# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- CAF-1_p150 PF11600.3 EGO51325.1 - 0.0074 15.6 3.5 0.009 15.4 2.4 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal PRKCSH PF07915.8 EGO51325.1 - 0.23 12.3 1.3 19 6.1 0.2 2.3 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Dsh_C PF12316.3 EGO51325.1 - 3.3 7.7 14.6 6.3 6.8 10.1 1.5 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal RRM_1 PF00076.17 EGO51326.1 - 1.6e-14 53.2 0.0 2.2e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO51326.1 - 7.8e-12 45.0 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO51326.1 - 8.3e-07 28.7 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.22 EGO51327.1 - 4.6e-50 169.4 0.1 1.4e-26 93.4 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGO51327.1 - 1.3e-15 58.1 7.2 0.00015 21.8 0.6 4.1 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EGO51327.1 - 4.7e-13 48.8 0.7 0.0016 17.7 0.0 4.3 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGO51327.1 - 7.7e-10 39.4 0.0 0.00015 22.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Chromo PF00385.19 EGO51327.1 - 1.2e-09 37.6 0.0 2.4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.1 EGO51327.1 - 6e-09 35.3 0.4 0.0036 16.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EGO51327.1 - 4.1e-08 34.0 0.1 0.0061 17.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 EGO51327.1 - 4.1e-07 29.3 0.0 0.065 12.2 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 EGO51327.1 - 6.9e-07 29.2 0.0 0.0065 16.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EGO51327.1 - 2.3e-06 26.8 0.0 0.018 14.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EGO51327.1 - 2.9e-06 27.1 0.0 0.043 13.7 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EGO51327.1 - 5.5e-06 26.8 0.0 0.018 15.5 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 EGO51327.1 - 2.4e-05 23.9 1.0 0.31 10.4 0.1 3.4 3 0 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 EGO51327.1 - 2.9e-05 24.2 0.1 0.41 10.7 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EGO51327.1 - 0.00012 22.0 0.0 0.014 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGO51327.1 - 0.00026 21.2 0.1 0.096 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGO51327.1 - 0.00026 20.8 0.0 0.87 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGO51327.1 - 0.00045 19.6 0.0 0.96 8.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 EGO51327.1 - 0.00074 19.3 0.0 0.42 10.4 0.0 3.5 3 0 0 3 3 3 1 Dynamin family RNA_helicase PF00910.17 EGO51327.1 - 0.00079 19.5 0.1 2.2 8.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase ArgK PF03308.11 EGO51327.1 - 0.0011 17.7 0.8 0.57 8.9 0.1 2.5 2 0 0 2 2 2 2 ArgK protein MobB PF03205.9 EGO51327.1 - 0.002 17.8 0.1 0.35 10.5 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EGO51327.1 - 0.0023 17.6 0.3 1.3 8.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 EGO51327.1 - 0.0033 17.6 0.1 4.7 7.4 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HEAT_2 PF13646.1 EGO51327.1 - 0.0035 17.6 7.6 0.13 12.5 0.0 3.6 1 1 1 3 3 3 1 HEAT repeats DUF3584 PF12128.3 EGO51327.1 - 0.0045 14.4 0.6 0.14 9.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) HEAT PF02985.17 EGO51327.1 - 0.0048 16.8 0.5 35 4.8 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat DUF87 PF01935.12 EGO51327.1 - 0.005 16.6 2.6 0.39 10.5 0.1 3.3 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_30 PF13604.1 EGO51327.1 - 0.0053 16.3 0.5 5.3 6.5 0.0 3.3 4 0 0 4 4 2 0 AAA domain AAA_13 PF13166.1 EGO51327.1 - 0.0072 14.8 0.0 2.1 6.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EGO51327.1 - 0.01 15.3 0.1 1.3 8.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 EGO51327.1 - 0.014 14.3 0.1 2.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_10 PF05176.9 EGO51327.1 - 0.018 14.3 0.5 0.031 13.5 0.3 1.3 1 0 0 1 1 1 0 ATP10 protein AAA_14 PF13173.1 EGO51327.1 - 0.025 14.4 0.0 3.8 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EGO51327.1 - 0.047 13.1 0.8 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EGO51327.1 - 0.057 13.4 0.5 1.8 8.5 0.1 3.0 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 EGO51327.1 - 0.11 11.8 0.7 22 4.4 0.1 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 EGO51327.1 - 0.16 11.0 1.6 6.9 5.7 0.1 2.7 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 EGO51327.1 - 0.18 11.5 2.3 17 5.0 0.2 3.0 4 0 0 4 4 2 0 NTPase HEAT_EZ PF13513.1 EGO51327.1 - 0.24 11.9 2.3 54 4.4 0.0 4.0 3 1 1 4 4 4 0 HEAT-like repeat EBV-NA1 PF02905.9 EGO51328.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain Glyco_hydro_16 PF00722.16 EGO51329.1 - 1.6e-19 69.8 0.2 3.8e-19 68.7 0.1 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Arabinose_trans PF04602.7 EGO51329.1 - 0.031 12.4 0.1 0.058 11.5 0.1 1.3 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein Glyco_trans_2_3 PF13632.1 EGO51330.1 - 1.3e-46 158.7 3.7 4.3e-46 157.0 2.6 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EGO51330.1 - 6.8e-06 25.8 0.0 1.7e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGO51330.1 - 1.5e-05 24.9 0.0 3.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGO51330.1 - 0.0025 17.1 0.2 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 SSF PF00474.12 EGO51333.1 - 2.3e-21 75.9 29.4 2.8e-21 75.6 19.9 1.5 1 1 0 1 1 1 1 Sodium:solute symporter family HET PF06985.6 EGO51334.1 - 2.5e-22 79.5 0.0 5.6e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Formyl_trans_N PF00551.14 EGO51335.1 - 6.9e-37 126.7 0.1 8.7e-37 126.4 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 EGO51335.1 - 6.3e-09 35.1 0.0 1.6e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 EGO51335.1 - 0.00025 20.6 0.4 0.0014 18.3 0.0 2.2 2 1 0 2 2 2 1 ACT domain TroA PF01297.12 EGO51335.1 - 0.058 12.6 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Periplasmic solute binding protein family MFS_1 PF07690.11 EGO51336.1 - 2.1e-35 122.1 12.2 2.1e-35 122.1 8.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO51336.1 - 5.4e-16 58.2 5.5 2.1e-15 56.2 3.8 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EGO51336.1 - 2.9e-06 25.9 19.2 0.0003 19.3 2.6 3.8 2 2 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 EGO51336.1 - 7.1e-05 21.1 0.4 7.1e-05 21.1 0.3 2.1 3 0 0 3 3 3 1 Transmembrane secretion effector TRI12 PF06609.8 EGO51336.1 - 0.00027 19.3 1.8 0.00043 18.6 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 EGO51336.1 - 0.0011 17.7 0.1 2.2 6.8 0.0 3.0 1 1 0 3 3 3 2 BT1 family MFS_1_like PF12832.2 EGO51336.1 - 0.0013 18.5 0.3 0.15 11.8 0.0 3.4 3 0 0 3 3 3 1 MFS_1 like family Folate_carrier PF01770.13 EGO51336.1 - 0.022 13.3 0.0 0.032 12.7 0.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF3611 PF12263.3 EGO51336.1 - 0.026 13.9 0.1 0.23 10.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) ATG22 PF11700.3 EGO51336.1 - 0.36 9.2 16.6 0.033 12.6 4.7 2.8 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like MRJP PF03022.11 EGO51337.1 - 5.4e-29 101.3 0.0 3.2e-28 98.7 0.0 1.9 1 1 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 EGO51337.1 - 0.00019 20.8 0.0 0.0004 19.8 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Acetyltransf_1 PF00583.19 EGO51338.1 - 8.7e-09 35.3 0.0 1.4e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGO51338.1 - 2.2e-07 30.9 0.0 2.1e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGO51338.1 - 1.4e-06 28.1 0.0 0.0026 17.6 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO51338.1 - 0.0004 20.4 0.1 0.0014 18.7 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGO51338.1 - 0.053 13.4 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Fungal_trans PF04082.13 EGO51339.1 - 3.8e-06 25.9 0.0 5.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO51339.1 - 4.2 7.3 22.8 0.038 13.9 7.8 2.6 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EGO51341.1 - 5.6e-06 26.1 13.1 9e-06 25.5 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.19 EGO51342.1 - 2.9e-08 33.0 0.0 0.00061 18.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGO51342.1 - 8.9e-08 31.5 0.5 0.0025 16.9 0.1 2.6 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EGO51342.1 - 8.5e-05 22.5 0.9 0.00016 21.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO51342.1 - 0.0057 16.5 0.0 0.033 14.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CDI PF02234.14 EGO51342.1 - 0.5 10.2 0.1 0.5 10.2 0.0 3.1 3 0 0 3 3 3 0 Cyclin-dependent kinase inhibitor Chitin_bind_1 PF00187.14 EGO51343.1 - 2.8e-15 56.0 75.4 6.1e-07 29.3 12.0 4.5 3 3 0 3 3 3 3 Chitin recognition protein Mucin PF01456.12 EGO51343.1 - 0.092 12.5 29.4 0.092 12.5 5.5 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Transferase PF02458.10 EGO51344.1 - 1.3e-22 79.8 0.0 3e-12 45.7 0.0 3.3 2 1 0 2 2 2 2 Transferase family MIP PF00230.15 EGO51345.1 - 9.4e-47 159.3 19.9 1.3e-46 158.9 13.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF1201 PF06716.6 EGO51345.1 - 0.78 9.6 9.7 0.42 10.4 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1201) Cofilin_ADF PF00241.15 EGO51346.1 - 5.4e-14 52.1 0.0 6.1e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Glyco_hydro_3 PF00933.16 EGO51347.1 - 1.2e-93 313.4 0.0 2e-93 312.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO51347.1 - 1.6e-59 201.1 0.0 1.2e-58 198.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGO51347.1 - 8.4e-21 73.6 0.1 2.1e-20 72.3 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain bZIP_1 PF00170.16 EGO51347.1 - 1.5e-09 37.6 5.1 3.4e-09 36.5 3.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGO51347.1 - 1.7e-07 30.9 9.8 3.2e-07 30.0 6.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper CDC27 PF09507.5 EGO51347.1 - 0.0024 17.1 0.4 0.0059 15.8 0.3 1.6 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 bZIP_Maf PF03131.12 EGO51347.1 - 0.076 13.3 2.0 0.16 12.2 1.4 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Macoilin PF09726.4 EGO51347.1 - 0.54 8.4 3.1 0.74 8.0 2.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Takusan PF04822.8 EGO51347.1 - 0.63 9.8 3.1 1.2 8.8 2.1 1.4 1 0 0 1 1 1 0 Takusan Atg14 PF10186.4 EGO51347.1 - 5.4 5.8 5.4 8.3 5.2 3.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ABC2_membrane PF01061.19 EGO51348.1 - 6.1e-85 283.6 42.3 4.8e-46 156.5 7.1 2.8 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EGO51348.1 - 1.4e-32 111.4 1.3 8.5e-26 89.6 0.0 2.9 2 1 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EGO51348.1 - 2.4e-26 92.6 0.2 1.3e-16 61.1 0.1 2.5 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 EGO51348.1 - 0.00021 20.5 0.0 0.00039 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EGO51348.1 - 0.00038 20.5 0.3 0.15 12.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 EGO51348.1 - 0.0004 19.8 0.1 0.0007 19.0 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EGO51348.1 - 0.0011 18.9 0.2 0.0032 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGO51348.1 - 0.0025 18.1 0.1 0.013 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGO51348.1 - 0.0054 16.1 0.1 0.039 13.3 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 EGO51348.1 - 0.0074 16.4 0.0 0.13 12.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGO51348.1 - 0.009 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO51348.1 - 0.0098 15.8 0.1 0.025 14.5 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EGO51348.1 - 0.015 16.0 0.0 0.11 13.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EGO51348.1 - 0.035 13.7 0.3 0.087 12.4 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 EGO51348.1 - 0.035 14.0 0.0 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EGO51348.1 - 0.044 13.2 0.1 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EGO51348.1 - 0.045 13.2 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 EGO51348.1 - 0.1 12.0 0.2 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EGO51348.1 - 0.16 10.9 0.1 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Septin ABC2_membrane_3 PF12698.2 EGO51348.1 - 1 8.3 40.2 0.51 9.3 8.6 2.9 2 1 0 2 2 2 0 ABC-2 family transporter protein adh_short PF00106.20 EGO51349.1 - 3.5e-18 66.0 0.0 1.5e-17 64.0 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO51349.1 - 2.5e-16 60.1 0.0 1.8e-14 54.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO51349.1 - 5.2e-09 36.0 0.0 1.2e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 KR domain RDM PF11002.3 EGO51349.1 - 0.013 15.1 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 RFPL defining motif (RDM) DUF1776 PF08643.5 EGO51349.1 - 0.037 13.1 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.13 EGO51350.1 - 1.2e-27 96.7 0.0 1.8e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EGO51350.1 - 2e-10 40.9 0.0 3.8e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ldl_recept_b PF00058.12 EGO51350.1 - 7.7e-08 32.5 0.0 0.089 13.1 0.0 4.9 5 0 0 5 5 5 2 Low-density lipoprotein receptor repeat class B NAD_Gly3P_dh_N PF01210.18 EGO51350.1 - 0.00014 21.6 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Arylesterase PF01731.15 EGO51350.1 - 0.0029 17.5 0.0 0.3 11.1 0.0 3.2 3 0 0 3 3 3 1 Arylesterase PQQ PF01011.16 EGO51350.1 - 0.0033 16.8 0.0 0.0099 15.3 0.0 1.7 1 0 0 1 1 1 1 PQQ enzyme repeat SGL PF08450.7 EGO51350.1 - 0.014 14.7 0.0 2.9 7.2 0.0 3.0 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EGO51350.1 - 0.049 13.6 0.0 29 4.8 0.0 3.2 2 1 0 2 2 2 0 Strictosidine synthase Notch PF00066.12 EGO51350.1 - 3.7 7.8 5.9 5.8 7.2 1.1 2.4 2 0 0 2 2 2 0 LNR domain NAD_binding_1 PF00175.16 EGO51351.1 - 4.6e-30 104.3 0.0 1.6e-29 102.6 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGO51351.1 - 4.2e-29 100.5 0.0 8.2e-29 99.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EGO51351.1 - 5.9e-23 80.4 0.1 1e-22 79.6 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EGO51351.1 - 0.0011 18.8 0.0 0.0089 15.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EGO51351.1 - 0.003 17.4 0.1 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain p450 PF00067.17 EGO51353.1 - 2.9e-66 223.8 0.0 3.5e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 EGO51354.1 - 7.2e-07 29.0 9.5 1.6e-06 27.9 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain C2 PF00168.25 EGO51355.1 - 6.2e-24 83.6 0.0 3.6e-14 52.3 0.0 2.7 2 0 0 2 2 2 2 C2 domain SIMPL PF04402.9 EGO51356.1 - 0.042 13.7 0.2 0.082 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Aa_trans PF01490.13 EGO51357.1 - 6.7e-91 304.7 13.3 9.1e-91 304.3 9.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EGO51357.1 - 5.4e-05 22.1 17.6 0.00011 21.2 12.2 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Polysacc_syn_2C PF08485.5 EGO51358.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal SH3_1 PF00018.23 EGO51359.1 - 1.5e-08 33.9 0.1 2.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGO51359.1 - 8.1e-08 31.6 0.0 1.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EGO51359.1 - 4.2e-06 26.2 0.0 8.8e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4491 PF14898.1 EGO51359.1 - 0.12 12.4 1.6 0.3 11.2 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) DASH_Spc19 PF08287.6 EGO51360.1 - 2.8e-45 153.6 0.1 3.8e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Spc19 DUF1843 PF08898.5 EGO51360.1 - 0.18 11.8 2.3 6.2 6.9 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DZR PF12773.2 EGO51362.1 - 0.037 13.8 4.6 0.079 12.7 3.2 1.7 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EGO51362.1 - 0.047 13.2 3.4 0.047 13.2 2.4 2.6 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.7 EGO51362.1 - 0.47 10.2 4.1 0.22 11.3 0.9 1.7 1 1 1 2 2 2 0 zinc-ribbons DUF4215 PF13948.1 EGO51362.1 - 2.5 8.3 5.5 14 6.0 3.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4215) DNA_ligase_ZBD PF03119.11 EGO51362.1 - 7.6 6.3 10.9 7.9 6.2 0.1 3.4 3 1 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain zf-ribbon_3 PF13248.1 EGO51362.1 - 9.7 5.5 13.2 0.39 9.9 2.1 3.2 3 2 0 3 3 3 0 zinc-ribbon domain YjeF_N PF03853.10 EGO51363.1 - 1.3e-35 122.4 0.0 1.6e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.14 EGO51364.1 - 3.1e-25 87.6 0.4 8.5e-25 86.2 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S16 Glyco_hydro_16 PF00722.16 EGO51366.1 - 4.8e-43 146.5 2.6 1e-42 145.4 1.8 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TMEM51 PF15345.1 EGO51366.1 - 0.037 13.7 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Phage_DNA_bind PF02303.12 EGO51366.1 - 0.05 13.6 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Helix-destabilising protein Mid2 PF04478.7 EGO51366.1 - 0.16 11.3 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF717 PF05338.7 EGO51367.1 - 0.0019 18.0 4.5 0.28 11.1 0.1 3.7 3 1 1 4 4 4 2 Protein of unknown function (DUF717) Tropomyosin_1 PF12718.2 EGO51367.1 - 0.0022 17.8 1.1 0.0022 17.8 0.8 3.4 1 1 2 3 3 3 1 Tropomyosin like Laminin_II PF06009.7 EGO51367.1 - 0.07 12.8 32.7 0.12 12.1 2.0 3.7 1 1 2 4 4 4 0 Laminin Domain II NPV_P10 PF05531.7 EGO51367.1 - 0.091 13.0 0.6 0.091 13.0 0.4 6.0 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 EGO51367.1 - 0.45 8.3 27.2 0.72 7.6 18.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.6 EGO51367.1 - 0.57 10.1 14.4 1.7 8.5 0.3 5.5 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.4 EGO51367.1 - 1.7 8.8 33.9 1.1 9.4 0.2 6.0 1 1 6 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pilt PF15453.1 EGO51367.1 - 2.8 7.5 19.1 0.7 9.5 8.0 2.1 2 0 0 2 2 2 0 Protein incorporated later into Tight Junctions ADIP PF11559.3 EGO51368.1 - 0.0084 16.0 6.4 0.022 14.6 4.3 1.7 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding GrpE PF01025.14 EGO51368.1 - 0.02 14.4 7.5 0.084 12.4 0.5 2.1 1 1 1 2 2 2 0 GrpE BRE1 PF08647.6 EGO51368.1 - 0.029 14.3 4.0 0.034 14.1 0.4 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Prominin PF05478.6 EGO51368.1 - 0.032 11.7 0.1 0.051 11.1 0.1 1.3 1 1 0 1 1 1 0 Prominin Fib_alpha PF08702.5 EGO51368.1 - 0.047 13.8 2.8 0.068 13.2 2.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 EGO51368.1 - 0.12 12.2 0.9 0.5 10.1 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 EGO51368.1 - 0.15 11.6 8.0 0.4 10.2 1.2 2.0 1 1 0 2 2 2 0 IncA protein DivIC PF04977.10 EGO51368.1 - 0.16 11.4 4.1 4.9 6.7 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator H-kinase_dim PF02895.9 EGO51368.1 - 0.18 12.1 2.6 1.9 8.8 0.7 2.3 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain FlaC_arch PF05377.6 EGO51368.1 - 0.24 11.3 1.9 1.1 9.1 0.3 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.16 EGO51368.1 - 0.81 9.6 7.6 0.26 11.2 0.4 2.6 2 2 0 2 2 2 0 bZIP transcription factor DUF972 PF06156.8 EGO51368.1 - 1 9.7 4.5 1.1 9.6 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EGO51368.1 - 1.1 9.0 6.4 1.2 9.0 1.0 2.7 2 1 0 2 2 2 0 Basic region leucine zipper Sec2p PF06428.6 EGO51368.1 - 1.4 8.8 6.3 0.34 10.7 1.1 2.0 1 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Cep57_CLD_2 PF14197.1 EGO51368.1 - 1.8 8.5 9.3 0.37 10.7 2.2 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 TMF_DNA_bd PF12329.3 EGO51368.1 - 2 8.2 10.4 1.1 9.0 0.9 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Amidase PF01425.16 EGO51369.1 - 0.0052 15.7 0.7 0.029 13.2 0.0 2.1 2 0 0 2 2 2 1 Amidase TPR_11 PF13414.1 EGO51370.1 - 1.5e-08 34.1 6.5 0.00067 19.2 0.0 5.2 5 2 2 7 7 7 2 TPR repeat TPR_2 PF07719.12 EGO51370.1 - 2.3e-07 30.1 9.3 0.34 10.9 0.0 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGO51370.1 - 0.00039 19.9 1.5 1.6 8.7 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGO51370.1 - 0.00084 19.2 9.9 0.0027 17.5 0.3 5.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO51370.1 - 0.0024 18.4 18.6 0.16 12.6 0.9 6.7 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGO51370.1 - 0.0025 18.1 8.7 0.065 13.5 0.1 5.2 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO51370.1 - 0.012 15.7 0.1 21 5.6 0.0 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGO51370.1 - 0.013 15.2 0.0 3.7 7.5 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGO51370.1 - 0.013 15.0 3.8 3.2 7.4 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGO51370.1 - 0.041 14.5 16.6 10 7.0 0.1 7.4 8 0 0 8 8 7 0 Tetratricopeptide repeat Apc3 PF12895.2 EGO51370.1 - 0.046 13.8 4.2 0.42 10.7 0.0 3.9 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EGO51370.1 - 0.25 11.8 11.8 0.59 10.7 0.7 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4074 PF13293.1 EGO51371.1 - 0.56 10.4 5.9 0.31 11.2 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4074) Herpes_UL25 PF01499.11 EGO51372.1 - 0.16 10.2 6.4 0.91 7.7 4.0 1.8 1 1 1 2 2 2 0 Herpesvirus UL25 family TATR PF03430.8 EGO51372.1 - 0.87 8.1 9.7 1.1 7.8 6.7 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Hid1 PF12722.2 EGO51372.1 - 2.8 5.4 10.2 3.4 5.2 7.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1191 PF06697.7 EGO51375.1 - 0.033 13.0 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Glycophorin_A PF01102.13 EGO51375.1 - 0.05 13.3 0.1 0.05 13.3 0.1 2.1 2 1 0 2 2 2 0 Glycophorin A NicO PF03824.11 EGO51375.1 - 0.053 12.8 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein EphA2_TM PF14575.1 EGO51375.1 - 0.077 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4190 PF13828.1 EGO51376.1 - 0.016 14.7 1.4 0.016 14.7 0.9 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) DUF2613 PF11021.3 EGO51376.1 - 0.87 9.3 4.1 1 9.0 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF454 PF04304.8 EGO51376.1 - 2.1 8.4 7.0 0.53 10.3 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF454) DUF4448 PF14610.1 EGO51377.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1049 PF06305.6 EGO51377.1 - 0.22 11.0 1.8 1.3 8.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) SNN_transmemb PF09049.5 EGO51377.1 - 0.36 10.5 3.7 0.74 9.5 2.6 1.5 1 0 0 1 1 1 0 Stannin transmembrane RDD PF06271.7 EGO51378.1 - 0.062 13.2 0.0 0.076 12.9 0.0 1.1 1 0 0 1 1 1 0 RDD family m04gp34like PF12216.3 EGO51378.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Immune evasion protein DUF2142 PF09913.4 EGO51379.1 - 0.15 10.6 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) SKG6 PF08693.5 EGO51380.1 - 0.0041 16.3 1.4 0.01 15.0 1.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TOH_N PF12549.3 EGO51380.1 - 0.0082 15.6 0.1 0.0082 15.6 0.1 2.8 2 0 0 2 2 2 1 Tyrosine hydroxylase N terminal VPEP PF07589.6 EGO51380.1 - 0.44 10.5 3.8 1.1 9.1 2.6 1.7 1 0 0 1 1 1 0 PEP-CTERM motif Glyco_hydro_26 PF02156.10 EGO51382.1 - 1.6e-13 50.8 3.6 1.7e-13 50.7 1.6 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 26 Rpp20 PF12328.3 EGO51386.1 - 1.9e-27 95.7 0.0 2.4e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EGO51386.1 - 5.4e-20 70.7 0.0 7.8e-20 70.2 0.0 1.2 1 0 0 1 1 1 1 Alba Rogdi_lz PF10259.4 EGO51387.1 - 1e-75 254.3 0.0 5.6e-74 248.6 0.0 2.0 2 0 0 2 2 2 2 Rogdi leucine zipper containing protein NIPSNAP PF07978.8 EGO51388.1 - 7e-33 112.6 6.3 1.4e-29 102.0 0.1 2.7 3 0 0 3 3 3 2 NIPSNAP ATP-synt_J PF04911.7 EGO51389.1 - 2.7e-26 90.7 0.2 3e-26 90.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase j chain FSH1 PF03959.8 EGO51390.1 - 5.4e-57 192.6 0.0 8.5e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EGO51390.1 - 8.8e-08 32.3 0.0 5e-05 23.2 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO51390.1 - 1.3e-06 28.2 0.0 2.4e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGO51390.1 - 9.9e-05 21.8 0.1 0.096 12.1 0.3 3.1 3 1 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.13 EGO51390.1 - 0.094 11.9 0.0 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family FimP PF09766.4 EGO51393.1 - 0.0022 17.1 6.7 0.0035 16.4 4.6 1.2 1 0 0 1 1 1 1 Fms-interacting protein Spt20 PF12090.3 EGO51393.1 - 0.039 13.3 3.3 0.066 12.5 2.3 1.3 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 EGO51393.1 - 0.08 12.6 6.1 0.15 11.7 4.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 EGO51393.1 - 0.14 10.3 14.9 0.22 9.6 10.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GN3L_Grn1 PF08701.6 EGO51393.1 - 0.4 10.6 8.2 0.88 9.5 5.7 1.5 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase Pectate_lyase_3 PF12708.2 EGO51394.1 - 9e-82 274.5 14.2 4.3e-67 226.5 4.7 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EGO51394.1 - 3e-07 29.7 0.5 0.014 14.8 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase RNase_H PF00075.19 EGO51401.1 - 0.006 16.9 0.0 0.037 14.3 0.0 2.1 2 0 0 2 2 2 1 RNase H tRNA-synt_1e PF01406.14 EGO51404.1 - 0.082 12.0 1.5 10 5.1 0.1 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain RNase_H PF00075.19 EGO51405.1 - 0.00031 21.0 0.0 0.00057 20.2 0.0 1.4 1 0 0 1 1 1 1 RNase H VTC PF09359.5 EGO51407.1 - 1.9e-101 338.8 0.1 3.9e-101 337.8 0.0 1.6 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EGO51407.1 - 3.7e-22 79.4 21.0 2.3e-11 43.9 0.0 4.9 2 2 1 4 4 4 2 SPX domain DUF202 PF02656.10 EGO51407.1 - 5e-13 49.0 2.6 1.1e-12 48.0 1.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) TrmB PF01978.14 EGO51407.1 - 0.0012 18.5 1.1 0.021 14.4 0.1 2.9 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB DUF1469 PF07332.6 EGO51407.1 - 0.022 14.4 0.5 0.044 13.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Fe_dep_repress PF01325.14 EGO51407.1 - 0.066 13.1 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Ank_2 PF12796.2 EGO51408.1 - 6.8e-08 32.7 0.0 5.7e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGO51408.1 - 0.044 14.0 0.0 35 5.0 0.0 3.8 4 1 0 4 4 4 0 Ankyrin repeat Ank_5 PF13857.1 EGO51408.1 - 0.074 13.3 0.1 18 5.7 0.0 3.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) p450 PF00067.17 EGO51409.1 - 1.4e-47 162.2 0.0 1.8e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EGO51411.1 - 8e-85 285.0 12.6 9.1e-85 284.9 8.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO51411.1 - 7.1e-30 103.9 46.5 1.5e-27 96.2 15.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGO51411.1 - 6.9e-10 37.7 0.5 6.9e-10 37.7 0.4 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EGO51411.1 - 0.0025 16.3 0.8 0.0025 16.3 0.5 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein MutS_V PF00488.16 EGO51412.1 - 7.7e-78 261.1 0.0 1.6e-77 260.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGO51412.1 - 2.2e-36 125.5 1.7 3.5e-36 124.9 1.2 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EGO51412.1 - 5.3e-29 100.5 0.0 1.2e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EGO51412.1 - 7.1e-10 39.0 0.0 2e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EGO51412.1 - 4.6e-07 29.9 0.6 1.2e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 MutS family domain IV DUF1964 PF09244.5 EGO51412.1 - 0.095 13.0 0.1 0.45 10.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1964) Cys_Met_Meta_PP PF01053.15 EGO51414.1 - 8.5e-27 93.4 0.0 1.2e-20 73.1 0.0 2.6 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EGO51414.1 - 0.0009 18.2 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II AP_endonuc_2 PF01261.19 EGO51414.1 - 0.0089 15.3 0.0 0.78 8.9 0.0 2.6 2 0 0 2 2 2 2 Xylose isomerase-like TIM barrel AAA PF00004.24 EGO51415.1 - 6.7e-58 194.5 0.0 2.1e-43 147.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EGO51415.1 - 4.1e-28 97.2 0.0 8.3e-28 96.2 0.0 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EGO51415.1 - 5.7e-11 42.7 2.3 6.5e-05 22.9 0.0 3.9 2 1 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.9 EGO51415.1 - 6e-09 36.0 0.0 0.00014 21.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.7 EGO51415.1 - 6.1e-09 35.7 0.9 0.0002 21.0 0.0 4.4 4 0 0 4 4 4 1 NACHT domain AAA_22 PF13401.1 EGO51415.1 - 2.2e-06 27.8 0.9 0.055 13.6 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EGO51415.1 - 2.3e-06 27.5 0.1 0.063 13.1 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EGO51415.1 - 3.2e-06 27.9 0.5 0.16 12.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGO51415.1 - 5.2e-06 26.1 0.3 0.051 13.3 0.0 3.8 3 0 0 3 3 3 2 Part of AAA domain AAA_14 PF13173.1 EGO51415.1 - 7.2e-06 25.9 0.0 0.062 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGO51415.1 - 7.3e-06 25.7 0.1 0.038 13.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EGO51415.1 - 9.7e-06 25.9 0.3 0.013 15.7 0.0 3.3 3 1 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 EGO51415.1 - 1.2e-05 25.3 0.0 0.006 16.6 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain RuvB_N PF05496.7 EGO51415.1 - 2.3e-05 23.5 0.0 0.013 14.5 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 EGO51415.1 - 7e-05 22.0 0.0 0.16 11.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 EGO51415.1 - 0.00015 21.2 1.8 0.14 11.5 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 EGO51415.1 - 0.00044 20.2 0.2 0.18 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGO51415.1 - 0.00066 19.8 0.1 3.5 7.8 0.0 3.4 3 0 0 3 3 3 1 RNA helicase TIP49 PF06068.8 EGO51415.1 - 0.00066 18.4 0.0 0.9 8.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Sigma54_activat PF00158.21 EGO51415.1 - 0.001 18.6 0.4 0.22 11.0 0.0 3.4 4 0 0 4 4 3 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EGO51415.1 - 0.0011 18.1 0.3 0.69 9.0 0.0 3.0 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EGO51415.1 - 0.0012 18.2 5.0 2 7.7 0.1 4.2 2 2 1 4 4 4 1 AAA domain NB-ARC PF00931.17 EGO51415.1 - 0.0026 16.6 0.5 0.75 8.6 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain ABC_tran PF00005.22 EGO51415.1 - 0.0043 17.3 0.0 1.8 8.8 0.0 2.8 2 0 0 2 2 2 1 ABC transporter NTPase_1 PF03266.10 EGO51415.1 - 0.0067 16.1 0.1 0.14 11.8 0.0 2.3 2 0 0 2 2 2 1 NTPase Viral_helicase1 PF01443.13 EGO51415.1 - 0.0099 15.4 0.0 3.7 7.0 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 EGO51415.1 - 0.01 15.4 0.8 6 6.3 0.1 2.8 3 0 0 3 3 2 0 AAA domain KaiC PF06745.8 EGO51415.1 - 0.011 14.9 0.1 2.7 7.0 0.0 2.5 2 0 0 2 2 2 0 KaiC DUF2075 PF09848.4 EGO51415.1 - 0.019 13.9 0.2 7.1 5.5 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 EGO51415.1 - 0.022 14.3 0.1 0.65 9.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 EGO51415.1 - 0.036 13.0 0.1 6.4 5.6 0.0 2.6 1 1 1 2 2 2 0 KAP family P-loop domain AAA_29 PF13555.1 EGO51415.1 - 0.038 13.5 2.3 0.24 10.9 0.1 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain Cytidylate_kin2 PF13189.1 EGO51415.1 - 0.041 13.7 0.6 2.1 8.1 0.0 3.2 3 1 0 3 3 3 0 Cytidylate kinase-like family APS_kinase PF01583.15 EGO51415.1 - 0.046 13.3 0.4 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF815 PF05673.8 EGO51415.1 - 0.086 11.7 0.0 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SKI PF01202.17 EGO51415.1 - 0.091 12.6 0.2 5.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase Arch_ATPase PF01637.13 EGO51415.1 - 0.13 11.9 0.1 21 4.6 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase T2SE PF00437.15 EGO51415.1 - 0.13 11.1 2.9 1.7 7.5 0.1 3.1 3 0 0 3 3 3 0 Type II/IV secretion system protein CobU PF02283.11 EGO51415.1 - 0.15 11.4 1.4 0.21 10.9 0.0 2.1 2 0 0 2 2 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase PhoH PF02562.11 EGO51415.1 - 5.7 6.1 5.8 21 4.2 0.0 3.2 3 0 0 3 3 3 0 PhoH-like protein MCM PF00493.18 EGO51416.1 - 8.8e-135 448.7 0.0 1.3e-134 448.2 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGO51416.1 - 9.9e-27 93.8 1.7 7.5e-26 91.0 0.4 2.5 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGO51416.1 - 1.6e-07 30.7 0.0 1.2e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGO51416.1 - 8.2e-07 28.8 0.2 7.6e-06 25.6 0.0 2.8 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EGO51416.1 - 7.7e-06 26.2 0.3 4.4e-05 23.7 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGO51416.1 - 0.031 13.8 0.0 0.11 12.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.4 EGO51417.1 - 6.8e-102 340.5 0.0 9.4e-102 340.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 RRS1 PF04939.7 EGO51418.1 - 8.3e-58 194.4 0.7 9.6e-58 194.2 0.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.22 EGO51419.1 - 2.9e-28 98.3 0.0 5e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain NAM-associated PF14303.1 EGO51419.1 - 3.6 7.8 16.7 0.59 10.4 2.9 2.6 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Ribosomal_60s PF00428.14 EGO51420.1 - 0.16 12.3 3.4 0.36 11.2 2.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Prenyltrans PF00432.16 EGO51421.1 - 2e-53 177.5 10.1 2.5e-11 42.9 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGO51421.1 - 9.5e-38 129.0 0.1 1.4e-15 57.7 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGO51421.1 - 6.7e-12 45.3 0.0 1.7e-05 24.7 0.0 2.8 3 1 1 4 4 4 2 Prenyltransferase-like Nse5 PF08691.5 EGO51422.1 - 0.028 12.9 1.2 0.045 12.2 0.8 1.2 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 GLTT PF01744.15 EGO51422.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 GLTT repeat (6 copies) Complex1_LYR PF05347.10 EGO51423.1 - 4.1e-18 64.9 0.9 5.2e-18 64.6 0.6 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGO51423.1 - 2.1e-14 53.4 1.3 2.4e-14 53.2 0.9 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Vicilin_N PF04702.7 EGO51423.1 - 0.069 12.7 0.2 0.074 12.6 0.1 1.1 1 0 0 1 1 1 0 Vicilin N terminal region FAA_hydrolase PF01557.13 EGO51424.1 - 5.4e-62 209.0 0.0 7.4e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family BAH PF01426.13 EGO51427.1 - 1.3e-05 24.8 0.1 2.7e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 EGO51427.1 - 0.0013 18.4 1.8 0.0034 17.0 1.2 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EGO51427.1 - 0.028 14.5 0.2 0.069 13.2 0.1 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 EGO51427.1 - 0.051 13.5 0.2 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 RING-like domain 4HBT_3 PF13622.1 EGO51427.1 - 1.7 8.3 9.3 0.082 12.6 1.9 2.2 3 0 0 3 3 3 0 Thioesterase-like superfamily ATG22 PF11700.3 EGO51428.1 - 2.6e-195 649.4 13.5 3.2e-195 649.1 9.4 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF3602 PF12223.3 EGO51429.1 - 5e-13 49.2 12.6 1.1e-12 48.0 3.2 3.2 3 1 1 4 4 4 2 Protein of unknown function (DUF3602) HET PF06985.6 EGO51430.1 - 1.3e-05 25.3 0.2 0.00025 21.2 0.0 2.4 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) MamL-1 PF09596.5 EGO51430.1 - 0.072 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 MamL-1 domain DUF2401 PF10287.4 EGO51431.1 - 3.9e-69 232.7 0.0 6.6e-69 231.9 0.0 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EGO51431.1 - 3.8e-22 78.2 0.0 8.7e-22 77.0 0.0 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) XPG_N PF00752.12 EGO51432.1 - 3.4e-33 113.9 0.0 8.7e-33 112.6 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EGO51432.1 - 3.7e-26 91.0 0.0 7.9e-26 89.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 EGO51432.1 - 0.0049 16.3 8.7 0.0069 15.8 0.9 4.7 2 0 0 2 2 2 1 Ubiquitin interaction motif LSM PF01423.17 EGO51433.1 - 1.4e-08 34.1 0.0 1.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain SET PF00856.23 EGO51434.1 - 2.9e-21 76.4 0.1 2.9e-21 76.4 0.1 4.6 4 3 0 4 4 4 1 SET domain Pil1 PF13805.1 EGO51435.1 - 2.5e-148 492.5 0.8 8.1e-77 258.0 0.0 2.1 2 0 0 2 2 2 2 Eisosome component PIL1 Treacle PF03546.9 EGO51435.1 - 0.024 13.4 1.7 0.036 12.8 1.2 1.1 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle RRF PF01765.14 EGO51436.1 - 3.1e-21 75.5 0.5 3.8e-21 75.2 0.4 1.1 1 0 0 1 1 1 1 Ribosome recycling factor XH PF03469.9 EGO51436.1 - 0.083 12.5 5.2 0.13 11.8 3.6 1.3 1 0 0 1 1 1 0 XH domain HAUS6_N PF14661.1 EGO51436.1 - 0.21 10.9 7.0 0.3 10.4 4.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus IncA PF04156.9 EGO51436.1 - 9.7 5.7 8.0 14 5.1 5.5 1.2 1 0 0 1 1 1 0 IncA protein UPF0164 PF03687.8 EGO51437.1 - 0.024 13.1 0.2 0.033 12.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) WD40 PF00400.27 EGO51438.1 - 8.3e-29 98.4 13.8 2.3e-10 39.9 0.0 10.7 11 0 0 11 11 11 8 WD domain, G-beta repeat SUR7 PF06687.7 EGO51439.1 - 1.8e-39 135.5 10.8 2.1e-39 135.2 7.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4064 PF13273.1 EGO51439.1 - 0.61 10.2 10.6 0.034 14.2 2.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) 5TM-5TMR_LYT PF07694.7 EGO51439.1 - 4.6 6.5 17.5 0.098 11.9 6.3 2.2 2 1 1 3 3 3 0 5TMR of 5TMR-LYT Metallophos PF00149.23 EGO51441.1 - 6.6e-41 139.9 0.4 9.7e-41 139.3 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_3 PF00933.16 EGO51444.1 - 2e-88 296.2 0.0 2.8e-88 295.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO51444.1 - 1.3e-74 250.6 0.0 3.1e-73 246.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGO51444.1 - 1.4e-24 85.8 0.8 2.8e-24 84.8 0.6 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EGO51444.1 - 3.2e-22 78.7 0.0 5.2e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Glyco_hydro_18 PF00704.23 EGO51445.1 - 2.7e-43 148.7 4.9 4.6e-43 147.9 2.3 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Hce2 PF14856.1 EGO51445.1 - 1.3e-31 108.2 5.2 2.7e-31 107.3 1.2 3.3 3 0 0 3 3 3 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.15 EGO51445.1 - 2e-10 40.3 0.0 0.00057 19.7 0.0 2.9 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 EGO51445.1 - 0.00067 19.5 3.8 0.00067 19.5 2.6 4.0 3 0 0 3 3 3 1 Chitin recognition protein LysM PF01476.15 EGO51447.1 - 3e-14 52.6 0.0 5.7e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 LysM domain Dmrt1 PF12374.3 EGO51447.1 - 0.078 13.3 1.3 0.16 12.3 0.9 1.4 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 Metallophos PF00149.23 EGO51448.1 - 3.6e-23 82.0 2.0 6.3e-23 81.2 1.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1708 PF08101.6 EGO51449.1 - 8.1e-161 535.5 0.0 1.1e-160 535.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) UDG PF03167.14 EGO51450.1 - 6.1e-24 84.2 0.1 9.3e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily NESP55 PF06390.7 EGO51451.1 - 0.17 11.2 1.2 0.38 10.0 0.8 1.5 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Mito_carr PF00153.22 EGO51452.1 - 2e-60 200.4 2.4 2.1e-20 72.2 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Stomoxyn PF11585.3 EGO51452.1 - 0.22 11.3 1.7 11 5.9 0.4 2.8 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn PAF-AH_p_II PF03403.8 EGO51455.1 - 1.3e-54 184.9 0.0 2.7e-26 91.7 0.0 3.6 3 1 1 4 4 4 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EGO51455.1 - 2.2e-12 46.9 0.0 3e-11 43.2 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO51455.1 - 1.8e-08 34.5 0.0 5.6e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGO51455.1 - 2.4e-06 26.6 0.0 7.3e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EGO51455.1 - 3e-06 26.2 0.0 2.2e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 EGO51455.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase HsbA PF12296.3 EGO51456.1 - 0.0014 18.4 3.1 0.0072 16.1 1.1 2.4 2 1 1 3 3 3 1 Hydrophobic surface binding protein A Synaptonemal_3 PF15191.1 EGO51456.1 - 0.088 12.5 0.2 2.5 7.8 0.0 2.5 2 1 1 3 3 3 0 Synaptonemal complex central element protein 3 NAD_binding_10 PF13460.1 EGO51458.1 - 7.9e-08 32.5 0.0 3.4e-07 30.4 0.0 2.1 2 1 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EGO51458.1 - 0.039 13.1 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Glyco_transf_28 PF03033.15 EGO51459.1 - 1.5e-21 76.6 0.0 9.2e-21 74.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EGO51459.1 - 2.6e-07 29.5 0.0 4.9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EGO51459.1 - 0.00037 20.2 0.0 0.00085 19.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 EGO51459.1 - 0.0028 17.7 0.0 0.0074 16.4 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain Glyco_transf_22 PF03901.12 EGO51460.1 - 4.3e-45 154.4 14.1 5.9e-45 154.0 9.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family F_actin_cap_B PF01115.12 EGO51461.1 - 3.2e-108 360.5 0.0 3.8e-108 360.2 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit P3A PF08727.6 EGO51461.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Poliovirus 3A protein like Epimerase PF01370.16 EGO51463.1 - 2.3e-19 69.7 0.0 3.4e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGO51463.1 - 1.2e-08 34.2 0.0 1.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EGO51463.1 - 7.2e-08 32.5 0.0 3e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EGO51463.1 - 0.0011 18.9 0.0 0.0058 16.6 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGO51463.1 - 0.0067 15.1 0.0 0.038 12.7 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EGO51463.1 - 0.011 15.4 0.0 0.032 13.8 0.0 1.7 2 0 0 2 2 2 0 KR domain Saccharop_dh PF03435.13 EGO51463.1 - 0.011 14.7 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EGO51463.1 - 0.031 13.2 0.0 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Ldh_1_N PF00056.18 EGO51463.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain CBS PF00571.23 EGO51465.1 - 0.0031 17.2 0.0 0.77 9.6 0.0 2.7 2 1 1 3 3 3 2 CBS domain Mito_carr PF00153.22 EGO51466.1 - 3.5e-54 180.4 7.4 1.3e-19 69.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PNP_UDP_1 PF01048.15 EGO51467.1 - 0.00057 18.9 0.7 0.0028 16.6 0.5 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_12 PF13424.1 EGO51468.1 - 4.3e-37 125.9 4.1 7e-09 35.5 0.0 6.4 4 1 4 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.1 EGO51468.1 - 9.6e-29 98.4 4.8 6.8e-07 29.0 0.0 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGO51468.1 - 3e-11 43.6 3.4 0.0086 16.7 1.1 5.7 4 1 1 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGO51468.1 - 6.9e-08 31.7 0.0 1.2 9.1 0.1 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO51468.1 - 5.5e-07 29.8 0.9 0.19 12.1 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGO51468.1 - 5.7e-07 28.9 7.7 1.6 8.8 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGO51468.1 - 3.8e-06 26.4 0.0 0.0067 16.0 0.0 4.6 4 1 0 5 5 5 1 TPR repeat TPR_14 PF13428.1 EGO51468.1 - 1.4e-05 25.2 5.7 8.4 7.3 0.0 7.1 5 3 3 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.9 EGO51468.1 - 2.3e-05 24.4 0.4 6 7.6 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 EGO51468.1 - 3.9e-05 23.8 0.0 0.00019 21.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EGO51468.1 - 4.8e-05 22.3 0.0 0.00034 19.5 0.0 2.2 1 1 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.23 EGO51468.1 - 0.0001 21.7 0.6 20 5.0 0.0 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat Apc3 PF12895.2 EGO51468.1 - 0.0015 18.5 0.1 0.38 10.9 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 AAA_16 PF13191.1 EGO51468.1 - 0.0027 17.7 0.0 0.041 13.8 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Coatomer_E PF04733.9 EGO51468.1 - 0.0089 15.2 0.0 0.75 8.9 0.0 2.6 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_8 PF13181.1 EGO51468.1 - 0.016 14.9 0.1 51 3.9 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGO51468.1 - 0.035 14.5 0.4 91 3.8 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DNA_pol_B_thumb PF14791.1 EGO51471.1 - 3.2e-23 81.1 0.1 8.8e-23 79.7 0.1 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EGO51471.1 - 1.2e-21 76.8 0.0 3e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 EGO51471.1 - 6e-21 73.7 0.5 1.4e-20 72.5 0.1 1.8 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EGO51471.1 - 9.4e-18 64.1 0.0 4.7e-17 61.9 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 EGO51471.1 - 0.025 14.7 0.1 0.49 10.6 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EGO51471.1 - 0.042 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Mob1_phocein PF03637.12 EGO51472.1 - 6.5e-39 133.3 4.0 8e-22 77.7 0.1 2.1 2 0 0 2 2 2 2 Mob1/phocein family Methyltransf_31 PF13847.1 EGO51473.1 - 7.4e-14 51.6 0.0 1.4e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO51473.1 - 3.2e-11 42.8 0.0 5e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.11 EGO51473.1 - 1.3e-10 40.7 0.0 2e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 EGO51473.1 - 2.7e-10 40.8 0.0 8.7e-10 39.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO51473.1 - 7.7e-10 39.1 0.0 2.2e-09 37.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO51473.1 - 2.7e-09 37.0 0.0 5e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EGO51473.1 - 9e-08 31.1 0.1 1.4e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EGO51473.1 - 1.7e-06 28.3 0.0 1.1e-05 25.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO51473.1 - 2.2e-06 27.4 0.0 5.8e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EGO51473.1 - 7e-06 25.5 0.1 1.4e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EGO51473.1 - 7.8e-06 26.2 0.0 2e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGO51473.1 - 0.00019 21.4 0.0 0.00039 20.4 0.0 1.5 2 0 0 2 2 1 1 FtsJ-like methyltransferase CMAS PF02353.15 EGO51473.1 - 0.00023 20.3 0.0 0.00034 19.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EGO51473.1 - 0.0032 17.0 0.2 0.0049 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 EGO51473.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.8 EGO51473.1 - 0.013 14.8 0.3 0.026 13.8 0.1 1.5 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_32 PF13679.1 EGO51473.1 - 0.014 15.1 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 EGO51473.1 - 0.019 14.5 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 EGO51473.1 - 0.026 13.5 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 EGO51473.1 - 0.032 13.4 0.4 0.1 11.7 0.3 1.9 1 1 0 1 1 1 0 Tellurite resistance protein TehB Cons_hypoth95 PF03602.10 EGO51473.1 - 0.041 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PGM_PMM_I PF02878.11 EGO51474.1 - 9.7e-18 63.9 0.1 1.4e-07 31.1 0.0 2.7 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EGO51474.1 - 9.4e-12 45.1 0.1 6.5e-11 42.4 0.0 2.6 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EGO51474.1 - 1.1e-10 41.3 0.3 3.5e-10 39.7 0.2 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EGO51474.1 - 0.0078 16.2 0.0 0.024 14.6 0.0 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III ERCC4 PF02732.10 EGO51475.1 - 3.2e-33 114.4 0.1 5.4e-33 113.7 0.1 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 EGO51475.1 - 0.0067 16.5 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain Lum_binding PF00677.12 EGO51476.1 - 5.1e-39 132.0 0.4 1e-18 67.0 0.0 2.9 2 1 0 2 2 2 2 Lumazine binding domain Dehydrin PF00257.14 EGO51476.1 - 0.008 16.5 0.4 0.06 13.6 0.0 2.0 2 0 0 2 2 2 1 Dehydrin Glyco_transf_17 PF04724.8 EGO51477.1 - 8.3e-24 84.2 0.0 1.6e-13 50.3 0.0 3.1 2 1 1 3 3 3 3 Glycosyltransferase family 17 CFEM PF05730.6 EGO51478.1 - 3.4e-13 49.1 11.5 5.5e-13 48.5 8.0 1.3 1 0 0 1 1 1 1 CFEM domain Peptidase_C15 PF01470.12 EGO51479.1 - 7.9e-13 48.7 0.0 0.0019 18.0 0.0 3.1 3 0 0 3 3 3 3 Pyroglutamyl peptidase Oxidored_FMN PF00724.15 EGO51480.1 - 1.2e-72 244.7 0.0 1.5e-71 241.1 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family tRNA-synt_1g PF09334.6 EGO51481.1 - 1.2e-132 442.2 0.0 6.4e-132 439.9 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGO51481.1 - 3e-07 28.8 5.7 0.0017 16.4 0.0 4.1 4 1 1 5 5 5 3 tRNA synthetases class I (I, L, M and V) DUF2421 PF10334.4 EGO51481.1 - 0.0055 16.3 0.0 0.015 14.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2421) GBP_C PF02841.9 EGO51481.1 - 4.4 6.3 16.0 0.91 8.6 0.1 2.1 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain BTB PF00651.26 EGO51482.1 - 1.1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Flu_NP PF00506.13 EGO51483.1 - 0.0035 15.8 0.0 0.0045 15.5 0.0 1.1 1 0 0 1 1 1 1 Influenza virus nucleoprotein Fz PF01392.17 EGO51483.1 - 0.02 15.2 1.9 0.028 14.7 1.3 1.1 1 0 0 1 1 1 0 Fz domain IGFBP PF00219.13 EGO51483.1 - 0.26 11.8 5.6 0.43 11.1 3.9 1.3 1 0 0 1 1 1 0 Insulin-like growth factor binding protein HET PF06985.6 EGO51484.1 - 2.6e-20 73.0 0.3 6.5e-20 71.7 0.2 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mg_trans_NIPA PF05653.9 EGO51486.1 - 7.3e-15 54.6 7.2 1.1e-14 54.1 5.0 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EGO51486.1 - 0.00022 21.2 16.1 0.00093 19.2 0.3 2.7 2 1 0 2 2 2 2 EamA-like transporter family vATP-synt_E PF01991.13 EGO51487.1 - 7.1e-69 231.0 2.6 8.1e-69 230.8 1.8 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Gly-zipper_OmpA PF13436.1 EGO51488.1 - 0.54 9.9 3.9 1 9.0 2.7 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain E1-E2_ATPase PF00122.15 EGO51489.1 - 9.4e-17 60.8 0.1 7.1e-16 57.9 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EGO51489.1 - 6.4e-12 45.2 0.0 1.7e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGO51489.1 - 8.5e-12 45.6 0.0 2.3e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO51489.1 - 7.8e-10 39.5 2.5 6.9e-08 33.1 1.7 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGO51489.1 - 0.0079 15.7 0.5 0.022 14.3 0.4 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGO51489.1 - 0.066 13.4 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Aldedh PF00171.17 EGO51490.1 - 3.7e-117 391.4 0.0 4.4e-117 391.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Protocadherin PF08374.6 EGO51491.1 - 0.12 11.9 0.7 0.13 11.8 0.5 1.1 1 0 0 1 1 1 0 Protocadherin Zn_ribbon_recom PF13408.1 EGO51491.1 - 0.28 11.4 2.6 0.36 11.1 1.8 1.2 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain ERCC4 PF02732.10 EGO51492.1 - 1.7e-26 92.7 0.0 3.7e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.1 EGO51492.1 - 0.00045 20.3 0.1 0.0012 18.9 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF2316 PF10078.4 EGO51492.1 - 0.067 13.1 0.1 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) WH1 PF00568.18 EGO51494.1 - 2.5e-27 94.8 0.1 3.4e-27 94.3 0.1 1.2 1 0 0 1 1 1 1 WH1 domain eIF-1a PF01176.14 EGO51495.1 - 4e-28 96.6 0.3 5.6e-28 96.1 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 PTCB-BRCT PF12738.2 EGO51497.1 - 2.4e-11 43.3 0.0 5.1e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EGO51497.1 - 2.3e-09 37.2 0.0 4.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 EGO51497.1 - 0.00027 21.0 1.0 0.00085 19.4 0.0 2.3 2 1 0 2 2 2 1 Fibronectin type III domain DUF3006 PF11213.3 EGO51497.1 - 0.022 14.4 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) adh_short PF00106.20 EGO51498.1 - 4.3e-06 26.7 0.0 1.1e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO51498.1 - 0.043 13.5 0.0 0.089 12.5 0.0 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO51498.1 - 0.082 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 KR domain Tetraspannin PF00335.15 EGO51500.1 - 7.9e-06 25.3 11.5 1.3e-05 24.5 8.0 1.5 1 1 0 1 1 1 1 Tetraspanin family Hum_adeno_E3A PF05393.6 EGO51500.1 - 0.029 14.0 1.6 1.9 8.1 0.2 2.4 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein ExbD PF02472.11 EGO51500.1 - 0.18 11.8 0.5 0.34 10.9 0.4 1.5 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR DUF4064 PF13273.1 EGO51500.1 - 0.57 10.3 8.0 1.2 9.3 4.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Mito_fiss_reg PF05308.6 EGO51502.1 - 0.15 11.4 4.3 0.079 12.3 1.8 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator SRF-TF PF00319.13 EGO51503.1 - 8.7e-24 82.5 0.4 1.2e-23 82.0 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3246 PF11596.3 EGO51503.1 - 0.064 12.5 0.3 0.088 12.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CDC45 PF02724.9 EGO51503.1 - 0.16 9.9 0.1 0.21 9.5 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TetR_C_8 PF14278.1 EGO51504.1 - 0.12 12.8 0.8 2.9 8.3 0.0 2.7 3 0 0 3 3 3 0 Transcriptional regulator C-terminal region Ctr PF04145.10 EGO51505.1 - 1.6e-31 109.2 1.2 1.9e-31 109.0 0.8 1.0 1 0 0 1 1 1 1 Ctr copper transporter family zf-C2H2 PF00096.21 EGO51507.1 - 1.5e-10 40.8 10.6 3.2e-05 23.9 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO51507.1 - 8e-07 29.0 13.8 4.1e-06 26.7 0.8 2.9 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO51507.1 - 1.8e-05 24.7 14.3 0.0012 19.0 0.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EGO51507.1 - 0.0098 16.0 1.7 0.0098 16.0 1.2 2.8 3 0 0 3 3 3 1 C2H2-type zinc-finger domain SprT-like PF10263.4 EGO51507.1 - 0.026 14.2 0.7 0.041 13.5 0.5 1.4 1 0 0 1 1 1 0 SprT-like family zf-C2H2_6 PF13912.1 EGO51507.1 - 0.04 13.8 4.3 0.45 10.4 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger BolA PF01722.13 EGO51507.1 - 0.081 12.8 0.1 3.3 7.7 0.0 2.3 2 0 0 2 2 2 0 BolA-like protein zf-CHY PF05495.7 EGO51507.1 - 0.14 12.2 1.8 0.26 11.4 1.2 1.4 1 0 0 1 1 1 0 CHY zinc finger DUF605 PF04652.11 EGO51507.1 - 7.1 5.9 11.2 9.7 5.4 7.7 1.2 1 0 0 1 1 1 0 Vta1 like Malate_synthase PF01274.17 EGO51508.1 - 4.3e-240 797.1 0.0 4.8e-240 797.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Lyase_1 PF00206.15 EGO51509.1 - 9.3e-111 369.9 0.0 1.3e-110 369.4 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EGO51509.1 - 5.4e-23 80.8 0.0 5.4e-23 80.8 0.0 2.5 3 0 0 3 3 3 1 Fumarase C C-terminus AKNA PF12443.3 EGO51509.1 - 0.079 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor SHOCT PF09851.4 EGO51509.1 - 0.56 9.7 2.6 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Short C-terminal domain Pkinase PF00069.20 EGO51510.1 - 3.2e-77 259.1 0.1 5.1e-77 258.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO51510.1 - 1.3e-39 135.8 0.5 1.5e-36 125.8 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGO51510.1 - 1.8e-05 23.8 0.0 5.3e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 EGO51510.1 - 0.00021 20.9 0.1 0.00044 19.8 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EGO51510.1 - 0.00033 19.7 0.8 0.0017 17.4 0.1 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO51510.1 - 0.0016 18.2 0.0 0.0052 16.5 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family SMC_N PF02463.14 EGO51511.1 - 9.8e-24 83.7 0.0 1.6e-23 83.1 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGO51511.1 - 5.8e-11 43.0 20.3 5.8e-11 43.0 14.1 5.3 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EGO51511.1 - 8.8e-05 22.6 0.0 0.0011 19.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EGO51511.1 - 0.0039 17.3 0.1 0.04 14.1 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EGO51511.1 - 0.013 15.0 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.1 EGO51511.1 - 0.039 13.0 0.0 0.039 13.0 0.0 2.6 2 2 0 2 2 2 0 AAA ATPase domain Reo_sigmaC PF04582.7 EGO51511.1 - 5.7 6.0 10.7 3.6 6.6 0.3 3.9 2 2 1 3 3 3 0 Reovirus sigma C capsid protein GATA PF00320.22 EGO51515.1 - 7.8e-17 60.3 1.5 1.6e-16 59.3 1.1 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EGO51515.1 - 7.7e-14 50.9 0.7 1.5e-13 50.0 0.5 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MFS_1 PF07690.11 EGO51516.1 - 3.4e-26 91.7 45.4 1.4e-24 86.4 25.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Wbp11 PF09429.5 EGO51517.1 - 5.1e-17 61.6 15.8 6.6e-13 48.4 5.9 3.1 3 1 1 4 4 4 2 WW domain binding protein 11 Lipoprotein_7 PF01540.11 EGO51517.1 - 0.0013 17.8 2.6 0.0019 17.3 1.8 1.2 1 0 0 1 1 1 1 Adhesin lipoprotein Tup_N PF08581.5 EGO51517.1 - 0.016 15.4 2.8 0.043 14.0 1.9 1.8 1 0 0 1 1 1 0 Tup N-terminal HemX PF04375.9 EGO51517.1 - 0.025 13.1 3.3 0.042 12.4 2.3 1.3 1 0 0 1 1 1 0 HemX DUF3450 PF11932.3 EGO51517.1 - 0.93 8.7 8.1 1.6 7.9 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Pkinase PF00069.20 EGO51518.1 - 6e-58 196.0 0.0 3.3e-57 193.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO51518.1 - 3.5e-28 98.4 0.3 5.6e-20 71.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EGO51518.1 - 3.5e-06 27.4 0.1 8.4e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGO51518.1 - 0.00048 19.1 0.3 0.0022 16.9 0.0 2.1 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EGO51518.1 - 0.0051 16.5 0.7 0.086 12.5 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO51518.1 - 0.03 13.3 0.1 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family CFEM PF05730.6 EGO51519.1 - 0.086 12.6 6.8 0.17 11.7 4.7 1.5 1 0 0 1 1 1 0 CFEM domain HET PF06985.6 EGO51520.1 - 1.3e-27 96.6 0.5 2.5e-27 95.7 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) G-alpha PF00503.15 EGO51521.1 - 0.0046 15.6 3.4 0.0067 15.1 2.3 1.2 1 0 0 1 1 1 1 G-protein alpha subunit CAF-1_p150 PF11600.3 EGO51521.1 - 0.032 13.6 21.2 0.042 13.2 14.7 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal YcbB PF08664.5 EGO51521.1 - 0.075 12.8 5.6 0.16 11.7 3.9 1.6 1 0 0 1 1 1 0 YcbB domain DEAD PF00270.24 EGO51524.1 - 3.9e-38 130.5 0.1 6.3e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO51524.1 - 3.9e-24 84.2 0.0 6.1e-23 80.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO51524.1 - 8.5e-07 28.9 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EGO51524.1 - 0.056 12.5 0.0 0.41 9.6 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Rpr2 PF04032.11 EGO51525.1 - 7.2e-22 77.0 0.6 1.6e-21 75.9 0.4 1.6 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-BED PF02892.10 EGO51525.1 - 0.09 12.5 1.4 0.97 9.2 0.1 2.3 2 0 0 2 2 2 0 BED zinc finger DASH_Hsk3 PF08227.6 EGO51526.1 - 5.1e-21 74.5 3.8 5.1e-21 74.5 2.6 1.6 2 0 0 2 2 2 1 DASH complex subunit Hsk3 like FlxA PF14282.1 EGO51526.1 - 4.4 7.2 9.3 0.093 12.6 0.6 2.0 2 0 0 2 2 2 0 FlxA-like protein Secretin_N_2 PF07655.8 EGO51526.1 - 6.2 7.2 12.3 0.16 12.3 3.3 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain ApbA_C PF08546.6 EGO51527.1 - 1.5e-24 86.3 0.0 2.4e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EGO51527.1 - 2.4e-24 85.5 0.0 3.6e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Cyclin PF08613.6 EGO51533.1 - 8.3e-18 65.2 0.7 2.8e-17 63.5 0.0 2.1 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EGO51533.1 - 0.0019 17.7 0.1 0.0046 16.5 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain SOG2 PF10428.4 EGO51535.1 - 4.3e-112 375.0 0.0 4.3e-112 375.0 0.0 3.0 3 1 0 3 3 3 1 RAM signalling pathway protein Syntaxin-6_N PF09177.6 EGO51535.1 - 0.061 13.7 0.0 0.6 10.5 0.0 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Pyrid_oxidase_2 PF13883.1 EGO51536.1 - 3.9e-41 140.6 4.2 4.3e-40 137.2 2.9 2.3 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Zip PF02535.17 EGO51536.1 - 2.7 6.9 12.7 5.9 5.8 5.8 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Ribosomal_S30 PF04758.9 EGO51537.1 - 6.9e-30 102.5 9.3 8.2e-30 102.3 6.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 DFP PF04127.10 EGO51538.1 - 3.9e-13 49.4 0.0 8.9e-05 22.1 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein CorA PF01544.13 EGO51539.1 - 2.8e-14 52.8 0.8 4.8e-14 52.0 0.5 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4203 PF13886.1 EGO51539.1 - 0.23 10.9 2.4 0.32 10.4 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) F-box-like PF12937.2 EGO51540.1 - 0.032 13.9 0.1 0.079 12.6 0.1 1.7 1 0 0 1 1 1 0 F-box-like DEAD PF00270.24 EGO51541.1 - 1.1e-43 148.6 0.0 1.7e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO51541.1 - 2.2e-22 78.6 1.7 3e-22 78.2 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGO51541.1 - 2.9e-05 23.0 0.0 4.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 EGO51541.1 - 0.014 14.7 0.0 0.97 8.6 0.0 2.1 2 0 0 2 2 2 0 SecA DEAD-like domain ResIII PF04851.10 EGO51541.1 - 0.039 13.7 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ipi1_N PF12333.3 EGO51542.1 - 7.7e-30 102.8 0.0 2.4e-29 101.2 0.0 1.9 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.1 EGO51542.1 - 0.017 15.4 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats Robl_LC7 PF03259.12 EGO51543.1 - 2.7e-11 42.8 0.1 4.1e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 Roadblock/LC7 domain HOOK PF05622.7 EGO51544.1 - 0.45 8.2 0.1 0.64 7.7 0.1 1.1 1 0 0 1 1 1 0 HOOK protein MFS_1 PF07690.11 EGO51545.1 - 5.2e-41 140.5 30.4 1.7e-36 125.7 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO51545.1 - 1.8e-08 33.4 7.9 3.5e-08 32.4 5.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EGO51545.1 - 0.038 12.0 0.3 2.1 6.2 0.2 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family RNA_pol_Rpc4 PF05132.9 EGO51545.1 - 0.05 13.5 0.2 0.095 12.6 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 CENP-O PF09496.5 EGO51547.1 - 3.5e-21 75.2 0.0 1e-20 73.7 0.0 1.8 1 1 0 1 1 1 1 Cenp-O kinetochore centromere component SUZ PF12752.2 EGO51547.1 - 1.8 9.1 8.2 0.2 12.1 1.8 2.3 2 0 0 2 2 2 0 SUZ domain Acatn PF13000.2 EGO51548.1 - 1.3e-149 499.2 25.7 2.6e-76 257.3 5.5 3.0 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 BphX PF06139.7 EGO51548.1 - 0.0029 17.1 0.2 0.18 11.4 0.1 2.8 2 0 0 2 2 2 1 BphX-like Amidase PF01425.16 EGO51549.1 - 3.5e-77 260.1 0.1 4.4e-77 259.8 0.1 1.1 1 0 0 1 1 1 1 Amidase p450 PF00067.17 EGO51550.1 - 3.5e-35 121.4 0.3 3.4e-20 72.0 0.0 3.1 2 1 1 3 3 3 3 Cytochrome P450 PAM2 PF07145.10 EGO51551.1 - 7.6 6.2 13.1 0.11 12.0 0.6 3.8 4 0 0 4 4 4 0 Ataxin-2 C-terminal region Mid2 PF04478.7 EGO51552.1 - 9.2e-06 25.1 3.6 9.2e-06 25.1 2.5 2.1 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 EGO51552.1 - 0.098 11.9 0.5 0.32 10.3 0.4 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TFIIA PF03153.8 EGO51552.1 - 0.14 12.0 6.8 0.17 11.7 4.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_18 PF00704.23 EGO51553.1 - 1.2e-09 38.1 0.1 1.8e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Myb_DNA-binding PF00249.26 EGO51555.1 - 3.5e-11 42.9 0.6 4.4e-06 26.6 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGO51555.1 - 5.1e-10 39.3 0.1 0.00029 20.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain ATG_C PF09333.6 EGO51555.1 - 0.0024 17.9 0.4 0.45 10.7 0.1 2.5 2 0 0 2 2 2 2 ATG C terminal domain Ribosomal_S4e PF00900.15 EGO51556.1 - 4.6e-32 109.5 0.6 9.3e-32 108.5 0.4 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EGO51556.1 - 2.5e-19 68.8 3.8 5.5e-19 67.7 2.6 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EGO51556.1 - 5.4e-06 25.7 0.0 1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EGO51556.1 - 0.00011 21.7 1.6 0.00011 21.7 1.1 2.9 3 0 0 3 3 3 1 KOW motif FAD-oxidase_C PF02913.14 EGO51558.1 - 3e-59 200.3 0.1 4.9e-59 199.6 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGO51558.1 - 2.5e-34 117.7 0.0 6.1e-34 116.4 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 EGO51558.1 - 0.058 11.8 0.0 0.096 11.1 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) RdRP PF05183.7 EGO51559.1 - 1.8e-176 588.2 0.0 2.3e-176 587.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 EGO51559.1 - 0.0029 17.1 0.0 0.0065 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO51559.1 - 0.017 15.1 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Apc15p PF05841.6 EGO51559.1 - 1 10.1 6.0 2.9 8.6 2.0 2.5 2 0 0 2 2 2 0 Apc15p protein PRCC PF10253.4 EGO51562.1 - 0.89 10.2 9.0 1.4 9.5 6.2 1.6 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Pex14_N PF04695.8 EGO51562.1 - 2.3 8.2 10.2 5.3 7.1 7.0 1.6 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region 2OG-FeII_Oxy_3 PF13640.1 EGO51563.1 - 5.1e-13 49.3 0.0 7.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EGO51563.1 - 2.2e-07 30.3 0.0 4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGO51563.1 - 1.9e-05 24.8 0.0 4.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PI-PLC-X PF00388.14 EGO51564.1 - 1e-59 200.1 0.1 7.4e-59 197.3 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EGO51564.1 - 1.2e-34 118.8 0.0 2.3e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PAXIP1_C PF15364.1 EGO51565.1 - 0.0026 17.6 1.2 0.004 17.0 0.8 1.3 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein NinG PF05766.7 EGO51565.1 - 0.011 15.5 2.2 0.015 15.0 1.5 1.2 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein FimP PF09766.4 EGO51565.1 - 0.013 14.5 6.0 0.017 14.2 4.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein Zip PF02535.17 EGO51565.1 - 0.048 12.6 0.8 0.054 12.4 0.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Suf PF05843.9 EGO51565.1 - 0.19 11.4 5.1 0.2 11.3 3.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4175 PF13779.1 EGO51565.1 - 0.2 9.3 11.0 0.24 9.0 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PNRC PF15365.1 EGO51565.1 - 0.22 11.5 3.7 0.42 10.6 2.6 1.5 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator PAT1 PF09770.4 EGO51565.1 - 0.93 7.6 18.5 1.1 7.4 12.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.8 EGO51565.1 - 1 8.1 22.6 1.3 7.7 15.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Med3 PF11593.3 EGO51565.1 - 1.1 8.4 13.3 1.6 7.8 9.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal vMSA PF00695.14 EGO51565.1 - 1.6 7.8 7.0 2.3 7.3 4.8 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF3154 PF11351.3 EGO51565.1 - 4.1 7.1 5.2 43 3.8 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) zf-C2H2 PF00096.21 EGO51566.1 - 3.2e-09 36.5 11.3 0.00034 20.7 0.9 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 EGO51566.1 - 7.6e-08 31.5 0.8 1.4e-07 30.6 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO51566.1 - 7e-06 25.8 9.7 7e-06 25.8 6.7 2.2 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EGO51566.1 - 0.0001 22.3 10.7 0.00057 20.0 0.8 3.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGO51566.1 - 0.00098 19.3 3.3 0.00098 19.3 2.3 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EGO51566.1 - 0.15 12.2 5.4 0.88 9.7 0.6 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGO51566.1 - 0.98 9.4 5.6 9.3 6.3 0.5 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Cupin_2 PF07883.6 EGO51567.1 - 0.0089 15.5 0.6 0.012 15.1 0.4 1.2 1 0 0 1 1 1 1 Cupin domain CFEM PF05730.6 EGO51569.1 - 1.9e-06 27.6 7.9 2.7e-06 27.0 5.5 1.2 1 0 0 1 1 1 1 CFEM domain Ovate PF04844.8 EGO51569.1 - 0.45 10.3 0.0 0.65 9.8 0.0 1.1 1 0 0 1 1 1 0 Transcriptional repressor, ovate CMS1 PF14617.1 EGO51570.1 - 1.5e-112 374.7 4.1 1.7e-112 374.5 2.8 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EGO51570.1 - 1.3e-07 31.2 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase PQ-loop PF04193.9 EGO51571.1 - 6.9e-19 67.1 9.0 4.7e-18 64.4 0.9 2.8 2 1 1 3 3 3 2 PQ loop repeat Ras PF00071.17 EGO51572.1 - 2.6e-51 173.2 0.0 3e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO51572.1 - 3.5e-19 69.4 0.0 7.2e-19 68.4 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGO51572.1 - 4.4e-09 35.8 0.0 5.4e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGO51572.1 - 2.8e-07 30.1 0.3 2.1e-06 27.3 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGO51572.1 - 0.00022 21.1 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGO51572.1 - 0.017 15.3 0.2 0.37 10.9 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA PF00004.24 EGO51572.1 - 0.055 13.6 0.3 0.15 12.2 0.2 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGO51572.1 - 0.098 12.6 0.8 1.6 8.6 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 EGO51572.1 - 0.1 11.2 0.0 5 5.7 0.0 2.3 2 1 0 2 2 2 0 G-protein alpha subunit Septin PF00735.13 EGO51572.1 - 0.11 11.5 0.0 0.61 9.0 0.0 1.9 2 0 0 2 2 2 0 Septin EzrA PF06160.7 EGO51574.1 - 0.25 9.4 0.1 8.4 4.4 0.0 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA P12 PF12669.2 EGO51575.1 - 0.022 14.9 1.2 0.12 12.5 0.2 2.5 2 0 0 2 2 2 0 Virus attachment protein p12 family CytB6-F_Fe-S PF08802.5 EGO51575.1 - 0.11 12.4 0.3 0.11 12.4 0.2 2.1 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Adeno_E3_CR2 PF02439.10 EGO51575.1 - 0.47 10.0 1.6 1.2 8.7 1.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ycf1 PF05758.7 EGO51575.1 - 0.56 7.8 3.3 0.69 7.5 2.3 1.1 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 EGO51575.1 - 0.92 7.4 11.8 1.4 6.8 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SURF1 PF02104.10 EGO51577.1 - 1.1e-64 218.1 0.0 1.5e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T PF15511.1 EGO51578.1 - 2.7e-114 382.6 19.1 3.3e-114 382.3 13.2 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EGO51578.1 - 7.9e-08 32.3 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGO51578.1 - 0.00011 22.1 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGO51578.1 - 0.00016 21.7 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Ras PF00071.17 EGO51579.1 - 1.8e-52 176.9 0.0 2.1e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO51579.1 - 4.9e-17 62.5 0.0 7.3e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO51579.1 - 9.9e-07 28.1 0.0 1.5e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.17 EGO51580.1 - 1.3e-11 43.9 0.0 3.3e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO51580.1 - 2.1e-10 40.4 0.0 3.9e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SET PF00856.23 EGO51580.1 - 0.25 11.6 8.3 7.6 6.8 3.6 2.2 2 0 0 2 2 2 0 SET domain DUF262 PF03235.9 EGO51580.1 - 5.2 6.9 14.0 16 5.3 7.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF262 UPF0560 PF10577.4 EGO51580.1 - 7.5 4.6 21.2 11 4.1 14.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CAF-1_p150 PF11600.3 EGO51580.1 - 9.2 5.5 73.4 1.5 8.1 3.6 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SET PF00856.23 EGO51581.1 - 8.2e-27 94.4 0.0 5.1e-26 91.9 0.0 2.1 2 0 0 2 2 2 1 SET domain Coq4 PF05019.8 EGO51582.1 - 8.8e-96 319.0 0.0 1.2e-95 318.6 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.15 EGO51583.1 - 2.8e-35 120.5 3.4 3.6e-35 120.1 2.4 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 EGO51583.1 - 0.038 14.2 1.3 0.053 13.7 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) RelB_N PF12910.2 EGO51583.1 - 0.11 11.9 0.1 0.24 10.8 0.1 1.5 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin stability system N-terminal ApbA PF02558.11 EGO51584.1 - 9.5e-30 103.0 0.0 1.4e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EGO51584.1 - 5.5e-12 45.7 0.0 9e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Sas10_Utp3 PF04000.10 EGO51585.1 - 6e-16 58.4 0.2 6e-16 58.4 0.1 1.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF2076 PF09849.4 EGO51585.1 - 0.0014 18.7 27.7 0.0085 16.1 19.2 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EGO51585.1 - 0.0045 16.8 5.7 0.0071 16.2 3.9 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EGO51585.1 - 0.043 13.9 1.3 0.072 13.2 0.0 1.9 2 0 0 2 2 2 0 GCK domain RF-1 PF00472.15 EGO51585.1 - 0.22 11.3 4.9 0.12 12.1 1.6 1.9 2 0 0 2 2 2 0 RF-1 domain UBX PF00789.15 EGO51586.1 - 7.4e-13 48.3 0.0 1.4e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 EGO51586.1 - 0.0027 17.6 0.0 0.15 12.0 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin-like CDC27 PF09507.5 EGO51586.1 - 0.017 14.4 27.6 0.024 13.8 19.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hom_end_hint PF05203.11 EGO51586.1 - 0.033 13.9 0.5 0.048 13.3 0.4 1.4 1 0 0 1 1 1 0 Hom_end-associated Hint CAF-1_p150 PF11600.3 EGO51586.1 - 0.5 9.7 29.3 1.4 8.2 20.3 1.8 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2763 PF10961.3 EGO51586.1 - 1.3 9.4 6.8 0.79 10.1 2.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2763) RRM_6 PF14259.1 EGO51587.1 - 6.9e-08 32.3 0.0 1.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO51587.1 - 0.00019 21.0 0.0 0.00036 20.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO51587.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EGO51588.1 - 1.3e-25 88.2 8.7 5.7e-10 38.6 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_3 PF13570.1 EGO51588.1 - 0.016 15.4 0.3 5.7 7.3 0.0 2.9 2 0 0 2 2 2 0 PQQ-like domain Cytochrom_D1 PF02239.11 EGO51588.1 - 0.03 12.6 0.2 13 3.9 0.0 3.1 3 0 0 3 3 3 0 Cytochrome D1 heme domain PD40 PF07676.7 EGO51588.1 - 0.049 13.3 1.0 1.1 9.0 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Metallophos PF00149.23 EGO51589.1 - 3e-12 46.3 0.0 2.5e-10 40.0 0.0 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGO51589.1 - 5.4e-10 39.3 0.0 1e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF3283 PF11686.3 EGO51589.1 - 0.13 12.0 0.6 0.26 11.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) Myc_N PF01056.13 EGO51589.1 - 0.15 11.1 4.9 0.44 9.6 0.1 2.8 3 0 0 3 3 3 0 Myc amino-terminal region Nucleoplasmin PF03066.10 EGO51589.1 - 2.7 7.5 14.4 0.47 9.9 0.4 3.1 3 0 0 3 3 3 0 Nucleoplasmin DUF4611 PF15387.1 EGO51589.1 - 9.7 6.4 15.9 3.6 7.7 0.8 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) ThiC-associated PF13667.1 EGO51590.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 ThiC-associated domain Pet191_N PF10203.4 EGO51591.1 - 9.2e-28 96.0 3.1 1.2e-27 95.6 2.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EGO51591.1 - 0.22 11.3 3.0 4.7 7.0 0.4 2.4 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Abhydro_lipase PF04083.11 EGO51592.1 - 9.2e-23 79.3 0.1 1.7e-22 78.5 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EGO51592.1 - 2.9e-17 63.0 0.2 5.8e-17 62.0 0.2 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGO51592.1 - 1.4e-05 25.0 0.0 3.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGO51592.1 - 0.0071 15.8 0.1 1.7 7.9 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Ank_5 PF13857.1 EGO51594.1 - 1.7e-07 31.2 0.1 4.7e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EGO51594.1 - 0.00031 20.4 0.2 0.0016 18.1 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EGO51594.1 - 0.005 17.1 0.0 0.036 14.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGO51594.1 - 0.014 15.5 0.0 0.23 11.8 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.1 EGO51594.1 - 0.13 12.8 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) AKAP95 PF04988.7 EGO51594.1 - 2.4 7.8 5.8 0.15 11.7 0.2 1.8 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) CFEM PF05730.6 EGO51596.1 - 0.00097 18.9 2.3 0.00097 18.9 1.6 3.3 3 0 0 3 3 3 1 CFEM domain GILT PF03227.11 EGO51597.1 - 0.12 12.1 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Gamma interferon inducible lysosomal thiol reductase (GILT) Zn_clus PF00172.13 EGO51598.1 - 2e-08 33.9 11.9 3.2e-08 33.3 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Annexin PF00191.15 EGO51599.1 - 3.3e-19 68.5 0.1 1.3e-05 24.9 0.0 4.5 4 0 0 4 4 4 4 Annexin DUF1180 PF06679.7 EGO51600.1 - 0.013 15.3 2.0 0.036 13.9 1.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) GPI2 PF06432.6 EGO51601.1 - 7.1e-121 402.8 0.2 8.7e-121 402.5 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Transaldolase PF00923.14 EGO51602.1 - 4.5e-94 314.7 0.2 5.2e-94 314.5 0.2 1.0 1 0 0 1 1 1 1 Transaldolase SNase PF00565.12 EGO51604.1 - 3.9e-71 236.1 4.4 5.5e-22 78.0 0.0 5.8 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EGO51604.1 - 3.3e-24 85.0 0.0 3e-23 81.9 0.0 2.3 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 EGO51604.1 - 4.8e-06 25.8 0.0 1.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Sod_Cu PF00080.15 EGO51605.1 - 2.1e-45 154.3 5.2 2.4e-45 154.1 3.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CNH PF00780.17 EGO51607.1 - 1.1e-70 238.2 0.0 1.7e-70 237.6 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EGO51607.1 - 5.4e-33 114.3 1.4 7.9e-33 113.8 0.9 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EGO51607.1 - 5.9e-12 45.6 0.0 6e-11 42.4 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EGO51607.1 - 0.00011 22.3 0.0 0.00035 20.7 0.0 1.9 1 0 0 1 1 1 1 PH domain adh_short_C2 PF13561.1 EGO51609.1 - 2.4e-25 89.7 0.0 3.5e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGO51609.1 - 4.6e-20 72.2 0.1 6.2e-20 71.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO51609.1 - 1.1e-09 38.2 0.1 1.6e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO51609.1 - 0.0016 17.9 0.1 0.0031 16.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Carboxyl_trans PF01039.17 EGO51610.1 - 2.6e-140 468.0 0.0 3.2e-140 467.7 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EGO51610.1 - 0.0022 17.2 0.1 2.1 7.4 0.0 2.4 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.19 EGO51611.1 - 2.7e-44 150.8 2.0 5.2e-44 149.9 1.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGO51611.1 - 1.2e-22 80.6 0.5 2.7e-22 79.4 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGO51611.1 - 2.8e-20 71.5 0.3 8.5e-20 70.0 0.1 1.9 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGO51611.1 - 1.9e-15 57.3 0.2 3.2e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EGO51611.1 - 0.00011 21.7 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal NUDIX PF00293.23 EGO51612.1 - 6.6e-11 41.9 0.1 1.3e-06 28.0 0.0 2.1 2 0 0 2 2 2 2 NUDIX domain DLH PF01738.13 EGO51613.1 - 2.4e-14 53.1 0.0 2.8e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGO51613.1 - 0.0026 17.5 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family MMR_HSR1 PF01926.18 EGO51614.1 - 9.3e-12 44.9 0.0 2.4e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGO51614.1 - 0.013 15.3 0.1 0.27 11.0 0.0 2.5 2 0 0 2 2 2 0 Dynamin family FeoB_N PF02421.13 EGO51614.1 - 0.013 14.7 0.1 0.034 13.4 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MobB PF03205.9 EGO51614.1 - 0.031 13.9 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EGO51614.1 - 0.033 14.5 0.1 0.09 13.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 EGO51614.1 - 0.046 12.9 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_17 PF13207.1 EGO51614.1 - 0.077 13.8 0.1 0.25 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGO51614.1 - 0.088 11.9 0.2 0.6 9.2 0.2 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 EGO51614.1 - 0.12 12.2 1.2 0.4 10.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain IIGP PF05049.8 EGO51614.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) HCO3_cotransp PF00955.16 EGO51615.1 - 2.6e-53 181.4 10.3 1.9e-24 86.2 2.4 3.0 2 1 1 3 3 3 3 HCO3- transporter family PHD PF00628.24 EGO51616.1 - 1.6e-10 40.5 2.2 3.8e-10 39.2 1.5 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EGO51616.1 - 0.03 13.6 3.1 0.055 12.8 2.1 1.4 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 EGO51616.1 - 4.8 7.0 6.4 4.8 6.9 0.5 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Glyco_transf_90 PF05686.7 EGO51619.1 - 1.7e-06 27.0 0.3 0.15 10.6 0.0 3.9 4 0 0 4 4 4 3 Glycosyl transferase family 90 zf-DHHC PF01529.15 EGO51620.1 - 7.1e-33 113.4 0.2 7.1e-33 113.4 0.1 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.2 EGO51620.1 - 1.3 8.8 9.5 2.5 7.9 6.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon Transglut_core3 PF13471.1 EGO51620.1 - 2.1 8.1 6.6 0.21 11.3 1.0 1.9 2 0 0 2 2 2 0 Transglutaminase-like superfamily Mpv17_PMP22 PF04117.7 EGO51621.1 - 9.6e-29 98.8 4.0 1.9e-28 97.8 2.7 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Lactamase_B PF00753.22 EGO51622.1 - 2.2e-10 40.5 0.0 3.3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGO51622.1 - 0.096 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain MRL1 PF13003.2 EGO51622.1 - 0.14 11.9 0.1 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L1 Orthopox_A49R PF06489.6 EGO51622.1 - 0.17 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus A49R protein EF-hand_1 PF00036.27 EGO51623.1 - 3.6e-11 41.5 3.2 0.00038 19.5 0.1 4.1 3 0 0 3 3 3 2 EF hand ZZ PF00569.12 EGO51623.1 - 3.5e-09 36.0 8.3 7.2e-09 35.0 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.1 EGO51623.1 - 1.9e-08 34.2 13.3 2.5e-06 27.5 1.9 4.2 3 1 2 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.1 EGO51623.1 - 1.3e-06 27.7 5.0 0.0018 17.9 0.4 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EGO51623.1 - 0.00017 21.1 6.3 0.069 12.7 0.1 3.5 2 1 1 3 3 3 2 EF-hand domain pair C1_3 PF07649.7 EGO51623.1 - 0.09 12.8 9.0 0.18 11.8 6.2 1.5 1 0 0 1 1 1 0 C1-like domain EF-hand_5 PF13202.1 EGO51623.1 - 1.1 8.6 6.2 0.96 8.9 0.4 3.5 3 0 0 3 3 3 0 EF hand Cyclin_N PF00134.18 EGO51625.1 - 9.5e-39 131.8 0.6 1.8e-38 130.9 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGO51625.1 - 4.7e-10 39.4 0.0 1.2e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain UQ_con PF00179.21 EGO51627.1 - 3.4e-47 159.4 0.0 3.9e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO51627.1 - 0.00012 21.8 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EGO51627.1 - 0.0056 16.3 0.1 0.011 15.4 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EGO51627.1 - 0.032 14.1 0.1 0.05 13.4 0.0 1.5 2 0 0 2 2 2 0 RWD domain WD40 PF00400.27 EGO51628.1 - 8.4e-12 44.4 18.6 3.1e-07 30.0 0.3 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 EGO51628.1 - 0.07 12.9 12.0 0.15 11.9 8.3 1.5 1 0 0 1 1 1 0 Ring finger domain Myosin_head PF00063.16 EGO51629.1 - 2.3e-231 769.6 1.6 5.2e-231 768.4 1.1 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EGO51629.1 - 1.4e-39 135.4 0.0 4.1e-39 133.9 0.0 1.9 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 EGO51629.1 - 4.4e-13 48.3 0.2 9.2e-13 47.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGO51629.1 - 1.3e-10 40.6 0.1 3.3e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGO51629.1 - 1.3e-08 34.1 0.0 3.2e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 EGO51629.1 - 0.0077 16.3 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGO51629.1 - 0.017 14.2 0.1 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin IQ PF00612.22 EGO51629.1 - 0.017 14.6 13.1 0.044 13.4 1.7 2.6 1 1 1 2 2 2 0 IQ calmodulin-binding motif Hpr_kinase_C PF07475.7 EGO51629.1 - 0.044 13.1 0.2 4.1 6.6 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF552 PF04472.7 EGO51629.1 - 0.073 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF552) AAA_17 PF13207.1 EGO51629.1 - 0.086 13.6 0.0 0.24 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGO51629.1 - 0.14 11.8 0.1 0.33 10.5 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EGO51629.1 - 0.16 11.9 0.0 0.62 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain NAD_binding_6 PF08030.7 EGO51630.1 - 3.8e-23 82.1 0.0 6.6e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGO51630.1 - 1.1e-22 79.8 0.0 2.4e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGO51630.1 - 7.5e-18 64.8 9.4 7.5e-18 64.8 6.5 2.4 2 1 1 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGO51630.1 - 0.00077 19.5 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGO51630.1 - 0.099 13.2 0.0 2.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain UDPGP PF01704.13 EGO51631.1 - 1.4e-55 188.5 0.0 2e-55 187.9 0.0 1.3 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EGO51631.1 - 0.035 14.1 0.1 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 MobA-like NTP transferase domain Fer4_20 PF14691.1 EGO51631.1 - 0.084 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster BolA PF01722.13 EGO51632.1 - 7.7e-28 96.2 1.7 9.3e-28 96.0 1.2 1.1 1 0 0 1 1 1 1 BolA-like protein AMP-binding PF00501.23 EGO51634.1 - 4.5e-75 252.5 0.0 5.4e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO51634.1 - 5.5e-13 49.6 0.1 1.3e-12 48.4 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain VID27 PF08553.5 EGO51635.1 - 0.0051 15.1 0.1 0.0051 15.1 0.1 2.0 2 0 0 2 2 2 1 VID27 cytoplasmic protein G-patch PF01585.18 EGO51635.1 - 0.092 12.5 5.3 0.84 9.4 2.1 3.3 2 1 0 2 2 2 0 G-patch domain CAF-1_p150 PF11600.3 EGO51635.1 - 0.39 10.0 51.3 0.54 9.5 35.6 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal UPF0560 PF10577.4 EGO51635.1 - 1.1 7.4 10.7 1.2 7.3 7.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CENP-N PF05238.8 EGO51635.1 - 1.9 7.4 14.0 2.2 7.2 9.7 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Thg1C PF14413.1 EGO51636.1 - 5.7e-53 177.7 0.3 7.9e-53 177.2 0.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EGO51636.1 - 1.5e-48 163.8 0.0 2.2e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase WD40 PF00400.27 EGO51637.1 - 3.8e-15 55.0 2.5 3.2e-05 23.6 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EGO51637.1 - 2.9e-06 27.1 0.1 0.034 13.8 0.0 3.4 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EGO51637.1 - 0.022 14.1 0.0 0.099 12.0 0.0 2.2 1 1 1 2 2 2 0 PQQ-like domain DUF4440 PF14534.1 EGO51637.1 - 0.052 13.7 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) RNA_pol_Rpb1_1 PF04997.7 EGO51638.1 - 1.7e-111 372.7 0.0 3.3e-111 371.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EGO51638.1 - 1.5e-101 339.2 0.2 3.6e-101 338.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EGO51638.1 - 5.6e-70 234.5 0.0 1.2e-69 233.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EGO51638.1 - 2.1e-58 197.1 1.1 7.3e-58 195.4 1.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EGO51638.1 - 2e-46 157.5 0.0 5.8e-46 156.0 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EGO51638.1 - 1.3e-44 151.1 3.4 4.8e-44 149.3 2.2 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EGO51638.1 - 6.7e-37 125.5 0.1 1.6e-36 124.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Acetyltransf_7 PF13508.1 EGO51639.1 - 9.9e-10 38.4 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO51639.1 - 4.7e-08 32.9 0.1 8.9e-08 32.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGO51639.1 - 2.4e-05 24.0 0.0 6.4e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGO51639.1 - 0.00026 21.0 0.0 0.00036 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HTH_31 PF13560.1 EGO51639.1 - 0.011 15.9 0.0 0.042 14.0 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Acetyltransf_9 PF13527.1 EGO51639.1 - 0.042 13.7 0.0 0.12 12.2 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain HET PF06985.6 EGO51640.1 - 2.6e-24 85.9 0.2 4.5e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LMBR1 PF04791.11 EGO51642.1 - 1.5e-18 66.6 15.3 2.2e-18 66.1 2.9 2.3 1 1 0 2 2 2 2 LMBR1-like membrane protein Peptidase_M50 PF02163.17 EGO51642.1 - 0.0036 16.2 0.4 0.24 10.3 0.3 2.8 1 1 0 1 1 1 1 Peptidase family M50 Ycf1 PF05758.7 EGO51642.1 - 0.14 9.8 0.1 0.22 9.1 0.0 1.2 1 0 0 1 1 1 0 Ycf1 TCL1_MTCP1 PF01840.12 EGO51644.1 - 0.1 12.0 0.6 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 TCL1/MTCP1 family adh_short_C2 PF13561.1 EGO51646.1 - 1e-29 104.0 0.0 1.5e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGO51646.1 - 3.1e-27 95.5 1.3 4.4e-27 95.0 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO51646.1 - 7e-15 55.1 0.7 1.1e-14 54.4 0.5 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.1 EGO51646.1 - 0.00028 21.0 0.0 0.00052 20.2 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding 3Beta_HSD PF01073.14 EGO51646.1 - 0.068 11.8 0.1 0.097 11.3 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Globin PF00042.17 EGO51647.1 - 1.6e-11 44.4 0.0 2.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 EGO51647.1 - 4.3e-11 43.3 0.0 9.1e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGO51647.1 - 9.7e-10 38.4 0.0 1.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGO51647.1 - 0.00066 19.6 0.9 0.0091 15.9 0.2 2.6 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Protoglobin PF11563.3 EGO51647.1 - 0.0053 16.4 0.0 0.014 15.0 0.0 1.8 1 1 0 1 1 1 1 Protoglobin PAT1 PF09770.4 EGO51649.1 - 2.2 6.4 26.2 2.7 6.1 18.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zn_clus PF00172.13 EGO51651.1 - 2.5e-06 27.2 9.4 2.5e-06 27.2 6.5 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGO51651.1 - 1.3e-05 24.1 0.5 1.3e-05 24.1 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Caudal_act PF04731.7 EGO51652.1 - 0.059 13.6 1.1 0.074 13.3 0.8 1.3 1 0 0 1 1 1 0 Caudal like protein activation region Glyco_hydro_47 PF01532.15 EGO51654.1 - 2.1e-133 445.3 0.0 3e-133 444.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pribosyltran PF00156.22 EGO51655.1 - 4.3e-17 61.9 0.0 5.8e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGO51655.1 - 0.0015 17.8 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase MFS_1_like PF12832.2 EGO51656.1 - 1e-16 60.5 0.1 1e-16 60.5 0.0 2.5 3 0 0 3 3 3 1 MFS_1 like family Cytochrom_B558a PF05038.8 EGO51656.1 - 3.7 7.1 6.9 0.31 10.6 0.2 2.4 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit SET PF00856.23 EGO51657.1 - 1.2e-11 45.2 0.3 6.4e-11 42.8 0.0 2.3 2 1 0 2 2 2 1 SET domain DUF908 PF06012.7 EGO51657.1 - 0.34 10.1 1.9 0.46 9.7 1.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) BAF1_ABF1 PF04684.8 EGO51660.1 - 0.12 11.1 13.3 0.18 10.5 9.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Neur_chan_memb PF02932.11 EGO51660.1 - 0.21 11.4 5.6 0.55 10.0 3.9 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.1 EGO51660.1 - 0.34 10.3 15.3 0.55 9.6 10.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Suf PF05843.9 EGO51660.1 - 0.71 9.5 13.0 0.018 14.7 4.7 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) FimP PF09766.4 EGO51660.1 - 1.8 7.5 18.0 3.1 6.7 12.5 1.3 1 0 0 1 1 1 0 Fms-interacting protein CDC45 PF02724.9 EGO51660.1 - 1.9 6.4 10.0 2.6 5.9 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein CDK5_activator PF03261.10 EGO51660.1 - 4 6.6 15.8 7.6 5.7 10.9 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein NARP1 PF12569.3 EGO51660.1 - 4.4 5.9 12.0 6.3 5.4 8.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Kei1 PF08552.6 EGO51660.1 - 5.9 6.5 7.0 10 5.7 4.8 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 FYDLN_acid PF09538.5 EGO51660.1 - 6.8 7.3 9.8 25 5.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) SRP-alpha_N PF04086.8 EGO51660.1 - 9.4 5.5 18.9 16 4.7 13.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3176 PF11374.3 EGO51662.1 - 1.4e-35 121.4 1.7 3e-35 120.4 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Arginase PF00491.16 EGO51663.1 - 1.2e-65 221.5 0.6 1.6e-65 221.1 0.4 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EGO51663.1 - 0.076 13.2 0.2 0.16 12.1 0.2 1.7 1 1 0 1 1 1 0 UPF0489 domain PIP5K PF01504.13 EGO51664.1 - 4.3e-57 193.1 0.0 8.6e-57 192.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EGO51664.1 - 1.1e-27 96.7 0.0 1.7e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EGO51664.1 - 2.5e-15 56.1 13.2 2.5e-15 56.1 9.1 2.1 2 0 0 2 2 2 1 FYVE zinc finger YbaB_DNA_bd PF02575.11 EGO51664.1 - 0.44 10.4 5.0 0.28 11.1 0.8 2.4 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family CPSF_A PF03178.10 EGO51665.1 - 4.2e-86 288.9 0.0 9e-86 287.8 0.0 1.6 2 0 0 2 2 2 1 CPSF A subunit region CKS PF01111.14 EGO51670.1 - 2.8e-35 119.9 0.9 3.6e-35 119.6 0.7 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.20 EGO51671.1 - 8.9e-38 128.0 0.1 1.1e-17 63.6 0.1 2.4 2 0 0 2 2 2 2 Bromodomain Daxx PF03344.10 EGO51671.1 - 0.13 10.7 9.3 0.19 10.1 6.5 1.2 1 0 0 1 1 1 0 Daxx Family Ebola_NP PF05505.7 EGO51671.1 - 4.1 5.3 8.5 7.3 4.5 5.9 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein YfhD PF14151.1 EGO51672.1 - 0.064 13.3 2.1 0.22 11.6 1.4 1.9 1 0 0 1 1 1 0 YfhD-like protein IF4E PF01652.13 EGO51673.1 - 8.5e-61 204.2 0.1 1e-60 204.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E HSP70 PF00012.15 EGO51674.1 - 8.5e-234 776.9 8.7 9.6e-234 776.7 6.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGO51674.1 - 7.4e-18 64.2 0.3 7e-17 61.0 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EGO51674.1 - 0.0048 16.5 0.0 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EGO51674.1 - 0.052 13.3 6.2 0.66 9.8 0.6 3.8 3 1 0 3 3 3 0 Cell division protein FtsA ERO1 PF04137.10 EGO51675.1 - 4.8e-139 463.3 0.7 6.6e-138 459.5 0.0 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Spore_GerQ PF09671.5 EGO51675.1 - 0.0085 15.7 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 1 Spore coat protein (Spore_GerQ) HVSL PF09749.4 EGO51676.1 - 1.1e-83 279.8 0.0 1.4e-83 279.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 EGO51676.1 - 2.5e-05 24.0 0.0 5.6e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Cytokin_check_N PF10407.4 EGO51676.1 - 0.13 11.9 0.0 1.6 8.3 0.0 2.5 3 0 0 3 3 3 0 Cdc14 phosphatase binding protein N-terminus Proho_convert PF12177.3 EGO51677.1 - 0.11 12.1 1.2 0.14 11.7 0.9 1.2 1 0 0 1 1 1 0 Prohormone convertase enzyme Pal1 PF08316.6 EGO51678.1 - 4.7e-11 43.3 0.1 9.4e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 Pal1 cell morphology protein Pex2_Pex12 PF04757.9 EGO51679.1 - 4.5e-41 140.7 2.9 7.8e-41 139.9 2.0 1.4 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EGO51679.1 - 0.0038 17.0 4.0 0.0075 16.1 2.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Ferric_reduct PF01794.14 EGO51679.1 - 0.03 14.4 2.0 0.055 13.5 1.4 1.3 1 0 0 1 1 1 0 Ferric reductase like transmembrane component zf-RING_UBOX PF13445.1 EGO51679.1 - 0.033 13.9 0.8 0.17 11.5 0.1 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EGO51679.1 - 0.13 12.2 8.9 0.051 13.6 3.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) 3HCDH_N PF02737.13 EGO51680.1 - 8.5e-32 110.2 0.0 2.4e-31 108.7 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IBN_N PF03810.14 EGO51680.1 - 1.1e-14 54.0 0.1 4.2e-14 52.2 0.1 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain 3HCDH PF00725.17 EGO51680.1 - 1.1e-12 48.1 0.0 2.6e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Xpo1 PF08389.7 EGO51680.1 - 4.8e-05 23.3 0.2 0.0014 18.5 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein NAD_binding_2 PF03446.10 EGO51680.1 - 0.0012 18.7 0.0 0.0037 17.1 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase SGL PF08450.7 EGO51680.1 - 0.017 14.4 0.0 0.25 10.7 0.0 2.3 1 1 2 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region UME PF08064.8 EGO51680.1 - 0.02 14.8 1.2 4 7.4 0.1 2.8 1 1 1 2 2 2 0 UME (NUC010) domain 2-Hacid_dh_C PF02826.14 EGO51680.1 - 0.024 13.7 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EGO51680.1 - 0.025 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DNA_ligase_A_N PF04675.9 EGO51680.1 - 0.026 14.3 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 DNA ligase N terminus BRCT PF00533.21 EGO51681.1 - 0.082 13.0 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF2404 PF10296.4 EGO51682.1 - 0.00077 19.5 0.0 0.0028 17.7 0.0 1.8 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) VPS28 PF03997.7 EGO51683.1 - 4e-55 186.3 0.0 4.7e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 EGO51683.1 - 0.0035 17.0 2.8 0.051 13.3 0.2 2.2 2 0 0 2 2 2 2 Gas vesicle protein G Noc2 PF03715.8 EGO51684.1 - 2.8e-123 410.5 0.0 2.8e-123 410.5 0.0 1.7 2 0 0 2 2 2 1 Noc2p family DUF726 PF05277.7 EGO51685.1 - 1.1e-110 369.7 1.8 1.9e-110 369.0 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.15 EGO51685.1 - 7.6e-05 23.0 0.0 0.00016 21.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EGO51685.1 - 0.00034 20.5 0.2 0.0011 18.9 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO51685.1 - 0.0076 16.0 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EGO51685.1 - 0.0084 15.8 0.0 0.024 14.3 0.0 1.7 2 0 0 2 2 2 1 Cutinase EIAV_GP90 PF00971.13 EGO51685.1 - 0.2 10.0 0.0 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 EIAV coat protein, gp90 Gly-zipper_OmpA PF13436.1 EGO51685.1 - 8.9 6.0 11.9 12 5.5 0.1 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain ApoO PF09769.4 EGO51686.1 - 4.4e-59 198.7 0.1 9.5e-59 197.6 0.0 1.6 2 0 0 2 2 2 1 Apolipoprotein O Peptidase_M3 PF01432.15 EGO51688.1 - 2.3e-123 412.6 0.0 4.1e-123 411.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EGO51688.1 - 0.012 15.0 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like WSC PF01822.14 EGO51690.1 - 9.9e-20 70.2 5.4 2e-19 69.3 3.7 1.5 1 0 0 1 1 1 1 WSC domain WLM PF08325.5 EGO51691.1 - 5.8e-58 195.8 1.4 4.3e-56 189.7 0.0 2.4 2 0 0 2 2 2 1 WLM domain zf-RanBP PF00641.13 EGO51691.1 - 0.00045 19.2 2.9 0.00045 19.2 2.0 3.5 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 EGO51691.1 - 0.0038 16.9 11.4 0.11 12.2 0.5 2.3 2 0 0 2 2 2 2 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 EGO51691.1 - 0.0078 15.7 12.8 0.13 11.8 0.1 3.4 2 1 1 3 3 3 2 Sec23/Sec24 zinc finger DUF45 PF01863.12 EGO51691.1 - 0.014 15.2 0.3 0.014 15.2 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function DUF45 SprT-like PF10263.4 EGO51691.1 - 0.083 12.5 2.7 0.96 9.0 0.0 2.9 3 0 0 3 3 3 0 SprT-like family DUF3243 PF11588.3 EGO51691.1 - 0.15 12.0 2.5 0.81 9.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) PHD PF00628.24 EGO51691.1 - 7.1 6.4 15.6 0.42 10.3 1.3 3.0 2 1 1 3 3 3 0 PHD-finger Asp PF00026.18 EGO51692.1 - 1e-61 208.9 1.6 1.4e-61 208.5 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO51692.1 - 1.2e-05 25.3 0.1 3.4e-05 23.8 0.1 1.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO51692.1 - 0.00011 22.6 0.5 0.004 17.6 0.2 2.7 2 1 0 2 2 2 1 Aspartyl protease APC_CDC26 PF10471.4 EGO51693.1 - 2.5e-10 40.9 10.5 2.5e-10 40.9 7.3 6.1 5 2 0 5 5 5 1 Anaphase-promoting complex APC subunit 1 HATPase_c PF02518.21 EGO51694.1 - 2.7e-29 101.1 0.1 5e-29 100.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGO51694.1 - 5e-23 81.2 0.0 9.8e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EGO51694.1 - 5.6e-22 77.5 0.2 1.8e-21 75.9 0.2 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EGO51694.1 - 5.6e-20 71.6 0.0 3.1e-11 43.5 0.0 3.9 4 0 0 4 4 4 3 PAS domain PAS_3 PF08447.6 EGO51694.1 - 1.3e-17 63.7 0.3 5.4e-17 61.6 0.2 2.2 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EGO51694.1 - 8.2e-09 35.4 0.0 4.7e-05 23.3 0.0 4.1 4 1 0 4 4 4 2 PAS fold PAS PF00989.19 EGO51694.1 - 1.3e-06 28.1 0.0 0.22 11.2 0.0 4.2 5 0 0 5 5 5 2 PAS fold PAS_8 PF13188.1 EGO51694.1 - 4.7e-05 23.1 0.0 0.023 14.5 0.0 3.4 3 0 0 3 3 3 1 PAS domain HATPase_c_3 PF13589.1 EGO51694.1 - 0.0012 18.4 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Aldedh PF00171.17 EGO51695.1 - 1.8e-137 458.4 0.4 2.2e-137 458.1 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family IU_nuc_hydro PF01156.14 EGO51696.1 - 1.8e-79 267.1 0.0 2.1e-79 266.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.8 EGO51697.1 - 1.3e-07 31.1 15.1 1.3e-07 31.1 10.5 2.5 1 1 0 1 1 1 1 RED-like protein N-terminal region SHOCT PF09851.4 EGO51697.1 - 0.0098 15.3 9.6 0.0098 15.3 6.7 3.9 4 0 0 4 4 4 1 Short C-terminal domain IMS PF00817.15 EGO51698.1 - 1.5e-42 144.8 0.0 3e-42 143.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGO51698.1 - 1e-18 67.4 0.0 2.3e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EGO51698.1 - 3.7e-17 62.2 5.4 1.8e-08 34.2 0.1 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 EGO51698.1 - 1.3e-05 24.9 0.3 7.3e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 IMS family HHH motif BRCT PF00533.21 EGO51698.1 - 0.00011 22.2 0.0 0.00038 20.5 0.0 2.0 2 0 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.1 EGO51698.1 - 0.0024 17.9 0.1 0.008 16.3 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain MgtE_N PF03448.12 EGO51698.1 - 0.0036 17.5 4.5 7.4 6.9 0.0 4.6 6 0 0 6 6 6 1 MgtE intracellular N domain PTCB-BRCT PF12738.2 EGO51698.1 - 0.0079 16.0 0.0 0.025 14.4 0.0 2.0 1 0 0 1 1 1 1 twin BRCT domain DUF2365 PF10157.4 EGO51698.1 - 0.065 13.1 0.4 2.6 7.9 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) DUF1805 PF08827.6 EGO51698.1 - 0.076 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Cdd1 PF11731.3 EGO51698.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus FliG_M PF14841.1 EGO51698.1 - 0.31 11.0 6.4 7 6.7 0.1 4.5 6 0 0 6 6 6 0 FliG middle domain Peptidase_M1 PF01433.15 EGO51699.1 - 2.6e-06 26.7 0.0 0.22 10.5 0.0 3.2 3 0 0 3 3 3 3 Peptidase family M1 SAS4 PF15460.1 EGO51700.1 - 1.2e-36 124.6 0.7 2.9e-36 123.3 0.5 1.7 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 ABC_tran PF00005.22 EGO51701.1 - 3.7e-35 121.1 0.0 1.6e-18 67.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGO51701.1 - 3.8e-32 111.8 30.3 6.4e-19 68.4 10.4 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EGO51701.1 - 2.6e-10 39.9 2.0 0.049 12.8 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EGO51701.1 - 1e-06 27.8 0.4 0.03 13.2 0.0 3.3 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_21 PF13304.1 EGO51701.1 - 1.7e-06 28.2 0.0 0.039 13.9 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 EGO51701.1 - 7.2e-06 26.4 0.0 0.0073 16.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGO51701.1 - 1.2e-05 24.7 0.3 0.0056 16.1 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EGO51701.1 - 1.3e-05 24.4 0.1 0.012 14.7 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.1 EGO51701.1 - 1.4e-05 25.1 0.2 0.17 11.8 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EGO51701.1 - 1.9e-05 24.8 0.1 0.45 10.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EGO51701.1 - 4.4e-05 23.3 0.0 0.036 13.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGO51701.1 - 0.00014 22.0 0.2 0.58 10.3 0.1 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EGO51701.1 - 0.0002 21.2 0.3 0.063 13.1 0.0 3.6 3 0 0 3 3 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EGO51701.1 - 0.00022 20.4 0.2 0.12 11.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 EGO51701.1 - 0.00035 20.1 0.6 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EGO51701.1 - 0.00084 18.7 0.2 0.076 12.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EGO51701.1 - 0.00091 18.9 0.1 1.4 8.5 0.0 2.4 2 0 0 2 2 2 2 Archaeal ATPase MMR_HSR1 PF01926.18 EGO51701.1 - 0.0022 17.9 0.0 1.2 9.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGO51701.1 - 0.0034 17.2 0.3 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 EGO51701.1 - 0.0036 17.7 0.0 0.26 11.8 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 EGO51701.1 - 0.0037 16.7 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain MobB PF03205.9 EGO51701.1 - 0.005 16.5 1.4 2.7 7.6 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EGO51701.1 - 0.0092 16.7 0.0 8.8 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EGO51701.1 - 0.017 14.7 0.4 6 6.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.13 EGO51701.1 - 0.033 13.6 0.3 0.093 12.1 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 EGO51701.1 - 0.036 13.5 1.8 3.9 6.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_PrkA PF08298.6 EGO51701.1 - 0.056 12.1 0.0 6.4 5.3 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain IstB_IS21 PF01695.12 EGO51701.1 - 0.059 12.7 0.2 14 5.0 0.1 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.17 EGO51701.1 - 0.075 11.8 0.0 4.7 5.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain FSA_C PF10479.4 EGO51701.1 - 0.089 10.8 0.0 0.15 10.0 0.0 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus AAA_5 PF07728.9 EGO51701.1 - 0.17 11.5 1.0 14 5.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EGO51701.1 - 0.22 11.0 0.1 6.1 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGO51701.1 - 0.26 11.5 1.5 30 4.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.1 EGO51701.1 - 0.57 9.1 0.0 18 4.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Reo_sigmaC PF04582.7 EGO51702.1 - 0.0086 15.2 40.4 0.038 13.1 0.4 5.5 3 1 4 7 7 7 5 Reovirus sigma C capsid protein VPS9 PF02204.13 EGO51703.1 - 2.4e-19 69.2 0.0 4.9e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 EGO51703.1 - 1e-17 63.7 2.1 8e-12 44.9 0.0 5.3 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO51703.1 - 2.7e-13 50.0 0.1 5.1e-05 23.5 0.0 3.8 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO51703.1 - 6.7e-09 36.0 0.2 0.00079 19.8 0.0 4.7 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO51703.1 - 7.9e-09 34.9 0.3 0.1 12.8 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.25 EGO51703.1 - 3.3e-06 26.6 3.2 0.0055 16.4 0.0 4.7 6 0 0 6 6 6 2 Ankyrin repeat PX PF00787.19 EGO51703.1 - 0.00064 19.4 0.2 0.0041 16.9 0.0 2.3 2 0 0 2 2 2 1 PX domain PTP_N PF12453.3 EGO51704.1 - 0.83 9.3 6.0 0.95 9.1 2.6 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal YchF-GTPase_C PF06071.8 EGO51705.1 - 1.8e-34 117.3 0.1 5.1e-34 115.9 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EGO51705.1 - 1.5e-12 47.4 0.0 3.5e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO51705.1 - 0.00046 19.4 0.0 0.00084 18.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EGO51705.1 - 0.0013 18.5 0.0 0.0041 16.9 0.0 1.8 1 0 0 1 1 1 1 TGS domain AAA_18 PF13238.1 EGO51705.1 - 0.008 16.4 0.2 3.5 7.9 0.4 3.0 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EGO51705.1 - 0.026 14.2 0.5 4 7.1 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B BetaGal_dom3 PF13363.1 EGO51705.1 - 0.04 13.3 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 AAA_14 PF13173.1 EGO51705.1 - 0.049 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EGO51705.1 - 0.094 12.5 0.2 2.7 7.7 0.0 2.7 1 1 2 3 3 3 0 Dynamin family ABC_tran PF00005.22 EGO51705.1 - 0.29 11.4 1.3 4.7 7.4 0.1 2.3 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 EGO51705.1 - 6.1 7.1 8.8 2.7e+02 1.7 6.1 2.3 1 1 0 1 1 1 0 AAA domain Peptidase_C97 PF05903.9 EGO51706.1 - 2.3e-33 115.0 0.0 3e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EGO51706.1 - 0.00024 21.0 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase 3Beta_HSD PF01073.14 EGO51707.1 - 3.3e-23 81.7 0.0 2e-22 79.2 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGO51707.1 - 8.9e-18 64.5 0.0 1.3e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGO51707.1 - 2.5e-12 46.2 0.0 6.1e-12 45.0 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGO51707.1 - 2.4e-09 37.4 0.5 2.2e-08 34.2 0.4 2.3 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EGO51707.1 - 2.8e-08 33.8 1.4 3.6e-08 33.4 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGO51707.1 - 1.7e-07 31.0 0.4 3.8e-07 29.9 0.2 1.5 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EGO51707.1 - 0.0036 16.2 0.0 0.023 13.6 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain TrkA_N PF02254.13 EGO51707.1 - 0.029 14.3 0.2 0.19 11.7 0.0 2.0 1 1 1 2 2 2 0 TrkA-N domain Polysacc_synt_2 PF02719.10 EGO51707.1 - 0.033 13.0 0.0 0.061 12.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AF1Q PF15017.1 EGO51707.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Nucleoplasmin PF03066.10 EGO51709.1 - 4.2 6.8 7.9 7.3 6.1 5.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin IBR PF01485.16 EGO51710.1 - 2.1e-10 40.3 26.8 4e-07 29.8 5.1 3.8 3 1 0 3 3 3 2 IBR domain zf-C3HC4_3 PF13920.1 EGO51713.1 - 7.1e-07 28.8 2.4 7.1e-07 28.8 1.7 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO51713.1 - 9.7e-07 28.4 0.3 9.7e-07 28.4 0.2 2.4 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGO51713.1 - 1.6e-05 24.5 2.3 1.6e-05 24.5 1.6 2.3 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGO51713.1 - 5.9e-05 22.6 1.4 5.9e-05 22.6 0.9 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGO51713.1 - 0.0041 16.7 1.1 0.088 12.5 0.0 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EGO51713.1 - 0.0052 16.7 5.6 0.0052 16.7 3.9 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2457 PF10446.4 EGO51713.1 - 0.058 12.1 19.8 0.088 11.5 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EGO51713.1 - 0.32 8.9 6.7 0.43 8.5 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EGO51713.1 - 0.54 8.6 11.4 1.1 7.6 7.9 1.4 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EGO51713.1 - 0.9 7.3 12.6 1.3 6.8 8.7 1.2 1 0 0 1 1 1 0 Nop14-like family zf-C3HC4_4 PF15227.1 EGO51713.1 - 1.2 9.1 15.3 0.041 13.7 3.6 3.2 3 1 0 3 3 2 0 zinc finger of C3HC4-type, RING VID27 PF08553.5 EGO51713.1 - 2 6.5 7.6 3 5.9 5.3 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein BUD22 PF09073.5 EGO51713.1 - 2.8 6.9 10.4 4.3 6.2 7.2 1.3 1 0 0 1 1 1 0 BUD22 Prok-RING_1 PF14446.1 EGO51713.1 - 4.4 7.1 14.8 0.044 13.5 4.6 2.0 2 0 0 2 2 1 0 Prokaryotic RING finger family 1 TRAP_alpha PF03896.11 EGO51713.1 - 5.5 5.9 9.4 9.5 5.1 6.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.6 EGO51713.1 - 5.6 4.7 11.1 8.2 4.1 7.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.7 EGO51713.1 - 7.3 5.7 16.0 12 5.0 11.1 1.3 1 0 0 1 1 1 0 SDA1 DUF2722 PF10846.3 EGO51713.1 - 8.3 5.3 6.6 12 4.7 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SEN1_N PF12726.2 EGO51714.1 - 9.6e-202 671.9 0.5 1.2e-201 671.5 0.4 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EGO51714.1 - 7.3e-71 238.4 0.8 7.3e-71 238.4 0.6 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EGO51714.1 - 2e-63 213.3 0.0 3.8e-63 212.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO51714.1 - 1.4e-11 44.0 0.4 4.1e-11 42.4 0.3 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGO51714.1 - 1.8e-08 34.1 0.2 1.3e-05 24.8 0.1 2.7 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 EGO51714.1 - 2.5e-07 30.2 2.5 8.2e-06 25.3 0.0 2.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 EGO51714.1 - 3.1e-05 23.6 1.1 0.012 15.1 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 EGO51714.1 - 0.0043 17.3 0.6 0.0043 17.3 0.4 2.8 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 EGO51714.1 - 0.016 14.6 0.4 0.083 12.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGO51714.1 - 0.021 14.9 0.7 2.7 8.1 0.0 3.6 3 0 0 3 3 3 0 AAA domain DUF1062 PF06353.7 EGO51714.1 - 0.3 11.2 4.7 5.4 7.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1062) HhH-GPD PF00730.20 EGO51715.1 - 2.1e-12 47.2 0.0 4.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DNA_methylase PF00145.12 EGO51717.1 - 1e-39 136.6 0.0 2.8e-31 108.8 0.0 2.5 2 1 1 3 3 3 2 C-5 cytosine-specific DNA methylase EAF PF09816.4 EGO51718.1 - 1.3e-20 73.4 0.0 3.2e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor CBM_6 PF03422.10 EGO51718.1 - 0.071 13.2 0.1 0.22 11.6 0.1 1.8 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) Glyco_hydro_76 PF03663.9 EGO51719.1 - 3e-154 513.9 20.5 4e-154 513.4 14.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 p450 PF00067.17 EGO51720.1 - 4.4e-65 219.9 0.0 5.8e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Flavi_NS5 PF00972.15 EGO51720.1 - 0.011 13.7 0.0 0.014 13.3 0.0 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase ComX PF05952.7 EGO51720.1 - 0.11 12.0 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Bacillus competence pheromone ComX DUF2130 PF09903.4 EGO51721.1 - 0.021 13.5 0.0 0.028 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) LigB PF02900.13 EGO51723.1 - 5.2e-58 196.1 0.2 5.9e-58 196.0 0.1 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Abhydrolase_2 PF02230.11 EGO51724.1 - 1.8e-62 210.6 0.0 2.2e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGO51724.1 - 3.7e-12 46.2 0.0 1.1e-11 44.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO51724.1 - 6.1e-10 39.3 0.1 5.7e-05 23.1 0.1 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 EGO51724.1 - 6.4e-07 29.0 0.0 2.2e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EGO51724.1 - 9.6e-07 28.2 0.1 0.00012 21.3 0.0 2.7 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EGO51724.1 - 0.0014 18.2 0.1 1.5 8.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 EGO51724.1 - 0.0048 16.2 0.0 0.0094 15.2 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EGO51724.1 - 0.011 15.3 0.1 2.2 7.7 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Phage_H_T_join PF05521.6 EGO51725.1 - 0.061 13.6 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Phage head-tail joining protein FliD_N PF02465.13 EGO51725.1 - 0.11 12.9 6.7 0.34 11.2 0.1 3.4 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus TRI12 PF06609.8 EGO51728.1 - 9.4e-32 109.9 26.5 1.2e-31 109.5 18.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EGO51728.1 - 6.7e-22 77.6 43.7 1.2e-21 76.8 30.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO51728.1 - 1.2e-09 37.2 34.1 1e-08 34.2 8.5 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter Hce2 PF14856.1 EGO51730.1 - 1.1e-21 76.5 0.0 1.4e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Ferric_reduct PF01794.14 EGO51731.1 - 3.3e-19 69.2 2.4 9.2e-19 67.7 1.7 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EGO51731.1 - 7.8e-15 54.6 0.1 2.9e-14 52.8 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EGO51731.1 - 1e-14 54.7 0.0 7.7e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EGO51731.1 - 0.0033 17.9 0.1 0.18 12.4 0.0 2.8 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain DAO PF01266.19 EGO51732.1 - 5.6e-42 143.9 3.1 8.1e-42 143.3 2.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGO51732.1 - 0.0006 20.1 0.0 0.69 10.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO51732.1 - 0.0015 17.6 2.6 0.0016 17.5 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EGO51732.1 - 0.0016 18.3 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGO51732.1 - 0.011 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EGO51732.1 - 0.062 13.0 0.2 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EGO51732.1 - 0.11 11.1 0.8 0.14 10.7 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase adh_short PF00106.20 EGO51733.1 - 1.2e-24 87.1 1.5 2.9e-24 85.8 1.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO51733.1 - 6.6e-14 52.2 0.3 1e-13 51.6 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO51733.1 - 2e-06 27.5 1.5 9e-06 25.4 1.0 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO51733.1 - 1.6e-05 24.9 0.4 2.7e-05 24.2 0.3 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO51733.1 - 8.4e-05 22.1 0.2 0.00051 19.5 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGO51733.1 - 0.006 16.3 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EGO51733.1 - 0.07 12.3 0.1 0.095 11.9 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family CBFD_NFYB_HMF PF00808.18 EGO51735.1 - 1.3e-16 60.4 0.1 2.5e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGO51735.1 - 0.00017 21.6 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EGO51735.1 - 0.016 14.9 0.1 0.039 13.6 0.0 1.7 2 0 0 2 2 2 0 Bromodomain associated zf-DHHC PF01529.15 EGO51737.1 - 5.5e-39 133.3 2.1 1.2e-38 132.2 1.5 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase Yip1 PF04893.12 EGO51737.1 - 0.076 12.5 0.1 0.076 12.5 0.1 2.0 2 0 0 2 2 2 0 Yip1 domain OppC_N PF12911.2 EGO51737.1 - 6.6 6.1 8.1 11 5.4 1.7 3.1 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C TYW3 PF02676.9 EGO51738.1 - 1.2e-59 200.9 0.0 2.9e-59 199.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase TYW3 MIP-T3 PF10243.4 EGO51738.1 - 0.45 8.9 15.6 0.69 8.3 10.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SR-25 PF10500.4 EGO51738.1 - 8.8 5.7 23.3 1.8 7.9 6.0 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1690 PF07956.6 EGO51739.1 - 6.2e-47 159.1 8.2 7.2e-47 158.9 5.7 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Allexi_40kDa PF05549.6 EGO51739.1 - 0.01 15.1 3.0 0.012 14.9 2.1 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Rep_4 PF05797.6 EGO51739.1 - 0.013 14.2 0.2 0.015 14.0 0.1 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) DUF4071 PF13281.1 EGO51739.1 - 0.049 12.4 3.0 0.061 12.1 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) DUF3779 PF12621.3 EGO51739.1 - 0.13 12.1 1.8 0.44 10.4 0.0 2.4 1 1 2 3 3 3 0 Phosphate metabolism protein DUF342 PF03961.8 EGO51739.1 - 0.13 10.6 3.4 0.15 10.3 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF964 PF06133.6 EGO51739.1 - 0.16 12.0 12.0 0.28 11.2 7.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF964) DUF3708 PF12501.3 EGO51739.1 - 0.2 11.4 3.0 0.31 10.8 2.1 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter DHC PF09626.5 EGO51739.1 - 0.22 12.1 1.5 0.32 11.6 1.1 1.4 1 0 0 1 1 1 0 Dihaem cytochrome c Tox-REase-2 PF15646.1 EGO51739.1 - 0.38 10.6 3.3 0.82 9.5 1.5 2.0 1 1 2 3 3 3 0 Restriction endonuclease fold toxin 2 ALMT PF11744.3 EGO51739.1 - 0.4 9.2 2.7 0.43 9.1 1.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter LPP20 PF02169.11 EGO51739.1 - 0.4 10.7 7.8 0.4 10.8 3.1 2.1 1 1 1 2 2 2 0 LPP20 lipoprotein PAP_central PF04928.12 EGO51739.1 - 0.56 8.9 4.5 0.71 8.6 3.1 1.3 1 1 0 1 1 1 0 Poly(A) polymerase central domain CRA_rpt PF07046.6 EGO51739.1 - 0.97 9.4 5.7 0.28 11.1 1.2 2.2 2 0 0 2 2 2 0 Cytoplasmic repetitive antigen (CRA) like repeat FUSC PF04632.7 EGO51739.1 - 1 7.6 6.6 1.2 7.4 4.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Endonuc_Holl PF10107.4 EGO51739.1 - 1.1 8.9 7.4 1.6 8.3 5.1 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase OmpH PF03938.9 EGO51739.1 - 1.7 8.6 13.2 2.4 8.1 9.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Kinesin-relat_1 PF12711.2 EGO51739.1 - 1.9 8.9 14.4 2 8.8 5.1 2.8 1 1 1 2 2 2 0 Kinesin motor Fungal_trans PF04082.13 EGO51740.1 - 3.4e-12 45.7 0.2 8.3e-12 44.5 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO51740.1 - 0.00098 18.9 7.0 0.0018 18.1 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT PF02985.17 EGO51741.1 - 5.2e-15 54.1 12.0 0.0014 18.5 0.0 10.9 13 0 0 13 13 13 3 HEAT repeat HEAT_2 PF13646.1 EGO51741.1 - 4e-13 49.4 17.2 9.8e-05 22.5 0.0 8.0 3 2 6 9 9 9 4 HEAT repeats HEAT_EZ PF13513.1 EGO51741.1 - 1.5e-12 47.5 9.6 5.7e-07 29.8 0.0 8.8 9 1 2 11 11 11 1 HEAT-like repeat IBN_N PF03810.14 EGO51741.1 - 5.6e-08 32.5 3.5 5.6e-08 32.5 2.4 3.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EGO51741.1 - 7.5e-05 22.1 6.8 0.82 8.9 0.1 5.5 2 2 4 6 6 6 2 CLASP N terminal Arm PF00514.18 EGO51741.1 - 0.00026 20.6 0.7 7 6.6 0.0 5.2 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cse1 PF08506.5 EGO51741.1 - 0.028 13.0 0.0 1.2 7.6 0.0 3.1 3 1 0 3 3 3 0 Cse1 HMGL-like PF00682.14 EGO51742.1 - 3.4e-65 220.0 0.0 6.3e-65 219.1 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EGO51742.1 - 7.9e-24 83.9 0.0 2.7e-23 82.2 0.0 2.0 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain Ferric_reduct PF01794.14 EGO51743.1 - 1.8e-21 76.5 5.9 4.4e-21 75.2 4.1 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EGO51743.1 - 3.3e-18 66.0 0.0 8.6e-16 58.2 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGO51743.1 - 1.3e-09 37.8 0.0 1.2e-07 31.5 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain Complex1_LYR_1 PF13232.1 EGO51745.1 - 8.1e-25 86.8 1.2 1.1e-24 86.4 0.8 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGO51745.1 - 1.8e-23 82.0 1.4 2.4e-23 81.6 1.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EGO51745.1 - 0.00012 22.5 1.7 0.00014 22.2 1.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Toxin_43 PF15604.1 EGO51745.1 - 0.084 12.9 2.8 0.1 12.6 1.9 1.1 1 0 0 1 1 1 0 Putative toxin 43 VitD-bind_III PF09164.5 EGO51745.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 Vitamin D binding protein, domain III PAPS_reduct PF01507.14 EGO51748.1 - 9.5e-38 129.7 0.0 1.2e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.2 EGO51749.1 - 1.9e-16 60.8 0.0 2.8e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO51749.1 - 1.6e-08 35.2 1.0 9.5e-07 29.4 0.7 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGO51749.1 - 2.6e-08 33.7 0.3 2.4e-07 30.5 0.0 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGO51749.1 - 2.7e-05 24.4 0.0 0.00011 22.5 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 EGO51749.1 - 0.00081 18.4 0.1 0.0012 17.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) TIP39 PF14980.1 EGO51749.1 - 0.073 12.7 0.2 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 TIP39 peptide Acid_PPase PF12689.2 EGO51749.1 - 0.18 11.3 0.1 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase GTP_EFTU PF00009.22 EGO51750.1 - 5.4e-57 192.2 0.0 8.1e-57 191.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGO51750.1 - 3.6e-36 123.3 0.0 1.2e-35 121.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGO51750.1 - 1.4e-17 63.5 1.1 1.4e-17 63.5 0.8 2.1 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EGO51750.1 - 0.00026 20.5 0.3 0.00064 19.3 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EGO51750.1 - 0.00052 19.9 0.3 0.0015 18.4 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase SLS PF14611.1 EGO51752.1 - 1.1e-49 168.6 0.0 2.3e-49 167.6 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator MAGE PF01454.14 EGO51753.1 - 1.1e-46 158.6 0.0 1.3e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 MAGE family SF3b10 PF07189.6 EGO51754.1 - 7.1e-43 144.3 0.0 7.9e-43 144.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF2264 PF10022.4 EGO51754.1 - 0.11 11.0 0.0 0.13 10.9 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Septin PF00735.13 EGO51756.1 - 5.9e-36 123.9 0.0 2e-13 49.9 0.0 3.1 3 0 0 3 3 3 3 Septin AAA_23 PF13476.1 EGO51756.1 - 0.0049 17.2 0.0 0.011 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EGO51756.1 - 0.0064 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 EGO51756.1 - 0.0092 15.8 0.1 0.071 12.9 0.0 2.3 3 0 0 3 3 3 1 Dynamin family AAA_17 PF13207.1 EGO51756.1 - 0.012 16.4 0.6 0.29 11.9 0.0 2.7 2 2 0 2 2 2 0 AAA domain Miro PF08477.8 EGO51756.1 - 0.049 14.1 0.0 0.14 12.6 0.0 1.9 1 1 0 1 1 1 0 Miro-like protein Nop14 PF04147.7 EGO51756.1 - 0.053 11.4 4.5 0.023 12.6 1.6 1.4 2 0 0 2 2 2 0 Nop14-like family G-alpha PF00503.15 EGO51756.1 - 0.061 12.0 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit MobB PF03205.9 EGO51756.1 - 0.077 12.6 0.1 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_21 PF13304.1 EGO51756.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGO51756.1 - 0.12 12.6 0.0 2.2 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC1 PF03109.11 EGO51757.1 - 2.5e-21 75.8 0.0 4.9e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EGO51757.1 - 0.011 15.4 0.0 0.03 14.0 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family SUR7 PF06687.7 EGO51759.1 - 8.2e-28 97.4 16.2 1e-27 97.1 11.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family 7TM_GPCR_Srd PF10317.4 EGO51759.1 - 0.0055 15.7 8.5 0.0078 15.2 5.9 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd NfeD PF01957.13 EGO51759.1 - 0.032 14.3 0.9 0.076 13.1 0.5 1.7 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding Pox_P21 PF05313.7 EGO51759.1 - 0.88 8.7 5.1 1.5 8.0 3.5 1.3 1 0 0 1 1 1 0 Poxvirus P21 membrane protein CobD_Cbib PF03186.8 EGO51759.1 - 5.1 6.0 5.2 10 5.1 3.6 1.4 1 1 0 1 1 1 0 CobD/Cbib protein bZIP_1 PF00170.16 EGO51761.1 - 5.7e-09 35.7 16.6 1.2e-08 34.7 11.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGO51761.1 - 0.0059 16.4 18.1 0.0059 16.4 12.5 2.6 2 1 1 3 3 2 1 Basic region leucine zipper HAP1_N PF04849.8 EGO51761.1 - 0.025 13.5 9.1 0.04 12.8 6.3 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region FlaC_arch PF05377.6 EGO51761.1 - 0.031 14.1 4.8 0.064 13.1 3.3 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_Maf PF03131.12 EGO51761.1 - 0.032 14.5 15.4 0.069 13.4 10.7 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2205 PF10224.4 EGO51761.1 - 0.091 12.3 5.0 0.26 10.8 3.5 1.7 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) SIM_C PF06621.7 EGO51761.1 - 0.096 12.2 7.3 0.093 12.2 4.3 1.5 1 1 0 1 1 1 0 Single-minded protein C-terminus BLOC1_2 PF10046.4 EGO51761.1 - 0.12 12.5 5.6 0.2 11.8 1.6 2.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LMSTEN PF07988.7 EGO51761.1 - 0.21 10.9 3.6 3.5 6.9 0.2 2.9 3 0 0 3 3 3 0 LMSTEN motif V_ATPase_I PF01496.14 EGO51761.1 - 0.24 9.1 1.0 0.27 9.0 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF812 PF05667.6 EGO51761.1 - 0.41 9.1 10.9 0.56 8.6 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF972 PF06156.8 EGO51761.1 - 0.59 10.5 8.1 0.21 11.9 3.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TSC22 PF01166.13 EGO51761.1 - 0.86 9.6 6.0 13 5.8 2.8 2.7 1 1 1 2 2 2 0 TSC-22/dip/bun family GAS PF13851.1 EGO51761.1 - 1.1 8.4 14.2 1 8.5 9.2 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Telomere_Sde2 PF13019.1 EGO51761.1 - 1.5 8.4 8.8 3 7.5 6.1 1.5 1 0 0 1 1 1 0 Telomere stability and silencing ADIP PF11559.3 EGO51761.1 - 1.8 8.4 17.5 1.6 8.6 11.3 1.6 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding Tho2 PF11262.3 EGO51761.1 - 3.3 6.6 7.2 5.1 6.0 5.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Atg14 PF10186.4 EGO51761.1 - 3.8 6.3 10.5 5.9 5.7 7.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3584 PF12128.3 EGO51761.1 - 6.6 3.9 17.0 8.9 3.4 11.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.7 EGO51761.1 - 7.3 5.5 10.5 11 4.9 7.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CDP-OH_P_transf PF01066.16 EGO51762.1 - 1.3e-16 60.7 1.6 1.3e-16 60.7 1.1 3.2 4 0 0 4 4 4 1 CDP-alcohol phosphatidyltransferase Adaptin_N PF01602.15 EGO51763.1 - 3.9e-111 371.9 0.4 5e-111 371.6 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EGO51763.1 - 4.4e-58 195.3 1.9 9e-58 194.3 1.3 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EGO51763.1 - 4.4e-15 55.7 2.1 3.4e-05 24.0 0.0 6.2 2 1 3 5 5 5 3 HEAT repeats HEAT_PBS PF03130.11 EGO51763.1 - 0.00056 20.1 0.0 1.2 9.7 0.0 4.4 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat CLASP_N PF12348.3 EGO51763.1 - 0.043 13.1 6.0 0.068 12.5 0.1 3.0 3 1 0 3 3 3 0 CLASP N terminal HEAT PF02985.17 EGO51763.1 - 0.075 13.1 7.6 1.5 9.1 0.1 5.0 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 EGO51763.1 - 2.6 8.6 7.0 0.69 10.4 0.4 3.2 3 0 0 3 3 3 0 HEAT-like repeat Myb_DNA-bind_6 PF13921.1 EGO51764.1 - 0.036 14.1 0.2 0.12 12.4 0.1 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain Herpes_LMP2 PF07415.6 EGO51764.1 - 1 7.8 2.1 1.9 6.9 1.5 1.4 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein UPF0016 PF01169.14 EGO51765.1 - 3.2e-44 148.9 24.2 3.8e-22 78.2 5.9 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 EI24 PF07264.6 EGO51766.1 - 5.1e-08 32.6 7.3 1.3e-07 31.3 5.0 1.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2418 PF10332.4 EGO51766.1 - 0.28 11.5 4.6 13 6.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2418) ATP-sulfurylase PF01747.12 EGO51769.1 - 4.1e-88 294.2 0.0 5.6e-88 293.8 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EGO51769.1 - 6.6e-57 191.5 0.0 1e-56 190.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EGO51769.1 - 1.9e-52 176.9 0.0 2.8e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.5 EGO51769.1 - 0.0005 19.3 0.0 0.00076 18.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EGO51769.1 - 0.0019 18.0 0.1 0.0058 16.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGO51769.1 - 0.055 14.2 0.1 0.7 10.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGO51769.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain MBA1 PF07961.6 EGO51771.1 - 1.2e-08 34.1 0.1 1.6e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 EGO51771.1 - 0.0015 18.5 0.1 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain EOS1 PF12326.3 EGO51772.1 - 1.2e-07 31.4 7.0 2.4e-05 24.0 0.2 2.7 2 1 1 3 3 3 2 N-glycosylation protein SUI1 PF01253.17 EGO51773.1 - 2.3e-29 101.0 5.2 3e-29 100.6 3.6 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 EGO51773.1 - 0.039 14.0 0.1 0.059 13.4 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) DUF2575 PF10837.3 EGO51773.1 - 0.08 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) AdoMet_MTase PF07757.8 EGO51774.1 - 7.1e-40 135.6 0.0 1.1e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 EGO51774.1 - 0.0098 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGO51774.1 - 0.013 15.1 0.0 0.11 12.2 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EGO51774.1 - 0.065 13.8 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Dioxygenase_C PF00775.16 EGO51775.1 - 1.1e-52 177.9 0.0 1.9e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EGO51775.1 - 9.1e-18 64.0 0.0 2.3e-17 62.7 0.0 1.7 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EGO51775.1 - 0.0093 16.0 0.0 0.029 14.4 0.0 1.9 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain TRP PF06011.7 EGO51776.1 - 2.2e-84 283.5 12.2 3.3e-84 282.9 8.5 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGO51776.1 - 6.6e-15 55.3 0.0 1.3e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 ML-like domain SSF PF00474.12 EGO51777.1 - 6.2e-07 28.3 27.9 3.1e-06 26.0 19.4 2.0 1 1 0 1 1 1 1 Sodium:solute symporter family RRM_1 PF00076.17 EGO51779.1 - 4e-19 67.9 0.0 3.9e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO51779.1 - 1.7e-10 40.7 0.0 6.5e-06 26.0 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO51779.1 - 2.5e-05 24.0 0.0 0.003 17.3 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CIA30 PF08547.7 EGO51780.1 - 1.1e-43 148.8 0.0 1.8e-43 148.0 0.0 1.4 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) DUF2407_C PF13373.1 EGO51781.1 - 0.26 11.1 0.0 0.26 11.1 0.0 2.5 2 1 0 2 2 2 0 DUF2407 C-terminal domain MIP-T3 PF10243.4 EGO51781.1 - 0.47 8.8 39.9 0.61 8.4 27.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 JmjC PF02373.17 EGO51782.1 - 1.7e-17 63.6 0.0 1.7e-17 63.6 0.0 2.9 3 1 0 3 3 3 1 JmjC domain, hydroxylase SET PF00856.23 EGO51782.1 - 1e-09 38.9 0.4 3e-08 34.1 0.0 2.6 2 0 0 2 2 2 1 SET domain RRM_6 PF14259.1 EGO51783.1 - 0.0018 18.1 0.0 2.5 8.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO51783.1 - 0.057 13.0 0.0 8.9 6.0 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SlyX PF04102.7 EGO51784.1 - 0.29 11.5 13.1 0.26 11.6 1.0 3.6 2 1 1 3 3 3 0 SlyX ORF6C PF10552.4 EGO51784.1 - 0.41 10.3 3.8 9.9 5.9 0.0 2.7 1 1 1 2 2 2 0 ORF6C domain FlaC_arch PF05377.6 EGO51784.1 - 0.76 9.7 5.5 1.1 9.2 0.4 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 EGO51784.1 - 0.93 8.0 15.5 2.7 6.5 10.2 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.3 EGO51784.1 - 1 9.1 22.4 0.32 10.7 6.2 3.6 4 1 1 5 5 5 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 EGO51784.1 - 1.1 8.1 17.9 2.4 7.0 1.3 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 EGO51784.1 - 2.5 8.4 14.1 1.9 8.8 3.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 EGO51784.1 - 2.8 6.3 8.7 1.7 7.0 4.7 1.6 1 1 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.17 EGO51784.1 - 4.8 7.2 20.1 8.8 6.4 6.4 3.0 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Cep57_MT_bd PF06657.8 EGO51784.1 - 5.1 7.1 18.0 0.35 10.8 3.7 3.9 3 2 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Syntaxin PF00804.20 EGO51784.1 - 5.8 7.1 10.8 10 6.3 3.8 3.3 1 1 3 4 4 4 0 Syntaxin DUF848 PF05852.6 EGO51784.1 - 6.1 6.6 13.6 2.4 7.9 2.8 2.4 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) V-SNARE PF05008.10 EGO51784.1 - 7.6 6.7 14.9 3.1 8.0 6.0 3.4 2 2 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus V_ATPase_I PF01496.14 EGO51784.1 - 8.5 4.0 6.6 13 3.4 4.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 EGO51784.1 - 9.3 6.1 19.6 13 5.6 4.6 3.4 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF718 PF05336.8 EGO51785.1 - 1.7e-35 121.0 0.9 2.2e-35 120.6 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Thioredoxin PF00085.15 EGO51786.1 - 2e-05 24.1 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EGO51786.1 - 0.0025 17.3 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Redoxin DUF953 PF06110.6 EGO51786.1 - 0.042 13.2 0.1 0.47 9.9 0.1 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.1 EGO51786.1 - 0.093 12.9 0.0 2.1 8.5 0.0 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain RebB PF11747.3 EGO51786.1 - 0.099 12.5 0.6 0.099 12.5 0.4 1.5 2 0 0 2 2 2 0 Killing trait MFS_1 PF07690.11 EGO51787.1 - 1e-43 149.3 20.9 4.4e-32 111.1 1.3 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO51787.1 - 1.8e-16 59.7 2.8 1.8e-16 59.7 1.9 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter DUF2348 PF09807.4 EGO51788.1 - 7.7e-10 38.2 0.1 5.1e-07 29.0 0.1 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) Arch_ATPase PF01637.13 EGO51788.1 - 0.0016 18.1 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EGO51788.1 - 0.033 14.1 0.1 0.061 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_L37e PF01907.14 EGO51789.1 - 2.5e-21 75.2 15.5 4.4e-13 48.8 1.5 2.3 2 0 0 2 2 2 2 Ribosomal protein L37e DZR PF12773.2 EGO51789.1 - 0.088 12.6 3.2 1.5 8.7 2.2 2.2 1 1 0 1 1 1 0 Double zinc ribbon FYVE PF01363.16 EGO51789.1 - 0.17 11.8 3.8 0.31 10.9 2.6 1.4 1 1 0 1 1 1 0 FYVE zinc finger zf-ribbon_3 PF13248.1 EGO51789.1 - 0.18 11.0 1.4 1.8 7.8 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain GFA PF04828.9 EGO51789.1 - 0.3 11.0 2.9 0.56 10.1 1.8 1.7 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EGO51789.1 - 0.61 9.8 3.4 17 5.2 0.4 2.4 2 0 0 2 2 2 0 Nudix N-terminal Ribosomal_S14 PF00253.16 EGO51789.1 - 1 8.8 9.7 3.3 7.1 0.8 2.6 2 1 0 2 2 2 0 Ribosomal protein S14p/S29e tRNA-synt_1 PF00133.17 EGO51790.1 - 4.8e-237 787.7 0.1 2.4e-236 785.4 0.1 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGO51790.1 - 5.9e-37 126.7 0.1 2.1e-36 125.0 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGO51790.1 - 1e-17 63.8 0.5 4.6e-05 22.2 0.0 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EGO51790.1 - 5.4e-14 51.9 0.5 9.4e-09 34.8 0.0 2.9 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EGO51790.1 - 0.0008 18.6 0.0 0.029 13.4 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.4 EGO51790.1 - 0.0021 18.1 5.7 0.0021 18.1 4.0 2.4 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm zf-RING_2 PF13639.1 EGO51791.1 - 2.6e-14 52.7 5.4 4.1e-14 52.1 3.7 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EGO51791.1 - 2e-12 46.6 0.0 4.2e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 EGO51791.1 - 3.7e-10 39.7 2.0 7.1e-10 38.8 1.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGO51791.1 - 1.5e-09 37.3 3.4 2.3e-09 36.7 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO51791.1 - 2.9e-09 36.8 5.1 4.7e-09 36.1 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO51791.1 - 7.2e-08 31.9 3.0 1.1e-07 31.4 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO51791.1 - 4.2e-07 29.5 2.4 6.5e-07 28.9 1.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGO51791.1 - 0.0015 18.3 2.3 0.0043 16.8 1.6 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EGO51791.1 - 0.026 14.4 2.6 0.066 13.1 1.8 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EGO51791.1 - 0.031 13.9 2.7 0.068 12.9 1.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGO51791.1 - 0.051 13.4 3.9 0.1 12.4 2.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EGO51791.1 - 0.06 13.4 4.0 0.13 12.3 2.8 1.6 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.3 EGO51791.1 - 0.17 11.4 1.8 0.3 10.6 1.2 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_RING PF05883.6 EGO51791.1 - 0.25 11.1 0.2 0.44 10.3 0.1 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 EGO51791.1 - 0.66 9.6 2.8 1.2 8.7 1.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EGO51791.1 - 0.99 9.1 2.5 1.8 8.3 1.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EGO51791.1 - 1.5 8.8 3.4 2.7 8.0 2.3 1.4 1 0 0 1 1 1 0 RING-like domain Apc5 PF12862.2 EGO51792.1 - 9.6e-32 108.7 3.2 9.6e-32 108.7 2.3 3.1 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_14 PF13428.1 EGO51792.1 - 5.2e-06 26.6 19.9 0.75 10.5 0.0 8.4 6 3 2 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO51792.1 - 0.00049 20.3 10.5 0.0081 16.4 0.1 4.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO51792.1 - 0.0024 17.7 21.8 10 6.1 0.6 6.6 4 1 3 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGO51792.1 - 0.11 12.3 5.5 12 5.9 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGO51792.1 - 3.7 7.6 10.7 1.2 9.1 0.1 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat COX6A PF02046.10 EGO51793.1 - 2.1e-46 156.6 1.7 2.2e-46 156.5 1.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos_2 PF14529.1 EGO51794.1 - 3.9e-16 58.7 0.0 1.1e-15 57.2 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EGO51794.1 - 4.2e-15 56.3 0.0 6.8e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 EGO51794.1 - 7.3e-05 22.6 1.5 0.00019 21.2 1.0 1.7 1 0 0 1 1 1 1 GRF zinc finger HMG_box PF00505.14 EGO51795.1 - 4.1e-18 65.4 0.0 6.5e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box DUF3431 PF11913.3 EGO51795.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3431) Maelstrom PF13017.1 EGO51796.1 - 0.15 11.4 0.3 0.61 9.5 0.0 1.9 2 0 0 2 2 2 0 piRNA pathway germ-plasm component MAT_Alpha1 PF04769.7 EGO51797.1 - 9.2e-80 266.7 0.0 1.2e-79 266.3 0.0 1.1 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 ANTH PF07651.11 EGO51799.1 - 1.8e-82 276.2 0.0 1.8e-82 276.2 0.0 2.7 4 0 0 4 4 4 1 ANTH domain I_LWEQ PF01608.12 EGO51799.1 - 3.2e-63 212.2 8.9 3.2e-63 212.2 6.2 5.6 5 2 2 7 7 7 1 I/LWEQ domain ENTH PF01417.15 EGO51799.1 - 0.00041 20.1 0.0 0.0018 18.1 0.0 2.2 1 0 0 1 1 1 1 ENTH domain Med15 PF09606.5 EGO51799.1 - 0.5 8.4 33.3 1 7.4 23.1 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Autophagy_N PF03986.8 EGO51800.1 - 1.1e-46 158.2 0.0 1.8e-46 157.5 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EGO51800.1 - 3.4e-22 78.3 0.5 2.8e-21 75.4 0.2 2.2 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EGO51800.1 - 1.9e-14 52.4 0.5 3.4e-14 51.6 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF3941 PF13081.1 EGO51800.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3941) QLQ PF08880.6 EGO51800.1 - 0.2 11.1 0.9 0.46 9.9 0.6 1.5 1 0 0 1 1 1 0 QLQ zf-CCCH PF00642.19 EGO51801.1 - 3.3e-08 33.0 2.0 7.1e-08 31.9 1.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.1 EGO51801.1 - 3.1e-07 29.9 6.0 5.3e-07 29.2 4.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGO51801.1 - 4.2e-07 29.8 8.0 7.3e-07 29.1 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO51801.1 - 4.3e-07 29.6 5.4 7.1e-07 28.9 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGO51801.1 - 6.2e-07 28.9 3.6 1e-06 28.2 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO51801.1 - 9.2e-06 25.2 5.5 1.7e-05 24.3 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGO51801.1 - 0.0018 17.9 2.0 0.0046 16.6 1.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGO51801.1 - 0.054 13.3 6.8 0.13 12.1 4.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGO51801.1 - 0.065 13.3 0.6 0.14 12.2 0.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Mcp5_PH PF12814.2 EGO51802.1 - 7e-43 145.4 0.0 1.5e-42 144.3 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Herpes_teg_N PF04843.7 EGO51802.1 - 0.046 13.1 0.0 0.15 11.4 0.1 1.8 2 0 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region DNA_pol_B PF00136.16 EGO51803.1 - 3.7e-96 322.7 0.0 6.2e-96 321.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EGO51803.1 - 6.4e-20 71.2 0.0 2.4e-10 39.8 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EGO51803.1 - 1.4e-17 63.4 0.4 3.9e-17 62.0 0.3 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Slu7 PF11708.3 EGO51804.1 - 2.3e-71 240.3 13.3 2.3e-71 240.3 9.2 1.5 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EGO51804.1 - 0.00042 19.9 0.2 0.00086 18.9 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO51804.1 - 0.00074 19.3 3.2 0.0013 18.6 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EGO51804.1 - 0.088 12.4 4.0 0.21 11.2 2.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_S4 PF00163.14 EGO51805.1 - 5.9e-28 97.1 0.9 1.1e-27 96.2 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EGO51805.1 - 2.5e-12 46.0 1.3 2.5e-12 46.0 0.9 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 EGO51806.1 - 3.6e-40 135.7 5.9 5.3e-40 135.2 4.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e DUF3865 PF12981.2 EGO51806.1 - 0.1 12.3 0.1 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) DUF2267 PF10025.4 EGO51806.1 - 0.11 12.5 0.4 0.2 11.7 0.3 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DUF2404 PF10296.4 EGO51807.1 - 1.6e-32 111.4 0.0 8.7e-32 109.1 0.0 2.1 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) ISN1 PF06437.6 EGO51808.1 - 3.5e-180 599.0 0.0 4.3e-180 598.7 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase HTH_17 PF12728.2 EGO51808.1 - 0.082 13.1 0.0 0.36 11.1 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain Reductase_C PF14759.1 EGO51809.1 - 0.12 12.6 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 Reductase C-terminal Prefoldin PF02996.12 EGO51809.1 - 0.14 11.7 2.7 0.24 11.0 1.9 1.3 1 0 0 1 1 1 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 EGO51809.1 - 0.51 10.0 10.5 3.1 7.5 7.3 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Pro_Al_protease PF02983.9 EGO51811.1 - 0.061 13.2 0.5 0.1 12.5 0.3 1.3 1 0 0 1 1 1 0 Alpha-lytic protease prodomain Pkinase PF00069.20 EGO51814.1 - 2.2e-54 184.3 0.0 3e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO51814.1 - 2e-25 89.3 0.0 4.9e-25 88.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO51814.1 - 0.0008 18.4 0.1 0.015 14.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGO51814.1 - 0.035 13.1 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IBN_N PF03810.14 EGO51815.1 - 5e-11 42.3 8.6 2.2e-10 40.2 0.1 4.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.5 EGO51815.1 - 9.2e-08 31.0 0.0 2.5e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.7 EGO51815.1 - 7.1e-06 25.9 9.1 0.00021 21.2 0.0 5.0 6 0 0 6 6 6 2 Exportin 1-like protein Katanin_con80 PF13925.1 EGO51815.1 - 0.00061 19.5 0.2 0.016 14.9 0.0 2.8 2 0 0 2 2 2 1 con80 domain of Katanin IMS PF00817.15 EGO51819.1 - 2.1e-45 154.1 0.0 4.1e-45 153.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGO51819.1 - 1.1e-14 54.4 0.0 2.6e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EGO51819.1 - 0.00033 20.5 0.0 0.00078 19.3 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif zf-C2H2_4 PF13894.1 EGO51819.1 - 0.034 14.4 0.3 0.11 12.9 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-DHHC PF01529.15 EGO51820.1 - 1.7e-28 99.2 7.1 1.7e-28 99.2 4.9 2.6 2 1 1 3 3 3 1 DHHC palmitoyltransferase 7tm_1 PF00001.16 EGO51820.1 - 0.0063 15.6 0.2 0.0063 15.6 0.1 2.4 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Med19 PF10278.4 EGO51820.1 - 0.29 10.7 4.1 13 5.4 2.6 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF805 PF05656.9 EGO51820.1 - 9.3 6.1 10.6 2.7 7.8 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Actino_peptide PF14408.1 EGO51821.1 - 0.039 13.8 10.0 0.066 13.1 5.4 2.1 2 0 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes PHD PF00628.24 EGO51821.1 - 0.044 13.4 4.7 1.9 8.2 0.1 2.2 2 0 0 2 2 2 0 PHD-finger Zn_Tnp_IS1595 PF12760.2 EGO51821.1 - 0.15 11.8 5.7 2.4 8.0 0.1 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF258 PF03193.11 EGO51821.1 - 0.16 11.1 0.6 0.2 10.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 zf-B_box PF00643.19 EGO51821.1 - 0.51 10.2 9.1 4.9 7.1 6.1 2.1 1 1 1 2 2 2 0 B-box zinc finger FYVE_2 PF02318.11 EGO51821.1 - 1.6 8.6 6.5 40 4.1 4.4 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger zf-C3HC4 PF00097.20 EGO51821.1 - 1.8 8.3 8.2 14 5.4 5.7 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 EGO51821.1 - 4.5 6.6 8.0 0.6 9.3 1.4 2.2 1 1 1 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EGO51821.1 - 5 6.8 10.7 0.12 12.0 0.6 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain SET PF00856.23 EGO51822.1 - 1.1e-17 64.8 0.7 7.1e-17 62.1 0.5 2.5 1 0 0 1 1 1 1 SET domain PAT1 PF09770.4 EGO51823.1 - 0.59 8.3 24.4 0.66 8.1 16.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 EGO51823.1 - 1.9 7.9 12.3 3.1 7.2 8.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.7 EGO51823.1 - 2.2 8.1 6.4 2.7 7.8 4.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SRP-alpha_N PF04086.8 EGO51823.1 - 2.2 7.6 7.4 2.7 7.2 5.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Evr1_Alr PF04777.8 EGO51824.1 - 0.091 12.6 0.1 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Erv1 / Alr family Apidaecin PF00807.12 EGO51824.1 - 0.35 10.5 5.7 0.76 9.5 3.9 1.5 1 0 0 1 1 1 0 Apidaecin Zn_clus PF00172.13 EGO51824.1 - 0.42 10.5 9.4 1 9.3 6.5 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.17 EGO51825.1 - 6.3e-18 64.0 0.1 8.2e-18 63.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain Pkinase PF00069.20 EGO51826.1 - 0.00023 20.3 0.0 0.00045 19.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain UBA_4 PF14555.1 EGO51827.1 - 6.1e-11 41.6 0.0 1.2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EGO51827.1 - 0.0043 17.0 0.0 0.0092 16.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain Methyltransf_24 PF13578.1 EGO51827.1 - 0.072 13.9 0.5 2.5 8.9 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain GAT PF03127.9 EGO51828.1 - 1.4e-19 69.9 1.0 3.4e-19 68.6 0.3 1.9 2 0 0 2 2 2 1 GAT domain VHS PF00790.14 EGO51828.1 - 0.00067 19.2 0.2 0.0079 15.8 0.0 2.3 2 1 0 2 2 2 1 VHS domain Serglycin PF04360.7 EGO51828.1 - 0.17 11.6 22.4 0.015 15.0 1.5 3.9 3 1 0 3 3 3 0 Serglycin F-box-like PF12937.2 EGO51829.1 - 1.8e-06 27.5 0.1 7.4e-06 25.6 0.0 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO51829.1 - 8.7e-05 22.0 1.3 0.00052 19.6 0.3 2.5 2 0 0 2 2 2 1 F-box domain Zn_clus PF00172.13 EGO51830.1 - 0.017 15.0 1.9 0.026 14.4 1.3 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 EGO51833.1 - 2.8e-19 69.4 0.1 3.8e-19 68.9 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO51833.1 - 1.3e-14 54.6 0.0 2.4e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO51833.1 - 6.7e-14 51.7 0.0 1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO51833.1 - 8e-14 51.8 0.0 2.3e-13 50.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO51833.1 - 2.7e-13 50.2 0.0 5.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO51833.1 - 8.1e-12 45.3 0.0 3.4e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO51833.1 - 4.7e-07 29.1 0.0 1.3e-06 27.7 0.0 1.7 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGO51833.1 - 1.3e-06 28.4 1.0 1.9e-06 27.9 0.2 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGO51833.1 - 0.00014 21.5 0.0 0.0003 20.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EGO51833.1 - 0.00058 19.0 0.1 0.0013 17.9 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EGO51833.1 - 0.0047 16.3 0.1 0.0079 15.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.6 EGO51833.1 - 0.023 14.1 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DREV PF05219.7 EGO51833.1 - 0.083 11.7 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.15 EGO51833.1 - 0.095 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase His_Phos_1 PF00300.17 EGO51834.1 - 8.3e-31 107.2 0.0 1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3716 PF12511.3 EGO51835.1 - 3.6e-09 36.0 9.5 7.5e-09 35.0 6.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Mucin PF01456.12 EGO51835.1 - 0.42 10.3 14.4 1.3 8.8 9.9 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein UCH PF00443.24 EGO51838.1 - 5.2e-54 183.1 0.0 6.7e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO51838.1 - 5.3e-22 78.6 0.0 9.6e-22 77.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EGO51838.1 - 3.9e-11 42.1 1.0 6.9e-11 41.3 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin family ARPC4 PF05856.7 EGO51839.1 - 3e-76 254.5 3.8 3.4e-76 254.3 2.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RRM_6 PF14259.1 EGO51840.1 - 1.5e-07 31.2 0.0 4.9e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO51840.1 - 1.3e-05 24.6 0.0 2.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.22 EGO51841.1 - 6.6e-76 250.1 2.8 3.7e-25 87.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein HP_OMP PF01856.12 EGO51841.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Helicobacter outer membrane protein PRP21_like_P PF12230.3 EGO51842.1 - 1.1e-58 198.5 14.9 1.4e-57 194.8 10.3 2.3 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EGO51842.1 - 4.9e-35 118.9 0.4 8.6e-17 60.5 0.0 2.5 2 0 0 2 2 2 2 Surp module PX PF00787.19 EGO51842.1 - 1.3e-23 82.9 0.4 3.1e-23 81.7 0.0 1.8 2 0 0 2 2 2 1 PX domain DivIVA PF05103.8 EGO51842.1 - 0.023 14.7 3.0 0.082 12.9 2.1 1.9 1 0 0 1 1 1 0 DivIVA protein Mod_r PF07200.8 EGO51842.1 - 0.19 11.6 4.4 0.068 13.0 0.9 1.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Med2 PF11214.3 EGO51842.1 - 0.24 11.4 2.2 0.94 9.5 1.5 2.0 1 0 0 1 1 1 0 Mediator complex subunit 2 PMT PF02366.13 EGO51843.1 - 1.9e-74 250.1 13.7 1.9e-74 250.1 9.5 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EGO51843.1 - 2.3e-57 193.6 0.0 2.3e-57 193.6 0.0 2.2 2 1 0 2 2 2 1 MIR domain DUF883 PF05957.8 EGO51843.1 - 3.1e-06 27.4 35.6 0.0056 17.0 8.3 3.6 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 EGO51843.1 - 4.3e-06 26.3 48.4 0.00017 21.1 20.7 2.3 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain YtxH PF12732.2 EGO51843.1 - 0.081 13.3 53.7 8.7e+02 0.3 0.7 5.3 1 1 2 3 3 3 0 YtxH-like protein LEA_4 PF02987.11 EGO51843.1 - 4.3 7.2 52.5 0.38 10.6 8.5 5.2 1 1 2 4 4 4 0 Late embryogenesis abundant protein MT0933_antitox PF14013.1 EGO51843.1 - 6.7 6.8 42.4 1.4e+02 2.7 9.2 4.8 1 1 2 3 3 3 0 MT0933-like antitoxin protein DUF948 PF06103.6 EGO51843.1 - 6.8 6.6 26.6 14 5.6 5.0 3.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.6 EGO51843.1 - 8.2 3.8 27.7 4.4 4.7 7.8 2.2 1 1 1 2 2 2 0 Prominin DUF1399 PF07173.7 EGO51845.1 - 1.7e-21 76.9 6.2 2.5e-17 63.4 0.2 3.1 2 1 0 3 3 3 2 Protein of unknown function (DUF1399) DUF1045 PF06299.7 EGO51845.1 - 0.066 12.8 0.1 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) Feld-I_B PF09252.5 EGO51847.1 - 0.0076 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 Allergen Fel d I-B chain TerB-N PF13208.1 EGO51848.1 - 0.076 12.4 3.1 0.17 11.2 2.2 1.5 1 0 0 1 1 1 0 TerB-N IncA PF04156.9 EGO51848.1 - 0.65 9.5 6.8 17 4.9 3.3 2.2 2 0 0 2 2 2 0 IncA protein RuBisCO_small PF00101.15 EGO51851.1 - 0.027 14.3 0.2 0.061 13.1 0.1 1.5 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain DUF1835 PF08874.5 EGO51857.1 - 0.054 13.4 0.1 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) DUF1899 PF08953.6 EGO51859.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) COG5 PF10392.4 EGO51861.1 - 0.049 13.5 0.1 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF1906 PF08924.6 EGO51861.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) DUF1572 PF07609.6 EGO51861.1 - 0.16 11.4 0.5 0.21 11.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) DUF4307 PF14155.1 EGO51864.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Glycophorin_A PF01102.13 EGO51864.1 - 0.092 12.5 1.9 0.21 11.3 0.6 2.2 2 1 0 2 2 2 0 Glycophorin A Deltaretro_Tax PF05599.6 EGO51864.1 - 0.75 10.1 7.1 0.18 12.1 1.7 2.3 2 0 0 2 2 2 0 Deltaretrovirus Tax protein Glyco_hydro_11 PF00457.12 EGO51865.1 - 3.2e-83 277.5 21.9 3.7e-83 277.3 15.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 zf-H2C2_2 PF13465.1 EGO51866.1 - 3.2e-05 23.9 1.2 3.2e-05 23.9 0.8 4.6 4 1 0 4 4 4 2 Zinc-finger double domain Zn_clus PF00172.13 EGO51866.1 - 7.2e-05 22.6 11.9 0.00021 21.1 8.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EGO51866.1 - 0.00071 19.7 6.0 0.00071 19.7 4.2 5.1 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO51866.1 - 0.0018 18.4 5.9 0.0018 18.4 4.1 4.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type CAF-1_p150 PF11600.3 EGO51866.1 - 0.21 10.9 41.5 0.61 9.4 26.2 2.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal p450 PF00067.17 EGO51867.1 - 6.2e-69 232.6 0.0 7.5e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EGO51869.1 - 3.1e-23 81.7 0.6 5.4e-23 80.9 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO51869.1 - 2.7e-20 72.1 0.4 9.5e-20 70.3 0.1 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EGO51869.1 - 0.045 13.7 0.2 0.077 13.0 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_11 PF08241.7 EGO51869.1 - 0.074 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Atg14 PF10186.4 EGO51871.1 - 4.5e-20 71.7 0.1 7.3e-20 71.1 0.1 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 SKG6 PF08693.5 EGO51871.1 - 0.00025 20.3 4.3 0.00056 19.1 3.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1191 PF06697.7 EGO51871.1 - 0.05 12.4 0.0 0.093 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DAP10 PF07213.6 EGO51871.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 DAP10 membrane protein Adeno_E3_CR2 PF02439.10 EGO51871.1 - 0.11 12.0 1.0 0.21 11.1 0.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 EGO51871.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cupin_4 PF08007.7 EGO51871.1 - 0.43 9.7 1.8 1.7 7.8 0.1 2.2 2 0 0 2 2 2 0 Cupin superfamily protein AAA PF00004.24 EGO51875.1 - 9.9e-41 139.0 0.0 1.7e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO51875.1 - 4.9e-06 26.7 0.0 0.00059 19.9 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EGO51875.1 - 2.2e-05 24.1 0.1 0.00024 20.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGO51875.1 - 0.00024 21.0 0.0 0.00071 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGO51875.1 - 0.00028 20.9 0.1 0.001 19.0 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain DUF815 PF05673.8 EGO51875.1 - 0.0017 17.3 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EGO51875.1 - 0.0051 17.6 0.1 0.013 16.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGO51875.1 - 0.0088 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGO51875.1 - 0.0093 15.7 0.1 0.021 14.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EGO51875.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 EGO51875.1 - 0.028 14.3 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGO51875.1 - 0.03 13.8 0.0 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGO51875.1 - 0.036 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGO51875.1 - 0.045 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EGO51875.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EGO51875.1 - 0.066 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EGO51875.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 EGO51875.1 - 0.095 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGO51875.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EGO51875.1 - 0.13 11.3 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EGO51875.1 - 0.15 11.4 0.2 0.42 9.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.19 EGO51876.1 - 2.9e-140 468.1 12.9 3.7e-140 467.7 8.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 EGO51876.1 - 0.021 14.2 0.0 0.078 12.4 0.0 1.9 1 0 0 1 1 1 0 Phage Tail Protein X DUF3924 PF13062.1 EGO51876.1 - 0.043 13.6 0.3 0.13 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) IBR PF01485.16 EGO51877.1 - 4.8 7.1 14.1 0.41 10.5 5.1 2.4 2 0 0 2 2 2 0 IBR domain RRM_1 PF00076.17 EGO51878.1 - 2.7e-19 68.5 0.4 1.9e-18 65.8 0.1 2.0 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO51878.1 - 3.5e-13 49.3 0.0 5.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO51878.1 - 1.7e-09 37.3 0.1 2.8e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3661 PF12400.3 EGO51879.1 - 5e-45 152.7 1.0 8e-45 152.0 0.7 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein K_channel_TID PF07941.6 EGO51880.1 - 0.0069 16.5 1.2 0.0069 16.5 0.8 2.8 2 1 0 2 2 2 1 Potassium channel Kv1.4 tandem inactivation domain ArfGap PF01412.13 EGO51881.1 - 3.6e-35 120.2 0.4 1.5e-34 118.2 0.0 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EGO51881.1 - 1.6e-12 47.5 0.0 4.2e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 PH domain PilJ PF13675.1 EGO51881.1 - 0.35 11.2 6.9 0.093 13.0 0.3 2.6 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term PMM PF03332.8 EGO51884.1 - 2.7e-102 341.0 0.0 3.1e-102 340.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EGO51884.1 - 3.3e-05 23.6 0.0 0.00011 21.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 EGO51884.1 - 0.07 12.0 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Trehalose-phosphatase DDOST_48kD PF03345.9 EGO51885.1 - 3.2e-167 556.3 0.0 3.6e-167 556.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta NADHdh_A3 PF14987.1 EGO51886.1 - 0.0024 17.7 0.3 0.0027 17.5 0.2 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 Beach PF02138.13 EGO51887.1 - 3.5e-111 370.9 0.0 6.1e-111 370.1 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EGO51887.1 - 5.7e-13 48.6 0.4 1.7e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 EGO51887.1 - 4.7e-10 39.9 0.0 1.2e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 EGO51887.1 - 1.3e-06 28.0 2.6 0.21 11.5 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Peptidase_S8 PF00082.17 EGO51889.1 - 2.5e-52 177.7 10.4 4.1e-52 177.0 7.2 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGO51889.1 - 9.4e-22 77.3 2.3 1.2e-21 77.0 0.3 2.1 2 0 0 2 2 2 1 Peptidase inhibitor I9 TryThrA_C PF12319.3 EGO51890.1 - 0.12 11.5 0.2 0.25 10.4 0.2 1.4 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal ATP12 PF07542.6 EGO51892.1 - 1.5e-31 108.8 0.1 2.7e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein AMP-binding PF00501.23 EGO51894.1 - 9.9e-77 258.0 0.0 1.3e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO51894.1 - 6e-17 62.3 0.2 3.5e-16 59.9 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pyridoxal_deC PF00282.14 EGO51895.1 - 8.3e-58 195.6 0.0 1.1e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EGO51895.1 - 0.00065 18.5 0.0 0.0013 17.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DUF1682 PF07946.9 EGO51895.1 - 0.022 13.6 0.1 0.037 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Glyco_transf_28 PF03033.15 EGO51896.1 - 1.4e-05 24.8 0.0 2.3e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain ParBc_2 PF08857.6 EGO51896.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative ParB-like nuclease FadA PF09403.5 EGO51897.1 - 0.074 13.0 0.1 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Adhesion protein FadA MmgE_PrpD PF03972.9 EGO51898.1 - 2.8e-148 493.8 0.0 3.3e-148 493.5 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family RabGAP-TBC PF00566.13 EGO51899.1 - 3e-45 154.3 0.0 4.4e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 EGO51899.1 - 2.1e-05 24.0 1.2 0.005 16.6 0.2 3.7 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.1 EGO51899.1 - 0.0025 17.9 0.0 0.03 14.4 0.0 2.6 1 1 1 2 2 2 1 EF-hand domain pair GRAM PF02893.15 EGO51899.1 - 0.0092 15.4 0.0 0.023 14.2 0.0 1.7 1 1 0 1 1 1 1 GRAM domain EF-hand_1 PF00036.27 EGO51899.1 - 0.0096 15.1 0.2 0.3 10.5 0.2 3.1 3 0 0 3 3 3 1 EF hand Pkinase PF00069.20 EGO51900.1 - 8e-66 221.8 0.0 1.1e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO51900.1 - 6.2e-30 104.1 0.0 9e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO51900.1 - 3.3e-06 26.2 0.0 4.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO51900.1 - 0.0021 17.8 0.3 0.14 11.8 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGO51900.1 - 0.0037 16.1 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Exo_endo_phos PF03372.18 EGO51901.1 - 5.4e-18 65.8 0.7 9.3e-17 61.7 0.5 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 EGO51902.1 - 1.4e-38 132.5 0.0 1.7e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO51902.1 - 7.5e-14 51.4 0.0 1.1e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO51902.1 - 1.4e-05 24.9 0.0 0.0014 18.3 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EGO51902.1 - 0.052 12.3 0.1 0.079 11.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pal1 PF08316.6 EGO51905.1 - 5.4e-46 156.5 1.0 5.4e-46 156.5 0.7 2.2 2 1 0 2 2 2 1 Pal1 cell morphology protein NT-C2 PF10358.4 EGO51907.1 - 1.1e-18 67.0 0.0 6.5e-14 51.6 0.0 2.2 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins POP1 PF06978.6 EGO51908.1 - 5.2e-67 225.1 17.7 5.2e-67 225.1 12.3 1.7 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EGO51908.1 - 5.6e-29 99.8 1.7 1.4e-28 98.5 0.0 2.4 2 0 0 2 2 2 1 POPLD (NUC188) domain IBR PF01485.16 EGO51909.1 - 4.4e-11 42.5 35.3 2.6e-07 30.4 5.2 4.1 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EGO51909.1 - 0.00045 19.9 10.3 0.00045 19.9 7.1 3.3 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EGO51909.1 - 0.00096 18.7 12.4 0.00096 18.7 8.6 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Synaptobrevin PF00957.16 EGO51909.1 - 0.0086 15.6 2.1 0.032 13.8 1.4 1.9 1 0 0 1 1 1 1 Synaptobrevin zf-RING_5 PF14634.1 EGO51909.1 - 0.014 15.1 10.9 0.014 15.1 7.6 3.5 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGO51909.1 - 1.3 8.8 14.4 0.1 12.3 5.2 2.6 2 0 0 2 2 2 0 RING-type zinc-finger HSP70 PF00012.15 EGO51910.1 - 4.1e-85 285.9 3.8 4.1e-85 285.9 2.6 2.2 2 1 1 3 3 3 1 Hsp70 protein MreB_Mbl PF06723.8 EGO51910.1 - 4.2e-07 28.8 0.1 7.8e-07 27.9 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein zf-C2H2_4 PF13894.1 EGO51912.1 - 0.00017 21.6 22.2 0.014 15.6 0.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO51912.1 - 0.0025 18.0 24.8 0.19 12.1 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type Adeno_E3_CR2 PF02439.10 EGO51912.1 - 0.055 13.0 0.2 0.099 12.2 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SH3_1 PF00018.23 EGO51913.1 - 8.5e-17 60.2 0.1 1.3e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGO51913.1 - 5.4e-10 38.6 0.1 8.3e-10 38.1 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGO51913.1 - 1.8e-09 36.9 0.0 3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain zf-C4H2 PF10146.4 EGO51913.1 - 0.00042 20.4 0.3 0.00042 20.4 0.2 2.1 1 1 0 2 2 2 1 Zinc finger-containing protein GRP PF07172.6 EGO51913.1 - 0.011 16.1 11.6 0.028 14.9 8.0 1.6 1 0 0 1 1 1 0 Glycine rich protein family PAT1 PF09770.4 EGO51913.1 - 4.2 5.4 7.6 6.6 4.8 5.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EGO51913.1 - 5.1 6.8 5.2 7 6.4 3.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ERM PF00769.14 EGO51914.1 - 0.00068 19.2 8.4 0.0012 18.4 5.8 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family AKNA PF12443.3 EGO51914.1 - 0.1 12.6 4.6 8.2 6.5 0.1 2.5 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF3138 PF11336.3 EGO51914.1 - 0.11 10.7 0.1 0.17 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) OmpH PF03938.9 EGO51914.1 - 1.1 9.2 7.0 1.9 8.4 4.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIVA PF05103.8 EGO51914.1 - 1.9 8.5 10.8 8.2 6.4 3.7 2.4 2 0 0 2 2 2 0 DivIVA protein DUF904 PF06005.7 EGO51914.1 - 5.1 7.4 11.1 2.6 8.3 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF904) WSC PF01822.14 EGO51916.1 - 1e-35 121.4 39.2 1.5e-19 69.7 5.7 4.1 4 0 0 4 4 4 3 WSC domain PAN_4 PF14295.1 EGO51916.1 - 8.4e-10 38.2 0.4 8.4e-10 38.2 0.3 6.2 5 2 2 7 7 7 2 PAN domain PAN_1 PF00024.21 EGO51916.1 - 0.043 13.5 0.0 0.043 13.5 0.0 5.5 5 2 1 6 6 6 0 PAN domain TYA PF01021.14 EGO51916.1 - 0.26 11.4 3.2 0.91 9.7 0.1 2.7 2 0 0 2 2 2 0 TYA transposon protein CorA PF01544.13 EGO51918.1 - 0.00019 20.5 2.7 0.0016 17.5 0.1 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Glyco_hydro_25 PF01183.15 EGO51920.1 - 1.7e-43 148.5 1.7 1.9e-43 148.3 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Sod_Cu PF00080.15 EGO51921.1 - 1.1e-14 54.7 0.0 1.4e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) YscW PF09619.5 EGO51921.1 - 0.027 14.1 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system lipoprotein chaperone (YscW) Ribosomal_L44 PF00935.14 EGO51923.1 - 4.5e-35 119.4 11.4 6.3e-35 119.0 7.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.6 EGO51923.1 - 0.13 12.1 5.6 0.1 12.4 0.4 2.2 1 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Ribosomal_L33 PF00471.15 EGO51923.1 - 1.2 9.4 6.1 1.5 9.0 0.3 2.6 2 0 0 2 2 2 0 Ribosomal protein L33 RRM_1 PF00076.17 EGO51924.1 - 9.8e-22 76.3 0.0 5.9e-12 45.0 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO51924.1 - 1.7e-18 66.3 0.0 3.4e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO51924.1 - 2.3e-16 59.3 0.0 2.4e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGO51924.1 - 0.013 15.2 0.0 6.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 C8 PF08742.6 EGO51925.1 - 0.002 18.3 0.5 0.002 18.3 0.4 2.0 1 1 1 2 2 2 1 C8 domain CFEM PF05730.6 EGO51925.1 - 0.69 9.7 4.1 1.6 8.6 2.8 1.6 1 1 0 1 1 1 0 CFEM domain Glyco_hydro_3 PF00933.16 EGO51926.1 - 4.2e-48 163.8 0.0 5.5e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO51926.1 - 3.5e-39 134.6 0.5 4.3e-38 131.0 0.3 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Esterase_phd PF10503.4 EGO51927.1 - 8.4e-27 93.8 0.4 1.7e-26 92.8 0.3 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 EGO51927.1 - 8e-13 47.8 13.7 8e-13 47.8 9.5 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 EGO51927.1 - 4.9e-10 38.9 1.4 8.2e-10 38.2 1.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO51927.1 - 3.5e-06 26.8 0.1 5.9e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGO51927.1 - 6.6e-06 25.7 0.7 1e-05 25.1 0.5 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 EGO51927.1 - 0.00056 19.8 0.0 0.0009 19.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EGO51927.1 - 0.004 15.9 0.7 0.0076 15.0 0.5 1.4 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.15 EGO51927.1 - 0.01 15.3 0.1 0.016 14.7 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EGO51927.1 - 0.012 15.2 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EGO51927.1 - 0.033 13.6 0.2 0.058 12.8 0.1 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase MFS_1 PF07690.11 EGO51928.1 - 3.4e-46 157.5 57.7 3.7e-45 154.1 39.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO51928.1 - 1.5e-20 72.9 19.7 2.1e-20 72.4 13.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGO51928.1 - 5.3e-18 64.8 3.1 5.3e-18 64.8 2.1 3.8 3 1 2 5 5 5 1 Sugar (and other) transporter Trypan_PARP PF05887.6 EGO51928.1 - 0.052 13.3 5.9 0.11 12.3 4.1 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HMG-CoA_red PF00368.13 EGO51929.1 - 7.8e-157 521.7 7.1 1e-156 521.2 5.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EGO51929.1 - 1.2e-42 145.2 2.2 2.2e-42 144.3 1.5 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EGO51929.1 - 3.8e-13 49.1 7.1 8.4e-12 44.8 4.9 2.4 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EGO51929.1 - 1.9e-06 26.1 3.4 1.9e-06 26.1 2.4 1.5 2 0 0 2 2 2 1 Patched family Lig_chan PF00060.21 EGO51929.1 - 0.044 13.4 2.5 1.5 8.5 0.0 2.6 2 0 0 2 2 2 0 Ligand-gated ion channel Dmrt1 PF12374.3 EGO51929.1 - 5.9 7.3 7.6 0.68 10.3 1.2 2.4 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Isochorismatase PF00857.15 EGO51930.1 - 3.6e-27 95.4 0.0 2.8e-25 89.2 0.0 2.1 1 1 0 1 1 1 1 Isochorismatase family zf-RING_2 PF13639.1 EGO51931.1 - 1.3e-13 50.4 2.3 2.5e-13 49.6 1.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO51931.1 - 3.4e-07 30.1 1.7 6e-07 29.3 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO51931.1 - 2e-06 27.3 0.3 4.2e-06 26.2 0.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO51931.1 - 0.00051 19.7 0.4 0.00092 18.8 0.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EGO51931.1 - 0.00064 19.7 3.5 0.0017 18.3 2.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGO51931.1 - 0.016 14.8 0.6 0.03 13.9 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Aldedh PF00171.17 EGO51932.1 - 1.1e-153 511.8 0.0 1.4e-153 511.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGO51932.1 - 6.5e-07 28.4 0.0 1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EGO51932.1 - 3.2e-05 23.2 0.0 0.14 11.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) DUF1212 PF06738.7 EGO51934.1 - 3.2e-55 186.5 3.0 6.3e-54 182.3 0.2 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EGO51934.1 - 4.4e-21 75.1 30.2 3.9e-14 52.6 1.4 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3815) DUF2301 PF10063.4 EGO51934.1 - 0.12 12.6 3.2 0.31 11.2 2.2 1.7 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) Amidoligase_2 PF12224.3 EGO51938.1 - 2.7e-18 66.4 1.2 3.8e-18 66.0 0.9 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme Ldh_1_N PF00056.18 EGO51939.1 - 8.3e-45 152.0 0.6 1.6e-44 151.1 0.4 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EGO51939.1 - 1.8e-32 112.4 0.1 3e-32 111.7 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 EGO51939.1 - 1.4e-05 24.5 2.1 0.0039 16.5 0.1 3.0 2 1 1 3 3 3 2 Family 4 glycosyl hydrolase Shikimate_DH PF01488.15 EGO51939.1 - 2.9e-05 24.1 0.2 0.00012 22.1 0.1 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGO51939.1 - 0.0023 17.3 0.9 0.0066 15.8 0.6 1.9 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 EGO51939.1 - 0.0033 17.2 0.1 0.0062 16.3 0.1 1.6 1 0 0 1 1 1 1 ThiF family DAO PF01266.19 EGO51939.1 - 0.0035 16.3 3.3 0.0053 15.6 2.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EGO51939.1 - 0.016 14.8 1.4 0.032 13.8 0.2 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 EGO51939.1 - 0.018 13.8 0.6 0.03 13.0 0.4 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Pyr_redox_2 PF07992.9 EGO51939.1 - 0.023 14.5 0.0 0.067 13.0 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EGO51939.1 - 0.024 14.8 0.3 0.06 13.5 0.2 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 EGO51939.1 - 0.027 14.4 0.5 0.079 12.9 0.3 1.9 1 1 1 2 2 2 0 TrkA-N domain Thi4 PF01946.12 EGO51939.1 - 0.035 13.1 0.4 0.092 11.8 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.1 EGO51939.1 - 0.036 14.1 0.9 0.12 12.4 0.2 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO51939.1 - 0.053 13.9 1.1 0.29 11.5 0.2 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EGO51939.1 - 0.1 12.0 1.4 0.43 10.0 0.5 2.3 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AA_permease PF00324.16 EGO51940.1 - 2.5e-123 411.9 39.4 3e-123 411.6 27.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO51940.1 - 1e-29 103.3 46.2 1.4e-29 102.8 32.0 1.1 1 0 0 1 1 1 1 Amino acid permease Amidohydro_3 PF07969.6 EGO51941.1 - 4.9e-48 164.3 2.8 7e-48 163.8 1.9 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGO51941.1 - 4.6e-09 35.9 0.0 1.6e-08 34.2 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EGO51941.1 - 0.00049 19.8 0.3 0.8 9.2 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family AP_endonuc_2 PF01261.19 EGO51941.1 - 0.0087 15.3 0.1 0.016 14.4 0.1 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Amidohydro_4 PF13147.1 EGO51941.1 - 0.24 11.3 8.4 1.4 8.8 0.1 3.3 3 1 0 3 3 3 0 Amidohydrolase zf-RING_2 PF13639.1 EGO51942.1 - 4.6e-08 32.7 4.7 4.6e-08 32.7 3.2 1.8 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.12 EGO51942.1 - 6.6e-05 22.2 0.1 0.00014 21.2 0.0 1.6 1 0 0 1 1 1 1 SWIM zinc finger FANCL_C PF11793.3 EGO51942.1 - 0.00036 20.4 4.5 0.00036 20.4 3.1 1.8 2 0 0 2 2 2 1 FANCL C-terminal domain PHD PF00628.24 EGO51942.1 - 0.0016 18.0 7.5 0.0031 17.1 5.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-rbx1 PF12678.2 EGO51942.1 - 0.0039 17.2 2.9 0.0039 17.2 2.0 1.7 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGO51942.1 - 0.014 15.4 5.6 0.037 14.0 3.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO51942.1 - 0.015 14.9 3.5 0.036 13.7 2.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO51942.1 - 0.015 14.9 5.3 0.015 14.9 3.7 2.0 2 0 0 2 2 2 0 zinc-RING finger domain RINGv PF12906.2 EGO51942.1 - 0.075 13.0 7.4 0.16 12.0 5.1 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EGO51942.1 - 0.12 11.9 6.1 0.27 10.8 4.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4293 PF14126.1 EGO51943.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) ENTH PF01417.15 EGO51944.1 - 1.5e-26 92.7 0.0 2.1e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EGO51944.1 - 0.069 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 ANTH domain Pro_isomerase PF00160.16 EGO51945.1 - 1.9e-41 141.8 0.1 2.4e-41 141.5 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_pol_Rpc34 PF05158.7 EGO51946.1 - 7.8e-134 445.9 0.0 9.5e-134 445.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.6 EGO51946.1 - 0.00053 20.3 0.0 2.2 8.7 0.0 3.5 3 1 0 3 3 3 1 Replication protein A C terminal HTH_34 PF13601.1 EGO51946.1 - 0.00072 19.5 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF188 PF02639.9 EGO51946.1 - 0.046 13.1 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 B-block_TFIIIC PF04182.7 EGO51946.1 - 0.052 13.3 0.0 0.43 10.4 0.0 2.4 3 0 0 3 3 3 0 B-block binding subunit of TFIIIC HTH_24 PF13412.1 EGO51946.1 - 0.096 12.0 0.0 0.35 10.2 0.0 2.0 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Ribosomal_S25 PF03297.10 EGO51946.1 - 0.097 12.7 0.6 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 S25 ribosomal protein MFS_1 PF07690.11 EGO51947.1 - 6.5e-33 113.9 26.3 8.6e-33 113.4 18.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily VirB8 PF04335.8 EGO51947.1 - 0.096 12.2 0.0 9.1 5.7 0.0 2.4 2 0 0 2 2 2 0 VirB8 protein GPI-anchored PF10342.4 EGO51948.1 - 2.2e-16 60.0 2.0 2.2e-16 60.0 1.4 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Fungal_trans PF04082.13 EGO51949.1 - 2.3e-08 33.2 0.2 3.6e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cut12 PF11500.3 EGO51949.1 - 1 9.0 2.4 2.2 7.9 1.7 1.5 1 0 0 1 1 1 0 Spindle pole body formation-associated protein p450 PF00067.17 EGO51950.1 - 6.7e-64 216.0 0.0 8.8e-64 215.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UBN2_3 PF14244.1 EGO51951.1 - 0.0014 18.1 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Glyco_hydro_67M PF07488.7 EGO51952.1 - 0.099 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 middle domain Peptidase_C48 PF02902.14 EGO51954.1 - 4.3e-15 55.9 0.1 5.5e-14 52.3 0.1 2.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SLX9 PF15341.1 EGO51955.1 - 5.5e-36 123.6 6.2 2.2e-35 121.7 4.3 1.9 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 Resolvase PF00239.16 EGO51955.1 - 0.0062 16.3 1.0 0.018 14.9 0.3 1.9 1 1 1 2 2 2 1 Resolvase, N terminal domain DUF4106 PF13388.1 EGO51955.1 - 0.25 10.2 6.3 0.33 9.8 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) ThiF PF00899.16 EGO51956.1 - 3.1e-39 133.9 0.0 4.5e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EGO51956.1 - 1.2e-15 56.8 1.0 6.8e-14 51.2 0.6 2.3 2 0 0 2 2 2 1 MoeZ/MoeB domain Rhodanese PF00581.15 EGO51956.1 - 1.1e-13 51.4 0.0 2.1e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EGO51956.1 - 0.00083 19.4 0.3 0.0069 16.4 0.1 2.2 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EGO51956.1 - 0.081 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Chromo PF00385.19 EGO51957.1 - 7.8e-09 35.0 3.3 1.7e-08 33.9 2.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SspB PF04386.8 EGO51957.1 - 0.099 12.2 4.2 0.18 11.3 0.0 2.9 3 0 0 3 3 3 0 Stringent starvation protein B DUF761 PF05553.6 EGO51960.1 - 0.04 13.2 1.5 0.093 12.1 0.3 2.2 2 0 0 2 2 2 0 Cotton fibre expressed protein NAD_Gly3P_dh_N PF01210.18 EGO51961.1 - 5.6e-46 156.1 0.1 1.4e-45 154.7 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EGO51961.1 - 2.6e-37 127.8 0.0 4.1e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus hDGE_amylase PF14701.1 EGO51962.1 - 2.4e-179 596.6 0.0 3.1e-179 596.2 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EGO51962.1 - 5.4e-113 377.4 0.1 1.1e-112 376.4 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EGO51962.1 - 1.3e-86 290.0 0.0 2e-86 289.4 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EGO51962.1 - 6.7e-27 93.1 0.2 1.7e-26 91.8 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EGO51962.1 - 0.00078 18.9 0.3 0.57 9.5 0.0 2.6 3 0 0 3 3 3 2 Alpha amylase, catalytic domain DUF2379 PF09543.5 EGO51962.1 - 0.16 11.9 0.1 0.47 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) TauE PF01925.14 EGO51963.1 - 0.00066 19.2 0.8 0.00092 18.7 0.6 1.3 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Epiglycanin_C PF14654.1 EGO51963.1 - 0.043 13.8 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region DUF4381 PF14316.1 EGO51963.1 - 0.072 13.1 0.3 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Pex14_N PF04695.8 EGO51964.1 - 0.17 11.9 3.3 0.19 11.7 2.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CAF-1_p150 PF11600.3 EGO51964.1 - 4.7 6.5 5.8 5.8 6.2 4.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF605 PF04652.11 EGO51967.1 - 3 7.1 11.0 4.1 6.7 7.6 1.2 1 0 0 1 1 1 0 Vta1 like Daxx PF03344.10 EGO51967.1 - 6 5.2 6.0 8 4.8 4.1 1.2 1 0 0 1 1 1 0 Daxx Family HLH PF00010.21 EGO51968.1 - 1.5e-12 46.9 0.1 2.9e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_S25 PF03297.10 EGO51968.1 - 0.0051 16.8 0.4 0.01 15.8 0.3 1.5 1 0 0 1 1 1 1 S25 ribosomal protein Ribonuc_red_2_N PF08471.5 EGO51969.1 - 0.072 13.1 0.1 0.089 12.8 0.1 1.2 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase RCC_reductase PF06405.6 EGO51969.1 - 0.13 11.1 0.1 0.14 11.0 0.0 1.0 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) Vps23_core PF09454.5 EGO51970.1 - 0.016 14.8 0.1 0.076 12.6 0.0 2.0 2 0 0 2 2 2 0 Vps23 core domain Tannase PF07519.6 EGO51971.1 - 2e-12 46.5 0.1 7.5e-12 44.7 0.1 1.7 1 1 0 1 1 1 1 Tannase and feruloyl esterase DUF3237 PF11578.3 EGO51972.1 - 1.1e-37 128.6 0.0 1.6e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 EGO51972.1 - 1.1e-06 28.2 6.3 0.0069 16.1 0.1 2.6 2 0 0 2 2 2 2 BED zinc finger DUF1431 PF07248.7 EGO51972.1 - 0.078 12.9 9.5 0.13 12.2 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1431) MFS_1 PF07690.11 EGO51973.1 - 2.4e-41 141.6 29.9 2.4e-41 141.6 20.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2178 PF09946.4 EGO51973.1 - 0.0023 17.6 0.4 0.0095 15.6 0.3 2.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2178) Vpu PF00558.14 EGO51973.1 - 0.0027 17.2 0.0 0.0086 15.6 0.0 1.8 1 0 0 1 1 1 1 Vpu protein Herpes_US9 PF06072.6 EGO51973.1 - 0.41 10.5 2.6 23 4.9 0.4 3.3 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 MatE PF01554.13 EGO51975.1 - 3.8e-49 166.4 27.5 4.3e-26 91.4 4.2 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EGO51975.1 - 0.0027 17.5 20.4 0.0039 16.9 5.1 3.2 2 1 0 2 2 2 2 Polysaccharide biosynthesis C-terminal domain DUF4360 PF14273.1 EGO51976.1 - 4.2e-21 75.4 0.9 5.5e-21 75.0 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Form_Nir_trans PF01226.12 EGO51977.1 - 4.9e-68 228.7 23.5 5.6e-68 228.5 16.3 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter CBP PF12192.3 EGO51977.1 - 0.038 13.9 3.1 0.96 9.4 0.0 2.4 2 0 0 2 2 2 0 Fungal calcium binding protein M_domain PF12938.2 EGO51980.1 - 2.6 7.7 22.2 0.1 12.4 9.6 2.5 1 1 0 2 2 2 0 M domain of GW182 COesterase PF00135.23 EGO51981.1 - 2.8e-90 303.5 0.1 4e-90 303.0 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO51981.1 - 4.3e-05 23.1 0.2 8.3e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO51981.1 - 0.0031 16.7 0.5 0.005 16.0 0.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family F_actin_cap_B PF01115.12 EGO51981.1 - 0.024 13.8 0.1 0.039 13.1 0.1 1.2 1 0 0 1 1 1 0 F-actin capping protein, beta subunit Abhydrolase_5 PF12695.2 EGO51981.1 - 0.036 13.8 0.1 0.064 12.9 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family YobH PF13996.1 EGO51981.1 - 0.059 13.3 0.3 2.6 8.0 0.0 2.5 2 1 0 2 2 2 0 YobH-like protein Cellulase PF00150.13 EGO51982.1 - 2.3e-51 174.6 3.6 3.2e-51 174.1 2.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EGO51982.1 - 4.6e-11 42.1 15.0 4.6e-11 42.1 10.4 2.8 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EGO51982.1 - 0.92 9.6 3.9 1.9 8.5 2.7 1.5 1 0 0 1 1 1 0 Toxin 7 Pkinase_Tyr PF07714.12 EGO51983.1 - 5.5e-06 25.6 0.1 0.071 12.1 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EGO51983.1 - 0.0001 21.5 0.1 0.013 14.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Nucleoplasmin PF03066.10 EGO51984.1 - 0.24 10.8 18.7 0.25 10.8 12.9 1.1 1 0 0 1 1 1 0 Nucleoplasmin RNA_pol_Rpc4 PF05132.9 EGO51984.1 - 0.48 10.4 5.7 0.59 10.1 4.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Senescence_reg PF04520.8 EGO51984.1 - 0.6 10.5 4.1 0.64 10.4 2.8 1.1 1 0 0 1 1 1 0 Senescence regulator DUF1676 PF07898.8 EGO51984.1 - 1.2 9.4 5.4 1.4 9.2 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) RXT2_N PF08595.6 EGO51984.1 - 1.4 8.7 8.9 1.4 8.7 6.2 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 EGO51984.1 - 1.5 8.3 12.8 1.5 8.3 8.9 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1840 PF08895.6 EGO51984.1 - 1.8 8.6 4.7 1.9 8.5 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Prothymosin PF03247.9 EGO51984.1 - 2 8.6 27.7 2.3 8.4 19.2 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family BMF PF15185.1 EGO51984.1 - 2.2 7.5 10.8 2.6 7.3 7.5 1.0 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis Tim54 PF11711.3 EGO51984.1 - 2.3 6.7 6.0 2.2 6.7 4.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spore_coat_CotO PF14153.1 EGO51984.1 - 2.6 7.4 10.7 2.7 7.3 7.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO VID27 PF08553.5 EGO51984.1 - 2.7 6.1 14.4 2.8 6.0 10.0 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF1510 PF07423.6 EGO51984.1 - 2.8 7.2 11.1 3.1 7.1 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Voldacs PF03517.8 EGO51984.1 - 3.1 7.6 9.0 3.4 7.5 6.3 1.2 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling BSP_II PF05432.6 EGO51984.1 - 3.2 6.9 22.3 3.5 6.8 15.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) LIN37 PF15306.1 EGO51984.1 - 3.4 7.6 6.8 3.7 7.5 4.7 1.1 1 0 0 1 1 1 0 LIN37 FAM176 PF14851.1 EGO51984.1 - 3.4 7.3 9.9 3.8 7.1 6.8 1.1 1 0 0 1 1 1 0 FAM176 family Daxx PF03344.10 EGO51984.1 - 4 5.8 18.6 4 5.8 12.9 1.0 1 0 0 1 1 1 0 Daxx Family Adeno_terminal PF02459.10 EGO51984.1 - 4.8 5.2 10.6 4.2 5.4 7.4 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Med17 PF10156.4 EGO51984.1 - 5 5.2 8.8 5 5.2 6.1 1.0 1 0 0 1 1 1 0 Subunit 17 of Mediator complex OAD_gamma PF04277.8 EGO51984.1 - 6.1 7.2 6.0 6.7 7.1 4.1 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain YqfQ PF14181.1 EGO51984.1 - 6.7 6.7 7.9 7.5 6.5 5.5 1.1 1 0 0 1 1 1 0 YqfQ-like protein SspB PF04386.8 EGO51984.1 - 7.4 6.1 8.5 8.6 5.9 5.9 1.1 1 0 0 1 1 1 0 Stringent starvation protein B CENP-B_dimeris PF09026.5 EGO51984.1 - 7.6 6.8 21.7 9 6.6 15.0 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 EGO51984.1 - 8.7 5.5 9.9 8.6 5.5 6.9 1.0 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 EGO51984.1 - 9.6 6.5 10.8 11 6.3 7.5 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AA_permease_2 PF13520.1 EGO51987.1 - 2.3e-56 191.1 46.1 2.9e-56 190.8 31.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO51987.1 - 1.3e-15 56.7 41.2 1.9e-15 56.1 28.5 1.2 1 0 0 1 1 1 1 Amino acid permease SseC PF04888.7 EGO51988.1 - 0.0049 16.2 5.9 0.011 15.1 4.1 1.5 1 1 0 1 1 1 1 Secretion system effector C (SseC) like family Vfa1 PF08432.5 EGO51988.1 - 2.1 8.3 12.0 0.45 10.5 2.1 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF913 PF06025.7 EGO51988.1 - 5.6 5.6 5.7 3 6.4 2.6 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) PLAC8 PF04749.12 EGO51990.1 - 0.93 10.0 5.5 2.3 8.8 3.5 1.9 1 1 0 1 1 1 0 PLAC8 family RRM_1 PF00076.17 EGO51991.1 - 5e-46 154.2 0.0 2e-16 59.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO51991.1 - 7.3e-25 86.7 0.0 7.9e-10 38.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO51991.1 - 5.4e-23 80.6 0.0 1.6e-08 34.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGO51991.1 - 1.3e-06 28.0 0.1 0.0043 16.8 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EGO51991.1 - 1.4e-06 28.0 0.0 0.00019 21.2 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif 7TM_GPCR_Srab PF10292.4 EGO51992.1 - 0.16 10.6 0.2 0.21 10.2 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor Ecm29 PF13001.2 EGO51993.1 - 2.6e-141 471.5 0.0 5.7e-141 470.4 0.0 1.6 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 EGO51993.1 - 0.0011 18.9 12.4 0.3 11.2 0.0 8.3 11 0 0 11 11 11 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EGO51993.1 - 0.0021 18.4 0.1 0.31 11.4 0.0 3.9 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Thioredoxin_7 PF13899.1 EGO51994.1 - 2.5e-15 56.2 0.1 5.2e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 EGO51994.1 - 5e-13 48.3 0.5 1e-12 47.3 0.4 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EGO51994.1 - 5.5e-07 29.5 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.10 EGO51994.1 - 0.007 16.1 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Pkinase PF00069.20 EGO51995.1 - 1.6e-66 224.1 0.3 5.6e-66 222.3 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO51995.1 - 1.6e-47 161.7 0.0 3.4e-47 160.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Iso_dh PF00180.15 EGO51998.1 - 1.4e-81 274.1 0.0 1.8e-81 273.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Tyrosinase PF00264.15 EGO51999.1 - 1.7e-57 195.1 0.3 1.7e-57 195.1 0.2 1.9 2 0 0 2 2 2 1 Common central domain of tyrosinase WBS_methylT PF12589.3 EGO52000.1 - 8.4e-17 61.4 5.9 1.7e-16 60.4 4.1 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EGO52000.1 - 5.8e-12 45.9 0.0 1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO52000.1 - 5.9e-08 32.9 0.0 1.3e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO52000.1 - 2.6e-07 30.3 0.0 3.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO52000.1 - 1.3e-05 25.0 0.0 1.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO52000.1 - 1.9e-05 25.0 0.0 6.1e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGO52000.1 - 7.5e-05 22.3 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EGO52000.1 - 9.1e-05 23.0 0.0 0.0002 21.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO52000.1 - 9.4e-05 22.4 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGO52000.1 - 0.0026 16.8 0.0 0.084 11.9 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EGO52000.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Erv26 PF04148.8 EGO52001.1 - 6.4e-91 303.4 0.4 7.1e-91 303.2 0.2 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 QueT PF06177.6 EGO52001.1 - 0.019 14.9 2.0 0.039 13.9 1.4 1.5 1 0 0 1 1 1 0 QueT transporter Claudin_2 PF13903.1 EGO52001.1 - 2.1 8.0 6.6 1.3 8.6 2.8 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction 2-Hacid_dh_C PF02826.14 EGO52004.1 - 4.5e-58 195.3 0.0 6.1e-58 194.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGO52004.1 - 1.7e-27 95.4 0.0 2.3e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGO52004.1 - 1e-06 28.7 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EGO52004.1 - 0.004 17.0 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Oxidored_nitro PF00148.14 EGO52004.1 - 0.018 13.7 0.0 0.022 13.4 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase IlvN PF07991.7 EGO52004.1 - 0.074 12.4 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 EGO52004.1 - 0.19 11.8 0.5 3.1 7.9 0.4 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase RRM PF10378.4 EGO52005.1 - 0.067 12.7 1.9 0.34 10.5 1.3 2.2 1 1 1 2 2 2 0 Putative RRM domain MFS_1 PF07690.11 EGO52006.1 - 2.8e-34 118.3 27.9 2.8e-34 118.3 19.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2970 PF11174.3 EGO52006.1 - 2.1 8.0 8.6 0.54 9.8 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) FMO-like PF00743.14 EGO52008.1 - 4.9e-20 71.2 0.0 6.1e-19 67.6 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGO52008.1 - 2.5e-13 50.5 0.0 1.2e-12 48.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO52008.1 - 4.1e-12 46.1 0.2 4.7e-10 39.4 0.0 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGO52008.1 - 1.1e-11 44.5 0.0 4e-10 39.5 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO52008.1 - 3.2e-09 36.9 0.0 1.3e-08 34.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO52008.1 - 6e-09 35.2 0.4 1.2e-06 27.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 EGO52008.1 - 2.3e-07 30.2 0.0 0.00014 21.1 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 EGO52008.1 - 1.3e-05 24.3 0.0 0.001 18.0 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGO52008.1 - 0.00036 20.8 0.2 1.1 9.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO52008.1 - 0.00062 18.9 0.4 0.0016 17.5 0.0 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EGO52008.1 - 0.0022 16.5 0.2 0.02 13.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.9 EGO52008.1 - 0.016 13.8 0.1 0.33 9.5 0.0 2.4 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.14 EGO52008.1 - 0.021 13.9 0.0 0.045 12.7 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EGO52008.1 - 0.15 10.8 0.2 4.3 6.0 0.0 2.3 2 1 0 2 2 2 0 Glucose inhibited division protein A 7tm_2 PF00002.19 EGO52009.1 - 2.9e-10 39.6 9.2 2.9e-10 39.6 6.4 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EGO52009.1 - 1.4e-08 34.0 7.6 2.4e-08 33.2 5.3 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.3 EGO52009.1 - 0.00078 19.0 9.5 0.0015 18.1 6.6 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DUF3669 PF12417.3 EGO52010.1 - 2.6e-24 84.7 0.4 1.6e-22 78.9 0.1 2.3 2 0 0 2 2 2 2 Zinc finger protein Dynamin_N PF00350.18 EGO52011.1 - 1.6e-30 106.1 0.0 3.6e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGO52011.1 - 4.4e-10 38.8 0.0 8.5e-10 37.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EGO52011.1 - 0.00022 21.1 0.0 0.0011 18.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGO52011.1 - 0.0064 16.9 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 EGO52011.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGO52011.1 - 0.13 12.5 0.0 0.59 10.4 0.0 2.1 1 0 0 1 1 1 0 ABC transporter Apolipoprotein PF01442.13 EGO52011.1 - 4.1 6.8 9.6 2 7.8 0.1 3.2 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain DUF221 PF02714.10 EGO52012.1 - 6.5e-92 307.8 19.6 6.5e-92 307.8 13.6 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGO52012.1 - 4.4e-39 133.5 2.0 4.4e-39 133.5 1.4 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EGO52012.1 - 3.3e-18 65.9 0.0 6.6e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EGO52012.1 - 0.0041 17.0 0.0 3.6 7.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MutS_V PF00488.16 EGO52013.1 - 1e-63 214.8 0.6 2.4e-61 207.1 0.3 2.2 1 1 1 2 2 2 2 MutS domain V MutS_III PF05192.13 EGO52013.1 - 1.8e-14 54.0 0.7 2.9e-14 53.3 0.5 1.3 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EGO52013.1 - 0.0011 19.0 0.1 0.0039 17.2 0.0 1.9 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 EGO52013.1 - 0.031 13.7 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain K_trans PF02705.11 EGO52014.1 - 3.6e-177 589.9 16.6 4.3e-177 589.7 11.5 1.0 1 0 0 1 1 1 1 K+ potassium transporter Aminotran_4 PF01063.14 EGO52016.1 - 1.6e-23 83.4 0.0 2e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Glyco_transf_20 PF00982.16 EGO52017.1 - 4e-165 549.8 0.0 5.5e-165 549.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EGO52017.1 - 4.2e-41 140.3 0.0 6.9e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase WD40 PF00400.27 EGO52018.1 - 1.3e-75 246.7 20.9 2.8e-14 52.3 0.2 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EGO52018.1 - 2.7e-07 30.5 0.1 0.00075 19.2 0.0 3.7 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGO52018.1 - 8.5e-05 20.8 7.5 0.036 12.2 0.1 5.2 3 3 3 6 6 6 1 Nucleoporin Nup120/160 NLE PF08154.7 EGO52018.1 - 0.0057 16.6 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain DinB PF05163.7 EGO52018.1 - 0.032 13.9 0.0 0.072 12.7 0.0 1.5 2 0 0 2 2 2 0 DinB family Na_Ca_ex PF01699.19 EGO52019.1 - 4.9e-40 136.3 29.2 2e-23 82.5 8.2 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF917 PF06032.7 EGO52020.1 - 1.8e-108 362.2 1.1 2.8e-108 361.6 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EGO52020.1 - 5.4e-48 163.5 2.9 2.1e-46 158.3 0.7 3.2 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EGO52020.1 - 1.8e-25 89.4 0.1 9.3e-23 80.6 0.0 3.0 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EGO52020.1 - 0.0032 15.8 0.7 0.12 10.6 0.0 2.4 2 0 0 2 2 2 2 MutL protein StbA PF06406.6 EGO52020.1 - 0.11 11.3 0.7 1.5 7.7 0.1 2.4 2 0 0 2 2 2 0 StbA protein Epimerase PF01370.16 EGO52021.1 - 4.6e-08 32.7 0.0 6.4e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO52021.1 - 3.2e-06 27.2 0.2 9.1e-06 25.7 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGO52021.1 - 0.00025 19.8 0.0 0.00036 19.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EGO52021.1 - 0.028 13.6 0.1 0.045 12.9 0.1 1.4 1 1 0 1 1 1 0 NmrA-like family S-methyl_trans PF02574.11 EGO52023.1 - 4.6e-36 124.6 0.0 5.9e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pkinase PF00069.20 EGO52024.1 - 1.7e-07 30.6 0.0 1.2e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Sugar_tr PF00083.19 EGO52027.1 - 4.4e-79 266.1 23.7 1.1e-78 264.8 16.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO52027.1 - 9.5e-28 96.9 35.8 4.4e-27 94.7 22.4 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGO52027.1 - 0.00015 20.3 5.9 0.00015 20.3 4.1 3.6 3 1 0 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 EGO52027.1 - 0.31 9.1 9.3 0.016 13.3 0.6 2.4 3 0 0 3 3 3 0 Transmembrane secretion effector DUF1228 PF06779.9 EGO52027.1 - 1.6 8.7 7.1 7.8 6.6 0.5 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) YL1 PF05764.8 EGO52028.1 - 0.049 13.2 2.4 0.079 12.5 1.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Kinocilin PF15033.1 EGO52029.1 - 0.032 13.7 0.6 0.065 12.7 0.4 1.4 1 0 0 1 1 1 0 Kinocilin protein FtsX PF02687.16 EGO52029.1 - 1.1 9.0 21.3 0.17 11.6 3.1 3.8 2 1 1 3 3 3 0 FtsX-like permease family MFS_1 PF07690.11 EGO52030.1 - 1.8e-30 105.8 25.9 1.8e-30 105.8 18.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2205 PF10224.4 EGO52033.1 - 8.9e-34 114.9 1.1 1.2e-33 114.5 0.7 1.2 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Myosin_tail_1 PF01576.14 EGO52033.1 - 0.0078 14.0 1.9 0.0097 13.6 1.3 1.0 1 0 0 1 1 1 1 Myosin tail AAA_32 PF13654.1 EGO52033.1 - 0.021 13.5 0.1 0.026 13.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain TACC PF05010.9 EGO52033.1 - 0.023 14.4 0.2 0.034 13.9 0.2 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DivIC PF04977.10 EGO52033.1 - 0.4 10.2 2.7 3.6 7.1 1.6 2.1 1 1 1 2 2 2 0 Septum formation initiator Fungal_trans PF04082.13 EGO52035.1 - 6.5e-13 48.1 1.1 1.1e-12 47.4 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO52035.1 - 0.0089 15.9 1.5 0.016 15.0 1.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EGO52036.1 - 1.1e-90 304.3 18.9 1.3e-90 304.1 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO52036.1 - 1.9e-29 102.5 39.4 1.8e-28 99.2 14.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_2_C PF02836.12 EGO52038.1 - 2.5e-105 351.6 0.0 3.5e-105 351.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 EGO52038.1 - 1.2e-57 195.1 0.0 1.9e-57 194.4 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 EGO52038.1 - 4e-52 176.1 0.3 7.4e-52 175.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EGO52038.1 - 7.2e-13 48.9 0.2 1.5e-12 47.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 RNase_PH PF01138.16 EGO52040.1 - 8.1e-37 126.4 0.1 1.3e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Thioredoxin PF00085.15 EGO52041.1 - 1.1e-30 105.4 0.0 6.1e-25 86.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EGO52041.1 - 2.3e-06 27.5 0.0 0.00013 21.8 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EGO52041.1 - 2.9e-06 27.4 2.4 0.0017 18.4 0.1 3.1 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGO52041.1 - 5.7e-06 26.3 0.1 0.0011 19.0 0.0 3.6 3 2 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EGO52041.1 - 0.0044 17.0 0.0 0.0099 15.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EGO52041.1 - 0.0048 16.5 0.0 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EGO52041.1 - 0.018 14.6 0.0 0.081 12.4 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin DUF605 PF04652.11 EGO52042.1 - 1.6e-110 370.0 10.6 2e-110 369.7 7.4 1.0 1 0 0 1 1 1 1 Vta1 like Sua5_yciO_yrdC PF01300.13 EGO52045.1 - 0.017 14.3 0.0 0.5 9.6 0.0 2.3 2 0 0 2 2 2 0 Telomere recombination Sugar_tr PF00083.19 EGO52046.1 - 3.5e-109 365.3 24.3 4.1e-109 365.1 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO52046.1 - 6.7e-27 94.1 28.8 1.9e-19 69.6 5.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGO52046.1 - 2.9e-06 25.9 10.9 7.9e-05 21.2 1.2 3.1 4 0 0 4 4 4 2 MFS/sugar transport protein OATP PF03137.15 EGO52046.1 - 0.0068 14.5 1.7 0.0068 14.5 1.2 2.8 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family E1_DerP2_DerF2 PF02221.10 EGO52047.1 - 0.055 13.7 1.2 0.18 12.0 0.0 2.4 3 0 0 3 3 3 0 ML domain DUF4414 PF14377.1 EGO52048.1 - 0.016 15.1 4.1 0.059 13.2 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) Polysacc_deac_1 PF01522.16 EGO52048.1 - 0.055 13.0 0.4 0.24 11.0 0.4 1.8 2 0 0 2 2 2 0 Polysaccharide deacetylase Suf PF05843.9 EGO52048.1 - 0.14 11.8 4.3 7.6 6.1 1.6 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Dicistro_VP4 PF11492.3 EGO52048.1 - 0.34 10.9 4.1 10 6.1 0.1 2.8 2 1 0 2 2 2 0 Cricket paralysis virus, VP4 JAB PF01398.16 EGO52050.1 - 2.2e-34 117.6 0.0 4e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EGO52050.1 - 2.3e-25 88.9 1.8 2.4e-25 88.8 0.4 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EGO52050.1 - 2.2e-08 33.6 0.0 3.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Hist_deacetyl PF00850.14 EGO52051.1 - 2.1e-73 247.3 0.2 3.8e-73 246.5 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain DUF1311 PF07007.7 EGO52051.1 - 0.097 12.7 2.3 0.2 11.7 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) Abhydrolase_4 PF08386.5 EGO52052.1 - 3.8e-23 81.3 0.0 8.9e-23 80.1 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EGO52052.1 - 4.6e-15 55.7 0.0 1.5e-12 47.5 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGO52052.1 - 9e-12 45.3 1.7 1.5e-07 31.5 0.1 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO52052.1 - 0.0021 17.8 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Tim17 PF02466.14 EGO52055.1 - 3.9e-30 104.5 0.3 5.3e-30 104.0 0.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family NAD_binding_6 PF08030.7 EGO52056.1 - 1e-19 70.9 0.0 1.6e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EGO52056.1 - 1.4e-19 70.4 14.4 2.8e-19 69.4 10.0 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EGO52056.1 - 1.3e-11 44.2 0.0 3.5e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 EGO52056.1 - 1.1e-06 29.1 0.0 2.1e-05 25.0 0.0 2.4 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain Sdh_cyt PF01127.17 EGO52056.1 - 0.013 15.2 8.8 0.034 13.9 4.1 2.6 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4018 PF13210.1 EGO52056.1 - 5.6 6.3 11.9 0.12 11.7 3.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4018) Ctr PF04145.10 EGO52057.1 - 5.3e-44 149.7 3.4 6.4e-44 149.5 2.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF204 PF02659.10 EGO52057.1 - 1.6 8.9 8.0 2.8 8.1 0.7 3.1 2 1 1 3 3 3 0 Domain of unknown function DUF Peptidase_S28 PF05577.7 EGO52058.1 - 1.3e-52 178.8 0.1 2.2e-52 178.1 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DUF4231 PF14015.1 EGO52060.1 - 0.44 10.5 2.5 0.88 9.5 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) HMG_box_2 PF09011.5 EGO52061.1 - 1.2e-26 92.8 28.8 0.0028 17.9 0.0 9.4 9 0 0 9 9 9 8 HMG-box domain HMG_box PF00505.14 EGO52061.1 - 4.3e-21 74.9 26.0 0.00012 22.2 0.0 9.7 10 0 0 10 10 10 8 HMG (high mobility group) box MFS_1 PF07690.11 EGO52062.1 - 3.7e-13 48.9 36.1 3.8e-08 32.4 11.3 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Phage_holin_1 PF04531.8 EGO52062.1 - 7.8 6.6 6.3 7.5 6.7 0.2 3.5 4 0 0 4 4 4 0 Bacteriophage holin VSP PF03302.8 EGO52063.1 - 9.5e-05 21.1 0.1 9.5e-05 21.1 0.1 2.1 2 0 0 2 2 2 1 Giardia variant-specific surface protein MtrF PF09472.5 EGO52063.1 - 0.44 9.8 3.9 0.83 8.9 2.7 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Glyco_hydro_61 PF03443.9 EGO52064.1 - 6.9e-45 153.5 0.3 1e-44 152.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EGO52064.1 - 5.4e-12 45.1 13.6 5.4e-12 45.1 9.4 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Serglycin PF04360.7 EGO52064.1 - 0.018 14.8 2.1 0.018 14.8 1.5 1.8 2 0 0 2 2 2 0 Serglycin 6PGD PF00393.14 EGO52065.1 - 7.1e-56 189.5 0.1 5.7e-54 183.2 0.0 2.1 1 1 1 2 2 2 2 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EGO52065.1 - 6.2e-22 78.1 0.0 1.1e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_18 PF12847.2 EGO52065.1 - 0.029 14.9 0.0 0.09 13.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain NAD_binding_11 PF14833.1 EGO52065.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase AP_endonuc_2 PF01261.19 EGO52066.1 - 5.1e-41 140.2 0.0 8.7e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Ribosomal_S17e PF00833.13 EGO52067.1 - 0.036 13.8 0.8 0.059 13.1 0.1 1.7 2 0 0 2 2 2 0 Ribosomal S17 Prenyltrans PF00432.16 EGO52069.1 - 0.085 12.4 1.8 15 5.2 0.0 2.3 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Formyl_trans_N PF00551.14 EGO52070.1 - 3.4e-36 124.4 0.0 4.6e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase DUF2336 PF10098.4 EGO52070.1 - 0.00016 21.0 0.0 0.00027 20.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2336) MannoseP_isomer PF01050.13 EGO52070.1 - 0.1 12.2 0.1 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase DUF1917 PF08939.5 EGO52073.1 - 6.9e-47 160.2 0.0 6.9e-47 160.2 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF1917) SBP_bac_8 PF13416.1 EGO52076.1 - 0.042 13.5 0.2 0.062 13.0 0.1 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Arif-1 PF06770.6 EGO52077.1 - 0.19 11.1 2.8 0.41 9.9 1.9 1.5 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) AMP-binding PF00501.23 EGO52078.1 - 0.0042 15.5 0.0 1.4 7.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme bZIP_1 PF00170.16 EGO52080.1 - 0.001 18.9 23.7 0.013 15.4 0.7 4.4 4 1 1 5 5 5 2 bZIP transcription factor DivIC PF04977.10 EGO52080.1 - 0.0023 17.3 21.2 0.0063 15.9 3.8 3.9 3 1 1 4 4 4 2 Septum formation initiator Syntaxin PF00804.20 EGO52080.1 - 0.0095 16.0 10.1 0.042 14.0 5.5 2.3 2 0 0 2 2 2 1 Syntaxin DUF904 PF06005.7 EGO52080.1 - 0.025 14.8 22.7 2.6 8.3 3.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Mnd1 PF03962.10 EGO52080.1 - 0.038 13.6 16.7 0.084 12.5 2.5 2.3 1 1 1 2 2 2 0 Mnd1 family FRQ PF09421.5 EGO52080.1 - 0.049 11.4 1.2 0.056 11.2 0.8 1.1 1 0 0 1 1 1 0 Frequency clock protein TSC22 PF01166.13 EGO52080.1 - 0.22 11.5 14.5 0.34 10.9 0.7 4.3 3 1 1 4 4 4 0 TSC-22/dip/bun family IncA PF04156.9 EGO52080.1 - 0.84 9.2 16.8 2.9 7.4 11.7 1.9 1 1 0 1 1 1 0 IncA protein AAA_13 PF13166.1 EGO52080.1 - 1.3 7.3 14.6 2.2 6.6 10.0 1.5 1 1 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 EGO52080.1 - 1.4 8.7 24.3 11 5.9 1.2 4.3 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.4 EGO52080.1 - 1.6 8.9 11.7 4.8 7.3 3.1 3.0 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.3 EGO52080.1 - 2.3 8.1 17.3 2 8.2 3.4 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2203 PF09969.4 EGO52080.1 - 2.6 8.2 10.2 0.61 10.3 1.2 2.8 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Mto2_bdg PF12808.2 EGO52080.1 - 3.6 7.7 11.3 7.3 6.7 2.5 2.8 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_2 PF07716.10 EGO52080.1 - 3.7 7.4 19.6 0.27 11.0 0.7 4.1 3 1 2 5 5 5 0 Basic region leucine zipper Occludin_ELL PF07303.8 EGO52080.1 - 7.5 7.3 12.1 2.3 8.9 5.7 2.1 2 0 0 2 2 2 0 Occludin homology domain Glyco_hydro_43 PF04616.9 EGO52081.1 - 8.5e-19 67.7 0.0 1.2e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 HD PF01966.17 EGO52082.1 - 0.012 15.6 0.0 0.03 14.3 0.0 1.7 1 1 0 1 1 1 0 HD domain SnoaL PF07366.7 EGO52086.1 - 3.7e-15 55.6 0.5 2.6e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EGO52086.1 - 7.3e-06 26.3 0.4 4.4e-05 23.8 0.0 2.5 3 0 0 3 3 3 1 SnoaL-like domain MFS_1 PF07690.11 EGO52087.1 - 1.3e-43 149.0 48.0 9.9e-43 146.1 31.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO52087.1 - 5.1e-20 71.2 11.7 7.3e-20 70.6 8.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGO52087.1 - 1.8e-15 56.4 38.3 3.7e-15 55.4 9.2 3.4 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 EGO52087.1 - 0.14 12.0 2.8 1.6 8.5 0.1 2.8 2 1 0 2 2 2 0 MFS_1 like family Zip PF02535.17 EGO52089.1 - 1.8e-48 165.2 3.5 2.9e-48 164.5 2.4 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter UPF0261 PF06792.6 EGO52092.1 - 3.3e-157 523.1 0.0 3.8e-157 522.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) CSTF2_hinge PF14327.1 EGO52092.1 - 0.14 12.3 0.2 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 TIM-br_sig_trns PF09370.5 EGO52093.1 - 1e-136 454.2 0.4 1.2e-136 454.1 0.3 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 EGO52093.1 - 1.4e-05 24.4 0.1 2.2e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Cupin_1 PF00190.17 EGO52094.1 - 2.6e-34 117.7 0.0 1.4e-17 63.4 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EGO52094.1 - 1e-27 95.3 0.8 2.4e-13 49.3 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EGO52094.1 - 3e-10 39.3 0.0 0.0001 21.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EGO52094.1 - 2.2e-07 30.6 0.1 0.00068 19.3 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain ARD PF03079.9 EGO52094.1 - 0.00087 19.2 0.4 0.09 12.7 0.0 2.3 2 0 0 2 2 2 1 ARD/ARD' family MannoseP_isomer PF01050.13 EGO52094.1 - 0.00092 18.8 0.0 0.079 12.5 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase GPI PF06560.6 EGO52094.1 - 0.0083 15.1 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) FdtA PF05523.6 EGO52094.1 - 0.014 14.9 0.0 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 WxcM-like, C-terminal 2OG-FeII_Oxy_5 PF13759.1 EGO52094.1 - 0.034 14.4 0.0 24 5.2 0.0 3.3 2 1 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase cNMP_binding PF00027.24 EGO52094.1 - 0.036 13.8 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain 3-HAO PF06052.7 EGO52094.1 - 0.067 12.5 0.0 0.73 9.2 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_7 PF12973.2 EGO52094.1 - 0.1 12.4 0.5 0.59 10.0 0.1 2.4 3 1 0 4 4 4 0 ChrR Cupin-like domain DUF1110 PF06533.7 EGO52095.1 - 0.017 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) DUF4403 PF14356.1 EGO52095.1 - 0.058 11.6 0.3 0.066 11.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) Dicty_REP PF05086.7 EGO52095.1 - 0.12 10.1 2.1 0.11 10.1 1.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 EGO52095.1 - 0.63 7.9 8.9 1 7.2 6.2 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 EGO52095.1 - 1.7 8.4 11.7 0.19 11.4 5.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF1275 PF06912.6 EGO52096.1 - 1.3e-40 138.8 14.3 1.6e-40 138.5 9.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Hemerythrin PF01814.18 EGO52097.1 - 1e-14 54.8 0.1 1.4e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Acetyltransf_7 PF13508.1 EGO52098.1 - 0.00021 21.3 0.0 0.00039 20.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO52098.1 - 0.0012 18.9 0.0 0.0057 16.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO52098.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Phage_T4_Ndd PF06591.6 EGO52099.1 - 0.15 11.6 0.0 0.36 10.3 0.0 1.6 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) SET PF00856.23 EGO52100.1 - 6.6e-14 52.5 0.0 2.2e-12 47.6 0.0 2.9 2 1 0 2 2 2 1 SET domain TPR_11 PF13414.1 EGO52100.1 - 2.4e-10 39.9 9.6 3.4e-06 26.5 0.0 4.1 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 EGO52100.1 - 3.1e-08 32.9 16.7 0.00046 19.8 1.7 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGO52100.1 - 7e-06 25.4 8.8 0.067 12.8 1.9 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO52100.1 - 2.2e-05 24.2 6.5 0.0063 16.4 1.3 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGO52100.1 - 0.0012 18.4 11.1 0.33 10.8 1.7 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGO52100.1 - 1.9 9.3 7.2 4 8.3 0.4 4.5 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGO52100.1 - 2.1 9.0 12.9 9.1 7.0 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Tim54 PF11711.3 EGO52101.1 - 0.0027 16.3 0.5 0.004 15.8 0.4 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.11 EGO52101.1 - 0.072 12.9 2.8 0.11 12.4 1.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF605 PF04652.11 EGO52101.1 - 0.37 10.1 12.8 0.5 9.6 8.9 1.1 1 0 0 1 1 1 0 Vta1 like Pox_Ag35 PF03286.9 EGO52101.1 - 8.9 5.7 14.1 15 5.0 9.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SUR7 PF06687.7 EGO52102.1 - 3.4e-33 114.9 0.5 4e-33 114.7 0.4 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EGO52102.1 - 3.5e-07 30.2 7.5 3.5e-07 30.2 5.2 1.6 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Mem_trans PF03547.13 EGO52102.1 - 0.028 12.7 0.1 0.028 12.7 0.1 1.4 2 0 0 2 2 2 0 Membrane transport protein Trp_oprn_chp PF09534.5 EGO52102.1 - 0.029 13.9 0.1 0.029 13.9 0.1 1.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3357 PF11837.3 EGO52102.1 - 0.049 13.4 4.6 1.3 8.9 0.8 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF3357) DUF1180 PF06679.7 EGO52102.1 - 0.21 11.4 0.9 22 4.8 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1180) DUF2417 PF10329.4 EGO52102.1 - 3.1 7.1 5.6 16 4.7 3.9 2.1 1 1 0 1 1 1 0 Region of unknown function (DUF2417) Fructosamin_kin PF03881.9 EGO52103.1 - 1e-30 106.6 0.0 1.3e-30 106.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EGO52103.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.11 EGO52104.1 - 1.4e-46 158.8 24.0 8e-43 146.4 9.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO52104.1 - 1.3e-09 37.1 9.0 1.3e-09 37.1 6.2 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter Ferric_reduct PF01794.14 EGO52105.1 - 1.4e-14 54.2 12.2 1.4e-14 54.2 8.4 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EGO52105.1 - 1.7e-08 34.2 0.1 8.3e-08 32.0 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EGO52105.1 - 5e-05 23.2 0.0 0.022 14.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EGO52105.1 - 0.082 13.4 0.0 0.16 12.5 0.0 1.6 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Senescence PF06911.7 EGO52106.1 - 0.004 16.8 8.4 0.0062 16.2 5.8 1.3 1 1 0 1 1 1 1 Senescence-associated protein CsbD PF05532.7 EGO52106.1 - 0.019 14.6 0.3 0.019 14.6 0.2 2.1 2 1 0 2 2 2 0 CsbD-like SseC PF04888.7 EGO52106.1 - 0.14 11.5 8.5 0.17 11.2 5.9 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family WD40 PF00400.27 EGO52108.1 - 1.2e-25 88.3 5.6 4.7e-12 45.3 0.0 5.0 6 0 0 6 6 6 4 WD domain, G-beta repeat PUL PF08324.6 EGO52109.1 - 3.1e-79 265.5 0.0 4.1e-79 265.1 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 EGO52109.1 - 2.7e-45 153.1 0.2 5e-45 152.2 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EGO52109.1 - 4.7e-39 130.8 13.0 1.1e-07 31.5 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat SRR1 PF07985.7 EGO52112.1 - 0.034 14.0 0.0 0.096 12.6 0.0 1.8 1 0 0 1 1 1 0 SRR1 PAN_4 PF14295.1 EGO52113.1 - 1.9e-09 37.0 4.3 3.6e-09 36.1 3.0 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EGO52113.1 - 0.079 12.7 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 PAN domain Epimerase PF01370.16 EGO52114.1 - 7.5e-08 32.0 0.0 1.2e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO52114.1 - 1.7e-06 28.1 0.0 3.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EGO52114.1 - 1.6e-05 25.1 0.0 3.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EGO52114.1 - 0.016 13.9 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGO52114.1 - 0.025 13.5 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein HSA PF07529.8 EGO52114.1 - 0.096 12.4 0.1 0.61 9.9 0.0 2.1 2 0 0 2 2 2 0 HSA DUF1456 PF07308.8 EGO52114.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) DXP_reductoisom PF02670.11 EGO52114.1 - 0.13 12.8 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2-Hacid_dh_C PF02826.14 EGO52118.1 - 3.2e-47 159.9 0.2 2.6e-46 156.9 0.2 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGO52118.1 - 2.2e-07 30.4 0.0 3.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGO52118.1 - 0.02 14.7 0.3 0.04 13.7 0.2 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EGO52118.1 - 0.044 13.1 0.5 0.23 10.8 0.3 2.0 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain adh_short PF00106.20 EGO52119.1 - 2.6e-24 85.9 0.1 3.6e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO52119.1 - 7.8e-13 48.4 0.1 1.5e-12 47.5 0.1 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGO52119.1 - 1.7e-07 31.2 0.0 2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGO52119.1 - 0.027 13.9 0.0 0.045 13.1 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO52119.1 - 0.098 11.3 0.1 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ras PF00071.17 EGO52120.1 - 1.8e-40 138.0 0.0 4.9e-40 136.5 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGO52120.1 - 9.1e-15 55.1 0.0 1.3e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO52120.1 - 8.9e-11 41.3 0.0 3.3e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO52120.1 - 0.001 18.2 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 EGO52120.1 - 0.0032 17.3 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EGO52120.1 - 0.0048 16.8 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EGO52120.1 - 0.014 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EGO52120.1 - 0.014 15.4 0.0 0.03 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EGO52120.1 - 0.015 14.7 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EGO52120.1 - 0.021 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.7 EGO52120.1 - 0.03 13.9 0.0 0.081 12.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 EGO52120.1 - 0.03 14.0 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EGO52120.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EGO52120.1 - 0.07 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 EGO52120.1 - 0.072 12.2 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 G-alpha PF00503.15 EGO52120.1 - 0.17 10.5 0.1 0.36 9.4 0.0 1.5 2 0 0 2 2 2 0 G-protein alpha subunit Glyco_hydro_2 PF00703.16 EGO52121.1 - 8.3e-11 42.3 0.8 1.9e-10 41.1 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EGO52121.1 - 8.8e-09 35.1 0.1 3.5e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EGO52121.1 - 0.00023 20.2 0.1 0.0004 19.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Qn_am_d_aIII PF09099.5 EGO52121.1 - 0.027 14.8 0.1 5.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III DUF402 PF04167.8 EGO52121.1 - 0.044 13.6 2.5 0.19 11.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF402) ADH_N PF08240.7 EGO52122.1 - 1.6e-30 105.0 1.2 3.6e-30 103.9 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO52122.1 - 1.8e-25 88.9 0.2 4.6e-25 87.6 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO52122.1 - 4.1e-06 27.6 0.1 1e-05 26.4 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EGO52122.1 - 0.00056 20.4 0.0 0.0011 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.16 EGO52122.1 - 0.00082 18.9 0.7 0.0013 18.3 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Met_10 PF02475.11 EGO52122.1 - 0.0025 17.4 0.3 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 Met-10+ like-protein HI0933_like PF03486.9 EGO52122.1 - 0.0057 15.1 0.5 0.017 13.6 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 EGO52122.1 - 0.0086 15.4 0.4 0.05 12.9 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 EGO52122.1 - 0.023 13.8 0.0 0.043 12.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EGO52122.1 - 0.083 12.7 0.4 0.19 11.5 0.3 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Mur_ligase_M PF08245.7 EGO52123.1 - 0.0072 16.3 0.1 0.057 13.4 0.0 2.5 1 1 0 1 1 1 1 Mur ligase middle domain Mitofilin PF09731.4 EGO52124.1 - 8.6e-165 549.7 4.3 1.2e-164 549.1 3.0 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Ras PF00071.17 EGO52124.1 - 4.7e-58 195.1 0.6 9.3e-58 194.1 0.4 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO52124.1 - 3.2e-18 66.3 0.0 8.4e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO52124.1 - 5.6e-14 51.7 0.1 5.6e-14 51.7 0.1 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO52124.1 - 1.6e-07 30.7 0.0 2.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGO52124.1 - 4.7e-07 29.4 0.1 9.4e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGO52124.1 - 0.00013 21.8 0.0 0.00038 20.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Fib_alpha PF08702.5 EGO52124.1 - 0.84 9.7 6.2 0.58 10.2 1.4 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Prominin PF05478.6 EGO52124.1 - 1.4 6.3 6.4 2.7 5.4 4.4 1.4 1 0 0 1 1 1 0 Prominin H-kinase_dim PF02895.9 EGO52124.1 - 7.6 6.9 8.2 85 3.5 5.7 2.8 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Syja_N PF02383.13 EGO52125.1 - 1.1e-91 306.8 0.0 1.5e-91 306.4 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain DUF1249 PF06853.7 EGO52125.1 - 0.016 14.8 0.5 0.35 10.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1249) Tropomyosin_1 PF12718.2 EGO52126.1 - 0.00049 19.9 1.3 0.0016 18.3 0.9 1.8 1 0 0 1 1 1 1 Tropomyosin like CALCOCO1 PF07888.6 EGO52126.1 - 0.0025 16.2 0.8 0.0041 15.4 0.6 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.6 EGO52126.1 - 0.0051 16.6 0.9 0.0051 16.6 0.6 2.2 3 1 0 3 3 3 1 Autophagy protein 16 (ATG16) IncA PF04156.9 EGO52126.1 - 0.0055 16.3 4.4 0.0055 16.3 3.1 1.9 2 0 0 2 2 2 1 IncA protein SlyX PF04102.7 EGO52126.1 - 0.0062 16.8 3.3 1.2 9.5 0.1 3.1 2 1 1 3 3 2 2 SlyX PG_binding_1 PF01471.13 EGO52126.1 - 0.0079 16.1 0.0 5.6 7.0 0.0 3.0 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Laminin_II PF06009.7 EGO52126.1 - 0.02 14.6 0.9 0.044 13.5 0.6 1.6 1 0 0 1 1 1 0 Laminin Domain II NPV_P10 PF05531.7 EGO52126.1 - 0.028 14.6 0.4 1.3 9.3 0.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 EGO52126.1 - 0.066 11.6 0.6 0.12 10.8 0.4 1.3 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 EGO52126.1 - 0.13 10.8 3.6 0.39 9.3 2.6 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 EGO52126.1 - 0.34 9.9 1.1 0.64 9.0 0.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Syntaxin-6_N PF09177.6 EGO52126.1 - 0.74 10.2 3.3 0.97 9.8 0.4 2.5 2 1 1 3 3 2 0 Syntaxin 6, N-terminal CLTH PF10607.4 EGO52127.1 - 3.9e-28 97.9 0.0 8.2e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EGO52127.1 - 1.5e-17 62.9 1.3 3.3e-17 61.9 0.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EGO52127.1 - 7e-05 22.1 0.0 0.00013 21.2 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EGO52127.1 - 0.00011 21.8 0.4 0.00019 21.2 0.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO52127.1 - 0.00029 20.7 0.8 0.00048 20.0 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO52127.1 - 0.0022 17.6 0.2 0.0035 17.0 0.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGO52127.1 - 0.0048 16.5 0.2 0.0075 15.9 0.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO52127.1 - 0.0082 15.7 0.8 0.015 14.9 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sigma70_ner PF04546.8 EGO52127.1 - 0.027 14.0 5.9 0.063 12.8 4.1 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-rbx1 PF12678.2 EGO52127.1 - 0.039 14.0 0.2 0.071 13.2 0.2 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger Senescence_reg PF04520.8 EGO52127.1 - 0.058 13.8 0.3 0.13 12.7 0.2 1.6 1 0 0 1 1 1 0 Senescence regulator zf-C3HC4_4 PF15227.1 EGO52127.1 - 0.16 11.8 1.0 0.31 10.9 0.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EGO52127.1 - 0.17 11.3 3.0 0.22 11.0 1.2 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Nop14 PF04147.7 EGO52127.1 - 0.19 9.5 8.0 0.25 9.2 5.6 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EGO52127.1 - 0.33 10.1 8.4 0.52 9.5 5.8 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.7 EGO52127.1 - 0.44 10.2 9.1 0.7 9.5 6.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.5 EGO52127.1 - 0.77 10.0 14.0 1.7 8.9 9.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 EGO52127.1 - 1.3 8.8 6.0 2.7 7.7 4.2 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal TFIIA PF03153.8 EGO52127.1 - 1.8 8.3 10.6 2.6 7.8 7.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleoplasmin PF03066.10 EGO52127.1 - 5.2 6.5 17.1 8.6 5.8 11.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin PgaD PF13994.1 EGO52128.1 - 8.9 5.7 10.3 0.3 10.5 1.7 2.4 2 1 0 2 2 2 0 PgaD-like protein PPP4R2 PF09184.6 EGO52129.1 - 1.5e-08 34.5 0.0 1.5e-08 34.5 0.0 3.3 3 1 1 4 4 4 1 PPP4R2 GATA PF00320.22 EGO52130.1 - 5.3e-16 57.6 4.9 1.1e-15 56.6 3.4 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 EGO52130.1 - 9.2e-13 48.1 0.0 1.9e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EGO52130.1 - 1.2e-08 35.2 0.0 4.4e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.1 EGO52130.1 - 8.9e-07 28.8 0.0 1.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EGO52130.1 - 3.3e-05 23.6 0.2 0.00011 21.9 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EGO52130.1 - 0.00068 19.6 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold TF_Zn_Ribbon PF08271.7 EGO52130.1 - 0.19 11.1 0.6 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.1 EGO52130.1 - 2.3 8.0 4.7 0.66 9.7 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) FAD-oxidase_C PF02913.14 EGO52131.1 - 5.7e-59 199.4 0.0 8.2e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGO52131.1 - 1.9e-37 127.8 0.3 9.1e-37 125.6 0.0 2.2 2 1 1 3 3 3 1 FAD binding domain Amidase PF01425.16 EGO52132.1 - 2.5e-67 227.6 0.1 3.3e-67 227.2 0.1 1.1 1 0 0 1 1 1 1 Amidase DUF1388 PF07142.7 EGO52134.1 - 0.24 11.1 1.7 0.44 10.3 1.2 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) Glyco_tranf_2_3 PF13641.1 EGO52136.1 - 2.2e-19 70.1 0.0 3.1e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGO52136.1 - 2.5e-07 30.1 0.0 6e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EGO52136.1 - 0.0002 21.0 0.0 0.0015 18.2 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_64 PF09258.5 EGO52136.1 - 0.00027 20.1 0.2 0.0005 19.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain GWT1 PF06423.7 EGO52138.1 - 5.3e-42 143.1 4.2 1.5e-41 141.6 2.9 1.8 1 0 0 1 1 1 1 GWT1 Pkinase PF00069.20 EGO52139.1 - 5.4e-64 215.8 0.0 1.5e-63 214.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO52139.1 - 3.3e-36 124.6 0.0 5.4e-31 107.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGO52139.1 - 9.7e-06 24.7 0.1 0.012 14.5 0.0 2.3 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EGO52139.1 - 0.014 15.1 12.2 0.46 10.1 7.8 3.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EGO52139.1 - 0.018 14.4 0.1 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family tRNA-synt_2 PF00152.15 EGO52140.1 - 2.4e-72 243.5 0.0 3.2e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGO52140.1 - 3.7e-08 33.0 0.2 4.5e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain eIF3_subunit PF08597.5 EGO52140.1 - 1.4 8.3 9.6 2.8 7.4 6.6 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Na_Ca_ex PF01699.19 EGO52141.1 - 3.7e-37 127.0 25.0 2.5e-23 82.2 8.5 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein BLVR PF06375.6 EGO52141.1 - 0.0085 15.9 2.5 0.022 14.5 1.7 1.6 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) Neur_chan_memb PF02932.11 EGO52141.1 - 9.6 6.0 8.2 23 4.7 0.3 2.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Clr5 PF14420.1 EGO52142.1 - 1.6e-20 72.6 1.8 1.6e-20 72.6 1.2 2.2 2 0 0 2 2 2 1 Clr5 domain Nop14 PF04147.7 EGO52142.1 - 0.0013 16.7 12.3 0.0013 16.7 8.6 2.6 2 1 0 2 2 2 1 Nop14-like family DEAD PF00270.24 EGO52144.1 - 2.1e-24 85.8 0.1 3.3e-22 78.7 0.0 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO52144.1 - 3e-23 81.4 0.7 9.5e-23 79.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TRAP_alpha PF03896.11 EGO52144.1 - 2 7.3 11.5 1.9 7.4 0.3 2.9 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit DUF4448 PF14610.1 EGO52144.1 - 7.5 5.9 6.5 9.3 5.6 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) tRNA-synt_1 PF00133.17 EGO52145.1 - 6.9e-156 519.7 0.0 9.5e-156 519.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EGO52145.1 - 4.8e-22 78.1 0.0 1.1e-12 47.4 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EGO52145.1 - 1.9e-19 69.9 0.2 7.8e-19 67.9 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 EGO52145.1 - 0.0078 15.8 3.3 0.0078 15.8 2.3 2.2 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 EGO52145.1 - 0.028 13.5 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain YndJ PF14158.1 EGO52149.1 - 0.19 10.7 0.5 0.26 10.3 0.4 1.2 1 0 0 1 1 1 0 YndJ-like protein DUF2228 PF10228.4 EGO52151.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Tom37_C PF11801.3 EGO52152.1 - 3e-20 72.7 0.0 5.8e-20 71.8 0.0 1.5 1 1 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 EGO52152.1 - 7.2e-18 64.6 0.7 1.8e-17 63.3 0.1 1.9 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein PIG-U PF06728.8 EGO52153.1 - 1e-125 419.5 28.4 1.2e-125 419.3 19.7 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.8 EGO52153.1 - 0.00011 21.9 1.0 0.00011 21.9 0.7 2.0 1 1 1 2 2 2 1 Mannosyltransferase (PIG-M) Pescadillo_N PF06732.6 EGO52154.1 - 2.7e-112 374.6 0.1 2.7e-112 374.6 0.0 2.6 2 1 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EGO52154.1 - 9e-10 38.5 0.0 3.8e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RRN9 PF10680.4 EGO52155.1 - 1.4e-19 69.5 2.9 1.4e-19 69.5 2.0 2.2 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor Kinesin PF00225.18 EGO52156.1 - 1.9e-111 372.0 0.2 5e-111 370.6 0.1 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 EGO52156.1 - 2.1e-06 27.9 2.8 2.1e-06 27.9 1.9 5.1 4 1 1 5 5 5 1 Kinesin-associated microtubule-binding UPF0183 PF03676.9 EGO52157.1 - 5.7e-33 114.0 0.1 2.9e-19 68.9 0.0 5.5 4 1 0 4 4 4 4 Uncharacterised protein family (UPF0183) DUF883 PF05957.8 EGO52158.1 - 1.6 9.1 6.1 37 4.8 1.1 3.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) zf-Tim10_DDP PF02953.10 EGO52159.1 - 1.7e-20 72.0 2.2 1.9e-20 71.8 1.6 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EGO52159.1 - 0.052 13.0 1.9 0.071 12.5 1.3 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) tRNA-synt_2 PF00152.15 EGO52160.1 - 1.9e-78 263.5 0.0 2.4e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGO52160.1 - 3e-12 46.2 0.0 5.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGO52160.1 - 8.2e-06 25.1 0.0 0.012 14.8 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EGO52160.1 - 0.0094 15.5 0.0 0.7 9.4 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti-like PF12869.2 EGO52160.1 - 0.042 13.3 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 tRNA_anti-like PH_6 PF15406.1 EGO52163.1 - 1.6e-47 160.1 5.8 1.6e-47 160.1 4.1 2.9 3 1 2 5 5 5 1 Pleckstrin homology domain PH PF00169.24 EGO52163.1 - 0.016 15.3 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 PH domain PH_4 PF15404.1 EGO52163.1 - 0.12 11.8 0.4 0.42 10.1 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Aldedh PF00171.17 EGO52164.1 - 1.1e-167 558.1 0.0 1.2e-167 557.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HATPase_c PF02518.21 EGO52168.1 - 7.4e-23 80.3 0.0 1.4e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGO52168.1 - 7.2e-18 64.6 0.3 8.5e-15 54.7 0.2 2.5 1 1 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EGO52168.1 - 4.2e-10 39.9 0.0 1.2e-08 35.2 0.0 2.8 3 0 0 3 3 3 1 PAS domain PAS PF00989.19 EGO52168.1 - 1.9e-07 30.8 0.2 2e-06 27.5 0.0 2.8 3 0 0 3 3 3 1 PAS fold HisKA PF00512.20 EGO52168.1 - 2.8e-07 30.4 0.1 6.8e-07 29.1 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 EGO52168.1 - 2.5e-05 24.2 0.0 0.0033 17.4 0.0 3.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 EGO52168.1 - 0.0019 17.9 0.0 0.08 12.8 0.0 2.9 2 0 0 2 2 2 1 PAS domain GAF_2 PF13185.1 EGO52168.1 - 0.0022 18.4 0.0 0.24 11.8 0.0 3.2 3 0 0 3 3 3 1 GAF domain GAF_3 PF13492.1 EGO52168.1 - 0.022 14.8 0.0 0.08 13.0 0.0 2.0 2 0 0 2 2 2 0 GAF domain Rad1 PF02144.11 EGO52172.1 - 1.2e-89 299.7 0.0 1.4e-89 299.5 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Bromodomain PF00439.20 EGO52173.1 - 4e-27 93.9 1.1 7.4e-27 93.0 0.7 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EGO52173.1 - 2.3e-09 37.2 0.6 4.3e-09 36.4 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO52173.1 - 5.1e-09 36.0 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGO52173.1 - 0.098 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Fn_bind PF02986.9 EGO52173.1 - 0.16 11.4 0.4 0.33 10.5 0.3 1.5 1 0 0 1 1 1 0 Fibronectin binding repeat Trehalase PF01204.13 EGO52175.1 - 5e-120 401.5 0.5 3.6e-119 398.7 0.4 1.9 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.9 EGO52175.1 - 1.1e-05 24.3 0.7 0.00018 20.3 0.0 2.1 2 0 0 2 2 2 2 Amylo-alpha-1,6-glucosidase Beta_elim_lyase PF01212.16 EGO52176.1 - 3.5e-68 229.8 0.0 4.2e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EGO52176.1 - 2.3e-05 22.8 0.0 3.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGO52176.1 - 0.0049 15.9 0.1 0.025 13.6 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.13 EGO52178.1 - 5.9e-14 51.5 0.4 1.3e-13 50.4 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dus PF01207.12 EGO52184.1 - 7.7e-43 146.4 0.2 1.8e-42 145.3 0.1 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) SR-25 PF10500.4 EGO52184.1 - 0.091 12.2 5.7 0.14 11.6 3.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pyrophosphatase PF00719.14 EGO52185.1 - 2.8e-51 173.0 0.2 3.5e-51 172.7 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.4 EGO52186.1 - 4.2e-23 81.0 0.3 6.5e-23 80.4 0.2 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.8 EGO52187.1 - 1.6e-16 59.7 0.4 1.6e-16 59.7 0.3 2.0 3 0 0 3 3 3 1 Sec20 CompInhib_SCIN PF11546.3 EGO52187.1 - 0.13 12.0 0.3 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 Staphylococcal complement inhibitor SCIN Syntaxin-6_N PF09177.6 EGO52187.1 - 7.9 6.9 8.0 4.3 7.7 0.5 3.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Abhydrolase_6 PF12697.2 EGO52188.1 - 2.2e-20 73.5 1.0 3.5e-20 72.8 0.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO52188.1 - 2.8e-09 36.8 0.0 5.8e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO52188.1 - 0.001 18.6 0.2 0.049 13.1 0.1 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EGO52188.1 - 0.019 15.2 0.0 4.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.20 EGO52188.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Pyr_redox_3 PF13738.1 EGO52189.1 - 1.7e-22 80.5 0.0 1.4e-21 77.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO52189.1 - 1.1e-08 34.9 0.0 3.3e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EGO52189.1 - 1.4e-07 30.0 0.1 1.9e-06 26.3 0.0 2.5 2 2 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EGO52189.1 - 1.1e-05 24.5 0.0 0.0067 15.3 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGO52189.1 - 0.00017 21.3 0.1 0.039 13.7 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGO52189.1 - 0.00028 20.8 0.0 0.28 11.0 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGO52189.1 - 0.26 10.0 0.0 0.46 9.2 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A GPI-anchored PF10342.4 EGO52192.1 - 1.8e-15 57.2 0.8 1.8e-15 57.2 0.6 2.7 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2141 PF09912.4 EGO52192.1 - 0.037 13.6 0.1 0.14 11.7 0.0 2.0 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2141) Herpes_TAF50 PF03326.8 EGO52192.1 - 0.45 9.3 12.7 0.58 9.0 8.8 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Rifin_STEVOR PF02009.11 EGO52192.1 - 0.58 9.7 4.8 0.77 9.3 3.3 1.3 1 0 0 1 1 1 0 Rifin/stevor family DNA_pol_viral_N PF00242.12 EGO52192.1 - 8 5.3 10.9 10 5.0 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SpoIIE PF07228.7 EGO52193.1 - 2.8e-12 46.7 0.9 9.5e-11 41.7 0.6 2.3 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EGO52193.1 - 1.2e-09 37.9 0.1 0.00045 19.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EGO52193.1 - 2.9e-07 30.1 0.1 5.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Fer2_3 PF13085.1 EGO52194.1 - 8.3e-33 112.5 0.0 1.3e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.1 EGO52194.1 - 2.8e-09 36.8 4.4 2.8e-09 36.8 3.1 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 EGO52194.1 - 2.9e-09 37.1 6.1 2.9e-09 37.1 4.2 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EGO52194.1 - 8.2e-05 22.9 1.7 8.2e-05 22.9 1.2 2.6 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EGO52194.1 - 0.00012 21.7 3.6 0.00012 21.7 2.5 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGO52194.1 - 0.0003 20.9 4.5 0.035 14.3 0.6 3.0 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer2 PF00111.22 EGO52194.1 - 0.0026 17.4 0.3 0.0026 17.4 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DNA_pol3_tau_4 PF12168.3 EGO52194.1 - 0.05 13.9 2.1 0.11 12.9 0.2 2.1 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_7 PF12838.2 EGO52194.1 - 1.5 9.2 14.3 0.044 14.1 4.5 2.4 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 EGO52194.1 - 1.8 9.2 5.9 0.98 10.0 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Med12 PF09497.5 EGO52196.1 - 3.9e-28 97.2 2.2 2.6e-27 94.5 0.3 3.0 3 0 0 3 3 3 1 Transcription mediator complex subunit Med12 OmpH PF03938.9 EGO52196.1 - 0.97 9.3 29.7 0.066 13.1 3.5 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) THF_DHG_CYH PF00763.18 EGO52197.1 - 2e-19 69.7 0.1 2.8e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EGO52197.1 - 7.8e-13 47.8 0.0 6.7e-08 31.7 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MMS19_N PF14500.1 EGO52199.1 - 4.6e-49 167.0 0.2 4.4e-48 163.8 0.0 2.6 2 1 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EGO52199.1 - 3e-16 59.1 0.3 2.4e-12 46.3 0.0 3.4 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal DUF2013 PF09431.5 EGO52199.1 - 0.15 11.8 1.3 3.2 7.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2013) DUF106 PF01956.11 EGO52200.1 - 3.3e-57 192.6 2.0 4.2e-57 192.3 1.4 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 RNA_pol_Rbc25 PF08292.7 EGO52201.1 - 7.1e-11 42.3 0.1 1.6e-10 41.2 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase III subunit Rpc25 S1_2 PF13509.1 EGO52201.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 S1 domain S1 PF00575.18 EGO52201.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 S1 RNA binding domain NUFIP1 PF10453.4 EGO52202.1 - 7e-12 44.6 3.2 2.7e-11 42.7 2.2 2.1 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EGO52202.1 - 0.018 14.6 5.7 0.036 13.7 4.0 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2785 PF10978.3 EGO52202.1 - 1.7 8.1 3.2 1.5 8.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2785) AAA_23 PF13476.1 EGO52202.1 - 8.2 6.6 10.7 0.54 10.5 3.8 1.6 2 0 0 2 2 2 0 AAA domain DUF624 PF04854.9 EGO52204.1 - 0.032 14.0 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF624 SET PF00856.23 EGO52205.1 - 1.1e-12 48.5 0.0 8.4e-11 42.4 0.0 2.5 1 1 0 1 1 1 1 SET domain Ribosomal_S19 PF00203.16 EGO52206.1 - 7.8e-34 115.1 0.3 1.2e-33 114.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 gag-asp_proteas PF13975.1 EGO52206.1 - 0.11 12.3 0.0 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Glyco_hydro_53 PF07745.8 EGO52207.1 - 1e-112 376.2 0.4 1.2e-112 376.0 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 ADH_zinc_N PF00107.21 EGO52208.1 - 2.2e-07 30.5 0.0 3.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO52208.1 - 0.00097 18.8 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain BtpA PF03437.10 EGO52208.1 - 0.0082 15.4 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 BtpA family Glutaredoxin PF00462.19 EGO52209.1 - 1.1e-13 50.8 0.0 4.6e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin tRNA-synt_1f PF01921.13 EGO52209.1 - 0.019 13.6 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) F-box PF00646.28 EGO52210.1 - 0.0026 17.3 0.0 0.0073 15.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain VESA1_N PF12785.2 EGO52211.1 - 2.7 6.8 11.7 4.4 6.1 8.1 1.3 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Ribosomal_L21p PF00829.16 EGO52212.1 - 1.2e-05 25.2 0.0 1.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.20 EGO52213.1 - 9.1e-45 152.8 0.0 1.9e-44 151.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO52213.1 - 3.1e-19 69.0 0.1 2.2e-18 66.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO52213.1 - 8.6e-06 24.9 0.1 0.01 14.8 0.0 3.1 2 1 0 2 2 2 2 Kinase-like PsaA_PsaB PF00223.14 EGO52213.1 - 0.057 11.5 0.0 0.082 10.9 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein RIO1 PF01163.17 EGO52213.1 - 0.07 12.4 0.5 0.16 11.3 0.0 1.9 3 0 0 3 3 3 0 RIO1 family Kdo PF06293.9 EGO52213.1 - 0.081 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_60s PF00428.14 EGO52214.1 - 1.4e-27 95.9 14.2 1.5e-27 95.7 9.8 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein SPT2 PF08243.6 EGO52215.1 - 2.2e-06 27.9 25.9 2.2e-06 27.9 18.0 2.6 2 1 0 2 2 2 1 SPT2 chromatin protein Ribosomal_S8e PF01201.17 EGO52216.1 - 1.5e-33 115.7 5.7 2.8e-33 114.8 4.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e PAP2_3 PF14378.1 EGO52218.1 - 4.6e-22 78.4 9.5 1.4e-20 73.6 1.0 2.9 3 1 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.16 EGO52218.1 - 0.019 14.6 6.8 0.016 14.8 3.1 2.0 1 1 1 2 2 2 0 PAP2 superfamily VWA_3 PF13768.1 EGO52219.1 - 4.2e-27 94.7 0.0 7.5e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EGO52219.1 - 6.9e-20 70.8 0.0 2.2e-19 69.3 0.0 1.7 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EGO52219.1 - 6.9e-14 52.3 0.0 1.4e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EGO52219.1 - 4.7e-09 35.5 0.0 1.1e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 EGO52219.1 - 4.4e-08 33.0 0.0 7.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_hydro_2_N PF02837.13 EGO52220.1 - 1.8e-21 76.4 0.6 4e-21 75.3 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EGO52220.1 - 1.8e-14 53.3 0.0 3.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EGO52220.1 - 1.1e-09 38.6 0.1 1.6e-08 35.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 SnoaL_2 PF12680.2 EGO52221.1 - 2.9e-05 24.4 0.0 3.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF2358 PF10184.4 EGO52221.1 - 0.00069 19.5 0.0 0.00095 19.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) Ank_2 PF12796.2 EGO52222.1 - 4.5e-17 62.1 0.1 2.8e-09 37.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO52222.1 - 2.4e-10 40.6 0.0 1.6e-06 28.4 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO52222.1 - 1.3e-08 34.8 0.1 7.6e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EGO52222.1 - 4.3e-07 29.4 0.0 4.3e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 EGO52222.1 - 1.1e-05 25.1 0.0 0.0063 16.6 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat p450 PF00067.17 EGO52223.1 - 2.7e-40 138.2 0.0 6.6e-40 136.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EGO52224.1 - 6.8e-116 387.4 19.7 7.9e-116 387.2 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO52224.1 - 1.8e-22 79.5 66.5 8.3e-20 70.7 23.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CBM_5_12 PF02839.9 EGO52226.1 - 0.015 14.8 0.3 0.05 13.2 0.2 1.9 1 0 0 1 1 1 0 Carbohydrate binding domain DUF3446 PF11928.3 EGO52228.1 - 0.61 10.3 14.5 1.1 9.5 2.6 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Beta-lactamase PF00144.19 EGO52229.1 - 1.7e-24 86.4 0.7 3.7e-24 85.3 0.5 1.5 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EGO52229.1 - 0.071 12.3 0.0 0.42 9.8 0.0 2.0 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Asp PF00026.18 EGO52230.1 - 2.9e-73 246.8 4.8 3.6e-73 246.5 3.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO52230.1 - 8.7e-07 29.0 0.0 7.8e-06 25.9 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO52230.1 - 2.2e-06 28.0 1.7 0.00018 21.9 0.5 3.0 2 1 0 2 2 2 1 Aspartyl protease OPT PF03169.10 EGO52231.1 - 4.2e-88 296.3 46.1 4.9e-88 296.1 31.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RseC_MucC PF04246.7 EGO52231.1 - 0.41 10.2 4.4 1.3 8.6 0.1 3.2 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Glyco_tranf_2_3 PF13641.1 EGO52232.1 - 1.6e-18 67.3 0.0 2.2e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGO52232.1 - 1.4e-05 24.8 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EGO52232.1 - 0.0019 17.5 0.0 0.007 15.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 MFS_1 PF07690.11 EGO52233.1 - 1.2e-38 132.7 42.3 2.6e-36 125.0 19.2 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF3844 PF12955.2 EGO52235.1 - 5.6e-36 122.7 2.6 9e-36 122.0 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF PF00008.22 EGO52235.1 - 0.79 9.7 5.7 1.8 8.6 4.0 1.6 1 1 0 1 1 1 0 EGF-like domain NTR2 PF15458.1 EGO52236.1 - 2.4e-72 243.2 13.0 4.4e-72 242.3 9.0 1.5 1 0 0 1 1 1 1 Nineteen complex-related protein 2 Hemerythrin PF01814.18 EGO52236.1 - 0.17 12.0 9.5 0.098 12.8 3.7 2.4 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain LSM PF01423.17 EGO52237.1 - 3.9e-19 67.9 0.5 4.5e-19 67.7 0.3 1.0 1 0 0 1 1 1 1 LSM domain WW PF00397.21 EGO52238.1 - 5.2e-07 29.4 6.8 1.2e-06 28.2 4.7 1.7 1 0 0 1 1 1 1 WW domain DUF2853 PF11015.3 EGO52238.1 - 0.12 12.8 0.4 0.21 12.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) Peptidase_C14 PF00656.17 EGO52239.1 - 4e-69 233.0 0.0 5.8e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain RGS PF00615.14 EGO52240.1 - 0.00028 20.9 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Acyl-CoA_dh_1 PF00441.19 EGO52242.1 - 1.3e-31 109.7 2.3 1.3e-31 109.7 1.6 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGO52242.1 - 2.3e-16 60.3 1.5 5.6e-16 59.1 1.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGO52242.1 - 1.8e-15 56.1 0.0 4.1e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGO52242.1 - 5.1e-15 55.9 5.2 8e-15 55.2 1.4 2.5 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain MaoC_dehydrat_N PF13452.1 EGO52243.1 - 0.00047 19.9 0.1 0.043 13.6 0.0 2.7 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase TPT PF03151.11 EGO52244.1 - 8.3e-28 96.9 8.1 8.3e-28 96.9 5.6 1.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EGO52244.1 - 7.3e-09 34.9 18.0 6.7e-08 31.8 12.5 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGO52244.1 - 0.00011 22.1 4.6 0.00011 22.1 3.2 3.0 2 1 0 3 3 3 2 EamA-like transporter family Glyco_hydro_17 PF00332.13 EGO52247.1 - 3.7e-10 39.3 0.4 6.9e-08 31.8 0.1 2.5 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Amidoligase_2 PF12224.3 EGO52249.1 - 4.6e-12 46.0 0.3 3.5e-08 33.3 0.1 2.2 2 0 0 2 2 2 2 Putative amidoligase enzyme Abhydrolase_6 PF12697.2 EGO52251.1 - 2.9e-17 63.3 0.2 4.4e-17 62.7 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO52251.1 - 6e-09 35.8 0.0 1.5e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO52251.1 - 0.0074 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EGO52251.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Glyco_hydro_67M PF07488.7 EGO52252.1 - 5.9e-155 515.0 0.0 7.6e-155 514.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 EGO52252.1 - 2.2e-95 318.3 0.2 3.8e-95 317.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 EGO52252.1 - 1.8e-24 86.0 0.0 3.2e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 EGO52252.1 - 0.00016 22.1 0.0 0.00042 20.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Protoglobin PF11563.3 EGO52253.1 - 1.9e-57 193.3 0.0 2.4e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Protoglobin Toxin_12 PF07740.7 EGO52254.1 - 0.0059 17.0 5.4 0.0083 16.5 3.7 1.3 1 0 0 1 1 1 1 Ion channel inhibitory toxin Atracotoxin PF05353.6 EGO52254.1 - 0.0092 15.7 5.1 0.013 15.3 3.6 1.3 1 0 0 1 1 1 1 Delta Atracotoxin Pkinase PF00069.20 EGO52255.1 - 1.9e-06 27.2 0.0 2.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Glyco_hydro_71 PF03659.9 EGO52256.1 - 1.5e-129 431.8 3.3 2.8e-129 430.9 2.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 SNF2_N PF00176.18 EGO52259.1 - 1.4e-29 102.8 0.0 3.2e-29 101.6 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF2413 PF10310.4 EGO52260.1 - 0.22 10.2 7.9 0.37 9.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) LRR_8 PF13855.1 EGO52260.1 - 0.46 10.2 15.8 0.53 10.0 0.4 3.9 4 0 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 EGO52260.1 - 0.47 10.1 16.0 0.66 9.6 1.5 3.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) HSCB_C PF07743.8 EGO52261.1 - 1.5e-18 66.9 0.8 3.1e-18 66.0 0.6 1.5 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EGO52261.1 - 4.5e-08 32.7 0.0 1.2e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain TFIIA PF03153.8 EGO52261.1 - 0.46 10.3 4.0 0.76 9.6 2.8 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PCI PF01399.22 EGO52263.1 - 1.2e-13 51.2 0.0 9.6e-13 48.3 0.0 2.3 2 0 0 2 2 2 1 PCI domain TPR_19 PF14559.1 EGO52263.1 - 0.0028 17.9 1.4 1.1 9.6 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat RPN7 PF10602.4 EGO52263.1 - 0.0034 16.7 0.2 0.007 15.7 0.1 1.4 1 1 0 1 1 1 1 26S proteasome subunit RPN7 Lipase_GDSL_2 PF13472.1 EGO52264.1 - 8.7e-24 84.6 0.0 1.1e-23 84.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGO52264.1 - 5.5e-10 39.4 0.1 5.4e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FMN_dh PF01070.13 EGO52265.1 - 1.6e-101 339.7 0.0 2.3e-101 339.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EGO52265.1 - 4.4e-18 64.8 0.0 1.5e-17 63.1 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EGO52265.1 - 8.3e-06 24.9 0.2 1.3e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EGO52265.1 - 6.3e-05 22.0 0.1 0.0015 17.4 0.0 2.3 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ATP11 PF06644.6 EGO52265.1 - 0.015 14.7 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 ATP11 protein His_biosynth PF00977.16 EGO52265.1 - 0.082 12.1 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF3712 PF12505.3 EGO52266.1 - 6.8e-30 103.6 2.8 1.6e-29 102.5 1.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EGO52266.1 - 0.0045 17.3 0.4 0.71 10.2 0.1 3.3 3 1 0 3 3 3 1 Late embryogenesis abundant protein SP_C-Propep PF08999.5 EGO52266.1 - 0.033 13.6 0.2 0.054 12.9 0.1 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF2997 PF11211.3 EGO52266.1 - 0.82 9.0 3.2 9.6 5.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) DUF929 PF06053.6 EGO52266.1 - 0.9 8.5 3.8 1.4 7.9 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) HCNGP PF07818.8 EGO52267.1 - 4.6e-19 68.2 0.3 3.1e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 HCNGP-like protein SIS PF01380.17 EGO52268.1 - 4e-57 191.4 0.1 2.2e-30 104.9 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EGO52268.1 - 3.7e-28 98.2 0.0 2.7e-19 69.1 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGO52268.1 - 6.6e-20 71.4 0.0 1.6e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EGO52268.1 - 8.4e-12 44.9 0.0 2.1e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EGO52268.1 - 7.5e-07 28.1 0.0 1.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EGO52268.1 - 0.049 13.3 0.0 0.49 10.0 0.0 2.4 3 0 0 3 3 3 0 SIS domain AAA PF00004.24 EGO52269.1 - 5.1e-43 146.4 0.0 8.7e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGO52269.1 - 7.4e-08 32.5 0.0 5.9e-06 26.3 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EGO52269.1 - 1.6e-06 27.8 0.1 3.7e-05 23.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGO52269.1 - 2.2e-06 27.7 0.0 7.7e-06 25.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGO52269.1 - 2.8e-06 27.4 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EGO52269.1 - 7.4e-06 25.1 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EGO52269.1 - 0.0003 19.7 0.0 0.00066 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EGO52269.1 - 0.00033 20.3 0.0 0.00075 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EGO52269.1 - 0.00051 20.8 0.7 0.0021 18.8 0.2 2.4 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EGO52269.1 - 0.0013 18.6 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO52269.1 - 0.0014 18.9 0.2 0.0078 16.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGO52269.1 - 0.0017 18.2 0.0 0.0063 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EGO52269.1 - 0.0017 17.1 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EGO52269.1 - 0.0026 17.2 0.0 0.0053 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EGO52269.1 - 0.0035 16.5 0.0 0.0065 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EGO52269.1 - 0.0048 16.0 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 EGO52269.1 - 0.005 16.9 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Sigma54_activat PF00158.21 EGO52269.1 - 0.0075 15.7 0.0 0.025 14.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EGO52269.1 - 0.009 15.4 0.1 0.047 13.1 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 EGO52269.1 - 0.0095 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.12 EGO52269.1 - 0.017 14.5 0.0 1.4 8.2 0.0 2.6 3 0 0 3 3 3 0 Thymidylate kinase AAA_24 PF13479.1 EGO52269.1 - 0.019 14.5 0.1 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EGO52269.1 - 0.02 14.4 0.4 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EGO52269.1 - 0.023 14.7 0.0 0.064 13.3 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EGO52269.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGO52269.1 - 0.025 13.8 0.1 0.056 12.6 0.0 1.6 2 0 0 2 2 1 0 PhoH-like protein ResIII PF04851.10 EGO52269.1 - 0.027 14.2 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KaiC PF06745.8 EGO52269.1 - 0.029 13.4 0.3 0.12 11.4 0.0 2.2 3 0 0 3 3 3 0 KaiC Arch_ATPase PF01637.13 EGO52269.1 - 0.032 13.9 0.0 0.14 11.7 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EGO52269.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EGO52269.1 - 0.049 13.2 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EGO52269.1 - 0.053 13.8 4.2 2.6 8.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGO52269.1 - 0.079 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EGO52269.