth_C PF06463.13 EGO59979.1 - 1.6 8.7 4.4 3.2 7.7 4.4 1.5 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C MFS_1 PF07690.16 EGO59980.1 - 6.3e-33 114.1 24.2 6.3e-33 114.1 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 EGO59981.1 - 0.00023 20.3 0.0 0.00031 19.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain G-alpha PF00503.20 EGO59982.1 - 3.3e-116 388.3 0.2 3.8e-116 388.1 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGO59982.1 - 4e-16 58.9 0.2 5.4e-10 39.0 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGO59982.1 - 6.6e-05 22.4 0.6 0.033 13.5 0.2 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGO59982.1 - 0.00098 19.3 0.3 1 9.6 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EGO59982.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cullin PF00888.22 EGO59983.1 - 2.2e-193 644.3 5.2 3e-193 643.8 5.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGO59983.1 - 2.9e-26 91.3 5.0 1.1e-25 89.4 5.0 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 EGO59983.1 - 0.0046 17.5 0.7 0.03 14.9 0.7 2.4 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal AnfG_VnfG PF03139.15 EGO59983.1 - 0.014 15.4 2.2 0.74 9.9 0.6 3.1 2 0 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit Rrf2 PF02082.20 EGO59983.1 - 0.018 15.3 0.0 0.055 13.8 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator ARL2_Bind_BART PF11527.8 EGO59983.1 - 0.72 10.0 4.7 1.4 9.1 0.1 3.4 3 1 0 3 3 3 0 The ARF-like 2 binding protein BART Mit_KHE1 PF10173.9 EGO59986.1 - 2.9e-65 219.9 0.1 4.6e-65 219.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Ion_trans_2 PF07885.16 EGO59987.1 - 0.00017 21.5 1.9 0.00048 20.0 0.0 2.2 2 0 0 2 2 2 1 Ion channel PDZ_1 PF12812.7 EGO59988.1 - 7.2e-51 170.1 0.0 8e-36 121.9 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 EGO59988.1 - 2.3e-26 93.5 0.5 1.3e-21 78.1 0.0 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 EGO59988.1 - 7.5e-15 55.0 0.1 3e-06 27.5 0.0 4.4 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 EGO59988.1 - 1.1e-09 37.9 0.0 0.067 13.1 0.0 3.8 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 EGO59988.1 - 1.4e-08 35.0 0.0 0.0029 17.9 0.0 4.0 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 EGO59988.1 - 0.0085 16.0 0.0 0.51 10.3 0.1 3.3 4 0 0 4 4 4 1 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 EGO59988.1 - 0.014 15.1 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Peptidase_S46 PF10459.9 EGO59988.1 - 0.034 12.8 0.1 0.06 12.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase S46 DnaJ PF00226.31 EGO59989.1 - 4.1e-18 65.2 2.2 7.3e-18 64.5 2.2 1.4 1 0 0 1 1 1 1 DnaJ domain AA_permease PF00324.21 EGO59990.1 - 1.2e-110 370.4 37.6 1.3e-110 370.2 37.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO59990.1 - 3.9e-17 62.2 41.2 5.3e-17 61.8 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease DnaJ_C PF01556.18 EGO59992.1 - 2.7e-40 137.9 0.1 3.7e-40 137.4 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGO59992.1 - 9.5e-26 89.7 1.1 1.5e-25 89.1 1.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGO59992.1 - 1.8e-09 37.8 22.5 4e-09 36.7 22.5 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGO59992.1 - 0.0052 16.7 4.6 0.0052 16.7 4.6 2.7 1 1 1 2 2 2 1 Tryptophan RNA-binding attenuator protein inhibitory protein Snf7 PF03357.21 EGO59993.1 - 5.1e-18 65.3 23.7 8.7e-18 64.5 23.7 1.4 1 0 0 1 1 1 1 Snf7 BUD22 PF09073.10 EGO59993.1 - 0.52 9.6 15.6 0.67 9.2 15.6 1.1 1 0 0 1 1 1 0 BUD22 PCEMA1 PF07418.11 EGO59993.1 - 1.2 8.6 13.5 0.91 9.0 12.0 1.4 1 1 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 DUF948 PF06103.11 EGO59993.1 - 3 8.2 8.4 12 6.2 2.3 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) WRNPLPNID PF15017.6 EGO59993.1 - 6.4 7.7 18.0 19 6.2 18.0 1.8 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box DUF1840 PF08895.11 EGO59993.1 - 9.4 6.6 19.0 0.25 11.7 9.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) MCM PF00493.23 EGO59994.1 - 4.2e-104 346.6 1.1 5.6e-104 346.1 0.5 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EGO59994.1 - 8.9e-38 129.0 0.4 1.6e-37 128.2 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EGO59994.1 - 2.1e-33 114.8 0.2 4.8e-33 113.6 0.2 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EGO59994.1 - 5.6e-25 87.6 0.1 5.6e-25 87.6 0.1 2.5 3 0 0 3 3 3 1 MCM AAA-lid domain MCM_N PF14551.6 EGO59994.1 - 5.3e-21 75.2 0.0 1.9e-20 73.4 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGO59994.1 - 1.4e-07 31.1 0.0 7.8e-07 28.7 0.1 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGO59994.1 - 0.00053 19.7 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 EGO59994.1 - 0.00087 19.2 0.1 0.0029 17.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGO59994.1 - 0.02 14.9 0.1 0.11 12.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Peptidase_M20 PF01546.28 EGO59994.1 - 0.02 14.6 0.0 0.1 12.2 0.0 2.1 2 1 0 2 2 2 0 Peptidase family M20/M25/M40 Peptidase_C14 PF00656.22 EGO59995.1 - 0.0012 18.8 0.1 0.0088 16.0 0.1 2.0 1 1 0 1 1 1 1 Caspase domain Methyltransf_2 PF00891.18 EGO59996.1 - 1.8e-27 96.0 0.0 4e-27 94.9 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase domain Glyco_hydro_70 PF02324.16 EGO59996.1 - 0.13 10.5 0.0 0.18 9.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 PRIMA1 PF16101.5 EGO59997.1 - 0.023 14.7 3.7 0.023 14.7 3.7 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 EGO59997.1 - 0.19 11.8 2.4 0.35 10.9 2.4 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Cu_bind_like PF02298.17 EGO59997.1 - 0.23 11.5 0.0 0.58 10.2 0.0 1.6 1 1 0 1 1 1 0 Plastocyanin-like domain EB PF01683.18 EGO59998.1 - 0.00018 21.8 23.9 0.15 12.4 4.0 3.2 3 0 0 3 3 3 3 EB module FAD_binding_3 PF01494.19 EGO60000.1 - 1.5e-91 307.3 0.0 6.4e-91 305.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGO60000.1 - 1.3e-58 197.7 0.0 2.2e-58 197.0 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 EGO60000.1 - 2.9e-05 23.3 0.4 5.7e-05 22.4 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EGO60000.1 - 0.00018 20.3 0.3 0.00028 19.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Collagen PF01391.18 EGO60000.1 - 0.00035 20.3 8.1 0.00063 19.5 8.1 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Pyr_redox_3 PF13738.6 EGO60000.1 - 0.0012 18.2 0.2 0.0019 17.5 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO60000.1 - 0.0015 17.8 0.4 0.0037 16.5 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGO60000.1 - 0.003 16.8 0.0 0.0071 15.6 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EGO60000.1 - 0.0036 16.7 0.2 0.006 16.0 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO60000.1 - 0.0073 16.5 0.1 0.043 14.0 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGO60000.1 - 0.014 14.5 0.1 0.024 13.7 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 EGO60000.1 - 0.024 13.5 0.0 0.048 12.5 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 EGO60000.1 - 0.027 13.5 0.7 0.048 12.7 0.4 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EGO60000.1 - 0.045 13.1 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Papilloma_E5A PF05776.12 EGO60001.1 - 1.1 9.7 6.4 0.14 12.5 1.6 2.0 2 0 0 2 2 2 0 Papillomavirus E5A protein zf-RING_5 PF14634.6 EGO60002.1 - 2.1e-05 24.4 1.9 2.1e-05 24.4 1.9 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO60002.1 - 0.0019 18.1 1.6 0.0019 18.1 1.6 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO60002.1 - 0.0036 17.1 1.1 0.0036 17.1 1.1 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO60002.1 - 0.0042 17.4 2.5 0.0042 17.4 2.5 3.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 EGO60002.1 - 0.0055 16.7 3.9 0.0055 16.7 3.9 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-Sec23_Sec24 PF04810.15 EGO60002.1 - 0.02 15.0 0.2 0.02 15.0 0.2 3.0 3 1 0 3 3 3 0 Sec23/Sec24 zinc finger zf-C3HC4_4 PF15227.6 EGO60002.1 - 0.14 12.3 0.6 0.14 12.3 0.6 3.3 5 0 0 5 5 5 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 EGO60002.1 - 4.2 7.1 9.2 0.94 9.2 0.1 3.2 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type p450 PF00067.22 EGO60003.1 - 7.6e-75 252.4 0.0 9.7e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 EGO60003.1 - 8.6e-32 110.5 0.0 1.5e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGO60003.1 - 2.7e-26 92.5 0.0 7.4e-26 91.1 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 EGO60003.1 - 4.5e-13 49.8 0.0 1.1e-12 48.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.11 EGO60003.1 - 0.051 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 NrdI Flavodoxin like Flavodoxin_5 PF12724.7 EGO60003.1 - 0.053 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain Glyco_hydro_cc PF11790.8 EGO60004.1 - 2.9e-74 249.6 0.1 4.3e-74 249.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Transferase PF02458.15 EGO60004.1 - 4.2e-12 45.4 0.0 0.00031 19.5 0.0 4.0 4 0 0 4 4 4 2 Transferase family FAD_oxidored PF12831.7 EGO60004.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Kinesin PF00225.23 EGO60006.1 - 9.7e-53 179.2 0.0 1.3e-52 178.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGO60006.1 - 1.2e-10 41.5 0.0 2.4e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 Microtubule binding NRBF2 PF08961.10 EGO60006.1 - 0.011 15.3 0.9 0.011 15.3 0.9 2.0 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 EGO60006.1 - 0.17 12.5 0.2 0.17 12.5 0.2 2.6 2 1 1 3 3 3 0 Initiation control protein YabA DUF87 PF01935.17 EGO60006.1 - 1.9 8.5 4.6 11 6.1 0.6 3.2 3 1 0 4 4 4 0 Helicase HerA, central domain Herpes_BLRF2 PF05812.12 EGO60006.1 - 2 8.5 5.8 0.86 9.8 0.2 2.4 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Jnk-SapK_ap_N PF09744.9 EGO60006.1 - 2.9 8.1 15.8 0.58 10.4 7.8 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 SH3_9 PF14604.6 EGO60007.1 - 6.6e-06 25.9 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGO60007.1 - 3e-05 23.6 0.0 4.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGO60007.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Tropomyosin PF00261.20 EGO60008.1 - 0.00035 20.0 19.7 0.014 14.8 7.1 3.0 1 1 2 3 3 3 2 Tropomyosin Tropomyosin_1 PF12718.7 EGO60008.1 - 0.00052 20.2 16.9 0.00067 19.8 16.9 1.1 1 0 0 1 1 1 1 Tropomyosin like CLZ PF16526.5 EGO60008.1 - 0.014 15.8 3.6 0.014 15.8 3.6 2.9 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SHE3 PF17078.5 EGO60008.1 - 0.017 14.9 8.0 0.05 13.3 8.0 1.7 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 BBP1_C PF15272.6 EGO60008.1 - 0.046 13.6 6.1 0.067 13.0 5.9 1.4 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal CENP-H PF05837.12 EGO60008.1 - 0.057 13.8 18.0 0.026 14.9 13.6 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Pullulanase_Ins PF18494.1 EGO60008.1 - 0.071 13.6 1.8 0.73 10.4 0.8 2.3 1 1 1 2 2 2 0 Pullulanase Ins domain XhlA PF10779.9 EGO60008.1 - 0.13 12.5 6.1 17 5.7 0.6 3.1 1 1 2 3 3 3 0 Haemolysin XhlA XPC-binding PF09280.11 EGO60008.1 - 0.15 11.8 9.7 0.5 10.1 2.9 3.3 2 1 0 2 2 2 0 XPC-binding domain Cluap1 PF10234.9 EGO60008.1 - 0.17 11.3 14.9 0.21 11.0 14.9 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 ATG16 PF08614.11 EGO60008.1 - 0.17 12.1 23.4 0.22 11.7 16.8 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 EGO60008.1 - 0.18 12.0 7.1 0.56 10.4 1.0 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Tektin PF03148.14 EGO60008.1 - 0.23 10.2 15.9 0.35 9.6 15.9 1.2 1 0 0 1 1 1 0 Tektin family TPR_MLP1_2 PF07926.12 EGO60008.1 - 0.45 10.6 24.6 6.3 6.9 0.5 2.5 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Golgin_A5 PF09787.9 EGO60008.1 - 0.49 9.8 15.9 0.69 9.3 15.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMF_DNA_bd PF12329.8 EGO60008.1 - 0.62 10.1 13.1 0.54 10.3 1.2 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4472 PF14739.6 EGO60008.1 - 0.64 10.8 17.3 7.4 7.4 8.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Spc7 PF08317.11 EGO60008.1 - 0.67 8.8 17.9 0.73 8.6 17.9 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 EGO60008.1 - 0.72 9.6 13.2 1.4 8.7 9.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) IFT57 PF10498.9 EGO60008.1 - 0.92 8.4 10.9 0.3 10.0 6.2 1.7 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Pox_A_type_inc PF04508.12 EGO60008.1 - 0.98 9.4 0.0 0.98 9.4 0.0 2.8 4 0 0 4 4 2 0 Viral A-type inclusion protein repeat Ax_dynein_light PF10211.9 EGO60008.1 - 1 9.3 14.8 3 7.7 2.1 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Atg14 PF10186.9 EGO60008.1 - 1.2 8.2 13.2 1.5 7.9 13.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 EGO60008.1 - 1.2 9.2 20.5 2.2 8.3 8.9 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 EGO60008.1 - 1.4 8.1 8.4 1.6 7.9 8.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein PIN_2 PF10130.9 EGO60008.1 - 1.8 8.8 7.3 1.2 9.4 2.8 2.2 1 1 1 2 2 2 0 PIN domain YabA PF06156.13 EGO60008.1 - 2 9.1 8.8 3.7 8.2 0.3 2.3 1 1 0 2 2 2 0 Initiation control protein YabA DUF1664 PF07889.12 EGO60008.1 - 2.6 8.1 7.4 2.5 8.1 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GIT_CC PF16559.5 EGO60008.1 - 2.7 7.9 14.6 1 9.2 0.9 3.2 1 1 2 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Lge1 PF11488.8 EGO60008.1 - 2.7 8.2 9.9 2.4 8.4 1.1 2.7 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 UPF0242 PF06785.11 EGO60008.1 - 3.4 7.7 14.6 5.7 7.0 14.6 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus COG2 PF06148.11 EGO60008.1 - 4.3 7.4 11.4 0.9 9.6 1.0 2.8 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 bZIP_2 PF07716.15 EGO60008.1 - 6.1 7.0 18.5 1.6 8.9 1.2 3.9 1 1 3 4 4 4 0 Basic region leucine zipper TolA_bind_tri PF16331.5 EGO60008.1 - 8.2 6.6 18.9 0.46 10.6 2.9 3.1 1 1 0 2 2 2 0 TolA binding protein trimerisation SlyX PF04102.12 EGO60008.1 - 8.6 7.1 21.3 3.1 8.5 4.9 2.6 1 1 1 2 2 2 0 SlyX Phage_GPO PF05929.11 EGO60008.1 - 9.3 5.8 17.4 1.2e+02 2.2 17.6 1.9 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase MAD PF05557.13 EGO60010.1 - 3.2e-05 22.5 5.3 3.7e-05 22.3 5.3 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF3584 PF12128.8 EGO60010.1 - 0.00051 17.7 4.6 0.00059 17.5 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 EGO60010.1 - 0.0021 18.5 11.0 0.024 15.1 7.2 3.5 1 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein CENP-Q PF13094.6 EGO60010.1 - 0.0023 18.1 7.3 0.0034 17.6 7.3 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Fez1 PF06818.15 EGO60010.1 - 0.0029 18.1 8.8 0.0094 16.4 8.8 1.7 1 1 0 1 1 1 1 Fez1 GAS PF13851.6 EGO60010.1 - 0.0061 15.9 10.8 0.0061 15.9 10.8 1.7 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Spectrin PF00435.21 EGO60010.1 - 0.0094 16.4 8.6 1.3 9.5 6.7 2.6 1 1 2 3 3 3 2 Spectrin repeat CdvA PF18822.1 EGO60010.1 - 0.014 15.2 5.4 1.7 8.5 2.3 3.0 2 1 1 3 3 3 0 CdvA-like coiled-coil domain EzrA PF06160.12 EGO60010.1 - 0.014 13.6 6.3 0.19 9.9 6.4 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Pox_A_type_inc PF04508.12 EGO60010.1 - 0.018 14.9 8.6 0.02 14.7 0.5 4.0 5 0 0 5 5 4 0 Viral A-type inclusion protein repeat Lebercilin PF15619.6 EGO60010.1 - 0.018 14.7 10.6 0.037 13.7 10.6 1.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease CC2-LZ PF16516.5 EGO60010.1 - 0.028 14.8 10.2 0.36 11.2 3.6 3.0 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TMF_TATA_bd PF12325.8 EGO60010.1 - 0.048 13.9 10.2 2.2 8.5 9.2 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Striatin PF08232.12 EGO60010.1 - 0.061 13.9 4.6 0.076 13.6 4.6 1.3 1 0 0 1 1 1 0 Striatin family V_ATPase_I PF01496.19 EGO60010.1 - 0.064 11.2 1.5 0.065 11.1 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 EGO60010.1 - 0.073 12.4 8.2 0.11 11.9 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bacillus_HBL PF05791.11 EGO60010.1 - 0.09 12.6 6.6 2 8.2 0.4 2.5 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) BLOC1_2 PF10046.9 EGO60010.1 - 0.098 13.0 9.0 1.4 9.3 6.3 2.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rab5-bind PF09311.11 EGO60010.1 - 0.1 12.0 11.2 0.15 11.4 9.4 1.9 1 1 1 2 2 2 0 Rabaptin-like protein Prefoldin PF02996.17 EGO60010.1 - 0.12 12.3 10.7 0.89 9.5 8.7 2.7 1 1 0 2 2 2 0 Prefoldin subunit DUF641 PF04859.12 EGO60010.1 - 0.16 12.3 8.8 0.67 10.3 2.5 2.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF4201 PF13870.6 EGO60010.1 - 0.17 11.6 7.7 0.28 10.9 4.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 EGO60010.1 - 0.17 10.7 11.6 0.25 10.2 10.6 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Sec34 PF04136.15 EGO60010.1 - 0.2 11.6 6.0 0.59 10.0 4.4 2.3 1 1 0 2 2 2 0 Sec34-like family Tropomyosin_1 PF12718.7 EGO60010.1 - 0.2 11.8 13.1 0.11 12.6 10.7 1.8 1 1 0 1 1 1 0 Tropomyosin like PRKG1_interact PF15898.5 EGO60010.1 - 0.21 12.5 8.2 3.6 8.5 7.9 2.5 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain WD40_alt PF14077.6 EGO60010.1 - 0.33 10.8 2.0 0.66 9.9 0.7 2.3 1 1 1 2 2 1 0 Alternative WD40 repeat motif ABC_tran_CTD PF16326.5 EGO60010.1 - 0.34 11.2 10.4 0.93 9.8 9.3 2.4 1 1 0 1 1 1 0 ABC transporter C-terminal domain DivIC PF04977.15 EGO60010.1 - 0.34 10.7 14.7 0.066 13.0 2.1 2.7 2 1 1 3 3 2 0 Septum formation initiator Fmp27_WPPW PF10359.9 EGO60010.1 - 0.37 9.6 6.9 0.71 8.7 6.3 1.6 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4461 PF14688.6 EGO60010.1 - 0.37 10.5 4.9 0.3 10.8 3.7 1.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4461) CENP-F_leu_zip PF10473.9 EGO60010.1 - 0.37 10.8 14.1 2.9 7.9 12.6 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 EGO60010.1 - 0.39 10.9 12.1 0.46 10.7 10.2 1.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 EGO60010.1 - 0.44 10.7 6.3 1.9 8.7 2.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 EGO60010.1 - 0.45 10.9 13.5 0.13 12.6 4.9 3.2 1 1 3 4 4 3 0 Csm1 N-terminal domain AAA_13 PF13166.6 EGO60010.1 - 0.46 9.1 9.4 1.5 7.4 7.4 2.2 1 1 1 2 2 2 0 AAA domain Occludin_ELL PF07303.13 EGO60010.1 - 0.47 11.2 3.9 1.7 9.4 2.6 2.3 1 1 2 3 3 2 0 Occludin homology domain Shugoshin_N PF07558.11 EGO60010.1 - 0.48 10.3 4.4 1.5 8.8 1.2 2.5 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region CALCOCO1 PF07888.11 EGO60010.1 - 0.49 9.2 12.4 1.2 7.9 10.9 1.9 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like RRP36 PF06102.12 EGO60010.1 - 0.54 10.2 4.7 0.79 9.7 4.7 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF2730 PF10805.8 EGO60010.1 - 0.54 10.4 5.4 1.2 9.3 5.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) YabA PF06156.13 EGO60010.1 - 0.59 10.8 7.6 5.9 7.6 6.6 2.6 1 1 1 2 2 2 0 Initiation control protein YabA ADIP PF11559.8 EGO60010.1 - 0.64 10.1 13.8 0.38 10.8 7.7 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 EGO60010.1 - 0.64 10.1 15.8 0.46 10.5 5.2 3.1 2 1 2 4 4 3 0 TATA element modulatory factor 1 DNA binding Snapin_Pallidin PF14712.6 EGO60010.1 - 0.65 10.5 9.7 0.39 11.2 7.3 1.9 2 0 0 2 2 1 0 Snapin/Pallidin JIP_LZII PF16471.5 EGO60010.1 - 0.72 10.1 9.4 1.2 9.4 0.7 3.4 3 1 0 3 3 3 0 JNK-interacting protein leucine zipper II Prominin PF05478.11 EGO60010.1 - 0.75 7.7 6.6 0.82 7.6 6.6 1.3 1 1 0 1 1 1 0 Prominin Baculo_PEP_C PF04513.12 EGO60010.1 - 0.81 9.7 8.5 8.2 6.5 8.5 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 EGO60010.1 - 0.81 10.0 15.6 1.4e+02 2.8 15.6 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Mod_r PF07200.13 EGO60010.1 - 0.81 9.8 10.2 1.4 9.0 8.6 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TolA_bind_tri PF16331.5 EGO60010.1 - 1.1 9.4 14.7 2.5 8.2 12.3 2.5 2 1 1 3 3 2 0 TolA binding protein trimerisation DUF16 PF01519.16 EGO60010.1 - 1.1 9.8 12.6 5.8 7.5 9.1 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 Phage_GP20 PF06810.11 EGO60010.1 - 1.2 9.0 13.6 1.1 9.1 7.0 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF1664 PF07889.12 EGO60010.1 - 1.2 9.2 6.4 3.7 7.6 4.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 EGO60010.1 - 1.2 8.9 7.2 1.7 8.4 6.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DHR10 PF18595.1 EGO60010.1 - 1.4 9.0 15.6 1.1 9.3 12.8 2.3 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 EGO60010.1 - 1.5 9.3 7.4 2.7 8.4 2.5 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) HemX PF04375.14 EGO60010.1 - 1.7 7.9 14.7 0.97 8.7 11.5 1.8 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2203 PF09969.9 EGO60010.1 - 1.9 9.2 6.5 10 6.9 6.1 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF745 PF05335.13 EGO60010.1 - 2.2 7.9 13.3 5.8 6.6 0.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF745) SlyX PF04102.12 EGO60010.1 - 2.6 8.7 14.8 1.9 9.1 7.5 3.4 1 1 1 3 3 3 0 SlyX APG6_N PF17675.1 EGO60010.1 - 2.7 8.5 15.8 2.3 8.7 13.0 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 EGO60010.1 - 3 8.1 12.0 18 5.6 3.5 2.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin_2 PF14523.6 EGO60010.1 - 3.7 8.0 10.8 9.5 6.7 8.6 2.2 1 1 0 2 2 2 0 Syntaxin-like protein ATG16 PF08614.11 EGO60010.1 - 4.6 7.4 16.0 5.8 7.1 13.9 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MerR-DNA-bind PF09278.11 EGO60010.1 - 6.1 7.5 8.1 5.5 7.6 1.9 2.5 1 1 1 2 2 2 0 MerR, DNA binding FAM76 PF16046.5 EGO60010.1 - 7.9 5.7 8.2 74 2.5 8.0 1.9 1 1 0 1 1 1 0 FAM76 protein DUF3847 PF12958.7 EGO60010.1 - 9 6.5 10.6 9.4 6.4 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) Spc24 PF08286.11 EGO60010.1 - 9.2 6.6 12.3 1.5e+02 2.7 12.3 2.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 PKcGMP_CC PF16808.5 EGO60011.1 - 0.021 14.7 10.3 4.2 7.3 0.3 3.5 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pox_A_type_inc PF04508.12 EGO60011.1 - 0.036 13.9 5.0 1.1 9.3 0.0 3.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat RAWUL PF16207.5 EGO60011.1 - 0.04 14.6 1.3 2.6 8.8 0.5 2.8 2 1 0 2 2 2 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like DUF445 PF04286.12 EGO60011.1 - 0.093 12.5 8.8 0.12 12.1 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Med6 PF04934.14 EGO60011.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 MED6 mediator sub complex component ATG16 PF08614.11 EGO60011.1 - 0.19 11.9 30.3 0.3 11.3 29.8 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Hemerythrin PF01814.23 EGO60011.1 - 0.2 12.3 6.2 0.084 13.5 2.7 2.0 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Fib_alpha PF08702.10 EGO60011.1 - 0.38 10.9 13.5 1.4 9.1 1.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 EGO60011.1 - 0.42 8.5 9.3 0.6 8.0 9.3 1.2 1 0 0 1 1 1 0 Prominin TolA_bind_tri PF16331.5 EGO60011.1 - 1 9.4 20.9 0.64 10.1 8.0 3.6 3 1 0 3 3 3 0 TolA binding protein trimerisation ApoC-I PF04691.12 EGO60011.1 - 1 9.3 5.9 13 5.8 0.2 3.3 2 1 1 3 3 3 0 Apolipoprotein C-I (ApoC-1) PolyA_pol PF01743.20 EGO60011.1 - 2.3 8.6 5.8 1.1 9.7 2.7 2.0 1 1 1 2 2 2 0 Poly A polymerase head domain Mut7-C PF01927.16 EGO60011.1 - 4.8 7.3 8.7 2.3 8.3 4.1 2.1 1 1 1 2 2 2 0 Mut7-C RNAse domain DUF507 PF04368.13 EGO60011.1 - 5.7 6.8 12.2 0.93 9.4 4.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF507) Borrelia_P83 PF05262.11 EGO60011.1 - 7.6 4.9 20.6 12 4.3 20.6 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein NPV_P10 PF05531.12 EGO60013.1 - 0.00088 19.7 6.0 0.0096 16.4 0.6 6.8 3 2 2 5 5 5 2 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 EGO60013.1 - 0.014 15.6 2.3 0.014 15.6 2.3 4.3 3 1 2 5 5 5 0 Tropomyosin like TTRAP PF14203.6 EGO60013.1 - 0.059 13.4 2.4 0.11 12.5 0.3 2.6 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein DAHP_snth_FXD PF18152.1 EGO60013.1 - 0.12 12.3 7.9 9.8 6.1 0.4 4.7 3 1 1 4 4 4 0 DAHP synthase ferredoxin-like domain Glyco_hydro_31 PF01055.26 EGO60013.1 - 0.24 10.5 4.9 0.06 12.5 1.5 1.6 2 0 0 2 2 2 0 Glycosyl hydrolases family 31 DUF3349 PF11829.8 EGO60013.1 - 2.9 8.7 7.5 19 6.1 1.6 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF3349) NPR3 PF03666.13 EGO60015.1 - 0.16 10.7 7.9 0.2 10.4 7.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 EGO60015.1 - 0.24 10.1 5.5 0.33 9.7 5.5 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EGO60015.1 - 0.86 7.8 5.9 1.1 7.4 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 EGO60015.1 - 1.5 7.2 8.5 1.9 6.9 8.5 1.2 1 0 0 1 1 1 0 Macoilin family Catalase PF00199.19 EGO60017.1 - 5e-176 585.4 0.0 6e-176 585.2 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGO60017.1 - 2.1e-11 43.8 0.0 4.4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive AA_permease PF00324.21 EGO60019.1 - 9.5e-139 463.0 47.8 1.2e-138 462.8 47.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGO60019.1 - 1.4e-39 136.1 51.2 1.9e-39 135.8 51.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2781 PF10914.8 EGO60020.1 - 7.9e-33 113.9 7.8 1.8e-32 112.8 7.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Putative_PNPOx PF01243.20 EGO60021.1 - 1.2e-05 25.4 0.0 9.8e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase adh_short PF00106.25 EGO60022.1 - 5.3e-27 94.6 0.0 6.5e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO60022.1 - 3.2e-19 69.4 0.0 4.1e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO60022.1 - 1.5e-07 31.5 0.2 2.1e-07 31.0 0.2 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO60022.1 - 9.2e-07 28.6 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGO60022.1 - 0.003 17.5 0.0 0.0063 16.4 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGO60022.1 - 0.0049 16.0 0.0 0.0067 15.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EGO60022.1 - 0.014 14.8 0.1 0.017 14.5 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Mce4_CUP1 PF11887.8 EGO60022.1 - 0.014 14.8 0.2 0.027 13.9 0.2 1.4 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative CLP1_P PF16575.5 EGO60022.1 - 0.058 13.2 0.0 7.5 6.3 0.0 2.3 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APH PF01636.23 EGO60024.1 - 4.2e-59 200.4 0.1 5.8e-59 199.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_3 PF07859.13 EGO60025.1 - 7.5e-40 137.0 0.1 3.3e-26 92.5 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGO60025.1 - 0.0022 17.0 0.0 0.0031 16.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 EGO60025.1 - 0.015 14.2 0.3 0.097 11.5 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family Methyltrans_Mon PF14314.6 EGO60025.1 - 0.095 10.7 0.0 0.12 10.3 0.0 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase AAA PF00004.29 EGO60026.1 - 4.4e-16 59.5 0.0 8.4e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGO60026.1 - 0.025 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain SET PF00856.28 EGO60030.1 - 0.024 15.0 0.0 0.031 14.7 0.0 1.2 1 0 0 1 1 1 0 SET domain GDPD PF03009.17 EGO60031.1 - 6e-12 45.8 0.0 8.3e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Tricorn_C1 PF14684.6 EGO60033.1 - 0.05 13.7 0.3 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Tricorn protease C1 domain EELM2 PF15863.5 EGO60033.1 - 0.56 10.3 3.9 6.4 6.9 0.2 3.4 4 0 0 4 4 4 0 Extended EGL-27 and MTA1 homology domain Metal_resist PF13801.6 EGO60033.1 - 0.71 10.1 3.4 14 5.9 3.2 2.3 2 0 0 2 2 2 0 Heavy-metal resistance zf-CCHC_2 PF13696.6 EGO60033.1 - 0.91 9.4 5.7 2.1 8.2 0.7 2.7 2 0 0 2 2 2 0 Zinc knuckle Zap1_zf2 PF18217.1 EGO60034.1 - 2.4 8.2 4.9 0.94 9.5 0.4 2.1 2 0 0 2 2 2 0 Zap1 zinc finger 2 Peptidase_M20 PF01546.28 EGO60035.1 - 1.5e-34 119.5 0.0 3.1e-34 118.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGO60035.1 - 1.6e-11 44.1 0.0 2.8e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGO60035.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Yippee-Mis18 PF03226.14 EGO60036.1 - 1.2e-18 67.3 0.0 1.9e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF678 PF05077.12 EGO60036.1 - 0.06 13.5 0.6 5.5 7.2 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF678) RIG-I_C-RD PF11648.8 EGO60036.1 - 0.064 13.5 0.2 0.61 10.3 0.1 2.0 2 0 0 2 2 2 0 C-terminal domain of RIG-I BIR PF00653.21 EGO60036.1 - 0.12 13.0 0.6 12 6.7 0.1 2.9 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain His_biosynth PF00977.21 EGO60038.1 - 6.5e-49 166.4 0.1 2e-48 164.8 0.1 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EGO60038.1 - 1.3e-19 70.8 0.0 2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EGO60038.1 - 1.4e-09 38.1 0.0 8.2e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EGO60038.1 - 4.2e-08 33.0 0.0 1.2e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.17 EGO60038.1 - 0.013 14.6 0.1 0.034 13.2 0.0 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.13 EGO60038.1 - 0.041 13.6 0.2 0.44 10.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 TFIIIC_sub6 PF10419.9 EGO60039.1 - 4.3e-29 100.2 0.0 7.8e-29 99.4 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Vps62 PF06101.11 EGO60040.1 - 3.1e-10 39.0 0.1 6e-10 38.0 0.1 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 DUF1302 PF06980.11 EGO60040.1 - 0.097 11.3 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) Peptidase_S8 PF00082.22 EGO60041.1 - 1.8e-30 106.2 20.9 4e-30 105.1 20.2 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGO60041.1 - 2.5e-10 40.9 0.2 8.8e-10 39.1 0.2 1.9 1 1 0 1 1 1 1 Peptidase inhibitor I9 FAD_binding_3 PF01494.19 EGO60043.1 - 5.4e-07 29.2 2.0 0.002 17.5 0.1 3.0 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 EGO60043.1 - 0.00036 20.2 0.2 0.00064 19.4 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO60043.1 - 0.0014 18.8 0.2 0.0038 17.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGO60043.1 - 0.059 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EGO60043.1 - 0.059 12.6 0.1 0.096 11.9 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2026 PF09641.10 EGO60043.1 - 0.11 12.1 0.0 15 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2026) Trp_halogenase PF04820.14 EGO60043.1 - 0.2 10.5 0.1 0.28 10.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 EGO60043.1 - 0.2 10.9 0.3 0.3 10.3 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1013 PF06242.11 EGO60043.1 - 0.22 11.5 0.0 0.49 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) FSA_C PF10479.9 EGO60045.1 - 4 5.5 9.4 4.7 5.2 9.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF5301 PF17225.3 EGO60045.1 - 4 7.9 8.5 1.1 9.8 5.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5300) Staph_haemo PF05480.11 EGO60045.1 - 6.2 6.7 5.9 34 4.3 0.2 3.1 1 1 2 3 3 3 0 Staphylococcus haemolytic protein PMI_typeI PF01238.21 EGO60046.1 - 6e-133 443.6 0.1 7.2e-133 443.4 0.1 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 EGO60046.1 - 0.00032 20.6 0.0 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 EGO60046.1 - 0.011 15.4 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Cupin domain RPA43_OB PF17875.1 EGO60047.1 - 4.1e-39 134.0 1.5 4.1e-39 134.0 1.5 4.0 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EGO60047.1 - 6e-08 33.0 0.0 1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 SOG2 PF10428.9 EGO60047.1 - 2.5 7.2 11.4 4.6 6.3 11.4 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Raftlin PF15250.6 EGO60047.1 - 4.9 5.8 19.3 0.37 9.5 12.5 2.1 2 0 0 2 2 2 0 Raftlin BAF1_ABF1 PF04684.13 EGO60047.1 - 9.1 5.2 29.8 5.2 6.0 25.4 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor NmrA PF05368.13 EGO60049.1 - 2.7e-27 95.8 0.0 3.6e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO60049.1 - 0.00022 21.2 0.0 0.00051 20.0 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGO60049.1 - 0.00082 18.9 0.0 0.0058 16.1 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EGO60049.1 - 0.0015 18.5 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGO60049.1 - 0.027 13.9 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DAO PF01266.24 EGO60049.1 - 0.084 12.4 0.0 3.9 7.0 0.0 2.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Polysacc_synt_2 PF02719.15 EGO60049.1 - 0.17 11.0 0.0 1.4 8.0 0.0 1.9 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein NACHT PF05729.12 EGO60050.1 - 2.3e-06 27.6 0.1 1.3e-05 25.2 0.1 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EGO60050.1 - 0.0072 16.7 0.1 0.03 14.7 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EGO60050.1 - 0.015 15.8 0.0 0.055 14.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 EGO60050.1 - 0.02 14.8 0.2 0.053 13.4 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGO60050.1 - 0.034 14.4 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGO60050.1 - 0.048 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EGO60050.1 - 0.081 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGO60050.1 - 0.11 13.1 0.0 0.61 10.6 0.0 2.3 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EGO60050.1 - 0.19 12.2 0.0 0.46 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 EGO60050.1 - 0.32 11.5 1.6 3.4 8.1 0.0 2.7 4 0 0 4 4 4 0 AAA domain Sugar_tr PF00083.24 EGO60051.1 - 6.3e-82 275.8 19.8 2e-45 155.5 1.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGO60051.1 - 3.1e-30 105.3 45.8 8e-27 94.1 21.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Erythro-docking PF09277.11 EGO60051.1 - 0.029 14.3 0.5 0.058 13.3 0.5 1.4 1 0 0 1 1 1 0 Erythronolide synthase, docking Asp_Glu_race PF01177.22 EGO60052.1 - 0.00037 20.4 0.0 0.00073 19.4 0.0 1.4 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Actin PF00022.19 EGO60053.1 - 9.3e-112 373.6 0.0 5.9e-111 370.9 0.0 1.8 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 EGO60053.1 - 0.021 14.1 0.1 0.04 13.1 0.1 1.4 1 0 0 1 1 1 0 Putative actin-like family MreB_Mbl PF06723.13 EGO60053.1 - 0.04 12.7 0.0 0.43 9.3 0.0 2.4 1 1 0 1 1 1 0 MreB/Mbl protein Pkinase PF00069.25 EGO60054.1 - 4.5e-63 213.1 0.0 7.8e-63 212.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO60054.1 - 1.9e-30 106.1 0.0 4.7e-30 104.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO60054.1 - 0.009 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGO60054.1 - 0.015 14.6 0.0 0.032 13.5 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 EGO60054.1 - 0.051 13.5 0.1 0.66 9.9 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family Arf PF00025.21 EGO60055.1 - 7.3e-72 240.5 0.2 8.4e-72 240.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGO60055.1 - 2.5e-14 53.5 0.0 3.7e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGO60055.1 - 4e-13 49.3 0.0 4.6e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EGO60055.1 - 6.6e-13 48.5 1.1 4.6e-09 35.9 0.4 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGO60055.1 - 4e-12 45.9 0.0 4.8e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGO60055.1 - 6e-10 38.9 0.1 7.6e-10 38.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGO60055.1 - 0.00014 21.9 0.0 0.00041 20.4 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase CorC_HlyC PF03471.17 EGO60055.1 - 0.0068 16.4 0.2 0.3 11.1 0.2 2.8 2 1 0 2 2 2 1 Transporter associated domain 6PF2K PF01591.18 EGO60055.1 - 0.015 14.6 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF1325 PF07039.11 EGO60056.1 - 1.8e-35 121.9 0.0 3.2e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain AAA_24 PF13479.6 EGO60056.1 - 0.056 13.2 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain AA_permease_2 PF13520.6 EGO60057.1 - 8.8e-68 229.1 43.8 1e-67 228.8 43.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO60057.1 - 4.9e-23 81.5 39.1 6.1e-23 81.1 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease Amidinotransf PF02274.17 EGO60058.1 - 0.00062 19.0 0.0 0.05 12.7 0.0 2.8 2 1 0 2 2 2 1 Amidinotransferase PAD_porph PF04371.15 EGO60058.1 - 0.094 12.0 0.0 0.78 9.0 0.0 2.0 2 0 0 2 2 2 0 Porphyromonas-type peptidyl-arginine deiminase Pro_isomerase PF00160.21 EGO60062.1 - 6.5e-34 117.5 0.0 9.5e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EGO60062.1 - 4.1e-17 61.8 0.0 7.5e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 EGO60064.1 - 1.2e-07 31.7 7.1 1.9e-07 31.1 7.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_16 PF10294.9 EGO60065.1 - 4.2e-20 72.2 0.0 6e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EGO60065.1 - 0.00043 20.9 0.0 0.00099 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGO60065.1 - 0.0013 18.6 0.1 0.0031 17.3 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EGO60065.1 - 0.0053 16.6 0.0 0.018 14.8 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGO60065.1 - 0.0092 15.5 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGO60065.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EGO60065.1 - 0.05 13.4 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EGO60065.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_3 PF01596.17 EGO60065.1 - 0.13 11.4 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_12 PF08242.12 EGO60065.1 - 0.14 13.0 0.1 0.33 11.7 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S24e PF01282.19 EGO60066.1 - 1.1e-35 121.4 0.1 1.9e-35 120.6 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S24e KCT2 PF17818.1 EGO60068.1 - 0.15 12.2 0.2 0.32 11.1 0.2 1.5 1 1 0 1 1 1 0 Keratinocyte-associated gene product CCDC66 PF15236.6 EGO60068.1 - 0.25 11.2 7.2 0.35 10.7 7.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 SH3_15 PF18346.1 EGO60071.1 - 0.036 14.4 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 Mind bomb SH3 repeat domain REV PF00424.18 EGO60071.1 - 0.15 12.1 5.2 1.8 8.7 0.8 3.5 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) GTP_cyclohydro2 PF00925.20 EGO60072.1 - 1.6e-61 206.7 0.0 2.5e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Glyco_hydro_6 PF01341.17 EGO60074.1 - 2.1e-98 329.8 0.1 2.7e-98 329.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 FAD_binding_3 PF01494.19 EGO60075.1 - 9.8e-14 51.3 0.3 3.8e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain GramPos_pilinD3 PF16570.5 EGO60075.1 - 0.093 13.5 0.1 0.17 12.6 0.1 1.4 1 0 0 1 1 1 0 Gram-positive pilin backbone subunit 3, Cna-B-like domain Methyltransf_23 PF13489.6 EGO60076.1 - 8.7e-15 54.9 0.0 1.6e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO60076.1 - 2.9e-07 31.1 0.1 2.3e-06 28.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO60076.1 - 3.7e-05 24.3 0.0 0.00012 22.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO60076.1 - 0.0044 17.7 0.0 0.14 12.9 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGO60076.1 - 0.0097 15.2 0.1 2.5 7.3 0.1 2.2 2 0 0 2 2 2 2 O-methyltransferase domain PrmA PF06325.13 EGO60076.1 - 0.021 14.2 0.4 0.049 13.0 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGO60076.1 - 0.039 13.5 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 EGO60076.1 - 0.053 13.3 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Epimerase PF01370.21 EGO60079.1 - 7.3e-13 48.5 0.0 2.4e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EGO60079.1 - 2e-10 40.7 0.0 2.3e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 EGO60079.1 - 1.7e-09 37.8 0.0 2.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGO60079.1 - 8.3e-07 28.7 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGO60079.1 - 7.5e-05 21.9 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Hexapep PF00132.24 EGO60080.1 - 1.9e-09 36.9 9.0 0.00016 21.3 2.7 4.6 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGO60080.1 - 0.00025 20.7 1.8 0.25 11.1 0.8 3.1 2 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase Rhodanese PF00581.20 EGO60081.1 - 0.00021 21.8 0.0 0.00028 21.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Enolase_like_N PF18374.1 EGO60081.1 - 2.8 7.4 5.5 2.1 7.8 0.2 2.6 3 0 0 3 3 3 0 Enolase N-terminal domain-like Sugar_tr PF00083.24 EGO60083.1 - 2.4e-80 270.6 19.5 2.7e-80 270.4 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO60083.1 - 1.6e-24 86.5 23.7 4.1e-20 72.0 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGO60083.1 - 0.00052 18.7 0.3 0.00052 18.7 0.3 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein DUF4293 PF14126.6 EGO60083.1 - 0.19 12.0 4.7 0.18 12.1 2.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Peptidase_M43 PF05572.13 EGO60084.1 - 1.8e-17 63.7 2.1 2e-17 63.5 0.7 1.7 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 EGO60084.1 - 2.3e-06 28.1 0.0 6.4e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EGO60084.1 - 4.1e-06 27.1 6.7 4e-05 23.8 6.7 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EGO60084.1 - 7.9e-05 22.4 3.4 0.00027 20.6 3.3 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EGO60084.1 - 0.0011 18.0 0.7 0.0021 17.1 0.7 1.5 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M10 PF00413.24 EGO60084.1 - 0.0081 16.0 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.6 EGO60084.1 - 0.027 14.4 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF2198 PF09964.9 EGO60087.1 - 0.01 15.9 1.5 0.014 15.5 0.9 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2198) DnaJ PF00226.31 EGO60088.1 - 4.7e-08 33.0 0.6 9.7e-08 32.0 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain MFS_1 PF07690.16 EGO60089.1 - 2.2e-25 89.3 40.6 2e-24 86.2 16.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily NDUF_B7 PF05676.13 EGO60090.1 - 6.2e-30 102.7 6.6 7.5e-30 102.5 6.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CRR7 PF12095.8 EGO60092.1 - 0.12 12.8 0.1 5 7.6 0.0 2.8 3 0 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Ribosomal_60s PF00428.19 EGO60093.1 - 0.00046 20.7 0.0 0.00079 20.0 0.0 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Mus7 PF09462.10 EGO60094.1 - 0.099 11.5 0.3 0.12 11.2 0.3 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family CBM-like PF14683.6 EGO60094.1 - 0.13 12.1 7.4 0.058 13.3 3.5 2.1 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain III Ten_N PF06484.12 EGO60095.1 - 5.1 6.9 14.5 0.89 9.4 5.6 2.1 1 1 0 2 2 2 0 Teneurin Intracellular Region Pap_E4 PF02711.14 EGO60097.1 - 0.078 13.9 0.5 0.078 13.9 0.5 2.3 2 1 1 3 3 3 0 E4 protein BcsB PF03170.13 EGO60102.1 - 0.072 11.5 0.0 0.098 11.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit RNA_pol_3_Rpc31 PF11705.8 EGO60103.1 - 0.0053 17.1 9.0 0.0053 17.1 9.0 3.1 3 0 0 3 3 3 2 DNA-directed RNA polymerase III subunit Rpc31 TLP-20 PF06088.11 EGO60103.1 - 6 6.7 15.5 0.37 10.7 5.3 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) HATPase_c PF02518.26 EGO60106.1 - 2.8e-25 89.0 0.0 9.1e-25 87.3 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGO60106.1 - 1.5e-24 86.3 0.2 2.9e-24 85.4 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGO60106.1 - 4e-17 62.0 0.1 9.5e-17 60.8 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EGO60106.1 - 7.6e-11 42.2 0.0 6.1e-10 39.3 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EGO60106.1 - 9.7e-09 35.2 0.0 7.5e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EGO60106.1 - 6.6e-06 26.3 0.0 0.00027 21.2 0.0 3.0 3 0 0 3 3 3 1 PAS fold PAS_3 PF08447.12 EGO60106.1 - 0.024 14.9 0.2 0.11 12.8 0.1 2.2 2 0 0 2 2 2 0 PAS fold FAD_binding_3 PF01494.19 EGO60108.1 - 3.3e-12 46.3 0.1 0.00019 20.8 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.24 EGO60108.1 - 5.9e-08 32.2 0.2 1.3e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO60108.1 - 1.8e-07 30.7 0.1 4.2e-07 29.5 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO60108.1 - 3.3e-07 30.4 0.0 6.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO60108.1 - 4.9e-06 26.4 0.2 2e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGO60108.1 - 3.8e-05 22.6 0.0 5.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 EGO60108.1 - 7.1e-05 22.1 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EGO60108.1 - 0.00014 22.3 0.6 0.00055 20.4 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGO60108.1 - 0.00029 20.3 0.3 0.00054 19.4 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO60108.1 - 0.00097 18.5 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGO60108.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EGO60108.1 - 0.026 13.8 0.1 0.043 13.0 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 EGO60108.1 - 0.099 11.9 0.1 0.39 9.9 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EGO60108.1 - 0.13 11.3 0.0 0.63 9.0 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Glyco_hydro_11 PF00457.17 EGO60109.1 - 1.3e-80 269.3 20.1 1.5e-80 269.0 20.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF309 PF03745.14 EGO60110.1 - 2.3 7.9 4.6 16 5.3 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF309) DUF4276 PF14103.6 EGO60111.1 - 0.16 12.2 0.1 0.21 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) TSP_1 PF00090.19 EGO60114.1 - 0.38 11.0 0.3 0.38 11.0 0.3 2.0 2 1 1 3 3 3 0 Thrombospondin type 1 domain HET PF06985.11 EGO60115.1 - 2.2e-21 76.8 0.0 3.3e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1467 PF07330.12 EGO60116.1 - 4.1 7.4 6.5 6.7 6.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) HSP20 PF00011.21 EGO60117.1 - 5.7e-18 64.9 2.6 2.7e-12 46.7 2.6 2.7 2 1 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGO60117.1 - 3e-07 29.9 1.6 1.3e-06 27.8 1.6 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Tim54 PF11711.8 EGO60117.1 - 0.0029 16.5 1.6 0.0036 16.1 1.6 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 WW PF00397.26 EGO60118.1 - 0.0015 18.6 0.6 0.0037 17.3 0.6 1.8 1 0 0 1 1 1 1 WW domain CSTF_C PF14304.6 EGO60118.1 - 0.07 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal XAP5 PF04921.14 EGO60118.1 - 1 9.1 3.6 1.5 8.6 3.6 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF5553 PF17707.1 EGO60118.1 - 7.9 5.9 6.6 2.4 7.6 0.9 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5553) CCDC53 PF10152.9 EGO60118.1 - 8.3 6.8 9.3 0.36 11.3 2.7 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex NAD_binding_8 PF13450.6 EGO60119.1 - 1.6e-09 37.9 0.0 3.7e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO60119.1 - 1.6e-05 24.7 0.2 2.6e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGO60119.1 - 2.3e-05 23.7 0.2 5.6e-05 22.4 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO60119.1 - 8.8e-05 21.9 0.0 0.00018 20.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGO60119.1 - 0.00018 20.3 0.3 0.00032 19.5 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EGO60119.1 - 0.00023 20.6 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGO60119.1 - 0.00043 19.6 0.1 0.00067 19.0 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 EGO60119.1 - 0.0033 16.3 0.1 0.0047 15.8 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EGO60119.1 - 0.0048 16.2 0.0 0.0088 15.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 EGO60119.1 - 0.0081 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EGO60119.1 - 0.017 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 EGO60119.1 - 0.023 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 EGO60119.1 - 0.08 13.2 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF3176 PF11374.8 EGO60120.1 - 1.6e-19 70.1 3.3 1.6e-19 70.1 3.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) MrpF_PhaF PF04066.13 EGO60120.1 - 2.6 8.5 6.0 12 6.4 1.1 2.7 2 0 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) GAS PF13851.6 EGO60121.1 - 0.0015 17.9 1.8 0.0018 17.7 1.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 EGO60121.1 - 0.011 16.1 0.9 0.017 15.5 0.9 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Virulence_RhuM PF13310.6 EGO60121.1 - 0.027 13.7 0.2 0.033 13.4 0.2 1.1 1 0 0 1 1 1 0 Virulence protein RhuM family Fusion_gly PF00523.18 EGO60121.1 - 0.03 12.6 0.2 0.032 12.5 0.2 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Transglut_prok PF09017.10 EGO60121.1 - 0.033 13.6 0.0 0.043 13.2 0.0 1.0 1 0 0 1 1 1 0 Microbial transglutaminase Erp_C PF06780.11 EGO60121.1 - 0.049 13.6 0.4 0.061 13.3 0.4 1.2 1 0 0 1 1 1 0 Erp protein C-terminus Aldo_ket_red PF00248.21 EGO60125.1 - 5e-49 167.1 0.0 5.8e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.11 EGO60126.1 - 1.8e-24 86.8 0.4 3.9e-24 85.7 0.4 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 EGO60128.1 - 7.4e-36 123.4 0.0 9.5e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO60128.1 - 4.7e-18 65.6 0.0 6e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO60128.1 - 8.9e-10 38.8 0.0 5.8e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO60128.1 - 3.6e-05 23.4 0.1 0.00016 21.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGO60128.1 - 0.0054 16.6 0.1 0.011 15.6 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGO60128.1 - 0.011 15.1 0.0 0.095 12.1 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 EGO60128.1 - 0.014 14.8 1.2 0.029 13.8 1.0 1.5 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 EGO60128.1 - 0.027 14.7 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 EGO60128.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Cucumo_2B PF03263.13 EGO60129.1 - 0.48 10.9 7.5 0.18 12.3 4.5 1.9 2 0 0 2 2 2 0 Cucumovirus protein 2B Atrophin-1 PF03154.15 EGO60130.1 - 0.018 13.4 6.4 0.021 13.1 6.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3450 PF11932.8 EGO60130.1 - 0.033 13.5 4.7 0.043 13.1 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1840 PF08895.11 EGO60130.1 - 0.044 14.1 4.7 0.062 13.6 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF3824 PF12868.7 EGO60130.1 - 0.11 13.2 4.7 0.18 12.5 4.7 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Connexin PF00029.19 EGO60130.1 - 0.37 10.5 2.2 0.49 10.1 2.2 1.1 1 0 0 1 1 1 0 Connexin DUF3915 PF13054.6 EGO60130.1 - 0.83 9.6 6.3 1.5 8.9 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF3682 PF12446.8 EGO60130.1 - 1.1 9.8 6.8 1.5 9.3 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) CRA PF06589.11 EGO60130.1 - 2.1 8.5 15.6 14 5.8 14.2 2.1 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) LCD1 PF09798.9 EGO60130.1 - 6.9 5.1 19.6 8.6 4.7 19.6 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein SOG2 PF10428.9 EGO60131.1 - 0.73 9.0 20.3 0.019 14.2 13.6 1.7 2 0 0 2 2 2 0 RAM signalling pathway protein Ank_4 PF13637.6 EGO60132.1 - 4.9e-12 46.1 1.7 3.1e-05 24.4 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGO60132.1 - 1.3e-11 44.9 0.0 0.00017 22.1 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EGO60132.1 - 6.7e-10 39.0 0.0 0.00081 19.7 0.1 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGO60132.1 - 1.5e-08 34.7 0.2 0.018 15.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 EGO60132.1 - 7.5e-08 32.2 0.0 1.9e-06 27.7 0.1 2.8 2 1 0 2 2 2 1 KilA-N domain Ank_3 PF13606.6 EGO60132.1 - 3.6e-07 30.0 0.1 0.5 11.1 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat eIF3_subunit PF08597.10 EGO60132.1 - 0.0015 18.5 16.3 0.0016 18.4 3.7 2.3 1 1 1 2 2 2 2 Translation initiation factor eIF3 subunit TTRAP PF14203.6 EGO60132.1 - 0.28 11.2 2.4 13 5.8 0.1 3.7 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein DUF4510 PF14971.6 EGO60132.1 - 2.1 8.7 5.4 1.3 9.4 1.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4510) CSG2 PF16965.5 EGO60135.1 - 6.6e-09 35.2 4.4 2e-08 33.6 4.3 1.7 1 1 0 1 1 1 1 Ceramide synthase regulator EamA PF00892.20 EGO60135.1 - 1.6e-08 34.8 33.8 2.7e-07 30.8 0.7 3.0 3 0 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 EGO60135.1 - 0.0004 20.0 6.2 0.0004 20.0 6.2 1.5 2 0 0 2 2 2 1 Solute carrier family 35 TraL PF07178.11 EGO60135.1 - 0.6 10.6 5.5 19 5.8 0.0 3.3 1 1 1 2 2 2 0 TraL protein CDH1_2_SANT_HL1 PF18375.1 EGO60136.1 - 0.019 15.6 0.6 0.046 14.4 0.6 1.6 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 Secretin_N_2 PF07655.13 EGO60136.1 - 0.058 13.9 4.8 0.13 12.9 4.8 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain HORMA PF02301.18 EGO60136.1 - 5.1 6.6 6.8 5.3 6.6 0.0 2.3 1 1 1 2 2 2 0 HORMA domain DnaB_bind PF10410.9 EGO60139.1 - 0.22 11.7 1.8 1.4e+02 2.8 0.0 4.1 5 0 0 5 5 5 0 DnaB-helicase binding domain of primase GBP_PSP PF02425.15 EGO60139.1 - 4.7 6.9 15.9 18 5.1 0.1 5.1 5 0 0 5 5 5 0 Paralytic/GBP/PSP peptide COQ7 PF03232.13 EGO60140.1 - 0.015 15.0 0.1 0.018 14.8 0.1 1.1 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Ureide_permease PF07168.11 EGO60141.1 - 0.043 12.6 8.2 0.043 12.6 8.2 1.0 1 0 0 1 1 1 0 Ureide permease DUF4629 PF15442.6 EGO60141.1 - 0.076 13.2 11.4 0.082 13.1 11.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) Connexin PF00029.19 EGO60141.1 - 0.11 12.3 8.7 0.11 12.3 8.7 1.0 1 0 0 1 1 1 0 Connexin DUF4670 PF15709.5 EGO60141.1 - 0.13 11.5 18.4 0.15 11.4 18.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) TRAP_alpha PF03896.16 EGO60141.1 - 1.1 8.4 8.0 1.1 8.4 8.0 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit YqfQ PF14181.6 EGO60141.1 - 2.1 8.5 9.4 2.3 8.4 9.4 1.0 1 0 0 1 1 1 0 YqfQ-like protein FAM176 PF14851.6 EGO60141.1 - 2.1 8.0 8.9 2.3 7.9 8.9 1.1 1 0 0 1 1 1 0 FAM176 family RNA_pol_Rpc4 PF05132.14 EGO60141.1 - 2.3 8.6 8.2 2.6 8.5 8.2 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 EGO60141.1 - 2.7 7.1 4.2 2.8 7.1 4.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EGO60141.1 - 2.9 6.6 7.5 2.9 6.5 7.5 1.0 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 EGO60141.1 - 3.5 7.7 11.0 3.8 7.6 11.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDC45 PF02724.14 EGO60141.1 - 3.6 5.8 11.0 4 5.6 11.0 1.0 1 0 0 1 1 1 0 CDC45-like protein AIF_C PF14721.6 EGO60141.1 - 3.9 7.8 7.4 4.2 7.7 7.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EOS1 PF12326.8 EGO60141.1 - 4.3 7.2 5.1 5 7.0 5.1 1.0 1 0 0 1 1 1 0 N-glycosylation protein Serinc PF03348.15 EGO60141.1 - 9.4 5.0 6.5 9.7 5.0 6.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) BPL_N PF09825.9 EGO60142.1 - 0.057 12.5 5.8 0.057 12.5 5.8 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Cadherin_tail PF15974.5 EGO60143.1 - 0.028 14.8 6.1 0.033 14.5 6.1 1.1 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region RNA_polI_A34 PF08208.11 EGO60143.1 - 0.35 10.9 14.9 0.4 10.8 14.9 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Pho86 PF11124.8 EGO60143.1 - 0.99 8.8 2.8 1.2 8.6 2.8 1.0 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Tim54 PF11711.8 EGO60143.1 - 2 7.1 11.1 2.1 7.0 11.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 EGO60143.1 - 7.2 5.3 4.6 7.3 5.2 4.6 1.0 1 0 0 1 1 1 0 Presenilin 2OG-FeII_Oxy_2 PF13532.6 EGO60145.1 - 3.3e-15 56.8 0.0 6.8e-14 52.5 0.0 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 EGO60146.1 - 2.9e-18 66.2 3.9 0.0002 21.9 0.0 5.9 3 1 4 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO60146.1 - 1.4e-16 60.6 10.9 8.6e-07 29.4 0.1 6.6 8 0 0 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO60146.1 - 5.6e-14 50.9 5.7 0.00034 20.8 0.0 8.0 8 1 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 EGO60146.1 - 5.8e-14 52.0 6.8 1.4e-05 25.3 0.2 6.3 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EGO60146.1 - 6.3e-11 42.2 10.9 0.022 15.2 0.0 7.6 8 0 0 8 8 8 2 Ankyrin repeat F-box-like PF12937.7 EGO60146.1 - 0.037 13.9 0.1 0.073 13.0 0.1 1.5 1 0 0 1 1 1 0 F-box-like Ank_2 PF12796.7 EGO60147.1 - 3.7e-05 24.2 0.0 1.5 9.5 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGO60147.1 - 0.0014 18.9 0.2 0.23 11.8 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGO60147.1 - 0.0058 17.2 0.4 0.4 11.3 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO60147.1 - 0.025 15.1 0.0 1.2e+02 3.7 0.0 5.6 6 0 0 6 6 6 0 Ankyrin repeat SLAC1 PF03595.17 EGO60149.1 - 1e-40 140.0 34.2 1.2e-40 139.8 34.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel HET PF06985.11 EGO60150.1 - 2.2e-25 89.7 0.0 4.1e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Baculo_LEF5 PF04838.12 EGO60151.1 - 0.018 15.1 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 Retrotran_gag_3 PF14244.6 EGO60152.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type NOA36 PF06524.12 EGO60153.1 - 1.4 8.2 3.4 1.9 7.8 3.4 1.1 1 0 0 1 1 1 0 NOA36 protein Retrotran_gag_3 PF14244.6 EGO60154.1 - 0.059 13.2 0.0 0.075 12.9 0.0 1.3 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type TackOD1 PF18551.1 EGO60157.1 - 0.2 11.3 0.0 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 FA_desaturase PF00487.24 EGO60159.1 - 1.3e-16 61.2 25.0 1.3e-16 61.2 25.0 1.7 1 1 1 2 2 2 1 Fatty acid desaturase AAA PF00004.29 EGO60160.1 - 2.6e-14 53.8 0.0 4.5e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGO60160.1 - 0.00036 21.0 0.0 0.0011 19.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGO60160.1 - 0.00092 19.5 0.1 0.0041 17.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EGO60160.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 EGO60160.1 - 0.095 12.4 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 EGO60160.1 - 0.12 12.9 0.0 0.37 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain NAS PF03059.16 EGO60162.1 - 5.3e-65 219.5 0.0 6.4e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.6 EGO60162.1 - 0.0017 18.2 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO60162.1 - 0.0068 17.0 0.0 0.018 15.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO60162.1 - 0.016 15.9 0.0 0.034 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Guanylin PF02058.15 EGO60162.1 - 0.089 13.3 0.2 0.23 11.9 0.2 1.6 1 0 0 1 1 1 0 Guanylin precursor ATPgrasp_N PF18130.1 EGO60163.1 - 1.3e-20 73.7 0.0 3.3e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 EGO60163.1 - 1e-07 31.7 0.0 3.7e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGO60163.1 - 1.3e-05 24.9 0.0 5.2e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus 4HBT PF03061.22 EGO60164.1 - 1.1e-08 35.3 0.1 3.4e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_2 PF13279.6 EGO60165.1 - 0.0036 17.8 0.0 0.0056 17.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF3455 PF11937.8 EGO60168.1 - 4.8e-43 147.3 0.0 5.7e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) C2 PF00168.30 EGO60170.1 - 5.4e-13 49.1 0.0 8.5e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain zf-MIZ PF02891.20 EGO60171.1 - 2.1e-06 27.3 2.9 1.1e-05 25.1 2.9 2.1 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EGO60171.1 - 0.0027 17.5 0.1 0.0084 15.9 0.1 1.9 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit AT_hook PF02178.19 EGO60171.1 - 1.9 8.7 7.7 5.8 7.1 7.7 1.9 1 0 0 1 1 1 0 AT hook motif Abhydrolase_6 PF12697.7 EGO60172.1 - 7.3e-20 72.5 0.2 8.5e-20 72.3 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO60172.1 - 1.3e-07 31.1 0.0 1.8e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO60172.1 - 2.4e-06 27.4 0.4 4.3e-06 26.6 0.3 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EGO60172.1 - 0.00012 21.9 0.1 0.0025 17.6 0.2 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Amidohydro_2 PF04909.14 EGO60173.1 - 2.5e-56 191.6 3.2 2.9e-56 191.4 3.2 1.0 1 0 0 1 1 1 1 Amidohydrolase UTP15_C PF09384.10 EGO60174.1 - 1.3e-48 164.4 0.0 1.9e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EGO60174.1 - 1.9e-15 57.0 10.1 0.00048 20.9 0.0 5.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO60174.1 - 1.3e-06 28.6 0.3 0.23 11.8 0.0 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 EGO60175.1 - 4.7e-63 213.0 0.0 2.6e-62 210.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO60175.1 - 6.9e-28 97.6 0.0 2.7e-27 95.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGO60175.1 - 0.021 13.8 0.0 0.036 13.0 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EGO60175.1 - 0.041 13.2 0.1 0.079 12.3 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGO60175.1 - 0.068 13.1 0.1 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family LMWPc PF01451.21 EGO60176.1 - 2.2e-42 144.8 0.0 2.5e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SIS PF01380.22 EGO60177.1 - 5.9e-11 42.3 0.0 1.3e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 SIS domain DUF2373 PF10180.9 EGO60178.1 - 8.9e-26 89.5 0.8 2.3e-25 88.2 0.8 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) SWI-SNF_Ssr4 PF08549.10 EGO60178.1 - 0.19 10.3 47.8 0.0051 15.5 26.1 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Proteasome PF00227.26 EGO60179.1 - 3.7e-47 160.3 0.0 5.3e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGO60179.1 - 2.1e-13 49.6 0.3 2.1e-13 49.6 0.3 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature IF-2B PF01008.17 EGO60179.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family YnfE PF17452.2 EGO60179.1 - 0.13 12.5 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized YnfE-like TMEM234 PF10639.9 EGO60181.1 - 3.5e-34 117.3 0.5 5.8e-33 113.4 0.5 2.0 1 1 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 EGO60181.1 - 4.1e-05 23.8 6.7 0.0005 20.2 6.7 2.0 1 1 0 1 1 1 1 EamA-like transporter family DUF1211 PF06736.11 EGO60181.1 - 0.017 15.6 0.0 0.16 12.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) RR_TM4-6 PF06459.12 EGO60183.1 - 0.16 11.8 10.4 0.24 11.2 10.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rgp1 PF08737.10 EGO60183.1 - 0.31 10.2 4.0 0.38 9.9 4.0 1.1 1 0 0 1 1 1 0 Rgp1 Dapper PF15268.6 EGO60183.1 - 0.49 9.2 14.6 0.37 9.6 12.6 1.5 1 1 0 2 2 2 0 Dapper Nop53 PF07767.11 EGO60183.1 - 2 7.7 26.1 3.1 7.1 26.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4407 PF14362.6 EGO60183.1 - 3.3 7.0 9.3 4.1 6.7 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mit_KHE1 PF10173.9 EGO60183.1 - 6 6.9 6.3 9.4 6.3 6.3 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related FUSC PF04632.12 EGO60183.1 - 7.1 5.0 7.0 8.6 4.8 7.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family RrnaAD PF00398.20 EGO60184.1 - 1.3e-54 185.1 0.0 1.7e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EGO60184.1 - 1e-05 26.2 0.0 2.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EGO60184.1 - 0.00022 21.0 0.2 0.00071 19.4 0.0 1.8 2 0 0 2 2 2 1 Met-10+ like-protein CMAS PF02353.20 EGO60184.1 - 0.00091 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EGO60184.1 - 0.0032 18.1 0.0 0.008 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGO60184.1 - 0.028 14.2 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Nop53 PF07767.11 EGO60184.1 - 0.072 12.5 4.1 0.1 12.0 4.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CENP-B_dimeris PF09026.10 EGO60184.1 - 0.1 13.0 8.0 0.22 11.9 8.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Methyltransf_18 PF12847.7 EGO60184.1 - 0.14 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NOA36 PF06524.12 EGO60184.1 - 0.25 10.6 10.0 0.39 10.0 10.0 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EGO60184.1 - 0.32 9.0 14.5 0.43 8.6 14.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 EGO60184.1 - 0.45 9.7 4.2 0.6 9.3 4.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 EGO60184.1 - 0.68 8.2 6.1 0.87 7.8 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 EGO60184.1 - 0.92 9.9 6.7 2.1 8.8 6.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Imm5 PF14423.6 EGO60184.1 - 1.4 9.1 5.2 2.7 8.2 5.2 1.4 1 0 0 1 1 1 0 Immunity protein Imm5 Arrestin_N PF00339.29 EGO60185.1 - 5.2e-15 55.8 0.0 1.7e-08 34.6 0.0 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 EGO60185.1 - 0.014 14.8 0.1 0.07 12.5 0.0 1.9 2 0 0 2 2 2 0 Bul1 C terminus DUF2076 PF09849.9 EGO60185.1 - 2.4 8.1 10.2 0.21 11.6 5.6 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Vac17 PF17321.2 EGO60186.1 - 0.0012 18.4 5.9 0.0014 18.2 5.9 1.0 1 0 0 1 1 1 1 Vacuole-related protein 17 NOA36 PF06524.12 EGO60186.1 - 0.0019 17.6 9.7 0.0024 17.3 9.7 1.0 1 0 0 1 1 1 1 NOA36 protein DUF2448 PF10476.9 EGO60186.1 - 0.025 14.5 2.5 1.6 8.6 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function C-terminus (DUF2448) DUF1754 PF08555.10 EGO60186.1 - 0.77 10.6 12.3 1.5 9.7 12.3 1.6 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) ImmE5 PF11480.8 EGO60186.1 - 0.8 10.2 9.5 4.3 7.9 3.5 2.2 2 0 0 2 2 2 0 Colicin-E5 Imm protein CENP-B_dimeris PF09026.10 EGO60186.1 - 1 9.8 6.4 1 9.8 3.1 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SURF2 PF05477.11 EGO60186.1 - 2 8.0 7.7 2.4 7.8 7.7 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Mitoc_L55 PF09776.9 EGO60186.1 - 7.3 6.4 6.4 19 5.0 2.5 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 5_nucleotid PF05761.14 EGO60187.1 - 1.7 7.5 9.2 3.5 6.4 9.2 1.6 1 0 0 1 1 1 0 5' nucleotidase family Fib_alpha PF08702.10 EGO60187.1 - 2.3 8.4 23.2 0.26 11.5 9.4 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 EGO60187.1 - 6.7 4.5 17.0 4.8 5.0 0.2 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF1515 PF07439.11 EGO60187.1 - 8.1 6.5 15.7 3.3 7.8 7.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Ribosomal_L7Ae PF01248.26 EGO60188.1 - 1.9e-22 78.8 0.0 2.1e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.18 EGO60189.1 - 2.5e-45 153.7 0.1 3.2e-45 153.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Scaffolding_pro PF11418.8 EGO60190.1 - 0.3 11.6 1.8 0.34 11.5 0.1 1.9 2 0 0 2 2 2 0 Phi29 scaffolding protein Trimer_CC PF08954.11 EGO60191.1 - 0.097 12.3 1.4 0.29 10.7 0.1 2.5 2 0 0 2 2 2 0 Trimerisation motif Ribosomal_60s PF00428.19 EGO60192.1 - 3.2e-27 95.0 13.9 3.9e-27 94.7 13.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Phage_holin_6_1 PF09682.10 EGO60192.1 - 0.44 11.0 4.3 3.2 8.2 0.6 2.1 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF2408 PF10303.9 EGO60193.1 - 1.2e-37 129.5 7.4 8.5e-24 84.7 0.2 4.7 2 2 2 4 4 4 3 Protein of unknown function (DUF2408) DUF2920 PF11144.8 EGO60193.1 - 0.074 12.2 0.0 29 3.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2920) Laminin_I PF06008.14 EGO60193.1 - 0.089 12.5 4.8 0.72 9.5 1.3 2.7 2 1 1 3 3 3 0 Laminin Domain I CAF20 PF17052.5 EGO60193.1 - 0.25 11.5 1.1 0.4 10.8 0.2 1.7 2 0 0 2 2 2 0 Cap associated factor STN1_2 PF09170.10 EGO60193.1 - 0.64 10.2 4.5 4.5 7.4 0.5 2.7 3 1 0 3 3 3 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Snapin_Pallidin PF14712.6 EGO60193.1 - 0.89 10.0 14.2 0.35 11.3 0.3 5.3 5 2 0 6 6 6 0 Snapin/Pallidin Spc7 PF08317.11 EGO60193.1 - 1.8 7.4 8.3 0.12 11.2 1.5 2.4 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 EGO60193.1 - 2.5 8.1 5.1 1.4 9.0 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) XhlA PF10779.9 EGO60193.1 - 9.5 6.5 9.4 1.2 9.4 0.1 3.9 4 1 1 5 5 5 0 Haemolysin XhlA DUF3824 PF12868.7 EGO60194.1 - 0.0085 16.8 8.0 0.0085 16.8 8.0 16.4 10 5 4 14 14 14 3 Domain of unknwon function (DUF3824) SfLAP PF11139.8 EGO60194.1 - 0.025 14.0 1.6 6.3 6.2 0.4 3.4 3 1 0 3 3 3 0 Sap, sulfolipid-1-addressing protein Motile_Sperm PF00635.26 EGO60195.1 - 1.8e-23 82.5 0.0 3.8e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Apolipoprotein PF01442.18 EGO60195.1 - 0.0059 16.5 6.5 0.0092 15.9 6.5 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ASH PF15780.5 EGO60195.1 - 0.043 14.0 0.0 0.095 12.9 0.0 1.6 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Lant_dehydr_C PF14028.6 EGO60195.1 - 0.051 13.1 1.2 0.072 12.6 1.2 1.1 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term Mitofilin PF09731.9 EGO60195.1 - 0.071 12.0 8.2 0.089 11.6 8.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Atg14 PF10186.9 EGO60195.1 - 0.09 11.9 0.4 0.13 11.4 0.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RepA_C PF04796.12 EGO60195.1 - 0.09 12.8 0.4 0.14 12.2 0.4 1.2 1 0 0 1 1 1 0 Plasmid encoded RepA protein ApoLp-III PF07464.11 EGO60195.1 - 0.13 12.4 7.2 0.22 11.6 7.2 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) FlxA PF14282.6 EGO60195.1 - 0.13 12.2 7.4 0.29 11.1 7.4 1.5 1 0 0 1 1 1 0 FlxA-like protein DUF883 PF05957.13 EGO60195.1 - 0.38 11.4 10.3 5.4 7.7 10.3 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.6 EGO60195.1 - 0.92 8.8 8.8 1.3 8.3 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YtxH PF12732.7 EGO60195.1 - 2.6 8.7 6.3 24 5.6 6.3 2.2 1 1 0 1 1 1 0 YtxH-like protein UBA PF00627.31 EGO60196.1 - 0.00061 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.20 EGO60196.1 - 0.0039 17.4 1.1 0.0077 16.4 0.0 2.2 3 0 0 3 3 3 1 UBX domain Draxin PF15550.6 EGO60196.1 - 0.025 14.5 15.7 0.038 13.9 15.7 1.2 1 0 0 1 1 1 0 Draxin SOBP PF15279.6 EGO60196.1 - 0.54 10.8 6.1 0.62 10.6 6.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Utp11 PF03998.13 EGO60196.1 - 0.55 10.1 31.0 0.49 10.3 29.6 1.4 1 1 0 1 1 1 0 Utp11 protein V_ATPase_I PF01496.19 EGO60196.1 - 7.8 4.3 10.0 8.6 4.1 10.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YCII PF03795.14 EGO60197.1 - 2.4e-08 34.3 0.0 2.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain BUD22 PF09073.10 EGO60198.1 - 0.00031 20.2 13.7 0.00034 20.1 13.7 1.2 1 0 0 1 1 1 1 BUD22 IF-2B PF01008.17 EGO60199.1 - 2.6e-37 128.6 0.0 4.3e-37 127.9 0.0 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF1722 PF08349.11 EGO60199.1 - 0.0074 16.6 0.0 0.14 12.5 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1722) Ribosomal_L7Ae PF01248.26 EGO60200.1 - 6.6e-16 57.8 0.6 7.4e-15 54.5 0.6 2.4 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FAM91_C PF14648.6 EGO60200.1 - 0.18 10.6 2.3 0.25 10.1 2.3 1.1 1 0 0 1 1 1 0 FAM91 C-terminus DUF4050 PF13259.6 EGO60200.1 - 0.2 12.0 4.9 0.47 10.8 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) CLN3 PF02487.17 EGO60200.1 - 2.1 7.3 3.0 3.2 6.7 3.0 1.2 1 0 0 1 1 1 0 CLN3 protein Paramyxo_ncap PF00973.19 EGO60200.1 - 2.3 7.0 6.8 3.2 6.5 6.