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF4200 PF13863.1 EGO52269.1 - 0.53 10.2 7.4 0.056 13.3 1.9 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) Lactamase_B_2 PF12706.2 EGO52270.1 - 3.7e-23 82.0 0.0 4.5e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGO52270.1 - 7e-10 38.8 0.0 9.5e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain VWA PF00092.23 EGO52271.1 - 2.2e-08 34.0 0.0 4.5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EGO52271.1 - 5.5e-07 29.8 0.1 2.1e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EGO52271.1 - 0.03 14.1 0.2 0.087 12.6 0.0 1.8 2 0 0 2 2 2 0 vWA found in TerF C terminus DUF1387 PF07139.6 EGO52273.1 - 0.16 11.5 2.4 0.21 11.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) RE_TaqI PF09573.5 EGO52275.1 - 0.0041 16.2 1.6 0.63 9.1 0.1 2.1 2 0 0 2 2 2 2 TaqI restriction endonuclease DUF3106 PF11304.3 EGO52275.1 - 0.026 14.9 1.4 2.1 8.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) Zn_clus PF00172.13 EGO52276.1 - 1.9e-09 37.2 13.2 3.2e-09 36.5 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EGO52277.1 - 1.7e-20 73.0 24.6 7.4e-18 64.3 17.1 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.20 EGO52278.1 - 2.3e-63 213.7 0.0 5.4e-39 133.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO52278.1 - 6.8e-27 94.1 0.0 2.1e-20 72.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EGO52278.1 - 1.1e-12 47.9 0.0 2.5e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EGO52278.1 - 1.2e-07 30.9 0.0 1.9e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EGO52278.1 - 3.6e-06 26.8 0.0 0.004 16.9 0.1 2.7 1 1 0 2 2 2 2 Phosphotransferase enzyme family PAS PF00989.19 EGO52278.1 - 0.00018 21.2 0.0 0.00044 20.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EGO52278.1 - 0.0008 19.7 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 PAS domain Kdo PF06293.9 EGO52278.1 - 0.025 13.6 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EGO52278.1 - 0.11 11.3 0.1 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 bZIP_1 PF00170.16 EGO52279.1 - 0.00036 20.4 9.1 0.00073 19.4 6.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGO52279.1 - 0.098 12.4 9.7 0.08 12.7 2.1 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF904 PF06005.7 EGO52279.1 - 0.96 9.7 5.7 0.15 12.3 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF904) eIF-3_zeta PF05091.7 EGO52280.1 - 1.5e-198 660.6 0.0 1.8e-198 660.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 EGO52280.1 - 0.013 14.9 0.1 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF569) DRMBL PF07522.9 EGO52281.1 - 8.5e-12 45.0 0.0 1.9e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EGO52281.1 - 1.1e-11 44.6 0.0 2.3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGO52281.1 - 0.046 13.3 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily PDEase_II PF02112.10 EGO52281.1 - 0.22 10.4 0.0 8.5 5.1 0.0 2.1 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II LSM PF01423.17 EGO52282.1 - 2.5e-15 55.7 1.1 3.8e-15 55.1 0.8 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGO52282.1 - 0.0013 18.6 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.3 EGO52282.1 - 0.0067 16.1 0.1 0.036 13.8 0.0 1.9 1 1 1 2 2 2 1 Gem-associated protein 7 (Gemin7) Ada3 PF10198.4 EGO52283.1 - 7.2e-46 155.1 0.0 7.2e-46 155.1 0.0 2.1 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 Mito_carr PF00153.22 EGO52284.1 - 8.2e-66 217.7 2.7 2.6e-22 78.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HTH_26 PF13443.1 EGO52285.1 - 0.16 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Sod_Fe_C PF02777.13 EGO52286.1 - 6.1e-11 42.1 0.0 9.4e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EGO52286.1 - 0.042 14.0 0.3 0.075 13.3 0.2 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain zf-RING_2 PF13639.1 EGO52287.1 - 1.5e-12 47.1 5.4 2.7e-12 46.2 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGO52287.1 - 3e-08 33.6 0.8 6.1e-08 32.6 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGO52287.1 - 1.2e-07 31.6 6.7 2.4e-07 30.6 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO52287.1 - 3.7e-07 29.6 6.3 7e-07 28.8 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO52287.1 - 1.6e-06 27.7 4.5 2.8e-06 26.9 3.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGO52287.1 - 5.6e-05 22.8 1.2 0.00011 21.9 0.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EGO52287.1 - 0.00015 21.3 6.5 0.00027 20.5 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGO52287.1 - 0.016 15.0 9.2 0.031 14.1 6.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGO52287.1 - 0.026 14.2 0.9 0.026 14.2 0.6 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.3 EGO52287.1 - 0.038 13.4 3.5 0.084 12.4 2.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.7 EGO52287.1 - 0.21 10.7 0.6 0.35 10.0 0.4 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger RINGv PF12906.2 EGO52287.1 - 0.31 11.1 6.5 0.52 10.4 4.5 1.4 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EGO52287.1 - 0.36 10.8 5.6 1.7 8.6 3.9 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain YdjO PF14169.1 EGO52287.1 - 0.36 10.3 1.6 3.1 7.3 0.7 2.3 2 0 0 2 2 2 0 Cold-inducible protein YdjO DUF1049 PF06305.6 EGO52287.1 - 0.44 10.0 2.3 1.1 8.7 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) zf-RING_4 PF14570.1 EGO52287.1 - 0.71 9.5 6.3 1.3 8.6 4.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EGO52287.1 - 2.1 8.1 5.8 4 7.2 4.0 1.5 1 0 0 1 1 1 0 PHD-finger Mito_fiss_reg PF05308.6 EGO52288.1 - 0.34 10.2 2.4 0.36 10.1 1.7 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Granulin PF00396.13 EGO52289.1 - 0.00069 19.6 4.2 0.00069 19.6 2.9 3.5 2 1 1 3 3 3 1 Granulin Podoplanin PF05808.6 EGO52289.1 - 0.0033 16.9 0.8 0.008 15.7 0.5 1.6 1 0 0 1 1 1 1 Podoplanin DUF912 PF06024.7 EGO52289.1 - 0.013 15.5 0.0 1.4 9.0 0.0 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Adeno_E3_CR2 PF02439.10 EGO52289.1 - 0.12 11.9 0.3 0.24 10.9 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SAM_2 PF07647.12 EGO52291.1 - 5.2e-09 35.8 0.0 1.2e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGO52291.1 - 2.2e-05 24.5 0.0 4.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EGO52291.1 - 8e-05 22.7 0.1 0.00039 20.5 0.1 2.2 1 1 0 1 1 1 1 PH domain Ste50p-SAM PF09235.5 EGO52291.1 - 0.015 15.3 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 Ste50p, sterile alpha motif PH_9 PF15410.1 EGO52291.1 - 0.1 12.7 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Fungal_trans_2 PF11951.3 EGO52293.1 - 2.2e-73 247.0 0.2 2.8e-73 246.7 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO52293.1 - 3.7e-06 26.7 9.3 6.2e-06 26.0 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop14 PF04147.7 EGO52294.1 - 1.8e-254 846.6 37.6 2.2e-254 846.3 26.0 1.1 1 0 0 1 1 1 1 Nop14-like family AAA_12 PF13087.1 EGO52296.1 - 2.4e-32 111.9 0.0 2.8e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain SMP PF04927.7 EGO52297.1 - 0.014 15.3 0.3 0.014 15.3 0.2 2.2 2 0 0 2 2 2 0 Seed maturation protein Adeno_PIX PF03955.9 EGO52297.1 - 0.43 11.1 7.9 3 8.3 0.1 3.2 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) Pkinase PF00069.20 EGO52298.1 - 5.1e-35 120.8 0.0 1.4e-20 73.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO52298.1 - 9.4e-13 47.8 0.0 0.00066 18.8 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 EGO52298.1 - 0.0035 17.0 0.0 0.019 14.6 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGO52298.1 - 0.014 14.4 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like CAP_GLY PF01302.20 EGO52299.1 - 4.8e-17 61.4 0.2 1.1e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 CAP-Gly domain Reo_sigmaC PF04582.7 EGO52299.1 - 0.38 9.8 8.6 0.14 11.2 1.0 2.8 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EGO52299.1 - 0.55 8.8 29.9 2 6.9 7.8 3.2 2 1 2 4 4 4 0 Spc7 kinetochore protein Glyco_hydro_4C PF11975.3 EGO52299.1 - 0.58 9.9 5.8 1.9 8.2 0.8 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain NPV_P10 PF05531.7 EGO52299.1 - 2 8.7 9.2 2.6 8.3 0.3 3.0 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Fe-S_assembly PF04384.8 EGO52299.1 - 3.4 8.0 6.5 0.57 10.5 0.1 3.0 3 0 0 3 3 3 0 Iron-sulphur cluster assembly BLOC1_2 PF10046.4 EGO52299.1 - 4.8 7.3 21.3 0.089 12.9 3.5 3.8 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 EGO52299.1 - 5 5.4 21.5 2.8 6.2 12.0 2.3 1 1 0 1 1 1 0 AAA domain DUF202 PF02656.10 EGO52300.1 - 3e-24 85.0 1.0 3e-24 85.0 0.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) K_channel_TID PF07941.6 EGO52300.1 - 0.00081 19.5 0.9 0.055 13.6 0.1 2.6 2 0 0 2 2 2 1 Potassium channel Kv1.4 tandem inactivation domain Aldo_ket_red PF00248.16 EGO52301.1 - 2.2e-56 190.7 0.0 2.4e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Amidohydro_2 PF04909.9 EGO52301.1 - 0.079 12.5 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase SHR3_chaperone PF08229.6 EGO52302.1 - 2.8e-78 261.3 0.1 3.3e-78 261.1 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 PMP22_Claudin PF00822.15 EGO52302.1 - 0.07 12.7 1.3 21 4.7 0.0 3.1 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin family Glyco_hydro_38 PF01074.17 EGO52303.1 - 2.5e-91 305.7 0.3 4.5e-91 304.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EGO52303.1 - 2.9e-83 280.2 1.6 6.5e-83 279.0 1.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EGO52303.1 - 2.1e-26 91.9 0.0 4.8e-26 90.7 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Resolvase PF00239.16 EGO52304.1 - 0.86 9.4 8.5 0.14 11.9 0.6 2.6 2 0 0 2 2 2 0 Resolvase, N terminal domain Daxx PF03344.10 EGO52304.1 - 3.2 6.1 27.4 2 6.8 8.3 2.1 2 0 0 2 2 2 0 Daxx Family MutS_V PF00488.16 EGO52306.1 - 6.3e-75 251.6 0.0 1e-74 250.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGO52306.1 - 2.3e-37 128.7 1.3 8.7e-37 126.8 0.9 2.0 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EGO52306.1 - 1.7e-21 76.3 0.0 4e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain I AAA_22 PF13401.1 EGO52306.1 - 0.01 15.9 0.0 2.6 8.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EGO52306.1 - 0.02 14.3 0.0 0.077 12.5 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EGO52306.1 - 0.028 14.3 0.0 0.56 10.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain Ribosomal_L10 PF00466.15 EGO52307.1 - 4.9e-25 87.3 0.1 1e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EGO52307.1 - 2.7e-16 59.7 9.3 4.9e-16 58.9 4.3 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein Phage_holin PF04688.8 EGO52307.1 - 0.064 12.7 0.2 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Phage lysis protein, holin VirE_N PF08800.5 EGO52307.1 - 0.14 11.9 0.0 0.42 10.3 0.0 1.7 2 0 0 2 2 2 0 VirE N-terminal domain WD40 PF00400.27 EGO52308.1 - 1.2e-05 25.0 0.5 0.38 10.7 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat CPSF_A PF03178.10 EGO52308.1 - 0.02 14.0 0.0 0.042 12.9 0.0 1.5 1 0 0 1 1 1 0 CPSF A subunit region CDC45 PF02724.9 EGO52308.1 - 0.19 9.7 3.9 0.31 9.0 2.7 1.3 1 0 0 1 1 1 0 CDC45-like protein BTB PF00651.26 EGO52309.1 - 7.8e-06 25.8 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DEAD PF00270.24 EGO52310.1 - 4.3e-18 65.3 0.0 1.2e-17 63.8 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO52310.1 - 2.5e-09 36.8 0.0 5.6e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 EGO52310.1 - 5.9e-05 23.1 0.0 0.00035 20.6 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain HTH_psq PF05225.11 EGO52310.1 - 0.012 15.1 0.0 0.036 13.6 0.0 1.8 1 0 0 1 1 1 0 helix-turn-helix, Psq domain ResIII PF04851.10 EGO52310.1 - 0.025 14.4 0.0 0.17 11.7 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-HC5HC2H_2 PF13832.1 EGO52311.1 - 7.9e-21 74.1 13.1 5.7e-19 68.1 1.0 4.1 3 0 0 3 3 3 3 PHD-zinc-finger like domain BAH PF01426.13 EGO52311.1 - 4.2e-17 61.9 0.0 8.9e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.1 EGO52311.1 - 9.6e-16 57.7 3.0 9.6e-16 57.7 2.1 5.1 5 0 0 5 5 5 1 PHD-like zinc-binding domain PHD PF00628.24 EGO52311.1 - 2.8e-11 42.9 53.5 5.9e-06 25.8 5.8 6.1 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.1 EGO52311.1 - 5.1e-09 35.3 4.6 5.1e-09 35.3 3.2 5.2 6 0 0 6 6 6 2 PHD-finger Prok-RING_1 PF14446.1 EGO52311.1 - 0.069 12.8 43.8 0.042 13.5 1.5 4.9 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 GATA PF00320.22 EGO52311.1 - 1.8 7.9 13.5 0.22 10.9 0.5 4.5 4 0 0 4 4 4 0 GATA zinc finger dCMP_cyt_deam_1 PF00383.17 EGO52313.1 - 5.2e-20 71.0 0.0 6.9e-20 70.5 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EGO52313.1 - 0.023 14.3 0.3 0.16 11.5 0.2 2.0 1 1 0 1 1 1 0 APOBEC-like N-terminal domain Bd3614-deam PF14439.1 EGO52313.1 - 0.043 13.6 0.3 0.22 11.3 0.1 2.0 1 1 1 2 2 2 0 Bd3614-like deaminase DnaJ PF00226.26 EGO52314.1 - 7.4e-26 89.6 2.2 1.6e-25 88.6 1.5 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGO52314.1 - 1e-21 76.6 0.1 7.3e-19 67.4 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EGO52314.1 - 2.6e-14 53.0 18.4 6.4e-14 51.7 12.8 1.7 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EGO52314.1 - 0.011 15.3 10.1 0.089 12.4 1.9 2.4 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DARPP-32 PF05395.7 EGO52314.1 - 0.082 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF2614 PF11023.3 EGO52314.1 - 0.13 12.0 5.3 1 9.1 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) zinc-ribbons_6 PF07191.7 EGO52314.1 - 0.25 11.1 6.6 2.2 8.1 1.2 2.5 2 0 0 2 2 2 0 zinc-ribbons zf-RING_3 PF14369.1 EGO52314.1 - 0.37 10.8 2.5 27 4.8 0.1 3.3 3 0 0 3 3 3 0 zinc-finger Abhydrolase_6 PF12697.2 EGO52315.1 - 6.7e-13 49.0 0.2 4.6e-12 46.3 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO52315.1 - 4.2e-09 36.3 0.0 5.6e-08 32.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO52315.1 - 9.5e-09 35.1 0.0 1.9e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EGO52315.1 - 0.0067 15.8 0.0 0.025 13.9 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EGO52315.1 - 0.0093 15.2 0.0 0.14 11.3 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S28 PF05577.7 EGO52315.1 - 0.017 13.6 0.0 0.028 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Esterase PF00756.15 EGO52315.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Methyltransf_7 PF03492.10 EGO52315.1 - 0.1 11.3 0.0 1 8.0 0.0 2.0 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase SNARE_assoc PF09335.6 EGO52317.1 - 8.7e-12 45.3 8.5 8.7e-12 45.3 5.9 2.4 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF1158 PF06643.6 EGO52317.1 - 0.016 15.5 2.1 0.11 12.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1158) DUF1700 PF08006.6 EGO52317.1 - 0.72 9.1 4.5 1.4 8.2 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF2721 PF11026.3 EGO52317.1 - 1.4 8.5 8.5 0.29 10.7 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF1771 PF08590.5 EGO52318.1 - 3.3e-13 49.4 9.4 6.5e-13 48.4 6.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EGO52318.1 - 1.2e-08 35.0 0.0 3.8e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 EGO52318.1 - 2.5e-06 27.0 1.5 0.004 16.7 0.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 EGO52318.1 - 0.0021 18.1 0.1 0.055 13.6 0.0 2.3 2 0 0 2 2 2 1 HBS1 N-terminus Scaffolding_pro PF11418.3 EGO52318.1 - 0.029 14.6 0.1 0.053 13.8 0.1 1.4 1 0 0 1 1 1 0 Phi29 scaffolding protein Cupin_8 PF13621.1 EGO52319.1 - 1.2e-19 70.8 0.4 7.2e-19 68.2 0.3 2.0 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EGO52319.1 - 1.2e-09 38.3 0.1 5e-09 36.3 0.1 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 EGO52319.1 - 1.8e-05 24.3 0.2 4.7e-05 23.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.7 EGO52319.1 - 0.0069 15.6 0.0 0.032 13.4 0.0 1.9 2 0 0 2 2 2 1 Cupin superfamily protein LPAM_1 PF08139.7 EGO52320.1 - 0.45 10.8 1.8 2.1 8.6 1.2 2.2 1 1 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DEAD PF00270.24 EGO52321.1 - 4.9e-44 149.8 1.8 7.1e-44 149.2 0.7 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO52321.1 - 1.4e-27 95.3 0.3 6.2e-27 93.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO52321.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EGO52321.1 - 0.0054 16.3 0.1 0.016 14.7 0.0 1.8 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.1 EGO52321.1 - 0.024 13.7 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 EGO52321.1 - 0.027 14.6 0.2 0.12 12.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGO52321.1 - 0.031 14.0 0.1 0.1 12.3 0.1 1.9 1 1 0 1 1 1 0 Part of AAA domain tRNA-synt_1b PF00579.20 EGO52321.1 - 0.076 12.1 0.0 0.3 10.1 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) CobA_CobO_BtuR PF02572.10 EGO52321.1 - 0.077 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Fanconi_A PF03511.9 EGO52321.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein RRM_1 PF00076.17 EGO52322.1 - 2.3e-16 59.1 0.0 4.3e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO52322.1 - 6.1e-13 48.5 0.0 1.1e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO52322.1 - 1.3e-06 28.1 0.0 2.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EGO52322.1 - 0.00021 21.6 20.7 0.00021 21.6 14.3 4.4 3 2 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 DUF1932 PF09130.6 EGO52323.1 - 2.7e-20 71.8 0.0 6.7e-20 70.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.12 EGO52323.1 - 3e-08 33.9 0.1 1.2e-07 32.0 0.2 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EGO52323.1 - 3.4e-08 33.5 0.0 6.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EGO52323.1 - 0.0013 17.9 0.1 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EGO52323.1 - 0.0041 16.4 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Rossmann-like PF10727.4 EGO52323.1 - 0.0088 15.7 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 Rossmann-like domain F-box-like PF12937.2 EGO52326.1 - 0.00069 19.2 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like DUF2415 PF10313.4 EGO52326.1 - 0.043 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) AP_endonuc_2 PF01261.19 EGO52327.1 - 1.8e-30 105.8 0.0 2.5e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.7 EGO52328.1 - 4e-42 142.9 0.8 6.7e-42 142.2 0.6 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EGO52328.1 - 1.5e-12 47.2 0.0 3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO52328.1 - 0.04 13.0 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Enolase_C PF00113.17 EGO52330.1 - 1.1e-152 507.2 0.1 1.3e-152 506.8 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EGO52330.1 - 5.4e-58 194.6 0.0 9e-58 193.9 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 EGO52330.1 - 0.0015 17.5 0.2 0.052 12.4 0.1 2.7 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EGO52330.1 - 0.024 15.1 0.0 0.063 13.8 0.0 1.8 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Peptidase_M1 PF01433.15 EGO52332.1 - 8.2e-144 479.4 0.0 1.4e-143 478.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EGO52332.1 - 2.6e-95 319.4 0.0 4.6e-95 318.5 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EGO52332.1 - 3.3e-20 72.4 0.2 7.5e-20 71.2 0.2 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Kelch_3 PF13415.1 EGO52333.1 - 9.8e-29 98.8 10.0 3.8e-10 39.6 0.1 6.4 7 0 0 7 7 7 4 Galactose oxidase, central domain DUF4110 PF13422.1 EGO52333.1 - 2.4e-28 97.7 0.1 2.4e-28 97.7 0.1 4.1 4 1 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 EGO52333.1 - 8.7e-23 79.8 14.3 4.7e-05 23.0 0.3 6.6 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EGO52333.1 - 6.7e-20 70.6 1.7 7.4e-07 28.9 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EGO52333.1 - 2.4e-17 62.2 2.8 6.2e-06 26.1 0.1 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 EGO52333.1 - 4.1e-15 54.8 0.7 0.047 13.4 0.0 6.1 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EGO52333.1 - 4.7e-14 51.6 0.2 3.2e-06 26.5 0.0 5.2 5 0 0 5 5 5 3 Kelch motif DUF3534 PF12053.3 EGO52333.1 - 0.0062 16.4 0.3 0.024 14.5 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3534) WLM PF08325.5 EGO52334.1 - 6.1e-43 146.8 0.2 9.6e-42 142.9 0.1 2.7 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 EGO52334.1 - 4.4e-08 33.1 0.5 1.5e-07 31.4 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function DUF45 Thioredoxin PF00085.15 EGO52337.1 - 4.1e-62 206.3 9.6 1.9e-31 107.8 0.2 3.9 4 1 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EGO52337.1 - 1.6e-56 191.0 3.6 8.4e-43 146.3 0.3 3.4 2 2 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGO52337.1 - 8.4e-12 44.9 0.3 2.2e-05 24.4 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EGO52337.1 - 1.8e-11 44.0 0.3 0.00075 19.5 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EGO52337.1 - 2.3e-11 43.8 6.0 0.00019 21.6 0.1 4.5 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EGO52337.1 - 4.5e-09 36.0 2.8 0.0056 16.3 0.1 3.6 3 0 0 3 3 3 3 AhpC/TSA family Redoxin PF08534.5 EGO52337.1 - 2.1e-08 33.8 7.4 0.00029 20.3 0.0 3.5 4 0 0 4 4 4 3 Redoxin Calsequestrin PF01216.12 EGO52337.1 - 6e-06 25.2 2.6 6e-06 25.2 1.8 2.0 2 1 0 2 2 2 1 Calsequestrin ERp29_N PF07912.8 EGO52337.1 - 3.4e-05 23.7 0.8 1.6 8.6 0.0 4.0 3 1 0 3 3 3 2 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 EGO52337.1 - 0.00062 19.8 3.7 0.93 9.4 0.0 4.2 3 1 0 3 3 3 2 Thioredoxin DSBA PF01323.15 EGO52337.1 - 0.019 14.5 0.8 2.9 7.3 0.1 3.1 3 1 0 3 3 3 0 DSBA-like thioredoxin domain RPT PF13446.1 EGO52337.1 - 0.51 9.7 5.8 1.6 8.1 0.0 3.4 4 0 0 4 4 4 0 A repeated domain in UCH-protein zf-HIT PF04438.11 EGO52339.1 - 2.8e-09 36.4 5.5 4.2e-09 35.8 3.8 1.3 1 0 0 1 1 1 1 HIT zinc finger Nif11 PF07862.6 EGO52339.1 - 0.033 14.1 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function Mon1 PF03164.9 EGO52340.1 - 5.7e-109 364.4 0.0 8.8e-109 363.8 0.0 1.3 1 0 0 1 1 1 1 Trafficking protein Mon1 Orbi_VP7 PF00897.12 EGO52340.1 - 0.21 10.5 0.4 2.6 6.8 0.1 2.1 2 0 0 2 2 2 0 Orbivirus inner capsid protein VP7 Dopey_N PF04118.9 EGO52341.1 - 3.8e-118 393.7 0.0 1.6e-117 391.6 0.0 2.1 3 0 0 3 3 3 1 Dopey, N-terminal HEAT_EZ PF13513.1 EGO52341.1 - 0.013 16.0 6.7 11 6.6 0.0 5.9 5 0 0 5 5 5 0 HEAT-like repeat MtmB PF05369.7 EGO52341.1 - 0.13 10.4 0.0 0.19 9.8 0.0 1.1 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB Methyltransf_15 PF09445.5 EGO52342.1 - 8.4e-58 194.5 0.0 1.2e-57 194.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 EGO52342.1 - 0.00014 21.5 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 EGO52342.1 - 0.00014 22.3 1.7 0.00018 22.0 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO52342.1 - 0.00018 21.5 0.0 0.0005 20.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGO52342.1 - 0.0057 16.2 0.0 0.012 15.1 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein RdgC PF04381.7 EGO52342.1 - 0.045 12.6 0.9 0.077 11.9 0.6 1.3 1 0 0 1 1 1 0 Putative exonuclease, RdgC Cons_hypoth95 PF03602.10 EGO52342.1 - 0.11 11.8 0.0 0.39 10.0 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein 95 HGTP_anticodon2 PF12745.2 EGO52342.1 - 0.9 8.6 6.1 1.4 8.0 4.2 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs GRASP55_65 PF04495.9 EGO52343.1 - 3.9e-48 162.9 0.0 3.9e-47 159.7 0.0 2.3 2 1 1 3 3 3 1 GRASP55/65 PDZ-like domain DAD PF02109.11 EGO52344.1 - 6.6e-38 129.2 0.0 1e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 DAD family Med3 PF11593.3 EGO52344.1 - 0.007 15.6 10.3 0.0075 15.5 7.1 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal TrbL PF04610.9 EGO52344.1 - 0.016 14.8 1.7 0.022 14.4 1.2 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Mucin PF01456.12 EGO52344.1 - 0.054 13.2 24.2 0.1 12.3 16.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Hamartin PF04388.7 EGO52344.1 - 2.1 6.9 5.1 3.3 6.2 3.5 1.3 1 0 0 1 1 1 0 Hamartin protein CAF-1_p60_C PF15512.1 EGO52344.1 - 4.6 7.6 16.6 0.87 9.9 8.9 1.6 2 0 0 2 2 2 0 Chromatin assembly factor complex 1 subunit p60, C-terminal DUF202 PF02656.10 EGO52345.1 - 0.00039 20.5 3.4 0.00073 19.6 0.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Zn_clus PF00172.13 EGO52346.1 - 2.5e-07 30.4 7.9 3.9e-07 29.8 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EGO52350.1 - 7.5e-71 238.3 0.0 1.2e-70 237.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO52350.1 - 3.8e-33 114.6 0.0 3.9e-31 108.0 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO52350.1 - 0.00044 19.2 1.1 0.4 9.6 0.0 2.8 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 EGO52350.1 - 0.0035 17.1 0.7 0.21 11.3 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 EGO52350.1 - 0.0097 15.2 0.5 0.02 14.2 0.3 1.5 1 0 0 1 1 1 1 RIO1 family AAA_11 PF13086.1 EGO52351.1 - 1e-26 93.9 0.0 8.4e-26 90.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EGO52351.1 - 1.4e-23 83.3 0.0 1.1e-12 47.7 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 EGO52351.1 - 1.7e-07 30.8 0.1 4.7e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGO52351.1 - 6.8e-07 29.0 0.0 2.8e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EGO52351.1 - 0.0021 17.6 0.0 0.42 10.0 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EGO52351.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 EGO52351.1 - 0.067 12.5 0.0 0.33 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.12 EGO52351.1 - 0.31 9.6 0.0 0.51 8.8 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Vanabin-2 PF11437.3 EGO52351.1 - 0.79 9.7 15.5 1.9 8.5 10.8 1.6 1 0 0 1 1 1 0 Vanadium-binding protein 2 Dyp_perox PF04261.7 EGO52352.1 - 4.1e-09 35.6 0.0 4.3e-07 28.9 0.0 3.0 3 0 0 3 3 3 2 Dyp-type peroxidase family DUF1929 PF09118.6 EGO52353.1 - 1.7e-25 88.9 0.0 3.2e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.20 EGO52353.1 - 2.4e-18 66.1 2.4 2.6e-18 66.0 0.1 2.1 2 0 0 2 2 2 1 F5/8 type C domain Kelch_6 PF13964.1 EGO52353.1 - 7.7e-18 63.8 0.6 6.2e-06 26.1 0.0 4.9 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.20 EGO52353.1 - 1e-13 50.5 0.3 0.00026 20.4 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 EGO52353.1 - 7.5e-11 41.6 8.3 0.0001 21.9 0.0 5.4 5 1 0 5 5 5 2 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.6 EGO52353.1 - 2.9e-10 39.6 0.2 0.00058 19.0 0.0 2.5 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.10 EGO52353.1 - 6.4e-10 38.4 0.0 0.017 14.8 0.0 4.5 3 1 0 3 3 3 3 Kelch motif Kelch_3 PF13415.1 EGO52353.1 - 4.8e-05 23.4 0.9 0.5 10.5 0.0 4.4 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EGO52353.1 - 0.056 13.4 1.8 6.8 6.7 0.0 3.6 4 0 0 4 4 4 0 Kelch motif WD40 PF00400.27 EGO52354.1 - 1.3e-18 66.1 6.2 0.00068 19.4 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat MFS_1 PF07690.11 EGO52355.1 - 5.3e-11 41.8 33.9 2.8e-08 32.8 7.8 3.0 3 0 0 3 3 3 3 Major Facilitator Superfamily zf-met PF12874.2 EGO52357.1 - 6.7e-05 22.9 0.8 0.51 10.6 0.1 3.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EGO52357.1 - 0.022 15.0 14.6 0.49 10.8 0.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger DDE_3 PF13358.1 EGO52357.1 - 0.036 13.7 0.1 0.036 13.7 0.1 2.3 2 1 0 2 2 2 0 DDE superfamily endonuclease zf-H2C2_2 PF13465.1 EGO52357.1 - 0.079 13.2 0.2 0.079 13.2 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.21 EGO52357.1 - 0.19 12.1 0.3 0.19 12.1 0.2 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type Med15 PF09606.5 EGO52357.1 - 4.7 5.2 35.6 7.1 4.6 24.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Fungal_trans PF04082.13 EGO52358.1 - 1.1e-22 80.2 2.2 2.7e-22 78.8 0.6 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO52358.1 - 7.8e-10 38.4 11.8 1.6e-09 37.5 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brr6_like_C_C PF10104.4 EGO52359.1 - 3.8e-42 143.0 1.1 4.8e-42 142.6 0.8 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Med26 PF08711.6 EGO52360.1 - 9.1e-10 37.9 0.0 1.8e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Herpes_BBRF1 PF04793.7 EGO52360.1 - 0.15 10.7 0.1 0.21 10.3 0.1 1.1 1 0 0 1 1 1 0 BRRF1-like protein MAGE_N PF12440.3 EGO52361.1 - 0.2 11.9 4.7 0.27 11.5 3.3 1.1 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal DUF605 PF04652.11 EGO52362.1 - 1.1 8.5 12.5 1.4 8.2 8.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF3470 PF11953.3 EGO52365.1 - 0.0076 15.8 0.1 0.03 13.9 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3470) Nop14 PF04147.7 EGO52365.1 - 0.034 12.1 9.9 0.047 11.6 6.8 1.4 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EGO52365.1 - 0.16 11.4 13.2 0.42 10.1 9.1 1.6 1 0 0 1 1 1 0 Nucleoplasmin TFIIA PF03153.8 EGO52365.1 - 4.9 6.9 26.1 13 5.5 18.1 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.14 EGO52365.1 - 9.7 6.6 16.6 0.2 12.1 5.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Tyrosinase PF00264.15 EGO52366.1 - 2.7e-45 155.2 0.5 3.6e-45 154.8 0.4 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Myb_DNA-bind_6 PF13921.1 EGO52367.1 - 3.3e-32 110.3 11.4 2.7e-14 53.0 0.6 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGO52367.1 - 1.3e-29 101.9 7.3 2.5e-11 43.4 0.6 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EGO52367.1 - 0.00011 21.9 3.4 1.1 9.1 1.1 3.3 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EGO52367.1 - 0.0035 17.1 0.0 0.57 10.0 0.0 2.9 3 1 0 3 3 3 1 Rap1 Myb domain Myb_DNA-bind_4 PF13837.1 EGO52367.1 - 0.023 14.8 11.1 0.094 12.8 0.3 3.9 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF3439 PF11921.3 EGO52367.1 - 1.5 8.6 23.8 0.35 10.6 8.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF3433 PF11915.3 EGO52368.1 - 0.024 14.7 0.1 0.055 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) PQ-loop PF04193.9 EGO52369.1 - 4.6e-39 131.7 15.9 1.6e-21 75.6 0.3 3.2 3 1 1 4 4 4 2 PQ loop repeat SLAIN PF15301.1 EGO52369.1 - 0.038 13.1 7.4 0.051 12.7 5.1 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family S1-P1_nuclease PF02265.11 EGO52370.1 - 1.7e-76 257.2 0.0 1.9e-76 257.0 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease CDP-OH_P_transf PF01066.16 EGO52372.1 - 9.7e-18 64.3 7.2 2.6e-17 62.9 4.9 1.9 1 1 1 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3441 PF11923.3 EGO52373.1 - 8.5e-37 125.2 0.1 3.5e-36 123.2 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EGO52373.1 - 3.7e-36 124.6 9.8 3.7e-36 124.6 6.8 2.6 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EGO52373.1 - 1.6e-24 85.6 0.0 3.6e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) eIF-5a PF01287.15 EGO52374.1 - 2.8e-07 30.3 0.0 4.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Peptidase_C1_2 PF03051.10 EGO52375.1 - 6e-153 509.4 0.0 7e-153 509.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EGO52375.1 - 3.6e-08 33.5 0.0 0.0007 19.5 0.0 2.5 2 0 0 2 2 2 2 Papain family cysteine protease DUF3818 PF12825.2 EGO52381.1 - 1.7e-137 457.7 6.4 2.5e-137 457.1 4.4 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EGO52381.1 - 1.6e-42 144.3 1.1 4.3e-42 142.9 0.8 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EGO52381.1 - 1e-13 51.0 0.7 1.7e-12 47.1 0.0 2.8 2 0 0 2 2 2 1 PX domain FAD_binding_2 PF00890.19 EGO52382.1 - 1.7e-123 412.5 4.0 2.1e-123 412.2 2.8 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EGO52382.1 - 1.7e-48 163.7 0.3 2.5e-48 163.1 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EGO52382.1 - 1.4e-07 31.5 0.0 0.0023 17.8 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO52382.1 - 5.2e-06 25.7 0.3 0.0067 15.5 0.0 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EGO52382.1 - 2.4e-05 23.4 1.0 0.0099 14.7 1.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EGO52382.1 - 0.0008 18.4 0.2 0.0038 16.1 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGO52382.1 - 0.0034 16.4 0.6 0.0076 15.3 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EGO52382.1 - 0.082 11.3 1.3 0.24 9.8 0.4 2.1 2 0 0 2 2 2 0 HI0933-like protein DUF3405 PF11885.3 EGO52384.1 - 1e-219 729.9 3.5 1.2e-219 729.6 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) EMP24_GP25L PF01105.19 EGO52385.1 - 3e-43 147.6 0.1 3.5e-43 147.4 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SpoU_methylase PF00588.14 EGO52385.1 - 0.034 14.0 0.0 0.72 9.7 0.0 2.1 1 1 1 2 2 2 0 SpoU rRNA Methylase family Arf PF00025.16 EGO52386.1 - 1.3e-78 262.2 0.1 1.5e-78 262.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGO52386.1 - 1.8e-14 53.3 0.0 2.2e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGO52386.1 - 8.8e-13 47.9 0.0 9.4e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EGO52386.1 - 1.1e-12 47.3 1.6 1.2e-09 37.3 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGO52386.1 - 3.6e-11 42.6 0.0 4.1e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGO52386.1 - 1.1e-08 35.5 0.0 1.5e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGO52386.1 - 6.2e-06 26.1 0.0 8.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EGO52386.1 - 0.007 15.4 0.3 0.012 14.6 0.2 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EGO52386.1 - 0.0081 15.6 0.1 0.062 12.7 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EGO52386.1 - 0.023 14.5 0.2 0.063 13.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain E1-E2_ATPase PF00122.15 EGO52387.1 - 2.1e-54 184.0 0.2 4.7e-54 182.8 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.21 EGO52387.1 - 2.2e-46 155.8 2.0 7.1e-13 48.4 0.2 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 EGO52387.1 - 2.6e-45 155.4 1.8 5.8e-45 154.3 1.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGO52387.1 - 1.9e-14 54.2 0.0 4.3e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGO52387.1 - 6.3e-07 29.2 0.6 8.8e-05 22.2 0.2 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase PCI PF01399.22 EGO52388.1 - 2.1e-05 24.7 0.0 0.00045 20.4 0.0 2.3 2 0 0 2 2 2 1 PCI domain Zip PF02535.17 EGO52388.1 - 0.1 11.6 0.3 0.16 10.9 0.1 1.4 2 0 0 2 2 2 0 ZIP Zinc transporter BORG_CEP PF14957.1 EGO52388.1 - 8.7 7.2 8.1 4.8 8.1 0.0 3.0 3 0 0 3 3 3 0 Cdc42 effector RGS PF00615.14 EGO52389.1 - 2.4e-11 43.7 0.0 3e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Ribosomal_L31e PF01198.14 EGO52390.1 - 1.7e-35 120.5 2.4 2.2e-35 120.2 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e UQ_con PF00179.21 EGO52391.1 - 1.8e-08 33.8 0.0 2.2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.20 EGO52392.1 - 6e-60 202.5 0.0 7.7e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO52392.1 - 3.3e-29 101.7 0.0 4.9e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO52392.1 - 6.3e-07 28.6 0.0 9.1e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO52392.1 - 0.00018 21.3 0.0 0.63 9.7 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGO52392.1 - 0.015 14.3 0.0 0.032 13.2 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SprT-like PF10263.4 EGO52393.1 - 7.3e-14 51.7 0.1 7.3e-14 51.7 0.1 2.5 2 0 0 2 2 2 1 SprT-like family Neur_chan_memb PF02932.11 EGO52393.1 - 0.89 9.3 2.8 1.4 8.7 1.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region F-box-like PF12937.2 EGO52394.1 - 2.1e-09 36.9 0.1 5.6e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO52394.1 - 3.1e-07 29.8 0.5 7e-07 28.7 0.4 1.7 1 0 0 1 1 1 1 F-box domain DUF1772 PF08592.6 EGO52397.1 - 7.7e-11 41.8 1.8 4.6e-07 29.6 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) Nop14 PF04147.7 EGO52397.1 - 3.4 5.4 6.0 4.8 4.9 4.2 1.2 1 0 0 1 1 1 0 Nop14-like family Herpes_capsid PF06112.6 EGO52398.1 - 1.1 9.2 8.8 1.1 9.2 6.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein EGF_CA PF07645.10 EGO52398.1 - 3.8 7.5 8.0 7.7 6.5 4.3 2.1 1 1 1 2 2 2 0 Calcium-binding EGF domain Pyr_redox_2 PF07992.9 EGO52399.1 - 4.4e-30 105.0 0.0 9.9e-30 103.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO52399.1 - 1.5e-18 66.9 4.3 1.2e-16 60.8 0.8 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO52399.1 - 2.7e-12 47.1 0.2 2.9e-07 30.7 0.0 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EGO52399.1 - 1.9e-06 28.0 0.3 0.00035 20.7 0.1 2.6 2 2 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.19 EGO52399.1 - 7e-06 25.1 2.4 0.37 9.6 0.1 3.6 3 1 1 4 4 4 3 FAD dependent oxidoreductase Thi4 PF01946.12 EGO52399.1 - 1.9e-05 23.8 0.2 0.00082 18.5 0.0 2.4 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 EGO52399.1 - 0.00015 20.8 0.2 0.016 14.1 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGO52399.1 - 0.00016 21.5 0.1 0.069 13.1 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EGO52399.1 - 0.00018 20.5 4.5 0.34 9.7 0.3 4.2 3 2 1 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EGO52399.1 - 0.0022 17.0 1.5 3.2 6.7 0.0 3.1 2 1 1 3 3 3 2 FAD binding domain FAD_oxidored PF12831.2 EGO52399.1 - 0.0044 16.1 0.2 0.13 11.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGO52399.1 - 0.0059 15.1 0.9 1.1 7.6 0.1 3.1 2 1 1 3 3 3 1 HI0933-like protein Shikimate_DH PF01488.15 EGO52399.1 - 0.0066 16.5 0.6 3.4 7.7 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EGO52399.1 - 0.0091 14.8 7.7 0.082 11.7 0.3 3.2 3 1 0 4 4 4 2 FAD binding domain Trp_halogenase PF04820.9 EGO52399.1 - 0.012 14.2 0.1 0.31 9.6 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase ThiF PF00899.16 EGO52399.1 - 0.09 12.5 0.0 11 5.8 0.0 2.9 3 0 0 3 3 3 0 ThiF family NAD_binding_9 PF13454.1 EGO52399.1 - 0.11 12.2 0.2 39 3.9 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding ADH_zinc_N PF00107.21 EGO52400.1 - 3e-34 117.3 1.3 4.6e-34 116.7 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO52400.1 - 8e-13 49.3 0.5 2.1e-12 48.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO52400.1 - 9.1e-07 28.6 0.0 3.4e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EGO52400.1 - 0.0021 17.6 2.6 0.069 12.7 0.8 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EGO52400.1 - 0.025 14.5 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain zf-CCCH PF00642.19 EGO52401.1 - 1.7e-16 59.4 32.7 1e-06 28.2 0.2 5.3 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGO52401.1 - 0.027 14.4 0.2 0.027 14.4 0.2 5.5 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type Activator_LAG-3 PF11498.3 EGO52401.1 - 0.043 12.5 12.4 0.06 12.0 8.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF1776 PF08643.5 EGO52402.1 - 8.8e-119 396.0 0.0 1.1e-118 395.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Flavi_M PF01004.14 EGO52402.1 - 0.00069 19.0 0.1 0.0017 17.7 0.0 1.6 1 0 0 1 1 1 1 Flavivirus envelope glycoprotein M Methyltransf_31 PF13847.1 EGO52403.1 - 1.5e-14 53.8 0.0 2e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO52403.1 - 1.4e-11 44.7 0.0 2.8e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO52403.1 - 2.5e-10 40.6 0.1 1.2e-09 38.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO52403.1 - 7.8e-10 39.3 0.0 1.5e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO52403.1 - 1.5e-08 34.9 0.0 2.3e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO52403.1 - 6e-07 29.5 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO52403.1 - 7.6e-07 28.9 0.0 1.5e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 EGO52403.1 - 4.4e-06 26.3 0.0 1.1e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 MTS PF05175.9 EGO52403.1 - 7.7e-06 25.3 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EGO52403.1 - 0.00027 20.0 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 EGO52403.1 - 0.0003 19.9 0.0 0.00078 18.6 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EGO52403.1 - 0.00045 19.9 0.0 0.00073 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGO52403.1 - 0.0022 17.5 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SnoaL_4 PF13577.1 EGO52403.1 - 0.003 17.4 0.7 0.015 15.1 0.0 2.2 1 1 2 3 3 3 1 SnoaL-like domain DREV PF05219.7 EGO52403.1 - 0.0073 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.8 EGO52403.1 - 0.016 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Amidase PF01425.16 EGO52404.1 - 9.4e-86 288.3 0.0 1.1e-85 288.0 0.0 1.1 1 0 0 1 1 1 1 Amidase WD40 PF00400.27 EGO52405.1 - 1.6e-22 78.4 11.2 1.8e-08 33.9 0.0 7.0 8 0 0 8 8 8 4 WD domain, G-beta repeat HIRA_B PF09453.5 EGO52405.1 - 0.00039 19.8 0.2 0.00039 19.8 0.1 2.5 3 0 0 3 3 3 1 HIRA B motif eIF2A PF08662.6 EGO52405.1 - 0.00078 19.2 0.2 0.29 10.8 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF4185 PF13810.1 EGO52406.1 - 0.056 12.3 0.0 0.079 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) ABC_tran PF00005.22 EGO52407.1 - 9.2e-53 178.2 0.1 2.1e-30 105.7 0.1 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGO52407.1 - 8.7e-32 110.6 26.2 2.7e-19 69.6 7.4 4.1 4 0 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.14 EGO52407.1 - 2.1e-08 33.6 4.2 0.00041 19.6 0.5 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EGO52407.1 - 4.7e-06 26.1 0.0 0.0089 15.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGO52407.1 - 7.2e-05 22.8 1.4 0.019 14.9 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 EGO52407.1 - 0.00018 21.5 6.0 0.87 9.4 0.0 5.2 4 2 1 5 5 5 1 AAA domain T2SE PF00437.15 EGO52407.1 - 0.00019 20.4 0.0 0.097 11.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 EGO52407.1 - 0.00059 19.3 1.0 1.1 8.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EGO52407.1 - 0.0059 16.9 3.4 0.11 12.7 0.8 2.6 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGO52407.1 - 0.01 15.0 0.4 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 EGO52407.1 - 0.012 16.1 0.3 5.2 7.5 0.1 2.8 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 EGO52407.1 - 0.012 15.5 0.3 0.41 10.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 EGO52407.1 - 0.014 14.9 0.3 2.9 7.4 0.0 3.0 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EGO52407.1 - 0.035 14.0 0.0 4.6 7.2 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EGO52407.1 - 0.035 14.2 0.3 34 4.5 0.1 3.4 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.4 EGO52407.1 - 0.047 12.6 0.1 0.71 8.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 EGO52407.1 - 0.12 11.4 0.1 4.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.12 EGO52407.1 - 0.22 11.3 4.3 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF3599 PF12206.3 EGO52407.1 - 0.29 11.4 0.0 0.68 10.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) dCMP_cyt_deam_1 PF00383.17 EGO52408.1 - 9.3e-13 47.7 1.0 1.3e-11 44.0 0.7 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EGO52408.1 - 2.4e-05 24.3 0.6 0.0054 16.7 0.2 3.0 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region FYVE PF01363.16 EGO52409.1 - 7e-22 77.1 0.7 1.3e-21 76.2 0.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 EGO52409.1 - 0.0051 16.6 1.6 0.01 15.7 1.1 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-DHHC PF01529.15 EGO52409.1 - 0.042 13.2 1.1 0.083 12.2 0.7 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase Prok-RING_2 PF14445.1 EGO52409.1 - 0.14 12.1 2.5 0.28 11.1 1.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Elf1 PF05129.8 EGO52409.1 - 0.52 10.0 5.1 0.095 12.4 1.0 1.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like adh_short PF00106.20 EGO52410.1 - 7.5e-22 78.0 0.7 1e-21 77.5 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO52410.1 - 9.2e-17 61.6 0.3 4.9e-16 59.2 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO52410.1 - 6.9e-08 32.3 0.2 9.5e-08 31.9 0.1 1.1 1 0 0 1 1 1 1 KR domain PQ-loop PF04193.9 EGO52412.1 - 1.2e-21 75.9 8.9 5.5e-14 51.4 1.2 2.8 3 0 0 3 3 3 2 PQ loop repeat Sulfatase PF00884.18 EGO52413.1 - 3.8e-56 190.5 0.0 4.9e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EGO52413.1 - 1.9e-21 75.5 0.3 5e-21 74.2 0.2 1.8 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EGO52413.1 - 2.5e-09 36.9 0.0 7.5e-09 35.3 0.0 1.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EGO52413.1 - 0.03 12.7 0.0 0.048 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Med8 PF10232.4 EGO52414.1 - 1.9e-23 83.1 12.6 3.8e-22 78.9 8.7 2.0 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 YPEB PF14620.1 EGO52414.1 - 0.021 13.8 0.2 0.032 13.2 0.2 1.2 1 0 0 1 1 1 0 YpeB sporulation Urb2 PF10441.4 EGO52414.1 - 0.023 14.3 0.2 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 Urb2/Npa2 family DUF1759 PF03564.10 EGO52414.1 - 0.033 13.9 0.9 0.25 11.1 0.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) SSXT PF05030.7 EGO52414.1 - 0.046 13.2 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 SSXT protein (N-terminal region) FUSC-like PF12805.2 EGO52414.1 - 0.12 11.2 0.8 0.21 10.4 0.3 1.5 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS PBP1_TM PF14812.1 EGO52414.1 - 0.15 12.3 13.9 1.5 9.1 2.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BTV_NS2 PF04514.7 EGO52414.1 - 0.31 9.8 4.7 0.44 9.3 3.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CENP-B_dimeris PF09026.5 EGO52414.1 - 0.63 10.3 14.3 0.52 10.5 2.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EGO52414.1 - 0.83 9.1 15.0 1.3 8.5 3.5 2.2 2 0 0 2 2 2 0 Nucleoplasmin Acyl_transf_3 PF01757.17 EGO52417.1 - 2.1e-32 112.2 12.6 3.6e-32 111.5 8.7 1.4 1 1 0 1 1 1 1 Acyltransferase family GFA PF04828.9 EGO52418.1 - 6.3e-16 58.1 1.9 1.1e-15 57.3 1.3 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 EGO52418.1 - 6.5 6.7 10.1 0.28 11.1 2.0 2.3 2 0 0 2 2 2 0 Cysteine-rich CWC YadA_anchor PF03895.10 EGO52419.1 - 0.95 9.5 16.8 1.5 8.8 2.9 3.1 2 1 1 3 3 3 0 YadA-like C-terminal region RNase_P_p30 PF01876.11 EGO52420.1 - 2e-44 150.4 0.0 3e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 DUF155 PF02582.9 EGO52422.1 - 6.2e-59 198.8 0.1 9.6e-59 198.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Abhydro_lipase PF04083.11 EGO52423.1 - 1.3e-19 69.2 0.0 3.1e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EGO52423.1 - 6.2e-05 22.9 0.4 0.00014 21.8 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO52423.1 - 0.00062 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO52423.1 - 0.0076 15.8 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AAA PF00004.24 EGO52424.1 - 4e-49 166.1 0.0 1.8e-43 147.8 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGO52424.1 - 8.3e-05 22.0 0.0 0.00056 19.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO52424.1 - 0.00011 22.9 0.0 0.00042 21.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGO52424.1 - 0.00024 20.2 0.0 0.00064 18.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGO52424.1 - 0.0006 19.8 0.1 0.023 14.6 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain Parvo_NS1 PF01057.12 EGO52424.1 - 0.00065 18.6 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 EGO52424.1 - 0.00072 19.7 0.0 0.0044 17.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGO52424.1 - 0.001 18.5 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EGO52424.1 - 0.0027 17.6 0.0 0.007 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EGO52424.1 - 0.0038 16.9 0.0 0.016 14.9 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 EGO52424.1 - 0.0087 14.8 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 EGO52424.1 - 0.011 15.8 0.0 0.032 14.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EGO52424.1 - 0.017 14.8 0.1 0.076 12.7 0.0 2.2 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGO52424.1 - 0.022 13.8 0.1 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EGO52424.1 - 0.031 13.5 0.0 0.072 12.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 EGO52424.1 - 0.033 13.3 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 EGO52424.1 - 0.05 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGO52424.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGO52424.1 - 0.075 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGO52424.1 - 0.083 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EGO52424.1 - 0.12 11.8 0.0 1.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain PPV_E1_C PF00519.12 EGO52424.1 - 0.31 9.6 0.0 0.48 8.9 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase NOA36 PF06524.7 EGO52424.1 - 0.98 8.6 3.1 1.7 7.8 2.2 1.2 1 0 0 1 1 1 0 NOA36 protein SH3BGR PF04908.10 EGO52425.1 - 2.8e-05 23.9 0.2 0.00022 21.0 0.0 2.3 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein DUF1675 PF07897.6 EGO52425.1 - 8.7 6.1 13.6 14 5.4 9.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Dynamitin PF04912.9 EGO52426.1 - 4.9e-31 107.9 7.7 2e-15 56.5 5.7 2.6 2 1 0 2 2 2 2 Dynamitin ThiS PF02597.15 EGO52426.1 - 4.9e-06 26.8 1.2 9.1e-05 22.8 0.0 3.7 4 1 0 4 4 2 1 ThiS family Spore_III_AB PF09548.5 EGO52426.1 - 0.0021 17.8 1.6 0.0088 15.8 0.2 2.2 2 0 0 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) FH2 PF02181.18 EGO52426.1 - 0.0058 15.5 3.6 0.16 10.8 0.0 2.7 3 0 0 3 3 3 1 Formin Homology 2 Domain HsbA PF12296.3 EGO52426.1 - 0.056 13.3 2.8 2.1 8.2 0.0 3.7 3 1 1 4 4 4 0 Hydrophobic surface binding protein A Snapin_Pallidin PF14712.1 EGO52426.1 - 0.11 12.8 5.1 22 5.4 0.0 4.3 3 1 2 5 5 5 0 Snapin/Pallidin Fmp27_WPPW PF10359.4 EGO52426.1 - 0.15 10.4 3.0 0.59 8.4 0.4 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF342 PF03961.8 EGO52426.1 - 0.16 10.3 5.4 6.4 5.0 2.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF342) Spectrin PF00435.16 EGO52426.1 - 0.26 11.5 10.0 0.65 10.3 2.0 3.3 3 0 0 3 3 3 0 Spectrin repeat FUSC PF04632.7 EGO52426.1 - 0.28 9.5 13.0 0.16 10.3 0.9 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF1192 PF06698.6 EGO52426.1 - 0.41 10.4 14.0 1.4 8.8 1.4 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) V_ATPase_I PF01496.14 EGO52426.1 - 0.42 8.4 3.6 0.56 8.0 0.2 2.3 2 1 1 3 3 3 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 EGO52426.1 - 0.42 10.4 18.3 0.29 11.0 5.4 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_int_SAM_2 PF12834.2 EGO52426.1 - 0.49 10.8 2.5 15 6.0 0.0 2.5 2 0 0 2 2 2 0 Phage integrase, N-terminal DUF948 PF06103.6 EGO52426.1 - 0.61 9.9 4.4 6.7 6.6 0.0 3.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.4 EGO52426.1 - 0.69 8.8 10.9 0.046 12.6 1.9 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Bap31 PF05529.7 EGO52426.1 - 0.74 9.2 9.7 1.8 8.0 3.1 2.7 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like ATP-synt_E PF05680.7 EGO52426.1 - 0.77 9.7 10.7 0.15 11.9 2.9 2.5 2 0 0 2 2 2 0 ATP synthase E chain AAA_13 PF13166.1 EGO52426.1 - 0.97 7.8 5.4 4.7 5.5 0.7 2.2 2 0 0 2 2 2 0 AAA domain Cwf_Cwc_15 PF04889.7 EGO52426.1 - 2 8.0 18.3 0.17 11.5 8.4 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CorA PF01544.13 EGO52426.1 - 2.6 6.9 6.3 6.7 5.6 2.7 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 EGO52426.1 - 2.7 7.7 5.2 1.9 8.2 0.5 2.6 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RmuC PF02646.11 EGO52426.1 - 3.1 6.5 8.8 0.83 8.4 0.5 2.8 3 0 0 3 3 3 0 RmuC family DUF3450 PF11932.3 EGO52426.1 - 3.9 6.6 12.6 0.14 11.3 0.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Mnd1 PF03962.10 EGO52426.1 - 5 6.7 14.2 2 8.0 3.6 3.0 3 0 0 3 3 3 0 Mnd1 family Phage_GP20 PF06810.6 EGO52426.1 - 6.4 6.1 13.8 0.53 9.7 3.2 3.0 3 1 0 3 3 3 0 Phage minor structural protein GP20 GrpE PF01025.14 EGO52426.1 - 8 5.9 12.5 5.9 6.4 3.9 3.0 3 0 0 3 3 3 0 GrpE RTC4 PF14474.1 EGO52427.1 - 6.1e-35 119.8 0.2 1.2e-34 118.9 0.2 1.5 1 0 0 1 1 1 1 RTC4-like domain PP2C PF00481.16 EGO52428.1 - 1.1e-62 211.7 0.0 2.3e-62 210.7 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EGO52428.1 - 3.8e-48 160.4 81.8 1.2e-07 31.1 0.1 13.7 6 4 8 15 15 15 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO52428.1 - 1.6e-36 123.8 74.3 1.6e-08 34.1 0.5 10.9 7 4 4 11 11 11 9 Leucine rich repeat Guanylate_cyc PF00211.15 EGO52428.1 - 1.6e-25 89.5 0.0 3.2e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EGO52428.1 - 7.5e-24 80.1 73.8 0.062 13.3 0.2 20.8 20 1 1 21 21 21 8 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 EGO52428.1 - 5.1e-22 76.9 2.0 5.1e-22 76.9 1.4 2.7 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain RA PF00788.18 EGO52428.1 - 4.3e-11 43.1 0.0 9.5e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 EGO52428.1 - 4.6e-07 28.9 69.2 0.54 10.6 0.1 18.5 18 2 2 20 20 20 2 Leucine rich repeat LRR_5 PF13306.1 EGO52428.1 - 0.011 15.4 1.2 0.07 12.8 0.0 2.5 1 1 0 2 2 2 0 Leucine rich repeats (6 copies) LRR_9 PF14580.1 EGO52428.1 - 0.091 12.3 20.3 0.14 11.6 2.3 4.6 2 1 2 4 4 4 0 Leucine-rich repeat Yos1 PF08571.5 EGO52429.1 - 2.7e-26 91.4 0.8 3e-26 91.3 0.6 1.0 1 0 0 1 1 1 1 Yos1-like UCH PF00443.24 EGO52430.1 - 7.3e-57 192.5 0.0 7.3e-57 192.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO52430.1 - 2.6e-27 96.0 0.4 3.1e-23 82.6 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase MIP-T3 PF10243.4 EGO52430.1 - 0.0017 16.9 21.5 0.0017 16.9 14.9 1.9 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Peptidase_C98 PF15499.1 EGO52430.1 - 0.028 13.7 1.8 0.17 11.1 0.3 2.5 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ycf1 PF05758.7 EGO52430.1 - 1.1 6.9 6.4 1.8 6.1 4.5 1.3 1 0 0 1 1 1 0 Ycf1 DUF4192 PF13830.1 EGO52430.1 - 2 8.0 9.1 3.5 7.1 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Sec61_beta PF03911.11 EGO52432.1 - 7.8e-21 73.6 1.5 9.9e-21 73.2 1.0 1.1 1 0 0 1 1 1 1 Sec61beta family DUF1180 PF06679.7 EGO52432.1 - 0.1 12.4 1.3 0.14 12.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) NIF PF03031.13 EGO52433.1 - 9.8e-52 174.8 0.3 1.4e-51 174.3 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hid1 PF12722.2 EGO52433.1 - 2.2 5.8 5.7 19 2.7 4.5 1.8 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein ABC_membrane_2 PF06472.10 EGO52435.1 - 9.2e-99 330.1 0.7 3.8e-98 328.0 0.0 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EGO52435.1 - 4.4e-16 59.4 0.0 1.1e-15 58.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 EGO52435.1 - 0.0038 17.5 0.2 0.017 15.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EGO52435.1 - 0.0038 17.2 0.0 0.032 14.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO52435.1 - 0.013 16.2 0.1 0.17 12.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGO52435.1 - 0.017 15.1 0.0 0.054 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EGO52435.1 - 0.038 13.5 0.0 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.21 EGO52435.1 - 0.048 13.1 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 EGO52435.1 - 0.081 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 EGO52435.1 - 0.093 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGO52435.1 - 0.12 11.4 0.0 0.29 10.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Aldo_ket_red PF00248.16 EGO52437.1 - 6.3e-49 166.3 0.0 7.2e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.2 EGO52438.1 - 2.3e-43 145.1 28.0 1.2e-12 47.1 0.6 6.2 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO52438.1 - 1.6e-29 101.4 58.3 4.1e-08 32.8 0.6 4.5 2 1 5 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 EGO52438.1 - 2.7e-11 41.8 28.3 0.33 11.1 0.6 10.0 9 2 0 9 9 9 4 Leucine Rich Repeat LRR_6 PF13516.1 EGO52438.1 - 3.2e-11 42.0 26.3 0.039 14.0 0.4 10.3 8 3 3 11 11 11 5 Leucine Rich repeat LRR_7 PF13504.1 EGO52438.1 - 3.8e-11 41.2 19.2 0.76 10.2 0.0 8.9 9 0 0 9 9 9 4 Leucine rich repeat LRR_9 PF14580.1 EGO52438.1 - 1.9e-10 40.6 10.0 0.0004 20.0 0.6 3.1 1 1 2 3 3 3 3 Leucine-rich repeat Abhydrolase_5 PF12695.2 EGO52439.1 - 6.8e-09 35.6 0.0 1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO52439.1 - 2.9e-07 30.6 0.0 8.4e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO52439.1 - 0.00035 19.8 0.0 0.00051 19.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2239 PF09998.4 EGO52440.1 - 0.13 11.8 1.7 0.13 11.8 0.3 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) BTB PF00651.26 EGO52441.1 - 2.6e-08 33.8 0.0 5.5e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 EGO52441.1 - 0.0001 22.3 0.0 0.0023 17.9 0.0 2.3 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Fer2_2 PF01799.15 EGO52441.1 - 0.061 13.2 0.1 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 [2Fe-2S] binding domain PCI PF01399.22 EGO52442.1 - 4.3e-10 39.8 0.0 3.8e-09 36.8 0.0 2.5 2 0 0 2 2 2 1 PCI domain DUF433 PF04255.9 EGO52442.1 - 0.032 13.6 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF433) TPR_11 PF13414.1 EGO52442.1 - 0.049 13.2 0.1 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 TPR repeat PriCT_1 PF08708.6 EGO52442.1 - 0.062 13.1 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) Ribosomal_L18ae PF01775.12 EGO52443.1 - 1.2e-59 199.6 0.2 1.5e-59 199.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Acetyltransf_3 PF13302.1 EGO52444.1 - 1.8e-35 122.1 0.0 2.9e-35 121.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGO52444.1 - 1.9e-06 27.9 0.0 0.01 15.8 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO52444.1 - 9.4e-05 22.3 0.0 0.011 15.6 0.0 2.2 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Propep_M14 PF02244.11 EGO52444.1 - 0.042 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Acetyltransf_1 PF00583.19 EGO52444.1 - 0.084 12.9 0.0 5.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family ADK_lid PF05191.9 EGO52446.1 - 0.084 12.5 0.7 0.17 11.5 0.1 1.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid DUF1656 PF07869.7 EGO52447.1 - 0.064 13.0 1.8 0.12 12.1 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) ATP-synt_E PF05680.7 EGO52448.1 - 8.4e-30 102.5 0.9 9.4e-30 102.4 0.6 1.0 1 0 0 1 1 1 1 ATP synthase E chain DUF349 PF03993.7 EGO52448.1 - 0.0083 16.2 0.3 0.012 15.7 0.2 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF349) BPL_N PF09825.4 EGO52448.1 - 0.0099 14.6 0.1 0.0099 14.6 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal WD40 PF00400.27 EGO52449.1 - 1.3e-18 66.1 10.7 8.6e-07 28.6 0.0 6.7 8 1 0 8 8 8 4 WD domain, G-beta repeat Aldo_ket_red PF00248.16 EGO52450.1 - 2.7e-59 200.3 0.0 3e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2187 PF09953.4 EGO52450.1 - 0.093 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) CAP_GLY PF01302.20 EGO52452.1 - 1.8e-17 62.7 0.0 3.3e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EGO52452.1 - 7.2e-16 57.4 9.3 0.0024 17.4 0.0 5.5 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO52452.1 - 4.5e-09 35.9 8.3 0.00032 20.4 0.1 4.9 2 1 3 6 6 6 4 Leucine rich repeat LRR_6 PF13516.1 EGO52452.1 - 3e-08 32.9 8.3 1.5 9.1 0.0 7.1 7 1 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.28 EGO52452.1 - 4.8e-06 25.8 11.2 2 8.7 0.0 7.6 6 2 0 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 EGO52452.1 - 0.014 15.4 6.5 1.7e+02 3.1 0.0 6.8 7 0 0 7 7 7 0 Leucine rich repeat LRR_9 PF14580.1 EGO52452.1 - 0.1 12.1 0.1 1.9 8.0 0.0 2.7 2 1 1 3 3 3 0 Leucine-rich repeat EF-1_beta_acid PF10587.4 EGO52452.1 - 1.7 8.8 6.0 3.7 7.7 4.1 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region MaoC_dehydratas PF01575.14 EGO52453.1 - 3.4e-21 74.8 0.0 6.1e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EGO52453.1 - 2.2e-08 33.9 0.0 1.4e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Calici_MSP PF05752.6 EGO52454.1 - 3.8 7.0 6.7 0.91 9.1 0.2 2.8 3 0 0 3 3 3 0 Calicivirus minor structural protein PI-PLC-X PF00388.14 EGO52456.1 - 1.5e-09 37.3 0.0 2.5e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain GPI-anchored PF10342.4 EGO52458.1 - 9.8e-21 74.0 0.0 9.8e-21 74.0 0.0 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Tubulin PF00091.20 EGO52459.1 - 6.2e-66 222.3 0.0 8.2e-66 221.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGO52459.1 - 1.9e-41 141.0 0.0 2.9e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EGO52459.1 - 0.0018 17.7 0.0 0.0037 16.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.17 EGO52460.1 - 1.3e-12 47.1 0.2 6.2e-09 35.3 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO52460.1 - 4.9e-11 42.3 0.0 0.0002 21.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO52460.1 - 2.8e-10 40.0 0.0 1.3e-06 28.2 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.6 EGO52461.1 - 1.9e-29 102.6 6.3 1.9e-29 102.6 4.4 3.8 2 2 0 3 3 3 1 Sds3-like Coiled-coil_56 PF09813.4 EGO52462.1 - 0.00034 20.5 0.0 0.00035 20.5 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.3 EGO52463.1 - 2.4e-61 207.1 0.0 3.7e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) ABC_membrane PF00664.18 EGO52466.1 - 7.1e-05 22.3 2.9 0.018 14.4 0.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region UVR PF02151.14 EGO52468.1 - 0.12 11.9 0.5 1.1 8.8 0.1 2.5 2 0 0 2 2 2 0 UvrB/uvrC motif Pkinase PF00069.20 EGO52469.1 - 1e-71 241.1 0.0 1.4e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO52469.1 - 6.7e-34 117.1 0.0 1e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO52469.1 - 0.00041 19.4 0.0 0.00066 18.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EGO52469.1 - 0.001 18.4 0.0 0.0025 17.1 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EGO52469.1 - 0.0076 15.3 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.21 EGO52470.1 - 1.8e-25 88.9 0.0 2.2e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO52470.1 - 4.3e-07 29.7 0.0 4.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EGO52470.1 - 0.0028 17.3 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EGO52470.1 - 0.004 17.0 0.1 0.0092 15.8 0.0 1.7 1 1 1 2 2 2 1 RWD domain Sec1 PF00995.18 EGO52471.1 - 9.7e-138 460.2 0.0 1.1e-137 460.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Amino_oxidase PF01593.19 EGO52472.1 - 8.5e-86 288.7 0.0 1.3e-85 288.1 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EGO52472.1 - 5.9e-10 39.1 0.0 1.7e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain HMG_box_2 PF09011.5 EGO52472.1 - 1.8e-06 28.2 2.8 1.8e-06 28.2 1.9 2.3 1 1 1 2 2 2 1 HMG-box domain NAD_binding_8 PF13450.1 EGO52472.1 - 2.7e-06 27.3 0.0 7.3e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EGO52472.1 - 3.5e-06 27.1 3.5 3.5e-06 27.1 2.4 2.7 1 1 1 2 2 2 1 HMG (high mobility group) box ATP-synt PF00231.14 EGO52473.1 - 8.5e-72 241.9 2.5 9.9e-72 241.7 1.7 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I_N PF02919.10 EGO52474.1 - 4.6e-92 307.1 3.4 4.6e-92 307.1 2.3 2.9 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EGO52474.1 - 1e-84 283.3 8.6 3e-84 281.7 6.0 1.8 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EGO52474.1 - 9.1e-30 102.1 0.1 9.1e-30 102.1 0.1 2.3 2 0 0 2 2 2 1 C-terminal topoisomerase domain Glyco_hydro_16 PF00722.16 EGO52475.1 - 4e-44 150.1 1.1 8e-44 149.1 0.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 p450 PF00067.17 EGO52476.1 - 1.5e-63 214.9 0.0 2e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_20 PF00728.17 EGO52477.1 - 1.7e-81 274.1 0.0 2.1e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EGO52477.1 - 2.1e-23 83.3 0.0 6e-23 81.9 0.0 1.8 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EGO52477.1 - 5.2e-07 30.2 0.2 0.00052 20.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, domain 2 NAD_binding_8 PF13450.1 EGO52478.1 - 7.4e-09 35.5 0.1 2.7e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain zf-CCCH_2 PF14608.1 EGO52478.1 - 2.9e-06 27.0 12.2 2.9e-06 27.0 8.4 5.7 5 0 0 5 5 5 2 Zinc finger C-x8-C-x5-C-x3-H type Amino_oxidase PF01593.19 EGO52478.1 - 1.4e-05 24.3 0.0 0.052 12.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 EGO52478.1 - 0.00026 19.9 0.0 0.019 13.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGO52478.1 - 0.024 15.0 0.1 3.5 8.1 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Nab2 PF11517.3 EGO52478.1 - 0.067 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Med14 PF08638.6 EGO52479.1 - 6.2e-58 195.2 0.7 1.3e-34 119.1 0.0 2.9 2 1 1 3 3 3 2 Mediator complex subunit MED14 PAT1 PF09770.4 EGO52479.1 - 2.6 6.1 65.9 3.9 5.5 45.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 EGO52479.1 - 4.1 5.4 81.4 6 4.9 56.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal G6PD_C PF02781.11 EGO52480.1 - 4.2e-135 449.2 0.0 6.2e-135 448.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EGO52480.1 - 3.5e-65 219.6 0.0 5.8e-65 218.9 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.3 EGO52480.1 - 0.11 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) Ribosomal_L35Ae PF01247.13 EGO52481.1 - 2.7e-42 142.4 0.5 3.1e-42 142.2 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EGO52481.1 - 0.00044 20.1 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain VMA21 PF09446.5 EGO52483.1 - 5.4e-15 55.0 8.2 7.5e-15 54.6 5.7 1.2 1 0 0 1 1 1 1 VMA21-like domain MARVEL PF01284.18 EGO52483.1 - 0.062 13.1 1.1 0.08 12.7 0.8 1.1 1 0 0 1 1 1 0 Membrane-associating domain Transposase_28 PF04195.7 EGO52483.1 - 0.1 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative gypsy type transposon DUF1118 PF06549.7 EGO52483.1 - 0.12 12.5 0.5 0.16 12.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) DUF2721 PF11026.3 EGO52483.1 - 0.65 9.6 3.1 0.9 9.1 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) SNF2_N PF00176.18 EGO52484.1 - 4.8e-57 193.0 0.0 9e-57 192.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO52484.1 - 4.1e-14 52.1 0.0 1.3e-13 50.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3336 PF11815.3 EGO52485.1 - 3.5e-37 127.1 0.1 1.1e-36 125.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EGO52485.1 - 5e-14 52.6 0.4 1.4e-13 51.2 0.3 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase UME PF08064.8 EGO52485.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 UME (NUC010) domain Lipase_GDSL_2 PF13472.1 EGO52488.1 - 6.8e-17 62.1 0.4 1.1e-16 61.5 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGO52488.1 - 3.4e-14 53.2 0.1 1.1e-13 51.5 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BOP1NT PF08145.7 EGO52489.1 - 3.6e-103 344.8 7.0 5.7e-103 344.1 4.8 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EGO52489.1 - 1.3e-27 94.5 5.4 8e-10 38.2 0.0 7.3 7 1 0 7 7 7 4 WD domain, G-beta repeat Zn_clus PF00172.13 EGO52490.1 - 7.3e-06 25.7 10.1 1.4e-05 24.8 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SURF4 PF02077.10 EGO52491.1 - 9.4e-97 323.5 7.9 1.1e-96 323.3 5.5 1.0 1 0 0 1 1 1 1 SURF4 family Halogen_Hydrol PF10112.4 EGO52491.1 - 0.65 9.3 3.1 4.4 6.6 0.4 2.3 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Peptidase_A24 PF01478.13 EGO52491.1 - 0.84 9.8 14.8 0.22 11.7 0.7 2.7 2 1 0 2 2 2 0 Type IV leader peptidase family Wzy_C PF04932.10 EGO52491.1 - 3.3 7.4 11.0 0.23 11.2 2.8 2.2 2 0 0 2 2 2 0 O-Antigen ligase VSP PF03302.8 EGO52492.1 - 0.00037 19.2 1.1 0.00061 18.5 0.8 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Shisa PF13908.1 EGO52492.1 - 0.22 11.7 4.9 0.82 9.8 3.2 2.2 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator MtrF PF09472.5 EGO52492.1 - 0.53 9.5 2.6 1.1 8.5 1.8 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Alg6_Alg8 PF03155.10 EGO52493.1 - 9.8e-129 430.2 24.7 5.5e-80 269.4 6.5 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family BRO1 PF03097.13 EGO52494.1 - 2.6e-05 23.1 0.0 7.1e-05 21.7 0.0 1.6 2 0 0 2 2 2 1 BRO1-like domain Leo1 PF04004.8 EGO52495.1 - 4.4e-29 101.3 0.1 4.4e-29 101.3 0.0 1.8 2 0 0 2 2 2 1 Leo1-like protein Stn1_C PF12659.2 EGO52495.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH Mob1_phocein PF03637.12 EGO52496.1 - 9.1e-37 126.4 0.1 1.4e-17 63.8 0.1 2.1 2 0 0 2 2 2 2 Mob1/phocein family OSTMP1 PF09777.4 EGO52496.1 - 0.027 13.6 0.2 0.042 13.0 0.1 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor CorA PF01544.13 EGO52497.1 - 9.4e-41 139.7 1.1 1.3e-39 136.0 0.8 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CSTF2_hinge PF14327.1 EGO52498.1 - 1.2e-30 105.4 1.1 2.1e-30 104.6 0.7 1.4 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EGO52498.1 - 1.3e-22 79.2 0.0 2.2e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO52498.1 - 7.7e-19 67.4 0.0 1.9e-18 66.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO52498.1 - 1.4e-06 28.0 0.0 2.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EGO52498.1 - 0.00075 18.7 4.4 0.00075 18.7 3.1 2.5 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal Band_7 PF01145.20 EGO52499.1 - 9.6e-25 87.5 1.8 1.4e-24 86.9 1.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family E_Pc_C PF06752.7 EGO52499.1 - 0.057 12.9 1.0 0.11 12.0 0.7 1.4 1 1 0 1 1 1 0 Enhancer of Polycomb C-terminus Methyltransf_5 PF01795.14 EGO52499.1 - 0.1 11.8 4.1 0.16 11.2 2.9 1.3 1 1 0 1 1 1 0 MraW methylase family ubiquitin PF00240.18 EGO52500.1 - 1.3e-25 88.6 0.1 1.4e-25 88.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGO52500.1 - 2.6e-18 65.4 0.3 2.9e-18 65.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGO52500.1 - 0.00013 22.1 0.0 0.0004 20.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain CTDII PF01556.13 EGO52500.1 - 0.027 14.3 0.4 0.038 13.9 0.3 1.3 1 0 0 1 1 1 0 DnaJ C terminal domain Rad60-SLD_2 PF13881.1 EGO52500.1 - 0.045 13.6 0.1 0.13 12.1 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Elongin_A PF06881.6 EGO52501.1 - 3.9e-13 49.7 0.5 8.6e-13 48.6 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A CEP44 PF15007.1 EGO52501.1 - 0.054 13.1 0.0 0.19 11.4 0.0 1.8 1 1 1 2 2 2 0 Centrosomal spindle body, CEP44 THOC7 PF05615.8 EGO52502.1 - 5e-47 159.6 5.2 5e-47 159.6 3.6 1.6 2 0 0 2 2 2 1 Tho complex subunit 7 Med9 PF07544.8 EGO52502.1 - 0.014 15.1 3.3 0.11 12.2 2.3 2.4 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 AAA_23 PF13476.1 EGO52502.1 - 0.55 10.5 3.6 1.3 9.3 2.5 1.6 1 0 0 1 1 1 0 AAA domain RTBV_P46 PF06216.6 EGO52502.1 - 3.5 6.3 8.2 0.52 9.0 1.0 2.0 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein Mnd1 PF03962.10 EGO52502.1 - 6.5 6.3 11.3 3.2 7.3 1.4 2.5 1 1 1 2 2 2 0 Mnd1 family E1-E2_ATPase PF00122.15 EGO52503.1 - 2.6e-64 216.3 8.5 5.7e-64 215.2 5.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGO52503.1 - 1.9e-45 154.6 5.6 1.9e-45 154.6 3.9 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGO52503.1 - 1.7e-33 116.8 0.0 5.5e-33 115.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO52503.1 - 5.8e-22 77.4 0.0 1.1e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EGO52503.1 - 3e-21 74.6 0.0 7.6e-21 73.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGO52503.1 - 9.2e-17 61.8 0.8 2.7e-16 60.3 0.2 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGO52503.1 - 2.2e-08 34.0 2.2 6.6e-06 25.8 0.6 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGO52503.1 - 0.0068 16.6 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase TUG-UBL1 PF11470.3 EGO52504.1 - 4.7e-28 96.9 0.1 6.1e-27 93.3 0.0 2.5 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 EGO52504.1 - 0.0029 17.6 0.0 0.024 14.6 0.0 2.4 3 0 0 3 3 3 1 UBX domain RA PF00788.18 EGO52504.1 - 0.031 14.7 0.1 0.086 13.3 0.0 1.7 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain RBD PF02196.10 EGO52504.1 - 0.06 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain Ribosomal_L36e PF01158.13 EGO52505.1 - 2e-40 136.7 7.0 2.2e-40 136.5 4.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e AstB PF04996.7 EGO52505.1 - 0.075 11.8 0.1 0.09 11.5 0.1 1.1 1 0 0 1 1 1 0 Succinylarginine dihydrolase LemA PF04011.7 EGO52505.1 - 0.11 11.5 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 LemA family Lipase_3 PF01764.20 EGO52508.1 - 2.1e-30 105.1 0.0 3.2e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EGO52508.1 - 0.00011 22.1 0.9 0.00016 21.6 0.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO52508.1 - 0.00014 21.5 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EGO52508.1 - 0.0024 17.3 0.1 0.044 13.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Thioesterase PF00975.15 EGO52508.1 - 0.0037 17.5 0.0 0.006 16.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 EGO52508.1 - 0.0059 16.0 0.0 0.0091 15.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 EGO52508.1 - 0.0078 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EGO52508.1 - 0.024 14.2 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Glyco_trans_1_4 PF13692.1 EGO52508.1 - 0.078 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 14-3-3 PF00244.15 EGO52509.1 - 1.3e-114 381.2 1.3 1.3e-114 381.2 0.9 1.3 2 0 0 2 2 2 1 14-3-3 protein DUF837 PF05769.6 EGO52509.1 - 0.017 14.6 0.4 6 6.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) TPR_12 PF13424.1 EGO52509.1 - 0.023 14.6 1.2 3.2 7.7 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_60s PF00428.14 EGO52509.1 - 0.69 10.3 12.6 0.33 11.3 4.7 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Syja_N PF02383.13 EGO52512.1 - 6.4e-73 245.3 0.0 1e-72 244.6 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Suf PF05843.9 EGO52513.1 - 2.3e-05 24.2 1.0 0.01 15.6 0.0 3.2 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EGO52513.1 - 4.9e-05 23.6 3.9 1.6 9.5 0.0 6.2 5 3 2 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO52513.1 - 0.00082 19.9 4.9 0.0031 18.1 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat peroxidase PF00141.18 EGO52514.1 - 1.4e-49 168.6 0.0 2.2e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase ATP11 PF06644.6 EGO52515.1 - 7.6e-95 317.4 0.0 8.9e-95 317.1 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Glyphos_transf PF04464.9 EGO52515.1 - 0.046 12.4 0.0 0.079 11.7 0.0 1.3 1 0 0 1 1 1 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Z1 PF10593.4 EGO52515.1 - 0.12 11.5 0.1 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Z1 domain AMP-binding PF00501.23 EGO52516.1 - 4.2e-86 288.9 0.0 4.9e-86 288.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO52516.1 - 1.5e-13 51.4 0.2 4.2e-13 50.0 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Phosphoprotein PF00922.12 EGO52518.1 - 6.4 5.9 9.4 7.3 5.7 6.5 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein COG4 PF08318.7 EGO52519.1 - 9.4e-67 225.1 0.0 1.4e-54 185.1 0.0 2.3 1 1 1 2 2 2 2 COG4 transport protein E1-E2_ATPase PF00122.15 EGO52520.1 - 2.6e-72 242.6 0.6 4.3e-72 241.8 0.4 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGO52520.1 - 1.2e-45 155.3 1.4 2.3e-45 154.3 1.0 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGO52520.1 - 1e-29 104.4 0.0 2.3e-28 100.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGO52520.1 - 2.3e-20 71.7 0.0 5.1e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGO52520.1 - 2.1e-14 54.1 0.2 6e-14 52.6 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO52520.1 - 3.3e-12 46.2 0.0 6.2e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGO52520.1 - 2.9e-05 23.7 0.7 2.9e-05 23.7 0.5 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 EGO52521.1 - 3.3e-35 120.3 0.0 6.4e-35 119.4 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EGO52521.1 - 2.2e-09 36.3 0.2 1.7e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EGO52521.1 - 0.0011 18.6 0.0 0.026 14.1 0.0 2.4 2 0 0 2 2 2 1 ScpA/B protein Peptidase_S9 PF00326.16 EGO52522.1 - 5.6e-54 182.6 0.0 9.6e-54 181.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO52522.1 - 2e-10 40.5 0.0 3.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO52522.1 - 8.6e-07 29.0 0.0 2.4e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EGO52522.1 - 5.2e-05 21.8 0.0 0.0041 15.6 0.0 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) PD40 PF07676.7 EGO52522.1 - 0.02 14.5 0.1 9.2 6.0 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat NuA4 PF09340.5 EGO52524.1 - 6.5e-28 96.2 0.9 6.5e-28 96.2 0.6 1.5 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Pheromone PF08015.6 EGO52527.1 - 0.00057 20.6 3.9 0.0077 17.0 0.5 2.9 2 0 0 2 2 2 1 Fungal mating-type pheromone DUF3482 PF11981.3 EGO52527.1 - 7.7 5.6 12.2 3.4 6.7 3.6 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3482) PWI PF01480.12 EGO52529.1 - 9.6e-30 102.5 0.1 1.6e-29 101.8 0.1 1.4 1 0 0 1 1 1 1 PWI domain FAA_hydrolase PF01557.13 EGO52531.1 - 3.3e-52 177.1 0.0 4e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Ctr PF04145.10 EGO52532.1 - 2.5e-39 134.6 1.0 3e-39 134.3 0.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF2946 PF11162.3 EGO52532.1 - 0.016 15.3 0.2 0.034 14.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) PHO4 PF01384.15 EGO52532.1 - 0.2 10.3 2.5 0.4 9.2 1.6 1.6 1 1 0 1 1 1 0 Phosphate transporter family NUDIX PF00293.23 EGO52533.1 - 1.2e-13 50.8 0.2 8e-13 48.1 0.0 2.1 1 1 1 2 2 2 1 NUDIX domain EXS PF03124.9 EGO52535.1 - 2.3e-102 342.5 5.8 2.6e-102 342.3 4.0 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.9 EGO52537.1 - 1.9e-50 171.4 0.3 2.5e-50 171.0 0.2 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EGO52537.1 - 3.3e-12 46.0 8.3 5.6e-12 45.2 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO52537.1 - 5.1e-12 45.6 7.7 8.2e-12 44.9 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO52537.1 - 2.7e-10 39.7 6.3 4.1e-10 39.1 4.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO52537.1 - 4.6e-10 38.9 6.4 7.9e-10 38.2 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO52537.1 - 2.2e-08 33.6 5.2 3.4e-08 33.0 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGO52537.1 - 5.4e-07 29.3 7.7 9e-07 28.6 5.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGO52537.1 - 8.6e-05 22.5 7.1 0.00023 21.2 4.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EGO52537.1 - 0.00038 20.1 2.7 0.00068 19.3 1.9 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EGO52537.1 - 0.00051 19.7 4.2 0.001 18.7 2.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EGO52537.1 - 0.0051 16.3 0.8 0.0094 15.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EGO52537.1 - 0.03 13.9 6.9 0.066 12.8 4.8 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGO52537.1 - 0.033 14.0 2.9 0.077 12.8 2.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Cyt_c_ox_IV PF12270.3 EGO52537.1 - 0.051 13.3 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV TerY-C PF15616.1 EGO52537.1 - 0.22 11.4 2.6 0.42 10.5 1.8 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain IBR PF01485.16 EGO52537.1 - 1.4 8.7 7.8 13 5.7 5.7 2.1 1 1 1 2 2 2 0 IBR domain Abhydrolase_5 PF12695.2 EGO52538.1 - 2.6e-21 75.8 0.0 3.5e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO52538.1 - 3.1e-18 66.4 0.0 6.9e-17 62.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO52538.1 - 4.2e-07 29.7 0.2 0.0064 16.0 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 EGO52538.1 - 4.5e-05 22.0 0.1 2 6.8 0.0 3.0 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) DUF818 PF05677.7 EGO52538.1 - 5.8e-05 21.9 0.0 9.1e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.8 EGO52538.1 - 0.0018 17.7 0.0 0.0059 16.0 0.0 1.8 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DUF1057 PF06342.7 EGO52538.1 - 0.0019 17.0 0.1 0.0025 16.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S9 PF00326.16 EGO52538.1 - 0.0058 15.8 0.0 0.1 11.8 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EGO52538.1 - 0.0082 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EGO52538.1 - 0.018 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 EGO52538.1 - 0.028 13.7 0.0 2 7.6 0.0 2.7 2 1 0 2 2 2 0 Dienelactone hydrolase family PGAP1 PF07819.8 EGO52538.1 - 0.046 13.3 0.3 0.2 11.1 0.2 2.0 1 1 0 1 1 1 0 PGAP1-like protein DUF1749 PF08538.5 EGO52538.1 - 0.047 12.5 0.1 2.3 7.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) Abhydrolase_2 PF02230.11 EGO52538.1 - 0.047 13.1 0.2 1.4 8.3 0.0 2.5 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 EGO52538.1 - 0.081 12.3 0.0 0.49 9.7 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EGO52538.1 - 0.15 11.4 0.0 0.34 10.2 0.0 1.5 2 0 0 2 2 2 0 Putative esterase zf-LYAR PF08790.6 EGO52540.1 - 6.7e-15 54.4 5.0 1.5e-14 53.3 3.5 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger R3H PF01424.17 EGO52541.1 - 2.8e-14 52.5 0.1 7.1e-14 51.2 0.0 1.7 1 0 0 1 1 1 1 R3H domain PTPA PF03095.10 EGO52543.1 - 1.4e-110 369.1 0.0 1.7e-110 368.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RNase_PH PF01138.16 EGO52544.1 - 4.9e-14 52.7 0.1 8.5e-14 51.9 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_kinase PF01513.16 EGO52546.1 - 9.7e-72 241.1 0.0 1.2e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Homeobox PF00046.24 EGO52547.1 - 6.7e-15 54.4 2.1 1.5e-14 53.2 1.4 1.7 1 0 0 1 1 1 1 Homeobox domain zf-GRF PF06839.7 EGO52548.1 - 7.5e-12 44.9 0.5 2.2e-11 43.4 0.3 1.8 1 0 0 1 1 1 1 GRF zinc finger BMF PF15185.1 EGO52548.1 - 0.018 14.3 3.5 0.017 14.4 1.5 1.6 1 1 0 1 1 1 0 Bcl-2-modifying factor, apoptosis DUF605 PF04652.11 EGO52548.1 - 1.3 8.3 14.9 1.6 8.0 10.4 1.1 1 0 0 1 1 1 0 Vta1 like ELMO_CED12 PF04727.8 EGO52549.1 - 3.3e-53 179.7 0.0 5.9e-53 178.9 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 EGO52549.1 - 0.0011 18.7 0.2 0.063 12.9 0.0 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3361) C2 PF00168.25 EGO52550.1 - 2e-72 239.0 1.9 2.5e-21 75.2 0.1 5.5 5 0 0 5 5 5 5 C2 domain NT-C2 PF10358.4 EGO52550.1 - 0.0036 16.8 0.3 0.03 13.8 0.0 2.5 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins FKBP_C PF00254.23 EGO52550.1 - 0.03 14.3 0.0 0.17 11.9 0.0 2.3 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2404 PF10296.4 EGO52550.1 - 0.049 13.7 0.1 0.26 11.4 0.0 2.3 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) zf-CCCH PF00642.19 EGO52551.1 - 7e-09 35.1 17.3 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EGO52551.1 - 0.00068 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO52551.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SCRG1 PF15224.1 EGO52551.1 - 0.63 9.8 5.1 0.49 10.2 0.2 2.4 2 0 0 2 2 2 0 Scrapie-responsive protein 1 Oxysterol_BP PF01237.13 EGO52553.1 - 4.8e-85 285.1 0.0 6.3e-85 284.7 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Ammonium_transp PF00909.16 EGO52554.1 - 6.7e-115 383.7 28.6 7.7e-115 383.5 19.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family His_Phos_2 PF00328.17 EGO52555.1 - 7.8e-44 150.4 0.0 9.3e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CRT10 PF08728.5 EGO52556.1 - 7.5e-21 73.8 0.0 2.7e-13 48.8 0.0 2.1 2 0 0 2 2 2 2 CRT10 Cellulase PF00150.13 EGO52557.1 - 1.1e-39 136.3 0.0 1.3e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MutL PF13941.1 EGO52557.1 - 0.061 11.6 0.0 0.09 11.0 0.0 1.1 1 0 0 1 1 1 0 MutL protein 7tm_2 PF00002.19 EGO52558.1 - 3.9e-06 26.1 9.1 6e-06 25.5 6.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EGO52558.1 - 0.0029 16.5 3.4 0.0029 16.5 2.4 1.7 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor DC_STAMP PF07782.8 EGO52558.1 - 0.092 12.3 1.1 0.69 9.5 0.2 2.3 1 1 1 2 2 2 0 DC-STAMP-like protein Vma12 PF11712.3 EGO52558.1 - 0.78 9.4 2.4 5.6 6.6 0.2 2.8 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pkinase PF00069.20 EGO52560.1 - 2.5e-08 33.3 0.0 5.4e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO52560.1 - 4.2e-06 26.0 0.0 6e-05 22.2 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Zn_clus PF00172.13 EGO52563.1 - 0.0015 18.4 5.2 0.0029 17.4 3.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 EGO52564.1 - 1.1e-20 74.3 0.1 1.5e-20 73.9 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EGO52564.1 - 0.027 13.3 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 CsiD DSPn PF14671.1 EGO52565.1 - 2.1e-43 147.7 0.0 6e-40 136.5 0.0 3.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EGO52565.1 - 4.1e-17 62.0 0.0 8.2e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGO52565.1 - 2.2e-06 27.1 0.0 4.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGO52565.1 - 0.00036 20.6 0.0 0.00083 19.4 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EGO52565.1 - 0.12 12.6 0.1 0.3 11.3 0.1 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.7 EGO52565.1 - 0.19 11.1 0.1 0.36 10.2 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Ecl1 PF12855.2 EGO52566.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Life-span regulatory factor Pcc1 PF09341.5 EGO52567.1 - 1.4e-27 95.5 0.4 1.6e-27 95.2 0.3 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 WD40 PF00400.27 EGO52568.1 - 2.9e-58 191.8 23.9 3.2e-12 45.8 0.1 8.2 8 1 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 EGO52568.1 - 3.4e-07 30.1 0.1 0.0017 18.1 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGO52568.1 - 1e-06 27.2 10.6 0.012 13.7 0.3 5.2 2 2 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGO52568.1 - 0.0002 20.2 2.3 0.12 11.1 0.6 3.7 2 2 2 4 4 4 2 Nup133 N terminal like BBS2_Mid PF14783.1 EGO52568.1 - 0.0038 17.0 0.0 0.66 9.7 0.0 3.2 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region DUF3312 PF11768.3 EGO52568.1 - 0.047 11.9 0.0 0.3 9.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) DUF1777 PF08648.7 EGO52568.1 - 9.8 5.8 64.0 0.85 9.3 32.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) Exo_endo_phos PF03372.18 EGO52569.1 - 7.9e-15 55.4 0.0 1.2e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 EGO52570.1 - 5.5e-22 78.1 0.2 3.9e-16 58.9 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO52570.1 - 3.1e-06 26.4 0.1 2.2e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGO52570.1 - 0.0044 16.7 0.1 0.011 15.4 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGO52570.1 - 0.025 13.5 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FKBP_C PF00254.23 EGO52571.1 - 2.3e-32 110.8 0.0 6.9e-31 106.1 0.0 2.8 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glyco_trans_2_3 PF13632.1 EGO52572.1 - 6.5e-18 65.1 0.4 1.1e-17 64.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 FimP PF09766.4 EGO52574.1 - 3.7e-28 98.6 11.0 4.7e-28 98.2 7.6 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF3540 PF12059.3 EGO52574.1 - 0.0099 15.5 0.2 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3540) DUF632 PF04782.7 EGO52574.1 - 0.028 13.5 1.6 0.029 13.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF632) TSC22 PF01166.13 EGO52574.1 - 0.057 13.3 0.1 0.057 13.3 0.1 2.8 3 0 0 3 3 3 0 TSC-22/dip/bun family Flagellin_N PF00669.15 EGO52574.1 - 0.13 12.1 3.3 1.1 9.0 0.4 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF4200 PF13863.1 EGO52574.1 - 0.24 11.3 16.5 0.3 11.0 1.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.4 EGO52574.1 - 0.44 10.4 11.9 0.46 10.3 2.2 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PP28 PF10252.4 EGO52574.1 - 1.9 8.5 10.1 0.31 11.0 2.6 2.4 2 1 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Cortex-I_coil PF09304.5 EGO52574.1 - 3.2 7.8 13.1 1 9.4 3.3 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil Pinin_SDK_memA PF04696.8 EGO52574.1 - 5.6 6.5 11.4 0.4 10.2 3.8 2.0 2 1 0 2 2 2 0 pinin/SDK/memA/ protein conserved region ADIP PF11559.3 EGO52574.1 - 8.4 6.2 15.2 3.3 7.5 2.8 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HlyIII PF03006.15 EGO52575.1 - 8.2e-58 195.4 23.4 9.9e-58 195.1 16.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF1771 PF08590.5 EGO52575.1 - 0.023 14.7 2.0 0.073 13.0 1.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) SPC12 PF06645.8 EGO52575.1 - 7 6.5 6.5 0.48 10.2 0.7 1.9 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) RabGAP-TBC PF00566.13 EGO52576.1 - 1.4e-32 112.9 2.0 5.9e-27 94.5 0.0 2.6 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Sulfate_transp PF00916.15 EGO52577.1 - 6.1e-71 238.6 8.6 9.6e-71 238.0 5.9 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGO52577.1 - 1.1e-30 105.0 2.2 1.1e-30 105.0 1.5 3.2 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGO52577.1 - 3.4e-08 32.9 0.0 6.3e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 EGO52577.1 - 0.023 14.3 1.2 0.023 14.3 0.8 3.0 2 0 0 2 2 2 0 Stannin transmembrane DUF2207 PF09972.4 EGO52577.1 - 0.2 10.2 1.3 0.28 9.7 0.1 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) zf-UBR PF02207.15 EGO52578.1 - 4.6e-18 64.7 16.5 1e-17 63.5 11.5 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EGO52578.1 - 1.2e-05 24.8 0.0 3.4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS UCR_UQCRX_QCR9 PF05365.7 EGO52579.1 - 8.4e-29 98.9 1.9 9.2e-29 98.8 1.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.5 EGO52580.1 - 4.5e-14 51.6 3.1 8.3e-14 50.8 2.2 1.5 1 0 0 1 1 1 1 Mago binding DUF2201_N PF13203.1 EGO52580.1 - 3.4 6.7 8.7 4.5 6.3 6.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.7 EGO52580.1 - 6.5 6.5 11.9 8.3 6.2 8.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BCS1_N PF08740.6 EGO52581.1 - 3.1e-47 160.6 0.0 4.4e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGO52581.1 - 2.6e-20 72.9 0.0 4.1e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGO52581.1 - 3.4e-05 24.6 0.0 9.3e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGO52581.1 - 0.00021 21.0 0.0 0.00053 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EGO52581.1 - 0.00035 19.6 0.0 0.00061 18.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EGO52581.1 - 0.00036 19.9 0.0 0.00081 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGO52581.1 - 0.00041 20.4 0.0 0.00093 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO52581.1 - 0.001 19.0 0.0 0.0023 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGO52581.1 - 0.0017 18.0 0.1 0.023 14.4 0.1 2.6 1 1 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 EGO52581.1 - 0.002 17.0 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EGO52581.1 - 0.0023 17.8 0.0 0.0094 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EGO52581.1 - 0.0046 16.5 0.6 0.028 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EGO52581.1 - 0.0067 16.0 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EGO52581.1 - 0.012 14.7 0.1 0.12 11.5 0.0 2.2 2 1 1 3 3 3 0 KaiC AAA_18 PF13238.1 EGO52581.1 - 0.015 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGO52581.1 - 0.027 14.6 0.1 0.073 13.2 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_28 PF13521.1 EGO52581.1 - 0.027 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGO52581.1 - 0.035 14.3 0.0 0.083 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.1 EGO52581.1 - 0.043 13.7 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EGO52581.1 - 0.053 14.0 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Zeta_toxin PF06414.7 EGO52581.1 - 0.06 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Rad17 PF03215.10 EGO52581.1 - 0.072 11.7 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EGO52581.1 - 0.072 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EGO52581.1 - 0.084 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 EGO52581.1 - 0.089 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EGO52581.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase TIP49 PF06068.8 EGO52581.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus DUF258 PF03193.11 EGO52581.1 - 0.19 10.9 0.0 0.37 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ribosomal_S11 PF00411.14 EGO52582.1 - 1.2e-10 41.5 0.1 2e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.10 EGO52583.1 - 7.3e-35 120.1 0.0 1.7e-34 118.9 0.0 1.6 1 0 0 1 1 1 1 Tim44-like domain ABC_tran PF00005.22 EGO52584.1 - 2e-31 109.1 0.0 3.6e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EGO52584.1 - 3.4e-12 46.3 8.0 3.4e-12 46.3 5.5 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EGO52584.1 - 1.7e-05 24.1 0.0 4e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGO52584.1 - 0.00024 21.1 0.0 0.023 14.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGO52584.1 - 0.0011 18.1 0.0 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 EGO52584.1 - 0.0092 15.4 0.1 0.024 14.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGO52584.1 - 0.011 14.9 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGO52584.1 - 0.028 15.2 0.0 0.062 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGO52584.1 - 0.13 11.6 0.0 0.5 9.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EGO52584.1 - 0.28 11.1 4.8 0.2 11.6 0.1 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RRM_1 PF00076.17 EGO52585.1 - 7.7e-14 51.0 0.0 1.2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO52585.1 - 4.9e-11 42.4 0.0 7.5e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO52585.1 - 2.8e-08 33.4 0.0 5.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cep57_MT_bd PF06657.8 EGO52586.1 - 1.1e-26 92.5 1.4 1.1e-26 92.5 1.0 7.6 7 1 0 7 7 7 2 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EGO52586.1 - 4.3e-14 52.2 8.3 4.3e-14 52.2 5.7 8.4 6 3 0 6 6 6 2 Centrosome localisation domain of PPC89 DUF972 PF06156.8 EGO52586.1 - 0.1 12.9 0.3 0.1 12.9 0.2 9.0 4 1 4 8 8 8 0 Protein of unknown function (DUF972) UDPGT PF00201.13 EGO52586.1 - 0.38 9.2 1.5 0.74 8.2 1.0 1.4 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Ribophorin_II PF05817.9 EGO52587.1 - 8.6e-23 80.4 0.1 1.2e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Peptidase_M28 PF04389.12 EGO52588.1 - 4.1e-38 130.9 0.0 6e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 CDP-OH_P_transf PF01066.16 EGO52589.1 - 1.1e-15 57.7 8.3 1.1e-15 57.7 5.8 2.7 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PX PF00787.19 EGO52591.1 - 2.3e-21 75.7 0.0 2.6e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 PX domain Cid2 PF09774.4 EGO52592.1 - 0.44 10.6 2.3 0.52 10.4 0.1 2.2 2 0 0 2 2 2 0 Caffeine-induced death protein 2 Peptidase_S8 PF00082.17 EGO52593.1 - 2.4e-54 184.4 3.8 2.4e-54 184.4 2.6 1.7 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.15 EGO52593.1 - 1.7e-27 94.9 1.0 3.6e-27 93.9 0.7 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain Serglycin PF04360.7 EGO52593.1 - 0.71 9.5 7.0 2.1 8.0 4.8 1.8 1 0 0 1 1 1 0 Serglycin PX PF00787.19 EGO52594.1 - 3.3e-20 71.9 0.7 1.1e-19 70.3 0.0 2.2 3 0 0 3 3 2 1 PX domain BAR PF03114.13 EGO52594.1 - 1.2e-12 47.8 5.1 2.4e-12 46.8 3.5 1.4 1 1 0 1 1 1 1 BAR domain Vps5 PF09325.5 EGO52594.1 - 1.3e-12 47.5 12.1 2.1e-07 30.4 0.6 2.1 2 0 0 2 2 2 2 Vps5 C terminal like DUF3140 PF11338.3 EGO52594.1 - 0.0016 18.4 1.2 0.0036 17.3 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3140) IncA PF04156.9 EGO52594.1 - 0.0021 17.6 4.6 0.019 14.5 0.0 2.2 2 0 0 2 2 2 1 IncA protein Reo_sigmaC PF04582.7 EGO52594.1 - 0.0035 16.5 0.1 0.0055 15.9 0.1 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein FlaC_arch PF05377.6 EGO52594.1 - 0.06 13.2 2.5 0.43 10.5 0.1 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF3287 PF11690.3 EGO52594.1 - 0.25 11.4 3.5 2.4 8.2 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) eIF3_subunit PF08597.5 EGO52594.1 - 0.47 9.9 8.7 0.036 13.6 2.2 1.9 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF4404 PF14357.1 EGO52594.1 - 0.76 10.2 6.8 3.7 8.0 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) V_ATPase_I PF01496.14 EGO52594.1 - 1.6 6.4 6.1 3.4 5.4 0.5 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF724 PF05266.9 EGO52594.1 - 2.1 7.9 6.0 2.5 7.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) APG6 PF04111.7 EGO52594.1 - 9.5 5.1 9.0 1.9 7.4 0.2 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 LETM1 PF07766.8 EGO52595.1 - 8.2e-112 372.6 2.7 1.4e-111 371.8 1.9 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EGO52595.1 - 9.4e-05 21.8 0.0 0.067 12.7 0.0 3.1 3 0 0 3 3 3 2 SAP domain ADK PF00406.17 EGO52596.1 - 3.1e-37 127.7 0.0 3.3e-20 72.5 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EGO52596.1 - 2.3e-14 52.7 0.0 4.4e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EGO52596.1 - 1.3e-05 25.4 0.0 0.00028 21.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO52596.1 - 0.00012 21.9 0.0 0.00052 19.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO52596.1 - 0.00055 20.7 0.0 0.0026 18.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EGO52596.1 - 0.045 13.4 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Glyco_hydro_76 PF03663.9 EGO52597.1 - 9e-19 68.0 1.5 3e-11 43.3 0.0 2.8 3 0 0 3 3 3 2 Glycosyl hydrolase family 76 LicD PF04991.8 EGO52599.1 - 3e-27 96.0 0.6 4e-27 95.6 0.4 1.2 1 0 0 1 1 1 1 LicD family DUF2205 PF10224.4 EGO52600.1 - 0.013 15.0 2.3 0.031 13.8 1.6 1.7 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DUF2486 PF10667.4 EGO52601.1 - 0.023 15.2 3.7 0.023 15.2 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) DAOA PF15199.1 EGO52601.1 - 0.027 15.1 0.1 0.19 12.3 0.0 2.3 2 0 0 2 2 2 0 D-amino acid oxidase activator OmpH PF03938.9 EGO52601.1 - 6.5 6.6 16.8 0.58 10.0 0.6 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Glyco_hydro_18 PF00704.23 EGO52603.1 - 4e-81 273.1 0.1 1.7e-80 271.0 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1582 PF07621.6 EGO52603.1 - 0.028 14.3 0.1 0.068 13.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) DRAT PF07357.6 EGO52603.1 - 0.037 13.2 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) VMA21 PF09446.5 EGO52604.1 - 0.019 14.8 1.1 0.053 13.4 0.4 2.1 1 1 0 1 1 1 0 VMA21-like domain LRR_6 PF13516.1 EGO52605.1 - 1.8e-10 39.7 7.0 0.04 13.9 0.0 6.5 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 EGO52605.1 - 9.7e-08 31.4 12.3 0.0013 18.2 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGO52605.1 - 2.2e-06 26.9 1.9 5 7.5 0.0 5.8 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 EGO52605.1 - 0.0084 16.1 0.8 80 4.1 0.0 5.2 5 0 0 5 5 5 0 Leucine rich repeat LETM1 PF07766.8 EGO52605.1 - 0.044 12.8 0.0 0.044 12.8 0.0 2.2 3 0 0 3 3 3 0 LETM1-like protein LRR_8 PF13855.1 EGO52605.1 - 0.1 12.3 13.6 7.7 6.3 0.1 4.8 3 2 0 3 3 3 0 Leucine rich repeat SDA1 PF05285.7 EGO52605.1 - 0.59 9.3 15.5 0.83 8.8 10.7 1.2 1 0 0 1 1 1 0 SDA1 WBS_methylT PF12589.3 EGO52605.1 - 1.4 9.4 5.1 15 6.1 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome zf-H2C2_2 PF13465.1 EGO52606.1 - 1.3e-07 31.5 8.0 3.4e-06 27.0 0.7 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGO52606.1 - 0.00018 21.6 0.3 0.00018 21.6 0.2 3.3 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO52606.1 - 0.00059 19.9 0.3 0.00059 19.9 0.2 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO52606.1 - 0.39 10.9 3.4 4.3 7.6 0.3 2.8 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Fe_hyd_lg_C PF02906.9 EGO52608.1 - 3.5e-60 203.7 0.0 7.1e-60 202.6 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SUZ PF12752.2 EGO52609.1 - 2.6e-05 24.6 8.4 2.6e-05 24.6 5.8 2.7 3 2 0 3 3 3 1 SUZ domain ARGLU PF15346.1 EGO52609.1 - 1.2 8.9 16.1 0.07 12.9 4.9 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 DUF1754 PF08555.5 EGO52609.1 - 1.7 9.2 12.0 13 6.5 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) U1snRNP70_N PF12220.3 EGO52609.1 - 9 6.7 10.3 0.8 10.0 2.2 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Pkinase PF00069.20 EGO52611.1 - 1.6e-70 237.2 0.0 2.2e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO52611.1 - 1.8e-30 105.8 0.0 2.6e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGO52611.1 - 1.3e-14 54.3 0.9 8.7e-14 51.7 0.6 2.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGO52611.1 - 1.6e-09 37.1 0.0 3.5e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 EGO52611.1 - 0.0011 18.7 0.0 0.0045 16.8 0.0 2.0 1 1 0 1 1 1 1 C2 domain Kdo PF06293.9 EGO52611.1 - 0.022 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGO52611.1 - 0.056 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 EGO52611.1 - 0.087 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ATP_sub_h PF10775.4 EGO52612.1 - 1.9e-25 88.3 0.8 3.5e-25 87.5 0.6 1.4 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EGO52612.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 DOMON PF03351.12 EGO52613.1 - 9.3e-08 32.0 0.1 1.7e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 EGO52613.1 - 0.016 14.7 4.8 0.016 14.7 3.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) DUF4538 PF15061.1 EGO52613.1 - 0.36 10.1 2.4 10 5.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Pkinase PF00069.20 EGO52614.1 - 2e-67 227.0 0.0 2.5e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO52614.1 - 1.9e-30 105.8 0.0 2.5e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGO52614.1 - 0.0044 17.4 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGO52614.1 - 0.022 13.7 0.1 0.056 12.3 0.0 1.7 1 1 1 2 2 2 0 Kinase-like APH PF01636.18 EGO52614.1 - 0.03 14.0 0.1 0.97 9.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.27 EGO52616.1 - 1.2e-50 167.6 13.7 4.1e-10 39.1 0.9 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EGO52616.1 - 5.9e-16 57.4 1.1 1e-15 56.6 0.7 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 EGO52616.1 - 0.016 14.9 0.0 0.9 9.2 0.0 3.3 3 1 2 5 5 5 0 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EGO52616.1 - 0.065 12.3 0.0 1.7 7.6 0.0 2.5 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 EGO52616.1 - 0.11 10.6 0.3 4.3 5.3 0.0 2.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Cyclin_N PF00134.18 EGO52617.1 - 2.4e-08 33.6 1.3 4.3e-08 32.7 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain FliJ PF02050.11 EGO52617.1 - 0.67 10.0 6.7 1.2 9.1 1.6 2.6 3 0 0 3 3 3 0 Flagellar FliJ protein Dus PF01207.12 EGO52618.1 - 1e-27 96.7 0.0 4.9e-23 81.4 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) AIRC PF00731.15 EGO52619.1 - 5.5e-59 197.7 0.8 1e-58 196.9 0.5 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EGO52619.1 - 1.2e-49 167.9 0.0 2e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EGO52619.1 - 1.3e-10 41.3 0.2 1.6e-09 37.7 0.0 2.5 2 1 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGO52619.1 - 1.8e-07 30.7 0.0 4.3e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 EGO52619.1 - 5.2e-05 22.6 0.0 0.0021 17.3 0.0 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain XdhC_C PF13478.1 EGO52619.1 - 0.00097 19.4 0.0 0.084 13.1 0.0 2.5 2 0 0 2 2 2 1 XdhC Rossmann domain 2-Hacid_dh_C PF02826.14 EGO52619.1 - 0.0022 17.1 0.0 0.0042 16.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrpR_N PF06506.6 EGO52619.1 - 0.0029 17.0 0.1 0.015 14.6 0.0 2.1 2 0 0 2 2 2 1 Propionate catabolism activator NAD_binding_2 PF03446.10 EGO52619.1 - 0.05 13.4 0.0 1.6 8.5 0.0 2.6 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1126 PF06565.7 EGO52619.1 - 0.12 11.8 0.0 0.65 9.5 0.0 2.1 2 0 0 2 2 2 0 Repeat of unknown function (DUF1126) UPF0139 PF03669.8 EGO52620.1 - 5e-06 25.9 0.0 6.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) GDI PF00996.13 EGO52622.1 - 4.4e-39 134.0 0.0 7.1e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor Rad21_Rec8_N PF04825.8 EGO52623.1 - 3.1e-28 97.9 0.0 5.1e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EGO52623.1 - 1.4e-10 40.1 0.0 3.7e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EGO52623.1 - 0.065 12.8 1.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 ScpA/B protein ALO PF04030.9 EGO52625.1 - 1e-94 316.9 1.4 1.3e-94 316.6 1.0 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EGO52625.1 - 3.9e-31 107.3 0.1 6.4e-31 106.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pkinase PF00069.20 EGO52626.1 - 1.5e-57 194.7 0.0 2.3e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO52626.1 - 1.8e-35 122.2 0.0 2.4e-34 118.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO52626.1 - 0.00028 19.9 0.0 0.00047 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like NCA2 PF08637.5 EGO52626.1 - 0.0051 15.7 0.0 0.013 14.4 0.0 1.6 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 DUF607 PF04678.8 EGO52626.1 - 0.013 15.4 0.2 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF607 HOOK PF05622.7 EGO52626.1 - 0.051 11.3 4.7 0.085 10.6 3.2 1.2 1 0 0 1 1 1 0 HOOK protein APH PF01636.18 EGO52626.1 - 0.064 12.9 0.1 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3896 PF13035.1 EGO52626.1 - 0.82 9.7 2.7 5.5 7.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) APG6 PF04111.7 EGO52626.1 - 1.3 7.9 6.2 2.5 7.0 4.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 BTB PF00651.26 EGO52627.1 - 3.9e-28 97.6 0.3 1.3e-13 50.9 0.3 3.3 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.2 EGO52627.1 - 1e-09 38.6 0.0 2.1e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGO52627.1 - 2e-09 36.7 0.1 1.5e-05 24.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EGO52627.1 - 1.5e-07 31.7 0.0 3.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO52627.1 - 7.8e-07 29.1 0.0 9.4e-05 22.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO52627.1 - 8.2e-07 28.6 0.0 0.0031 17.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat zf-C2H2 PF00096.21 EGO52630.1 - 7.4e-09 35.4 12.3 0.00035 20.7 1.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO52630.1 - 2.2e-07 30.8 9.0 9.4e-07 28.8 0.8 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO52630.1 - 4.8e-05 23.4 10.6 0.0086 16.3 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EGO52630.1 - 0.015 15.5 3.4 0.035 14.3 1.0 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGO52630.1 - 0.061 13.4 0.7 0.061 13.4 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EGO52630.1 - 0.36 10.8 2.3 8.7 6.3 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 EGO52630.1 - 3.2 7.5 7.9 13 5.5 0.6 2.5 1 1 1 2 2 2 0 BED zinc finger Lipase_GDSL PF00657.17 EGO52633.1 - 6.3e-09 35.9 4.7 1.5e-08 34.7 3.2 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EGO52633.1 - 1.3e-08 35.2 0.2 7.6e-08 32.6 0.1 2.1 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EGO52633.1 - 0.19 11.4 0.4 4.1 7.1 0.0 2.3 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF2365 PF10157.4 EGO52635.1 - 0.012 15.4 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) PLU-1 PF08429.6 EGO52635.1 - 0.08 11.8 0.2 0.13 11.1 0.1 1.3 1 1 0 1 1 1 0 PLU-1-like protein FlgD_ig PF13860.1 EGO52635.1 - 0.11 12.2 0.2 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 FlgD Ig-like domain PHD PF00628.24 EGO52636.1 - 2.9e-12 46.0 6.4 2.9e-12 46.0 4.4 2.3 2 0 0 2 2 2 1 PHD-finger zf-HIT PF04438.11 EGO52636.1 - 3.6 7.2 8.0 0.13 11.9 0.8 2.1 2 0 0 2 2 2 0 HIT zinc finger SCO1-SenC PF02630.9 EGO52637.1 - 2.8e-61 206.1 0.0 4.1e-61 205.5 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EGO52637.1 - 7e-07 28.9 0.0 1.3e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EGO52637.1 - 0.00012 22.1 0.0 0.00028 20.9 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EGO52637.1 - 0.012 15.1 0.0 0.14 11.6 0.0 2.1 1 1 0 1 1 1 0 Redoxin Choline_kinase PF01633.15 EGO52638.1 - 5.7e-69 231.8 0.0 1.2e-68 230.7 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EGO52638.1 - 1.3e-22 78.9 0.0 2.5e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EGO52638.1 - 2.7e-07 30.5 0.1 5.7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3433 PF11915.3 EGO52639.1 - 4.4e-28 97.2 9.8 4.1e-27 94.1 0.5 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Serglycin PF04360.7 EGO52639.1 - 3.6 7.3 7.6 0.78 9.4 0.8 2.4 2 0 0 2 2 2 0 Serglycin CAF-1_p150 PF11600.3 EGO52641.1 - 3.3 7.0 29.1 0.12 11.7 1.9 2.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Hydrolase_6 PF13344.1 EGO52642.1 - 1.5e-25 89.0 0.0 3.3e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO52642.1 - 6.6e-15 54.5 0.0 2.3e-14 52.8 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EGO52642.1 - 2e-05 24.9 0.0 0.0043 17.3 0.0 3.4 2 1 2 4 4 4 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO52642.1 - 0.00015 22.2 0.0 3 8.1 0.0 3.4 2 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase TGF_beta PF00019.15 EGO52643.1 - 0.077 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Transforming growth factor beta like domain Zip PF02535.17 EGO52643.1 - 0.22 10.4 0.2 0.33 9.8 0.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Dicty_REP PF05086.7 EGO52643.1 - 1.4 6.5 3.5 2 6.0 2.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein OPT PF03169.10 EGO52644.1 - 1.5e-182 608.3 53.8 1.8e-182 608.1 37.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MoaE PF02391.12 EGO52646.1 - 6.4e-29 100.1 0.0 8.4e-29 99.7 0.0 1.1 1 0 0 1 1 1 1 MoaE protein G-patch PF01585.18 EGO52647.1 - 3.7e-10 39.4 2.1 1.2e-09 37.8 1.4 1.9 1 0 0 1 1 1 1 G-patch domain RRM_6 PF14259.1 EGO52647.1 - 1.1e-06 28.4 0.1 0.018 15.0 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 EGO52647.1 - 2.3e-06 26.5 1.9 5.1e-06 25.4 1.4 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EGO52647.1 - 0.00012 21.6 0.4 0.12 11.9 0.0 3.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO52647.1 - 0.00013 21.7 0.0 0.24 11.2 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 EGO52647.1 - 0.00017 21.4 4.3 0.00026 20.7 2.0 2.1 1 1 1 2 2 2 1 DExH-box splicing factor binding site zf-C2H2_2 PF12756.2 EGO52647.1 - 0.16 12.0 2.2 3.1 7.9 0.5 2.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RED_N PF07808.8 EGO52647.1 - 7.1 5.7 12.9 0.18 10.9 3.4 2.2 2 1 0 2 2 2 0 RED-like protein N-terminal region Asp PF00026.18 EGO52648.1 - 8.4e-70 235.5 3.7 1.1e-69 235.1 2.6 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO52648.1 - 5.3e-10 39.5 0.0 2.9e-09 37.0 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO52648.1 - 0.00097 19.5 2.3 4.3 7.9 0.0 3.8 4 0 0 4 4 4 2 Aspartyl protease gag-asp_proteas PF13975.1 EGO52648.1 - 0.0028 17.4 0.0 0.99 9.2 0.0 2.9 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 EGO52648.1 - 0.0076 15.8 0.0 0.023 14.2 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DPCD PF14913.1 EGO52649.1 - 0.027 13.5 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 DPCD protein family SAICAR_synt PF01259.13 EGO52651.1 - 1.9e-51 174.5 0.0 2.2e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase HATPase_c PF02518.21 EGO52653.1 - 1.2e-22 79.7 0.0 4.9e-22 77.7 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EGO52653.1 - 4.3e-20 72.0 0.0 4.4e-06 27.0 0.0 4.1 3 0 0 3 3 3 3 PAS domain Response_reg PF00072.19 EGO52653.1 - 4.9e-16 58.7 0.3 4.7e-11 42.6 0.0 3.0 2 0 0 2 2 2 2 Response regulator receiver domain PAS_8 PF13188.1 EGO52653.1 - 4.4e-13 48.5 0.0 4.7e-05 23.0 0.0 3.8 3 0 0 3 3 3 3 PAS domain PAS PF00989.19 EGO52653.1 - 6.2e-11 42.0 0.0 0.00015 21.4 0.0 3.8 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.5 EGO52653.1 - 1.6e-09 37.7 0.0 0.11 12.4 0.0 5.1 4 0 0 4 4 4 2 PAS fold HisKA PF00512.20 EGO52653.1 - 8.6e-08 32.0 0.2 7.1e-07 29.1 0.1 2.6 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EGO52653.1 - 6.5e-07 29.3 0.0 0.0054 16.7 0.0 3.2 2 1 0 2 2 2 2 PAS fold GAF_3 PF13492.1 EGO52653.1 - 0.035 14.2 0.0 2.5 8.2 0.0 2.5 2 0 0 2 2 2 0 GAF domain Dabb PF07876.7 EGO52654.1 - 4.3e-15 55.9 0.0 4.7e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Topo_Zn_Ribbon PF08272.6 EGO52654.1 - 0.18 11.1 0.3 9.4 5.6 0.0 2.5 2 1 0 2 2 2 0 Topoisomerase I zinc-ribbon-like DUF2894 PF11445.3 EGO52655.1 - 0.019 15.2 1.2 0.036 14.3 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Prominin PF05478.6 EGO52655.1 - 0.18 9.2 0.8 0.24 8.8 0.6 1.1 1 0 0 1 1 1 0 Prominin RNase_PH PF01138.16 EGO52658.1 - 4e-21 75.7 0.0 7.9e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Radial_spoke PF04712.7 EGO52658.1 - 8.2e-05 21.5 0.0 0.0001 21.2 0.0 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein RNase_PH_C PF03725.10 EGO52658.1 - 0.094 12.6 1.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 Abhydrolase_6 PF12697.2 EGO52659.1 - 3.9e-20 72.7 0.5 8.1e-20 71.6 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO52659.1 - 9.4e-11 41.6 0.0 5.2e-10 39.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO52659.1 - 2e-08 34.0 0.0 2.9e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EGO52659.1 - 0.00061 19.5 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EGO52659.1 - 0.027 13.7 0.0 0.087 12.0 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.6 EGO52659.1 - 0.098 12.3 0.1 2 8.1 0.0 2.4 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal L51_S25_CI-B8 PF05047.11 EGO52661.1 - 7.1e-12 44.8 0.0 9.1e-12 44.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.8 EGO52662.1 - 9.7e-45 151.3 0.7 1.3e-44 150.9 0.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Fumble PF03630.9 EGO52663.1 - 3.1e-128 427.4 0.0 2.2e-127 424.6 0.0 1.9 1 1 0 1 1 1 1 Fumble RGS PF00615.14 EGO52664.1 - 3.7e-05 23.8 0.1 0.0022 18.1 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF1348 PF07080.6 EGO52665.1 - 2e-57 193.0 7.7 2.4e-57 192.7 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) DUF4440 PF14534.1 EGO52665.1 - 3.9e-06 27.0 0.2 5.7e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 EGO52665.1 - 1.9e-05 25.0 1.1 2.8e-05 24.4 0.8 1.2 1 0 0 1 1 1 1 SnoaL-like domain Redoxin PF08534.5 EGO52666.1 - 1.4e-37 128.4 0.1 1.6e-37 128.3 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EGO52666.1 - 1.5e-12 47.2 0.1 2e-12 46.8 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Ribosomal_L24e PF01246.15 EGO52667.1 - 4.1e-31 106.6 0.3 4.1e-31 106.6 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e A_deamin PF02137.13 EGO52668.1 - 1.9e-72 244.4 0.0 2.4e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain NAC PF01849.13 EGO52669.1 - 9.8e-21 73.0 0.9 2.9e-20 71.5 0.2 1.9 2 0 0 2 2 2 1 NAC domain CBP4 PF07960.6 EGO52670.1 - 2.7e-40 136.9 2.5 4.2e-40 136.3 1.7 1.2 1 0 0 1 1 1 1 CBP4 DUF2852 PF11014.3 EGO52670.1 - 0.069 13.1 0.9 0.079 12.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) UPF0258 PF06789.7 EGO52670.1 - 0.072 13.1 0.2 0.09 12.8 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Seryl_tRNA_N PF02403.17 EGO52670.1 - 1.4 8.9 5.9 2.6 8.1 4.1 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain F-box-like PF12937.2 EGO52671.1 - 1.7e-11 43.6 0.2 3.1e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO52671.1 - 0.00037 20.0 0.2 0.00097 18.7 0.2 1.8 1 1 0 1 1 1 1 F-box domain MttA_Hcf106 PF02416.11 EGO52671.1 - 0.085 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 mttA/Hcf106 family Cation_efflux PF01545.16 EGO52672.1 - 4.4e-77 258.9 1.3 8.6e-77 257.9 0.9 1.4 1 1 0 1 1 1 1 Cation efflux family ATPgrasp_Ter PF15632.1 EGO52673.1 - 3.4e-06 26.0 0.0 5.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon HTH_39 PF14090.1 EGO52673.1 - 0.022 14.2 0.3 0.063 12.7 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Zn_clus PF00172.13 EGO52674.1 - 0.19 11.6 4.0 0.39 10.6 2.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ycf1 PF05758.7 EGO52674.1 - 0.21 9.2 2.3 0.25 9.0 1.6 1.1 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 EGO52674.1 - 1.6 6.6 7.0 2.3 6.1 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 EGO52674.1 - 9.7 4.3 10.4 14 3.8 7.2 1.3 1 0 0 1 1 1 0 Transmembrane protein tRNA_int_end_N2 PF12928.2 EGO52675.1 - 0.15 11.5 0.1 7.5 6.0 0.0 2.1 1 1 1 2 2 2 0 tRNA-splicing endonuclease subunit sen54 N-term PLA2_B PF01735.13 EGO52676.1 - 2e-206 685.9 1.0 2.3e-206 685.7 0.7 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Histidinol_dh PF00815.15 EGO52678.1 - 1.4e-181 603.6 8.6 1.9e-181 603.2 5.9 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EGO52678.1 - 1e-25 89.1 0.1 2.1e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EGO52678.1 - 1.2e-10 41.4 0.2 1.2e-10 41.4 0.2 2.5 3 0 0 3 3 3 1 Phosphoribosyl-ATP pyrophosphohydrolase TFIID-31kDa PF02291.10 EGO52679.1 - 1e-23 83.5 0.0 4.7e-23 81.3 0.0 1.9 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Peptidase_S9 PF00326.16 EGO52679.1 - 0.11 11.7 0.2 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family LNS2 PF08235.8 EGO52680.1 - 1.6e-71 238.9 0.0 2.7e-71 238.2 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EGO52680.1 - 3e-40 136.3 0.0 9.1e-40 134.7 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EGO52680.1 - 0.0019 17.5 0.0 0.19 11.0 0.0 2.5 2 0 0 2 2 2 2 HAD superfamily, subfamily IIIB (Acid phosphatase) fn3 PF00041.16 EGO52682.1 - 1.3e-07 31.6 0.0 2.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain BTP PF05232.7 EGO52682.1 - 1.2 8.9 3.6 2.2 8.0 2.5 1.4 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family Cmc1 PF08583.5 EGO52683.1 - 4e-17 61.7 0.8 4e-17 61.7 0.6 1.8 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EGO52683.1 - 0.28 11.1 2.2 3 7.8 1.3 2.2 1 1 0 1 1 1 0 CHCH domain Glyco_hydro_47 PF01532.15 EGO52684.1 - 1.2e-162 541.6 0.0 1.4e-162 541.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 EGO52684.1 - 0.077 11.2 0.0 1.8 6.7 0.0 2.3 2 1 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Utp11 PF03998.8 EGO52685.1 - 3.9e-58 197.1 28.9 4.6e-58 196.9 20.1 1.1 1 0 0 1 1 1 1 Utp11 protein Bd3614_N PF14442.1 EGO52685.1 - 0.0089 16.0 0.8 0.0089 16.0 0.5 2.1 2 0 0 2 2 2 1 Bd3614-like deaminase N-terminal FTA4 PF13093.1 EGO52685.1 - 0.52 9.7 10.9 0.017 14.5 0.9 2.2 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 V_ATPase_I PF01496.14 EGO52685.1 - 6 4.5 12.0 1.5 6.5 4.4 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DAO PF01266.19 EGO52687.1 - 1.5e-24 86.6 0.1 2.8e-24 85.7 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO52687.1 - 0.018 13.8 0.1 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EGO52687.1 - 0.021 15.2 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EGO52687.1 - 0.031 14.5 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 EGO52687.1 - 0.056 13.3 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGO52687.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Maf PF02545.9 EGO52688.1 - 6.2e-45 152.7 0.0 8.1e-45 152.3 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein Mis14 PF08641.7 EGO52688.1 - 0.028 14.5 3.8 0.5 10.4 0.3 2.6 2 1 0 2 2 2 0 Kinetochore protein Mis14 like AAA_9 PF12781.2 EGO52688.1 - 0.054 12.3 0.4 1.9 7.2 0.1 2.8 2 1 0 2 2 2 0 ATP-binding dynein motor region D5 tRNA-synt_2b PF00587.20 EGO52689.1 - 2.2e-50 170.6 0.0 3e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGO52689.1 - 9.3e-09 35.1 0.0 1.9e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_His PF13393.1 EGO52689.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase SprB PF13573.1 EGO52689.1 - 0.25 10.9 1.5 0.53 9.9 1.0 1.5 1 0 0 1 1 1 0 SprB repeat LOH1CR12 PF10158.4 EGO52690.1 - 0.086 12.6 1.9 0.15 11.8 0.7 1.8 2 0 0 2 2 2 0 Tumour suppressor protein Amidohydro_1 PF01979.15 EGO52691.1 - 1.8e-60 205.3 2.4 2.7e-60 204.7 1.6 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EGO52691.1 - 4.2e-54 181.8 5.1 8.5e-54 180.8 2.2 2.2 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EGO52691.1 - 1.4e-42 143.5 0.3 5.3e-42 141.7 0.0 2.0 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 EGO52691.1 - 1.5e-39 134.0 0.1 2.9e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EGO52691.1 - 1.4e-06 27.9 4.6 3.9e-06 26.5 3.2 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGO52691.1 - 7.5e-05 22.1 0.3 0.0011 18.3 0.0 2.5 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_2 PF04909.9 EGO52691.1 - 0.057 12.9 0.0 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Amidohydrolase HMG_box PF00505.14 EGO52692.1 - 2.8e-06 27.5 1.1 6e-06 26.4 0.1 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO52692.1 - 0.00063 20.0 0.1 0.00063 20.0 0.1 2.9 3 0 0 3 3 3 1 HMG-box domain Het-C PF07217.6 EGO52693.1 - 8.2e-267 886.3 0.0 1e-266 885.9 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Pkinase PF00069.20 EGO52694.1 - 4.5e-60 202.9 0.1 5.3e-60 202.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO52694.1 - 1.2e-19 70.3 0.0 1.8e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO52694.1 - 1.8e-08 34.4 0.0 7.1e-06 25.9 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGO52694.1 - 0.009 15.6 0.1 0.023 14.2 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 EGO52694.1 - 0.059 12.3 0.0 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EGO52694.1 - 0.074 12.0 0.1 0.14 11.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Scm3 PF10384.4 EGO52695.1 - 1.4e-21 75.7 0.0 2.8e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 APG6 PF04111.7 EGO52696.1 - 5.9e-127 423.0 0.1 9e-127 422.4 0.1 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 SPX PF03105.14 EGO52696.1 - 6.1e-05 22.9 0.2 0.00015 21.6 0.2 1.6 1 1 0 1 1 1 1 SPX domain DUF342 PF03961.8 EGO52696.1 - 0.0089 14.4 6.5 0.012 14.0 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) DUF3373 PF11853.3 EGO52696.1 - 0.074 11.5 0.3 0.12 10.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) NAM-associated PF14303.1 EGO52696.1 - 1.3 9.3 11.8 3 8.1 8.2 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain V_ATPase_I PF01496.14 EGO52696.1 - 3.3 5.4 8.4 4.5 4.9 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ERM PF00769.14 EGO52696.1 - 4.4 6.7 30.6 0.034 13.6 13.9 2.4 2 1 0 2 2 2 0 Ezrin/radixin/moesin family AAA PF00004.24 EGO52697.1 - 6e-12 45.9 0.0 1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGO52697.1 - 0.0058 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGO52697.1 - 0.006 16.3 0.0 0.022 14.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain CPT PF07931.7 EGO52697.1 - 0.014 15.0 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Nop14 PF04147.7 EGO52697.1 - 0.019 12.9 7.1 0.026 12.4 4.9 1.1 1 0 0 1 1 1 0 Nop14-like family AAA_22 PF13401.1 EGO52697.1 - 0.076 13.1 0.1 0.2 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2457 PF10446.4 EGO52697.1 - 0.7 8.5 16.4 1.9 7.1 11.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 EGO52697.1 - 1.2 8.3 10.7 2.2 7.4 7.4 1.3 1 0 0 1 1 1 0 SDA1 Zn_clus PF00172.13 EGO52698.1 - 4.8e-08 32.7 11.1 8.3e-08 32.0 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGO52698.1 - 3.3e-07 29.4 0.4 6.6e-07 28.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NifW PF03206.9 EGO52698.1 - 0.0024 17.9 0.3 0.0051 16.9 0.2 1.5 1 0 0 1 1 1 1 Nitrogen fixation protein NifW AlaDh_PNT_N PF05222.10 EGO52699.1 - 8.5e-30 103.5 0.0 1.4e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EGO52699.1 - 9.8e-18 64.2 0.1 1.4e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IMPDH PF00478.20 EGO52700.1 - 3.4e-134 447.1 2.7 4.2e-134 446.8 1.8 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EGO52700.1 - 8.5e-17 60.6 0.1 1.4e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 EGO52700.1 - 1.8e-09 37.2 1.1 6.6e-05 22.2 0.8 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 EGO52700.1 - 1.4e-08 34.0 1.5 7.2e-08 31.6 0.4 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EGO52700.1 - 0.0018 17.6 4.0 13 4.9 0.1 2.5 2 1 0 2 2 2 1 Histidine biosynthesis protein PK PF00224.16 EGO52700.1 - 0.015 13.9 0.0 0.056 12.0 0.0 1.9 2 1 0 2 2 2 0 Pyruvate kinase, barrel domain ThiG PF05690.9 EGO52700.1 - 0.035 13.1 1.4 0.04 13.0 0.2 1.6 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF1273 PF06908.6 EGO52700.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) RasGAP_C PF03836.10 EGO52701.1 - 7e-51 171.6 3.5 3.9e-50 169.2 2.4 2.5 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EGO52701.1 - 3e-45 154.3 0.0 1.1e-44 152.4 0.0 2.1 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EGO52701.1 - 2.6e-28 94.8 42.6 0.027 14.1 0.2 15.8 16 0 0 16 16 16 10 IQ calmodulin-binding motif CH PF00307.26 EGO52701.1 - 1.7e-09 37.6 0.0 7.2e-09 35.6 0.0 2.1 1 0 0 1 1 1 1 Calponin homology (CH) domain GIT_SHD PF08518.6 EGO52702.1 - 1.7e-23 81.6 4.7 1.5e-14 53.0 1.8 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Cep57_MT_bd PF06657.8 EGO52702.1 - 0.033 14.1 0.1 0.033 14.1 0.1 3.5 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 IncA PF04156.9 EGO52702.1 - 0.042 13.4 39.4 0.038 13.5 10.6 2.9 2 1 1 3 3 3 0 IncA protein APG6 PF04111.7 EGO52702.1 - 0.07 12.1 34.5 0.008 15.2 9.0 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 PSII_Pbs27 PF13326.1 EGO52702.1 - 0.12 12.4 3.5 0.36 10.7 1.1 2.8 2 0 0 2 2 2 0 Photosystem II Pbs27 GAS PF13851.1 EGO52702.1 - 0.3 10.2 32.5 0.82 8.8 6.3 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EGO52702.1 - 0.94 9.3 31.9 0.54 10.1 10.8 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1843 PF08898.5 EGO52702.1 - 1.5 8.9 5.8 0.46 10.5 0.2 3.1 2 1 1 3 3 2 0 Domain of unknown function (DUF1843) TPR_MLP1_2 PF07926.7 EGO52702.1 - 2.5 7.8 32.2 0.19 11.4 7.4 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Vps53_N PF04100.7 EGO52702.1 - 4.4 5.9 14.3 0.23 10.2 1.9 2.5 2 0 0 2 2 2 0 Vps53-like, N-terminal DUF4407 PF14362.1 EGO52702.1 - 5.9 5.7 25.7 2.5 6.9 7.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) AlphaC_N PF08829.5 EGO52702.1 - 6.9 5.9 7.9 0.13 11.5 0.2 1.9 2 0 0 2 2 2 0 Alpha C protein N terminal Mnd1 PF03962.10 EGO52702.1 - 8.4 6.0 34.7 0.097 12.3 7.6 3.0 3 0 0 3 3 3 0 Mnd1 family FUSC PF04632.7 EGO52702.1 - 9.6 4.4 15.7 0.78 8.1 7.3 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family Ssu72 PF04722.8 EGO52704.1 - 4.4e-85 283.9 0.0 5.1e-85 283.7 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SH3_1 PF00018.23 EGO52705.1 - 3.9e-10 38.9 0.1 7.3e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGO52705.1 - 1.8e-09 37.0 0.2 4.1e-09 35.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGO52705.1 - 0.00038 19.8 0.0 0.001 18.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain DUF1980 PF09323.5 EGO52705.1 - 5 6.8 4.5 8.6 6.0 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Menin PF05053.8 EGO52705.1 - 7.3 4.6 6.3 11 4.0 4.3 1.2 1 0 0 1 1 1 0 Menin NAD_binding_1 PF00175.16 EGO52706.1 - 1.4e-30 106.0 0.0 2.4e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGO52706.1 - 3.3e-22 78.4 0.0 6.7e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGO52706.1 - 1.4e-08 34.7 0.0 7.5e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EGO52706.1 - 0.00038 20.4 0.0 0.00093 19.1 0.0 1.7 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF3807 PF12720.2 EGO52707.1 - 4.9e-55 186.3 10.1 6.2e-55 185.9 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Ribosomal_60s PF00428.14 EGO52707.1 - 0.063 13.6 0.2 0.063 13.6 0.2 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Fungal_trans PF04082.13 EGO52708.1 - 6.2e-09 35.1 0.0 5.7e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO52708.1 - 7.9e-09 35.2 11.8 1.3e-08 34.6 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EGO52708.1 - 9.2 6.5 15.5 1.9 8.7 6.3 2.6 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region MARVEL PF01284.18 EGO52709.1 - 1.4e-07 31.4 11.0 1.4e-07 31.4 7.7 2.3 2 1 0 2 2 2 1 Membrane-associating domain Herpes_TAF50 PF03326.8 EGO52709.1 - 9.5 5.0 24.3 13 4.6 16.9 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) TFR_dimer PF04253.10 EGO52710.1 - 7.8e-22 77.1 0.0 1.5e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EGO52710.1 - 4.1e-15 55.9 0.0 7.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EGO52710.1 - 6e-07 29.1 0.0 1.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EGO52710.1 - 0.0024 17.4 0.0 0.0045 16.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 CCDC155 PF14662.1 EGO52710.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Dor1 PF04124.7 EGO52710.1 - 0.26 9.6 0.8 0.35 9.2 0.5 1.2 1 0 0 1 1 1 0 Dor1-like family Prominin PF05478.6 EGO52710.1 - 0.54 7.7 0.2 0.74 7.2 0.2 1.1 1 0 0 1 1 1 0 Prominin MFS_1 PF07690.11 EGO52711.1 - 5.3e-45 153.6 21.7 2.8e-30 105.2 4.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO52711.1 - 1.1e-11 43.9 12.1 2.3e-11 42.9 3.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Myc_N PF01056.13 EGO52711.1 - 0.5 9.4 1.1 0.76 8.8 0.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Atg14 PF10186.4 EGO52713.1 - 1.4e-88 296.7 0.1 1.7e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EGO52713.1 - 0.0095 15.5 3.4 0.014 15.0 2.4 1.2 1 0 0 1 1 1 1 IncA protein ADIP PF11559.3 EGO52713.1 - 0.02 14.7 8.3 0.034 14.0 5.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Mnd1 PF03962.10 EGO52713.1 - 0.039 13.6 5.5 0.06 13.0 3.8 1.2 1 0 0 1 1 1 0 Mnd1 family HXXSHH PF07586.6 EGO52713.1 - 0.14 11.0 1.3 0.25 10.2 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DDE_Tnp_1_5 PF13737.1 EGO52714.1 - 0.14 12.3 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 Transposase DDE domain NUP50 PF08911.6 EGO52714.1 - 3.9 7.9 6.2 5.5 7.4 0.3 2.7 1 1 1 2 2 2 0 NUP50 (Nucleoporin 50 kDa) Spc7_N PF15402.1 EGO52715.1 - 2.1e-254 846.7 68.1 2.5e-191 638.1 23.3 3.1 1 1 1 2 2 2 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EGO52715.1 - 1e-124 415.5 11.7 1.9e-124 414.5 8.1 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 EGO52715.1 - 6.6e-21 73.7 1.0 1.3e-20 72.7 0.7 1.5 1 0 0 1 1 1 1 Spc7_C2 IncA PF04156.9 EGO52715.1 - 0.00013 21.6 11.4 0.00013 21.6 7.9 2.8 3 0 0 3 3 3 1 IncA protein Ribosomal_S17 PF00366.15 EGO52716.1 - 8e-31 105.8 1.0 1.2e-30 105.3 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 SWI-SNF_Ssr4 PF08549.5 EGO52717.1 - 0 1082.5 10.2 0 1082.3 7.0 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) 6PGD PF00393.14 EGO52718.1 - 3e-135 450.0 0.0 3.8e-135 449.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EGO52718.1 - 4e-53 179.5 0.0 6.9e-53 178.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EGO52718.1 - 0.0062 16.5 0.0 0.019 15.0 0.0 1.8 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 EGO52718.1 - 0.098 11.7 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PGK PF00162.14 EGO52718.1 - 0.099 11.1 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase RRM_1 PF00076.17 EGO52719.1 - 1.3e-17 63.1 0.1 2.1e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO52719.1 - 8.1e-13 48.1 0.0 1.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO52719.1 - 4.8e-05 23.1 0.0 8.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EGO52719.1 - 0.1 12.1 0.2 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain Glyco_hydro_15 PF00723.16 EGO52720.1 - 1.2e-51 175.7 0.0 4.9e-47 160.4 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 TPT PF03151.11 EGO52721.1 - 2.3e-32 111.7 14.3 2.3e-32 111.7 9.9 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EGO52721.1 - 0.00026 21.0 34.2 0.00036 20.5 3.8 2.8 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EGO52721.1 - 0.00028 19.9 22.3 0.00028 19.9 15.5 1.9 1 1 1 2 2 2 1 UAA transporter family Bromo_TP PF07524.8 EGO52722.1 - 5.7e-10 38.7 0.0 1.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated TAFII55_N PF04658.8 EGO52723.1 - 3.1e-52 176.3 0.0 5.6e-52 175.4 0.0 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region Sigma70_ner PF04546.8 EGO52723.1 - 0.0063 16.1 5.6 0.0063 16.1 3.9 1.7 2 0 0 2 2 2 1 Sigma-70, non-essential region Ribosomal_60s PF00428.14 EGO52723.1 - 2.5 8.5 12.9 1.7 9.0 6.4 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Nop14 PF04147.7 EGO52723.1 - 2.8 5.7 16.6 3.8 5.2 11.5 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L37 PF08561.5 EGO52724.1 - 8.5e-37 124.6 5.6 2e-28 97.7 0.7 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L37 DUF2011 PF09428.5 EGO52724.1 - 3.9 7.3 9.6 18 5.1 6.6 1.8 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) NDUFB10 PF10249.4 EGO52725.1 - 0.0066 16.5 0.0 0.0075 16.4 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.9 EGO52725.1 - 0.066 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 HWE histidine kinase RRM_1 PF00076.17 EGO52726.1 - 6.9e-38 128.1 0.0 2.3e-19 68.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO52726.1 - 4.5e-31 106.6 0.0 4.1e-17 61.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO52726.1 - 4.8e-17 61.5 0.0 2e-09 37.1 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EGO52726.1 - 0.0036 15.8 22.2 0.0039 15.7 15.4 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Mem_trans PF03547.13 EGO52726.1 - 0.019 13.2 3.1 0.018 13.3 2.2 1.1 1 0 0 1 1 1 0 Membrane transport protein Daxx PF03344.10 EGO52726.1 - 0.021 13.3 23.8 0.023 13.1 16.5 1.2 1 0 0 1 1 1 0 Daxx Family SET_assoc PF11767.3 EGO52726.1 - 0.036 13.3 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Hid1 PF12722.2 EGO52726.1 - 0.33 8.5 13.3 0.37 8.4 9.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIF_alpha PF05793.7 EGO52726.1 - 0.76 8.0 40.9 1.2 7.4 28.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SR-25 PF10500.4 EGO52726.1 - 6.6 6.1 33.9 13 5.1 23.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein KIF1B PF12423.3 EGO52729.1 - 0.27 11.2 2.4 0.34 10.9 1.1 1.6 2 0 0 2 2 2 0 Kinesin protein 1B WH2 PF02205.15 EGO52730.1 - 3.1e-08 32.9 4.0 5.4e-08 32.1 0.3 3.0 3 0 0 3 3 3 1 WH2 motif PAT1 PF09770.4 EGO52732.1 - 9 4.3 15.6 12 4.0 10.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 2TM PF13239.1 EGO52733.1 - 0.031 14.3 4.5 2.9 8.0 0.0 3.2 2 1 1 3 3 3 0 2TM domain DUF4131 PF13567.1 EGO52733.1 - 0.82 9.0 6.5 3.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CHORD PF04968.7 EGO52734.1 - 8.7e-35 118.7 17.5 4.4e-26 90.9 3.6 3.2 2 1 1 3 3 3 3 CHORD CS PF04969.11 EGO52734.1 - 9.6e-17 61.3 0.2 1.5e-16 60.6 0.1 1.3 1 0 0 1 1 1 1 CS domain DUF836 PF05768.9 EGO52735.1 - 4.8e-14 52.3 0.0 5.8e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 EGO52735.1 - 0.0033 17.3 0.1 0.0093 15.9 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin HpcH_HpaI PF03328.9 EGO52736.1 - 8.3e-34 116.3 0.0 9.7e-34 116.1 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 EGO52736.1 - 0.0042 16.3 0.1 3.1 6.9 0.0 3.1 3 0 0 3 3 3 2 Phosphoenolpyruvate phosphomutase PK PF00224.16 EGO52736.1 - 0.057 12.0 0.0 0.14 10.7 0.0 1.6 2 0 0 2 2 2 0 Pyruvate kinase, barrel domain Radical_SAM PF04055.16 EGO52736.1 - 0.063 13.4 0.0 0.39 10.8 0.0 1.9 1 1 0 2 2 2 0 Radical SAM superfamily IU_nuc_hydro PF01156.14 EGO52738.1 - 3.5e-56 190.7 0.0 1.2e-45 156.0 0.0 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase Transketolase_C PF02780.15 EGO52738.1 - 0.086 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Transketolase, C-terminal domain Nucleo_P87 PF07267.6 EGO52740.1 - 0.59 8.7 3.2 1.1 7.8 2.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Rhomboid PF01694.17 EGO52742.1 - 2.8e-17 63.0 13.6 2.8e-17 63.0 9.5 1.9 2 0 0 2 2 2 1 Rhomboid family PhoD PF09423.5 EGO52743.1 - 1.6e-06 27.0 0.0 1.6e-06 27.0 0.0 2.5 3 0 0 3 3 3 2 PhoD-like phosphatase HLH PF00010.21 EGO52746.1 - 3.1e-14 52.3 1.0 6.1e-14 51.4 0.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Aldedh PF00171.17 EGO52747.1 - 7.2e-106 354.2 0.0 8.7e-106 354.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SKG6 PF08693.5 EGO52748.1 - 0.022 14.0 3.3 0.022 14.0 2.3 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EGO52748.1 - 0.086 11.0 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CBFD_NFYB_HMF PF00808.18 EGO52749.1 - 1.7e-10 40.7 0.1 2.9e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGO52749.1 - 1.9e-05 24.6 0.0 3.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SLD3 PF08639.5 EGO52750.1 - 1.6e-155 518.5 4.0 1.6e-155 518.5 2.8 2.7 3 0 0 3 3 3 1 DNA replication regulator SLD3 Pkinase PF00069.20 EGO52751.1 - 1.2e-68 231.0 0.0 3.6e-68 229.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO52751.1 - 2.2e-36 125.2 0.0 3.7e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO52751.1 - 4.7e-07 29.0 0.0 9.5e-07 28.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGO52751.1 - 0.094 11.5 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Homeobox PF00046.24 EGO52753.1 - 2e-14 52.9 1.1 2e-14 52.9 0.7 1.8 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EGO52753.1 - 0.00033 20.2 0.5 0.0012 18.4 0.1 2.2 3 0 0 3 3 3 1 Homeobox KN domain HAD_2 PF13419.1 EGO52754.1 - 5.5e-16 59.2 0.0 7e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO52754.1 - 3.4e-09 36.2 0.0 6.2e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EGO52754.1 - 1.2e-08 35.6 0.0 1.6e-06 28.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGO52754.1 - 0.00016 21.9 0.0 0.00029 21.0 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EGO52754.1 - 0.00017 21.4 0.0 0.061 13.2 0.0 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase GHL6 PF14871.1 EGO52754.1 - 0.037 14.0 0.2 0.087 12.8 0.0 1.7 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 TPR_12 PF13424.1 EGO52755.1 - 7.2e-10 38.6 3.6 9.3e-06 25.4 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGO52755.1 - 8.6e-06 25.3 1.5 0.002 17.7 0.2 2.1 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGO52755.1 - 3.5e-05 23.2 0.0 0.028 14.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO52755.1 - 3.8e-05 23.1 0.4 0.00028 20.4 0.0 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGO52755.1 - 5.1e-05 22.8 0.2 0.0092 15.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGO52755.1 - 6e-05 22.8 0.8 0.00027 20.7 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO52755.1 - 6.2e-05 23.5 0.2 0.00058 20.4 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGO52755.1 - 0.0056 17.2 0.6 0.23 12.2 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO52755.1 - 0.008 15.8 0.4 0.12 12.2 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGO52755.1 - 0.015 15.5 0.7 0.088 13.1 0.3 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.2 EGO52755.1 - 0.024 14.6 0.4 3 7.9 0.0 2.8 2 1 1 3 3 3 0 Tetratrico peptide repeat TPR_6 PF13174.1 EGO52755.1 - 0.12 12.8 1.4 2.3 8.8 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat GN3L_Grn1 PF08701.6 EGO52756.1 - 5.8e-25 87.0 17.2 1e-24 86.2 11.9 1.4 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EGO52756.1 - 5.1e-21 74.7 0.1 3.3e-14 52.8 0.0 2.8 2 1 1 3 3 3 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGO52756.1 - 2.9e-08 33.7 5.1 0.00083 19.2 0.3 3.4 2 2 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 EGO52756.1 - 6.1e-07 29.0 0.0 0.029 13.7 0.0 2.7 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EGO52756.1 - 0.00044 19.4 1.2 0.00052 19.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EGO52756.1 - 0.00081 18.7 0.0 0.014 14.6 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EGO52756.1 - 0.00089 19.7 0.0 0.69 10.4 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EGO52756.1 - 0.029 14.4 0.0 8.3 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EGO52756.1 - 0.037 12.8 0.9 0.057 12.1 0.0 1.7 2 0 0 2 2 2 0 ArgK protein MobB PF03205.9 EGO52756.1 - 0.069 12.8 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGO52756.1 - 0.074 13.0 4.6 0.13 12.2 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain cobW PF02492.14 EGO52756.1 - 0.08 12.3 0.0 2 7.8 0.0 2.6 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Nop14 PF04147.7 EGO52756.1 - 2.2 6.1 21.3 3.3 5.5 14.7 1.2 1 0 0 1 1 1 0 Nop14-like family RNB PF00773.14 EGO52757.1 - 6.3e-96 321.4 0.2 9.5e-96 320.8 0.2 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EGO52757.1 - 5.3e-10 39.5 0.1 1.6e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 EGO52757.1 - 0.12 11.9 0.0 0.35 10.4 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease B OB domain CRC_subunit PF08624.5 EGO52758.1 - 1.8e-54 183.4 0.0 2.6e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Trs65 PF12735.2 EGO52759.1 - 7.2e-82 275.1 0.2 2.5e-81 273.3 0.0 2.2 3 1 0 3 3 3 1 TRAPP trafficking subunit Trs65 Med3 PF11593.3 EGO52759.1 - 0.025 13.8 9.9 0.036 13.3 6.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FF PF01846.14 EGO52760.1 - 2.6e-53 177.7 11.3 1.2e-13 50.7 0.0 6.8 6 0 0 6 6 6 6 FF domain WW PF00397.21 EGO52760.1 - 5.1e-18 64.6 14.8 6.9e-10 38.6 2.7 2.6 2 0 0 2 2 2 2 WW domain PRP38_assoc PF12871.2 EGO52760.1 - 0.0021 18.5 23.0 0.0021 18.5 15.9 8.1 3 1 2 5 5 5 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Dimer_Tnp_hAT PF05699.9 EGO52761.1 - 9.3e-06 25.1 0.1 9.8e-06 25.1 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ABC_tran PF00005.22 EGO52762.1 - 1.9e-33 115.6 0.0 7.6e-16 58.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGO52762.1 - 9.6e-15 55.3 12.1 2.7e-05 24.2 0.1 4.9 3 2 2 5 5 5 4 AAA domain SMC_N PF02463.14 EGO52762.1 - 4.9e-10 39.0 0.8 0.0053 16.0 0.0 3.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EGO52762.1 - 1.3e-07 31.0 0.2 0.43 9.5 0.1 4.5 5 0 0 5 5 5 2 AAA ATPase domain AAA_17 PF13207.1 EGO52762.1 - 9.3e-07 29.6 0.4 0.073 13.8 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 EGO52762.1 - 1.5e-05 25.1 0.1 0.028 14.6 0.0 2.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGO52762.1 - 3.3e-05 24.1 0.2 0.24 11.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGO52762.1 - 3.5e-05 23.9 0.0 0.027 14.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EGO52762.1 - 0.00028 20.6 1.8 0.028 14.1 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EGO52762.1 - 0.00046 19.7 2.0 0.028 13.8 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain DUF258 PF03193.11 EGO52762.1 - 0.00058 19.0 0.0 0.91 8.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EGO52762.1 - 0.00058 20.2 0.0 0.072 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGO52762.1 - 0.00096 18.6 1.1 1.5 8.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.17 EGO52762.1 - 0.0017 18.5 0.1 0.84 9.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 EGO52762.1 - 0.0017 18.3 0.2 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EGO52762.1 - 0.0019 17.0 0.0 0.12 11.2 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.1 EGO52762.1 - 0.002 18.0 0.0 0.17 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 EGO52762.1 - 0.0025 17.3 0.1 1.9 7.9 0.0 2.7 2 0 0 2 2 2 1 Virulence-associated protein E AAA_16 PF13191.1 EGO52762.1 - 0.0026 17.7 0.1 0.89 9.5 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain Thymidylate_kin PF02223.12 EGO52762.1 - 0.0032 16.8 0.1 1.2 8.4 0.0 2.9 3 0 0 3 3 3 1 Thymidylate kinase NACHT PF05729.7 EGO52762.1 - 0.0037 16.9 1.1 0.72 9.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 EGO52762.1 - 0.0039 16.8 0.5 0.035 13.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 EGO52762.1 - 0.0093 15.6 0.4 0.59 9.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) Miro PF08477.8 EGO52762.1 - 0.013 15.9 0.0 1.3 9.5 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein AAA_13 PF13166.1 EGO52762.1 - 0.014 13.9 0.0 0.014 13.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.10 EGO52762.1 - 0.021 13.5 0.0 0.19 10.3 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 EGO52762.1 - 0.035 13.5 0.6 8.1 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGO52762.1 - 0.04 13.4 0.1 0.71 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EGO52762.1 - 0.12 12.0 2.1 4.7 6.8 0.1 2.5 2 0 0 2 2 2 0 NTPase T2SE PF00437.15 EGO52762.1 - 0.17 10.7 1.4 1.5 7.6 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_14 PF13173.1 EGO52762.1 - 0.26 11.1 3.4 14 5.5 0.1 3.6 3 2 1 4 4 3 0 AAA domain PduV-EutP PF10662.4 EGO52762.1 - 0.33 10.4 0.1 0.33 10.4 0.1 2.9 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EGO52762.1 - 0.34 10.4 2.2 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 EGO52763.1 - 1.1e-64 218.0 0.0 2.1e-64 217.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EGO52763.1 - 1.1e-26 92.2 9.9 7e-15 54.4 0.4 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EGO52763.1 - 1.8e-14 53.3 0.0 5.5e-14 51.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain POR PF01558.13 EGO52763.1 - 0.026 14.4 0.1 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase SIR2 PF02146.12 EGO52765.1 - 6.2e-28 97.7 0.0 1.9e-27 96.1 0.0 1.8 1 1 0 1 1 1 1 Sir2 family Med16 PF11635.3 EGO52766.1 - 2.1e-105 353.3 0.0 2.9e-105 352.9 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 DUF3500 PF12006.3 EGO52767.1 - 2.3e-106 355.2 0.0 2.7e-106 355.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) CENP-F_leu_zip PF10473.4 EGO52768.1 - 0.00039 20.2 8.4 0.12 12.2 0.3 2.2 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bacillus_HBL PF05791.6 EGO52768.1 - 0.0006 19.2 10.0 0.0083 15.5 2.2 2.6 1 1 1 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) CENP-Q PF13094.1 EGO52768.1 - 0.0022 18.0 4.5 0.0022 18.0 3.1 2.7 1 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Reo_sigmaC PF04582.7 EGO52768.1 - 0.0045 16.2 0.4 0.0045 16.2 0.3 2.1 1 1 0 1 1 1 1 Reovirus sigma C capsid protein Laminin_II PF06009.7 EGO52768.1 - 0.0063 16.2 8.7 0.044 13.5 0.5 2.5 2 0 0 2 2 2 1 Laminin Domain II Spc7 PF08317.6 EGO52768.1 - 0.011 14.4 1.3 0.011 14.4 0.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Myosin_tail_1 PF01576.14 EGO52768.1 - 0.033 11.9 9.4 0.049 11.3 6.5 1.3 1 0 0 1 1 1 0 Myosin tail Prominin PF05478.6 EGO52768.1 - 0.036 11.6 7.6 0.0065 14.0 2.0 1.8 1 1 1 2 2 2 0 Prominin Prefoldin_2 PF01920.15 EGO52768.1 - 0.036 13.8 7.3 0.42 10.3 1.2 3.2 3 0 0 3 3 3 0 Prefoldin subunit Filament PF00038.16 EGO52768.1 - 0.045 13.2 10.8 0.64 9.4 0.8 2.1 1 1 0 2 2 2 0 Intermediate filament protein Nup54 PF13874.1 EGO52768.1 - 0.077 12.6 11.7 0.018 14.6 3.5 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 IncA PF04156.9 EGO52768.1 - 0.094 12.3 16.9 0.14 11.7 4.2 2.2 1 1 1 2 2 2 0 IncA protein Ribosomal_L6e PF01159.14 EGO52768.1 - 0.095 12.9 0.8 0.57 10.4 0.0 2.5 2 1 1 3 3 3 0 Ribosomal protein L6e Rootletin PF15035.1 EGO52768.1 - 0.11 12.4 13.9 0.14 12.0 8.0 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Prefoldin PF02996.12 EGO52768.1 - 0.13 11.8 6.9 0.19 11.3 0.5 2.9 2 1 1 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.7 EGO52768.1 - 0.15 11.8 9.5 0.1 12.4 1.4 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.1 EGO52768.1 - 0.18 10.9 12.2 0.46 9.6 2.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.1 EGO52768.1 - 0.18 11.7 6.8 4.3 7.3 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) WXG100 PF06013.7 EGO52768.1 - 0.19 11.7 6.6 3 7.9 0.2 3.3 1 1 2 4 4 4 0 Proteins of 100 residues with WXG Tweety PF04906.8 EGO52768.1 - 0.23 9.8 3.6 0.14 10.5 0.5 1.8 1 1 1 2 2 2 0 Tweety AAA_13 PF13166.1 EGO52768.1 - 0.24 9.8 9.1 0.67 8.3 6.3 1.5 1 1 0 1 1 1 0 AAA domain Cortex-I_coil PF09304.5 EGO52768.1 - 0.35 10.9 10.8 2.6 8.1 2.1 2.9 1 1 0 2 2 2 0 Cortexillin I, coiled coil FlgN PF05130.7 EGO52768.1 - 0.61 10.3 15.0 1.5 9.0 4.5 2.5 1 1 0 2 2 2 0 FlgN protein HrpB7 PF09486.5 EGO52768.1 - 0.64 9.9 6.2 7.5 6.4 0.3 2.5 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4484 PF14831.1 EGO52768.1 - 1.2 9.2 4.0 1.7 8.7 2.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) F_actin_bind PF08919.5 EGO52768.1 - 1.4 8.6 5.7 9 6.0 0.2 3.1 3 0 0 3 3 3 0 F-actin binding Spc24 PF08286.6 EGO52768.1 - 1.6 8.4 11.7 2.9 7.6 1.7 3.0 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Jnk-SapK_ap_N PF09744.4 EGO52768.1 - 1.7 8.6 8.0 5.8 6.8 0.3 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4404 PF14357.1 EGO52768.1 - 2.1 8.8 13.6 1.7 9.0 2.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) EAP30 PF04157.11 EGO52768.1 - 2.1 7.4 8.8 0.49 9.5 0.2 2.5 2 1 0 2 2 2 0 EAP30/Vps36 family DUF342 PF03961.8 EGO52768.1 - 2.1 6.6 8.4 1.7 7.0 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 EGO52768.1 - 2.6 8.1 11.6 8.9 6.4 1.9 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TBPIP PF07106.8 EGO52768.1 - 2.6 7.5 10.7 0.78 9.2 2.5 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin_1 PF12718.2 EGO52768.1 - 3.7 7.3 8.6 8.9 6.1 1.5 2.3 1 1 0 2 2 2 0 Tropomyosin like APG6 PF04111.7 EGO52768.1 - 3.9 6.4 14.3 0.77 8.7 3.8 2.7 2 1 1 3 3 3 0 Autophagy protein Apg6 FliJ PF02050.11 EGO52768.1 - 4 7.5 15.9 2.7 8.0 1.1 2.6 1 1 1 2 2 2 0 Flagellar FliJ protein DUF972 PF06156.8 EGO52768.1 - 4.1 7.7 8.5 4.1 7.7 0.9 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Glyco_transf_34 PF05637.7 EGO52769.1 - 4.8e-65 219.4 0.7 6.3e-65 219.0 0.5 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF3328 PF11807.3 EGO52772.1 - 0.056 13.1 0.1 0.27 10.8 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) Herpes_US9 PF06072.6 EGO52772.1 - 0.22 11.3 4.0 0.11 12.3 0.7 2.0 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Peptidase_M22 PF00814.20 EGO52773.1 - 3.2e-49 167.8 0.8 7.7e-26 91.1 0.2 3.3 2 1 0 2 2 2 2 Glycoprotease family FGGY_C PF02782.11 EGO52773.1 - 0.0056 16.3 0.1 0.32 10.5 0.0 2.8 4 0 0 4 4 4 1 FGGY family of carbohydrate kinases, C-terminal domain Proteasome PF00227.21 EGO52774.1 - 2.1e-49 167.4 0.2 2.5e-49 167.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF3222 PF11519.3 EGO52774.1 - 0.076 12.9 0.3 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) DUF554 PF04474.7 EGO52774.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) PTP_N PF12453.3 EGO52775.1 - 0.087 12.4 0.2 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal DUF1752 PF08550.5 EGO52776.1 - 1.1e-08 34.5 2.6 2e-08 33.6 1.8 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF4611 PF15387.1 EGO52776.1 - 0.12 12.4 3.1 2 8.6 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Met_10 PF02475.11 EGO52778.1 - 1.5e-82 276.0 0.0 2.1e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Prenyltransf PF01255.14 EGO52779.1 - 2.1e-06 27.0 0.0 1.6e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Sec10 PF07393.6 EGO52780.1 - 1e-225 751.1 0.0 1.3e-225 750.9 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF4554 PF15091.1 EGO52780.1 - 0.0032 16.2 0.0 0.0054 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4554) PAP_central PF04928.12 EGO52780.1 - 0.092 11.5 0.1 0.24 10.1 0.0 1.6 1 0 0 1 1 1 0 Poly(A) polymerase central domain HopJ PF08888.6 EGO52780.1 - 0.1 12.5 0.5 12 5.9 0.0 2.5 2 0 0 2 2 2 0 HopJ type III effector protein DUF2607 PF10795.4 EGO52781.1 - 0.63 9.9 3.5 1.4 8.8 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) HLH PF00010.21 EGO52782.1 - 2e-18 65.7 0.0 4.3e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tropomyosin PF00261.15 EGO52782.1 - 0.0046 16.0 0.9 0.0089 15.1 0.6 1.4 1 0 0 1 1 1 1 Tropomyosin DUF912 PF06024.7 EGO52783.1 - 0.0042 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Kelch_4 PF13418.1 EGO52783.1 - 0.0073 16.0 1.8 0.29 10.9 0.0 3.9 5 0 0 5 5 5 1 Galactose oxidase, central domain DUF1183 PF06682.7 EGO52783.1 - 0.0074 15.9 0.4 0.0074 15.9 0.3 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1183) TMEM154 PF15102.1 EGO52783.1 - 0.81 9.3 11.1 7 6.3 7.7 2.2 1 1 0 1 1 1 0 TMEM154 protein family TAP_C PF03943.8 EGO52784.1 - 3.3e-09 36.0 0.1 6.3e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EGO52784.1 - 7.3e-07 28.6 10.2 1.1e-05 24.9 1.0 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 EGO52784.1 - 4.2e-05 23.8 0.0 0.00045 20.5 0.0 2.5 2 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.1 EGO52784.1 - 0.0012 18.5 6.8 0.0085 15.8 0.3 2.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EGO52784.1 - 0.0036 17.1 3.8 2 8.7 0.1 3.5 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EGO52784.1 - 0.073 13.3 2.6 11 6.6 0.2 3.5 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 EGO52784.1 - 0.096 12.8 2.7 19 5.7 0.3 3.4 3 0 0 3 3 3 0 Leucine Rich repeat DEAD PF00270.24 EGO52786.1 - 2.1e-20 72.8 0.0 6.7e-20 71.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO52786.1 - 3.8e-20 71.5 0.1 9.2e-20 70.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO52786.1 - 1.2e-19 70.8 0.0 2.8e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EGO52786.1 - 0.0022 18.1 0.0 0.0074 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain MSC PF09402.5 EGO52787.1 - 1e-107 359.7 0.0 1.4e-107 359.2 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EGO52787.1 - 4.3e-17 61.3 0.1 7.7e-17 60.5 0.0 1.4 1 0 0 1 1 1 1 HeH/LEM domain DUF3350 PF11830.3 EGO52787.1 - 0.0092 15.9 1.6 6.4 6.8 0.5 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3350) Thymopoietin PF08198.6 EGO52787.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Thymopoietin protein HisG PF01634.13 EGO52789.1 - 1.6e-48 164.3 0.2 6e-38 129.9 0.0 2.4 2 0 0 2 2 2 2 ATP phosphoribosyltransferase HisG_C PF08029.6 EGO52789.1 - 2.6e-28 97.7 1.0 4.5e-28 96.9 0.2 1.8 2 0 0 2 2 2 1 HisG, C-terminal domain MFS_2 PF13347.1 EGO52790.1 - 2e-13 49.5 14.4 2e-13 49.5 10.0 2.5 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.2 EGO52790.1 - 0.033 13.9 3.5 0.13 12.0 0.0 3.6 3 1 1 4 4 4 0 MFS_1 like family DUF1228 PF06779.9 EGO52790.1 - 0.39 10.7 5.0 0.9 9.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Sel1 PF08238.7 EGO52791.1 - 5.8e-37 125.2 28.7 3.6e-05 24.2 0.1 7.5 7 0 0 7 7 7 7 Sel1 repeat Chitin_synth_2 PF03142.10 EGO52792.1 - 4.6e-293 972.4 0.4 6.1e-293 972.0 0.0 1.3 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EGO52792.1 - 2.7e-18 66.3 2.2 1.2e-17 64.2 1.5 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 EGO52792.1 - 5.3e-15 54.9 0.3 4e-11 42.5 0.1 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 EGO52792.1 - 1.2e-14 54.7 0.0 4.2e-13 49.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGO52792.1 - 7.3e-05 22.1 0.0 0.00039 19.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EGO52792.1 - 0.019 14.6 0.0 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 WD40 PF00400.27 EGO52793.1 - 2.9e-06 26.9 0.7 3.8e-05 23.3 0.3 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF2415 PF10313.4 EGO52793.1 - 0.023 14.3 0.2 0.067 12.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Glyco_hydro_17 PF00332.13 EGO52794.1 - 0.041 12.9 0.1 0.13 11.3 0.1 1.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 RNB PF00773.14 EGO52796.1 - 1.5e-67 228.2 0.0 2.3e-67 227.6 0.0 1.3 1 0 0 1 1 1 1 RNB domain Ada3 PF10198.4 EGO52797.1 - 0.31 10.7 7.0 0.043 13.5 1.7 1.9 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 GET2 PF08690.5 EGO52797.1 - 3.6 6.7 7.9 8.6 5.5 5.5 1.6 1 0 0 1 1 1 0 GET complex subunit GET2 Myb_DNA-bind_6 PF13921.1 EGO52798.1 - 3.2e-06 27.1 0.1 7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGO52798.1 - 0.0012 18.8 0.1 0.0027 17.7 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF912 PF06024.7 EGO52798.1 - 0.34 11.0 5.2 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Hid1 PF12722.2 EGO52798.1 - 4.2 4.9 6.0 5.4 4.5 4.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3328 PF11807.3 EGO52799.1 - 0.0084 15.8 0.0 0.0096 15.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ribonuc_L-PSP PF01042.16 EGO52800.1 - 2.6e-40 136.9 0.0 2.8e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF3972 PF13118.1 EGO52800.1 - 0.1 12.7 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) PMT PF02366.13 EGO52801.1 - 2.2e-81 272.8 14.8 2.2e-81 272.8 10.3 1.5 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EGO52801.1 - 5e-20 71.8 0.4 1.4e-16 60.5 0.0 2.2 1 1 1 2 2 2 2 MIR domain zf-C2H2 PF00096.21 EGO52802.1 - 0.015 15.6 2.6 0.015 15.6 1.8 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO52802.1 - 1.4 9.4 18.9 0.098 13.0 1.3 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger adh_short PF00106.20 EGO52803.1 - 9.3e-26 90.7 0.0 1.2e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO52803.1 - 4.5e-25 88.8 0.0 5.8e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO52803.1 - 1.1e-10 41.5 0.0 1.5e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EGO52803.1 - 9e-05 22.1 0.1 0.0002 21.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EGO52803.1 - 0.00016 21.2 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EGO52803.1 - 0.038 13.1 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ABC_tran PF00005.22 EGO52804.1 - 4.8e-50 169.4 0.0 1.5e-17 64.2 0.0 3.4 3 0 0 3 3 3 3 ABC transporter ABC_membrane PF00664.18 EGO52804.1 - 1.8e-19 70.2 18.8 5.9e-17 61.9 11.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EGO52804.1 - 9.9e-10 38.0 0.0 0.0016 17.7 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EGO52804.1 - 5.4e-08 32.4 0.6 0.003 16.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 EGO52804.1 - 2.4e-07 30.9 0.0 0.2 11.6 0.0 4.2 3 1 1 4 4 4 1 AAA domain AAA_29 PF13555.1 EGO52804.1 - 2.3e-06 27.0 1.1 0.073 12.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 EGO52804.1 - 2.5e-05 23.8 0.1 3.9 6.8 0.0 3.3 3 0 0 3 3 3 2 AAA-like domain AAA_16 PF13191.1 EGO52804.1 - 7.4e-05 22.8 1.0 0.18 11.7 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 EGO52804.1 - 0.0001 22.7 0.2 0.016 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGO52804.1 - 0.0001 21.4 0.1 0.49 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGO52804.1 - 0.00013 22.1 0.1 4.3 7.4 0.0 3.8 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 EGO52804.1 - 0.00017 21.5 0.1 0.3 11.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 EGO52804.1 - 0.00018 22.3 0.1 0.021 15.6 0.0 3.3 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 EGO52804.1 - 0.00038 20.3 3.9 0.043 13.6 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_18 PF13238.1 EGO52804.1 - 0.00088 19.5 2.7 1.4 9.2 0.0 4.1 4 1 1 5 5 4 1 AAA domain Zeta_toxin PF06414.7 EGO52804.1 - 0.0019 17.3 0.5 0.88 8.6 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin Miro PF08477.8 EGO52804.1 - 0.004 17.6 0.1 3.7 8.0 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 EGO52804.1 - 0.0071 16.0 0.6 1.9 8.1 0.2 2.5 2 0 0 2 2 2 1 NACHT domain T2SE PF00437.15 EGO52804.1 - 0.011 14.7 0.1 0.069 12.0 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein ArgK PF03308.11 EGO52804.1 - 0.014 14.1 0.3 0.037 12.8 0.0 1.7 2 0 0 2 2 2 0 ArgK protein FtsK_SpoIIIE PF01580.13 EGO52804.1 - 0.026 13.9 0.1 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EGO52804.1 - 0.053 13.1 0.1 5.7 6.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.4 EGO52804.1 - 0.062 12.2 0.6 2.6 6.9 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 EGO52804.1 - 0.081 12.7 0.9 2.7 7.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EGO52804.1 - 0.095 12.8 0.0 13 6.0 0.0 2.9 3 0 0 3 3 2 0 RNA helicase MobB PF03205.9 EGO52804.1 - 0.1 12.2 0.4 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 EGO52804.1 - 0.11 12.4 0.1 2 8.3 0.0 2.9 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 EGO52804.1 - 0.11 11.3 1.3 0.94 8.2 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain ATP-synt_ab PF00006.20 EGO52804.1 - 0.13 11.7 0.0 0.56 9.6 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.21 EGO52804.1 - 0.18 11.2 0.0 8.6 5.7 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EGO52804.1 - 0.19 11.4 1.0 4.5 6.9 0.0 3.2 4 0 0 4 4 3 0 NTPase AAA PF00004.24 EGO52804.1 - 0.2 11.8 0.1 79 3.4 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Pro_isomerase PF00160.16 EGO52805.1 - 9.2e-51 172.1 0.2 2.1e-50 170.9 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EGO52805.1 - 1.6e-14 53.0 0.2 2.6e-07 30.2 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Far-17a_AIG1 PF04750.9 EGO52806.1 - 7.6e-57 191.7 14.1 8.7e-57 191.5 9.8 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF2374 PF09574.5 EGO52806.1 - 0.024 14.2 0.4 7.1 6.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) DAHP_synth_1 PF00793.15 EGO52808.1 - 6.3e-98 326.7 0.0 7.7e-98 326.4 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family Mu-like_Pro PF10123.4 EGO52808.1 - 0.0096 15.4 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 1 Mu-like prophage I protein Cytochrom_C1 PF02167.10 EGO52809.1 - 7.8e-82 274.1 0.0 9.5e-82 273.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EGO52809.1 - 0.0059 16.7 0.0 0.013 15.6 0.0 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EGO52809.1 - 0.098 13.4 0.0 0.41 11.5 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c HhH-GPD PF00730.20 EGO52810.1 - 4.2e-09 36.6 0.0 8.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ssl1 PF04056.9 EGO52810.1 - 0.22 11.0 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Ssl1-like CVNH PF08881.5 EGO52811.1 - 2.9e-10 40.3 0.0 4.6e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 CVNH domain Nup84_Nup100 PF04121.8 EGO52812.1 - 4.6e-68 229.5 0.0 4.6e-67 226.2 0.0 2.4 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 DUF1903 PF08991.5 EGO52813.1 - 8.7e-26 89.8 7.3 1e-25 89.6 5.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EGO52813.1 - 0.00044 20.1 6.2 0.00076 19.3 4.3 1.5 1 0 0 1 1 1 1 CHCH domain NDUFB10 PF10249.4 EGO52813.1 - 0.084 13.0 1.1 0.099 12.7 0.8 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 DUF4333 PF14230.1 EGO52813.1 - 0.096 12.6 0.2 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4333) Cmc1 PF08583.5 EGO52813.1 - 0.45 10.3 7.0 0.15 11.8 1.3 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Rad60-SLD PF11976.3 EGO52814.1 - 1.1e-18 66.6 0.1 1.4e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGO52814.1 - 2.7e-07 29.9 0.1 3.2e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family HH_signal PF01085.13 EGO52814.1 - 0.011 15.3 0.0 0.011 15.3 0.0 1.0 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain LIM PF00412.17 EGO52816.1 - 1.5e-25 88.9 20.8 1.8e-08 34.3 0.6 3.5 3 0 0 3 3 3 3 LIM domain Ycf1 PF05758.7 EGO52816.1 - 0.012 13.3 0.8 0.016 12.9 0.5 1.1 1 0 0 1 1 1 0 Ycf1 AAA_23 PF13476.1 EGO52816.1 - 0.56 10.4 9.1 0.9 9.8 6.3 1.3 1 0 0 1 1 1 0 AAA domain Hid1 PF12722.2 EGO52816.1 - 0.82 7.2 9.6 1.3 6.5 6.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Plasmodium_Vir PF05795.6 EGO52816.1 - 1.7 7.7 3.5 3.8 6.6 2.4 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF-3_zeta PF05091.7 EGO52816.1 - 6.2 5.3 17.6 9.8 4.6 12.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MFS_1 PF07690.11 EGO52817.1 - 3e-22 78.8 53.9 3e-22 78.8 37.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily FAP PF07174.6 EGO52817.1 - 0.047 12.9 0.2 0.063 12.5 0.1 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Ligase_CoA PF00549.14 EGO52818.1 - 8.8e-35 119.5 1.8 1.3e-19 70.3 0.3 2.3 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 EGO52818.1 - 5.9e-16 58.7 1.1 2.1e-15 56.9 0.1 2.5 3 0 0 3 3 3 1 CoA binding domain Succ_CoA_lig PF13607.1 EGO52818.1 - 6.7e-06 25.7 0.0 0.0015 18.1 0.0 2.6 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CHCH PF06747.8 EGO52819.1 - 0.00057 19.7 0.4 0.00097 18.9 0.2 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EGO52819.1 - 0.0062 16.5 2.2 0.1 12.6 1.8 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.11 EGO52819.1 - 0.11 12.4 1.3 0.32 10.9 0.9 1.7 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.8 EGO52819.1 - 0.36 10.8 3.0 14 5.7 0.1 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Dynamin_M PF01031.15 EGO52821.1 - 2.8e-114 380.8 0.0 6.2e-114 379.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EGO52821.1 - 4.5e-55 186.0 1.8 5e-55 185.8 0.0 2.0 3 0 0 3 3 3 1 Dynamin family GED PF02212.13 EGO52821.1 - 6.5e-31 106.0 2.8 6.5e-31 106.0 2.0 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGO52821.1 - 0.00055 19.8 0.0 0.0021 18.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGO52821.1 - 0.011 16.1 0.0 0.056 13.9 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein F-box PF00646.28 EGO52822.1 - 2.3e-05 23.9 0.3 5.4e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGO52822.1 - 0.058 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 F-box-like Apolipo_F PF15148.1 EGO52823.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein F Alpha-amylase PF00128.19 EGO52824.1 - 6.1e-56 190.1 0.2 2.4e-53 181.6 0.2 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.14 EGO52824.1 - 1.3e-22 79.2 0.2 2.9e-22 78.0 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.6 EGO52824.1 - 6.7e-15 54.9 1.2 1.5e-14 53.8 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Fungal_trans PF04082.13 EGO52825.1 - 6e-18 64.6 1.4 9.3e-18 64.0 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glutaredoxin PF00462.19 EGO52826.1 - 8.4e-19 67.3 0.0 3.3e-17 62.2 0.0 2.4 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EGO52826.1 - 4.1e-14 52.1 0.0 8.5e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGO52826.1 - 0.0031 17.5 0.0 0.3 11.2 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.1 EGO52826.1 - 0.076 12.8 0.0 0.61 9.9 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain TrbC_Ftype PF09673.5 EGO52826.1 - 0.1 12.2 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein SH3_9 PF14604.1 EGO52829.1 - 1e-30 105.0 3.0 1.1e-14 53.7 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EGO52829.1 - 2.1e-25 87.8 3.9 3.1e-12 45.6 0.3 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EGO52829.1 - 3.6e-17 61.5 0.0 6.2e-08 32.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 EGO52829.1 - 7e-11 42.1 0.0 1.9e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein DUF2663 PF10864.3 EGO52830.1 - 0.056 13.6 0.1 0.06 13.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) Ribonuc_red_lgN PF00317.16 EGO52830.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain Mod_r PF07200.8 EGO52831.1 - 9e-08 32.1 5.6 1.3e-07 31.6 3.5 1.5 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein F-box PF00646.28 EGO52832.1 - 1.9e-05 24.1 0.3 5.6e-05 22.6 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGO52832.1 - 0.009 15.7 0.3 0.009 15.7 0.2 2.8 3 0 0 3 3 3 1 F-box-like Cobl PF09469.5 EGO52832.1 - 0.42 10.6 2.5 0.8 9.7 0.1 2.4 3 0 0 3 3 3 0 Cordon-bleu ubiquitin-like domain V-ATPase_C PF03223.10 EGO52834.1 - 4.5e-115 384.4 0.1 5.1e-115 384.3 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Cauli_AT PF03233.8 EGO52834.1 - 0.077 12.6 0.7 0.14 11.8 0.5 1.4 1 0 0 1 1 1 0 Aphid transmission protein APS_kinase PF01583.15 EGO52835.1 - 1.4e-70 235.9 0.0 1.8e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EGO52835.1 - 1e-06 28.6 0.0 1.8e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO52835.1 - 2.3e-06 28.4 0.0 3.1e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO52835.1 - 4.5e-05 23.7 0.0 8.3e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGO52835.1 - 0.00047 19.4 0.0 0.0007 18.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 EGO52835.1 - 0.039 13.4 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_26 PF13500.1 EGO52835.1 - 0.046 13.3 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGO52835.1 - 0.069 13.1 0.2 0.13 12.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain 4HBT PF03061.17 EGO52836.1 - 5.5e-10 39.2 0.0 9.6e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily CBF PF03914.12 EGO52837.1 - 2.2e-47 160.5 0.5 2.2e-47 160.5 0.3 2.9 3 0 0 3 3 3 1 CBF/Mak21 family DUF2178 PF09946.4 EGO52837.1 - 0.21 11.3 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) tRNA-synt_2b PF00587.20 EGO52838.1 - 2e-35 121.8 0.0 2.9e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGO52838.1 - 3.8e-08 33.1 0.0 1.1e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EGO52838.1 - 0.064 12.0 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) RVT_1 PF00078.22 EGO52839.1 - 0.0077 15.5 0.1 0.0088 15.4 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3051 PF11252.3 EGO52839.1 - 0.1 12.0 0.3 0.11 11.9 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3051) NeuB PF03102.9 EGO52842.1 - 0.14 11.2 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 NeuB family CRT-like PF08627.5 EGO52847.1 - 0.11 12.4 1.3 0.12 12.2 0.9 1.2 1 0 0 1 1 1 0 CRT-like UCH PF00443.24 EGO52850.1 - 5e-39 134.0 0.0 6.6e-33 113.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO52850.1 - 9.4e-13 48.2 0.0 1e-09 38.3 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Oxysterol_BP PF01237.13 EGO52852.1 - 1.1e-88 297.1 0.0 1.3e-88 296.8 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein GFO_IDH_MocA PF01408.17 EGO52853.1 - 2e-14 54.1 0.0 4.7e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGO52853.1 - 3.9e-05 23.4 0.0 9.7e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Ilar_coat PF01787.11 EGO52853.1 - 0.058 12.9 0.1 0.45 10.0 0.1 2.0 2 0 0 2 2 2 0 Ilarvirus coat protein GARS_N PF02844.10 EGO52853.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain PGM_PMM_I PF02878.11 EGO52854.1 - 1.3e-33 115.4 0.0 1.9e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EGO52854.1 - 2e-25 89.0 0.0 4.8e-25 87.7 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EGO52854.1 - 8.2e-16 58.2 0.0 1.7e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EGO52854.1 - 3.6e-08 33.2 0.0 7.9e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain HMG_box PF00505.14 EGO52857.1 - 1.2e-25 89.5 1.1 2e-25 88.8 0.8 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO52857.1 - 8.2e-19 67.7 2.2 8.2e-19 67.7 1.5 1.6 1 1 1 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 EGO52857.1 - 0.0011 18.6 1.3 0.0024 17.6 0.9 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 EGO52857.1 - 0.021 15.0 0.8 0.061 13.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) DEADboxA PF12343.3 EGO52857.1 - 0.12 12.6 2.3 0.21 11.8 0.2 2.0 1 1 1 2 2 2 0 Cold shock protein DEAD box A CENP-H PF05837.7 EGO52858.1 - 1.9e-29 101.9 0.0 3.2e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Centromere protein H (CENP-H) ATG11 PF10377.4 EGO52859.1 - 1.4e-42 144.6 2.1 3.7e-42 143.2 0.1 2.7 2 0 0 2 2 2 1 Autophagy-related protein 11 Spectrin PF00435.16 EGO52859.1 - 0.0013 19.0 4.3 0.0013 19.0 3.0 6.7 7 0 0 7 7 7 2 Spectrin repeat Reo_sigmaC PF04582.7 EGO52859.1 - 1.2 8.2 24.4 0.47 9.5 0.2 5.5 4 2 1 6 6 6 0 Reovirus sigma C capsid protein Ribosomal_L9_N PF01281.14 EGO52860.1 - 4.5e-08 32.2 0.0 7.8e-08 31.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 EGO52860.1 - 0.091 12.8 0.0 0.41 10.7 0.0 2.0 1 1 0 1 1 1 0 Ribosomal protein L9, C-terminal domain AATase PF07247.7 EGO52861.1 - 1.3e-21 76.7 0.0 1.6e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EGO52861.1 - 0.037 12.8 0.4 0.18 10.6 0.3 2.0 1 1 0 1 1 1 0 Condensation domain Herpes_UL33 PF03581.8 EGO52863.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus UL33-like protein LSM PF01423.17 EGO52864.1 - 2.6e-19 68.5 0.1 3e-19 68.3 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGO52864.1 - 0.00073 19.4 0.1 0.00082 19.2 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain HSP20 PF00011.16 EGO52865.1 - 2.6e-18 65.7 0.0 2.7e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family DUF4432 PF14486.1 EGO52865.1 - 0.011 14.3 0.0 0.024 13.2 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4432) PEP-utilizers PF00391.18 EGO52865.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain YTH PF04146.10 EGO52866.1 - 2.7e-56 189.0 0.0 4.2e-56 188.4 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain Proteasome PF00227.21 EGO52867.1 - 5.8e-31 107.2 0.2 2.3e-30 105.3 0.2 2.0 1 1 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.22 EGO52868.1 - 2.2e-40 138.5 0.0 8e-40 136.7 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EGO52868.1 - 7.5e-23 80.6 0.0 1.9e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Sad1_UNC PF07738.8 EGO52868.1 - 0.15 11.8 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Cation_efflux PF01545.16 EGO52869.1 - 3.2e-31 108.4 11.9 3.8e-31 108.2 8.3 1.1 1 0 0 1 1 1 1 Cation efflux family DMRL_synthase PF00885.14 EGO52871.1 - 4e-47 159.5 0.0 4.7e-29 100.9 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase HATPase_c_3 PF13589.1 EGO52873.1 - 3.8e-14 52.5 0.0 7.3e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGO52873.1 - 8.3e-10 38.3 0.0 2.4e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EGO52873.1 - 1.1e-05 24.8 0.0 2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain TRP PF06011.7 EGO52874.1 - 1.5e-92 310.4 20.6 9.3e-92 307.8 14.3 1.9 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGO52874.1 - 4.5e-31 107.7 0.5 8.2e-31 106.9 0.0 1.6 2 0 0 2 2 2 1 ML-like domain WD40 PF00400.27 EGO52875.1 - 2.4e-10 39.8 3.2 0.12 12.3 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat RNA_pol_Rpb4 PF03874.11 EGO52876.1 - 1.5e-28 99.1 2.9 4.6e-28 97.5 2.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb4 Rax2 PF12768.2 EGO52877.1 - 0.05 12.8 0.1 0.11 11.7 0.0 1.4 1 1 0 1 1 1 0 Cortical protein marker for cell polarity SOG2 PF10428.4 EGO52877.1 - 0.13 10.8 9.0 0.19 10.3 6.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Tmemb_cc2 PF10267.4 EGO52877.1 - 5 5.6 8.3 1.1 7.7 1.6 2.1 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein CPL PF08144.6 EGO52878.1 - 5.7e-19 68.4 0.0 2.2e-18 66.5 0.0 2.1 1 0 0 1 1 1 1 CPL (NUC119) domain RWD PF05773.17 EGO52879.1 - 1.2e-24 86.4 0.2 2e-24 85.6 0.2 1.4 1 0 0 1 1 1 1 RWD domain TPR_12 PF13424.1 EGO52880.1 - 3.3e-09 36.5 3.8 0.0011 18.8 0.5 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGO52880.1 - 3.1e-07 29.9 0.4 0.061 12.9 0.6 3.3 2 1 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 EGO52880.1 - 3.6e-07 30.4 5.7 0.00012 22.2 0.1 3.9 3 1 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO52880.1 - 2e-05 24.0 0.5 0.0036 16.9 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGO52880.1 - 3.3e-05 24.1 7.9 0.85 10.4 0.0 5.7 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO52880.1 - 7.5e-05 23.2 10.5 0.053 14.2 0.4 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGO52880.1 - 0.00075 18.9 0.0 0.011 15.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGO52880.1 - 0.00076 19.2 7.8 0.37 10.8 0.0 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGO52880.1 - 0.011 15.5 4.5 0.058 13.1 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGO52880.1 - 0.025 14.4 1.1 8.6 6.4 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGO52880.1 - 0.15 12.5 3.5 0.79 10.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGO52880.1 - 1.5 9.4 9.2 39 4.9 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat CFEM PF05730.6 EGO52881.1 - 0.0043 16.8 5.1 0.0073 16.1 3.5 1.4 1 0 0 1 1 1 1 CFEM domain MCPVI PF02993.9 EGO52881.1 - 4.5 7.3 10.6 6.2 6.9 7.3 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Cyclotide PF03784.8 EGO52881.1 - 5.8 6.8 12.1 0.11 12.4 3.7 1.6 2 0 0 2 2 2 0 Cyclotide family MutS_V PF00488.16 EGO52882.1 - 7.1e-53 179.4 0.0 1.3e-52 178.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGO52882.1 - 0.041 13.6 0.1 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 MutS domain III AAA_29 PF13555.1 EGO52882.1 - 0.042 13.3 0.0 0.68 9.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain DAP3 PF10236.4 EGO52882.1 - 0.2 10.5 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MMgT PF10270.4 EGO52884.1 - 1.5e-35 121.8 0.0 1.7e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter HMG_box PF00505.14 EGO52885.1 - 5.9e-10 39.2 1.1 1.6e-09 37.9 0.8 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO52885.1 - 0.015 15.6 0.8 0.027 14.8 0.6 1.5 1 0 0 1 1 1 0 HMG-box domain MAT_Alpha1 PF04769.7 EGO52885.1 - 0.073 12.3 1.8 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 Zip PF02535.17 EGO52885.1 - 0.62 9.0 5.5 0.14 11.1 1.4 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter EGF PF00008.22 EGO52886.1 - 0.11 12.4 2.0 4.5 7.3 0.0 2.3 2 0 0 2 2 2 0 EGF-like domain PHD PF00628.24 EGO52887.1 - 1.7e-08 33.9 9.0 3.7e-08 32.9 6.3 1.6 1 0 0 1 1 1 1 PHD-finger PHF5 PF03660.9 EGO52887.1 - 0.029 14.4 2.4 0.056 13.5 1.7 1.4 1 0 0 1 1 1 0 PHF5-like protein PHD_2 PF13831.1 EGO52887.1 - 0.15 11.4 5.6 0.31 10.3 3.9 1.5 1 0 0 1 1 1 0 PHD-finger Ion_trans PF00520.26 EGO52888.1 - 1.1e-89 299.0 72.3 1.2e-28 99.7 6.3 5.6 5 1 1 6 6 6 5 Ion transport protein EF-hand_1 PF00036.27 EGO52888.1 - 0.08 12.2 0.0 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 EF hand JSRP PF15312.1 EGO52888.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein Trs65 PF12735.2 EGO52889.1 - 0.16 11.2 3.7 0.2 10.9 2.6 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 Cyclin_N PF00134.18 EGO52892.1 - 1.6e-44 150.5 0.0 9.6e-44 148.0 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGO52892.1 - 2.9e-33 114.2 0.0 6.3e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_L2_C PF03947.13 EGO52893.1 - 1.4e-44 151.0 4.1 2.2e-44 150.3 1.2 2.4 2 1 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EGO52893.1 - 3.1e-27 94.3 0.2 6.2e-27 93.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PAP2 PF01569.16 EGO52894.1 - 5.6e-20 71.3 1.5 5.6e-20 71.3 1.1 2.4 2 1 0 2 2 2 1 PAP2 superfamily CK_II_beta PF01214.13 EGO52895.1 - 4.6e-74 247.9 0.7 4.6e-74 247.9 0.5 1.4 2 0 0 2 2 2 1 Casein kinase II regulatory subunit DHHW PF14286.1 EGO52895.1 - 0.0012 18.2 0.1 0.0018 17.6 0.1 1.2 1 0 0 1 1 1 1 DHHW protein Myc_N PF01056.13 EGO52895.1 - 0.06 12.5 3.9 0.085 12.0 2.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF1660 PF07874.6 EGO52895.1 - 0.075 13.3 0.0 17 5.8 0.0 2.8 2 0 0 2 2 2 0 Prophage protein (DUF1660) RXT2_N PF08595.6 EGO52895.1 - 0.12 12.1 5.0 0.26 11.0 3.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2890 PF11081.3 EGO52895.1 - 0.16 12.0 8.4 0.26 11.3 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF3381 PF11861.3 EGO52895.1 - 0.41 10.1 10.6 0.63 9.5 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Nucleoplasmin PF03066.10 EGO52895.1 - 0.88 9.0 10.8 1.5 8.3 7.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 EGO52895.1 - 1.2 6.9 10.3 1.6 6.5 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 EGO52895.1 - 1.6 6.5 3.7 2 6.1 2.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 EGO52895.1 - 1.7 7.0 10.5 2.3 6.6 7.3 1.1 1 0 0 1 1 1 0 Daxx Family CAF1-p150_C2 PF15539.1 EGO52895.1 - 2 7.4 4.4 3 6.8 3.0 1.2 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Paf1 PF03985.8 EGO52895.1 - 5.8 5.5 12.4 8 5.0 8.6 1.1 1 0 0 1 1 1 0 Paf1 RIC1 PF07064.8 EGO52896.1 - 2.1e-91 305.9 0.0 2.8e-91 305.5 0.0 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 EGO52896.1 - 1.4e-06 27.9 0.5 0.37 10.7 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40 PF00400.27 EGO52897.1 - 2.4e-29 100.0 11.2 2.8e-06 26.9 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EGO52897.1 - 3.7e-06 25.3 1.8 0.00028 19.1 0.1 2.9 2 1 0 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EGO52897.1 - 4e-06 26.6 0.2 0.057 13.1 0.0 3.3 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGO52897.1 - 0.0022 16.3 0.0 1.1 7.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain DUF1513 PF07433.6 EGO52897.1 - 0.014 14.3 0.2 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Coatomer_WDAD PF04053.9 EGO52897.1 - 0.2 10.4 0.0 0.39 9.4 0.0 1.5 2 0 0 2 2 2 0 Coatomer WD associated region Fungal_trans PF04082.13 EGO52898.1 - 4.7e-23 81.3 0.5 1.8e-22 79.4 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO52898.1 - 5.7e-09 35.7 12.5 6.3e-09 35.6 7.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DMP1 PF07263.6 EGO52899.1 - 0.15 10.7 2.6 0.17 10.6 1.8 1.0 1 0 0 1 1 1 0 Dentin matrix protein 1 (DMP1) Pkinase PF00069.20 EGO52900.1 - 9.4e-65 218.3 0.0 1.3e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO52900.1 - 3.2e-29 101.7 0.0 6e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EGO52900.1 - 1.7e-10 40.8 0.0 4.4e-08 33.1 0.0 2.9 3 0 0 3 3 3 1 FHA domain Kinase-like PF14531.1 EGO52900.1 - 6.3e-05 22.0 0.0 0.00016 20.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like DUF3868 PF12984.2 EGO52900.1 - 0.067 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) YrbL-PhoP_reg PF10707.4 EGO52900.1 - 0.23 10.7 0.0 0.48 9.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EGO52900.1 - 0.27 10.2 0.0 0.46 9.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.24 EGO52901.1 - 0.025 14.7 0.2 0.3 11.3 0.0 2.8 3 0 0 3 3 3 0 PH domain SpoIIE PF07228.7 EGO52902.1 - 0.00015 21.5 0.0 0.0014 18.3 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EGO52902.1 - 0.038 13.4 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 Protein phosphatase 2C Fcf1 PF04900.7 EGO52903.1 - 3.4e-22 78.4 0.1 8.5e-22 77.1 0.1 1.7 1 0 0 1 1 1 1 Fcf1 YL1 PF05764.8 EGO52903.1 - 0.22 11.0 27.3 0.35 10.4 19.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Glypican PF01153.14 EGO52903.1 - 0.76 8.3 6.8 1 7.8 4.7 1.2 1 0 0 1 1 1 0 Glypican Polyoma_lg_T_C PF06431.6 EGO52903.1 - 1.1 7.8 3.2 1.7 7.2 2.2 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus SAPS PF04499.10 EGO52903.1 - 2.5 6.6 10.1 3.6 6.1 7.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF726 PF05277.7 EGO52904.1 - 7.4e-98 327.6 12.8 3.2e-73 246.6 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF726) DUF3439 PF11921.3 EGO52904.1 - 0.045 13.5 6.9 0.12 12.1 4.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF2149 PF09919.4 EGO52904.1 - 0.35 10.9 2.7 48 4.1 0.1 3.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2149) Dicty_REP PF05086.7 EGO52904.1 - 7.4 4.1 10.6 12 3.4 7.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Acylphosphatase PF00708.13 EGO52905.1 - 6.1e-27 93.5 0.2 6.7e-27 93.4 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase V-ATPase_H_N PF03224.9 EGO52906.1 - 1.6e-80 270.5 0.0 2.5e-80 269.9 0.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EGO52906.1 - 3.1e-39 133.5 0.0 1.9e-38 131.0 0.0 2.2 2 0 0 2 2 2 1 V-ATPase subunit H Sporozoite_P67 PF05642.6 EGO52907.1 - 1.2 6.8 15.2 1.9 6.2 10.4 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Glycophorin_A PF01102.13 EGO52907.1 - 3.5 7.4 7.5 0.33 10.7 0.5 2.5 2 0 0 2 2 2 0 Glycophorin A Ribosomal_L6 PF00347.18 EGO52908.1 - 6.7e-25 87.4 11.7 3.5e-12 46.6 3.5 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Vps26 PF03643.10 EGO52909.1 - 3.9e-131 435.8 0.8 4.6e-131 435.6 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EGO52909.1 - 6.7e-05 22.7 0.0 0.18 11.6 0.0 3.4 1 1 1 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Nup160 PF11715.3 EGO52910.1 - 6.7e-154 513.0 0.9 1.2e-151 505.5 0.6 2.3 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Rad51 PF08423.6 EGO52911.1 - 9.3e-28 96.8 0.0 1e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Rad51 zf-UDP PF14569.1 EGO52913.1 - 0.86 9.4 5.9 2.1 8.1 4.1 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_2 PF13639.1 EGO52913.1 - 2.2 8.1 10.5 5 7.0 7.3 1.6 1 0 0 1 1 1 0 Ring finger domain EF-hand_1 PF00036.27 EGO52915.1 - 1.5e-27 92.7 9.1 1.2e-06 27.3 0.1 5.4 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 EGO52915.1 - 3.6e-25 87.8 5.8 3.3e-10 39.9 0.2 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EGO52915.1 - 5.7e-22 75.5 8.5 0.0008 19.0 0.3 5.3 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.1 EGO52915.1 - 3.6e-19 68.1 14.1 9.6e-10 37.9 0.0 5.1 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 EGO52915.1 - 3e-17 61.0 12.8 5.3e-05 22.3 0.4 5.0 5 0 0 5 5 5 4 EF hand ChaC PF04752.7 EGO52916.1 - 2.1e-55 187.4 0.0 2.8e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein RRM_1 PF00076.17 EGO52917.1 - 1.1e-20 73.0 0.0 1.3e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO52917.1 - 2.5e-15 56.2 0.1 2.9e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO52917.1 - 1e-09 38.0 0.0 1.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HpcH_HpaI PF03328.9 EGO52919.1 - 2.6e-42 144.1 0.0 5.9e-42 143.0 0.0 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EGO52919.1 - 9e-15 54.3 0.2 8.5e-07 28.1 0.0 2.0 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF3656 PF12392.3 EGO52919.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Collagenase DUF846 PF05832.7 EGO52920.1 - 2.9e-53 179.3 7.8 3.5e-53 179.1 5.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) YwiC PF14256.1 EGO52920.1 - 0.052 13.6 8.8 0.13 12.2 1.2 2.1 2 0 0 2 2 2 0 YwiC-like protein DUF4191 PF13829.1 EGO52920.1 - 2.9 6.9 8.4 1.6 7.8 0.9 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4191) SKG6 PF08693.5 EGO52921.1 - 0.024 13.9 1.0 0.042 13.1 0.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rax2 PF12768.2 EGO52921.1 - 0.025 13.7 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Hep_59 PF07052.6 EGO52922.1 - 4.7e-20 71.8 0.5 4.7e-20 71.8 0.3 2.2 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 WD40 PF00400.27 EGO52924.1 - 1.6e-25 88.0 9.6 4e-07 29.6 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EGO52924.1 - 0.0035 15.5 0.4 0.0035 15.5 0.3 2.2 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGO52924.1 - 0.043 12.5 0.0 3.7 6.1 0.0 3.1 2 1 0 3 3 3 0 Nup133 N terminal like HA2 PF04408.18 EGO52925.1 - 3.4e-26 91.2 0.0 1.6e-25 89.1 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGO52925.1 - 5.5e-24 84.1 0.0 1.5e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold GCV_T PF01571.16 EGO52926.1 - 5.3e-36 123.9 0.0 6.8e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EGO52926.1 - 6.8e-24 83.7 0.4 1.2e-23 82.9 0.3 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Choline_kinase PF01633.15 EGO52927.1 - 2.1e-57 194.1 0.0 2.8e-56 190.4 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EGO52927.1 - 4.3e-08 33.1 1.8 6.1e-08 32.6 0.2 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGO52927.1 - 0.075 12.1 0.0 0.79 8.8 0.0 2.3 1 1 0 1 1 1 0 Ecdysteroid kinase NPR3 PF03666.8 EGO52928.1 - 5.1e-146 486.7 0.1 5.1e-146 486.7 0.0 1.5 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 EGO52928.1 - 0.2 10.3 0.1 0.44 9.1 0.1 1.5 1 0 0 1 1 1 0 Nitrogen permease regulator 2 HLH PF00010.21 EGO52929.1 - 2.2e-12 46.4 0.0 6.5e-12 44.9 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Got1 PF04178.7 EGO52930.1 - 4e-32 110.8 15.6 5.3e-32 110.4 10.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 EGO52930.1 - 0.0019 17.2 0.1 0.0042 16.0 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M50 Herpes_LMP1 PF05297.6 EGO52930.1 - 0.96 8.3 10.6 1.3 7.9 7.4 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Claudin_2 PF13903.1 EGO52930.1 - 2.2 7.9 12.2 0.4 10.3 1.2 2.2 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction La PF05383.12 EGO52934.1 - 9.6e-17 60.5 0.0 1.6e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 La domain LMBR1 PF04791.11 EGO52934.1 - 4.7 5.6 8.9 8 4.9 6.2 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein HLH PF00010.21 EGO52935.1 - 0.0034 17.0 0.2 0.005 16.5 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Taxilin PF09728.4 EGO52935.1 - 0.073 12.1 3.4 0.091 11.8 2.3 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Med4 PF10018.4 EGO52935.1 - 2.7 7.3 6.1 0.35 10.2 0.8 2.0 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 FG-GAP PF01839.18 EGO52936.1 - 0.064 12.9 1.3 0.17 11.6 0.9 1.7 1 0 0 1 1 1 0 FG-GAP repeat DUF4321 PF14209.1 EGO52937.1 - 0.12 12.0 1.3 0.15 11.7 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4321) TPR_14 PF13428.1 EGO52938.1 - 3.2e-27 92.5 16.1 2.7e-06 27.5 0.2 11.0 9 1 4 13 13 12 7 Tetratricopeptide repeat HAT PF02184.11 EGO52938.1 - 3e-26 90.8 59.3 6.2e-11 41.8 0.9 12.4 13 0 0 13 13 13 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 EGO52938.1 - 3.2e-21 75.4 0.0 2.9e-07 30.7 0.0 7.5 6 2 2 8 8 8 4 Tetratricopeptide repeat Suf PF05843.9 EGO52938.1 - 3.9e-15 56.3 16.0 0.00068 19.4 0.4 6.8 3 1 3 6 6 6 4 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EGO52938.1 - 2.1e-12 47.3 26.8 8.2e-05 23.1 0.2 8.2 9 2 4 13 13 10 5 Tetratricopeptide repeat TPR_15 PF13429.1 EGO52938.1 - 1.7e-07 30.5 13.0 0.012 14.7 1.0 6.0 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGO52938.1 - 3.5e-07 30.2 14.4 0.31 11.5 0.0 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO52938.1 - 5.9e-07 29.3 14.9 3.5 7.6 0.1 8.4 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGO52938.1 - 4.7e-06 26.1 1.3 0.015 14.8 0.1 5.5 6 1 1 7 7 7 1 TPR repeat TPR_17 PF13431.1 EGO52938.1 - 2.7e-05 24.0 0.4 2.8 8.3 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGO52938.1 - 0.00026 20.7 8.9 0.47 10.3 0.0 6.1 7 0 0 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 EGO52938.1 - 0.0053 16.5 17.6 0.04 13.8 0.0 8.3 10 0 0 10 10 10 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EGO52938.1 - 0.049 13.4 27.4 0.033 13.9 0.9 6.7 6 1 1 7 7 7 0 U3 small nucleolar RNA-associated protein 6 TPR_7 PF13176.1 EGO52938.1 - 0.091 12.6 11.8 14 5.8 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Prp31_C PF09785.4 EGO52939.1 - 2.6e-44 150.6 1.1 2.6e-44 150.6 0.8 2.0 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 EGO52939.1 - 1.6e-39 134.5 0.0 3e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGO52939.1 - 4.6e-16 58.3 0.0 1.9e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 NOSIC (NUC001) domain zf-C2H2_4 PF13894.1 EGO52942.1 - 1.3e-05 25.1 7.4 0.0012 19.0 0.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO52942.1 - 0.00018 21.6 10.7 0.0055 16.9 0.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO52942.1 - 0.0029 17.8 1.5 0.0029 17.8 1.0 2.9 3 0 0 3 3 3 1 Zinc-finger double domain Integrin_B_tail PF07965.7 EGO52942.1 - 0.028 14.8 0.6 0.086 13.2 0.1 1.9 1 1 1 2 2 2 0 Integrin beta tail domain Ribosomal_S15 PF00312.17 EGO52942.1 - 0.12 12.1 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S15 zf-TRAF PF02176.13 EGO52942.1 - 0.4 11.0 3.9 1.3 9.4 0.3 2.3 1 1 1 2 2 2 0 TRAF-type zinc finger zf-met PF12874.2 EGO52942.1 - 0.46 10.7 5.2 8.9 6.6 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Acetate_kinase PF00871.12 EGO52944.1 - 2.8e-83 279.6 0.0 4.9e-83 278.8 0.0 1.3 1 1 0 1 1 1 1 Acetokinase family HTH_29 PF13551.1 EGO52945.1 - 0.00052 20.1 0.0 0.00052 20.1 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.1 EGO52945.1 - 0.00053 19.4 0.3 0.14 11.7 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.1 EGO52945.1 - 0.024 14.2 0.2 3.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain DUF4175 PF13779.1 EGO52945.1 - 0.057 11.1 19.4 0.064 10.9 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.9 EGO52945.1 - 0.26 10.9 8.6 0.37 10.4 5.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 EGO52945.1 - 0.47 8.6 24.0 0.66 8.1 16.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PI31_Prot_C PF08577.6 EGO52945.1 - 9.4 6.9 11.0 88 3.8 7.6 2.3 1 1 0 1 1 1 0 PI31 proteasome regulator STT3 PF02516.9 EGO52947.1 - 6.8e-129 430.9 39.6 2.1e-124 416.1 25.9 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Ribosomal_L29 PF00831.18 EGO52948.1 - 2.3e-17 62.4 1.1 2.3e-17 62.4 0.7 1.9 2 0 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 EGO52948.1 - 0.011 15.9 1.1 0.013 15.7 0.8 1.2 1 0 0 1 1 1 0 Ribosomal protein S9/S16 YPEB PF14620.1 EGO52948.1 - 0.16 10.9 1.0 0.21 10.5 0.7 1.1 1 0 0 1 1 1 0 YpeB sporulation Ribosomal_L6e PF01159.14 EGO52949.1 - 3.8e-38 130.0 0.4 6e-38 129.4 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e V-SNARE_C PF12352.3 EGO52950.1 - 3.5e-13 49.3 0.3 3.5e-13 49.3 0.2 3.1 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus IncA PF04156.9 EGO52950.1 - 0.01 15.4 4.9 0.011 15.3 2.6 1.6 2 0 0 2 2 2 0 IncA protein PGC7_Stella PF15549.1 EGO52950.1 - 0.47 10.4 4.1 0.3 11.0 1.2 1.9 1 1 1 2 2 2 0 PGC7/Stella/Dppa3 domain ATP-synt_10 PF05176.9 EGO52951.1 - 6.5e-93 310.6 0.0 8.5e-93 310.2 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein 2-oxoacid_dh PF00198.18 EGO52952.1 - 9.2e-75 250.8 0.0 1.4e-74 250.3 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGO52952.1 - 2e-17 62.5 0.1 3.8e-17 61.6 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EGO52952.1 - 1.4e-14 53.4 0.1 2.8e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain GRP PF07172.6 EGO52954.1 - 8.7e-05 22.9 4.1 0.00013 22.3 2.9 1.2 1 0 0 1 1 1 1 Glycine rich protein family AAA_17 PF13207.1 EGO52956.1 - 5.9e-12 46.4 0.0 7.8e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EGO52956.1 - 6e-12 45.7 0.0 7.6e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 EGO52956.1 - 1.4e-10 41.2 0.0 1.8e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO52956.1 - 4.5e-10 39.9 0.0 1.3e-09 38.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGO52956.1 - 8.1e-06 26.0 0.0 1.7e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EGO52956.1 - 0.0001 22.4 0.0 0.00085 19.5 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EGO52956.1 - 0.00021 20.1 0.0 0.0003 19.6 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EGO52956.1 - 0.00061 19.8 0.0 0.0012 18.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EGO52956.1 - 0.0025 17.7 0.0 0.012 15.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGO52956.1 - 0.0032 17.6 0.0 0.0083 16.2 0.0 1.7 2 0 0 2 2 1 1 RNA helicase AAA_5 PF07728.9 EGO52956.1 - 0.0046 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EGO52956.1 - 0.0053 16.7 0.0 0.012 15.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain PRK PF00485.13 EGO52956.1 - 0.0058 16.2 0.0 0.057 12.9 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 EGO52956.1 - 0.0063 16.8 0.0 0.0097 16.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 EGO52956.1 - 0.0075 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain APS_kinase PF01583.15 EGO52956.1 - 0.0085 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase NACHT PF05729.7 EGO52956.1 - 0.016 14.9 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain CoaE PF01121.15 EGO52956.1 - 0.025 14.0 0.0 0.067 12.5 0.0 1.7 2 0 0 2 2 2 0 Dephospho-CoA kinase Cytidylate_kin2 PF13189.1 EGO52956.1 - 0.027 14.4 0.0 0.082 12.8 0.0 1.8 1 1 1 2 2 2 0 Cytidylate kinase-like family Sigma54_activ_2 PF14532.1 EGO52956.1 - 0.033 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 EGO52956.1 - 0.038 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EGO52956.1 - 0.045 12.8 0.0 0.083 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin tRNA_lig_kinase PF08303.6 EGO52956.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 tRNA ligase kinase domain Mg_chelatase PF01078.16 EGO52956.1 - 0.077 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EGO52956.1 - 0.083 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Thymidylate_kin PF02223.12 EGO52956.1 - 0.083 12.2 0.0 9.6 5.5 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase Viral_helicase1 PF01443.13 EGO52956.1 - 0.096 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EGO52956.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_M49 PF03571.10 EGO52957.1 - 2.6e-208 692.5 0.0 6.4e-181 602.1 0.0 2.0 1 1 1 2 2 2 2 Peptidase family M49 DUF3074 PF11274.3 EGO52958.1 - 4.1e-50 169.9 0.0 5.5e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) zf-H2C2_2 PF13465.1 EGO52959.1 - 2.8e-23 81.0 36.4 2e-09 37.2 0.1 6.2 6 0 0 6 6 6 5 Zinc-finger double domain zf-C2H2 PF00096.21 EGO52959.1 - 3e-17 61.8 45.5 5.6e-06 26.3 0.9 8.4 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO52959.1 - 2.1e-14 52.6 41.9 0.00093 19.3 0.3 8.3 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGO52959.1 - 9.1e-10 38.1 19.9 0.0014 18.4 0.2 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO52959.1 - 6.1e-05 23.0 18.8 0.12 12.5 0.4 5.7 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EGO52959.1 - 0.028 14.0 13.2 0.034 13.8 0.2 4.5 4 0 0 4 4 4 0 zinc-finger of a C2HC-type GAGA PF09237.6 EGO52959.1 - 0.4 10.3 0.0 0.4 10.3 0.0 3.2 2 1 2 4 4 4 0 GAGA factor zf-BED PF02892.10 EGO52959.1 - 3.9 7.3 21.3 5.9 6.7 1.4 4.4 1 1 3 4 4 4 0 BED zinc finger DEAD PF00270.24 EGO52962.1 - 2.7e-47 160.3 0.0 7.6e-46 155.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO52962.1 - 4e-24 84.2 0.0 7.9e-24 83.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGO52962.1 - 0.00014 20.7 0.0 0.00046 19.0 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 EGO52962.1 - 0.00015 21.6 0.0 0.00039 20.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HMG_box PF00505.14 EGO52963.1 - 3.1e-15 56.2 11.1 1.1e-09 38.4 0.2 3.1 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO52963.1 - 9e-14 51.6 6.9 3.8e-10 39.9 0.5 2.9 3 0 0 3 3 3 2 HMG-box domain HMG_box_5 PF14887.1 EGO52963.1 - 0.049 13.4 0.8 0.049 13.4 0.5 2.9 3 0 0 3 3 3 0 HMG (high mobility group) box 5 Sir1 PF11603.3 EGO52963.1 - 0.14 12.3 1.0 0.22 11.6 0.7 1.3 1 0 0 1 1 1 0 Regulatory protein Sir1 DUF1289 PF06945.8 EGO52963.1 - 0.68 9.4 3.5 19 4.8 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) 3Beta_HSD PF01073.14 EGO52965.1 - 9.7e-67 224.5 0.0 1.1e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGO52965.1 - 3.1e-31 108.6 0.2 4.5e-31 108.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGO52965.1 - 2e-17 62.9 1.9 6.5e-15 54.7 0.2 2.2 1 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EGO52965.1 - 2.8e-15 55.9 0.1 3.5e-15 55.6 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGO52965.1 - 1.8e-12 47.6 0.1 2.7e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGO52965.1 - 1e-08 34.4 0.4 4.6e-08 32.3 0.2 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EGO52965.1 - 4.4e-07 29.9 0.2 9.2e-07 28.9 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO52965.1 - 4e-06 26.6 1.1 1e-05 25.2 0.7 1.6 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EGO52965.1 - 2.9e-05 23.4 0.1 5e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EGO52965.1 - 0.0013 18.7 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_3 PF03447.11 EGO52965.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 EGO52965.1 - 0.092 12.6 0.2 0.24 11.3 0.1 1.8 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF2457 PF10446.4 EGO52966.1 - 0.071 11.8 21.2 0.16 10.7 14.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2890 PF11081.3 EGO52966.1 - 0.089 12.8 4.5 0.19 11.7 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 EGO52966.1 - 0.2 9.5 16.7 0.27 9.1 11.5 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 EGO52966.1 - 1.6 7.0 18.6 0.092 11.1 9.4 1.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 EGO52966.1 - 2.9 6.2 15.9 0.43 9.0 8.2 1.7 2 0 0 2 2 2 0 Daxx Family SDA1 PF05285.7 EGO52966.1 - 5.1 6.2 18.2 7.7 5.6 12.6 1.2 1 0 0 1 1 1 0 SDA1 DUF2417 PF10329.4 EGO52968.1 - 4.6e-67 225.8 4.9 1.3e-54 185.0 2.4 2.1 1 1 1 2 2 2 2 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EGO52968.1 - 0.0002 21.3 1.4 0.0002 21.3 0.9 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF4401 PF14351.1 EGO52968.1 - 0.0035 16.3 5.4 0.0055 15.7 3.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) K_trans PF02705.11 EGO52968.1 - 0.6 8.3 5.1 0.85 7.9 3.5 1.2 1 0 0 1 1 1 0 K+ potassium transporter DUF3357 PF11837.3 EGO52968.1 - 0.95 9.3 5.3 3.8 7.3 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) RhoGAP PF00620.22 EGO52969.1 - 4.1e-34 117.3 0.0 7.6e-34 116.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EGO52969.1 - 1e-30 105.5 41.3 3.3e-11 43.0 4.9 5.0 5 0 0 5 5 5 4 LIM domain UQ_con PF00179.21 EGO52970.1 - 2e-41 140.6 0.0 1.6e-29 102.0 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO52970.1 - 0.00035 20.3 0.0 1 9.1 0.0 2.5 2 1 0 2 2 2 2 Prokaryotic E2 family B UEV PF05743.8 EGO52970.1 - 0.0055 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 UEV domain AAA PF00004.24 EGO52971.1 - 2e-15 57.1 0.0 5.1e-15 55.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EGO52971.1 - 3.1e-12 46.4 0.0 4.7e-11 42.6 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EGO52971.1 - 1.1e-11 44.5 0.0 2.5e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 EGO52971.1 - 3.3e-11 42.5 0.0 2.5e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EGO52971.1 - 8.3e-07 29.2 0.0 9.7e-06 25.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGO52971.1 - 1.8e-06 27.2 0.0 4.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGO52971.1 - 9.8e-06 25.2 0.0 3.6e-05 23.4 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_11 PF13086.1 EGO52971.1 - 4.2e-05 23.2 0.0 8e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO52971.1 - 6e-05 23.1 0.1 0.0011 19.0 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 EGO52971.1 - 0.0003 20.6 0.0 0.00056 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGO52971.1 - 0.00072 18.7 0.0 0.012 14.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.8 EGO52971.1 - 0.00088 18.8 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF2075 PF09848.4 EGO52971.1 - 0.0018 17.3 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EGO52971.1 - 0.0029 18.4 0.0 0.006 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EGO52971.1 - 0.003 17.1 0.0 0.0071 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EGO52971.1 - 0.004 16.1 0.0 0.0062 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EGO52971.1 - 0.0046 16.4 0.1 0.035 13.5 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.1 EGO52971.1 - 0.0048 16.8 0.0 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGO52971.1 - 0.0056 16.1 0.1 0.032 13.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGO52971.1 - 0.0099 15.6 0.1 0.12 12.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EGO52971.1 - 0.014 15.0 0.3 0.11 11.9 0.0 2.5 2 2 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGO52971.1 - 0.016 15.5 0.0 0.043 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 EGO52971.1 - 0.031 12.9 0.0 0.52 8.9 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus SNF2_N PF00176.18 EGO52971.1 - 0.056 12.2 0.0 1.1 8.0 0.0 2.3 1 1 0 2 2 2 0 SNF2 family N-terminal domain DEAD PF00270.24 EGO52971.1 - 0.058 12.8 0.0 0.97 8.9 0.0 2.5 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_33 PF13671.1 EGO52971.1 - 0.061 13.1 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGO52971.1 - 0.063 12.7 0.1 1.1 8.6 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain ResIII PF04851.10 EGO52971.1 - 0.076 12.8 0.0 0.28 10.9 0.0 1.8 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 EGO52971.1 - 0.095 12.8 0.0 0.21 11.7 0.0 1.8 1 1 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EGO52971.1 - 0.13 11.9 0.0 0.33 10.5 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase DUF2360 PF10152.4 EGO52972.1 - 0.043 14.1 2.6 0.13 12.5 1.8 2.0 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF4611 PF15387.1 EGO52972.1 - 1.8 8.7 9.5 0.17 12.0 1.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) Sec63 PF02889.11 EGO52973.1 - 8.4e-197 652.6 0.9 1.7e-108 362.5 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EGO52973.1 - 3.3e-55 186.1 0.2 4.6e-32 110.8 0.0 3.9 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EGO52973.1 - 1.8e-16 60.5 0.0 2.7e-08 33.8 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGO52973.1 - 1.2e-11 44.3 0.0 1.5e-09 37.6 0.0 3.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGO52973.1 - 1.6e-08 34.7 0.1 0.0068 16.5 0.0 3.3 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EGO52973.1 - 8.4e-05 21.5 0.0 0.19 10.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 EGO52973.1 - 0.0014 18.1 0.2 4.2 6.7 0.0 3.9 3 2 2 5 5 5 2 AAA-like domain IstB_IS21 PF01695.12 EGO52973.1 - 0.0018 17.7 0.1 0.3 10.4 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein PhoH PF02562.11 EGO52973.1 - 0.0028 16.9 0.0 0.31 10.2 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein FtsK_SpoIIIE PF01580.13 EGO52973.1 - 0.0028 17.1 0.0 3.3 7.1 0.0 2.8 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_19 PF13245.1 EGO52973.1 - 0.027 14.2 0.0 3.7 7.3 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain Sigma54_activat PF00158.21 EGO52973.1 - 0.1 12.0 0.0 0.94 8.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain PWWP PF00855.12 EGO52974.1 - 5e-13 49.0 0.0 5e-13 49.0 0.0 3.3 4 1 0 4 4 4 1 PWWP domain ORC3_N PF07034.6 EGO52975.1 - 1.3e-34 119.6 0.0 2.9e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Barstar PF01337.13 EGO52975.1 - 0.096 12.5 0.6 2.2 8.1 0.0 3.0 3 0 0 3 3 3 0 Barstar (barnase inhibitor) Sec66 PF09802.4 EGO52977.1 - 4.5e-80 267.5 0.4 5.1e-80 267.3 0.3 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF4456 PF14644.1 EGO52977.1 - 0.099 11.8 0.8 0.16 11.2 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) PaREP1 PF05942.6 EGO52977.1 - 3.4 7.5 6.6 2 8.3 0.6 2.3 1 1 1 2 2 2 0 Archaeal PaREP1/PaREP8 family NPL4 PF05021.10 EGO52978.1 - 1.6e-129 431.5 0.0 2e-129 431.1 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EGO52978.1 - 5.9e-71 236.8 0.1 1.1e-70 236.0 0.1 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region DUF4451 PF14616.1 EGO52978.1 - 0.051 13.3 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) COesterase PF00135.23 EGO52979.1 - 4.8e-92 309.3 0.0 1.9e-91 307.3 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO52979.1 - 0.0032 17.0 0.0 0.0073 15.9 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO52979.1 - 0.004 16.9 0.1 0.0064 16.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO52979.1 - 0.093 11.9 0.1 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4187 PF13821.1 EGO52980.1 - 4.1e-19 67.9 2.5 1e-18 66.6 1.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EGO52980.1 - 8.5e-11 41.4 0.8 1.6e-10 40.6 0.6 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EGO52980.1 - 0.011 15.6 2.9 0.012 15.4 0.4 2.4 2 0 0 2 2 2 0 DExH-box splicing factor binding site Mito_fiss_reg PF05308.6 EGO52980.1 - 4.7 6.5 10.9 6.1 6.1 6.9 1.6 1 1 0 1 1 1 0 Mitochondrial fission regulator CPSase_L_D2 PF02786.12 EGO52981.1 - 3.4e-112 372.8 0.1 4.6e-85 284.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EGO52981.1 - 5e-41 139.3 0.1 1.2e-40 138.1 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EGO52981.1 - 1.1e-38 132.8 0.2 4.6e-21 75.3 0.1 2.8 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 EGO52981.1 - 4.1e-35 120.2 0.0 3e-16 59.4 0.0 3.0 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EGO52981.1 - 1.3e-26 93.1 0.0 1e-09 37.6 0.0 3.6 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EGO52981.1 - 2.2e-22 79.2 0.2 5.6e-10 38.8 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGO52981.1 - 7.7e-18 64.6 0.6 1.3e-08 34.5 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EGO52981.1 - 2.1e-09 37.1 0.0 9.1e-06 25.2 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.14 EGO52981.1 - 6.6e-07 29.0 0.4 0.043 13.3 0.1 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 EGO52981.1 - 3.1e-06 27.1 0.2 0.044 13.6 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.1 EGO52981.1 - 0.0003 20.0 0.1 0.1 11.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Epimerase PF01370.16 EGO52981.1 - 0.088 12.2 0.0 2 7.7 0.0 2.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1746 PF08508.5 EGO52982.1 - 6.2e-42 142.2 0.2 8.8e-42 141.7 0.1 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RCR PF12273.3 EGO52982.1 - 0.14 12.7 3.7 33 5.0 3.8 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red CDC45 PF02724.9 EGO52982.1 - 0.15 10.1 2.5 0.21 9.6 1.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RTC PF01137.16 EGO52983.1 - 1.7e-32 112.0 0.1 2.5e-32 111.5 0.1 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EGO52983.1 - 2e-32 111.2 0.1 3.6e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PPR_2 PF13041.1 EGO52984.1 - 2.1e-10 40.3 0.3 0.00076 19.4 0.0 5.1 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.15 EGO52984.1 - 1.8e-05 24.4 1.7 1.3 9.1 0.0 5.6 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.1 EGO52984.1 - 0.0089 16.2 8.4 25 5.4 0.0 6.9 8 0 0 8 8 8 1 Pentatricopeptide repeat domain BcrAD_BadFG PF01869.15 EGO52984.1 - 0.17 11.1 0.9 0.44 9.7 0.1 2.0 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family TnpV PF14198.1 EGO52984.1 - 2.4 8.0 6.1 1.8 8.4 0.0 3.4 5 0 0 5 5 5 0 Transposon-encoded protein TnpV zf-C2H2 PF00096.21 EGO52988.1 - 5e-12 45.4 13.9 4.1e-06 26.8 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO52988.1 - 1.3e-08 34.5 10.8 0.0013 18.8 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGO52988.1 - 3.8e-08 33.2 13.1 4.4e-06 26.7 3.4 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EGO52988.1 - 4.7e-05 23.1 11.2 0.00067 19.4 0.3 2.8 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO52988.1 - 7.6e-05 22.7 6.3 0.0076 16.3 1.5 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGO52988.1 - 0.00026 21.0 4.9 0.01 15.9 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type PRP21_like_P PF12230.3 EGO52988.1 - 0.82 9.1 8.5 1.3 8.5 5.9 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Elf1 PF05129.8 EGO52988.1 - 2 8.1 5.8 12 5.7 0.4 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Menin PF05053.8 EGO52988.1 - 3 5.8 8.5 4.5 5.3 5.9 1.1 1 0 0 1 1 1 0 Menin zf-BED PF02892.10 EGO52988.1 - 7.7 6.3 10.0 4.6 7.0 0.2 2.4 1 1 1 2 2 2 0 BED zinc finger ATP_bind_4 PF01902.12 EGO52989.1 - 2.1e-21 76.2 0.0 1.2e-14 54.1 0.0 4.0 3 1 0 3 3 3 2 ATP-binding region Ribonuc_L-PSP PF01042.16 EGO52989.1 - 1.4e-13 50.7 0.2 9.8e-09 35.0 0.0 3.8 4 0 0 4 4 4 2 Endoribonuclease L-PSP CENP-B_dimeris PF09026.5 EGO52989.1 - 1.5 9.1 22.9 0.17 12.1 0.6 4.5 4 0 0 4 4 4 0 Centromere protein B dimerisation domain BNR PF02012.15 EGO52990.1 - 3.8e-12 44.0 35.2 0.13 12.1 0.1 10.2 10 0 0 10 10 10 7 BNR/Asp-box repeat DUF2561 PF10812.3 EGO52990.1 - 0.016 14.8 0.1 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) SUN PF03856.8 EGO52991.1 - 1.3e-87 293.2 11.6 1.8e-87 292.7 8.0 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF515 PF04415.7 EGO52991.1 - 0.21 9.7 5.8 0.27 9.4 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Antimicrobial10 PF08105.6 EGO52991.1 - 0.41 10.3 3.4 12 5.6 0.5 2.6 2 0 0 2 2 2 0 Metchnikowin family KAR9 PF08580.5 EGO52991.1 - 4.5 5.4 7.4 6 5.0 5.1 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 zf-H2C2_2 PF13465.1 EGO52992.1 - 1.8e-10 40.5 10.2 8.1e-08 32.1 1.8 4.9 5 0 0 5 5 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EGO52992.1 - 2.1e-08 34.0 32.7 0.004 17.4 5.4 4.6 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO52992.1 - 0.0018 18.4 11.2 0.006 16.8 4.3 5.4 7 0 0 7 7 3 3 C2H2-type zinc finger Baculo_PEP_C PF04513.7 EGO52992.1 - 0.0037 17.0 8.6 0.0048 16.7 5.3 1.6 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EGO52992.1 - 0.0061 15.7 4.6 0.0099 15.0 3.2 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 EGO52992.1 - 0.026 12.4 11.7 0.039 11.8 8.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin PF00261.15 EGO52992.1 - 0.027 13.5 8.1 0.048 12.7 5.6 1.4 1 0 0 1 1 1 0 Tropomyosin Erp_C PF06780.6 EGO52992.1 - 0.045 13.5 0.1 0.08 12.7 0.1 1.3 1 0 0 1 1 1 0 Erp protein C-terminus Cir_Bir_Yir PF06022.6 EGO52992.1 - 0.11 11.7 6.1 0.17 11.0 4.3 1.3 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Cyc-maltodext_C PF10438.4 EGO52992.1 - 0.11 12.5 0.4 0.19 11.8 0.2 1.4 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain zf-CHCC PF10276.4 EGO52992.1 - 0.12 12.2 6.5 0.68 9.8 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger domain zf-C2HC_2 PF13913.1 EGO52992.1 - 0.22 11.2 5.8 0.1 12.2 0.4 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 EGO52992.1 - 0.5 10.3 0.1 0.5 10.3 0.0 4.5 4 0 0 4 4 3 0 C2H2-type zinc finger BLOC1_2 PF10046.4 EGO52992.1 - 0.74 9.9 11.7 0.47 10.6 4.2 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DZR PF12773.2 EGO52992.1 - 1 9.2 5.5 9.1 6.1 3.9 2.3 1 1 0 1 1 1 0 Double zinc ribbon YfhO PF09586.5 EGO52992.1 - 1 7.2 4.4 1.4 6.8 3.0 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO FlaC_arch PF05377.6 EGO52992.1 - 1.1 9.1 2.8 17 5.3 0.2 2.5 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.3 EGO52992.1 - 1.2 8.9 17.3 0.048 13.4 2.5 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding zf-RING_3 PF14369.1 EGO52992.1 - 2.7 8.0 6.3 32 4.6 0.1 3.1 2 1 1 3 3 3 0 zinc-finger Zn-ribbon_8 PF09723.5 EGO52992.1 - 7 6.6 9.3 36 4.4 2.3 3.2 1 1 2 3 3 3 0 Zinc ribbon domain DAGAT PF03982.8 EGO52993.1 - 1.2e-93 313.0 0.0 1.7e-93 312.6 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase LAM_C PF12544.3 EGO52996.1 - 0.00024 21.1 0.0 0.00055 19.9 0.0 1.5 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.16 EGO52996.1 - 0.0082 16.3 0.0 0.036 14.2 0.0 2.1 1 1 0 1 1 1 1 Radical SAM superfamily MFS_1 PF07690.11 EGO52997.1 - 1.2e-09 37.4 5.7 1.4e-09 37.1 4.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO52997.1 - 6.7e-05 21.6 1.8 7.6e-05 21.4 1.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter FtsX PF02687.16 EGO52997.1 - 0.11 12.3 2.0 0.55 10.0 1.3 2.1 1 1 1 2 2 2 0 FtsX-like permease family MFS_2 PF13347.1 EGO52997.1 - 0.16 10.2 3.3 0.09 11.1 1.1 1.4 1 1 0 1 1 1 0 MFS/sugar transport protein Claudin_2 PF13903.1 EGO52997.1 - 1 9.0 7.3 0.19 11.4 0.8 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction SHS2_Rpb7-N PF03876.12 EGO53000.1 - 2.8e-15 56.1 0.0 4.8e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EGO53000.1 - 9e-10 38.5 0.0 1.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EGO53000.1 - 0.0025 17.9 0.0 0.007 16.5 0.0 1.7 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 DUF962 PF06127.6 EGO53001.1 - 3.7e-25 87.6 0.0 6.1e-25 86.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Apq12 PF12716.2 EGO53002.1 - 2.6e-14 52.6 11.6 4.9e-14 51.7 8.1 1.5 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis HA PF03457.9 EGO53002.1 - 0.1 12.7 0.3 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Helicase associated domain ATP_bind_1 PF03029.12 EGO53003.1 - 1.6e-71 240.6 0.2 3.7e-71 239.4 0.1 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EGO53003.1 - 3.7e-05 24.5 0.0 9.6e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGO53003.1 - 0.00052 19.9 0.0 0.0015 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO53003.1 - 0.0021 17.9 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGO53003.1 - 0.0025 17.9 0.0 0.0061 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_10 PF12846.2 EGO53003.1 - 0.003 17.0 0.0 0.0062 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA-like domain MobB PF03205.9 EGO53003.1 - 0.0033 17.1 0.0 0.0068 16.1 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EGO53003.1 - 0.0034 17.5 0.0 0.0067 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EGO53003.1 - 0.0034 17.3 0.3 0.015 15.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EGO53003.1 - 0.0036 16.9 0.0 0.0073 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TRADD_N PF09034.5 EGO53003.1 - 0.0049 16.8 0.1 0.0086 16.0 0.1 1.4 1 0 0 1 1 1 1 TRADD, N-terminal domain AAA_29 PF13555.1 EGO53003.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thymidylate_kin PF02223.12 EGO53003.1 - 0.019 14.3 0.0 5.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase PPV_E1_C PF00519.12 EGO53003.1 - 0.027 13.1 0.0 0.051 12.1 0.0 1.4 1 0 0 1 1 1 0 Papillomavirus helicase ABC_tran PF00005.22 EGO53003.1 - 0.029 14.6 0.0 0.095 12.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter SRP54 PF00448.17 EGO53003.1 - 0.03 13.7 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain GTP_EFTU PF00009.22 EGO53003.1 - 0.035 13.5 0.0 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Septin PF00735.13 EGO53003.1 - 0.048 12.6 0.0 0.077 11.9 0.0 1.3 1 0 0 1 1 1 0 Septin NACHT PF05729.7 EGO53003.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EGO53003.1 - 0.059 13.3 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 EGO53003.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EGO53003.1 - 0.076 12.4 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EGO53003.1 - 0.099 12.9 0.0 0.28 11.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 EGO53003.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGO53003.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain CbiA PF01656.18 EGO53003.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.12 EGO53003.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein cobW PF02492.14 EGO53003.1 - 0.13 11.7 0.1 5 6.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EGO53003.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 EGO53003.1 - 0.14 12.6 0.0 2.1 8.8 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein S-AdoMet_synt_C PF02773.11 EGO53004.1 - 6.6e-77 255.8 0.3 1.1e-76 255.1 0.2 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EGO53004.1 - 2.9e-46 156.3 0.0 4.9e-46 155.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EGO53004.1 - 1.3e-42 144.0 0.4 2.8e-42 143.0 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain MFS_1 PF07690.11 EGO53006.1 - 2.1e-19 69.4 14.3 2.3e-13 49.5 5.3 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO53006.1 - 2.9e-05 22.8 15.9 0.00049 18.7 3.1 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Glyco_hydro_88 PF07470.8 EGO53007.1 - 1.9e-79 267.1 0.8 2.2e-79 266.9 0.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.9 EGO53007.1 - 1.2 8.3 7.6 0.13 11.6 0.9 2.2 1 1 1 2 2 2 0 Glycosyl hydrolase family 76 MFS_1 PF07690.11 EGO53008.1 - 3.7e-35 121.2 20.3 4.7e-35 120.9 14.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Microcin PF03526.8 EGO53008.1 - 0.091 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein DUF1049 PF06305.6 EGO53008.1 - 0.15 11.5 5.0 5.3 6.6 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Polyketide_cyc2 PF10604.4 EGO53009.1 - 0.0012 18.9 0.1 0.0035 17.5 0.0 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_32 PF13679.1 EGO53010.1 - 0.00017 21.2 0.0 0.0005 19.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO53010.1 - 0.0085 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO53010.1 - 0.0088 16.3 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGO53010.1 - 0.017 15.1 0.0 0.078 12.9 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EGO53010.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 EGO53010.1 - 0.13 11.3 0.0 0.32 10.0 0.0 1.6 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PCI PF01399.22 EGO53011.1 - 2.3e-21 76.0 0.4 7.3e-21 74.4 0.0 2.1 2 0 0 2 2 2 1 PCI domain Asp_Glu_race_2 PF14669.1 EGO53011.1 - 9e-05 21.8 2.3 0.18 11.1 0.2 2.3 2 0 0 2 2 2 2 Putative aspartate racemase PCI_Csn8 PF10075.4 EGO53011.1 - 0.013 15.3 0.1 0.038 13.7 0.0 1.8 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Methyltransf_23 PF13489.1 EGO53012.1 - 7e-19 68.1 0.0 1.6e-18 66.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO53012.1 - 5.7e-08 33.1 0.0 3.6e-07 30.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO53012.1 - 1.1e-07 32.4 0.0 3.4e-06 27.6 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO53012.1 - 1.2e-07 32.1 0.0 6.5e-07 29.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO53012.1 - 2.1e-05 24.1 0.0 0.00014 21.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO53012.1 - 0.0046 17.3 0.0 0.031 14.6 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO53012.1 - 0.022 13.8 0.0 0.047 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EGO53012.1 - 0.058 12.4 0.0 3.5 6.6 0.0 2.7 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 EGO53015.1 - 3.9e-33 114.6 0.0 5.7e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGO53015.1 - 0.0003 21.3 0.0 0.00072 20.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO53015.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain DUF3357 PF11837.3 EGO53019.1 - 0.025 14.4 1.0 0.06 13.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) EMP24_GP25L PF01105.19 EGO53019.1 - 0.042 13.5 0.3 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SlyX PF04102.7 EGO53019.1 - 0.77 10.1 5.0 0.36 11.2 0.3 2.6 2 1 0 2 2 2 0 SlyX Cgr1 PF03879.9 EGO53020.1 - 1.8e-39 134.2 27.7 2.3e-39 133.9 19.2 1.1 1 0 0 1 1 1 1 Cgr1 family PRP1_N PF06424.7 EGO53020.1 - 0.065 13.5 8.0 0.069 13.4 5.5 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal CAF-1_p150 PF11600.3 EGO53020.1 - 0.13 11.6 25.8 0.17 11.2 17.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 EGO53020.1 - 1.2 8.3 19.3 1.4 8.1 13.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.7 EGO53020.1 - 3.5 7.4 14.3 3.9 7.2 9.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.1 EGO53020.1 - 4.3 6.1 9.1 4.8 6.0 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAGA_bind PF06217.7 EGO53020.1 - 7.6 6.4 13.4 9.7 6.0 9.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family SprA-related PF12118.3 EGO53020.1 - 8.9 5.5 12.9 11 5.2 8.9 1.1 1 0 0 1 1 1 0 SprA-related family Arginosuc_synth PF00764.14 EGO53021.1 - 2.6e-145 484.3 0.0 3e-145 484.1 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EGO53021.1 - 0.00056 19.2 0.0 0.00087 18.6 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 EGO53021.1 - 0.0064 16.0 0.0 0.0089 15.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 EGO53021.1 - 0.035 12.6 0.0 0.059 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase UQ_con PF00179.21 EGO53023.1 - 7e-30 103.2 0.0 8.3e-30 103.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO53023.1 - 0.0008 19.1 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGO53023.1 - 0.013 15.3 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain Anp1 PF03452.9 EGO53024.1 - 4.9e-111 370.2 0.0 6.2e-111 369.8 0.0 1.0 1 0 0 1 1 1 1 Anp1 Proteasom_Rpn13 PF04683.8 EGO53025.1 - 8.5e-29 99.4 0.0 1.2e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RRM_1 PF00076.17 EGO53026.1 - 3.5e-12 45.7 0.1 0.00014 21.3 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO53026.1 - 1.5e-11 44.1 0.1 4.1e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO53026.1 - 7e-08 32.2 0.0 4.4e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfate_transp PF00916.15 EGO53027.1 - 3.4e-36 124.6 1.6 3.4e-36 124.6 1.1 2.0 1 1 1 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 EGO53027.1 - 3.9e-18 65.0 0.0 7.6e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EGO53027.1 - 1.2e-08 34.3 0.0 2.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain EAL PF00563.15 EGO53027.1 - 0.026 13.9 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 EAL domain Sld5 PF05916.6 EGO53028.1 - 2.1e-15 56.9 0.0 3.3e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein AAA_2 PF07724.9 EGO53029.1 - 1.6e-43 148.5 0.0 1.5e-42 145.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EGO53029.1 - 6.1e-26 90.1 0.2 2.2e-25 88.3 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EGO53029.1 - 9.6e-19 67.8 0.0 1.9e-10 41.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGO53029.1 - 1.3e-10 41.1 0.1 2.1e-08 33.9 0.0 3.0 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGO53029.1 - 3e-09 37.1 9.1 0.048 13.6 0.0 5.4 3 2 1 5 5 5 3 AAA ATPase domain AAA_22 PF13401.1 EGO53029.1 - 4.6e-08 33.2 1.1 0.0076 16.3 0.0 3.8 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EGO53029.1 - 5.8e-07 29.1 0.6 0.00037 20.0 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 EGO53029.1 - 2.7e-06 27.3 0.0 0.051 13.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EGO53029.1 - 3.4e-05 23.6 5.7 0.35 10.5 0.0 4.6 2 2 1 4 4 4 2 Archaeal ATPase IstB_IS21 PF01695.12 EGO53029.1 - 0.00019 20.9 0.1 0.45 9.9 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 EGO53029.1 - 0.0005 20.8 5.7 0.12 13.2 0.2 3.9 4 1 0 4 4 3 1 AAA domain AAA_18 PF13238.1 EGO53029.1 - 0.00052 20.3 5.3 0.28 11.4 0.0 3.6 4 0 0 4 4 3 2 AAA domain NACHT PF05729.7 EGO53029.1 - 0.0024 17.5 1.3 0.36 10.4 0.1 3.0 2 2 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 EGO53029.1 - 0.0035 17.3 0.8 2 8.3 0.0 3.8 3 1 0 3 3 3 1 AAA domain DUF258 PF03193.11 EGO53029.1 - 0.005 16.0 0.1 2.3 7.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 IncA PF04156.9 EGO53029.1 - 0.0055 16.3 7.4 0.015 14.8 5.2 1.7 1 0 0 1 1 1 1 IncA protein ABC_tran PF00005.22 EGO53029.1 - 0.012 15.8 0.6 2.7 8.2 0.0 3.5 3 1 0 3 3 3 0 ABC transporter MobB PF03205.9 EGO53029.1 - 0.014 15.0 0.1 2 8.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EGO53029.1 - 0.029 14.5 0.1 2.3 8.4 0.0 2.9 2 1 0 2 2 2 0 RNA helicase NUFIP1 PF10453.4 EGO53029.1 - 0.039 13.4 0.6 0.15 11.6 0.4 2.0 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) AAA_25 PF13481.1 EGO53029.1 - 0.046 13.1 0.3 6.5 6.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.17 EGO53029.1 - 0.052 12.9 0.1 3.3 7.0 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EGO53029.1 - 0.055 12.8 0.2 1.3 8.3 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain Mg_chelatase PF01078.16 EGO53029.1 - 0.087 11.9 0.9 5.7 6.0 0.1 3.2 2 2 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.12 EGO53029.1 - 0.13 11.8 0.1 3.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein APG6 PF04111.7 EGO53029.1 - 0.44 9.5 4.9 0.73 8.8 3.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_23 PF13476.1 EGO53029.1 - 0.97 9.7 9.0 3.7 7.8 3.0 3.3 4 0 0 4 4 3 0 AAA domain V_ATPase_I PF01496.14 EGO53029.1 - 2.1 6.0 2.9 3.1 5.5 2.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EGO53029.1 - 7.8 5.3 7.4 14 4.4 5.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AICARFT_IMPCHas PF01808.13 EGO53030.1 - 1.8e-108 362.4 0.0 2.2e-108 362.0 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EGO53030.1 - 5.5e-24 83.9 0.0 1.1e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain SH3_2 PF07653.12 EGO53031.1 - 0.0034 16.8 0.2 0.0065 15.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Kinesin PF00225.18 EGO53033.1 - 1.9e-97 325.9 0.0 3.5e-97 325.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF342 PF03961.8 EGO53033.1 - 0.14 10.5 6.7 0.037 12.4 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF342) p450 PF00067.17 EGO53035.1 - 9.4e-71 238.7 0.0 1.1e-70 238.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HIG_1_N PF04588.8 EGO53036.1 - 1.7e-07 30.8 3.0 1.7e-07 30.8 2.1 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF1703 PF08011.6 EGO53036.1 - 0.036 13.7 0.1 0.11 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1703) Bud13 PF09736.4 EGO53036.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex zf-H2C2_2 PF13465.1 EGO53037.1 - 4e-05 23.7 6.2 0.0032 17.6 0.4 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EGO53037.1 - 0.0012 18.9 8.3 0.028 14.5 0.1 4.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EGO53037.1 - 0.02 15.2 16.0 0.067 13.5 0.3 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGO53037.1 - 0.031 14.1 0.8 0.031 14.1 0.5 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO53037.1 - 1.5 9.2 21.6 0.16 12.3 1.1 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-met PF12874.2 EGO53037.1 - 8 6.8 8.5 8.1 6.7 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Kelch_3 PF13415.1 EGO53039.1 - 1.8e-43 145.7 20.2 6.4e-10 38.9 0.1 7.1 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EGO53039.1 - 1.4e-41 139.9 17.5 2e-09 37.0 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 EGO53039.1 - 5.1e-40 134.7 17.9 4.8e-08 32.4 0.9 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 EGO53039.1 - 6.9e-38 128.0 25.4 5.9e-07 29.3 0.1 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 EGO53039.1 - 1e-35 120.4 16.6 2.1e-07 30.7 0.2 6.3 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EGO53039.1 - 3e-33 112.3 14.6 6.2e-09 35.2 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Dus PF01207.12 EGO53040.1 - 6.5e-41 140.1 0.0 3.9e-32 111.3 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EGO53040.1 - 0.55 9.9 4.2 7.1 6.4 0.5 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Peroxin-13_N PF04088.8 EGO53041.1 - 2e-25 89.5 0.0 2.8e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EGO53041.1 - 6.6e-09 35.1 0.0 1.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO53041.1 - 2.7e-06 26.6 0.1 1e-05 24.8 0.1 1.9 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGO53041.1 - 2.1e-05 24.0 0.0 4.3e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Variant SH3 domain Rab5ip PF07019.7 EGO53041.1 - 0.088 12.9 0.0 0.3 11.2 0.0 1.9 1 1 1 2 2 2 0 Rab5-interacting protein (Rab5ip) Kelch_4 PF13418.1 EGO53042.1 - 1.4e-25 88.7 7.2 1.3e-08 34.4 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EGO53042.1 - 4.4e-25 87.1 0.7 2.3e-07 30.6 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 EGO53042.1 - 3.6e-23 80.6 1.8 6.8e-05 22.8 0.0 5.1 3 1 2 5 5 5 4 Kelch motif Kelch_1 PF01344.20 EGO53042.1 - 1.6e-21 75.5 0.3 5e-05 22.7 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.1 EGO53042.1 - 6.2e-20 70.8 5.8 3.1e-07 30.3 0.0 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EGO53042.1 - 5.8e-17 60.7 2.4 0.0016 18.1 0.0 4.7 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 EGO53042.1 - 3.2e-09 36.7 0.0 5.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.27 EGO53043.1 - 1.5e-25 88.0 17.1 1.7e-06 27.6 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EGO53043.1 - 4.7e-06 26.4 0.5 0.00025 20.8 0.1 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A TFIIA PF03153.8 EGO53044.1 - 6.7e-84 282.9 35.8 2.8e-82 277.5 24.8 2.0 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Prothymosin PF03247.9 EGO53044.1 - 0.0065 16.5 7.9 0.015 15.4 5.5 1.5 1 0 0 1 1 1 1 Prothymosin/parathymosin family Nop14 PF04147.7 EGO53044.1 - 0.82 7.5 6.2 1.4 6.7 4.3 1.3 1 0 0 1 1 1 0 Nop14-like family Pro_isomerase PF00160.16 EGO53045.1 - 1.5e-49 168.1 0.3 1.7e-49 167.9 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 EGO53045.1 - 0.044 13.5 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain TEA PF01285.13 EGO53047.1 - 7.8e-09 35.1 0.1 7.8e-09 35.1 0.1 3.9 4 0 0 4 4 4 1 TEA/ATTS domain family TFIIA PF03153.8 EGO53047.1 - 7 6.4 33.2 1.3 8.8 15.3 2.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.17 EGO53048.1 - 1.4e-66 220.0 5.4 2.2e-16 59.2 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO53048.1 - 7.9e-61 201.9 4.0 8.7e-15 54.4 0.0 5.8 6 0 0 6 6 6 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO53048.1 - 1.4e-32 111.3 0.1 1.5e-08 34.3 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGO53048.1 - 5.5e-08 32.4 0.0 0.0048 16.6 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EGO53048.1 - 3.2e-07 29.9 0.9 0.1 12.3 0.1 4.8 4 1 0 4 4 4 2 Limkain b1 Nup35_RRM PF05172.8 EGO53048.1 - 0.00065 19.4 0.0 0.0093 15.7 0.0 2.9 3 1 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Smg4_UPF3 PF03467.10 EGO53048.1 - 0.0016 18.4 0.4 2.3 8.1 0.0 3.2 3 0 0 3 3 3 2 Smg-4/UPF3 family RRM_3 PF08777.6 EGO53048.1 - 0.055 13.3 2.2 3 7.7 0.0 4.2 4 1 1 5 5 5 0 RNA binding motif Dynein_light PF01221.13 EGO53049.1 - 8.4e-42 141.0 1.9 9.7e-42 140.8 1.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ca_chan_IQ PF08763.6 EGO53050.1 - 0.025 13.7 0.1 0.055 12.7 0.1 1.6 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain Methyltransf_16 PF10294.4 EGO53051.1 - 3.8e-22 78.5 0.0 8.2e-22 77.4 0.0 1.4 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGO53051.1 - 0.0011 19.4 0.0 0.0052 17.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EGO53051.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGO53051.1 - 0.02 14.8 0.0 0.053 13.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EGO53051.1 - 0.051 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain RNA_pol_N PF01194.12 EGO53056.1 - 1.8e-29 101.5 0.7 2.3e-29 101.1 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EGO53056.1 - 0.007 16.4 0.2 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) WD40 PF00400.27 EGO53057.1 - 9.3e-11 41.1 3.3 0.0003 20.5 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat DIOX_N PF14226.1 EGO53059.1 - 4e-30 104.7 0.0 3.3e-28 98.5 0.0 2.2 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGO53059.1 - 5.9e-14 52.1 0.0 1.1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HHH PF00633.18 EGO53060.1 - 0.018 14.7 0.3 0.055 13.1 0.2 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif ANTAR PF03861.9 EGO53060.1 - 0.13 11.8 0.2 0.61 9.6 0.0 2.1 2 0 0 2 2 2 0 ANTAR domain DUF1479 PF07350.7 EGO53061.1 - 1.2e-130 435.8 1.3 1.6e-129 432.0 0.1 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.8 EGO53061.1 - 0.012 15.6 0.0 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Joubert PF15392.1 EGO53061.1 - 0.04 13.1 0.1 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Joubert syndrome-associated Bap31 PF05529.7 EGO53062.1 - 2.3e-65 219.6 4.3 2.6e-65 219.4 3.0 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Filament PF00038.16 EGO53062.1 - 0.0057 16.1 1.4 0.0081 15.6 1.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein Lge1 PF11488.3 EGO53062.1 - 0.015 15.4 0.8 0.029 14.5 0.5 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 IncA PF04156.9 EGO53062.1 - 0.033 13.7 1.5 0.061 12.9 1.0 1.5 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EGO53062.1 - 0.058 12.8 5.6 0.18 11.2 0.3 3.1 3 1 1 4 4 4 0 Septum formation initiator Phage_GP20 PF06810.6 EGO53062.1 - 0.11 11.8 6.5 0.16 11.4 4.5 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Amidohydro_1 PF01979.15 EGO53064.1 - 7.1e-16 58.7 0.2 4.5e-11 43.0 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EGO53064.1 - 1.2e-07 32.0 1.9 1.2e-06 28.8 1.3 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EGO53064.1 - 0.00014 21.6 0.4 0.0065 16.2 0.0 2.6 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EGO53064.1 - 0.0017 17.6 2.6 0.0044 16.2 0.9 2.2 2 1 0 2 2 2 1 Amidohydrolase family Asp-B-Hydro_N PF05279.6 EGO53065.1 - 2.8 7.7 8.1 3.4 7.4 5.6 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf-BED PF02892.10 EGO53066.1 - 2.8e-07 30.1 0.0 3.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 BED zinc finger zf-H2C2_5 PF13909.1 EGO53066.1 - 0.003 17.7 0.4 0.0047 17.0 0.3 1.4 1 0 0 1 1 1 1 C2H2-type zinc-finger domain RPA_interact_C PF14768.1 EGO53066.1 - 0.074 13.4 0.1 6.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Replication protein A interacting C-terminal EF-hand_2 PF09068.6 EGO53066.1 - 0.12 12.3 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 EF hand zf-HC2 PF13490.1 EGO53066.1 - 0.14 12.1 0.1 0.14 12.1 0.1 1.8 2 0 0 2 2 2 0 Putative zinc-finger DUF1687 PF07955.6 EGO53067.1 - 5.4e-31 107.3 0.0 7.1e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) ArsC PF03960.10 EGO53067.1 - 0.0057 16.7 0.0 0.18 11.8 0.0 2.1 1 1 0 1 1 1 1 ArsC family RRM_1 PF00076.17 EGO53068.1 - 6.5e-05 22.4 0.0 0.00056 19.5 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO53068.1 - 0.00061 19.7 0.0 0.0037 17.2 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO53068.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3716 PF12511.3 EGO53069.1 - 8.7e-13 47.6 3.7 1.4e-12 47.0 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Sel1 PF08238.7 EGO53070.1 - 3.6e-44 148.2 21.7 6.7e-07 29.7 0.7 7.7 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.1 EGO53070.1 - 0.39 11.2 3.4 5.3 7.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MBOAT PF03062.14 EGO53071.1 - 4.9e-40 137.6 20.6 4.9e-40 137.6 14.3 1.9 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Nop14 PF04147.7 EGO53072.1 - 0.00036 18.6 16.1 0.00067 17.7 11.1 1.3 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 EGO53072.1 - 0.0058 15.9 11.7 0.011 15.0 8.1 1.4 1 0 0 1 1 1 1 SDA1 DUF1510 PF07423.6 EGO53072.1 - 0.87 8.9 19.7 2.2 7.5 13.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Prefoldin_3 PF13758.1 EGO53073.1 - 1.2e-30 105.2 0.2 1.2e-30 105.2 0.2 2.8 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 EGO53073.1 - 1.8e-25 89.7 2.1 1.4e-22 80.4 0.0 5.4 5 1 1 6 6 6 2 Domain of unknown function (DUF3835) BTV_NS2 PF04514.7 EGO53073.1 - 1.6 7.5 14.2 0.087 11.6 6.1 1.6 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 CS PF04969.11 EGO53074.1 - 1.7e-18 66.9 0.0 5.7e-18 65.2 0.0 1.9 2 0 0 2 2 2 1 CS domain MAT1 PF06391.8 EGO53075.1 - 5.9e-30 104.3 5.4 7.3e-30 104.0 3.8 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_3 PF13920.1 EGO53075.1 - 3.3e-05 23.4 6.2 4.8e-05 22.9 4.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO53075.1 - 0.00077 19.0 3.3 0.0017 17.9 2.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO53075.1 - 0.0032 17.4 7.8 0.0058 16.6 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO53075.1 - 0.0056 16.3 8.5 0.014 15.0 6.0 1.7 1 1 1 2 2 2 1 zinc-RING finger domain Atg14 PF10186.4 EGO53075.1 - 0.015 14.2 3.3 0.02 13.8 2.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MRP-S26 PF14943.1 EGO53075.1 - 0.027 14.0 13.9 0.039 13.5 9.6 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 zf-RING_4 PF14570.1 EGO53075.1 - 0.11 12.0 7.9 0.2 11.2 2.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 EGO53075.1 - 0.33 10.8 7.5 0.75 9.6 5.2 1.6 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 EGO53075.1 - 1.4 8.8 5.6 3.9 7.4 3.9 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING ANTH PF07651.11 EGO53076.1 - 7.4e-56 188.8 0.2 9.1e-42 142.6 0.0 2.4 1 1 1 2 2 2 2 ANTH domain ENTH PF01417.15 EGO53076.1 - 5.1e-08 32.8 0.0 9.1e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 ENTH domain tRNA-synt_2 PF00152.15 EGO53077.1 - 1.2e-99 333.3 0.0 1.6e-99 332.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EGO53077.1 - 0.027 14.0 0.2 0.26 10.8 0.1 2.1 1 1 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 EGO53077.1 - 0.057 12.6 0.1 3.9 6.6 0.0 2.6 2 1 0 2 2 2 0 tRNA synthetases class II core domain (F) TFIIA PF03153.8 EGO53078.1 - 8.5 6.1 30.5 15 5.3 21.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_31 PF01055.21 EGO53079.1 - 1.8e-164 547.8 3.4 2.3e-164 547.4 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Rotavirus_VP7 PF05868.6 EGO53079.1 - 0.18 10.9 0.1 0.33 10.0 0.1 1.3 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 Sugar_tr PF00083.19 EGO53081.1 - 2.1e-123 412.2 21.2 2.5e-123 411.9 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO53081.1 - 3.4e-18 65.4 27.7 3.4e-18 65.4 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_2 PF00890.19 EGO53084.1 - 2.1e-85 287.1 0.7 2.8e-85 286.6 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EGO53084.1 - 5.7e-22 77.3 0.3 9.9e-21 73.3 0.0 2.9 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EGO53084.1 - 1.1e-13 50.9 1.6 4.2e-13 48.9 1.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGO53084.1 - 2.8e-09 36.5 1.9 6.6e-09 35.3 0.5 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO53084.1 - 8.7e-09 35.5 0.0 7.7e-07 29.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO53084.1 - 2.8e-08 33.6 2.4 1e-07 31.8 0.3 2.8 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGO53084.1 - 1.2e-06 27.2 1.6 0.0053 15.2 0.2 3.3 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 EGO53084.1 - 9e-05 21.6 1.6 0.013 14.5 0.4 2.5 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 EGO53084.1 - 0.00015 20.9 2.1 0.0004 19.5 1.5 1.6 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EGO53084.1 - 0.00047 19.1 2.8 0.082 11.7 0.6 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 EGO53084.1 - 0.00055 19.1 1.2 0.21 10.6 0.2 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EGO53084.1 - 0.025 14.6 1.6 0.099 12.6 1.1 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO53084.1 - 0.21 12.0 5.6 1.5 9.2 1.0 3.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PAH PF02671.16 EGO53086.1 - 3.2e-40 135.4 2.0 9.4e-18 63.5 0.5 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EGO53086.1 - 1.6e-37 127.3 0.0 5.9e-37 125.4 0.0 2.1 2 0 0 2 2 2 1 Sin3 family co-repressor HEPN PF05168.9 EGO53086.1 - 0.01 15.7 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 HEPN domain Fungal_trans PF04082.13 EGO53088.1 - 1.8e-14 53.2 0.7 3e-14 52.5 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO53088.1 - 5.8e-07 29.3 9.6 1.1e-06 28.3 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF59 PF01883.14 EGO53092.1 - 1.8e-05 24.6 0.0 5.3e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function DUF59 GTP_EFTU PF00009.22 EGO53094.1 - 1.9e-43 148.1 0.0 2.6e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGO53094.1 - 5.1e-27 93.8 0.0 1.6e-26 92.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EGO53094.1 - 1.2e-18 66.7 0.0 3.7e-18 65.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGO53094.1 - 1.6e-08 34.5 0.2 6.3e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EGO53094.1 - 9.6e-07 28.5 0.1 2.5e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EGO53094.1 - 4.3e-05 23.4 0.0 8.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGO53094.1 - 0.0027 18.1 0.0 0.0069 16.8 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Thiolase_N PF00108.18 EGO53095.1 - 9.8e-99 329.6 3.8 1e-98 329.5 2.1 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGO53095.1 - 1.8e-45 153.3 0.9 5e-45 151.9 0.6 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGO53095.1 - 1.2e-05 24.9 1.6 1.9e-05 24.2 0.4 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EGO53095.1 - 0.0028 17.2 5.2 0.01 15.4 0.1 2.9 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III WD40 PF00400.27 EGO53096.1 - 2.8e-14 52.3 1.7 0.00029 20.5 0.1 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat Sel1 PF08238.7 EGO53097.1 - 1.7e-44 149.2 47.5 5.6e-08 33.1 0.2 13.2 14 1 1 15 15 15 9 Sel1 repeat GRP PF07172.6 EGO53097.1 - 0.00037 20.8 1.1 0.00096 19.5 0.8 1.7 1 0 0 1 1 1 1 Glycine rich protein family TPR_17 PF13431.1 EGO53097.1 - 0.037 14.2 6.2 14 6.1 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat tRNA-synt_2c PF01411.14 EGO53101.1 - 6.2e-213 708.0 0.8 2e-212 706.3 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EGO53101.1 - 8.7e-18 63.9 0.3 2e-17 62.7 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EGO53101.1 - 0.00054 19.6 2.0 0.00064 19.3 0.2 2.1 2 0 0 2 2 2 1 DHHA1 domain Methyltransf_28 PF02636.12 EGO53102.1 - 9.6e-35 120.1 0.0 1.9e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 EGO53102.1 - 0.0028 16.6 0.0 0.011 14.6 0.0 1.9 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase PALP PF00291.20 EGO53103.1 - 3.3e-56 190.7 0.6 5.1e-56 190.1 0.4 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IpgD PF05925.7 EGO53103.1 - 0.026 12.7 0.0 0.035 12.3 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD AAA_19 PF13245.1 EGO53103.1 - 0.039 13.6 2.6 5.2 6.8 0.1 3.6 3 0 0 3 3 3 0 Part of AAA domain KRBA1 PF15287.1 EGO53104.1 - 0.096 12.0 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 KRBA1 family repeat TFIIS_M PF07500.9 EGO53105.1 - 2.2e-24 85.7 1.8 2.2e-24 85.7 1.2 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EGO53105.1 - 1.2e-18 66.4 7.0 1.9e-18 65.7 4.1 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EGO53105.1 - 9e-15 53.9 1.4 1.6e-14 53.1 0.5 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DUF2890 PF11081.3 EGO53105.1 - 0.95 9.4 10.7 0.093 12.7 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) ATP-synt_E PF05680.7 EGO53105.1 - 2.1 8.3 8.8 0.35 10.8 0.2 3.0 3 0 0 3 3 3 0 ATP synthase E chain MFS_1 PF07690.11 EGO53106.1 - 4.4e-37 127.6 48.1 9.7e-37 126.4 32.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO53106.1 - 3.8e-05 22.0 20.4 0.00016 20.0 14.1 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1385 PF07136.6 EGO53106.1 - 0.036 13.1 0.3 0.075 12.1 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1385) DUF3318 PF11780.3 EGO53106.1 - 0.072 12.6 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) DUF4448 PF14610.1 EGO53107.1 - 3.5e-34 117.9 0.0 5.1e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 EGO53107.1 - 0.089 13.2 0.7 0.16 12.4 0.1 1.7 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family 2OG-FeII_Oxy PF03171.15 EGO53108.1 - 0.018 15.3 0.0 0.032 14.5 0.0 1.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FRG1 PF06229.7 EGO53109.1 - 2.2e-59 200.1 0.4 2.6e-59 199.8 0.3 1.0 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EGO53109.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.7 1 1 0 1 1 1 0 Fascin domain SRF-TF PF00319.13 EGO53110.1 - 3.9e-24 83.6 0.2 6e-24 83.0 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3591 PF12157.3 EGO53112.1 - 7.8e-190 631.1 0.0 1e-189 630.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EGO53112.1 - 0.0098 15.5 0.5 0.024 14.3 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle D-ser_dehydrat PF14031.1 EGO53113.1 - 4.9e-21 74.7 0.0 2.2e-20 72.6 0.0 2.1 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EGO53113.1 - 4.9e-10 39.3 0.0 7.5e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Actin PF00022.14 EGO53114.1 - 2.2e-146 487.2 0.0 2.5e-146 487.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGO53114.1 - 9.5e-07 27.7 0.0 0.0063 15.1 0.0 2.5 3 0 0 3 3 3 2 MreB/Mbl protein Hydantoinase_A PF01968.13 EGO53114.1 - 0.081 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Vps8 PF12816.2 EGO53115.1 - 2.8e-77 258.4 0.0 5.9e-77 257.3 0.0 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EGO53115.1 - 1.5e-08 34.3 0.3 0.00086 18.9 0.1 3.3 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EGO53115.1 - 0.0013 18.5 0.1 0.0013 18.5 0.1 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EGO53115.1 - 0.055 13.1 0.1 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DUF3752 PF12572.3 EGO53117.1 - 7.1e-44 149.5 8.7 7.1e-44 149.5 6.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) zf-RING_2 PF13639.1 EGO53118.1 - 5.6e-14 51.6 6.6 8.9e-14 51.0 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGO53118.1 - 2.6e-08 33.3 3.8 4.3e-08 32.6 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGO53118.1 - 1.1e-07 31.8 3.7 2.4e-07 30.7 2.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGO53118.1 - 1.4e-06 27.8 3.8 2.3e-06 27.1 2.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGO53118.1 - 1.3e-05 25.0 5.1 2.3e-05 24.3 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO53118.1 - 2.8e-05 23.6 2.3 4.5e-05 23.0 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGO53118.1 - 0.00071 19.3 2.3 0.0016 18.2 1.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGO53118.1 - 0.0033 16.9 6.4 0.0067 15.9 4.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGO53118.1 - 0.023 14.3 0.3 0.063 12.9 0.1 1.9 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 EGO53118.1 - 0.044 13.7 3.6 0.12 12.3 2.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 EGO53118.1 - 0.05 13.3 5.5 0.089 12.4 3.8 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 EGO53118.1 - 0.13 12.3 5.5 0.3 11.1 3.8 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 EGO53118.1 - 0.15 11.9 4.5 0.34 10.8 3.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 EGO53118.1 - 0.64 9.7 8.1 0.13 11.9 1.9 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Raffinose_syn PF05691.7 EGO53119.1 - 4.9e-51 173.1 2.1 6.9e-43 146.2 0.0 2.1 1 1 1 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_31 PF01055.21 EGO53119.1 - 5.7e-05 22.1 0.6 7.9e-05 21.6 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.13 EGO53119.1 - 0.00017 20.4 0.8 0.00024 19.9 0.5 1.2 1 0 0 1 1 1 1 Melibiase Peptidase_M16 PF00675.15 EGO53120.1 - 1.3e-57 193.7 0.4 3.3e-57 192.4 0.3 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGO53120.1 - 1.4e-39 135.6 0.0 3.4e-38 131.1 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF1713 PF08213.6 EGO53121.1 - 2.1e-10 40.0 20.7 2.1e-10 40.0 14.3 2.0 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Thioredoxin_4 PF13462.1 EGO53122.1 - 1.2e-07 31.9 0.0 2.3e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EGO53122.1 - 0.045 13.3 2.3 0.76 9.3 0.2 2.6 1 1 0 2 2 2 0 DSBA-like thioredoxin domain NGP1NT PF08153.7 EGO53123.1 - 3.8e-48 162.7 0.7 6.2e-48 162.0 0.5 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EGO53123.1 - 2.1e-20 72.8 0.0 4e-16 59.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO53123.1 - 2.8e-06 26.7 0.1 4.2e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGO53123.1 - 2.1e-05 24.4 0.6 0.12 12.1 0.0 3.6 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 EGO53123.1 - 0.00028 20.1 0.0 0.0011 18.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EGO53123.1 - 0.0013 18.1 0.0 0.15 11.4 0.0 2.9 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EGO53123.1 - 0.0056 15.9 0.0 3.5 6.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Daxx PF03344.10 EGO53123.1 - 0.95 7.8 25.5 1.5 7.2 17.7 1.2 1 0 0 1 1 1 0 Daxx Family ABC2_membrane PF01061.19 EGO53124.1 - 1e-36 126.0 23.8 1e-36 126.0 16.5 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EGO53124.1 - 2.8e-25 89.2 0.0 4.4e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGO53124.1 - 1.8e-09 37.9 0.0 5.5e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EGO53124.1 - 8e-06 25.1 35.9 4.5e-05 22.6 24.9 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 EGO53124.1 - 2.4e-05 23.8 0.0 0.0039 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain hEGF PF12661.2 EGO53124.1 - 0.0014 18.5 26.3 0.01 15.8 1.7 4.6 4 0 0 4 4 3 2 Human growth factor-like EGF AAA_29 PF13555.1 EGO53124.1 - 0.0027 17.1 0.1 0.0055 16.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGO53124.1 - 0.0066 15.6 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 EGO53124.1 - 0.011 14.8 0.0 1.5 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.14 EGO53124.1 - 0.031 13.5 0.0 0.63 9.2 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EGO53124.1 - 0.038 14.3 0.0 0.089 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGO53124.1 - 0.051 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGO53124.1 - 0.052 13.2 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 EGO53124.1 - 0.064 14.0 0.0 0.16 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGO53124.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EGO53124.1 - 0.09 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGO53124.1 - 0.094 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGO53124.1 - 0.097 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EGO53124.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EGO53124.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.16 EGO53125.1 - 2.7e-36 125.2 0.0 3.5e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGO53125.1 - 6.1e-05 21.9 0.0 9.7e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGO53125.1 - 8.8e-05 20.9 0.0 0.00012 20.