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1761 PF08570.10 EGO60201.1 - 1.2e-25 90.2 3.7 1.3e-25 90.0 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) NIF PF03031.18 EGO60202.1 - 1.2e-55 187.6 0.0 1.6e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Calici_coat PF00915.20 EGO60202.1 - 0.039 12.9 0.0 0.069 12.0 0.0 1.4 1 0 0 1 1 1 0 Calicivirus coat protein UcrQ PF02939.16 EGO60203.1 - 6e-37 125.4 0.5 7.2e-37 125.2 0.5 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.25 EGO60204.1 - 3e-23 82.7 8.6 6.9e-23 81.6 8.6 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EGO60204.1 - 0.00065 18.9 5.3 0.00089 18.4 5.3 1.3 1 0 0 1 1 1 1 SigmaW regulon antibacterial Tom5 PF10642.9 EGO60205.1 - 1.3 9.1 3.7 1.1 9.4 0.1 2.6 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase Acetyltransf_1 PF00583.25 EGO60206.1 - 1.1e-13 51.4 0.0 1.7e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO60206.1 - 1.1e-07 31.8 0.1 1.7e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO60206.1 - 6.3e-07 29.3 0.1 1.1e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EGO60206.1 - 5.2e-06 26.8 0.0 8.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGO60206.1 - 0.0041 17.2 0.1 0.0075 16.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PAP_RNA-bind PF04926.15 EGO60206.1 - 0.015 14.9 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain adh_short_C2 PF13561.6 EGO60207.1 - 2.7e-46 158.0 0.1 6.3e-39 133.9 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO60207.1 - 7.6e-42 143.0 0.0 1e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO60207.1 - 1.3e-13 51.3 0.0 2e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO60207.1 - 3.8e-05 23.3 0.0 0.00043 19.8 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO60207.1 - 0.15 11.4 0.0 1.2 8.5 0.0 2.2 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Ribosomal_L26 PF16906.5 EGO60207.1 - 0.16 12.4 0.0 0.23 11.9 0.0 1.4 1 1 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal G-patch PF01585.23 EGO60208.1 - 4.8e-11 42.4 0.2 9.9e-11 41.4 0.2 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EGO60208.1 - 0.0093 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LapA_dom PF06305.11 EGO60209.1 - 0.097 12.5 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Androgen_recep PF02166.16 EGO60209.1 - 1.2 7.9 5.6 1.2 7.9 5.6 1.0 1 0 0 1 1 1 0 Androgen receptor Mito_carr PF00153.27 EGO60210.1 - 5.5e-64 212.1 6.7 3.1e-22 78.3 0.2 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.16 EGO60211.1 - 6.1e-45 151.3 0.4 7.1e-45 151.1 0.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Anp1 PF03452.14 EGO60212.1 - 3.5e-110 367.6 0.0 4.2e-110 367.3 0.0 1.1 1 0 0 1 1 1 1 Anp1 HhH-GPD PF00730.25 EGO60213.1 - 2.5e-14 53.6 0.0 7.7e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein TerB_C PF15615.6 EGO60213.1 - 0.99 9.7 4.6 0.5 10.6 0.4 2.2 2 0 0 2 2 2 0 TerB-C domain Ecm33 PF12454.8 EGO60215.1 - 1.4e-14 53.9 2.4 4.2e-14 52.4 2.4 1.9 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 EGO60215.1 - 1.1e-08 35.1 3.4 0.26 11.4 0.2 4.9 1 1 1 3 3 3 3 Receptor L domain LRR_5 PF13306.6 EGO60215.1 - 0.0056 16.6 2.3 0.03 14.3 0.1 2.5 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) AMP-binding PF00501.28 EGO60216.1 - 2.1e-86 290.2 0.0 2.7e-86 289.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO60216.1 - 1.3e-18 67.7 0.5 3.4e-18 66.4 0.2 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 EGO60216.1 - 0.00014 20.9 0.0 0.0015 17.5 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter R-HINP1I PF11463.8 EGO60216.1 - 0.0049 16.3 0.0 0.0078 15.7 0.0 1.3 1 0 0 1 1 1 1 R.HinP1I restriction endonuclease RTX_C PF08339.10 EGO60216.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 RTX C-terminal domain Methyltransf_23 PF13489.6 EGO60217.1 - 4.6e-11 42.8 0.0 8e-11 42.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO60217.1 - 2e-07 31.6 0.0 6.8e-07 29.9 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO60217.1 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO60217.1 - 0.00057 20.6 0.0 0.0061 17.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO60217.1 - 0.0035 18.1 0.0 0.012 16.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PTPRCAP PF15713.5 EGO60217.1 - 0.018 15.3 3.1 0.031 14.6 3.1 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated NAAA-beta PF15508.6 EGO60217.1 - 0.019 15.3 0.2 0.044 14.1 0.2 1.6 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Ubie_methyltran PF01209.18 EGO60217.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GHL13 PF14883.6 EGO60217.1 - 0.1 11.6 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 AhpC-TSA PF00578.21 EGO60218.1 - 3.7e-23 81.8 0.0 7.5e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGO60218.1 - 6.2e-17 61.7 0.2 1.3e-16 60.7 0.2 1.7 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EGO60218.1 - 0.018 15.1 0.0 0.12 12.5 0.0 2.0 1 1 1 2 2 2 0 AhpC/TSA antioxidant enzyme Yae1_N PF09811.9 EGO60220.1 - 2.5e-11 43.1 5.3 4.7e-11 42.2 5.3 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal TFIIA PF03153.13 EGO60220.1 - 0.082 12.9 10.6 0.093 12.7 10.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_31 PF13614.6 EGO60220.1 - 0.36 10.7 1.3 0.58 10.1 1.3 1.2 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 EGO60220.1 - 4.4 6.0 7.0 5 5.8 7.0 1.1 1 0 0 1 1 1 0 Presenilin DUF1180 PF06679.12 EGO60220.1 - 8.6 6.7 9.8 1.7 9.0 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) HA2 PF04408.23 EGO60221.1 - 4e-19 68.9 0.1 4e-19 68.9 0.1 3.0 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGO60221.1 - 4.9e-19 68.5 0.0 9.6e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DnaJ_C PF01556.18 EGO60222.1 - 6.3e-29 101.0 0.0 9.9e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGO60222.1 - 5e-26 90.6 3.2 1.2e-25 89.4 3.2 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGO60222.1 - 1.4e-14 54.2 16.9 2.2e-14 53.5 16.9 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGO60222.1 - 4.6e-05 23.3 6.6 0.039 13.9 0.7 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGO60222.1 - 0.001 19.0 7.8 0.16 12.0 1.4 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 EGO60222.1 - 0.74 9.5 7.0 1 9.0 1.0 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Lar_restr_allev PF14354.6 EGO60222.1 - 0.99 9.8 8.8 0.34 11.3 1.2 2.9 1 1 2 3 3 3 0 Restriction alleviation protein Lar FA_desaturase PF00487.24 EGO60223.1 - 4.1e-27 95.6 17.8 6.7e-27 94.9 17.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EGO60223.1 - 5e-19 67.5 0.3 9.5e-19 66.6 0.3 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) ATG2_CAD PF13329.6 EGO60224.1 - 3.8e-50 169.6 0.5 8.9e-50 168.4 0.5 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 EGO60224.1 - 1.4e-30 105.4 0.4 5.7e-30 103.5 0.2 2.2 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 EGO60224.1 - 1.1e-06 28.8 0.2 4.5e-06 26.8 0.1 2.1 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 EGO60224.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Amino_oxidase PF01593.24 EGO60225.1 - 5e-52 177.7 0.1 8.8e-51 173.6 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGO60225.1 - 3.7e-15 55.9 0.1 7.7e-15 54.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGO60225.1 - 9.1e-07 28.4 0.0 7.1e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO60225.1 - 2e-06 28.3 0.5 2.4e-05 24.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGO60225.1 - 3.4e-05 23.9 0.1 0.0079 16.2 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EGO60225.1 - 0.00011 22.0 1.3 0.00078 19.1 1.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGO60225.1 - 0.00054 18.8 0.1 0.15 10.7 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein AlaDh_PNT_C PF01262.21 EGO60225.1 - 0.0022 17.3 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EGO60225.1 - 0.0024 17.2 0.6 0.0036 16.6 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EGO60225.1 - 0.0097 15.0 0.3 0.021 13.9 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGO60225.1 - 0.015 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 EGO60225.1 - 0.027 13.3 0.3 0.066 12.0 0.1 1.5 1 1 0 2 2 2 0 MCRA family Prenylcys_lyase PF07156.14 EGO60225.1 - 0.029 13.5 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Prenylcysteine lyase FAD_oxidored PF12831.7 EGO60225.1 - 0.14 11.5 0.8 0.23 10.8 0.6 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Acyl-CoA_dh_1 PF00441.24 EGO60226.1 - 4.5e-36 124.3 0.4 6.5e-36 123.8 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 EGO60226.1 - 2.7e-20 72.3 0.0 7.2e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 EGO60226.1 - 3e-16 59.4 0.2 5.4e-16 58.6 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGO60226.1 - 3e-09 37.5 0.2 2.1e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGO60226.1 - 0.0021 18.3 0.0 0.0036 17.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SAE2 PF08573.10 EGO60228.1 - 1.2e-33 116.5 0.4 1e-32 113.5 0.0 2.7 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus GIT_CC PF16559.5 EGO60228.1 - 0.14 12.1 1.9 1.4 8.8 0.6 2.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4795 PF16043.5 EGO60228.1 - 0.17 11.5 5.4 1.2 8.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) FAD_SOX PF18371.1 EGO60228.1 - 0.23 11.8 0.4 0.48 10.8 0.1 1.7 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DDE_Tnp_1_2 PF13586.6 EGO60228.1 - 2 8.8 4.8 0.49 10.8 0.3 2.3 2 0 0 2 2 2 0 Transposase DDE domain UCH PF00443.29 EGO60229.1 - 1.9e-48 165.2 0.0 3e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO60229.1 - 6.6e-10 39.1 0.0 6.1e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HAD_2 PF13419.6 EGO60230.1 - 1.4e-05 25.2 0.0 2.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO60230.1 - 0.019 15.0 0.0 0.043 13.9 0.0 1.7 1 1 0 1 1 1 0 HAD-hyrolase-like Ribosomal_L5e PF17144.4 EGO60231.1 - 3.7e-82 274.1 0.3 5.4e-82 273.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EGO60231.1 - 2.8e-34 117.9 5.9 2.8e-34 117.9 5.9 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF4473 PF14747.6 EGO60231.1 - 0.95 10.1 8.9 1 10.0 1.4 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4473) LRR_4 PF12799.7 EGO60233.1 - 0.00016 22.0 2.6 1.3 9.6 0.3 5.0 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGO60233.1 - 0.00023 20.9 19.7 17 5.8 0.0 8.8 9 0 0 9 9 9 1 Leucine Rich repeat LRR_1 PF00560.33 EGO60233.1 - 0.31 11.7 0.9 2.2e+02 3.1 0.0 4.8 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 EGO60233.1 - 0.74 9.6 3.4 0.91 9.3 0.1 3.0 4 0 0 4 4 4 0 Leucine rich repeat Plasmodium_Vir PF05795.11 EGO60233.1 - 0.91 8.9 5.0 1.6 8.0 5.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein YqzE PF14038.6 EGO60233.1 - 2.4 8.2 4.4 54 3.9 3.8 2.8 2 0 0 2 2 2 0 YqzE-like protein Rtf2 PF04641.12 EGO60233.1 - 2.5 7.4 13.8 5.9 6.2 13.8 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger zf-UBR PF02207.20 EGO60234.1 - 2.7e-14 53.1 3.4 2.7e-14 53.1 3.4 2.7 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Mucin PF01456.17 EGO60234.1 - 0.019 15.0 16.8 0.061 13.3 16.8 1.9 1 0 0 1 1 1 0 Mucin-like glycoprotein MCM_bind PF09739.9 EGO60234.1 - 0.058 11.8 4.6 0.086 11.3 4.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor HDA2-3 PF11496.8 EGO60234.1 - 1.6 7.8 5.4 2.5 7.2 5.4 1.2 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 MCM PF00493.23 EGO60235.1 - 5.1e-99 329.9 0.0 9.4e-99 329.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGO60235.1 - 3e-39 133.7 0.1 6.1e-39 132.7 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EGO60235.1 - 1.6e-26 93.4 30.5 1.6e-26 93.4 30.5 2.5 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 EGO60235.1 - 4.9e-26 91.0 1.0 1.3e-25 89.6 1.0 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGO60235.1 - 2.7e-15 56.8 0.2 8.5e-15 55.2 0.1 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGO60235.1 - 1.3e-07 31.3 0.0 6.1e-06 25.8 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGO60235.1 - 3.2e-06 27.2 0.0 6.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGO60235.1 - 0.0041 17.0 0.0 0.031 14.1 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGO60235.1 - 0.0051 16.5 0.2 0.031 14.0 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn_ribbon_2 PF12674.7 EGO60235.1 - 0.21 12.3 0.5 0.64 10.7 0.5 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-TFIIB PF13453.6 EGO60235.1 - 0.39 10.1 1.9 0.87 9.0 1.9 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger Pkinase PF00069.25 EGO60236.1 - 7.3e-41 140.3 0.0 4e-39 134.6 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO60236.1 - 3e-21 75.9 0.0 7.4e-21 74.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Med1 PF10744.9 EGO60237.1 - 1.3e-111 373.6 0.0 2.1e-111 373.0 0.0 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Bacillus_HBL PF05791.11 EGO60238.1 - 0.00064 19.6 3.6 0.62 9.9 0.1 2.4 1 1 0 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) FlgN PF05130.12 EGO60238.1 - 0.00085 19.8 3.5 0.00085 19.8 3.5 2.9 2 1 1 3 3 3 1 FlgN protein DUF4763 PF15960.5 EGO60238.1 - 0.005 16.2 0.3 0.005 16.2 0.3 2.9 1 1 2 3 3 3 1 Domain of unknown function (DUF4763) RNA_pol PF00940.19 EGO60238.1 - 0.011 14.6 1.3 0.012 14.5 0.5 1.4 1 1 0 1 1 1 0 DNA-dependent RNA polymerase Imm41 PF15592.6 EGO60238.1 - 0.13 12.6 0.5 6.2 7.2 0.1 2.2 2 0 0 2 2 2 0 Immunity protein 41 Fib_alpha PF08702.10 EGO60238.1 - 2.4 8.3 10.0 2.5 8.3 1.2 3.2 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 EGO60238.1 - 3.2 7.0 22.1 0.59 9.4 13.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF2362 PF10154.9 EGO60238.1 - 6.7 5.5 12.7 12 4.7 12.8 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Amidohydro_1 PF01979.20 EGO60239.1 - 1.2e-06 28.1 0.2 2.5e-06 27.1 0.2 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 EGO60239.1 - 4.3e-05 23.4 0.0 0.00037 20.4 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase RCC_reductase PF06405.11 EGO60239.1 - 0.029 13.6 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) NAD_binding_6 PF08030.12 EGO60239.1 - 0.18 11.9 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain MFS_1 PF07690.16 EGO60240.1 - 2.1e-32 112.4 54.3 3.1e-32 111.9 54.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO60240.1 - 5.4e-09 35.4 15.1 5.4e-09 35.4 15.1 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MRC1 PF09444.10 EGO60241.1 - 8.3e-46 156.1 19.7 8.3e-46 156.1 19.7 9.0 5 3 3 8 8 8 1 MRC1-like domain SAGA-Tad1 PF12767.7 EGO60242.1 - 3.8e-66 223.2 0.0 5.2e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit GCP_C_terminal PF04130.13 EGO60243.1 - 1.2e-98 330.4 0.1 2.3e-98 329.5 0.1 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EGO60243.1 - 4e-82 276.3 0.0 6.3e-82 275.6 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DHO_dh PF01180.21 EGO60244.1 - 8.1e-19 67.9 0.0 2.9e-18 66.1 0.0 1.8 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase RNA_Me_trans PF04252.13 EGO60245.1 - 1.2e-84 282.8 0.0 1.4e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.22 EGO60246.1 - 6.5e-115 384.9 0.1 8.4e-115 384.5 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase GRA6 PF05084.13 EGO60246.1 - 0.062 13.3 2.8 0.21 11.5 1.0 2.2 1 1 1 2 2 2 0 Granule antigen protein (GRA6) CIAPIN1 PF05093.13 EGO60247.1 - 6.5e-41 138.9 3.1 9.9e-41 138.3 3.1 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EGO60247.1 - 7.3e-39 133.0 0.0 1e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Formyl_trans_N PF00551.19 EGO60249.1 - 7.7e-18 64.9 0.0 1.4e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase WD40 PF00400.32 EGO60250.1 - 1.3e-45 152.4 16.9 3.3e-07 30.9 0.4 8.5 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO60250.1 - 1.6e-10 41.2 0.1 0.0053 17.0 0.0 4.7 4 1 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO60250.1 - 1.6e-05 23.8 0.0 0.036 12.7 0.0 4.2 5 0 0 5 5 5 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EGO60250.1 - 0.067 11.7 0.0 0.5 8.9 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 EGO60250.1 - 0.074 11.8 0.0 1.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like MFS_1 PF07690.16 EGO60251.1 - 5.4e-13 48.6 15.1 5.4e-13 48.6 15.1 4.3 3 2 1 4 4 4 3 Major Facilitator Superfamily SelK_SelG PF10961.8 EGO60251.1 - 0.19 12.4 0.1 0.19 12.4 0.1 3.2 3 0 0 3 3 3 0 Selenoprotein SelK_SelG DUF3687 PF12459.8 EGO60251.1 - 1.1 8.9 6.4 1.9 8.1 0.8 3.5 3 0 0 3 3 3 0 D-Ala-teichoic acid biosynthesis protein AAA_18 PF13238.6 EGO60252.1 - 5.8e-07 30.1 0.0 1.1e-05 26.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 EGO60252.1 - 3.1e-05 23.8 0.0 6.1e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 EGO60252.1 - 0.00015 21.0 0.0 0.00027 20.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.6 EGO60252.1 - 0.00028 21.3 0.1 0.0026 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EGO60252.1 - 0.00031 20.5 0.0 0.00065 19.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGO60252.1 - 0.0018 18.5 0.1 0.0042 17.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGO60252.1 - 0.0039 16.5 0.0 0.006 15.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 EGO60252.1 - 0.0043 16.7 0.0 0.058 13.1 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase Cytidylate_kin PF02224.18 EGO60252.1 - 0.0052 16.6 0.2 0.16 11.7 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase TsaE PF02367.17 EGO60252.1 - 0.0054 16.7 0.0 0.0086 16.1 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EGO60252.1 - 0.0078 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGO60252.1 - 0.008 15.3 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_28 PF13521.6 EGO60252.1 - 0.0085 16.3 0.1 0.025 14.8 0.0 1.9 3 0 0 3 3 2 1 AAA domain 6PF2K PF01591.18 EGO60252.1 - 0.009 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_16 PF13191.6 EGO60252.1 - 0.017 15.5 0.0 0.021 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EGO60252.1 - 0.017 14.8 0.0 0.071 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 EGO60252.1 - 0.026 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase Viral_helicase1 PF01443.18 EGO60252.1 - 0.03 14.1 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.6 EGO60252.1 - 0.034 14.3 0.0 5 7.2 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family KTI12 PF08433.10 EGO60252.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.12 EGO60252.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EGO60252.1 - 0.079 13.5 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 EGO60252.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 EGO60252.1 - 0.099 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGO60252.1 - 0.12 12.4 0.1 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 EGO60252.1 - 0.15 11.7 0.3 0.59 9.7 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dak1 PF02733.17 EGO60252.1 - 0.2 10.5 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Dak1 domain SAS-6_N PF16531.5 EGO60253.1 - 0.16 12.6 0.0 0.17 12.5 0.0 1.2 1 1 0 1 1 1 0 Centriolar protein SAS N-terminal PRELI PF04707.14 EGO60254.1 - 7.3e-43 146.1 0.2 8.6e-43 145.9 0.2 1.1 1 0 0 1 1 1 1 PRELI-like family Peptidase_M24 PF00557.24 EGO60255.1 - 4e-45 154.1 0.2 5e-45 153.8 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DnaJ PF00226.31 EGO60256.1 - 9.3e-21 73.7 2.7 1.5e-20 73.0 2.7 1.4 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.22 EGO60257.1 - 1.5e-72 244.4 8.7 1.6e-72 244.2 8.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin Asn_synthase PF00733.21 EGO60258.1 - 1.8e-93 314.0 0.0 5e-90 302.7 0.0 2.1 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EGO60258.1 - 2.5e-37 127.5 0.0 3.9e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGO60258.1 - 9.1e-28 97.1 0.0 1.7e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGO60258.1 - 5.8e-07 29.2 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EGO60258.1 - 0.0007 18.8 0.0 0.0032 16.6 0.0 1.9 1 1 0 1 1 1 1 NAD synthase QueC PF06508.13 EGO60258.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC UQ_con PF00179.26 EGO60259.1 - 1.1e-50 171.0 0.1 1.2e-50 170.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO60259.1 - 6.8e-06 25.8 0.0 8.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGO60259.1 - 0.004 17.4 1.7 0.012 15.9 1.7 1.8 1 1 0 1 1 1 1 RWD domain Pex19 PF04614.12 EGO60260.1 - 4.6e-75 252.6 11.9 4.6e-75 252.6 11.9 1.6 2 0 0 2 2 2 1 Pex19 protein family GlutR_dimer PF00745.20 EGO60260.1 - 0.11 12.9 0.8 0.54 10.8 0.6 2.3 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain ApbA_C PF08546.11 EGO60260.1 - 0.12 12.5 0.1 0.93 9.7 0.0 2.3 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal GET2 PF08690.10 EGO60260.1 - 0.17 11.5 11.6 0.066 12.9 7.6 2.1 1 1 0 2 2 2 0 GET complex subunit GET2 FliE PF02049.18 EGO60260.1 - 7.2 6.8 8.6 5.4 7.2 2.8 3.2 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE SCIMP PF15050.6 EGO60261.1 - 0.0046 17.4 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 SCIMP protein Ndc1_Nup PF09531.10 EGO60261.1 - 3.4 6.3 5.5 5.6 5.5 5.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DHquinase_I PF01487.15 EGO60262.1 - 1.8e-45 156.0 0.0 2.5e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.18 EGO60263.1 - 1.5e-25 89.7 0.1 2.8e-25 88.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain COPIIcoated_ERV PF07970.12 EGO60265.1 - 4.6e-37 128.0 0.0 7.1e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGO60265.1 - 2.7e-24 85.3 0.0 4.5e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Aminotran_4 PF01063.19 EGO60266.1 - 1.5e-24 87.1 0.0 2e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Phage_attach PF05354.11 EGO60268.1 - 0.058 13.3 0.0 0.064 13.1 0.0 1.1 1 0 0 1 1 1 0 Phage Head-Tail Attachment TRAPPC9-Trs120 PF08626.11 EGO60269.1 - 0.06 10.7 0.5 0.087 10.2 0.5 1.2 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit CTP_transf_like PF01467.26 EGO60270.1 - 5.4e-23 81.8 0.0 1.3e-19 70.8 0.0 3.2 2 1 1 3 3 3 2 Cytidylyltransferase-like WD40 PF00400.32 EGO60271.1 - 1.8e-12 47.5 4.0 0.0083 17.0 0.7 5.5 5 1 0 5 5 5 4 WD domain, G-beta repeat WD40_like PF17005.5 EGO60271.1 - 0.03 13.6 0.0 0.066 12.5 0.0 1.6 1 1 0 1 1 1 0 WD40-like domain FliO PF04347.13 EGO60271.1 - 0.081 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO DUF5344 PF17279.2 EGO60274.1 - 0.075 13.6 1.5 0.36 11.4 0.1 2.7 2 2 0 2 2 2 0 Family of unknown function (DUF5344) SseC PF04888.12 EGO60274.1 - 0.22 11.1 1.1 1.1 8.8 1.1 2.0 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family DLP_helical PF18709.1 EGO60274.1 - 0.26 10.5 9.7 0.21 10.8 0.4 2.9 2 1 1 3 3 3 0 Dynamin-like helical domain RRF PF01765.19 EGO60274.1 - 0.83 9.6 13.2 1.2 9.1 0.9 3.8 3 2 1 4 4 4 0 Ribosome recycling factor DUF948 PF06103.11 EGO60274.1 - 1.1 9.6 4.3 7.7 6.8 0.2 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF5446 PF17522.2 EGO60274.1 - 7.8 6.8 12.0 19 5.5 1.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5446) WD40 PF00400.32 EGO60278.1 - 1.2e-38 130.4 13.4 1.1e-09 38.7 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO60278.1 - 7.3e-13 48.6 0.8 0.001 19.3 0.0 4.9 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO60278.1 - 1.6e-09 37.2 0.6 0.37 9.7 0.0 4.5 2 2 2 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGO60278.1 - 1.2e-05 24.2 3.8 0.19 10.3 0.1 4.6 3 1 0 4 4 4 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EGO60278.1 - 0.00037 19.5 4.1 0.00048 19.1 0.2 2.9 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 EGO60278.1 - 0.00048 18.6 0.0 0.0027 16.1 0.0 2.1 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 EGO60278.1 - 0.00065 19.6 0.2 0.066 13.1 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A HPS3_N PF14761.6 EGO60278.1 - 0.015 14.9 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Nbas_N PF15492.6 EGO60278.1 - 0.036 13.4 0.0 4.1 6.6 0.0 3.0 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Hira PF07569.11 EGO60278.1 - 0.14 11.9 0.9 6.3 6.5 0.2 2.9 1 1 1 2 2 2 0 TUP1-like enhancer of split Aconitase PF00330.20 EGO60279.1 - 6e-145 483.8 0.0 7.9e-145 483.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGO60279.1 - 1.5e-38 132.1 0.0 2.7e-38 131.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Pkinase PF00069.25 EGO60280.1 - 1.3e-12 47.6 0.0 4.8e-12 45.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO60280.1 - 1.9e-07 30.6 0.0 5.1e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT PF02985.22 EGO60280.1 - 0.0001 22.2 0.1 0.083 13.2 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 EGO60280.1 - 0.0009 19.3 0.1 0.0025 17.9 0.1 1.7 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGO60280.1 - 0.0016 18.8 0.1 0.13 12.6 0.0 3.5 2 1 2 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 EGO60280.1 - 0.0084 16.6 0.1 11 6.7 0.0 3.2 2 0 0 2 2 2 2 HEAT-like repeat Kinase-like PF14531.6 EGO60280.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF3439 PF11921.8 EGO60281.1 - 5.4 7.0 8.3 1.5 8.8 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) GHMP_kinases_N PF00288.26 EGO60282.1 - 5.3e-09 36.2 0.0 1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGO60282.1 - 1.9e-06 28.1 0.0 4.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Rad52_Rad22 PF04098.15 EGO60284.1 - 2.3e-62 209.5 0.1 3.4e-62 208.9 0.1 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF4675 PF15720.5 EGO60284.1 - 0.089 12.6 9.6 0.21 11.4 9.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4675) Cut8 PF08559.10 EGO60285.1 - 2.5e-76 256.5 0.0 3e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein RRM_1 PF00076.22 EGO60286.1 - 1.4e-18 66.5 0.0 2.8e-12 46.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO60286.1 - 0.0014 18.7 0.0 0.024 14.8 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif N_BRCA1_IG PF16158.5 EGO60287.1 - 7.1e-28 97.3 0.0 2e-27 95.9 0.0 1.9 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 EGO60287.1 - 5.5e-16 58.1 66.2 3.6e-07 29.9 9.6 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type DMPK_coil PF08826.10 EGO60287.1 - 0.54 10.4 4.3 0.48 10.6 0.1 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like Hydin_ADK PF17213.3 EGO60287.1 - 1.2 9.4 6.1 0.3 11.3 0.3 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain C1_2 PF03107.16 EGO60287.1 - 1.3 9.4 57.3 0.21 11.9 10.7 4.6 4 0 0 4 4 4 0 C1 domain UPF0052 PF01933.18 EGO60288.1 - 8.8e-36 123.6 0.0 1e-35 123.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Btz PF09405.10 EGO60290.1 - 2.4e-31 108.7 1.8 5.4e-31 107.5 1.8 1.6 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Asp PF00026.23 EGO60292.1 - 2.8e-65 220.8 0.6 3.7e-65 220.4 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGO60292.1 - 8.2e-17 62.0 1.1 2.2e-14 54.1 1.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGO60292.1 - 0.0002 21.9 0.7 0.86 10.3 0.2 3.1 2 1 0 2 2 2 2 Aspartyl protease AhpC-TSA_2 PF13911.6 EGO60293.1 - 5.3e-19 68.4 0.0 1.5e-18 67.0 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EGO60293.1 - 6.4e-05 22.9 0.0 0.00019 21.3 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGO60293.1 - 0.0099 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Redoxin SARAF PF06682.12 EGO60294.1 - 0.0028 17.4 2.4 0.26 10.9 2.1 3.3 2 1 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis HemY_N PF07219.13 EGO60294.1 - 0.14 12.4 0.5 19 5.5 0.0 3.4 4 0 0 4 4 4 0 HemY protein N-terminus Glyco_hydro_32N PF00251.20 EGO60296.1 - 1.3e-73 248.2 4.1 1.9e-73 247.7 4.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EGO60296.1 - 6.4e-23 81.5 0.1 1.1e-22 80.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 EGO60296.1 - 0.0042 17.2 0.1 0.0079 16.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) zf-MYND PF01753.18 EGO60297.1 - 2.1e-10 40.5 7.7 3.2e-10 39.9 7.7 1.3 1 0 0 1 1 1 1 MYND finger CDC48_N PF02359.18 EGO60297.1 - 0.16 12.2 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain 2OG-FeII_Oxy_3 PF13640.6 EGO60298.1 - 7e-10 39.7 0.0 1.2e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC1 PF03109.16 EGO60299.1 - 7.5e-30 103.5 0.0 1.3e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family CRISPR_Cas6 PF10040.9 EGO60299.1 - 0.056 14.1 0.1 0.13 12.9 0.1 1.6 1 0 0 1 1 1 0 CRISPR-associated endoribonuclease Cas6 IFRD PF05004.13 EGO60302.1 - 1.9e-78 263.7 8.1 2.4e-78 263.3 8.1 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 EGO60302.1 - 5.8e-05 23.5 0.3 33 5.1 0.0 4.8 5 1 1 6 6 6 3 HEAT-like repeat DnaG_DnaB_bind PF08278.11 EGO60302.1 - 0.012 16.2 2.4 0.18 12.4 0.0 2.9 2 1 1 3 3 3 0 DNA primase DnaG DnaB-binding FHA PF00498.26 EGO60304.1 - 1.1e-15 57.7 0.0 4.3e-15 55.8 0.0 2.1 2 0 0 2 2 2 1 FHA domain FHA_2 PF17913.1 EGO60304.1 - 0.0069 16.6 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGO60304.1 - 0.02 15.2 0.0 0.074 13.4 0.0 2.0 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Coiled PF05710.12 EGO60304.1 - 0.34 11.8 1.5 1 10.3 1.5 1.7 1 0 0 1 1 1 0 Coiled coil zf-CCCH_4 PF18044.1 EGO60305.1 - 4e-07 29.7 1.8 6.7e-07 29.0 1.8 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGO60305.1 - 2.8e-06 27.2 5.3 4.9e-06 26.4 5.3 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EGO60305.1 - 0.0036 17.2 2.4 0.0069 16.3 2.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EGO60305.1 - 0.004 17.8 0.4 0.004 17.8 0.4 2.7 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 EGO60305.1 - 0.0064 16.9 1.7 0.011 16.2 1.7 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EGO60305.1 - 0.0066 16.6 0.4 0.024 14.8 0.4 2.0 1 0 0 1 1 1 1 Zinc-finger containing family Sec1 PF00995.23 EGO60307.1 - 2.9e-126 423.0 0.0 3.3e-126 422.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Chitin_synth_1 PF01644.17 EGO60308.1 - 1.4e-75 252.7 0.3 2.1e-75 252.2 0.3 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EGO60308.1 - 4e-29 100.4 0.0 8.1e-29 99.4 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EGO60308.1 - 1.3e-20 73.5 9.5 4e-16 58.8 0.0 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGO60308.1 - 0.0019 18.1 9.2 0.0019 18.1 9.2 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 ATG27 PF09451.10 EGO60308.1 - 0.23 11.3 0.7 0.45 10.3 0.7 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF3602 PF12223.8 EGO60309.1 - 3.1e-21 75.8 10.1 2.7e-20 72.8 2.6 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) PNPase_C PF12111.8 EGO60309.1 - 3.7 7.0 9.2 4.4 6.8 0.1 3.4 3 0 0 3 3 3 0 Polyribonucleotide phosphorylase C terminal Actin PF00022.19 EGO60310.1 - 1.5e-127 425.6 0.0 6.1e-127 423.6 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGO60310.1 - 0.022 13.6 0.0 2.3 6.9 0.0 2.5 2 1 0 2 2 2 0 MreB/Mbl protein Aminotran_4 PF01063.19 EGO60311.1 - 5e-23 82.1 0.0 7.8e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV TPR_1 PF00515.28 EGO60312.1 - 1.5e-46 154.4 27.5 1.4e-06 27.8 0.1 11.2 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 EGO60312.1 - 1.9e-41 136.8 24.9 2.2e-05 24.2 0.1 11.4 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.6 EGO60312.1 - 1.3e-23 83.3 14.7 1.5e-07 32.0 0.1 7.7 6 2 1 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGO60312.1 - 4.1e-22 76.5 24.0 0.00041 20.3 0.1 11.0 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGO60312.1 - 5.5e-22 77.2 23.5 3e-06 26.8 0.0 8.4 7 1 2 9 9 9 5 TPR repeat TPR_17 PF13431.6 EGO60312.1 - 8.3e-20 69.7 10.8 0.0095 16.3 0.1 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGO60312.1 - 1.6e-19 70.0 27.1 6.9e-06 26.3 0.1 8.9 4 3 5 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 EGO60312.1 - 6.8e-17 61.7 20.3 7.3e-06 26.4 2.3 6.8 4 2 2 7 7 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 EGO60312.1 - 1.9e-13 50.4 11.7 4.2e-06 26.8 0.1 6.4 4 1 4 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGO60312.1 - 3.9e-11 42.8 18.2 0.0048 17.6 0.0 8.9 5 3 5 10 10 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGO60312.1 - 1.2e-10 40.6 18.0 0.26 11.4 0.1 8.6 8 1 1 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO60312.1 - 6.6e-09 35.9 15.0 0.056 13.7 0.3 5.9 3 2 4 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGO60312.1 - 8.7e-07 28.6 25.7 0.69 9.9 0.2 8.8 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EGO60312.1 - 1.4e-06 27.9 3.8 1.2e-05 24.9 3.7 2.3 1 1 0 1 1 1 1 MalT-like TPR region SHNi-TPR PF10516.9 EGO60312.1 - 3.5e-06 26.4 7.4 0.09 12.2 0.0 5.9 7 0 0 7 7 5 2 SHNi-TPR MAS20 PF02064.15 EGO60312.1 - 0.00011 22.4 11.2 0.0034 17.5 1.5 4.5 4 1 1 5 5 5 1 MAS20 protein import receptor DUF2561 PF10812.8 EGO60312.1 - 0.013 15.5 0.4 0.022 14.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) NPR3 PF03666.13 EGO60312.1 - 0.016 14.0 0.5 0.033 13.0 0.5 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AP3D1 PF06375.11 EGO60312.1 - 0.037 14.3 4.2 0.063 13.5 2.8 1.9 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 GPCR_chapero_1 PF11904.8 EGO60312.1 - 0.044 13.2 1.3 0.08 12.4 1.3 1.3 1 0 0 1 1 1 0 GPCR-chaperone preATP-grasp_3 PF18301.1 EGO60312.1 - 0.062 13.6 0.7 1.6 9.1 0.2 3.1 3 0 0 3 3 3 0 pre ATP-grasp 3 domain TPR_6 PF13174.6 EGO60312.1 - 0.063 13.9 18.6 32 5.4 0.0 9.0 9 1 0 9 9 9 0 Tetratricopeptide repeat TAF1_subA PF14929.6 EGO60312.1 - 0.075 12.4 0.9 0.2 11.0 0.9 1.8 1 1 0 1 1 1 0 TAF RNA Polymerase I subunit A Sel1 PF08238.12 EGO60312.1 - 0.22 12.2 5.7 10 7.0 0.1 4.7 4 0 0 4 4 3 0 Sel1 repeat MIT PF04212.18 EGO60312.1 - 0.32 11.1 10.0 65 3.7 0.2 6.1 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain RRP14 PF15459.6 EGO60312.1 - 0.52 11.0 6.3 1.8 9.2 6.3 2.0 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 TPR_3 PF07720.12 EGO60312.1 - 1 9.4 14.8 9.3 6.4 0.2 5.5 5 1 1 6 6 5 0 Tetratricopeptide repeat BTAD PF03704.17 EGO60312.1 - 3.8 7.9 13.4 9.2 6.7 0.4 5.2 5 1 1 6 6 6 0 Bacterial transcriptional activator domain ANAPC5 PF12862.7 EGO60312.1 - 4.3 7.5 12.2 38 4.4 0.0 5.4 3 2 4 7 7 6 0 Anaphase-promoting complex subunit 5 SNARE PF05739.19 EGO60313.1 - 2.9e-13 49.6 2.2 2.9e-13 49.6 2.2 2.5 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 EGO60313.1 - 1.3e-11 44.6 8.5 1.3e-11 44.6 8.5 2.0 2 1 0 2 2 2 1 Syntaxin ETRAMP PF09716.10 EGO60313.1 - 0.0072 16.4 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Synaptobrevin PF00957.21 EGO60313.1 - 0.02 14.7 2.7 0.05 13.4 0.5 2.4 2 0 0 2 2 2 0 Synaptobrevin Syntaxin_2 PF14523.6 EGO60313.1 - 0.033 14.6 1.3 0.033 14.6 1.3 2.6 2 1 0 2 2 2 0 Syntaxin-like protein DUF1640 PF07798.11 EGO60313.1 - 0.034 14.2 5.8 0.1 12.6 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) PBP1_TM PF14812.6 EGO60313.1 - 0.062 13.7 0.4 0.17 12.3 0.1 1.9 2 0 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CNOT11 PF10155.9 EGO60313.1 - 0.11 12.7 0.6 0.22 11.7 0.6 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 11 DUF2207 PF09972.9 EGO60313.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FliT PF05400.13 EGO60313.1 - 0.79 10.6 6.0 26 5.7 0.1 2.8 2 0 0 2 2 2 0 Flagellar protein FliT SIL1 PF16782.5 EGO60313.1 - 0.84 8.8 5.7 0.27 10.4 0.3 2.2 2 1 0 2 2 2 0 Nucleotide exchange factor SIL1 Fib_alpha PF08702.10 EGO60313.1 - 0.98 9.6 5.8 3 8.0 0.6 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family MCU PF04678.13 EGO60313.1 - 1.2 9.3 3.8 0.81 9.8 1.0 1.9 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Laminin_II PF06009.12 EGO60313.1 - 1.3 9.0 8.3 0.62 10.1 2.4 2.6 2 1 1 3 3 3 0 Laminin Domain II DUF2203 PF09969.9 EGO60313.1 - 2.9 8.6 5.0 23 5.7 0.7 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Brix PF04427.18 EGO60315.1 - 1.3e-31 110.3 0.2 1.6e-31 109.9 0.2 1.1 1 0 0 1 1 1 1 Brix domain RRM_1 PF00076.22 EGO60317.1 - 9.6e-35 118.2 0.3 6.4e-17 61.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGO60317.1 - 6.7e-11 42.2 0.3 0.00041 20.4 0.0 2.8 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EGO60317.1 - 6.4e-08 32.5 0.1 0.0036 17.3 0.1 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF4651 PF15513.6 EGO60317.1 - 0.012 15.4 0.2 3.1 7.7 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4651) RRM_3 PF08777.11 EGO60317.1 - 0.012 15.6 0.0 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM PF05172.13 EGO60317.1 - 0.022 14.7 0.1 5.5 7.0 0.0 2.2 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 EGO60317.1 - 0.041 13.5 0.4 5.4 6.8 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Phytochelatin PF05023.14 EGO60317.1 - 0.071 12.3 0.0 0.81 8.9 0.0 2.0 2 0 0 2 2 2 0 Phytochelatin synthase SHNi-TPR PF10516.9 EGO60318.1 - 2.9e-14 52.2 0.3 2.9e-14 52.2 0.3 3.0 3 0 0 3 3 3 1 SHNi-TPR TPR_3 PF07720.12 EGO60318.1 - 8.1e-08 32.1 6.9 2.3e-07 30.6 6.9 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO60318.1 - 2.4e-06 27.7 7.2 0.0002 21.6 1.8 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGO60318.1 - 0.00028 21.3 1.8 0.00028 21.3 1.8 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGO60318.1 - 0.0018 18.9 4.9 0.0018 18.9 4.9 4.1 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGO60318.1 - 0.0043 17.3 0.0 0.04 14.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGO60318.1 - 0.024 14.5 1.3 0.024 14.5 1.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGO60318.1 - 1.4 10.0 8.9 0.51 11.3 2.6 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat Peptidase_S64 PF08192.11 EGO60318.1 - 2 6.8 14.3 0.2 10.1 8.6 1.8 1 1 1 2 2 2 0 Peptidase family S64 TPR_1 PF00515.28 EGO60318.1 - 2.5 8.1 6.8 7 6.7 6.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGO60318.1 - 4.3 7.6 5.7 2.6 8.3 0.8 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Flavoprotein PF02441.19 EGO60319.1 - 2.3e-46 157.5 0.0 1.2e-45 155.1 0.0 1.8 1 1 0 1 1 1 1 Flavoprotein p450 PF00067.22 EGO60321.1 - 2.1e-41 142.2 0.3 7.8e-28 97.4 0.2 3.0 2 1 0 2 2 2 2 Cytochrome P450 Alpha_kinase PF02816.18 EGO60322.1 - 2.7e-51 174.3 0.5 4.1e-51 173.7 0.5 1.3 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 EGO60322.1 - 1.5e-13 51.3 0.1 3.6e-13 50.1 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EGO60322.1 - 0.00011 22.4 0.0 0.00022 21.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain HAP1_N PF04849.13 EGO60322.1 - 0.037 13.3 0.1 0.055 12.7 0.1 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Rho_N PF07498.12 EGO60323.1 - 0.0066 16.3 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain FadR_C PF07840.12 EGO60323.1 - 0.048 13.6 0.1 0.084 12.8 0.1 1.3 1 0 0 1 1 1 0 FadR C-terminal domain AidB_N PF18158.1 EGO60324.1 - 1.1e-15 57.9 0.0 3.1e-15 56.4 0.0 1.7 1 1 1 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 EGO60324.1 - 5.3e-12 46.2 0.0 4.1e-11 43.3 0.0 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGO60324.1 - 4.9e-07 29.9 0.2 2.3e-06 27.7 0.2 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ICL PF00463.21 EGO60325.1 - 0 1037.3 1.3 0 1037.1 1.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EGO60325.1 - 1e-11 44.8 0.0 1.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase SNF2_N PF00176.23 EGO60327.1 - 1.5e-53 181.7 0.1 2.4e-53 181.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 EGO60327.1 - 6.2e-27 93.5 1.6 6.2e-27 93.5 1.6 2.1 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 EGO60327.1 - 1e-09 38.7 0.0 4.5e-08 33.4 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO60327.1 - 3.7e-08 33.6 0.1 1.7e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 EGO60327.1 - 0.01 14.7 4.2 0.038 12.9 1.7 2.4 2 1 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 TK PF00265.18 EGO60327.1 - 0.04 13.8 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 Thymidine kinase ERCC3_RAD25_C PF16203.5 EGO60327.1 - 0.068 12.4 1.2 0.38 9.9 0.0 2.3 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase PDDEXK_7 PF04411.12 EGO60327.1 - 2.7 7.9 5.1 4.7 7.2 0.6 2.8 3 0 0 3 3 3 0 PD-(D/E)XK nuclease superfamily PhyH PF05721.13 EGO60328.1 - 4.9e-66 223.0 0.0 5.9e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MRP-L20 PF12824.7 EGO60330.1 - 7.7e-55 185.5 4.7 1e-54 185.1 4.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 COBRA PF04833.15 EGO60330.1 - 0.0059 16.5 0.6 0.18 11.7 0.1 2.1 2 0 0 2 2 2 1 COBRA-like protein HTH_32 PF13565.6 EGO60330.1 - 0.057 14.0 3.4 1.4 9.5 2.5 2.5 1 1 0 1 1 1 0 Homeodomain-like domain FYVE PF01363.21 EGO60331.1 - 0.042 14.0 8.9 0.17 12.0 8.9 2.0 1 0 0 1 1 1 0 FYVE zinc finger zf-B_box PF00643.24 EGO60331.1 - 5.5 7.2 6.3 2.1 8.6 2.5 2.2 2 0 0 2 2 2 0 B-box zinc finger Glyco_trans_2_3 PF13632.6 EGO60332.1 - 3.8e-38 131.4 5.8 3.8e-38 131.4 5.8 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGO60332.1 - 0.0031 17.3 0.0 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGO60332.1 - 0.073 12.5 0.3 0.47 9.9 0.3 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 21 Trehalase PF01204.18 EGO60333.1 - 1.6e-198 660.7 0.0 1.9e-198 660.4 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EGO60333.1 - 2.2e-17 62.4 0.5 3.7e-17 61.7 0.5 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF3405 PF11885.8 EGO60334.1 - 4.3e-221 735.0 1.5 5.9e-221 734.6 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) RTA1 PF04479.13 EGO60335.1 - 3.7e-71 239.0 10.0 5.2e-71 238.5 10.0 1.2 1 0 0 1 1 1 1 RTA1 like protein GATase_6 PF13522.6 EGO60336.1 - 1.6e-14 54.2 0.0 3.3e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EGO60336.1 - 1.2e-13 51.0 0.0 2.6e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EGO60336.1 - 1.1e-07 31.6 0.1 2e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EGO60336.1 - 3.8e-06 26.0 0.0 6.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Cyt-b5 PF00173.28 EGO60338.1 - 8e-12 45.1 0.1 9.1e-12 45.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MreB_Mbl PF06723.13 EGO60338.1 - 0.16 10.8 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 MreB/Mbl protein TPR_12 PF13424.6 EGO60339.1 - 8e-11 42.1 4.4 0.00014 22.0 0.0 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGO60339.1 - 2.1e-09 36.8 0.4 0.025 14.4 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGO60339.1 - 3.4e-08 33.0 1.0 0.0031 17.5 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGO60339.1 - 3.4e-07 29.8 2.7 0.0083 16.1 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGO60339.1 - 2.2e-06 27.4 1.9 0.0026 17.9 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGO60339.1 - 2.9e-05 23.8 6.8 4.4e-05 23.2 0.1 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGO60339.1 - 0.047 14.3 0.0 8.7 7.1 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 EGO60339.1 - 0.061 14.0 0.2 12 6.8 0.0 2.8 2 0 0 2 2 2 0 Sel1 repeat bZIP_1 PF00170.21 EGO60340.1 - 9.8e-07 28.8 8.9 9.8e-07 28.8 8.9 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EGO60340.1 - 5.4e-05 23.2 8.0 5.4e-05 23.2 8.0 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 EGO60340.1 - 0.0008 19.9 8.8 0.0008 19.9 8.8 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor SHE3 PF17078.5 EGO60340.1 - 0.0073 16.1 0.9 0.011 15.4 0.9 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 PKcGMP_CC PF16808.5 EGO60340.1 - 0.092 12.6 1.9 0.16 11.9 1.9 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase V_ATPase_I PF01496.19 EGO60340.1 - 0.43 8.5 2.1 0.52 8.2 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4597 PF15366.6 EGO60342.1 - 0.034 13.9 0.1 0.075 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) MS_channel PF00924.18 EGO60344.1 - 4.8e-20 72.0 3.2 7.6e-20 71.3 3.2 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 EGO60344.1 - 0.0012 18.2 0.1 0.0033 16.9 0.1 1.8 1 0 0 1 1 1 1 EF hand E1-E2_ATPase PF00122.20 EGO60344.1 - 0.026 14.0 1.8 3 7.3 1.2 2.5 2 0 0 2 2 2 0 E1-E2 ATPase EF-hand_6 PF13405.6 EGO60344.1 - 0.032 14.2 0.0 0.096 12.7 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 EGO60344.1 - 0.05 14.1 0.6 0.18 12.3 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair Fusion_gly PF00523.18 EGO60344.1 - 0.85 7.8 3.4 1.3 7.2 3.4 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 ODV-E18 PF10717.9 EGO60344.1 - 1.3 8.9 3.5 5.2 7.0 3.5 2.0 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF5383 PF17355.2 EGO60344.1 - 5.7 7.3 5.0 19 5.6 1.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5383) DUF3671 PF12420.8 EGO60344.1 - 9.1 6.4 10.4 0.32 11.1 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function FLILHELTA PF10306.9 EGO60345.1 - 7.6e-32 109.6 0.0 1.5e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EGO60345.1 - 0.006 17.1 0.0 0.015 15.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) Suf PF05843.14 EGO60345.1 - 0.081 12.9 1.2 0.11 12.5 1.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex26 PF07163.12 EGO60345.1 - 0.24 10.7 0.1 0.34 10.2 0.1 1.1 1 0 0 1 1 1 0 Pex26 protein Peptidase_A4 PF01828.17 EGO60346.1 - 2.5e-30 105.5 0.0 4.9e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase A4 family Glyco_hydro_31 PF01055.26 EGO60348.1 - 1.2e-140 469.6 5.3 1.9e-140 469.0 5.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EGO60348.1 - 1.6e-25 89.2 0.3 2e-23 82.5 0.2 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EGO60348.1 - 1.6e-05 25.1 2.7 3.8e-05 23.9 1.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) NDK PF00334.19 EGO60349.1 - 1.1e-54 184.1 0.0 1.3e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SPX PF03105.19 EGO60350.1 - 7.9e-85 286.1 9.9 7.9e-85 286.1 9.9 2.2 2 0 0 2 2 2 1 SPX domain EXS PF03124.14 EGO60350.1 - 3e-47 161.5 26.9 3.6e-24 85.7 8.1 2.1 1 1 1 2 2 2 2 EXS family DUF4407 PF14362.6 EGO60350.1 - 0.029 13.7 0.5 0.068 12.5 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUR PF01475.19 EGO60350.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Ferric uptake regulator family DUF883 PF05957.13 EGO60350.1 - 0.15 12.7 4.9 0.16 12.6 1.9 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) VMA21 PF09446.10 EGO60350.1 - 0.76 9.9 4.3 7.2 6.8 0.3 2.5 2 0 0 2 2 2 0 VMA21-like domain TMEM171 PF15471.6 EGO60352.1 - 0.064 12.2 0.3 0.095 11.7 0.3 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 CAF1A PF12253.8 EGO60353.1 - 3.3e-23 81.6 2.5 3.3e-23 81.6 2.5 3.1 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A LAP1C PF05609.12 EGO60353.1 - 4.2 6.4 29.5 0.1 11.7 19.1 2.3 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) DUF3759 PF12585.8 EGO60354.1 - 2.4e-36 123.6 5.7 3e-36 123.3 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Glyco_hydro_108 PF05838.12 EGO60354.1 - 0.044 14.2 0.1 0.064 13.7 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 108 DUF3824 PF12868.7 EGO60354.1 - 0.15 12.7 6.6 0.1 13.3 4.8 1.6 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) GCD14 PF08704.10 EGO60355.1 - 7e-64 215.9 0.0 2.7e-47 161.5 0.0 3.0 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit PIEZO PF15917.5 EGO60355.1 - 1.5 8.3 3.8 0.68 9.4 0.5 2.0 2 1 0 2 2 2 0 Piezo Transp_cyt_pur PF02133.15 EGO60357.1 - 1.2e-34 119.9 34.6 1.2e-33 116.6 34.6 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Peptidase_M50B PF13398.6 EGO60359.1 - 5.1e-59 199.3 17.3 7.4e-59 198.7 17.3 1.2 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 EGO60359.1 - 0.12 11.6 0.3 0.25 10.6 0.3 1.5 1 0 0 1 1 1 0 Peptidase family M50 UCR_Fe-S_N PF10399.9 EGO60359.1 - 1.5 8.2 4.0 1.6 8.1 0.1 2.8 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Peptidase_M18 PF02127.15 EGO60360.1 - 1.2e-129 432.9 0.0 1.4e-129 432.7 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) TMEM125 PF15109.6 EGO60360.1 - 0.088 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 TMEM125 protein family HET PF06985.11 EGO60361.1 - 3.9e-37 127.8 0.1 7.6e-37 126.9 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RAI1 PF08652.11 EGO60362.1 - 1.5e-28 98.8 0.0 3e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Sec8_exocyst PF04048.14 EGO60363.1 - 2e-52 176.9 0.4 4.8e-52 175.6 0.4 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EGO60363.1 - 5.1e-10 39.1 2.1 9.5e-10 38.2 2.1 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex TPR_14 PF13428.6 EGO60363.1 - 0.084 13.7 0.6 3.5 8.7 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF4220 PF13968.6 EGO60363.1 - 0.088 12.2 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Dor1 PF04124.12 EGO60363.1 - 0.11 11.2 3.5 0.21 10.2 3.5 1.4 1 0 0 1 1 1 0 Dor1-like family Vps51 PF08700.11 EGO60363.1 - 0.27 11.4 2.0 3.2 7.9 0.2 3.4 4 0 0 4 4 4 0 Vps51/Vps67 SMI1_KNR4 PF09346.10 EGO60365.1 - 5.9e-32 110.9 0.0 1.2e-31 109.8 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) UPF0220 PF05255.11 EGO60366.1 - 4.6e-68 227.9 2.8 5.2e-68 227.8 2.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) MIF4G_like PF09088.11 EGO60367.1 - 7.1e-90 299.9 0.6 1.2e-89 299.2 0.6 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EGO60367.1 - 2.6e-73 246.8 0.0 6.7e-73 245.5 0.0 1.7 2 0 0 2 2 2 1 MIF4G like Cnd1 PF12717.7 EGO60367.1 - 0.11 12.5 0.1 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 MIF4G PF02854.19 EGO60367.1 - 0.12 12.0 0.0 0.52 9.9 0.0 2.1 1 1 0 1 1 1 0 MIF4G domain DUF4850 PF16142.5 EGO60367.1 - 0.16 11.4 0.0 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4850) Pkinase PF00069.25 EGO60368.1 - 5.3e-65 219.4 0.0 6.5e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO60368.1 - 1e-25 90.5 0.0 1.4e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO60368.1 - 4.5e-07 29.5 0.0 2.2e-06 27.2 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EGO60368.1 - 0.00071 19.6 0.3 0.0054 16.7 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1229 PF06797.11 EGO60368.1 - 0.038 14.2 0.1 0.061 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) Choline_kinase PF01633.20 EGO60368.1 - 0.079 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EGO60368.1 - 0.093 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGO60368.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RRM_1 PF00076.22 EGO60371.1 - 2.3e-33 113.8 0.0 6.6e-16 57.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGO60371.1 - 0.00056 19.5 0.0 0.12 12.0 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EGO60371.1 - 0.02 15.1 0.0 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 EGO60371.1 - 0.036 14.1 0.0 2.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 Cas_Cas2CT1978 PF09707.10 EGO60371.1 - 0.051 13.6 0.0 3.1 7.9 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) OB_RNB PF08206.11 EGO60371.1 - 0.13 12.0 0.4 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_7 PF16367.5 EGO60371.1 - 0.17 12.0 0.0 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif Tom7 PF08038.12 EGO60372.1 - 6.1e-21 73.8 0.4 6.9e-21 73.6 0.4 1.0 1 0 0 1 1 1 1 TOM7 family Mito_carr PF00153.27 EGO60373.1 - 4.2e-54 180.4 1.9 1.3e-18 66.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-H2C2_2 PF13465.6 EGO60374.1 - 1.3e-15 57.0 26.0 4e-08 33.3 0.9 5.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 EGO60374.1 - 5.7e-13 48.5 32.1 0.00013 22.3 0.2 5.5 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO60374.1 - 4.5e-10 39.5 20.1 0.0024 18.6 0.2 5.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EGO60374.1 - 2.9e-05 24.3 8.8 0.11 12.7 0.9 3.4 2 1 1 3 3 3 3 Aberrant zinc-finger zf-met PF12874.7 EGO60374.1 - 0.041 14.3 0.1 0.041 14.3 0.1 4.9 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGO60374.1 - 0.067 13.5 0.0 0.067 13.5 0.0 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF3130 PF11328.8 EGO60374.1 - 0.19 12.0 0.4 0.68 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 CHORD PF04968.12 EGO60374.1 - 1.8 9.3 12.8 3.2 8.6 1.1 3.9 2 1 1 3 3 3 0 CHORD C1_4 PF07975.12 EGO60374.1 - 1.9 8.8 6.4 1.4 9.2 0.1 3.0 1 1 2 3 3 3 0 TFIIH C1-like domain Dicty_REP PF05086.12 EGO60374.1 - 1.9 6.3 6.5 2.7 5.9 6.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Urm1 PF09138.11 EGO60377.1 - 4e-33 113.7 0.0 4.6e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EGO60377.1 - 0.007 17.0 0.0 0.0093 16.6 0.0 1.3 1 1 0 1 1 1 1 ThiS family WD40 PF00400.32 EGO60378.1 - 3.4e-29 100.5 17.6 0.00062 20.5 0.0 11.1 11 0 0 11 11 11 7 WD domain, G-beta repeat Lactonase PF10282.9 EGO60378.1 - 0.00057 19.2 0.0 0.0022 17.3 0.0 1.9 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 EGO60378.1 - 0.015 15.6 3.2 4.3 7.7 0.1 5.6 8 0 0 8 8 8 0 Anaphase-promoting complex subunit 4 WD40 domain SPT_ssu-like PF11779.8 EGO60379.1 - 2.1e-20 72.0 7.6 2.9e-20 71.6 7.6 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like RF-1 PF00472.20 EGO60380.1 - 1.1e-24 86.6 1.4 1.1e-24 86.6 1.4 1.8 2 0 0 2 2 2 1 RF-1 domain TSA PF03249.13 EGO60380.1 - 0.019 13.8 2.3 0.023 13.5 2.3 1.1 1 0 0 1 1 1 0 Type specific antigen CSN5_C PF18323.1 EGO60380.1 - 4.9 8.1 8.0 0.4 11.6 2.7 1.8 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Actin PF00022.19 EGO60381.1 - 1.3e-150 501.5 0.0 5.2e-150 499.6 0.0 1.7 1 1 0 1 1 1 1 Actin Fes1 PF08609.10 EGO60382.1 - 1.7e-31 109.0 1.0 8e-31 106.8 0.1 2.5 2 2 0 2 2 2 1 Nucleotide exchange factor Fes1 Arm PF00514.23 EGO60382.1 - 3.8e-09 36.3 0.0 0.0012 18.8 0.0 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGO60382.1 - 1.1e-06 28.9 0.1 8.7e-06 26.0 0.1 2.2 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 EGO60382.1 - 0.00025 21.5 0.0 0.036 14.6 0.0 3.1 2 2 1 3 3 3 2 HEAT-like repeat HEAT PF02985.22 EGO60382.1 - 0.0003 20.8 0.1 0.16 12.3 0.0 3.3 3 0 0 3 3 3 1 HEAT repeat V-ATPase_H_C PF11698.8 EGO60382.1 - 0.0019 18.3 0.1 0.0092 16.1 0.0 2.0 1 1 1 2 2 2 1 V-ATPase subunit H Tti2 PF10521.9 EGO60382.1 - 0.12 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Tti2 family P_C PF06640.11 EGO60382.1 - 0.35 11.0 3.0 0.9 9.6 3.0 1.8 1 1 0 1 1 1 0 P protein C-terminus Herpes_BLLF1 PF05109.13 EGO60382.1 - 0.64 7.9 7.0 0.85 7.5 7.0 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Ribosomal_L5_C PF00673.21 EGO60383.1 - 5.2e-30 103.5 0.0 8.8e-30 102.7 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EGO60383.1 - 1.1e-05 25.6 0.0 2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 WSC PF01822.19 EGO60384.1 - 2.2e-79 261.7 82.1 8.3e-18 64.4 11.4 6.1 6 0 0 6 6 6 5 WSC domain PAN_4 PF14295.6 EGO60384.1 - 2.4e-06 27.4 0.3 2.4e-06 27.4 0.3 4.9 6 0 0 6 6 6 1 PAN domain DUF1573 PF07610.11 EGO60384.1 - 0.0096 15.9 0.2 5.6 7.1 0.0 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1573) PAN_1 PF00024.26 EGO60384.1 - 0.022 14.7 0.0 0.022 14.7 0.0 5.2 6 0 0 6 6 6 0 PAN domain PAN_4 PF14295.6 EGO60385.1 - 0.00078 19.3 0.4 0.029 14.3 0.1 2.6 2 0 0 2 2 2 2 PAN domain Glyco_hydro_16 PF00722.21 EGO60386.1 - 1.8e-17 63.4 0.7 3e-17 62.6 0.7 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 EGO60388.1 - 5.2e-49 166.8 4.8 5.2e-49 166.8 4.8 2.1 1 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EGO60388.1 - 0.074 12.9 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 MMR_HSR1 PF01926.23 EGO60389.1 - 9.3e-17 61.2 0.2 4.3e-15 55.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO60389.1 - 3.8e-08 33.0 0.2 1.1e-05 25.0 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGO60389.1 - 1.2e-06 28.6 0.1 0.00045 20.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 EGO60389.1 - 0.01 15.1 0.0 0.023 14.0 0.0 1.6 1 0 0 1 1 1 0 AIG1 family TRAP_alpha PF03896.16 EGO60389.1 - 0.014 14.6 2.0 0.024 13.9 2.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Dynamin_N PF00350.23 EGO60389.1 - 0.058 13.4 7.7 0.14 12.2 0.4 3.3 3 1 0 3 3 3 0 Dynamin family RNA_pol_Rpc4 PF05132.14 EGO60389.1 - 0.082 13.3 1.8 0.19 12.1 1.8 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 cobW PF02492.19 EGO60389.1 - 0.13 11.9 0.3 0.51 9.9 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain LTV PF04180.14 EGO60390.1 - 2.5e-125 419.2 13.8 2.8e-125 419.0 13.8 1.0 1 0 0 1 1 1 1 Low temperature viability protein RRM_1 PF00076.22 EGO60391.1 - 4.5e-19 68.0 0.0 6.8e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGO60391.1 - 0.0013 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3112 PF11309.8 EGO60392.1 - 0.74 9.2 0.0 0.74 9.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) ABC_membrane PF00664.23 EGO60393.1 - 4.4e-50 170.9 42.6 3.3e-33 115.5 18.4 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGO60393.1 - 6.7e-47 159.5 0.1 6.9e-27 94.6 0.1 2.9 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EGO60393.1 - 1.4e-05 25.5 0.7 0.096 13.1 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EGO60393.1 - 2.7e-05 24.2 2.2 0.043 13.9 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EGO60393.1 - 9.8e-05 22.3 0.7 0.55 10.0 0.1 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EGO60393.1 - 0.00013 21.3 0.0 0.012 14.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 EGO60393.1 - 0.00026 20.9 1.8 0.088 12.7 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 EGO60393.1 - 0.0003 20.3 3.1 2 7.8 0.8 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGO60393.1 - 0.00031 21.3 3.5 0.98 9.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EGO60393.1 - 0.0009 18.9 1.4 1.1 9.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MeaB PF03308.16 EGO60393.1 - 0.0022 17.0 1.8 1.1 8.1 0.3 2.7 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EGO60393.1 - 0.0026 17.5 3.0 0.77 9.4 0.1 2.9 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 EGO60393.1 - 0.015 15.4 3.9 0.16 12.0 0.4 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 EGO60393.1 - 0.016 15.5 2.0 11 6.3 0.3 3.3 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 EGO60393.1 - 0.02 15.1 0.2 4.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EGO60393.1 - 0.028 13.9 0.3 3.5 7.1 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGO60393.1 - 0.051 13.3 0.0 2.9 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EGO60393.1 - 0.053 13.2 0.2 7.1 6.2 0.2 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 EGO60393.1 - 0.1 12.5 0.4 1 9.2 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 EGO60393.1 - 0.11 12.5 5.4 0.6 10.2 0.9 2.7 2 0 0 2 2 2 0 Dynamin family AAA_25 PF13481.6 EGO60393.1 - 0.13 11.8 0.2 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGO60393.1 - 0.16 11.7 0.0 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein cobW PF02492.19 EGO60393.1 - 0.23 11.0 2.3 0.55 9.8 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 EGO60393.1 - 0.26 11.0 0.1 12 5.5 0.1 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_28 PF13521.6 EGO60393.1 - 0.45 10.7 0.0 0.45 10.7 0.0 2.9 4 0 0 4 4 2 0 AAA domain TrwB_AAD_bind PF10412.9 EGO60393.1 - 0.46 9.3 5.5 1.8 7.4 0.0 2.7 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Fcf1 PF04900.12 EGO60395.1 - 4.8e-34 116.7 0.8 1.5e-33 115.1 0.2 1.9 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 EGO60395.1 - 5.1e-13 49.4 0.0 9.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 PIN like domain GCV_T PF01571.21 EGO60395.1 - 0.065 12.6 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain ART PF01129.18 EGO60395.1 - 0.22 10.8 1.0 17 4.6 0.7 2.2 1 1 1 2 2 2 0 NAD:arginine ADP-ribosyltransferase NmrA PF05368.13 EGO60396.1 - 6.4e-77 258.2 0.0 7.3e-77 258.1 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO60396.1 - 7.3e-09 35.8 0.1 6.8e-08 32.6 0.1 1.9 1 1 0 1 1 1 1 NAD(P)H-binding DUF3798 PF12683.7 EGO60396.1 - 0.018 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) NDUF_B8 PF05821.11 EGO60396.1 - 0.041 13.7 0.2 0.064 13.1 0.2 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF2498 PF10692.9 EGO60396.1 - 0.085 12.7 0.0 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2498) ERG2_Sigma1R PF04622.12 EGO60397.1 - 1.3e-98 328.5 0.1 1.5e-98 328.2 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Chal_sti_synt_C PF02797.15 EGO60397.1 - 0.19 11.7 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain COX2-transmemb PF09125.10 EGO60397.1 - 0.25 11.2 2.9 0.36 10.6 0.9 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane EXOSC1 PF10447.9 EGO60398.1 - 1.2e-19 70.9 3.1 7.4e-14 52.3 0.2 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EGO60398.1 - 7.9e-12 44.8 0.0 1.6e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Sec2p PF06428.11 EGO60399.1 - 3.4e-09 36.6 11.2 3.4e-09 36.6 11.2 3.1 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p Atg14 PF10186.9 EGO60399.1 - 0.0033 16.6 30.8 0.027 13.5 6.3 2.7 2 1 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 EGO60399.1 - 0.073 11.0 15.5 0.27 9.1 7.1 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CENP-H PF05837.12 EGO60399.1 - 0.11 12.9 29.7 0.072 13.5 13.7 2.6 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Tropomyosin PF00261.20 EGO60399.1 - 0.21 10.9 26.9 0.29 10.5 0.5 2.4 2 1 0 2 2 2 0 Tropomyosin DUF4200 PF13863.6 EGO60399.1 - 0.25 11.7 29.1 2.6 8.5 1.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AATF-Che1 PF13339.6 EGO60399.1 - 0.81 10.4 19.0 0.99 10.1 7.7 2.5 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor AbiH PF14253.6 EGO60399.1 - 1.1 9.1 3.4 0.8 9.5 0.1 1.9 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH DUF4407 PF14362.6 EGO60399.1 - 1.3 8.3 20.6 1.1 8.5 3.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 EGO60399.1 - 1.8 9.0 29.2 0.34 11.3 4.2 2.9 2 1 0 2 2 2 0 Fez1 ERM PF00769.19 EGO60399.1 - 2 8.2 28.6 0.1 12.4 3.6 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Spc7 PF08317.11 EGO60399.1 - 3.2 6.5 28.7 2.8 6.7 14.1 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein CorA PF01544.18 EGO60399.1 - 3.6 6.8 13.1 2.1 7.6 3.2 2.4 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein SPATA24 PF15175.6 EGO60399.1 - 7.8 6.4 21.1 0.07 13.0 7.1 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 AAA_23 PF13476.6 EGO60399.1 - 8.4 6.8 20.5 3.8 8.0 4.2 2.3 2 0 0 2 2 2 0 AAA domain TruB_N PF01509.18 EGO60400.1 - 2e-45 154.8 0.0 5.3e-45 153.4 0.0 1.7 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EGO60400.1 - 1.6e-11 44.2 0.1 4.6e-11 42.7 0.1 1.8 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DUF2406 PF10295.9 EGO60400.1 - 0.017 15.8 0.0 0.071 13.8 0.0 2.1 1 0 0 1 1 1 0 Uncharacterised protein (DUF2406) DNMT1-RFD PF12047.8 EGO60401.1 - 0.06 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain Mso1_Sec1_bdg PF14475.6 EGO60402.1 - 1.6e-20 72.4 0.1 2.6e-20 71.7 0.1 1.3 1 0 0 1 1 1 1 Sec1-binding region of Mso1 SUIM_assoc PF16619.5 EGO60402.1 - 4.4 7.4 9.4 0.52 10.4 4.4 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_L28e PF01778.17 EGO60403.1 - 6.5e-38 130.0 1.0 6.5e-38 130.0 1.0 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EGO60403.1 - 4.6e-30 104.2 14.8 4.6e-30 104.2 14.8 2.7 2 1 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EGO60403.1 - 5.4e-07 29.3 21.3 7.2e-07 28.9 21.3 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 EGO60403.1 - 0.21 11.3 6.9 0.22 11.3 5.6 1.8 1 1 0 1 1 1 0 Conserved carboxylase domain MnmE_helical PF12631.7 EGO60404.1 - 1.2e-32 113.7 0.2 1.7e-32 113.3 0.2 1.2 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EGO60404.1 - 8.2e-24 84.2 0.0 1.6e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EGO60404.1 - 3.9e-19 68.8 0.0 7.2e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO60404.1 - 1.3e-05 24.8 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGO60404.1 - 0.00018 21.6 0.0 0.00036 20.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 EGO60404.1 - 0.0054 17.2 0.0 0.066 13.7 0.0 2.6 3 0 0 3 3 3 1 ABC transporter AAA_18 PF13238.6 EGO60404.1 - 0.021 15.3 0.0 3.4 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGO60404.1 - 0.022 14.7 0.1 0.073 13.0 0.0 1.9 3 0 0 3 3 3 0 RsgA GTPase AAA_24 PF13479.6 EGO60404.1 - 0.038 13.7 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PEPcase PF00311.17 EGO60404.1 - 0.11 10.5 0.0 0.17 9.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase RlmM_FDX PF18125.1 EGO60405.1 - 0.047 14.2 0.1 4.4 7.9 0.0 2.0 1 1 1 2 2 2 0 RlmM ferredoxin-like domain Metallophos PF00149.28 EGO60406.1 - 3.3e-11 44.1 0.1 3.8e-10 40.6 0.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGO60406.1 - 4.8e-05 23.6 0.9 0.0039 17.4 0.0 2.7 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain CBP_GIL PF10995.8 EGO60407.1 - 0.16 10.6 0.0 0.17 10.5 0.0 1.0 1 0 0 1 1 1 0 Cellulose biosynthesis GIL DnaJ PF00226.31 EGO60409.1 - 1.2e-19 70.2 0.8 2.9e-19 69.0 0.8 1.7 1 0 0 1 1 1 1 DnaJ domain MBOAT PF03062.19 EGO60410.1 - 3.6e-41 141.7 6.7 1.6e-40 139.5 3.5 2.2 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Pex14_N PF04695.13 EGO60410.1 - 0.033 14.8 0.1 0.66 10.6 0.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.25 EGO60411.1 - 1.6e-44 152.3 0.0 1.3e-43 149.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO60411.1 - 2.3e-27 95.9 0.0 4e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGO60411.1 - 0.01 15.2 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGO60411.1 - 0.014 14.2 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EGO60411.1 - 0.21 10.5 1.0 0.41 9.5 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain HSP90 PF00183.18 EGO60412.1 - 4.6e-224 745.1 29.6 5.9e-224 744.7 29.6 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EGO60412.1 - 2.5e-16 60.2 0.0 4.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGO60412.1 - 4.2e-10 39.6 0.1 4.2e-10 39.6 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 EGO60412.1 - 0.023 14.7 0.3 0.088 12.8 0.3 2.0 1 0 0 1 1 1 0 Tumour suppressor protein DUF1676 PF07898.13 EGO60412.1 - 0.068 13.2 3.6 0.58 10.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Peptidase_S10 PF00450.22 EGO60412.1 - 1 8.7 3.8 2.3 7.5 0.0 2.5 3 0 0 3 3 3 0 Serine carboxypeptidase Cofac_haem_bdg PF04187.13 EGO60412.1 - 5.9 6.8 6.0 1.8 8.5 0.4 2.8 2 2 1 3 3 3 0 Haem-binding uptake, Tiki superfamily, ChaN FKBP_C PF00254.28 EGO60414.1 - 5.4e-34 116.4 0.0 7.9e-34 115.9 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Flavin_Reduct PF01613.18 EGO60415.1 - 6.5e-27 94.5 0.0 1e-26 93.8 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain Ribosomal_L31 PF01197.18 EGO60416.1 - 0.00039 20.6 0.0 0.00063 19.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L31 Vps5 PF09325.10 EGO60417.1 - 3.8e-89 298.3 7.8 6.8e-89 297.5 7.8 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EGO60417.1 - 6.5e-25 87.3 0.4 1.3e-24 86.4 0.1 1.7 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 EGO60417.1 - 0.00017 21.3 6.5 0.00073 19.3 2.9 2.5 1 1 1 2 2 2 1 BAR domain of APPL family BAR_2 PF10455.9 EGO60417.1 - 0.0028 16.9 2.7 0.0052 16.0 2.4 1.6 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3_WASP_bdg PF10456.9 EGO60417.1 - 0.0054 16.2 0.6 0.023 14.2 0.6 2.0 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Lipase_GDSL PF00657.22 EGO60417.1 - 0.034 14.1 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase HBM PF16591.5 EGO60417.1 - 0.18 11.2 11.7 0.8 9.1 0.2 2.4 1 1 1 2 2 2 0 Helical bimodular sensor domain DUF713 PF05218.14 EGO60417.1 - 0.24 11.1 5.4 0.18 11.5 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF713) DUF3450 PF11932.8 EGO60417.1 - 0.4 9.9 8.3 0.18 11.1 5.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) BAR PF03114.18 EGO60417.1 - 0.42 10.2 9.7 1.1 8.8 9.7 1.8 1 1 0 1 1 1 0 BAR domain PilJ PF13675.6 EGO60417.1 - 5 7.2 7.7 0.73 9.9 0.2 3.1 3 1 1 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term TFIID_NTD2 PF04494.15 EGO60418.1 - 4.1e-40 137.0 0.2 6e-40 136.5 0.2 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 EGO60418.1 - 7.8e-40 134.1 22.5 8e-07 29.7 0.2 7.1 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO60418.1 - 3.1e-13 49.8 0.1 0.038 14.3 0.0 5.5 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EGO60418.1 - 4.4e-07 29.6 0.0 8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 EGO60418.1 - 0.00013 21.9 0.0 0.014 15.3 0.0 3.3 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGO60418.1 - 0.0083 14.8 0.1 4.1 5.9 0.0 2.8 3 0 0 3 3 3 2 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 EGO60418.1 - 0.022 14.0 0.0 2.2 7.4 0.0 2.5 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nucleoporin_N PF08801.11 EGO60418.1 - 0.11 11.2 0.0 4.3 6.0 0.0 2.9 3 1 0 3 3 3 0 Nup133 N terminal like Ge1_WD40 PF16529.5 EGO60418.1 - 0.12 11.3 2.9 13 4.6 0.6 3.9 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Med11 PF10280.9 EGO60419.1 - 5.6e-53 179.1 1.7 7.1e-53 178.7 1.7 1.1 1 0 0 1 1 1 1 Mediator complex protein Peptidase_M28 PF04389.17 EGO60421.1 - 1.1e-36 126.3 0.3 1.8e-36 125.7 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGO60421.1 - 0.0015 18.3 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Transposase_21 PF02992.14 EGO60421.1 - 0.14 11.4 0.7 0.27 10.5 0.7 1.4 1 0 0 1 1 1 0 Transposase family tnp2 Herpes_capsid PF06112.11 EGO60421.1 - 3.4 7.7 8.8 6.6 6.8 8.8 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Acetyltransf_1 PF00583.25 EGO60422.1 - 2.2e-05 24.7 0.0 4.