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGO53125.1 - 0.0077 15.3 0.1 0.036 13.1 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.2 EGO53125.1 - 0.0093 14.5 0.0 0.013 14.0 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Hexokinase_2 PF03727.11 EGO53126.1 - 2e-87 292.4 0.0 2.8e-87 291.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EGO53126.1 - 4.6e-76 254.7 0.0 4e-75 251.6 0.0 1.9 2 0 0 2 2 2 1 Hexokinase FGGY_N PF00370.16 EGO53126.1 - 0.089 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain PhnJ PF06007.6 EGO53126.1 - 0.18 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ Ribophorin_I PF04597.9 EGO53127.1 - 7.6e-157 522.2 0.0 8.7e-157 522.0 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Pil1 PF13805.1 EGO53128.1 - 1.6e-105 352.1 2.4 1.6e-105 352.1 1.7 1.5 1 1 1 2 2 2 1 Eisosome component PIL1 MSV199 PF10553.4 EGO53128.1 - 0.13 12.1 0.5 6.2 6.6 0.0 2.2 2 0 0 2 2 2 0 MSV199 domain Seryl_tRNA_N PF02403.17 EGO53128.1 - 2.9 7.9 9.3 5.5 7.0 3.1 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MCM PF00493.18 EGO53129.1 - 2.1e-141 470.5 0.0 2.9e-141 470.0 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGO53129.1 - 4.5e-26 91.6 0.0 1.9e-25 89.6 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGO53129.1 - 1.4e-05 24.3 0.0 0.00024 20.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGO53129.1 - 2.1e-05 24.2 0.1 8.7e-05 22.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGO53129.1 - 0.0043 16.6 0.0 0.016 14.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 EGO53129.1 - 0.0092 14.6 0.4 0.015 13.9 0.3 1.2 1 0 0 1 1 1 1 AAA domain Clat_adaptor_s PF01217.15 EGO53130.1 - 7.4e-14 51.6 0.0 2.1e-12 46.9 0.1 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Sua5_yciO_yrdC PF01300.13 EGO53131.1 - 6.4e-52 175.3 0.0 9.8e-52 174.7 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EGO53131.1 - 2.5e-27 95.4 0.0 5.2e-27 94.4 0.0 1.6 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Pkinase PF00069.20 EGO53132.1 - 2.4e-55 187.5 0.0 3.2e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO53132.1 - 2.4e-41 141.5 0.0 3.4e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO53132.1 - 0.00016 20.7 0.0 0.00085 18.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGO53132.1 - 0.029 14.0 0.1 0.52 10.0 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EGO53132.1 - 0.048 12.7 0.0 0.094 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAD_binding_3 PF01494.14 EGO53134.1 - 8.7e-25 87.5 0.0 4.4e-23 81.9 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGO53134.1 - 3.8e-07 29.3 0.2 0.00042 19.3 0.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.5 EGO53134.1 - 6.1e-05 21.9 0.0 9.7e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 EGO53134.1 - 0.00037 19.5 0.1 0.0066 15.4 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EGO53134.1 - 0.0027 17.6 0.0 0.0086 15.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO53134.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 EGO53134.1 - 0.028 13.5 0.0 0.26 10.3 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.9 EGO53134.1 - 0.033 12.8 0.0 1.9 7.0 0.0 2.8 2 1 1 3 3 3 0 Tryptophan halogenase K_oxygenase PF13434.1 EGO53134.1 - 0.058 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGO53134.1 - 0.088 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Complex1_49kDa PF00346.14 EGO53136.1 - 2.2e-135 449.9 0.0 2.9e-135 449.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit RNA_pol_A_bac PF01000.21 EGO53137.1 - 4.6e-27 94.3 0.0 4.1e-26 91.3 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EGO53137.1 - 1.5e-10 40.0 0.0 2.2e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.16 EGO53138.1 - 7.1e-37 126.2 0.4 1.9e-36 124.8 0.1 1.8 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EGO53138.1 - 7.6e-30 102.5 0.1 1.3e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EGO53138.1 - 8.4e-24 82.9 0.3 1.4e-23 82.2 0.2 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EGO53138.1 - 3.1e-14 52.0 1.0 3.1e-14 52.0 0.7 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EGO53138.1 - 1.9e-05 24.6 0.1 0.00013 22.0 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Ecm33 PF12454.3 EGO53138.1 - 0.034 14.0 3.3 0.071 12.9 2.3 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Shikimate_DH PF01488.15 EGO53138.1 - 0.076 13.1 0.1 0.21 11.7 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Telomere_reg-2 PF10193.4 EGO53139.1 - 4.6e-41 139.6 0.0 1.2e-40 138.3 0.0 1.8 1 0 0 1 1 1 1 Telomere length regulation protein COX17 PF05051.8 EGO53140.1 - 4.4e-20 71.4 6.4 5.5e-20 71.1 4.4 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) DegT_DnrJ_EryC1 PF01041.12 EGO53141.1 - 0.00013 21.1 2.1 0.00015 20.8 1.5 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family LUC7 PF03194.10 EGO53141.1 - 0.092 12.2 4.0 0.12 11.9 2.8 1.1 1 0 0 1 1 1 0 LUC7 N_terminus IncA PF04156.9 EGO53141.1 - 0.13 11.8 8.0 0.21 11.1 5.1 1.6 1 1 1 2 2 2 0 IncA protein NAM-associated PF14303.1 EGO53141.1 - 0.13 12.5 4.5 0.21 11.9 3.1 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain NPV_P10 PF05531.7 EGO53141.1 - 0.13 12.4 0.3 1.3 9.3 0.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FUSC-like PF12805.2 EGO53141.1 - 0.15 10.9 4.1 0.19 10.6 2.8 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Med4 PF10018.4 EGO53141.1 - 0.96 8.8 8.5 0.34 10.3 1.6 2.2 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 SLX9 PF15341.1 EGO53141.1 - 1.2 9.6 11.2 0.29 11.5 5.2 1.8 2 1 1 3 3 3 0 Ribosome biogenesis protein SLX9 G-patch PF01585.18 EGO53142.1 - 5e-05 22.9 0.0 0.00017 21.2 0.0 2.0 1 1 0 1 1 1 1 G-patch domain MIP-T3 PF10243.4 EGO53142.1 - 0.072 11.5 75.8 0.12 10.7 52.6 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PLRV_ORF5 PF01690.12 EGO53142.1 - 1.7 7.7 39.2 2.7 7.0 27.2 1.4 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF936 PF06075.7 EGO53142.1 - 4.1 6.2 38.2 5.2 5.8 26.5 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Fungal_trans PF04082.13 EGO53146.1 - 3.2e-05 22.9 0.0 7.6e-05 21.7 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO53146.1 - 0.00028 20.7 13.0 0.00043 20.1 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MerR-DNA-bind PF09278.6 EGO53146.1 - 0.2 12.0 0.2 0.58 10.5 0.1 1.8 1 0 0 1 1 1 0 MerR, DNA binding RhoGAP PF00620.22 EGO53147.1 - 3.7e-43 146.7 0.0 8.3e-43 145.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EGO53147.1 - 2.4e-12 46.9 0.0 5.5e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EGO53147.1 - 1.6e-06 28.3 0.0 4.7e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain DUF3450 PF11932.3 EGO53147.1 - 0.015 14.5 2.8 0.03 13.5 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PH_8 PF15409.1 EGO53147.1 - 0.02 14.9 0.0 0.088 12.8 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain MFS_1 PF07690.11 EGO53148.1 - 9.6e-32 110.0 56.9 2.2e-27 95.6 22.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGO53148.1 - 0.00015 20.1 2.7 0.0014 16.9 1.0 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) PITH PF06201.8 EGO53150.1 - 2.1e-45 154.2 0.0 2.9e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EGO53150.1 - 5.1e-08 32.5 0.0 1.1e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin DIM1 PF02966.11 EGO53150.1 - 0.027 13.9 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF1777 PF08648.7 EGO53151.1 - 0.00034 20.4 24.1 0.00034 20.4 16.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) PRA1 PF03208.14 EGO53153.1 - 1.2e-43 148.1 0.4 1.5e-43 147.8 0.3 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF4260 PF14079.1 EGO53153.1 - 0.053 13.3 2.8 0.083 12.7 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4260) DPPIV_N PF00930.16 EGO53156.1 - 5.4e-110 367.3 1.6 7.4e-110 366.8 1.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EGO53156.1 - 1.7e-57 194.1 2.0 3e-57 193.2 1.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO53156.1 - 9.5e-10 38.4 0.1 2.4e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO53156.1 - 1e-08 35.3 0.1 1.8e-07 31.3 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EGO53156.1 - 4.3e-08 32.9 1.9 1.3e-06 28.1 0.5 2.5 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EGO53156.1 - 0.016 14.5 0.0 0.11 11.7 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EGO53156.1 - 0.028 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EGO53156.1 - 0.06 12.7 0.0 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.8 EGO53156.1 - 0.074 11.3 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Mitovir_RNA_pol PF05919.6 EGO53156.1 - 0.095 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase ATP-synt_ab PF00006.20 EGO53157.1 - 4.5e-70 235.4 0.0 7.2e-70 234.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGO53157.1 - 1.1e-26 93.5 0.3 7.9e-26 90.7 0.2 2.4 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGO53157.1 - 1.1e-15 57.6 2.7 2.6e-15 56.3 1.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EGO53157.1 - 0.006 16.4 1.0 0.015 15.2 0.5 1.9 2 0 0 2 2 2 1 HAS barrel domain Arch_ATPase PF01637.13 EGO53157.1 - 0.03 14.0 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Carb_kinase PF01256.12 EGO53158.1 - 4.7e-54 183.2 0.2 7.1e-54 182.6 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EGO53158.1 - 4.5e-05 22.7 0.0 7.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 EGO53158.1 - 0.00042 19.5 0.2 0.0013 17.9 0.1 1.8 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PEP-utilizers PF00391.18 EGO53158.1 - 0.21 11.1 1.1 7.4 6.2 0.0 2.7 3 0 0 3 3 3 0 PEP-utilising enzyme, mobile domain QRPTase_C PF01729.14 EGO53160.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Nol1_Nop2_Fmu PF01189.12 EGO53161.1 - 5.8e-100 334.3 0.0 1.1e-99 333.4 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EGO53161.1 - 0.0075 15.8 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO53161.1 - 0.023 15.2 0.0 0.063 13.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EGO53161.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Clathrin PF00637.15 EGO53162.1 - 3.7e-203 665.2 48.5 1.8e-34 118.3 0.8 8.2 9 1 1 10 10 10 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EGO53162.1 - 1.6e-34 117.5 0.5 7.8e-34 115.3 0.3 2.4 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 EGO53162.1 - 1.7e-32 109.4 2.0 1.8e-05 24.6 0.0 7.6 7 0 0 7 7 7 6 Clathrin propeller repeat TPR_12 PF13424.1 EGO53162.1 - 7.7e-05 22.5 5.9 3.5 7.6 0.0 6.7 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGO53162.1 - 0.00011 21.7 8.9 9.4 6.3 0.1 8.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGO53162.1 - 0.036 14.6 14.5 71 4.4 0.0 8.9 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGO53162.1 - 0.039 13.5 5.4 20 4.9 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2191 PF09957.4 EGO53162.1 - 0.046 13.5 0.1 0.66 9.8 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2191) Ank_3 PF13606.1 EGO53162.1 - 0.05 13.8 0.0 1.1 9.6 0.0 3.5 3 0 0 3 3 2 0 Ankyrin repeat PPR PF01535.15 EGO53162.1 - 0.085 12.8 1.7 40 4.5 0.0 5.1 5 0 0 5 5 5 0 PPR repeat Clathrin-link PF09268.5 EGO53162.1 - 6.7 5.8 9.4 1.7 7.7 2.1 2.9 2 1 0 2 2 2 0 Clathrin, heavy-chain linker Ribosomal_L5_C PF00673.16 EGO53163.1 - 8.2e-22 76.7 0.0 1.2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EGO53163.1 - 1.8e-21 75.6 0.1 4.8e-21 74.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 EGO53164.1 - 4e-18 64.7 0.0 5.9e-18 64.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain MPC PF03650.8 EGO53165.1 - 2.5e-35 121.0 0.1 2.9e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MtN3_slv PF03083.11 EGO53165.1 - 0.031 14.1 0.7 0.04 13.7 0.5 1.2 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange CPSase_L_D2 PF02786.12 EGO53167.1 - 4.4e-81 271.1 0.3 7.4e-81 270.4 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EGO53167.1 - 2.4e-65 219.6 0.0 4.2e-65 218.8 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EGO53167.1 - 5.3e-35 119.8 0.0 1.1e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGO53167.1 - 1.5e-29 102.1 0.0 3.7e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EGO53167.1 - 3.5e-26 92.3 0.0 8.8e-26 91.0 0.0 1.7 1 1 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EGO53167.1 - 1e-19 71.0 0.1 2.3e-19 69.8 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EGO53167.1 - 9.9e-19 66.7 2.1 1.7e-18 65.9 0.5 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EGO53167.1 - 1e-15 57.3 0.0 3.8e-15 55.4 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EGO53167.1 - 1.2e-10 41.1 0.0 2.1e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EGO53167.1 - 4.2e-10 39.1 0.9 4.6e-06 26.1 0.0 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 EGO53167.1 - 1.7e-07 30.7 0.0 3.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EGO53167.1 - 2.5e-06 27.1 0.0 9.5e-06 25.2 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EGO53167.1 - 2.8e-05 24.0 0.0 7.7e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EGO53167.1 - 0.00077 19.7 0.1 3.4 8.0 0.0 3.5 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_2 PF12700.2 EGO53167.1 - 0.0021 17.3 0.0 0.35 9.9 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 EGO53167.1 - 0.0027 17.0 0.1 0.059 12.6 0.0 2.4 2 0 0 2 2 2 1 HlyD family secretion protein DUF2118 PF09891.4 EGO53167.1 - 0.058 13.1 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) DUF1640 PF07798.6 EGO53168.1 - 5.6e-66 221.9 8.9 6.7e-66 221.6 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Lzipper-MIP1 PF14389.1 EGO53168.1 - 0.0041 17.1 3.9 2.8 8.1 0.0 2.7 2 0 0 2 2 2 2 Leucine-zipper of ternary complex factor MIP1 cwf21 PF08312.7 EGO53168.1 - 0.015 15.1 1.9 0.08 12.8 0.7 2.5 2 1 0 2 2 2 0 cwf21 domain Syntaxin PF00804.20 EGO53168.1 - 0.19 11.9 8.2 0.33 11.1 3.8 2.3 1 1 1 2 2 2 0 Syntaxin FTA4 PF13093.1 EGO53168.1 - 6.1 6.2 10.7 12 5.2 7.4 1.5 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Metal_resist PF13801.1 EGO53168.1 - 7.8 6.5 9.7 0.83 9.6 2.9 2.0 2 0 0 2 2 2 0 Heavy-metal resistance DUF605 PF04652.11 EGO53169.1 - 0.52 9.6 15.0 0.59 9.4 10.4 1.1 1 0 0 1 1 1 0 Vta1 like Methyltransf_11 PF08241.7 EGO53170.1 - 1.5e-22 79.9 0.0 3e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO53170.1 - 1.2e-16 60.6 0.0 2e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO53170.1 - 2.3e-14 53.5 0.1 8.2e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO53170.1 - 3.6e-14 52.4 0.0 1.4e-13 50.4 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EGO53170.1 - 4.8e-14 52.3 0.0 7.6e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO53170.1 - 1.5e-12 47.8 0.0 3.3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO53170.1 - 1.2e-09 38.6 0.0 2.8e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO53170.1 - 1e-08 35.2 0.0 4.3e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGO53170.1 - 1.2e-08 34.3 0.0 1.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 EGO53170.1 - 3.5e-07 29.7 0.0 5.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EGO53170.1 - 4.5e-06 26.1 0.1 7.5e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EGO53170.1 - 0.00012 21.2 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 EGO53170.1 - 0.00016 20.8 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_8 PF05148.10 EGO53170.1 - 0.0003 20.4 0.0 0.011 15.3 0.0 2.8 2 1 0 2 2 2 1 Hypothetical methyltransferase RrnaAD PF00398.15 EGO53170.1 - 0.00074 18.6 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.13 EGO53170.1 - 0.00077 18.7 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 EGO53170.1 - 0.0011 18.0 0.0 0.0025 16.8 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase FmrO PF07091.6 EGO53170.1 - 0.0014 17.6 0.0 0.0077 15.2 0.0 2.0 1 1 1 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) PCMT PF01135.14 EGO53170.1 - 0.0021 17.5 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EGO53170.1 - 0.0031 17.2 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EGO53170.1 - 0.062 11.9 0.1 0.15 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) DOT1 PF08123.8 EGO53170.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 DCR PF14047.1 EGO53172.1 - 2e-05 24.7 15.0 6.6 7.1 0.1 5.4 5 0 0 5 5 5 5 Dppa2/4 conserved region zf-DNL PF05180.7 EGO53173.1 - 2.7e-28 97.4 0.9 5.1e-28 96.5 0.6 1.5 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.8 EGO53173.1 - 0.011 15.3 1.8 0.015 14.9 0.3 1.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-CSL PF05207.8 EGO53173.1 - 0.085 12.3 0.4 0.17 11.4 0.2 1.4 1 0 0 1 1 1 0 CSL zinc finger zinc_ribbon_5 PF13719.1 EGO53173.1 - 0.14 11.7 1.3 1.4 8.5 0.2 2.8 2 1 1 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGO53173.1 - 0.16 11.6 1.3 1.3 8.8 0.2 2.7 2 1 1 3 3 3 0 zinc-ribbon domain PAT1 PF09770.4 EGO53173.1 - 0.17 10.0 6.7 0.19 9.9 4.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 4HBT_3 PF13622.1 EGO53173.1 - 1.7 8.2 7.2 0.15 11.7 1.7 1.6 2 0 0 2 2 2 0 Thioesterase-like superfamily Trypan_PARP PF05887.6 EGO53173.1 - 3.3 7.5 9.5 5.7 6.7 1.0 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Cullin PF00888.17 EGO53174.1 - 7.6e-130 434.2 3.2 9.8e-130 433.8 2.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EGO53174.1 - 9.3e-27 92.6 0.3 2.8e-26 91.1 0.2 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain DNA_pol_phi PF04931.8 EGO53175.1 - 3.6e-59 200.3 29.5 3.6e-40 137.5 18.8 2.5 2 0 0 2 2 2 2 DNA polymerase phi Uteroglobin PF01099.12 EGO53175.1 - 0.02 14.6 0.2 0.12 12.1 0.0 2.5 2 0 0 2 2 2 0 Uteroglobin family XPC-binding PF09280.6 EGO53175.1 - 0.033 13.6 0.0 0.24 10.9 0.0 2.5 2 0 0 2 2 2 0 XPC-binding domain EB1 PF03271.12 EGO53175.1 - 0.16 12.0 0.4 0.8 9.8 0.0 2.5 2 0 0 2 2 2 0 EB1-like C-terminal motif Vps35 PF03635.12 EGO53175.1 - 1.1 7.2 7.0 0.3 9.1 1.2 2.3 3 0 0 3 3 3 0 Vacuolar protein sorting-associated protein 35 Rhodanese PF00581.15 EGO53176.1 - 1.9e-11 44.3 0.0 4.7e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain CwfJ_C_1 PF04677.10 EGO53177.1 - 5.2e-26 90.6 0.0 8.7e-26 89.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EGO53177.1 - 6.4e-24 84.2 0.1 1.4e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 YukC PF10140.4 EGO53177.1 - 0.18 10.3 0.0 0.29 9.6 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DRIM PF07539.7 EGO53178.1 - 9.9e-36 122.2 0.0 3.7e-35 120.3 0.0 2.1 1 0 0 1 1 1 1 Down-regulated in metastasis Proteasome PF00227.21 EGO53179.1 - 1.9e-46 157.7 0.1 2.3e-31 108.5 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EGO53179.1 - 5.9e-13 47.8 0.7 8.8e-13 47.3 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature MelC1 PF06236.6 EGO53180.1 - 0.039 13.9 0.4 0.075 13.0 0.0 1.7 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 DnaJ PF00226.26 EGO53181.1 - 4.2e-19 68.0 0.3 8.2e-19 67.1 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 EGO53181.1 - 0.022 14.7 0.3 0.051 13.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DnaJ PF00226.26 EGO53182.1 - 3.6e-12 45.8 1.2 9.2e-12 44.5 0.8 1.7 1 0 0 1 1 1 1 DnaJ domain Mito_fiss_reg PF05308.6 EGO53182.1 - 1.2 8.4 11.1 0.029 13.7 1.9 2.4 3 0 0 3 3 3 0 Mitochondrial fission regulator Metal_resist PF13801.1 EGO53182.1 - 2 8.4 11.4 2.3 8.2 1.5 3.7 4 0 0 4 4 4 0 Heavy-metal resistance RNA_ligase PF09414.5 EGO53183.1 - 4.3e-35 121.2 0.1 1e-34 119.9 0.0 1.6 2 0 0 2 2 2 1 RNA ligase AP_endonuc_2 PF01261.19 EGO53185.1 - 0.029 13.6 0.0 0.037 13.3 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel zf-C2H2 PF00096.21 EGO53186.1 - 0.00093 19.4 2.4 0.00093 19.4 1.6 3.3 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO53186.1 - 8.9 6.9 10.7 0.14 12.5 0.5 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Ank_2 PF12796.2 EGO53187.1 - 3.4e-13 49.7 0.0 4.3e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGO53187.1 - 6.1e-11 41.5 4.3 0.0011 18.6 0.2 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EGO53187.1 - 9.1e-11 40.9 0.5 0.0062 16.6 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EGO53187.1 - 1.9e-10 40.9 0.6 0.00051 20.4 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO53187.1 - 3.9e-10 39.6 2.3 0.00089 19.4 0.7 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Erv26 PF04148.8 EGO53187.1 - 0.0012 18.2 0.8 0.0042 16.4 0.0 2.1 2 0 0 2 2 2 1 Transmembrane adaptor Erv26 Herpes_LAMP2 PF06126.6 EGO53187.1 - 0.0068 14.8 0.2 0.01 14.2 0.1 1.2 1 0 0 1 1 1 1 Herpesvirus Latent membrane protein 2 SR-25 PF10500.4 EGO53187.1 - 2.6 7.4 18.6 6.5 6.1 12.9 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AMP-binding PF00501.23 EGO53188.1 - 1e-67 228.4 0.0 1.1e-66 225.0 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO53188.1 - 7e-12 46.1 0.4 2.3e-11 44.4 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4360 PF14273.1 EGO53190.1 - 8.3e-75 250.4 4.6 9.6e-75 250.2 3.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Citrate_synt PF00285.16 EGO53191.1 - 1.1e-103 346.6 0.0 1.3e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Glyco_hydro_98M PF08306.6 EGO53191.1 - 0.045 12.4 0.0 0.069 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 ICL PF00463.16 EGO53192.1 - 9.6e-197 654.3 0.3 1.1e-196 654.1 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EGO53192.1 - 2.4e-11 43.3 0.0 6.5e-11 41.9 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Gln-synt_C PF00120.19 EGO53193.1 - 3.3e-63 213.2 0.0 4.3e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Alpha-amylase PF00128.19 EGO53194.1 - 7.5e-25 87.9 2.5 2.9e-23 82.7 1.7 2.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EGO53194.1 - 4.1e-18 65.7 0.1 7.1e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EGO53194.1 - 2.6e-07 30.2 0.0 5.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGO53194.1 - 2.4e-05 24.5 0.0 5.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGO53194.1 - 0.0083 16.2 0.0 0.027 14.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Big_5 PF13205.1 EGO53194.1 - 0.099 13.2 0.1 0.099 13.2 0.1 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain WD40 PF00400.27 EGO53195.1 - 5e-33 111.7 2.4 8.8e-06 25.4 0.0 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EGO53195.1 - 0.016 14.6 0.0 2.8 7.5 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain ADH_N PF08240.7 EGO53196.1 - 1.4e-31 108.4 0.6 2.5e-31 107.6 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO53196.1 - 1e-27 96.2 0.4 1.6e-27 95.6 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glucokinase PF02685.11 EGO53196.1 - 0.093 11.4 0.6 0.14 10.9 0.4 1.2 1 0 0 1 1 1 0 Glucokinase GDC-P PF02347.11 EGO53197.1 - 6.8e-174 578.5 0.0 4.8e-158 526.3 0.0 2.8 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 EGO53197.1 - 4.8e-07 28.8 0.0 6.8e-05 21.7 0.0 2.4 2 1 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGO53197.1 - 5.8e-06 25.6 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Tom5 PF10642.4 EGO53198.1 - 8.7e-25 86.1 0.5 9.4e-25 86.0 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.1 EGO53199.1 - 5e-46 155.8 0.2 5e-46 155.8 0.2 2.5 3 0 0 3 3 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EGO53199.1 - 5.5e-06 26.5 17.3 7.7e-06 26.1 12.0 1.2 1 0 0 1 1 1 1 Nucleoporin FG repeat region V-SNARE_C PF12352.3 EGO53199.1 - 0.0045 17.0 0.7 1.4 9.0 0.0 2.6 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Nbl1_Borealin_N PF10444.4 EGO53199.1 - 0.062 12.6 0.2 0.2 11.0 0.2 1.9 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Metal_resist PF13801.1 EGO53199.1 - 0.16 11.9 0.3 0.16 11.9 0.2 2.2 3 0 0 3 3 2 0 Heavy-metal resistance FUSC PF04632.7 EGO53199.1 - 0.2 10.0 3.0 0.37 9.1 2.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1423 PF07227.6 EGO53199.1 - 0.65 8.5 5.3 0.93 8.0 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Laminin_II PF06009.7 EGO53199.1 - 0.87 9.3 6.5 7.5 6.3 1.0 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF4208 PF13907.1 EGO53199.1 - 0.95 9.7 6.8 0.72 10.0 0.3 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4208) ApoLp-III PF07464.6 EGO53199.1 - 1.3 9.0 7.5 21 5.1 4.8 2.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) TMF_DNA_bd PF12329.3 EGO53199.1 - 2.4 8.0 11.5 6.8 6.5 0.2 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.6 EGO53199.1 - 2.7 7.4 9.2 1.4 8.3 1.0 3.0 3 0 0 3 3 3 0 Phage minor structural protein GP20 vATP-synt_E PF01991.13 EGO53199.1 - 2.7 7.2 9.2 4.5 6.5 1.7 2.4 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit Bap31 PF05529.7 EGO53199.1 - 3.2 7.1 7.6 15 4.9 5.2 2.1 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like TBPIP PF07106.8 EGO53199.1 - 4.6 6.7 8.6 21 4.6 1.6 2.8 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IMD PF08397.6 EGO53199.1 - 4.8 6.4 7.6 1.1 8.4 0.3 2.1 2 0 0 2 2 2 0 IRSp53/MIM homology domain DivIVA PF05103.8 EGO53199.1 - 6.4 6.8 11.7 0.18 11.8 2.5 2.5 2 1 0 3 3 3 0 DivIVA protein Seryl_tRNA_N PF02403.17 EGO53199.1 - 7.2 6.6 12.3 0.73 9.8 0.9 2.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Spc24 PF08286.6 EGO53199.1 - 8.3 6.1 7.9 5.4 6.7 0.6 2.7 3 0 0 3 3 2 0 Spc24 subunit of Ndc80 CHCH PF06747.8 EGO53200.1 - 4e-10 39.3 15.8 8.5e-09 35.1 3.5 2.6 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 EGO53200.1 - 0.00012 21.7 11.4 0.0062 16.2 0.6 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EGO53200.1 - 3.7 7.6 8.3 9.9 6.2 3.9 2.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CAP PF00188.21 EGO53203.1 - 2.3e-16 60.4 6.7 3.3e-16 59.8 4.6 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF605 PF04652.11 EGO53203.1 - 6.1 6.1 15.0 8.1 5.7 10.4 1.1 1 0 0 1 1 1 0 Vta1 like TRAM_LAG1_CLN8 PF03798.11 EGO53204.1 - 6.5e-49 166.1 18.7 6.5e-49 166.1 12.9 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EGO53204.1 - 2.8e-17 61.9 4.0 3.9e-17 61.4 0.1 2.5 2 0 0 2 2 2 1 TRAM1-like protein RRM_1 PF00076.17 EGO53206.1 - 1e-15 57.1 0.1 4.4e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO53206.1 - 2.1e-09 37.2 0.0 4.5e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO53206.1 - 1.5e-05 24.7 0.0 3.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EGO53207.1 - 3.1e-10 39.5 0.1 0.0013 18.5 0.1 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat IKI3 PF04762.7 EGO53207.1 - 0.1 10.3 0.0 0.14 9.9 0.0 1.1 1 0 0 1 1 1 0 IKI3 family Septin PF00735.13 EGO53209.1 - 6e-107 356.8 0.1 1.3e-106 355.7 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EGO53209.1 - 0.00011 22.1 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGO53209.1 - 0.0003 20.6 3.2 0.17 11.6 0.0 3.0 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EGO53209.1 - 0.0037 16.4 0.2 0.011 14.8 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EGO53209.1 - 0.01 16.2 0.3 0.028 14.8 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 EGO53209.1 - 0.034 14.0 0.3 0.091 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGO53209.1 - 0.045 14.5 3.7 0.19 12.5 0.1 2.8 2 2 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGO53209.1 - 0.049 13.7 0.1 0.17 12.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.11 EGO53209.1 - 0.051 12.6 0.1 0.14 11.2 0.1 1.7 1 1 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.22 EGO53209.1 - 0.08 12.3 0.1 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 EGO53209.1 - 0.16 11.4 2.5 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family OmpH PF03938.9 EGO53209.1 - 0.75 9.7 5.5 1.3 8.9 3.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3653 PF12375.3 EGO53209.1 - 1.3 9.2 7.9 4.2 7.6 0.3 3.3 2 1 1 3 3 3 0 Phage protein V_ATPase_I PF01496.14 EGO53209.1 - 2.2 6.0 3.8 3.5 5.3 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bax1-I PF01027.15 EGO53210.1 - 3e-47 160.8 24.7 3.5e-47 160.6 17.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF368 PF04018.8 EGO53210.1 - 0.078 12.1 13.1 0.23 10.6 6.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF368) Herpes_UL43 PF05072.8 EGO53210.1 - 0.097 11.3 6.9 0.035 12.8 3.0 1.5 1 1 0 1 1 1 0 Herpesvirus UL43 protein PrgI PF12666.2 EGO53210.1 - 2.9 8.0 13.8 0.14 12.3 0.5 2.8 1 1 4 5 5 5 0 PrgI family protein DLIC PF05783.6 EGO53211.1 - 2e-23 82.8 2.8 8.7e-20 70.8 0.2 3.5 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) Thioredox_DsbH PF03190.10 EGO53214.1 - 6.9e-55 185.2 0.0 1.5e-54 184.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Sigma70_r4_2 PF08281.7 EGO53214.1 - 0.063 12.7 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 BAF1_ABF1 PF04684.8 EGO53214.1 - 6.9 5.4 16.4 11 4.6 11.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Haem_bd PF14376.1 EGO53215.1 - 0.04 13.6 0.1 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Haem-binding domain DUF3646 PF12362.3 EGO53215.1 - 0.05 13.5 2.4 0.074 12.9 1.7 1.2 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal YqzL PF14006.1 EGO53215.1 - 0.67 10.1 5.1 1.3 9.3 3.5 1.5 1 0 0 1 1 1 0 YqzL-like protein MFS_1 PF07690.11 EGO53216.1 - 1.3e-06 27.3 14.3 3.3e-05 22.7 8.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EGO53216.1 - 0.23 9.4 1.4 1.7 6.5 0.1 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1772 PF08592.6 EGO53216.1 - 1.6 8.4 4.5 15 5.3 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) UDPGT PF00201.13 EGO53217.1 - 3.7e-21 75.2 0.4 2.8e-20 72.3 0.3 2.1 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EGO53217.1 - 6.6e-08 32.3 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EGO53217.1 - 0.067 12.3 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Lipase_GDSL_2 PF13472.1 EGO53218.1 - 4e-10 40.0 0.2 6.7e-10 39.3 0.2 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGO53218.1 - 9.6e-10 38.6 0.8 4.4e-09 36.5 0.6 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ABC_membrane PF00664.18 EGO53219.1 - 7.9e-63 212.4 19.4 2.4e-31 109.1 2.7 2.5 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGO53219.1 - 1.7e-59 200.0 0.3 6.2e-32 110.7 0.0 3.3 2 1 1 3 3 3 3 ABC transporter SMC_N PF02463.14 EGO53219.1 - 2.8e-12 46.3 4.1 5.9e-05 22.3 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGO53219.1 - 3.8e-10 40.2 0.0 0.016 15.2 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 EGO53219.1 - 1.1e-08 35.3 4.7 0.00013 21.9 0.2 3.1 2 2 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EGO53219.1 - 8.7e-08 31.5 0.9 0.0098 15.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EGO53219.1 - 6.7e-07 28.2 0.1 0.00039 19.1 0.0 3.1 4 0 0 4 4 4 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 EGO53219.1 - 1.1e-06 28.4 2.3 0.046 13.6 0.1 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EGO53219.1 - 7.7e-06 25.1 0.1 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGO53219.1 - 1.1e-05 25.6 0.2 0.28 11.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EGO53219.1 - 6.9e-05 22.3 0.1 0.017 14.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EGO53219.1 - 6.9e-05 23.6 0.0 0.84 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EGO53219.1 - 7.9e-05 22.3 0.1 2.5 7.6 0.1 4.1 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.1 EGO53219.1 - 0.00017 21.9 0.2 0.091 13.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGO53219.1 - 0.0006 19.7 0.1 3.3 7.7 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EGO53219.1 - 0.0012 18.0 0.0 0.032 13.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.12 EGO53219.1 - 0.0033 17.2 0.2 1.1 8.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 EGO53219.1 - 0.013 15.8 0.0 4.2 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EGO53219.1 - 0.014 15.8 0.1 1.9 9.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 EGO53219.1 - 0.014 15.2 0.0 8.1 6.3 0.0 3.3 4 1 0 4 4 2 0 AAA domain MobB PF03205.9 EGO53219.1 - 0.015 14.9 0.2 5.3 6.7 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EGO53219.1 - 0.026 14.2 0.0 9.7 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EGO53219.1 - 0.028 14.3 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EGO53219.1 - 0.066 12.2 0.0 10 5.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EGO53219.1 - 0.18 11.2 1.8 12 5.1 0.1 2.8 2 0 0 2 2 2 0 AAA-like domain Fungal_trans PF04082.13 EGO53220.1 - 2.2e-12 46.4 2.0 2.5e-12 46.2 0.1 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO53220.1 - 0.00055 19.7 5.3 0.0015 18.4 3.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RseC_MucC PF04246.7 EGO53220.1 - 0.04 13.4 1.7 0.11 12.1 1.2 1.7 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC zf-C2H2_jaz PF12171.3 EGO53221.1 - 1.2e-06 28.4 4.4 2e-06 27.7 3.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGO53221.1 - 9.7e-05 22.4 0.8 0.00021 21.3 0.6 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EGO53221.1 - 0.0057 16.9 0.2 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGO53221.1 - 0.015 15.4 0.2 0.021 14.8 0.2 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EGO53221.1 - 0.034 14.5 1.0 0.061 13.6 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF965 PF06135.7 EGO53221.1 - 0.08 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF965) DUF1691 PF07950.6 EGO53222.1 - 5.1e-43 145.4 7.3 3.9e-28 97.5 2.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Herpes_US9 PF06072.6 EGO53222.1 - 0.12 12.1 0.5 0.31 10.8 0.3 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF4482 PF14818.1 EGO53223.1 - 0.054 14.1 0.0 0.088 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Dioxygenase_C PF00775.16 EGO53226.1 - 1.5e-12 47.1 3.0 1e-11 44.4 2.1 2.1 1 1 0 1 1 1 1 Dioxygenase Pex16 PF08610.5 EGO53227.1 - 6.2e-111 370.6 0.1 7.1e-111 370.4 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF4596 PF15363.1 EGO53227.1 - 5.9 6.8 7.9 0.26 11.2 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) bZIP_1 PF00170.16 EGO53228.1 - 5.7 6.9 13.7 31 4.6 9.5 2.2 1 1 0 1 1 1 0 bZIP transcription factor SBF PF01758.11 EGO53229.1 - 5.6e-50 169.3 10.8 5.6e-50 169.3 7.5 2.3 2 1 0 2 2 2 1 Sodium Bile acid symporter family GMC_oxred_N PF00732.14 EGO53230.1 - 4.1e-76 255.9 0.0 5.5e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO53230.1 - 2.2e-36 125.3 0.0 4.9e-36 124.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EGO53230.1 - 4e-06 25.9 0.0 0.005 15.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO53230.1 - 0.0011 17.9 0.2 0.86 8.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EGO53230.1 - 0.0016 17.3 0.1 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EGO53230.1 - 0.012 14.6 0.0 0.038 13.0 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 EGO53230.1 - 0.041 13.7 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Snf7 PF03357.16 EGO53231.1 - 1.6e-05 24.3 26.7 1.6e-05 24.3 18.5 1.6 1 1 1 2 2 2 1 Snf7 NRDE PF05742.7 EGO53231.1 - 0.052 12.8 2.9 0.069 12.4 2.0 1.1 1 0 0 1 1 1 0 NRDE protein DUF427 PF04248.7 EGO53232.1 - 3.8e-24 84.1 0.3 4.8e-24 83.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) bZIP_2 PF07716.10 EGO53233.1 - 1.2e-08 34.6 15.9 1.2e-08 34.6 11.0 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EGO53233.1 - 0.0022 17.9 14.2 0.0045 16.9 9.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor Adaptin_binding PF10199.4 EGO53233.1 - 0.05 13.8 4.2 0.17 12.1 0.2 2.7 3 0 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 DSHCT PF08148.7 EGO53234.1 - 5.9e-59 198.3 0.3 1.1e-58 197.4 0.2 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EGO53234.1 - 1.3e-20 73.5 0.0 3.1e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO53234.1 - 4.3e-06 26.4 0.8 9.3e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 EGO53234.1 - 0.00048 19.3 0.1 0.0035 16.5 0.0 2.2 1 1 0 1 1 1 1 rRNA-processing arch domain ResIII PF04851.10 EGO53234.1 - 0.016 15.0 0.4 0.45 10.3 0.0 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Swi3 PF07962.7 EGO53235.1 - 1.2e-29 101.7 0.1 2.2e-29 100.9 0.1 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 NADH-u_ox-rdase PF10785.4 EGO53236.1 - 7.4e-36 122.2 0.3 1.2e-35 121.6 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EGO53236.1 - 7.7e-33 112.0 0.0 1.2e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit ATP-grasp_3 PF02655.9 EGO53237.1 - 0.00048 20.0 0.0 0.0014 18.4 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EGO53237.1 - 0.0026 17.5 0.0 0.0069 16.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGO53237.1 - 0.064 11.9 0.0 0.14 10.8 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EGO53237.1 - 0.065 12.5 0.2 0.27 10.5 0.1 1.9 1 1 0 1 1 1 0 ATP-grasp domain adh_short PF00106.20 EGO53239.1 - 1.2e-23 83.8 3.5 1.6e-22 80.2 2.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO53239.1 - 1.6e-20 73.9 1.8 3.2e-20 72.9 1.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO53239.1 - 6.6e-09 35.6 2.5 4.2e-08 33.0 0.2 2.2 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 EGO53239.1 - 5.1e-06 26.6 0.2 1.2e-05 25.4 0.1 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EGO53239.1 - 0.0015 18.5 0.6 0.0048 16.9 0.4 2.1 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EGO53239.1 - 0.018 14.0 0.2 0.028 13.3 0.2 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase ADH_zinc_N PF00107.21 EGO53239.1 - 0.027 14.0 0.1 0.059 12.9 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.16 EGO53239.1 - 0.044 13.1 0.9 0.16 11.3 0.6 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 EGO53239.1 - 0.057 12.8 0.1 0.14 11.5 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_7 PF13241.1 EGO53239.1 - 0.06 13.6 0.7 0.31 11.3 0.3 2.1 2 1 0 2 2 2 0 Putative NAD(P)-binding SWIRM PF04433.12 EGO53240.1 - 5.6e-16 58.4 0.1 1.9e-14 53.5 0.0 2.4 2 0 0 2 2 2 1 SWIRM domain Atrophin-1 PF03154.10 EGO53241.1 - 0.089 10.9 0.3 0.097 10.7 0.2 1.0 1 0 0 1 1 1 0 Atrophin-1 family F-box-like PF12937.2 EGO53243.1 - 1.8e-09 37.1 0.4 3.2e-09 36.3 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO53243.1 - 8.6e-08 31.6 0.3 1.9e-07 30.5 0.2 1.5 1 0 0 1 1 1 1 F-box domain SGL PF08450.7 EGO53244.1 - 1.5e-24 86.7 0.4 2.3e-24 86.1 0.3 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EGO53244.1 - 4.4e-06 26.6 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 EGO53244.1 - 4e-05 23.5 0.1 0.0024 17.8 0.0 3.2 3 0 0 3 3 3 1 Arylesterase NHL PF01436.16 EGO53244.1 - 0.0002 21.1 4.9 0.14 12.1 0.0 3.7 3 0 0 3 3 3 2 NHL repeat Glyco_hydro_61 PF03443.9 EGO53245.1 - 4.3e-59 199.9 0.0 6e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EGO53245.1 - 4.1e-09 35.9 16.6 4.1e-09 35.9 11.5 3.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Sugar_tr PF00083.19 EGO53246.1 - 6.4e-80 268.9 20.0 7.4e-80 268.7 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO53246.1 - 1.2e-16 60.4 34.8 4.3e-12 45.4 14.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily EBP PF05241.7 EGO53246.1 - 2.2 7.2 9.2 0.13 11.2 0.6 2.4 2 0 0 2 2 2 0 Emopamil binding protein Enolase_C PF00113.17 EGO53248.1 - 3.4e-117 390.6 0.0 4.2e-117 390.3 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EGO53248.1 - 3.9e-52 175.6 0.0 6.2e-52 175.0 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EGO53248.1 - 0.016 15.1 0.1 0.045 13.7 0.0 1.8 2 0 0 2 2 2 0 Enolase C-terminal domain-like HLH PF00010.21 EGO53249.1 - 4e-18 64.8 0.1 6.8e-18 64.1 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.16 EGO53249.1 - 0.029 14.3 0.5 0.083 12.8 0.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor MRI PF15325.1 EGO53249.1 - 7.8 7.5 7.4 14 6.6 4.4 2.0 2 0 0 2 2 2 0 Modulator of retrovirus infection CXCR4_N PF12109.3 EGO53254.1 - 0.14 11.9 2.7 0.38 10.5 1.9 1.7 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal Herpes_LMP2 PF07415.6 EGO53254.1 - 0.27 9.8 5.4 0.39 9.2 3.8 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein U79_P34 PF03064.11 EGO53255.1 - 7.7 5.9 14.9 11 5.4 10.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 GRIP PF01465.15 EGO53257.1 - 1.7e-15 56.1 0.1 3.8e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 GRIP domain IncA PF04156.9 EGO53257.1 - 3.8e-06 26.6 106.6 0.011 15.3 20.4 5.5 2 2 3 5 5 5 3 IncA protein AAA_27 PF13514.1 EGO53257.1 - 1.2e-05 23.2 86.8 0.00038 18.3 25.6 2.4 2 0 0 2 2 2 2 AAA domain ATG16 PF08614.6 EGO53257.1 - 4.5e-05 23.3 98.4 0.015 15.1 9.9 6.4 2 2 4 6 6 6 4 Autophagy protein 16 (ATG16) MscS_porin PF12795.2 EGO53257.1 - 0.00011 21.6 102.3 0.0057 16.0 19.4 5.8 2 2 4 6 6 6 4 Mechanosensitive ion channel porin domain GAS PF13851.1 EGO53257.1 - 0.00017 20.8 98.4 0.0058 15.8 17.4 6.2 2 2 2 5 5 5 4 Growth-arrest specific micro-tubule binding WEMBL PF05701.6 EGO53257.1 - 0.00058 18.4 52.2 0.00058 18.4 36.2 3.4 2 1 1 3 3 3 2 Weak chloroplast movement under blue light AAA_13 PF13166.1 EGO53257.1 - 0.0017 16.9 22.1 0.0017 16.9 15.3 4.4 2 2 2 4 4 4 3 AAA domain Tropomyosin_1 PF12718.2 EGO53257.1 - 0.0017 18.2 23.5 0.0017 18.2 16.3 6.3 2 2 4 6 6 6 2 Tropomyosin like Phage_GP20 PF06810.6 EGO53257.1 - 0.0026 17.1 9.2 0.0026 17.1 6.4 8.1 2 2 6 8 8 8 2 Phage minor structural protein GP20 Reo_sigmaC PF04582.7 EGO53257.1 - 0.0035 16.5 33.3 0.2 10.7 2.2 4.5 2 2 3 5 5 5 4 Reovirus sigma C capsid protein DUF4200 PF13863.1 EGO53257.1 - 0.0039 17.1 19.2 0.0039 17.1 13.3 7.1 3 2 4 7 7 7 1 Domain of unknown function (DUF4200) ERM PF00769.14 EGO53257.1 - 0.0064 16.0 20.4 0.0064 16.0 14.1 4.6 2 2 2 4 4 4 1 Ezrin/radixin/moesin family Nup54 PF13874.1 EGO53257.1 - 0.0067 16.0 17.3 0.0067 16.0 12.0 6.2 2 2 5 7 7 7 1 Nucleoporin complex subunit 54 HOOK PF05622.7 EGO53257.1 - 0.0068 14.2 95.5 0.004 15.0 19.2 4.0 2 2 0 3 3 3 2 HOOK protein LPP PF04728.8 EGO53257.1 - 0.016 15.0 0.1 0.016 15.0 0.1 5.7 5 2 1 6 6 4 0 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.4 EGO53257.1 - 0.92 9.3 119.1 0.15 11.8 14.9 6.4 2 2 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.5 EGO53257.1 - 1.9 8.6 59.7 1.3 9.0 6.0 5.7 4 1 2 6 6 5 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 EGO53257.1 - 4 7.7 42.2 8.7 6.6 1.7 6.8 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein DUF2296 PF10058.4 EGO53258.1 - 5.9e-21 73.9 0.2 1.2e-20 72.9 0.1 1.6 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) zf-RanBP PF00641.13 EGO53258.1 - 0.75 8.9 3.3 0.95 8.6 0.3 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF3439 PF11921.3 EGO53259.1 - 0.011 15.4 1.6 0.011 15.4 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Xan_ur_permease PF00860.15 EGO53261.1 - 3.3e-24 85.1 31.9 9.5e-16 57.2 8.9 2.6 3 0 0 3 3 3 2 Permease family Sulfate_transp PF00916.15 EGO53261.1 - 1.7e-05 24.0 6.7 0.00066 18.7 2.8 2.7 1 1 1 2 2 2 2 Sulfate transporter family BAR PF03114.13 EGO53262.1 - 8.6e-15 54.8 0.1 1.4e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EGO53262.1 - 2.5e-12 46.0 0.1 4.1e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGO53262.1 - 2.3e-10 39.8 0.0 4.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGO53262.1 - 2.8e-10 39.5 0.1 5.1e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_M3_N PF08439.5 EGO53262.1 - 0.22 11.5 1.0 0.85 9.7 0.2 2.2 2 0 0 2 2 2 0 Oligopeptidase F DUF2439 PF10382.4 EGO53263.1 - 4.6e-28 97.2 0.2 8.8e-28 96.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Zn_clus PF00172.13 EGO53265.1 - 0.053 13.4 9.1 0.091 12.6 6.3 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain dCMP_cyt_deam_1 PF00383.17 EGO53266.1 - 8.6e-22 76.7 0.0 2e-21 75.5 0.0 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EGO53266.1 - 0.012 15.4 0.8 0.057 13.2 0.1 2.4 1 1 1 2 2 2 0 Bd3614-like deaminase Y_phosphatase3 PF13350.1 EGO53267.1 - 2.9e-36 125.2 0.0 7.7e-35 120.5 0.0 2.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGO53267.1 - 1.6e-14 53.7 0.3 2.9e-14 52.9 0.2 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EGO53267.1 - 7.7e-05 22.1 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EGO53267.1 - 0.0017 17.7 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family ProSAAS PF07259.7 EGO53267.1 - 0.042 13.3 0.6 0.097 12.1 0.1 1.8 2 0 0 2 2 2 0 ProSAAS precursor PTPlike_phytase PF14566.1 EGO53267.1 - 0.075 13.0 0.1 0.73 9.8 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate MARVEL PF01284.18 EGO53268.1 - 0.00017 21.4 15.6 0.00049 19.9 9.6 2.0 1 1 1 2 2 2 1 Membrane-associating domain VIT1 PF01988.14 EGO53268.1 - 0.014 14.9 0.6 0.014 14.9 0.4 2.0 1 1 1 2 2 2 0 VIT family DUF898 PF05987.8 EGO53268.1 - 0.024 13.5 6.6 0.26 10.1 1.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF805 PF05656.9 EGO53268.1 - 0.22 11.3 9.1 1.6 8.5 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF805) Tetraspannin PF00335.15 EGO53268.1 - 0.38 10.0 9.1 0.87 8.8 6.3 1.6 1 1 0 1 1 1 0 Tetraspanin family FtsL PF04999.8 EGO53268.1 - 0.69 9.6 3.5 0.45 10.2 0.4 2.1 2 0 0 2 2 2 0 Cell division protein FtsL FA_desaturase PF00487.19 EGO53268.1 - 1.3 8.4 12.4 0.7 9.2 6.8 1.6 1 1 1 2 2 2 0 Fatty acid desaturase DUF3784 PF12650.2 EGO53268.1 - 5 7.1 7.7 1.6 8.7 0.8 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) Bot1p PF12298.3 EGO53270.1 - 4.3e-53 179.7 1.6 7e-53 179.0 1.1 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Response_reg PF00072.19 EGO53271.1 - 4e-20 71.9 0.0 3.5e-13 49.5 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain AAA_10 PF12846.2 EGO53272.1 - 1e-09 38.3 0.0 7.1e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EGO53272.1 - 0.00037 20.0 0.0 0.0035 16.8 0.0 2.2 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EGO53272.1 - 0.0074 16.4 0.0 0.96 9.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGO53272.1 - 0.038 13.0 0.0 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.13 EGO53272.1 - 0.066 12.6 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EGO53272.1 - 0.082 12.8 0.1 0.75 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.12 EGO53272.1 - 0.16 11.7 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF2052 PF09747.4 EGO53273.1 - 3.4e-26 92.2 1.3 7.5e-25 87.8 0.9 2.1 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) OPT PF03169.10 EGO53275.1 - 0.072 11.4 0.1 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein HAMP PF00672.20 EGO53275.1 - 0.1 12.7 0.0 0.33 11.1 0.0 1.8 1 0 0 1 1 1 0 HAMP domain Glyco_hydro_43 PF04616.9 EGO53276.1 - 3.3e-28 98.6 1.8 9.9e-19 67.5 0.4 2.7 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 Lipase_3 PF01764.20 EGO53277.1 - 1e-15 57.5 0.0 1.5e-14 53.7 0.0 2.4 1 1 0 1 1 1 1 Lipase (class 3) Acetyltransf_1 PF00583.19 EGO53278.1 - 2.6e-10 40.1 0.0 3.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGO53278.1 - 6.6e-09 35.8 0.0 9.2e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 EGO53280.1 - 3.5e-11 43.4 0.4 6.2e-11 42.6 0.1 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO53280.1 - 6.2e-09 35.7 0.1 1.1e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EGO53280.1 - 5.5e-08 31.7 0.0 5.2e-06 25.2 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 EGO53280.1 - 6.9e-05 22.1 0.1 0.00014 21.1 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EGO53280.1 - 0.00055 19.4 1.7 0.00064 19.2 0.2 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.4 EGO53280.1 - 0.0068 15.6 0.1 0.017 14.3 0.1 1.6 2 0 0 2 2 2 1 Esterase PHB depolymerase Ndr PF03096.9 EGO53280.1 - 0.041 12.3 0.0 0.15 10.4 0.1 1.7 1 1 0 2 2 2 0 Ndr family DLH PF01738.13 EGO53280.1 - 0.047 12.9 0.0 0.12 11.5 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EGO53280.1 - 0.051 13.1 0.1 0.95 8.9 0.0 2.5 3 0 0 3 3 3 0 alpha/beta hydrolase fold adh_short PF00106.20 EGO53281.1 - 5.8e-31 107.6 0.4 8.6e-31 107.1 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO53281.1 - 7.4e-23 81.5 0.0 1.1e-22 80.9 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO53281.1 - 9.2e-15 54.7 0.4 2.2e-14 53.5 0.3 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO53281.1 - 1.8e-05 24.3 0.0 2.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGO53281.1 - 2.5e-05 23.9 0.3 5.2e-05 22.9 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EGO53281.1 - 0.0014 18.6 1.0 0.0057 16.6 0.3 2.1 2 1 1 3 3 3 1 NADH(P)-binding NmrA PF05368.8 EGO53281.1 - 0.0055 15.9 0.3 0.055 12.7 0.2 2.5 2 1 0 2 2 2 1 NmrA-like family 2-Hacid_dh_C PF02826.14 EGO53281.1 - 0.085 12.0 0.0 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EGO53281.1 - 0.18 10.6 0.5 0.3 9.9 0.1 1.6 2 1 0 2 2 2 0 RmlD substrate binding domain ADH_N PF08240.7 EGO53282.1 - 8.5e-20 70.5 0.5 5e-18 64.8 0.4 2.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO53282.1 - 7.1e-16 57.9 0.2 1.2e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aldo_ket_red PF00248.16 EGO53283.1 - 6.7e-54 182.6 0.0 8.5e-54 182.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.8 EGO53283.1 - 0.043 13.0 0.0 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family SNARE PF05739.14 EGO53284.1 - 2.4e-18 65.5 4.2 1.1e-17 63.3 0.6 2.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EGO53284.1 - 3.4e-14 52.8 0.1 3.4e-14 52.8 0.1 2.9 3 1 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 EGO53284.1 - 0.0027 17.2 0.8 0.0027 17.2 0.6 2.3 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Peripla_BP_2 PF01497.13 EGO53284.1 - 0.0031 16.6 0.5 0.0057 15.8 0.4 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Spc7 PF08317.6 EGO53284.1 - 0.008 14.8 1.7 0.008 14.8 1.2 2.1 2 0 0 2 2 2 1 Spc7 kinetochore protein Syntaxin-18_N PF10496.4 EGO53284.1 - 0.0094 15.7 0.1 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus NPV_P10 PF05531.7 EGO53284.1 - 0.021 15.0 2.8 14 6.0 0.1 3.6 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EGO53284.1 - 0.049 13.4 0.7 3 7.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 EGO53284.1 - 0.068 13.3 2.5 0.72 10.0 0.0 2.9 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ApoLp-III PF07464.6 EGO53284.1 - 0.073 13.0 3.7 2.8 7.9 0.1 2.4 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.6 EGO53284.1 - 0.22 9.0 1.2 0.61 7.5 0.0 1.9 2 0 0 2 2 2 0 Prominin Spectrin PF00435.16 EGO53284.1 - 1.9 8.8 7.2 3.7 7.8 0.1 3.6 2 2 2 4 4 4 0 Spectrin repeat Rootletin PF15035.1 EGO53284.1 - 3.4 7.5 7.4 69 3.3 5.1 2.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Sec2p PF06428.6 EGO53287.1 - 6.8e-28 96.4 20.8 7.1e-28 96.4 8.6 2.6 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p DUF2046 PF09755.4 EGO53287.1 - 0.0025 16.7 6.5 0.0025 16.7 4.5 2.2 1 1 1 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) DUF3584 PF12128.3 EGO53287.1 - 4.2 4.5 24.0 6.2 4.0 16.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Pox_A_type_inc PF04508.7 EGO53287.1 - 8.7 6.4 7.6 8.5 6.4 1.7 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Zip PF02535.17 EGO53288.1 - 3.8e-23 81.9 28.7 4.2e-11 42.4 3.1 5.1 2 1 3 5 5 5 3 ZIP Zinc transporter Sporozoite_P67 PF05642.6 EGO53289.1 - 0.29 8.9 5.6 0.34 8.7 3.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2796 PF10986.3 EGO53289.1 - 0.39 10.6 8.2 0.51 10.2 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Pkinase PF00069.20 EGO53292.1 - 1.1e-37 129.5 0.0 1.7e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO53292.1 - 4.8e-16 58.6 0.0 9.5e-16 57.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO53292.1 - 9.6e-05 21.4 0.0 0.00021 20.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EGO53292.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family LEDGF PF11467.3 EGO53294.1 - 0.035 13.8 0.6 0.051 13.2 0.1 1.5 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) MAT1 PF06391.8 EGO53296.1 - 1.3 8.5 6.2 1.4 8.4 4.3 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Aldo_ket_red PF00248.16 EGO53297.1 - 5.2e-68 228.9 0.0 5.9e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GST_N_3 PF13417.1 EGO53298.1 - 1.4e-08 34.8 0.1 2.6e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO53298.1 - 1.2e-06 28.2 0.0 2.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGO53298.1 - 9.7e-06 25.5 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGO53298.1 - 0.00031 21.1 0.0 0.00055 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO53298.1 - 0.0009 19.1 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF384 PF04064.8 EGO53302.1 - 0.098 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF384) Pyr_redox_3 PF13738.1 EGO53304.1 - 1.3e-25 90.7 0.0 4e-25 89.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGO53304.1 - 1.6e-14 53.0 0.0 4.6e-14 51.5 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EGO53304.1 - 2e-11 43.7 0.0 2.2e-08 33.9 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EGO53304.1 - 1.9e-06 27.0 0.7 5.2e-05 22.3 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EGO53304.1 - 1.5e-05 24.2 0.0 0.00099 18.2 0.0 2.6 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 EGO53304.1 - 2.8e-05 23.1 0.1 0.077 11.8 0.0 4.0 3 1 1 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGO53304.1 - 0.00011 22.5 0.0 0.027 14.8 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EGO53304.1 - 0.00042 19.5 0.0 0.0097 15.0 0.0 2.5 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EGO53304.1 - 0.0069 15.3 0.1 0.13 11.1 0.1 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein Shikimate_DH PF01488.15 EGO53304.1 - 0.0074 16.3 0.0 0.057 13.5 0.0 2.3 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EGO53304.1 - 0.032 14.4 0.0 0.078 13.2 0.0 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 EGO53304.1 - 0.053 13.4 0.0 1.8 8.3 0.0 3.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGO53304.1 - 0.063 12.1 0.1 7.4 5.3 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EGO53304.1 - 0.1 12.3 0.2 36 4.0 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding ApbA PF02558.11 EGO53304.1 - 0.14 11.5 0.0 0.34 10.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NUDIX PF00293.23 EGO53306.1 - 4.9e-18 65.0 0.2 5.8e-18 64.8 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Flu_PA PF00603.12 EGO53306.1 - 0.032 12.2 0.1 0.036 12.1 0.1 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PA Fungal_trans PF04082.13 EGO53307.1 - 1.2e-22 80.1 0.1 1.8e-22 79.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO53307.1 - 3.2e-09 36.5 11.0 5.4e-09 35.8 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_22 PF13401.1 EGO53308.1 - 0.00058 20.0 0.1 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EGO53308.1 - 0.0011 18.7 0.1 0.0029 17.2 0.1 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGO53308.1 - 0.0014 18.6 0.0 0.0043 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGO53308.1 - 0.0019 17.8 0.1 0.0059 16.3 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 EGO53308.1 - 0.0022 17.7 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 NTPase Arch_ATPase PF01637.13 EGO53308.1 - 0.003 17.2 0.0 0.0078 15.9 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase Ank_2 PF12796.2 EGO53308.1 - 0.0054 17.0 0.0 0.2 12.0 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGO53308.1 - 0.037 13.8 0.0 0.64 9.9 0.0 2.9 2 1 0 2 2 2 0 Ankyrin repeat KAP_NTPase PF07693.9 EGO53308.1 - 0.16 10.9 0.2 0.86 8.5 0.1 1.8 1 1 0 2 2 2 0 KAP family P-loop domain DUF2413 PF10310.4 EGO53310.1 - 6.2e-155 516.3 0.0 7.1e-155 516.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 EGO53310.1 - 0.14 12.1 0.4 0.37 10.8 0.3 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain CDC27 PF09507.5 EGO53310.1 - 2.4 7.2 14.8 3.5 6.7 9.7 1.6 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 Med3 PF11593.3 EGO53310.1 - 4.9 6.2 10.7 7.4 5.6 7.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Abhydrolase_6 PF12697.2 EGO53316.1 - 1.6e-31 109.9 0.0 2.1e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO53316.1 - 4e-18 65.8 0.0 2.9e-14 53.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO53316.1 - 1.4e-12 47.6 0.0 3.6e-12 46.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGO53316.1 - 1.8e-05 24.2 0.3 0.0017 17.8 0.1 2.7 2 1 0 2 2 2 1 Putative esterase PGAP1 PF07819.8 EGO53316.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ser_hydrolase PF06821.8 EGO53316.1 - 0.015 14.8 0.0 0.061 12.9 0.0 2.0 3 0 0 3 3 3 0 Serine hydrolase Lipase_3 PF01764.20 EGO53316.1 - 0.038 13.5 0.0 0.16 11.5 0.0 2.0 3 0 0 3 3 3 0 Lipase (class 3) Ndr PF03096.9 EGO53316.1 - 0.054 11.9 0.0 0.093 11.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family Acyl_transf_1 PF00698.16 EGO53316.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase domain Ribosomal_L14 PF00238.14 EGO53317.1 - 3.9e-32 110.5 0.0 4.3e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Malic_M PF03949.10 EGO53318.1 - 1.2e-80 270.7 0.0 1.6e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EGO53318.1 - 5.6e-57 192.2 0.0 1e-56 191.3 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Inhibitor_I53 PF11714.3 EGO53319.1 - 0.1 12.5 0.2 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Glyco_hydro_75 PF07335.6 EGO53321.1 - 1.2e-42 145.4 0.2 1.5e-42 145.0 0.2 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 CFEM PF05730.6 EGO53322.1 - 1.3e-06 28.0 3.2 3.1e-06 26.9 2.2 1.7 1 0 0 1 1 1 1 CFEM domain PspC PF04024.7 EGO53323.1 - 0.14 11.6 2.7 1.4 8.4 0.3 2.1 2 0 0 2 2 2 0 PspC domain Prothymosin PF03247.9 EGO53324.1 - 0.0005 20.1 4.2 0.00064 19.8 2.9 1.2 1 0 0 1 1 1 1 Prothymosin/parathymosin family Cwf_Cwc_15 PF04889.7 EGO53324.1 - 0.13 11.9 4.9 0.14 11.8 3.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.3 EGO53324.1 - 0.14 12.0 6.0 0.16 11.8 4.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF3295 PF11702.3 EGO53324.1 - 0.35 9.8 4.1 0.39 9.6 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) NACHT PF05729.7 EGO53325.1 - 1.6e-10 40.8 0.2 4e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGO53325.1 - 4.4e-06 26.7 0.1 3.5e-05 23.8 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EGO53325.1 - 1.7e-05 24.5 0.0 4.8e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EGO53325.1 - 3.1e-05 24.1 0.5 0.00032 20.8 0.0 3.1 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO53325.1 - 0.00013 22.1 0.0 0.00053 20.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EGO53325.1 - 0.00045 19.1 0.0 0.00085 18.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain PPV_E1_C PF00519.12 EGO53325.1 - 0.001 17.7 0.0 0.0021 16.7 0.0 1.6 1 1 0 1 1 1 1 Papillomavirus helicase AAA_33 PF13671.1 EGO53325.1 - 0.0061 16.4 0.3 0.041 13.7 0.2 2.4 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EGO53325.1 - 0.011 14.6 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Torsin PF06309.6 EGO53325.1 - 0.011 15.5 0.1 0.091 12.6 0.0 2.5 3 0 0 3 3 2 0 Torsin AAA_17 PF13207.1 EGO53325.1 - 0.015 16.0 0.0 0.076 13.8 0.0 2.3 2 0 0 2 2 1 0 AAA domain KTI12 PF08433.5 EGO53325.1 - 0.031 13.4 0.9 0.15 11.2 0.0 2.5 3 1 1 4 4 4 0 Chromatin associated protein KTI12 KAP_NTPase PF07693.9 EGO53325.1 - 0.031 13.2 2.9 8.3 5.2 0.0 3.6 3 1 0 4 4 4 0 KAP family P-loop domain RNA_helicase PF00910.17 EGO53325.1 - 0.04 14.0 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 EGO53325.1 - 0.062 12.8 0.2 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGO53325.1 - 0.11 12.7 0.1 0.37 11.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain ArgK PF03308.11 EGO53325.1 - 0.25 10.0 0.0 1.4 7.6 0.0 1.9 2 0 0 2 2 2 0 ArgK protein SNF2_N PF00176.18 EGO53326.1 - 3.8e-52 176.9 0.0 3e-50 170.7 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGO53326.1 - 7.6e-05 22.6 0.0 0.0025 17.6 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Med12 PF09497.5 EGO53326.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 Transcription mediator complex subunit Med12 E7 PF00527.13 EGO53326.1 - 0.074 13.2 1.1 0.24 11.5 0.8 2.0 1 0 0 1 1 1 0 E7 protein, Early protein AAA_22 PF13401.1 EGO53326.1 - 0.12 12.5 0.0 0.36 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Helicase_C PF00271.26 EGO53327.1 - 3.6e-06 26.7 0.1 4.1e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IBR PF01485.16 EGO53328.1 - 2.5e-11 43.2 15.3 3.1e-07 30.1 1.8 3.8 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 EGO53328.1 - 0.00062 19.7 11.6 0.00062 19.7 8.0 4.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO53328.1 - 0.0034 17.0 11.2 0.0034 17.0 7.7 3.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) RhoGAP PF00620.22 EGO53329.1 - 1.9e-19 69.7 0.0 3.7e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Glyco_hydro_61 PF03443.9 EGO53330.1 - 2.7e-65 220.2 0.3 3.8e-65 219.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EGO53330.1 - 2.9e-12 45.9 11.4 2.9e-12 45.9 7.9 2.8 2 0 0 2 2 2 1 Fungal cellulose binding domain Methyltransf_18 PF12847.2 EGO53331.1 - 0.015 15.8 0.0 0.027 15.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain ketoacyl-synt PF00109.21 EGO53332.1 - 2.6e-71 240.0 0.0 6.5e-71 238.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGO53332.1 - 1e-54 186.0 0.1 1.6e-54 185.4 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EGO53332.1 - 1.8e-51 175.0 0.0 3e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EGO53332.1 - 2.2e-50 170.8 0.3 8.1e-50 168.9 0.0 2.2 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.17 EGO53332.1 - 1.3e-39 134.6 0.3 5e-39 132.8 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EGO53332.1 - 2.2e-37 128.5 3.2 2.6e-37 128.3 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EGO53332.1 - 1.6e-09 38.7 4.3 9.9e-09 36.1 0.2 3.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO53332.1 - 3.9e-06 26.5 0.0 1.9e-05 24.3 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO53332.1 - 1.4e-05 24.6 1.4 0.00035 20.1 0.4 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EGO53332.1 - 7.2e-05 22.9 0.1 0.00018 21.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site DHQS PF01959.11 EGO53332.1 - 0.13 10.9 4.2 0.36 9.4 0.6 2.6 2 0 0 2 2 2 0 3-dehydroquinate synthase (EC 4.6.1.3) Cupin_2 PF07883.6 EGO53333.1 - 5.7e-09 35.3 0.0 1.1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Auxin_BP PF02041.11 EGO53333.1 - 0.059 12.8 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein adh_short_C2 PF13561.1 EGO53334.1 - 2e-27 96.5 2.1 2.4e-27 96.2 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGO53334.1 - 5e-23 81.8 3.6 1.4e-22 80.4 2.5 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO53334.1 - 2.5e-06 27.3 3.6 1.4e-05 24.8 2.4 2.0 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EGO53334.1 - 0.0003 20.8 0.5 0.00056 20.0 0.3 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EGO53334.1 - 0.011 15.5 3.9 0.024 14.4 1.5 2.4 2 1 1 3 3 3 0 ThiF family Trp_syntA PF00290.15 EGO53334.1 - 0.016 13.7 0.0 0.023 13.2 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain 3Beta_HSD PF01073.14 EGO53334.1 - 0.03 13.0 0.2 0.24 10.0 0.2 2.1 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HHH_5 PF14520.1 EGO53334.1 - 0.12 12.5 0.1 0.59 10.3 0.0 2.2 2 1 1 3 3 3 0 Helix-hairpin-helix domain Cupin_2 PF07883.6 EGO53335.1 - 1.5e-05 24.3 0.0 3.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Cupin domain adh_short PF00106.20 EGO53336.1 - 1e-18 67.8 0.1 2.3e-18 66.7 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO53336.1 - 3.8e-11 43.2 0.0 4.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO53336.1 - 0.0034 17.0 0.2 0.0077 15.9 0.1 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO53336.1 - 0.0071 16.3 0.0 0.018 15.0 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding MucB_RseB PF03888.9 EGO53336.1 - 0.078 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 MucB/RseB family adh_short PF00106.20 EGO53337.1 - 3.6e-11 43.2 0.1 6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO53337.1 - 2.3e-07 30.8 0.0 3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Abhydrolase_6 PF12697.2 EGO53338.1 - 1e-29 104.0 0.1 1.4e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO53338.1 - 2.5e-14 53.4 0.0 2.6e-13 50.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO53338.1 - 6.4e-10 38.9 0.0 2e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO53338.1 - 0.0097 15.7 0.0 0.033 14.0 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase FAD_binding_3 PF01494.14 EGO53339.1 - 3.1e-22 79.1 0.0 4.5e-21 75.3 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EGO53339.1 - 3e-07 29.6 0.0 1.3e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EGO53339.1 - 9.7e-07 28.0 0.9 0.015 14.1 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO53339.1 - 1.3e-06 28.6 0.0 3.3e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO53339.1 - 1.2e-05 25.6 0.0 0.0044 17.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO53339.1 - 8.8e-05 21.1 0.0 0.02 13.3 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 EGO53339.1 - 0.00029 20.7 0.0 0.001 19.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGO53339.1 - 0.0031 17.3 0.2 0.8 9.4 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGO53339.1 - 0.017 14.9 0.1 0.04 13.7 0.0 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO53339.1 - 0.038 13.0 0.0 0.092 11.8 0.0 1.6 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 EGO53339.1 - 0.11 12.4 0.1 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_4 PF01565.18 EGO53340.1 - 3.1e-27 94.7 1.4 5.2e-27 94.0 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGO53340.1 - 1.3e-10 40.9 0.1 2.8e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EGO53341.1 - 7.5e-22 77.2 0.1 1.3e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGO53341.1 - 4.7e-07 29.6 0.2 1.2e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Aldo_ket_red PF00248.16 EGO53344.1 - 1.5e-55 188.0 0.0 1.7e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Endosulfine PF04667.12 EGO53346.1 - 7.6e-13 48.2 0.0 2.5e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 cAMP-regulated phosphoprotein/endosulfine conserved region Fungal_trans PF04082.13 EGO53347.1 - 5.3e-16 58.2 0.0 8.1e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO53347.1 - 7.7e-08 32.1 8.2 1.6e-07 31.1 5.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CGI-121 PF08617.5 EGO53348.1 - 2.4e-52 176.8 0.0 3.1e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Pro_dh PF01619.13 EGO53349.1 - 4.9e-32 111.1 0.2 4.1e-30 104.8 0.1 2.9 1 1 0 1 1 1 1 Proline dehydrogenase SHS2_Rpb7-N PF03876.12 EGO53349.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Tim17 PF02466.14 EGO53350.1 - 0.056 13.4 5.1 0.1 12.6 3.5 1.5 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.4 EGO53350.1 - 0.81 9.9 5.3 0.64 10.2 0.2 2.8 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 NEAT PF05031.7 EGO53351.1 - 0.12 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Iron Transport-associated domain Metallophos PF00149.23 EGO53353.1 - 1.1e-06 28.2 7.2 2.8e-06 26.8 3.2 2.7 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Methyltransf_6 PF03737.10 EGO53354.1 - 1.5e-28 99.6 0.0 2.4e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase NIF PF03031.13 EGO53356.1 - 3.8e-38 130.6 0.0 5.4e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Abi_HHR PF07815.9 EGO53357.1 - 0.1 12.7 1.3 0.27 11.3 0.1 2.3 2 0 0 2 2 2 0 Abl-interactor HHR Mito_carr PF00153.22 EGO53359.1 - 3.3e-17 61.9 3.4 2.2e-05 24.0 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Amidase PF01425.16 EGO53360.1 - 0.032 13.0 0.0 0.083 11.7 0.0 1.6 1 1 1 2 2 2 0 Amidase Flavodoxin_1 PF00258.20 EGO53361.1 - 5.3e-11 42.6 0.0 9.1e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 EGO53361.1 - 1.6e-07 30.9 0.0 2.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EGO53361.1 - 2.6e-05 23.8 0.0 3.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EGO53361.1 - 0.062 13.3 0.0 5.8 6.9 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain Bacteriocin_IIc PF10439.4 EGO53361.1 - 8.1 6.6 10.2 13 6.0 3.5 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Yae1_N PF09811.4 EGO53362.1 - 1.5e-12 46.8 2.0 1.5e-12 46.8 1.4 1.9 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Pex14_N PF04695.8 EGO53362.1 - 0.016 15.2 9.8 0.016 15.2 6.8 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hid1 PF12722.2 EGO53362.1 - 0.043 11.4 9.0 0.047 11.3 6.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AAA_23 PF13476.1 EGO53362.1 - 0.069 13.4 13.5 0.097 12.9 9.3 1.3 1 0 0 1 1 1 0 AAA domain Suf PF05843.9 EGO53362.1 - 0.087 12.5 12.8 0.15 11.7 8.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SprA-related PF12118.3 EGO53362.1 - 0.11 11.7 27.7 0.26 10.5 19.2 1.6 1 0 0 1 1 1 0 SprA-related family FimP PF09766.4 EGO53362.1 - 0.14 11.1 23.6 0.28 10.2 16.4 1.5 1 0 0 1 1 1 0 Fms-interacting protein eIF-3_zeta PF05091.7 EGO53362.1 - 0.17 10.5 13.2 0.22 10.0 9.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAA_11 PF13086.1 EGO53362.1 - 0.32 10.5 10.2 0.5 9.9 7.1 1.2 1 0 0 1 1 1 0 AAA domain Peroxin-13_N PF04088.8 EGO53362.1 - 0.34 10.8 2.2 0.75 9.7 1.5 1.6 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Tfb4 PF03850.9 EGO53362.1 - 0.46 9.7 3.2 0.66 9.1 2.2 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 Ycf1 PF05758.7 EGO53362.1 - 0.6 7.7 14.0 0.71 7.5 9.7 1.1 1 0 0 1 1 1 0 Ycf1 PIH1 PF08190.7 EGO53362.1 - 0.81 9.0 17.8 1.3 8.4 12.3 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Cellulose_synt PF03552.9 EGO53362.1 - 2.8 6.1 4.0 3.7 5.7 2.7 1.1 1 0 0 1 1 1 0 Cellulose synthase Borrelia_P83 PF05262.6 EGO53362.1 - 3.1 5.9 15.5 3.5 5.7 10.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Ctr PF04145.10 EGO53362.1 - 3.1 7.8 4.1 8 6.5 2.8 1.8 1 0 0 1 1 1 0 Ctr copper transporter family Herpes_DNAp_acc PF04929.7 EGO53362.1 - 4.2 6.2 11.2 6.8 5.5 7.8 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Folate_carrier PF01770.13 EGO53362.1 - 7 5.0 5.4 12 4.2 3.8 1.4 1 0 0 1 1 1 0 Reduced folate carrier DUF4407 PF14362.1 EGO53362.1 - 8 5.3 15.8 12 4.7 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF913 PF06025.7 EGO53362.1 - 9.1 4.9 7.7 14 4.3 5.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ribosomal_S8 PF00410.14 EGO53364.1 - 1.1e-29 102.9 0.0 1.3e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Iso_dh PF00180.15 EGO53365.1 - 8.5e-100 334.0 0.0 1.2e-99 333.6 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GTP_EFTU PF00009.22 EGO53366.1 - 7.6e-58 195.0 0.0 1.8e-57 193.8 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGO53366.1 - 7.9e-34 115.8 0.0 2.2e-33 114.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 EGO53366.1 - 7.6e-33 112.1 0.0 1.5e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EGO53366.1 - 4.9e-22 77.5 0.0 1.1e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGO53366.1 - 3.8e-12 46.1 0.0 8.9e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF442 PF04273.8 EGO53366.1 - 0.019 14.8 0.0 1.1 9.0 0.0 3.0 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Asp PF00026.18 EGO53367.1 - 2.9e-65 220.6 1.6 3.7e-65 220.2 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO53367.1 - 2e-08 34.3 0.6 1.8e-07 31.2 0.2 2.6 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO53367.1 - 0.00087 19.7 0.4 0.13 12.7 0.3 3.0 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 EGO53367.1 - 0.0014 18.2 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EGO53367.1 - 0.064 13.0 0.0 17 5.3 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease HLH PF00010.21 EGO53368.1 - 5.2e-13 48.4 0.8 1.5e-12 46.9 0.5 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ATG16 PF08614.6 EGO53368.1 - 0.0014 18.4 5.3 0.0014 18.4 3.7 1.9 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF641 PF04859.7 EGO53368.1 - 0.29 10.9 5.7 0.58 9.9 3.9 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Fez1 PF06818.10 EGO53368.1 - 1.2 9.1 9.7 0.079 12.9 1.4 2.3 1 1 1 2 2 2 0 Fez1 IncA PF04156.9 EGO53368.1 - 1.4 8.5 4.9 3.2 7.2 3.4 1.6 1 0 0 1 1 1 0 IncA protein FliJ PF02050.11 EGO53368.1 - 6.6 6.8 10.1 1.3 9.0 4.3 1.8 2 0 0 2 2 2 0 Flagellar FliJ protein DUF4235 PF14019.1 EGO53369.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) RRM_1 PF00076.17 EGO53371.1 - 2.3e-33 113.6 0.1 6.3e-16 57.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO53371.1 - 4e-27 94.0 0.0 7.3e-13 48.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO53371.1 - 1.4e-16 60.0 0.0 1.4e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TerB-C PF15615.1 EGO53371.1 - 0.025 14.8 0.9 0.057 13.6 0.6 1.6 1 0 0 1 1 1 0 TerB-C domain TPR_2 PF07719.12 EGO53372.1 - 2.1e-24 83.4 5.0 8e-07 28.5 0.1 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 EGO53372.1 - 2.9e-24 84.5 8.9 1e-09 37.9 0.7 4.5 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 EGO53372.1 - 9.7e-24 81.9 6.1 8.6e-08 31.4 0.0 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGO53372.1 - 1.6e-19 68.6 5.0 5.6e-06 26.5 0.1 6.4 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGO53372.1 - 8.7e-19 67.6 5.8 6.1e-07 29.9 0.1 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGO53372.1 - 2.5e-18 64.6 3.8 0.001 19.0 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EGO53372.1 - 1.2e-14 52.8 1.6 0.0013 18.3 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGO53372.1 - 5.4e-14 51.8 6.4 2.9e-08 33.5 0.2 4.3 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGO53372.1 - 5.6e-14 50.7 0.2 0.00041 19.9 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO53372.1 - 5.2e-13 49.1 4.9 0.00018 21.7 1.5 4.6 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGO53372.1 - 8.3e-11 41.6 1.8 0.62 10.6 0.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_20 PF14561.1 EGO53372.1 - 4.4e-10 39.5 2.2 0.011 15.7 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGO53372.1 - 2.1e-09 37.1 2.4 0.0009 19.0 0.0 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EGO53372.1 - 1.3e-05 25.2 1.9 0.17 12.0 0.1 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EGO53372.1 - 4.6e-05 22.6 0.6 0.18 10.8 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGO53372.1 - 0.00046 20.0 4.6 0.24 11.3 0.2 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 EGO53372.1 - 0.026 14.3 0.1 5.8 6.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DED PF01335.16 EGO53372.1 - 0.12 12.4 0.1 22 5.2 0.0 2.4 2 0 0 2 2 2 0 Death effector domain TFIIA PF03153.8 EGO53372.1 - 0.17 11.7 6.3 0.32 10.8 4.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNase_T PF00929.19 EGO53373.1 - 9.1e-22 78.0 0.0 6.9e-21 75.2 0.0 2.3 2 0 0 2 2 2 1 Exonuclease SET PF00856.23 EGO53374.1 - 4.1e-10 40.1 0.1 2.5e-09 37.6 0.0 2.5 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 EGO53374.1 - 3.6e-08 33.1 10.9 3.6e-08 33.1 7.6 2.1 2 0 0 2 2 2 1 MYND finger Prefoldin PF02996.12 EGO53375.1 - 2.4e-26 91.7 0.3 3.4e-26 91.2 0.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EGO53375.1 - 0.0023 17.6 2.2 0.46 10.2 0.3 2.1 2 0 0 2 2 2 2 Prefoldin subunit Sec2p PF06428.6 EGO53375.1 - 0.0063 16.3 1.6 0.056 13.2 0.1 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Gp-FAR-1 PF05823.7 EGO53375.1 - 0.089 12.7 0.1 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) K-box PF01486.12 EGO53375.1 - 0.18 11.5 1.1 0.54 10.0 0.1 1.9 2 0 0 2 2 2 0 K-box region KH_1 PF00013.24 EGO53376.1 - 0.0089 15.6 1.5 0.011 15.3 0.2 1.8 2 0 0 2 2 2 1 KH domain DUF3273 PF11677.3 EGO53378.1 - 0.011 15.0 0.7 0.012 14.8 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3273) AAA PF00004.24 EGO53380.1 - 2.7e-14 53.4 0.0 4.7e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGO53380.1 - 1.3e-10 41.6 0.0 8.2e-10 38.9 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO53380.1 - 6.1e-08 32.8 0.0 4.3e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGO53380.1 - 0.00015 22.5 0.0 0.0013 19.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain BAH PF01426.13 EGO53380.1 - 0.00036 20.2 0.0 0.00072 19.2 0.0 1.4 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.1 EGO53380.1 - 0.00085 19.0 0.3 0.0029 17.3 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EGO53380.1 - 0.0059 16.4 0.0 0.65 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGO53380.1 - 0.0092 16.2 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zot PF05707.7 EGO53380.1 - 0.015 14.8 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_11 PF13086.1 EGO53380.1 - 0.036 13.6 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGO53380.1 - 0.036 13.4 0.0 1.8 7.9 0.0 2.4 2 1 1 3 3 3 0 AAA-like domain DUF2075 PF09848.4 EGO53380.1 - 0.039 12.9 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 EGO53380.1 - 0.041 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.1 EGO53380.1 - 0.054 12.1 0.0 0.094 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGO53380.1 - 0.092 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 EGO53380.1 - 0.16 11.6 0.0 1.2 8.7 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase PBP1_TM PF14812.1 EGO53380.1 - 0.24 11.7 7.5 2.1 8.6 1.0 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 EGO53381.1 - 1.4e-52 173.7 15.3 1e-10 41.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGO53381.1 - 0.0018 16.5 4.5 1.9 6.5 0.1 4.2 1 1 4 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EGO53381.1 - 0.058 12.8 0.8 3.4 7.0 0.3 2.8 2 1 0 2 2 2 0 PQQ-like domain Nucleoporin_N PF08801.6 EGO53381.1 - 0.13 11.0 0.0 5.7 5.5 0.0 2.8 2 1 1 3 3 3 0 Nup133 N terminal like Ank_2 PF12796.2 EGO53382.1 - 7e-40 135.2 1.4 4.3e-16 59.0 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGO53382.1 - 3.9e-37 125.4 3.4 2.1e-10 40.5 0.5 5.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGO53382.1 - 6.1e-36 122.1 7.1 9.8e-10 38.6 0.1 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 EGO53382.1 - 9.8e-36 119.8 1.3 1.3e-05 24.7 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.1 EGO53382.1 - 6.1e-31 103.3 0.2 2.8e-05 23.9 0.0 6.5 7 0 0 7 7 7 6 Ankyrin repeat TMF_TATA_bd PF12325.3 EGO53383.1 - 2.3e-40 137.0 15.2 2.3e-40 137.0 10.6 6.9 3 2 5 8 8 8 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EGO53383.1 - 2.2e-18 65.8 20.4 2.2e-18 65.8 14.2 9.8 4 3 6 10 10 10 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 EGO53383.1 - 0.0024 17.7 4.2 0.0024 17.7 2.9 6.4 3 1 2 6 6 6 3 Autophagy protein 16 (ATG16) Filament PF00038.16 EGO53383.1 - 0.0025 17.3 92.8 0.014 14.9 6.0 3.5 2 1 1 3 3 3 2 Intermediate filament protein IncA PF04156.9 EGO53383.1 - 0.0046 16.5 6.8 0.0046 16.5 4.7 5.8 2 1 3 5 5 5 1 IncA protein Reo_sigmaC PF04582.7 EGO53383.1 - 3 6.9 22.5 0.5 9.5 0.3 4.8 2 2 3 5 5 5 0 Reovirus sigma C capsid protein Ceramidase PF05875.7 EGO53384.1 - 7.9e-102 339.8 13.6 9.1e-102 339.6 9.4 1.0 1 0 0 1 1 1 1 Ceramidase EamA PF00892.15 EGO53384.1 - 0.72 9.8 13.6 0.055 13.5 3.2 2.7 2 2 0 2 2 2 0 EamA-like transporter family DUF2157 PF09925.4 EGO53384.1 - 1.3 8.6 9.0 1.2 8.7 1.8 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) PAP2 PF01569.16 EGO53384.1 - 2.5 7.8 8.1 0.52 9.9 2.3 2.3 2 0 0 2 2 2 0 PAP2 superfamily DUF1049 PF06305.6 EGO53384.1 - 7.7 6.0 7.3 16 5.0 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Prefoldin_2 PF01920.15 EGO53385.1 - 7.2e-23 80.3 2.6 9.1e-23 80.0 1.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit CENP-Q PF13094.1 EGO53385.1 - 0.016 15.2 0.1 0.016 15.2 0.1 2.2 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Jnk-SapK_ap_N PF09744.4 EGO53385.1 - 0.027 14.4 0.8 0.027 14.4 0.6 1.8 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 TMF_TATA_bd PF12325.3 EGO53385.1 - 0.037 13.7 4.8 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Mst1_SARAH PF11629.3 EGO53385.1 - 0.074 12.8 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 RasGAP_C PF03836.10 EGO53385.1 - 0.11 12.1 0.1 0.11 12.1 0.1 1.9 2 1 0 2 2 2 0 RasGAP C-terminus DUF3683 PF12447.3 EGO53385.1 - 0.13 12.1 0.5 0.48 10.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3683) DUF972 PF06156.8 EGO53385.1 - 0.58 10.5 2.9 2.5 8.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) TBPIP PF07106.8 EGO53385.1 - 0.85 9.1 8.0 0.7 9.4 0.8 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2681 PF10883.3 EGO53385.1 - 1.3 9.2 5.9 4.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) ADIP PF11559.3 EGO53385.1 - 1.5 8.7 11.1 4.7 7.1 0.6 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 EGO53385.1 - 2.5 8.2 5.5 1.7 8.7 0.3 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.1 EGO53385.1 - 4.7 7.1 8.7 7 6.6 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) XhlA PF10779.4 EGO53385.1 - 8.3 6.4 8.0 0.65 9.9 1.3 2.0 2 1 0 2 2 2 0 Haemolysin XhlA Mnd1 PF03962.10 EGO53385.1 - 9.2 5.8 8.1 59 3.2 5.7 1.9 1 1 0 1 1 1 0 Mnd1 family Mito_carr PF00153.22 EGO53388.1 - 6.2e-54 179.6 1.6 9.8e-19 66.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Dor1 PF04124.7 EGO53389.1 - 1.9e-84 283.0 1.9 1.1e-78 264.1 0.2 3.0 2 1 1 3 3 3 3 Dor1-like family Cellulase-like PF12876.2 EGO53389.1 - 0.072 13.5 0.0 0.41 11.1 0.0 2.3 2 0 0 2 2 2 0 Sugar-binding cellulase-like TRAM_LAG1_CLN8 PF03798.11 EGO53391.1 - 2.4e-50 170.8 16.0 2.4e-50 170.8 11.1 1.6 2 0 0 2 2 2 1 TLC domain DUF4234 PF14018.1 EGO53391.1 - 0.44 10.3 5.8 0.42 10.3 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) SHD1 PF03983.7 EGO53392.1 - 9.7e-39 130.8 0.1 1.8e-38 130.0 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 EGO53392.1 - 3.3e-37 125.6 7.5 3.2e-13 48.8 0.2 4.5 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.1 EGO53392.1 - 2.2e-33 113.5 7.5 9.6e-13 47.5 0.1 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EGO53392.1 - 4e-25 87.0 0.2 9e-09 34.6 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 EGO53392.1 - 4.4e-06 26.7 2.6 0.23 11.7 0.8 3.5 3 0 0 3 3 3 3 Bacterial SH3 domain DUF1720 PF08226.6 EGO53392.1 - 3.7e-05 23.7 104.9 0.00025 21.0 45.5 5.4 2 1 3 5 5 5 3 Domain of unknown function (DUF1720) A_deaminase PF00962.17 EGO53393.1 - 2.9e-109 365.0 0.1 3.8e-109 364.5 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.6 EGO53394.1 - 9.1e-111 369.5 4.6 1.1e-110 369.3 3.2 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EGO53394.1 - 3.3e-06 26.3 0.3 3.3e-06 26.3 0.2 1.9 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 EGO53394.1 - 0.0019 17.8 4.2 0.0019 17.8 2.9 2.5 1 1 2 3 3 3 1 Triose-phosphate Transporter family Cytochrom_B561 PF03188.11 EGO53394.1 - 0.011 15.5 2.6 0.019 14.7 0.2 2.7 3 0 0 3 3 3 0 Eukaryotic cytochrome b561 EmrE PF13536.1 EGO53394.1 - 0.026 14.7 19.7 0.19 11.9 4.1 3.3 2 1 1 3 3 3 0 Multidrug resistance efflux transporter EamA PF00892.15 EGO53394.1 - 2.3 8.3 31.1 1.6 8.8 5.9 3.7 2 2 1 3 3 3 0 EamA-like transporter family Sybindin PF04099.7 EGO53396.1 - 4.7e-56 188.4 0.0 5.9e-56 188.1 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EGO53396.1 - 3.5e-08 33.3 0.1 6.2e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region VWA_2 PF13519.1 EGO53397.1 - 5.3e-14 52.6 0.0 7.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EGO53397.1 - 3.1e-08 33.4 0.0 4.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 EGO53397.1 - 1.9e-05 24.4 0.3 2.7e-05 23.9 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EGO53397.1 - 0.0012 18.2 5.7 0.0015 17.9 1.1 2.9 2 0 0 2 2 2 1 Ubiquitin interaction motif DHBP_synthase PF00926.14 EGO53397.1 - 0.045 12.9 0.1 12 5.0 0.0 2.7 2 1 1 3 3 3 0 3,4-dihydroxy-2-butanone 4-phosphate synthase DUF243 PF03103.12 EGO53397.1 - 0.2 11.8 0.1 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF243) DNA_pol3_a_NII PF11490.3 EGO53397.1 - 0.28 10.8 3.5 0.57 9.8 1.5 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II SPT2 PF08243.6 EGO53397.1 - 4 7.7 11.9 1.6 9.0 5.2 2.2 2 0 0 2 2 2 0 SPT2 chromatin protein Nbl1_Borealin_N PF10444.4 EGO53398.1 - 3.1e-23 80.9 3.0 6.3e-23 79.9 2.1 1.6 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Herpes_BLRF2 PF05812.7 EGO53398.1 - 5.9 6.7 11.6 0.056 13.2 1.5 2.4 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein SUI1 PF01253.17 EGO53399.1 - 6.6e-22 77.1 0.3 1.6e-21 75.8 0.2 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 EGO53399.1 - 0.00038 20.3 0.6 0.00069 19.4 0.4 1.4 1 0 0 1 1 1 1 Transposon-encoded protein TnpV Pox_RNA_Pol_19 PF05320.7 EGO53399.1 - 0.094 12.4 0.9 0.16 11.6 0.6 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Methyltransf_11 PF08241.7 EGO53401.1 - 7.4e-12 45.6 0.0 1.8e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO53401.1 - 0.00094 18.9 0.0 0.0023 17.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO53401.1 - 0.028 14.9 0.0 0.083 13.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EGO53401.1 - 0.036 13.1 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EGO53401.1 - 0.14 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain zf-C2H2_4 PF13894.1 EGO53404.1 - 8.5e-05 22.6 27.4 0.1 12.9 0.0 6.8 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGO53404.1 - 0.025 14.5 0.2 0.39 10.6 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_clus PF00172.13 EGO53404.1 - 0.052 13.4 6.0 0.19 11.6 4.2 2.0 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_bind PF08675.6 EGO53406.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain Metallophos PF00149.23 EGO53407.1 - 7.5e-07 28.7 1.1 7.5e-07 28.7 0.8 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SID-1_RNA_chan PF13965.1 EGO53407.1 - 5.3 5.0 3.8 7.9 4.5 2.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Polysacc_deac_1 PF01522.16 EGO53408.1 - 1.2e-27 96.0 0.0 2.1e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.8 EGO53408.1 - 0.14 11.1 0.0 0.96 8.4 0.0 2.2 3 0 0 3 3 3 0 Divergent polysaccharide deacetylase QRPTase_C PF01729.14 EGO53409.1 - 6.5e-54 181.9 0.1 8e-54 181.6 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EGO53409.1 - 5.4e-23 80.6 0.0 1.6e-22 79.1 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain IGPS PF00218.16 EGO53409.1 - 0.029 13.4 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EGO53409.1 - 0.037 13.5 0.1 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Glyco_hydro_61 PF03443.9 EGO53412.1 - 1.8e-51 175.0 1.3 2.1e-51 174.8 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RCC1 PF00415.13 EGO53413.1 - 2.6e-34 117.1 9.0 3.4e-06 27.1 0.0 8.9 8 2 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGO53413.1 - 8.8e-34 114.3 19.3 4.2e-09 35.7 1.6 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat PAN_4 PF14295.1 EGO53415.1 - 0.0064 16.1 4.4 0.013 15.2 3.0 1.5 1 0 0 1 1 1 1 PAN domain SHP PF03579.8 EGO53415.1 - 0.014 14.6 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 Small hydrophobic protein Transket_pyr PF02779.19 EGO53416.1 - 4.7e-44 150.0 0.0 7e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGO53416.1 - 2.4e-34 117.9 0.0 6.6e-34 116.5 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Aminotran_5 PF00266.14 EGO53416.1 - 0.01 14.6 0.0 0.022 13.5 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-V Sterol_MT_C PF08498.5 EGO53418.1 - 1e-28 99.0 0.9 1.5e-28 98.5 0.6 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EGO53418.1 - 1.9e-21 76.3 0.0 5e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO53418.1 - 4e-17 62.1 0.0 6.4e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO53418.1 - 4.9e-13 49.1 0.0 8.5e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO53418.1 - 1.2e-12 48.0 0.0 2.5e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO53418.1 - 5.3e-11 42.8 0.0 1.4e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO53418.1 - 1.1e-09 37.7 0.0 1.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EGO53418.1 - 1.7e-09 38.2 0.0 5.3e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EGO53418.1 - 6.2e-09 35.3 0.1 9e-09 34.8 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EGO53418.1 - 1.1e-08 35.0 0.0 3.6e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO53418.1 - 0.00014 21.3 0.0 0.00031 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 EGO53418.1 - 0.0014 18.2 0.1 0.0029 17.1 0.1 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_29 PF03141.11 EGO53418.1 - 0.0015 16.9 0.0 0.0022 16.3 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.8 EGO53418.1 - 0.0015 17.7 0.1 0.018 14.1 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 EGO53418.1 - 0.0041 16.5 0.0 0.0088 15.4 0.0 1.6 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.15 EGO53418.1 - 0.0048 15.9 0.0 0.0078 15.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EGO53418.1 - 0.008 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RRM_1 PF00076.17 EGO53419.1 - 7.6e-10 38.2 0.0 1.6e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO53419.1 - 2.2e-09 37.0 0.0 4.3e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO53419.1 - 2e-07 30.8 0.0 3.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGO53419.1 - 0.0048 16.7 0.1 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 EGO53419.1 - 0.0073 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DnaJ PF00226.26 EGO53420.1 - 2.2e-19 68.9 0.8 2.2e-19 68.9 0.5 2.4 2 1 0 2 2 2 1 DnaJ domain TraH PF06122.6 EGO53420.1 - 0.14 10.9 4.3 0.23 10.2 3.0 1.3 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein DUF1682 PF07946.9 EGO53420.1 - 7.3 5.3 23.6 17 4.1 16.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) AMP-binding PF00501.23 EGO53421.1 - 3e-79 266.3 0.0 4.8e-79 265.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EGO53421.1 - 1.7e-68 230.2 0.0 2.7e-68 229.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EGO53421.1 - 2.8e-12 46.5 0.0 5.7e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EGO53421.1 - 5.8e-11 42.5 0.0 1.4e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EGO53421.1 - 3.8e-09 35.6 0.3 1.2e-08 34.0 0.2 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 EGO53421.1 - 3.8e-08 34.1 0.1 2e-07 31.8 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 EGO53421.1 - 0.00031 20.6 1.0 0.0016 18.3 0.7 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EGO53421.1 - 0.0084 15.0 0.0 0.017 14.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EGO53421.1 - 0.014 14.2 0.1 0.46 9.3 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGO53421.1 - 0.021 14.8 0.1 0.54 10.2 0.1 2.5 1 1 0 1 1 1 0 NADH(P)-binding Aminotran_5 PF00266.14 EGO53422.1 - 2.4e-17 62.7 0.0 1.1e-11 44.0 0.0 3.9 2 2 0 2 2 2 2 Aminotransferase class-V Melittin PF01372.12 EGO53422.1 - 0.029 13.7 0.1 0.056 12.8 0.1 1.5 1 0 0 1 1 1 0 Melittin Sod_Cu PF00080.15 EGO53424.1 - 4.7e-20 72.1 0.1 6.4e-20 71.7 0.1 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HET PF06985.6 EGO53426.1 - 1.1e-23 83.8 0.0 2.8e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UbiA PF01040.13 EGO53427.1 - 2.9e-08 33.2 2.8 2.9e-08 33.2 1.9 2.0 2 0 0 2 2 2 1 UbiA prenyltransferase family CPSF100_C PF13299.1 EGO53428.1 - 0.03 14.5 5.3 0.06 13.5 0.0 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF3886 PF13025.1 EGO53428.1 - 0.34 10.8 31.8 0.077 12.9 5.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) RNA_pol_3_Rpc31 PF11705.3 EGO53428.1 - 3.4 7.5 12.4 0.056 13.3 2.7 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 WD40 PF00400.27 EGO53429.1 - 6.6e-08 32.1 1.5 0.096 12.6 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF4602 PF15375.1 EGO53429.1 - 1.9 8.5 4.4 0.33 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) Indigoidine_A PF04227.7 EGO53431.1 - 1.8e-107 358.9 0.9 2.9e-107 358.2 0.6 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EGO53431.1 - 1.8e-25 89.7 0.1 2.4e-24 85.9 0.0 2.7 2 1 0 2 2 2 1 pfkB family carbohydrate kinase HTH_DeoR PF08220.7 EGO53431.1 - 0.032 13.7 0.0 0.13 11.7 0.0 2.1 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Arrestin_N PF00339.24 EGO53432.1 - 1.2e-13 51.0 0.0 6.3e-12 45.5 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EGO53432.1 - 0.00092 19.3 0.0 0.0055 16.8 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain F-box-like PF12937.2 EGO53433.1 - 0.00046 19.8 0.6 0.00095 18.8 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO53433.1 - 0.00082 18.9 1.0 0.0018 17.9 0.7 1.5 1 0 0 1 1 1 1 F-box domain Nucleoplasmin PF03066.10 EGO53433.1 - 0.034 13.6 0.6 0.055 12.9 0.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin Mucin PF01456.12 EGO53433.1 - 0.7 9.6 14.4 1.5 8.6 10.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein FAD_binding_3 PF01494.14 EGO53434.1 - 2.6e-74 250.4 0.0 3.2e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGO53434.1 - 1.2e-31 109.5 0.0 2.3e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 EGO53434.1 - 1.1e-05 25.7 0.1 0.0015 18.9 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO53434.1 - 3.4e-05 23.8 0.0 0.00021 21.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO53434.1 - 0.00012 20.7 0.1 0.00023 19.7 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EGO53434.1 - 0.00031 20.7 0.1 0.0007 19.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGO53434.1 - 0.0044 17.1 0.0 0.01 15.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO53434.1 - 0.0059 15.7 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EGO53434.1 - 0.011 14.7 0.0 0.28 10.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGO53434.1 - 0.022 13.7 0.1 0.035 13.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EGO53434.1 - 0.025 13.2 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 EGO53434.1 - 0.067 12.0 0.1 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EGO53434.1 - 0.14 10.9 0.2 0.25 10.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain XdhC_C PF13478.1 EGO53434.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.9 EGO53434.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Vps53_N PF04100.7 EGO53435.1 - 1.4e-101 340.0 0.1 2.6e-101 339.1 0.1 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 EGO53435.1 - 2.8e-06 26.4 4.0 6e-06 25.3 2.8 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec6 PF06046.8 EGO53435.1 - 3.4e-05 22.1 0.0 0.00022 19.4 0.0 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec6 Sec15 PF04091.7 EGO53435.1 - 0.0031 16.9 0.0 0.01 15.2 0.0 1.8 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF2451 PF10474.4 EGO53435.1 - 0.0072 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Spc7 PF08317.6 EGO53435.1 - 0.011 14.4 0.6 0.022 13.4 0.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Zw10 PF06248.8 EGO53435.1 - 0.017 13.3 5.0 0.0047 15.1 1.2 1.6 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 Baculo_PEP_C PF04513.7 EGO53435.1 - 0.027 14.2 0.3 0.11 12.3 0.2 2.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rbsn PF11464.3 EGO53435.1 - 0.032 13.8 0.3 0.097 12.2 0.2 1.9 1 0 0 1 1 1 0 Rabenosyn Rab binding domain AAA_13 PF13166.1 EGO53435.1 - 0.066 11.6 0.4 0.76 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF3510 PF12022.3 EGO53435.1 - 0.54 10.3 3.5 0.72 9.9 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3510) ADIP PF11559.3 EGO53435.1 - 0.67 9.8 6.5 0.62 9.9 0.8 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Glyco_hydro_18 PF00704.23 EGO53436.1 - 2e-64 218.2 0.0 2.5e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3115 PF11312.3 EGO53436.1 - 0.02 13.7 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) ubiquitin PF00240.18 EGO53438.1 - 2.8e-17 61.8 0.1 4.1e-17 61.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EGO53438.1 - 6e-09 35.4 0.2 3.4e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 EGO53438.1 - 1.7e-06 27.6 0.2 2.4e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EGO53438.1 - 0.0038 17.1 0.1 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGO53438.1 - 0.0089 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain NPR2 PF06218.6 EGO53439.1 - 8.6e-101 337.7 0.0 3e-59 200.8 0.0 2.2 2 0 0 2 2 2 2 Nitrogen permease regulator 2 DUF566 PF04484.7 EGO53439.1 - 2.9 7.3 5.4 4.1 6.8 3.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) tRNA-synt_1b PF00579.20 EGO53440.1 - 2.5e-90 302.5 0.2 1.9e-89 299.6 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) ERO1 PF04137.10 EGO53440.1 - 0.043 12.8 2.6 0.083 11.8 1.8 1.4 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) CybS PF05328.7 EGO53441.1 - 6.9e-51 171.3 0.0 8.7e-51 171.0 0.0 1.1 1 0 0 1 1 1 1 CybS DUF3419 PF11899.3 EGO53442.1 - 4.6e-151 502.8 0.0 7.1e-151 502.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EGO53442.1 - 1.2e-12 47.8 0.0 4.6e-11 42.6 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO53442.1 - 1.3e-08 35.3 0.0 5.5e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO53442.1 - 1.4e-08 34.4 0.0 4.3e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO53442.1 - 1.3e-06 28.7 0.0 6.9e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO53442.1 - 2.6e-06 27.4 0.0 0.00013 21.9 0.0 2.9 2 2 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO53442.1 - 2.2e-05 23.7 0.1 0.0014 17.7 0.0 2.6 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EGO53442.1 - 2.6e-05 24.6 0.0 0.0045 17.4 0.0 3.3 4 0 0 4 4 4 1 Methyltransferase domain PCMT PF01135.14 EGO53442.1 - 0.00065 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EGO53442.1 - 0.031 13.3 0.0 0.21 10.5 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_28 PF02636.12 EGO53442.1 - 0.14 11.5 0.0 1.4 8.3 0.0 2.2 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CBFB_NFYA PF02045.10 EGO53443.1 - 1.2e-30 105.8 4.5 2.4e-30 104.8 3.1 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 EGO53443.1 - 0.014 14.3 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein PPP4R2 PF09184.6 EGO53448.1 - 0.71 9.3 14.2 1.1 8.7 9.8 1.2 1 0 0 1 1 1 0 PPP4R2 FLO_LFY PF01698.11 EGO53448.1 - 3.4 6.4 8.1 4.9 5.9 5.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein TATR PF03430.8 EGO53448.1 - 9.4 4.7 7.0 12 4.3 4.9 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator VRR_NUC PF08774.6 EGO53449.1 - 7.4e-20 70.8 0.0 2.3e-19 69.2 0.0 1.9 1 0 0 1 1 1 1 VRR-NUC domain Dpy-30 PF05186.8 EGO53450.1 - 1.3e-13 50.1 0.0 1.3e-13 50.1 0.0 1.6 2 0 0 2 2 2 1 Dpy-30 motif Ribosomal_S13_N PF08069.7 EGO53451.1 - 2.6e-31 107.2 0.2 5.3e-31 106.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EGO53451.1 - 5.4e-23 80.5 0.0 9.5e-23 79.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EGO53451.1 - 0.015 15.0 0.1 0.037 13.7 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain RRM_1 PF00076.17 EGO53452.1 - 3.3e-30 103.5 0.0 5.2e-13 48.4 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO53452.1 - 2.3e-18 65.9 0.0 9.9e-08 31.8 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO53452.1 - 3.9e-14 52.2 0.0 1e-05 25.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 EGO53452.1 - 0.024 14.6 0.0 0.098 12.7 0.0 1.9 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) gpUL132 PF11359.3 EGO53452.1 - 6.2 6.0 7.9 13 5.0 5.5 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 OGG_N PF07934.7 EGO53453.1 - 1.9e-14 53.6 0.2 6.1e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EGO53453.1 - 3.2e-13 49.8 0.0 5.6e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EGO53453.1 - 0.029 14.0 0.0 0.079 12.6 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif HECT_2 PF09814.4 EGO53454.1 - 8.1e-87 291.2 0.0 9.4e-87 290.9 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding GFA PF04828.9 EGO53454.1 - 0.096 12.6 0.3 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme SF3b1 PF08920.5 EGO53455.1 - 1.4e-36 125.7 3.5 1.5e-36 125.5 0.1 2.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EGO53455.1 - 1.4e-15 57.2 3.6 0.01 16.1 0.0 7.4 6 3 2 8 8 8 6 HEAT repeats HEAT_EZ PF13513.1 EGO53455.1 - 6e-12 45.6 0.7 0.34 11.4 0.0 7.8 7 1 1 8 8 8 2 HEAT-like repeat HEAT PF02985.17 EGO53455.1 - 4.6e-11 41.8 9.6 0.95 9.7 0.0 9.5 10 0 0 10 10 10 3 HEAT repeat Vac14_Fab1_bd PF12755.2 EGO53455.1 - 3.2e-06 27.4 0.3 0.49 10.8 0.0 5.4 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EGO53455.1 - 6.6e-05 21.4 0.4 0.02 13.2 0.0 3.1 2 2 0 3 3 3 2 Adaptin N terminal region UPF0236 PF06782.6 EGO53455.1 - 0.001 17.6 0.1 0.0018 16.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0236) NUC173 PF08161.7 EGO53455.1 - 0.0077 15.6 0.4 4.9 6.4 0.0 3.8 4 0 0 4 4 4 1 NUC173 domain CLASP_N PF12348.3 EGO53455.1 - 0.0081 15.5 0.2 1.3 8.3 0.0 3.6 4 0 0 4 4 4 1 CLASP N terminal RR_TM4-6 PF06459.7 EGO53455.1 - 2.8 7.7 5.2 4.9 6.9 3.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-H2C2_2 PF13465.1 EGO53456.1 - 4.6e-11 42.4 13.9 1.8e-06 27.9 0.3 3.3 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EGO53456.1 - 1.7e-09 37.4 12.4 1.9e-05 24.6 3.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO53456.1 - 2.6e-07 30.4 9.3 0.0002 21.4 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGO53456.1 - 2e-06 27.5 4.6 0.004 17.0 1.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EGO53456.1 - 4.9e-06 26.5 1.6 1.6e-05 24.9 0.9 2.2 1 1 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGO53456.1 - 5.5e-05 23.1 5.9 0.00013 22.0 1.5 2.7 2 1 1 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGO53456.1 - 0.077 13.1 3.8 0.092 12.8 1.7 1.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 EGO53456.1 - 0.23 11.1 2.3 6.1 6.6 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PHB_acc PF05233.8 EGO53456.1 - 0.56 9.9 4.2 1.2 8.9 0.8 2.4 2 0 0 2 2 2 0 PHB accumulation regulatory domain zf-BED PF02892.10 EGO53456.1 - 0.8 9.5 5.5 7.4 6.4 3.8 2.2 1 1 0 1 1 1 0 BED zinc finger Rax2 PF12768.2 EGO53459.1 - 2.7e-98 328.6 5.6 2.6e-85 286.0 0.0 4.7 4 0 0 4 4 4 4 Cortical protein marker for cell polarity Kelch_6 PF13964.1 EGO53459.1 - 7.8e-05 22.6 9.0 0.24 11.6 0.0 6.3 6 1 1 7 7 7 2 Kelch motif Kelch_4 PF13418.1 EGO53459.1 - 0.0094 15.7 6.4 0.029 14.1 0.1 4.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 EGO53459.1 - 0.014 14.9 0.3 0.072 12.6 0.0 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.10 EGO53459.1 - 0.019 14.7 3.5 0.48 10.2 0.0 4.1 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 EGO53459.1 - 0.093 12.9 19.3 0.15 12.2 0.4 5.6 6 0 0 6 6 6 0 Galactose oxidase, central domain SNase PF00565.12 EGO53461.1 - 1.7e-22 79.6 0.4 3.4e-22 78.7 0.0 1.6 2 0 0 2 2 2 1 Staphylococcal nuclease homologue Med9 PF07544.8 EGO53463.1 - 0.088 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 HAD PF12710.2 EGO53464.1 - 9.4e-17 61.7 0.0 1.4e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO53464.1 - 3e-05 24.5 0.0 5.9e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGO53464.1 - 5.6e-05 23.4 0.0 0.008 16.4 0.0 2.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EGO53464.1 - 0.053 12.6 0.0 0.53 9.4 0.0 2.0 2 0 0 2 2 2 0 Putative Phosphatase TFIIF_beta PF02270.10 EGO53465.1 - 6.8e-78 262.2 0.4 8.3e-78 261.9 0.3 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit zf-CCCH PF00642.19 EGO53466.1 - 0.0001 21.8 15.2 0.28 10.9 0.0 5.2 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pyr_redox_3 PF13738.1 EGO53467.1 - 7.9e-16 58.7 0.2 7e-09 36.0 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO53467.1 - 2.4e-07 29.9 0.0 0.0019 17.2 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EGO53467.1 - 2.9e-07 29.0 0.2 0.00042 18.6 0.0 2.9 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like DAO PF01266.19 EGO53467.1 - 8e-06 24.9 0.2 0.037 12.9 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO53467.1 - 1e-05 25.5 0.1 0.028 14.3 0.1 2.6 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO53467.1 - 0.00014 21.6 0.5 0.0087 15.8 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.17 EGO53467.1 - 0.00046 19.1 0.2 0.24 10.1 0.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EGO53467.1 - 0.00091 19.2 0.1 0.0031 17.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGO53467.1 - 0.0015 17.7 0.4 0.0095 15.0 0.0 2.2 3 0 0 3 3 3 1 Thi4 family AlaDh_PNT_C PF01262.16 EGO53467.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EGO53467.1 - 0.093 11.1 0.6 0.24 9.8 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 EGO53467.1 - 0.094 11.5 0.1 0.16 10.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EGO53467.1 - 0.1 13.0 0.2 0.92 9.9 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 EGO53467.1 - 0.12 11.8 0.1 11 5.5 0.0 2.4 3 0 0 3 3 3 0 Malic enzyme, NAD binding domain P34-Arc PF04045.9 EGO53468.1 - 2.8e-100 334.5 0.4 3.5e-100 334.2 0.3 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc WD40 PF00400.27 EGO53469.1 - 2.9e-69 226.6 19.6 3.8e-09 36.0 0.1 13.1 13 0 0 13 13 13 10 WD domain, G-beta repeat Utp12 PF04003.7 EGO53469.1 - 1.5e-21 76.3 0.4 2.8e-21 75.4 0.3 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EGO53469.1 - 2.7e-05 22.5 0.6 0.0057 14.8 0.1 4.3 3 2 1 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGO53469.1 - 0.00082 18.2 6.3 0.54 8.9 0.7 5.4 2 1 1 4 4 4 1 Nup133 N terminal like TFIIF_alpha PF05793.7 EGO53471.1 - 1.4 7.1 31.8 2.2 6.5 22.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sel1 PF08238.7 EGO53472.1 - 2.3e-21 75.7 7.4 6.3e-07 29.8 0.0 4.3 4 0 0 4 4 4 3 Sel1 repeat Steroid_dh PF02544.11 EGO53473.1 - 0.54 10.0 9.2 1.3 8.7 0.0 2.6 3 0 0 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase Innexin PF00876.13 EGO53473.1 - 2.8 6.9 6.5 4 6.4 4.5 1.1 1 0 0 1 1 1 0 Innexin bZIP_Maf PF03131.12 EGO53474.1 - 2.2e-08 34.3 13.5 7.9e-08 32.4 9.3 2.0 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EGO53474.1 - 8.9e-07 28.7 20.7 1e-06 28.5 9.1 3.0 1 1 2 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 EGO53474.1 - 0.001 18.8 15.4 0.001 18.8 10.7 3.3 1 1 1 3 3 3 1 Basic region leucine zipper tRNA-synt_1e PF01406.14 EGO53474.1 - 0.084 11.9 1.2 0.13 11.3 0.8 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Endotoxin_N PF03945.9 EGO53474.1 - 0.11 11.8 4.7 0.26 10.6 3.2 1.6 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain DUF342 PF03961.8 EGO53474.1 - 0.65 8.3 12.4 1 7.6 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CCDC155 PF14662.1 EGO53474.1 - 0.75 9.3 21.9 1.9 8.0 15.2 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 DUF724 PF05266.9 EGO53474.1 - 1 8.9 14.1 2.3 7.7 9.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) APG6 PF04111.7 EGO53474.1 - 6.2 5.7 18.8 10 5.0 13.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Prominin PF05478.6 EGO53474.1 - 9.8 3.5 7.9 15 2.9 5.5 1.2 1 0 0 1 1 1 0 Prominin CBF PF03914.12 EGO53476.1 - 1.1e-44 151.7 0.3 3e-44 150.3 0.0 1.9 2 0 0 2 2 2 1 CBF/Mak21 family LemA PF04011.7 EGO53476.1 - 0.031 13.3 1.0 0.074 12.1 0.3 1.8 2 0 0 2 2 2 0 LemA family HEAT_2 PF13646.1 EGO53476.1 - 0.06 13.6 0.2 0.63 10.3 0.0 2.7 1 1 1 2 2 2 0 HEAT repeats Utp12 PF04003.7 EGO53476.1 - 0.098 12.5 3.7 1.9 8.4 0.1 3.3 3 0 0 3 3 3 0 Dip2/Utp12 Family Syntaxin-18_N PF10496.4 EGO53476.1 - 0.23 11.3 3.6 0.44 10.4 0.9 2.7 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF4111 PF13427.1 EGO53476.1 - 0.25 11.1 2.9 14 5.6 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) IncA PF04156.9 EGO53476.1 - 0.84 9.1 5.6 0.16 11.5 0.9 2.0 2 0 0 2 2 2 0 IncA protein Mt_ATP-synt_B PF05405.9 EGO53477.1 - 5e-55 185.4 5.2 6e-55 185.1 3.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Orthopox_A5L PF06193.6 EGO53477.1 - 0.027 14.3 0.3 0.056 13.3 0.0 1.7 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like DUF1539 PF07560.6 EGO53477.1 - 0.074 12.9 0.5 0.13 12.0 0.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) AAA_23 PF13476.1 EGO53477.1 - 0.097 12.9 1.1 0.11 12.7 0.8 1.1 1 0 0 1 1 1 0 AAA domain Dak2 PF02734.12 EGO53477.1 - 0.24 11.0 3.2 0.39 10.3 1.5 1.8 1 1 1 2 2 2 0 DAK2 domain Methyltransf_26 PF13659.1 EGO53479.1 - 5.6e-18 65.0 0.0 8.6e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO53479.1 - 0.0003 20.1 0.0 0.00046 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Pkr1 PF08636.5 EGO53480.1 - 3.4e-35 119.9 6.7 4.5e-35 119.5 4.6 1.2 1 0 0 1 1 1 1 ER protein Pkr1 ATP_synt_I PF03899.10 EGO53480.1 - 0.02 15.0 0.3 0.031 14.4 0.2 1.2 1 0 0 1 1 1 0 ATP synthase I chain FHIPEP PF00771.15 EGO53480.1 - 0.045 12.0 0.1 0.054 11.8 0.1 1.0 1 0 0 1 1 1 0 FHIPEP family OAD_gamma PF04277.8 EGO53480.1 - 0.13 12.6 0.7 0.29 11.5 0.5 1.8 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Cullin PF00888.17 EGO53483.1 - 9.3e-63 212.6 0.0 1.6e-62 211.9 0.0 1.2 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 EGO53483.1 - 2.4e-20 72.5 0.1 5.7e-20 71.3 0.1 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Flg_hook PF02120.11 EGO53483.1 - 0.032 13.9 0.5 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK APH PF01636.18 EGO53484.1 - 7.9e-46 156.7 0.2 2.7e-45 154.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGO53484.1 - 1.8e-06 27.3 0.0 2.6e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 EGO53484.1 - 0.0018 17.6 0.0 0.46 9.8 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 EGO53484.1 - 0.0019 17.8 0.0 0.0035 16.9 0.0 1.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EGO53484.1 - 0.0088 15.0 0.0 1.8 7.4 0.0 2.3 2 1 0 2 2 2 2 Fructosamine kinase DUF1679 PF07914.6 EGO53484.1 - 0.11 11.1 0.0 0.21 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Rad17 PF03215.10 EGO53488.1 - 2.9e-55 187.9 0.0 4.7e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EGO53488.1 - 0.00024 21.2 0.0 0.00059 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO53488.1 - 0.0011 18.6 0.0 0.0034 17.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGO53488.1 - 0.0017 17.9 0.1 0.0057 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGO53488.1 - 0.013 15.6 0.0 0.045 13.9 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF853 PF05872.7 EGO53488.1 - 0.016 13.5 0.0 0.033 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_16 PF13191.1 EGO53488.1 - 0.03 14.3 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 EGO53488.1 - 0.044 12.6 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 EGO53488.1 - 0.059 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 EGO53488.1 - 0.079 13.7 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGO53488.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGO53488.1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4243 PF14027.1 EGO53489.1 - 4.4e-79 266.3 0.3 5.4e-79 266.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Ribul_P_3_epim PF00834.14 EGO53490.1 - 1.6e-64 216.6 0.0 8.1e-64 214.4 0.0 1.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.9 EGO53490.1 - 0.021 13.8 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.19 EGO53490.1 - 0.026 13.9 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.14 EGO53490.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Glyco_hydro_31 PF01055.21 EGO53490.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 Ofd1_CTDD PF10637.4 EGO53491.1 - 8.5e-104 346.3 0.1 1.5e-95 319.3 0.2 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EGO53491.1 - 5.5e-15 55.7 0.0 1.6e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EGO53491.1 - 0.014 14.9 0.0 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Cys_Met_Meta_PP PF01053.15 EGO53493.1 - 2.4e-58 197.2 0.0 5.7e-58 196.0 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ank_4 PF13637.1 EGO53494.1 - 0.043 14.3 0.0 0.18 12.3 0.0 2.1 2 1 0 2 2 2 0 Ankyrin repeats (many copies) APC_15aa PF05972.6 EGO53494.1 - 0.16 12.0 0.3 0.33 11.0 0.2 1.5 1 0 0 1 1 1 0 APC 15 residue motif SIR2 PF02146.12 EGO53495.1 - 3.3e-56 189.8 0.0 4.7e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EGO53495.1 - 0.00037 20.2 0.1 0.02 14.6 0.0 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain zf-LYAR PF08790.6 EGO53495.1 - 0.061 13.0 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger ArabFuran-catal PF09206.6 EGO53496.1 - 0.18 10.6 1.8 2.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Alpha-L-arabinofuranosidase B, catalytic Cu-oxidase_3 PF07732.10 EGO53498.1 - 2.8e-44 149.6 4.5 2.4e-41 140.1 0.1 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGO53498.1 - 6.9e-35 119.5 7.0 1.5e-34 118.4 0.4 3.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EGO53498.1 - 2.6e-34 118.4 0.0 6.4e-34 117.1 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase Romo1 PF10247.4 EGO53499.1 - 1e-29 102.4 12.0 1.4e-29 102.0 8.3 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 FHA PF00498.21 EGO53500.1 - 1.5e-17 63.4 0.0 4.2e-17 62.0 0.0 1.9 1 0 0 1 1 1 1 FHA domain nsp8 PF08717.5 EGO53500.1 - 0.032 13.8 0.5 0.078 12.5 0.3 1.6 1 0 0 1 1 1 0 nsp8 replicase Cutinase PF01083.17 EGO53506.1 - 2.4e-06 27.4 0.0 3.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Cutinase DUF676 PF05057.9 EGO53506.1 - 5.7e-05 22.5 0.0 6.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EGO53506.1 - 0.00018 21.1 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EGO53506.1 - 0.00094 19.1 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EGO53506.1 - 0.0099 15.4 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.2 EGO53506.1 - 0.014 15.1 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 EGO53506.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) tRNA-synt_2c PF01411.14 EGO53507.1 - 3.5e-08 32.2 0.0 4.5e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EGO53507.1 - 3.3e-06 26.8 0.6 6.2e-06 25.9 0.4 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Abhydrolase_1 PF00561.15 EGO53508.1 - 6.2e-17 61.9 0.0 2e-16 60.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGO53508.1 - 5.6e-11 42.7 1.5 3.2e-10 40.2 1.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGO53508.1 - 0.00012 21.6 0.0 0.00028 20.3 0.0 1.6 1 0 0 1 1 1 1 Putative esterase PAP_assoc PF03828.14 EGO53510.1 - 1.3e-17 63.4 0.1 3.7e-17 62.0 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EGO53510.1 - 2.1e-06 27.9 0.6 3.4e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyltransferase domain DUF914 PF06027.7 EGO53515.1 - 1.5e-99 333.0 19.6 2e-99 332.6 13.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EGO53515.1 - 2.8e-06 27.3 9.4 2.8e-06 27.3 6.5 2.5 2 1 0 2 2 2 1 EamA-like transporter family CoatB PF10389.4 EGO53515.1 - 0.023 14.5 0.4 0.12 12.2 0.3 2.2 1 0 0 1 1 1 0 Bacteriophage coat protein B Ninjurin PF04923.7 EGO53515.1 - 0.037 13.7 0.3 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Ninjurin TPT PF03151.11 EGO53515.1 - 6.2 6.4 23.8 0.19 11.4 4.0 2.4 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF4576 PF15144.1 EGO53516.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) DNA_pol_phi PF04931.8 EGO53516.1 - 0.69 7.6 21.9 12 3.5 16.5 1.8 2 0 0 2 2 2 0 DNA polymerase phi Nop14 PF04147.7 EGO53516.1 - 2.3 6.0 12.8 2.9 5.6 8.9 1.3 1 0 0 1 1 1 0 Nop14-like family NUDIX PF00293.23 EGO53520.1 - 1.6e-15 56.8 0.0 2.3e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 EGO53521.1 - 1.8e-06 27.6 0.0 2.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain GST_N_3 PF13417.1 EGO53522.1 - 3.2e-24 84.9 0.0 8.2e-24 83.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO53522.1 - 2.4e-18 65.8 0.0 6.9e-18 64.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO53522.1 - 1.4e-09 37.7 0.0 3.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGO53522.1 - 2.3e-05 24.4 0.0 8.2e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO53522.1 - 0.00063 19.6 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO53522.1 - 0.004 17.5 0.0 0.015 15.7 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain zf-C3H1 PF10650.4 EGO53523.1 - 1e-09 37.6 1.0 1.7e-09 36.9 0.7 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain Ribosomal_L18_c PF14204.1 EGO53523.1 - 0.043 14.3 0.1 0.043 14.3 0.1 2.2 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region MerR-DNA-bind PF09278.6 EGO53523.1 - 9.2 6.7 10.7 1 9.8 0.3 3.2 3 0 0 3 3 3 0 MerR, DNA binding Amino_oxidase PF01593.19 EGO53524.1 - 5.9e-17 61.8 0.1 6.6e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGO53524.1 - 9.8e-14 51.1 0.1 2e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO53524.1 - 3.3e-13 49.2 5.0 2.9e-12 46.1 1.9 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGO53524.1 - 4.8e-06 25.3 0.4 0.0017 16.9 0.8 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EGO53524.1 - 5.4e-06 26.4 0.0 1.8e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO53524.1 - 6.1e-06 25.5 0.0 0.00022 20.4 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO53524.1 - 2.3e-05 23.4 3.9 7.9e-05 21.6 2.2 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EGO53524.1 - 3.1e-05 24.1 0.1 0.00033 20.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO53524.1 - 0.00039 19.5 0.5 0.00083 18.5 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EGO53524.1 - 0.0017 17.4 0.4 0.003 16.6 0.3 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EGO53524.1 - 0.0026 18.1 8.6 0.016 15.6 1.1 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EGO53524.1 - 0.0032 16.9 0.8 0.0065 15.9 0.5 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 EGO53524.1 - 0.013 15.2 0.9 0.032 14.0 0.2 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EGO53524.1 - 0.098 11.5 1.7 0.21 10.4 0.6 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 EGO53524.1 - 0.12 11.2 3.3 0.11 11.3 1.3 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EGO53524.1 - 0.23 11.1 1.2 0.47 10.0 0.9 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EGO53524.1 - 0.87 8.1 4.4 1.7 7.2 0.8 2.1 2 0 0 2 2 2 0 Tryptophan halogenase RhoGAP PF00620.22 EGO53525.1 - 4.6e-48 162.6 0.0 1.3e-47 161.2 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EGO53525.1 - 1.1e-16 60.7 0.4 2.5e-16 59.6 0.3 1.6 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Sugarporin_N PF11471.3 EGO53525.1 - 0.064 12.9 0.1 0.2 11.3 0.1 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension OmpH PF03938.9 EGO53525.1 - 0.075 12.9 6.6 0.16 11.9 4.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.1 EGO53525.1 - 0.23 10.3 5.6 0.38 9.6 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Striatin PF08232.7 EGO53525.1 - 1.3 9.3 4.7 0.34 11.2 0.6 2.0 2 0 0 2 2 2 0 Striatin family TPR_MLP1_2 PF07926.7 EGO53525.1 - 2.2 8.0 9.4 0.37 10.5 2.2 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Semialdhyde_dhC PF02774.13 EGO53526.1 - 3.4e-40 137.8 0.0 4.8e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EGO53526.1 - 2.8e-30 105.1 0.0 8e-30 103.6 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EGO53526.1 - 0.0016 18.3 0.0 0.0034 17.2 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EGO53526.1 - 0.011 16.2 0.1 0.029 14.8 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DXP_reductoisom PF02670.11 EGO53526.1 - 0.077 13.5 0.0 0.3 11.6 0.0 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase adh_short PF00106.20 EGO53527.1 - 2.3e-20 73.2 0.2 4.9e-12 46.0 0.0 2.4 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 EGO53527.1 - 1.1e-09 38.2 0.0 1.6e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EGO53527.1 - 1.8e-06 27.9 0.0 7.7e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase VanY PF02557.12 EGO53527.1 - 0.052 13.4 0.0 5.8 6.7 0.0 2.3 1 1 1 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Epimerase PF01370.16 EGO53527.1 - 0.06 12.7 0.4 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGO53527.1 - 0.074 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RRM_1 PF00076.17 EGO53528.1 - 5.2e-18 64.4 0.0 1.6e-13 50.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO53528.1 - 6.4e-12 45.2 0.0 1.4e-06 28.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO53528.1 - 0.065 13.0 0.0 8.1 6.3 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 EGO53529.1 - 0.11 12.4 3.3 0.2 11.5 2.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex14_N PF04695.8 EGO53529.1 - 3.9 7.5 9.9 1.2 9.1 3.8 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.27 EGO53531.1 - 2e-16 59.1 9.1 4.8e-05 23.0 0.1 5.9 5 1 0 5 5 5 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EGO53531.1 - 0.052 13.0 0.0 0.41 10.0 0.0 2.2 1 1 0 1 1 1 0 PQQ-like domain Arb2 PF09757.4 EGO53534.1 - 6.7e-22 77.7 0.0 1.2e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Arb2 domain CCDC50_N PF15295.1 EGO53534.1 - 0.017 15.0 3.9 0.03 14.2 2.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Radical_SAM PF04055.16 EGO53535.1 - 3e-16 60.0 0.0 4.6e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Synaptobrevin PF00957.16 EGO53536.1 - 1e-32 111.6 1.9 1.1e-32 111.4 1.3 1.0 1 0 0 1 1 1 1 Synaptobrevin TMEM117 PF15113.1 EGO53536.1 - 0.021 13.4 0.4 0.023 13.3 0.3 1.0 1 0 0 1 1 1 0 TMEM117 protein family DUF1035 PF06281.7 EGO53536.1 - 0.11 12.2 3.1 0.17 11.6 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) DUF619 PF04768.8 EGO53537.1 - 1.3e-50 171.1 0.1 2.3e-50 170.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EGO53537.1 - 5e-32 110.7 0.0 1.7e-31 109.0 0.0 2.0 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EGO53537.1 - 1.5e-30 106.5 0.1 3e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 EGO53537.1 - 0.0014 18.5 0.0 0.0037 17.1 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Methyltransf_3 PF01596.12 EGO53537.1 - 0.11 11.4 0.0 1.4 7.8 0.0 2.4 2 0 0 2 2 2 0 O-methyltransferase Peptidase_A22B PF04258.8 EGO53539.1 - 4.6e-55 187.1 0.3 1.8e-54 185.2 0.2 1.8 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EGO53539.1 - 0.028 13.5 9.2 0.034 13.2 4.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1119) Hum_adeno_E3A PF05393.6 EGO53539.1 - 0.094 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Ribosomal_60s PF00428.14 EGO53539.1 - 2.7 8.4 13.3 10 6.6 0.9 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Med31 PF05669.7 EGO53540.1 - 9.2e-36 121.6 0.0 1e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 SOH1 TFIIS_C PF01096.13 EGO53541.1 - 2.8e-20 71.6 3.0 2.8e-20 71.6 2.1 2.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EGO53541.1 - 2.3e-11 43.1 0.2 2.3e-11 43.1 0.1 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 EGO53541.1 - 0.098 12.9 4.4 8.9 6.7 3.1 2.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EGO53541.1 - 0.14 12.0 4.9 3.1 7.6 0.1 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Elf1 PF05129.8 EGO53541.1 - 0.29 10.8 3.3 6.1 6.6 0.0 2.7 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like C1_4 PF07975.7 EGO53541.1 - 0.31 11.0 2.8 7.5 6.6 0.1 2.7 2 1 0 2 2 2 0 TFIIH C1-like domain C1_3 PF07649.7 EGO53541.1 - 0.57 10.2 0.2 0.57 10.2 0.1 2.9 3 1 0 3 3 3 0 C1-like domain Ank_2 PF12796.2 EGO53542.1 - 8.4e-11 42.0 0.0 1.8e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGO53542.1 - 2.1e-10 39.8 0.0 0.007 16.1 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGO53542.1 - 2.2e-10 40.7 1.0 3.2e-05 24.2 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO53542.1 - 4.6e-08 32.5 0.0 0.098 12.9 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EGO53542.1 - 4.8e-08 33.0 0.2 0.065 13.5 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Thaumatin PF00314.12 EGO53543.1 - 2.4e-74 249.3 0.8 3e-74 249.0 0.5 1.1 1 0 0 1 1 1 1 Thaumatin family HSP70 PF00012.15 EGO53547.1 - 3.2e-11 41.8 0.3 1.3e-09 36.5 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EGO53547.1 - 0.0041 16.7 0.1 0.009 15.6 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 EGO53547.1 - 0.028 13.0 0.1 0.15 10.6 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Met_asp_mut_E PF06368.6 EGO53548.1 - 0.099 10.8 0.0 0.12 10.5 0.0 1.0 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Hexokinase_2 PF03727.11 EGO53550.1 - 2.6e-63 213.4 0.0 4.2e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EGO53550.1 - 5.9e-63 211.9 0.1 9.8e-63 211.2 0.1 1.4 1 0 0 1 1 1 1 Hexokinase adh_short PF00106.20 EGO53550.1 - 0.046 13.6 0.1 0.096 12.5 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Acetyltransf_1 PF00583.19 EGO53551.1 - 0.00019 21.4 0.0 0.00049 20.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGO53551.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sgf11 PF08209.6 EGO53552.1 - 1.7 8.0 7.4 0.2 10.9 2.2 1.7 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Pro_isomerase PF00160.16 EGO53553.1 - 1.4e-51 174.7 0.1 1.7e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Oxysterol_BP PF01237.13 EGO53554.1 - 1.8e-128 428.0 0.9 3e-128 427.2 0.0 1.8 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 EGO53554.1 - 1.1e-18 67.3 0.1 5e-12 45.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGO53554.1 - 4.1e-16 57.8 0.1 2.8e-06 26.8 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EGO53554.1 - 7.1e-16 57.8 1.1 1.1e-08 35.0 0.1 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGO53554.1 - 1.4e-14 54.1 0.1 8.5e-08 32.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO53554.1 - 7.8e-14 50.4 0.1 6.5e-06 25.8 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.24 EGO53554.1 - 2.9e-12 46.7 0.3 6e-12 45.6 0.2 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EGO53554.1 - 1.2e-07 31.6 0.7 3.7e-07 30.1 0.5 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain 4HBT_3 PF13622.1 EGO53555.1 - 3e-48 164.7 0.4 4.4e-48 164.2 0.3 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EGO53555.1 - 1e-21 76.9 0.0 2.6e-11 43.2 0.0 4.0 3 1 0 3 3 3 3 Acyl-CoA thioesterase 4HBT PF03061.17 EGO53555.1 - 0.00012 22.1 0.0 0.19 11.8 0.0 2.6 2 0 0 2 2 2 2 Thioesterase superfamily DUF2668 PF10873.3 EGO53555.1 - 0.014 15.5 0.6 0.023 14.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) ACPS PF01648.15 EGO53557.1 - 2e-06 27.5 0.0 5.6e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily FAD_binding_7 PF03441.9 EGO53558.1 - 8.9e-59 198.9 0.1 1.3e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EGO53558.1 - 1e-21 77.3 0.0 1.6e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase ORF11CD3 PF10549.4 EGO53558.1 - 0.17 11.6 0.3 13 5.5 0.1 2.5 2 0 0 2 2 2 0 ORF11CD3 domain 4HBT PF03061.17 EGO53560.1 - 0.00013 22.0 0.1 0.00032 20.7 0.0 1.7 2 0 0 2 2 2 1 Thioesterase superfamily PLRV_ORF5 PF01690.12 EGO53560.1 - 0.17 10.9 1.3 0.26 10.3 0.9 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SQS_PSY PF00494.14 EGO53562.1 - 4.6e-72 242.5 0.1 7.9e-72 241.7 0.1 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase SUR7 PF06687.7 EGO53563.1 - 1.5e-36 125.9 4.9 2e-36 125.5 3.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EGO53563.1 - 2.8e-05 23.8 16.1 0.00019 21.1 10.8 2.0 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction MNSV_P7B PF06692.6 EGO53563.1 - 0.044 13.5 1.2 8.6 6.2 0.0 2.8 3 0 0 3 3 3 0 Melon necrotic spot virus P7B protein Pkinase PF00069.20 EGO53564.1 - 1.2e-50 172.0 0.0 1.7e-47 161.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO53564.1 - 1.4e-29 102.9 0.0 5.5e-28 97.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO53564.1 - 0.00031 19.8 0.0 0.00048 19.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGO53564.1 - 0.0025 16.7 0.1 0.0043 15.9 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EGO53564.1 - 0.057 13.1 0.1 0.17 11.6 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EGO53564.1 - 0.26 10.0 0.1 0.38 9.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Mem_trans PF03547.13 EGO53565.1 - 7e-51 172.7 0.0 1.6e-50 171.5 0.0 1.6 1 1 0 1 1 1 1 Membrane transport protein Pyridox_oxidase PF01243.15 EGO53566.1 - 5.4e-13 48.7 0.0 2.2e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 EGO53566.1 - 0.0011 18.7 0.0 0.039 13.7 0.0 2.2 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase CPSase_L_D2 PF02786.12 EGO53567.1 - 4.9e-74 248.1 0.0 7.6e-74 247.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EGO53567.1 - 1.3e-36 124.8 0.0 3.1e-36 123.6 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EGO53567.1 - 1.9e-33 114.8 0.1 7.6e-33 112.9 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EGO53567.1 - 8.5e-19 68.0 0.2 2.7e-18 66.3 0.0 1.9 3 0 0 3 3 3 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGO53567.1 - 6.3e-17 61.3 0.0 1.3e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EGO53567.1 - 7.5e-17 60.7 1.3 3.1e-16 58.7 0.9 2.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EGO53567.1 - 6.6e-09 35.2 0.0 0.0045 16.6 0.0 3.2 2 1 1 3 3 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EGO53567.1 - 7.7e-09 35.2 0.0 2.5e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EGO53567.1 - 1.2e-08 34.4 0.0 3.7e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain HlyD PF00529.15 EGO53567.1 - 1.6e-05 24.3 0.0 0.067 12.4 0.0 2.7 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 EGO53567.1 - 2.1e-05 24.4 0.0 4.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EGO53567.1 - 0.00019 21.7 0.0 0.57 10.5 0.0 3.2 2 0 0 2 2 2 2 HlyD family secretion protein RimK PF08443.6 EGO53567.1 - 0.00078 18.9 0.0 0.049 13.1 0.0 2.6 3 0 0 3 3 3 1 RimK-like ATP-grasp domain HlyD_2 PF12700.2 EGO53567.1 - 0.025 13.7 0.7 0.46 9.5 0.0 2.4 2 1 1 3 3 3 0 HlyD family secretion protein ATPgrasp_ST PF14397.1 EGO53567.1 - 0.026 13.6 0.0 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Alpha_TIF PF02232.10 EGO53567.1 - 0.073 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) GCV_H PF01597.14 EGO53567.1 - 0.099 12.3 0.2 0.29 10.8 0.1 1.8 1 0 0 1 1 1 0 Glycine cleavage H-protein CWC25 PF12542.3 EGO53568.1 - 1.6e-26 92.5 0.7 1.6e-26 92.5 0.5 4.2 4 2 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EGO53568.1 - 1.1e-09 38.0 4.3 1.1e-09 38.0 3.0 3.9 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR PCI PF01399.22 EGO53569.1 - 3e-17 62.8 0.2 1.8e-16 60.3 0.0 2.4 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EGO53569.1 - 9e-07 28.7 0.1 2.5e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_10 PF13374.1 EGO53569.1 - 0.00063 19.5 2.4 0.18 11.8 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGO53569.1 - 0.009 15.9 5.6 0.12 12.3 0.2 4.0 2 1 2 4 4 4 1 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 EGO53569.1 - 0.013 14.6 0.1 0.049 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase TPR_1 PF00515.23 EGO53569.1 - 0.017 14.7 4.0 0.75 9.5 0.5 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat P16-Arc PF04699.9 EGO53569.1 - 0.064 13.2 0.8 0.15 12.0 0.5 1.6 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) TPR_2 PF07719.12 EGO53569.1 - 0.55 10.2 9.7 0.17 11.8 0.4 4.5 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGO53569.1 - 2.2 8.0 6.1 1.1 9.0 0.2 3.4 6 0 0 6 6 6 0 TPR repeat NUDIX_4 PF14815.1 EGO53570.1 - 0.031 13.6 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 NUDIX domain Peptidase_C65 PF10275.4 EGO53572.1 - 1.5e-72 243.9 0.0 2.5e-72 243.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain BPL_LplA_LipB PF03099.14 EGO53573.1 - 4e-07 30.0 0.0 7.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Methyltrn_RNA_3 PF02598.12 EGO53574.1 - 2.6e-92 309.2 0.0 3e-92 309.0 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 EGO53574.1 - 0.064 13.1 0.0 0.94 9.3 0.0 2.1 2 0 0 2 2 2 0 SpoU rRNA Methylase family Thioredoxin PF00085.15 EGO53575.1 - 1.6e-25 88.7 0.0 2.1e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EGO53575.1 - 2.2e-06 27.8 0.1 6.2e-06 26.3 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGO53575.1 - 1.2e-05 25.3 0.0 0.0093 16.0 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 EGO53575.1 - 0.00035 20.1 0.0 0.00049 19.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EGO53575.1 - 0.00072 19.1 0.1 0.086 12.3 0.0 2.2 1 1 1 2 2 2 2 Redoxin Thioredoxin_7 PF13899.1 EGO53575.1 - 0.0077 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EGO53575.1 - 0.016 14.8 0.1 1.6 8.4 0.0 2.4 1 1 1 2 2 2 0 AhpC/TSA family HyaE PF07449.6 EGO53575.1 - 0.077 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.1 EGO53575.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.19 EGO53575.1 - 0.15 12.0 0.1 0.31 11.0 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin Rsm22 PF09243.5 EGO53576.1 - 1.4e-32 112.8 0.0 5e-32 111.0 0.0 2.1 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Ras PF00071.17 EGO53577.1 - 3.8e-54 182.4 0.0 4.4e-54 182.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO53577.1 - 5.8e-16 59.0 0.0 7.9e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO53577.1 - 1.1e-09 37.7 0.0 2.2e-09 36.7 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO53577.1 - 0.00074 18.7 0.0 0.00081 18.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGO53577.1 - 0.0053 16.0 0.0 0.0076 15.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGO53577.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 EGO53577.1 - 0.012 14.2 0.0 0.022 13.4 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.22 EGO53577.1 - 0.088 13.1 0.0 0.14 12.4 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EGO53577.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase TP_methylase PF00590.15 EGO53578.1 - 2.4e-43 148.2 0.1 4.7e-43 147.3 0.1 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EGO53578.1 - 6e-13 48.9 0.5 1.4e-12 47.7 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EGO53578.1 - 1.5e-08 33.8 0.1 1.5e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EGO53578.1 - 3.2e-05 22.8 0.0 6.8e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central GET2 PF08690.5 EGO53580.1 - 0.15 11.2 0.3 0.2 10.8 0.2 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 RTC PF01137.16 EGO53581.1 - 1.3e-31 109.1 0.0 3.3e-31 107.8 0.0 1.6 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase ThiF PF00899.16 EGO53582.1 - 1.5e-34 118.7 0.0 2.6e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 EGO53582.1 - 0.00076 18.5 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 EGO53582.1 - 0.0063 16.7 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.13 EGO53582.1 - 0.029 14.3 1.2 0.057 13.4 0.0 2.1 3 0 0 3 3 3 0 TrkA-N domain Glyco_hydro_17 PF00332.13 EGO53582.1 - 0.047 12.7 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 FAD_binding_3 PF01494.14 EGO53582.1 - 0.048 12.7 0.1 0.076 12.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 EGO53582.1 - 0.049 13.0 0.0 0.097 12.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EGO53582.1 - 0.095 12.0 0.2 0.58 9.5 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TMP_2 PF06791.8 EGO53582.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Prophage tail length tape measure protein adh_short PF00106.20 EGO53583.1 - 1.8e-33 115.8 2.2 2.4e-33 115.4 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO53583.1 - 8.2e-15 55.2 0.3 9.9e-15 54.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO53583.1 - 5.2e-11 42.5 0.7 7.2e-11 42.0 0.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EGO53583.1 - 0.00017 21.2 0.3 0.00028 20.5 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EGO53583.1 - 0.00035 20.0 0.0 0.00063 19.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.10 EGO53583.1 - 0.0012 18.5 0.6 0.0019 17.8 0.4 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.12 EGO53583.1 - 0.0046 15.8 0.2 0.0066 15.3 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.13 EGO53583.1 - 0.0069 16.3 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.10 EGO53583.1 - 0.0095 14.8 0.1 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.9 EGO53583.1 - 0.028 13.7 0.1 0.074 12.4 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 EGO53583.1 - 0.053 12.6 0.2 0.11 11.5 0.1 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EGO53583.1 - 0.055 13.8 0.1 0.23 11.9 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EGO53583.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_4 PF07993.7 EGO53583.1 - 0.074 11.9 0.1 0.13 11.1 0.1 1.5 1 1 0 1 1 1 0 Male sterility protein CBM_19 PF03427.8 EGO53584.1 - 0.35 10.6 8.6 0.64 9.8 5.9 1.5 1 1 0 1 1 1 0 Carbohydrate binding domain (family 19) Toxin_16 PF07945.6 EGO53584.1 - 1.3 8.7 8.8 0.12 12.0 0.9 2.2 2 0 0 2 2 2 0 Janus-atracotoxin AMP-binding PF00501.23 EGO53585.1 - 1.6e-88 296.9 0.0 1.9e-88 296.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO53585.1 - 5.7e-17 62.4 0.5 2.9e-16 60.1 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Gly_transf_sug PF04488.10 EGO53586.1 - 3.8e-13 49.7 0.0 8.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif EST1_DNA_bind PF10373.4 EGO53588.1 - 3.6e-13 49.3 0.1 3e-12 46.3 0.0 2.2 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain DUF1620 PF07774.8 EGO53590.1 - 4.5e-74 248.3 0.0 7.4e-74 247.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EGO53590.1 - 2.1e-11 43.7 7.6 1.1e-10 41.3 1.7 3.2 4 0 0 4 4 4 2 PQQ-like domain PQQ PF01011.16 EGO53590.1 - 0.00044 19.6 0.7 16 5.2 0.0 4.8 5 0 0 5 5 5 2 PQQ enzyme repeat LRR_4 PF12799.2 EGO53591.1 - 6.3e-13 48.0 10.6 1.5e-10 40.4 1.8 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO53591.1 - 1.2e-08 34.5 4.5 2.6e-07 30.2 4.1 2.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 EGO53591.1 - 9.3e-06 24.9 6.5 0.34 11.1 0.0 4.0 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 EGO53591.1 - 0.00035 20.2 8.6 0.25 11.7 0.4 3.6 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 EGO53591.1 - 0.0074 16.2 3.5 1.3 9.3 0.2 3.4 3 0 0 3 3 3 2 Leucine Rich repeat zf-RING_3 PF14369.1 EGO53592.1 - 0.16 11.9 0.9 2.7 8.0 0.1 2.6 2 0 0 2 2 2 0 zinc-finger Phosducin PF02114.11 EGO53593.1 - 1.3e-14 53.6 0.2 1.9e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 Phosducin Ribosomal_S27e PF01667.12 EGO53594.1 - 2.2e-28 97.5 7.4 2.7e-28 97.2 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EGO53594.1 - 0.012 15.5 1.4 0.013 15.3 1.0 1.2 1 0 0 1 1 1 0 IBR domain TF_Zn_Ribbon PF08271.7 EGO53594.1 - 0.28 10.5 3.3 0.41 10.0 2.3 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding RNR_inhib PF08591.5 EGO53595.1 - 1.3e-24 86.9 1.8 2.6e-24 85.9 0.2 2.2 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor SIP1 PF04938.7 EGO53596.1 - 0.0014 18.0 4.1 0.11 11.8 0.0 3.6 4 1 0 4 4 4 3 Survival motor neuron (SMN) interacting protein 1 (SIP1) Raptor_N PF14538.1 EGO53597.1 - 3.3e-63 212.1 0.0 6.2e-63 211.2 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EGO53597.1 - 1.6e-11 43.6 0.6 0.45 10.4 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EGO53597.1 - 4e-06 26.5 1.2 0.012 15.3 0.1 2.9 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.17 EGO53597.1 - 0.0052 16.7 0.5 0.35 11.0 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 EGO53597.1 - 0.057 13.7 0.3 0.3 11.3 0.0 2.3 3 0 0 3 3 3 0 HEAT repeats Kelch_4 PF13418.1 EGO53598.1 - 3.6e-39 132.3 8.7 3.1e-08 33.2 0.5 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EGO53598.1 - 9.7e-35 117.9 6.1 6.4e-10 38.7 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EGO53598.1 - 1.3e-32 111.2 15.1 7.7e-08 32.2 0.1 7.7 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.20 EGO53598.1 - 6.1e-32 108.9 3.4 1.9e-11 43.2 0.3 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EGO53598.1 - 1.3e-30 104.2 3.1 8.2e-12 44.7 0.4 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EGO53598.1 - 3.3e-19 67.8 8.3 4.2e-08 32.6 0.2 6.6 6 1 0 6 6 6 4 Kelch motif IncA PF04156.9 EGO53598.1 - 0.0016 18.1 13.2 0.0016 18.1 9.2 6.2 3 1 2 6 6 6 1 IncA protein IFT57 PF10498.4 EGO53598.1 - 0.0029 16.4 14.1 0.0029 16.4 9.8 3.3 2 1 1 3 3 3 1 Intra-flagellar transport protein 57 Filament PF00038.16 EGO53598.1 - 0.0034 16.9 34.8 0.0034 16.9 24.1 4.4 2 1 3 5 5 5 2 Intermediate filament protein RAG2 PF03089.9 EGO53598.1 - 0.12 11.0 0.2 3.2 6.3 0.0 3.1 4 0 0 4 4 4 0 Recombination activating protein 2 GAS PF13851.1 EGO53598.1 - 7.5 5.6 83.1 0.11 11.6 9.0 4.7 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding Mpv17_PMP22 PF04117.7 EGO53599.1 - 2.7e-16 58.9 6.2 2.7e-16 58.9 4.3 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family YIF1 PF03878.10 EGO53600.1 - 7.8e-77 257.6 2.4 1e-76 257.2 1.7 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EGO53600.1 - 0.00079 18.9 5.6 0.00079 18.9 3.9 1.6 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.8 EGO53601.1 - 2.7e-81 273.0 0.0 3.7e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EGO53601.1 - 5.7e-53 179.2 0.3 9.7e-53 178.5 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EGO53601.1 - 8.4e-08 32.2 0.7 3e-07 30.4 0.2 2.2 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EGO53601.1 - 2.1e-05 23.4 0.0 4.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 EGO53601.1 - 0.00069 19.0 0.2 0.0021 17.5 0.1 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EGO53601.1 - 0.014 15.0 0.1 0.053 13.2 0.1 2.0 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGO53601.1 - 0.015 15.2 0.0 0.059 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 EGO53601.1 - 0.02 14.8 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EGO53601.1 - 0.058 13.6 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter PI3_PI4_kinase PF00454.22 EGO53602.1 - 6.8e-48 163.1 0.0 1.4e-47 162.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EGO53602.1 - 5.6e-45 153.8 0.5 1.1e-44 152.9 0.4 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.8 EGO53602.1 - 1.9e-31 108.1 0.0 7e-31 106.3 0.0 2.1 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.15 EGO53602.1 - 1.2e-17 62.9 0.4 3.5e-17 61.5 0.0 2.1 2 0 0 2 2 2 1 FATC domain TPR_16 PF13432.1 EGO53602.1 - 4.9e-05 23.8 2.9 0.7 10.6 0.3 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGO53602.1 - 0.00044 19.8 0.5 0.97 9.3 0.1 3.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGO53602.1 - 0.0012 19.2 1.0 1.6 9.3 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGO53602.1 - 0.0016 18.0 4.0 1.6 8.4 0.2 3.9 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.1 EGO53602.1 - 0.0022 18.3 10.7 0.16 12.3 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGO53602.1 - 0.0027 18.1 12.6 1.6 9.5 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EGO53602.1 - 0.0065 16.5 0.2 0.14 12.2 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGO53602.1 - 0.014 15.2 5.3 1.3 8.9 0.2 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGO53602.1 - 0.46 10.5 3.7 6.1 7.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-PARP PF00645.13 EGO53603.1 - 5.8e-21 74.5 0.3 1.8e-20 72.9 0.2 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Med17 PF10156.4 EGO53605.1 - 4.5e-104 348.3 0.0 5.3e-104 348.0 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.15 EGO53606.1 - 6.6e-160 530.5 0.6 1.8e-115 384.7 0.9 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.14 EGO53606.1 - 0.15 11.6 0.3 0.43 10.1 0.2 1.8 1 0 0 1 1 1 0 UvrB/uvrC motif SKG6 PF08693.5 EGO53607.1 - 0.00048 19.3 0.4 0.001 18.3 0.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1517 PF07466.6 EGO53607.1 - 0.065 12.2 7.3 0.11 11.4 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) SNF2_N PF00176.18 EGO53608.1 - 1.2e-70 237.7 1.2 2.2e-70 236.8 0.8 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO53608.1 - 1.3e-09 37.7 0.0 3.2e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EGO53608.1 - 1.7e-09 37.1 2.2 3e-09 36.4 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO53608.1 - 8.4e-09 35.3 4.0 1.7e-08 34.3 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO53608.1 - 1.5e-08 34.2 3.1 3e-08 33.3 2.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGO53608.1 - 1.3e-07 31.1 3.0 2.6e-07 30.1 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO53608.1 - 6.6e-07 28.9 2.4 1.3e-06 28.0 1.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGO53608.1 - 2.9e-06 26.8 0.9 7.8e-06 25.5 0.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.10 EGO53608.1 - 6.6e-06 26.0 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.1 EGO53608.1 - 3.1e-05 23.7 3.9 9.2e-05 22.2 2.7 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 EGO53608.1 - 0.0012 18.5 0.5 0.0031 17.2 0.3 1.7 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 EGO53608.1 - 0.009 15.5 3.4 0.042 13.4 2.5 2.0 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 EGO53608.1 - 0.017 14.6 2.2 0.052 13.0 1.6 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 EGO53608.1 - 0.22 11.3 1.6 2.1 8.2 0.3 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EGO53608.1 - 0.28 10.7 8.6 2.6 7.6 3.5 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Phosphodiest PF01663.17 EGO53609.1 - 2.5e-90 303.4 0.3 3.6e-90 302.9 0.2 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGO53609.1 - 0.00033 19.9 0.1 0.0046 16.1 0.0 2.2 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.7 EGO53609.1 - 0.14 11.7 0.7 0.93 9.1 0.1 2.3 2 0 0 2 2 2 0 PglZ domain Acetyltransf_9 PF13527.1 EGO53610.1 - 4.7e-07 29.7 0.0 7.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGO53610.1 - 3.2e-05 23.9 0.0 5.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO53610.1 - 9.4e-05 22.5 0.1 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO53610.1 - 0.00075 19.4 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.1 EGO53610.1 - 0.017 14.8 0.0 0.053 13.2 0.0 1.8 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Ribosomal_L14e PF01929.12 EGO53611.1 - 8.2e-29 99.7 2.4 1.1e-28 99.3 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 NAC PF01849.13 EGO53612.1 - 6.4e-26 89.6 0.3 6.5e-25 86.4 0.1 2.4 2 0 0 2 2 2 1 NAC domain Mt_ATP-synt_D PF05873.7 EGO53612.1 - 1.1e-17 64.0 1.9 1.3e-17 63.8 0.7 1.5 1 1 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) UBA PF00627.26 EGO53612.1 - 0.0024 17.6 0.2 0.0089 15.8 0.1 2.0 1 0 0 1 1 1 1 UBA/TS-N domain T2SM_b PF10741.4 EGO53612.1 - 0.12 12.0 1.1 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b Peptidase_S64 PF08192.6 EGO53612.1 - 1.1 7.5 7.7 1.9 6.7 5.4 1.3 1 0 0 1 1 1 0 Peptidase family S64 COX16 PF14138.1 EGO53617.1 - 1.5e-33 114.7 0.3 2.2e-33 114.2 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Glyco_hydro_35 PF01301.14 EGO53618.1 - 4.8e-94 315.2 0.0 6.6e-94 314.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EGO53618.1 - 1.3e-61 207.1 1.5 2e-61 206.5 1.1 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EGO53618.1 - 1.1e-54 183.4 5.2 1.5e-29 102.4 0.6 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EGO53618.1 - 5.9e-22 76.8 0.1 1.5e-21 75.5 0.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_2_N PF02837.13 EGO53618.1 - 0.024 14.2 0.0 0.061 12.8 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain ADH_N PF08240.7 EGO53619.1 - 1.8e-26 92.0 3.5 3.6e-26 91.0 2.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO53619.1 - 8.5e-16 57.6 0.0 1.3e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 EGO53619.1 - 0.02 14.6 0.1 0.4 10.4 0.0 2.5 2 0 0 2 2 2 0 S1-like ATP-synt_G PF04718.10 EGO53620.1 - 5.2e-27 94.5 0.5 1.3e-26 93.2 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Senescence PF06911.7 EGO53620.1 - 0.0048 16.6 2.1 0.025 14.2 0.9 2.1 2 0 0 2 2 2 1 Senescence-associated protein Tape_meas_lam_C PF09718.5 EGO53620.1 - 1.1 9.2 4.6 2.5 8.0 0.9 2.3 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Methyltransf_23 PF13489.1 EGO53622.1 - 7.6e-14 51.7 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO53622.1 - 0.00013 22.3 0.0 0.00028 21.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO53622.1 - 0.00027 20.5 0.0 0.0025 17.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO53622.1 - 0.00033 21.2 0.0 0.0075 16.8 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO53622.1 - 0.00053 20.4 0.0 0.0035 17.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO53622.1 - 0.0044 16.4 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EGO53622.1 - 0.066 12.3 0.0 0.14 11.2 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGO53622.1 - 0.14 12.5 0.0 0.43 10.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain AA_permease_2 PF13520.1 EGO53623.1 - 7.5e-48 163.1 43.2 1e-47 162.6 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO53623.1 - 7.5e-24 83.9 35.2 1e-23 83.4 24.4 1.1 1 0 0 1 1 1 1 Amino acid permease PixA PF12306.3 EGO53623.1 - 3.5 7.4 5.1 28 4.4 0.0 2.3 2 0 0 2 2 2 0 Inclusion body protein NAPRTase PF04095.11 EGO53624.1 - 7.2e-53 179.3 0.1 5.5e-52 176.4 0.1 1.9 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family WD40 PF00400.27 EGO53625.1 - 6.5e-10 38.5 14.9 0.00069 19.4 0.0 9.1 9 1 0 9 9 9 1 WD domain, G-beta repeat PQQ_2 PF13360.1 EGO53625.1 - 1.1e-07 31.5 0.1 8.3e-07 28.7 0.0 2.5 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 EGO53625.1 - 0.0083 15.6 0.0 0.59 9.7 0.0 2.7 2 0 0 2 2 2 1 PQQ enzyme repeat YqfD PF06898.6 EGO53625.1 - 0.13 10.9 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Ribosomal_L25p PF01386.14 EGO53625.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal L25p family Sigma70_ner PF04546.8 EGO53625.1 - 10 5.6 11.4 1.4 8.5 0.6 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Rad4 PF03835.10 EGO53626.1 - 6.8e-14 51.4 1.1 1.8e-13 50.0 0.8 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EGO53626.1 - 3.2e-12 46.6 3.0 7.2e-12 45.5 2.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Pept_tRNA_hydro PF01195.14 EGO53627.1 - 0.088 12.2 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase Asp_protease_2 PF13650.1 EGO53628.1 - 0.00011 22.5 0.0 0.00026 21.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease PI3_PI4_kinase PF00454.22 EGO53630.1 - 1.5e-44 152.2 0.0 3.5e-43 147.7 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EGO53630.1 - 3.1e-39 134.0 1.9 6e-27 94.0 0.2 2.3 1 1 1 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 EGO53630.1 - 2.9e-31 108.1 0.0 4.9e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF928 PF06051.7 EGO53630.1 - 0.1 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) Nse4_C PF08743.5 EGO53631.1 - 4.5e-33 113.1 0.0 9.1e-33 112.1 0.0 1.5 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EGO53631.1 - 9.9e-18 63.7 0.0 3.9e-17 61.8 0.0 2.1 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF4336 PF14234.1 EGO53632.1 - 3e-14 52.9 0.0 1.1e-09 37.8 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) Amidase PF01425.16 EGO53633.1 - 1.1e-97 327.6 0.1 1.8e-97 326.9 0.0 1.3 1 1 0 1 1 1 1 Amidase RskA PF10099.4 EGO53634.1 - 0.047 13.4 0.2 0.069 12.8 0.1 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4131 PF13567.1 EGO53634.1 - 0.055 12.8 1.1 0.28 10.5 1.6 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) PRP38 PF03371.10 EGO53635.1 - 3.3e-65 218.9 0.0 4.1e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.2 EGO53635.1 - 0.0079 16.6 25.8 0.017 15.6 17.9 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term APC_CDC26 PF10471.4 EGO53635.1 - 0.013 16.1 5.6 0.025 15.3 3.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF1777 PF08648.7 EGO53635.1 - 2.9 7.6 25.3 5.4 6.7 17.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) CDC45 PF02724.9 EGO53635.1 - 5 5.0 7.8 6.4 4.6 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SOBP PF15279.1 EGO53636.1 - 0.25 11.6 11.7 0.3 11.4 8.1 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein YABBY PF04690.8 EGO53636.1 - 3.1 8.0 12.2 2 8.6 7.1 1.6 1 1 1 2 2 2 0 YABBY protein ER-remodelling PF14755.1 EGO53636.1 - 6.3 6.8 9.1 1.7 8.6 3.9 1.8 1 1 1 2 2 2 0 Intracellular membrane remodeller zf-P11 PF03854.9 EGO53637.1 - 0.0029 17.0 2.2 0.0044 16.4 1.5 1.2 1 0 0 1 1 1 1 P-11 zinc finger Metallophos PF00149.23 EGO53639.1 - 3.4e-08 33.1 3.8 6.5e-08 32.2 2.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase B12-binding PF02310.14 EGO53639.1 - 0.0049 16.7 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 B12 binding domain Macoilin PF09726.4 EGO53640.1 - 2 6.5 9.6 2.6 6.2 6.6 1.2 1 0 0 1 1 1 0 Transmembrane protein ATP-synt_C PF00137.16 EGO53641.1 - 2e-25 88.4 31.1 5.1e-15 55.1 5.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Birna_VP4 PF01768.11 EGO53641.1 - 0.097 11.7 0.7 0.15 11.1 0.5 1.3 1 0 0 1 1 1 0 Birnavirus VP4 protein CNH PF00780.17 EGO53642.1 - 2.9e-81 272.9 0.0 5.7e-81 271.9 0.0 1.5 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EGO53642.1 - 1e-42 145.2 0.0 1.9e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EGO53642.1 - 1.9e-35 122.3 0.0 3.2e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EGO53642.1 - 4e-15 55.2 0.1 7.2e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GTP_EFTU PF00009.22 EGO53643.1 - 4.9e-38 130.4 0.0 8.8e-38 129.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EGO53643.1 - 2.2e-36 123.7 0.3 4.5e-36 122.7 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EGO53643.1 - 1.5e-10 41.0 0.3 3.6e-10 39.8 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGO53643.1 - 0.0077 16.1 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Connexin_CCC PF10582.4 EGO53643.1 - 0.11 12.3 0.4 0.27 11.0 0.3 1.6 1 0 0 1 1 1 0 Gap junction channel protein cysteine-rich domain DUF202 PF02656.10 EGO53644.1 - 0.035 14.3 0.4 0.035 14.3 0.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF202) PgaD PF13994.1 EGO53644.1 - 0.11 12.0 1.1 0.18 11.2 0.1 1.9 2 0 0 2 2 2 0 PgaD-like protein DUF4131 PF13567.1 EGO53644.1 - 0.16 11.3 1.0 0.43 9.9 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3899 PF13038.1 EGO53644.1 - 0.79 9.9 5.8 3 8.0 1.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) DUF2207 PF09972.4 EGO53644.1 - 5.1 5.5 5.7 4.6 5.6 0.8 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) ADK PF00406.17 EGO53645.1 - 2.1e-44 151.0 0.0 2.5e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 EGO53645.1 - 3.1e-07 31.2 0.0 4.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO53645.1 - 5.6e-07 29.9 0.0 1e-06 29.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO53645.1 - 7.7e-06 25.8 0.1 4.5e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EGO53645.1 - 0.00014 21.2 0.2 0.072 12.4 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_19 PF13245.1 EGO53645.1 - 0.13 12.0 0.0 0.82 9.4 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain PCI PF01399.22 EGO53646.1 - 2.2e-15 56.8 0.4 2.7e-14 53.3 0.0 2.7 3 1 0 3 3 3 1 PCI domain Nucleopor_Nup85 PF07575.8 EGO53646.1 - 0.0089 14.2 0.2 0.013 13.7 0.1 1.2 1 0 0 1 1 1 1 Nup85 Nucleoporin BCAS2 PF05700.6 EGO53646.1 - 0.017 14.5 0.5 0.034 13.6 0.4 1.4 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF3256 PF11644.3 EGO53646.1 - 0.059 12.8 0.7 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3256) Pkinase PF00069.20 EGO53647.1 - 2.1e-77 259.7 0.0 2.9e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO53647.1 - 1.9e-37 128.7 0.0 2.4e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EGO53647.1 - 5.1e-16 58.5 0.3 1.5e-15 57.0 0.1 1.9 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EGO53647.1 - 2e-10 40.1 0.0 3.7e-09 35.9 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 EGO53647.1 - 0.0058 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EGO53647.1 - 0.022 13.5 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EGO53647.1 - 0.041 13.5 0.9 0.22 11.2 0.1 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EGO53647.1 - 0.18 11.1 0.3 0.55 9.5 0.1 1.9 1 1 1 2 2 2 0 RIO1 family HAMP PF00672.20 EGO53648.1 - 1.3e-47 159.7 21.1 2.8e-10 40.2 0.2 7.6 7 1 1 8 8 8 6 HAMP domain HATPase_c PF02518.21 EGO53648.1 - 1.4e-29 102.0 0.8 3.7e-29 100.6 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGO53648.1 - 1.3e-27 95.9 0.9 2.1e-26 92.1 0.3 2.9 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EGO53648.1 - 4e-18 65.1 0.5 4e-18 65.1 0.4 4.2 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 EGO53648.1 - 0.0026 16.3 19.2 0.096 11.1 0.2 3.9 1 1 2 4 4 4 4 AAA domain DUF883 PF05957.8 EGO53648.1 - 0.09 13.1 17.8 0.97 9.8 0.1 6.3 6 1 1 7 7 7 0 Bacterial protein of unknown function (DUF883) DUF2365 PF10157.4 EGO53648.1 - 0.12 12.2 12.8 9.3 6.1 0.0 6.5 5 1 2 7 7 7 0 Uncharacterized conserved protein (DUF2365) NAAA-beta PF15508.1 EGO53648.1 - 0.19 12.1 5.3 7.9 6.9 0.1 5.6 4 2 3 7 7 7 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase GRP PF07172.6 EGO53649.1 - 2 8.9 19.0 0.81 10.2 9.4 2.2 2 0 0 2 2 2 0 Glycine rich protein family HMG_box PF00505.14 EGO53651.1 - 1e-18 67.3 1.9 2.3e-18 66.2 1.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO53651.1 - 3.1e-15 56.2 1.7 8e-15 54.9 1.2 1.7 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 EGO53651.1 - 1.1e-08 35.1 0.0 1.9e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGO53651.1 - 2.6e-06 27.1 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NCD1 PF04904.8 EGO53651.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) DUF3396 PF11876.3 EGO53653.1 - 0.085 11.9 0.0 0.085 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3396) Mito_fiss_reg PF05308.6 EGO53655.1 - 0.01 15.1 0.7 0.013 14.8 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Na_Ca_ex PF01699.19 EGO53656.1 - 1.8e-42 144.2 36.7 1.5e-22 79.7 6.5 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cnd2 PF05786.9 EGO53657.1 - 7.7e-201 669.3 10.3 1.5e-200 668.4 7.2 1.4 1 1 0 1 1 1 1 Condensin complex subunit 2 Nsp1_C PF05064.8 EGO53659.1 - 3.3e-42 142.8 4.7 7.9e-42 141.5 3.2 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EGO53659.1 - 2.2e-26 92.3 212.0 6.4e-09 36.0 30.2 5.9 1 1 4 5 5 5 4 Nucleoporin FG repeat region EzrA PF06160.7 EGO53659.1 - 0.007 14.6 8.2 0.021 13.0 0.0 2.0 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA Tropomyosin_1 PF12718.2 EGO53659.1 - 0.11 12.3 5.3 2.4 8.0 3.1 2.3 2 0 0 2 2 2 0 Tropomyosin like MscS_porin PF12795.2 EGO53659.1 - 0.41 9.9 9.9 0.17 11.1 3.2 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Myosin_tail_1 PF01576.14 EGO53659.1 - 0.48 8.0 8.7 0.98 7.0 2.5 2.0 2 0 0 2 2 2 0 Myosin tail APG6 PF04111.7 EGO53659.1 - 0.76 8.7 7.3 0.55 9.2 2.9 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 EGO53659.1 - 1.8 8.1 6.1 5.9 6.4 4.2 1.8 1 1 0 1 1 1 0 IncA protein TACC PF05010.9 EGO53659.1 - 2.1 8.0 7.0 34 4.1 3.4 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) AAA_13 PF13166.1 EGO53659.1 - 4.4 5.6 6.9 6.9 5.0 3.5 1.7 1 1 0 1 1 1 0 AAA domain V-SNARE PF05008.10 EGO53659.1 - 7.9 6.7 7.3 4.7 7.4 0.9 3.0 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus IATP PF04568.7 EGO53660.1 - 4.2e-20 71.6 0.2 4.9e-20 71.4 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF489 PF04356.7 EGO53660.1 - 0.09 12.3 0.4 0.12 11.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF349 PF03993.7 EGO53660.1 - 0.24 11.5 5.4 0.34 11.0 3.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) DivIC PF04977.10 EGO53660.1 - 0.47 9.9 3.5 0.68 9.4 2.4 1.3 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 EGO53660.1 - 0.52 9.8 3.1 0.64 9.5 2.2 1.1 1 0 0 1 1 1 0 IncA protein FYVE_2 PF02318.11 EGO53660.1 - 0.76 9.6 3.0 1 9.3 2.1 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger 14-3-3 PF00244.15 EGO53661.1 - 1.5e-116 387.5 4.0 1.7e-116 387.3 2.8 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.1 EGO53661.1 - 0.21 11.9 2.4 2.5 8.5 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-CSL PF05207.8 EGO53662.1 - 7.6e-16 57.3 0.7 1.2e-15 56.7 0.5 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EGO53662.1 - 1.6e-13 50.1 0.1 1.5e-12 47.0 0.1 2.1 1 1 0 1 1 1 1 DnaJ domain SR-25 PF10500.4 EGO53662.1 - 1.1 8.6 8.1 1.6 8.1 5.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DEAD PF00270.24 EGO53664.1 - 1.7e-41 141.5 0.0 4.9e-40 136.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO53664.1 - 1.5e-25 88.8 0.1 3.5e-25 87.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO53664.1 - 0.039 13.7 0.9 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Mito_carr PF00153.22 EGO53665.1 - 4.2e-63 209.0 0.0 9.1e-22 76.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TspO_MBR PF03073.10 EGO53666.1 - 1.6e-38 131.5 6.0 2.3e-38 131.0 4.2 1.2 1 0 0 1 1 1 1 TspO/MBR family DUF3546 PF12066.3 EGO53667.1 - 6.1e-29 100.2 1.9 6.1e-29 100.2 1.3 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 EGO53667.1 - 1.2e-24 85.6 0.1 2.9e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 EGO53667.1 - 2.5e-11 44.2 0.7 2.5e-11 44.2 0.5 1.8 2 0 0 2 2 2 1 Arsenite-resistance protein 2 FolB PF02152.13 EGO53668.1 - 1.7e-20 73.2 0.0 4.3e-17 62.2 0.0 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase RXT2_N PF08595.6 EGO53668.1 - 0.051 13.3 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal UDPGP PF01704.13 EGO53669.1 - 3.4e-185 615.5 0.4 3.9e-185 615.3 0.3 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ING PF12998.2 EGO53670.1 - 2.3e-22 79.2 7.3 4.3e-22 78.3 5.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EGO53670.1 - 6e-08 32.2 8.8 9.8e-08 31.5 6.1 1.3 1 0 0 1 1 1 1 PHD-finger Mnd1 PF03962.10 EGO53670.1 - 0.12 11.9 4.3 0.21 11.2 3.0 1.3 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 EGO53670.1 - 3.5 7.1 6.1 7.8 6.0 4.2 1.5 1 1 0 1 1 1 0 IncA protein Hist_deacetyl PF00850.14 EGO53671.1 - 5.5e-77 259.1 0.1 8.5e-77 258.4 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Apc1 PF12859.2 EGO53671.1 - 0.11 12.6 0.1 0.8 9.9 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 WW PF00397.21 EGO53673.1 - 8.4e-10 38.3 0.1 3.3e-09 36.4 0.1 2.2 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 EGO53673.1 - 0.00088 17.9 1.3 0.0076 14.8 0.5 2.1 2 0 0 2 2 2 1 PhoD-like phosphatase MFS_1 PF07690.11 EGO53674.1 - 1.1e-15 57.2 11.5 1.1e-15 57.2 8.0 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily HGWP PF03578.10 EGO53676.1 - 2.5 7.5 0.5 1.8e+02 1.5 0.0 4.3 5 0 0 5 5 5 0 HGWP repeat Fib_alpha PF08702.5 EGO53676.1 - 3.5 7.7 15.1 1.7 8.7 7.9 2.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Glyco_hydro_47 PF01532.15 EGO53677.1 - 4.4e-169 562.9 0.0 7.1e-169 562.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Borrelia_P83 PF05262.6 EGO53677.1 - 1.3 7.1 6.7 2 6.6 4.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Autophagy_act_C PF03987.10 EGO53678.1 - 0.0018 18.3 0.0 0.0039 17.3 0.0 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_5 PF13893.1 EGO53679.1 - 2.5e-10 40.0 0.0 3.9e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO53679.1 - 6.6e-09 35.2 0.0 1.8e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EGO53679.1 - 2.7e-05 23.8 0.0 5.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Calcipressin RRM_6 PF14259.1 EGO53679.1 - 3.6e-05 23.6 0.0 7.3e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2360 PF10152.4 EGO53679.1 - 0.062 13.5 1.7 0.094 13.0 1.2 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF4523 PF15023.1 EGO53679.1 - 0.082 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Nsp3_PL2pro PF12124.3 EGO53679.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain WD40 PF00400.27 EGO53680.1 - 2.2e-20 71.6 10.7 1e-06 28.3 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Rax2 PF12768.2 EGO53680.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Gmad1 PF10647.4 EGO53680.1 - 0.092 12.1 0.1 3.5 6.9 0.0 2.6 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Collagen PF01391.13 EGO53681.1 - 0.00033 20.1 13.6 0.00072 19.0 9.4 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) AA_permease PF00324.16 EGO53682.1 - 1.7e-132 442.1 40.7 2.2e-132 441.8 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO53682.1 - 7e-37 126.9 42.1 9.4e-37 126.5 29.2 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EGO53683.1 - 1.1e-20 73.6 19.3 1.1e-20 73.6 13.4 2.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Herpes_UL95 PF03038.9 EGO53683.1 - 0.065 12.0 0.0 0.098 11.5 0.0 1.1 1 0 0 1 1 1 0 UL95 family Sugar_tr PF00083.19 EGO53683.1 - 0.15 10.6 12.5 0.037 12.6 6.1 1.8 2 0 0 2 2 2 0 Sugar (and other) transporter MFS_3 PF05977.8 EGO53683.1 - 0.9 7.5 11.8 0.021 12.9 3.2 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector UBA_4 PF14555.1 EGO53684.1 - 0.0026 17.2 0.0 0.0056 16.1 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain DUF1690 PF07956.6 EGO53684.1 - 0.1 12.5 2.4 0.13 12.2 1.7 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DAHP_synth_2 PF01474.11 EGO53685.1 - 4.1e-194 644.9 0.0 4.6e-194 644.8 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Ca_chan_IQ PF08763.6 EGO53685.1 - 0.015 14.5 0.1 0.032 13.4 0.1 1.5 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain Aldose_epim PF01263.15 EGO53686.1 - 1.1e-36 126.4 0.0 6.2e-20 71.4 0.0 2.0 2 0 0 2 2 2 2 Aldose 1-epimerase Zn_clus PF00172.13 EGO53687.1 - 7.6e-07 28.9 10.4 1.7e-06 27.8 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 EGO53687.1 - 7.8e-06 25.9 2.3 0.12 12.7 0.1 3.3 1 1 1 2 2 2 2 Zinc finger, C2H2 type Ric8 PF10165.4 EGO53688.1 - 9.8e-139 462.9 0.0 1.2e-138 462.7 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.3 EGO53689.1 - 4.3e-135 450.4 2.3 5.8e-135 450.0 1.6 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal MBOAT_2 PF13813.1 EGO53690.1 - 3.4e-13 49.4 0.2 3.4e-13 49.4 0.1 3.2 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Telomerase_RBD PF12009.3 EGO53691.1 - 5.8e-45 152.5 0.4 1.2e-44 151.4 0.3 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EGO53691.1 - 1.3e-13 50.7 0.8 3e-12 46.3 0.5 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGEF PF00621.15 EGO53692.1 - 2.3e-33 115.5 0.0 5.8e-33 114.2 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 EGO53692.1 - 8.7e-15 54.8 1.7 2.4e-14 53.3 1.2 1.7 1 0 0 1 1 1 1 BAR domain Aminotran_5 PF00266.14 EGO53694.1 - 1.4e-29 102.9 0.0 1.8e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 EGO53694.1 - 4.2e-20 71.6 0.0 8.1e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain AAA_16 PF13191.1 EGO53695.1 - 3.2e-15 56.6 0.8 1.1e-14 54.8 0.0 2.3 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGO53695.1 - 2.6e-13 50.2 0.0 5.6e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EGO53695.1 - 4.1e-08 33.5 0.0 9.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EGO53695.1 - 5e-06 26.2 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Cdc6_C PF09079.6 EGO53695.1 - 8.6e-05 22.1 0.0 0.00031 20.4 0.0 1.9 2 0 0 2 2 2 1 CDC6, C terminal NB-ARC PF00931.17 EGO53695.1 - 8.9e-05 21.4 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 EGO53695.1 - 0.00029 20.5 0.0 0.00056 19.6 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase DUF2075 PF09848.4 EGO53695.1 - 0.0011 18.0 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 EGO53695.1 - 0.002 18.0 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EGO53695.1 - 0.0042 16.1 0.2 0.017 14.1 0.2 2.1 1 1 0 1 1 1 1 KAP family P-loop domain AAA_17 PF13207.1 EGO53695.1 - 0.0051 17.6 0.0 0.011 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EGO53695.1 - 0.0063 16.2 0.1 0.018 14.7 0.1 1.8 1 1 0 1 1 1 1 NTPase AAA_19 PF13245.1 EGO53695.1 - 0.0069 16.1 0.1 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain MMR_HSR1 PF01926.18 EGO53695.1 - 0.01 15.7 0.1 0.03 14.2 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 EGO53695.1 - 0.019 15.0 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EGO53695.1 - 0.024 14.2 0.0 0.061 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EGO53695.1 - 0.024 13.5 0.0 0.075 11.9 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 EGO53695.1 - 0.033 13.8 0.0 0.09 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EGO53695.1 - 0.043 14.1 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Velvet PF11754.3 EGO53696.1 - 5.1e-49 166.6 0.1 4.2e-47 160.3 0.0 2.2 2 0 0 2 2 2 2 Velvet factor DUF3602 PF12223.3 EGO53697.1 - 3.1e-17 62.7 18.3 5.1e-14 52.4 1.6 4.4 2 1 3 5 5 5 3 Protein of unknown function (DUF3602) PRTP PF01366.13 EGO53697.1 - 5.4 4.8 7.0 6.8 4.5 4.9 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein URO-D PF01208.12 EGO53698.1 - 1.1e-124 415.8 0.0 1.3e-124 415.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Zn_clus PF00172.13 EGO53701.1 - 1.4e-06 28.0 13.7 2.6e-06 27.2 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 EGO53704.1 - 1.9e-09 37.8 0.1 2.9e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 EGO53705.1 - 3.9e-12 46.1 0.0 7.3e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGO53705.1 - 1.6e-09 37.9 0.1 3.4e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGO53705.1 - 0.0021 17.7 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EGO53705.1 - 0.0029 17.7 0.0 0.0097 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGO53705.1 - 0.0076 17.0 0.8 0.15 12.9 0.2 3.0 2 1 0 2 2 1 1 AAA domain AAA PF00004.24 EGO53705.1 - 0.0085 16.2 0.0 0.043 14.0 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EGO53705.1 - 0.0094 16.1 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.1 EGO53705.1 - 0.0097 15.4 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EGO53705.1 - 0.011 14.6 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.15 EGO53705.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 EGO53705.1 - 0.028 14.7 0.1 0.12 12.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EGO53705.1 - 0.068 12.1 0.8 0.17 10.8 0.3 1.6 1 1 0 1 1 1 0 KAP family P-loop domain NTPase_1 PF03266.10 EGO53705.1 - 0.071 12.8 0.0 0.42 10.2 0.0 2.1 2 0 0 2 2 2 0 NTPase CbiA PF01656.18 EGO53705.1 - 0.13 11.6 0.1 0.51 9.7 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PIF1 PF05970.9 EGO53705.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase PNP_UDP_1 PF01048.15 EGO53706.1 - 0.0063 15.5 0.0 0.0072 15.3 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily K_channel_TID PF07941.6 EGO53707.1 - 0.032 14.4 14.6 0.097 12.9 2.5 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Dynamin_N PF00350.18 EGO53710.1 - 0.028 14.2 7.2 0.29 10.9 5.7 2.1 2 0 0 2 2 2 0 Dynamin family Ycf1 PF05758.7 EGO53710.1 - 0.033 11.9 10.9 0.047 11.4 7.6 1.2 1 0 0 1 1 1 0 Ycf1 LMBR1 PF04791.11 EGO53710.1 - 0.29 9.6 3.6 0.44 9.0 2.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-C2H2_4 PF13894.1 EGO53710.1 - 0.32 11.4 14.7 0.81 10.1 0.2 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger AAA_23 PF13476.1 EGO53710.1 - 0.72 10.1 24.2 1.7 8.9 16.8 1.6 1 0 0 1 1 1 0 AAA domain Glyco_transf_15 PF01793.11 EGO53710.1 - 2 7.2 11.4 3.6 6.4 7.9 1.4 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Mem_trans PF03547.13 EGO53710.1 - 2.1 6.5 4.5 3.4 5.8 3.1 1.3 1 0 0 1 1 1 0 Membrane transport protein VCBS PF13517.1 EGO53712.1 - 3.9e-13 49.5 9.3 3.5e-06 27.2 0.8 2.9 2 1 1 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EGO53712.1 - 0.00024 20.6 2.0 1.3 8.7 0.0 3.4 3 0 0 3 3 3 2 FG-GAP repeat MFS_1 PF07690.11 EGO53713.1 - 3.1e-11 42.6 2.6 3.8e-11 42.3 1.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO53713.1 - 0.005 15.4 0.7 0.0052 15.4 0.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF423 PF04241.10 EGO53713.1 - 0.036 13.9 0.2 0.1 12.5 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF423) MAPEG PF01124.13 EGO53714.1 - 1.8e-25 89.0 0.6 2.1e-25 88.7 0.4 1.1 1 0 0 1 1 1 1 MAPEG family Kelch_5 PF13854.1 EGO53715.1 - 2.4e-08 33.7 10.5 5.8e-07 29.3 0.1 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EGO53715.1 - 0.0001 21.8 2.3 0.44 10.4 0.0 3.9 3 0 0 3 3 3 2 Kelch motif SKG6 PF08693.5 EGO53715.1 - 0.0014 17.8 0.2 0.0027 16.9 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_6 PF13964.1 EGO53715.1 - 0.019 15.1 3.7 0.27 11.5 0.1 3.9 4 0 0 4 4 4 0 Kelch motif EphA2_TM PF14575.1 EGO53715.1 - 0.039 14.3 0.0 0.093 13.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Kelch_1 PF01344.20 EGO53715.1 - 0.19 11.2 8.3 0.28 10.7 0.1 3.5 3 1 0 3 3 3 0 Kelch motif DUF1183 PF06682.7 EGO53715.1 - 0.52 9.8 14.7 0.19 11.3 5.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) HET PF06985.6 EGO53716.1 - 1e-19 71.0 0.0 1.8e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UFD1 PF03152.9 EGO53716.1 - 0.0078 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Glyco_hydro_71 PF03659.9 EGO53718.1 - 2.7e-134 447.4 8.4 3.7e-134 447.0 5.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF1512 PF07431.7 EGO53718.1 - 0.019 13.6 0.4 0.03 13.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) MOSC PF03473.12 EGO53722.1 - 6.1e-10 38.6 0.8 5.1e-05 22.7 0.0 2.5 2 1 0 2 2 2 2 MOSC domain TPR_10 PF13374.1 EGO53723.1 - 4.5e-41 137.6 0.1 5.8e-11 41.9 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGO53723.1 - 1.5e-34 117.7 2.4 6.3e-13 48.4 0.0 4.3 1 1 4 5 5 5 5 Tetratricopeptide repeat NB-ARC PF00931.17 EGO53723.1 - 3.3e-09 36.0 0.0 6.1e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.1 EGO53723.1 - 2.5e-08 33.1 0.7 0.0076 15.9 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 EGO53723.1 - 2.3e-07 30.5 0.3 0.72 10.4 0.2 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGO53723.1 - 2.7e-07 30.1 0.0 0.081 12.5 0.0 3.8 1 1 3 4 4 4 4 TPR repeat TPR_14 PF13428.1 EGO53723.1 - 1.6e-06 28.2 0.5 9.2 7.2 0.0 5.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGO53723.1 - 7.8e-06 25.4 1.5 0.83 9.7 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGO53723.1 - 1.8e-05 24.1 0.1 0.36 10.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat NACHT PF05729.7 EGO53723.1 - 7.3e-05 22.4 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_16 PF13432.1 EGO53723.1 - 7.8e-05 23.2 6.8 0.22 12.2 0.1 4.5 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO53723.1 - 0.00013 22.2 0.1 0.8 10.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO53723.1 - 0.0038 17.3 0.6 0.6 10.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.1 EGO53723.1 - 0.0041 17.2 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_6 PF13174.1 EGO53723.1 - 0.036 14.5 0.8 42 4.9 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGO53723.1 - 0.037 13.8 0.1 2.4 8.1 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EGO53723.1 - 0.052 13.6 0.1 0.76 9.9 0.0 3.0 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TCTP PF00838.12 EGO53723.1 - 0.097 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Translationally controlled tumour protein TPR_5 PF12688.2 EGO53723.1 - 0.098 12.7 0.1 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 Tetratrico peptide repeat SBDS PF01172.13 EGO53727.1 - 2.1e-27 94.7 0.3 2.4e-27 94.5 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.15 EGO53728.1 - 5.6e-21 75.2 0.0 2.7e-20 72.9 0.0 2.0 1 1 0 1 1 1 1 RhoGEF domain GRASP55_65 PF04495.9 EGO53730.1 - 2.7e-06 27.4 0.0 5.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EGO53730.1 - 4.8e-06 26.3 0.0 8.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EGO53730.1 - 3.8e-05 23.7 0.1 6.2e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Ras PF00071.17 EGO53731.1 - 2.7e-49 166.6 0.0 3.3e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO53731.1 - 1.5e-15 57.7 0.0 3e-15 56.7 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EGO53731.1 - 1.7e-10 40.4 0.0 2.2e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EGO53731.1 - 0.00067 19.8 0.1 0.004 17.3 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EGO53731.1 - 0.0019 17.3 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 EGO53731.1 - 0.024 13.9 0.1 0.041 13.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 EGO53731.1 - 0.055 12.1 2.6 1.1 7.8 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit AAA_33 PF13671.1 EGO53731.1 - 0.066 13.0 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGO53731.1 - 0.076 13.1 0.1 0.31 11.1 0.1 1.9 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.5 EGO53731.1 - 0.081 12.1 0.0 0.13 11.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit STAS PF01740.16 EGO53731.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 STAS domain KaiC PF06745.8 EGO53731.1 - 0.15 11.1 0.2 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 KaiC Septin PF00735.13 EGO53731.1 - 0.16 10.9 0.5 0.36 9.8 0.0 1.7 2 0 0 2 2 2 0 Septin WSC PF01822.14 EGO53732.1 - 3.4e-92 302.4 91.8 2.5e-19 68.9 10.2 5.3 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.6 EGO53732.1 - 1.1e-28 100.0 0.0 3.1e-27 95.2 0.0 2.9 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EGO53732.1 - 1.1e-20 73.4 0.0 2.3e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Macro_2 PF14519.1 EGO53732.1 - 0.23 10.5 0.1 1 8.3 0.0 2.0 2 0 0 2 2 2 0 Macro-like domain Aldedh PF00171.17 EGO53733.1 - 1.7e-133 445.3 0.3 2.1e-133 445.0 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGO53733.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Calreticulin PF00262.13 EGO53734.1 - 4.5e-161 535.5 16.4 6.8e-161 534.9 11.4 1.3 1 0 0 1 1 1 1 Calreticulin family Aldolase_II PF00596.16 EGO53735.1 - 3e-40 137.7 0.0 3.7e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain LcnG-beta PF11632.3 EGO53735.1 - 2.2 8.1 6.3 0.73 9.6 2.0 2.0 2 0 0 2 2 2 0 Lactococcin G-beta TIL PF01826.12 EGO53736.1 - 0.02 14.9 7.1 0.037 14.1 0.3 2.3 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain DUF326 PF03860.11 EGO53736.1 - 8 6.4 6.8 7.7 6.5 0.7 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF326) Fer4_3 PF12798.2 EGO53736.1 - 8.7 7.1 10.7 2.7 8.7 0.6 3.4 3 1 0 3 3 3 0 4Fe-4S binding domain adh_short PF00106.20 EGO53737.1 - 1.9e-20 73.4 0.2 5.8e-19 68.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO53737.1 - 9.4e-10 38.6 0.1 9.3e-09 35.3 0.1 2.2 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO53737.1 - 2.5e-09 37.0 0.0 3.6e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO53737.1 - 0.0015 18.0 0.1 0.0025 17.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EGO53737.1 - 0.033 13.3 0.0 0.072 12.2 0.0 1.4 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sld5 PF05916.6 EGO53738.1 - 2.5e-08 34.1 0.7 4.6e-08 33.3 0.5 1.5 1 0 0 1 1 1 1 GINS complex protein Menin PF05053.8 EGO53739.1 - 3 5.8 14.8 0.17 10.0 3.3 2.1 1 1 1 2 2 2 0 Menin SnoaL PF07366.7 EGO53740.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Pkinase PF00069.20 EGO53741.1 - 2e-66 223.8 0.0 2.8e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO53741.1 - 2.1e-40 138.4 0.0 3.1e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO53741.1 - 8.5e-09 34.7 0.0 1.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.13 EGO53741.1 - 8.9e-09 35.1 0.5 4.9e-06 26.4 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kdo PF06293.9 EGO53741.1 - 0.0027 16.8 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OPA3 PF07047.7 EGO53742.1 - 5.4e-38 129.7 1.3 8.1e-38 129.2 0.9 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Sugarporin_N PF11471.3 EGO53742.1 - 1.6 8.4 6.5 1.5 8.5 0.0 3.1 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Pacs-1 PF10254.4 EGO53743.1 - 0.23 10.0 4.1 0.24 10.0 2.8 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Senescence_reg PF04520.8 EGO53743.1 - 0.6 10.5 4.5 0.74 10.2 3.1 1.1 1 0 0 1 1 1 0 Senescence regulator TFIIF_alpha PF05793.7 EGO53743.1 - 0.61 8.3 6.1 0.66 8.2 4.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2360 PF10152.4 EGO53743.1 - 1 9.6 5.0 1.2 9.3 3.5 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Complex1_LYR PF05347.10 EGO53744.1 - 1.5e-08 34.2 0.3 3e-08 33.3 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGO53744.1 - 4.4e-07 29.9 0.2 7.5e-07 29.2 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EGO53744.1 - 5.1e-06 26.9 0.3 6.9e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like HA2 PF04408.18 EGO53745.1 - 1.5e-16 60.2 0.0 3e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGO53745.1 - 2.6e-14 52.9 0.1 6.9e-14 51.6 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGO53745.1 - 1.1e-12 47.5 0.0 2.8e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO53745.1 - 8.1e-08 31.9 0.1 4.8e-07 29.4 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGO53745.1 - 5.5e-05 23.3 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGO53745.1 - 0.013 14.9 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EGO53745.1 - 0.014 15.6 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 EGO53745.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein TRP PF06011.7 EGO53746.1 - 5.1e-133 443.8 19.3 6.9e-133 443.4 13.4 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGO53746.1 - 9e-39 132.7 3.2 1.5e-38 132.0 2.2 1.4 1 0 0 1 1 1 1 ML-like domain zf-C2H2 PF00096.21 EGO53747.1 - 1 9.8 27.6 0.41 11.0 0.2 5.2 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO53747.1 - 8 7.0 23.5 5.9 7.4 0.2 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger Tmemb_14 PF03647.8 EGO53748.1 - 2.8e-23 82.1 1.8 3e-23 82.0 1.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Cmc1 PF08583.5 EGO53749.1 - 6.8e-18 64.2 3.9 8.3e-18 63.9 2.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EGO53749.1 - 0.046 13.7 0.8 0.97 9.5 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 EGO53749.1 - 0.14 12.1 2.7 3.6 7.6 0.1 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Prefoldin_2 PF01920.15 EGO53750.1 - 1.5e-26 92.2 7.1 1.6e-26 92.1 4.9 1.0 1 0 0 1 1 1 1 Prefoldin subunit Taxilin PF09728.4 EGO53750.1 - 0.0014 17.7 2.7 0.39 9.7 0.8 2.0 2 0 0 2 2 2 2 Myosin-like coiled-coil protein Prefoldin PF02996.12 EGO53750.1 - 0.01 15.5 4.7 0.074 12.6 0.3 2.2 1 1 1 2 2 2 0 Prefoldin subunit DUF2205 PF10224.4 EGO53750.1 - 0.016 14.7 6.2 0.54 9.8 0.1 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) UBN2 PF14223.1 EGO53750.1 - 0.016 14.9 0.5 0.22 11.3 0.0 2.1 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type DUF2089 PF09862.4 EGO53750.1 - 0.024 14.4 0.6 0.089 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) TPR_MLP1_2 PF07926.7 EGO53750.1 - 0.049 13.3 4.3 0.22 11.2 0.4 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Dynactin PF12455.3 EGO53750.1 - 0.049 12.5 2.2 1.3 7.8 0.1 2.1 2 0 0 2 2 2 0 Dynein associated protein DUF641 PF04859.7 EGO53750.1 - 0.06 13.0 1.4 0.11 12.3 0.6 1.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF512 PF04459.7 EGO53750.1 - 0.071 12.1 0.1 0.1 11.6 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF512) Tho2 PF11262.3 EGO53750.1 - 0.073 12.1 1.6 0.91 8.5 0.1 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 IncA PF04156.9 EGO53750.1 - 0.13 11.8 1.7 0.17 11.4 1.2 1.2 1 0 0 1 1 1 0 IncA protein FKBP_N PF01346.13 EGO53750.1 - 0.13 12.2 3.3 1.4 8.9 0.1 2.1 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase THOC7 PF05615.8 EGO53750.1 - 0.19 12.0 3.3 1.3 9.2 0.6 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 BLOC1_2 PF10046.4 EGO53750.1 - 0.2 11.7 3.9 5 7.3 0.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin_2 PF14523.1 EGO53750.1 - 0.21 11.6 4.4 0.95 9.5 3.0 1.8 1 1 0 1 1 1 0 Syntaxin-like protein DUF148 PF02520.12 EGO53750.1 - 0.23 11.2 5.0 0.26 11.0 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF148 FliJ PF02050.11 EGO53750.1 - 0.41 10.7 5.9 2.9 7.9 0.7 2.0 2 0 0 2 2 2 0 Flagellar FliJ protein DUF3166 PF11365.3 EGO53750.1 - 0.9 10.0 3.9 12 6.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) YtxH PF12732.2 EGO53750.1 - 1.5 9.2 4.0 22 5.4 2.8 2.0 1 1 0 1 1 1 0 YtxH-like protein CBFD_NFYB_HMF PF00808.18 EGO53752.1 - 1e-29 102.3 1.0 1.3e-29 101.9 0.7 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGO53752.1 - 2.9e-07 30.4 0.1 4.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EGO53752.1 - 0.00074 19.2 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EGO53752.1 - 0.00098 18.8 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated Tmemb_cc2 PF10267.4 EGO53752.1 - 0.014 14.0 1.3 0.018 13.6 0.9 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein TFIID_20kDa PF03847.8 EGO53752.1 - 0.037 14.3 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A RRN3 PF05327.6 EGO53753.1 - 3.2e-167 557.0 0.7 3.2e-167 557.0 0.5 1.9 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Mg-por_mtran_C PF07109.6 EGO53753.1 - 0.09 12.8 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Magnesium-protoporphyrin IX methyltransferase C-terminus bZIP_1 PF00170.16 EGO53754.1 - 2.2e-06 27.4 0.7 4.1e-06 26.6 0.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EGO53754.1 - 0.00088 19.5 2.4 0.0018 18.5 1.6 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor CCDC-167 PF15188.1 EGO53754.1 - 0.046 13.6 0.6 0.077 12.9 0.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 TATR PF03430.8 EGO53754.1 - 2.3 6.7 11.8 3.1 6.3 8.2 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Patatin PF01734.17 EGO53756.1 - 6.1e-08 32.8 0.0 1.5e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.17 EGO53757.1 - 2.8e-23 82.9 0.0 6.1e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.17 EGO53757.1 - 2.8e-10 39.5 0.0 6e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 EGO53757.1 - 5.3e-05 23.0 7.9 0.017 15.0 0.5 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_5 PF07728.9 EGO53757.1 - 0.035 13.8 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EGO53757.1 - 0.04 13.0 0.0 7.1 5.6 0.0 2.8 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.1 EGO53757.1 - 0.09 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_7 PF13176.1 EGO53757.1 - 0.16 11.8 1.6 19 5.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGO53757.1 - 0.56 10.9 3.6 67 4.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SNARE PF05739.14 EGO53758.1 - 0.13 11.9 12.2 1.8 8.3 0.3 3.6 2 1 2 4 4 4 0 SNARE domain GTP_EFTU PF00009.22 EGO53760.1 - 7e-07 28.8 0.0 1.6e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EGO53760.1 - 0.025 14.0 1.0 0.09 12.3 0.3 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EGO53760.1 - 0.078 13.2 0.3 0.57 10.4 0.1 2.3 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 EGO53760.1 - 0.11 11.3 0.1 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Rab5ip PF07019.7 EGO53761.1 - 5.8e-13 48.7 0.7 8.3e-13 48.2 0.5 1.3 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Vezatin PF12632.2 EGO53762.1 - 2.9e-61 206.7 0.0 7e-61 205.4 0.0 1.6 1 1 0 1 1 1 1 Mysoin-binding motif of peroxisomes GtrA PF04138.9 EGO53762.1 - 0.14 12.1 4.8 0.071 13.0 1.8 1.6 2 0 0 2 2 2 0 GtrA-like protein IncA PF04156.9 EGO53762.1 - 0.2 11.2 10.7 0.11 12.1 0.1 2.7 3 0 0 3 3 3 0 IncA protein DUF4381 PF14316.1 EGO53762.1 - 0.89 9.6 3.3 5.7 7.0 2.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) PCNA_N PF00705.13 EGO53763.1 - 2.4e-55 185.4 5.8 4e-55 184.7 3.1 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EGO53763.1 - 1.2e-52 177.1 0.6 5.5e-52 175.0 0.1 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EGO53763.1 - 3.4e-10 39.4 0.4 4.1e-10 39.2 0.3 1.2 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EGO53763.1 - 1.5e-05 24.0 0.7 0.0011 17.9 0.1 2.1 2 0 0 2 2 2 2 Hus1-like protein RR_TM4-6 PF06459.7 EGO53764.1 - 0.74 9.6 7.3 1.2 8.9 5.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 dUTPase PF00692.14 EGO53765.1 - 2.6e-43 146.5 0.0 3e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 dUTPase DCD PF06559.6 EGO53765.1 - 0.0082 14.5 0.1 0.01 14.2 0.0 1.1 1 0 0 1 1 1 1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) CENP-K PF11802.3 EGO53766.1 - 5e-13 48.8 0.2 1.5e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 Centromere-associated protein K Noc2 PF03715.8 EGO53766.1 - 0.068 12.0 0.1 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Noc2p family AAA_13 PF13166.1 EGO53766.1 - 0.12 10.7 4.8 0.16 10.3 2.3 1.8 2 0 0 2 2 2 0 AAA domain Mlp PF03304.8 EGO53766.1 - 0.27 11.2 5.9 0.057 13.4 1.0 2.0 2 0 0 2 2 2 0 Mlp lipoprotein family Fib_alpha PF08702.5 EGO53766.1 - 1 9.4 6.2 6.5 6.8 0.0 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4404 PF14357.1 EGO53766.1 - 1.4 9.3 14.9 10 6.6 6.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) DUF342 PF03961.8 EGO53766.1 - 2.9 6.2 13.6 0.15 10.4 3.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF342) SlyX PF04102.7 EGO53766.1 - 4.1 7.8 11.5 24 5.3 3.5 3.2 3 1 0 3 3 3 0 SlyX IncA PF04156.9 EGO53766.1 - 8.3 5.9 18.4 0.053 13.1 5.3 2.3 3 0 0 3 3 3 0 IncA protein KH_1 PF00013.24 EGO53767.1 - 1.6e-41 139.7 5.8 1.9e-16 59.4 0.5 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EGO53767.1 - 5.3e-31 105.7 12.9 2.6e-11 42.8 2.8 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EGO53767.1 - 8.5e-13 47.6 4.2 0.0027 17.2 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EGO53767.1 - 4.1e-05 23.1 0.5 0.91 9.2 0.1 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EGO53767.1 - 0.0014 18.3 6.0 0.79 9.5 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain PAPS_reduct PF01507.14 EGO53770.1 - 5e-29 101.3 0.0 1.4e-20 73.8 0.0 2.3 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family IBR PF01485.16 EGO53772.1 - 3.8e-08 33.0 29.0 2.4e-06 27.3 5.0 3.8 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EGO53772.1 - 0.00068 19.4 1.0 0.00068 19.4 0.7 3.5 3 0 0 3 3 3 2 Ring finger domain DUF3330 PF11809.3 EGO53772.1 - 0.00089 19.0 0.3 0.0037 17.1 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3330) zf-C3HC4_2 PF13923.1 EGO53772.1 - 0.016 15.2 1.6 0.016 15.2 1.1 4.0 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF853 PF05872.7 EGO53772.1 - 0.1 10.9 0.4 0.15 10.4 0.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DRY_EERY PF09750.4 EGO53772.1 - 5.8 7.0 17.9 0.31 11.1 5.8 2.7 3 0 0 3 3 3 0 Alternative splicing regulator DUF1275 PF06912.6 EGO53773.1 - 2.2e-45 154.4 13.5 2.8e-45 154.0 9.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Cys_Met_Meta_PP PF01053.15 EGO53774.1 - 3.2e-136 453.6 0.3 3.6e-136 453.4 0.2 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EGO53774.1 - 9.4e-07 28.1 0.2 1.5e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGO53774.1 - 2.7e-06 26.4 0.4 5.1e-06 25.4 0.3 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGO53774.1 - 7e-05 22.0 0.4 0.00013 21.1 0.3 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Zn_clus PF00172.13 EGO53776.1 - 3.2e-08 33.3 10.3 5.4e-08 32.6 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGO53776.1 - 1.4e-05 23.8 0.7 2.7e-05 22.9 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Brix PF04427.13 EGO53777.1 - 3.4e-37 127.9 0.3 5.4e-37 127.3 0.2 1.3 1 0 0 1 1 1 1 Brix domain EURL PF06937.6 EGO53777.1 - 0.037 13.4 0.1 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 EURL protein RICTOR_N PF14664.1 EGO53778.1 - 0.1 11.1 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term DUF1765 PF08578.5 EGO53779.1 - 2.1e-50 170.0 5.9 3.4e-50 169.3 4.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) DEAD PF00270.24 EGO53780.1 - 4.1e-20 71.9 0.0 4.1e-20 71.9 0.0 3.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO53780.1 - 1.5e-16 59.9 0.1 1.5e-16 59.9 0.0 3.5 3 1 0 3 3 3 1 Helicase conserved C-terminal domain HRDC PF00570.18 EGO53780.1 - 4.1e-05 23.2 0.0 0.00015 21.3 0.0 2.0 1 0 0 1 1 1 1 HRDC domain Mem_trans PF03547.13 EGO53780.1 - 0.86 7.8 11.4 0.72 8.0 5.6 2.3 2 0 0 2 2 2 0 Membrane transport protein KAR9 PF08580.5 EGO53783.1 - 1.2e-194 648.4 0.1 1.2e-194 648.4 0.1 3.9 2 2 0 3 3 3 1 Yeast cortical protein KAR9 Yip1 PF04893.12 EGO53785.1 - 0.00012 21.5 0.2 0.00014 21.4 0.1 1.0 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EGO53785.1 - 0.016 14.8 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Sdh_cyt PF01127.17 EGO53785.1 - 0.035 13.9 0.0 0.047 13.5 0.0 1.1 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4131 PF13567.1 EGO53785.1 - 0.074 12.4 0.3 0.085 12.2 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4064 PF13273.1 EGO53785.1 - 0.083 13.0 0.4 0.7 10.0 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF1469 PF07332.6 EGO53785.1 - 0.23 11.1 2.0 10 5.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Daxx PF03344.10 EGO53787.1 - 0.00065 18.3 23.3 0.00065 18.3 16.2 2.3 2 0 0 2 2 2 1 Daxx Family Ycf1 PF05758.7 EGO53787.1 - 0.22 9.1 10.2 0.43 8.2 7.1 1.3 1 0 0 1 1 1 0 Ycf1 Pox_Ag35 PF03286.9 EGO53787.1 - 4.3 6.8 22.2 15 5.0 15.4 1.9 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Proteasome PF00227.21 EGO53788.1 - 7.3e-46 155.8 0.0 9.4e-46 155.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EGO53788.1 - 9.2e-15 53.6 0.6 1.9e-14 52.6 0.4 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Sel1 PF08238.7 EGO53789.1 - 4.8e-13 49.2 13.6 0.0015 19.0 0.1 4.5 4 0 0 4 4 4 3 Sel1 repeat DUF1571 PF07608.6 EGO53789.1 - 0.15 11.2 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) COPIIcoated_ERV PF07970.7 EGO53790.1 - 6.3e-70 235.2 0.0 1.8e-46 158.5 0.0 2.3 1 1 1 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EGO53790.1 - 1.5e-35 121.0 0.0 2.8e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Per1 PF04080.8 EGO53792.1 - 2.1e-103 345.4 6.4 2.9e-103 344.9 4.4 1.1 1 0 0 1 1 1 1 Per1-like Serglycin PF04360.7 EGO53793.1 - 0.11 12.2 0.9 0.22 11.2 0.6 1.4 1 0 0 1 1 1 0 Serglycin Ppx-GppA PF02541.11 EGO53794.1 - 5.4e-29 101.2 0.0 8.7e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Tyrosinase PF00264.15 EGO53798.1 - 2.3e-55 188.1 0.7 3.2e-55 187.7 0.5 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase RNA_pol_Rpb2_6 PF00562.23 EGO53799.1 - 1e-113 380.0 0.1 1.3e-113 379.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGO53799.1 - 1.1e-30 106.1 0.0 1.6e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpa2_4 PF06883.7 EGO53799.1 - 1e-25 89.4 0.0 2.3e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 EGO53799.1 - 1.7e-25 89.5 0.0 4e-25 88.3 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EGO53799.1 - 3.1e-25 87.7 0.0 7e-25 86.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 EGO53799.1 - 2.8e-14 53.1 0.0 1.7e-13 50.6 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EGO53799.1 - 0.00012 22.0 0.0 0.00027 20.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Arf PF00025.16 EGO53800.1 - 5.6e-43 146.1 0.0 6.6e-43 145.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGO53800.1 - 2.6e-19 69.1 0.0 3e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO53800.1 - 1.5e-10 41.6 0.0 2.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EGO53800.1 - 1.8e-07 30.5 0.0 2.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGO53800.1 - 4.8e-07 29.1 0.0 5.9e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGO53800.1 - 1.4e-05 23.9 0.1 3.9e-05 22.5 0.0 1.7 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EGO53800.1 - 3.7e-05 23.6 0.0 5.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO53800.1 - 5.4e-05 22.6 0.0 0.0007 19.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EGO53800.1 - 0.079 12.7 0.1 0.37 10.6 0.1 1.8 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.13 EGO53800.1 - 0.086 12.1 0.1 0.43 9.8 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF1979 PF09322.5 EGO53800.1 - 0.1 12.2 0.3 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) PduV-EutP PF10662.4 EGO53800.1 - 0.16 11.4 0.0 0.5 9.8 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_S9 PF00380.14 EGO53801.1 - 1.5e-37 128.5 0.3 1.7e-37 128.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 RCR PF12273.3 EGO53802.1 - 1.6e-24 86.9 7.7 2.1e-24 86.5 5.3 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red HAMP PF00672.20 EGO53802.1 - 0.067 13.3 0.6 12 6.1 0.5 2.1 2 0 0 2 2 2 0 HAMP domain WBP-1 PF11669.3 EGO53802.1 - 5.4 7.1 11.5 0.063 13.3 1.8 2.1 1 1 1 2 2 2 0 WW domain-binding protein 1 UDPGT PF00201.13 EGO53806.1 - 3.5e-07 29.1 0.0 4.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EGO53806.1 - 0.00053 19.6 0.0 0.00086 18.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.15 EGO53806.1 - 0.002 17.8 0.0 0.0054 16.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Tox-HNH-HHH PF15637.1 EGO53806.1 - 0.077 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif FAD_binding_7 PF03441.9 EGO53807.1 - 2.9e-97 325.2 0.0 5.5e-97 324.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EGO53807.1 - 6.7e-37 126.7 0.0 1.7e-36 125.4 0.0 1.6 2 0 0 2 2 2 1 DNA photolyase Ribosomal_S21e PF01249.13 EGO53808.1 - 3.8e-38 129.2 0.1 4.2e-38 129.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Slx4 PF09494.5 EGO53809.1 - 2.8e-19 68.6 0.0 5.2e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease WD40 PF00400.27 EGO53813.1 - 1.5e-18 65.8 9.2 3.4e-09 36.2 1.5 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EGO53813.1 - 0.022 14.4 0.0 0.057 13.1 0.0 1.7 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A PHD PF00628.24 EGO53813.1 - 7.1 6.4 9.7 9.6 5.9 0.3 2.9 2 1 1 3 3 3 0 PHD-finger Cactin_mid PF10312.4 EGO53814.1 - 4.3e-66 221.8 7.1 5.8e-66 221.4 5.0 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EGO53814.1 - 2.5e-55 185.4 3.8 4.1e-55 184.7 2.6 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF1087 PF06465.8 EGO53814.1 - 0.031 14.1 5.2 0.19 11.6 0.3 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) CCER1 PF15482.1 EGO53815.1 - 0.096 12.3 1.2 0.1 12.2 0.8 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Fork_head PF00250.13 EGO53816.1 - 2.6e-17 62.6 0.9 2.6e-17 62.6 0.6 2.0 2 0 0 2 2 1 1 Fork head domain RR_TM4-6 PF06459.7 EGO53816.1 - 0.33 10.8 12.6 0.03 14.2 4.3 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4199 PF13858.1 EGO53816.1 - 1 9.2 7.8 1.8 8.4 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) RasGEF_N PF00618.15 EGO53816.1 - 1.3 9.1 3.9 24 5.1 0.1 2.5 2 0 0 2 2 2 0 RasGEF N-terminal motif OATP PF03137.15 EGO53816.1 - 1.9 6.4 5.8 3.8 5.4 4.1 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF853 PF05872.7 EGO53816.1 - 2 6.6 6.6 3.4 5.9 4.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF3533 PF12051.3 EGO53816.1 - 2.2 6.9 7.0 3.6 6.2 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) FimP PF09766.4 EGO53816.1 - 3.4 6.6 26.5 0.33 9.9 13.3 2.1 2 0 0 2 2 2 0 Fms-interacting protein FYDLN_acid PF09538.5 EGO53816.1 - 5.8 7.5 9.8 0.5 10.9 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DnaJ-X PF14308.1 EGO53816.1 - 6.9 5.8 17.3 0.68 9.1 0.8 2.3 2 0 0 2 2 2 0 X-domain of DnaJ-containing DUF3449 PF11931.3 EGO53816.1 - 8 5.9 18.8 1.3 8.4 4.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) Peptidase_C74 PF12387.3 EGO53817.1 - 0.12 11.5 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 Pestivirus NS2 peptidase XLF PF09302.6 EGO53819.1 - 1.9e-40 138.4 0.0 2.7e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 XLF (XRCC4-like factor) AAA PF00004.24 EGO53823.1 - 7.9e-16 58.4 0.0 1.7e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGO53823.1 - 1.9e-05 24.7 0.0 0.00021 21.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGO53823.1 - 7.4e-05 22.9 1.7 0.021 14.9 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 EGO53823.1 - 0.0015 18.2 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EGO53823.1 - 0.0081 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EGO53823.1 - 0.025 14.3 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EGO53823.1 - 0.032 15.0 4.6 0.18 12.6 0.0 3.2 3 1 0 3 3 3 0 AAA domain cNMP_binding PF00027.24 EGO53824.1 - 3.8e-36 122.7 0.0 2.2e-18 65.8 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EGO53824.1 - 6.6e-16 56.5 6.5 0.11 12.6 0.1 7.8 8 0 0 8 8 8 5 Leucine Rich repeat F-box PF00646.28 EGO53824.1 - 1.1e-08 34.5 3.8 1.1e-08 34.5 2.7 2.9 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EGO53824.1 - 8.6e-08 31.7 3.3 8.6e-08 31.7 2.3 2.3 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EGO53824.1 - 1.2e-06 28.2 1.0 0.018 14.7 0.0 3.8 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EGO53824.1 - 3.4e-06 26.3 6.1 8.4 6.8 0.0 7.5 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.2 EGO53824.1 - 2.7e-05 23.6 0.4 0.27 10.9 0.1 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EGO53824.1 - 0.0034 17.3 10.3 32 5.3 0.1 6.8 6 0 0 6 6 6 0 Leucine rich repeat Cupin_3 PF05899.7 EGO53824.1 - 0.048 13.0 0.1 3.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DUF3433 PF11915.3 EGO53826.1 - 6.3e-25 87.1 0.5 6.3e-25 87.1 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) Kelch_5 PF13854.1 EGO53826.1 - 2.3e-12 46.5 0.4 8.6e-11 41.5 0.1 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 EGO53826.1 - 0.0023 17.6 4.0 0.007 16.1 0.1 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.1 EGO53826.1 - 0.004 17.2 5.4 0.017 15.2 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 EGO53826.1 - 0.0059 16.7 1.6 0.22 11.7 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Bax1-I PF01027.15 EGO53827.1 - 2.5e-32 112.1 12.1 3.3e-32 111.7 8.4 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Rox3 PF08633.5 EGO53831.1 - 4.1e-66 222.9 0.1 4.1e-66 222.9 0.1 2.2 2 1 0 2 2 2 1 Rox3 mediator complex subunit MIR PF02815.14 EGO53831.1 - 0.011 15.2 0.2 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 MIR domain Herpes_UL56 PF04534.7 EGO53833.1 - 0.035 13.8 0.7 0.04 13.6 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein GRP PF07172.6 EGO53834.1 - 0.064 13.7 12.7 0.063 13.7 8.8 1.2 1 0 0 1 1 1 0 Glycine rich protein family RRM_5 PF13893.1 EGO53834.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_6 PF12697.2 EGO53840.1 - 4.1e-13 49.7 0.1 5e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO53840.1 - 5.4e-07 29.4 0.5 8.3e-07 28.8 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO53840.1 - 0.00065 19.4 0.1 0.0059 16.4 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Lipase_3 PF01764.20 EGO53840.1 - 0.017 14.7 0.1 0.026 14.1 0.1 1.5 1 1 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EGO53840.1 - 0.099 12.2 0.4 0.25 10.8 0.2 1.6 2 0 0 2 2 2 0 PGAP1-like protein DUF2974 PF11187.3 EGO53840.1 - 0.13 11.5 0.1 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DBR1 PF05011.8 EGO53841.1 - 2.3e-46 157.3 0.0 4e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EGO53841.1 - 9.9e-08 31.6 1.4 9.9e-08 31.6 1.0 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase MatE PF01554.13 EGO53844.1 - 4.9e-51 172.5 18.2 2.8e-29 101.8 2.7 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EGO53844.1 - 3.1e-06 27.0 4.1 3.1e-06 27.0 2.8 4.2 2 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF679 PF05078.7 EGO53844.1 - 0.15 11.6 1.6 2.2 7.9 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF679) Dispanin PF04505.7 EGO53844.1 - 0.23 11.0 4.6 0.19 11.2 1.2 2.3 2 0 0 2 2 2 0 Interferon-induced transmembrane protein UPF0052 PF01933.13 EGO53845.1 - 5.4e-36 124.4 0.0 1e-34 120.2 0.0 2.0 2 0 0 2 2 2 2 Uncharacterised protein family UPF0052 Alpha_kinase PF02816.13 EGO53846.1 - 3.1e-48 163.9 0.0 4.6e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.1 EGO53846.1 - 1e-06 28.9 0.0 2.3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EGO53846.1 - 0.0007 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Pkinase PF00069.20 EGO53849.1 - 2.4e-41 141.6 0.2 2.4e-25 89.2 0.1 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO53849.1 - 1.4e-14 53.8 0.3 4.9e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Na_trans_assoc PF06512.8 EGO53850.1 - 0.02 14.8 9.0 0.025 14.5 6.3 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Pox_Ag35 PF03286.9 EGO53850.1 - 0.35 10.3 10.2 0.54 9.7 6.9 1.5 1 1 0 1 1 1 0 Pox virus Ag35 surface protein DUF1675 PF07897.6 EGO53850.1 - 0.75 9.6 8.6 1.1 9.1 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Macoilin PF09726.4 EGO53850.1 - 2 6.5 9.3 2.4 6.3 6.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Dicty_REP PF05086.7 EGO53850.1 - 2.3 5.8 8.4 2.9 5.5 5.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ARS2 PF04959.8 EGO53850.1 - 7.9 6.6 9.8 0.4 10.8 2.5 1.8 2 0 0 2 2 2 0 Arsenite-resistance protein 2 Utp14 PF04615.8 EGO53850.1 - 7.9 4.4 16.6 9.8 4.2 11.5 1.0 1 0 0 1 1 1 0 Utp14 protein RabGAP-TBC PF00566.13 EGO53851.1 - 2.3e-42 144.9 0.0 1.2e-41 142.6 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain B3_4 PF03483.12 EGO53853.1 - 4.7e-26 91.3 0.0 7.6e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EGO53853.1 - 2.9e-16 59.0 0.0 1.1e-13 50.8 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 EGO53853.1 - 0.051 12.6 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein tRNA-synt_1b PF00579.20 EGO53856.1 - 2.5e-20 72.7 0.4 5.2e-20 71.7 0.0 1.7 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) 2CSK_N PF08521.5 EGO53856.1 - 0.0038 16.7 0.1 0.0062 16.0 0.1 1.3 1 0 0 1 1 1 1 Two-component sensor kinase N-terminal DUF3435 PF11917.3 EGO53857.1 - 3.3e-15 55.7 0.1 4.2e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Defensin_1 PF00323.14 EGO53857.1 - 0.055 13.8 2.0 0.14 12.5 1.4 1.7 1 0 0 1 1 1 0 Mammalian defensin zf-CCHC PF00098.18 EGO53858.1 - 6.9e-06 25.7 3.1 1.5e-05 24.6 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EGO53858.1 - 0.00086 18.7 0.1 0.0016 17.8 0.1 1.4 1 0 0 1 1 1 1 Zinc knuckle PLU-1 PF08429.6 EGO53858.1 - 0.025 13.4 0.1 0.035 13.0 0.1 1.2 1 0 0 1 1 1 0 PLU-1-like protein Vfa1 PF08432.5 EGO53858.1 - 0.06 13.3 5.5 0.09 12.7 3.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SR-25 PF10500.4 EGO53858.1 - 1.2 8.6 16.3 1.4 8.3 11.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PARP PF00644.15 EGO53860.1 - 7.1e-66 221.5 0.0 1.2e-65 220.8 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EGO53860.1 - 1.5e-42 144.3 0.7 2.3e-42 143.8 0.5 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EGO53860.1 - 5.1e-13 48.7 0.1 1.6e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 WGR domain Flu_NS2 PF00601.14 EGO53861.1 - 1.1 9.4 5.0 7.2 6.8 1.6 3.2 1 1 2 3 3 3 0 Influenza non-structural protein (NS2) DUF2935 PF11155.3 EGO53861.1 - 1.2 9.2 12.5 1.8 8.6 2.3 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) Tropomyosin PF00261.15 EGO53862.1 - 0.043 12.9 10.1 0.29 10.1 0.3 3.5 2 1 0 2 2 2 0 Tropomyosin IncA PF04156.9 EGO53862.1 - 0.052 13.1 8.1 4.2 6.9 0.0 3.2 3 1 0 3 3 3 0 IncA protein Uds1 PF15456.1 EGO53862.1 - 0.054 13.4 3.6 0.082 12.9 0.9 2.5 2 1 0 3 3 3 0 Up-regulated During Septation AAA_13 PF13166.1 EGO53862.1 - 0.12 10.8 7.3 0.19 10.1 2.8 2.1 2 0 0 2 2 2 0 AAA domain COG2 PF06148.6 EGO53862.1 - 0.22 11.3 5.3 3.1 7.6 0.2 3.4 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.6 EGO53862.1 - 0.3 11.4 7.4 1.9 8.9 0.9 3.6 3 1 0 3 3 3 0 Syntaxin 6, N-terminal YgaB PF14182.1 EGO53862.1 - 0.4 10.9 4.9 0.79 9.9 0.3 3.2 3 1 0 3 3 3 0 YgaB-like protein Mnd1 PF03962.10 EGO53862.1 - 0.43 10.2 6.5 5.7 6.5 0.0 3.5 2 1 1 3 3 3 0 Mnd1 family CCDC144C PF14915.1 EGO53862.1 - 0.47 9.3 10.8 1 8.1 0.0 3.1 3 1 0 3 3 3 0 CCDC144C protein coiled-coil region Fib_alpha PF08702.5 EGO53862.1 - 0.49 10.5 10.4 0.35 10.9 3.1 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family WEMBL PF05701.6 EGO53862.1 - 0.62 8.4 14.4 38 2.5 10.0 2.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light FlaC_arch PF05377.6 EGO53862.1 - 1.1 9.1 6.9 5.6 6.9 0.7 3.1 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) ATP-synt_B PF00430.13 EGO53862.1 - 1.6 8.5 11.3 0.7 9.6 1.6 2.7 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Spc7 PF08317.6 EGO53862.1 - 2.4 6.7 12.0 0.67 8.5 3.7 2.5 3 0 0 3 3 3 0 Spc7 kinetochore protein NPV_P10 PF05531.7 EGO53862.1 - 3.1 8.1 13.3 19 5.5 0.1 4.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.2 EGO53862.1 - 3.3 6.9 20.9 1.2 8.4 2.1 3.2 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 EGO53862.1 - 4.4 6.4 7.9 0.86 8.7 1.6 2.3 2 1 0 3 3 3 0 Reovirus sigma C capsid protein PAN_4 PF14295.1 EGO53865.1 - 0.00063 19.3 2.4 0.0012 18.4 1.6 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EGO53865.1 - 0.0053 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 EGO53865.1 - 0.006 16.1 0.4 0.013 15.0 0.3 1.5 1 0 0 1 1 1 1 PAN-like domain Shisa PF13908.1 EGO53865.1 - 0.027 14.6 0.0 0.027 14.6 0.0 3.0 2 2 1 3 3 3 0 Wnt and FGF inhibitory regulator Sporozoite_P67 PF05642.6 EGO53865.1 - 0.077 10.8 3.5 0.098 10.5 2.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YjbE PF11106.3 EGO53865.1 - 5.2 7.0 14.5 6.6 6.7 6.5 2.7 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE ABC2_membrane PF01061.19 EGO53866.1 - 1.8e-22 79.5 26.9 2.7e-22 79.0 18.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EGO53866.1 - 6.5e-14 52.3 0.0 1.2e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EGO53866.1 - 1.9e-05 24.7 0.1 7.3e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EGO53866.1 - 0.0023 17.1 0.1 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGO53866.1 - 0.0044 17.1 0.0 0.009 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO53866.1 - 0.017 15.9 0.4 0.044 14.6 0.3 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EGO53866.1 - 0.021 14.8 0.1 0.098 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain PDR_CDR PF06422.7 EGO53866.1 - 0.053 13.1 0.0 0.053 13.1 0.0 2.4 2 1 1 3 3 3 0 CDR ABC transporter AAA_24 PF13479.1 EGO53866.1 - 0.082 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGO53866.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 EGO53866.1 - 0.1 12.8 0.2 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGO53866.1 - 0.13 12.1 0.2 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain MtrG PF04210.8 EGO53866.1 - 0.13 11.9 0.4 0.37 10.4 0.3 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G SIR2 PF02146.12 EGO53867.1 - 1.2e-59 200.9 0.0 3.5e-59 199.5 0.0 1.8 1 1 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EGO53867.1 - 1.7e-05 24.4 0.1 4.1e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF592) DUF2201_N PF13203.1 EGO53867.1 - 0.0033 16.6 1.2 0.0033 16.6 0.8 2.8 3 1 1 4 4 4 1 Putative metallopeptidase domain TPP_enzyme_M PF00205.17 EGO53867.1 - 0.01 15.5 0.1 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain TAT_signal PF10518.4 EGO53867.1 - 0.11 12.5 2.2 0.24 11.5 1.6 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence AMP-binding PF00501.23 EGO53869.1 - 5.6e-78 262.1 0.0 7.6e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO53869.1 - 6.3e-12 46.2 1.2 5.3e-11 43.2 0.2 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AhpC-TSA PF00578.16 EGO53871.1 - 1.2e-31 109.0 0.0 1.5e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EGO53871.1 - 1.9e-11 43.4 0.0 3.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EGO53871.1 - 6.9e-11 41.8 0.0 8.9e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin Vac7 PF12751.2 EGO53872.1 - 2.3e-87 293.3 47.3 1e-57 195.7 12.9 4.0 2 1 2 4 4 4 3 Vacuolar segregation subunit 7 PTCB-BRCT PF12738.2 EGO53873.1 - 0.00018 21.2 1.2 0.00072 19.3 0.0 2.5 3 0 0 3 3 3 1 twin BRCT domain BRCT PF00533.21 EGO53873.1 - 0.00026 21.0 0.0 0.00059 19.9 0.0 1.6 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PBP PF01161.15 EGO53874.1 - 7.7e-15 55.0 0.0 1.3e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF2064 PF09837.4 EGO53874.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) Ribosomal_L4 PF00573.17 EGO53875.1 - 3.7e-42 143.8 0.0 6.3e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Glyco_transf_34 PF05637.7 EGO53877.1 - 8.5e-15 54.9 0.0 6.5e-12 45.4 0.0 2.5 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EGO53877.1 - 0.0012 18.1 0.1 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF273 Zip PF02535.17 EGO53877.1 - 1.1 8.1 6.9 2.2 7.1 2.1 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter DDHD PF02862.12 EGO53877.1 - 2.1 8.0 14.7 0.43 10.3 7.6 1.7 2 0 0 2 2 2 0 DDHD domain Vfa1 PF08432.5 EGO53877.1 - 9.4 6.2 25.4 18 5.2 17.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sld5 PF05916.6 EGO53879.1 - 9.6e-15 54.8 0.0 1.9e-14 53.8 0.0 1.5 1 1 0 1 1 1 1 GINS complex protein Sod_Fe_C PF02777.13 EGO53880.1 - 8.6e-39 131.6 0.3 1.5e-38 130.8 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EGO53880.1 - 7.5e-31 106.2 0.6 3.1e-30 104.2 0.6 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain PRP1_N PF06424.7 EGO53881.1 - 4.2e-49 166.2 6.3 4.2e-49 166.2 4.4 2.0 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EGO53881.1 - 1.3e-33 112.3 39.1 0.00088 19.7 0.0 14.4 5 3 9 14 14 14 11 Tetratricopeptide repeat TPR_19 PF14559.1 EGO53881.1 - 2.9e-27 94.7 26.5 4.9e-06 26.7 0.1 9.1 8 1 1 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 EGO53881.1 - 7.1e-22 77.5 26.7 3.5e-05 24.3 0.0 8.8 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 EGO53881.1 - 9.6e-16 56.3 15.8 0.066 13.1 0.0 12.3 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGO53881.1 - 1.1e-14 53.8 17.8 7.9e-06 25.4 0.0 9.1 6 3 5 11 11 11 4 TPR repeat TPR_12 PF13424.1 EGO53881.1 - 1.3e-11 44.2 5.1 0.052 13.4 0.0 7.6 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGO53881.1 - 4e-09 35.5 4.5 0.29 11.0 0.0 9.0 9 1 1 10 10 10 1 Tetratricopeptide repeat Suf PF05843.9 EGO53881.1 - 4e-08 33.3 0.9 0.62 9.7 0.0 5.0 5 0 0 5 5 5 3 Suppressor of forked protein (Suf) TPR_9 PF13371.1 EGO53881.1 - 1.4e-07 31.3 13.4 0.00052 19.8 0.0 6.6 6 2 1 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO53881.1 - 2.4e-07 30.3 4.3 0.29 11.4 0.0 8.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGO53881.1 - 5.5e-07 28.9 0.1 0.85 9.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 EGO53881.1 - 7.3e-07 28.5 22.1 0.0025 16.9 1.3 5.9 2 2 1 5 5 5 3 Tetratricopeptide repeat NARP1 PF12569.3 EGO53881.1 - 4.2e-06 25.8 11.9 0.071 11.8 0.0 5.9 4 1 3 7 7 7 2 NMDA receptor-regulated protein 1 ChAPs PF09295.5 EGO53881.1 - 0.0018 17.1 8.1 0.022 13.5 0.0 3.8 3 1 1 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.1 EGO53881.1 - 0.0039 17.5 23.2 15 6.2 0.0 10.5 12 0 0 12 12 10 0 Tetratricopeptide repeat DUF3808 PF10300.4 EGO53881.1 - 0.0046 15.5 4.3 2.4 6.6 0.0 4.6 2 1 2 4 4 4 1 Protein of unknown function (DUF3808) TPR_7 PF13176.1 EGO53881.1 - 0.011 15.4 0.7 27 4.8 0.1 4.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Spt5_N PF11942.3 EGO53881.1 - 0.34 11.5 11.3 2 9.0 7.9 2.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF3176 PF11374.3 EGO53882.1 - 7.5e-09 35.4 0.1 7.5e-09 35.4 0.0 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3176) FOLN PF09289.5 EGO53883.1 - 0.035 13.9 0.4 0.062 13.1 0.3 1.4 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain Toxin_20 PF08089.6 EGO53887.1 - 0.16 11.8 0.9 0.35 10.7 0.6 1.5 1 0 0 1 1 1 0 Huwentoxin-II family DUF2076 PF09849.4 EGO53887.1 - 3.9 7.4 8.2 0.11 12.5 1.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Glyco_hydro_76 PF03663.9 EGO53888.1 - 2e-154 514.4 6.4 2.6e-154 514.0 4.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EGO53888.1 - 0.024 13.6 7.5 0.77 8.7 0.2 3.1 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Gln-synt_C PF00120.19 EGO53889.1 - 1.1e-56 191.8 0.0 1.7e-56 191.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EGO53889.1 - 1e-25 90.8 0.3 2.5e-25 89.5 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase Membr_traf_MHD PF10540.4 EGO53890.1 - 1.4e-23 83.1 0.2 4.3e-23 81.6 0.2 1.9 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EGO53890.1 - 1e-16 60.5 0.0 3.6e-16 58.7 0.0 2.0 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.6 EGO53890.1 - 1.6e-06 26.6 1.2 3.2e-06 25.7 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF810) Lactonase PF10282.4 EGO53892.1 - 7.7e-91 304.7 0.1 1e-90 304.3 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SRP-alpha_N PF04086.8 EGO53894.1 - 0.21 10.9 0.7 0.26 10.6 0.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Nucleotid_trans PF03407.11 EGO53895.1 - 2.4e-08 34.0 0.0 3.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.7 EGO53895.1 - 0.015 14.8 1.0 0.024 14.1 0.7 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family MFS_1 PF07690.11 EGO53896.1 - 3.3e-35 121.4 16.1 4.9e-35 120.8 11.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EGO53897.1 - 1.7e-14 53.3 0.0 3.3e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO53897.1 - 1.2e-05 25.1 11.4 2.1e-05 24.2 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSP1_C PF07462.6 EGO53897.1 - 0.037 12.4 0.0 0.056 11.8 0.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus IF-2B PF01008.12 EGO53898.1 - 7.9e-17 61.1 0.2 1.9e-16 59.8 0.1 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.23 EGO53898.1 - 7.5e-07 28.8 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain PAN_4 PF14295.1 EGO53899.1 - 0.0003 20.4 0.6 0.00058 19.5 0.4 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EGO53899.1 - 0.014 15.1 0.4 0.032 13.9 0.3 1.5 1 0 0 1 1 1 0 PAN domain PAN_3 PF08277.7 EGO53899.1 - 0.032 13.8 0.4 0.07 12.7 0.3 1.5 1 0 0 1 1 1 0 PAN-like domain Sugar_tr PF00083.19 EGO53900.1 - 3.7e-69 233.4 13.0 4.5e-69 233.1 9.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO53900.1 - 4.4e-27 94.7 17.1 5.6e-27 94.3 11.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Tweety PF04906.8 EGO53900.1 - 0.04 12.3 0.0 0.061 11.7 0.0 1.4 1 0 0 1 1 1 0 Tweety Tetraspannin PF00335.15 EGO53901.1 - 6.8 5.8 5.8 9.8 5.3 4.1 1.3 1 0 0 1 1 1 0 Tetraspanin family MARVEL PF01284.18 EGO53902.1 - 0.00058 19.6 0.6 0.00076 19.3 0.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 EGO53902.1 - 0.03 14.0 5.3 0.038 13.6 3.7 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling OppC_N PF12911.2 EGO53902.1 - 0.28 10.6 1.9 0.84 9.0 1.1 1.9 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C F-box-like PF12937.2 EGO53903.1 - 0.011 15.4 0.9 0.041 13.6 0.0 2.6 2 1 0 2 2 2 0 F-box-like Glyco_hydro_16 PF00722.16 EGO53904.1 - 4.7e-10 39.0 1.4 8.9e-10 38.1 1.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CBM_1 PF00734.13 EGO53904.1 - 2.2e-09 36.7 13.9 2.2e-09 36.7 9.6 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain Lactamase_B PF00753.22 EGO53905.1 - 1.4e-06 28.1 0.4 3.8e-06 26.6 0.2 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGO53905.1 - 0.00013 21.5 0.2 0.002 17.7 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Methyltransf_23 PF13489.1 EGO53907.1 - 1.3e-11 44.4 0.0 2.4e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO53907.1 - 2.5e-10 40.9 0.0 9e-10 39.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO53907.1 - 3.6e-10 39.6 0.0 2.2e-09 37.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO53907.1 - 2.2e-08 34.4 0.0 1e-07 32.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO53907.1 - 4.7e-07 30.1 0.0 1.4e-06 28.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EGO53907.1 - 1.2e-05 25.4 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EGO53907.1 - 6.1e-05 23.3 0.0 0.00023 21.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO53907.1 - 0.00013 21.0 0.0 0.0002 20.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EGO53907.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EGO53907.1 - 0.0028 16.9 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Ubie_methyltran PF01209.13 EGO53907.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0258 PF06789.7 EGO53907.1 - 0.022 14.7 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) CMAS PF02353.15 EGO53907.1 - 0.028 13.4 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EGO53907.1 - 0.051 12.6 0.0 0.067 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGO53907.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FF PF01846.14 EGO53908.1 - 8.4e-07 28.8 13.2 6.1e-05 22.8 0.1 5.0 4 2 0 4 4 4 3 FF domain Glyco_hydro_10 PF00331.15 EGO53909.1 - 9.8e-82 274.5 0.0 1.2e-81 274.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 AA_permease PF00324.16 EGO53910.1 - 5.7e-131 437.1 35.7 7.2e-131 436.8 24.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO53910.1 - 5.2e-32 110.9 38.7 6.6e-32 110.5 26.4 1.3 1 1 0 1 1 1 1 Amino acid permease DLH PF01738.13 EGO53911.1 - 6.2e-29 100.8 0.0 7.3e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGO53911.1 - 4.9e-06 26.3 0.0 6.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_M42 PF05343.9 EGO53911.1 - 0.005 15.6 0.0 0.0069 15.1 0.0 1.1 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Abhydrolase_6 PF12697.2 EGO53911.1 - 0.077 12.8 0.0 11 5.8 0.0 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family Acetyltransf_1 PF00583.19 EGO53912.1 - 2.1e-07 30.8 0.0 5.3e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGO53912.1 - 3.7e-05 23.7 0.0 8.7e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO53912.1 - 0.00014 21.9 0.0 0.00028 20.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO53912.1 - 0.0061 16.4 0.0 0.0096 15.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGO53912.1 - 0.052 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF747 PF05346.6 EGO53913.1 - 6.7e-136 452.6 0.3 9.1e-136 452.2 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family GP41 PF00517.12 EGO53913.1 - 0.084 12.4 0.1 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral envelope protein TRI5 PF06330.6 EGO53914.1 - 0.00039 19.1 0.2 0.38 9.3 0.0 2.1 2 0 0 2 2 2 2 Trichodiene synthase (TRI5) ING PF12998.2 EGO53914.1 - 0.0075 16.5 0.0 0.48 10.7 0.0 2.5 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding AMP-binding PF00501.23 EGO53918.1 - 4.2e-243 806.1 0.0 3e-87 292.7 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EGO53918.1 - 7.3e-182 602.9 0.0 1.9e-31 109.0 0.0 7.7 7 1 0 7 7 7 7 Condensation domain PP-binding PF00550.20 EGO53918.1 - 1.9e-59 197.7 7.6 5.2e-10 39.4 0.0 7.2 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EGO53918.1 - 1.8e-17 64.0 0.6 6.2e-07 30.2 0.1 4.7 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.11 EGO53918.1 - 4.9e-05 23.0 1.1 5 6.6 0.0 4.9 5 0 0 5 5 5 2 Wax ester synthase-like Acyl-CoA acyltransferase domain HxxPF_rpt PF13745.1 EGO53918.1 - 0.0022 18.2 1.2 0.46 10.8 0.0 4.4 5 0 0 5 5 5 1 HxxPF-repeated domain Transferase PF02458.10 EGO53918.1 - 0.0058 15.1 0.0 0.71 8.2 0.0 3.7 4 0 0 4 4 4 1 Transferase family AATase PF07247.7 EGO53918.1 - 0.051 12.1 1.0 5.4 5.4 0.0 4.1 5 0 0 5 5 5 0 Alcohol acetyltransferase Requiem_N PF14051.1 EGO53918.1 - 0.24 11.3 0.0 0.54 10.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. K_oxygenase PF13434.1 EGO53919.1 - 5e-107 357.7 0.0 1.1e-106 356.6 0.0 1.5 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EGO53919.1 - 3.1e-10 40.4 0.0 2.1e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO53919.1 - 8.2e-08 32.1 0.0 3.1e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGO53919.1 - 0.00047 20.1 0.0 0.0055 16.6 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF4470 PF14737.1 EGO53920.1 - 2.5e-19 68.8 0.0 6.1e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EGO53920.1 - 1.1e-10 41.2 14.4 2.7e-10 39.9 10.0 1.7 1 0 0 1 1 1 1 MYND finger HET PF06985.6 EGO53921.1 - 6.8e-36 123.4 0.1 1.2e-35 122.6 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2272 PF10030.4 EGO53921.1 - 0.099 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) DUF4470 PF14737.1 EGO53922.1 - 1.7e-09 37.3 0.4 3.6e-07 29.8 0.1 2.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EGO53923.1 - 0.0016 18.2 10.9 0.004 16.9 7.6 1.8 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EGO53923.1 - 0.028 13.6 4.1 0.022 14.0 1.3 1.9 1 1 1 2 2 2 0 Life-span regulatory factor GMC_oxred_N PF00732.14 EGO53924.1 - 4.4e-57 193.4 0.0 1.2e-56 192.0 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EGO53924.1 - 1.1e-07 31.0 0.0 3.1e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO53924.1 - 1.4e-06 27.4 0.1 0.0046 15.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain GMC_oxred_C PF05199.8 EGO53924.1 - 4.4e-05 23.7 0.0 8.9e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EGO53924.1 - 7.5e-05 22.6 0.1 0.00018 21.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGO53924.1 - 0.00084 18.3 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EGO53924.1 - 0.038 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO53924.1 - 0.057 11.8 0.0 0.094 11.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 EGO53924.1 - 0.11 11.0 0.0 0.37 9.3 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EGO53925.1 - 0.00014 21.6 0.0 0.0026 17.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGO53925.1 - 0.00045 20.1 0.0 0.0055 16.6 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO53925.1 - 0.0019 17.1 0.1 0.0039 16.1 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO53925.1 - 0.0062 16.6 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 EGO53925.1 - 0.013 15.1 0.1 0.59 9.6 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain NAD_binding_8 PF13450.1 EGO53925.1 - 0.055 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGO53925.1 - 0.086 11.7 0.0 0.18 10.6 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Lactamase_B PF00753.22 EGO53926.1 - 1.1e-18 67.6 0.3 1.6e-18 67.0 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGO53926.1 - 0.04 13.4 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain F-box PF00646.28 EGO53927.1 - 4.7e-05 22.9 0.1 0.00014 21.4 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGO53927.1 - 0.013 15.2 0.1 0.013 15.2 0.1 2.2 2 0 0 2 2 2 0 F-box-like F-box-like_2 PF13013.1 EGO53927.1 - 0.038 13.7 0.7 0.14 11.8 0.1 2.1 2 0 0 2 2 2 0 F-box-like domain HypA PF01155.14 EGO53928.1 - 0.026 14.1 2.0 0.097 12.3 0.1 2.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family RNHCP PF12647.2 EGO53928.1 - 0.033 14.0 1.3 0.047 13.5 0.9 1.3 1 1 0 1 1 1 0 RNHCP domain DZR PF12773.2 EGO53928.1 - 0.18 11.6 4.1 2.4 8.0 2.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_S27e PF01667.12 EGO53928.1 - 0.54 9.8 4.3 2.1 7.9 0.1 2.5 3 0 0 3 3 3 0 Ribosomal protein S27 DNA_RNApol_7kD PF03604.8 EGO53928.1 - 1.3 8.5 3.9 1.1 8.8 0.8 2.1 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DUF1469 PF07332.6 EGO53929.1 - 0.1 12.3 4.6 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Methyltransf_23 PF13489.1 EGO53932.1 - 6.9e-20 71.3 0.0 1.3e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO53932.1 - 3.5e-11 42.9 0.0 7.7e-11 41.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO53932.1 - 8e-11 42.2 0.0 1.8e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO53932.1 - 1.7e-10 41.2 0.0 5.4e-10 39.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO53932.1 - 1.1e-08 35.6 0.1 1.4e-07 32.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO53932.1 - 1.1e-07 32.1 0.0 3.6e-07 30.4 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO53932.1 - 5.5e-06 25.6 0.0 0.0001 21.4 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EGO53932.1 - 0.0001 21.3 0.0 0.00029 19.9 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EGO53932.1 - 0.00015 21.7 0.0 0.00035 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO53932.1 - 0.0029 16.7 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EGO53932.1 - 0.0059 16.6 0.0 0.013 15.5 0.0 1.5 2 0 0 2 2 1 1 FtsJ-like methyltransferase MTS PF05175.9 EGO53932.1 - 0.0068 15.8 0.0 0.02 14.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EGO53932.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.8 EGO53932.1 - 0.032 13.5 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Histone methylation protein DOT1 DUF938 PF06080.7 EGO53932.1 - 0.055 12.9 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CMAS PF02353.15 EGO53932.1 - 0.062 12.3 0.0 0.2 10.6 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EGO53932.1 - 0.1 11.7 0.0 0.45 9.6 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase DREV PF05219.7 EGO53932.1 - 0.14 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase ADK PF00406.17 EGO53933.1 - 2e-26 92.6 0.0 2.3e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EGO53933.1 - 1e-07 32.3 0.0 1.5e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO53933.1 - 9.5e-07 28.7 0.1 3.4e-06 26.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO53933.1 - 0.00017 22.3 0.0 0.00026 21.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 EGO53933.1 - 0.0023 17.3 0.1 0.89 8.9 0.0 2.1 2 0 0 2 2 2 2 Dephospho-CoA kinase AAA_19 PF13245.1 EGO53933.1 - 0.0042 16.7 0.1 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EGO53933.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGO53933.1 - 0.016 15.1 0.2 0.046 13.6 0.1 1.7 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 EGO53933.1 - 0.019 14.0 0.1 0.052 12.6 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.1 EGO53933.1 - 0.045 13.2 0.1 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 EGO53933.1 - 0.053 13.4 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EGO53933.1 - 0.092 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EGO53933.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.5 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.12 EGO53933.1 - 0.14 11.6 0.1 0.4 10.1 0.1 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EGO53933.1 - 0.15 11.4 0.1 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain Cerato-platanin PF07249.7 EGO53934.1 - 0.037 14.0 0.1 0.067 13.1 0.1 1.5 1 0 0 1 1 1 0 Cerato-platanin Cerato-platanin PF07249.7 EGO53936.1 - 1.3e-05 25.1 0.3 1.3e-05 25.1 0.2 2.0 2 0 0 2 2 2 1 Cerato-platanin NUDIX PF00293.23 EGO53937.1 - 8.4e-18 64.3 0.0 1e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EGO53937.1 - 0.00045 19.6 0.1 0.0025 17.2 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain Peptidase_M20 PF01546.23 EGO53938.1 - 0.0002 20.9 7.3 0.00045 19.7 5.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGO53938.1 - 0.00039 20.1 0.1 0.00094 18.9 0.1 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF1996 PF09362.5 EGO53939.1 - 7.7e-95 317.0 1.7 1e-94 316.6 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ank_2 PF12796.2 EGO53940.1 - 1e-33 115.4 0.0 3.7e-09 36.8 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EGO53940.1 - 7.1e-29 98.1 6.0 5.9e-06 25.8 0.0 6.7 6 1 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EGO53940.1 - 8.2e-23 78.2 0.3 0.0077 16.3 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EGO53940.1 - 3.8e-19 68.2 0.3 6.6e-05 23.0 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGO53940.1 - 1.1e-16 60.7 0.5 0.0026 18.2 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeats (many copies) FAD_binding_3 PF01494.14 EGO53943.1 - 4.4e-15 55.5 1.8 4.4e-08 32.5 0.1 3.1 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGO53943.1 - 2e-09 36.8 0.0 0.00037 19.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO53943.1 - 2.1e-09 36.7 0.2 2.2e-08 33.3 0.0 2.0 1 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EGO53943.1 - 2.8e-07 30.6 0.1 9.8e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO53943.1 - 7.7e-07 29.0 0.0 2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EGO53943.1 - 4.4e-06 26.0 0.4 0.00012 21.3 0.0 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EGO53943.1 - 6.9e-06 25.1 0.1 0.0053 15.6 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.9 EGO53943.1 - 1.2e-05 23.9 0.0 0.00087 17.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 EGO53943.1 - 4.3e-05 23.1 0.0 0.0004 20.0 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EGO53943.1 - 0.00025 20.0 0.0 0.059 12.2 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.12 EGO53943.1 - 0.0089 15.1 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EGO53943.1 - 0.019 15.3 0.1 0.4 11.1 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO53943.1 - 0.028 14.4 0.0 0.14 12.2 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGO53943.1 - 0.041 12.4 0.0 1.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Tryptophan halogenase p450 PF00067.17 EGO53944.1 - 1.4e-49 168.9 0.0 2e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1772 PF08592.6 EGO53945.1 - 8e-16 58.0 1.9 1.1e-15 57.5 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) SnoaL_2 PF12680.2 EGO53946.1 - 0.0026 18.1 0.0 0.0055 17.0 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EGO53946.1 - 0.0093 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase NmrA PF05368.8 EGO53947.1 - 2.1e-30 105.6 0.0 3.2e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO53947.1 - 1.1e-08 35.2 0.0 2.8e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO53947.1 - 0.0026 17.2 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO53947.1 - 0.0084 14.8 0.0 0.014 14.1 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGO53947.1 - 0.024 13.5 0.0 0.23 10.3 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein adh_short PF00106.20 EGO53947.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase PBP1_TM PF14812.1 EGO53949.1 - 0.17 12.1 1.8 0.24 11.7 1.2 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF629 PF04780.7 EGO53951.1 - 0.091 11.2 0.2 5.1 5.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) tRNA-synt_2 PF00152.15 EGO53955.1 - 7.3e-75 251.8 0.0 1.2e-74 251.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EGO53955.1 - 2e-21 76.1 0.0 3e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EGO53955.1 - 7e-08 32.2 0.1 1.9e-07 30.8 0.1 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGO53955.1 - 0.00095 18.4 0.1 0.51 9.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF3492 PF11997.3 EGO53955.1 - 0.02 14.4 0.3 0.042 13.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Abhydrolase_3 PF07859.8 EGO53956.1 - 2.6e-46 157.8 0.0 3.3e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EGO53956.1 - 5.8e-07 28.6 0.0 9e-07 27.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EGO53956.1 - 0.00074 19.2 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGO53956.1 - 0.0039 16.6 0.1 0.046 13.1 0.1 2.1 1 1 0 1 1 1 1 Putative esterase DUF2974 PF11187.3 EGO53956.1 - 0.034 13.5 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 EGO53956.1 - 0.039 13.1 0.0 0.37 9.9 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family GFO_IDH_MocA PF01408.17 EGO53957.1 - 1.1e-08 35.5 0.0 2.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGO53957.1 - 0.085 12.6 0.0 5.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain DivIVA PF05103.8 EGO53958.1 - 0.011 15.8 1.7 0.018 15.1 0.2 1.9 1 1 1 2 2 2 0 DivIVA protein AAA_13 PF13166.1 EGO53958.1 - 0.09 11.2 1.4 0.13 10.6 1.0 1.2 1 0 0 1 1 1 0 AAA domain EnY2 PF10163.4 EGO53958.1 - 0.21 11.5 1.8 3.7 7.5 1.3 2.7 1 1 1 2 2 2 0 Transcription factor e(y)2 DUF1664 PF07889.7 EGO53958.1 - 0.31 10.8 2.1 1.3 8.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Stn1 PF10451.4 EGO53959.1 - 6.8e-15 54.5 3.8 6.3e-14 51.4 2.7 2.0 1 1 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 EGO53959.1 - 4.9e-07 29.5 0.0 1.4e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain RepA_C PF04796.7 EGO53959.1 - 0.016 14.8 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Plasmid encoded RepA protein Sbi-IV PF11621.3 EGO53960.1 - 0.21 11.7 0.1 6.9 6.9 0.0 2.5 2 0 0 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI Glyco_hydro_81 PF03639.8 EGO53961.1 - 8.6e-182 605.7 0.8 1.2e-181 605.3 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Na_Ca_ex PF01699.19 EGO53962.1 - 1.5e-50 170.4 29.8 2.9e-26 91.7 7.5 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein FA_desaturase PF00487.19 EGO53962.1 - 0.025 14.0 0.2 0.025 14.0 0.2 2.4 4 0 0 4 4 4 0 Fatty acid desaturase DUF1129 PF06570.6 EGO53962.1 - 0.12 11.7 2.4 0.75 9.0 1.7 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Patatin PF01734.17 EGO53963.1 - 2.6e-10 40.5 0.0 7.6e-09 35.7 0.0 2.7 1 1 0 1 1 1 1 Patatin-like phospholipase HeLo PF14479.1 EGO53964.1 - 2.4e-45 154.9 3.9 2.6e-43 148.2 2.7 2.3 1 1 0 1 1 1 1 Prion-inhibition and propagation FAD_binding_4 PF01565.18 EGO53965.1 - 9.5e-17 60.7 0.0 1.4e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Rcd1 PF04078.8 EGO53967.1 - 1.4e-131 437.0 4.9 1.8e-131 436.7 3.4 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like OSCP PF00213.13 EGO53967.1 - 0.31 10.8 2.9 1.6 8.5 0.0 2.7 3 0 0 3 3 3 0 ATP synthase delta (OSCP) subunit V-ATPase_H_N PF03224.9 EGO53967.1 - 0.89 8.6 5.5 6 5.8 0.1 3.0 1 1 0 2 2 2 0 V-ATPase subunit H DEAD PF00270.24 EGO53968.1 - 2.7e-38 131.1 0.1 6.9e-38 129.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO53968.1 - 4.6e-23 80.8 0.3 1.1e-13 50.8 0.1 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Ycf1 PF05758.7 EGO53968.1 - 8.2e-06 23.8 5.2 8.2e-06 23.8 3.6 2.1 2 0 0 2 2 2 1 Ycf1 ResIII PF04851.10 EGO53968.1 - 2.4e-05 24.2 0.0 2.4e-05 24.2 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Spore_coat_CotO PF14153.1 EGO53968.1 - 0.025 14.0 30.4 0.035 13.5 15.1 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Pox_Ag35 PF03286.9 EGO53968.1 - 1.1 8.7 35.7 0.26 10.7 18.1 2.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RRM_1 PF00076.17 EGO53969.1 - 7e-24 83.2 0.1 1.3e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO53969.1 - 1.5e-18 66.5 0.0 1.1e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO53969.1 - 2.6e-14 52.8 0.1 3.7e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGO53969.1 - 0.075 12.8 0.1 0.16 11.7 0.0 1.5 2 0 0 2 2 2 0 RNA binding motif Na_H_Exchanger PF00999.16 EGO53970.1 - 1.2e-67 228.1 43.3 1.7e-67 227.6 30.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_hydro_47 PF01532.15 EGO53971.1 - 1.1e-137 459.3 0.0 1.3e-137 459.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rad10 PF03834.9 EGO53972.1 - 8e-31 105.5 0.1 1.2e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EGO53972.1 - 0.018 15.2 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain MR_MLE_C PF13378.1 EGO53974.1 - 2e-18 66.4 0.0 5.8e-18 64.8 0.0 1.9 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EGO53974.1 - 3e-13 50.0 0.0 9.8e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EGO53974.1 - 0.00023 21.1 0.0 0.0005 20.0 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 EGO53974.1 - 0.001 18.0 0.0 0.0022 16.9 0.0 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus UPF0150 PF03681.10 EGO53974.1 - 0.069 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) dCMP_cyt_deam_1 PF00383.17 EGO53975.1 - 2e-14 53.0 0.0 2.7e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EGO53975.1 - 0.1 12.1 0.0 0.14 11.8 0.0 1.3 1 1 0 1 1 1 0 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 EGO53975.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.6 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase DnaJ PF00226.26 EGO53976.1 - 3.4e-22 77.9 1.0 1.1e-21 76.2 0.7 2.0 1 0 0 1 1 1 1 DnaJ domain SIMPL PF04402.9 EGO53976.1 - 0.014 15.2 0.8 0.026 14.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF541) DUF493 PF04359.9 EGO53976.1 - 0.09 13.1 0.1 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF493) Asp PF00026.18 EGO53977.1 - 1.4e-54 185.4 0.0 1.7e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO53977.1 - 7.2e-08 32.5 1.9 1.7e-07 31.3 0.0 2.6 4 0 0 4 4 4 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EGO53977.1 - 0.019 14.4 0.0 0.3 10.5 0.0 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Pkinase PF00069.20 EGO53978.1 - 8.6e-48 162.7 0.0 1.2e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO53978.1 - 1.1e-24 86.9 0.0 1.6e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO53978.1 - 0.00042 19.3 0.0 0.00065 18.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO53978.1 - 0.018 14.7 0.2 0.018 14.7 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EGO53978.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.8 EGO53978.1 - 0.73 9.6 10.7 0.99 9.2 7.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 EGO53978.1 - 5 5.2 12.6 6.8 4.8 8.8 1.0 1 0 0 1 1 1 0 Transmembrane protein zf-RING_2 PF13639.1 EGO53980.1 - 1e-09 38.0 9.3 1.6e-09 37.4 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGO53980.1 - 1.7e-07 31.2 2.7 3.3e-07 30.3 1.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGO53980.1 - 7.7e-06 25.6 2.2 1.4e-05 24.8 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EGO53980.1 - 0.00011 21.7 5.5 0.00022 20.8 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO53980.1 - 0.00083 19.3 8.1 0.0014 18.5 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO53980.1 - 0.0021 17.6 6.4 0.0038 16.8 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO53980.1 - 0.052 13.2 6.4 0.13 11.9 4.4 1.7 1 1 0 1 1 1 0 zinc-RING finger domain Med24_N PF11277.3 EGO53980.1 - 0.098 10.1 0.0 0.12 9.8 0.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Med12-PQL PF12144.3 EGO53980.1 - 0.098 12.0 0.7 0.13 11.6 0.5 1.1 1 0 0 1 1 1 0 Eukaryotic Mediator 12 catenin-binding domain Tmpp129 PF10272.4 EGO53980.1 - 0.13 10.9 3.7 0.77 8.4 3.1 1.8 1 1 1 2 2 2 0 Putative transmembrane protein precursor Preseq_ALAS PF09029.5 EGO53980.1 - 0.26 11.3 2.3 0.59 10.1 0.3 2.4 2 1 1 3 3 3 0 5-aminolevulinate synthase presequence Rad50_zn_hook PF04423.9 EGO53980.1 - 0.32 10.4 4.0 7.1 6.1 0.4 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.1 EGO53980.1 - 0.79 9.3 9.2 10 5.7 6.1 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.7 EGO53980.1 - 0.97 9.6 5.9 15 5.8 0.0 2.8 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_60s PF00428.14 EGO53980.1 - 1.1 9.7 6.7 2.2 8.7 4.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Abhydrolase_3 PF07859.8 EGO53981.1 - 4e-41 140.9 0.0 1.1e-31 110.0 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EGO53981.1 - 1.2e-14 53.7 0.0 4.1e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGO53981.1 - 0.0032 17.2 0.0 0.0071 16.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO53981.1 - 0.0044 16.9 0.0 0.0087 15.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EGO53981.1 - 0.012 14.3 0.0 0.6 8.7 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Utp14 PF04615.8 EGO53982.1 - 2.3e-196 654.2 64.4 2.3e-196 654.2 44.6 2.2 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.4 EGO53983.1 - 7.1e-17 61.0 0.5 8.7e-17 60.7 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Pkinase PF00069.20 EGO53985.1 - 1.2e-35 122.9 0.0 1.4e-35 122.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO53985.1 - 9e-12 44.6 0.0 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGO53985.1 - 0.036 13.1 0.0 0.068 12.2 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGO53985.1 - 0.081 11.8 0.0 2.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like YrbL-PhoP_reg PF10707.4 EGO53985.1 - 0.099 11.9 0.0 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL FAD_binding_3 PF01494.14 EGO53987.1 - 3.8e-17 62.3 0.3 4.4e-12 45.7 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGO53987.1 - 2.3e-09 36.6 3.2 3.6e-06 26.1 0.3 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO53987.1 - 5.2e-07 29.5 0.1 2.1e-06 27.6 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO53987.1 - 2.7e-06 26.5 0.1 5.8e-06 25.4 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EGO53987.1 - 2.9e-06 27.5 0.0 0.0009 19.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO53987.1 - 2.1e-05 24.5 0.1 0.00098 19.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO53987.1 - 0.00018 20.1 0.0 0.0015 17.0 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 EGO53987.1 - 0.00025 20.2 0.0 0.51 9.3 0.0 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EGO53987.1 - 0.00053 19.1 0.8 0.0024 17.0 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EGO53987.1 - 0.0026 16.6 0.3 0.0052 15.6 0.2 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EGO53987.1 - 0.0031 16.2 0.0 1.9 7.0 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 EGO53987.1 - 0.0057 16.7 0.0 0.017 15.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO53987.1 - 0.016 14.9 0.1 1.2 8.8 0.0 2.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EGO53987.1 - 0.025 13.5 0.0 6.2 5.6 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 EGO53987.1 - 0.088 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain p450 PF00067.17 EGO53988.1 - 1.1e-64 218.7 0.0 8.7e-64 215.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EGO53989.1 - 7.8e-70 235.6 22.9 9.7e-70 235.3 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO53989.1 - 3.1e-19 68.9 31.3 7e-19 67.7 21.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3522 PF12036.3 EGO53989.1 - 0.41 10.4 7.2 6.7 6.4 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3522) DUF1129 PF06570.6 EGO53989.1 - 1.2 8.3 13.3 0.023 14.0 1.7 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1129) Aldedh PF00171.17 EGO53990.1 - 3e-162 540.1 0.1 3.4e-162 539.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGO53990.1 - 0.0039 16.4 0.0 0.35 10.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.9 EGO53990.1 - 0.006 15.3 0.3 0.029 13.1 0.2 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) RicinB_lectin_2 PF14200.1 EGO53993.1 - 2.5e-29 101.7 3.0 4.3e-15 55.9 0.3 2.8 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EGO53993.1 - 0.00027 20.9 0.7 0.00093 19.2 0.1 2.2 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Trehalase PF01204.13 EGO53993.1 - 0.0033 16.1 0.1 0.005 15.5 0.1 1.2 1 0 0 1 1 1 1 Trehalase F5_F8_type_C PF00754.20 EGO53993.1 - 0.0038 17.0 0.0 0.015 15.1 0.0 2.1 1 1 0 1 1 1 1 F5/8 type C domain EnY2 PF10163.4 EGO53995.1 - 0.037 13.9 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 Transcription factor e(y)2 Trp_DMAT PF11991.3 EGO53997.1 - 2e-37 129.2 0.1 1.2e-26 93.8 0.1 2.2 1 1 1 2 2 2 2 Tryptophan dimethylallyltransferase Pyridox_ox_2 PF12900.2 EGO53997.1 - 9.6e-36 122.7 0.0 1.5e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HET PF06985.6 EGO53998.1 - 8.9e-30 103.6 0.2 1.7e-29 102.7 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_11 PF08241.7 EGO53999.1 - 1.6e-25 89.3 0.0 2.5e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO53999.1 - 6.2e-25 87.5 0.0 8.4e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO53999.1 - 3.1e-17 62.8 0.0 4.8e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO53999.1 - 6.8e-16 58.0 0.0 9.1e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EGO53999.1 - 1.8e-15 57.0 0.0 3.5e-15 56.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO53999.1 - 7.3e-15 55.5 0.0 1.2e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO53999.1 - 1e-14 54.6 0.0 1.8e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO53999.1 - 1.4e-08 34.7 0.0 2.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO53999.1 - 4.9e-07 29.2 0.0 8.2e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 EGO53999.1 - 3.3e-06 26.5 0.0 0.055 12.7 0.0 2.2 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain MetW PF07021.7 EGO53999.1 - 3.5e-06 26.5 0.0 6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 EGO53999.1 - 0.0002 20.9 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.11 EGO53999.1 - 0.0002 19.8 0.0 0.00044 18.7 0.0 1.5 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EGO53999.1 - 0.00089 18.3 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 EGO53999.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 EGO53999.1 - 0.0012 18.3 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.8 EGO53999.1 - 0.0024 17.0 0.0 0.0033 16.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EGO53999.1 - 0.0025 16.9 0.0 0.0084 15.1 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase DREV PF05219.7 EGO53999.1 - 0.0034 16.3 0.0 0.0066 15.3 0.0 1.4 1 1 0 1 1 1 1 DREV methyltransferase NodS PF05401.6 EGO53999.1 - 0.0045 16.4 0.0 0.0065 15.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) FtsJ PF01728.14 EGO53999.1 - 0.019 14.9 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CN_hydrolase PF00795.17 EGO54001.1 - 9.4e-39 132.6 0.0 1.2e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Spermine_synth PF01564.12 EGO54002.1 - 5.3e-09 35.3 0.0 7.9e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 EGO54002.1 - 2.4e-06 27.5 0.0 4.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO54002.1 - 0.00052 20.5 0.0 0.00096 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO54002.1 - 0.00079 19.1 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO54002.1 - 0.0092 16.4 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.6 EGO54002.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase PEMT PF04191.8 EGO54003.1 - 8.8e-31 106.1 5.7 1.6e-30 105.3 3.1 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 EGO54003.1 - 0.031 14.0 0.8 0.074 12.8 0.1 1.9 2 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase DUF202 PF02656.10 EGO54003.1 - 0.32 11.2 5.2 3 8.1 0.7 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF1651 PF07864.6 EGO54008.1 - 0.084 12.9 1.4 0.2 11.7 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1651) DUF4417 PF14386.1 EGO54013.1 - 0.065 12.5 0.0 0.067 12.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4417) DSPc PF00782.15 EGO54013.1 - 0.14 11.7 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Cytomega_UL20A PF05984.7 EGO54017.1 - 2.1 8.5 7.1 0.24 11.6 1.9 1.7 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein DDHD PF02862.12 EGO54020.1 - 8.4 6.1 8.6 28 4.4 3.4 2.2 2 0 0 2 2 2 0 DDHD domain DUF4551 PF15087.1 EGO54021.1 - 2.6 6.3 5.6 3.8 5.7 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF2458 PF10454.4 EGO54022.1 - 0.018 14.9 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DUF2533 PF10752.4 EGO54022.1 - 0.056 13.7 0.2 0.094 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) DUF1140 PF06600.6 EGO54022.1 - 0.057 13.5 0.8 0.41 10.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) Stathmin PF00836.14 EGO54022.1 - 0.061 12.9 0.1 0.099 12.2 0.1 1.4 1 0 0 1 1 1 0 Stathmin family CBP4 PF07960.6 EGO54022.1 - 0.15 11.7 0.7 0.18 11.4 0.5 1.1 1 0 0 1 1 1 0 CBP4 Nop14 PF04147.7 EGO54026.1 - 0.42 8.4 38.5 0.42 8.4 26.7 1.0 1 0 0 1 1 1 0 Nop14-like family YqfQ PF14181.1 EGO54026.1 - 0.58 10.1 20.5 0.6 10.1 14.2 1.2 1 0 0 1 1 1 0 YqfQ-like protein DUF2457 PF10446.4 EGO54026.1 - 0.78 8.3 34.6 0.79 8.3 23.