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO60422.1 - 0.00021 21.2 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO60422.1 - 0.0022 18.4 0.0 0.0044 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO60422.1 - 0.052 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein PanZ PF12568.8 EGO60422.1 - 0.2 11.4 0.1 0.41 10.4 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ CENP-I PF07778.11 EGO60423.1 - 2.1e-09 36.6 0.1 2.1e-09 36.6 0.1 1.0 1 0 0 1 1 1 1 Mis6 CENP-I PF07778.11 EGO60424.1 - 0.017 13.9 0.2 0.017 13.8 0.2 1.0 1 0 0 1 1 1 0 Mis6 G_glu_transpept PF01019.21 EGO60426.1 - 3.6e-151 504.4 0.0 4.1e-151 504.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase CMAS PF02353.20 EGO60427.1 - 2.9e-16 59.6 0.3 1.9e-14 53.6 0.2 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EGO60427.1 - 8.1e-16 58.5 0.1 4.7e-15 56.0 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO60427.1 - 1.8e-14 54.2 0.4 3.1e-12 47.0 0.4 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO60427.1 - 4.3e-14 52.6 0.2 7.2e-12 45.4 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO60427.1 - 9e-14 51.6 0.0 1.4e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO60427.1 - 2.5e-12 47.4 0.0 6.2e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO60427.1 - 4.1e-06 26.3 0.3 5.3e-05 22.7 0.3 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EGO60427.1 - 0.00033 20.3 0.1 0.018 14.7 0.2 2.6 2 1 1 3 3 3 1 Methionine biosynthesis protein MetW Methyltransf_PK PF05891.12 EGO60427.1 - 0.00066 19.3 0.3 0.0042 16.6 0.3 2.0 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MTS PF05175.14 EGO60427.1 - 0.0022 17.6 0.1 0.029 13.9 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 EGO60427.1 - 0.0036 17.1 0.0 0.0083 15.9 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EGO60427.1 - 0.0076 16.2 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGO60427.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB DOT1 PF08123.13 EGO60427.1 - 0.048 13.2 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 FtsJ PF01728.19 EGO60427.1 - 0.054 13.6 0.0 0.15 12.2 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase YqzE PF14038.6 EGO60427.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 YqzE-like protein SecE PF00584.20 EGO60429.1 - 1.4e-15 56.9 0.0 1.6e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Vps39_2 PF10367.9 EGO60431.1 - 4.8e-06 27.0 0.0 1.3e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 EGO60431.1 - 0.0064 16.4 0.1 0.055 13.3 0.0 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS DUF3455 PF11937.8 EGO60434.1 - 7.5e-50 169.4 0.2 1e-49 169.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 EGO60434.1 - 0.00062 19.9 2.1 0.00069 19.7 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2990) Adaptin_N PF01602.20 EGO60435.1 - 4.7e-146 487.4 4.2 5.8e-146 487.1 4.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EGO60435.1 - 8.1e-20 71.2 0.0 2.4e-19 69.7 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EGO60435.1 - 5e-09 36.4 7.7 2.4e-05 24.4 0.0 4.4 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGO60435.1 - 1.5e-06 28.5 2.5 0.022 15.2 0.0 4.2 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EGO60435.1 - 2.7e-05 24.1 1.3 3.1 8.3 0.0 5.0 4 0 0 4 4 4 2 HEAT repeat DUF3730 PF12530.8 EGO60435.1 - 6.8e-05 22.5 0.7 0.0031 17.1 0.4 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3730) Arm PF00514.23 EGO60435.1 - 0.055 13.5 0.1 45 4.3 0.0 4.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 EGO60435.1 - 0.08 12.7 0.4 1.2 8.9 0.0 2.9 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 EGO60435.1 - 0.083 13.4 0.7 60 4.3 0.0 4.8 4 1 1 5 5 5 0 HEAT-like repeat EF-hand_1 PF00036.32 EGO60436.1 - 1.1e-41 137.3 12.9 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGO60436.1 - 3.5e-36 123.5 5.8 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGO60436.1 - 6.8e-35 118.7 11.4 2.3e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EGO60436.1 - 2.1e-30 102.0 9.5 1.9e-09 36.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGO60436.1 - 6.5e-26 88.6 10.6 2.6e-06 26.7 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGO60436.1 - 1.5e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGO60436.1 - 3.4e-09 36.6 1.9 0.00075 19.4 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGO60436.1 - 5.6e-09 36.3 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EGO60436.1 - 9.9e-07 28.7 0.0 0.0077 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EGO60436.1 - 5.8e-06 26.3 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 EGO60436.1 - 9.1e-05 23.3 0.2 0.0022 18.8 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 EGO60436.1 - 0.00012 22.0 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 EGO60436.1 - 0.00045 20.2 1.8 0.44 10.5 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 EGO60436.1 - 0.00062 20.1 0.8 0.66 10.3 0.1 2.7 2 1 1 3 3 3 2 RNA polymerase Rpb4 DUF3349 PF11829.8 EGO60436.1 - 0.0014 19.3 0.4 3.7 8.4 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 EGO60436.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 EGO60436.1 - 0.006 15.2 0.0 0.0062 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 EGO60436.1 - 0.0091 15.9 0.9 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 EGO60436.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 EGO60436.1 - 0.023 14.9 0.0 0.18 12.1 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 EGO60436.1 - 0.036 14.5 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RuvA_C PF07499.13 EGO60436.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 EGO60436.1 - 0.061 13.4 0.3 1.2 9.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 EGO60436.1 - 0.066 12.4 0.1 1.1 8.4 0.1 2.1 1 1 1 2 2 2 0 Cache domain DUF5132 PF17195.4 EGO60436.1 - 0.15 12.2 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) RloB PF13707.6 EGO60436.1 - 0.16 12.2 1.1 0.76 9.9 0.2 2.0 1 1 1 2 2 2 0 RloB-like protein SNARE PF05739.19 EGO60437.1 - 7.8e-15 54.6 0.5 7.8e-15 54.6 0.5 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 EGO60437.1 - 0.00026 20.7 12.3 0.0038 16.9 0.6 2.3 2 0 0 2 2 2 2 Syntaxin MCPsignal PF00015.21 EGO60437.1 - 0.00072 19.4 6.2 0.22 11.3 0.5 2.9 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DNA_repr_REX1B PF14966.6 EGO60437.1 - 0.036 14.7 1.9 0.11 13.1 0.2 2.6 2 1 0 2 2 2 0 DNA repair REX1-B 7TMR-HDED PF07697.11 EGO60437.1 - 0.043 13.9 4.1 0.074 13.2 4.0 1.4 1 1 0 1 1 1 0 7TM-HD extracellular DASH_Dad4 PF08650.10 EGO60437.1 - 0.094 12.7 0.3 2.4 8.2 0.0 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad4 GCP_C_terminal PF04130.13 EGO60437.1 - 0.4 10.1 5.1 0.29 10.6 0.4 2.1 2 0 0 2 2 2 0 Gamma tubulin complex component C-terminal FeoB_associated PF12669.7 EGO60437.1 - 0.73 10.3 1.8 1.3 9.5 1.8 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein SlyX PF04102.12 EGO60437.1 - 1.7 9.3 12.2 1.7 9.3 0.4 3.8 2 2 2 4 4 4 0 SlyX AA_kinase PF00696.28 EGO60438.1 - 7.2e-40 137.1 1.2 2.1e-39 135.5 0.2 2.0 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.6 EGO60438.1 - 4.9e-13 48.7 3.1 9.6e-10 38.1 0.2 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 EGO60438.1 - 1.2e-12 47.3 1.2 8.5e-08 31.8 0.1 2.7 2 0 0 2 2 2 2 ACT domain ABC_membrane PF00664.23 EGO60439.1 - 4.6e-53 180.6 8.4 4.6e-53 180.6 8.4 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGO60439.1 - 5.6e-34 117.6 0.1 2e-33 115.8 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EGO60439.1 - 1.6e-05 24.5 0.1 0.00058 19.4 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGO60439.1 - 0.002 18.4 0.1 0.013 15.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EGO60439.1 - 0.0048 17.3 0.3 0.056 13.9 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGO60439.1 - 0.011 16.2 0.5 0.041 14.3 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain Sigma54_activ_2 PF14532.6 EGO60439.1 - 0.018 15.2 0.0 0.8 9.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGO60439.1 - 0.02 14.6 0.1 0.61 9.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 EGO60439.1 - 0.023 14.4 0.1 0.057 13.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EGO60439.1 - 0.026 14.2 0.8 0.068 12.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGO60439.1 - 0.029 14.4 0.1 0.095 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF3615 PF12274.8 EGO60439.1 - 0.031 14.8 0.0 0.071 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3615) DEAD PF00270.29 EGO60439.1 - 0.071 12.9 0.3 15 5.3 0.0 3.4 3 1 0 3 3 3 0 DEAD/DEAH box helicase SbcCD_C PF13558.6 EGO60439.1 - 0.2 11.9 1.3 2.5 8.4 1.3 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit CTD_bind PF04818.13 EGO60440.1 - 2.8e-19 69.7 0.2 8.7e-19 68.1 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CREPT PF16566.5 EGO60440.1 - 0.0016 18.6 0.1 0.0054 16.9 0.1 1.9 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour DUF1635 PF07795.11 EGO60440.1 - 0.0052 16.7 0.3 0.012 15.4 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) MCD_N PF17408.2 EGO60440.1 - 0.062 13.4 0.1 0.23 11.6 0.1 2.1 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain Med7 PF05983.11 EGO60440.1 - 0.074 13.1 0.4 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 MED7 protein Clathrin_lg_ch PF01086.17 EGO60441.1 - 1.5e-78 264.0 2.3 1.7e-78 263.9 2.3 1.0 1 0 0 1 1 1 1 Clathrin light chain Peptidase_M3 PF01432.20 EGO60441.1 - 0.044 13.0 0.9 0.056 12.7 0.9 1.1 1 0 0 1 1 1 0 Peptidase family M3 Histidinol_dh PF00815.20 EGO60441.1 - 0.27 10.2 1.6 0.4 9.6 1.6 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase rve_3 PF13683.6 EGO60441.1 - 0.28 11.0 0.9 0.7 9.7 0.9 1.7 1 1 0 1 1 1 0 Integrase core domain COX7a PF02238.15 EGO60442.1 - 1.2e-19 70.4 1.1 1.6e-19 70.1 1.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Methyltransf_11 PF08241.12 EGO60445.1 - 0.0012 19.5 0.0 0.0025 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO60445.1 - 0.0042 17.8 0.0 0.01 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Metallophos PF00149.28 EGO60446.1 - 1.4e-18 68.2 0.1 2.3e-18 67.4 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGO60446.1 - 5.6e-07 29.9 0.0 1.4e-05 25.4 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SF1-HH PF16275.5 EGO60447.1 - 2.4e-44 150.3 1.1 5.1e-44 149.2 1.1 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 EGO60447.1 - 7.6e-12 44.7 11.1 1.4e-05 24.9 0.8 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 EGO60447.1 - 2.7e-08 33.5 0.1 5.4e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 EGO60447.1 - 1e-06 28.6 6.6 0.00054 19.9 3.8 2.5 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 EGO60447.1 - 6.7e-05 22.6 6.4 0.032 14.1 0.2 2.9 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EGO60447.1 - 0.0015 18.3 5.0 0.46 10.3 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 EGO60447.1 - 0.017 15.0 0.7 0.017 15.0 0.7 2.4 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.8 EGO60447.1 - 3.1 8.2 9.0 44 4.5 5.1 3.3 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G GST_N PF02798.20 EGO60448.1 - 2.9e-15 56.3 0.0 5.5e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGO60448.1 - 7.2e-15 55.2 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGO60448.1 - 3.2e-12 46.6 0.0 5.9e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO60448.1 - 8.3e-11 42.0 0.0 1.4e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGO60448.1 - 4.4e-09 36.4 0.0 8.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO60448.1 - 3.8e-08 33.2 0.1 1.1e-07 31.7 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EGO60448.1 - 0.0011 18.8 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAD_binding_4 PF01565.23 EGO60449.1 - 6.8e-21 74.5 2.0 6.8e-21 74.5 2.0 2.4 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 EGO60449.1 - 1.5e-14 53.8 3.7 3.4e-13 49.5 1.2 2.6 2 0 0 2 2 2 2 Berberine and berberine like DUF5527 PF17665.1 EGO60451.1 - 0.14 11.7 0.1 0.31 10.6 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5527) DUF3807 PF12720.7 EGO60452.1 - 0.00038 20.8 24.4 0.00042 20.6 24.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) SpoIIP PF07454.11 EGO60452.1 - 0.00074 19.1 18.9 0.00081 18.9 18.9 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) CobT PF06213.12 EGO60452.1 - 0.0008 18.9 33.2 0.00094 18.7 33.2 1.0 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT RNA_pol_Rpc4 PF05132.14 EGO60452.1 - 0.0011 19.5 14.8 0.0013 19.2 14.8 1.1 1 0 0 1 1 1 1 RNA polymerase III RPC4 DUF913 PF06025.12 EGO60452.1 - 0.0014 17.7 10.7 0.0016 17.5 10.7 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) DDHD PF02862.17 EGO60452.1 - 0.0029 17.8 14.6 0.0036 17.5 14.6 1.2 1 0 0 1 1 1 1 DDHD domain DUF2052 PF09747.9 EGO60452.1 - 0.0064 16.6 17.5 0.007 16.5 17.5 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Pex14_N PF04695.13 EGO60452.1 - 0.0066 17.1 33.1 0.0088 16.7 33.1 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Velvet PF11754.8 EGO60452.1 - 0.008 16.2 18.1 0.0087 16.0 18.1 1.1 1 0 0 1 1 1 1 Velvet factor SRP-alpha_N PF04086.13 EGO60452.1 - 0.012 15.6 18.8 0.014 15.4 18.8 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 EGO60452.1 - 0.012 14.4 26.3 0.014 14.2 26.3 1.0 1 0 0 1 1 1 0 Presenilin EOS1 PF12326.8 EGO60452.1 - 0.021 14.8 9.1 0.027 14.4 9.1 1.4 1 0 0 1 1 1 0 N-glycosylation protein TFIIA PF03153.13 EGO60452.1 - 0.021 14.9 55.3 0.028 14.4 55.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SID-1_RNA_chan PF13965.6 EGO60452.1 - 0.028 12.9 9.4 0.029 12.8 9.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAPS PF04499.15 EGO60452.1 - 0.032 13.0 14.1 0.034 12.9 14.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 EGO60452.1 - 0.038 12.3 18.2 0.041 12.2 18.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Endostatin PF06482.11 EGO60452.1 - 0.04 13.4 18.9 0.046 13.2 18.9 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin GPCR_chapero_1 PF11904.8 EGO60452.1 - 0.045 13.2 12.1 0.049 13.1 12.1 1.0 1 0 0 1 1 1 0 GPCR-chaperone eIF-3_zeta PF05091.12 EGO60452.1 - 0.047 12.7 30.3 0.053 12.5 30.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Slu7 PF11708.8 EGO60452.1 - 0.05 13.4 21.9 0.059 13.1 21.9 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor eIF3_subunit PF08597.10 EGO60452.1 - 0.05 13.5 24.9 0.063 13.2 24.9 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Zip PF02535.22 EGO60452.1 - 0.053 12.7 6.5 0.05 12.8 6.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CPSF100_C PF13299.6 EGO60452.1 - 0.055 13.6 17.2 0.084 13.1 17.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Hydin_ADK PF17213.3 EGO60452.1 - 0.07 13.4 14.3 0.1 12.9 14.3 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain UPF0560 PF10577.9 EGO60452.1 - 0.076 11.5 30.7 0.087 11.3 30.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3295 PF11702.8 EGO60452.1 - 0.089 12.1 21.6 0.1 11.9 21.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF4569 PF15133.6 EGO60452.1 - 0.089 12.5 21.8 0.097 12.4 21.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Apt1 PF10351.9 EGO60452.1 - 0.094 11.6 15.3 0.1 11.4 15.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CAF1 PF04857.20 EGO60452.1 - 0.1 11.8 13.0 0.11 11.6 13.0 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease PAT1 PF09770.9 EGO60452.1 - 0.1 10.8 39.4 0.12 10.6 39.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_11 PF13086.6 EGO60452.1 - 0.11 12.3 22.2 0.12 12.1 22.2 1.0 1 0 0 1 1 1 0 AAA domain DUF3527 PF12043.8 EGO60452.1 - 0.11 12.0 17.7 0.13 11.8 17.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) NARP1 PF12569.8 EGO60452.1 - 0.12 11.3 19.8 0.14 11.1 19.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GREB1 PF15782.5 EGO60452.1 - 0.15 9.1 22.3 0.17 9.0 22.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RPN2_C PF18004.1 EGO60452.1 - 0.19 11.6 21.5 0.25 11.3 21.5 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Lin-8 PF03353.15 EGO60452.1 - 0.2 11.2 28.0 0.22 11.0 28.0 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mgr1 PF08602.10 EGO60452.1 - 0.2 10.4 8.8 0.23 10.3 8.8 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF4175 PF13779.6 EGO60452.1 - 0.24 9.3 61.0 0.33 8.8 61.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CLN3 PF02487.17 EGO60452.1 - 0.29 10.1 21.7 0.36 9.8 21.7 1.0 1 0 0 1 1 1 0 CLN3 protein DAG_kinase_N PF14513.6 EGO60452.1 - 0.3 11.3 21.8 0.35 11.1 21.8 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Gti1_Pac2 PF09729.9 EGO60452.1 - 0.31 11.1 21.6 0.38 10.8 21.6 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF908 PF06012.12 EGO60452.1 - 0.33 10.3 17.9 0.36 10.2 17.9 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Tim54 PF11711.8 EGO60452.1 - 0.33 9.7 21.1 0.39 9.5 21.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Bul1_N PF04425.12 EGO60452.1 - 0.35 9.6 19.2 0.4 9.4 19.2 1.0 1 0 0 1 1 1 0 Bul1 N terminus DUF4746 PF15928.5 EGO60452.1 - 0.38 10.1 16.7 0.46 9.9 16.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PPL5 PF18168.1 EGO60452.1 - 0.38 10.0 19.6 0.5 9.6 19.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 YjbH PF06082.11 EGO60452.1 - 0.42 9.4 14.6 0.45 9.3 14.6 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Afi1 PF07792.12 EGO60452.1 - 0.45 11.0 22.8 0.63 10.5 22.8 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RR_TM4-6 PF06459.12 EGO60452.1 - 0.49 10.2 26.7 0.66 9.7 26.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2828 PF11443.8 EGO60452.1 - 0.54 8.3 24.1 0.65 8.0 24.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CSG2 PF16965.5 EGO60452.1 - 0.55 9.1 14.8 0.65 8.9 14.8 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Plasmodium_Vir PF05795.11 EGO60452.1 - 0.56 9.6 11.8 0.64 9.4 11.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Hid1 PF12722.7 EGO60452.1 - 0.68 8.0 22.1 0.76 7.8 22.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PMSI1 PF15322.6 EGO60452.1 - 0.71 9.3 15.3 0.8 9.1 15.3 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF5523 PF17661.1 EGO60452.1 - 0.74 9.5 24.7 0.96 9.1 24.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Folliculin PF11704.8 EGO60452.1 - 0.75 9.7 19.4 0.98 9.3 19.4 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport BORG_CEP PF14957.6 EGO60452.1 - 0.76 10.9 16.5 0.97 10.6 16.5 1.2 1 0 0 1 1 1 0 Cdc42 effector DUF4228 PF14009.6 EGO60452.1 - 0.76 10.1 11.0 0.94 9.8 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) PepSY_TM PF03929.16 EGO60452.1 - 0.79 9.3 12.4 1.2 8.8 12.4 1.4 1 0 0 1 1 1 0 PepSY-associated TM region Neur_chan_memb PF02932.16 EGO60452.1 - 0.79 9.7 21.7 0.98 9.4 21.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MMR1 PF08505.10 EGO60452.1 - 0.8 9.9 28.2 1.3 9.3 28.2 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Hamartin PF04388.12 EGO60452.1 - 0.82 8.3 21.2 0.92 8.1 21.2 1.0 1 0 0 1 1 1 0 Hamartin protein Calici_coat_C PF08435.11 EGO60452.1 - 0.86 9.1 13.8 1 8.8 13.8 1.1 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal Peptidase_S64 PF08192.11 EGO60452.1 - 0.88 8.0 22.8 1 7.8 22.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 PTPRCAP PF15713.5 EGO60452.1 - 0.98 9.7 24.4 1.3 9.3 24.4 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated MMM1 PF10296.9 EGO60452.1 - 1 8.4 16.7 1.3 8.1 16.7 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 DUF3801 PF12687.7 EGO60452.1 - 1 9.4 25.1 1.2 9.2 25.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) CCDC53 PF10152.9 EGO60452.1 - 1.1 9.7 27.9 1.4 9.3 27.9 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Rtf2 PF04641.12 EGO60452.1 - 1.2 8.4 21.7 1.5 8.1 21.7 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2126 PF09899.9 EGO60452.1 - 1.3 7.0 19.0 1.6 6.7 19.0 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) RP-C_C PF11800.8 EGO60452.1 - 1.4 9.0 20.0 1.7 8.7 20.0 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Band_3_cyto PF07565.13 EGO60452.1 - 1.6 8.5 23.3 2 8.1 23.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S15 PF02129.18 EGO60452.1 - 1.6 8.2 19.1 2.1 7.9 19.1 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) VIR_N PF15912.5 EGO60452.1 - 1.6 8.2 13.2 1.9 8.0 13.2 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal SLC12 PF03522.15 EGO60452.1 - 1.7 7.6 28.0 2.1 7.3 28.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Connexin PF00029.19 EGO60452.1 - 1.7 8.3 20.2 2.4 7.9 20.2 1.2 1 0 0 1 1 1 0 Connexin Phage_GPO PF05929.11 EGO60452.1 - 1.8 8.1 22.7 2.2 7.8 22.7 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase NPR3 PF03666.13 EGO60452.1 - 1.8 7.2 24.7 2.2 7.0 24.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PA26 PF04636.13 EGO60452.1 - 1.9 7.3 18.0 2.2 7.1 18.0 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Membralin PF09746.9 EGO60452.1 - 2 7.4 18.0 2.4 7.1 18.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein CCSAP PF15748.5 EGO60452.1 - 2 8.5 29.0 2.4 8.3 29.0 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Paf1 PF03985.13 EGO60452.1 - 2.1 7.2 29.0 2.7 6.9 29.0 1.1 1 0 0 1 1 1 0 Paf1 Auxin_canalis PF05703.11 EGO60452.1 - 2.2 8.2 10.7 2.5 8.0 10.7 1.1 1 0 0 1 1 1 0 Auxin canalisation YABBY PF04690.13 EGO60452.1 - 2.2 8.8 19.8 2.8 8.5 19.8 1.2 1 0 0 1 1 1 0 YABBY protein Cellulose_synt PF03552.14 EGO60452.1 - 2.5 6.5 10.7 2.8 6.3 10.7 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF3391 PF11871.8 EGO60452.1 - 2.5 8.6 22.7 3.8 8.0 22.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) MCD PF05292.11 EGO60452.1 - 2.9 7.4 12.5 3.7 7.1 12.5 1.1 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain DUF4484 PF14831.6 EGO60452.1 - 2.9 7.9 18.0 4.6 7.2 18.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Paramyxo_ncap PF00973.19 EGO60452.1 - 3.5 6.4 19.9 4.2 6.2 19.9 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PDDEXK_6 PF04720.12 EGO60452.1 - 3.8 7.4 18.3 4.6 7.1 18.3 1.1 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Spore_coat_CotO PF14153.6 EGO60452.1 - 4 7.3 34.0 5.3 6.9 34.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Menin PF05053.13 EGO60452.1 - 4.1 5.6 14.7 4.7 5.5 14.7 1.1 1 0 0 1 1 1 0 Menin Sin_N PF04801.13 EGO60452.1 - 4.2 6.5 41.3 5.2 6.2 41.3 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region Peptidase_U57 PF05582.12 EGO60452.1 - 4.7 6.4 17.5 6.5 5.9 17.5 1.3 1 0 0 1 1 1 0 YabG peptidase U57 ALMT PF11744.8 EGO60452.1 - 4.7 5.9 23.8 5.7 5.6 23.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Baculo_PP31 PF05311.11 EGO60452.1 - 4.9 6.6 24.0 6.3 6.2 24.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) V_ATPase_I PF01496.19 EGO60452.1 - 5.4 4.8 30.1 6.4 4.6 30.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MDM10 PF12519.8 EGO60452.1 - 5.8 5.7 24.7 7 5.4 24.7 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 FixO PF02433.15 EGO60452.1 - 6.7 6.1 17.8 8.7 5.7 17.8 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Exonuc_VII_L PF02601.15 EGO60452.1 - 6.7 6.2 26.3 7.5 6.0 26.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit XRN_M PF17846.1 EGO60452.1 - 7 5.5 19.9 8.5 5.2 19.9 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Scs3p PF10261.9 EGO60452.1 - 7.1 6.1 9.9 9.9 5.6 9.9 1.3 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2072 PF09845.9 EGO60452.1 - 7.4 6.8 19.2 10 6.4 19.2 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein Glyco_transf_41 PF13844.6 EGO60452.1 - 8.1 4.8 14.0 9 4.6 14.0 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 41 DUF1387 PF07139.11 EGO60452.1 - 8.1 6.1 27.3 10 5.7 27.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF966 PF06136.13 EGO60452.1 - 8.3 6.0 21.0 9.8 5.8 21.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF3384 PF11864.8 EGO60453.1 - 5.2e-143 477.4 0.0 3.8e-142 474.6 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 EGO60453.1 - 1.6e-52 177.7 0.0 3.5e-52 176.6 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 EGO60453.1 - 1.8e-37 129.3 0.6 5.5e-34 117.8 0.0 2.2 2 0 0 2 2 2 2 Tuberin CAS_CSE1 PF03378.15 EGO60455.1 - 2.9e-187 622.6 0.0 5.9e-187 621.6 0.0 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 EGO60455.1 - 4.6e-155 516.0 0.4 1.2e-154 514.7 0.5 1.6 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.19 EGO60455.1 - 4.8e-15 55.2 0.0 1.3e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Aconitase_B_N PF11791.8 EGO60455.1 - 0.043 13.9 0.0 0.17 12.0 0.0 2.0 1 0 0 1 1 1 0 Aconitate B N-terminal domain Xpo1 PF08389.12 EGO60455.1 - 0.94 9.5 7.4 0.45 10.6 0.1 4.3 6 1 0 6 6 6 0 Exportin 1-like protein Alliinase_C PF04864.13 EGO60457.1 - 0.096 11.5 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Allinase WD40 PF00400.32 EGO60458.1 - 9e-14 51.7 9.8 0.011 16.6 0.1 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO60458.1 - 1.7e-10 41.0 0.4 0.12 12.7 0.1 4.6 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain CLTH PF10607.9 EGO60458.1 - 0.014 15.3 0.0 0.034 14.0 0.0 1.6 2 0 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain Dynamin_M PF01031.20 EGO60459.1 - 8e-102 340.3 0.2 1.6e-101 339.3 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EGO60459.1 - 8.5e-58 195.1 0.0 1.8e-57 194.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EGO60459.1 - 2.1e-29 101.5 7.9 2.1e-29 101.5 7.9 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGO60459.1 - 6.6e-06 26.2 0.3 8.6e-05 22.6 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2738 PF10927.8 EGO60459.1 - 0.014 14.5 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) TSP9 PF11493.8 EGO60459.1 - 0.44 11.2 1.6 7.1 7.4 0.5 2.5 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 AAA_15 PF13175.6 EGO60459.1 - 1.7 8.3 5.4 2.3 7.9 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain CoA_transf_3 PF02515.17 EGO60460.1 - 6.4e-67 226.3 0.0 7.9e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Glutaredoxin PF00462.24 EGO60462.1 - 1.6e-15 57.1 0.0 2.7e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin ABC_tran PF00005.27 EGO60463.1 - 2.1e-14 54.2 0.0 1.7e-13 51.2 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGO60463.1 - 1.9e-11 44.3 0.4 0.00016 21.6 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 EGO60463.1 - 0.00075 17.2 0.2 0.001 16.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 EGO60463.1 - 0.00088 19.0 0.1 0.002 17.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGO60463.1 - 0.0038 16.7 0.0 2.2 7.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 EGO60463.1 - 0.0073 16.7 0.0 0.035 14.5 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGO60463.1 - 0.0075 16.5 0.7 0.022 15.0 0.7 1.9 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EGO60463.1 - 0.0078 16.7 0.1 0.012 16.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGO60463.1 - 0.015 15.6 0.1 0.035 14.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGO60463.1 - 0.016 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EGO60463.1 - 0.019 14.9 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 EGO60463.1 - 0.023 14.4 0.0 0.031 14.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 EGO60463.1 - 0.028 14.8 0.5 0.076 13.4 0.5 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EGO60463.1 - 0.042 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EGO60463.1 - 0.049 13.1 0.2 0.12 11.8 0.2 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_14 PF13173.6 EGO60463.1 - 0.061 13.4 0.0 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EGO60463.1 - 0.064 12.9 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 EGO60463.1 - 0.096 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGO60463.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGO60463.1 - 0.18 11.7 0.2 0.35 10.8 0.2 1.4 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 EGO60463.1 - 0.19 12.0 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 EGO60464.1 - 3.7e-68 229.7 0.0 8e-68 228.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO60464.1 - 3.1e-48 164.3 0.0 5.1e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO60464.1 - 2.8e-05 23.1 0.0 2.8e-05 23.1 0.0 3.1 2 1 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 EGO60464.1 - 0.00011 21.6 0.0 0.0015 17.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Transglut_core PF01841.19 EGO60465.1 - 3.8e-12 46.6 0.7 9.1e-12 45.4 0.2 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.17 EGO60465.1 - 7.5e-08 31.9 0.1 1.6e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGO60465.1 - 0.00054 19.5 0.2 0.00054 19.5 0.2 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EGO60465.1 - 0.16 11.9 0.2 0.31 10.9 0.2 1.5 1 0 0 1 1 1 0 Variant SH3 domain Transthyretin PF00576.21 EGO60467.1 - 2.1e-36 125.0 0.0 3.1e-36 124.4 0.0 1.3 1 1 0 1 1 1 1 HIUase/Transthyretin family MG4 PF17789.1 EGO60467.1 - 0.12 12.5 0.0 0.23 11.7 0.0 1.5 2 0 0 2 2 2 0 Macroglobulin domain MG4 Aminotran_5 PF00266.19 EGO60468.1 - 2.4e-30 105.7 0.0 5.7e-21 74.9 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V DUF2264 PF10022.9 EGO60469.1 - 3e-131 437.7 0.1 3.7e-131 437.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) FH2 PF02181.23 EGO60470.1 - 7.7e-87 291.8 4.2 7.7e-87 291.8 4.2 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EGO60470.1 - 1.3e-66 223.8 0.1 4.4e-66 222.0 0.0 2.0 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGO60470.1 - 5.8e-53 179.4 3.2 2e-52 177.7 1.8 2.6 1 1 1 2 2 2 1 Diaphanous FH3 Domain DUF3579 PF12112.8 EGO60471.1 - 0.15 12.6 0.1 1.2 9.7 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3579) DUF131 PF01998.17 EGO60471.1 - 0.31 10.7 3.4 0.53 10.0 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF131 Pkinase PF00069.25 EGO60473.1 - 8.4e-64 215.5 0.0 9.9e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO60473.1 - 5.3e-30 104.6 0.0 7e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO60473.1 - 0.0067 15.8 0.0 0.024 14.0 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGO60473.1 - 0.012 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EGO60473.1 - 0.056 12.2 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase NADH_B2 PF14813.6 EGO60474.1 - 0.0095 15.7 0.9 0.015 15.1 0.9 1.4 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 KcnmB2_inactiv PF09303.10 EGO60474.1 - 0.017 14.9 0.2 0.017 14.9 0.2 1.9 2 0 0 2 2 2 0 KCNMB2, ball and chain domain CMAS PF02353.20 EGO60475.1 - 1.5e-37 129.4 0.2 2.2e-37 128.9 0.2 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EGO60475.1 - 5.5e-16 59.0 0.0 1.2e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO60475.1 - 6.4e-15 55.6 0.0 1.1e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO60475.1 - 1.2e-14 54.4 0.0 1.8e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO60475.1 - 2.2e-12 47.1 0.0 3.6e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO60475.1 - 9.4e-10 39.1 0.0 2.2e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO60475.1 - 3.2e-08 33.2 0.0 4.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EGO60475.1 - 2.8e-06 26.9 0.0 1.1e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase DOT1 PF08123.13 EGO60475.1 - 0.00014 21.5 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 EGO60475.1 - 0.00028 20.5 0.0 0.00071 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 EGO60475.1 - 0.0011 18.4 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 EGO60475.1 - 0.004 16.9 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 EGO60475.1 - 0.12 11.6 0.0 0.53 9.5 0.0 1.9 1 1 0 1 1 1 0 O-methyltransferase domain P5-ATPase PF12409.8 EGO60476.1 - 1.5e-42 144.7 0.3 7.4e-41 139.2 0.1 2.4 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 EGO60476.1 - 2.9e-26 92.1 0.0 9e-26 90.5 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EGO60476.1 - 1.2e-12 48.6 0.4 7.8e-05 23.0 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EGO60476.1 - 4.5e-05 23.2 6.3 0.00014 21.6 6.3 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EGO60476.1 - 0.0056 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGO60476.1 - 0.024 14.7 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) NAP PF00956.18 EGO60477.1 - 2e-100 335.4 14.3 2e-100 335.4 14.3 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Striatin PF08232.12 EGO60477.1 - 0.017 15.7 3.1 0.017 15.7 3.1 2.9 2 1 0 2 2 2 0 Striatin family Cwf_Cwc_15 PF04889.12 EGO60477.1 - 4.3 7.0 29.1 0.95 9.1 17.6 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein 2-Hacid_dh_C PF02826.19 EGO60478.1 - 1.7e-54 183.9 0.0 2.8e-54 183.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGO60478.1 - 6.3e-39 132.7 0.1 8.3e-39 132.3 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGO60478.1 - 1.6e-06 28.4 0.2 4.3e-06 27.0 0.2 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EGO60478.1 - 8.1e-05 22.7 0.1 0.00022 21.4 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 EGO60478.1 - 0.00015 21.4 0.2 0.024 14.2 0.0 2.5 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ACT PF01842.25 EGO60478.1 - 0.0038 17.0 0.1 0.013 15.3 0.1 2.0 1 0 0 1 1 1 1 ACT domain XdhC_C PF13478.6 EGO60478.1 - 0.014 15.9 0.0 0.062 13.8 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain 3HCDH_N PF02737.18 EGO60478.1 - 0.79 9.6 3.8 4.4 7.2 0.7 2.8 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Myosin_head PF00063.21 EGO60479.1 - 9.1e-259 860.3 0.0 1.4e-258 859.6 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 EGO60479.1 - 5.6e-27 94.1 2.7 2.5e-26 91.9 2.7 2.3 1 0 0 1 1 1 1 DIL domain IQ PF00612.27 EGO60479.1 - 1.2e-13 49.5 30.0 1.4e-06 27.5 0.5 7.1 7 0 0 7 7 7 3 IQ calmodulin-binding motif GAS PF13851.6 EGO60479.1 - 1.2e-06 28.0 12.3 1.2e-06 28.0 12.3 2.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Myosin_N PF02736.19 EGO60479.1 - 5.8e-06 26.0 3.6 1.5e-05 24.8 3.6 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 EGO60479.1 - 0.0092 16.3 0.0 0.041 14.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO60479.1 - 0.016 15.6 2.5 0.065 13.6 0.0 3.0 3 0 0 3 3 2 0 AAA ATPase domain ERM PF00769.19 EGO60479.1 - 0.018 14.9 29.4 0.057 13.2 29.4 1.8 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Fez1 PF06818.15 EGO60479.1 - 0.027 14.9 24.8 0.78 10.2 12.6 2.7 1 1 1 2 2 2 0 Fez1 FlaC_arch PF05377.11 EGO60479.1 - 0.046 14.1 9.4 0.082 13.3 0.1 3.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) zf-C4H2 PF10146.9 EGO60479.1 - 0.046 14.0 3.4 0.16 12.3 3.4 1.9 1 0 0 1 1 1 0 Zinc finger-containing protein TsaE PF02367.17 EGO60479.1 - 0.13 12.3 0.0 0.44 10.6 0.0 1.9 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF812 PF05667.11 EGO60479.1 - 0.19 10.6 26.5 0.3 9.9 26.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ATPase PF06745.13 EGO60479.1 - 0.6 9.4 5.4 13 5.0 0.0 2.7 2 0 0 2 2 2 0 KaiC APG6_N PF17675.1 EGO60479.1 - 0.93 10.0 32.2 0.26 11.8 24.6 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 EGO60479.1 - 1.3 8.2 29.6 0.4 10.0 15.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Cortex-I_coil PF09304.10 EGO60479.1 - 1.8 8.8 17.1 1.1 9.5 6.4 3.1 1 1 0 2 2 2 0 Cortexillin I, coiled coil FlgN PF05130.12 EGO60479.1 - 1.8 9.1 19.2 0.032 14.7 10.1 2.6 1 1 1 2 2 2 0 FlgN protein DegQ PF08181.11 EGO60479.1 - 3.4 7.8 5.3 1.2 9.2 0.1 3.0 2 0 0 2 2 1 0 DegQ (SacQ) family DHR10 PF18595.1 EGO60479.1 - 4.5 7.4 33.6 11 6.2 6.0 3.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain TolA_bind_tri PF16331.5 EGO60479.1 - 5.3 7.2 25.9 3.3 7.9 7.4 4.1 1 1 2 3 3 3 0 TolA binding protein trimerisation KASH_CCD PF14662.6 EGO60479.1 - 5.7 6.7 30.5 5.9 6.7 6.1 2.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH EMP24_GP25L PF01105.24 EGO60479.1 - 6.6 6.6 12.1 2.5 8.0 3.6 3.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD AAA_18 PF13238.6 EGO60480.1 - 1.2e-26 93.8 2.0 2.4e-26 92.8 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EGO60480.1 - 6.3e-09 36.4 0.1 4.6e-08 33.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain ADK PF00406.22 EGO60480.1 - 3.8e-06 27.1 0.1 0.0051 16.9 0.0 2.2 1 1 0 2 2 2 2 Adenylate kinase AAA PF00004.29 EGO60480.1 - 7.5e-05 23.2 0.0 0.0012 19.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGO60480.1 - 0.00051 20.3 0.0 0.0011 19.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGO60480.1 - 0.0025 18.0 0.2 0.026 14.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 EGO60480.1 - 0.0027 17.4 0.4 1.6 8.4 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase SKI PF01202.22 EGO60480.1 - 0.0076 16.4 0.9 0.047 13.8 0.9 1.9 1 1 0 1 1 1 1 Shikimate kinase NTPase_1 PF03266.15 EGO60480.1 - 0.0096 15.8 0.2 0.027 14.4 0.0 1.8 2 0 0 2 2 2 1 NTPase AAA_16 PF13191.6 EGO60480.1 - 0.013 15.9 0.1 0.021 15.2 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGO60480.1 - 0.016 15.4 0.0 0.039 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 EGO60480.1 - 0.024 14.9 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain AAA_5 PF07728.14 EGO60480.1 - 0.026 14.5 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) dNK PF01712.19 EGO60480.1 - 0.033 14.0 3.8 1.1 9.1 0.1 2.2 1 1 1 2 2 2 0 Deoxynucleoside kinase KTI12 PF08433.10 EGO60480.1 - 0.038 13.5 0.1 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 EGO60480.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 EGO60480.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EGO60480.1 - 0.44 10.2 1.8 13 5.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain Ham1p_like PF01725.16 EGO60481.1 - 8.6e-58 195.3 0.0 9.9e-58 195.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_C78 PF07910.13 EGO60482.1 - 4.4e-73 245.2 0.0 6.1e-73 244.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 GREB1 PF15782.5 EGO60482.1 - 0.034 11.3 4.3 0.044 10.9 4.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer zf-RAG1 PF10426.9 EGO60482.1 - 0.042 14.0 0.1 0.14 12.3 0.1 1.9 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain Peptidase_C39_2 PF13529.6 EGO60482.1 - 0.065 13.8 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase_C39 like family Zn_clus PF00172.18 EGO60483.1 - 8.6e-09 35.4 9.8 1.3e-08 34.8 9.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_2b PF00587.25 EGO60484.1 - 4.8e-38 130.9 0.0 7.2e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGO60484.1 - 9.8e-14 51.5 5.5 2.4e-13 50.3 5.5 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Ras PF00071.22 EGO60485.1 - 4.3e-46 156.5 0.0 4.9e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO60485.1 - 1.4e-16 60.8 0.0 1.9e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO60485.1 - 8.7e-07 28.5 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGO60485.1 - 2.7e-05 24.2 0.0 3.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO60485.1 - 0.00013 21.6 0.0 0.00087 18.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGO60485.1 - 0.00014 21.4 0.0 0.0003 20.3 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGO60485.1 - 0.0013 18.7 0.1 0.27 11.1 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGO60485.1 - 0.03 13.8 0.0 0.082 12.4 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 EGO60485.1 - 0.04 14.0 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain WAPL PF07814.13 EGO60486.1 - 4e-78 262.8 0.2 6.1e-78 262.2 0.2 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.6 EGO60487.1 - 8.4e-79 263.8 0.0 9.8e-79 263.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EGO60487.1 - 0.0003 20.3 0.0 0.00045 19.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GTP_CH_N PF12471.8 EGO60489.1 - 9.9e-91 302.7 0.0 1.4e-90 302.3 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EGO60489.1 - 1.6e-16 60.3 0.0 2.4e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Ribosomal_S3Ae PF01015.18 EGO60492.1 - 7.3e-89 296.7 1.6 8.8e-89 296.4 1.6 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EGO60492.1 - 0.032 14.8 0.1 0.13 12.8 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 EGO60492.1 - 0.053 13.5 0.4 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Ribosomal_L22 PF00237.19 EGO60492.1 - 0.057 13.7 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e TipAS PF07739.13 EGO60492.1 - 0.15 12.6 0.1 2.4 8.8 0.0 2.5 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Ras PF00071.22 EGO60493.1 - 4.6e-48 162.9 0.0 5.5e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO60493.1 - 1.1e-26 93.4 0.0 1.6e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO60493.1 - 6.6e-12 45.2 0.0 8.5e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGO60493.1 - 9.2e-06 25.7 0.0 3.6e-05 23.8 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO60493.1 - 0.00036 20.1 0.0 0.0014 18.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 EGO60493.1 - 0.0013 18.9 0.0 0.0032 17.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EGO60493.1 - 0.0014 19.0 0.0 0.0022 18.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 EGO60493.1 - 0.0022 17.4 0.0 0.0024 17.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 EGO60493.1 - 0.0073 16.0 0.0 0.3 10.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 EGO60493.1 - 0.0085 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGO60493.1 - 0.011 15.7 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EGO60493.1 - 0.015 15.0 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGO60493.1 - 0.054 13.8 0.0 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGO60493.1 - 0.054 14.0 0.1 0.12 12.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EGO60493.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGO60493.1 - 0.099 12.1 0.0 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 EGO60493.1 - 0.17 11.3 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein ATP_bind_1 PF03029.17 EGO60493.1 - 0.2 11.4 0.1 2.8 7.7 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Abhydrolase_1 PF00561.20 EGO60494.1 - 8.3e-25 87.9 0.0 6.3e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO60494.1 - 1.5e-14 55.1 0.1 1.5e-14 55.1 0.1 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO60494.1 - 6.4e-09 35.4 0.0 8.7e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGO60494.1 - 1.9e-07 31.0 0.3 0.015 15.0 0.0 2.3 1 1 1 2 2 2 2 PGAP1-like protein Esterase PF00756.20 EGO60494.1 - 4.7e-05 23.2 0.0 7.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 EGO60494.1 - 0.00014 22.1 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Acyl_transf_1 PF00698.21 EGO60494.1 - 0.0098 15.4 0.1 0.016 14.7 0.1 1.2 1 0 0 1 1 1 1 Acyl transferase domain DUF915 PF06028.11 EGO60494.1 - 0.089 12.1 0.1 2.9 7.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) UPF0227 PF05728.12 EGO60494.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) SRP_TPR_like PF17004.5 EGO60495.1 - 9.3e-23 80.5 3.7 2.6e-21 75.8 1.2 2.6 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 EGO60495.1 - 1.7e-17 63.6 13.3 1.7e-17 63.6 13.3 2.1 2 0 0 2 2 1 1 SRP72 RNA-binding domain TPR_2 PF07719.17 EGO60495.1 - 5.5e-06 26.1 25.0 0.11 12.6 0.3 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGO60495.1 - 3.7e-05 24.2 28.5 0.22 12.1 0.1 6.7 3 3 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGO60495.1 - 4.8e-05 23.6 24.5 0.29 11.4 1.0 7.0 5 2 2 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO60495.1 - 5.6e-05 23.3 9.9 0.0031 17.7 1.2 4.8 4 2 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EGO60495.1 - 0.0011 19.6 31.4 5.4 8.1 0.5 9.7 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGO60495.1 - 0.0014 19.2 35.5 0.043 14.5 3.6 7.0 7 1 0 7 7 7 3 Tetratricopeptide repeat PPR PF01535.20 EGO60495.1 - 0.009 16.2 0.2 12 6.4 0.1 4.8 6 0 0 6 6 6 1 PPR repeat TPR_7 PF13176.6 EGO60495.1 - 0.063 13.3 15.6 2.5 8.3 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat GGA_N-GAT PF18308.1 EGO60495.1 - 0.12 12.0 1.4 3.1 7.5 0.0 3.3 3 0 0 3 3 3 0 GGA N-GAT domain DUF4810 PF16068.5 EGO60495.1 - 0.35 11.4 0.1 0.35 11.4 0.1 3.3 4 0 0 4 4 2 0 Domain of unknown function (DUF4810) TPR_4 PF07721.14 EGO60495.1 - 0.8 10.5 21.0 4.7 8.1 0.1 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPT PF03151.16 EGO60496.1 - 1.4e-25 90.3 21.0 1.7e-25 90.0 21.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EGO60496.1 - 0.00028 20.2 22.9 0.0004 19.7 22.9 1.2 1 0 0 1 1 1 1 UAA transporter family DUF5558 PF17713.1 EGO60496.1 - 0.059 13.7 4.0 0.097 13.1 4.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5558) EamA PF00892.20 EGO60496.1 - 2.1 8.5 42.0 0.098 12.8 13.7 2.6 3 0 0 3 3 3 0 EamA-like transporter family DUF2722 PF10846.8 EGO60497.1 - 0.0058 15.6 5.4 0.0064 15.5 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 EGO60497.1 - 0.038 13.6 8.9 0.037 13.7 8.9 1.1 1 0 0 1 1 1 0 Spt20 family dsDNA_bind PF01984.20 EGO60497.1 - 0.19 12.0 9.5 0.35 11.2 9.5 1.5 1 1 0 1 1 1 0 Double-stranded DNA-binding domain Androgen_recep PF02166.16 EGO60497.1 - 4.4 6.0 10.2 3.9 6.2 10.2 1.1 1 0 0 1 1 1 0 Androgen receptor CcmD PF04995.14 EGO60497.1 - 4.8 7.3 6.4 55 4.0 4.4 2.3 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) CYSTM PF12734.7 EGO60497.1 - 9.1 6.7 15.7 20 5.6 15.7 1.5 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance UCH PF00443.29 EGO60498.1 - 1.4e-33 116.5 0.0 2.5e-33 115.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO60498.1 - 5.1e-09 36.2 0.1 2.4e-08 33.9 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2387 PF09526.10 EGO60498.1 - 0.11 12.7 0.5 3.5 7.8 0.0 3.0 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) Alb1 PF09135.11 EGO60499.1 - 1.1e-32 113.0 13.3 1.1e-32 113.0 13.3 1.9 2 0 0 2 2 2 1 Alb1 DUF2239 PF09998.9 EGO60499.1 - 0.015 15.1 0.6 0.015 15.1 0.6 2.4 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2239) DUF1754 PF08555.10 EGO60499.1 - 0.61 10.9 12.9 5.9 7.8 0.7 2.4 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) bZIP_1 PF00170.21 EGO60500.1 - 1.9e-10 40.7 6.1 4e-10 39.6 6.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGO60500.1 - 5.5e-09 36.0 4.5 1.2e-08 34.9 4.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EGO60500.1 - 0.029 14.9 4.2 0.062 13.8 4.2 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor Rep_fac-A_3 PF08661.11 EGO60503.1 - 6.4e-27 94.0 0.0 7e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 GATA PF00320.27 EGO60504.1 - 0.0016 18.0 5.7 0.12 12.1 1.7 2.5 2 0 0 2 2 2 2 GATA zinc finger Cnd1 PF12717.7 EGO60506.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Peptidase_M14 PF00246.24 EGO60507.1 - 1.2e-79 268.1 0.0 1.5e-79 267.8 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.20 EGO60508.1 - 3.5e-31 108.3 0.3 5.7e-31 107.6 0.3 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 EGO60508.1 - 4.6e-06 27.1 0.1 1.3e-05 25.6 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EGO60508.1 - 4.9e-06 26.9 0.0 1.4e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain COMPASS-Shg1 PF05205.12 EGO60509.1 - 5.7e-24 84.8 0.3 5.7e-24 84.8 0.3 2.0 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF998 PF06197.13 EGO60510.1 - 0.012 15.2 0.6 0.014 15.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) IF-2B PF01008.17 EGO60511.1 - 1.4e-48 165.6 0.0 3.6e-48 164.2 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family IF3_C PF00707.22 EGO60512.1 - 1.4e-06 28.2 3.1 2.5e-06 27.3 3.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 EGO60512.1 - 7.3e-05 22.5 3.0 0.00014 21.6 3.0 1.4 1 0 0 1 1 1 1 Mitochondrial translation initiation factor DUF3723 PF12520.8 EGO60512.1 - 0.11 11.1 1.5 0.16 10.7 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) Arm PF00514.23 EGO60513.1 - 8.8e-74 241.5 30.7 3.3e-13 49.2 0.2 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGO60513.1 - 1.3e-19 70.3 15.4 0.00029 21.3 0.4 8.1 6 2 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 EGO60513.1 - 3.2e-17 62.7 8.6 0.00011 22.5 0.1 7.1 5 2 2 7 7 7 6 HEAT repeats HEAT PF02985.22 EGO60513.1 - 3.7e-14 51.6 16.7 0.071 13.4 0.3 8.8 11 0 0 11 11 8 5 HEAT repeat Adaptin_N PF01602.20 EGO60513.1 - 3.1e-10 39.3 10.4 1.2e-08 34.0 3.6 3.2 2 1 0 3 3 3 2 Adaptin N terminal region KAP PF05804.12 EGO60513.1 - 8.5e-09 34.1 0.8 1.6e-08 33.2 0.8 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EGO60513.1 - 3.2e-08 33.2 2.8 0.0013 18.1 0.6 4.0 2 1 1 3 3 3 2 V-ATPase subunit H Arm_2 PF04826.13 EGO60513.1 - 1.1e-07 31.6 4.6 0.0017 17.9 1.2 3.1 1 1 1 2 2 2 2 Armadillo-like Cnd1 PF12717.7 EGO60513.1 - 2.1e-05 24.7 7.7 0.047 13.7 0.2 5.2 1 1 3 6 6 6 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 EGO60513.1 - 0.0015 18.6 3.8 10 6.3 0.1 5.2 3 1 5 8 8 8 1 V-ATPase subunit H IFRD PF05004.13 EGO60513.1 - 0.0026 16.9 3.6 1.8 7.6 0.2 3.7 2 2 1 3 3 3 2 Interferon-related developmental regulator (IFRD) HEAT_PBS PF03130.16 EGO60513.1 - 0.034 14.8 8.1 89 4.2 0.1 7.0 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 EGO60513.1 - 0.064 13.2 1.8 12 5.8 0.1 3.3 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central Vpu PF00558.19 EGO60513.1 - 0.13 12.1 0.5 0.4 10.5 0.2 2.0 2 0 0 2 2 2 0 Vpu protein Atx10homo_assoc PF09759.9 EGO60513.1 - 0.56 10.3 9.6 3.1 7.9 0.4 4.8 5 2 1 6 6 6 0 Spinocerebellar ataxia type 10 protein domain CBS PF00571.28 EGO60514.1 - 1.6e-25 89.3 9.9 9.1e-11 42.1 0.2 4.3 4 0 0 4 4 4 4 CBS domain RhoGAP PF00620.27 EGO60515.1 - 3e-11 43.4 0.0 6.6e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PGAP1 PF07819.13 EGO60516.1 - 4.4e-06 26.6 0.2 0.00015 21.6 0.2 2.3 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EGO60516.1 - 1.9e-05 24.3 0.0 4.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) UPF0227 PF05728.12 EGO60516.1 - 0.00059 19.8 0.1 0.0018 18.3 0.1 1.8 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Macoilin PF09726.9 EGO60516.1 - 0.00091 17.9 4.3 0.00091 17.9 4.3 2.1 1 1 1 2 2 2 1 Macoilin family Hydrolase_4 PF12146.8 EGO60516.1 - 0.0014 18.0 0.0 0.003 16.9 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EGO60516.1 - 0.013 15.7 0.0 0.013 15.7 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain SprA-related PF12118.8 EGO60516.1 - 0.027 13.6 8.2 0.068 12.3 8.2 1.7 1 0 0 1 1 1 0 SprA-related family Abhydrolase_1 PF00561.20 EGO60516.1 - 0.03 14.0 0.0 0.071 12.7 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO60516.1 - 0.1 13.2 15.4 0.069 13.7 11.4 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family Pirin_C_2 PF17954.1 EGO60517.1 - 0.041 14.1 0.3 0.089 13.0 0.3 1.5 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain Adeno_E3_CR2 PF02439.15 EGO60517.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Presenilin PF01080.17 EGO60517.1 - 7.5 5.2 5.2 12 4.6 5.2 1.2 1 0 0 1 1 1 0 Presenilin Fungal_trans PF04082.18 EGO60518.1 - 2.4e-25 89.1 0.0 5.3e-25 88.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO60518.1 - 1.3e-10 41.2 11.3 2.2e-10 40.5 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Folliculin PF11704.8 EGO60518.1 - 0.16 11.8 2.3 0.34 10.8 0.1 2.4 3 0 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport SPX PF03105.19 EGO60518.1 - 2.8 7.7 8.9 5.9 6.7 1.1 2.1 2 0 0 2 2 2 0 SPX domain Peptidase_M41 PF01434.18 EGO60519.1 - 1.7e-68 230.2 0.0 2.7e-68 229.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGO60519.1 - 2e-43 148.0 0.1 1.1e-42 145.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO60519.1 - 7.6e-12 44.9 0.2 1.9e-11 43.6 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EGO60519.1 - 3.4e-08 33.8 0.2 2.3e-07 31.2 0.0 2.4 2 1 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 EGO60519.1 - 0.0031 17.5 0.0 0.012 15.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO60519.1 - 0.0058 17.0 0.2 0.26 11.7 0.2 2.9 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGO60519.1 - 0.0093 16.2 0.0 0.85 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EGO60519.1 - 0.012 15.4 0.0 0.035 13.9 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGO60519.1 - 0.015 14.6 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_2 PF07724.14 EGO60519.1 - 0.028 14.5 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EGO60519.1 - 0.028 14.1 0.0 0.077 12.7 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EGO60519.1 - 0.11 12.1 0.4 3.5 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF4175 PF13779.6 EGO60519.1 - 0.26 9.2 8.3 0.39 8.6 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) HCO3_cotransp PF00955.21 EGO60520.1 - 8.6e-86 288.8 10.7 1.3e-46 159.5 4.5 2.2 1 1 1 2 2 2 2 HCO3- transporter family Homeodomain PF00046.29 EGO60522.1 - 1.5e-08 34.3 3.2 3.6e-08 33.1 3.2 1.6 1 0 0 1 1 1 1 Homeodomain DUF3292 PF11696.8 EGO60522.1 - 0.42 8.9 2.3 0.61 8.4 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) PPV_E1_N PF00524.18 EGO60522.1 - 1.4 9.4 5.0 0.41 11.1 1.9 1.7 2 0 0 2 2 2 0 E1 Protein, N terminal domain 3HCDH_N PF02737.18 EGO60525.1 - 5.7e-51 172.9 0.2 7.6e-51 172.6 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EGO60525.1 - 2.2e-32 111.5 0.0 4.3e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 EGO60525.1 - 0.00014 22.1 0.1 0.00029 21.1 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 EGO60525.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 EGO60525.1 - 0.03 13.9 0.1 0.041 13.5 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO60525.1 - 0.031 13.5 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TIMELESS PF04821.14 EGO60526.1 - 7.4e-85 284.6 0.0 7.4e-85 284.6 0.0 3.8 3 1 1 4 4 4 1 Timeless protein TIMELESS_C PF05029.13 EGO60526.1 - 7.8e-34 117.8 38.7 7.8e-34 117.8 38.7 3.3 2 1 0 2 2 2 1 Timeless protein C terminal region Nup188_C PF18378.1 EGO60526.1 - 0.071 11.9 0.5 0.19 10.5 0.2 1.8 1 1 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain MFS_1 PF07690.16 EGO60527.1 - 2.1e-44 151.9 48.0 6.7e-44 150.3 48.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO60527.1 - 1e-18 67.4 12.9 1e-18 67.4 12.9 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EGO60527.1 - 2.9e-07 29.3 13.5 2.9e-07 29.3 13.5 2.1 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EGO60527.1 - 1 8.1 30.4 0.69 8.7 16.9 2.4 1 1 2 3 3 3 0 MFS_1 like family MFS_1 PF07690.16 EGO60528.1 - 8.4e-31 107.2 79.1 6.5e-27 94.4 55.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO60528.1 - 0.00055 18.9 11.8 0.00055 18.9 11.8 3.0 1 1 0 2 2 2 1 Sugar (and other) transporter Fungal_trans PF04082.18 EGO60529.1 - 5.9e-12 45.2 0.0 8.2e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAF-AH_p_II PF03403.13 EGO60530.1 - 4.4e-44 150.5 0.0 1.2e-42 145.8 0.0 2.2 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EGO60530.1 - 0.00039 19.4 0.1 0.00097 18.1 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EGO60530.1 - 0.0005 19.4 0.0 0.022 14.0 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 EGO60530.1 - 0.0082 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase DLH PF01738.18 EGO60530.1 - 0.045 13.3 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family UCH PF00443.29 EGO60531.1 - 2.1e-25 89.7 0.1 3.4e-25 89.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGO60531.1 - 4e-12 46.3 0.2 7.7e-12 45.4 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EGO60531.1 - 0.0017 18.0 1.3 0.05 13.2 1.3 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CRISPR_assoc PF08798.11 EGO60531.1 - 0.089 12.9 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 CRISPR associated protein IF4E PF01652.18 EGO60532.1 - 6.9e-54 181.9 0.1 1e-53 181.4 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MTHFR PF02219.17 EGO60533.1 - 3.1e-99 331.9 0.0 4.7e-99 331.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PQ-loop PF04193.14 EGO60535.1 - 3.5e-20 71.5 0.9 6e-15 54.8 0.8 2.4 2 0 0 2 2 2 2 PQ loop repeat DUF1065 PF06358.11 EGO60535.1 - 0.056 13.4 0.5 0.13 12.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) UPF0029 PF01205.19 EGO60536.1 - 5.9e-34 116.6 0.0 1.7e-33 115.1 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EGO60536.1 - 1.3e-09 38.3 0.0 2.7e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 RWD domain ACT_7 PF13840.6 EGO60537.1 - 1.3e-22 79.3 0.1 2.8e-16 59.1 0.0 2.3 2 0 0 2 2 2 2 ACT domain Methyltransf_32 PF13679.6 EGO60538.1 - 1.8e-22 80.0 0.1 2.4e-21 76.3 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EGO60538.1 - 0.0038 16.8 0.1 0.0063 16.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Hormone_3 PF00159.18 EGO60538.1 - 0.14 12.3 0.3 2.9 8.0 0.0 2.9 2 0 0 2 2 2 0 Pancreatic hormone peptide Peptidase_M19 PF01244.21 EGO60539.1 - 5.5e-113 377.3 0.0 6.8e-113 377.0 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) RhoGAP PF00620.27 EGO60540.1 - 2.9e-16 59.6 1.0 1.1e-15 57.8 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 EGO60540.1 - 2e-11 43.7 0.0 4.1e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 EGO60540.1 - 3.4e-10 40.1 0.0 1.3e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BAR PF03114.18 EGO60540.1 - 0.018 14.7 4.4 0.15 11.7 1.4 2.3 2 0 0 2 2 2 0 BAR domain Phage_TAC_8 PF10666.9 EGO60540.1 - 0.063 13.6 0.5 0.21 11.8 0.1 2.1 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 EB1 PF03271.17 EGO60540.1 - 0.16 12.2 0.2 0.5 10.7 0.2 1.9 1 0 0 1 1 1 0 EB1-like C-terminal motif DUF2951 PF11166.8 EGO60540.1 - 0.19 12.0 0.8 1.5 9.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) RVT_1 PF00078.27 EGO60541.1 - 0.0032 17.0 0.0 0.0067 16.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DAO PF01266.24 EGO60542.1 - 2e-75 254.6 0.5 2.4e-75 254.3 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase MCRA PF06100.11 EGO60542.1 - 1.9e-06 27.0 0.1 0.024 13.4 0.0 2.1 2 0 0 2 2 2 2 MCRA family Pyr_redox_2 PF07992.14 EGO60542.1 - 5.1e-06 25.9 0.2 0.0034 16.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGO60542.1 - 1.1e-05 25.9 0.0 0.027 15.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO60542.1 - 1.4e-05 25.2 0.2 3.5e-05 24.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EGO60542.1 - 0.0022 16.9 0.6 0.0071 15.2 0.2 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 EGO60542.1 - 0.033 13.4 0.1 0.055 12.7 0.1 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EGO60542.1 - 0.077 13.0 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EGO60542.1 - 0.086 11.9 0.0 1.8 7.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain GMC_oxred_N PF00732.19 EGO60542.1 - 0.095 12.1 0.1 9.7 5.5 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Amino_oxidase PF01593.24 EGO60542.1 - 0.099 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase GSHPx PF00255.19 EGO60544.1 - 1.9e-42 143.2 0.1 2.5e-42 142.9 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EGO60544.1 - 0.0016 18.4 0.1 0.0043 16.9 0.1 2.0 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.6 EGO60544.1 - 0.0071 16.8 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) Redoxin PF08534.10 EGO60544.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 Redoxin GFO_IDH_MocA PF01408.22 EGO60545.1 - 3.8e-10 40.6 1.7 2.2e-09 38.2 1.7 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EGO60545.1 - 0.12 13.0 0.2 0.2 12.3 0.2 1.5 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DHDPS PF00701.22 EGO60546.1 - 1.6e-31 109.1 0.0 1.8e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.8 EGO60548.1 - 1.1e-50 172.6 0.0 2.2e-50 171.6 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO60548.1 - 6.2e-07 29.4 6.9 1.3e-06 28.4 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop16 PF09420.10 EGO60550.1 - 3.2e-65 220.1 8.5 3.7e-65 219.9 8.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 MARVEL PF01284.23 EGO60551.1 - 2.2e-05 24.5 17.8 3.1e-05 24.1 17.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain Epiglycanin_C PF14654.6 EGO60551.1 - 0.021 14.9 0.1 0.057 13.5 0.1 1.7 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region DUF5134 PF17197.4 EGO60551.1 - 0.17 11.7 2.2 0.25 11.2 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) Kinesin PF00225.23 EGO60552.1 - 3.2e-111 371.5 0.8 9e-111 370.0 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.8 EGO60552.1 - 8.3e-48 162.9 0.5 4.3e-47 160.6 0.0 2.5 2 0 0 2 2 2 1 Kinesin protein Kinesin_assoc PF16183.5 EGO60552.1 - 5.9e-36 124.3 13.1 5.6e-30 104.8 0.3 4.0 2 1 1 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 EGO60552.1 - 1.3e-24 86.8 0.0 5.1e-24 84.9 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 EGO60552.1 - 4e-06 27.2 2.6 4.7e-06 26.9 0.3 2.5 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.29 EGO60552.1 - 0.011 16.3 0.1 9.5 6.8 0.0 3.0 2 0 0 2 2 2 0 PH domain Yop-YscD_cpl PF16697.5 EGO60552.1 - 0.081 13.2 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Peptidase_M1 PF01433.20 EGO60553.1 - 4.7e-43 147.3 0.1 7.5e-43 146.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EGO60553.1 - 1.4e-40 137.9 0.0 2.8e-40 136.9 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EGO60553.1 - 2.5e-31 109.3 0.1 3.8e-31 108.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 EGO60553.1 - 0.01 15.5 0.1 0.17 11.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase MA superfamily SoxY PF13501.6 EGO60553.1 - 0.067 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Sulfur oxidation protein SoxY Peptidase_M61 PF05299.12 EGO60553.1 - 0.12 12.8 1.8 3.6 8.0 1.8 2.7 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DUF3872 PF12988.7 EGO60553.1 - 0.21 11.4 0.3 0.52 10.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3872) Uds1 PF15456.6 EGO60554.1 - 1.3e-15 57.7 15.3 3.1e-13 50.0 2.2 3.4 3 1 1 4 4 4 2 Up-regulated During Septation Glyco_hydro_3_C PF01915.22 EGO60556.1 - 9.6e-30 104.1 0.0 2.2e-29 102.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO60556.1 - 6.5e-23 81.6 0.0 1e-13 51.4 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain G-alpha PF00503.20 EGO60557.1 - 3e-112 375.3 0.5 3.4e-112 375.1 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGO60557.1 - 9e-14 51.3 1.1 1.6e-08 34.2 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGO60557.1 - 0.00038 19.9 0.7 0.081 12.3 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGO60557.1 - 0.0066 16.7 0.3 2.2 8.5 0.1 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 EGO60557.1 - 0.017 14.9 0.9 0.029 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EGO60557.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EGO60557.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.6 EGO60557.1 - 0.21 11.1 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Spermine_synth PF01564.17 EGO60558.1 - 3.6e-76 254.8 0.0 6.3e-76 254.0 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EGO60558.1 - 6.1e-25 86.9 0.1 1e-24 86.2 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EGO60558.1 - 9e-05 23.1 0.0 0.00015 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 EGO60558.1 - 0.0016 17.7 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_12 PF08242.12 EGO60558.1 - 0.0094 16.7 0.2 0.03 15.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 EGO60558.1 - 0.014 16.4 0.0 0.033 15.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EGO60558.1 - 0.037 13.3 0.2 0.11 11.7 0.1 1.9 1 1 1 2 2 2 0 O-methyltransferase domain Methyltransf_18 PF12847.7 EGO60558.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 EGO60558.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Gyro_capsid PF04162.12 EGO60559.1 - 0.014 14.0 0.0 0.02 13.4 0.0 1.2 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) Gln-synt_C PF00120.24 EGO60560.1 - 3.5e-17 62.5 0.0 7.6e-13 48.2 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EGO60560.1 - 3e-13 49.3 0.0 5.6e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain PCRF PF03462.18 EGO60562.1 - 5.3e-50 170.0 0.5 9.6e-50 169.1 0.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EGO60562.1 - 4.9e-34 116.7 3.6 1.2e-33 115.5 3.6 1.6 1 0 0 1 1 1 1 RF-1 domain HAUS6_N PF14661.6 EGO60562.1 - 1.8 8.1 5.5 9.3 5.7 0.2 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Peptidase_S10 PF00450.22 EGO60563.1 - 9.3e-83 278.9 0.1 1.2e-82 278.6 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DWNN PF08783.11 EGO60564.1 - 2.2e-28 98.4 0.0 4e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 EGO60564.1 - 8.3e-09 35.1 5.6 1.5e-08 34.3 5.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGO60564.1 - 0.00067 19.6 0.9 0.0014 18.6 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.15 EGO60564.1 - 0.032 14.4 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 U-box domain zf-CCHC_3 PF13917.6 EGO60564.1 - 0.033 14.1 0.3 0.078 13.0 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-RING_4 PF14570.6 EGO60564.1 - 0.057 13.2 5.7 0.12 12.2 5.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE_2 PF02318.16 EGO60564.1 - 0.13 12.5 0.6 0.36 11.1 0.3 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger Dicty_REP PF05086.12 EGO60564.1 - 0.22 9.4 4.7 0.33 8.9 4.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-C3HC4_4 PF15227.6 EGO60564.1 - 0.34 11.1 10.1 1 9.6 10.1 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EGO60564.1 - 0.43 10.4 5.8 0.99 9.3 5.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 EGO60564.1 - 0.52 10.7 7.4 1.1 9.6 7.4 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 EGO60564.1 - 1.1 9.2 16.5 0.02 14.7 9.5 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO60564.1 - 4 7.6 8.2 8.2 6.6 8.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger SOBP PF15279.6 EGO60564.1 - 9.4 6.7 33.9 1.3 9.6 26.2 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein Endostatin PF06482.11 EGO60564.1 - 9.7 5.6 13.1 22 4.4 9.5 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin ArsA_ATPase PF02374.15 EGO60566.1 - 5.4e-113 377.2 0.0 6.2e-113 377.0 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EGO60566.1 - 5.4e-13 49.2 0.4 1.1e-11 45.0 0.0 2.7 2 2 0 2 2 2 1 AAA domain CbiA PF01656.23 EGO60566.1 - 3.5e-12 46.5 0.0 6.7e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EGO60566.1 - 1.2e-06 28.2 0.5 0.00022 20.8 0.1 2.4 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 EGO60566.1 - 5.7e-06 26.0 0.0 9.1e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EGO60566.1 - 3.3e-05 23.6 0.3 0.0016 18.1 0.0 2.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 EGO60566.1 - 0.00013 21.5 0.0 0.00033 20.2 0.0 1.6 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 EGO60566.1 - 0.033 14.6 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EGO60566.1 - 0.046 13.3 0.0 0.093 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGO60566.1 - 0.052 12.7 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RecG_N PF17190.4 EGO60566.1 - 0.11 13.2 1.3 0.43 11.3 0.5 2.3 2 0 0 2 2 2 0 RecG N-terminal helical domain AAA_18 PF13238.6 EGO60566.1 - 0.13 12.8 0.0 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGO60566.1 - 0.14 11.6 0.0 0.42 10.0 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein TRAPPC9-Trs120 PF08626.11 EGO60567.1 - 0 1382.2 0.0 0 1381.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit adh_short PF00106.25 EGO60567.1 - 1.4e-18 67.1 0.0 2.5e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO60567.1 - 1.8e-14 53.9 0.0 3.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO60567.1 - 0.065 13.1 0.0 0.31 10.9 0.0 2.2 2 1 0 2 2 2 0 KR domain Chorismate_bind PF00425.18 EGO60568.1 - 3.8e-68 229.9 0.1 1.3e-67 228.1 0.1 1.9 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EGO60568.1 - 8e-19 68.1 0.0 2.4e-17 63.4 0.0 2.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EGO60568.1 - 1.7e-09 38.0 0.0 1.2e-08 35.3 0.0 2.3 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EGO60568.1 - 0.00016 21.5 1.0 0.13 12.0 0.3 2.3 2 0 0 2 2 2 2 Peptidase C26 Vps55 PF04133.14 EGO60569.1 - 6.8e-43 145.4 10.3 7.7e-43 145.2 10.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 ABC2_membrane_3 PF12698.7 EGO60569.1 - 4.1 6.4 11.7 4.6 6.3 11.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Proteasome PF00227.26 EGO60570.1 - 1.5e-50 171.3 0.1 1.9e-50 171.