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Spore_coat_CotO PF14153.1 EGO54026.1 - 1.1 8.7 29.1 1 8.7 20.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SURF6 PF04935.7 EGO54026.1 - 1.2 8.4 22.8 1.2 8.3 15.8 1.1 1 0 0 1 1 1 0 Surfeit locus protein 6 DUF1510 PF07423.6 EGO54026.1 - 1.2 8.4 29.6 1.2 8.4 20.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2052 PF09747.4 EGO54026.1 - 1.3 8.9 31.5 1.4 8.8 21.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Sigma70_ner PF04546.8 EGO54026.1 - 2.2 7.8 30.0 2.8 7.4 20.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Paf1 PF03985.8 EGO54026.1 - 2.3 6.8 36.8 2.3 6.8 25.5 1.0 1 0 0 1 1 1 0 Paf1 SpoIIIAH PF12685.2 EGO54026.1 - 2.4 7.6 14.7 2.3 7.6 10.2 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2413 PF10310.4 EGO54026.1 - 3.9 6.1 19.6 3.8 6.2 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Daxx PF03344.10 EGO54026.1 - 4.1 5.7 39.8 4.5 5.6 27.6 1.2 1 0 0 1 1 1 0 Daxx Family Vfa1 PF08432.5 EGO54026.1 - 4.9 7.1 23.0 5.4 7.0 15.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDRGK PF09756.4 EGO54026.1 - 5.2 6.4 36.0 5.4 6.3 25.0 1.1 1 0 0 1 1 1 0 DDRGK domain BUD22 PF09073.5 EGO54026.1 - 5.3 6.0 29.8 5.3 6.0 20.7 1.1 1 0 0 1 1 1 0 BUD22 AUX_IAA PF02309.11 EGO54026.1 - 5.5 6.6 9.0 5.5 6.6 6.2 1.1 1 0 0 1 1 1 0 AUX/IAA family DDHD PF02862.12 EGO54026.1 - 5.7 6.6 19.6 6.6 6.4 13.6 1.1 1 0 0 1 1 1 0 DDHD domain RRN3 PF05327.6 EGO54026.1 - 8.5 4.3 21.3 8.5 4.3 14.8 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 EGO54026.1 - 9.1 4.1 31.6 9.8 4.0 21.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.6 EGO54026.1 - 9.3 6.1 49.4 8.7 6.1 34.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SpoIIP PF07454.6 EGO54026.1 - 9.9 5.2 15.3 9.9 5.2 10.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PA28_alpha PF02251.13 EGO54027.1 - 0.027 14.6 0.3 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit DUF4570 PF15134.1 EGO54027.1 - 0.15 11.9 0.9 0.3 10.9 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) WD40 PF00400.27 EGO54028.1 - 3.9e-168 540.1 46.9 1.3e-16 59.7 0.5 11.8 11 1 1 12 12 11 11 WD domain, G-beta repeat NACHT PF05729.7 EGO54028.1 - 1.5e-28 99.5 0.0 2.6e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 EGO54028.1 - 6e-18 64.0 5.3 12 5.7 0.0 11.3 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 EGO54028.1 - 5.8e-16 58.6 15.9 0.00081 18.8 0.3 7.1 1 1 8 9 9 9 7 Lipoprotein LpqB beta-propeller domain eIF2A PF08662.6 EGO54028.1 - 3.7e-12 46.3 0.0 0.0082 15.8 0.0 4.5 1 1 5 6 6 6 6 Eukaryotic translation initiation factor eIF2A DUF1652 PF07865.6 EGO54028.1 - 4.7e-10 38.9 0.0 34 4.1 0.0 9.4 4 4 6 10 10 10 0 Protein of unknown function (DUF1652) SRP9-21 PF05486.7 EGO54028.1 - 9.5e-08 31.6 0.0 1.3e+02 2.3 0.0 8.9 9 0 0 9 9 9 0 Signal recognition particle 9 kDa protein (SRP9) B9-C2 PF07162.6 EGO54028.1 - 2.3e-06 27.4 0.1 2 8.1 0.0 7.9 10 0 0 10 10 10 1 Ciliary basal body-associated, B9 protein Cytochrom_D1 PF02239.11 EGO54028.1 - 2.5e-06 26.0 0.0 0.52 8.5 0.0 3.9 1 1 2 4 4 4 2 Cytochrome D1 heme domain Nbas_N PF15492.1 EGO54028.1 - 5.2e-06 25.7 12.5 8.2 5.4 0.0 9.0 1 1 6 9 9 9 1 Neuroblastoma-amplified sequence, N terminal AAA_22 PF13401.1 EGO54028.1 - 0.0017 18.4 0.0 0.004 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EGO54028.1 - 0.005 17.0 0.0 0.016 15.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGO54028.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain NQRA PF05896.6 EGO54028.1 - 0.026 13.7 0.0 9.3 5.3 0.0 3.3 2 2 1 3 3 3 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DASH_Spc34 PF08657.5 EGO54028.1 - 0.05 13.2 0.1 2.6e+02 1.0 0.0 5.5 7 0 0 7 7 7 0 DASH complex subunit Spc34 AAA_11 PF13086.1 EGO54028.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EGO54028.1 - 0.13 11.2 0.0 0.67 8.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Proteasome_A_N PF10584.4 EGO54028.1 - 0.23 10.7 14.6 4.1e+02 0.4 0.0 9.5 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature TPR_10 PF13374.1 EGO54029.1 - 2.4e-16 59.0 0.1 1.5e-13 50.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO54029.1 - 2.8e-15 55.9 0.5 2.4e-07 30.5 0.0 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat DUF2664 PF10867.3 EGO54029.1 - 0.1 13.2 0.1 4 8.1 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2664) TPR_11 PF13414.1 EGO54029.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 TPR repeat Ank_4 PF13637.1 EGO54030.1 - 1.5e-18 66.7 0.1 2.8e-09 37.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO54030.1 - 6.6e-18 64.8 0.2 7.4e-18 64.6 0.1 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGO54030.1 - 3.4e-16 58.1 0.1 4.5e-05 23.0 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EGO54030.1 - 2e-12 46.0 0.0 0.00011 22.0 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EGO54030.1 - 1.5e-11 44.1 0.0 2.2e-05 24.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Head_binding PF09008.5 EGO54030.1 - 0.032 14.2 0.1 4.9 7.2 0.0 2.0 1 1 1 2 2 2 0 Head binding zf-CHY PF05495.7 EGO54032.1 - 1.2e-16 60.6 27.2 1.7e-15 56.9 11.1 3.4 3 0 0 3 3 3 2 CHY zinc finger Mu-like_Com PF10122.4 EGO54032.1 - 4.1e-05 22.5 0.7 4.1e-05 22.5 0.5 2.6 2 0 0 2 2 2 1 Mu-like prophage protein Com DEPP PF15343.1 EGO54032.1 - 0.099 12.2 3.4 0.16 11.5 0.1 2.5 2 1 0 2 2 2 0 Decidual protein induced by progesterone family DUF3295 PF11702.3 EGO54034.1 - 2.9e-187 623.6 25.7 4e-187 623.2 17.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EGO54034.1 - 3.7e-12 45.6 2.3 7e-12 44.7 1.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) NIR_SIR PF01077.17 EGO54037.1 - 6.4e-28 97.0 0.1 1.4e-27 95.9 0.0 1.7 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 EGO54037.1 - 3.7e-27 95.5 0.0 8.2e-27 94.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO54037.1 - 1.1e-13 51.3 8.0 3e-13 49.9 2.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 EGO54037.1 - 5.3e-13 48.7 1.4 2.5e-10 40.2 0.9 2.6 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.1 EGO54037.1 - 6.8e-13 48.2 0.0 3.7e-06 26.6 0.0 3.1 3 0 0 3 3 3 2 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.12 EGO54037.1 - 9.2e-09 34.8 0.0 1.9e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.21 EGO54037.1 - 1.5e-07 30.8 0.9 1.5e-07 30.8 0.6 2.8 3 1 0 3 3 3 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EGO54037.1 - 1.6e-05 25.0 0.3 0.038 14.0 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO54037.1 - 0.00084 19.1 0.5 1 9.1 0.1 3.5 2 1 1 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EGO54037.1 - 0.093 11.6 0.0 0.38 9.6 0.0 1.8 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EGO54037.1 - 0.097 12.9 0.4 21 5.4 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.1 EGO54037.1 - 0.14 12.2 1.5 0.75 9.8 0.4 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EGO54037.1 - 0.28 11.1 3.4 12 5.8 0.2 2.5 2 0 0 2 2 2 0 TrkA-N domain Ceramidase_alk PF04734.8 EGO54038.1 - 8e-279 926.1 0.0 9.1e-279 926.0 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Dynamin_N PF00350.18 EGO54039.1 - 6.9e-11 42.2 1.9 1.5e-10 41.1 0.1 2.5 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EGO54039.1 - 0.00022 21.1 0.0 0.076 12.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran PF00005.22 EGO54039.1 - 0.00034 20.9 2.0 0.0073 16.6 0.0 3.2 3 0 0 3 3 3 1 ABC transporter Voldacs PF03517.8 EGO54039.1 - 0.026 14.3 0.3 0.026 14.3 0.2 2.4 3 0 0 3 3 3 0 Regulator of volume decrease after cellular swelling NFRKB_winged PF14465.1 EGO54039.1 - 0.074 12.8 0.4 0.44 10.3 0.0 2.5 2 0 0 2 2 2 0 NFRKB Winged Helix-like AAA_17 PF13207.1 EGO54039.1 - 0.25 12.1 2.1 2.5 8.9 0.3 3.1 3 1 0 3 3 3 0 AAA domain VHS PF00790.14 EGO54041.1 - 4.9e-26 91.0 0.0 2.9e-25 88.5 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EGO54041.1 - 1.5e-10 40.9 1.8 3.2e-10 39.8 1.2 1.5 1 0 0 1 1 1 1 GAT domain Elongin_A PF06881.6 EGO54041.1 - 0.033 14.5 0.1 0.15 12.4 0.1 2.1 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Borrelia_orfA PF02414.10 EGO54041.1 - 0.098 11.7 3.1 0.14 11.2 2.1 1.2 1 0 0 1 1 1 0 Borrelia ORF-A Amidohydro_4 PF13147.1 EGO54042.1 - 2.5e-16 60.5 0.2 3.7e-07 30.4 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EGO54042.1 - 1.5e-09 37.9 0.1 1.7e-06 27.9 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EGO54042.1 - 2.6e-07 30.2 0.0 1.8e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGO54042.1 - 8.7e-05 22.2 0.0 0.00042 20.0 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Glyco_hydro_3 PF00933.16 EGO54043.1 - 3.1e-52 177.4 0.0 4.6e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_7 PF13508.1 EGO54043.1 - 0.007 16.4 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 EGO54043.1 - 0.018 14.6 0.1 0.056 12.9 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 EGO54043.1 - 0.057 13.4 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Glucosamine_iso PF01182.15 EGO54044.1 - 1.6e-24 86.7 0.0 3.2e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_2 PF03727.11 EGO54045.1 - 2.4e-31 108.8 0.0 6.1e-25 87.8 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EGO54045.1 - 6.4e-28 97.5 0.0 1.2e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Hexokinase NDT80_PhoG PF05224.7 EGO54046.1 - 4.9e-43 147.3 0.0 7.2e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Piwi PF02171.12 EGO54047.1 - 5e-66 222.7 0.0 7.4e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EGO54047.1 - 8.5e-12 44.5 0.0 1.8e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EGO54047.1 - 4.4e-08 32.3 0.0 1e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) DUF2014 PF09427.5 EGO54048.1 - 1.1e-116 388.5 4.8 1.6e-116 388.0 3.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EGO54048.1 - 5.5e-17 61.1 0.8 1.3e-16 60.0 0.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PBP1_TM PF14812.1 EGO54048.1 - 0.74 10.1 6.2 1.8 8.9 2.8 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HET PF06985.6 EGO54050.1 - 2.9e-26 92.2 0.0 5.7e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) E1-E2_ATPase PF00122.15 EGO54052.1 - 3.6e-57 193.0 1.6 3.6e-57 193.0 1.1 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGO54052.1 - 8.7e-43 145.9 6.5 8.7e-43 145.9 4.5 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGO54052.1 - 1.6e-29 103.8 0.2 3e-28 99.7 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO54052.1 - 2.6e-19 68.9 0.0 5.5e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGO54052.1 - 9.2e-17 61.8 0.0 1.9e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGO54052.1 - 1.7e-07 30.5 0.1 2.4e-05 23.7 0.0 3.8 4 0 0 4 4 4 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGO54052.1 - 4.8e-05 23.0 1.4 9e-05 22.1 0.6 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2976 PF11190.3 EGO54052.1 - 0.0099 15.3 8.9 0.088 12.3 0.3 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF2976) YjgP_YjgQ PF03739.9 EGO54052.1 - 0.088 11.5 7.4 0.01 14.5 1.6 2.0 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family DUF2207 PF09972.4 EGO54052.1 - 0.88 8.0 6.8 1.7 7.1 0.2 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF2142 PF09913.4 EGO54052.1 - 8.2 4.9 17.1 0.0095 14.6 2.3 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2142) zf-primase PF09329.6 EGO54053.1 - 1.2e-18 66.4 0.7 2.1e-18 65.6 0.5 1.4 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 EGO54053.1 - 0.0018 18.1 0.0 0.0049 16.6 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ANAPC15 PF15243.1 EGO54053.1 - 0.033 14.2 4.4 0.2 11.7 0.1 3.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 RNase_H2-Ydr279 PF09468.5 EGO54055.1 - 1.3e-99 333.2 0.1 1.3e-99 333.2 0.1 1.4 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) DASH_Duo1 PF08651.5 EGO54056.1 - 1.4e-31 107.8 0.3 2.1e-31 107.3 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 Peptidase_S30 PF01577.11 EGO54056.1 - 0.21 10.9 4.6 0.24 10.7 0.1 2.1 2 0 0 2 2 2 0 Potyvirus P1 protease Cwf_Cwc_15 PF04889.7 EGO54056.1 - 0.32 10.6 12.1 0.14 11.8 0.3 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NAM-associated PF14303.1 EGO54056.1 - 0.39 11.0 9.8 0.68 10.2 6.8 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF1682 PF07946.9 EGO54056.1 - 1.2 7.9 4.1 1.7 7.4 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Macoilin PF09726.4 EGO54056.1 - 1.6 6.8 11.2 2.7 6.1 7.8 1.2 1 0 0 1 1 1 0 Transmembrane protein FNIP_N PF14636.1 EGO54056.1 - 1.7 9.1 8.6 0.53 10.7 2.5 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus BRF1 PF07741.8 EGO54056.1 - 2.7 8.2 13.6 1.9 8.7 1.9 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain APC_CDC26 PF10471.4 EGO54056.1 - 5.2 7.8 15.4 9 7.1 5.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF3439 PF11921.3 EGO54057.1 - 0.0033 17.1 5.0 0.0082 15.8 3.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) SSP160 PF06933.6 EGO54057.1 - 4.2 5.2 11.6 7.8 4.3 8.1 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TTL PF03133.10 EGO54059.1 - 2.5e-53 180.9 0.0 3.9e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EGO54059.1 - 1.7e-40 138.4 0.0 3.1e-40 137.5 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE Glyco_trans_4_4 PF13579.1 EGO54059.1 - 0.019 15.1 1.0 0.034 14.2 0.7 1.5 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain DUF2457 PF10446.4 EGO54059.1 - 0.13 10.9 21.8 0.21 10.2 15.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 EGO54059.1 - 0.6 9.1 11.2 0.92 8.5 7.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.7 EGO54059.1 - 0.98 8.6 16.8 1.5 8.0 11.7 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EGO54059.1 - 4.3 5.1 19.1 8.5 4.1 13.2 1.4 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 EGO54059.1 - 6.3 4.5 7.9 12 3.5 5.5 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.6 EGO54059.1 - 8 4.4 8.1 13 3.7 5.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.5 EGO54059.1 - 8.7 5.2 14.2 15 4.5 9.8 1.3 1 0 0 1 1 1 0 BUD22 DHDPS PF00701.17 EGO54060.1 - 1.4e-13 50.0 0.0 2e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF1604 PF07713.8 EGO54062.1 - 3.3e-40 135.7 2.3 1.9e-39 133.2 0.8 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EGO54062.1 - 2.3e-06 27.2 2.2 2.3e-06 27.2 1.5 3.1 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.2 EGO54062.1 - 0.0019 18.0 1.3 0.013 15.3 0.1 2.9 2 1 0 2 2 2 1 DExH-box splicing factor binding site Pkinase PF00069.20 EGO54064.1 - 8.2e-71 238.1 0.0 1.3e-70 237.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO54064.1 - 4.2e-37 127.6 0.0 6.2e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EGO54064.1 - 1.5e-19 69.1 0.1 2.6e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EGO54064.1 - 6e-07 28.7 0.1 1.3e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGO54064.1 - 0.00025 20.1 0.0 0.00039 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO54064.1 - 0.00057 19.6 1.0 0.0023 17.6 0.7 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 EGO54064.1 - 0.0083 15.3 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 EGO54064.1 - 0.023 14.0 0.0 0.056 12.7 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EGO54064.1 - 0.023 14.0 0.1 0.059 12.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family DUF3357 PF11837.3 EGO54064.1 - 0.087 12.6 3.5 0.32 10.8 2.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Dicty_REP PF05086.7 EGO54064.1 - 6.2 4.4 11.4 0.2 9.4 2.8 1.9 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein HET PF06985.6 EGO54065.1 - 6.4e-26 91.1 0.3 1.1e-25 90.4 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Dna2 PF08696.6 EGO54066.1 - 3e-77 258.6 0.9 1.2e-76 256.6 0.1 2.1 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 EGO54066.1 - 4.2e-37 127.4 0.0 7.5e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.12 EGO54066.1 - 3.1e-09 36.9 0.2 1.9e-08 34.4 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 EGO54066.1 - 1e-05 25.0 0.0 2.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF911 PF06023.7 EGO54066.1 - 0.027 13.7 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF911) Gryzun PF07919.7 EGO54067.1 - 2.4e-116 389.2 5.2 3e-116 388.9 3.6 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EGO54067.1 - 3.9e-86 288.5 1.8 6.1e-83 278.0 1.7 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 EGO54067.1 - 0.16 11.7 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking LptE PF04390.7 EGO54067.1 - 0.22 11.2 0.0 0.59 9.8 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide-assembly Kelch_5 PF13854.1 EGO54068.1 - 3.5e-08 33.2 3.8 3.6e-07 29.9 0.1 3.8 4 0 0 4 4 4 1 Kelch motif CBM_10 PF02013.11 EGO54068.1 - 0.084 13.1 0.8 0.24 11.6 0.5 1.7 1 0 0 1 1 1 0 Cellulose or protein binding domain Kelch_6 PF13964.1 EGO54068.1 - 0.099 12.8 9.1 1.1 9.5 0.2 4.7 4 1 1 5 5 5 0 Kelch motif Kelch_3 PF13415.1 EGO54068.1 - 0.57 10.4 11.1 2.2 8.5 0.0 5.5 5 1 0 5 5 5 0 Galactose oxidase, central domain Kelch_4 PF13418.1 EGO54068.1 - 8.2 6.2 17.7 4.7 7.0 0.1 6.1 7 0 0 7 7 7 0 Galactose oxidase, central domain ESSS PF10183.4 EGO54070.1 - 1.6e-27 95.9 0.1 1.9e-27 95.7 0.1 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Aminotran_4 PF01063.14 EGO54071.1 - 2.1e-30 105.9 0.0 2.8e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV RNA_pol_I_A49 PF06870.7 EGO54071.1 - 0.16 10.4 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor Pkinase PF00069.20 EGO54072.1 - 4.9e-18 65.2 0.0 9.8e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO54072.1 - 4.6e-09 35.7 0.0 2.6e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase KRTAP PF11759.3 EGO54072.1 - 0.012 15.8 3.6 0.012 15.8 2.5 2.0 2 0 0 2 2 2 0 Keratin-associated matrix DUF3210 PF11489.3 EGO54073.1 - 3.8e-254 845.7 90.6 3.8e-254 845.7 62.8 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3210) NTF2 PF02136.15 EGO54074.1 - 2.6e-31 108.4 0.0 2.9e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Cg6151-P PF10233.4 EGO54075.1 - 1.9e-40 137.3 11.3 2.3e-40 137.1 7.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF1430 PF07242.6 EGO54075.1 - 0.43 10.6 7.3 0.1 12.6 2.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Dpy19 PF10034.4 EGO54075.1 - 1.1 7.3 4.9 1.2 7.1 3.4 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation PRA1 PF03208.14 EGO54075.1 - 8.9 5.6 9.7 14 4.9 6.6 1.4 1 1 0 1 1 1 0 PRA1 family protein Seipin PF06775.9 EGO54077.1 - 4.2e-65 219.0 0.0 5.4e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) FCH PF00611.18 EGO54078.1 - 2.6e-15 56.3 1.1 1.3e-14 54.1 0.7 2.3 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EGO54078.1 - 2.6e-13 49.1 0.0 5.5e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGO54078.1 - 1.1e-11 44.0 0.3 6.7e-11 41.6 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EGO54078.1 - 1.5e-11 43.5 0.0 1e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain DTHCT PF08070.6 EGO54078.1 - 0.0098 16.5 0.0 0.0098 16.5 0.0 3.0 3 0 0 3 3 3 1 DTHCT (NUC029) region UPF0029 PF01205.14 EGO54079.1 - 6.6e-27 93.3 0.0 1.9e-26 91.9 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Gp5_OB PF06714.6 EGO54079.1 - 0.058 13.4 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Gp5 N-terminal OB domain Methyltransf_23 PF13489.1 EGO54080.1 - 1.6e-13 50.7 0.1 7.6e-13 48.4 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO54080.1 - 8.3e-05 23.0 0.0 0.0037 17.7 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO54080.1 - 9.8e-05 22.7 0.0 0.46 11.0 0.0 3.4 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 EGO54080.1 - 0.00038 21.0 0.0 0.0039 17.7 0.0 2.5 2 2 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO54080.1 - 0.00066 18.8 0.0 0.063 12.3 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EGO54080.1 - 0.0022 17.5 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain EIID-AGA PF03613.9 EGO54080.1 - 0.083 11.8 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component TAF4 PF05236.9 EGO54081.1 - 0.032 13.5 2.6 0.052 12.8 1.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Sensor PF13796.1 EGO54083.1 - 0.32 10.5 2.8 0.41 10.2 2.0 1.2 1 0 0 1 1 1 0 Putative sensor Not1 PF04054.10 EGO54084.1 - 1.7e-123 412.2 0.0 3.6e-123 411.1 0.0 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EGO54084.1 - 1.2e-47 161.3 3.6 3.1e-47 159.9 2.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CorA PF01544.13 EGO54085.1 - 9.3e-10 38.0 9.3 6.4e-09 35.2 0.4 2.6 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein DUF676 PF05057.9 EGO54085.1 - 4.3e-07 29.4 0.0 1.2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Ni_hydr_CYTB PF01292.15 EGO54085.1 - 0.03 13.7 0.9 2.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 ETF_QO PF05187.8 EGO54086.1 - 1e-46 157.4 0.1 1.6e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EGO54086.1 - 2.2e-08 33.4 0.3 0.00024 20.1 0.1 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO54086.1 - 2.1e-07 30.8 0.0 5.7e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EGO54086.1 - 3.7e-06 26.2 0.0 7.7e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO54086.1 - 7.2e-05 21.8 0.7 0.0023 16.8 0.7 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EGO54086.1 - 0.00034 20.5 0.1 0.00064 19.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO54086.1 - 0.00051 19.2 0.0 0.007 15.4 0.1 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EGO54086.1 - 0.00064 18.3 0.3 0.00099 17.6 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EGO54086.1 - 0.00064 20.0 0.1 5.4 7.4 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGO54086.1 - 0.0008 18.1 0.1 0.075 11.6 0.1 2.4 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 EGO54086.1 - 0.0015 18.6 0.4 0.0055 16.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO54086.1 - 0.0015 17.6 0.2 0.003 16.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.2 EGO54086.1 - 0.0025 18.1 1.4 0.0072 16.6 1.0 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain NAD_binding_9 PF13454.1 EGO54086.1 - 0.0039 16.9 0.2 0.0095 15.7 0.1 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EGO54086.1 - 0.032 13.1 0.2 0.047 12.6 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_10 PF13237.1 EGO54086.1 - 0.084 12.6 0.9 0.18 11.6 0.6 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.17 EGO54086.1 - 0.11 11.2 0.4 0.19 10.5 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TBP PF00352.16 EGO54087.1 - 2e-70 232.2 0.1 3.4e-35 119.2 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EGO54087.1 - 0.00019 21.3 0.0 0.77 9.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 EGO54087.1 - 0.018 15.3 3.5 0.027 14.8 2.4 1.5 1 1 0 1 1 1 0 Ribonuclease (pollen allergen) DAO PF01266.19 EGO54088.1 - 1.3e-52 178.8 0.2 1.7e-52 178.5 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGO54088.1 - 7.3e-07 29.0 0.0 0.0082 15.9 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGO54088.1 - 5.3e-05 23.1 0.0 0.00023 21.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EGO54088.1 - 0.0042 16.0 0.0 0.017 14.0 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EGO54088.1 - 0.0059 15.2 0.0 1.1 7.7 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 EGO54088.1 - 0.0099 15.7 0.0 0.13 12.0 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 EGO54088.1 - 0.015 14.3 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Pyr_redox PF00070.22 EGO54088.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Surp PF01805.15 EGO54089.1 - 4.3e-17 61.5 0.0 1.1e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 Surp module RRM_6 PF14259.1 EGO54089.1 - 0.015 15.2 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TAF4 PF05236.9 EGO54089.1 - 0.08 12.2 12.0 0.75 9.0 0.7 2.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Copper-fist PF00649.13 EGO54090.1 - 8.5e-18 63.2 1.6 8.5e-18 63.2 1.1 1.8 2 0 0 2 2 2 1 Copper fist DNA binding domain Methyltransf_16 PF10294.4 EGO54092.1 - 2.5e-12 46.6 0.0 3.4e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGO54092.1 - 0.013 16.1 0.0 0.022 15.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EGO54092.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Zip PF02535.17 EGO54094.1 - 0.084 11.8 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter GRA6 PF05084.8 EGO54094.1 - 0.55 9.7 0.0 0.55 9.7 0.0 2.2 1 1 1 2 2 2 0 Granule antigen protein (GRA6) DUF4519 PF15012.1 EGO54094.1 - 1.3 8.9 3.4 2.7 7.9 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Radial_spoke PF04712.7 EGO54094.1 - 1.8 7.2 7.1 11 4.6 0.0 2.1 2 0 0 2 2 2 0 Radial spokehead-like protein OCD_Mu_crystall PF02423.10 EGO54095.1 - 3.5e-11 42.4 0.1 2.9e-05 22.9 0.0 3.4 3 1 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family CDC45 PF02724.9 EGO54095.1 - 0.042 11.8 4.9 0.063 11.3 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S16 PF00886.14 EGO54095.1 - 0.23 11.2 1.2 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S16 UPF0560 PF10577.4 EGO54095.1 - 4.9 5.2 11.0 7.3 4.7 7.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Pro_CA PF00484.14 EGO54096.1 - 3e-45 153.9 0.2 3.7e-45 153.6 0.2 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_5 PF12695.2 EGO54096.1 - 0.085 12.6 0.1 0.15 11.8 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 EGO54096.1 - 0.094 10.9 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Ribosomal_L7Ae PF01248.21 EGO54097.1 - 3.6e-21 74.4 1.0 3.6e-21 74.4 0.7 1.6 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EGO54097.1 - 0.0077 16.0 0.2 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 CLPTM1 PF05602.7 EGO54097.1 - 0.1 11.2 0.2 0.14 10.8 0.2 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) ATP_bind_3 PF01171.15 EGO54098.1 - 4.5e-18 65.3 0.0 7.1e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EGO54098.1 - 0.00071 19.8 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 EGO54098.1 - 0.00074 18.8 1.2 0.00074 18.8 0.8 3.3 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.11 EGO54098.1 - 0.016 13.8 0.0 0.027 13.0 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase TSP9 PF11493.3 EGO54098.1 - 0.12 12.9 1.5 0.34 11.4 1.0 1.7 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 zf-UBR PF02207.15 EGO54098.1 - 0.83 9.4 7.2 0.5 10.1 0.5 2.7 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) MOZ_SAS PF01853.13 EGO54100.1 - 8.2e-81 269.7 0.4 1.2e-80 269.2 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family ENTH PF01417.15 EGO54101.1 - 5.4e-49 165.2 0.0 8.2e-49 164.6 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EGO54101.1 - 0.027 13.1 0.0 0.052 12.2 0.0 1.5 1 0 0 1 1 1 0 ANTH domain DUF4264 PF14084.1 EGO54101.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) UIM PF02809.15 EGO54101.1 - 0.12 12.0 2.6 0.15 11.7 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif Nup96 PF12110.3 EGO54102.1 - 3.1e-64 216.8 0.0 4.5e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EGO54102.1 - 7.6e-43 145.7 0.0 1.2e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EGO54102.1 - 3e-19 69.3 369.1 9.9e-09 35.4 28.0 10.3 3 2 5 8 8 8 3 Nucleoporin FG repeat region F-box-like PF12937.2 EGO54103.1 - 5.1e-09 35.7 0.3 5.1e-09 35.7 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGO54103.1 - 2e-06 27.2 0.2 4e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 F-box domain SNF2_N PF00176.18 EGO54104.1 - 2.2e-74 249.9 0.0 8.8e-74 247.9 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO54104.1 - 6.7e-10 38.6 0.0 1.8e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 EGO54104.1 - 0.13 11.6 4.6 0.21 10.9 0.0 2.4 2 0 0 2 2 2 0 DEAD_2 E6 PF00518.12 EGO54104.1 - 0.27 11.5 3.7 3.7 7.9 1.3 2.6 2 0 0 2 2 2 0 Early Protein (E6) TRAUB PF08164.7 EGO54105.1 - 5.7e-32 109.6 0.2 2e-31 107.9 0.1 2.1 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EGO54105.1 - 3.3e-30 104.9 0.7 3.3e-30 104.9 0.5 2.9 3 2 1 4 4 4 1 Apoptosis antagonizing transcription factor Ran-binding PF05508.6 EGO54106.1 - 8.1e-108 359.8 0.0 1e-107 359.5 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.22 EGO54107.1 - 5.4e-44 149.8 0.0 9.2e-44 149.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGO54107.1 - 9.1e-21 73.8 0.0 2.7e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGO54107.1 - 2.7e-07 30.5 0.2 7.5e-07 29.1 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGO54107.1 - 4.5e-05 23.3 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EGO54107.1 - 1.1 7.8 3.1 0.39 9.3 0.1 1.7 2 0 0 2 2 2 0 G-protein alpha subunit adh_short PF00106.20 EGO54108.1 - 1.7e-18 67.1 0.6 2.8e-16 59.8 0.4 3.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO54108.1 - 4.5e-14 52.8 0.0 1e-11 45.0 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO54108.1 - 8.5e-10 38.5 0.2 3e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EGO54108.1 - 0.055 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EGO54108.1 - 0.057 13.5 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UCH_1 PF13423.1 EGO54109.1 - 2.3e-51 175.0 0.0 3.8e-51 174.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Mito_carr PF00153.22 EGO54109.1 - 2.9e-51 171.1 6.8 1.8e-19 69.2 0.1 4.3 4 0 0 4 4 4 3 Mitochondrial carrier protein RNase_T PF00929.19 EGO54109.1 - 5.5e-24 85.3 0.0 1.3e-23 84.0 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EGO54109.1 - 1.5e-07 30.8 0.0 6.9e-07 28.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase LBR_tudor PF09465.5 EGO54111.1 - 0.00095 18.7 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain DUF4537 PF15057.1 EGO54111.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) DUF1325 PF07039.6 EGO54111.1 - 0.12 11.9 0.2 0.26 10.8 0.2 1.5 1 0 0 1 1 1 0 SGF29 tudor-like domain Fis1_TPR_C PF14853.1 EGO54111.1 - 0.13 12.1 0.4 0.24 11.2 0.3 1.3 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Syntaxin-6_N PF09177.6 EGO54111.1 - 0.15 12.4 0.7 0.3 11.5 0.5 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal SOG2 PF10428.4 EGO54111.1 - 0.19 10.3 5.3 0.25 9.9 3.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TCO89 PF10452.4 EGO54112.1 - 0.00029 19.8 38.0 0.0036 16.2 26.2 2.3 1 1 0 1 1 1 1 TORC1 subunit TCO89 Thiolase_N PF00108.18 EGO54113.1 - 4.1e-79 265.2 2.5 6.4e-79 264.6 1.8 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGO54113.1 - 1.5e-44 150.3 0.2 3e-44 149.4 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 EGO54113.1 - 0.013 15.5 0.0 0.051 13.5 0.0 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 EGO54113.1 - 0.068 12.6 6.2 0.073 12.5 1.8 2.4 2 1 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain FBPase PF00316.15 EGO54114.1 - 1.7e-125 418.1 0.2 1.9e-125 417.9 0.1 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EGO54114.1 - 0.061 12.6 0.0 0.25 10.5 0.0 1.9 2 0 0 2 2 2 0 Inositol monophosphatase family NdhM PF10664.4 EGO54114.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M Glyco_hydro_92 PF07971.7 EGO54115.1 - 7.6e-150 499.8 0.8 1.1e-135 453.1 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 92 RRM_1 PF00076.17 EGO54116.1 - 9.4e-82 268.6 7.3 9.1e-22 76.4 0.4 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO54116.1 - 2.3e-56 187.6 2.4 3.7e-15 55.6 0.0 5.8 6 0 0 6 6 6 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO54116.1 - 4e-41 138.6 0.1 8.5e-10 38.3 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EGO54116.1 - 5.3e-29 99.6 0.6 2.8e-28 97.3 0.4 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EGO54116.1 - 2.8e-05 23.8 0.7 7.4 6.4 0.0 4.7 4 1 0 4 4 4 2 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 EGO54116.1 - 0.00012 22.2 2.2 3 8.1 0.0 4.4 4 0 0 4 4 4 2 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 EGO54116.1 - 0.00071 19.2 2.5 4.1 7.2 0.1 3.5 3 0 0 3 3 3 2 Limkain b1 YflT PF11181.3 EGO54116.1 - 0.004 17.2 4.6 0.097 12.8 0.1 3.3 3 0 0 3 3 3 1 Heat induced stress protein YflT OB_RNB PF08206.6 EGO54116.1 - 0.04 13.4 1.6 5.3 6.6 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Draxin PF15550.1 EGO54116.1 - 0.78 9.3 8.1 0.3 10.7 3.8 1.6 2 0 0 2 2 2 0 Draxin HECT PF00632.20 EGO54117.1 - 2.6e-84 283.0 0.0 4.1e-84 282.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Chal_sti_synt_N PF00195.14 EGO54118.1 - 1.6e-21 76.5 0.1 2.4e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 EGO54118.1 - 4e-20 72.2 0.0 7.7e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.7 EGO54118.1 - 2.6e-05 23.4 0.0 3.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 EGO54118.1 - 0.00055 19.9 0.0 0.0015 18.4 0.0 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 EGO54118.1 - 0.0011 18.6 0.1 0.0028 17.2 0.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PEX11 PF05648.9 EGO54119.1 - 1.4e-75 253.3 0.5 1.6e-75 253.1 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Spore_YhaL PF14147.1 EGO54119.1 - 0.071 12.5 0.4 0.14 11.6 0.3 1.4 1 0 0 1 1 1 0 Sporulation protein YhaL NMO PF03060.10 EGO54120.1 - 9.6e-65 218.8 0.3 1.6e-64 218.1 0.2 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGO54120.1 - 3.4e-12 45.9 0.0 4.6e-06 25.7 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGO54120.1 - 0.0058 15.5 0.1 0.01 14.7 0.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EGO54120.1 - 0.023 13.9 0.1 0.059 12.6 0.0 1.7 1 0 0 1 1 1 0 Histidine biosynthesis protein dsrm PF00035.20 EGO54122.1 - 1.7e-06 28.5 0.0 2.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EGO54122.1 - 0.001 19.3 0.1 0.0026 18.0 0.1 1.7 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 WxL PF13731.1 EGO54122.1 - 0.14 11.9 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 WxL domain surface cell wall-binding Ribosomal_S7 PF00177.16 EGO54123.1 - 9.5e-26 90.1 0.0 4.6e-25 87.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e Usp PF00582.21 EGO54124.1 - 2.1e-22 79.8 7.7 7.2e-15 55.4 0.2 3.7 5 0 0 5 5 5 2 Universal stress protein family Sugar_tr PF00083.19 EGO54126.1 - 8.1e-35 120.2 30.4 4.5e-20 71.6 7.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGO54126.1 - 9.3e-18 64.0 45.1 4.4e-11 42.0 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF843 PF05814.6 EGO54126.1 - 0.16 11.8 0.7 0.51 10.1 0.1 2.1 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) PTPA PF03095.10 EGO54127.1 - 2.6e-105 351.8 0.0 8.3e-105 350.2 0.0 1.8 1 1 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Mito_fiss_reg PF05308.6 EGO54127.1 - 0.049 12.9 6.2 0.16 11.2 4.3 1.8 1 0 0 1 1 1 0 Mitochondrial fission regulator Actino_peptide PF14408.1 EGO54127.1 - 0.19 11.6 6.8 3.9 7.4 1.8 2.5 2 0 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes DUF2360 PF10152.4 EGO54128.1 - 0.73 10.1 3.4 4.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Pkinase PF00069.20 EGO54129.1 - 8.7e-06 25.0 0.0 6.1e-05 22.2 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Ribosomal_60s PF00428.14 EGO54129.1 - 0.004 17.5 0.7 0.012 15.9 0.5 1.8 1 0 0 1 1 1 1 60s Acidic ribosomal protein WEMBL PF05701.6 EGO54130.1 - 0.0094 14.4 3.5 0.022 13.2 2.4 1.5 1 0 0 1 1 1 1 Weak chloroplast movement under blue light AT_hook PF02178.14 EGO54130.1 - 0.077 12.7 6.2 0.3 10.8 4.3 2.1 1 0 0 1 1 1 0 AT hook motif DUF21 PF01595.15 EGO54131.1 - 3.5e-32 111.1 0.0 5.4e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EGO54131.1 - 2.4e-06 27.2 1.3 0.0048 16.6 0.0 3.4 4 0 0 4 4 4 2 CBS domain T4_Gp59_C PF08994.5 EGO54131.1 - 0.2 11.8 0.0 0.45 10.7 0.0 1.5 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term Glyoxalase PF00903.20 EGO54132.1 - 2.5e-38 130.9 0.1 6.1e-18 65.0 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGO54132.1 - 8.5e-31 106.7 0.1 6.9e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EGO54132.1 - 1.4e-16 60.4 0.0 7.6e-07 29.1 0.0 3.3 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EGO54132.1 - 2.1e-05 24.4 0.0 0.41 10.5 0.0 3.0 1 1 2 3 3 3 3 Glyoxalase-like domain CppA_N PF14506.1 EGO54132.1 - 0.018 14.6 0.1 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 CppA N-terminal DUF3565 PF12088.3 EGO54133.1 - 0.16 11.7 0.3 0.38 10.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3565) COX15-CtaA PF02628.10 EGO54134.1 - 3.3e-95 318.4 11.0 4.4e-95 318.0 7.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF2611 PF11022.3 EGO54134.1 - 0.3 11.1 1.2 0.56 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) Cation_efflux PF01545.16 EGO54135.1 - 1.6e-21 76.6 11.6 6.1e-14 51.7 0.6 2.1 2 0 0 2 2 2 2 Cation efflux family Zip PF02535.17 EGO54136.1 - 1.1e-47 162.5 8.8 9.8e-47 159.4 6.1 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Mt_ATP-synt_B PF05405.9 EGO54137.1 - 0.022 14.2 7.1 0.035 13.5 4.9 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) PSCyt1 PF07635.6 EGO54137.1 - 0.09 13.1 0.3 0.31 11.3 0.1 1.9 1 1 1 2 2 2 0 Planctomycete cytochrome C V_ATPase_I PF01496.14 EGO54137.1 - 5.9 4.6 10.0 6.5 4.4 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EGO54137.1 - 6.5 6.3 8.7 8.6 5.9 6.0 1.3 1 0 0 1 1 1 0 IncA protein MIP-T3 PF10243.4 EGO54137.1 - 9.7 4.5 39.5 12 4.2 27.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DZR PF12773.2 EGO54138.1 - 0.64 9.8 3.4 15 5.4 2.4 2.5 1 1 1 2 2 2 0 Double zinc ribbon Rad4 PF03835.10 EGO54139.1 - 1.1e-25 89.7 0.0 1.1e-25 89.7 0.0 2.5 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EGO54139.1 - 9.7e-23 79.6 0.1 1.8e-22 78.8 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EGO54139.1 - 1.2e-22 79.1 0.0 3.4e-22 77.7 0.0 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EGO54139.1 - 3.7e-11 43.1 0.0 3.7e-11 43.1 0.0 2.9 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EGO54139.1 - 3.4e-05 24.0 0.0 0.0018 18.4 0.1 3.1 2 1 0 2 2 2 1 Transglutaminase-like superfamily YqfQ PF14181.1 EGO54139.1 - 0.38 10.7 8.5 1.7 8.6 5.9 2.1 1 0 0 1 1 1 0 YqfQ-like protein ADH_N PF08240.7 EGO54140.1 - 2e-23 82.2 7.0 2e-23 82.2 4.8 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO54140.1 - 1.9e-18 66.2 0.0 6e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGO54140.1 - 0.00025 20.2 0.1 0.00045 19.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 EGO54140.1 - 0.0044 17.9 0.0 0.0086 16.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SET PF00856.23 EGO54142.1 - 4.7e-05 23.7 0.0 0.00019 21.8 0.0 2.0 1 1 0 1 1 1 1 SET domain HSBP1 PF06825.7 EGO54143.1 - 3.1e-06 26.6 0.0 1.4 8.5 0.0 5.6 3 1 1 4 4 4 2 Heat shock factor binding protein 1 CENP-F_leu_zip PF10473.4 EGO54143.1 - 0.00087 19.1 24.8 0.00087 19.1 17.2 12.1 3 2 9 12 12 12 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 EGO54143.1 - 0.0043 16.8 32.9 0.0043 16.8 22.8 11.8 1 1 10 11 11 11 2 Tropomyosin like Fez1 PF06818.10 EGO54143.1 - 0.0061 16.6 19.6 0.0061 16.6 13.6 9.3 1 1 8 9 9 9 1 Fez1 Seryl_tRNA_N PF02403.17 EGO54143.1 - 0.01 15.8 11.8 0.01 15.8 8.2 16.0 2 1 14 17 17 17 0 Seryl-tRNA synthetase N-terminal domain Filament PF00038.16 EGO54143.1 - 0.017 14.5 209.3 0.29 10.5 24.0 7.0 1 1 5 6 6 6 0 Intermediate filament protein Reo_sigmaC PF04582.7 EGO54143.1 - 0.36 9.9 94.9 0.0057 15.8 2.0 8.4 1 1 7 8 8 8 0 Reovirus sigma C capsid protein Zn_clus PF00172.13 EGO54144.1 - 6e-10 38.8 12.3 9.6e-10 38.2 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Copper-fist PF00649.13 EGO54145.1 - 3.7e-22 77.2 2.6 3.7e-22 77.2 1.8 4.1 1 1 2 3 3 3 2 Copper fist DNA binding domain ApbA PF02558.11 EGO54148.1 - 8e-31 106.5 0.0 1.1e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EGO54148.1 - 4.4e-25 88.1 0.0 7.6e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pyr_redox PF00070.22 EGO54148.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PHY PF00360.15 EGO54151.1 - 1e-27 96.4 0.0 2.1e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 EGO54151.1 - 6.1e-20 70.9 0.3 1.2e-19 70.0 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 EGO54151.1 - 8e-17 61.7 0.1 3.9e-16 59.5 0.0 2.3 3 0 0 3 3 3 1 GAF domain Response_reg PF00072.19 EGO54151.1 - 8.7e-17 61.1 0.2 1.4e-15 57.3 0.0 2.8 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EGO54151.1 - 5.4e-13 48.7 0.7 1.6e-12 47.2 0.5 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 EGO54151.1 - 1.6e-07 31.7 0.0 5.3e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.1 EGO54151.1 - 0.062 12.9 0.6 0.15 11.7 0.1 1.9 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EGO54151.1 - 0.066 13.5 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.6 EGO54151.1 - 0.1 12.7 0.0 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 PAS fold HET PF06985.6 EGO54152.1 - 4.9e-16 59.1 0.0 8.1e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mito_carr PF00153.22 EGO54155.1 - 2.6e-56 187.2 1.6 1.2e-19 69.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EGO54155.1 - 0.0067 16.4 1.0 0.023 14.7 0.1 2.4 2 2 1 3 3 3 1 Tim17/Tim22/Tim23/Pmp24 family RCC1 PF00415.13 EGO54156.1 - 3.4e-22 78.3 0.2 7.2e-06 26.1 0.0 5.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EGO54156.1 - 4.9e-11 42.6 0.0 9.5e-10 38.4 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain Ank_4 PF13637.1 EGO54156.1 - 2.7e-10 40.4 0.2 8.8e-10 38.8 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.1 EGO54156.1 - 7.2e-07 28.6 0.2 7.2e-07 28.6 0.1 3.8 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 EGO54156.1 - 6.1e-06 25.9 0.4 0.2 12.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EGO54156.1 - 0.0001 22.5 0.1 0.00024 21.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGO54156.1 - 0.03 14.5 0.1 0.19 12.0 0.0 2.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.25 EGO54156.1 - 0.033 14.0 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat ATG13 PF10033.4 EGO54157.1 - 5.8e-70 235.3 0.0 1.1e-69 234.3 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 13 VHS PF00790.14 EGO54158.1 - 1.2e-36 125.4 0.4 2.5e-36 124.4 0.3 1.6 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 EGO54158.1 - 2.7e-16 58.8 0.2 4.8e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO54158.1 - 1.6e-15 56.2 0.1 3.2e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGO54158.1 - 2.2e-13 49.4 0.0 4.3e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 EGO54158.1 - 0.04 13.4 7.7 0.096 12.3 5.3 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif GAT PF03127.9 EGO54158.1 - 0.063 13.2 1.5 0.14 12.1 0.5 1.9 2 0 0 2 2 2 0 GAT domain DUF4220 PF13968.1 EGO54158.1 - 0.52 9.3 1.6 0.56 9.2 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) ORC6 PF05460.8 EGO54159.1 - 0.19 10.7 8.5 0.24 10.4 5.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) eIF3_subunit PF08597.5 EGO54159.1 - 0.42 10.1 24.4 0.87 9.1 12.5 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Pap_E4 PF02711.9 EGO54159.1 - 1.7 9.5 5.8 4.1 8.3 1.4 2.6 2 1 0 2 2 2 0 E4 protein Presenilin PF01080.12 EGO54159.1 - 1.8 7.2 3.9 2.6 6.7 2.7 1.2 1 1 0 1 1 1 0 Presenilin YqfQ PF14181.1 EGO54159.1 - 1.9 8.5 25.2 5.5 6.9 12.9 2.1 2 0 0 2 2 2 0 YqfQ-like protein CWC25 PF12542.3 EGO54159.1 - 2.3 8.7 22.4 0.66 10.4 10.3 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing factor Merozoite_SPAM PF07133.6 EGO54159.1 - 2.9 7.7 30.9 0.13 12.1 16.8 1.9 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) DUF1764 PF08576.5 EGO54159.1 - 3.4 8.5 21.4 3.6 8.4 9.5 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) TRAP_alpha PF03896.11 EGO54159.1 - 3.5 6.5 12.0 0.51 9.2 5.3 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SR-25 PF10500.4 EGO54159.1 - 3.9 6.8 30.0 3.5 7.0 1.1 2.3 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3678 PF12435.3 EGO54160.1 - 4.8 6.8 7.6 9.7 5.8 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) DUF2461 PF09365.5 EGO54162.1 - 3.6e-69 232.3 0.0 5.1e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) eIF-3c_N PF05470.7 EGO54162.1 - 0.0079 14.3 0.3 0.0088 14.1 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.9 EGO54162.1 - 0.064 11.2 12.3 0.069 11.1 7.9 1.4 1 1 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 EGO54162.1 - 0.16 10.0 4.4 0.24 9.4 3.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 EGO54162.1 - 0.91 7.9 15.7 1.5 7.2 10.9 1.3 1 0 0 1 1 1 0 Daxx Family Trypan_PARP PF05887.6 EGO54162.1 - 1 9.2 11.4 2 8.2 7.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_Ag35 PF03286.9 EGO54162.1 - 1.5 8.3 15.2 2.5 7.5 10.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BUD22 PF09073.5 EGO54162.1 - 8.2 5.3 21.8 12 4.7 15.1 1.2 1 0 0 1 1 1 0 BUD22 BTV_NS2 PF04514.7 EGO54162.1 - 9.1 5.0 15.9 13 4.5 11.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Pectate_lyase_3 PF12708.2 EGO54163.1 - 1.3e-86 290.3 27.8 6.2e-71 239.0 6.4 3.4 3 1 1 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EGO54163.1 - 8.1e-06 25.2 0.9 0.033 13.6 0.1 2.5 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 EGO54163.1 - 5.3 6.7 18.1 0.073 12.8 5.7 2.9 3 0 0 3 3 3 0 Right handed beta helix region Fungal_trans PF04082.13 EGO54164.1 - 2.7e-08 32.9 0.4 0.0057 15.5 0.1 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain NIR_SIR PF01077.17 EGO54164.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain Cyclin_N PF00134.18 EGO54165.1 - 6.5e-14 51.5 0.0 1.2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EGO54165.1 - 1.2e-10 41.9 0.2 3.8e-10 40.3 0.2 1.7 1 1 0 1 1 1 1 Cyclin MRI PF15325.1 EGO54165.1 - 1.2 10.1 5.4 1 10.3 2.6 1.7 2 0 0 2 2 2 0 Modulator of retrovirus infection Pkinase PF00069.20 EGO54169.1 - 4.9e-72 242.1 0.0 5.9e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO54169.1 - 3e-31 108.4 0.0 3.8e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO54169.1 - 0.0018 17.2 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO54169.1 - 0.0047 16.6 0.0 0.012 15.3 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGO54169.1 - 0.023 13.5 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 2OG-FeII_Oxy_2 PF13532.1 EGO54170.1 - 4.3e-31 108.2 0.0 7.9e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EGO54170.1 - 0.071 13.6 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF3329 PF11808.3 EGO54173.1 - 0.056 13.5 0.1 0.056 13.5 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3329) DUF1049 PF06305.6 EGO54173.1 - 0.094 12.2 0.2 0.33 10.4 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) 2-Hacid_dh_C PF02826.14 EGO54174.1 - 5.6e-44 149.3 0.0 7.2e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGO54174.1 - 6.3e-06 25.6 0.0 2.3e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 EGO54174.1 - 0.016 15.5 0.0 0.036 14.3 0.0 1.6 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.1 EGO54174.1 - 0.02 15.1 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 EGO54174.1 - 0.057 12.9 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Acetyltransf_2 PF00797.12 EGO54175.1 - 5.3e-45 153.8 0.4 2e-44 151.9 0.3 1.8 1 1 0 1 1 1 1 N-acetyltransferase DUF427 PF04248.7 EGO54175.1 - 0.077 12.6 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF427) SGL PF08450.7 EGO54176.1 - 3.4e-06 26.6 0.1 0.00015 21.2 0.0 2.3 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region GSDH PF07995.6 EGO54176.1 - 0.00058 19.0 4.0 0.0073 15.4 1.2 3.1 1 1 1 2 2 2 1 Glucose / Sorbosone dehydrogenase RCC1_2 PF13540.1 EGO54176.1 - 0.012 15.2 1.8 1.6 8.4 0.3 3.1 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Lipoprotein_15 PF03640.10 EGO54176.1 - 0.06 12.7 1.5 0.16 11.4 0.1 2.5 2 0 0 2 2 2 0 Secreted repeat of unknown function Lactonase PF10282.4 EGO54176.1 - 0.06 12.4 0.1 0.79 8.7 0.0 2.6 2 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller DUF4448 PF14610.1 EGO54177.1 - 1e-30 106.6 0.0 2.3e-30 105.4 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Cwf_Cwc_15 PF04889.7 EGO54177.1 - 1.3 8.6 4.9 2 8.0 3.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.7 EGO54177.1 - 1.8 7.7 9.9 2.6 7.2 6.8 1.1 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EGO54177.1 - 5.7 6.4 7.8 10 5.6 5.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin Exo_endo_phos PF03372.18 EGO54179.1 - 1.4e-13 51.3 0.0 2.1e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EGO54179.1 - 0.022 14.3 0.4 0.59 9.7 0.3 2.5 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Adenylsucc_synt PF00709.16 EGO54180.1 - 3.2e-157 523.5 0.0 3.6e-157 523.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF3716 PF12511.3 EGO54181.1 - 7.4e-14 51.0 2.4 1.2e-13 50.4 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) RXT2_N PF08595.6 EGO54181.1 - 0.011 15.5 3.1 0.023 14.4 2.2 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal RNA_pol_3_Rpc31 PF11705.3 EGO54181.1 - 0.11 12.4 9.0 0.18 11.7 6.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Phage_sheath_1 PF04984.9 EGO54181.1 - 0.12 10.8 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Phage tail sheath protein NOA36 PF06524.7 EGO54181.1 - 0.32 10.2 7.5 0.46 9.6 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EGO54181.1 - 0.85 9.1 12.0 1.7 8.1 8.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 EGO54181.1 - 1.3 6.8 11.9 1.6 6.5 8.2 1.1 1 0 0 1 1 1 0 Nop14-like family S-antigen PF05756.6 EGO54181.1 - 2.6 8.0 11.2 5.4 7.0 7.7 1.5 1 0 0 1 1 1 0 S-antigen protein TRAP_alpha PF03896.11 EGO54181.1 - 3.5 6.5 9.1 6.2 5.7 6.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 EGO54181.1 - 5.2 4.9 8.6 8 4.3 6.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_RNA_Pol_19 PF05320.7 EGO54181.1 - 8.4 6.1 8.6 18 5.0 3.4 2.3 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit BSP_II PF05432.6 EGO54181.1 - 9.3 5.4 15.3 14 4.8 10.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Pectate_lyase_3 PF12708.2 EGO54182.1 - 3.3e-78 262.8 32.2 1.2e-65 221.7 5.1 4.6 4 1 0 5 5 5 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EGO54182.1 - 6e-05 22.4 4.7 0.06 12.8 0.3 3.1 2 1 1 3 3 3 2 N terminal extension of bacteriophage endosialidase Mucin PF01456.12 EGO54182.1 - 2 8.1 40.8 0.11 12.2 24.2 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Dicty_REP PF05086.7 EGO54182.1 - 7.2 4.2 4.5 11 3.6 3.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nuc_sug_transp PF04142.10 EGO54183.1 - 4e-77 258.6 7.0 6.5e-77 257.9 4.8 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EGO54183.1 - 1.1e-10 41.0 10.5 1.6e-07 30.5 1.4 2.5 2 1 1 3 3 3 2 UAA transporter family TPT PF03151.11 EGO54183.1 - 2.3e-08 33.8 21.3 0.00018 21.1 1.3 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EGO54183.1 - 1.8e-05 24.9 10.3 0.0012 19.0 0.4 2.6 2 0 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 EGO54183.1 - 1.8e-05 24.7 25.5 5e-05 23.3 3.1 2.9 3 1 0 3 3 3 2 EamA-like transporter family UPF0146 PF03686.8 EGO54183.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Sec63 PF02889.11 EGO54185.1 - 2.9e-40 138.4 0.0 4.5e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EGO54185.1 - 4.6e-27 94.5 0.0 1.1e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO54185.1 - 7e-10 38.6 0.0 1.3e-08 34.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO54185.1 - 5.6e-08 32.8 0.6 1.1e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EGO54185.1 - 0.0018 18.3 0.0 0.006 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EGO54185.1 - 0.0032 17.6 0.0 0.0087 16.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cdd1 PF11731.3 EGO54185.1 - 0.018 14.9 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus TfoX_C PF04994.8 EGO54185.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 TfoX C-terminal domain Helicase_RecD PF05127.9 EGO54185.1 - 0.057 13.0 0.3 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Helicase AAA_19 PF13245.1 EGO54185.1 - 0.084 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain GFO_IDH_MocA PF01408.17 EGO54186.1 - 6.4e-20 71.8 0.5 1.1e-19 71.0 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGO54186.1 - 0.00053 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EGO54186.1 - 0.034 14.4 0.0 0.094 13.0 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.11 EGO54187.1 - 9.2e-30 103.5 23.5 9.2e-30 103.5 16.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1077 PF06417.7 EGO54188.1 - 0.039 13.2 0.0 0.12 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) IBV_3C PF03620.8 EGO54188.1 - 0.11 12.4 2.3 0.28 11.0 0.1 2.3 2 0 0 2 2 2 0 IBV 3C protein GMC_oxred_N PF00732.14 EGO54190.1 - 7e-59 199.3 0.0 8.8e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO54190.1 - 3.9e-32 111.5 0.0 6.1e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EGO54190.1 - 5.8e-06 25.4 0.2 0.001 18.0 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO54190.1 - 5.5e-05 23.1 0.1 0.00012 22.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO54190.1 - 8.7e-05 21.5 0.0 0.017 13.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EGO54190.1 - 0.00013 20.9 0.1 0.00021 20.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EGO54190.1 - 0.0082 16.0 0.0 0.022 14.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO54190.1 - 0.059 13.7 0.1 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO54190.1 - 0.073 11.5 0.1 0.14 10.5 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein Mem_trans PF03547.13 EGO54191.1 - 1.9e-24 85.7 1.8 2.2e-24 85.4 1.2 1.1 1 0 0 1 1 1 1 Membrane transport protein SEEEED PF14797.1 EGO54191.1 - 0.065 13.3 9.6 0.092 12.8 6.7 1.1 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex DUF2463 PF09591.5 EGO54191.1 - 0.12 11.9 4.0 0.13 11.8 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) TauD PF02668.11 EGO54192.1 - 1.7e-43 149.1 0.1 2.3e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Carb_anhydrase PF00194.16 EGO54193.1 - 2.8e-17 62.5 0.1 5.2e-09 35.4 0.0 2.4 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase HEAT_2 PF13646.1 EGO54195.1 - 1.3e-14 54.2 8.8 0.024 14.8 0.3 8.2 5 2 2 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 EGO54195.1 - 5.6e-14 52.1 13.2 8.1e-06 26.1 0.0 10.1 8 3 5 13 13 13 4 HEAT-like repeat HEAT PF02985.17 EGO54195.1 - 1.5e-13 49.5 6.4 0.0034 17.3 0.0 8.6 9 0 0 9 9 9 3 HEAT repeat IBN_N PF03810.14 EGO54195.1 - 1e-08 34.9 0.4 9.9e-08 31.7 0.0 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EGO54195.1 - 4.5e-08 33.3 0.0 0.042 14.2 0.0 4.4 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EGO54195.1 - 1.5e-06 27.7 0.8 0.0065 15.8 0.0 5.1 6 1 1 7 7 7 1 CLASP N terminal Arm PF00514.18 EGO54195.1 - 4.3e-06 26.3 3.9 0.052 13.3 0.0 7.0 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat ParcG PF10274.4 EGO54195.1 - 1.2e-05 25.3 1.1 3.8 7.3 0.0 4.4 4 1 1 5 5 5 3 Parkin co-regulated protein Cnd1 PF12717.2 EGO54195.1 - 0.0019 18.1 0.1 3.9 7.2 0.0 3.6 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF577 PF04510.7 EGO54195.1 - 0.0021 17.7 0.1 0.011 15.3 0.0 2.4 1 0 0 1 1 1 1 Family of unknown function (DUF577) TIP120 PF08623.5 EGO54195.1 - 0.0026 17.3 0.1 0.057 12.9 0.0 3.1 2 1 1 3 3 3 1 TATA-binding protein interacting (TIP20) UME PF08064.8 EGO54195.1 - 0.0076 16.1 0.0 13 5.7 0.0 5.2 5 1 1 6 6 6 0 UME (NUC010) domain DUF2435 PF10363.4 EGO54195.1 - 0.0079 16.0 0.9 5.7 6.9 0.0 4.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) Adaptin_N PF01602.15 EGO54195.1 - 0.023 13.0 6.8 0.15 10.3 0.0 4.1 3 2 2 5 5 5 0 Adaptin N terminal region Proteasom_PSMB PF10508.4 EGO54195.1 - 0.026 12.8 1.2 0.61 8.2 0.1 2.8 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit RTA1 PF04479.8 EGO54196.1 - 3.5e-54 183.6 9.5 4.6e-54 183.2 6.6 1.1 1 0 0 1 1 1 1 RTA1 like protein TT_ORF2 PF02957.10 EGO54197.1 - 0.14 12.8 3.1 0.26 11.9 0.3 2.7 3 0 0 3 3 3 0 TT viral ORF2 DUF4188 PF13826.1 EGO54198.1 - 1.2e-31 109.2 0.3 1.8e-31 108.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) THRAP3_BCLAF1 PF15440.1 EGO54199.1 - 0.11 11.1 28.5 0.16 10.5 19.8 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family TFIIA PF03153.8 EGO54199.1 - 0.13 12.1 23.9 0.019 14.9 14.2 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit IncA PF04156.9 EGO54199.1 - 9.9 5.7 6.7 17 4.9 4.6 1.4 1 0 0 1 1 1 0 IncA protein LUC7 PF03194.10 EGO54200.1 - 8e-70 235.2 0.4 9.9e-70 234.9 0.2 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF3450 PF11932.3 EGO54200.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Gpi16 PF04113.9 EGO54201.1 - 5.1e-256 850.1 0.0 6.4e-256 849.8 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component FUSC PF04632.7 EGO54201.1 - 0.054 11.9 0.0 0.073 11.5 0.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FAD_binding_3 PF01494.14 EGO54202.1 - 5e-14 52.1 0.0 8.6e-11 41.4 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EGO54202.1 - 4.8e-06 26.4 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO54202.1 - 4.8e-05 22.4 0.0 0.0014 17.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGO54202.1 - 0.0018 17.2 0.0 0.044 12.7 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EGO54202.1 - 0.037 12.6 0.0 1.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase SE PF08491.5 EGO54202.1 - 0.063 12.0 0.0 0.17 10.6 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Thi4 PF01946.12 EGO54202.1 - 0.071 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Thi4 family tRNA-synt_1e PF01406.14 EGO54203.1 - 8.8e-105 350.1 0.0 3.1e-104 348.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EGO54203.1 - 5.7e-05 21.9 1.2 0.039 12.6 0.0 3.0 4 0 0 4 4 4 2 tRNA synthetases class I (M) DALR_2 PF09190.6 EGO54203.1 - 0.0019 18.4 1.8 0.0021 18.2 0.0 2.0 2 0 0 2 2 2 1 DALR domain tRNA-synt_1c PF00749.16 EGO54203.1 - 0.004 15.8 0.6 0.018 13.7 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain Nuc_deoxyrib_tr PF05014.10 EGO54204.1 - 0.0015 18.4 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase DUF3716 PF12511.3 EGO54205.1 - 7.5e-17 60.6 1.5 1.8e-16 59.4 1.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Cupin_3 PF05899.7 EGO54205.1 - 0.083 12.2 0.0 0.35 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Pkinase PF00069.20 EGO54208.1 - 6.8e-34 117.1 0.0 9.5e-33 113.4 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO54208.1 - 7e-24 84.2 0.0 1.2e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CENP-F_N PF10481.4 EGO54208.1 - 0.0072 15.7 5.0 0.0072 15.7 3.5 1.9 2 0 0 2 2 2 1 Cenp-F N-terminal domain Fmp27_WPPW PF10359.4 EGO54208.1 - 0.016 13.6 1.8 0.029 12.8 1.2 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF342 PF03961.8 EGO54208.1 - 0.023 13.1 3.5 0.036 12.4 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APH PF01636.18 EGO54208.1 - 0.035 13.8 0.6 0.51 10.0 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family Phage_Mu_Gam PF07352.7 EGO54208.1 - 0.11 12.0 4.4 0.12 11.8 2.1 1.7 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein APG6 PF04111.7 EGO54208.1 - 0.41 9.6 7.4 0.89 8.5 5.2 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Kinetocho_Slk19 PF12709.2 EGO54208.1 - 0.79 9.8 9.7 5.7 7.0 6.7 2.3 1 1 0 1 1 1 0 Central kinetochore-associated V_ATPase_I PF01496.14 EGO54208.1 - 2.9 5.6 3.7 3.9 5.2 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EGO54208.1 - 3.6 7.1 9.3 7.1 6.1 6.5 1.4 1 0 0 1 1 1 0 IncA protein bZIP_1 PF00170.16 EGO54209.1 - 0.0001 22.2 4.4 0.00022 21.0 3.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor Complex1_LYR PF05347.10 EGO54211.1 - 1.3e-10 40.8 0.2 1.3e-10 40.8 0.1 2.4 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGO54211.1 - 7e-09 35.7 0.2 7e-09 35.7 0.1 3.1 3 0 0 3 3 3 1 Complex1_LYR-like AT_hook PF02178.14 EGO54211.1 - 0.0005 19.4 25.1 0.12 12.1 2.8 4.0 3 0 0 3 3 3 3 AT hook motif LMBR1 PF04791.11 EGO54211.1 - 7.3 5.0 8.9 11 4.4 6.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein UQ_con PF00179.21 EGO54212.1 - 2.3e-12 46.5 0.1 3e-12 46.1 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGO54212.1 - 0.005 16.7 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain Sec7_N PF12783.2 EGO54213.1 - 4e-30 104.4 4.7 9.3e-29 100.0 0.0 3.8 4 1 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EGO54213.1 - 1e-05 24.9 0.1 0.0015 18.0 0.0 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Band_7 PF01145.20 EGO54214.1 - 7.2e-31 107.4 0.5 7.2e-31 107.4 0.4 2.2 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EGO54214.1 - 0.044 13.2 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Lactamase_B_2 PF12706.2 EGO54218.1 - 2.6e-28 98.8 0.0 5.4e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGO54218.1 - 1.4e-05 24.8 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGO54218.1 - 0.0014 18.3 0.5 0.011 15.3 0.3 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Cupin_2 PF07883.6 EGO54219.1 - 2e-08 33.6 0.1 9e-08 31.5 0.0 2.0 2 0 0 2 2 2 1 Cupin domain Cupin_6 PF12852.2 EGO54219.1 - 0.00019 21.1 0.0 0.00026 20.6 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EGO54219.1 - 0.028 13.7 0.0 0.061 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF1255 PF06865.6 EGO54219.1 - 0.085 13.1 0.2 14 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1255) DUF2179 PF10035.4 EGO54221.1 - 0.09 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) Sugar_tr PF00083.19 EGO54222.1 - 1.9e-119 399.2 19.9 2.2e-119 399.0 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO54222.1 - 4.1e-24 84.9 36.1 8.4e-17 60.9 7.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 EGO54222.1 - 0.38 10.7 5.1 0.16 11.9 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) SGL PF08450.7 EGO54223.1 - 1.7e-07 30.8 0.3 4.4e-06 26.2 0.4 2.2 1 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 EGO54223.1 - 0.11 12.5 0.2 0.72 10.0 0.1 2.5 2 0 0 2 2 2 0 Two component regulator propeller DUF4185 PF13810.1 EGO54224.1 - 4.8e-13 48.6 2.9 6.5e-13 48.2 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Asparaginase_2 PF01112.13 EGO54225.1 - 4e-45 153.9 0.8 4.3e-24 84.8 0.0 3.6 3 1 0 3 3 3 3 Asparaginase Tim17 PF02466.14 EGO54226.1 - 1.9e-34 118.4 5.6 2.3e-34 118.2 3.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 EGO54226.1 - 0.08 12.7 0.0 0.22 11.3 0.0 1.7 1 1 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal DUF2628 PF10947.3 EGO54226.1 - 0.094 12.5 0.2 0.13 12.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) WD40 PF00400.27 EGO54227.1 - 3.7e-24 83.6 2.5 5.8e-05 22.8 0.0 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Peptidase_M20 PF01546.23 EGO54227.1 - 2.8e-23 82.3 0.0 5.3e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGO54227.1 - 2.6e-07 30.3 0.0 4.9e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain zf-RING_2 PF13639.1 EGO54228.1 - 0.002 17.8 7.6 0.019 14.7 5.3 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO54228.1 - 0.01 15.8 1.6 0.01 15.8 1.1 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 EGO54228.1 - 0.12 12.0 4.0 0.13 12.0 0.9 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4 PF00097.20 EGO54228.1 - 0.13 11.8 4.4 1.8 8.2 3.0 2.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGO54228.1 - 0.21 11.3 0.0 0.21 11.3 0.0 3.1 4 0 0 4 4 4 0 RING-type zinc-finger zf-RING_5 PF14634.1 EGO54228.1 - 0.47 10.2 6.5 1.3 8.8 3.7 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGO54228.1 - 1.8 8.2 10.1 0.21 11.2 2.9 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CVNH PF08881.5 EGO54229.1 - 3.4e-06 27.2 0.0 4.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 CVNH domain DUF3437 PF11919.3 EGO54230.1 - 4e-32 109.7 0.1 1.9e-31 107.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HTH_32 PF13565.1 EGO54231.1 - 0.041 14.6 4.7 0.2 12.4 0.1 2.1 1 1 1 2 2 2 0 Homeodomain-like domain Vfa1 PF08432.5 EGO54231.1 - 3.3 7.7 10.3 3.7 7.5 7.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CAP PF00188.21 EGO54232.1 - 1.1e-13 51.7 3.1 1.7e-13 51.1 2.2 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RAP1 PF07218.6 EGO54232.1 - 7.2 4.5 6.1 8.8 4.2 4.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Atg14 PF10186.4 EGO54233.1 - 0.0023 16.9 1.6 0.0023 16.9 1.1 1.8 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Striatin PF08232.7 EGO54233.1 - 0.046 14.0 3.2 0.12 12.7 2.2 1.7 1 0 0 1 1 1 0 Striatin family DUF2205 PF10224.4 EGO54233.1 - 0.13 11.8 2.9 0.27 10.8 2.0 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) IncA PF04156.9 EGO54233.1 - 0.42 10.1 2.8 0.37 10.3 0.8 1.7 2 0 0 2 2 2 0 IncA protein Metal_resist PF13801.1 EGO54233.1 - 6 6.8 12.7 1.4 8.8 4.7 2.6 2 1 0 2 2 2 0 Heavy-metal resistance Methyltransf_31 PF13847.1 EGO54234.1 - 2.3e-30 105.1 0.0 3.8e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO54234.1 - 9.1e-17 61.3 0.0 1.5e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO54234.1 - 2.8e-14 52.8 0.0 1.3e-13 50.6 0.0 2.0 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGO54234.1 - 9.3e-14 51.6 0.0 1.5e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO54234.1 - 4e-10 39.6 0.0 6.5e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO54234.1 - 7.2e-09 36.2 0.0 1.1e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO54234.1 - 3.5e-08 33.4 0.0 6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO54234.1 - 7e-07 29.6 0.0 1.1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGO54234.1 - 0.00051 19.6 0.0 0.00089 18.8 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EGO54234.1 - 0.002 17.2 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EGO54234.1 - 0.0024 17.0 0.0 0.0049 16.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.10 EGO54234.1 - 0.0074 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase DOT1 PF08123.8 EGO54234.1 - 0.021 14.1 0.2 0.039 13.2 0.0 1.6 2 0 0 2 2 2 0 Histone methylation protein DOT1 MTS PF05175.9 EGO54234.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AT_hook PF02178.14 EGO54236.1 - 0.37 10.6 5.7 0.88 9.4 3.9 1.7 1 0 0 1 1 1 0 AT hook motif DUF3716 PF12511.3 EGO54237.1 - 1.7e-16 59.5 4.6 4.2e-16 58.2 3.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) XkdW PF09636.5 EGO54238.1 - 0.016 15.1 1.2 0.016 15.1 0.8 2.4 2 0 0 2 2 2 0 XkdW protein FAT PF02259.18 EGO54240.1 - 1.8e-131 438.3 8.3 4.8e-131 436.9 5.7 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EGO54240.1 - 2.1e-63 213.9 0.5 4.4e-63 212.9 0.4 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EGO54240.1 - 1.1e-59 200.8 1.7 5.4e-58 195.4 0.1 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EGO54240.1 - 8.3e-43 144.5 0.5 8.3e-43 144.5 0.3 3.2 3 0 0 3 3 2 1 Rapamycin binding domain HEAT_2 PF13646.1 EGO54240.1 - 7e-16 58.2 4.0 0.0014 18.8 0.0 7.2 5 2 0 6 6 6 3 HEAT repeats FATC PF02260.15 EGO54240.1 - 1.7e-15 56.1 0.1 4.7e-15 54.7 0.1 1.9 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EGO54240.1 - 1.8e-14 52.4 12.9 0.012 15.6 0.0 10.0 10 0 0 10 10 10 3 HEAT repeat Adaptin_N PF01602.15 EGO54240.1 - 2.2e-09 36.2 6.7 0.00011 20.6 0.0 4.3 4 1 1 5 5 5 3 Adaptin N terminal region HEAT_EZ PF13513.1 EGO54240.1 - 4.5e-08 33.3 16.8 0.0007 19.9 0.0 10.1 10 3 3 13 13 11 2 HEAT-like repeat CLASP_N PF12348.3 EGO54240.1 - 0.00011 21.6 2.7 0.95 8.7 0.0 4.9 4 1 1 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 EGO54240.1 - 0.004 17.4 5.1 41 4.6 0.3 7.0 6 1 1 8 8 8 0 Vacuolar 14 Fab1-binding region PRKCSH-like PF12999.2 EGO54241.1 - 1.4e-40 138.7 6.3 2.2e-23 82.7 0.2 2.9 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EGO54241.1 - 9.1e-31 106.4 3.6 4.5e-30 104.1 0.1 2.8 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EGO54241.1 - 1.2e-11 45.2 0.3 3.5e-11 43.7 0.2 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DFF-C PF09033.5 EGO54241.1 - 0.00078 19.3 0.2 0.00078 19.3 0.1 2.2 2 0 0 2 2 2 1 DNA Fragmentation factor 45kDa, C terminal domain NuA4 PF09340.5 EGO54241.1 - 0.0068 16.0 5.6 0.084 12.5 0.2 2.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 NPV_P10 PF05531.7 EGO54241.1 - 0.012 15.8 2.5 0.057 13.6 0.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 EGO54241.1 - 0.026 13.7 12.7 0.093 11.9 4.8 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4613 PF15390.1 EGO54241.1 - 0.026 12.7 1.7 0.037 12.2 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF684 PF05075.9 EGO54241.1 - 0.045 12.3 0.2 0.094 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF684) Spc24 PF08286.6 EGO54241.1 - 0.052 13.2 0.3 0.052 13.2 0.2 2.9 4 0 0 4 4 2 0 Spc24 subunit of Ndc80 Intein_splicing PF14890.1 EGO54241.1 - 0.081 11.7 0.3 0.16 10.8 0.2 1.4 1 1 0 1 1 1 0 Intein splicing domain FlxA PF14282.1 EGO54241.1 - 0.088 12.7 3.0 0.23 11.4 0.3 2.4 2 0 0 2 2 2 0 FlxA-like protein DUF4047 PF13256.1 EGO54241.1 - 0.09 12.7 8.6 3 7.8 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4047) DUF3450 PF11932.3 EGO54241.1 - 0.12 11.6 10.2 2.9 7.0 3.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) FadA PF09403.5 EGO54241.1 - 0.13 12.3 12.3 0.81 9.7 0.3 2.6 3 0 0 3 3 2 0 Adhesion protein FadA DUF1515 PF07439.6 EGO54241.1 - 0.16 11.7 5.3 0.29 10.9 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) CASP_C PF08172.7 EGO54241.1 - 0.28 10.1 7.3 0.9 8.5 5.1 1.8 1 1 0 1 1 1 0 CASP C terminal ATG16 PF08614.6 EGO54241.1 - 0.38 10.5 15.4 0.5 10.1 2.9 2.8 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) YlqD PF11068.3 EGO54241.1 - 0.43 10.6 7.8 0.46 10.5 2.6 2.4 2 0 0 2 2 2 0 YlqD protein PspB PF06667.7 EGO54241.1 - 0.45 10.4 7.6 0.15 12.0 0.2 2.4 2 0 0 2 2 2 0 Phage shock protein B DUF972 PF06156.8 EGO54241.1 - 0.51 10.7 9.5 1.6 9.1 0.1 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 EGO54241.1 - 0.75 9.9 8.0 0.84 9.7 0.3 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 EGO54241.1 - 0.78 9.5 5.5 4.6 7.0 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 EGO54241.1 - 0.89 7.9 11.8 3 6.1 4.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Spc7 PF08317.6 EGO54241.1 - 1.7 7.2 8.2 4.4 5.8 5.7 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF2721 PF11026.3 EGO54241.1 - 2 8.0 2.9 4.4 6.9 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) BLOC1_2 PF10046.4 EGO54241.1 - 2.2 8.4 7.2 14 5.9 0.4 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3373 PF11853.3 EGO54241.1 - 2.4 6.5 5.6 3.9 5.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) Prefoldin PF02996.12 EGO54241.1 - 3.6 7.2 16.9 0.087 12.4 0.6 3.1 3 1 1 4 4 3 0 Prefoldin subunit Filament PF00038.16 EGO54241.1 - 4.2 6.7 19.1 1.2 8.5 5.1 2.3 3 0 0 3 3 2 0 Intermediate filament protein bZIP_1 PF00170.16 EGO54241.1 - 5 7.1 19.2 1.2 9.1 1.0 3.2 2 1 1 3 3 3 0 bZIP transcription factor V_ATPase_I PF01496.14 EGO54241.1 - 5.2 4.7 7.9 11 3.7 5.5 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Bap31 PF05529.7 EGO54241.1 - 5.9 6.3 5.7 16 4.8 3.9 1.7 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF724 PF05266.9 EGO54241.1 - 8 6.0 8.9 1.4 8.5 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) GCIP PF13324.1 EGO54242.1 - 6.7e-06 25.5 2.7 1e-05 24.9 1.1 1.8 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.8 EGO54242.1 - 0.022 14.3 8.6 0.057 13.0 6.0 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Pox_RNA_Pol_19 PF05320.7 EGO54242.1 - 0.035 13.8 6.0 0.056 13.1 4.2 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF848 PF05852.6 EGO54242.1 - 0.05 13.4 4.4 1.6 8.5 2.5 2.4 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) RRN3 PF05327.6 EGO54242.1 - 0.073 11.1 7.0 0.11 10.6 4.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF506 PF04720.7 EGO54242.1 - 0.1 12.2 3.1 0.21 11.2 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF506) CobT PF06213.7 EGO54242.1 - 0.24 10.4 12.7 0.36 9.9 8.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Dicty_REP PF05086.7 EGO54242.1 - 0.26 9.0 7.0 0.36 8.5 4.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDC45 PF02724.9 EGO54242.1 - 0.27 9.2 6.1 0.36 8.8 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein YlbD_coat PF14071.1 EGO54242.1 - 0.35 10.9 4.0 2.7 8.0 2.2 2.2 2 0 0 2 2 2 0 Putative coat protein CotH PF08757.6 EGO54242.1 - 0.36 10.0 5.2 0.57 9.3 3.6 1.3 1 0 0 1 1 1 0 CotH protein BSP_II PF05432.6 EGO54242.1 - 0.49 9.6 12.6 0.055 12.7 5.8 1.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 EGO54242.1 - 0.53 9.9 6.5 1.1 8.9 4.5 1.4 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.5 EGO54242.1 - 0.82 9.9 16.0 0.88 9.8 10.2 1.7 2 0 0 2 2 1 0 Centromere protein B dimerisation domain Upf2 PF04050.9 EGO54242.1 - 0.92 9.2 13.6 1.4 8.6 9.4 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Vfa1 PF08432.5 EGO54242.1 - 1.2 9.1 8.4 1.8 8.5 5.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BTV_NS2 PF04514.7 EGO54242.1 - 1.3 7.8 7.1 2 7.2 4.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 NOA36 PF06524.7 EGO54242.1 - 1.9 7.6 9.7 2.5 7.2 6.7 1.1 1 0 0 1 1 1 0 NOA36 protein PolC_DP2 PF03833.8 EGO54242.1 - 2 5.9 5.8 2.8 5.4 4.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Nop14 PF04147.7 EGO54242.1 - 2.4 5.9 14.6 3.9 5.2 10.1 1.3 1 0 0 1 1 1 0 Nop14-like family DUF4564 PF15169.1 EGO54242.1 - 3 7.5 5.0 4.8 6.8 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) Nucleoplasmin PF03066.10 EGO54242.1 - 3.4 7.1 18.2 5.7 6.4 12.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 EGO54242.1 - 5.9 7.1 13.8 9.4 6.4 8.8 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4611) TRAP_alpha PF03896.11 EGO54242.1 - 6.1 5.7 10.4 8.7 5.2 7.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PBP1_TM PF14812.1 EGO54242.1 - 6.7 7.0 11.4 13 6.1 7.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Daxx PF03344.10 EGO54242.1 - 8.1 4.7 15.3 13 4.1 10.6 1.2 1 0 0 1 1 1 0 Daxx Family Cu-oxidase_2 PF07731.9 EGO54243.1 - 2.1e-39 134.1 7.2 5.2e-39 132.9 0.6 3.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGO54243.1 - 8.5e-32 109.3 4.7 4.6e-31 106.9 0.8 3.2 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 EGO54243.1 - 1.3e-26 93.4 0.1 3.3e-26 92.0 0.0 1.7 2 0 0 2 2 2 1 Multicopper oxidase IncA PF04156.9 EGO54245.1 - 3.1e-07 30.1 1.7 7e-07 29.0 1.2 1.5 1 0 0 1 1 1 1 IncA protein APG6 PF04111.7 EGO54245.1 - 9.7 5.1 12.4 16 4.4 8.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 RRM_5 PF13893.1 EGO54246.1 - 0.0097 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 EGO54246.1 - 0.025 14.2 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain Cyto_heme_lyase PF01265.12 EGO54247.1 - 3e-79 266.2 0.0 7.5e-79 264.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase ABC1 PF03109.11 EGO54248.1 - 1.3e-27 96.1 0.0 1.4e-17 63.7 0.0 2.6 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 EGO54248.1 - 0.011 15.5 0.1 0.026 14.2 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Lumazine_bd PF12870.2 EGO54248.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Lumazine-binding domain Glyco_hydro_71 PF03659.9 EGO54249.1 - 1e-102 343.5 3.4 1.1e-102 343.3 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Ribosomal_S28e PF01200.13 EGO54250.1 - 1.8e-33 114.0 2.9 2e-33 113.9 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e RhgB_N PF09284.5 EGO54251.1 - 5.3e-123 409.2 5.7 5.3e-123 409.2 4.0 1.5 2 0 0 2 2 2 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EGO54251.1 - 8.3e-59 197.9 0.0 1.8e-58 196.8 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EGO54251.1 - 1.9e-18 66.3 1.1 4.5e-18 65.1 0.8 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EGO54251.1 - 5.9e-06 26.2 4.9 1.8e-05 24.6 1.6 3.2 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain DUF3823 PF12866.2 EGO54251.1 - 0.0041 16.6 0.0 0.0084 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3823) DUF2012 PF09430.5 EGO54251.1 - 0.024 14.4 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Sugar_tr PF00083.19 EGO54252.1 - 2.6e-90 303.1 17.6 3e-90 302.9 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO54252.1 - 1.9e-24 86.0 51.0 2e-20 72.8 20.3 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF373 PF04123.8 EGO54253.1 - 0.081 11.9 0.5 0.14 11.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Aldo_ket_red PF00248.16 EGO54255.1 - 1.4e-55 188.1 0.0 1.7e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Bac_surface_Ag PF01103.18 EGO54256.1 - 5.9e-38 131.1 0.2 8.9e-38 130.5 0.0 1.4 2 0 0 2 2 2 1 Surface antigen BetaGal_dom3 PF13363.1 EGO54256.1 - 0.082 12.3 0.0 0.23 10.8 0.0 1.7 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 UQ_con PF00179.21 EGO54257.1 - 1.2e-25 89.6 0.2 1.6e-25 89.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ABC2_membrane PF01061.19 EGO54258.1 - 1.8e-95 318.0 58.6 1.2e-49 168.2 15.2 3.2 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EGO54258.1 - 3.7e-39 132.5 7.3 6e-35 119.0 0.1 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 EGO54258.1 - 1.2e-35 122.7 0.0 1e-16 61.5 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 EGO54258.1 - 3.7e-23 81.4 0.1 9.7e-23 80.0 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 EGO54258.1 - 1.3e-07 31.7 0.1 1.4e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EGO54258.1 - 6.3e-07 28.9 0.0 0.001 18.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EGO54258.1 - 1.7e-05 24.7 0.0 0.22 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 EGO54258.1 - 3e-05 23.5 0.2 0.0077 15.6 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EGO54258.1 - 6.1e-05 22.2 0.0 0.0018 17.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGO54258.1 - 8.6e-05 22.6 0.0 0.28 11.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EGO54258.1 - 0.00051 20.0 0.0 1.1 9.1 0.0 3.1 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EGO54258.1 - 0.00063 19.2 0.4 0.026 14.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGO54258.1 - 0.0014 19.4 0.0 0.21 12.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EGO54258.1 - 0.0018 17.9 0.2 0.87 9.2 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EGO54258.1 - 0.002 17.8 1.8 0.82 9.4 0.2 2.6 2 0 0 2 2 2 2 Part of AAA domain UPF0079 PF02367.12 EGO54258.1 - 0.0045 16.6 0.4 2 8.0 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 EGO54258.1 - 0.01 15.0 0.0 1.7 7.7 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EGO54258.1 - 0.011 16.0 0.1 0.75 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EGO54258.1 - 0.015 15.5 0.0 3.6 7.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGO54258.1 - 0.025 14.5 0.1 0.89 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EGO54258.1 - 0.11 12.1 0.0 5.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Viral_helicase1 PF01443.13 EGO54258.1 - 0.11 11.9 0.1 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 EGO54258.1 - 0.11 12.7 0.1 0.52 10.5 0.0 2.2 2 0 0 2 2 1 0 AAA domain Miro PF08477.8 EGO54258.1 - 0.12 12.8 0.0 28 5.2 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 EGO54258.1 - 0.16 11.5 0.2 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EGO54258.1 - 0.16 10.8 0.0 3.2 6.5 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.1 EGO54258.1 - 0.19 11.6 0.0 22 4.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EGO54258.1 - 0.19 11.1 0.0 21 4.4 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein CAF-1_p150 PF11600.3 EGO54260.1 - 0.0046 16.3 10.6 0.0046 16.3 7.3 3.0 3 0 0 3 3 3 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ferric_reduct PF01794.14 EGO54260.1 - 0.3 11.1 0.0 0.48 10.5 0.0 1.2 1 0 0 1 1 1 0 Ferric reductase like transmembrane component PAP_assoc PF03828.14 EGO54262.1 - 5.7e-14 51.8 0.3 1e-13 50.9 0.2 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase Actin PF00022.14 EGO54263.1 - 8.3e-113 376.7 0.0 9.6e-113 376.5 0.0 1.0 1 0 0 1 1 1 1 Actin Ldh_2 PF02615.9 EGO54264.1 - 1.9e-93 312.8 0.0 2.2e-93 312.6 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Sugar_tr PF00083.19 EGO54265.1 - 7.4e-69 232.4 20.2 9.5e-69 232.1 14.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO54265.1 - 1.6e-13 50.1 30.9 4.5e-12 45.3 17.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Peptidase_A4 PF01828.12 EGO54267.1 - 3.3e-37 127.5 11.0 4.3e-37 127.1 7.6 1.1 1 0 0 1 1 1 1 Peptidase A4 family F-box PF00646.28 EGO54269.1 - 0.024 14.2 1.3 1.4 8.6 0.0 3.5 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 EGO54269.1 - 0.032 13.9 1.8 0.038 13.7 0.1 2.1 2 0 0 2 2 2 0 F-box-like Baculo_LEF5_C PF11792.3 EGO54269.1 - 4 6.8 8.0 0.23 10.8 0.1 2.8 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain MFS_1 PF07690.11 EGO54270.1 - 6.5e-46 156.6 37.5 6.5e-46 156.6 26.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO54270.1 - 4.4e-14 51.9 12.4 4.4e-14 51.9 8.6 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter Glyco_hydro_3 PF00933.16 EGO54273.1 - 8.2e-82 274.5 0.0 1.1e-81 274.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO54273.1 - 3.8e-46 157.4 0.0 2.2e-45 154.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGO54273.1 - 3.1e-24 84.6 0.1 6.2e-24 83.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Acetyltransf_1 PF00583.19 EGO54276.1 - 1.1e-06 28.5 0.2 7.6e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGO54276.1 - 0.00011 22.3 0.0 0.0014 18.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO54276.1 - 0.00094 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EGO54276.1 - 0.0022 18.1 0.3 0.0076 16.4 0.2 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO54276.1 - 0.0086 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGO54276.1 - 0.15 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LmjF365940-deam PF14421.1 EGO54278.1 - 0.13 11.6 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Apt1 PF10351.4 EGO54279.1 - 0.13 11.0 2.9 1.5 7.6 2.7 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain Microtub_assoc PF07989.6 EGO54280.1 - 0.24 11.2 2.3 0.57 10.0 0.1 2.1 2 0 0 2 2 2 0 Microtubule associated SpaB_C PF14028.1 EGO54284.1 - 0.29 10.6 1.8 0.4 10.1 1.3 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain PWWP PF00855.12 EGO54287.1 - 0.094 12.9 3.4 0.12 12.5 0.1 2.6 2 0 0 2 2 2 0 PWWP domain OmpH PF03938.9 EGO54287.1 - 3.6 7.5 7.3 2.5 8.0 3.4 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Pex24p PF06398.6 EGO54289.1 - 1.8e-108 362.5 0.0 2.4e-108 362.1 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Metallothio_2 PF01439.13 EGO54291.1 - 1.5 9.4 10.4 0.15 12.6 3.2 1.9 2 0 0 2 2 2 0 Metallothionein DUF3818 PF12825.2 EGO54292.1 - 2.6e-37 128.3 0.0 5.2e-23 81.2 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EGO54292.1 - 2.9e-34 117.6 0.0 9e-34 116.0 0.0 1.8 2 0 0 2 2 2 1 PX-associated Tax PF02959.11 EGO54292.1 - 0.0042 16.5 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 HTLV Tax Thiolase_N PF00108.18 EGO54295.1 - 1.4e-74 250.4 0.3 1.9e-74 249.9 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGO54295.1 - 3.7e-42 142.6 1.5 5.5e-41 138.8 0.3 2.5 3 0 0 3 3 3 1 Thiolase, C-terminal domain Dynamin_N PF00350.18 EGO54296.1 - 2.7e-13 50.1 0.0 1.6e-12 47.6 0.0 2.3 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EGO54296.1 - 0.00058 19.8 0.1 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran PF00005.22 EGO54296.1 - 0.0085 16.3 0.1 0.039 14.2 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Vint PF14623.1 EGO54299.1 - 1.5e-33 115.6 0.0 2.3e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 EGO54299.1 - 9.9e-33 112.1 0.0 2.3e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 EGO54299.1 - 5.3e-21 75.4 0.0 1e-20 74.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EGO54299.1 - 6.1e-15 55.3 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EGO54299.1 - 5.7e-13 48.8 0.1 4.6e-11 42.6 0.0 2.5 1 1 1 2 2 2 1 von Willebrand factor type A domain Ribosomal_L13e PF01294.13 EGO54300.1 - 2.1e-61 206.5 3.1 2.8e-61 206.1 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Arm PF00514.18 EGO54301.1 - 0.0019 17.9 3.7 7.6 6.5 0.1 4.5 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Ribosomal_L50 PF10501.4 EGO54302.1 - 1.1e-25 89.7 0.6 2e-25 88.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal subunit 39S DUF1771 PF08590.5 EGO54302.1 - 0.047 13.7 0.4 0.15 12.0 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) COX14 PF14880.1 EGO54303.1 - 8.2e-21 73.3 0.1 8.2e-21 73.3 0.1 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF2413 PF10310.4 EGO54303.1 - 0.47 9.2 11.4 0.65 8.7 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DAHP_synth_1 PF00793.15 EGO54305.1 - 2.1e-102 341.4 0.1 2.6e-102 341.1 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Mito_fiss_reg PF05308.6 EGO54306.1 - 0.37 10.1 10.5 0.48 9.7 7.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF2360 PF10152.4 EGO54306.1 - 0.4 10.9 2.0 0.52 10.5 1.4 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 EGO54306.1 - 6.1 6.1 9.9 7 5.9 6.8 1.1 1 0 0 1 1 1 0 Vta1 like MFS_1 PF07690.11 EGO54307.1 - 1.7e-27 96.0 51.3 2.9e-25 88.7 35.4 3.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO54307.1 - 1.6e-05 23.7 14.9 1.6e-05 23.7 10.3 3.6 4 1 0 4 4 4 1 Sugar (and other) transporter LRR_4 PF12799.2 EGO54308.1 - 2.5e-39 132.2 48.4 2e-08 33.6 2.0 10.7 4 3 7 12 12 12 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO54308.1 - 1.6e-34 117.4 46.2 5.6e-09 35.6 3.4 9.3 5 3 7 12 12 12 10 Leucine rich repeat LRR_1 PF00560.28 EGO54308.1 - 4.2e-22 74.7 47.2 0.0024 17.6 1.9 16.4 17 0 0 17 17 17 7 Leucine Rich Repeat LRR_7 PF13504.1 EGO54308.1 - 2.3e-11 41.9 43.4 0.99 9.8 0.0 13.8 15 0 0 15 15 15 4 Leucine rich repeat LRR_6 PF13516.1 EGO54308.1 - 3.7e-08 32.6 41.5 3.1 8.1 0.0 13.3 15 0 0 15 15 15 4 Leucine Rich repeat DUF2322 PF10084.4 EGO54308.1 - 0.099 12.3 0.0 11 5.7 0.0 3.5 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2322) LRR_9 PF14580.1 EGO54308.1 - 0.17 11.4 10.1 2.4 7.7 0.1 4.0 2 1 3 5 5 5 0 Leucine-rich repeat DPM3 PF08285.6 EGO54309.1 - 5.8e-33 112.6 0.5 6.4e-33 112.4 0.3 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3007 PF11460.3 EGO54309.1 - 0.045 13.8 0.1 0.052 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Pribosyltran PF00156.22 EGO54311.1 - 5.5e-10 39.0 0.2 3.6e-09 36.4 0.1 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Oxidored-like PF09791.4 EGO54312.1 - 8.7e-26 89.1 2.4 2e-25 87.9 1.6 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal PAT1 PF09770.4 EGO54312.1 - 1.6 6.8 11.6 2.8 6.0 8.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CPDase PF07823.6 EGO54314.1 - 1.7e-45 154.9 0.0 1.9e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 EGO54314.1 - 0.0096 15.6 0.0 0.5 10.0 0.0 2.3 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily DUF605 PF04652.11 EGO54316.1 - 4.9 6.4 8.5 5.8 6.1 5.9 1.1 1 0 0 1 1 1 0 Vta1 like FAA_hydrolase PF01557.13 EGO54317.1 - 1.8e-53 181.2 0.0 2.4e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EGO54317.1 - 2.9e-28 97.9 0.0 5.1e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Fungal_trans PF04082.13 EGO54318.1 - 2.2e-13 49.7 0.3 6.3e-13 48.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO54318.1 - 1.9e-08 34.0 9.1 3.3e-08 33.2 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1194 PF06707.6 EGO54318.1 - 0.023 13.6 0.0 0.054 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) adh_short PF00106.20 EGO54319.1 - 5.2e-06 26.4 0.0 9.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Sulfatase PF00884.18 EGO54320.1 - 0.012 14.8 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Sulfatase Trypan_PARP PF05887.6 EGO54321.1 - 0.00072 19.3 4.2 0.00072 19.3 2.9 2.6 2 1 1 3 3 3 1 Procyclic acidic repetitive protein (PARP) Chromo PF00385.19 EGO54322.1 - 8.4e-11 41.3 2.1 3.5e-10 39.4 1.4 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 EGO54322.1 - 0.0004 20.2 0.1 0.0019 18.0 0.0 2.1 2 0 0 2 2 2 1 Polycomb-like MTF2 factor 2 Ndc1_Nup PF09531.5 EGO54322.1 - 5.2 5.3 7.0 6 5.1 4.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Plasmodium_Vir PF05795.6 EGO54322.1 - 8.4 5.4 15.2 16 4.5 10.5 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3083 PF11281.3 EGO54323.1 - 0.066 12.3 0.0 0.066 12.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) B12-binding_2 PF02607.12 EGO54323.1 - 0.11 12.5 0.1 0.12 12.4 0.0 1.2 1 1 0 1 1 1 0 B12 binding domain TMF_TATA_bd PF12325.3 EGO54325.1 - 0.34 10.6 3.2 0.2 11.3 0.2 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding HMGL-like PF00682.14 EGO54326.1 - 5.9e-71 238.8 0.2 8.7e-71 238.3 0.1 1.3 1 0 0 1 1 1 1 HMGL-like Trp_syntA PF00290.15 EGO54326.1 - 0.076 11.5 0.0 10 4.5 0.0 2.3 2 0 0 2 2 2 0 Tryptophan synthase alpha chain NRDE PF05742.7 EGO54327.1 - 1.2e-36 126.4 0.0 2.1e-34 119.0 0.0 2.8 1 1 0 1 1 1 1 NRDE protein Tfb2 PF03849.9 EGO54329.1 - 1.1e-121 405.9 0.0 4e-114 381.0 0.0 2.1 1 1 1 2 2 2 2 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EGO54329.1 - 3.5e-05 23.5 0.1 0.00014 21.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain 4HBT PF03061.17 EGO54330.1 - 1.3e-12 47.6 0.1 2e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EGO54330.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) TB2_DP1_HVA22 PF03134.14 EGO54331.1 - 1.7e-30 104.5 9.1 2.6e-30 104.0 6.3 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Nsp1_C PF05064.8 EGO54331.1 - 0.0038 16.8 0.3 0.0086 15.7 0.0 1.6 2 0 0 2 2 2 1 Nsp1-like C-terminal region CASP_C PF08172.7 EGO54331.1 - 0.11 11.5 0.0 0.22 10.4 0.0 1.5 1 0 0 1 1 1 0 CASP C terminal MFS_1 PF07690.11 EGO54333.1 - 4.5e-38 130.8 17.5 3.5e-37 127.9 13.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 EGO54333.1 - 0.07 12.6 0.4 12 5.4 0.3 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Cu_amine_oxid PF01179.15 EGO54334.1 - 4.6e-171 569.1 0.0 5.5e-171 568.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EGO54334.1 - 2e-21 75.9 0.0 3.7e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EGO54334.1 - 1.2e-13 50.9 0.0 2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CHCH PF06747.8 EGO54335.1 - 0.0001 22.1 6.0 0.00016 21.4 4.2 1.3 1 0 0 1 1 1 1 CHCH domain BPL_N PF09825.4 EGO54336.1 - 1.2e-139 465.2 0.0 1.6e-139 464.8 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EGO54336.1 - 4.2e-21 75.2 0.0 7.8e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EGO54336.1 - 0.0023 17.5 0.4 0.0042 16.7 0.3 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Pam16 PF03656.8 EGO54338.1 - 1.7e-37 128.0 2.1 2e-37 127.8 1.5 1.0 1 0 0 1 1 1 1 Pam16 Yip1 PF04893.12 EGO54339.1 - 4.4e-07 29.5 15.0 6e-06 25.8 4.8 2.5 2 1 0 2 2 2 2 Yip1 domain RCC1 PF00415.13 EGO54340.1 - 4.1e-59 196.5 1.9 2e-08 34.3 0.0 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGO54340.1 - 9.5e-38 127.0 19.7 1.7e-07 30.6 0.1 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 EGO54340.1 - 0.0003 20.2 0.2 0.21 11.1 0.1 2.7 2 0 0 2 2 2 2 Putative carbohydrate binding domain TFIIA PF03153.8 EGO54340.1 - 0.005 16.8 13.7 0.0072 16.2 9.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit U79_P34 PF03064.11 EGO54341.1 - 1.6 8.1 7.5 2.1 7.7 5.2 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Methyltransf_16 PF10294.4 EGO54344.1 - 4e-28 98.0 0.0 6.3e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EGO54344.1 - 0.026 13.9 0.0 0.055 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 EGO54344.1 - 0.045 14.3 0.1 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 EGO54344.1 - 0.14 11.2 0.2 0.3 10.1 0.1 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) dCMP_cyt_deam_1 PF00383.17 EGO54345.1 - 3.2e-06 26.7 0.0 5.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Apyrase PF06079.6 EGO54345.1 - 0.047 12.8 0.0 0.056 12.5 0.0 1.1 1 0 0 1 1 1 0 Apyrase Bd3614-deam PF14439.1 EGO54345.1 - 0.07 12.9 0.0 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase DUF3292 PF11696.3 EGO54346.1 - 0.00043 18.2 0.0 0.00062 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) UBN2 PF14223.1 EGO54346.1 - 0.06 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF3618 PF12277.3 EGO54346.1 - 0.19 11.8 3.7 0.8 9.7 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) DUF3131 PF11329.3 EGO54347.1 - 0.043 12.5 0.0 0.054 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) DUF4175 PF13779.1 EGO54348.1 - 0.0022 15.8 28.0 0.0029 15.4 19.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) FimP PF09766.4 EGO54348.1 - 0.027 13.5 19.7 0.047 12.7 13.7 1.3 1 0 0 1 1 1 0 Fms-interacting protein AAA_23 PF13476.1 EGO54348.1 - 0.037 14.3 12.8 0.059 13.6 8.9 1.3 1 0 0 1 1 1 0 AAA domain SKIP_SNW PF02731.10 EGO54348.1 - 0.15 11.4 21.2 0.13 11.7 1.1 2.5 2 0 0 2 2 2 0 SKIP/SNW domain WASH-7_C PF14746.1 EGO54348.1 - 0.28 10.7 7.5 0.49 9.9 5.2 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Serinc PF03348.10 EGO54348.1 - 0.36 9.4 8.6 0.58 8.8 5.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4557 PF15101.1 EGO54348.1 - 0.37 10.5 26.8 0.71 9.6 18.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Band_3_cyto PF07565.8 EGO54348.1 - 0.62 9.5 9.7 1.1 8.7 6.7 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain G0-G1_switch_2 PF15103.1 EGO54348.1 - 0.82 9.9 9.3 2.3 8.4 6.5 1.8 1 0 0 1 1 1 0 G0/G1 switch protein 2 RR_TM4-6 PF06459.7 EGO54348.1 - 0.88 9.4 10.7 0.57 10.0 6.0 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.4 EGO54348.1 - 1.2 7.3 32.1 0.063 11.5 18.3 1.6 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 EGO54348.1 - 1.7 6.1 11.9 2.6 5.5 8.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.9 EGO54348.1 - 2.3 7.8 21.1 0.014 15.1 7.2 2.2 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) Peptidase_S49_N PF08496.5 EGO54348.1 - 2.6 7.7 10.3 4.7 6.9 7.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ACCA PF03255.9 EGO54348.1 - 3 7.3 13.8 0.63 9.5 7.0 1.7 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit AIF_C PF14721.1 EGO54348.1 - 4 7.7 11.4 9.9 6.4 7.9 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Tmp39 PF10271.4 EGO54348.1 - 6.8 5.2 6.5 10 4.6 4.5 1.1 1 0 0 1 1 1 0 Putative transmembrane protein Kei1 PF08552.6 EGO54348.1 - 9.2 5.8 7.4 19 4.8 5.1 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4593 PF15263.1 EGO54350.1 - 0.0047 16.8 0.2 0.0068 16.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4593) Omega-toxin PF06357.6 EGO54350.1 - 0.25 10.9 1.8 7.7 6.1 0.1 2.4 2 0 0 2 2 2 0 Omega-atracotoxin DUF1010 PF06231.6 EGO54352.1 - 0.024 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) YihI PF04220.7 EGO54353.1 - 0.0092 15.3 2.3 0.012 14.9 1.6 1.1 1 0 0 1 1 1 1 Der GTPase activator (YihI) Spt20 PF12090.3 EGO54353.1 - 0.016 14.5 0.2 0.019 14.3 0.2 1.1 1 0 0 1 1 1 0 Spt20 family DUF3439 PF11921.3 EGO54353.1 - 0.018 14.7 0.6 0.029 14.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Zip PF02535.17 EGO54353.1 - 0.026 13.5 2.9 0.03 13.3 2.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 EGO54353.1 - 0.44 8.7 5.8 0.56 8.4 4.0 1.0 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 EGO54353.1 - 1.8 8.3 11.1 2.2 8.0 7.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.9 EGO54353.1 - 5.8 6.2 13.2 8.9 5.6 9.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CorA PF01544.13 EGO54356.1 - 2.2e-12 46.6 0.9 9.1e-11 41.3 0.0 2.7 3 0 0 3 3 3 2 CorA-like Mg2+ transporter protein 7TM-7TMR_HD PF07698.6 EGO54356.1 - 0.13 11.6 0.1 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase RESP18 PF14948.1 EGO54358.1 - 7.3 6.6 6.6 6.2 6.9 1.8 2.3 1 1 1 2 2 2 0 RESP18 domain Methyltransf_23 PF13489.1 EGO54359.1 - 3.2e-21 75.7 0.0 6.1e-21 74.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO54359.1 - 1.5e-15 57.0 0.0 1.8e-13 50.3 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO54359.1 - 1.7e-12 47.6 0.0 1.3e-11 44.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO54359.1 - 1.4e-11 44.6 0.0 3.8e-11 43.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO54359.1 - 3.8e-10 40.3 0.0 4.4e-09 36.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO54359.1 - 7.2e-06 26.2 0.0 1.8e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO54359.1 - 0.0001 21.5 0.0 0.0012 17.9 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGO54359.1 - 0.00062 19.7 0.0 0.005 16.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 EGO54359.1 - 0.00079 18.6 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 EGO54359.1 - 0.0014 18.0 0.0 0.0058 16.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 EGO54359.1 - 0.0031 17.5 0.0 0.0081 16.1 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EGO54359.1 - 0.01 14.9 0.0 0.1 11.6 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.4 EGO54359.1 - 0.029 13.8 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 EGO54359.1 - 0.059 12.4 0.0 0.11 11.5 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.7 EGO54359.1 - 0.078 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PrmA PF06325.8 EGO54359.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DAO PF01266.19 EGO54360.1 - 1.7e-54 185.1 0.2 1.9e-54 184.9 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO54360.1 - 0.00016 21.7 0.3 0.11 12.5 0.0 2.5 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO54360.1 - 0.0013 18.6 0.2 0.0035 17.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGO54360.1 - 0.065 12.9 0.1 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding HgmA PF04209.8 EGO54361.1 - 9.5e-174 577.7 0.0 1.1e-173 577.5 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase CVNH PF08881.5 EGO54365.1 - 1.6e-32 111.7 0.2 1.8e-32 111.6 0.1 1.0 1 0 0 1 1 1 1 CVNH domain PQQ_3 PF13570.1 EGO54367.1 - 0.0084 16.3 0.1 0.049 13.9 0.0 2.5 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 EGO54367.1 - 0.013 15.0 0.0 0.043 13.3 0.0 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat Period_C PF12114.3 EGO54367.1 - 9.2 5.8 10.7 18 4.8 7.4 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region MFS_1 PF07690.11 EGO54368.1 - 4.6e-35 120.9 53.0 4.6e-35 120.9 36.7 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Striatin PF08232.7 EGO54369.1 - 0.0018 18.6 0.2 0.064 13.5 0.0 2.3 2 0 0 2 2 2 1 Striatin family DUF2046 PF09755.4 EGO54369.1 - 0.54 9.1 0.0 0.54 9.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) RRM_1 PF00076.17 EGO54372.1 - 1.4e-10 40.6 0.1 2.6e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO54372.1 - 2.6e-08 33.7 0.0 4.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGO54372.1 - 0.00012 21.8 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EGO54372.1 - 0.032 14.0 0.1 0.097 12.5 0.0 1.8 1 0 0 1 1 1 0 RNA binding motif RRM_5 PF13893.1 EGO54372.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cupin_8 PF13621.1 EGO54373.1 - 1.3e-22 80.5 0.0 2.7e-22 79.4 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EGO54373.1 - 0.0055 16.9 0.0 0.1 12.8 0.0 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 EGO54373.1 - 0.0072 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.6 EGO54373.1 - 0.037 13.5 0.0 0.097 12.1 0.0 1.6 1 0 0 1 1 1 0 Cupin domain CK_II_beta PF01214.13 EGO54374.1 - 1.6e-77 259.1 0.0 2.9e-77 258.3 0.0 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 EGO54374.1 - 0.0046 17.5 3.9 0.0046 17.5 2.7 2.3 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Orbi_VP6 PF01516.11 EGO54374.1 - 0.11 11.5 1.6 0.17 10.9 1.1 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 Nop25 PF09805.4 EGO54374.1 - 0.14 12.2 2.5 0.1 12.6 0.4 1.7 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) ABC2_membrane PF01061.19 EGO54375.1 - 6.1e-81 270.5 61.9 1.9e-43 148.0 14.4 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EGO54375.1 - 1.4e-34 119.3 0.0 3.1e-17 63.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EGO54375.1 - 1.8e-29 101.3 2.7 3.6e-26 90.8 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EGO54375.1 - 8.3e-10 38.6 0.3 3.8e-09 36.4 0.0 2.4 3 0 0 3 3 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 EGO54375.1 - 4.6e-07 29.7 0.0 0.013 15.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EGO54375.1 - 7.7e-07 28.4 33.8 8e-05 21.8 8.0 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EGO54375.1 - 5.9e-06 26.4 0.1 0.037 14.0 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_22 PF13401.1 EGO54375.1 - 2.6e-05 24.3 0.0 0.26 11.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EGO54375.1 - 3.6e-05 23.2 4.4 0.0043 16.4 0.1 3.2 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EGO54375.1 - 6.8e-05 22.3 0.2 0.0048 16.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EGO54375.1 - 8.1e-05 22.1 2.4 0.02 14.3 0.4 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EGO54375.1 - 0.00013 21.5 0.9 0.5 10.0 0.1 2.6 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 EGO54375.1 - 0.00072 20.3 0.0 0.036 14.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGO54375.1 - 0.0009 19.2 3.3 0.098 12.6 0.1 3.4 3 1 0 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 EGO54375.1 - 0.00099 18.3 0.0 0.0063 15.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EGO54375.1 - 0.0014 18.9 0.1 0.36 11.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EGO54375.1 - 0.0023 17.6 0.4 1.5 8.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.14 EGO54375.1 - 0.0042 16.3 0.0 0.57 9.3 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 EGO54375.1 - 0.0046 16.6 2.2 2.2 8.0 0.1 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_28 PF13521.1 EGO54375.1 - 0.0061 16.5 0.2 0.033 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EGO54375.1 - 0.0088 16.5 0.0 5.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 EGO54375.1 - 0.02 14.3 0.0 3.2 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EGO54375.1 - 0.024 14.1 0.2 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EGO54375.1 - 0.068 12.8 0.0 6.3 6.4 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 EGO54375.1 - 0.11 12.0 0.2 5.2 6.6 0.2 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EGO54375.1 - 0.12 12.6 0.2 50 4.1 0.0 3.6 3 0 0 3 3 3 0 RNA helicase AAA_15 PF13175.1 EGO54375.1 - 0.32 10.0 0.0 2 7.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EGO54375.1 - 0.43 10.8 0.0 0.43 10.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain DUF1295 PF06966.7 EGO54376.1 - 6.4e-40 136.9 2.0 4.7e-38 130.8 1.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 EGO54376.1 - 0.00021 21.0 0.1 0.00043 20.0 0.0 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase p450 PF00067.17 EGO54377.1 - 2.4e-54 184.5 0.0 3.3e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ScdA_N PF04405.9 EGO54378.1 - 0.09 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) PEPCK_ATP PF01293.15 EGO54379.1 - 1.1e-217 723.1 0.0 1.3e-217 722.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 EGO54379.1 - 0.022 15.0 0.1 4.9 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGO54379.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EGO54379.1 - 0.086 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EGO54379.1 - 0.17 11.4 0.5 0.41 10.2 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain EF-hand_1 PF00036.27 EGO54382.1 - 1.3e-20 71.0 7.0 4.6e-07 28.6 0.1 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EGO54382.1 - 3.3e-19 68.7 1.1 2.5e-11 43.5 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EGO54382.1 - 3.9e-19 67.9 5.6 1.9e-10 40.2 0.2 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EGO54382.1 - 9.4e-18 62.4 6.1 1.4e-06 27.7 0.2 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 EGO54382.1 - 1.4e-11 43.1 8.9 6.2e-05 22.1 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EGO54382.1 - 2.4e-05 24.1 0.0 0.00053 19.8 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.8 EGO54382.1 - 0.0065 16.0 0.0 0.22 11.0 0.0 2.0 2 0 0 2 2 2 1 Caleosin related protein EF-hand_4 PF12763.2 EGO54382.1 - 0.0075 15.9 0.2 0.73 9.6 0.0 2.4 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 EGO54382.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Ca2+ insensitive EF hand EF-hand_like PF09279.6 EGO54382.1 - 0.1 12.6 0.1 0.66 10.0 0.0 2.1 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like BUD22 PF09073.5 EGO54383.1 - 2.6e-70 237.6 63.8 2.4e-47 162.0 22.2 2.2 1 1 1 2 2 2 2 BUD22 Sec3_C PF09763.4 EGO54384.1 - 9e-265 880.1 0.0 1.3e-264 879.7 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EGO54384.1 - 3.9e-30 103.5 0.0 7.1e-30 102.7 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 EGO54384.1 - 0.0046 17.0 0.6 0.027 14.6 0.0 2.5 2 0 0 2 2 2 1 Sec3 exocyst complex subunit Peptidase_S9_N PF02897.10 EGO54385.1 - 0.034 12.7 0.1 0.035 12.6 0.1 1.0 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Lycopene_cycl PF05834.7 EGO54385.1 - 0.096 11.5 1.3 0.1 11.4 0.9 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein MSP1_C PF07462.6 EGO54385.1 - 4.1 5.6 8.2 4.6 5.5 5.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus HECT PF00632.20 EGO54387.1 - 1.6e-80 270.6 0.0 2.7e-80 269.9 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 EGO54387.1 - 1.2e-07 31.2 5.0 0.032 14.0 0.0 5.5 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EGO54387.1 - 0.00045 20.0 1.6 0.96 9.6 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat RRN3 PF05327.6 EGO54387.1 - 0.18 9.8 15.9 0.042 11.9 4.2 2.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Methyltransf_11 PF08241.7 EGO54388.1 - 3e-17 62.8 0.0 4.3e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO54388.1 - 4.6e-15 56.1 0.0 7.8e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO54388.1 - 4.6e-14 52.2 0.0 5.8e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO54388.1 - 1.4e-12 47.6 0.0 2.3e-12 46.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO54388.1 - 8.2e-12 45.4 0.0 1.1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO54388.1 - 4e-09 36.7 0.0 5.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO54388.1 - 1.8e-08 34.4 0.1 5.4e-08 32.8 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO54388.1 - 2.9e-07 29.8 0.0 3.5e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGO54388.1 - 0.00017 21.0 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 EGO54388.1 - 0.00035 20.6 0.1 0.002 18.1 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 EGO54388.1 - 0.00037 19.2 0.0 0.00051 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 EGO54388.1 - 0.0079 15.3 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EGO54388.1 - 0.028 14.0 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 EGO54388.1 - 0.079 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) NNMT_PNMT_TEMT PF01234.12 EGO54388.1 - 0.13 11.2 0.0 10 5.0 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family E1_dh PF00676.15 EGO54389.1 - 1.1e-84 283.7 0.0 1.5e-84 283.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EGO54389.1 - 0.0046 16.5 0.1 0.041 13.4 0.1 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Tmemb_cc2 PF10267.4 EGO54389.1 - 0.032 12.8 0.3 0.047 12.2 0.2 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SGS PF05002.10 EGO54389.1 - 0.52 10.0 2.8 2.3 8.0 0.4 2.6 2 1 1 3 3 3 0 SGS domain DUF4367 PF14285.1 EGO54390.1 - 0.00082 18.7 0.2 0.00089 18.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4367) Kei1 PF08552.6 EGO54390.1 - 0.076 12.6 1.7 0.096 12.3 1.2 1.2 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2254 PF10011.4 EGO54390.1 - 0.1 11.0 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Ubie_methyltran PF01209.13 EGO54391.1 - 1e-71 240.7 0.0 3.9e-70 235.5 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EGO54391.1 - 9.2e-12 44.8 0.0 2e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO54391.1 - 3.5e-11 43.4 0.0 9e-11 42.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO54391.1 - 4.3e-11 43.1 0.0 1.3e-09 38.4 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO54391.1 - 3.1e-09 37.1 0.0 5.4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO54391.1 - 4.7e-09 36.1 0.0 7.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO54391.1 - 2.6e-07 31.1 0.0 6.4e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO54391.1 - 2.3e-05 24.3 0.0 6.2e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EGO54391.1 - 0.02 14.4 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 Hypothetical methyltransferase ADH_zinc_N PF00107.21 EGO54391.1 - 0.097 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2Fe-2S_Ferredox PF11591.3 EGO54391.1 - 0.3 10.7 4.2 0.1 12.2 0.5 2.0 2 0 0 2 2 2 0 Ferredoxin chloroplastic transit peptide DUF2433 PF10360.4 EGO54392.1 - 5.5e-56 188.5 0.0 8.5e-56 187.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 EGO54392.1 - 0.019 14.7 0.0 0.058 13.2 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGO54392.1 - 0.037 13.4 0.0 0.089 12.1 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase DUF2360 PF10152.4 EGO54392.1 - 0.29 11.4 13.8 30 4.8 9.5 2.4 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Zds_C PF08632.5 EGO54393.1 - 3.7e-32 109.4 0.3 6.3e-32 108.7 0.2 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Peptidase_M43 PF05572.8 EGO54394.1 - 2e-11 43.7 0.0 4.4e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EGO54394.1 - 0.00032 20.7 0.1 0.00057 19.8 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EGO54394.1 - 0.00067 19.7 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EGO54394.1 - 0.0066 16.9 0.0 0.053 14.0 0.0 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EGO54394.1 - 0.02 14.6 0.0 0.032 13.9 0.0 1.5 1 1 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.1 EGO54394.1 - 0.021 14.3 0.2 0.038 13.5 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like PepSY_2 PF13670.1 EGO54394.1 - 0.12 12.2 0.6 0.27 11.1 0.4 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Amidase PF01425.16 EGO54395.1 - 1.7e-76 257.8 0.0 2.2e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 Amidase Smr PF01713.16 EGO54397.1 - 8.9e-11 41.8 0.4 2.3e-10 40.5 0.3 1.7 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 EGO54397.1 - 5.1e-08 32.2 0.0 1.1e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 CUE domain DMA PF03474.9 EGO54397.1 - 0.045 13.6 0.1 0.092 12.6 0.1 1.5 1 0 0 1 1 1 0 DMRTA motif Patched PF02460.13 EGO54398.1 - 3.5e-74 250.1 15.4 2.3e-73 247.4 10.7 1.9 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EGO54398.1 - 3.6e-49 166.1 7.1 3.6e-49 166.1 4.9 2.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EGO54398.1 - 3.2e-07 29.3 29.7 0.00028 19.7 6.4 2.7 2 0 0 2 2 2 2 MMPL family Folate_rec PF03024.9 EGO54398.1 - 0.00026 20.6 1.4 0.00055 19.6 1.0 1.5 1 0 0 1 1 1 1 Folate receptor family p450 PF00067.17 EGO54399.1 - 1.6e-63 214.8 0.0 2.1e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aha1_N PF09229.6 EGO54401.1 - 9e-39 132.4 0.7 1.4e-38 131.8 0.5 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EGO54401.1 - 5.9e-20 71.6 0.2 1.3e-19 70.5 0.2 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 EGO54401.1 - 0.00048 20.2 2.7 0.0019 18.3 0.6 2.1 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport CN_hydrolase PF00795.17 EGO54402.1 - 3.4e-20 72.1 0.0 9.3e-20 70.7 0.0 1.7 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase APH PF01636.18 EGO54403.1 - 3.8e-06 26.7 0.0 7.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGO54403.1 - 0.0023 17.5 0.0 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase FAD_binding_4 PF01565.18 EGO54404.1 - 8.3e-21 73.9 2.2 1.3e-09 37.6 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.7 EGO54404.1 - 0.022 14.6 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Berberine and berberine like F-box-like PF12937.2 EGO54405.1 - 0.096 12.4 0.0 0.38 10.5 0.0 2.1 1 1 0 1 1 1 0 F-box-like Complex1_LYR_2 PF13233.1 EGO54407.1 - 8e-19 68.0 0.0 1e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGO54407.1 - 0.0093 15.7 0.5 0.018 14.7 0.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGO54407.1 - 0.021 15.0 0.3 0.037 14.2 0.2 1.5 1 0 0 1 1 1 0 Complex1_LYR-like AraC_binding_2 PF14525.1 EGO54407.1 - 0.06 12.9 1.5 0.081 12.4 1.1 1.1 1 0 0 1 1 1 0 AraC-binding-like domain MMR_HSR1 PF01926.18 EGO54408.1 - 6.5e-21 74.4 0.0 1.2e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO54408.1 - 1.8e-10 40.5 0.0 2.9e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EGO54408.1 - 7.3e-05 22.6 3.2 0.00029 20.6 0.2 2.6 2 1 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 EGO54408.1 - 0.00023 20.4 0.1 0.015 14.5 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EGO54408.1 - 0.0023 17.1 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EGO54408.1 - 0.0063 16.8 0.1 0.015 15.5 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EGO54408.1 - 0.01 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 EGO54408.1 - 0.058 12.9 0.0 0.63 9.5 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.1 EGO54408.1 - 0.061 13.2 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 EGO54408.1 - 0.077 12.2 0.1 3.4 6.8 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Septin PF00735.13 EGO54408.1 - 0.14 11.1 0.0 0.53 9.2 0.0 1.8 1 1 0 1 1 1 0 Septin IIGP PF05049.8 EGO54408.1 - 0.19 10.4 0.1 15 4.3 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) eIF3_subunit PF08597.5 EGO54408.1 - 0.77 9.2 18.4 1.2 8.5 8.0 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit GAGA_bind PF06217.7 EGO54408.1 - 3.2 7.6 13.7 1.4 8.8 6.4 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family zf-DHHC PF01529.15 EGO54409.1 - 3.8e-34 117.5 0.7 3.8e-34 117.5 0.5 1.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase Adeno_E3_CR2 PF02439.10 EGO54409.1 - 0.45 10.0 4.1 1.2 8.7 2.9 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Myb_DNA-bind_2 PF08914.6 EGO54410.1 - 4.1e-40 135.4 14.5 4.5e-25 87.2 1.4 3.3 3 0 0 3 3 3 2 Rap1 Myb domain Rap1_C PF11626.3 EGO54410.1 - 4.4e-20 71.3 0.2 1.5e-19 69.6 0.1 2.0 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rap1-DNA-bind PF09197.5 EGO54410.1 - 2.2e-08 34.6 10.0 8.4e-05 23.0 0.1 3.7 3 0 0 3 3 3 2 Rap1, DNA-binding ARID PF01388.16 EGO54410.1 - 0.0001 22.0 0.0 0.00031 20.5 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain IQ PF00612.22 EGO54410.1 - 0.0016 17.9 3.9 0.0016 17.9 2.7 2.5 3 0 0 3 3 3 1 IQ calmodulin-binding motif Nop14 PF04147.7 EGO54410.1 - 0.078 10.9 18.2 0.17 9.7 12.6 1.5 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EGO54410.1 - 0.68 7.9 13.8 1.3 6.9 9.6 1.4 1 0 0 1 1 1 0 CDC45-like protein CEP19 PF14933.1 EGO54410.1 - 1.2 9.4 12.6 0.36 11.1 6.0 2.2 2 0 0 2 2 2 0 CEP19-like protein TRAP_alpha PF03896.11 EGO54410.1 - 4.6 6.1 15.8 9 5.1 11.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.6 EGO54410.1 - 8.2 4.4 11.0 14 3.6 7.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 UPF0560 PF10577.4 EGO54411.1 - 2.8 6.0 7.5 5.6 5.0 5.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SprA-related PF12118.3 EGO54411.1 - 2.9 7.1 21.2 0.39 10.0 11.3 1.9 2 0 0 2 2 2 0 SprA-related family MIP-T3 PF10243.4 EGO54411.1 - 6.1 5.1 35.5 1.3 7.4 21.3 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Fe-ADH PF00465.14 EGO54412.1 - 1.3e-99 333.2 0.2 1.7e-99 332.9 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EGO54412.1 - 2.7e-13 49.8 0.1 1.1e-10 41.2 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Virul_Fac PF10139.4 EGO54412.1 - 0.17 9.8 0.0 0.22 9.3 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor FAD_binding_1 PF00667.15 EGO54413.1 - 1.3e-62 211.1 0.0 3e-62 209.9 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EGO54413.1 - 1.5e-11 44.8 0.0 1.1e-10 42.0 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.13 EGO54413.1 - 2.2e-11 43.9 0.0 6e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 EGO54413.1 - 0.0061 16.4 0.4 0.026 14.4 0.3 2.1 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1-E2_ATPase PF00122.15 EGO54414.1 - 1.2e-53 181.5 1.3 9.6e-52 175.2 0.0 2.5 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.21 EGO54414.1 - 1.5e-40 139.8 4.4 8.3e-40 137.4 1.3 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EGO54414.1 - 2.6e-31 107.5 4.3 1.9e-10 40.7 0.0 5.0 5 0 0 5 5 5 4 Heavy-metal-associated domain HAD PF12710.2 EGO54414.1 - 1.1e-16 61.5 0.0 2.4e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGO54414.1 - 0.0001 21.9 0.2 0.0009 18.8 0.1 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase BCLP PF12304.3 EGO54414.1 - 0.014 14.7 0.8 0.047 13.1 0.2 2.0 2 0 0 2 2 2 0 Beta-casein like protein HAD_2 PF13419.1 EGO54414.1 - 0.046 13.9 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase zf-C3HC PF07967.8 EGO54415.1 - 1.9e-42 144.2 0.1 1e-37 128.8 0.1 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EGO54415.1 - 2.8e-29 100.7 0.6 1.1e-27 95.7 0.0 2.5 2 0 0 2 2 2 1 Rsm1-like BIR PF00653.16 EGO54415.1 - 0.00011 22.6 0.2 0.0026 18.1 0.1 2.5 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain zf-RING_4 PF14570.1 EGO54416.1 - 8.1e-15 54.1 9.5 1.6e-14 53.1 6.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EGO54416.1 - 2.4e-10 39.9 0.0 7.3e-10 38.3 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO54416.1 - 1.8e-06 27.8 0.1 6e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO54416.1 - 2.4e-05 24.0 0.1 6.6e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 EGO54416.1 - 3.6e-05 23.1 2.6 3.6e-05 23.1 1.8 3.7 3 0 0 3 3 3 1 Rtf2 RING-finger zf-C3HC4_3 PF13920.1 EGO54416.1 - 0.0022 17.6 4.2 0.0022 17.6 2.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO54416.1 - 0.0035 17.1 6.5 0.0035 17.1 4.5 1.9 2 0 0 2 2 2 1 Ring finger domain Nup35_RRM_2 PF14605.1 EGO54416.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.3 EGO54416.1 - 0.025 13.8 0.0 0.056 12.7 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Complex1_30kDa PF00329.14 EGO54417.1 - 1.1e-35 121.9 0.0 1.6e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Dioxygenase_C PF00775.16 EGO54418.1 - 7.2e-48 162.2 0.0 9.2e-48 161.9 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EGO54418.1 - 3.5e-14 52.5 0.2 5.9e-14 51.7 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EGO54418.1 - 0.024 14.6 0.0 0.12 12.4 0.0 2.2 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Lactonase PF10282.4 EGO54420.1 - 7.1e-16 58.2 0.0 9.6e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller CD4-extracel PF09191.5 EGO54420.1 - 0.15 12.0 0.0 3.4 7.7 0.0 2.2 2 0 0 2 2 2 0 CD4, extracellular SKG6 PF08693.5 EGO54421.1 - 1.2e-06 27.7 0.0 2.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 EGO54421.1 - 0.0037 16.8 2.1 0.0055 16.2 1.5 1.2 1 0 0 1 1 1 1 Podoplanin DUF4448 PF14610.1 EGO54421.1 - 0.024 14.1 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) BacteriocIIc_cy PF12173.3 EGO54421.1 - 0.47 10.5 3.0 0.5 10.4 0.8 2.0 1 1 1 2 2 2 0 Bacteriocin class IIc cyclic gassericin A-like CcoS PF03597.10 EGO54421.1 - 3.5 7.1 4.3 7.6 6.0 3.0 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Inositol_P PF00459.20 EGO54422.1 - 3.6e-45 154.3 0.6 4.8e-45 153.9 0.4 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.18 EGO54423.1 - 0.0012 19.2 0.0 0.015 15.7 0.0 2.1 1 1 1 2 2 2 1 Ribosomal protein L6 Tht1 PF04163.7 EGO54424.1 - 7.1e-06 24.6 2.6 7.1e-06 24.6 1.8 1.7 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein DUF3552 PF12072.3 EGO54424.1 - 0.58 9.3 14.1 2 7.5 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DASH_Dad2 PF08654.5 EGO54424.1 - 0.72 9.8 7.2 0.86 9.6 0.4 2.8 2 1 0 2 2 2 0 DASH complex subunit Dad2 Tropomyosin_1 PF12718.2 EGO54424.1 - 0.93 9.3 17.9 0.34 10.7 2.6 2.6 2 1 0 2 2 2 0 Tropomyosin like XhlA PF10779.4 EGO54424.1 - 2.4 8.1 8.2 11 5.9 0.5 2.8 2 0 0 2 2 2 0 Haemolysin XhlA DUF1993 PF09351.5 EGO54424.1 - 4.1 7.3 12.2 1.6 8.6 1.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) DUF3450 PF11932.3 EGO54424.1 - 5.6 6.1 21.4 4 6.6 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.7 EGO54424.1 - 8.3 6.7 18.6 10 6.4 2.9 3.4 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Muted PF14942.1 EGO54424.1 - 9.5 6.0 13.6 18 5.1 1.8 3.3 1 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein Reo_sigmaC PF04582.7 EGO54424.1 - 9.7 5.2 11.6 6.4 5.8 5.7 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GSDH PF07995.6 EGO54425.1 - 0.05 12.6 1.0 0.32 10.0 0.1 2.6 3 1 1 4 4 4 0 Glucose / Sorbosone dehydrogenase SGL PF08450.7 EGO54425.1 - 0.067 12.5 0.6 9.3 5.5 0.0 2.3 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Ion_trans_2 PF07885.11 EGO54426.1 - 3.3e-31 106.8 19.4 1.5e-18 66.2 2.4 2.9 4 0 0 4 4 4 2 Ion channel Tox-HNH-EHHH PF15657.1 EGO54426.1 - 0.0039 17.3 0.1 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 HNH/Endo VII superfamily nuclease toxins Ion_trans PF00520.26 EGO54426.1 - 0.58 9.3 16.1 0.37 10.0 0.4 2.9 2 1 1 3 3 3 0 Ion transport protein WD40 PF00400.27 EGO54428.1 - 3.8e-47 156.5 20.2 2e-11 43.2 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EGO54428.1 - 1.7e-07 31.0 12.4 0.02 14.5 0.2 4.4 2 2 2 4 4 4 3 Transcription factor IIIC subunit delta N-term YmzC PF14157.1 EGO54428.1 - 0.0023 17.7 0.0 0.6 9.9 0.0 3.5 3 0 0 3 3 3 1 YmzC-like protein Kelch_6 PF13964.1 EGO54428.1 - 0.051 13.7 0.3 1.2 9.4 0.0 3.0 3 0 0 3 3 3 0 Kelch motif IKI3 PF04762.7 EGO54428.1 - 1.1 7.0 3.8 7.8 4.1 0.6 2.1 2 0 0 2 2 2 0 IKI3 family DUF4407 PF14362.1 EGO54429.1 - 3.5 6.5 8.2 5.1 5.9 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DOPA_dioxygen PF08883.6 EGO54431.1 - 1e-26 93.0 0.3 4.3e-25 87.7 0.2 2.1 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family SKG6 PF08693.5 EGO54432.1 - 0.015 14.6 0.3 0.03 13.6 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EGO54432.1 - 0.073 13.4 0.0 0.21 12.0 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Plasmodium_Vir PF05795.6 EGO54432.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1631 PF07793.6 EGO54432.1 - 0.45 8.5 0.1 0.57 8.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) AF-4 PF05110.8 EGO54432.1 - 5.8 4.6 8.2 10 3.8 5.7 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein bZIP_1 PF00170.16 EGO54433.1 - 5.2e-05 23.1 6.7 0.0001 22.1 4.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGO54433.1 - 0.0012 18.5 6.4 0.0022 17.7 4.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper MCM2_N PF12619.3 EGO54433.1 - 0.26 11.2 3.0 0.43 10.5 2.1 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 Tubulin PF00091.20 EGO54435.1 - 1.6e-70 237.3 0.0 2.8e-70 236.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGO54435.1 - 4.1e-49 165.8 0.1 6.3e-49 165.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EGO54435.1 - 1.2e-05 25.3 0.0 2.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EGO54435.1 - 0.0033 16.9 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain ABC_tran PF00005.22 EGO54437.1 - 1.1e-48 165.0 0.3 8.6e-23 81.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EGO54437.1 - 7.4e-21 73.8 5.0 7.4e-21 73.8 3.5 4.1 4 1 0 4 4 2 1 ABC transporter AAA_21 PF13304.1 EGO54437.1 - 2.1e-17 64.0 0.0 0.00027 20.9 0.0 4.4 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 EGO54437.1 - 1.2e-11 44.2 0.5 0.0084 15.3 0.0 4.5 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EGO54437.1 - 4.8e-10 40.2 1.1 0.0013 19.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 EGO54437.1 - 4.5e-08 32.5 0.7 0.2 10.6 0.0 4.3 4 0 0 4 4 4 2 AAA ATPase domain AAA_18 PF13238.1 EGO54437.1 - 1.8e-07 31.5 2.2 0.01 16.1 0.0 3.8 4 1 0 4 4 2 2 AAA domain AAA_29 PF13555.1 EGO54437.1 - 5.4e-07 29.0 0.1 0.014 14.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGO54437.1 - 1.3e-06 28.3 0.1 0.011 15.6 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase Miro PF08477.8 EGO54437.1 - 2.4e-06 28.0 0.1 0.027 14.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EGO54437.1 - 1.1e-05 25.5 1.3 0.0065 16.4 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 EGO54437.1 - 1.3e-05 25.1 0.0 0.056 13.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGO54437.1 - 1.7e-05 24.0 0.0 0.031 13.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGO54437.1 - 2e-05 24.7 0.0 0.33 11.0 0.0 3.1 3 1 0 3 3 2 2 AAA domain MobB PF03205.9 EGO54437.1 - 5.1e-05 22.9 0.4 0.3 10.7 0.2 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EGO54437.1 - 7.2e-05 22.7 2.2 0.036 14.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.1 EGO54437.1 - 0.00012 22.4 0.2 0.0055 17.0 0.0 4.4 5 0 0 5 5 4 2 AAA domain AAA PF00004.24 EGO54437.1 - 0.00014 22.1 0.1 0.38 10.9 0.1 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EGO54437.1 - 0.00035 20.4 3.0 0.69 9.7 0.0 3.8 4 0 0 4 4 4 1 Dynamin family AAA_14 PF13173.1 EGO54437.1 - 0.00084 19.2 0.1 2.4 8.0 0.0 3.3 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 EGO54437.1 - 0.0018 17.9 0.3 2.4 7.7 0.1 2.6 2 0 0 2 2 2 2 NACHT domain ArgK PF03308.11 EGO54437.1 - 0.0022 16.8 1.9 0.61 8.8 0.0 2.7 3 0 0 3 3 2 2 ArgK protein ATP-synt_ab PF00006.20 EGO54437.1 - 0.0036 16.8 0.1 0.49 9.8 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 EGO54437.1 - 0.0037 16.9 0.1 0.7 9.5 0.1 2.7 2 0 0 2 2 2 1 NTPase AAA_25 PF13481.1 EGO54437.1 - 0.0039 16.6 0.0 2.2 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EGO54437.1 - 0.004 16.6 1.8 2.9 7.2 0.2 3.7 4 0 0 4 4 4 1 AAA-like domain SbcCD_C PF13558.1 EGO54437.1 - 0.0047 16.8 0.4 3 7.8 0.1 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit cobW PF02492.14 EGO54437.1 - 0.011 15.2 0.8 3.1 7.2 0.5 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EGO54437.1 - 0.013 15.2 0.2 5.1 6.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EGO54437.1 - 0.016 15.4 0.0 8 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 EGO54437.1 - 0.017 13.9 0.0 5.2 5.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain SRP54 PF00448.17 EGO54437.1 - 0.037 13.4 1.0 3.2 7.1 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain GTP_EFTU PF00009.22 EGO54437.1 - 0.06 12.7 2.4 9.5 5.6 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EGO54437.1 - 0.073 12.5 0.0 16 4.9 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 EGO54437.1 - 0.08 12.1 0.1 1.2 8.3 0.1 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family ATP_bind_1 PF03029.12 EGO54437.1 - 0.14 11.6 1.0 24 4.3 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.16 EGO54437.1 - 0.23 10.5 1.6 36 3.4 0.1 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_13 PF13166.1 EGO54437.1 - 3.5 5.9 12.5 14 3.9 0.0 4.1 4 1 0 4 4 4 0 AAA domain DUF87 PF01935.12 EGO54437.1 - 3.8 7.2 9.5 2.1 8.1 0.1 3.5 4 0 0 4 4 3 0 Domain of unknown function DUF87 bZIP_1 PF00170.16 EGO54438.1 - 2.6e-13 49.7 3.7 3.7e-13 49.2 2.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGO54438.1 - 0.00019 21.1 9.9 0.00038 20.2 6.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper PAT1 PF09770.4 EGO54438.1 - 0.034 12.4 5.3 0.037 12.2 3.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 bZIP_Maf PF03131.12 EGO54438.1 - 0.075 13.3 1.3 0.075 13.3 0.9 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor MIS13 PF08202.6 EGO54438.1 - 2.1 7.3 6.8 0.73 8.8 0.2 2.2 2 0 0 2 2 2 0 Mis12-Mtw1 protein family A_deaminase PF00962.17 EGO54440.1 - 3.5e-44 151.0 0.4 1.5e-43 148.9 0.3 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 EGO54440.1 - 0.012 15.6 0.1 0.049 13.6 0.0 2.0 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal SRP40_C PF05022.7 EGO54441.1 - 1.7e-26 92.4 0.6 1.7e-26 92.4 0.4 2.4 2 0 0 2 2 2 1 SRP40, C-terminal domain 7tm_1 PF00001.16 EGO54443.1 - 0.021 13.9 0.0 0.038 13.1 0.0 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF3169 PF11368.3 EGO54443.1 - 0.032 13.4 0.2 0.032 13.4 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) DUF2763 PF10961.3 EGO54444.1 - 9.1 6.7 10.5 15 6.0 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) Complex1_51K PF01512.12 EGO54445.1 - 8.4e-47 158.6 0.0 1.3e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EGO54445.1 - 3.5e-18 64.4 0.9 3.5e-18 64.4 0.7 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EGO54445.1 - 3.5e-09 36.4 0.0 9.8e-09 34.9 0.0 1.8 1 0 0 1 1 1 1 SLBB domain Hexapep PF00132.19 EGO54447.1 - 6.1e-08 31.8 16.5 1.7e-06 27.2 3.1 4.1 5 2 0 5 5 5 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGO54447.1 - 0.00029 20.3 10.0 0.53 9.8 3.4 3.7 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase PFL PF02901.10 EGO54447.1 - 0.18 10.1 0.0 0.24 9.7 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase Flavoprotein PF02441.14 EGO54448.1 - 7.4e-17 61.2 0.0 1.7e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Flavoprotein Ank_5 PF13857.1 EGO54448.1 - 0.00056 20.0 0.0 1 9.7 0.0 3.6 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGO54448.1 - 0.00071 20.0 0.0 1.5 9.4 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO54448.1 - 0.00098 19.4 0.0 0.033 14.5 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGO54448.1 - 0.046 13.9 0.0 3.6 8.0 0.0 3.3 4 0 0 4 4 4 0 Ankyrin repeat Ank PF00023.25 EGO54448.1 - 0.15 11.9 0.0 7.7 6.5 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat DEAD PF00270.24 EGO54450.1 - 8.4e-38 129.5 0.1 2.6e-37 127.9 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO54450.1 - 1.6e-22 79.1 0.0 3.9e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGO54450.1 - 1.9e-05 23.5 0.0 4.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_19 PF13245.1 EGO54450.1 - 0.029 14.1 1.3 0.19 11.4 0.0 2.8 3 0 0 3 3 3 0 Part of AAA domain Daxx PF03344.10 EGO54450.1 - 0.25 9.7 37.7 0.54 8.6 9.6 2.4 2 0 0 2 2 2 0 Daxx Family CDC45 PF02724.9 EGO54450.1 - 2.1 6.2 34.6 0.069 11.1 5.3 2.5 3 0 0 3 3 3 0 CDC45-like protein SAPS PF04499.10 EGO54450.1 - 4.2 5.8 17.6 2 6.9 4.3 2.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein FtsJ PF01728.14 EGO54451.1 - 4.9e-61 205.8 0.0 6.4e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Gly_transf_sug PF04488.10 EGO54453.1 - 9e-09 35.6 0.0 2.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EGO54453.1 - 3.6e-05 22.4 0.0 5e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EGO54453.1 - 0.0008 18.6 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Glyco_transf_15 PF01793.11 EGO54454.1 - 2.1e-121 404.9 6.5 2.6e-121 404.6 4.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SLY PF12485.3 EGO54455.1 - 0.29 11.3 8.0 0.38 10.9 5.5 1.2 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein RR_TM4-6 PF06459.7 EGO54455.1 - 5.9 6.6 12.6 6.6 6.5 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hira PF07569.6 EGO54456.1 - 3.8e-85 284.5 0.0 1e-84 283.1 0.0 1.8 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EGO54456.1 - 5.3e-43 143.3 17.5 3.7e-07 29.7 0.1 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat HIRA_B PF09453.5 EGO54456.1 - 1.3e-11 43.6 1.0 3.3e-11 42.4 0.7 1.8 1 0 0 1 1 1 1 HIRA B motif eIF2A PF08662.6 EGO54456.1 - 0.00014 21.6 0.5 0.85 9.2 0.0 4.2 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EGO54456.1 - 0.00017 21.1 0.5 38 4.0 0.0 5.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EGO54456.1 - 0.048 12.7 0.2 3.3 6.7 0.0 2.7 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Rav1p_C PF12234.3 EGO54456.1 - 0.38 8.8 0.0 4.7 5.2 0.0 2.0 2 0 0 2 2 2 0 RAVE protein 1 C terminal MARVEL PF01284.18 EGO54458.1 - 8.3e-09 35.4 9.8 8.3e-09 35.4 6.8 1.9 1 1 0 2 2 2 1 Membrane-associating domain DUF588 PF04535.7 EGO54458.1 - 0.00037 20.0 1.8 0.0007 19.1 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF588) RDD PF06271.7 EGO54458.1 - 0.11 12.4 4.1 0.066 13.1 1.4 1.6 1 1 1 2 2 2 0 RDD family TFIIA PF03153.8 EGO54458.1 - 5.1 6.8 19.3 7 6.4 13.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIR PF00399.14 EGO54459.1 - 1.4 8.3 11.7 2.6 7.5 0.6 3.0 2 0 0 2 2 2 0 Yeast PIR protein repeat zf-U1 PF06220.7 EGO54460.1 - 3.8e-09 35.9 0.2 6.2e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 U1 zinc finger GAF_2 PF13185.1 EGO54460.1 - 0.019 15.4 0.4 0.041 14.3 0.3 1.5 1 0 0 1 1 1 0 GAF domain DUF3245 PF11595.3 EGO54460.1 - 0.73 10.1 15.4 0.25 11.6 7.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Elongin_A PF06881.6 EGO54461.1 - 9.5 6.6 9.1 3.3 8.1 2.3 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Glycos_transf_1 PF00534.15 EGO54462.1 - 2.1e-11 43.5 0.0 6.6e-11 41.9 0.0 1.8 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGO54462.1 - 1.9e-07 31.3 0.0 4.5e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 PNPOx_C PF10590.4 EGO54462.1 - 0.069 12.6 0.3 0.16 11.4 0.2 1.7 1 1 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region TM231 PF10149.4 EGO54462.1 - 0.081 11.9 0.0 0.62 9.0 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 231 CENP-H PF05837.7 EGO54463.1 - 0.016 15.3 1.5 0.016 15.3 1.0 3.9 3 1 1 4 4 4 0 Centromere protein H (CENP-H) DUF1777 PF08648.7 EGO54463.1 - 0.26 11.0 24.5 0.3 10.7 9.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Glyco_hydro_7 PF00840.15 EGO54464.1 - 3.8e-79 266.0 0.6 1.1e-42 145.9 0.1 3.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 7 Lustrin_cystein PF14625.1 EGO54464.1 - 0.61 10.2 5.7 0.92 9.6 0.8 2.5 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain HECT PF00632.20 EGO54468.1 - 8.4e-65 218.9 0.0 1.6e-64 218.0 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-C2H2_2 PF12756.2 EGO54469.1 - 4.7e-37 126.1 6.8 7.7e-29 99.7 0.3 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EGO54469.1 - 1e-11 44.5 12.4 2.3e-07 30.7 3.1 4.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGO54469.1 - 4.3e-06 26.7 8.8 2.2e-05 24.4 2.6 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EGO54469.1 - 0.0002 21.5 16.9 2.1 8.8 0.9 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type Stc1 PF12898.2 EGO54469.1 - 0.0077 16.2 0.9 1.8 8.6 0.1 2.8 2 0 0 2 2 2 1 Stc1 domain zf-DBF PF07535.7 EGO54469.1 - 0.026 14.2 5.0 0.13 11.9 0.2 3.2 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2_6 PF13912.1 EGO54469.1 - 0.043 13.7 2.6 1.4 8.9 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger DUF629 PF04780.7 EGO54469.1 - 0.085 11.3 0.0 0.17 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF629) ABC_tran PF00005.22 EGO54470.1 - 2.5e-46 157.3 0.2 4.2e-25 88.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EGO54470.1 - 9.9e-33 113.5 39.7 1.4e-21 76.8 16.5 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EGO54470.1 - 2.7e-22 80.0 1.4 3.1e-05 24.1 0.0 4.3 3 1 0 4 4 4 4 AAA domain AAA_29 PF13555.1 EGO54470.1 - 2.1e-09 36.7 0.9 0.0018 17.7 0.2 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.14 EGO54470.1 - 5e-06 25.9 3.2 1.6 7.8 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGO54470.1 - 6e-06 26.7 2.9 0.035 14.4 0.3 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGO54470.1 - 0.00052 20.0 0.8 1.5 8.7 0.2 3.0 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EGO54470.1 - 0.00083 18.5 2.8 0.41 9.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EGO54470.1 - 0.0012 17.9 0.0 2.7 6.9 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 EGO54470.1 - 0.0016 17.8 0.0 2.1 7.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGO54470.1 - 0.0017 18.0 6.1 2.1 8.1 0.4 4.7 4 0 0 4 4 4 1 Part of AAA domain DUF4162 PF13732.1 EGO54470.1 - 0.0029 18.0 0.0 0.58 10.6 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_22 PF13401.1 EGO54470.1 - 0.05 13.7 0.3 7.4 6.7 0.1 2.8 2 0 0 2 2 2 0 AAA domain MutS_V PF00488.16 EGO54470.1 - 0.07 12.5 0.4 2.4 7.4 0.0 2.7 3 0 0 3 3 3 0 MutS domain V AAA_13 PF13166.1 EGO54470.1 - 0.076 11.4 0.0 2.4 6.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGO54470.1 - 0.12 12.2 0.3 33 4.3 0.1 3.1 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.10 EGO54470.1 - 0.14 10.7 0.0 4.6 5.7 0.0 2.5 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein SRP54 PF00448.17 EGO54470.1 - 0.17 11.3 1.9 11 5.4 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain G-alpha PF00503.15 EGO54470.1 - 0.56 8.8 0.0 3.8 6.1 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit AAA_10 PF12846.2 EGO54470.1 - 1.2 8.4 4.6 31 3.8 0.3 3.5 3 1 1 4 4 4 0 AAA-like domain tRNA-synt_2 PF00152.15 EGO54471.1 - 3e-85 285.9 1.1 4.1e-85 285.5 0.8 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGO54471.1 - 2.7e-11 43.1 0.0 5.4e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGO54471.1 - 2.2e-10 40.1 0.3 2e-05 23.9 0.0 3.0 2 1 1 3 3 3 2 tRNA synthetases class II core domain (F) CTP_transf_2 PF01467.21 EGO54472.1 - 3.7e-24 85.5 0.0 7e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase DUF3620 PF12281.3 EGO54472.1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3620) HALZ PF02183.13 EGO54474.1 - 0.036 13.7 1.6 0.081 12.6 1.1 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper zf-ribbon_3 PF13248.1 EGO54474.1 - 0.13 11.5 0.2 0.27 10.5 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DivIC PF04977.10 EGO54474.1 - 0.48 9.9 3.4 1.1 8.7 2.3 1.5 1 0 0 1 1 1 0 Septum formation initiator Atg14 PF10186.4 EGO54474.1 - 0.5 9.2 5.8 0.9 8.4 4.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Daxx PF03344.10 EGO54474.1 - 8.6 4.6 21.0 17 3.7 14.6 1.4 1 0 0 1 1 1 0 Daxx Family Chromo PF00385.19 EGO54475.1 - 4.3e-13 48.7 0.8 4.3e-13 48.7 0.6 2.5 2 1 1 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EGO54475.1 - 1.7e-10 40.5 0.0 4e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Chromo shadow domain AT_hook PF02178.14 EGO54475.1 - 0.058 13.0 0.5 0.16 11.6 0.4 1.8 1 0 0 1 1 1 0 AT hook motif His_Phos_1 PF00300.17 EGO54477.1 - 1.9e-14 54.0 1.4 4.1e-13 49.7 0.1 2.3 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF2502 PF10697.4 EGO54477.1 - 5.4 7.1 9.0 0.091 12.8 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2502) VHS PF00790.14 EGO54478.1 - 8.3e-43 145.3 1.1 1.6e-41 141.2 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EGO54478.1 - 1.8e-15 56.5 5.4 3.8e-15 55.5 3.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EGO54478.1 - 8.4e-05 21.8 16.1 0.0031 16.9 0.8 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-DHHC PF01529.15 EGO54478.1 - 0.0013 18.1 0.9 0.0033 16.8 0.7 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ribosomal_S30AE PF02482.14 EGO54478.1 - 0.075 13.4 0.8 0.27 11.6 0.6 2.0 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein UCH PF00443.24 EGO54479.1 - 3.3e-38 131.3 0.0 4.5e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO54479.1 - 2e-14 53.7 0.0 3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EGO54479.1 - 6.4e-05 23.2 0.0 0.00017 21.9 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain USP8_dimer PF08969.6 EGO54479.1 - 0.0044 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain Aldedh PF00171.17 EGO54480.1 - 3.6e-83 279.4 0.0 4.4e-83 279.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_transf_90 PF05686.7 EGO54481.1 - 2.9e-16 59.1 0.0 2.6e-13 49.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 zf-ZPR1 PF03367.8 EGO54481.1 - 0.22 10.6 0.0 0.41 9.8 0.0 1.4 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Acyl_transf_1 PF00698.16 EGO54482.1 - 8.1e-20 71.3 0.1 1.9e-13 50.4 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain ECR1_N PF14382.1 EGO54483.1 - 2.6e-11 42.6 0.0 5.2e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EGO54483.1 - 0.0004 20.2 0.1 0.0025 17.7 0.1 2.2 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 EGO54483.1 - 0.0011 18.9 0.4 1.5 8.9 0.0 3.5 3 0 0 3 3 3 2 S1 RNA binding domain AFG1_ATPase PF03969.11 EGO54484.1 - 8.7e-55 185.9 0.2 2.6e-25 89.0 0.0 4.8 3 2 2 5 5 5 4 AFG1-like ATPase AAA_5 PF07728.9 EGO54484.1 - 1.6e-05 24.6 0.0 3.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EGO54484.1 - 0.00087 19.5 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGO54484.1 - 0.002 18.1 1.1 0.027 14.4 0.1 2.7 1 1 2 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EGO54484.1 - 0.0027 17.8 0.1 0.02 15.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.22 EGO54484.1 - 0.0046 17.2 0.2 3.8 7.7 0.1 2.6 1 1 1 2 2 2 2 ABC transporter AAA_14 PF13173.1 EGO54484.1 - 0.043 13.7 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain EVC2_like PF12297.3 EGO54484.1 - 0.065 11.8 0.1 0.1 11.2 0.1 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein NACHT PF05729.7 EGO54484.1 - 0.07 12.7 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 EGO54484.1 - 0.12 11.9 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.9 EGO54484.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain DUF4149 PF13664.1 EGO54484.1 - 0.15 12.1 0.1 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) PIF1 PF05970.9 EGO54484.1 - 0.2 10.5 0.0 0.36 9.7 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Nucleoporin_C PF03177.9 EGO54485.1 - 1.2e-112 377.3 10.2 1.5e-112 377.0 7.1 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EGO54485.1 - 6.3e-99 331.5 0.0 8.3e-99 331.1 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.20 EGO54487.1 - 1.6e-36 125.7 0.0 2.1e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO54487.1 - 8.8e-15 54.4 0.0 1.5e-14 53.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGO54487.1 - 0.01 15.6 0.0 0.43 10.2 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF605 PF04652.11 EGO54487.1 - 0.07 12.5 12.8 0.087 12.2 8.9 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EGO54487.1 - 8.9 4.4 18.2 12 3.9 12.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EMP24_GP25L PF01105.19 EGO54488.1 - 8.2e-53 178.8 0.0 9.3e-53 178.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PspB PF06667.7 EGO54488.1 - 0.085 12.8 0.5 0.17 11.8 0.3 1.5 1 0 0 1 1 1 0 Phage shock protein B Disaggr_repeat PF06848.6 EGO54488.1 - 0.094 12.1 0.2 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 Disaggregatase related repeat Hexapep PF00132.19 EGO54491.1 - 5.2e-12 44.6 18.3 3.5e-09 35.7 1.8 3.7 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EGO54491.1 - 2.8e-11 43.2 0.0 6.1e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 EGO54491.1 - 3.2e-10 39.4 15.6 9.1e-06 25.1 1.2 2.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.13 EGO54491.1 - 3.4e-09 36.4 10.3 6.8e-09 35.4 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2722 PF10846.3 EGO54492.1 - 0.056 12.4 0.3 0.046 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Adap_comp_sub PF00928.16 EGO54493.1 - 2.9e-74 249.5 0.0 5.5e-74 248.5 0.0 1.5 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGO54493.1 - 9.3e-05 22.1 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4536 PF15055.1 EGO54494.1 - 4.3e-05 23.4 0.3 7.2e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) Coiled-coil_56 PF09813.4 EGO54494.1 - 0.045 13.7 0.0 5.6 7.0 0.0 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 Glyco_hydro_6 PF01341.12 EGO54496.1 - 1.8e-99 332.9 0.4 2.3e-99 332.5 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 OST3_OST6 PF04756.8 EGO54497.1 - 3.3e-20 72.2 1.2 5.3e-20 71.6 0.8 1.3 1 0 0 1 1 1 1 OST3 / OST6 family DUF4535 PF15054.1 EGO54497.1 - 0.00076 18.8 0.2 0.0017 17.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4535) Thioredoxin PF00085.15 EGO54497.1 - 0.043 13.4 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin NADH-u_ox-rdase PF10785.4 EGO54497.1 - 0.3 11.3 3.3 0.63 10.3 0.1 2.9 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit GAS PF13851.1 EGO54498.1 - 4.4 6.4 80.4 0.33 10.1 15.9 3.4 1 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding Ank_2 PF12796.2 EGO54499.1 - 2.7e-05 24.4 0.0 4.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGO54499.1 - 0.00032 20.3 0.0 0.001 18.7 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 EGO54499.1 - 0.0018 18.2 0.0 0.0052 16.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat zf-RING_4 PF14570.1 EGO54499.1 - 0.017 14.7 1.1 0.017 14.7 0.8 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 EGO54499.1 - 0.018 14.8 4.5 0.038 13.8 3.1 1.5 1 0 0 1 1 1 0 Ring finger domain Ank_4 PF13637.1 EGO54499.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) zf-C3HC4_2 PF13923.1 EGO54499.1 - 0.16 12.0 5.7 0.15 12.1 2.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EGO54499.1 - 0.58 10.1 3.9 1.2 9.1 2.7 1.5 1 0 0 1 1 1 0 RING-like domain CH PF00307.26 EGO54500.1 - 5.1e-59 196.9 0.0 6.3e-16 58.3 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EGO54500.1 - 2.8e-05 24.1 0.1 0.0015 18.6 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 EGO54500.1 - 0.0025 16.9 0.7 0.39 10.1 0.2 3.3 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 EGO54500.1 - 0.013 15.2 0.7 0.22 11.4 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain CAMSAP_CH PF11971.3 EGO54500.1 - 0.091 12.4 0.0 21 4.8 0.0 2.8 2 0 0 2 2 2 0 CAMSAP CH domain MBOAT PF03062.14 EGO54501.1 - 2.6e-41 141.7 23.9 8.5e-41 140.1 14.3 2.3 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EGO54501.1 - 2.8e-06 27.3 6.0 8.1e-06 25.8 4.1 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF2217 PF10265.4 EGO54501.1 - 0.11 11.2 0.1 2.5 6.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) RRM_1 PF00076.17 EGO54502.1 - 1.2e-11 44.0 0.0 1.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO54502.1 - 6.7e-08 32.3 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO54502.1 - 1.1e-07 31.5 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGO54502.1 - 0.00035 20.2 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 EGO54502.1 - 9.2 4.6 19.2 12 4.2 13.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mito_carr PF00153.22 EGO54503.1 - 2.9e-76 251.2 1.8 4e-27 93.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18e PF00828.14 EGO54504.1 - 2.8e-26 92.3 0.3 2.8e-26 92.3 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 DDHD PF02862.12 EGO54505.1 - 1.2e-80 270.5 0.1 1.2e-80 270.5 0.1 4.3 3 1 0 3 3 3 1 DDHD domain FtsJ PF01728.14 EGO54505.1 - 5.2e-55 186.2 3.6 2e-54 184.3 2.5 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase DUF2305 PF10230.4 EGO54505.1 - 0.068 12.5 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) RNA_pol_Rpb1_5 PF04998.12 EGO54506.1 - 4e-88 295.2 0.1 7e-88 294.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EGO54506.1 - 1.7e-67 228.0 0.0 3.1e-67 227.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EGO54506.1 - 1.6e-53 181.0 0.0 4.4e-53 179.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EGO54506.1 - 2.7e-35 121.4 0.0 5.5e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EGO54506.1 - 6.5e-30 103.0 0.1 1.8e-29 101.6 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 TRM13 PF05206.9 EGO54506.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase TRM13 DUF159 PF02586.9 EGO54507.1 - 5.9e-61 205.6 0.0 9.1e-61 205.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Pol_alpha_B_N PF08418.5 EGO54507.1 - 0.33 10.4 3.6 0.58 9.6 2.5 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF3401 PF11881.3 EGO54508.1 - 0.0056 16.1 0.6 0.0089 15.4 0.4 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3401) Macoilin PF09726.4 EGO54508.1 - 0.045 12.0 9.7 0.04 12.2 6.7 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF2457 PF10446.4 EGO54508.1 - 0.18 10.5 5.0 0.26 9.9 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.6 EGO54508.1 - 0.32 8.8 7.4 0.43 8.3 5.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 EGO54508.1 - 0.71 9.6 22.8 1 9.1 15.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF566 PF04484.7 EGO54508.1 - 3.3 7.1 8.9 4.3 6.7 6.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF506 PF04720.7 EGO54508.1 - 4 7.0 6.3 6 6.4 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Peptidase_S64 PF08192.6 EGO54508.1 - 6 5.0 11.6 6.3 5.0 8.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Utp14 PF04615.8 EGO54508.1 - 8.8 4.3 13.6 12 3.9 9.5 1.2 1 0 0 1 1 1 0 Utp14 protein HSP70 PF00012.15 EGO54511.1 - 7.7e-272 902.6 13.7 8.8e-272 902.4 9.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGO54511.1 - 6e-18 64.5 1.5 2.3e-16 59.2 0.4 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.5 EGO54511.1 - 0.0033 16.3 0.2 0.039 12.7 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EGO54511.1 - 0.013 14.6 5.3 0.077 12.0 0.1 3.1 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 EGO54511.1 - 0.46 10.3 7.7 4.2 7.2 0.1 3.8 3 1 0 3 3 3 0 Cell division protein FtsA GTP_EFTU PF00009.22 EGO54512.1 - 1.3e-47 161.6 0.0 2.4e-47 160.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EGO54512.1 - 4.4e-21 74.7 0.5 1.1e-20 73.5 0.3 1.7 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 EGO54512.1 - 1.2e-08 35.0 0.2 6.5e-08 32.6 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 EGO54512.1 - 7.3e-07 29.1 0.0 3.3e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGO54512.1 - 4e-05 24.1 0.1 0.0022 18.4 0.0 2.7 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 EGO54512.1 - 7.9e-05 22.6 0.2 0.00029 20.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 SRPRB PF09439.5 EGO54512.1 - 0.013 14.6 0.0 2.6 7.2 0.0 2.5 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Ras PF00071.17 EGO54512.1 - 0.019 14.3 0.1 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 Ras family Arf PF00025.16 EGO54512.1 - 0.026 13.7 0.1 4.8 6.3 0.1 2.5 1 1 1 2 2 2 0 ADP-ribosylation factor family FeoB_N PF02421.13 EGO54512.1 - 0.077 12.2 0.0 1 8.5 0.0 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B Cpn60_TCP1 PF00118.19 EGO54513.1 - 1.3e-146 489.0 2.7 1.6e-146 488.8 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 EGO54513.1 - 0.083 12.8 1.8 28 4.6 0.0 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain BATS PF06968.8 EGO54514.1 - 1.1e-25 89.2 0.0 3.5e-25 87.6 0.0 1.8 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EGO54514.1 - 1.2e-14 54.8 0.1 1.9e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily COesterase PF00135.23 EGO54515.1 - 3.5e-66 224.0 0.0 5e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO54515.1 - 1.9e-06 27.6 0.2 9e-06 25.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Med3 PF11593.3 EGO54516.1 - 0.51 9.5 5.0 0.8 8.8 3.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-C2H2 PF00096.21 EGO54518.1 - 1.4e-21 75.4 24.4 1.3e-05 25.2 1.2 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO54518.1 - 1.8e-21 75.2 25.6 2.3e-07 30.7 0.4 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO54518.1 - 2e-15 55.8 24.6 0.00034 20.7 2.6 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO54518.1 - 0.0012 18.9 9.2 4.1 7.6 0.1 4.9 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGO54518.1 - 0.01 15.7 13.8 0.63 10.0 0.4 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger C1_4 PF07975.7 EGO54518.1 - 0.029 14.3 0.2 3.5 7.7 0.0 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.5 EGO54518.1 - 0.11 12.4 10.1 3.5 7.6 1.0 3.7 3 1 0 3 3 3 0 Zinc ribbon domain zf-met PF12874.2 EGO54518.1 - 0.19 11.9 13.1 6.2 7.1 0.5 4.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type DUF2072 PF09845.4 EGO54518.1 - 0.24 11.3 1.8 0.53 10.2 1.3 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) C1_1 PF00130.17 EGO54518.1 - 8.2 6.2 7.5 1.8 8.3 1.4 2.3 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Reo_sigmaC PF04582.7 EGO54519.1 - 0.00035 19.8 33.6 0.0074 15.5 2.9 5.4 1 1 5 6 6 6 5 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EGO54519.1 - 0.00064 19.4 6.5 0.00064 19.4 4.5 10.0 3 3 8 11 11 11 4 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 EGO54519.1 - 0.0012 18.6 14.6 0.0012 18.6 10.1 6.3 2 2 3 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 EGO54519.1 - 0.006 16.3 0.7 0.006 16.3 0.5 7.9 2 2 6 9 9 9 4 Protein of unknown function (DUF1664) AAA_13 PF13166.1 EGO54519.1 - 4.4 5.6 83.2 0.35 9.2 8.1 4.6 1 1 4 5 5 5 0 AAA domain Ribosomal_L33 PF00471.15 EGO54520.1 - 1.3e-06 28.5 0.0 1.6e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 DUF412 PF04217.8 EGO54520.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF412 Aminotran_1_2 PF00155.16 EGO54522.1 - 8.3e-39 133.5 0.0 1.1e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4350 PF14258.1 EGO54522.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) RPN7 PF10602.4 EGO54523.1 - 1.2e-56 190.8 1.3 1.8e-56 190.3 0.3 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 EGO54523.1 - 3.2e-14 53.1 0.0 7.2e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 PCI domain BEX PF04538.7 EGO54523.1 - 0.29 11.3 2.6 0.55 10.4 1.8 1.4 1 0 0 1 1 1 0 Brain expressed X-linked like family Pox_MCEL PF03291.11 EGO54524.1 - 2.9e-65 220.3 0.0 1.2e-44 152.5 0.0 2.4 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 EGO54524.1 - 3.3e-08 33.9 0.0 0.0026 18.1 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EGO54524.1 - 1.2e-06 28.8 0.0 0.036 14.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EGO54524.1 - 2.4e-06 28.0 0.0 5.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO54524.1 - 3.5e-06 26.8 0.0 8.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO54524.1 - 5.7e-06 26.6 0.0 1.4e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO54524.1 - 0.00012 21.6 0.0 0.0075 15.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Raftlin PF15250.1 EGO54524.1 - 0.0002 20.0 0.2 0.0002 20.0 0.1 2.1 2 0 0 2 2 2 1 Raftlin NNMT_PNMT_TEMT PF01234.12 EGO54524.1 - 0.00036 19.5 0.0 0.00067 18.6 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family SAPS PF04499.10 EGO54524.1 - 0.019 13.6 1.4 0.28 9.7 0.0 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Flavokinase PF01687.12 EGO54525.1 - 7e-36 122.8 0.0 8.5e-36 122.5 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase FimP PF09766.4 EGO54525.1 - 0.023 13.7 2.9 0.03 13.4 2.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein PAT1 PF09770.4 EGO54525.1 - 0.11 10.6 10.3 0.13 10.4 7.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.8 EGO54525.1 - 6.1 5.5 7.7 7.3 5.3 5.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Clr5 PF14420.1 EGO54527.1 - 2.3e-13 49.8 4.7 3.4e-13 49.2 3.3 1.3 1 0 0 1 1 1 1 Clr5 domain zf-Nse PF11789.3 EGO54528.1 - 3e-19 68.2 0.4 5e-19 67.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 EGO54528.1 - 0.00056 19.6 0.3 0.00088 19.0 0.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 EGO54528.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger AATF-Che1 PF13339.1 EGO54528.1 - 0.022 14.9 7.5 0.27 11.3 0.2 2.9 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor ADIP PF11559.3 EGO54528.1 - 0.024 14.5 3.6 0.045 13.6 1.7 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding zf-MIZ PF02891.15 EGO54528.1 - 0.033 13.6 1.0 0.068 12.6 0.7 1.5 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 EGO54528.1 - 0.047 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein GldM_N PF12081.3 EGO54528.1 - 0.079 12.4 1.1 0.14 11.6 0.7 1.5 1 1 0 1 1 1 0 GldM N-terminal domain zf-rbx1 PF12678.2 EGO54528.1 - 0.096 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger DUF1640 PF07798.6 EGO54528.1 - 0.11 12.4 1.0 0.19 11.7 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) zf-C3HC4_2 PF13923.1 EGO54528.1 - 0.14 12.1 0.6 0.24 11.4 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EGO54528.1 - 0.37 9.9 7.9 0.14 11.3 0.4 2.6 2 1 0 2 2 2 0 Rtf2 RING-finger IncA PF04156.9 EGO54528.1 - 0.59 9.7 2.9 0.66 9.5 1.4 1.5 1 1 1 2 2 2 0 IncA protein PAS_9 PF13426.1 EGO54529.1 - 1.1e-19 70.6 0.0 1.6e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EGO54529.1 - 0.0016 18.2 0.0 0.0057 16.4 0.0 1.8 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EGO54529.1 - 0.003 17.5 0.0 0.0062 16.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 EGO54529.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.6 EGO54529.1 - 0.099 12.7 0.1 1.6 8.8 0.1 2.3 1 1 0 1 1 1 0 PAS fold EF_assoc_2 PF08356.7 EGO54530.1 - 9.9e-36 121.3 0.0 2.1e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Miro PF08477.8 EGO54530.1 - 3.4e-35 121.1 0.0 3.9e-19 69.2 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 EGO54530.1 - 5.1e-33 112.1 1.5 6.1e-33 111.9 0.3 1.7 2 0 0 2 2 2 1 EF hand associated Ras PF00071.17 EGO54530.1 - 1.9e-25 89.1 0.0 3.6e-16 58.9 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EGO54530.1 - 4.6e-08 33.0 0.0 7.3e-05 22.6 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 EGO54530.1 - 2.2e-06 27.6 1.4 0.016 15.3 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair AAA_22 PF13401.1 EGO54530.1 - 7.8e-06 26.0 0.0 0.05 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGO54530.1 - 1.8e-05 24.1 0.0 0.039 13.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain EF-hand_1 PF00036.27 EGO54530.1 - 2.1e-05 23.5 5.0 0.071 12.4 0.4 2.7 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.1 EGO54530.1 - 4e-05 23.6 1.3 0.14 12.1 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain ABC_tran PF00005.22 EGO54530.1 - 4.1e-05 23.8 0.0 0.065 13.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 EGO54530.1 - 8.8e-05 21.7 0.0 0.16 11.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EGO54530.1 - 0.00029 20.3 0.0 0.5 9.7 0.0 3.1 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 EGO54530.1 - 0.00053 19.6 0.0 0.072 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EGO54530.1 - 0.00055 19.7 0.4 0.61 9.8 0.3 3.3 2 1 1 3 3 3 1 Dynamin family EF-hand_6 PF13405.1 EGO54530.1 - 0.0013 18.4 5.9 0.32 10.9 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain AAA_25 PF13481.1 EGO54530.1 - 0.0031 16.9 0.0 2 7.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EGO54530.1 - 0.0043 16.7 0.0 0.23 11.1 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EGO54530.1 - 0.0061 16.7 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 EGO54530.1 - 0.022 14.3 0.0 2.2 7.9 0.0 2.8 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.12 EGO54530.1 - 0.024 14.4 0.1 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF815 PF05673.8 EGO54530.1 - 0.029 13.3 0.1 1.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 EGO54530.1 - 0.03 14.2 0.1 11 5.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EGO54530.1 - 0.031 13.7 0.0 5.3 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 EGO54530.1 - 0.032 13.9 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 EGO54530.1 - 0.033 14.1 0.0 5.8 6.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EGO54530.1 - 0.039 14.2 0.7 5.3 7.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain IIGP PF05049.8 EGO54530.1 - 0.062 12.1 0.3 1.3 7.7 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Septin PF00735.13 EGO54530.1 - 0.062 12.3 0.0 0.92 8.4 0.0 2.1 2 0 0 2 2 2 0 Septin PRK PF00485.13 EGO54530.1 - 0.1 12.1 0.0 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.14 EGO54530.1 - 1.2 8.5 4.0 23 4.3 0.2 4.0 3 2 1 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain EF-hand_8 PF13833.1 EGO54530.1 - 2.2 7.9 5.4 6.8 6.3 0.4 2.6 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 EGO54530.1 - 3.4 7.1 7.7 0.99 8.8 1.3 2.6 2 0 0 2 2 2 0 EF hand WD40 PF00400.27 EGO54531.1 - 4.1e-21 74.0 17.4 3.5e-06 26.6 0.3 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EGO54531.1 - 4.5e-06 26.5 0.1 0.0067 16.1 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EGO54531.1 - 0.0031 15.4 0.0 0.0077 14.1 0.0 1.5 1 1 0 1 1 1 1 IKI3 family Cytochrom_D1 PF02239.11 EGO54531.1 - 0.059 11.6 0.0 0.12 10.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain Atx10homo_assoc PF09759.4 EGO54532.1 - 1e-09 38.0 0.0 2.9e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain PAT1 PF09770.4 EGO54532.1 - 3.8 5.6 18.9 6.8 4.7 13.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PNP_UDP_1 PF01048.15 EGO54533.1 - 1.7e-38 131.9 0.5 1.9e-38 131.7 0.4 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Aldolase_II PF00596.16 EGO54533.1 - 0.08 12.5 0.0 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 Class II Aldolase and Adducin N-terminal domain Med13_C PF06333.7 EGO54534.1 - 4.2e-119 397.8 10.6 4.2e-119 397.8 7.3 2.3 2 1 0 2 2 2 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 EGO54534.1 - 1.9e-65 221.1 0.0 1.9e-65 221.1 0.0 2.9 3 1 0 3 3 3 1 Mediator complex subunit 13 N-terminal NUC153 PF08159.7 EGO54535.1 - 2.7e-12 46.0 1.1 5.8e-12 44.9 0.8 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EGO54535.1 - 0.0059 16.4 0.0 8.4 6.4 0.0 3.9 3 1 0 3 3 3 1 WD domain, G-beta repeat CD99L2 PF12301.3 EGO54536.1 - 0.18 11.4 0.6 0.23 11.1 0.4 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 COQ7 PF03232.8 EGO54538.1 - 1.1e-67 226.7 0.0 1.3e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 ECM11 PF15463.1 EGO54538.1 - 0.69 10.1 2.3 5.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Extracellular mutant protein 11 Plus-3 PF03126.13 EGO54539.1 - 2.2e-32 111.3 0.1 7.8e-32 109.5 0.0 2.0 2 0 0 2 2 2 1 Plus-3 domain PLDc PF00614.17 EGO54540.1 - 8.1e-18 63.6 1.1 1.9e-09 37.0 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EGO54540.1 - 1.2e-12 47.6 0.1 2e-08 34.0 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EGO54540.1 - 6.3e-08 32.3 0.0 1.8e-06 27.6 0.0 2.8 2 1 0 2 2 2 1 PX domain Tubulin PF00091.20 EGO54541.1 - 2.6e-74 249.6 0.0 3.8e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGO54541.1 - 8.1e-47 158.3 0.4 1.7e-46 157.3 0.0 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EGO54541.1 - 1.6e-06 28.1 0.0 4.6e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Oxidored_q6 PF01058.17 EGO54542.1 - 2.8e-22 78.7 0.0 4.2e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Mpp10 PF04006.7 EGO54543.1 - 1.8e-91 307.4 92.7 4.1e-88 296.2 14.4 2.5 1 1 1 2 2 2 2 Mpp10 protein SSP160 PF06933.6 EGO54543.1 - 0.024 12.6 4.9 0.039 11.9 3.4 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SPX PF03105.14 EGO54544.1 - 5.9e-22 78.7 3.6 2.1e-14 54.0 0.0 3.3 2 2 1 3 3 3 2 SPX domain HAUS4 PF14735.1 EGO54544.1 - 0.033 13.4 0.7 0.064 12.5 0.2 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 3H PF02829.9 EGO54544.1 - 0.035 14.1 0.2 0.069 13.1 0.1 1.4 1 0 0 1 1 1 0 3H domain Exonuc_VII_L PF02601.10 EGO54544.1 - 0.11 11.6 0.9 0.18 10.9 0.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF837 PF05769.6 EGO54544.1 - 0.12 11.8 0.2 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF837) NMO PF03060.10 EGO54545.1 - 1.4e-44 152.6 10.6 9.7e-44 149.8 7.3 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 EGO54545.1 - 2.5e-08 33.1 6.3 4.1e-08 32.4 4.4 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EGO54545.1 - 1.8e-05 23.7 6.7 0.072 11.9 4.8 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EGO54545.1 - 0.0011 17.9 2.1 0.0016 17.4 1.5 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Amidohydro_3 PF07969.6 EGO54546.1 - 1.8e-52 178.9 0.6 5.8e-51 173.9 0.4 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EGO54546.1 - 0.011 15.4 0.7 0.03 13.9 0.0 2.0 2 0 0 2 2 2 0 Amidohydrolase family Amidohydro_5 PF13594.1 EGO54546.1 - 0.03 14.1 0.7 0.09 12.6 0.5 1.9 1 1 0 1 1 1 0 Amidohydrolase HECT PF00632.20 EGO54547.1 - 4.7e-93 311.8 0.0 7.5e-93 311.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EGO54547.1 - 3.5e-32 109.8 16.3 2.1e-11 43.4 1.4 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EGO54547.1 - 1.9e-17 62.8 0.2 4.3e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.17 EGO54548.1 - 5.2e-17 61.2 0.0 9.6e-17 60.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO54548.1 - 4e-15 55.5 0.0 6.7e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO54548.1 - 9.2e-05 22.2 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 EGO54548.1 - 0.03 12.1 5.2 0.039 11.8 3.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PLRV_ORF5 PF01690.12 EGO54548.1 - 0.7 8.9 9.1 0.78 8.8 6.3 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FimP PF09766.4 EGO54548.1 - 1.1 8.2 14.0 5.5 5.9 0.0 2.1 2 0 0 2 2 2 0 Fms-interacting protein VSG_B PF13206.1 EGO54548.1 - 1.2 8.2 5.9 1.5 7.8 4.1 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain DivIC PF04977.10 EGO54548.1 - 5.7 6.4 16.9 1.9 7.9 2.1 2.2 2 0 0 2 2 2 0 Septum formation initiator WD40 PF00400.27 EGO54550.1 - 1.2e-51 170.8 30.2 1.5e-08 34.2 0.7 11.7 11 0 0 11 11 11 11 WD domain, G-beta repeat Peptidase_S9_N PF02897.10 EGO54550.1 - 0.0082 14.7 0.1 0.021 13.3 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Cytochrom_D1 PF02239.11 EGO54550.1 - 0.024 12.9 0.0 2.6 6.2 0.0 2.8 2 2 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.7 EGO54550.1 - 0.048 13.3 0.2 61 3.4 0.0 4.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat MFS_1 PF07690.11 EGO54551.1 - 2.8e-41 141.3 45.0 7.5e-41 140.0 25.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGO54551.1 - 6.2e-05 21.3 5.3 6.2e-05 21.3 3.7 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pol_alpha_B_N PF08418.5 EGO54551.1 - 0.37 10.2 7.8 0.51 9.8 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal PAS PF00989.19 EGO54553.1 - 3e-05 23.7 0.0 6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 EGO54553.1 - 0.002 17.9 8.9 0.0047 16.8 6.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_4 PF08448.5 EGO54553.1 - 0.036 14.1 0.0 0.28 11.2 0.0 2.3 2 0 0 2 2 2 0 PAS fold PAS_8 PF13188.1 EGO54553.1 - 0.079 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 PAS domain PXA PF02194.10 EGO54554.1 - 4e-54 183.0 0.6 1.6e-53 181.0 0.0 2.4 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EGO54554.1 - 2.8e-31 107.9 0.0 7.8e-31 106.4 0.0 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 EGO54554.1 - 6.7e-21 74.2 0.6 1.9e-20 72.7 0.4 1.8 1 0 0 1 1 1 1 PX domain RGS PF00615.14 EGO54554.1 - 1e-09 38.4 0.0 3.4e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain Methyltransf_4 PF02390.12 EGO54555.1 - 4.2e-53 179.3 0.1 5.7e-53 178.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EGO54555.1 - 0.00013 21.9 0.1 0.00029 20.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO54555.1 - 0.0002 21.9 0.0 0.00039 20.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO54555.1 - 0.0025 17.4 0.0 0.0036 16.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO54555.1 - 0.0029 16.9 0.0 0.0061 15.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 EGO54555.1 - 0.0097 14.9 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_12 PF08242.7 EGO54555.1 - 0.011 16.1 0.0 0.034 14.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGO54555.1 - 0.02 15.3 0.0 0.2 12.1 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EGO54555.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EGO54555.1 - 0.076 13.3 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Homoserine_dh PF00742.14 EGO54556.1 - 2.2e-51 174.0 0.0 3.3e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EGO54556.1 - 2.3e-15 57.0 0.0 4.3e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.1 EGO54558.1 - 4e-31 106.9 13.9 4e-31 106.9 9.6 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) Caldesmon PF02029.10 EGO54558.1 - 3.1 6.1 35.3 0.37 9.1 5.2 2.1 2 0 0 2 2 2 0 Caldesmon Zn_clus PF00172.13 EGO54559.1 - 2.1e-08 33.9 7.7 3.5e-08 33.2 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGO54559.1 - 0.00051 18.7 0.9 0.0007 18.3 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.23 EGO54560.1 - 2.2e-80 270.1 0.1 2.8e-80 269.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MRP-S28 PF10213.4 EGO54563.1 - 6.5e-36 123.2 0.0 1.2e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Glyco_tran_28_C PF04101.11 EGO54564.1 - 2.2e-17 63.2 0.0 7.9e-17 61.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EGO54564.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Abhydrolase_6 PF12697.2 EGO54565.1 - 4.8e-27 95.3 0.1 7.1e-27 94.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO54565.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO54565.1 - 8.2e-05 22.2 0.0 0.00069 19.2 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO54565.1 - 0.077 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ndr PF03096.9 EGO54565.1 - 0.21 10.0 0.0 0.33 9.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family PTCB-BRCT PF12738.2 EGO54566.1 - 5.1e-33 112.7 1.9 6.7e-21 73.9 0.1 4.2 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 EGO54566.1 - 1.2e-22 79.8 0.0 1.7e-08 34.4 0.0 5.1 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain Mitofilin PF09731.4 EGO54566.1 - 9.1 4.7 9.6 17 3.9 6.7 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HMG_CoA_synt_C PF08540.5 EGO54567.1 - 1.5e-99 333.0 0.1 1.9e-99 332.7 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EGO54567.1 - 5.7e-95 315.7 0.2 8.5e-95 315.2 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal BCS1_N PF08740.6 EGO54568.1 - 4.8e-58 195.8 0.6 4.8e-58 195.8 0.4 2.5 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 EGO54568.1 - 1.6e-16 60.7 0.0 3.2e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGO54568.1 - 0.0012 18.2 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGO54568.1 - 0.0014 17.7 0.0 0.0026 16.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGO54568.1 - 0.0023 17.9 0.6 0.014 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EGO54568.1 - 0.003 17.2 0.2 0.058 13.1 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain AAA_5 PF07728.9 EGO54568.1 - 0.004 16.8 0.0 0.032 13.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EGO54568.1 - 0.0063 17.3 1.6 0.022 15.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain RP-C_C PF11800.3 EGO54568.1 - 0.0075 15.9 2.5 0.0075 15.9 1.7 2.3 1 1 1 2 2 1 1 Replication protein C C-terminal region Macoilin PF09726.4 EGO54568.1 - 0.19 9.9 22.9 0.28 9.4 15.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Cwf_Cwc_15 PF04889.7 EGO54568.1 - 0.26 10.9 30.6 0.6 9.7 21.2 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MIP-T3 PF10243.4 EGO54568.1 - 0.77 8.1 37.7 1.1 7.6 26.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF572 PF04502.8 EGO54568.1 - 1.6 7.8 29.5 3 6.9 20.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pol_alpha_B_N PF08418.5 EGO54568.1 - 2 7.8 24.1 4.1 6.8 16.7 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF1675 PF07897.6 EGO54568.1 - 3 7.6 23.9 5.1 6.8 16.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Na_trans_assoc PF06512.8 EGO54568.1 - 3.6 7.5 24.3 6.7 6.6 16.8 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated SAPS PF04499.10 EGO54568.1 - 9.6 4.7 14.0 15 4.0 9.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BAF1_ABF1 PF04684.8 EGO54571.1 - 9.1 4.9 7.0 13 4.5 4.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Cellulase PF00150.13 EGO54574.1 - 7.3e-12 45.0 0.2 7.3e-12 45.0 0.1 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF1510 PF07423.6 EGO54574.1 - 0.022 14.1 0.0 0.022 14.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Protocadherin PF08374.6 EGO54574.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Protocadherin Shisa PF13908.1 EGO54574.1 - 0.27 11.3 1.7 3.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Synaptobrevin PF00957.16 EGO54574.1 - 7.1 6.3 6.4 12 5.5 4.4 1.3 1 0 0 1 1 1 0 Synaptobrevin Transket_pyr PF02779.19 EGO54575.1 - 5.2e-42 143.3 0.0 8.9e-42 142.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGO54575.1 - 4.3e-32 110.6 0.1 9.3e-32 109.5 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain F-actin_cap_A PF01267.12 EGO54576.1 - 4.6e-92 307.9 0.1 5.2e-92 307.7 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Cyt-b5 PF00173.23 EGO54577.1 - 4.3e-26 90.5 0.1 5.3e-26 90.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Tricorn_C1 PF14684.1 EGO54578.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease C1 domain NAD_binding_10 PF13460.1 EGO54579.1 - 1.1e-09 38.5 0.5 1.4e-09 38.1 0.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO54579.1 - 4.8e-08 32.7 0.0 8.8e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.5 EGO54579.1 - 6.8e-08 31.3 0.0 1.4e-07 30.3 0.0 1.4 2 0 0 2 2 2 1 HIM1 NmrA PF05368.8 EGO54579.1 - 6.3e-05 22.3 0.0 0.00022 20.5 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EGO54579.1 - 6.5e-05 21.9 0.0 0.17 10.7 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EGO54579.1 - 0.019 13.6 0.0 0.21 10.2 0.0 2.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EGO54579.1 - 0.048 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain WGG PF10273.4 EGO54580.1 - 1.7e-37 127.3 0.6 2.7e-37 126.7 0.4 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Mob1_phocein PF03637.12 EGO54580.1 - 0.057 13.0 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Mob1/phocein family RRP7 PF12923.2 EGO54580.1 - 0.24 11.3 0.2 0.24 11.3 0.1 2.3 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) FAM176 PF14851.1 EGO54580.1 - 2.2 7.9 7.5 9.9 5.8 0.3 2.2 2 0 0 2 2 2 0 FAM176 family BSD PF03909.12 EGO54581.1 - 1.4e-16 60.0 0.1 2.8e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 BSD domain Phage_Mu_F PF04233.9 EGO54581.1 - 0.023 15.2 0.1 0.087 13.3 0.1 1.9 1 0 0 1 1 1 0 Phage Mu protein F like protein EzrA PF06160.7 EGO54581.1 - 0.024 12.8 2.2 0.21 9.7 0.0 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA TPR_2 PF07719.12 EGO54581.1 - 0.12 12.3 0.9 0.44 10.5 0.6 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat ATG16 PF08614.6 EGO54581.1 - 2.3 7.9 12.0 0.38 10.5 4.0 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) PAP1 PF08601.5 EGO54582.1 - 3.5e-88 296.6 2.2 3.5e-88 296.6 1.5 2.3 2 1 0 2 2 1 1 Transcription factor PAP1 bZIP_1 PF00170.16 EGO54582.1 - 1.6e-07 31.1 14.9 1.6e-07 31.1 10.3 1.8 2 0 0 2 2 2 1 bZIP transcription factor Adeno_PIX PF03955.9 EGO54582.1 - 0.0048 17.4 2.8 0.0063 17.0 0.4 2.2 2 0 0 2 2 2 1 Adenovirus hexon-associated protein (IX) GAS PF13851.1 EGO54582.1 - 0.0053 15.9 8.3 0.0095 15.1 5.8 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Ssl1 PF04056.9 EGO54582.1 - 0.011 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Ssl1-like Glutaredoxin2_C PF04399.8 EGO54582.1 - 0.043 13.3 2.3 0.87 9.1 1.6 2.4 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain dsrm PF00035.20 EGO54582.1 - 0.069 13.7 0.1 0.18 12.4 0.1 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif DUF904 PF06005.7 EGO54582.1 - 0.076 13.3 7.3 0.15 12.3 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Cluap1 PF10234.4 EGO54582.1 - 0.22 10.6 7.0 0.38 9.9 4.8 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 bZIP_2 PF07716.10 EGO54582.1 - 0.4 10.5 16.0 0.78 9.6 10.4 1.9 1 1 0 1 1 1 0 Basic region leucine zipper IncA PF04156.9 EGO54582.1 - 0.48 9.9 3.7 0.98 8.9 2.6 1.4 1 0 0 1 1 1 0 IncA protein bZIP_Maf PF03131.12 EGO54582.1 - 1 9.6 11.9 0.59 10.4 6.3 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Bap31 PF05529.7 EGO54582.1 - 5.4 6.4 7.4 9.7 5.5 5.2 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like CENP-R PF06729.7 EGO54583.1 - 0.059 13.0 1.2 0.058 13.0 0.8 1.2 1 0 0 1 1 1 0 Kinetochore component, CENP-R PRP1_N PF06424.7 EGO54583.1 - 0.067 13.5 1.3 0.082 13.2 0.9 1.0 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Abhydrolase_3 PF07859.8 EGO54584.1 - 9.3e-48 162.5 0.3 2.4e-47 161.2 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO54584.1 - 7.1e-05 22.5 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EGO54584.1 - 0.00034 19.3 0.1 0.0069 15.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Pex14_N PF04695.8 EGO54586.1 - 4.4e-33 114.2 7.5 1.8e-32 112.2 0.0 2.8 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 EGO54586.1 - 0.00026 20.6 4.7 0.0004 20.0 2.0 2.0 2 0 0 2 2 2 1 IncA protein zf-C4H2 PF10146.4 EGO54586.1 - 0.00037 20.5 3.4 0.00037 20.5 2.3 2.0 2 0 0 2 2 2 1 Zinc finger-containing protein CR6_interact PF10147.4 EGO54586.1 - 0.00047 19.5 0.2 0.00072 18.9 0.1 1.3 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 BicD PF09730.4 EGO54586.1 - 0.0015 16.9 6.3 0.0023 16.3 4.4 1.2 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D DUF3584 PF12128.3 EGO54586.1 - 0.028 11.7 11.2 0.041 11.2 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PhaP_Bmeg PF09602.5 EGO54586.1 - 0.033 14.0 4.0 0.065 13.0 2.8 1.5 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF1978 PF09321.5 EGO54586.1 - 0.037 13.4 7.5 0.064 12.6 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) HSA PF07529.8 EGO54586.1 - 0.049 13.4 0.3 0.1 12.4 0.2 1.4 1 0 0 1 1 1 0 HSA DUF4211 PF13926.1 EGO54586.1 - 0.079 12.3 1.1 0.12 11.8 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) DUF848 PF05852.6 EGO54586.1 - 0.14 12.0 9.2 0.29 10.9 6.4 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Myosin_tail_1 PF01576.14 EGO54586.1 - 0.14 9.8 16.2 0.2 9.3 11.3 1.1 1 0 0 1 1 1 0 Myosin tail tRNA-synt_His PF13393.1 EGO54586.1 - 0.54 9.2 3.6 2.9 6.8 0.0 2.2 1 1 1 2 2 2 0 Histidyl-tRNA synthetase DUF1759 PF03564.10 EGO54586.1 - 0.57 9.9 4.1 0.2 11.4 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Prominin PF05478.6 EGO54586.1 - 0.65 7.4 2.5 0.95 6.9 1.8 1.2 1 0 0 1 1 1 0 Prominin FUSC PF04632.7 EGO54586.1 - 0.67 8.3 2.2 1 7.7 1.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Baculo_PEP_C PF04513.7 EGO54586.1 - 0.72 9.6 9.9 0.92 9.3 1.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.6 EGO54586.1 - 0.72 10.2 8.3 1.8 9.0 3.2 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HLH PF00010.21 EGO54586.1 - 0.73 9.5 8.6 12 5.6 0.3 3.2 1 1 1 2 2 2 0 Helix-loop-helix DNA-binding domain EAP30 PF04157.11 EGO54586.1 - 0.74 8.9 4.7 1.3 8.1 3.1 1.5 1 1 0 1 1 1 0 EAP30/Vps36 family ERM PF00769.14 EGO54586.1 - 0.94 8.9 15.5 2.2 7.7 10.8 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Orbi_VP5 PF00901.12 EGO54586.1 - 1.2 7.2 4.6 0.93 7.6 1.4 1.8 1 1 1 2 2 2 0 Orbivirus outer capsid protein VP5 Spectrin PF00435.16 EGO54586.1 - 2.4 8.5 9.5 6.3 7.1 5.6 2.2 1 1 0 1 1 1 0 Spectrin repeat Syntaxin PF00804.20 EGO54586.1 - 4 7.6 11.7 18 5.5 8.1 2.1 1 1 0 1 1 1 0 Syntaxin AAA_13 PF13166.1 EGO54586.1 - 4.1 5.7 9.6 8 4.7 6.6 1.5 1 1 0 1 1 1 0 AAA domain DUF1451 PF07295.6 EGO54586.1 - 4.3 7.0 8.4 7.9 6.2 5.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Ndc80_HEC PF03801.8 EGO54587.1 - 1.4e-61 206.5 0.0 2.7e-61 205.6 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family WASH_WAHD PF11945.3 EGO54587.1 - 0.0077 15.5 3.7 0.0077 15.5 2.5 1.9 2 0 0 2 2 2 1 WAHD domain of WASH complex DUF1664 PF07889.7 EGO54587.1 - 0.0096 15.7 1.1 0.0096 15.7 0.8 4.1 2 2 2 4 4 4 1 Protein of unknown function (DUF1664) Anth_Ig PF05587.8 EGO54587.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Anthrax receptor extracellular domain FliJ PF02050.11 EGO54587.1 - 0.16 11.9 35.3 0.38 10.8 5.9 3.8 2 2 1 3 3 3 0 Flagellar FliJ protein Filament PF00038.16 EGO54587.1 - 0.54 9.6 51.5 1.5 8.2 13.9 3.3 2 1 0 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 EGO54587.1 - 0.69 9.6 42.0 0.14 11.8 11.3 3.5 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.3 EGO54587.1 - 0.7 7.1 36.7 0.26 8.5 7.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 EGO54587.1 - 1 8.4 4.5 0.37 9.9 0.3 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 EGO54587.1 - 4.2 5.0 29.2 0.82 7.4 6.0 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 EGO54587.1 - 4.5 7.1 57.4 1 9.2 12.5 4.3 2 2 2 4 4 4 0 Tropomyosin like ESCRT-II PF05871.7 EGO54588.1 - 1.4e-47 161.0 0.0 1.8e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit KH_1 PF00013.24 EGO54589.1 - 6.4e-95 310.7 34.3 6.5e-14 51.3 0.1 11.8 11 1 0 11 11 11 10 KH domain KH_3 PF13014.1 EGO54589.1 - 1.3e-66 219.3 26.0 6e-10 38.5 0.0 11.9 12 0 0 12 12 12 9 KH domain KH_2 PF07650.12 EGO54589.1 - 6e-10 38.5 26.5 0.0066 15.9 0.1 7.8 7 1 0 8 8 8 4 KH domain SLS PF14611.1 EGO54589.1 - 6.4e-07 29.0 10.5 0.031 13.7 0.0 7.2 4 2 3 8 8 8 2 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 EGO54589.1 - 8.3e-06 25.3 6.4 0.041 13.5 0.2 5.2 4 0 0 4 4 4 2 KH domain DUF2096 PF09869.4 EGO54589.1 - 0.04 13.7 0.3 10 5.9 0.0 3.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) Bunya_NS-S PF01104.12 EGO54590.1 - 0.31 10.5 3.0 0.6 9.6 2.1 1.5 1 1 0 1 1 1 0 Bunyavirus non-structural protein NS-s KASH PF10541.4 EGO54592.1 - 0.31 10.9 6.2 0.67 9.8 4.3 1.6 1 0 0 1 1 1 0 Nuclear envelope localisation domain Pkinase PF00069.20 EGO54593.1 - 2.1e-71 240.1 0.0 3.2e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO54593.1 - 1.6e-45 155.1 0.0 2.8e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EGO54593.1 - 2.7e-16 59.6 0.0 2.7e-16 59.6 0.0 3.1 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 EGO54593.1 - 5.4e-08 32.1 0.0 9.4e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO54593.1 - 0.022 14.5 4.3 0.12 12.1 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EGO54593.1 - 0.097 11.7 0.1 0.43 9.5 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.7 EGO54593.1 - 0.14 11.4 0.0 0.41 9.8 0.0 1.7 2 0 0 2 2 2 0 DSHCT (NUC185) domain adh_short PF00106.20 EGO54594.1 - 4.7e-30 104.7 0.9 7.4e-30 104.0 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO54594.1 - 3.9e-28 98.8 0.2 5.4e-28 98.3 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO54594.1 - 1e-11 44.8 0.2 1.6e-11 44.2 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO54594.1 - 8.4e-06 25.3 0.1 4.1e-05 23.1 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.17 EGO54594.1 - 0.00057 19.5 0.6 0.0022 17.6 0.1 2.2 2 0 0 2 2 2 1 PA domain 3Beta_HSD PF01073.14 EGO54594.1 - 0.026 13.2 0.0 0.044 12.4 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EGO54594.1 - 0.028 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Arginase PF00491.16 EGO54594.1 - 0.041 13.1 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Arginase family ARID PF01388.16 EGO54595.1 - 3.2e-19 68.5 0.0 6.3e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain SelR PF01641.13 EGO54597.1 - 4e-49 165.4 0.1 4.8e-49 165.1 0.1 1.0 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 EGO54597.1 - 0.03 14.0 0.5 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) DZR PF12773.2 EGO54597.1 - 0.034 13.9 3.6 1.4 8.8 2.9 2.3 1 1 1 2 2 2 0 Double zinc ribbon Yippee-Mis18 PF03226.9 EGO54597.1 - 0.05 13.6 0.6 0.16 12.0 0.4 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cytochrome_C554 PF13435.1 EGO54597.1 - 0.083 12.9 0.5 0.14 12.1 0.3 1.5 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Zn_Tnp_IS1595 PF12760.2 EGO54597.1 - 0.26 11.1 1.5 14 5.5 0.0 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EGO54597.1 - 0.37 10.1 0.2 0.37 10.1 0.1 2.4 3 0 0 3 3 3 0 TFIIB zinc-binding SpdB PF05122.8 EGO54597.1 - 0.58 10.2 3.4 16 5.6 0.2 2.4 1 1 1 2 2 2 0 Mobile element transfer protein DNA_RNApol_7kD PF03604.8 EGO54597.1 - 1.5 8.3 3.5 13 5.3 0.3 2.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit ArfGap PF01412.13 EGO54598.1 - 6.6e-41 138.7 1.1 1e-40 138.1 0.7 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Synaptobrevin PF00957.16 EGO54599.1 - 0.0043 16.6 0.2 0.36 10.4 0.0 2.0 1 1 1 2 2 2 2 Synaptobrevin DUF500 PF04366.7 EGO54600.1 - 2.4e-44 149.8 0.2 4.3e-44 148.9 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EGO54600.1 - 9.4e-13 47.3 0.2 2.5e-12 45.9 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EGO54600.1 - 8.4e-12 44.4 0.0 1.5e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGO54600.1 - 1.1e-10 40.8 0.0 2e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Arrestin_C PF02752.17 EGO54601.1 - 2e-18 66.8 0.0 7.4e-18 64.9 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EGO54601.1 - 1.7e-13 50.6 0.0 6.8e-13 48.6 0.0 2.1 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EGO54601.1 - 0.0016 17.9 0.0 0.0041 16.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like PH PF00169.24 EGO54602.1 - 0.00059 20.0 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 PH domain CK2S PF15011.1 EGO54602.1 - 0.012 15.3 1.3 1.9 8.2 0.0 3.0 2 1 0 3 3 3 0 Casein Kinase 2 substrate DUF1043 PF06295.7 EGO54602.1 - 0.035 13.7 0.1 0.035 13.7 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) Laminin_I PF06008.9 EGO54602.1 - 0.085 12.1 9.3 0.012 14.9 2.2 2.1 2 0 0 2 2 2 0 Laminin Domain I Alba PF01918.16 EGO54604.1 - 1e-09 37.8 0.0 1.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Alba DUF202 PF02656.10 EGO54605.1 - 1.6e-13 50.6 3.3 1.6e-13 50.6 2.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2189 PF09955.4 EGO54605.1 - 0.64 9.9 7.1 0.13 12.2 1.6 1.8 1 1 2 3 3 3 0 Predicted integral membrane protein (DUF2189) Tctex-1 PF03645.8 EGO54606.1 - 4.2e-35 119.6 0.0 5.3e-35 119.3 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family F-box-like PF12937.2 EGO54607.1 - 0.0013 18.4 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO54607.1 - 0.0092 15.6 0.0 0.024 14.3 0.0 1.7 2 0 0 2 2 2 1 F-box domain CTP_transf_2 PF01467.21 EGO54608.1 - 3.4e-22 79.1 0.0 7e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase Fungal_trans PF04082.13 EGO54609.1 - 2.4e-10 39.7 0.1 8.6e-10 37.9 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain FTHFS PF01268.14 EGO54610.1 - 4.1e-260 863.5 0.5 5.3e-260 863.1 0.0 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EGO54610.1 - 1.3e-68 229.1 0.5 1.3e-68 229.1 0.3 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EGO54610.1 - 1.6e-38 131.3 0.2 3.3e-38 130.3 0.2 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.22 EGO54610.1 - 0.079 12.3 1.3 0.73 9.2 0.0 2.4 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain WD40 PF00400.27 EGO54611.1 - 1.2e-31 107.4 2.5 3.9e-11 42.3 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGO54611.1 - 0.00066 18.5 0.0 0.006 15.3 0.0 2.1 1 1 0 1 1 1 1 Nup133 N terminal like Coatomer_WDAD PF04053.9 EGO54611.1 - 0.0017 17.2 0.0 0.3 9.8 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region Nup160 PF11715.3 EGO54611.1 - 0.013 13.7 0.0 0.018 13.2 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Gmad1 PF10647.4 EGO54611.1 - 0.014 14.7 0.3 0.11 11.9 0.2 2.0 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain SdiA-regulated PF06977.6 EGO54611.1 - 0.12 11.2 0.0 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 SdiA-regulated SNF2_N PF00176.18 EGO54612.1 - 3.6e-83 278.7 0.2 5.8e-83 278.1 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EGO54612.1 - 3.6e-46 155.7 4.1 1e-45 154.2 2.8 1.9 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 EGO54612.1 - 3.1e-37 127.4 3.2 3.1e-37 127.4 2.2 3.3 2 0 0 2 2 2 1 HAND Helicase_C PF00271.26 EGO54612.1 - 1.2e-15 57.1 0.0 5.4e-15 55.0 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO54612.1 - 5.3e-10 39.4 0.1 3.7e-09 36.6 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGO54612.1 - 1.8e-06 27.5 0.0 4.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 EGO54612.1 - 0.026 13.9 0.1 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 EGO54612.1 - 0.041 13.7 0.1 0.15 11.9 0.1 2.0 1 0 0 1 1 1 0 AAA domain DUF4588 PF15251.1 EGO54613.1 - 0.00012 22.1 9.3 0.00019 21.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4588) Suf PF05843.9 EGO54613.1 - 0.18 11.4 3.4 0.32 10.6 2.3 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Mcm10 PF09332.6 EGO54613.1 - 0.22 10.8 2.4 0.32 10.2 0.0 2.0 2 0 0 2 2 2 0 Mcm10 replication factor zf-RING_2 PF13639.1 EGO54619.1 - 3.6e-07 29.8 6.3 6.5e-07 29.0 4.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO54619.1 - 4.3e-07 29.8 8.0 8e-07 28.9 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO54619.1 - 4.5e-07 29.4 7.0 8.4e-07 28.5 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO54619.1 - 1.1e-06 28.2 5.7 1.8e-06 27.4 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO54619.1 - 5.4e-06 26.0 5.1 9.8e-06 25.2 3.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGO54619.1 - 0.00013 21.7 3.2 0.00013 21.7 2.2 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGO54619.1 - 0.008 15.8 6.4 0.02 14.6 4.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger TerY-C PF15616.1 EGO54619.1 - 0.068 13.1 1.4 0.16 11.9 0.2 2.0 2 0 0 2 2 2 0 TerY-C metal binding domain Prominin PF05478.6 EGO54620.1 - 0.18 9.3 0.1 0.27 8.7 0.1 1.2 1 0 0 1 1 1 0 Prominin NAD_binding_6 PF08030.7 EGO54621.1 - 2.5e-20 72.9 0.0 4.8e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGO54621.1 - 2.2e-12 46.7 0.0 4.4e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGO54621.1 - 0.00044 20.3 2.5 0.00091 19.3 1.8 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EGO54621.1 - 0.00068 20.1 0.0 0.042 14.4 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain RTA1 PF04479.8 EGO54624.1 - 9e-12 44.9 9.9 1.7e-11 44.0 6.9 1.3 1 1 0 1 1 1 1 RTA1 like protein PGAP1 PF07819.8 EGO54625.1 - 7.5e-09 35.4 0.1 1.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EGO54625.1 - 4.4e-08 33.2 0.0 9.2e-08 32.2 0.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 EGO54625.1 - 5.4e-06 25.8 0.0 1.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 EGO54625.1 - 0.00011 21.8 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO54625.1 - 0.00014 21.6 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EGO54625.1 - 0.00014 20.9 0.0 0.00024 20.2 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Thioesterase PF00975.15 EGO54625.1 - 0.0028 17.9 0.0 0.0038 17.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF900 PF05990.7 EGO54625.1 - 0.0073 15.6 0.0 0.01 15.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.8 EGO54625.1 - 0.0095 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase DUF915 PF06028.6 EGO54625.1 - 0.012 14.7 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.13 EGO54625.1 - 0.012 14.9 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 2) DUF1793 PF08760.6 EGO54627.1 - 8.8e-54 181.9 0.5 1.8e-53 180.9 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) UPF0160 PF03690.8 EGO54628.1 - 2.4e-124 414.9 0.0 2.7e-124 414.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ino80_Iec3 PF14612.1 EGO54629.1 - 8.2e-64 215.8 4.9 7.1e-34 117.8 1.7 2.1 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling HTH_28 PF13518.1 EGO54629.1 - 0.015 15.2 0.4 6.8 6.8 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain DUF908 PF06012.7 EGO54629.1 - 0.052 12.8 0.2 0.081 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Iso_dh PF00180.15 EGO54630.1 - 3.2e-70 236.8 0.0 3.7e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3364 PF11844.3 EGO54630.1 - 3.9 7.5 5.4 3.7 7.6 0.1 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF3364) Not3 PF04065.10 EGO54632.1 - 3.1e-99 330.9 20.4 4.6e-99 330.4 14.1 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EGO54632.1 - 1.5e-42 144.6 12.7 4e-42 143.2 8.8 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF1192 PF06698.6 EGO54632.1 - 0.0021 17.8 3.5 0.0026 17.5 0.7 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) DUF2373 PF10180.4 EGO54632.1 - 0.0075 15.7 3.2 0.016 14.7 2.2 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Syntaxin PF00804.20 EGO54632.1 - 0.0087 16.2 12.5 0.02 15.0 3.7 2.6 2 0 0 2 2 2 1 Syntaxin Cep57_MT_bd PF06657.8 EGO54632.1 - 0.0095 15.8 5.7 0.04 13.8 0.5 2.9 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Snapin_Pallidin PF14712.1 EGO54632.1 - 0.041 14.1 6.0 0.49 10.7 0.1 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Med10 PF09748.4 EGO54632.1 - 0.2 11.5 3.2 0.37 10.6 1.7 1.9 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex Poty_PP PF08440.5 EGO54632.1 - 0.23 10.4 3.2 0.13 11.3 0.7 1.6 2 0 0 2 2 2 0 Potyviridae polyprotein Syntaxin_2 PF14523.1 EGO54632.1 - 0.46 10.5 6.8 0.27 11.3 2.0 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Sec5 PF15469.1 EGO54632.1 - 0.47 10.1 7.9 1 9.0 0.8 2.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 CorA PF01544.13 EGO54632.1 - 2.5 7.0 4.7 0.89 8.5 0.5 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF241 PF03087.9 EGO54632.1 - 3.4 7.0 10.1 2.9 7.3 5.8 1.6 1 1 0 1 1 1 0 Arabidopsis protein of unknown function Tyr_Deacylase PF02580.11 EGO54633.1 - 1.2e-36 125.8 0.0 1.8e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DMRL_synthase PF00885.14 EGO54633.1 - 0.08 12.6 1.6 0.44 10.1 0.1 2.2 2 1 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase Pro_isomerase PF00160.16 EGO54634.1 - 1.9e-47 161.3 0.3 3e-47 160.7 0.2 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EGO54634.1 - 1e-09 37.9 7.7 2.1e-06 27.2 0.2 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGO54634.1 - 1.1e-06 28.0 2.5 0.0022 17.8 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGO54634.1 - 3.4e-06 26.4 1.1 0.0056 16.2 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO54634.1 - 7.7e-05 22.5 0.7 0.0012 18.6 0.4 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO54634.1 - 0.0085 15.8 1.0 0.022 14.4 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGO54634.1 - 0.021 15.4 1.0 0.19 12.4 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGO54634.1 - 0.027 14.8 0.7 0.11 12.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGO54634.1 - 0.038 14.6 1.3 0.22 12.2 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RasGAP PF00616.14 EGO54635.1 - 6.8e-45 153.1 0.0 1.5e-44 151.9 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EGO54635.1 - 0.00093 19.0 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain 2_5_RNA_ligase2 PF13563.1 EGO54636.1 - 0.0061 16.2 1.4 0.081 12.6 1.0 2.1 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily Ureidogly_hydro PF04115.7 EGO54637.1 - 9.7e-37 125.8 0.0 1.1e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase MFS_1 PF07690.11 EGO54638.1 - 0.035 12.8 10.2 0.0092 14.7 1.7 2.7 2 1 0 2 2 2 0 Major Facilitator Superfamily bZIP_1 PF00170.16 EGO54640.1 - 0.65 9.9 18.2 0.2 11.6 6.3 2.1 1 1 1 2 2 2 0 bZIP transcription factor Mnd1 PF03962.10 EGO54640.1 - 0.76 9.4 5.2 1 8.9 3.6 1.1 1 0 0 1 1 1 0 Mnd1 family PseudoU_synth_2 PF00849.17 EGO54641.1 - 1.9e-31 109.1 0.0 2.7e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ub-Mut7C PF14451.1 EGO54641.1 - 0.0025 17.2 0.1 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 Mut7-C ubiquitin TGS PF02824.16 EGO54641.1 - 0.038 13.8 0.2 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 TGS domain S4 PF01479.20 EGO54641.1 - 0.11 11.9 0.9 0.31 10.5 0.1 2.1 2 0 0 2 2 2 0 S4 domain DUF3535 PF12054.3 EGO54646.1 - 0.11 11.1 0.1 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) EMP70 PF02990.11 EGO54647.1 - 0.077 11.4 2.6 0.084 11.3 1.8 1.0 1 0 0 1 1 1 0 Endomembrane protein 70 GnHR_trans PF12369.3 EGO54649.1 - 0.07 13.5 0.0 0.071 13.5 0.0 1.1 1 0 0 1 1 1 0 Gonadotropin hormone receptor transmembrane region DUF3368 PF11848.3 EGO54651.1 - 0.078 12.5 0.1 0.13 11.8 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3368) ketoacyl-synt PF00109.21 EGO54652.1 - 5.7e-75 252.0 0.0 1.3e-74 250.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGO54652.1 - 9.7e-61 205.8 0.0 1.5e-60 205.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EGO54652.1 - 1.3e-54 184.6 1.5 3.3e-54 183.3 0.3 2.4 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EGO54652.1 - 1.4e-43 148.7 0.4 1.4e-43 148.7 0.3 3.0 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EGO54652.1 - 1.8e-39 134.2 0.1 7.8e-39 132.2 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EGO54652.1 - 1e-38 133.2 0.0 2.7e-38 131.8 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 EGO54652.1 - 6.3e-16 58.1 0.1 2.1e-15 56.3 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO54652.1 - 3.1e-10 41.0 0.1 1.7e-09 38.6 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO54652.1 - 1.2e-06 28.1 0.0 3.1e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EGO54652.1 - 0.00061 18.8 0.1 0.0012 17.8 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EGO54652.1 - 0.0014 18.8 1.6 0.0037 17.5 0.6 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Shikimate_DH PF01488.15 EGO54652.1 - 0.0044 17.1 0.1 0.013 15.5 0.1 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 EGO54652.1 - 0.013 15.2 0.0 0.055 13.2 0.0 1.9 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase FSH1 PF03959.8 EGO54654.1 - 5.2e-31 107.7 0.0 9.7e-31 106.8 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PE-PPE PF08237.6 EGO54654.1 - 0.049 13.0 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_2 PF02230.11 EGO54654.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase ABC_membrane PF00664.18 EGO54655.1 - 8e-48 163.2 20.0 1.6e-35 122.9 4.2 3.1 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGO54655.1 - 5.1e-44 149.8 0.0 4.4e-31 107.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGO54655.1 - 1.1e-13 50.9 0.9 1.6e-05 24.2 0.1 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGO54655.1 - 9.2e-10 38.9 0.0 0.0094 15.9 0.0 3.5 3 1 1 4 4 3 2 AAA domain SbcCD_C PF13558.1 EGO54655.1 - 1.3e-06 28.2 0.4 0.0048 16.7 0.1 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EGO54655.1 - 2e-05 24.7 0.1 0.008 16.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGO54655.1 - 0.00015 21.7 0.0 0.00041 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EGO54655.1 - 0.00027 21.7 0.0 0.00058 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 EGO54655.1 - 0.00061 18.4 0.1 0.0042 15.7 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA PF00004.24 EGO54655.1 - 0.0012 19.0 0.2 1.4 9.1 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EGO54655.1 - 0.0041 16.7 0.2 0.069 12.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain MoaE PF02391.12 EGO54655.1 - 0.0096 15.7 0.2 0.33 10.7 0.0 2.3 2 0 0 2 2 2 1 MoaE protein Rad17 PF03215.10 EGO54655.1 - 0.011 14.5 0.0 0.02 13.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EGO54655.1 - 0.028 14.3 0.0 0.34 10.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EGO54655.1 - 0.046 13.1 0.3 5.4 6.3 0.0 3.2 3 0 0 3 3 3 0 AAA-like domain AAA_5 PF07728.9 EGO54655.1 - 0.048 13.3 0.0 0.38 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EGO54655.1 - 0.059 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGO54655.1 - 0.079 12.1 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Glyco_hydro_71 PF03659.9 EGO54656.1 - 1.7e-143 477.7 4.7 2e-143 477.5 3.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 EGO54656.1 - 0.044 13.5 0.0 0.1 12.2 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Aldo_ket_red PF00248.16 EGO54657.1 - 4.6e-71 238.9 0.0 5.7e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family vMSA PF00695.14 EGO54658.1 - 0.73 8.9 3.5 1 8.4 2.4 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Band_3_cyto PF07565.8 EGO54658.1 - 7.1 6.0 10.6 17 4.8 6.5 1.8 1 1 1 2 2 2 0 Band 3 cytoplasmic domain Cupin_2 PF07883.6 EGO54659.1 - 1.4e-14 53.2 0.0 2e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EGO54659.1 - 2.6e-08 33.6 0.0 3.5e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EGO54659.1 - 1.2e-06 27.9 0.0 1.5e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EGO54659.1 - 8.8e-05 22.1 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EGO54659.1 - 0.00012 21.3 0.0 0.00023 20.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 EGO54659.1 - 0.0064 16.1 0.0 0.0082 15.7 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase CENP-C_C PF11699.3 EGO54659.1 - 0.0065 16.4 0.0 0.009 15.9 0.0 1.2 1 0 0 1 1 1 1 Mif2/CENP-C like ARD PF03079.9 EGO54659.1 - 0.0096 15.8 0.1 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 ARD/ARD' family EutQ PF06249.7 EGO54659.1 - 0.029 13.9 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ DUF1498 PF07385.7 EGO54659.1 - 0.12 11.5 0.0 0.41 9.7 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1498) Pkinase PF00069.20 EGO54660.1 - 8.3e-28 97.2 0.0 1.4e-27 96.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO54660.1 - 4e-15 55.5 0.0 2.8e-14 52.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase FGGY_C PF02782.11 EGO54662.1 - 1.8e-71 239.8 0.9 3.6e-71 238.9 0.6 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGO54662.1 - 3.9e-47 160.6 0.0 6.5e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain NTP_transferase PF00483.18 EGO54663.1 - 1.3e-49 168.7 0.0 3.3e-49 167.4 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EGO54663.1 - 2.4e-16 58.3 12.7 1.8e-09 36.7 1.3 3.9 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EGO54663.1 - 1.1e-10 41.8 0.0 1.6e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EGO54663.1 - 5.4e-08 32.2 5.3 7.9e-07 28.5 0.7 3.0 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DND1_DSRM PF14709.1 EGO54665.1 - 0.00013 22.1 0.1 0.00037 20.7 0.0 1.8 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 EGO54665.1 - 0.00082 19.9 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Harakiri PF15196.1 EGO54666.1 - 0.048 13.9 0.1 0.048 13.9 0.1 2.5 2 1 0 2 2 2 0 Activator of apoptosis harakiri Prenyltrans PF00432.16 EGO54667.1 - 3.2e-38 128.9 18.6 2.8e-10 39.5 0.1 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGO54667.1 - 1.6e-21 76.7 0.0 1.4e-16 60.9 0.0 3.9 1 1 3 4 4 4 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGO54667.1 - 4.1e-06 26.7 0.0 4.4e-05 23.4 0.0 2.3 2 1 0 2 2 2 1 Prenyltransferase-like DUF1044 PF06296.7 EGO54667.1 - 0.19 11.5 0.1 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1044) Zn_clus PF00172.13 EGO54670.1 - 0.0032 17.3 7.7 0.0069 16.2 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ubiquitin PF00240.18 EGO54671.1 - 2.3e-137 446.5 26.1 4.1e-34 115.7 0.9 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EGO54671.1 - 1.1e-78 258.9 24.2 2.6e-19 68.6 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGO54671.1 - 1.9e-25 88.8 12.8 6e-05 23.2 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGO54671.1 - 4.6e-22 78.4 1.0 0.00075 19.2 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing DUF2407 PF10302.4 EGO54671.1 - 1.9e-15 56.8 3.1 0.043 14.0 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EGO54671.1 - 4.7e-15 55.4 4.2 0.058 13.2 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EGO54671.1 - 1.4e-10 41.0 0.0 1.5 8.8 0.0 4.6 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EGO54671.1 - 1.3e-07 31.4 7.2 1.9 8.4 0.1 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 EGO54671.1 - 2.2e-05 23.6 0.8 2.9 6.9 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase Big_3_3 PF13750.1 EGO54671.1 - 3.5e-05 23.2 0.1 21 4.5 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) FlgD_ig PF13860.1 EGO54671.1 - 0.0001 21.9 5.1 16 5.3 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 EGO54671.1 - 0.00026 19.4 15.6 1.5 7.0 0.3 5.7 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain USP7_C2 PF14533.1 EGO54671.1 - 0.00059 19.3 6.0 14 4.9 0.1 3.9 1 1 0 4 4 4 0 Ubiquitin-specific protease C-terminal DUF3861 PF12977.2 EGO54671.1 - 0.00059 19.8 6.9 23 5.1 0.1 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) RA PF00788.18 EGO54671.1 - 0.0017 18.7 0.1 1.1e+02 3.3 0.0 4.3 4 0 0 4 4 4 0 Ras association (RalGDS/AF-6) domain ACT_4 PF13291.1 EGO54671.1 - 0.0019 18.4 1.3 91 3.4 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF493 PF04359.9 EGO54671.1 - 0.0031 17.8 0.3 1.2e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Sortase PF04203.8 EGO54671.1 - 0.0073 15.8 2.0 32 4.1 0.0 3.9 2 1 2 4 4 4 0 Sortase family CTDII PF01556.13 EGO54671.1 - 0.014 15.3 16.0 5 7.0 0.2 4.3 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 EGO54671.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 EGO54671.1 - 0.049 13.6 10.6 29 4.7 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain DUF3781 PF12636.2 EGO54671.1 - 0.19 11.7 8.6 67 3.5 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) FERM_N PF09379.5 EGO54671.1 - 0.19 11.7 14.3 40 4.3 0.2 5.9 4 4 0 4 4 4 0 FERM N-terminal domain PI3K_p85B PF02192.11 EGO54671.1 - 1.6 8.1 8.7 82 2.7 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Myosin_N PF02736.14 EGO54671.1 - 2.9 7.6 8.3 1e+02 2.7 0.1 4.3 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain FliL PF03748.9 EGO54671.1 - 3.3 7.7 6.8 2e+02 2.0 0.1 4.0 4 0 0 4 4 4 0 Flagellar basal body-associated protein FliL BRAP2 PF07576.7 EGO54672.1 - 2.6e-19 68.8 0.0 5.7e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EGO54672.1 - 1.2e-18 66.9 5.3 5.2e-18 64.9 3.6 2.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EGO54672.1 - 3.5e-08 33.1 9.7 3.5e-08 33.1 6.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EGO54672.1 - 0.00012 21.6 7.1 0.00012 21.6 4.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGO54672.1 - 0.00068 19.2 8.4 0.002 17.7 5.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO54672.1 - 0.0044 16.6 6.3 0.0044 16.6 4.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGO54672.1 - 0.2 11.3 7.6 0.061 13.0 1.3 2.7 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EGO54672.1 - 0.47 10.5 20.1 0.017 15.1 6.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGO54672.1 - 1.5 9.0 13.0 0.051 13.6 4.2 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger Fungal_trans PF04082.13 EGO54673.1 - 3.4e-24 85.1 0.0 6.8e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO54673.1 - 0.02 14.8 4.8 0.043 13.7 3.3 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_7 PF13508.1 EGO54674.1 - 3.2e-09 36.8 0.0 1e-07 31.9 0.0 3.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO54674.1 - 7.3e-09 35.5 0.0 1.7e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Zn_clus PF00172.13 EGO54674.1 - 2e-08 34.0 8.1 4.3e-08 32.9 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_10 PF13673.1 EGO54674.1 - 9.7e-06 25.6 0.1 0.00026 21.0 0.0 2.8 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO54674.1 - 0.00015 21.4 0.0 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EGO54674.1 - 0.013 15.3 0.0 0.042 13.6 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans_2 PF11951.3 EGO54674.1 - 0.014 14.0 2.2 0.028 13.0 1.5 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short PF00106.20 EGO54676.1 - 0.00045 20.1 0.1 0.0068 16.3 0.0 2.6 2 1 1 3 3 3 1 short chain dehydrogenase MFS_1 PF07690.11 EGO54677.1 - 4e-17 61.9 41.3 4.6e-17 61.7 27.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EGO54677.1 - 0.012 15.4 0.9 0.042 13.6 0.1 2.4 2 0 0 2 2 2 0 MFS_1 like family UCR_hinge PF02320.11 EGO54678.1 - 1.5e-28 98.5 5.2 2.8e-28 97.6 3.6 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Myc_N PF01056.13 EGO54678.1 - 0.065 12.3 11.9 0.071 12.2 8.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Herpes_TAF50 PF03326.8 EGO54678.1 - 0.14 11.1 6.6 0.15 11.0 4.6 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Daxx PF03344.10 EGO54678.1 - 0.47 8.8 17.1 0.5 8.7 11.9 1.0 1 0 0 1 1 1 0 Daxx Family TLP-20 PF06088.6 EGO54678.1 - 0.53 9.9 3.9 0.63 9.6 2.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF1510 PF07423.6 EGO54678.1 - 1.4 8.2 12.9 1.6 8.0 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2360 PF10152.4 EGO54678.1 - 1.6 8.9 8.4 2 8.7 5.8 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DHHW PF14286.1 EGO54678.1 - 1.6 7.9 5.9 1.8 7.7 4.1 1.0 1 0 0 1 1 1 0 DHHW protein DUF3530 PF12048.3 EGO54678.1 - 2.1 7.2 11.5 2.3 7.1 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) CDC45 PF02724.9 EGO54678.1 - 2.3 6.1 6.2 2.3 6.1 4.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF740 PF05340.7 EGO54678.1 - 3 6.1 9.5 3.2 5.9 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Pox_Ag35 PF03286.9 EGO54678.1 - 4 6.9 11.4 4.7 6.6 7.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Presenilin PF01080.12 EGO54678.1 - 4.5 5.9 7.6 5.2 5.7 5.3 1.0 1 0 0 1 1 1 0 Presenilin EBV-NA3 PF05009.7 EGO54678.1 - 4.6 6.4 9.4 6.2 5.9 6.5 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RR_TM4-6 PF06459.7 EGO54678.1 - 5 6.9 13.9 5.6 6.7 9.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CT47 PF15623.1 EGO54678.1 - 5.1 6.7 28.3 6.2 6.4 19.6 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Nop14 PF04147.7 EGO54678.1 - 5.2 4.8 14.4 5.5 4.7 10.0 1.0 1 0 0 1 1 1 0 Nop14-like family Ycf1 PF05758.7 EGO54678.1 - 5.2 4.6 5.3 5.1 4.6 3.7 1.0 1 0 0 1 1 1 0 Ycf1 MSP1_C PF07462.6 EGO54678.1 - 7.9 4.7 6.8 8.2 4.6 4.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Spore_coat_CotO PF14153.1 EGO54678.1 - 8 5.8 11.5 9.2 5.6 8.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO WWbp PF10349.4 EGO54679.1 - 1.2e-13 51.9 2.0 1.2e-13 51.9 1.4 2.0 2 0 0 2 2 2 1 WW-domain ligand protein Drf_GBD PF06371.8 EGO54680.1 - 1.2e-14 54.1 2.9 8.2e-09 35.0 0.0 2.9 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Suc_Fer-like PF06999.7 EGO54681.1 - 2.9e-34 119.1 0.0 3.2e-33 115.6 0.0 2.0 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Fer4_13 PF13370.1 EGO54681.1 - 0.0061 16.9 0.1 0.016 15.6 0.1 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Acyltransferase PF01553.16 EGO54682.1 - 1.5e-10 40.6 0.0 4.3e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Fapy_DNA_glyco PF01149.19 EGO54683.1 - 7.6e-28 97.2 0.0 1.5e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EGO54683.1 - 2.1e-22 78.6 0.0 4.3e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 EGO54683.1 - 0.0026 16.3 0.4 0.0041 15.7 0.0 1.4 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DHBP_synthase PF00926.14 EGO54685.1 - 9.4e-74 246.8 0.0 5.3e-73 244.3 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Methyltransf_23 PF13489.1 EGO54686.1 - 3e-21 75.8 0.0 4.6e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO54686.1 - 7.9e-17 61.2 0.0 1e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO54686.1 - 2.8e-16 59.7 0.0 4.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO54686.1 - 5.3e-16 59.1 0.0 7.5e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO54686.1 - 1.3e-14 54.4 0.0 3.1e-14 53.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO54686.1 - 1.5e-08 34.9 0.0 2.4e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO54686.1 - 6.9e-08 32.5 0.0 2.4e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO54686.1 - 3.5e-07 29.6 0.0 5.1e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EGO54686.1 - 0.00011 21.4 0.0 0.00053 19.1 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 EGO54686.1 - 0.0019 16.9 0.0 0.0028 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 EGO54686.1 - 0.027 13.8 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DREV PF05219.7 EGO54686.1 - 0.12 11.2 0.0 0.27 10.0 0.0 1.5 1 1 0 1 1 1 0 DREV methyltransferase Peptidase_S10 PF00450.17 EGO54687.1 - 4.6e-74 250.0 0.0 2.3e-73 247.7 0.0 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase RXT2_N PF08595.6 EGO54688.1 - 7.7e-44 149.0 0.0 7.7e-44 149.0 0.0 2.2 2 0 0 2 2 2 1 RXT2-like, N-terminal Tyrosinase PF00264.15 EGO54689.1 - 2.7e-43 148.7 5.2 4e-43 148.1 0.0 2.3 2 0 0 2 2 2 1 Common central domain of tyrosinase Mem_trans PF03547.13 EGO54689.1 - 0.33 9.1 1.0 0.5 8.5 0.7 1.2 1 0 0 1 1 1 0 Membrane transport protein Macoilin PF09726.4 EGO54689.1 - 0.49 8.6 8.8 0.68 8.1 6.1 1.1 1 0 0 1 1 1 0 Transmembrane protein DHDPS PF00701.17 EGO54690.1 - 9.4e-41 139.2 0.0 1.2e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF2270 PF10028.4 EGO54692.1 - 0.088 12.2 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) Glyco_hydro_16 PF00722.16 EGO54693.1 - 3.6e-45 153.5 2.5 8.9e-45 152.2 1.7 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SIR2 PF02146.12 EGO54695.1 - 5.1e-41 140.3 0.0 1.1e-40 139.2 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Dfp1_Him1_M PF08630.5 EGO54697.1 - 1.5e-43 147.5 0.0 3.1e-43 146.5 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EGO54697.1 - 8.4e-25 86.1 0.2 1.4e-24 85.4 0.2 1.4 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 EGO54697.1 - 0.0016 18.2 0.0 0.0043 16.8 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EGO54697.1 - 0.011 15.9 0.0 0.03 14.4 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Peptidase_M24 PF00557.19 EGO54698.1 - 9.7e-49 165.7 0.0 1.4e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EGO54698.1 - 9.9e-35 118.8 0.0 1.9e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HLH PF00010.21 EGO54699.1 - 8.2e-18 63.8 0.5 8e-17 60.6 0.0 2.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain APG12 PF04110.8 EGO54700.1 - 1.3e-24 86.1 0.0 1.7e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EGO54700.1 - 0.0002 21.3 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.10 EGO54701.1 - 3.3e-105 350.8 0.4 4.2e-105 350.5 0.3 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EGO54701.1 - 7.9e-10 38.3 2.5 3.7e-09 36.1 1.8 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase NanE PF04131.9 EGO54701.1 - 0.078 11.9 0.3 4.5 6.2 0.1 2.7 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase UQ_con PF00179.21 EGO54703.1 - 1.9e-36 124.5 0.1 2.5e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pectinesterase PF01095.14 EGO54704.1 - 1.8e-49 167.9 2.2 2.4e-49 167.5 1.5 1.0 1 0 0 1 1 1 1 Pectinesterase Glyco_hydro_61 PF03443.9 EGO54705.1 - 3.1e-85 285.4 0.5 4.8e-85 284.7 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 YTH PF04146.10 EGO54706.1 - 1.3e-40 138.2 0.3 2.1e-40 137.5 0.2 1.4 1 0 0 1 1 1 1 YT521-B-like domain p450 PF00067.17 EGO54707.1 - 7.3e-26 90.7 0.0 9.1e-26 90.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DRMBL PF07522.9 EGO54708.1 - 2e-06 27.8 0.0 5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EGO54708.1 - 0.0014 18.2 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Exo_endo_phos_2 PF14529.1 EGO54709.1 - 0.017 14.7 1.9 0.56 9.8 1.3 2.3 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Glyco_hydro_32N PF00251.15 EGO54709.1 - 0.018 14.4 0.1 0.094 12.0 0.0 1.9 1 1 1 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.9 EGO54709.1 - 0.021 13.9 3.4 0.072 12.1 2.5 1.8 1 1 1 2 2 2 0 Glycosyl hydrolases family 43 Velvet PF11754.3 EGO54710.1 - 1.1e-56 191.6 0.0 1.6e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Velvet factor RRP14 PF15459.1 EGO54713.1 - 0.098 12.7 1.5 0.17 11.9 1.1 1.3 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 DUF572 PF04502.8 EGO54714.1 - 7.9e-79 265.2 0.0 9.6e-79 264.9 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) GBP_C PF02841.9 EGO54714.1 - 0.24 10.5 6.0 0.39 9.8 4.1 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Mannosyl_trans2 PF04188.8 EGO54715.1 - 5.3e-60 203.5 0.1 8.7e-60 202.8 0.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) V-SNARE PF05008.10 EGO54716.1 - 1.8e-24 85.7 3.6 3.8e-24 84.6 2.5 1.6 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EGO54716.1 - 1.6e-16 60.0 0.8 1.6e-16 60.0 0.6 2.5 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EGO54716.1 - 0.0075 15.9 1.6 0.011 15.4 0.4 1.9 2 0 0 2 2 2 1 Sec20 Cor1 PF04803.7 EGO54716.1 - 0.0088 15.7 1.4 0.017 14.9 0.0 2.1 2 1 0 2 2 2 1 Cor1/Xlr/Xmr conserved region Unstab_antitox PF09720.5 EGO54716.1 - 0.019 14.6 0.2 0.05 13.2 0.1 1.7 1 0 0 1 1 1 0 Putative addiction module component Spc7 PF08317.6 EGO54716.1 - 0.021 13.4 3.2 0.37 9.3 0.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Use1 PF09753.4 EGO54716.1 - 0.022 14.1 5.2 0.097 12.0 0.1 2.5 1 1 1 2 2 2 0 Membrane fusion protein Use1 Fusion_gly PF00523.13 EGO54716.1 - 0.023 12.8 1.7 0.094 10.7 0.2 2.1 2 0 0 2 2 2 0 Fusion glycoprotein F0 L31 PF09784.4 EGO54716.1 - 0.04 13.9 0.4 1.2 9.2 0.1 2.4 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 Tektin PF03148.9 EGO54716.1 - 0.059 11.9 3.7 1.9 6.9 0.2 2.2 2 0 0 2 2 2 0 Tektin family Synaptobrevin PF00957.16 EGO54716.1 - 0.09 12.3 2.5 0.24 11.0 1.4 2.0 1 1 1 2 2 2 0 Synaptobrevin Mnd1 PF03962.10 EGO54716.1 - 0.28 10.8 3.6 0.24 11.0 0.3 1.9 1 1 1 2 2 2 0 Mnd1 family TBCA PF02970.11 EGO54716.1 - 0.72 9.9 6.7 1.7 8.7 0.0 3.0 3 1 0 3 3 3 0 Tubulin binding cofactor A Myosin_tail_1 PF01576.14 EGO54716.1 - 0.75 7.4 8.2 0.81 7.3 0.4 2.1 2 0 0 2 2 2 0 Myosin tail HET PF06985.6 EGO54718.1 - 1.9e-25 89.6 0.0 2.8e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_2_C PF02836.12 EGO54719.1 - 2.7e-101 338.4 0.0 4.3e-101 337.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 EGO54719.1 - 1.7e-50 171.5 0.1 2.6e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 EGO54719.1 - 2.1e-49 167.2 0.3 4.1e-49 166.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EGO54719.1 - 8.5e-10 39.0 0.0 2.4e-09 37.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EGO54719.1 - 0.0017 18.5 0.0 0.0075 16.5 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain BNR PF02012.15 EGO54720.1 - 1.4e-14 51.4 29.7 0.21 11.5 0.1 10.4 9 0 0 9 9 9 8 BNR/Asp-box repeat CBM_1 PF00734.13 EGO54720.1 - 3.5e-14 52.1 10.5 1e-13 50.6 7.3 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Kelch_6 PF13964.1 EGO54720.1 - 2 8.7 8.0 5.7 7.2 0.0 4.4 4 1 0 4 4 4 0 Kelch motif Nop14 PF04147.7 EGO54721.1 - 6.6 4.5 8.5 11 3.7 5.9 1.3 1 0 0 1 1 1 0 Nop14-like family DUF829 PF05705.9 EGO54722.1 - 1.5e-38 132.8 0.7 1.2e-23 84.0 0.0 3.0 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) Transposase_23 PF03017.9 EGO54723.1 - 0.051 13.0 0.0 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 TNP1/EN/SPM transposase DUF4448 PF14610.1 EGO54724.1 - 0.0044 16.5 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 EGO54724.1 - 0.11 11.8 0.9 0.27 10.5 0.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.1 EGO54724.1 - 2.3 7.9 6.5 0.16 11.7 0.9 1.7 2 0 0 2 2 2 0 TMEM154 protein family LAMTOR PF15454.1 EGO54725.1 - 1.9e-15 56.8 0.6 3e-15 56.2 0.5 1.2 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator RPEL PF02755.10 EGO54728.1 - 0.00051 19.2 0.1 0.0025 17.0 0.0 2.0 2 0 0 2 2 2 1 RPEL repeat Adeno_PIX PF03955.9 EGO54729.1 - 1.5 9.3 7.6 2 8.9 5.3 1.3 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Paramyxo_PNT PF13825.1 EGO54729.1 - 4.1 6.5 12.5 4.3 6.4 8.7 1.0 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus zf-C2H2_jaz PF12171.3 EGO54730.1 - 0.00038 20.4 0.0 0.00067 19.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Hid1 PF12722.2 EGO54730.1 - 0.34 8.5 1.3 0.48 8.0 0.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAXIP1_C PF15364.1 EGO54730.1 - 1.8 8.4 21.4 0.036 13.9 3.5 2.9 3 0 0 3 3 3 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF2802 PF10975.3 EGO54730.1 - 8.4 6.2 10.9 16 5.3 3.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) Med7 PF05983.6 EGO54731.1 - 1e-46 158.7 0.0 1.2e-46 158.4 0.0 1.0 1 0 0 1 1 1 1 MED7 protein SPOC PF07744.8 EGO54732.1 - 9.6e-20 71.2 0.0 2e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.9 EGO54732.1 - 6.6e-17 61.6 0.0 1.4e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 EGO54732.1 - 4.3e-09 35.9 8.0 9.2e-09 34.8 5.6 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EGO54732.1 - 0.23 10.8 2.5 0.43 9.9 1.7 1.5 1 0 0 1 1 1 0 PHD-finger Proteasome PF00227.21 EGO54733.1 - 7e-61 204.8 0.1 8.6e-61 204.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGO54733.1 - 2.8e-14 52.1 0.4 6.9e-14 50.8 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EGO54733.1 - 0.16 11.2 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit PAP2 PF01569.16 EGO54734.1 - 3.1e-25 88.3 0.2 3.1e-25 88.3 0.2 1.7 2 0 0 2 2 2 1 PAP2 superfamily WD40 PF00400.27 EGO54736.1 - 5e-55 181.5 15.6 1.1e-08 34.5 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EGO54736.1 - 7.1e-14 51.2 0.2 1.4e-13 50.2 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO54736.1 - 3.5e-12 45.6 0.6 9.5e-12 44.2 0.1 2.0 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 EGO54736.1 - 2.3e-05 22.7 8.2 0.38 8.8 0.0 5.5 2 2 2 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EGO54736.1 - 0.0011 18.4 1.3 0.36 10.2 0.3 3.3 1 1 1 2 2 2 1 PQQ-like domain PRANC PF09372.5 EGO54736.1 - 0.0045 16.9 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 PRANC domain CPSF_A PF03178.10 EGO54736.1 - 0.051 12.6 0.0 0.61 9.1 0.0 2.5 3 0 0 3 3 3 0 CPSF A subunit region HORMA PF02301.13 EGO54738.1 - 9e-06 25.3 0.6 5.5e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 HORMA domain DASH_Ask1 PF08655.5 EGO54738.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Ask1 NTP_transferase PF00483.18 EGO54739.1 - 2.8e-28 98.8 0.0 3.9e-28 98.3 0.0 1.3 1 1 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EGO54739.1 - 2.6e-12 45.6 3.6 1.5e-05 24.2 0.0 3.7 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EGO54739.1 - 1.3e-05 25.2 0.0 2.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EGO54739.1 - 0.0083 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Dynamin_N PF00350.18 EGO54740.1 - 4.2e-22 78.7 0.0 5.3e-21 75.1 0.0 2.6 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGO54740.1 - 1.2e-12 47.2 1.9 8.4e-07 28.0 0.1 2.4 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 EGO54740.1 - 0.0016 18.3 0.0 0.0016 18.3 0.0 2.7 3 1 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGO54740.1 - 0.0087 16.0 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.1 EGO54740.1 - 0.009 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EGO54740.1 - 0.015 15.8 0.0 0.043 14.3 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 EGO54740.1 - 0.018 15.3 0.1 0.11 12.8 0.0 2.3 3 0 0 3 3 3 0 ABC transporter AAA_29 PF13555.1 EGO54740.1 - 0.026 14.0 0.1 0.06 12.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 EGO54740.1 - 0.077 12.4 0.0 9.9 5.6 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EGO54740.1 - 0.18 12.1 1.9 16 5.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain WSC PF01822.14 EGO54741.1 - 2.4e-72 238.8 47.8 2.4e-21 75.4 3.0 4.3 4 0 0 4 4 4 4 WSC domain AAA_4 PF04326.9 EGO54741.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Divergent AAA domain Amino_oxidase PF01593.19 EGO54743.1 - 5.1e-20 71.9 0.0 5.7e-11 42.1 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGO54743.1 - 4.6e-09 36.1 1.1 1.2e-08 34.8 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO54743.1 - 5.1e-09 35.4 0.4 8.2e-09 34.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EGO54743.1 - 3.8e-08 32.7 0.1 6.6e-08 31.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EGO54743.1 - 5.9e-07 28.7 0.0 1.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO54743.1 - 1e-05 25.6 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO54743.1 - 1.2e-05 24.6 0.0 1.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGO54743.1 - 0.0001 21.5 0.4 0.00015 20.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EGO54743.1 - 0.00015 21.6 0.0 0.00042 20.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO54743.1 - 0.00053 18.5 0.4 0.0008 17.9 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EGO54743.1 - 0.0019 17.1 0.2 0.0028 16.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EGO54743.1 - 0.003 16.5 0.0 0.0047 15.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EGO54743.1 - 0.0047 17.3 0.1 0.0091 16.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO54743.1 - 0.094 12.4 0.0 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Beta-lactamase PF00144.19 EGO54745.1 - 3.6e-34 118.2 0.0 1.3e-28 100.0 0.0 2.6 2 1 0 2 2 2 2 Beta-lactamase DUF3471 PF11954.3 EGO54745.1 - 0.11 12.3 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) AIG1 PF04548.11 EGO54746.1 - 6.4e-06 25.4 0.0 1.7e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.18 EGO54746.1 - 6.4e-06 26.1 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGO54746.1 - 0.00061 19.0 0.1 0.0015 17.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EGO54746.1 - 0.02 14.2 0.1 0.03 13.5 0.1 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_33 PF13671.1 EGO54746.1 - 0.031 14.1 0.0 0.085 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EGO54746.1 - 0.061 13.1 0.7 0.061 13.1 0.5 1.9 2 1 0 2 2 2 0 Domain of unknown function DUF87 TroA PF01297.12 EGO54746.1 - 0.097 11.8 0.0 2.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Periplasmic solute binding protein family DUF1664 PF07889.7 EGO54746.1 - 0.12 12.1 0.0 0.41 10.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_17 PF13207.1 EGO54746.1 - 0.13 13.0 0.1 0.39 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF3040 PF11239.3 EGO54746.1 - 0.29 11.2 4.2 0.21 11.6 1.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) FadA PF09403.5 EGO54746.1 - 0.34 10.9 2.4 0.98 9.4 1.7 1.7 1 1 0 1 1 1 0 Adhesion protein FadA DUF1319 PF07028.6 EGO54746.1 - 0.54 10.4 2.2 0.43 10.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) Dynamin_N PF00350.18 EGO54746.1 - 0.71 9.6 5.8 4.7 6.9 0.5 2.9 2 2 1 3 3 3 0 Dynamin family AAA_23 PF13476.1 EGO54747.1 - 0.0011 19.3 9.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain ImcF-related_N PF14331.1 EGO54747.1 - 0.012 14.5 2.5 0.018 13.9 1.7 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain AAA_29 PF13555.1 EGO54747.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain UT PF03253.9 EGO54747.1 - 0.042 12.7 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Urea transporter FKBP_N PF01346.13 EGO54747.1 - 0.058 13.4 3.8 0.11 12.4 2.6 1.5 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF87 PF01935.12 EGO54747.1 - 0.077 12.7 9.7 0.12 12.1 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_33 PF13671.1 EGO54747.1 - 0.085 12.7 2.5 0.29 10.9 0.2 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EGO54747.1 - 0.093 12.5 3.6 0.32 10.8 0.2 2.3 2 0 0 2 2 2 0 Dynamin family MobB PF03205.9 EGO54747.1 - 0.11 12.2 0.2 0.29 10.8 0.2 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EGO54747.1 - 0.2 12.1 1.4 0.24 11.8 0.1 1.9 2 1 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 EGO54747.1 - 0.21 12.3 1.7 0.9 10.3 0.3 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EGO54747.1 - 0.25 10.1 4.0 0.5 9.1 0.1 2.4 2 1 0 2 2 2 0 NB-ARC domain PEPcase_2 PF14010.1 EGO54747.1 - 0.29 9.4 2.9 0.4 8.9 2.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Ferritin PF00210.19 EGO54747.1 - 0.8 9.4 6.9 1.8 8.3 4.8 1.6 1 1 0 1 1 1 0 Ferritin-like domain IncA PF04156.9 EGO54747.1 - 0.9 9.1 11.4 1.4 8.5 7.9 1.3 1 0 0 1 1 1 0 IncA protein ATP_bind_1 PF03029.12 EGO54747.1 - 3.5 7.0 6.6 0.54 9.7 1.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 EGO54747.1 - 3.9 7.7 9.6 66 3.7 6.7 2.5 1 1 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 EGO54748.1 - 5.3e-47 159.7 0.1 8.4e-47 159.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EGO54748.1 - 3.1e-38 129.9 5.8 5.1e-38 129.2 4.0 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EGO54748.1 - 1.6e-17 63.1 0.0 3.1e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGO54748.1 - 8.5e-06 25.8 0.0 2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EGO54748.1 - 3.7e-05 23.4 0.0 0.00028 20.6 0.0 2.4 2 1 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EGO54748.1 - 6.9e-05 22.7 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EGO54748.1 - 0.00012 21.4 0.1 0.00038 19.8 0.0 1.8 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 EGO54748.1 - 0.0057 15.9 0.2 0.017 14.3 0.0 1.9 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EGO54748.1 - 0.094 13.2 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein MIT PF04212.13 EGO54749.1 - 3.4e-13 49.2 0.6 6.3e-13 48.4 0.4 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Methyltransf_23 PF13489.1 EGO54750.1 - 4.4e-20 72.0 0.0 8.9e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO54750.1 - 3.6e-11 42.8 0.0 1.2e-10 41.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO54750.1 - 1.3e-08 35.2 0.0 2.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO54750.1 - 6.7e-07 29.8 0.0 5.3e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO54750.1 - 2.3e-06 27.9 0.0 9.5e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO54750.1 - 0.0049 16.0 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EGO54750.1 - 0.0072 16.3 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EGO54750.1 - 0.012 14.6 0.0 0.028 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 EGO54750.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EGO54750.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EGO54750.1 - 0.071 12.4 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EGO54750.1 - 0.2 10.7 0.0 1.7 7.6 0.0 2.2 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Glyco_hydro_10 PF00331.15 EGO54751.1 - 1.7e-102 342.7 0.8 1.9e-102 342.5 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 GMC_oxred_N PF00732.14 EGO54752.1 - 1.6e-26 93.1 0.0 3e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO54752.1 - 1.1e-21 77.6 0.1 2e-21 76.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EGO54752.1 - 3e-09 36.2 0.1 0.0006 18.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGO54752.1 - 4.5e-08 32.3 0.2 0.00031 19.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO54752.1 - 0.00013 21.9 0.0 0.00036 20.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGO54752.1 - 0.00033 20.7 0.0 0.0044 17.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DOMON PF03351.12 EGO54752.1 - 0.0011 18.8 0.1 0.0032 17.4 0.1 1.7 1 0 0 1 1 1 1 DOMON domain HI0933_like PF03486.9 EGO54752.1 - 0.0028 16.1 0.1 0.0044 15.5 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EGO54752.1 - 0.0039 17.1 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO54752.1 - 0.021 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EGO54752.1 - 0.027 13.5 0.1 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EGO54752.1 - 0.043 12.7 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EGO54752.1 - 0.064 12.3 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGO54752.1 - 0.18 12.2 0.0 1 9.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Arrestin_N PF00339.24 EGO54753.1 - 0.00074 19.3 0.1 0.0032 17.2 0.1 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain BTB PF00651.26 EGO54754.1 - 2.5e-08 33.9 0.0 5.1e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EGO54755.1 - 0.0056 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain HET PF06985.6 EGO54756.1 - 2.3e-15 56.9 6.4 6.5e-14 52.2 1.8 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EGO54757.1 - 2.5e-25 88.6 0.0 2.6e-09 37.2 0.0 5.3 5 1 0 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EGO54757.1 - 3.4e-24 83.3 1.9 1e-06 28.2 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 EGO54757.1 - 6.4e-15 54.8 3.0 0.00016 21.8 0.0 6.8 6 1 0 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGO54757.1 - 2.1e-14 53.5 1.3 5.8e-06 26.6 0.0 6.3 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO54757.1 - 3.1e-12 45.4 6.3 1.8 9.0 0.1 8.6 8 2 0 8 8 8 4 Ankyrin repeat But2 PF09792.4 EGO54758.1 - 0.018 14.8 1.1 0.039 13.7 0.8 1.6 1 1 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain CAP59_mtransfer PF11735.3 EGO54759.1 - 3.8e-67 226.0 0.0 5.3e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF3439 PF11921.3 EGO54759.1 - 0.039 13.7 1.6 0.068 12.9 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF4328 PF14219.1 EGO54760.1 - 0.088 12.0 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) 4HBT_3 PF13622.1 EGO54762.1 - 0.077 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily CIAPIN1 PF05093.8 EGO54763.1 - 0.012 15.6 1.0 0.019 15.0 0.7 1.3 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis FYVE PF01363.16 EGO54763.1 - 0.041 13.7 2.4 0.08 12.8 1.7 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-H2C2_2 PF13465.1 EGO54764.1 - 4.4e-06 26.7 7.9 0.0019 18.3 0.6 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EGO54764.1 - 9.1e-06 25.7 12.7 0.025 14.9 0.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO54764.1 - 0.0015 18.7 14.4 0.14 12.5 0.4 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EGO54764.1 - 0.21 11.8 10.2 0.35 11.2 0.1 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Peptidase_M35 PF02102.10 EGO54765.1 - 2.4e-30 105.3 14.3 3e-30 105.0 9.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EGO54765.1 - 3.6e-10 40.5 0.6 6.9e-10 39.6 0.4 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase DUF4352 PF11611.3 EGO54765.1 - 0.0049 16.9 0.0 0.016 15.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4352) HRXXH PF13933.1 EGO54765.1 - 0.049 13.0 0.3 0.049 13.0 0.2 1.7 2 0 0 2 2 2 0 Putative peptidase family Cutinase PF01083.17 EGO54767.1 - 2e-56 190.5 9.1 2.6e-56 190.1 6.3 1.2 1 0 0 1 1 1 1 Cutinase CBM_1 PF00734.13 EGO54767.1 - 4.2e-12 45.4 19.8 4.2e-12 45.4 13.7 4.7 4 1 1 5 5 5 1 Fungal cellulose binding domain PE-PPE PF08237.6 EGO54767.1 - 2.4e-05 23.8 0.1 3.4e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 EGO54767.1 - 0.00068 19.2 0.1 0.0014 18.2 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGO54767.1 - 0.00074 19.4 0.0 0.0009 19.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO54767.1 - 0.01 15.5 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cation_efflux PF01545.16 EGO54769.1 - 7.7e-26 90.8 2.0 1e-25 90.3 1.4 1.1 1 0 0 1 1 1 1 Cation efflux family DUF707 PF05212.7 EGO54769.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF707) Beta_propel PF09826.4 EGO54770.1 - 0.16 10.2 0.0 6.2 5.0 0.0 2.2 2 0 0 2 2 2 0 Beta propeller domain E1-E2_ATPase PF00122.15 EGO54772.1 - 5.3e-59 199.0 0.3 1.3e-58 197.7 0.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGO54772.1 - 9.5e-49 165.3 2.1 9.5e-49 165.3 1.5 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGO54772.1 - 2.5e-27 96.6 0.0 7.9e-27 95.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO54772.1 - 2.5e-20 72.2 0.0 5.1e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGO54772.1 - 2e-14 54.2 0.0 4e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGO54772.1 - 1.6e-09 37.0 0.1 7.2e-08 31.7 0.0 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGO54772.1 - 4.4e-07 29.7 0.3 3.8e-05 23.3 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EGO54772.1 - 0.024 14.5 2.5 0.67 9.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) Hexapep PF00132.19 EGO54773.1 - 5.5e-17 60.4 15.6 9.9e-12 43.8 6.0 2.7 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGO54773.1 - 7.3e-14 51.0 12.8 3e-10 39.4 5.0 2.7 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EGO54773.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Maltose acetyltransferase Macoilin PF09726.4 EGO54773.1 - 0.073 11.3 12.0 0.097 10.9 8.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Gemini_C4 PF01492.12 EGO54774.1 - 0.013 15.1 1.1 0.033 13.9 0.8 1.6 1 0 0 1 1 1 0 Geminivirus C4 protein Pex14_N PF04695.8 EGO54774.1 - 7.4 6.6 7.5 1.1 9.3 1.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region XFP_N PF09364.5 EGO54775.1 - 2e-154 513.7 0.0 2.7e-154 513.3 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 EGO54775.1 - 1.1e-68 230.3 0.0 2e-68 229.5 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EGO54775.1 - 1.8e-66 223.4 0.0 3.8e-66 222.3 0.0 1.6 2 0 0 2 2 2 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 EGO54775.1 - 0.0074 15.8 0.1 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Alveol-reg_P311 PF11092.3 EGO54776.1 - 0.086 12.8 0.4 0.12 12.3 0.3 1.3 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) Phage_HK97_TLTM PF06120.6 EGO54777.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Tail length tape measure protein DUF2975 PF11188.3 EGO54777.1 - 0.17 11.6 2.0 0.16 11.7 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) Pkinase PF00069.20 EGO54780.1 - 1.2e-10 40.9 0.0 3.1e-08 33.0 0.0 3.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO54780.1 - 3.3e-05 23.0 0.1 0.092 11.7 0.1 3.3 2 1 0 2 2 2 2 Protein tyrosine kinase Ank PF00023.25 EGO54781.1 - 9.4e-22 75.6 0.1 4.2e-06 26.2 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EGO54781.1 - 1.7e-20 73.1 0.0 4.1e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO54781.1 - 2.2e-18 66.2 0.0 1.7e-09 37.9 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO54781.1 - 2.6e-15 54.9 0.0 0.0028 17.7 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EGO54781.1 - 6.4e-14 51.6 0.0 6.4e-08 32.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) FAR1 PF03101.10 EGO54781.1 - 2.1e-07 31.3 0.4 2.1e-07 31.3 0.3 3.5 4 1 0 4 4 4 1 FAR1 DNA-binding domain Ferritin_2 PF13668.1 EGO54782.1 - 4.4e-17 62.3 0.1 6.4e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain SR-25 PF10500.4 EGO54783.1 - 0.00078 18.9 4.9 0.00078 18.9 3.4 3.2 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein DUF1675 PF07897.6 EGO54783.1 - 1.2 8.8 29.5 0.6 9.9 11.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) DUF572 PF04502.8 EGO54783.1 - 10 5.2 24.1 1.1 8.4 9.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Ank_4 PF13637.1 EGO54785.1 - 0.00023 21.6 0.1 0.32 11.5 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO54785.1 - 0.015 15.6 0.0 0.24 11.7 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) NPV_P10 PF05531.7 EGO54785.1 - 0.019 15.2 1.5 0.019 15.2 1.0 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Ank PF00023.25 EGO54785.1 - 0.027 14.3 0.2 1.2 9.0 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeat Baculo_p24 PF05073.7 EGO54785.1 - 0.23 11.0 3.8 1.1 8.8 0.4 2.6 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Glyco_transf_25 PF01755.12 EGO54786.1 - 5.3e-08 32.7 0.0 8.4e-08 32.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Barstar PF01337.13 EGO54786.1 - 0.12 12.1 0.0 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 Barstar (barnase inhibitor) Glyco_hydro_114 PF03537.8 EGO54788.1 - 2.4e-21 75.3 0.0 4.7e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 ETRAMP PF09716.5 EGO54788.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Spherulin4 PF12138.3 EGO54789.1 - 7.7e-102 340.0 0.6 6.1e-86 287.9 0.0 3.0 2 1 1 3 3 3 3 Spherulation-specific family 4 Epimerase PF01370.16 EGO54791.1 - 1.7e-35 122.6 0.0 1e-34 120.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EGO54791.1 - 2.2e-16 59.5 1.1 2.9e-16 59.1 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EGO54791.1 - 1e-08 34.2 0.2 2.1e-06 26.6 0.1 2.4 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGO54791.1 - 9.7e-07 27.9 0.1 5.2e-06 25.5 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EGO54791.1 - 7.9e-06 24.9 0.3 0.00023 20.1 0.0 2.2 1 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGO54791.1 - 1.4e-05 25.1 0.1 0.033 14.2 0.0 2.6 2 0 0 2 2 2 2 NADH(P)-binding KR PF08659.5 EGO54791.1 - 0.0002 21.1 0.0 0.074 12.7 0.0 2.4 2 0 0 2 2 2 2 KR domain UDPG_MGDP_dh_N PF03721.9 EGO54791.1 - 0.0004 19.8 0.1 0.00092 18.6 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.20 EGO54791.1 - 0.0021 17.9 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase DUF2709 PF10915.3 EGO54791.1 - 0.0066 15.4 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2709) DAO PF01266.19 EGO54791.1 - 0.0072 15.2 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase RmlD_sub_bind PF04321.12 EGO54791.1 - 0.011 14.6 0.1 0.097 11.5 0.0 2.2 2 1 0 2 2 2 0 RmlD substrate binding domain Pribosyltran PF00156.22 EGO54791.1 - 0.051 13.3 0.1 5.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosyl transferase domain NAD_binding_2 PF03446.10 EGO54791.1 - 0.082 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 EGO54791.1 - 0.1 12.6 0.1 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glycos_transf_1 PF00534.15 EGO54792.1 - 3.4e-15 55.8 0.0 7.4e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.3 EGO54792.1 - 1.2e-07 31.5 0.0 2.7e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) Glyco_trans_1_4 PF13692.1 EGO54792.1 - 3.3e-05 24.0 0.0 8.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Chorismate_bind PF00425.13 EGO54794.1 - 3.7e-81 272.2 0.0 7e-79 264.7 0.0 3.0 2 1 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EGO54794.1 - 8.8e-32 110.0 0.1 1.7e-27 96.1 0.0 3.3 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region POR PF01558.13 EGO54794.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase p450 PF00067.17 EGO54796.1 - 6.3e-23 81.0 0.0 8.1e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Dynamin_N PF00350.18 EGO54796.1 - 0.053 13.3 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Dynamin family Dala_Dala_lig_C PF07478.8 EGO54797.1 - 2.3e-44 151.2 0.0 2.9e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.16 EGO54797.1 - 5.7e-24 84.6 0.0 1.2e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus ATP-grasp_4 PF13535.1 EGO54797.1 - 7.9e-16 58.3 0.0 1.2e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EGO54797.1 - 1.7e-09 37.3 0.0 3.7e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EGO54797.1 - 7.8e-08 32.3 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EGO54797.1 - 1.7e-05 24.2 0.0 4.4e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EGO54797.1 - 0.0025 17.3 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain UbiA PF01040.13 EGO54798.1 - 3.5e-34 118.2 11.0 4.8e-34 117.7 7.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Lactate_perm PF02652.9 EGO54798.1 - 0.093 11.2 0.4 0.17 10.3 0.3 1.4 1 0 0 1 1 1 0 L-lactate permease FA_desaturase PF00487.19 EGO54798.1 - 0.26 10.6 5.8 2.8 7.3 2.3 2.3 2 0 0 2 2 2 0 Fatty acid desaturase HAD_2 PF13419.1 EGO54799.1 - 1.7e-26 93.5 0.0 2.8e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO54799.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Glyco_transf_90 PF05686.7 EGO54801.1 - 0.00031 19.5 1.2 0.005 15.5 0.2 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 90 Serum_albumin PF00273.15 EGO54802.1 - 0.0015 18.0 1.2 0.0019 17.6 0.8 1.2 1 0 0 1 1 1 1 Serum albumin family Hydrophobin_2 PF06766.6 EGO54802.1 - 1.4 8.6 6.4 3.7 7.2 4.4 1.7 1 1 0 1 1 1 0 Fungal hydrophobin Glyco_hydro_45 PF02015.11 EGO54803.1 - 1.3e-92 309.3 18.7 1.3e-92 309.3 13.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 EGO54803.1 - 2.5e-12 46.2 13.2 2.5e-12 46.2 9.2 3.9 3 0 0 3 3 3 1 Fungal cellulose binding domain RNA_pol_Rpb2_6 PF00562.23 EGO54804.1 - 3.3e-127 424.4 0.1 7.3e-127 423.2 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGO54804.1 - 1.3e-52 177.7 0.0 2e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EGO54804.1 - 6.2e-45 152.9 0.0 1.1e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EGO54804.1 - 1.6e-30 105.2 0.0 4e-30 103.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EGO54804.1 - 2.2e-24 85.1 0.2 6.2e-24 83.7 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EGO54804.1 - 1.6e-22 79.0 0.1 3.4e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 EGO54804.1 - 1.3e-21 76.1 0.4 3.4e-21 74.7 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 MRP-L46 PF11788.3 EGO54806.1 - 0.01 16.4 0.1 0.011 16.3 0.1 1.1 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 RNA_pol_Rpb1_6 PF04992.9 EGO54806.1 - 0.075 12.7 0.7 0.086 12.5 0.5 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 V-ATPase_G PF03179.10 EGO54807.1 - 2e-33 114.8 17.6 2.3e-33 114.6 12.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 EGO54807.1 - 0.0067 16.2 10.3 0.0067 16.2 7.1 2.0 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) YusW PF14039.1 EGO54807.1 - 0.025 14.8 2.9 0.045 14.0 2.0 1.4 1 0 0 1 1 1 0 YusW-like protein DM4_12 PF07841.8 EGO54807.1 - 0.06 13.6 0.2 0.21 11.9 0.0 2.0 1 1 1 2 2 2 0 DM4/DM12 family Asp-B-Hydro_N PF05279.6 EGO54807.1 - 0.31 10.8 10.9 0.35 10.6 7.5 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Vfa1 PF08432.5 EGO54807.1 - 0.37 10.8 10.1 0.42 10.6 7.0 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Borrelia_P83 PF05262.6 EGO54807.1 - 0.39 8.9 13.4 0.44 8.7 9.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Nop25 PF09805.4 EGO54807.1 - 0.5 10.4 17.1 0.68 9.9 11.8 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF3154 PF11351.3 EGO54807.1 - 0.63 9.7 5.2 0.99 9.1 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) ISG65-75 PF11727.3 EGO54807.1 - 0.65 8.9 10.2 0.88 8.5 7.1 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Nucleoporin2 PF04096.9 EGO54807.1 - 0.86 9.4 3.4 0.68 9.7 1.2 1.7 1 1 1 2 2 2 0 Nucleoporin autopeptidase OmpH PF03938.9 EGO54807.1 - 0.96 9.3 14.1 1.1 9.1 9.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3552 PF12072.3 EGO54807.1 - 1.1 8.4 23.8 4.1 6.5 16.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) GA PF01468.12 EGO54807.1 - 1.1 9.4 7.0 1.4 9.0 3.3 2.4 1 1 1 2 2 2 0 GA module DUF2203 PF09969.4 EGO54807.1 - 1.4 9.2 6.6 1.8 8.7 4.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF4407 PF14362.1 EGO54807.1 - 1.9 7.3 10.0 2.2 7.1 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SAPS PF04499.10 EGO54807.1 - 2 6.9 5.7 2 6.9 3.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein APG6 PF04111.7 EGO54807.1 - 2.5 7.0 10.1 2.9 6.8 7.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2870 PF11069.3 EGO54807.1 - 2.9 8.0 7.8 3.3 7.7 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) Atg14 PF10186.4 EGO54807.1 - 3.1 6.6 10.3 3.8 6.3 7.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3987 PF13148.1 EGO54807.1 - 3.7 6.0 12.0 4.2 5.8 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Potyvirid-P3 PF13608.1 EGO54807.1 - 4.5 6.2 8.6 5.9 5.9 6.0 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein HrpE PF06188.7 EGO54807.1 - 5.7 6.6 13.1 0.6 9.8 1.9 2.0 1 1 1 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E CTNNBL PF08216.6 EGO54808.1 - 5.1e-38 128.9 0.6 1.4e-37 127.5 0.4 1.8 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear GP46 PF07409.7 EGO54808.1 - 0.0062 15.8 0.6 0.06 12.6 0.0 2.7 3 1 0 3 3 3 1 Phage protein GP46 Mo25 PF08569.6 EGO54808.1 - 0.016 14.2 0.3 0.11 11.4 0.1 2.2 1 1 1 2 2 2 0 Mo25-like Arm PF00514.18 EGO54808.1 - 0.017 14.9 0.0 1 9.3 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Orthopox_F14 PF06076.7 EGO54808.1 - 6.5 6.8 8.4 1.5 8.9 2.4 2.6 2 1 0 2 2 2 0 Orthopoxvirus F14 protein His_Phos_1 PF00300.17 EGO54809.1 - 1.8e-07 31.3 0.0 2.3e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HET PF06985.6 EGO54810.1 - 9.4e-26 90.6 0.0 1.9e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BAR_2 PF10455.4 EGO54812.1 - 0.0016 17.4 0.1 0.006 15.5 0.1 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Cu-oxidase_3 PF07732.10 EGO54813.1 - 3e-40 136.6 10.3 3.5e-40 136.4 1.5 3.8 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGO54813.1 - 7.5e-40 135.6 10.1 7.2e-38 129.2 0.8 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EGO54813.1 - 3.9e-38 130.8 0.0 1.1e-37 129.3 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase DUF1996 PF09362.5 EGO54816.1 - 5e-06 26.3 0.0 5.2e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RNase_H PF00075.19 EGO54818.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 RNase H Mvb12 PF09452.5 EGO54818.1 - 0.13 12.4 2.7 0.77 9.9 1.1 2.3 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 Pectate_lyase_3 PF12708.2 EGO54821.1 - 1.1e-29 104.1 7.4 1.2e-19 71.3 2.5 2.8 2 1 0 2 2 2 2 Pectate lyase superfamily protein Beta_helix PF13229.1 EGO54821.1 - 0.00017 21.3 2.8 0.00039 20.2 2.0 1.6 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 EGO54821.1 - 0.016 14.3 0.3 0.027 13.6 0.2 1.3 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Glyco_hydro_7 PF00840.15 EGO54822.1 - 3.2e-190 632.1 18.9 3.7e-190 631.8 13.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF3764 PF12594.3 EGO54822.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3764) Toxin_11 PF07473.6 EGO54822.1 - 0.62 9.9 6.4 2.4 8.1 4.4 2.0 1 0 0 1 1 1 0 Spasmodic peptide gm9a RNase_H PF00075.19 EGO54824.1 - 3e-05 24.3 0.0 0.00039 20.7 0.0 2.3 1 1 0 1 1 1 1 RNase H Lig_chan PF00060.21 EGO54825.1 - 3.3 7.3 7.7 1.3 8.7 3.2 1.8 2 0 0 2 2 2 0 Ligand-gated ion channel CorA PF01544.13 EGO54826.1 - 0.00014 21.0 0.0 0.00039 19.5 0.0 1.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Fib_alpha PF08702.5 EGO54826.1 - 0.31 11.1 4.0 0.99 9.5 0.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PS_Dcarbxylase PF02666.10 EGO54828.1 - 2.4e-37 128.2 0.0 3.2e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.3 EGO54828.1 - 1.4e-36 125.1 0.0 2.1e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase RnfC_N PF13375.1 EGO54828.1 - 0.00075 19.1 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 2 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.17 EGO54828.1 - 0.041 13.9 0.1 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M23 Biotin_lipoyl_2 PF13533.1 EGO54828.1 - 0.052 13.2 0.5 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Biotin-lipoyl like Biotin_lipoyl PF00364.17 EGO54828.1 - 0.078 12.6 0.6 2.4 7.8 0.2 2.4 2 0 0 2 2 2 0 Biotin-requiring enzyme RNase_H PF00075.19 EGO54830.1 - 1.4e-08 35.1 0.0 3.2e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 RNase H Dicistro_VP4 PF11492.3 EGO54830.1 - 0.043 13.8 1.6 0.095 12.7 1.1 1.6 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 tRNA-synt_2d PF01409.15 EGO54832.1 - 9.4e-85 283.7 0.0 1.4e-84 283.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EGO54832.1 - 3.4e-06 26.0 0.2 0.00029 19.7 0.0 3.1 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EGO54832.1 - 2.3e-05 24.0 0.0 0.00072 19.1 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) adh_short PF00106.20 EGO54833.1 - 1.2e-18 67.5 7.6 4.7e-17 62.4 5.3 2.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO54833.1 - 5.1e-12 46.0 0.1 2.4e-11 43.8 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO54833.1 - 1.5e-11 44.3 0.3 6.2e-11 42.2 0.1 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EGO54833.1 - 0.0014 17.6 0.0 0.003 16.