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGO60570.1 - 2.2e-11 43.2 0.2 3.6e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Lysine_decarbox PF03641.14 EGO60571.1 - 2.7e-30 105.2 0.1 4.2e-30 104.5 0.1 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EGO60571.1 - 3.1e-05 23.6 0.4 0.00071 19.2 0.1 2.2 2 0 0 2 2 2 1 SLOG cluster4 family Spt5-NGN PF03439.13 EGO60571.1 - 0.084 12.8 0.1 1.4 8.9 0.1 2.2 2 0 0 2 2 2 0 Early transcription elongation factor of RNA pol II, NGN section CLPTM1 PF05602.12 EGO60572.1 - 1.8e-155 518.2 0.2 2.2e-155 517.9 0.2 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1453 PF07301.11 EGO60572.1 - 0.022 14.7 4.4 0.47 10.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) DUF4711 PF15829.5 EGO60573.1 - 1.6 8.6 4.0 5.9 6.8 1.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4711) AIF_C PF14721.6 EGO60573.1 - 3.8 7.9 5.5 3.3 8.1 1.2 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term ASXH PF13919.6 EGO60574.1 - 9.9e-36 122.8 0.5 9.9e-36 122.8 0.5 1.9 2 0 0 2 2 2 1 Asx homology domain HC2 PF07382.11 EGO60574.1 - 2.1e-09 37.7 22.6 2.1e-09 37.7 22.6 3.2 4 2 0 4 4 4 1 Histone H1-like nucleoprotein HC2 Elong_Iki1 PF10483.9 EGO60575.1 - 3.5e-103 345.2 0.0 4.2e-103 345.0 0.0 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 SNRNP27 PF08648.12 EGO60576.1 - 3e-27 94.4 2.6 3e-27 94.4 2.6 4.2 5 0 0 5 5 5 1 U4/U6.U5 small nuclear ribonucleoproteins SMAP PF15477.6 EGO60576.1 - 5.4e-09 36.9 4.0 5.4e-09 36.9 4.0 6.0 3 1 0 3 3 3 1 Small acidic protein family RAMP4 PF06624.12 EGO60577.1 - 5e-22 77.7 0.3 5.5e-22 77.6 0.3 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF3094 PF11293.8 EGO60577.1 - 0.05 13.3 0.1 0.072 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) TIM21 PF08294.11 EGO60577.1 - 0.26 11.2 1.6 0.28 11.0 1.1 1.4 1 1 0 1 1 1 0 TIM21 FlxA PF14282.6 EGO60578.1 - 0.03 14.3 2.8 0.03 14.3 2.8 2.0 2 0 0 2 2 2 0 FlxA-like protein DUF2681 PF10883.8 EGO60578.1 - 0.057 13.8 2.0 0.12 12.8 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF3138 PF11336.8 EGO60578.1 - 0.12 10.9 0.8 0.14 10.7 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Mid1 PF12929.7 EGO60579.1 - 2.4e-152 508.0 5.8 3e-152 507.7 5.8 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EGO60579.1 - 0.00011 22.8 4.8 0.0037 17.9 1.6 2.6 2 0 0 2 2 2 2 Fz domain TB2_DP1_HVA22 PF03134.19 EGO60580.1 - 1.4e-27 95.4 9.0 2.5e-27 94.6 9.0 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4407 PF14362.6 EGO60580.1 - 0.028 13.8 0.2 0.84 8.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RFX_DNA_binding PF02257.15 EGO60581.1 - 7.5e-28 97.0 0.1 1.8e-27 95.8 0.1 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EGO60581.1 - 0.09 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Hydrolase_4 PF12146.8 EGO60582.1 - 3.1e-48 164.1 0.0 3.7e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO60582.1 - 4.5e-14 52.7 1.0 2.8e-13 50.1 0.9 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO60582.1 - 1e-12 49.2 0.9 5.5e-12 46.8 0.5 1.8 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EGO60582.1 - 0.011 15.6 0.0 3 7.6 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase ECH_1 PF00378.20 EGO60582.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Esterase PF00756.20 EGO60582.1 - 0.13 11.8 0.0 0.59 9.7 0.0 1.8 2 0 0 2 2 2 0 Putative esterase Cation_efflux PF01545.21 EGO60583.1 - 5.3e-17 62.2 7.5 6.5e-17 61.9 7.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGO60583.1 - 1.3e-10 41.2 0.4 1.3e-10 41.2 0.4 1.6 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter lci PF12197.8 EGO60583.1 - 0.066 13.0 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein Glyco_transf_8 PF01501.20 EGO60584.1 - 2.1e-24 86.5 0.9 3.9e-23 82.3 0.9 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EGO60584.1 - 0.016 14.6 0.0 0.016 14.6 0.0 1.6 2 0 0 2 2 2 0 Mannosyltransferase putative Prok-E2_E PF14462.6 EGO60584.1 - 0.25 11.1 3.3 3.3 7.5 0.1 2.6 2 1 0 2 2 2 0 Prokaryotic E2 family E 3-PAP PF12578.8 EGO60584.1 - 1 9.1 4.7 31 4.3 4.0 2.4 2 0 0 2 2 2 0 Myotubularin-associated protein ABC_tran_CTD PF16326.5 EGO60586.1 - 0.0036 17.5 5.3 0.0036 17.5 5.3 4.4 3 1 1 4 4 4 2 ABC transporter C-terminal domain T3SSipB PF16535.5 EGO60586.1 - 0.0063 17.0 14.7 0.0063 17.0 14.7 4.3 3 1 1 4 4 4 1 Type III cell invasion protein SipB HDA2-3 PF11496.8 EGO60586.1 - 0.026 13.7 0.0 7.8 5.6 0.0 2.5 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Bcr-Abl_Oligo PF09036.10 EGO60586.1 - 0.15 12.1 4.7 20 5.3 0.3 4.1 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain DUF724 PF05266.14 EGO60586.1 - 4.6 7.0 21.1 13 5.5 7.0 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) NYD-SP28_assoc PF14775.6 EGO60586.1 - 5.4 7.2 5.3 5.3 7.2 0.0 3.2 3 0 0 3 3 3 0 Sperm tail C-terminal domain YabA PF06156.13 EGO60586.1 - 9.6 6.9 14.1 3.2 8.4 4.9 3.7 3 1 0 3 3 3 0 Initiation control protein YabA COX5A PF02284.16 EGO60587.1 - 2.4e-41 139.9 0.2 3.1e-41 139.6 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ELO PF01151.18 EGO60588.1 - 4.2e-62 209.9 17.8 5e-62 209.7 17.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Metallophos_2 PF12850.7 EGO60592.1 - 5.4e-08 33.2 0.0 3.1e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EGO60592.1 - 1.9e-06 28.5 0.0 3.2e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase F-box-like PF12937.7 EGO60593.1 - 2.1e-05 24.3 0.4 5.9e-05 22.9 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO60593.1 - 8 6.5 7.8 15 5.6 4.2 2.8 2 1 0 2 2 2 0 F-box domain Glycogen_syn PF05693.13 EGO60594.1 - 0 1198.5 0.0 0 1198.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 EGO60594.1 - 3.2e-05 24.0 0.4 7e-05 22.9 0.4 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 EGO60594.1 - 3.7e-05 23.6 0.1 7.6e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EGO60594.1 - 9.3e-05 22.0 0.0 0.02 14.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGO60594.1 - 0.00025 21.5 0.0 0.2 12.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGO60594.1 - 0.0019 18.7 0.0 0.0042 17.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Pkinase PF00069.25 EGO60597.1 - 2.8e-71 240.0 0.0 3.9e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO60597.1 - 2.5e-35 122.0 0.0 3.9e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO60597.1 - 0.00084 18.7 0.2 0.0038 16.6 0.1 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGO60597.1 - 0.041 13.2 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGO60597.1 - 0.042 13.5 0.1 0.078 12.6 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 EGO60597.1 - 0.083 11.8 0.6 0.26 10.2 0.1 1.8 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EGO60597.1 - 0.36 9.5 0.0 0.36 9.5 0.0 2.9 4 0 0 4 4 4 0 Fungal protein kinase zf-RanBP PF00641.18 EGO60598.1 - 2.4e-18 65.1 13.3 8.5e-11 41.0 1.6 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 EGO60598.1 - 3.9e-08 33.0 0.0 8e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 EGO60598.1 - 2.1e-07 31.6 0.0 3.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Pmp3 PF01679.17 EGO60600.1 - 6.1e-21 74.4 9.4 7.5e-21 74.1 9.4 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SUIM_assoc PF16619.5 EGO60601.1 - 3.6 7.7 8.2 1.4 9.0 3.2 2.9 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 EGO60602.1 - 1.9 8.4 16.8 5.4 6.9 16.8 1.8 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAF1C_H4-bd PF12265.8 EGO60603.1 - 6.1e-28 96.9 0.2 6.4e-27 93.6 0.3 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGO60603.1 - 2.1e-21 75.8 7.2 2.5e-05 24.9 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO60603.1 - 6.7e-06 26.3 0.1 0.015 15.6 0.0 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 EGO60603.1 - 0.0016 18.1 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region XRN_N PF03159.18 EGO60604.1 - 1.3e-97 326.0 0.0 2.2e-97 325.3 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 EGO60604.1 - 1.9e-79 265.9 0.0 3.3e-79 265.1 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 EGO60604.1 - 6.4e-33 112.8 0.0 2.1e-32 111.2 0.0 2.0 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 EGO60604.1 - 1.5e-22 79.5 0.3 2.9e-22 78.5 0.3 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN_M PF17846.1 EGO60604.1 - 8.4e-06 25.0 0.2 1.4e-05 24.3 0.2 1.2 1 0 0 1 1 1 1 Xrn1 helical domain Xrn1_D3 PF18194.1 EGO60604.1 - 0.00034 20.6 0.0 0.00069 19.7 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 SPC22 PF04573.12 EGO60605.1 - 6.6e-41 139.6 4.5 8.6e-40 136.0 4.5 2.0 1 1 0 1 1 1 1 Signal peptidase subunit Hid1 PF12722.7 EGO60606.1 - 4.6e-296 984.3 0.0 5.2e-296 984.1 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EGO60606.1 - 2.6e-96 323.5 0.0 3.4e-96 323.1 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein MEKHLA PF08670.11 EGO60606.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 MEKHLA domain EHN PF06441.12 EGO60607.1 - 1.4e-25 89.8 0.1 2.8e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus NPCC PF08058.11 EGO60608.1 - 5e-24 84.8 0.0 7.2e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex component Baculo_11_kDa PF06143.11 EGO60609.1 - 0.016 14.8 1.0 0.018 14.6 0.4 1.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family TMEM154 PF15102.6 EGO60609.1 - 0.14 12.1 0.1 0.15 12.0 0.1 1.1 1 0 0 1 1 1 0 TMEM154 protein family dCMP_cyt_deam_1 PF00383.23 EGO60610.1 - 1.2e-27 95.8 1.1 1.8e-27 95.2 1.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGO60610.1 - 2.5e-12 46.7 0.1 3.9e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 EGO60610.1 - 5.9e-09 36.5 0.1 2.6e-08 34.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGO60610.1 - 0.0011 19.1 0.1 0.0028 17.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 EGO60610.1 - 0.0058 16.3 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 Dephospho-CoA kinase Dynamin_N PF00350.23 EGO60610.1 - 0.0097 16.0 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin family XOO_2897-deam PF14440.6 EGO60610.1 - 0.093 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase AAA_28 PF13521.6 EGO60610.1 - 0.25 11.6 1.7 0.55 10.5 0.6 2.2 2 1 0 2 2 2 0 AAA domain ATG7_N PF16420.5 EGO60611.1 - 5.3e-113 377.6 0.0 7e-113 377.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EGO60611.1 - 1.4e-47 162.1 0.0 2.1e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EGO60611.1 - 0.1 12.6 0.0 0.73 9.9 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3405 PF11885.8 EGO60614.1 - 2.4e-154 514.8 0.5 1.5e-100 337.3 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) LIM PF00412.22 EGO60615.1 - 4.6e-22 78.0 15.0 4.3e-12 46.1 3.6 2.2 2 0 0 2 2 2 2 LIM domain TFIIA PF03153.13 EGO60615.1 - 5.6 6.9 22.0 0.81 9.6 12.8 2.9 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit NAD_binding_5 PF07994.12 EGO60618.1 - 1.2e-144 481.7 0.0 1.5e-144 481.3 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EGO60618.1 - 3.2e-44 149.6 0.5 6.8e-44 148.6 0.3 1.7 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase tRNA_anti-codon PF01336.25 EGO60619.1 - 9.5e-05 22.3 0.0 0.0044 17.0 0.0 2.6 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain AMP-binding PF00501.28 EGO60620.1 - 4.7e-85 285.7 0.0 5.8e-85 285.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGO60620.1 - 5.4e-11 43.3 0.0 1.2e-10 42.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peripla_BP_6 PF13458.6 EGO60620.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Auto_anti-p27 PF06677.12 EGO60620.1 - 0.8 9.9 3.6 1.3 9.2 2.1 2.2 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Translin PF01997.16 EGO60621.1 - 4.8e-45 154.1 0.0 5.6e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Translin family Tnp_22_dsRBD PF17490.2 EGO60621.1 - 0.069 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 L1 transposable element dsRBD-like domain PIG-F PF06699.11 EGO60622.1 - 5.8e-66 222.1 1.9 7.6e-66 221.7 1.9 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Mito_carr PF00153.27 EGO60623.1 - 3.2e-54 180.8 0.8 7.5e-18 64.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L22e PF01776.17 EGO60624.1 - 4.2e-44 149.4 1.1 5.2e-44 149.1 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family MMR_HSR1_C PF08438.10 EGO60626.1 - 2e-37 128.2 0.0 4.3e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EGO60626.1 - 6.1e-17 61.7 0.0 2.1e-16 60.0 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGO60626.1 - 3e-05 23.6 0.1 0.0012 18.4 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGO60626.1 - 0.002 18.1 0.8 0.13 12.1 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EGO60626.1 - 0.0051 16.9 0.4 0.11 12.6 0.1 2.8 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 EGO60626.1 - 0.019 14.5 0.2 0.8 9.2 0.0 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 EGO60626.1 - 0.098 12.7 0.1 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 EGO60626.1 - 0.12 12.8 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AIG1 PF04548.16 EGO60626.1 - 0.14 11.5 0.1 0.5 9.6 0.0 1.9 2 0 0 2 2 2 0 AIG1 family SET PF00856.28 EGO60627.1 - 7.7e-06 26.4 0.0 1.5e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 SET domain Fungal_trans PF04082.18 EGO60629.1 - 4.5e-34 117.7 0.2 9.4e-34 116.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO60629.1 - 4.8e-08 33.0 14.9 4.8e-08 33.0 14.9 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Presenilin PF01080.17 EGO60629.1 - 0.26 10.0 5.2 0.44 9.3 5.2 1.3 1 0 0 1 1 1 0 Presenilin DUF1192 PF06698.11 EGO60629.1 - 0.32 11.1 2.7 0.85 9.7 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Suf PF05843.14 EGO60629.1 - 5.6 6.9 18.9 13 5.6 18.9 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GDPD PF03009.17 EGO60632.1 - 5.7e-26 91.8 0.0 1e-25 90.9 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EGO60632.1 - 9.1e-05 22.8 0.6 0.00025 21.4 0.6 1.8 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF676 PF05057.14 EGO60633.1 - 5.4e-56 189.6 0.0 8.5e-56 188.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EGO60633.1 - 0.0032 18.1 0.3 0.013 16.1 0.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EGO60633.1 - 0.0069 16.3 0.0 0.014 15.3 0.0 1.4 2 0 0 2 2 2 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGO60633.1 - 0.013 15.2 0.1 0.086 12.6 0.1 2.0 1 1 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 EGO60633.1 - 0.033 14.0 0.1 0.082 12.8 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Lipase_2 PF01674.18 EGO60633.1 - 0.22 11.0 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) HhH-GPD PF00730.25 EGO60634.1 - 4e-17 62.6 0.0 1.1e-16 61.2 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGO60634.1 - 1.2e-08 34.4 0.0 2.7e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif ADH_N PF08240.12 EGO60635.1 - 9.8e-27 93.0 1.5 2.1e-26 91.9 1.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGO60635.1 - 1e-21 77.3 0.1 2.1e-21 76.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGO60635.1 - 0.0005 19.4 0.3 0.00087 18.7 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 EGO60635.1 - 0.0014 18.1 0.2 0.01 15.3 0.2 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 EGO60635.1 - 0.0021 17.5 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 EGO60635.1 - 0.022 15.8 0.0 0.042 14.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase F420_oxidored PF03807.17 EGO60635.1 - 0.023 15.3 0.2 0.19 12.3 0.0 2.5 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 EGO60635.1 - 0.072 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Imm70 PF15601.6 EGO60635.1 - 0.12 11.9 0.0 0.36 10.4 0.0 1.8 1 0 0 1 1 1 0 Immunity protein 70 zf-AN1 PF01428.16 EGO60636.1 - 1.7e-11 44.1 5.1 1.7e-11 44.1 5.1 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Phospholip_A2_3 PF09056.11 EGO60637.1 - 2.6e-43 147.1 1.1 3.3e-43 146.8 1.1 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 DUF1349 PF07081.11 EGO60637.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) Nucleopor_Nup85 PF07575.13 EGO60638.1 - 6.1e-17 61.4 0.0 2.9e-08 32.8 0.0 2.5 2 1 0 2 2 2 2 Nup85 Nucleoporin SAM_2 PF07647.17 EGO60639.1 - 3.8e-15 55.7 0.0 6.2e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 EGO60639.1 - 4.6e-14 52.0 0.0 9.8e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGO60639.1 - 3.6e-12 45.7 0.0 8.3e-12 44.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 EGO60639.1 - 2.2e-09 37.8 0.0 1.2e-08 35.4 0.0 2.1 1 1 0 1 1 1 1 PH domain SH3_2 PF07653.17 EGO60639.1 - 8.1e-05 22.2 0.0 0.00017 21.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 EGO60639.1 - 0.016 15.7 0.1 0.049 14.1 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Gastrin PF00918.17 EGO60639.1 - 0.13 13.2 2.6 0.22 12.5 0.1 2.7 2 1 0 2 2 2 0 Gastrin/cholecystokinin family SAM_1 PF00536.30 EGO60639.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) ECH_1 PF00378.20 EGO60640.1 - 3.7e-36 124.7 0.1 1.4e-35 122.9 0.1 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGO60640.1 - 2.4e-30 106.2 0.0 3.7e-27 95.7 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Ran_BP1 PF00638.18 EGO60642.1 - 1.7e-16 60.6 0.0 5.4e-16 59.0 0.0 1.7 1 1 0 1 1 1 1 RanBP1 domain SCP2 PF02036.17 EGO60643.1 - 2.9e-24 85.5 0.4 3.3e-24 85.3 0.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EGO60643.1 - 5.6e-07 29.9 0.2 7e-07 29.6 0.2 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 EGO60643.1 - 0.0012 19.2 0.1 0.0015 18.9 0.1 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain Pkinase PF00069.25 EGO60648.1 - 5.2e-52 176.8 0.0 7.7e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO60648.1 - 3.4e-20 72.4 0.0 6.2e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGO60648.1 - 0.035 14.0 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGO60648.1 - 0.18 11.4 0.4 0.33 10.5 0.4 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pex24p PF06398.11 EGO60649.1 - 4.2e-90 302.4 0.0 5e-90 302.1 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.12 EGO60649.1 - 0.14 11.6 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) CDC14 PF08045.11 EGO60650.1 - 1.1e-110 369.3 0.0 1.2e-110 369.1 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component polyprenyl_synt PF00348.17 EGO60651.1 - 3e-65 219.8 0.0 3.7e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Na_H_Exchanger PF00999.21 EGO60652.1 - 0.062 12.1 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family SKG6 PF08693.10 EGO60652.1 - 0.072 12.5 0.7 0.16 11.4 0.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LapA_dom PF06305.11 EGO60652.1 - 0.14 12.0 1.0 0.31 10.9 1.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain GFA PF04828.14 EGO60654.1 - 1.3e-24 86.3 0.0 2e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 EGO60654.1 - 0.71 9.9 4.7 3 8.0 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon DUF1365 PF07103.11 EGO60655.1 - 1.2e-63 215.1 0.4 2e-63 214.3 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) MBF1 PF08523.10 EGO60656.1 - 1.4e-23 83.1 1.2 1.4e-23 83.1 1.2 1.6 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EGO60656.1 - 1.1e-09 38.2 0.0 2.6e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EGO60656.1 - 0.00079 19.7 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EGO60656.1 - 0.032 14.3 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain CDT1_C PF16679.5 EGO60657.1 - 4.2e-25 88.0 0.3 4.2e-25 88.0 0.3 2.7 3 0 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain RVT_thumb PF06817.14 EGO60657.1 - 0.076 12.9 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Reverse transcriptase thumb domain DLH PF01738.18 EGO60658.1 - 1.3e-06 28.2 0.0 7.9e-06 25.6 0.0 2.1 2 1 0 2 2 2 1 Dienelactone hydrolase family ADH_zinc_N PF00107.26 EGO60659.1 - 1.8e-25 89.4 0.2 4.2e-25 88.2 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGO60659.1 - 1e-23 84.8 0.0 1.7e-23 84.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGO60659.1 - 1.8e-09 37.5 0.0 2.7e-08 33.7 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF735 PF05246.11 EGO60659.1 - 0.033 14.2 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF735) ATG_C PF09333.11 EGO60660.1 - 0.15 12.4 0.2 0.46 10.9 0.0 1.9 1 1 1 2 2 2 0 Autophagy-related protein C terminal domain AMP-binding PF00501.28 EGO60661.1 - 3.7e-73 246.5 0.0 4.8e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGO60661.1 - 3.1e-19 68.6 0.6 8.4e-19 67.2 0.6 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGO60661.1 - 3.8e-13 50.2 0.0 8.1e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain KilA-N PF04383.13 EGO60665.1 - 0.0007 19.4 0.0 0.013 15.3 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain Fungal_TACC PF12709.7 EGO60666.1 - 1.3e-12 48.0 21.1 8e-12 45.4 4.9 4.0 3 1 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins Macoilin PF09726.9 EGO60666.1 - 0.00013 20.7 9.3 0.00013 20.7 9.3 2.5 2 1 1 3 3 3 1 Macoilin family GIT_CC PF16559.5 EGO60666.1 - 0.045 13.6 0.4 0.045 13.6 0.4 2.8 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlaC_arch PF05377.11 EGO60666.1 - 0.11 12.9 23.4 2.5 8.6 0.7 5.5 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Shugoshin_N PF07558.11 EGO60666.1 - 0.51 10.2 3.8 5.8 6.9 1.2 3.1 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF4407 PF14362.6 EGO60666.1 - 0.59 9.4 22.7 1.7 7.9 12.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 EGO60666.1 - 1.3 9.5 7.6 1.7e+02 2.8 0.0 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein NYD-SP28_assoc PF14775.6 EGO60666.1 - 3.4 7.8 5.0 35 4.6 0.2 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain Fez1 PF06818.15 EGO60666.1 - 4.7 7.6 36.5 11 6.4 15.8 2.5 1 1 1 2 2 2 0 Fez1 Filament PF00038.21 EGO60666.1 - 5.5 6.5 35.8 9.2 5.7 14.6 2.9 1 1 0 1 1 1 0 Intermediate filament protein Aldedh PF00171.22 EGO60667.1 - 6.2e-15 54.7 13.5 3.7e-10 38.9 10.1 2.8 1 1 1 2 2 2 2 Aldehyde dehydrogenase family MFS_1 PF07690.16 EGO60668.1 - 4.2e-50 170.6 30.7 4.2e-50 170.6 30.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EGO60668.1 - 6.3e-07 29.0 3.8 6.3e-07 29.0 3.8 3.2 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB PUCC PF03209.15 EGO60668.1 - 3e-05 23.2 0.7 3e-05 23.2 0.7 2.8 2 1 0 2 2 2 1 PUCC protein PTR2 PF00854.21 EGO60668.1 - 0.019 13.8 5.6 0.3 9.9 2.2 2.3 1 1 1 2 2 2 0 POT family INO80_Ies4 PF08193.11 EGO60670.1 - 1.8e-84 283.5 12.6 1.8e-84 283.5 12.6 1.8 2 0 0 2 2 2 1 INO80 complex subunit Ies4 CLTH PF10607.9 EGO60672.1 - 9.1e-37 126.2 0.1 1.3e-36 125.7 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 EGO60672.1 - 4.1e-22 78.5 0.1 8.3e-22 77.5 0.1 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 EGO60672.1 - 1e-05 25.3 0.2 3e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 LisH DUF4932 PF16286.5 EGO60672.1 - 0.11 11.8 0.1 0.66 9.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4932) PCI PF01399.27 EGO60673.1 - 0.00085 19.8 0.0 0.0023 18.4 0.0 1.7 2 0 0 2 2 2 1 PCI domain SNF2_N PF00176.23 EGO60675.1 - 3e-50 170.9 0.2 9.7e-50 169.2 0.2 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-PHD-like PF15446.6 EGO60675.1 - 6.8e-30 103.9 0.4 6.8e-30 103.9 0.4 2.3 3 0 0 3 3 3 1 PHD/FYVE-zinc-finger like domain Helicase_C PF00271.31 EGO60675.1 - 1.2e-18 67.4 0.0 3.7e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EGO60675.1 - 7.7e-10 38.4 0.4 2e-09 37.0 0.4 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EGO60675.1 - 3e-05 24.1 0.0 7.1e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Chromo PF00385.24 EGO60675.1 - 6.7e-05 22.7 0.6 0.0029 17.5 0.1 3.4 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.29 EGO60675.1 - 0.0002 21.2 0.0 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 EGO60675.1 - 0.036 13.7 0.0 0.087 12.4 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 AGH PF17558.2 EGO60675.1 - 9 6.5 8.2 4.7 7.4 1.2 3.0 2 1 1 3 3 3 0 Androgenic gland hormone SpoU_methylase PF00588.19 EGO60676.1 - 1.1e-26 93.7 0.0 1.9e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family IDO PF01231.18 EGO60678.1 - 3.1e-32 111.9 0.0 4.2e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase GST_N_4 PF17172.4 EGO60679.1 - 1.5e-15 57.7 0.0 3.3e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EGO60679.1 - 6.9e-09 35.4 0.0 1.5e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO60679.1 - 0.00023 21.1 0.0 0.00046 20.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EGO60679.1 - 0.0003 21.1 0.0 0.00082 19.7 0.0 1.8 2 1 0 2 2 2 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 EGO60679.1 - 0.0067 16.7 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex adh_short_C2 PF13561.6 EGO60681.1 - 4.4e-42 144.3 0.2 6.8e-42 143.6 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO60681.1 - 4.7e-39 133.9 0.0 8.5e-39 133.0 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO60681.1 - 2e-09 37.6 0.1 3.2e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 KR domain TPMT PF05724.11 EGO60682.1 - 1.9e-17 63.6 0.3 9.2e-17 61.4 0.3 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 EGO60682.1 - 0.0021 18.7 0.0 0.033 14.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGO60682.1 - 0.0048 16.3 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_23 PF13489.6 EGO60682.1 - 0.0064 16.3 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO60682.1 - 0.018 15.7 0.0 0.089 13.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGO60682.1 - 0.16 12.7 0.0 0.43 11.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain OTU PF02338.19 EGO60683.1 - 7.3e-24 84.7 1.1 1.8e-23 83.4 0.0 2.1 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGO60683.1 - 9e-05 22.0 0.3 0.0042 16.6 0.0 2.8 3 0 0 3 3 3 1 Peptidase C65 Otubain CDC27 PF09507.10 EGO60683.1 - 0.15 11.4 19.6 0.21 10.9 19.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1996 PF09362.10 EGO60685.1 - 1.3e-84 283.9 1.8 1.8e-84 283.4 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Glyco_hydro_18 PF00704.28 EGO60687.1 - 3.8e-11 43.3 0.0 4.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Med3 PF11593.8 EGO60687.1 - 0.075 12.2 3.7 0.1 11.8 3.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal UPF0560 PF10577.9 EGO60687.1 - 0.091 11.3 2.0 0.11 11.0 2.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF572 PF04502.13 EGO60690.1 - 1.7e-52 179.2 9.2 3.5e-52 178.1 9.2 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF3449 PF11931.8 EGO60690.1 - 6.5 6.5 11.1 0.087 12.6 1.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3449) WD40 PF00400.32 EGO60691.1 - 3.8e-23 81.3 10.9 0.00053 20.7 0.5 7.0 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO60691.1 - 9.2e-10 38.7 0.0 0.037 14.3 0.0 5.4 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO60691.1 - 0.07 11.8 1.1 1.2 7.7 0.0 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PQQ PF01011.21 EGO60691.1 - 1.8 8.7 5.1 48 4.1 0.0 4.2 4 0 0 4 4 4 0 PQQ enzyme repeat Glyco_transf_15 PF01793.16 EGO60692.1 - 1.1e-114 383.1 9.7 1.3e-114 382.8 9.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GCP_N_terminal PF17681.1 EGO60693.1 - 2.1e-36 126.1 0.0 3.5e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGO60693.1 - 9.9e-30 104.0 0.3 9.9e-30 104.0 0.3 2.4 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 EGO60693.1 - 0.00059 18.3 0.1 0.0037 15.7 0.0 2.2 3 0 0 3 3 3 1 gamma-Tubulin ring complex non-core subunit mod21 DUF4298 PF14131.6 EGO60693.1 - 0.14 12.1 0.5 0.55 10.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Fungal_trans PF04082.18 EGO60694.1 - 6.8e-14 51.5 0.1 9.5e-14 51.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO60694.1 - 4.3e-08 33.1 9.3 8.8e-08 32.1 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3433 PF11915.8 EGO60699.1 - 1.2e-13 51.4 1.2 1.2e-13 51.4 1.2 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3433) TadZ_N PF16968.5 EGO60699.1 - 0.00077 19.2 0.2 0.0018 18.0 0.2 1.5 1 0 0 1 1 1 1 Pilus assembly protein TadZ N-terminal GGACT PF06094.12 EGO60700.1 - 6.8e-20 71.9 0.3 9.4e-20 71.4 0.3 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF4932 PF16286.5 EGO60700.1 - 0.027 13.8 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4932) Glyco_hydro_61 PF03443.14 EGO60701.1 - 0.0075 16.2 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 FAT PF02259.23 EGO60702.1 - 8e-75 252.2 6.8 1.6e-74 251.2 6.8 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EGO60702.1 - 2.3e-29 102.9 0.0 6.5e-29 101.5 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EGO60702.1 - 4.3e-05 23.2 0.2 0.00012 21.8 0.2 1.9 1 0 0 1 1 1 1 FATC domain FANCI_S3 PF14677.6 EGO60702.1 - 9.9 5.8 7.5 1.7 8.3 0.1 3.5 4 0 0 4 4 4 0 FANCI solenoid 3 AMP-binding PF00501.28 EGO60703.1 - 9.1e-45 153.0 0.0 1.3e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGO60703.1 - 1e-07 31.8 0.2 2.4e-07 30.6 0.2 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Esterase_phd PF10503.9 EGO60703.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase AMP-binding_C PF13193.6 EGO60703.1 - 0.066 14.2 0.0 0.17 12.9 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain TPR_2 PF07719.17 EGO60704.1 - 1.1e-31 106.4 18.1 0.00022 21.1 0.0 10.7 11 0 0 11 11 10 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO60704.1 - 8.1e-29 99.7 17.5 3.5e-22 78.4 1.4 5.3 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EGO60704.1 - 9.4e-29 98.0 16.0 3.3e-05 23.5 1.2 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGO60704.1 - 8.1e-28 96.7 18.2 0.00064 20.2 0.1 8.0 5 2 3 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 EGO60704.1 - 1.2e-24 86.4 24.1 4.1e-11 43.0 0.5 9.2 7 1 2 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 EGO60704.1 - 2.5e-22 77.6 17.8 0.00014 22.4 0.0 9.8 5 1 5 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGO60704.1 - 5.4e-22 76.1 8.2 0.0012 18.9 0.5 9.5 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGO60704.1 - 8.5e-20 71.1 20.4 1.8e-05 25.2 0.2 9.0 7 2 0 8 8 8 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGO60704.1 - 6.4e-18 64.0 16.0 5.4e-05 22.9 0.1 8.5 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGO60704.1 - 9.9e-14 50.8 7.2 0.0017 18.0 0.0 7.3 5 2 2 7 7 7 4 TPR repeat TPR_7 PF13176.6 EGO60704.1 - 1.1e-12 47.0 14.6 0.034 14.2 0.0 8.7 10 1 1 11 11 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGO60704.1 - 5.5e-10 39.2 12.7 0.13 13.0 0.5 8.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGO60704.1 - 4.6e-09 36.3 4.6 0.016 15.4 0.4 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 EGO60704.1 - 4e-08 33.1 14.3 0.66 10.8 0.1 8.6 8 1 1 9 9 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGO60704.1 - 7.4e-06 25.4 3.0 0.024 13.8 0.0 5.4 3 2 4 7 7 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGO60704.1 - 0.00028 20.4 10.5 0.0016 17.9 2.0 3.9 4 1 1 5 5 5 1 MalT-like TPR region TPR_21 PF09976.9 EGO60704.1 - 0.00096 18.9 16.9 0.18 11.5 0.1 5.3 5 1 2 7 7 7 2 Tetratricopeptide repeat-like domain TPR_3 PF07720.12 EGO60704.1 - 0.0013 18.6 0.6 19 5.4 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.7 EGO60704.1 - 0.0034 17.6 0.5 0.029 14.6 0.1 2.8 2 1 1 3 3 2 1 Tetratrico peptide repeat HrpB1_HrpK PF09613.10 EGO60704.1 - 0.0045 16.6 0.1 0.15 11.7 0.0 3.0 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_17 PF13431.6 EGO60704.1 - 0.0073 16.6 11.8 14 6.4 0.0 7.6 9 1 0 9 9 7 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EGO60704.1 - 0.018 15.0 2.0 11 6.1 0.0 4.0 3 2 1 4 4 4 0 Putative TPR-like repeat HemY_N PF07219.13 EGO60704.1 - 0.15 12.3 3.3 4.4 7.5 0.0 4.3 4 0 0 4 4 4 0 HemY protein N-terminus Fis1_TPR_C PF14853.6 EGO60704.1 - 0.79 9.8 6.7 12 6.0 0.2 4.9 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF4810 PF16068.5 EGO60704.1 - 1.3 9.6 4.0 41 4.8 0.0 4.2 6 0 0 6 6 3 0 Domain of unknown function (DUF4810) Alk_phosphatase PF00245.20 EGO60705.1 - 8.7e-69 232.5 0.0 2.5e-68 231.0 0.0 1.6 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 EGO60705.1 - 4.4e-07 29.6 0.2 1.3e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 EGO60705.1 - 0.00025 20.8 0.3 0.00025 20.8 0.3 1.8 2 1 1 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EGO60705.1 - 0.0072 15.0 0.2 0.01 14.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 EGO60705.1 - 0.056 12.8 0.3 0.13 11.6 0.3 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily HHH_3 PF12836.7 EGO60705.1 - 0.14 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif CutC PF03932.14 EGO60707.1 - 9.1e-11 41.6 0.0 7.1e-10 38.7 0.0 2.2 1 1 0 1 1 1 1 CutC family PGP_phosphatase PF09419.10 EGO60709.1 - 3.4e-70 235.0 0.0 4e-70 234.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EGO60709.1 - 1.7e-05 24.8 0.0 2.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like ORC2 PF04084.14 EGO60710.1 - 1.1e-117 392.7 0.0 1.4e-117 392.3 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DEAD PF00270.29 EGO60711.1 - 2.8e-49 167.2 0.0 9.5e-49 165.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO60711.1 - 2.9e-33 114.5 0.0 8e-33 113.1 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO60711.1 - 0.0044 17.0 0.0 0.0079 16.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGO60711.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 EGO60711.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Proteasome PF00227.26 EGO60712.1 - 1.4e-38 132.3 0.0 1.7e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sigma54_AID PF00309.20 EGO60712.1 - 0.094 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) GluRS_N PF18466.1 EGO60712.1 - 0.37 11.2 2.3 0.51 10.8 0.7 2.0 2 0 0 2 2 2 0 Glutamate--tRNA ligase N-terminal domain WD40 PF00400.32 EGO60713.1 - 3.6e-17 62.4 4.6 3.3e-05 24.6 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO60713.1 - 0.014 15.7 0.0 0.13 12.6 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO60713.1 - 0.023 13.4 0.0 0.2 10.3 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF2285 PF10074.9 EGO60713.1 - 0.043 14.5 1.2 0.17 12.6 1.2 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) Peptidase_C48 PF02902.19 EGO60714.1 - 8.5e-32 110.7 1.2 1.2e-30 107.0 0.0 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain DUF1115 PF06544.12 EGO60715.1 - 0.018 15.1 0.5 0.64 10.1 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1115) DNA_ligase_A_N PF04675.14 EGO60716.1 - 3.5e-17 63.3 0.0 6.5e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 EGO60716.1 - 7.7e-16 58.3 0.3 1.1e-13 51.4 0.3 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain PNKP_ligase PF16542.5 EGO60716.1 - 0.019 14.5 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain DIOX_N PF14226.6 EGO60717.1 - 1.7e-24 86.8 0.1 2.5e-24 86.3 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGO60717.1 - 1.4e-14 54.4 0.0 3.2e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sec39 PF08314.11 EGO60719.1 - 1.2e-280 933.4 1.9 1.4e-280 933.1 1.9 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DDHD PF02862.17 EGO60719.1 - 1 9.5 3.4 9.3 6.3 3.6 2.3 1 1 0 1 1 1 0 DDHD domain Ndufs5 PF10200.9 EGO60720.1 - 1.1e-05 25.6 0.0 1.3e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 EGO60720.1 - 0.0027 18.0 1.3 0.007 16.7 1.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.17 EGO60720.1 - 0.047 13.9 0.5 0.047 13.9 0.5 1.4 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb COX17 PF05051.13 EGO60720.1 - 0.047 14.1 0.6 0.083 13.3 0.6 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 EGO60720.1 - 0.33 11.2 2.8 0.52 10.6 2.8 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) NAD_binding_1 PF00175.21 EGO60722.1 - 2.4e-06 28.1 0.0 3.7e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGO60722.1 - 8.8e-06 25.9 0.1 0.00061 19.9 0.1 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 EGO60722.1 - 0.0066 16.8 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain SUR7 PF06687.12 EGO60723.1 - 1.6e-21 76.9 14.8 2.1e-21 76.6 14.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family MpPF26 PF07666.11 EGO60723.1 - 0.016 15.3 1.3 0.016 15.3 1.3 2.3 2 0 0 2 2 2 0 M penetrans paralogue family 26 Claudin_3 PF06653.11 EGO60723.1 - 0.019 14.9 2.6 0.019 14.9 2.6 2.6 2 1 1 3 3 3 0 Tight junction protein, Claudin-like Serinc PF03348.15 EGO60723.1 - 0.13 11.2 7.4 0.046 12.6 5.0 1.4 2 0 0 2 2 2 0 Serine incorporator (Serinc) Reticulon PF02453.17 EGO60723.1 - 0.18 11.7 8.2 0.6 10.1 5.7 2.5 2 1 0 2 2 2 0 Reticulon Claudin_2 PF13903.6 EGO60723.1 - 1.3 8.7 13.4 0.65 9.7 7.5 2.7 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF973 PF06157.11 EGO60723.1 - 3.8 6.5 9.2 0.28 10.2 2.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF973) DUF5592 PF17332.2 EGO60723.1 - 5.6 7.6 6.7 0.39 11.3 0.4 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5592) MFS_MOT1 PF16983.5 EGO60724.1 - 1.9e-55 186.0 19.2 2.4e-30 105.2 2.8 3.1 4 1 0 4 4 4 2 Molybdate transporter of MFS superfamily Xan_ur_permease PF00860.20 EGO60724.1 - 1.3e-06 27.4 12.1 9.6e-06 24.5 4.0 2.8 2 1 0 2 2 2 2 Permease family Sulfate_transp PF00916.20 EGO60724.1 - 0.0094 14.7 0.4 0.0094 14.7 0.4 3.3 3 1 0 3 3 3 1 Sulfate permease family Cytochrom_B_N_2 PF13631.6 EGO60724.1 - 0.05 13.6 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Glyco_hydro_16 PF00722.21 EGO60726.1 - 2.1e-05 24.0 0.1 6.8e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Arginase PF00491.21 EGO60730.1 - 3.7e-90 302.2 0.0 4.7e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family GST_N_3 PF13417.6 EGO60731.1 - 5.1e-08 33.2 0.3 1.1e-07 32.2 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGO60731.1 - 0.00013 22.1 0.0 0.00025 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGO60731.1 - 0.0021 18.3 0.0 0.0051 17.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO60731.1 - 0.005 16.8 0.1 0.0096 15.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aft1_HRA PF11786.8 EGO60733.1 - 2.8e-24 85.2 11.7 2.8e-24 85.2 11.7 3.0 2 0 0 2 2 2 1 Aft1 HRA domain Aft1_HRR PF11787.8 EGO60733.1 - 3.8e-24 85.7 12.1 3.8e-24 85.7 12.1 3.9 3 2 0 3 3 3 1 Aft1 HRR domain Aft1_OSA PF11785.8 EGO60733.1 - 9.2e-22 77.2 12.6 9.2e-22 77.2 12.6 4.4 4 1 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 EGO60733.1 - 8.2e-13 48.3 6.9 1.4e-12 47.5 6.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGO60733.1 - 1.5e-05 25.0 6.8 3.4e-05 23.8 6.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Activator_LAG-3 PF11498.8 EGO60733.1 - 0.00055 19.0 15.9 0.038 13.0 8.6 2.3 2 0 0 2 2 2 2 Transcriptional activator LAG-3 bZIP_Maf PF03131.17 EGO60733.1 - 0.0098 16.4 3.2 0.0098 16.4 3.2 2.4 2 0 0 2 2 2 1 bZIP Maf transcription factor MKT1_C PF12246.8 EGO60733.1 - 0.054 12.7 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication Nnf1 PF03980.14 EGO60733.1 - 0.083 13.3 3.0 0.12 12.8 0.4 2.2 2 0 0 2 2 2 0 Nnf1 MIS13 PF08202.11 EGO60735.1 - 5.5e-80 268.9 0.4 9e-80 268.2 0.0 1.5 2 0 0 2 2 2 1 Mis12-Mtw1 protein family ZapB PF06005.12 EGO60735.1 - 0.013 15.9 4.2 2.8 8.4 0.5 2.6 2 0 0 2 2 2 0 Cell division protein ZapB DUF5082 PF16888.5 EGO60735.1 - 0.022 15.0 0.3 1.6 9.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Sdh5 PF03937.16 EGO60737.1 - 3.3e-24 84.6 0.1 1.1e-23 83.0 0.1 1.8 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase EMP24_GP25L PF01105.24 EGO60738.1 - 8.5e-42 143.2 0.0 9.4e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD zf-U1 PF06220.12 EGO60739.1 - 7.6e-22 76.8 3.4 1.1e-21 76.3 3.4 1.2 1 0 0 1 1 1 1 U1 zinc finger HD PF01966.22 EGO60740.1 - 0.00013 22.2 0.6 0.00058 20.1 0.3 2.2 2 2 1 3 3 3 1 HD domain DUF218 PF02698.17 EGO60742.1 - 0.00031 20.8 0.0 0.00085 19.4 0.0 1.6 1 1 0 1 1 1 1 DUF218 domain Nudix_hydro PF18290.1 EGO60743.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Nudix hydrolase domain Mur_ligase_C PF02875.21 EGO60743.1 - 0.056 13.7 0.0 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain MGC-24 PF05283.11 EGO60744.1 - 5.5 7.4 5.4 0.92 10.0 0.3 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pkinase PF00069.25 EGO60745.1 - 1.7e-64 217.8 0.0 3.5e-64 216.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO60745.1 - 3.6e-41 141.2 0.0 6.6e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO60745.1 - 0.0001 21.2 0.2 0.00022 20.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGO60745.1 - 0.022 14.1 0.0 0.075 12.3 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Atx10homo_assoc PF09759.9 EGO60745.1 - 0.058 13.4 0.2 11 6.1 0.0 3.2 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Med15_fungi PF05397.12 EGO60745.1 - 0.15 12.3 0.3 0.45 10.8 0.3 1.7 1 0 0 1 1 1 0 Mediator complex subunit 15 Rcd1 PF04078.13 EGO60745.1 - 0.84 8.9 4.1 0.5 9.6 0.8 2.1 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like ERG4_ERG24 PF01222.17 EGO60747.1 - 7.2e-137 456.7 17.8 8.5e-137 456.4 17.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family TMEM238 PF15125.6 EGO60747.1 - 4.9 7.4 12.0 2.3 8.5 0.8 3.6 3 0 0 3 3 3 0 TMEM238 protein family ATP-synt_C PF00137.21 EGO60748.1 - 1e-34 118.6 35.4 5.1e-22 78.0 15.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Ribosomal_L7Ae PF01248.26 EGO60749.1 - 7.2e-26 89.8 0.1 9.2e-26 89.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EGO60749.1 - 1.6e-05 25.0 0.1 7.7e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 EGO60749.1 - 0.00066 19.5 0.0 0.00086 19.1 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Syja_N PF02383.18 EGO60750.1 - 2.1e-95 319.7 0.0 3.2e-95 319.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EGO60750.1 - 1.7e-41 140.5 0.0 4.5e-41 139.2 0.0 1.8 1 0 0 1 1 1 1 Inositol phosphatase Fn_bind PF02986.14 EGO60750.1 - 0.067 12.9 0.7 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 Fibronectin binding repeat Methyltransf_34 PF11312.8 EGO60751.1 - 2.8e-105 351.9 0.0 3.4e-105 351.6 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Transketolase_N PF00456.21 EGO60752.1 - 1.3e-155 517.4 0.1 1.8e-155 517.0 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EGO60752.1 - 2.1e-47 161.1 0.0 3.3e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGO60752.1 - 3.7e-13 49.5 0.0 7.1e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EGO60752.1 - 5.7e-05 22.5 0.0 0.002 17.4 0.0 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase zf-RING_13 PF17977.1 EGO60752.1 - 0.08 13.1 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ATG16 PF08614.11 EGO60753.1 - 2.8e-05 24.5 5.0 2.8e-05 24.5 5.0 6.2 4 2 1 5 5 4 2 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 EGO60753.1 - 4.2e-05 23.0 14.0 4.2e-05 23.0 14.0 3.6 1 1 1 3 3 2 1 Domain of unknown function (DUF4407) CEP63 PF17045.5 EGO60753.1 - 0.0001 22.3 5.5 0.0001 22.3 5.5 5.2 5 1 0 6 6 6 1 Centrosomal protein of 63 kDa Filament PF00038.21 EGO60753.1 - 0.00015 21.5 16.4 0.00015 21.5 16.4 5.5 4 2 2 6 6 6 2 Intermediate filament protein ADIP PF11559.8 EGO60753.1 - 0.0063 16.6 7.1 0.0063 16.6 7.1 6.2 4 2 2 6 6 6 1 Afadin- and alpha -actinin-Binding Taxilin PF09728.9 EGO60753.1 - 0.012 14.8 0.9 0.012 14.8 0.9 5.4 4 1 1 5 5 5 0 Myosin-like coiled-coil protein FlaC_arch PF05377.11 EGO60753.1 - 0.036 14.4 41.7 0.12 12.8 0.6 7.6 7 1 1 8 8 7 0 Flagella accessory protein C (FlaC) CSN7a_helixI PF18392.1 EGO60753.1 - 0.05 13.5 1.6 0.22 11.4 1.6 2.2 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain ZapB PF06005.12 EGO60753.1 - 0.088 13.3 0.5 0.088 13.3 0.5 8.7 5 1 3 8 8 8 0 Cell division protein ZapB DUF1664 PF07889.12 EGO60753.1 - 0.11 12.6 22.1 0.11 12.5 8.2 3.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EGO60753.1 - 0.94 9.5 16.4 3.7 7.6 0.3 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus EzrA PF06160.12 EGO60753.1 - 2.6 6.1 33.2 0.48 8.5 4.2 3.4 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA TSC22 PF01166.18 EGO60753.1 - 5.4 7.4 33.0 0.82 10.0 0.4 6.0 6 1 1 7 7 7 0 TSC-22/dip/bun family DUF2838 PF10998.8 EGO60756.1 - 6.9e-46 155.1 10.7 6.9e-46 155.1 10.7 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) DUF1640 PF07798.11 EGO60756.1 - 0.12 12.4 1.7 0.2 11.7 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) SMC_N PF02463.19 EGO60757.1 - 9.1e-60 201.8 0.0 7.7e-59 198.8 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGO60757.1 - 1e-25 90.3 0.0 5.3e-25 88.0 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EGO60757.1 - 3.8e-09 36.8 3.3 2.2e-05 24.4 0.4 4.3 4 2 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGO60757.1 - 5.5e-08 32.9 9.6 5.5e-08 32.9 9.6 4.4 2 2 1 4 4 3 1 AAA ATPase domain AAA_29 PF13555.6 EGO60757.1 - 5.8e-08 32.4 0.1 1.2e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 EGO60757.1 - 0.00031 19.7 124.6 0.0092 14.9 17.3 7.2 3 2 4 7 7 7 4 Spc7 kinetochore protein DUF3552 PF12072.8 EGO60757.1 - 0.0023 17.4 10.7 0.0023 17.4 10.7 8.1 4 2 4 8 8 6 2 Domain of unknown function (DUF3552) SbcCD_C PF13558.6 EGO60757.1 - 0.012 15.9 0.0 0.064 13.5 0.0 2.4 2 0 0 2 2 1 0 Putative exonuclease SbcCD, C subunit DUF4988 PF16378.5 EGO60757.1 - 0.012 15.3 4.6 0.82 9.3 0.3 3.5 2 0 0 2 2 2 0 Domain of unknown function MinE PF03776.14 EGO60757.1 - 0.036 14.1 1.5 0.3 11.1 1.5 2.7 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE ABC_tran PF00005.27 EGO60757.1 - 0.8 10.2 0.0 0.8 10.2 0.0 7.0 4 3 0 5 5 3 0 ABC transporter FtsK_alpha PF17854.1 EGO60757.1 - 1.7 8.9 8.4 1.8 8.7 0.0 4.9 3 2 0 3 3 3 0 FtsK alpha domain TFIIE_alpha PF02002.17 EGO60758.1 - 2e-15 56.5 0.0 4.1e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 EGO60758.1 - 0.086 12.4 0.5 0.67 9.5 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DNA_pol_B_thumb PF14791.6 EGO60759.1 - 9.4e-22 77.0 0.1 2.2e-21 75.8 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 EGO60759.1 - 2.8e-21 75.9 0.0 8.8e-21 74.3 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 EGO60759.1 - 1.3e-20 72.9 0.7 3.2e-20 71.7 0.7 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 EGO60759.1 - 7.4e-09 35.9 0.0 2e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 EGO60759.1 - 0.0026 18.3 0.0 0.062 13.9 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 EGO60759.1 - 0.0081 16.5 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain NTP_transf_2 PF01909.23 EGO60759.1 - 0.028 14.7 0.2 0.16 12.3 0.0 2.3 3 0 0 3 3 3 0 Nucleotidyltransferase domain MAPEG PF01124.18 EGO60760.1 - 2.5e-24 85.6 0.9 2.9e-24 85.4 0.9 1.0 1 0 0 1 1 1 1 MAPEG family Kelch_5 PF13854.6 EGO60761.1 - 2.3e-08 33.9 4.7 6.7e-08 32.4 0.1 3.4 3 0 0 3 3 3 1 Kelch motif SKG6 PF08693.10 EGO60761.1 - 3.4e-05 23.1 1.1 6e-05 22.4 1.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_2 PF07646.15 EGO60761.1 - 0.008 16.1 5.6 1.2 9.3 0.1 4.2 4 0 0 4 4 4 1 Kelch motif CD34_antigen PF06365.12 EGO60761.1 - 0.066 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Kelch_6 PF13964.6 EGO60761.1 - 0.1 13.0 4.6 1.5 9.3 0.5 3.8 4 0 0 4 4 4 0 Kelch motif Kelch_1 PF01344.25 EGO60761.1 - 0.71 9.5 4.3 34 4.1 0.1 4.0 4 0 0 4 4 4 0 Kelch motif Ndc1_Nup PF09531.10 EGO60761.1 - 0.8 8.3 4.8 1.1 7.9 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HemX PF04375.14 EGO60761.1 - 0.85 8.8 7.1 1.3 8.3 7.1 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Sec23_trunk PF04811.15 EGO60762.1 - 1.3e-79 267.2 0.0 1.8e-79 266.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EGO60762.1 - 8.3e-31 106.6 0.2 1.5e-30 105.7 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EGO60762.1 - 2.3e-25 88.4 0.1 5.8e-25 87.1 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EGO60762.1 - 9.6e-16 57.6 6.3 1.8e-15 56.7 6.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGO60762.1 - 5.3e-15 55.1 0.0 1.2e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EGO60762.1 - 0.037 13.4 0.7 0.091 12.2 0.1 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ribosomal_L11_N PF03946.14 EGO60763.1 - 7.4e-25 86.6 0.3 1.2e-24 85.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EGO60763.1 - 2.2e-14 53.7 0.0 4.1e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain ATP_bind_3 PF01171.20 EGO60763.1 - 0.052 13.3 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 PP-loop family Glyco_transf_41 PF13844.6 EGO60764.1 - 4.8e-104 348.4 0.2 1.9e-48 165.1 0.0 4.1 3 1 1 4 4 4 4 Glycosyl transferase family 41 TPR_1 PF00515.28 EGO60764.1 - 7.4e-25 85.7 1.1 0.00029 20.5 0.0 7.2 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGO60764.1 - 1.4e-19 68.5 0.3 0.0028 17.7 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGO60764.1 - 8.3e-16 56.8 0.2 0.0075 16.4 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGO60764.1 - 5.7e-15 54.7 0.4 0.014 15.1 0.0 6.3 3 2 3 6 6 6 4 TPR repeat TPR_10 PF13374.6 EGO60764.1 - 3.9e-12 45.6 5.2 0.052 13.4 0.0 6.7 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGO60764.1 - 2.2e-11 43.9 3.2 0.0012 19.1 0.3 5.2 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGO60764.1 - 4e-10 39.4 0.1 0.01 16.1 0.0 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGO60764.1 - 3.2e-09 37.2 0.1 0.017 15.6 0.0 4.3 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGO60764.1 - 5.6e-08 32.3 1.5 0.15 12.2 0.0 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGO60764.1 - 5.9e-08 32.9 1.1 2.8 9.0 0.1 6.2 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGO60764.1 - 6.3e-08 33.1 3.8 0.6 10.8 0.0 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO60764.1 - 0.00026 21.2 0.4 0.0025 18.0 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EGO60764.1 - 0.0024 17.1 0.0 2.3 7.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGO60764.1 - 0.023 14.8 0.8 2.1 8.6 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO60764.1 - 0.044 14.4 0.5 92 4.0 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TAF1_subA PF14929.6 EGO60764.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A BTAD PF03704.17 EGO60764.1 - 0.17 12.3 0.7 1.7 9.1 0.0 2.9 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Myb_DNA-binding PF00249.31 EGO60767.1 - 2.3e-27 94.9 0.8 2.5e-15 56.4 0.1 2.4 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGO60767.1 - 3.4e-19 68.8 0.1 1.6e-14 53.9 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGO60767.1 - 0.11 12.8 2.7 3.2 8.2 0.4 2.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain SHE3 PF17078.5 EGO60768.1 - 0.11 12.2 0.1 0.11 12.2 0.1 1.8 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 GvpL_GvpF PF06386.11 EGO60768.1 - 0.55 10.1 4.5 0.11 12.5 0.5 1.9 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF NCBP3 PF10309.9 EGO60769.1 - 3.2e-19 68.5 0.0 5.8e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 OEP PF02321.18 EGO60770.1 - 0.0075 16.1 4.5 0.0075 16.1 4.5 1.6 2 0 0 2 2 2 1 Outer membrane efflux protein DUF4407 PF14362.6 EGO60770.1 - 0.029 13.8 3.0 0.042 13.2 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.7 EGO60770.1 - 0.036 14.2 18.7 0.11 12.6 12.1 2.3 1 1 1 2 2 2 0 Tropomyosin like HMMR_N PF15905.5 EGO60770.1 - 0.1 12.1 10.4 0.44 10.0 10.5 1.8 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Spectrin PF00435.21 EGO60770.1 - 0.3 11.6 12.8 0.69 10.4 0.2 2.9 1 1 1 2 2 2 0 Spectrin repeat V_ATPase_I PF01496.19 EGO60770.1 - 0.47 8.3 4.5 0.68 7.8 4.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CorA PF01544.18 EGO60770.1 - 0.68 9.2 14.0 2.8 7.2 12.2 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein HAUS-augmin3 PF14932.6 EGO60770.1 - 1 8.9 9.0 1.7 8.1 9.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Nup54 PF13874.6 EGO60770.1 - 1.6 8.8 7.5 0.53 10.4 3.7 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Snapin_Pallidin PF14712.6 EGO60770.1 - 3.1 8.3 7.3 7.3 7.1 2.6 2.8 2 1 0 2 2 2 0 Snapin/Pallidin BLOC1_2 PF10046.9 EGO60770.1 - 3.3 8.1 6.2 7.2 7.0 3.2 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 EGO60770.1 - 3.8 7.6 10.1 3.6 7.6 5.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4140 PF13600.6 EGO60770.1 - 4.6 7.7 8.4 7.7 7.0 3.7 2.9 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) TolA_bind_tri PF16331.5 EGO60770.1 - 5.1 7.3 15.4 1.5 9.0 0.6 2.7 2 1 0 2 2 2 0 TolA binding protein trimerisation DUF16 PF01519.16 EGO60770.1 - 6.3 7.3 10.5 33 5.0 9.5 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Noelin-1 PF12308.8 EGO60770.1 - 6.4 6.8 7.2 6.8 6.7 0.8 3.1 1 1 2 3 3 3 0 Neurogenesis glycoprotein Uso1_p115_C PF04871.13 EGO60770.1 - 8.6 6.7 16.6 21 5.5 12.1 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 EGO60770.1 - 9.7 5.0 14.8 9.8 4.9 13.3 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Rhomboid PF01694.22 EGO60775.1 - 1.6e-39 135.3 7.6 3.4e-39 134.3 7.6 1.5 1 0 0 1 1 1 1 Rhomboid family DUF2177 PF09945.9 EGO60775.1 - 1.5 8.9 5.9 0.38 10.9 0.9 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2177) ABC2_membrane_5 PF13346.6 EGO60775.1 - 8 6.0 9.8 1.6 8.3 0.1 2.5 3 0 0 3 3 3 0 ABC-2 family transporter protein Pet127 PF08634.10 EGO60776.1 - 6.8e-120 399.6 2.3 6.8e-120 399.6 2.3 1.9 2 0 0 2 2 2 1 Mitochondrial protein Pet127 Homoserine_dh PF00742.19 EGO60776.1 - 0.17 11.8 1.1 0.36 10.7 1.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase Cohesin_load PF10345.9 EGO60777.1 - 2.7e-183 610.7 0.4 4.5e-183 609.9 0.4 1.4 1 0 0 1 1 1 1 Cohesin loading factor Abhydrolase_1 PF00561.20 EGO60778.1 - 1.2e-12 48.1 0.0 1.6e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGO60778.1 - 3.1e-06 26.7 0.0 5.5e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF5301 PF17225.3 EGO60779.1 - 0.057 13.8 1.4 0.057 13.8 1.4 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF5300) GNAT_acetyltr_2 PF13718.6 EGO60779.1 - 2.1 7.7 4.7 0.57 9.5 0.3 2.1 1 1 1 2 2 2 0 GNAT acetyltransferase 2 IGPD PF00475.18 EGO60780.1 - 1.6e-59 200.4 0.5 2.4e-59 199.7 0.5 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase N36 PF11438.8 EGO60781.1 - 0.91 9.4 3.7 16 5.5 1.5 2.5 2 0 0 2 2 2 0 36-mer N-terminal peptide of the N protein (N36) MAP65_ASE1 PF03999.12 EGO60783.1 - 0.42 9.3 9.3 0.55 8.9 9.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) NicO PF03824.16 EGO60783.1 - 0.54 9.5 1.0 0.71 9.2 0.0 1.6 2 0 0 2 2 2 0 High-affinity nickel-transport protein Roughex PF06020.11 EGO60783.1 - 0.62 9.1 5.6 1 8.4 5.6 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Sec62 PF03839.16 EGO60783.1 - 1.3 8.5 4.2 2 7.9 4.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 EphA2_TM PF14575.6 EGO60783.1 - 1.6 9.7 0.0 1.6 9.7 0.0 3.5 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DER1 PF04511.15 EGO60784.1 - 0.00042 20.3 0.1 0.00046 20.2 0.1 1.1 1 0 0 1 1 1 1 Der1-like family ArgJ PF01960.18 EGO60785.1 - 2.9e-155 516.7 0.8 3.3e-155 516.5 0.8 1.0 1 0 0 1 1 1 1 ArgJ family Rep_fac_C PF08542.11 EGO60786.1 - 6.3e-23 81.0 0.0 1.6e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EGO60786.1 - 9.6e-14 51.5 0.0 4.5e-10 39.6 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EGO60786.1 - 4.3e-12 46.6 0.0 8.6e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGO60786.1 - 7.7e-07 29.2 0.0 1.6e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO60786.1 - 6.8e-06 26.6 0.0 0.00048 20.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 EGO60786.1 - 0.00013 21.8 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EGO60786.1 - 0.00015 22.1 0.1 0.16 12.2 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.11 EGO60786.1 - 0.00024 21.0 0.0 0.00049 19.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGO60786.1 - 0.00034 20.4 0.0 0.00089 19.0 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 EGO60786.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 EGO60786.1 - 0.0031 16.9 0.0 0.037 13.4 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 EGO60786.1 - 0.0047 16.9 0.0 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 EGO60786.1 - 0.006 16.9 0.0 0.022 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA C-terminal domain DNA_pol3_gamma3 PF12169.8 EGO60786.1 - 0.0067 16.3 0.4 0.61 10.0 0.0 2.8 3 0 0 3 3 3 1 DNA polymerase III subunits gamma and tau domain III AAA_11 PF13086.6 EGO60786.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EGO60786.1 - 0.019 14.4 0.0 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein MeaB PF03308.16 EGO60786.1 - 0.023 13.7 0.0 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EGO60786.1 - 0.034 14.1 0.1 0.12 12.2 0.1 2.0 1 1 1 2 2 2 0 NTPase AAA_19 PF13245.6 EGO60786.1 - 0.051 13.9 0.1 0.14 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGO60786.1 - 0.066 12.9 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF5119 PF17145.4 EGO60786.1 - 0.082 12.8 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5119) KTI12 PF08433.10 EGO60786.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.14 EGO60786.1 - 0.13 12.3 0.2 0.65 10.0 0.1 2.3 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 EGO60786.1 - 0.14 11.9 0.1 1.9 8.2 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase DUF2075 PF09848.9 EGO60786.1 - 0.16 11.1 0.2 3.4 6.8 0.2 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CN_hydrolase PF00795.22 EGO60787.1 - 6.2e-13 48.7 0.0 4.8e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase SnoaL_4 PF13577.6 EGO60788.1 - 3.4e-08 33.7 0.0 5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain zf-BED PF02892.15 EGO60790.1 - 1.8 8.6 3.9 14 5.8 0.2 3.0 3 0 0 3 3 3 0 BED zinc finger CcmD PF04995.14 EGO60790.1 - 4.4 7.5 4.8 0.66 10.1 0.4 1.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DKCLD PF08068.12 EGO60791.1 - 4.6e-32 109.9 0.5 1.1e-30 105.5 0.4 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 EGO60791.1 - 2.3e-22 78.9 0.3 4e-22 78.1 0.3 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 EGO60791.1 - 2.1e-21 76.9 5.8 4.6e-20 72.5 0.2 3.5 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 EGO60791.1 - 3.6e-21 74.9 1.3 7.6e-21 73.9 1.3 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EGO60791.1 - 0.00017 21.8 0.0 0.00042 20.5 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain GAGA_bind PF06217.12 EGO60791.1 - 0.66 10.2 8.7 0.86 9.8 8.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family FAM199X PF15814.5 EGO60791.1 - 1 8.4 6.3 1.6 7.7 6.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X CD34_antigen PF06365.12 EGO60792.1 - 0.00061 19.4 0.2 0.0011 18.6 0.2 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Insulin_TMD PF17870.1 EGO60792.1 - 0.0025 17.9 1.3 0.0054 16.8 1.3 1.5 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Tmemb_9 PF05434.11 EGO60792.1 - 0.014 15.3 0.6 0.026 14.4 0.0 1.7 2 0 0 2 2 2 0 TMEM9 EphA2_TM PF14575.6 EGO60792.1 - 0.019 15.8 0.4 0.066 14.1 0.4 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Myc_target_1 PF15179.6 EGO60792.1 - 0.019 14.9 0.5 0.019 14.9 0.5 2.3 2 1 2 4 4 4 0 Myc target protein 1 Orf78 PF06024.12 EGO60792.1 - 0.06 13.7 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Herpes_gE PF02480.16 EGO60792.1 - 0.06 12.1 0.1 0.1 11.3 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E 7TM_GPCR_Srv PF10323.9 EGO60792.1 - 0.087 12.2 0.3 0.13 11.5 0.3 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv TMEM154 PF15102.6 EGO60792.1 - 0.089 12.7 0.2 0.29 11.0 0.2 1.8 1 0 0 1 1 1 0 TMEM154 protein family FixS PF03597.15 EGO60792.1 - 0.099 12.4 3.0 0.16 11.7 3.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Adeno_E3_CR2 PF02439.15 EGO60792.1 - 0.12 12.1 4.7 0.26 11.1 4.7 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4834 PF16118.5 EGO60792.1 - 0.16 13.0 0.0 0.52 11.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Flu_M2 PF00599.17 EGO60792.1 - 0.19 11.9 0.1 0.54 10.4 0.1 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M2) ASFV_J13L PF05568.11 EGO60792.1 - 0.21 11.3 10.2 0.23 11.2 3.7 2.8 2 1 0 2 2 2 0 African swine fever virus J13L protein SAC3_GANP PF03399.16 EGO60793.1 - 1.4e-93 313.5 2.6 2.2e-93 312.9 2.6 1.3 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EGO60793.1 - 6e-05 23.0 0.1 0.00016 21.7 0.0 1.6 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family ETC_C1_NDUFA4 PF04800.12 EGO60793.1 - 0.037 14.3 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 ETC complex I subunit conserved region F-box-like PF12937.7 EGO60794.1 - 2.2e-10 40.2 0.3 4.8e-10 39.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGO60794.1 - 1.6e-05 24.7 1.4 4.3e-05 23.3 1.4 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGO60794.1 - 0.062 13.2 1.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 F-box MFS_1 PF07690.16 EGO60795.1 - 7.8e-26 90.8 48.3 1.2e-17 63.9 29.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO60795.1 - 1.5e-21 76.8 19.8 2.9e-17 62.7 6.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Snf7 PF03357.21 EGO60797.1 - 9.2e-33 113.3 12.8 9.2e-33 113.3 12.8 2.0 2 0 0 2 2 2 1 Snf7 VirD1 PF07328.11 EGO60797.1 - 0.14 12.2 0.8 0.27 11.2 0.2 1.7 1 1 1 2 2 2 0 T-DNA border endonuclease VirD1 Allexi_40kDa PF05549.11 EGO60797.1 - 0.28 10.6 4.8 0.46 10.0 4.5 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF3138 PF11336.8 EGO60797.1 - 0.77 8.3 10.4 0.23 10.0 6.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Fmp27_WPPW PF10359.9 EGO60797.1 - 1.8 7.3 8.3 2.3 7.0 8.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ten1 PF12658.7 EGO60798.1 - 6.7e-26 90.6 0.0 8.1e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 EGO60798.1 - 0.00011 21.9 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit ICE2 PF08426.10 EGO60800.1 - 4.7e-159 529.9 9.9 5.4e-159 529.7 9.9 1.0 1 0 0 1 1 1 1 ICE2 Zw10 PF06248.13 EGO60801.1 - 1.1e-09 37.4 0.9 1.2e-08 34.1 0.9 2.1 1 1 0 1 1 1 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 EGO60801.1 - 0.00031 20.5 0.0 0.00079 19.2 0.0 1.6 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal TFR_dimer PF04253.15 EGO60801.1 - 0.061 13.4 0.2 0.35 11.0 0.2 2.4 1 1 0 1 1 1 0 Transferrin receptor-like dimerisation domain ABC_tran_CTD PF16326.5 EGO60801.1 - 6.3 7.1 6.6 7.1 7.0 0.1 3.7 3 0 0 3 3 3 0 ABC transporter C-terminal domain Peptidase_M16_C PF05193.21 EGO60802.1 - 2.2e-24 86.5 0.0 9e-19 68.2 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGO60802.1 - 5.8e-07 29.6 0.0 2.3e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 EGO60802.1 - 0.0001 21.6 4.9 0.00056 19.1 4.9 2.0 1 1 0 1 1 1 1 Peptidase M16C associated DUF4587 PF15248.6 EGO60802.1 - 0.16 12.8 0.6 0.56 11.0 0.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) Sporozoite_P67 PF05642.11 EGO60802.1 - 0.32 9.0 1.0 0.54 8.3 1.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2205 PF10224.9 EGO60802.1 - 0.82 9.7 3.1 1.9 8.5 3.1 1.6 1 0 0 1 1 1 0 Short coiled-coil protein MRP-S26 PF14943.6 EGO60802.1 - 1.7 8.6 6.6 11 5.9 2.1 2.4 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 STAG PF08514.11 EGO60803.1 - 0.0098 15.8 1.1 0.026 14.4 1.1 1.7 1 1 0 1 1 1 1 STAG domain Acetyltransf_1 PF00583.25 EGO60804.1 - 1.9e-14 53.9 0.0 2.7e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO60804.1 - 4.3e-11 42.9 0.0 7.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO60804.1 - 1.7e-10 41.2 0.0 2.4e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO60804.1 - 1.7e-06 27.9 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGO60804.1 - 4e-05 23.7 0.0 5.1e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGO60804.1 - 0.00028 21.1 0.1 0.0007 19.8 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain NMO PF03060.15 EGO60805.1 - 7.2e-52 176.8 3.1 1.2e-51 176.1 3.1 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGO60805.1 - 1.8e-08 33.8 1.1 4.2e-07 29.3 1.1 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGO60805.1 - 0.022 13.8 3.0 0.039 13.0 3.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF1729 PF08354.10 EGO60805.1 - 0.1 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Taxilin PF09728.9 EGO60807.1 - 6.9e-95 317.8 64.1 1.1e-94 317.1 64.1 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein TMF_TATA_bd PF12325.8 EGO60807.1 - 0.0059 16.8 58.1 0.77 10.0 8.4 4.8 2 2 2 4 4 4 3 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 EGO60807.1 - 0.043 13.9 61.9 0.43 10.7 8.2 4.5 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein DUF948 PF06103.11 EGO60807.1 - 1 9.7 18.4 1.8 8.9 0.3 4.2 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 EGO60807.1 - 7.6 6.6 37.3 2.5 8.1 5.4 4.1 2 2 2 4 4 4 0 Laminin Domain II ATG16 PF08614.11 EGO60807.1 - 7.7 6.7 51.8 4.6 7.4 24.1 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) M16C_assoc PF08367.11 EGO60808.1 - 5.4e-84 281.2 0.2 8.2e-84 280.6 0.2 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EGO60808.1 - 2.4e-30 105.9 0.0 3.5e-21 76.0 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGO60808.1 - 0.0038 17.2 0.1 0.2 11.6 0.0 2.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Orn_Arg_deC_N PF02784.16 EGO60809.1 - 1.5e-88 296.3 0.0 2.1e-88 295.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EGO60809.1 - 2.3e-20 72.7 0.0 3.7e-20 72.0 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Pribosyl_synth PF14572.6 EGO60810.1 - 5.2e-34 117.9 2.3 2.9e-22 79.6 0.6 3.2 2 1 1 3 3 3 3 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EGO60810.1 - 3.5e-29 101.1 0.0 1.1e-28 99.5 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EGO60810.1 - 6e-17 61.6 0.2 1.2e-16 60.6 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGO60810.1 - 0.041 13.3 0.1 0.066 12.6 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase WD40 PF00400.32 EGO60811.1 - 3.3e-21 75.2 15.0 0.00018 22.2 0.3 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO60811.1 - 1.9e-13 50.5 5.8 3.6e-05 24.0 0.4 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGO60811.1 - 7.9e-07 29.1 0.1 0.004 17.1 0.1 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGO60811.1 - 0.084 11.8 0.2 1.1 8.1 0.0 2.3 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein UQ_con PF00179.26 EGO60812.1 - 1.4e-19 70.2 0.0 2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PRIMA1 PF16101.5 EGO60812.1 - 1.5 8.8 7.5 0.57 10.2 1.4 2.3 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 DHHC PF01529.20 EGO60813.1 - 8.8e-38 129.4 9.1 8.8e-38 129.4 9.1 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4064 PF13273.6 EGO60813.1 - 0.019 15.2 0.0 0.36 11.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) STELLO PF03385.17 EGO60813.1 - 0.071 11.9 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 STELLO glycosyltransferases PI-PLC-X PF00388.19 EGO60814.1 - 1.9e-57 192.9 0.0 3.8e-57 192.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGO60814.1 - 1.3e-42 144.8 0.0 3.7e-42 143.3 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EGO60814.1 - 7.8e-05 22.9 0.0 0.00018 21.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 EGO60814.1 - 0.0059 17.1 0.1 0.013 15.9 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PH PF00169.29 EGO60814.1 - 0.012 16.1 0.2 0.031 14.8 0.2 1.7 1 0 0 1 1 1 0 PH domain PH_12 PF16457.5 EGO60814.1 - 0.013 16.0 0.1 0.041 14.4 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain PH_8 PF15409.6 EGO60814.1 - 0.013 15.7 0.2 0.13 12.6 0.0 2.5 3 0 0 3 3 3 0 Pleckstrin homology domain Prok-JAB PF14464.6 EGO60814.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain DXPR_C PF13288.6 EGO60814.1 - 0.14 12.4 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 DXP reductoisomerase C-terminal domain NdhM PF10664.9 EGO60814.1 - 0.17 12.2 0.2 0.91 9.8 0.1 2.2 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M RVT_1 PF00078.27 EGO60818.1 - 0.025 14.1 0.3 0.025 14.1 0.3 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ARL2_Bind_BART PF11527.8 EGO60818.1 - 0.051 13.7 1.6 0.059 13.5 1.6 1.2 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART BP28CT PF08146.12 EGO60819.1 - 0.013 15.4 0.1 0.014 15.2 0.1 1.1 1 0 0 1 1 1 0 BP28CT (NUC211) domain B-block_TFIIIC PF04182.12 EGO60824.1 - 9.5e-16 57.7 0.0 2.4e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC Cyanate_lyase PF02560.14 EGO60826.1 - 2.2e-31 107.5 0.0 3.2e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 EGO60826.1 - 0.00029 21.1 0.0 0.00043 20.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EGO60826.1 - 0.00038 20.1 0.0 0.00098 18.7 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 EGO60826.1 - 0.034 13.9 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 EGO60826.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r4 PF04545.16 EGO60826.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 Ebp2 PF05890.12 EGO60827.1 - 4.4e-89 298.6 15.7 4.4e-89 298.6 15.7 2.0 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 STAT_bind PF02864.15 EGO60827.1 - 0.13 12.8 1.4 0.31 11.6 1.4 1.6 1 0 0 1 1 1 0 STAT protein, DNA binding domain GATase_4 PF13230.6 EGO60829.1 - 1.1e-16 60.6 0.0 6.3e-14 51.5 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 EGO60829.1 - 1.9e-08 34.5 0.0 4.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Dynamin_N PF00350.23 EGO60830.1 - 3.8e-44 150.7 0.0 7.7e-44 149.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EGO60830.1 - 7.9e-12 45.0 0.2 1.9e-11 43.8 0.1 1.6 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EGO60830.1 - 4.5e-05 23.5 0.0 0.00017 21.6 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGO60830.1 - 0.0085 16.5 0.3 0.074 13.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EGO60830.1 - 0.041 13.7 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGO60830.1 - 0.089 12.5 0.6 0.17 11.5 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain STAT_int PF02865.17 EGO60830.1 - 0.15 12.5 0.9 1.5 9.3 0.3 2.7 3 0 0 3 3 3 0 STAT protein, protein interaction domain Cation_efflux PF01545.21 EGO60831.1 - 1.9e-09 37.6 10.3 7.2e-09 35.7 10.3 1.8 1 1 0 1 1 1 1 Cation efflux family PIG-Y PF15159.6 EGO60832.1 - 2.7e-21 76.3 11.4 4.3e-21 75.6 11.4 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y zf-MYND PF01753.18 EGO60833.1 - 1.1e-07 31.8 20.6 2.6e-07 30.6 20.6 1.7 1 0 0 1 1 1 1 MYND finger zf-TAZ PF02135.16 EGO60833.1 - 2.1 8.9 11.3 0.67 10.5 8.3 1.7 2 0 0 2 2 2 0 TAZ zinc finger PQ-loop PF04193.14 EGO60835.1 - 1.7e-28 98.1 20.0 1.9e-15 56.4 0.6 2.8 3 0 0 3 3 3 2 PQ loop repeat Arm PF00514.23 EGO60836.1 - 6.2e-96 311.9 15.8 3.6e-13 49.0 0.3 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EGO60836.1 - 3.1e-27 94.8 0.8 7.9e-27 93.5 0.8 1.7 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 EGO60836.1 - 2.1e-23 81.6 4.6 3.2e-23 81.0 3.4 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 EGO60836.1 - 4.2e-23 81.4 7.3 5.6e-09 36.3 0.1 6.3 5 1 1 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 EGO60836.1 - 3.9e-20 72.0 0.2 1.5e-08 34.9 0.0 5.3 1 1 4 5 5 5 3 HEAT repeats HEAT PF02985.22 EGO60836.1 - 5.3e-20 69.8 2.7 1.1e-05 25.2 0.0 7.4 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 EGO60836.1 - 2.5e-07 30.4 0.0 0.03 13.8 0.0 3.9 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 EGO60836.1 - 3.6e-05 22.5 0.0 0.0045 15.6 0.0 2.5 1 1 0 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 EGO60836.1 - 8.4e-05 22.7 0.0 1.7 8.8 0.0 4.5 3 2 2 5 5 5 2 V-ATPase subunit H HEAT_PBS PF03130.16 EGO60836.1 - 0.00038 20.9 0.2 0.8 10.6 0.0 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 EGO60836.1 - 0.0026 17.8 0.0 2 8.4 0.0 2.7 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 NopRA1 PF16201.5 EGO60836.1 - 0.026 14.1 0.0 9.1 5.8 0.0 3.8 2 2 2 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 EGO60836.1 - 0.041 14.1 4.8 5.3 7.4 0.1 4.6 3 2 3 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 POT1PC PF16686.5 EGO60837.1 - 3.9e-50 169.7 0.6 8.8e-50 168.6 0.0 2.0 3 0 0 3 3 3 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 EGO60837.1 - 3.2e-25 88.6 0.0 6.4e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 EGO60837.1 - 0.00023 21.1 0.1 0.11 12.5 0.0 3.3 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain REPA_OB_2 PF16900.5 EGO60837.1 - 0.00056 19.8 0.1 0.0024 17.7 0.0 2.1 2 0 0 2 2 2 1 Replication protein A OB domain PHD20L1_u1 PF16660.5 EGO60837.1 - 0.078 13.7 1.1 0.56 11.0 0.0 2.8 3 0 0 3 3 3 0 PHD finger protein 20-like protein 1 DUF4407 PF14362.6 EGO60837.1 - 1.1 8.5 12.3 0.29 10.5 7.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) UreD PF01774.17 EGO60838.1 - 5.9e-79 264.9 0.7 1.4e-77 260.4 0.2 2.2 2 0 0 2 2 2 1 UreD urease accessory protein STAG PF08514.11 EGO60838.1 - 7.3e-33 112.9 0.0 2.2e-32 111.3 0.0 1.9 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.6 EGO60838.1 - 1e-05 25.8 0.0 0.023 15.1 0.0 3.9 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.22 EGO60838.1 - 0.011 15.9 1.7 27 5.4 0.0 5.6 6 0 0 6 6 6 0 HEAT repeat Nucleo_P87 PF07267.11 EGO60838.1 - 9.1 5.0 16.2 0.14 11.0 6.7 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 RNA_pol_Rpc4 PF05132.14 EGO60839.1 - 4.8e-28 98.5 0.2 4.8e-28 98.5 0.2 3.4 3 1 0 3 3 3 1 RNA polymerase III RPC4 DUF3959 PF13105.6 EGO60839.1 - 0.82 9.1 2.3 0.96 8.9 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) DUF737 PF05300.11 EGO60839.1 - 2.3 8.5 13.0 3.6 7.9 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF737) API5 PF05918.11 EGO60839.1 - 6.1 5.5 12.7 0.18 10.6 6.4 1.6 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Med3 PF11593.8 EGO60839.1 - 7.4 5.7 18.4 17 4.5 14.3 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal COPI_assoc PF08507.10 EGO60840.1 - 5.2 7.1 8.5 11 6.1 8.5 1.6 1 1 0 1 1 1 0 COPI associated protein Zn_clus PF00172.18 EGO60841.1 - 0.00061 19.8 12.5 0.0013 18.8 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 EGO60841.1 - 0.0078 15.7 0.0 0.024 14.1 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone domain CHZ YL1 PF05764.13 EGO60841.1 - 9.3 6.3 8.1 0.91 9.6 3.3 1.7 2 0 0 2 2 2 0 YL1 nuclear protein Cyclin_N PF00134.23 EGO60842.1 - 2.6e-44 150.0 0.3 5.5e-44 149.0 0.3 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGO60842.1 - 2.2e-33 114.9 0.3 1e-32 112.7 0.0 2.4 3 0 0 3 3 3 1 Cyclin, C-terminal domain UPF0258 PF06789.12 EGO60842.1 - 0.15 12.2 1.3 12 6.0 0.3 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) Mito_carr PF00153.27 EGO60843.1 - 6.3e-73 240.8 0.2 7.4e-26 89.9 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EGO60843.1 - 2.5e-14 53.4 4.3 2.8e-08 34.1 0.3 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EGO60843.1 - 1.8e-12 46.1 2.8 1.2e-05 24.8 0.2 5.8 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 EGO60843.1 - 2.5e-11 42.3 6.7 6e-06 25.4 0.4 5.5 7 0 0 7 7 7 3 EF hand EF-hand_8 PF13833.6 EGO60843.1 - 4.8e-08 32.7 2.2 0.27 11.1 0.0 5.4 5 1 0 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 EGO60843.1 - 2.3e-07 30.0 0.9 0.00027 20.3 0.7 3.1 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EGO60843.1 - 0.022 15.1 0.0 81 3.6 0.0 4.0 4 0 0 4 4 4 0 EF-hand domain DUF1688 PF07958.11 EGO60844.1 - 2.8e-182 606.1 0.0 3.2e-182 605.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) PLU-1 PF08429.11 EGO60845.1 - 2.4e-107 359.0 16.8 2e-104 349.4 16.2 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 EGO60845.1 - 7.7e-44 148.8 0.2 1.7e-43 147.7 0.2 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 EGO60845.1 - 4.2e-21 75.4 0.0 1.1e-20 74.1 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 EGO60845.1 - 1.6e-16 59.9 34.8 7.4e-09 35.4 11.2 3.7 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 EGO60845.1 - 2.5e-12 46.5 3.7 6e-12 45.3 3.7 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 EGO60845.1 - 2.3e-11 43.9 7.4 2.3e-11 43.9 7.4 2.2 2 0 0 2 2 2 1 C5HC2 zinc finger C1_1 PF00130.22 EGO60845.1 - 0.0092 15.8 15.7 0.17 11.8 3.1 2.8 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 EGO60845.1 - 1.4 9.1 25.7 1.4 9.1 6.0 2.9 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.6 EGO60845.1 - 2.6 7.6 13.3 7.9 6.1 4.9 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 EGO60845.1 - 3.2 7.4 17.2 0.22 11.1 5.8 2.7 2 0 0 2 2 2 0 PHD-finger GIY-YIG PF01541.24 EGO60847.1 - 9.9e-12 45.0 0.0 3e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 GIY-YIG catalytic domain PHD_Oberon PF07227.11 EGO60847.1 - 0.018 14.9 1.6 0.028 14.3 1.6 1.2 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein zf-HC5HC2H PF13771.6 EGO60847.1 - 0.024 14.9 2.8 0.046 14.0 2.8 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EGO60847.1 - 0.035 14.3 2.2 0.061 13.5 2.2 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.11 EGO60847.1 - 0.36 11.2 6.9 0.16 12.3 3.5 2.0 2 0 0 2 2 2 0 RING-like domain FANCL_C PF11793.8 EGO60847.1 - 0.44 10.8 2.8 0.97 9.7 2.8 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 EGO60847.1 - 0.47 10.4 5.5 0.23 11.4 2.1 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF3449 PF11931.8 EGO60848.1 - 4.4e-76 254.8 1.8 4.3e-75 251.5 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EGO60848.1 - 1.8e-26 92.5 1.4 1.8e-26 92.5 1.4 1.8 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EGO60848.1 - 5e-13 48.7 0.3 1.3e-12 47.4 0.3 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 EGO60848.1 - 6.2e-11 42.3 3.3 1.5e-08 34.7 0.7 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGO60848.1 - 3.5e-09 36.8 1.3 4.6e-07 30.0 0.7 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGO60848.1 - 0.00069 19.9 0.1 0.19 12.0 0.1 3.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) BIR PF00653.21 EGO60848.1 - 0.0038 17.8 0.3 0.011 16.4 0.3 1.8 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain zf-DBF PF07535.12 EGO60848.1 - 0.015 15.4 0.3 0.015 15.4 0.3 2.9 3 1 0 3 3 3 0 DBF zinc finger zf-C2H2_4 PF13894.6 EGO60848.1 - 0.052 14.4 1.1 14 6.8 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2175 PF09943.9 EGO60848.1 - 0.19 12.0 0.9 20 5.5 0.4 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) DEAD PF00270.29 EGO60849.1 - 6.1e-43 146.6 0.2 1e-42 145.9 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO60849.1 - 2.6e-33 114.7 0.0 9.6e-33 112.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EGO60849.1 - 0.00043 20.0 0.1 0.00065 19.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EGO60849.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGO60849.1 - 0.0016 18.8 0.1 0.012 16.0 0.1 2.1 2 0 0 2 2 2 1 AAA domain DUF5393 PF17371.2 EGO60849.1 - 0.053 11.7 0.1 0.083 11.0 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) Flavi_DEAD PF07652.14 EGO60849.1 - 0.057 13.4 0.2 0.19 11.7 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 EGO60849.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 EGO60849.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 EGO60849.1 - 0.15 12.4 0.9 0.67 10.2 0.9 2.0 1 1 0 1 1 1 0 AAA domain Aldo_ket_red PF00248.21 EGO60850.1 - 5.1e-38 130.9 0.0 6.9e-36 123.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 EGO60851.1 - 1.1e-34 119.9 41.0 2.5e-31 108.9 23.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO60851.1 - 6.4e-32 111.0 22.0 7.2e-31 107.5 22.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_A8 PF01252.18 EGO60851.1 - 2.1 8.6 6.5 0.39 10.9 1.6 2.4 2 1 0 2 2 2 0 Signal peptidase (SPase) II Arylesterase PF01731.20 EGO60852.1 - 0.026 14.7 0.0 0.098 12.9 0.0 2.2 2 1 0 2 2 2 0 Arylesterase Radical_SAM_C PF16199.5 EGO60853.1 - 9.5e-32 108.9 0.0 1.8e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EGO60853.1 - 8.1e-18 65.4 0.1 2.7e-17 63.7 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EGO60853.1 - 3.4e-09 37.0 0.1 8.1e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGO60853.1 - 4.2e-06 26.7 0.0 1.1e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO60853.1 - 0.026 14.9 0.0 0.061 13.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_binding PF02629.19 EGO60854.1 - 3e-26 91.9 0.3 3e-26 91.9 0.3 2.2 2 1 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EGO60854.1 - 6.1e-23 81.3 0.5 1.5e-22 80.1 0.3 1.7 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 EGO60854.1 - 9.6e-08 31.9 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EGO60854.1 - 0.0024 18.3 0.0 0.0093 16.5 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain UQ_con PF00179.26 EGO60855.1 - 2.6e-41 140.6 0.0 3.3e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EGO60855.1 - 7.6e-07 28.9 0.2 1.4e-06 28.0 0.2 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 EGO60855.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGO60855.1 - 0.024 14.5 0.1 0.035 14.0 0.1 1.3 1 0 0 1 1 1 0 UEV domain Creb_binding PF09030.10 EGO60855.1 - 0.1 13.3 0.0 0.15 12.8 0.0 1.2 1 0 0 1 1 1 0 Creb binding AAA PF00004.29 EGO60856.1 - 5.8e-41 140.0 0.0 1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGO60856.1 - 9.1e-11 41.4 0.9 1.7e-10 40.5 0.9 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EGO60856.1 - 1.8e-10 40.6 0.3 3.8e-10 39.6 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EGO60856.1 - 5e-06 26.8 0.2 0.0061 16.8 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EGO60856.1 - 7.1e-06 26.2 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EGO60856.1 - 1.1e-05 24.7 0.0 2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EGO60856.1 - 5.4e-05 23.2 0.1 0.00018 21.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGO60856.1 - 0.00025 21.5 0.3 0.0027 18.1 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGO60856.1 - 0.00033 20.4 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 EGO60856.1 - 0.001 18.6 0.7 0.0062 16.2 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 EGO60856.1 - 0.0013 18.9 0.0 0.026 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGO60856.1 - 0.0021 18.6 0.2 0.0047 17.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 EGO60856.1 - 0.0022 18.2 0.2 0.0083 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGO60856.1 - 0.017 15.1 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGO60856.1 - 0.018 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 EGO60856.1 - 0.019 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EGO60856.1 - 0.026 14.4 0.2 0.64 9.9 0.1 2.5 2 1 0 3 3 2 0 NACHT domain TIP49 PF06068.13 EGO60856.1 - 0.027 13.7 0.9 0.07 12.3 0.1 1.9 2 1 0 2 2 2 0 TIP49 P-loop domain ATPase PF06745.13 EGO60856.1 - 0.027 13.8 0.2 0.51 9.6 0.1 2.2 1 1 0 2 2 2 0 KaiC RNA_helicase PF00910.22 EGO60856.1 - 0.054 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EGO60856.1 - 0.06 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 EGO60856.1 - 0.061 12.8 1.7 0.51 9.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 EGO60856.1 - 0.07 12.4 0.0 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 EGO60856.1 - 0.077 12.6 1.4 0.6 9.6 0.4 2.5 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 EGO60856.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 EGO60856.1 - 0.18 11.3 0.1 0.52 9.8 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGO60856.1 - 0.23 11.1 1.7 0.29 10.8 0.3 2.0 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGO60856.1 - 0.3 11.6 1.4 1 9.9 0.4 2.6 2 1 0 2 2 1 0 ABC transporter Ribosomal_L13 PF00572.18 EGO60857.1 - 8.5e-12 45.4 0.0 8.2e-10 39.0 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 BAG PF02179.16 EGO60858.1 - 2.4e-19 69.5 0.1 4.9e-19 68.5 0.1 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 EGO60858.1 - 2.5e-05 24.0 0.0 4.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EGO60858.1 - 0.0086 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EGO60858.1 - 0.045 13.8 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Glutaredoxin PF00462.24 EGO60859.1 - 2.2e-21 75.8 0.0 4.3e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 EGO60859.1 - 0.0035 17.2 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 EGO60859.1 - 0.0039 17.6 0.1 0.0082 16.6 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.20 EGO60859.1 - 0.018 14.9 0.4 0.34 10.7 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF836 PF05768.14 EGO60859.1 - 0.027 14.9 0.1 0.037 14.4 0.1 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 EGO60859.1 - 0.028 14.8 0.0 0.045 14.2 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.6 EGO60859.1 - 0.04 13.7 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 EGO60859.1 - 0.064 13.4 0.3 1.9 8.6 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin Redoxin PF08534.10 EGO60859.1 - 0.087 12.5 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Redoxin GST_N_2 PF13409.6 EGO60859.1 - 0.19 12.0 0.0 0.25 11.7 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Chalcone_2 PF16035.5 EGO60860.1 - 9e-76 254.2 0.0 1.3e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 EGO60860.1 - 0.0023 18.1 0.1 0.024 14.7 0.0 2.3 2 1 0 2 2 2 1 Chalcone isomerase-like LRR_6 PF13516.6 EGO60862.1 - 4.8e-14 51.1 16.1 2.6 8.3 0.0 12.3 13 0 0 13 13 13 3 Leucine Rich repeat F-box-like PF12937.7 EGO60862.1 - 8.9e-11 41.5 3.4 1.6e-10 40.7 0.7 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EGO60862.1 - 9.7e-10 38.6 11.2 2.8 8.5 0.2 7.6 4 2 2 8 8 8 4 Leucine Rich repeats (2 copies) F-box PF00646.33 EGO60862.1 - 0.00015 21.5 1.7 0.00026 20.8 0.2 2.3 2 0 0 2 2 2 1 F-box domain DUF1699 PF08004.11 EGO60862.1 - 0.0097 15.6 0.6 4.5 6.9 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1699) LRR_1 PF00560.33 EGO60862.1 - 1.7 9.5 14.1 31 5.7 0.0 7.4 8 0 0 8 8 8 0 Leucine Rich Repeat 4HBT PF03061.22 EGO60864.1 - 6.2e-11 42.5 0.1 1.4e-10 41.4 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Sod_Fe_C PF02777.18 EGO60866.1 - 9.7e-37 125.2 0.8 1.5e-36 124.6 0.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGO60866.1 - 1.8e-32 111.6 5.4 1.8e-32 111.6 3.2 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain T5orf172 PF10544.9 EGO60868.1 - 1.3e-26 93.2 0.7 5.7e-26 91.0 0.4 2.3 1 1 1 2 2 2 1 T5orf172 domain MUG113 PF13455.6 EGO60868.1 - 6.6e-25 87.6 0.6 1.4e-24 86.6 0.2 1.7 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 Alb1 PF09135.11 EGO60868.1 - 0.062 14.2 0.9 0.25 12.3 0.3 2.3 2 0 0 2 2 2 0 Alb1 Chorismate_bind PF00425.18 EGO60869.1 - 1.4e-70 237.8 0.0 2.3e-70 237.1 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EGO60869.1 - 1e-29 103.7 0.0 1.8e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EGO60869.1 - 6.8e-17 62.0 0.0 1.3e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EGO60869.1 - 0.0054 16.5 2.1 0.091 12.5 0.8 2.9 2 1 0 2 2 2 1 Peptidase C26 DUF2911 PF11138.8 EGO60869.1 - 0.093 12.6 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) Zn_clus PF00172.18 EGO60870.1 - 1.3e-06 28.4 8.1 2.6e-06 27.4 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4048 PF13257.6 EGO60871.1 - 3.6e-10 40.1 6.7 3.6e-10 40.1 6.7 4.1 3 2 1 4 4 4 2 Domain of unknown function (DUF4048) UPF0561 PF10573.9 EGO60871.1 - 0.092 12.9 0.6 0.3 11.2 0.6 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Bap31_Bap29_C PF18035.1 EGO60871.1 - 0.16 12.0 0.3 0.31 11.1 0.3 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain ATP-synt_ab PF00006.25 EGO60872.1 - 1e-109 365.2 0.0 1.4e-109 364.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EGO60872.1 - 2e-48 163.2 0.5 4.9e-48 162.0 0.1 1.9 2 0 0 2 2 2 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EGO60872.1 - 9.4e-16 58.1 4.7 2.6e-15 56.7 4.7 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF4061 PF13270.6 EGO60872.1 - 0.25 11.7 1.0 0.77 10.1 1.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) N-SET PF11764.8 EGO60873.1 - 2.4e-50 171.0 0.2 2.4e-50 171.0 0.2 3.0 4 0 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 EGO60873.1 - 2.1e-27 94.6 2.7 2.1e-27 94.5 1.0 2.0 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated SET PF00856.28 EGO60873.1 - 8.4e-20 71.8 0.2 8.4e-20 71.8 0.2 3.2 4 2 0 4 4 4 1 SET domain RRM_1 PF00076.22 EGO60873.1 - 0.071 12.9 0.0 0.73 9.7 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DIX PF00778.17 EGO60874.1 - 0.086 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 DIX domain Tropomyosin_1 PF12718.7 EGO60875.1 - 6.2e-56 188.5 34.3 7.2e-56 188.3 34.3 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EGO60875.1 - 4.2e-08 32.9 33.3 7e-05 22.3 18.9 2.7 1 1 1 2 2 2 2 Tropomyosin DUF724 PF05266.14 EGO60875.1 - 0.00012 22.0 25.9 0.02 14.7 10.1 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF724) Spc7 PF08317.11 EGO60875.1 - 0.00016 20.7 34.0 0.01 14.7 12.9 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 EGO60875.1 - 0.00054 20.2 27.4 0.21 11.8 18.7 2.4 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 EGO60875.1 - 0.00069 19.6 34.7 0.012 15.7 5.0 2.5 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.6 EGO60875.1 - 0.00087 19.7 32.4 0.043 14.2 12.2 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4200) TACC_C PF05010.14 EGO60875.1 - 0.0011 18.8 26.6 0.054 13.3 14.5 2.4 1 1 1 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ATG16 PF08614.11 EGO60875.1 - 0.0013 19.0 32.3 0.097 12.9 6.5 2.4 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) CENP-K PF11802.8 EGO60875.1 - 0.0018 17.9 21.5 0.33 10.5 5.1 2.1 1 1 1 2 2 2 2 Centromere-associated protein K HOOK PF05622.12 EGO60875.1 - 0.0023 16.2 28.0 0.0031 15.7 28.0 1.2 1 0 0 1 1 1 1 HOOK protein Laminin_II PF06009.12 EGO60875.1 - 0.0025 17.8 20.7 0.013 15.5 4.8 2.3 1 1 1 2 2 2 1 Laminin Domain II GAS PF13851.6 EGO60875.1 - 0.0037 16.7 32.4 0.15 11.4 22.1 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 EGO60875.1 - 0.004 17.4 19.9 0.004 17.4 19.9 2.1 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 Fez1 PF06818.15 EGO60875.1 - 0.0064 17.0 26.8 0.0097 16.4 26.8 1.3 1 0 0 1 1 1 1 Fez1 Atg14 PF10186.9 EGO60875.1 - 0.0088 15.2 10.1 0.0088 15.2 10.1 2.1 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 HAP1_N PF04849.13 EGO60875.1 - 0.0094 15.2 29.8 0.012 14.9 29.8 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region HMMR_C PF15908.5 EGO60875.1 - 0.014 15.7 19.4 0.11 12.7 4.4 2.9 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal bZIP_1 PF00170.21 EGO60875.1 - 0.015 15.4 31.1 0.58 10.3 2.0 4.8 3 2 2 5 5 5 0 bZIP transcription factor KLRAQ PF10205.9 EGO60875.1 - 0.015 15.5 23.6 0.034 14.4 9.7 3.0 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein DUF1664 PF07889.12 EGO60875.1 - 0.017 15.2 17.7 0.033 14.2 2.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ERM PF00769.19 EGO60875.1 - 0.018 14.8 37.1 0.51 10.1 27.2 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Cortex-I_coil PF09304.10 EGO60875.1 - 0.022 15.0 23.0 1.6 9.0 0.2 3.4 2 1 1 3 3 3 0 Cortexillin I, coiled coil TMF_DNA_bd PF12329.8 EGO60875.1 - 0.022 14.7 16.2 0.022 14.7 16.2 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding EzrA PF06160.12 EGO60875.1 - 0.022 12.9 25.3 0.065 11.4 6.5 2.0 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA T3SSipB PF16535.5 EGO60875.1 - 0.023 15.2 18.1 3.3 8.2 0.2 3.0 1 1 2 3 3 3 0 Type III cell invasion protein SipB Taxilin PF09728.9 EGO60875.1 - 0.023 13.9 30.9 0.2 10.8 10.7 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Alanine_zipper PF11839.8 EGO60875.1 - 0.024 15.0 11.7 0.26 11.7 1.8 3.6 2 1 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein FlaC_arch PF05377.11 EGO60875.1 - 0.032 14.6 24.3 1.4 9.4 0.2 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 EGO60875.1 - 0.033 14.4 23.7 0.72 10.1 2.8 4.1 3 1 1 4 4 4 0 Haemolysin XhlA DUF3450 PF11932.8 EGO60875.1 - 0.034 13.4 28.7 0.22 10.8 13.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BRE1 PF08647.11 EGO60875.1 - 0.039 14.0 32.1 0.32 11.1 17.6 2.4 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Uso1_p115_C PF04871.13 EGO60875.1 - 0.041 14.2 36.0 0.54 10.6 16.6 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ADIP PF11559.8 EGO60875.1 - 0.042 13.9 31.4 0.1 12.7 11.0 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding SOGA PF11365.8 EGO60875.1 - 0.049 14.8 23.6 1.2 10.3 11.9 3.5 1 1 2 3 3 3 0 Protein SOGA DUF5082 PF16888.5 EGO60875.1 - 0.05 13.9 21.5 2.5 8.4 0.9 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 EGO60875.1 - 0.085 13.4 39.7 0.75 10.3 15.4 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region NPV_P10 PF05531.12 EGO60875.1 - 0.088 13.3 11.0 19 5.8 0.1 3.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein KxDL PF10241.9 EGO60875.1 - 0.091 13.1 0.6 0.091 13.1 0.6 3.8 1 1 3 4 4 4 0 Uncharacterized conserved protein Syntaxin-6_N PF09177.11 EGO60875.1 - 0.098 13.2 21.5 1.1 9.9 6.8 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CALCOCO1 PF07888.11 EGO60875.1 - 0.11 11.3 31.6 0.8 8.5 10.1 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like HMMR_N PF15905.5 EGO60875.1 - 0.14 11.6 29.9 0.23 10.9 29.9 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal BLOC1_2 PF10046.9 EGO60875.1 - 0.17 12.2 24.0 1.2 9.5 1.0 3.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-H PF05837.12 EGO60875.1 - 0.2 12.1 26.1 1.8 9.0 11.0 3.0 1 1 2 3 3 3 0 Centromere protein H (CENP-H) UPF0242 PF06785.11 EGO60875.1 - 0.22 11.6 34.0 0.73 9.9 15.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF812 PF05667.11 EGO60875.1 - 0.27 10.1 30.6 0.41 9.5 30.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FapA PF03961.13 EGO60875.1 - 0.33 9.5 26.8 0.46 9.0 7.8 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A TANGO2 PF05742.12 EGO60875.1 - 0.34 10.9 7.3 0.5 10.4 7.3 1.5 1 1 0 1 1 1 0 Transport and Golgi organisation 2 KASH_CCD PF14662.6 EGO60875.1 - 0.34 10.7 32.8 2 8.2 28.3 2.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Lebercilin PF15619.6 EGO60875.1 - 0.37 10.4 33.1 2 8.0 18.7 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease MAD PF05557.13 EGO60875.1 - 0.43 8.9 29.0 1.5 7.1 29.0 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF2203 PF09969.9 EGO60875.1 - 0.46 11.2 19.3 1.2 9.8 4.8 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cep57_MT_bd PF06657.13 EGO60875.1 - 0.47 10.9 23.3 0.31 11.5 1.2 3.7 2 2 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 LPP PF04728.13 EGO60875.1 - 0.51 10.8 13.5 4.2 7.8 2.1 3.9 2 1 1 3 3 3 0 Lipoprotein leucine-zipper DUF3584 PF12128.8 EGO60875.1 - 0.57 7.6 27.6 0.62 7.5 27.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF745 PF05335.13 EGO60875.1 - 0.64 9.7 24.9 0.033 13.9 5.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Spc29 PF17082.5 EGO60875.1 - 0.68 9.7 18.0 3.1 7.6 1.4 3.0 1 1 1 2 2 2 0 Spindle Pole Component 29 CLZ PF16526.5 EGO60875.1 - 0.7 10.3 25.7 11 6.4 5.7 3.8 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fmp27_WPPW PF10359.9 EGO60875.1 - 0.74 8.6 25.5 0.15 10.9 8.6 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain ZapB PF06005.12 EGO60875.1 - 0.76 10.3 40.0 5.5 7.5 8.1 4.1 1 1 2 3 3 2 0 Cell division protein ZapB Seryl_tRNA_N PF02403.22 EGO60875.1 - 0.81 10.0 28.6 3 8.1 0.7 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Vps5 PF09325.10 EGO60875.1 - 0.85 9.1 22.9 0.12 11.9 7.3 2.6 1 1 0 2 2 2 0 Vps5 C terminal like KELK PF15796.5 EGO60875.1 - 1.1 9.8 33.5 0.4 11.2 3.2 4.0 2 2 2 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Sec34 PF04136.15 EGO60875.1 - 1.1 9.1 19.6 0.35 10.7 4.2 2.4 1 1 0 2 2 2 0 Sec34-like family CASP_C PF08172.12 EGO60875.1 - 1.4 8.2 22.6 0.14 11.5 2.1 2.1 1 1 1 2 2 2 0 CASP C terminal TPR_MLP1_2 PF07926.12 EGO60875.1 - 1.5 8.9 38.4 15 5.7 17.4 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4686 PF15742.5 EGO60875.1 - 1.7 7.7 33.3 0.62 9.1 25.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) Swi5 PF07061.11 EGO60875.1 - 1.7 8.8 27.1 0.98 9.6 1.0 4.1 1 1 3 4 4 4 0 Swi5 YabA PF06156.13 EGO60875.1 - 1.7 9.3 22.5 91 3.8 7.2 2.8 1 1 1 2 2 2 0 Initiation control protein YabA Ax_dynein_light PF10211.9 EGO60875.1 - 1.9 8.4 33.5 2.6 8.0 4.5 3.7 1 1 2 3 3 3 0 Axonemal dynein light chain DUF4201 PF13870.6 EGO60875.1 - 2.3 7.9 25.6 4.2 7.1 17.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) MIS13 PF08202.11 EGO60875.1 - 2.8 7.1 21.9 0.74 9.0 6.3 2.3 1 1 1 2 2 2 0 Mis12-Mtw1 protein family Cep57_CLD_2 PF14197.6 EGO60875.1 - 2.9 8.0 28.3 1.8 8.7 1.0 4.1 2 2 1 3 3 3 0 Centrosome localisation domain of PPC89 Nup88 PF10168.9 EGO60875.1 - 2.9 5.6 22.4 5 4.8 22.3 1.4 1 1 0 1 1 1 0 Nuclear pore component Leu_zip PF15294.6 EGO60875.1 - 3.2 7.2 25.3 13 5.2 24.9 1.8 1 1 0 1 1 1 0 Leucine zipper FUSC PF04632.12 EGO60875.1 - 3.2 6.2 6.3 3.4 6.1 6.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4482 PF14818.6 EGO60875.1 - 3.3 8.6 24.8 0.15 12.9 2.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) DUF16 PF01519.16 EGO60875.1 - 3.6 8.1 24.7 2.5 8.6 7.7 3.1 1 1 2 3 3 3 0 Protein of unknown function DUF16 Rootletin PF15035.6 EGO60875.1 - 4 7.4 30.6 0.96 9.4 10.7 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4407 PF14362.6 EGO60875.1 - 4.2 6.6 22.5 9.9 5.4 22.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Lectin_N PF03954.14 EGO60875.1 - 4.9 6.9 18.6 5.9 6.6 4.6 3.0 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Methyltransf_9 PF08003.11 EGO60875.1 - 5 6.0 7.6 0.73 8.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) T2SSM PF04612.12 EGO60875.1 - 5.2 7.1 15.4 0.62 10.1 0.7 2.9 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein M CHDCT2 PF08074.11 EGO60875.1 - 5.4 7.2 12.5 0.63 10.2 4.5 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Peptidase_S64 PF08192.11 EGO60875.1 - 6.5 5.1 14.3 6.9 5.0 14.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 SHE3 PF17078.5 EGO60875.1 - 6.7 6.4 25.3 2.8 7.6 8.1 2.5 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Mod_r PF07200.13 EGO60875.1 - 6.9 6.8 29.5 8.2 6.5 20.0 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF948 PF06103.11 EGO60875.1 - 7.2 6.9 12.6 10 6.4 1.8 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Phage_HK97_TLTM PF06120.11 EGO60875.1 - 7.3 5.7 21.7 3.8 6.6 15.3 2.1 1 1 1 2 2 2 0 Tail length tape measure protein TRAF_BIRC3_bd PF16673.5 EGO60875.1 - 8 6.3 21.3 4.6 7.1 0.9 3.9 1 1 4 5 5 5 0 TNF receptor-associated factor BIRC3 binding domain PI3K_P85_iSH2 PF16454.5 EGO60875.1 - 8.5 5.9 27.3 69 3.0 26.7 2.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TMCO5 PF14992.6 EGO60875.1 - 8.6 5.9 28.4 2.1e+02 1.3 28.6 2.1 1 1 0 1 1 1 0 TMCO5 family AAA_13 PF13166.6 EGO60875.1 - 9.5 4.7 25.8 1 7.9 9.9 1.9 1 1 0 1 1 1 0 AAA domain Paralemmin PF03285.15 EGO60875.1 - 9.8 5.6 23.4 7 6.1 3.8 2.1 1 1 1 2 2 2 0 Paralemmin DUF4795 PF16043.5 EGO60875.1 - 9.9 5.7 26.3 52 3.4 26.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) TMPIT PF07851.13 EGO60875.1 - 10 5.3 23.7 4.3 6.5 7.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein Nop25 PF09805.9 EGO60876.1 - 8.3e-40 136.4 15.9 8.3e-40 136.4 15.9 2.3 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) zf-CpG_bind_C PF12269.8 EGO60876.1 - 0.023 14.5 3.7 0.023 14.5 3.7 2.1 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain ATP-synt_S1 PF05827.12 EGO60877.1 - 0.00021 21.1 0.1 0.0012 18.7 0.0 1.9 2 0 0 2 2 2 1 Vacuolar ATP synthase subunit S1 (ATP6S1) T3SS_needle_E PF08988.10 EGO60877.1 - 0.077 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle Trm112p PF03966.16 EGO60878.1 - 3.5e-17 62.7 0.1 4.2e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.6 EGO60878.1 - 0.0084 16.6 0.4 0.014 15.9 0.4 1.3 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain zf-BED PF02892.15 EGO60878.1 - 0.048 13.7 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 BED zinc finger Pro_isomerase PF00160.21 EGO60879.1 - 1.1e-48 165.5 0.2 1.4e-48 165.1 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Syntaxin-6_N PF09177.11 EGO60880.1 - 4.2e-24 85.0 2.0 6.4e-24 84.4 0.5 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EGO60880.1 - 0.00027 20.8 0.7 0.00056 19.8 0.2 1.9 2 0 0 2 2 2 1 SNARE domain Pox_EPC_I2-L1 PF12575.8 EGO60880.1 - 0.04 14.1 3.7 32 4.8 0.0 3.4 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 CENP-Q PF13094.6 EGO60880.1 - 0.36 11.0 6.0 11 6.2 0.2 3.0 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1515 PF07439.11 EGO60880.1 - 0.81 9.7 3.5 34 4.5 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) ATG16 PF08614.11 EGO60880.1 - 1.2 9.3 10.7 1.4 9.1 1.1 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DegS PF05384.11 EGO60880.1 - 1.9 8.0 6.6 1.7 8.1 2.6 2.6 2 2 1 3 3 3 0 Sensor protein DegS Vps5 PF09325.10 EGO60880.1 - 9.3 5.7 7.7 0.95 9.0 0.8 2.5 3 0 0 3 3 3 0 Vps5 C terminal like GLE1 PF07817.13 EGO60881.1 - 8.1e-59 198.9 0.0 1.1e-58 198.5 0.0 1.1 1 0 0 1 1 1 1 GLE1-like protein RNB PF00773.19 EGO60882.1 - 1.1e-74 251.8 0.0 1.7e-74 251.1 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 EGO60882.1 - 3.6e-27 94.2 0.0 9.6e-27 92.8 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 EGO60882.1 - 2.2e-25 88.8 0.0 6.4e-25 87.3 0.0 1.8 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 EGO60882.1 - 5.3e-07 29.7 0.0 0.004 17.3 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 EGO60882.1 - 0.0029 17.3 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain Ferritin_2 PF13668.6 EGO60883.1 - 1.1e-39 135.8 3.7 1.7e-39 135.1 3.7 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF4439 PF14530.6 EGO60883.1 - 0.0052 17.5 1.5 0.01 16.5 1.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4439) ELFV_dehydrog PF00208.21 EGO60884.1 - 3.3e-82 275.9 5.2 4.1e-82 275.5 5.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EGO60884.1 - 1.7e-50 170.3 0.0 2.7e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 EGO60884.1 - 0.018 15.5 0.1 0.049 14.1 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Semialdhyde_dh PF01118.24 EGO60884.1 - 0.14 12.6 0.1 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain GMC_oxred_C PF05199.13 EGO60885.1 - 3e-11 44.0 0.8 6.3e-09 36.5 0.3 3.0 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EGO60885.1 - 4e-08 33.0 0.3 3.5e-07 29.9 0.3 2.4 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGO60885.1 - 0.00014 21.1 0.3 0.00029 20.0 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGO60885.1 - 0.0023 17.4 0.5 0.0041 16.5 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Abhydrolase_1 PF00561.20 EGO60885.1 - 0.0066 16.1 0.0 0.026 14.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Pyr_redox_2 PF07992.14 EGO60885.1 - 0.0081 15.4 0.1 0.015 14.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO60885.1 - 0.014 15.6 0.1 0.043 14.0 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Hydrolase_4 PF12146.8 EGO60885.1 - 0.016 14.5 0.0 0.79 8.9 0.0 2.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Lycopene_cycl PF05834.12 EGO60885.1 - 0.026 13.6 0.1 0.07 12.2 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 EGO60885.1 - 0.028 14.0 0.2 0.52 9.8 0.2 2.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase GhoS PF11080.8 EGO60885.1 - 0.032 14.2 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease GhoS Pyr_redox PF00070.27 EGO60885.1 - 0.085 13.4 0.0 0.24 12.0 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF900 PF05990.12 EGO60885.1 - 0.086 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) FAD_binding_3 PF01494.19 EGO60885.1 - 0.089 12.0 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EGO60885.1 - 0.097 11.7 0.2 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 EGO60885.1 - 0.17 10.6 0.1 0.24 10.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein DNA_pol_B PF00136.21 EGO60886.1 - 9e-150 499.4 1.4 1.3e-149 498.8 1.4 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGO60886.1 - 5e-82 275.7 0.1 5e-82 275.7 0.1 1.9 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EGO60886.1 - 3.2e-15 56.4 4.0 7.3e-15 55.2 4.0 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EGO60886.1 - 0.00027 19.9 0.2 0.0088 14.9 0.0 2.4 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 EGO60886.1 - 0.00065 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EGO60886.1 - 0.018 15.0 0.3 0.13 12.3 0.3 2.5 1 1 0 1 1 1 0 RNase_H superfamily DUF2508 PF10704.9 EGO60886.1 - 1 9.6 3.4 6.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) C1_1 PF00130.22 EGO60886.1 - 2.9 7.9 9.2 1.2 9.1 0.7 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TFIIA PF03153.13 EGO60887.1 - 0.002 18.2 6.2 0.0022 18.1 6.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit LprI PF07007.12 EGO60887.1 - 0.046 14.4 0.1 0.12 13.0 0.1 1.7 1 1 0 1 1 1 0 Lysozyme inhibitor LprI ATF7IP_BD PF16788.5 EGO60887.1 - 1.7 8.7 4.9 3.2 7.8 4.9 1.4 1 0 0 1 1 1 0 ATF-interacting protein binding domain DUF410 PF04190.13 EGO60888.1 - 1.3e-88 297.1 0.0 1.6e-88 296.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) CUE PF02845.16 EGO60890.1 - 0.00081 19.0 0.0 0.0022 17.6 0.0 1.8 1 0 0 1 1 1 1 CUE domain UIM PF02809.20 EGO60890.1 - 0.022 14.6 2.8 0.076 13.0 2.8 2.0 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF2397 PF09660.10 EGO60890.1 - 0.048 12.6 0.0 0.091 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) UBM PF14377.6 EGO60890.1 - 0.42 10.1 0.0 0.42 10.1 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin binding region UQ_con PF00179.26 EGO60891.1 - 1.1e-34 119.1 0.0 1.4e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO60891.1 - 0.042 13.5 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B HGTP_anticodon2 PF12745.7 EGO60892.1 - 1.4e-88 296.9 4.3 7.1e-88 294.5 0.0 2.6 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 EGO60892.1 - 8.3e-78 261.4 0.1 7.3e-38 130.4 0.0 4.2 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGO60892.1 - 8.2e-47 159.7 0.0 4.4e-21 75.3 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 EGO60892.1 - 9.6e-13 48.1 0.6 2.4e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.22 EGO60892.1 - 2.5e-11 43.9 3.2 3.2e-11 43.5 0.2 2.6 2 0 0 2 2 2 1 RWD domain YrbL-PhoP_reg PF10707.9 EGO60892.1 - 9.6e-06 25.2 0.0 0.0047 16.5 0.0 2.8 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL APH PF01636.23 EGO60892.1 - 0.00021 21.3 2.1 0.75 9.7 0.1 3.1 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGO60892.1 - 0.00049 19.5 0.0 0.0026 17.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGO60892.1 - 0.0057 15.5 9.5 0.097 11.4 0.1 3.2 3 0 0 3 3 3 2 Fungal protein kinase Kdo PF06293.14 EGO60892.1 - 0.0069 15.8 0.1 4.5 6.6 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGO60892.1 - 0.023 14.3 0.1 2.3 7.8 0.0 3.3 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 PVL_ORF50 PF07768.11 EGO60892.1 - 0.29 11.4 5.1 1.6 9.0 5.1 2.4 1 0 0 1 1 1 0 PVL ORF-50-like family CDC45 PF02724.14 EGO60892.1 - 0.9 7.8 11.7 1.2 7.4 1.4 2.1 2 0 0 2 2 2 0 CDC45-like protein UreF PF01730.16 EGO60893.1 - 1.9e-23 83.5 0.2 1.9e-23 83.5 0.2 2.0 2 0 0 2 2 2 1 UreF Sugarporin_N PF11471.8 EGO60893.1 - 0.041 13.8 7.3 0.19 11.7 7.3 2.2 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Pox_A_type_inc PF04508.12 EGO60893.1 - 0.16 11.9 1.4 0.4 10.6 1.4 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF429 PF04250.13 EGO60893.1 - 0.29 10.9 0.1 0.29 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF429) Csm1_N PF18504.1 EGO60893.1 - 0.94 9.9 5.5 1.4 9.3 5.5 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF4140 PF13600.6 EGO60893.1 - 1.6 9.2 6.2 3.4 8.2 6.2 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Torus PF16131.5 EGO60894.1 - 6.7e-45 152.3 0.7 1.6e-44 151.0 0.0 2.0 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 EGO60894.1 - 6.8e-09 35.4 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EGO60894.1 - 0.00013 21.9 0.6 0.00013 21.9 0.6 1.9 2 0 0 2 2 2 1 Zinc finger domain Nup35_RRM_2 PF14605.6 EGO60894.1 - 0.00068 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 EGO60894.1 - 0.027 14.4 0.7 0.052 13.5 0.7 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1_Xtn PF16897.5 EGO60895.1 - 1e-34 118.7 1.8 3.2e-34 117.1 0.7 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EGO60895.1 - 4e-21 75.2 0.2 9.6e-21 74.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 EGO60895.1 - 8e-21 73.9 0.0 1.6e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EGO60895.1 - 5.8e-13 48.7 0.0 9.2e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGO60895.1 - 0.00067 19.8 3.4 0.055 13.5 0.0 2.6 2 1 1 3 3 3 2 Dynamin family MeaB PF03308.16 EGO60895.1 - 0.089 11.8 0.1 0.17 10.8 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 EGO60895.1 - 0.1 11.7 0.0 0.23 10.5 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain Spo12 PF05032.12 EGO60896.1 - 1.2e-15 57.1 1.6 2.8e-15 55.9 1.6 1.7 1 0 0 1 1 1 1 Spo12 family Nucleoporin_FG PF13634.6 EGO60896.1 - 0.21 12.5 9.1 0.79 10.6 5.2 2.1 2 0 0 2 2 2 0 Nucleoporin FG repeat region Acyl-CoA_dh_1 PF00441.24 EGO60898.1 - 3.7e-29 101.9 0.4 6.4e-29 101.1 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGO60898.1 - 7.4e-20 71.0 0.0 1.4e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGO60898.1 - 3.1e-14 53.6 0.0 6.5e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGO60898.1 - 8.8e-14 51.9 0.6 2e-13 50.8 0.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UCH_1 PF13423.6 EGO60900.1 - 2.1e-36 126.1 0.0 2.9e-35 122.4 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Porin_3 PF01459.22 EGO60901.1 - 2.9e-80 269.6 0.5 3.4e-80 269.4 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.18 EGO60902.1 - 1.3e-60 204.5 0.0 1.9e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGO60902.1 - 1.6e-22 80.2 0.4 2.1e-21 76.5 0.4 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGO60902.1 - 0.0014 18.8 0.0 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain ZnuA PF01297.17 EGO60902.1 - 0.0043 16.5 0.0 0.011 15.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic RmlD_sub_bind PF04321.17 EGO60903.1 - 2e-50 171.5 0.0 2.6e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EGO60903.1 - 1.2e-21 77.3 0.0 1.6e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGO60903.1 - 3.7e-10 39.7 0.0 5.3e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGO60903.1 - 1.4e-08 34.3 0.1 3.2e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 EGO60903.1 - 1.5e-08 34.0 0.0 2.2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGO60903.1 - 3.2e-08 33.0 0.0 6.3e-05 22.3 0.0 2.5 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGO60903.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 EGO60903.1 - 0.029 13.9 0.0 0.42 10.1 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family PH PF00169.29 EGO60904.1 - 2.4e-05 24.8 0.1 7.6e-05 23.2 0.1 1.9 1 0 0 1 1 1 1 PH domain polyprenyl_synt PF00348.17 EGO60905.1 - 2.9e-93 311.6 0.0 3.6e-93 311.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase YkyB PF14177.6 EGO60905.1 - 0.034 14.5 0.0 0.076 13.3 0.0 1.5 1 0 0 1 1 1 0 YkyB-like protein Homeodomain PF00046.29 EGO60905.1 - 0.13 12.2 0.1 0.51 10.2 0.1 2.0 2 0 0 2 2 2 0 Homeodomain ANAPC8 PF04049.13 EGO60906.1 - 9.9e-38 129.3 0.9 2.2e-37 128.2 0.0 2.0 3 0 0 3 3 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 EGO60906.1 - 9.4e-20 69.5 10.9 0.00041 20.0 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO60906.1 - 1.6e-18 65.3 12.5 6.8e-05 22.8 0.0 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGO60906.1 - 1.4e-13 49.8 21.3 0.23 11.6 0.0 9.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGO60906.1 - 8.5e-11 41.7 17.2 0.0056 17.4 0.1 8.2 7 2 2 9 9 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGO60906.1 - 8.8e-09 35.9 7.4 3.7e-06 27.5 1.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO60906.1 - 1.3e-06 28.6 14.3 0.66 10.3 0.1 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGO60906.1 - 2.4e-06 27.1 0.1 2.4e-06 27.1 0.1 3.5 3 1 1 4 4 3 1 TPR repeat TPR_19 PF14559.6 EGO60906.1 - 1.5e-05 25.4 1.9 6.6 7.3 0.0 5.9 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO60906.1 - 4e-05 23.4 6.4 0.083 13.0 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGO60906.1 - 0.00032 20.8 14.8 1.6 8.9 0.3 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGO60906.1 - 0.00059 20.0 4.1 9.6 6.8 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO60906.1 - 0.0013 18.9 9.3 0.067 13.4 0.4 5.2 5 1 1 6 6 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGO60906.1 - 0.0021 17.9 4.6 0.5 10.3 0.1 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 EGO60906.1 - 0.0023 18.0 2.8 0.05 13.7 0.2 3.1 2 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 EGO60906.1 - 0.078 13.7 16.0 1.3 9.8 0.2 7.2 7 0 0 7 7 6 0 Tetratricopeptide repeat Say1_Mug180 PF10340.9 EGO60906.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase TPR_15 PF13429.6 EGO60906.1 - 0.16 11.2 6.8 0.27 10.4 1.7 3.6 3 1 2 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.12 EGO60906.1 - 4.6 8.1 9.4 50 4.8 1.1 4.7 5 0 0 5 5 4 0 Sel1 repeat Vps54 PF07928.12 EGO60908.1 - 5.3e-38 130.5 13.3 8.2e-36 123.4 6.7 4.1 3 1 0 3 3 3 1 Vps54-like protein Vps54_N PF10475.9 EGO60908.1 - 1.3e-06 28.0 2.4 2.7e-06 26.9 0.4 2.1 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 EGO60908.1 - 0.021 14.9 3.8 0.48 10.5 1.5 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FliJ PF02050.16 EGO60908.1 - 0.063 13.5 0.3 0.19 12.0 0.3 1.8 1 0 0 1 1 1 0 Flagellar FliJ protein CENP-F_leu_zip PF10473.9 EGO60908.1 - 0.068 13.2 0.3 0.22 11.5 0.3 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MCM PF00493.23 EGO60909.1 - 7.6e-105 349.0 0.1 1.6e-104 347.9 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EGO60909.1 - 7.5e-37 126.0 0.2 1.3e-36 125.2 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGO60909.1 - 6e-29 100.3 2.2 1.4e-28 99.1 2.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGO60909.1 - 1.6e-14 54.3 0.3 4e-14 53.1 0.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGO60909.1 - 3.5e-07 29.8 0.0 0.00021 20.7 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGO60909.1 - 8.1e-05 22.6 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGO60909.1 - 0.00061 19.6 0.0 0.0025 17.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGO60909.1 - 0.048 13.4 0.1 0.62 9.8 0.1 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 EGO60909.1 - 0.11 13.1 1.3 0.32 11.7 0.6 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal AAA_30 PF13604.6 EGO60909.1 - 0.11 12.2 0.3 0.25 11.0 0.3 1.5 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.28 EGO60910.1 - 2.1e-17 62.8 0.0 3.2e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme KOW PF00467.29 EGO60910.1 - 0.22 11.5 0.1 0.41 10.7 0.1 1.4 1 0 0 1 1 1 0 KOW motif 2Fe-2S_thioredx PF01257.19 EGO60911.1 - 3.2e-59 198.9 0.1 4.1e-59 198.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Kelch_4 PF13418.6 EGO60912.1 - 6.7e-21 74.0 9.6 3.7e-07 30.0 0.0 7.0 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EGO60912.1 - 7.2e-19 67.4 1.2 1.5e-05 24.9 0.0 7.1 7 0 0 7 7 7 5 Kelch motif Kelch_3 PF13415.6 EGO60912.1 - 1.4e-15 57.1 13.9 3e-05 24.2 0.0 6.9 6 2 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EGO60912.1 - 3.1e-15 55.8 6.2 0.0002 21.5 0.1 5.9 6 1 1 7 7 7 3 Kelch motif Kelch_1 PF01344.25 EGO60912.1 - 4.3e-15 55.0 5.6 1.1e-06 28.1 0.0 5.8 7 0 0 7 7 7 3 Kelch motif Kelch_2 PF07646.15 EGO60912.1 - 5.1e-10 38.9 6.0 1.8e-05 24.5 0.6 5.8 5 1 0 5 5 5 1 Kelch motif Ceramidase_alk PF04734.13 EGO60913.1 - 6.3e-221 734.4 0.0 7.4e-221 734.2 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EGO60913.1 - 5.9e-56 188.9 0.1 1e-55 188.2 0.1 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal PsbX PF06596.11 EGO60913.1 - 1.5 8.9 5.8 3 7.9 5.8 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) BCAS2 PF05700.11 EGO60914.1 - 8e-55 185.7 0.0 8.9e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.8 EGO60914.1 - 0.042 14.1 0.1 0.067 13.4 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding cNMP_binding PF00027.29 EGO60915.1 - 1.2e-39 134.3 0.0 1.5e-18 66.6 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF4048 PF13257.6 EGO60915.1 - 0.019 14.8 0.4 0.032 14.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) CDC50 PF03381.15 EGO60916.1 - 7.2e-81 271.8 0.0 8.7e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family FACT-Spt16_Nlob PF14826.6 EGO60917.1 - 7.8e-58 194.8 0.4 2.8e-57 193.0 0.4 2.1 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 EGO60917.1 - 1.8e-54 184.0 0.1 1.8e-54 184.0 0.1 3.0 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 EGO60917.1 - 3.9e-26 92.1 0.0 8.2e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EGO60917.1 - 4.5e-16 59.0 0.9 9.9e-16 57.9 0.1 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like GAF_2 PF13185.6 EGO60918.1 - 2.2e-11 44.2 0.0 4.1e-11 43.3 0.0 1.4 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 EGO60918.1 - 1.1e-05 26.1 0.0 1.3e-05 25.8 0.0 1.2 1 1 0 1 1 1 1 GAF domain Glyco_hydro_72 PF03198.14 EGO60919.1 - 2e-122 408.4 2.9 2.3e-122 408.2 2.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EGO60919.1 - 8.6e-07 28.7 0.6 1.3e-05 24.8 0.6 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2713 PF10897.8 EGO60919.1 - 0.014 15.1 0.3 0.029 14.0 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2713) SH3_9 PF14604.6 EGO60920.1 - 6.6e-21 73.9 1.5 5.1e-14 51.9 0.1 2.7 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 EGO60920.1 - 4.1e-18 65.4 0.0 4.1e-18 65.4 0.0 3.3 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 EGO60920.1 - 2.6e-15 56.0 5.6 4.2e-15 55.4 5.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 EGO60920.1 - 2.2e-11 43.2 0.1 5.6e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_2 PF03107.16 EGO60920.1 - 0.0087 16.4 4.8 0.016 15.5 4.8 1.4 1 0 0 1 1 1 1 C1 domain SH3_10 PF17902.1 EGO60920.1 - 0.017 15.2 0.0 0.084 13.0 0.0 2.2 2 0 0 2 2 2 0 SH3 domain SH3_2 PF07653.17 EGO60920.1 - 0.044 13.5 0.2 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Variant SH3 domain SH3_3 PF08239.11 EGO60920.1 - 0.081 13.2 1.3 4.2 7.7 0.1 2.6 2 0 0 2 2 2 0 Bacterial SH3 domain zf-RING_9 PF13901.6 EGO60920.1 - 0.67 9.9 13.0 0.066 13.2 2.9 2.6 2 1 0 2 2 2 0 Putative zinc-RING and/or ribbon DEAD PF00270.29 EGO60921.1 - 5.8e-36 123.9 0.3 1e-34 119.9 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO60921.1 - 2.9e-24 85.5 0.0 6.4e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO60921.1 - 2.4e-06 27.7 0.0 4.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EGO60921.1 - 0.00044 20.0 0.0 0.00086 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 EGO60921.1 - 0.0077 15.6 0.1 0.015 14.6 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 EGO60921.1 - 0.029 14.7 0.0 0.47 10.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGO60921.1 - 0.075 13.3 0.7 0.89 9.8 0.5 2.6 2 1 0 2 2 2 0 AAA domain GCS PF03074.16 EGO60925.1 - 3.1e-174 579.6 0.0 3.9e-174 579.2 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF4293 PF14126.6 EGO60926.1 - 3.6 7.8 8.8 3.4 7.9 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) GATA PF00320.27 EGO60929.1 - 5.1e-16 58.0 3.5 8.3e-16 57.3 3.5 1.4 1 0 0 1 1 1 1 GATA zinc finger DUF1741 PF08427.10 EGO60929.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) DFP PF04127.15 EGO60929.1 - 0.26 11.1 0.1 0.45 10.3 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Prion_bPrPp PF11587.8 EGO60930.1 - 0.048 13.5 0.0 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal DUF4380 PF14315.6 EGO60931.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) Peptidase_C2 PF00648.21 EGO60932.1 - 4.4e-59 199.9 0.2 2.5e-58 197.5 0.2 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease Prion_octapep PF03991.12 EGO60932.1 - 1.7 9.7 5.4 7.9 7.6 5.4 2.2 1 0 0 1 1 1 0 Copper binding octapeptide repeat ArfGap PF01412.18 EGO60933.1 - 2.5e-39 134.0 0.2 2.5e-39 134.0 0.2 2.8 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Cupin_5 PF06172.11 EGO60934.1 - 8.5e-41 139.4 0.0 1.1e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Methyltransf_23 PF13489.6 EGO60935.1 - 1.1e-21 77.3 0.0 1.5e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO60935.1 - 3.8e-11 43.5 0.0 8.3e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO60935.1 - 1.6e-09 38.4 0.0 1.3e-08 35.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO60935.1 - 9.6e-09 35.2 0.0 1.2e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO60935.1 - 9.9e-06 26.1 0.0 1.9e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO60935.1 - 0.0019 17.6 0.0 0.014 14.8 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EGO60935.1 - 0.0022 17.5 0.0 0.0056 16.2 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EGO60935.1 - 0.0046 16.5 0.0 0.056 13.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 EGO60935.1 - 0.0072 16.4 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EGO60935.1 - 0.018 14.8 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Lysine methyltransferase Methyltransf_2 PF00891.18 EGO60935.1 - 0.097 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Pyridoxal_deC PF00282.19 EGO60936.1 - 1.4e-20 73.4 0.0 2.5e-20 72.6 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EGO60936.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EGO60936.1 - 0.023 13.9 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II TRAP_alpha PF03896.16 EGO60937.1 - 1.2e-10 41.1 0.0 1.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit HA2 PF04408.23 EGO60940.1 - 1.4e-18 67.2 0.5 2e-17 63.4 0.0 2.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGO60940.1 - 2.8e-17 62.9 0.0 6.6e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGO60940.1 - 9.6e-16 58.1 0.0 2.4e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO60940.1 - 7.1e-11 42.2 0.1 1.3e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 EGO60940.1 - 3.1e-05 24.2 0.3 6.9e-05 23.1 0.3 1.6 1 0 0 1 1 1 1 RWD domain AAA_22 PF13401.6 EGO60940.1 - 0.0028 17.9 0.3 0.011 16.0 0.3 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EGO60940.1 - 0.0047 16.9 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EGO60940.1 - 0.0065 15.6 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 EGO60940.1 - 0.012 15.0 0.1 0.024 14.0 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 EGO60940.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EGO60940.1 - 0.026 15.1 0.7 0.3 11.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain DND1_DSRM PF14709.7 EGO60940.1 - 0.026 14.8 0.0 0.12 12.7 0.0 2.3 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 MukB PF04310.12 EGO60940.1 - 0.028 14.2 0.0 34 4.2 0.0 3.2 3 0 0 3 3 3 0 MukB N-terminal PhoH PF02562.16 EGO60940.1 - 0.03 13.8 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EGO60940.1 - 0.059 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGO60940.1 - 0.12 12.1 0.1 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein PLDc_2 PF13091.6 EGO60942.1 - 3.1e-15 56.2 0.0 1.1e-07 31.8 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EGO60942.1 - 2.6e-08 33.7 1.8 0.0031 17.6 0.2 3.1 2 1 0 2 2 2 2 Phospholipase D Active site motif PNTB PF02233.16 EGO60943.1 - 2.3e-174 580.7 24.9 2.3e-174 580.7 24.9 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EGO60943.1 - 9.3e-74 247.3 0.6 9.3e-74 247.3 0.6 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EGO60943.1 - 5.9e-50 169.1 0.1 1.6e-49 167.7 0.1 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EGO60943.1 - 1.4e-30 105.5 2.3 1.4e-30 105.5 2.3 5.6 5 1 1 6 6 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch ADH_zinc_N PF00107.26 EGO60943.1 - 0.014 15.4 0.3 0.089 12.8 0.3 2.4 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 EGO60943.1 - 0.014 14.6 0.1 0.04 13.2 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EGO60943.1 - 0.018 14.4 0.2 0.69 9.3 0.1 2.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EGO60943.1 - 0.026 14.7 2.1 0.65 10.1 0.2 3.2 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 EGO60943.1 - 0.097 11.7 1.1 0.17 11.0 1.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fumerase PF05681.14 EGO60943.1 - 0.11 11.9 0.2 0.19 11.1 0.2 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) TPP_enzyme_M PF00205.22 EGO60943.1 - 0.17 11.6 0.9 1.4 8.6 0.3 2.9 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain NmrA PF05368.13 EGO60944.1 - 2.7e-08 33.7 0.0 4.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGO60944.1 - 5e-08 33.0 0.0 9.8e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EGO60944.1 - 1.9e-06 28.1 0.0 3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 EGO60944.1 - 0.00037 21.3 0.0 0.00071 20.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Epimerase PF01370.21 EGO60944.1 - 0.1 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F-box-like PF12937.7 EGO60946.1 - 4.6e-06 26.4 0.2 1.7e-05 24.6 0.2 2.1 1 0 0 1 1 1 1 F-box-like MCC-bdg_PDZ PF10506.9 EGO60946.1 - 0.033 14.2 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome BUD22 PF09073.10 EGO60946.1 - 2.9 7.1 45.1 4.5 6.5 45.1 1.2 1 0 0 1 1 1 0 BUD22 p450 PF00067.22 EGO60947.1 - 8.2e-53 179.8 0.0 6.5e-52 176.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Cation_efflux PF01545.21 EGO60947.1 - 0.19 11.4 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Cation efflux family Sugar_tr PF00083.24 EGO60949.1 - 5.8e-115 384.7 17.1 7.2e-115 384.4 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO60949.1 - 9.9e-22 77.3 26.1 7.3e-15 54.7 4.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.12 EGO60950.1 - 8.2e-06 25.7 0.1 1e-05 25.4 0.1 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GFA PF04828.14 EGO60951.1 - 1e-18 67.4 1.4 1.5e-18 66.9 1.4 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Tnp_zf-ribbon_2 PF13842.6 EGO60951.1 - 0.053 14.3 0.3 0.053 14.3 0.3 2.6 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon DUF2163 PF09931.9 EGO60951.1 - 0.13 12.5 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) Peptidase_C97 PF05903.14 EGO60952.1 - 0.0024 17.7 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EGO60952.1 - 0.058 13.7 0.1 1.3 9.3 0.0 2.3 1 1 1 2 2 2 0 Lecithin retinol acyltransferase FAD_binding_4 PF01565.23 EGO60953.1 - 6.9e-25 87.4 3.9 1.6e-24 86.2 3.1 2.0 2 0 0 2 2 2 1 FAD binding domain Fungal_trans PF04082.18 EGO60954.1 - 2.4e-56 190.7 0.1 3.8e-56 190.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EGO60954.1 - 1.2e-05 25.5 15.5 0.00045 20.5 1.1 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO60954.1 - 0.00012 22.6 6.5 0.15 12.9 0.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger Ank_2 PF12796.7 EGO60955.1 - 1.6e-21 76.7 5.0 9e-11 42.2 0.4 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO60955.1 - 7.6e-16 58.3 3.2 3.6e-08 33.8 0.3 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO60955.1 - 1.7e-14 53.7 0.4 2.6e-08 34.0 0.3 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGO60955.1 - 2e-11 43.8 0.8 7.3e-05 23.0 0.5 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGO60955.1 - 6.1e-09 35.4 0.1 0.004 17.5 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat RHH_1 PF01402.21 EGO60955.1 - 0.21 11.6 0.7 0.47 10.5 0.1 1.9 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family TP6A_N PF04406.14 EGO60956.1 - 2.8e-21 75.2 1.1 2.7e-20 72.1 0.1 2.7 3 0 0 3 3 3 1 Type IIB DNA topoisomerase DUF1707 PF08044.11 EGO60956.1 - 0.47 10.5 2.4 0.34 11.0 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) SQHop_cyclase_C PF13243.6 EGO60957.1 - 2.3e-46 158.4 0.7 3.2e-44 151.3 0.5 2.4 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EGO60957.1 - 2.2e-39 135.3 4.7 6.4e-35 120.7 1.4 3.1 3 1 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EGO60957.1 - 1.6e-28 98.1 3.7 7.8e-09 35.1 0.1 4.7 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 EGO60957.1 - 3.1e-05 23.1 0.2 0.012 14.7 0.0 2.9 2 1 1 3 3 3 2 A-macroglobulin TED domain Pec_lyase PF09492.10 EGO60957.1 - 5.3e-05 22.7 0.1 0.0079 15.6 0.0 3.6 2 1 1 4 4 4 1 Pectic acid lyase SGS PF05002.15 EGO60958.1 - 2e-27 95.1 0.5 7.3e-27 93.3 0.5 2.0 1 0 0 1 1 1 1 SGS domain CS PF04969.16 EGO60958.1 - 1.7e-16 61.0 0.1 4.3e-16 59.7 0.0 1.7 2 0 0 2 2 2 1 CS domain TPR_2 PF07719.17 EGO60958.1 - 0.00013 21.8 7.0 0.11 12.7 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGO60958.1 - 0.00058 19.6 4.4 0.062 13.2 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGO60958.1 - 0.0026 18.2 4.4 0.29 11.7 0.6 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGO60958.1 - 0.0083 16.8 8.1 0.12 13.0 2.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGO60958.1 - 0.025 14.9 8.4 3.4 8.0 5.7 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGO60958.1 - 0.13 11.9 0.3 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.6 EGO60958.1 - 0.2 11.9 3.0 15 6.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_21 PF13506.6 EGO60959.1 - 3.8e-12 46.0 0.1 4.7e-05 22.9 0.0 3.5 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EGO60959.1 - 5.6e-06 26.4 0.0 4.4e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGO60959.1 - 0.037 13.8 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 tRNA_int_endo PF01974.17 EGO60960.1 - 9.8e-19 67.2 0.0 2.3e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EGO60960.1 - 3.5e-05 23.4 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Methyltransf_PK PF05891.12 EGO60961.1 - 3.6e-90 301.3 0.0 4.1e-90 301.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EGO60961.1 - 0.00019 22.0 0.0 0.00036 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO60961.1 - 0.00044 20.1 0.0 0.0013 18.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO60961.1 - 0.0052 17.5 0.0 0.0085 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO60961.1 - 0.0066 17.1 0.0 0.013 16.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGO60961.1 - 0.037 13.3 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain CitG PF01874.16 EGO60961.1 - 0.059 13.0 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase Pkinase PF00069.25 EGO60962.1 - 6.7e-08 32.2 0.0 8.4e-07 28.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGO60962.1 - 0.038 13.9 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family PEGSRP PF07623.11 EGO60962.1 - 0.13 12.1 2.2 0.27 11.1 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) Pkinase_Tyr PF07714.17 EGO60962.1 - 0.2 10.9 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase PBP PF01161.20 EGO60963.1 - 1.3e-14 54.7 0.0 1.8e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Erythro_esteras PF05139.14 EGO60964.1 - 4.2e-121 405.0 4.5 4.8e-121 404.8 4.5 1.0 1 0 0 1 1 1 1 Erythromycin esterase Acetyltransf_3 PF13302.7 EGO60964.1 - 0.54 10.9 4.4 3.1 8.5 0.2 3.2 2 2 1 3 3 3 0 Acetyltransferase (GNAT) domain Con-6 PF10346.9 EGO60965.1 - 3.8e-26 90.8 8.7 4.5e-13 49.0 0.1 2.9 3 0 0 3 3 3 2 Conidiation protein 6 SpoIIIAH PF12685.7 EGO60965.1 - 0.31 10.8 11.6 0.51 10.1 8.5 2.2 1 1 1 2 2 2 0 SpoIIIAH-like protein Macoilin PF09726.9 EGO60965.1 - 2.8 6.4 10.1 3.3 6.1 10.1 1.1 1 0 0 1 1 1 0 Macoilin family SMP PF04927.12 EGO60966.1 - 3.1e-18 66.0 6.3 3.9e-15 56.1 0.8 2.1 2 0 0 2 2 2 2 Seed maturation protein Ifi-6-16 PF06140.13 EGO60966.1 - 0.0086 16.0 0.0 1.5 8.8 0.0 2.1 2 0 0 2 2 2 2 Interferon-induced 6-16 family Mito_fiss_reg PF05308.11 EGO60966.1 - 0.01 15.9 2.8 0.012 15.8 2.8 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator IF-2 PF11987.8 EGO60966.1 - 0.076 13.1 0.3 0.12 12.5 0.3 1.4 1 1 0 1 1 1 0 Translation-initiation factor 2 adh_short PF00106.25 EGO60967.1 - 2e-25 89.4 0.0 3.9e-21 75.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO60967.1 - 3.7e-19 69.2 0.0 5.7e-16 58.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO60967.1 - 9.6e-10 38.7 0.1 1.8e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO60967.1 - 0.00083 18.9 0.0 0.0025 17.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EGO60967.1 - 0.037 13.9 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGO60967.1 - 0.068 12.5 0.1 0.17 11.2 0.1 1.6 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EGO60967.1 - 0.12 11.6 0.3 0.22 10.7 0.3 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RmlD_sub_bind PF04321.17 EGO60967.1 - 0.13 11.3 0.1 2.5 7.1 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain FAD_binding_3 PF01494.19 EGO60967.1 - 0.16 11.1 0.1 0.27 10.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EGO60967.1 - 0.19 12.3 0.3 0.32 11.6 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGO60968.1 - 7.9e-35 121.0 0.0 4e-34 118.7 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGO60968.1 - 6.4e-06 26.3 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO60968.1 - 0.0071 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGO60968.1 - 0.029 13.6 0.4 0.046 13.0 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 EGO60968.1 - 0.21 10.6 0.1 0.3 10.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Peptidase_C48 PF02902.19 EGO60969.1 - 2.2e-11 44.0 14.8 1.4e-06 28.3 0.2 4.2 4 0 0 4 4 4 3 Ulp1 protease family, C-terminal catalytic domain DEAD PF00270.29 EGO60970.1 - 3.7e-42 144.1 0.0 7.3e-42 143.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGO60970.1 - 3.6e-22 78.8 0.0 2.6e-21 76.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO60970.1 - 6e-06 26.4 0.0 9.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGO60970.1 - 0.0071 16.7 0.0 0.022 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGO60970.1 - 0.0073 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 EGO60970.1 - 0.0079 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase UvrD-helicase PF00580.21 EGO60970.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Pro_CA PF00484.19 EGO60971.1 - 4.8e-06 27.0 0.0 7.8e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Carbonic anhydrase 60KD_IMP PF02096.20 EGO60972.1 - 3.2e-17 62.9 3.4 4.9e-17 62.3 3.4 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein BCAS3 PF12490.8 EGO60972.1 - 0.34 10.4 3.2 7.2 6.1 0.3 2.2 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 3 TOM13 PF08219.11 EGO60973.1 - 2.8e-36 123.3 0.0 3.7e-36 123.0 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.13 EGO60974.1 - 1.9e-22 79.6 0.0 3.8e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.6 EGO60974.1 - 1.6e-12 47.0 0.8 2.6e-12 46.3 0.8 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EGO60974.1 - 1.7e-09 37.7 0.0 3.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.13 EGO60974.1 - 0.016 14.8 0.1 0.03 14.0 0.1 1.4 1 0 0 1 1 1 0 TAP C-terminal domain DUF3246 PF11596.8 EGO60974.1 - 2.6 7.4 5.9 0.96 8.8 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Gtr1_RagA PF04670.12 EGO60975.1 - 1.4e-97 325.7 0.0 2e-97 325.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EGO60975.1 - 5.2e-09 36.4 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO60975.1 - 5.4e-09 35.7 0.1 8.1e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGO60975.1 - 3.1e-08 33.4 0.0 5.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGO60975.1 - 1.6e-07 31.4 0.0 2.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO60975.1 - 0.00017 21.6 1.0 0.02 14.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase G-alpha PF00503.20 EGO60975.1 - 0.0017 17.6 2.5 0.59 9.2 0.7 2.6 2 1 1 3 3 3 2 G-protein alpha subunit AAA_29 PF13555.6 EGO60975.1 - 0.0034 17.1 0.4 0.032 14.0 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 EGO60975.1 - 0.0074 15.5 0.1 0.016 14.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 EGO60975.1 - 0.012 16.2 0.1 0.022 15.2 0.1 1.4 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 EGO60975.1 - 0.053 13.2 0.1 0.089 12.5 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 EGO60975.1 - 0.15 11.5 0.0 0.5 9.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region SPESP1 PF15754.5 EGO60975.1 - 0.22 10.7 0.1 0.38 9.9 0.1 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Ank_2 PF12796.7 EGO60976.1 - 5.2e-36 123.1 16.9 1e-09 38.8 0.1 10.2 5 3 7 12 12 12 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO60976.1 - 5.8e-18 63.1 16.9 0.0072 16.8 0.0 12.5 14 1 1 15 15 15 4 Ankyrin repeat Ank_4 PF13637.6 EGO60976.1 - 2.9e-16 59.6 17.0 5e-07 30.1 0.0 11.3 12 2 0 12 12 12 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGO60976.1 - 1.8e-12 47.2 11.8 8.4e-05 22.8 0.0 8.1 8 2 2 10 10 10 4 Ankyrin repeats (many copies) Ank PF00023.30 EGO60976.1 - 9.5e-12 44.8 28.1 0.033 14.6 0.0 11.2 12 1 1 13 13 13 4 Ankyrin repeat Zn_clus PF00172.18 EGO60977.1 - 1.3e-07 31.6 11.0 3e-07 30.5 11.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EGO60979.1 - 2.3e-44 151.8 53.3 3.2e-43 148.0 53.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO60979.1 - 7.3e-11 41.6 28.6 1.6e-09 37.2 19.0 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter FAD_binding_4 PF01565.23 EGO60980.1 - 3.3e-18 65.8 0.5 6e-18 64.9 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGO60980.1 - 6.3e-11 42.2 0.1 1.4e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Metallophos PF00149.28 EGO60982.1 - 6.6e-10 39.8 0.1 1.2e-09 38.9 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGO60982.1 - 6.3e-08 33.0 1.3 1.4e-06 28.6 1.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Transp_inhibit PF18791.1 EGO60982.1 - 0.15 11.6 1.5 0.17 11.4 0.1 1.7 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain adh_short_C2 PF13561.6 EGO60983.1 - 1.2e-49 169.0 0.8 8.9e-47 159.6 0.8 2.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO60983.1 - 2.9e-44 150.9 0.3 3.4e-42 144.1 0.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO60983.1 - 2.2e-12 47.3 0.1 3.8e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO60983.1 - 0.0012 18.4 0.0 0.0041 16.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family IMUP PF15761.5 EGO60983.1 - 1.4 9.6 7.6 2.8 8.7 7.6 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 EGO60983.1 - 1.8 8.1 7.1 2.9 7.5 7.