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGO54833.1 - 0.0041 16.5 0.1 0.015 14.7 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Cys_Met_Meta_PP PF01053.15 EGO54834.1 - 7.2e-25 87.0 0.0 1e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Suppressor_APC PF11414.3 EGO54834.1 - 0.06 13.1 0.1 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Secretin_N_2 PF07655.8 EGO54835.1 - 0.019 15.3 3.4 0.02 15.2 2.4 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain DUF2422 PF10337.4 EGO54835.1 - 0.16 10.7 0.3 0.15 10.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) BLVR PF06375.6 EGO54835.1 - 0.51 10.1 6.9 0.66 9.7 4.8 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) NPR3 PF03666.8 EGO54835.1 - 1.3 7.5 8.2 1.4 7.3 5.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RNase_H PF00075.19 EGO54836.1 - 8.1e-07 29.4 0.0 1.3e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 RNase H MFS_1 PF07690.11 EGO54837.1 - 1.6e-23 82.9 80.4 4.3e-20 71.7 36.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PepSY_TM_1 PF13172.1 EGO54837.1 - 2.2 8.1 10.6 0.062 13.0 1.5 3.0 2 0 0 2 2 2 0 PepSY-associated TM helix Serglycin PF04360.7 EGO54839.1 - 0.0068 16.1 5.6 0.01 15.5 3.9 1.3 1 0 0 1 1 1 1 Serglycin Pex14_N PF04695.8 EGO54840.1 - 2.3 8.2 8.2 2.5 8.1 5.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4509 PF14970.1 EGO54847.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Ribosomal_60s PF00428.14 EGO54847.1 - 0.18 12.1 13.7 0.94 9.9 0.4 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein ATG16 PF08614.6 EGO54847.1 - 3.2 7.5 9.9 0.38 10.5 1.4 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 EGO54847.1 - 5.5 5.9 7.4 0.24 10.3 0.8 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 PTR2 PF00854.16 EGO54848.1 - 2.7e-27 95.5 6.2 5.1e-14 51.8 0.0 2.6 3 0 0 3 3 3 2 POT family MFS_1 PF07690.11 EGO54848.1 - 7.4e-10 38.0 17.8 7.4e-10 38.0 12.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1269 PF06897.7 EGO54848.1 - 0.067 13.2 0.1 7.4 6.6 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) PCMT PF01135.14 EGO54849.1 - 5.5e-55 186.1 0.0 7.4e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EGO54849.1 - 6.9e-06 26.6 0.0 1e-05 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO54849.1 - 7.8e-06 25.9 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO54849.1 - 2.4e-05 23.9 0.0 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGO54849.1 - 0.00021 20.9 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO54849.1 - 0.001 18.8 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EGO54849.1 - 0.036 14.8 0.0 0.062 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EGO54849.1 - 0.046 12.7 0.0 0.064 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 EGO54849.1 - 0.056 13.9 0.0 0.14 12.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EGO54849.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF2370 PF10176.4 EGO54850.1 - 2.4e-87 292.1 0.0 4.7e-87 291.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) PBP1_TM PF14812.1 EGO54850.1 - 0.77 10.1 7.1 0.52 10.6 1.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mito_carr PF00153.22 EGO54851.1 - 1.1e-49 166.0 4.6 9e-23 79.8 0.1 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein Collagen PF01391.13 EGO54854.1 - 9e-05 21.9 16.6 0.00012 21.5 11.5 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Filament_head PF04732.9 EGO54854.1 - 0.087 13.5 8.5 0.14 12.8 5.9 1.3 1 0 0 1 1 1 0 Intermediate filament head (DNA binding) region Peptidase_M35 PF02102.10 EGO54856.1 - 1.4e-87 293.6 13.8 1.7e-87 293.4 9.6 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EGO54856.1 - 8.7e-05 23.0 1.0 0.00015 22.3 0.6 1.5 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Potyvirid-P3 PF13608.1 EGO54856.1 - 0.12 11.4 0.6 0.16 11.0 0.4 1.2 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein DAO PF01266.19 EGO54858.1 - 6.2e-47 160.2 0.1 7.5e-47 159.9 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.21 EGO54858.1 - 5.9e-12 45.0 0.2 1.3e-11 43.8 0.2 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.1 EGO54858.1 - 1.7e-09 37.5 0.3 6.6e-09 35.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EGO54858.1 - 1.4e-06 27.6 2.2 8.3e-06 25.1 1.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO54858.1 - 1.4e-06 27.4 0.6 2.1e-06 26.8 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EGO54858.1 - 1.6e-06 27.4 0.0 2.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EGO54858.1 - 5.2e-06 25.7 0.0 7.7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EGO54858.1 - 1.2e-05 25.6 0.4 3.3e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO54858.1 - 1.4e-05 25.0 0.2 4.2e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGO54858.1 - 0.00014 20.8 0.4 0.0018 17.2 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EGO54858.1 - 0.00019 20.0 0.1 0.00028 19.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EGO54858.1 - 0.00035 20.6 0.0 0.011 15.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO54858.1 - 0.00077 18.4 0.1 0.0025 16.7 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EGO54858.1 - 0.0036 17.0 0.1 0.016 15.0 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EGO54858.1 - 0.0085 15.2 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EGO54858.1 - 0.01 15.4 0.1 0.019 14.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EGO54858.1 - 0.018 14.4 0.4 0.067 12.6 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EGO54858.1 - 0.073 11.6 0.1 0.12 10.9 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_10 PF13460.1 EGO54858.1 - 0.11 12.4 0.4 0.26 11.2 0.2 1.6 1 0 0 1 1 1 0 NADH(P)-binding RTA1 PF04479.8 EGO54859.1 - 7.4e-35 120.4 0.6 9.5e-35 120.1 0.4 1.1 1 0 0 1 1 1 1 RTA1 like protein Abhydrolase_9_N PF15420.1 EGO54859.1 - 0.011 15.5 3.0 0.027 14.2 0.5 2.3 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus UNC-50 PF05216.8 EGO54859.1 - 0.097 11.8 1.8 0.31 10.2 0.0 2.4 2 1 0 3 3 3 0 UNC-50 family DUF962 PF06127.6 EGO54859.1 - 0.12 12.3 0.5 1.2 9.1 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Zn_clus PF00172.13 EGO54860.1 - 7.5e-10 38.5 6.5 1.4e-09 37.7 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGO54860.1 - 0.013 14.0 0.4 0.028 13.0 0.3 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain BTB PF00651.26 EGO54861.1 - 2.1e-13 50.2 0.0 3.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain COG5 PF10392.4 EGO54862.1 - 2.3e-39 134.3 0.7 1.3e-38 131.9 0.0 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF2434 PF10361.4 EGO54863.1 - 1.4e-133 444.5 7.6 1.7e-133 444.2 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) zf-C2H2_4 PF13894.1 EGO54866.1 - 1.1e-06 28.5 11.6 0.00066 19.8 1.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO54866.1 - 2.4e-06 27.5 10.4 0.0074 16.5 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO54866.1 - 3.1e-06 27.1 3.4 3.1e-06 27.1 2.4 3.1 3 0 0 3 3 3 1 Zinc-finger double domain OTT_1508_deam PF14441.1 EGO54868.1 - 2.9e-29 101.7 0.0 5.5e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase zf-H2C2_2 PF13465.1 EGO54869.1 - 6.3e-05 23.0 2.1 0.0011 19.1 0.8 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGO54869.1 - 8.8e-05 22.6 8.3 0.00033 20.8 0.2 3.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type Sina PF03145.11 EGO54869.1 - 0.00063 19.4 0.1 0.00097 18.8 0.1 1.2 1 0 0 1 1 1 1 Seven in absentia protein family zf-C2H2_4 PF13894.1 EGO54869.1 - 0.0029 17.8 3.7 1.6 9.2 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EGO54869.1 - 0.0043 17.1 2.6 0.017 15.3 1.8 2.1 1 0 0 1 1 1 1 C2H2-type zinc-finger domain DUF605 PF04652.11 EGO54869.1 - 4.2 6.6 14.7 4.9 6.4 10.2 1.1 1 0 0 1 1 1 0 Vta1 like CFEM PF05730.6 EGO54870.1 - 5.8e-11 42.0 8.3 1.2e-10 40.9 5.7 1.6 1 0 0 1 1 1 1 CFEM domain FAD_binding_3 PF01494.14 EGO54871.1 - 2.2e-27 96.0 0.0 3.2e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGO54871.1 - 0.14 10.9 1.0 0.6 8.9 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Glyco_hydro_7 PF00840.15 EGO54872.1 - 5.6e-138 459.9 8.4 6.8e-138 459.6 5.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Lipid_bd PF12888.2 EGO54872.1 - 0.022 14.5 0.1 0.053 13.3 0.1 1.6 1 0 0 1 1 1 0 Lipid-binding putative hydrolase EI24 PF07264.6 EGO54877.1 - 0.034 13.5 17.1 0.22 10.9 11.9 2.0 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Fungal_trans PF04082.13 EGO54878.1 - 3.8e-14 52.1 0.3 6.7e-14 51.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO54878.1 - 1.3e-07 31.4 9.1 2.3e-07 30.6 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 EGO54879.1 - 9.2e-42 142.1 0.0 6.7e-27 93.7 0.0 2.8 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EGO54879.1 - 0.0038 17.2 0.0 0.0083 16.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_2 PF03446.10 EGO54879.1 - 0.025 14.4 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.25 EGO54879.1 - 0.041 13.3 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 EGO54879.1 - 0.083 13.3 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.1 EGO54879.1 - 0.084 13.1 0.0 0.21 11.8 0.0 1.8 1 1 0 1 1 1 0 XdhC Rossmann domain Gp_dh_N PF00044.19 EGO54879.1 - 0.11 12.4 0.1 0.26 11.2 0.0 1.6 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DSPc PF00782.15 EGO54880.1 - 1.5e-19 69.8 0.0 1.3e-16 60.3 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGO54880.1 - 0.00066 19.0 0.2 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EGO54880.1 - 0.091 13.0 0.2 7.5 6.7 0.1 2.5 2 0 0 2 2 2 0 Tyrosine phosphatase family Cyt-b5 PF00173.23 EGO54882.1 - 1.2e-13 50.6 0.0 4.1e-10 39.3 0.0 3.5 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain DUF3810 PF12725.2 EGO54882.1 - 1.3 7.8 0.0 2.3 7.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) E1-E2_ATPase PF00122.15 EGO54883.1 - 2.8e-65 219.5 1.6 2.8e-65 219.5 1.1 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGO54883.1 - 1.2e-30 106.4 6.1 1.2e-30 106.4 4.2 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGO54883.1 - 1.7e-30 107.0 0.0 1e-29 104.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO54883.1 - 7e-18 64.3 0.0 1.5e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EGO54883.1 - 5.2e-16 57.8 0.0 1.2e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGO54883.1 - 1e-15 58.4 0.0 5e-15 56.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGO54883.1 - 0.0024 17.5 0.0 0.032 13.8 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SieB PF14163.1 EGO54883.1 - 0.23 11.0 0.4 0.58 9.7 0.0 1.9 2 0 0 2 2 2 0 Superinfection exclusion protein B MFS_1 PF07690.11 EGO54884.1 - 1.2e-25 90.0 61.5 2.5e-20 72.5 28.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BTB PF00651.26 EGO54885.1 - 1.1e-25 89.7 0.0 1.6e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Cu-oxidase_2 PF07731.9 EGO54887.1 - 2.2e-26 92.0 1.8 4.3e-24 84.5 0.8 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGO54887.1 - 1e-21 76.8 0.6 3.7e-21 75.0 0.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EGO54887.1 - 3.4e-05 23.7 0.0 0.00056 19.8 0.0 2.9 3 1 0 3 3 3 1 Multicopper oxidase 2C_adapt PF08793.5 EGO54887.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 2-cysteine adaptor domain MSP1_C PF07462.6 EGO54887.1 - 1.2 7.4 4.3 1.8 6.8 2.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Glyco_transf_20 PF00982.16 EGO54888.1 - 1.1e-147 492.3 0.0 1.5e-147 491.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EGO54888.1 - 5.3e-77 257.9 0.0 9.4e-77 257.0 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase GFA PF04828.9 EGO54889.1 - 2.2e-10 40.3 0.7 2.2e-10 40.3 0.5 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_2 PF00891.13 EGO54890.1 - 5.5e-25 87.9 0.0 1.3e-24 86.7 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_18 PF12847.2 EGO54890.1 - 0.044 14.3 0.0 0.42 11.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain 2OG-FeII_Oxy PF03171.15 EGO54891.1 - 1.2e-24 86.5 0.0 4.1e-24 84.7 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGO54891.1 - 1.7e-22 80.1 0.0 3.2e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DHDPS PF00701.17 EGO54892.1 - 8e-27 93.5 0.0 1.1e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family RNase_T PF00929.19 EGO54893.1 - 3.5e-13 50.1 0.1 2.3e-09 37.7 0.0 2.4 1 1 0 2 2 2 2 Exonuclease zf-C2H2_4 PF13894.1 EGO54894.1 - 1.4e-07 31.3 3.3 0.011 16.0 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO54894.1 - 0.0042 17.3 5.6 0.48 10.8 0.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-TRAF PF02176.13 EGO54894.1 - 0.13 12.6 1.2 6.2 7.2 0.1 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger Gon7 PF08738.5 EGO54894.1 - 0.23 11.4 3.4 0.19 11.7 0.6 2.2 2 0 0 2 2 2 0 Gon7 family PgaD PF13994.1 EGO54895.1 - 0.27 10.7 0.1 0.27 10.7 0.1 2.0 2 0 0 2 2 2 0 PgaD-like protein INCENP_ARK-bind PF03941.10 EGO54895.1 - 0.69 9.8 4.6 1.8 8.4 2.5 2.2 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region F-box PF00646.28 EGO54896.1 - 2.6e-05 23.7 2.3 0.00039 20.0 0.2 3.0 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EGO54896.1 - 0.014 15.0 0.9 0.046 13.4 0.2 2.0 2 0 0 2 2 2 0 F-box-like F-box-like_2 PF13013.1 EGO54896.1 - 0.085 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain UNC119_bdg PF15435.1 EGO54897.1 - 0.15 11.3 0.1 1.1 8.5 0.0 1.9 2 0 0 2 2 2 0 UNC119-binding protein C5orf30 homologue Crystall_3 PF08964.5 EGO54898.1 - 0.013 15.2 0.1 0.023 14.4 0.0 1.5 1 1 0 1 1 1 0 Beta/Gamma crystallin Crystall_3 PF08964.5 EGO54899.1 - 0.088 12.5 0.2 2.5 7.9 0.0 1.9 1 1 1 2 2 2 0 Beta/Gamma crystallin ABC_membrane PF00664.18 EGO54900.1 - 1.1e-37 129.9 12.3 1.4e-37 129.6 8.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGO54900.1 - 7.7e-34 116.9 0.0 3.1e-33 114.9 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EGO54900.1 - 9.8e-08 32.2 0.1 0.0037 17.2 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EGO54900.1 - 1.3e-05 25.3 0.0 6.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EGO54900.1 - 2.2e-05 24.3 0.0 0.00017 21.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EGO54900.1 - 3.3e-05 23.2 0.0 0.016 14.4 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EGO54900.1 - 0.00014 22.6 0.0 0.00043 21.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EGO54900.1 - 0.00025 21.2 0.0 0.0016 18.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGO54900.1 - 0.0027 16.9 0.0 0.0059 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGO54900.1 - 0.003 17.0 0.0 0.0084 15.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 EGO54900.1 - 0.0053 16.9 0.0 0.056 13.6 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EGO54900.1 - 0.0061 15.6 0.0 0.036 13.1 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 EGO54900.1 - 0.0096 15.3 0.0 0.027 13.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 EGO54900.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 EGO54900.1 - 0.024 14.5 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGO54900.1 - 0.024 14.9 0.0 0.082 13.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.18 EGO54900.1 - 0.025 14.5 0.0 0.074 13.0 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EGO54900.1 - 0.036 13.5 0.0 0.084 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 EGO54900.1 - 0.043 13.5 0.0 0.13 11.9 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 EGO54900.1 - 0.044 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EGO54900.1 - 0.051 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EGO54900.1 - 0.059 13.8 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_5 PF07728.9 EGO54900.1 - 0.064 12.9 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EGO54900.1 - 0.071 13.0 0.5 0.58 10.1 0.3 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 EGO54900.1 - 0.12 12.0 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.10 EGO54900.1 - 0.12 10.9 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Kinesin PF00225.18 EGO54901.1 - 1.8e-33 115.7 0.2 2.9e-33 114.9 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain HHH_3 PF12836.2 EGO54901.1 - 0.006 16.5 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.18 EGO54901.1 - 0.033 13.8 0.2 1.7 8.4 0.1 2.9 3 0 0 3 3 3 0 Helix-hairpin-helix motif MIT PF04212.13 EGO54901.1 - 0.034 14.0 0.1 0.14 12.0 0.1 2.1 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain AIM24 PF01987.12 EGO54902.1 - 7.8e-58 195.4 0.0 1e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 HhH-GPD PF00730.20 EGO54903.1 - 1.1e-06 28.8 0.2 2.6e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EGO54903.1 - 0.0037 16.9 0.0 0.011 15.3 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 EGO54903.1 - 0.029 14.2 0.0 8.1 6.4 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF3439 PF11921.3 EGO54903.1 - 0.077 12.7 13.1 2 8.1 0.9 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) CsgF PF10614.4 EGO54903.1 - 1.7 8.6 6.9 5.2 7.0 4.8 1.8 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein DUF853 PF05872.7 EGO54903.1 - 3.7 5.7 9.4 0.35 9.1 2.7 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) TATR PF03430.8 EGO54903.1 - 4.1 5.9 7.7 0.19 10.3 0.4 2.1 2 0 0 2 2 2 0 Trans-activating transcriptional regulator EndIII_4Fe-2S PF10576.4 EGO54903.1 - 6 7.2 9.9 0.33 11.2 1.4 2.5 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III NUDIX_4 PF14815.1 EGO54904.1 - 9.7e-20 70.0 0.0 2e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.20 EGO54904.1 - 3.9e-13 49.6 0.0 7.5e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX PF00293.23 EGO54904.1 - 8.1e-05 22.2 0.9 0.00022 20.9 0.1 2.1 3 0 0 3 3 3 1 NUDIX domain Mucin PF01456.12 EGO54904.1 - 1.5 8.6 22.1 3.6 7.3 15.3 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein EndIII_4Fe-2S PF10576.4 EGO54904.1 - 1.9 8.7 10.5 0.085 13.0 2.5 2.5 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III zf-H2C2_5 PF13909.1 EGO54906.1 - 0.0049 17.0 3.5 0.009 16.1 2.4 1.5 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EGO54906.1 - 0.028 14.5 3.4 0.049 13.7 2.4 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EGO54906.1 - 0.43 11.0 2.5 0.8 10.1 1.8 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO54906.1 - 0.71 10.3 3.7 1.3 9.5 2.6 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2434 PF10361.4 EGO54907.1 - 0.071 12.1 0.1 0.075 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) Oxidored_q4 PF00507.14 EGO54907.1 - 0.5 10.2 4.2 0.8 9.5 2.3 1.7 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 zf-C2H2_4 PF13894.1 EGO54908.1 - 0.0044 17.2 8.4 0.026 14.8 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO54908.1 - 0.0062 16.8 9.8 0.021 15.1 0.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EGO54908.1 - 0.22 11.6 2.0 0.66 10.1 0.8 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF4540 PF15073.1 EGO54909.1 - 0.091 13.3 4.7 0.12 12.9 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4540) zf-C2H2_4 PF13894.1 EGO54910.1 - 1e-09 37.9 6.0 2.1e-07 30.8 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO54910.1 - 1.7e-07 31.1 6.6 0.00013 22.1 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 EGO54910.1 - 0.00039 20.4 2.2 0.97 9.6 0.0 2.9 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EGO54910.1 - 0.00051 20.1 2.3 0.0033 17.5 0.9 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGO54910.1 - 0.00094 19.3 0.9 1.5 9.1 1.0 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-BED PF02892.10 EGO54910.1 - 0.0023 17.6 4.0 0.99 9.2 1.0 2.7 3 0 0 3 3 3 2 BED zinc finger DUF3449 PF11931.3 EGO54910.1 - 0.024 14.1 0.5 0.024 14.1 0.3 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) zf-C2H2_2 PF12756.2 EGO54910.1 - 0.036 14.1 0.6 0.58 10.3 0.2 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 EGO54910.1 - 0.046 13.3 1.2 0.094 12.4 0.2 2.0 2 0 0 2 2 2 0 DBF zinc finger zf-C2H2_6 PF13912.1 EGO54910.1 - 0.048 13.5 0.4 14 5.7 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGO54910.1 - 0.1 12.9 12.4 5.4 7.4 0.0 3.9 3 1 0 3 3 3 0 Zinc-finger double domain RNase_H PF00075.19 EGO54912.1 - 0.0003 21.1 4.5 0.0031 17.8 0.0 3.3 2 1 0 3 3 3 1 RNase H MIP-T3 PF10243.4 EGO54912.1 - 0.0016 16.9 16.6 0.0016 16.9 11.5 1.4 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Trypsin_2 PF13365.1 EGO54915.1 - 8.7e-07 28.9 0.1 3.4e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.21 EGO54915.1 - 2.1e-05 24.2 0.0 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin NUDIX PF00293.23 EGO54917.1 - 8.1e-07 28.7 0.1 1.6e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain DUF2650 PF10853.3 EGO54917.1 - 0.11 11.9 0.2 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) MHYT PF03707.11 EGO54918.1 - 7.7e-06 25.9 23.9 0.00017 21.6 2.5 3.5 3 1 0 3 3 3 2 Bacterial signalling protein N terminal repeat ABC2_membrane_3 PF12698.2 EGO54918.1 - 1.4 7.8 8.4 3.1 6.7 5.8 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein FSH1 PF03959.8 EGO54919.1 - 2e-22 79.6 0.0 6.4e-22 78.0 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PE-PPE PF08237.6 EGO54919.1 - 0.027 13.8 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 PE-PPE domain ketoacyl-synt PF00109.21 EGO54921.1 - 6.4e-77 258.4 0.0 1.4e-76 257.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGO54921.1 - 2.1e-61 208.0 0.0 3.4e-61 207.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EGO54921.1 - 1.2e-59 201.0 0.1 3.2e-59 199.6 0.1 1.8 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGO54921.1 - 3.6e-48 163.6 0.2 1.4e-47 161.7 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EGO54921.1 - 5.8e-38 130.7 1.4 3.7e-21 75.5 0.1 2.5 2 0 0 2 2 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EGO54921.1 - 1e-31 109.2 0.0 4.7e-31 107.1 0.0 2.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EGO54921.1 - 2.9e-11 43.0 0.6 1.8e-09 37.2 0.1 3.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EGO54921.1 - 1.1e-09 38.3 0.6 3.1e-09 36.9 0.4 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGO54921.1 - 9.4e-06 24.7 0.0 2.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.16 EGO54921.1 - 6.3e-05 22.5 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGO54921.1 - 0.068 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_N PF08240.7 EGO54921.1 - 0.088 12.5 0.7 0.21 11.3 0.5 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Shikimate_DH PF01488.15 EGO54921.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fer4 PF00037.22 EGO54923.1 - 3.7e-14 51.6 16.4 5.1e-08 32.1 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EGO54923.1 - 3.5e-12 46.4 11.0 5.8e-12 45.7 7.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EGO54923.1 - 4.8e-10 40.0 8.3 0.00021 21.9 0.3 2.5 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 EGO54923.1 - 7.9e-10 38.3 22.2 2.7e-08 33.4 8.5 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGO54923.1 - 8.1e-10 38.8 11.0 1.6e-09 37.8 7.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EGO54923.1 - 1.6e-09 37.4 32.5 5.4e-06 26.1 8.8 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.1 EGO54923.1 - 8.7e-09 35.2 31.4 7.7e-06 25.8 8.4 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EGO54923.1 - 3.2e-08 33.0 15.0 0.00042 20.0 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EGO54923.1 - 9.9e-08 31.5 17.0 0.0005 19.8 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EGO54923.1 - 3.9e-06 26.7 13.1 0.00043 20.3 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EGO54923.1 - 4.5e-06 26.9 10.3 0.00056 20.2 8.0 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EGO54923.1 - 1.2e-05 25.6 9.5 0.0034 17.7 0.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EGO54923.1 - 0.0064 16.8 14.5 0.31 11.4 2.9 2.8 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EGO54923.1 - 0.017 15.6 13.1 0.31 11.6 1.2 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 EGO54923.1 - 0.035 14.6 17.7 0.15 12.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EGO54923.1 - 0.12 12.5 4.9 0.28 11.3 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain PP-binding PF00550.20 EGO54924.1 - 2.3e-12 47.0 0.3 2.9e-12 46.6 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EGO54924.1 - 1.7e-05 24.7 0.3 2.2e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 Acyl-carrier AFOR_C PF01314.13 EGO54924.1 - 0.14 10.7 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 zf-CCCH PF00642.19 EGO54925.1 - 1.9e-10 40.1 8.1 2.7e-05 23.7 1.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGO54925.1 - 0.032 14.2 16.5 0.25 11.4 3.4 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type p450 PF00067.17 EGO54926.1 - 5.8e-49 166.8 0.0 7.3e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hemerythrin PF01814.18 EGO54927.1 - 2.8e-15 56.6 1.9 4e-15 56.1 1.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF1031 PF06275.6 EGO54927.1 - 0.026 14.5 0.1 0.07 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) DUF596 PF04591.7 EGO54927.1 - 0.041 13.7 0.0 5.2 7.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF596 DUF3445 PF11927.3 EGO54928.1 - 2e-78 263.2 0.2 3.3e-78 262.5 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3445) Fungal_trans_2 PF11951.3 EGO54930.1 - 0.00054 18.6 0.0 0.00097 17.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 EGO54932.1 - 4.6e-52 177.0 0.0 5.8e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2196 PF09962.4 EGO54933.1 - 9.8e-23 79.7 2.9 1.5e-22 79.0 2.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) zf-Di19 PF05605.7 EGO54933.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF3439 PF11921.3 EGO54933.1 - 0.16 11.7 4.1 0.27 10.9 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF423 PF04241.10 EGO54934.1 - 2e-22 78.9 2.0 3.8e-22 78.0 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Bax1-I PF01027.15 EGO54934.1 - 0.0094 15.5 6.3 0.01 15.4 4.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Trep_Strep PF09605.5 EGO54934.1 - 0.053 13.2 0.6 0.075 12.6 0.4 1.2 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Oxidored_q3 PF00499.15 EGO54934.1 - 0.21 11.3 1.5 0.29 10.8 0.8 1.4 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF1469 PF07332.6 EGO54934.1 - 5.4 6.7 9.2 6 6.6 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1469) NmrA PF05368.8 EGO54935.1 - 1.2e-17 64.0 0.0 1.6e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO54935.1 - 3.2e-08 33.7 0.0 5.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGO54935.1 - 0.0016 17.4 0.0 0.0036 16.2 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 EGO54935.1 - 0.068 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AMP-binding PF00501.23 EGO54936.1 - 1e-30 106.4 0.0 8.1e-30 103.5 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EGO54936.1 - 7.5e-29 100.3 0.0 1.3e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EGO54936.1 - 4.3e-08 32.8 0.0 8.3e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EGO54936.1 - 1.1e-05 25.6 0.0 2.9e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EGO54936.1 - 0.0036 16.2 0.0 0.019 13.9 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 EGO54936.1 - 0.026 14.4 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EGO54936.1 - 0.074 11.9 0.0 0.26 10.1 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sugar_tr PF00083.19 EGO54937.1 - 8.5e-62 209.1 19.8 9.8e-62 208.9 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO54937.1 - 3.4e-20 72.0 29.5 3.4e-20 72.0 20.5 2.0 1 1 2 3 3 3 1 Major Facilitator Superfamily Glyco_hydro_10 PF00331.15 EGO54939.1 - 9.6e-102 340.2 0.6 1.2e-101 339.9 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EGO54939.1 - 4.5e-14 51.7 11.2 1.3e-13 50.3 7.7 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EGO54939.1 - 0.083 12.9 2.0 0.17 11.9 1.4 1.5 1 0 0 1 1 1 0 Toxin 7 Acetyltransf_3 PF13302.1 EGO54940.1 - 8.7e-18 64.8 0.0 1.1e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO54940.1 - 9.7e-05 22.2 0.0 0.00013 21.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO54940.1 - 0.13 12.0 0.1 0.74 9.6 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein Peptidase_M28 PF04389.12 EGO54942.1 - 1.3e-36 125.9 0.1 2.2e-36 125.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EGO54942.1 - 2.5e-07 30.4 0.0 3.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EGO54942.1 - 0.0077 15.4 0.3 0.22 10.7 0.0 2.4 2 0 0 2 2 2 1 Nicastrin Peptidase_M42 PF05343.9 EGO54942.1 - 0.04 12.6 0.0 0.49 9.1 0.0 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase TOH_N PF12549.3 EGO54943.1 - 0.15 11.6 3.0 0.27 10.8 0.1 2.5 2 0 0 2 2 2 0 Tyrosine hydroxylase N terminal YolD PF08863.5 EGO54944.1 - 0.0082 15.9 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 YolD-like protein CK2S PF15011.1 EGO54944.1 - 0.046 13.5 0.9 0.084 12.6 0.6 1.5 1 1 0 1 1 1 0 Casein Kinase 2 substrate OPT PF03169.10 EGO54945.1 - 2.8e-173 577.7 45.1 3.2e-173 577.5 31.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1989 PF09347.5 EGO54946.1 - 1.4e-54 183.9 0.0 1.8e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) RPE65 PF03055.10 EGO54947.1 - 1.1e-119 400.1 0.0 1.3e-119 400.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Abhydrolase_3 PF07859.8 EGO54948.1 - 4e-32 111.5 0.0 5.7e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EGO54948.1 - 0.18 10.4 0.1 0.28 9.8 0.1 1.2 1 0 0 1 1 1 0 Carboxylesterase family Aminotran_3 PF00202.16 EGO54949.1 - 1.2e-52 178.9 0.0 1.5e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III TSP9 PF11493.3 EGO54950.1 - 0.12 12.8 0.8 1.1 9.8 0.1 2.4 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 WD40 PF00400.27 EGO54951.1 - 3.4e-13 48.9 11.6 0.0032 17.2 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EGO54951.1 - 0.12 10.5 0.0 0.18 9.8 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 GRAM PF02893.15 EGO54952.1 - 1.5e-25 88.4 0.2 2.7e-14 52.4 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 EGO54952.1 - 2e-24 85.9 0.0 4.1e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 EGO54952.1 - 4.9e-17 62.0 0.1 3.9e-16 59.1 0.1 2.5 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 EGO54952.1 - 4.4e-06 26.9 0.7 4.4e-06 26.9 0.5 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EGO54952.1 - 4.6e-06 26.6 0.2 1.2e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.13 EGO54952.1 - 0.00016 20.3 0.0 0.00038 19.1 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.1 EGO54952.1 - 0.00033 20.4 0.0 0.00071 19.4 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 EGO54952.1 - 0.0024 17.9 0.1 0.01 15.8 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 EGO54952.1 - 0.0037 17.4 0.1 0.012 15.7 0.1 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.5 EGO54952.1 - 0.29 11.0 0.0 0.68 9.8 0.0 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region NIF PF03031.13 EGO54953.1 - 1.2e-30 106.2 0.0 2.5e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EGO54953.1 - 3.2e-09 36.4 0.1 3.1e-08 33.3 0.0 2.3 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EGO54953.1 - 2.2e-07 30.8 0.0 5.4e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain GRIM-19 PF06212.7 EGO54954.1 - 9.1e-22 77.1 0.0 1.4e-21 76.5 0.0 1.2 1 1 0 1 1 1 1 GRIM-19 protein Helicase_C_2 PF13307.1 EGO54956.1 - 3.5e-64 215.7 0.4 1.1e-63 214.1 0.0 2.1 3 0 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.10 EGO54956.1 - 4.7e-48 162.8 0.0 8.6e-48 162.0 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 OmpH PF03938.9 EGO54956.1 - 1.3 8.9 5.5 0.71 9.8 1.6 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Pkinase PF00069.20 EGO54957.1 - 1.9e-41 141.9 0.0 1.2e-37 129.5 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO54957.1 - 2.6e-13 49.6 0.0 2.5e-07 30.0 0.0 3.7 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.18 EGO54957.1 - 0.00053 19.7 0.0 0.1 12.2 0.0 3.1 2 2 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGO54957.1 - 0.012 14.5 0.0 0.3 10.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like CDC45 PF02724.9 EGO54957.1 - 0.32 8.9 20.0 0.53 8.2 13.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Cnd1_N PF12922.2 EGO54958.1 - 1.4e-55 187.5 3.2 7e-55 185.2 0.1 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 EGO54958.1 - 3.6e-54 183.3 1.0 1.1e-50 171.9 0.0 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EGO54958.1 - 4.8e-11 41.7 5.8 0.043 13.9 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EGO54958.1 - 1.3e-10 41.3 8.1 1.6e-05 25.1 0.1 6.1 6 2 1 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 EGO54958.1 - 1.6e-06 28.4 2.7 0.078 13.4 0.1 5.5 5 0 0 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.15 EGO54958.1 - 3.3e-05 22.4 3.1 0.0057 15.0 0.2 3.2 3 0 0 3 3 3 2 Adaptin N terminal region DUF2435 PF10363.4 EGO54958.1 - 0.00012 21.8 0.0 1.2 9.1 0.0 4.4 4 1 1 5 5 5 1 Protein of unknown function (DUF2435) Cnd3 PF12719.2 EGO54958.1 - 0.0016 17.4 2.3 0.009 15.0 0.1 3.0 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.2 EGO54958.1 - 0.02 14.8 0.0 2.5 8.1 0.0 3.6 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion TMA7 PF09072.5 EGO54958.1 - 7.1 7.1 9.7 3.4 8.1 1.0 3.4 3 0 0 3 3 3 0 Translation machinery associated TMA7 EphA2_TM PF14575.1 EGO54961.1 - 0.29 11.5 0.0 0.29 11.5 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FtsX PF02687.16 EGO54961.1 - 0.7 9.6 7.0 1 9.1 4.9 1.1 1 0 0 1 1 1 0 FtsX-like permease family DUF3431 PF11913.3 EGO54962.1 - 2e-90 302.1 0.0 2.4e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Podoplanin PF05808.6 EGO54963.1 - 0.002 17.6 1.0 0.0033 16.9 0.7 1.2 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.1 EGO54963.1 - 0.035 13.8 0.1 0.087 12.5 0.1 1.6 1 1 0 1 1 1 0 TMEM154 protein family Rax2 PF12768.2 EGO54963.1 - 0.055 12.6 0.0 0.1 11.8 0.0 1.4 1 1 0 1 1 1 0 Cortical protein marker for cell polarity EphA2_TM PF14575.1 EGO54963.1 - 0.1 12.9 0.0 0.27 11.6 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 EGO54963.1 - 0.21 11.2 0.3 0.33 10.5 0.2 1.4 1 1 0 1 1 1 0 Rifin/stevor family Alpha_GJ PF03229.8 EGO54963.1 - 5.9 7.2 13.8 16 5.8 9.3 1.9 1 1 0 1 1 1 0 Alphavirus glycoprotein J DUF4585 PF15232.1 EGO54964.1 - 0.11 12.3 0.8 0.19 11.6 0.3 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4585) Evr1_Alr PF04777.8 EGO54967.1 - 3.7e-26 90.8 0.0 5.2e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Toxin-deaminase PF14424.1 EGO54967.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Proteasome PF00227.21 EGO54968.1 - 1.5e-48 164.6 0.2 1.7e-48 164.4 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.6 EGO54969.1 - 2e-35 122.4 10.4 6.6e-23 81.7 0.0 3.3 4 0 0 4 4 4 2 Cyclin BUD22 PF09073.5 EGO54969.1 - 0.001 18.2 4.2 0.001 18.2 2.9 3.2 4 0 0 4 4 4 1 BUD22 Peptidase_S49_N PF08496.5 EGO54969.1 - 5.4 6.8 7.2 3.7 7.3 0.0 3.0 3 0 0 3 3 3 0 Peptidase family S49 N-terminal U79_P34 PF03064.11 EGO54971.1 - 5 6.5 10.0 4.6 6.6 6.9 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Sugar_tr PF00083.19 EGO54972.1 - 5.4e-89 298.8 26.1 6.8e-89 298.5 18.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO54972.1 - 4.3e-15 55.2 47.7 1.3e-08 33.9 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.23 EGO54972.1 - 0.098 11.0 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme DUF3445 PF11927.3 EGO54973.1 - 7.3e-59 199.1 0.0 8.5e-59 198.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) ADH_zinc_N PF00107.21 EGO54974.1 - 3.6e-29 100.9 0.2 6e-29 100.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO54974.1 - 1.5e-17 64.6 0.1 5.1e-17 62.9 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO54974.1 - 1.2e-10 41.1 0.0 3.1e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EGO54974.1 - 8.8e-05 22.4 0.0 0.00024 21.0 0.0 1.8 1 1 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 EGO54974.1 - 0.032 13.8 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Hexapep PF00132.19 EGO54976.1 - 9e-15 53.4 5.0 1.7e-09 36.7 2.1 3.4 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGO54976.1 - 9.1e-13 47.5 9.0 1.8e-10 40.1 2.3 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EGO54976.1 - 1.6e-10 40.8 0.2 3.2e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase HET PF06985.6 EGO54977.1 - 1.1e-20 74.2 0.0 2.5e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_31 PF01055.21 EGO54978.1 - 2.2e-165 550.8 1.6 2.7e-165 550.5 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGO54978.1 - 4.3e-09 36.0 0.5 1.9e-08 34.0 0.3 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like Cu-oxidase_2 PF07731.9 EGO54981.1 - 1.4e-36 125.0 4.2 1.1e-34 118.9 0.3 3.3 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EGO54981.1 - 5.3e-32 110.9 0.0 9.2e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGO54981.1 - 2.5e-26 91.7 0.1 2.5e-26 91.7 0.1 3.3 4 1 0 4 4 4 1 Multicopper oxidase adh_short PF00106.20 EGO54982.1 - 3.5e-14 53.0 0.0 1.3e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGO54982.1 - 4.7e-07 29.6 0.0 1.1e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EGO54982.1 - 0.072 12.5 0.0 0.16 11.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2797 PF10977.3 EGO54984.1 - 0.051 13.1 1.9 0.076 12.6 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) NmrA PF05368.8 EGO54986.1 - 7.2e-14 51.6 0.0 1.3e-13 50.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO54986.1 - 5e-13 49.4 0.0 1.5e-12 47.9 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO54986.1 - 0.074 12.4 0.0 0.66 9.3 0.0 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF605 PF04652.11 EGO54986.1 - 6 6.1 9.1 7.7 5.7 6.3 1.1 1 0 0 1 1 1 0 Vta1 like Tcp11 PF05794.8 EGO54987.1 - 6.5e-43 147.0 0.9 2.1e-42 145.4 0.0 1.9 2 0 0 2 2 2 1 T-complex protein 11 V_ATPase_I PF01496.14 EGO54987.1 - 3.8 5.2 5.0 5.5 4.7 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prenyltrans_2 PF13249.1 EGO54989.1 - 1.2e-06 28.9 3.4 0.049 14.0 0.1 4.8 4 1 2 6 6 6 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGO54989.1 - 0.011 15.6 0.0 1.4 8.9 0.0 3.7 3 1 1 4 4 4 0 Prenyltransferase-like Prenyltrans PF00432.16 EGO54989.1 - 0.029 13.9 0.2 0.32 10.5 0.0 2.9 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat FAD_binding_4 PF01565.18 EGO54990.1 - 1.3e-27 95.9 0.2 2.4e-27 95.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.17 EGO54991.1 - 6.6e-37 127.1 1.0 1.9e-36 125.5 0.7 1.6 1 1 0 1 1 1 1 Cytochrome P450 GP46 PF07409.7 EGO54991.1 - 0.058 12.7 0.2 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Phage protein GP46 Mucin PF01456.12 EGO54992.1 - 0.0055 16.4 11.2 0.0075 16.0 7.8 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein TMEM154 PF15102.1 EGO54992.1 - 1.1 8.8 6.2 1.8 8.2 4.3 1.2 1 0 0 1 1 1 0 TMEM154 protein family Lgl_C PF08596.5 EGO54993.1 - 7.7e-131 436.1 0.0 1.3e-130 435.3 0.0 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EGO54993.1 - 1.5e-05 24.6 4.4 0.0037 17.1 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGO54993.1 - 0.049 12.3 0.0 16 4.1 0.0 3.6 2 1 0 3 3 3 0 Nup133 N terminal like Nup160 PF11715.3 EGO54993.1 - 0.12 10.5 0.0 11 4.0 0.0 2.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Baculo_PEP_C PF04513.7 EGO54994.1 - 0.79 9.5 2.7 1.5e+02 2.2 0.1 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Piwi PF02171.12 EGO54995.1 - 1.8e-81 273.4 0.8 2.5e-81 272.9 0.5 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EGO54995.1 - 1.1e-17 63.1 0.0 3.3e-17 61.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EGO54995.1 - 5.2e-10 38.7 0.1 1.1e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 PAZ domain Suf PF05843.9 EGO54996.1 - 2e-90 303.3 1.2 1.4e-85 287.4 0.0 3.8 4 2 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EGO54996.1 - 3.9e-06 27.0 0.3 0.001 19.4 0.2 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO54996.1 - 5e-05 23.5 0.0 0.00027 21.2 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO54996.1 - 5.3e-05 23.7 2.2 0.00025 21.6 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat HAT PF02184.11 EGO54996.1 - 0.00062 19.4 0.0 0.031 14.0 0.0 3.1 3 0 0 3 3 3 1 HAT (Half-A-TPR) repeat Globin PF00042.17 EGO54996.1 - 0.044 14.1 0.5 0.29 11.4 0.0 2.5 2 1 0 2 2 2 0 Globin NRDE-2 PF08424.5 EGO54996.1 - 0.12 11.2 2.9 0.62 8.8 0.0 3.2 3 1 2 5 5 5 0 NRDE-2, necessary for RNA interference ASF1_hist_chap PF04729.8 EGO54997.1 - 3.6e-66 221.5 0.1 4.9e-66 221.1 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nrap PF03813.9 EGO54998.1 - 0 1080.2 0.0 1.1e-184 615.7 0.0 2.0 1 1 1 2 2 2 2 Nrap protein Hpt PF01627.18 EGO54998.1 - 0.034 14.1 0.8 0.1 12.6 0.5 1.8 1 0 0 1 1 1 0 Hpt domain TPR_11 PF13414.1 EGO54999.1 - 2.2e-43 145.7 34.9 5e-06 26.0 0.0 12.3 12 0 0 12 12 12 9 TPR repeat TPR_16 PF13432.1 EGO54999.1 - 9.3e-33 112.1 40.8 1.1e-06 29.1 0.0 13.4 12 4 2 14 14 14 7 Tetratricopeptide repeat TPR_19 PF14559.1 EGO54999.1 - 4.8e-31 106.8 29.7 9.5e-06 25.8 0.1 13.1 12 1 2 14 14 14 6 Tetratricopeptide repeat TPR_2 PF07719.12 EGO54999.1 - 7.3e-31 103.5 42.3 6e-05 22.6 0.0 16.9 17 0 0 17 17 17 9 Tetratricopeptide repeat TPR_14 PF13428.1 EGO54999.1 - 8.2e-29 97.4 37.7 0.00014 22.1 0.1 16.3 13 4 5 18 18 18 8 Tetratricopeptide repeat TPR_1 PF00515.23 EGO54999.1 - 2.1e-27 93.5 24.3 3.5e-06 26.3 0.0 13.4 14 0 0 14 14 13 8 Tetratricopeptide repeat TPR_17 PF13431.1 EGO54999.1 - 1.2e-26 90.6 14.2 0.0082 16.2 0.0 14.0 16 0 0 16 16 12 6 Tetratricopeptide repeat TPR_8 PF13181.1 EGO54999.1 - 4.7e-21 72.9 18.6 0.004 16.8 0.0 11.8 12 1 1 13 13 11 6 Tetratricopeptide repeat TPR_12 PF13424.1 EGO54999.1 - 5.7e-20 71.0 41.9 0.00018 21.3 0.0 12.3 8 3 4 13 13 13 7 Tetratricopeptide repeat TPR_6 PF13174.1 EGO54999.1 - 1.6e-12 46.9 20.4 0.054 13.9 0.0 13.8 17 1 0 17 17 13 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGO54999.1 - 4.4e-11 41.7 25.7 0.00099 18.7 0.0 13.3 15 0 0 15 15 15 2 Tetratricopeptide repeat Apc3 PF12895.2 EGO54999.1 - 4.1e-08 33.2 23.8 0.3 11.2 0.0 7.9 8 0 0 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EGO54999.1 - 1.6e-07 31.0 12.6 0.0004 20.1 0.1 6.2 6 1 0 6 6 5 1 Tetratricopeptide repeat ChAPs PF09295.5 EGO54999.1 - 0.00049 18.9 1.1 0.85 8.3 0.0 4.2 5 0 0 5 5 5 1 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.1 EGO54999.1 - 0.02 14.7 0.1 4.9 7.0 0.0 4.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 EGO54999.1 - 0.046 14.1 34.0 2.9 8.5 0.4 9.5 10 0 0 10 10 8 0 Tetratricopeptide repeat DUF1767 PF08585.7 EGO55000.1 - 0.0002 21.5 0.0 0.00081 19.6 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1767) Polysacc_synt_4 PF04669.8 EGO55002.1 - 4.7e-25 88.0 0.3 2.9e-24 85.5 0.2 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis ABC_membrane PF00664.18 EGO55003.1 - 2.9e-63 213.8 28.0 4.9e-36 124.5 4.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGO55003.1 - 4.2e-58 195.5 0.0 1.7e-27 96.3 0.0 3.0 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EGO55003.1 - 8.7e-15 55.4 0.0 0.013 15.5 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EGO55003.1 - 2.7e-13 49.6 0.1 0.00025 20.3 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGO55003.1 - 3e-07 29.8 1.2 0.011 15.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EGO55003.1 - 8.7e-07 28.5 0.2 0.026 13.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EGO55003.1 - 1e-06 29.5 0.3 0.09 13.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGO55003.1 - 2.1e-06 27.8 0.2 0.09 12.7 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EGO55003.1 - 2.1e-06 26.9 0.0 0.046 12.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGO55003.1 - 2.7e-06 27.5 0.1 0.24 11.5 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EGO55003.1 - 0.00027 21.3 0.2 1.1 9.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGO55003.1 - 0.00029 21.1 0.1 0.85 9.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EGO55003.1 - 0.0015 18.0 2.8 0.049 13.0 0.1 2.6 2 0 0 2 2 2 1 AAA-like domain MMR_HSR1 PF01926.18 EGO55003.1 - 0.0019 18.1 0.3 1 9.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EGO55003.1 - 0.0025 17.6 0.0 3 7.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EGO55003.1 - 0.0089 15.5 0.0 3 7.2 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF3987 PF13148.1 EGO55003.1 - 0.014 13.9 0.4 0.7 8.3 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3987) ABC_ATPase PF09818.4 EGO55003.1 - 0.015 13.8 2.5 0.19 10.2 0.1 2.9 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_13 PF13166.1 EGO55003.1 - 0.018 13.5 0.2 8.6 4.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 EGO55003.1 - 0.019 14.8 2.5 0.63 9.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 EGO55003.1 - 0.02 14.5 0.1 5.8 6.6 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EGO55003.1 - 0.022 14.9 0.0 6.7 6.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 EGO55003.1 - 0.031 13.9 0.0 5.7 6.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Miro PF08477.8 EGO55003.1 - 0.054 13.9 0.2 24 5.4 0.0 3.6 4 0 0 4 4 4 0 Miro-like protein AAA PF00004.24 EGO55003.1 - 0.063 13.4 0.0 24 5.1 0.0 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EGO55003.1 - 0.14 10.9 0.6 6.5 5.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.13 EGO55003.1 - 0.17 11.4 0.2 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family KaiC PF06745.8 EGO55003.1 - 2.5 7.1 5.0 11 5.0 0.0 3.0 4 0 0 4 4 3 0 KaiC MFS_1 PF07690.11 EGO55004.1 - 1.3e-34 119.4 30.4 3.6e-33 114.7 7.9 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily CbtB PF09489.5 EGO55004.1 - 5 7.1 7.2 0.78 9.6 0.1 3.2 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) AXE1 PF05448.7 EGO55005.1 - 0.0022 16.5 0.1 0.0036 15.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF463 PF04317.7 EGO55005.1 - 0.037 12.5 0.0 0.048 12.2 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 Pyr_redox_2 PF07992.9 EGO55007.1 - 5e-14 52.6 0.0 7.8e-14 52.0 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO55007.1 - 1.1e-05 25.6 0.5 1.1e-05 25.6 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L2_C PF03947.13 EGO55007.1 - 0.015 15.1 0.0 0.049 13.4 0.0 1.8 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain DUF1068 PF06364.7 EGO55008.1 - 0.064 12.8 0.0 0.064 12.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) mRNA_triPase PF02940.10 EGO55011.1 - 4.1e-60 203.1 0.5 5.8e-60 202.6 0.4 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain PC_rep PF01851.17 EGO55012.1 - 8.1e-47 154.8 13.8 9e-09 35.1 0.0 9.4 8 0 0 8 8 8 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EGO55012.1 - 1.4e-17 63.7 2.5 1.5e-12 47.6 0.0 5.5 3 1 2 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 EGO55012.1 - 5.9e-08 32.9 1.8 5.9e-05 23.4 0.0 6.0 7 0 0 7 7 7 1 HEAT-like repeat HEAT PF02985.17 EGO55012.1 - 8.4e-06 25.4 5.6 1 9.6 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat DUF1546 PF07571.8 EGO55012.1 - 0.0054 16.8 0.1 1.4 9.0 0.0 3.9 3 1 1 4 4 4 1 Protein of unknown function (DUF1546) DUF1769 PF08588.5 EGO55013.1 - 1e-29 102.2 0.3 2.2e-29 101.1 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) TPX2 PF06886.6 EGO55015.1 - 0.18 11.8 3.0 0.28 11.2 2.1 1.2 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) ORC6 PF05460.8 EGO55015.1 - 4 6.4 8.1 4.4 6.3 5.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SnoaL_4 PF13577.1 EGO55016.1 - 6.5e-25 87.4 0.2 9e-25 87.0 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain FMO-like PF00743.14 EGO55017.1 - 1.1e-19 70.0 0.0 6.9e-09 34.4 0.0 3.4 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGO55017.1 - 3.9e-16 59.7 0.0 9e-15 55.2 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO55017.1 - 4e-08 32.5 1.2 0.00026 20.0 0.1 3.4 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGO55017.1 - 1.4e-06 28.1 0.0 0.0027 17.5 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGO55017.1 - 7.2e-05 22.7 0.1 0.00056 19.8 0.0 2.5 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO55017.1 - 0.0093 15.8 0.0 1.7 8.4 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO55017.1 - 0.011 14.7 1.7 1.9 7.3 0.0 2.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EGO55017.1 - 0.033 13.2 0.1 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family MFS_1 PF07690.11 EGO55018.1 - 3.2e-43 147.7 61.2 2.1e-42 145.1 39.1 3.5 2 1 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 EGO55018.1 - 1.8 9.0 6.6 2.5 8.5 0.2 3.6 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) SHP PF03579.8 EGO55018.1 - 1.9 7.8 8.0 5.4 6.4 0.9 3.7 3 0 0 3 3 3 0 Small hydrophobic protein NDUF_B8 PF05821.6 EGO55020.1 - 4.5e-07 29.6 0.3 6.2e-07 29.2 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.18 EGO55021.1 - 1.4e-74 250.6 1.1 4.5e-74 248.9 0.3 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO55021.1 - 2.6e-14 52.8 0.0 7.5e-14 51.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGO55021.1 - 0.00011 21.1 0.2 0.12 11.2 0.0 3.3 3 1 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 HSA PF07529.8 EGO55021.1 - 0.0099 15.6 8.4 0.0097 15.6 4.3 2.2 1 1 0 1 1 1 1 HSA Peptidase_S28 PF05577.7 EGO55023.1 - 1.4e-43 149.1 0.2 1.3e-42 145.9 0.1 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Ank_2 PF12796.2 EGO55026.1 - 4.9e-26 90.8 0.0 2e-09 37.6 0.0 3.8 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EGO55026.1 - 2.9e-14 52.0 0.1 0.00013 21.6 0.0 6.3 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.1 EGO55026.1 - 8.5e-10 38.8 0.0 0.05 14.1 0.0 6.1 1 1 6 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO55026.1 - 1.2e-09 37.4 0.0 0.0016 18.4 0.0 6.1 6 1 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.1 EGO55026.1 - 2.4e-05 24.4 0.1 0.14 12.4 0.0 4.6 4 1 2 6 6 6 1 Ankyrin repeats (many copies) Clr5 PF14420.1 EGO55027.1 - 8.2e-21 73.6 2.4 2.5e-20 72.1 1.6 1.9 1 0 0 1 1 1 1 Clr5 domain DUF1772 PF08592.6 EGO55028.1 - 0.021 14.5 1.3 0.021 14.5 0.9 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) DUF4131 PF13567.1 EGO55028.1 - 0.036 13.4 0.3 3.5 7.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) YjbE PF11106.3 EGO55028.1 - 0.062 13.2 7.6 1.5 8.8 2.0 2.3 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE Bax1-I PF01027.15 EGO55028.1 - 0.75 9.3 6.3 1 8.9 0.9 2.3 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 ANAPC15 PF15243.1 EGO55029.1 - 0.022 14.8 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 SLAC1 PF03595.12 EGO55030.1 - 9.5e-80 267.7 41.2 1.1e-79 267.4 28.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Cu-oxidase_2 PF07731.9 EGO55032.1 - 2e-40 137.4 0.2 2e-40 137.4 0.1 2.6 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGO55032.1 - 4.4e-40 136.0 5.4 3.1e-38 130.1 0.5 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EGO55032.1 - 5.9e-25 88.0 0.0 2.4e-24 86.0 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase RBM1CTR PF08081.6 EGO55032.1 - 0.087 12.5 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 RBM1CTR (NUC064) family GMC_oxred_C PF05199.8 EGO55033.1 - 1.5e-27 96.6 0.0 5.5e-27 94.8 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EGO55033.1 - 1.1e-23 83.8 0.0 2.8e-23 82.5 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 EGO55033.1 - 0.0081 16.0 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO55033.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HHH PF00633.18 EGO55033.1 - 0.039 13.6 0.4 3 7.7 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif FAD_binding_2 PF00890.19 EGO55033.1 - 0.042 12.6 0.0 0.21 10.3 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EGO55033.1 - 0.093 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GatB_N PF02934.10 EGO55034.1 - 4.1e-102 340.9 0.0 5.6e-102 340.4 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EGO55034.1 - 1.4e-09 37.8 0.0 3.2e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 GatB domain TSGP1 PF07771.6 EGO55034.1 - 1.7 8.5 4.1 2.9 7.7 2.9 1.3 1 0 0 1 1 1 0 Tick salivary peptide group 1 Tannase PF07519.6 EGO55035.1 - 8.6e-90 301.7 0.0 1.5e-89 300.8 0.0 1.3 1 1 0 1 1 1 1 Tannase and feruloyl esterase MFS_1 PF07690.11 EGO55036.1 - 1.2e-29 103.1 23.3 1.2e-29 103.1 16.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_47 PF01532.15 EGO55037.1 - 1.4e-127 426.1 0.0 1.6e-127 425.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Prenyltrans PF00432.16 EGO55039.1 - 0.0049 16.3 0.1 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Prenyltransferase and squalene oxidase repeat Endonuc-dimeris PF09124.5 EGO55040.1 - 0.067 12.8 0.5 10 5.8 0.0 2.2 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation Tropomyosin_1 PF12718.2 EGO55042.1 - 0.0014 18.4 31.9 0.0014 18.4 22.1 2.5 1 1 1 2 2 2 1 Tropomyosin like Bacillus_HBL PF05791.6 EGO55042.1 - 0.0052 16.1 13.1 0.015 14.7 3.3 2.3 1 1 1 2 2 2 2 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 EGO55042.1 - 0.032 13.8 39.2 0.14 11.7 14.2 2.6 1 1 1 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 EGO55042.1 - 0.11 12.3 39.0 0.1 12.4 14.5 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.6 EGO55042.1 - 0.26 10.7 20.1 2 7.8 2.6 3.4 1 1 2 3 3 3 0 Phage minor structural protein GP20 ATG16 PF08614.6 EGO55042.1 - 0.54 10.0 36.2 0.026 14.3 10.1 3.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) LMBR1 PF04791.11 EGO55042.1 - 0.7 8.4 9.0 1.5 7.3 6.1 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein DivIVA PF05103.8 EGO55042.1 - 1.7 8.7 31.1 3.1 7.8 11.8 3.5 2 1 1 3 3 3 0 DivIVA protein HlyD PF00529.15 EGO55042.1 - 1.9 7.6 25.0 4.1 6.6 16.9 1.8 1 1 0 1 1 1 0 HlyD family secretion protein GAS PF13851.1 EGO55042.1 - 3.9 6.6 32.2 0.7 9.0 10.3 2.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EGO55042.1 - 5.2 6.0 33.3 0.049 12.6 4.9 2.6 1 1 0 2 2 2 0 Autophagy protein Apg6 Striatin PF08232.7 EGO55042.1 - 8.4 6.7 33.2 3.5 7.9 11.8 3.5 1 1 1 2 2 2 0 Striatin family Fungal_trans PF04082.13 EGO55044.1 - 6.6e-24 84.1 0.5 9.9e-24 83.6 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO55044.1 - 8.3e-08 32.0 11.1 1.3e-07 31.3 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MR_MLE_C PF13378.1 EGO55045.1 - 2.5e-21 75.7 0.0 4.5e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EGO55045.1 - 1.8e-11 44.3 0.0 3.9e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EGO55045.1 - 3.7e-10 39.8 0.0 7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.10 EGO55045.1 - 0.13 11.3 0.0 0.44 9.6 0.0 1.7 2 0 0 2 2 2 0 Beta-galactosidase adh_short PF00106.20 EGO55046.1 - 4.3e-22 78.7 1.1 8.9e-22 77.7 0.8 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO55046.1 - 1.6e-13 50.9 0.0 2.1e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO55046.1 - 2.6e-08 33.7 0.5 5.3e-08 32.7 0.3 1.5 1 1 0 1 1 1 1 KR domain BTV_NS2 PF04514.7 EGO55047.1 - 0.23 10.2 7.7 0.31 9.8 5.3 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Pkinase PF00069.20 EGO55049.1 - 0.0023 17.1 0.0 0.0073 15.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain MFS_1 PF07690.11 EGO55050.1 - 2.6e-18 65.8 16.9 4e-18 65.2 11.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2542 PF10808.3 EGO55050.1 - 0.022 15.0 0.5 0.08 13.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2542) DUF2069 PF09842.4 EGO55050.1 - 0.18 11.7 9.1 0.16 11.9 3.3 2.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2069) ADH_zinc_N PF00107.21 EGO55051.1 - 1.1e-19 70.2 0.0 1.8e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO55051.1 - 4.9e-07 30.6 0.0 1.4e-06 29.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF456 PF04306.8 EGO55051.1 - 0.15 12.0 0.8 0.27 11.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) adh_short_C2 PF13561.1 EGO55052.1 - 3.9e-31 108.6 0.2 4.5e-31 108.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGO55052.1 - 2e-29 102.6 0.5 2.5e-29 102.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO55052.1 - 9.2e-15 54.7 0.2 1.2e-14 54.3 0.1 1.1 1 0 0 1 1 1 1 KR domain DapB_N PF01113.15 EGO55052.1 - 0.13 12.2 0.5 0.31 10.9 0.3 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_2 PF00703.16 EGO55053.1 - 3.5e-11 43.5 2.8 8e-11 42.3 0.4 2.7 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EGO55053.1 - 8e-06 25.5 0.0 1.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Caleosin PF05042.8 EGO55054.1 - 2.9e-55 186.5 0.0 3.7e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.1 EGO55054.1 - 0.0054 16.5 2.3 8.1 6.6 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EGO55054.1 - 0.12 11.7 0.5 40 3.8 0.0 3.5 3 0 0 3 3 3 0 EF hand HET PF06985.6 EGO55055.1 - 1.2e-23 83.8 0.0 2.9e-18 66.3 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Telomere_Sde2 PF13019.1 EGO55057.1 - 0.015 15.0 0.1 0.023 14.4 0.0 1.4 1 1 0 1 1 1 0 Telomere stability and silencing RRM_1 PF00076.17 EGO55059.1 - 7.3e-49 163.2 0.0 3.9e-14 52.0 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO55059.1 - 2.8e-43 145.7 0.1 3.3e-13 49.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO55059.1 - 2.6e-28 97.6 0.0 7.7e-11 41.6 0.0 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGO55059.1 - 1e-08 34.7 0.0 0.0062 16.2 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 EGO55059.1 - 0.00033 19.9 0.2 0.00091 18.5 0.2 1.7 1 0 0 1 1 1 1 Lsm interaction motif RRM_3 PF08777.6 EGO55059.1 - 0.0028 17.5 0.0 0.095 12.5 0.0 3.2 3 0 0 3 3 3 1 RNA binding motif Borrelia_P83 PF05262.6 EGO55059.1 - 0.054 11.7 5.3 0.092 11.0 3.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein TFIIA PF03153.8 EGO55059.1 - 0.21 11.4 16.4 0.027 14.3 4.6 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DUF3947 PF13135.1 EGO55059.1 - 5.1 7.3 17.7 12 6.1 12.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) MARVEL PF01284.18 EGO55060.1 - 1.2e-09 38.1 14.4 1.6e-09 37.7 10.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Tetraspannin PF00335.15 EGO55060.1 - 0.015 14.5 12.0 0.028 13.6 8.3 1.5 1 1 0 1 1 1 0 Tetraspanin family DUF4199 PF13858.1 EGO55060.1 - 0.077 12.9 14.1 0.56 10.1 6.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF1056 PF06341.6 EGO55060.1 - 0.1 12.6 0.3 0.1 12.6 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) DUF4149 PF13664.1 EGO55060.1 - 0.65 10.0 11.8 0.34 11.0 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Got1 PF04178.7 EGO55060.1 - 0.71 10.0 13.5 0.08 13.0 5.4 2.2 1 1 1 2 2 2 0 Got1/Sft2-like family BRI3BP PF14965.1 EGO55060.1 - 0.85 8.9 5.0 1 8.6 3.5 1.2 1 0 0 1 1 1 0 Negative regulator of p53/TP53 YfhO PF09586.5 EGO55060.1 - 0.97 7.3 12.1 1.2 7.0 8.4 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO FAD_binding_3 PF01494.14 EGO55061.1 - 1.1e-79 268.0 0.0 1.5e-79 267.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EGO55061.1 - 0.00034 20.5 0.0 0.00058 19.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO55061.1 - 0.016 15.2 1.5 0.048 13.6 1.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO55061.1 - 0.016 14.1 1.2 0.045 12.6 0.9 1.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EGO55061.1 - 0.043 12.9 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EGO55061.1 - 0.065 12.1 0.1 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Glyco_trans_1_3 PF13528.1 EGO55061.1 - 0.072 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 Pyr_redox_3 PF13738.1 EGO55061.1 - 0.11 12.5 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGO55061.1 - 0.28 9.9 3.2 0.43 9.3 1.8 1.5 1 1 0 1 1 1 0 FAD binding domain BNR_2 PF13088.1 EGO55062.1 - 4.9e-17 62.1 2.9 3.3e-09 36.4 0.1 2.7 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EGO55062.1 - 1.2e-06 27.4 27.6 0.029 14.1 0.6 6.5 6 0 0 6 6 6 4 BNR/Asp-box repeat Mo-co_dimer PF03404.11 EGO55062.1 - 0.0002 21.0 2.7 0.44 10.1 0.0 4.4 4 1 0 5 5 5 2 Mo-co oxidoreductase dimerisation domain DUF4185 PF13810.1 EGO55062.1 - 0.011 14.6 5.3 0.36 9.6 0.7 3.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4185) BNR_3 PF13859.1 EGO55062.1 - 0.024 13.6 0.0 5.6 5.9 0.0 2.9 2 1 1 3 3 3 0 BNR repeat-like domain ADH_N PF08240.7 EGO55063.1 - 1.1e-26 92.7 1.5 1.7e-26 92.0 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 EGO55063.1 - 2.3e-08 33.5 2.9 2.3e-08 33.5 2.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 EGO55063.1 - 9.4e-08 31.6 0.0 0.00013 21.4 0.0 2.8 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Cystatin PF00031.16 EGO55063.1 - 0.07 13.2 0.2 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Cystatin domain FANCL_C PF11793.3 EGO55063.1 - 0.1 12.5 1.1 0.19 11.7 0.8 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain SSP160 PF06933.6 EGO55064.1 - 6.5 4.5 11.1 9 4.1 7.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 WHEP-TRS PF00458.15 EGO55066.1 - 0.0069 16.0 0.7 0.014 15.0 0.5 1.5 1 0 0 1 1 1 1 WHEP-TRS domain CFEM PF05730.6 EGO55067.1 - 1.1e-11 44.3 12.9 1.1e-11 44.3 8.9 1.3 1 1 0 1 1 1 1 CFEM domain DUF883 PF05957.8 EGO55069.1 - 0.015 15.6 23.4 0.89 9.9 1.8 4.7 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) CsbD PF05532.7 EGO55069.1 - 0.075 12.7 55.9 20 4.9 11.1 7.2 1 1 3 4 4 4 0 CsbD-like DUF3618 PF12277.3 EGO55069.1 - 0.1 12.6 0.3 0.1 12.6 0.2 3.9 5 1 0 5 5 5 0 Protein of unknown function (DUF3618) YtxH PF12732.2 EGO55069.1 - 0.21 11.9 26.5 1.5e+04 -13.1 18.3 5.0 1 1 0 1 1 1 0 YtxH-like protein BMFP PF04380.8 EGO55069.1 - 0.7 10.0 9.9 34 4.6 0.1 5.3 1 1 5 6 6 6 0 Membrane fusogenic activity LEA_4 PF02987.11 EGO55069.1 - 0.99 9.3 52.4 0.31 10.9 4.8 6.2 5 2 1 6 6 6 0 Late embryogenesis abundant protein ECH PF00378.15 EGO55070.1 - 2.9e-46 157.5 0.1 3e-43 147.7 0.0 2.3 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family HET PF06985.6 EGO55073.1 - 1.4e-18 67.4 0.0 2.1e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ELYS PF13934.1 EGO55074.1 - 1.3e-59 201.7 0.0 1.6e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly Glyphos_transf PF04464.9 EGO55074.1 - 0.13 10.9 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase HUN PF08729.5 EGO55075.1 - 1.7e-13 50.2 0.5 4.3e-13 48.9 0.4 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.5 EGO55076.1 - 3.5e-31 106.8 0.4 8e-31 105.7 0.0 1.8 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EGO55076.1 - 1.9e-18 65.8 2.4 3.7e-18 64.8 1.6 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal MFS_1 PF07690.11 EGO55077.1 - 2.3e-33 115.3 35.7 2.3e-33 115.3 24.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Dicty_REP PF05086.7 EGO55077.1 - 4.9 4.7 4.3 6.2 4.4 3.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_hydro_43 PF04616.9 EGO55078.1 - 2.7e-15 56.2 1.3 3.9e-15 55.6 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 IL13 PF03487.8 EGO55079.1 - 3.8 7.2 5.6 21 4.9 0.4 3.5 2 0 0 2 2 2 0 Interleukin-13 Linker_histone PF00538.14 EGO55081.1 - 6.9e-23 80.5 0.1 1.5e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family Gti1_Pac2 PF09729.4 EGO55082.1 - 8.2e-47 159.1 9.1 5.9e-46 156.3 3.2 2.8 2 1 0 2 2 2 1 Gti1/Pac2 family PSRT PF07636.6 EGO55083.1 - 0.086 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 PSRT tRNA-synt_2 PF00152.15 EGO55086.1 - 7.5e-69 232.0 0.0 1e-68 231.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGO55086.1 - 1.6e-07 31.0 0.0 2.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGO55086.1 - 0.0048 16.1 0.1 0.83 8.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF2263 PF10021.4 EGO55088.1 - 3e-15 56.5 0.0 5.2e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Sec23_trunk PF04811.10 EGO55090.1 - 5.6e-52 176.5 0.0 1.2e-51 175.4 0.0 1.5 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGO55090.1 - 1.6e-23 82.0 0.1 2.8e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGO55090.1 - 2.1e-18 66.6 0.0 7e-18 64.9 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGO55090.1 - 3.7e-17 61.5 4.1 7.5e-17 60.6 2.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGO55090.1 - 4.1e-05 23.1 0.0 9.9e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat CPSF100_C PF13299.1 EGO55091.1 - 1.2e-39 136.0 0.0 3e-39 134.8 0.0 1.7 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EGO55091.1 - 7.2e-29 100.2 0.0 2e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EGO55091.1 - 8.7e-08 31.8 0.0 2.1e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Glyco_hydro_17 PF00332.13 EGO55092.1 - 4.8e-07 29.1 2.6 2e-06 27.0 0.5 2.4 1 1 0 2 2 2 1 Glycosyl hydrolases family 17 SR-25 PF10500.4 EGO55092.1 - 0.0049 16.3 3.1 0.0099 15.3 2.1 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4604 PF15377.1 EGO55092.1 - 0.032 14.4 0.2 0.032 14.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Aminotran_1_2 PF00155.16 EGO55093.1 - 1.5e-34 119.5 0.0 1.8e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGO55093.1 - 0.0021 16.4 0.0 0.0033 15.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF2540 PF10802.3 EGO55093.1 - 0.041 13.5 0.1 0.37 10.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) Glucan_synthase PF02364.10 EGO55094.1 - 0 1434.0 0.0 0 1433.1 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EGO55094.1 - 5.6e-39 132.6 2.5 5.8e-39 132.6 0.4 2.1 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SprT-like PF10263.4 EGO55096.1 - 4.7e-51 172.5 0.1 8.1e-51 171.7 0.1 1.4 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.14 EGO55096.1 - 3.2e-05 24.1 1.0 8.2e-05 22.7 0.7 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO55096.1 - 0.00054 20.2 3.0 0.0022 18.3 2.1 2.1 1 0 0 1 1 1 1 HMG-box domain Virulence_fact PF13769.1 EGO55096.1 - 0.15 11.9 3.3 0.11 12.3 0.2 2.3 2 0 0 2 2 2 0 Virulence factor Mog1 PF04603.7 EGO55097.1 - 1.4e-16 60.7 0.0 4.3e-16 59.1 0.0 1.7 1 1 0 1 1 1 1 Ran-interacting Mog1 protein HIT PF01230.18 EGO55098.1 - 5.5e-22 78.1 0.1 8.7e-22 77.4 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGO55098.1 - 2e-12 47.3 0.1 3.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EGO55098.1 - 2.2e-05 24.0 0.1 3.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.15 EGO55099.1 - 2.8e-46 156.9 0.0 4.8e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGO55099.1 - 4.2e-16 58.8 0.0 2.1e-15 56.5 0.0 2.3 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGO55099.1 - 4e-14 52.7 0.2 2.2e-13 50.3 0.0 2.3 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain DASH_Dam1 PF08653.5 EGO55100.1 - 8.6e-27 92.6 1.4 1.3e-26 92.1 0.9 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF167 PF02594.11 EGO55101.1 - 1e-18 66.9 0.4 1.4e-18 66.5 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Redoxin PF08534.5 EGO55102.1 - 2.2e-29 101.8 0.0 2.7e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EGO55102.1 - 6e-06 25.9 0.0 7.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family CoA_trans PF01144.18 EGO55103.1 - 4.3e-101 336.6 1.8 5.6e-59 198.9 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase IBR PF01485.16 EGO55105.1 - 7.3e-23 80.2 43.4 2.7e-12 46.3 4.1 4.5 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 EGO55105.1 - 1.1e-05 25.2 6.5 1.1e-05 25.2 4.5 4.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO55105.1 - 5.2e-05 22.9 3.2 5.2e-05 22.9 2.2 3.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EGO55105.1 - 0.00018 21.1 4.1 0.00018 21.1 2.8 4.7 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.3 EGO55105.1 - 0.1 12.9 0.1 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-C3HC4_4 PF15227.1 EGO55105.1 - 0.46 10.4 34.1 0.27 11.1 2.6 4.7 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGO55105.1 - 2.7 7.8 40.4 0.022 14.4 4.8 4.2 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGO55105.1 - 5.7 6.7 20.8 0.38 10.5 1.2 3.6 3 1 0 3 3 3 0 RING-type zinc-finger FHA PF00498.21 EGO55106.1 - 4e-15 55.6 0.0 6.6e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain MIP-T3 PF10243.4 EGO55106.1 - 0.033 12.6 29.9 0.041 12.3 20.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AAA_16 PF13191.1 EGO55107.1 - 9.7e-06 25.6 0.0 4.1e-05 23.6 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain PGAP1 PF07819.8 EGO55107.1 - 0.0032 17.0 0.0 0.0076 15.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.1 EGO55107.1 - 0.0047 17.0 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF676 PF05057.9 EGO55107.1 - 0.005 16.1 0.0 0.0087 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Dot_icm_IcmQ PF09475.5 EGO55107.1 - 0.016 14.4 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) HCMV_UL139 PF12507.3 EGO55107.1 - 0.16 12.1 0.5 0.4 10.8 0.4 1.6 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein AAA_23 PF13476.1 EGO55108.1 - 0.00025 21.4 0.1 0.00027 21.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain Macoilin PF09726.4 EGO55108.1 - 0.00041 18.7 14.3 0.00063 18.1 9.9 1.3 1 0 0 1 1 1 1 Transmembrane protein Golgin_A5 PF09787.4 EGO55108.1 - 0.00065 18.3 10.8 0.0008 18.0 7.5 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 IncA PF04156.9 EGO55108.1 - 0.001 18.6 9.1 0.002 17.7 5.9 1.4 1 1 0 1 1 1 1 IncA protein TipAS PF07739.8 EGO55108.1 - 0.0023 18.2 1.6 0.0036 17.6 1.1 1.3 1 0 0 1 1 1 1 TipAS antibiotic-recognition domain RAP1 PF07218.6 EGO55108.1 - 0.014 13.5 14.1 0.018 13.2 9.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDC45 PF02724.9 EGO55108.1 - 0.028 12.4 10.8 0.035 12.1 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein TBPIP PF07106.8 EGO55108.1 - 0.029 13.9 6.0 0.038 13.5 4.2 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2217 PF10265.4 EGO55108.1 - 0.033 12.9 9.2 0.04 12.6 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Period_C PF12114.3 EGO55108.1 - 0.047 13.2 15.1 0.059 12.9 10.5 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Complex1_LYR_2 PF13233.1 EGO55108.1 - 0.061 13.8 0.4 0.085 13.3 0.3 1.3 1 0 0 1 1 1 0 Complex1_LYR-like V_ATPase_I PF01496.14 EGO55108.1 - 0.31 8.8 1.9 0.34 8.6 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.1 EGO55108.1 - 0.35 10.8 12.3 0.53 10.2 3.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) CytochromB561_N PF09786.4 EGO55108.1 - 0.43 8.9 12.7 0.51 8.7 8.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Ndc1_Nup PF09531.5 EGO55108.1 - 1.7 6.9 6.9 2 6.7 4.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Prefoldin_3 PF13758.1 EGO55108.1 - 3.3 7.5 9.3 1.2 8.9 0.5 2.4 1 1 1 2 2 2 0 Prefoldin subunit bZIP_2 PF07716.10 EGO55108.1 - 4.9 7.0 12.7 9.5 6.1 2.7 2.3 2 0 0 2 2 2 0 Basic region leucine zipper TFIIF_alpha PF05793.7 EGO55108.1 - 7.6 4.7 22.5 14 3.9 15.6 1.4 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TSC22 PF01166.13 EGO55108.1 - 8.3 6.4 11.0 17 5.4 1.1 2.7 1 1 2 3 3 3 0 TSC-22/dip/bun family DUF1395 PF07160.7 EGO55109.1 - 0.0077 15.7 1.2 0.0099 15.3 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1395) Suppressor_APC PF11414.3 EGO55109.1 - 0.014 15.1 2.7 0.022 14.5 1.9 1.3 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein DUF288 PF03385.12 EGO55109.1 - 0.024 13.1 0.1 0.034 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF288 bZIP_1 PF00170.16 EGO55109.1 - 0.081 12.8 9.2 0.12 12.3 1.2 2.3 1 1 1 2 2 2 0 bZIP transcription factor Astro_capsid PF03115.9 EGO55109.1 - 0.55 8.4 4.5 0.6 8.2 3.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CobT PF06213.7 EGO55109.1 - 0.84 8.7 14.3 1 8.4 9.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF972 PF06156.8 EGO55109.1 - 0.86 9.9 7.5 1.4 9.3 4.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Daxx PF03344.10 EGO55109.1 - 7.6 4.8 16.8 8.1 4.7 11.6 1.1 1 0 0 1 1 1 0 Daxx Family Tup_N PF08581.5 EGO55109.1 - 8.5 6.6 10.1 0.43 10.8 3.2 1.6 2 0 0 2 2 2 0 Tup N-terminal Gin PF10764.4 EGO55111.1 - 0.0053 16.4 0.8 0.01 15.5 0.6 1.4 1 0 0 1 1 1 1 Inhibitor of sigma-G Gin zf-C3HC4_3 PF13920.1 EGO55111.1 - 0.078 12.6 1.2 0.12 12.0 0.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_clus PF00172.13 EGO55111.1 - 8.8 6.3 8.8 1.3 9.0 1.4 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1476 PF07345.6 EGO55115.1 - 0.001 19.2 0.1 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1476) DUF4100 PF13352.1 EGO55115.1 - 0.12 11.7 0.9 0.15 11.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) TauD PF02668.11 EGO55116.1 - 5.8e-56 190.0 0.1 1e-55 189.1 0.1 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EGO55116.1 - 0.019 13.8 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 CsiD DUF971 PF06155.7 EGO55116.1 - 0.027 14.9 0.0 0.076 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF971) DUF2353 PF09789.4 EGO55116.1 - 0.06 12.5 4.7 0.1 11.8 3.3 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) IncA PF04156.9 EGO55116.1 - 0.27 10.8 0.4 0.58 9.7 0.3 1.5 1 0 0 1 1 1 0 IncA protein Ribosomal_S10 PF00338.17 EGO55117.1 - 8.1e-30 102.5 0.5 1e-29 102.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.11 EGO55118.1 - 3.2e-09 36.0 0.1 6.2e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 CUE domain Nucleoporin_FG PF13634.1 EGO55119.1 - 0.00024 21.3 42.8 0.00024 21.3 29.7 5.8 2 2 2 4 4 4 2 Nucleoporin FG repeat region zf-CCCH PF00642.19 EGO55119.1 - 0.0023 17.5 0.7 0.0053 16.3 0.5 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) p450 PF00067.17 EGO55120.1 - 1.2e-62 211.9 0.0 1.7e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RED_N PF07808.8 EGO55121.1 - 6.2 5.9 8.9 11 5.1 6.2 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region Ndc1_Nup PF09531.5 EGO55121.1 - 7.5 4.8 8.6 9 4.5 5.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF605 PF04652.11 EGO55122.1 - 0.6 9.4 6.9 1.1 8.5 4.8 1.4 1 0 0 1 1 1 0 Vta1 like DUF605 PF04652.11 EGO55124.1 - 4.7 6.5 10.7 6 6.1 7.4 1.1 1 0 0 1 1 1 0 Vta1 like Zip PF02535.17 EGO55125.1 - 0.28 10.1 6.4 0.3 10.0 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Trypan_PARP PF05887.6 EGO55129.1 - 0.039 13.7 0.1 0.049 13.4 0.1 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Cep57_CLD_2 PF14197.1 EGO55130.1 - 0.0018 18.1 0.8 0.0032 17.3 0.6 1.4 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.4 EGO55130.1 - 0.0076 16.1 0.6 0.011 15.6 0.4 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 adh_short PF00106.20 EGO55131.1 - 2.8e-29 102.1 2.3 4.5e-29 101.5 1.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO55131.1 - 2.6e-27 96.1 0.1 3.1e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO55131.1 - 1.5e-15 57.3 1.2 2.6e-15 56.5 0.8 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO55131.1 - 0.00018 21.0 0.4 0.0019 17.6 0.3 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peripla_BP_4 PF13407.1 EGO55131.1 - 0.0046 16.3 0.1 0.0069 15.7 0.0 1.3 1 1 0 1 1 1 1 Periplasmic binding protein domain 3HCDH_N PF02737.13 EGO55131.1 - 0.12 12.0 0.4 0.22 11.1 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.20 EGO55132.1 - 0.00012 21.3 0.0 0.0036 16.4 0.0 2.8 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO55132.1 - 0.0007 18.7 0.0 0.0018 17.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase zf-C2H2 PF00096.21 EGO55134.1 - 2.7e-09 36.8 19.3 0.00025 21.1 3.7 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO55134.1 - 5.6e-09 35.8 10.9 0.00028 21.0 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO55134.1 - 0.014 15.7 17.7 0.36 11.2 0.3 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Phostensin_N PF13916.1 EGO55134.1 - 0.62 10.0 5.0 2.5 8.1 3.5 2.1 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal AT_hook PF02178.14 EGO55134.1 - 1.1 9.1 5.2 4.6 7.2 3.6 2.2 1 0 0 1 1 1 0 AT hook motif zf-MYND PF01753.13 EGO55135.1 - 1.8e-13 50.0 10.3 4.5e-13 48.8 7.2 1.7 1 0 0 1 1 1 1 MYND finger DUF4470 PF14737.1 EGO55135.1 - 1.3e-10 40.9 0.0 8.1e-09 35.1 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4470) WSC PF01822.14 EGO55136.1 - 3.8e-18 65.1 9.3 3.8e-18 65.1 6.5 1.8 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 EGO55136.1 - 9.7e-06 24.8 0.8 2.3e-05 23.5 0.5 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4366 PF14283.1 EGO55136.1 - 0.00088 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) TMEM154 PF15102.1 EGO55136.1 - 0.0032 17.1 1.0 0.0053 16.4 0.7 1.3 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.6 EGO55136.1 - 0.0067 16.0 2.2 0.011 15.3 1.5 1.3 1 0 0 1 1 1 1 Podoplanin DUF4448 PF14610.1 EGO55136.1 - 0.06 12.8 0.2 0.087 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.1 EGO55136.1 - 0.067 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TrbL PF04610.9 EGO55136.1 - 0.17 11.5 1.4 0.26 10.9 1.0 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein RAP1 PF07218.6 EGO55136.1 - 0.23 9.5 11.3 0.32 9.0 7.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1180 PF06679.7 EGO55136.1 - 0.69 9.7 3.9 0.69 9.7 1.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Med3 PF11593.3 EGO55136.1 - 2.1 7.4 8.3 3.6 6.7 5.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF515 PF04415.7 EGO55136.1 - 6.7 4.8 16.9 0.066 11.4 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF515) TrbI_Ftype PF09677.5 EGO55137.1 - 0.015 15.1 0.6 0.034 13.9 0.4 1.7 1 1 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) Maf_N PF08383.6 EGO55137.1 - 0.066 12.7 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Maf N-terminal region DEC-1_N PF04625.8 EGO55138.1 - 0.31 9.6 1.8 0.4 9.3 1.3 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region tRNA-synt_His PF13393.1 EGO55140.1 - 2.4e-42 145.1 0.0 1.8e-41 142.2 0.0 1.9 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EGO55140.1 - 4.1e-16 59.0 0.0 6.9e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGO55140.1 - 3.7e-11 42.8 0.0 1e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EGO55140.1 - 0.0018 17.0 0.0 0.0096 14.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EGO55140.1 - 0.055 12.6 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Phage_H_T_join PF05521.6 EGO55141.1 - 0.15 12.3 0.2 0.15 12.3 0.1 1.8 2 0 0 2 2 2 0 Phage head-tail joining protein Xan_ur_permease PF00860.15 EGO55144.1 - 1.6e-62 211.2 34.7 3.6e-61 206.8 24.1 2.1 1 1 0 1 1 1 1 Permease family zf-C2H2_jaz PF12171.3 EGO55145.1 - 8.7e-11 41.6 19.9 0.00015 21.7 0.6 4.7 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGO55145.1 - 1.3e-08 34.7 21.0 0.00013 22.0 0.6 5.4 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EGO55145.1 - 3.3e-08 33.4 33.5 0.032 14.5 0.8 6.7 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO55145.1 - 2.3e-06 27.5 26.3 0.14 12.4 0.4 5.9 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO55145.1 - 1.3e-05 25.1 29.1 0.11 12.9 0.7 6.2 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGO55145.1 - 3.9e-05 23.6 21.4 0.033 14.2 0.8 5.3 3 2 3 6 6 6 2 C2H2 type zinc-finger (2 copies) Rpr2 PF04032.11 EGO55145.1 - 0.14 12.0 3.0 0.65 9.9 2.0 2.2 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-Di19 PF05605.7 EGO55145.1 - 0.21 11.7 0.4 0.21 11.7 0.3 4.5 4 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EGO55145.1 - 0.52 10.2 0.1 0.52 10.2 0.0 5.1 6 0 0 6 6 6 0 C2H2-type zinc finger AKAP95 PF04988.7 EGO55145.1 - 0.58 9.9 9.2 2.6 7.8 0.7 2.9 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-met PF12874.2 EGO55146.1 - 6.6e-14 51.5 22.1 0.0023 18.0 0.1 6.4 6 1 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EGO55146.1 - 2.3e-10 40.1 36.4 0.1 12.9 0.2 7.8 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EGO55146.1 - 6.5e-10 38.8 27.0 5.7e-05 23.1 2.7 6.6 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGO55146.1 - 2.8e-09 37.0 24.6 0.00028 20.9 5.5 5.4 2 2 3 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EGO55146.1 - 1.9e-07 30.8 30.1 0.018 15.3 0.2 7.6 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGO55146.1 - 6.8e-05 22.6 24.3 0.004 17.0 0.1 6.2 6 0 0 6 6 6 3 C2H2-type zinc finger zf-RING_2 PF13639.1 EGO55146.1 - 0.015 15.1 3.8 0.015 15.1 2.6 3.2 3 2 1 4 4 4 0 Ring finger domain zf-Di19 PF05605.7 EGO55146.1 - 0.029 14.4 0.4 0.029 14.4 0.3 5.2 4 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding Ecl1 PF12855.2 EGO55146.1 - 3.4 7.0 10.1 0.44 9.8 0.2 3.8 4 0 0 4 4 4 0 Life-span regulatory factor C1_1 PF00130.17 EGO55146.1 - 5.1 6.9 17.4 1.7 8.4 1.3 4.5 3 3 2 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) WD40 PF00400.27 EGO55147.1 - 1.4e-29 100.8 7.2 3.5e-09 36.1 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Cornichon PF03311.9 EGO55148.1 - 5.7e-54 181.6 10.5 6.4e-54 181.5 7.3 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M24 PF00557.19 EGO55149.1 - 4.2e-46 157.1 0.1 5.1e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EGO55149.1 - 1.5e-05 24.7 3.6 3.5e-05 23.5 2.5 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EGO55149.1 - 1.1 8.9 4.4 2.6 7.7 3.0 1.7 1 0 0 1 1 1 0 HIT zinc finger EGF_CA PF07645.10 EGO55149.1 - 8.9 6.3 8.3 2.9 7.9 1.0 2.6 1 1 1 2 2 2 0 Calcium-binding EGF domain FAD_binding_3 PF01494.14 EGO55150.1 - 1.9e-22 79.8 0.0 3.9e-22 78.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EGO55150.1 - 2.8e-05 24.4 0.0 0.00085 19.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO55150.1 - 5.6e-05 22.2 0.0 0.0001 21.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO55150.1 - 8.2e-05 22.5 0.1 0.00026 20.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO55150.1 - 0.00033 20.5 0.0 0.0009 19.1 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO55150.1 - 0.00083 18.5 0.2 0.0045 16.1 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGO55150.1 - 0.0015 17.0 0.1 0.0023 16.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.5 EGO55150.1 - 0.0018 17.1 0.0 0.0035 16.2 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase GIDA PF01134.17 EGO55150.1 - 0.0024 16.7 0.0 0.0046 15.8 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EGO55150.1 - 0.0097 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EGO55150.1 - 0.045 13.3 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 EGO55150.1 - 0.082 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EGO55150.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 EGO55150.1 - 0.18 11.5 0.0 0.42 10.3 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NMT_C PF02799.10 EGO55151.1 - 1.4e-79 265.8 0.2 2.1e-79 265.3 0.1 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 EGO55151.1 - 2.5e-67 225.5 0.0 4.2e-67 224.8 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Abhydrolase_6 PF12697.2 EGO55151.1 - 1.1e-17 64.7 0.1 2e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO55151.1 - 1.4e-08 34.5 0.0 3.3e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Acetyltransf_9 PF13527.1 EGO55151.1 - 4e-06 26.6 0.1 2.6e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Abhydrolase_1 PF00561.15 EGO55151.1 - 3.8e-05 23.3 0.0 0.006 16.1 0.0 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Acetyltransf_3 PF13302.1 EGO55151.1 - 0.0074 16.4 0.1 0.02 15.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CMS1 PF14617.1 EGO55151.1 - 0.012 14.6 1.0 0.023 13.7 0.7 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Acetyltransf_7 PF13508.1 EGO55151.1 - 0.02 15.0 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO55151.1 - 0.08 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein eIF3_subunit PF08597.5 EGO55151.1 - 0.087 12.3 8.2 0.14 11.7 5.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Hydrolase_4 PF12146.3 EGO55151.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_6 PF12697.2 EGO55153.1 - 6.3e-15 55.6 1.7 9.4e-15 55.1 1.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO55153.1 - 2.6e-14 53.1 0.0 5.1e-14 52.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGO55153.1 - 6e-07 29.2 0.3 1e-06 28.4 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EGO55153.1 - 3.3e-06 26.8 0.0 5.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EGO55153.1 - 0.0011 18.7 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 EGO55153.1 - 0.005 16.4 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EGO55153.1 - 0.021 14.4 0.1 0.073 12.6 0.0 1.8 1 1 0 1 1 1 0 PGAP1-like protein DUF218 PF02698.12 EGO55153.1 - 0.028 13.9 0.0 0.068 12.6 0.0 1.6 2 0 0 2 2 2 0 DUF218 domain Thioesterase PF00975.15 EGO55153.1 - 0.035 14.3 0.2 0.088 13.0 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain Cutinase PF01083.17 EGO55153.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Cutinase AXE1 PF05448.7 EGO55153.1 - 0.11 10.9 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.3 EGO55153.1 - 0.2 10.9 0.0 0.47 9.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) CTD PF12815.2 EGO55155.1 - 1.8e-28 99.4 60.5 3.9e-21 75.7 28.3 5.0 2 1 3 5 5 5 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 EGO55155.1 - 1.8e-25 88.4 0.1 3.1e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EGO55155.1 - 8.6e-19 67.9 7.9 8.6e-19 67.9 5.5 2.5 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EGO55155.1 - 0.00055 19.5 22.2 0.011 15.4 1.7 5.3 6 0 0 6 6 6 2 KOW motif PPV_E1_N PF00524.13 EGO55155.1 - 0.0019 18.4 1.1 0.0019 18.4 0.8 1.8 2 0 0 2 2 2 1 E1 Protein, N terminal domain zf-C2H2_3 PF13878.1 EGO55156.1 - 1.1 8.8 5.1 0.69 9.5 0.1 2.9 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO DZR PF12773.2 EGO55156.1 - 7.4 6.4 17.7 0.039 13.7 1.6 3.4 3 1 0 3 3 3 0 Double zinc ribbon Oxidored_molyb PF00174.14 EGO55157.1 - 2.4e-52 176.7 0.0 4.1e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EGO55157.1 - 1.2e-20 73.4 0.1 5e-13 48.8 0.0 3.0 2 1 1 3 3 3 2 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 EGO55157.1 - 2.1e-12 46.6 0.0 3.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3506 PF12014.3 EGO55158.1 - 1.6e-53 180.1 0.0 3.2e-53 179.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 EGO55158.1 - 2.3e-09 36.8 0.1 5.2e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO55158.1 - 2.3e-07 30.2 0.0 6.3e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EGO55158.1 - 0.041 13.5 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain Serum_albumin PF00273.15 EGO55158.1 - 0.22 10.9 0.1 0.39 10.1 0.0 1.3 1 0 0 1 1 1 0 Serum albumin family Cupin_2 PF07883.6 EGO55159.1 - 3.1e-08 32.9 0.1 5.2e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EGO55159.1 - 9.6e-06 25.0 0.0 1.2e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EGO55159.1 - 0.0014 17.9 0.0 0.0027 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Abhydrolase_6 PF12697.2 EGO55160.1 - 0.00064 19.6 0.6 0.0019 18.1 0.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family NmrA PF05368.8 EGO55162.1 - 2.5e-28 98.9 0.0 7e-28 97.4 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO55162.1 - 1.4e-09 38.2 0.0 2.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EGO55162.1 - 0.0044 17.3 0.1 0.017 15.4 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EGO55162.1 - 0.005 16.7 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EGO55162.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO55162.1 - 0.017 13.8 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EGO55162.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Hce2 PF14856.1 EGO55163.1 - 8.4e-23 80.0 0.5 1e-22 79.8 0.4 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor DUF3994 PF13159.1 EGO55163.1 - 0.033 14.4 0.1 0.089 13.0 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3994) Hce2 PF14856.1 EGO55164.1 - 1.3e-22 79.5 0.2 1.6e-22 79.1 0.1 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor GST_C PF00043.20 EGO55165.1 - 3.3e-07 30.1 0.0 5.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGO55165.1 - 2e-06 27.9 0.0 4.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO55165.1 - 3.8e-06 26.7 0.0 1.1e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO55165.1 - 4.5e-05 23.8 0.0 7.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGO55165.1 - 0.00025 20.9 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGO55165.1 - 0.00062 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain JAB PF01398.16 EGO55166.1 - 1.2e-15 57.1 0.0 2.3e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 EGO55166.1 - 6.7e-07 29.2 0.1 2.6e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 USP8 dimerisation domain Prok-JAB PF14464.1 EGO55166.1 - 1.6e-05 24.4 0.0 4.3e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF948 PF06103.6 EGO55166.1 - 0.049 13.4 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Mod_r PF07200.8 EGO55166.1 - 0.052 13.4 1.1 0.11 12.4 0.7 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Cep57_MT_bd PF06657.8 EGO55166.1 - 0.16 11.9 1.7 0.37 10.7 0.4 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ERM PF00769.14 EGO55166.1 - 0.26 10.7 7.8 0.43 10.0 5.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DegS PF05384.6 EGO55166.1 - 0.27 10.4 3.8 0.46 9.6 2.6 1.3 1 0 0 1 1 1 0 Sensor protein DegS DUF972 PF06156.8 EGO55166.1 - 0.4 11.0 1.6 0.69 10.2 0.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) AAA PF00004.24 EGO55168.1 - 1e-42 145.4 0.0 1.9e-42 144.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EGO55168.1 - 8.6e-30 102.4 0.1 7.1e-29 99.4 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EGO55168.1 - 1.1e-21 76.4 4.1 1.1e-21 76.4 2.8 2.4 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EGO55168.1 - 4.2e-06 27.5 0.7 4.3e-05 24.3 0.0 3.0 2 1 1 3 3 2 1 AAA domain RuvB_N PF05496.7 EGO55168.1 - 6.9e-06 25.2 0.0 1.3e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EGO55168.1 - 1.7e-05 24.3 1.3 0.15 11.4 0.1 3.3 1 1 1 3 3 3 2 AAA domain AAA_22 PF13401.1 EGO55168.1 - 1.8e-05 24.8 0.1 0.0017 18.5 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGO55168.1 - 2.5e-05 24.0 0.0 0.00015 21.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EGO55168.1 - 2.5e-05 23.7 0.0 6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EGO55168.1 - 2.6e-05 24.1 0.0 5.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGO55168.1 - 4.2e-05 23.6 0.0 0.0096 16.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.8 EGO55168.1 - 5.7e-05 22.0 0.0 9.2e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EGO55168.1 - 7.7e-05 22.7 1.1 0.0013 18.7 0.0 3.0 3 1 1 4 4 3 1 AAA ATPase domain DUF815 PF05673.8 EGO55168.1 - 0.00022 20.2 0.0 0.0018 17.2 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EGO55168.1 - 0.00031 20.6 0.0 0.00075 19.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGO55168.1 - 0.00056 19.8 0.0 0.0031 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EGO55168.1 - 0.0042 16.2 0.1 0.17 10.9 0.0 2.6 1 1 1 2 2 2 1 Zeta toxin AAA_24 PF13479.1 EGO55168.1 - 0.0068 16.0 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO55168.1 - 0.009 16.3 0.1 0.023 14.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EGO55168.1 - 0.013 15.2 0.0 0.064 13.0 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EGO55168.1 - 0.019 14.1 0.0 0.066 12.3 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EGO55168.1 - 0.02 14.5 0.0 0.33 10.5 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 EGO55168.1 - 0.02 14.5 0.3 0.22 11.1 0.0 2.3 2 1 1 3 3 3 0 Archaeal ATPase ResIII PF04851.10 EGO55168.1 - 0.027 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Torsin PF06309.6 EGO55168.1 - 0.036 13.9 0.1 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Torsin PhoH PF02562.11 EGO55168.1 - 0.043 13.0 0.0 0.097 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EGO55168.1 - 0.045 12.6 0.0 0.076 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_21 PF13304.1 EGO55168.1 - 0.062 13.2 0.2 3.5 7.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain Guanylate_kin PF00625.16 EGO55168.1 - 0.096 12.1 0.0 0.41 10.0 0.0 2.1 1 0 0 1 1 1 0 Guanylate kinase Sigma54_activat PF00158.21 EGO55168.1 - 0.1 12.0 0.0 0.38 10.1 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 EGO55168.1 - 0.15 11.2 0.0 6.2 5.8 0.0 2.3 1 1 1 2 2 2 0 KaiC Nop PF01798.13 EGO55169.1 - 1.1e-55 187.1 0.1 1.8e-55 186.3 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGO55169.1 - 3.3e-22 78.0 0.0 1e-21 76.4 0.0 1.9 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EGO55169.1 - 4e-20 71.7 0.0 4e-20 71.7 0.0 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 EGO55169.1 - 0.097 12.3 35.6 0.18 11.4 24.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 EGO55169.1 - 0.24 11.3 13.8 0.41 10.5 9.5 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family PcfK PF14058.1 EGO55169.1 - 0.82 9.8 21.5 0.023 14.8 10.0 1.9 1 1 1 2 2 2 0 PcfK-like protein zf-met PF12874.2 EGO55170.1 - 0.0091 16.1 10.3 0.061 13.5 0.3 4.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EGO55170.1 - 0.08 13.3 26.7 0.64 10.4 1.0 5.4 4 1 1 5 5 5 0 C2H2-type zinc finger NmrA PF05368.8 EGO55171.1 - 7e-32 110.5 0.0 8.6e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO55171.1 - 1.8e-18 67.1 0.1 3.6e-17 62.9 0.1 2.1 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGO55171.1 - 7e-08 32.1 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO55171.1 - 3.7e-06 25.8 0.0 1.1e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EGO55171.1 - 0.001 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 EGO55171.1 - 0.0021 18.4 0.0 0.007 16.7 0.0 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EGO55171.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 EGO55171.1 - 0.021 15.1 0.8 0.082 13.2 0.2 2.3 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EGO55171.1 - 0.079 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.7 EGO55171.1 - 0.1 11.5 1.2 1.1 8.1 0.2 2.2 2 0 0 2 2 2 0 Male sterility protein ABC_tran PF00005.22 EGO55172.1 - 4.5e-27 95.0 0.0 1.1e-26 93.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 EGO55172.1 - 8.8e-14 51.1 5.0 1.4e-13 50.4 3.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter DUF258 PF03193.11 EGO55172.1 - 5.1e-05 22.5 0.2 9.4e-05 21.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EGO55172.1 - 0.00028 20.9 0.1 0.012 15.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGO55172.1 - 0.011 15.1 0.0 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EGO55172.1 - 0.014 14.9 1.5 0.031 13.8 1.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 EGO55172.1 - 0.026 14.3 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Dynamin family FtsK_SpoIIIE PF01580.13 EGO55172.1 - 0.036 13.5 0.2 0.076 12.4 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EGO55172.1 - 0.048 13.6 0.1 0.15 11.9 0.1 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase IIGP PF05049.8 EGO55172.1 - 0.06 12.1 0.3 0.095 11.4 0.2 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) SbcCD_C PF13558.1 EGO55172.1 - 0.081 12.8 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Septin PF00735.13 EGO55172.1 - 0.3 10.0 0.2 0.53 9.2 0.1 1.3 1 0 0 1 1 1 0 Septin ABC2_membrane_4 PF12730.2 EGO55172.1 - 0.37 9.9 6.2 0.8 8.8 4.3 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_10 PF12846.2 EGO55172.1 - 0.49 9.7 1.8 1.3 8.4 1.3 1.7 1 1 1 2 2 2 0 AAA-like domain TILa PF12714.2 EGO55172.1 - 0.73 9.6 9.3 0.44 10.3 1.6 2.7 2 0 0 2 2 2 0 TILa domain CorA PF01544.13 EGO55173.1 - 0.0032 16.5 0.3 0.0032 16.5 0.2 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein zf-GRF PF06839.7 EGO55174.1 - 0.076 12.9 4.6 0.17 11.8 3.2 1.6 1 0 0 1 1 1 0 GRF zinc finger EF-hand_1 PF00036.27 EGO55175.1 - 3.6e-35 116.5 13.7 2.1e-09 35.9 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGO55175.1 - 5e-34 116.2 6.6 2.3e-18 66.0 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGO55175.1 - 1.4e-29 99.2 8.4 5.3e-09 35.2 0.0 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EGO55175.1 - 4.6e-27 93.4 7.9 1.8e-12 46.6 0.1 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EGO55175.1 - 1.7e-25 87.1 11.0 2.9e-07 29.5 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EGO55175.1 - 8.4e-16 57.6 0.2 4.2e-07 29.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EGO55175.1 - 9.7e-10 38.1 3.5 0.00045 19.9 0.2 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EGO55175.1 - 1.2e-06 28.5 0.2 0.016 15.1 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 EGO55175.1 - 0.0002 21.0 0.5 0.21 11.2 0.0 2.4 2 1 0 2 2 2 2 Tellurite resistance protein TerB UPF0154 PF03672.8 EGO55175.1 - 0.0016 17.9 0.0 1.1 8.8 0.0 2.6 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0154) Toprim_2 PF13155.1 EGO55175.1 - 0.0044 17.2 0.8 2.5 8.4 0.1 2.3 1 1 0 2 2 2 2 Toprim-like EFhand_Ca_insen PF08726.5 EGO55175.1 - 0.009 15.9 0.3 0.019 14.9 0.2 1.6 1 0 0 1 1 1 1 Ca2+ insensitive EF hand GTPase_Cys_C PF12631.2 EGO55175.1 - 0.019 15.3 0.4 1.5 9.2 0.1 2.4 1 1 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE DUF3164 PF11363.3 EGO55175.1 - 0.028 13.7 0.4 0.45 9.8 0.0 2.4 1 1 1 3 3 3 0 Protein of unknown function (DUF3164) EF-hand_10 PF14788.1 EGO55175.1 - 0.037 13.6 2.6 0.2 11.3 0.1 3.0 2 2 2 4 4 4 0 EF hand ASL_C PF08328.6 EGO55175.1 - 0.096 12.5 0.1 0.34 10.7 0.0 1.7 1 1 1 2 2 2 0 Adenylosuccinate lyase C-terminal Peptidase_C65 PF10275.4 EGO55175.1 - 0.099 11.9 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Peptidase C65 Otubain Peptidase_S8 PF00082.17 EGO55176.1 - 2.1e-47 161.6 4.8 3.3e-47 160.9 3.3 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGO55176.1 - 2.7e-08 34.2 0.0 5.7e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 GCFC PF07842.7 EGO55177.1 - 6.5e-85 284.8 4.8 6.5e-85 284.8 3.3 1.6 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 EGO55177.1 - 1.7e-16 60.2 15.4 1.7e-16 60.2 10.7 3.5 3 1 2 5 5 5 1 Tuftelin interacting protein N terminal G-patch PF01585.18 EGO55177.1 - 5.4e-14 51.6 5.3 6.6e-14 51.4 2.1 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EGO55177.1 - 5.4e-07 29.3 2.2 5.4e-07 29.3 1.5 4.5 4 1 1 5 5 5 1 DExH-box splicing factor binding site FUSC PF04632.7 EGO55177.1 - 0.2 10.0 1.5 0.33 9.3 1.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Epimerase PF01370.16 EGO55178.1 - 5.4e-16 58.7 0.0 7.9e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO55178.1 - 2.8e-14 53.5 0.1 1.1e-13 51.6 0.1 2.0 2 1 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGO55178.1 - 4.2e-11 42.0 0.0 6.9e-11 41.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EGO55178.1 - 1.3e-10 41.4 0.8 2.4e-10 40.5 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EGO55178.1 - 3e-09 36.1 0.1 9.1e-09 34.6 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EGO55178.1 - 8.3e-06 25.5 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EGO55178.1 - 6.5e-05 22.3 0.1 0.002 17.4 0.0 2.4 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EGO55178.1 - 0.0016 17.3 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF3388 PF11868.3 EGO55181.1 - 0.077 12.1 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) ThiS-like PF14453.1 EGO55182.1 - 0.059 13.2 0.9 0.059 13.2 0.6 2.3 2 1 1 3 3 3 0 ThiS-like ubiquitin DUF2341 PF10102.4 EGO55183.1 - 0.036 14.2 0.4 0.058 13.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) DUF4366 PF14283.1 EGO55187.1 - 0.96 8.8 5.6 2.2 7.6 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Lipoprotein_20 PF13942.1 EGO55188.1 - 0.022 14.3 0.4 0.033 13.7 0.3 1.2 1 0 0 1 1 1 0 YfhG lipoprotein MinE PF03776.9 EGO55189.1 - 0.068 12.6 0.1 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE Polysacc_deac_1 PF01522.16 EGO55191.1 - 1.7e-29 101.9 0.0 8.3e-29 99.7 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGO55191.1 - 7.3e-05 21.8 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 MFS_1 PF07690.11 EGO55193.1 - 8.5e-35 120.0 39.2 1.5e-34 119.2 27.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TMEM169 PF15052.1 EGO55193.1 - 0.022 14.6 0.5 0.022 14.6 0.4 3.1 3 0 0 3 3 3 0 TMEM169 protein family adh_short PF00106.20 EGO55194.1 - 3.5e-09 36.7 0.1 1e-08 35.3 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO55194.1 - 0.0033 17.1 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF4635 PF15466.1 EGO55196.1 - 0.005 16.1 6.0 0.058 12.6 1.7 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4635) PilJ PF13675.1 EGO55196.1 - 0.013 15.8 1.5 0.024 14.9 0.4 1.9 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term CK2S PF15011.1 EGO55196.1 - 0.065 13.0 0.3 0.065 13.0 0.2 1.9 2 0 0 2 2 2 0 Casein Kinase 2 substrate IncA PF04156.9 EGO55196.1 - 3.3 7.2 13.2 0.84 9.1 4.0 2.3 1 1 1 2 2 2 0 IncA protein TMF_DNA_bd PF12329.3 EGO55196.1 - 3.7 7.4 8.5 7.1 6.5 1.1 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding F-box-like PF12937.2 EGO55197.1 - 0.033 13.9 0.1 0.069 12.8 0.1 1.5 1 0 0 1 1 1 0 F-box-like Nop14 PF04147.7 EGO55197.1 - 0.64 7.8 3.0 0.83 7.4 2.1 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C2H2 PF00096.21 EGO55198.1 - 7.5e-10 38.5 4.7 0.00026 21.1 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO55198.1 - 9.6e-09 34.9 4.0 0.0013 18.8 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGO55198.1 - 3.5e-07 30.1 7.6 4.1e-07 29.9 0.8 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EGO55198.1 - 0.058 13.5 0.0 0.4 10.8 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EGO55198.1 - 0.09 12.4 1.0 0.16 11.6 0.7 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type DUF1777 PF08648.7 EGO55198.1 - 3.1 7.5 28.6 0.51 10.0 15.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) DUF508 PF04370.7 EGO55198.1 - 4.3 6.9 7.4 17 5.0 5.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF508) COesterase PF00135.23 EGO55199.1 - 7.1e-94 315.4 0.0 9.9e-94 314.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO55199.1 - 0.00027 20.5 0.7 0.0027 17.3 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO55199.1 - 0.0057 15.8 0.1 0.031 13.4 0.4 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family PRP38 PF03371.10 EGO55200.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 PRP38 family Mit_KHE1 PF10173.4 EGO55201.1 - 0.064 13.0 0.3 8.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related P21-Arc PF04062.9 EGO55202.1 - 1.5e-79 265.8 0.0 1.7e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.8 EGO55203.1 - 4.7e-73 245.9 0.0 8.2e-73 245.1 0.0 1.5 1 1 0 1 1 1 1 Gcd10p family RP-C_C PF11800.3 EGO55203.1 - 0.26 10.9 3.7 0.57 9.8 2.6 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region YqfQ PF14181.1 EGO55203.1 - 0.47 10.4 6.9 0.97 9.4 4.8 1.5 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.9 EGO55203.1 - 2.7 5.8 9.5 5 5.0 6.6 1.3 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 EGO55203.1 - 9.6 5.1 7.9 17 4.2 5.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit GST_N_2 PF13409.1 EGO55204.1 - 4e-14 52.3 0.0 7.4e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO55204.1 - 0.052 13.4 0.0 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Fasciclin PF02469.17 EGO55206.1 - 4.6e-19 68.6 2.0 1.1e-18 67.4 0.1 2.4 3 0 0 3 3 3 1 Fasciclin domain Inositol_P PF00459.20 EGO55207.1 - 2.1e-29 102.6 0.0 4.6e-29 101.5 0.0 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family CorA PF01544.13 EGO55208.1 - 1.5e-08 34.0 0.1 1.5e-08 34.0 0.1 2.5 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein HrpB2 PF09487.5 EGO55208.1 - 0.09 12.9 0.1 0.4 10.8 0.0 2.1 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) p450 PF00067.17 EGO55209.1 - 2.2e-32 112.2 0.0 8.7e-32 110.2 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGO55210.1 - 0.00076 18.1 0.0 0.00097 17.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.19 EGO55212.1 - 3.9e-06 26.7 0.0 7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGO55212.1 - 0.0001 22.4 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGO55212.1 - 0.00099 19.2 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO55212.1 - 0.0088 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EGO55212.1 - 0.086 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 EGO55212.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 PHO4 PF01384.15 EGO55213.1 - 1.6e-108 362.2 20.8 1.9e-108 361.9 14.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family Glycos_transf_1 PF00534.15 EGO55215.1 - 5.1e-23 81.3 0.0 1.6e-22 79.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGO55215.1 - 9.5e-10 38.7 0.0 2.2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EGO55215.1 - 0.0016 18.7 0.0 0.0072 16.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Haem_bd PF14376.1 EGO55215.1 - 0.077 12.6 0.2 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Haem-binding domain Thymidylat_synt PF00303.14 EGO55216.1 - 1.5e-116 388.1 0.0 1.8e-116 387.8 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase FAD_binding_6 PF00970.19 EGO55218.1 - 1.1e-09 38.2 0.1 2.7e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Globin PF00042.17 EGO55218.1 - 3.1e-09 37.1 0.0 4.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 EGO55218.1 - 2.1e-08 34.6 0.0 5.1e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.3 EGO55218.1 - 3.6e-07 29.9 0.1 5.8e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.7 EGO55218.1 - 0.0065 16.3 0.0 0.068 13.0 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Lin-8 PF03353.10 EGO55218.1 - 0.067 12.4 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ketoacyl-synt PF00109.21 EGO55220.1 - 1.1e-79 267.4 0.0 2.2e-79 266.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGO55220.1 - 2.7e-50 171.5 0.1 5.6e-50 170.4 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EGO55220.1 - 6.6e-48 162.7 0.0 1.9e-47 161.2 0.0 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGO55220.1 - 2.5e-40 138.1 0.0 1.6e-39 135.4 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EGO55220.1 - 1.6e-38 132.6 0.0 3.7e-38 131.3 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EGO55220.1 - 2.4e-29 101.5 1.0 1.1e-28 99.4 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_23 PF13489.1 EGO55220.1 - 1.9e-05 24.4 0.0 0.00067 19.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EGO55220.1 - 4.6e-05 23.5 0.0 0.00017 21.7 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGO55220.1 - 0.003 16.5 0.0 0.0067 15.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 EGO55220.1 - 0.015 15.8 0.0 0.12 12.9 0.0 2.7 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EGO55220.1 - 0.088 12.3 0.0 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Aldose_epim PF01263.15 EGO55221.1 - 1.8e-50 171.7 0.1 2.3e-50 171.4 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase OPT PF03169.10 EGO55222.1 - 2.2e-174 581.3 48.7 2.5e-174 581.1 33.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3405 PF11885.3 EGO55223.1 - 3.5e-158 526.9 5.5 4.1e-158 526.6 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DIM1 PF02966.11 EGO55224.1 - 1.4e-68 228.5 0.4 1.5e-68 228.3 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 EGO55224.1 - 0.038 14.1 0.1 0.053 13.6 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.15 EGO55224.1 - 0.07 12.8 0.0 0.089 12.4 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Glyco_hydro_18 PF00704.23 EGO55225.1 - 1.6e-09 37.6 0.0 3.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 FAD_binding_3 PF01494.14 EGO55226.1 - 8.8e-13 48.0 3.4 1.7e-06 27.3 0.1 3.3 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EGO55226.1 - 0.034 14.1 0.6 0.13 12.2 0.4 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO55226.1 - 1.6 8.5 4.2 14 5.5 1.8 2.7 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO55227.1 - 2.4e-18 66.9 0.0 3.1e-17 63.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGO55227.1 - 1e-13 50.4 0.1 7.7e-11 40.8 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EGO55227.1 - 5.6e-09 35.3 0.0 1.2e-06 27.6 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGO55227.1 - 5.8e-09 36.1 0.0 1.6e-06 28.1 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO55227.1 - 1.8e-05 24.6 0.0 0.00011 22.1 0.0 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EGO55227.1 - 0.00058 19.0 0.0 0.0012 17.9 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EGO55227.1 - 0.013 15.9 0.0 11 6.4 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO55227.1 - 0.02 13.9 0.0 0.069 12.2 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EGO55227.1 - 0.026 13.0 0.1 0.12 10.8 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EGO55227.1 - 0.029 13.4 0.0 0.31 10.1 0.0 2.2 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EGO55227.1 - 0.041 12.7 0.0 0.11 11.2 0.0 1.7 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 EGO55227.1 - 0.053 12.4 0.1 0.63 8.8 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EGO55227.1 - 0.07 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EGO55227.1 - 0.18 10.7 0.1 0.38 9.6 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein VSP PF03302.8 EGO55228.1 - 0.0046 15.6 0.6 0.0067 15.1 0.4 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF1183 PF06682.7 EGO55228.1 - 0.0079 15.8 0.5 0.0079 15.8 0.4 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1183) K_channel_TID PF07941.6 EGO55228.1 - 0.027 14.6 5.2 0.027 14.6 3.6 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF2079 PF09852.4 EGO55228.1 - 0.15 10.7 0.2 0.22 10.1 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) DUF347 PF03988.7 EGO55228.1 - 2 8.3 8.7 1.6 8.6 0.6 2.6 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) FixQ PF05545.6 EGO55228.1 - 8.1 6.1 6.4 0.44 10.2 0.5 1.9 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Dicty_CAR PF05462.6 EGO55229.1 - 6.4e-13 48.2 6.5 6.4e-13 48.2 4.5 2.4 2 1 1 3 3 3 2 Slime mold cyclic AMP receptor Git3 PF11710.3 EGO55229.1 - 1.4e-10 41.0 7.6 2.6e-10 40.1 5.2 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EGO55229.1 - 1.7e-07 30.6 2.2 2.8e-07 29.9 1.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Tox-GHH PF15636.1 EGO55231.1 - 0.017 14.7 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Glyco_transf_36 PF06165.6 EGO55232.1 - 6.8e-20 70.9 0.0 1.3e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 36 GT36_AF PF06205.6 EGO55232.1 - 5.5e-08 32.4 0.0 1.4e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase 36 associated family DUF608 PF04685.8 EGO55232.1 - 0.001 17.8 0.1 0.0017 17.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Bac_rhamnosid PF05592.6 EGO55232.1 - 0.0066 14.7 0.0 0.012 13.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Sigma70_r1_2 PF00140.15 EGO55232.1 - 0.027 14.1 0.1 3.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 Beta_helix PF13229.1 EGO55233.1 - 1.4e-08 34.6 21.6 3.2e-07 30.2 14.2 2.5 1 1 0 1 1 1 1 Right handed beta helix region B_lectin PF01453.19 EGO55233.1 - 6.9e-06 25.9 0.3 2.1e-05 24.3 0.2 1.8 1 0 0 1 1 1 1 D-mannose binding lectin PPDK_N PF01326.14 EGO55233.1 - 0.052 12.5 0.2 0.082 11.9 0.1 1.2 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Phospholip_A2_3 PF09056.6 EGO55234.1 - 7.6e-37 125.9 1.3 1.2e-36 125.2 0.9 1.3 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 MgtE_N PF03448.12 EGO55234.1 - 0.06 13.6 0.4 0.09 13.0 0.3 1.2 1 0 0 1 1 1 0 MgtE intracellular N domain Herpes_gE PF02480.11 EGO55235.1 - 0.00022 19.6 0.2 0.32 9.1 0.0 2.1 2 0 0 2 2 2 2 Alphaherpesvirus glycoprotein E Glycophorin_A PF01102.13 EGO55235.1 - 0.0058 16.3 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 Glycophorin A Zip PF02535.17 EGO55235.1 - 0.05 12.5 0.1 0.063 12.2 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Adeno_E3_CR2 PF02439.10 EGO55235.1 - 0.1 12.1 0.1 0.28 10.7 0.1 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 HSP20 PF00011.16 EGO55237.1 - 1.1e-13 50.8 0.2 2e-08 34.0 0.1 2.4 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Paf1 PF03985.8 EGO55237.1 - 0.19 10.4 2.8 0.25 10.0 1.9 1.1 1 0 0 1 1 1 0 Paf1 p450 PF00067.17 EGO55238.1 - 6.6e-70 235.9 0.0 8.2e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ank_3 PF13606.1 EGO55240.1 - 4.2e-06 26.4 0.0 0.0085 16.2 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGO55240.1 - 8.8e-06 26.0 0.0 0.24 11.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO55240.1 - 1.3e-05 25.4 0.0 0.098 13.0 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGO55240.1 - 3.8e-05 23.2 0.0 0.027 14.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EGO55240.1 - 0.0019 18.3 0.0 0.37 11.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) MoCF_biosynth PF00994.19 EGO55241.1 - 7.7e-26 90.2 0.0 1.3e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_N PF03453.12 EGO55241.1 - 4.1e-25 88.0 0.1 1.7e-24 86.0 0.1 2.0 1 1 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EGO55241.1 - 2.2e-05 24.3 0.0 0.00064 19.6 0.0 2.6 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) CesA PF11439.3 EGO55241.1 - 0.19 11.6 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA Lipase_GDSL PF00657.17 EGO55242.1 - 1.5e-11 44.6 0.1 2e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CBM_1 PF00734.13 EGO55242.1 - 1.3e-09 37.5 8.0 1.3e-09 37.5 5.6 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.1 EGO55242.1 - 9.9e-05 22.5 0.2 0.00014 22.0 0.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family YecR PF13992.1 EGO55242.1 - 0.13 12.4 6.2 6.7 6.9 3.2 2.4 2 0 0 2 2 2 0 YecR-like lipoprotein RGS PF00615.14 EGO55244.1 - 2.4e-05 24.4 0.0 0.0021 18.1 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF4605 PF15378.1 EGO55245.1 - 0.36 10.5 3.5 0.31 10.7 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) 2OG-FeII_Oxy PF03171.15 EGO55246.1 - 0.0019 18.4 0.1 0.0048 17.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EGO55246.1 - 0.012 16.1 0.1 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF4328 PF14219.1 EGO55247.1 - 0.056 12.7 0.2 0.12 11.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) MFS_1 PF07690.11 EGO55248.1 - 5.5e-14 51.6 31.8 9.2e-10 37.7 7.4 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4191 PF13829.1 EGO55248.1 - 1.4 7.9 3.7 1.2 8.2 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) PBP1_TM PF14812.1 EGO55248.1 - 2.5 8.4 0.0 2.5 8.4 0.0 3.5 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Abhydrolase_3 PF07859.8 EGO55249.1 - 4.2e-58 196.3 0.4 5.2e-58 196.0 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGO55249.1 - 6e-08 32.8 3.9 1.1e-07 31.9 2.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO55249.1 - 2.1e-07 30.3 0.0 3.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO55249.1 - 1.8e-06 27.8 0.1 2.6e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EGO55249.1 - 0.00042 19.1 0.6 0.0024 16.6 0.4 1.8 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.13 EGO55249.1 - 0.0008 18.7 0.0 0.0068 15.7 0.0 2.2 3 0 0 3 3 3 1 Dienelactone hydrolase family AXE1 PF05448.7 EGO55249.1 - 0.0066 14.9 0.0 0.0098 14.4 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 EGO55249.1 - 0.023 13.9 0.1 0.049 12.8 0.1 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydro_lipase PF04083.11 EGO55249.1 - 0.031 13.6 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 EGO55250.1 - 0.0013 18.5 0.0 0.0057 16.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3336 PF11815.3 EGO55251.1 - 3.2e-42 143.4 0.2 6.9e-42 142.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EGO55251.1 - 8.9e-23 81.2 0.0 1.7e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase LEA_3 PF03242.8 EGO55251.1 - 0.034 14.3 0.7 0.48 10.6 0.0 2.6 2 0 0 2 2 2 0 Late embryogenesis abundant protein GreA_GreB_N PF03449.10 EGO55251.1 - 0.58 10.2 3.0 2.7 8.0 0.2 2.7 2 1 0 2 2 2 0 Transcription elongation factor, N-terminal Cu_amine_oxid PF01179.15 EGO55253.1 - 9.1e-123 410.0 5.2 1.1e-122 409.7 3.6 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EGO55253.1 - 2.1e-39 133.2 0.1 5.7e-39 131.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EGO55253.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain FA_hydroxylase PF04116.8 EGO55256.1 - 7.5e-19 68.2 13.7 7.5e-19 68.2 9.5 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily NmrA PF05368.8 EGO55258.1 - 5.6e-33 114.1 0.0 6.8e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO55258.1 - 7.5e-12 45.6 0.0 1e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO55258.1 - 0.00075 19.0 0.0 0.0016 17.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EGO55258.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.7 EGO55258.1 - 0.073 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein KR PF08659.5 EGO55258.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 EGO55258.1 - 0.12 11.1 0.0 0.25 10.0 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Beta-lactamase PF00144.19 EGO55259.1 - 2e-39 135.5 0.0 4.8e-39 134.2 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.1 EGO55259.1 - 0.028 13.8 0.0 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Beta-lactamase enzyme family DUF3368 PF11848.3 EGO55259.1 - 0.05 13.1 0.1 4.6 6.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) Peptidase_S11 PF00768.15 EGO55259.1 - 0.052 12.8 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Hormone_1 PF00103.15 EGO55260.1 - 0.017 14.4 0.6 0.043 13.1 0.4 1.6 1 0 0 1 1 1 0 Somatotropin hormone family Sporozoite_P67 PF05642.6 EGO55260.1 - 0.85 7.4 6.0 1.3 6.7 4.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Lyase_aromatic PF00221.14 EGO55267.1 - 2.2e-159 530.9 4.5 2.7e-159 530.6 3.1 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase adh_short PF00106.20 EGO55268.1 - 9.3e-30 103.7 0.2 1.4e-29 103.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO55268.1 - 3.2e-28 99.1 0.0 4.9e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO55268.1 - 1.9e-15 56.9 0.1 3e-15 56.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO55268.1 - 0.0036 16.7 0.3 0.0072 15.7 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EGO55268.1 - 0.0046 16.4 2.4 0.54 9.8 1.7 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase B12-binding PF02310.14 EGO55268.1 - 0.007 16.2 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 B12 binding domain Polysacc_synt_2 PF02719.10 EGO55268.1 - 0.023 13.6 0.5 0.036 12.9 0.3 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGO55268.1 - 0.027 14.4 0.4 0.068 13.1 0.2 1.7 2 0 0 2 2 2 0 NADH(P)-binding DUF1372 PF07116.6 EGO55268.1 - 0.038 13.9 0.0 0.093 12.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1372) Bac_luciferase PF00296.15 EGO55270.1 - 4.7e-61 206.5 0.0 6.1e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Acyl-CoA_dh_2 PF08028.6 EGO55271.1 - 2.5e-15 56.9 2.3 5.8e-15 55.7 1.6 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGO55271.1 - 6.1e-08 33.2 0.1 1.1e-07 32.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EGO55271.1 - 4.4e-05 23.6 2.5 0.00014 22.0 0.0 2.7 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGO55271.1 - 0.1 12.1 0.0 0.38 10.3 0.0 1.9 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain SAPS PF04499.10 EGO55273.1 - 2e-195 649.9 0.0 9.9e-195 647.6 0.0 2.1 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein DUF4386 PF14329.1 EGO55274.1 - 0.00036 20.0 6.6 0.00036 20.0 4.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4386) DUF3593 PF12159.3 EGO55274.1 - 0.043 13.5 0.2 0.043 13.5 0.1 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3593) DUF1624 PF07786.7 EGO55274.1 - 0.4 9.9 6.6 0.56 9.4 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1624) DUF4149 PF13664.1 EGO55274.1 - 1.8 8.7 6.1 9.2 6.3 3.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) Meth_synt_2 PF01717.13 EGO55275.1 - 4.3e-20 71.9 0.0 6.5e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EGO55275.1 - 3.9e-06 26.3 0.0 0.064 12.5 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Sugar_tr PF00083.19 EGO55276.1 - 1.6e-115 386.2 33.8 1.8e-115 386.0 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO55276.1 - 3.4e-24 85.2 37.0 1.7e-20 73.0 20.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGO55276.1 - 1.5e-09 36.7 30.2 3.4e-05 22.4 10.2 3.4 3 1 0 3 3 3 3 MFS/sugar transport protein Bac_rhodopsin PF01036.13 EGO55279.1 - 5.2e-47 160.0 15.7 6.3e-47 159.7 10.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DuoxA PF10204.4 EGO55279.1 - 0.0062 15.6 2.6 0.0062 15.6 1.8 2.2 1 1 2 3 3 3 1 Dual oxidase maturation factor zf-C3HC4 PF00097.20 EGO55283.1 - 4.5e-05 23.0 4.5 9e-05 22.0 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO55283.1 - 0.0019 18.0 4.9 0.0028 17.4 3.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO55283.1 - 0.0067 16.4 7.4 0.011 15.7 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO55283.1 - 0.008 15.8 6.4 0.012 15.3 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ribosomal_L40e PF01020.12 EGO55283.1 - 0.022 14.3 0.4 0.036 13.6 0.3 1.4 1 0 0 1 1 1 0 Ribosomal L40e family Fer2 PF00111.22 EGO55283.1 - 0.25 11.1 2.4 0.38 10.5 1.7 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF4428 PF14471.1 EGO55283.1 - 0.4 10.4 7.1 0.87 9.3 4.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) zf-RING_5 PF14634.1 EGO55283.1 - 1.5 8.6 7.2 3 7.6 5.0 1.6 1 1 0 1 1 1 0 zinc-RING finger domain Shugoshin_C PF07557.6 EGO55284.1 - 0.029 13.8 0.3 0.029 13.8 0.2 3.2 4 0 0 4 4 4 0 Shugoshin C terminus Adaptin_N PF01602.15 EGO55285.1 - 2.2e-150 501.4 2.4 3.1e-150 500.9 1.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EGO55285.1 - 2.7e-26 92.4 0.3 3.1e-25 89.0 0.0 2.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EGO55285.1 - 5.8e-18 64.9 0.1 1e-06 28.8 0.0 5.2 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EGO55285.1 - 1.9e-11 43.0 2.8 0.016 15.2 0.0 6.2 7 0 0 7 7 6 3 HEAT repeat HEAT_EZ PF13513.1 EGO55285.1 - 5.4e-05 23.5 0.4 4.5 7.8 0.0 5.6 5 1 1 6 6 6 1 HEAT-like repeat UNC45-central PF11701.3 EGO55285.1 - 0.00037 20.1 0.0 0.24 11.0 0.1 2.6 2 1 0 2 2 2 2 Myosin-binding striated muscle assembly central Arm PF00514.18 EGO55285.1 - 0.0044 16.8 0.6 16 5.5 0.0 5.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 EGO55285.1 - 0.0083 15.8 0.0 0.17 11.6 0.0 2.8 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 EGO55285.1 - 0.024 13.9 0.2 2.8 7.2 0.0 3.4 3 1 1 4 4 4 0 CLASP N terminal Cohesin_HEAT PF12765.2 EGO55285.1 - 0.11 12.5 0.1 59 3.7 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion AF0941-like PF14591.1 EGO55285.1 - 0.11 12.5 1.1 0.49 10.4 0.8 2.1 1 0 0 1 1 1 0 AF0941-like Utp12 PF04003.7 EGO55285.1 - 0.15 12.0 1.5 2.1 8.2 0.1 3.0 2 1 0 2 2 2 0 Dip2/Utp12 Family Cerato-platanin PF07249.7 EGO55286.1 - 0.00054 19.9 0.1 0.00091 19.2 0.1 1.4 1 0 0 1 1 1 1 Cerato-platanin Asparaginase_2 PF01112.13 EGO55287.1 - 6.3e-52 176.2 0.1 9.5e-52 175.6 0.0 1.2 1 0 0 1 1 1 1 Asparaginase MatE PF01554.13 EGO55288.1 - 6.2e-09 35.6 18.2 0.00019 21.0 2.2 4.4 4 1 0 4 4 4 3 MatE Med3 PF11593.3 EGO55289.1 - 0.17 11.0 6.0 0.23 10.6 4.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glyco_transf_20 PF00982.16 EGO55290.1 - 6.1e-197 654.7 0.0 7.1e-197 654.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EGO55290.1 - 0.07 12.6 0.1 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain DUF2945 PF11160.3 EGO55291.1 - 0.068 13.0 2.0 0.28 11.0 1.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2945) VID27 PF08553.5 EGO55294.1 - 0 1200.9 0.0 0 1200.8 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Prenylcys_lyase PF07156.9 EGO55295.1 - 3.6e-31 108.3 0.0 2.9e-30 105.4 0.0 1.9 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EGO55295.1 - 1.3e-13 50.7 0.7 3.5e-13 49.3 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGO55295.1 - 3.3e-06 26.9 0.2 1.6e-05 24.7 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EGO55295.1 - 2.4e-05 23.6 0.0 0.00011 21.4 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EGO55295.1 - 6.9e-05 21.9 0.0 0.00028 19.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO55295.1 - 0.00013 22.1 0.0 0.016 15.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO55295.1 - 0.00023 21.1 0.3 0.0041 17.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO55295.1 - 0.0071 15.4 2.1 0.012 14.7 0.0 2.2 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.15 EGO55295.1 - 0.014 15.5 0.0 0.048 13.7 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EGO55295.1 - 0.025 13.4 0.3 0.04 12.7 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EGO55295.1 - 0.034 14.5 0.1 2.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGO55295.1 - 0.058 12.0 0.1 0.18 10.3 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.16 EGO55295.1 - 0.06 12.9 0.1 0.78 9.2 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EGO55295.1 - 0.084 11.3 0.1 0.19 10.1 0.0 1.6 1 0 0 1 1 1 0 HI0933-like protein Cpn60_TCP1 PF00118.19 EGO55296.1 - 1.1e-149 499.2 0.1 1.2e-149 499.0 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PDCD2_C PF04194.8 EGO55297.1 - 1.4e-56 190.6 0.0 1.4e-56 190.6 0.0 3.1 4 0 0 4 4 4 1 Programmed cell death protein 2, C-terminal putative domain Pex16 PF08610.5 EGO55297.1 - 8.4 5.2 8.0 16 4.4 5.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) PCI_Csn8 PF10075.4 EGO55298.1 - 3.3e-39 133.9 0.0 4.7e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EGO55298.1 - 1.7e-23 83.2 0.0 2.4e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DNA_ligase_A_M PF01068.16 EGO55299.1 - 4.1e-48 163.4 0.1 1.3e-45 155.2 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGO55299.1 - 1.7e-32 112.6 0.0 3.3e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGO55299.1 - 2e-19 69.7 0.1 1.8e-18 66.7 0.0 2.7 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region Aldose_epim PF01263.15 EGO55300.1 - 8.8e-59 199.0 0.0 1.4e-58 198.3 0.0 1.3 1 1 0 1 1 1 1 Aldose 1-epimerase RTC PF01137.16 EGO55301.1 - 4.9e-05 22.2 0.0 0.0005 18.9 0.0 2.0 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase AAL_decarboxy PF03306.8 EGO55302.1 - 1.4e-76 256.3 0.2 1.6e-76 256.1 0.2 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase Glyco_hydr_30_2 PF14587.1 EGO55303.1 - 3.2e-15 55.9 5.5 7.4e-15 54.7 3.8 1.6 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 AMP-binding PF00501.23 EGO55304.1 - 4.3e-42 143.9 0.3 2.2e-41 141.6 0.2 2.0 1 1 0 1 1 1 1 AMP-binding enzyme Spc7 PF08317.6 EGO55304.1 - 0.01 14.5 0.7 0.017 13.8 0.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3782 PF12644.2 EGO55304.1 - 0.15 11.8 0.1 0.37 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Cpn60_TCP1 PF00118.19 EGO55305.1 - 1.5e-142 475.6 4.8 1.8e-142 475.4 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Acetyltransf_1 PF00583.19 EGO55306.1 - 0.00075 19.4 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EGO55306.1 - 0.0021 18.0 0.0 0.0034 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGO55306.1 - 0.006 16.7 0.0 0.0082 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CBS PF00571.23 EGO55307.1 - 2e-39 133.0 8.2 1.2e-09 37.7 0.0 4.8 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EGO55307.1 - 7.9e-09 35.0 0.0 1.9e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 PB1 domain DUF3235 PF11574.3 EGO55307.1 - 0.034 14.3 0.6 1.5 9.1 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Rifin_STEVOR PF02009.11 EGO55308.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Rifin/stevor family DUF4366 PF14283.1 EGO55308.1 - 0.082 12.3 1.4 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Tyrosinase PF00264.15 EGO55309.1 - 9.1e-43 146.9 0.0 1.4e-42 146.3 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Rap1_C PF11626.3 EGO55310.1 - 0.066 13.1 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ank_2 PF12796.2 EGO55311.1 - 0.0085 16.4 0.0 0.45 10.8 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGO55311.1 - 0.012 15.8 0.0 0.05 13.8 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat Ank_5 PF13857.1 EGO55311.1 - 0.034 14.3 0.1 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.25 EGO55311.1 - 0.039 13.7 0.0 0.15 11.9 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat Syntaxin-6_N PF09177.6 EGO55311.1 - 0.13 12.7 1.5 2.5 8.5 0.0 3.1 1 1 1 3 3 3 0 Syntaxin 6, N-terminal DltD_M PF04918.7 EGO55311.1 - 0.14 12.3 0.6 0.24 11.6 0.4 1.3 1 0 0 1 1 1 0 DltD central region Glyco_hydro_18 PF00704.23 EGO55314.1 - 4.8e-98 328.7 0.3 5.9e-98 328.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 EGO55314.1 - 0.029 13.5 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 ubiquitin PF00240.18 EGO55315.1 - 5.3e-35 118.6 1.3 1e-34 117.7 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EGO55315.1 - 7.7e-29 99.2 2.1 1.6e-28 98.2 1.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EGO55315.1 - 3.3e-20 71.5 1.0 6.4e-20 70.6 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGO55315.1 - 3.7e-06 27.0 0.6 1.6e-05 25.0 0.2 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGO55315.1 - 0.00011 21.9 0.1 0.00018 21.2 0.0 1.3 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EGO55315.1 - 0.00054 19.8 0.8 0.0012 18.6 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGO55315.1 - 0.0014 18.7 0.6 0.002 18.2 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EGO55315.1 - 0.064 13.2 0.2 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) IBR PF01485.16 EGO55315.1 - 0.095 12.5 0.5 0.16 11.9 0.4 1.4 1 0 0 1 1 1 0 IBR domain Plexin_cytopl PF08337.7 EGO55315.1 - 0.1 10.8 2.8 3.4 5.8 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF2207 PF09972.4 EGO55315.1 - 0.1 11.1 0.6 0.11 11.0 0.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Fer2_3 PF13085.1 EGO55315.1 - 0.21 11.4 1.1 0.5 10.2 0.8 1.9 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Ribosomal_S26e PF01283.14 EGO55316.1 - 1.6e-51 173.3 9.6 1.8e-51 173.2 6.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 EGO55316.1 - 0.019 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Zn_ribbon_2 PF12674.2 EGO55316.1 - 0.053 13.8 0.3 7.8 6.9 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_7 PF12838.2 EGO55316.1 - 0.099 13.0 2.3 1.2 9.6 0.4 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain U79_P34 PF03064.11 EGO55317.1 - 0.55 9.7 4.7 1.3 8.5 3.3 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3767 PF12597.3 EGO55318.1 - 1.4e-18 66.6 3.0 2e-18 66.1 2.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) DUF3558 PF12079.3 EGO55318.1 - 0.0029 17.2 0.7 0.0034 17.0 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3558) GFO_IDH_MocA PF01408.17 EGO55318.1 - 0.05 14.1 0.1 0.061 13.8 0.0 1.1 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold TAF4 PF05236.9 EGO55318.1 - 0.86 8.8 6.1 1.1 8.4 4.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF1744 PF08490.7 EGO55319.1 - 2.3e-162 540.0 0.0 3.3e-162 539.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EGO55319.1 - 8.3e-68 228.6 0.3 1.4e-67 227.9 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EGO55319.1 - 5.5e-21 74.8 0.3 1.7e-20 73.2 0.2 1.7 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EGO55319.1 - 1.2e-09 38.0 0.1 3e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EGO55319.1 - 1.3e-05 25.1 0.1 4.2e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 RNase_H superfamily MFS_1 PF07690.11 EGO55320.1 - 2.4e-46 158.0 55.2 1.5e-45 155.4 35.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGO55320.1 - 5.4e-14 51.3 25.7 1.7e-13 49.6 17.8 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGO55320.1 - 2.5e-09 36.2 13.7 2.5e-09 36.2 9.5 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter TFIIA PF03153.8 EGO55321.1 - 5.6 6.7 12.0 8.1 6.2 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FliH PF02108.11 EGO55322.1 - 1.8 8.4 10.8 0.33 10.8 3.0 2.9 3 1 1 4 4 4 0 Flagellar assembly protein FliH Osmo_CC PF08946.5 EGO55322.1 - 3.3 7.7 10.6 15 5.6 0.0 4.5 5 0 0 5 5 5 0 Osmosensory transporter coiled coil TMP_2 PF06791.8 EGO55322.1 - 8.1 5.9 18.3 0.31 10.6 5.7 2.7 2 1 1 3 3 3 0 Prophage tail length tape measure protein WD40 PF00400.27 EGO55326.1 - 5e-38 127.6 11.5 9.5e-07 28.4 0.2 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EGO55326.1 - 4.5e-13 48.6 2.6 5.3e-13 48.4 0.4 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGO55326.1 - 0.00016 21.2 0.0 0.00039 19.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EGO55326.1 - 0.16 10.0 0.8 4.2 5.3 0.1 2.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 FMN_dh PF01070.13 EGO55327.1 - 2.8e-100 335.6 0.1 4.1e-100 335.0 0.1 1.2 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EGO55327.1 - 5.8e-05 22.1 0.4 9.7e-05 21.4 0.3 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EGO55327.1 - 0.0061 15.8 0.3 0.14 11.3 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein Glu_synthase PF01645.12 EGO55327.1 - 0.007 15.3 0.2 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Cobl PF09469.5 EGO55328.1 - 0.16 11.9 0.1 0.43 10.5 0.1 1.7 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain Sugar_tr PF00083.19 EGO55329.1 - 1.7e-125 419.1 26.8 1.9e-125 418.9 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO55329.1 - 6.3e-22 77.7 34.3 8.3e-14 51.0 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGO55329.1 - 0.0052 15.0 0.6 0.0052 15.0 0.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Lig_chan PF00060.21 EGO55329.1 - 0.072 12.8 1.3 1 9.0 0.0 3.0 2 1 1 3 3 3 0 Ligand-gated ion channel DUF3154 PF11351.3 EGO55329.1 - 1.6 8.5 4.5 10 5.9 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3154) DUF2530 PF10745.4 EGO55329.1 - 9.2 6.3 10.4 1.1 9.2 3.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) HEAT_2 PF13646.1 EGO55330.1 - 1.1e-07 32.0 2.9 0.074 13.3 0.0 5.1 4 1 1 5 5 5 2 HEAT repeats CLASP_N PF12348.3 EGO55330.1 - 1.2e-07 31.3 0.3 2.9e-06 26.8 0.1 2.4 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.17 EGO55330.1 - 2e-07 30.5 4.9 0.58 10.3 0.1 6.3 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.15 EGO55330.1 - 0.00031 19.2 0.2 0.48 8.6 0.1 2.7 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 EGO55330.1 - 0.0006 20.2 3.8 0.88 10.1 0.0 4.8 5 0 0 5 5 3 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGO55330.1 - 0.04 14.2 0.2 0.88 10.0 0.1 3.1 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EGO55330.1 - 0.056 13.2 1.9 0.48 10.2 0.1 2.9 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 APG6 PF04111.7 EGO55330.1 - 0.07 12.1 10.8 0.14 11.1 7.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 EGO55330.1 - 0.16 11.8 12.9 0.54 10.1 9.0 1.9 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Proteasom_PSMB PF10508.4 EGO55330.1 - 0.29 9.3 6.0 0.57 8.3 0.1 3.2 3 1 1 4 4 4 0 Proteasome non-ATPase 26S subunit DUF972 PF06156.8 EGO55330.1 - 0.58 10.5 6.0 64 3.9 4.2 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 EGO55330.1 - 1 8.9 15.4 0.012 15.1 5.1 1.9 2 0 0 2 2 2 0 IncA protein NYD-SP28_assoc PF14775.1 EGO55330.1 - 6.6 6.5 7.1 1.8 8.3 1.4 2.6 2 1 1 3 3 3 0 Sperm tail C-terminal domain WD40 PF00400.27 EGO55331.1 - 1.5e-76 249.7 17.2 9e-12 44.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGO55331.1 - 2.2e-10 39.3 2.3 5.6e-05 21.4 0.1 4.1 2 2 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGO55331.1 - 6e-05 21.9 0.0 0.084 11.6 0.0 3.2 1 1 1 3 3 3 2 Nup133 N terminal like bZIP_1 PF00170.16 EGO55331.1 - 0.29 11.0 1.0 0.42 10.6 0.1 1.6 2 0 0 2 2 2 0 bZIP transcription factor Membrane_bind PF14564.1 EGO55332.1 - 2e-30 105.1 0.0 3e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Membrane binding Crystall_3 PF08964.5 EGO55332.1 - 4.5e-30 103.2 1.9 1.2e-29 101.8 0.2 2.3 3 0 0 3 3 3 1 Beta/Gamma crystallin Metallophos PF00149.23 EGO55333.1 - 0.00019 20.9 0.4 0.0014 18.1 0.1 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Condensation PF00668.15 EGO55335.1 - 2e-74 250.1 29.7 5.8e-33 114.0 0.0 5.6 4 1 1 5 5 4 4 Condensation domain AMP-binding PF00501.23 EGO55335.1 - 1.1e-33 116.2 6.8 5.6e-22 77.7 0.1 3.2 2 1 1 3 3 3 2 AMP-binding enzyme PP-binding PF00550.20 EGO55335.1 - 9e-23 80.3 0.1 3.6e-07 30.3 0.1 4.8 5 0 0 5 5 4 3 Phosphopantetheine attachment site PAT1 PF09770.4 EGO55335.1 - 0.00046 18.6 46.3 0.00074 17.9 32.1 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SprA-related PF12118.3 EGO55335.1 - 0.00098 18.5 42.9 0.002 17.4 29.7 1.5 1 0 0 1 1 1 1 SprA-related family Med15 PF09606.5 EGO55335.1 - 0.0024 16.1 66.9 0.0039 15.4 46.4 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.7 EGO55335.1 - 0.018 14.9 12.2 0.036 13.9 8.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.8 EGO55335.1 - 0.035 14.0 38.7 0.086 12.7 26.8 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ycf1 PF05758.7 EGO55335.1 - 0.042 11.5 13.2 0.064 10.9 9.1 1.1 1 0 0 1 1 1 0 Ycf1 UPF0560 PF10577.4 EGO55335.1 - 0.12 10.5 24.4 0.19 9.9 16.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Neur_chan_memb PF02932.11 EGO55335.1 - 0.18 11.6 9.1 0.4 10.5 6.3 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.7 EGO55335.1 - 0.31 9.6 24.3 0.61 8.6 16.9 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4557 PF15101.1 EGO55335.1 - 0.33 10.7 31.8 0.82 9.4 22.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FLO_LFY PF01698.11 EGO55335.1 - 0.43 9.3 15.0 0.71 8.6 10.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein FAM60A PF15396.1 EGO55335.1 - 0.78 9.4 13.3 1.8 8.2 9.2 1.5 1 0 0 1 1 1 0 Protein Family FAM60A OmpH PF03938.9 EGO55335.1 - 0.86 9.5 50.7 1.9 8.4 32.4 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Spore_coat_CotO PF14153.1 EGO55335.1 - 1.2 8.5 29.3 2.3 7.6 20.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO eIF3_subunit PF08597.5 EGO55335.1 - 1.7 8.1 19.6 3.5 7.1 13.6 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Zip PF02535.17 EGO55335.1 - 2 7.3 5.2 3.5 6.5 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter AUX_IAA PF02309.11 EGO55335.1 - 4.1 7.1 19.8 8.7 6.0 13.8 1.4 1 0 0 1 1 1 0 AUX/IAA family Hid1 PF12722.2 EGO55335.1 - 4.5 4.8 21.1 7 4.1 14.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MRP-S31 PF15433.1 EGO55335.1 - 4.9 6.4 26.3 1.4 8.2 15.2 2.0 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Paramyxo_ncap PF00973.14 EGO55335.1 - 6.6 5.2 15.4 11 4.5 10.7 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF605 PF04652.11 EGO55335.1 - 6.8 5.9 31.7 12 5.1 22.0 1.3 1 0 0 1 1 1 0 Vta1 like CDC45 PF02724.9 EGO55335.1 - 8.9 4.2 18.6 14 3.5 12.9 1.2 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.1 EGO55335.1 - 9.1 6.4 26.7 0.52 10.4 13.9 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal LMBR1 PF04791.11 EGO55335.1 - 9.1 4.7 5.7 14 4.0 3.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Cu-oxidase_3 PF07732.10 EGO55336.1 - 2.7e-41 140.0 3.2 2.7e-41 140.0 2.2 3.1 4 1 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGO55336.1 - 3.8e-39 133.3 9.1 6.5e-38 129.3 0.3 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EGO55336.1 - 2.5e-37 128.2 0.0 5.1e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase MARVEL PF01284.18 EGO55337.1 - 7.7e-09 35.5 8.1 1.3e-08 34.7 5.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF3129 PF11327.3 EGO55338.1 - 8.9e-57 191.8 11.1 1.8e-56 190.8 7.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) MYEOV2 PF15004.1 EGO55338.1 - 0.095 13.2 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Myeloma-overexpressed-like DUF1918 PF08940.6 EGO55338.1 - 0.14 11.4 0.0 1.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Diphthamide_syn PF01866.12 EGO55340.1 - 1.6e-49 168.7 0.0 2.9e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MFS_1 PF07690.11 EGO55341.1 - 3.3e-37 128.0 77.1 6.3e-30 104.0 29.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO55341.1 - 2.2e-10 39.7 38.5 2.1e-06 26.6 9.8 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 EGO55341.1 - 0.001 18.8 3.3 0.51 10.1 0.3 2.7 2 0 0 2 2 2 2 MFS_1 like family DUF4538 PF15061.1 EGO55341.1 - 2.5 7.4 4.2 0.76 9.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Glyco_transf_15 PF01793.11 EGO55342.1 - 1.4e-85 287.1 4.1 1.8e-85 286.8 2.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase zf-ribbon_3 PF13248.1 EGO55343.1 - 0.0037 16.4 4.7 0.49 9.6 0.4 2.8 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.2 EGO55343.1 - 0.074 12.8 0.6 11 5.9 0.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon Myosin_tail_1 PF01576.14 EGO55344.1 - 0.00096 17.0 21.0 0.00096 17.0 14.6 3.2 2 1 1 3 3 3 2 Myosin tail DUF4400 PF14348.1 EGO55344.1 - 8.5 5.7 4.9 2.7 7.3 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) Raptor_N PF14538.1 EGO55344.1 - 9 6.1 7.7 0.54 10.0 0.1 2.8 4 0 0 4 4 4 0 Raptor N-terminal CASPase like domain IncA PF04156.9 EGO55345.1 - 0.0006 19.4 21.4 0.009 15.6 3.9 2.6 1 1 0 2 2 2 2 IncA protein APG6 PF04111.7 EGO55345.1 - 0.00086 18.4 17.3 0.059 12.4 6.8 2.4 2 0 0 2 2 2 2 Autophagy protein Apg6 Cep57_CLD PF14073.1 EGO55345.1 - 0.0036 17.1 0.7 0.0036 17.1 0.5 3.0 3 0 0 3 3 3 1 Centrosome localisation domain of Cep57 YppF PF14178.1 EGO55345.1 - 0.0064 15.9 0.1 0.095 12.2 0.0 2.8 3 0 0 3 3 3 1 YppF-like protein DUF972 PF06156.8 EGO55345.1 - 0.0092 16.3 17.1 0.016 15.5 0.3 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF972) HR1 PF02185.11 EGO55345.1 - 0.015 15.0 1.1 0.015 15.0 0.8 3.7 4 0 0 4 4 4 0 Hr1 repeat WXG100 PF06013.7 EGO55345.1 - 0.019 14.9 8.7 1.7 8.6 0.5 4.1 5 0 0 5 5 3 0 Proteins of 100 residues with WXG TPR_MLP1_2 PF07926.7 EGO55345.1 - 0.026 14.2 26.2 0.31 10.7 0.4 3.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Snapin_Pallidin PF14712.1 EGO55345.1 - 0.03 14.6 6.8 0.52 10.6 0.9 3.0 3 0 0 3 3 2 0 Snapin/Pallidin DUF1664 PF07889.7 EGO55345.1 - 0.031 14.0 11.8 0.28 10.9 1.5 3.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Ribosomal_L10 PF00466.15 EGO55345.1 - 0.039 13.8 0.7 0.19 11.6 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L10 Occludin_ELL PF07303.8 EGO55345.1 - 0.13 12.9 13.2 0.41 11.3 0.2 3.2 3 2 0 3 3 3 0 Occludin homology domain TMCO5 PF14992.1 EGO55345.1 - 0.16 11.0 17.2 0.51 9.4 0.4 2.6 2 1 0 2 2 2 0 TMCO5 family COG2 PF06148.6 EGO55345.1 - 0.33 10.8 11.5 1.4 8.8 0.6 4.0 2 2 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 V_ATPase_I PF01496.14 EGO55345.1 - 0.41 8.4 12.1 0.042 11.7 0.8 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EGO55345.1 - 0.46 9.3 10.7 1.2 8.0 0.2 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Sec2p PF06428.6 EGO55345.1 - 0.54 10.1 13.5 0.52 10.1 1.1 3.0 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p T2SF PF00482.18 EGO55345.1 - 0.8 9.6 2.6 1.8 8.4 0.6 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Laminin_II PF06009.7 EGO55345.1 - 0.86 9.3 12.2 0.14 11.9 0.4 3.6 3 1 0 3 3 3 0 Laminin Domain II Baculo_PEP_C PF04513.7 EGO55345.1 - 0.87 9.4 9.8 1.2 8.9 0.4 3.5 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 EGO55345.1 - 0.91 9.0 24.4 0.48 9.9 2.0 4.6 2 2 3 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4201 PF13870.1 EGO55345.1 - 0.96 8.8 18.7 0.45 9.9 0.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) DivIVA PF05103.8 EGO55345.1 - 1 9.4 20.7 0.56 10.2 1.1 3.0 3 0 0 3 3 3 0 DivIVA protein DUF342 PF03961.8 EGO55345.1 - 1.8 6.8 19.1 0.11 10.8 4.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF342) Lebercilin PF15619.1 EGO55345.1 - 4.5 6.6 21.5 5.6 6.3 2.2 2.9 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF4446 PF14584.1 EGO55345.1 - 8.9 6.1 14.5 10 5.9 0.1 4.2 2 2 3 5 5 5 0 Protein of unknown function (DUF4446) Cytochrom_B562 PF07361.6 EGO55345.1 - 9 6.7 13.5 3.4 8.1 1.0 3.9 2 2 2 4 4 4 0 Cytochrome b562 TPR_MLP1_2 PF07926.7 EGO55346.1 - 8.5e-05 22.3 7.5 8.5e-05 22.3 5.2 3.1 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein FCD PF07729.7 EGO55346.1 - 0.014 15.7 3.6 0.031 14.5 2.5 1.6 1 0 0 1 1 1 0 FCD domain TIP120 PF08623.5 EGO55346.1 - 0.035 13.6 1.7 0.074 12.6 1.2 1.5 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Cytochrom_B562 PF07361.6 EGO55346.1 - 0.28 11.5 8.5 0.85 10.0 3.6 2.5 2 0 0 2 2 2 0 Cytochrome b562 Exonuc_VII_L PF02601.10 EGO55346.1 - 1.5 7.9 12.7 2.8 7.0 8.8 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit MFS_1 PF07690.11 EGO55348.1 - 2.1e-38 131.9 23.7 2.1e-38 131.9 16.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGO55348.1 - 2.7e-05 23.7 2.1 6.9e-05 22.3 1.4 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DUF2881 PF11087.3 EGO55348.1 - 0.45 10.0 4.5 1.6 8.3 2.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2881) RRN3 PF05327.6 EGO55352.1 - 1.9 6.4 11.2 2 6.4 7.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 EGO55353.1 - 1.7 6.6 4.3 1.6 6.6 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Pyr_redox_3 PF13738.1 EGO55354.1 - 2.8e-16 60.1 0.0 7e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGO55354.1 - 2.2e-11 42.6 0.0 5.1e-11 41.4 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EGO55354.1 - 1.5e-08 33.9 0.0 7.1e-05 21.8 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGO55354.1 - 1.2e-06 28.4 0.0 2.9e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GBP_PSP PF02425.10 EGO55354.1 - 0.054 13.0 0.0 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide Abhydrolase_3 PF07859.8 EGO55355.1 - 1.3e-25 90.2 0.4 1.9e-25 89.6 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGO55355.1 - 1.6e-15 56.6 0.0 2e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGO55355.1 - 1.3e-05 25.0 0.1 1.7e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family TM2 PF05154.11 EGO55357.1 - 0.00011 22.3 1.5 0.00011 22.3 1.1 2.4 3 0 0 3 3 3 1 TM2 domain DnaJ PF00226.26 EGO55358.1 - 6e-11 41.9 0.4 1.3e-10 40.8 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain RHH_2 PF03693.9 EGO55358.1 - 0.056 13.6 0.0 0.093 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0156) DEAD PF00270.24 EGO55359.1 - 1.2e-43 148.4 0.0 1.8e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO55359.1 - 1e-23 82.9 0.1 2.1e-23 81.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EspF PF04806.7 EGO55361.1 - 0.44 10.7 4.9 0.41 10.8 1.0 2.5 2 0 0 2 2 2 0 EspF protein repeat GRP PF07172.6 EGO55362.1 - 5.3 7.5 9.4 1.9 9.0 3.8 2.3 2 0 0 2 2 2 0 Glycine rich protein family TMF_DNA_bd PF12329.3 EGO55362.1 - 9.9 6.0 21.3 0.035 13.9 0.9 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding zf-C2H2 PF00096.21 EGO55363.1 - 3.2e-06 27.1 3.4 0.011 16.0 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO55363.1 - 0.0006 19.9 4.1 0.022 15.0 0.0 2.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO55363.1 - 0.0068 16.5 2.1 2.9 8.1 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding LIM PF00412.17 EGO55363.1 - 0.075 13.1 0.6 0.16 12.0 0.4 1.5 1 1 0 1 1 1 0 LIM domain zf-Di19 PF05605.7 EGO55363.1 - 0.079 13.0 1.1 3.5 7.8 0.2 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EGO55363.1 - 0.12 12.3 3.1 3.9 7.4 0.0 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger Kinesin PF00225.18 EGO55364.1 - 2.6e-114 381.4 0.0 3.6e-114 380.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Herpes_UL14 PF03580.9 EGO55364.1 - 0.018 14.8 1.9 0.036 13.8 1.3 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Transaldolase PF00923.14 EGO55367.1 - 1.9e-39 135.5 0.2 2.4e-39 135.1 0.2 1.1 1 0 0 1 1 1 1 Transaldolase UbiA PF01040.13 EGO55368.1 - 3.8e-29 101.6 21.4 3.8e-29 101.6 14.9 1.6 1 1 1 2 2 2 1 UbiA prenyltransferase family Med3 PF11593.3 EGO55368.1 - 4.2 6.5 13.7 5.5 6.1 9.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Myb_DNA-bind_6 PF13921.1 EGO55369.1 - 4.2e-06 26.7 0.6 1.7e-05 24.7 0.1 2.1 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGO55369.1 - 0.007 16.4 0.1 0.018 15.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sugar_tr PF00083.19 EGO55371.1 - 5.9e-118 394.2 23.8 9.7e-118 393.5 16.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO55371.1 - 5.7e-29 100.9 55.6 6e-25 87.6 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lysis_S PF04971.7 EGO55371.1 - 0.0082 15.8 1.0 0.025 14.2 0.1 2.2 2 0 0 2 2 2 1 Lysis protein S p450 PF00067.17 EGO55372.1 - 1.3e-29 103.0 0.0 1.7e-21 76.2 0.3 3.0 1 1 1 2 2 2 2 Cytochrome P450 PYRIN PF02758.11 EGO55372.1 - 0.037 13.7 0.5 0.094 12.4 0.4 1.7 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain Epimerase PF01370.16 EGO55373.1 - 7.1e-13 48.5 0.0 1.5e-12 47.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGO55373.1 - 0.0017 17.2 0.8 0.88 8.4 0.1 2.9 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EGO55373.1 - 0.0022 16.9 0.2 0.043 12.7 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EGO55373.1 - 0.013 14.4 0.0 3 6.6 0.0 2.4 2 0 0 2 2 2 0 RmlD substrate binding domain Amelogenin PF02948.10 EGO55373.1 - 0.093 13.3 0.2 0.68 10.5 0.1 2.1 2 0 0 2 2 2 0 Amelogenin Ank_2 PF12796.2 EGO55375.1 - 2.2e-31 108.0 8.6 1.3e-14 54.2 0.4 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGO55375.1 - 4.8e-21 73.4 9.2 1.6e-07 30.7 0.2 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EGO55375.1 - 2.8e-18 65.5 7.9 6.2e-07 29.4 0.2 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO55375.1 - 8.5e-18 62.6 3.5 1.9e-05 24.4 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EGO55375.1 - 8.9e-18 64.3 10.1 6.1e-08 32.9 0.1 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Imm29 PF15575.1 EGO55375.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.4 1 1 0 1 1 1 0 Immunity protein 29 MFS_1 PF07690.11 EGO55378.1 - 1.3e-19 70.1 46.4 1.2e-17 63.6 32.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO55378.1 - 9.6e-08 30.6 23.3 1.3e-07 30.2 16.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF29 PF01724.11 EGO55379.1 - 0.21 11.4 1.0 1.2 8.9 0.0 2.6 4 0 0 4 4 4 0 Domain of unknown function DUF29 AP2 PF00847.15 EGO55380.1 - 0.039 14.0 0.2 0.079 13.1 0.2 1.5 1 0 0 1 1 1 0 AP2 domain DUF3201 PF11447.3 EGO55380.1 - 0.21 10.9 3.5 0.32 10.3 2.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3201) Polysacc_deac_1 PF01522.16 EGO55381.1 - 6e-12 45.2 0.0 1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF1772 PF08592.6 EGO55381.1 - 3.4e-05 23.5 1.8 3.4e-05 23.5 1.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2194 PF09960.4 EGO55381.1 - 0.13 10.2 0.0 0.18 9.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) SET PF00856.23 EGO55382.1 - 9.8e-13 48.7 0.0 2.5e-11 44.1 0.0 2.4 2 0 0 2 2 2 1 SET domain PUF PF00806.14 EGO55383.1 - 4.5e-17 60.4 0.0 0.078 12.4 0.0 6.6 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat Cob_adeno_trans PF01923.13 EGO55383.1 - 0.0027 17.4 1.6 0.0078 16.0 0.3 2.4 2 1 0 2 2 2 1 Cobalamin adenosyltransferase Trypan_glycop_C PF10659.4 EGO55383.1 - 0.021 15.1 0.9 0.021 15.1 0.6 4.3 5 0 0 5 5 5 0 Trypanosome variant surface glycoprotein C-terminal domain DUF1547 PF07577.6 EGO55385.1 - 0.012 15.2 0.0 0.041 13.5 0.0 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1547) DUF202 PF02656.10 EGO55385.1 - 0.12 12.6 0.2 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) AMMECR1 PF01871.12 EGO55388.1 - 4e-44 149.7 0.0 6.4e-44 149.0 0.0 1.3 1 0 0 1 1 1 1 AMMECR1 Sporozoite_P67 PF05642.6 EGO55388.1 - 0.23 9.2 8.8 0.29 8.9 6.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Atrophin-1 PF03154.10 EGO55388.1 - 0.65 8.0 8.0 0.84 7.6 5.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family Pyridoxal_deC PF00282.14 EGO55389.1 - 5.6e-73 245.5 0.0 5e-61 206.2 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EGO55389.1 - 0.00063 18.5 0.0 0.00095 18.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGO55389.1 - 0.0055 15.8 0.0 0.0076 15.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Ras PF00071.17 EGO55391.1 - 1.2e-38 132.0 0.0 5e-25 87.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EGO55391.1 - 4e-11 43.4 0.0 7.9e-11 42.4 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EGO55391.1 - 0.0047 16.8 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EGO55391.1 - 0.013 14.7 0.0 0.027 13.7 0.0 1.4 2 0 0 2 2 2 0 ADP-ribosylation factor family PRK PF00485.13 EGO55391.1 - 0.056 12.9 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 EGO55391.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.22 EGO55391.1 - 0.14 11.5 0.0 3.1 7.1 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Thi4 PF01946.12 EGO55392.1 - 1.8e-101 338.0 0.2 2.3e-101 337.7 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EGO55392.1 - 1.4e-08 34.0 0.4 3.8e-07 29.3 0.5 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO55392.1 - 2.9e-05 24.0 0.2 8.6e-05 22.4 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGO55392.1 - 8e-05 21.7 0.3 0.00017 20.6 0.2 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EGO55392.1 - 0.00035 20.3 0.1 0.0012 18.6 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EGO55392.1 - 0.00092 19.3 0.0 0.0015 18.6 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO55392.1 - 0.0037 17.1 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO55392.1 - 0.0084 15.2 0.3 0.015 14.4 0.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO55392.1 - 0.012 14.4 1.8 0.028 13.2 0.4 1.9 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 EGO55392.1 - 0.035 13.1 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EGO55392.1 - 0.049 14.0 0.6 0.13 12.6 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 EGO55392.1 - 0.05 11.7 0.0 0.088 10.9 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.9 EGO55392.1 - 0.13 10.6 1.0 0.17 10.3 0.2 1.5 2 0 0 2 2 2 0 HI0933-like protein NIF3 PF01784.13 EGO55394.1 - 3.2e-62 210.2 0.0 4.1e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.13 EGO55395.1 - 1.1e-20 73.3 0.0 1.3e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein VHS PF00790.14 EGO55397.1 - 2.9e-44 150.1 0.0 1.1e-43 148.2 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EGO55397.1 - 2.6e-23 81.8 0.1 6.8e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 EGO55397.1 - 9.6e-21 74.2 0.1 9.6e-21 74.2 0.1 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain AP3B1_C PF14796.1 EGO55397.1 - 0.029 14.0 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal DUF367 PF04034.8 EGO55398.1 - 5.6e-47 158.5 0.1 8e-47 158.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EGO55398.1 - 2.7e-12 46.0 0.7 5.7e-12 45.0 0.5 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Daxx PF03344.10 EGO55398.1 - 0.097 11.1 27.0 0.14 10.6 18.7 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EGO55398.1 - 1.6 7.9 27.6 2.7 7.1 19.1 1.3 1 0 0 1 1 1 0 SDA1 GTP_EFTU PF00009.22 EGO55399.1 - 2.2e-39 134.8 4.0 1.4e-38 132.2 2.8 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EGO55399.1 - 4e-23 81.3 0.1 8.2e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EGO55399.1 - 1.4e-10 41.0 14.1 5.7e-09 35.9 0.0 3.9 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGO55399.1 - 4.8e-08 32.9 0.1 9.3e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO55399.1 - 7.5e-06 25.2 0.4 1.9e-05 23.9 0.3 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 EGO55399.1 - 1.4e-05 24.6 0.2 3e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EGO55399.1 - 2.9e-05 24.5 0.1 5.8e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein IF2_N PF04760.10 EGO55399.1 - 4.3e-05 23.0 0.0 9.6e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Arf PF00025.16 EGO55399.1 - 0.00012 21.3 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGO55399.1 - 0.0024 17.1 0.1 0.0052 16.0 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.1 EGO55399.1 - 0.0053 16.3 5.6 0.16 11.6 2.2 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Dynamin_N PF00350.18 EGO55399.1 - 0.011 15.5 0.5 5.2 6.8 0.1 3.4 2 1 1 3 3 3 0 Dynamin family ArgK PF03308.11 EGO55399.1 - 0.015 14.1 3.2 0.026 13.2 2.0 1.5 1 1 0 1 1 1 0 ArgK protein eIF2A PF08662.6 EGO55401.1 - 2e-78 262.5 0.0 5.7e-78 261.0 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EGO55401.1 - 0.00065 19.4 1.5 1.5 8.7 0.1 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat CDV3 PF15359.1 EGO55401.1 - 0.015 15.3 0.4 0.015 15.3 0.3 2.8 3 1 0 3 3 3 0 Carnitine deficiency-associated protein 3 CP2 PF04516.10 EGO55404.1 - 2.1e-85 285.5 0.0 3.3e-85 284.9 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Phage_G PF02306.10 EGO55404.1 - 0.018 14.7 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 Major spike protein (G protein) Oxysterol_BP PF01237.13 EGO55406.1 - 1.2e-55 188.4 0.0 4.4e-45 153.7 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein GPP34 PF05719.6 EGO55407.1 - 3.8e-63 213.2 0.4 4.7e-63 212.9 0.3 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) SURF6 PF04935.7 EGO55408.1 - 7.6e-51 172.4 46.4 7.6e-51 172.4 32.1 4.2 2 1 1 4 4 4 1 Surfeit locus protein 6 RRP14 PF15459.1 EGO55408.1 - 1.2e-22 79.7 1.5 1.2e-22 79.7 1.1 7.2 6 2 2 8 8 8 1 60S ribosome biogenesis protein Rrp14 XPG_I PF00867.13 EGO55409.1 - 2.8e-24 85.0 0.0 6.9e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EGO55409.1 - 4.9e-23 81.3 0.0 9.2e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EGO55409.1 - 0.0016 17.9 0.0 0.0052 16.3 0.0 1.8 2 0 0 2 2 2 1 XPG domain containing DUF2962 PF11176.3 EGO55410.1 - 1.6e-45 154.4 8.5 1.8e-45 154.2 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) BAR_2 PF10455.4 EGO55410.1 - 1.1 8.0 4.7 1.7 7.4 3.3 1.4 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking MAM33 PF02330.11 EGO55413.1 - 6.4e-31 107.7 0.0 8.2e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein LCCL PF03815.14 EGO55414.1 - 1.5e-17 63.3 0.0 4.4e-17 61.8 0.0 1.7 1 1 0 1 1 1 1 LCCL domain DUF3981 PF13139.1 EGO55414.1 - 2.9 7.9 5.6 0.58 10.1 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3981) Vps51 PF08700.6 EGO55415.1 - 3e-31 107.1 0.2 3e-31 107.1 0.2 1.7 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.7 EGO55415.1 - 0.00017 20.1 1.7 0.00024 19.6 1.2 1.2 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 EGO55415.1 - 0.0062 16.4 0.1 0.014 15.3 0.1 1.7 1 0 0 1 1 1 1 Golgi transport complex subunit 5 ADH_N PF08240.7 EGO55419.1 - 3.2e-08 33.3 0.1 1.8e-07 30.9 0.0 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO55419.1 - 0.042 13.3 0.0 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Dicty_REP PF05086.7 EGO55420.1 - 0.96 7.1 3.0 1.3 6.6 2.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MFS_1 PF07690.11 EGO55423.1 - 7.3e-47 159.7 31.5 7.3e-47 159.7 21.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO55423.1 - 3.2e-09 35.8 8.4 3.2e-09 35.8 5.8 3.0 2 2 0 3 3 3 1 Sugar (and other) transporter CbtA PF09490.5 EGO55423.1 - 0.0067 15.7 0.4 0.0067 15.7 0.3 2.9 3 0 0 3 3 3 1 Probable cobalt transporter subunit (CbtA) OATP PF03137.15 EGO55423.1 - 5.6 4.9 14.6 30 2.4 5.2 3.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1748 PF08520.5 EGO55424.1 - 1.7e-35 120.4 0.1 1.9e-35 120.2 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.16 EGO55425.1 - 3.7e-167 555.2 5.7 4.9e-167 554.8 4.0 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EGO55425.1 - 5e-28 96.9 0.0 1.6e-27 95.3 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EGO55425.1 - 0.00026 19.9 2.3 0.00068 18.5 0.7 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EGO55425.1 - 0.019 13.8 0.2 0.22 10.3 0.0 2.3 2 1 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain APG6 PF04111.7 EGO55427.1 - 2.8 6.9 9.0 0.28 10.1 1.0 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4140 PF13600.1 EGO55427.1 - 2.9 8.4 9.9 6.6 7.2 1.3 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Clr5 PF14420.1 EGO55428.1 - 4.7e-21 74.4 0.3 1.1e-20 73.2 0.2 1.7 1 0 0 1 1 1 1 Clr5 domain ApbA PF02558.11 EGO55429.1 - 4.9e-31 107.2 0.0 6.6e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EGO55429.1 - 4.9e-27 94.4 0.0 8.1e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Shikimate_DH PF01488.15 EGO55429.1 - 0.013 15.6 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MtaB PF12176.3 EGO55429.1 - 0.025 12.9 0.2 0.055 11.8 0.0 1.5 2 0 0 2 2 2 0 Methanol-cobalamin methyltransferase B subunit ThiF PF00899.16 EGO55429.1 - 0.16 11.8 1.7 0.62 9.8 0.6 2.2 2 0 0 2 2 2 0 ThiF family Fungal_trans PF04082.13 EGO55432.1 - 1.8e-19 69.6 0.1 7.3e-19 67.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain PH_10 PF15411.1 EGO55433.1 - 2.4e-39 134.1 0.3 5.2e-39 133.0 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 EGO55433.1 - 3.3e-32 110.3 0.0 7.1e-32 109.3 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 EGO55433.1 - 3.4e-32 111.7 0.1 6.1e-32 110.9 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 EGO55433.1 - 8.1e-08 31.8 0.1 2e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 PB1 domain DUF1903 PF08991.5 EGO55434.1 - 0.037 14.2 0.1 0.059 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) AMP-binding PF00501.23 EGO55436.1 - 4.2e-92 308.7 0.0 5.2e-92 308.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO55436.1 - 8.2e-13 49.1 0.0 2.7e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_8 PF13523.1 EGO55437.1 - 9.1e-41 139.2 0.6 1.3e-40 138.7 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGO55437.1 - 0.0045 17.1 0.1 0.013 15.6 0.1 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Pyr_redox PF00070.22 EGO55438.1 - 3.1e-14 53.1 1.3 1.9e-11 44.1 0.1 3.1 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO55438.1 - 5.6e-10 39.4 0.6 0.002 18.0 0.0 3.3 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO55438.1 - 1.6e-08 34.8 0.0 0.015 15.3 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO55438.1 - 0.00046 19.3 0.2 0.37 9.7 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.7 EGO55438.1 - 0.0039 16.1 0.1 0.0086 15.0 0.1 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein K_oxygenase PF13434.1 EGO55438.1 - 0.0042 16.0 0.0 0.0082 15.0 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EGO55438.1 - 0.029 12.8 1.2 2.3 6.5 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.19 EGO55438.1 - 0.031 13.2 0.3 0.031 13.2 0.2 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EGO55438.1 - 0.14 11.8 0.0 16 5.1 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_8 PF13450.1 EGO55438.1 - 0.46 10.5 3.0 10 6.2 0.0 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain DUF164 PF02591.10 EGO55439.1 - 0.0087 15.8 1.2 5.4 6.9 0.0 2.8 2 0 0 2 2 2 2 Putative zinc ribbon domain DUF2387 PF09526.5 EGO55439.1 - 0.026 14.4 0.3 0.4 10.6 0.0 2.5 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) CBM-like PF14683.1 EGO55439.1 - 0.041 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain III zf-H2C2_2 PF13465.1 EGO55439.1 - 0.047 14.0 8.3 3.6 8.0 0.3 3.9 3 0 0 3 3 3 0 Zinc-finger double domain UPF0547 PF10571.4 EGO55439.1 - 0.07 12.8 3.4 0.14 11.8 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DZR PF12773.2 EGO55439.1 - 0.12 12.2 9.6 0.11 12.2 3.7 2.6 1 1 1 2 2 2 0 Double zinc ribbon zf-CHY PF05495.7 EGO55439.1 - 0.52 10.5 9.6 3.2 7.9 4.9 2.9 2 1 1 3 3 3 0 CHY zinc finger DUF3133 PF11331.3 EGO55439.1 - 0.9 9.1 7.0 18 4.9 1.1 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3133) Translin PF01997.11 EGO55440.1 - 2.7e-63 213.2 0.0 3.2e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Translin family MRI PF15325.1 EGO55440.1 - 0.81 10.6 5.0 7.9 7.5 0.9 2.4 2 0 0 2 2 2 0 Modulator of retrovirus infection Amidohydro_2 PF04909.9 EGO55441.1 - 1.6e-48 165.6 1.1 2e-48 165.3 0.7 1.1 1 0 0 1 1 1 1 Amidohydrolase Mannosyl_trans PF05007.8 EGO55442.1 - 2.9e-82 276.2 9.5 4e-82 275.7 6.6 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EGO55442.1 - 4.8e-17 61.9 0.0 4.8e-17 61.9 0.0 2.1 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U F-box-like PF12937.2 EGO55443.1 - 0.00017 21.2 1.0 0.00086 18.9 0.6 2.2 2 0 0 2 2 2 1 F-box-like Peptidase_S8 PF00082.17 EGO55445.1 - 9.9e-46 156.1 15.8 9.9e-46 156.1 11.0 1.5 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 EGO55445.1 - 0.0002 21.8 0.1 0.00047 20.6 0.1 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 SQS_PSY PF00494.14 EGO55446.1 - 1.1e-39 136.3 0.0 3.2e-39 134.8 0.0 1.7 2 0 0 2 2 2 1 Squalene/phytoene synthase tRNA_lig_CPD PF08302.6 EGO55446.1 - 0.083 12.0 0.6 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain RmlD_sub_bind PF04321.12 EGO55447.1 - 3.9e-14 52.2 0.0 6.5e-14 51.4 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EGO55447.1 - 2.3e-13 50.1 0.0 4.1e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGO55447.1 - 0.00021 20.2 0.0 0.00062 18.7 0.0 1.7 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EGO55447.1 - 0.00049 20.0 0.1 0.0012 18.8 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EGO55447.1 - 0.034 12.8 0.0 0.071 11.7 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DnaJ-X PF14308.1 EGO55448.1 - 1.5e-71 239.8 3.6 1.5e-71 239.8 2.5 1.8 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EGO55448.1 - 2.8e-27 94.2 1.2 6.3e-27 93.1 0.8 1.7 1 0 0 1 1 1 1 DnaJ domain Cyt-b5 PF00173.23 EGO55449.1 - 8.6e-16 57.5 0.0 1.3e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BRCT PF00533.21 EGO55452.1 - 0.031 14.4 0.3 0.39 10.9 0.1 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Arr-ms PF12120.3 EGO55452.1 - 0.088 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Rifampin ADP-ribosyl transferase Ribosomal_S30 PF04758.9 EGO55453.1 - 2.9e-29 100.5 4.9 3.2e-29 100.4 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_S5 PF00333.15 EGO55454.1 - 2.2e-28 97.7 2.1 2.2e-28 97.7 1.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EGO55454.1 - 7.2e-21 73.2 0.0 1.4e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain WSC PF01822.14 EGO55456.1 - 0.0011 18.7 0.8 0.0017 18.2 0.5 1.3 1 0 0 1 1 1 1 WSC domain Grp1_Fun34_YaaH PF01184.14 EGO55459.1 - 2.9e-88 294.6 15.8 3.8e-88 294.2 11.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family FAD_binding_2 PF00890.19 EGO55460.1 - 1.1e-53 182.6 4.3 1.5e-53 182.1 3.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGO55460.1 - 8.2e-08 31.5 0.3 1.4e-07 30.7 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO55460.1 - 2.8e-07 30.4 0.9 2.2e-06 27.6 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EGO55460.1 - 5.3e-06 25.7 2.6 8.4e-06 25.1 1.6 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO55460.1 - 0.00084 19.4 0.1 0.0024 17.9 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO55460.1 - 0.0079 15.3 0.4 0.02 13.9 0.2 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EGO55460.1 - 0.011 15.5 0.0 0.091 12.6 0.0 2.3 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO55460.1 - 0.013 14.0 0.6 0.013 14.0 0.4 2.4 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.17 EGO55460.1 - 0.02 13.7 7.6 0.02 13.7 1.9 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EGO55460.1 - 0.076 11.9 0.1 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Sulfatase PF00884.18 EGO55461.1 - 5.5e-73 245.8 0.2 7e-73 245.4 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EGO55461.1 - 0.00027 20.3 3.7 0.0098 15.2 2.6 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.11 EGO55462.1 - 3.6e-24 85.1 34.6 3.6e-24 85.1 24.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO55462.1 - 1.5e-09 36.9 25.4 2.3e-09 36.3 6.3 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter WD40 PF00400.27 EGO55463.1 - 1.4e-20 72.3 13.1 1.7e-08 33.9 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Ribosomal_L36 PF00444.13 EGO55464.1 - 3.5e-21 74.8 9.6 3.5e-21 74.8 6.6 1.7 2 0 0 2 2 2 1 Ribosomal protein L36 Glycos_trans_3N PF02885.12 EGO55465.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain E1_dh PF00676.15 EGO55465.1 - 0.08 11.6 0.1 2.6 6.6 0.0 2.0 2 0 0 2 2 2 0 Dehydrogenase E1 component DUF2156 PF09924.4 EGO55465.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) EF1_GNE PF00736.14 EGO55467.1 - 7.6e-32 108.8 1.4 1.3e-31 108.1 1.0 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EGO55467.1 - 8.9e-15 54.5 8.5 8.9e-15 54.5 5.9 2.4 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.20 EGO55467.1 - 0.0028 17.6 0.7 0.0064 16.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO55467.1 - 0.0047 17.3 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MARVEL PF01284.18 EGO55468.1 - 8.3e-13 48.3 20.5 1e-12 48.0 14.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain CTP_transf_1 PF01148.15 EGO55468.1 - 0.014 15.0 9.3 0.018 14.7 6.5 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family Fig1 PF12351.3 EGO55468.1 - 0.074 12.9 16.5 1.1 9.1 11.4 2.0 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 FA_desaturase PF00487.19 EGO55468.1 - 7.6 5.8 10.3 9.6 5.5 7.2 1.2 1 0 0 1 1 1 0 Fatty acid desaturase PIG-S PF10510.4 EGO55469.1 - 3.9e-148 494.3 0.2 4.6e-148 494.1 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Kelch_3 PF13415.1 EGO55470.1 - 1e-13 50.9 0.6 1.2e-09 38.0 0.0 5.0 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_4 PF13418.1 EGO55470.1 - 3.5e-09 36.2 0.2 0.0099 15.6 0.0 5.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EGO55470.1 - 6.4e-08 32.3 0.2 0.0051 16.7 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 EGO55470.1 - 1.3e-05 25.1 0.2 1.8 8.8 0.0 4.5 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 EGO55470.1 - 0.00013 21.5 0.0 0.0018 17.9 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 EGO55470.1 - 0.0012 18.3 0.0 1.5 8.4 0.0 3.7 3 0 0 3 3 3 1 Kelch motif BTB PF00651.26 EGO55470.1 - 0.0031 17.4 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain CTP_transf_2 PF01467.21 EGO55471.1 - 0.017 15.1 0.9 0.56 10.2 0.1 2.7 2 1 0 2 2 2 0 Cytidylyltransferase Fungal_trans PF04082.13 EGO55472.1 - 4.1e-23 81.5 0.0 6.2e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO55472.1 - 1.9e-06 27.6 10.3 3.1e-06 26.9 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 EGO55473.1 - 1.1e-41 142.9 0.0 1.7e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 EGO55473.1 - 1.4e-22 79.5 0.1 3.3e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 EGO55473.1 - 4.8e-21 75.2 0.0 7.6e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 EGO55473.1 - 5.4e-12 45.9 0.1 1.2e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_29 PF13555.1 EGO55473.1 - 0.0083 15.6 0.0 0.83 9.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGO55473.1 - 0.022 15.5 0.0 0.045 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGO55473.1 - 0.023 13.8 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EGO55473.1 - 0.1 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGO55473.1 - 0.2 11.5 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.19 EGO55474.1 - 2.6e-138 461.3 26.8 2.9e-138 461.2 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO55474.1 - 2e-22 79.4 38.6 2e-22 79.4 26.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Shikimate_dh_N PF08501.6 EGO55475.1 - 9.9e-20 70.3 0.0 1.7e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EGO55475.1 - 2.4e-19 69.7 0.0 3.8e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 EGO55475.1 - 0.013 14.3 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family VESA1_N PF12785.2 EGO55475.1 - 0.098 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 AP_endonuc_2 PF01261.19 EGO55476.1 - 7.1e-34 116.9 0.0 8.8e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DHquinase_II PF01220.14 EGO55477.1 - 3.6e-56 188.3 0.0 2.6e-31 107.8 0.0 2.0 2 0 0 2 2 2 2 Dehydroquinase class II Inositol_P PF00459.20 EGO55478.1 - 1.1e-84 283.9 0.0 1.2e-84 283.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family WD40 PF00400.27 EGO55479.1 - 6.4e-06 25.8 4.9 0.52 10.2 0.8 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat CDC45 PF02724.9 EGO55479.1 - 1.9 6.4 11.7 0.018 13.0 2.3 1.7 2 0 0 2 2 2 0 CDC45-like protein Glyco_hydro_18 PF00704.23 EGO55480.1 - 1.3e-46 159.6 0.0 1.8e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Abhydrolase_6 PF12697.2 EGO55481.1 - 8.4e-20 71.6 3.7 1.1e-19 71.2 2.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO55481.1 - 3.8e-08 33.2 0.6 1.4e-07 31.4 0.5 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO55481.1 - 0.014 14.9 0.0 0.052 13.0 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Nop14 PF04147.7 EGO55482.1 - 0.43 8.4 13.3 0.51 8.1 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EGO55482.1 - 0.87 7.5 18.9 0.031 12.3 4.9 2.0 2 0 0 2 2 2 0 CDC45-like protein Daxx PF03344.10 EGO55482.1 - 2 6.8 15.5 0.083 11.3 3.1 2.0 2 0 0 2 2 2 0 Daxx Family DHH PF01368.15 EGO55484.1 - 0.099 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 DHH family Rhodanese PF00581.15 EGO55485.1 - 1e-19 70.9 0.0 1.6e-11 44.5 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain zf-Apc11 PF12861.2 EGO55486.1 - 3e-45 152.0 11.5 3.2e-45 151.8 8.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EGO55486.1 - 1.6e-33 114.6 10.8 1.8e-33 114.4 7.5 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGO55486.1 - 5.4e-09 35.7 16.5 3.2e-08 33.2 11.5 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGO55486.1 - 6.9e-05 22.4 12.9 7.2e-05 22.3 5.5 2.3 1 1 2 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO55486.1 - 8.7e-05 22.0 14.7 0.0004 19.9 10.2 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGO55486.1 - 0.00024 20.6 10.5 0.001 18.6 1.8 2.3 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EGO55486.1 - 0.00026 20.7 4.2 0.00026 20.7 2.9 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EGO55486.1 - 0.00048 20.0 15.2 0.0055 16.7 10.5 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EGO55486.1 - 0.004 17.0 17.4 0.12 12.3 12.1 3.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_5 PF14634.1 EGO55486.1 - 0.018 14.7 17.0 0.46 10.2 12.2 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-HIT PF04438.11 EGO55486.1 - 0.038 13.6 1.6 0.038 13.6 1.1 2.4 3 0 0 3 3 2 0 HIT zinc finger zf-Nse PF11789.3 EGO55486.1 - 0.038 13.5 6.5 0.065 12.7 4.5 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Opy2 PF09463.5 EGO55486.1 - 0.096 12.7 11.3 0.63 10.1 4.5 2.3 2 0 0 2 2 2 0 Opy2 protein DUF2256 PF10013.4 EGO55486.1 - 0.27 11.0 0.5 0.27 11.0 0.3 3.8 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-DBF PF07535.7 EGO55486.1 - 0.78 9.4 3.8 2.3 7.9 0.1 2.3 2 0 0 2 2 2 0 DBF zinc finger zf-RING-like PF08746.6 EGO55486.1 - 1.2 9.1 14.3 5.9 6.9 9.9 2.1 1 1 0 1 1 1 0 RING-like domain zinc-ribbons_6 PF07191.7 EGO55486.1 - 1.7 8.4 9.9 2.3 8.0 0.1 2.6 1 1 2 3 3 3 0 zinc-ribbons RINGv PF12906.2 EGO55486.1 - 3.1 7.8 13.3 7.9 6.6 8.8 2.1 1 1 0 1 1 1 0 RING-variant domain DZR PF12773.2 EGO55486.1 - 4.4 7.1 13.5 8.8 6.2 4.5 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-HC5HC2H_2 PF13832.1 EGO55486.1 - 4.8 7.2 11.5 2.2 8.3 4.6 2.2 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 EGO55486.1 - 5.3 6.8 9.8 0.28 10.9 2.7 2.0 2 1 0 2 2 1 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 EGO55486.1 - 5.5 7.2 12.8 2.7 8.1 5.2 2.4 1 1 1 2 2 2 0 PHD-like zinc-binding domain DUF329 PF03884.9 EGO55486.1 - 9.2 5.9 10.0 1.3 8.6 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF329) RecR PF02132.10 EGO55486.1 - 9.5 5.7 6.6 4.9 6.6 0.2 2.9 3 0 0 3 3 3 0 RecR protein Elf1 PF05129.8 EGO55486.1 - 9.5 6.0 7.9 1.1e+02 2.5 5.5 2.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like SNARE PF05739.14 EGO55488.1 - 2e-11 43.4 14.7 1e-10 41.1 6.1 3.0 2 1 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EGO55488.1 - 2.1e-09 37.4 1.5 2.1e-09 37.4 1.1 2.6 1 1 0 2 2 2 1 Syntaxin Spectrin PF00435.16 EGO55488.1 - 0.0013 18.9 10.7 0.093 13.0 0.0 3.3 2 1 1 3 3 3 3 Spectrin repeat YukC PF10140.4 EGO55488.1 - 0.012 14.2 1.1 0.022 13.3 0.7 1.5 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF912 PF06024.7 EGO55488.1 - 0.019 15.0 0.3 0.064 13.3 0.2 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 EGO55488.1 - 0.088 12.4 14.4 0.019 14.6 5.1 2.1 1 1 1 2 2 2 0 Rifin/stevor family DUF2721 PF11026.3 EGO55488.1 - 0.15 11.7 3.9 4.8 6.8 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) PBP1_TM PF14812.1 EGO55488.1 - 0.35 11.1 0.0 0.35 11.1 0.0 2.3 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DASH_Dad1 PF08649.5 EGO55488.1 - 0.63 9.7 6.3 1.3 8.7 0.1 3.3 2 2 1 3 3 3 0 DASH complex subunit Dad1 DUF2077 PF09850.4 EGO55488.1 - 0.66 9.3 4.7 2.2 7.6 0.1 2.8 2 2 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF4094 PF13334.1 EGO55488.1 - 0.77 10.1 4.5 0.86 10.0 0.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) PspA_IM30 PF04012.7 EGO55488.1 - 2.1 7.6 19.6 0.49 9.7 11.0 1.8 2 0 0 2 2 2 0 PspA/IM30 family Synaptobrevin PF00957.16 EGO55488.1 - 2.6 7.7 11.3 15 5.3 7.8 2.4 1 1 0 1 1 1 0 Synaptobrevin Fib_alpha PF08702.5 EGO55488.1 - 3 7.9 13.4 7.1 6.7 0.4 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 EGO55488.1 - 6.4 6.3 15.6 0.99 9.0 5.4 2.3 1 1 1 2 2 2 0 Mnd1 family Memo PF01875.12 EGO55489.1 - 2.4e-71 239.8 0.0 2.9e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein MMS19_C PF12460.3 EGO55490.1 - 0.049 12.3 0.1 0.058 12.1 0.0 1.1 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal IMS PF00817.15 EGO55491.1 - 6.5e-42 142.8 0.1 1.2e-41 141.9 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGO55491.1 - 2.1e-16 59.9 0.3 4.4e-16 58.9 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EGO55491.1 - 2.1e-06 27.4 0.0 5.2e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif TrkH PF02386.11 EGO55492.1 - 8e-85 284.5 14.4 2.3e-82 276.4 4.1 2.1 2 0 0 2 2 2 2 Cation transport protein Rossmann-like PF10727.4 EGO55492.1 - 0.042 13.5 0.3 0.53 10.0 0.1 2.4 2 0 0 2 2 2 0 Rossmann-like domain HemN_C PF06969.11 EGO55494.1 - 0.032 14.2 0.0 0.065 13.3 0.0 1.6 1 1 0 1 1 1 0 HemN C-terminal domain FKBP_C PF00254.23 EGO55495.1 - 2.6e-32 110.6 0.0 4.4e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ApoLp-III PF07464.6 EGO55495.1 - 0.016 15.2 7.1 0.021 14.8 4.9 1.1 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) MT0933_antitox PF14013.1 EGO55495.1 - 0.13 12.4 10.9 0.58 10.2 7.6 2.1 1 1 0 1 1 1 0 MT0933-like antitoxin protein EspB PF05802.6 EGO55495.1 - 0.17 10.8 8.4 0.22 10.4 5.8 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein DUF883 PF05957.8 EGO55495.1 - 0.38 11.1 9.1 0.98 9.8 6.3 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) LEA_4 PF02987.11 EGO55495.1 - 0.72 9.7 19.5 0.17 11.7 8.1 2.3 1 1 1 2 2 2 0 Late embryogenesis abundant protein Remorin_C PF03763.8 EGO55495.1 - 0.97 8.9 9.2 1.6 8.3 6.4 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region DUF719 PF05334.8 EGO55495.1 - 3.1 7.8 7.7 6.8 6.6 4.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF719) Tape_meas_lam_C PF09718.5 EGO55495.1 - 3.3 7.6 6.5 4.9 7.1 0.6 2.2 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ATP-synt_B PF00430.13 EGO55495.1 - 3.5 7.4 9.4 5.3 6.8 6.5 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) PPI_Ypi1 PF07491.6 EGO55497.1 - 0.054 13.1 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor RPEL PF02755.10 EGO55498.1 - 3.1e-15 54.9 10.6 3.6e-08 32.4 0.9 3.1 3 0 0 3 3 3 2 RPEL repeat TLD PF07534.11 EGO55499.1 - 5.3e-28 97.7 0.0 1.8e-27 96.0 0.0 1.8 1 1 0 1 1 1 1 TLD MUG2_C PF08593.5 EGO55499.1 - 3.9e-15 55.8 0.1 8.8e-15 54.6 0.1 1.7 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal HIG_1_N PF04588.8 EGO55500.1 - 7.9e-24 83.1 1.2 1.3e-23 82.4 0.8 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Fibrinogen_BP PF08017.6 EGO55500.1 - 0.0044 15.2 1.2 0.0057 14.9 0.8 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein DUF4093 PF13331.1 EGO55500.1 - 0.02 15.0 1.0 0.036 14.2 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4093) UcrQ PF02939.11 EGO55500.1 - 0.024 14.4 0.6 0.098 12.4 0.3 2.0 1 1 0 2 2 2 0 UcrQ family Peptidase_S49_N PF08496.5 EGO55500.1 - 0.26 11.0 2.6 0.36 10.6 1.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SHR3_chaperone PF08229.6 EGO55500.1 - 1.5 7.7 5.5 2.4 7.0 3.8 1.5 1 1 0 1 1 1 0 ER membrane protein SH3 PALP PF00291.20 EGO55501.1 - 9.9e-75 251.5 0.9 1.2e-74 251.3 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EGO55501.1 - 7.8e-33 111.9 0.0 8.2e-18 63.7 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Abhydrolase_2 PF02230.11 EGO55503.1 - 0.056 12.8 0.0 0.071 12.5 0.0 1.4 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Ctr PF04145.10 EGO55503.1 - 0.24 11.4 1.3 0.33 10.9 0.9 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Band_3_cyto PF07565.8 EGO55503.1 - 0.37 10.2 1.8 0.44 10.0 1.2 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4614 PF15391.1 EGO55503.1 - 1.1 8.9 11.2 1.4 8.6 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) RVT_1 PF00078.22 EGO55515.1 - 6.2e-05 22.4 0.5 6.4e-05 22.4 0.3 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2-oxoacid_dh PF00198.18 EGO55516.1 - 3.1e-81 272.0 0.1 4.1e-81 271.6 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGO55516.1 - 3.2e-20 71.5 2.4 6.4e-20 70.5 1.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 EGO55516.1 - 8.3e-06 25.1 0.5 0.00094 18.4 0.0 2.6 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EGO55516.1 - 7.2e-05 22.3 0.9 0.012 15.2 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 EGO55516.1 - 0.006 16.9 0.5 0.04 14.2 0.2 2.1 1 1 0 1 1 1 1 HlyD family secretion protein RnfC_N PF13375.1 EGO55516.1 - 0.02 14.6 0.3 0.47 10.1 0.0 2.5 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 EGO55516.1 - 0.028 14.0 0.3 0.054 13.1 0.2 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Neisseria_TspB PF05616.8 EGO55516.1 - 0.6 8.4 6.7 0.78 8.0 4.6 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF1180 PF06679.7 EGO55516.1 - 1.7 8.5 5.6 2.8 7.7 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HpaP PF09483.5 EGO55516.1 - 8.8 6.2 13.3 16 5.3 9.2 1.4 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Histone PF00125.19 EGO55517.1 - 8.4e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGO55517.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGO55519.1 - 9.3e-22 76.9 0.2 1.3e-21 76.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGO55519.1 - 3.8e-05 23.6 0.0 9.9e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EGO55519.1 - 0.00021 21.5 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EGO55519.1 - 0.011 15.2 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 EGO55519.1 - 0.03 14.8 0.5 0.041 14.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) R3H PF01424.17 EGO55520.1 - 2.5e-13 49.5 0.0 6e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EGO55520.1 - 5.5e-13 48.4 4.7 1.2e-12 47.3 3.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EGO55520.1 - 0.0084 15.9 2.2 0.0084 15.9 1.5 2.5 3 0 0 3 3 3 1 DExH-box splicing factor binding site Peptidase_C54 PF03416.14 EGO55521.1 - 1.2e-97 326.3 0.0 1.5e-97 326.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 DnaJ PF00226.26 EGO55522.1 - 4.8e-25 87.0 4.9 7.3e-25 86.4 0.5 2.5 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 EGO55522.1 - 1.5e-10 40.8 1.4 1.5e-10 40.8 1.0 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGO55522.1 - 5e-10 39.3 4.5 1.5e-05 25.0 0.4 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EGO55522.1 - 3.6e-09 36.4 2.4 3.6e-09 36.4 1.6 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EGO55522.1 - 4.3e-06 26.4 9.7 0.0036 17.1 1.6 2.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO55522.1 - 3.5e-05 23.8 8.6 0.013 15.8 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO55522.1 - 0.0036 17.5 6.8 0.034 14.4 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger Lact-deh-memb PF09330.6 EGO55522.1 - 0.063 12.6 0.3 0.095 12.0 0.2 1.2 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding RPT PF13446.1 EGO55522.1 - 0.092 12.1 0.1 0.43 10.0 0.0 2.1 2 0 0 2 2 2 0 A repeated domain in UCH-protein zf-H2C2_2 PF13465.1 EGO55522.1 - 0.13 12.5 1.3 3.9 7.9 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain DUF2387 PF09526.5 EGO55522.1 - 0.18 11.7 5.7 0.08 12.8 1.7 2.1 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) AKAP95 PF04988.7 EGO55522.1 - 0.79 9.4 8.7 0.037 13.8 1.2 2.1 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) SPX PF03105.14 EGO55523.1 - 1.2e-40 140.0 0.0 1.6e-40 139.6 0.0 1.2 1 0 0 1 1 1 1 SPX domain zf-RING_2 PF13639.1 EGO55523.1 - 3.4e-05 23.5 13.7 6.6e-05 22.6 9.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EGO55523.1 - 6.8e-05 22.6 13.2 0.00013 21.8 9.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EGO55523.1 - 0.00014 21.4 10.9 0.00025 20.6 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO55523.1 - 0.00026 20.5 13.7 0.00054 19.5 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO55523.1 - 0.0025 17.8 14.8 0.0052 16.7 10.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO55523.1 - 0.003 17.2 10.1 0.0063 16.2 7.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGO55523.1 - 0.0093 15.5 4.6 0.0093 15.5 3.2 1.8 2 0 0 2 2 1 1 RING/Ubox like zinc-binding domain DZR PF12773.2 EGO55523.1 - 1.1 9.1 6.0 2.2 8.1 4.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_UBOX PF13445.1 EGO55523.1 - 1.6 8.5 6.5 5 6.9 4.5 1.9 1 1 0 1 1 1 0 RING-type zinc-finger FYVE_2 PF02318.11 EGO55523.1 - 2.8 7.8 11.8 2.2 8.1 6.6 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger Cys_Met_Meta_PP PF01053.15 EGO55524.1 - 7.7e-40 136.3 0.0 1.1e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EGO55524.1 - 0.0022 16.9 0.0 0.0057 15.6 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II CMD PF02627.15 EGO55524.1 - 0.041 13.7 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Glyoxalase PF00903.20 EGO55525.1 - 0.015 15.2 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EMG1 PF03587.9 EGO55526.1 - 6.7e-79 263.8 0.0 7.7e-79 263.6 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase PH PF00169.24 EGO55528.1 - 1.9e-06 27.9 0.0 4.7e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 EGO55528.1 - 0.018 12.6 0.1 0.026 12.1 0.1 1.1 1 0 0 1 1 1 0 Prominin DnaJ PF00226.26 EGO55529.1 - 1.7e-24 85.3 2.3 1.7e-24 85.3 1.6 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 EGO55529.1 - 1.1e-18 66.6 11.2 1.8e-08 33.9 0.0 5.4 2 1 4 6 6 6 6 TPR repeat TPR_1 PF00515.23 EGO55529.1 - 7.9e-17 60.0 6.4 0.00086 18.8 0.0 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EGO55529.1 - 1.8e-15 55.4 15.0 0.04 13.8 0.0 8.6 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGO55529.1 - 2.9e-15 54.8 0.5 0.038 13.7 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGO55529.1 - 7.5e-14 50.9 10.4 0.016 15.8 0.2 7.1 2 1 5 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGO55529.1 - 1.8e-12 47.6 12.8 0.00015 22.3 0.1 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGO55529.1 - 1.6e-11 43.8 9.8 0.043 14.2 0.9 7.0 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_9 PF13371.1 EGO55529.1 - 8.2e-10 38.4 0.6 0.012 15.4 0.0 4.4 3 2 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGO55529.1 - 4e-07 30.2 14.9 0.01 16.1 0.5 5.6 3 1 5 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGO55529.1 - 9.7e-07 28.1 6.0 0.9 9.4 0.2 5.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO55529.1 - 6.9e-06 25.9 13.9 0.003 17.4 0.1 5.0 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGO55529.1 - 3e-05 23.8 6.9 0.0069 16.5 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EGO55529.1 - 0.00015 21.8 11.9 0.091 12.9 0.1 4.6 4 1 1 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 EGO55529.1 - 0.0063 16.8 5.5 1.1 9.5 0.0 4.2 2 1 2 4 4 4 1 Bacterial transcriptional activator domain TPR_15 PF13429.1 EGO55529.1 - 0.033 13.2 7.8 4.3 6.3 0.2 4.2 4 2 1 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.2 EGO55529.1 - 0.54 10.0 7.3 4.9 6.9 0.3 3.9 4 0 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_20 PF14561.1 EGO55529.1 - 0.57 10.3 9.5 9.3 6.4 0.0 4.5 2 2 3 5 5 5 0 Tetratricopeptide repeat Enkurin PF13864.1 EGO55529.1 - 9.4 6.5 10.3 0.81 9.9 0.4 3.1 3 1 0 3 3 3 0 Calmodulin-binding Mito_carr PF00153.22 EGO55530.1 - 2e-73 242.1 6.5 3.6e-25 87.5 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein APG9 PF04109.11 EGO55531.1 - 7.6e-164 544.9 3.1 1e-163 544.5 2.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 FAM216B PF15107.1 EGO55531.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 FAM216B protein family COG6 PF06419.6 EGO55532.1 - 5.3e-232 771.3 6.3 6.1e-232 771.1 4.4 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.6 EGO55532.1 - 0.0027 17.5 0.1 0.018 14.9 0.1 2.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DASH_Dad3 PF08656.5 EGO55532.1 - 0.0035 17.0 1.4 0.041 13.5 0.0 3.0 3 0 0 3 3 3 1 DASH complex subunit Dad3 RmuC PF02646.11 EGO55532.1 - 0.0036 16.1 1.6 0.0083 14.9 1.1 1.6 1 0 0 1 1 1 1 RmuC family AAA PF00004.24 EGO55533.1 - 2.3e-16 60.2 1.7 1.4e-10 41.4 0.1 2.7 2 1 1 3 3 2 2 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EGO55533.1 - 3.6e-09 36.3 0.7 4.4e-06 26.4 0.0 3.6 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EGO55533.1 - 0.00011 22.3 0.0 0.00049 20.2 0.0 2.2 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EGO55533.1 - 0.00056 19.0 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EGO55533.1 - 0.0013 18.3 1.2 0.0042 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGO55533.1 - 0.0016 18.2 0.2 0.0062 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EGO55533.1 - 0.0021 17.7 0.1 0.007 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.16 EGO55533.1 - 0.0022 17.4 0.0 0.0047 16.3 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase IstB_IS21 PF01695.12 EGO55533.1 - 0.0024 17.3 0.0 0.0049 16.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EGO55533.1 - 0.0027 18.5 0.0 0.058 14.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EGO55533.1 - 0.0029 17.3 0.0 0.0097 15.6 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EGO55533.1 - 0.0033 16.6 0.5 0.0078 15.3 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EGO55533.1 - 0.0036 17.3 5.7 0.016 15.1 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_28 PF13521.1 EGO55533.1 - 0.0063 16.4 0.7 0.073 13.0 0.1 2.8 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 EGO55533.1 - 0.0077 14.9 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EGO55533.1 - 0.01 15.2 0.0 0.059 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EGO55533.1 - 0.021 13.7 0.0 0.039 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EGO55533.1 - 0.024 14.2 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF927 PF06048.6 EGO55533.1 - 0.034 13.4 0.0 0.068 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF927) Arch_ATPase PF01637.13 EGO55533.1 - 0.045 13.4 0.0 0.59 9.7 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase TPR_2 PF07719.12 EGO55533.1 - 0.057 13.3 0.1 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat NACHT PF05729.7 EGO55533.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EGO55533.1 - 0.11 12.6 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.11 EGO55533.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Ribosomal_S17 PF00366.15 EGO55534.1 - 1e-07 31.8 0.4 1.7e-07 31.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 GAS2 PF02187.12 EGO55534.1 - 0.073 12.8 0.1 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain GTP_EFTU_D2 PF03144.20 EGO55534.1 - 0.1 12.7 0.2 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu domain 2 DUF2013 PF09431.5 EGO55535.1 - 3.3e-27 94.9 2.9 3.3e-27 94.9 2.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Acetyltransf_1 PF00583.19 EGO55536.1 - 7.4e-19 67.5 0.0 1.2e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGO55536.1 - 2.3e-10 40.0 0.0 6.1e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 EGO55536.1 - 3.8e-10 39.7 0.0 5.6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO55536.1 - 2.2e-09 37.4 0.0 3.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGO55536.1 - 4e-09 36.7 0.0 5.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO55536.1 - 2e-07 31.0 0.0 2.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGO55536.1 - 1.5e-06 28.0 0.0 3.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGO55536.1 - 0.0013 18.7 0.0 0.0028 17.5 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGO55536.1 - 0.0029 17.4 0.0 0.0067 16.2 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.1 EGO55536.1 - 0.14 11.9 0.1 0.97 9.2 0.0 2.3 2 1 0 2 2 2 0 ESCO1/2 acetyl-transferase LCAT PF02450.10 EGO55537.1 - 8.3e-95 318.0 0.0 1e-94 317.7 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.5 EGO55537.1 - 0.072 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Metallopep PF12044.3 EGO55538.1 - 3e-172 572.8 0.0 3.8e-172 572.5 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 EGO55538.1 - 9.4e-07 28.7 0.1 1.6e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Jacalin-like lectin domain W2 PF02020.13 EGO55539.1 - 1.9e-16 59.7 2.2 7.7e-16 57.8 1.5 2.1 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EGO55539.1 - 2.3e-07 29.9 4.4 0.023 14.1 0.1 3.9 1 1 3 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EGO55539.1 - 0.00026 20.3 0.0 0.00048 19.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexokinase_2 PF03727.11 EGO55539.1 - 0.035 13.3 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Hexokinase Hexapep_2 PF14602.1 EGO55539.1 - 0.04 13.4 0.3 9 5.9 0.3 3.4 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 EGO55539.1 - 0.074 13.1 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 MobA-like NTP transferase domain HSF_DNA-bind PF00447.12 EGO55541.1 - 1e-37 128.4 0.2 2e-37 127.4 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 EGO55541.1 - 4.9e-21 74.8 0.6 9.1e-21 73.9 0.4 1.5 1 0 0 1 1 1 1 Response regulator receiver domain CENP-H PF05837.7 EGO55541.1 - 0.025 14.7 5.2 0.057 13.5 3.6 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) CENP-Q PF13094.1 EGO55541.1 - 0.026 14.5 1.7 0.059 13.3 1.2 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF972 PF06156.8 EGO55541.1 - 0.091 13.1 1.2 0.23 11.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3143 PF11341.3 EGO55543.1 - 0.086 12.7 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) Whi5 PF08528.6 EGO55544.1 - 4.2e-10 38.9 0.2 8.8e-10 37.9 0.1 1.6 1 0 0 1 1 1 1 Whi5 like Vac14_Fig4_bd PF11916.3 EGO55547.1 - 3.4e-83 277.2 8.3 3.4e-83 277.2 5.8 1.6 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EGO55547.1 - 1.8e-46 156.4 0.0 3.1e-42 142.8 0.0 4.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EGO55547.1 - 4.6e-09 35.6 4.1 0.00013 21.7 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 EGO55547.1 - 1.7e-08 34.6 5.7 0.0015 18.9 0.0 5.8 5 1 1 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.1 EGO55547.1 - 7.6e-06 26.1 5.6 0.037 14.2 0.0 5.2 5 0 0 5 5 5 2 HEAT repeats Arm PF00514.18 EGO55547.1 - 0.00037 20.2 0.1 0.8 9.6 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat FA_desaturase PF00487.19 EGO55549.1 - 9.1e-35 120.3 31.2 1.4e-34 119.7 21.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EGO55549.1 - 2.3e-12 46.5 0.0 4.4e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAM60A PF15396.1 EGO55549.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Pyr_redox_dim PF02852.17 EGO55550.1 - 1.6e-40 137.5 0.1 5.4e-40 135.8 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EGO55550.1 - 2.2e-36 125.6 16.3 2.4e-35 122.2 10.8 4.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO55550.1 - 4.9e-24 84.5 11.2 2.2e-21 76.0 0.8 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO55550.1 - 1.1e-11 44.5 3.5 1.1e-05 25.3 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EGO55550.1 - 1.6e-10 40.6 6.7 1e-09 38.0 0.2 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO55550.1 - 1.9e-09 36.8 7.5 2.3e-07 30.0 2.3 3.2 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.17 EGO55550.1 - 1.3e-08 34.1 12.5 9.5e-07 27.9 2.9 3.3 2 2 1 3 3 3 2 Glucose inhibited division protein A DAO PF01266.19 EGO55550.1 - 4.7e-08 32.3 17.1 0.00026 20.0 1.8 4.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO55550.1 - 1.4e-07 31.8 3.3 6.9e-05 22.9 0.7 2.7 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO55550.1 - 3.6e-07 29.5 2.8 1.7e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EGO55550.1 - 1.8e-06 26.7 13.2 0.00012 20.7 1.6 4.0 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.16 EGO55550.1 - 3.2e-06 26.8 1.3 0.0035 16.9 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 EGO55550.1 - 0.00016 20.7 0.1 0.66 8.8 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EGO55550.1 - 0.00019 20.6 9.3 0.24 10.4 0.2 3.2 3 0 0 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.1 EGO55550.1 - 0.001 19.3 1.2 0.37 11.0 0.1 3.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EGO55550.1 - 0.011 14.6 5.2 0.037 12.9 0.6 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein THF_DHG_CYH_C PF02882.14 EGO55550.1 - 0.08 12.0 1.0 22 4.0 0.0 3.7 4 1 0 4 4 4 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Trp_halogenase PF04820.9 EGO55550.1 - 0.11 11.0 5.7 0.22 10.1 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase FMO-like PF00743.14 EGO55550.1 - 0.22 9.6 1.4 0.65 8.1 0.5 2.0 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like 3HCDH_N PF02737.13 EGO55550.1 - 0.28 10.8 6.9 0.11 12.1 0.2 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MIF4G PF02854.14 EGO55551.1 - 2e-24 86.1 0.0 1.3e-23 83.5 0.2 2.0 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EGO55551.1 - 9e-16 57.5 0.0 4.4e-15 55.3 0.0 2.2 2 0 0 2 2 2 1 MA3 domain SRP14 PF02290.10 EGO55552.1 - 8e-21 73.7 0.4 9.8e-21 73.4 0.0 1.3 2 0 0 2 2 2 1 Signal recognition particle 14kD protein RRM_1 PF00076.17 EGO55553.1 - 4e-55 183.3 0.0 1e-18 66.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO55553.1 - 3.4e-43 145.4 0.0 5.3e-15 55.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO55553.1 - 3.2e-24 84.5 0.0 2.1e-06 27.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGO55553.1 - 3.6e-07 29.8 0.0 0.96 9.2 0.0 3.9 3 2 0 3 3 3 3 Limkain b1 RRM_3 PF08777.6 EGO55553.1 - 1.9e-06 27.6 0.0 0.63 9.9 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif ATP-grasp_2 PF08442.5 EGO55553.1 - 0.00055 19.3 0.0 0.033 13.5 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp domain COQ9 PF08511.6 EGO55558.1 - 1.3e-27 95.1 0.0 2.2e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 COQ9 SSP160 PF06933.6 EGO55558.1 - 0.039 11.9 16.4 0.054 11.4 11.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3827 PF12877.2 EGO55558.1 - 0.5 8.3 7.5 0.67 7.9 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF515 PF04415.7 EGO55558.1 - 2.7 6.1 15.0 3.5 5.7 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) CAF-1_p150 PF11600.3 EGO55558.1 - 6.2 6.1 7.0 9.3 5.5 4.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MSP1_C PF07462.6 EGO55558.1 - 6.8 4.9 7.8 9.5 4.4 5.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PAP1 PF08601.5 EGO55558.1 - 9.8 5.7 11.8 13 5.3 8.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 SMC_N PF02463.14 EGO55559.1 - 5.5e-26 91.1 0.2 1.4e-25 89.8 0.2 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGO55559.1 - 4.5e-11 43.4 43.1 4.2e-07 30.4 28.7 3.3 1 1 1 2 2 2 1 AAA domain AAA_21 PF13304.1 EGO55559.1 - 6.1e-07 29.6 3.4 0.00016 21.7 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EGO55559.1 - 0.00013 21.1 0.2 0.00013 21.1 0.1 2.5 2 1 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.1 EGO55559.1 - 0.00051 19.5 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EGO55559.1 - 0.0007 19.4 0.0 0.0023 17.8 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 EGO55559.1 - 0.002 18.4 12.0 0.042 14.1 0.0 4.0 2 1 0 2 2 2 1 ABC transporter MscS_porin PF12795.2 EGO55559.1 - 0.026 13.8 28.1 0.24 10.6 11.7 3.3 1 1 1 3 3 3 0 Mechanosensitive ion channel porin domain FlxA PF14282.1 EGO55559.1 - 0.037 13.9 19.6 0.6 10.0 0.4 3.8 3 0 0 3 3 3 0 FlxA-like protein DUF3584 PF12128.3 EGO55559.1 - 0.57 7.4 34.8 0.17 9.2 8.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.7 EGO55559.1 - 2.8 7.7 11.0 2.6 7.8 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) SGT1 PF07093.6 EGO55560.1 - 5.2e-162 540.2 42.8 8.4e-161 536.2 29.7 1.9 1 1 0 1 1 1 1 SGT1 protein DUF3439 PF11921.3 EGO55560.1 - 0.007 16.1 2.3 0.093 12.4 0.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) V-SNARE PF05008.10 EGO55560.1 - 0.094 12.8 0.4 0.094 12.8 0.3 2.6 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Peptidase_C14 PF00656.17 EGO55561.1 - 1.2e-71 241.3 0.0 1.5e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain PAT1 PF09770.4 EGO55561.1 - 0.71 8.0 19.5 1 7.5 13.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TPP_enzyme_N PF02776.13 EGO55565.1 - 6.7e-34 116.8 0.0 1e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGO55565.1 - 3e-29 101.5 0.0 1.2e-28 99.5 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EGO55565.1 - 6.9e-12 45.1 0.0 2.1e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Tox-MPTase5 PF15641.1 EGO55565.1 - 0.13 12.2 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 Metallopeptidase toxin 5 Evr1_Alr PF04777.8 EGO55566.1 - 2.1e-31 107.6 1.9 1.7e-30 104.7 0.5 2.0 2 0 0 2 2 2 1 Erv1 / Alr family HEM4 PF02602.10 EGO55567.1 - 2.3e-33 115.3 0.0 3e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TLD PF07534.11 EGO55568.1 - 5.5e-26 91.2 0.0 3.5e-15 56.2 0.0 2.3 2 0 0 2 2 2 2 TLD Pkinase PF00069.20 EGO55569.1 - 6.1e-75 251.7 0.0 8.3e-75 251.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO55569.1 - 6.9e-32 110.5 0.0 9.2e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO55569.1 - 0.0003 19.8 0.0 0.00071 18.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGO55569.1 - 0.0022 17.1 0.1 0.0037 16.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO55569.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGO55569.1 - 0.039 12.7 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.6 EGO55569.1 - 0.082 12.9 0.1 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.14 EGO55569.1 - 0.1 11.9 0.3 0.35 10.2 0.2 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain MAGE_N PF12440.3 EGO55570.1 - 0.064 13.5 1.5 0.083 13.1 1.1 1.2 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal DUF3527 PF12043.3 EGO55570.1 - 0.17 11.3 0.6 0.2 11.1 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) Sec23_trunk PF04811.10 EGO55571.1 - 1.1e-71 241.0 0.0 1.8e-71 240.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGO55571.1 - 9.6e-22 76.3 0.0 1.9e-20 72.1 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGO55571.1 - 2e-18 66.6 0.1 4.1e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGO55571.1 - 7.1e-18 63.8 5.3 1.3e-17 63.0 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGO55571.1 - 4.5e-09 35.8 0.0 1e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Pox_A28 PF04584.9 EGO55572.1 - 0.077 12.8 0.0 0.087 12.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A28 family DUF1917 PF08939.5 EGO55573.1 - 1.3e-55 188.7 0.1 1.5e-55 188.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) IF4E PF01652.13 EGO55573.1 - 0.01 15.3 0.9 0.025 14.1 0.0 2.0 3 0 0 3 3 3 0 Eukaryotic initiation factor 4E SPOR PF05036.8 EGO55573.1 - 0.073 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Sporulation related domain WD40 PF00400.27 EGO55574.1 - 0.00022 20.9 2.9 0.66 9.9 0.0 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat Xpo1 PF08389.7 EGO55575.1 - 1.9e-06 27.8 0.1 9.4e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 EGO55575.1 - 0.00028 20.7 0.0 0.0028 17.5 0.0 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain S-antigen PF05756.6 EGO55577.1 - 1.4 8.9 11.0 1.7 8.6 0.2 2.4 2 0 0 2 2 2 0 S-antigen protein BUD22 PF09073.5 EGO55577.1 - 2 7.4 14.0 0.13 11.3 1.2 3.1 3 0 0 3 3 3 0 BUD22 FAM176 PF14851.1 EGO55577.1 - 2.4 7.7 4.8 0.62 9.7 0.3 2.2 2 0 0 2 2 2 0 FAM176 family THUMP PF02926.12 EGO55578.1 - 2.7e-10 40.2 1.8 1e-08 35.2 0.1 2.5 2 0 0 2 2 2 2 THUMP domain Peptidase_C12 PF01088.16 EGO55582.1 - 4.9e-32 110.8 0.3 7.4e-29 100.4 0.0 3.2 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase, family 1 tRNA-synt_2b PF00587.20 EGO55583.1 - 8e-44 149.2 0.3 1.4e-43 148.4 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGO55583.1 - 2.4e-20 72.2 0.4 5.1e-20 71.2 0.3 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EGO55583.1 - 1.1e-12 47.6 0.0 2.4e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EGO55583.1 - 1.4e-09 37.5 0.0 3.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 TGS domain APC_15aa PF05972.6 EGO55583.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 APC 15 residue motif Pro-NT_NN PF07421.6 EGO55583.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor Transglut_core2 PF13369.1 EGO55584.1 - 1.2e-12 47.5 0.0 2.7e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 EGO55584.1 - 7.8e-08 31.9 0.7 1.8e-07 30.7 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO55584.1 - 8.1e-08 31.7 0.5 2.7e-07 30.0 0.4 2.0 1 0 0 1 1 1 1 F-box domain YccV-like PF08755.6 EGO55584.1 - 0.00011 22.0 0.3 0.0003 20.6 0.2 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Ytp1 PF10355.4 EGO55585.1 - 8.8e-115 382.5 6.5 8.8e-115 382.5 4.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EGO55585.1 - 4.6e-36 122.5 4.0 4.6e-36 122.5 2.8 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) NADH-u_ox-rdase PF10785.4 EGO55585.1 - 0.039 14.1 2.8 0.94 9.7 0.0 3.3 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Ca_hom_mod PF14798.1 EGO55585.1 - 0.15 10.9 0.1 0.91 8.4 0.0 2.0 2 0 0 2 2 2 0 Calcium homeostasis modulator Lactamase_B PF00753.22 EGO55586.1 - 2.5e-22 79.4 4.3 3.6e-22 78.9 3.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGO55586.1 - 4.8e-06 26.2 0.2 7.2e-06 25.6 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGO55586.1 - 0.0015 18.2 0.1 0.0022 17.7 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain UCH PF00443.24 EGO55587.1 - 4.6e-54 183.3 7.0 6.2e-54 182.9 4.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO55587.1 - 7.7e-35 120.7 5.4 1.1e-34 120.2 3.7 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGO55587.1 - 0.0015 18.6 0.2 0.0015 18.6 0.1 3.5 4 1 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein OrfB_Zn_ribbon PF07282.6 EGO55587.1 - 0.19 11.3 4.8 1.4 8.6 0.0 3.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 EGO55587.1 - 4.7 7.2 8.9 2.7 8.0 0.1 3.6 4 0 0 4 4 4 0 Zinc ribbon domain PCI PF01399.22 EGO55588.1 - 4.3e-11 43.0 0.0 1.2e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 PCI domain COX5A PF02284.11 EGO55588.1 - 0.041 13.8 0.2 0.095 12.6 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va NAD_binding_10 PF13460.1 EGO55589.1 - 2e-19 70.3 0.0 3.1e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGO55589.1 - 2.2e-18 66.3 0.0 3.9e-18 65.5 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EGO55589.1 - 9e-14 51.4 0.1 1.7e-13 50.5 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO55589.1 - 4.5e-10 38.6 0.1 9.4e-10 37.6 0.0 1.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGO55589.1 - 1.1e-09 37.5 0.0 9.7e-08 31.2 0.0 2.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EGO55589.1 - 0.00042 19.3 0.2 0.22 10.3 0.1 3.2 1 1 1 2 2 2 1 Male sterility protein KR PF08659.5 EGO55589.1 - 0.0008 19.1 0.0 0.58 9.7 0.0 3.5 3 1 1 4 4 4 1 KR domain adh_short PF00106.20 EGO55589.1 - 0.00082 19.3 0.0 0.013 15.4 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EGO55589.1 - 0.0036 16.2 0.0 0.0062 15.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EGO55589.1 - 0.051 12.5 0.0 0.091 11.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase ApbA PF02558.11 EGO55589.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DapB_N PF01113.15 EGO55589.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus N6-adenineMlase PF10237.4 EGO55590.1 - 1.3e-60 203.7 0.4 1.7e-60 203.3 0.3 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.10 EGO55590.1 - 0.044 13.1 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Rhomboid PF01694.17 EGO55591.1 - 3.2e-13 49.9 12.9 3.2e-13 49.9 8.9 2.0 2 0 0 2 2 2 1 Rhomboid family Rsa3 PF14615.1 EGO55592.1 - 1.7e-21 75.2 0.9 2.1e-21 74.9 0.6 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 HPS3_C PF14763.1 EGO55592.1 - 0.099 11.6 0.0 0.1 11.5 0.0 1.0 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, C-terminal Glyco_hydro_28 PF00295.12 EGO55593.1 - 4.5e-91 305.2 11.8 5.4e-91 304.9 8.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EGO55593.1 - 0.00033 20.4 32.5 0.0096 15.6 16.8 3.6 1 1 1 2 2 2 2 Right handed beta helix region Gaa1 PF04114.9 EGO55594.1 - 1.2e-102 344.2 4.5 1.6e-102 343.8 3.1 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component DUF2410 PF10307.4 EGO55595.1 - 7.7e-83 276.7 0.0 1.1e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Aconitase PF00330.15 EGO55596.1 - 4.3e-172 572.7 0.0 9.3e-172 571.6 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGO55596.1 - 1.1e-45 154.9 0.0 2.2e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.3 EGO55597.1 - 1.6e-09 37.6 1.0 2.6e-09 36.9 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGO55597.1 - 0.022 14.8 1.5 0.28 11.3 0.3 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) L31 PF09784.4 EGO55597.1 - 0.037 14.0 2.3 0.052 13.6 1.5 1.5 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 zf-met PF12874.2 EGO55597.1 - 0.047 13.9 0.7 0.078 13.2 0.5 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type RTA1 PF04479.8 EGO55598.1 - 2e-16 60.1 2.3 7.7e-16 58.2 1.6 1.7 1 1 0 1 1 1 1 RTA1 like protein DUF1275 PF06912.6 EGO55598.1 - 0.025 13.7 5.4 0.077 12.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) DUF308 PF03729.8 EGO55598.1 - 0.098 12.6 5.3 0.099 12.6 0.4 2.4 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) FmdA_AmdA PF03069.10 EGO55600.1 - 3.5e-148 493.2 0.0 4.4e-148 492.8 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.6 EGO55601.1 - 5e-06 26.1 14.7 0.00074 19.0 10.0 2.9 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.2 EGO55602.1 - 1.1e-36 125.6 0.0 3e-36 124.2 0.0 1.8 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 CBS PF00571.23 EGO55604.1 - 3.1e-22 78.0 1.2 1.4e-06 27.9 0.0 5.5 5 0 0 5 5 5 5 CBS domain HEAT_2 PF13646.1 EGO55605.1 - 9.4e-20 70.6 25.5 1.3e-08 34.9 0.2 8.6 3 3 6 9 9 9 9 HEAT repeats HEAT PF02985.17 EGO55605.1 - 6.7e-18 63.1 20.7 0.0012 18.7 0.0 11.3 12 0 0 12 12 9 6 HEAT repeat HEAT_EZ PF13513.1 EGO55605.1 - 3.9e-16 59.0 26.6 9.6e-09 35.4 0.1 9.8 7 3 2 9 9 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGO55605.1 - 7.5e-13 48.6 0.3 0.0048 17.2 0.0 7.4 4 2 3 8 8 8 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EGO55605.1 - 2.4e-10 39.7 6.6 3.5e-07 29.3 0.1 4.1 2 2 2 4 4 4 2 RNAPII transcription regulator C-terminal RIX1 PF08167.7 EGO55605.1 - 7.7e-08 32.1 0.2 0.016 14.9 0.0 5.1 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 EGO55605.1 - 3.3e-07 29.9 2.0 0.0059 15.9 0.2 5.7 3 2 3 6 6 6 2 CLASP N terminal Adaptin_N PF01602.15 EGO55605.1 - 2.3e-05 22.9 7.1 0.0021 16.4 0.5 3.6 3 1 1 4 4 4 2 Adaptin N terminal region Proteasom_PSMB PF10508.4 EGO55605.1 - 8.9e-05 20.9 0.8 0.0019 16.5 0.0 3.1 3 1 0 3 3 3 1 Proteasome non-ATPase 26S subunit CAS_CSE1 PF03378.10 EGO55605.1 - 0.00087 17.7 1.9 2.4 6.3 0.0 4.5 4 2 0 4 4 4 2 CAS/CSE protein, C-terminus Cnd1 PF12717.2 EGO55605.1 - 0.0011 18.8 5.2 2.5 7.9 0.1 4.4 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.1 EGO55605.1 - 0.004 16.6 0.4 5.1 6.5 0.0 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF4042) IBN_N PF03810.14 EGO55605.1 - 0.0082 16.0 0.1 0.11 12.4 0.0 3.2 2 1 0 2 2 2 1 Importin-beta N-terminal domain TAN PF11640.3 EGO55605.1 - 0.015 15.0 0.7 0.6 9.8 0.0 3.5 3 2 1 4 4 4 0 Telomere-length maintenance and DNA damage repair DUF3385 PF11865.3 EGO55605.1 - 0.037 13.9 1.6 20 5.0 0.0 4.7 5 1 0 5 5 5 0 Domain of unknown function (DUF3385) Cohesin_HEAT PF12765.2 EGO55605.1 - 0.062 13.2 0.1 3.2 7.7 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DRIM PF07539.7 EGO55605.1 - 0.11 11.9 1.0 0.32 10.4 0.3 2.0 2 0 0 2 2 2 0 Down-regulated in metastasis Dopey_N PF04118.9 EGO55605.1 - 0.13 10.9 2.5 0.66 8.6 0.0 3.3 4 0 0 4 4 4 0 Dopey, N-terminal V-ATPase_H_N PF03224.9 EGO55605.1 - 0.16 11.0 5.3 1 8.4 0.0 3.4 2 1 0 2 2 2 0 V-ATPase subunit H Arm PF00514.18 EGO55605.1 - 8.1 6.4 16.7 7.9 6.4 0.0 5.8 7 0 0 7 7 6 0 Armadillo/beta-catenin-like repeat PAS_9 PF13426.1 EGO55606.1 - 7.7e-32 109.7 2.8 5.5e-19 68.4 0.0 4.0 4 0 0 4 4 4 3 PAS domain PAS_3 PF08447.6 EGO55606.1 - 4.9e-21 74.6 1.4 1.5e-12 47.4 0.0 4.5 4 0 0 4 4 4 3 PAS fold GATA PF00320.22 EGO55606.1 - 7.2e-15 54.0 9.7 1.7e-14 52.8 6.7 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 EGO55606.1 - 3.8e-14 52.4 14.4 1.3e-05 24.8 0.0 5.6 5 1 0 5 5 5 3 PAS fold PAS_4 PF08448.5 EGO55606.1 - 9.6e-07 28.8 5.9 0.047 13.7 0.0 4.8 5 0 0 5 5 5 2 PAS fold PAS_8 PF13188.1 EGO55606.1 - 0.16 11.8 0.0 0.94 9.4 0.0 2.1 2 0 0 2 2 2 0 PAS domain EIIBC-GUT_N PF03612.9 EGO55606.1 - 1.4 8.5 14.4 4.9 6.7 7.2 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Bromodomain PF00439.20 EGO55608.1 - 1e-38 131.0 0.3 4.3e-18 65.0 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EGO55608.1 - 1.5e-18 66.6 1.1 3.8e-18 65.3 0.6 1.9 2 0 0 2 2 2 1 BAH domain OTU PF02338.14 EGO55609.1 - 9.3e-10 39.1 0.0 1.6e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease PB1 PF00564.19 EGO55609.1 - 0.047 13.3 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 PB1 domain Rho_Binding PF08912.6 EGO55609.1 - 0.11 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Rho Binding Mito_carr PF00153.22 EGO55610.1 - 1.4e-44 149.6 5.6 3.7e-18 65.0 0.0 4.3 3 2 0 3 3 3 3 Mitochondrial carrier protein Apt1 PF10351.4 EGO55610.1 - 0.058 12.2 0.5 0.074 11.8 0.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DEC-1_N PF04625.8 EGO55610.1 - 0.21 10.2 6.4 0.19 10.3 3.4 1.6 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Macoilin PF09726.4 EGO55610.1 - 0.49 8.6 5.9 0.64 8.2 4.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Sel1 PF08238.7 EGO55611.1 - 3.5e-18 65.5 27.0 1.5e-07 31.7 0.1 7.5 6 1 1 7 7 7 3 Sel1 repeat TPR_1 PF00515.23 EGO55611.1 - 0.004 16.7 4.9 0.032 13.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGO55611.1 - 0.0062 16.3 8.3 0.41 10.6 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGO55611.1 - 0.051 13.3 4.8 0.068 12.9 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGO55611.1 - 0.12 13.1 1.5 26 5.8 0.0 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGO55611.1 - 0.31 10.7 0.0 0.31 10.7 0.0 3.1 4 0 0 4 4 4 0 TPR repeat TPR_6 PF13174.1 EGO55611.1 - 2 9.0 0.0 2 9.0 0.0 4.4 5 1 0 5 5 5 0 Tetratricopeptide repeat SAC3_GANP PF03399.11 EGO55612.1 - 8.1e-23 81.0 0.0 1.2e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EGO55612.1 - 2.3e-18 66.3 0.0 3.8e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Coatomer_WDAD PF04053.9 EGO55613.1 - 8e-150 499.4 0.0 1.2e-149 498.8 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EGO55613.1 - 4.2e-85 285.8 0.0 6e-85 285.3 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EGO55613.1 - 3.9e-54 178.6 9.9 1.6e-09 37.2 0.0 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EGO55613.1 - 0.022 12.9 9.4 0.21 9.6 0.0 3.9 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Clathrin PF00637.15 EGO55613.1 - 0.14 11.7 0.4 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 Region in Clathrin and VPS UDP-g_GGTase PF06427.6 EGO55614.1 - 4.2e-63 212.4 0.1 2.9e-61 206.4 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EGO55614.1 - 6.9e-06 25.5 0.3 1.8e-05 24.2 0.2 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 SNF2_N PF00176.18 EGO55615.1 - 6e-67 225.5 0.0 8e-67 225.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EGO55615.1 - 2.2e-65 220.1 4.6 8.1e-65 218.2 2.9 2.0 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 EGO55615.1 - 5.1e-13 48.6 0.0 1.7e-12 46.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGO55615.1 - 2.2e-05 23.4 0.0 6.9e-05 21.8 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EGO55615.1 - 0.0038 17.0 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sec7 PF01369.15 EGO55616.1 - 2.4e-42 144.7 0.1 5.9e-42 143.4 0.1 1.6 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EGO55616.1 - 6.6e-19 68.2 0.0 1.6e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain M_domain PF12938.2 EGO55616.1 - 5.7 6.6 13.8 3.4 7.4 6.4 2.7 2 0 0 2 2 2 0 M domain of GW182 F-box-like PF12937.2 EGO55617.1 - 0.00052 19.6 0.2 0.0013 18.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like DUF1383 PF07134.6 EGO55617.1 - 0.048 12.5 0.0 0.07 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1383) DUF793 PF05633.6 EGO55617.1 - 0.83 8.3 2.2 1.4 7.6 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Glyco_hydro_61 PF03443.9 EGO55619.1 - 9.3e-52 175.9 0.0 1.1e-51 175.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Alpha-L-AF_C PF06964.7 EGO55620.1 - 2.9e-24 85.7 0.0 4.7e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus DUF2697 PF10906.3 EGO55621.1 - 0.0029 17.5 0.1 0.0045 16.9 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2697) Trypan_PARP PF05887.6 EGO55622.1 - 1.8 8.3 8.9 0.66 9.7 4.1 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF1996 PF09362.5 EGO55623.1 - 1e-87 293.6 0.2 1.3e-87 293.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TAF1_subA PF14929.1 EGO55624.1 - 0.0091 14.4 0.2 0.013 13.9 0.1 1.2 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A zf-C4_ClpX PF06689.8 EGO55625.1 - 0.055 12.9 0.1 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ClpX C4-type zinc finger NPP1 PF05630.6 EGO55626.1 - 6.5e-81 270.9 0.5 7.6e-81 270.7 0.3 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Mito_carr PF00153.22 EGO55627.1 - 5.6e-17 61.2 3.1 6.3e-12 45.0 0.0 3.7 3 1 0 3 3 3 2 Mitochondrial carrier protein DUF919 PF06034.6 EGO55627.1 - 0.028 14.0 1.0 0.061 12.9 0.7 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Glyco_transf_90 PF05686.7 EGO55628.1 - 1.2e-14 53.8 7.1 2.9e-12 46.0 1.9 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 Defensin_4 PF07936.7 EGO55628.1 - 0.1 12.3 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Potassium-channel blocking toxin MARVEL PF01284.18 EGO55629.1 - 5.1e-07 29.5 17.3 8.4e-07 28.9 11.8 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF3671 PF12420.3 EGO55629.1 - 0.33 10.9 0.0 0.33 10.9 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function CCSMST1 PF15013.1 EGO55629.1 - 6.7 6.7 8.5 10 6.1 0.9 2.5 2 0 0 2 2 2 0 CCSMST1 family Arginase PF00491.16 EGO55630.1 - 8.5e-77 258.1 0.1 9.9e-77 257.9 0.1 1.0 1 0 0 1 1 1 1 Arginase family Microtub_assoc PF07989.6 EGO55631.1 - 2.3e-19 69.0 9.0 2.3e-19 69.0 6.2 8.5 8 2 2 10 10 10 1 Microtubule associated Mto2_bdg PF12808.2 EGO55631.1 - 3.2e-10 39.9 13.6 3.2e-10 39.9 9.4 12.5 12 2 0 12 12 12 1 Micro-tubular organiser Mto1 C-term Mto2-binding region NPV_P10 PF05531.7 EGO55631.1 - 0.11 12.6 0.1 0.11 12.6 0.0 4.9 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 EGO55631.1 - 0.17 11.0 28.1 0.089 11.9 1.3 5.2 4 1 1 5 5 5 0 Reovirus sigma C capsid protein DUF1993 PF09351.5 EGO55634.1 - 5.4e-53 179.2 0.7 6.2e-53 179.0 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) AAA_22 PF13401.1 EGO55634.1 - 0.011 15.8 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Methyltransf_2 PF00891.13 EGO55635.1 - 5e-29 101.1 0.0 7.6e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase FeoC PF09012.5 EGO55635.1 - 0.045 13.4 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator Glyco_hydro_61 PF03443.9 EGO55637.1 - 6.9e-09 35.8 0.1 8e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HMG_box PF00505.14 EGO55638.1 - 8.2e-08 32.4 0.1 5.6e-07 29.7 0.1 2.2 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO55638.1 - 0.054 13.8 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 HMG-box domain DUF1143 PF06608.6 EGO55638.1 - 0.12 12.3 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) GATase PF00117.23 EGO55639.1 - 1.7e-38 132.0 0.0 3e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EGO55639.1 - 8.5e-38 127.9 0.0 1.5e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 EGO55639.1 - 4.1e-10 38.9 0.0 5.2e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EGO55639.1 - 4.7e-08 32.7 0.0 1.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 Arginosuc_synth PF00764.14 EGO55639.1 - 0.00092 18.3 0.1 0.0013 17.8 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase tRNA_Me_trans PF03054.11 EGO55639.1 - 0.0012 17.4 0.0 0.0032 16.0 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 EGO55639.1 - 0.0061 16.0 0.0 0.036 13.5 0.0 2.0 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.8 EGO55639.1 - 0.034 13.4 0.0 0.41 9.8 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.14 EGO55639.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.16 EGO55639.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase ATP_bind_3 PF01171.15 EGO55639.1 - 0.12 11.9 0.0 0.41 10.1 0.0 1.9 2 0 0 2 2 2 0 PP-loop family zf-C2H2_4 PF13894.1 EGO55641.1 - 2.5e-08 33.6 24.4 0.004 17.3 0.2 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO55641.1 - 5.7e-05 23.2 21.0 0.02 15.1 1.1 5.0 3 1 1 4 4 4 2 Zinc finger, C2H2 type TF_Zn_Ribbon PF08271.7 EGO55641.1 - 0.0025 17.1 0.1 0.016 14.4 0.0 2.4 2 0 0 2 2 2 1 TFIIB zinc-binding SprT-like PF10263.4 EGO55641.1 - 0.005 16.5 1.1 0.005 16.5 0.8 2.2 2 2 0 2 2 2 1 SprT-like family zf-met PF12874.2 EGO55641.1 - 0.013 15.6 9.9 1.8 8.8 0.2 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGO55641.1 - 0.049 13.7 8.1 0.6 10.3 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Elf1 PF05129.8 EGO55641.1 - 0.36 10.5 7.5 0.93 9.2 0.0 3.0 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like DUF629 PF04780.7 EGO55641.1 - 1.8 6.9 5.9 6.5 5.1 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF629) zf-Di19 PF05605.7 EGO55641.1 - 2.1 8.5 16.4 5.3 7.2 0.4 4.9 4 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.5 EGO55641.1 - 6 6.9 9.1 7.8 6.5 0.5 3.4 3 0 0 3 3 3 0 Zinc ribbon domain PMI_typeI PF01238.16 EGO55642.1 - 4.8e-73 246.2 0.0 7.2e-72 242.4 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 EGO55642.1 - 5.7e-06 26.0 0.0 0.00035 20.2 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.6 EGO55642.1 - 8.4e-06 25.1 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EGO55642.1 - 0.0035 16.6 1.3 0.022 14.1 0.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF861) DUF3292 PF11696.3 EGO55643.1 - 1.9e-210 700.1 0.0 1.4e-116 389.9 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) Peptidase_M1 PF01433.15 EGO55645.1 - 1.4e-131 439.2 0.1 3.1e-131 438.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 EGO55645.1 - 8.7e-75 251.9 0.0 6.3e-74 249.1 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EGO55645.1 - 8.7e-21 74.3 1.7 6.5e-20 71.4 0.1 2.5 1 1 1 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 EGO55645.1 - 0.0033 17.2 0.1 0.013 15.3 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 EGO55645.1 - 0.026 14.1 0.0 0.071 12.7 0.0 1.7 1 0 0 1 1 1 0 SprT-like family Dabb PF07876.7 EGO55647.1 - 1.9e-23 82.7 0.0 2.1e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Myb_DNA-binding PF00249.26 EGO55649.1 - 2.9e-14 52.8 7.0 4e-07 29.9 0.1 3.9 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGO55649.1 - 1.9e-11 43.8 17.9 2.6e-09 37.0 0.2 4.2 3 1 1 4 4 4 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EGO55649.1 - 3.6 7.8 9.5 0.81 9.9 0.5 4.2 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like zf-CCHC PF00098.18 EGO55652.1 - 3.6e-07 29.7 1.5 5.9e-07 29.1 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO55652.1 - 0.054 13.2 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EGO55652.1 - 0.17 11.5 0.8 0.3 10.7 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF3449 PF11931.3 EGO55653.1 - 5 6.5 5.6 2.8 7.3 1.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3449) AAA_16 PF13191.1 EGO55654.1 - 8.7e-06 25.8 1.7 0.00019 21.5 0.3 2.9 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EGO55654.1 - 0.00039 20.1 0.1 0.00059 19.5 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 EGO55654.1 - 0.022 14.1 0.3 0.41 10.0 0.0 2.5 1 1 1 2 2 2 0 AAA domain Miro PF08477.8 EGO55654.1 - 0.056 13.9 0.0 2.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein DUF815 PF05673.8 EGO55654.1 - 0.077 11.9 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Fungal_trans_2 PF11951.3 EGO55657.1 - 6.1e-32 110.6 0.0 3.4e-31 108.2 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO55657.1 - 1.7e-08 34.2 11.5 2.9e-08 33.4 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EGO55657.1 - 1.5 8.7 8.4 4.2 7.3 5.8 1.8 1 0 0 1 1 1 0 AT hook motif Pyocin_S PF06958.7 EGO55658.1 - 0.4 11.0 4.6 0.45 10.8 3.2 1.1 1 0 0 1 1 1 0 S-type Pyocin polyprenyl_synt PF00348.12 EGO55659.1 - 7.5e-55 185.5 0.1 1.2e-50 171.8 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EGO55659.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Vma12 PF11712.3 EGO55660.1 - 1.4e-40 138.3 0.0 1.9e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1358 PF07096.6 EGO55660.1 - 0.027 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) zf-C2H2_3 PF13878.1 EGO55661.1 - 4.1e-07 29.4 0.2 6.6e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO MMS19_C PF12460.3 EGO55661.1 - 0.017 13.8 0.1 0.023 13.4 0.1 1.1 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal F1F0-ATPsyn_F PF10791.4 EGO55661.1 - 0.26 11.5 1.3 0.7 10.1 0.9 1.7 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi PSDC PF12588.3 EGO55662.1 - 7.8e-49 164.9 0.0 1.2e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EGO55662.1 - 1.4e-35 122.4 0.0 2.2e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 EGO55662.1 - 0.00049 19.7 0.0 0.092 12.4 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.17 EGO55662.1 - 0.046 13.3 0.0 0.76 9.4 0.0 2.3 2 0 0 2 2 2 0 Biotin-requiring enzyme Peptidase_M23 PF01551.17 EGO55662.1 - 0.058 13.4 0.1 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M23 PTS_EIIA_1 PF00358.15 EGO55662.1 - 0.066 12.7 0.1 0.64 9.5 0.1 2.1 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.1 EGO55662.1 - 0.15 11.7 0.0 12 5.6 0.0 2.5 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Ribonuc_2-5A PF06479.7 EGO55663.1 - 0.12 12.2 5.3 0.13 12.1 2.8 1.6 2 0 0 2 2 2 0 Ribonuclease 2-5A Sld5 PF05916.6 EGO55663.1 - 2.2 8.6 5.1 0.72 10.1 0.7 2.1 2 1 0 2 2 2 0 GINS complex protein ADH_zinc_N PF00107.21 EGO55665.1 - 1.2e-25 89.5 0.0 1.8e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO55665.1 - 1.2e-07 32.6 0.2 2.9e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PhoH PF02562.11 EGO55665.1 - 0.015 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Nitr_red_assoc PF09655.5 EGO55666.1 - 0.096 13.0 0.0 8 6.7 0.0 2.1 2 0 0 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Git3_C PF11970.3 EGO55667.1 - 0.14 11.8 0.0 0.25 11.1 0.0 1.3 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term Amidohydro_1 PF01979.15 EGO55668.1 - 5.8e-20 72.2 0.7 1.7e-12 47.6 0.3 3.1 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EGO55668.1 - 6.4e-19 69.0 2.0 3.9e-15 56.6 0.3 2.6 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EGO55668.1 - 7.1e-12 44.9 0.0 1.7e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGO55668.1 - 5.1e-06 25.9 1.6 0.0018 17.5 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family PIP5K PF01504.13 EGO55669.1 - 7.6e-87 290.5 0.1 1.1e-86 290.0 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SYS1 PF09801.4 EGO55670.1 - 9.1e-50 168.4 2.1 1.1e-49 168.1 1.5 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Actino_peptide PF14408.1 EGO55670.1 - 0.03 14.2 2.4 0.065 13.1 1.6 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes COX6B PF02297.12 EGO55671.1 - 2.4e-23 81.9 6.2 3e-23 81.6 4.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EGO55671.1 - 0.054 13.5 2.0 0.12 12.4 1.4 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Acyl-CoA_dh_1 PF00441.19 EGO55673.1 - 2.1e-24 86.3 0.2 3.3e-24 85.6 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGO55673.1 - 1.9e-23 83.1 0.0 4.1e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGO55673.1 - 1.9e-16 59.2 0.0 3.9e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGO55673.1 - 2.6e-09 37.4 0.1 4.2e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UPF0547 PF10571.4 EGO55674.1 - 0.024 14.3 2.7 0.038 13.6 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 MTHFR_C PF12225.3 EGO55674.1 - 0.18 11.3 9.4 0.22 11.0 6.5 1.3 1 1 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal zf-HIT PF04438.11 EGO55674.1 - 0.85 9.3 8.5 0.33 10.6 2.0 2.5 2 1 0 2 2 2 0 HIT zinc finger zf-C2HC5 PF06221.8 EGO55674.1 - 0.91 9.3 9.5 1.8 8.4 1.0 2.3 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type RNA_POL_M_15KD PF02150.11 EGO55674.1 - 1.8 8.3 7.0 5.1 6.8 1.8 2.4 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit zinc-ribbons_6 PF07191.7 EGO55674.1 - 1.8 8.4 7.8 53 3.7 5.1 2.2 1 1 1 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.5 EGO55674.1 - 1.9 8.5 8.8 11 6.0 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 EGO55674.1 - 3.6 7.4 10.7 1.9e+02 1.9 7.4 2.4 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 EGO55674.1 - 7.4 6.2 8.4 1e+02 2.5 5.8 2.0 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family OrfB_Zn_ribbon PF07282.6 EGO55674.1 - 8.9 6.0 15.0 0.99 9.1 1.8 2.3 1 1 0 2 2 2 0 Putative transposase DNA-binding domain UQ_con PF00179.21 EGO55675.1 - 1.1e-51 173.9 0.0 1.2e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO55675.1 - 3.3e-05 23.6 0.0 3.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGO55675.1 - 0.0013 18.6 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EGO55675.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain NAD_binding_6 PF08030.7 EGO55676.1 - 2.5e-31 108.7 0.0 4.9e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGO55676.1 - 2.3e-21 75.6 0.0 6.5e-21 74.1 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGO55676.1 - 2.8e-17 62.9 18.6 1.9e-16 60.2 7.3 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGO55676.1 - 0.00015 21.8 0.0 0.00043 20.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGO55676.1 - 0.084 13.4 0.0 0.61 10.6 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain XPG_I PF00867.13 EGO55677.1 - 1.9e-31 107.9 0.6 3.2e-31 107.2 0.0 1.7 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EGO55677.1 - 2e-26 92.1 0.1 2e-26 92.1 0.0 2.0 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EGO55677.1 - 1.7e-05 24.9 1.6 9.2e-05 22.6 0.0 2.9 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold TniB PF05621.6 EGO55677.1 - 0.048 12.4 0.0 0.069 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Acyl-CoA_dh_1 PF00441.19 EGO55678.1 - 8.8e-42 142.7 0.3 1.2e-41 142.2 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGO55678.1 - 6.9e-21 73.5 0.3 1.3e-20 72.6 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EGO55678.1 - 3.4e-19 68.4 0.2 6.4e-19 67.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EGO55678.1 - 1.4e-15 57.8 0.0 3.8e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGO55678.1 - 2.8e-08 34.0 0.0 5.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_60s PF00428.14 EGO55678.1 - 0.084 13.2 4.1 0.18 12.2 2.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein RRM_1 PF00076.17 EGO55679.1 - 1.6e-07 30.8 0.0 2.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO55679.1 - 0.00011 22.1 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO55679.1 - 0.0056 16.5 0.3 0.011 15.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GNAT_acetyltr_2 PF13718.1 EGO55680.1 - 1.8e-79 265.6 0.0 3.4e-79 264.7 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EGO55680.1 - 3.7e-66 222.1 0.0 1.7e-65 219.9 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EGO55680.1 - 1.5e-40 136.7 0.0 3.6e-40 135.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EGO55680.1 - 6.4e-34 116.0 0.3 1.8e-33 114.6 0.2 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain AAA_22 PF13401.1 EGO55680.1 - 0.0012 18.9 0.1 0.12 12.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta2 PF13177.1 EGO55680.1 - 0.041 13.5 0.5 0.1 12.2 0.1 1.8 2 0 0 2 2 2 0 DNA polymerase III, delta subunit Acetyltransf_7 PF13508.1 EGO55680.1 - 0.097 12.8 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3809 PF12723.2 EGO55681.1 - 0.097 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3809) Pkinase PF00069.20 EGO55682.1 - 7.5e-70 235.0 0.0 9.1e-70 234.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO55682.1 - 7.9e-30 103.7 0.0 1e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO55682.1 - 1.2e-06 27.7 0.0 1.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO55682.1 - 0.00034 20.4 0.1 0.00057 19.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO55682.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGO55682.1 - 0.059 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PAP2 PF01569.16 EGO55683.1 - 1.1e-12 47.7 7.5 1.1e-12 47.7 5.2 1.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EGO55683.1 - 8.9e-06 25.3 7.5 2.8e-05 23.7 5.2 1.9 1 1 0 1 1 1 1 PAP2 superfamily UCH PF00443.24 EGO55684.1 - 7.5e-29 100.6 0.0 1.7e-28 99.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO55684.1 - 8.4e-11 41.8 0.7 8.2e-05 22.1 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EGO55684.1 - 4.1e-08 32.5 0.4 0.0015 17.9 0.0 2.9 3 0 0 3 3 3 2 A repeated domain in UCH-protein PUB PF09409.5 EGO55684.1 - 0.0057 16.3 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 PUB domain Tim17 PF02466.14 EGO55685.1 - 5e-11 42.7 7.8 7.3e-11 42.2 5.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family LETM1 PF07766.8 EGO55686.1 - 2.8e-07 29.8 0.1 2.4e-05 23.5 0.0 2.7 2 1 0 3 3 3 2 LETM1-like protein Ribonuc_L-PSP PF01042.16 EGO55687.1 - 5.2e-41 139.1 0.0 5.9e-41 139.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ferric_reduct PF01794.14 EGO55688.1 - 4.6e-18 65.4 9.5 4.6e-18 65.4 6.6 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EGO55688.1 - 4.1e-17 62.5 0.0 6.5e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGO55688.1 - 1.2e-07 31.5 0.0 0.0027 17.5 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EGO55688.1 - 5.7e-06 26.8 0.1 0.019 15.5 0.0 2.8 2 1 0 2 2 2 2 Oxidoreductase NAD-binding domain VanZ PF04892.7 EGO55689.1 - 7.5e-11 42.1 1.3 1e-10 41.6 0.9 1.2 1 0 0 1 1 1 1 VanZ like family PMT PF02366.13 EGO55689.1 - 0.085 12.1 3.3 0.12 11.7 2.3 1.2 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Bromodomain PF00439.20 EGO55690.1 - 1.3e-18 66.6 0.2 3.7e-18 65.2 0.1 1.8 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EGO55690.1 - 7e-09 35.2 0.0 1.7e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated SHMT PF00464.14 EGO55693.1 - 7.7e-213 706.1 0.0 9.2e-213 705.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 EGO55693.1 - 5.8e-07 28.5 0.0 1.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGO55693.1 - 8.8e-05 21.6 0.0 0.0003 19.8 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGO55693.1 - 0.0026 16.9 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Asp PF00026.18 EGO55694.1 - 8.3e-108 360.3 0.2 9.9e-108 360.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO55694.1 - 9.3e-13 48.4 0.0 5.9e-12 45.8 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO55694.1 - 3.8e-06 27.3 0.1 0.089 13.2 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EGO55694.1 - 0.00024 20.6 0.0 0.0054 16.2 0.0 2.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Alpha-amylase_C PF02806.13 EGO55694.1 - 0.033 14.3 0.1 0.22 11.7 0.0 2.3 2 1 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain BRF1 PF07741.8 EGO55695.1 - 1.4 9.2 0.0 1.4 9.2 0.0 2.9 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF155 PF02582.9 EGO55696.1 - 5.5e-45 153.4 0.0 1e-44 152.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Fusion_gly PF00523.13 EGO55696.1 - 0.041 11.9 0.3 0.059 11.4 0.2 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Bclx_interact PF08945.5 EGO55696.1 - 0.21 11.1 0.1 0.21 11.1 0.1 1.9 2 0 0 2 2 2 0 Bcl-x interacting, BH3 domain Hamartin PF04388.7 EGO55696.1 - 0.29 9.7 6.8 0.45 9.1 4.7 1.2 1 0 0 1 1 1 0 Hamartin protein RINT1_TIP1 PF04437.8 EGO55697.1 - 1.4e-102 343.8 0.0 2.1e-102 343.2 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family COG2 PF06148.6 EGO55697.1 - 0.00035 20.4 4.2 0.0016 18.3 1.9 2.9 1 1 1 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 ADIP PF11559.3 EGO55697.1 - 0.0014 18.5 5.7 0.011 15.6 4.1 2.4 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EGO55697.1 - 0.066 12.9 9.6 0.043 13.5 3.0 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4164 PF13747.1 EGO55697.1 - 0.3 11.2 13.0 0.096 12.8 3.9 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Atg14 PF10186.4 EGO55697.1 - 3.9 6.3 8.6 3.4 6.5 4.4 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Sec34 PF04136.10 EGO55698.1 - 5e-30 104.2 0.3 1e-29 103.3 0.2 1.4 1 0 0 1 1 1 1 Sec34-like family IncA PF04156.9 EGO55698.1 - 0.014 14.9 1.6 0.014 14.9 1.1 2.1 2 0 0 2 2 2 0 IncA protein Ribosomal_L32p PF01783.18 EGO55698.1 - 0.21 11.7 2.2 0.68 10.1 0.0 2.3 2 0 0 2 2 2 0 Ribosomal L32p protein family RCC1 PF00415.13 EGO55699.1 - 3.6e-32 110.3 12.3 1.4e-07 31.5 0.0 8.4 7 1 1 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGO55699.1 - 6.8e-14 51.0 22.6 6.9e-11 41.4 0.0 6.1 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat FRQ PF09421.5 EGO55701.1 - 0 1724.4 43.3 0 1724.3 30.0 1.0 1 0 0 1 1 1 1 Frequency clock protein Prefoldin PF02996.12 EGO55702.1 - 2.8e-35 120.5 0.3 4.6e-35 119.8 0.2 1.4 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EGO55702.1 - 0.011 15.5 0.1 0.011 15.5 0.1 2.8 2 1 1 3 3 3 0 Prefoldin subunit HR1 PF02185.11 EGO55702.1 - 0.02 14.6 0.4 0.081 12.6 0.0 2.1 2 0 0 2 2 2 0 Hr1 repeat RNase_H2-Ydr279 PF09468.5 EGO55702.1 - 0.22 10.6 2.5 0.34 10.0 1.7 1.3 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SlyX PF04102.7 EGO55702.1 - 1.6 9.1 5.6 21 5.5 0.1 3.3 2 1 1 3 3 3 0 SlyX Lebercilin PF15619.1 EGO55702.1 - 2.2 7.6 9.1 8.8 5.7 3.6 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CRAL_TRIO PF00650.15 EGO55703.1 - 2.8e-37 127.6 0.0 4.3e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGO55703.1 - 1.2e-09 38.1 2.9 1.9e-09 37.5 0.1 2.5 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGO55703.1 - 8.7e-05 22.4 0.0 0.00024 21.0 0.0 1.6 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Mis14 PF08641.7 EGO55704.1 - 0.00037 20.5 4.3 0.00037 20.5 3.0 2.3 2 1 1 3 3 3 1 Kinetochore protein Mis14 like SAGA-Tad1 PF12767.2 EGO55704.1 - 0.1 12.2 6.2 0.17 11.5 4.3 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Glyco_transf_15 PF01793.11 EGO55704.1 - 0.74 8.7 5.6 1.2 8.0 3.9 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Ndc1_Nup PF09531.5 EGO55704.1 - 0.87 7.9 4.0 0.97 7.7 2.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PBP_sp32 PF07222.7 EGO55704.1 - 6 5.9 9.6 7 5.7 6.1 1.4 1 1 0 1 1 1 0 Proacrosin binding protein sp32 AAA PF00004.24 EGO55706.1 - 1.8e-45 154.3 0.2 5.1e-45 152.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGO55706.1 - 8.3e-09 35.3 0.1 2.9e-08 33.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGO55706.1 - 4.8e-08 33.0 0.0 1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGO55706.1 - 5.3e-07 29.8 0.0 1.4e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO55706.1 - 8.3e-07 29.2 0.5 0.001 19.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 EGO55706.1 - 3.1e-06 26.3 0.0 6.4e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EGO55706.1 - 0.00019 21.3 0.1 0.00084 19.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGO55706.1 - 0.00036 19.6 0.0 0.00085 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EGO55706.1 - 0.00041 20.3 0.0 0.00081 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO55706.1 - 0.00058 20.6 0.1 0.0022 18.7 0.0 2.0 3 0 0 3 3 1 1 AAA domain NACHT PF05729.7 EGO55706.1 - 0.00089 18.9 0.3 0.06 13.0 0.0 2.8 2 1 0 3 3 2 1 NACHT domain TIP49 PF06068.8 EGO55706.1 - 0.0011 17.7 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 EGO55706.1 - 0.0014 17.7 0.1 0.0038 16.3 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EGO55706.1 - 0.0014 18.3 0.2 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EGO55706.1 - 0.0015 18.6 0.0 0.0038 17.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 EGO55706.1 - 0.0024 17.6 0.0 0.0089 15.7 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_23 PF13476.1 EGO55706.1 - 0.0037 17.6 0.6 0.85 9.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EGO55706.1 - 0.0038 16.8 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGO55706.1 - 0.0053 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EGO55706.1 - 0.0054 16.3 0.0 0.041 13.5 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EGO55706.1 - 0.0054 16.3 0.0 0.021 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EGO55706.1 - 0.0061 15.7 0.2 0.013 14.6 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EGO55706.1 - 0.0067 15.8 0.3 0.024 14.0 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.1 EGO55706.1 - 0.0069 15.9 0.0 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EGO55706.1 - 0.0075 15.9 0.6 0.058 13.0 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 EGO55706.1 - 0.0085 16.3 0.0 0.025 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Viral_Hsp90 PF03225.9 EGO55706.1 - 0.0085 14.4 0.0 0.013 13.8 0.0 1.2 1 0 0 1 1 1 1 Viral heat shock protein Hsp90 homologue AAA_24 PF13479.1 EGO55706.1 - 0.0096 15.5 0.5 0.03 13.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGO55706.1 - 0.013 14.9 2.2 0.07 12.5 0.1 2.6 2 1 1 3 3 3 0 AAA domain Bac_DnaA PF00308.13 EGO55706.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 EGO55706.1 - 0.028 13.5 1.3 0.45 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.21 EGO55706.1 - 0.041 13.3 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.11 EGO55706.1 - 0.042 12.6 0.0 0.13 10.9 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase Sigma54_activ_2 PF14532.1 EGO55706.1 - 0.047 13.7 0.1 0.37 10.8 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 EGO55706.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EGO55706.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Folliculin PF11704.3 EGO55707.1 - 1.6e-27 96.1 0.0 4.5e-27 94.6 0.0 1.8 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Y_phosphatase PF00102.22 EGO55709.1 - 6.3e-47 159.8 0.1 3e-36 124.9 0.0 3.1 2 1 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGO55709.1 - 0.00015 21.8 0.0 0.00034 20.6 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EGO55709.1 - 0.0014 18.1 0.0 0.0034 16.9 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CD24 PF14984.1 EGO55709.1 - 0.023 14.4 0.5 0.023 14.4 0.3 2.4 2 0 0 2 2 2 0 CD24 protein Y_phosphatase3 PF13350.1 EGO55709.1 - 0.14 12.4 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family PAP1 PF08601.5 EGO55709.1 - 4.6 6.8 12.2 0.31 10.6 0.4 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 DNA_pol_A_exo1 PF01612.15 EGO55710.1 - 4.8e-41 140.1 0.1 7.9e-41 139.4 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EGO55710.1 - 1.1e-26 92.8 0.2 4.1e-26 91.0 0.0 2.1 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 EGO55710.1 - 4.9e-14 51.7 0.0 1.1e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 HRDC domain DUF572 PF04502.8 EGO55710.1 - 0.87 8.7 34.5 1.8 7.7 23.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Nop53 PF07767.6 EGO55710.1 - 1 8.2 46.3 2.2 7.1 32.1 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Borrelia_P83 PF05262.6 EGO55710.1 - 1.5 6.9 29.1 2.6 6.2 20.2 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Gpi1 PF05024.10 EGO55711.1 - 5.6e-64 215.2 7.5 9.6e-64 214.5 5.2 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) UPF0203 PF05254.7 EGO55711.1 - 5.1e-26 90.3 4.2 1e-25 89.3 2.9 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EGO55711.1 - 2.3 8.0 4.7 4.7 7.0 0.5 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like TBCC PF07986.7 EGO55712.1 - 1.2e-32 111.8 0.0 2e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C HisKA_3 PF07730.8 EGO55712.1 - 0.13 12.6 0.1 0.34 11.2 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase Neugrin PF06413.6 EGO55712.1 - 1.3 8.8 6.2 5.1 6.8 0.3 2.5 2 1 0 2 2 2 0 Neugrin Med9 PF07544.8 EGO55713.1 - 5.6e-16 58.0 0.1 1e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 TFIIF_alpha PF05793.7 EGO55713.1 - 0.29 9.4 1.0 0.34 9.2 0.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) iPGM_N PF06415.8 EGO55714.1 - 2.6e-73 246.0 0.0 3.4e-73 245.6 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 EGO55714.1 - 7.2e-72 241.7 0.0 8.2e-72 241.6 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 EGO55714.1 - 2.9e-07 30.1 0.0 7.8e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGO55714.1 - 9.8e-07 28.2 0.0 3.5e-05 23.1 0.0 2.3 1 1 0 1 1 1 1 Sulfatase AP_endonuc_2 PF01261.19 EGO55714.1 - 0.009 15.3 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Leucyl-specific PF14795.1 EGO55714.1 - 0.1 12.4 0.1 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain ATP-synt_C PF00137.16 EGO55716.1 - 5.5e-16 58.2 11.1 1e-15 57.3 7.7 1.5 1 0 0 1 1 1 1 ATP synthase subunit C MOZ_SAS PF01853.13 EGO55717.1 - 4.3e-49 166.3 0.0 7.6e-49 165.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PPR_2 PF13041.1 EGO55718.1 - 0.093 12.7 0.0 12 6.0 0.0 3.0 3 0 0 3 3 3 0 PPR repeat family DNA_methylase PF00145.12 EGO55719.1 - 1.1e-29 103.6 0.0 2.2e-25 89.4 0.0 2.4 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase BAH PF01426.13 EGO55719.1 - 2.1e-10 40.4 0.4 0.00037 20.2 0.0 3.2 3 0 0 3 3 3 2 BAH domain Pkinase PF00069.20 EGO55721.1 - 8.6e-68 228.2 0.0 1.3e-67 227.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO55721.1 - 1.3e-41 142.4 0.0 1.8e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO55721.1 - 5.4e-09 35.4 0.0 1.5e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGO55721.1 - 0.0064 15.5 0.0 0.015 14.3 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AMP-binding PF00501.23 EGO55721.1 - 0.043 12.2 0.1 0.077 11.3 0.1 1.3 1 0 0 1 1 1 0 AMP-binding enzyme APH PF01636.18 EGO55721.1 - 0.095 12.4 4.7 1.8 8.2 0.1 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family C2 PF00168.25 EGO55722.1 - 4.2e-10 39.3 0.0 7e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF755 PF05501.6 EGO55722.1 - 2.2 8.3 11.0 8.7 6.4 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Zip PF02535.17 EGO55722.1 - 2.4 7.1 7.1 4.2 6.2 5.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Rax2 PF12768.2 EGO55723.1 - 0.0025 17.0 0.0 0.0056 15.9 0.0 1.6 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Ima1_N PF09779.4 EGO55723.1 - 0.0094 16.4 2.4 0.014 15.8 0.0 2.4 3 0 0 3 3 3 1 Ima1 N-terminal domain Ctr PF04145.10 EGO55723.1 - 0.036 14.1 0.2 5.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Ctr copper transporter family Mid2 PF04478.7 EGO55723.1 - 0.045 13.1 0.3 0.045 13.1 0.2 2.8 3 0 0 3 3 3 0 Mid2 like cell wall stress sensor PepSY_TM_3 PF13706.1 EGO55723.1 - 0.1 12.0 0.3 0.22 10.9 0.2 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix DUF2681 PF10883.3 EGO55723.1 - 0.43 10.8 0.0 0.43 10.8 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) DDHD PF02862.12 EGO55723.1 - 0.48 10.1 6.3 2.6 7.8 1.5 2.3 2 0 0 2 2 2 0 DDHD domain OPA3 PF07047.7 EGO55723.1 - 1.8 8.3 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) IncA PF04156.9 EGO55723.1 - 5.7 6.4 17.3 77 2.8 12.0 2.3 1 1 0 1 1 1 0 IncA protein Ycf1 PF05758.7 EGO55723.1 - 7.4 4.1 8.0 13 3.3 5.5 1.3 1 0 0 1 1 1 0 Ycf1 zf-RING_2 PF13639.1 EGO55724.1 - 9.4e-08 31.7 14.5 1.6e-07 31.0 10.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO55724.1 - 4.2e-06 26.6 11.1 6.5e-06 26.0 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO55724.1 - 1.5e-05 24.5 10.2 2.4e-05 23.8 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO55724.1 - 0.0001 21.8 9.6 0.00015 21.3 6.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGO55724.1 - 0.0028 17.7 12.5 0.0075 16.3 8.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 EGO55724.1 - 1.2 8.7 7.0 2.2 7.8 4.9 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Drc1-Sld2 PF11719.3 EGO55725.1 - 2e-34 119.4 8.2 2.2e-34 119.2 5.7 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein ORC6 PF05460.8 EGO55725.1 - 0.027 13.5 5.1 0.027 13.6 3.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Swi5 PF07061.6 EGO55725.1 - 0.028 14.2 1.1 0.056 13.2 0.8 1.4 1 0 0 1 1 1 0 Swi5 Drc1-Sld2 PF11719.3 EGO55726.1 - 2.4e-114 382.7 47.6 9.6e-114 380.7 33.0 1.9 1 1 0 1 1 1 1 DNA replication and checkpoint protein Swi5 PF07061.6 EGO55726.1 - 0.15 11.8 1.6 0.85 9.4 0.8 2.4 2 0 0 2 2 2 0 Swi5 Glyco_hydro_61 PF03443.9 EGO55727.1 - 8.3e-62 208.8 0.2 9.8e-62 208.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 EGO55730.1 - 8.4e-40 136.5 36.0 1.2e-39 136.0 24.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM237 PF15383.1 EGO55730.1 - 0.044 12.9 0.1 0.098 11.7 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 237 Clp1 PF06807.9 EGO55731.1 - 9e-11 41.8 0.0 6.1e-10 39.1 0.0 2.2 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EGO55731.1 - 0.0033 17.1 0.0 0.007 16.0 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EGO55731.1 - 0.035 14.9 0.0 0.11 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGO55731.1 - 0.048 13.6 0.2 0.34 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EGO55731.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_polI_A34 PF08208.6 EGO55732.1 - 3.6e-42 144.2 3.4 3.6e-42 144.2 2.3 5.8 2 1 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 Utp14 PF04615.8 EGO55732.1 - 1.5 6.9 80.5 0.11 10.6 45.6 2.2 2 0 0 2 2 2 0 Utp14 protein Glyco_hydro_47 PF01532.15 EGO55734.1 - 8.8e-169 561.9 0.2 1.2e-168 561.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.20 EGO55735.1 - 2.4e-65 220.2 0.0 2.4e-65 220.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO55735.1 - 6.9e-49 166.2 0.0 1.4e-48 165.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO55735.1 - 3e-09 36.2 0.0 2.8e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Cellulase PF00150.13 EGO55736.1 - 8.2e-13 48.1 4.1 9.3e-08 31.6 0.8 2.4 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 EGO55736.1 - 0.0012 18.0 0.1 1.1 8.3 0.0 2.2 2 0 0 2 2 2 2 Beta-galactosidase DNA_primase_S PF01896.14 EGO55737.1 - 2.6e-56 189.4 0.6 5.6e-56 188.3 0.1 1.7 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase small subunit tRNA_m1G_MT PF01746.16 EGO55738.1 - 8.9e-31 106.9 0.0 3.4e-22 78.9 0.0 2.4 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Mem_trans PF03547.13 EGO55738.1 - 0.073 11.3 0.5 0.073 11.3 0.3 1.2 1 0 0 1 1 1 0 Membrane transport protein TATR PF03430.8 EGO55738.1 - 0.45 9.0 18.7 0.63 8.6 13.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Dicty_REP PF05086.7 EGO55738.1 - 0.93 7.1 12.7 1.3 6.7 8.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ndc1_Nup PF09531.5 EGO55738.1 - 1.7 6.9 11.6 2.3 6.5 8.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MutS_V PF00488.16 EGO55739.1 - 2.6e-97 324.8 0.0 3.8e-97 324.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGO55739.1 - 6.2e-40 137.1 1.2 1.4e-39 136.0 0.9 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EGO55739.1 - 1.6e-25 89.7 0.6 4.9e-25 88.1 0.0 2.2 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.15 EGO55739.1 - 9.4e-20 70.7 0.0 5.1e-19 68.3 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EGO55739.1 - 5.8e-19 68.0 3.6 7e-19 67.7 0.4 2.8 3 0 0 3 3 3 1 MutS family domain IV AAA_22 PF13401.1 EGO55739.1 - 0.086 12.9 0.0 0.64 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ilm1 PF10311.4 EGO55740.1 - 1.8e-66 222.7 0.3 2.1e-66 222.5 0.2 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Prenyltrans PF00432.16 EGO55741.1 - 1.3e-33 114.2 8.0 4.9e-09 35.5 0.0 6.2 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGO55741.1 - 8.1e-22 77.7 0.0 4.8e-12 46.2 0.0 3.6 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGO55741.1 - 3.2e-07 30.3 0.0 0.014 15.3 0.0 4.1 3 1 0 3 3 3 2 Prenyltransferase-like Peptidase_M20 PF01546.23 EGO55742.1 - 8.4e-21 74.3 4.1 1.5e-20 73.4 2.8 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGO55742.1 - 9.6e-18 63.9 0.2 1.8e-17 63.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain IF-2B PF01008.12 EGO55743.1 - 4.2e-76 255.6 2.2 4.9e-76 255.3 1.5 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family TRAPPC10 PF12584.3 EGO55744.1 - 7e-22 77.5 0.2 1.3e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Rpn3_C PF08375.6 EGO55745.1 - 4.4e-25 87.8 1.5 1.3e-24 86.3 1.1 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EGO55745.1 - 1.9e-20 73.1 0.8 1.8e-19 69.9 0.0 2.8 4 0 0 4 4 4 1 PCI domain TPR_2 PF07719.12 EGO55745.1 - 0.0087 15.9 0.1 0.028 14.3 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TFIID_20kDa PF03847.8 EGO55746.1 - 3e-15 56.2 0.0 4.8e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DASH_Spc34 PF08657.5 EGO55749.1 - 3.5e-64 216.9 1.1 2.8e-63 213.9 0.7 1.9 1 1 0 1 1 1 1 DASH complex subunit Spc34 Herpes_BLLF1 PF05109.8 EGO55749.1 - 0.1 10.5 2.8 0.12 10.3 1.9 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF4061 PF13270.1 EGO55749.1 - 7.4 6.7 9.0 2.3 8.3 2.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4061) DSBA PF01323.15 EGO55750.1 - 3.7e-42 144.0 0.0 4.2e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EGO55750.1 - 1.8e-05 24.8 0.1 5.9e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 EGO55750.1 - 0.0081 15.9 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_2 PF13098.1 EGO55750.1 - 0.023 14.9 0.0 0.48 10.6 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Fig1 PF12351.3 EGO55751.1 - 1.3e-54 184.9 5.3 1.3e-54 184.9 3.6 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EGO55751.1 - 1.1e-09 38.2 8.1 1.9e-09 37.3 5.6 1.4 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 EGO55751.1 - 0.069 12.0 14.9 0.14 10.9 10.4 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF202 PF02656.10 EGO55751.1 - 0.18 12.0 0.0 0.18 12.0 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) NatB_MDM20 PF09797.4 EGO55752.1 - 6.7e-111 370.5 0.0 1.1e-110 369.8 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.1 EGO55752.1 - 0.12 13.0 1.9 41 5.1 0.1 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1903 PF08991.5 EGO55753.1 - 5.3e-06 26.5 3.5 7e-06 26.1 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EGO55753.1 - 0.00011 22.0 3.0 0.00021 21.1 2.1 1.5 1 1 0 1 1 1 1 CHCH domain UPF0203 PF05254.7 EGO55753.1 - 0.037 13.8 3.7 0.13 12.1 2.5 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EGO55753.1 - 0.088 12.5 4.7 0.88 9.3 3.0 2.3 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EGO55753.1 - 0.13 12.3 3.9 0.21 11.6 2.7 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 WBS_methylT PF12589.3 EGO55753.1 - 0.71 10.3 6.1 1.2 9.6 4.2 1.6 1 1 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome Glyco_hydro_76 PF03663.9 EGO55754.1 - 4.6e-139 463.9 4.1 6.7e-139 463.3 2.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF3439 PF11921.3 EGO55754.1 - 8.9 6.0 13.1 10 5.8 7.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Fungal_trans PF04082.13 EGO55756.1 - 4.7e-17 61.7 0.0 8.7e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO55756.1 - 1.1e-05 25.1 10.3 2e-05 24.4 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spore_coat_CotO PF14153.1 EGO55756.1 - 4.6 6.6 10.1 6 6.2 2.9 2.3 2 0 0 2 2 2 0 Spore coat protein CotO DUF604 PF04646.7 EGO55757.1 - 2.2e-11 43.4 0.0 4.6e-11 42.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EGO55757.1 - 5e-07 29.1 0.0 1.1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Fringe-like CVNH PF08881.5 EGO55758.1 - 1.1e-09 38.3 0.1 3.8e-05 23.8 0.0 3.2 2 1 0 2 2 2 2 CVNH domain RabGAP-TBC PF00566.13 EGO55759.1 - 3.7e-33 114.8 0.0 5.9e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FA_desaturase PF00487.19 EGO55760.1 - 1.1e-27 97.1 19.3 1.4e-27 96.7 13.4 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EGO55760.1 - 7.5e-06 26.0 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) eIF2A PF08662.6 EGO55761.1 - 3.8e-40 137.6 5.4 1.3e-38 132.6 0.4 3.8 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 EGO55761.1 - 9.3e-05 22.3 0.0 0.00025 20.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EGO55761.1 - 0.00016 21.4 0.2 1.7 8.6 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat RRM_5 PF13893.1 EGO55761.1 - 0.00016 21.4 0.0 0.00037 20.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO55761.1 - 0.0018 17.9 0.0 0.0043 16.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cpn60_TCP1 PF00118.19 EGO55762.1 - 3e-134 448.3 10.4 3.5e-134 448.0 7.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GARS_C PF02843.11 EGO55762.1 - 0.24 11.5 1.8 0.81 9.9 0.1 2.7 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain SWIB PF02201.13 EGO55764.1 - 7.7e-27 92.7 1.4 1.4e-26 91.9 0.2 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 EGO55764.1 - 1.2e-15 56.9 3.0 1.6e-15 56.6 1.2 1.9 2 0 0 2 2 2 1 DEK C terminal domain BTV_NS2 PF04514.7 EGO55764.1 - 0.37 9.6 12.5 0.55 9.0 8.6 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 zf-C3HC4_3 PF13920.1 EGO55765.1 - 3e-06 26.7 9.2 3e-06 26.7 6.4 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO55765.1 - 0.0042 16.7 12.5 0.0042 16.7 8.6 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Ribonuc_2-5A PF06479.7 EGO55766.1 - 2.6e-45 153.4 0.0 4.4e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EGO55766.1 - 3.4e-45 154.2 0.0 3e-44 151.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO55766.1 - 1.7e-23 83.0 0.0 2.6e-22 79.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGO55766.1 - 0.001 18.2 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO55766.1 - 0.0011 18.6 0.0 0.0025 17.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family PQQ PF01011.16 EGO55766.1 - 0.012 15.1 1.5 4.6 6.9 0.0 3.2 4 0 0 4 4 4 0 PQQ enzyme repeat PQQ_2 PF13360.1 EGO55766.1 - 0.018 14.4 0.0 0.047 13.1 0.0 1.6 1 1 0 1 1 1 0 PQQ-like domain YrbL-PhoP_reg PF10707.4 EGO55766.1 - 0.2 10.9 0.0 0.41 9.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cu-oxidase_3 PF07732.10 EGO55767.1 - 1.5e-42 144.0 1.2 5.5e-42 142.2 0.6 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGO55767.1 - 3e-40 136.9 3.9 1.2e-37 128.5 0.1 3.5 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EGO55767.1 - 1.1e-32 113.1 0.0 3.7e-32 111.4 0.0 1.9 1 0 0 1 1 1 1 Multicopper oxidase CRAL_TRIO PF00650.15 EGO55768.1 - 1.2e-16 60.5 0.0 1.8e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGO55768.1 - 0.00066 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Glyoxalase_2 PF12681.2 EGO55769.1 - 0.00019 21.9 0.0 0.00028 21.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Asp PF00026.18 EGO55771.1 - 5.2e-41 140.9 0.0 7.1e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO55771.1 - 3.9e-06 26.8 0.9 2.8e-05 24.1 0.2 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO55771.1 - 0.0034 17.8 0.1 0.19 12.2 0.0 3.2 2 1 0 2 2 2 1 Aspartyl protease DUF3443 PF11925.3 EGO55771.1 - 0.023 13.3 0.3 0.34 9.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3443) DPBB_1 PF03330.13 EGO55772.1 - 4.7e-12 45.7 0.2 1.3e-11 44.3 0.1 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGO55772.1 - 2.1e-06 27.4 0.2 2.7e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 EGO55772.1 - 0.066 13.2 0.1 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Cerato-platanin TauD PF02668.11 EGO55773.1 - 1.1e-35 123.5 0.2 1.4e-35 123.2 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AA_permease_2 PF13520.1 EGO55774.1 - 4e-72 243.0 34.7 5e-72 242.7 24.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO55774.1 - 4.2e-18 64.9 31.9 5.8e-18 64.4 22.1 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0233 PF06781.7 EGO55774.1 - 0.1 12.2 1.1 1.2 8.8 0.2 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) NACHT PF05729.7 EGO55775.1 - 4.9e-12 45.8 0.0 1.3e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGO55775.1 - 2.5e-08 34.1 0.2 3.6e-07 30.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGO55775.1 - 2.4e-07 30.9 0.1 1.2e-06 28.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EGO55775.1 - 0.022 13.7 0.5 0.039 12.9 0.0 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EGO55775.1 - 0.031 13.1 0.1 0.081 11.7 0.0 1.8 1 1 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EGO55775.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 EGO55775.1 - 0.061 13.2 0.1 0.78 9.6 0.1 2.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EGO55775.1 - 0.074 12.8 0.1 0.21 11.4 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.24 EGO55775.1 - 0.075 13.2 0.1 0.31 11.2 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EGO55775.1 - 0.083 12.5 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 Archaeal ATPase Torsin PF06309.6 EGO55775.1 - 0.11 12.4 0.1 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 Torsin AAA_17 PF13207.1 EGO55775.1 - 0.34 11.7 1.8 1.6 9.5 0.1 3.1 3 2 0 3 3 3 0 AAA domain TPP_enzyme_N PF02776.13 EGO55776.1 - 4.7e-37 127.1 0.2 2.5e-35 121.4 0.1 2.8 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGO55776.1 - 2.2e-24 85.7 0.0 4.7e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EGO55776.1 - 1.2e-23 83.3 0.2 2.7e-22 78.9 0.0 2.9 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fringe PF02434.11 EGO55779.1 - 2.9e-05 23.3 1.5 0.0003 20.0 1.1 2.2 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 EGO55779.1 - 0.046 13.3 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 Galactosyltransferase Oxysterol_BP PF01237.13 EGO55780.1 - 2.5e-74 249.8 0.0 3.3e-74 249.5 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Sugar_tr PF00083.19 EGO55782.1 - 4.8e-98 328.6 30.7 6.2e-98 328.2 21.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO55782.1 - 1.7e-23 82.9 35.4 1.4e-21 76.6 12.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGO55782.1 - 0.03 12.7 0.2 0.03 12.7 0.1 4.0 2 2 2 4 4 4 0 MFS/sugar transport protein SAD_SRA PF02182.12 EGO55783.1 - 1.3e-18 66.7 0.0 2.2e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain Med12-LCEWAV PF12145.3 EGO55783.1 - 0.015 13.8 0.2 0.023 13.1 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Herpes_U47 PF05467.6 EGO55783.1 - 0.58 7.9 3.0 0.82 7.4 2.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 FAD_binding_2 PF00890.19 EGO55784.1 - 1.7e-90 303.9 0.0 1.9e-90 303.7 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGO55784.1 - 7.2e-07 29.1 0.0 3.6e-06 26.8 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO55784.1 - 6e-05 23.0 0.0 0.051 13.4 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO55784.1 - 0.00037 20.2 0.0 0.00072 19.3 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 EGO55784.1 - 0.0012 17.8 0.0 0.0077 15.1 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGO55784.1 - 0.002 17.2 0.0 0.0053 15.8 0.0 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EGO55784.1 - 0.0081 14.6 2.7 0.12 10.7 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 EGO55784.1 - 0.011 14.5 0.0 0.024 13.5 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EGO55784.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EGO55784.1 - 0.052 12.4 0.0 0.093 11.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD-oxidase_C PF02913.14 EGO55786.1 - 4.5e-60 203.0 0.0 8.3e-60 202.1 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGO55786.1 - 1e-39 135.2 0.0 1.8e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 EGO55786.1 - 0.045 12.2 0.0 0.077 11.4 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Glyco_hydro_76 PF03663.9 EGO55787.1 - 1.3e-144 482.1 6.6 1.7e-144 481.8 4.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 p450 PF00067.17 EGO55788.1 - 2.4e-66 224.1 0.0 3e-64 217.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 CBM_19 PF03427.8 EGO55789.1 - 0.034 13.9 7.1 0.039 13.7 4.9 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) zf-Apc11 PF12861.2 EGO55790.1 - 2.4 8.0 5.1 2.9 7.7 0.7 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Alpha-amylase PF00128.19 EGO55791.1 - 8.7e-70 235.6 0.7 1.3e-69 235.0 0.5 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EGO55791.1 - 9.7e-25 86.4 0.5 3e-24 84.9 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) DUF187 PF02638.10 EGO55791.1 - 0.002 17.0 2.6 0.019 13.8 0.6 2.7 2 1 0 2 2 2 1 Glycosyl hydrolase like GH101 hDGE_amylase PF14701.1 EGO55791.1 - 0.015 14.2 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Aminotran_5 PF00266.14 EGO55791.1 - 0.1 11.2 0.1 0.23 10.1 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Alpha-amylase PF00128.19 EGO55792.1 - 7.7e-22 78.0 3.8 3.8e-19 69.2 1.8 2.9 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EGO55792.1 - 3e-18 66.1 0.4 5.5e-18 65.3 0.3 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EGO55792.1 - 2e-08 33.8 0.0 4.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGO55792.1 - 6.8e-06 26.2 0.0 1.9e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.1 EGO55792.1 - 0.043 14.4 0.4 0.18 12.4 0.3 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain Pro_CA PF00484.14 EGO55793.1 - 2e-49 167.5 0.0 2.7e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase zf-C2H2 PF00096.21 EGO55794.1 - 1.5e-19 69.0 20.8 0.013 15.7 0.3 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO55794.1 - 7.1e-19 66.6 23.6 0.002 18.3 0.1 6.1 6 0 0 6 6 6 6 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGO55794.1 - 3e-12 46.1 22.7 0.00028 21.0 0.4 5.9 6 0 0 6 6 5 4 Zinc-finger double domain zf-C2H2_6 PF13912.1 EGO55794.1 - 3.6e-12 45.7 17.6 0.0056 16.5 0.0 6.5 6 1 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO55794.1 - 5.8e-12 45.3 20.0 0.0048 16.9 0.1 6.1 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGO55794.1 - 1.7e-07 31.2 22.7 0.14 12.3 0.4 5.9 2 2 2 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EGO55794.1 - 3.2e-06 27.1 17.1 0.82 9.9 0.0 5.9 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EGO55794.1 - 0.0013 18.3 16.0 1.1 8.9 0.4 5.4 5 0 0 5 5 5 1 zinc-finger of a C2HC-type zf-DNL PF05180.7 EGO55794.1 - 0.0023 17.5 1.1 0.0023 17.5 0.8 3.4 2 2 2 4 4 4 1 DNL zinc finger zf-DNA_Pol PF08996.5 EGO55794.1 - 0.0068 15.7 10.8 0.3 10.4 0.3 3.0 2 1 1 3 3 3 2 DNA Polymerase alpha zinc finger zf-Di19 PF05605.7 EGO55794.1 - 0.0083 16.2 17.9 0.076 13.1 1.9 4.3 4 1 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1595 PF12760.2 EGO55794.1 - 0.044 13.5 17.9 0.071 12.9 0.5 4.0 4 1 0 4 4 4 0 Transposase zinc-ribbon domain zf-H2C2_5 PF13909.1 EGO55794.1 - 0.059 13.6 0.2 0.059 13.6 0.2 4.8 5 1 0 5 5 4 0 C2H2-type zinc-finger domain DZR PF12773.2 EGO55794.1 - 0.16 11.7 20.9 6.2 6.7 2.3 4.5 2 2 1 3 3 3 0 Double zinc ribbon OSTMP1 PF09777.4 EGO55794.1 - 0.76 8.8 13.4 9 5.3 0.1 2.6 1 1 1 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor HypA PF01155.14 EGO55794.1 - 0.8 9.4 13.7 3.3 7.4 0.2 3.1 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family Elf1 PF05129.8 EGO55794.1 - 1.8 8.3 18.9 4 7.2 1.0 4.1 1 1 4 5 5 5 0 Transcription elongation factor Elf1 like C1_1 PF00130.17 EGO55794.1 - 2.6 7.8 13.9 4.7 7.0 0.7 3.9 3 2 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LIM PF00412.17 EGO55794.1 - 4.1 7.5 20.8 0.71 9.9 1.7 3.9 2 2 2 4 4 4 0 LIM domain SprT-like PF10263.4 EGO55794.1 - 4.4 6.9 12.4 6.5 6.3 2.1 3.1 1 1 2 3 3 3 0 SprT-like family zinc_ribbon_5 PF13719.1 EGO55794.1 - 8.2 6.1 15.0 8 6.1 0.6 4.5 4 1 0 4 4 4 0 zinc-ribbon domain DUF3176 PF11374.3 EGO55795.1 - 1.6e-30 105.2 0.0 3.1e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) SOG2 PF10428.4 EGO55795.1 - 0.91 8.0 6.6 1.3 7.5 4.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MutS_V PF00488.16 EGO55796.1 - 7.6e-81 270.9 0.0 1.3e-80 270.2 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGO55796.1 - 1.9e-52 178.0 0.1 3.5e-52 177.1 0.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EGO55796.1 - 3.4e-33 114.0 0.1 8.5e-33 112.7 0.0 1.7 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 EGO55796.1 - 5.2e-15 55.7 0.3 2.7e-14 53.3 0.0 2.3 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EGO55796.1 - 1.3e-13 50.9 0.5 2.5e-13 50.0 0.3 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 EGO55796.1 - 0.0082 16.4 1.9 0.022 15.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGO55796.1 - 0.014 14.9 0.0 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EGO55796.1 - 0.06 11.9 0.4 1 7.8 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_21 PF13304.1 EGO55796.1 - 0.14 12.1 0.1 0.39 10.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain DUF2638 PF10937.3 EGO55798.1 - 8.9e-40 136.1 0.3 1.1e-39 135.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) Cyto_heme_lyase PF01265.12 EGO55799.1 - 1.4e-87 293.6 1.1 3.5e-87 292.2 0.7 1.5 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase NUDE_C PF04880.8 EGO55799.1 - 0.75 10.1 6.4 1.1 9.5 4.4 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region TMEM61 PF15105.1 EGO55799.1 - 1 8.8 7.4 0.78 9.2 3.8 1.7 1 1 1 2 2 2 0 TMEM61 protein family PAT1 PF09770.4 EGO55799.1 - 9.2 4.3 10.1 10 4.1 7.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF647 PF04884.9 EGO55800.1 - 1.1e-91 306.5 0.7 1.3e-91 306.2 0.5 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Mu-like_Com PF10122.4 EGO55800.1 - 0.003 16.5 0.0 0.0056 15.7 0.0 1.4 1 0 0 1 1 1 1 Mu-like prophage protein Com GHMP_kinases_N PF00288.21 EGO55801.1 - 6.3e-10 38.9 3.3 2.7e-09 36.9 0.9 2.5 2 0 0 2 2 2 1 GHMP kinases N terminal domain MFS_1 PF07690.11 EGO55804.1 - 1.4e-16 60.1 13.8 1.4e-16 60.1 9.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Hemerythrin PF01814.18 EGO55804.1 - 1.3e-06 28.6 6.1 2.4e-06 27.7 4.2 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain CoA_trans PF01144.18 EGO55805.1 - 7.6e-77 257.3 0.4 1.6e-40 138.6 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EGO55805.1 - 0.00031 20.4 0.2 0.0006 19.5 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CBP PF12192.3 EGO55806.1 - 0.043 13.7 1.7 0.14 12.1 1.2 1.8 1 0 0 1 1 1 0 Fungal calcium binding protein E1-E2_ATPase PF00122.15 EGO55807.1 - 3.4e-62 209.4 7.1 8.6e-62 208.1 4.9 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGO55807.1 - 3.9e-33 114.4 0.9 3.9e-33 114.4 0.6 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGO55807.1 - 8.1e-28 98.3 1.3 1.3e-26 94.3 0.1 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGO55807.1 - 7.4e-17 60.5 1.5 7.7e-17 60.5 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EGO55807.1 - 1.3e-15 57.1 0.0 2.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGO55807.1 - 5.7e-13 49.4 0.1 2.1e-12 47.6 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGO55807.1 - 3.2e-06 26.9 1.7 0.0002 21.0 0.5 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Nucleos_tra2_C PF07662.8 EGO55808.1 - 2.8e-71 239.3 2.4 2.8e-71 239.3 1.7 2.1 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EGO55808.1 - 1.7e-22 79.5 1.4 1.7e-22 79.5 1.0 2.8 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus ATP1G1_PLM_MAT8 PF02038.11 EGO55808.1 - 0.25 10.3 2.7 0.68 8.9 1.9 1.7 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family PNK3P PF08645.6 EGO55811.1 - 7.7e-56 187.9 0.0 1.2e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EGO55811.1 - 1.1e-31 109.6 0.0 5.6e-31 107.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGO55811.1 - 4.5e-05 22.6 0.0 0.052 12.6 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin KTI12 PF08433.5 EGO55811.1 - 0.0017 17.5 0.2 0.27 10.3 0.0 2.3 1 1 0 2 2 2 2 Chromatin associated protein KTI12 AAA_17 PF13207.1 EGO55811.1 - 0.0073 17.1 0.2 0.059 14.1 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO55811.1 - 0.054 13.8 0.3 4.3 7.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 EGO55811.1 - 0.083 12.4 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EGO55811.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGO55811.1 - 0.16 12.1 0.0 0.74 9.9 0.0 1.8 1 1 1 2 2 2 0 AAA domain Sugar_tr PF00083.19 EGO55812.1 - 4e-106 355.3 22.7 4.6e-106 355.0 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO55812.1 - 2.6e-26 92.1 45.3 2.7e-22 78.9 14.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 EGO55812.1 - 0.002 16.9 0.5 0.0046 15.6 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF791) PhoD PF09423.5 EGO55813.1 - 3.3e-154 513.8 1.2 3.9e-154 513.5 0.9 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Abhydrolase_6 PF12697.2 EGO55816.1 - 1.1e-14 54.9 0.4 1.4e-14 54.5 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO55816.1 - 0.00044 20.0 0.0 0.00065 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family SR-25 PF10500.4 EGO55816.1 - 0.25 10.7 8.8 0.42 10.0 6.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ycf1 PF05758.7 EGO55817.1 - 0.36 8.5 3.1 0.49 8.0 2.1 1.3 1 0 0 1 1 1 0 Ycf1 DSPc PF00782.15 EGO55818.1 - 7.9e-18 64.3 0.0 9.6e-11 41.3 0.0 3.1 1 1 1 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGO55818.1 - 0.023 14.0 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EGO55818.1 - 0.068 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF866 PF05907.8 EGO55818.1 - 0.17 11.3 0.1 0.27 10.6 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zf-C2H2_4 PF13894.1 EGO55819.1 - 2.3e-06 27.5 17.5 0.09 13.1 0.5 4.9 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO55819.1 - 0.0049 17.1 23.0 0.076 13.3 0.6 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-CHCC PF10276.4 EGO55819.1 - 0.048 13.5 2.8 1.9 8.3 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger domain Rtt106 PF08512.7 EGO55821.1 - 5.1e-26 90.4 0.0 2.1e-25 88.5 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Cwf_Cwc_15 PF04889.7 EGO55821.1 - 2.6 7.6 18.0 4.8 6.8 12.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Lyase_1 PF00206.15 EGO55822.1 - 6.9e-91 304.6 0.0 1e-90 304.1 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EGO55822.1 - 7.7e-28 96.3 0.0 1.9e-27 95.0 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Vfa1 PF08432.5 EGO55823.1 - 4.4e-63 212.6 25.7 4.9e-63 212.4 17.8 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF2252 PF10009.4 EGO55823.1 - 0.036 12.9 4.1 0.044 12.6 2.9 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF262 PF03235.9 EGO55823.1 - 0.041 13.8 7.4 0.063 13.2 5.2 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF262 DUF1510 PF07423.6 EGO55823.1 - 0.13 11.5 27.2 0.18 11.1 18.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TraH_2 PF06871.6 EGO55823.1 - 0.17 11.3 2.9 0.2 11.0 2.0 1.1 1 0 0 1 1 1 0 TraH_2 CDC45 PF02724.9 EGO55823.1 - 0.23 9.4 24.2 0.28 9.1 16.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF755 PF05501.6 EGO55823.1 - 0.34 10.9 15.7 0.73 9.8 10.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF2457 PF10446.4 EGO55823.1 - 0.35 9.5 23.6 0.51 8.9 16.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FLO_LFY PF01698.11 EGO55823.1 - 0.38 9.5 11.0 0.47 9.2 7.6 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Ycf1 PF05758.7 EGO55823.1 - 0.41 8.3 18.0 0.45 8.1 12.5 1.0 1 0 0 1 1 1 0 Ycf1 Pox_Ag35 PF03286.9 EGO55823.1 - 0.67 9.4 21.0 1 8.8 14.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF913 PF06025.7 EGO55823.1 - 0.82 8.3 2.9 0.94 8.1 2.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Mem_trans PF03547.13 EGO55823.1 - 0.94 7.6 5.1 0.96 7.6 3.6 1.2 1 0 0 1 1 1 0 Membrane transport protein TP53IP5 PF15331.1 EGO55823.1 - 1.6 8.6 15.3 2.1 8.1 10.6 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 RNA_polI_A34 PF08208.6 EGO55823.1 - 1.6 8.3 31.4 2.8 7.5 21.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Paramyxo_ncap PF00973.14 EGO55823.1 - 1.9 7.0 7.0 2.1 6.9 4.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Astro_capsid PF03115.9 EGO55823.1 - 1.9 6.6 5.9 1.8 6.7 4.1 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor PIN_3 PF13470.1 EGO55823.1 - 3.2 8.4 5.6 2 9.0 2.2 1.8 2 0 0 2 2 1 0 PIN domain DUF2201_N PF13203.1 EGO55823.1 - 3.3 6.7 11.8 4 6.5 8.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain MIP-T3 PF10243.4 EGO55823.1 - 3.5 5.9 35.8 4.3 5.6 24.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2413 PF10310.4 EGO55823.1 - 3.6 6.2 19.7 4.3 6.0 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) U79_P34 PF03064.11 EGO55823.1 - 4.4 6.7 22.4 6 6.3 15.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RP-C_C PF11800.3 EGO55823.1 - 4.8 6.8 11.2 6 6.5 7.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region BTV_NS2 PF04514.7 EGO55823.1 - 5.9 5.6 19.2 8.2 5.1 13.3 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 GCD14 PF08704.5 EGO55823.1 - 6.2 6.2 8.1 8.7 5.7 5.6 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit POX PF07526.6 EGO55823.1 - 6.4 6.9 11.4 11 6.2 7.9 1.4 1 0 0 1 1 1 0 Associated with HOX Menin PF05053.8 EGO55823.1 - 6.6 4.7 8.6 7.5 4.5 5.9 1.1 1 0 0 1 1 1 0 Menin Zip PF02535.17 EGO55823.1 - 6.6 5.6 5.3 7.6 5.4 3.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.11 EGO55823.1 - 6.6 6.0 19.5 12 5.2 13.5 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 Sporozoite_P67 PF05642.6 EGO55823.1 - 9 4.0 16.1 11 3.6 11.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen adh_short PF00106.20 EGO55825.1 - 1.8e-14 54.0 0.0 5e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGO55825.1 - 5.5e-05 22.8 0.1 9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EGO55825.1 - 0.021 14.9 0.1 0.062 13.3 0.0 1.7 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase ATP-grasp_5 PF13549.1 EGO55825.1 - 0.097 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain BCCT PF02028.12 EGO55826.1 - 0.00018 19.8 0.1 0.00029 19.2 0.1 1.3 1 0 0 1 1 1 1 BCCT family transporter Herpes_capsid PF06112.6 EGO55826.1 - 0.22 11.5 5.2 0.34 10.9 3.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF3720 PF12517.3 EGO55826.1 - 0.73 10.5 4.0 0.15 12.7 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) DUF607 PF04678.8 EGO55827.1 - 1.8e-42 145.3 3.4 4.8e-42 143.9 0.1 2.8 2 1 0 2 2 2 1 Protein of unknown function, DUF607 HXXSHH PF07586.6 EGO55827.1 - 0.041 12.8 2.1 0.097 11.5 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1552) Acetyltransf_8 PF13523.1 EGO55828.1 - 9.3e-38 129.4 0.3 1.5e-37 128.7 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CVNH PF08881.5 EGO55829.1 - 2e-12 47.2 0.8 3e-12 46.6 0.5 1.3 1 0 0 1 1 1 1 CVNH domain Hom_end_hint PF05203.11 EGO55830.1 - 0.00037 20.2 0.1 0.00037 20.2 0.0 1.2 1 0 0 1 1 1 1 Hom_end-associated Hint TFIIA PF03153.8 EGO55830.1 - 0.00075 19.5 26.1 0.0014 18.6 18.1 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 EGO55830.1 - 0.0014 16.9 53.3 0.0019 16.5 36.9 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4457 PF14652.1 EGO55830.1 - 0.071 12.0 0.0 0.071 12.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4457) SAGA-Tad1 PF12767.2 EGO55830.1 - 0.14 11.7 19.6 0.25 10.9 13.6 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AvrE PF11725.3 EGO55830.1 - 0.52 7.2 16.8 0.83 6.6 11.6 1.2 1 0 0 1 1 1 0 Pathogenicity factor PAT1 PF09770.4 EGO55830.1 - 0.74 7.9 53.1 0.92 7.6 36.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDRGK PF09756.4 EGO55830.1 - 9.9 5.5 17.0 16 4.8 11.8 1.3 1 0 0 1 1 1 0 DDRGK domain ABM PF03992.11 EGO55831.1 - 4.2e-06 26.7 0.0 4.5e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase OPT PF03169.10 EGO55832.1 - 9.4e-149 496.7 51.6 1.1e-148 496.5 35.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MARVEL PF01284.18 EGO55834.1 - 0.0014 18.4 19.1 0.0022 17.8 13.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 EGO55834.1 - 0.015 14.9 16.7 0.092 12.4 8.1 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling UNC-50 PF05216.8 EGO55834.1 - 0.015 14.4 2.6 0.015 14.4 1.8 1.8 2 0 0 2 2 2 0 UNC-50 family Hepatitis_core PF00906.15 EGO55834.1 - 0.025 14.2 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Hepatitis core antigen MgtE PF01769.11 EGO55834.1 - 0.12 12.6 5.0 0.15 12.3 2.0 1.9 2 0 0 2 2 2 0 Divalent cation transporter Chorion_2 PF03964.10 EGO55834.1 - 0.51 10.9 5.6 0.8 10.2 3.9 1.2 1 0 0 1 1 1 0 Chorion family 2 DUF4282 PF14110.1 EGO55834.1 - 0.78 9.9 7.1 0.56 10.4 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) DUF3671 PF12420.3 EGO55834.1 - 2.2 8.2 4.9 17 5.4 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function Cytochrom_B_C PF00032.12 EGO55834.1 - 2.6 8.3 9.8 0.84 9.9 1.9 2.6 1 1 2 3 3 3 0 Cytochrome b(C-terminal)/b6/petD DUF3176 PF11374.3 EGO55836.1 - 2.5e-23 82.0 0.0 1e-22 80.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3176) FAD_binding_3 PF01494.14 EGO55837.1 - 2.8e-19 69.3 3.0 1.1e-11 44.3 0.2 2.6 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EGO55837.1 - 5.8e-06 26.2 0.2 1.6e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO55837.1 - 0.00016 20.7 0.7 0.2 10.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO55837.1 - 0.0021 16.9 0.1 0.0028 16.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EGO55837.1 - 0.0034 17.2 0.0 0.0096 15.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO55837.1 - 0.0058 17.0 0.1 0.076 13.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO55837.1 - 0.015 15.3 0.0 0.038 14.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO55837.1 - 0.038 13.0 0.1 0.066 12.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family SE PF08491.5 EGO55837.1 - 0.049 12.4 0.0 0.84 8.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Lycopene_cycl PF05834.7 EGO55837.1 - 0.061 12.2 0.1 0.27 10.1 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EGO55837.1 - 0.067 13.2 0.1 1 9.4 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Zn_clus PF00172.13 EGO55838.1 - 1.4e-08 34.4 10.6 2.2e-08 33.8 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGO55838.1 - 0.06 12.2 1.9 0.089 11.6 0.2 2.2 2 1 0 2 2 2 0 Fungal specific transcription factor domain FliG_C PF01706.11 EGO55838.1 - 0.19 11.7 0.2 0.45 10.4 0.1 1.6 1 0 0 1 1 1 0 FliG C-terminal domain Clr5 PF14420.1 EGO55839.1 - 2.2e-18 65.8 6.6 5.3e-17 61.4 3.5 2.4 2 0 0 2 2 2 2 Clr5 domain TPR_12 PF13424.1 EGO55839.1 - 0.00011 22.0 1.1 0.00094 19.0 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Cu_bind_like PF02298.12 EGO55841.1 - 0.1 12.4 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 Plastocyanin-like domain NUP PF06516.6 EGO55843.1 - 4.3e-120 400.2 0.1 5.1e-120 400.0 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Pkinase PF00069.20 EGO55844.1 - 2e-43 148.4 0.0 5.2e-43 147.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO55844.1 - 8.6e-30 103.6 0.0 1.2e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO55844.1 - 0.0053 15.7 0.0 0.0087 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGO55844.1 - 0.032 13.3 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pectate_lyase PF03211.8 EGO55845.1 - 2.2e-72 242.9 5.2 2.9e-72 242.5 3.6 1.0 1 0 0 1 1 1 1 Pectate lyase Pkinase PF00069.20 EGO55846.1 - 7.2e-09 35.1 0.0 0.024 13.8 0.0 3.7 3 1 0 3 3 3 3 Protein kinase domain Sugar_tr PF00083.19 EGO55847.1 - 7.6e-112 374.1 29.7 5e-106 354.9 15.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EGO55847.1 - 2.2e-18 66.0 36.3 2.2e-18 66.0 25.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Foamy_BEL PF03274.9 EGO55848.1 - 0.024 13.8 0.2 0.031 13.5 0.1 1.1 1 0 0 1 1 1 0 Foamy virus BEL 1/2 protein Tyrosinase PF00264.15 EGO55849.1 - 5e-48 164.1 0.0 6.3e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase HET PF06985.6 EGO55850.1 - 0.0016 18.6 0.9 0.35 11.0 0.5 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) STE2 PF02116.10 EGO55851.1 - 8.2e-34 116.9 18.0 1.1e-33 116.4 12.4 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR CN_hydrolase PF00795.17 EGO55852.1 - 9.5e-23 80.5 0.0 2.2e-22 79.2 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Peptidase_M4_C PF02868.10 EGO55853.1 - 7.2e-31 107.1 0.1 1.3e-30 106.3 0.1 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.13 EGO55853.1 - 2.7e-10 40.5 7.3 3.5e-09 36.9 1.8 3.3 2 1 0 2 2 2 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M13 PF01431.16 EGO55853.1 - 0.93 8.6 3.3 1.4 8.0 0.9 2.2 2 1 0 2 2 2 0 Peptidase family M13 Peptidase_C97 PF05903.9 EGO55854.1 - 6.4e-20 71.4 0.0 8.5e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EGO55854.1 - 0.27 11.1 2.5 1.2 9.1 0.1 2.3 1 1 1 2 2 2 0 Lecithin retinol acyltransferase UEV PF05743.8 EGO55856.1 - 3.1e-36 123.6 0.1 5.2e-36 122.9 0.1 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EGO55856.1 - 1.5e-22 78.9 0.0 2.5e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Vps23 core domain HAUS-augmin3 PF14932.1 EGO55856.1 - 0.85 8.7 4.7 1.3 8.1 3.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 IDO PF01231.13 EGO55857.1 - 2.1e-173 576.6 0.0 2.4e-173 576.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Lipase_GDSL PF00657.17 EGO55858.1 - 4.9e-16 59.2 0.0 6.6e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EGO55858.1 - 5e-13 49.5 0.1 7.5e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EGO55858.1 - 0.0019 17.9 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cauli_VI PF01693.11 EGO55859.1 - 3.1e-34 116.7 11.4 7.6e-18 64.2 1.5 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EGO55859.1 - 9.4e-27 93.9 0.1 2e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 RNase H COX6B PF02297.12 EGO55859.1 - 0.015 15.3 0.4 0.031 14.2 0.3 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb SWI-SNF_Ssr4 PF08549.5 EGO55860.1 - 0.0027 16.0 3.9 0.0039 15.5 2.7 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) FoP_duplication PF13865.1 EGO55860.1 - 0.0097 16.3 2.2 0.011 16.1 0.1 2.0 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Serglycin PF04360.7 EGO55860.1 - 0.053 13.2 0.4 0.082 12.6 0.3 1.4 1 0 0 1 1 1 0 Serglycin Rhomboid PF01694.17 EGO55860.1 - 0.056 13.4 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 Rhomboid family DUF1212 PF06738.7 EGO55861.1 - 0.066 12.6 4.6 0.1 12.0 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) SirB PF04247.7 EGO55861.1 - 0.39 10.4 4.4 0.7 9.6 3.0 1.3 1 0 0 1 1 1 0 Invasion gene expression up-regulator, SirB HLH PF00010.21 EGO55865.1 - 3.7e-07 29.7 1.8 8.8e-07 28.5 1.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ferritin-like PF12902.2 EGO55865.1 - 0.01 15.4 1.5 0.013 15.0 1.0 1.3 1 0 0 1 1 1 0 Ferritin-like bZIP_1 PF00170.16 EGO55865.1 - 3.2 7.7 8.8 0.72 9.8 2.2 2.3 2 0 0 2 2 2 0 bZIP transcription factor SLX9 PF15341.1 EGO55865.1 - 6.4 7.2 11.3 13 6.2 7.8 1.5 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 PspB PF06667.7 EGO55865.1 - 7.5 6.5 5.8 20 5.2 0.1 2.3 2 0 0 2 2 2 0 Phage shock protein B Methyltransf_18 PF12847.2 EGO55866.1 - 2.4e-13 50.6 0.0 3.5e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO55866.1 - 3e-12 46.8 0.0 5.5e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO55866.1 - 3.1e-12 46.3 0.0 4.1e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO55866.1 - 2.7e-10 40.6 0.0 3.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO55866.1 - 3.3e-10 39.9 0.0 4.5e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO55866.1 - 9.7e-10 38.5 0.0 1.5e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGO55866.1 - 1.5e-06 27.8 0.0 2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EGO55866.1 - 1.7e-06 28.2 0.0 2.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO55866.1 - 2.5e-06 26.9 0.1 6e-06 25.7 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 EGO55866.1 - 2.9e-05 23.3 0.0 4.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB adh_short PF00106.20 EGO55866.1 - 0.00015 21.7 0.0 0.00022 21.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DUF938 PF06080.7 EGO55866.1 - 0.00042 19.9 0.0 0.00065 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PrmA PF06325.8 EGO55866.1 - 0.0039 16.3 0.0 0.0056 15.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EGO55866.1 - 0.006 15.7 0.0 0.0097 15.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.6 EGO55866.1 - 0.031 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) ADH_zinc_N PF00107.21 EGO55866.1 - 0.053 13.0 0.1 0.26 10.8 0.1 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DREV PF05219.7 EGO55866.1 - 0.13 11.0 0.1 0.4 9.5 0.0 1.9 1 1 1 2 2 2 0 DREV methyltransferase Hce2 PF14856.1 EGO55867.1 - 6.8e-08 32.3 0.0 1.9e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Abhydrolase_2 PF02230.11 EGO55868.1 - 0.00043 19.7 0.3 0.0018 17.7 0.1 2.0 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Mak10 PF04112.8 EGO55868.1 - 0.047 12.9 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase GRP PF07172.6 EGO55869.1 - 0.0019 18.6 10.5 0.0019 18.6 7.3 4.6 2 1 0 2 2 2 1 Glycine rich protein family DUF3328 PF11807.3 EGO55870.1 - 1.4e-37 129.4 2.2 1.7e-37 129.2 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Tyrosinase PF00264.15 EGO55871.1 - 6.3e-36 124.6 1.5 6.3e-36 124.6 1.0 1.6 2 0 0 2 2 2 1 Common central domain of tyrosinase SR-25 PF10500.4 EGO55871.1 - 0.005 16.3 4.7 0.005 16.3 3.3 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 EGO55871.1 - 2.4 7.4 8.6 3.8 6.8 5.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3328 PF11807.3 EGO55873.1 - 1e-30 107.0 0.1 1.8e-30 106.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_18 PF12847.2 EGO55874.1 - 1.6e-10 41.5 0.0 3e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO55874.1 - 1.5e-08 34.5 0.0 3.3e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO55874.1 - 6.8e-08 32.2 0.5 1.5e-07 31.1 0.3 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO55874.1 - 8.2e-06 26.2 0.0 3.7e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO55874.1 - 0.00022 21.6 2.3 0.0006 20.2 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EGO55874.1 - 0.00028 20.4 0.0 0.00059 19.4 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EGO55874.1 - 0.0028 17.0 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 EGO55874.1 - 0.0032 17.4 0.0 0.0047 16.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGO55874.1 - 0.01 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.15 EGO55874.1 - 0.012 14.6 0.0 0.083 11.9 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EGO55874.1 - 0.022 15.0 0.1 0.056 13.8 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EGO55874.1 - 0.029 13.5 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 EGO55874.1 - 0.03 13.4 0.0 0.26 10.3 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EGO55874.1 - 0.038 13.6 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF1840 PF08895.6 EGO55874.1 - 0.046 13.7 0.3 0.079 12.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) MTS PF05175.9 EGO55874.1 - 0.092 12.1 0.0 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_24 PF13578.1 EGO55874.1 - 0.12 13.1 0.0 0.3 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF3328 PF11807.3 EGO55875.1 - 0.00012 21.8 2.5 0.007 16.0 0.5 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) OPT PF03169.10 EGO55876.1 - 6.9e-170 566.5 43.2 8.6e-170 566.2 29.9 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_S41 PF03572.13 EGO55876.1 - 2.3e-09 36.8 0.0 5.7e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase family S41 DUF3328 PF11807.3 EGO55877.1 - 1.3e-32 113.2 0.3 1.6e-32 112.9 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans_2 PF11951.3 EGO55878.1 - 1.3e-39 135.8 5.8 1.9e-39 135.3 4.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO55878.1 - 4e-07 29.8 6.1 7.9e-07 28.8 4.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KNTase_C PF07827.6 EGO55879.1 - 5.5e-05 22.9 1.5 35 4.1 0.0 5.3 1 1 5 7 7 7 0 KNTase C-terminal domain VIT PF08487.5 EGO55879.1 - 0.00015 21.4 0.8 29 4.4 0.0 4.9 1 1 1 5 5 5 0 Vault protein inter-alpha-trypsin domain DUF1104 PF06518.6 EGO55879.1 - 0.0011 19.0 13.5 19 5.4 0.1 7.0 1 1 8 10 10 10 0 Protein of unknown function (DUF1104) Musclin PF11037.3 EGO55879.1 - 0.11 12.1 0.7 9.8 5.8 0.0 3.5 1 1 3 4 4 4 0 Insulin-resistance promoting peptide in skeletal muscle DapH_N PF08503.5 EGO55879.1 - 0.11 12.6 18.4 14 5.8 0.1 6.5 1 1 3 7 7 7 0 Tetrahydrodipicolinate succinyltransferase N-terminal VirB8 PF04335.8 EGO55879.1 - 0.14 11.7 5.2 0.43 10.1 0.1 3.9 1 1 1 5 5 5 0 VirB8 protein HS1_rep PF02218.10 EGO55879.1 - 0.33 10.8 16.1 32 4.5 0.1 6.3 4 4 2 6 6 6 0 Repeat in HS1/Cortactin YfdX PF10938.3 EGO55879.1 - 0.83 9.2 10.2 18 4.9 0.9 4.4 1 1 3 4 4 4 0 YfdX protein APP_amyloid PF10515.4 EGO55879.1 - 1 9.6 10.1 14 5.9 0.1 5.4 5 1 1 6 6 6 0 beta-amyloid precursor protein C-terminus DUF3244 PF11589.3 EGO55879.1 - 1.6 8.4 9.9 20 4.9 0.8 3.9 1 1 1 3 3 3 0 Domain of unknown function (DUF3244) DUF4629 PF15442.1 EGO55881.1 - 7 6.7 13.7 0.13 12.3 2.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4629) peroxidase PF00141.18 EGO55882.1 - 9e-84 280.5 0.0 1.2e-43 149.2 0.0 2.3 2 0 0 2 2 2 2 Peroxidase Cwf_Cwc_15 PF04889.7 EGO55883.1 - 0.63 9.7 2.4 0.85 9.2 1.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1996 PF09362.5 EGO55885.1 - 3e-86 288.8 0.2 4.8e-86 288.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Abhydrolase_6 PF12697.2 EGO55886.1 - 1.1e-08 35.2 0.0 3.4e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO55886.1 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO55886.1 - 0.023 14.2 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Aa_trans PF01490.13 EGO55888.1 - 3.2e-77 259.7 27.2 4e-77 259.4 18.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.1 EGO55888.1 - 7.9 6.1 7.3 1.2 8.7 0.3 3.1 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase AA_permease_2 PF13520.1 EGO55890.1 - 1.1e-46 159.2 53.4 1.4e-46 158.9 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO55890.1 - 6.6e-24 84.0 51.5 9e-24 83.6 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease UCH PF00443.24 EGO55891.1 - 5.7e-45 153.5 0.0 8.2e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGO55891.1 - 2.5e-24 85.1 12.7 2.1e-19 69.4 1.3 3.2 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EGO55891.1 - 2.8e-20 72.9 0.0 2.4e-16 60.0 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EGO55891.1 - 1.9e-16 59.3 0.2 4.9e-07 29.3 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain NifU_N PF01592.11 EGO55892.1 - 2.1e-53 179.5 0.0 2.8e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain Striatin PF08232.7 EGO55893.1 - 0.0011 19.2 6.8 0.0011 19.2 4.7 2.9 3 0 0 3 3 3 2 Striatin family CDC45 PF02724.9 EGO55893.1 - 0.059 11.4 32.8 0.37 8.7 10.5 2.2 2 0 0 2 2 2 0 CDC45-like protein GST_N PF02798.15 EGO55894.1 - 4.3e-13 49.2 0.0 7.9e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGO55894.1 - 7.6e-11 42.0 0.0 1.5e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO55894.1 - 5.8e-10 39.0 0.0 1.8e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO55894.1 - 6.5e-10 38.8 0.1 1.3e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO55894.1 - 5.3e-08 32.6 0.0 1.1e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO55894.1 - 9.8e-05 22.7 0.0 0.00015 22.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HORMA PF02301.13 EGO55895.1 - 2.3e-44 151.3 0.0 2.9e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 HORMA domain DUF2411 PF10304.4 EGO55895.1 - 0.077 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) DEAD PF00270.24 EGO55896.1 - 1.3e-47 161.4 0.0 7.1e-45 152.5 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO55896.1 - 6e-29 99.7 0.1 1.6e-28 98.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MIP-T3 PF10243.4 EGO55896.1 - 0.00012 20.7 36.6 0.00015 20.4 25.4 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF1253 PF06862.7 EGO55896.1 - 0.00014 20.4 0.0 0.00014 20.4 0.0 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF1253) CMS1 PF14617.1 EGO55896.1 - 0.37 9.8 0.0 0.37 9.8 0.0 3.4 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Rft-1 PF04506.8 EGO55897.1 - 2e-79 267.4 0.5 1.8e-76 257.6 0.3 2.5 1 1 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.1 EGO55897.1 - 0.039 13.4 26.0 0.16 11.3 0.1 4.1 4 0 0 4 4 4 0 Polysaccharide biosynthesis protein Tmpp129 PF10272.4 EGO55897.1 - 0.24 10.0 0.4 0.65 8.6 0.0 1.8 2 0 0 2 2 2 0 Putative transmembrane protein precursor TFIIA PF03153.8 EGO55898.1 - 0.58 10.0 5.1 0.66 9.8 3.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CBM_10 PF02013.11 EGO55899.1 - 0.0097 16.1 2.3 2.2 8.5 0.1 2.3 2 0 0 2 2 2 2 Cellulose or protein binding domain TRP PF06011.7 EGO55900.1 - 5.6e-143 476.6 29.6 6.8e-143 476.3 20.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGO55900.1 - 1.1e-41 142.1 0.0 1.9e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 ML-like domain Glyco_hydro_16 PF00722.16 EGO55905.1 - 1.5e-16 60.2 0.0 5.8e-16 58.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EGO55905.1 - 4.9e-05 21.6 0.6 0.083 11.0 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) PHY PF00360.15 EGO55906.1 - 5.1e-24 84.4 0.0 8.4e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 Phytochrome region GAF PF01590.21 EGO55906.1 - 4.4e-19 69.1 0.0 9.3e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 GAF domain HATPase_c PF02518.21 EGO55906.1 - 1.9e-17 63.0 0.1 3.5e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGO55906.1 - 1.3e-12 47.6 0.0 2.8e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EGO55906.1 - 2.2e-07 30.7 0.0 1.3e-06 28.3 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 EGO55906.1 - 0.00027 21.0 0.0 0.0033 17.5 0.0 2.4 2 0 0 2 2 2 1 GAF domain PAS_2 PF08446.6 EGO55906.1 - 0.00033 21.0 0.0 0.0012 19.2 0.0 2.0 1 0 0 1 1 1 1 PAS fold GAF_2 PF13185.1 EGO55906.1 - 0.063 13.7 0.0 1.2 9.6 0.0 3.0 2 1 0 2 2 2 0 GAF domain HATPase_c_2 PF13581.1 EGO55906.1 - 0.088 12.5 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 EGO55906.1 - 0.25 10.9 0.0 0.43 10.2 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LisH PF08513.6 EGO55907.1 - 0.1 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 LisH TRADD_N PF09034.5 EGO55911.1 - 0.037 14.0 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 TRADD, N-terminal domain TRAPP PF04051.11 EGO55912.1 - 2.6e-36 124.4 0.1 3.2e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.27 EGO55913.1 - 5.6e-53 175.0 5.8 1.2e-09 37.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGO55913.1 - 0.12 10.5 0.5 0.98 7.4 0.3 2.2 1 1 0 1 1 1 0 Nucleoporin Nup120/160 IncA PF04156.9 EGO55914.1 - 0.11 12.0 1.3 0.18 11.3 0.9 1.3 1 0 0 1 1 1 0 IncA protein MSP1_C PF07462.6 EGO55914.1 - 0.45 8.8 1.7 0.64 8.3 1.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SP_C-Propep PF08999.5 EGO55915.1 - 0.0029 17.0 3.2 0.0038 16.6 2.2 1.2 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide EphA2_TM PF14575.1 EGO55915.1 - 0.013 15.8 0.1 0.016 15.5 0.1 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.6 EGO55915.1 - 0.14 11.5 3.1 0.22 10.9 2.2 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF3176 PF11374.3 EGO55916.1 - 8.3e-41 138.3 1.1 5.5e-40 135.6 0.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) GPI2 PF06432.6 EGO55916.1 - 0.1 11.9 6.2 0.17 11.2 2.9 2.2 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase MARVEL PF01284.18 EGO55916.1 - 5.8 6.7 10.0 0.9 9.3 0.0 2.8 3 0 0 3 3 3 0 Membrane-associating domain HA2 PF04408.18 EGO55917.1 - 3.1e-16 59.2 2.1 4.6e-16 58.6 0.0 2.4 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGO55917.1 - 3.5e-12 45.9 0.1 7.9e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO55917.1 - 1.3e-09 37.7 0.0 3.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EGO55917.1 - 3.9e-08 33.1 0.0 9.8e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EGO55917.1 - 2.9e-07 30.6 0.7 1.6e-06 28.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EGO55917.1 - 0.0038 16.7 0.0 0.008 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EGO55917.1 - 0.0099 16.2 3.4 0.44 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EGO55917.1 - 0.015 15.5 0.2 0.054 13.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter KaiC PF06745.8 EGO55917.1 - 0.062 12.4 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 KaiC DUF3554 PF12074.3 EGO55918.1 - 1.8e-99 333.4 6.4 2.3e-99 333.0 0.0 4.4 5 1 0 5 5 5 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 EGO55918.1 - 4e-45 152.0 64.2 7.1e-10 39.0 0.1 18.8 11 3 8 19 19 19 9 HEAT repeats HEAT PF02985.17 EGO55918.1 - 1.5e-35 118.0 42.5 0.0067 16.4 0.0 23.9 27 0 0 27 27 25 7 HEAT repeat HEAT_EZ PF13513.1 EGO55918.1 - 7.9e-34 115.2 77.9 2.7e-06 27.6 0.0 24.9 22 3 8 30 30 27 7 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGO55918.1 - 9.6e-17 61.1 0.8 0.43 10.9 0.0 9.4 8 1 0 8 8 8 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EGO55918.1 - 1.7e-16 60.2 0.0 0.00038 19.8 0.0 6.7 5 2 2 7 7 7 5 CLASP N terminal Cnd1 PF12717.2 EGO55918.1 - 1.7e-13 50.7 0.7 0.69 9.7 0.0 10.0 6 2 3 10 10 10 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EGO55918.1 - 4.7e-13 49.4 3.0 0.00024 21.0 0.0 6.3 5 2 1 6 6 6 3 Parkin co-regulated protein Adaptin_N PF01602.15 EGO55918.1 - 1.4e-11 43.4 7.8 0.053 11.8 0.1 8.2 4 3 4 8 8 8 4 Adaptin N terminal region UME PF08064.8 EGO55918.1 - 4.6e-07 29.7 2.2 11 6.0 0.0 8.1 6 2 3 9 9 9 0 UME (NUC010) domain Ipi1_N PF12333.3 EGO55918.1 - 1.3e-05 25.1 0.3 0.14 12.1 0.0 6.6 7 0 0 7 7 7 1 Rix1 complex component involved in 60S ribosome maturation DUF2454 PF10521.4 EGO55918.1 - 0.016 14.2 0.6 0.23 10.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2454) FANCI_S2 PF14676.1 EGO55918.1 - 0.021 14.7 0.5 11 5.9 0.0 4.7 5 0 0 5 5 5 0 FANCI solenoid 2 TFCD_C PF12612.3 EGO55918.1 - 0.066 12.6 3.2 0.31 10.4 0.5 3.6 3 1 0 3 3 3 0 Tubulin folding cofactor D C terminal DUF1846 PF08903.6 EGO55918.1 - 0.12 10.7 0.4 0.23 9.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) MMS19_C PF12460.3 EGO55918.1 - 0.91 8.1 16.6 0.33 9.6 0.2 5.8 5 1 0 5 5 5 0 RNAPII transcription regulator C-terminal Ribosomal_L19e PF01280.15 EGO55919.1 - 1.2e-60 203.5 8.3 1.2e-60 203.5 5.7 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 EGO55919.1 - 0.064 12.4 1.0 0.06 12.5 0.7 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SHMT PF00464.14 EGO55920.1 - 1.4e-194 646.0 0.0 1.8e-194 645.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase 2OG-FeII_Oxy_2 PF13532.1 EGO55921.1 - 2.3e-26 92.8 0.0 4.6e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 EGO55921.1 - 2.3e-22 79.7 0.3 1.1e-21 77.5 0.0 2.2 2 1 0 2 2 2 1 Isochorismatase family GST_C_2 PF13410.1 EGO55921.1 - 0.013 15.4 0.0 0.046 13.6 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO55921.1 - 0.019 15.4 0.2 0.087 13.3 0.2 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BBS2_C PF14782.1 EGO55921.1 - 1.5 7.2 2.6 2.5 6.5 1.8 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal LRR_4 PF12799.2 EGO55922.1 - 4.6e-23 80.3 5.2 2.8e-07 30.0 0.5 4.8 2 2 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO55922.1 - 1.1e-20 73.1 5.7 1.2e-08 34.5 0.4 4.4 3 1 2 5 5 5 3 Leucine rich repeat Pkinase_Tyr PF07714.12 EGO55922.1 - 8.5e-16 57.7 0.0 2.3e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase LRR_1 PF00560.28 EGO55922.1 - 1.3e-14 51.9 6.2 0.091 12.8 0.0 7.0 7 0 0 7 7 6 4 Leucine Rich Repeat Pkinase PF00069.20 EGO55922.1 - 4.8e-13 48.8 0.0 5.9e-12 45.2 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain LRR_7 PF13504.1 EGO55922.1 - 2.4e-07 29.8 7.8 2.4 8.7 0.1 6.8 7 0 0 7 7 7 2 Leucine rich repeat Kdo PF06293.9 EGO55922.1 - 7.6e-05 21.8 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.1 EGO55922.1 - 0.0043 16.9 8.5 21 5.5 0.1 5.5 5 0 0 5 5 5 0 Leucine Rich repeat GvpK PF05121.7 EGO55922.1 - 0.042 13.6 0.7 0.12 12.1 0.5 1.7 1 0 0 1 1 1 0 Gas vesicle protein K LRR_5 PF13306.1 EGO55922.1 - 0.13 12.0 0.0 0.56 9.9 0.0 1.9 2 1 1 3 3 3 0 Leucine rich repeats (6 copies) Cmyb_C PF09316.5 EGO55922.1 - 0.2 11.3 0.1 0.31 10.6 0.1 1.2 1 0 0 1 1 1 0 C-myb, C-terminal Bromo_TP PF07524.8 EGO55923.1 - 2e-22 78.6 0.0 3.5e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 EGO55923.1 - 2.7e-12 46.5 4.6 1.1e-05 25.3 1.4 2.9 2 0 0 2 2 2 2 Transcription factor TFIID complex subunit 8 C-term Med21 PF11221.3 EGO55923.1 - 0.4 10.6 7.1 3.5 7.5 1.0 2.4 2 0 0 2 2 2 0 Subunit 21 of Mediator complex AvrE PF11725.3 EGO55923.1 - 3 4.7 10.6 3.9 4.3 7.4 1.1 1 0 0 1 1 1 0 Pathogenicity factor WD40 PF00400.27 EGO55924.1 - 9.4e-61 199.6 24.0 4.5e-11 42.1 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGO55924.1 - 0.00044 18.5 4.6 0.16 10.0 0.1 3.7 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EGO55924.1 - 0.02 13.2 0.0 3.3 5.9 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain TMEM154 PF15102.1 EGO55925.1 - 0.00018 21.2 0.1 0.00026 20.7 0.1 1.2 1 0 0 1 1 1 1 TMEM154 protein family AJAP1_PANP_C PF15298.1 EGO55925.1 - 0.00027 20.8 1.3 0.00036 20.4 0.9 1.1 1 0 0 1 1 1 1 AJAP1/PANP C-terminus DUF4381 PF14316.1 EGO55925.1 - 0.015 15.3 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PRCC PF10253.4 EGO55925.1 - 0.029 15.0 0.1 0.041 14.5 0.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SIT PF15330.1 EGO55925.1 - 0.032 14.3 0.5 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Rifin_STEVOR PF02009.11 EGO55925.1 - 0.061 12.9 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family Endonuc_Holl PF10107.4 EGO55925.1 - 0.072 12.7 0.0 0.092 12.4 0.0 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF2611 PF11022.3 EGO55925.1 - 0.11 12.5 0.0 1.9 8.6 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2611) WBP-1 PF11669.3 EGO55925.1 - 0.12 12.4 0.3 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF3413 PF11893.3 EGO55925.1 - 0.66 8.8 3.9 1 8.2 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3413) Mucin PF01456.12 EGO55925.1 - 1.1 8.9 11.5 36 4.1 8.4 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3112 PF11309.3 EGO55926.1 - 2.9e-05 23.8 5.9 2.9e-05 23.8 4.1 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3112) Ribosomal_L22 PF00237.14 EGO55927.1 - 4.1e-18 65.2 1.3 2.5e-09 37.0 0.2 2.6 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e CFEM PF05730.6 EGO55928.1 - 3.1e-11 42.9 11.1 5e-11 42.2 7.7 1.3 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.5 EGO55928.1 - 0.013 14.8 1.7 0.027 13.7 1.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SLR1-BP PF07333.7 EGO55928.1 - 0.45 10.7 6.3 0.15 12.3 1.6 1.9 2 0 0 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) YWFCY PF14293.1 EGO55929.1 - 0.032 14.0 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 YWFCY protein MAGE_N PF12440.3 EGO55930.1 - 0.69 10.2 3.2 0.3 11.3 0.1 2.0 3 0 0 3 3 3 0 Melanoma associated antigen family N terminal Hydrolase_6 PF13344.1 EGO55931.1 - 1.3e-22 79.5 0.0 2.6e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO55931.1 - 3.1e-09 36.4 0.0 5.6e-08 32.3 0.0 2.7 2 1 0 2 2 2 1 HAD-hyrolase-like DUF1237 PF06824.6 EGO55932.1 - 2.6e-172 573.1 0.0 3.1e-172 572.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Shisa PF13908.1 EGO55933.1 - 0.0023 18.1 0.0 0.0023 18.1 0.0 3.2 3 0 0 3 3 3 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 EGO55933.1 - 0.089 13.1 0.2 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Abhydrolase_6 PF12697.2 EGO55934.1 - 8.5e-14 51.9 0.1 2.6e-13 50.4 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EGO55934.1 - 1.3e-13 50.2 0.0 8.7e-12 44.3 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 EGO55934.1 - 8.8e-13 48.2 0.0 1.6e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGO55934.1 - 0.0001 21.8 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EGO55934.1 - 0.00034 19.9 0.0 0.0008 18.6 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EGO55934.1 - 0.0038 16.6 0.2 0.01 15.2 0.1 1.7 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 EGO55934.1 - 0.0082 15.5 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) TPR_12 PF13424.1 EGO55934.1 - 0.14 12.0 0.3 0.33 10.9 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Methyltransf_23 PF13489.1 EGO55935.1 - 7.7e-05 22.4 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO55935.1 - 0.0019 18.6 0.0 0.012 16.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO55935.1 - 0.0027 17.7 0.0 0.0054 16.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO55935.1 - 0.006 16.9 0.1 0.013 15.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Serglycin PF04360.7 EGO55935.1 - 0.01 15.5 0.5 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 Serglycin Zip PF02535.17 EGO55936.1 - 8.1 5.3 10.9 12 4.7 7.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter HET PF06985.6 EGO55937.1 - 5.8e-18 65.3 0.0 1.4e-17 64.1 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAM163 PF15069.1 EGO55939.1 - 0.053 14.0 0.5 0.12 12.9 0.4 1.6 1 0 0 1 1 1 0 FAM163 family Adeno_E3_CR2 PF02439.10 EGO55940.1 - 0.011 15.2 0.2 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Shisa PF13908.1 EGO55940.1 - 0.044 13.9 0.0 0.044 13.9 0.0 3.4 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Plasmodium_Vir PF05795.6 EGO55940.1 - 0.11 11.6 1.9 0.5 9.5 1.3 2.0 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Syndecan PF01034.15 EGO55940.1 - 0.27 10.9 0.4 0.53 9.9 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain Amidohydro_4 PF13147.1 EGO55943.1 - 4.3e-14 53.2 2.2 2.8e-12 47.2 0.5 3.7 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EGO55943.1 - 2.3e-06 27.4 0.1 0.00013 21.7 0.0 2.5 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGO55943.1 - 3.8e-06 26.6 1.1 8.1e-06 25.5 0.1 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EGO55943.1 - 0.00014 21.2 0.1 0.00095 18.4 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family AA_permease PF00324.16 EGO55945.1 - 6.3e-139 463.3 37.0 7.7e-139 463.0 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO55945.1 - 2.2e-38 131.9 37.3 2.9e-38 131.5 25.8 1.1 1 0 0 1 1 1 1 Amino acid permease ALMT PF11744.3 EGO55945.1 - 0.36 9.4 2.3 0.57 8.7 1.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Methyltransf_23 PF13489.1 EGO55946.1 - 1e-13 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO55946.1 - 1.2e-10 41.6 0.0 2.4e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO55946.1 - 1.2e-07 32.0 0.0 7.2e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO55946.1 - 1.4e-07 31.2 0.0 1.7e-05 24.4 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO55946.1 - 4.3e-07 30.4 0.0 4.5e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO55946.1 - 5.5e-05 22.3 0.0 0.0015 17.7 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EGO55946.1 - 0.00035 20.6 0.1 0.0011 18.9 0.0 1.8 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EGO55946.1 - 0.0097 16.2 0.0 0.029 14.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO55946.1 - 0.033 13.2 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EGO55946.1 - 0.081 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 EGO55947.1 - 3.4e-18 65.8 0.0 4.9e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO55947.1 - 1.7e-10 41.2 0.0 3.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO55947.1 - 5.6e-09 36.3 0.0 2.8e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO55947.1 - 7.8e-09 36.0 0.0 8.7e-08 32.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO55947.1 - 1.4e-07 31.2 0.0 2.2e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO55947.1 - 0.00053 19.1 0.0 0.0073 15.4 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EGO55947.1 - 0.003 16.6 0.0 0.0077 15.2 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.4 EGO55947.1 - 0.009 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EGO55947.1 - 0.011 16.1 0.0 0.027 14.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EGO55947.1 - 0.022 14.7 0.1 0.054 13.4 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 EGO55947.1 - 0.032 13.6 0.0 0.076 12.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 EGO55947.1 - 0.076 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Herpes_BLLF1 PF05109.8 EGO55947.1 - 4.2 5.2 8.7 5.5 4.8 6.0 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Mo-co_dimer PF03404.11 EGO55948.1 - 5e-10 39.1 0.0 8.5e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.19 EGO55948.1 - 5.6e-07 29.6 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Ank PF00023.25 EGO55950.1 - 6.7e-17 60.3 0.8 7.4e-08 31.8 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EGO55950.1 - 2.7e-16 59.2 1.4 1.6e-08 34.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO55950.1 - 4.5e-16 58.9 0.2 9.8e-16 57.8 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGO55950.1 - 6e-12 44.5 0.2 1.5e-05 24.7 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGO55950.1 - 1.3e-11 44.6 0.2 3.4e-11 43.3 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) SAC3_GANP PF03399.11 EGO55950.1 - 0.03 13.8 0.1 0.064 12.8 0.1 1.4 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family CorA PF01544.13 EGO55950.1 - 0.66 8.9 5.2 0.066 12.2 0.4 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DNAPolymera_Pol PF11590.3 EGO55950.1 - 0.93 9.2 3.5 3.2 7.4 0.1 2.6 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol DUF2566 PF10753.4 EGO55951.1 - 0.041 13.8 3.1 1.9 8.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2566) DUF3302 PF11742.3 EGO55951.1 - 0.093 12.5 0.1 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3302) Glyco_hydro_47 PF01532.15 EGO55952.1 - 1.1e-163 545.0 0.0 1.4e-163 544.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CDC45 PF02724.9 EGO55954.1 - 3.2 5.6 15.5 4.3 5.2 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1162 PF06650.7 EGO55955.1 - 2.5e-90 302.4 0.0 3.9e-88 295.2 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EGO55955.1 - 8.1e-44 147.9 0.1 2.4e-43 146.4 0.1 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EGO55955.1 - 2.4e-06 27.5 0.0 1.6e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 ATG C terminal domain DUF3429 PF11911.3 EGO55956.1 - 1.1e-40 138.9 7.0 1.4e-40 138.5 4.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF4220 PF13968.1 EGO55956.1 - 0.0082 15.2 1.5 0.012 14.6 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4220) Ycf1 PF05758.7 EGO55956.1 - 0.016 12.9 10.0 0.023 12.4 6.9 1.2 1 0 0 1 1 1 0 Ycf1 DUF4407 PF14362.1 EGO55956.1 - 0.047 12.6 3.7 0.15 10.9 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) IncA PF04156.9 EGO55956.1 - 0.052 13.1 0.8 0.11 12.1 0.6 1.5 1 0 0 1 1 1 0 IncA protein Zip PF02535.17 EGO55956.1 - 0.28 10.1 0.5 0.44 9.4 0.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter HET PF06985.6 EGO55958.1 - 9.1e-23 80.9 0.0 2.3e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_23 PF13489.1 EGO55959.1 - 3.6e-20 72.3 0.0 5.1e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO55959.1 - 7.5e-10 39.1 0.0 1.7e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO55959.1 - 9.7e-07 29.3 0.0 6.6e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO55959.1 - 1e-06 29.0 0.0 6.6e-06 26.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO55959.1 - 1.7e-05 24.4 0.0 0.00024 20.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO55959.1 - 0.00051 19.1 0.0 0.00099 18.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EGO55959.1 - 0.0011 18.1 0.0 0.01 14.9 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGO55959.1 - 0.0012 19.2 0.0 0.0041 17.4 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGO55959.1 - 0.002 17.5 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_PK PF05891.7 EGO55959.1 - 0.022 14.0 0.1 0.064 12.5 0.1 1.7 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase FtsJ PF01728.14 EGO55959.1 - 0.022 14.7 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.9 EGO55959.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 EGO55959.1 - 0.054 12.6 0.0 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 EGO55960.1 - 4.1e-16 59.1 0.0 5.9e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO55960.1 - 9.1e-09 35.7 0.0 1.8e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO55960.1 - 2.9e-07 31.0 0.0 2.9e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO55960.1 - 4.3e-05 23.1 0.0 0.00054 19.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO55960.1 - 8.3e-05 22.9 0.0 0.00049 20.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGO55960.1 - 0.0032 16.9 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 EGO55960.1 - 0.0036 16.3 0.0 0.0079 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EGO55960.1 - 0.0044 16.1 0.0 0.056 12.5 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGO55960.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.10 EGO55960.1 - 0.089 12.4 0.0 8.4 5.9 0.0 2.9 3 0 0 3 3 3 0 Hypothetical methyltransferase Methyltransf_25 PF13649.1 EGO55960.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EGO55960.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase Ammonium_transp PF00909.16 EGO55961.1 - 1.7e-103 346.1 15.4 2e-103 345.9 10.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1479 PF07350.7 EGO55964.1 - 1.9e-165 550.4 0.0 2.4e-165 550.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) p450 PF00067.17 EGO55965.1 - 1.8e-42 145.4 0.0 2.2e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 STAT_bind PF02864.10 EGO55965.1 - 0.038 13.5 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 STAT protein, DNA binding domain p450 PF00067.17 EGO55966.1 - 1.2e-50 172.3 0.0 2e-49 168.4 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.9 EGO55967.1 - 4e-29 101.9 0.7 6.7e-29 101.2 0.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO55967.1 - 5.2e-14 52.4 1.0 1.9e-11 44.1 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EGO55967.1 - 4.3e-13 48.6 0.0 1.3e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EGO55967.1 - 1.9e-07 31.3 0.0 0.0024 17.9 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EGO55967.1 - 1.3e-06 28.6 0.1 4.4e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Reductase C-terminal NAD_binding_9 PF13454.1 EGO55967.1 - 0.00072 19.3 1.5 0.28 10.9 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EGO55967.1 - 0.0033 16.4 0.0 0.11 11.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.6 EGO55967.1 - 0.094 11.8 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) AMP-binding PF00501.23 EGO55968.1 - 1.7e-73 247.3 0.0 2.1e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO55968.1 - 1.4e-13 51.5 0.6 7.1e-13 49.3 0.4 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Hydrolase PF00702.21 EGO55968.1 - 0.0011 19.4 0.7 0.034 14.5 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Polysacc_lyase PF14099.1 EGO55969.1 - 2.3e-44 151.7 6.1 2.7e-44 151.5 4.2 1.0 1 0 0 1 1 1 1 Polysaccharide lyase N-glycanase_C PF09113.5 EGO55969.1 - 9.7e-05 22.0 0.8 0.00017 21.3 0.1 1.6 2 0 0 2 2 2 1 Peptide-N-glycosidase F, C terminal Laminin_G_2 PF02210.19 EGO55969.1 - 0.075 13.0 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain Sugar_tr PF00083.19 EGO55970.1 - 2.4e-75 253.8 27.6 2.8e-75 253.6 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO55970.1 - 4.4e-27 94.7 26.6 9.4e-25 87.0 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGO55970.1 - 5.1e-07 28.2 2.2 8.2e-07 27.5 1.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EGO55970.1 - 1.3e-06 27.1 1.6 1.3e-06 27.1 1.1 3.4 2 2 1 3 3 3 1 MFS/sugar transport protein Methyltransf_2 PF00891.13 EGO55973.1 - 4.5e-27 94.7 0.0 1e-26 93.6 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase MarR_2 PF12802.2 EGO55973.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 EGO55973.1 - 0.042 14.1 0.0 0.089 13.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_AraC PF00165.18 EGO55973.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Ank_2 PF12796.2 EGO55974.1 - 8.9e-53 176.5 2.1 3.3e-13 49.7 0.0 8.1 5 3 2 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGO55974.1 - 3.2e-42 138.2 8.7 0.00033 20.6 0.0 13.6 13 1 0 13 13 13 9 Ankyrin repeat Ank PF00023.25 EGO55974.1 - 2.5e-39 131.1 7.5 7.5e-05 22.3 0.2 13.6 14 0 0 14 14 14 8 Ankyrin repeat Ank_4 PF13637.1 EGO55974.1 - 4.2e-38 129.0 13.8 2.9e-05 24.4 0.0 12.3 8 4 5 13 13 13 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO55974.1 - 5.6e-35 118.5 4.2 7.5e-07 29.2 0.1 10.3 9 1 1 10 10 10 7 Ankyrin repeats (many copies) F-box-like PF12937.2 EGO55974.1 - 0.028 14.1 0.1 0.028 14.1 0.1 2.4 3 0 0 3 3 3 0 F-box-like DUF2802 PF10975.3 EGO55974.1 - 0.15 11.8 0.0 0.53 10.0 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) HET PF06985.6 EGO55975.1 - 3.3e-29 101.8 0.2 2.3e-28 99.0 0.0 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) S-antigen PF05756.6 EGO55975.1 - 0.041 13.8 1.6 0.08 12.9 1.1 1.4 1 0 0 1 1 1 0 S-antigen protein Usp PF00582.21 EGO55975.1 - 0.062 13.4 0.2 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Universal stress protein family An_peroxidase PF03098.10 EGO55976.1 - 3.6e-98 329.2 0.0 1.2e-95 320.9 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EGO55976.1 - 3.2e-05 22.6 0.0 0.0037 15.8 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF2235 PF09994.4 EGO55977.1 - 7.9e-99 330.4 0.8 1.4e-98 329.6 0.5 1.4 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Macoilin PF09726.4 EGO55977.1 - 0.01 14.1 7.3 0.016 13.5 5.1 1.3 1 0 0 1 1 1 0 Transmembrane protein CDC45 PF02724.9 EGO55977.1 - 0.28 9.1 3.0 0.48 8.3 2.1 1.4 1 0 0 1 1 1 0 CDC45-like protein UPF0449 PF15136.1 EGO55978.1 - 0.081 13.1 0.3 10 6.3 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Sec5 PF15469.1 EGO55978.1 - 0.11 12.2 0.5 0.17 11.6 0.4 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 WXG100 PF06013.7 EGO55978.1 - 0.14 12.1 1.8 0.34 10.9 1.3 1.7 1 0 0 1 1 1 0 Proteins of 100 residues with WXG AAA_12 PF13087.1 EGO55979.1 - 1.9e-35 122.1 0.0 3.3e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGO55979.1 - 1.8e-22 80.0 0.6 6.5e-22 78.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGO55979.1 - 9.9e-08 31.6 0.0 5.3e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 EGO55979.1 - 4.6e-06 25.8 0.3 0.0063 15.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EGO55979.1 - 0.0042 16.6 0.0 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGO55979.1 - 0.013 14.9 0.0 0.037 13.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein UvrD-helicase PF00580.16 EGO55979.1 - 0.031 13.5 0.1 0.091 12.0 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 EGO55979.1 - 0.072 13.0 0.1 0.072 13.0 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain UvrD_C_2 PF13538.1 EGO55979.1 - 0.12 12.4 0.0 0.5 10.5 0.0 2.1 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain MFS_1 PF07690.11 EGO55980.1 - 1.3e-27 96.4 39.5 1.3e-26 93.1 24.8 3.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO55980.1 - 8.1e-13 47.4 5.4 2e-09 36.1 1.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) AAA PF00004.24 EGO55981.1 - 6.6e-10 39.2 0.0 1.6e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.7 EGO55981.1 - 0.0033 16.9 0.2 0.061 12.7 0.0 2.4 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.1 EGO55981.1 - 0.13 12.2 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EGO55981.1 - 0.18 11.9 0.2 1.9 8.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain K-box PF01486.12 EGO55982.1 - 0.99 9.2 5.0 13 5.6 0.2 2.7 2 1 1 3 3 3 0 K-box region Terminase_6 PF03237.10 EGO55983.1 - 0.013 14.2 0.7 0.021 13.6 0.5 1.2 1 0 0 1 1 1 0 Terminase-like family DUF2794 PF10984.3 EGO55985.1 - 0.11 12.3 1.0 1.6 8.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2794) Myb_DNA-bind_5 PF13873.1 EGO55986.1 - 0.063 13.1 0.4 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4229 PF14012.1 EGO55988.1 - 0.14 12.0 7.5 0.45 10.4 4.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) PrgI PF12666.2 EGO55988.1 - 0.31 11.2 2.3 0.74 9.9 0.7 2.1 2 1 0 2 2 2 0 PrgI family protein Glucosaminidase PF01832.15 EGO55989.1 - 0.14 12.2 0.1 0.32 11.1 0.0 1.5 1 1 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase OTT_1508_deam PF14441.1 EGO55991.1 - 6.8e-30 103.7 0.1 1.8e-29 102.3 0.1 1.7 2 0 0 2 2 2 1 OTT_1508-like deaminase FliD_N PF02465.13 EGO55992.1 - 3 8.2 8.6 1.2 9.5 4.1 1.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Alpha-amylase PF00128.19 EGO55993.1 - 9.2e-23 81.1 0.0 5.1e-22 78.6 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EGO55993.1 - 0.0039 15.0 0.0 0.91 7.2 0.0 2.9 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 VIT1 PF01988.14 EGO55994.1 - 3.8e-64 216.0 3.9 4.6e-64 215.7 2.7 1.1 1 0 0 1 1 1 1 VIT family DUF1700 PF08006.6 EGO55994.1 - 0.046 13.0 3.4 0.56 9.4 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) PqqD PF05402.7 EGO55994.1 - 0.12 12.3 0.1 0.32 11.0 0.1 1.7 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) p450 PF00067.17 EGO55995.1 - 4.1e-59 200.3 0.1 7.7e-46 156.5 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 Stirrup PF09061.1 EGO55995.1 - 0.091 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Stirrup BRO1 PF03097.13 EGO55998.1 - 1.8e-114 382.4 0.0 3.3e-114 381.5 0.0 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EGO55998.1 - 3.1e-75 252.9 4.9 3.1e-75 252.9 3.4 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Fringe PF02434.11 EGO55999.1 - 6.6e-08 32.0 0.0 1.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.7 EGO55999.1 - 0.00029 20.1 0.0 0.00064 19.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF604 DUF500 PF04366.7 EGO56001.1 - 1.8e-54 182.4 0.0 2.9e-54 181.8 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Cellulase PF00150.13 EGO56002.1 - 8.4e-21 74.3 2.9 2.1e-20 73.0 2.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Mpv17_PMP22 PF04117.7 EGO56002.1 - 0.015 14.8 0.2 0.88 9.2 0.1 2.9 3 0 0 3 3 3 0 Mpv17 / PMP22 family Bac_luciferase PF00296.15 EGO56003.1 - 3.3e-60 203.7 0.0 4.5e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 EGO56004.1 - 4.3e-30 104.6 31.6 5.7e-30 104.2 21.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_T4_gp19 PF06841.7 EGO56004.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 T4-like virus tail tube protein gp19 Pyr_redox_3 PF13738.1 EGO56007.1 - 2.6e-20 73.3 0.1 1e-19 71.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGO56007.1 - 6.9e-14 50.9 0.1 4.2e-12 45.0 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EGO56007.1 - 6.4e-09 35.7 0.0 2e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EGO56007.1 - 2.2e-08 33.4 0.2 3.4e-06 26.2 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGO56007.1 - 2.2e-06 27.7 0.0 5.9e-05 23.0 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO56007.1 - 6.3e-05 22.8 0.1 0.23 11.2 0.0 3.7 3 1 1 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 EGO56007.1 - 0.0034 16.3 0.1 1.3 7.8 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Mqo PF06039.10 EGO56007.1 - 0.027 12.6 0.1 0.84 7.7 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.17 EGO56007.1 - 0.3 9.8 0.0 12 4.5 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.11 EGO56008.1 - 3.5e-10 39.1 25.5 3.5e-10 39.1 17.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily ADH_N PF08240.7 EGO56009.1 - 0.00033 20.3 0.0 0.00075 19.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MepB PF08877.5 EGO56009.1 - 0.21 11.1 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 MepB protein Bac_luciferase PF00296.15 EGO56010.1 - 5.1e-56 190.0 2.6 6.8e-56 189.6 1.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase eIF3_N PF09440.5 EGO56011.1 - 1.2e-52 177.5 5.0 1.2e-52 177.5 3.5 2.0 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EGO56011.1 - 6.5e-16 58.5 0.2 6.5e-16 58.5 0.2 2.1 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EGO56011.1 - 0.00067 19.4 0.1 0.0018 18.0 0.1 1.8 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 RPN7 PF10602.4 EGO56011.1 - 0.026 13.8 0.2 0.066 12.5 0.1 1.6 1 1 0 1 1 1 0 26S proteasome subunit RPN7 Img2 PF05046.9 EGO56012.1 - 2.2e-24 85.5 0.0 3.1e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 EGO56012.1 - 0.014 15.1 0.5 0.032 14.0 0.4 1.5 1 1 0 1 1 1 0 Translation initiation factor SUI1 PRCC PF10253.4 EGO56012.1 - 0.028 15.1 0.4 0.031 14.9 0.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Dicty_REP PF05086.7 EGO56012.1 - 0.27 8.9 0.8 0.27 8.9 0.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ARID PF01388.16 EGO56013.1 - 4e-18 65.0 0.0 8.9e-18 63.9 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain EVE PF01878.13 EGO56014.1 - 2.3e-46 157.3 0.0 3.9e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 EVE domain Mucin PF01456.12 EGO56014.1 - 3 7.6 11.6 4.9 6.9 8.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein U3_assoc_6 PF08640.6 EGO56015.1 - 7.7e-25 86.4 0.1 2.9e-24 84.6 0.1 2.0 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EGO56015.1 - 0.016 15.8 2.3 2.4 9.0 0.0 4.2 3 1 2 5 5 5 0 Tetratricopeptide repeat NRDE-2 PF08424.5 EGO56015.1 - 0.023 13.5 0.0 0.17 10.7 0.0 2.2 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference Frag1 PF10277.4 EGO56016.1 - 2.6e-41 141.4 11.1 2.6e-41 141.4 7.7 3.0 3 1 0 3 3 3 2 Frag1/DRAM/Sfk1 family MFS_1 PF07690.11 EGO56017.1 - 2.4e-21 75.8 23.5 2.4e-21 75.8 16.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF373 PF04123.8 EGO56017.1 - 0.052 12.5 3.0 0.072 12.0 1.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Sugar_tr PF00083.19 EGO56017.1 - 0.43 9.0 26.7 0.16 10.4 13.8 2.6 1 1 1 2 2 2 0 Sugar (and other) transporter DUF3938 PF13074.1 EGO56017.1 - 1.5 8.6 6.0 0.5 10.2 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) Band_7 PF01145.20 EGO56018.1 - 1e-12 48.3 0.0 1e-12 48.3 0.0 3.4 2 2 1 3 3 3 1 SPFH domain / Band 7 family Apc1 PF12859.2 EGO56020.1 - 6.9e-28 96.9 0.1 1.7e-27 95.6 0.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EGO56020.1 - 9.2e-11 41.3 2.7 0.0003 20.8 0.0 4.7 5 0 0 5 5 5 2 Proteasome/cyclosome repeat Clathrin PF00637.15 EGO56021.1 - 5.7e-20 71.3 0.4 1.2e-18 67.0 0.1 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 EGO56021.1 - 2.1e-06 27.3 2.3 0.081 12.8 1.0 4.2 3 1 0 3 3 3 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 EGO56021.1 - 0.003 17.3 0.4 0.0069 16.2 0.3 1.6 1 0 0 1 1 1 1 Ring finger domain Vps39_1 PF10366.4 EGO56021.1 - 0.0045 16.9 0.2 0.017 15.1 0.0 2.0 2 0 0 2 2 1 1 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.1 EGO56021.1 - 0.023 14.4 0.1 0.048 13.3 0.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain TPR_7 PF13176.1 EGO56021.1 - 0.062 13.1 0.5 0.58 10.1 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Nic96 PF04097.9 EGO56021.1 - 0.082 11.0 0.3 5.4 5.0 0.1 2.1 2 0 0 2 2 2 0 Nup93/Nic96 RXT2_N PF08595.6 EGO56021.1 - 0.17 11.7 9.6 0.48 10.2 6.6 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal Daxx PF03344.10 EGO56021.1 - 0.4 9.0 12.8 0.89 7.9 8.8 1.5 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EGO56021.1 - 0.57 8.0 14.7 0.95 7.2 10.2 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 EGO56021.1 - 2.7 7.5 15.2 2.4 7.7 8.9 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region NOA36 PF06524.7 EGO56021.1 - 3 7.0 11.4 5.6 6.1 7.9 1.3 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.6 EGO56021.1 - 3.3 5.7 7.4 8.9 4.2 3.6 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 PPP4R2 PF09184.6 EGO56021.1 - 4.6 6.7 12.9 9.5 5.6 8.9 1.4 1 0 0 1 1 1 0 PPP4R2 Pectate_lyase_3 PF12708.2 EGO56022.1 - 1.2e-73 247.9 15.0 2.5e-57 194.6 7.5 2.9 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EGO56022.1 - 1.6e-05 24.2 2.3 0.015 14.7 0.4 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DNase_NucA_NucB PF14040.1 EGO56022.1 - 0.00049 20.2 1.3 0.0086 16.2 0.9 2.4 1 1 0 1 1 1 1 Deoxyribonuclease NucA/NucB LysM PF01476.15 EGO56023.1 - 0.0005 19.9 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 LysM domain SET PF00856.23 EGO56025.1 - 1.5e-13 51.4 0.3 3.2e-12 47.0 0.2 2.3 1 1 0 1 1 1 1 SET domain SAF PF08666.7 EGO56025.1 - 0.012 15.9 0.1 6.2 7.2 0.0 2.4 2 0 0 2 2 2 0 SAF domain Glyco_trans_2_3 PF13632.1 EGO56026.1 - 0.029 14.0 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family group 2 DOCK-C2 PF14429.1 EGO56027.1 - 2e-22 79.7 0.0 3.5e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EGO56027.1 - 5.3e-09 35.6 0.1 1.6e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 EGO56027.1 - 9.1e-06 24.9 0.0 2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGO56027.1 - 0.0013 18.2 0.0 0.0061 16.1 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain DUF2256 PF10013.4 EGO56028.1 - 0.32 10.7 3.2 0.59 9.9 2.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Esterase_phd PF10503.4 EGO56030.1 - 1.5e-22 79.9 1.3 2.1e-22 79.4 0.9 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EGO56030.1 - 2.1e-13 49.9 0.4 3.7e-13 49.2 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO56030.1 - 2e-06 27.6 0.2 2.8e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO56030.1 - 6.3e-05 22.9 0.6 9.1e-05 22.4 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGO56030.1 - 0.00029 20.4 0.1 0.00046 19.8 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EGO56030.1 - 0.0003 20.4 0.1 0.00039 20.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EGO56030.1 - 0.0013 18.2 0.4 0.0046 16.4 0.1 1.8 2 0 0 2 2 2 1 Putative esterase COesterase PF00135.23 EGO56030.1 - 0.0017 17.1 0.1 0.0024 16.6 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.11 EGO56030.1 - 0.016 14.6 0.1 2.1 7.7 0.1 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Tannase PF07519.6 EGO56030.1 - 0.019 13.6 0.5 0.029 13.0 0.3 1.4 1 0 0 1 1 1 0 Tannase and feruloyl esterase AXE1 PF05448.7 EGO56030.1 - 0.02 13.4 0.1 0.12 10.8 0.1 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 EGO56030.1 - 0.14 11.7 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ank_5 PF13857.1 EGO56031.1 - 1.6e-09 37.6 0.1 5.1e-06 26.5 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EGO56031.1 - 1.1e-08 34.4 0.0 0.00015 21.4 0.0 3.9 4 1 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EGO56031.1 - 1.7e-08 34.6 0.0 4e-07 30.2 0.0 3.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGO56031.1 - 1.1e-06 28.2 0.1 0.00092 19.2 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 EGO56031.1 - 2.1e-06 28.0 0.0 0.091 13.3 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) DNA_binding_1 PF01035.15 EGO56033.1 - 2.6e-22 78.3 0.1 3.5e-22 77.9 0.1 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain His_Phos_1 PF00300.17 EGO56034.1 - 3.2e-22 79.2 0.1 5.1e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EGO56034.1 - 0.0016 17.8 0.2 0.0036 16.7 0.1 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SDA1 PF05285.7 EGO56035.1 - 1e-87 294.5 39.5 9.4e-87 291.2 21.5 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EGO56035.1 - 6.4e-19 67.9 0.1 1.7e-18 66.6 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain Alpha-amylase PF00128.19 EGO56037.1 - 3.5e-23 82.5 0.0 1.3e-22 80.6 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EGO56037.1 - 1.7e-05 22.8 0.0 0.27 8.9 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.5 EGO56037.1 - 0.025 14.4 2.8 0.04 13.8 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) HSP70 PF00012.15 EGO56038.1 - 2.2e-62 210.8 14.8 2.2e-56 191.0 0.0 3.1 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 EGO56038.1 - 0.00045 18.9 0.1 0.0018 16.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Syntaxin-6_N PF09177.6 EGO56038.1 - 0.03 14.7 2.5 1.4 9.3 0.3 3.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Asp PF00026.18 EGO56039.1 - 6.8e-39 133.9 0.0 3.8e-32 111.7 0.0 2.4 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO56039.1 - 0.0022 17.9 0.0 0.023 14.6 0.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal DUF4140 PF13600.1 EGO56040.1 - 0.00055 20.3 1.9 0.00084 19.7 1.3 1.4 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) BBP1_C PF15272.1 EGO56040.1 - 0.00092 18.8 2.8 0.00092 18.8 1.9 1.4 2 0 0 2 2 2 1 Spindle pole body component BBP1, C-terminal Fez1 PF06818.10 EGO56040.1 - 0.0011 19.0 1.8 0.0017 18.4 1.3 1.2 1 0 0 1 1 1 1 Fez1 Filament PF00038.16 EGO56040.1 - 0.028 13.9 2.3 0.033 13.6 1.6 1.1 1 0 0 1 1 1 0 Intermediate filament protein DivIC PF04977.10 EGO56040.1 - 0.042 13.3 2.4 0.49 9.9 0.7 2.3 2 0 0 2 2 2 0 Septum formation initiator TBPIP PF07106.8 EGO56040.1 - 0.051 13.1 1.3 0.074 12.6 0.9 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 EGO56040.1 - 0.052 11.3 1.7 0.059 11.2 1.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Golgin_A5 PF09787.4 EGO56040.1 - 0.069 11.6 4.6 0.072 11.5 3.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF241 PF03087.9 EGO56040.1 - 0.07 12.6 1.1 0.11 11.9 0.8 1.4 1 0 0 1 1 1 0 Arabidopsis protein of unknown function EMP24_GP25L PF01105.19 EGO56040.1 - 0.098 12.3 0.3 0.098 12.3 0.2 1.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4164 PF13747.1 EGO56040.1 - 0.11 12.6 4.2 0.21 11.7 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) SlyX PF04102.7 EGO56040.1 - 0.39 11.1 5.1 2.9 8.3 0.4 2.8 1 1 1 3 3 3 0 SlyX Bap31 PF05529.7 EGO56040.1 - 0.44 9.9 2.5 0.67 9.3 1.7 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like BLOC1_2 PF10046.4 EGO56040.1 - 0.58 10.3 4.3 11 6.2 0.6 2.3 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 EGO56040.1 - 0.71 10.1 3.7 3.4 7.9 2.6 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 EGO56040.1 - 0.73 8.7 3.7 0.8 8.5 2.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CRT10 PF08728.5 EGO56040.1 - 1 7.2 3.7 1.2 7.0 2.6 1.0 1 0 0 1 1 1 0 CRT10 Bromodomain PF00439.20 EGO56041.1 - 1.4e-13 50.5 0.0 5.7e-13 48.5 0.0 2.0 2 0 0 2 2 2 1 Bromodomain Turandot PF07240.6 EGO56041.1 - 0.094 12.2 0.1 0.23 10.9 0.1 1.6 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Filament PF00038.16 EGO56042.1 - 0.0061 16.0 28.4 0.013 15.0 19.7 1.4 1 0 0 1 1 1 1 Intermediate filament protein TSC22 PF01166.13 EGO56042.1 - 6.9 6.7 12.5 8.1 6.4 0.2 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family Cyt-b5 PF00173.23 EGO56043.1 - 3.1e-10 39.7 0.0 6.2e-10 38.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GIIM PF08388.6 EGO56043.1 - 0.0031 17.2 0.1 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 Group II intron, maturase-specific domain Cupredoxin_1 PF13473.1 EGO56044.1 - 0.025 14.4 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Cupredoxin-like domain Copper-bind PF00127.15 EGO56044.1 - 0.048 13.8 0.4 0.11 12.7 0.3 1.5 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family SSP160 PF06933.6 EGO56044.1 - 1.4 6.7 29.4 0.12 10.2 16.5 1.8 1 1 1 2 2 2 0 Special lobe-specific silk protein SSP160 CENP-X PF09415.5 EGO56045.1 - 9.7e-29 99.0 0.0 2.1e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 CENP-S associating Centromere protein X DUF789 PF05623.7 EGO56045.1 - 0.8 9.1 8.8 0.52 9.7 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF789) Rhabdo_ncap PF00945.13 EGO56045.1 - 0.88 8.0 4.5 1.3 7.5 3.1 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein TEBP_beta PF07404.6 EGO56045.1 - 1.5 7.9 3.5 1.8 7.5 1.1 1.8 2 0 0 2 2 2 0 Telomere-binding protein beta subunit (TEBP beta) RR_TM4-6 PF06459.7 EGO56045.1 - 7.5 6.3 10.2 10 5.9 7.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mito_carr PF00153.22 EGO56046.1 - 1.4e-67 223.4 3.4 1.8e-23 82.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S25 PF03297.10 EGO56047.1 - 7.8e-40 135.1 5.8 8.5e-40 135.0 4.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein RNA_pol_Rpc34 PF05158.7 EGO56047.1 - 0.0016 17.7 0.2 0.0027 16.9 0.1 1.3 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_24 PF13412.1 EGO56047.1 - 0.0033 16.7 0.1 0.0051 16.1 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 EGO56047.1 - 0.0043 16.7 0.1 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_DeoR PF08220.7 EGO56047.1 - 0.0043 16.5 0.1 0.0057 16.1 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.15 EGO56047.1 - 0.019 15.0 0.0 0.028 14.5 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.14 EGO56047.1 - 0.023 14.3 0.2 0.031 13.9 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 EGO56047.1 - 0.077 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 HTH domain HTH_IclR PF09339.5 EGO56047.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain FeoC PF09012.5 EGO56047.1 - 0.13 11.9 0.4 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator Ribosomal_S7 PF00177.16 EGO56048.1 - 3.9e-41 140.0 0.8 4.7e-41 139.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Acetyltransf_1 PF00583.19 EGO56049.1 - 3.7e-07 30.0 0.8 8.9e-07 28.8 0.3 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 EGO56049.1 - 2.3e-06 28.0 0.0 0.0089 16.5 0.0 2.8 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGO56049.1 - 7.8e-05 22.7 0.0 0.00021 21.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGO56049.1 - 8.8e-05 22.3 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 EGO56049.1 - 0.0049 16.9 0.0 0.0092 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGO56049.1 - 0.049 13.4 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO56049.1 - 0.06 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.20 EGO56050.1 - 1.6e-28 99.7 0.0 1e-27 97.1 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO56050.1 - 1.2e-17 64.5 0.0 1.5e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO56050.1 - 3.2e-09 36.7 0.0 7.7e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO56050.1 - 8.9e-05 22.0 0.0 0.00029 20.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO56050.1 - 0.0016 18.4 0.1 0.011 15.7 0.0 2.2 2 1 1 3 3 3 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EGO56050.1 - 0.0046 16.7 0.2 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EGO56050.1 - 0.0059 15.5 0.0 0.013 14.4 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.14 EGO56050.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Baculo_PEP_C PF04513.7 EGO56051.1 - 1.9 8.3 18.9 0.025 14.3 1.4 4.5 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4175 PF13779.1 EGO56051.1 - 5.3 4.5 32.5 8.6 3.9 22.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DNA_pol_B_palm PF14792.1 EGO56052.1 - 0.098 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase beta palm Tubulin PF00091.20 EGO56055.1 - 2.8e-69 233.2 0.0 3.9e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGO56055.1 - 4.9e-49 165.5 0.1 8.2e-49 164.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EGO56055.1 - 0.0011 18.5 0.0 0.0026 17.2 0.0 1.6 2 0 0 2 2 2 1 Tubulin domain Lipase_3 PF01764.20 EGO56055.1 - 0.087 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) MAD PF05557.8 EGO56056.1 - 0.00023 19.4 15.7 0.00038 18.7 10.9 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein AAA_13 PF13166.1 EGO56056.1 - 0.00054 18.5 15.4 0.00054 18.5 10.7 1.5 2 0 0 2 2 2 1 AAA domain Myosin_tail_1 PF01576.14 EGO56056.1 - 0.001 16.9 21.0 0.0016 16.3 14.5 1.2 1 0 0 1 1 1 1 Myosin tail Cob_adeno_trans PF01923.13 EGO56056.1 - 0.033 13.9 7.0 0.064 13.0 3.9 2.0 1 1 0 1 1 1 0 Cobalamin adenosyltransferase V_ATPase_I PF01496.14 EGO56056.1 - 0.034 12.0 12.7 0.04 11.7 6.5 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EGO56056.1 - 0.055 13.0 23.3 0.19 11.3 16.1 1.9 1 1 0 1 1 1 0 IncA protein BLOC1_2 PF10046.4 EGO56056.1 - 0.062 13.4 15.6 0.17 12.0 3.1 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF310 PF03750.8 EGO56056.1 - 0.072 13.2 7.1 0.2 11.8 2.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF310) Reo_sigmaC PF04582.7 EGO56056.1 - 0.077 12.1 2.8 0.046 12.9 0.6 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF2450 PF10475.4 EGO56056.1 - 0.24 10.2 9.8 0.27 10.0 5.2 1.9 1 1 1 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) FliT PF05400.8 EGO56056.1 - 0.29 11.5 0.1 0.29 11.5 0.1 3.7 3 1 0 4 4 2 0 Flagellar protein FliT Spc7 PF08317.6 EGO56056.1 - 0.42 9.2 22.1 1.9 7.0 15.4 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.1 EGO56056.1 - 0.82 8.8 22.7 0.85 8.7 5.5 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.4 EGO56056.1 - 0.95 7.6 13.3 1.6 6.8 9.2 1.4 1 0 0 1 1 1 0 Transmembrane protein CENP-F_leu_zip PF10473.4 EGO56056.1 - 1.5 8.7 26.4 2.2 8.1 16.1 2.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ALMT PF11744.3 EGO56056.1 - 1.6 7.2 8.7 0.75 8.3 4.6 1.5 2 0 0 2 2 2 0 Aluminium activated malate transporter OEP PF02321.13 EGO56056.1 - 2 7.9 7.4 1.7 8.1 3.8 1.7 1 1 1 2 2 2 0 Outer membrane efflux protein TPR_MLP1_2 PF07926.7 EGO56056.1 - 2.6 7.8 21.7 1.6e+02 1.9 15.1 2.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 EGO56056.1 - 2.9 7.7 12.2 1.3 8.8 3.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EGO56056.1 - 4.7 7.5 9.5 56 4.0 4.1 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4200 PF13863.1 EGO56056.1 - 9 6.2 27.3 18 5.3 5.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) BTB_2 PF02214.17 EGO56058.1 - 6.2e-05 23.1 0.1 0.069 13.3 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain TyeA PF09059.5 EGO56058.1 - 0.07 13.0 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 TyeA zf-CSL PF05207.8 EGO56059.1 - 9.6e-25 85.8 0.4 1.2e-24 85.6 0.3 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EGO56059.1 - 0.0034 17.3 0.3 0.0056 16.6 0.2 1.4 1 0 0 1 1 1 1 Zinc ribbon domain Prok-RING_1 PF14446.1 EGO56059.1 - 0.29 10.8 1.7 0.77 9.5 1.2 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 tRNA-synt_1 PF00133.17 EGO56061.1 - 1.1e-39 135.9 0.1 3.2e-29 101.4 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EGO56061.1 - 2.8e-19 69.0 0.1 3.4e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EGO56061.1 - 5.4e-13 48.9 0.6 1.2e-12 47.8 0.2 1.8 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EGO56061.1 - 4.6e-09 35.8 0.0 1.1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Clat_adaptor_s PF01217.15 EGO56063.1 - 6.3e-43 145.8 0.0 1.1e-42 145.0 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.11 EGO56064.1 - 9e-36 121.9 0.0 1.2e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Sds3 PF08598.6 EGO56064.1 - 0.045 13.2 0.0 0.09 12.2 0.0 1.5 2 0 0 2 2 2 0 Sds3-like DUF2962 PF11176.3 EGO56064.1 - 0.13 11.8 0.2 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2962) Tetraspannin PF00335.15 EGO56065.1 - 7e-05 22.2 1.1 0.00018 20.8 0.0 1.9 2 0 0 2 2 2 1 Tetraspanin family DEAD PF00270.24 EGO56066.1 - 4e-34 117.5 0.0 6.6e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO56066.1 - 4e-22 77.8 0.0 7.7e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO56066.1 - 0.0009 19.1 0.0 0.0009 19.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EGO56066.1 - 0.089 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain CDC45 PF02724.9 EGO56066.1 - 4.3 5.2 18.2 6.2 4.7 12.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PIGA PF08288.7 EGO56067.1 - 5.2e-47 158.1 1.5 5.2e-47 158.1 1.0 2.6 3 0 0 3 3 3 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EGO56067.1 - 9.2e-29 100.0 0.0 1.4e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EGO56067.1 - 3.8e-18 65.8 0.7 8e-18 64.7 0.5 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EGO56067.1 - 3.1e-16 59.9 0.0 5.5e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EGO56067.1 - 9.4e-16 58.1 0.0 1.6e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EGO56067.1 - 5e-06 26.3 0.2 8.3e-06 25.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EGO56067.1 - 2.6e-05 24.4 0.0 8.4e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 RasGEF PF00617.14 EGO56068.1 - 2.1e-51 174.3 0.0 4.3e-51 173.3 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGO56068.1 - 3.7e-18 65.5 0.0 1.1e-17 63.9 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 EGO56068.1 - 5.1e-05 22.7 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO56068.1 - 0.00041 19.6 0.0 0.00077 18.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SLEI_Leptospira PF07620.6 EGO56068.1 - 0.27 11.1 2.0 0.67 9.8 0.3 2.4 2 0 0 2 2 2 0 SLEI Exo_endo_phos PF03372.18 EGO56069.1 - 5.5e-06 26.5 0.3 7.7e-06 26.0 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.12 EGO56069.1 - 4.6e-05 23.3 0.4 0.00031 20.6 0.3 2.0 2 0 0 2 2 2 1 Jacalin-like lectin domain Ank_2 PF12796.2 EGO56070.1 - 6e-37 125.8 0.2 2.9e-17 62.7 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGO56070.1 - 5.4e-30 101.6 1.7 0.00011 21.8 0.0 7.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.1 EGO56070.1 - 2.9e-25 85.7 1.2 0.0015 18.6 0.0 7.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EGO56070.1 - 2.4e-19 69.3 0.6 3.2e-05 24.2 0.0 6.3 2 1 4 6 6 6 6 Ankyrin repeats (many copies) NACHT PF05729.7 EGO56070.1 - 1.9e-11 43.9 0.1 4.9e-11 42.5 0.1 1.7 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.1 EGO56070.1 - 3.5e-11 42.9 0.3 0.59 10.4 0.0 6.6 2 2 5 7 7 7 4 Ankyrin repeats (many copies) AAA_16 PF13191.1 EGO56070.1 - 7.2e-10 39.1 0.0 3.2e-09 37.0 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO56070.1 - 2.2e-07 31.0 0.1 1e-06 28.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EGO56070.1 - 0.0058 15.6 0.0 0.95 8.3 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EGO56070.1 - 0.029 14.5 0.0 0.081 13.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EGO56070.1 - 0.17 11.6 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EGO56070.1 - 0.44 9.9 3.4 1.4 8.3 0.1 3.0 3 1 0 3 3 3 0 AAA-like domain SNF2_N PF00176.18 EGO56071.1 - 1.9e-65 220.6 0.2 2.8e-65 220.0 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO56071.1 - 1.8e-11 43.7 0.3 4.9e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO56071.1 - 1.2e-09 37.9 0.1 1.9e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EGO56071.1 - 4.4e-05 23.3 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NACHT PF05729.7 EGO56071.1 - 0.025 14.2 0.4 2.4 7.7 0.1 2.9 3 0 0 3 3 3 0 NACHT domain DEAD_2 PF06733.10 EGO56071.1 - 0.031 13.6 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 DEAD_2 zf-C3HC4 PF00097.20 EGO56071.1 - 0.035 13.7 0.4 0.073 12.7 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mid2 PF04478.7 EGO56071.1 - 0.039 13.3 0.1 0.075 12.4 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor AAA_34 PF13872.1 EGO56071.1 - 0.06 12.1 0.0 0.14 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-C3HC4_3 PF13920.1 EGO56071.1 - 0.13 11.9 0.3 0.28 10.8 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CKS PF01111.14 EGO56073.1 - 0.11 12.4 0.2 0.53 10.1 0.0 2.0 1 1 1 2 2 2 0 Cyclin-dependent kinase regulatory subunit Herpes_gE PF02480.11 EGO56074.1 - 0.00049 18.4 0.0 0.00061 18.1 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E RAP1 PF07218.6 EGO56074.1 - 0.069 11.2 0.2 0.1 10.7 0.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Alpha_GJ PF03229.8 EGO56074.1 - 0.073 13.4 7.1 0.034 14.4 2.3 2.2 1 1 1 2 2 2 0 Alphavirus glycoprotein J DUF1517 PF07466.6 EGO56074.1 - 3.7 6.4 8.0 0.72 8.7 2.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1517) Epimerase PF01370.16 EGO56075.1 - 2.5e-17 63.1 0.0 3.3e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EGO56075.1 - 3.3e-08 33.6 0.0 5.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EGO56075.1 - 1.4e-07 30.7 0.0 1.3e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EGO56075.1 - 1.1e-06 27.5 0.0 1.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGO56075.1 - 8.1e-06 24.9 0.0 1.9e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGO56075.1 - 0.00023 21.2 0.0 0.0006 19.8 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EGO56075.1 - 0.00075 19.2 0.0 0.0024 17.5 0.0 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EGO56075.1 - 0.029 13.2 0.0 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sulfotransfer_3 PF13469.1 EGO56076.1 - 0.00047 21.1 0.7 0.00047 21.1 0.5 1.6 2 0 0 2 2 2 1 Sulfotransferase family CBM_1 PF00734.13 EGO56077.1 - 3.9e-13 48.8 7.7 1.3e-12 47.1 5.4 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain zf-RING_5 PF14634.1 EGO56079.1 - 0.0055 16.4 2.6 0.0096 15.6 1.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-CCHC PF00098.18 EGO56079.1 - 1.7 8.7 7.0 1.2 9.2 3.2 2.1 2 0 0 2 2 2 0 Zinc knuckle MFS_1 PF07690.11 EGO56080.1 - 6.6e-29 100.7 51.1 1.3e-23 83.3 23.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO56080.1 - 5.6e-12 44.9 28.5 1.1e-11 44.0 19.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2583 PF10762.4 EGO56080.1 - 0.054 13.6 0.5 0.18 11.9 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) LacAB_rpiB PF02502.13 EGO56080.1 - 0.11 12.1 0.8 0.2 11.2 0.5 1.3 1 0 0 1 1 1 0 Ribose/Galactose Isomerase DUF605 PF04652.11 EGO56081.1 - 3 7.1 11.1 3.2 7.0 7.7 1.1 1 0 0 1 1 1 0 Vta1 like AcetylCoA_hydro PF02550.10 EGO56082.1 - 1.5e-46 158.6 0.0 2.4e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EGO56082.1 - 2e-37 128.2 0.0 3.3e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 EGO56082.1 - 0.11 11.6 0.0 0.53 9.4 0.0 2.1 2 0 0 2 2 2 0 Coenzyme A transferase MFS_1 PF07690.11 EGO56083.1 - 1.8e-16 59.8 28.5 1.8e-16 59.8 19.8 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGO56083.1 - 1.2e-11 44.3 5.4 1.2e-11 44.3 3.8 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 HET PF06985.6 EGO56084.1 - 5e-40 136.8 0.0 1.1e-39 135.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TIR_2 PF13676.1 EGO56084.1 - 0.02 15.0 1.0 0.34 11.0 0.1 2.4 1 1 1 2 2 2 0 TIR domain CK_II_beta PF01214.13 EGO56085.1 - 2.7 7.4 8.0 6.3 6.2 0.1 2.7 1 1 3 4 4 4 0 Casein kinase II regulatory subunit OPT PF03169.10 EGO56086.1 - 1.2e-177 592.1 50.9 1.3e-177 592.0 35.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MtrF PF09472.5 EGO56086.1 - 0.12 11.6 2.7 11 5.2 0.5 2.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF4191 PF13829.1 EGO56086.1 - 4.3 6.3 6.2 2.1 7.4 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) Peptidase_S9 PF00326.16 EGO56087.1 - 1.4e-05 24.4 0.5 3.4e-05 23.1 0.4 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO56087.1 - 0.00022 21.0 0.2 0.00043 20.0 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO56087.1 - 0.009 15.9 0.3 0.013 15.3 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGO56087.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase ArabFuran-catal PF09206.6 EGO56088.1 - 1e-158 527.4 21.6 1.2e-158 527.2 15.0 1.0 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic PS-DH PF14765.1 EGO56088.1 - 0.13 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Polyketide synthase dehydratase EcKinase PF02958.15 EGO56089.1 - 6.2e-14 51.8 0.0 1.4e-12 47.4 0.0 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 EGO56089.1 - 1.1e-06 28.6 0.0 2.3e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EGO56089.1 - 2e-05 23.4 0.0 3.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Fungal_trans_2 PF11951.3 EGO56090.1 - 2.3e-12 46.2 10.8 4.9e-12 45.1 7.5 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO56090.1 - 7.2e-07 29.0 13.2 7.2e-07 29.0 9.2 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bcl-2 PF00452.14 EGO56090.1 - 0.086 12.9 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family HypA PF01155.14 EGO56090.1 - 0.54 9.9 7.0 0.9 9.2 3.4 2.4 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family UPF0075 PF03702.9 EGO56091.1 - 3.1e-83 279.6 0.0 3.6e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) DUF162 PF02589.10 EGO56091.1 - 0.027 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 Sugar_tr PF00083.19 EGO56092.1 - 2.1e-90 303.5 26.1 2.4e-90 303.3 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO56092.1 - 3.4e-27 95.0 42.9 8.1e-16 57.6 12.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_12 PF13087.1 EGO56093.1 - 4.6e-44 150.2 0.1 2.6e-43 147.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGO56093.1 - 1.9e-39 134.8 0.0 8.9e-13 48.5 0.0 5.4 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EGO56093.1 - 3.2e-36 125.0 19.0 5.9e-31 107.8 0.1 6.1 5 1 0 5 5 5 2 AAA domain AAA_19 PF13245.1 EGO56093.1 - 3e-23 81.3 2.2 3e-10 39.7 0.0 5.0 4 0 0 4 4 4 4 Part of AAA domain AAA_30 PF13604.1 EGO56093.1 - 8e-16 58.2 2.8 2.5e-05 23.9 0.0 6.4 5 0 0 5 5 5 3 AAA domain AAA_22 PF13401.1 EGO56093.1 - 1.6e-15 57.4 2.8 0.058 13.5 0.1 7.5 4 3 0 4 4 4 4 AAA domain AAA_5 PF07728.9 EGO56093.1 - 1.1e-12 47.8 0.2 0.17 11.6 0.0 5.0 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EGO56093.1 - 1.8e-12 48.1 13.9 0.065 14.0 0.0 6.2 6 0 0 6 6 4 4 AAA domain Mg_chelatase PF01078.16 EGO56093.1 - 4.9e-09 35.6 0.1 0.032 13.3 0.0 5.0 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EGO56093.1 - 3.2e-08 33.3 4.0 0.74 9.1 0.0 6.4 5 1 1 6 6 6 1 AAA-like domain AAA_33 PF13671.1 EGO56093.1 - 3.4e-08 33.4 1.9 0.58 10.0 0.1 5.7 4 0 0 4 4 4 2 AAA domain AAA_14 PF13173.1 EGO56093.1 - 4.5e-08 33.0 0.0 0.025 14.5 0.0 4.4 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.17 EGO56093.1 - 1.3e-07 31.7 0.5 0.66 10.1 0.0 4.7 4 0 0 4 4 4 2 RNA helicase IstB_IS21 PF01695.12 EGO56093.1 - 2.1e-07 30.5 0.0 0.97 8.8 0.0 4.6 4 0 0 4 4 4 3 IstB-like ATP binding protein Torsin PF06309.6 EGO56093.1 - 5.8e-07 29.4 0.1 3.3 7.6 0.0 4.8 4 1 0 4 4 4 1 Torsin AAA_16 PF13191.1 EGO56093.1 - 8.7e-07 29.0 17.4 0.18 11.8 0.0 6.4 7 0 0 7 7 6 3 AAA ATPase domain AAA_24 PF13479.1 EGO56093.1 - 3.9e-05 23.3 8.1 0.22 11.0 0.2 5.1 5 0 0 5 5 5 1 AAA domain KaiC PF06745.8 EGO56093.1 - 7e-05 22.0 1.8 0.098 11.7 0.0 4.6 4 0 0 4 4 4 1 KaiC AAA_25 PF13481.1 EGO56093.1 - 0.00024 20.5 3.4 0.29 10.4 0.0 5.1 4 0 0 4 4 4 1 AAA domain ResIII PF04851.10 EGO56093.1 - 0.00049 19.9 4.7 0.016 15.0 0.0 4.4 5 0 0 5 5 3 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EGO56093.1 - 0.0014 18.9 25.2 1.3 9.3 0.0 6.9 7 1 0 7 7 5 4 AAA domain SRP54 PF00448.17 EGO56093.1 - 0.0036 16.7 2.1 0.54 9.6 0.0 4.1 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain AAA_28 PF13521.1 EGO56093.1 - 0.0052 16.7 9.5 3.2 7.6 0.1 5.4 5 0 0 5 5 4 1 AAA domain MobB PF03205.9 EGO56093.1 - 0.011 15.4 1.2 33 4.1 0.0 4.5 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EGO56093.1 - 0.014 14.8 0.0 0.065 12.7 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain UvrD_C_2 PF13538.1 EGO56093.1 - 0.025 14.7 0.0 0.19 11.8 0.0 2.7 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain NTPase_1 PF03266.10 EGO56093.1 - 0.11 12.2 4.4 27 4.4 0.0 4.3 4 0 0 4 4 4 0 NTPase Utp21 PF04192.7 EGO56094.1 - 0.06 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain HET PF06985.6 EGO56095.1 - 6.2e-24 84.7 0.0 1.3e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PAT1 PF09770.4 EGO56096.1 - 0.012 13.8 23.8 0.015 13.5 16.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF533 PF04391.7 EGO56096.1 - 3.2 7.0 7.6 2.2 7.6 4.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF533) adh_short PF00106.20 EGO56098.1 - 1.4e-20 73.8 0.0 2.1e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase HET PF06985.6 EGO56098.1 - 2.5e-18 66.5 0.4 2.5e-17 63.3 0.0 2.3 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.1 EGO56098.1 - 8.2e-09 35.5 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO56098.1 - 1.1e-06 28.4 0.0 2.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EGO56098.1 - 0.024 14.4 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KH_1 PF00013.24 EGO56100.1 - 5.7e-44 147.5 15.1 3.3e-15 55.4 1.5 3.8 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 EGO56100.1 - 4.4e-31 105.9 16.9 1.9e-11 43.3 1.2 4.1 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 EGO56100.1 - 1.7e-12 46.6 3.3 0.0095 15.4 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EGO56100.1 - 8.5e-09 34.9 4.3 0.1 12.2 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EGO56100.1 - 0.0011 18.7 1.6 0.98 9.2 0.0 3.2 3 0 0 3 3 3 2 NusA-like KH domain SLS PF14611.1 EGO56100.1 - 0.025 13.9 0.0 3 7.2 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial inner-membrane-bound regulator Asp PF00026.18 EGO56101.1 - 1.3e-40 139.5 0.0 2e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EGO56101.1 - 2.3e-06 27.9 0.0 1.2 9.7 0.0 3.7 3 0 0 3 3 3 3 Aspartyl protease TAXi_C PF14541.1 EGO56101.1 - 0.0004 19.9 0.1 0.0014 18.1 0.0 2.1 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EGO56101.1 - 0.015 15.1 0.0 0.42 10.4 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DEAD PF00270.24 EGO56102.1 - 1e-43 148.7 0.1 3.8e-43 146.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EGO56102.1 - 2.7e-22 78.0 0.1 6.8e-22 76.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EGO56102.1 - 3e-21 75.0 0.0 3.7e-20 71.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1754 PF08555.5 EGO56102.1 - 6.3 7.4 22.6 19 5.9 15.6 1.8 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) 6PF2K PF01591.13 EGO56103.1 - 4e-79 264.8 0.1 5e-79 264.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGO56103.1 - 1.8e-32 112.6 0.0 3.4e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EGO56103.1 - 5.6e-08 32.7 0.0 1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGO56103.1 - 0.00032 19.9 0.0 0.00049 19.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EGO56103.1 - 0.0025 18.6 0.1 0.031 15.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain Methyltransf_26 PF13659.1 EGO56103.1 - 0.08 12.9 0.1 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain APS_kinase PF01583.15 EGO56103.1 - 0.1 12.2 0.0 0.39 10.3 0.0 2.0 1 1 0 1 1 1 0 Adenylylsulphate kinase NMT1 PF09084.6 EGO56105.1 - 1.2e-76 257.1 0.0 1.4e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EGO56105.1 - 1.2e-10 41.2 0.8 0.0038 16.6 0.1 3.9 2 1 2 4 4 4 3 NMT1-like family Phosphonate-bd PF12974.2 EGO56105.1 - 0.02 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF829 PF05705.9 EGO56107.1 - 6.1e-34 117.7 0.0 1.3e-33 116.6 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF3176 PF11374.3 EGO56108.1 - 5.4e-24 84.2 3.4 1.5e-23 82.7 2.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) zf-NPL4 PF05020.10 EGO56108.1 - 0.051 13.2 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 NPL4 family, putative zinc binding region DUF3176 PF11374.3 EGO56110.1 - 9.8e-16 57.6 1.0 9.8e-16 57.6 0.7 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) PRKCSH PF07915.8 EGO56116.1 - 8.9e-19 68.0 0.3 2.5e-18 66.6 0.2 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EGO56116.1 - 0.033 13.6 0.0 6.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Fungal_trans PF04082.13 EGO56117.1 - 1.9e-11 43.3 0.8 3.3e-11 42.5 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO56117.1 - 3.9e-07 29.8 12.1 6.2e-07 29.2 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.4 EGO56117.1 - 0.091 12.7 4.5 0.15 12.0 3.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Mito_fiss_reg PF05308.6 EGO56118.1 - 2.8 7.2 8.3 3.4 6.9 5.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CFEM PF05730.6 EGO56119.1 - 1.6e-07 31.0 7.3 1.6e-07 31.0 5.0 1.5 2 0 0 2 2 2 1 CFEM domain Cys_rich_CWC PF14375.1 EGO56119.1 - 0.46 10.4 6.0 1.3 9.0 4.2 1.9 1 1 0 1 1 1 0 Cysteine-rich CWC Toxin_3 PF00537.13 EGO56119.1 - 1.2 9.1 7.0 0.077 12.8 0.7 2.0 3 0 0 3 3 3 0 Scorpion toxin-like domain Gamma-thionin PF00304.15 EGO56119.1 - 4.8 7.2 6.5 0.43 10.6 1.0 1.9 2 1 0 2 2 2 0 Gamma-thionin family CFEM PF05730.6 EGO56120.1 - 5.9e-14 51.6 10.7 7e-14 51.4 7.4 1.1 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.15 EGO56120.1 - 0.013 15.4 0.9 0.025 14.5 0.6 1.4 1 0 0 1 1 1 0 Gamma-thionin family ABC_membrane PF00664.18 EGO56121.1 - 3.8e-72 243.0 32.1 3.3e-39 134.9 4.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGO56121.1 - 9.3e-69 230.0 0.0 9.1e-35 119.9 0.0 2.5 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGO56121.1 - 4e-15 55.6 3.3 0.00013 21.2 0.3 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGO56121.1 - 3.9e-13 50.0 0.3 4.3e-05 23.6 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EGO56121.1 - 5.3e-09 36.3 2.9 0.00024 21.1 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EGO56121.1 - 5.9e-09 35.3 0.9 0.0023 17.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EGO56121.1 - 6.6e-08 33.4 0.0 0.018 15.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGO56121.1 - 1.2e-07 31.8 0.2 0.072 13.2 0.0 3.9 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 EGO56121.1 - 5.6e-07 28.5 1.8 0.0011 17.6 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EGO56121.1 - 4e-06 26.1 0.0 0.006 15.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EGO56121.1 - 6.5e-06 25.8 1.4 0.018 14.6 0.0 4.5 4 1 0 4 4 4 1 AAA domain AAA_25 PF13481.1 EGO56121.1 - 1.3e-05 24.7 0.4 0.36 10.1 0.0 3.5 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 EGO56121.1 - 2.6e-05 24.1 0.1 0.2 11.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EGO56121.1 - 0.00014 22.2 0.0 0.55 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EGO56121.1 - 0.00022 21.0 1.5 0.56 10.1 0.3 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 EGO56121.1 - 0.00039 19.5 0.4 0.51 9.4 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin ATP-synt_ab PF00006.20 EGO56121.1 - 0.0006 19.3 0.3 0.78 9.2 0.0 2.8 3 0 0 3 3 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 EGO56121.1 - 0.00064 19.2 5.8 0.2 11.0 0.2 3.5 2 1 1 3 3 3 2 AAA-like domain AAA_18 PF13238.1 EGO56121.1 - 0.00067 19.9 0.1 1.5 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EGO56121.1 - 0.00073 19.7 0.1 3.7 7.7 0.0 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EGO56121.1 - 0.00081 19.2 1.5 0.027 14.3 0.0 2.8 3 0 0 3 3 2 1 Domain of unknown function DUF87 APS_kinase PF01583.15 EGO56121.1 - 0.00083 19.0 0.2 0.75 9.4 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase MMR_HSR1 PF01926.18 EGO56121.1 - 0.0072 16.2 2.5 1.1 9.2 0.1 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase Mg_chelatase PF01078.16 EGO56121.1 - 0.0083 15.2 0.0 2 7.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EGO56121.1 - 0.011 15.6 0.0 7.7 6.4 0.0 3.0 4 0 0 4 4 2 0 AAA domain NB-ARC PF00931.17 EGO56121.1 - 0.012 14.4 0.1 1.9 7.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain MobB PF03205.9 EGO56121.1 - 0.013 15.2 0.3 5 6.8 0.0 2.9 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EGO56121.1 - 0.014 15.0 0.1 8 6.1 0.0 3.5 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EGO56121.1 - 0.021 14.2 0.1 4.4 6.7 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 EGO56121.1 - 0.035 13.5 0.0 0.39 10.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family PRK PF00485.13 EGO56121.1 - 0.054 13.0 0.9 3.3 7.2 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.15 EGO56121.1 - 0.07 11.8 0.0 2.8 6.5 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit RNA_helicase PF00910.17 EGO56121.1 - 0.1 12.8 0.1 5.9 7.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Acetyltransf_7 PF13508.1 EGO56122.1 - 4.8e-08 33.0 0.0 3.4e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO56122.1 - 2.5e-06 27.5 0.0 2.7e-05 24.2 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO56122.1 - 2.7e-06 27.2 0.0 7.9e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGO56122.1 - 0.00063 19.4 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EGO56122.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGO56122.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2686 PF10887.3 EGO56122.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) SAM_PNT PF02198.11 EGO56122.1 - 0.16 11.7 0.1 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain AMP-binding PF00501.23 EGO56123.1 - 1.3e-74 251.1 0.2 3e-73 246.5 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EGO56123.1 - 1.2e-56 191.8 0.0 1.4e-36 125.9 0.0 3.0 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.20 EGO56123.1 - 2.1e-25 88.7 0.0 2.6e-11 43.6 0.0 3.5 3 0 0 3 3 3 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EGO56125.1 - 6.3e-25 88.3 0.0 1.1e-24 87.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO56125.1 - 1.1e-09 38.1 0.0 2.1e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO56125.1 - 0.00019 21.2 0.0 0.0004 20.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family EthD PF07110.6 EGO56125.1 - 0.00022 22.0 0.5 0.15 13.0 0.0 2.8 3 0 0 3 3 3 2 EthD domain Esterase PF00756.15 EGO56125.1 - 0.0037 16.7 0.0 0.009 15.4 0.0 1.7 1 0 0 1 1 1 1 Putative esterase DUF4286 PF14114.1 EGO56125.1 - 0.011 15.9 0.2 1.3 9.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4286) RdRP PF05183.7 EGO56126.1 - 7.4e-162 540.0 0.0 1e-161 539.5 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 EGO56126.1 - 3.9e-05 23.5 0.2 0.00018 21.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO56126.1 - 0.00083 18.9 0.0 0.0029 17.2 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Meth_synt_2 PF01717.13 EGO56127.1 - 5.1e-13 48.6 0.0 4.4e-07 29.1 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EGO56127.1 - 8e-05 22.0 0.1 0.00073 18.8 0.0 2.3 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain DUF3290 PF11694.3 EGO56128.1 - 0.18 11.5 0.2 0.4 10.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF998 PF06197.8 EGO56128.1 - 1.3 8.3 13.5 0.22 10.8 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Bac_Ubq_Cox PF01654.12 EGO56128.1 - 2.1 6.6 9.3 0.32 9.3 1.8 2.1 2 0 0 2 2 2 0 Bacterial Cytochrome Ubiquinol Oxidase DUF1211 PF06736.6 EGO56133.1 - 0.26 11.4 0.0 0.26 11.4 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1211) MerC PF03203.9 EGO56133.1 - 2.3 8.5 8.7 0.38 11.1 1.9 2.4 2 0 0 2 2 2 0 MerC mercury resistance protein MFS_1 PF07690.11 EGO56134.1 - 3.4e-38 131.2 31.3 8e-38 130.0 21.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily V_ATPase_I PF01496.14 EGO56134.1 - 0.0095 13.8 0.1 0.02 12.8 0.0 1.5 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family Rep_fac_C PF08542.6 EGO56135.1 - 8e-19 67.4 0.1 2e-18 66.1 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EGO56135.1 - 2e-16 60.3 0.1 6.8e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EGO56135.1 - 1.1e-14 54.3 0.0 2.5e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 EGO56135.1 - 4.4e-07 30.1 0.1 3.8e-06 27.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.10 EGO56135.1 - 8.3e-07 28.0 0.0 3.7e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EGO56135.1 - 1.5e-06 28.3 0.0 0.00048 20.1 0.0 3.4 1 1 2 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EGO56135.1 - 2.7e-06 26.6 0.1 1.6e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EGO56135.1 - 1.9e-05 24.4 0.1 0.00084 18.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.1 EGO56135.1 - 2.4e-05 24.0 0.0 4.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGO56135.1 - 3.7e-05 23.6 0.0 9.2e-05 22.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain DNA_pol3_delta PF06144.8 EGO56135.1 - 3.9e-05 23.2 0.0 7.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 EGO56135.1 - 6.2e-05 22.6 0.0 0.00018 21.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 EGO56135.1 - 8.8e-05 21.3 0.0 0.2 10.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus DUF815 PF05673.8 EGO56135.1 - 0.00021 20.2 0.0 0.00042 19.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 EGO56135.1 - 0.00035 20.1 0.3 0.0017 17.9 0.1 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGO56135.1 - 0.00065 19.4 0.2 0.004 16.8 0.1 2.4 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 EGO56135.1 - 0.00089 18.5 0.6 0.31 10.2 0.0 2.8 2 1 1 3 3 3 1 PhoH-like protein AAA_24 PF13479.1 EGO56135.1 - 0.0013 18.3 0.0 0.0031 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGO56135.1 - 0.0026 17.2 0.2 0.85 8.9 0.0 2.6 2 1 1 3 3 3 1 AAA-like domain DEAD PF00270.24 EGO56135.1 - 0.0028 17.1 0.3 0.044 13.2 0.0 2.5 2 1 1 3 3 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 EGO56135.1 - 0.0084 15.5 0.0 0.023 14.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EGO56135.1 - 0.0095 15.7 0.0 0.091 12.5 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EGO56135.1 - 0.015 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 EGO56135.1 - 0.017 14.3 0.0 0.1 11.7 0.0 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EGO56135.1 - 0.019 14.3 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.1 EGO56135.1 - 0.022 14.6 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGO56135.1 - 0.031 14.4 0.0 0.065 13.4 0.0 1.7 1 1 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 EGO56135.1 - 0.036 13.5 0.0 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family SNF2_N PF00176.18 EGO56135.1 - 0.06 12.1 0.0 1.9 7.1 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA_17 PF13207.1 EGO56135.1 - 0.078 13.7 0.0 0.15 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGO56135.1 - 0.11 12.8 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain HET PF06985.6 EGO56136.1 - 1.5e-28 99.6 0.1 3.3e-28 98.5 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) OPT PF03169.10 EGO56137.1 - 0.024 13.0 3.1 0.026 12.9 0.9 1.7 2 0 0 2 2 2 0 OPT oligopeptide transporter protein CorA PF01544.13 EGO56137.1 - 0.2 10.6 0.3 0.42 9.5 0.2 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein MFS_1 PF07690.11 EGO56138.1 - 3.8e-32 111.3 47.1 4.4e-22 78.2 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGO56138.1 - 1.2e-07 30.4 18.5 0.0003 19.3 3.4 2.5 1 1 1 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.19 EGO56138.1 - 1.3e-05 23.9 4.8 1.3e-05 23.9 3.3 3.4 2 2 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 EGO56138.1 - 0.00033 20.3 4.5 0.0022 17.7 0.2 3.3 2 1 1 3 3 3 1 MFS_1 like family TRI12 PF06609.8 EGO56138.1 - 0.001 17.3 3.1 0.0024 16.1 2.1 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EGO56138.1 - 0.044 11.8 5.4 3.1 5.7 0.0 3.3 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DUF791 PF05631.9 EGO56138.1 - 1.1 7.8 9.5 0.039 12.6 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF791) MFS_3 PF05977.8 EGO56138.1 - 9.8 4.1 21.0 0.16 10.0 5.9 2.5 2 1 0 2 2 2 0 Transmembrane secretion effector PGPGW PF09656.5 EGO56140.1 - 0.14 11.5 1.9 14 5.0 0.0 3.2 3 0 0 3 3 3 0 Putative transmembrane protein (PGPGW) Bromodomain PF00439.20 EGO56141.1 - 1.1e-35 121.4 0.1 3.9e-21 74.7 0.2 2.6 2 0 0 2 2 2 2 Bromodomain Utp12 PF04003.7 EGO56142.1 - 1e-21 76.8 0.0 1.5e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Nop14 PF04147.7 EGO56142.1 - 0.55 8.0 56.7 0.22 9.3 3.4 2.1 2 0 0 2 2 2 0 Nop14-like family DUF1579 PF07617.6 EGO56144.1 - 0.035 13.7 0.3 0.042 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1579) Pro-kuma_activ PF09286.6 EGO56145.1 - 2.6e-37 128.0 0.1 5e-37 127.1 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGO56145.1 - 1.4e-08 34.2 0.1 7.8e-08 31.8 0.0 2.0 2 0 0 2 2 2 1 Subtilase family Vsr PF03852.10 EGO56145.1 - 0.038 13.6 0.1 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr Rxt3 PF08642.5 EGO56146.1 - 7.2e-24 84.2 0.4 7.2e-24 84.2 0.3 4.5 4 2 0 4 4 4 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EGO56146.1 - 3.6e-05 23.6 0.0 8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 LCCL domain DUF1674 PF07896.7 EGO56147.1 - 3.7e-16 59.0 6.2 8.2e-16 57.9 4.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Pkinase PF00069.20 EGO56148.1 - 9.7e-31 106.8 0.0 3.5e-30 105.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO56148.1 - 1e-16 60.7 0.0 1.5e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO56148.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO56148.1 - 0.085 11.9 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acetyltransf_7 PF13508.1 EGO56149.1 - 0.001 19.1 0.0 0.0024 18.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO56149.1 - 0.0012 18.7 0.3 0.0026 17.7 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EGO56149.1 - 0.0052 16.6 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Lustrin_cystein PF14625.1 EGO56150.1 - 0.018 15.1 0.7 0.025 14.6 0.5 1.4 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain Cellulase PF00150.13 EGO56151.1 - 1.8e-19 69.9 2.8 2.8e-19 69.4 2.0 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EGO56151.1 - 1.1e-05 25.7 0.0 3.5e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 EGO56151.1 - 9.8e-05 21.6 0.2 0.00062 19.0 0.1 2.0 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_2_C PF02836.12 EGO56151.1 - 0.00022 20.2 0.0 0.0013 17.6 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4434 PF14488.1 EGO56151.1 - 0.03 14.0 0.1 0.68 9.6 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4434) Glyco_hydro_10 PF00331.15 EGO56151.1 - 0.04 12.9 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Aminotran_1_2 PF00155.16 EGO56153.1 - 1.3e-93 313.8 0.0 1.5e-93 313.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PolC_DP2 PF03833.8 EGO56153.1 - 0.018 12.7 0.0 0.024 12.3 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Ribosomal_L28 PF00830.14 EGO56154.1 - 1.1e-20 73.1 3.0 1.7e-20 72.5 2.1 1.3 1 0 0 1 1 1 1 Ribosomal L28 family DUF4618 PF15397.1 EGO56155.1 - 0.15 11.3 1.0 0.22 10.8 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Trp_syntA PF00290.15 EGO56156.1 - 1.4e-99 331.8 0.0 3.1e-99 330.7 0.0 1.6 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 EGO56156.1 - 1.3e-44 152.6 0.2 2.3e-44 151.8 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CLN3 PF02487.12 EGO56157.1 - 3.7e-105 352.0 21.5 7.6e-97 324.6 9.2 2.7 1 1 1 2 2 2 2 CLN3 protein MFS_1 PF07690.11 EGO56157.1 - 4.7e-06 25.5 26.6 5.6e-06 25.2 4.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4360 PF14273.1 EGO56158.1 - 0.0012 18.5 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MFS_1 PF07690.11 EGO56159.1 - 6.2e-39 133.6 25.0 8.7e-39 133.2 17.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.20 EGO56160.1 - 6.6e-15 55.4 0.3 1.4e-14 54.3 0.1 1.6 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGO56160.1 - 3.1e-06 26.9 0.1 4.9e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 KR domain IBR PF01485.16 EGO56161.1 - 1.8e-12 46.9 46.5 5.5e-08 32.5 2.0 4.6 4 0 0 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 EGO56161.1 - 0.00022 21.1 8.0 0.00022 21.1 5.6 4.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO56161.1 - 0.01 15.6 9.9 0.01 15.6 6.9 4.8 5 1 0 5 5 5 0 Ring finger domain AMP-binding PF00501.23 EGO56162.1 - 3.2e-62 210.2 0.0 4.7e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EGO56162.1 - 1.7e-14 53.8 0.3 3.5e-14 52.7 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.19 EGO56162.1 - 6.7e-08 31.7 2.9 0.0073 15.7 0.0 6.0 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGO56162.1 - 1.4 8.5 15.0 3.4 7.3 0.6 5.6 6 1 1 7 7 7 0 Hexapeptide repeat of succinyl-transferase F-box PF00646.28 EGO56163.1 - 0.00019 21.0 0.2 0.00019 21.0 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EGO56163.1 - 0.0047 16.6 0.3 0.013 15.2 0.2 1.8 1 0 0 1 1 1 1 F-box-like ADH_N PF08240.7 EGO56164.1 - 4.7e-23 81.0 8.3 7.9e-23 80.2 5.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO56164.1 - 4.8e-17 61.7 0.0 8.6e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 EGO56164.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EGO56164.1 - 0.028 13.5 0.4 0.044 12.9 0.3 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_4 PF01565.18 EGO56165.1 - 1.7e-17 63.2 1.6 3.1e-17 62.3 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGO56165.1 - 2e-11 43.6 0.2 5e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EGO56165.1 - 0.056 12.5 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Pyr_redox_3 PF13738.1 EGO56166.1 - 3.7e-26 92.4 0.0 9.4e-26 91.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO56166.1 - 6.2e-16 58.2 0.0 5.1e-11 42.0 0.0 3.1 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EGO56166.1 - 5.5e-13 47.9 0.0 2e-11 42.8 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EGO56166.1 - 3.1e-10 40.0 0.4 1.7e-07 31.1 0.1 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGO56166.1 - 1.4e-07 31.6 0.0 2.1e-06 27.7 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO56166.1 - 9.7e-07 28.7 0.0 3.1e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGO56166.1 - 6.5e-05 22.1 0.0 0.00016 20.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EGO56166.1 - 0.00014 20.5 0.0 0.014 13.8 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 EGO56166.1 - 0.026 13.6 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.19 EGO56166.1 - 0.029 13.2 0.0 0.11 11.4 0.0 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGO56166.1 - 0.03 13.2 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EGO56166.1 - 0.043 12.6 0.1 0.42 9.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 EGO56166.1 - 0.16 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EGO56166.1 - 0.24 11.8 0.3 22 5.5 0.0 2.8 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EGO56167.1 - 1e-12 47.4 36.2 2e-09 36.6 18.3 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO56167.1 - 0.0004 19.0 16.8 0.0031 16.1 0.8 3.5 2 1 0 3 3 3 3 Sugar (and other) transporter Pyr_redox_3 PF13738.1 EGO56168.1 - 2.9e-25 89.5 0.0 6.4e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGO56168.1 - 7.5e-13 47.5 0.0 4.2e-11 41.7 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EGO56168.1 - 3.7e-10 39.6 0.0 1.2e-09 38.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO56168.1 - 3.2e-05 23.0 0.2 0.023 13.6 0.0 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EGO56168.1 - 0.00014 20.9 0.0 0.91 8.3 0.0 3.6 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGO56168.1 - 0.0014 18.4 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGO56168.1 - 0.013 15.4 0.0 0.059 13.2 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGO56168.1 - 0.029 13.2 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EGO56168.1 - 0.054 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.14 EGO56168.1 - 0.061 12.4 0.0 0.62 9.1 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EGO56168.1 - 0.18 10.6 0.0 0.32 9.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein CBM_20 PF00686.14 EGO56169.1 - 2.9e-33 113.3 0.8 5.5e-33 112.4 0.6 1.5 1 0 0 1 1 1 1 Starch binding domain Chitin_bind_3 PF03067.10 EGO56169.1 - 3.2e-09 37.2 0.2 1.4e-05 25.4 0.0 2.5 1 1 0 2 2 2 2 Chitin binding domain Glyco_hydro_61 PF03443.9 EGO56169.1 - 6.7e-06 26.0 0.1 0.0014 18.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 CBM_25 PF03423.8 EGO56169.1 - 0.029 14.4 0.1 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) bZIP_1 PF00170.16 EGO56171.1 - 2.4e-07 30.5 5.2 6.1e-07 29.3 3.6 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGO56171.1 - 1e-05 25.2 6.4 2.1e-05 24.2 4.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Lebercilin PF15619.1 EGO56171.1 - 0.53 9.6 12.3 0.83 9.0 8.5 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_Maf PF03131.12 EGO56171.1 - 1.3 9.4 11.0 0.058 13.6 3.4 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor Pho88 PF10032.4 EGO56172.1 - 4.8e-79 264.0 0.1 5.4e-79 263.8 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) XPA_C PF05181.7 EGO56173.1 - 3.5e-28 96.9 3.6 3.5e-28 96.9 2.5 2.0 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.13 EGO56173.1 - 3.3e-05 23.4 1.6 3.3e-05 23.4 1.1 1.7 2 0 0 2 2 2 1 XPA protein N-terminal Fer4_10 PF13237.1 EGO56173.1 - 0.067 12.9 4.4 0.79 9.5 0.0 3.1 3 0 0 3 3 3 0 4Fe-4S dicluster domain ArfGap PF01412.13 EGO56173.1 - 0.23 11.2 4.5 0.073 12.8 0.6 2.0 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf zf-ribbon_3 PF13248.1 EGO56173.1 - 3.2 7.0 6.3 11 5.4 1.9 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Fer4_17 PF13534.1 EGO56173.1 - 5.6 7.3 8.3 46 4.4 0.0 3.2 2 1 0 2 2 2 0 4Fe-4S dicluster domain YhfH PF14149.1 EGO56173.1 - 8.8 6.2 14.3 0.96 9.2 0.3 3.1 3 0 0 3 3 3 0 YhfH-like protein Striatin PF08232.7 EGO56174.1 - 1.5e-35 122.4 4.8 1.5e-35 122.4 3.3 2.5 2 0 0 2 2 2 1 Striatin family WD40 PF00400.27 EGO56174.1 - 1.4e-30 103.9 18.1 5.6e-08 32.3 0.0 7.7 7 1 0 7 7 7 5 WD domain, G-beta repeat Polysacc_deac_1 PF01522.16 EGO56174.1 - 0.03 13.9 0.1 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase Het-C PF07217.6 EGO56174.1 - 3.7 5.6 7.2 7.4 4.6 5.0 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C PXA PF02194.10 EGO56174.1 - 4.7 6.7 6.1 12 5.3 0.3 2.2 2 0 0 2 2 2 0 PXA domain PTR2 PF00854.16 EGO56175.1 - 1.6e-27 96.2 0.2 1.5e-26 93.0 0.1 2.4 2 1 0 2 2 2 1 POT family DUF3575 PF12099.3 EGO56175.1 - 0.026 13.5 0.5 0.052 12.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3575) Asp PF00026.18 EGO56177.1 - 2.8e-76 256.7 5.4 3.3e-76 256.5 3.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO56177.1 - 1.5e-07 31.5 0.0 1.7e-06 28.1 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO56177.1 - 0.00023 21.5 1.0 0.0027 18.1 0.2 2.7 2 1 0 2 2 2 1 Aspartyl protease HET PF06985.6 EGO56178.1 - 6.9e-22 78.1 2.1 6.9e-22 78.1 1.5 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) UPF0547 PF10571.4 EGO56178.1 - 0.11 12.2 0.1 0.25 11.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 CTP_transf_2 PF01467.21 EGO56179.1 - 0.028 14.4 0.0 0.43 10.6 0.0 2.5 3 0 0 3 3 3 0 Cytidylyltransferase Acetone_carb_G PF08882.6 EGO56179.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit IZUMO PF15005.1 EGO56180.1 - 0.073 13.1 1.5 0.19 11.7 1.0 1.6 1 1 0 1 1 1 0 Izumo sperm-egg fusion Rubis-subs-bind PF09273.6 EGO56181.1 - 1.1e-21 77.1 0.0 1.9e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EGO56181.1 - 3e-12 47.1 0.0 1.3e-11 45.1 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EGO56181.1 - 1.3e-09 37.7 14.4 2.2e-09 37.0 10.0 1.4 1 0 0 1 1 1 1 MYND finger HET PF06985.6 EGO56183.1 - 3.6e-15 56.3 0.0 7.2e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Suf PF05843.9 EGO56184.1 - 3.8e-05 23.5 4.4 4.1e-05 23.4 3.1 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) FimP PF09766.4 EGO56184.1 - 0.0008 18.5 9.2 0.00094 18.3 6.3 1.1 1 0 0 1 1 1 1 Fms-interacting protein Methyltransf_23 PF13489.1 EGO56184.1 - 0.039 13.6 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Pex16 PF08610.5 EGO56184.1 - 0.08 11.9 5.4 0.095 11.6 3.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF1448 PF07289.6 EGO56184.1 - 0.15 10.9 3.2 0.18 10.7 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1448) DUF775 PF05603.7 EGO56184.1 - 0.2 11.1 6.4 0.24 10.8 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF4175 PF13779.1 EGO56184.1 - 0.22 9.2 19.8 0.26 8.9 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 EGO56184.1 - 0.25 9.5 21.3 0.27 9.4 14.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 EGO56184.1 - 0.59 9.9 11.2 0.69 9.7 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4407 PF14362.1 EGO56184.1 - 0.68 8.8 5.0 0.84 8.5 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.11 EGO56184.1 - 0.89 9.3 5.0 1 9.2 3.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pex14_N PF04695.8 EGO56184.1 - 1.1 9.3 11.9 1.7 8.7 8.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.5 EGO56184.1 - 1.2 7.2 26.0 1.4 6.9 18.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RED_N PF07808.8 EGO56184.1 - 1.3 8.2 10.8 1.7 7.7 7.5 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Serinc PF03348.10 EGO56184.1 - 1.3 7.6 4.1 1.5 7.4 2.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3512 PF12024.3 EGO56184.1 - 1.9 7.6 7.8 11 5.2 3.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) UPF0560 PF10577.4 EGO56184.1 - 2 6.5 11.1 2.2 6.4 7.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 APC_CDC26 PF10471.4 EGO56184.1 - 2.4 8.9 21.3 4.2 8.1 14.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 FCP1_C PF09309.5 EGO56184.1 - 3.5 6.8 10.5 5 6.3 7.3 1.2 1 0 0 1 1 1 0 FCP1, C-terminal BAF1_ABF1 PF04684.8 EGO56184.1 - 4.4 6.0 21.7 4.9 5.8 15.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF605 PF04652.11 EGO56184.1 - 6.5 6.0 15.9 7.9 5.7 11.1 1.0 1 0 0 1 1 1 0 Vta1 like DUF2967 PF11179.3 EGO56184.1 - 8.4 5.7 14.7 9.9 5.5 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Spt20 PF12090.3 EGO56184.1 - 9 5.5 17.2 31 3.8 12.3 1.5 1 1 1 2 2 2 0 Spt20 family TMEM52 PF14979.1 EGO56187.1 - 0.12 12.3 0.2 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 Transmembrane 52 QueT PF06177.6 EGO56187.1 - 4.7 7.1 9.7 37 4.2 6.5 2.6 1 1 1 2 2 2 0 QueT transporter APC10 PF03256.11 EGO56190.1 - 9.6e-47 159.0 0.0 1.4e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PITH PF06201.8 EGO56190.1 - 0.041 13.6 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 PITH domain Mre11_DNA_bind PF04152.9 EGO56192.1 - 1.6e-55 187.6 0.2 1.6e-55 187.6 0.2 2.3 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EGO56192.1 - 3.9e-27 94.9 2.2 6.4e-27 94.2 1.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGO56192.1 - 1.1e-06 28.6 0.1 2.7e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Nucleoplasmin PF03066.10 EGO56192.1 - 3.5 7.1 18.0 0.5 9.8 6.3 3.1 3 0 0 3 3 3 0 Nucleoplasmin DUF4551 PF15087.1 EGO56192.1 - 7 4.8 9.5 11 4.2 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TRAP_alpha PF03896.11 EGO56192.1 - 7.2 5.5 9.5 20 4.0 6.6 1.7 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Shadoo PF14999.1 EGO56192.1 - 8 6.3 13.1 5.8 6.7 0.8 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective TFIID_30kDa PF03540.8 EGO56193.1 - 4.1e-26 90.5 0.4 7.9e-26 89.6 0.3 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Ribosomal_S19 PF00203.16 EGO56194.1 - 2.2e-23 81.6 0.0 3e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Zn_clus PF00172.13 EGO56196.1 - 7.7e-08 32.1 13.6 1.4e-07 31.2 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WXG100 PF06013.7 EGO56198.1 - 0.38 10.7 2.3 3.9 7.5 0.1 2.2 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Cytotoxic PF09000.5 EGO56198.1 - 0.62 10.1 3.7 1 9.3 1.5 2.1 1 1 1 2 2 2 0 Cytotoxic CVNH PF08881.5 EGO56199.1 - 0.00019 21.6 0.0 0.00024 21.2 0.0 1.1 1 0 0 1 1 1 1 CVNH domain CVNH PF08881.5 EGO56200.1 - 0.00016 21.8 0.6 0.094 12.9 0.1 2.3 1 1 1 2 2 2 2 CVNH domain HET PF06985.6 EGO56201.1 - 2.5e-22 79.5 0.1 5e-22 78.5 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nrf1_DNA-bind PF10491.4 EGO56202.1 - 0.024 13.7 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 DUF998 PF06197.8 EGO56202.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Amidase PF01425.16 EGO56204.1 - 2e-66 224.6 0.8 4.7e-65 220.1 0.0 2.3 2 0 0 2 2 2 2 Amidase F-box-like PF12937.2 EGO56206.1 - 0.00088 18.9 0.7 0.0033 17.1 0.5 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO56206.1 - 0.0042 16.7 2.2 0.014 15.0 1.5 1.9 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 EGO56206.1 - 0.024 14.2 0.0 20 4.9 0.0 3.8 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) p450 PF00067.17 EGO56207.1 - 3.5e-48 164.2 0.0 1.4e-47 162.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EGO56208.1 - 3e-41 141.2 28.4 4.1e-41 140.8 19.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2142 PF09913.4 EGO56208.1 - 0.00013 20.7 9.5 0.0031 16.2 5.4 2.8 1 1 1 2 2 2 2 Predicted membrane protein (DUF2142) DUF2939 PF11159.3 EGO56210.1 - 0.47 10.6 3.9 0.54 10.4 0.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2939) DUF1992 PF09350.5 EGO56211.1 - 3.4e-25 87.6 0.5 1.1e-24 85.9 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DUF1741 PF08427.5 EGO56214.1 - 9.2e-88 293.6 0.1 3.9e-87 291.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Fe-S_biosyn PF01521.15 EGO56215.1 - 2.4e-19 69.3 0.0 3.2e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Mitofilin PF09731.4 EGO56215.1 - 0.029 13.0 2.6 0.031 12.9 1.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TFIIA PF03153.8 EGO56215.1 - 3.2 7.5 16.4 3.9 7.2 11.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 EGO56215.1 - 8 5.7 29.5 13 5.0 20.4 1.3 1 0 0 1 1 1 0 Vta1 like MgsA_C PF12002.3 EGO56216.1 - 3.2e-60 202.6 0.0 5e-60 202.0 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EGO56216.1 - 6.9e-13 48.9 0.0 1.3e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGO56216.1 - 1.6e-09 37.2 0.0 4.3e-09 35.7 0.0 1.6 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 EGO56216.1 - 4.7e-06 26.1 0.0 0.00028 20.4 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 EGO56216.1 - 0.00021 21.4 0.8 0.0019 18.3 0.6 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGO56216.1 - 0.00024 20.9 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO56216.1 - 0.00049 20.1 0.6 0.007 16.3 0.4 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGO56216.1 - 0.00059 19.5 0.1 0.0021 17.7 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EGO56216.1 - 0.00082 19.1 0.1 0.039 13.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGO56216.1 - 0.0011 18.1 0.0 0.57 9.3 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI DNA_pol3_delta2 PF13177.1 EGO56216.1 - 0.002 17.8 0.0 0.058 13.0 0.0 2.3 1 1 1 2 2 2 1 DNA polymerase III, delta subunit DUF815 PF05673.8 EGO56216.1 - 0.0025 16.8 0.0 0.0042 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EGO56216.1 - 0.0028 18.4 0.0 0.006 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGO56216.1 - 0.015 14.7 0.3 4.4 6.6 0.0 2.7 1 1 0 2 2 2 0 AAA-like domain TIP49 PF06068.8 EGO56216.1 - 0.02 13.6 0.0 0.045 12.4 0.0 1.5 2 0 0 2 2 2 0 TIP49 C-terminus ResIII PF04851.10 EGO56216.1 - 0.02 14.7 0.5 2.8 7.7 0.0 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_3 PF07726.6 EGO56216.1 - 0.033 13.7 0.0 0.11 12.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 EGO56216.1 - 0.037 13.9 0.1 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_18 PF13238.1 EGO56216.1 - 0.047 13.9 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGO56216.1 - 0.071 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 EGO56216.1 - 0.096 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein HeLo PF14479.1 EGO56217.1 - 1.4e-49 168.7 0.0 1.4e-49 168.7 0.0 1.7 2 0 0 2 2 2 1 Prion-inhibition and propagation NACHT PF05729.7 EGO56217.1 - 1.3e-07 31.4 0.0 6.9e-07 29.0 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EGO56217.1 - 4.7e-05 23.5 0.0 0.00019 21.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO56217.1 - 0.0001 22.3 0.2 0.00098 19.1 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 EGO56217.1 - 0.005 16.0 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGO56217.1 - 0.03 15.1 0.0 0.13 13.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGO56217.1 - 0.031 14.5 0.0 0.099 12.9 0.0 1.9 2 0 0 2 2 1 0 ABC transporter RNA_helicase PF00910.17 EGO56217.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EGO56217.1 - 0.059 12.2 0.0 0.47 9.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 EGO56217.1 - 0.083 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EGO56217.1 - 0.089 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EGO56217.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGO56217.1 - 0.13 11.6 0.1 0.39 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain Pyrophosphatase PF00719.14 EGO56219.1 - 1.5e-48 164.1 0.0 2.1e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase SR-25 PF10500.4 EGO56219.1 - 0.059 12.8 18.8 0.097 12.1 13.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIE-A_C-term PF11521.3 EGO56219.1 - 1.4 8.8 0.0 1.4 8.8 0.0 3.5 3 1 1 4 4 4 0 C-terminal general transcription factor TFIIE alpha Apt1 PF10351.4 EGO56219.1 - 3.1 6.5 8.2 4.3 6.0 5.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CAF-1_p150 PF11600.3 EGO56219.1 - 8.1 5.7 7.7 15 4.9 5.3 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF755 PF05501.6 EGO56219.1 - 8.8 6.4 23.0 15 5.6 15.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF3512 PF12024.3 EGO56220.1 - 0.32 10.2 12.1 0.37 10.0 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) MMR_HSR1 PF01926.18 EGO56221.1 - 1.8e-05 24.6 0.0 6e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGO56221.1 - 0.00058 19.0 0.0 0.0018 17.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGO56221.1 - 0.00091 18.7 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain fn3 PF00041.16 EGO56221.1 - 0.0023 18.0 0.0 0.016 15.3 0.0 2.3 2 0 0 2 2 2 1 Fibronectin type III domain ABC_tran PF00005.22 EGO56221.1 - 0.017 15.4 0.2 0.15 12.3 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 EGO56221.1 - 0.081 13.2 0.0 0.081 13.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGO56221.1 - 0.11 12.4 1.8 1 9.2 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain V_ATPase_I PF01496.14 EGO56222.1 - 0.91 7.2 5.3 1.3 6.8 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 EGO56222.1 - 1.3 9.2 8.2 2.3 8.4 5.7 1.4 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EGO56222.1 - 4.8 6.1 11.5 8.8 5.2 8.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Microtub_assoc PF07989.6 EGO56222.1 - 5 7.0 14.4 9.7 6.0 8.7 2.5 1 1 1 2 2 2 0 Microtubule associated adh_short PF00106.20 EGO56224.1 - 6.5e-17 61.9 0.5 1.2e-16 61.1 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO56224.1 - 5.1e-08 32.7 0.3 5.2e-07 29.5 0.0 2.1 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EGO56224.1 - 0.045 13.1 0.1 0.11 11.8 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CorA PF01544.13 EGO56225.1 - 1.1e-10 41.0 0.3 2.5e-10 39.8 0.2 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2427 PF10348.4 EGO56228.1 - 7.2e-07 28.7 4.5 1.5e-06 27.7 3.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 EGO56228.1 - 2.1e-06 27.5 14.5 2.1e-06 27.5 10.1 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 7TMR-DISM_7TM PF07695.6 EGO56228.1 - 1.6 8.3 10.3 1.2 8.7 3.6 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF1040 PF06288.8 EGO56230.1 - 0.025 14.7 1.7 0.06 13.5 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1040) FLO_LFY PF01698.11 EGO56231.1 - 0.12 11.2 0.1 0.18 10.5 0.1 1.3 1 1 0 1 1 1 0 Floricaula / Leafy protein LisH PF08513.6 EGO56234.1 - 0.03 14.0 0.2 0.082 12.7 0.0 1.8 2 0 0 2 2 2 0 LisH Hydrophobin PF01185.13 EGO56236.1 - 0.22 11.9 10.5 3.7 8.0 7.5 2.1 1 1 1 2 2 2 0 Fungal hydrophobin AIP3 PF03915.8 EGO56243.1 - 6.1e-169 562.4 9.8 1e-168 561.6 6.8 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 EGO56243.1 - 0.0085 15.4 0.2 0.0085 15.4 0.1 3.1 4 0 0 4 4 4 1 Hepatic lectin, N-terminal domain FliL PF03748.9 EGO56243.1 - 0.012 15.6 1.7 0.024 14.6 0.1 2.4 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL Syntaxin_2 PF14523.1 EGO56243.1 - 0.28 11.2 8.9 8.7 6.4 0.0 4.6 3 1 1 4 4 4 0 Syntaxin-like protein Thymidylat_synt PF00303.14 EGO56243.1 - 0.32 9.9 2.8 0.41 9.6 0.0 2.3 2 1 1 3 3 3 0 Thymidylate synthase DUF1664 PF07889.7 EGO56243.1 - 1.9 8.3 11.2 9.5 6.0 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Beta-lactamase PF00144.19 EGO56244.1 - 6.4e-30 104.2 1.5 1.2e-29 103.3 1.1 1.4 1 1 0 1 1 1 1 Beta-lactamase HET PF06985.6 EGO56245.1 - 0.0001 22.4 0.1 0.00011 22.3 0.1 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ATP-grasp_2 PF08442.5 EGO56246.1 - 9.5e-79 263.4 0.4 1.7e-78 262.6 0.3 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EGO56246.1 - 3.3e-26 91.7 0.2 5.9e-26 90.8 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EGO56246.1 - 1.6e-09 37.3 0.1 3.9e-09 36.0 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EGO56246.1 - 0.0085 15.6 0.5 0.22 11.0 0.1 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EGO56246.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain stn_TNFRSF12A PF12191.3 EGO56247.1 - 0.065 13.2 0.2 0.73 9.8 0.0 2.3 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Serglycin PF04360.7 EGO56247.1 - 7.2 6.3 9.9 2.8 7.6 4.8 1.8 2 0 0 2 2 2 0 Serglycin HET PF06985.6 EGO56248.1 - 3.2e-21 75.9 7.8 2.2e-18 66.7 0.7 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_71 PF03659.9 EGO56249.1 - 2.2e-142 474.0 6.3 3.9e-142 473.2 4.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 HET PF06985.6 EGO56250.1 - 0.0015 18.6 0.1 0.0017 18.5 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribosomal_60s PF00428.14 EGO56251.1 - 0.0065 16.8 4.3 0.012 16.0 3.0 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein SET PF00856.23 EGO56251.1 - 0.011 16.0 0.4 0.028 14.7 0.0 1.8 2 1 0 2 2 2 0 SET domain MAP PF03642.8 EGO56251.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.7 2 0 0 2 2 2 0 MAP domain Ras PF00071.17 EGO56253.1 - 1.6e-65 219.4 0.6 1.9e-65 219.2 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO56253.1 - 1.2e-21 77.4 0.0 1.7e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO56253.1 - 2.3e-16 59.5 0.1 2.8e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGO56253.1 - 1.3e-05 24.6 0.2 2.9e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGO56253.1 - 1.6e-05 24.1 0.1 2.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGO56253.1 - 6.4e-05 22.8 0.0 0.00015 21.7 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGO56253.1 - 0.00038 19.7 0.0 0.00063 18.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 EGO56253.1 - 0.001 19.2 0.1 0.08 13.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO56253.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EGO56253.1 - 0.0022 17.2 0.1 0.015 14.5 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EGO56253.1 - 0.0052 15.9 0.0 0.014 14.6 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EGO56253.1 - 0.019 14.8 0.2 0.06 13.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGO56253.1 - 0.02 14.9 0.1 0.084 12.8 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EGO56253.1 - 0.038 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 EGO56253.1 - 0.049 12.6 0.1 0.21 10.5 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_5 PF07728.9 EGO56253.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EGO56253.1 - 0.088 13.1 0.0 0.14 12.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EGO56253.1 - 0.098 12.1 0.1 0.95 8.9 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3807 PF12720.2 EGO56254.1 - 0.00093 19.4 23.7 0.0011 19.1 16.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) YL1 PF05764.8 EGO56254.1 - 0.0042 16.7 38.0 0.0052 16.4 26.4 1.2 1 0 0 1 1 1 1 YL1 nuclear protein DUF2201_N PF13203.1 EGO56254.1 - 0.0044 16.2 11.2 0.0049 16.0 7.8 1.1 1 0 0 1 1 1 1 Putative metallopeptidase domain RR_TM4-6 PF06459.7 EGO56254.1 - 0.04 13.7 23.7 0.059 13.2 16.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.5 EGO56254.1 - 0.044 13.8 38.8 0.055 13.4 26.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ycf1 PF05758.7 EGO56254.1 - 0.05 11.3 20.3 0.056 11.1 14.1 1.0 1 0 0 1 1 1 0 Ycf1 Tim54 PF11711.3 EGO56254.1 - 0.076 11.5 15.6 0.1 11.1 10.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SET PF00856.23 EGO56254.1 - 0.097 12.9 4.8 0.13 12.5 3.3 1.4 1 0 0 1 1 1 0 SET domain CDC45 PF02724.9 EGO56254.1 - 0.1 10.5 20.6 0.13 10.2 14.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 EGO56254.1 - 0.12 11.4 7.0 0.13 11.2 4.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.10 EGO56254.1 - 0.12 11.0 7.3 0.14 10.8 5.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Glypican PF01153.14 EGO56254.1 - 0.13 10.8 9.0 0.17 10.4 6.3 1.0 1 0 0 1 1 1 0 Glypican FLO_LFY PF01698.11 EGO56254.1 - 0.18 10.6 20.1 0.25 10.1 14.0 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DDHD PF02862.12 EGO56254.1 - 0.21 11.3 17.1 0.28 10.9 11.8 1.2 1 0 0 1 1 1 0 DDHD domain LicD PF04991.8 EGO56254.1 - 0.26 11.3 17.0 0.34 10.9 11.8 1.3 1 0 0 1 1 1 0 LicD family RP-C_C PF11800.3 EGO56254.1 - 0.34 10.6 8.4 0.36 10.4 5.8 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Raftlin PF15250.1 EGO56254.1 - 0.34 9.3 15.9 0.46 8.9 11.1 1.2 1 0 0 1 1 1 0 Raftlin Gag_spuma PF03276.9 EGO56254.1 - 0.43 8.8 9.7 0.48 8.6 6.7 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Folate_carrier PF01770.13 EGO56254.1 - 0.51 8.7 8.8 0.64 8.4 6.1 1.3 1 0 0 1 1 1 0 Reduced folate carrier BSMAP PF12280.3 EGO56254.1 - 0.6 9.9 9.0 0.85 9.4 6.2 1.3 1 0 0 1 1 1 0 Brain specific membrane anchored protein SAPS PF04499.10 EGO56254.1 - 0.65 8.5 14.4 0.76 8.3 10.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DHHW PF14286.1 EGO56254.1 - 0.74 9.0 8.3 0.89 8.8 5.8 1.0 1 0 0 1 1 1 0 DHHW protein DUF1510 PF07423.6 EGO56254.1 - 1.2 8.4 32.0 1.6 8.0 22.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF262 PF03235.9 EGO56254.1 - 1.2 9.0 13.7 1.5 8.7 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Neur_chan_memb PF02932.11 EGO56254.1 - 1.3 8.8 14.7 1.5 8.6 10.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TraH_2 PF06871.6 EGO56254.1 - 1.3 8.4 6.2 1.8 7.9 4.3 1.2 1 0 0 1 1 1 0 TraH_2 Herpes_env PF01673.13 EGO56254.1 - 1.5 7.2 9.7 1.6 7.1 6.7 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Glyco_transf_15 PF01793.11 EGO56254.1 - 1.5 7.6 15.5 1.8 7.4 10.8 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Band_3_cyto PF07565.8 EGO56254.1 - 2.3 7.6 14.6 2.9 7.3 10.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF913 PF06025.7 EGO56254.1 - 2.6 6.7 7.9 2.8 6.5 5.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.2 EGO56254.1 - 2.6 5.5 13.8 2.8 5.5 9.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4220 PF13968.1 EGO56254.1 - 2.8 6.9 8.8 3 6.8 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF2413 PF10310.4 EGO56254.1 - 3 6.5 30.1 3.6 6.3 20.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF4557 PF15101.1 EGO56254.1 - 3.1 7.5 13.3 4.2 7.1 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Paramyxo_ncap PF00973.14 EGO56254.1 - 3.3 6.2 16.0 4.1 5.9 11.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Apt1 PF10351.4 EGO56254.1 - 3.4 6.4 23.5 4.1 6.1 16.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SprA-related PF12118.3 EGO56254.1 - 3.8 6.7 23.3 4.7 6.4 16.1 1.1 1 0 0 1 1 1 0 SprA-related family MDFI PF15316.1 EGO56254.1 - 4 7.3 10.5 5 7.0 7.3 1.2 1 0 0 1 1 1 0 MyoD family inhibitor YqfQ PF14181.1 EGO56254.1 - 5.6 6.9 40.5 60 3.6 28.1 2.1 1 1 0 1 1 1 0 YqfQ-like protein MIP-T3 PF10243.4 EGO56254.1 - 6.1 5.1 55.9 7.7 4.8 38.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SID-1_RNA_chan PF13965.1 EGO56254.1 - 7 4.6 6.0 7.2 4.6 4.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 eIF-3_zeta PF05091.7 EGO56254.1 - 8.4 4.8 21.1 9.3 4.7 14.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) HSF_DNA-bind PF00447.12 EGO56258.1 - 4.1e-22 78.2 1.8 7.8e-20 70.9 0.2 2.4 1 1 1 2 2 2 2 HSF-type DNA-binding DUF4262 PF14081.1 EGO56260.1 - 0.11 12.6 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) WD40 PF00400.27 EGO56261.1 - 2.2e-26 90.7 3.1 2.6e-08 33.4 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF3639 PF12341.3 EGO56261.1 - 5.7e-09 35.8 1.0 5.7e-09 35.8 0.7 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 EGO56261.1 - 1.1e-05 24.4 0.0 2.2e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.6 EGO56261.1 - 2e-05 24.4 0.0 0.002 17.8 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EGO56261.1 - 0.0066 15.9 0.0 5.8 6.4 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EGO56261.1 - 0.04 11.7 0.0 0.077 10.7 0.0 1.5 1 0 0 1 1 1 0 IKI3 family DNA_pol_alpha_N PF12254.3 EGO56261.1 - 0.054 13.3 5.0 0.2 11.5 3.4 2.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal ToxN_toxin PF13958.1 EGO56261.1 - 0.29 10.7 0.0 0.47 10.1 0.0 1.2 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system WD40 PF00400.27 EGO56262.1 - 8.2e-18 63.5 19.2 0.00015 21.4 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF627 PF04781.7 EGO56262.1 - 0.002 17.7 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF627) Nup160 PF11715.3 EGO56262.1 - 0.0037 15.4 1.1 2.1 6.3 0.0 3.1 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Sigma70_r1_2 PF00140.15 EGO56262.1 - 0.071 12.7 0.3 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 PQQ_3 PF13570.1 EGO56262.1 - 0.11 12.8 1.4 1.7 9.0 0.1 3.4 3 0 0 3 3 3 0 PQQ-like domain MSP1_C PF07462.6 EGO56264.1 - 0.32 9.3 0.7 0.6 8.4 0.5 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Nucleoplasmin PF03066.10 EGO56264.1 - 1.1 8.8 4.7 0.19 11.2 0.5 1.7 2 0 0 2 2 2 0 Nucleoplasmin Nramp PF01566.13 EGO56266.1 - 2e-71 240.6 11.0 2e-71 240.6 7.6 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein DUF3227 PF11537.3 EGO56266.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3227) Na_Ca_ex PF01699.19 EGO56267.1 - 6.6e-31 106.7 35.3 5.7e-16 58.3 9.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2457 PF10446.4 EGO56267.1 - 0.0067 15.2 13.0 0.0089 14.8 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CDC45 PF02724.9 EGO56267.1 - 0.0077 14.3 1.2 0.0098 13.9 0.8 1.1 1 0 0 1 1 1 1 CDC45-like protein YfhO PF09586.5 EGO56267.1 - 0.018 13.0 0.5 0.094 10.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial membrane protein YfhO PGK PF00162.14 EGO56267.1 - 0.057 11.9 0.1 0.087 11.3 0.1 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase Nop14 PF04147.7 EGO56267.1 - 0.5 8.2 8.6 0.73 7.6 6.0 1.1 1 0 0 1 1 1 0 Nop14-like family FA_desaturase PF00487.19 EGO56267.1 - 1.2 8.5 5.4 1.6 8.1 0.0 2.4 3 0 0 3 3 3 0 Fatty acid desaturase DUF788 PF05620.6 EGO56267.1 - 1.3 8.9 4.4 11 5.8 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF788) SDA1 PF05285.7 EGO56267.1 - 9.6 5.3 10.8 13 4.9 7.5 1.1 1 0 0 1 1 1 0 SDA1 Pol_alpha_B_N PF08418.5 EGO56268.1 - 0.36 10.3 3.5 0.37 10.2 2.4 1.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RabGAP-TBC PF00566.13 EGO56273.1 - 8.9e-48 162.5 0.4 1.7e-46 158.4 0.1 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain HALZ PF02183.13 EGO56273.1 - 0.017 14.8 18.2 0.16 11.6 0.4 4.4 2 2 2 4 4 4 0 Homeobox associated leucine zipper DUF1640 PF07798.6 EGO56273.1 - 0.043 13.8 14.6 1.1 9.2 9.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) GP41 PF00517.12 EGO56273.1 - 0.073 12.6 3.6 0.18 11.3 2.5 1.6 1 0 0 1 1 1 0 Retroviral envelope protein CCDC155 PF14662.1 EGO56273.1 - 0.083 12.4 37.1 0.039 13.5 6.7 3.2 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 Ribosomal_S8e PF01201.17 EGO56274.1 - 1.8e-49 167.2 1.3 2.1e-49 167.0 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e DUF913 PF06025.7 EGO56275.1 - 3.3e-104 348.6 0.0 3.3e-104 348.6 0.0 4.5 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 EGO56275.1 - 8.1e-103 344.1 0.0 8.1e-103 344.1 0.0 3.7 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) HECT PF00632.20 EGO56275.1 - 5.7e-96 321.3 0.0 1.1e-95 320.5 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4414 PF14377.1 EGO56275.1 - 9.5e-33 112.3 5.2 9.5e-33 112.3 3.6 4.1 3 1 0 3 3 3 1 Domain of unknown function (DUF4414) Ribosomal_S6e PF01092.14 EGO56277.1 - 2.1e-61 205.1 0.1 3.8e-61 204.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Cadherin_C PF01049.12 EGO56277.1 - 0.13 12.3 0.2 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic region Diphthamide_syn PF01866.12 EGO56278.1 - 6.3e-112 373.7 0.0 7.6e-112 373.5 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein PPR_2 PF13041.1 EGO56279.1 - 0.023 14.6 0.0 2 8.4 0.0 3.3 4 0 0 4 4 4 0 PPR repeat family DUF866 PF05907.8 EGO56280.1 - 4.8e-51 172.4 0.4 5.2e-51 172.3 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cas_CXXC_CXXC PF09706.5 EGO56280.1 - 0.024 14.7 1.3 0.12 12.6 1.1 1.9 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) DUF3716 PF12511.3 EGO56280.1 - 0.049 13.2 2.2 0.092 12.3 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) PHD PF00628.24 EGO56280.1 - 0.06 13.0 0.7 0.14 11.9 0.5 1.6 1 0 0 1 1 1 0 PHD-finger Lar_restr_allev PF14354.1 EGO56280.1 - 0.12 12.6 1.6 2.3 8.5 0.0 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EGO56280.1 - 2.6 7.9 5.4 9.5 6.1 3.8 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGO56280.1 - 2.8 7.6 5.3 2.4 7.8 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGO56280.1 - 4.7 6.9 6.0 3.6 7.3 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Rpr2 PF04032.11 EGO56281.1 - 7.6e-14 51.3 0.2 1.4e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.1 EGO56281.1 - 0.015 15.0 1.7 0.45 10.2 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal zf-ZPR1 PF03367.8 EGO56282.1 - 3.1e-103 341.7 0.4 1.7e-50 170.3 0.0 2.6 2 1 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 EGO56282.1 - 0.24 11.0 3.0 3.5 7.3 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family tRNA_int_end_N2 PF12928.2 EGO56284.1 - 6.1e-13 48.0 0.5 1.3e-12 46.9 0.3 1.6 1 1 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Ribosomal_60s PF00428.14 EGO56284.1 - 0.019 15.3 0.7 0.019 15.3 0.5 3.3 4 0 0 4 4 4 0 60s Acidic ribosomal protein tRNA_int_endo_N PF02778.9 EGO56284.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Arrestin_C PF02752.17 EGO56285.1 - 2.2e-16 60.1 0.0 4.7e-15 55.8 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.16 EGO56287.1 - 3.3e-43 147.5 0.0 3.8e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GGDEF PF00990.16 EGO56287.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 GGDEF domain HSF_DNA-bind PF00447.12 EGO56288.1 - 6.8e-28 96.8 0.1 1.9e-27 95.4 0.1 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding RIH_assoc PF08454.6 EGO56288.1 - 0.33 10.6 7.4 0.62 9.7 5.1 1.4 1 0 0 1 1 1 0 RyR and IP3R Homology associated DUF904 PF06005.7 EGO56288.1 - 0.51 10.6 6.4 6.9 7.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Nup54 PF13874.1 EGO56288.1 - 6.2 6.4 10.7 0.039 13.6 0.8 2.2 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 Pro_isomerase PF00160.16 EGO56290.1 - 1.7e-42 145.2 0.0 3.4e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP-synt_ab PF00006.20 EGO56291.1 - 4.1e-60 202.9 0.0 5.3e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGO56291.1 - 3.1e-16 59.8 0.0 5.4e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGO56291.1 - 1.3e-12 47.7 0.9 2.6e-12 46.7 0.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EGO56291.1 - 0.00046 20.0 0.4 0.00097 18.9 0.3 1.5 1 0 0 1 1 1 1 HAS barrel domain Aldose_epim PF01263.15 EGO56292.1 - 1.6e-40 139.0 0.0 3.8e-40 137.8 0.0 1.5 1 1 0 1 1 1 1 Aldose 1-epimerase RRM_1 PF00076.17 EGO56294.1 - 1.6e-14 53.2 0.0 3.8e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO56294.1 - 1.8e-12 47.0 0.0 3.6e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO56294.1 - 1.9e-09 37.2 0.0 4.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRAB PF10375.4 EGO56295.1 - 3e-08 32.9 0.0 5.6e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Myosin_tail_1 PF01576.14 EGO56295.1 - 0.00033 18.5 63.5 0.00047 18.0 44.0 1.1 1 0 0 1 1 1 1 Myosin tail Tup_N PF08581.5 EGO56295.1 - 0.0014 18.8 3.2 0.0014 18.8 2.2 4.2 1 1 2 4 4 4 1 Tup N-terminal Filament PF00038.16 EGO56295.1 - 0.06 12.8 60.5 0.39 10.1 23.5 2.4 1 1 1 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 EGO56295.1 - 0.37 9.9 14.4 4.9 6.2 5.8 2.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EGO56295.1 - 0.44 10.3 13.8 0.28 11.0 2.2 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.8 EGO56295.1 - 0.55 10.0 6.7 2.4 7.9 0.2 3.6 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Fib_alpha PF08702.5 EGO56295.1 - 0.61 10.2 31.9 0.34 11.0 8.6 3.5 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Cytokin-bind PF09265.5 EGO56295.1 - 1.3 8.0 4.6 0.62 9.1 0.4 2.2 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding AAA_13 PF13166.1 EGO56295.1 - 1.3 7.3 44.7 0.24 9.7 18.0 2.2 1 1 1 2 2 2 0 AAA domain Cast PF10174.4 EGO56295.1 - 1.6 6.7 67.0 0.09 10.8 20.9 2.1 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone Laminin_I PF06008.9 EGO56295.1 - 2.5 7.3 52.5 0.51 9.5 12.4 3.8 1 1 3 4 4 4 0 Laminin Domain I Imm42 PF15601.1 EGO56295.1 - 6.7 6.1 10.1 3.5 7.0 0.4 3.6 3 2 1 4 4 4 0 Immunity protein 42 Spc7 PF08317.6 EGO56295.1 - 9.2 4.8 52.8 0.37 9.4 14.9 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein CHD5 PF04420.9 EGO56297.1 - 2.1e-63 212.7 1.2 2.1e-63 212.7 0.8 1.4 2 0 0 2 2 2 1 CHD5-like protein Myosin_tail_1 PF01576.14 EGO56297.1 - 0.0014 16.4 5.5 0.002 15.9 3.8 1.1 1 0 0 1 1 1 1 Myosin tail PV-1 PF06637.6 EGO56297.1 - 0.0032 16.0 0.1 0.0046 15.5 0.1 1.3 1 0 0 1 1 1 1 PV-1 protein (PLVAP) DUF4279 PF14106.1 EGO56297.1 - 0.1 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) DUF677 PF05055.7 EGO56297.1 - 0.23 10.0 2.0 0.5 8.9 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF677) DUF4446 PF14584.1 EGO56297.1 - 0.43 10.3 2.6 0.9 9.3 0.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) PcfJ PF14284.1 EGO56297.1 - 1.4 8.3 4.7 0.26 10.7 0.5 1.7 2 0 0 2 2 2 0 PcfJ-like protein PPTA PF01239.17 EGO56298.1 - 5.1e-05 22.4 12.4 0.0029 16.8 0.3 4.4 5 0 0 5 5 5 2 Protein prenyltransferase alpha subunit repeat Asp PF00026.18 EGO56300.1 - 5.3e-65 219.7 3.2 7e-65 219.3 2.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO56300.1 - 1.4e-07 31.6 0.1 1.4e-07 31.6 0.1 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO56300.1 - 0.0061 17.0 2.4 0.11 13.0 0.0 3.5 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 EGO56300.1 - 0.071 12.6 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Aa_trans PF01490.13 EGO56301.1 - 6e-74 248.9 22.5 7.5e-74 248.6 15.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NTP_transf_2 PF01909.18 EGO56302.1 - 0.0075 16.5 0.0 0.0078 16.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain Ras PF00071.17 EGO56303.1 - 4.2e-56 188.8 0.0 4.9e-56 188.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO56303.1 - 9.5e-15 55.1 0.0 1.4e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO56303.1 - 1.1e-07 31.2 0.0 1.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGO56303.1 - 0.0012 18.1 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGO56303.1 - 0.019 14.1 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region KOW PF00467.24 EGO56304.1 - 3.1e-05 23.5 0.1 8.1e-05 22.1 0.1 1.7 1 0 0 1 1 1 1 KOW motif YajC PF02699.10 EGO56304.1 - 0.1 12.2 0.1 0.36 10.5 0.1 1.9 1 0 0 1 1 1 0 Preprotein translocase subunit IKI3 PF04762.7 EGO56305.1 - 0 1104.5 0.0 0 1104.2 0.0 1.1 1 0 0 1 1 1 1 IKI3 family TPR_8 PF13181.1 EGO56305.1 - 0.016 14.9 0.1 0.052 13.3 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGO56305.1 - 0.017 14.7 0.3 0.054 13.1 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGO56305.1 - 0.85 9.6 4.1 0.4 10.7 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3984 PF13136.1 EGO56306.1 - 9e-66 222.3 35.0 2.3e-64 217.7 19.1 3.6 2 1 0 2 2 2 2 Protein of unknown function (DUF3984) Hpt PF01627.18 EGO56307.1 - 4e-11 42.7 0.0 6.7e-11 42.0 0.0 1.4 1 1 0 1 1 1 1 Hpt domain DUF1804 PF08822.6 EGO56307.1 - 0.047 13.4 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Endonuc-BsobI PF09194.5 EGO56307.1 - 0.099 11.5 0.8 1.4 7.7 0.2 2.0 1 1 0 2 2 2 0 Restriction endonuclease BsobI AKAP7_NLS PF10469.4 EGO56308.1 - 1.2e-25 90.4 0.0 2.4e-19 69.8 0.0 2.3 2 1 0 2 2 2 2 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 EGO56308.1 - 0.034 13.8 0.0 0.059 13.0 0.0 1.5 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily BAF1_ABF1 PF04684.8 EGO56308.1 - 4.7 5.9 5.7 6.1 5.5 4.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TPR_MLP1_2 PF07926.7 EGO56309.1 - 0.0001 22.0 2.7 0.0001 22.0 1.9 1.9 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein IncA PF04156.9 EGO56309.1 - 0.0077 15.8 2.2 0.015 14.8 1.5 1.5 1 0 0 1 1 1 1 IncA protein UPF0149 PF03695.8 EGO56309.1 - 0.01 15.7 1.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) Tropomyosin_1 PF12718.2 EGO56309.1 - 0.013 15.2 1.3 0.013 15.2 0.9 2.2 3 0 0 3 3 3 0 Tropomyosin like TMF_TATA_bd PF12325.3 EGO56309.1 - 0.038 13.7 1.7 0.1 12.2 1.2 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding EzrA PF06160.7 EGO56309.1 - 0.068 11.3 2.3 0.12 10.5 1.6 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TMF_DNA_bd PF12329.3 EGO56309.1 - 0.091 12.5 2.4 5.1 6.9 0.4 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding OmpH PF03938.9 EGO56309.1 - 0.23 11.3 4.8 0.62 9.9 0.7 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Lebercilin PF15619.1 EGO56309.1 - 0.26 10.7 9.4 0.1 11.9 4.7 1.7 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DP PF08781.5 EGO56309.1 - 0.29 10.7 2.3 5.1 6.7 0.3 2.3 2 0 0 2 2 2 0 Transcription factor DP HR1 PF02185.11 EGO56309.1 - 0.46 10.2 4.0 0.28 10.9 0.9 2.1 2 0 0 2 2 2 0 Hr1 repeat Spc7 PF08317.6 EGO56309.1 - 0.53 8.8 7.4 0.061 11.9 1.4 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.4 EGO56309.1 - 6.4 5.6 9.5 1.1 8.1 2.9 1.9 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 SSFA2_C PF14723.1 EGO56309.1 - 8.9 6.0 7.5 1.1e+02 2.4 5.2 2.3 1 1 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF4117 PF13491.1 EGO56312.1 - 0.034 13.5 1.7 0.036 13.5 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4117) Sugar_tr PF00083.19 EGO56313.1 - 1.7e-93 313.6 23.2 2.1e-93 313.3 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO56313.1 - 2.1e-21 76.0 48.5 3.3e-20 72.1 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Stc1 PF12898.2 EGO56315.1 - 5.8e-19 67.9 6.8 1.1e-18 67.1 4.7 1.4 1 0 0 1 1 1 1 Stc1 domain Pkinase PF00069.20 EGO56316.1 - 1.5e-59 201.2 0.0 2.2e-59 200.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO56316.1 - 4e-32 111.3 0.0 1.2e-30 106.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EGO56316.1 - 0.022 13.5 0.0 0.031 13.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HSP70 PF00012.15 EGO56317.1 - 6.1e-12 44.2 0.6 4.4e-11 41.4 0.0 1.9 2 0 0 2 2 2 2 Hsp70 protein AAA_17 PF13207.1 EGO56318.1 - 2.3e-06 28.3 0.2 1.8e-05 25.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EGO56318.1 - 0.00054 20.2 0.1 0.0089 16.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain CPT PF07931.7 EGO56318.1 - 0.0009 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein PRK PF00485.13 EGO56318.1 - 0.0039 16.7 0.0 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 EGO56318.1 - 0.02 14.8 0.6 0.063 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain PTH2 PF01981.11 EGO56319.1 - 7.3e-48 161.0 0.2 1e-47 160.5 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Hom_end PF05204.9 EGO56319.1 - 0.059 13.3 0.5 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 Homing endonuclease BING4CT PF08149.6 EGO56320.1 - 5.8e-41 137.8 0.0 2.4e-37 126.2 0.0 3.2 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 EGO56320.1 - 3.6e-09 36.1 0.0 3.3e-05 23.5 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EGO56320.1 - 0.0087 14.3 0.0 2.4 6.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 EGO56320.1 - 0.016 13.9 0.0 0.044 12.5 0.0 1.5 1 1 0 1 1 1 0 Coatomer WD associated region PHO4 PF01384.15 EGO56320.1 - 0.13 10.9 0.1 0.18 10.4 0.1 1.2 1 0 0 1 1 1 0 Phosphate transporter family DUF663 PF04950.7 EGO56321.1 - 2.7e-112 374.5 0.0 4.1e-112 373.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EGO56321.1 - 5.7e-18 64.2 0.0 1.4e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EGO56321.1 - 0.022 14.1 0.0 0.082 12.3 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RRM_6 PF14259.1 EGO56321.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EGO56322.1 - 1.8e-73 246.0 0.0 2.3e-73 245.7 0.0 1.1 1 0 0 1 1 1 1 Calcipressin DUF2236 PF09995.4 EGO56323.1 - 8.9e-32 110.2 0.8 6.8e-31 107.4 0.5 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Neugrin PF06413.6 EGO56324.1 - 2.3e-12 47.2 1.0 2.3e-12 47.2 0.7 2.3 1 1 1 2 2 2 1 Neugrin MRP-L20 PF12824.2 EGO56324.1 - 0.00045 20.2 8.9 0.00045 20.2 6.2 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 C2 PF00168.25 EGO56327.1 - 1.2e-20 73.0 0.0 3.6e-14 52.3 0.0 2.5 2 0 0 2 2 2 2 C2 domain tRNA-synt_2d PF01409.15 EGO56328.1 - 6e-46 156.6 0.3 1.3e-23 83.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EGO56328.1 - 6.7e-27 93.4 0.0 1.4e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.22 EGO56329.1 - 9.3e-58 191.9 1.5 2.1e-19 69.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_A_bac PF01000.21 EGO56330.1 - 1.7e-33 115.1 0.0 2.5e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EGO56330.1 - 6e-14 50.9 0.0 7.7e-14 50.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GrpE PF01025.14 EGO56331.1 - 5.6e-52 175.6 7.2 7.1e-52 175.2 5.0 1.1 1 0 0 1 1 1 1 GrpE Med21 PF11221.3 EGO56331.1 - 0.098 12.6 1.3 0.18 11.8 0.9 1.4 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Bap31 PF05529.7 EGO56331.1 - 3.5 7.0 8.0 0.46 9.9 2.0 1.9 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Glyco_hydro_15 PF00723.16 EGO56333.1 - 2.6e-107 359.1 0.7 3.2e-107 358.8 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EGO56333.1 - 1.1e-32 111.4 0.6 2.6e-32 110.2 0.4 1.7 1 0 0 1 1 1 1 Starch binding domain SART-1 PF03343.8 EGO56334.1 - 7.2e-168 559.7 61.2 7.2e-168 559.7 42.4 1.5 2 0 0 2 2 2 1 SART-1 family Glypican PF01153.14 EGO56334.1 - 4.3 5.8 9.6 0.14 10.7 2.0 1.9 2 0 0 2 2 2 0 Glypican DUF4066 PF13278.1 EGO56336.1 - 5.4e-22 77.8 0.0 2.4e-20 72.4 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 EGO56336.1 - 5.7e-13 48.5 0.0 8.1e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Chromo PF00385.19 EGO56337.1 - 5.3e-12 45.2 2.7 1.8e-11 43.5 1.9 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ras PF00071.17 EGO56339.1 - 4.4e-63 211.4 0.3 5.2e-63 211.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO56339.1 - 2.5e-21 76.3 0.1 4.4e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO56339.1 - 7e-13 48.1 0.1 9e-13 47.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGO56339.1 - 1.4e-07 31.4 0.1 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO56339.1 - 4.6e-06 26.1 0.1 1.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGO56339.1 - 0.00028 20.0 0.1 0.00049 19.3 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EGO56339.1 - 0.00036 20.6 0.0 0.001 19.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EGO56339.1 - 0.0011 18.1 0.0 0.0016 17.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EGO56339.1 - 0.0027 16.9 0.0 0.0061 15.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EGO56339.1 - 0.0031 17.4 0.1 0.0081 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EGO56339.1 - 0.015 14.5 0.0 0.032 13.4 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EGO56339.1 - 0.022 15.0 0.2 0.029 14.6 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EGO56339.1 - 0.027 14.4 0.2 0.05 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 EGO56339.1 - 0.031 13.8 0.1 0.05 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EGO56339.1 - 0.039 13.2 0.2 0.12 11.6 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B SpoIIID PF12116.3 EGO56339.1 - 0.041 13.8 0.1 0.56 10.1 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D AAA_29 PF13555.1 EGO56339.1 - 0.098 12.1 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EGO56339.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Brix PF04427.13 EGO56340.1 - 1.7e-40 138.6 0.0 2.3e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Brix domain DUF4110 PF13422.1 EGO56340.1 - 1.7 8.5 7.6 2.2 8.1 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4110) Hist_deacetyl PF00850.14 EGO56341.1 - 1.3e-88 297.3 0.0 1.8e-88 296.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EGO56341.1 - 7.2e-48 162.3 0.5 1.1e-47 161.7 0.3 1.3 1 0 0 1 1 1 1 Arb2 domain Gp_dh_C PF02800.15 EGO56343.1 - 1.2e-74 248.9 0.1 1.8e-74 248.4 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EGO56343.1 - 2.9e-61 205.8 0.1 5.2e-61 205.0 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EGO56343.1 - 0.0019 17.7 0.3 0.01 15.4 0.1 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase DapB_N PF01113.15 EGO56343.1 - 0.0049 16.7 0.1 0.018 14.9 0.1 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EGO56343.1 - 0.076 12.1 0.2 0.9 8.6 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pox_Ag35 PF03286.9 EGO56346.1 - 0.037 13.5 0.3 0.037 13.5 0.2 2.8 3 0 0 3 3 3 0 Pox virus Ag35 surface protein TetR_C_6 PF13977.1 EGO56347.1 - 0.061 13.3 0.8 0.11 12.4 0.5 1.4 1 0 0 1 1 1 0 Bacterial transcriptional repressor Sorting_nexin PF03700.8 EGO56347.1 - 0.15 12.1 8.9 0.61 10.1 0.4 3.0 1 1 1 2 2 2 0 Sorting nexin, N-terminal domain LRR19-TM PF15176.1 EGO56347.1 - 1.4 8.6 3.6 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain PAPA-1 PF04795.7 EGO56349.1 - 2.8e-27 95.2 1.8 2.8e-27 95.2 1.2 4.1 3 1 1 4 4 4 1 PAPA-1-like conserved region BSP_II PF05432.6 EGO56349.1 - 0.32 10.2 67.5 0.26 10.5 33.2 3.4 1 1 1 2 2 2 0 Bone sialoprotein II (BSP-II) Pex14_N PF04695.8 EGO56351.1 - 1.4e-17 63.9 1.0 1.4e-17 63.9 0.7 3.4 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region GAS PF13851.1 EGO56351.1 - 0.036 13.2 0.4 0.036 13.2 0.3 2.4 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding EURL PF06937.6 EGO56351.1 - 1.8 7.8 7.6 0.23 10.8 0.3 2.2 2 0 0 2 2 2 0 EURL protein Spore_coat_CotO PF14153.1 EGO56351.1 - 9 5.6 11.3 4.2 6.7 3.9 2.2 2 0 0 2 2 2 0 Spore coat protein CotO DUF4050 PF13259.1 EGO56352.1 - 1.3e-32 112.2 0.0 1.3e-32 112.2 0.0 3.8 3 1 0 3 3 3 1 Protein of unknown function (DUF4050) Vps39_1 PF10366.4 EGO56353.1 - 4.5e-34 116.7 0.0 1.4e-32 111.8 0.0 3.2 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EGO56353.1 - 3.2e-27 94.8 0.0 1e-26 93.2 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EGO56353.1 - 6.7e-21 74.9 0.0 1.2e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 EGO56353.1 - 2.4e-05 23.9 2.6 0.00023 20.7 0.3 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.23 EGO56353.1 - 0.0012 18.3 2.0 1.1 9.0 0.5 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO56353.1 - 0.0015 18.7 0.2 5.4 7.4 0.0 3.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGO56353.1 - 0.014 15.2 0.6 42 4.4 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EGO56353.1 - 0.015 15.4 1.1 89 3.3 0.1 4.0 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EGO56353.1 - 0.14 11.8 3.3 4.2 7.0 0.3 3.8 4 1 0 4 4 4 0 TPR repeat SPX PF03105.14 EGO56354.1 - 1.3e-50 172.6 0.4 4.5e-50 170.9 0.2 1.7 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EGO56354.1 - 1.5e-34 119.7 35.6 2.1e-34 119.2 24.7 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EGO56354.1 - 7.2e-14 51.1 44.2 1.2e-10 40.5 14.4 3.1 1 1 2 3 3 3 3 Citrate transporter ATPase_gene1 PF09527.5 EGO56354.1 - 0.0056 16.4 2.8 0.0056 16.4 1.9 3.5 3 0 0 3 3 3 1 Putative F0F1-ATPase subunit (ATPase_gene1) DUF3154 PF11351.3 EGO56354.1 - 0.082 12.6 0.3 0.082 12.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) YajC PF02699.10 EGO56354.1 - 0.18 11.5 1.0 0.87 9.2 0.7 2.2 1 0 0 1 1 1 0 Preprotein translocase subunit Gon7 PF08738.5 EGO56355.1 - 2.2e-22 78.9 6.6 3.2e-22 78.4 4.6 1.2 1 0 0 1 1 1 1 Gon7 family SSP160 PF06933.6 EGO56355.1 - 7.1 4.4 13.5 7.5 4.3 9.4 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HbrB PF08539.6 EGO56356.1 - 5.8e-59 198.4 0.0 9.3e-59 197.7 0.0 1.3 1 0 0 1 1 1 1 HbrB-like Pox_A30L_A26L PF06086.7 EGO56356.1 - 0.56 9.6 0.0 0.96 8.8 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein LIM_bind PF01803.11 EGO56359.1 - 1.8e-79 266.2 0.0 1.8e-79 266.2 0.0 4.9 3 1 2 5 5 5 1 LIM-domain binding protein Atg8 PF02991.11 EGO56360.1 - 2.6e-51 171.8 0.2 3.1e-51 171.6 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EGO56360.1 - 2.7e-06 27.4 0.0 3.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.13 EGO56361.1 - 1.5e-132 440.5 0.1 1.8e-132 440.3 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SDA1 PF05285.7 EGO56362.1 - 0.084 12.1 15.5 0.2 10.8 10.7 1.6 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 EGO56362.1 - 1.3 6.9 9.2 1.9 6.4 6.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SWIM PF04434.12 EGO56362.1 - 1.4 8.5 4.7 2.5 7.6 0.1 2.3 2 0 0 2 2 2 0 SWIM zinc finger Med12-LCEWAV PF12145.3 EGO56362.1 - 3.3 6.1 7.8 5.2 5.4 5.4 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Nop14 PF04147.7 EGO56362.1 - 3.3 5.4 18.0 5.6 4.7 12.5 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EGO56362.1 - 4.3 5.7 15.4 9.3 4.5 10.7 1.5 1 0 0 1 1 1 0 Daxx Family OAD_gamma PF04277.8 EGO56362.1 - 9.2 6.7 8.5 14 6.1 1.1 3.0 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain MitMem_reg PF13012.1 EGO56363.1 - 2.6e-39 133.8 0.2 5.8e-39 132.7 0.1 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EGO56363.1 - 5.7e-29 100.1 0.0 1.3e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DARPP-32 PF05395.7 EGO56363.1 - 0.04 14.0 3.4 0.087 12.9 2.3 1.6 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Inhibitor_I9 PF05922.11 EGO56364.1 - 2e-06 28.2 0.3 2.7e-06 27.8 0.2 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3487 PF11990.3 EGO56364.1 - 0.055 12.8 0.0 0.067 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) ADK PF00406.17 EGO56365.1 - 4.4e-59 198.6 0.0 5.7e-59 198.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EGO56365.1 - 8.5e-15 54.1 0.1 2.4e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EGO56365.1 - 9e-06 26.5 0.0 1.7e-05 25.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO56365.1 - 5.4e-05 23.0 0.0 0.00011 22.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGO56365.1 - 0.002 17.2 0.1 0.0036 16.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EGO56365.1 - 0.023 15.0 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EGO56365.1 - 0.1 11.9 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Thymidylate kinase Ribosom_S12_S23 PF00164.20 EGO56367.1 - 6.7e-41 138.5 0.5 8e-41 138.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UbiA PF01040.13 EGO56368.1 - 7.5e-32 110.5 20.7 1e-31 110.1 14.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family JmjC PF02373.17 EGO56369.1 - 5.5e-11 42.7 0.1 2.8e-10 40.4 0.1 2.3 2 1 0 2 2 2 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EGO56369.1 - 1.9e-06 27.9 8.0 1.9e-06 27.9 5.5 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EGO56369.1 - 0.051 13.0 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 Cupin domain DUF4452 PF14618.1 EGO56374.1 - 7.8e-78 259.9 8.4 9.4e-78 259.7 5.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) BTB PF00651.26 EGO56375.1 - 0.0003 20.7 0.0 0.0007 19.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF737 PF05300.6 EGO56375.1 - 9 6.2 24.9 2.9 7.8 3.7 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF737) BAF1_ABF1 PF04684.8 EGO56375.1 - 9.7 4.9 28.1 6.6 5.4 1.7 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor TauD PF02668.11 EGO56376.1 - 9.6e-45 153.2 0.0 1.1e-44 153.0 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EGO56376.1 - 0.029 14.8 0.7 0.38 11.2 0.5 2.3 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Cyclin_N PF00134.18 EGO56377.1 - 1.8e-11 43.6 0.1 6.3e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Mito_carr PF00153.22 EGO56378.1 - 6.1e-67 221.3 3.5 1.6e-24 85.3 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EGO56378.1 - 2e-21 75.9 5.4 1.2e-11 44.5 1.4 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EGO56378.1 - 6e-21 72.0 6.9 7.2e-06 24.9 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EGO56378.1 - 2.3e-16 58.1 5.6 0.00012 21.6 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGO56378.1 - 2.4e-15 55.1 11.6 5.2e-05 22.4 0.7 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EGO56378.1 - 6.2e-14 51.3 7.2 1.8e-05 24.2 0.7 3.5 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGO56378.1 - 1.5e-06 28.2 0.3 3.2e-05 23.9 0.1 2.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EGO56378.1 - 0.00084 19.0 3.0 0.31 10.7 0.2 3.2 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EGO56378.1 - 0.0041 16.7 0.2 4.2 7.1 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 EGO56378.1 - 0.03 14.2 0.1 0.8 9.6 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain DUF4098 PF13345.1 EGO56380.1 - 0.15 12.0 19.5 17 5.4 4.0 5.8 6 1 0 6 6 6 0 Domain of unknown function (DUF4098) Mito_carr PF00153.22 EGO56383.1 - 4.4e-46 154.5 6.1 3.8e-15 55.3 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3337 PF11816.3 EGO56384.1 - 1.9e-96 323.3 0.0 3.2e-94 316.0 0.6 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EGO56384.1 - 9.9e-30 101.3 10.4 3.2e-07 29.9 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EGO56384.1 - 0.014 13.5 1.2 0.034 12.2 0.2 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 ATP_bind_3 PF01171.15 EGO56385.1 - 5.2e-39 133.6 0.0 1.8e-26 92.7 0.0 2.3 2 0 0 2 2 2 2 PP-loop family Asn_synthase PF00733.16 EGO56385.1 - 9.3e-05 22.0 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase PPTA PF01239.17 EGO56386.1 - 4.5e-36 120.7 14.4 1.9e-08 33.3 0.0 5.6 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF3682 PF12446.3 EGO56386.1 - 9.2 6.5 17.2 0.58 10.4 7.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) WD40 PF00400.27 EGO56387.1 - 1.6e-09 37.2 5.6 1.8e-05 24.4 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat p450 PF00067.17 EGO56388.1 - 3.2e-07 29.2 0.5 7.5e-07 28.0 0.4 1.5 1 0 0 1 1 1 1 Cytochrome P450 FA_desaturase PF00487.19 EGO56388.1 - 0.34 10.2 1.8 2.8 7.3 1.2 2.3 3 0 0 3 3 3 0 Fatty acid desaturase SNARE PF05739.14 EGO56390.1 - 1.7e-12 46.8 5.2 3e-12 46.0 2.7 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EGO56390.1 - 0.0086 16.2 1.5 0.32 11.1 0.0 2.5 2 0 0 2 2 2 1 Syntaxin WXG100 PF06013.7 EGO56390.1 - 0.0089 16.0 3.5 0.82 9.7 0.0 3.6 2 2 0 3 3 3 1 Proteins of 100 residues with WXG Use1 PF09753.4 EGO56390.1 - 0.029 13.8 0.5 0.091 12.1 0.3 1.9 1 1 1 2 2 2 0 Membrane fusion protein Use1 Hemerythrin PF01814.18 EGO56390.1 - 0.22 11.6 7.3 0.28 11.3 0.1 2.9 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain FliJ PF02050.11 EGO56390.1 - 0.3 11.1 10.0 0.71 9.9 1.6 3.0 2 1 1 3 3 3 0 Flagellar FliJ protein Allexi_40kDa PF05549.6 EGO56390.1 - 1.3 8.2 5.6 0.5 9.6 1.7 1.8 2 0 0 2 2 2 0 Allexivirus 40kDa protein Viral_P18 PF04521.8 EGO56390.1 - 4.9 6.6 5.1 1.4 8.3 0.1 2.4 2 1 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein TPR_MLP1_2 PF07926.7 EGO56390.1 - 7.6 6.2 9.7 0.5 10.1 0.7 2.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3716 PF12511.3 EGO56391.1 - 2.3e-17 62.3 2.1 3.6e-17 61.7 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF3245 PF11595.3 EGO56391.1 - 0.85 9.8 5.1 1.5 9.0 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) DUF4559 PF15112.1 EGO56393.1 - 0.25 10.4 2.2 0.26 10.4 1.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Tfb4 PF03850.9 EGO56394.1 - 1.1e-85 287.2 0.9 4.4e-60 203.2 0.0 2.1 2 0 0 2 2 2 2 Transcription factor Tfb4 XRCC4 PF06632.7 EGO56395.1 - 2.2e-07 30.0 5.9 2.2e-07 30.0 4.1 2.2 1 1 1 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 V_ATPase_I PF01496.14 EGO56395.1 - 0.96 7.2 3.3 1.4 6.7 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ACCA PF03255.9 EGO56395.1 - 1.6 8.3 5.0 1.9 8.0 0.9 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ACP_syn_III PF08545.5 EGO56396.1 - 0.085 12.5 0.0 0.086 12.5 0.0 1.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2648 PF10855.3 EGO56396.1 - 0.15 11.4 0.1 0.26 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) Cofilin_ADF PF00241.15 EGO56398.1 - 1.6e-32 112.0 0.6 1.9e-32 111.8 0.4 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cpn60_TCP1 PF00118.19 EGO56399.1 - 5.1e-118 394.7 7.7 5.9e-118 394.5 5.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HET PF06985.6 EGO56401.1 - 3.3e-35 121.2 2.0 1.7e-34 118.9 0.3 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EGO56402.1 - 3.9e-31 108.0 0.5 6.6e-31 107.3 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Antimicrobial12 PF08107.6 EGO56403.1 - 0.032 13.7 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Pleurocidin family WD40 PF00400.27 EGO56404.1 - 8.7e-35 117.3 5.6 1.8e-08 33.8 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 EGO56404.1 - 3.6e-32 110.2 16.2 6.3e-32 109.4 11.3 1.4 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 EGO56404.1 - 2.4e-06 27.2 0.2 1.4 8.6 0.0 5.2 3 2 3 6 6 6 2 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 EGO56404.1 - 0.00041 20.0 1.4 0.0006 19.5 0.1 1.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGO56404.1 - 0.0061 14.8 0.1 0.015 13.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain DUF2246 PF10229.4 EGO56404.1 - 0.0098 15.2 0.4 0.016 14.5 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2246) DUF2361 PF10153.4 EGO56404.1 - 0.25 11.5 12.8 0.38 10.9 8.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) PCI PF01399.22 EGO56405.1 - 1.8e-20 73.2 0.8 6.1e-20 71.5 0.1 2.3 3 0 0 3 3 3 1 PCI domain TPR_8 PF13181.1 EGO56405.1 - 3.4e-05 23.3 2.0 4.4 7.3 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat DDRGK PF09756.4 EGO56405.1 - 0.00035 20.0 0.2 0.0007 19.0 0.1 1.5 1 0 0 1 1 1 1 DDRGK domain TPR_7 PF13176.1 EGO56405.1 - 0.002 17.8 6.6 0.26 11.1 0.2 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF627 PF04781.7 EGO56405.1 - 0.0094 15.5 0.6 0.42 10.2 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF627) Med2 PF11214.3 EGO56405.1 - 0.012 15.5 0.5 0.073 13.1 0.1 2.5 2 0 0 2 2 2 0 Mediator complex subunit 2 TPR_16 PF13432.1 EGO56405.1 - 0.021 15.4 12.3 1.6 9.4 0.7 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EGO56405.1 - 0.072 12.8 0.6 0.2 11.4 0.4 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 DUF87 PF01935.12 EGO56405.1 - 0.15 11.8 1.7 0.48 10.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 TPR_12 PF13424.1 EGO56405.1 - 0.45 10.4 17.9 0.22 11.4 0.3 5.3 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGO56405.1 - 0.51 10.9 0.1 0.51 10.9 0.1 2.7 3 0 0 3 3 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGO56405.1 - 1.7 9.4 14.4 17 6.3 0.1 6.4 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGO56405.1 - 3.6 7.3 8.9 8.5 6.1 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGO56405.1 - 5.8 7.0 14.9 7.4 6.7 0.0 5.4 6 1 0 6 6 4 0 Tetratricopeptide repeat Sds3 PF08598.6 EGO56408.1 - 1e-54 185.2 5.5 1.5e-54 184.6 3.8 1.4 1 1 0 1 1 1 1 Sds3-like LSM PF01423.17 EGO56409.1 - 6.5e-15 54.4 0.1 3.7e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 LSM domain Mob1_phocein PF03637.12 EGO56412.1 - 1.8e-69 232.9 0.0 2.2e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.13 EGO56413.1 - 1.7e-45 154.9 0.9 2.3e-45 154.5 0.6 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit PepSY_TM_2 PF13703.1 EGO56414.1 - 0.031 14.4 0.9 0.06 13.5 0.6 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix His_Phos_2 PF00328.17 EGO56415.1 - 6.9e-05 22.3 0.0 0.00058 19.3 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Carn_acyltransf PF00755.15 EGO56416.1 - 5.9e-170 566.2 0.0 2.3e-154 514.7 0.0 2.0 1 1 0 2 2 2 2 Choline/Carnitine o-acyltransferase OB_NTP_bind PF07717.11 EGO56417.1 - 1.9e-27 95.3 0.2 1e-26 92.9 0.1 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGO56417.1 - 3.5e-23 81.5 0.0 8.6e-23 80.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGO56417.1 - 6.1e-12 45.2 0.0 1.3e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO56417.1 - 6e-08 32.3 0.2 1.7e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGO56417.1 - 1.1e-07 32.1 0.0 2.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EGO56417.1 - 0.0002 20.8 0.1 0.00054 19.4 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 EGO56417.1 - 0.0023 16.8 0.0 0.0047 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 EGO56417.1 - 0.0042 16.9 0.0 0.82 9.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EGO56417.1 - 0.012 14.4 0.0 0.05 12.4 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 EGO56417.1 - 0.017 15.2 0.5 0.21 11.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EGO56417.1 - 0.039 13.5 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Response_reg PF00072.19 EGO56417.1 - 0.073 13.0 0.2 0.9 9.5 0.0 2.4 2 0 0 2 2 2 0 Response regulator receiver domain AAA_16 PF13191.1 EGO56417.1 - 0.09 12.7 0.0 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain PhoH PF02562.11 EGO56417.1 - 0.1 11.8 0.0 0.45 9.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 EGO56417.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EGO56417.1 - 0.13 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRMT5 PF05185.11 EGO56418.1 - 1.7e-168 561.2 0.0 2.1e-168 560.9 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase DUF1772 PF08592.6 EGO56418.1 - 0.16 11.6 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) LSM PF01423.17 EGO56419.1 - 3.4e-20 71.3 0.2 4e-20 71.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF2435 PF10363.4 EGO56420.1 - 1.4e-14 53.7 0.1 1.1e-12 47.6 0.0 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EGO56420.1 - 1.7e-13 49.6 2.3 3.1e-13 48.8 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2411) T2SF PF00482.18 EGO56420.1 - 0.062 13.2 0.7 6.5 6.6 0.1 3.0 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F 14-3-3 PF00244.15 EGO56420.1 - 0.063 12.3 0.2 0.76 8.8 0.0 2.2 2 0 0 2 2 2 0 14-3-3 protein MIF4G PF02854.14 EGO56420.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 MIF4G domain STAT_bind PF02864.10 EGO56426.1 - 0.11 12.1 0.4 0.2 11.2 0.3 1.3 1 0 0 1 1 1 0 STAT protein, DNA binding domain DUF1227 PF06777.6 EGO56428.1 - 6.3e-60 201.1 0.1 6.3e-60 201.1 0.1 2.1 2 0 0 2 2 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EGO56428.1 - 8.1e-52 175.1 0.5 1.5e-51 174.2 0.4 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EGO56428.1 - 1.6e-44 151.7 0.1 5.4e-44 150.0 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain SNF2_N PF00176.18 EGO56428.1 - 2.5e-05 23.2 0.0 9.3e-05 21.3 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EGO56428.1 - 0.0012 18.3 0.0 0.52 9.7 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 EGO56428.1 - 0.0067 16.2 3.2 0.013 15.3 0.1 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EGO56428.1 - 0.015 14.8 0.1 0.015 14.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EGO56428.1 - 0.023 14.4 0.0 0.076 12.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 EGO56428.1 - 0.035 13.3 0.2 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Radial_spoke_3 PF06098.6 EGO56428.1 - 0.51 9.3 13.6 0.95 8.4 9.4 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 U1snRNP70_N PF12220.3 EGO56428.1 - 2.7 8.3 6.8 0.3 11.4 1.3 2.0 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal zf-C2H2 PF00096.21 EGO56431.1 - 5.4e-14 51.5 16.7 0.00014 21.9 0.7 3.9 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO56431.1 - 1.2e-10 40.9 14.9 0.00049 20.2 0.2 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGO56431.1 - 1.5e-05 24.9 21.1 9.8e-05 22.4 1.3 4.2 4 1 1 5 5 5 2 Zinc-finger double domain zf-C2HC_2 PF13913.1 EGO56431.1 - 0.023 14.3 0.5 0.065 12.9 0.3 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-TRAF PF02176.13 EGO56431.1 - 0.15 12.4 9.0 0.71 10.2 1.1 2.6 1 1 2 3 3 3 0 TRAF-type zinc finger zf-BED PF02892.10 EGO56431.1 - 0.21 11.3 9.8 1.1 9.0 2.9 2.9 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.2 EGO56431.1 - 0.21 11.7 4.3 0.4 10.8 1.9 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EGO56431.1 - 0.26 11.2 4.5 0.3 11.0 1.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger EPSP_synthase PF00275.15 EGO56434.1 - 2.2e-129 431.6 0.0 5.1e-129 430.3 0.0 1.6 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EGO56434.1 - 1.5e-100 335.4 0.0 2.7e-100 334.5 0.0 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EGO56434.1 - 2.5e-65 220.3 0.0 4.1e-65 219.5 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EGO56434.1 - 1.9e-38 131.7 0.0 9.8e-37 126.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EGO56434.1 - 7.1e-25 86.8 0.0 1.7e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EGO56434.1 - 1e-12 48.3 0.0 3.7e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EGO56434.1 - 3.5e-09 36.3 0.0 8.8e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EGO56434.1 - 6.4e-05 23.7 0.0 0.00017 22.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGO56434.1 - 0.0098 15.0 0.0 0.074 12.1 0.0 2.4 3 0 0 3 3 3 1 Zeta toxin AAA_14 PF13173.1 EGO56434.1 - 0.26 11.2 0.0 0.92 9.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sugar_tr PF00083.19 EGO56435.1 - 6.6e-128 427.0 22.3 7.5e-128 426.9 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO56435.1 - 8.5e-19 67.4 39.5 1.1e-15 57.2 15.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGO56435.1 - 0.27 11.0 0.1 0.27 11.0 0.0 4.7 4 2 1 5 5 5 0 MFS_1 like family UPF0197 PF05251.7 EGO56435.1 - 7.8 6.8 8.5 0.43 10.9 0.2 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0197) Histone PF00125.19 EGO56436.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EGO56436.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EGO56436.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGO56436.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGO56436.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EGO56436.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EGO56437.1 - 3.6e-31 107.0 0.4 5.8e-31 106.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGO56437.1 - 4.1e-06 26.8 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGO56437.1 - 0.004 17.1 0.3 0.0074 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGO56437.1 - 0.014 15.1 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DSBA PF01323.15 EGO56438.1 - 1.7e-19 70.1 0.0 1.9e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain PRP3 PF08572.5 EGO56439.1 - 2.3e-73 246.2 8.0 3.8e-73 245.5 5.5 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EGO56439.1 - 1.6e-42 144.1 1.1 4e-42 142.9 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.12 EGO56440.1 - 2.3e-88 296.0 0.0 5.1e-88 294.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EGO56440.1 - 5e-64 215.2 0.2 1.2e-63 214.0 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EGO56440.1 - 5.8e-32 110.6 0.0 1.5e-31 109.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EGO56440.1 - 3.3e-30 105.5 1.0 1.2e-20 74.0 0.0 3.1 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EGO56440.1 - 1.4e-18 66.6 7.4 2e-18 66.0 0.1 3.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 zf-C2H2 PF00096.21 EGO56442.1 - 1.1e-09 38.0 11.8 0.0072 16.6 0.8 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO56442.1 - 6.4e-07 29.2 16.0 0.0033 17.6 0.9 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.7 EGO56442.1 - 1.7 8.8 6.9 0.66 10.1 0.8 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EGO56442.1 - 3.7 8.0 10.9 2.5 8.5 0.3 4.4 5 0 0 5 5 5 0 Zinc-finger double domain RasGAP PF00616.14 EGO56443.1 - 1.1e-44 152.4 0.0 2.2e-44 151.5 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EGO56443.1 - 2.8e-07 30.5 0.1 7.3e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HEAT PF02985.17 EGO56443.1 - 0.04 14.0 1.9 2.5 8.3 0.1 4.4 4 0 0 4 4 4 0 HEAT repeat XRN_N PF03159.13 EGO56444.1 - 3e-110 367.2 0.0 3.6e-110 366.9 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_3 PF13917.1 EGO56444.1 - 0.051 13.3 0.2 0.098 12.4 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Uso1_p115_head PF04869.9 EGO56445.1 - 6.8e-119 396.2 0.3 1.8e-118 394.8 0.0 2.0 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EGO56445.1 - 3.1e-33 114.5 34.9 3.1e-33 114.5 24.2 5.6 2 1 3 5 5 5 1 Uso1 / p115 like vesicle tethering protein, C terminal region KfrA_N PF11740.3 EGO56445.1 - 0.002 18.5 10.0 0.002 18.5 6.9 8.7 2 2 6 9 9 9 1 Plasmid replication region DNA-binding N-term NUC130_3NT PF08158.7 EGO56445.1 - 0.013 15.7 0.1 0.073 13.3 0.0 2.3 1 0 0 1 1 1 0 NUC130/3NT domain HEAT PF02985.17 EGO56445.1 - 0.014 15.4 0.5 2.2 8.5 0.1 3.4 2 0 0 2 2 2 0 HEAT repeat WW PF00397.21 EGO56446.1 - 1.9e-07 30.7 7.5 4e-07 29.7 5.2 1.6 1 0 0 1 1 1 1 WW domain Choline_transpo PF04515.7 EGO56448.1 - 4.8e-09 35.4 21.2 4.8e-09 35.4 14.7 3.2 3 1 0 3 3 3 2 Plasma-membrane choline transporter Ras PF00071.17 EGO56449.1 - 5.7e-50 168.8 0.0 1.3e-38 131.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EGO56449.1 - 2.4e-16 60.2 0.1 9.8e-15 55.0 0.0 2.3 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO56449.1 - 4.9e-12 45.4 0.0 5.8e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGO56449.1 - 1.9e-07 30.7 0.0 3.3e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGO56449.1 - 9.6e-07 28.1 0.0 5.8e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGO56449.1 - 5.7e-05 23.0 0.0 0.00017 21.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGO56449.1 - 0.024 14.7 0.0 0.45 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EGO56449.1 - 0.043 13.2 0.1 3.9 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EGO56449.1 - 0.12 11.8 0.1 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EGO56449.1 - 0.13 12.2 1.2 0.39 10.6 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EGO56449.1 - 0.15 12.3 0.4 0.35 11.1 0.3 2.0 1 1 0 1 1 1 0 ABC transporter DUF3439 PF11921.3 EGO56449.1 - 0.19 11.4 4.9 0.34 10.6 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF605 PF04652.11 EGO56449.1 - 0.84 8.9 8.4 1.4 8.2 5.8 1.3 1 0 0 1 1 1 0 Vta1 like PMT PF02366.13 EGO56450.1 - 1.8e-80 269.8 20.6 1.8e-80 269.8 14.3 2.3 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EGO56450.1 - 4.2e-39 134.0 2.1 5.6e-39 133.6 1.5 1.2 1 0 0 1 1 1 1 MIR domain DUF3712 PF12505.3 EGO56451.1 - 9.6e-06 25.6 0.0 2.1e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) L51_S25_CI-B8 PF05047.11 EGO56453.1 - 6.5e-25 86.6 0.1 1.1e-24 85.8 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MMR_HSR1 PF01926.18 EGO56454.1 - 3e-06 27.1 0.0 1.3e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Phage_F PF02305.12 EGO56454.1 - 0.059 11.8 0.1 0.092 11.2 0.1 1.1 1 0 0 1 1 1 0 Capsid protein (F protein) Cys_Met_Meta_PP PF01053.15 EGO56455.1 - 7e-140 465.6 0.0 8e-140 465.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGO56455.1 - 3.7e-11 42.6 0.2 1.1e-10 41.1 0.1 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EGO56455.1 - 1.1e-08 34.1 0.2 1.8e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGO56455.1 - 3.1e-07 29.6 0.0 4.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.11 EGO56455.1 - 0.00084 18.1 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EGO56455.1 - 0.0012 18.1 0.0 0.0017 17.5 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 EGO56455.1 - 0.0039 15.5 0.1 0.0057 15.0 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase MARVEL PF01284.18 EGO56456.1 - 4.1e-14 52.5 14.9 6e-14 52.0 10.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DPM3 PF08285.6 EGO56456.1 - 0.065 13.0 1.2 0.12 12.2 0.8 1.5 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PIG-Y PF15159.1 EGO56456.1 - 0.5 10.6 3.9 1 9.6 0.1 2.9 2 1 1 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y AMP-binding PF00501.23 EGO56457.1 - 1.4e-74 250.9 0.0 1.8e-74 250.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2012 PF09430.5 EGO56458.1 - 5e-22 78.0 0.0 7.1e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) WD40 PF00400.27 EGO56459.1 - 0.19 11.6 23.2 0.5 10.3 0.1 6.5 8 0 0 8 8 8 0 WD domain, G-beta repeat CtaG_Cox11 PF04442.9 EGO56460.1 - 3.1e-56 189.3 0.4 8.4e-56 187.9 0.0 1.8 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 FNIP_N PF14636.1 EGO56460.1 - 6.3e-05 23.4 2.9 0.0001 22.7 2.0 1.2 1 0 0 1 1 1 1 Folliculin-interacting protein N-terminus Rav1p_C PF12234.3 EGO56461.1 - 2e-283 941.3 0.0 2.4e-283 941.0 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 EGO56461.1 - 3.8e-06 26.5 0.4 7.3 6.6 0.0 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat UIM PF02809.15 EGO56461.1 - 0.76 9.5 2.2 11 5.9 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin interaction motif OPT PF03169.10 EGO56462.1 - 2.7e-151 505.1 15.4 3e-151 504.9 10.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4212 PF13937.1 EGO56462.1 - 0.017 15.1 5.6 0.096 12.7 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) DENN PF02141.16 EGO56463.1 - 1.9e-58 197.2 0.0 3.1e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EGO56463.1 - 1.7e-18 66.3 0.0 3.4e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EGO56463.1 - 6.3e-18 64.6 0.1 1.2e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 dDENN domain C1_1 PF00130.17 EGO56463.1 - 0.04 13.6 8.0 0.075 12.7 5.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 EGO56463.1 - 0.38 10.4 7.9 0.87 9.3 5.4 1.7 1 0 0 1 1 1 0 PHD-finger DUF974 PF06159.8 EGO56465.1 - 1.1e-88 296.9 0.0 1.3e-88 296.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) KH_1 PF00013.24 EGO56466.1 - 2.5e-12 46.2 0.0 8.2e-09 34.9 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EGO56466.1 - 1.9e-07 30.5 0.7 2.7e-05 23.6 0.1 3.0 3 0 0 3 3 3 2 KH domain ALS_ss_C PF10369.4 EGO56467.1 - 2.8e-18 65.4 0.0 4e-17 61.7 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EGO56467.1 - 6.5e-12 44.6 0.1 1.2e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EGO56467.1 - 8.4e-10 38.3 0.0 1.5e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 ACT domain OTCace_N PF02729.16 EGO56468.1 - 9.9e-41 138.7 0.0 1.6e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EGO56468.1 - 8.1e-39 133.0 0.0 1.4e-38 132.2 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Gp_dh_N PF00044.19 EGO56468.1 - 0.019 14.8 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF3712 PF12505.3 EGO56469.1 - 0.00034 20.6 0.0 2.2 8.3 0.0 3.9 4 1 0 4 4 4 2 Protein of unknown function (DUF3712) PrmA PF06325.8 EGO56470.1 - 1e-11 44.5 1.4 1.3e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EGO56470.1 - 4.7e-11 42.4 0.0 1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO56470.1 - 2.1e-10 41.1 0.5 1.1e-09 38.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO56470.1 - 3.1e-09 36.8 0.1 1.5e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO56470.1 - 6.6e-09 36.1 0.0 1.7e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO56470.1 - 1.3e-07 31.1 0.1 2.3e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EGO56470.1 - 9.3e-07 28.6 0.0 1.8e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO56470.1 - 3e-05 24.3 0.0 7.3e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGO56470.1 - 9.8e-05 21.9 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 EGO56470.1 - 0.00015 21.2 0.2 0.00036 20.0 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.7 EGO56470.1 - 0.00033 21.0 0.0 0.00073 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGO56470.1 - 0.00073 19.1 0.1 0.0012 18.4 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.15 EGO56470.1 - 0.0053 15.8 0.0 0.0085 15.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EGO56470.1 - 0.007 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 EGO56470.1 - 0.017 13.8 0.0 0.032 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.9 EGO56470.1 - 0.026 13.7 0.2 0.057 12.5 0.2 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB UPF0020 PF01170.13 EGO56470.1 - 0.048 13.2 0.1 0.099 12.2 0.1 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 EGO56470.1 - 0.072 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF3294 PF07957.6 EGO56470.1 - 0.082 12.4 0.5 0.14 11.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Methyltransf_4 PF02390.12 EGO56470.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PPI_Ypi1 PF07491.6 EGO56471.1 - 2.3e-22 78.3 8.4 1.4e-21 75.8 5.9 2.2 1 1 0 1 1 1 1 Protein phosphatase inhibitor Cwf_Cwc_15 PF04889.7 EGO56471.1 - 0.17 11.5 3.2 0.28 10.8 2.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MTBP_C PF14920.1 EGO56471.1 - 1.2 8.5 6.2 1.4 8.3 4.3 1.2 1 0 0 1 1 1 0 MDM2-binding CDC45 PF02724.9 EGO56471.1 - 3 5.7 7.2 3.7 5.4 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF726 PF05277.7 EGO56472.1 - 2.5e-136 454.1 0.1 3.8e-136 453.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF605 PF04652.11 EGO56473.1 - 4.3 6.6 12.7 5.8 6.2 8.8 1.1 1 0 0 1 1 1 0 Vta1 like SNAP PF14938.1 EGO56474.1 - 1.6e-103 345.7 21.8 1.8e-103 345.5 15.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EGO56474.1 - 7.5e-05 22.5 8.1 0.042 13.7 0.2 3.2 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGO56474.1 - 0.0048 16.7 13.5 2.6 8.1 0.2 6.1 5 1 3 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGO56474.1 - 0.057 13.0 14.1 2.2 7.9 4.2 4.1 2 1 2 4 4 4 0 TPR repeat Spatacsin_C PF14649.1 EGO56474.1 - 0.13 11.1 9.4 2.8 6.7 0.5 3.0 1 1 0 3 3 3 0 Spatacsin C-terminus DUF2225 PF09986.4 EGO56474.1 - 1.7 8.0 9.8 1.2 8.5 1.3 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) NUC173 PF08161.7 EGO56475.1 - 4.5e-82 274.2 0.3 2.4e-77 258.7 0.0 3.9 4 0 0 4 4 4 2 NUC173 domain HEAT PF02985.17 EGO56475.1 - 0.002 18.0 0.9 3.5 7.9 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EGO56475.1 - 0.012 15.9 9.9 0.052 13.8 0.6 4.8 5 0 0 5 5 5 0 HEAT repeats TFCD_C PF12612.3 EGO56475.1 - 0.41 10.0 6.7 4.3 6.7 0.0 4.6 3 1 1 4 4 4 0 Tubulin folding cofactor D C terminal Amino_oxidase PF01593.19 EGO56476.1 - 1.6e-13 50.6 0.2 3.3e-11 42.9 0.0 2.9 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGO56476.1 - 2.8e-12 46.4 0.0 7.8e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGO56476.1 - 1.6e-07 31.2 0.0 0.013 15.3 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EGO56476.1 - 1.4e-05 25.2 0.0 0.0069 16.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO56476.1 - 2.3e-05 23.4 0.0 7.6e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGO56476.1 - 0.0024 18.2 0.0 0.018 15.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EGO56476.1 - 0.034 13.7 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 EGO56476.1 - 0.041 13.7 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO56476.1 - 0.13 10.6 0.0 6.8 5.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein DUF4462 PF14692.1 EGO56476.1 - 1.5 8.1 5.2 0.26 10.5 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) E1-E2_ATPase PF00122.15 EGO56478.1 - 1.3e-64 217.3 7.1 2.8e-64 216.3 4.9 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGO56478.1 - 6.3e-21 75.7 0.0 1.4e-20 74.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGO56478.1 - 1.5e-11 44.8 0.0 4.4e-11 43.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGO56478.1 - 5.2e-10 38.6 0.0 1.2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGO56478.1 - 0.0044 16.6 0.1 0.008 15.7 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO56478.1 - 0.0095 15.8 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF1010 PF06231.6 EGO56479.1 - 0.11 12.4 0.3 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) DUF3628 PF12300.3 EGO56481.1 - 0.041 13.9 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Adipokin_hormo PF06377.6 EGO56481.1 - 0.16 12.0 4.0 1.6 8.9 2.7 2.2 1 1 0 1 1 1 0 Adipokinetic hormone Uroplakin_II PF07353.7 EGO56482.1 - 0.15 11.4 0.2 0.15 11.3 0.1 1.1 1 0 0 1 1 1 0 Uroplakin II PepSY_TM_3 PF13706.1 EGO56483.1 - 0.045 13.1 1.8 0.11 11.9 1.3 1.7 1 0 0 1 1 1 0 PepSY-associated TM helix Mito_carr PF00153.22 EGO56485.1 - 3.9e-30 103.4 6.3 5.1e-13 48.5 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.16 EGO56487.1 - 1.6e-104 349.5 0.0 2e-104 349.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EGO56487.1 - 0.011 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone XH PF03469.9 EGO56487.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 XH domain RRM_5 PF13893.1 EGO56488.1 - 1e-07 31.6 0.1 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO56488.1 - 1e-06 28.2 0.0 1.8e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO56488.1 - 1.6e-05 24.7 0.0 3.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EGO56488.1 - 0.0022 18.2 0.0 0.007 16.5 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. CTD_bind PF04818.8 EGO56489.1 - 0.0057 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRN7 PF11781.3 EGO56489.1 - 0.026 14.0 3.7 0.34 10.4 0.7 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_4 PF13894.1 EGO56489.1 - 0.48 10.8 1.8 7 7.2 0.3 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EGO56489.1 - 2.4 7.9 5.4 2.4 7.9 0.6 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type 4F5 PF04419.9 EGO56491.1 - 5.8e-10 39.7 13.5 5.8e-10 39.7 9.3 2.3 2 0 0 2 2 2 1 4F5 protein family HpaB_N PF11794.3 EGO56491.1 - 0.088 12.1 0.6 0.089 12.1 0.4 1.0 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Cu_bind_like PF02298.12 EGO56492.1 - 0.016 14.9 0.2 0.14 12.0 0.1 2.2 1 1 0 1 1 1 0 Plastocyanin-like domain DUF912 PF06024.7 EGO56492.1 - 1.5 8.9 3.3 2.9 7.9 2.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SMN PF06003.7 EGO56493.1 - 1.8e-08 33.8 0.3 6.5e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Survival motor neuron protein (SMN) FGGY_C PF02782.11 EGO56494.1 - 1.5e-50 171.5 0.4 2.2e-50 171.0 0.3 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGO56494.1 - 1.1e-21 77.3 0.4 4.4e-19 68.7 0.0 2.8 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.16 EGO56494.1 - 0.0014 18.0 0.0 0.025 13.8 0.0 2.2 2 0 0 2 2 2 1 Hexokinase BcrAD_BadFG PF01869.15 EGO56494.1 - 0.0038 16.5 0.0 0.024 13.9 0.0 2.2 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family Nic96 PF04097.9 EGO56495.1 - 4.6e-218 725.2 0.0 5.4e-218 725.0 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 EGO56495.1 - 3.6e-17 62.6 167.4 1e-09 38.6 36.7 4.0 2 1 2 4 4 4 3 Nucleoporin FG repeat region Aldo_ket_red PF00248.16 EGO56496.1 - 3e-17 62.3 0.0 1.2e-16 60.3 0.0 1.9 2 1 0 2 2 2 1 Aldo/keto reductase family GFO_IDH_MocA PF01408.17 EGO56497.1 - 3.7e-21 75.8 0.4 7.4e-21 74.8 0.3 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EGO56497.1 - 0.0078 16.5 0.2 0.013 15.8 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.12 EGO56497.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain VirK PF06903.7 EGO56497.1 - 0.12 12.0 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 VirK protein Methyltransf_11 PF08241.7 EGO56498.1 - 2.4e-12 47.1 0.5 1.3e-11 44.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO56498.1 - 3.6e-09 36.5 0.0 8.2e-09 35.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO56498.1 - 1.9e-07 31.3 0.4 5.9e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO56498.1 - 2.7e-06 27.0 0.0 4.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO56498.1 - 3.6e-06 27.3 0.0 3.6e-06 27.3 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain Hamartin PF04388.7 EGO56498.1 - 0.00016 20.5 2.4 0.00027 19.7 1.6 1.4 1 0 0 1 1 1 1 Hamartin protein Methyltransf_18 PF12847.2 EGO56498.1 - 0.00092 19.7 0.3 0.0062 17.1 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO56498.1 - 0.0011 18.9 0.1 0.004 17.1 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO56498.1 - 0.058 12.5 0.0 0.18 10.8 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family AAA_25 PF13481.1 EGO56498.1 - 0.073 12.4 0.6 0.16 11.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain RIC3 PF15361.1 EGO56498.1 - 0.4 10.9 7.5 0.79 9.9 5.2 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Myb_DNA-binding PF00249.26 EGO56499.1 - 7.5e-12 45.1 2.0 8.3e-09 35.3 0.0 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGO56499.1 - 3.5e-07 30.2 2.5 0.00018 21.5 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain CAP_GLY PF01302.20 EGO56506.1 - 4.3e-23 80.8 1.9 6.2e-23 80.2 1.3 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EGO56506.1 - 3.6e-18 65.6 0.0 5.4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EGO56506.1 - 0.00016 20.9 0.0 0.00057 19.2 0.0 1.9 1 1 1 2 2 2 1 Ubiquitin family zf-RING_2 PF13639.1 EGO56509.1 - 1.6e-13 50.2 4.6 2.6e-13 49.5 3.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGO56509.1 - 1e-06 28.2 3.0 1.6e-06 27.6 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGO56509.1 - 2.8e-06 27.3 0.9 5e-06 26.5 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGO56509.1 - 5.7e-06 26.2 5.2 9.2e-06 25.5 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO56509.1 - 2.3e-05 24.0 1.5 3.6e-05 23.4 1.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGO56509.1 - 7.3e-05 22.3 1.5 0.00013 21.5 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGO56509.1 - 0.012 15.4 1.0 0.024 14.4 0.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGO56509.1 - 0.015 14.8 2.7 0.027 14.0 1.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H PF13771.1 EGO56509.1 - 0.049 13.7 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 EGO56509.1 - 0.26 11.0 3.0 0.41 10.4 0.7 1.9 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 EGO56509.1 - 0.64 10.0 4.1 22 5.0 2.7 3.2 2 1 0 2 2 2 0 FANCL C-terminal domain Glyco_hydro_cc PF11790.3 EGO56512.1 - 3.1e-59 200.2 3.0 4.6e-59 199.7 0.6 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core SOG2 PF10428.4 EGO56512.1 - 3.5 6.1 10.6 5.4 5.5 7.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ank PF00023.25 EGO56513.1 - 2.3e-14 52.3 2.3 1.5e-09 37.1 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EGO56513.1 - 7.3e-14 51.8 0.1 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGO56513.1 - 4.9e-13 48.8 1.5 5.3e-12 45.5 0.3 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TIG PF01833.19 EGO56513.1 - 4e-10 39.5 0.6 4e-10 39.5 0.4 2.1 2 0 0 2 2 2 1 IPT/TIG domain Ank_3 PF13606.1 EGO56513.1 - 2.7e-08 33.2 0.4 4.8e-05 23.2 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EGO56513.1 - 1.9e-06 28.1 0.1 7e-06 26.4 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Na_H_Exchanger PF00999.16 EGO56515.1 - 1e-38 132.9 17.7 1.4e-38 132.4 12.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MnhB PF04039.8 EGO56515.1 - 0.022 14.8 1.0 0.022 14.8 0.7 3.0 4 1 0 4 4 4 0 Domain related to MnhB subunit of Na+/H+ antiporter DUF981 PF06168.6 EGO56515.1 - 1.5 8.5 11.3 0.029 14.1 1.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF981) dCMP_cyt_deam_1 PF00383.17 EGO56516.1 - 1.3e-10 40.8 0.2 2.8e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region 6PF2K PF01591.13 EGO56518.1 - 9.6e-65 217.7 0.0 6.9e-45 152.8 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGO56518.1 - 1.1e-27 97.0 0.1 7.2e-27 94.4 0.0 2.2 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EGO56518.1 - 4.1e-06 26.7 0.2 5.3e-05 23.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGO56518.1 - 0.023 15.4 0.1 0.11 13.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.5 EGO56518.1 - 0.057 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CARD PF00619.16 EGO56518.1 - 0.078 12.8 0.2 0.25 11.2 0.1 1.9 1 1 0 1 1 1 0 Caspase recruitment domain UPF0262 PF06793.7 EGO56518.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) RusA PF05866.6 EGO56519.1 - 0.084 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA Velvet PF11754.3 EGO56523.1 - 2e-63 213.6 0.0 3.1e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Velvet factor LHH PF14411.1 EGO56524.1 - 2.6 8.2 6.8 20 5.4 0.1 2.2 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Bac_rhodopsin PF01036.13 EGO56525.1 - 1e-36 126.3 25.9 1.3e-36 125.9 18.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Methuselah_N PF06652.7 EGO56526.1 - 0.071 12.6 0.9 0.087 12.3 0.6 1.1 1 0 0 1 1 1 0 Methuselah N-terminus Arm PF00514.18 EGO56528.1 - 1.1e-12 47.2 9.4 9.8e-05 22.0 0.0 8.2 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGO56528.1 - 6.4e-06 26.3 3.2 0.73 10.1 0.0 5.3 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EGO56528.1 - 1.2e-05 24.9 3.2 4.5 7.6 0.0 6.8 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 EGO56528.1 - 0.0037 17.7 3.9 13 6.4 0.0 5.5 4 0 0 4 4 4 1 HEAT-like repeat V-ATPase_H_C PF11698.3 EGO56528.1 - 0.13 12.1 0.2 0.58 10.0 0.0 2.2 2 0 0 2 2 2 0 V-ATPase subunit H Cyclin PF08613.6 EGO56529.1 - 1.2e-30 106.8 0.1 2.6e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EGO56529.1 - 2.3e-05 23.9 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cohesin PF00963.13 EGO56530.1 - 0.058 13.2 1.0 0.1 12.4 0.7 1.3 1 0 0 1 1 1 0 Cohesin domain UPF0370 PF13980.1 EGO56530.1 - 0.21 11.4 1.0 0.35 10.6 0.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) CHZ PF09649.5 EGO56531.1 - 1.1e-17 62.9 0.5 1.1e-17 62.9 0.3 3.1 4 0 0 4 4 4 1 Histone chaperone domain CHZ BSP_II PF05432.6 EGO56531.1 - 2.2 7.4 25.1 3.1 7.0 17.4 1.3 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) SNARE PF05739.14 EGO56532.1 - 4.6e-09 35.8 4.4 6.2e-09 35.4 3.0 1.2 1 0 0 1 1 1 1 SNARE domain GRP PF07172.6 EGO56532.1 - 0.051 14.0 11.7 0.088 13.2 8.1 1.5 1 0 0 1 1 1 0 Glycine rich protein family Chorion_3 PF05387.6 EGO56532.1 - 0.48 9.8 3.0 0.53 9.6 2.1 1.2 1 0 0 1 1 1 0 Chorion family 3 Apc15p PF05841.6 EGO56533.1 - 2.8e-28 99.1 3.6 2.8e-28 99.1 2.5 3.0 3 0 0 3 3 3 1 Apc15p protein Glu_synthase PF01645.12 EGO56536.1 - 1.1e-157 524.6 0.0 1.6e-157 524.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EGO56536.1 - 1.1e-141 471.7 0.0 1.5e-141 471.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EGO56536.1 - 3.8e-118 393.9 0.0 7.2e-118 393.0 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EGO56536.1 - 1.8e-68 229.5 1.9 3.3e-68 228.6 1.3 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EGO56536.1 - 8.9e-23 80.0 0.1 2.4e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EGO56536.1 - 4.3e-17 62.6 0.0 1.6e-16 60.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO56536.1 - 1.2e-09 38.5 0.5 8.6e-05 22.6 0.1 2.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO56536.1 - 5.7e-09 35.8 0.4 1.6e-08 34.4 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGO56536.1 - 1.2e-07 32.0 0.2 4.3e-05 23.8 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EGO56536.1 - 1.9e-06 27.2 0.1 3e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EGO56536.1 - 2.7e-05 23.2 0.2 9.7e-05 21.4 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO56536.1 - 2.9e-05 23.1 0.1 0.0001 21.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EGO56536.1 - 3.3e-05 22.5 0.2 3.3e-05 22.5 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.1 EGO56536.1 - 8.2e-05 22.8 0.6 0.1 12.8 0.1 3.0 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 EGO56536.1 - 0.00025 20.2 0.0 0.00049 19.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGO56536.1 - 0.00048 19.2 0.1 0.0037 16.3 0.1 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EGO56536.1 - 0.00085 18.4 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.14 EGO56536.1 - 0.00096 17.4 0.2 0.42 8.7 0.0 2.8 2 1 0 3 3 3 2 Flavin-binding monooxygenase-like AlaDh_PNT_C PF01262.16 EGO56536.1 - 0.0011 18.5 0.1 0.0079 15.7 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EGO56536.1 - 0.0025 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DJ-1_PfpI PF01965.19 EGO56536.1 - 0.0071 15.8 0.4 2.2 7.7 0.0 2.5 1 1 1 2 2 2 1 DJ-1/PfpI family GIDA PF01134.17 EGO56536.1 - 0.013 14.3 1.1 0.053 12.3 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 EGO56536.1 - 0.022 14.8 0.3 11 6.1 0.0 3.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 EGO56536.1 - 0.061 12.7 0.1 0.17 11.2 0.1 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 EGO56536.1 - 0.074 12.4 0.2 0.4 10.1 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 EGO56536.1 - 0.079 12.7 0.0 0.28 10.9 0.0 2.0 1 0 0 1 1 1 0 FAD-NAD(P)-binding VTC PF09359.5 EGO56537.1 - 5.3e-97 324.2 1.9 9.3e-97 323.4 1.3 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EGO56537.1 - 1.6e-17 64.2 27.4 7.7e-16 58.6 12.2 3.9 3 1 0 3 3 3 1 SPX domain DUF202 PF02656.10 EGO56537.1 - 7.1e-09 35.7 3.9 7.1e-09 35.7 2.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4600 PF15372.1 EGO56537.1 - 0.0076 16.4 2.1 0.019 15.1 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) Lebercilin PF15619.1 EGO56537.1 - 0.015 14.7 2.9 0.038 13.4 2.0 1.6 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease TBPIP PF07106.8 EGO56537.1 - 0.031 13.8 2.2 0.065 12.7 1.5 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Colicin_V PF02674.11 EGO56537.1 - 0.32 10.8 6.0 0.57 10.0 4.1 1.3 1 0 0 1 1 1 0 Colicin V production protein bZIP_2 PF07716.10 EGO56537.1 - 0.37 10.6 8.7 0.73 9.7 0.9 2.7 2 0 0 2 2 2 0 Basic region leucine zipper Ctf8 PF09696.5 EGO56538.1 - 2.9e-19 69.0 0.0 3.7e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Ctf8 GDPD PF03009.12 EGO56539.1 - 1.5e-43 149.1 0.0 2.1e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family WW PF00397.21 EGO56540.1 - 4.5e-08 32.8 0.8 9.9e-08 31.7 0.5 1.6 1 0 0 1 1 1 1 WW domain ABC_membrane_2 PF06472.10 EGO56541.1 - 1.3e-109 365.6 2.4 1.3e-109 365.6 1.7 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EGO56541.1 - 1.8e-17 63.9 0.0 9.5e-17 61.5 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EGO56541.1 - 0.00065 19.7 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO56541.1 - 0.022 14.7 0.5 0.094 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain RuvB_N PF05496.7 EGO56541.1 - 0.036 13.1 0.0 0.15 11.0 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 EGO56541.1 - 0.039 13.4 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 EGO56541.1 - 0.09 11.9 0.0 0.25 10.5 0.0 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGO56541.1 - 0.09 13.0 0.2 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EGO56541.1 - 0.1 11.7 0.2 0.49 9.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 EGO56541.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 G_glu_transpept PF01019.16 EGO56545.1 - 4.1e-170 566.6 0.0 4.7e-170 566.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase GIT_SHD PF08518.6 EGO56545.1 - 0.21 10.9 0.1 0.42 10.0 0.1 1.5 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT ADH_N PF08240.7 EGO56546.1 - 3.5e-30 103.9 0.7 6.2e-30 103.1 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO56546.1 - 3.3e-27 94.5 0.2 7.2e-27 93.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO56546.1 - 2.8e-07 31.4 0.1 5.1e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2226 PF09987.4 EGO56546.1 - 0.074 12.1 0.1 0.1 11.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) Actin PF00022.14 EGO56547.1 - 8.8e-90 300.9 0.0 1.9e-89 299.8 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGO56547.1 - 0.06 11.9 0.0 2.4 6.6 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.13 EGO56548.1 - 2.8e-36 124.8 0.8 4.3e-20 71.6 0.0 2.2 2 0 0 2 2 2 2 Asparaginase HTH_31 PF13560.1 EGO56548.1 - 0.066 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain UPF0061 PF02696.9 EGO56549.1 - 4e-120 401.4 0.0 4.9e-120 401.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family BORA_N PF15280.1 EGO56549.1 - 0.0081 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein aurora borealis N-terminus Aldo_ket_red PF00248.16 EGO56550.1 - 1.9e-48 164.7 0.0 2.4e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PUF PF00806.14 EGO56551.1 - 7e-39 129.1 0.4 2.8e-06 26.4 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat ATG16 PF08614.6 EGO56551.1 - 0.43 10.3 3.4 0.83 9.4 2.0 1.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MRP-S33 PF08293.6 EGO56552.1 - 2.3e-20 72.3 0.0 3.3e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 RRP14 PF15459.1 EGO56552.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Ribonuclease_3 PF00636.21 EGO56553.1 - 1.2e-14 54.7 0.0 5.7e-14 52.5 0.0 2.1 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGO56553.1 - 7.5e-14 51.7 0.0 6.2e-13 48.8 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.20 EGO56553.1 - 0.021 15.3 0.0 0.021 15.3 0.0 2.5 2 0 0 2 2 2 0 Double-stranded RNA binding motif BRF1 PF07741.8 EGO56553.1 - 2.8 8.1 6.9 29 4.9 4.7 2.3 1 1 0 1 1 1 0 Brf1-like TBP-binding domain ACBP PF00887.14 EGO56554.1 - 4.5e-30 103.1 0.0 7.9e-30 102.3 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein RCR PF12273.3 EGO56554.1 - 0.49 10.9 9.8 0.54 10.8 0.5 2.5 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Molybdopterin PF00384.17 EGO56556.1 - 1.3e-78 264.6 0.0 1.2e-76 258.2 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 EGO56556.1 - 2.1e-19 69.1 0.1 5.2e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 EGO56556.1 - 1.4e-18 65.8 0.1 4.6e-18 64.1 0.1 2.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EGO56556.1 - 9.7e-15 54.4 0.0 2.4e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EGO56556.1 - 2.3e-09 36.8 0.5 2.3e-09 36.8 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EGO56556.1 - 0.0079 15.9 0.0 0.33 10.7 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain PP2C PF00481.16 EGO56558.1 - 4.1e-43 147.6 0.0 6.9e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EGO56558.1 - 0.00011 21.9 0.1 0.27 10.9 0.0 3.4 4 0 0 4 4 4 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EGO56558.1 - 0.0011 18.4 0.0 0.003 16.9 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C ComK PF06338.6 EGO56558.1 - 0.039 13.3 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 ComK protein Glyco_hydro_63 PF03200.11 EGO56559.1 - 1.7e-08 32.8 2.7 1.1e-06 26.7 1.9 3.1 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Podoplanin PF05808.6 EGO56560.1 - 0.00044 19.8 1.4 0.00068 19.2 1.0 1.2 1 0 0 1 1 1 1 Podoplanin DUF202 PF02656.10 EGO56560.1 - 0.0037 17.4 0.0 0.008 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DUF1191 PF06697.7 EGO56560.1 - 0.006 15.4 0.0 0.0087 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Herpes_gE PF02480.11 EGO56560.1 - 0.018 13.3 0.0 0.029 12.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 EGO56560.1 - 0.09 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RNA_pol_Rpb2_6 PF00562.23 EGO56562.1 - 1.5e-115 386.0 0.1 2.1e-115 385.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGO56562.1 - 1e-46 158.4 0.0 1.7e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EGO56562.1 - 7.9e-31 106.9 0.0 3e-30 105.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EGO56562.1 - 3.8e-30 103.9 0.3 9e-30 102.7 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EGO56562.1 - 3.7e-20 71.5 1.6 4.1e-20 71.3 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EGO56562.1 - 1.2e-19 69.7 0.0 2.4e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EGO56562.1 - 1.4e-11 44.1 0.3 4.8e-11 42.4 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 DUF342 PF03961.8 EGO56563.1 - 0.035 12.5 0.9 0.046 12.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Clathrin_lg_ch PF01086.12 EGO56563.1 - 0.25 11.2 3.9 0.065 13.1 0.7 1.5 2 0 0 2 2 2 0 Clathrin light chain PUF PF00806.14 EGO56564.1 - 1.6e-65 213.0 11.7 3.2e-08 32.6 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat TylF PF05711.6 EGO56564.1 - 0.025 13.6 0.1 0.044 12.8 0.1 1.3 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Ribosomal_L15e PF00827.12 EGO56565.1 - 1.4e-91 305.2 12.0 1.6e-91 305.0 8.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 SpaB_C PF14028.1 EGO56566.1 - 0.049 13.1 0.2 0.078 12.5 0.1 1.5 1 1 0 1 1 1 0 SpaB C-terminal domain Exonuc_VII_S PF02609.11 EGO56566.1 - 0.054 13.2 0.3 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Exonuclease VII small subunit PSP1 PF04468.7 EGO56567.1 - 6.2e-31 106.2 0.7 1.1e-30 105.4 0.5 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Rotavirus_VP3 PF06929.6 EGO56567.1 - 0.33 8.7 0.4 0.49 8.2 0.3 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein Nfu_N PF08712.6 EGO56570.1 - 1.4e-30 104.7 0.1 3.6e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EGO56570.1 - 3.1e-22 78.1 0.1 6.1e-22 77.1 0.1 1.5 1 0 0 1 1 1 1 NifU-like domain zf-HIT PF04438.11 EGO56571.1 - 6.3e-10 38.5 9.3 9.4e-10 37.9 6.4 1.3 1 0 0 1 1 1 1 HIT zinc finger Spore_coat_CotO PF14153.1 EGO56571.1 - 4.8e-06 26.1 15.5 4.8e-06 26.1 10.8 2.6 3 0 0 3 3 3 1 Spore coat protein CotO Ycf1 PF05758.7 EGO56571.1 - 1.2e-05 23.2 5.4 1.2e-05 23.2 3.8 1.3 2 0 0 2 2 2 1 Ycf1 zf-MYND PF01753.13 EGO56571.1 - 6.2e-05 22.7 7.6 0.00015 21.5 5.2 1.6 1 0 0 1 1 1 1 MYND finger DUF605 PF04652.11 EGO56571.1 - 0.0028 17.1 50.0 0.0041 16.5 34.7 1.1 1 0 0 1 1 1 1 Vta1 like PAT1 PF09770.4 EGO56571.1 - 0.038 12.2 70.8 0.053 11.7 49.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Otopetrin PF03189.8 EGO56571.1 - 0.28 10.1 2.3 0.39 9.6 1.6 1.3 1 0 0 1 1 1 0 Otopetrin LMBR1 PF04791.11 EGO56571.1 - 0.45 9.0 3.1 0.6 8.6 2.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6 PF04111.7 EGO56571.1 - 2.2 7.2 22.7 3.9 6.4 15.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Bud13 PF09736.4 EGO56571.1 - 5.9 7.1 33.4 0.12 12.6 17.5 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Gti1_Pac2 PF09729.4 EGO56571.1 - 5.9 6.7 15.7 1.3 8.9 7.8 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family Anoctamin PF04547.7 EGO56571.1 - 7 5.1 9.4 10 4.6 6.5 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel Serinc PF03348.10 EGO56571.1 - 8.1 5.0 18.3 14 4.2 12.7 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1266 PF06889.6 EGO56571.1 - 8.5 6.1 14.5 23 4.7 8.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) RasGEF PF00617.14 EGO56573.1 - 3.4e-42 144.2 0.2 5.3e-42 143.6 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain Miro PF08477.8 EGO56573.1 - 4.8e-24 85.1 0.0 1.6e-23 83.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein RasGEF_N PF00618.15 EGO56573.1 - 6.4e-14 51.9 0.0 1.3e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.17 EGO56573.1 - 3.2e-05 23.3 0.0 0.0004 19.8 0.0 2.5 2 1 0 2 2 2 1 Ras family FtsK_SpoIIIE PF01580.13 EGO56573.1 - 0.014 14.9 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EGO56573.1 - 0.12 12.5 0.0 0.99 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 EGO56573.1 - 0.21 10.3 0.0 0.37 9.5 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PIG-H PF10181.4 EGO56574.1 - 1.1e-26 92.2 0.1 1.6e-26 91.7 0.1 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.15 EGO56575.1 - 2.8e-28 98.4 0.0 9.2e-23 80.6 0.0 2.9 2 1 0 2 2 2 2 tRNA pseudouridine synthase Ras PF00071.17 EGO56576.1 - 5e-16 58.5 0.0 1.6e-13 50.3 0.0 2.2 1 1 1 2 2 2 2 Ras family Miro PF08477.8 EGO56576.1 - 0.00013 22.4 0.0 0.59 10.6 0.0 2.2 1 1 0 2 2 2 2 Miro-like protein Arf PF00025.16 EGO56576.1 - 0.0047 16.1 0.0 0.098 11.8 0.0 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family RNA_pol_Rpb4 PF03874.11 EGO56577.1 - 3.5e-23 81.8 2.6 4.2e-23 81.5 1.8 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Glyco_transf_54 PF04666.8 EGO56577.1 - 0.071 11.8 0.7 0.085 11.5 0.5 1.2 1 1 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Pribosyl_synth PF14572.1 EGO56578.1 - 3.3e-38 131.2 1.0 3e-33 115.1 0.3 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EGO56578.1 - 7.1e-29 99.9 0.0 1.9e-28 98.5 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EGO56578.1 - 1e-11 44.6 0.1 2.2e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGO56578.1 - 0.0022 17.2 0.1 0.004 16.3 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase SLAC1 PF03595.12 EGO56579.1 - 1.1e-54 185.2 35.1 7.7e-51 172.6 19.8 2.1 1 1 1 2 2 2 2 Voltage-dependent anion channel DUF4593 PF15263.1 EGO56579.1 - 0.056 13.3 5.7 0.035 13.9 2.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4593) DUF202 PF02656.10 EGO56579.1 - 3.3 8.0 17.0 12 6.2 0.9 4.5 2 1 2 4 4 4 0 Domain of unknown function (DUF202) CCT_2 PF09425.5 EGO56582.1 - 0.063 12.8 0.2 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Divergent CCT motif Radial_spoke_3 PF06098.6 EGO56583.1 - 0.2 10.6 4.1 0.26 10.2 2.8 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 Snf7 PF03357.16 EGO56585.1 - 8.7e-23 80.5 9.7 8.7e-23 80.5 6.7 1.8 1 1 1 2 2 2 1 Snf7 TPR_MLP1_2 PF07926.7 EGO56585.1 - 3.4 7.4 8.5 6.4 6.5 5.9 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3484 PF11983.3 EGO56585.1 - 7.4 7.4 7.9 6.5 7.6 1.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3484) CS PF04969.11 EGO56586.1 - 7.1e-08 32.8 0.0 1.1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 CS domain RRM_1 PF00076.17 EGO56588.1 - 2.1e-16 59.3 0.0 3.5e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO56588.1 - 2.1e-13 50.0 0.0 3.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO56588.1 - 1.2e-06 28.2 0.0 2.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EGO56588.1 - 0.0013 19.1 0.2 0.0013 19.1 0.1 3.0 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Gly-rich_Ago1 PF12764.2 EGO56588.1 - 0.04 14.5 2.4 0.04 14.5 1.7 2.5 2 1 0 2 2 2 0 Glycine-rich region of argonaut Smg4_UPF3 PF03467.10 EGO56588.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family Ost4 PF10215.4 EGO56589.1 - 1.4e-17 62.9 0.4 2.1e-17 62.3 0.3 1.3 1 0 0 1 1 1 1 Oligosaccaryltransferase Afaf PF15339.1 EGO56589.1 - 0.0049 16.5 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 Acrosome formation-associated factor zf-CCCH PF00642.19 EGO56590.1 - 1.6e-05 24.4 0.9 1.6e-05 24.4 0.6 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AT_hook PF02178.14 EGO56591.1 - 3.5 7.6 14.8 7.5 6.5 3.6 3.3 2 0 0 2 2 2 0 AT hook motif zf-C2H2_4 PF13894.1 EGO56591.1 - 3.9 8.0 5.1 2.1 8.8 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Ribosomal_60s PF00428.14 EGO56591.1 - 5.9 7.3 9.0 19 5.7 4.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pkinase PF00069.20 EGO56592.1 - 8.3e-71 238.1 0.0 1.6e-70 237.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO56592.1 - 4.4e-30 104.6 0.0 1.1e-28 99.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO56592.1 - 1.2e-06 27.7 0.0 0.42 9.5 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.9 EGO56592.1 - 0.017 14.1 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO56592.1 - 0.026 14.2 0.0 1.3 8.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DASH_Dad3 PF08656.5 EGO56594.1 - 8.3e-28 95.9 0.3 9.6e-28 95.6 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 PilJ PF13675.1 EGO56594.1 - 0.057 13.7 0.2 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term CK2S PF15011.1 EGO56594.1 - 0.067 12.9 0.1 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate Ribosomal_S5_C PF03719.10 EGO56595.1 - 3e-19 68.0 0.1 1.8e-18 65.5 0.0 2.3 3 0 0 3 3 3 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EGO56595.1 - 1.4e-10 40.7 0.2 2.7e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain PgaD PF13994.1 EGO56596.1 - 0.0033 16.9 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 PgaD-like protein DUF2763 PF10961.3 EGO56596.1 - 0.06 13.7 0.0 0.075 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) TLC PF03219.9 EGO56596.1 - 0.072 11.5 0.0 0.082 11.3 0.0 1.0 1 0 0 1 1 1 0 TLC ATP/ADP transporter DUF3609 PF12259.3 EGO56596.1 - 0.092 11.3 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) UPF0542 PF15086.1 EGO56596.1 - 0.12 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 ATE_C PF04377.10 EGO56598.1 - 4.9e-42 142.9 0.1 8.2e-42 142.2 0.0 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EGO56598.1 - 3.9e-16 58.6 1.2 8.3e-16 57.5 0.4 1.8 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus NUDIX PF00293.23 EGO56599.1 - 1.8e-18 66.4 0.7 2.1e-18 66.2 0.5 1.1 1 0 0 1 1 1 1 NUDIX domain COG5 PF10392.4 EGO56600.1 - 0.016 15.1 2.6 0.03 14.2 0.3 2.4 2 1 0 2 2 2 0 Golgi transport complex subunit 5 RNase_PH PF01138.16 EGO56601.1 - 6.2e-15 55.6 0.0 1.3e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGO56601.1 - 0.0083 16.0 0.1 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cytochrom_C PF00034.16 EGO56603.1 - 5.2e-10 40.0 0.1 7.6e-10 39.5 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EGO56603.1 - 1.2e-08 34.9 2.8 5.4e-08 32.8 2.0 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EGO56603.1 - 0.00098 18.5 0.3 0.0079 15.6 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.9 EGO56603.1 - 0.042 14.1 0.0 0.085 13.1 0.0 1.6 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase AAA PF00004.24 EGO56604.1 - 6.1e-86 285.3 0.0 2.1e-46 157.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGO56604.1 - 6.6e-15 54.8 0.0 7.3e-08 31.7 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EGO56604.1 - 2.3e-10 40.3 1.4 3.4e-05 23.5 0.0 4.1 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGO56604.1 - 2.4e-10 40.7 11.9 7.8e-05 22.7 0.0 4.7 3 2 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 EGO56604.1 - 2.8e-10 40.4 1.2 0.0049 17.0 0.0 4.8 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EGO56604.1 - 2.4e-09 37.1 0.0 0.00044 20.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EGO56604.1 - 9.1e-09 35.2 0.0 0.0042 16.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EGO56604.1 - 1.9e-08 34.4 0.0 0.00023 21.1 0.0 3.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EGO56604.1 - 2.8e-08 34.5 1.4 0.0091 16.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EGO56604.1 - 1.1e-07 31.4 1.3 0.024 14.4 0.1 3.6 3 1 0 3 3 3 2 Part of AAA domain Zeta_toxin PF06414.7 EGO56604.1 - 1.3e-06 27.6 0.0 0.0039 16.3 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 EGO56604.1 - 1.8e-06 28.0 0.0 0.11 12.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 EGO56604.1 - 2.7e-06 27.7 1.2 0.032 14.5 0.0 3.2 3 1 0 3 3 2 2 ABC transporter IstB_IS21 PF01695.12 EGO56604.1 - 3.8e-06 26.4 0.7 0.057 12.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.8 EGO56604.1 - 4.5e-06 25.6 0.1 0.078 11.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_28 PF13521.1 EGO56604.1 - 6.7e-06 26.1 1.9 0.089 12.7 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EGO56604.1 - 1.2e-05 25.6 2.2 0.27 11.5 0.0 3.7 4 0 0 4 4 3 2 AAA domain DUF815 PF05673.8 EGO56604.1 - 2.8e-05 23.1 0.0 0.024 13.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EGO56604.1 - 3.9e-05 23.2 0.0 0.37 10.2 0.0 2.9 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 EGO56604.1 - 4.1e-05 23.0 9.7 1.2 8.4 0.3 4.8 2 2 2 4 4 4 1 AAA domain NACHT PF05729.7 EGO56604.1 - 4.8e-05 23.0 1.4 0.079 12.6 0.1 3.7 4 0 0 4 4 3 1 NACHT domain Mg_chelatase PF01078.16 EGO56604.1 - 6.1e-05 22.2 0.7 0.09 11.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NB-ARC PF00931.17 EGO56604.1 - 0.00011 21.2 0.3 0.16 10.7 0.1 2.5 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activ_2 PF14532.1 EGO56604.1 - 0.00011 22.2 0.0 0.14 12.2 0.0 2.9 2 0 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.10 EGO56604.1 - 0.00019 20.2 0.0 0.44 9.1 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein KaiC PF06745.8 EGO56604.1 - 0.00022 20.4 0.1 1 8.4 0.0 3.0 3 0 0 3 3 3 2 KaiC ATP-synt_ab PF00006.20 EGO56604.1 - 0.0011 18.4 0.0 1.4 8.4 0.0 2.8 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_3 PF07726.6 EGO56604.1 - 0.002 17.7 0.1 1.8 8.2 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EGO56604.1 - 0.0025 17.3 0.0 0.68 9.4 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.13 EGO56604.1 - 0.0027 17.3 0.3 0.52 9.9 0.1 3.1 3 1 0 3 3 2 1 Bacterial dnaA protein AAA_24 PF13479.1 EGO56604.1 - 0.0029 17.2 0.5 4.3 6.8 0.1 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 EGO56604.1 - 0.0032 17.1 1.1 2.7 7.6 0.0 3.0 3 0 0 3 3 3 1 NTPase SKI PF01202.17 EGO56604.1 - 0.0035 17.2 3.2 0.71 9.7 0.0 3.1 3 0 0 3 3 3 1 Shikimate kinase UPF0079 PF02367.12 EGO56604.1 - 0.0043 16.6 0.1 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 EGO56604.1 - 0.0055 16.2 0.1 0.14 11.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 EGO56604.1 - 0.0096 15.4 0.0 0.62 9.5 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.11 EGO56604.1 - 0.013 14.7 1.9 1.4 8.1 0.2 2.4 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.10 EGO56604.1 - 0.029 14.1 0.0 1.7 8.4 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Vps4_C PF09336.5 EGO56604.1 - 0.035 13.9 0.1 0.21 11.5 0.1 2.4 3 0 0 3 3 1 0 Vps4 C terminal oligomerisation domain Arch_ATPase PF01637.13 EGO56604.1 - 0.07 12.8 5.8 8.5 5.9 0.0 4.0 4 2 2 6 6 5 0 Archaeal ATPase Parvo_NS1 PF01057.12 EGO56604.1 - 0.1 11.4 0.4 5 5.9 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 SRPRB PF09439.5 EGO56604.1 - 0.16 11.1 2.3 13 4.9 0.0 3.4 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 EGO56604.1 - 2.3 8.5 12.0 1.2 9.4 0.0 3.9 4 0 0 4 4 4 0 AAA domain HrpA_pilin PF09589.5 EGO56604.1 - 3.1 8.2 7.4 0.84 10.0 2.3 2.2 2 0 0 2 2 1 0 HrpA pilus formation protein Mito_carr PF00153.22 EGO56606.1 - 1.3e-45 152.9 8.8 7.1e-17 60.8 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Complex1_LYR PF05347.10 EGO56607.1 - 1.1e-07 31.5 0.3 1.9e-07 30.7 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGO56607.1 - 0.0093 16.1 0.5 0.018 15.2 0.3 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Sugar_tr PF00083.19 EGO56609.1 - 6.1e-103 344.8 15.8 7.2e-103 344.5 10.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO56609.1 - 1.8e-29 102.5 25.8 2.9e-28 98.6 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGO56609.1 - 0.00011 21.9 0.3 0.001 18.8 0.1 2.4 2 0 0 2 2 2 1 MFS_1 like family DUF791 PF05631.9 EGO56609.1 - 0.0032 16.2 2.2 0.0032 16.2 1.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF791) MFS_3 PF05977.8 EGO56609.1 - 0.58 8.1 6.3 0.4 8.7 1.2 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Chs3p PF12271.3 EGO56610.1 - 5.9e-83 278.2 9.6 7.6e-83 277.8 6.7 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF1218 PF06749.7 EGO56610.1 - 0.63 10.5 4.8 1.3 9.5 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) Cytochrom_B561 PF03188.11 EGO56611.1 - 2.2e-17 63.1 8.6 2.3e-17 63.1 5.1 1.6 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 PepSY_TM_1 PF13172.1 EGO56611.1 - 0.13 12.0 0.3 0.13 12.0 0.2 3.4 3 0 0 3 3 3 0 PepSY-associated TM helix Prion_bPrPp PF11587.3 EGO56611.1 - 0.21 11.2 2.2 2.9 7.6 0.4 2.5 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal DUF4079 PF13301.1 EGO56611.1 - 0.57 10.1 15.9 1.9 8.4 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.15 EGO56611.1 - 1.2 8.4 16.4 0.96 8.8 0.5 2.8 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Cytochrom_B_N PF00033.14 EGO56611.1 - 3.4 6.9 19.1 15 4.8 7.8 3.1 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Allantoicase PF03561.10 EGO56612.1 - 9e-113 372.6 0.1 7.2e-60 200.8 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat DIL PF01843.14 EGO56613.1 - 5.6e-19 67.9 1.1 5.2e-12 45.5 0.1 2.6 2 0 0 2 2 2 2 DIL domain Ank_2 PF12796.2 EGO56613.1 - 4.7e-18 65.3 0.1 1.5e-17 63.7 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGO56613.1 - 1.5e-16 59.2 0.0 1.3e-05 24.7 0.0 4.