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ank_2 PF12796.7 EGO60984.1 - 4.7e-09 36.7 0.1 0.0044 17.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGO60984.1 - 5.7e-09 35.5 0.1 0.014 15.8 0.0 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 EGO60984.1 - 3.6e-07 30.6 0.1 0.00018 22.0 0.0 4.2 3 1 2 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 EGO60984.1 - 7.3e-07 29.4 0.5 0.14 12.6 0.0 5.3 6 0 0 6 6 6 2 Ankyrin repeat F-box-like_2 PF13013.6 EGO60984.1 - 0.005 16.8 1.1 0.01 15.8 0.1 2.1 2 0 0 2 2 2 1 F-box-like domain Ank_5 PF13857.6 EGO60984.1 - 0.011 16.1 0.2 0.71 10.3 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeats (many copies) F-box PF00646.33 EGO60984.1 - 0.027 14.3 0.1 0.064 13.2 0.1 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EGO60984.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like Ank_2 PF12796.7 EGO60985.1 - 4.2e-08 33.7 0.0 5.4e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGO60985.1 - 1.4e-07 31.9 0.5 0.00022 21.7 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGO60985.1 - 2.1e-07 31.1 0.8 0.0022 18.4 0.1 3.5 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGO60985.1 - 1.8e-06 27.8 0.4 0.52 11.0 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGO60985.1 - 3.5e-05 24.0 0.1 0.00045 20.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) NAD_binding_8 PF13450.6 EGO60986.1 - 7.3e-09 35.7 0.0 2.5e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGO60986.1 - 6.4e-08 32.3 0.4 0.002 17.5 0.0 3.4 2 1 0 3 3 3 3 Flavin containing amine oxidoreductase DAO PF01266.24 EGO60986.1 - 6.6e-05 22.7 0.1 0.027 14.1 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase RE_Bsp6I PF09504.10 EGO60986.1 - 0.02 14.5 0.2 0.039 13.5 0.2 1.4 1 0 0 1 1 1 0 Bsp6I restriction endonuclease DUF3860 PF12976.7 EGO60986.1 - 0.08 13.0 0.1 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) p450 PF00067.22 EGO60990.1 - 2.6e-93 313.3 0.0 3.3e-93 313.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ParA PF10609.9 EGO60992.1 - 1.5e-91 306.2 0.0 2e-91 305.8 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGO60992.1 - 3.6e-10 40.0 0.0 7.2e-10 39.0 0.0 1.5 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EGO60992.1 - 1.2e-06 28.0 0.0 1.9e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 EGO60992.1 - 8.6e-06 25.8 0.0 0.00066 19.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 EGO60992.1 - 7.4e-05 22.1 0.3 7.4e-05 22.1 0.3 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 EGO60992.1 - 0.0015 17.5 0.5 0.0023 16.9 0.5 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 EGO60992.1 - 0.0051 16.4 0.4 0.0093 15.6 0.4 1.4 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 EGO60992.1 - 0.021 14.3 0.4 0.05 13.1 0.4 1.7 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 EGO60992.1 - 0.03 14.2 0.8 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EGO60992.1 - 0.061 13.2 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 EGO60992.1 - 0.14 12.1 1.3 0.36 10.7 1.3 1.6 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 EGO60992.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EGO60992.1 - 0.37 11.2 1.4 0.53 10.6 0.6 1.6 2 0 0 2 2 2 0 AAA ATPase domain SAM_decarbox PF01536.16 EGO60993.1 - 1.9e-132 441.6 0.0 2.2e-132 441.4 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TFIIA PF03153.13 EGO60994.1 - 9.3 6.1 25.4 11 5.9 25.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_8 PF13855.6 EGO60995.1 - 1.3 8.8 3.5 5.9 6.7 0.0 3.4 3 1 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 EGO60995.1 - 3.5 8.2 8.4 19 5.9 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Glyco_hydro_64 PF16483.5 EGO60996.1 - 1.8e-109 366.5 0.0 1.1e-67 228.9 0.0 2.1 2 0 0 2 2 2 2 Beta-1,3-glucanase 2-Hacid_dh_C PF02826.19 EGO60998.1 - 2.7e-38 131.1 0.0 4.6e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EGO60998.1 - 1.2e-07 32.0 0.0 2.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGO60998.1 - 0.023 15.3 0.0 0.063 13.9 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Striatin PF08232.12 EGO60999.1 - 1.3 9.6 6.4 0.16 12.5 0.9 2.0 1 1 1 2 2 2 0 Striatin family Pneumo_att_G PF05539.11 EGO60999.1 - 3 7.3 9.3 4.3 6.8 9.3 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G bZIP_1 PF00170.21 EGO61002.1 - 0.0018 18.3 9.3 0.0018 18.3 9.3 2.9 3 0 0 3 3 3 1 bZIP transcription factor DUF3235 PF11574.8 EGO61002.1 - 0.043 14.7 0.2 0.1 13.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) bZIP_2 PF07716.15 EGO61002.1 - 0.13 12.3 9.1 0.49 10.5 9.1 1.9 1 0 0 1 1 1 0 Basic region leucine zipper Aldolase_II PF00596.21 EGO61004.1 - 5.5e-45 153.6 0.1 7.2e-45 153.2 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain 2OG-Fe_Oxy_2 PF10014.9 EGO61005.1 - 2.6e-53 180.7 0.3 3.3e-53 180.3 0.3 1.1 1 0 0 1 1 1 1 2OG-Fe dioxygenase 2OG-FeII_Oxy_3 PF13640.6 EGO61005.1 - 0.086 13.7 0.1 1.9 9.4 0.0 2.3 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Pept_tRNA_hydro PF01195.19 EGO61006.1 - 3.8e-28 98.6 0.0 4.8e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase BAR PF03114.18 EGO61007.1 - 6.1e-69 232.3 3.5 8.1e-69 231.9 3.5 1.2 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 EGO61007.1 - 0.004 17.9 0.6 0.028 15.1 0.0 2.7 3 1 0 3 3 3 1 CP12 domain SVIP PF15811.5 EGO61007.1 - 0.53 10.8 4.3 0.24 11.9 0.6 2.2 2 0 0 2 2 2 0 Small VCP/p97-interacting protein BAR PF03114.18 EGO61008.1 - 5.4e-64 216.1 4.1 6.7e-64 215.8 4.1 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 EGO61008.1 - 1.2e-06 28.0 1.3 1.7e-06 27.4 1.3 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF3086 PF11285.8 EGO61008.1 - 0.028 13.5 1.5 0.047 12.8 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) PMEI PF04043.15 EGO61008.1 - 0.063 13.6 1.8 0.14 12.5 1.8 1.6 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Uds1 PF15456.6 EGO61008.1 - 0.49 10.6 5.1 1.1 9.4 5.1 1.7 1 0 0 1 1 1 0 Up-regulated During Septation DUF4164 PF13747.6 EGO61008.1 - 2.9 8.2 8.9 6.1 7.2 8.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Cyclin_C_2 PF16899.5 EGO61009.1 - 3.5e-35 120.5 0.0 3.6e-32 110.9 0.0 2.6 3 0 0 3 3 3 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EGO61009.1 - 0.00024 20.8 0.0 0.00067 19.4 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Stn1 PF10451.9 EGO61009.1 - 0.13 11.2 0.0 0.3 10.0 0.0 1.5 2 0 0 2 2 2 0 Telomere regulation protein Stn1 Amino_oxidase PF01593.24 EGO61010.1 - 9.9e-84 282.2 0.0 1.2e-83 281.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGO61010.1 - 9.9e-09 35.3 0.0 2.8e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO61010.1 - 2.8e-07 30.5 0.0 0.0002 21.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGO61010.1 - 0.0018 17.6 0.0 0.02 14.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGO61010.1 - 0.011 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EGO61010.1 - 0.083 11.6 0.4 0.13 10.9 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EGO61010.1 - 0.14 11.3 0.3 0.28 10.4 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Ammonium_transp PF00909.21 EGO61011.1 - 1.9e-120 402.3 27.5 2.1e-120 402.1 27.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TMEM107 PF14995.6 EGO61011.1 - 2.3 8.6 8.9 0.87 10.0 0.7 3.2 3 0 0 3 3 3 0 Transmembrane protein Con-6 PF10346.9 EGO61012.1 - 9e-16 57.6 0.5 1.2e-14 54.0 0.4 2.3 2 0 0 2 2 2 1 Conidiation protein 6 AltA1 PF16541.5 EGO61013.1 - 5.1e-28 98.1 1.5 5.1e-28 98.1 1.5 1.5 2 0 0 2 2 2 1 Alternaria alternata allergen 1 DUF1996 PF09362.10 EGO61015.1 - 2.6e-84 282.9 1.0 3.1e-84 282.6 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DLH PF01738.18 EGO61016.1 - 6.1e-16 58.6 0.1 2.6e-15 56.6 0.1 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EGO61016.1 - 0.017 14.6 0.1 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Rubrerythrin PF02915.17 EGO61016.1 - 0.035 14.5 0.1 0.06 13.7 0.1 1.4 1 0 0 1 1 1 0 Rubrerythrin Glyco_hydro_47 PF01532.20 EGO61018.1 - 2.5e-159 531.1 0.0 2.2e-157 524.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 EGO61018.1 - 0.022 13.8 0.0 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 F-box-like PF12937.7 EGO61019.1 - 0.00014 21.6 0.1 0.00032 20.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like APOBEC3 PF18771.1 EGO61019.1 - 0.098 12.8 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 APOBEC3 APOBEC_C PF05240.14 EGO61019.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 APOBEC-like C-terminal domain TauD PF02668.16 EGO61020.1 - 2.3e-32 112.8 0.1 3.4e-32 112.3 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LssY_C PF14067.6 EGO61020.1 - 0.033 13.7 0.0 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 LssY C-terminus DUF3328 PF11807.8 EGO61021.1 - 1.3e-11 44.7 0.5 1.4e-11 44.6 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EGO61022.1 - 9.9e-07 28.8 0.0 9.9e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) zinc_ribbon_2 PF13240.6 EGO61023.1 - 0.087 12.6 0.2 0.087 12.6 0.2 2.8 4 0 0 4 4 4 0 zinc-ribbon domain GFA PF04828.14 EGO61023.1 - 0.094 13.1 0.1 0.094 13.1 0.1 2.4 4 0 0 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme HCV_NS5a_1a PF08300.13 EGO61023.1 - 0.68 10.1 0.1 0.68 10.1 0.1 3.1 4 0 0 4 4 4 0 Hepatitis C virus non-structural 5a zinc finger domain Chromate_transp PF02417.15 EGO61024.1 - 8e-60 201.5 28.6 5.3e-34 117.6 13.7 2.4 2 0 0 2 2 2 2 Chromate transporter TFIIA_gamma_C PF02751.14 EGO61025.1 - 6.8e-10 38.9 0.1 2.8e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 EGO61025.1 - 1.3e-09 37.9 0.4 0.0001 22.2 0.1 2.4 2 0 0 2 2 2 2 Transcription initiation factor IIA, gamma subunit, helical domain DUF3328 PF11807.8 EGO61028.1 - 3.8e-61 206.7 3.8 4.6e-61 206.4 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_61 PF03443.14 EGO61029.1 - 2.9e-58 197.2 0.1 3.4e-58 197.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fasciclin PF02469.22 EGO61030.1 - 4e-31 107.9 0.0 2.9e-17 63.1 0.5 3.4 2 2 0 2 2 2 2 Fasciclin domain TFIIE-A_C PF11521.8 EGO61030.1 - 5.8 7.3 7.2 1.2 9.5 2.9 2.1 2 1 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha RhoGAP PF00620.27 EGO61032.1 - 0.00086 19.2 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain DUF4232 PF14016.6 EGO61032.1 - 0.017 15.3 0.4 0.23 11.6 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4232) Swi5 PF07061.11 EGO61033.1 - 1.5e-19 69.9 1.8 1.9e-19 69.5 0.3 2.0 2 0 0 2 2 2 1 Swi5 DCP1 PF06058.13 EGO61033.1 - 2.2e-18 66.3 0.0 3.9e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Dcp1-like decapping family DUF5339 PF17274.2 EGO61033.1 - 0.41 11.5 2.8 0.35 11.7 0.8 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5339) Ribonuclease PF00545.20 EGO61034.1 - 7e-08 33.1 0.1 9.5e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 ribonuclease DUF3433 PF11915.8 EGO61035.1 - 4.2e-37 126.5 17.3 5.8e-20 71.5 1.4 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) S8_pro-domain PF16470.5 EGO61035.1 - 0.25 12.1 2.1 0.78 10.6 0.2 2.6 3 0 0 3 3 3 0 Peptidase S8 pro-domain Ras PF00071.22 EGO61037.1 - 9.5e-16 57.8 0.1 2.9e-07 30.2 0.0 2.9 2 1 0 2 2 2 2 Ras family NACHT PF05729.12 EGO61037.1 - 5.6e-05 23.1 0.0 8.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Roc PF08477.13 EGO61037.1 - 0.00013 22.2 0.0 0.00072 19.8 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGO61037.1 - 0.00023 20.5 0.0 0.00036 19.8 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit TniB PF05621.11 EGO61037.1 - 0.00048 19.6 0.0 0.00079 18.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein Arf PF00025.21 EGO61037.1 - 0.00087 18.8 0.0 0.0037 16.7 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_28 PF13521.6 EGO61037.1 - 0.0048 17.2 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGO61037.1 - 0.0053 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGO61037.1 - 0.0068 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGO61037.1 - 0.0088 16.4 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 EGO61037.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 EGO61037.1 - 0.017 15.6 0.1 0.16 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGO61037.1 - 0.044 13.8 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 EGO61037.1 - 0.07 12.0 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 EGO61037.1 - 0.08 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 EGO61037.1 - 0.083 12.6 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 EGO61037.1 - 0.097 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 EGO61037.1 - 0.099 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EGO61037.1 - 0.12 12.2 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 EGO61037.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 EGO61037.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 EGO61037.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Septin Rad17 PF03215.15 EGO61037.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Peptidase_M48 PF01435.18 EGO61038.1 - 1.9e-46 158.3 0.0 3.1e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Beta-lactamase PF00144.24 EGO61040.1 - 7e-39 134.0 0.1 1.1e-38 133.4 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase TRP PF06011.12 EGO61041.1 - 5.2e-157 523.0 27.9 6.4e-157 522.7 27.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EGO61041.1 - 5.6e-41 140.2 0.3 1.1e-40 139.2 0.3 1.5 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 EGO61041.1 - 0.0084 16.5 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 1 ML domain YesK PF14150.6 EGO61041.1 - 0.066 13.4 0.4 0.066 13.4 0.4 2.6 2 1 0 2 2 2 0 YesK-like protein 5TM-5TMR_LYT PF07694.12 EGO61041.1 - 0.18 11.3 11.9 0.094 12.2 8.2 2.3 2 0 0 2 2 2 0 5TMR of 5TMR-LYT FAM199X PF15814.5 EGO61044.1 - 0.0032 16.6 5.5 0.0032 16.6 5.5 2.3 2 0 0 2 2 2 1 Protein family FAM199X RAP1 PF07218.11 EGO61044.1 - 6.1 5.0 9.0 5.2 5.2 1.7 2.0 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) MPLKIP PF15502.6 EGO61045.1 - 0.027 14.7 0.6 1 9.7 0.0 2.1 2 0 0 2 2 2 0 M-phase-specific PLK1-interacting protein AIM5 PF17050.5 EGO61050.1 - 1.3e-20 74.0 2.6 3.8e-20 72.5 2.6 1.9 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 ECH_1 PF00378.20 EGO61050.1 - 2.5 7.3 11.1 0.16 11.3 3.0 2.4 2 1 1 3 3 3 0 Enoyl-CoA hydratase/isomerase Ribosomal_L17 PF01196.19 EGO61051.1 - 9.5e-32 109.8 0.1 1.6e-31 109.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Mn_catalase PF05067.12 EGO61051.1 - 0.006 15.6 0.0 0.0094 15.0 0.0 1.3 1 0 0 1 1 1 1 Manganese containing catalase UTP25 PF06862.12 EGO61052.1 - 1.2e-204 680.5 1.1 1.5e-204 680.2 1.1 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EGO61052.1 - 0.0022 17.8 0.0 0.099 12.4 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase MitMem_reg PF13012.6 EGO61053.1 - 1.9e-18 66.9 0.6 3.2e-18 66.2 0.2 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGO61053.1 - 4.4e-17 62.1 0.0 7.5e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RPW8 PF05659.11 EGO61053.1 - 0.064 12.9 0.0 0.17 11.5 0.0 1.6 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 SUZ PF12752.7 EGO61054.1 - 4.3e-15 56.2 7.5 4.3e-15 56.2 7.5 3.2 2 1 1 3 3 3 1 SUZ domain R3H PF01424.22 EGO61054.1 - 2.2e-06 27.5 0.1 5.1e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 R3H domain TFIIE-A_C PF11521.8 EGO61054.1 - 2.5 8.5 5.2 8.3 6.8 0.1 2.8 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha zf-CCHC_3 PF13917.6 EGO61055.1 - 2.7e-09 36.8 0.1 6.1e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle cwf18 PF08315.12 EGO61056.1 - 4.2e-46 157.0 7.9 4.2e-46 157.0 7.9 2.0 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor KicB PF03882.14 EGO61056.1 - 6.1 7.1 7.5 0.31 11.2 0.6 2.1 2 1 0 2 2 2 0 MukF winged-helix domain PPR_2 PF13041.6 EGO61057.1 - 1.6e-20 73.0 0.0 3.1e-09 36.9 0.0 4.4 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.6 EGO61057.1 - 1.1e-13 51.1 0.0 3.6e-06 26.9 0.0 4.0 4 1 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGO61057.1 - 3.9e-13 48.9 0.0 1e-06 28.3 0.0 4.5 4 0 0 4 4 4 2 PPR repeat PPR PF01535.20 EGO61057.1 - 2.2e-08 33.8 0.6 0.011 16.0 0.0 5.0 4 1 0 4 4 4 2 PPR repeat PPR_long PF17177.4 EGO61057.1 - 5.3e-05 22.7 0.0 0.016 14.6 0.0 2.4 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP GreA_GreB_N PF03449.15 EGO61057.1 - 0.38 10.9 7.5 0.14 12.3 4.1 2.1 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal Acyl_transf_3 PF01757.22 EGO61058.1 - 6.6e-38 130.6 26.0 5.7e-27 94.7 13.5 2.3 2 1 0 2 2 2 2 Acyltransferase family ALAD PF00490.21 EGO61059.1 - 7.9e-121 403.1 0.0 1.1e-120 402.6 0.0 1.2 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Y_phosphatase3 PF13350.6 EGO61062.1 - 4.9e-45 154.3 0.0 6.6e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EGO61062.1 - 0.0033 17.0 0.0 0.0045 16.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGO61062.1 - 0.0041 16.7 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGO61062.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate DSPc PF00782.20 EGO61062.1 - 0.22 11.4 0.0 0.55 10.0 0.0 1.6 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Phage_holin_3_6 PF07332.11 EGO61063.1 - 0.019 15.0 13.1 0.37 10.8 2.7 3.7 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3141 PF11339.8 EGO61063.1 - 0.5 8.7 2.9 0.75 8.2 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) S4 PF01479.25 EGO61064.1 - 9.2e-12 44.5 0.1 3.2e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 EGO61064.1 - 5.6e-10 40.0 2.2 9.4e-10 39.3 1.7 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Herpes_LAMP2 PF06126.11 EGO61064.1 - 0.05 12.2 0.2 0.057 12.0 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 THDPS_N_2 PF14805.6 EGO61064.1 - 0.089 13.0 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Ribosomal_S18 PF01084.20 EGO61065.1 - 2.2e-10 40.6 0.0 6.6e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S18 PPR_2 PF13041.6 EGO61066.1 - 0.003 17.7 1.8 62 3.9 0.1 5.8 5 1 1 6 6 6 1 PPR repeat family PPR PF01535.20 EGO61066.1 - 0.035 14.3 6.3 1.4 9.4 0.0 5.0 6 0 0 6 6 6 0 PPR repeat FTA4 PF13093.6 EGO61067.1 - 3.1e-69 232.9 0.0 3.5e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 PEARLI-4 PF05278.12 EGO61067.1 - 0.86 9.1 3.9 0.24 10.9 0.2 1.8 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) ZapB PF06005.12 EGO61067.1 - 2.2 8.8 7.4 35 4.9 3.7 3.1 2 1 0 2 2 2 0 Cell division protein ZapB DUF4611 PF15387.6 EGO61067.1 - 5.8 7.2 7.8 6.4 7.1 2.5 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4611) Cep57_MT_bd PF06657.13 EGO61067.1 - 6.6 7.3 9.3 8 7.0 0.6 3.4 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 PS_Dcarbxylase PF02666.15 EGO61068.1 - 1.7e-57 194.2 0.0 2.6e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EGO61068.1 - 8.7e-43 144.8 0.0 7.9e-21 74.3 0.0 2.8 2 0 0 2 2 2 2 C2 domain EF-hand_5 PF13202.6 EGO61068.1 - 0.024 14.1 0.0 0.064 12.8 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 EGO61068.1 - 0.028 14.9 0.3 0.21 12.0 0.4 2.3 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 EGO61068.1 - 0.04 13.5 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EGO61068.1 - 0.062 13.3 0.0 0.24 11.4 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain CEP76-C2 PF15627.6 EGO61068.1 - 0.12 11.9 0.0 15 5.1 0.0 2.4 2 0 0 2 2 2 0 CEP76 C2 domain Coatomer_E PF04733.14 EGO61070.1 - 4.9e-57 193.6 6.0 5.5e-57 193.4 6.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 EGO61070.1 - 1.2e-07 32.2 30.5 0.00037 20.9 1.2 4.2 5 1 0 5 5 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO61070.1 - 2.7e-05 24.3 1.2 0.51 10.6 0.1 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EGO61070.1 - 3.3e-05 23.8 1.4 0.63 10.4 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGO61070.1 - 0.00062 19.5 2.0 0.41 10.5 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGO61070.1 - 0.0009 19.7 12.4 0.5 11.1 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 EGO61070.1 - 0.0046 17.4 22.9 0.12 13.0 0.5 5.6 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGO61070.1 - 0.0067 17.2 22.2 0.022 15.5 0.2 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGO61070.1 - 0.012 15.7 0.0 0.012 15.7 0.0 6.5 8 0 0 8 8 7 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 EGO61070.1 - 0.029 14.4 4.6 0.96 9.5 0.0 3.7 1 1 2 4 4 4 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_12 PF13424.6 EGO61070.1 - 0.031 14.6 18.1 0.57 10.5 1.0 5.2 3 3 2 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGO61070.1 - 1.3 9.3 6.6 0.44 10.7 0.2 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGO61070.1 - 2.2 8.1 10.4 1.6 8.5 0.2 4.9 6 0 0 6 6 6 0 TPR repeat TPR_16 PF13432.6 EGO61070.1 - 7.4 7.3 30.4 0.32 11.7 0.4 4.9 6 2 0 6 6 5 0 Tetratricopeptide repeat DUF2462 PF09495.10 EGO61071.1 - 4.9e-12 46.4 13.2 6.8e-12 45.9 13.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) RFXA_RFXANK_bdg PF15289.6 EGO61071.1 - 0.088 13.1 3.0 0.11 12.9 3.0 1.1 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain PepX_C PF08530.10 EGO61072.1 - 8.8e-52 176.3 0.2 1.8e-51 175.3 0.0 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 EGO61072.1 - 3.4e-37 128.5 0.3 5.4e-37 127.8 0.3 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EGO61072.1 - 0.0059 15.9 0.0 0.0095 15.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Med5 PF08689.10 EGO61075.1 - 3.8e-75 253.5 0.0 5.6e-74 249.7 0.0 2.6 1 1 0 1 1 1 1 Mediator complex subunit Med5 FMN_dh PF01070.18 EGO61076.1 - 1.1e-115 386.4 0.0 1.4e-115 386.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 EGO61076.1 - 0.00035 20.1 0.5 0.00059 19.3 0.5 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 EGO61076.1 - 0.00041 19.6 0.4 0.0011 18.2 0.2 1.8 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 EGO61076.1 - 0.0015 17.6 1.8 0.0077 15.3 1.8 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 EGO61076.1 - 0.0043 16.4 0.4 0.91 8.8 0.1 2.5 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 EGO61076.1 - 0.03 13.5 1.1 0.83 8.8 0.0 2.3 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF1269 PF06897.12 EGO61076.1 - 0.071 13.4 0.7 0.67 10.3 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) DEC-1_N PF04625.13 EGO61076.1 - 0.15 11.0 0.2 0.25 10.3 0.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF4202 PF13875.6 EGO61077.1 - 1.9e-45 155.0 0.1 2.1e-45 154.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Peptidase_M16 PF00675.20 EGO61077.1 - 0.017 15.1 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) P53_TAD PF08563.11 EGO61077.1 - 0.11 12.0 0.5 0.22 11.1 0.5 1.4 1 0 0 1 1 1 0 P53 transactivation motif VP_N-CPKC PF11475.8 EGO61080.1 - 0.17 11.8 0.5 0.17 11.8 0.5 1.7 2 0 0 2 2 2 0 Virion protein N terminal domain 14-3-3 PF00244.20 EGO61081.1 - 2.9e-08 33.5 0.6 2e-07 30.7 0.1 2.0 2 0 0 2 2 2 1 14-3-3 protein Kin17_mid PF10357.9 EGO61082.1 - 7.6e-45 151.9 1.1 1.9e-44 150.6 1.1 1.7 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 EGO61082.1 - 2.1e-05 24.7 5.0 3.9e-05 23.9 5.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGO61082.1 - 0.00084 19.6 4.0 0.002 18.4 4.0 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding PCC_BT PF18140.1 EGO61082.1 - 0.19 12.0 1.5 0.22 11.8 0.1 1.8 2 0 0 2 2 2 0 Propionyl-coenzyme A carboxylase BT domain zf-C2H2_2 PF12756.7 EGO61082.1 - 1.1 9.6 5.7 0.45 10.9 1.3 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Spt4 PF06093.13 EGO61083.1 - 3.6e-32 110.3 0.2 4.4e-32 110.0 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.11 EGO61083.1 - 0.22 11.5 0.5 0.88 9.6 0.1 1.9 1 1 1 2 2 2 0 Coronavirus gene 5 protein AMPK1_CBM PF16561.5 EGO61084.1 - 7.8e-27 93.3 0.0 1.4e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EGO61084.1 - 7.2e-26 90.3 1.9 7.2e-26 90.3 1.9 2.9 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain Peptidase_M22 PF00814.25 EGO61085.1 - 5.5e-83 278.8 0.0 6.6e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family EPL1 PF10513.9 EGO61087.1 - 3.4e-18 66.5 2.3 3.4e-18 66.5 2.3 2.6 3 1 0 3 3 3 1 Enhancer of polycomb-like Erythro_esteras PF05139.14 EGO61087.1 - 0.087 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Erythromycin esterase EF-hand_1 PF00036.32 EGO61088.1 - 4.2e-27 91.6 12.5 2.4e-07 29.8 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGO61088.1 - 4.1e-24 84.8 12.0 3.1e-14 53.2 1.4 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EGO61088.1 - 9.3e-21 71.9 5.7 4.6e-05 23.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGO61088.1 - 1.5e-18 65.3 10.2 1.7e-06 27.2 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGO61088.1 - 5.2e-13 48.6 11.9 0.00013 21.7 0.5 4.2 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGO61088.1 - 2.8e-07 30.8 0.1 0.0015 18.8 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGO61088.1 - 4.1e-06 26.7 8.5 0.0024 17.8 0.5 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EGO61088.1 - 0.029 14.6 0.8 0.12 12.6 0.7 2.2 1 1 0 1 1 1 0 Dockerin type I domain Anillin PF08174.11 EGO61088.1 - 0.068 13.6 0.0 2 8.8 0.0 2.1 1 1 1 2 2 2 0 Cell division protein anillin Squash PF00299.18 EGO61089.1 - 0.074 13.1 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 Squash family serine protease inhibitor Ribosomal_S9 PF00380.19 EGO61095.1 - 3.3e-43 147.0 1.2 7.8e-43 145.8 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S9/S16 PriCT_1 PF08708.11 EGO61095.1 - 0.025 14.3 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) EF1G PF00647.19 EGO61096.1 - 2.7e-44 149.6 0.1 4.9e-44 148.8 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EGO61096.1 - 4.5e-16 58.9 0.1 1.2e-15 57.5 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO61096.1 - 3e-13 49.9 0.4 9.2e-13 48.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGO61096.1 - 1.5e-09 37.7 2.5 2.4e-09 37.1 0.3 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGO61096.1 - 3.9e-07 30.4 0.0 8.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGO61096.1 - 7.6e-07 29.2 0.0 2.2e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGO61096.1 - 0.022 15.1 0.0 0.063 13.6 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 EGO61096.1 - 0.16 12.3 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DEC-1_N PF04625.13 EGO61096.1 - 2.5 7.0 10.0 4.7 6.1 10.0 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region NIF PF03031.18 EGO61097.1 - 3e-23 82.3 0.0 4.6e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RRP36 PF06102.12 EGO61098.1 - 6e-55 185.7 25.8 6e-55 185.7 25.8 2.1 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 BPL_N PF09825.9 EGO61098.1 - 0.5 9.4 6.7 0.84 8.6 6.7 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal RNase_PH_C PF03725.15 EGO61098.1 - 0.69 10.0 2.5 2.4 8.3 2.5 1.9 1 1 0 1 1 1 0 3' exoribonuclease family, domain 2 ABC1 PF03109.16 EGO61099.1 - 1.2e-31 109.3 0.0 3.1e-31 108.0 0.0 1.7 1 0 0 1 1 1 1 ABC1 family PIEZO PF15917.5 EGO61099.1 - 0.22 11.0 4.1 0.44 10.0 4.1 1.4 1 0 0 1 1 1 0 Piezo DUF1840 PF08895.11 EGO61099.1 - 1.4 9.3 7.6 17 5.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) DUF4834 PF16118.5 EGO61099.1 - 5.5 8.0 5.7 12 7.0 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Es2 PF09751.9 EGO61100.1 - 1.7e-127 426.8 9.5 1.7e-127 426.8 9.5 1.4 2 0 0 2 2 2 1 Nuclear protein Es2 Hus1 PF04005.12 EGO61101.1 - 4.8e-78 262.2 0.0 6.4e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein zf-RING_2 PF13639.6 EGO61101.1 - 2.2e-08 34.3 5.4 2.2e-08 34.3 5.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EGO61101.1 - 1.8e-06 27.8 0.7 1.8e-06 27.8 0.7 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGO61101.1 - 2.1e-06 27.5 6.4 5.6e-06 26.1 3.4 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO61101.1 - 1e-05 25.3 4.3 1e-05 25.3 4.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO61101.1 - 3.3e-05 23.7 3.0 8.2e-05 22.5 3.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGO61101.1 - 0.00014 22.1 5.0 0.00014 22.1 5.0 2.0 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGO61101.1 - 0.00025 20.8 6.5 0.0018 18.1 4.8 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO61101.1 - 0.00028 20.7 8.1 0.0098 15.7 3.6 2.7 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGO61101.1 - 0.0072 16.4 3.6 0.021 14.9 3.6 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EGO61101.1 - 0.019 14.7 3.2 0.019 14.7 3.2 3.1 3 0 0 3 3 3 0 RING-like zinc finger zf-Nse PF11789.8 EGO61101.1 - 0.02 14.7 2.6 0.039 13.8 2.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EGO61101.1 - 3.6 7.8 10.9 0.79 9.9 5.8 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Sec16_C PF12931.7 EGO61102.1 - 6.8e-112 374.0 0.0 1e-111 373.4 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 EGO61102.1 - 9.7e-35 119.7 0.7 3.5e-34 117.9 0.0 2.4 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_N PF12935.7 EGO61102.1 - 1.5e-08 35.1 29.4 1.5e-08 35.1 29.4 4.9 3 1 1 4 4 4 1 Vesicle coat trafficking protein Sec16 N-terminus PhoLip_ATPase_C PF16212.5 EGO61103.1 - 2e-51 175.2 8.6 2e-51 175.2 8.6 2.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGO61103.1 - 1.8e-16 59.5 0.3 6.2e-16 57.8 0.3 1.9 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGO61103.1 - 2.8e-14 53.9 0.6 4.9e-08 33.5 0.6 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGO61103.1 - 3.2e-07 30.1 0.2 0.0021 17.6 0.0 2.9 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 EGO61103.1 - 1.5e-05 25.0 0.0 0.00059 19.9 0.0 2.9 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGO61103.1 - 0.0016 18.3 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PHB_acc PF05233.13 EGO61103.1 - 0.13 12.4 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 PHB accumulation regulatory domain Phage_Coat_Gp8 PF05371.12 EGO61103.1 - 1.1 9.1 3.4 3.6 7.4 1.4 2.5 2 0 0 2 2 2 0 Phage major coat protein, Gp8 Suc_Fer-like PF06999.12 EGO61104.1 - 6.9e-62 208.8 0.0 8.8e-62 208.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Methyltransf_31 PF13847.6 EGO61105.1 - 1.3e-05 25.0 0.0 2.8e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO61105.1 - 0.0006 19.4 0.0 0.0029 17.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain AviRa PF11599.8 EGO61105.1 - 0.0041 16.6 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_25 PF13649.6 EGO61105.1 - 0.0061 17.2 0.0 0.013 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO61105.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EGO61105.1 - 0.035 13.4 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EGO61105.1 - 0.038 14.0 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EGO61105.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) N6_Mtase PF02384.16 EGO61105.1 - 0.27 10.5 0.0 0.64 9.2 0.0 1.5 2 0 0 2 2 2 0 N-6 DNA Methylase FAD_binding_6 PF00970.24 EGO61106.1 - 1.5e-08 34.9 0.0 4.3e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGO61106.1 - 0.0011 19.5 0.0 0.005 17.5 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain AA_permease_2 PF13520.6 EGO61107.1 - 2.5e-64 217.7 39.4 3.4e-64 217.3 39.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO61107.1 - 1.7e-27 96.2 28.1 1.7e-27 96.2 28.1 2.0 2 0 0 2 2 2 1 Amino acid permease tRNA-synt_1 PF00133.22 EGO61108.1 - 3e-53 181.0 0.0 2.3e-20 72.4 0.1 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EGO61108.1 - 1.6e-41 141.9 0.0 3.5e-41 140.8 0.0 1.6 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EGO61108.1 - 2e-32 112.4 1.7 1.1e-21 77.1 0.0 4.6 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGO61108.1 - 1.3e-11 44.7 0.0 3e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGO61108.1 - 0.01 15.2 0.0 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EGO61108.1 - 0.06 12.3 0.0 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (K) 2-Hacid_dh_C PF02826.19 EGO61109.1 - 1.7e-53 180.7 0.0 2.4e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGO61109.1 - 1.5e-16 60.2 0.0 2.2e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGO61109.1 - 2.7e-06 27.6 0.0 1.2e-05 25.5 0.0 2.0 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EGO61109.1 - 0.031 14.3 0.0 0.14 12.2 0.0 2.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 EGO61109.1 - 0.05 14.4 0.0 0.19 12.5 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 EGO61109.1 - 0.086 13.3 0.7 6.1 7.3 0.6 3.0 2 1 0 2 2 2 0 Putative NAD(P)-binding DUF3684 PF12449.8 EGO61110.1 - 0 1458.5 0.0 0 1458.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) MMtag PF10159.9 EGO61110.1 - 3.5e-30 104.1 1.7 3.5e-30 104.1 1.7 2.8 3 0 0 3 3 3 1 Multiple myeloma tumor-associated HATPase_c_3 PF13589.6 EGO61110.1 - 0.0001 22.1 0.0 0.00039 20.3 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.10 EGO61110.1 - 0.052 13.6 0.1 0.29 11.2 0.1 2.1 2 0 0 2 2 2 0 WLM domain Reprolysin_5 PF13688.6 EGO61110.1 - 0.077 13.1 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12 Med6 PF04934.14 EGO61111.1 - 3.4e-35 120.8 0.0 4.6e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component HA2 PF04408.23 EGO61112.1 - 9.7e-24 83.7 2.7 2.4e-23 82.5 0.0 2.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGO61112.1 - 1.5e-13 50.9 0.0 2.9e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGO61112.1 - 6.6e-11 42.5 0.0 4.7e-10 39.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGO61112.1 - 1.9e-07 31.0 0.1 1e-06 28.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SSE PF00437.20 EGO61112.1 - 0.011 14.8 0.0 0.034 13.2 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 EGO61112.1 - 0.017 15.4 0.0 0.05 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGO61112.1 - 0.02 14.4 0.1 0.052 13.0 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 EGO61112.1 - 0.024 14.9 1.8 0.6 10.4 1.8 2.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGO61112.1 - 0.071 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGO61112.1 - 0.083 12.2 0.8 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 KaiC FtsK_SpoIIIE PF01580.18 EGO61112.1 - 0.1 12.0 0.0 0.3 10.4 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 EGO61112.1 - 0.42 11.1 0.0 0.42 11.1 0.0 3.4 5 0 0 5 5 4 0 AAA domain SAPS PF04499.15 EGO61112.1 - 3.4 6.4 8.7 6.8 5.4 8.7 1.5 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PAC3 PF10178.9 EGO61113.1 - 1.5e-06 28.2 0.0 2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 PAC4 PF16093.5 EGO61113.1 - 0.015 15.5 0.1 0.023 14.9 0.1 1.3 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Ribosomal_L27A PF00828.19 EGO61114.1 - 3.7e-21 76.1 0.0 6.3e-21 75.4 0.0 1.4 1 1 1 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Cyclase PF04199.13 EGO61115.1 - 2.1e-07 31.2 0.0 3.5e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Putative cyclase Metallophos PF00149.28 EGO61117.1 - 1.2e-38 133.6 0.1 2.5e-38 132.7 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short_C2 PF13561.6 EGO61118.1 - 3e-43 148.1 1.6 6.3e-43 147.0 1.6 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO61118.1 - 2.9e-36 124.8 1.2 2.1e-35 122.0 1.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGO61118.1 - 9.4e-08 32.2 0.7 4.9e-07 29.8 0.7 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGO61118.1 - 0.0069 15.9 0.1 0.42 10.0 0.0 2.4 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EGO61118.1 - 0.023 14.6 0.2 0.037 13.9 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mrr_cat PF04471.12 EGO61118.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease 2-Hacid_dh_C PF02826.19 EGO61118.1 - 0.085 12.2 0.6 0.11 11.8 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TauD PF02668.16 EGO61119.1 - 1.4e-33 116.8 0.0 2.1e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EGO61119.1 - 3.5e-15 56.4 0.0 7.3e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) PhoD PF09423.10 EGO61120.1 - 1.4e-46 159.1 0.1 2.6e-46 158.3 0.1 1.4 1 1 0 1 1 1 1 PhoD-like phosphatase EMP24_GP25L PF01105.24 EGO61121.1 - 1.6e-46 158.5 2.8 1.8e-46 158.4 2.8 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SKIP_SNW PF02731.15 EGO61122.1 - 1.5e-71 239.3 5.7 1.5e-71 239.3 5.7 2.4 2 0 0 2 2 2 1 SKIP/SNW domain Tim17 PF02466.19 EGO61123.1 - 5.1e-41 139.5 6.2 8.1e-41 138.9 6.2 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.12 EGO61123.1 - 0.00051 20.0 0.1 0.095 12.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF543) USP7_ICP0_bdg PF12436.8 EGO61125.1 - 1.5e-89 299.4 0.7 2.8e-87 292.0 0.1 3.1 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EGO61125.1 - 1.5e-73 246.9 4.7 1.2e-71 240.7 1.6 3.7 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 EGO61125.1 - 4.6e-43 147.6 1.2 6.2e-35 120.9 0.0 2.6 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGO61125.1 - 6.9e-21 75.2 0.2 1.7e-12 47.6 0.0 2.4 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EGO61125.1 - 3.5e-10 40.0 0.0 1.1e-09 38.4 0.0 1.9 1 0 0 1 1 1 1 MATH domain YukD PF08817.10 EGO61125.1 - 0.14 12.9 0.0 3.4 8.4 0.0 2.8 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD BCDHK_Adom3 PF10436.9 EGO61126.1 - 5.7e-42 143.3 2.0 2.7e-41 141.1 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGO61126.1 - 2.3e-05 24.8 0.0 0.00023 21.7 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGO61126.1 - 0.012 15.5 0.0 0.027 14.3 0.0 1.6 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Septin PF00735.18 EGO61127.1 - 9.5e-115 382.7 0.2 1.4e-114 382.1 0.2 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGO61127.1 - 2.1e-07 31.0 0.0 4.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGO61127.1 - 4e-06 26.5 1.6 7.7e-05 22.3 0.1 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGO61127.1 - 4.3e-06 26.7 0.6 3.1e-05 23.9 0.0 2.4 3 0 0 3 3 2 1 RsgA GTPase AAA_22 PF13401.6 EGO61127.1 - 0.0015 18.8 0.6 0.0052 17.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 EGO61127.1 - 0.0026 17.2 0.1 0.0052 16.3 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 EGO61127.1 - 0.0036 17.5 0.1 0.0078 16.4 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EGO61127.1 - 0.0084 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 EGO61127.1 - 0.0091 15.1 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 EGO61127.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Casc1_N PF15927.5 EGO61127.1 - 0.018 14.7 10.0 0.045 13.4 10.0 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Ras PF00071.22 EGO61127.1 - 0.021 14.4 0.7 0.062 12.9 0.5 1.9 2 1 0 2 2 2 0 Ras family AAA_16 PF13191.6 EGO61127.1 - 0.035 14.5 1.1 0.082 13.3 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.14 EGO61127.1 - 0.039 13.2 0.0 0.047 12.9 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain T2SSE PF00437.20 EGO61127.1 - 0.043 12.9 0.4 0.18 10.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 EGO61127.1 - 0.05 13.5 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain FOXP-CC PF16159.5 EGO61127.1 - 0.053 14.2 0.9 0.053 14.2 0.9 2.4 2 1 0 2 2 1 0 FOXP coiled-coil domain ABC_tran PF00005.27 EGO61127.1 - 0.059 13.9 0.1 0.2 12.2 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 EGO61127.1 - 0.081 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EGO61127.1 - 0.15 12.4 0.0 0.43 11.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase PduV-EutP PF10662.9 EGO61127.1 - 0.15 11.8 0.4 8.3 6.2 0.1 2.5 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 EGO61127.1 - 0.28 11.2 6.5 4.2 7.4 0.1 3.2 2 1 1 3 3 3 0 Dynamin family Ribosomal_L6e PF01159.19 EGO61127.1 - 0.9 10.1 5.5 7.8 7.1 0.2 3.2 3 0 0 3 3 3 0 Ribosomal protein L6e AAA_11 PF13086.6 EGO61127.1 - 5.2 6.8 7.6 23 4.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 EGO61128.1 - 2.6e-40 135.6 31.9 1.7e-08 35.0 0.1 13.0 14 0 0 14 14 13 7 WD domain, G-beta repeat Utp12 PF04003.12 EGO61128.1 - 1.8e-24 86.1 0.0 2.7e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EGO61128.1 - 1.9e-23 82.6 0.0 0.0033 17.7 0.0 10.2 6 1 4 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGO61128.1 - 5.3e-09 35.5 0.7 0.78 8.6 0.0 5.9 4 3 3 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGO61128.1 - 8e-08 32.4 1.4 0.059 13.3 0.1 5.6 5 2 2 7 7 7 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGO61128.1 - 0.00074 18.9 0.0 0.58 9.4 0.0 3.9 5 0 0 5 5 5 1 WD40-like domain Nbas_N PF15492.6 EGO61128.1 - 0.0018 17.7 1.5 15 4.8 0.0 4.5 3 2 1 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 EGO61128.1 - 0.018 13.7 2.9 0.23 10.1 0.0 3.4 3 2 0 3 3 3 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EGO61128.1 - 0.028 13.3 0.0 1.3 7.9 0.0 2.9 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Utp13 PF08625.11 EGO61128.1 - 0.065 13.1 0.6 0.25 11.3 0.4 2.1 2 1 0 2 2 2 0 Utp13 specific WD40 associated domain RPN1_RPN2_N PF17781.1 EGO61128.1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain PD40 PF07676.12 EGO61128.1 - 0.21 11.6 4.2 26 4.9 0.0 5.1 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Questin_oxidase PF14027.6 EGO61129.1 - 2.8e-96 323.0 0.5 3.3e-96 322.8 0.5 1.0 1 0 0 1 1 1 1 Questin oxidase-like RNA_replicase_B PF03431.13 EGO61129.1 - 0.078 11.4 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 RNA replicase, beta-chain Exo_endo_phos PF03372.23 EGO61132.1 - 1.6e-10 40.9 0.4 7.6e-10 38.7 0.3 2.3 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.6 EGO61132.1 - 0.022 14.8 0.0 0.061 13.4 0.0 1.7 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 EGO61132.1 - 0.058 13.9 3.3 4.6 7.8 0.0 4.1 3 0 0 3 3 3 0 PQQ-like domain DUF4748 PF15932.5 EGO61133.1 - 6.5e-23 80.2 0.4 1e-22 79.6 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) SARAF PF06682.12 EGO61133.1 - 0.0049 16.6 2.5 0.0053 16.5 2.5 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis CTD_bind PF04818.13 EGO61134.1 - 2.1e-13 50.8 0.2 4.6e-13 49.8 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. SRP-alpha_N PF04086.13 EGO61134.1 - 8.7 6.2 17.2 0.44 10.4 9.3 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal TFIIA PF03153.13 EGO61134.1 - 9.8 6.1 19.6 13 5.6 1.5 2.6 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.16 EGO61135.1 - 1.1e-43 149.6 39.8 8.2e-40 136.8 40.4 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO61135.1 - 1.9e-16 60.0 7.1 1.9e-16 60.0 7.1 3.3 3 0 0 3 3 3 2 Sugar (and other) transporter Wzz PF02706.15 EGO61135.1 - 0.35 11.2 5.1 9.5 6.6 0.0 3.9 3 0 0 3 3 3 0 Chain length determinant protein OppC_N PF12911.7 EGO61135.1 - 2.6 8.1 6.4 1.5 8.9 0.1 3.3 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C PALP PF00291.25 EGO61136.1 - 8.8e-34 117.3 0.0 1.4e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 EGO61136.1 - 1.2e-08 35.4 0.0 8.3e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Gpr1_Fun34_YaaH PF01184.19 EGO61137.1 - 1.4e-11 44.4 0.2 1.5e-11 44.3 0.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Tau95_N PF17682.1 EGO61138.1 - 2.2e-36 124.9 0.1 5.1e-36 123.7 0.1 1.7 1 0 0 1 1 1 1 Tau95 Triple barrel domain Tau95 PF09734.9 EGO61138.1 - 3.7e-36 125.0 0.1 3.7e-36 125.0 0.1 2.0 3 0 0 3 3 3 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain B56 PF01603.20 EGO61139.1 - 2.4e-192 639.5 6.7 2.9e-192 639.2 6.7 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 EGO61139.1 - 0.00051 20.0 2.0 0.31 10.9 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Dynamin_N PF00350.23 EGO61139.1 - 0.09 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Dynamin family AA_permease PF00324.21 EGO61142.1 - 1.1e-58 199.1 32.1 1.3e-58 198.8 32.1 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 EGO61142.1 - 9.6e-25 87.5 0.6 1.2e-08 34.5 0.0 3.2 3 0 0 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 EGO61142.1 - 3.6e-19 68.9 41.7 5.2e-19 68.4 41.7 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 EGO61143.1 - 1.2e-83 281.1 36.4 1.4e-83 280.9 36.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4044 PF13253.6 EGO61143.1 - 0.26 10.8 3.7 0.74 9.4 3.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) RNA_pol_L_2 PF13656.6 EGO61144.1 - 3.2e-24 84.5 0.0 4.1e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGO61144.1 - 9.2e-08 31.4 0.0 1.7e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain cobW PF02492.19 EGO61145.1 - 5.1e-41 140.2 0.0 8.6e-41 139.4 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EGO61145.1 - 0.00047 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 EGO61145.1 - 0.0071 16.1 0.2 0.023 14.5 0.0 1.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EGO61145.1 - 0.013 15.8 0.0 0.063 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain CobW_C PF07683.14 EGO61145.1 - 0.029 14.3 0.0 0.16 11.9 0.0 2.3 2 1 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain AAA_29 PF13555.6 EGO61145.1 - 0.029 14.1 0.1 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGO61145.1 - 0.044 14.2 0.0 0.078 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 EGO61145.1 - 0.073 12.0 0.1 0.16 10.9 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 EGO61145.1 - 0.09 13.3 0.2 0.42 11.2 0.2 2.1 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGO61145.1 - 0.11 12.3 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 NTPase TPK_catalytic PF04263.16 EGO61145.1 - 0.13 12.3 0.3 0.26 11.3 0.3 1.4 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF463 PF04317.12 EGO61145.1 - 0.13 11.1 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 YcjX-like family, DUF463 ARD PF03079.14 EGO61146.1 - 0.033 14.4 1.5 0.045 13.9 1.5 1.2 1 0 0 1 1 1 0 ARD/ARD' family Dak1 PF02733.17 EGO61147.1 - 6.6e-97 324.1 10.1 1.9e-96 322.6 10.1 1.7 1 1 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EGO61147.1 - 4.5e-49 166.7 2.8 4.5e-49 166.7 2.8 1.8 2 0 0 2 2 2 1 DAK2 domain LSM PF01423.22 EGO61148.1 - 5.3e-19 67.7 0.1 7.3e-19 67.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGO61148.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Hfq protein ECH_2 PF16113.5 EGO61149.1 - 6.5e-122 407.2 0.0 9e-122 406.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGO61149.1 - 9.6e-26 90.6 0.0 6e-24 84.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ABC_tran PF00005.27 EGO61150.1 - 1.8e-40 138.6 0.0 3.7e-20 72.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGO61150.1 - 5.5e-32 111.5 9.9 5.7e-18 65.5 0.2 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.6 EGO61150.1 - 4.3e-12 46.5 1.9 0.03 14.1 0.0 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGO61150.1 - 6.4e-12 45.4 4.7 0.0062 16.0 0.1 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGO61150.1 - 2.3e-07 31.2 1.4 0.016 15.5 0.1 3.9 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.6 EGO61150.1 - 7.5e-07 28.9 1.8 0.042 13.4 0.2 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGO61150.1 - 7.9e-07 28.7 2.4 0.0063 16.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGO61150.1 - 7.4e-06 26.4 0.3 0.087 13.2 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 EGO61150.1 - 9.5e-06 25.8 0.1 0.3 11.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EGO61150.1 - 1.2e-05 25.3 0.2 0.0076 16.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EGO61150.1 - 5.9e-05 23.2 7.2 0.00034 20.7 0.4 3.1 3 0 0 3 3 3 1 Dynamin family Pox_A32 PF04665.12 EGO61150.1 - 8.8e-05 22.1 0.9 0.0018 17.8 0.1 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein ATP_bind_1 PF03029.17 EGO61150.1 - 0.00013 21.8 0.1 0.51 10.1 0.0 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 EGO61150.1 - 0.00019 21.2 0.0 0.023 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGO61150.1 - 0.00052 20.6 3.5 0.021 15.3 0.2 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EGO61150.1 - 0.00073 19.2 2.3 0.14 11.7 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EGO61150.1 - 0.0018 18.3 0.3 0.44 10.6 0.0 3.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_19 PF13245.6 EGO61150.1 - 0.0021 18.4 2.0 0.94 9.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EGO61150.1 - 0.0026 17.7 1.6 1.8 8.4 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_7 PF12775.7 EGO61150.1 - 0.0063 16.0 0.1 1.4 8.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region MobB PF03205.14 EGO61150.1 - 0.0081 16.1 0.0 2.1 8.3 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 EGO61150.1 - 0.011 15.5 0.9 6.5 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EGO61150.1 - 0.012 16.1 0.0 7.1 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EGO61150.1 - 0.013 14.9 0.8 0.13 11.6 0.0 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGO61150.1 - 0.014 15.4 0.2 4.8 7.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EGO61150.1 - 0.018 15.5 0.6 15 6.0 0.0 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EGO61150.1 - 0.019 14.1 4.7 0.3 10.1 0.7 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.6 EGO61150.1 - 0.022 14.5 1.1 1.8 8.2 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EGO61150.1 - 0.026 13.9 1.0 3.2 7.0 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 EGO61150.1 - 0.029 14.6 0.1 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SbcCD_C PF13558.6 EGO61150.1 - 0.034 14.4 1.2 0.71 10.1 0.1 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Septin PF00735.18 EGO61150.1 - 0.056 12.7 0.4 10 5.3 0.1 2.3 2 0 0 2 2 2 0 Septin GTP_EFTU PF00009.27 EGO61150.1 - 0.06 12.9 0.7 0.65 9.5 0.0 2.5 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain ABC_ATPase PF09818.9 EGO61150.1 - 0.1 11.4 0.6 2 7.2 0.2 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RNA_helicase PF00910.22 EGO61150.1 - 0.11 13.0 0.3 24 5.4 0.0 3.1 3 0 0 3 3 2 0 RNA helicase AAA_14 PF13173.6 EGO61150.1 - 0.12 12.4 0.1 20 5.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 EGO61150.1 - 0.12 12.1 0.9 4.7 6.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 EGO61150.1 - 0.75 10.0 3.0 16 5.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGO61150.1 - 1.8 8.6 5.3 12 5.9 0.6 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain NTPase_1 PF03266.15 EGO61150.1 - 4 7.3 7.0 25 4.7 0.1 3.3 3 0 0 3 3 3 0 NTPase DUF1754 PF08555.10 EGO61152.1 - 4.8e-20 72.2 17.5 7.5e-20 71.5 17.5 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) Red1 PF07964.11 EGO61152.1 - 0.0077 14.5 13.0 0.0086 14.4 13.0 1.0 1 0 0 1 1 1 1 Rec10 / Red1 DUF5581 PF17744.1 EGO61152.1 - 0.06 12.7 2.2 0.08 12.3 2.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5581) IFT57 PF10498.9 EGO61152.1 - 0.079 11.9 12.3 0.096 11.6 12.3 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 HPIP PF15226.6 EGO61152.1 - 0.14 12.6 0.9 0.27 11.7 0.9 1.5 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family Aminopep PF10023.9 EGO61152.1 - 0.27 10.5 4.4 0.36 10.2 4.4 1.1 1 0 0 1 1 1 0 Putative aminopeptidase FAM60A PF15396.6 EGO61152.1 - 1.4 8.8 9.6 1.8 8.5 9.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PA26 PF04636.13 EGO61152.1 - 2.1 7.2 6.6 2.5 6.9 6.6 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SVIP PF15811.5 EGO61152.1 - 3 8.3 13.7 5.7 7.5 9.2 2.7 2 1 1 3 3 3 0 Small VCP/p97-interacting protein Presenilin PF01080.17 EGO61152.1 - 5.6 5.6 9.3 6.1 5.5 9.3 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EGO61152.1 - 5.8 5.1 17.7 6.8 4.8 17.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1206 PF06724.11 EGO61153.1 - 0.046 13.8 0.9 0.17 12.0 0.9 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) DUF3694 PF12473.8 EGO61154.1 - 0.14 12.8 0.1 0.18 12.5 0.1 1.2 1 0 0 1 1 1 0 Kinesin protein Glyco_hydro_76 PF03663.14 EGO61156.1 - 2.7e-148 494.4 15.3 3.3e-148 494.1 15.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 NAP PF00956.18 EGO61157.1 - 1.4e-24 86.7 13.8 6e-23 81.4 7.3 2.9 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) BUD22 PF09073.10 EGO61157.1 - 0.004 16.6 23.4 0.005 16.2 23.4 1.2 1 0 0 1 1 1 1 BUD22 MscS_TM PF12794.7 EGO61157.1 - 0.026 13.4 6.9 0.041 12.7 6.9 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DDHD PF02862.17 EGO61157.1 - 0.041 14.1 0.3 0.06 13.5 0.3 1.4 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.13 EGO61157.1 - 0.055 13.5 16.5 0.084 12.9 16.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Voldacs PF03517.13 EGO61157.1 - 0.18 11.9 18.1 0.38 10.9 18.1 1.5 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling AIM3 PF17096.5 EGO61157.1 - 0.22 12.5 0.2 0.22 12.5 0.2 2.4 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 Adeno_terminal PF02459.15 EGO61157.1 - 0.39 9.1 5.7 0.74 8.1 5.7 1.4 1 0 0 1 1 1 0 Adenoviral DNA terminal protein SAPS PF04499.15 EGO61157.1 - 0.53 9.0 7.8 0.67 8.7 7.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NOA36 PF06524.12 EGO61157.1 - 0.55 9.5 27.5 0.37 10.1 8.5 2.2 2 0 0 2 2 2 0 NOA36 protein BSP_II PF05432.11 EGO61157.1 - 0.7 9.5 24.0 0.14 11.9 15.6 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) BT1 PF03092.16 EGO61157.1 - 0.76 7.9 2.7 1.1 7.5 2.7 1.2 1 0 0 1 1 1 0 BT1 family Myc_N PF01056.18 EGO61157.1 - 0.89 9.4 18.0 0.25 11.2 8.1 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Presenilin PF01080.17 EGO61157.1 - 0.95 8.2 5.5 1.2 7.8 5.5 1.3 1 0 0 1 1 1 0 Presenilin PBP_sp32 PF07222.12 EGO61157.1 - 1.1 8.7 11.3 2 7.8 11.3 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CENP-B_dimeris PF09026.10 EGO61157.1 - 1.8 9.0 35.0 2.1 8.8 12.4 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 EGO61157.1 - 3.3 7.7 21.6 1.3 9.0 6.9 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal AAA_23 PF13476.6 EGO61157.1 - 4 7.9 18.2 0.46 10.9 10.4 2.3 1 1 0 2 2 2 0 AAA domain DUF1840 PF08895.11 EGO61157.1 - 6.2 7.2 18.5 1.7 9.0 9.1 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF1840) V_ATPase_I PF01496.19 EGO61157.1 - 6.9 4.4 5.1 13 3.5 5.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MRNIP PF15749.5 EGO61157.1 - 9.5 7.0 11.3 2.3 9.0 5.0 2.4 2 0 0 2 2 2 0 MRN-interacting protein Asparaginase PF00710.20 EGO61158.1 - 7.6e-58 195.2 0.0 1.4e-57 194.4 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EGO61158.1 - 4.3e-25 88.1 0.0 7.5e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 EGO61158.1 - 8.7e-15 55.1 0.0 1.3e-08 35.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGO61158.1 - 1.9e-07 31.2 0.1 0.0016 18.8 0.1 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EGO61158.1 - 7.2e-06 26.5 0.0 0.014 15.9 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGO61158.1 - 6e-05 23.1 0.1 0.17 12.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGO61158.1 - 0.073 13.4 0.3 2.6 8.5 0.2 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) BCS1_N PF08740.11 EGO61159.1 - 3.5e-52 177.1 2.5 3.5e-52 177.1 2.5 3.0 2 2 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 EGO61159.1 - 1.4e-15 57.9 0.3 9.5e-07 29.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGO61159.1 - 0.0076 16.2 0.0 0.023 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGO61159.1 - 0.028 14.6 0.6 0.11 12.6 0.0 2.3 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 EGO61159.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain UPF0270 PF06794.12 EGO61159.1 - 0.055 13.5 0.1 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) AAA_18 PF13238.6 EGO61159.1 - 0.059 13.9 1.1 0.63 10.6 0.0 3.2 3 1 1 4 4 4 0 AAA domain ATPase PF06745.13 EGO61159.1 - 0.095 12.0 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 EGO61159.1 - 0.11 12.8 0.4 0.43 10.9 0.4 2.0 1 1 0 1 1 1 0 AAA ATPase domain CDC45 PF02724.14 EGO61159.1 - 1.4 7.1 15.9 2.8 6.1 15.9 1.4 1 0 0 1 1 1 0 CDC45-like protein LSM PF01423.22 EGO61160.1 - 6.8e-23 80.2 0.2 7.5e-23 80.0 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGO61160.1 - 0.0055 16.8 0.0 0.0066 16.6 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain DNA_pol_A_exo1 PF01612.20 EGO61161.1 - 2.5e-11 43.6 0.0 5e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Herpes_IE1 PF07340.11 EGO61161.1 - 0.018 14.0 0.2 0.027 13.4 0.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein WD40 PF00400.32 EGO61162.1 - 2e-21 75.9 14.4 3.4e-07 30.8 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat NLE PF08154.12 EGO61162.1 - 4.7e-17 62.3 0.1 8.4e-17 61.5 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EGO61162.1 - 2.9e-05 22.9 2.7 0.0014 17.4 0.4 3.0 1 1 2 4 4 4 2 Nucleoporin Nup120/160 DNA_pol_E_B PF04042.16 EGO61163.1 - 2e-55 187.4 0.0 2.7e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EGO61163.1 - 8e-42 142.4 0.0 1.3e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain CAP_N PF01213.19 EGO61164.1 - 0.026 14.0 3.2 0.075 12.5 3.2 1.8 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 EGO61164.1 - 0.51 10.4 5.2 1.1 9.3 5.2 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CDC45 PF02724.14 EGO61164.1 - 1.7 6.9 8.5 3.2 5.9 8.5 1.4 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 EGO61164.1 - 3.8 8.0 17.1 0.74 10.2 10.6 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PALP PF00291.25 EGO61165.1 - 2.1e-61 207.9 0.6 2.5e-61 207.7 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Acetyltransf_3 PF13302.7 EGO61166.1 - 1.5e-30 106.6 0.0 1.9e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO61166.1 - 1e-06 28.6 0.0 0.016 15.1 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_8 PF13523.6 EGO61166.1 - 1.2e-05 25.1 0.1 3.2 7.4 0.0 3.1 3 0 0 3 3 3 3 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGO61166.1 - 0.0026 17.9 0.2 0.0078 16.4 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGO61166.1 - 0.0058 17.0 0.0 0.018 15.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO61166.1 - 0.01 16.1 0.1 0.66 10.2 0.1 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family tRNA-synt_1g PF09334.11 EGO61167.1 - 9.3e-97 324.2 3.0 1.2e-95 320.6 3.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGO61167.1 - 1.5e-24 86.3 8.3 1.3e-09 36.9 0.6 4.1 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EGO61167.1 - 1.4e-09 37.8 0.1 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain DUF5331 PF17265.2 EGO61167.1 - 0.058 13.1 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5331) DUF3039 PF11238.8 EGO61168.1 - 0.065 13.0 0.2 18 5.2 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) Trm112p PF03966.16 EGO61168.1 - 0.11 13.1 0.1 3.3 8.4 0.0 2.8 2 0 0 2 2 2 0 Trm112p-like protein Ribosomal_L4 PF00573.22 EGO61170.1 - 3.1e-38 131.4 0.7 4.5e-38 130.9 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EGO61170.1 - 3.5e-30 103.9 0.8 3.5e-30 103.9 0.8 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Aminotran_1_2 PF00155.21 EGO61171.1 - 3e-10 39.8 0.0 3.6e-08 33.0 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class I and II Tannase PF07519.11 EGO61171.1 - 0.19 10.6 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase FMO-like PF00743.19 EGO61172.1 - 1.2e-43 149.3 0.0 3.6e-25 88.4 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 EGO61172.1 - 4.6e-15 55.9 0.0 3.9e-14 52.9 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EGO61172.1 - 5.8e-14 52.1 0.2 8e-07 28.6 0.2 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGO61172.1 - 2e-12 46.9 0.0 3.9e-12 46.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGO61172.1 - 5.6e-12 45.4 0.3 2.1e-08 33.7 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGO61172.1 - 2e-08 34.3 0.0 4.9e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO61172.1 - 1.3e-07 31.5 0.0 0.0002 21.1 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 EGO61172.1 - 8.1e-07 28.5 0.1 8e-05 22.0 0.0 2.6 3 0 0 3 3 3 1 Thi4 family MCRA PF06100.11 EGO61172.1 - 0.00064 18.6 0.1 0.0044 15.9 0.0 1.9 2 0 0 2 2 2 1 MCRA family Amino_oxidase PF01593.24 EGO61172.1 - 0.00072 19.0 0.0 0.06 12.6 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EGO61172.1 - 0.0015 19.1 0.1 0.3 11.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EGO61172.1 - 0.0047 17.0 0.0 0.017 15.2 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 EGO61172.1 - 0.01 14.6 0.5 0.069 11.8 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 EGO61172.1 - 0.14 11.2 0.0 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 EGO61172.1 - 0.15 11.3 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EGO61172.1 - 0.18 10.8 0.0 2.2 7.2 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein POT1 PF02765.17 EGO61173.1 - 5.4e-09 36.0 0.0 1.8e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Grg1 PF11034.8 EGO61174.1 - 1.5e-33 114.8 13.5 1.6e-33 114.7 13.5 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 Transposon_TraM PF12508.8 EGO61174.1 - 0.038 13.7 2.0 0.041 13.6 2.0 1.0 1 0 0 1 1 1 0 Conjugative transposon, TraM EBP PF05241.12 EGO61176.1 - 1.3e-69 233.2 8.3 1.6e-69 233.0 8.3 1.0 1 0 0 1 1 1 1 Emopamil binding protein TMEM208_SND2 PF05620.11 EGO61176.1 - 0.072 12.9 5.2 0.43 10.3 0.8 2.5 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 HAGH_C PF16123.5 EGO61179.1 - 4.3e-22 78.4 0.3 6.6e-22 77.8 0.3 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EGO61179.1 - 2e-17 63.9 3.9 1.7e-15 57.6 3.9 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGO61179.1 - 0.0024 17.4 0.9 0.041 13.4 0.9 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Peripla_BP_4 PF13407.6 EGO61179.1 - 0.078 12.5 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 Periplasmic binding protein domain Las1 PF04031.13 EGO61180.1 - 1.2e-63 213.8 0.2 1.5e-63 213.5 0.2 1.1 1 0 0 1 1 1 1 Las1-like Sacchrp_dh_C PF16653.5 EGO61181.1 - 5e-96 321.9 0.0 1.2e-95 320.6 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EGO61181.1 - 8.6e-26 90.7 0.3 1.4e-25 90.0 0.3 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EGO61181.1 - 2.6e-05 24.3 0.1 5.5e-05 23.3 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EGO61181.1 - 9.4e-05 22.4 0.4 0.00022 21.1 0.5 1.7 1 1 0 1 1 1 1 NAD(P)H-binding IlvN PF07991.12 EGO61181.1 - 0.0022 17.6 0.2 0.12 11.9 0.1 2.9 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GFO_IDH_MocA PF01408.22 EGO61181.1 - 0.019 15.8 0.4 0.072 13.9 0.1 2.1 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EGO61181.1 - 0.11 13.1 0.2 0.2 12.3 0.2 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain UBA PF00627.31 EGO61181.1 - 0.12 12.3 0.0 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 UBA/TS-N domain S-antigen PF05756.11 EGO61182.1 - 0.57 10.6 2.6 1.1 9.7 2.6 1.4 1 0 0 1 1 1 0 S-antigen protein PfkB PF00294.24 EGO61185.1 - 0.039 13.3 0.0 0.22 10.8 0.0 1.9 2 0 0 2 2 2 0 pfkB family carbohydrate kinase Pex14_N PF04695.13 EGO61185.1 - 0.049 14.3 4.1 0.071 13.8 4.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NAD_kinase PF01513.21 EGO61186.1 - 3.1e-71 240.0 0.0 1e-70 238.2 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EGO61186.1 - 0.082 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain zf-rbx1 PF12678.7 EGO61187.1 - 3.8e-09 36.7 1.7 9.5e-09 35.4 1.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGO61187.1 - 6.7e-08 32.8 2.2 6.7e-08 32.8 2.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGO61187.1 - 1.5e-06 27.9 0.7 2.7e-06 27.1 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO61187.1 - 3e-06 27.0 4.9 8.6e-06 25.5 1.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO61187.1 - 6.1e-06 26.1 3.6 2.1e-05 24.4 3.7 1.8 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGO61187.1 - 7.4e-06 25.7 0.4 1.8e-05 24.5 0.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGO61187.1 - 3.6e-05 23.7 3.4 0.00012 22.0 0.5 2.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGO61187.1 - 0.0011 18.7 1.6 0.0011 18.7 1.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2921 PF11145.8 EGO61187.1 - 0.0031 15.4 0.8 0.0075 14.2 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2921) Zn_ribbon_17 PF17120.5 EGO61187.1 - 0.006 16.2 0.8 0.014 15.0 0.8 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EGO61187.1 - 0.0063 16.2 0.6 0.0063 16.2 0.6 3.3 3 0 0 3 3 3 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EGO61187.1 - 0.0071 16.4 0.9 0.017 15.2 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PQ-loop PF04193.14 EGO61187.1 - 0.0089 15.8 0.9 0.031 14.0 0.9 1.9 1 0 0 1 1 1 1 PQ loop repeat Tetraspanin PF00335.20 EGO61187.1 - 0.032 14.0 0.2 0.054 13.2 0.2 1.3 1 0 0 1 1 1 0 Tetraspanin family Pex14_N PF04695.13 EGO61187.1 - 0.24 12.0 6.0 0.98 10.1 6.0 2.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C3H2C3 PF17122.5 EGO61187.1 - 1.1 9.3 4.7 1.5 9.0 1.4 2.3 2 0 0 2 2 2 0 Zinc-finger Rrn6 PF10214.9 EGO61187.1 - 3.4 6.0 6.3 6 5.2 6.3 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor zf-C3HC4_4 PF15227.6 EGO61187.1 - 5.4 7.3 5.1 27 5.0 1.4 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING HSBP1 PF06825.12 EGO61188.1 - 4.1e-16 58.6 0.7 5.1e-16 58.3 0.7 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Apolipoprotein PF01442.18 EGO61188.1 - 0.0018 18.1 0.3 0.002 18.1 0.3 1.0 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain CLZ PF16526.5 EGO61188.1 - 0.0023 18.3 0.2 0.0026 18.1 0.2 1.1 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Matrilin_ccoil PF10393.9 EGO61188.1 - 0.021 14.7 0.4 0.089 12.7 0.4 2.0 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Peptidase_C50 PF03568.17 EGO61188.1 - 0.022 13.9 0.0 0.023 13.8 0.0 1.0 1 0 0 1 1 1 0 Peptidase family C50 Baculo_PEP_C PF04513.12 EGO61188.1 - 0.024 14.7 0.6 0.027 14.5 0.6 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med30 PF11315.8 EGO61188.1 - 0.043 14.0 0.0 0.051 13.8 0.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 30 DUF1664 PF07889.12 EGO61188.1 - 0.056 13.5 0.1 0.068 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Thioredoxin PF00085.20 EGO61189.1 - 6.4e-60 199.6 0.0 3.9e-30 103.9 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EGO61189.1 - 1.7e-26 92.9 2.2 2.6e-26 92.4 0.8 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 EGO61189.1 - 4.3e-19 69.0 0.0 3.8e-09 37.0 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EGO61189.1 - 1.2e-13 51.0 0.0 3e-06 26.8 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGO61189.1 - 2.9e-09 37.0 0.0 0.002 18.3 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EGO61189.1 - 5.1e-09 36.3 0.0 0.00046 20.5 0.0 3.4 2 2 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EGO61189.1 - 5e-07 29.7 0.1 0.014 15.3 0.0 2.4 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.6 EGO61189.1 - 4.9e-06 26.6 0.0 0.013 15.4 0.0 2.8 2 1 1 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.10 EGO61189.1 - 2.9e-05 23.8 0.5 0.069 12.9 0.0 2.3 1 1 1 2 2 2 2 Redoxin ERp29_N PF07912.13 EGO61189.1 - 3.1e-05 24.1 0.1 0.00039 20.6 0.0 2.6 3 0 0 3 3 3 1 ERp29, N-terminal domain TraF PF13728.6 EGO61189.1 - 0.00019 21.3 0.0 0.16 11.8 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 EGO61189.1 - 0.00041 20.1 0.0 0.4 10.5 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 EGO61189.1 - 0.0006 20.0 0.4 2.6 8.3 0.1 3.2 2 2 0 2 2 2 2 Glutaredoxin HyaE PF07449.11 EGO61189.1 - 0.00091 19.2 0.1 0.033 14.1 0.0 2.8 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 EGO61189.1 - 0.0012 18.8 0.0 0.53 10.4 0.0 3.1 3 0 0 3 3 2 1 Thioredoxin domain Thioredoxin_4 PF13462.6 EGO61189.1 - 0.003 17.7 0.3 4.8 7.3 0.0 3.2 2 2 1 3 3 3 2 Thioredoxin Thioredoxin_5 PF13743.6 EGO61189.1 - 0.012 15.3 0.2 24 4.6 0.0 3.7 2 2 2 4 4 4 0 Thioredoxin DSBA PF01323.20 EGO61189.1 - 0.046 13.5 1.6 29 4.4 0.0 4.0 3 2 2 5 5 5 0 DSBA-like thioredoxin domain DUF1910 PF08928.10 EGO61189.1 - 0.066 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) DUF836 PF05768.14 EGO61189.1 - 0.12 12.8 0.0 2.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Ribosomal_S14 PF00253.21 EGO61190.1 - 7.4e-16 57.7 3.3 8e-16 57.5 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e GTP_EFTU PF00009.27 EGO61191.1 - 8e-57 191.9 0.1 1.1e-56 191.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGO61191.1 - 7e-24 84.3 0.0 1.7e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGO61191.1 - 2.8e-16 59.6 5.0 3.4e-16 59.4 3.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGO61191.1 - 1.9e-05 24.7 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGO61191.1 - 0.024 14.6 0.0 0.065 13.1 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 EGO61191.1 - 0.041 13.5 0.1 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EGO61191.1 - 0.13 12.0 0.3 20 4.9 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MARVEL PF01284.23 EGO61193.1 - 0.043 13.9 9.2 0.14 12.2 9.2 1.9 1 1 0 1 1 1 0 Membrane-associating domain Ribosomal_L37ae PF01780.19 EGO61194.1 - 2e-07 31.0 0.1 2.5e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal L37ae protein family DUF5351 PF17302.2 EGO61194.1 - 0.068 13.4 0.7 0.11 12.7 0.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5351) DnaJ_C PF01556.18 EGO61196.1 - 1.5e-41 141.9 0.9 2e-41 141.5 0.9 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGO61196.1 - 2.9e-29 101.0 1.7 4.7e-29 100.3 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain HAD_2 PF13419.6 EGO61198.1 - 4.6e-23 82.2 0.0 5.9e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGO61198.1 - 9.5e-15 55.5 0.1 3.4e-14 53.6 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 EGO61198.1 - 4.4e-07 29.8 0.0 1.1e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_like PF13242.6 EGO61198.1 - 7.6e-06 25.9 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EGO61198.1 - 0.0023 18.4 0.0 0.0034 17.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EGO61198.1 - 0.029 14.5 0.0 2.1 8.5 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pre-PUA PF17832.1 EGO61198.1 - 0.13 12.9 0.1 0.41 11.4 0.0 1.8 2 0 0 2 2 2 0 Pre-PUA-like domain Rit1_C PF17184.4 EGO61199.1 - 3e-109 364.7 0.0 4.1e-109 364.2 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EGO61199.1 - 9.1e-35 119.3 0.0 2e-34 118.2 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain Fungal_trans_2 PF11951.8 EGO61201.1 - 0.00016 20.6 0.0 0.00051 19.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pex14_N PF04695.13 EGO61201.1 - 1.6 9.4 9.5 0.7 10.5 0.6 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3402 PF11882.8 EGO61202.1 - 2.5e-201 669.8 0.0 5.5e-201 668.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.13 EGO61202.1 - 2e-100 335.7 0.0 2.9e-100 335.2 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein DUF2011 PF09428.10 EGO61203.1 - 5.2e-25 87.5 0.0 1.8e-24 85.8 0.0 2.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) CCDC53 PF10152.9 EGO61203.1 - 0.022 15.2 7.3 0.022 15.2 7.3 2.6 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex zf-HC2 PF13490.6 EGO61203.1 - 0.032 14.5 2.2 0.034 14.4 0.0 2.2 2 0 0 2 2 2 0 Putative zinc-finger RR_TM4-6 PF06459.12 EGO61203.1 - 0.48 10.2 27.3 0.83 9.4 12.7 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 EGO61203.1 - 9.1 6.2 19.3 2.9 7.8 0.9 2.4 2 0 0 2 2 2 0 Protein Family FAM60A NDT80_PhoG PF05224.12 EGO61204.1 - 5.3e-40 137.6 0.0 1.4e-39 136.3 0.0 1.7 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family IBR PF01485.21 EGO61208.1 - 2.2e-21 75.9 37.2 7.3e-16 58.1 6.0 4.0 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 EGO61208.1 - 4.2e-19 68.9 0.0 1e-18 67.7 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 EGO61208.1 - 0.00018 21.8 7.5 0.00018 21.8 7.5 3.9 3 1 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 EGO61208.1 - 0.0013 18.7 5.0 0.0013 18.7 5.0 3.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGO61208.1 - 0.0025 17.6 8.1 0.0025 17.6 8.1 4.1 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGO61208.1 - 0.013 15.4 6.7 0.013 15.4 6.7 4.1 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGO61208.1 - 0.028 14.2 8.7 0.091 12.5 8.7 2.0 1 0 0 1 1 1 0 RING-like zinc finger MRC1 PF09444.10 EGO61208.1 - 0.16 12.4 3.2 0.57 10.7 0.1 2.5 2 0 0 2 2 2 0 MRC1-like domain PAP2 PF01569.21 EGO61209.1 - 1.3e-11 44.4 2.8 1.3e-11 44.4 2.8 2.1 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 EGO61209.1 - 0.031 14.4 0.1 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 Divergent PAP2 family CSRNP_N PF16019.5 EGO61209.1 - 0.038 13.9 0.1 0.056 13.4 0.1 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus UbiA PF01040.18 EGO61209.1 - 0.11 11.8 8.7 0.073 12.4 3.5 2.3 1 1 1 2 2 2 0 UbiA prenyltransferase family Lig_chan PF00060.26 EGO61209.1 - 0.12 12.3 0.2 0.39 10.5 0.2 2.0 1 1 0 1 1 1 0 Ligand-gated ion channel IF4E PF01652.18 EGO61210.1 - 1.6e-38 132.0 0.3 2.1e-38 131.6 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4598 PF15370.6 EGO61211.1 - 2.1e-09 37.8 11.1 1.7e-08 34.9 11.1 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4598) Kinesin PF00225.23 EGO61212.1 - 5.9e-114 380.5 0.0 7.7e-114 380.1 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGO61212.1 - 9.8e-26 90.5 0.0 1.8e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding YabA PF06156.13 EGO61212.1 - 0.32 11.6 6.0 7.6 7.2 0.1 3.1 2 1 0 2 2 2 0 Initiation control protein YabA Cytochrom_B562 PF07361.11 EGO61212.1 - 0.6 10.8 5.4 0.33 11.6 2.8 1.9 2 0 0 2 2 2 0 Cytochrome b562 PUL PF08324.11 EGO61213.1 - 1.9e-62 211.0 0.1 2.6e-62 210.6 0.1 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 EGO61213.1 - 3.6e-15 56.1 0.0 2.6e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 PPPDE putative peptidase domain Thioredoxin PF00085.20 EGO61213.1 - 6.3e-13 48.6 0.0 1.2e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 EGO61213.1 - 0.008 16.0 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 EGO61213.1 - 0.012 15.5 0.1 0.044 13.7 0.1 1.9 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_2 PF13098.6 EGO61213.1 - 0.014 15.9 0.5 0.18 12.3 0.5 2.3 1 1 0 1 1 1 0 Thioredoxin-like domain Redoxin PF08534.10 EGO61213.1 - 0.04 13.6 0.1 0.082 12.6 0.1 1.4 1 0 0 1 1 1 0 Redoxin GDA1_CD39 PF01150.17 EGO61215.1 - 2.6e-98 329.5 0.0 3.5e-98 329.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family AAA_lid_2 PF17863.1 EGO61216.1 - 1.6e-05 24.7 0.1 2.2e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 AAA lid domain Ras PF00071.22 EGO61217.1 - 3.2e-57 192.6 0.1 3.8e-57 192.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO61217.1 - 3.3e-32 111.2 0.0 4.7e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO61217.1 - 8.4e-14 51.4 0.0 9.9e-14 51.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGO61217.1 - 4.9e-08 33.0 0.0 8.2e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGO61217.1 - 2e-06 27.3 0.0 2.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGO61217.1 - 6e-06 25.9 0.1 0.00018 21.1 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGO61217.1 - 0.00012 22.0 0.2 0.0037 17.2 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase SRPRB PF09439.10 EGO61217.1 - 0.0023 17.4 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGO61217.1 - 0.0028 17.4 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EGO61217.1 - 0.0038 17.2 0.0 0.0068 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 EGO61217.1 - 0.005 16.6 0.3 0.14 11.9 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EGO61217.1 - 0.0089 16.4 0.0 0.014 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGO61217.1 - 0.0096 16.2 0.0 0.016 15.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGO61217.1 - 0.02 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EGO61217.1 - 0.02 14.2 0.3 0.048 12.9 0.0 1.7 2 1 1 3 3 3 0 Septin NB-ARC PF00931.22 EGO61217.1 - 0.022 14.0 0.1 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 EGO61217.1 - 0.024 14.1 0.1 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 EGO61217.1 - 0.043 13.4 0.0 0.1 12.2 0.0 1.6 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EGO61217.1 - 0.062 13.2 0.2 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EGO61217.1 - 0.098 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 EGO61217.1 - 0.12 12.8 0.0 0.51 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase TniB PF05621.11 EGO61217.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 EGO61217.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF3955 PF13127.6 EGO61218.1 - 8.9e-09 35.0 2.2 8.9e-09 35.0 2.2 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) PUNUT PF16913.5 EGO61218.1 - 3.9e-06 26.3 4.2 3.9e-06 26.3 4.2 2.1 2 1 1 3 3 3 1 Purine nucleobase transmembrane transport EamA PF00892.20 EGO61218.1 - 4.3e-06 27.0 37.6 1.8e-05 25.0 5.6 4.1 3 1 1 4 4 4 3 EamA-like transporter family SLC35F PF06027.12 EGO61218.1 - 0.00023 20.8 1.2 0.00023 20.8 1.2 2.2 2 1 1 3 3 3 1 Solute carrier family 35 7tm_7 PF08395.12 EGO61218.1 - 0.014 14.6 0.9 0.014 14.6 0.9 2.2 2 0 0 2 2 2 0 7tm Chemosensory receptor DUF3953 PF13129.6 EGO61218.1 - 0.92 9.3 7.6 4.3 7.2 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) Heme_oxygenase PF01126.20 EGO61219.1 - 2.4e-09 37.3 0.0 6.1e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Heme oxygenase MobB PF03205.14 EGO61219.1 - 0.043 13.7 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B YlqD PF11068.8 EGO61219.1 - 2.5 8.5 6.3 18 5.7 0.8 2.6 2 0 0 2 2 2 0 YlqD protein Methyltransf_16 PF10294.9 EGO61220.1 - 2.9e-11 43.4 0.0 4.4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EGO61220.1 - 0.00039 19.9 0.0 0.00055 19.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGO61220.1 - 0.018 15.8 0.0 0.038 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MIG-14_Wnt-bd PF06664.12 EGO61221.1 - 0.028 13.7 0.0 0.031 13.5 0.0 1.0 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion zf-FPG_IleRS PF06827.14 EGO61222.1 - 0.15 12.0 1.6 2.9 7.8 0.1 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS NPH-II PF12011.8 EGO61222.1 - 0.16 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 RNA helicase NPH-II DUF1660 PF07874.11 EGO61222.1 - 0.23 12.0 2.1 4.6 7.8 0.0 2.3 1 1 1 2 2 2 0 Prophage protein (DUF1660) Peptidase_C12 PF01088.21 EGO61224.1 - 4e-68 229.3 0.0 5.2e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EGO61224.1 - 1.1e-10 41.2 0.1 2.8e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Fibrillarin PF01269.17 EGO61225.1 - 5.4e-104 346.2 0.0 6.7e-104 345.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EGO61225.1 - 3.7e-06 26.8 0.0 5.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EGO61225.1 - 0.005 16.6 0.1 0.0074 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 EGO61225.1 - 0.026 14.2 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F zf-C2H2 PF00096.26 EGO61230.1 - 4.8e-05 23.6 18.0 0.53 10.8 1.2 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO61230.1 - 0.044 14.6 20.6 0.44 11.5 1.0 4.7 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2HE PF16278.5 EGO61230.1 - 0.059 13.8 0.8 3.2 8.3 0.1 2.7 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger TOC159_MAD PF11886.8 EGO61230.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain zf-TAZ PF02135.16 EGO61230.1 - 0.18 12.3 4.2 0.26 11.8 1.6 2.1 2 0 0 2 2 2 0 TAZ zinc finger FOXP-CC PF16159.5 EGO61230.1 - 7.3 7.3 6.2 41 4.9 1.2 3.1 3 0 0 3 3 3 0 FOXP coiled-coil domain FAD_binding_1 PF00667.20 EGO61233.1 - 3.9e-45 154.1 0.0 5.6e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EGO61233.1 - 2.8e-10 40.8 0.0 1.1e-09 38.9 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Nitroreductase PF00881.24 EGO61234.1 - 5.9e-18 65.5 0.0 7.1e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family Sun2_CC2 PF18580.1 EGO61234.1 - 0.09 13.0 1.2 2.4 8.4 0.0 2.9 3 0 0 3 3 3 0 SUN2 coiled coil domain 2 PS_Dcarbxylase PF02666.15 EGO61235.1 - 1.1e-77 260.2 0.0 5.7e-76 254.5 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 EGO61235.1 - 0.048 13.4 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 MNLL subunit ubiquitin PF00240.23 EGO61237.1 - 0.00017 21.3 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EGO61237.1 - 0.00033 21.2 0.2 0.00094 19.7 0.2 1.9 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Sdh_cyt PF01127.22 EGO61237.1 - 0.073 13.1 3.7 0.14 12.2 3.7 1.4 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit adh_short_C2 PF13561.6 EGO61238.1 - 9.9e-50 169.3 1.0 1.2e-49 169.0 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGO61238.1 - 2.5e-44 151.1 0.4 4.5e-44 150.2 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EGO61238.1 - 8.2e-12 45.4 0.5 1.3e-11 44.7 0.5 1.2 1 0 0 1 1 1 1 KR domain malic PF00390.19 EGO61238.1 - 0.19 11.5 0.1 3.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain N2227 PF07942.12 EGO61239.1 - 8.1e-109 363.0 0.0 9.9e-109 362.7 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 EGO61239.1 - 8.3e-05 22.5 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO61239.1 - 0.0017 19.0 0.0 0.0052 17.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO61239.1 - 0.0057 17.4 0.0 0.045 14.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain PAC4 PF16093.5 EGO61240.1 - 1e-21 76.9 0.1 1.4e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 HEAT_EZ PF13513.6 EGO61241.1 - 2.4e-32 111.0 14.0 3.8e-16 59.2 0.0 10.7 10 2 2 12 12 11 4 HEAT-like repeat HEAT PF02985.22 EGO61241.1 - 8e-22 75.5 21.7 6.2e-06 26.0 0.0 12.0 13 0 0 13 13 12 4 HEAT repeat HEAT_2 PF13646.6 EGO61241.1 - 2e-20 73.0 1.5 1.8e-06 28.2 0.0 7.4 4 2 2 6 6 6 3 HEAT repeats Cnd1 PF12717.7 EGO61241.1 - 9.7e-12 45.2 0.0 0.2 11.7 0.0 5.9 4 2 0 6 6 6 3 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EGO61241.1 - 3.1e-10 39.8 1.5 0.018 14.2 0.0 4.9 4 1 1 5 5 5 3 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 EGO61241.1 - 2.2e-08 34.6 0.2 0.016 15.7 0.0 5.2 5 1 0 5 5 4 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 EGO61241.1 - 8.5e-07 28.8 1.3 6.2e-05 22.8 0.5 4.4 4 1 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.23 EGO61241.1 - 9.1e-06 25.5 4.2 0.3 11.2 0.0 5.3 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat DRIM PF07539.12 EGO61241.1 - 0.0095 14.3 0.1 0.69 8.1 0.1 3.4 3 1 0 3 3 3 1 Down-regulated in metastasis DUF3437 PF11919.8 EGO61241.1 - 0.011 15.6 0.1 4.5 7.3 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) HEAT_PBS PF03130.16 EGO61241.1 - 0.019 15.6 1.0 16 6.6 0.0 5.2 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat RIX1 PF08167.12 EGO61241.1 - 0.03 14.1 0.1 24 4.6 0.0 4.5 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 EGO61241.1 - 0.038 14.2 0.4 0.75 10.0 0.0 3.2 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 TAF6_C PF07571.13 EGO61241.1 - 0.094 13.0 0.0 12 6.3 0.0 4.0 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain Zn_clus PF00172.18 EGO61244.1 - 1.2e-07 31.7 11.1 1.9e-07 31.1 11.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGO61244.1 - 1.9e-07 30.2 0.2 3.5e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Exo_endo_phos PF03372.23 EGO61247.1 - 0.0001 21.9 0.2 0.00023 20.8 0.2 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EGO61247.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.5 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase IL32 PF15225.6 EGO61248.1 - 5.7 7.4 4.6 1.1 9.7 0.1 2.1 3 0 0 3 3 3 0 Interleukin 32 SPRY PF00622.28 EGO61250.1 - 3.1e-19 69.3 0.1 5e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 SPRY domain YqgB PF11036.8 EGO61250.1 - 0.13 12.0 0.3 0.32 10.7 0.3 1.6 1 0 0 1 1 1 0 Virulence promoting factor Haem_degrading PF03928.14 EGO61251.1 - 0.065 13.3 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 Haem-degrading SAP PF02037.27 EGO61252.1 - 2.5e-15 55.8 0.0 4.2e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 EGO61252.1 - 0.0015 18.3 4.3 0.0018 18.0 0.6 2.6 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain HeH PF12949.7 EGO61252.1 - 0.067 12.9 1.5 0.48 10.2 0.1 2.5 2 1 0 2 2 2 0 HeH/LEM domain Sterol-sensing PF12349.8 EGO61253.1 - 1.9e-43 147.9 8.8 3.5e-43 147.1 8.8 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EGO61253.1 - 4.1e-12 45.0 4.4 6.4e-12 44.4 4.4 1.3 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 EGO61253.1 - 0.016 16.0 0.8 0.13 13.2 0.2 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat Cupin_8 PF13621.6 EGO61257.1 - 1.2e-57 195.6 0.0 1.6e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGO61257.1 - 7.9e-06 25.6 0.0 0.003 17.1 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein Spb1_C PF07780.12 EGO61258.1 - 5.6e-89 297.3 22.5 5.6e-89 297.3 22.5 4.0 3 2 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 EGO61258.1 - 1.8e-56 191.0 0.0 3.2e-56 190.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EGO61258.1 - 3.8e-52 176.4 11.5 3.8e-52 176.4 11.5 5.1 3 1 2 5 5 5 1 Domain of unknown function (DUF3381) E1_FCCH PF16190.5 EGO61258.1 - 0.052 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain Methyltransf_23 PF13489.6 EGO61258.1 - 0.095 12.5 0.0 0.29 11.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 EGO61259.1 - 3.6e-13 49.8 2.2 0.16 12.9 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO61259.1 - 3.1e-05 24.2 0.0 0.14 12.5 0.0 5.2 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO61259.1 - 0.17 10.5 0.0 5.2 5.6 0.0 2.7 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Tim54 PF11711.8 EGO61261.1 - 0.37 9.5 8.0 0.94 8.2 8.0 1.7 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MKT1_C PF12246.8 EGO61264.1 - 1.2e-07 31.3 0.0 1.2e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication RabGAP-TBC PF00566.18 EGO61265.1 - 2e-36 125.7 0.4 4e-36 124.7 0.4 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 EGO61265.1 - 0.00048 19.6 0.0 0.03 13.8 0.0 2.9 2 1 0 2 2 2 1 Rab-binding domain (RBD) Frag1 PF10277.9 EGO61266.1 - 1.1e-46 159.1 17.5 1.3e-46 158.9 17.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family EMP70 PF02990.16 EGO61266.1 - 0.079 11.6 5.2 0.11 11.1 5.2 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 DUF373 PF04123.13 EGO61266.1 - 1.5 8.2 4.8 2.3 7.6 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Pkinase PF00069.25 EGO61267.1 - 4.9e-62 209.7 0.0 1.2e-61 208.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO61267.1 - 4.7e-31 108.0 0.0 6.9e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGO61267.1 - 0.0002 20.8 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGO61267.1 - 0.021 13.8 0.1 2.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain TFIIE-A_C PF11521.8 EGO61267.1 - 0.13 12.6 0.1 0.24 11.7 0.1 1.4 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Sec10 PF07393.11 EGO61268.1 - 8.6e-170 566.6 0.0 6.1e-169 563.8 0.0 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 EGO61268.1 - 4.1e-09 36.2 0.7 1.2e-08 34.7 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGO61268.1 - 1.6e-07 31.0 0.2 3.3e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGO61268.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 F-box HTH_12 PF08461.10 EGO61268.1 - 0.081 12.9 0.6 0.27 11.2 0.6 1.9 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Glyco_hydro_63 PF03200.16 EGO61269.1 - 2.4e-172 574.1 4.0 4.1e-172 573.4 0.3 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EGO61269.1 - 2.3e-82 276.5 0.1 2.3e-82 276.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 EGO61269.1 - 0.00068 18.7 0.0 0.0017 17.4 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 EGO61269.1 - 0.014 14.3 0.2 0.035 13.0 0.2 1.6 1 0 0 1 1 1 0 Trehalase CDC45 PF02724.14 EGO61270.1 - 0.016 13.6 0.2 0.032 12.5 0.2 1.7 1 1 0 1 1 1 0 CDC45-like protein bZIP_1 PF00170.21 EGO61270.1 - 0.47 10.6 5.1 0.96 9.6 5.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor IGR PF09597.10 EGO61271.1 - 2.6e-25 88.3 0.2 4.6e-25 87.5 0.2 1.4 1 0 0 1 1 1 1 IGR protein motif SAM_1 PF00536.30 EGO61271.1 - 0.015 15.7 0.0 0.028 14.9 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SNF2_N PF00176.23 EGO61272.1 - 9.9e-53 179.1 0.0 1.7e-52 178.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 EGO61272.1 - 1.1e-08 34.8 9.1 2.1e-08 33.9 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGO61272.1 - 1.3e-08 35.0 11.9 2.5e-08 34.1 11.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGO61272.1 - 7.1e-08 32.2 11.8 1.5e-07 31.1 11.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGO61272.1 - 1.6e-06 27.9 11.2 3e-06 27.0 11.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGO61272.1 - 5.5e-05 23.0 11.0 0.0001 22.2 11.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGO61272.1 - 5.8e-05 23.3 8.7 0.00016 21.9 8.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGO61272.1 - 0.00012 22.1 7.9 0.00014 21.9 5.3 2.2 1 1 1 2 2 2 1 RING-type zinc-finger Helicase_C PF00271.31 EGO61272.1 - 0.00021 21.6 0.0 0.00047 20.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 EGO61272.1 - 0.00063 19.6 11.2 0.0012 18.7 11.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-P11 PF03854.14 EGO61272.1 - 0.09 12.5 6.5 0.31 10.7 6.5 1.9 1 1 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 EGO61272.1 - 0.12 12.6 10.9 0.23 11.6 10.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Glu-tRNAGln PF02686.15 EGO61272.1 - 0.17 12.2 2.1 0.68 10.3 0.5 2.9 3 0 0 3 3 2 0 Glu-tRNAGln amidotransferase C subunit zf-RING_6 PF14835.6 EGO61272.1 - 0.26 11.2 4.0 0.64 9.9 4.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EGO61272.1 - 0.54 10.1 8.0 0.28 11.0 4.9 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGO61272.1 - 0.92 9.6 4.5 2 8.5 4.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 EGO61272.1 - 1.8 8.6 5.8 7.1 6.7 5.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon Vps39_2 PF10367.9 EGO61272.1 - 2.3 8.7 5.7 3.3 8.2 0.5 2.7 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Malic_M PF03949.15 EGO61273.1 - 8.4e-99 330.0 0.0 1.3e-98 329.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EGO61273.1 - 4e-72 241.8 0.0 7.5e-72 241.0 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Suv3_N PF18114.1 EGO61273.1 - 0.18 11.9 0.1 0.56 10.3 0.0 1.8 2 0 0 2 2 2 0 Suv3 helical N-terminal domain SNF2_N PF00176.23 EGO61274.1 - 7.5e-51 172.9 1.0 1.1e-46 159.2 0.1 2.5 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EGO61274.1 - 7.5e-16 58.5 0.0 3.4e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO61274.1 - 5.3e-08 33.1 0.4 1.4e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EGO61274.1 - 3e-05 23.8 13.4 3e-05 23.8 13.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGO61274.1 - 0.0042 16.9 12.0 0.0042 16.9 12.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 EGO61274.1 - 0.0046 15.9 0.2 0.021 13.7 0.0 2.2 3 0 0 3 3 3 1 P-loop containing NTP hydrolase pore-1 zf-RING_2 PF13639.6 EGO61274.1 - 0.01 16.1 13.8 0.01 16.1 13.8 2.5 2 1 0 2 2 2 0 Ring finger domain AT_hook PF02178.19 EGO61274.1 - 0.1 12.5 6.8 0.53 10.3 6.8 2.3 1 0 0 1 1 1 0 AT hook motif zf-C3HC4_2 PF13923.6 EGO61274.1 - 1.1 9.2 19.4 0.038 13.8 12.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) LRR_4 PF12799.7 EGO61275.1 - 7.7e-06 26.2 0.7 2.5 8.7 0.0 5.1 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGO61275.1 - 0.00034 20.4 1.6 16 5.8 0.0 5.7 6 0 0 6 6 6 2 Leucine Rich repeat GATA PF00320.27 EGO61275.1 - 0.0043 16.6 1.0 0.013 15.1 1.0 1.8 1 0 0 1 1 1 1 GATA zinc finger NinF PF05810.12 EGO61275.1 - 0.13 12.1 2.3 11 5.9 0.0 3.7 3 1 1 4 4 4 0 NinF protein PGA2 PF07543.12 EGO61275.1 - 0.23 11.4 5.1 1.7 8.6 6.3 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 RecO_C PF02565.15 EGO61275.1 - 0.37 10.6 1.7 0.43 10.4 0.2 1.8 2 0 0 2 2 2 0 Recombination protein O C terminal Dicty_REP PF05086.12 EGO61275.1 - 0.97 7.3 4.6 1.4 6.8 4.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4939 PF16297.5 EGO61276.1 - 0.089 12.7 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4939) DUF5314 PF17241.2 EGO61276.1 - 0.09 12.4 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5314) DUF1793 PF08760.11 EGO61279.1 - 2.9e-74 249.0 2.1 5.4e-74 248.2 0.2 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 EGO61279.1 - 2.2e-66 222.8 1.6 1.3e-51 174.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EGO61279.1 - 1.3e-37 129.8 0.1 2e-37 129.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 EGO61279.1 - 0.034 13.7 0.1 0.075 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) Meiosis_expr PF15163.6 EGO61279.1 - 0.044 14.5 4.1 0.42 11.3 0.1 2.7 2 0 0 2 2 2 0 Meiosis-expressed Eisosome1 PF12757.7 EGO61280.1 - 1e-39 135.6 14.3 1e-39 135.6 14.3 4.4 4 1 0 4 4 4 1 Eisosome protein 1 Aminotran_3 PF00202.21 EGO61280.1 - 3.2 6.3 9.8 0.056 12.1 2.7 1.6 2 0 0 2 2 2 0 Aminotransferase class-III WSC PF01822.19 EGO61281.1 - 4.3e-35 119.7 31.6 5.1e-19 68.2 10.4 3.2 3 0 0 3 3 3 2 WSC domain peroxidase PF00141.23 EGO61281.1 - 8e-24 84.6 0.1 2e-23 83.3 0.1 1.6 1 0 0 1 1 1 1 Peroxidase GAS2 PF02187.17 EGO61282.1 - 1.1e-05 25.4 0.1 2.4e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Fungal_trans PF04082.18 EGO61284.1 - 5.7e-31 107.5 0.0 8.7e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO61284.1 - 2.5e-06 27.5 10.0 5e-06 26.5 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPATA48 PF15073.6 EGO61284.1 - 0.023 15.0 0.8 0.053 13.8 0.8 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 ORC6 PF05460.13 EGO61284.1 - 0.22 10.7 7.1 0.55 9.4 7.1 1.6 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FAM176 PF14851.6 EGO61286.1 - 0.51 10.0 10.9 0.52 10.0 10.9 1.0 1 0 0 1 1 1 0 FAM176 family Comm PF15957.5 EGO61286.1 - 1.4 9.3 6.8 1.4 9.2 6.8 1.1 1 0 0 1 1 1 0 Commissureless CRF1 PF10380.9 EGO61286.1 - 1.9 8.9 8.9 1.9 8.8 8.9 1.0 1 0 0 1 1 1 0 Transcription factor CRF1 MTABC_N PF16185.5 EGO61286.1 - 2.7 7.4 7.3 2.7 7.4 7.3 1.0 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region DUF4834 PF16118.5 EGO61286.1 - 3 8.9 20.4 4 8.5 20.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Connexin PF00029.19 EGO61286.1 - 3.3 7.4 13.2 3.2 7.4 13.2 1.0 1 0 0 1 1 1 0 Connexin Rxt3 PF08642.10 EGO61286.1 - 4.9 7.9 9.9 5.4 7.8 9.9 1.1 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Presenilin PF01080.17 EGO61286.1 - 5 5.8 18.1 5 5.8 18.1 1.0 1 0 0 1 1 1 0 Presenilin TMEM51 PF15345.6 EGO61286.1 - 6.1 6.6 20.9 5.8 6.7 20.9 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 SpoIIP PF07454.11 EGO61286.1 - 6.1 6.2 18.7 6.2 6.2 18.7 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) G0-G1_switch_2 PF15103.6 EGO61286.1 - 8.7 6.8 12.7 9.3 6.7 12.7 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 Glyco_hydro_3_C PF01915.22 EGO61287.1 - 5.9e-48 163.5 0.0 1.6e-47 162.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGO61287.1 - 4.9e-35 121.4 0.0 2.5e-33 115.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGO61287.1 - 7.2e-19 67.7 0.1 1.3e-18 66.9 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Lipase_3 PF01764.25 EGO61288.1 - 1.3e-39 135.3 0.1 2.4e-39 134.5 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 EGO61288.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.12 EGO61288.1 - 0.002 17.8 1.0 0.0034 17.0 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase Hydrolase_4 PF12146.8 EGO61288.1 - 0.0021 17.4 0.1 0.0044 16.3 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGO61288.1 - 0.034 13.9 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 EGO61288.1 - 0.048 13.2 0.6 0.81 9.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 EGO61288.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO61288.1 - 0.063 13.9 0.1 0.083 13.5 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 EGO61288.1 - 0.11 12.5 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain Ribosomal_L34 PF00468.17 EGO61289.1 - 7e-13 48.3 8.0 1.2e-12 47.6 8.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Peptidase_M48_N PF16491.5 EGO61290.1 - 1.4e-65 220.6 11.5 1.4e-65 220.6 11.5 1.8 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EGO61290.1 - 3.1e-46 157.7 0.1 6.2e-46 156.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EGO61290.1 - 0.00089 18.5 0.2 0.0018 17.6 0.2 1.5 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF1772 PF08592.11 EGO61290.1 - 0.026 14.9 0.1 0.065 13.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF4538 PF15061.6 EGO61290.1 - 0.59 9.9 5.2 0.1 12.3 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Ish1 PF10281.9 EGO61291.1 - 4.7e-05 23.6 0.2 7.1e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein DUF3487 PF11990.8 EGO61291.1 - 0.08 12.8 0.0 0.089 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DNA_meth_N PF18284.1 EGO61291.1 - 0.2 11.6 1.9 0.36 10.8 1.7 1.6 1 1 0 1 1 1 0 DNA methylase N-terminal domain Ribosomal_L38e PF01781.18 EGO61292.1 - 5.9e-33 112.8 3.6 7.2e-33 112.5 3.6 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family GHMP_kinases_N PF00288.26 EGO61294.1 - 1.9e-15 56.9 0.0 4.1e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGO61294.1 - 7.2e-08 32.7 0.0 1.6e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EGO61294.1 - 0.002 17.6 0.0 0.005 16.4 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.22 EGO61295.1 - 1.9e-35 119.5 15.9 4.1e-07 29.5 0.1 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Val_tRNA-synt_C PF10458.9 EGO61296.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm PGA2 PF07543.12 EGO61297.1 - 7.1e-43 145.9 2.6 8.7e-43 145.6 2.6 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 CENP-B_dimeris PF09026.10 EGO61297.1 - 3.8 8.0 7.7 17 5.9 1.3 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CENP-S PF15630.6 EGO61298.1 - 2.9e-34 117.3 0.1 4.2e-34 116.8 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGO61298.1 - 4.7e-09 36.3 0.1 5.6e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 EGO61298.1 - 0.016 15.2 0.1 0.021 14.9 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TAF PF02969.17 EGO61298.1 - 0.018 15.2 0.1 0.17 12.1 0.0 2.2 1 1 1 2 2 2 0 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 EGO61298.1 - 0.04 13.9 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Amelotin PF15757.5 EGO61298.1 - 0.079 12.5 0.0 0.093 12.3 0.0 1.1 1 0 0 1 1 1 0 Amelotin Utp13 PF08625.11 EGO61299.1 - 1.1e-50 171.2 0.1 1.9e-50 170.5 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 EGO61299.1 - 2.2e-45 151.7 7.5 1.7e-07 31.8 0.0 12.2 11 2 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGO61299.1 - 3.6e-15 56.0 2.3 0.028 14.7 0.0 8.0 5 2 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGO61299.1 - 0.0002 20.1 1.3 0.16 10.6 0.0 4.1 4 0 0 4 4 4 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGO61299.1 - 0.015 14.2 0.0 28 3.5 0.0 3.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGO61299.1 - 0.045 13.1 0.0 7.9 5.7 0.0 3.7 4 0 0 4 4 4 0 WD40-like domain SOG2 PF10428.9 EGO61300.1 - 4.5 6.3 15.5 6.3 5.9 15.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 EGO61301.1 - 0.18 10.3 8.1 0.25 9.9 8.1 1.1 1 0 0 1 1 1 0 Macoilin family PAP1 PF08601.10 EGO61301.1 - 0.99 9.1 16.5 1.6 8.3 16.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 LSM PF01423.22 EGO61302.1 - 8.5e-12 44.6 0.4 4.9e-07 29.4 0.1 2.3 2 0 0 2 2 2 2 LSM domain UQ_con PF00179.26 EGO61304.1 - 1e-50 171.0 0.0 1.2e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TPR_2 PF07719.17 EGO61305.1 - 4.4e-06 26.4 2.1 1.2 9.5 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGO61305.1 - 0.00011 21.8 0.5 3.8 7.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGO61305.1 - 0.0037 17.5 3.5 0.075 13.3 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat UBA PF00627.31 EGO61305.1 - 0.0078 16.1 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DnaJ PF00226.31 EGO61305.1 - 0.024 14.8 0.2 0.091 12.9 0.0 2.0 2 0 0 2 2 2 0 DnaJ domain TPR_16 PF13432.6 EGO61305.1 - 0.042 14.5 7.1 18 6.1 0.7 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Exonuc_VII_L PF02601.15 EGO61305.1 - 2.7 7.5 6.7 1.6 8.2 0.1 3.0 3 0 0 3 3 3 0 Exonuclease VII, large subunit PIEZO PF15917.5 EGO61305.1 - 6.2 6.2 6.7 1.1 8.7 1.3 2.3 2 0 0 2 2 2 0 Piezo Mcp5_PH PF12814.7 EGO61306.1 - 4.1e-47 159.3 0.0 4.1e-47 159.3 0.0 1.8 2 0 0 2 2 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 EGO61306.1 - 0.00011 22.7 16.5 0.00025 21.6 16.5 1.5 1 0 0 1 1 1 1 Fez1 Macoilin PF09726.9 EGO61306.1 - 0.15 10.5 12.0 0.4 9.2 12.0 1.6 1 0 0 1 1 1 0 Macoilin family DUF724 PF05266.14 EGO61306.1 - 0.27 11.0 9.1 0.62 9.9 9.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.12 EGO61306.1 - 0.8 9.8 24.8 0.22 11.6 13.2 2.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 EGO61306.1 - 0.83 9.7 19.1 2.4 8.2 19.1 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 EGO61306.1 - 0.92 8.9 18.6 1.6 8.1 18.6 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3437 PF11919.8 EGO61306.1 - 1.9 8.5 5.0 3.1 7.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Exonuc_VII_L PF02601.15 EGO61306.1 - 2.8 7.4 8.6 5.2 6.5 8.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 EGO61306.1 - 3.1 6.6 17.4 5.2 5.9 17.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 EGO61306.1 - 4.6 6.2 12.1 9.1 5.3 12.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 EGO61306.1 - 7.4 5.8 9.9 13 5.1 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hydrolase PF00702.26 EGO61310.1 - 1.2e-06 29.0 0.0 1.9e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGO61310.1 - 1.3e-06 28.6 0.0 1.6e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO61310.1 - 0.0019 18.2 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Opy2 PF09463.10 EGO61312.1 - 3.9e-09 36.7 14.0 6.3e-09 36.0 14.0 1.4 1 0 0 1 1 1 1 Opy2 protein Mid2 PF04478.12 EGO61312.1 - 0.012 15.5 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.10 EGO61312.1 - 0.047 13.1 1.6 0.11 12.0 1.6 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-ANAPC11 PF12861.7 EGO61312.1 - 0.088 12.9 2.6 0.16 12.0 2.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Chitin_synth_1 PF01644.17 EGO61313.1 - 1.5e-67 226.6 0.0 2.2e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EGO61313.1 - 2.2e-27 94.8 0.1 3.9e-27 94.0 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EGO61313.1 - 3.7e-25 88.5 0.2 6.1e-21 74.6 0.0 2.6 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGO61313.1 - 2.9e-07 30.6 10.1 8.2e-06 25.9 10.1 2.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 UQ_con PF00179.26 EGO61314.1 - 5e-37 126.7 0.0 6.5e-37 126.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGO61314.1 - 0.081 12.6 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B IlvN PF07991.12 EGO61315.1 - 3.8e-46 156.7 0.0 6.3e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EGO61315.1 - 1.3e-39 135.7 0.0 2.1e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 EGO61315.1 - 0.042 14.4 0.0 0.13 12.8 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EGO61315.1 - 0.085 13.0 0.0 0.21 11.8 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase PALP PF00291.25 EGO61316.1 - 1.3e-62 211.9 0.0 1.6e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3343 PF11823.8 EGO61316.1 - 0.064 12.7 0.8 0.31 10.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3343) Transglut_core PF01841.19 EGO61316.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily Rep_fac-A_C PF08646.10 EGO61317.1 - 2.7e-59 199.1 2.9 1e-57 194.0 1.3 2.4 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EGO61317.1 - 1.8e-38 130.4 0.6 5e-38 128.9 0.3 1.9 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 EGO61317.1 - 1.3e-21 76.5 0.1 2.9e-21 75.4 0.1 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EGO61317.1 - 7.9e-18 64.2 2.3 1.3e-11 44.3 0.0 4.5 4 1 1 5 5 5 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 EGO61317.1 - 5.5e-06 26.3 0.5 0.00096 18.9 0.0 3.1 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DUF4539 PF15072.6 EGO61317.1 - 0.011 15.7 0.2 6.4 6.9 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4539) zf-like PF04071.12 EGO61317.1 - 0.036 14.0 0.3 0.083 12.8 0.3 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain POT1 PF02765.17 EGO61317.1 - 0.064 13.1 0.5 1.2 8.9 0.0 2.6 3 0 0 3 3 3 0 Telomeric single stranded DNA binding POT1/CDC13 Amidohydro_2 PF04909.14 EGO61318.1 - 1.7e-38 133.1 0.7 1.9e-38 132.9 0.7 1.0 1 0 0 1 1 1 1 Amidohydrolase DUF3099 PF11298.8 EGO61318.1 - 0.06 13.5 0.9 0.11 12.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) Cyt-b5 PF00173.28 EGO61320.1 - 1.5e-22 79.5 0.3 1.6e-22 79.4 0.3 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 EGO61320.1 - 0.09 12.9 0.0 0.69 10.0 0.0 2.0 1 1 1 2 2 2 0 V-ATPase subunit H SUR7 PF06687.12 EGO61322.1 - 4.3e-32 111.5 16.0 5.2e-32 111.2 16.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 EGO61322.1 - 0.0077 16.2 10.4 0.013 15.4 10.4 1.4 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 AMPK1_CBM PF16561.5 EGO61324.1 - 9e-05 22.6 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_20 PF00686.19 EGO61324.1 - 0.14 12.0 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Starch binding domain Fer2 PF00111.27 EGO61325.1 - 0.015 15.3 1.1 0.051 13.5 0.2 2.1 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain RXT2_N PF08595.11 EGO61325.1 - 0.018 15.1 0.4 0.031 14.3 0.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Tub_N PF16322.5 EGO61325.1 - 0.036 14.5 1.5 0.036 14.5 1.5 2.1 1 1 0 2 2 2 0 Tubby N-terminal PI3K_1B_p101 PF10486.9 EGO61325.1 - 0.15 9.8 0.5 0.2 9.4 0.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Cwf_Cwc_15 PF04889.12 EGO61325.1 - 0.61 9.8 4.6 1.1 8.9 4.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 EGO61325.1 - 1.2 9.6 8.4 2.1 8.8 8.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 EGO61325.1 - 7.3 7.0 8.2 20 5.7 8.2 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFAP1 PF06991.11 EGO61326.1 - 1.1e-74 250.9 33.7 1.1e-74 250.9 33.7 3.2 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing Pol_alpha_B_N PF08418.10 EGO61327.1 - 7e-80 268.5 0.0 9e-80 268.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 EGO61327.1 - 4.1e-47 160.3 0.0 5.6e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CRAL_TRIO PF00650.20 EGO61328.1 - 1.1e-45 155.2 0.0 1.4e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGO61328.1 - 2.8e-17 62.7 0.9 2.8e-17 62.7 0.9 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGO61328.1 - 0.0048 17.1 0.0 0.0075 16.4 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Homeodomain PF00046.29 EGO61331.1 - 6.3e-20 70.8 4.5 1.3e-19 69.8 4.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGO61331.1 - 0.002 18.0 0.5 0.0047 16.8 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF3827 PF12877.7 EGO61331.1 - 0.25 9.7 7.8 0.36 9.1 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Ndc1_Nup PF09531.10 EGO61331.1 - 1.5 7.5 3.5 2 7.0 3.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tho2 PF11262.8 EGO61331.1 - 2.3 7.3 4.6 3.3 6.8 4.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PhoLip_ATPase_C PF16212.5 EGO61333.1 - 6.3e-71 239.0 20.3 6.3e-71 239.0 20.3 1.6 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGO61333.1 - 3.6e-24 84.2 2.6 1.1e-22 79.5 0.4 2.9 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGO61333.1 - 2.7e-12 47.4 0.0 0.0001 22.7 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGO61333.1 - 7.5e-12 45.1 0.1 2e-11 43.7 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGO61333.1 - 1.2e-11 44.5 0.0 3e-10 40.0 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGO61333.1 - 0.0017 18.2 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2759 PF10958.8 EGO61333.1 - 4.9 6.9 8.0 0.54 10.0 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) ABC_tran PF00005.27 EGO61334.1 - 4.1e-52 176.3 0.0 1.4e-29 103.3 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 EGO61334.1 - 3.3e-51 174.5 22.7 9.3e-30 104.2 8.4 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EGO61334.1 - 2.2e-10 40.4 1.7 0.002 17.6 0.1 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGO61334.1 - 9.9e-09 36.0 0.4 4.2e-05 24.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGO61334.1 - 7.1e-06 26.5 2.0 0.041 14.3 0.0 3.7 4 0 0 4 4 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGO61334.1 - 1.7e-05 24.8 0.1 0.047 13.6 0.1 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGO61334.1 - 5.5e-05 22.8 0.3 0.19 11.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGO61334.1 - 9.7e-05 22.3 0.5 1.3 8.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EGO61334.1 - 0.0001 22.3 0.0 0.11 12.6 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EGO61334.1 - 0.00022 21.0 0.2 0.092 12.5 0.0 2.7 3 0 0 3 3 3 1 IstB-like ATP binding protein T2SSE PF00437.20 EGO61334.1 - 0.00041 19.5 0.0 0.38 9.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 EGO61334.1 - 0.0014 18.9 1.0 5 7.4 0.1 3.9 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.6 EGO61334.1 - 0.0017 18.0 0.0 0.26 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGO61334.1 - 0.0021 17.6 1.3 4.5 6.7 0.1 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_15 PF13175.6 EGO61334.1 - 0.008 15.9 0.1 0.41 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Adeno_IVa2 PF02456.15 EGO61334.1 - 0.027 13.3 0.2 0.071 11.9 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein RNA_helicase PF00910.22 EGO61334.1 - 0.034 14.5 0.4 5 7.6 0.1 3.1 3 0 0 3 3 2 0 RNA helicase DUF87 PF01935.17 EGO61334.1 - 0.047 13.8 1.7 0.26 11.3 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 EGO61334.1 - 0.068 12.3 0.1 6.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 EGO61334.1 - 0.07 12.8 2.6 5.7 6.6 0.0 3.5 4 0 0 4 4 3 0 AAA domain Zeta_toxin PF06414.12 EGO61334.1 - 0.089 12.1 0.1 16 4.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 EGO61334.1 - 0.095 12.6 0.8 0.66 9.8 0.0 2.7 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea AAA PF00004.29 EGO61334.1 - 0.15 12.4 0.7 10 6.5 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 EGO61334.1 - 6.8 6.7 7.5 8 6.5 0.0 3.6 5 0 0 5 5 3 0 Dynamin family Adaptin_binding PF10199.9 EGO61336.1 - 1.9e-11 44.6 21.6 4.1e-11 43.5 17.4 2.9 2 2 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Voldacs PF03517.13 EGO61338.1 - 1.7e-21 76.8 0.1 4.4e-21 75.4 0.1 1.7 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling SAT PF16073.5 EGO61342.1 - 3.9e-81 272.3 3.1 2.1e-77 260.1 0.0 2.9 3 0 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 EGO61342.1 - 2.6e-76 256.5 0.0 8.3e-76 254.9 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGO61342.1 - 1.4e-46 159.5 0.1 3.1e-46 158.3 0.1 1.5 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGO61342.1 - 1e-35 122.3 0.6 2.8e-35 120.9 0.6 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EGO61342.1 - 1.6e-25 89.3 3.2 2.3e-13 50.3 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 EGO61342.1 - 1.6e-24 87.3 0.0 3.3e-23 83.0 0.0 2.9 2 1 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 EGO61342.1 - 1.7e-14 53.8 0.0 2.9e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGO61342.1 - 5.5e-06 26.8 0.0 2.3e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 EGO61342.1 - 1.1e-05 26.1 0.1 0.051 14.2 0.0 3.0 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.23 EGO61342.1 - 0.00012 21.5 0.1 0.007 15.7 0.0 2.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Hydrolase_4 PF12146.8 EGO61342.1 - 0.0024 17.2 0.1 0.26 10.5 0.0 2.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Zn_clus PF00172.18 EGO61344.1 - 3.2e-06 27.1 17.0 3.2e-06 27.1 17.0 1.9 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EGO61344.1 - 0.00031 21.0 12.0 0.0035 17.7 1.2 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type DUF4187 PF13821.6 EGO61344.1 - 0.0031 17.3 0.1 0.0071 16.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-H2C2_2 PF13465.6 EGO61344.1 - 0.0093 16.4 0.9 0.0093 16.4 0.9 4.4 4 1 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGO61344.1 - 0.01 16.6 11.4 0.019 15.8 2.9 3.1 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EGO61344.1 - 0.14 11.9 0.4 0.14 11.9 0.4 3.3 3 1 0 3 3 3 0 zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 EGO61344.1 - 0.25 11.0 4.2 0.095 12.4 0.7 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF92 PF01940.16 EGO61347.1 - 4.1e-76 255.5 2.5 5.7e-76 255.0 2.5 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Pkinase PF00069.25 EGO61348.1 - 2.8e-76 256.4 0.0 4.3e-76 255.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO61348.1 - 3.6e-38 131.3 0.0 5.8e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EGO61348.1 - 5.5e-21 75.2 2.9 1.4e-11 44.9 0.5 3.1 2 1 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 EGO61348.1 - 3.2e-15 55.9 0.5 6.9e-15 54.9 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 EGO61348.1 - 2.9e-05 23.5 0.0 5.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGO61348.1 - 0.00066 19.3 0.3 0.0013 18.3 0.3 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EGO61348.1 - 0.0034 16.4 0.2 0.0061 15.6 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 EGO61348.1 - 0.0045 15.9 0.1 0.0071 15.2 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 EGO61348.1 - 0.09 12.7 0.8 0.29 11.0 0.4 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family MFS_1 PF07690.16 EGO61349.1 - 3.4e-33 115.1 27.6 4.2e-33 114.7 27.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Hydantoinase_B PF02538.14 EGO61350.1 - 5.5e-190 632.2 1.5 1.9e-183 610.6 0.3 2.2 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EGO61350.1 - 3.4e-102 341.6 1.0 3.4e-102 341.6 1.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EGO61350.1 - 8.2e-63 211.3 2.6 1.4e-61 207.3 0.1 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region NAGidase PF07555.13 EGO61350.1 - 0.16 11.3 0.0 0.48 9.7 0.0 1.8 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase ADIP PF11559.8 EGO61351.1 - 1.9e-43 148.2 8.0 1.9e-43 148.2 8.0 3.4 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding Adeno_E4 PF05385.11 EGO61352.1 - 0.37 10.9 3.4 0.48 10.5 1.1 1.9 1 1 1 2 2 2 0 Mastadenovirus early E4 13 kDa protein RRP7 PF12923.7 EGO61353.1 - 3.3e-31 107.9 14.6 3.3e-31 107.9 14.6 1.9 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 EGO61353.1 - 2.5e-20 72.9 0.0 5.1e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain Peptidase_M17_N PF02789.17 EGO61353.1 - 1.9 8.4 6.2 0.93 9.4 3.5 1.9 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain DUF2567 PF10821.8 EGO61355.1 - 0.04 14.0 0.1 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) Retrotran_gag_3 PF14244.6 EGO61356.1 - 0.01 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_2 PF14223.6 EGO61356.1 - 0.028 14.1 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Elongin_A PF06881.11 EGO61356.1 - 0.048 14.2 0.7 0.12 13.0 0.2 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A MOSC PF03473.17 EGO61358.1 - 8.8e-26 90.5 0.0 1.9e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.27 EGO61358.1 - 1.5e-08 34.5 2.2 1.6e-07 31.2 3.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 EGO61358.1 - 1.4e-06 28.0 0.3 2.8e-06 27.1 0.3 1.4 1 0 0 1 1 1 1 3-alpha domain NAD_binding_1 PF00175.21 EGO61358.1 - 2.5e-05 24.9 0.1 0.00011 22.8 0.0 2.2 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain F-box PF00646.33 EGO61359.1 - 2.3e-06 27.3 1.2 5.6e-06 26.1 0.7 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EGO61359.1 - 0.00022 21.1 0.2 0.0005 19.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EGO61359.1 - 0.02 14.8 0.1 0.062 13.2 0.1 1.9 1 0 0 1 1 1 0 F-box B_lectin PF01453.24 EGO61359.1 - 0.043 14.4 0.0 0.19 12.3 0.0 2.0 2 0 0 2 2 2 0 D-mannose binding lectin Peptidase_S24 PF00717.23 EGO61359.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase S24-like CLP_protease PF00574.23 EGO61361.1 - 2.5e-69 232.8 0.1 3.3e-69 232.4 0.1 1.1 1 0 0 1 1 1 1 Clp protease TGF_beta_GS PF08515.12 EGO61361.1 - 0.4 10.2 4.8 0.11 12.0 1.4 1.8 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif ILVD_EDD PF00920.21 EGO61362.1 - 4.2e-214 711.9 0.0 4.9e-214 711.7 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Kinesin PF00225.23 EGO61364.1 - 1.6e-104 349.4 2.9 1.6e-104 349.4 2.9 2.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGO61364.1 - 9.9e-55 184.6 0.8 3.3e-54 182.9 0.1 2.3 2 0 0 2 2 2 1 Microtubule binding AAA_24 PF13479.6 EGO61364.1 - 0.0018 18.0 0.1 0.0088 15.8 0.1 2.2 1 0 0 1 1 1 1 AAA domain RuBisCO_large PF00016.20 EGO61364.1 - 0.021 14.0 0.1 0.041 13.1 0.1 1.4 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain AAA_16 PF13191.6 EGO61364.1 - 0.11 12.8 0.0 0.11 12.8 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain DUF1993 PF09351.10 EGO61364.1 - 3.5 7.7 17.5 1.6 8.9 1.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) YabA PF06156.13 EGO61364.1 - 6.1 7.5 48.3 0.29 11.8 9.2 6.2 3 1 3 6 6 6 0 Initiation control protein YabA Acetyltransf_3 PF13302.7 EGO61365.1 - 2.1e-12 47.9 0.0 3.9e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGO61365.1 - 4.5e-11 43.0 0.1 2e-10 40.9 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGO61365.1 - 0.00036 20.9 0.0 0.00058 20.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGO61365.1 - 0.0066 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGO61365.1 - 0.026 14.7 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGO61365.1 - 0.046 13.7 0.1 0.12 12.3 0.1 1.7 1 1 0 1 1 1 0 FR47-like protein PC4 PF02229.16 EGO61366.1 - 2.9e-20 71.6 0.0 5.2e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) PXA PF02194.15 EGO61367.1 - 2.6e-34 118.8 0.2 8.6e-34 117.1 0.0 2.0 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 EGO61367.1 - 6.6e-25 87.9 0.0 6.2e-24 84.7 0.0 2.7 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 EGO61367.1 - 1.4e-06 28.2 0.0 1.4e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 PX domain DUF768 PF05589.11 EGO61368.1 - 0.18 11.8 0.3 18 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF768) DNA_pol_E_B PF04042.16 EGO61370.1 - 3.5e-75 252.0 0.0 5.6e-75 251.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SIN1 PF05422.12 EGO61370.1 - 0.3 11.7 0.6 0.64 10.6 0.6 1.5 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) HET PF06985.11 EGO61371.1 - 1.6e-10 41.5 2.1 3.5e-10 40.4 2.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Bcr-Abl_Oligo PF09036.10 EGO61371.1 - 0.08 13.0 0.2 0.2 11.7 0.2 1.6 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Cu-oxidase_2 PF07731.14 EGO61372.1 - 4.5e-40 136.6 8.2 1.4e-37 128.5 0.9 3.7 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGO61372.1 - 6.9e-40 135.8 5.0 1.7e-37 128.1 0.3 3.6 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 EGO61372.1 - 4.1e-25 88.7 0.1 1.2e-23 84.0 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase adh_short PF00106.25 EGO61373.1 - 9e-32 110.1 0.0 1.2e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGO61373.1 - 2.1e-21 76.6 0.0 3.9e-21 75.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGO61373.1 - 8.2e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGO61373.1 - 0.00021 20.8 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EGO61373.1 - 0.017 15.1 0.1 0.036 14.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 EGO61373.1 - 0.02 14.0 0.1 0.032 13.3 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 EGO61373.1 - 0.17 11.3 0.1 0.34 10.3 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 EGO61374.1 - 9e-76 255.4 0.2 4e-75 253.2 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGO61374.1 - 0.00026 20.7 0.1 0.0022 17.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 EGO61374.1 - 0.0043 16.2 0.0 0.021 13.9 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.12 EGO61374.1 - 0.0066 15.5 0.1 0.14 11.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGO61374.1 - 0.0078 15.3 0.1 0.018 14.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain SUIM_assoc PF16619.5 EGO61374.1 - 0.013 15.5 4.2 0.032 14.3 4.2 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 3HCDH_N PF02737.18 EGO61374.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EGO61374.1 - 0.014 14.7 0.0 0.029 13.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGO61374.1 - 0.014 14.6 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EGO61374.1 - 0.015 15.5 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.6 EGO61374.1 - 0.03 14.5 0.0 0.093 13.0 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 EGO61374.1 - 0.045 13.4 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 EGO61374.1 - 0.089 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 ThiF family PT-TG PF14449.6 EGO61374.1 - 0.59 10.1 2.5 1.7 8.6 0.5 2.7 3 0 0 3 3 3 0 Pre-toxin TG PNRC PF15365.6 EGO61374.1 - 3.6 7.5 8.0 7.2 6.6 8.0 1.5 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif HET PF06985.11 EGO61376.1 - 8.2e-29 100.8 0.3 8.2e-29 100.8 0.3 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF4175 PF13779.6 EGO61376.1 - 1.4 6.7 6.3 1.9 6.3 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CMD PF02627.20 EGO61377.1 - 1.8e-10 40.7 0.0 6.1e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family PRMT5_C PF17286.2 EGO61377.1 - 0.15 11.9 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 PRMT5 oligomerisation domain APH PF01636.23 EGO61378.1 - 1.4e-08 35.0 0.5 0.0025 17.8 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EGO61378.1 - 3.2e-08 33.2 0.9 6.1e-06 25.7 0.3 2.9 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EGO61378.1 - 1.4e-07 31.1 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO61378.1 - 0.00028 20.3 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EGO61378.1 - 0.00039 20.1 0.1 0.0029 17.2 0.0 2.3 2 1 0 2 2 2 1 RIO1 family EcKinase PF02958.20 EGO61378.1 - 0.058 12.7 0.0 0.53 9.5 0.0 2.0 2 0 0 2 2 2 0 Ecdysteroid kinase Pkinase_fungal PF17667.1 EGO61378.1 - 0.061 12.1 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Aldo_ket_red PF00248.21 EGO61379.1 - 1.8e-07 30.7 0.0 3.8e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 Aldo/keto reductase family Clat_adaptor_s PF01217.20 EGO61380.1 - 5.9e-52 175.4 1.3 6.9e-52 175.2 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 EGO61380.1 - 0.017 15.8 0.1 0.03 15.1 0.1 1.5 1 0 0 1 1 1 0 Pullulanase N1-terminal domain Maf1 PF09174.10 EGO61382.1 - 4.5e-60 202.8 0.0 6.9e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 Maf1 regulator DUF1694 PF07997.11 EGO61382.1 - 0.18 11.9 0.0 0.8 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1694) SDA1 PF05285.12 EGO61382.1 - 6.9 6.0 9.9 14 5.0 8.6 1.8 2 0 0 2 2 2 0 SDA1 DUF1712 PF08217.11 EGO61384.1 - 3.2e-12 45.8 0.0 6.6e-09 34.8 0.0 3.2 3 0 0 3 3 3 3 Fungal domain of unknown function (DUF1712) PP2C PF00481.21 EGO61385.1 - 7.9e-83 278.0 0.0 7.9e-83 278.0 0.0 1.4 2 0 0 2 2 2 1 Protein phosphatase 2C He_PIG PF05345.12 EGO61386.1 - 1.5e-15 57.1 16.4 2.4e-05 24.4 1.3 6.8 6 2 0 6 6 6 4 Putative Ig domain LapA_dom PF06305.11 EGO61386.1 - 0.07 13.0 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Methyltransf_16 PF10294.9 EGO61387.1 - 1.2e-44 152.1 0.0 1.4e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Lysine methyltransferase DPBB_1 PF03330.18 EGO61388.1 - 0.0015 18.8 0.0 0.0036 17.6 0.0 1.8 1 0 0 1 1 1 1 Lytic transglycolase MSP1_C PF07462.11 EGO61388.1 - 7.5 5.1 7.7 10 4.7 7.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Pex24p PF06398.11 EGO61389.1 - 4e-05 22.8 2.9 4e-05 22.8 2.9 1.8 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Corona_nucleoca PF00937.18 EGO61389.1 - 0.058 12.4 4.8 0.12 11.4 4.8 1.5 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein AAA_23 PF13476.6 EGO61389.1 - 2.8 8.4 5.0 19 5.7 5.0 2.1 1 1 0 1 1 1 0 AAA domain YtxH PF12732.7 EGO61390.1 - 6.9 7.3 9.7 13 6.4 8.5 1.9 1 1 1 2 2 2 0 YtxH-like protein ETRAMP PF09716.10 EGO61390.1 - 8.8 6.5 6.6 3.7 7.7 1.7 2.2 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) HTH_22 PF13309.6 EGO61391.1 - 0.0074 16.3 0.6 0.03 14.4 0.1 2.3 2 0 0 2 2 2 1 HTH domain Oxysterol_BP PF01237.18 EGO61392.1 - 2.9e-108 362.1 0.1 1.8e-107 359.4 0.1 1.9 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 EGO61392.1 - 8.5e-39 131.7 0.3 1.5e-37 127.8 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EGO61392.1 - 1.6e-06 28.5 0.0 4.1e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 PH domain GOLD_2 PF13897.6 EGO61392.1 - 0.34 11.4 0.0 0.34 11.4 0.0 1.9 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking SH2_2 PF14633.6 EGO61393.1 - 8.6e-88 293.3 0.1 8.6e-88 293.3 0.1 2.1 2 0 0 2 2 2 1 SH2 domain HTH_44 PF14641.6 EGO61393.1 - 4.7e-39 133.4 0.5 1.5e-38 131.8 0.5 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 EGO61393.1 - 1.6e-28 99.1 0.0 4.1e-28 97.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EGO61393.1 - 7.9e-28 97.1 0.0 2.6e-27 95.5 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 EGO61393.1 - 5.6e-19 68.5 31.2 5.6e-19 68.5 31.2 5.9 5 1 0 5 5 5 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 EGO61393.1 - 1.9e-06 28.7 1.8 1.9e-06 28.7 1.8 4.4 4 1 0 4 4 4 1 HHH domain SH2 PF00017.24 EGO61393.1 - 2.7e-06 27.4 0.0 7.2e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 SH2 domain S1 PF00575.23 EGO61393.1 - 7.4e-06 26.2 0.7 2.4e-05 24.6 0.7 1.9 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.7 EGO61393.1 - 4.5e-05 23.6 0.0 0.00017 21.8 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif PXB PF12828.7 EGO61393.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 PX-associated Pkinase PF00069.25 EGO61395.1 - 1.1e-65 221.7 0.0 1.4e-65 221.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGO61395.1 - 5.2e-40 137.4 0.0 6.9e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGO61395.1 - 0.00015 20.7 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGO61395.1 - 0.0019 17.5 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGO61395.1 - 0.0055 15.7 0.0 0.0078 15.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGO61395.1 - 0.069 12.7 0.2 0.88 9.1 0.1 2.1 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 EGO61395.1 - 0.092 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SopA_C PF13979.6 EGO61395.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 SopA-like catalytic domain HAD_2 PF13419.6 EGO61396.1 - 7.6e-15 55.4 0.0 4.7e-09 36.6 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGO61396.1 - 3.6e-10 40.5 1.2 0.061 13.6 0.0 3.4 1 1 3 4 4 4 3 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGO61396.1 - 6.8e-06 26.1 2.7 2.3e-05 24.3 2.3 2.1 1 1 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EGO61396.1 - 0.00066 20.1 0.4 0.017 15.5 0.4 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EGO61396.1 - 0.024 14.3 0.0 3.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase FUSC_2 PF13515.6 EGO61397.1 - 1.7e-26 92.8 9.4 1.7e-26 92.8 9.4 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC-like PF12805.7 EGO61397.1 - 0.00032 19.9 3.3 0.042 12.9 0.1 2.7 2 0 0 2 2 2 2 FUSC-like inner membrane protein yccS ArAE_2 PF10334.9 EGO61397.1 - 0.016 15.1 0.1 0.13 12.1 0.0 2.4 3 0 0 3 3 3 0 Aromatic acid exporter family member 2 ALMT PF11744.8 EGO61397.1 - 0.27 10.0 13.1 0.77 8.5 3.4 3.9 4 0 0 4 4 4 0 Aluminium activated malate transporter Response_reg PF00072.24 EGO61398.1 - 7.7e-28 96.9 0.2 1.4e-27 96.1 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EGO61398.1 - 6e-25 87.9 0.0 6.8e-19 68.4 0.0 2.9 3 0 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGO61398.1 - 5.3e-15 55.2 0.0 1.2e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EGO61398.1 - 0.0068 16.8 0.5 0.053 13.9 0.1 2.5 2 0 0 2 2 2 1 HAMP domain ORMDL PF04061.14 EGO61400.1 - 2.1e-58 196.0 3.8 2.5e-58 195.7 3.8 1.0 1 0 0 1 1 1 1 ORMDL family OST3_OST6 PF04756.13 EGO61400.1 - 0.16 11.3 0.1 0.16 11.3 0.1 1.6 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family PCYCGC PF13798.6 EGO61402.1 - 0.052 13.4 2.0 0.17 11.8 2.0 1.9 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif TERB2 PF15101.6 EGO61403.1 - 0.1 12.6 1.3 0.21 11.6 1.3 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Leu_zip PF15294.6 EGO61404.1 - 0.0066 16.0 1.1 0.0066 16.0 1.1 2.0 2 0 0 2 2 2 1 Leucine zipper TMF_DNA_bd PF12329.8 EGO61404.1 - 0.078 13.0 7.0 0.22 11.6 7.0 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding zf-C2H2_aberr PF17017.5 EGO61404.1 - 0.1 12.8 0.6 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger Shugoshin_N PF07558.11 EGO61404.1 - 0.35 10.8 7.5 0.077 12.9 3.4 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF349 PF03993.12 EGO61404.1 - 0.74 10.1 4.3 2.4 8.5 4.3 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) bZIP_2 PF07716.15 EGO61404.1 - 1.9 8.6 9.2 3.5 7.8 7.6 2.2 2 0 0 2 2 2 0 Basic region leucine zipper ERM PF00769.19 EGO61404.1 - 2.4 7.9 13.5 0.26 11.1 3.9 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DP PF08781.10 EGO61404.1 - 4.5 7.2 8.2 10 6.0 8.2 1.6 1 0 0 1 1 1 0 Transcription factor DP zf-C2H2 PF00096.26 EGO61404.1 - 4.8 7.8 21.9 0.62 10.6 1.4 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type Lipoxygenase PF00305.19 EGO61406.1 - 2.3e-50 171.8 4.1 3.2e-49 168.0 2.7 2.0 2 0 0 2 2 2 2 Lipoxygenase HET PF06985.11 EGO61407.1 - 1.6e-28 99.9 0.0 1.6e-28 99.9 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_transf_24 PF18404.1 EGO61407.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Glucosyltransferase 24 NAD_binding_9 PF13454.6 EGO61407.1 - 1.2 9.2 3.5 2.3 8.2 3.5 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF1282 PF06930.12 EGO61408.1 - 0.0029 17.4 0.8 0.0047 16.7 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Cation_efflux PF01545.21 EGO61408.1 - 0.0031 17.3 0.0 0.0047 16.7 0.0 1.2 1 0 0 1 1 1 1 Cation efflux family Neur_chan_memb PF02932.16 EGO61408.1 - 0.042 13.9 0.2 0.14 12.2 0.0 1.9 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 EGO61408.1 - 0.45 8.8 14.2 0.71 8.1 14.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_35 PF01301.19 EGO61409.1 - 4.3e-107 358.4 0.2 6.7e-107 357.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EGO61409.1 - 5.8e-53 178.3 9.9 2.2e-29 102.4 0.1 3.3 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 EGO61409.1 - 1.1e-51 175.2 1.9 2.6e-51 174.0 1.9 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 EGO61409.1 - 1.4e-25 88.6 1.2 3e-25 87.6 1.2 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 EGO61409.1 - 0.00036 20.0 0.0 0.00069 19.1 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Methyltransf_12 PF08242.12 EGO61410.1 - 0.00059 20.5 0.0 0.0014 19.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO61410.1 - 0.00074 20.2 0.0 0.0017 19.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO61410.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO61410.1 - 0.0018 18.9 0.0 0.0044 17.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Xan_ur_permease PF00860.20 EGO61411.1 - 6.5e-25 87.6 23.5 2.2e-24 85.9 22.2 2.1 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 EGO61411.1 - 0.043 14.2 15.5 0.66 10.4 5.0 2.9 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily Dicty_CAR PF05462.11 EGO61412.1 - 4.4e-10 39.2 6.4 4.4e-10 39.2 6.4 1.7 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 EGO61412.1 - 2.7e-08 33.8 4.8 5e-08 33.0 4.8 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 EGO61412.1 - 1.6e-05 24.3 2.3 2.3e-05 23.9 2.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-LITAF-like PF10601.9 EGO61412.1 - 0.036 14.3 0.1 0.036 14.3 0.1 2.9 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain zf-C2H2 PF00096.26 EGO61414.1 - 5.8e-06 26.5 54.3 0.0019 18.6 5.4 7.9 7 1 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGO61414.1 - 0.0052 17.5 10.0 0.024 15.5 3.3 9.2 9 0 0 9 9 9 4 C2H2-type zinc finger zf-MYST PF17772.1 EGO61414.1 - 2.2 7.9 8.3 0.14 11.8 1.0 2.6 2 0 0 2 2 2 0 MYST family zinc finger domain FOXP-CC PF16159.5 EGO61414.1 - 3.4 8.4 21.1 3.5 8.3 0.2 5.1 3 2 1 4 4 4 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 EGO61414.1 - 5.9 7.3 42.6 0.57 10.5 3.9 6.7 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding Sina PF03145.16 EGO61417.1 - 0.033 14.1 4.1 0.073 13.0 4.1 1.5 1 0 0 1 1 1 0 Seven in absentia protein family zf-C2H2_3rep PF18868.1 EGO61417.1 - 0.061 14.0 0.6 1.9 9.1 0.1 3.1 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 EGO61417.1 - 0.088 13.3 7.2 21 5.8 0.1 4.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EGO61417.1 - 0.094 12.9 0.0 5.8 7.0 0.1 2.5 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 EGO61417.1 - 6.2 8.0 14.6 1.7 9.7 0.3 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-rbx1 PF12678.7 EGO61422.1 - 1.9e-09 37.6 4.8 4e-09 36.6 4.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGO61422.1 - 2.1e-09 37.6 5.7 4e-09 36.7 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGO61422.1 - 3.7e-06 26.8 2.1 9.7e-06 25.5 2.2 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGO61422.1 - 6.9e-06 25.8 3.4 1.4e-05 24.8 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGO61422.1 - 9e-06 25.6 2.2 1.8e-05 24.6 2.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGO61422.1 - 3.5e-05 23.6 7.6 0.00054 19.8 8.0 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGO61422.1 - 0.00011 22.0 3.4 0.00027 20.7 3.4 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGO61422.1 - 0.00015 21.8 1.3 0.00033 20.7 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGO61422.1 - 0.00025 20.6 0.5 0.00054 19.5 0.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EGO61422.1 - 0.00052 19.8 6.8 0.0015 18.4 6.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-FPG_IleRS PF06827.14 EGO61422.1 - 0.072 13.0 0.8 0.22 11.4 0.8 1.9 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-RING_11 PF17123.5 EGO61422.1 - 0.11 12.3 1.2 0.7 9.7 1.2 2.2 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 EGO61422.1 - 0.9 9.8 3.7 4.2 7.6 3.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 EGO61422.1 - 1.1 9.2 4.1 3.2 7.6 4.3 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain SOG2 PF10428.9 EGO61422.1 - 4.1 6.5 13.7 8.2 5.5 13.7 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein RINGv PF12906.7 EGO61422.1 - 5.7 7.1 5.5 16 5.7 5.5 1.8 1 1 0 1 1 1 0 RING-variant domain NmrA PF05368.13 EGO61424.1 - 2e-05 24.3 0.0 0.0015 18.2 0.0 2.5 3 0 0 3 3 3 2 NmrA-like family NAD_binding_10 PF13460.6 EGO61424.1 - 9.6e-05 22.4 0.0 0.0014 18.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EGO61424.1 - 0.024 14.9 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CsbD PF05532.12 EGO61425.1 - 5.7e-18 64.6 27.5 2.9e-08 33.5 7.9 3.3 2 1 1 3 3 3 3 CsbD-like Aminotran_5 PF00266.19 EGO61426.1 - 4e-94 315.6 0.0 5.3e-94 315.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGO61426.1 - 4.7e-07 29.4 0.0 4.7e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGO61426.1 - 1.9e-06 27.5 0.4 7.1e-06 25.6 0.1 2.0 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 EGO61426.1 - 0.005 15.6 0.0 0.0082 14.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain BAR PF03114.18 EGO61427.1 - 1.1e-72 244.5 8.8 1.5e-72 244.1 8.8 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EGO61427.1 - 1.6e-14 53.2 0.0 3.6e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGO61427.1 - 3.8e-09 36.3 0.0 7e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGO61427.1 - 3.5e-07 29.8 0.1 1.6e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Sec20 PF03908.13 EGO61427.1 - 0.12 12.3 0.8 7.5 6.5 0.1 2.4 2 0 0 2 2 2 0 Sec20 Vps5 PF09325.10 EGO61427.1 - 0.69 9.4 7.6 1.8 8.1 3.8 2.2 2 0 0 2 2 2 0 Vps5 C terminal like Radial_spoke_3 PF06098.11 EGO61427.1 - 2.8 7.1 10.3 0.63 9.3 3.2 2.1 2 0 0 2 2 2 0 Radial spoke protein 3 TMPIT PF07851.13 EGO61427.1 - 2.8 7.1 7.9 4.9 6.3 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein PrmC_N PF17827.1 EGO61428.1 - 0.18 12.4 1.1 23 5.7 0.1 2.5 2 0 0 2 2 2 0 PrmC N-terminal domain MARVEL PF01284.23 EGO61429.1 - 3.7e-26 91.9 14.2 4.3e-26 91.7 14.2 1.0 1 0 0 1 1 1 1 Membrane-associating domain eIF-5_eIF-2B PF01873.17 EGO61431.1 - 6.3e-41 138.9 0.2 1.1e-40 138.1 0.2 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zinc_ribbon_6 PF14599.6 EGO61431.1 - 0.091 12.8 0.5 12 6.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon Arc_trans_TRASH PF08394.10 EGO61431.1 - 1.7 9.1 7.2 1.5 9.2 0.2 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain PKI PF02827.16 EGO61431.1 - 6.2 7.1 9.4 0.78 10.0 3.5 2.4 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor DAO PF01266.24 EGO61432.1 - 3.4e-37 128.9 8.4 1.1e-36 127.2 8.4 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGO61432.1 - 0.055 13.7 2.5 0.099 12.9 1.9 1.8 1 1 1 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGO61432.1 - 0.16 12.0 0.1 27 4.7 0.3 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EGO61432.1 - 0.21 10.8 0.0 0.47 9.6 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MtrD PF04207.12 EGO61432.1 - 0.68 9.6 2.5 3.3 7.4 0.5 2.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D A_deaminase PF00962.22 EGO61433.1 - 1e-26 94.0 0.0 1.7e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase YgbB PF02542.16 EGO61433.1 - 0.17 12.1 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 YgbB family PNGaseA PF12222.8 EGO61434.1 - 1.7e-181 603.9 5.7 2.5e-181 603.3 5.7 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1279 PF06916.13 EGO61435.1 - 3.9e-26 91.4 0.5 1e-25 90.1 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) AIM24 PF01987.17 EGO61436.1 - 1.1e-50 172.3 0.1 1.3e-50 172.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 GHMP_kinases_N PF00288.26 EGO61436.1 - 0.038 14.2 0.3 0.073 13.3 0.3 1.4 1 0 0 1 1 1 0 GHMP kinases N terminal domain DNA_primase_lrg PF04104.14 EGO61437.1 - 4.6e-84 282.0 0.0 7.2e-84 281.