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EGO56613.1 - 1.5e-13 50.8 0.1 3.3e-06 27.4 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO56613.1 - 6e-12 45.3 0.0 6.4e-07 29.4 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO56613.1 - 2.1e-09 36.7 0.0 0.032 14.4 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat RabGAP-TBC PF00566.13 EGO56614.1 - 8.1e-33 113.6 0.0 1.3e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2722 PF10846.3 EGO56615.1 - 7.5e-05 21.9 0.2 7.5e-05 21.9 0.1 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF2722) CRM1_C PF08767.6 EGO56617.1 - 4.4e-132 439.8 4.7 6.4e-132 439.2 1.5 2.5 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.7 EGO56617.1 - 1.3e-40 138.7 7.0 1.3e-40 138.7 4.9 3.5 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EGO56617.1 - 1.1e-12 47.7 0.1 4.1e-12 45.8 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EGO56617.1 - 0.055 13.8 2.8 2.4 8.5 0.0 4.5 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region uDENN PF03456.13 EGO56617.1 - 0.15 12.0 0.9 7.5 6.6 0.0 3.6 4 0 0 4 4 4 0 uDENN domain DUF3385 PF11865.3 EGO56617.1 - 0.16 11.8 0.0 0.16 11.8 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Aminotran_5 PF00266.14 EGO56618.1 - 5e-29 101.1 0.0 6.7e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 EGO56618.1 - 0.058 13.2 0.1 0.51 10.2 0.0 2.3 2 0 0 2 2 2 0 B12 binding domain Pox_M2 PF04887.7 EGO56618.1 - 0.18 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus M2 protein Metallophos_2 PF12850.2 EGO56619.1 - 8.9e-15 54.8 0.0 1.2e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGO56619.1 - 0.0018 17.7 0.0 0.014 14.7 0.0 2.0 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase HATPase_c PF02518.21 EGO56620.1 - 1.4e-28 98.8 0.1 2.9e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGO56620.1 - 1.5e-20 73.2 0.1 3.8e-20 71.9 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EGO56620.1 - 1e-19 70.2 0.4 4.2e-19 68.2 0.3 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 EGO56620.1 - 4.9e-14 52.7 0.2 2.6e-13 50.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.1 EGO56620.1 - 2.1e-10 41.2 0.0 6.7e-10 39.6 0.0 2.0 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EGO56620.1 - 4.2e-10 39.2 0.2 1.3e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain GAF_3 PF13492.1 EGO56620.1 - 1.2e-08 35.1 0.0 3.2e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.12 EGO56620.1 - 1.2e-05 24.5 0.0 2.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_8 PF13181.1 EGO56620.1 - 0.00049 19.6 0.4 0.17 11.7 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat HATPase_c_3 PF13589.1 EGO56620.1 - 0.00087 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_16 PF13432.1 EGO56620.1 - 0.014 16.0 6.3 0.75 10.5 0.7 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat NACHT PF05729.7 EGO56620.1 - 0.015 14.9 0.1 0.2 11.2 0.0 2.4 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 EGO56620.1 - 0.1 11.4 0.0 0.25 10.1 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain TPR_12 PF13424.1 EGO56620.1 - 0.12 12.2 14.1 0.66 9.9 2.9 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGO56620.1 - 0.56 11.0 9.6 6.2 7.7 0.6 4.5 2 1 1 3 3 3 0 Tetratricopeptide repeat NAD_binding_8 PF13450.1 EGO56621.1 - 1.9e-09 37.4 0.1 4e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGO56621.1 - 9.7e-07 28.2 0.0 2.7e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EGO56621.1 - 7.6e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO56621.1 - 0.0074 16.1 0.0 0.04 13.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO56621.1 - 0.014 14.4 0.1 0.023 13.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EGO56621.1 - 0.05 12.0 0.1 0.075 11.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 EGO56621.1 - 0.076 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EGO56621.1 - 0.091 11.8 0.4 0.22 10.5 0.1 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EGO56621.1 - 0.13 11.1 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain TPT PF03151.11 EGO56622.1 - 1.5e-28 99.3 12.1 1.5e-28 99.3 8.4 2.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EGO56622.1 - 1.2e-06 27.7 27.0 1.1e-05 24.5 18.7 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGO56622.1 - 0.013 15.5 8.8 0.013 15.5 6.1 3.0 3 1 1 4 4 4 0 EamA-like transporter family Ribosomal_L27e PF01777.13 EGO56623.1 - 1.4e-37 127.6 3.7 1.9e-37 127.2 2.6 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EGO56623.1 - 0.011 15.3 0.2 0.04 13.6 0.1 1.9 1 0 0 1 1 1 0 KOW motif DUF1922 PF09082.5 EGO56623.1 - 0.11 12.6 0.1 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) ECM11 PF15463.1 EGO56623.1 - 0.24 11.7 1.4 0.28 11.4 0.2 1.6 2 0 0 2 2 2 0 Extracellular mutant protein 11 DUF2665 PF11654.3 EGO56624.1 - 1.4e-08 34.1 0.0 1.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) TPR_11 PF13414.1 EGO56625.1 - 0.011 15.4 0.2 5.9 6.6 0.0 2.5 1 1 1 2 2 2 0 TPR repeat Glyoxalase PF00903.20 EGO56626.1 - 9.9e-21 74.0 0.1 9e-14 51.5 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EGO56626.1 - 1.5e-13 50.7 0.1 3.2e-07 30.3 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGO56626.1 - 6.9e-10 39.5 0.0 2.4e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EGO56626.1 - 0.00056 19.8 0.0 1 9.2 0.0 3.1 3 0 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EGO56626.1 - 0.0058 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Ssl1 PF04056.9 EGO56627.1 - 6.2e-59 198.8 0.0 2.2e-35 122.0 0.0 2.2 1 1 1 2 2 2 2 Ssl1-like VWA_2 PF13519.1 EGO56627.1 - 1.7e-05 25.0 0.0 0.0012 18.9 0.0 2.2 1 1 0 2 2 2 1 von Willebrand factor type A domain DZR PF12773.2 EGO56627.1 - 1.8 8.4 8.1 20 5.0 5.6 2.4 1 1 0 1 1 1 0 Double zinc ribbon HATPase_c PF02518.21 EGO56628.1 - 8.6e-24 83.3 0.3 2e-23 82.2 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.6 EGO56628.1 - 5.9e-23 80.7 0.2 4.1e-13 49.2 0.1 3.7 3 0 0 3 3 3 3 PAS fold HisKA PF00512.20 EGO56628.1 - 8.1e-21 73.7 0.1 2e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EGO56628.1 - 1.4e-20 73.3 0.1 5.2e-20 71.5 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain PAS_9 PF13426.1 EGO56628.1 - 7.6e-18 64.8 0.0 5.3e-09 36.3 0.0 3.9 2 1 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EGO56628.1 - 1e-10 41.5 0.1 2.3e-07 30.8 0.0 3.1 3 0 0 3 3 3 2 PAS fold PAS PF00989.19 EGO56628.1 - 2.9e-08 33.4 0.0 0.013 15.2 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.1 EGO56628.1 - 0.11 12.4 0.0 15 5.5 0.0 2.6 2 0 0 2 2 2 0 PAS domain Ecl1 PF12855.2 EGO56631.1 - 6.1e-09 35.0 3.8 1e-08 34.2 2.6 1.4 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 EGO56631.1 - 0.085 12.7 2.2 0.2 11.5 1.5 1.6 1 0 0 1 1 1 0 MYND finger DUF581 PF04570.9 EGO56631.1 - 1.6 8.0 5.1 22 4.4 3.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF581) Macoilin PF09726.4 EGO56631.1 - 4.6 5.3 12.6 5.3 5.1 8.7 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF3678 PF12435.3 EGO56632.1 - 0.048 13.2 0.1 0.068 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) COesterase PF00135.23 EGO56637.1 - 1.5e-86 291.2 0.0 2.3e-86 290.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO56637.1 - 3.7e-06 26.6 0.2 1.3e-05 24.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DASH_Dad2 PF08654.5 EGO56639.1 - 2.7e-33 114.0 1.5 3.5e-33 113.6 1.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 Shugoshin_N PF07558.6 EGO56640.1 - 3.6e-15 55.3 2.4 6.9e-15 54.4 1.6 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EGO56640.1 - 9.7e-12 44.1 5.8 9.7e-12 44.1 4.0 4.5 5 0 0 5 5 5 1 Shugoshin C terminus HALZ PF02183.13 EGO56640.1 - 0.67 9.7 4.6 0.22 11.2 1.0 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cpn60_TCP1 PF00118.19 EGO56641.1 - 1e-163 545.4 0.1 1.2e-163 545.2 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 EGO56642.1 - 1.3e-41 141.4 16.0 1.3e-41 141.4 11.1 2.1 2 2 0 2 2 2 1 Protein of unknown function (DUF1168) His_Phos_1 PF00300.17 EGO56643.1 - 3.6e-33 114.9 0.0 6.3e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EGO56643.1 - 0.00043 19.7 0.0 0.00078 18.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Paf1 PF03985.8 EGO56643.1 - 3.1 6.4 6.6 4.9 5.7 4.6 1.3 1 0 0 1 1 1 0 Paf1 SKG6 PF08693.5 EGO56644.1 - 1.8e-06 27.1 6.6 1.8e-06 27.1 4.6 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 EGO56644.1 - 0.00099 18.8 8.4 0.00099 18.8 5.9 3.1 1 1 1 2 2 2 1 TMEM154 protein family DUF4448 PF14610.1 EGO56644.1 - 0.0014 18.1 0.0 0.0029 17.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) CcmD PF04995.9 EGO56644.1 - 0.0037 16.9 2.4 0.0067 16.1 1.7 1.3 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) Ank_2 PF12796.2 EGO56645.1 - 8.3e-39 131.8 6.9 9e-14 51.5 0.0 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO56645.1 - 4.6e-29 100.2 8.1 1.6e-09 37.9 0.0 5.9 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 EGO56645.1 - 2.4e-22 77.5 8.1 3.5e-06 26.5 0.0 8.0 8 1 0 8 8 8 5 Ankyrin repeat SPX PF03105.14 EGO56645.1 - 3.2e-19 69.7 12.3 3.2e-13 50.0 0.9 2.6 2 1 1 3 3 3 2 SPX domain Ank_5 PF13857.1 EGO56645.1 - 1.1e-17 63.6 6.9 1.4e-05 25.1 0.0 6.3 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO56645.1 - 2.5e-16 58.1 3.7 0.0005 20.0 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat GDPD PF03009.12 EGO56645.1 - 1.6e-11 44.2 0.1 2.7e-10 40.2 0.0 2.7 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DRAT PF07357.6 EGO56645.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) CUE PF02845.11 EGO56646.1 - 7.3e-13 47.7 0.0 1.3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF2638 PF10937.3 EGO56646.1 - 4.5 8.3 9.0 0.52 11.3 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2638) Snf7 PF03357.16 EGO56647.1 - 6.5e-38 129.7 9.1 7.3e-38 129.6 6.3 1.0 1 0 0 1 1 1 1 Snf7 Cytadhesin_P30 PF07271.6 EGO56647.1 - 0.0045 16.3 2.8 0.0055 16.0 1.9 1.3 1 0 0 1 1 1 1 Cytadhesin P30/P32 DUF2520 PF10728.4 EGO56647.1 - 0.0049 16.3 0.1 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2520) GSH_synth_ATP PF03917.12 EGO56647.1 - 0.028 13.0 1.4 0.034 12.7 0.8 1.3 1 1 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain V-SNARE_C PF12352.3 EGO56647.1 - 0.55 10.3 4.8 14 5.8 0.0 3.1 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus DUF1843 PF08898.5 EGO56647.1 - 1.1 9.2 6.8 14 5.7 0.7 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DUF2203 PF09969.4 EGO56647.1 - 3 8.0 6.3 6.3 7.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2293 PF10056.4 EGO56648.1 - 2.8e-26 91.3 0.4 2.8e-26 91.3 0.2 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) CDC45 PF02724.9 EGO56648.1 - 0.15 10.0 4.6 0.24 9.3 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Dicty_REP PF05086.7 EGO56648.1 - 0.16 9.6 1.4 0.24 9.1 1.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nucleoplasmin PF03066.10 EGO56648.1 - 9.5 5.7 11.7 19 4.7 8.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin OB_NTP_bind PF07717.11 EGO56649.1 - 7.6e-24 83.7 0.0 1.4e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGO56649.1 - 5.5e-22 77.7 0.0 1.3e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGO56649.1 - 9.4e-11 41.4 0.0 1.9e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGO56649.1 - 2.6e-05 24.3 0.0 5.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EGO56649.1 - 0.00081 18.9 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 EGO56649.1 - 0.0018 18.1 0.1 0.35 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EGO56649.1 - 0.0066 15.3 0.1 0.023 13.6 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 EGO56649.1 - 0.0094 15.0 0.0 0.02 13.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 EGO56649.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 EGO56649.1 - 0.064 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EGO56649.1 - 0.091 12.1 0.1 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EGO56649.1 - 0.094 13.0 0.1 0.47 10.7 0.1 2.3 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 EGO56649.1 - 0.1 12.0 0.0 0.38 10.1 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EGO56649.1 - 0.38 11.0 2.2 1.1 9.5 1.5 1.8 1 1 0 1 1 1 0 AAA domain DUF485 PF04341.7 EGO56651.1 - 0.29 10.8 0.0 0.48 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 WD40 PF00400.27 EGO56652.1 - 6e-25 86.1 1.0 0.00011 21.8 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 EGO56652.1 - 2e-10 40.5 0.0 2e-10 40.5 0.0 3.5 4 0 0 4 4 4 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EGO56652.1 - 6e-10 39.3 0.4 1.6e-09 37.9 0.3 1.7 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Mvb12 PF09452.5 EGO56652.1 - 0.11 12.6 0.0 0.33 11.1 0.0 1.8 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 Clathrin PF00637.15 EGO56652.1 - 0.19 11.2 0.0 0.59 9.7 0.0 1.8 2 0 0 2 2 2 0 Region in Clathrin and VPS RRM_1 PF00076.17 EGO56653.1 - 1.6e-18 66.0 0.0 2.2e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO56653.1 - 4.7e-14 52.1 0.0 1.1e-13 50.9 0.0 1.6 1 1 1 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO56653.1 - 1.3e-10 40.9 0.0 1.9e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGO56653.1 - 8.6e-05 22.2 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EGO56653.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 RRM_3 PF08777.6 EGO56653.1 - 0.083 12.7 0.0 0.37 10.6 0.0 1.9 1 1 0 1 1 1 0 RNA binding motif RebB PF11747.3 EGO56653.1 - 0.15 11.9 0.0 7 6.6 0.0 2.1 2 0 0 2 2 2 0 Killing trait B12D PF06522.6 EGO56654.1 - 7.1e-12 44.8 0.0 1.1e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit COX6B PF02297.12 EGO56655.1 - 4.2e-18 65.1 4.3 4.9e-18 64.9 3.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EGO56655.1 - 0.0026 17.1 0.3 0.0039 16.5 0.2 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain ketoacyl-synt PF00109.21 EGO56655.1 - 0.13 11.7 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Telomere_Sde2 PF13019.1 EGO56656.1 - 1.9e-64 216.2 0.4 3.2e-64 215.4 0.3 1.4 1 0 0 1 1 1 1 Telomere stability and silencing K_channel_TID PF07941.6 EGO56656.1 - 0.09 13.0 4.5 0.25 11.6 3.1 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Serglycin PF04360.7 EGO56656.1 - 0.7 9.6 3.9 0.38 10.4 0.8 1.8 2 0 0 2 2 2 0 Serglycin DUF2407 PF10302.4 EGO56656.1 - 1.9 8.7 10.8 0.86 9.8 1.0 3.3 2 2 0 2 2 2 0 DUF2407 ubiquitin-like domain Sox_N PF12444.3 EGO56656.1 - 3.9 8.6 6.9 5.1 8.2 0.1 3.0 2 1 1 3 3 3 0 Sox developmental protein N terminal S10_plectin PF03501.10 EGO56657.1 - 1.1e-36 124.5 0.1 1.3e-36 124.3 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Enkurin PF13864.1 EGO56658.1 - 0.056 13.6 0.1 0.094 12.9 0.1 1.3 1 0 0 1 1 1 0 Calmodulin-binding SRP72 PF08492.7 EGO56658.1 - 0.087 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 SRP72 RNA-binding domain HLH PF00010.21 EGO56659.1 - 2.5e-06 27.0 0.0 8.4e-06 25.3 0.0 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3493 PF11998.3 EGO56660.1 - 0.046 13.6 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3493) GET2 PF08690.5 EGO56661.1 - 2.6e-08 33.4 2.8 0.00034 19.9 1.2 2.6 2 1 0 2 2 2 2 GET complex subunit GET2 CAML PF14963.1 EGO56661.1 - 0.0029 17.0 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Calcium signal-modulating cyclophilin ligand PepSY_TM_3 PF13706.1 EGO56661.1 - 0.35 10.3 2.7 0.74 9.2 1.9 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix XK-related PF09815.4 EGO56662.1 - 0.012 14.6 0.4 0.12 11.3 0.1 2.2 2 0 0 2 2 2 0 XK-related protein ATP-synt_8 PF00895.15 EGO56662.1 - 0.03 14.5 0.1 1.6 8.9 0.1 2.6 2 0 0 2 2 2 0 ATP synthase protein 8 DUF4131 PF13567.1 EGO56662.1 - 0.049 13.0 1.0 0.18 11.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2370 PF10176.4 EGO56662.1 - 0.1 11.9 1.1 1.6 8.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2370) SIT PF15330.1 EGO56662.1 - 0.13 12.4 1.2 1.2 9.3 0.0 2.6 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT Coa1 PF08695.5 EGO56663.1 - 1.3e-42 143.9 0.0 1.7e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF814 PF05670.8 EGO56664.1 - 2e-14 53.2 0.0 3.8e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) PAZ_siRNAbind PF12212.3 EGO56664.1 - 0.12 12.0 0.5 0.34 10.5 0.4 1.8 1 0 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain RsgI_N PF12791.2 EGO56664.1 - 2.1 8.0 4.6 0.87 9.2 0.6 2.4 2 1 0 2 2 2 0 Anti-sigma factor N-terminus PITH PF06201.8 EGO56665.1 - 3.3e-47 160.0 0.1 4e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain Rrn6 PF10214.4 EGO56666.1 - 2.6e-198 660.7 0.0 2.9e-198 660.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.7 EGO56667.1 - 1.3e-22 79.5 0.2 4.5e-22 77.8 0.0 2.0 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Atg14 PF10186.4 EGO56667.1 - 0.019 13.8 6.6 0.027 13.4 4.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PRCC PF10253.4 EGO56667.1 - 0.2 12.3 7.0 0.31 11.7 4.9 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting FUSC PF04632.7 EGO56667.1 - 0.97 7.7 8.6 1.2 7.4 6.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF342 PF03961.8 EGO56667.1 - 1.7 6.9 5.7 2.3 6.5 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 EGO56667.1 - 5.5 6.6 15.6 5.2 6.7 3.9 2.2 1 1 1 2 2 2 0 Mnd1 family MOZART1 PF12554.3 EGO56668.1 - 1.4e-21 75.7 0.3 2.4e-21 74.9 0.2 1.4 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated zinc_ribbon_6 PF14599.1 EGO56669.1 - 1e-25 89.2 2.7 1e-25 89.2 1.9 4.3 3 1 2 5 5 5 1 Zinc-ribbon zf-CHY PF05495.7 EGO56669.1 - 5.1e-17 61.8 19.3 5.1e-17 61.8 13.4 4.4 2 1 0 2 2 2 1 CHY zinc finger zf-RING_2 PF13639.1 EGO56669.1 - 7.9e-08 32.0 10.3 7.9e-08 32.0 7.1 4.9 4 1 1 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO56669.1 - 4.7e-07 29.7 7.9 4.7e-07 29.7 5.5 5.4 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO56669.1 - 8.5e-05 22.2 8.9 8.5e-05 22.2 6.2 6.0 3 1 3 6 6 6 1 zinc-RING finger domain PBP1_TM PF14812.1 EGO56669.1 - 2 8.8 18.1 4.2 7.7 0.1 3.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spb1_C PF07780.7 EGO56669.1 - 5.8 6.3 7.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Spb1 C-terminal domain HECT PF00632.20 EGO56671.1 - 5.8e-81 272.0 0.0 8.2e-81 271.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IMS PF00817.15 EGO56672.1 - 8.3e-30 103.5 0.0 1.3e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EGO56672.1 - 1.9e-06 27.8 0.0 5.1e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EGO56672.1 - 7.4e-05 22.5 0.0 0.00022 21.1 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif HHH PF00633.18 EGO56672.1 - 0.0012 18.4 0.0 0.03 14.0 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EGO56672.1 - 0.051 13.7 0.1 0.23 11.6 0.0 2.3 2 1 0 2 2 2 0 Helix-hairpin-helix domain tRNA_anti-like PF12869.2 EGO56672.1 - 0.09 12.2 0.1 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA_anti-like WD40 PF00400.27 EGO56673.1 - 2.6e-16 58.7 4.3 0.0029 17.4 0.0 7.3 8 0 0 8 8 8 4 WD domain, G-beta repeat IncA PF04156.9 EGO56674.1 - 0.0032 17.0 6.4 0.0032 17.0 4.4 3.2 3 1 0 3 3 3 1 IncA protein BCDHK_Adom3 PF10436.4 EGO56677.1 - 6.4e-71 237.1 0.0 9.3e-71 236.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EGO56677.1 - 1.3e-17 63.4 0.0 3.6e-17 62.0 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGO56677.1 - 0.0078 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyridoxal_deC PF00282.14 EGO56678.1 - 1.7e-20 72.8 0.0 3.2e-20 71.9 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EGO56678.1 - 1e-05 24.4 0.0 1.7e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EGO56678.1 - 0.00033 19.8 0.0 0.00054 19.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF4248 PF14053.1 EGO56678.1 - 0.037 13.5 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) Glyco_transf_34 PF05637.7 EGO56679.1 - 3.3e-83 278.8 0.0 4e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EGO56679.1 - 0.0013 18.1 0.0 0.3 10.3 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function, DUF273 RINGv PF12906.2 EGO56680.1 - 7.4e-10 38.7 5.2 1.1e-09 38.1 1.0 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EGO56680.1 - 0.00052 19.7 1.8 0.00052 19.7 1.2 2.2 2 0 0 2 2 2 1 Ring finger domain Cytochrom_B_N PF00033.14 EGO56680.1 - 0.026 13.8 4.7 0.037 13.3 3.3 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB PHD PF00628.24 EGO56680.1 - 0.54 9.9 5.1 0.27 10.9 1.6 1.8 2 0 0 2 2 2 0 PHD-finger Proteasome PF00227.21 EGO56681.1 - 3.3e-57 192.8 0.0 5e-33 114.0 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EGO56681.1 - 2e-11 42.9 0.3 4.3e-11 41.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RCC1_2 PF13540.1 EGO56682.1 - 4.4e-11 42.0 6.6 1.2e-06 27.9 0.1 3.7 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EGO56682.1 - 7.6e-10 38.8 0.5 0.029 14.5 0.2 3.6 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat TFIIIC_delta PF12657.2 EGO56682.1 - 0.1 12.3 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Ribonuclease_3 PF00636.21 EGO56683.1 - 1.6e-34 118.7 0.0 2.7e-17 63.2 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGO56683.1 - 3.6e-26 91.6 0.0 5.6e-12 45.7 0.0 3.8 3 1 0 3 3 3 3 Ribonuclease-III-like Helicase_C PF00271.26 EGO56683.1 - 4e-18 65.0 0.0 3.2e-17 62.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 EGO56683.1 - 1.6e-14 53.4 0.0 4.5e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.24 EGO56683.1 - 1.6e-08 34.2 0.0 3.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 EGO56683.1 - 0.00015 21.1 0.2 0.0015 17.9 0.1 2.3 2 0 0 2 2 2 1 DEAD_2 SNF2_N PF00176.18 EGO56683.1 - 0.01 14.6 0.0 0.03 13.1 0.0 1.7 1 1 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 EGO56683.1 - 0.081 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RFC1 PF08519.7 EGO56684.1 - 5.8e-59 198.2 0.0 1e-58 197.4 0.0 1.4 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EGO56684.1 - 7.3e-14 51.6 0.0 2.1e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EGO56684.1 - 9.1e-09 35.6 0.0 2.6e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EGO56684.1 - 3.6e-07 29.2 0.0 5.9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EGO56684.1 - 7.6e-05 23.5 0.0 7.6e-05 23.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EGO56684.1 - 0.00021 21.4 0.0 0.00094 19.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO56684.1 - 0.00047 20.4 0.1 0.00047 20.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 EGO56684.1 - 0.0016 17.9 0.0 0.0049 16.4 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 EGO56684.1 - 0.0027 17.4 0.0 0.0084 15.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGO56684.1 - 0.0028 17.2 1.2 0.0098 15.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EGO56684.1 - 0.0046 16.9 0.1 0.047 13.6 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EGO56684.1 - 0.016 15.0 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGO56684.1 - 0.02 14.8 1.5 0.036 14.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGO56684.1 - 0.046 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGO56684.1 - 0.048 13.3 0.1 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 NTPase RuvB_N PF05496.7 EGO56684.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EGO56684.1 - 0.13 11.9 0.0 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Ribosomal_L16 PF00252.13 EGO56685.1 - 1.9e-30 105.3 0.4 2.6e-30 104.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Rep_fac_C PF08542.6 EGO56686.1 - 2.3e-23 81.9 0.2 1.5e-22 79.3 0.1 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EGO56686.1 - 4.2e-12 46.0 0.0 9e-12 44.9 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EGO56686.1 - 1.4e-06 28.5 0.0 2.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO56686.1 - 1.3e-05 25.3 0.9 0.00038 20.5 0.2 2.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EGO56686.1 - 0.0001 22.3 1.8 0.041 13.8 0.8 3.1 2 1 0 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.8 EGO56686.1 - 0.0022 17.5 0.1 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Sigma54_activ_2 PF14532.1 EGO56686.1 - 0.0031 17.5 0.2 0.14 12.1 0.1 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 EGO56686.1 - 0.022 14.6 0.1 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGO56686.1 - 0.043 14.1 0.0 0.088 13.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EGO56686.1 - 0.043 13.5 0.0 0.081 12.6 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase SNF2_N PF00176.18 EGO56686.1 - 0.056 12.2 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain T4SS-DNA_transf PF02534.9 EGO56686.1 - 0.063 11.8 0.1 0.14 10.6 0.0 1.5 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer AAA_10 PF12846.2 EGO56686.1 - 0.068 12.6 0.1 2.2 7.6 0.0 2.3 1 1 0 2 2 2 0 AAA-like domain ER_lumen_recept PF00810.13 EGO56687.1 - 9.3e-54 181.9 13.2 9.3e-54 181.9 9.2 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EGO56687.1 - 0.056 12.9 8.0 1.1 8.8 0.2 3.5 2 1 1 3 3 3 0 PQ loop repeat NmrA PF05368.8 EGO56687.1 - 0.12 11.6 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Gly-zipper_OmpA PF13436.1 EGO56689.1 - 0.011 15.3 2.5 0.053 13.1 0.2 2.5 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF533 PF04391.7 EGO56689.1 - 0.015 14.6 0.7 0.024 14.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Rick_17kDa_Anti PF05433.10 EGO56689.1 - 0.071 12.7 0.0 0.071 12.7 0.0 2.8 3 0 0 3 3 3 0 Glycine zipper 2TM domain DUF4366 PF14283.1 EGO56689.1 - 0.091 12.1 0.6 0.13 11.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Zip PF02535.17 EGO56689.1 - 0.19 10.6 1.0 0.27 10.1 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ETRAMP PF09716.5 EGO56689.1 - 2.2 8.2 4.2 2.4 8.1 1.9 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Rgp1 PF08737.5 EGO56690.1 - 2.8e-131 438.4 0.0 1.4e-130 436.1 0.0 2.0 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.24 EGO56690.1 - 0.011 15.5 0.0 0.036 13.8 0.0 1.9 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain DUF4129 PF13559.1 EGO56691.1 - 4.7e-07 29.6 0.3 4.7e-07 29.6 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4129) NICE-3 PF07406.6 EGO56691.1 - 0.042 13.3 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 NICE-3 protein Spore_III_AB PF09548.5 EGO56691.1 - 0.081 12.6 1.4 0.25 11.0 0.9 1.8 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF4375 PF14300.1 EGO56691.1 - 0.1 12.5 0.0 2.6 8.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Herpes_LMP1 PF05297.6 EGO56691.1 - 0.73 8.6 0.0 0.73 8.6 0.0 1.8 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2427 PF10348.4 EGO56691.1 - 0.81 9.3 7.1 1.6 8.3 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF996 PF06195.8 EGO56691.1 - 2.5 8.0 10.4 4 7.4 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF996) DUF2207 PF09972.4 EGO56691.1 - 8 4.9 4.3 13 4.2 3.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ndc1_Nup PF09531.5 EGO56692.1 - 3.6e-157 524.3 0.0 4.1e-157 524.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.1 EGO56693.1 - 1.8e-27 95.3 4.9 2.1e-26 91.9 0.4 2.7 2 1 1 3 3 3 1 Syntaxin-like protein SNARE PF05739.14 EGO56693.1 - 2.9e-19 68.4 3.8 8e-19 67.0 2.7 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EGO56693.1 - 3.9e-05 23.7 1.1 0.00073 19.6 0.0 2.6 2 1 0 2 2 2 1 Syntaxin EspB PF05802.6 EGO56693.1 - 0.0081 15.1 3.3 0.013 14.4 0.2 2.0 2 0 0 2 2 2 1 Enterobacterial EspB protein MCPsignal PF00015.16 EGO56693.1 - 0.015 14.8 1.7 0.077 12.5 0.1 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CCDC155 PF14662.1 EGO56693.1 - 0.021 14.4 6.6 0.061 12.9 4.5 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 T4SS-DNA_transf PF02534.9 EGO56693.1 - 0.038 12.5 0.1 0.047 12.2 0.1 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Vac_Fusion PF02346.11 EGO56693.1 - 0.072 12.5 0.0 0.21 11.0 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus fusion protein 60KD_IMP PF02096.15 EGO56694.1 - 6.5e-13 48.7 0.0 1.8e-12 47.3 0.0 1.7 1 1 1 2 2 2 1 60Kd inner membrane protein EspB PF05802.6 EGO56694.1 - 0.0028 16.6 1.9 0.0044 16.0 1.3 1.2 1 0 0 1 1 1 1 Enterobacterial EspB protein Glycos_transf_1 PF00534.15 EGO56695.1 - 2.2e-23 82.5 0.0 3.3e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGO56695.1 - 1.4e-11 44.7 0.1 3e-10 40.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EGO56695.1 - 0.0049 16.5 0.0 0.0088 15.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase Family 4 tRNA_U5-meth_tr PF05958.6 EGO56696.1 - 1.7e-08 33.5 0.0 2.9e-07 29.5 0.0 2.6 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EGO56696.1 - 2e-07 30.7 0.0 3.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO56696.1 - 0.00016 20.8 0.0 0.00034 19.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EGO56696.1 - 0.00046 20.7 0.0 0.0011 19.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 EGO56696.1 - 0.00095 18.9 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_15 PF09445.5 EGO56696.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EGO56696.1 - 0.0025 17.8 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EGO56696.1 - 0.0055 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltrans_SAM PF10672.4 EGO56696.1 - 0.07 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase TRM PF02005.11 EGO56696.1 - 0.094 11.6 0.1 0.25 10.2 0.0 1.7 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase TOM_sub5 PF15178.1 EGO56696.1 - 0.11 12.2 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM5 homolog Glyco_hydro_72 PF03198.9 EGO56697.1 - 6.5e-116 386.7 4.3 8.1e-116 386.3 3.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EGO56697.1 - 0.00057 19.1 0.2 0.0025 17.0 0.2 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) WLM PF08325.5 EGO56698.1 - 3.1e-49 167.3 0.0 5.2e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EGO56698.1 - 4.5e-05 23.3 0.4 0.00012 21.9 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.4 EGO56698.1 - 0.0053 16.4 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 EGO56698.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily ATP-grasp_2 PF08442.5 EGO56699.1 - 5.5e-08 32.4 0.0 9.8e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Citrate_synt PF00285.16 EGO56701.1 - 1.2e-19 70.3 0.0 6.4e-17 61.3 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 EGO56701.1 - 3.8e-18 65.7 0.1 1.2e-17 64.1 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EGO56701.1 - 2.7e-15 56.2 0.1 4.6e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EGO56701.1 - 3.3e-05 23.4 0.0 0.00074 19.1 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Ribosomal_L30 PF00327.15 EGO56702.1 - 9.6e-17 60.3 0.1 1.7e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MRG PF05712.8 EGO56703.1 - 1.7e-56 190.2 0.5 2.5e-56 189.6 0.3 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EGO56704.1 - 8.5e-08 31.7 0.5 1.7e-07 30.8 0.3 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EGO56704.1 - 0.0045 16.6 1.2 0.0086 15.7 0.9 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cnl2_NKP2 PF09447.5 EGO56705.1 - 9.5e-28 95.6 1.1 1.5e-27 95.0 0.7 1.3 1 0 0 1 1 1 1 Cnl2/NKP2 family protein IncA PF04156.9 EGO56705.1 - 0.032 13.8 1.1 0.081 12.5 0.7 1.7 1 1 0 1 1 1 0 IncA protein CENP-Q PF13094.1 EGO56707.1 - 1.1e-40 139.2 0.3 1.1e-40 139.2 0.2 2.5 3 0 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit CENP-F_leu_zip PF10473.4 EGO56707.1 - 0.15 11.9 5.5 0.34 10.7 1.2 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LicD PF04991.8 EGO56708.1 - 2.4e-41 142.1 1.9 1.2e-40 139.8 0.6 2.2 2 1 0 2 2 2 1 LicD family Etmic-2 PF06670.6 EGO56708.1 - 0.12 11.0 2.0 0.18 10.4 1.4 1.1 1 0 0 1 1 1 0 Microneme protein Etmic-2 TCRP1 PF14944.1 EGO56711.1 - 0.0014 18.5 0.6 0.0016 18.4 0.4 1.0 1 0 0 1 1 1 1 Tongue Cancer Chemotherapy Resistant Protein 1 Fungal_trans PF04082.13 EGO56713.1 - 3.4e-26 91.7 0.0 5.8e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO56713.1 - 1.3e-07 31.3 13.7 2.4e-07 30.5 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Shugoshin_N PF07558.6 EGO56713.1 - 0.034 13.8 0.5 0.071 12.8 0.4 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Herpes_BLRF2 PF05812.7 EGO56713.1 - 0.046 13.5 0.1 0.088 12.6 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Abhydrolase_6 PF12697.2 EGO56715.1 - 2.6e-07 30.7 0.0 4.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO56715.1 - 2.4e-05 24.1 0.0 4.6e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGO56715.1 - 9.7e-05 22.0 0.4 0.00062 19.4 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EGO56715.1 - 0.00023 20.8 0.0 0.68 9.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO56715.1 - 0.022 13.9 0.0 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.15 EGO56715.1 - 0.088 13.0 0.2 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Thioesterase domain Pyridoxal_deC PF00282.14 EGO56717.1 - 1e-75 254.5 0.0 1.5e-75 253.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain FAD_binding_3 PF01494.14 EGO56719.1 - 8.4e-73 245.4 0.0 1.1e-72 245.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGO56719.1 - 5e-47 159.6 0.0 7.8e-47 159.0 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 EGO56719.1 - 0.00036 20.8 0.0 0.0015 18.9 0.0 2.1 3 0 0 3 3 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO56719.1 - 0.0034 17.2 0.0 0.01 15.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO56719.1 - 0.0067 15.3 0.0 0.02 13.8 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EGO56719.1 - 0.011 14.7 0.0 0.023 13.6 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO56719.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGO56719.1 - 0.018 14.1 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family XdhC_C PF13478.1 EGO56719.1 - 0.019 15.2 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain HI0933_like PF03486.9 EGO56719.1 - 0.043 12.2 0.0 0.07 11.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 EGO56719.1 - 0.073 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EGO56719.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EGO56719.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 ThiF family HET PF06985.6 EGO56720.1 - 4.4e-23 81.9 0.7 7.7e-23 81.1 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4050 PF13259.1 EGO56720.1 - 0.094 12.6 0.6 0.18 11.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Abhydrolase_3 PF07859.8 EGO56722.1 - 1.1e-33 116.6 0.0 2.2e-23 82.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 EGO56722.1 - 0.0074 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2424 PF10340.4 EGO56722.1 - 0.062 11.9 0.0 0.096 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) DUF605 PF04652.11 EGO56722.1 - 3.4 6.9 11.5 5.8 6.2 8.0 1.2 1 0 0 1 1 1 0 Vta1 like Herpes_BLLF1 PF05109.8 EGO56722.1 - 5.7 4.7 10.6 8.7 4.1 7.4 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) PepSY_TM_2 PF13703.1 EGO56723.1 - 0.029 14.5 0.6 0.063 13.4 0.4 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix DDHD PF02862.12 EGO56724.1 - 1e-39 136.7 0.0 1.9e-39 135.8 0.0 1.5 1 0 0 1 1 1 1 DDHD domain Abhydrolase_6 PF12697.2 EGO56724.1 - 0.0028 17.5 0.1 0.0084 16.0 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO56724.1 - 0.0031 17.2 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family CRISPR_Cse2 PF09485.5 EGO56724.1 - 0.081 12.9 0.4 0.16 11.9 0.3 1.4 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF2305 PF10230.4 EGO56724.1 - 0.087 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) zf-RING_2 PF13639.1 EGO56726.1 - 1.3e-15 56.9 17.5 4.1e-15 55.3 4.5 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 EGO56726.1 - 5.3e-11 42.0 12.1 8.8e-09 34.9 3.0 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO56726.1 - 8.4e-09 35.3 15.2 5.3e-08 32.7 4.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGO56726.1 - 1e-07 31.9 5.0 1e-07 31.9 3.4 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGO56726.1 - 9e-07 28.5 15.0 2.6e-06 27.0 3.1 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.20 EGO56726.1 - 1.1e-06 28.1 15.1 1.2e-05 24.9 3.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 EGO56726.1 - 0.00073 19.1 1.2 0.00073 19.1 0.8 2.4 2 1 0 2 2 2 1 Hydrogenase expression/synthesis hypA family zf-Apc11 PF12861.2 EGO56726.1 - 0.0028 17.4 3.2 0.0028 17.4 2.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGO56726.1 - 0.35 10.4 14.0 0.99 9.0 1.7 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EGO56726.1 - 0.37 10.3 10.6 0.043 13.3 3.8 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.1 EGO56726.1 - 0.41 10.3 10.8 3.3 7.4 0.3 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_3 PF14369.1 EGO56726.1 - 0.65 10.0 8.9 0.72 9.8 2.6 2.7 2 0 0 2 2 2 0 zinc-finger PHD PF00628.24 EGO56726.1 - 4.7 6.9 14.1 7.1 6.4 1.4 2.7 2 0 0 2 2 2 0 PHD-finger HET PF06985.6 EGO56727.1 - 4.7e-10 39.7 0.0 4.7e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UNC45-central PF11701.3 EGO56729.1 - 3.8e-52 176.0 0.4 2.1e-49 167.2 0.0 3.4 3 1 0 3 3 3 2 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 EGO56729.1 - 2.2e-06 27.8 12.3 1.2 9.4 0.1 6.2 4 1 2 6 6 6 4 HEAT repeats HEAT PF02985.17 EGO56729.1 - 0.0079 16.1 3.6 3.8 7.8 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 EGO56729.1 - 0.037 14.5 8.4 2.1 8.9 0.0 5.2 5 0 0 5 5 5 0 HEAT-like repeat zf-DNL PF05180.7 EGO56731.1 - 0.12 12.1 2.7 0.27 10.9 1.8 1.5 1 0 0 1 1 1 0 DNL zinc finger Helicase_C_4 PF13871.1 EGO56732.1 - 0.037 13.4 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Helicase_C-like CDC45 PF02724.9 EGO56732.1 - 0.039 11.9 3.5 0.052 11.5 2.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 EGO56732.1 - 0.074 11.1 0.9 0.11 10.5 0.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_RNA_Pol_19 PF05320.7 EGO56732.1 - 0.19 11.4 5.8 1.9 8.2 2.7 2.2 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Sporozoite_P67 PF05642.6 EGO56732.1 - 0.23 9.2 7.7 0.037 11.9 2.9 1.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Nop14 PF04147.7 EGO56732.1 - 2 6.2 11.8 0.36 8.7 5.7 1.4 2 0 0 2 2 2 0 Nop14-like family VID27 PF08553.5 EGO56732.1 - 3.9 5.5 6.5 5.4 5.1 4.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein CENP-B_dimeris PF09026.5 EGO56732.1 - 6 7.1 14.8 14 5.9 10.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CorA PF01544.13 EGO56733.1 - 0.0046 16.0 4.2 0.011 14.8 2.9 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein KLRAQ PF10205.4 EGO56733.1 - 0.023 14.7 0.6 0.077 13.0 0.4 1.9 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF2207 PF09972.4 EGO56733.1 - 0.096 11.2 0.1 0.14 10.7 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) D5_N PF08706.6 EGO56733.1 - 0.29 11.1 1.9 0.64 10.1 0.1 2.3 3 0 0 3 3 3 0 D5 N terminal like ERCC4 PF02732.10 EGO56734.1 - 1.2e-18 67.2 0.3 2.1e-18 66.4 0.2 1.4 1 0 0 1 1 1 1 ERCC4 domain RR_TM4-6 PF06459.7 EGO56734.1 - 0.35 10.7 7.5 0.96 9.2 5.2 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1682 PF07946.9 EGO56734.1 - 5.9 5.6 18.4 13 4.4 12.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Kinesin PF00225.18 EGO56737.1 - 5.3e-89 298.2 0.0 5.3e-89 298.2 0.0 3.7 4 0 0 4 4 4 1 Kinesin motor domain Reprolysin_5 PF13688.1 EGO56738.1 - 6.5e-60 202.4 3.1 6.5e-60 202.4 2.1 2.5 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EGO56738.1 - 7.3e-48 162.8 0.2 1.6e-47 161.7 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EGO56738.1 - 4.9e-46 156.9 0.8 4.9e-46 156.9 0.5 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EGO56738.1 - 2.8e-20 73.1 0.1 7.8e-20 71.6 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EGO56738.1 - 6e-17 61.6 33.7 6e-17 61.6 23.3 4.8 3 1 1 4 4 4 1 Disintegrin Reprolysin PF01421.14 EGO56738.1 - 0.0034 16.9 8.2 0.0034 16.9 5.7 3.3 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease AMP-binding PF00501.23 EGO56739.1 - 2.6e-91 306.0 0.4 3.2e-91 305.7 0.3 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO56739.1 - 4.8e-22 78.7 0.7 3.9e-19 69.3 0.3 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain UvrD-helicase PF00580.16 EGO56740.1 - 1.5e-13 50.7 1.9 1.3e-08 34.5 0.0 2.9 1 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EGO56740.1 - 1.4e-09 37.9 0.0 3.7e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EGO56740.1 - 2.8e-05 23.8 0.1 6.5e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain DEAD PF00270.24 EGO56740.1 - 0.00015 21.2 0.0 0.00035 20.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGO56740.1 - 0.00016 21.8 0.0 0.00058 20.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EGO56740.1 - 0.00017 21.1 0.0 0.97 8.9 0.0 3.3 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.1 EGO56740.1 - 0.00025 20.6 0.0 0.00042 19.8 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 EGO56740.1 - 0.003 17.1 0.2 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EGO56740.1 - 0.0079 15.5 0.0 0.021 14.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO56740.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 EGO56741.1 - 9.3e-11 41.3 0.0 1.5e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGO56741.1 - 0.005 16.6 0.0 0.0098 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EGO56741.1 - 0.022 13.8 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase DUF605 PF04652.11 EGO56741.1 - 0.34 10.2 14.9 0.52 9.6 10.3 1.2 1 0 0 1 1 1 0 Vta1 like Totivirus_coat PF05518.6 EGO56741.1 - 1.7 6.3 4.7 2.3 5.9 3.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein WD40 PF00400.27 EGO56744.1 - 8.4e-13 47.6 6.0 0.0014 18.3 0.0 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 EGO56744.1 - 5.2e-05 23.0 0.0 2 8.0 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EGO56744.1 - 0.014 14.1 0.0 0.073 11.8 0.0 2.0 2 0 0 2 2 2 0 Nup133 N terminal like Apc4_WD40 PF12894.2 EGO56744.1 - 0.026 14.0 0.1 24 4.5 0.0 3.9 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Macoilin PF09726.4 EGO56744.1 - 9.1 4.4 9.2 12 4.0 6.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1751 PF08551.5 EGO56745.1 - 2.4e-29 101.5 4.1 5e-29 100.5 2.9 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EGO56745.1 - 0.76 9.7 11.9 3.7 7.5 7.5 2.1 2 0 0 2 2 2 0 Rhomboid family Lig_chan PF00060.21 EGO56745.1 - 0.94 9.1 3.4 1.7 8.3 2.4 1.5 1 0 0 1 1 1 0 Ligand-gated ion channel MARVEL PF01284.18 EGO56745.1 - 1.3 8.8 11.9 10 5.9 8.3 2.2 1 1 0 1 1 1 0 Membrane-associating domain TPR_1 PF00515.23 EGO56749.1 - 2.7e-59 194.4 27.7 4.8e-08 32.2 0.0 11.0 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 EGO56749.1 - 3e-53 177.3 42.6 2.1e-13 49.6 1.5 6.6 2 2 5 8 8 8 8 TPR repeat TPR_2 PF07719.12 EGO56749.1 - 6.8e-52 169.2 21.6 1.1e-06 28.0 0.0 10.5 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.1 EGO56749.1 - 1.7e-40 133.7 16.2 9.1e-07 28.2 0.6 10.3 8 1 2 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 EGO56749.1 - 1.7e-37 127.2 15.0 1.1e-08 35.4 0.0 6.8 4 1 3 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 EGO56749.1 - 6.8e-34 115.6 19.2 5.6e-07 29.3 0.1 6.9 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.1 EGO56749.1 - 1.9e-31 105.6 13.9 3e-05 24.2 0.0 10.2 3 2 7 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.1 EGO56749.1 - 1.8e-29 99.4 18.8 0.0018 18.3 0.0 10.5 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_6 PF13174.1 EGO56749.1 - 5.8e-25 85.9 12.7 0.00025 21.2 0.0 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGO56749.1 - 1.1e-24 86.5 20.9 0.00016 21.9 0.2 6.2 4 1 3 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 EGO56749.1 - 5.6e-19 66.3 20.1 0.0012 18.4 0.1 10.1 9 2 1 10 10 9 5 Tetratricopeptide repeat TPR_9 PF13371.1 EGO56749.1 - 2.1e-18 65.9 14.9 0.0049 16.6 0.1 7.7 1 1 7 8 8 8 6 Tetratricopeptide repeat Apc3 PF12895.2 EGO56749.1 - 1.8e-15 56.8 12.3 6.1e-07 29.4 1.5 4.0 3 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EGO56749.1 - 8.9e-13 47.9 7.6 1.1e-05 24.6 0.7 4.3 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 EGO56749.1 - 7.9e-05 22.7 6.3 0.076 13.1 0.1 4.3 5 1 1 6 6 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGO56749.1 - 0.00036 20.3 5.9 0.77 9.6 0.0 5.1 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat SNAP PF14938.1 EGO56749.1 - 0.051 12.7 13.3 5.9 5.9 0.8 4.5 2 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP ChAPs PF09295.5 EGO56749.1 - 0.065 11.9 2.0 7.4 5.2 0.2 2.8 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.4 EGO56749.1 - 0.35 10.7 18.4 0.36 10.7 0.0 4.8 4 2 2 6 6 5 0 Tetratricopeptide repeat DUF2852 PF11014.3 EGO56749.1 - 0.71 9.8 6.2 1.8 8.5 4.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) TPR_10 PF13374.1 EGO56749.1 - 0.9 9.5 29.7 6.4 6.8 0.0 8.1 10 0 0 10 10 8 0 Tetratricopeptide repeat Asp-B-Hydro_N PF05279.6 EGO56749.1 - 4.2 7.1 8.6 5.9 6.6 4.4 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Ribosomal_L3 PF00297.17 EGO56750.1 - 1.9e-117 391.3 9.8 2.2e-117 391.1 6.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 adh_short PF00106.20 EGO56752.1 - 2.3e-26 92.6 1.8 4.2e-26 91.8 1.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO56752.1 - 5.6e-13 49.2 0.0 8.3e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO56752.1 - 3.5e-07 30.0 6.4 2.3e-06 27.4 4.5 2.2 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGO56752.1 - 0.019 14.0 0.1 0.032 13.3 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MadL PF03817.8 EGO56752.1 - 0.035 13.9 0.1 0.17 11.7 0.1 2.1 1 1 0 1 1 1 0 Malonate transporter MadL subunit NAD_binding_10 PF13460.1 EGO56752.1 - 0.036 14.0 0.5 0.067 13.2 0.1 1.6 2 0 0 2 2 2 0 NADH(P)-binding Sugar_tr PF00083.19 EGO56753.1 - 2.4e-111 372.4 21.5 3.1e-111 372.1 14.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO56753.1 - 3e-25 88.6 35.9 4e-25 88.2 19.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EGO56754.1 - 2.6e-37 128.3 43.0 2.6e-37 128.3 29.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO56754.1 - 7.8e-10 37.9 15.7 7.8e-10 37.9 10.9 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter T2SJ PF11612.3 EGO56755.1 - 0.014 15.1 0.0 0.015 15.0 0.0 1.0 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J MucB_RseB PF03888.9 EGO56755.1 - 0.017 14.1 0.0 0.017 14.1 0.0 1.0 1 0 0 1 1 1 0 MucB/RseB family Glyco_hydro_72 PF03198.9 EGO56756.1 - 1.9e-92 309.6 0.1 3.6e-91 305.4 0.1 2.1 1 1 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EGO56756.1 - 0.0055 15.6 0.0 0.0073 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Zip PF02535.17 EGO56757.1 - 0.078 11.9 0.4 0.17 10.8 0.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Apolipoprotein PF01442.13 EGO56759.1 - 0.00048 19.6 45.0 0.00048 19.6 31.2 3.4 2 1 1 3 3 3 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 EGO56759.1 - 0.0023 17.7 37.3 0.046 13.5 3.2 5.1 2 1 1 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EGO56759.1 - 0.033 13.3 20.4 0.031 13.4 2.8 4.1 1 1 3 4 4 4 0 Reovirus sigma C capsid protein Filament PF00038.16 EGO56759.1 - 0.78 9.1 63.9 0.04 13.3 11.6 4.6 2 2 1 3 3 3 0 Intermediate filament protein DUF3584 PF12128.3 EGO56759.1 - 4.1 4.6 66.8 0.88 6.8 23.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TIP49 PF06068.8 EGO56760.1 - 1.1e-175 584.1 3.8 1.3e-175 583.9 2.7 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EGO56760.1 - 1.7e-08 33.8 2.1 6.9e-06 25.2 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EGO56760.1 - 3.8e-08 33.6 1.2 4.3e-05 23.7 0.1 3.0 1 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 EGO56760.1 - 7e-07 28.3 0.6 1.2e-06 27.5 0.4 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EGO56760.1 - 4.5e-06 26.7 0.0 7.4e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO56760.1 - 3.4e-05 24.0 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGO56760.1 - 0.00034 20.0 0.0 0.0007 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGO56760.1 - 0.00063 18.9 0.6 0.013 14.6 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EGO56760.1 - 0.00063 19.6 0.0 0.81 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EGO56760.1 - 0.0048 16.3 0.1 2.1 7.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 EGO56760.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGO56760.1 - 0.016 14.9 0.9 0.84 9.3 0.0 3.0 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EGO56760.1 - 0.021 14.5 1.1 0.049 13.3 0.3 1.9 1 1 1 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EGO56760.1 - 0.045 13.6 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EGO56760.1 - 0.057 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_32 PF13654.1 EGO56760.1 - 0.06 12.0 0.1 0.16 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EGO56760.1 - 0.065 12.7 0.2 0.11 12.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGO56760.1 - 0.073 12.1 0.2 0.15 11.1 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.12 EGO56760.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 GYF PF02213.11 EGO56761.1 - 2.3e-10 39.9 0.3 4.3e-10 39.0 0.2 1.5 1 0 0 1 1 1 1 GYF domain Gluconate_2-dh3 PF13618.1 EGO56761.1 - 0.72 10.0 8.0 5.9 7.0 5.6 2.5 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 UFD1 PF03152.9 EGO56762.1 - 3.7e-67 224.8 0.0 4.7e-67 224.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 F-box-like PF12937.2 EGO56763.1 - 0.026 14.2 0.9 0.05 13.3 0.6 1.5 1 0 0 1 1 1 0 F-box-like COPI_C PF06957.6 EGO56763.1 - 0.12 10.8 2.6 0.23 9.9 1.8 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DUF3176 PF11374.3 EGO56764.1 - 1.1e-26 92.8 2.6 2.4e-26 91.8 1.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Imm_superinfect PF14373.1 EGO56764.1 - 1.4 8.5 5.1 12 5.6 0.4 2.6 2 0 0 2 2 2 0 Superinfection immunity protein DUF572 PF04502.8 EGO56770.1 - 0.00092 18.5 1.0 0.00092 18.5 0.7 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF572) DUF4322 PF14210.1 EGO56770.1 - 0.14 11.6 0.0 0.38 10.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) Herpes_UL20 PF04544.7 EGO56771.1 - 0.034 13.9 0.1 0.057 13.2 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus egress protein UL20 DUF1908 PF08926.6 EGO56775.1 - 0.023 13.4 0.1 0.041 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) TFIIA PF03153.8 EGO56775.1 - 4.5 7.0 28.2 7.8 6.2 16.5 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FAM217 PF15344.1 EGO56779.1 - 0.0087 15.6 1.1 0.011 15.2 0.8 1.2 1 0 0 1 1 1 1 FAM217 family HTH_AsnC-type PF13404.1 EGO56779.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Pox_Ag35 PF03286.9 EGO56779.1 - 2.1 7.8 8.9 2.6 7.5 6.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein VEFS-Box PF09733.4 EGO56781.1 - 3.8e-06 26.6 0.0 8.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 VEFS-Box of polycomb protein AAA PF00004.24 EGO56782.1 - 1.2e-35 122.5 0.0 2.5e-35 121.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGO56782.1 - 3.6e-05 24.5 0.1 0.00029 21.6 0.0 2.7 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EGO56782.1 - 6.8e-05 22.0 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGO56782.1 - 0.00018 21.6 1.0 0.0065 16.6 0.1 3.4 2 2 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EGO56782.1 - 0.00026 21.0 10.5 0.00037 20.5 0.5 4.5 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 EGO56782.1 - 0.00026 20.4 0.0 0.00076 18.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EGO56782.1 - 0.00086 19.2 0.0 0.0075 16.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EGO56782.1 - 0.0035 17.2 0.0 0.011 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO56782.1 - 0.0038 16.9 0.1 0.014 15.1 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EGO56782.1 - 0.012 15.8 0.2 0.065 13.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EGO56782.1 - 0.013 15.2 0.1 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RIX1 PF08167.7 EGO56782.1 - 0.015 15.0 0.0 6.7 6.3 0.0 2.4 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis TIP49 PF06068.8 EGO56782.1 - 0.018 13.7 0.0 0.032 12.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 EGO56782.1 - 0.023 13.8 0.0 0.06 12.5 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EGO56782.1 - 0.027 14.5 0.0 0.095 12.7 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF3069 PF11269.3 EGO56782.1 - 0.029 14.4 0.2 0.1 12.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3069) RNA_helicase PF00910.17 EGO56782.1 - 0.053 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EGO56782.1 - 0.063 12.8 0.2 0.18 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EGO56782.1 - 0.065 12.7 0.4 0.3 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mus7 PF09462.5 EGO56783.1 - 2.6e-211 703.6 0.1 3.9e-211 703.1 0.1 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family tRNA-synt_His PF13393.1 EGO56783.1 - 0.021 13.8 0.3 0.042 12.8 0.2 1.4 1 0 0 1 1 1 0 Histidyl-tRNA synthetase COX4 PF02936.9 EGO56785.1 - 4.4e-56 188.5 0.1 5.3e-56 188.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.6 EGO56785.1 - 0.035 14.2 0.1 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DAO PF01266.19 EGO56787.1 - 3e-50 171.1 0.0 4.4e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO56787.1 - 4.7e-08 32.2 0.1 1.3e-07 30.8 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EGO56787.1 - 4.5e-07 29.3 0.9 1.3e-05 24.4 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO56787.1 - 7.8e-05 22.6 0.0 0.00023 21.1 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO56787.1 - 0.00075 18.6 0.3 0.007 15.4 0.1 2.1 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.13 EGO56787.1 - 0.0011 18.6 0.1 0.002 17.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EGO56787.1 - 0.002 18.0 0.1 0.0058 16.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGO56787.1 - 0.0038 15.7 0.4 0.0061 15.0 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EGO56787.1 - 0.0075 15.3 0.1 0.017 14.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EGO56787.1 - 0.012 14.5 0.1 0.029 13.2 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EGO56787.1 - 0.012 16.0 0.6 0.035 14.5 0.4 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO56787.1 - 0.026 14.5 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO56787.1 - 0.028 13.3 0.0 0.13 11.1 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EGO56787.1 - 0.052 13.6 0.0 0.76 9.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PALP PF00291.20 EGO56787.1 - 0.055 12.7 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme NAD_binding_10 PF13460.1 EGO56787.1 - 0.088 12.7 0.3 0.37 10.7 0.1 2.1 3 0 0 3 3 3 0 NADH(P)-binding GDI PF00996.13 EGO56787.1 - 0.16 10.2 0.1 0.29 9.3 0.0 1.4 1 0 0 1 1 1 0 GDP dissociation inhibitor TPT PF03151.11 EGO56788.1 - 3e-42 143.8 0.9 3e-42 143.8 0.6 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EGO56788.1 - 3.6e-09 35.9 9.9 3.6e-08 32.6 6.9 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGO56788.1 - 6.3e-06 26.2 29.7 0.0006 19.8 7.0 3.5 2 2 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EGO56788.1 - 0.0067 15.5 0.4 0.073 12.1 0.0 2.3 2 1 0 2 2 2 1 Nucleotide-sugar transporter DUF914 PF06027.7 EGO56788.1 - 0.035 12.9 0.9 0.17 10.7 0.1 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) Multi_Drug_Res PF00893.14 EGO56788.1 - 2.5 8.6 8.1 1.2 9.7 0.4 3.3 3 1 0 4 4 4 0 Small Multidrug Resistance protein DUF382 PF04037.8 EGO56789.1 - 6.9e-63 210.2 1.4 6.9e-63 210.2 1.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EGO56789.1 - 2.9e-21 74.5 3.2 2.9e-21 74.5 2.3 2.7 3 0 0 3 3 3 1 PSP Dickkopf_N PF04706.7 EGO56791.1 - 2.1 8.5 5.5 3.7 7.7 0.7 2.3 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region RGS PF00615.14 EGO56797.1 - 3.5e-12 46.4 0.0 5.9e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain DMAP_binding PF06464.6 EGO56797.1 - 0.2 12.2 1.3 3.1 8.4 0.3 2.6 2 0 0 2 2 2 0 DMAP1-binding Domain ORC5_C PF14630.1 EGO56798.1 - 7.4e-76 255.1 0.0 8.1e-74 248.4 0.0 2.1 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EGO56798.1 - 1.6e-12 47.7 0.1 5.4e-12 46.0 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EGO56798.1 - 0.0019 17.8 0.0 0.0042 16.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ashwin PF15323.1 EGO56798.1 - 0.021 14.8 1.7 0.034 14.1 1.2 1.2 1 0 0 1 1 1 0 Developmental protein AAA_22 PF13401.1 EGO56798.1 - 0.038 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGO56798.1 - 0.079 12.4 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.8 EGO56798.1 - 0.18 10.7 0.0 0.4 9.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 EGO56799.1 - 3.1e-62 209.8 0.0 4.6e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGO56799.1 - 7.5e-25 87.5 0.6 1.4e-24 86.7 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGO56799.1 - 9.5e-24 83.4 0.4 5.6e-23 80.9 0.2 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.24 EGO56799.1 - 0.0034 17.5 0.0 0.49 10.5 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EGO56799.1 - 0.0046 16.6 0.3 1.1 8.9 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EGO56799.1 - 0.01 15.2 0.1 0.051 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EGO56799.1 - 0.012 15.2 0.0 0.03 14.0 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 EGO56799.1 - 0.016 14.4 0.1 0.031 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EGO56799.1 - 0.027 14.1 0.2 0.075 12.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EGO56799.1 - 0.035 14.1 0.4 0.34 10.8 0.0 2.4 1 1 0 2 2 2 0 AAA ATPase domain KaiC PF06745.8 EGO56799.1 - 0.035 13.2 0.1 0.059 12.4 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 EGO56799.1 - 0.056 13.5 0.1 0.2 11.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EGO56799.1 - 0.066 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase EKR PF10371.4 EGO56799.1 - 0.12 11.9 0.2 1.4 8.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function NB-ARC PF00931.17 EGO56799.1 - 0.13 11.0 0.7 0.62 8.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain Alpha-amylase_C PF02806.13 EGO56800.1 - 4.8e-25 87.5 0.1 2.7e-24 85.1 0.0 2.4 3 0 0 3 3 3 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EGO56800.1 - 1.1e-19 70.9 0.0 2e-14 53.7 0.0 2.6 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EGO56800.1 - 3.1e-18 65.5 0.0 8.8e-18 64.1 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Cellulase PF00150.13 EGO56800.1 - 0.029 13.5 0.0 0.18 10.9 0.0 2.0 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) AAA_2 PF07724.9 EGO56801.1 - 4.1e-34 117.9 0.0 1.4e-31 109.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EGO56801.1 - 6.3e-13 49.0 0.0 1.3e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EGO56801.1 - 3.9e-09 36.2 0.0 8.2e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EGO56801.1 - 5.2e-08 32.7 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EGO56801.1 - 0.0002 21.2 0.0 0.00045 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO56801.1 - 0.00025 21.8 0.0 0.00074 20.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain MCM PF00493.18 EGO56801.1 - 0.00031 19.6 0.5 0.00057 18.7 0.0 1.6 2 0 0 2 2 2 1 MCM2/3/5 family AAA_22 PF13401.1 EGO56801.1 - 0.00055 20.0 0.1 0.0041 17.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO56801.1 - 0.00081 19.4 0.1 0.026 14.5 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EGO56801.1 - 0.0021 17.5 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 EGO56801.1 - 0.019 15.2 0.1 0.066 13.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGO56801.1 - 0.04 13.0 0.0 0.86 8.7 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 EGO56801.1 - 0.044 12.6 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 EGO56801.1 - 0.048 13.9 0.2 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 EGO56801.1 - 0.061 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.21 EGO56801.1 - 0.093 12.2 0.0 0.43 10.0 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.10 EGO56801.1 - 0.14 11.9 2.2 0.41 10.4 0.0 2.3 2 1 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 EGO56801.1 - 0.17 11.4 0.1 0.32 10.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EGO56802.1 - 1.7e-38 129.1 13.3 1.7e-11 43.4 0.0 6.9 6 1 1 7 7 7 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EGO56802.1 - 0.00066 19.1 0.0 10 5.7 0.0 4.7 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 EGO56802.1 - 0.019 13.8 1.0 0.49 9.1 0.4 2.0 2 0 0 2 2 2 0 Coatomer WD associated region Nop25 PF09805.4 EGO56802.1 - 0.13 12.3 4.3 0.072 13.1 1.0 1.9 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Transket_pyr PF02779.19 EGO56803.1 - 2.1e-63 213.0 0.0 4.9e-63 211.8 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EGO56803.1 - 2.3e-55 187.4 0.0 3.2e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component BSD PF03909.12 EGO56805.1 - 1.2e-30 105.0 5.6 6.7e-15 54.5 0.1 2.8 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EGO56805.1 - 3.7e-25 87.3 0.0 9.4e-25 86.0 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Clathrin_lg_ch PF01086.12 EGO56805.1 - 0.0099 15.8 1.6 0.022 14.6 1.1 1.6 1 0 0 1 1 1 1 Clathrin light chain Med21 PF11221.3 EGO56805.1 - 0.042 13.8 1.3 0.13 12.1 0.9 1.9 1 0 0 1 1 1 0 Subunit 21 of Mediator complex DUF3683 PF12447.3 EGO56805.1 - 0.057 13.2 0.9 0.22 11.3 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) OmpH PF03938.9 EGO56805.1 - 0.16 11.9 3.3 0.35 10.7 1.7 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Clathrin PF00637.15 EGO56806.1 - 1.3e-24 86.3 2.3 3.4e-23 81.8 0.2 3.1 2 1 1 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.3 EGO56806.1 - 8.7e-21 73.5 0.2 3.7e-20 71.5 0.1 2.2 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 EGO56806.1 - 1.9e-06 27.5 0.2 4.1e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Ring finger domain TPR_11 PF13414.1 EGO56806.1 - 0.0033 17.0 0.0 0.013 15.1 0.0 2.1 1 0 0 1 1 1 1 TPR repeat zf-RING_5 PF14634.1 EGO56806.1 - 0.0058 16.3 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain TPR_15 PF13429.1 EGO56806.1 - 0.011 14.8 1.2 0.12 11.3 0.9 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGO56806.1 - 0.012 15.4 0.3 0.012 15.4 0.2 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGO56806.1 - 0.026 14.4 1.3 0.062 13.2 0.0 2.4 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGO56806.1 - 0.048 13.4 2.6 0.12 12.1 0.2 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGO56806.1 - 0.065 13.5 0.8 4.2 7.7 0.1 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGO56806.1 - 0.09 13.4 0.0 16 6.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 EGO56806.1 - 0.7 9.9 4.1 0.32 11.0 0.6 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Apc3 PF12895.2 EGO56806.1 - 1.7 8.8 6.9 14 5.8 0.2 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 BPL_LplA_LipB PF03099.14 EGO56807.1 - 5.1e-15 55.6 0.0 8.6e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.16 EGO56808.1 - 8.9e-126 419.0 0.0 1.7e-125 418.0 0.0 1.4 1 1 0 1 1 1 1 Chorismate synthase HMGL-like PF00682.14 EGO56809.1 - 2.4e-38 132.1 0.0 4.9e-38 131.1 0.0 1.5 1 1 0 1 1 1 1 HMGL-like DS PF01916.12 EGO56810.1 - 7.5e-149 494.7 0.0 8.7e-149 494.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Myb_DNA-binding PF00249.26 EGO56812.1 - 1.6e-13 50.4 0.0 1.8e-05 24.6 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGO56812.1 - 0.0007 19.6 4.9 0.55 10.3 0.4 3.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Syndecan PF01034.15 EGO56813.1 - 0.039 13.5 0.2 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 Syndecan domain FAM163 PF15069.1 EGO56813.1 - 0.043 14.3 2.3 0.17 12.4 0.0 2.6 2 1 0 3 3 3 0 FAM163 family EphA2_TM PF14575.1 EGO56813.1 - 0.059 13.7 2.6 0.46 10.9 0.0 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Suf PF05843.9 EGO56813.1 - 0.13 11.9 2.4 0.22 11.2 1.6 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4446 PF14584.1 EGO56813.1 - 0.29 10.9 2.1 3.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Ctr PF04145.10 EGO56813.1 - 1.4 8.9 0.0 1.4 8.9 0.0 2.6 2 1 0 2 2 2 0 Ctr copper transporter family PAP2 PF01569.16 EGO56814.1 - 0.0054 16.4 2.8 0.27 10.9 0.1 2.2 2 0 0 2 2 2 2 PAP2 superfamily Fungal_trans_2 PF11951.3 EGO56815.1 - 6.7e-57 192.8 0.0 8.7e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EGO56816.1 - 7.2e-29 100.4 0.0 2.3e-27 95.5 0.0 2.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO56816.1 - 3.3e-09 36.4 9.8 5.6e-09 35.7 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.16 EGO56817.1 - 3.7e-91 305.4 0.0 4.7e-91 305.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Chitin_bind_3 PF03067.10 EGO56821.1 - 0.1 12.8 1.0 0.27 11.5 0.0 2.2 2 1 0 2 2 2 0 Chitin binding domain Serglycin PF04360.7 EGO56821.1 - 0.15 11.7 8.9 0.41 10.3 0.6 2.4 2 0 0 2 2 2 0 Serglycin LsmAD PF06741.8 EGO56823.1 - 1e-22 80.0 2.1 1e-22 80.0 1.5 2.3 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 EGO56823.1 - 1.5e-10 40.8 0.1 3.7e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain UCN2 PF11613.3 EGO56823.1 - 0.063 13.2 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 Agonist of corticotropin releasing factor R2, Urocortin-2 MFS_1 PF07690.11 EGO56826.1 - 3.1e-37 128.0 70.7 1.1e-28 100.0 26.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EGO56826.1 - 0.95 9.5 12.5 1.2 9.2 0.5 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) F-box-like PF12937.2 EGO56827.1 - 0.0035 17.0 0.3 0.008 15.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO56827.1 - 0.022 14.4 0.2 0.056 13.1 0.1 1.7 1 0 0 1 1 1 0 F-box domain Cupin_8 PF13621.1 EGO56829.1 - 1.1e-39 136.4 0.0 1.8e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 EGO56829.1 - 8.4e-17 61.3 0.1 2.7e-16 59.6 0.1 1.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase MFS_1 PF07690.11 EGO56829.1 - 6.3e-14 51.4 2.8 6.3e-14 51.4 2.0 2.3 1 1 0 2 2 2 1 Major Facilitator Superfamily Cupin_4 PF08007.7 EGO56829.1 - 2e-05 24.0 0.0 2e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Cupin superfamily protein Kelch_2 PF07646.10 EGO56829.1 - 0.00063 19.4 0.1 0.0035 17.0 0.0 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 EGO56829.1 - 0.005 16.5 0.0 0.005 16.5 0.0 4.2 7 0 0 7 7 7 1 Galactose oxidase, central domain Nodulin-like PF06813.8 EGO56829.1 - 0.61 9.2 9.3 0.52 9.5 3.3 2.6 2 1 0 2 2 2 0 Nodulin-like Mito_carr PF00153.22 EGO56830.1 - 0.043 13.5 0.1 0.069 12.8 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein Mito_carr PF00153.22 EGO56831.1 - 6e-47 157.3 9.6 1.2e-17 63.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C48 PF02902.14 EGO56832.1 - 2.9e-18 66.2 0.0 7.2e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Phlebovirus_NSM PF07246.6 EGO56832.1 - 1.5 7.9 6.5 3.2 6.8 4.5 1.5 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CN_hydrolase PF00795.17 EGO56833.1 - 2.5e-21 75.8 0.0 3.6e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Macoilin PF09726.4 EGO56834.1 - 1.5 6.9 4.2 1.7 6.8 2.9 1.1 1 0 0 1 1 1 0 Transmembrane protein HATPase_c_3 PF13589.1 EGO56835.1 - 2e-13 50.1 0.0 3.7e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EGO56835.1 - 7.3e-09 35.3 0.0 2.1e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 EGO56835.1 - 0.00026 20.6 0.0 0.00086 18.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2236 PF09995.4 EGO56836.1 - 2.3e-07 30.3 0.6 0.0099 15.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2236) Uds1 PF15456.1 EGO56836.1 - 0.16 11.9 0.8 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 Up-regulated During Septation Fungal_trans PF04082.13 EGO56837.1 - 2.3e-32 111.8 0.0 4.2e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO56837.1 - 2.8e-09 36.7 28.3 2.9e-08 33.4 6.2 2.8 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EGO56837.1 - 3 5.9 47.0 4.9 5.2 32.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C2H2_4 PF13894.1 EGO56840.1 - 0.034 14.4 10.1 0.066 13.5 0.1 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger FYTT PF07078.6 EGO56840.1 - 0.037 13.3 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Forty-two-three protein zf-C2H2 PF00096.21 EGO56840.1 - 0.21 11.9 0.3 0.21 11.9 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EGO56840.1 - 0.99 9.5 4.2 0.65 10.1 0.5 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF1002 PF06207.6 EGO56841.1 - 1.7 7.9 7.6 2.4 7.4 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) p450 PF00067.17 EGO56842.1 - 3.2e-38 131.4 0.0 3.7e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rep_fac_C PF08542.6 EGO56842.1 - 0.11 12.5 0.0 0.45 10.5 0.0 2.0 2 0 0 2 2 2 0 Replication factor C C-terminal domain DUF2985 PF11204.3 EGO56843.1 - 1.1e-28 98.8 4.1 1.9e-28 98.0 2.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) BC10 PF06726.7 EGO56847.1 - 6.8e-18 64.4 10.9 1.2e-17 63.6 7.6 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Y_phosphatase PF00102.22 EGO56852.1 - 2e-55 187.6 0.0 5.1e-32 111.0 0.0 3.4 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.15 EGO56852.1 - 1.4e-11 44.6 0.0 4.4e-11 43.1 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 EGO56852.1 - 0.044 14.0 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 EGO56852.1 - 0.21 11.1 0.5 0.46 10.0 0.3 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain AAA PF00004.24 EGO56853.1 - 5.2e-44 149.6 0.0 8.5e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGO56853.1 - 3.1e-08 33.4 0.0 7.5e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGO56853.1 - 1.2e-07 31.8 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGO56853.1 - 3.3e-06 27.2 0.0 1e-05 25.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO56853.1 - 4.8e-06 26.7 0.1 0.00025 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO56853.1 - 6.1e-05 23.8 0.0 0.00015 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGO56853.1 - 7.6e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGO56853.1 - 0.00014 21.5 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EGO56853.1 - 0.00042 19.7 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EGO56853.1 - 0.00089 18.0 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EGO56853.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGO56853.1 - 0.0017 18.2 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EGO56853.1 - 0.0023 17.5 0.0 0.0074 15.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EGO56853.1 - 0.0024 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EGO56853.1 - 0.0038 17.2 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO56853.1 - 0.0058 16.9 0.0 0.028 14.7 0.0 2.3 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 EGO56853.1 - 0.0068 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EGO56853.1 - 0.0072 15.4 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 EGO56853.1 - 0.017 14.5 0.1 0.081 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 EGO56853.1 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EGO56853.1 - 0.019 14.4 0.0 0.085 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.11 EGO56853.1 - 0.019 14.2 0.0 0.07 12.3 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 EGO56853.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGO56853.1 - 0.028 14.5 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2072 PF09845.4 EGO56853.1 - 0.04 13.8 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Histone PF00125.19 EGO56853.1 - 0.045 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Sigma54_activ_2 PF14532.1 EGO56853.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EGO56853.1 - 0.049 12.5 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EGO56853.1 - 0.076 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 EGO56853.1 - 0.098 12.3 0.0 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Na_Ca_ex PF01699.19 EGO56855.1 - 6.1e-33 113.3 21.1 1.3e-20 73.4 5.3 3.6 5 0 0 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EGO56855.1 - 7e-15 55.1 11.1 7e-15 55.1 7.7 4.0 3 0 0 3 3 3 1 Domain of unknown function (DUF307) DUF1996 PF09362.5 EGO56856.1 - 5.3e-78 261.9 0.9 7.2e-78 261.4 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CorA PF01544.13 EGO56857.1 - 0.01 14.9 10.2 0.17 10.8 7.1 2.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Voltage_CLC PF00654.15 EGO56857.1 - 0.033 13.2 0.7 0.047 12.7 0.5 1.2 1 0 0 1 1 1 0 Voltage gated chloride channel Herpes_UL45 PF05473.7 EGO56857.1 - 0.2 11.0 2.6 0.16 11.3 0.5 1.8 2 0 0 2 2 2 0 UL45 protein Pkinase PF00069.20 EGO56860.1 - 2.4e-20 72.7 0.1 3.9e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO56860.1 - 4.4e-11 42.3 0.1 4.6e-08 32.4 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase DUF2145 PF09916.4 EGO56861.1 - 0.053 13.0 0.0 0.053 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) DUF4311 PF14188.1 EGO56861.1 - 0.074 12.5 0.0 0.074 12.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) Sugar_tr PF00083.19 EGO56862.1 - 2.1e-55 188.0 7.4 1.3e-33 116.2 0.0 3.0 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 EGO56862.1 - 5.9e-18 64.6 12.8 5.4e-09 35.2 2.1 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGO56862.1 - 2.3e-05 22.9 5.1 0.0028 16.1 0.1 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein Phage_holin_2 PF04550.7 EGO56862.1 - 0.036 14.1 1.3 0.41 10.7 0.7 2.4 2 0 0 2 2 2 0 Phage holin family 2 TRI12 PF06609.8 EGO56862.1 - 0.42 8.7 4.3 0.72 7.9 1.0 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Histone PF00125.19 EGO56866.1 - 2.2e-22 78.9 0.1 2.8e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGO56866.1 - 4.8e-05 23.3 0.0 6.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Abhydrolase_6 PF12697.2 EGO56868.1 - 2e-26 93.2 1.5 2.5e-26 93.0 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO56868.1 - 1.2e-11 44.5 0.1 2.2e-11 43.7 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO56868.1 - 1.4e-11 44.3 0.2 1.3e-06 28.1 0.1 2.9 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EGO56868.1 - 2.3e-10 40.1 0.0 4.8e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EGO56868.1 - 0.013 13.9 0.0 0.06 11.8 0.0 1.8 2 0 0 2 2 2 0 Ndr family DUF4182 PF13790.1 EGO56869.1 - 0.0027 17.4 3.0 0.0093 15.7 1.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4182) R3H PF01424.17 EGO56871.1 - 2.1e-10 40.1 0.0 4.6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EGO56871.1 - 2e-07 30.8 0.0 3.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO56871.1 - 3.9e-07 29.6 0.0 6.7e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO56871.1 - 1.8e-05 24.5 0.0 3.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 EGO56871.1 - 0.025 14.5 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Inositol_P PF00459.20 EGO56872.1 - 4.3e-35 121.3 2.0 2.2e-33 115.7 1.4 2.8 1 1 0 1 1 1 1 Inositol monophosphatase family WAPL PF07814.8 EGO56872.1 - 0.2 10.3 0.1 0.29 9.8 0.1 1.2 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin Exo_endo_phos PF03372.18 EGO56874.1 - 8.9e-11 42.1 0.2 1.1e-10 41.9 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EGO56874.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Bac_luciferase PF00296.15 EGO56875.1 - 1.8e-65 221.1 0.9 2.2e-65 220.8 0.6 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase TRF PF08558.5 EGO56877.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) GCR1_C PF12550.3 EGO56880.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes PDDEXK_2 PF12784.2 EGO56886.1 - 0.032 13.3 0.1 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 PD-(D/E)XK nuclease family transposase AAA_4 PF04326.9 EGO56886.1 - 0.053 13.6 0.4 0.054 13.6 0.3 1.1 1 0 0 1 1 1 0 Divergent AAA domain UCN2 PF11613.3 EGO56886.1 - 0.23 11.4 1.1 1.5 8.8 0.1 2.0 2 0 0 2 2 2 0 Agonist of corticotropin releasing factor R2, Urocortin-2 DUF204 PF02659.10 EGO56888.1 - 0.12 12.5 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF Glyco_hydro_61 PF03443.9 EGO56889.1 - 1.8e-52 178.2 1.0 2.1e-52 178.0 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3632 PF12311.3 EGO56890.1 - 2e-39 135.2 2.4 4.1e-39 134.2 1.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) RabGAP-TBC PF00566.13 EGO56891.1 - 4.2e-49 166.9 0.0 7e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3040 PF11239.3 EGO56892.1 - 0.25 11.4 0.6 0.44 10.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) adh_short PF00106.20 EGO56894.1 - 9.1e-31 107.0 0.8 1.2e-30 106.5 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO56894.1 - 9.2e-26 91.0 0.5 1.1e-25 90.7 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO56894.1 - 9.3e-12 44.9 0.7 2.2e-11 43.7 0.5 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO56894.1 - 2.3e-06 27.2 0.3 0.00015 21.3 0.2 3.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EGO56894.1 - 0.064 12.2 0.1 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EGO56894.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Y_phosphatase2 PF03162.8 EGO56895.1 - 2.5e-46 157.0 0.0 3.8e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EGO56895.1 - 7.9e-10 39.2 0.0 1.4e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EGO56895.1 - 0.0032 16.8 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EGO56895.1 - 0.0044 16.6 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF2416 PF10315.4 EGO56896.1 - 0.0013 18.8 1.2 0.0096 16.1 0.2 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2416) DUF1977 PF09320.6 EGO56897.1 - 1.7e-27 95.7 0.2 3.7e-27 94.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EGO56897.1 - 1e-23 82.8 0.5 1.9e-23 81.9 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1836 PF08876.6 EGO56897.1 - 0.13 12.0 1.1 0.71 9.6 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1836) DUF544 PF04424.8 EGO56898.1 - 1.3e-13 50.7 0.0 2.2e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Steroid_dh PF02544.11 EGO56899.1 - 1.7e-21 76.5 2.1 6.1e-20 71.5 1.5 2.4 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DEAD PF00270.24 EGO56899.1 - 9.6e-18 64.2 0.0 1.7e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1295 PF06966.7 EGO56899.1 - 0.0015 17.8 0.2 0.0029 16.9 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ydc2-catalyt PF09159.5 EGO56900.1 - 5.7e-75 252.3 0.3 2.3e-60 204.3 0.0 3.4 1 1 1 2 2 2 2 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EGO56900.1 - 0.0035 17.2 0.0 7.6 6.4 0.0 3.3 3 0 0 3 3 3 1 Poxvirus A22 protein SAP PF02037.22 EGO56900.1 - 0.015 14.7 0.3 0.032 13.7 0.2 1.6 1 0 0 1 1 1 0 SAP domain Pyr_redox_2 PF07992.9 EGO56901.1 - 1.4e-38 132.8 1.4 2.5e-38 132.0 0.9 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EGO56901.1 - 2.5e-33 114.3 0.4 6e-33 113.1 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EGO56901.1 - 9.1e-18 64.4 4.4 6e-17 61.8 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO56901.1 - 6.2e-11 42.7 0.2 2.2e-09 37.6 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO56901.1 - 6.6e-06 25.2 0.1 0.0032 16.4 0.0 2.5 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 EGO56901.1 - 0.00059 19.0 0.3 0.0019 17.3 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 EGO56901.1 - 0.0016 17.4 0.5 0.0029 16.5 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGO56901.1 - 0.0055 15.2 6.3 0.4 9.0 0.0 3.0 2 1 1 3 3 3 2 HI0933-like protein Thi4 PF01946.12 EGO56901.1 - 0.025 13.6 0.2 0.049 12.7 0.2 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EGO56901.1 - 0.1 11.6 5.3 0.65 8.9 0.4 2.7 2 1 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 EGO56901.1 - 0.11 11.2 6.1 2.9 6.6 1.8 2.3 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EGO56901.1 - 1.2 7.8 6.3 1.7 7.4 3.0 2.2 2 1 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EGO56901.1 - 2.6 8.1 5.5 1 9.4 1.6 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EGO56901.1 - 4.4 6.9 5.5 1.3 8.6 0.0 2.7 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain COX7C PF02935.11 EGO56902.1 - 4.1e-11 42.5 1.5 5.4e-11 42.1 1.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Sec6 PF06046.8 EGO56904.1 - 1.7e-157 524.9 14.2 1.2e-155 518.8 9.9 2.1 1 1 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 EGO56904.1 - 0.0021 16.8 2.9 0.0021 16.8 2.0 2.3 3 0 0 3 3 3 1 Vps53-like, N-terminal DUF2450 PF10475.4 EGO56904.1 - 0.015 14.1 3.5 0.054 12.3 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) NPV_P10 PF05531.7 EGO56904.1 - 0.043 14.0 2.0 6 7.1 0.4 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DASH_Duo1 PF08651.5 EGO56904.1 - 0.21 11.1 3.8 0.99 9.0 0.2 3.4 2 1 1 3 3 3 0 DASH complex subunit Duo1 AAA_13 PF13166.1 EGO56904.1 - 0.72 8.2 6.8 0.47 8.8 2.6 2.0 2 1 1 3 3 3 0 AAA domain PPR_2 PF13041.1 EGO56905.1 - 2.5e-14 52.9 0.1 0.00035 20.4 0.0 4.9 4 1 1 5 5 5 4 PPR repeat family PPR PF01535.15 EGO56905.1 - 8.6e-11 41.0 1.9 0.00028 20.6 0.0 5.8 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.1 EGO56905.1 - 4e-10 39.1 5.2 0.19 12.1 0.0 6.1 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 EGO56905.1 - 0.00075 18.9 1.8 1.7 8.1 0.0 4.2 4 0 0 4 4 4 2 PPR repeat MRP-S25 PF13741.1 EGO56906.1 - 8.8e-70 234.7 6.3 2.1e-67 226.9 4.4 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 EGO56906.1 - 0.058 13.2 1.9 0.25 11.2 1.0 2.2 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S23 Alg14 PF08660.6 EGO56907.1 - 3.9e-48 163.6 0.0 5.8e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF1772 PF08592.6 EGO56907.1 - 0.041 13.5 1.4 0.083 12.6 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) PPP5 PF08321.7 EGO56907.1 - 0.14 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 PPP5 TPR repeat region Ima1_N PF09779.4 EGO56908.1 - 7.1e-43 146.2 5.4 1.3e-42 145.4 3.7 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain OrfB_Zn_ribbon PF07282.6 EGO56908.1 - 0.74 9.5 5.9 0.11 12.2 0.5 2.2 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DZR PF12773.2 EGO56908.1 - 2.3 8.1 8.3 0.98 9.2 0.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon DUF2407 PF10302.4 EGO56910.1 - 2.5e-28 98.0 0.0 4.7e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.1 EGO56910.1 - 1.8e-20 73.2 0.0 3.2e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain Rad60-SLD_2 PF13881.1 EGO56910.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ras PF00071.17 EGO56911.1 - 1e-12 47.7 0.0 1.7e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO56911.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Aminotran_1_2 PF00155.16 EGO56912.1 - 2.4e-68 230.7 0.0 2.8e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EGO56912.1 - 3e-05 23.2 0.0 4.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EGO56912.1 - 0.00023 20.4 0.0 0.00035 19.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EGO56912.1 - 0.00098 17.5 0.0 0.0018 16.6 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EGO56912.1 - 0.0068 15.1 0.0 0.014 14.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Aldedh PF00171.17 EGO56913.1 - 3.2e-28 98.3 0.6 3.6e-28 98.1 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGO56913.1 - 0.00061 18.6 0.0 0.00068 18.4 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EGO56913.1 - 0.0067 15.6 0.0 0.0088 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) zf-C2H2_jaz PF12171.3 EGO56913.1 - 1.7 8.9 3.5 3.2 8.0 0.0 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Ald_Xan_dh_C2 PF02738.13 EGO56914.1 - 3.3e-196 652.8 0.6 4.4e-196 652.4 0.4 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EGO56914.1 - 6.8e-47 159.0 0.0 1.3e-46 158.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EGO56914.1 - 1.6e-32 111.4 0.3 1.2e-31 108.7 0.0 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 EGO56914.1 - 3.3e-31 107.6 0.1 8.6e-31 106.2 0.1 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EGO56914.1 - 1.3e-28 98.6 0.0 2.8e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EGO56914.1 - 0.015 15.0 0.9 0.015 15.0 0.6 3.0 2 2 1 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.12 EGO56914.1 - 0.043 13.3 0.2 0.16 11.4 0.1 1.9 2 0 0 2 2 2 0 DUF218 domain SPO22 PF08631.5 EGO56915.1 - 1.7e-84 283.2 3.6 9.5e-84 280.7 0.7 2.6 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 EGO56915.1 - 0.00037 20.3 0.2 0.00037 20.3 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ABC_transp_aux PF09822.4 EGO56915.1 - 0.0063 16.0 0.1 0.081 12.3 0.0 2.2 2 0 0 2 2 2 1 ABC-type uncharacterized transport system TPR_8 PF13181.1 EGO56915.1 - 0.014 15.1 0.1 0.21 11.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGO56915.1 - 0.024 15.0 0.1 16 6.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGO56915.1 - 0.038 13.8 2.7 0.13 12.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGO56915.1 - 0.062 12.9 0.3 0.6 9.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Anti-adapt_IraP PF10796.4 EGO56915.1 - 0.25 11.7 1.9 4.3 7.7 0.0 3.6 3 0 0 3 3 3 0 Sigma-S stabilisation anti-adaptor protein PAS PF00989.19 EGO56916.1 - 0.0037 17.0 0.0 0.086 12.6 0.0 2.4 2 0 0 2 2 2 1 PAS fold HET PF06985.6 EGO56918.1 - 2.8e-26 92.3 7.2 2.8e-26 92.3 5.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) K167R PF08065.7 EGO56918.1 - 0.16 12.1 1.8 0.29 11.2 1.3 1.3 1 0 0 1 1 1 0 K167R (NUC007) repeat Peptidase_C2 PF00648.16 EGO56919.1 - 3.3e-56 190.4 10.6 2.2e-40 138.5 0.4 2.6 3 0 0 3 3 3 2 Calpain family cysteine protease zf-TRAF PF02176.13 EGO56920.1 - 4.7e-10 39.6 37.0 2.4e-06 27.8 8.3 4.1 1 1 3 4 4 4 3 TRAF-type zinc finger zf-RING_2 PF13639.1 EGO56920.1 - 9.3e-07 28.5 8.0 9.3e-07 28.5 5.6 3.7 2 1 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 EGO56920.1 - 1.2e-06 28.1 6.2 1.2e-06 28.1 4.3 3.8 3 1 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGO56920.1 - 1.4e-06 28.1 7.3 1.4e-06 28.1 5.0 3.9 2 1 2 4 4 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO56920.1 - 4.1e-06 26.3 8.3 4.1e-06 26.3 5.8 3.2 3 2 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO56920.1 - 3.2e-05 23.4 4.0 3.2e-05 23.4 2.8 4.1 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGO56920.1 - 0.00023 20.9 7.2 0.00023 20.9 5.0 2.9 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGO56920.1 - 0.0011 18.6 4.6 0.0011 18.6 3.2 2.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EGO56920.1 - 0.0015 18.5 2.4 0.0015 18.5 1.7 2.9 2 1 0 2 2 1 1 RING-H2 zinc finger zf-Di19 PF05605.7 EGO56920.1 - 0.0029 17.7 8.6 0.0029 17.7 5.9 3.8 3 2 1 4 4 3 2 Drought induced 19 protein (Di19), zinc-binding CmcI PF04989.7 EGO56920.1 - 0.16 11.2 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase zf-Nse PF11789.3 EGO56920.1 - 0.91 9.0 21.0 0.018 14.5 7.6 2.8 2 1 1 3 3 2 0 Zinc-finger of the MIZ type in Nse subunit zf-DNA_Pol PF08996.5 EGO56920.1 - 6.9 5.9 20.4 5.4 6.3 6.9 2.5 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger Ufd2P_core PF10408.4 EGO56921.1 - 3.6e-195 649.8 6.1 4.5e-195 649.5 4.3 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EGO56921.1 - 5.6e-26 90.3 1.7 1.5e-25 88.8 1.2 1.8 1 0 0 1 1 1 1 U-box domain Pterin_bind PF00809.17 EGO56921.1 - 0.079 12.3 0.1 2.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Pterin binding enzyme Epimerase PF01370.16 EGO56922.1 - 1.2e-18 67.4 0.0 1.7e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO56922.1 - 1.1e-16 60.3 0.0 1.7e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGO56922.1 - 5.5e-12 45.1 0.0 1.2e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGO56922.1 - 2e-11 44.2 0.9 4.7e-11 43.0 0.6 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGO56922.1 - 4.9e-07 28.9 0.0 9.1e-07 28.0 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EGO56922.1 - 5.5e-07 29.6 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO56922.1 - 6e-05 22.7 0.0 9.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EGO56922.1 - 0.00021 21.6 0.0 0.0006 20.1 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 EGO56922.1 - 0.0021 17.3 0.0 0.031 13.5 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 EGO56922.1 - 0.016 14.0 0.1 0.052 12.4 0.0 1.9 2 1 0 2 2 2 0 RmlD substrate binding domain Saccharop_dh PF03435.13 EGO56922.1 - 0.022 13.7 0.0 0.13 11.2 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase ORC6 PF05460.8 EGO56923.1 - 9.6e-67 225.5 1.2 9.6e-66 222.2 0.0 2.2 2 1 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) Peptidase_M41 PF01434.13 EGO56924.1 - 1.1e-68 230.9 2.0 2.2e-68 229.9 1.4 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EGO56924.1 - 4e-30 104.7 0.0 5e-18 65.5 0.0 2.7 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGO56924.1 - 9.9e-06 26.3 0.0 2.8e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EGO56924.1 - 4.2e-05 22.4 0.0 7.5e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EGO56924.1 - 9.3e-05 22.4 0.1 0.00036 20.5 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EGO56924.1 - 0.00045 19.9 0.4 0.0022 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EGO56924.1 - 0.0011 18.0 0.0 0.0024 16.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EGO56924.1 - 0.0013 18.6 0.1 0.0062 16.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO56924.1 - 0.0014 18.3 0.3 0.0047 16.6 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EGO56924.1 - 0.0027 17.1 1.9 0.0079 15.6 0.2 2.5 3 0 0 3 3 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGO56924.1 - 0.003 16.6 0.0 0.0073 15.4 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EGO56924.1 - 0.0034 16.8 0.4 0.015 14.7 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGO56924.1 - 0.0085 16.2 0.0 0.03 14.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGO56924.1 - 0.013 15.4 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGO56924.1 - 0.014 14.6 0.1 0.034 13.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EGO56924.1 - 0.078 13.2 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain SOG2 PF10428.4 EGO56925.1 - 2.6e-117 392.2 0.0 2.4e-116 389.0 0.0 2.3 2 0 0 2 2 2 1 RAM signalling pathway protein LRR_8 PF13855.1 EGO56925.1 - 1e-16 60.4 0.8 7.7e-09 35.1 0.2 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EGO56925.1 - 2.8e-16 58.7 1.2 5.5e-06 25.8 0.0 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGO56925.1 - 1.2e-08 33.7 2.3 0.9 9.8 0.0 5.7 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EGO56925.1 - 0.00045 19.9 0.3 5 7.7 0.0 4.5 4 0 0 4 4 4 1 Leucine rich repeat HemN_C PF06969.11 EGO56925.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 HemN C-terminal domain LRR_6 PF13516.1 EGO56925.1 - 0.15 12.2 1.9 35 4.9 0.0 4.1 5 0 0 5 5 5 0 Leucine Rich repeat GCN5L1 PF06320.8 EGO56926.1 - 2.5e-06 27.3 0.2 4.1e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Laminin_I PF06008.9 EGO56926.1 - 0.032 13.5 1.0 0.049 12.9 0.7 1.1 1 0 0 1 1 1 0 Laminin Domain I Steroid_dh PF02544.11 EGO56927.1 - 1.4e-19 70.3 0.3 3.4e-19 69.0 0.0 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EGO56927.1 - 0.00027 20.9 1.2 0.00069 19.6 0.0 2.2 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.7 EGO56927.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) rRNA_proc-arch PF13234.1 EGO56928.1 - 4.6e-91 304.6 0.0 1.1e-90 303.5 0.0 1.6 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 EGO56928.1 - 8e-58 194.6 2.0 1.5e-57 193.7 1.4 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EGO56928.1 - 2.3e-21 76.0 0.0 7e-21 74.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO56928.1 - 2.8e-08 33.5 0.0 6.1e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 EGO56928.1 - 0.009 14.9 0.0 0.057 12.3 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein Prp19 PF08606.6 EGO56928.1 - 0.016 14.9 0.5 1.8 8.3 0.1 2.8 2 1 0 2 2 2 0 Prp19/Pso4-like ResIII PF04851.10 EGO56928.1 - 0.038 13.8 1.2 0.15 11.9 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DENN PF02141.16 EGO56929.1 - 1.4e-40 138.9 0.0 2.6e-40 138.1 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EGO56929.1 - 1.5e-05 24.8 0.0 6.9e-05 22.7 0.0 2.3 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 EGO56929.1 - 0.96 9.8 11.8 0.098 13.0 4.2 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A CENP-F_leu_zip PF10473.4 EGO56929.1 - 1.9 8.3 20.1 26 4.6 13.8 2.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 EGO56929.1 - 5.8 6.6 22.2 8.8 6.0 5.3 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DivIVA PF05103.8 EGO56929.1 - 7.6 6.5 23.9 1.4 8.9 5.1 3.3 1 1 2 3 3 3 0 DivIVA protein zf-HIT PF04438.11 EGO56930.1 - 2.1e-10 40.0 8.3 3.1e-10 39.4 5.8 1.3 1 0 0 1 1 1 1 HIT zinc finger LSM14 PF12701.2 EGO56931.1 - 3.3e-26 90.9 0.0 7.4e-26 89.8 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EGO56931.1 - 1.1e-24 86.9 2.0 2.7e-24 85.7 1.4 1.7 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 EGO56931.1 - 0.00084 19.2 0.2 0.0021 17.9 0.0 1.7 2 0 0 2 2 2 1 Ataxin 2 SM domain Tcf25 PF04910.9 EGO56932.1 - 1.2e-76 257.9 0.0 2.3e-76 257.0 0.0 1.5 1 0 0 1 1 1 1 Transcriptional repressor TCF25 NST1 PF13945.1 EGO56932.1 - 0.26 11.3 7.9 0.6 10.1 5.4 1.7 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF2422 PF10337.4 EGO56932.1 - 0.47 9.1 6.1 0.72 8.5 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) HMA PF00403.21 EGO56933.1 - 6.3e-13 48.6 0.3 1.2e-12 47.8 0.2 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF2738 PF10927.3 EGO56933.1 - 0.056 12.4 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) Pirin PF02678.11 EGO56934.1 - 1.3e-31 108.6 0.0 2.9e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EGO56934.1 - 1e-26 92.9 0.1 2.4e-25 88.5 0.1 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EGO56934.1 - 8.5e-10 37.9 4.0 2.1e-05 23.9 0.3 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EGO56934.1 - 0.042 13.2 1.8 0.72 9.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF861) Perilipin PF03036.11 EGO56935.1 - 7.1e-06 25.0 0.0 1.4e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Perilipin family Thiolase_C PF02803.13 EGO56937.1 - 4.3e-11 42.3 0.2 3.2e-10 39.5 0.1 2.5 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EGO56937.1 - 1.1e-07 31.4 0.2 1.2e-05 24.8 0.0 2.9 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EGO56937.1 - 1.8e-05 23.8 0.5 6.6e-05 22.0 0.0 2.2 3 0 0 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EGO56937.1 - 0.0049 16.3 0.2 0.012 15.1 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 EGO56937.1 - 0.0051 15.3 0.4 0.074 11.4 0.1 2.2 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) DUF3328 PF11807.3 EGO56939.1 - 8.8e-53 179.1 0.7 1.2e-52 178.7 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) SPARC_Ca_bdg PF10591.4 EGO56939.1 - 0.0094 15.9 0.1 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region DUF4638 PF15472.1 EGO56940.1 - 0.066 12.7 0.2 0.12 11.9 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4638) NAD_binding_9 PF13454.1 EGO56940.1 - 0.08 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Epimerase PF01370.16 EGO56941.1 - 0.026 13.9 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGO56941.1 - 0.029 13.0 0.0 0.051 12.2 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGO56941.1 - 0.03 14.3 0.0 0.72 9.8 0.0 2.5 1 1 0 1 1 1 0 NADH(P)-binding HET PF06985.6 EGO56942.1 - 1.7e-20 73.6 0.0 3.5e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RasGEF PF00617.14 EGO56943.1 - 4.8e-50 169.9 0.1 7.5e-50 169.2 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGO56943.1 - 1.4e-13 50.7 0.2 3.1e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif DEAD PF00270.24 EGO56945.1 - 5.1e-35 120.4 0.0 3.1e-34 117.9 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO56945.1 - 2e-19 69.2 0.0 4.8e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EGO56945.1 - 2.5e-18 65.3 0.0 4.7e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EGO56945.1 - 0.00032 20.5 4.0 0.0022 17.8 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EGO56945.1 - 0.075 12.7 0.2 1.5 8.6 0.1 3.0 2 1 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 EGO56945.1 - 0.11 12.6 0.1 0.91 9.6 0.1 2.4 1 1 0 1 1 1 0 AAA domain Transformer PF06495.6 EGO56945.1 - 1.5 8.6 7.5 2.8 7.7 5.2 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein DDHD PF02862.12 EGO56945.1 - 2.4 7.9 6.2 3.9 7.2 4.3 1.4 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 EGO56945.1 - 8.6 3.9 15.7 12 3.4 10.9 1.1 1 0 0 1 1 1 0 Ycf1 CTP_transf_1 PF01148.15 EGO56946.1 - 6.2e-15 55.5 12.0 1.1e-11 44.9 3.5 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family DUF2244 PF10003.4 EGO56946.1 - 0.62 9.4 5.0 0.28 10.5 0.9 2.2 1 1 1 2 2 2 0 Integral membrane protein (DUF2244) KxDL PF10241.4 EGO56948.1 - 2.9e-32 110.4 0.4 3.8e-32 110.0 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein GRP PF07172.6 EGO56949.1 - 5.4 7.5 49.2 0.049 14.1 14.0 2.5 3 0 0 3 3 3 0 Glycine rich protein family Cir_N PF10197.4 EGO56950.1 - 0.0015 18.5 2.2 0.0015 18.5 1.5 2.4 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR AAA PF00004.24 EGO56951.1 - 7.3e-51 171.8 0.0 5.3e-39 133.4 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO56951.1 - 2.3e-10 40.6 0.2 0.00045 20.3 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EGO56951.1 - 1.7e-09 37.6 0.0 0.0001 22.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 EGO56951.1 - 6.6e-09 35.2 0.2 1.2e-07 31.1 0.1 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.8 EGO56951.1 - 9.3e-08 31.1 0.0 0.015 14.0 0.0 2.5 2 1 1 3 3 3 2 TIP49 C-terminus AAA_16 PF13191.1 EGO56951.1 - 1.1e-07 32.0 0.0 0.002 18.1 0.0 2.6 3 0 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.1 EGO56951.1 - 1.8e-07 31.9 0.0 0.012 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.13 EGO56951.1 - 5.2e-07 29.5 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_19 PF13245.1 EGO56951.1 - 2.4e-06 27.2 0.8 0.017 14.8 0.0 3.1 3 0 0 3 3 3 2 Part of AAA domain AAA_2 PF07724.9 EGO56951.1 - 2.9e-06 27.2 0.0 9.2e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EGO56951.1 - 3.7e-06 26.8 0.0 0.073 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EGO56951.1 - 7.7e-06 25.4 0.3 0.12 11.8 0.0 2.8 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_5 PF07728.9 EGO56951.1 - 9.1e-06 25.4 0.1 0.0016 18.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EGO56951.1 - 9.2e-06 25.9 0.0 0.032 14.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain Arch_ATPase PF01637.13 EGO56951.1 - 1.9e-05 24.4 0.3 7.2 6.2 0.0 4.4 3 2 2 5 5 5 0 Archaeal ATPase RuvB_N PF05496.7 EGO56951.1 - 7.9e-05 21.8 0.3 0.091 11.7 0.1 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EGO56951.1 - 9.8e-05 21.5 0.7 0.004 16.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EGO56951.1 - 0.00021 21.4 0.0 0.072 13.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 EGO56951.1 - 0.00034 20.3 1.1 0.65 9.6 0.0 3.4 4 0 0 4 4 3 1 NACHT domain AAA_25 PF13481.1 EGO56951.1 - 0.00036 19.9 2.8 0.34 10.2 0.0 3.7 2 2 2 4 4 4 1 AAA domain ABC_tran PF00005.22 EGO56951.1 - 0.00042 20.6 0.1 0.081 13.2 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.21 EGO56951.1 - 0.00048 19.6 0.0 1.1 8.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 EGO56951.1 - 0.0011 18.1 0.1 0.019 14.0 0.1 2.3 2 0 0 2 2 2 1 KaiC AAA_24 PF13479.1 EGO56951.1 - 0.0026 17.3 0.3 0.065 12.8 0.2 2.4 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EGO56951.1 - 0.0026 17.0 0.0 2.2 7.4 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein UPF0079 PF02367.12 EGO56951.1 - 0.0062 16.1 0.1 2.4 7.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EGO56951.1 - 0.0078 15.3 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Parvo_NS1 PF01057.12 EGO56951.1 - 0.0081 15.0 0.0 0.95 8.2 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EGO56951.1 - 0.0088 14.9 0.3 1.2 7.9 0.2 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_28 PF13521.1 EGO56951.1 - 0.01 15.8 0.0 0.78 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EGO56951.1 - 0.013 14.9 0.1 2.5 7.6 0.0 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain CPT PF07931.7 EGO56951.1 - 0.022 14.4 0.0 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_3 PF07726.6 EGO56951.1 - 0.031 13.8 0.0 0.55 9.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EGO56951.1 - 0.064 12.9 0.0 9 5.9 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_30 PF13604.1 EGO56951.1 - 0.091 12.3 0.0 0.79 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EGO56951.1 - 0.16 11.5 0.0 1.2 8.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EGO56951.1 - 0.16 10.9 0.1 0.44 9.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.5 EGO56951.1 - 0.19 10.9 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Band_7 PF01145.20 EGO56952.1 - 6e-26 91.4 4.8 9.3e-26 90.8 3.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EGO56952.1 - 0.063 12.7 0.3 0.1 12.0 0.2 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF3760 PF12586.3 EGO56954.1 - 0.062 13.1 0.5 0.21 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) Ribosomal_S2 PF00318.15 EGO56955.1 - 1e-41 142.4 0.0 3.6e-21 75.3 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 vATP-synt_AC39 PF01992.11 EGO56956.1 - 1.3e-126 422.2 0.0 1.5e-126 422.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.13 EGO56957.1 - 4.5e-53 178.5 0.7 1e-52 177.3 0.5 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGO56957.1 - 2.2e-25 88.2 0.1 4.8e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EGO56957.1 - 7.2e-21 74.1 1.9 7.2e-21 74.1 1.3 2.9 3 1 0 3 3 3 1 NOP5NT (NUC127) domain SPT6_acidic PF14632.1 EGO56957.1 - 0.0095 16.0 13.7 0.0095 16.0 9.5 3.2 2 1 0 2 2 2 1 Acidic N-terminal SPT6 ubiquitin PF00240.18 EGO56958.1 - 4.4e-07 29.2 0.0 5.4e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 EGO56958.1 - 0.019 15.5 0.0 0.022 15.3 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.1 EGO56958.1 - 0.05 13.8 0.0 0.3 11.3 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain Peptidase_S9 PF00326.16 EGO56958.1 - 0.12 11.5 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family TGF_beta_GS PF08515.7 EGO56960.1 - 0.21 10.9 1.5 0.31 10.3 1.0 1.3 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif NST1 PF13945.1 EGO56961.1 - 0.61 10.1 4.0 1.6 8.7 2.7 1.6 1 0 0 1 1 1 0 Salt tolerance down-regulator CBFD_NFYB_HMF PF00808.18 EGO56962.1 - 3.3e-05 23.8 0.1 4.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.9 EGO56962.1 - 0.12 12.1 0.3 0.17 11.7 0.2 1.4 1 1 0 1 1 1 0 hTAFII28-like protein conserved region Prefoldin_2 PF01920.15 EGO56963.1 - 7.4e-24 83.5 9.2 1.1e-23 82.9 6.3 1.3 1 0 0 1 1 1 1 Prefoldin subunit Ecm29 PF13001.2 EGO56963.1 - 0.025 13.1 0.3 0.025 13.1 0.2 1.1 1 0 0 1 1 1 0 Proteasome stabiliser DUF2019 PF09450.5 EGO56963.1 - 0.18 11.6 1.0 0.5 10.2 0.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2019) AAA_23 PF13476.1 EGO56963.1 - 0.29 11.4 12.4 0.41 10.9 8.6 1.2 1 0 0 1 1 1 0 AAA domain Tom37_C PF11801.3 EGO56963.1 - 0.41 10.4 2.8 0.47 10.2 1.9 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain MtrG PF04210.8 EGO56963.1 - 0.56 9.9 5.9 2.9 7.6 0.0 2.5 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G FTA4 PF13093.1 EGO56963.1 - 0.59 9.5 8.8 0.73 9.2 6.1 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Prefoldin PF02996.12 EGO56963.1 - 0.82 9.3 8.7 4.4 6.9 0.8 2.2 1 1 1 2 2 2 0 Prefoldin subunit Lipoprotein_20 PF13942.1 EGO56963.1 - 2.1 7.8 7.5 5.5 6.4 3.4 2.0 2 0 0 2 2 2 0 YfhG lipoprotein DUF4140 PF13600.1 EGO56963.1 - 3.1 8.2 9.3 11 6.5 0.1 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Seryl_tRNA_N PF02403.17 EGO56963.1 - 9.4 6.2 15.2 1.8 8.6 0.3 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MFS_1 PF07690.11 EGO56964.1 - 1e-37 129.7 35.4 1e-37 129.7 24.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO56964.1 - 2.1e-12 46.3 7.6 2.1e-12 46.3 5.2 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Phosphoesterase PF04185.9 EGO56966.1 - 3.1e-23 82.5 0.4 1.4e-22 80.4 0.3 1.8 1 1 0 1 1 1 1 Phosphoesterase family DASH_Dad1 PF08649.5 EGO56967.1 - 5.3e-25 86.8 1.1 7e-25 86.5 0.7 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 WVELL PF14043.1 EGO56967.1 - 0.0021 17.6 0.1 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 WVELL protein GEMIN8 PF15348.1 EGO56967.1 - 0.046 13.7 6.5 0.054 13.5 4.5 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DDHD PF02862.12 EGO56967.1 - 0.37 10.5 7.2 0.38 10.5 5.0 1.1 1 0 0 1 1 1 0 DDHD domain TSA PF03249.8 EGO56967.1 - 0.68 8.4 7.4 0.73 8.3 5.1 1.3 1 0 0 1 1 1 0 Type specific antigen DUF4557 PF15101.1 EGO56967.1 - 0.78 9.5 6.5 0.89 9.3 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Skp1_POZ PF03931.10 EGO56969.1 - 3.1e-12 46.3 0.0 4.9e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 EGO56969.1 - 0.001 19.0 0.0 0.0015 18.4 0.0 1.3 1 1 0 1 1 1 1 BTB/POZ domain Ras PF00071.17 EGO56970.1 - 4.3e-49 165.9 0.0 5.4e-49 165.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO56970.1 - 3.5e-12 46.8 0.0 6.1e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO56970.1 - 1.7e-05 24.1 0.0 4.3e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF2470 PF10615.4 EGO56972.1 - 2.4e-12 46.8 0.6 7.2e-12 45.3 0.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2470) DUF1145 PF06611.7 EGO56972.1 - 0.035 13.7 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1145) DUF1539 PF07560.6 EGO56976.1 - 0.0034 17.2 0.7 0.0046 16.8 0.5 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1539) TipAS PF07739.8 EGO56976.1 - 0.0042 17.4 0.6 1.3 9.3 0.1 2.1 1 1 1 2 2 2 2 TipAS antibiotic-recognition domain DUF3584 PF12128.3 EGO56976.1 - 0.006 13.9 1.1 0.0066 13.8 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Mitofilin PF09731.4 EGO56976.1 - 0.0073 15.0 2.4 0.0086 14.7 1.6 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein RRF PF01765.14 EGO56976.1 - 0.011 15.1 0.8 0.017 14.6 0.6 1.3 1 0 0 1 1 1 0 Ribosome recycling factor TMCO5 PF14992.1 EGO56976.1 - 0.018 14.1 3.2 0.028 13.5 2.2 1.3 1 0 0 1 1 1 0 TMCO5 family PMI_typeI PF01238.16 EGO56976.1 - 0.035 13.0 0.6 0.039 12.9 0.4 1.1 1 0 0 1 1 1 0 Phosphomannose isomerase type I FANCI_S4 PF14678.1 EGO56976.1 - 0.043 12.9 0.4 0.056 12.5 0.3 1.3 1 0 0 1 1 1 0 FANCI solenoid 4 DUF3461 PF11944.3 EGO56976.1 - 0.068 13.0 1.9 0.096 12.5 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) GvpL_GvpF PF06386.6 EGO56976.1 - 0.072 12.6 0.5 0.1 12.1 0.3 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Med30 PF11315.3 EGO56976.1 - 0.074 13.1 0.5 0.091 12.8 0.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 30 FlgN PF05130.7 EGO56976.1 - 0.084 13.1 3.3 0.13 12.5 0.7 1.9 1 1 1 2 2 2 0 FlgN protein DUF4559 PF15112.1 EGO56976.1 - 0.19 10.8 2.9 0.23 10.5 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) IncA PF04156.9 EGO56976.1 - 0.34 10.4 3.4 0.46 10.0 2.4 1.1 1 0 0 1 1 1 0 IncA protein HSCB_C PF07743.8 EGO56976.1 - 0.43 11.0 3.2 1.4 9.4 1.6 2.0 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain FlxA PF14282.1 EGO56976.1 - 8.4 6.3 7.1 10 6.1 1.3 2.2 1 1 1 2 2 2 0 FlxA-like protein Aldedh PF00171.17 EGO56977.1 - 1.5e-189 630.2 0.2 1.6e-189 630.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGO56977.1 - 0.0072 15.0 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) IPI_T4 PF11634.3 EGO56977.1 - 0.089 12.6 0.7 1 9.2 0.1 2.4 2 0 0 2 2 2 0 Nuclease inhibitor from bacteriophage T4 TRF PF08558.5 EGO56978.1 - 1.8e-56 191.1 0.8 2.9e-56 190.4 0.5 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EGO56978.1 - 2.9e-05 24.0 0.0 5.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Fungal_trans PF04082.13 EGO56979.1 - 2.2e-13 49.6 0.4 5.6e-13 48.3 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO56979.1 - 2e-07 30.7 7.6 4.2e-07 29.7 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRF PF06875.6 EGO56979.1 - 0.12 11.5 0.0 0.41 9.8 0.0 1.8 2 0 0 2 2 2 0 Plethodontid receptivity factor PRF zf-H2C2_2 PF13465.1 EGO56983.1 - 7.6e-22 76.4 14.3 3.9e-07 30.0 0.5 4.6 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 EGO56983.1 - 1.4e-16 59.7 26.3 5.5e-05 23.2 1.2 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO56983.1 - 2.1e-05 24.4 30.8 0.028 14.7 1.0 5.0 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO56983.1 - 0.0019 18.2 2.5 2.6 8.2 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Viral_NABP PF05515.6 EGO56983.1 - 0.97 9.7 5.5 1.5 9.1 3.6 1.5 1 1 0 1 1 1 0 Viral nucleic acid binding PAT1 PF09770.4 EGO56983.1 - 1.3 7.2 29.6 1.9 6.6 20.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EF-hand_6 PF13405.1 EGO56985.1 - 8.2e-08 31.5 1.3 0.0044 16.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EGO56985.1 - 8.2e-05 22.6 0.9 8.2e-05 22.6 0.6 2.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EGO56985.1 - 0.00077 18.5 2.3 0.0043 16.2 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EGO56985.1 - 0.011 15.2 1.3 0.05 13.2 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 EGO56985.1 - 0.022 14.1 1.8 0.083 12.2 0.1 2.3 2 0 0 2 2 2 0 EF hand Met_10 PF02475.11 EGO56986.1 - 2e-06 27.5 0.0 3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EGO56986.1 - 0.085 13.4 0.0 0.52 10.8 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain P120R PF08062.6 EGO56987.1 - 0.29 11.4 1.9 0.6 10.4 1.3 1.5 1 0 0 1 1 1 0 P120R (NUC006) repeat Thr_synth_N PF14821.1 EGO56989.1 - 2.6e-28 97.8 0.0 5e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EGO56989.1 - 6.6e-18 64.9 0.0 9e-17 61.2 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DSPc PF00782.15 EGO56991.1 - 5.4e-27 93.9 0.0 1.5e-20 73.1 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGO56991.1 - 0.0004 19.8 0.2 0.0047 16.2 0.2 2.3 2 1 0 2 2 2 1 Protein-tyrosine phosphatase CLU_N PF15044.1 EGO56991.1 - 0.19 11.8 0.1 0.55 10.4 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial function, CLU-N-term CVNH PF08881.5 EGO56993.1 - 1e-41 141.3 1.1 8.9e-26 90.1 0.1 2.4 2 0 0 2 2 2 2 CVNH domain Rootletin PF15035.1 EGO56994.1 - 0.00058 19.8 35.4 0.023 14.6 13.1 2.2 1 1 1 2 2 2 2 Ciliary rootlet component, centrosome cohesion KLRAQ PF10205.4 EGO56994.1 - 0.0013 18.7 21.5 0.002 18.1 6.7 2.5 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein DUF904 PF06005.7 EGO56994.1 - 0.0016 18.7 31.4 0.071 13.4 7.5 4.6 1 1 1 2 2 2 1 Protein of unknown function (DUF904) FlxA PF14282.1 EGO56994.1 - 0.0046 16.8 0.8 0.0046 16.8 0.6 2.9 1 1 1 3 3 3 1 FlxA-like protein GAS PF13851.1 EGO56994.1 - 0.0079 15.4 5.4 0.0079 15.4 3.7 2.3 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.1 EGO56994.1 - 0.029 14.3 5.2 0.029 14.3 3.6 4.0 2 1 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF3121 PF11319.3 EGO56994.1 - 0.03 13.8 2.5 0.16 11.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3121) DUF869 PF05911.6 EGO56994.1 - 0.065 11.4 16.8 0.13 10.5 11.6 1.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF935 PF06074.7 EGO56994.1 - 0.073 11.7 8.0 0.37 9.4 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF935) DivIC PF04977.10 EGO56994.1 - 0.098 12.1 31.5 0.041 13.3 2.0 4.3 2 1 2 4 4 4 0 Septum formation initiator zf-ZPR1 PF03367.8 EGO56994.1 - 0.15 11.1 1.9 0.16 11.1 0.4 1.8 1 1 0 2 2 2 0 ZPR1 zinc-finger domain Reo_sigmaC PF04582.7 EGO56994.1 - 0.16 11.1 0.5 0.65 9.1 0.4 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF724 PF05266.9 EGO56994.1 - 0.16 11.5 15.4 1.2 8.6 3.7 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.4 EGO56994.1 - 0.17 11.7 24.1 0.29 10.9 5.8 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.1 EGO56994.1 - 0.22 10.9 27.0 0.3 10.5 9.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HALZ PF02183.13 EGO56994.1 - 0.37 10.5 30.3 0.23 11.1 2.0 4.9 5 0 0 5 5 5 0 Homeobox associated leucine zipper Acetyltransf_11 PF13720.1 EGO56994.1 - 0.42 10.8 8.6 2.8 8.2 0.2 2.9 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF4047 PF13256.1 EGO56994.1 - 0.44 10.5 7.3 0.32 10.9 2.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) ApoLp-III PF07464.6 EGO56994.1 - 0.98 9.4 11.3 0.35 10.8 3.3 2.7 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) TMF_DNA_bd PF12329.3 EGO56994.1 - 2.4 8.0 24.6 0.51 10.1 8.1 3.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 EGO56994.1 - 3.4 6.5 25.6 0.64 8.9 7.6 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 BLOC1_2 PF10046.4 EGO56994.1 - 3.9 7.6 15.9 0.41 10.8 1.2 3.3 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 EGO56994.1 - 4.1 7.8 22.3 2.6 8.4 4.4 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Tropomyosin_1 PF12718.2 EGO56994.1 - 4.2 7.2 27.2 1.1 9.1 0.8 3.1 1 1 2 3 3 3 0 Tropomyosin like FliD_C PF07195.7 EGO56994.1 - 4.8 6.3 13.2 5.8 6.1 5.9 2.7 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus IncA PF04156.9 EGO56994.1 - 5 6.6 27.7 6.9 6.2 5.5 2.3 1 1 1 2 2 2 0 IncA protein ADIP PF11559.3 EGO56994.1 - 5.3 6.9 31.2 1.9 8.3 11.0 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.7 EGO56994.1 - 5.6 6.7 16.5 2.1 8.0 1.0 2.7 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF342 PF03961.8 EGO56994.1 - 6.1 5.1 12.8 5.8 5.2 7.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Cortex-I_coil PF09304.5 EGO56994.1 - 8.3 6.5 30.6 0.45 10.5 5.0 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil Shugoshin_N PF07558.6 EGO56996.1 - 0.00091 18.8 10.0 0.0031 17.2 5.4 2.4 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Rootletin PF15035.1 EGO56996.1 - 0.01 15.8 20.5 0.01 15.8 14.2 1.8 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Lebercilin PF15619.1 EGO56996.1 - 0.074 12.4 33.0 0.035 13.5 21.3 1.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF972 PF06156.8 EGO56996.1 - 0.89 9.9 26.6 0.14 12.5 9.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Osmo_CC PF08946.5 EGO56996.1 - 0.92 9.5 10.2 0.95 9.5 2.2 2.8 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF4559 PF15112.1 EGO56996.1 - 1 8.4 15.6 1.8 7.6 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) TSC22 PF01166.13 EGO56996.1 - 1.4 8.8 16.0 38 4.3 6.4 3.5 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF342 PF03961.8 EGO56996.1 - 1.6 7.0 11.8 3 6.1 8.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 EGO56996.1 - 3.1 7.3 27.7 4.2 6.9 3.4 3.4 1 1 2 3 3 3 0 Septum formation initiator ADIP PF11559.3 EGO56996.1 - 3.7 7.4 36.1 0.2 11.5 3.2 2.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 EGO56996.1 - 4.1 7.7 36.9 0.034 14.4 9.9 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 EGO56996.1 - 6 4.5 15.8 9 4.0 11.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.4 EGO56996.1 - 9 4.4 23.4 14 3.8 16.2 1.3 1 0 0 1 1 1 0 Transmembrane protein Smg4_UPF3 PF03467.10 EGO56997.1 - 6.2e-50 169.6 0.3 6.2e-50 169.6 0.2 2.5 2 0 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.17 EGO56997.1 - 5.4e-09 35.5 0.7 1.5e-07 30.9 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO56997.1 - 1.1e-07 31.7 0.0 6.1e-06 26.1 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO56997.1 - 0.0031 17.3 0.0 0.0088 15.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 EGO56998.1 - 1.3e-37 129.1 0.0 1.6e-36 125.6 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3070 PF11270.3 EGO56999.1 - 0.082 12.6 0.7 12 5.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3070) Pkinase PF00069.20 EGO57000.1 - 1.5e-06 27.5 0.0 2.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGO57000.1 - 0.0022 17.7 1.1 0.0055 16.4 0.2 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF601 PF04642.7 EGO57000.1 - 0.17 11.2 3.8 0.29 10.4 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 CDC45 PF02724.9 EGO57001.1 - 3.5e-05 22.0 27.5 4.3e-05 21.7 19.0 1.3 1 0 0 1 1 1 1 CDC45-like protein Utp14 PF04615.8 EGO57001.1 - 0.0032 15.7 29.1 0.0033 15.6 20.2 1.1 1 0 0 1 1 1 1 Utp14 protein Mpp10 PF04006.7 EGO57001.1 - 0.0033 15.8 37.9 0.0043 15.5 26.3 1.2 1 0 0 1 1 1 1 Mpp10 protein MIP-T3 PF10243.4 EGO57001.1 - 0.0037 15.8 25.9 0.0043 15.6 18.0 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 EGO57001.1 - 0.0053 14.7 47.7 0.0067 14.4 33.0 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 EGO57001.1 - 0.014 14.7 45.7 0.018 14.3 31.7 1.1 1 0 0 1 1 1 0 SDA1 CENP-T PF15511.1 EGO57001.1 - 0.021 14.0 26.8 0.029 13.6 18.6 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF4045 PF13254.1 EGO57001.1 - 0.026 13.8 13.0 0.03 13.6 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PLRV_ORF5 PF01690.12 EGO57001.1 - 0.17 10.9 18.9 0.19 10.8 13.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Nha1_C PF08619.5 EGO57001.1 - 0.21 10.8 32.5 0.3 10.3 22.5 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Ycf1 PF05758.7 EGO57001.1 - 0.43 8.2 19.5 0.48 8.0 13.5 1.2 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 EGO57001.1 - 0.45 10.3 11.3 0.68 9.7 7.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 EGO57001.1 - 0.58 7.7 25.9 0.72 7.4 18.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.1 EGO57001.1 - 0.72 8.3 16.3 1 7.8 11.3 1.3 1 0 0 1 1 1 0 Raftlin Caldesmon PF02029.10 EGO57001.1 - 1.5 7.1 34.3 1.9 6.8 23.8 1.1 1 0 0 1 1 1 0 Caldesmon Parvo_coat PF00740.13 EGO57001.1 - 1.6 7.5 13.0 2 7.2 9.0 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Merozoite_SPAM PF07133.6 EGO57001.1 - 4.6 7.1 58.2 8 6.3 40.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) TFIIF_alpha PF05793.7 EGO57001.1 - 4.8 5.4 54.6 6.5 4.9 37.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GAGA_bind PF06217.7 EGO57001.1 - 5.5 6.8 13.7 10 6.0 9.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2201_N PF13203.1 EGO57001.1 - 8.5 5.4 24.5 14 4.6 17.0 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain P16-Arc PF04699.9 EGO57007.1 - 2e-59 200.0 0.0 2.4e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Methyltransf_23 PF13489.1 EGO57008.1 - 6.7e-08 32.4 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO57008.1 - 3.3e-07 30.6 0.0 7.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO57008.1 - 6.2e-06 26.6 0.0 1.3e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO57008.1 - 0.0015 18.1 0.0 0.005 16.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO57008.1 - 0.037 14.6 0.0 0.33 11.5 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EGO57008.1 - 0.048 12.7 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Adaptin_N PF01602.15 EGO57009.1 - 4.1e-123 411.4 11.0 5e-123 411.2 7.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EGO57009.1 - 6.9e-48 161.3 0.0 2.7e-47 159.4 0.0 2.0 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EGO57009.1 - 5.1e-20 71.9 0.0 1e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain WD40 PF00400.27 EGO57010.1 - 2e-05 24.3 5.9 0.0021 17.8 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Hira PF07569.6 EGO57010.1 - 0.062 12.5 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split G6PD_bact PF10786.4 EGO57010.1 - 0.2 11.0 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) HET PF06985.6 EGO57012.1 - 3.9e-26 91.8 0.0 6.9e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 2OG-FeII_Oxy_3 PF13640.1 EGO57013.1 - 4.3e-12 46.4 0.1 7.9e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EGO57013.1 - 4.1e-05 23.1 0.0 0.0001 21.8 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4096 PF13340.1 EGO57013.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) DehI PF10778.4 EGO57013.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Halocarboxylic acid dehydrogenase DehI Trehalose_recp PF06151.8 EGO57014.1 - 0.0053 15.1 0.0 0.0072 14.7 0.0 1.1 1 0 0 1 1 1 1 Trehalose receptor MacB_PCD PF12704.2 EGO57014.1 - 0.51 9.8 4.9 1.4 8.4 3.4 1.6 1 1 0 1 1 1 0 MacB-like periplasmic core domain APG6 PF04111.7 EGO57014.1 - 1.9 7.4 4.5 2.7 6.9 3.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 EVI2A PF05399.6 EGO57021.1 - 0.23 10.6 8.9 0.31 10.2 6.2 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF3827 PF12877.2 EGO57021.1 - 0.61 8.1 4.0 0.75 7.8 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Uds1 PF15456.1 EGO57022.1 - 7.9e-39 132.4 10.5 7.9e-39 132.4 7.3 7.7 4 1 0 5 5 5 1 Up-regulated During Septation IncA PF04156.9 EGO57022.1 - 0.016 14.7 88.6 0.026 14.0 8.1 7.1 4 2 3 7 7 7 0 IncA protein Filament PF00038.16 EGO57022.1 - 0.14 11.5 82.9 0.23 10.9 32.4 4.8 4 0 0 4 4 4 0 Intermediate filament protein DUF1751 PF08551.5 EGO57023.1 - 1.2e-06 28.7 0.1 2.1e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EGO57023.1 - 6.5e-05 22.9 3.4 6.5e-05 22.9 2.4 1.7 2 1 0 2 2 2 1 Rhomboid family DER1 PF04511.10 EGO57023.1 - 0.13 11.7 6.3 0.19 11.1 4.4 1.4 1 1 0 1 1 1 0 Der1-like family Gly-zipper_Omp PF13488.1 EGO57023.1 - 0.17 11.5 3.2 0.43 10.2 0.1 2.5 2 0 0 2 2 2 0 Glycine zipper Prenyltransf PF01255.14 EGO57024.1 - 1.4e-95 318.7 0.0 1.8e-95 318.2 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase PHD PF00628.24 EGO57025.1 - 2.3e-10 40.0 6.4 3.9e-10 39.2 4.4 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EGO57025.1 - 2e-07 31.2 0.0 0.00039 20.6 0.0 2.7 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding LRR_6 PF13516.1 EGO57026.1 - 0.002 17.9 0.1 1.2 9.3 0.0 4.0 3 0 0 3 3 3 1 Leucine Rich repeat F-box-like PF12937.2 EGO57026.1 - 0.019 14.6 0.1 0.052 13.2 0.1 1.8 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.2 EGO57026.1 - 0.077 12.6 2.4 0.8 9.3 0.0 3.6 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EGO57026.1 - 7.2 7.2 8.6 41 5.0 0.0 4.9 6 0 0 6 6 6 0 Leucine rich repeat V_ATPase_I PF01496.14 EGO57027.1 - 0 1059.9 0.0 0 1059.7 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.16 EGO57027.1 - 0.0043 16.5 4.9 0.068 12.6 0.5 2.2 2 0 0 2 2 2 2 Intermediate filament protein Baculo_PEP_C PF04513.7 EGO57027.1 - 0.037 13.8 1.8 4.3 7.1 0.5 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 EGO57027.1 - 0.039 12.4 0.8 1.7 6.9 0.2 2.1 2 0 0 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.4 EGO57027.1 - 0.056 13.3 3.5 0.51 10.1 0.1 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.1 EGO57027.1 - 0.06 13.6 2.0 6.6 7.1 0.0 2.9 3 0 0 3 3 3 0 Snapin/Pallidin DUF3584 PF12128.3 EGO57027.1 - 0.13 9.5 4.9 0.19 9.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Prefoldin_2 PF01920.15 EGO57027.1 - 0.16 11.7 3.7 2.6 7.8 0.1 2.7 3 0 0 3 3 3 0 Prefoldin subunit DUF1515 PF07439.6 EGO57027.1 - 0.2 11.4 0.0 0.2 11.4 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) Syntaxin PF00804.20 EGO57027.1 - 2.3 8.4 5.3 1 9.5 0.3 2.6 2 1 0 2 2 2 0 Syntaxin DivIC PF04977.10 EGO57027.1 - 7.8 6.0 8.7 3.7 7.1 0.5 2.9 2 0 0 2 2 2 0 Septum formation initiator Macro PF01661.16 EGO57028.1 - 3.6e-11 43.0 0.0 9.9e-05 22.2 0.0 2.7 2 0 0 2 2 2 2 Macro domain TFIID-18kDa PF02269.11 EGO57029.1 - 1.4e-19 69.6 0.0 2.8e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.1 EGO57029.1 - 4.1e-05 23.6 0.0 9.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EGO57029.1 - 0.00034 20.2 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 EGO57029.1 - 0.014 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Vfa1 PF08432.5 EGO57029.1 - 0.59 10.1 12.8 1 9.3 8.9 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1242 PF06842.7 EGO57030.1 - 2.1e-18 65.4 1.5 2.9e-18 65.0 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1242) Tcp11 PF05794.8 EGO57032.1 - 1.6e-82 277.6 0.0 3e-77 260.2 0.1 2.2 2 0 0 2 2 2 2 T-complex protein 11 DUF2764 PF10962.3 EGO57032.1 - 0.017 14.3 0.2 0.032 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) MFS_1 PF07690.11 EGO57033.1 - 3.9e-36 124.4 66.2 5.9e-29 100.8 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 EGO57034.1 - 1.6e-25 89.9 0.0 2.8e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Endotoxin_mid PF09131.5 EGO57035.1 - 0.049 13.1 0.0 0.094 12.1 0.0 1.4 2 0 0 2 2 2 0 Bacillus thuringiensis delta-Endotoxin, middle domain EamA PF00892.15 EGO57037.1 - 1.9e-18 66.7 18.9 4.6e-15 55.7 2.5 3.4 3 0 0 3 3 3 3 EamA-like transporter family EmrE PF13536.1 EGO57037.1 - 1.2e-06 28.6 5.7 1.2e-06 28.6 4.0 3.7 3 1 1 4 4 4 1 Multidrug resistance efflux transporter FAD_binding_3 PF01494.14 EGO57037.1 - 1.5e-06 27.5 0.2 0.0011 18.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain UAA PF08449.6 EGO57037.1 - 0.16 10.8 1.0 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 UAA transporter family Reo_sigmaC PF04582.7 EGO57038.1 - 0.047 12.8 0.1 0.06 12.5 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EGO57038.1 - 0.056 13.6 1.7 0.11 12.7 1.2 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF904 PF06005.7 EGO57038.1 - 0.27 11.5 6.1 0.34 11.2 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 EGO57038.1 - 4.9 6.7 6.4 0.79 9.2 1.7 1.6 2 0 0 2 2 2 0 Septum formation initiator PNP_UDP_1 PF01048.15 EGO57040.1 - 2.3e-07 30.0 0.1 0.00013 20.9 0.1 3.0 1 1 1 2 2 2 2 Phosphorylase superfamily tRNA_deacylase PF04414.7 EGO57040.1 - 0.038 13.0 1.0 0.67 9.0 0.0 2.2 2 0 0 2 2 2 0 D-aminoacyl-tRNA deacylase TPR_12 PF13424.1 EGO57041.1 - 4.9e-15 55.2 2.4 4.8e-10 39.2 0.0 4.0 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EGO57041.1 - 5.3e-12 45.2 4.2 0.017 15.0 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGO57041.1 - 1.9e-06 28.0 0.3 0.0034 17.6 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGO57041.1 - 6.1e-06 25.7 0.3 0.019 14.6 0.0 4.0 3 0 0 3 3 3 1 TPR repeat NACHT PF05729.7 EGO57041.1 - 5.7e-05 22.8 0.0 0.0002 21.0 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EGO57041.1 - 0.00016 21.8 0.0 0.00042 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain TPR_16 PF13432.1 EGO57041.1 - 0.00025 21.6 0.0 0.32 11.7 0.0 3.4 2 1 1 3 3 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EGO57041.1 - 0.00034 20.6 0.4 0.0088 16.1 0.0 3.0 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGO57041.1 - 0.00035 20.9 0.0 1.4 9.7 0.0 4.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGO57041.1 - 0.00069 19.3 0.9 0.58 10.2 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGO57041.1 - 0.0029 17.1 1.9 4.2 7.1 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO57041.1 - 0.0034 17.0 1.0 5.8 6.9 0.1 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF131 PF01998.12 EGO57041.1 - 0.024 14.0 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF131 TPR_20 PF14561.1 EGO57041.1 - 0.033 14.2 1.9 0.35 11.0 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat AAA_25 PF13481.1 EGO57041.1 - 0.077 12.3 0.1 0.62 9.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain Nucleo_P87 PF07267.6 EGO57043.1 - 0.01 14.5 5.9 0.013 14.2 4.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FAM131 PF15010.1 EGO57043.1 - 0.11 12.2 5.7 0.14 11.8 3.9 1.1 1 0 0 1 1 1 0 Putative cell signalling DUF4611 PF15387.1 EGO57043.1 - 0.18 11.9 13.6 2.1 8.5 6.1 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4611) RRN3 PF05327.6 EGO57043.1 - 0.26 9.3 6.5 0.34 8.9 4.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RXT2_N PF08595.6 EGO57043.1 - 0.3 10.8 3.5 0.49 10.1 2.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF763 PF05559.6 EGO57043.1 - 0.44 9.4 2.5 0.52 9.2 1.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF763) MIF4G_like_2 PF09090.6 EGO57043.1 - 0.55 9.4 3.8 0.74 8.9 2.3 1.4 1 1 0 1 1 1 0 MIF4G like DUF883 PF05957.8 EGO57043.1 - 0.66 10.4 4.4 0.89 9.9 0.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) EzrA PF06160.7 EGO57043.1 - 0.91 7.6 8.3 2.8 6.0 0.4 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Mnd1 PF03962.10 EGO57043.1 - 1.8 8.1 7.0 0.26 10.9 1.3 1.8 1 1 1 2 2 2 0 Mnd1 family DUF506 PF04720.7 EGO57043.1 - 3.6 7.1 6.1 0.54 9.8 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF506) Aegerolysin PF06355.8 EGO57044.1 - 3e-44 150.0 0.0 3.7e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Aegerolysin CPSF73-100_C PF11718.3 EGO57047.1 - 2.8e-79 265.4 0.0 1.7e-75 253.1 0.0 2.2 1 1 1 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EGO57047.1 - 1.1e-31 109.4 0.0 4.4e-31 107.4 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 EGO57047.1 - 7.1e-15 55.1 0.5 1.4e-14 54.1 0.3 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGO57047.1 - 4.5e-13 49.1 0.4 7.7e-13 48.4 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EGO57047.1 - 3.3e-07 30.0 0.3 7e-07 28.9 0.2 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EGO57047.1 - 7.5e-06 25.7 0.1 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TAF4 PF05236.9 EGO57048.1 - 2.3e-10 40.1 0.0 2.3e-10 40.1 0.0 4.8 3 2 1 4 4 4 2 Transcription initiation factor TFIID component TAF4 family IU_nuc_hydro PF01156.14 EGO57049.1 - 4.2e-17 62.3 0.0 1.8e-16 60.2 0.0 1.8 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase HMG_box PF00505.14 EGO57050.1 - 2.3e-21 75.8 1.8 4.9e-21 74.7 1.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO57050.1 - 3.3e-06 27.3 0.3 1.8e-05 25.0 0.3 2.2 2 0 0 2 2 2 1 HMG-box domain BAF1_ABF1 PF04684.8 EGO57050.1 - 0.00023 20.1 11.0 0.00033 19.6 3.4 2.4 2 0 0 2 2 2 2 BAF1 / ABF1 chromatin reorganising factor TIP49 PF06068.8 EGO57051.1 - 1.8e-187 622.9 0.4 2.1e-187 622.7 0.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EGO57051.1 - 4.3e-11 42.3 0.2 3.6e-07 29.4 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EGO57051.1 - 7.5e-11 42.3 0.3 5.8e-07 29.7 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGO57051.1 - 3.1e-05 23.6 0.1 7.1e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EGO57051.1 - 0.00031 20.9 0.3 0.84 9.7 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EGO57051.1 - 0.00035 20.6 0.0 0.082 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EGO57051.1 - 0.00094 18.6 0.0 0.0056 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EGO57051.1 - 0.0019 18.1 0.3 0.0043 17.0 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EGO57051.1 - 0.0042 16.8 0.1 0.099 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EGO57051.1 - 0.0059 15.7 0.4 0.014 14.4 0.3 1.6 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EGO57051.1 - 0.0082 15.3 0.1 0.29 10.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EGO57051.1 - 0.0096 15.3 0.2 0.023 14.1 0.1 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2075 PF09848.4 EGO57051.1 - 0.017 14.1 0.1 0.064 12.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 EGO57051.1 - 0.028 13.3 0.0 0.053 12.3 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Sigma54_activat PF00158.21 EGO57051.1 - 0.03 13.7 0.1 0.74 9.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 EGO57051.1 - 0.032 14.5 0.1 0.081 13.2 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGO57051.1 - 0.063 14.0 0.1 0.18 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EGO57051.1 - 0.45 9.6 3.2 0.49 9.4 0.1 2.4 3 0 0 3 3 3 0 KaiC Dynactin PF12455.3 EGO57052.1 - 1e-94 316.5 3.5 1e-94 316.5 2.4 4.1 4 2 0 5 5 5 1 Dynein associated protein CAP_GLY PF01302.20 EGO57052.1 - 1.6e-24 85.4 0.4 3e-24 84.5 0.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain HET PF06985.6 EGO57053.1 - 1.9e-24 86.3 0.3 4e-24 85.3 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SRP19 PF01922.12 EGO57055.1 - 5.3e-30 103.8 0.0 9.7e-30 103.0 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein Myosin_tail_1 PF01576.14 EGO57056.1 - 0.023 12.4 5.2 0.032 11.9 3.6 1.1 1 0 0 1 1 1 0 Myosin tail CENP-Q PF13094.1 EGO57056.1 - 0.11 12.4 5.1 1.1 9.2 4.8 1.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EGO57056.1 - 1.6 8.3 6.3 2.4 7.7 4.3 1.2 1 0 0 1 1 1 0 IncA protein OMPdecase PF00215.19 EGO57057.1 - 5.6e-99 330.1 0.1 6.9e-99 329.8 0.1 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Fungal_trans PF04082.13 EGO57058.1 - 4.1e-09 35.6 0.0 2.7e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO57058.1 - 4.8e-07 29.5 11.2 8.2e-07 28.8 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arfaptin PF06456.8 EGO57059.1 - 0.13 11.6 2.7 0.23 10.7 1.8 1.3 1 0 0 1 1 1 0 Arfaptin-like domain RRM_1 PF00076.17 EGO57061.1 - 3e-43 145.3 0.9 7.6e-20 70.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO57061.1 - 1.9e-34 117.4 0.2 3.2e-18 65.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EGO57061.1 - 2.2e-30 104.7 0.0 4.9e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EGO57061.1 - 5e-21 74.3 0.0 1.8e-08 34.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGO57061.1 - 0.0014 18.4 0.1 0.089 12.6 0.0 2.7 2 0 0 2 2 2 1 RNA binding motif MIP-T3 PF10243.4 EGO57061.1 - 4.7 5.5 19.6 16 3.7 13.8 1.7 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Cyt-b5 PF00173.23 EGO57062.1 - 6.1e-19 67.5 1.1 2e-18 65.9 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EGO57062.1 - 2.3e-07 31.1 22.8 2.9e-07 30.8 14.4 1.9 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.1 EGO57062.1 - 0.036 13.6 0.6 0.089 12.4 0.2 1.8 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Anth_synt_I_N PF04715.8 EGO57062.1 - 0.072 13.1 1.8 0.094 12.7 0.1 1.9 2 0 0 2 2 2 0 Anthranilate synthase component I, N terminal region Het-C PF07217.6 EGO57063.1 - 7.6e-264 876.5 0.0 1e-263 876.0 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Baculo_PEP_C PF04513.7 EGO57063.1 - 0.24 11.2 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HET PF06985.6 EGO57064.1 - 1.9e-26 92.8 0.0 6e-26 91.2 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PP2C PF00481.16 EGO57065.1 - 8.2e-36 123.6 0.0 3.5e-29 101.9 0.0 3.0 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.1 EGO57065.1 - 0.00057 19.3 0.0 0.0044 16.4 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C BTB PF00651.26 EGO57066.1 - 0.031 14.2 0.0 0.088 12.8 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain FTR1 PF03239.9 EGO57067.1 - 1.7e-72 243.9 9.4 1.6e-48 165.2 5.0 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family NfeD PF01957.13 EGO57067.1 - 0.012 15.7 0.6 0.012 15.7 0.4 3.6 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding DUF3169 PF11368.3 EGO57067.1 - 0.12 11.5 4.1 1.2 8.3 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) Cu-oxidase_3 PF07732.10 EGO57068.1 - 1.2e-44 150.7 3.8 9.1e-42 141.5 0.2 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGO57068.1 - 1.1e-43 148.0 10.0 3.3e-40 136.7 1.2 2.7 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EGO57068.1 - 1.2e-35 122.7 0.7 5.6e-31 107.5 0.1 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EGO57068.1 - 0.00026 20.8 0.0 2.4 8.0 0.0 3.9 4 1 0 4 4 4 2 Cupredoxin-like domain CRA PF06589.6 EGO57068.1 - 0.037 13.3 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) YkyA PF10368.4 EGO57069.1 - 0.063 12.6 10.1 0.034 13.4 5.5 1.5 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein Nucleo_P87 PF07267.6 EGO57069.1 - 0.086 11.5 5.7 0.096 11.3 3.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SpoU_methylase PF00588.14 EGO57069.1 - 0.12 12.2 0.6 0.15 11.9 0.4 1.2 1 0 0 1 1 1 0 SpoU rRNA Methylase family SPOUT_MTase PF02590.12 EGO57069.1 - 0.54 9.9 4.4 0.73 9.5 3.0 1.2 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase SSP160 PF06933.6 EGO57069.1 - 1.9 6.3 3.8 2.1 6.2 2.6 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Spore_III_AF PF09581.5 EGO57069.1 - 7.8 6.3 12.5 0.81 9.5 3.7 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Aminotran_1_2 PF00155.16 EGO57070.1 - 1.3e-36 126.3 0.0 1.6e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGO57070.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase VWA_2 PF13519.1 EGO57071.1 - 1e-08 35.4 0.0 1.1e-06 28.9 0.0 2.6 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EGO57071.1 - 1.7e-06 27.8 0.0 5.7e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EGO57071.1 - 0.0027 17.5 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus PAT1 PF09770.4 EGO57072.1 - 0.0028 16.0 59.2 0.0037 15.6 41.0 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 TAF PF02969.12 EGO57072.1 - 0.014 15.3 0.3 0.03 14.2 0.2 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) HTH_7 PF02796.10 EGO57072.1 - 0.026 14.3 0.0 0.26 11.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase SOBP PF15279.1 EGO57072.1 - 0.17 12.2 26.9 0.28 11.5 18.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Glycos_transf_1 PF00534.15 EGO57073.1 - 1.4e-33 115.7 0.0 3.8e-33 114.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGO57073.1 - 1.1e-08 35.2 0.0 2.8e-07 30.7 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGO57073.1 - 4.8e-07 30.0 0.0 8.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EGO57073.1 - 7.7e-07 28.9 0.0 2e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 EGO57073.1 - 3.6e-05 23.9 0.0 6.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 PAP2 PF01569.16 EGO57074.1 - 1.9e-16 59.8 7.5 1.9e-16 59.8 5.2 1.9 2 0 0 2 2 2 1 PAP2 superfamily JmjC PF02373.17 EGO57075.1 - 2e-35 121.4 0.4 2e-35 121.4 0.3 2.8 3 0 0 3 3 3 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 EGO57075.1 - 1.5e-21 76.4 3.3 3.1e-21 75.4 2.3 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EGO57075.1 - 1.9e-21 75.9 3.2 4.1e-21 74.9 2.2 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 EGO57075.1 - 5.3e-13 48.2 1.0 1.2e-12 47.0 0.7 1.7 1 0 0 1 1 1 1 jmjN domain DUF4440 PF14534.1 EGO57076.1 - 0.0039 17.3 0.0 0.0057 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) HET PF06985.6 EGO57077.1 - 5.3e-16 59.0 0.7 4.6e-08 33.3 0.1 3.2 2 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.6 EGO57078.1 - 2.4e-37 128.1 0.7 4.3e-37 127.3 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Herpes_capsid PF06112.6 EGO57079.1 - 0.28 11.2 5.2 0.46 10.5 3.6 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Beta-lactamase PF00144.19 EGO57079.1 - 1.4 7.8 5.3 5.7 5.8 3.6 1.8 1 1 0 1 1 1 0 Beta-lactamase AA_permease PF00324.16 EGO57080.1 - 4.5e-140 467.1 42.9 5.2e-140 466.9 29.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO57080.1 - 1.2e-34 119.5 48.5 1.6e-34 119.1 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease Defensin_big PF14862.1 EGO57080.1 - 0.053 13.6 0.1 0.16 12.0 0.1 1.8 1 0 0 1 1 1 0 Big defensin Hce2 PF14856.1 EGO57082.1 - 1.3e-27 95.5 0.1 1.7e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor HP_OMP_2 PF02521.9 EGO57082.1 - 0.11 11.0 0.1 0.15 10.6 0.1 1.1 1 0 0 1 1 1 0 Putative outer membrane protein LVIVD PF08309.6 EGO57084.1 - 5.4e-11 41.2 1.1 0.2 10.6 0.0 5.4 5 0 0 5 5 5 5 LVIVD repeat Dicty_REP PF05086.7 EGO57085.1 - 0.16 9.6 0.2 0.22 9.2 0.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LRR_4 PF12799.2 EGO57085.1 - 0.19 11.3 0.1 0.19 11.3 0.1 4.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Septin PF00735.13 EGO57087.1 - 8.1e-114 379.3 1.1 9.7e-114 379.1 0.8 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EGO57087.1 - 7.5e-07 29.1 0.0 1.2e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EGO57087.1 - 1.3e-06 27.6 0.0 2.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EGO57087.1 - 7.4e-06 25.2 0.0 1.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EGO57087.1 - 0.00012 21.6 0.5 0.0045 16.4 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EGO57087.1 - 0.00037 20.3 0.5 0.96 9.2 0.0 2.6 1 1 1 2 2 2 2 Dynamin family AAA_23 PF13476.1 EGO57087.1 - 0.00087 19.6 0.3 0.0013 19.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGO57087.1 - 0.0034 16.8 0.1 0.0037 16.7 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 EGO57087.1 - 0.0044 17.3 0.6 0.0087 16.3 0.3 1.8 1 1 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.7 EGO57087.1 - 0.0073 15.4 0.1 0.035 13.2 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EGO57087.1 - 0.01 15.9 0.0 0.026 14.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGO57087.1 - 0.021 14.3 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.17 EGO57087.1 - 0.028 13.2 0.0 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 EGO57087.1 - 0.028 14.4 0.1 0.075 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 EGO57087.1 - 0.04 12.8 0.1 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Ras PF00071.17 EGO57087.1 - 0.047 13.0 0.1 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Ras family Miro PF08477.8 EGO57087.1 - 0.094 13.2 0.0 0.34 11.4 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein Ribosomal_L32p PF01783.18 EGO57088.1 - 1.9e-13 50.3 5.4 2.8e-13 49.8 3.7 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family RecR PF02132.10 EGO57088.1 - 0.042 13.2 0.3 0.067 12.6 0.2 1.3 1 0 0 1 1 1 0 RecR protein WD40 PF00400.27 EGO57089.1 - 2.5e-23 81.0 8.3 2e-06 27.4 0.2 7.0 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGO57089.1 - 8.9e-05 22.2 0.0 0.0021 17.7 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 EGO57089.1 - 0.0022 17.2 0.1 0.05 12.8 0.0 2.3 2 0 0 2 2 2 1 TUP1-like enhancer of split Nucleoporin_N PF08801.6 EGO57089.1 - 0.0032 16.2 0.0 0.037 12.7 0.0 2.4 2 1 0 2 2 2 1 Nup133 N terminal like Nup160 PF11715.3 EGO57089.1 - 0.015 13.4 0.5 1.8 6.5 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nbas_N PF15492.1 EGO57089.1 - 0.034 13.2 0.0 2.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.1 EGO57089.1 - 0.17 12.1 6.4 0.57 10.5 0.2 3.0 2 0 0 2 2 2 0 PQQ-like domain VWA PF00092.23 EGO57091.1 - 0.043 13.5 0.0 0.056 13.1 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain Pkinase PF00069.20 EGO57095.1 - 2.5e-52 177.5 0.1 2.4e-36 125.2 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57095.1 - 4.5e-22 78.3 0.8 4.3e-20 71.8 0.6 3.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO57095.1 - 7.3e-06 25.1 0.0 2.7e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Kinase-like adh_short PF00106.20 EGO57096.1 - 3.9e-25 88.6 0.8 6.2e-17 62.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EGO57096.1 - 1.5e-13 51.1 0.0 3.3e-13 49.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO57096.1 - 2.1e-07 30.7 0.1 1.1e-06 28.5 0.1 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO57096.1 - 0.0015 18.5 0.1 0.0094 15.9 0.1 2.0 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGO57096.1 - 0.0028 17.1 0.1 0.41 10.0 0.0 2.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family ApbA PF02558.11 EGO57096.1 - 0.016 14.6 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EGO57096.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pex14_N PF04695.8 EGO57096.1 - 0.12 12.4 3.3 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ThiF PF00899.16 EGO57097.1 - 3e-42 143.6 0.2 6.5e-42 142.5 0.1 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EGO57097.1 - 2e-30 104.1 3.1 5.4e-30 102.7 0.3 2.4 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 EGO57097.1 - 2e-23 82.2 0.5 2e-23 82.2 0.4 2.4 3 0 0 3 3 3 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 EGO57097.1 - 9.8e-19 66.4 0.6 9.8e-19 66.4 0.4 2.8 3 0 0 3 3 3 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 EGO57097.1 - 0.0002 21.5 0.4 0.00066 19.8 0.1 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EGO57097.1 - 0.0009 19.3 0.1 0.0022 18.1 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 EGO57097.1 - 0.0059 16.1 0.9 0.096 12.2 0.0 2.6 2 0 0 2 2 2 1 MoeZ/MoeB domain Pyr_redox PF00070.22 EGO57097.1 - 0.0076 16.6 0.1 0.29 11.5 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF2652 PF10851.3 EGO57097.1 - 0.096 12.6 0.3 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2652) DUF2419 PF10343.4 EGO57098.1 - 8.2e-137 455.1 0.0 1e-136 454.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Flexi_CP PF00286.15 EGO57098.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Viral coat protein DNA_pol_delta_4 PF04081.8 EGO57099.1 - 3.5e-49 166.2 0.8 3.5e-49 166.2 0.6 2.4 2 1 0 2 2 1 1 DNA polymerase delta, subunit 4 TFIIF_alpha PF05793.7 EGO57099.1 - 0.015 13.7 18.2 0.02 13.2 12.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mitofilin PF09731.4 EGO57099.1 - 0.031 12.9 15.4 0.032 12.9 10.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein GAGA_bind PF06217.7 EGO57099.1 - 0.19 11.6 15.5 0.26 11.2 10.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Mem_trans PF03547.13 EGO57099.1 - 0.21 9.8 1.7 0.23 9.7 1.2 1.1 1 0 0 1 1 1 0 Membrane transport protein Borrelia_P83 PF05262.6 EGO57099.1 - 0.4 8.8 20.1 0.48 8.6 13.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC27 PF09507.5 EGO57099.1 - 0.54 9.4 28.6 0.67 9.1 19.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.9 EGO57099.1 - 0.86 7.5 9.2 1 7.3 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 EGO57099.1 - 0.97 9.2 19.8 1.5 8.6 13.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FGF-BP1 PF06473.7 EGO57099.1 - 1.4 8.4 15.4 2.7 7.5 10.7 1.5 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF2413 PF10310.4 EGO57099.1 - 1.9 7.2 21.2 2.4 6.8 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Asp-B-Hydro_N PF05279.6 EGO57099.1 - 2.9 7.6 22.1 4.3 7.1 15.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Draxin PF15550.1 EGO57099.1 - 5.4 6.5 15.6 7.3 6.1 10.8 1.1 1 0 0 1 1 1 0 Draxin DUF966 PF06136.8 EGO57099.1 - 7.4 5.8 13.9 9.2 5.5 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) HTH_psq PF05225.11 EGO57100.1 - 2.8e-14 52.3 0.2 5.7e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EGO57100.1 - 4.1e-07 29.7 0.1 0.0011 18.6 0.0 2.4 2 0 0 2 2 2 2 Tc5 transposase DNA-binding domain MSP1_C PF07462.6 EGO57100.1 - 0.012 14.0 5.2 0.018 13.4 3.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Cwf_Cwc_15 PF04889.7 EGO57100.1 - 0.12 12.0 18.0 0.13 11.9 11.8 1.6 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.6 EGO57100.1 - 5.1 6.5 25.9 0.052 13.0 11.1 2.0 2 0 0 2 2 2 0 PPP4R2 Dicty_REP PF05086.7 EGO57100.1 - 7.1 4.2 13.6 15 3.1 9.4 1.5 1 1 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CFEM PF05730.6 EGO57101.1 - 2e-12 46.7 4.6 3.7e-12 45.8 3.2 1.5 1 0 0 1 1 1 1 CFEM domain Nop14 PF04147.7 EGO57102.1 - 0.01 13.8 14.2 0.012 13.5 9.9 1.0 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.10 EGO57102.1 - 0.064 11.8 0.5 0.064 11.8 0.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRAP_alpha PF03896.11 EGO57102.1 - 0.087 11.8 4.8 0.11 11.4 3.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tim54 PF11711.3 EGO57102.1 - 0.099 11.2 4.5 0.12 10.9 3.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 EGO57102.1 - 1.6 6.6 14.2 2 6.3 9.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.6 EGO57102.1 - 3 7.6 17.1 8.1 6.2 11.9 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Vfa1 PF08432.5 EGO57102.1 - 6 6.8 10.5 8.3 6.3 7.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GLTT PF01744.15 EGO57102.1 - 6.2 6.3 6.8 54 3.3 0.1 3.9 4 0 0 4 4 4 0 GLTT repeat (6 copies) BUD22 PF09073.5 EGO57102.1 - 7.1 5.5 16.6 8.9 5.2 11.5 1.0 1 0 0 1 1 1 0 BUD22 HET PF06985.6 EGO57103.1 - 8.9e-36 123.1 0.5 1.7e-35 122.1 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3669 PF12417.3 EGO57104.1 - 6.5e-17 61.0 0.1 3.1e-16 58.8 0.1 2.1 1 1 0 1 1 1 1 Zinc finger protein DUF3669 PF12417.3 EGO57105.1 - 2e-08 33.8 0.1 3.5e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Zinc finger protein Ribonuc_red_lgC PF02867.10 EGO57106.1 - 2.1e-221 736.2 0.0 2.6e-221 735.8 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EGO57106.1 - 2.2e-23 81.8 0.0 5.3e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EGO57106.1 - 1.2e-17 64.1 0.1 1e-16 61.1 0.0 2.5 2 0 0 2 2 2 1 ATP cone domain MMR_HSR1_C PF08438.5 EGO57106.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 GTPase of unknown function C-terminal TatD_DNase PF01026.16 EGO57107.1 - 8e-44 149.7 0.0 3.1e-38 131.4 0.0 2.3 2 1 0 2 2 2 2 TatD related DNase DUF4551 PF15087.1 EGO57107.1 - 3.2 6.0 6.6 4.9 5.3 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RR_TM4-6 PF06459.7 EGO57107.1 - 6.5 6.5 14.9 14 5.4 10.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CENP-N PF05238.8 EGO57108.1 - 3.4e-132 441.2 0.0 1.4e-131 439.2 0.0 1.7 1 1 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.10 EGO57109.1 - 7e-13 48.1 11.6 1.5e-12 47.1 8.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EGO57109.1 - 5.7e-05 22.9 11.6 0.00016 21.5 7.8 1.9 1 1 1 2 2 2 2 bZIP transcription factor XhlA PF10779.4 EGO57109.1 - 0.0027 17.5 2.7 0.0027 17.5 1.9 1.9 2 0 0 2 2 2 1 Haemolysin XhlA TSC22 PF01166.13 EGO57109.1 - 0.035 14.0 0.1 0.086 12.8 0.1 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family IncA PF04156.9 EGO57109.1 - 0.17 11.4 4.1 0.25 10.9 2.9 1.2 1 0 0 1 1 1 0 IncA protein bZIP_Maf PF03131.12 EGO57109.1 - 0.22 11.8 7.7 0.14 12.5 3.8 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor MCC-bdg_PDZ PF10506.4 EGO57109.1 - 0.52 10.1 7.5 0.27 11.1 3.0 2.0 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Ribosomal_60s PF00428.14 EGO57109.1 - 3.3 8.1 20.0 0.11 12.9 8.6 2.3 1 1 1 2 2 2 0 60s Acidic ribosomal protein zf-Nse PF11789.3 EGO57112.1 - 0.0098 15.3 0.1 0.029 13.8 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit ECH PF00378.15 EGO57113.1 - 8.7e-23 80.7 0.0 1.1e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EGO57113.1 - 0.0023 17.7 0.0 1.9 8.2 0.0 2.3 2 1 0 2 2 2 2 Peptidase family S49 ATG27 PF09451.5 EGO57114.1 - 2.2e-98 328.7 0.4 4.1e-98 327.8 0.3 1.4 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EGO57114.1 - 0.00093 18.9 0.1 0.14 11.8 0.0 3.0 3 0 0 3 3 3 1 Cation-independent mannose-6-phosphate receptor repeat Pro-rich PF15240.1 EGO57114.1 - 0.036 14.1 2.1 0.058 13.4 1.5 1.2 1 0 0 1 1 1 0 Proline-rich LRR_4 PF12799.2 EGO57116.1 - 2.3e-35 119.6 22.2 1.3e-08 34.2 1.4 8.4 7 1 0 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO57116.1 - 2.1e-24 85.0 32.2 4.6e-09 35.9 0.4 6.8 6 1 1 7 7 7 5 Leucine rich repeat LRR_1 PF00560.28 EGO57116.1 - 1.1e-11 43.0 33.8 0.11 12.6 0.3 13.0 12 2 1 13 13 13 4 Leucine Rich Repeat LRR_6 PF13516.1 EGO57116.1 - 0.00039 20.1 22.5 8.9 6.7 0.1 9.5 10 0 0 10 10 10 2 Leucine Rich repeat LRR_9 PF14580.1 EGO57116.1 - 0.0037 16.8 6.5 5.2 6.5 0.7 4.3 2 1 2 4 4 4 2 Leucine-rich repeat LRR_7 PF13504.1 EGO57116.1 - 0.0049 16.8 46.5 5.8 7.5 0.3 11.5 13 1 1 14 14 14 4 Leucine rich repeat GerA PF03323.8 EGO57117.1 - 0.12 10.4 1.6 0.12 10.4 1.1 1.0 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Corona_S2 PF01601.11 EGO57117.1 - 0.38 8.8 5.2 0.4 8.7 3.6 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF2873 PF11395.3 EGO57117.1 - 0.85 9.2 8.0 1.2 8.7 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) IPK PF03770.11 EGO57118.1 - 9.1e-56 188.6 0.0 2.2e-55 187.4 0.0 1.7 2 0 0 2 2 2 1 Inositol polyphosphate kinase Pam17 PF08566.5 EGO57118.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Hexapep PF00132.19 EGO57120.1 - 2.2e-09 36.4 0.1 0.002 17.5 0.0 2.7 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EGO57120.1 - 9.1e-05 22.5 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EGO57120.1 - 0.00096 18.5 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EGO57120.1 - 0.012 15.1 5.9 0.18 11.4 1.8 3.2 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase DUF2457 PF10446.4 EGO57120.1 - 1 8.0 18.4 1.7 7.3 12.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) gpUL132 PF11359.3 EGO57122.1 - 0.52 9.6 5.7 0.13 11.6 1.3 1.9 2 0 0 2 2 2 0 Glycoprotein UL132 Spt20 PF12090.3 EGO57123.1 - 4.8e-38 130.3 0.0 4.8e-38 130.3 0.0 8.0 3 2 0 4 4 4 1 Spt20 family HEV_ORF1 PF02444.11 EGO57125.1 - 0.32 11.1 2.7 0.47 10.6 1.8 1.3 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) zf-C2H2_4 PF13894.1 EGO57128.1 - 2.8e-08 33.5 7.5 0.0021 18.2 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO57128.1 - 5.6e-08 32.6 8.6 0.0014 18.8 0.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 EGO57128.1 - 0.0046 17.1 3.6 0.015 15.5 0.0 3.2 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EGO57128.1 - 0.0082 16.3 1.9 0.0082 16.3 1.3 2.9 3 0 0 3 3 3 1 Zinc-finger double domain DUF4408 PF14364.1 EGO57129.1 - 0.039 13.5 0.3 0.09 12.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4408) LRR_4 PF12799.2 EGO57130.1 - 0.0029 17.2 1.6 1.2 8.8 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EGO57130.1 - 0.12 12.5 4.7 0.5 10.5 0.0 3.3 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.28 EGO57130.1 - 0.25 11.5 2.0 13 6.2 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat Col_cuticle_N PF01484.12 EGO57131.1 - 5.2 6.8 4.7 11 5.7 3.3 1.5 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Abp2 PF09441.5 EGO57132.1 - 1.1e-90 302.2 0.0 1.8e-90 301.5 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 Mito_carr PF00153.22 EGO57133.1 - 5.9e-54 179.7 2.7 8.9e-17 60.5 0.3 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EGO57133.1 - 0.0015 18.3 0.1 0.0037 17.0 0.1 1.8 1 0 0 1 1 1 1 UcrQ family Mak10 PF04112.8 EGO57134.1 - 1.5e-54 183.7 0.0 2.5e-54 182.9 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.8 EGO57135.1 - 1.1e-21 76.1 3.0 1.1e-21 76.1 2.1 1.4 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16 PF00675.15 EGO57136.1 - 2.5e-19 69.5 0.0 3.6e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGO57136.1 - 6e-14 52.1 0.0 1.8e-13 50.6 0.0 1.8 3 0 0 3 3 3 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.8 EGO57137.1 - 1.2e-70 238.0 3.3 5.6e-70 235.8 0.2 3.1 4 0 0 4 4 4 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EGO57137.1 - 3.4e-22 78.0 1.0 8.4e-21 73.6 0.4 3.2 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TrmB PF01978.14 EGO57137.1 - 0.0047 16.5 0.5 0.61 9.8 0.0 3.3 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB PBP1_TM PF14812.1 EGO57137.1 - 0.42 10.9 6.3 0.067 13.4 0.9 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mito_carr PF00153.22 EGO57138.1 - 6.5e-32 109.1 0.4 4.8e-14 51.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SRP-alpha_N PF04086.8 EGO57139.1 - 0.0052 16.2 32.3 0.0085 15.5 22.4 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal DUF1510 PF07423.6 EGO57139.1 - 0.0063 15.8 30.6 0.0063 15.8 21.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) UPF0565 PF10561.4 EGO57139.1 - 0.078 11.8 11.3 0.083 11.7 7.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF2052 PF09747.4 EGO57139.1 - 0.16 11.8 16.0 0.17 11.7 11.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF2828 PF11443.3 EGO57139.1 - 0.17 10.0 22.1 0.21 9.7 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) IncFII_repA PF02387.10 EGO57139.1 - 0.22 10.6 32.6 0.24 10.5 22.6 1.0 1 0 0 1 1 1 0 IncFII RepA protein family Serinc PF03348.10 EGO57139.1 - 0.3 9.7 10.0 0.41 9.3 6.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.7 EGO57139.1 - 0.32 10.8 31.1 0.38 10.6 21.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.3 EGO57139.1 - 0.39 9.9 22.6 0.45 9.8 15.7 1.0 1 0 0 1 1 1 0 SprA-related family DUF2413 PF10310.4 EGO57139.1 - 0.43 9.3 36.0 0.47 9.2 24.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Kei1 PF08552.6 EGO57139.1 - 0.44 10.1 3.7 0.61 9.7 2.6 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Tim54 PF11711.3 EGO57139.1 - 0.45 9.0 22.6 0.55 8.7 15.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DHHW PF14286.1 EGO57139.1 - 0.75 9.0 13.9 0.82 8.9 9.6 1.0 1 0 0 1 1 1 0 DHHW protein DDHD PF02862.12 EGO57139.1 - 0.81 9.4 21.4 1 9.1 14.8 1.2 1 0 0 1 1 1 0 DDHD domain Mem_trans PF03547.13 EGO57139.1 - 1.4 7.1 7.2 1.5 7.0 5.0 1.0 1 0 0 1 1 1 0 Membrane transport protein RP-C_C PF11800.3 EGO57139.1 - 1.6 8.3 16.5 1.9 8.1 11.4 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Gag_spuma PF03276.9 EGO57139.1 - 1.7 6.9 9.0 1.6 6.9 6.2 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Zip PF02535.17 EGO57139.1 - 2.2 7.1 11.9 2.6 6.9 8.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Abi_2 PF07751.6 EGO57139.1 - 4.5 7.4 19.6 5.5 7.1 13.6 1.0 1 0 0 1 1 1 0 Abi-like protein DUF3260 PF11658.3 EGO57139.1 - 5.2 5.0 6.9 6.1 4.8 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Peptidase_U57 PF05582.7 EGO57139.1 - 6.8 5.5 19.4 11 4.9 13.4 1.4 1 0 0 1 1 1 0 YabG peptidase U57 eIF-3_zeta PF05091.7 EGO57139.1 - 7.7 5.0 24.6 8.1 4.9 17.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.11 EGO57139.1 - 9.8 5.9 19.3 10 5.8 13.4 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Actin PF00022.14 EGO57141.1 - 3.2e-20 71.9 0.0 6.7e-18 64.2 0.0 3.3 2 1 0 2 2 2 2 Actin XPG_I PF00867.13 EGO57142.1 - 2.2e-25 88.5 0.0 4.8e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EGO57142.1 - 3.6e-07 30.3 0.0 7.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain KOW PF00467.24 EGO57143.1 - 6.5e-07 28.8 2.8 1.2e-06 27.9 1.2 2.0 2 0 0 2 2 2 1 KOW motif adh_short PF00106.20 EGO57144.1 - 9.9e-23 80.8 0.0 1.4e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO57144.1 - 8.3e-07 29.0 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO57144.1 - 4.4e-05 23.2 0.1 0.00012 21.7 0.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO57144.1 - 0.0012 18.2 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO57144.1 - 0.014 15.4 0.0 0.055 13.4 0.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding APC_CDC26 PF10471.4 EGO57147.1 - 0.11 13.2 0.4 0.11 13.2 0.3 3.7 3 2 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Pkinase PF00069.20 EGO57148.1 - 4.5e-70 235.7 0.0 6.1e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57148.1 - 3.1e-37 128.0 0.0 5.1e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO57148.1 - 1.5e-06 27.3 0.0 9.1e-05 21.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGO57148.1 - 0.00079 18.5 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO57148.1 - 0.003 17.3 1.3 0.009 15.7 0.0 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family SWIB PF02201.13 EGO57149.1 - 1.7e-10 40.4 0.0 3.3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain Sfi1 PF08457.5 EGO57150.1 - 8.5e-172 572.5 67.4 3.8e-170 567.0 42.1 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein CHCH PF06747.8 EGO57151.1 - 0.036 13.9 2.5 0.59 10.1 1.8 2.1 1 1 1 2 2 2 0 CHCH domain Cmc1 PF08583.5 EGO57151.1 - 0.047 13.4 0.5 0.073 12.8 0.4 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 EGO57151.1 - 0.053 13.4 0.9 0.077 12.9 0.6 1.3 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein tRNA-synt_1 PF00133.17 EGO57152.1 - 1.3e-225 750.0 0.1 2e-225 749.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGO57152.1 - 3.2e-26 91.9 0.0 9.2e-26 90.4 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGO57152.1 - 2.1e-19 69.4 0.2 1e-07 30.9 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EGO57152.1 - 0.031 13.4 0.0 0.092 11.8 0.0 1.8 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Mo25 PF08569.6 EGO57153.1 - 3.7e-127 423.9 0.1 4.2e-127 423.8 0.0 1.0 1 0 0 1 1 1 1 Mo25-like GAT PF03127.9 EGO57153.1 - 0.056 13.4 0.5 8.9 6.3 0.0 2.8 2 0 0 2 2 2 0 GAT domain NUDIX-like PF09296.6 EGO57154.1 - 0.0089 16.3 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Ala_racemase_N PF01168.15 EGO57156.1 - 1.1e-39 136.2 0.0 1.3e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Synaptobrevin PF00957.16 EGO57157.1 - 0.1 12.1 0.4 0.23 11.1 0.3 1.5 1 0 0 1 1 1 0 Synaptobrevin NAS PF03059.11 EGO57160.1 - 0.0055 15.8 0.5 0.11 11.6 0.1 2.1 2 0 0 2 2 2 2 Nicotianamine synthase protein HTH_Tnp_IS630 PF01710.11 EGO57160.1 - 0.84 9.3 9.1 0.73 9.5 4.9 1.8 2 0 0 2 2 2 0 Transposase tRNA-synt_2b PF00587.20 EGO57161.1 - 1e-17 64.2 0.0 1.5e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EGO57161.1 - 1.6e-10 40.9 5.5 1.2e-09 38.1 3.8 2.1 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Prp19 PF08606.6 EGO57161.1 - 0.08 12.6 0.8 0.4 10.4 0.4 2.4 2 1 0 2 2 2 0 Prp19/Pso4-like MS_channel PF00924.13 EGO57162.1 - 3.8e-21 75.3 2.9 6.5e-21 74.6 2.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EGO57162.1 - 0.0046 16.1 0.2 0.011 14.9 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EGO57162.1 - 0.0068 15.7 0.1 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EGO57162.1 - 0.015 15.1 0.1 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.1 EGO57162.1 - 0.018 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair ODV-E18 PF10717.4 EGO57162.1 - 0.1 12.0 0.8 0.41 10.1 0.5 2.0 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Vma12 PF11712.3 EGO57162.1 - 4.1 7.1 10.8 3.1 7.5 2.2 2.7 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PhyH PF05721.8 EGO57163.1 - 4.3e-13 49.7 0.0 5.5e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF342 PF03961.8 EGO57164.1 - 0.016 13.6 10.6 0.016 13.6 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) VSG_B PF13206.1 EGO57164.1 - 0.019 14.0 12.5 0.023 13.8 8.6 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain Muted PF14942.1 EGO57164.1 - 0.038 13.8 13.9 0.047 13.5 9.7 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein ERM PF00769.14 EGO57164.1 - 0.052 13.0 22.9 0.064 12.7 15.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TMEM247 PF15444.1 EGO57164.1 - 0.1 12.4 7.5 0.11 12.2 5.2 1.0 1 0 0 1 1 1 0 Transmembrane protein 247 Fmp27_WPPW PF10359.4 EGO57164.1 - 0.13 10.7 12.0 0.15 10.4 8.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4121 PF13497.1 EGO57164.1 - 0.34 9.8 5.5 0.22 10.4 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4121) DUF3527 PF12043.3 EGO57164.1 - 0.48 9.8 6.2 0.57 9.6 4.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) eIF3_N PF09440.5 EGO57164.1 - 0.53 10.4 9.6 0.65 10.1 6.6 1.2 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain Pilt PF15453.1 EGO57164.1 - 0.77 9.3 9.3 0.89 9.1 6.5 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions AbiH PF14253.1 EGO57164.1 - 0.87 9.1 7.0 1 8.9 4.8 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH V_ATPase_I PF01496.14 EGO57164.1 - 0.9 7.3 11.4 1 7.1 7.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4559 PF15112.1 EGO57164.1 - 0.97 8.5 11.2 0.26 10.4 4.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) DUF3810 PF12725.2 EGO57164.1 - 1.3 7.8 5.5 1.5 7.6 3.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3417 PF11897.3 EGO57164.1 - 1.4 8.8 6.0 2.6 8.0 4.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3417) IncA PF04156.9 EGO57164.1 - 1.5 8.4 13.1 2 7.9 9.1 1.2 1 0 0 1 1 1 0 IncA protein POX PF07526.6 EGO57164.1 - 1.5 9.0 9.9 1.9 8.7 6.8 1.1 1 0 0 1 1 1 0 Associated with HOX ISG65-75 PF11727.3 EGO57164.1 - 1.5 7.7 16.1 1.9 7.4 11.1 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF2968 PF11180.3 EGO57164.1 - 1.6 8.0 12.2 2 7.7 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Neur_chan_memb PF02932.11 EGO57164.1 - 2.6 7.8 4.8 3 7.6 3.3 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1510 PF07423.6 EGO57164.1 - 3 7.1 18.6 3.7 6.8 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_pol_Rpb1_1 PF04997.7 EGO57164.1 - 3.6 6.7 11.1 4.1 6.5 7.7 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Atg14 PF10186.4 EGO57164.1 - 3.6 6.4 13.0 4.3 6.2 9.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin PF00804.20 EGO57164.1 - 4 7.6 15.8 6.1 7.0 11.0 1.3 1 1 0 1 1 1 0 Syntaxin hDGE_amylase PF14701.1 EGO57164.1 - 4.2 6.1 7.2 5 5.9 5.0 1.0 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme APG6 PF04111.7 EGO57164.1 - 4.5 6.2 18.1 5.8 5.8 12.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 EGO57164.1 - 4.7 5.5 16.0 6.3 5.1 11.1 1.2 1 0 0 1 1 1 0 AAA domain GBP_C PF02841.9 EGO57164.1 - 4.8 6.2 20.5 6.7 5.8 14.2 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Med8 PF10232.4 EGO57164.1 - 5 6.5 13.4 5.8 6.3 9.3 1.0 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 CDC45 PF02724.9 EGO57164.1 - 5.3 4.9 12.9 6.3 4.7 9.0 1.0 1 0 0 1 1 1 0 CDC45-like protein D5_N PF08706.6 EGO57164.1 - 5.3 7.1 9.0 6.5 6.8 6.3 1.2 1 0 0 1 1 1 0 D5 N terminal like BTV_NS2 PF04514.7 EGO57164.1 - 5.8 5.7 17.4 7.2 5.3 12.1 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 EMP24_GP25L PF01105.19 EGO57164.1 - 6.3 6.4 7.2 8.3 6.0 5.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Spore_coat_CotO PF14153.1 EGO57164.1 - 6.5 6.1 19.4 9.8 5.5 13.4 1.3 1 0 0 1 1 1 0 Spore coat protein CotO HAUS6_N PF14661.1 EGO57164.1 - 8.9 5.5 16.0 11 5.2 11.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DDHD PF02862.12 EGO57164.1 - 9.8 5.8 9.6 14 5.4 6.6 1.2 1 0 0 1 1 1 0 DDHD domain RNA12 PF10443.4 EGO57166.1 - 2.3e-169 563.4 1.7 3.1e-169 563.0 1.1 1.1 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.17 EGO57166.1 - 1.5e-09 37.3 0.0 3.5e-06 26.5 0.0 3.4 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO57166.1 - 1.4e-05 24.8 0.0 9.1e-05 22.2 0.0 2.3 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO57166.1 - 5.6e-05 23.0 0.0 0.032 14.2 0.0 3.2 2 1 1 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 EGO57166.1 - 0.0011 18.7 0.1 0.17 11.5 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase DUF2487 PF10673.4 EGO57166.1 - 0.0026 17.5 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) AAA_16 PF13191.1 EGO57166.1 - 0.034 14.1 0.1 0.12 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EGO57166.1 - 0.062 13.4 0.1 2.6 8.2 0.0 2.8 1 1 0 1 1 1 0 AAA domain DUF3128 PF11326.3 EGO57167.1 - 1.5e-30 105.1 1.8 2.5e-30 104.4 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DLH PF01738.13 EGO57168.1 - 5.4e-21 74.8 0.0 3.8e-20 72.1 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGO57168.1 - 7e-06 25.8 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO57168.1 - 0.00044 20.2 0.5 0.0021 17.9 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EGO57168.1 - 0.0011 18.4 0.0 0.0025 17.2 0.0 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 EGO57168.1 - 0.017 14.8 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 EGO57168.1 - 0.13 10.7 0.0 0.21 10.0 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) HSP70 PF00012.15 EGO57169.1 - 7.4e-273 905.9 5.4 8.4e-273 905.7 3.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGO57169.1 - 3.8e-18 65.1 0.1 7.1e-17 60.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EGO57169.1 - 0.0011 18.6 0.0 0.003 17.2 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EGO57169.1 - 0.008 15.3 0.0 0.039 13.0 0.0 2.0 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.1 EGO57169.1 - 0.044 13.6 1.8 3.9 7.3 0.1 3.1 2 2 0 2 2 2 0 Cell division protein FtsA StbA PF06406.6 EGO57169.1 - 0.045 12.6 0.0 0.089 11.7 0.0 1.4 1 0 0 1 1 1 0 StbA protein DUF4404 PF14357.1 EGO57169.1 - 1.9 8.9 7.9 1.7 9.0 1.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF489 PF04356.7 EGO57172.1 - 0.037 13.6 2.5 0.059 12.9 1.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF489) Kinetocho_Slk19 PF12709.2 EGO57172.1 - 0.059 13.4 5.1 0.12 12.4 3.6 1.6 1 0 0 1 1 1 0 Central kinetochore-associated FUSC PF04632.7 EGO57172.1 - 0.062 11.7 2.9 0.07 11.5 2.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Acetyltransf_6 PF13480.1 EGO57172.1 - 0.078 12.9 2.5 0.11 12.4 1.7 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GAS PF13851.1 EGO57172.1 - 0.15 11.2 9.3 0.14 11.3 5.7 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EGO57172.1 - 0.44 9.5 7.2 0.57 9.1 5.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF572 PF04502.8 EGO57172.1 - 1.3 8.2 7.8 1.4 8.0 5.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) OmpH PF03938.9 EGO57172.1 - 4.6 7.1 9.1 6.2 6.7 6.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1789 PF08748.6 EGO57172.1 - 9.6 6.3 8.7 64 3.6 6.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1789) RNase_HII PF01351.13 EGO57175.1 - 4.4e-48 163.5 0.1 6e-43 146.8 0.0 2.1 2 0 0 2 2 2 2 Ribonuclease HII DUF3323 PF11796.3 EGO57175.1 - 0.061 12.6 0.1 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Mif2_N PF15624.1 EGO57176.1 - 2.1e-36 125.5 3.1 2.1e-36 125.5 2.2 3.9 2 1 1 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 EGO57176.1 - 1.4e-33 114.7 0.4 2.1e-33 114.1 0.3 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 EGO57176.1 - 9.6e-07 28.2 0.0 1.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EGO57176.1 - 0.089 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Cupin RHD3 PF05879.7 EGO57177.1 - 0 1134.7 0.0 0 1134.5 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EGO57177.1 - 5.3e-09 35.5 0.2 8.4e-09 34.8 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EGO57177.1 - 1.1e-06 28.5 0.0 2.5e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EGO57177.1 - 6.6e-05 22.8 0.0 0.00021 21.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EGO57177.1 - 0.00065 20.1 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EGO57177.1 - 0.00094 19.1 0.1 0.0038 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Septin PF00735.13 EGO57177.1 - 0.073 12.0 0.1 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Septin Fructosamin_kin PF03881.9 EGO57178.1 - 2.8e-30 105.3 0.0 3e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase RE_MjaI PF09568.5 EGO57178.1 - 0.0011 18.4 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 MjaI restriction endonuclease EcKinase PF02958.15 EGO57178.1 - 0.0065 15.6 0.0 0.0082 15.3 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EGO57178.1 - 0.011 14.3 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) APH PF01636.18 EGO57178.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans_2 PF11951.3 EGO57179.1 - 7.4e-10 37.9 0.2 1.1e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO57179.1 - 1.4e-06 28.0 13.6 2.5e-06 27.2 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 EGO57179.1 - 0.25 10.8 5.0 0.5 9.9 3.5 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Med18 PF09637.5 EGO57180.1 - 8.8e-51 172.8 0.0 9.9e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Med18 protein Borealin PF10512.4 EGO57181.1 - 0.5 10.3 5.4 0.98 9.3 0.0 2.4 2 0 0 2 2 2 0 Cell division cycle-associated protein 8 Amidohydro_1 PF01979.15 EGO57183.1 - 1.4e-34 120.2 0.0 1.9e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EGO57183.1 - 1.1e-07 31.4 0.1 8.7e-05 21.8 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 EGO57183.1 - 2.4e-07 31.0 0.3 0.0009 19.3 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase A_deaminase PF00962.17 EGO57183.1 - 0.00012 21.1 0.0 0.0002 20.3 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_5 PF13594.1 EGO57183.1 - 0.00013 21.7 0.1 0.00034 20.3 0.1 1.8 1 0 0 1 1 1 1 Amidohydrolase TPR_12 PF13424.1 EGO57186.1 - 1.2e-10 41.2 0.0 0.00034 20.4 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGO57186.1 - 5.2e-07 29.3 0.6 0.2 11.6 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGO57186.1 - 8.8e-06 25.9 0.8 0.39 11.4 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGO57186.1 - 0.0044 16.7 0.3 2.3 8.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGO57186.1 - 0.0054 16.2 0.0 1.2 8.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.4 EGO57186.1 - 0.0092 15.3 0.0 2.2 7.6 0.0 2.5 2 0 0 2 2 2 2 26S proteasome subunit RPN7 TPR_4 PF07721.9 EGO57186.1 - 0.01 16.1 0.7 4.4 8.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Clr5 PF14420.1 EGO57186.1 - 0.012 15.4 0.2 0.046 13.6 0.1 2.0 1 0 0 1 1 1 0 Clr5 domain TPR_16 PF13432.1 EGO57186.1 - 0.012 16.2 0.2 0.39 11.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGO57186.1 - 0.024 14.5 0.0 0.94 9.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Clr5 PF14420.1 EGO57187.1 - 1.4e-09 37.6 0.0 2.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Clr5 domain DUF2516 PF10724.4 EGO57188.1 - 0.53 10.3 2.5 0.88 9.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2516) IncA PF04156.9 EGO57188.1 - 5.1 6.6 11.0 1.5 8.4 0.2 3.1 3 0 0 3 3 3 0 IncA protein HET PF06985.6 EGO57190.1 - 1.3e-19 70.7 0.0 2.6e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2945 PF11160.3 EGO57191.1 - 3.9e-24 84.2 0.2 4.4e-24 84.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) PhoD PF09423.5 EGO57192.1 - 2.6e-115 385.5 1.6 3.3e-115 385.2 1.1 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase UPRTase PF14681.1 EGO57194.1 - 7.5e-29 100.4 0.9 2.1e-28 98.9 0.0 2.0 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase HAD PF12710.2 EGO57194.1 - 2.6e-09 37.5 0.0 6.4e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.1 EGO57194.1 - 2.7e-06 28.1 0.0 9.8e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO57194.1 - 0.00024 21.4 0.0 0.00089 19.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain Hydrolase PF00702.21 EGO57194.1 - 0.00026 21.4 0.1 0.0012 19.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_28 PF13521.1 EGO57194.1 - 0.00066 19.6 0.4 0.0021 18.0 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGO57194.1 - 0.00098 19.0 0.2 0.0033 17.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EGO57194.1 - 0.0018 17.3 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Zeta_toxin PF06414.7 EGO57194.1 - 0.0066 15.5 0.3 0.086 11.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ArgK PF03308.11 EGO57194.1 - 0.0069 15.2 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 ArgK protein Pribosyltran PF00156.22 EGO57194.1 - 0.0073 16.0 0.3 0.21 11.3 0.2 2.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain AAA_5 PF07728.9 EGO57194.1 - 0.0082 15.8 0.1 0.14 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGO57194.1 - 0.016 15.2 0.0 0.059 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EGO57194.1 - 0.039 14.2 0.1 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Hydrolase_3 PF08282.7 EGO57194.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MMR_HSR1 PF01926.18 EGO57194.1 - 0.057 13.3 0.0 0.21 11.5 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 EGO57194.1 - 0.067 13.3 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EGO57194.1 - 0.079 12.4 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EGO57194.1 - 0.086 12.4 0.1 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EGO57194.1 - 0.12 11.7 3.2 7.9 5.8 0.0 3.9 4 0 0 4 4 4 0 AAA domain Asp PF00026.18 EGO57195.1 - 2.3e-52 178.2 1.9 3e-52 177.8 1.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO57195.1 - 7.1e-09 35.8 0.6 7.1e-09 35.8 0.4 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO57195.1 - 0.02 15.3 0.1 0.81 10.2 0.0 3.2 4 0 0 4 4 4 0 Aspartyl protease NUDIX PF00293.23 EGO57196.1 - 1.2e-10 41.1 0.0 1.9e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain DUF3846 PF12957.2 EGO57196.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) DUF445 PF04286.7 EGO57198.1 - 0.051 13.1 1.2 0.13 11.7 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) PGAP1 PF07819.8 EGO57200.1 - 8.6e-07 28.7 0.0 5.4e-05 22.8 0.0 2.2 1 1 1 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGO57200.1 - 0.00013 21.7 0.0 0.00027 20.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO57200.1 - 0.0023 17.8 0.1 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EGO57200.1 - 0.017 14.4 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2305 PF10230.4 EGO57200.1 - 0.04 13.3 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) VirionAssem_T7 PF11653.3 EGO57200.1 - 0.71 10.6 8.4 0.077 13.7 2.2 2.3 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein DUF1524 PF07510.6 EGO57201.1 - 3e-15 56.3 0.0 3.8e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 EGO57201.1 - 0.62 9.7 2.3 14 5.3 1.6 2.3 1 1 0 1 1 1 0 HNH endonuclease TFIIA PF03153.8 EGO57202.1 - 2 8.1 5.7 2.6 7.8 3.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit O-FucT PF10250.4 EGO57204.1 - 1e-14 54.4 0.0 9.7e-07 28.2 0.0 3.1 1 1 1 2 2 2 2 GDP-fucose protein O-fucosyltransferase WD40 PF00400.27 EGO57205.1 - 7.2e-25 85.9 6.8 8.9e-11 41.2 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EGO57205.1 - 1.2e-16 60.4 0.0 2.3e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EGO57205.1 - 0.0033 17.1 0.4 0.0091 15.7 0.3 1.6 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EGO57205.1 - 0.009 14.8 0.1 1.4 7.5 0.1 2.3 1 1 1 2 2 2 2 Nup133 N terminal like Apc4_WD40 PF12894.2 EGO57205.1 - 0.085 12.3 0.0 3.1 7.3 0.0 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain HATPase_c PF02518.21 EGO57206.1 - 6.6e-20 70.8 0.0 1.3e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGO57206.1 - 1e-13 51.2 0.0 2.6e-11 43.4 0.0 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EGO57206.1 - 3.8e-11 42.8 0.5 9.3e-11 41.5 0.3 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 EGO57206.1 - 7e-05 22.9 0.1 0.00022 21.3 0.1 2.0 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EGO57206.1 - 0.00083 19.4 0.1 0.0037 17.3 0.0 2.2 2 0 0 2 2 2 1 GAF domain MIase PF02426.11 EGO57206.1 - 0.15 11.8 0.0 0.87 9.4 0.0 2.3 2 0 0 2 2 2 0 Muconolactone delta-isomerase YrbL-PhoP_reg PF10707.4 EGO57206.1 - 0.25 10.6 0.0 0.57 9.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Aldo_ket_red PF00248.16 EGO57207.1 - 1e-36 126.2 0.0 1.4e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3945 PF13101.1 EGO57207.1 - 0.023 13.9 0.1 0.053 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) FAD_binding_4 PF01565.18 EGO57208.1 - 8.6e-25 86.8 3.4 8.6e-25 86.8 2.4 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EGO57208.1 - 1e-14 54.1 0.3 2.3e-14 52.9 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like SQS_PSY PF00494.14 EGO57209.1 - 1.4e-68 231.0 0.0 1.7e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase LEA_6 PF10714.4 EGO57209.1 - 0.13 12.0 0.3 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 SNF2_N PF00176.18 EGO57210.1 - 4.3e-68 229.3 0.0 6.4e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EGO57210.1 - 4.8e-27 94.0 0.0 8.6e-27 93.1 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EGO57210.1 - 1e-13 50.9 0.0 2.1e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EGO57210.1 - 6.9e-07 29.1 8.6 1.7e-06 27.9 5.8 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO57210.1 - 3.8e-05 23.2 8.7 7.5e-05 22.3 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EGO57210.1 - 0.00011 22.0 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 EGO57210.1 - 0.00092 18.8 7.6 0.002 17.7 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO57210.1 - 0.0037 17.0 8.1 0.0083 15.9 5.6 1.6 1 0 0 1 1 1 1 Ring finger domain Cut8_N PF14482.1 EGO57210.1 - 0.0037 17.2 0.6 0.016 15.1 0.4 2.1 1 0 0 1 1 1 1 Cut8 proteasome-binding domain DEAD_2 PF06733.10 EGO57210.1 - 0.015 14.7 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 zf-RING_5 PF14634.1 EGO57210.1 - 0.052 13.2 7.4 0.13 12.0 5.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain UBA_4 PF14555.1 EGO57210.1 - 0.44 10.1 0.0 0.44 10.1 0.0 2.8 4 0 0 4 4 4 0 UBA-like domain Defensin_beta PF00711.14 EGO57212.1 - 0.021 14.7 3.4 0.051 13.5 1.0 2.2 2 0 0 2 2 2 0 Beta defensin LDB19 PF13002.2 EGO57213.1 - 2.7e-35 121.6 0.2 4.5e-35 120.8 0.1 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EGO57213.1 - 4.4e-06 26.5 1.4 8.8e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Macoilin PF09726.4 EGO57213.1 - 0.45 8.7 9.0 0.73 8.0 6.3 1.2 1 0 0 1 1 1 0 Transmembrane protein Zip PF02535.17 EGO57213.1 - 0.5 9.3 13.6 0.88 8.5 9.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EGO57213.1 - 1.2 8.4 15.2 2.4 7.4 10.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Innate_immun PF12782.2 EGO57213.1 - 9.8 5.2 15.9 19 4.3 11.1 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family GTP_EFTU PF00009.22 EGO57214.1 - 1.6e-20 73.3 0.0 2.9e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGO57214.1 - 5.5e-14 52.1 0.0 1.3e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGO57214.1 - 1e-10 41.5 2.1 6.2e-10 39.0 0.7 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGO57214.1 - 0.00087 19.2 0.0 0.0023 17.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGO57214.1 - 0.0033 17.9 0.1 0.037 14.5 0.1 2.6 2 1 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 EGO57214.1 - 0.0092 15.4 0.5 0.66 9.4 0.1 3.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.1 EGO57214.1 - 0.018 14.6 0.1 0.071 12.7 0.1 2.0 1 0 0 1 1 1 0 Elongation factor Tu domain 4 DUF258 PF03193.11 EGO57214.1 - 0.033 13.3 0.1 0.12 11.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGO57214.1 - 0.057 13.2 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Dynamin family LSM PF01423.17 EGO57215.1 - 2.2e-11 43.1 0.1 3.1e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain ATP13 PF12921.2 EGO57216.1 - 8.5e-18 63.9 0.0 4.9e-17 61.4 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial ATPase expression PIG-L PF02585.12 EGO57217.1 - 7.4e-26 91.1 0.0 1.2e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Polysacc_deac_1 PF01522.16 EGO57219.1 - 4.1e-26 91.0 0.0 7e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EGO57219.1 - 0.018 14.0 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Abhydrolase_6 PF12697.2 EGO57220.1 - 7.6e-14 52.1 0.3 1.3e-13 51.3 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family MOSC_N PF03476.11 EGO57221.1 - 4.3e-10 39.3 0.0 3.3e-09 36.4 0.0 2.2 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EGO57221.1 - 2e-09 37.0 0.2 1.5e-05 24.5 0.0 2.8 2 1 0 2 2 2 2 MOSC domain DUF2077 PF09850.4 EGO57221.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) PRP38_assoc PF12871.2 EGO57224.1 - 0.0014 19.1 42.8 0.0014 19.1 29.6 5.9 2 1 3 5 5 5 2 Pre-mRNA-splicing factor 38-associated hydrophilic C-term AAA PF00004.24 EGO57225.1 - 2.2e-07 31.1 0.0 4.7e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO57225.1 - 0.00028 21.0 0.0 0.0025 17.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 EGO57225.1 - 0.0015 17.3 0.0 0.0041 15.8 0.0 1.6 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EGO57225.1 - 0.0016 19.2 0.0 0.0043 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO57225.1 - 0.0083 16.1 0.0 0.024 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EGO57225.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EGO57225.1 - 0.038 13.8 0.0 0.23 11.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain HABP4_PAI-RBP1 PF04774.10 EGO57226.1 - 3 8.3 8.1 4 7.9 0.2 3.0 3 0 0 3 3 3 0 Hyaluronan / mRNA binding family zf-MIZ PF02891.15 EGO57228.1 - 0.28 10.7 1.7 2.4 7.7 0.1 2.3 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger FA_desaturase PF00487.19 EGO57229.1 - 5.3e-21 75.2 30.8 5.3e-21 75.2 21.4 1.7 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EGO57229.1 - 2.4e-06 27.6 0.0 4.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Fungal_trans PF04082.13 EGO57230.1 - 9.4e-16 57.4 0.1 1.4e-15 56.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EGO57230.1 - 3.1e-09 36.6 12.7 0.00025 21.1 1.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO57230.1 - 1.2e-06 28.4 5.9 1.2e-06 28.4 4.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO57230.1 - 0.00094 19.3 17.4 0.057 13.7 1.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EGO57230.1 - 0.072 13.3 1.2 0.2 11.9 0.8 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGO57230.1 - 0.81 9.9 3.4 0.79 9.9 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGO57230.1 - 3.1 7.8 8.0 0.66 9.9 0.8 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger RAB3GAP2_N PF14655.1 EGO57234.1 - 0.82 8.6 3.4 1 8.2 2.3 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PAT1 PF09770.4 EGO57234.1 - 3.4 5.8 13.8 3.7 5.6 9.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.14 EGO57234.1 - 3.6 8.0 12.2 2.5 8.5 1.0 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein ATG27 PF09451.5 EGO57236.1 - 0.018 14.2 0.2 0.033 13.4 0.1 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 MAGE_N PF12440.3 EGO57236.1 - 0.39 11.0 4.3 0.86 9.9 3.0 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal MFS_1 PF07690.11 EGO57239.1 - 1.8e-30 105.8 40.1 6.1e-30 104.1 18.9 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO57239.1 - 5e-13 48.4 2.6 5e-13 48.4 1.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EGO57239.1 - 6.3e-09 34.5 2.0 6.3e-09 34.5 1.4 2.0 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Alpha_E2_glycop PF00943.14 EGO57239.1 - 0.11 11.0 0.6 0.17 10.4 0.4 1.2 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein DUF2422 PF10337.4 EGO57240.1 - 7.2e-112 374.4 3.6 7.2e-112 374.4 2.5 2.6 4 0 0 4 4 4 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EGO57240.1 - 2.8e-21 75.7 15.2 2.8e-21 75.7 10.5 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EGO57240.1 - 9.5e-06 25.3 0.1 0.0013 18.4 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2421) ALMT PF11744.3 EGO57240.1 - 0.00099 17.8 3.5 0.00099 17.8 2.5 1.8 2 0 0 2 2 2 1 Aluminium activated malate transporter AAA_12 PF13087.1 EGO57242.1 - 4.4e-28 98.0 0.0 1.1e-27 96.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGO57242.1 - 4.9e-23 81.9 0.0 1.6e-20 73.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO57242.1 - 3.6e-11 42.6 0.0 4.3e-10 39.2 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EGO57242.1 - 3.2e-07 30.1 0.0 1.6e-06 27.8 0.0 2.0 3 0 0 3 3 3 1 AAA domain ResIII PF04851.10 EGO57242.1 - 3.3e-05 23.7 0.0 7.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EGO57242.1 - 0.00013 21.3 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EGO57242.1 - 0.00076 18.5 0.0 0.25 10.2 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EGO57242.1 - 0.0014 18.8 0.0 0.0054 16.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 EGO57242.1 - 0.0024 17.5 0.0 0.014 15.0 0.0 2.2 1 1 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 EGO57242.1 - 0.031 13.7 0.0 21 4.5 0.0 4.1 4 1 0 4 4 4 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EGO57242.1 - 0.045 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain UvrD_C PF13361.1 EGO57242.1 - 0.053 12.9 0.0 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA PF00004.24 EGO57242.1 - 0.094 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EGO57242.1 - 0.098 11.8 0.0 0.71 9.0 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein DEAD PF00270.24 EGO57242.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_17 PF13207.1 EGO57242.1 - 0.16 12.7 0.0 0.45 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain HPP PF04982.8 EGO57243.1 - 5.5e-37 126.2 6.7 5.5e-37 126.2 4.7 1.5 2 0 0 2 2 2 1 HPP family RskA PF10099.4 EGO57243.1 - 0.35 10.5 4.6 0.11 12.2 0.8 1.9 2 0 0 2 2 2 0 Anti-sigma-K factor rskA eRF1_1 PF03463.10 EGO57244.1 - 4e-38 129.9 0.0 7e-38 129.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EGO57244.1 - 5.5e-23 81.7 0.0 8.3e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EGO57244.1 - 4.5e-18 65.5 0.0 9.9e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 WD40 PF00400.27 EGO57245.1 - 1.5e-27 94.3 9.5 2.2e-08 33.6 0.0 7.1 8 0 0 8 8 8 5 WD domain, G-beta repeat FAD_binding_4 PF01565.18 EGO57246.1 - 9.1e-22 77.0 1.8 9.1e-22 77.0 1.3 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EGO57246.1 - 0.0039 17.0 0.5 0.0083 16.0 0.1 1.9 2 0 0 2 2 2 1 Berberine and berberine like FAD_binding_4 PF01565.18 EGO57248.1 - 3.4e-27 94.6 0.6 5.1e-27 94.0 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGO57248.1 - 0.0019 18.0 1.1 0.0039 17.0 0.1 2.0 2 0 0 2 2 2 1 Berberine and berberine like Mqo PF06039.10 EGO57249.1 - 0.048 11.8 0.0 0.065 11.4 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) cwf21 PF08312.7 EGO57249.1 - 0.37 10.6 4.0 0.4 10.5 0.4 2.2 2 0 0 2 2 2 0 cwf21 domain M-inducer_phosp PF06617.8 EGO57249.1 - 0.38 9.7 5.2 5.3 6.0 0.5 2.2 2 0 0 2 2 2 0 M-phase inducer phosphatase Pox_I5 PF04713.7 EGO57250.1 - 0.15 11.8 1.9 0.66 9.7 1.0 2.2 1 1 1 2 2 2 0 Poxvirus protein I5 NmrA PF05368.8 EGO57252.1 - 1.9e-67 226.9 0.0 2.2e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO57252.1 - 5.2e-16 59.1 0.0 8e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGO57252.1 - 1.3e-08 33.8 0.1 1.8e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGO57252.1 - 0.00074 19.0 0.1 0.0022 17.4 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EGO57252.1 - 0.0018 18.2 0.2 0.0026 17.7 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EGO57252.1 - 0.04 12.8 0.1 0.065 12.1 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EGO57252.1 - 0.51 10.6 2.7 4.7 7.5 0.0 2.8 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_43 PF04616.9 EGO57253.1 - 2.6e-61 207.2 2.7 3.2e-61 206.9 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 AbfB PF05270.8 EGO57253.1 - 2.7e-14 53.0 0.0 4.9e-10 39.2 0.0 2.4 1 1 1 2 2 2 2 Alpha-L-arabinofuranosidase B (ABFB) Kelch_5 PF13854.1 EGO57254.1 - 2.3e-13 49.7 15.8 7.5e-10 38.5 0.5 5.9 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.1 EGO57254.1 - 1.7e-08 34.0 8.8 0.024 14.4 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EGO57254.1 - 0.00056 19.9 15.7 1.2 9.4 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EGO57254.1 - 0.00075 19.1 8.9 0.096 12.4 0.0 5.6 5 0 0 5 5 5 1 Kelch motif SKG6 PF08693.5 EGO57254.1 - 0.017 14.4 0.3 0.035 13.4 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.8 EGO57254.1 - 0.018 13.7 0.3 0.026 13.1 0.2 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Kelch_1 PF01344.20 EGO57254.1 - 0.025 14.0 12.5 0.4 10.2 0.0 5.3 6 0 0 6 6 6 0 Kelch motif MFS_1 PF07690.11 EGO57255.1 - 9.9e-35 119.8 48.1 4e-34 117.8 33.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3445 PF11927.3 EGO57256.1 - 1.3e-70 237.6 0.2 1.7e-70 237.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) SRPRB PF09439.5 EGO57257.1 - 0.17 11.1 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Glyco_hydro_17 PF00332.13 EGO57258.1 - 6.7e-06 25.3 1.1 1.5e-05 24.2 0.7 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Macoilin PF09726.4 EGO57258.1 - 5.8 5.0 5.9 7.4 4.7 4.1 1.1 1 0 0 1 1 1 0 Transmembrane protein CHORD PF04968.7 EGO57261.1 - 0.017 15.3 1.9 0.017 15.3 1.3 2.1 2 0 0 2 2 2 0 CHORD Oxidored-like PF09791.4 EGO57262.1 - 0.15 11.5 2.2 0.42 10.1 1.5 1.8 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal CHORD PF04968.7 EGO57262.1 - 5.8 7.2 5.6 0.75 10.0 0.1 2.2 3 0 0 3 3 3 0 CHORD TFIIA PF03153.8 EGO57263.1 - 0.031 14.2 2.8 0.034 14.0 1.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAF1A PF12253.3 EGO57263.1 - 9.4 6.4 16.2 0.52 10.4 7.4 1.8 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A Aminotran_5 PF00266.14 EGO57264.1 - 5.5e-10 38.5 0.0 1.4e-09 37.1 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGO57264.1 - 0.0022 16.3 0.0 0.0032 15.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGO57264.1 - 0.14 11.1 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IDO PF01231.13 EGO57265.1 - 8.2e-29 100.2 0.0 1.1e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase IDO PF01231.13 EGO57266.1 - 2.3e-66 224.0 0.0 2.6e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase AAA PF00004.24 EGO57267.1 - 9.4e-10 38.7 4.1 2.4e-07 31.0 2.8 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EGO57267.1 - 0.22 10.6 2.3 5.8 5.9 0.4 2.4 1 1 1 2 2 2 0 KaiC Tri3 PF07428.6 EGO57269.1 - 0.00027 19.7 0.0 0.00077 18.2 0.0 1.6 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 SSFA2_C PF14723.1 EGO57269.1 - 0.098 12.3 0.7 0.23 11.1 0.5 1.6 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus p450 PF00067.17 EGO57270.1 - 3e-44 151.3 0.0 4.2e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EGO57271.1 - 9.1e-20 70.8 0.0 9.7e-19 67.5 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57271.1 - 1.2e-06 27.8 0.0 0.045 12.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGO57271.1 - 3.5e-05 22.8 0.0 0.13 11.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EGO57271.1 - 0.013 15.2 0.2 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 EGO57273.1 - 3.1e-05 23.2 0.0 4.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Peptidase_C14 PF00656.17 EGO57274.1 - 4.3e-06 26.5 0.0 4.2e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 Caspase domain HET PF06985.6 EGO57276.1 - 3e-22 79.2 1.8 2e-21 76.5 1.2 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DDDD PF10161.4 EGO57276.1 - 0.17 11.5 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative mitochondrial precursor protein Pkinase PF00069.20 EGO57277.1 - 2.8e-17 62.7 0.1 2.2e-15 56.5 0.1 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57277.1 - 0.0011 18.0 0.0 0.56 9.2 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 EGO57277.1 - 0.0077 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO57277.1 - 0.18 11.5 0.1 0.18 11.5 0.1 2.1 2 2 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 EGO57280.1 - 0.092 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 EGO57282.1 - 0.00011 21.4 0.1 0.03 13.4 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain GPI-anchored PF10342.4 EGO57288.1 - 3.8e-14 52.9 0.5 3.8e-14 52.9 0.3 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Med3 PF11593.3 EGO57288.1 - 2 7.5 18.1 2.9 7.0 12.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Macoilin PF09726.4 EGO57288.1 - 8.4 4.5 8.1 8.3 4.5 5.6 1.0 1 0 0 1 1 1 0 Transmembrane protein HATPase_c_2 PF13581.1 EGO57290.1 - 0.00063 19.5 0.0 0.00084 19.1 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF1455 PF07306.6 EGO57290.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) Ank_2 PF12796.2 EGO57292.1 - 2.9e-14 53.1 0.2 2.3e-07 31.0 0.0 4.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO57292.1 - 7.1e-13 48.6 0.2 7.9e-06 26.2 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO57292.1 - 6.5e-09 35.7 0.5 0.0053 16.9 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EGO57292.1 - 1.2e-08 34.2 2.2 0.00095 18.8 0.0 4.7 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EGO57292.1 - 4.7e-07 29.4 0.9 0.011 15.8 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Cnd1 PF12717.2 EGO57293.1 - 0.077 12.8 0.1 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Rubella_Capsid PF05750.6 EGO57294.1 - 0.14 11.5 7.1 0.15 11.4 4.4 1.5 1 1 0 1 1 1 0 Rubella capsid protein Ycf1 PF05758.7 EGO57295.1 - 0.0097 13.6 16.9 0.012 13.4 11.7 1.1 1 0 0 1 1 1 1 Ycf1 Daxx PF03344.10 EGO57295.1 - 0.0098 14.4 30.4 0.012 14.1 21.1 1.1 1 0 0 1 1 1 1 Daxx Family BUD22 PF09073.5 EGO57295.1 - 0.41 9.6 29.4 0.6 9.1 20.4 1.3 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.7 EGO57295.1 - 0.51 8.6 36.3 0.65 8.2 25.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Spore_coat_CotO PF14153.1 EGO57295.1 - 0.75 9.2 26.9 1.3 8.4 18.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Nop14 PF04147.7 EGO57295.1 - 3.1 5.5 38.3 4.5 5.0 26.6 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 EGO57295.1 - 3.3 6.6 34.8 4.7 6.0 24.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.9 EGO57295.1 - 4.3 5.2 29.9 6.8 4.5 20.8 1.2 1 0 0 1 1 1 0 CDC45-like protein MIP-T3 PF10243.4 EGO57295.1 - 5.9 5.2 32.1 7.6 4.8 22.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CT47 PF15623.1 EGO57295.1 - 7.7 6.1 36.0 13 5.4 24.9 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 TFIIA PF03153.8 EGO57300.1 - 0.021 14.7 15.8 0.029 14.2 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.5 EGO57300.1 - 0.12 11.4 18.5 0.14 11.1 12.9 1.1 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 EGO57300.1 - 0.23 9.9 16.3 0.26 9.7 11.3 1.2 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 EGO57300.1 - 0.26 9.9 19.7 0.35 9.5 13.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 EGO57300.1 - 1.2 8.3 18.9 1.9 7.7 13.1 1.3 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.6 EGO57300.1 - 1.6 6.4 10.1 1.9 6.2 7.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 EGO57300.1 - 2.1 6.1 20.8 2.4 5.9 14.4 1.1 1 0 0 1 1 1 0 Nop14-like family Dicty_REP PF05086.7 EGO57300.1 - 2.3 5.8 6.5 3.2 5.3 4.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NOA36 PF06524.7 EGO57300.1 - 3.4 6.8 14.9 4.8 6.3 10.3 1.3 1 0 0 1 1 1 0 NOA36 protein CDC27 PF09507.5 EGO57301.1 - 0.025 13.8 1.9 0.03 13.5 1.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TAP42 PF04177.7 EGO57301.1 - 0.17 10.8 5.0 0.23 10.3 3.4 1.2 1 0 0 1 1 1 0 TAP42-like family zf-CCHC_6 PF15288.1 EGO57301.1 - 3.3 7.4 8.0 0.34 10.5 0.2 2.5 2 0 0 2 2 2 0 Zinc knuckle Neisseria_TspB PF05616.8 EGO57301.1 - 8.5 4.6 12.2 10 4.3 8.5 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Glyco_transf_15 PF01793.11 EGO57303.1 - 5.6e-131 436.3 0.1 7.1e-131 436.0 0.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Myb_DNA-bind_6 PF13921.1 EGO57304.1 - 6.3e-05 23.0 0.2 0.0002 21.3 0.2 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGO57304.1 - 0.0092 16.0 0.2 0.045 13.8 0.3 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain ILVD_EDD PF00920.16 EGO57305.1 - 2.3e-192 640.0 1.2 2.8e-192 639.8 0.9 1.0 1 0 0 1 1 1 1 Dehydratase family Myb_DNA-binding PF00249.26 EGO57308.1 - 3.2e-12 46.3 1.8 1e-06 28.6 0.6 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGO57308.1 - 5.8e-11 42.3 0.4 5.9e-06 26.2 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Glyco_hydro_16 PF00722.16 EGO57310.1 - 2e-44 151.0 5.0 3.4e-44 150.3 3.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Clr5 PF14420.1 EGO57311.1 - 5.6e-18 64.5 1.1 1e-17 63.7 0.8 1.5 1 0 0 1 1 1 1 Clr5 domain DUF4604 PF15377.1 EGO57312.1 - 2.2e-16 60.4 22.6 9.8e-15 55.1 15.6 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) Nop14 PF04147.7 EGO57312.1 - 6.8 4.4 20.7 8.6 4.1 14.4 1.0 1 0 0 1 1 1 0 Nop14-like family COX5B PF01215.14 EGO57313.1 - 1.2e-38 131.8 0.0 1.5e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 EGO57313.1 - 0.032 13.7 0.5 5.2 6.6 0.2 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger NUT_C PF12882.2 EGO57314.1 - 0.14 11.7 0.2 0.25 10.9 0.1 1.5 2 0 0 2 2 2 0 NUT protein C terminal OHCU_decarbox PF09349.5 EGO57317.1 - 2.7e-45 154.4 0.0 3.3e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase Dynamin_N PF00350.18 EGO57318.1 - 2.2e-33 115.4 0.1 2.2e-33 115.4 0.1 2.6 3 0 0 3 3 3 1 Dynamin family Dynamin_M PF01031.15 EGO57318.1 - 6.6e-18 64.5 0.1 2.5e-17 62.5 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region GED PF02212.13 EGO57318.1 - 0.00013 21.7 2.6 0.00034 20.4 0.1 2.9 2 1 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGO57318.1 - 0.0057 16.5 0.5 0.051 13.5 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO57318.1 - 0.0094 15.2 0.1 1 8.6 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EGO57318.1 - 0.049 14.1 0.0 0.16 12.4 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein DUF2235 PF09994.4 EGO57319.1 - 8.2e-78 261.5 0.0 1.1e-77 261.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) AAA_33 PF13671.1 EGO57320.1 - 0.91 9.3 7.6 0.12 12.2 1.1 2.5 2 0 0 2 2 2 0 AAA domain PhzC-PhzF PF02567.11 EGO57321.1 - 1.1e-38 133.0 0.8 6.4e-38 130.5 0.6 2.0 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Prp19 PF08606.6 EGO57322.1 - 6.8e-31 105.8 2.0 1.4e-30 104.8 1.4 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EGO57322.1 - 4.9e-14 51.5 0.1 0.0018 18.1 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 EGO57322.1 - 2.9e-06 27.1 0.1 0.0047 16.6 0.0 3.5 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EGO57322.1 - 6.9e-05 21.8 0.0 0.063 12.0 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region zf-Nse PF11789.3 EGO57322.1 - 0.00097 18.6 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Cytochrom_D1 PF02239.11 EGO57322.1 - 0.0025 16.1 0.0 0.0077 14.5 0.0 1.8 2 0 0 2 2 2 1 Cytochrome D1 heme domain Fim-adh_lectin PF09222.5 EGO57322.1 - 0.022 14.0 0.3 0.037 13.3 0.2 1.3 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain Hemerythrin PF01814.18 EGO57322.1 - 0.072 13.2 0.6 0.16 12.1 0.3 1.5 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF3312 PF11768.3 EGO57322.1 - 0.075 11.2 0.0 0.11 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) zf-RING_5 PF14634.1 EGO57323.1 - 0.0076 15.9 5.5 0.023 14.4 3.9 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGO57323.1 - 0.14 11.8 5.3 0.38 10.4 3.7 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGO57323.1 - 0.18 11.5 1.1 0.39 10.4 0.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EGO57323.1 - 1 9.4 8.0 0.097 12.7 2.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGO57323.1 - 1.6 8.6 5.1 1.4 8.8 1.7 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING POX PF07526.6 EGO57323.1 - 9 6.5 6.8 1.6 8.9 0.2 2.8 3 0 0 3 3 3 0 Associated with HOX Osmo_MPGsynth PF09488.5 EGO57328.1 - 1.3e-145 484.9 0.0 1.6e-145 484.6 0.0 1.0 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) GST_N PF02798.15 EGO57333.1 - 9e-10 38.6 0.0 2.1e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGO57333.1 - 3.6e-08 33.4 0.0 7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO57333.1 - 8.4e-08 32.1 0.0 2.9e-07 30.3 0.0 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO57333.1 - 1.2e-06 28.4 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO57333.1 - 1.2e-05 25.6 0.0 1.9e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO57333.1 - 0.00025 20.8 0.0 0.00052 19.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAD_binding_3 PF01494.14 EGO57335.1 - 5e-74 249.4 0.0 6.6e-74 249.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGO57335.1 - 2.7e-45 153.9 0.0 4.5e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EGO57335.1 - 5.1e-05 22.3 0.3 0.0061 15.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO57335.1 - 0.0014 17.6 0.0 0.0077 15.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EGO57335.1 - 0.0014 17.7 0.0 0.0028 16.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EGO57335.1 - 0.0031 16.6 0.1 0.005 15.9 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO57335.1 - 0.0066 16.4 0.1 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGO57335.1 - 0.012 14.6 0.3 0.14 11.2 0.0 2.7 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EGO57335.1 - 0.013 15.5 0.0 0.072 13.1 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO57335.1 - 0.024 15.0 0.0 0.25 11.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EGO57335.1 - 0.033 13.0 0.0 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase AlaDh_PNT_C PF01262.16 EGO57335.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Abhydrolase_5 PF12695.2 EGO57336.1 - 1.5e-17 63.6 0.0 1.9e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO57336.1 - 1.5e-10 41.4 1.7 1.4e-06 28.4 1.2 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO57336.1 - 1.5e-07 30.8 0.1 0.0022 17.2 0.2 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EGO57336.1 - 5.5e-06 26.1 0.1 3.2e-05 23.5 0.1 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 EGO57336.1 - 4.6e-05 22.7 0.0 6.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EGO57336.1 - 0.00034 20.1 0.0 0.00049 19.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase PhoPQ_related PF10142.4 EGO57336.1 - 0.0014 17.1 0.0 0.019 13.4 0.0 2.0 1 1 1 2 2 2 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_4 PF08386.5 EGO57336.1 - 0.031 14.1 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF915 PF06028.6 EGO57336.1 - 0.047 12.7 0.0 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) VirJ PF06057.6 EGO57336.1 - 0.049 13.4 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) FMO-like PF00743.14 EGO57337.1 - 2.2e-28 98.7 0.2 2.4e-21 75.5 0.1 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGO57337.1 - 3.8e-14 53.2 0.0 1.1e-13 51.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO57337.1 - 1.7e-09 37.0 0.0 2.3e-07 30.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGO57337.1 - 2.8e-07 30.4 0.0 1.5e-06 28.0 0.0 2.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGO57337.1 - 0.00014 21.7 0.0 0.0003 20.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO57337.1 - 0.00015 21.7 0.0 0.00056 19.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DnaJ PF00226.26 EGO57338.1 - 1.8e-21 75.6 0.8 1.8e-21 75.6 0.6 1.9 2 0 0 2 2 2 1 DnaJ domain Fib_alpha PF08702.5 EGO57338.1 - 0.036 14.1 0.5 0.036 14.1 0.4 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1912 PF08930.5 EGO57338.1 - 0.083 12.9 1.5 0.77 9.8 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1912) ArdA PF07275.6 EGO57338.1 - 1.7 8.9 6.9 0.67 10.1 0.6 2.3 1 1 1 2 2 2 0 Antirestriction protein (ArdA) ATG16 PF08614.6 EGO57338.1 - 3.8 7.2 14.8 24 4.6 9.3 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FUSC PF04632.7 EGO57338.1 - 5 5.4 7.9 3.1 6.1 4.1 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family CCDC92 PF14916.1 EGO57339.1 - 0.13 11.8 5.8 14 5.3 0.0 3.0 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Ribosomal_L18e PF00828.14 EGO57342.1 - 4.9e-19 68.9 0.2 9.6e-19 68.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 POM121 PF15229.1 EGO57342.1 - 0.12 11.8 1.7 0.24 10.8 1.2 1.4 1 0 0 1 1 1 0 POM121 family PX PF00787.19 EGO57343.1 - 8.4e-18 64.2 0.1 1.8e-17 63.1 0.1 1.5 1 0 0 1 1 1 1 PX domain NBP1 PF08537.5 EGO57343.1 - 5.6 6.0 12.2 0.11 11.6 0.2 2.3 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 Cullin_binding PF03556.10 EGO57344.1 - 4.5e-31 107.4 1.3 6.3e-31 106.9 0.9 1.2 1 0 0 1 1 1 1 Cullin binding Ribosomal_S6 PF01250.12 EGO57345.1 - 5.8e-13 48.4 0.0 6.8e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 DUF3716 PF12511.3 EGO57346.1 - 2.3e-10 39.9 8.7 4.4e-10 39.0 6.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) zf-C4H2 PF10146.4 EGO57346.1 - 0.096 12.6 9.6 0.028 14.4 3.8 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein Chs3p PF12271.3 EGO57347.1 - 2.7e-141 469.7 14.2 3.1e-141 469.5 9.8 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 EGO57347.1 - 0.73 9.7 9.2 0.22 11.4 2.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) MpPF26 PF07666.6 EGO57347.1 - 0.8 9.5 9.5 1.5 8.6 0.4 2.6 2 0 0 2 2 2 0 M penetrans paralogue family 26 Arrestin_C PF02752.17 EGO57348.1 - 2.7e-17 63.1 0.0 1.5e-16 60.7 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EGO57348.1 - 3.6e-07 30.1 6.5 0.00045 20.0 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Dak1_2 PF13684.1 EGO57348.1 - 0.34 9.8 0.0 0.58 9.0 0.0 1.3 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Pkinase PF00069.20 EGO57350.1 - 2.9e-10 39.7 0.0 4.3e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57350.1 - 0.0029 16.7 0.0 0.08 11.9 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase NPV_P10 PF05531.7 EGO57351.1 - 0.00054 20.1 13.1 0.0016 18.6 0.9 7.4 3 2 6 9 9 9 2 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EGO57351.1 - 0.00068 19.2 85.4 0.016 14.8 7.8 6.4 2 2 4 6 6 6 4 IncA protein TMF_DNA_bd PF12329.3 EGO57351.1 - 0.013 15.3 93.2 0.13 12.0 0.6 9.9 6 3 4 10 10 10 0 TATA element modulatory factor 1 DNA binding HOOK PF05622.7 EGO57351.1 - 0.052 11.3 84.5 0.022 12.5 16.7 4.1 1 1 3 4 4 4 0 HOOK protein GAS PF13851.1 EGO57351.1 - 0.08 12.1 81.6 0.11 11.6 3.5 6.7 3 2 4 7 7 7 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EGO57351.1 - 0.33 10.0 52.6 0.076 12.1 3.1 5.8 3 1 4 7 7 7 0 Reovirus sigma C capsid protein DUF869 PF05911.6 EGO57351.1 - 0.49 8.5 75.3 0.077 11.2 5.5 4.3 1 1 3 4 4 4 0 Plant protein of unknown function (DUF869) AAA_13 PF13166.1 EGO57351.1 - 0.76 8.1 55.9 0.2 10.0 9.0 3.8 1 1 2 3 3 3 0 AAA domain AAA_27 PF13514.1 EGO57351.1 - 2.9 5.4 84.0 0.7 7.5 14.1 2.1 1 1 1 2 2 2 0 AAA domain Filament PF00038.16 EGO57351.1 - 4.5 6.6 84.0 1.6 8.0 9.2 6.1 1 1 4 5 5 5 0 Intermediate filament protein CENP-F_leu_zip PF10473.4 EGO57351.1 - 6.7 6.5 94.1 0.98 9.2 10.6 6.6 1 1 4 6 6 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.6 EGO57351.1 - 7.9 4.6 77.2 0.24 9.6 18.9 3.9 1 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Cyclin PF08613.6 EGO57354.1 - 2.8e-15 57.0 0.0 5.2e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EGO57354.1 - 7.2e-05 22.3 0.2 7.2e-05 22.3 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF3815 PF12821.2 EGO57354.1 - 0.055 13.3 1.2 0.1 12.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3815) Spc7_N PF15402.1 EGO57354.1 - 6.2 4.7 16.9 10 3.9 11.7 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF4175 PF13779.1 EGO57354.1 - 8.3 3.9 15.8 12 3.4 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PrmA PF06325.8 EGO57359.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SnoaL_4 PF13577.1 EGO57360.1 - 1.7e-06 27.9 0.2 2.5e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain Thioredoxin PF00085.15 EGO57361.1 - 2e-25 88.4 0.2 2.8e-25 87.9 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGO57361.1 - 6.7e-07 29.3 0.1 6.3e-06 26.2 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EGO57361.1 - 1.1e-05 25.5 0.2 0.00015 21.9 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EGO57361.1 - 0.00034 20.3 0.0 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EGO57361.1 - 0.0043 16.6 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.11 EGO57361.1 - 0.014 14.8 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_7 PF13899.1 EGO57361.1 - 0.018 15.0 0.3 0.041 13.9 0.2 1.6 1 1 0 1 1 1 0 Thioredoxin-like HyaE PF07449.6 EGO57361.1 - 0.041 13.7 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Baculo_PEP_C PF04513.7 EGO57364.1 - 0.14 11.9 0.2 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sas10_Utp3 PF04000.10 EGO57364.1 - 1.6 8.9 4.2 0.52 10.5 0.2 2.2 2 1 1 3 3 3 0 Sas10/Utp3/C1D family Fungal_trans_2 PF11951.3 EGO57365.1 - 2.5e-30 105.3 0.7 5.6e-30 104.2 0.5 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO57365.1 - 5.7e-08 32.5 5.0 9.8e-08 31.7 3.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EGO57366.1 - 1e-40 139.5 55.1 2.9e-40 138.0 37.8 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily COX2_TM PF02790.10 EGO57366.1 - 0.025 14.5 0.9 0.1 12.5 0.6 2.1 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain DUF805 PF05656.9 EGO57366.1 - 5.5 6.8 0.0 4 7.2 1.6 5.3 5 2 1 6 6 6 0 Protein of unknown function (DUF805) SAS4 PF15460.1 EGO57367.1 - 0.076 12.8 3.0 0.14 12.0 2.1 1.4 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 DUF2001 PF09393.5 EGO57371.1 - 0.039 13.6 0.0 0.044 13.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2001) UCR_UQCRX_QCR9 PF05365.7 EGO57372.1 - 0.023 14.3 1.4 0.023 14.3 1.0 1.6 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like RVT_1 PF00078.22 EGO57377.1 - 3.6e-06 26.4 0.7 3.8e-06 26.4 0.5 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF226 PF02890.9 EGO57377.1 - 0.0029 17.3 4.1 0.0038 17.0 2.8 1.1 1 0 0 1 1 1 1 Borrelia family of unknown function DUF226 Gin PF10764.4 EGO57377.1 - 0.021 14.5 2.2 0.068 12.9 0.4 2.1 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin CorA PF01544.13 EGO57381.1 - 2.2e-28 99.1 2.6 6.7e-25 87.7 1.2 2.4 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein Carb_bind PF10645.4 EGO57382.1 - 1.1e-28 98.8 7.4 2.1e-28 97.8 5.1 1.5 1 0 0 1 1 1 1 Carbohydrate binding Methyltransf_2 PF00891.13 EGO57383.1 - 2.6e-37 128.3 0.0 3.5e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGO57383.1 - 0.00013 22.4 0.0 0.00035 21.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO57383.1 - 0.00084 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EGO57383.1 - 0.0035 17.0 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO57383.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EGO57383.1 - 0.062 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGO57383.1 - 0.17 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TauD PF02668.11 EGO57384.1 - 1.2e-50 172.6 0.0 1.5e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 EGO57385.1 - 4.2e-31 107.9 15.4 4.2e-31 107.9 10.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FMO-like PF00743.14 EGO57386.1 - 2.1e-42 145.0 0.0 3.4e-19 68.4 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGO57386.1 - 2.5e-20 73.4 0.0 3.3e-19 69.7 0.0 2.8 4 1 0 4 4 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO57386.1 - 7.8e-10 38.1 0.3 6e-06 25.3 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGO57386.1 - 9.3e-10 38.7 0.0 0.0027 17.5 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO57386.1 - 1.8e-09 37.4 0.3 8.9e-09 35.2 0.0 2.3 2 1 1 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO57386.1 - 5.1e-09 35.5 5.4 1.1e-06 27.8 1.5 3.8 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EGO57386.1 - 2.2e-07 30.7 0.9 0.00044 20.0 0.0 4.3 4 1 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EGO57386.1 - 2.6e-06 27.7 0.5 0.00079 19.7 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EGO57386.1 - 3.1e-05 23.2 0.0 0.0027 16.8 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Shikimate_DH PF01488.15 EGO57386.1 - 0.00013 22.0 0.0 0.41 10.7 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EGO57386.1 - 0.00047 19.3 0.3 0.0068 15.5 0.2 2.1 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EGO57386.1 - 0.0011 18.1 0.0 0.0024 17.0 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO57386.1 - 0.0024 16.7 0.9 0.0063 15.4 0.6 1.7 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGO57386.1 - 0.0027 16.2 0.4 0.0074 14.7 0.5 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EGO57386.1 - 0.0038 16.3 0.4 0.0077 15.3 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 EGO57386.1 - 0.039 13.5 0.1 1.7 8.2 0.1 2.8 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EGO57386.1 - 0.05 13.8 0.0 5 7.4 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EGO57386.1 - 0.054 13.1 0.6 0.13 11.9 0.4 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EGO57386.1 - 0.076 12.8 0.1 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Trp_halogenase PF04820.9 EGO57386.1 - 0.095 11.3 0.4 3.4 6.1 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 EGO57386.1 - 0.17 10.6 2.2 0.25 10.1 0.8 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF2293 PF10056.4 EGO57387.1 - 5.7e-32 109.5 1.0 5.7e-32 109.5 0.7 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) Peptidase_S46 PF10459.4 EGO57387.1 - 6.1 5.1 12.9 2 6.7 6.4 1.7 1 1 1 2 2 2 0 Peptidase S46 Scytalone_dh PF02982.9 EGO57388.1 - 9.8e-84 278.7 0.3 1.1e-83 278.5 0.2 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EGO57388.1 - 6.4e-05 22.8 0.0 9.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF3722 PF12519.3 EGO57389.1 - 4.4e-85 285.0 0.0 5.8e-85 284.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Ank_2 PF12796.2 EGO57390.1 - 1.9e-08 34.5 0.0 3.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGO57390.1 - 5.8e-08 32.1 0.1 2.9e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EGO57390.1 - 8.3e-08 32.5 0.0 3.3e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO57390.1 - 1.8e-05 24.8 0.0 3.5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO57390.1 - 0.0065 16.6 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat DUF1843 PF08898.5 EGO57390.1 - 0.0065 16.4 0.3 0.083 12.9 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF1843) Ribosomal_S19e PF01090.14 EGO57391.1 - 1.4e-58 196.3 0.2 1.5e-58 196.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ricin_B_lectin PF00652.17 EGO57392.1 - 1.9e-16 60.2 0.9 3.2e-09 36.8 0.1 3.7 3 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain Fe-S_biosyn PF01521.15 EGO57393.1 - 5.3e-07 29.5 0.0 0.00048 20.0 0.0 2.2 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ribosomal_L30_N PF08079.7 EGO57394.1 - 3.4e-25 87.8 17.5 6e-25 87.0 12.1 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EGO57394.1 - 1.2e-19 69.6 2.6 1.3e-19 69.5 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_S11 PF00411.14 EGO57395.1 - 1.1e-40 138.2 0.4 1.3e-40 137.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 EGO57395.1 - 0.049 12.5 0.0 0.061 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) eIF-3c_N PF05470.7 EGO57396.1 - 1e-170 568.7 25.9 1e-170 568.7 17.9 3.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EGO57396.1 - 2.4e-14 53.5 0.0 1e-13 51.5 0.0 2.2 1 0 0 1 1 1 1 PCI domain DUF357 PF04010.8 EGO57396.1 - 0.016 14.8 0.2 0.053 13.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF357) TFIIF_alpha PF05793.7 EGO57396.1 - 0.11 10.8 32.9 0.18 10.1 22.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mem_trans PF03547.13 EGO57396.1 - 0.2 9.9 1.0 0.26 9.5 0.7 1.4 1 0 0 1 1 1 0 Membrane transport protein Daxx PF03344.10 EGO57396.1 - 1.4 7.3 30.6 2.1 6.7 21.2 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EGO57396.1 - 3.3 5.6 24.2 5.8 4.8 16.8 1.4 1 0 0 1 1 1 0 CDC45-like protein PROCN PF08083.6 EGO57397.1 - 1e-220 732.3 8.5 1.7e-220 731.6 5.9 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EGO57397.1 - 1e-125 417.6 1.7 1.7e-125 416.9 1.2 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EGO57397.1 - 2.1e-94 313.2 2.0 3.6e-94 312.4 0.7 2.0 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EGO57397.1 - 3.4e-76 254.0 4.6 3.5e-76 254.0 1.4 2.3 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EGO57397.1 - 3.9e-67 224.0 0.1 9.3e-67 222.8 0.1 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EGO57397.1 - 6e-44 147.8 0.1 1.6e-43 146.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EGO57397.1 - 1.8e-43 147.2 2.3 2e-43 147.0 0.0 2.3 3 0 0 3 3 3 1 PROCT (NUC072) domain DUF3753 PF12575.3 EGO57397.1 - 0.097 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Myb_DNA-bind_6 PF13921.1 EGO57398.1 - 3.2e-15 55.9 0.1 8.8e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGO57398.1 - 1.3e-12 47.5 0.2 6.1e-05 22.9 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4085 PF13315.1 EGO57398.1 - 0.047 13.0 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) HTH_AsnC-type PF13404.1 EGO57398.1 - 0.13 11.8 0.0 0.85 9.2 0.0 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain ApbA_C PF08546.6 EGO57399.1 - 9.9e-36 122.4 0.0 1.6e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EGO57399.1 - 2.8e-26 91.7 0.0 5e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Exonuc_V_gamma PF04257.9 EGO57399.1 - 0.013 13.4 0.0 0.02 12.9 0.0 1.2 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit SNF2_N PF00176.18 EGO57400.1 - 9.1e-58 195.4 0.1 1.2e-50 171.9 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO57400.1 - 5.6e-16 58.1 0.0 1.3e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGO57400.1 - 2.4e-05 23.2 0.0 5.1e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EGO57401.1 - 5.9e-46 156.0 0.0 1.4e-44 151.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO57401.1 - 1.4e-28 98.5 0.0 2.8e-28 97.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO57401.1 - 0.00015 21.6 0.0 0.00057 19.7 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EGO57401.1 - 0.00096 17.6 0.0 0.064 11.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) DUF2443 PF10398.4 EGO57401.1 - 0.013 15.2 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Helicase_C_2 PF13307.1 EGO57401.1 - 0.032 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain Glyoxalase_3 PF13468.1 EGO57401.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase-like domain HET PF06985.6 EGO57402.1 - 7.2e-25 87.7 0.0 1.7e-24 86.5 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) hSH3 PF14603.1 EGO57403.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Helically-extended SH3 domain Mpv17_PMP22 PF04117.7 EGO57404.1 - 4.7e-12 45.3 5.2 1.1e-10 40.9 2.9 2.2 2 0 0 2 2 2 2 Mpv17 / PMP22 family DER1 PF04511.10 EGO57404.1 - 0.023 14.2 1.2 0.036 13.5 0.9 1.3 1 0 0 1 1 1 0 Der1-like family EAP30 PF04157.11 EGO57405.1 - 9.6e-66 221.1 0.0 1.1e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family AAR2 PF05282.6 EGO57406.1 - 2.4e-50 171.4 0.0 3.2e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein DUF4604 PF15377.1 EGO57406.1 - 0.41 10.8 4.3 0.51 10.5 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) NBP1 PF08537.5 EGO57408.1 - 0.064 12.4 0.9 0.094 11.9 0.7 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 APC_CDC26 PF10471.4 EGO57408.1 - 1.4 9.7 8.8 0.069 13.8 1.8 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Phos_pyr_kin PF08543.7 EGO57409.1 - 1.6e-79 266.5 2.7 5.4e-79 264.8 1.9 1.8 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EGO57409.1 - 2.5e-49 167.9 0.3 3.7e-49 167.3 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EGO57409.1 - 7.3e-08 31.8 0.2 1.3e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF2288 PF10052.4 EGO57409.1 - 0.021 14.5 0.1 0.59 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2288) TPR_11 PF13414.1 EGO57410.1 - 2.1e-20 72.1 9.6 1.4e-11 43.8 0.1 3.1 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EGO57410.1 - 5.3e-16 57.4 7.8 1.4e-08 33.9 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGO57410.1 - 1.7e-13 49.3 8.3 2.1e-06 27.1 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGO57410.1 - 2e-13 50.0 1.3 1e-07 31.8 0.1 2.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGO57410.1 - 1.2e-11 43.4 2.0 3.8e-05 23.1 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGO57410.1 - 4.1e-09 36.3 1.7 0.034 14.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGO57410.1 - 3.6e-08 32.5 0.9 1.5e-06 27.5 0.0 3.1 2 1 1 3 3 2 1 Tetratricopeptide repeat PB1 PF00564.19 EGO57410.1 - 7e-08 32.0 0.1 1.5e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_17 PF13431.1 EGO57410.1 - 3.7e-07 29.8 0.2 0.0046 17.0 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO57410.1 - 3.2e-05 24.4 1.1 0.00069 20.2 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGO57410.1 - 0.00034 21.0 1.4 0.0083 16.6 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGO57410.1 - 0.00042 20.1 5.3 0.21 11.4 0.1 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_4 PF07721.9 EGO57410.1 - 0.032 14.6 1.0 5.9 7.6 0.0 3.4 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGO57410.1 - 0.037 14.3 1.0 0.29 11.4 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGO57410.1 - 0.04 13.8 0.4 1.3 9.0 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 EGO57410.1 - 0.057 13.3 0.0 0.36 10.7 0.0 2.4 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 EGO57410.1 - 0.058 13.5 3.2 0.07 13.2 0.3 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.4 EGO57410.1 - 0.067 11.7 0.7 0.12 10.8 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) Apc5 PF12862.2 EGO57410.1 - 0.1 12.4 0.3 0.33 10.8 0.1 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 HMA PF00403.21 EGO57411.1 - 1.1e-12 47.8 0.0 2.7e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 EGO57411.1 - 8.9e-10 38.8 0.0 1.4e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF4301 PF14134.1 EGO57411.1 - 0.18 10.2 0.0 0.25 9.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) Ribosomal_L13 PF00572.13 EGO57412.1 - 8.1e-38 129.3 0.0 1.1e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.13 EGO57413.1 - 7.2e-85 282.0 2.1 1.8e-46 157.6 0.4 2.0 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.1 EGO57414.1 - 1.6e-136 454.7 0.5 1.4e-134 448.3 0.1 2.4 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EGO57414.1 - 1.1e-90 302.5 0.0 1.8e-89 298.6 0.0 2.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EGO57414.1 - 3.5e-43 146.2 0.1 1.3e-41 141.1 0.0 2.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EGO57414.1 - 1.4e-26 92.2 0.9 1.7e-25 88.7 0.1 3.1 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EGO57414.1 - 1.8e-14 53.1 5.3 5e-14 51.7 3.7 1.8 1 0 0 1 1 1 1 Hr1 repeat HEAT_EZ PF13513.1 EGO57414.1 - 0.085 13.3 3.2 22 5.7 0.0 4.7 5 0 0 5 5 5 0 HEAT-like repeat NdhL PF10716.4 EGO57415.1 - 0.23 11.2 5.6 0.42 10.4 1.8 2.4 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit HSBP1 PF06825.7 EGO57416.1 - 6.9e-06 25.5 0.4 0.00012 21.5 0.0 2.6 2 0 0 2 2 2 1 Heat shock factor binding protein 1 FAR1 PF03101.10 EGO57416.1 - 0.00034 21.0 0.2 0.00034 21.0 0.1 3.0 3 0 0 3 3 3 1 FAR1 DNA-binding domain DUF853 PF05872.7 EGO57416.1 - 0.1 10.8 8.5 0.21 9.8 5.9 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) IncA PF04156.9 EGO57416.1 - 0.87 9.1 16.4 0.39 10.3 9.0 2.0 2 0 0 2 2 2 0 IncA protein PspA_IM30 PF04012.7 EGO57416.1 - 8.7 5.6 27.6 6.8 5.9 16.0 2.7 3 0 0 3 3 3 0 PspA/IM30 family Plasmodium_Vir PF05795.6 EGO57416.1 - 9.1 5.3 5.7 17 4.4 3.9 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Peptidase_M3_N PF08439.5 EGO57417.1 - 0.12 12.4 0.9 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 Oligopeptidase F Ribosomal_L34e PF01199.13 EGO57418.1 - 1.2e-37 128.0 4.0 1.6e-37 127.5 2.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 EGO57418.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) FhuF_C PF11575.3 EGO57418.1 - 0.88 9.2 6.0 2.5 7.8 0.2 2.8 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain DUF498 PF04430.9 EGO57419.1 - 9.1e-27 92.7 0.0 3.3e-26 90.9 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) CMAS PF02353.15 EGO57420.1 - 6.9e-64 215.5 0.1 8.9e-64 215.1 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EGO57420.1 - 1.1e-12 47.9 0.0 3.2e-12 46.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO57420.1 - 1.1e-08 35.4 0.0 2.3e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO57420.1 - 0.00042 19.9 0.0 0.00069 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO57420.1 - 0.00044 20.5 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO57420.1 - 0.00081 19.8 0.0 0.0016 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO57420.1 - 0.0017 18.3 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EGO57420.1 - 0.0094 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EGO57420.1 - 0.027 15.0 0.0 0.068 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EGO57420.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.14 EGO57420.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EGO57420.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Alpha-amylase PF00128.19 EGO57421.1 - 2.1e-100 336.1 0.1 3.1e-100 335.6 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_42C PF08533.5 EGO57421.1 - 0.0071 15.8 0.0 0.019 14.4 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain hDGE_amylase PF14701.1 EGO57421.1 - 0.028 13.3 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Sugar_tr PF00083.19 EGO57422.1 - 1.7e-68 231.3 19.2 2.1e-68 230.9 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO57422.1 - 7.7e-15 54.4 33.4 1.4e-09 37.1 10.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGO57422.1 - 0.5 8.7 28.8 0.76 8.0 3.3 3.4 1 1 2 3 3 3 0 MFS/sugar transport protein G-patch_2 PF12656.2 EGO57423.1 - 1.9e-15 56.4 0.1 1.6e-14 53.4 0.0 2.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site Myb_DNA-bind_6 PF13921.1 EGO57424.1 - 4.7e-15 55.4 0.2 1.8e-14 53.5 0.1 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGO57424.1 - 0.001 19.0 1.3 0.0018 18.2 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain WD40 PF00400.27 EGO57425.1 - 3.6e-14 51.9 0.0 0.018 14.9 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Sec10 PF07393.6 EGO57425.1 - 0.045 11.9 1.0 0.065 11.4 0.7 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Med3 PF11593.3 EGO57425.1 - 5.5 6.1 15.0 8 5.5 10.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal efThoc1 PF11957.3 EGO57426.1 - 8.6e-164 545.6 2.9 1.1e-163 545.3 2.0 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 EGO57426.1 - 2.5e-24 85.7 0.0 5.4e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Guanylate kinase AAA_12 PF13087.1 EGO57427.1 - 6.6e-26 90.9 0.0 1.1e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGO57427.1 - 7.1e-22 78.1 0.0 1.6e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO57427.1 - 9.4e-09 34.9 0.0 4.5e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EGO57427.1 - 8.4e-06 25.4 0.0 0.0034 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EGO57427.1 - 0.00042 20.1 0.0 0.0014 18.4 0.0 1.8 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EGO57427.1 - 0.0014 18.0 0.0 0.0036 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EGO57427.1 - 0.0017 18.5 0.0 0.0053 16.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EGO57427.1 - 0.0023 17.4 0.0 0.06 12.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Viral_helicase1 PF01443.13 EGO57427.1 - 0.0055 16.2 0.1 0.43 10.0 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EGO57427.1 - 0.0091 16.1 0.0 0.028 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGO57427.1 - 0.012 14.7 0.0 0.04 13.0 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EGO57427.1 - 0.013 15.4 0.0 0.056 13.4 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 EGO57427.1 - 0.033 13.1 0.8 0.06 12.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EGO57427.1 - 0.035 14.9 0.0 1.3 9.9 0.0 3.5 3 0 0 3 3 2 0 AAA domain Arch_ATPase PF01637.13 EGO57427.1 - 0.054 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase DnaB_C PF03796.10 EGO57427.1 - 0.14 10.9 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PIF1 PF05970.9 EGO57427.1 - 0.17 10.7 0.0 7 5.4 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase NB-ARC PF00931.17 EGO57427.1 - 0.18 10.6 0.0 0.34 9.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EGO57427.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 EGO57427.1 - 0.19 11.8 0.0 0.46 10.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RecA PF00154.16 EGO57427.1 - 0.22 10.5 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein MIF4G PF02854.14 EGO57429.1 - 1.7e-53 181.1 0.0 2.8e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EGO57429.1 - 2.5e-22 78.5 0.2 7.6e-22 76.9 0.2 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 HC2 PF07382.6 EGO57429.1 - 0.0022 17.9 50.0 0.0022 17.9 34.7 2.8 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 INSIG PF07281.7 EGO57430.1 - 2.3e-46 157.5 0.3 5.3e-45 153.1 0.2 2.6 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) DNA_pol_B PF00136.16 EGO57431.1 - 1.5e-112 376.7 2.4 1.5e-112 376.7 1.6 1.5 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EGO57431.1 - 3.2e-68 228.8 0.4 5.6e-68 228.0 0.3 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EGO57431.1 - 6.2e-40 137.0 0.0 9.6e-40 136.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EGO57431.1 - 6e-21 74.0 13.0 6e-21 74.0 9.0 2.8 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal PPR_2 PF13041.1 EGO57432.1 - 9.7e-23 79.8 0.7 3e-15 55.9 0.1 4.5 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.1 EGO57432.1 - 1.4e-08 34.3 2.5 0.019 15.2 0.0 5.3 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.15 EGO57432.1 - 6.5e-08 32.0 0.4 0.0002 21.1 0.1 4.9 4 0 0 4 4 4 1 PPR repeat PPR_1 PF12854.2 EGO57432.1 - 1.1e-05 24.7 0.0 0.024 14.1 0.0 4.2 4 0 0 4 4 4 1 PPR repeat Pkinase PF00069.20 EGO57433.1 - 8.1e-53 179.2 0.0 1.8e-52 178.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57433.1 - 1.9e-23 82.8 0.0 3.6e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO57433.1 - 0.00046 19.9 2.4 0.00079 19.2 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGO57433.1 - 0.0048 16.2 0.2 0.015 14.6 0.1 1.7 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 EGO57433.1 - 0.099 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) DUF2778 PF10908.3 EGO57434.1 - 0.011 15.9 0.0 0.012 15.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2778) DUF2171 PF09939.4 EGO57434.1 - 0.041 13.8 1.3 0.055 13.4 0.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2171) Med3 PF11593.3 EGO57434.1 - 0.091 11.9 1.8 0.091 11.9 1.2 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RRM_1 PF00076.17 EGO57435.1 - 1.3e-58 194.5 0.1 1.9e-21 75.4 0.0 4.2 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO57435.1 - 2.4e-42 142.7 0.4 3.1e-13 49.4 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO57435.1 - 7.1e-29 99.4 0.0 4.7e-10 39.1 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGO57435.1 - 1.6e-06 27.7 0.0 0.021 14.5 0.0 3.5 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif PH PF00169.24 EGO57437.1 - 1.8e-27 95.5 2.3 5.6e-16 58.6 0.1 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EGO57437.1 - 1e-11 45.0 4.8 2.1e-05 24.7 0.1 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 EGO57437.1 - 4.3e-10 39.7 3.2 1.9e-05 24.8 0.2 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 EGO57437.1 - 0.00068 19.6 0.1 0.002 18.1 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EGO57437.1 - 0.0011 18.8 1.1 0.024 14.5 0.2 2.4 2 0 0 2 2 2 1 PH domain DUF2392 PF10288.4 EGO57438.1 - 1.5e-18 67.1 0.0 1.7e-12 47.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2392) RRM_1 PF00076.17 EGO57439.1 - 7.7e-05 22.2 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO57439.1 - 0.00084 19.2 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO57439.1 - 0.0036 17.1 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelP_N PF04592.9 EGO57439.1 - 0.16 11.3 1.4 0.24 10.7 0.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Cation_efflux PF01545.16 EGO57440.1 - 3.5e-61 206.7 0.5 4.6e-61 206.3 0.3 1.1 1 0 0 1 1 1 1 Cation efflux family DUF555 PF04475.7 EGO57440.1 - 0.088 12.8 0.2 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF555) Pkinase PF00069.20 EGO57441.1 - 1.8e-61 207.5 0.0 3.4e-61 206.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57441.1 - 6.6e-30 104.0 0.0 1.4e-29 103.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO57441.1 - 0.0014 17.6 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGO57441.1 - 0.013 14.5 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO57441.1 - 0.047 13.4 2.3 0.28 10.8 1.6 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family YABBY PF04690.8 EGO57441.1 - 2.2 8.4 5.0 4.4 7.5 3.5 1.4 1 0 0 1 1 1 0 YABBY protein DUF3987 PF13148.1 EGO57441.1 - 4.1 5.8 12.2 5.6 5.4 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Rtf2 PF04641.7 EGO57441.1 - 8.3 5.5 15.1 15 4.6 10.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger eIF3_subunit PF08597.5 EGO57441.1 - 9.4 5.7 19.0 15 5.0 13.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RRM_6 PF14259.1 EGO57443.1 - 8.7e-05 22.4 0.1 0.00073 19.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.22 EGO57444.1 - 2.6e-58 193.7 4.4 1.2e-19 69.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 EGO57445.1 - 1.7e-15 56.2 0.3 2.5e-08 33.4 0.0 4.2 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EGO57445.1 - 0.15 11.7 0.1 2.7 7.6 0.0 2.7 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A SRP9-21 PF05486.7 EGO57446.1 - 2e-27 94.7 0.3 3.4e-27 94.0 0.2 1.4 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF3138 PF11336.3 EGO57446.1 - 0.26 9.4 3.8 0.41 8.7 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribonuc_red_sm PF00268.16 EGO57447.1 - 2.2e-120 400.8 1.1 2.7e-120 400.6 0.7 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Fib_succ_major PF09603.5 EGO57447.1 - 0.057 13.9 0.1 0.11 13.0 0.1 1.3 1 0 0 1 1 1 0 Fibrobacter succinogenes major domain (Fib_succ_major) DUF4112 PF13430.1 EGO57448.1 - 3.5e-35 120.1 0.9 4.6e-35 119.7 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DCP2 PF05026.8 EGO57449.1 - 2.7e-35 120.1 0.9 6.6e-35 118.8 0.6 1.7 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EGO57449.1 - 2e-15 56.6 0.0 4.2e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Transaldolase PF00923.14 EGO57449.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Transaldolase FGGY_C PF02782.11 EGO57450.1 - 4.7e-25 88.3 0.1 2.8e-24 85.8 0.0 2.2 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EGO57450.1 - 1.2e-20 73.8 0.0 1.4e-11 44.2 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain DUF2424 PF10340.4 EGO57451.1 - 4e-24 84.9 0.0 5.2e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EGO57451.1 - 5.2e-24 84.9 0.0 7.3e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold CBFD_NFYB_HMF PF00808.18 EGO57452.1 - 5.9e-13 48.6 1.3 1e-12 47.9 0.9 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGO57452.1 - 6.3e-05 23.0 0.4 0.00011 22.2 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Drf_FH1 PF06346.7 EGO57452.1 - 0.55 9.7 13.4 0.15 11.5 5.4 2.2 2 0 0 2 2 2 0 Formin Homology Region 1 AA_permease_2 PF13520.1 EGO57454.1 - 1.2e-86 290.9 27.5 1.6e-86 290.5 19.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO57454.1 - 3.4e-21 75.1 19.9 6.5e-21 74.2 13.7 1.4 1 1 1 2 2 2 1 Amino acid permease PI3_PI4_kinase PF00454.22 EGO57455.1 - 4.9e-32 111.2 0.0 8.5e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 EGO57455.1 - 2.2e-19 68.9 0.2 7e-19 67.3 0.1 2.0 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 Fungal_trans PF04082.13 EGO57456.1 - 1.4e-28 99.5 0.0 2.6e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO57456.1 - 2.8e-09 36.7 10.8 4.4e-09 36.1 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2132 PF09905.4 EGO57456.1 - 0.017 15.0 0.0 0.053 13.4 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2132) Kri1 PF05178.7 EGO57457.1 - 1.8e-27 95.5 23.6 1.8e-27 95.5 16.3 6.8 6 1 1 7 7 7 1 KRI1-like family Kri1_C PF12936.2 EGO57457.1 - 1.8e-25 88.6 0.8 1.8e-25 88.6 0.6 5.1 6 0 0 6 6 6 1 KRI1-like family C-terminal Ras PF00071.17 EGO57458.1 - 1.2e-57 193.8 0.0 1.5e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO57458.1 - 3.3e-20 72.7 0.0 5.3e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO57458.1 - 1.3e-13 50.5 0.0 2.1e-13 49.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGO57458.1 - 6e-06 25.8 0.0 1.5e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGO57458.1 - 7.2e-06 25.3 0.0 8.4e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGO57458.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EGO57458.1 - 0.0091 16.0 0.0 0.016 15.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO57458.1 - 0.074 13.1 0.0 0.23 11.6 0.0 1.8 2 1 0 2 2 2 0 AAA domain zf-C3HC4_3 PF13920.1 EGO57459.1 - 0.0008 19.0 11.1 0.0012 18.4 7.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGO57459.1 - 0.036 13.8 4.3 0.057 13.2 3.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EGO57459.1 - 0.25 11.0 12.6 0.39 10.4 8.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGO57459.1 - 0.98 9.4 12.8 1.5 8.9 8.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Septin PF00735.13 EGO57460.1 - 4.7e-18 65.2 0.0 4.9e-17 61.8 0.0 2.1 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EGO57460.1 - 4.3e-05 23.4 0.0 0.00019 21.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGO57460.1 - 0.00022 21.7 0.1 0.00053 20.4 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 EGO57460.1 - 0.0025 17.3 0.1 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF258 PF03193.11 EGO57460.1 - 0.0043 16.2 0.2 0.012 14.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGO57460.1 - 0.0054 16.5 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 Dynamin family AAA_16 PF13191.1 EGO57460.1 - 0.0074 16.2 0.2 0.024 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EGO57460.1 - 0.011 15.2 0.7 0.049 13.1 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EGO57460.1 - 0.012 15.2 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EGO57460.1 - 0.015 15.5 0.0 0.047 13.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EGO57460.1 - 0.017 15.4 0.0 0.054 13.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EGO57460.1 - 0.026 13.6 0.7 0.057 12.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 EGO57460.1 - 0.027 14.5 0.1 0.09 12.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EGO57460.1 - 0.048 12.5 0.1 0.1 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MCM PF00493.18 EGO57460.1 - 0.064 12.0 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family NACHT PF05729.7 EGO57460.1 - 0.068 12.8 0.1 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 EGO57460.1 - 0.074 13.3 0.4 0.17 12.1 0.3 1.7 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGO57460.1 - 0.087 12.5 0.1 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_17 PF13207.1 EGO57460.1 - 0.14 12.9 0.0 0.38 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EGO57460.1 - 0.15 11.5 0.0 0.36 10.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Gtr1_RagA PF04670.7 EGO57460.1 - 0.15 11.1 0.1 4.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region MobB PF03205.9 EGO57460.1 - 0.16 11.7 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DnaJ PF00226.26 EGO57461.1 - 8e-08 31.9 0.2 8e-08 31.9 0.2 2.4 2 0 0 2 2 2 1 DnaJ domain BBP1_C PF15272.1 EGO57461.1 - 0.01 15.3 2.4 0.01 15.3 1.7 2.3 2 1 0 2 2 2 0 Spindle pole body component BBP1, C-terminal HCMV_UL139 PF12507.3 EGO57461.1 - 3.1 7.9 13.0 0.084 13.0 1.9 2.8 2 1 0 2 2 2 0 Human Cytomegalovirus UL139 protein AvrE PF11725.3 EGO57461.1 - 5.9 3.7 21.2 7.2 3.4 14.7 1.0 1 0 0 1 1 1 0 Pathogenicity factor DIOX_N PF14226.1 EGO57462.1 - 1.2e-22 80.6 0.0 2.2e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGO57462.1 - 1.6e-19 69.9 0.0 2.4e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.9 EGO57463.1 - 1.5e-41 142.7 0.1 1.9e-41 142.4 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase Asparaginase PF00710.15 EGO57463.1 - 0.083 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Asparaginase DEAD PF00270.24 EGO57464.1 - 2.7e-39 134.3 0.0 7.1e-39 133.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO57464.1 - 1.5e-26 92.0 0.1 3.6e-26 90.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGO57464.1 - 0.012 14.4 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 EGO57464.1 - 0.079 12.7 0.0 0.39 10.5 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Nop14 PF04147.7 EGO57464.1 - 0.16 9.8 26.2 0.26 9.1 18.2 1.3 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 EGO57464.1 - 0.53 8.5 30.7 0.78 8.0 21.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TATR PF03430.8 EGO57464.1 - 4.1 5.9 7.6 6.2 5.3 5.3 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Pkinase PF00069.20 EGO57465.1 - 1.7e-61 207.6 0.0 2.1e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57465.1 - 2.7e-37 128.2 0.0 3.9e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO57465.1 - 5.1e-09 35.5 0.0 7.6e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGO57465.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF695 PF05117.7 EGO57466.1 - 0.032 14.1 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF695) DUF3439 PF11921.3 EGO57466.1 - 0.39 10.4 4.5 0.56 9.9 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Pkinase PF00069.20 EGO57467.1 - 3.7e-42 144.2 0.0 4.2e-40 137.5 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57467.1 - 1.4e-17 63.5 0.0 9.1e-17 60.9 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO57467.1 - 0.00014 20.9 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGO57467.1 - 0.0024 16.9 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EGO57467.1 - 0.03 13.1 0.0 0.038 12.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EGO57468.1 - 1.8e-31 109.2 7.0 1.5e-21 76.7 0.0 3.4 2 2 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57468.1 - 4.8e-19 68.4 3.7 9.3e-15 54.3 0.0 3.2 2 1 1 3 3 3 2 Protein tyrosine kinase ROS_MUCR PF05443.6 EGO57468.1 - 0.0001 22.0 3.7 0.00038 20.2 1.3 2.6 2 0 0 2 2 2 1 ROS/MUCR transcriptional regulator protein MAD PF05557.8 EGO57468.1 - 0.0062 14.6 33.9 0.009 14.1 23.5 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein zf-C2H2_2 PF12756.2 EGO57468.1 - 0.032 14.3 0.2 0.032 14.3 0.1 2.8 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) CAF-1_p150 PF11600.3 EGO57468.1 - 0.65 9.3 53.5 1.4 8.2 37.1 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 EGO57468.1 - 7.6 5.6 40.6 11 5.0 28.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pkinase PF00069.20 EGO57469.1 - 1.7e-40 138.8 0.0 1.5e-35 122.5 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57469.1 - 3.3e-24 85.3 0.0 4.9e-19 68.3 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGO57469.1 - 2e-06 26.9 0.0 2.5e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGO57469.1 - 0.00074 18.6 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO57469.1 - 0.02 14.6 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EGO57470.1 - 6e-05 22.2 0.3 0.00085 18.4 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGO57470.1 - 0.0015 17.7 0.0 0.003 16.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Rsm1 PF08600.5 EGO57470.1 - 0.031 14.1 0.1 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 Rsm1-like GCV_T PF01571.16 EGO57471.1 - 2.6e-18 66.1 0.0 4.6e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EGO57471.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Med3 PF11593.3 EGO57473.1 - 0.057 12.6 1.5 0.065 12.4 1.1 1.3 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal GCP5-Mod21 PF14609.1 EGO57473.1 - 0.17 9.9 3.1 0.22 9.5 2.2 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 zf-C2H2_2 PF12756.2 EGO57474.1 - 3.5e-08 33.4 6.3 0.0026 17.8 0.0 3.9 2 2 2 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EGO57474.1 - 1.3e-05 25.2 8.7 0.094 13.1 0.3 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO57474.1 - 0.00029 20.9 7.0 0.21 11.9 0.3 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 EGO57474.1 - 0.023 14.8 0.6 6.2 7.0 0.1 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding APG6 PF04111.7 EGO57474.1 - 0.21 10.6 23.1 0.3 10.0 16.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EGO57474.1 - 0.63 8.9 21.1 0.81 8.5 14.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Asp-B-Hydro_N PF05279.6 EGO57474.1 - 1.3 8.8 23.2 1.8 8.3 16.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region HlyD_2 PF12700.2 EGO57474.1 - 1.7 7.7 10.2 2.1 7.4 7.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein CemA PF03040.9 EGO57474.1 - 2.8 7.5 5.2 3.9 7.0 3.6 1.2 1 0 0 1 1 1 0 CemA family zf-C2H2_6 PF13912.1 EGO57474.1 - 3 7.8 7.4 12 6.0 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DUF940 PF06082.6 EGO57474.1 - 5.1 5.5 6.3 6.6 5.1 4.4 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) PLRV_ORF5 PF01690.12 EGO57474.1 - 8.6 5.3 12.4 11 5.0 8.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Pkinase PF00069.20 EGO57475.1 - 2.6e-42 144.7 0.0 7.1e-38 130.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57475.1 - 2.7e-20 72.5 0.0 2.2e-17 62.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EGO57475.1 - 0.0005 19.1 0.0 0.00073 18.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGO57475.1 - 0.0026 16.7 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO57475.1 - 0.11 12.2 0.1 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Phage_Treg PF04761.7 EGO57475.1 - 0.13 12.0 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator TruD PF01142.13 EGO57476.1 - 6.2e-54 183.1 0.1 3e-50 170.9 0.0 3.2 3 0 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) CH PF00307.26 EGO57477.1 - 1.9e-38 130.8 0.1 8.1e-19 67.6 0.0 3.2 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EGO57477.1 - 6.2e-26 90.1 0.1 2e-25 88.5 0.1 2.0 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EGO57477.1 - 3.3e-10 39.4 0.6 7e-07 28.8 0.0 3.2 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 EGO57477.1 - 6.4e-05 22.5 0.5 0.0018 17.9 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 EGO57477.1 - 0.00034 20.1 0.7 0.0057 16.2 0.1 2.8 2 1 1 3 3 3 1 EF-hand domain pair Spectrin PF00435.16 EGO57477.1 - 0.0014 18.8 0.9 1.4 9.2 0.1 2.8 2 0 0 2 2 2 2 Spectrin repeat EF-hand_1 PF00036.27 EGO57477.1 - 0.0027 16.8 0.2 0.048 12.9 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EGO57477.1 - 0.0064 16.5 1.6 0.0064 16.5 1.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair Sipho_Gp157 PF05565.6 EGO57477.1 - 0.14 11.7 0.9 0.84 9.2 0.1 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 Glyco_transf_90 PF05686.7 EGO57478.1 - 4e-15 55.4 9.7 1.2e-11 43.9 5.6 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF1183 PF06682.7 EGO57478.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Ribosomal_S8 PF00410.14 EGO57479.1 - 2.3e-26 92.1 0.1 3.1e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L7Ae PF01248.21 EGO57480.1 - 1.4e-28 98.2 0.8 1.7e-28 97.9 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 EGO57480.1 - 0.074 12.6 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Rotamase_3 PF13616.1 EGO57481.1 - 3.5e-19 69.1 0.1 6.1e-19 68.4 0.1 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EGO57481.1 - 8.2e-19 68.1 0.1 1.4e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EGO57481.1 - 3.6e-07 30.8 0.2 6.5e-07 30.0 0.0 1.5 1 1 1 2 2 2 1 PPIC-type PPIASE domain NfrA_C PF13283.1 EGO57482.1 - 0.026 13.9 0.2 0.04 13.2 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term Guanylate_cyc PF00211.15 EGO57482.1 - 0.11 11.9 0.3 0.17 11.1 0.2 1.2 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain DAGK_cat PF00781.19 EGO57482.1 - 0.13 11.6 0.2 0.39 10.1 0.0 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain VPS9 PF02204.13 EGO57483.1 - 2.1e-23 82.3 0.0 3.6e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Lipase_3 PF01764.20 EGO57484.1 - 5.6e-08 32.4 0.0 1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGO57484.1 - 0.0018 18.0 0.0 0.0066 16.