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Methyltransf_12 PF08242.12 EGO61438.1 - 1.7e-15 57.5 0.1 7.9e-15 55.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO61438.1 - 2.5e-14 53.7 0.0 6e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGO61438.1 - 8.1e-11 42.4 0.0 2.1e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO61438.1 - 4.5e-10 39.6 1.5 6.8e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGO61438.1 - 5.9e-09 35.9 0.0 1.6e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGO61438.1 - 7.1e-08 32.1 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Roc PF08477.13 EGO61438.1 - 0.00058 20.1 0.8 0.21 11.8 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MTS PF05175.14 EGO61438.1 - 0.0046 16.5 0.0 0.0096 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 EGO61438.1 - 0.0064 17.5 0.0 0.02 15.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGO61438.1 - 0.0071 16.3 0.6 0.074 13.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGO61438.1 - 0.014 15.3 0.0 0.053 13.4 0.0 1.9 1 1 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_16 PF10294.9 EGO61438.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DUF3298 PF11738.8 EGO61438.1 - 0.78 10.8 0.0 0.78 10.8 0.0 3.1 2 1 0 2 2 1 0 Protein of unknown function (DUF3298) CN_hydrolase PF00795.22 EGO61439.1 - 2.1e-42 145.2 0.0 3e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EGO61439.1 - 5.2e-21 74.9 0.0 1.5e-20 73.4 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Polyketide_cyc PF03364.20 EGO61440.1 - 7.9e-39 132.8 0.0 1.1e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Se-cys_synth_N PF12390.8 EGO61441.1 - 0.038 14.2 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 Selenocysteine synthase N terminal TPR_11 PF13414.6 EGO61443.1 - 7.5e-14 51.1 0.3 2.3e-06 27.2 0.2 3.7 2 1 1 3 3 3 3 TPR repeat TPR_19 PF14559.6 EGO61443.1 - 1.5e-09 38.2 5.1 4.5e-06 27.1 0.3 4.7 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGO61443.1 - 5.1e-09 36.2 13.2 0.00091 19.9 0.2 5.9 3 1 3 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGO61443.1 - 1.4e-07 31.1 14.1 3.7e-06 26.6 0.2 5.2 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGO61443.1 - 6.9e-06 25.9 2.7 0.0023 18.0 0.3 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGO61443.1 - 5e-05 22.9 0.7 0.00059 19.6 0.1 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGO61443.1 - 0.00013 22.1 0.0 0.12 12.9 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGO61443.1 - 0.00043 20.9 0.3 0.00043 20.9 0.3 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGO61443.1 - 0.0013 18.8 0.4 0.0013 18.8 0.4 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO61443.1 - 0.0027 18.0 16.0 0.012 15.9 0.4 4.6 3 1 2 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGO61443.1 - 0.0041 17.1 4.1 2.5 8.3 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.10 EGO61443.1 - 0.016 14.3 0.1 0.021 13.8 0.1 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 EGO61443.1 - 0.024 14.9 2.4 0.25 11.7 0.0 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO61443.1 - 0.03 15.0 1.6 12 6.8 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat FAT PF02259.23 EGO61443.1 - 0.049 12.8 0.1 6 6.0 0.0 2.4 1 1 1 2 2 2 0 FAT domain Pro-MCH PF05824.12 EGO61443.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) Vps39_1 PF10366.9 EGO61443.1 - 0.075 13.3 0.3 13 6.1 0.0 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Adaptin_N PF01602.20 EGO61444.1 - 1.1e-87 294.8 0.7 1.5e-87 294.4 0.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Tau95_N PF17682.1 EGO61444.1 - 0.039 14.1 2.1 2.6 8.2 1.4 2.8 2 0 0 2 2 2 0 Tau95 Triple barrel domain V-ATPase_H_C PF11698.8 EGO61444.1 - 0.058 13.5 0.3 5 7.3 0.0 3.7 2 1 0 3 3 3 0 V-ATPase subunit H HEAT_2 PF13646.6 EGO61444.1 - 1.7 9.1 4.8 1 9.8 0.1 3.1 3 1 0 3 3 3 0 HEAT repeats LCCL PF03815.19 EGO61445.1 - 4.3e-19 68.4 0.1 7.9e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 LCCL domain PKD_3 PF16820.5 EGO61445.1 - 0.15 11.8 0.1 0.43 10.4 0.1 1.7 1 0 0 1 1 1 0 PKD-like domain TGT PF01702.18 EGO61446.1 - 8.8e-67 225.7 0.0 1.1e-66 225.4 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase TipAS PF07739.13 EGO61446.1 - 0.049 14.2 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Abhydrolase_2 PF02230.16 EGO61447.1 - 7.1e-13 48.9 0.0 2.1e-07 31.0 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 EGO61447.1 - 0.0065 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 EGO61447.1 - 0.14 11.7 0.2 0.34 10.4 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family MFS_1 PF07690.16 EGO61448.1 - 4.7e-32 111.3 33.5 4.7e-32 111.3 33.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Neurensin PF14927.6 EGO61448.1 - 0.052 13.3 0.1 9.6 5.9 0.0 3.1 3 0 0 3 3 3 0 Neurensin DUF3522 PF12036.8 EGO61448.1 - 0.62 10.3 11.8 5.8 7.2 1.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3522) UNC-93 PF05978.16 EGO61448.1 - 0.72 9.6 8.8 0.11 12.1 2.0 2.3 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 PALP PF00291.25 EGO61449.1 - 6.4e-45 153.8 0.1 7.8e-45 153.5 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme APG5 PF04106.12 EGO61451.1 - 7.6e-27 94.4 0.0 2.1e-25 89.6 0.0 2.3 1 1 1 2 2 2 2 Autophagy protein Apg5 Zn_clus PF00172.18 EGO61452.1 - 1.8e-06 28.0 13.4 2.7e-06 27.4 13.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3919 PF13057.6 EGO61452.1 - 0.059 13.0 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) WD40 PF00400.32 EGO61458.1 - 1.8e-06 28.6 8.0 0.13 13.2 0.1 4.2 5 0 0 5 5 5 3 WD domain, G-beta repeat PhzC-PhzF PF02567.16 EGO61460.1 - 1.4e-21 77.2 0.0 1.8e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Peptidase_S8 PF00082.22 EGO61462.1 - 1.6e-08 34.2 0.1 2.3e-07 30.4 0.1 2.4 1 1 0 1 1 1 1 Subtilase family EST1 PF10374.9 EGO61462.1 - 0.15 12.7 0.4 0.65 10.6 0.0 2.3 2 0 0 2 2 2 0 Telomerase activating protein Est1 Pkinase_fungal PF17667.1 EGO61465.1 - 1.2e-135 452.4 0.0 1.5e-135 452.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGO61465.1 - 0.00061 19.2 0.0 0.00099 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGO61465.1 - 0.0058 16.6 0.2 0.025 14.5 0.2 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family MauJ PF17419.2 EGO61465.1 - 0.036 13.5 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Methylamine utilization protein MauJ Profilin PF00235.19 EGO61466.1 - 4.9e-40 136.7 0.2 5.4e-40 136.6 0.2 1.0 1 0 0 1 1 1 1 Profilin MAPEG PF01124.18 EGO61467.1 - 1.9e-24 86.0 0.6 2.1e-24 85.9 0.6 1.0 1 0 0 1 1 1 1 MAPEG family MARVEL PF01284.23 EGO61469.1 - 2.5e-19 69.7 13.4 3e-19 69.5 13.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2976 PF11190.8 EGO61469.1 - 0.07 12.9 0.4 0.07 12.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) PRA1 PF03208.19 EGO61469.1 - 10 5.8 10.5 3.2 7.4 6.8 1.8 2 0 0 2 2 2 0 PRA1 family protein DUF4449 PF14613.6 EGO61470.1 - 8.8e-06 25.9 6.5 1.8e-05 24.9 0.1 3.8 4 1 1 5 5 5 1 Protein of unknown function (DUF4449) LBP_BPI_CETP PF01273.25 EGO61470.1 - 0.002 17.8 0.0 0.0045 16.6 0.0 1.6 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain AbiH PF14253.6 EGO61470.1 - 0.011 15.6 2.3 0.018 14.9 1.3 1.8 1 1 1 2 2 2 0 Bacteriophage abortive infection AbiH Tricorn_C1 PF14684.6 EGO61470.1 - 0.065 13.3 0.8 0.63 10.2 0.1 3.0 4 0 0 4 4 4 0 Tricorn protease C1 domain Patatin PF01734.22 EGO61471.1 - 1.5e-16 61.2 0.0 2.7e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Fungal_trans_2 PF11951.8 EGO61473.1 - 1.4e-07 30.6 0.0 2.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C14 PF00656.22 EGO61474.1 - 0.00036 20.6 0.0 0.00087 19.3 0.0 1.7 1 0 0 1 1 1 1 Caspase domain zf-TRAF PF02176.18 EGO61474.1 - 0.059 14.1 1.4 0.24 12.1 1.4 2.2 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.8 EGO61474.1 - 0.11 12.9 4.2 9.5 6.6 0.4 3.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Raptor_N PF14538.6 EGO61474.1 - 0.14 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain zf-C2H2_4 PF13894.6 EGO61474.1 - 0.26 12.2 20.6 0.11 13.4 2.2 4.7 4 1 0 4 4 4 0 C2H2-type zinc finger DUF5327 PF17261.2 EGO61474.1 - 0.34 11.7 0.1 0.34 11.7 0.1 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5327) Sina PF03145.16 EGO61474.1 - 0.37 10.7 4.6 0.37 10.7 2.7 2.0 2 0 0 2 2 2 0 Seven in absentia protein family zf-C2H2 PF00096.26 EGO61474.1 - 1.6 9.3 24.2 0.1 13.1 2.1 4.7 5 1 0 5 5 5 0 Zinc finger, C2H2 type Glyco_hydro_31 PF01055.26 EGO61475.1 - 5.5e-157 523.5 1.5 8.8e-157 522.8 1.3 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EGO61475.1 - 5e-41 139.5 0.0 8.8e-41 138.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EGO61475.1 - 3.9e-14 52.7 1.8 2.6e-13 50.1 1.6 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like GST_C_3 PF14497.6 EGO61478.1 - 1e-29 102.7 0.1 1.7e-29 101.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGO61478.1 - 8.5e-05 22.7 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGO61478.1 - 0.0087 16.1 0.0 0.019 15.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGO61478.1 - 0.02 15.5 0.1 0.057 14.0 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGO61478.1 - 0.15 12.4 0.1 2.4 8.6 0.1 2.5 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF2183 PF09949.9 EGO61479.1 - 1.2e-33 115.4 0.0 2.7e-33 114.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Spore_YunB PF09560.10 EGO61481.1 - 0.017 15.2 0.3 0.019 15.0 0.3 1.1 1 0 0 1 1 1 0 Sporulation protein YunB (Spo_YunB) Amidohydro_1 PF01979.20 EGO61490.1 - 5e-42 144.4 0.0 7.7e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family An_peroxidase PF03098.15 EGO61490.1 - 2.4e-33 115.5 0.6 3.1e-22 78.9 1.0 4.9 1 1 1 2 2 2 2 Animal haem peroxidase Amidohydro_3 PF07969.11 EGO61490.1 - 8.5e-15 55.2 0.3 2.7e-09 37.0 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family Retrotrans_gag PF03732.17 EGO61491.1 - 0.011 16.0 0.1 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein Glyco_hydro_16 PF00722.21 EGO61492.1 - 1.5e-41 141.8 0.6 2.9e-41 140.9 0.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.6 EGO61492.1 - 0.048 13.8 3.2 0.074 13.2 1.5 2.1 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily Adap_comp_sub PF00928.21 EGO61493.1 - 5e-86 288.3 0.0 6.4e-86 288.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGO61493.1 - 5.3e-05 23.2 0.2 9.7e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RIBIOP_C PF04950.12 EGO61493.1 - 0.037 13.4 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Methyltransf_3 PF01596.17 EGO61494.1 - 2.2e-29 102.1 0.0 2.9e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EGO61494.1 - 2.8e-11 44.4 0.0 4.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGO61494.1 - 1.6e-06 28.1 0.0 2.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TrmK PF04816.12 EGO61494.1 - 7.9e-05 22.3 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_31 PF13847.6 EGO61494.1 - 0.0006 19.6 0.0 0.0009 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGO61494.1 - 0.001 19.7 0.0 0.0021 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGO61494.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 EGO61494.1 - 0.0038 16.8 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 EGO61494.1 - 0.0042 16.8 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CmcI PF04989.12 EGO61494.1 - 0.0058 16.4 0.0 0.0086 15.8 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase PCMT PF01135.19 EGO61494.1 - 0.018 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 EGO61494.1 - 0.043 14.5 0.0 0.077 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EGO61494.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.17 EGO61494.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Cluap1 PF10234.9 EGO61495.1 - 0.059 12.8 0.7 0.11 11.9 0.7 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 Bestrophin PF01062.21 EGO61496.1 - 1e-30 107.2 0.1 1.7e-30 106.4 0.1 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PHO4 PF01384.20 EGO61496.1 - 0.07 12.2 1.4 0.3 10.1 1.4 2.0 1 1 0 1 1 1 0 Phosphate transporter family MFS_1 PF07690.16 EGO61497.1 - 5.2e-32 111.1 31.9 5.2e-32 111.1 31.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Wzy_C PF04932.15 EGO61497.1 - 0.024 14.3 0.8 0.024 14.3 0.8 3.0 2 1 1 3 3 3 0 O-Antigen ligase PLDc_2 PF13091.6 EGO61498.1 - 1.5e-21 76.7 0.0 5e-15 55.6 0.0 3.1 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 EGO61498.1 - 6.5e-05 23.0 0.0 0.079 13.2 0.0 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 EGO61498.1 - 0.16 11.1 0.1 2.3 7.4 0.0 2.7 4 0 0 4 4 4 0 Archaeal transcriptional regulator TrmB Glyco_hydro_6 PF01341.17 EGO61500.1 - 2.9e-107 358.9 0.4 3.9e-107 358.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 EGO61500.1 - 9.7e-11 41.4 11.4 2.7e-10 40.0 11.4 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Yeast-kill-tox PF09207.11 EGO61500.1 - 0.042 14.5 7.7 0.15 12.7 5.4 2.6 2 0 0 2 2 2 0 Yeast killer toxin MGC-24 PF05283.11 EGO61500.1 - 3.9 7.9 18.0 0.71 10.3 13.0 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MAGE_N PF12440.8 EGO61500.1 - 6 7.6 13.0 18 6.1 13.0 1.7 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal ThuA PF06283.11 EGO61502.1 - 3.5e-50 171.1 0.1 3.1e-48 164.8 0.1 2.0 1 1 0 1 1 1 1 Trehalose utilisation Hydrolase_like PF13242.6 EGO61503.1 - 0.0027 17.7 0.0 0.0063 16.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Tex_N PF09371.10 EGO61503.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Tex-like protein N-terminal domain PBP1_TM PF14812.6 EGO61504.1 - 1.2 9.6 3.5 1.7 9.1 3.5 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1772 PF08592.11 EGO61505.1 - 1.7e-20 73.7 0.0 2.1e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Inp1 PF12634.7 EGO61505.1 - 0.0039 17.2 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 STE3 PF02076.15 EGO61505.1 - 0.02 14.1 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Pheromone A receptor Gaa1 PF04114.14 EGO61505.1 - 0.045 12.8 0.0 0.051 12.6 0.0 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component Opi1 PF08618.10 EGO61506.1 - 6.7e-18 65.1 8.3 1.1e-15 57.9 3.7 3.0 1 1 1 3 3 3 3 Transcription factor Opi1 DASH_Dad2 PF08654.10 EGO61506.1 - 0.2 12.1 2.7 9.2 6.8 0.1 3.1 2 1 0 3 3 3 0 DASH complex subunit Dad2 Adap_comp_sub PF00928.21 EGO61509.1 - 2.3e-91 305.8 0.0 4.1e-91 305.0 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGO61509.1 - 5.8e-09 36.0 0.2 9.6e-09 35.3 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Prion PF00377.18 EGO61510.1 - 0.02 14.7 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain Abhydrolase_3 PF07859.13 EGO61511.1 - 4.4e-17 62.6 0.0 1.8e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGO61511.1 - 3e-09 36.7 0.0 2.4e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 EGO61511.1 - 0.00045 19.2 0.0 0.001 18.0 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 EGO61511.1 - 0.0016 17.7 0.0 0.24 10.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGO61512.1 - 1.2e-13 51.3 0.0 3.2e-13 49.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGO61512.1 - 1.4e-11 45.4 0.0 1.9e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO61512.1 - 7.3e-07 28.7 0.0 4.2e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 EGO61512.1 - 0.0011 18.6 0.0 0.0051 16.4 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Thioesterase PF00975.20 EGO61512.1 - 0.006 16.7 0.0 0.0077 16.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EGO61512.1 - 0.026 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein FSH1 PF03959.13 EGO61512.1 - 0.091 12.4 0.0 0.7 9.5 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 EGO61512.1 - 0.1 12.1 0.1 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PhoPQ_related PF10142.9 EGO61512.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein LIP PF03583.14 EGO61512.1 - 0.15 11.4 0.0 3 7.1 0.0 2.1 1 1 0 1 1 1 0 Secretory lipase Peptidase_S15 PF02129.18 EGO61512.1 - 0.18 11.4 0.0 1.2 8.7 0.0 2.2 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 EGO61512.1 - 0.2 11.8 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF915 PF06028.11 EGO61512.1 - 0.22 10.8 0.0 0.43 9.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PAP2 PF01569.21 EGO61514.1 - 4.3e-27 94.5 1.0 4.3e-27 94.5 1.0 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 EGO61514.1 - 0.28 11.8 6.4 0.059 13.9 1.6 2.4 2 1 0 2 2 2 0 PAP2 superfamily C-terminal DUF983 PF06170.12 EGO61514.1 - 2.8 8.4 6.2 9.6 6.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF983) FAM70 PF14967.6 EGO61515.1 - 7.7 5.9 7.7 1.6 8.1 4.3 1.5 2 0 0 2 2 2 0 FAM70 protein 4HBT_3 PF13622.6 EGO61516.1 - 1.3e-42 146.7 0.0 1.7e-42 146.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF829 PF05705.14 EGO61517.1 - 1.5e-68 231.3 0.1 1.7e-68 231.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) SRP54 PF00448.22 EGO61518.1 - 1.3e-75 253.4 3.3 3.9e-75 251.8 1.4 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EGO61518.1 - 1.3e-31 109.1 5.9 1.3e-31 109.1 5.9 3.3 2 1 0 3 3 1 1 Signal peptide binding domain SRP54_N PF02881.19 EGO61518.1 - 6.8e-21 74.3 0.2 1.9e-20 72.8 0.2 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EGO61518.1 - 1.1e-06 28.3 1.5 8.5e-06 25.5 1.2 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 EGO61518.1 - 1.9e-05 25.1 1.3 4.1e-05 24.0 0.2 2.2 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 EGO61518.1 - 5.9e-05 23.2 0.1 0.00019 21.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain MeaB PF03308.16 EGO61518.1 - 0.00038 19.5 4.3 0.00057 18.9 1.7 2.5 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 EGO61518.1 - 0.00071 19.5 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 EGO61518.1 - 0.00075 19.3 0.1 0.003 17.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 EGO61518.1 - 0.00079 19.5 0.0 0.0023 18.0 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EGO61518.1 - 0.0011 19.4 0.0 0.0023 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 EGO61518.1 - 0.0021 18.0 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Thymidylate_kin PF02223.17 EGO61518.1 - 0.0025 17.5 0.2 0.032 13.9 0.0 2.4 2 0 0 2 2 2 1 Thymidylate kinase AAA_18 PF13238.6 EGO61518.1 - 0.0026 18.3 0.0 0.0065 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EGO61518.1 - 0.004 17.2 0.6 0.051 13.7 0.2 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EGO61518.1 - 0.0041 16.9 0.2 0.017 14.9 0.1 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 EGO61518.1 - 0.0042 16.4 0.0 0.0093 15.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 EGO61518.1 - 0.0078 16.6 0.2 0.035 14.5 0.1 2.3 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 EGO61518.1 - 0.0086 15.5 1.6 4.1 6.8 1.2 3.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EGO61518.1 - 0.015 15.6 0.0 0.042 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGO61518.1 - 0.021 15.1 0.1 0.041 14.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain VirC1 PF07015.11 EGO61518.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein NTPase_1 PF03266.15 EGO61518.1 - 0.029 14.3 0.5 0.083 12.8 0.0 1.9 2 0 0 2 2 2 0 NTPase ResIII PF04851.15 EGO61518.1 - 0.044 13.8 0.2 0.12 12.4 0.2 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Arf PF00025.21 EGO61518.1 - 0.053 13.0 0.1 0.27 10.7 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family 6PF2K PF01591.18 EGO61518.1 - 0.07 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ABC_tran PF00005.27 EGO61518.1 - 0.08 13.5 0.1 0.34 11.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_31 PF13614.6 EGO61518.1 - 0.082 12.8 0.0 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain SKA2 PF16740.5 EGO61518.1 - 0.12 12.1 3.7 8.6 6.2 0.0 2.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF3052 PF11253.8 EGO61518.1 - 0.14 12.1 0.1 0.38 10.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) MFS_1 PF07690.16 EGO61520.1 - 7.7e-34 117.2 25.9 7.7e-34 117.2 25.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MMPL PF03176.15 EGO61520.1 - 0.12 11.3 0.3 2.1 7.2 0.1 2.2 2 0 0 2 2 2 0 MMPL family LapA_dom PF06305.11 EGO61520.1 - 0.48 10.3 5.6 4.1 7.3 0.0 4.0 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Phage_holin_3_6 PF07332.11 EGO61520.1 - 9.1 6.4 8.9 6.7 6.8 0.2 3.5 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Peptidase_M20 PF01546.28 EGO61522.1 - 9.6e-11 41.8 0.1 1.4e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGO61522.1 - 8.3e-06 25.7 0.0 2.5e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.16 EGO61523.1 - 4.2e-22 78.5 14.0 4.2e-22 78.5 14.0 4.3 3 1 1 4 4 4 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO61523.1 - 2.8e-09 36.4 2.0 2.8e-09 36.4 2.0 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter FA_desaturase PF00487.24 EGO61523.1 - 0.12 12.2 0.0 0.12 12.2 0.0 4.9 5 0 0 5 5 5 0 Fatty acid desaturase Hap4_Hap_bind PF10297.9 EGO61527.1 - 2.1e-07 30.8 6.7 4.2e-07 29.9 6.7 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 EGO61527.1 - 1.7e-06 28.0 11.4 8.4e-05 22.6 8.2 2.7 1 1 1 2 2 2 2 bZIP transcription factor SPATA24 PF15175.6 EGO61527.1 - 0.027 14.4 1.6 0.042 13.8 1.6 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 EzrA PF06160.12 EGO61527.1 - 0.033 12.4 0.7 0.043 12.0 0.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA HMMR_N PF15905.5 EGO61527.1 - 0.045 13.2 8.0 0.063 12.7 8.0 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Jnk-SapK_ap_N PF09744.9 EGO61527.1 - 0.054 13.7 8.8 0.1 12.8 8.8 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 dsrm PF00035.26 EGO61527.1 - 0.063 14.0 0.0 0.22 12.2 0.0 1.9 1 0 0 1 1 1 0 Double-stranded RNA binding motif Exonuc_VII_L PF02601.15 EGO61527.1 - 0.079 12.5 4.6 0.12 12.0 4.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 EGO61527.1 - 0.17 12.0 1.0 0.3 11.1 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MPS2 PF17060.5 EGO61527.1 - 0.18 11.0 2.2 0.24 10.6 2.2 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 TEX13 PF15186.6 EGO61527.1 - 0.2 11.3 8.1 0.39 10.4 8.1 1.5 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family CLZ PF16526.5 EGO61527.1 - 0.23 11.8 3.0 0.63 10.4 3.0 1.7 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_2 PF07716.15 EGO61527.1 - 0.47 10.6 12.8 0.61 10.2 9.9 2.4 1 1 1 2 2 2 0 Basic region leucine zipper DUF1043 PF06295.12 EGO61527.1 - 0.54 10.3 4.7 1 9.4 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Fmp27_WPPW PF10359.9 EGO61527.1 - 0.8 8.5 6.7 1.1 8.0 6.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PAT1 PF09770.9 EGO61527.1 - 5 5.3 11.4 7.2 4.7 11.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 bZIP_Maf PF03131.17 EGO61527.1 - 6.5 7.4 17.0 0.61 10.6 7.0 2.7 1 1 1 2 2 2 0 bZIP Maf transcription factor ATF7IP_BD PF16788.5 EGO61527.1 - 6.9 6.7 9.9 0.24 11.5 3.5 1.7 2 0 0 2 2 2 0 ATF-interacting protein binding domain COG2 PF06148.11 EGO61528.1 - 6e-18 65.2 0.0 7.8e-17 61.6 0.0 2.4 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EGO61528.1 - 0.034 14.2 0.0 0.1 12.7 0.0 2.0 1 0 0 1 1 1 0 Vps51/Vps67 COG5 PF10392.9 EGO61528.1 - 0.093 12.9 0.0 0.2 11.8 0.0 1.6 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Ribosomal_L1 PF00687.21 EGO61529.1 - 1e-23 84.2 0.1 1.3e-23 83.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.21 EGO61530.1 - 2.7e-106 355.0 1.0 2.3e-105 351.9 0.1 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGO61530.1 - 1.8e-39 135.4 0.2 3.6e-39 134.4 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 EGO61530.1 - 0.0028 17.0 0.3 0.0077 15.6 0.3 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Choline_transpo PF04515.12 EGO61531.1 - 3.5e-81 272.9 21.2 3.5e-81 272.9 21.2 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF4064 PF13273.6 EGO61531.1 - 0.0015 18.8 3.7 0.0015 18.8 3.7 4.4 4 1 2 6 6 6 2 Protein of unknown function (DUF4064) DUF4267 PF14087.6 EGO61531.1 - 0.36 10.9 6.6 0.33 11.0 3.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4267) IPPT PF01715.17 EGO61533.1 - 8.6e-61 205.7 0.2 8.6e-61 205.7 0.2 1.5 2 0 0 2 2 2 1 IPP transferase zf-C2H2_jaz PF12171.8 EGO61533.1 - 4.6e-06 26.8 6.3 9.4e-06 25.8 6.3 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding IPT PF01745.16 EGO61533.1 - 3.6e-05 23.3 0.0 0.00011 21.7 0.0 1.7 2 0 0 2 2 2 1 Isopentenyl transferase zf-met PF12874.7 EGO61533.1 - 4.5e-05 23.7 1.4 4.5e-05 23.7 1.4 1.7 1 1 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGO61533.1 - 0.00024 21.4 0.6 0.00044 20.5 0.6 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Cytidylate_kin PF02224.18 EGO61533.1 - 0.0021 17.8 0.0 0.023 14.4 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase AAA_33 PF13671.6 EGO61533.1 - 0.0024 18.0 0.4 0.05 13.8 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EGO61533.1 - 0.0055 17.3 1.1 0.73 10.4 0.0 3.0 3 1 1 4 4 3 1 AAA domain AAA_28 PF13521.6 EGO61533.1 - 0.0088 16.3 0.3 0.39 10.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain zf-DBF PF07535.12 EGO61533.1 - 0.011 15.9 1.4 0.023 14.8 1.4 1.5 1 0 0 1 1 1 0 DBF zinc finger RNA_helicase PF00910.22 EGO61533.1 - 0.018 15.4 0.0 0.056 13.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EGO61533.1 - 0.04 14.3 1.4 0.097 13.0 0.0 2.4 2 2 0 2 2 2 0 AAA ATPase domain HDPD PF02924.14 EGO61533.1 - 0.061 13.4 0.0 0.4 10.8 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage lambda head decoration protein D Hpr_kinase_C PF07475.12 EGO61533.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 EGO61533.1 - 0.094 13.0 0.0 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGO61533.1 - 0.11 13.0 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PYRIN PF02758.16 EGO61533.1 - 0.11 12.6 0.3 17 5.7 0.0 2.6 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain tRNA-synt_1g PF09334.11 EGO61533.1 - 0.12 11.1 2.1 0.28 9.9 0.4 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (M) zf-C2H2_4 PF13894.6 EGO61533.1 - 0.12 13.3 0.3 0.3 12.0 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGO61533.1 - 0.7 10.5 1.7 1.1 9.8 0.6 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Lsr2 PF11774.8 EGO61533.1 - 6.2 7.0 8.1 2.1 8.5 0.0 3.2 3 0 0 3 3 3 0 Lsr2 SecY PF00344.20 EGO61534.1 - 1.9e-71 240.8 9.2 2.4e-71 240.5 9.2 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EGO61534.1 - 1.2e-17 63.5 0.3 3.2e-17 62.1 0.3 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p DUF2975 PF11188.8 EGO61534.1 - 0.29 11.0 2.8 1.1 9.2 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Aconitase PF00330.20 EGO61535.1 - 2.1e-110 369.9 0.2 1.6e-109 367.0 0.2 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGO61535.1 - 8.9e-24 84.3 0.0 1.7e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Fungal_trans PF04082.18 EGO61536.1 - 3.6e-15 55.7 0.0 9e-14 51.1 0.0 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Matrilin_ccoil PF10393.9 EGO61536.1 - 0.2 11.5 0.5 0.61 10.0 0.5 1.7 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin PilJ PF13675.6 EGO61536.1 - 0.3 11.1 1.6 0.89 9.6 0.2 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Oxidored_FMN PF00724.20 EGO61537.1 - 4.5e-46 157.7 0.0 5.8e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EGO61537.1 - 0.01 14.9 0.0 0.023 13.8 0.0 1.6 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Radical_SAM PF04055.21 EGO61537.1 - 0.14 12.6 0.1 10 6.4 0.0 3.0 2 1 0 3 3 3 0 Radical SAM superfamily Fungal_trans PF04082.18 EGO61538.1 - 2.4e-07 30.1 0.1 2.4e-07 30.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO61538.1 - 3.4e-07 30.3 13.6 8.2e-07 29.0 13.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OATP PF03137.20 EGO61538.1 - 0.0006 18.2 3.0 0.14 10.4 0.1 2.2 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF2722 PF10846.8 EGO61538.1 - 0.0029 16.6 9.1 0.0053 15.8 9.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) UPF0524 PF15823.5 EGO61538.1 - 0.095 12.1 5.6 0.76 9.1 0.4 2.7 2 0 0 2 2 2 0 UPF0524 of C3orf70 CPSF100_C PF13299.6 EGO61538.1 - 0.11 12.6 0.7 0.26 11.5 0.7 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Peptidase_S15 PF02129.18 EGO61538.1 - 0.45 10.1 4.2 0.74 9.4 4.2 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) MMR1 PF08505.10 EGO61538.1 - 0.48 10.7 11.9 0.016 15.5 5.4 1.8 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DUF4834 PF16118.5 EGO61538.1 - 1.8 9.6 5.6 5.1 8.1 5.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AAA_23 PF13476.6 EGO61538.1 - 3.7 8.0 9.4 5.9 7.3 9.4 1.3 1 0 0 1 1 1 0 AAA domain Spt20 PF12090.8 EGO61538.1 - 4.9 6.7 25.6 0.18 11.4 19.1 1.9 2 0 0 2 2 2 0 Spt20 family Suf PF05843.14 EGO61538.1 - 7.6 6.4 9.4 0.14 12.2 2.2 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TERB2 PF15101.6 EGO61538.1 - 7.8 6.5 9.5 15 5.6 9.5 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Fig1 PF12351.8 EGO61539.1 - 2.7e-37 128.5 0.9 3.3e-37 128.2 0.2 1.4 1 1 1 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EGO61539.1 - 5.8e-06 26.1 2.7 1.7e-05 24.5 2.7 1.8 1 1 0 1 1 1 1 SUR7/PalI family ResB PF05140.14 EGO61539.1 - 4.9 5.8 5.7 0.53 9.0 0.0 2.1 2 1 1 3 3 3 0 ResB-like family DUF4064 PF13273.6 EGO61539.1 - 6.1 7.2 10.3 1.2 9.4 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) Peroxidase_2 PF01328.17 EGO61540.1 - 3.3e-51 174.5 0.0 4e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Rad50_zn_hook PF04423.14 EGO61541.1 - 0.018 14.8 0.4 0.049 13.5 0.4 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif Nop10p PF04135.12 EGO61542.1 - 9.2e-18 64.0 0.2 1.8e-17 63.1 0.2 1.5 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DUF3520 PF12034.8 EGO61542.1 - 0.00084 19.5 0.6 0.00098 19.3 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3520) NOB1_Zn_bind PF08772.11 EGO61543.1 - 3.1e-31 107.3 3.9 5.6e-31 106.5 3.9 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 EGO61543.1 - 3.4e-31 107.6 0.5 7e-31 106.6 0.1 1.8 2 0 0 2 2 2 1 PIN domain of ribonuclease HypA PF01155.19 EGO61543.1 - 0.079 13.0 0.5 0.2 11.7 0.5 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 EGO61543.1 - 0.12 12.1 5.4 0.066 12.9 1.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn-ribbon_8 PF09723.10 EGO61543.1 - 2.1 8.5 4.4 4.1 7.6 2.9 2.2 2 0 0 2 2 2 0 Zinc ribbon domain RNA_pol_3_Rpc31 PF11705.8 EGO61543.1 - 6.4 7.0 17.3 14 5.8 17.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SUIM_assoc PF16619.5 EGO61544.1 - 6.7 6.9 11.6 2.7 8.1 4.4 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Dexa_ind PF15198.6 EGO61544.1 - 9.8 6.4 6.6 18 5.5 6.6 1.4 1 0 0 1 1 1 0 Dexamethasone-induced Bys1 PF04681.12 EGO61546.1 - 5.7e-13 49.1 0.6 7e-13 48.8 0.6 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Glyco_hydro_72 PF03198.14 EGO61547.1 - 7.2e-123 409.8 6.4 1.1e-122 409.3 6.4 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EGO61547.1 - 4.2e-23 81.8 5.4 1.7e-22 79.9 5.4 2.1 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 EGO61547.1 - 3.5e-05 23.1 0.3 0.00016 20.9 0.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain LRR_RI_capping PF18779.1 EGO61548.1 - 0.038 13.7 0.1 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 Capping Ribonuclease inhibitor Leucine Rich Repeat Presenilin PF01080.17 EGO61551.1 - 0.0015 17.4 11.7 0.0018 17.1 11.7 1.1 1 0 0 1 1 1 1 Presenilin SDA1 PF05285.12 EGO61551.1 - 0.0033 16.9 28.1 0.0048 16.4 28.1 1.2 1 0 0 1 1 1 1 SDA1 Toxin_17 PF08086.11 EGO61551.1 - 0.012 15.8 0.6 0.028 14.7 0.6 1.6 1 0 0 1 1 1 0 Ergtoxin family BUD22 PF09073.10 EGO61551.1 - 0.075 12.4 39.4 0.12 11.7 39.4 1.3 1 0 0 1 1 1 0 BUD22 SID-1_RNA_chan PF13965.6 EGO61551.1 - 0.1 11.0 4.0 0.15 10.4 4.0 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Utp14 PF04615.13 EGO61551.1 - 0.22 10.1 20.9 0.27 9.8 20.9 1.2 1 0 0 1 1 1 0 Utp14 protein Nop14 PF04147.12 EGO61551.1 - 0.37 8.9 28.6 0.51 8.5 28.6 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.7 EGO61551.1 - 0.5 8.4 18.3 0.62 8.1 18.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 EGO61551.1 - 0.83 8.4 13.4 1.2 7.9 13.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.13 EGO61551.1 - 0.94 8.2 21.0 1.6 7.4 21.0 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 EGO61551.1 - 1 8.3 11.1 1.3 7.9 11.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Mem_trans PF03547.18 EGO61551.1 - 1.3 7.4 6.9 2 6.7 6.9 1.3 1 0 0 1 1 1 0 Membrane transport protein Menin PF05053.13 EGO61551.1 - 1.5 7.1 16.6 2 6.7 16.6 1.2 1 0 0 1 1 1 0 Menin GREB1 PF15782.5 EGO61551.1 - 1.7 5.7 18.3 1.8 5.5 18.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PPP4R2 PF09184.11 EGO61551.1 - 2.3 7.8 23.9 3 7.4 23.9 1.2 1 0 0 1 1 1 0 PPP4R2 Smg8_Smg9 PF10220.9 EGO61551.1 - 3.7 5.7 20.6 4.8 5.4 20.6 1.1 1 0 0 1 1 1 0 Smg8_Smg9 PI3K_1B_p101 PF10486.9 EGO61551.1 - 4.1 5.1 26.4 4.9 4.8 26.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2860 PF11059.8 EGO61553.1 - 0.16 11.2 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2860) Glyco_transf_20 PF00982.21 EGO61554.1 - 0.00034 19.4 1.0 0.0022 16.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 20 DAP PF15228.6 EGO61554.1 - 0.00084 20.5 2.4 0.0021 19.2 2.4 1.6 1 0 0 1 1 1 1 Death-associated protein Ndr PF03096.14 EGO61554.1 - 0.12 11.1 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family Vfa1 PF08432.10 EGO61556.1 - 0.00012 22.4 6.8 0.00015 22.2 6.8 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 U1snRNP70_N PF12220.8 EGO61556.1 - 0.011 16.4 4.0 0.019 15.6 4.0 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Dynactin_p62 PF05502.13 EGO61556.1 - 0.056 12.2 0.8 0.068 11.9 0.8 1.1 1 0 0 1 1 1 0 Dynactin p62 family CPSF100_C PF13299.6 EGO61556.1 - 0.073 13.3 3.6 0.11 12.7 3.6 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Ureide_permease PF07168.11 EGO61556.1 - 0.31 9.8 1.1 0.44 9.2 1.1 1.1 1 0 0 1 1 1 0 Ureide permease BAF1_ABF1 PF04684.13 EGO61556.1 - 0.58 9.1 8.7 0.8 8.7 8.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RR_TM4-6 PF06459.12 EGO61556.1 - 1.1 9.1 7.1 1.4 8.7 7.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med3 PF11593.8 EGO61556.1 - 1.5 7.9 7.7 1.8 7.7 7.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Porph_ging PF09697.10 EGO61556.1 - 2.8 8.6 6.6 5.7 7.6 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) FHIPEP PF00771.20 EGO61556.1 - 3.2 6.1 4.1 2.2 6.6 1.7 1.7 2 0 0 2 2 2 0 FHIPEP family THOC2_N PF16134.5 EGO61556.1 - 6.6 5.2 7.5 8.8 4.8 7.5 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF3222 PF11519.8 EGO61557.1 - 0.11 12.8 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3222) HLH PF00010.26 EGO61559.1 - 0.0066 16.4 0.0 0.0079 16.1 0.0 1.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SNF2_N PF00176.23 EGO61560.1 - 5e-65 219.5 1.1 9.9e-65 218.5 0.7 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 EGO61560.1 - 1.7e-48 164.4 16.0 1.7e-48 164.4 16.0 5.3 4 2 1 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 EGO61560.1 - 6.9e-20 71.5 0.0 1.6e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGO61560.1 - 8.6e-07 29.1 0.0 3.3e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGO61560.1 - 0.00096 18.4 0.1 0.011 14.9 0.0 2.6 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Fe_hyd_lg_C PF02906.14 EGO61560.1 - 0.011 15.5 2.7 0.042 13.5 2.7 2.0 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain ABC_tran PF00005.27 EGO61561.1 - 2.6e-47 160.8 0.0 1.5e-22 80.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EGO61561.1 - 1e-21 76.7 3.6 1e-21 76.7 3.6 2.8 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 EGO61561.1 - 2.9e-17 63.5 5.5 0.00033 20.6 0.0 4.2 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGO61561.1 - 3.2e-12 46.4 0.1 6.7e-05 22.4 0.0 4.5 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGO61561.1 - 3.7e-09 37.4 1.6 0.019 15.5 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EGO61561.1 - 8.7e-09 35.0 0.0 0.0032 17.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGO61561.1 - 2.5e-07 31.2 0.0 0.0044 17.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 EGO61561.1 - 1.1e-06 28.6 0.1 0.035 13.8 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGO61561.1 - 2.9e-06 27.3 0.2 0.012 15.5 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 EGO61561.1 - 4.9e-06 26.9 0.0 0.11 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGO61561.1 - 8.3e-06 25.9 0.0 0.032 14.3 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 EGO61561.1 - 1.8e-05 25.1 0.0 0.0071 16.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGO61561.1 - 4.3e-05 23.5 0.1 0.2 11.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 EGO61561.1 - 5e-05 23.9 0.0 0.083 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EGO61561.1 - 5.2e-05 23.7 0.0 0.7 10.3 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGO61561.1 - 5.4e-05 23.4 0.1 0.53 10.5 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.14 EGO61561.1 - 9.6e-05 22.4 0.1 0.48 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGO61561.1 - 0.00027 21.3 0.6 1.7 9.1 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA_27 PF13514.6 EGO61561.1 - 0.00072 19.2 0.0 0.19 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EGO61561.1 - 0.00078 18.7 0.0 1.8 7.7 0.0 3.3 2 1 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.6 EGO61561.1 - 0.00081 19.4 0.0 2.2 8.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EGO61561.1 - 0.0014 18.4 1.0 1.8 8.2 0.0 3.6 4 0 0 4 4 4 1 AAA domain DUF2813 PF11398.8 EGO61561.1 - 0.0017 17.7 0.3 0.77 9.0 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) Roc PF08477.13 EGO61561.1 - 0.0041 17.3 0.0 3.4 7.9 0.1 3.0 2 1 1 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 EGO61561.1 - 0.0048 16.5 0.0 1.1 8.8 0.0 3.2 3 1 1 4 4 3 1 AAA domain AAA_7 PF12775.7 EGO61561.1 - 0.023 14.2 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 EGO61561.1 - 0.04 13.8 0.3 5.4 6.9 0.0 2.6 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 EGO61561.1 - 0.044 14.2 0.1 14 6.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EGO61561.1 - 0.045 13.7 0.1 3.4 7.5 0.1 2.5 2 0 0 2 2 2 0 NTPase ABC_ATPase PF09818.9 EGO61561.1 - 0.053 12.3 0.3 14 4.3 0.0 3.3 3 1 0 3 3 3 0 Predicted ATPase of the ABC class DUF815 PF05673.13 EGO61561.1 - 0.059 12.5 0.1 2.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FeoB_N PF02421.18 EGO61561.1 - 0.062 12.8 0.3 14 5.1 0.0 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B Dynamin_N PF00350.23 EGO61561.1 - 0.065 13.3 1.6 33 4.5 0.0 3.9 4 1 0 5 5 4 0 Dynamin family Phage_tail_2 PF06199.11 EGO61561.1 - 0.066 13.3 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 1 0 Phage tail tube protein TsaE PF02367.17 EGO61561.1 - 0.089 12.8 0.5 22 5.1 0.0 3.0 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EGO61561.1 - 0.11 12.2 2.3 5.3 6.7 0.1 3.2 3 1 0 3 3 3 0 AAA domain DAP3 PF10236.9 EGO61561.1 - 0.12 11.5 1.0 5.8 6.0 0.1 2.7 2 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF87 PF01935.17 EGO61561.1 - 0.28 11.2 3.4 12 5.9 0.0 3.2 4 0 0 4 4 3 0 Helicase HerA, central domain Promethin PF16015.5 EGO61563.1 - 1.9e-22 79.2 8.0 2.9e-22 78.6 8.0 1.3 1 0 0 1 1 1 1 Promethin IncD PF17628.2 EGO61563.1 - 0.42 10.4 3.5 0.67 9.7 3.5 1.3 1 0 0 1 1 1 0 Inclusion membrane protein D S1FA PF04689.13 EGO61565.1 - 0.12 12.5 0.7 0.65 10.2 0.0 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA LIDHydrolase PF10230.9 EGO61566.1 - 1.6e-56 191.8 0.1 1e-42 146.6 0.0 2.1 2 0 0 2 2 2 2 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 EGO61566.1 - 0.0021 18.7 0.0 0.003 18.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGO61566.1 - 0.033 13.4 0.0 0.71 9.1 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Connexin PF00029.19 EGO61567.1 - 0.0031 17.3 0.6 0.0041 16.9 0.6 1.2 1 0 0 1 1 1 1 Connexin Mito_carr PF00153.27 EGO61567.1 - 0.0063 16.4 0.0 0.03 14.3 0.0 2.2 2 1 0 2 2 2 1 Mitochondrial carrier protein Zip PF02535.22 EGO61567.1 - 0.037 13.3 9.4 0.06 12.5 9.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3292 PF11696.8 EGO61567.1 - 0.98 7.7 6.2 1.4 7.2 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) SelP_N PF04592.14 EGO61567.1 - 1.8 7.9 29.3 2.8 7.3 29.3 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3984 PF13136.6 EGO61567.1 - 5.6 6.3 27.9 5.7 6.2 23.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) Shisa PF13908.6 EGO61571.1 - 0.0072 16.6 0.3 0.011 15.9 0.3 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator SdpI PF13630.6 EGO61571.1 - 0.028 14.5 5.3 0.055 13.6 5.3 1.5 1 0 0 1 1 1 0 SdpI/YhfL protein family EphA2_TM PF14575.6 EGO61571.1 - 0.034 15.0 0.3 0.11 13.4 0.3 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Wzy_C PF04932.15 EGO61571.1 - 0.052 13.2 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 O-Antigen ligase Prominin PF05478.11 EGO61571.1 - 0.74 7.7 3.5 1.1 7.2 3.5 1.1 1 0 0 1 1 1 0 Prominin Ly49 PF08391.10 EGO61571.1 - 3.7 7.9 4.7 7.2 7.0 4.7 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region Glyco_transf_25 PF01755.17 EGO61573.1 - 1.9e-11 44.2 0.0 4e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) MFS_1 PF07690.16 EGO61574.1 - 6.7e-14 51.6 22.5 7.4e-14 51.4 21.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 EGO61574.1 - 0.027 12.4 0.1 0.049 11.6 0.0 1.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TMEM132D_C PF15706.5 EGO61574.1 - 0.057 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term ABC2_membrane PF01061.24 EGO61575.1 - 1.4e-82 276.2 42.2 1.3e-46 158.7 15.6 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGO61575.1 - 6.5e-43 146.5 0.0 4.4e-19 69.4 0.0 3.4 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 EGO61575.1 - 6.6e-29 99.7 6.3 3.9e-25 87.6 0.0 3.7 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 EGO61575.1 - 7.2e-08 31.9 34.2 3.2e-06 26.5 16.4 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 EGO61575.1 - 3.9e-07 30.6 0.1 1e-06 29.3 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EGO61575.1 - 6e-06 26.7 0.2 0.029 14.8 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EGO61575.1 - 0.0001 22.0 0.2 0.0041 16.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGO61575.1 - 0.00015 22.0 0.1 0.53 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGO61575.1 - 0.0002 21.3 0.2 0.013 15.4 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EGO61575.1 - 0.00039 20.7 0.0 1.4 9.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EGO61575.1 - 0.00048 19.8 0.3 0.084 12.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EGO61575.1 - 0.0014 19.2 0.0 3.4 8.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EGO61575.1 - 0.0044 17.3 1.2 1.3 9.3 0.6 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EGO61575.1 - 0.0077 15.8 2.2 1.9 8.1 0.5 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EGO61575.1 - 0.013 14.8 0.6 4.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 EGO61575.1 - 0.025 15.0 0.1 3.8 7.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EGO61575.1 - 0.046 13.6 0.3 3 7.7 0.1 2.3 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 EGO61575.1 - 0.095 12.8 0.5 17 5.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 EGO61575.1 - 0.12 12.8 0.2 5.9 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EGO61575.1 - 0.15 11.8 0.0 3.8 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EGO61575.1 - 0.18 11.5 2.3 6.7 6.4 0.3 2.6 3 0 0 3 3 3 0 AAA domain DnaB_C PF03796.15 EGO61575.1 - 0.22 10.8 0.0 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Fungal_trans PF04082.18 EGO61576.1 - 4e-11 42.5 0.0 4e-11 42.5 0.0 2.6 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO61576.1 - 1.2e-06 28.5 9.0 2.2e-06 27.7 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Jiraiya PF15038.6 EGO61576.1 - 0.1 12.0 2.4 0.19 11.2 2.4 1.4 1 0 0 1 1 1 0 Jiraiya Zip PF02535.22 EGO61576.1 - 0.93 8.7 5.1 1.5 8.0 5.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF853 PF05872.12 EGO61578.1 - 0.098 11.2 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) zf-ribbon_3 PF13248.6 EGO61578.1 - 1.8 8.1 11.6 0.54 9.7 0.3 3.7 4 0 0 4 4 4 0 zinc-ribbon domain SET PF00856.28 EGO61580.1 - 6.2e-18 65.7 0.1 1.8e-17 64.2 0.0 1.8 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EGO61580.1 - 7.7e-06 26.6 0.0 1.6e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Spt5_N PF11942.8 EGO61580.1 - 1.6 9.8 16.5 3.7 8.6 2.9 3.8 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Ribonucleas_3_3 PF14622.6 EGO61581.1 - 4.5e-34 117.4 0.0 7.1e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like HAT_KAT11 PF08214.11 EGO61582.1 - 1e-100 337.5 0.0 1.6e-100 336.9 0.0 1.3 1 0 0 1 1 1 1 Histone acetylation protein DUF4757 PF15949.5 EGO61582.1 - 2.1 8.8 6.4 0.6 10.6 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4757) FA_desaturase PF00487.24 EGO61585.1 - 1.2 8.9 6.1 2.1 8.1 6.1 1.4 1 0 0 1 1 1 0 Fatty acid desaturase TRI12 PF06609.13 EGO61586.1 - 4.3e-23 81.6 15.0 6.7e-23 81.0 15.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EGO61586.1 - 6.9e-21 74.5 47.6 6.4e-20 71.4 47.6 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.11 EGO61586.1 - 0.08 13.3 0.1 0.08 13.3 0.1 5.0 4 3 2 6 6 6 0 Domain of unknown function (DUF1772) DUF2922 PF11148.8 EGO61586.1 - 0.16 11.7 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) Saf_2TM PF18303.1 EGO61586.1 - 0.87 9.2 3.7 0.62 9.6 0.1 2.6 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain NDUF_B12 PF08122.12 EGO61586.1 - 5.1 7.2 6.6 5.5 7.1 0.2 3.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family FAD_binding_3 PF01494.19 EGO61587.1 - 2.3e-19 69.9 0.1 4.2e-12 46.0 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 EGO61587.1 - 1.6e-06 27.5 1.0 2.5e-06 26.8 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGO61587.1 - 3.9e-06 26.3 0.7 5e-05 22.7 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGO61587.1 - 5.2e-06 26.6 0.4 1.3e-05 25.3 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGO61587.1 - 5.3e-05 23.0 1.2 0.0013 18.3 0.9 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGO61587.1 - 0.00045 19.7 0.8 0.00068 19.1 0.4 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGO61587.1 - 0.00075 18.9 0.7 0.0015 17.9 0.7 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGO61587.1 - 0.0013 17.9 0.2 0.0018 17.4 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EGO61587.1 - 0.0013 17.5 0.5 0.0022 16.8 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EGO61587.1 - 0.0031 16.8 0.0 0.0048 16.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 EGO61587.1 - 0.0032 16.8 0.1 0.46 9.7 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EGO61587.1 - 0.011 15.0 0.5 0.035 13.4 0.3 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EGO61587.1 - 0.015 15.9 1.3 0.053 14.1 0.5 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 EGO61587.1 - 0.04 13.8 1.1 0.1 12.5 0.1 2.1 2 0 0 2 2 2 0 Rossmann-like domain ApbA PF02558.16 EGO61587.1 - 0.058 13.0 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 EGO61587.1 - 0.11 11.4 0.0 0.37 9.6 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase SE PF08491.10 EGO61587.1 - 0.15 11.0 0.0 0.33 10.0 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase NMT1 PF09084.11 EGO61588.1 - 0.00042 20.3 0.0 0.41 10.5 0.0 3.1 1 1 1 2 2 2 2 NMT1/THI5 like SBP_bac_3 PF00497.20 EGO61588.1 - 0.00065 19.2 0.0 0.2 11.0 0.0 2.6 2 1 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 EGO61588.1 - 0.0018 17.9 0.0 0.0037 16.9 0.0 1.5 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NAPRTase_N PF17767.1 EGO61588.1 - 0.043 14.2 0.1 0.066 13.6 0.1 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NMT1_2 PF13379.6 EGO61588.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 NMT1-like family Ytp1 PF10355.9 EGO61589.1 - 6.2e-69 232.3 26.5 5.3e-68 229.2 20.7 2.7 2 1 0 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EGO61589.1 - 5.6e-34 116.1 3.0 5.6e-34 116.1 3.0 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) MFS_1 PF07690.16 EGO61590.1 - 1.7e-38 132.5 61.2 3.5e-36 124.9 40.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGO61590.1 - 1e-10 41.1 40.8 1.3e-09 37.5 40.8 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4813 PF16072.5 EGO61590.1 - 0.16 11.6 2.1 0.36 10.5 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Spt5_N PF11942.8 EGO61590.1 - 0.16 12.9 3.9 0.27 12.2 3.9 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Acyltransferase PF01553.21 EGO61591.1 - 1.2e-24 86.4 0.0 1.8e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EGO61591.1 - 2e-14 53.4 0.1 3.6e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus NAD_kinase PF01513.21 EGO61592.1 - 2.6e-51 174.6 0.0 1e-50 172.6 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EGO61592.1 - 0.025 14.2 0.0 0.098 12.3 0.0 1.9 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain TauD PF02668.16 EGO61594.1 - 7.1e-34 117.8 0.0 9.5e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EGO61594.1 - 0.23 10.5 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 CsiD Zn_clus PF00172.18 EGO61595.1 - 0.085 13.0 5.4 0.22 11.7 5.4 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.17 EGO61596.1 - 1.5e-11 43.4 3.4 9.1e-06 25.4 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGO61596.1 - 5.3e-11 41.9 0.4 0.00011 21.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGO61596.1 - 2.8e-05 24.0 0.7 0.0019 18.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGO61596.1 - 0.00014 22.1 1.5 0.0052 17.1 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGO61596.1 - 0.00037 21.1 2.2 0.0073 16.9 0.8 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGO61596.1 - 0.0011 18.8 1.4 2.2 8.3 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat SPO22 PF08631.10 EGO61596.1 - 0.0011 18.5 0.2 0.53 9.7 0.0 3.0 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_11 PF13414.6 EGO61596.1 - 0.0041 16.8 0.6 2.9 7.7 0.4 2.7 2 0 0 2 2 2 2 TPR repeat Fis1_TPR_C PF14853.6 EGO61596.1 - 0.015 15.3 1.7 0.25 11.4 0.1 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 EGO61596.1 - 0.019 15.5 0.2 0.095 13.2 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGO61596.1 - 0.063 13.7 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGO61596.1 - 0.064 14.1 2.6 0.1 13.4 0.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGO61596.1 - 0.5 11.1 2.3 2 9.2 0.0 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat AA_permease_2 PF13520.6 EGO61602.1 - 8e-81 272.0 25.8 9.6e-81 271.8 25.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGO61602.1 - 5.7e-23 81.3 21.9 7.4e-23 80.9 21.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2619 PF10942.8 EGO61602.1 - 0.0083 16.2 0.4 0.045 13.8 0.4 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2619) Aa_trans PF01490.18 EGO61602.1 - 0.046 12.4 15.7 0.017 13.9 11.2 2.5 2 1 0 2 2 2 0 Transmembrane amino acid transporter protein tRNA-synt_1b PF00579.25 EGO61603.1 - 5.8e-55 186.7 0.0 8.3e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Sdh_cyt PF01127.22 EGO61604.1 - 1.2e-17 64.1 3.6 1.6e-17 63.7 3.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TAF6_C PF07571.13 EGO61605.1 - 1.6e-28 98.9 0.1 2.9e-28 98.0 0.1 1.5 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EGO61605.1 - 2e-21 75.9 0.0 5.6e-21 74.5 0.0 1.8 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EGO61605.1 - 0.03 14.7 0.2 0.072 13.5 0.1 1.6 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Mucin PF01456.17 EGO61606.1 - 0.1 12.6 9.8 0.14 12.2 9.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein MelC1 PF06236.11 EGO61606.1 - 0.46 10.6 6.2 0.74 9.9 6.2 1.3 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 Glyco_hydro_61 PF03443.14 EGO61608.1 - 1.8e-71 240.3 0.1 1.8e-71 240.3 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EGO61608.1 - 5.7e-13 48.6 14.9 1.5e-12 47.3 14.9 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain CSD PF00313.22 EGO61608.1 - 0.045 13.6 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain FSA_C PF10479.9 EGO61608.1 - 8.7 4.3 6.3 11 4.1 6.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Gly_transf_sug PF04488.15 EGO61609.1 - 3.7e-18 66.0 0.0 5.7e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EGO61609.1 - 0.039 13.3 0.1 0.067 12.5 0.0 1.4 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Fringe PF02434.16 EGO61610.1 - 4.6e-07 29.5 0.3 7.1e-06 25.6 0.3 2.2 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.26 EGO61610.1 - 9.2e-05 22.3 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 PAN domain Galactosyl_T PF01762.21 EGO61610.1 - 0.006 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase PAN_4 PF14295.6 EGO61610.1 - 0.037 13.9 0.6 0.071 13.0 0.6 1.4 1 0 0 1 1 1 0 PAN domain Oest_recep PF02159.15 EGO61610.1 - 0.19 12.2 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 Oestrogen receptor DUF1996 PF09362.10 EGO61611.1 - 5.4e-78 262.2 2.1 7.2e-78 261.8 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Beta-lactamase PF00144.24 EGO61615.1 - 1.8e-72 244.4 0.0 2.5e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EGO61615.1 - 0.0083 16.6 0.1 0.034 14.6 0.1 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3471) TPR_12 PF13424.6 EGO61616.1 - 3.4e-09 36.9 0.8 0.00034 20.9 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 EGO61616.1 - 7.3e-06 26.5 0.0 1.9e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EGO61616.1 - 2.1e-05 23.8 0.0 3.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.17 EGO61616.1 - 0.00014 21.7 1.9 13 6.2 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGO61616.1 - 0.00054 19.7 0.4 1.9 8.4 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGO61616.1 - 0.0041 17.3 0.2 0.28 11.4 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGO61616.1 - 0.0048 16.7 0.6 3.4 7.6 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGO61616.1 - 0.012 15.1 0.1 0.094 12.1 0.0 2.0 2 1 0 2 2 2 0 MalT-like TPR region AAA_22 PF13401.6 EGO61616.1 - 0.026 14.8 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_19 PF14559.6 EGO61616.1 - 0.055 14.0 0.1 0.92 10.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TniB PF05621.11 EGO61616.1 - 0.09 12.2 0.0 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 Bacterial TniB protein AAA_25 PF13481.6 EGO61616.1 - 0.094 12.3 0.0 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EGO61616.1 - 0.12 11.7 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 EGO61616.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 EGO61616.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) HeH PF12949.7 EGO61616.1 - 0.18 11.5 0.0 0.61 9.8 0.0 1.9 2 0 0 2 2 2 0 HeH/LEM domain adh_short PF00106.25 EGO61617.1 - 9.8e-30 103.5 0.0 5.9e-22 78.1 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGO61617.1 - 1.2e-16 61.1 0.0 2.9e-13 49.9 0.0 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.19 EGO61617.1 - 0.06 12.7 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Thymidylate_kin PF02223.17 EGO61622.1 - 4.7e-41 140.5 0.1 2.5e-39 134.9 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 EGO61622.1 - 0.0013 19.0 0.1 0.0027 18.0 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGO61622.1 - 0.0066 17.0 0.0 0.01 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EGO61622.1 - 0.037 13.5 0.0 0.073 12.5 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 PRK PF00485.18 EGO61622.1 - 0.044 13.5 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CPT PF07931.12 EGO61622.1 - 0.11 12.4 0.6 0.31 10.9 0.0 1.9 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein GTP_cyclohydroI PF01227.22 EGO61623.1 - 9.2e-75 250.0 0.3 1e-74 249.8 0.3 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EGO61623.1 - 0.0039 17.3 0.0 0.0068 16.5 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein TAFII28 PF04719.14 EGO61624.1 - 4.8e-30 103.5 0.6 4e-26 90.9 0.0 2.3 2 0 0 2 2 2 2 hTAFII28-like protein conserved region CFEM PF05730.11 EGO61626.1 - 8.3e-12 45.0 12.4 1e-11 44.7 12.4 1.1 1 0 0 1 1 1 1 CFEM domain DUF1664 PF07889.12 EGO61627.1 - 0.067 13.2 19.4 1.8 8.6 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) CALCOCO1 PF07888.11 EGO61627.1 - 0.26 10.1 32.6 0.12 11.2 17.1 2.4 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Leu_zip PF15294.6 EGO61627.1 - 0.7 9.3 29.1 0.22 11.0 12.0 2.2 1 1 1 2 2 2 0 Leucine zipper UCH_C PF18031.1 EGO61627.1 - 1.1 9.2 8.4 0.073 13.0 2.0 2.5 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases Fez1 PF06818.15 EGO61627.1 - 5.4 7.4 30.7 2.8 8.4 13.8 2.8 1 1 1 2 2 2 0 Fez1 Cep57_MT_bd PF06657.13 EGO61627.1 - 6.4 7.3 10.2 6.4 7.3 1.4 3.4 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 IFT57 PF10498.9 EGO61627.1 - 7.6 5.4 23.7 13 4.7 23.7 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Macoilin PF09726.9 EGO61627.1 - 8.9 4.7 30.6 2.4 6.6 21.4 2.4 2 0 0 2 2 2 0 Macoilin family Exo_endo_phos PF03372.23 EGO61628.1 - 1.4e-15 57.5 0.1 8e-15 55.0 0.1 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 EGO61628.1 - 6e-09 36.0 3.2 0.0013 19.1 0.3 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGO61628.1 - 1e-06 28.4 2.0 5.9e-06 26.0 1.2 2.3 1 1 1 2 2 2 2 Leucine rich repeat HDV_ag PF01517.18 EGO61628.1 - 0.0094 15.8 0.8 0.016 15.0 0.8 1.3 1 0 0 1 1 1 1 Hepatitis delta virus delta antigen ssDBP PF17878.1 EGO61628.1 - 0.052 13.8 0.1 0.87 9.9 0.0 2.6 2 0 0 2 2 2 0 Single-stranded DNA-binding protein 4HBT_2 PF13279.6 EGO61631.1 - 1.7e-25 89.9 0.2 2.7e-25 89.2 0.2 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EGO61631.1 - 0.0046 17.3 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 Thioesterase superfamily Complex1_LYR PF05347.15 EGO61632.1 - 5.1e-08 32.8 0.1 5.9e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGO61632.1 - 3.3e-05 24.5 0.3 3.7e-05 24.4 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Methyltransf_25 PF13649.6 EGO61633.1 - 2.5e-11 44.1 0.0 1.6e-06 28.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EGO61633.1 - 2.4e-07 30.7 0.0 0.0021 17.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGO61633.1 - 4.6e-07 30.4 0.0 1.3e-05 25.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGO61633.1 - 5.1e-07 29.7 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGO61633.1 - 0.0002 22.1 0.0 0.0014 19.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain CheR PF01739.18 EGO61633.1 - 0.0067 15.9 0.0 0.03 13.8 0.0 1.9 1 1 0 1 1 1 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 EGO61633.1 - 0.0078 15.6 0.0 2.2 7.5 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Cerato-platanin PF07249.12 EGO61635.1 - 1.2e-64 215.7 3.1 1.4e-64 215.5 3.1 1.0 1 0 0 1 1 1 1 Cerato-platanin Zn_clus PF00172.18 EGO61637.1 - 2.1e-10 40.6 10.4 3.7e-10 39.8 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGO61637.1 - 2.3e-08 33.4 3.4 2.3e-08 33.4 3.4 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Thioesterase PF00975.20 EGO61640.1 - 1.7e-08 34.9 0.1 0.007 16.5 0.0 3.4 2 1 1 3 3 3 2 Thioesterase domain Abhydrolase_6 PF12697.7 EGO61640.1 - 0.0018 18.9 0.0 0.0027 18.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Mito_carr PF00153.27 EGO61641.1 - 9.3e-16 57.5 4.5 9.3e-06 25.5 0.1 4.9 3 2 0 3 3 3 3 Mitochondrial carrier protein Fer2 PF00111.27 EGO61642.1 - 5.8e-12 45.4 0.8 8.5e-12 44.9 0.8 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ECSIT PF06239.11 EGO61644.1 - 0.68 9.0 2.0 12 4.9 0.0 2.5 2 1 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway Ribosomal_S9 PF00380.19 EGO61647.1 - 0.14 12.7 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S9/S16 YbgT_YccB PF08173.11 EGO61650.1 - 0.24 11.6 3.3 0.71 10.1 3.3 1.8 1 0 0 1 1 1 0 Membrane bound YbgT-like protein Aminotran_5 PF00266.19 EGO61651.1 - 1.3e-25 90.1 0.0 2.6e-11 43.1 0.0 3.8 3 1 0 3 3 3 3 Aminotransferase class-V DUF3246 PF11596.8 EGO61652.1 - 0.15 11.5 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF1689 PF07954.11 EGO61653.1 - 0.043 14.2 0.0 0.049 14.1 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1689) F_bP_aldolase PF01116.20 EGO61654.1 - 1.9e-92 309.7 0.0 2.2e-92 309.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II ABM PF03992.16 EGO61655.1 - 6.7e-08 32.5 0.1 1.3e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Fimbrillin_C PF15495.6 EGO61657.1 - 0.0073 16.7 0.0 0.0084 16.5 0.0 1.1 1 0 0 1 1 1 1 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal PGBA_C PF15437.6 EGO61660.1 - 0.074 13.4 0.9 0.16 12.3 0.9 1.5 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal PTP_tm PF18861.1 EGO61660.1 - 0.091 12.8 0.2 0.091 12.8 0.2 1.6 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Amnionless PF14828.6 EGO61660.1 - 0.23 10.3 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Amnionless VPDSG-CTERM PF18205.1 EGO61660.1 - 0.63 9.9 5.3 1.2 9.0 5.3 1.5 1 0 0 1 1 1 0 VPDSG-CTERM motif DUF89 PF01937.19 EGO61662.1 - 7.9e-132 439.5 0.0 9.1e-132 439.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Fungal_trans PF04082.18 EGO61665.1 - 2.4e-13 49.7 0.1 3.6e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGO61665.1 - 2.6e-12 46.7 22.3 1.2e-07 31.7 9.4 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain UvdE PF03851.14 EGO61667.1 - 8.5e-129 428.7 0.0 1.2e-128 428.2 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE MliC PF09864.9 EGO61670.1 - 0.025 14.5 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme CENP-C_C PF11699.8 EGO61671.1 - 0.055 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Mif2/CENP-C like DUF5401 PF17380.2 EGO61672.1 - 8.9 4.2 6.6 14 3.6 6.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Ribosomal_L27 PF01016.19 EGO61673.1 - 6.6e-27 93.4 1.8 3.2e-26 91.2 0.0 2.4 2 0 0 2 2 2 1 Ribosomal L27 protein ECR1_N PF14382.6 EGO61673.1 - 0.003 17.3 0.1 0.006 16.4 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Pox_F17 PF04767.12 EGO61673.1 - 0.89 10.1 4.1 2.6 8.6 4.1 1.8 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein DUF2076 PF09849.9 EGO61674.1 - 0.021 14.8 1.9 0.026 14.6 1.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) IPP-2 PF04979.14 EGO61675.1 - 2.7e-23 83.2 7.3 2.7e-23 83.2 7.3 1.7 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Sugar_tr PF00083.24 EGO61676.1 - 1.3e-85 288.0 18.7 1.6e-85 287.7 18.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGO61676.1 - 1.1e-13 50.9 28.5 6.5e-09 35.2 18.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S12 PF17487.2 EGO61676.1 - 0.08 13.7 5.7 0.074 13.8 1.2 2.8 2 0 0 2 2 2 0 Ribosomal protein S12 MFS_1_like PF12832.7 EGO61676.1 - 0.24 10.2 11.5 0.012 14.6 2.7 2.3 2 1 0 2 2 2 0 MFS_1 like family Fungal_trans_2 PF11951.8 EGO61677.1 - 8.9e-07 28.0 0.3 0.0002 20.3 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain MIOX PF05153.15 EGO61678.1 - 3.1e-120 400.4 0.0 3.8e-120 400.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD_6 PF18019.1 EGO61678.1 - 0.034 14.3 0.2 0.081 13.0 0.0 1.7 1 1 0 2 2 2 0 HD domain NOA36 PF06524.12 EGO61680.1 - 5.8 6.1 10.2 9.2 5.5 10.2 1.3 1 0 0 1 1 1 0 NOA36 protein DUF1003 PF06210.11 EGO61681.1 - 0.085 13.0 0.8 0.19 11.9 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Lipase_3 PF01764.25 EGO61685.1 - 5.9e-20 71.6 0.0 9.8e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) MAP70 PF07058.11 EGO61685.1 - 4.4 5.9 10.0 6.6 5.4 10.0 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 RAI16-like PF10257.9 EGO61686.1 - 6.5e-73 245.7 2.1 1e-72 245.0 2.1 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein CDC27 PF09507.10 EGO61686.1 - 0.21 10.9 9.6 0.38 10.1 9.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.12 EGO61686.1 - 1 9.1 4.3 1.8 8.3 4.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 EGO61686.1 - 2.6 6.7 4.9 9.9 4.8 4.3 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein PARM PF17061.5 EGO61687.1 - 0.015 15.5 0.7 0.017 15.3 0.7 1.1 1 0 0 1 1 1 0 PARM CrgA PF06781.12 EGO61687.1 - 0.092 12.8 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Cell division protein CrgA DUF4679 PF15728.5 EGO61687.1 - 0.33 10.0 4.4 0.045 12.8 0.8 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4679) Apc13p PF05839.11 EGO61689.1 - 1.6e-37 127.5 0.2 2.4e-37 127.0 0.2 1.3 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.16 EGO61690.1 - 1.2e-41 141.8 0.0 1.4e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component TIP120 PF08623.10 EGO61691.1 - 1.9e-72 242.5 0.8 1e-69 233.6 0.0 3.8 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 EGO61691.1 - 1.6e-15 57.2 23.9 0.0013 19.1 0.1 9.3 7 3 4 11 11 11 5 HEAT repeats HEAT_EZ PF13513.6 EGO61691.1 - 1.9e-10 41.0 15.3 0.27 11.8 0.0 10.8 11 0 0 11 11 10 3 HEAT-like repeat HEAT PF02985.22 EGO61691.1 - 2.5e-09 36.6 31.2 0.19 12.1 0.1 11.4 13 0 0 13 13 13 4 HEAT repeat UME PF08064.13 EGO61691.1 - 1.2e-06 28.3 0.7 0.09 12.7 0.0 6.0 5 1 1 6 6 6 2 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 EGO61691.1 - 2.1e-06 28.3 1.6 0.013 16.1 0.0 6.1 6 2 1 7 7 7 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGO61691.1 - 2.4e-05 24.4 14.2 0.042 13.9 0.0 5.9 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EGO61691.1 - 0.00013 22.2 17.1 0.49 10.6 0.3 7.6 7 2 1 8 8 8 2 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 EGO61691.1 - 0.007 16.1 3.7 5 6.8 0.0 4.4 4 2 1 5 5 5 2 rRNA processing/ribosome biogenesis Ecm29 PF13001.7 EGO61691.1 - 0.027 13.1 7.7 2.3 6.8 0.0 5.9 7 1 0 7 7 7 0 Proteasome stabiliser RICTOR_N PF14664.6 EGO61691.1 - 0.027 13.5 7.6 2.2 7.2 1.2 3.9 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term PUL PF08324.11 EGO61691.1 - 0.15 11.3 6.5 0.097 11.9 1.0 3.2 3 1 0 3 3 3 0 PUL domain Nipped-B_C PF12830.7 EGO61691.1 - 0.16 11.9 0.8 14 5.6 0.0 4.0 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus U3snoRNP10 PF12397.8 EGO61691.1 - 0.22 11.9 10.1 0.57 10.5 1.7 4.2 4 0 0 4 4 4 0 U3 small nucleolar RNA-associated protein 10 IFRD PF05004.13 EGO61691.1 - 0.66 9.0 6.8 3.8 6.5 0.0 4.3 5 1 0 5 5 5 0 Interferon-related developmental regulator (IFRD) RNA_pol_3_Rpc31 PF11705.8 EGO61691.1 - 1.3 9.3 9.7 2.3 8.4 9.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Porphobil_deam PF01379.20 EGO61694.1 - 3.8e-72 242.1 0.0 5.5e-72 241.6 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EGO61694.1 - 5.1e-19 68.4 0.3 5.1e-19 68.4 0.3 1.8 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain PLAC8 PF04749.17 EGO61694.1 - 6.6e-09 36.7 0.1 1.2e-08 35.8 0.1 1.5 1 0 0 1 1 1 1 PLAC8 family Ras PF00071.22 EGO61695.1 - 1.2e-31 109.5 0.3 1.6e-31 109.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGO61695.1 - 6.3e-24 84.5 0.1 1.2e-23 83.6 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGO61695.1 - 3.8e-07 29.7 0.1 5.2e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGO61695.1 - 8.4e-05 22.0 0.2 0.00012 21.6 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EGO61695.1 - 0.00064 18.7 0.4 0.059 12.2 0.0 2.2 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) BRCT PF00533.26 EGO61697.1 - 0.00011 22.5 0.0 0.00026 21.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EGO61697.1 - 0.00032 20.5 0.0 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 EGO61697.1 - 0.0036 17.7 0.0 0.011 16.2 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 EGO61697.1 - 0.005 16.9 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Aa_trans PF01490.18 EGO61698.1 - 1.8e-19 69.7 29.3 9e-18 64.2 24.0 2.5 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein Med12-LCEWAV PF12145.8 EGO61699.1 - 0.041 12.7 0.0 0.053 12.4 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain vWF_A PF12450.8 EGO61701.1 - 0.11 12.4 0.2 0.14 12.1 0.2 1.1 1 0 0 1 1 1 0 von Willebrand factor GFO_IDH_MocA PF01408.22 EGO61704.1 - 4.1e-23 82.5 0.0 6.7e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGO61704.1 - 6.5e-15 55.1 0.0 1.2e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EGO61704.1 - 0.005 17.5 0.0 0.0099 16.5 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Neurospora_tetrasperma_FGSC_2508-v2.0/GCA_000213175.1_v2.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Neurospora_tetrasperma_FGSC_2508-v2.0/GCA_000213175.1_v2.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Neurospora_tetrasperma_FGSC_2508-v2.0/GCA_000213175.1_v2.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Neurospora_tetrasperma_FGSC_2508-v2.0/GCA_000213175.1_v2.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 01:40:58 2019 # [ok]