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO57484.1 - 0.0092 15.8 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 EGO57484.1 - 0.074 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) zf-C3HC4 PF00097.20 EGO57485.1 - 1.3e-06 27.9 2.7 1.3e-06 27.9 1.9 5.4 7 0 0 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO57485.1 - 7.9e-05 22.5 2.5 7.9e-05 22.5 1.7 5.2 4 4 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGO57485.1 - 0.015 15.0 0.2 0.015 15.0 0.2 3.3 3 0 0 3 3 3 0 zf-RING of BARD1-type protein DUF3292 PF11696.3 EGO57485.1 - 0.026 12.3 7.2 0.52 8.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) SH3_9 PF14604.1 EGO57485.1 - 0.059 12.9 0.2 0.059 12.9 0.1 2.2 2 0 0 2 2 2 0 Variant SH3 domain Gly-zipper_OmpA PF13436.1 EGO57485.1 - 0.77 9.4 4.7 2.2 7.9 3.3 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Helicase_C_3 PF13625.1 EGO57486.1 - 5.4e-26 90.8 0.0 5.2e-25 87.6 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO57486.1 - 1.5e-16 60.7 0.0 4.3e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EGO57486.1 - 7.9e-11 41.2 0.0 1.2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO57486.1 - 4.5e-10 39.2 0.0 1.2e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CHY PF05495.7 EGO57487.1 - 1.9e-14 53.5 18.9 2.7e-14 53.0 13.1 1.2 1 0 0 1 1 1 1 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 EGO57487.1 - 0.0019 17.9 10.7 0.068 12.9 5.1 2.5 2 1 0 2 2 2 2 Transposase zinc-ribbon domain Cys_rich_KTR PF14205.1 EGO57487.1 - 0.21 11.0 9.0 25 4.4 3.7 2.6 1 1 1 2 2 2 0 Cysteine-rich KTR zinc_ribbon_2 PF13240.1 EGO57487.1 - 0.55 9.7 0.1 0.55 9.7 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-UDP PF14569.1 EGO57487.1 - 0.74 9.6 6.6 0.32 10.7 2.6 1.8 1 1 1 2 2 2 0 Zinc-binding RING-finger C1_4 PF07975.7 EGO57487.1 - 1.5 8.8 13.8 1.3 9.0 3.8 2.7 1 1 2 3 3 3 0 TFIIH C1-like domain HypA PF01155.14 EGO57487.1 - 2 8.1 11.8 29 4.3 8.2 2.2 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 EGO57487.1 - 2.2 7.5 13.5 5e+02 0.0 9.3 2.7 1 1 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 EGO57487.1 - 6.1 6.7 14.2 68 3.3 9.8 2.6 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EGO57487.1 - 6.9 6.7 20.7 3.6 7.6 6.5 2.5 2 1 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 EGO57487.1 - 8.8 6.1 14.2 2.9 7.6 5.7 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 EGO57487.1 - 9.5 5.8 15.1 17 5.0 0.1 3.9 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGO57487.1 - 9.8 5.9 15.7 15 5.3 0.1 3.9 3 1 0 3 3 3 0 zinc-ribbon domain Proteasome PF00227.21 EGO57488.1 - 3.6e-55 186.2 0.1 5.5e-55 185.5 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGO57488.1 - 1.8e-12 46.3 0.1 1.8e-12 46.3 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FAD-oxidase_C PF02913.14 EGO57489.1 - 3.1e-58 197.0 0.0 4.1e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGO57489.1 - 1.1e-37 128.6 0.2 2.3e-37 127.5 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain PSII_Pbs27 PF13326.1 EGO57489.1 - 0.064 13.2 0.1 0.59 10.1 0.0 2.3 3 0 0 3 3 3 0 Photosystem II Pbs27 Glyoxalase_2 PF12681.2 EGO57490.1 - 0.028 15.0 0.1 0.11 13.0 0.1 2.0 2 1 0 2 2 2 0 Glyoxalase-like domain Voltage_CLC PF00654.15 EGO57491.1 - 2.3e-90 303.1 26.7 2.3e-90 303.1 18.5 1.9 3 0 0 3 3 3 1 Voltage gated chloride channel CBS PF00571.23 EGO57491.1 - 2.6e-05 23.8 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 2 CBS domain Paf1 PF03985.8 EGO57492.1 - 4.3e-55 187.1 4.9 1.1e-54 185.8 3.4 1.6 1 1 0 1 1 1 1 Paf1 Cylicin_N PF15241.1 EGO57492.1 - 0.024 14.4 0.6 0.064 13.1 0.4 1.6 1 0 0 1 1 1 0 Cylicin N-terminus Rer1 PF03248.8 EGO57493.1 - 1.8e-81 271.9 5.6 2.1e-81 271.7 3.9 1.0 1 0 0 1 1 1 1 Rer1 family FA_desaturase PF00487.19 EGO57493.1 - 0.72 9.2 7.1 1.5 8.2 0.9 2.1 2 0 0 2 2 2 0 Fatty acid desaturase ECH PF00378.15 EGO57494.1 - 2.8e-70 236.2 0.1 3.5e-70 235.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EGO57494.1 - 0.035 14.2 0.1 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region TrkH PF02386.11 EGO57495.1 - 1.9e-124 414.8 17.2 2.5e-121 404.5 6.7 2.1 2 0 0 2 2 2 2 Cation transport protein Ribosomal_L19 PF01245.15 EGO57496.1 - 5e-18 64.9 0.1 8.2e-18 64.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 PALP PF00291.20 EGO57498.1 - 3.2e-62 210.5 0.1 3.8e-62 210.2 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme YL1 PF05764.8 EGO57499.1 - 1.3e-62 211.6 25.5 1.3e-62 211.6 17.7 4.4 4 0 0 4 4 4 1 YL1 nuclear protein YL1_C PF08265.6 EGO57499.1 - 3.3e-08 32.9 1.3 6e-08 32.1 0.9 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Ras PF00071.17 EGO57500.1 - 7.9e-52 174.9 0.0 9.2e-52 174.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO57500.1 - 8.4e-16 58.5 0.0 1.3e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO57500.1 - 2.7e-08 33.2 0.0 3.9e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RVT_1 PF00078.22 EGO57502.1 - 0.007 15.7 0.5 0.007 15.7 0.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF830 PF05708.7 EGO57502.1 - 0.08 12.9 1.3 0.089 12.7 0.9 1.0 1 0 0 1 1 1 0 Orthopoxvirus protein of unknown function (DUF830) ATP-synt_D PF01813.12 EGO57504.1 - 0.13 11.7 0.1 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 ATP synthase subunit D Arginase PF00491.16 EGO57505.1 - 9.4e-76 254.7 0.1 4.1e-74 249.3 0.1 2.0 1 1 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EGO57505.1 - 0.061 13.5 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain tRNA-synt_2 PF00152.15 EGO57506.1 - 9e-71 238.3 0.1 9e-71 238.3 0.1 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGO57506.1 - 1.9e-07 30.8 0.0 4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF342 PF03961.8 EGO57506.1 - 0.019 13.4 3.3 0.031 12.7 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) KfrA_N PF11740.3 EGO57506.1 - 0.03 14.7 3.5 0.066 13.6 2.4 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term tRNA-synt_2d PF01409.15 EGO57506.1 - 0.042 13.0 0.1 0.25 10.5 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) V_ATPase_I PF01496.14 EGO57506.1 - 0.08 10.7 0.6 0.13 10.0 0.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2681 PF10883.3 EGO57506.1 - 0.26 11.5 6.0 0.61 10.3 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF4407 PF14362.1 EGO57506.1 - 1.8 7.4 7.1 2.9 6.7 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RRM_6 PF14259.1 EGO57509.1 - 1.3e-40 137.1 0.0 3.1e-11 43.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO57509.1 - 1.6e-37 126.9 0.1 2.3e-11 43.1 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO57509.1 - 3.7e-20 71.5 0.1 0.00022 20.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EGO57509.1 - 6.7e-11 41.6 5.4 6.7e-11 41.6 3.7 3.1 3 1 0 3 3 3 1 Putative RRM domain RRM_3 PF08777.6 EGO57509.1 - 0.00012 21.8 0.2 0.017 14.9 0.1 2.5 2 0 0 2 2 2 1 RNA binding motif RNA_bind PF08675.6 EGO57509.1 - 0.013 15.4 0.1 0.2 11.6 0.0 2.8 3 1 0 3 3 3 0 RNA binding domain DUF4523 PF15023.1 EGO57509.1 - 0.088 12.3 0.0 2.9 7.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.1 EGO57509.1 - 0.15 11.8 0.1 20 5.0 0.0 3.2 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif His_Phos_2 PF00328.17 EGO57510.1 - 1.1e-23 84.0 0.0 9.8e-23 81.0 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPR_2 PF13041.1 EGO57511.1 - 4.5e-21 74.5 0.1 5e-10 39.2 0.0 5.3 4 0 0 4 4 4 3 PPR repeat family PPR_3 PF13812.1 EGO57511.1 - 1.6e-11 43.4 6.5 0.0083 16.3 0.0 8.3 7 1 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 EGO57511.1 - 3.5e-11 42.3 5.5 0.026 14.5 0.0 6.2 6 0 0 6 6 6 4 PPR repeat PPR_1 PF12854.2 EGO57511.1 - 8.2e-09 34.8 0.0 3.5e-05 23.1 0.0 5.1 5 0 0 5 5 5 1 PPR repeat ECSIT PF06239.6 EGO57511.1 - 0.0018 17.2 0.1 1.7 7.4 0.0 3.9 2 1 1 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_14 PF13428.1 EGO57511.1 - 3.3 8.6 8.2 58 4.7 1.1 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_60s PF00428.14 EGO57512.1 - 1.6 9.1 4.8 6.3 7.2 3.3 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Mis12 PF05859.7 EGO57513.1 - 3.1e-45 153.5 1.5 3.5e-45 153.3 0.0 1.8 2 0 0 2 2 2 1 Mis12 protein TCTP PF00838.12 EGO57514.1 - 7.4e-63 211.4 3.8 8.3e-63 211.2 2.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein SIMPL PF04402.9 EGO57514.1 - 0.052 13.4 1.9 0.46 10.3 1.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF541) FA_hydroxylase PF04116.8 EGO57515.1 - 1.3e-16 61.0 10.7 2.5e-16 60.0 7.4 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily PHO4 PF01384.15 EGO57515.1 - 0.07 11.7 0.1 0.082 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphate transporter family AAA_5 PF07728.9 EGO57517.1 - 6.3e-117 385.5 0.0 7.8e-22 77.4 0.0 8.7 8 0 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGO57517.1 - 1.5e-27 95.7 0.0 1.3e-09 37.7 0.0 5.9 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EGO57517.1 - 1.7e-24 86.4 0.0 5.1e-05 23.4 0.0 6.1 5 0 0 5 5 5 5 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGO57517.1 - 1.3e-23 83.9 22.7 2.6e-05 24.2 0.0 9.1 8 0 0 8 8 7 4 AAA ATPase domain AAA_17 PF13207.1 EGO57517.1 - 6.8e-23 81.7 0.0 0.003 18.3 0.0 7.6 5 1 1 6 6 5 5 AAA domain AAA_33 PF13671.1 EGO57517.1 - 4.9e-20 71.8 0.0 0.0041 17.0 0.0 6.8 5 0 0 5 5 5 4 AAA domain AAA_14 PF13173.1 EGO57517.1 - 6.7e-20 71.2 0.0 0.00015 21.6 0.0 7.3 8 0 0 8 8 6 4 AAA domain AAA_22 PF13401.1 EGO57517.1 - 1.1e-19 70.9 7.0 0.0097 16.0 0.0 8.9 9 1 0 9 9 8 5 AAA domain Sigma54_activat PF00158.21 EGO57517.1 - 8.7e-16 57.8 0.0 0.025 14.0 0.0 5.8 5 0 0 5 5 5 4 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EGO57517.1 - 2.2e-15 56.9 1.1 4.5e-05 23.5 0.1 6.3 6 0 0 6 6 5 3 Sigma-54 interaction domain AAA_18 PF13238.1 EGO57517.1 - 2.3e-15 57.0 5.5 0.017 15.4 0.0 6.8 6 0 0 6 6 5 4 AAA domain T2SE PF00437.15 EGO57517.1 - 3.3e-13 49.1 0.2 0.034 13.0 0.0 5.7 5 0 0 5 5 5 3 Type II/IV secretion system protein NACHT PF05729.7 EGO57517.1 - 5.3e-13 48.9 1.8 0.058 13.0 0.1 5.3 5 0 0 5 5 4 4 NACHT domain DUF258 PF03193.11 EGO57517.1 - 6.4e-13 48.1 0.3 0.034 13.3 0.1 5.3 5 0 0 5 5 5 4 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EGO57517.1 - 1.1e-12 48.2 0.0 0.0014 18.4 0.0 5.8 5 0 0 5 5 5 2 Archaeal ATPase RNA_helicase PF00910.17 EGO57517.1 - 3.3e-11 43.3 0.2 1 9.5 0.0 5.7 5 0 0 5 5 5 2 RNA helicase UPF0079 PF02367.12 EGO57517.1 - 1.8e-10 40.5 1.7 0.14 11.8 0.0 4.7 4 0 0 4 4 4 3 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EGO57517.1 - 3.4e-10 40.1 0.6 0.87 9.5 0.0 6.2 5 0 0 5 5 5 2 AAA domain AAA_19 PF13245.1 EGO57517.1 - 5.2e-10 38.9 6.0 0.016 14.9 0.2 5.7 5 0 0 5 5 5 2 Part of AAA domain MobB PF03205.9 EGO57517.1 - 6.3e-10 38.9 0.6 2 8.1 0.0 5.6 5 0 0 5 5 5 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EGO57517.1 - 6.4e-10 38.4 0.1 0.28 10.7 0.0 5.5 5 0 0 5 5 5 2 P-loop containing region of AAA domain Mg_chelatase PF01078.16 EGO57517.1 - 1.3e-09 37.5 1.1 0.48 9.5 0.0 7.0 7 0 0 7 7 7 2 Magnesium chelatase, subunit ChlI Miro PF08477.8 EGO57517.1 - 2.1e-09 37.9 0.8 8.5 6.8 0.0 6.2 5 0 0 5 5 5 0 Miro-like protein IstB_IS21 PF01695.12 EGO57517.1 - 4.7e-09 35.9 0.2 0.45 9.9 0.0 5.3 5 0 0 5 5 5 2 IstB-like ATP binding protein ABC_tran PF00005.22 EGO57517.1 - 8.6e-09 35.8 16.0 0.12 12.6 0.0 7.8 8 0 0 8 8 6 3 ABC transporter AAA_25 PF13481.1 EGO57517.1 - 2.6e-08 33.4 0.7 0.98 8.7 0.0 5.5 4 0 0 4 4 4 2 AAA domain NTPase_1 PF03266.10 EGO57517.1 - 1.4e-06 28.1 1.5 0.84 9.3 0.0 4.7 4 0 0 4 4 4 2 NTPase SRP54 PF00448.17 EGO57517.1 - 1.7e-06 27.6 1.2 0.77 9.1 0.0 5.2 5 0 0 5 5 5 2 SRP54-type protein, GTPase domain cobW PF02492.14 EGO57517.1 - 3.5e-06 26.5 3.0 2.9 7.2 0.0 5.6 5 0 0 5 5 5 1 CobW/HypB/UreG, nucleotide-binding domain RuvB_N PF05496.7 EGO57517.1 - 4.3e-06 25.9 4.9 2 7.4 0.0 5.9 7 0 0 7 7 7 2 Holliday junction DNA helicase ruvB N-terminus MMR_HSR1 PF01926.18 EGO57517.1 - 3e-05 23.9 0.8 10 6.1 0.0 5.7 5 0 0 5 5 5 0 50S ribosome-binding GTPase TIP49 PF06068.8 EGO57517.1 - 0.00012 20.9 0.4 1.9 7.0 0.0 4.5 6 0 0 6 6 6 1 TIP49 C-terminus PduV-EutP PF10662.4 EGO57517.1 - 0.0012 18.2 2.0 4.5 6.7 0.0 4.9 5 0 0 5 5 5 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EGO57517.1 - 0.0013 18.2 0.7 30 4.0 0.0 4.9 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 EGO57517.1 - 0.002 17.6 0.0 5.7 6.3 0.0 4.2 5 0 0 5 5 4 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 EGO57517.1 - 0.0036 16.0 1.4 0.52 8.9 0.0 4.2 5 0 0 5 5 5 1 Rad17 cell cycle checkpoint protein CbiA PF01656.18 EGO57517.1 - 0.0053 16.1 0.1 3.8 6.8 0.0 4.3 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.15 EGO57517.1 - 0.0096 15.5 0.3 1.3 8.6 0.0 4.2 5 0 0 5 5 4 1 Adenylylsulphate kinase AAA_7 PF12775.2 EGO57517.1 - 0.05 12.6 0.3 22 4.0 0.0 3.8 4 0 0 4 4 4 0 P-loop containing dynein motor region D3 KaiC PF06745.8 EGO57517.1 - 0.079 12.0 0.2 26 3.8 0.0 3.7 3 0 0 3 3 3 0 KaiC AAA_6 PF12774.2 EGO57517.1 - 0.1 12.0 0.0 70 2.8 0.0 4.5 7 0 0 7 7 5 0 Hydrolytic ATP binding site of dynein motor region D1 Ribosomal_L12 PF00542.14 EGO57518.1 - 4.3e-20 71.4 7.1 3.3e-19 68.6 3.8 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain PP2C_C PF07830.8 EGO57518.1 - 0.35 10.9 2.3 6.5 6.9 0.0 2.7 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain CTK3 PF12243.3 EGO57519.1 - 1.2e-57 193.3 0.4 2e-57 192.6 0.3 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EGO57519.1 - 3.2e-18 65.5 11.2 7.4e-18 64.3 7.8 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Imm1 PF14430.1 EGO57519.1 - 0.012 15.7 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Immunity protein Imm1 P5CR_dimer PF14748.1 EGO57520.1 - 1.4e-33 115.0 3.8 2.8e-33 114.1 2.6 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EGO57520.1 - 4.5e-07 30.2 3.7 1.9e-05 25.0 2.1 3.2 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Hat1_N PF10394.4 EGO57521.1 - 3.3e-41 141.0 0.4 1.1e-40 139.2 0.1 1.9 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.19 EGO57521.1 - 0.0089 16.0 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGO57521.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Zip PF02535.17 EGO57522.1 - 1.4e-37 129.4 15.9 1.8e-35 122.5 11.0 2.4 1 1 0 1 1 1 1 ZIP Zinc transporter PYST-C1 PF09690.5 EGO57523.1 - 0.11 12.1 0.2 0.35 10.5 0.1 1.8 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) IR1-M PF12185.3 EGO57524.1 - 0.068 12.9 0.3 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain DUF678 PF05077.7 EGO57525.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF678) SulA PF03846.9 EGO57527.1 - 0.098 12.3 2.0 0.17 11.5 1.4 1.4 1 0 0 1 1 1 0 Cell division inhibitor SulA Methyltransf_23 PF13489.1 EGO57531.1 - 4.3e-16 59.0 0.0 6.6e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO57531.1 - 3.4e-08 33.8 0.0 6.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO57531.1 - 2.1e-07 31.4 0.1 3.5e-06 27.5 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO57531.1 - 1.3e-05 25.5 0.0 0.0001 22.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO57531.1 - 2.5e-05 23.9 0.0 0.00054 19.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO57531.1 - 0.00023 20.3 0.2 0.0047 16.0 0.1 2.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EGO57531.1 - 0.011 14.8 0.0 0.022 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.4 EGO57531.1 - 0.022 14.2 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 EGO57531.1 - 0.028 14.3 0.6 0.27 11.1 0.4 2.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EGO57531.1 - 0.033 14.5 0.0 0.084 13.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EGO57531.1 - 0.05 12.7 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) HET PF06985.6 EGO57532.1 - 4.9e-26 91.5 0.0 9.4e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DNA_ligase_A_M PF01068.16 EGO57534.1 - 4.7e-57 192.6 0.2 4.9e-55 186.0 0.1 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGO57534.1 - 6.5e-50 169.3 0.1 1.9e-49 167.8 0.0 1.9 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGO57534.1 - 1.2e-28 99.3 1.3 2.7e-28 98.1 0.0 2.3 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EGO57534.1 - 0.021 14.4 0.0 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain CDC45 PF02724.9 EGO57534.1 - 0.44 8.5 5.2 0.65 7.9 3.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EGO57534.1 - 6.1 4.6 13.6 1.5 6.6 7.2 1.4 2 0 0 2 2 2 0 Nop14-like family E1_dh PF00676.15 EGO57535.1 - 2.8e-113 377.5 0.2 3.3e-113 377.3 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EGO57535.1 - 0.0027 16.7 0.4 0.0053 15.7 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase WD40 PF00400.27 EGO57536.1 - 2.3e-52 173.1 21.2 2.5e-10 39.8 0.3 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EGO57536.1 - 2.6e-14 52.6 0.4 5.1e-14 51.7 0.3 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EGO57536.1 - 5e-09 34.8 15.6 0.024 12.7 0.2 5.9 2 1 3 6 6 6 5 Nucleoporin Nup120/160 F-box PF00646.28 EGO57536.1 - 9.9e-06 25.0 1.9 2.4e-05 23.8 1.3 1.7 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 EGO57536.1 - 0.98 9.7 6.6 24 5.3 0.1 4.9 4 1 1 5 5 5 0 PQQ-like domain AAA PF00004.24 EGO57537.1 - 2.6e-50 170.0 0.0 4.4e-42 143.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EGO57537.1 - 5e-06 26.0 0.0 5.1e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 EGO57537.1 - 8.6e-06 25.8 0.0 8.7e-05 22.5 0.0 2.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EGO57537.1 - 2.4e-05 24.3 0.0 6.6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGO57537.1 - 8.6e-05 22.6 0.0 0.0027 17.8 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGO57537.1 - 0.0015 18.2 0.1 0.0099 15.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.20 EGO57537.1 - 0.0028 17.5 0.0 0.0099 15.7 0.0 1.9 1 0 0 1 1 1 1 Bromodomain AAA_33 PF13671.1 EGO57537.1 - 0.0029 17.4 0.0 0.013 15.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO57537.1 - 0.0076 16.5 0.2 0.062 13.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EGO57537.1 - 0.01 14.5 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_17 PF13207.1 EGO57537.1 - 0.011 16.4 1.6 0.03 15.1 0.0 2.6 3 0 0 3 3 1 0 AAA domain RNA_helicase PF00910.17 EGO57537.1 - 0.012 15.7 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.7 EGO57537.1 - 0.016 14.2 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 EGO57537.1 - 0.018 15.0 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 EGO57537.1 - 0.022 14.6 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGO57537.1 - 0.078 12.6 0.1 0.25 10.9 0.1 1.9 1 1 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 EGO57537.1 - 5.3 6.1 8.0 0.16 11.1 0.1 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_pol_I_A49 PF06870.7 EGO57538.1 - 5.2e-105 351.1 3.7 6.8e-105 350.8 2.6 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Arfaptin PF06456.8 EGO57538.1 - 0.1 11.9 4.4 5.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Arfaptin-like domain Pkinase PF00069.20 EGO57541.1 - 7.4e-59 198.9 0.0 1e-58 198.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57541.1 - 1.7e-23 83.0 0.0 1.8e-22 79.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.21 EGO57541.1 - 5.8e-13 48.7 0.5 1.7e-12 47.2 0.4 1.9 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EGO57541.1 - 1e-05 24.6 0.0 0.029 13.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like zf-C2H2_4 PF13894.1 EGO57542.1 - 4.7e-07 29.6 11.3 0.0007 19.7 1.9 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO57542.1 - 2.3e-06 27.6 10.3 0.0055 16.9 1.2 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO57542.1 - 0.013 15.7 12.8 1.3 9.4 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zf-Di19 PF05605.7 EGO57542.1 - 0.33 11.1 6.0 0.25 11.5 0.7 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SNF2_N PF00176.18 EGO57543.1 - 1.8e-83 279.8 1.1 1.8e-83 279.8 0.7 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EGO57543.1 - 7.9e-19 67.3 0.0 2.4e-18 65.8 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EGO57543.1 - 4.3e-17 61.7 5.5 7.8e-17 60.9 0.0 3.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain SnAC PF14619.1 EGO57543.1 - 5.5e-17 61.7 0.7 5.5e-17 61.7 0.5 3.9 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EGO57543.1 - 2.3e-14 52.9 11.9 2.3e-14 52.9 8.3 4.7 4 1 1 5 5 5 1 HSA QLQ PF08880.6 EGO57543.1 - 2.8e-10 39.4 2.9 2.8e-10 39.4 2.0 2.4 2 0 0 2 2 2 1 QLQ WD40 PF00400.27 EGO57545.1 - 3.1e-23 80.7 12.9 1.1e-07 31.4 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF2457 PF10446.4 EGO57545.1 - 0.00081 18.2 7.8 0.0017 17.2 5.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 EGO57545.1 - 0.022 12.7 4.3 0.029 12.2 3.0 1.2 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.5 EGO57545.1 - 0.073 13.0 3.3 0.14 12.1 2.3 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.1 EGO57545.1 - 0.18 11.4 4.8 0.37 10.4 3.3 1.4 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.7 EGO57545.1 - 0.3 10.7 11.1 0.64 9.6 7.7 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein EBV-NA3 PF05009.7 EGO57545.1 - 1.2 8.3 3.5 2.3 7.4 2.4 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PBP1_TM PF14812.1 EGO57545.1 - 1.5 9.1 16.5 4.6 7.6 11.4 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CobT PF06213.7 EGO57545.1 - 1.6 7.8 11.8 2.7 7.0 8.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tom22 PF04281.8 EGO57545.1 - 2.5 7.6 7.1 4.5 6.7 4.9 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 RXT2_N PF08595.6 EGO57545.1 - 3 7.6 8.1 6.6 6.5 5.6 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.5 EGO57545.1 - 3 8.1 14.2 6.5 7.0 9.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EGO57545.1 - 3.6 7.0 13.4 7.8 6.0 9.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EGO57545.1 - 4.8 6.7 14.1 4.3 6.8 7.2 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.9 EGO57545.1 - 6.6 4.6 9.1 11 3.9 6.3 1.2 1 0 0 1 1 1 0 CDC45-like protein PhyH PF05721.8 EGO57546.1 - 0.00063 19.8 0.1 0.0015 18.6 0.1 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3050 PF11251.3 EGO57546.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) BCNT PF07572.7 EGO57547.1 - 9.4e-25 86.3 4.1 2.1e-24 85.2 2.8 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development G-alpha PF00503.15 EGO57550.1 - 7.3e-134 446.3 1.3 8.9e-134 446.0 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGO57550.1 - 2e-15 56.4 1.4 2.3e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EGO57550.1 - 9.5e-05 21.8 0.0 0.00041 19.8 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EGO57550.1 - 0.0014 19.1 0.1 3 8.3 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EGO57550.1 - 0.0049 16.0 2.7 0.27 10.3 0.0 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EGO57550.1 - 0.011 15.1 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EGO57550.1 - 0.033 13.6 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.18 EGO57550.1 - 0.06 12.1 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family FtsK_SpoIIIE PF01580.13 EGO57550.1 - 0.075 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EGO57550.1 - 0.11 12.4 0.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DSBA PF01323.15 EGO57551.1 - 4.6e-12 45.8 0.0 2.3e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Serglycin PF04360.7 EGO57551.1 - 0.0068 16.1 3.5 0.017 14.8 2.4 1.6 1 0 0 1 1 1 1 Serglycin TMEM154 PF15102.1 EGO57551.1 - 0.015 14.9 0.2 0.03 14.0 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF543 PF04418.7 EGO57552.1 - 3.3e-29 100.6 0.1 3.6e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF2456 PF10445.4 EGO57552.1 - 0.14 12.0 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) Urb2 PF10441.4 EGO57553.1 - 1.2e-67 227.8 1.1 1.2e-67 227.8 0.7 2.7 3 0 0 3 3 3 1 Urb2/Npa2 family DUF577 PF04510.7 EGO57553.1 - 0.0058 16.3 0.2 0.97 9.1 0.0 3.3 3 0 0 3 3 3 2 Family of unknown function (DUF577) D123 PF07065.9 EGO57554.1 - 5.6e-77 258.7 0.0 2.3e-72 243.5 0.0 3.1 1 1 1 2 2 2 2 D123 RNA_polI_A34 PF08208.6 EGO57554.1 - 0.13 11.8 0.6 0.27 10.8 0.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 cwf21 PF08312.7 EGO57555.1 - 9.6e-18 63.7 14.9 9.6e-18 63.7 10.4 1.9 2 0 0 2 2 2 1 cwf21 domain HTH_28 PF13518.1 EGO57556.1 - 0.0031 17.4 0.0 4.9 7.2 0.0 4.1 4 0 0 4 4 4 1 Helix-turn-helix domain HTH_30 PF13556.1 EGO57556.1 - 0.0084 15.6 0.1 38 3.9 0.0 4.1 3 1 1 4 4 4 0 PucR C-terminal helix-turn-helix domain HTH_23 PF13384.1 EGO57556.1 - 0.015 14.9 0.1 1.7 8.3 0.0 3.5 3 0 0 3 3 3 0 Homeodomain-like domain HTH_11 PF08279.7 EGO57556.1 - 0.031 13.9 0.0 14 5.3 0.0 3.6 3 1 1 4 4 4 0 HTH domain HTH_psq PF05225.11 EGO57556.1 - 0.15 11.6 8.8 2.1 7.9 0.0 5.4 5 1 2 7 7 7 0 helix-turn-helix, Psq domain RasGEF PF00617.14 EGO57558.1 - 4.7e-61 205.8 0.1 1.1e-60 204.6 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGO57558.1 - 4.1e-25 87.9 1.2 1e-24 86.6 0.8 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EGO57558.1 - 6e-16 57.5 0.1 1.3e-15 56.4 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGO57558.1 - 2.5e-14 52.5 0.2 6e-14 51.3 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGO57558.1 - 1.6e-13 49.9 0.1 3.7e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EGO57558.1 - 0.069 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 WW domain Ser_hydrolase PF06821.8 EGO57558.1 - 0.08 12.5 0.3 0.15 11.6 0.2 1.4 1 0 0 1 1 1 0 Serine hydrolase Fungal_trans PF04082.13 EGO57561.1 - 2.5e-15 56.0 0.8 3.9e-15 55.4 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EGO57561.1 - 5.8e-07 29.4 13.2 0.0001 22.3 4.0 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO57561.1 - 8e-05 22.6 12.7 0.0082 16.4 3.3 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO57561.1 - 0.00086 19.5 13.4 0.2 12.0 3.3 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type Glyco_hydro_16 PF00722.16 EGO57563.1 - 3e-17 62.4 0.0 4.7e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Phosphodiest PF01663.17 EGO57567.1 - 2.6e-14 53.3 0.5 5.5e-14 52.2 0.1 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EGO57567.1 - 1.6e-05 24.4 0.2 3.6e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EGO57567.1 - 2.9e-05 23.4 0.0 0.00072 18.8 0.0 2.4 2 0 0 2 2 2 1 Sulfatase DUF229 PF02995.12 EGO57567.1 - 0.35 9.2 0.0 0.51 8.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) 2TM PF13239.1 EGO57567.1 - 4.3 7.4 8.5 7.6 6.6 0.8 3.7 2 1 1 3 3 3 0 2TM domain DUF4271 PF14093.1 EGO57568.1 - 0.071 12.7 0.0 0.096 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) PUF PF00806.14 EGO57569.1 - 1.7e-48 159.4 1.8 4e-07 29.1 0.0 8.4 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat Phage_mat-A PF03863.8 EGO57569.1 - 0.014 14.4 0.1 0.03 13.3 0.1 1.4 1 0 0 1 1 1 0 Phage maturation protein DUF684 PF05075.9 EGO57569.1 - 0.045 12.3 1.0 0.083 11.4 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF684) Meth_synt_2 PF01717.13 EGO57570.1 - 1e-142 474.8 0.0 2.5e-137 457.2 0.0 2.5 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EGO57570.1 - 1.4e-125 418.7 0.0 4.9e-114 380.7 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.4 EGO57570.1 - 6.9 6.2 8.0 0.49 9.9 0.2 2.9 3 0 0 3 3 3 0 Short C-terminal domain Acyl-CoA_dh_M PF02770.14 EGO57571.1 - 0.065 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain EF-hand_4 PF12763.2 EGO57572.1 - 5.5e-26 90.3 0.0 5.6e-14 51.7 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 EGO57572.1 - 1.8e-12 47.1 187.5 8.6e-07 28.9 21.8 7.6 4 2 2 7 7 7 4 Domain of unknown function (DUF1720) EF-hand_1 PF00036.27 EGO57572.1 - 0.00013 21.0 0.0 0.35 10.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EGO57572.1 - 0.00039 20.5 0.3 0.97 9.6 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGO57572.1 - 0.0051 16.5 0.3 1.4 8.9 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain PIN_4 PF13638.1 EGO57573.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.5 2 0 0 2 2 2 0 PIN domain Fork_head PF00250.13 EGO57575.1 - 6.2e-34 115.9 0.2 1.6e-33 114.6 0.2 1.6 1 0 0 1 1 1 1 Fork head domain DUF1649 PF07855.7 EGO57576.1 - 6.4e-64 214.5 0.0 7.9e-64 214.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) DUF2763 PF10961.3 EGO57576.1 - 0.12 12.7 14.1 0.21 11.9 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) GRP PF07172.6 EGO57576.1 - 2.9 8.4 21.4 2.2 8.8 1.7 2.3 2 0 0 2 2 2 0 Glycine rich protein family Peroxin-3 PF04882.7 EGO57577.1 - 3.8e-150 500.3 0.0 4.4e-150 500.1 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 DGCR6 PF07324.6 EGO57577.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein Sybindin PF04099.7 EGO57578.1 - 1.4e-22 79.9 0.0 2e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EGO57578.1 - 0.042 13.6 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Pkinase PF00069.20 EGO57579.1 - 1.2e-62 211.4 0.0 1.8e-62 210.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57579.1 - 1.2e-34 119.6 0.0 1.6e-33 115.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO57579.1 - 8e-09 34.8 0.0 3.6e-08 32.7 0.0 1.9 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EGO57579.1 - 0.00072 19.3 0.0 0.0018 18.0 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family AMPKBI PF04739.10 EGO57579.1 - 0.17 11.7 2.6 12 5.7 0.0 2.6 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interation domain Pkinase PF00069.20 EGO57581.1 - 4e-64 216.2 0.0 5.7e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57581.1 - 2.2e-27 95.7 0.0 3e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGO57581.1 - 0.0093 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGO57581.1 - 0.018 13.9 0.0 0.035 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 EGO57581.1 - 0.08 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family MaoC_dehydratas PF01575.14 EGO57582.1 - 0.044 13.1 0.1 0.094 12.1 0.1 1.5 1 0 0 1 1 1 0 MaoC like domain Menin PF05053.8 EGO57583.1 - 0.018 13.2 3.5 0.029 12.5 2.4 1.2 1 0 0 1 1 1 0 Menin Pkinase PF00069.20 EGO57584.1 - 1.6e-70 237.2 0.0 2.9e-70 236.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57584.1 - 2.8e-51 174.0 0.0 4.7e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EGO57584.1 - 2e-29 101.6 0.1 7.3e-29 99.7 0.0 1.9 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 EGO57584.1 - 2e-17 62.7 0.2 1.2e-16 60.2 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGO57584.1 - 2.3e-15 56.4 0.0 4.2e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EGO57584.1 - 6.1e-14 52.2 0.0 1.2e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 EGO57584.1 - 9.1e-08 31.4 0.0 4.8e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.11 EGO57584.1 - 0.0079 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Kdo PF06293.9 EGO57584.1 - 0.027 13.5 0.0 0.053 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pput2613-deam PF14427.1 EGO57584.1 - 0.14 11.8 0.1 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Pput_2613-like deaminase Ste50p-SAM PF09235.5 EGO57584.1 - 0.2 11.7 0.4 0.56 10.2 0.3 1.8 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Ureide_permease PF07168.6 EGO57584.1 - 0.24 10.0 0.0 0.37 9.4 0.0 1.2 1 0 0 1 1 1 0 Ureide permease Pep3_Vps18 PF05131.9 EGO57586.1 - 1.2e-49 167.4 0.0 4.1e-49 165.7 0.0 1.9 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EGO57586.1 - 3.5e-12 46.1 2.2 5e-09 35.8 0.1 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EGO57586.1 - 0.00038 20.2 0.9 0.00038 20.2 0.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EGO57586.1 - 0.0017 18.0 1.1 0.0017 18.0 0.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain DUF2175 PF09943.4 EGO57586.1 - 0.009 16.0 0.4 0.065 13.2 0.1 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) Vps39_2 PF10367.4 EGO57586.1 - 0.017 15.2 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 TPR_21 PF09976.4 EGO57586.1 - 0.032 14.1 0.2 0.089 12.7 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 EGO57586.1 - 2 8.1 5.5 0.28 10.8 0.5 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO57586.1 - 6.8 6.8 7.5 0.22 11.5 0.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pertussis_S1 PF02917.9 EGO57588.1 - 1.3 8.5 7.0 2 7.9 4.8 1.2 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 zf-C2H2 PF00096.21 EGO57589.1 - 0.0032 17.7 2.6 0.0032 17.7 1.8 5.0 6 0 0 6 6 6 2 Zinc finger, C2H2 type Shugoshin_N PF07558.6 EGO57589.1 - 0.67 9.7 3.4 1.2 8.8 2.4 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region zf-H2C2_2 PF13465.1 EGO57589.1 - 1.4 9.3 19.2 3.2 8.2 2.1 4.1 4 0 0 4 4 4 0 Zinc-finger double domain Lyase_1 PF00206.15 EGO57590.1 - 6.5e-26 91.2 0.2 9.6e-26 90.6 0.1 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EGO57590.1 - 2.9e-15 56.0 0.0 9.6e-15 54.3 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Luciferase_N PF05295.6 EGO57590.1 - 0.087 12.6 0.0 1.7 8.4 0.0 2.7 2 0 0 2 2 2 0 Luciferase/LBP N-terminal domain Polysacc_deac_1 PF01522.16 EGO57592.1 - 4.4e-30 103.8 0.0 7.2e-30 103.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EGO57592.1 - 6.8e-06 25.9 15.8 6.8e-06 25.9 10.9 3.3 3 0 0 3 3 3 1 Chitin recognition protein Aminotran_1_2 PF00155.16 EGO57593.1 - 2.2e-80 270.3 0.0 2.8e-80 269.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGO57593.1 - 7.5e-05 21.6 0.0 0.00025 19.8 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGO57593.1 - 0.00012 20.5 0.0 0.00019 19.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SNF2_N PF00176.18 EGO57594.1 - 9e-35 119.9 0.0 2.8e-30 105.1 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO57594.1 - 2.1e-15 56.3 0.0 4.8e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO57594.1 - 3.1e-05 23.8 0.0 0.00015 21.6 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3390 PF11870.3 EGO57594.1 - 0.0037 17.1 0.4 0.13 12.1 0.7 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3390) zf-dskA_traR PF01258.12 EGO57594.1 - 0.19 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger S1-like PF14444.1 EGO57594.1 - 0.21 11.3 0.0 2.4 7.9 0.0 2.7 3 0 0 3 3 3 0 S1-like GSH_synth_ATP PF03917.12 EGO57595.1 - 2e-112 375.5 0.0 2.4e-112 375.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EGO57595.1 - 1.9e-30 105.0 0.0 3.7e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Sec1 PF00995.18 EGO57596.1 - 2.4e-154 515.1 0.0 2.7e-154 514.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family B12-binding PF02310.14 EGO57596.1 - 0.027 14.3 0.1 0.074 12.9 0.1 1.7 1 0 0 1 1 1 0 B12 binding domain DUF2404 PF10296.4 EGO57597.1 - 2.4e-08 34.0 0.0 4.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) MBOAT PF03062.14 EGO57598.1 - 2.4e-51 174.7 4.8 2.4e-51 174.7 3.3 2.0 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Abi PF02517.11 EGO57600.1 - 2.5e-11 43.5 14.7 1.6e-10 40.9 10.2 2.3 1 1 0 1 1 1 1 CAAX protease self-immunity UAA PF08449.6 EGO57601.1 - 2.9e-13 49.4 21.3 3.5e-13 49.1 14.8 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EGO57601.1 - 2.2e-09 37.1 7.2 2.2e-09 37.1 5.0 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EGO57601.1 - 0.00069 19.6 29.4 0.0081 16.2 5.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family PUF PF00806.14 EGO57602.1 - 2.2e-27 92.9 0.0 3.2e-05 23.1 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EGO57602.1 - 1.9e-13 49.8 0.0 4.5e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO57602.1 - 9.1e-07 28.6 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO57602.1 - 1.6e-06 27.9 0.0 5.5e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2811 PF10929.3 EGO57602.1 - 0.011 15.6 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2811) Pex14_N PF04695.8 EGO57602.1 - 0.64 10.0 17.9 0.32 11.0 9.8 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 EGO57602.1 - 1.1 8.8 14.1 0.093 12.4 5.1 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF1682 PF07946.9 EGO57603.1 - 1.6e-110 368.9 1.0 1.9e-110 368.6 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) VIT1 PF01988.14 EGO57603.1 - 0.21 11.0 0.1 0.21 11.0 0.1 2.3 2 1 0 2 2 2 0 VIT family DUF77 PF01910.12 EGO57604.1 - 6.4e-33 112.2 2.1 7.4e-33 112.0 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Polysacc_deac_1 PF01522.16 EGO57604.1 - 0.028 14.0 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide deacetylase Pkinase PF00069.20 EGO57605.1 - 4.5e-38 130.8 0.0 6.7e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57605.1 - 6.8e-27 94.1 0.0 9.8e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO57605.1 - 0.0021 17.1 0.0 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO57605.1 - 0.0069 16.1 0.0 0.79 9.3 0.0 2.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO57605.1 - 0.012 14.7 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ecl1 PF12855.2 EGO57606.1 - 6.4e-12 44.5 2.7 1.3e-11 43.5 1.9 1.5 1 0 0 1 1 1 1 Life-span regulatory factor DUF581 PF04570.9 EGO57606.1 - 0.048 12.9 4.2 0.1 11.9 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF581) zf-MYND PF01753.13 EGO57606.1 - 0.18 11.7 1.2 0.34 10.8 0.8 1.4 1 0 0 1 1 1 0 MYND finger WD40 PF00400.27 EGO57610.1 - 2.7e-69 226.7 13.2 2.5e-11 43.0 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EGO57610.1 - 3e-24 85.0 7.3 4.7e-24 84.3 5.1 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 EGO57610.1 - 0.00062 18.0 0.6 0.52 8.3 0.0 3.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGO57610.1 - 0.0043 15.8 0.1 0.64 8.7 0.0 3.2 1 1 2 4 4 4 1 Nup133 N terminal like Nbas_N PF15492.1 EGO57610.1 - 0.014 14.4 1.0 13 4.8 0.0 3.4 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Myosin_tail_1 PF01576.14 EGO57610.1 - 0.017 12.8 3.1 0.023 12.4 2.1 1.0 1 0 0 1 1 1 0 Myosin tail Cytochrom_D1 PF02239.11 EGO57610.1 - 0.066 11.5 0.2 0.48 8.6 0.1 2.2 1 1 2 3 3 3 0 Cytochrome D1 heme domain PD40 PF07676.7 EGO57610.1 - 0.085 12.5 2.4 18 5.1 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EGO57610.1 - 0.57 9.5 3.2 14 5.1 0.0 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature FA_hydroxylase PF04116.8 EGO57612.1 - 4.6e-14 52.7 19.5 4.6e-14 52.7 13.5 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2015 PF09435.5 EGO57613.1 - 2.1e-48 163.3 0.0 2.4e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) DNA_ligase_OB_2 PF14743.1 EGO57613.1 - 0.048 13.3 0.1 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 DNA ligase OB-like domain Ribosomal_L28e PF01778.12 EGO57614.1 - 1.1e-38 132.2 0.1 1.4e-38 131.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Lys-AminoMut_A PF09043.6 EGO57614.1 - 0.027 12.5 0.2 0.034 12.2 0.1 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase alpha subunit HIGH_NTase1 PF05636.6 EGO57614.1 - 0.061 12.3 0.5 0.075 12.0 0.3 1.1 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase Ldh_1_N PF00056.18 EGO57615.1 - 4.1e-44 149.8 0.1 5.9e-44 149.3 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EGO57615.1 - 1e-43 149.0 0.0 1.4e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EGO57615.1 - 0.014 14.0 0.0 0.034 12.8 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family TRAPP PF04051.11 EGO57616.1 - 4.7e-48 162.5 0.0 5.6e-48 162.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PorB PF11565.3 EGO57616.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha helical Porin B PINIT PF14324.1 EGO57617.1 - 2.7e-34 118.3 0.1 4.8e-34 117.4 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EGO57617.1 - 7.1e-22 76.6 4.4 1.2e-21 75.8 3.0 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 EGO57617.1 - 7.1e-09 34.9 0.8 2.4e-07 30.1 0.0 3.1 2 1 1 3 3 3 1 SAP domain zf-Nse PF11789.3 EGO57617.1 - 2.2e-05 23.8 0.5 4.6e-05 22.8 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EGO57617.1 - 0.0012 18.7 5.5 0.002 17.9 3.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Sec23_Sec24 PF04810.10 EGO57617.1 - 0.019 14.5 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-RING_5 PF14634.1 EGO57617.1 - 0.054 13.2 2.8 0.093 12.4 1.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 EGO57617.1 - 0.078 12.8 4.1 0.13 12.0 2.8 1.4 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.24 EGO57617.1 - 0.3 10.8 2.2 0.65 9.7 1.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.1 EGO57617.1 - 0.62 9.7 2.7 1.2 8.9 1.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO57617.1 - 1.3 9.0 4.3 2.5 8.2 3.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGO57617.1 - 3 7.6 6.6 0.19 11.4 0.3 2.1 2 0 0 2 2 2 0 RING-type zinc-finger DUF2423 PF10338.4 EGO57618.1 - 8.1e-19 67.3 2.6 8.1e-19 67.3 1.8 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Saccharop_dh_N PF04455.7 EGO57618.1 - 0.034 14.2 0.2 0.051 13.6 0.1 1.4 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region Sulfatase PF00884.18 EGO57619.1 - 0.00016 20.9 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EGO57619.1 - 0.0035 16.7 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Cnd3 PF12719.2 EGO57620.1 - 1.4e-97 326.2 1.5 5.5e-97 324.3 0.1 2.5 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EGO57620.1 - 1.5e-11 44.4 7.0 1.5e-05 25.1 0.6 5.2 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.17 EGO57620.1 - 4.8e-06 26.2 9.6 0.19 11.8 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat DUF1546 PF07571.8 EGO57620.1 - 0.052 13.6 0.5 0.97 9.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 EGO57620.1 - 1.4 9.4 18.4 0.38 11.3 0.6 6.2 4 1 3 7 7 7 0 HEAT-like repeat RRM_1 PF00076.17 EGO57621.1 - 7.6e-60 198.4 0.6 1.6e-17 62.9 0.0 6.2 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO57621.1 - 2.7e-45 152.2 0.0 6.3e-13 48.5 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO57621.1 - 1.2e-19 69.9 0.0 2.5e-07 30.4 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zip PF02535.17 EGO57621.1 - 0.39 9.6 4.1 2 7.3 0.7 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter CDC45 PF02724.9 EGO57621.1 - 7.6 4.4 31.6 0.0051 14.9 10.2 2.4 2 0 0 2 2 2 0 CDC45-like protein Mg_trans_NIPA PF05653.9 EGO57622.1 - 2.1e-61 207.5 9.4 2e-58 197.7 3.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EGO57622.1 - 2e-05 24.7 0.8 2e-05 24.7 0.6 3.7 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EGO57622.1 - 0.0064 16.5 2.4 0.0064 16.5 1.7 3.9 3 1 1 4 4 4 1 EamA-like transporter family LRR19-TM PF15176.1 EGO57622.1 - 0.0093 15.6 0.4 0.046 13.4 0.0 2.3 2 0 0 2 2 2 1 Leucine-rich repeat family 19 TM domain DUF914 PF06027.7 EGO57622.1 - 0.036 12.9 2.2 3.3 6.4 0.4 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) DUF4131 PF13567.1 EGO57622.1 - 0.82 9.0 8.5 1.3 8.3 0.1 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Bac_thur_toxin PF01338.13 EGO57624.1 - 0.1 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacillus thuringiensis toxin Tyr-DNA_phospho PF06087.7 EGO57626.1 - 5.7e-76 255.9 0.0 7.5e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EGO57626.1 - 0.00011 21.9 0.0 0.012 15.3 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PNRC PF15365.1 EGO57627.1 - 0.00034 20.5 4.8 0.00034 20.5 3.3 5.2 3 1 2 5 5 5 2 Proline-rich nuclear receptor coactivator zf-rbx1 PF12678.2 EGO57628.1 - 4.1e-35 119.7 13.5 5.2e-35 119.3 9.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGO57628.1 - 4.7e-17 61.6 9.9 6.7e-17 61.1 6.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EGO57628.1 - 3.6e-07 29.8 11.9 3.3e-06 26.8 8.3 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGO57628.1 - 0.0013 18.3 11.3 0.022 14.4 7.9 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO57628.1 - 0.0051 16.4 10.0 0.54 9.9 7.1 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO57628.1 - 0.043 13.8 12.6 0.047 13.7 5.4 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EGO57628.1 - 0.7 9.9 9.2 3.4 7.7 6.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.1 EGO57628.1 - 0.73 9.6 12.3 7.3 6.3 8.5 2.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGO57628.1 - 1.7 8.4 7.0 38 4.1 4.9 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 EGO57628.1 - 2.2 8.4 10.7 1.3e+02 2.8 7.4 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain CorA PF01544.13 EGO57629.1 - 2.4e-42 144.9 0.1 3.4e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-Tim10_DDP PF02953.10 EGO57630.1 - 4.2e-21 73.9 1.2 5.1e-21 73.7 0.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_L23eN PF03939.8 EGO57631.1 - 2.2e-20 72.4 10.3 2.2e-20 72.4 7.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EGO57631.1 - 4.5e-16 58.5 1.3 1.1e-15 57.2 0.9 1.7 1 0 0 1 1 1 1 Ribosomal protein L23 DUF3321 PF11968.3 EGO57632.1 - 1.6e-97 325.4 0.0 2.1e-97 325.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EGO57632.1 - 0.00018 21.2 0.0 0.00053 19.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain HAD_2 PF13419.1 EGO57635.1 - 2.3e-24 86.5 0.0 2.9e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO57635.1 - 0.00084 19.0 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 EGO57635.1 - 0.13 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase Pkinase PF00069.20 EGO57638.1 - 4.9e-60 202.8 0.0 9e-60 202.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57638.1 - 9e-33 113.4 0.0 1.5e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO57638.1 - 1.3e-13 50.5 0.0 1.9e-11 43.4 0.0 2.4 2 1 0 2 2 2 2 Kinase-like APH PF01636.18 EGO57638.1 - 0.0082 15.8 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO57638.1 - 0.032 13.2 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aa_trans PF01490.13 EGO57639.1 - 7.1e-58 196.0 32.4 8.6e-58 195.7 22.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Iso_dh PF00180.15 EGO57640.1 - 9.1e-135 449.0 0.0 1e-134 448.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4451 PF14616.1 EGO57643.1 - 5.9e-08 32.5 1.0 2.3e-07 30.5 0.8 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4451) Actin PF00022.14 EGO57646.1 - 1.2e-30 106.1 0.0 8.8e-20 70.4 0.0 2.6 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EGO57646.1 - 0.05 12.2 0.0 0.83 8.1 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein CorA PF01544.13 EGO57647.1 - 0.016 14.2 0.1 0.016 14.2 0.1 2.5 2 1 0 3 3 3 0 CorA-like Mg2+ transporter protein DUF2029 PF09594.5 EGO57647.1 - 0.071 12.6 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) DUF4381 PF14316.1 EGO57647.1 - 0.2 11.7 1.4 4.8 7.2 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) Pkinase PF00069.20 EGO57648.1 - 3.6e-72 242.6 0.9 9.9e-72 241.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57648.1 - 2.3e-37 128.4 1.1 2.8e-37 128.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO57648.1 - 1.8e-08 33.7 0.0 3.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PAT1 PF09770.4 EGO57648.1 - 0.23 9.6 46.8 0.29 9.3 32.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EGO57648.1 - 1.8 8.3 34.8 3 7.6 24.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF737 PF05300.6 EGO57648.1 - 3.1 7.7 15.2 0.33 10.8 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Lectin_leg-like PF03388.8 EGO57649.1 - 6.6e-65 218.4 0.0 9.1e-65 218.0 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EGO57649.1 - 0.0076 15.6 0.0 2.2 7.5 0.0 2.3 2 0 0 2 2 2 2 Legume lectin domain DUF2040 PF09745.4 EGO57650.1 - 3.6e-39 133.4 28.5 3.6e-39 133.4 19.7 4.3 2 2 2 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) zf-Tim10_DDP PF02953.10 EGO57651.1 - 2.9e-20 71.3 0.8 3.6e-20 71.0 0.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.3 EGO57651.1 - 0.0023 17.7 0.1 0.0028 17.4 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3398) DUF842 PF05811.8 EGO57651.1 - 0.019 14.4 0.8 0.026 14.0 0.5 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) TIL PF01826.12 EGO57651.1 - 0.065 13.3 1.5 0.097 12.8 1.0 1.3 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain PI-PLC-X PF00388.14 EGO57652.1 - 9.2e-69 229.4 0.0 1.4e-68 228.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EGO57652.1 - 2.1e-38 130.9 0.0 4.4e-38 129.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EGO57652.1 - 0.041 13.7 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 C2 domain DEAD PF00270.24 EGO57653.1 - 8e-33 113.3 0.0 1.4e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO57653.1 - 2e-16 59.5 0.0 4.9e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO57653.1 - 0.00018 21.3 0.0 0.00051 19.9 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EGO57653.1 - 0.1 11.8 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain DUF1762 PF08574.5 EGO57655.1 - 2.8e-06 27.6 12.8 2.8e-06 27.6 8.9 2.9 3 1 1 4 4 4 1 Protein of unknown function (DUF1762) Pkinase PF00069.20 EGO57656.1 - 1.3e-57 194.9 0.0 1.9e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57656.1 - 1.3e-20 73.6 0.0 2e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO57656.1 - 1.5e-07 30.7 0.0 2.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGO57656.1 - 1.6e-05 24.1 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO57656.1 - 3.2e-05 23.7 0.3 0.001 18.8 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 EGO57656.1 - 0.005 16.2 0.1 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 RIO1 family PAS_9 PF13426.1 EGO57656.1 - 0.12 12.7 0.0 0.78 10.1 0.0 2.4 2 0 0 2 2 2 0 PAS domain F-box-like PF12937.2 EGO57657.1 - 7.2e-10 38.4 0.4 3.3e-09 36.3 0.1 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EGO57657.1 - 4e-08 32.7 0.1 1.3e-07 31.0 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.1 EGO57657.1 - 1.6e-07 30.6 10.1 0.0055 16.6 0.0 7.6 10 0 0 10 10 10 2 Leucine Rich repeat LRR_4 PF12799.2 EGO57657.1 - 1.7e-07 30.7 4.3 0.89 9.2 0.0 6.5 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO57657.1 - 2.8e-06 26.9 4.1 0.011 15.5 0.1 5.3 5 1 1 6 6 6 1 Leucine rich repeat LRR_1 PF00560.28 EGO57657.1 - 4.6e-05 22.8 11.9 0.1 12.7 0.0 6.9 8 1 0 8 8 8 1 Leucine Rich Repeat PRANC PF09372.5 EGO57657.1 - 0.02 14.8 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 PRANC domain LRR_7 PF13504.1 EGO57657.1 - 4.2 8.0 16.9 2.7 8.5 0.1 6.8 8 0 0 8 8 8 0 Leucine rich repeat KH_1 PF00013.24 EGO57658.1 - 7.2e-39 131.2 11.3 3.5e-14 52.2 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EGO57658.1 - 5.7e-30 102.4 13.3 1.8e-11 43.3 1.0 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EGO57658.1 - 1.4e-10 40.5 8.1 0.0051 16.3 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EGO57658.1 - 1.5e-09 37.3 3.1 0.03 13.9 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EGO57658.1 - 0.001 18.8 5.0 1.6 8.6 0.2 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EGO57658.1 - 0.0082 15.6 0.3 1.2 8.6 0.0 3.0 3 0 0 3 3 3 1 dUTPase UAA PF08449.6 EGO57659.1 - 2.3e-73 246.7 6.4 5e-73 245.6 4.4 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGO57659.1 - 1.9e-10 40.8 23.4 1.6e-06 28.1 3.3 3.6 3 1 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.10 EGO57659.1 - 2.4e-06 26.8 1.9 0.018 14.1 0.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EGO57659.1 - 2.7e-05 24.3 15.3 0.00066 19.8 3.2 2.7 2 0 0 2 2 2 2 Multidrug resistance efflux transporter TPT PF03151.11 EGO57659.1 - 5.1e-05 22.9 4.4 5.1e-05 22.9 3.0 2.8 3 0 0 3 3 3 1 Triose-phosphate Transporter family SPW PF03779.9 EGO57659.1 - 0.15 11.4 2.9 0.5 9.7 0.4 2.8 2 0 0 2 2 2 0 SPW repeat DUF2986 PF11661.3 EGO57659.1 - 5 7.5 9.4 0.47 10.8 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2986) DSPc PF00782.15 EGO57660.1 - 1.6e-25 89.2 0.0 1.9e-23 82.5 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGO57660.1 - 0.00089 18.6 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EGO57660.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase PTS_2-RNA PF01885.11 EGO57664.1 - 5.7e-67 224.6 0.0 7.1e-67 224.3 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 EGO57664.1 - 0.059 13.1 0.0 0.69 9.7 0.0 2.1 2 0 0 2 2 2 0 La domain DUF2690 PF10901.3 EGO57665.1 - 0.0066 16.4 0.2 0.042 13.8 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2690) His_Phos_1 PF00300.17 EGO57666.1 - 1.6e-23 83.5 0.0 2.4e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RabGAP-TBC PF00566.13 EGO57668.1 - 2.6e-27 95.6 0.2 2.6e-27 95.6 0.2 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PAT1 PF09770.4 EGO57668.1 - 2.2 6.4 22.6 3.1 5.9 15.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PX PF00787.19 EGO57670.1 - 2.1e-19 69.4 0.0 8.2e-19 67.4 0.0 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EGO57670.1 - 1.2e-14 54.2 12.8 3.5e-09 36.2 0.7 2.1 2 0 0 2 2 2 2 Vps5 C terminal like mRNA_cap_enzyme PF01331.14 EGO57671.1 - 7e-49 166.1 0.1 1e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EGO57671.1 - 2.1e-18 66.5 0.0 4.3e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EGO57671.1 - 5e-10 39.0 0.1 1.4e-08 34.4 0.0 2.6 2 1 0 2 2 2 1 ATP dependent DNA ligase domain UPRTase PF14681.1 EGO57672.1 - 1.6e-73 246.3 0.0 1.9e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EGO57672.1 - 1.1e-05 25.1 0.1 3.2e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.12 EGO57672.1 - 0.0054 15.8 0.2 0.14 11.2 0.0 2.1 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI CRCB PF02537.10 EGO57673.1 - 1.8e-32 111.6 14.6 8.1e-20 70.8 5.4 3.6 3 1 0 3 3 3 3 CrcB-like protein DNA_ligase_A_M PF01068.16 EGO57675.1 - 7.7e-43 146.2 0.0 1.2e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGO57675.1 - 4.9e-37 127.4 0.0 7.7e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGO57675.1 - 1.2e-16 60.9 0.8 4.3e-16 59.1 0.0 2.4 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EGO57675.1 - 7.1e-08 32.4 0.0 3.6e-05 23.8 0.0 3.0 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain UPF0560 PF10577.4 EGO57675.1 - 0.012 13.9 0.1 0.018 13.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 mRNA_cap_enzyme PF01331.14 EGO57675.1 - 0.068 12.8 0.0 0.68 9.5 0.0 2.5 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain DNA_ligase_IV PF11411.3 EGO57675.1 - 0.099 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 DNA ligase IV DUF4449 PF14613.1 EGO57676.1 - 1.2e-68 230.1 0.3 1.2e-68 230.1 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) DUF1841 PF08897.6 EGO57676.1 - 0.039 13.7 0.7 0.11 12.3 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) TipAS PF07739.8 EGO57676.1 - 0.52 10.6 6.3 0.64 10.3 1.4 3.2 4 0 0 4 4 4 0 TipAS antibiotic-recognition domain DOT1 PF08123.8 EGO57677.1 - 2.3e-79 265.5 0.0 3.6e-79 264.8 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 EGO57677.1 - 3.1e-05 23.5 0.0 8.7e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO57677.1 - 8.8e-05 22.5 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO57677.1 - 0.00029 21.4 0.1 0.0009 19.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ATG16 PF08614.6 EGO57678.1 - 4.7e-60 202.7 16.7 6.2e-60 202.3 11.6 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.1 EGO57678.1 - 5.9e-05 22.5 9.2 5.9e-05 22.5 6.4 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) CCDC144C PF14915.1 EGO57678.1 - 0.0013 17.7 9.9 0.051 12.5 4.7 2.2 2 0 0 2 2 2 2 CCDC144C protein coiled-coil region GAS PF13851.1 EGO57678.1 - 0.0041 16.3 10.9 0.01 15.0 5.3 2.1 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 EGO57678.1 - 0.0048 15.4 9.0 0.015 13.7 6.2 1.6 1 1 0 1 1 1 1 AAA domain Pro-rich_19 PF15455.1 EGO57678.1 - 0.019 14.0 0.8 0.023 13.7 0.6 1.2 1 0 0 1 1 1 0 Proline-rich 19 DUF4109 PF13397.1 EGO57678.1 - 0.059 13.7 1.8 0.067 13.5 0.4 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4109) IncA PF04156.9 EGO57678.1 - 0.092 12.3 10.7 0.074 12.6 3.8 2.2 2 0 0 2 2 2 0 IncA protein Herpes_UL6 PF01763.11 EGO57678.1 - 0.24 9.5 9.0 0.21 9.7 0.1 2.2 1 1 2 3 3 3 0 Herpesvirus UL6 like Troponin PF00992.15 EGO57678.1 - 0.26 11.3 0.1 0.26 11.3 0.1 3.0 2 1 1 3 3 3 0 Troponin DUF4140 PF13600.1 EGO57678.1 - 0.41 11.1 13.8 4.1 7.8 0.1 3.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4600 PF15372.1 EGO57678.1 - 0.45 10.7 11.3 1.5 9.0 5.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) APG6 PF04111.7 EGO57678.1 - 0.59 9.1 11.7 2.1 7.3 5.7 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 EGO57678.1 - 0.75 9.6 14.3 6.5 6.6 0.0 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding CENP-H PF05837.7 EGO57678.1 - 0.76 9.9 13.5 0.28 11.3 1.3 3.1 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Atg14 PF10186.4 EGO57678.1 - 0.85 8.4 14.8 7.7 5.3 10.2 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4200 PF13863.1 EGO57678.1 - 0.94 9.4 13.6 15 5.5 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Macoilin PF09726.4 EGO57678.1 - 0.97 7.6 13.1 1.2 7.2 9.1 1.1 1 0 0 1 1 1 0 Transmembrane protein SecD-TM1 PF13721.1 EGO57678.1 - 1.1 9.5 3.9 2.6 8.3 0.8 2.5 1 1 1 2 2 2 0 SecD export protein N-terminal TM region YkyA PF10368.4 EGO57678.1 - 1.1 8.5 10.2 1.1 8.5 4.6 2.0 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Nup54 PF13874.1 EGO57678.1 - 2.3 7.9 14.9 1.4 8.5 2.6 2.9 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 DUF972 PF06156.8 EGO57678.1 - 2.5 8.4 13.8 12 6.2 2.3 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF972) Tropomyosin_1 PF12718.2 EGO57678.1 - 2.9 7.7 20.4 8.5 6.2 10.6 2.7 2 1 1 3 3 3 0 Tropomyosin like Baculo_PP31 PF05311.6 EGO57678.1 - 3.2 6.9 6.2 2.8 7.1 1.9 2.0 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) TBPIP PF07106.8 EGO57678.1 - 3.3 7.2 11.9 3.6 7.1 5.4 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TSC22 PF01166.13 EGO57678.1 - 3.5 7.6 9.2 6.5 6.7 1.4 3.1 2 1 0 3 3 3 0 TSC-22/dip/bun family Ly49 PF08391.5 EGO57678.1 - 5 7.2 7.0 13 5.9 2.1 2.6 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region DUF4398 PF14346.1 EGO57678.1 - 6.4 6.8 11.7 9.9 6.2 0.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4398) Spc7 PF08317.6 EGO57678.1 - 7.2 5.1 13.3 3.4 6.2 7.0 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 EGO57678.1 - 9.3 6.0 13.5 11 5.8 7.0 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein SlyX PF04102.7 EGO57678.1 - 9.6 6.6 11.3 43 4.5 2.1 3.4 2 1 1 3 3 3 0 SlyX Vps16_N PF04841.8 EGO57679.1 - 4.8e-96 321.7 0.0 7.3e-96 321.1 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EGO57679.1 - 2.2e-65 220.7 0.0 7.7e-65 218.9 0.0 1.8 1 1 0 1 1 1 1 Vps16, C-terminal region FHA PF00498.21 EGO57680.1 - 1.3e-14 54.0 1.3 2.7e-14 53.0 0.0 2.3 3 0 0 3 3 1 1 FHA domain zf-RING_2 PF13639.1 EGO57680.1 - 3.1e-07 30.1 8.8 5.2e-07 29.3 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGO57680.1 - 8.8e-05 22.5 3.2 0.00017 21.6 2.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-HC5HC2H PF13771.1 EGO57680.1 - 0.00083 19.4 0.7 0.0017 18.4 0.5 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-C3HC4 PF00097.20 EGO57680.1 - 0.0015 18.1 8.8 0.0025 17.4 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGO57680.1 - 0.0056 16.4 1.7 0.01 15.6 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EGO57680.1 - 0.013 15.2 6.6 0.021 14.5 4.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 EGO57680.1 - 0.015 14.9 4.4 0.027 14.1 3.1 1.4 1 0 0 1 1 1 0 PHD-finger Cys_rich_CPXG PF14255.1 EGO57680.1 - 0.04 13.7 0.5 0.37 10.6 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-HC5HC2H_2 PF13832.1 EGO57680.1 - 0.046 13.7 1.7 0.096 12.6 1.2 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-C3HC4_2 PF13923.1 EGO57680.1 - 0.13 12.2 10.3 0.23 11.4 7.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EGO57680.1 - 0.59 10.1 5.6 1.1 9.3 3.9 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 EGO57680.1 - 1 9.3 6.4 2.3 8.1 4.4 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Peptidase_M16_C PF05193.16 EGO57681.1 - 1.3e-61 207.5 0.0 3.1e-61 206.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGO57681.1 - 1.7e-45 154.4 0.0 3.5e-45 153.4 0.0 1.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Herpes_env PF01673.13 EGO57682.1 - 0.32 9.5 1.6 0.54 8.7 1.1 1.3 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein FimP PF09766.4 EGO57682.1 - 9.9 5.1 20.6 16 4.3 14.3 1.3 1 0 0 1 1 1 0 Fms-interacting protein S1 PF00575.18 EGO57683.1 - 6.6e-96 314.4 50.6 4.6e-19 68.2 0.3 13.5 13 0 0 13 13 13 11 S1 RNA binding domain TPR_14 PF13428.1 EGO57683.1 - 1.5e-05 25.1 3.8 0.68 10.7 0.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO57683.1 - 2.2e-05 25.0 0.5 0.09 13.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat S1_2 PF13509.1 EGO57683.1 - 4.7e-05 23.2 0.2 6.4 6.7 0.0 5.2 4 0 0 4 4 4 1 S1 domain TPR_6 PF13174.1 EGO57683.1 - 0.00024 21.3 2.3 4 8.0 0.0 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO57683.1 - 0.00027 21.2 0.5 2.1 8.7 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGO57683.1 - 0.011 15.3 0.1 0.18 11.4 0.0 2.6 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 EGO57683.1 - 0.24 11.4 1.3 1.1 9.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Suf PF05843.9 EGO57683.1 - 1.2 8.7 17.6 0.54 9.9 0.6 4.3 2 2 1 3 3 3 0 Suppressor of forked protein (Suf) EF-hand_4 PF12763.2 EGO57688.1 - 4e-05 23.2 0.0 8.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand MAP65_ASE1 PF03999.7 EGO57689.1 - 6.4e-76 256.2 5.0 6.4e-76 256.2 3.5 1.9 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Sipho_Gp157 PF05565.6 EGO57689.1 - 0.0013 18.3 5.7 0.027 14.0 0.1 2.7 2 0 0 2 2 2 2 Siphovirus Gp157 Spectrin PF00435.16 EGO57689.1 - 0.42 10.9 17.2 1.5 9.1 0.2 4.3 3 1 1 4 4 4 0 Spectrin repeat DUF948 PF06103.6 EGO57689.1 - 1 9.2 6.5 14 5.6 1.3 3.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) EAP30 PF04157.11 EGO57689.1 - 6.6 5.8 9.9 3.9 6.5 0.0 3.5 4 0 0 4 4 4 0 EAP30/Vps36 family GTP_EFTU PF00009.22 EGO57690.1 - 1.9e-55 187.2 0.0 3.1e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EGO57690.1 - 3.2e-16 58.9 0.0 8.8e-16 57.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGO57690.1 - 3.4e-09 36.6 0.0 9.4e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EGO57690.1 - 2e-08 33.9 0.0 4.7e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EGO57690.1 - 1.3e-06 27.9 0.1 0.00018 21.0 0.0 3.1 3 1 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EGO57690.1 - 0.0083 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Paf67 PF10255.4 EGO57691.1 - 1.3e-154 514.9 0.2 1.6e-154 514.6 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EGO57691.1 - 0.022 14.6 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Usp PF00582.21 EGO57693.1 - 5.6e-08 33.0 1.3 3e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Universal stress protein family ABA_GPCR PF12430.3 EGO57694.1 - 3.1e-52 176.5 0.4 3.1e-52 176.5 0.3 1.5 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EGO57694.1 - 7.5e-20 70.7 0.0 4.2e-19 68.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) Herpes_BLLF1 PF05109.8 EGO57695.1 - 1.4 6.7 21.9 1.9 6.3 15.2 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) SH3_1 PF00018.23 EGO57696.1 - 2.1e-05 23.8 0.0 4.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGO57696.1 - 0.0083 15.6 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PalH PF08733.5 EGO57697.1 - 7.3e-106 353.9 0.0 8.8e-106 353.6 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 TRAM_LAG1_CLN8 PF03798.11 EGO57698.1 - 6.7e-33 113.9 22.9 6.7e-33 113.9 15.8 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EGO57698.1 - 8.5e-25 86.0 0.0 8.5e-25 86.0 0.0 2.0 2 0 0 2 2 2 1 TRAM1-like protein ABC_tran PF00005.22 EGO57701.1 - 8.7e-32 110.2 0.0 1.7e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EGO57701.1 - 9.5e-27 94.0 7.5 9.5e-27 94.0 5.2 2.3 2 0 0 2 2 2 1 ABC transporter transmembrane region SbcCD_C PF13558.1 EGO57701.1 - 0.0089 15.9 0.2 0.11 12.4 0.1 2.7 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EGO57701.1 - 0.014 14.5 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGO57701.1 - 0.018 14.5 0.3 0.045 13.2 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EGO57701.1 - 0.018 15.0 0.0 0.79 9.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain AhpC-TSA_2 PF13911.1 EGO57705.1 - 1.2e-10 41.3 0.0 1.9e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EGO57705.1 - 0.004 16.8 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Zn_clus PF00172.13 EGO57706.1 - 2.6e-06 27.2 8.5 6.2e-06 26.0 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGO57706.1 - 0.00014 20.5 0.2 0.0015 17.1 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain AAA PF00004.24 EGO57707.1 - 1.6e-98 326.0 0.0 9.1e-48 161.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EGO57707.1 - 1.1e-19 70.1 0.9 3.1e-19 68.6 0.3 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EGO57707.1 - 6.8e-14 51.4 0.0 3.5e-06 26.2 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EGO57707.1 - 6.9e-14 52.1 0.0 1.8e-07 31.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EGO57707.1 - 8.5e-13 48.2 1.3 9.3e-07 28.6 0.1 4.0 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EGO57707.1 - 1.5e-12 47.5 0.0 1.6e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGO57707.1 - 3.6e-12 46.5 0.3 0.00068 19.7 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGO57707.1 - 8.6e-12 45.4 0.0 0.0003 20.8 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EGO57707.1 - 3.2e-11 44.0 0.0 0.00033 21.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 EGO57707.1 - 2e-09 36.6 0.1 0.00085 18.1 0.0 2.9 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EGO57707.1 - 3.7e-09 36.2 5.4 0.014 14.7 0.0 4.7 3 2 2 5 5 4 3 AAA domain IstB_IS21 PF01695.12 EGO57707.1 - 2.6e-08 33.4 0.2 0.0053 16.1 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EGO57707.1 - 2.7e-08 33.7 0.0 0.0014 18.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGO57707.1 - 3.6e-08 33.0 1.8 0.0083 15.8 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain Mg_chelatase PF01078.16 EGO57707.1 - 1.7e-07 30.6 0.2 0.0057 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EGO57707.1 - 1.7e-07 30.5 0.1 0.011 14.8 0.0 2.7 3 0 0 3 3 3 2 Zeta toxin CDC48_2 PF02933.12 EGO57707.1 - 2.7e-07 30.1 0.0 6.7e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RNA_helicase PF00910.17 EGO57707.1 - 4.6e-07 29.9 0.0 0.026 14.6 0.0 2.9 3 0 0 3 3 2 2 RNA helicase KaiC PF06745.8 EGO57707.1 - 4.9e-07 29.0 0.8 0.22 10.5 0.0 3.6 2 1 1 3 3 3 2 KaiC DUF815 PF05673.8 EGO57707.1 - 1.4e-06 27.4 0.0 0.0081 15.1 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_18 PF13238.1 EGO57707.1 - 1.5e-06 28.5 0.0 0.086 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 EGO57707.1 - 1.8e-06 27.7 0.4 0.096 12.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain ResIII PF04851.10 EGO57707.1 - 2.3e-06 27.5 0.0 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EGO57707.1 - 3.5e-06 27.0 0.0 0.089 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 EGO57707.1 - 7.7e-06 24.9 0.1 0.043 12.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EGO57707.1 - 1e-05 25.6 0.0 0.045 13.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EGO57707.1 - 1.2e-05 25.0 0.0 4.1 7.0 0.0 4.0 2 2 1 3 3 3 0 Archaeal ATPase ABC_tran PF00005.22 EGO57707.1 - 1.4e-05 25.3 0.0 0.24 11.7 0.0 3.6 2 1 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.21 EGO57707.1 - 1.5e-05 24.5 0.1 0.16 11.4 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 EGO57707.1 - 1.5e-05 24.6 0.0 0.085 12.5 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Bac_DnaA PF00308.13 EGO57707.1 - 1.9e-05 24.3 0.0 0.15 11.6 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein Vps4_C PF09336.5 EGO57707.1 - 9.4e-05 22.2 0.1 0.0003 20.6 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain PhoH PF02562.11 EGO57707.1 - 0.00013 21.2 0.2 0.51 9.5 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 EGO57707.1 - 0.00017 21.1 0.0 0.57 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EGO57707.1 - 0.00019 21.1 0.0 0.5 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 EGO57707.1 - 0.0003 20.4 0.0 0.58 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EGO57707.1 - 0.00045 19.1 0.1 0.55 9.0 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain NTPase_1 PF03266.10 EGO57707.1 - 0.00064 19.4 0.3 0.65 9.6 0.0 4.0 3 0 0 3 3 3 1 NTPase DUF2075 PF09848.4 EGO57707.1 - 0.0015 17.5 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EGO57707.1 - 0.0054 16.2 0.0 0.28 10.6 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 EGO57707.1 - 0.0055 15.7 0.3 1.1 8.2 0.0 3.5 2 2 1 4 4 4 1 KAP family P-loop domain IPT PF01745.11 EGO57707.1 - 0.011 14.9 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 EGO57707.1 - 0.018 14.6 0.1 8.9 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EGO57707.1 - 0.029 13.2 0.0 1.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Zot PF05707.7 EGO57707.1 - 0.029 13.8 0.2 13 5.2 0.1 3.9 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 EGO57707.1 - 0.03 13.7 0.6 1.6 8.1 0.0 3.4 3 1 0 4 4 4 0 AAA-like domain AAA_23 PF13476.1 EGO57707.1 - 0.068 13.4 0.1 4.4 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 EGO57707.1 - 0.083 11.6 0.0 9.9 4.8 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase SKI PF01202.17 EGO57707.1 - 0.086 12.6 0.1 8.3 6.2 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase KTI12 PF08433.5 EGO57707.1 - 0.13 11.4 0.4 11 5.0 0.0 2.8 3 0 0 3 3 2 0 Chromatin associated protein KTI12 MobB PF03205.9 EGO57707.1 - 0.17 11.5 1.4 3.5 7.3 0.0 3.3 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B Fork_head PF00250.13 EGO57708.1 - 1.1e-33 115.0 0.2 2.8e-33 113.8 0.1 1.6 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EGO57708.1 - 4.6e-08 33.0 0.0 1.2e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 FHA domain CLU PF13236.1 EGO57710.1 - 2.4e-83 278.9 0.0 4.1e-83 278.1 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EGO57710.1 - 3.2e-52 176.8 2.7 5.6e-52 176.0 0.0 2.5 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EGO57710.1 - 1.5e-26 92.1 7.1 1.8e-12 46.9 0.1 3.7 1 1 1 3 3 3 3 Tetratricopeptide repeat CLU_N PF15044.1 EGO57710.1 - 7.5e-23 80.4 0.4 2.1e-22 79.0 0.1 2.0 2 0 0 2 2 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 EGO57710.1 - 4e-20 71.0 3.6 1.5e-05 24.7 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGO57710.1 - 4.5e-07 29.4 7.3 0.002 17.7 0.0 3.6 2 1 2 4 4 4 2 TPR repeat TPR_8 PF13181.1 EGO57710.1 - 0.00039 19.9 1.7 0.15 11.9 0.2 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EGO57710.1 - 0.0024 17.9 4.5 0.86 9.7 0.1 3.7 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EGO57710.1 - 0.0033 17.5 2.0 18 5.8 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGO57710.1 - 0.022 15.4 7.6 0.41 11.3 0.2 3.7 1 1 1 3 3 3 0 Tetratricopeptide repeat DUF727 PF05303.7 EGO57710.1 - 0.036 13.8 0.0 0.097 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF727) TPR_2 PF07719.12 EGO57710.1 - 0.038 13.9 12.6 1.9 8.6 0.2 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Ycf1 PF05758.7 EGO57710.1 - 0.06 11.0 3.9 0.084 10.5 2.7 1.2 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 EGO57710.1 - 0.063 13.0 4.1 0.16 11.7 2.8 1.6 1 0 0 1 1 1 0 DDHD domain TPR_14 PF13428.1 EGO57710.1 - 0.099 13.3 2.9 6.6 7.6 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat NPR3 PF03666.8 EGO57710.1 - 1.1 7.7 6.9 2.3 6.6 4.7 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TPR_4 PF07721.9 EGO57710.1 - 1.4 9.5 10.0 60 4.5 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Borrelia_P83 PF05262.6 EGO57710.1 - 3.1 5.9 17.7 6 5.0 12.2 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1993 PF09351.5 EGO57711.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) RXT2_N PF08595.6 EGO57711.1 - 0.57 9.9 10.8 6.7 6.4 0.3 2.9 3 0 0 3 3 3 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 EGO57711.1 - 7.3 6.0 15.5 14 5.2 0.5 2.3 2 0 0 2 2 2 0 Nucleoplasmin NAD_binding_6 PF08030.7 EGO57713.1 - 7.1e-20 71.4 0.0 1.5e-10 41.2 0.0 2.5 2 1 1 3 3 3 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EGO57713.1 - 1.5e-18 67.1 9.5 4.8e-18 65.4 6.6 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EGO57713.1 - 5.5e-13 48.7 0.0 1.9e-12 47.0 0.0 1.9 1 1 0 1 1 1 1 FAD-binding domain Yippee-Mis18 PF03226.9 EGO57714.1 - 9.4e-23 80.0 0.5 1.8e-22 79.2 0.1 1.7 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EGO57714.1 - 0.017 14.9 1.2 0.048 13.5 0.8 1.7 1 1 0 1 1 1 0 C-terminal domain of RIG-I BAF1_ABF1 PF04684.8 EGO57714.1 - 0.047 12.5 7.6 0.063 12.1 5.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2039 PF10217.4 EGO57714.1 - 0.24 11.4 0.1 0.24 11.4 0.0 2.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2039) Hid1 PF12722.2 EGO57714.1 - 5.1 4.6 9.0 6.7 4.2 6.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DHHW PF14286.1 EGO57714.1 - 6.9 5.8 7.9 12 5.1 5.5 1.4 1 1 0 1 1 1 0 DHHW protein Pap_E4 PF02711.9 EGO57714.1 - 8.1 7.3 8.5 15 6.4 5.9 1.5 1 0 0 1 1 1 0 E4 protein Nuc_sug_transp PF04142.10 EGO57715.1 - 1.3e-09 37.5 0.3 2.2e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EGO57715.1 - 5.8e-07 29.6 23.0 0.00016 21.7 3.4 3.2 2 1 1 3 3 3 3 EamA-like transporter family TPT PF03151.11 EGO57715.1 - 0.16 11.6 19.6 0.89 9.1 3.6 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF2985 PF11204.3 EGO57716.1 - 3.6e-35 119.5 1.6 3.6e-35 119.5 1.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Sen15 PF09631.5 EGO57717.1 - 9.2e-27 93.2 0.1 2e-26 92.1 0.0 1.6 2 0 0 2 2 2 1 Sen15 protein ADH_N PF08240.7 EGO57718.1 - 4.1e-28 97.3 0.3 7.3e-28 96.5 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO57718.1 - 2.1e-19 69.3 0.1 5.8e-19 67.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EGO57718.1 - 2.5e-05 23.7 0.3 8.3e-05 22.1 0.2 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Zip PF02535.17 EGO57719.1 - 4.8e-27 94.7 3.0 1e-26 93.6 2.1 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Endonuclease_NS PF01223.18 EGO57720.1 - 2.3e-63 213.5 0.0 2.8e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease BSMAP PF12280.3 EGO57721.1 - 0.013 15.3 1.3 0.016 15.0 0.9 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein Tmemb_170 PF10190.4 EGO57723.1 - 3.3e-05 23.8 3.9 4e-05 23.6 2.7 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF4118 PF13493.1 EGO57723.1 - 1.2 9.3 11.3 1.9 8.7 7.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4118) MBOAT PF03062.14 EGO57724.1 - 1.1e-20 74.0 16.5 3.3e-20 72.4 11.4 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EGO57724.1 - 3.2e-05 23.8 2.9 0.0001 22.3 2.0 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF912 PF06024.7 EGO57724.1 - 0.025 14.5 0.1 0.099 12.6 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WD40 PF00400.27 EGO57726.1 - 2.2e-49 163.6 25.0 4.1e-09 35.9 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGO57726.1 - 0.028 13.1 0.0 0.24 10.0 0.1 2.4 3 1 0 3 3 3 0 Nup133 N terminal like eIF2A PF08662.6 EGO57726.1 - 0.068 12.8 0.0 4.9 6.8 0.0 2.6 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A zf-C2H2 PF00096.21 EGO57727.1 - 2.1e-27 93.7 40.6 0.0011 19.2 0.1 9.5 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO57727.1 - 8.2e-21 72.7 36.3 0.0066 16.6 0.1 9.4 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGO57727.1 - 2.4e-17 62.2 42.1 1.7e-05 24.8 0.6 9.9 10 0 0 10 10 10 5 Zinc-finger double domain zf-met PF12874.2 EGO57727.1 - 0.0006 19.9 15.3 0.61 10.3 0.0 6.7 7 0 0 7 7 7 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EGO57727.1 - 0.0021 18.1 31.1 0.013 15.6 2.6 7.3 5 2 2 7 7 7 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EGO57727.1 - 0.0072 16.4 30.3 1.6 8.9 0.5 9.0 9 0 0 9 9 9 1 Zinc-finger double-stranded RNA-binding RNA_pol_Rpb6 PF01192.17 EGO57728.1 - 7.4e-24 83.2 0.2 1.2e-23 82.5 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.7 EGO57728.1 - 0.069 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit WSC PF01822.14 EGO57729.1 - 5.4e-37 125.5 25.9 1.3e-20 73.1 8.2 5.0 4 1 0 4 4 4 2 WSC domain PCI PF01399.22 EGO57730.1 - 1.9e-07 31.3 0.1 1.9e-07 31.3 0.0 2.9 3 0 0 3 3 3 1 PCI domain zf-ZPR1 PF03367.8 EGO57730.1 - 6.3 5.9 10.3 0.62 9.2 0.3 2.9 2 0 0 2 2 2 0 ZPR1 zinc-finger domain G-gamma PF00631.17 EGO57731.1 - 3.7e-28 97.0 0.1 4.5e-28 96.7 0.1 1.1 1 0 0 1 1 1 1 GGL domain Rdx PF10262.4 EGO57732.1 - 3e-28 97.6 0.7 5.5e-28 96.8 0.0 1.8 2 1 0 2 2 2 1 Rdx family SAGA-Tad1 PF12767.2 EGO57732.1 - 0.043 13.4 3.8 0.053 13.1 2.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF694 PF05107.7 EGO57732.1 - 0.051 12.7 2.3 0.079 12.1 1.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF694) Agouti PF05039.7 EGO57732.1 - 0.56 10.5 4.4 1.1 9.6 3.1 1.5 1 0 0 1 1 1 0 Agouti protein DHHW PF14286.1 EGO57732.1 - 0.67 9.1 7.3 14 4.9 4.4 2.1 2 0 0 2 2 2 0 DHHW protein Presenilin PF01080.12 EGO57732.1 - 0.81 8.4 5.4 1.1 8.0 3.7 1.1 1 0 0 1 1 1 0 Presenilin Calpain_inhib PF00748.14 EGO57732.1 - 1.7 8.9 9.1 2.1 8.6 5.2 1.9 2 1 0 2 2 2 0 Calpain inhibitor Hid1 PF12722.2 EGO57732.1 - 2.2 5.8 7.1 2.4 5.7 4.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Metallophos PF00149.23 EGO57733.1 - 1.2e-44 152.0 0.2 1.5e-44 151.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-HC5HC2H_2 PF13832.1 EGO57734.1 - 1e-34 118.8 6.7 1e-34 118.8 4.7 2.8 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EGO57734.1 - 5.7e-28 96.8 6.4 5.7e-28 96.8 4.4 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 EGO57734.1 - 2.8e-18 66.6 1.2 2.8e-18 66.6 0.8 2.4 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 EGO57734.1 - 3e-14 52.0 2.1 3e-14 52.0 1.4 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EGO57734.1 - 2e-09 36.9 23.0 9.2e-08 31.6 6.7 2.8 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 EGO57734.1 - 3.7 7.6 22.5 0.063 13.2 4.1 2.8 2 0 0 2 2 2 0 RING-like domain LRR_4 PF12799.2 EGO57736.1 - 4.3e-18 64.5 2.1 4.5e-05 22.9 0.5 4.1 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO57736.1 - 2.1e-14 52.9 5.2 6.8e-09 35.3 1.3 3.2 2 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EGO57736.1 - 2.8e-11 41.8 5.3 0.74 10.0 0.0 6.9 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EGO57736.1 - 1.2e-06 27.7 7.1 2.9 8.4 0.0 7.0 7 0 0 7 7 7 1 Leucine rich repeat LRR_6 PF13516.1 EGO57736.1 - 3.1e-06 26.7 1.8 2.9 8.2 0.0 5.6 5 0 0 5 5 5 2 Leucine Rich repeat Biotin_lipoyl PF00364.17 EGO57740.1 - 2e-21 75.4 0.7 4.1e-21 74.3 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EGO57740.1 - 2e-08 33.7 0.2 6.9e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EGO57740.1 - 1.2e-05 24.8 0.1 6.8e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 EGO57740.1 - 0.077 12.1 0.1 0.27 10.3 0.0 1.9 1 1 0 1 1 1 0 HlyD family secretion protein QRPTase_N PF02749.11 EGO57740.1 - 0.12 12.2 0.0 0.39 10.5 0.0 1.9 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain CoA_transf_3 PF02515.12 EGO57742.1 - 6e-29 100.6 0.1 6.4e-26 90.7 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Fungal_trans PF04082.13 EGO57744.1 - 3.3e-29 101.5 0.0 6.2e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mak10 PF04112.8 EGO57744.1 - 0.0017 17.6 0.0 0.0035 16.5 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase META PF03724.11 EGO57744.1 - 0.15 11.8 0.0 0.53 10.1 0.0 1.9 1 1 0 1 1 1 0 META domain Dioxygenase_C PF00775.16 EGO57745.1 - 1.3e-48 164.6 0.0 2e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EGO57745.1 - 2.1e-10 40.4 0.0 3.4e-09 36.5 0.0 2.2 1 1 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EGO57745.1 - 5.9e-05 23.0 0.0 0.00018 21.5 0.0 1.8 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 EGO57745.1 - 0.038 14.0 0.0 0.061 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) OPT PF03169.10 EGO57747.1 - 4.6e-168 560.4 48.8 1.7e-87 294.3 13.9 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Form-deh_trans PF09163.6 EGO57747.1 - 0.029 13.8 0.5 0.13 11.8 0.4 2.2 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane DUF3270 PF11674.3 EGO57747.1 - 0.19 11.7 5.5 0.32 11.0 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) XPA_C PF05181.7 EGO57747.1 - 0.19 11.3 0.1 0.45 10.1 0.1 1.5 1 0 0 1 1 1 0 XPA protein C-terminus DUF4191 PF13829.1 EGO57747.1 - 6.3 5.8 6.3 1.7 7.6 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) ketoacyl-synt PF00109.21 EGO57748.1 - 2.4e-56 191.0 2.2 3.2e-56 190.6 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EGO57748.1 - 2.5e-33 114.4 2.0 1e-32 112.4 1.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EGO57748.1 - 0.00027 19.9 0.0 0.00064 18.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGO57748.1 - 0.18 11.2 2.4 1.4 8.3 0.3 3.2 3 1 0 3 3 3 0 Thiolase, C-terminal domain Ubiq_cyt_C_chap PF03981.7 EGO57749.1 - 3.2e-40 137.2 2.2 5e-40 136.6 1.5 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Gly_rich PF12810.2 EGO57749.1 - 0.01 15.4 2.7 0.015 14.8 1.9 1.1 1 0 0 1 1 1 0 Glycine rich protein DHFR_1 PF00186.14 EGO57750.1 - 4.9e-24 84.7 0.0 1.4e-23 83.2 0.0 1.8 1 1 0 1 1 1 1 Dihydrofolate reductase TPR_2 PF07719.12 EGO57750.1 - 6.2e-11 41.3 10.4 0.079 12.9 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGO57750.1 - 2.4e-07 30.7 11.9 0.63 10.8 0.1 6.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGO57750.1 - 3.2e-06 26.6 4.4 0.87 9.2 0.0 5.0 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 EGO57750.1 - 8.1e-06 25.2 10.1 0.47 10.1 0.0 5.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGO57750.1 - 0.0001 22.5 3.9 0.044 14.1 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO57750.1 - 0.0007 19.1 1.2 0.21 11.4 0.0 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGO57750.1 - 0.0012 18.9 7.6 0.01 15.9 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO57750.1 - 0.0053 16.4 3.2 19 5.3 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGO57750.1 - 0.0067 17.0 11.7 5 7.9 0.1 5.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO57750.1 - 0.012 15.5 8.6 38 4.2 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat RIX1 PF08167.7 EGO57751.1 - 1.1e-47 161.7 0.1 2e-47 160.9 0.1 1.4 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis Raptor_N PF14538.1 EGO57751.1 - 0.0093 15.8 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Glyco_hydro_16 PF00722.16 EGO57753.1 - 2.2e-11 43.3 0.7 4.3e-11 42.4 0.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MTBP_N PF14918.1 EGO57755.1 - 0.14 11.5 0.1 0.14 11.5 0.1 1.0 1 0 0 1 1 1 0 MDM2-binding DUF3412 PF11892.3 EGO57756.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3412) Dus PF01207.12 EGO57758.1 - 8.6e-56 189.0 0.0 1.6e-55 188.1 0.0 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOG2 PF10428.4 EGO57758.1 - 0.00021 20.1 2.2 0.00036 19.3 1.5 1.4 1 0 0 1 1 1 1 RAM signalling pathway protein Sporozoite_P67 PF05642.6 EGO57758.1 - 0.003 15.5 4.5 0.0052 14.7 3.1 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Dicty_REP PF05086.7 EGO57758.1 - 0.0093 13.7 9.2 0.017 12.9 6.4 1.4 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Pex14_N PF04695.8 EGO57758.1 - 1.3 9.0 9.4 2.5 8.1 5.5 2.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MIF4G PF02854.14 EGO57759.1 - 1.8e-24 86.3 0.7 1.8e-24 86.3 0.5 1.6 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EGO57759.1 - 1.7e-22 79.2 0.0 3e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 MA3 domain Sigma70_ner PF04546.8 EGO57759.1 - 0.5 9.9 9.1 0.89 9.1 6.3 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.1 EGO57759.1 - 0.92 9.1 5.0 1.9 8.1 3.4 1.5 1 0 0 1 1 1 0 FAM176 family DPM2 PF07297.7 EGO57760.1 - 1.4e-36 124.5 1.9 1.7e-36 124.3 1.3 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EGO57760.1 - 7e-06 25.6 0.7 8.1e-06 25.4 0.5 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 EGO57760.1 - 4.8e-05 23.1 0.2 4.8e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) Cytochrom_C_asm PF01578.15 EGO57760.1 - 0.0058 16.1 0.3 0.0058 16.1 0.2 1.0 1 0 0 1 1 1 1 Cytochrome C assembly protein COX14 PF14880.1 EGO57760.1 - 0.007 15.9 2.8 0.031 13.8 0.0 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF4083 PF13314.1 EGO57760.1 - 0.023 14.5 1.1 0.044 13.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF1049 PF06305.6 EGO57760.1 - 0.42 10.1 3.8 1.1 8.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) PHD PF00628.24 EGO57764.1 - 5.2e-05 22.8 2.4 5.2e-05 22.8 1.7 2.4 2 0 0 2 2 2 2 PHD-finger ING PF12998.2 EGO57764.1 - 0.0019 18.4 2.4 0.0042 17.3 0.0 2.8 2 1 0 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding DUF342 PF03961.8 EGO57765.1 - 3.4e-06 25.7 0.9 4e-06 25.5 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Bactofilin PF04519.8 EGO57765.1 - 0.00035 20.5 0.7 0.0029 17.5 0.4 2.4 1 1 1 2 2 2 2 Polymer-forming cytoskeletal Fil_haemagg_2 PF13332.1 EGO57765.1 - 0.0029 17.3 6.8 0.014 15.1 3.6 2.3 1 1 1 2 2 2 1 Haemagluttinin repeat MinC_C PF03775.11 EGO57765.1 - 0.013 15.0 1.3 0.69 9.5 0.0 2.8 2 1 1 3 3 3 0 Septum formation inhibitor MinC, C-terminal domain SWM_repeat PF13753.1 EGO57765.1 - 0.052 12.6 1.6 0.065 12.2 1.1 1.1 1 0 0 1 1 1 0 Putative flagellar system-associated repeat DUF748 PF05359.6 EGO57765.1 - 0.12 12.3 0.0 2.8 7.9 0.0 2.8 1 1 2 3 3 3 0 Domain of Unknown Function (DUF748) zf-C2H2 PF00096.21 EGO57767.1 - 0.013 15.7 3.4 0.038 14.3 2.4 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO57767.1 - 0.029 14.7 2.8 0.078 13.3 1.9 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGO57767.1 - 0.11 12.8 1.3 15 6.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 EGO57767.1 - 0.48 10.2 5.8 0.077 12.7 1.4 1.7 2 0 0 2 2 2 0 BED zinc finger DUF3602 PF12223.3 EGO57768.1 - 3.4e-17 62.5 11.8 4e-09 36.7 1.2 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DnaJ PF00226.26 EGO57769.1 - 1.8e-08 33.9 0.0 2.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EGO57769.1 - 8.6e-06 25.5 0.0 9.4e-06 25.4 0.0 1.3 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.1 EGO57769.1 - 5.2 6.4 10.1 0.13 11.5 0.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3918) RNase_H_2 PF13482.1 EGO57770.1 - 0.063 13.0 0.2 1.4 8.6 0.0 2.5 1 1 0 2 2 2 0 RNase_H superfamily Ku PF02735.11 EGO57771.1 - 3.9e-28 98.2 0.0 1.3e-27 96.5 0.0 1.9 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EGO57771.1 - 1e-25 90.5 0.2 1.6e-25 89.8 0.1 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EGO57771.1 - 4.7e-17 62.0 0.0 9.9e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like VWA PF00092.23 EGO57771.1 - 0.00016 21.4 0.1 0.00033 20.4 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EGO57771.1 - 0.001 19.2 0.1 0.0031 17.6 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain Ku_C PF03730.9 EGO57771.1 - 0.07 13.6 0.2 0.75 10.3 0.0 2.5 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm DUF4149 PF13664.1 EGO57772.1 - 2.1e-24 85.4 1.3 2.1e-24 85.4 0.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.6 EGO57772.1 - 0.0064 16.2 0.1 0.011 15.4 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) BDV_P10 PF06515.6 EGO57773.1 - 0.084 12.7 0.5 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 Borna disease virus P10 protein FliD_N PF02465.13 EGO57773.1 - 0.088 13.1 1.4 0.14 12.4 1.0 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF1295 PF06966.7 EGO57774.1 - 1.8e-41 141.9 9.1 2.2e-41 141.6 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EGO57774.1 - 0.068 13.3 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.15 EGO57775.1 - 1.5e-92 310.5 0.0 3.2e-87 292.9 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 EGO57775.1 - 7e-22 77.2 0.0 1.5e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Stb3 PF10330.4 EGO57777.1 - 7.6e-38 128.1 0.0 1.4e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein Herpeto_peptide PF14409.1 EGO57778.1 - 0.048 13.4 0.2 0.072 12.8 0.1 1.3 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Herpetosiphon LIN37 PF15306.1 EGO57779.1 - 0.00053 19.9 3.0 0.0013 18.6 2.1 1.6 1 0 0 1 1 1 1 LIN37 Glyco_hydro_76 PF03663.9 EGO57781.1 - 1.1e-52 179.6 9.1 1.3e-52 179.4 6.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EGO57781.1 - 1e-05 24.7 1.5 0.00062 18.8 1.4 2.3 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 EGO57781.1 - 7.1e-05 22.1 1.7 2.6 7.2 0.0 3.9 2 1 2 4 4 4 3 D-glucuronyl C5-epimerase C-terminus DUF1680 PF07944.7 EGO57781.1 - 0.00039 18.8 0.2 0.011 13.9 0.1 2.5 1 1 2 3 3 3 2 Putative glycosyl hydrolase of unknown function (DUF1680) Glucosamine_iso PF01182.15 EGO57783.1 - 9.7e-61 204.9 0.0 1.1e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hydrolase_6 PF13344.1 EGO57784.1 - 4e-29 100.4 0.0 6e-29 99.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO57784.1 - 6.4e-13 49.6 0.0 1.1e-12 48.9 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO57784.1 - 1.2e-11 44.1 0.0 4.2e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EGO57784.1 - 2.9e-06 27.6 0.1 0.001 19.3 0.1 2.8 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase SET PF00856.23 EGO57785.1 - 4.4e-08 33.5 0.1 0.00048 20.4 0.0 2.9 2 1 0 2 2 2 2 SET domain zf-MYND PF01753.13 EGO57785.1 - 0.021 14.6 5.0 0.021 14.6 3.5 2.1 2 0 0 2 2 2 0 MYND finger mono-CXXC PF15626.1 EGO57785.1 - 0.037 13.9 2.3 0.41 10.6 2.0 2.4 2 0 0 2 2 2 0 single CXXC unit DUF164 PF02591.10 EGO57785.1 - 0.3 10.9 2.7 0.46 10.3 0.2 2.4 2 0 0 2 2 2 0 Putative zinc ribbon domain DZR PF12773.2 EGO57785.1 - 0.62 9.9 12.1 0.043 13.6 3.9 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2 PF00096.21 EGO57786.1 - 3.4e-06 27.0 20.3 0.00012 22.1 4.4 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO57786.1 - 0.0022 18.1 6.8 0.0022 18.1 4.7 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO57786.1 - 0.01 16.0 2.8 0.01 16.0 1.9 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO57786.1 - 0.079 13.1 6.6 0.12 12.5 1.7 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding K_channel_TID PF07941.6 EGO57788.1 - 0.012 15.7 5.7 0.012 15.7 4.0 3.1 2 1 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF945 PF06097.6 EGO57788.1 - 0.035 12.8 1.4 0.058 12.1 0.9 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) zf-RING_2 PF13639.1 EGO57788.1 - 0.28 11.0 11.5 0.033 14.0 2.4 2.9 3 0 0 3 3 3 0 Ring finger domain Med3 PF11593.3 EGO57788.1 - 2.4 7.3 9.1 2.5 7.2 5.4 1.6 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Totivirus_coat PF05518.6 EGO57788.1 - 2.6 5.7 10.7 4 5.1 7.4 1.1 1 0 0 1 1 1 0 Totivirus coat protein Mito_fiss_reg PF05308.6 EGO57788.1 - 8.8 5.6 6.7 16 4.7 4.6 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF2361 PF10153.4 EGO57789.1 - 5.5e-38 129.6 11.5 5.5e-38 129.6 8.0 2.4 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2361) DUF2120 PF09893.4 EGO57789.1 - 0.023 14.6 0.4 0.046 13.6 0.2 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) CCDC-167 PF15188.1 EGO57789.1 - 0.91 9.5 8.6 0.61 10.0 3.8 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 YfdX PF10938.3 EGO57789.1 - 6 6.5 9.1 5.3 6.6 3.5 2.4 2 1 0 2 2 2 0 YfdX protein TPR_11 PF13414.1 EGO57791.1 - 2.4e-30 103.9 32.7 6.6e-07 28.8 0.1 10.0 9 1 0 9 9 9 5 TPR repeat TPR_1 PF00515.23 EGO57791.1 - 1.7e-27 93.8 31.4 0.00054 19.4 0.0 11.8 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.12 EGO57791.1 - 8.2e-27 90.9 34.3 0.0033 17.2 0.2 12.2 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 EGO57791.1 - 9.5e-26 89.5 19.1 4.2e-07 29.7 0.0 8.6 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGO57791.1 - 3.8e-21 73.2 25.6 0.00051 19.6 0.0 11.6 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 EGO57791.1 - 3e-20 72.3 27.2 8.9e-06 25.9 0.2 10.1 7 3 2 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 EGO57791.1 - 1e-15 57.9 47.4 2.2e-07 31.3 0.5 10.7 9 5 1 11 11 11 4 Tetratricopeptide repeat TPR_7 PF13176.1 EGO57791.1 - 8.3e-15 53.3 30.3 0.019 14.7 0.0 11.2 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGO57791.1 - 2.3e-12 46.3 48.1 0.00092 19.6 0.0 12.7 12 3 3 15 15 11 4 Tetratricopeptide repeat TPR_6 PF13174.1 EGO57791.1 - 5.2e-09 35.9 27.4 0.013 15.8 0.0 10.4 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGO57791.1 - 1.1e-08 34.5 12.7 0.063 13.4 0.1 10.4 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGO57791.1 - 7.3e-06 25.7 3.1 10 6.0 0.1 6.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGO57791.1 - 3.6e-05 23.5 20.1 0.46 10.4 0.1 9.7 10 0 0 10 10 10 2 Tetratricopeptide repeat Homeobox_KN PF05920.6 EGO57793.1 - 6.7e-19 67.3 2.3 5.7e-18 64.3 0.3 2.5 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 EGO57793.1 - 4.2e-06 26.2 0.7 7.9e-06 25.4 0.5 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox PF00046.24 EGO57795.1 - 6.7e-09 35.2 0.5 4.1e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Homeobox domain Rhodanese PF00581.15 EGO57795.1 - 1.1e-07 32.1 0.0 4.1e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain DUF3763 PF12592.3 EGO57795.1 - 0.046 13.3 0.2 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) Peptidase_C14 PF00656.17 EGO57795.1 - 0.075 12.7 0.0 0.36 10.4 0.0 1.8 1 1 0 1 1 1 0 Caspase domain PIG-X PF08320.7 EGO57796.1 - 2.6e-70 235.9 0.0 4.8e-70 235.0 0.0 1.5 1 0 0 1 1 1 1 PIG-X / PBN1 Sulfotransfer_3 PF13469.1 EGO57797.1 - 5.6e-06 27.3 0.1 8.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Mhr1 PF12829.2 EGO57798.1 - 4.7e-31 106.4 0.1 7.5e-31 105.8 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DUF3437 PF11919.3 EGO57798.1 - 0.015 14.9 0.1 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) N2227 PF07942.7 EGO57798.1 - 0.028 13.3 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein AAA_2 PF07724.9 EGO57799.1 - 1.6e-48 164.8 0.0 2.7e-46 157.5 0.0 3.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EGO57799.1 - 1.9e-28 99.2 0.3 1e-15 58.1 0.0 3.3 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EGO57799.1 - 4.2e-23 81.0 1.8 1.7e-22 79.1 1.2 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EGO57799.1 - 3.5e-17 62.4 0.0 1.7e-10 40.7 0.0 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGO57799.1 - 1.5e-16 60.9 17.4 5.7e-06 26.4 0.0 7.0 3 2 2 7 7 7 2 AAA ATPase domain AAA_22 PF13401.1 EGO57799.1 - 2.9e-15 56.5 0.1 3.3e-05 24.0 0.0 4.3 3 1 1 4 4 3 2 AAA domain Sigma54_activat PF00158.21 EGO57799.1 - 1.1e-09 38.0 0.0 1.5e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 EGO57799.1 - 4.5e-09 37.1 5.8 0.00094 19.9 0.0 3.9 2 2 0 3 3 3 2 AAA domain AAA_14 PF13173.1 EGO57799.1 - 2.4e-08 33.9 0.0 0.011 15.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 EGO57799.1 - 3.1e-07 29.9 0.0 0.016 14.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EGO57799.1 - 6.5e-07 29.0 1.8 0.033 13.9 0.0 3.5 3 0 0 3 3 2 2 Part of AAA domain Clp_N PF02861.15 EGO57799.1 - 2.3e-06 27.4 14.6 2.4e-05 24.1 0.0 4.7 5 0 0 5 5 3 1 Clp amino terminal domain AAA_18 PF13238.1 EGO57799.1 - 7.3e-06 26.3 7.2 0.0084 16.4 0.1 4.2 4 1 0 4 4 3 2 AAA domain Mg_chelatase PF01078.16 EGO57799.1 - 8.1e-06 25.1 0.1 0.16 11.1 0.0 3.6 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EGO57799.1 - 1.9e-05 24.5 9.6 0.011 15.4 0.2 5.2 2 2 3 5 5 5 1 Archaeal ATPase AAA_33 PF13671.1 EGO57799.1 - 3.1e-05 23.8 0.0 0.21 11.4 0.0 3.2 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EGO57799.1 - 5.9e-05 23.2 0.0 0.46 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EGO57799.1 - 7.1e-05 22.8 3.4 0.26 11.2 0.0 4.0 4 1 1 5 5 2 2 AAA domain AAA_3 PF07726.6 EGO57799.1 - 0.00017 21.2 0.0 0.97 9.0 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EGO57799.1 - 0.00017 20.5 0.1 0.018 13.9 0.0 2.8 2 1 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 EGO57799.1 - 0.0002 21.0 0.0 0.85 9.3 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EGO57799.1 - 0.0003 20.2 0.6 1.8 7.9 0.0 3.8 3 1 0 4 4 4 2 AAA domain ABC_tran PF00005.22 EGO57799.1 - 0.00041 20.6 0.5 0.77 10.0 0.0 3.5 3 0 0 3 3 3 1 ABC transporter ResIII PF04851.10 EGO57799.1 - 0.00058 19.7 0.6 0.18 11.6 0.0 3.6 3 1 1 4 4 3 1 Type III restriction enzyme, res subunit Torsin PF06309.6 EGO57799.1 - 0.00085 19.2 0.0 0.0053 16.6 0.0 2.1 2 0 0 2 2 2 1 Torsin DUF258 PF03193.11 EGO57799.1 - 0.0009 18.4 0.0 0.48 9.5 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGO57799.1 - 0.0011 18.4 0.0 0.98 8.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.1 EGO57799.1 - 0.0015 18.1 0.0 1.2 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EGO57799.1 - 0.0032 17.1 0.0 0.29 10.8 0.0 3.4 3 0 0 3 3 3 1 NTPase NACHT PF05729.7 EGO57799.1 - 0.0033 17.0 0.0 0.36 10.4 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 EGO57799.1 - 0.015 14.7 11.9 0.19 11.1 0.0 5.2 4 3 1 5 5 5 0 AAA-like domain SRP54 PF00448.17 EGO57799.1 - 0.024 14.0 0.0 6.3 6.1 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_21 PF13304.1 EGO57799.1 - 0.028 14.4 0.4 2.2 8.1 0.0 2.9 4 0 0 4 4 2 0 AAA domain UPF0079 PF02367.12 EGO57799.1 - 0.034 13.7 0.0 8.7 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 EGO57799.1 - 0.044 13.7 0.7 3 7.8 0.0 3.6 3 2 0 3 3 3 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EGO57799.1 - 0.072 12.6 0.0 8.6 5.8 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein V_ATPase_I PF01496.14 EGO57799.1 - 0.074 10.9 5.9 0.15 9.8 4.1 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PduV-EutP PF10662.4 EGO57799.1 - 0.089 12.2 0.0 6.8 6.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IncA PF04156.9 EGO57799.1 - 0.12 11.9 10.6 0.4 10.2 7.3 1.9 1 0 0 1 1 1 0 IncA protein Peptidase_M16 PF00675.15 EGO57799.1 - 0.28 10.9 4.4 2.3 7.9 0.0 2.7 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Macoilin PF09726.4 EGO57799.1 - 1.3 7.2 13.6 2.2 6.4 9.4 1.3 1 0 0 1 1 1 0 Transmembrane protein Atg14 PF10186.4 EGO57799.1 - 3.4 6.5 9.3 7.8 5.3 6.5 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 UPF0113 PF03657.8 EGO57800.1 - 9.3e-07 28.6 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 EGO57800.1 - 0.011 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 pre-rRNA processing and ribosome biogenesis PUA PF01472.15 EGO57800.1 - 0.029 14.0 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 PUA domain AA_kinase PF00696.23 EGO57801.1 - 1.1e-41 142.9 1.5 1.9e-41 142.1 1.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EGO57801.1 - 2.2e-14 52.8 0.2 6.2e-14 51.4 0.0 1.9 2 0 0 2 2 2 1 PUA domain Peptidase_M76 PF09768.4 EGO57802.1 - 1.3e-62 210.3 1.2 1.9e-62 209.7 0.8 1.3 1 0 0 1 1 1 1 Peptidase M76 family DUF2268 PF10026.4 EGO57802.1 - 0.01 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) SprT-like PF10263.4 EGO57802.1 - 0.01 15.4 1.0 0.01 15.4 0.7 2.0 2 2 1 3 3 3 0 SprT-like family Tox-MPTase2 PF15638.1 EGO57802.1 - 0.081 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Peptidase_MA_2 PF13485.1 EGO57802.1 - 0.093 12.7 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Dicty_spore_N PF04562.7 EGO57802.1 - 0.097 12.9 0.6 1.9 8.8 0.2 2.3 1 1 1 2 2 2 0 Dictyostelium spore coat protein, N terminus Pkinase PF00069.20 EGO57803.1 - 2.5e-71 239.9 0.0 3.1e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57803.1 - 2e-44 151.6 0.0 2.6e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO57803.1 - 5.3e-07 28.8 0.0 1.3e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGO57803.1 - 0.00052 19.1 0.1 0.00086 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGO57803.1 - 0.014 14.7 0.0 0.058 12.7 0.0 1.9 1 1 1 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.4 EGO57803.1 - 0.045 13.0 0.0 0.085 12.1 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EGO57803.1 - 0.098 12.3 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TIP41 PF04176.8 EGO57804.1 - 1.3e-75 252.6 0.0 1.9e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family DUF3439 PF11921.3 EGO57804.1 - 2.2 8.0 5.3 5.3 6.8 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FUN14 PF04930.10 EGO57806.1 - 2.8e-07 30.7 4.8 1.4e-05 25.2 3.4 2.5 1 1 0 1 1 1 1 FUN14 family Peptidase_M24 PF00557.19 EGO57808.1 - 2.2e-43 148.2 0.0 3.1e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EGO57808.1 - 1.3e-26 93.6 0.0 3.6e-20 72.7 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain tRNA-synt_1b PF00579.20 EGO57809.1 - 6.5e-49 166.6 0.0 6.5e-25 87.8 0.0 2.5 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.17 EGO57810.1 - 5.7e-23 80.5 0.0 9.5e-23 79.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Fcf2 PF08698.6 EGO57811.1 - 2.2e-29 101.3 0.5 4.1e-29 100.5 0.0 1.7 2 1 0 2 2 2 1 Fcf2 pre-rRNA processing CBFD_NFYB_HMF PF00808.18 EGO57812.1 - 9.7e-20 70.4 0.6 1.9e-19 69.4 0.4 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGO57812.1 - 3.8e-11 42.9 1.2 3.8e-11 42.9 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EGO57812.1 - 0.026 14.3 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.7 EGO57813.1 - 4.3e-120 400.7 3.1 1.1e-119 399.4 2.1 1.7 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.1 EGO57813.1 - 0.00017 21.0 4.0 0.00017 21.0 2.8 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) COG5 PF10392.4 EGO57813.1 - 0.013 15.4 5.3 0.071 13.0 2.2 2.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 COG2 PF06148.6 EGO57813.1 - 0.11 12.3 15.3 0.22 11.3 2.1 4.2 3 1 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 RRM_2 PF04059.7 EGO57814.1 - 2.1e-06 27.6 0.1 4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_6 PF14259.1 EGO57814.1 - 0.098 12.6 0.1 10 6.1 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sad1_UNC PF07738.8 EGO57815.1 - 1.2e-37 128.7 0.1 2.2e-37 127.8 0.1 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal NRDE-2 PF08424.5 EGO57816.1 - 5.9e-99 330.9 0.1 5.9e-99 330.9 0.1 2.6 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.1 EGO57816.1 - 0.00011 22.7 0.4 8.2 7.2 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Voltage_CLC PF00654.15 EGO57819.1 - 4e-95 318.8 20.4 4e-95 318.8 14.1 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel TAT_signal PF10518.4 EGO57819.1 - 0.014 15.3 3.4 0.014 15.3 2.4 3.0 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Peptidase_M18 PF02127.10 EGO57820.1 - 1.2e-168 561.1 0.0 1.4e-168 560.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EGO57820.1 - 9.4e-05 21.3 0.0 0.00029 19.7 0.0 1.8 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase Ycf1 PF05758.7 EGO57822.1 - 0.007 14.1 32.0 0.012 13.4 8.3 2.1 2 0 0 2 2 2 2 Ycf1 SAPS PF04499.10 EGO57822.1 - 0.075 11.6 32.7 0.48 8.9 6.8 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SPX PF03105.14 EGO57822.1 - 0.1 12.3 38.7 0.078 12.7 7.1 3.2 3 0 0 3 3 3 0 SPX domain CDC45 PF02724.9 EGO57822.1 - 0.11 10.4 32.3 0.17 9.8 5.2 2.1 2 0 0 2 2 2 0 CDC45-like protein Raftlin PF15250.1 EGO57822.1 - 4.7 5.6 42.3 0.4 9.1 9.2 2.3 2 0 0 2 2 2 0 Raftlin Mem_trans PF03547.13 EGO57822.1 - 5.4 5.2 14.3 1.3 7.2 0.4 2.3 2 0 0 2 2 2 0 Membrane transport protein Otopetrin PF03189.8 EGO57822.1 - 8 5.3 15.7 3 6.7 2.5 2.2 2 0 0 2 2 2 0 Otopetrin RR_TM4-6 PF06459.7 EGO57822.1 - 8.7 6.1 48.1 16 5.3 16.9 3.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Whi5 PF08528.6 EGO57823.1 - 5.4e-10 38.6 0.1 1.1e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Whi5 like Erf4 PF10256.4 EGO57824.1 - 2.7e-28 98.2 0.0 3.8e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4203 PF13886.1 EGO57828.1 - 8.1e-10 38.5 19.9 1e-09 38.2 13.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Bax1-I PF01027.15 EGO57828.1 - 0.028 14.0 12.7 0.035 13.7 8.8 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 SPC12 PF06645.8 EGO57828.1 - 2.9 7.7 10.7 1.3 8.8 2.3 2.5 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2142 PF09913.4 EGO57828.1 - 4 6.0 12.4 0.035 12.7 1.3 2.4 1 1 2 3 3 3 0 Predicted membrane protein (DUF2142) FA_hydroxylase PF04116.8 EGO57828.1 - 10 6.5 9.3 1.5e+02 2.8 6.4 2.3 1 1 0 1 1 1 0 Fatty acid hydroxylase superfamily AMP-binding PF00501.23 EGO57829.1 - 1e-72 244.8 0.0 1.3e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO57829.1 - 2.1e-16 60.5 0.0 4.4e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro_1 PF00232.13 EGO57830.1 - 3.1e-155 516.8 0.0 3.7e-155 516.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 GFA PF04828.9 EGO57831.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme SSrecog PF03531.9 EGO57832.1 - 2e-74 249.7 0.1 5.7e-74 248.1 0.1 1.8 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EGO57832.1 - 4.1e-25 87.5 0.0 3.3e-24 84.6 0.0 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF2201_N PF13203.1 EGO57832.1 - 0.026 13.7 0.0 0.026 13.7 0.0 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain Xpo1 PF08389.7 EGO57833.1 - 6e-42 143.0 4.7 5.1e-41 140.0 0.3 3.3 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 EGO57833.1 - 3.3e-06 26.7 1.6 1.2 9.4 0.1 4.6 4 0 0 4 4 4 3 HEAT repeat RIX1 PF08167.7 EGO57833.1 - 0.096 12.3 1.3 1.1e+02 2.4 0.1 4.5 4 1 1 5 5 5 0 rRNA processing/ribosome biogenesis CDP-OH_P_transf PF01066.16 EGO57835.1 - 8.8e-17 61.2 5.2 8.8e-17 61.2 3.6 1.5 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GIDA PF01134.17 EGO57836.1 - 3.8e-157 523.1 0.0 4.6e-157 522.8 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EGO57836.1 - 3.9e-15 55.6 0.0 9.8e-15 54.3 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 FAD_oxidored PF12831.2 EGO57836.1 - 1.3e-07 31.0 0.1 2e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO57836.1 - 1.1e-06 28.7 0.2 2.6e-06 27.4 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO57836.1 - 0.00018 20.5 1.2 0.26 10.1 0.5 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO57836.1 - 0.0023 16.8 6.6 0.0044 15.9 4.1 1.9 1 1 1 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 EGO57836.1 - 0.0024 17.4 0.3 0.0043 16.6 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EGO57836.1 - 0.048 12.1 0.8 0.24 9.8 0.6 1.9 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.1 EGO57836.1 - 0.089 13.0 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DJ-1_PfpI PF01965.19 EGO57836.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Pyr_redox_3 PF13738.1 EGO57836.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO57836.1 - 0.2 12.0 0.8 0.47 10.8 0.6 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SSB PF00436.20 EGO57837.1 - 1.5e-19 69.7 0.0 1.8e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.10 EGO57838.1 - 1.1e-28 100.1 8.9 1.6e-24 86.5 1.2 2.2 1 1 1 2 2 2 2 Pheromone A receptor CAP_N PF01213.14 EGO57838.1 - 2.6 7.2 8.1 1.4 8.1 0.7 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PBD PF00786.23 EGO57840.1 - 0.0019 18.5 0.4 0.009 16.4 0.1 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain HLH PF00010.21 EGO57843.1 - 3.8e-11 42.5 0.0 8.9e-11 41.3 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.8 EGO57843.1 - 1.8 8.3 14.2 0.55 10.0 3.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Histone PF00125.19 EGO57844.1 - 5.5e-29 100.0 0.7 7.6e-29 99.6 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGO57844.1 - 8.8e-05 22.6 0.1 0.00013 22.1 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGO57844.1 - 0.012 15.6 0.3 0.021 14.9 0.2 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EGO57844.1 - 0.077 12.2 0.1 0.077 12.2 0.1 1.8 1 1 0 2 2 2 0 Centromere kinetochore component CENP-T DER1 PF04511.10 EGO57845.1 - 5.3e-51 172.9 6.0 6e-51 172.7 4.2 1.0 1 0 0 1 1 1 1 Der1-like family ARD PF03079.9 EGO57846.1 - 1.9e-43 148.1 0.2 2.4e-43 147.7 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EGO57846.1 - 3.8e-08 32.7 0.0 6.1e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EGO57846.1 - 7.9e-06 25.5 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EGO57846.1 - 0.05 13.0 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Cupin adh_short PF00106.20 EGO57847.1 - 3.8e-24 85.4 0.0 5.2e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO57847.1 - 1.5e-12 47.5 0.0 2.1e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO57847.1 - 3.6e-08 33.1 0.0 7.4e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EGO57847.1 - 1.1e-06 28.6 0.0 1.4e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EGO57847.1 - 5.7e-06 25.4 0.0 7.1e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EGO57847.1 - 0.00065 18.4 0.0 0.00094 17.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGO57847.1 - 0.0047 15.8 0.0 0.01 14.7 0.0 1.6 1 0 0 1 1 1 1 RmlD substrate binding domain Saccharop_dh PF03435.13 EGO57847.1 - 0.0055 15.7 0.0 0.0077 15.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 EGO57847.1 - 0.0056 15.9 0.0 0.015 14.5 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EGO57847.1 - 0.019 14.9 0.0 0.046 13.7 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding F420_oxidored PF03807.12 EGO57847.1 - 0.031 14.6 0.0 0.057 13.8 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ribosomal_S21 PF01165.15 EGO57848.1 - 0.93 8.9 9.9 4.4 6.8 6.9 1.9 1 1 0 1 1 1 0 Ribosomal protein S21 DUF3435 PF11917.3 EGO57848.1 - 1.3 7.7 5.1 1.4 7.5 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Atg14 PF10186.4 EGO57848.1 - 2.2 7.1 6.1 2.5 6.9 4.3 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_11 PF13086.1 EGO57848.1 - 5.2 6.5 6.3 5.7 6.4 4.3 1.0 1 0 0 1 1 1 0 AAA domain ATP11 PF06644.6 EGO57848.1 - 5.2 6.4 10.4 5.1 6.4 7.2 1.0 1 0 0 1 1 1 0 ATP11 protein DUF4337 PF14235.1 EGO57848.1 - 6.5 6.5 9.1 7.5 6.3 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) OmpH PF03938.9 EGO57848.1 - 7.5 6.4 9.6 8.8 6.2 6.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) His_biosynth PF00977.16 EGO57849.1 - 1.5e-35 122.5 0.0 1.9e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 EGO57849.1 - 0.078 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Aldolase PF01081.14 EGO57849.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 KDPG and KHG aldolase PcrB PF01884.12 EGO57849.1 - 0.15 11.2 0.0 0.3 10.3 0.0 1.6 1 0 0 1 1 1 0 PcrB family DUF4602 PF15375.1 EGO57850.1 - 0.00029 20.9 8.8 0.00029 20.9 6.1 4.1 2 1 2 4 4 4 1 Domain of unknown function (DUF4602) COPI_C PF06957.6 EGO57850.1 - 1.1 7.7 7.6 1.9 6.9 5.3 1.5 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Anillin PF08174.6 EGO57851.1 - 3.6e-35 121.0 0.2 1.5e-34 119.0 0.1 2.2 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EGO57851.1 - 1.4e-07 31.6 0.0 4.8e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 PH domain Pyr_redox_2 PF07992.9 EGO57852.1 - 1e-46 159.3 0.0 1.4e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO57852.1 - 4.1e-13 49.5 0.0 4.9e-11 42.8 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO57852.1 - 2.9e-05 24.2 0.0 0.16 11.9 0.0 3.3 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase DUF3006 PF11213.3 EGO57852.1 - 0.11 12.3 0.1 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) Trehalase_Ca-bi PF07492.6 EGO57852.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain Peptidase_M24 PF00557.19 EGO57853.1 - 5.5e-28 97.9 0.1 2.5e-16 59.8 0.0 2.3 2 0 0 2 2 2 2 Metallopeptidase family M24 AMP_N PF05195.11 EGO57853.1 - 3.5e-19 68.5 0.0 1.1e-18 66.8 0.0 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Zn_clus PF00172.13 EGO57854.1 - 2.9e-11 43.0 13.8 5.6e-11 42.1 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGO57854.1 - 5.5e-09 35.2 0.0 3.4e-05 22.8 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain DUF2763 PF10961.3 EGO57854.1 - 0.017 15.4 0.2 0.017 15.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) RPN7 PF10602.4 EGO57855.1 - 3.8e-49 166.4 0.0 6e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EGO57855.1 - 1.6e-16 60.5 0.0 3.8e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 EGO57855.1 - 0.022 14.6 1.0 2 8.5 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Prp18 PF02840.10 EGO57856.1 - 9.5e-52 174.6 0.0 9.5e-52 174.6 0.0 1.7 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EGO57856.1 - 1.6e-11 43.2 0.2 1.6e-11 43.2 0.2 2.8 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like CAF-1_p150 PF11600.3 EGO57856.1 - 0.0046 16.3 17.9 0.0088 15.4 12.4 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 EGO57856.1 - 0.14 11.3 15.7 0.22 10.6 10.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RNA_pol_3_Rpc31 PF11705.3 EGO57856.1 - 3.1 7.6 10.8 5.9 6.7 7.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Med3 PF11593.3 EGO57856.1 - 3.2 6.8 7.2 1.7 7.8 3.8 1.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal NAM-associated PF14303.1 EGO57856.1 - 4.7 7.5 14.0 6.1 7.1 8.4 2.0 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain SAP18 PF06487.7 EGO57857.1 - 1.4e-32 112.0 0.0 1.7e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Abhydrolase_6 PF12697.2 EGO57858.1 - 1.1e-05 25.4 0.1 3.8e-05 23.6 0.0 2.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family LCAT PF02450.10 EGO57858.1 - 5.1e-05 22.4 1.6 0.00023 20.2 0.0 2.2 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 EGO57858.1 - 0.0027 17.3 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EGO57858.1 - 0.0066 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lectin_leg-like PF03388.8 EGO57859.1 - 2.2e-24 85.8 0.0 6.8e-24 84.2 0.0 1.7 2 0 0 2 2 2 1 Legume-like lectin family FlaC_arch PF05377.6 EGO57859.1 - 0.099 12.5 0.6 5.5 6.9 0.2 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PHD_3 PF13922.1 EGO57859.1 - 0.38 11.0 4.0 0.73 10.1 2.8 1.5 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Alg6_Alg8 PF03155.10 EGO57861.1 - 1.7e-142 475.6 27.3 2.1e-142 475.3 18.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.4 EGO57862.1 - 1.8e-22 79.4 1.1 1.5e-13 50.8 0.0 3.4 2 1 1 3 3 3 2 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EGO57862.1 - 5.2e-19 67.7 0.7 8.5e-19 67.0 0.5 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EGO57862.1 - 1.4e-14 53.3 0.5 2.8e-14 52.3 0.4 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EGO57862.1 - 2.3e-06 27.2 0.1 6.8e-06 25.7 0.1 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 EGO57862.1 - 3.3e-05 23.5 0.1 9.7e-05 22.1 0.1 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Fijivirus_P9-2 PF06837.6 EGO57862.1 - 0.31 10.1 0.0 0.55 9.3 0.0 1.3 1 0 0 1 1 1 0 Fijivirus P9-2 protein Claudin_2 PF13903.1 EGO57863.1 - 0.012 15.2 3.9 0.015 14.9 2.2 1.5 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction MIG-14_Wnt-bd PF06664.7 EGO57863.1 - 0.015 14.1 2.7 0.02 13.7 1.9 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF3169 PF11368.3 EGO57863.1 - 0.13 11.4 4.1 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Pox_A14 PF05767.7 EGO57863.1 - 0.34 10.9 3.4 1.6 8.7 1.4 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 HK PF02110.10 EGO57864.1 - 2.4e-77 259.4 0.1 3.6e-77 258.8 0.1 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EGO57864.1 - 8.2e-57 191.2 1.9 1.3e-56 190.6 1.3 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 EGO57864.1 - 0.00014 21.2 0.1 0.00031 20.1 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 EGO57864.1 - 0.002 17.3 0.0 0.0046 16.1 0.0 1.6 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Peripla_BP_6 PF13458.1 EGO57864.1 - 0.0024 17.2 0.4 0.015 14.6 0.1 2.3 1 1 1 2 2 2 1 Periplasmic binding protein ADH_zinc_N PF00107.21 EGO57864.1 - 0.049 13.1 1.1 1.2 8.7 0.0 3.0 2 1 1 3 3 3 0 Zinc-binding dehydrogenase DUF2347 PF09804.4 EGO57865.1 - 2.4e-103 345.2 0.0 3.1e-103 344.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EGO57865.1 - 6.4e-58 195.7 0.0 1.6e-57 194.3 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 EGO57865.1 - 3.3e-05 23.5 0.1 0.0002 21.0 0.0 2.0 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EGO57865.1 - 0.003 16.1 0.0 0.036 12.5 0.0 2.1 2 0 0 2 2 2 1 Transport protein Avl9 Herpes_BLLF1 PF05109.8 EGO57865.1 - 1.8 6.4 11.8 2.6 5.9 8.2 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Acyltransferase PF01553.16 EGO57866.1 - 3.8e-33 113.7 0.0 6.3e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ribonuc_L-PSP PF01042.16 EGO57866.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Endoribonuclease L-PSP Sec63 PF02889.11 EGO57867.1 - 1.8e-47 162.1 0.0 5.6e-46 157.1 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EGO57867.1 - 8e-17 60.7 0.7 1.9e-16 59.5 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.1 EGO57868.1 - 2.9e-51 170.9 13.5 3.1e-20 71.5 2.1 5.0 3 2 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 EGO57868.1 - 1.9e-47 156.9 10.0 1.6e-10 40.1 0.1 7.1 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 EGO57868.1 - 1.5e-41 137.0 15.0 8.1e-07 28.5 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 EGO57868.1 - 3e-30 104.2 8.3 9.9e-09 35.6 0.1 6.0 4 2 1 5 5 5 4 Tetratricopeptide repeat DnaJ PF00226.26 EGO57868.1 - 4.4e-28 96.7 3.0 1.2e-27 95.4 2.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.1 EGO57868.1 - 2.5e-24 85.3 15.1 1.2e-09 38.3 0.0 5.5 4 2 2 6 6 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGO57868.1 - 4e-23 79.8 12.3 5.5e-05 23.4 0.0 8.6 4 3 4 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 EGO57868.1 - 5.4e-22 76.1 11.7 2.4e-05 24.1 0.0 7.4 7 0 0 7 7 6 5 Tetratricopeptide repeat Apc3 PF12895.2 EGO57868.1 - 1.1e-19 70.2 2.3 7.9e-10 38.7 0.1 3.6 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EGO57868.1 - 1.9e-19 67.9 11.0 0.00018 21.0 0.1 7.5 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGO57868.1 - 4.8e-19 68.0 11.3 3e-06 27.0 0.2 5.4 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 EGO57868.1 - 5.1e-19 66.5 2.7 0.021 14.6 0.0 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.1 EGO57868.1 - 1.9e-13 50.0 5.6 0.00044 20.0 0.1 5.4 3 3 1 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.1 EGO57868.1 - 2.3e-09 37.0 13.9 0.42 11.1 0.0 7.4 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_15 PF13429.1 EGO57868.1 - 1.8e-08 33.8 7.1 0.0076 15.3 0.2 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 EGO57868.1 - 8.5e-05 22.6 0.5 6.9 7.4 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 EGO57868.1 - 9.3e-05 22.4 3.8 1.2 9.3 0.0 4.5 2 2 1 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.12 EGO57868.1 - 0.00016 22.0 6.5 0.47 10.7 0.0 4.8 4 1 0 4 4 4 1 Bacterial transcriptional activator domain TPR_10 PF13374.1 EGO57868.1 - 0.0009 19.1 8.3 26 4.9 0.4 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat NYD-SP12_N PF15015.1 EGO57868.1 - 0.0035 15.6 0.1 0.057 11.6 0.0 2.1 2 0 0 2 2 2 1 Spermatogenesis-associated, N-terminal Rapsyn_N PF10579.4 EGO57868.1 - 0.007 16.1 0.2 4.2 7.2 0.0 3.5 3 1 0 3 3 3 1 Rapsyn N-terminal myristoylation and linker region NatB_MDM20 PF09797.4 EGO57868.1 - 0.026 13.2 0.0 0.054 12.1 0.0 1.5 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit SHNi-TPR PF10516.4 EGO57868.1 - 0.027 13.6 2.8 30 3.9 0.0 4.4 5 0 0 5 5 4 0 SHNi-TPR RRM_3 PF08777.6 EGO57868.1 - 0.048 13.5 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 RNA binding motif DUF3856 PF12968.2 EGO57868.1 - 0.11 12.3 1.9 43 3.9 0.0 4.7 4 2 1 5 5 5 0 Domain of Unknown Function (DUF3856) MIT PF04212.13 EGO57868.1 - 0.12 12.3 5.2 7.6 6.4 0.1 4.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 EGO57868.1 - 0.46 10.4 19.0 2.4 8.1 0.0 5.3 7 0 0 7 7 5 0 Fis1 C-terminal tetratricopeptide repeat DUF3366 PF11846.3 EGO57868.1 - 3.8 7.3 5.9 9.3 6.0 2.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3366) EF-hand_6 PF13405.1 EGO57869.1 - 5.9e-12 44.4 0.3 6.7e-06 25.5 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EGO57869.1 - 1.9e-07 29.8 2.6 0.00024 20.1 0.1 2.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EGO57869.1 - 2.4e-07 30.7 2.7 4.7e-05 23.4 0.2 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EGO57869.1 - 3.4e-06 26.1 2.9 0.00021 20.4 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 EGO57869.1 - 0.00073 19.4 0.0 0.83 9.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EGO57869.1 - 0.0036 16.8 0.2 0.98 9.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair Afi1 PF07792.7 EGO57870.1 - 8.5e-65 217.1 0.0 1.5e-64 216.4 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EGO57870.1 - 1.4e-36 124.6 0.0 2.6e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EGO57870.1 - 4e-08 32.1 0.0 0.01 14.3 0.0 3.7 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 EGO57870.1 - 0.095 11.9 0.0 0.72 9.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) BTV_NS2 PF04514.7 EGO57870.1 - 1.6 7.5 5.3 2.5 6.8 3.7 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Esterase PF00756.15 EGO57871.1 - 1e-54 185.6 0.0 1.2e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EGO57871.1 - 1.4e-06 28.0 0.0 2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO57871.1 - 1.2e-05 24.7 0.3 1.8e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGO57871.1 - 0.00044 20.2 0.0 0.00052 19.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EGO57871.1 - 0.0096 15.1 0.0 0.093 11.9 0.0 2.0 2 0 0 2 2 2 1 Esterase PHB depolymerase Chlorophyllase2 PF12740.2 EGO57871.1 - 0.017 13.9 0.0 0.039 12.8 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 EGO57871.1 - 0.043 13.3 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EGO57871.1 - 0.056 12.8 0.3 4.3 6.6 0.0 2.3 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Phg_2220_C PF09524.5 EGO57871.1 - 0.093 12.7 0.4 0.45 10.5 0.0 2.3 3 0 0 3 3 3 0 Conserved phage C-terminus (Phg_2220_C) PGAP1 PF07819.8 EGO57871.1 - 0.11 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 EGO57871.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) GARS_A PF01071.14 EGO57875.1 - 1e-52 178.5 0.0 1.7e-52 177.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.17 EGO57875.1 - 1.2e-33 116.2 0.1 2.3e-33 115.3 0.1 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EGO57875.1 - 3e-27 94.6 0.1 1.2e-26 92.7 0.0 2.0 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EGO57875.1 - 7e-16 58.2 1.2 2.4e-15 56.5 0.8 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EGO57875.1 - 0.0086 15.8 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain KTI12 PF08433.5 EGO57876.1 - 2.5e-63 213.8 0.0 4.1e-63 213.1 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EGO57876.1 - 3.6e-05 23.6 0.0 9.3e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO57876.1 - 0.013 16.2 0.0 0.033 15.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Vfa1 PF08432.5 EGO57876.1 - 0.037 14.0 2.5 0.075 13.0 1.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AAA_14 PF13173.1 EGO57876.1 - 0.047 13.5 0.0 0.2 11.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGO57876.1 - 0.06 13.4 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Dicty_REP PF05086.7 EGO57876.1 - 0.25 9.0 3.5 0.31 8.7 2.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Zn_clus PF00172.13 EGO57877.1 - 1.9e-07 30.8 11.5 4.8e-07 29.5 8.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGO57877.1 - 4.1e-06 25.6 0.0 0.013 14.1 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Pro_isomerase PF00160.16 EGO57878.1 - 6.5e-42 143.3 0.0 1.2e-41 142.5 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 EGO57878.1 - 9.3e-06 25.5 0.0 3e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 U-box domain Lung_7-TM_R PF06814.8 EGO57879.1 - 4.1e-70 236.0 15.2 5.4e-70 235.6 10.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF4131 PF13567.1 EGO57879.1 - 0.0091 15.4 1.9 0.0091 15.4 1.3 3.1 1 1 2 3 3 3 1 Domain of unknown function (DUF4131) PrgI PF12666.2 EGO57879.1 - 4 7.6 20.0 11 6.2 2.9 3.6 2 1 0 3 3 3 0 PrgI family protein DUF1673 PF07895.6 EGO57879.1 - 9.3 5.7 10.5 1.1 8.7 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Methyltransf_28 PF02636.12 EGO57880.1 - 3.4e-84 282.1 0.0 1.2e-83 280.3 0.0 1.8 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ndc1_Nup PF09531.5 EGO57880.1 - 3.7 5.8 6.8 5.2 5.3 4.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3446 PF11928.3 EGO57880.1 - 6.5 7.0 24.0 9 6.5 10.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) SR-25 PF10500.4 EGO57880.1 - 9 5.6 24.3 16 4.8 16.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Use1 PF09753.4 EGO57881.1 - 1.5e-06 27.8 6.0 6.6e-06 25.7 4.2 2.0 1 1 0 1 1 1 1 Membrane fusion protein Use1 GldM_N PF12081.3 EGO57881.1 - 0.008 15.7 0.6 0.008 15.7 0.4 1.8 2 0 0 2 2 2 1 GldM N-terminal domain Snapin_Pallidin PF14712.1 EGO57881.1 - 0.031 14.6 3.0 0.045 14.0 0.1 2.5 2 1 0 2 2 2 0 Snapin/Pallidin Vps53_N PF04100.7 EGO57881.1 - 0.14 10.9 4.8 0.13 11.0 0.2 2.1 2 0 0 2 2 2 0 Vps53-like, N-terminal DUF3347 PF11827.3 EGO57881.1 - 3.4 7.6 11.2 8.2 6.3 3.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3347) Totivirus_coat PF05518.6 EGO57881.1 - 3.6 5.2 7.2 5.1 4.7 5.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein PTCB-BRCT PF12738.2 EGO57882.1 - 0.00056 19.7 0.1 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EGO57882.1 - 0.00095 19.2 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF908 PF06012.7 EGO57882.1 - 0.07 12.4 0.6 1.2 8.3 0.0 2.0 1 1 1 2 2 2 0 Domain of Unknown Function (DUF908) Zeta_toxin PF06414.7 EGO57883.1 - 2e-55 187.0 0.0 2.6e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EGO57883.1 - 0.00067 19.5 0.0 0.0022 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EGO57883.1 - 0.041 13.3 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 EGO57883.1 - 0.042 13.8 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain PEP_mutase PF13714.1 EGO57884.1 - 1.5e-53 181.4 0.3 1.8e-53 181.1 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EGO57884.1 - 1.5e-21 76.2 0.7 2.3e-21 75.6 0.5 1.2 1 0 0 1 1 1 1 Isocitrate lyase family MTHFR PF02219.12 EGO57884.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase DUF3543 PF12063.3 EGO57885.1 - 1.1e-90 302.9 1.6 1.9e-90 302.2 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EGO57885.1 - 1.8e-62 210.8 0.0 2.8e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57885.1 - 3.8e-42 144.1 0.0 7.2e-42 143.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO57885.1 - 0.1 11.5 0.0 0.66 8.8 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.6 EGO57885.1 - 0.28 9.9 0.0 0.44 9.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glyco_transf_22 PF03901.12 EGO57889.1 - 1.3e-74 251.7 24.8 1.5e-74 251.4 17.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family LigD_N PF13298.1 EGO57889.1 - 0.013 15.6 0.1 0.023 14.8 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) Aminotran_3 PF00202.16 EGO57890.1 - 6.9e-107 357.2 0.0 8.4e-107 356.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EGO57890.1 - 1.1e-05 24.6 0.0 2.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EGO57890.1 - 0.0019 17.2 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.11 EGO57891.1 - 1.7e-36 125.6 28.4 1.7e-36 125.6 19.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF872 PF05915.7 EGO57891.1 - 3.5 7.4 5.9 7.6 6.4 0.0 3.6 2 1 2 4 4 4 0 Eukaryotic protein of unknown function (DUF872) DUF4231 PF14015.1 EGO57891.1 - 6.9 6.6 9.6 1.4 8.9 0.1 3.4 2 1 1 4 4 4 0 Protein of unknown function (DUF4231) RhoGAP PF00620.22 EGO57892.1 - 1.9e-38 131.4 0.0 3.9e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain DUF290 PF01060.18 EGO57892.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Transthyretin-like family Toxin_4 PF00706.12 EGO57893.1 - 0.05 13.8 0.3 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 Anenome neurotoxin zf-Tim10_DDP PF02953.10 EGO57894.1 - 3.8e-19 67.7 0.3 5e-19 67.3 0.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EGO57894.1 - 0.049 13.0 0.6 0.22 10.9 0.4 1.8 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) HATPase_c_5 PF14501.1 EGO57894.1 - 0.072 12.8 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 GHKL domain Nup188 PF10487.4 EGO57895.1 - 2.4e-29 101.9 1.8 8.8e-29 100.0 1.2 1.8 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.16 EGO57896.1 - 1.2e-100 335.7 0.0 2.3e-100 334.8 0.0 1.5 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EGO57896.1 - 6.6e-56 188.9 0.8 8.5e-53 178.8 0.2 2.7 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EGO57896.1 - 6.8e-51 172.4 0.0 1.1e-50 171.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGO57896.1 - 0.00015 21.2 1.5 0.0006 19.3 0.2 2.4 2 1 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.14 EGO57896.1 - 0.0021 17.6 0.9 0.033 13.7 0.0 3.1 4 0 0 4 4 4 1 Quinolinate phosphoribosyl transferase, C-terminal domain Mito_fiss_reg PF05308.6 EGO57897.1 - 1.3 8.3 13.3 0.068 12.5 5.0 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF605 PF04652.11 EGO57897.1 - 10 5.4 26.8 0.006 16.0 7.2 2.4 2 1 0 2 2 2 0 Vta1 like DUF1900 PF08954.6 EGO57898.1 - 2.1e-49 166.5 0.0 1.9e-48 163.4 0.0 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EGO57898.1 - 5.6e-30 102.7 0.0 1e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EGO57898.1 - 9.5e-25 85.5 4.9 4.8e-07 29.4 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 EGO57898.1 - 0.00037 20.2 0.0 0.002 17.9 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGO57898.1 - 0.00072 17.8 0.3 0.018 13.1 0.1 2.3 1 1 1 2 2 2 1 Nucleoporin Nup120/160 ATG16 PF08614.6 EGO57898.1 - 0.41 10.4 2.4 0.79 9.5 1.7 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) SIR2 PF02146.12 EGO57899.1 - 2.4e-25 89.3 0.0 5.2e-25 88.1 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Peptidase_C50 PF03568.12 EGO57900.1 - 8.4e-107 357.1 0.0 1.5e-106 356.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 EGO57900.1 - 8e-08 32.1 23.4 0.00094 19.0 0.2 7.8 7 1 1 8 8 8 3 Tetratricopeptide repeat CHAT PF12770.2 EGO57900.1 - 3.6e-05 23.0 1.1 0.00037 19.7 0.0 2.9 2 1 0 2 2 2 1 CHAT domain TPR_8 PF13181.1 EGO57900.1 - 0.35 10.7 5.4 37 4.4 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGO57900.1 - 0.62 9.7 16.0 1 9.0 0.1 5.2 5 0 0 5 5 5 0 TPR repeat GMC_oxred_C PF05199.8 EGO57901.1 - 8e-30 104.0 0.6 1.8e-29 102.8 0.4 1.7 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EGO57901.1 - 8.2e-25 87.5 0.1 1.9e-24 86.3 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.13 EGO57901.1 - 2.5e-10 39.8 12.8 6.7e-10 38.4 8.9 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.19 EGO57901.1 - 1.2e-08 34.1 1.3 0.0019 17.0 0.5 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGO57901.1 - 3e-06 26.3 3.2 4.9e-05 22.3 2.2 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO57901.1 - 0.00018 21.6 0.0 0.0081 16.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO57901.1 - 0.00033 19.8 0.0 0.15 11.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO57901.1 - 0.00099 19.0 0.0 0.004 17.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DOMON PF03351.12 EGO57901.1 - 0.0012 18.7 0.1 0.004 17.0 0.0 1.9 1 1 0 1 1 1 1 DOMON domain NAD_binding_8 PF13450.1 EGO57901.1 - 0.0032 17.4 0.0 0.0086 16.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGO57901.1 - 0.0032 16.0 0.1 0.0068 14.9 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EGO57901.1 - 0.054 12.5 0.6 0.19 10.7 0.2 1.9 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 EGO57901.1 - 0.089 13.2 0.6 0.43 11.0 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO57901.1 - 0.1 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EGO57901.1 - 0.26 10.0 0.4 0.98 8.2 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A 2OG-FeII_Oxy_3 PF13640.1 EGO57902.1 - 0.0013 19.2 0.2 0.004 17.6 0.1 1.9 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EGO57902.1 - 0.0087 15.6 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FliT PF05400.8 EGO57904.1 - 0.078 13.3 0.4 0.078 13.3 0.3 2.9 3 0 0 3 3 3 0 Flagellar protein FliT DUF1664 PF07889.7 EGO57904.1 - 0.14 11.9 3.6 0.18 11.6 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RRM_5 PF13893.1 EGO57905.1 - 7.3e-09 35.3 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO57905.1 - 1.1e-08 34.5 0.0 2.2e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO57905.1 - 1.3e-07 31.4 0.0 2.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sedlin_N PF04628.8 EGO57907.1 - 7.1e-45 152.1 0.0 8.1e-45 151.9 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EGO57907.1 - 4.1e-05 23.3 0.2 0.0038 16.9 0.0 2.2 1 1 1 2 2 2 2 Sybindin-like family Cytochrome-c551 PF10643.4 EGO57907.1 - 0.13 11.5 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Histone PF00125.19 EGO57909.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EGO57909.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EGO57909.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGO57909.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGO57909.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EGO57909.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TPR_11 PF13414.1 EGO57910.1 - 1.2e-37 127.3 31.5 5.8e-13 48.2 4.5 7.4 5 2 2 7 7 7 6 TPR repeat TPR_1 PF00515.23 EGO57910.1 - 1.5e-34 116.1 20.3 3.8e-06 26.2 0.3 8.9 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 EGO57910.1 - 1.4e-32 108.9 34.8 1.7e-05 24.3 0.2 10.3 11 0 0 11 11 11 7 Tetratricopeptide repeat Apc3 PF12895.2 EGO57910.1 - 7.6e-30 102.8 28.6 9e-20 70.6 0.8 5.0 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGO57910.1 - 6.3e-29 99.7 26.3 8e-06 25.7 0.0 7.9 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 EGO57910.1 - 4.7e-26 88.5 10.6 2.8e-05 23.5 1.2 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGO57910.1 - 4.3e-22 78.2 20.7 1.3e-10 41.4 1.6 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGO57910.1 - 3.2e-21 73.8 21.0 0.042 14.4 0.1 9.6 5 1 4 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 EGO57910.1 - 2.6e-20 72.5 31.1 2.4e-08 34.4 1.4 8.0 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 EGO57910.1 - 5.6e-19 66.3 13.8 0.001 18.6 0.0 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 EGO57910.1 - 9.9e-19 65.9 16.8 0.001 19.1 0.4 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_6 PF13174.1 EGO57910.1 - 1.4e-10 40.8 21.2 0.022 15.2 0.0 9.1 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGO57910.1 - 7.9e-07 28.8 10.6 0.0017 18.1 0.3 5.2 4 2 2 6 6 6 2 Tetratricopeptide repeat DUF2225 PF09986.4 EGO57910.1 - 0.005 16.3 2.2 0.63 9.4 0.6 3.1 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 EGO57910.1 - 0.0085 15.9 3.6 0.78 9.6 0.1 4.2 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EGO57910.1 - 0.035 14.0 11.4 1.7 8.6 0.0 5.8 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGO57910.1 - 0.14 12.6 10.4 24 5.7 0.2 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat NARP1 PF12569.3 EGO57910.1 - 7.9 5.1 15.2 1.6 7.3 0.0 3.4 5 0 0 5 5 4 0 NMDA receptor-regulated protein 1 bZIP_1 PF00170.16 EGO57911.1 - 0.0015 18.4 3.4 0.0046 16.8 2.3 1.8 1 0 0 1 1 1 1 bZIP transcription factor NYD-SP28_assoc PF14775.1 EGO57911.1 - 0.014 15.0 4.1 0.016 14.8 1.9 1.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain DivIC PF04977.10 EGO57911.1 - 0.065 12.7 2.1 0.13 11.7 1.5 1.5 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.10 EGO57911.1 - 0.16 11.7 11.6 0.017 14.9 3.3 2.7 2 1 0 2 2 2 0 Basic region leucine zipper TSC22 PF01166.13 EGO57911.1 - 0.33 10.9 4.8 0.11 12.5 1.1 1.8 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4407 PF14362.1 EGO57911.1 - 9.8 5.0 7.9 19 4.1 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSP70 PF00012.15 EGO57912.1 - 9.7e-07 27.0 0.0 8.7e-06 23.9 0.0 2.1 1 1 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.11 EGO57912.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain MreB_Mbl PF06723.8 EGO57912.1 - 0.028 13.0 0.0 0.065 11.8 0.0 1.5 2 0 0 2 2 2 0 MreB/Mbl protein MMR_HSR1 PF01926.18 EGO57913.1 - 2.9e-10 40.0 0.0 7.3e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 EGO57913.1 - 2.5e-09 36.5 0.0 4.4e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Septin PF00735.13 EGO57913.1 - 3.7e-07 29.4 0.1 7.5e-07 28.4 0.0 1.5 2 0 0 2 2 2 1 Septin Dynamin_N PF00350.18 EGO57913.1 - 5.3e-07 29.5 2.7 0.015 15.1 0.1 2.5 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EGO57913.1 - 1.7e-05 24.0 0.2 4.7e-05 22.6 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EGO57913.1 - 0.00028 20.1 0.2 0.00057 19.1 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EGO57913.1 - 0.0013 19.2 0.0 0.0038 17.7 0.0 1.8 2 0 0 2 2 1 1 Miro-like protein AAA_29 PF13555.1 EGO57913.1 - 0.0017 17.8 1.1 0.0035 16.8 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EGO57913.1 - 0.0019 18.2 0.1 0.0091 15.9 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGO57913.1 - 0.0019 18.3 0.4 0.016 15.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EGO57913.1 - 0.0022 18.2 0.1 0.0064 16.8 0.0 1.9 2 1 0 2 2 2 1 ABC transporter T2SE PF00437.15 EGO57913.1 - 0.0031 16.4 1.0 0.011 14.6 0.2 2.0 1 1 1 2 2 2 1 Type II/IV secretion system protein IIGP PF05049.8 EGO57913.1 - 0.0067 15.2 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 EGO57913.1 - 0.012 15.1 0.1 0.012 15.1 0.1 2.0 2 1 0 2 2 2 0 FtsK/SpoIIIE family Cob_adeno_trans PF01923.13 EGO57913.1 - 0.012 15.3 0.1 0.02 14.7 0.1 1.4 1 0 0 1 1 1 0 Cobalamin adenosyltransferase AAA_17 PF13207.1 EGO57913.1 - 0.019 15.8 0.5 0.057 14.2 0.4 2.1 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGO57913.1 - 0.025 14.9 0.6 0.033 14.5 0.4 1.7 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 EGO57913.1 - 0.047 12.9 0.0 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO57913.1 - 0.048 12.7 0.0 0.095 11.8 0.0 1.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 EGO57913.1 - 0.053 13.3 0.3 0.053 13.3 0.2 1.8 2 1 0 2 2 1 0 AAA domain PduV-EutP PF10662.4 EGO57913.1 - 0.058 12.8 0.3 0.45 9.9 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_P4 PF11602.3 EGO57913.1 - 0.08 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 GTP_EFTU PF00009.22 EGO57913.1 - 0.081 12.3 0.2 0.6 9.5 0.1 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EGO57913.1 - 0.096 12.2 0.9 0.47 9.9 0.3 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Ndc80_HEC PF03801.8 EGO57913.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 HEC/Ndc80p family DUF87 PF01935.12 EGO57913.1 - 0.16 11.7 1.9 0.26 11.1 0.2 2.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EGO57913.1 - 0.72 9.2 2.9 2.6 7.3 2.0 2.2 1 1 0 1 1 1 0 AAA-like domain DUF788 PF05620.6 EGO57914.1 - 9.7e-47 158.9 0.0 1.1e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) DUF2955 PF11168.3 EGO57914.1 - 0.023 14.3 0.2 0.23 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) FA_desaturase PF00487.19 EGO57914.1 - 0.42 10.0 4.2 0.57 9.5 2.9 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF3605 PF12239.3 EGO57915.1 - 2e-58 196.7 0.0 2.7e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FAD_binding_6 PF00970.19 EGO57916.1 - 1.6e-27 95.5 0.0 2.3e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGO57916.1 - 2.6e-27 95.5 0.0 4e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EGO57916.1 - 0.00048 20.0 0.0 0.066 13.1 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EGO57916.1 - 0.018 14.9 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Fungal_trans PF04082.13 EGO57917.1 - 1.7e-07 30.3 0.1 5.4e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO57917.1 - 2.9e-05 23.8 5.2 2.9e-05 23.8 3.6 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.19 EGO57917.1 - 0.00069 19.6 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.1 EGO57917.1 - 0.024 14.3 0.0 0.065 12.9 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_3 PF13302.1 EGO57917.1 - 0.038 14.1 0.6 0.32 11.1 0.0 2.6 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO57917.1 - 0.075 13.1 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arf PF00025.16 EGO57918.1 - 3.1e-69 231.6 1.2 3.5e-69 231.5 0.8 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGO57918.1 - 4.1e-13 49.0 0.0 4.8e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EGO57918.1 - 3.6e-12 45.6 1.8 3.1e-07 29.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGO57918.1 - 6.3e-10 38.5 0.0 7.4e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGO57918.1 - 1.5e-09 38.3 0.0 2.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGO57918.1 - 3e-09 36.8 0.0 4.1e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGO57918.1 - 4.2e-08 32.6 0.0 4.9e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EGO57918.1 - 1.3e-06 27.9 0.0 0.00011 21.6 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.7 EGO57918.1 - 0.0026 17.4 0.1 0.082 12.5 0.0 2.1 2 0 0 2 2 2 1 NACHT domain ArgK PF03308.11 EGO57918.1 - 0.0033 16.2 0.1 0.021 13.6 0.0 1.9 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 EGO57918.1 - 0.0055 17.5 0.3 0.0085 16.8 0.2 1.5 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EGO57918.1 - 0.05 13.0 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.13 EGO57918.1 - 0.062 12.3 0.1 0.13 11.3 0.1 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase FeoB_N PF02421.13 EGO57918.1 - 0.075 12.3 0.3 0.21 10.8 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_33 PF13671.1 EGO57918.1 - 0.11 12.3 0.0 0.35 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF4045 PF13254.1 EGO57919.1 - 1.8e-75 254.8 31.1 4.7e-48 164.5 15.2 7.5 4 3 4 8 8 8 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 EGO57919.1 - 1.3e-11 44.0 0.0 0.001 18.6 0.0 3.8 3 0 0 3 3 3 3 Gelsolin repeat DUF3894 PF13033.1 EGO57919.1 - 0.54 10.2 0.2 0.95 9.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3894) Med10 PF09748.4 EGO57920.1 - 3e-51 172.5 0.0 4e-51 172.1 0.0 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF2763 PF10961.3 EGO57920.1 - 0.36 11.2 3.4 17 5.8 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2763) bZIP_1 PF00170.16 EGO57923.1 - 3.8e-05 23.5 7.4 3.8e-05 23.5 5.1 2.0 2 0 0 2 2 2 1 bZIP transcription factor TMF_TATA_bd PF12325.3 EGO57923.1 - 0.043 13.5 1.8 4.4 7.0 1.8 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.10 EGO57923.1 - 2.8 7.8 10.9 1.5 8.7 5.2 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF4407 PF14362.1 EGO57923.1 - 4.6 6.1 8.5 5.9 5.7 5.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Stm1_N PF09598.5 EGO57925.1 - 2.3e-16 60.2 0.9 2.3e-16 60.2 0.6 5.1 4 2 0 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.10 EGO57925.1 - 8.7e-11 42.2 10.2 8.7e-11 42.2 7.1 2.9 3 0 0 3 3 3 1 Hyaluronan / mRNA binding family MFS_1 PF07690.11 EGO57926.1 - 7.5e-17 61.0 31.6 3.7e-10 39.0 5.8 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EGO57926.1 - 1.7e-07 29.9 11.1 9.1e-06 24.3 2.7 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 EGO57926.1 - 0.0068 16.1 4.8 0.16 11.7 0.0 4.1 4 0 0 4 4 4 1 MFS_1 like family Mtc PF03820.12 EGO57927.1 - 4.1e-104 347.5 0.1 2.7e-103 344.8 0.1 1.8 1 1 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.20 EGO57930.1 - 7.4e-31 107.2 0.0 1.1e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO57930.1 - 3.5e-14 52.5 0.0 5.9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Lactamase_B_2 PF12706.2 EGO57933.1 - 8.8e-33 113.4 0.0 2.4e-32 112.0 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EGO57933.1 - 2.6e-23 81.2 0.0 8.5e-23 79.6 0.0 2.0 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EGO57933.1 - 4.1e-12 46.1 0.1 1.9e-11 43.9 0.1 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_hydro_16 PF00722.16 EGO57934.1 - 2.3e-07 30.2 0.5 2.3e-07 30.2 0.4 1.7 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Polysacc_lyase PF14099.1 EGO57934.1 - 0.16 11.6 3.1 0.44 10.1 2.1 1.7 1 1 0 1 1 1 0 Polysaccharide lyase DUF997 PF06196.7 EGO57935.1 - 0.18 11.3 0.0 0.38 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF997) DEAD PF00270.24 EGO57936.1 - 1.1e-43 148.6 0.9 6.1e-43 146.2 0.1 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO57936.1 - 1.7e-26 91.9 0.0 4.2e-26 90.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EGO57936.1 - 0.00054 18.4 0.1 0.00054 18.4 0.1 4.3 2 1 2 4 4 4 1 Protein of unknown function (DUF1253) DUF2183 PF09949.4 EGO57937.1 - 6.4e-33 112.6 0.0 1.4e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 EGO57937.1 - 0.0051 16.3 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Flavin_Reduct PF01613.13 EGO57938.1 - 6.9e-07 29.2 0.0 8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain PDEase_II PF02112.10 EGO57939.1 - 4.2e-56 190.2 0.0 2.1e-26 92.6 0.0 3.2 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EGO57939.1 - 0.00028 20.4 0.7 0.0047 16.5 0.5 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGO57939.1 - 0.018 14.6 1.7 0.14 11.7 1.2 2.3 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily AMP-binding PF00501.23 EGO57941.1 - 4.5e-61 206.4 0.2 3.6e-33 114.5 0.0 4.3 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.6 EGO57941.1 - 6e-11 42.9 0.0 1.6e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 EGO57941.1 - 0.0001 22.0 0.0 0.00028 20.6 0.0 1.7 1 0 0 1 1 1 1 Gas vesicle protein G PX PF00787.19 EGO57943.1 - 4.4e-15 55.4 0.0 7.1e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EGO57943.1 - 9.1e-10 38.0 4.2 1.9e-09 37.0 2.9 1.5 1 0 0 1 1 1 1 SNARE domain MitMem_reg PF13012.1 EGO57943.1 - 0.0065 16.5 0.4 0.012 15.6 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function FAM104 PF15434.1 EGO57943.1 - 2.3 8.4 5.8 0.38 10.9 0.8 2.0 2 0 0 2 2 2 0 Family 104 EB1 PF03271.12 EGO57944.1 - 4.1e-17 61.9 0.5 9.8e-17 60.7 0.3 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EGO57944.1 - 4.3e-07 29.9 0.5 6.3e-07 29.4 0.4 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Glyco_transf_8 PF01501.15 EGO57945.1 - 3.5e-26 92.0 0.0 5.3e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EGO57945.1 - 0.00058 19.2 0.0 0.00096 18.5 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Herpes_capsid PF06112.6 EGO57947.1 - 9.4 6.2 11.8 0.59 10.1 1.4 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein RCR PF12273.3 EGO57950.1 - 3.7e-07 30.7 1.1 5.9e-07 30.1 0.7 1.4 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Adeno_E3_CR2 PF02439.10 EGO57950.1 - 7e-05 22.2 2.6 0.00013 21.4 1.8 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF1183 PF06682.7 EGO57950.1 - 0.00011 21.9 0.0 0.00013 21.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Shisa PF13908.1 EGO57950.1 - 0.00056 20.1 0.0 0.00076 19.7 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator IncA PF04156.9 EGO57950.1 - 0.0094 15.5 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 1 IncA protein EphA2_TM PF14575.1 EGO57950.1 - 0.052 13.9 0.0 0.071 13.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4083 PF13314.1 EGO57950.1 - 0.075 12.8 1.1 0.11 12.3 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF2550 PF10739.4 EGO57950.1 - 0.099 12.5 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) GRA6 PF05084.8 EGO57950.1 - 0.18 11.3 0.3 0.22 11.0 0.2 1.2 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Herpes_gE PF02480.11 EGO57950.1 - 0.34 9.1 1.1 0.29 9.3 0.2 1.4 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 EGO57950.1 - 0.99 8.7 5.5 1.7 8.0 3.8 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain OSTMP1 PF09777.4 EGO57951.1 - 0.011 14.9 0.0 0.014 14.6 0.0 1.0 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor PgaD PF13994.1 EGO57951.1 - 0.052 13.0 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 PgaD-like protein Vpu PF00558.14 EGO57951.1 - 0.1 12.1 0.5 0.14 11.7 0.3 1.1 1 0 0 1 1 1 0 Vpu protein CD34_antigen PF06365.7 EGO57951.1 - 0.11 12.1 0.1 0.11 12.1 0.1 1.4 2 0 0 2 2 2 0 CD34/Podocalyxin family ASFV_J13L PF05568.6 EGO57951.1 - 0.15 11.5 4.2 0.26 10.7 2.5 1.6 1 1 0 1 1 1 0 African swine fever virus J13L protein Asp PF00026.18 EGO57952.1 - 3.8e-38 131.4 0.5 3.1e-37 128.5 0.3 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Peptidase_C2 PF00648.16 EGO57954.1 - 7.2e-53 179.5 1.1 1.1e-36 126.4 0.3 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease LRR_4 PF12799.2 EGO57955.1 - 0.063 12.9 4.8 0.48 10.0 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) EBP PF05241.7 EGO57956.1 - 1.1e-05 24.5 2.8 1.1e-05 24.5 2.0 1.5 1 1 0 1 1 1 1 Emopamil binding protein DUF1625 PF07787.7 EGO57957.1 - 7.5 5.7 6.1 4.4 6.4 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) Dynactin_p62 PF05502.8 EGO57961.1 - 9.9e-202 670.9 0.0 1.2e-201 670.7 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family DUF4519 PF15012.1 EGO57961.1 - 0.085 12.7 3.3 0.19 11.6 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Ribosomal_S7e PF01251.13 EGO57962.1 - 6.4e-83 276.9 0.5 7.1e-83 276.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ADH_N PF08240.7 EGO57964.1 - 1.8e-26 92.0 2.5 3e-26 91.3 1.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO57964.1 - 2.8e-14 52.7 0.1 7.3e-14 51.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGO57964.1 - 1.1e-05 24.6 0.1 2.1e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EGO57964.1 - 0.038 14.1 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CTP_synth_N PF06418.9 EGO57965.1 - 1.2e-106 355.9 0.1 1.7e-106 355.3 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EGO57965.1 - 6.1e-56 188.9 0.0 9.7e-56 188.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGO57965.1 - 6.7e-08 32.2 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 DUF3862 PF12978.2 EGO57965.1 - 0.1 12.2 0.1 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3862) GATase PF00117.23 EGO57966.1 - 6.6e-07 28.9 0.0 1.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EGO57966.1 - 0.053 13.1 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S8 PF00082.17 EGO57967.1 - 1.7e-41 142.2 0.0 4.5e-41 140.8 0.0 1.8 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EGO57967.1 - 5.2e-15 55.8 1.0 1.3e-14 54.5 0.2 2.1 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) PA PF02225.17 EGO57967.1 - 2e-12 46.6 1.4 5.4e-12 45.2 0.1 2.3 2 0 0 2 2 2 1 PA domain FlgD_ig PF13860.1 EGO57967.1 - 1.1e-07 31.5 0.1 3.9e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 FlgD Ig-like domain BolA PF01722.13 EGO57968.1 - 2.3e-14 53.0 0.0 3.7e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 BolA-like protein Mucin PF01456.12 EGO57968.1 - 0.01 15.6 0.5 0.013 15.2 0.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein PAT1 PF09770.4 EGO57970.1 - 3.4 5.7 11.2 3.8 5.6 7.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.8 EGO57970.1 - 4.6 5.9 11.2 6 5.6 7.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Bac_chlorC PF02043.12 EGO57970.1 - 6.8 6.5 5.6 2.3 8.0 0.1 2.1 1 1 1 2 2 2 0 Bacteriochlorophyll C binding protein LNP1 PF15419.1 EGO57972.1 - 0.51 10.4 5.2 0.28 11.2 1.2 2.2 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 SRI PF08236.6 EGO57973.1 - 9e-23 80.0 4.2 3.2e-22 78.2 2.9 2.0 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 EGO57973.1 - 2.2e-21 76.8 0.1 2.2e-21 76.8 0.1 3.6 3 2 0 3 3 3 1 SET domain WW PF00397.21 EGO57973.1 - 1.4e-05 24.7 2.3 2.9e-05 23.8 1.6 1.6 1 0 0 1 1 1 1 WW domain Med26 PF08711.6 EGO57973.1 - 0.0002 20.7 0.1 0.00051 19.4 0.1 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Nodulin_late PF07127.6 EGO57973.1 - 2.7 8.1 4.9 2.6 8.2 1.5 2.1 2 0 0 2 2 2 0 Late nodulin protein Cullin PF00888.17 EGO57974.1 - 3.1e-114 382.6 0.4 8.4e-114 381.2 0.0 1.7 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EGO57974.1 - 8.5e-27 92.7 1.1 2.4e-26 91.3 0.8 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF3414 PF11894.3 EGO57975.1 - 0 1587.1 5.5 0 1586.9 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) PI3_PI4_kinase PF00454.22 EGO57976.1 - 3.5e-45 154.3 0.0 6.9e-45 153.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EGO57976.1 - 3.4e-40 137.2 2.7 5.2e-40 136.7 0.0 2.9 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair FAT PF02259.18 EGO57976.1 - 1.9e-38 132.3 5.6 1.9e-38 132.3 3.9 2.6 3 0 0 3 3 3 1 FAT domain FATC PF02260.15 EGO57976.1 - 6.9e-11 41.3 0.4 2.4e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 FATC domain zf-C3HC4_3 PF13920.1 EGO57977.1 - 2e-11 43.3 7.6 3.5e-11 42.5 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO57977.1 - 8.7e-10 38.2 10.5 8.7e-10 38.2 7.3 1.6 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO57977.1 - 6.3e-08 32.5 9.9 6.3e-08 32.5 6.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO57977.1 - 2.2e-07 30.4 9.4 3.8e-07 29.7 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGO57977.1 - 3e-06 26.7 9.4 3e-06 26.7 6.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGO57977.1 - 0.0011 18.7 3.5 0.0021 17.8 2.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGO57977.1 - 0.0016 17.9 4.8 0.0032 17.0 3.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EGO57977.1 - 0.0068 16.2 8.5 0.015 15.1 5.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGO57977.1 - 0.0078 15.9 4.0 0.0078 15.9 2.8 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.2 EGO57977.1 - 0.054 13.6 4.7 0.11 12.5 3.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EGO57977.1 - 0.2 11.2 10.4 1.5 8.4 6.2 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 TerY-C PF15616.1 EGO57977.1 - 0.29 11.0 2.5 0.51 10.2 1.7 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_6 PF14835.1 EGO57977.1 - 0.36 10.6 4.2 0.67 9.7 2.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 EGO57977.1 - 3.2 7.3 7.7 7.9 6.0 5.3 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DNA_pol_A PF00476.15 EGO57978.1 - 7.8e-99 330.8 0.0 1.2e-98 330.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A Mad3_BUB1_I PF08311.7 EGO57978.1 - 0.012 15.4 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 DNA_pol_A_exo1 PF01612.15 EGO57978.1 - 0.04 13.3 1.3 0.6 9.5 0.9 2.3 1 1 0 1 1 1 0 3'-5' exonuclease CH PF00307.26 EGO57979.1 - 1.4e-10 41.1 0.0 2.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGO57979.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain MIP-T3 PF10243.4 EGO57979.1 - 3.7 5.8 60.8 0.029 12.8 36.7 1.4 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 NDUFA12 PF05071.11 EGO57980.1 - 4.7e-13 49.5 0.1 4.7e-13 49.5 0.1 2.8 2 1 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF4124 PF13511.1 EGO57980.1 - 0.33 11.0 0.1 0.33 11.0 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4124) Dicty_REP PF05086.7 EGO57980.1 - 3.4 5.2 6.0 4.4 4.9 4.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4554 PF15091.1 EGO57981.1 - 0.0025 16.6 0.4 0.0043 15.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4554) HTH_Tnp_4 PF13613.1 EGO57981.1 - 0.0076 15.7 0.2 0.016 14.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Vps51 PF08700.6 EGO57982.1 - 1e-16 60.5 0.0 3.9e-16 58.6 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 DDE_Tnp_ISL3 PF01610.12 EGO57982.1 - 0.061 12.9 1.4 0.07 12.6 0.1 1.7 2 0 0 2 2 2 0 Transposase Sec62 PF03839.11 EGO57982.1 - 1.1 8.5 4.9 2.6 7.4 3.4 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 Glyco_transf_28 PF03033.15 EGO57983.1 - 3.7e-17 62.3 0.0 1.1e-16 60.8 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EGO57983.1 - 3.4e-06 25.9 0.0 7.8e-06 24.7 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EGO57983.1 - 0.042 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Zn_clus PF00172.13 EGO57984.1 - 0.0053 16.6 9.8 0.0091 15.8 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.17 EGO57985.1 - 2.5 7.0 4.7 3.7 6.4 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter zf-C2H2_4 PF13894.1 EGO57987.1 - 5e-05 23.3 7.8 0.0081 16.4 0.4 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO57987.1 - 0.009 16.3 4.9 0.86 10.0 0.1 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type Ndc1_Nup PF09531.5 EGO57987.1 - 8.3 4.7 7.7 0.25 9.7 0.4 1.7 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup HeLo PF14479.1 EGO57988.1 - 5.2e-46 157.0 1.1 1.1e-45 156.0 0.8 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 EGO57988.1 - 2.8e-05 23.3 0.0 6.8e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGO57988.1 - 0.00012 21.3 0.0 0.00026 20.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Zn_clus PF00172.13 EGO57990.1 - 9.7e-09 34.9 4.8 2e-08 33.9 3.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGO57990.1 - 6.4e-08 31.7 0.0 2e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain COesterase PF00135.23 EGO57991.1 - 1.6e-80 271.3 0.0 6.3e-80 269.3 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO57991.1 - 3e-12 46.5 0.1 7.1e-12 45.3 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO57991.1 - 0.0011 18.2 0.5 0.0019 17.4 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO57991.1 - 0.0052 16.5 0.2 0.009 15.7 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family NUDIX-like PF09296.6 EGO57992.1 - 4.8e-25 87.7 0.3 3.5e-24 84.9 0.1 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.23 EGO57992.1 - 1.9e-18 66.3 0.1 3.3e-17 62.3 0.0 2.3 2 0 0 2 2 2 1 NUDIX domain zf-NADH-PPase PF09297.6 EGO57992.1 - 1.7e-09 36.9 1.8 3.1e-09 36.1 1.2 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Ribosomal_L1 PF00687.16 EGO57993.1 - 1.2e-52 178.4 0.3 1.4e-52 178.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Kinetochor_Ybp2 PF08568.5 EGO57994.1 - 9.3e-152 506.4 0.0 1.1e-151 506.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin NPCBM_assoc PF10633.4 EGO57995.1 - 0.033 14.2 0.0 0.036 14.0 0.0 1.1 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase SET PF00856.23 EGO57996.1 - 8.4e-11 42.4 0.0 2.1e-10 41.1 0.0 1.7 2 0 0 2 2 2 1 SET domain MFS_1 PF07690.11 EGO58000.1 - 7.2e-21 74.2 34.6 7.2e-21 74.2 24.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EGO58000.1 - 2.5e-08 32.7 7.6 2.5e-08 32.7 5.3 2.7 1 1 2 3 3 3 2 MFS/sugar transport protein Peptidase_M56 PF05569.6 EGO58000.1 - 0.2 10.5 0.0 0.44 9.4 0.0 1.5 1 0 0 1 1 1 0 BlaR1 peptidase M56 E1-E2_ATPase PF00122.15 EGO58000.1 - 2.7 6.9 4.1 2 7.3 0.0 2.3 2 1 0 2 2 2 0 E1-E2 ATPase ECH PF00378.15 EGO58001.1 - 5.1e-21 74.9 0.0 1.5e-20 73.3 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PQ-loop PF04193.9 EGO58002.1 - 1.1e-39 133.7 12.1 1.6e-20 72.4 1.8 2.6 2 0 0 2 2 2 2 PQ loop repeat Sas10 PF09368.5 EGO58003.1 - 3.2e-30 104.1 8.8 3.2e-30 104.1 6.1 3.1 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EGO58003.1 - 3.7e-12 46.2 2.2 1.9e-11 44.0 0.0 3.1 2 1 0 2 2 2 1 Sas10/Utp3/C1D family adh_short PF00106.20 EGO58004.1 - 1.1e-17 64.4 0.2 1.4e-17 64.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO58004.1 - 3.8e-06 26.7 0.1 6.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EGO58004.1 - 0.00012 21.7 0.1 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 EGO58004.1 - 0.0036 17.1 0.0 0.0049 16.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGO58004.1 - 0.017 15.1 4.5 0.13 12.2 1.9 2.7 2 1 0 2 2 2 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EGO58004.1 - 0.044 12.8 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3716 PF12511.3 EGO58005.1 - 1.4e-16 59.8 8.3 2.3e-16 59.1 5.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Macoilin PF09726.4 EGO58005.1 - 0.18 10.0 4.0 0.22 9.7 2.7 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF1771 PF08590.5 EGO58006.1 - 1.7e-22 79.1 10.4 1.7e-22 79.1 7.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EGO58006.1 - 1.5e-16 60.3 0.2 1.5e-16 60.3 0.1 2.0 2 0 0 2 2 2 1 Smr domain Methyltransf_23 PF13489.1 EGO58007.1 - 2.4e-15 56.6 0.0 3.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO58007.1 - 2.2e-11 44.0 0.0 5e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO58007.1 - 1.7e-09 37.3 0.0 3.8e-08 33.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO58007.1 - 5.7e-09 36.3 0.0 4.2e-08 33.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO58007.1 - 6.6e-08 33.1 0.0 1e-06 29.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO58007.1 - 1.1e-05 24.7 0.0 7e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGO58007.1 - 0.0015 18.8 0.0 0.0054 17.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO58007.1 - 0.0016 17.5 0.0 0.0029 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EGO58007.1 - 0.0059 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EGO58007.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase GidB PF02527.10 EGO58007.1 - 0.05 12.7 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_26 PF13659.1 EGO58007.1 - 0.091 12.7 0.0 1 9.3 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EGO58007.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase PrmA PF06325.8 EGO58007.1 - 0.16 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) adh_short PF00106.20 EGO58008.1 - 1.3e-15 57.7 0.0 2.5e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO58008.1 - 3.1e-05 23.8 0.1 3.9e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EGO58008.1 - 0.05 12.7 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EGO58008.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding KR PF08659.5 EGO58008.1 - 0.072 12.7 0.0 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 KR domain Eno-Rase_NADH_b PF12242.3 EGO58008.1 - 0.08 12.7 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AP3B1_C PF14796.1 EGO58008.1 - 0.14 11.8 0.5 0.64 9.7 0.3 2.0 1 1 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal MFS_1 PF07690.11 EGO58009.1 - 3.2e-35 121.4 43.1 3.2e-35 121.4 29.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Nol1_Nop2_Fmu PF01189.12 EGO58011.1 - 1.7e-21 76.8 0.0 1.2e-16 60.9 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family DUF1996 PF09362.5 EGO58012.1 - 6.2e-66 222.4 0.1 9.9e-66 221.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EGO58012.1 - 3e-18 65.4 12.2 4e-18 65.1 6.7 2.3 2 0 0 2 2 2 1 WSC domain Defensin_2 PF01097.13 EGO58012.1 - 0.046 13.4 4.9 0.12 12.0 1.0 2.6 2 0 0 2 2 2 0 Arthropod defensin TPR_11 PF13414.1 EGO58013.1 - 8.7e-26 89.3 21.3 5.3e-07 29.2 0.0 7.9 7 1 1 8 8 8 5 TPR repeat TPR_16 PF13432.1 EGO58013.1 - 1.9e-15 57.0 29.0 5.9e-05 23.6 0.1 8.1 8 2 2 10 10 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGO58013.1 - 1.5e-13 50.8 19.3 0.0039 17.5 0.3 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGO58013.1 - 1.3e-12 47.1 22.2 0.04 14.5 0.1 10.5 9 2 2 11 11 11 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGO58013.1 - 1e-11 44.6 22.9 8.2e-07 28.8 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGO58013.1 - 4.9e-10 38.5 11.5 0.079 12.5 0.0 9.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGO58013.1 - 1.5e-09 36.9 13.3 0.11 12.3 0.0 8.3 8 2 2 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGO58013.1 - 5.3e-09 35.5 12.3 0.1 12.8 0.1 8.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGO58013.1 - 3.2e-07 29.7 26.6 0.38 10.7 0.1 10.1 13 0 0 13 13 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGO58013.1 - 0.00075 19.1 11.4 0.32 10.9 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EGO58013.1 - 0.00076 19.7 7.5 0.33 11.1 0.0 4.1 4 0 0 4 4 4 2 Alkyl sulfatase dimerisation Apc3 PF12895.2 EGO58013.1 - 0.00095 19.2 13.5 1.2 9.3 0.2 6.1 5 1 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 EGO58013.1 - 0.0074 16.3 11.1 0.59 10.2 1.7 4.4 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGO58013.1 - 0.17 11.7 13.0 1 9.2 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGO58013.1 - 8.4 7.1 14.3 1.5e+02 3.1 0.0 6.8 6 1 0 6 6 4 0 Tetratricopeptide repeat SAM_2 PF07647.12 EGO58014.1 - 1.1e-10 41.1 0.2 2.1e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGO58014.1 - 4.8e-06 26.6 0.3 1.2e-05 25.3 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 EGO58014.1 - 0.04 13.8 0.3 0.096 12.6 0.2 1.6 1 0 0 1 1 1 0 IGR protein motif MerR PF00376.18 EGO58017.1 - 0.72 9.4 2.9 6.7 6.3 0.0 2.3 2 0 0 2 2 2 0 MerR family regulatory protein CRT10 PF08728.5 EGO58018.1 - 0.21 9.5 0.3 0.28 9.1 0.2 1.1 1 0 0 1 1 1 0 CRT10 Ribosomal_L29e PF01779.12 EGO58020.1 - 3.5e-23 81.1 9.2 6.1e-23 80.3 6.4 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family Mito_carr PF00153.22 EGO58021.1 - 2e-57 190.8 3.0 3.9e-19 68.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AP2 PF00847.15 EGO58022.1 - 0.04 14.0 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 AP2 domain Peptidase_C2 PF00648.16 EGO58023.1 - 2e-28 99.2 0.0 3.3e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EGO58023.1 - 4.8e-19 68.4 0.0 1.6e-17 63.5 0.0 2.5 2 1 0 2 2 2 1 Calpain large subunit, domain III MIT PF04212.13 EGO58023.1 - 0.15 12.0 0.8 0.23 11.3 0.6 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain MA-Mit PF09245.5 EGO58025.1 - 0.15 11.3 0.4 0.26 10.5 0.3 1.3 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen DUF607 PF04678.8 EGO58025.1 - 0.33 10.8 3.4 0.59 10.0 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF607 RNase_P_pop3 PF08228.6 EGO58026.1 - 3.5e-08 33.4 0.0 5.3e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 RNase P subunit Pop3 UCH PF00443.24 EGO58027.1 - 6.4e-45 153.3 3.2 8.5e-45 152.9 1.6 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 EGO58027.1 - 1.3e-22 79.8 0.0 2.3e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 EGO58027.1 - 1.1e-19 71.0 0.3 2.3e-19 69.9 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ACT_6 PF13740.1 EGO58029.1 - 0.0099 15.5 1.3 0.024 14.3 0.1 2.2 2 0 0 2 2 2 1 ACT domain Baculo_PEP_C PF04513.7 EGO58029.1 - 0.02 14.7 9.3 0.064 13.0 6.5 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.6 EGO58029.1 - 0.097 10.1 1.4 0.13 9.7 1.0 1.2 1 0 0 1 1 1 0 Prominin DUF883 PF05957.8 EGO58029.1 - 0.29 11.5 3.8 0.41 11.0 1.2 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) PEP-utilisers_N PF05524.8 EGO58029.1 - 0.9 9.3 5.8 4.6 7.0 4.0 2.0 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal SseC PF04888.7 EGO58029.1 - 7.3 5.8 29.8 0.61 9.3 8.4 2.1 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family CbiD PF01888.12 EGO58029.1 - 7.7 5.3 9.1 0.8 8.6 3.0 1.6 1 1 0 1 1 1 0 CbiD DUF4613 PF15390.1 EGO58029.1 - 8.8 4.3 9.1 10 4.1 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) SIN1 PF05422.7 EGO58031.1 - 3.1e-36 125.0 5.0 8.9e-20 70.6 0.0 3.4 3 1 0 3 3 3 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EGO58031.1 - 0.0035 17.2 0.0 0.0077 16.1 0.0 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG RBD PF02196.10 EGO58031.1 - 0.038 13.7 0.1 0.099 12.4 0.1 1.7 1 0 0 1 1 1 0 Raf-like Ras-binding domain PBP1_TM PF14812.1 EGO58031.1 - 4.4 7.6 14.7 3 8.2 1.6 3.7 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PRCC PF10253.4 EGO58032.1 - 4.6e-39 134.9 3.1 4.6e-39 134.9 2.1 2.7 3 1 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting SGL PF08450.7 EGO58033.1 - 4e-71 239.2 0.0 5e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region PD40 PF07676.7 EGO58033.1 - 0.0056 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat Reg_prop PF07494.6 EGO58033.1 - 0.0069 16.2 1.8 2.8 8.2 0.0 3.7 4 0 0 4 4 4 1 Two component regulator propeller Arylesterase PF01731.15 EGO58033.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Arylesterase Lactonase PF10282.4 EGO58033.1 - 0.087 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller bZIP_2 PF07716.10 EGO58035.1 - 3.2 7.6 14.4 4 7.3 9.1 1.7 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.16 EGO58035.1 - 4.3 7.3 13.9 27 4.7 9.6 2.1 1 1 0 1 1 1 0 bZIP transcription factor Amino_oxidase PF01593.19 EGO58036.1 - 0.001 18.2 0.2 0.001 18.2 0.1 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FadA PF09403.5 EGO58036.1 - 2.2 8.3 9.7 14 5.7 6.2 2.3 2 0 0 2 2 2 0 Adhesion protein FadA DUF2834 PF11196.3 EGO58038.1 - 0.00029 20.9 1.6 0.038 14.1 0.2 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2834) Arf PF00025.16 EGO58039.1 - 1e-39 135.5 0.0 1.7e-39 134.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EGO58039.1 - 1.5e-13 50.2 0.0 3.8e-09 35.7 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGO58039.1 - 1.1e-09 37.7 0.0 1.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EGO58039.1 - 3.5e-09 36.2 0.0 1.2e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 EGO58039.1 - 3e-07 29.8 0.0 6.7e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EGO58039.1 - 1.9e-05 24.1 0.0 7.3e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EGO58039.1 - 0.00015 22.2 0.0 0.00059 20.3 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGO58039.1 - 0.0022 17.9 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNase_PH PF01138.16 EGO58040.1 - 8.2e-23 81.1 0.0 1.2e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGO58040.1 - 3.6e-05 23.6 0.0 6.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 TolA PF06519.6 EGO58040.1 - 0.13 12.2 0.0 0.72 9.8 0.0 2.0 2 0 0 2 2 2 0 TolA C-terminal Cwf_Cwc_15 PF04889.7 EGO58041.1 - 2.3e-78 263.2 36.5 6.5e-76 255.2 25.3 2.0 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 EGO58041.1 - 0.21 11.0 24.5 0.21 11.0 16.1 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 EGO58041.1 - 1.3 6.9 32.3 1.9 6.3 22.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Snurportin1 PF11538.3 EGO58041.1 - 9.2 6.1 18.0 2.3 8.0 0.6 2.6 2 0 0 2 2 2 0 Snurportin1 BP28CT PF08146.7 EGO58042.1 - 1.9e-45 154.3 1.2 1.5e-43 148.2 0.2 3.8 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EGO58042.1 - 6.9e-27 93.8 0.2 6.9e-27 93.8 0.2 5.4 5 1 0 5 5 5 2 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 EGO58042.1 - 2.4e-08 34.1 17.3 0.025 14.8 0.1 7.4 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.17 EGO58042.1 - 0.00012 21.8 9.7 0.2 11.8 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat NOC3p PF07540.6 EGO58043.1 - 4.5e-31 106.9 0.4 4.5e-31 106.9 0.3 2.6 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 EGO58043.1 - 1.5e-26 92.8 0.1 1.5e-26 92.8 0.0 2.2 2 1 0 2 2 2 1 CBF/Mak21 family Asp PF00026.18 EGO58044.1 - 6.4e-69 232.6 1.1 7.6e-69 232.3 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO58044.1 - 2.5e-11 43.7 0.1 2.1e-10 40.7 0.0 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO58044.1 - 5.2e-07 30.0 0.2 0.36 11.3 0.0 3.6 3 0 0 3 3 3 3 Aspartyl protease TAXi_C PF14541.1 EGO58044.1 - 0.0095 15.4 0.0 0.06 12.8 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EGO58044.1 - 0.014 15.1 0.0 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 EGO58044.1 - 0.019 14.8 0.0 4 7.4 0.0 2.9 3 0 0 3 3 3 0 Retroviral aspartyl protease CFEM PF05730.6 EGO58045.1 - 0.0016 18.2 9.0 0.0029 17.4 6.3 1.4 1 0 0 1 1 1 1 CFEM domain STE PF02200.11 EGO58046.1 - 1.2e-61 205.7 0.3 2.4e-61 204.7 0.1 1.6 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 EGO58046.1 - 4e-12 45.7 11.2 3.8e-06 26.9 1.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO58046.1 - 1.5e-09 37.4 9.6 0.00032 20.7 1.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGO58046.1 - 3.1e-08 33.4 11.9 5e-08 32.8 2.2 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EGO58046.1 - 0.0001 22.0 1.1 0.0003 20.5 0.3 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EGO58046.1 - 0.0019 18.2 2.6 0.066 13.3 0.6 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EGO58046.1 - 0.17 12.2 3.2 0.34 11.3 2.2 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger Tmemb_cc2 PF10267.4 EGO58046.1 - 3 6.3 5.4 0.36 9.3 0.7 1.6 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Hydrophob_seed PF14547.1 EGO58047.1 - 0.057 13.3 0.2 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Hydrophobic seed protein Zn_clus PF00172.13 EGO58048.1 - 8.8e-07 28.7 9.3 1.6e-06 27.8 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGO58048.1 - 0.00026 19.9 0.0 0.0007 18.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain HEAT PF02985.17 EGO58049.1 - 8.8e-07 28.4 0.5 0.018 15.0 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EGO58049.1 - 2.2e-05 24.6 1.2 0.61 10.4 0.0 5.5 6 0 0 6 6 6 1 HEAT repeats DUF2435 PF10363.4 EGO58049.1 - 0.017 14.9 0.0 0.11 12.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 EGO58049.1 - 1.3 9.5 6.0 1.4 9.5 0.1 4.3 5 0 0 5 5 5 0 HEAT-like repeat EBP PF05241.7 EGO58050.1 - 1.3e-50 171.1 6.1 1.9e-50 170.5 4.2 1.2 1 0 0 1 1 1 1 Emopamil binding protein DUF572 PF04502.8 EGO58051.1 - 0.0054 15.9 11.7 0.0082 15.3 8.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) TFIIF_alpha PF05793.7 EGO58051.1 - 0.018 13.4 16.0 0.026 12.8 11.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA_13 PF13166.1 EGO58051.1 - 0.2 10.1 4.1 0.26 9.7 2.9 1.1 1 0 0 1 1 1 0 AAA domain OmpH PF03938.9 EGO58051.1 - 0.54 10.1 8.1 1.2 9.0 5.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1682 PF07946.9 EGO58051.1 - 1.3 7.8 9.3 2 7.2 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Activator_LAG-3 PF11498.3 EGO58051.1 - 3.5 6.2 5.3 5.6 5.6 3.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RNase_H2-Ydr279 PF09468.5 EGO58051.1 - 6.3 5.8 7.3 13 4.8 5.1 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) HCMV_UL139 PF12507.3 EGO58051.1 - 6.7 6.8 10.7 1.9 8.6 1.3 2.4 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein PHF5 PF03660.9 EGO58052.1 - 2e-51 172.5 10.6 2.3e-51 172.3 7.4 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EGO58052.1 - 0.91 9.3 15.7 0.19 11.5 5.4 2.8 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 EGO58052.1 - 1.4 8.7 15.8 2.9 7.6 0.5 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.24 EGO58052.1 - 5.9 6.6 15.3 0.2 11.3 4.5 2.5 1 1 1 2 2 2 0 PHD-finger Pinin_SDK_memA PF04696.8 EGO58053.1 - 3.5e-36 123.6 14.6 3.5e-36 123.6 10.1 2.0 3 0 0 3 3 3 1 pinin/SDK/memA/ protein conserved region DUF4119 PF13494.1 EGO58053.1 - 1.5 8.8 5.3 0.36 10.8 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) Abhydrolase_6 PF12697.2 EGO58054.1 - 1.3e-28 100.4 0.0 2.4e-28 99.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO58054.1 - 1e-12 48.0 0.0 1e-11 44.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO58054.1 - 6.3e-12 45.4 0.0 1.7e-11 44.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO58054.1 - 2.4e-05 24.1 0.0 4.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 EGO58054.1 - 0.004 17.0 0.0 0.0072 16.2 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Cript PF10235.4 EGO58055.1 - 2.4e-29 101.5 10.7 2.4e-29 101.5 7.4 1.4 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT zf-C3HC4_3 PF13920.1 EGO58055.1 - 0.2 11.3 14.9 4.7 6.9 7.0 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EGO58055.1 - 0.85 9.4 17.0 9.1 6.1 8.0 3.0 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.1 EGO58055.1 - 3.4 7.4 13.8 17 5.2 7.0 2.9 2 1 1 3 3 3 0 zinc-RING finger domain Ribosomal_L32p PF01783.18 EGO58055.1 - 4.4 7.5 10.1 0.44 10.7 3.1 2.3 2 1 1 3 3 3 0 Ribosomal L32p protein family DUF1272 PF06906.6 EGO58055.1 - 4.8 7.1 8.1 0.98 9.3 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-C4pol PF14260.1 EGO58055.1 - 5 7.2 13.1 13 5.8 0.2 2.8 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF2039 PF10217.4 EGO58055.1 - 5.9 6.9 19.8 1.2 9.1 7.7 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF1660 PF07874.6 EGO58055.1 - 8.2 6.7 9.8 4.8 7.5 3.6 2.5 2 1 0 2 2 2 0 Prophage protein (DUF1660) E1-E2_ATPase PF00122.15 EGO58056.1 - 1.7e-21 76.3 0.0 4.1e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EGO58056.1 - 2.1e-19 70.4 0.0 6.3e-19 68.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO58056.1 - 8.8e-17 62.2 0.9 1.3e-15 58.3 0.6 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO58056.1 - 3.5e-11 42.9 0.0 9.4e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGO58056.1 - 0.00049 19.7 0.6 0.0035 16.9 0.4 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGO58056.1 - 0.039 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Catalase PF00199.14 EGO58058.1 - 1.3e-157 524.4 0.5 1.7e-157 524.0 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGO58058.1 - 1.1e-19 70.0 0.1 2.2e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EGO58058.1 - 0.02 14.3 0.1 0.045 13.1 0.1 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family Nucleoside_tran PF01733.13 EGO58059.1 - 1.4e-31 109.8 6.1 1.4e-31 109.8 4.2 2.8 2 1 0 2 2 2 1 Nucleoside transporter DUF2404 PF10296.4 EGO58060.1 - 0.00037 20.5 0.0 0.0017 18.4 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Ins_P5_2-kin PF06090.7 EGO58061.1 - 2.5e-61 207.4 0.0 2.8e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase YEATS PF03366.11 EGO58062.1 - 1.3e-24 85.7 0.5 1.7e-24 85.3 0.4 1.1 1 0 0 1 1 1 1 YEATS family NAD_binding_10 PF13460.1 EGO58063.1 - 4e-14 53.0 0.0 4.3e-13 49.6 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGO58063.1 - 1.4e-06 27.9 0.0 2.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGO58063.1 - 0.00018 20.5 0.0 0.005 15.7 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EGO58063.1 - 0.00053 18.7 0.0 0.0014 17.3 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EGO58063.1 - 0.0052 16.7 0.0 0.0099 15.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.13 EGO58063.1 - 0.16 11.5 0.0 8 6.0 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SR-25 PF10500.4 EGO58065.1 - 0.22 10.9 24.3 0.23 10.9 16.8 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein tRNA_synt_1c_R2 PF04557.10 EGO58065.1 - 0.51 11.0 18.2 0.6 10.8 12.6 1.0 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 OAD_gamma PF04277.8 EGO58065.1 - 0.82 10.0 5.3 0.88 9.9 3.7 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain FLO_LFY PF01698.11 EGO58065.1 - 0.89 8.3 7.7 0.9 8.3 5.3 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein BLVR PF06375.6 EGO58065.1 - 2 8.2 25.7 2.8 7.7 17.8 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Agouti PF05039.7 EGO58065.1 - 2.1 8.7 7.0 2.3 8.6 4.9 1.1 1 0 0 1 1 1 0 Agouti protein Vfa1 PF08432.5 EGO58065.1 - 2.4 8.1 15.2 2.6 8.0 10.5 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Peptidase_S49_N PF08496.5 EGO58065.1 - 2.6 7.8 17.0 2.8 7.7 11.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Cucumo_2B PF03263.8 EGO58065.1 - 2.8 8.2 7.9 3.2 8.0 5.5 1.2 1 0 0 1 1 1 0 Cucumovirus protein 2B Rtf2 PF04641.7 EGO58065.1 - 2.9 7.0 16.1 3.2 6.8 11.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger YqfQ PF14181.1 EGO58065.1 - 4 7.4 12.2 4.2 7.3 8.5 1.1 1 0 0 1 1 1 0 YqfQ-like protein HA2 PF04408.18 EGO58065.1 - 4.9 7.2 5.6 4.8 7.2 3.9 1.2 1 0 0 1 1 1 0 Helicase associated domain (HA2) DUF3464 PF11947.3 EGO58065.1 - 5 6.5 8.6 5.3 6.4 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) RR_TM4-6 PF06459.7 EGO58065.1 - 5.1 6.9 9.4 5.1 6.9 6.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3807 PF12720.2 EGO58065.1 - 5.6 7.1 11.1 6 6.9 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) BRF1 PF07741.8 EGO58065.1 - 7.4 6.8 16.9 8.6 6.6 11.7 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Cnd1_N PF12922.2 EGO58065.1 - 7.4 6.1 8.7 8.4 5.9 6.0 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term DDHD PF02862.12 EGO58065.1 - 7.6 6.2 7.4 8.5 6.0 5.2 1.0 1 0 0 1 1 1 0 DDHD domain DUF3899 PF13038.1 EGO58065.1 - 7.6 6.7 8.1 9.7 6.4 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF4638 PF15472.1 EGO58065.1 - 9.6 5.7 15.4 10 5.5 10.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Kelch_5 PF13854.1 EGO58066.1 - 1.4e-12 47.2 14.0 1.4e-11 44.0 0.5 5.7 6 0 0 6 6 6 1 Kelch motif Kelch_4 PF13418.1 EGO58066.1 - 2.4e-06 27.1 10.6 0.054 13.2 0.1 6.4 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EGO58066.1 - 7.7e-06 25.8 12.7 2.2 8.5 0.1 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EGO58066.1 - 0.00056 19.5 4.2 16 5.4 0.0 5.6 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 EGO58066.1 - 0.0024 17.3 3.0 9.1 5.9 0.1 5.1 5 0 0 5 5 5 1 Kelch motif Flg_new PF09479.5 EGO58066.1 - 0.0094 15.9 1.4 0.039 13.9 1.0 2.1 1 0 0 1 1 1 1 Listeria-Bacteroides repeat domain (List_Bact_rpt) VSP PF03302.8 EGO58066.1 - 0.015 13.9 0.8 0.023 13.3 0.6 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF3609 PF12259.3 EGO58066.1 - 0.08 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) DUF1749 PF08538.5 EGO58067.1 - 1.5e-116 388.5 0.0 1.7e-116 388.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EGO58067.1 - 1.1e-14 54.8 0.2 1.8e-14 54.1 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO58067.1 - 1.3e-05 25.0 0.0 5.9e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO58067.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EGO58067.1 - 0.08 12.3 0.0 7.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF1057 PF06342.7 EGO58067.1 - 0.086 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) p450 PF00067.17 EGO58069.1 - 7.9e-49 166.4 0.0 1.1e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 eIF-5_eIF-2B PF01873.12 EGO58070.1 - 1.8e-39 134.2 0.0 3.1e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EGO58070.1 - 1.1e-25 89.3 2.2 1.1e-25 89.3 1.5 2.4 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Zn-ribbon_8 PF09723.5 EGO58070.1 - 0.023 14.6 2.0 0.064 13.2 1.4 1.8 1 0 0 1 1 1 0 Zinc ribbon domain CoaE PF01121.15 EGO58073.1 - 1.3e-41 141.9 0.0 7e-41 139.5 0.0 1.9 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EGO58073.1 - 0.00041 21.1 0.9 0.00099 19.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGO58073.1 - 0.036 14.3 0.3 0.26 11.6 0.0 2.4 2 1 1 3 3 3 0 AAA domain CcmH PF03918.9 EGO58073.1 - 0.2 10.6 0.9 0.32 9.9 0.6 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Tim17 PF02466.14 EGO58075.1 - 3.8e-26 91.6 3.9 5.2e-26 91.1 2.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2428 PF10350.4 EGO58076.1 - 3.5e-71 239.2 0.0 8.9e-71 237.8 0.0 1.8 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EGO58076.1 - 1.3e-08 34.1 9.5 0.47 10.6 0.0 8.2 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EGO58076.1 - 0.0026 18.2 2.8 1.1 9.8 0.0 5.2 4 0 0 4 4 4 1 HEAT-like repeat DUF2435 PF10363.4 EGO58076.1 - 0.0072 16.2 0.4 3.8 7.4 0.0 3.6 3 1 0 3 3 3 2 Protein of unknown function (DUF2435) Gtr1_RagA PF04670.7 EGO58080.1 - 2.4e-52 177.3 0.2 3.4e-52 176.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGO58080.1 - 0.0079 16.6 0.0 0.12 12.8 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein LMBR1 PF04791.11 EGO58081.1 - 1.9e-26 92.6 1.9 3.5e-26 91.8 1.3 1.3 1 1 0 1 1 1 1 LMBR1-like membrane protein Aldedh PF00171.17 EGO58082.1 - 1.3e-185 617.1 0.4 1.5e-185 617.0 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGO58082.1 - 6.5e-05 22.2 0.0 0.018 14.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Semialdhyde_dh PF01118.19 EGO58082.1 - 0.12 12.7 0.1 2 8.7 0.0 2.7 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain MIF PF01187.13 EGO58084.1 - 1e-05 25.5 0.0 2.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DUF3336 PF11815.3 EGO58085.1 - 9.8e-63 210.0 2.6 1.5e-62 209.3 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EGO58085.1 - 1.4e-20 74.0 0.0 6.5e-20 71.9 0.0 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Arf PF00025.16 EGO58086.1 - 1.2e-65 219.9 0.0 1.4e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EGO58086.1 - 6.1e-11 41.6 0.1 1.3e-07 30.6 0.0 2.3 1 1 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EGO58086.1 - 1.1e-08 35.5 0.0 1.5e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EGO58086.1 - 5.8e-08 32.1 0.0 7.4e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGO58086.1 - 9.2e-08 32.0 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EGO58086.1 - 1.6e-07 30.8 0.0 2.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGO58086.1 - 1.2e-06 27.8 0.0 1.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGO58086.1 - 0.0008 18.8 0.0 0.019 14.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EGO58086.1 - 0.11 11.9 0.0 0.27 10.6 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CENP-M PF11111.3 EGO58086.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Centromere protein M (CENP-M) cobW PF02492.14 EGO58086.1 - 0.15 11.4 0.0 10 5.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2457 PF10446.4 EGO58088.1 - 1.4e-174 581.1 27.2 1.4e-174 581.1 18.9 1.8 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) ATP-synt_DE_N PF02823.11 EGO58091.1 - 1.2e-19 69.8 0.1 1.9e-19 69.1 0.1 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain zf-C3HC4_2 PF13923.1 EGO58092.1 - 0.51 10.3 3.0 0.98 9.5 2.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Steroid_dh PF02544.11 EGO58093.1 - 1.1e-10 41.4 2.4 2.4e-10 40.3 1.7 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EGO58093.1 - 8.2e-05 22.0 1.0 0.00017 20.9 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ank_2 PF12796.2 EGO58094.1 - 3.3e-26 91.4 0.1 4.4e-18 65.4 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGO58094.1 - 1e-18 66.0 1.9 2.1e-06 27.2 0.2 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EGO58094.1 - 1.2e-16 60.2 1.7 4.1e-08 33.1 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO58094.1 - 9.9e-14 50.1 0.0 0.0003 20.7 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EGO58094.1 - 1.4e-13 50.9 0.2 1.3e-05 25.5 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) DHquinase_II PF01220.14 EGO58094.1 - 0.097 11.9 0.0 5.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Dehydroquinase class II TGS PF02824.16 EGO58095.1 - 6.1e-23 80.4 0.2 1.2e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EGO58095.1 - 2.9e-18 65.9 0.0 9.9e-18 64.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO58095.1 - 6.9e-10 38.4 0.1 3.5e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EGO58095.1 - 1.6e-05 24.4 0.2 0.3 10.4 0.0 3.7 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EGO58095.1 - 4.9e-05 23.2 0.1 0.012 15.4 0.0 2.3 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 EGO58095.1 - 0.006 15.3 0.3 0.022 13.5 0.0 1.9 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 EGO58095.1 - 0.0089 16.5 0.0 0.1 13.1 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 EGO58095.1 - 0.029 13.4 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Arf PF00025.16 EGO58095.1 - 0.052 12.7 0.1 8.7 5.5 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family HTH_Tnp_Tc5 PF03221.11 EGO58100.1 - 1.4e-11 44.0 0.0 4.6e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EGO58100.1 - 9.7e-05 21.7 0.0 0.00039 19.7 0.0 2.0 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain DUF1970 PF09301.5 EGO58100.1 - 0.013 15.5 0.5 0.15 12.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) MarR PF01047.17 EGO58100.1 - 0.02 14.6 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 MarR family HTH_38 PF13936.1 EGO58100.1 - 0.042 13.4 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.1 EGO58100.1 - 0.047 13.2 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease PXA PF02194.10 EGO58102.1 - 1.1e-43 148.9 0.9 2.5e-43 147.7 0.6 1.5 1 0 0 1 1 1 1 PXA domain zf-Mss51 PF13824.1 EGO58103.1 - 3.5e-26 90.8 7.7 7.6e-26 89.7 5.3 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 EGO58103.1 - 0.015 15.1 0.9 0.015 15.1 0.6 2.2 2 0 0 2 2 2 0 MYND finger GFA PF04828.9 EGO58103.1 - 0.21 11.5 2.4 0.5 10.3 0.2 2.2 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme RTX_C PF08339.5 EGO58103.1 - 4.4 7.0 6.0 5.4 6.7 0.7 2.2 2 0 0 2 2 2 0 RTX C-terminal domain Peptidase_M35 PF02102.10 EGO58103.1 - 5.3 5.5 6.3 8.2 4.9 4.4 1.1 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family CPSF_A PF03178.10 EGO58104.1 - 7.8e-103 343.9 0.0 1.5e-101 339.6 0.0 2.7 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EGO58104.1 - 4.3e-54 183.5 0.0 5e-53 179.9 0.0 2.1 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 EGO58104.1 - 0.031 14.1 0.1 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat Lipase_GDSL_2 PF13472.1 EGO58105.1 - 7.5e-20 71.8 0.0 9.2e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGO58105.1 - 4.5e-18 65.9 0.0 5.5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Fimbrial_CS1 PF04449.7 EGO58105.1 - 0.05 13.6 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 CS1 type fimbrial major subunit DUF919 PF06034.6 EGO58106.1 - 0.037 13.6 0.5 0.065 12.8 0.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Methyltransf_23 PF13489.1 EGO58110.1 - 2.9e-16 59.5 0.1 1.2e-15 57.6 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO58110.1 - 6.5e-08 32.9 0.0 1.7e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO58110.1 - 1.5e-07 31.0 0.0 4.5e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO58110.1 - 1.8e-06 28.3 0.0 4.9e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO58110.1 - 3.3e-06 27.6 0.0 5.7e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO58110.1 - 0.00058 18.9 0.0 0.0012 17.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EGO58110.1 - 0.0013 18.7 0.0 0.046 13.7 0.0 3.0 3 0 0 3 3 3 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EGO58110.1 - 0.014 14.5 0.0 0.037 13.1 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EGO58110.1 - 0.037 13.1 0.0 0.071 12.1 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 EGO58110.1 - 0.065 12.6 0.0 0.5 9.7 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase small domain Epimerase PF01370.16 EGO58112.1 - 4.7e-52 176.7 0.0 6e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGO58112.1 - 1.8e-19 69.7 0.0 2.3e-18 66.1 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EGO58112.1 - 2.2e-19 69.3 0.0 3.1e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EGO58112.1 - 1.3e-18 66.9 0.0 1.6e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EGO58112.1 - 1.1e-14 53.8 0.0 1.4e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGO58112.1 - 6.8e-09 35.9 0.0 9.1e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Brix PF04427.13 EGO58113.1 - 3.2e-31 108.4 0.0 5e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Brix domain YL1 PF05764.8 EGO58113.1 - 0.0086 15.7 7.4 0.0086 15.7 5.2 2.3 2 0 0 2 2 2 1 YL1 nuclear protein Sporozoite_P67 PF05642.6 EGO58113.1 - 0.27 9.0 3.8 0.4 8.4 2.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 EGO58113.1 - 1.2 6.9 25.5 1.7 6.4 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family tRNA-synt_2b PF00587.20 EGO58114.1 - 6.6e-67 224.4 0.1 1.6e-66 223.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGO58114.1 - 2.2e-21 75.6 1.9 8.8e-21 73.6 0.0 2.8 3 0 0 3 3 3 1 Anticodon binding domain F420_oxidored PF03807.12 EGO58114.1 - 0.077 13.4 0.1 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EGO58114.1 - 0.079 13.2 0.3 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Pkinase PF00069.20 EGO58115.1 - 1.9e-71 240.2 0.0 3.1e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO58115.1 - 2.6e-54 184.0 0.0 4.3e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EGO58115.1 - 4.5e-23 81.4 1.0 1.8e-22 79.5 0.1 2.6 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EGO58115.1 - 1.9e-08 33.6 0.0 3.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 EGO58115.1 - 1.3e-06 28.6 0.2 3.9e-06 27.1 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 EGO58115.1 - 0.0041 16.9 0.1 0.0041 16.9 0.1 2.6 3 1 1 4 4 4 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGO58115.1 - 0.059 12.2 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3635 PF12330.3 EGO58116.1 - 3.2e-10 39.9 0.0 7.3e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) BTK PF00779.14 EGO58118.1 - 0.0088 15.6 0.3 0.018 14.6 0.2 1.5 1 0 0 1 1 1 1 BTK motif CHORD PF04968.7 EGO58118.1 - 0.011 15.9 1.9 0.011 15.9 1.3 2.7 2 1 0 2 2 2 0 CHORD PDT PF00800.13 EGO58119.1 - 2.9e-54 183.3 0.0 3.8e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EGO58119.1 - 0.00016 21.1 0.0 0.0013 18.1 0.0 2.3 2 0 0 2 2 2 1 ACT domain eRF1_2 PF03464.10 EGO58120.1 - 1.2e-44 151.9 0.0 2.2e-44 151.0 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EGO58120.1 - 5.2e-41 139.4 0.6 9.8e-41 138.5 0.4 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EGO58120.1 - 1.8e-28 98.7 0.0 3.1e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 DUF1770 PF08589.5 EGO58121.1 - 7e-30 103.5 9.9 1e-29 103.0 6.8 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) PBP1_TM PF14812.1 EGO58121.1 - 0.35 11.1 2.3 0.58 10.4 1.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WHIM1 PF15612.1 EGO58122.1 - 6.8e-07 28.9 0.0 1.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Daxx PF03344.10 EGO58122.1 - 0.0023 16.5 17.0 0.0023 16.5 11.8 1.5 2 0 0 2 2 2 1 Daxx Family WHIM2 PF15613.1 EGO58122.1 - 0.04 13.8 0.4 0.1 12.5 0.3 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 Astro_capsid PF03115.9 EGO58122.1 - 0.39 8.9 6.4 0.56 8.4 4.5 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor BUD22 PF09073.5 EGO58122.1 - 0.47 9.4 18.9 0.87 8.5 13.1 1.4 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.9 EGO58122.1 - 1.8 8.0 11.0 18 4.7 8.6 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Nop14 PF04147.7 EGO58122.1 - 2.6 5.8 29.5 0.036 12.0 15.3 1.5 2 0 0 2 2 2 0 Nop14-like family Ribosomal_L2_C PF03947.13 EGO58123.1 - 1.9e-37 127.9 4.2 1.9e-37 127.9 2.9 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EGO58123.1 - 5.8e-15 55.0 0.2 1.1e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.19 EGO58124.1 - 4.5e-66 223.0 0.0 5.3e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EGO58124.1 - 0.0053 15.9 0.0 0.0092 15.2 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase ArfGap PF01412.13 EGO58125.1 - 0.034 13.9 0.1 0.043 13.6 0.0 1.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf EST1_DNA_bind PF10373.4 EGO58126.1 - 8.1e-47 159.7 0.1 1.5e-46 158.8 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EGO58126.1 - 2.8e-28 98.5 0.5 8.4e-28 96.9 0.0 2.1 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EGO58126.1 - 0.025 14.1 0.1 0.097 12.3 0.0 2.0 1 0 0 1 1 1 0 TPR repeat zf-C2H2_4 PF13894.1 EGO58127.1 - 2.1 8.8 11.5 5.8 7.4 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO58127.1 - 2.2 8.7 13.5 0.4 11.1 0.6 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF629 PF04780.7 EGO58127.1 - 2.6 6.4 4.2 5 5.5 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) PRCC PF10253.4 EGO58127.1 - 3.6 8.2 9.4 0.44 11.2 1.1 2.2 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting G10 PF01125.12 EGO58128.1 - 5.9e-60 201.0 3.9 6.6e-60 200.8 2.7 1.0 1 0 0 1 1 1 1 G10 protein Complex1_LYR PF05347.10 EGO58129.1 - 2e-08 33.9 0.5 4.2e-08 32.8 0.1 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGO58129.1 - 1.9e-06 27.9 0.3 4.1e-06 26.9 0.2 1.7 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EGO58129.1 - 6.3e-05 23.4 0.1 8e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like dDENN PF03455.14 EGO58129.1 - 0.1 12.6 0.3 1.3 9.1 0.1 2.1 2 0 0 2 2 2 0 dDENN domain Mito_fiss_reg PF05308.6 EGO58131.1 - 0.066 12.5 6.6 0.11 11.8 4.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EGO58131.1 - 0.38 10.0 2.4 0.6 9.3 1.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SNF5 PF04855.7 EGO58133.1 - 4.7e-77 258.7 1.0 7.5e-77 258.0 0.7 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.19 EGO58134.1 - 5.2e-10 39.2 0.1 7.1e-10 38.8 0.1 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.24 EGO58135.1 - 2.3e-14 52.7 18.8 5e-10 38.9 5.4 2.4 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.1 EGO58135.1 - 0.066 13.3 5.9 0.066 13.3 1.4 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain PHD_2 PF13831.1 EGO58135.1 - 0.47 9.8 9.2 1.3 8.4 2.2 2.9 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 EGO58135.1 - 0.63 9.8 10.7 0.85 9.3 0.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 EGO58135.1 - 0.68 9.2 12.6 0.27 10.5 2.5 3.2 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EGO58135.1 - 3.6 7.3 15.2 1.5 8.6 0.1 2.8 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HEAT PF02985.17 EGO58136.1 - 3.1e-06 26.7 0.4 0.78 9.9 0.0 5.2 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EGO58136.1 - 7.3e-06 26.1 2.8 0.00094 19.4 0.1 4.6 4 1 1 5 5 5 2 HEAT repeats NEP PF10167.4 EGO58136.1 - 0.0085 15.7 1.9 0.13 12.0 0.2 2.7 2 0 0 2 2 2 1 Uncharacterised conserved protein HEAT_EZ PF13513.1 EGO58136.1 - 0.011 16.2 1.5 0.56 10.7 0.0 4.5 5 0 0 5 5 5 0 HEAT-like repeat Lactamase_B_2 PF12706.2 EGO58138.1 - 1.7e-12 47.2 0.0 2.3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGO58138.1 - 1.8e-07 31.0 0.1 2.8e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Amidohydro_2 PF04909.9 EGO58138.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase YjeF_N PF03853.10 EGO58139.1 - 3.7e-40 137.2 0.0 5.8e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EGO58139.1 - 6.8e-17 61.9 0.2 6.8e-17 61.9 0.1 2.6 3 0 0 3 3 3 1 FDF domain Nha1_C PF08619.5 EGO58142.1 - 4.1e-97 326.2 52.7 3.9e-95 319.6 36.5 2.0 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EGO58142.1 - 2.5e-69 233.6 22.2 3e-69 233.3 15.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EGO58142.1 - 0.35 10.8 2.1 0.5 10.3 0.2 2.1 2 0 0 2 2 2 0 YrhC-like protein PRP4 PF08799.6 EGO58142.1 - 2.4 7.4 8.8 6.9 6.0 0.4 2.7 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like Tom22 PF04281.8 EGO58143.1 - 2.1e-45 153.6 0.1 2.6e-45 153.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF605 PF04652.11 EGO58144.1 - 0.86 8.9 16.2 1.1 8.5 11.3 1.2 1 0 0 1 1 1 0 Vta1 like PP2C PF00481.16 EGO58145.1 - 5.4e-62 209.4 0.9 6.7e-51 173.1 0.1 3.2 1 1 2 3 3 3 3 Protein phosphatase 2C Snf7 PF03357.16 EGO58146.1 - 1.1e-35 122.5 19.7 1.7e-35 121.9 13.7 1.2 1 0 0 1 1 1 1 Snf7 V_ATPase_I PF01496.14 EGO58146.1 - 0.012 13.5 2.4 0.014 13.2 1.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ist1 PF03398.9 EGO58146.1 - 0.12 11.7 6.8 0.22 10.9 4.7 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DFF40 PF09230.5 EGO58146.1 - 1.4 8.2 6.5 1.5 8.1 4.1 1.3 1 1 0 1 1 1 0 DNA fragmentation factor 40 kDa CaMBD PF02888.11 EGO58146.1 - 5.1 6.9 8.1 1.1 9.1 2.5 2.1 1 1 1 2 2 2 0 Calmodulin binding domain Dynamin_N PF00350.18 EGO58147.1 - 9e-19 67.9 0.9 2e-17 63.4 0.0 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EGO58147.1 - 5.3e-09 36.0 0.1 2.4e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO58147.1 - 3.1e-07 30.0 3.1 1.4e-06 27.8 1.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 EGO58147.1 - 0.0066 16.7 0.3 0.066 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain BLOC1_2 PF10046.4 EGO58147.1 - 0.018 15.1 4.0 0.46 10.6 2.6 2.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IIGP PF05049.8 EGO58147.1 - 0.022 13.6 0.0 0.052 12.3 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PduV-EutP PF10662.4 EGO58147.1 - 0.027 13.9 0.1 4.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FH2 PF02181.18 EGO58147.1 - 0.034 13.0 2.2 0.063 12.1 1.5 1.4 1 0 0 1 1 1 0 Formin Homology 2 Domain Miro PF08477.8 EGO58147.1 - 0.035 14.5 0.1 0.56 10.7 0.0 2.8 2 1 0 2 2 2 0 Miro-like protein ApoLp-III PF07464.6 EGO58147.1 - 0.04 13.9 3.4 0.13 12.2 2.4 1.8 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) AAA_29 PF13555.1 EGO58147.1 - 0.056 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1184 PF06683.6 EGO58147.1 - 0.057 13.0 0.8 0.12 12.0 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1184) DUF445 PF04286.7 EGO58147.1 - 0.5 9.8 4.5 0.53 9.7 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) CN_hydrolase PF00795.17 EGO58148.1 - 1.2e-18 67.1 0.1 1.9e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase A_deaminase PF00962.17 EGO58149.1 - 9e-30 103.7 0.0 1.1e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase WD40 PF00400.27 EGO58152.1 - 5e-48 159.3 22.0 9.1e-10 38.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EGO58152.1 - 9.8e-05 22.1 0.1 0.074 12.7 0.0 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EGO58152.1 - 0.093 11.0 0.0 0.63 8.2 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain Phosducin PF02114.11 EGO58153.1 - 8e-10 37.8 0.0 1.8e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 Phosducin Ran_BP1 PF00638.13 EGO58155.1 - 2.5e-49 166.3 1.0 5.8e-49 165.1 0.7 1.6 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EGO58155.1 - 0.0022 17.7 0.2 0.0086 15.7 0.2 1.8 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.9 EGO58155.1 - 0.0087 15.6 1.6 0.0096 15.4 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) PS-DH PF14765.1 EGO58155.1 - 0.012 14.7 0.6 0.024 13.8 0.4 1.4 1 0 0 1 1 1 0 Polyketide synthase dehydratase YEATS PF03366.11 EGO58156.1 - 2e-26 91.5 0.1 6.1e-26 89.9 0.0 1.9 1 0 0 1 1 1 1 YEATS family Zn_clus PF00172.13 EGO58157.1 - 5.7e-07 29.3 12.1 8.9e-07 28.7 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 EGO58158.1 - 1e-46 159.2 0.0 1.4e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO58158.1 - 2e-06 28.6 0.4 8.9e-06 26.5 0.0 2.3 2 1 1 3 3 3 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.16 EGO58159.1 - 1.2e-62 211.9 0.0 1.8e-62 211.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGO58159.1 - 0.0031 16.7 0.0 0.0052 15.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EGO58159.1 - 0.014 14.1 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGO58159.1 - 0.14 10.4 0.0 0.24 9.6 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF4211 PF13926.1 EGO58161.1 - 2.6e-15 56.1 0.2 2.1e-14 53.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) Polysacc_lyase PF14099.1 EGO58162.1 - 0.086 12.4 6.9 0.17 11.5 4.8 1.5 1 1 0 1 1 1 0 Polysaccharide lyase MFS_2 PF13347.1 EGO58163.1 - 4.5e-10 38.5 6.3 4.5e-10 38.5 4.3 2.8 3 0 0 3 3 3 1 MFS/sugar transport protein Methyltransf_23 PF13489.1 EGO58164.1 - 9.6e-15 54.6 0.0 1.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO58164.1 - 1e-09 38.7 0.0 2.1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO58164.1 - 8.9e-08 32.5 0.0 5e-07 30.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO58164.1 - 2.9e-07 30.1 0.0 0.0019 17.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EGO58164.1 - 3.4e-06 27.6 0.0 7.5e-05 23.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO58164.1 - 0.0041 17.4 0.0 0.022 15.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO58164.1 - 0.011 14.8 0.0 0.14 11.2 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EGO58164.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 EGO58164.1 - 0.034 14.1 0.1 0.1 12.6 0.1 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 EGO58164.1 - 0.051 12.9 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Na_H_Exchanger PF00999.16 EGO58165.1 - 4.8e-68 229.4 36.0 6e-68 229.0 25.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glycoprotein_B PF00606.13 EGO58165.1 - 0.062 11.3 0.3 0.11 10.5 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B FadA PF09403.5 EGO58166.1 - 1 9.3 8.6 1.7 8.6 6.0 1.2 1 0 0 1 1 1 0 Adhesion protein FadA OmpH PF03938.9 EGO58166.1 - 2.4 8.1 8.4 3.8 7.4 5.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DDRGK PF09756.4 EGO58166.1 - 3.4 7.0 16.7 5.5 6.3 11.6 1.2 1 0 0 1 1 1 0 DDRGK domain CENP-H PF05837.7 EGO58166.1 - 5 7.3 10.3 8.7 6.5 7.1 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SAM_2 PF07647.12 EGO58167.1 - 3.8e-17 61.9 0.0 6.6e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGO58167.1 - 1.4e-16 60.3 0.0 2.6e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EGO58167.1 - 4.2e-14 52.7 0.0 8.1e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain IGR PF09597.5 EGO58167.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 IGR protein motif MAPEG PF01124.13 EGO58168.1 - 8.1e-14 51.3 1.7 1e-13 51.0 1.2 1.1 1 0 0 1 1 1 1 MAPEG family HTH_36 PF13730.1 EGO58168.1 - 0.0091 16.1 0.0 0.04 14.0 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain DUF4445 PF14574.1 EGO58168.1 - 0.091 10.9 0.1 0.11 10.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4445) RRM_6 PF14259.1 EGO58169.1 - 1e-12 47.8 0.0 1.7e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO58169.1 - 9.7e-12 44.3 0.1 1.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO58169.1 - 0.00063 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec8_exocyst PF04048.9 EGO58170.1 - 0.13 11.9 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain MerR-DNA-bind PF09278.6 EGO58170.1 - 0.16 12.4 0.4 0.27 11.6 0.3 1.3 1 0 0 1 1 1 0 MerR, DNA binding Gly-zipper_OmpA PF13436.1 EGO58170.1 - 0.95 9.1 6.2 0.51 10.0 0.1 2.1 1 1 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Fmp27 PF10344.4 EGO58171.1 - 7.2e-249 828.0 0.0 1.1e-248 827.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EGO58171.1 - 2.1e-173 577.3 0.3 5.1e-173 576.1 0.0 1.9 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EGO58171.1 - 2.3e-164 547.3 0.2 6.3e-164 545.8 0.1 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EGO58171.1 - 2e-55 187.0 0.0 4.4e-55 185.8 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EGO58171.1 - 3.2e-53 179.6 0.1 8.7e-53 178.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EGO58171.1 - 1.1e-32 112.5 0.0 3.5e-32 110.9 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain ELFV_dehydrog PF00208.16 EGO58173.1 - 1.5e-61 208.1 0.0 2.9e-61 207.1 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EGO58173.1 - 2.5e-23 81.6 0.0 1.2e-17 62.7 0.0 2.5 2 1 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EGO58173.1 - 0.00048 19.7 0.1 0.0026 17.3 0.0 2.2 3 0 0 3 3 3 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Aminotran_5 PF00266.14 EGO58174.1 - 1.5e-17 63.3 0.1 3.2e-13 49.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGO58174.1 - 3.5e-05 22.2 0.0 5.5e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGO58174.1 - 0.00021 20.4 0.0 0.00036 19.6 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_L32e PF01655.13 EGO58175.1 - 1.7e-50 169.6 2.2 2.3e-50 169.2 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 DnaJ PF00226.26 EGO58176.1 - 8.4e-26 89.4 2.1 1.8e-25 88.4 1.4 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGO58176.1 - 9.6e-22 76.6 0.1 1.5e-18 66.4 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EGO58176.1 - 3.8e-14 52.4 15.7 6.6e-14 51.7 10.8 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EGO58176.1 - 0.00026 20.6 3.8 0.14 11.8 0.0 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family UreE_N PF02814.10 EGO58176.1 - 0.016 14.6 0.1 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain JAB PF01398.16 EGO58177.1 - 7.4e-29 99.8 0.1 1.5e-28 98.8 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EGO58177.1 - 4e-06 26.3 0.0 7.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain PDH PF02153.12 EGO58178.1 - 6.1e-16 58.0 0.1 9.3e-16 57.4 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.14 EGO58178.1 - 0.038 13.1 0.0 0.074 12.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EGO58178.1 - 0.094 13.1 0.3 0.46 10.9 0.2 2.2 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EGO58178.1 - 0.11 12.2 0.1 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RCC1 PF00415.13 EGO58179.1 - 6.9e-35 119.0 13.8 3.6e-09 36.7 0.2 7.2 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGO58179.1 - 2.2e-19 68.5 30.2 4e-06 26.2 0.4 6.5 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.8 EGO58180.1 - 4.7e-80 268.3 0.0 5.5e-80 268.1 0.0 1.0 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 EGO58180.1 - 0.072 11.8 0.1 0.12 11.0 0.1 1.5 1 1 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 TBP-binding PF09247.6 EGO58181.1 - 0.11 12.7 0.0 0.52 10.5 0.0 2.1 2 1 0 2 2 2 0 TATA box-binding protein binding LRR_4 PF12799.2 EGO58181.1 - 0.12 12.0 4.1 2.8 7.6 0.0 4.5 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) CDC37_N PF03234.9 EGO58182.1 - 7.4e-61 205.5 4.8 7.4e-61 205.5 3.3 2.6 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EGO58182.1 - 3.7e-51 173.0 0.8 3.7e-51 173.0 0.6 2.4 3 0 0 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EGO58182.1 - 2.7e-29 100.9 2.7 2.7e-29 100.9 1.9 2.6 2 0 0 2 2 2 1 Cdc37 C terminal domain XPG_I_2 PF12813.2 EGO58182.1 - 0.0059 16.1 1.9 0.016 14.6 0.0 2.5 2 1 1 3 3 3 1 XPG domain containing hGDE_central PF14702.1 EGO58182.1 - 0.01 15.0 0.1 0.01 15.0 0.0 1.9 2 0 0 2 2 2 0 central domain of human glycogen debranching enzyme Borrelia_REV PF03978.8 EGO58182.1 - 0.099 12.3 8.6 0.051 13.3 2.7 2.7 3 0 0 3 3 3 0 Borrelia burgdorferi REV protein SPATA25 PF15218.1 EGO58184.1 - 0.055 12.9 0.0 0.068 12.5 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 25 SBDS_C PF09377.5 EGO58185.1 - 3.9e-52 175.1 0.4 6e-52 174.5 0.2 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EGO58185.1 - 1.3e-30 105.0 0.3 3.3e-30 103.7 0.2 1.8 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Allexi_40kDa PF05549.6 EGO58185.1 - 0.012 14.8 1.3 0.59 9.3 0.0 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein FlxA PF14282.1 EGO58185.1 - 0.02 14.8 0.5 0.047 13.6 0.4 1.6 1 0 0 1 1 1 0 FlxA-like protein Enoyl_reductase PF12241.3 EGO58185.1 - 0.038 12.9 0.2 0.062 12.2 0.1 1.3 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Peptidase_S10 PF00450.17 EGO58186.1 - 4.9e-131 437.7 0.2 6.3e-131 437.3 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EGO58186.1 - 1.2e-06 28.6 0.3 2.1e-06 27.8 0.2 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 EGO58186.1 - 0.00051 19.9 0.0 0.0085 15.9 0.0 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family PDEase_I PF00233.14 EGO58187.1 - 6.9e-39 133.9 0.0 5.3e-36 124.5 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase UCH PF00443.24 EGO58188.1 - 3.2e-76 255.9 0.0 3.7e-42 144.2 0.0 2.6 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO58188.1 - 3e-18 66.2 0.0 2.9e-09 36.8 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EGO58188.1 - 1.2e-10 41.7 0.0 2.9e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 DUSP domain Peptidase_M16_C PF05193.16 EGO58189.1 - 7.5e-40 136.5 0.0 2.1e-22 79.6 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGO58189.1 - 1.7e-34 118.6 3.2 5.4e-34 117.0 0.1 3.1 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) zf-CCHC PF00098.18 EGO58190.1 - 5.3e-05 22.9 4.4 8.6e-05 22.2 3.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EGO58190.1 - 0.0069 15.8 0.6 0.014 14.8 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle TP53IP5 PF15331.1 EGO58190.1 - 5.2 6.9 10.6 1.1 9.1 1.0 2.9 2 1 1 3 3 3 0 Cellular tumour antigen p53-inducible 5 zf-CHCC PF10276.4 EGO58191.1 - 2.1e-16 59.4 0.9 3.1e-16 58.9 0.6 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 EGO58191.1 - 0.015 14.9 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb zf-C2H2_4 PF13894.1 EGO58191.1 - 0.14 12.5 1.6 1.9 9.0 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO58191.1 - 0.25 11.7 2.8 0.78 10.2 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Methyltransf_18 PF12847.2 EGO58194.1 - 1.5e-21 77.0 0.0 2.2e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO58194.1 - 1e-11 44.6 0.0 1e-10 41.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO58194.1 - 1.6e-08 34.6 0.0 3e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO58194.1 - 8.3e-08 32.5 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO58194.1 - 9.2e-08 32.4 0.0 2.3e-07 31.2 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO58194.1 - 1.4e-06 28.1 0.0 2.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO58194.1 - 6.5e-06 26.5 0.0 9.1e-05 22.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO58194.1 - 0.0001 21.7 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EGO58194.1 - 0.00045 19.9 0.0 0.00066 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGO58194.1 - 0.0031 17.5 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase AdoMet_MTase PF07757.8 EGO58194.1 - 0.0038 17.3 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.7 EGO58194.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW HEAT PF02985.17 EGO58195.1 - 1.7e-42 139.6 14.0 0.0065 16.4 0.1 13.1 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 EGO58195.1 - 9e-31 106.0 4.8 1e-08 35.3 0.0 7.6 3 3 3 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.2 EGO58195.1 - 4.7e-11 42.9 6.3 0.013 15.8 0.1 7.6 5 2 3 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EGO58195.1 - 2.3e-09 37.4 11.1 0.21 12.1 0.1 9.0 7 2 3 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.15 EGO58195.1 - 5.4e-07 28.3 9.2 0.00041 18.7 0.2 5.1 4 1 2 6 6 6 2 Adaptin N terminal region DUF2435 PF10363.4 EGO58195.1 - 0.0034 17.2 4.0 0.63 9.9 0.2 4.5 5 0 0 5 5 5 1 Protein of unknown function (DUF2435) CLASP_N PF12348.3 EGO58195.1 - 0.0039 16.5 5.5 2.1 7.6 0.3 4.6 5 2 1 6 6 6 2 CLASP N terminal Arm PF00514.18 EGO58195.1 - 0.012 15.4 4.5 1.7 8.6 0.0 4.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat MadL PF03817.8 EGO58195.1 - 0.057 13.2 0.1 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Malonate transporter MadL subunit Cnd3 PF12719.2 EGO58195.1 - 0.059 12.3 0.5 0.71 8.8 0.2 2.6 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.2 EGO58195.1 - 0.29 10.9 6.4 2.4 7.9 0.3 4.4 4 2 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Myotub-related PF06602.9 EGO58196.1 - 4.7e-126 420.3 0.0 6.1e-126 419.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EGO58196.1 - 0.028 14.6 0.1 0.098 12.9 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 EGO58196.1 - 0.14 11.5 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_S3_C PF00189.15 EGO58197.1 - 1.3e-16 60.5 0.1 2.6e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EGO58197.1 - 2.5e-12 46.1 0.1 4.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EGO58197.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mg_trans_NIPA PF05653.9 EGO58198.1 - 3e-99 331.7 8.0 3.8e-99 331.4 5.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EGO58198.1 - 5.8e-08 32.9 2.1 5.8e-08 32.9 1.5 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EGO58198.1 - 0.00043 20.3 7.1 0.00043 20.3 4.9 3.3 2 1 1 3 3 3 2 EamA-like transporter family Adap_comp_sub PF00928.16 EGO58201.1 - 1.1e-18 67.3 0.0 1.6e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGO58201.1 - 1.3e-08 34.6 0.1 2.2e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Apc4 PF12896.2 EGO58202.1 - 5.1e-36 123.9 0.6 9.2e-36 123.1 0.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 WD40 PF00400.27 EGO58202.1 - 0.011 15.6 0.0 0.53 10.2 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat PH PF00169.24 EGO58203.1 - 0.00016 21.8 0.2 0.00066 19.8 0.1 2.1 1 1 0 1 1 1 1 PH domain GRAM PF02893.15 EGO58203.1 - 0.022 14.2 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 GRAM domain RRM_6 PF14259.1 EGO58204.1 - 3e-10 39.9 0.0 6.8e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO58204.1 - 1.2e-08 34.4 0.0 0.00081 18.9 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO58204.1 - 2.3e-07 30.5 0.0 2.1e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EGO58205.1 - 0.00025 20.8 4.4 5.3 7.0 0.0 5.2 4 0 0 4 4 4 3 WD domain, G-beta repeat IKI3 PF04762.7 EGO58205.1 - 0.066 11.0 0.0 10 3.7 0.0 3.0 3 1 0 3 3 3 0 IKI3 family MoaC PF01967.16 EGO58206.1 - 8e-47 158.3 0.1 2e-46 157.0 0.1 1.7 1 1 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 EGO58206.1 - 4e-34 117.0 0.0 2.2e-33 114.6 0.0 2.1 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EGO58206.1 - 3.5e-18 66.3 0.0 6.5e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EGO58206.1 - 3.3e-05 24.0 0.0 9.9e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EGO58206.1 - 4.7e-05 23.4 0.0 0.00027 20.9 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Synaptobrevin PF00957.16 EGO58207.1 - 1.8e-14 53.1 0.6 3e-14 52.3 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EGO58207.1 - 7.4e-13 47.8 0.0 1.3e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 Regulated-SNARE-like domain EzrA PF06160.7 EGO58207.1 - 0.039 12.1 2.3 0.031 12.4 0.6 1.5 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Imm43 PF15602.1 EGO58207.1 - 0.091 12.7 0.4 0.87 9.5 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 43 FYVE PF01363.16 EGO58208.1 - 3.7e-16 58.7 8.6 5.8e-16 58.1 6.0 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 EGO58208.1 - 1.3 9.0 14.2 0.21 11.4 6.5 2.0 2 0 0 2 2 2 0 AN1-like Zinc finger ELO PF01151.13 EGO58210.1 - 4e-84 281.8 10.3 5e-84 281.5 7.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family WG_beta_rep PF14903.1 EGO58211.1 - 0.067 13.4 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 WG containing repeat GMC_oxred_N PF00732.14 EGO58212.1 - 4.9e-44 150.6 0.8 6.6e-44 150.2 0.6 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGO58212.1 - 2e-24 86.5 0.1 7.9e-24 84.5 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EGO58212.1 - 2.9e-08 33.0 0.2 0.0005 19.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO58212.1 - 5.3e-07 28.8 2.6 9.6e-07 27.9 1.8 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EGO58212.1 - 2.4e-06 27.5 0.8 1.2e-05 25.3 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO58212.1 - 2.2e-05 23.6 0.0 6.3e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EGO58212.1 - 9.2e-05 22.4 1.8 0.00021 21.2 0.9 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGO58212.1 - 0.0026 16.3 0.3 0.0039 15.7 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EGO58212.1 - 0.011 14.9 0.3 0.024 13.7 0.2 1.5 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 EGO58212.1 - 0.056 13.0 0.1 0.091 12.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EGO58212.1 - 0.12 11.2 0.4 1.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A GDI PF00996.13 EGO58212.1 - 0.15 10.3 0.0 0.3 9.3 0.0 1.4 1 0 0 1 1 1 0 GDP dissociation inhibitor UDPG_MGDP_dh_N PF03721.9 EGO58212.1 - 0.27 10.5 2.9 0.47 9.8 2.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3074 PF11274.3 EGO58213.1 - 5.4e-59 198.9 6.0 1.7e-56 190.8 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3074) FliL PF03748.9 EGO58213.1 - 1.9 8.5 6.9 20 5.2 0.0 3.1 2 1 0 2 2 2 0 Flagellar basal body-associated protein FliL Pyr_redox_2 PF07992.9 EGO58216.1 - 4.2e-25 88.8 0.0 2.7e-24 86.1 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO58216.1 - 1.9e-13 50.5 0.0 1.1e-11 44.9 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGO58216.1 - 0.0042 17.1 0.1 1.1 9.3 0.0 3.2 2 1 1 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase RskA PF10099.4 EGO58216.1 - 0.019 14.7 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Tubulin_3 PF14881.1 EGO58217.1 - 5.8e-82 273.5 0.0 8.9e-82 272.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EGO58217.1 - 2.2e-42 143.7 0.1 6.5e-42 142.2 0.1 1.9 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EGO58217.1 - 1.6e-07 31.3 0.0 0.0079 16.0 0.0 2.4 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain PAP_central PF04928.12 EGO58219.1 - 1.2e-104 348.6 0.0 1.7e-104 348.1 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EGO58219.1 - 3.9e-50 169.4 0.0 1.3e-49 167.7 0.0 1.9 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EGO58219.1 - 1.1e-07 32.0 0.3 4.6e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain Abhydrolase_5 PF12695.2 EGO58220.1 - 9.2e-06 25.4 2.2 6.6e-05 22.6 1.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EGO58220.1 - 3.6e-05 23.4 0.1 0.00014 21.4 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EGO58220.1 - 4.3e-05 23.5 1.7 7.8e-05 22.6 1.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EGO58220.1 - 0.00047 20.4 0.2 0.0013 19.0 0.2 1.7 1 1 0 1 1 1 1 Thioesterase domain DUF676 PF05057.9 EGO58220.1 - 0.003 16.9 0.0 0.006 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EGO58220.1 - 0.0088 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 EGO58220.1 - 0.017 14.7 0.0 0.054 13.0 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF4366 PF14283.1 EGO58220.1 - 0.03 13.7 0.1 0.046 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Abhydrolase_2 PF02230.11 EGO58220.1 - 0.043 13.2 0.0 0.087 12.2 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2413 PF10310.4 EGO58220.1 - 0.05 12.4 2.0 0.071 11.9 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF2305 PF10230.4 EGO58220.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Prenyltrans_1 PF13243.1 EGO58220.1 - 1.8 8.6 5.4 4.2 7.4 2.7 2.3 2 1 0 2 2 2 0 Prenyltransferase-like PTPLA PF04387.9 EGO58221.1 - 5.5e-54 182.0 9.8 8.1e-54 181.4 6.8 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Methyltransf_23 PF13489.1 EGO58224.1 - 1.5e-13 50.7 0.0 2.5e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO58224.1 - 9.2e-09 35.6 0.0 1.6e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO58224.1 - 8.7e-08 32.5 0.0 2e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO58224.1 - 4.5e-06 27.2 0.0 7.2e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO58224.1 - 2.5e-05 23.9 0.0 0.00036 20.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO58224.1 - 0.00048 19.3 0.0 0.0028 16.8 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EGO58224.1 - 0.0042 16.1 0.0 0.009 15.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EGO58224.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Arf PF00025.16 EGO58225.1 - 3.6e-75 251.0 0.1 4.1e-75 250.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGO58225.1 - 1.4e-13 50.5 0.0 1.7e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGO58225.1 - 6.3e-12 45.1 0.0 7.5e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EGO58225.1 - 1.8e-11 43.3 0.4 1.1e-07 30.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EGO58225.1 - 2.6e-09 37.5 0.0 3.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EGO58225.1 - 4.9e-09 35.6 0.0 5.9e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGO58225.1 - 2.1e-06 27.6 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO58225.1 - 4.1e-06 26.3 0.1 0.0006 19.3 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 EGO58225.1 - 0.0015 17.3 0.4 0.0074 15.1 0.1 2.1 2 1 0 2 2 2 1 ArgK protein FeoB_N PF02421.13 EGO58225.1 - 0.01 15.1 0.8 0.044 13.0 0.5 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF3986 PF13143.1 EGO58225.1 - 0.1 13.0 0.2 0.27 11.7 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Ribosomal_L39 PF00832.15 EGO58226.1 - 1.2e-22 79.0 8.8 1.3e-22 78.9 6.1 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Skp1 PF01466.14 EGO58227.1 - 7.1e-40 134.9 1.5 1.6e-39 133.8 1.0 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EGO58227.1 - 9.2e-22 76.9 0.1 2e-21 75.8 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 EGO58227.1 - 0.049 13.6 1.8 0.052 13.5 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Glyco_transf_22 PF03901.12 EGO58228.1 - 2e-49 168.7 13.1 1.3e-26 93.5 0.8 2.1 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family DUF2346 PF09803.4 EGO58229.1 - 0.0001 22.0 6.8 0.00029 20.6 4.7 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Cas_Csy4 PF09618.5 EGO58229.1 - 0.074 12.8 0.2 0.084 12.6 0.1 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Transcrip_reg PF01709.15 EGO58230.1 - 5.5e-58 195.8 1.3 6.3e-58 195.6 0.9 1.0 1 0 0 1 1 1 1 Transcriptional regulator Phasin_2 PF09361.5 EGO58230.1 - 0.029 14.3 0.2 6.1 6.9 0.0 2.9 3 0 0 3 3 3 0 Phasin protein HEAT_2 PF13646.1 EGO58231.1 - 4.9e-15 55.5 6.6 0.0002 21.5 0.0 8.5 6 1 1 8 8 8 4 HEAT repeats Vac14_Fab1_bd PF12755.2 EGO58231.1 - 2.4e-10 40.6 0.4 0.002 18.5 0.0 5.5 5 0 0 5 5 5 3 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EGO58231.1 - 1e-09 37.6 20.5 0.017 15.1 0.0 10.9 10 0 0 10 10 10 3 HEAT repeat CLASP_N PF12348.3 EGO58231.1 - 2.5e-05 23.7 2.9 0.042 13.2 0.1 4.7 6 0 0 6 6 6 2 CLASP N terminal DUF1640 PF07798.6 EGO58232.1 - 2.3e-12 47.2 2.1 2.9e-12 46.9 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Abhydrolase_6 PF12697.2 EGO58233.1 - 1.1e-17 64.7 0.2 2e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO58233.1 - 1.8e-13 50.4 0.0 1e-11 44.7 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO58233.1 - 1.2e-08 34.7 0.0 1.2e-07 31.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.15 EGO58233.1 - 3.4e-08 33.1 0.0 1.1e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EGO58233.1 - 0.00017 21.6 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Esterase PF00756.15 EGO58233.1 - 0.00043 19.7 0.0 0.00087 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.20 EGO58233.1 - 0.0011 18.5 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EGO58233.1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 EGO58233.1 - 0.0018 17.7 0.0 0.0032 16.9 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Y_phosphatase PF00102.22 EGO58233.1 - 0.003 16.9 0.0 0.0058 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase BAAT_C PF08840.6 EGO58233.1 - 0.0036 17.0 0.0 2.1 8.0 0.0 3.0 2 1 1 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 EGO58233.1 - 0.011 15.1 0.0 0.16 11.3 0.0 2.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Ser_hydrolase PF06821.8 EGO58233.1 - 0.025 14.1 0.0 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase LCAT PF02450.10 EGO58233.1 - 0.043 12.8 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.8 EGO58233.1 - 0.047 13.2 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3530 PF12048.3 EGO58233.1 - 0.054 12.4 0.0 0.094 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Thioesterase PF00975.15 EGO58233.1 - 0.056 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.13 EGO58233.1 - 0.061 12.5 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family VirJ PF06057.6 EGO58233.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_4 PF08386.5 EGO58233.1 - 0.17 11.7 0.6 3.9 7.4 0.0 2.6 3 0 0 3 3 2 0 TAP-like protein DUF900 PF05990.7 EGO58233.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) SnoaL_2 PF12680.2 EGO58234.1 - 0.026 14.9 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Alk_phosphatase PF00245.15 EGO58235.1 - 1.3e-107 360.0 0.0 1.6e-107 359.8 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EGO58235.1 - 2e-05 24.1 0.0 4.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.4 EGO58235.1 - 0.0014 18.4 0.1 0.0035 17.0 0.1 1.7 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF3357 PF11837.3 EGO58235.1 - 0.0029 17.4 0.2 0.0056 16.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) Sulfatase PF00884.18 EGO58235.1 - 0.0039 16.4 0.1 0.62 9.1 0.0 2.2 2 0 0 2 2 2 2 Sulfatase DUF3328 PF11807.3 EGO58235.1 - 0.057 13.1 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) HLH PF00010.21 EGO58236.1 - 1.8e-12 46.7 0.3 4.1e-12 45.6 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DivIC PF04977.10 EGO58236.1 - 0.009 15.4 4.6 0.018 14.4 3.1 1.6 1 1 0 1 1 1 1 Septum formation initiator Pox_A30L_A26L PF06086.7 EGO58236.1 - 0.029 13.8 0.1 0.047 13.1 0.1 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein Alpha_GJ PF03229.8 EGO58236.1 - 0.55 10.5 5.7 1 9.6 4.0 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J PAT1 PF09770.4 EGO58236.1 - 1.3 7.1 19.9 1.5 6.9 13.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CLTH PF10607.4 EGO58237.1 - 1.6e-33 115.4 0.0 3.1e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EGO58237.1 - 0.015 15.0 0.1 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 LisH CAF1 PF04857.15 EGO58238.1 - 3.5e-70 236.3 0.2 9.2e-70 234.9 0.0 1.7 2 0 0 2 2 2 1 CAF1 family ribonuclease TFIIA PF03153.8 EGO58238.1 - 0.1 12.4 22.6 0.45 10.3 8.9 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AIF_C PF14721.1 EGO58238.1 - 0.26 11.5 4.0 5.2 7.3 1.6 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Neur_chan_memb PF02932.11 EGO58238.1 - 1.1 9.0 6.7 0.53 10.1 2.3 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4557 PF15101.1 EGO58238.1 - 3.6 7.3 11.6 6.4 6.5 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Hid1 PF12722.2 EGO58238.1 - 8.2 3.9 9.3 0.38 8.3 2.7 1.4 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein NDUF_B12 PF08122.7 EGO58239.1 - 2.1e-15 56.1 0.1 2.8e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family ATG16 PF08614.6 EGO58240.1 - 0.016 15.0 0.5 0.016 15.0 0.4 2.0 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF2570 PF10828.3 EGO58240.1 - 0.035 13.7 1.0 0.063 12.8 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) MAD PF05557.8 EGO58240.1 - 0.21 9.6 4.6 0.12 10.4 1.7 1.5 2 0 0 2 2 2 0 Mitotic checkpoint protein Med9 PF07544.8 EGO58240.1 - 0.34 10.6 4.3 4.6 7.0 0.5 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 APG6 PF04111.7 EGO58240.1 - 0.49 9.3 2.7 0.74 8.8 1.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SlyX PF04102.7 EGO58240.1 - 0.89 9.9 4.3 6.5 7.2 2.2 2.7 2 0 0 2 2 2 0 SlyX eIF-6 PF01912.13 EGO58241.1 - 4e-84 280.6 0.7 5.1e-84 280.3 0.5 1.1 1 0 0 1 1 1 1 eIF-6 family Zein-binding PF04576.10 EGO58242.1 - 0.6 10.2 2.1 0.45 10.6 0.1 1.8 2 0 0 2 2 2 0 Zein-binding ThiF PF00899.16 EGO58243.1 - 1.1e-12 47.9 0.2 1.8e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 ThiF family Cornichon PF03311.9 EGO58243.1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Cornichon protein DUF2431 PF10354.4 EGO58245.1 - 3.5e-54 183.2 0.0 4.2e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) DUF3238 PF11579.3 EGO58245.1 - 0.014 14.9 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3238) Methyltransf_26 PF13659.1 EGO58245.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2841 PF11001.3 EGO58246.1 - 1.3e-40 138.2 2.0 1.3e-40 138.2 1.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) UBN2_3 PF14244.1 EGO58246.1 - 0.021 14.3 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type TSSC4 PF15264.1 EGO58247.1 - 0.086 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 ABC_membrane PF00664.18 EGO58248.1 - 3.7e-83 279.0 22.4 6.2e-45 153.7 6.2 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGO58248.1 - 3.3e-52 176.4 0.0 8.1e-30 103.9 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGO58248.1 - 1.2e-10 40.9 0.8 8.1e-05 21.9 0.0 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGO58248.1 - 1.4e-05 25.2 0.4 0.027 14.4 0.5 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EGO58248.1 - 1.7e-05 24.7 0.0 0.17 11.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 EGO58248.1 - 6.9e-05 22.9 0.5 1.3 8.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EGO58248.1 - 0.00016 21.1 0.0 0.087 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EGO58248.1 - 0.00023 21.6 0.1 0.7 10.4 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 EGO58248.1 - 0.00039 20.8 0.6 0.091 13.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EGO58248.1 - 0.0004 19.6 0.1 0.22 10.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EGO58248.1 - 0.001 18.6 0.4 0.73 9.3 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGO58248.1 - 0.0015 18.0 1.5 2 8.0 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EGO58248.1 - 0.0033 16.9 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 EGO58248.1 - 0.0035 17.1 0.6 0.42 10.4 0.0 2.5 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.12 EGO58248.1 - 0.0067 16.2 1.2 0.27 11.0 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 RNA_helicase PF00910.17 EGO58248.1 - 0.069 13.3 0.0 8.8 6.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase T2SE PF00437.15 EGO58248.1 - 0.071 11.9 1.7 0.14 10.9 0.1 2.1 2 1 0 3 3 3 0 Type II/IV secretion system protein GTP_EFTU PF00009.22 EGO58248.1 - 0.088 12.2 0.1 11 5.3 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGO58248.1 - 0.11 12.6 0.7 16 5.6 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGO58248.1 - 0.11 13.3 0.0 11 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EGO58248.1 - 0.15 11.6 2.1 0.6 9.7 0.0 2.7 3 0 0 3 3 3 0 NACHT domain AIG1 PF04548.11 EGO58248.1 - 0.34 9.9 0.8 7.7 5.5 0.0 2.3 2 0 0 2 2 2 0 AIG1 family TFIIF_alpha PF05793.7 EGO58248.1 - 4.2 5.6 4.9 7.3 4.8 3.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UPF0047 PF01894.12 EGO58249.1 - 1.1e-40 138.0 0.0 1.3e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 NUDIX_2 PF13869.1 EGO58250.1 - 7.1e-82 273.2 0.0 8.4e-82 273.0 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF4316 PF14195.1 EGO58250.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) Dynamin_N PF00350.18 EGO58251.1 - 3.6e-17 62.6 0.0 3.5e-16 59.4 0.0 2.6 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EGO58251.1 - 5.2e-06 26.4 0.1 0.0016 18.3 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EGO58251.1 - 2.7e-05 24.4 3.4 9.8e-05 22.6 0.0 3.3 3 1 0 4 4 4 1 ABC transporter DUF258 PF03193.11 EGO58251.1 - 0.0014 17.8 0.0 0.005 16.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NB-ARC PF00931.17 EGO58251.1 - 0.0026 16.6 0.0 0.0071 15.2 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain Prominin PF05478.6 EGO58251.1 - 0.003 15.1 6.7 0.011 13.2 0.2 2.6 3 0 0 3 3 3 2 Prominin Zeta_toxin PF06414.7 EGO58251.1 - 0.0049 16.0 0.1 0.017 14.2 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AIG1 PF04548.11 EGO58251.1 - 0.011 14.9 0.1 0.1 11.6 0.1 2.5 2 0 0 2 2 2 0 AIG1 family Miro PF08477.8 EGO58251.1 - 0.019 15.4 0.2 0.073 13.5 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 EGO58251.1 - 0.023 14.8 0.5 0.42 10.7 0.0 3.2 4 0 0 4 4 3 0 AAA domain AAA_17 PF13207.1 EGO58251.1 - 0.026 15.3 1.9 0.52 11.1 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 EGO58251.1 - 0.038 13.5 0.0 0.096 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EGO58251.1 - 1.3 9.3 9.3 4.3 7.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF4611 PF15387.1 EGO58252.1 - 2.5 8.3 9.8 0.78 9.9 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Peptidase_M28 PF04389.12 EGO58253.1 - 8.2e-42 142.9 0.0 1.2e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Pkinase PF00069.20 EGO58254.1 - 4.9e-77 258.5 0.0 5.9e-77 258.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO58254.1 - 3.8e-38 131.0 0.3 6e-38 130.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO58254.1 - 0.0016 17.4 0.0 0.0052 15.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGO58254.1 - 0.015 14.4 0.1 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SCA7 PF08313.7 EGO58256.1 - 9.5e-34 114.8 0.5 2.8e-33 113.3 0.3 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain Mito_carr PF00153.22 EGO58257.1 - 2.1e-47 158.7 1.6 4.1e-15 55.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.2 EGO58257.1 - 0.027 14.8 0.0 0.21 11.9 0.0 2.3 2 0 0 2 2 2 0 YtxH-like protein SR-25 PF10500.4 EGO58257.1 - 6 6.2 24.4 13 5.1 16.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-C3HC4_2 PF13923.1 EGO58258.1 - 1.4e-08 34.6 17.7 2.1e-05 24.4 2.7 3.0 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO58258.1 - 1.1e-05 25.0 5.5 1.1e-05 25.0 3.8 3.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGO58258.1 - 1.3e-05 24.7 15.1 3.9e-05 23.2 4.1 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO58258.1 - 4.2e-05 23.2 17.2 0.00046 19.9 4.1 3.4 3 1 1 4 4 4 2 Ring finger domain zf-RING_UBOX PF13445.1 EGO58258.1 - 5.3e-05 22.8 3.1 5.3e-05 22.8 2.2 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EGO58258.1 - 7e-05 22.4 21.9 0.00064 19.3 2.1 3.4 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EGO58258.1 - 0.00014 21.6 13.2 0.00072 19.4 4.8 3.1 2 1 0 2 2 2 1 FYVE zinc finger Rtf2 PF04641.7 EGO58258.1 - 0.0013 18.0 10.8 0.0013 18.0 7.5 3.1 2 2 0 2 2 1 1 Rtf2 RING-finger Rad50_zn_hook PF04423.9 EGO58258.1 - 0.045 13.2 11.7 0.2 11.1 1.7 3.6 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.1 EGO58258.1 - 0.091 12.6 14.3 0.81 9.6 3.6 3.5 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EGO58258.1 - 1.2 8.9 5.9 7.4 6.4 0.2 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DZR PF12773.2 EGO58258.1 - 2.1 8.2 17.1 2.4 8.0 2.9 3.7 2 2 1 3 3 3 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 EGO58258.1 - 6.9 6.5 12.7 1.6 8.5 1.3 3.3 3 0 0 3 3 3 0 zinc-ribbons Acyltransferase PF01553.16 EGO58259.1 - 1.3e-14 53.7 0.0 3.6e-14 52.3 0.0 1.7 1 1 0 1 1 1 1 Acyltransferase NTF2 PF02136.15 EGO58261.1 - 5.7e-25 87.9 0.1 9.4e-25 87.2 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EGO58261.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 EGO58261.1 - 0.61 8.2 31.1 0.89 7.7 21.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PH_9 PF15410.1 EGO58262.1 - 2.6e-12 46.9 0.0 4.1e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EGO58262.1 - 7.5e-06 26.0 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 PH domain Keratin_B2 PF01500.12 EGO58263.1 - 0.0045 16.7 5.3 0.005 16.6 3.7 1.1 1 0 0 1 1 1 1 Keratin, high sulfur B2 protein Nnf1 PF03980.9 EGO58264.1 - 3.4e-32 110.6 0.0 1.6e-31 108.5 0.0 2.3 1 0 0 1 1 1 1 Nnf1 Cytochrom_B561 PF03188.11 EGO58264.1 - 0.029 14.1 8.8 0.075 12.8 6.1 1.7 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EGO58264.1 - 0.2 11.2 3.7 0.43 10.1 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) PIR PF00399.14 EGO58266.1 - 4.6e-17 60.6 43.4 0.00018 20.7 0.6 6.6 6 0 0 6 6 6 6 Yeast PIR protein repeat HMG_box PF00505.14 EGO58267.1 - 1e-08 35.3 3.8 5.6e-06 26.5 1.1 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EGO58267.1 - 0.0019 18.5 2.6 0.0019 18.5 1.8 2.9 3 0 0 3 3 3 1 HMG-box domain DUF2280 PF10045.4 EGO58267.1 - 0.012 15.5 1.5 4.4 7.2 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) K_channel_TID PF07941.6 EGO58267.1 - 0.67 10.2 14.8 0.31 11.3 1.3 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Cpn60_TCP1 PF00118.19 EGO58268.1 - 5.2e-138 460.6 7.9 5.9e-138 460.5 5.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PH_10 PF15411.1 EGO58270.1 - 1.7e-26 92.6 0.1 2.8e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 EGO58270.1 - 7.2e-11 42.0 0.0 2.2e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EGO58270.1 - 1.9e-07 30.9 0.0 3.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 EGO58270.1 - 8.8e-07 28.6 6.6 1.7e-06 27.7 4.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGO58270.1 - 0.004 17.2 2.0 0.01 15.9 1.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGO58270.1 - 0.0079 15.8 2.7 0.014 15.0 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO58270.1 - 0.0097 15.6 6.2 0.016 14.8 4.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGO58270.1 - 0.1 12.6 5.3 0.18 11.8 3.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1147 PF06615.6 EGO58270.1 - 0.11 12.3 0.3 0.29 10.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-C3HC4 PF00097.20 EGO58270.1 - 0.21 11.2 6.1 0.38 10.4 4.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EGO58270.1 - 0.27 11.2 4.0 0.46 10.5 2.8 1.4 1 0 0 1 1 1 0 RING-like domain DUF1272 PF06906.6 EGO58270.1 - 6.2 6.7 6.2 16 5.4 4.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) MFS_1 PF07690.11 EGO58271.1 - 2.3e-22 79.2 37.0 1.3e-21 76.6 25.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO58271.1 - 2.5e-06 25.9 17.2 7.6e-06 24.4 11.9 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3098 PF11297.3 EGO58271.1 - 0.067 12.9 2.9 0.29 10.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) Saccharop_dh PF03435.13 EGO58272.1 - 8.6e-18 64.4 0.0 4e-17 62.2 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase Ribosomal_L37ae PF01780.14 EGO58274.1 - 1e-38 131.0 7.5 1.1e-38 130.9 5.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EGO58274.1 - 0.0035 17.1 3.3 0.0053 16.5 2.3 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain GCC2_GCC3 PF07699.8 EGO58274.1 - 0.0072 15.8 0.4 0.011 15.3 0.3 1.3 1 0 0 1 1 1 1 GCC2 and GCC3 DUF1364 PF07102.7 EGO58274.1 - 0.018 14.8 0.5 0.026 14.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) zf-BED PF02892.10 EGO58274.1 - 0.023 14.4 4.9 1.1 9.1 0.2 2.3 1 1 1 2 2 2 0 BED zinc finger NCD3G PF07562.9 EGO58274.1 - 0.054 13.2 1.1 0.079 12.6 0.7 1.3 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR A2L_zn_ribbon PF08792.5 EGO58274.1 - 0.067 12.6 2.3 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.1 EGO58274.1 - 0.068 13.4 1.2 0.89 9.9 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 EGO58274.1 - 0.082 12.8 1.7 0.55 10.2 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 EGO58274.1 - 0.082 12.5 1.2 0.11 12.1 0.8 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Tnp_zf-ribbon_2 PF13842.1 EGO58274.1 - 0.088 13.2 3.7 0.22 11.9 2.3 1.8 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon CarbpepA_inh PF02977.10 EGO58274.1 - 0.1 12.1 0.7 0.1 12.1 0.5 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Elf1 PF05129.8 EGO58274.1 - 0.16 11.6 3.0 0.3 10.7 2.1 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2 PF00096.21 EGO58274.1 - 0.34 11.3 3.5 0.9 10.0 0.5 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type NOB1_Zn_bind PF08772.6 EGO58274.1 - 0.34 10.7 4.0 3.4 7.5 2.8 2.2 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-met PF12874.2 EGO58274.1 - 0.47 10.7 2.4 1.9 8.8 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF581 PF04570.9 EGO58274.1 - 0.93 8.8 3.4 9.3 5.6 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF581) C1_4 PF07975.7 EGO58274.1 - 1.5 8.8 4.0 6 6.9 0.3 2.1 1 1 2 3 3 3 0 TFIIH C1-like domain PHD PF00628.24 EGO58275.1 - 4.6e-10 39.0 6.0 4.6e-10 39.0 4.1 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 EGO58275.1 - 1.2e-06 28.2 3.4 1.2e-06 28.2 2.3 4.2 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EGO58275.1 - 0.00052 20.0 6.3 0.00052 20.0 4.4 3.1 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGO58275.1 - 0.00063 19.3 2.0 0.00063 19.3 1.4 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 EGO58275.1 - 0.00094 18.4 2.7 0.00094 18.4 1.9 2.4 2 0 0 2 2 2 1 PHD-finger zf-RING_5 PF14634.1 EGO58275.1 - 0.0015 18.1 2.5 0.0015 18.1 1.7 3.6 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGO58275.1 - 0.0033 17.0 3.6 0.0033 17.0 2.5 3.7 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGO58275.1 - 0.0099 15.7 2.8 0.0099 15.7 1.9 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 EGO58275.1 - 0.019 14.6 1.4 0.019 14.6 1.0 3.2 5 0 0 5 5 4 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 EGO58275.1 - 0.02 14.1 1.3 0.02 14.1 0.9 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain DZR PF12773.2 EGO58275.1 - 0.089 12.6 4.8 0.12 12.2 0.6 2.6 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_4 PF14447.1 EGO58275.1 - 0.67 9.5 8.0 0.14 11.6 0.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Prim_Zn_Ribbon PF08273.7 EGO58275.1 - 1.8 8.6 7.3 12 6.0 0.1 3.2 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-C3HC4_2 PF13923.1 EGO58275.1 - 2.3 8.3 21.2 0.035 14.1 1.2 3.9 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) MRP-L46 PF11788.3 EGO58276.1 - 1.4e-35 122.3 0.2 2.3e-35 121.5 0.1 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EGO58276.1 - 1.8e-06 27.6 0.3 3.9e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain CAF1 PF04857.15 EGO58277.1 - 4.2e-26 91.8 0.0 5.5e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease DUF155 PF02582.9 EGO58278.1 - 3.4e-55 186.6 1.6 4.4e-55 186.2 0.5 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 DUF3535 PF12054.3 EGO58280.1 - 4e-154 513.4 0.4 2.2e-153 511.0 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EGO58280.1 - 1.3e-73 247.4 0.0 1.9e-73 246.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 EGO58280.1 - 3.6e-14 51.5 7.7 0.012 15.6 0.0 8.9 8 0 0 8 8 8 4 HEAT repeat Helicase_C PF00271.26 EGO58280.1 - 5.2e-13 48.6 0.0 1.2e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 EGO58280.1 - 2.1e-06 28.0 1.6 0.85 10.0 0.0 3.9 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EGO58280.1 - 2.4e-05 24.5 11.6 0.015 15.5 0.0 7.2 7 2 1 8 8 8 1 HEAT repeats HEAT_EZ PF13513.1 EGO58280.1 - 0.011 16.1 14.0 13 6.3 0.0 9.3 10 0 0 10 10 10 0 HEAT-like repeat SMC_N PF02463.14 EGO58282.1 - 4.7e-63 212.3 9.4 7.7e-63 211.6 6.5 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGO58282.1 - 6.8e-21 74.4 0.0 5.1e-20 71.6 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EGO58282.1 - 1.5e-17 64.5 16.2 1.5e-17 64.5 11.3 7.2 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.1 EGO58282.1 - 1e-14 55.1 9.9 8.8e-08 32.4 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EGO58282.1 - 0.00044 19.7 0.0 0.0011 18.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DEAD PF00270.24 EGO58282.1 - 0.0025 17.3 2.9 1 8.8 0.0 3.8 3 1 0 3 3 3 2 DEAD/DEAH box helicase Reo_sigmaC PF04582.7 EGO58282.1 - 0.14 11.3 10.0 5.4 6.1 0.0 4.4 5 0 0 5 5 5 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 EGO58282.1 - 0.3 11.4 0.0 0.3 11.4 0.0 6.0 3 2 1 4 4 4 0 ABC transporter Velvet PF11754.3 EGO58284.1 - 8.5e-55 185.5 0.0 1.9e-54 184.3 0.0 1.5 1 0 0 1 1 1 1 Velvet factor PGA2 PF07543.7 EGO58284.1 - 0.73 9.6 5.7 0.71 9.6 2.7 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 U3_snoRNA_assoc PF08297.6 EGO58286.1 - 1.5e-12 47.5 3.2 1.5e-12 47.5 2.2 4.4 3 1 0 3 3 3 1 U3 snoRNA associated DUF1501 PF07394.7 EGO58286.1 - 5 5.8 9.0 8.8 5.0 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) TIM PF00121.13 EGO58287.1 - 7.3e-91 303.5 0.2 8.2e-91 303.3 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 EGO58287.1 - 0.094 11.9 0.0 0.3 10.2 0.0 1.7 1 1 1 2 2 2 0 CutC family L51_S25_CI-B8 PF05047.11 EGO58288.1 - 3.1e-16 58.8 0.0 5.5e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.3 EGO58289.1 - 3.3e-33 113.8 2.8 6.2e-33 112.9 1.9 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EGO58289.1 - 5.2e-16 58.0 0.1 2.3e-15 55.9 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO58289.1 - 1.8e-11 43.8 0.0 3.7e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO58289.1 - 1.9e-10 40.4 0.0 4.3e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L10 PF00466.15 EGO58290.1 - 2.5e-24 85.1 0.0 3.6e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 ABC_membrane PF00664.18 EGO58291.1 - 1.4e-91 306.7 37.9 5.5e-49 167.0 10.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGO58291.1 - 3.2e-67 225.0 0.0 1.6e-32 112.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGO58291.1 - 2.7e-12 46.3 0.0 0.00047 19.4 0.0 3.9 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGO58291.1 - 4e-10 40.1 1.6 0.04 13.8 0.1 4.3 2 2 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EGO58291.1 - 5e-09 35.5 1.0 0.0005 19.5 0.2 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EGO58291.1 - 1e-08 35.4 1.4 0.00026 21.0 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EGO58291.1 - 3.7e-08 32.3 4.6 0.003 16.2 0.1 3.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EGO58291.1 - 4.3e-07 29.2 0.0 0.11 11.6 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGO58291.1 - 1e-06 29.5 0.2 0.1 13.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EGO58291.1 - 4.7e-06 26.1 3.1 0.081 12.3 0.0 4.3 5 0 0 5 5 5 2 AAA domain AAA PF00004.24 EGO58291.1 - 0.00018 21.7 3.2 2.3 8.4 0.1 4.7 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EGO58291.1 - 0.00086 19.1 2.2 0.96 9.4 0.1 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EGO58291.1 - 0.0014 18.7 2.9 2.4 8.2 0.3 3.7 2 2 0 2 2 2 2 AAA domain G-alpha PF00503.15 EGO58291.1 - 0.0017 17.1 0.1 0.37 9.4 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_33 PF13671.1 EGO58291.1 - 0.0022 17.8 0.0 3.3 7.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGO58291.1 - 0.0034 17.6 0.1 4.4 7.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EGO58291.1 - 0.0085 16.0 1.3 0.78 9.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EGO58291.1 - 0.012 15.3 0.1 9.8 5.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EGO58291.1 - 0.013 15.3 0.1 6.5 6.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.1 EGO58291.1 - 0.024 14.9 0.0 2.3 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EGO58291.1 - 0.034 13.9 3.3 6.7 6.4 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 MobB PF03205.9 EGO58291.1 - 0.073 12.7 2.9 15 5.2 0.0 3.8 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EGO58291.1 - 0.087 12.3 1.6 27 4.1 0.0 3.7 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 EGO58291.1 - 0.091 12.9 0.0 17 5.6 0.0 3.4 3 0 0 3 3 2 0 RNA helicase AAA_10 PF12846.2 EGO58291.1 - 0.097 12.0 5.6 12 5.1 0.2 4.1 4 1 0 5 5 4 0 AAA-like domain MMR_HSR1 PF01926.18 EGO58291.1 - 0.11 12.4 0.3 11 5.9 0.1 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF1183 PF06682.7 EGO58292.1 - 7.8e-98 327.9 10.6 1.1e-97 327.5 7.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) BRE1 PF08647.6 EGO58293.1 - 2e-29 101.4 4.2 2e-29 101.4 2.9 6.2 4 2 2 6 6 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.1 EGO58293.1 - 1.2e-08 34.5 7.6 1.9e-08 33.8 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO58293.1 - 1.3e-08 34.7 9.3 2.2e-08 33.9 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO58293.1 - 1.4e-07 31.0 8.7 2.7e-07 30.1 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO58293.1 - 1.9e-07 30.6 9.8 3.5e-07 29.8 6.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGO58293.1 - 1.2e-06 28.2 7.0 2.2e-06 27.3 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain Snapin_Pallidin PF14712.1 EGO58293.1 - 9.1e-05 22.6 6.0 9.1e-05 22.6 4.2 6.3 4 3 3 7 7 7 1 Snapin/Pallidin zf-RING_UBOX PF13445.1 EGO58293.1 - 0.00017 21.2 5.1 0.00051 19.7 3.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger DUF1192 PF06698.6 EGO58293.1 - 0.00034 20.3 26.0 0.0019 17.9 0.6 6.9 4 1 1 6 6 6 2 Protein of unknown function (DUF1192) Prok-RING_4 PF14447.1 EGO58293.1 - 0.00055 19.4 2.1 0.001 18.5 1.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EGO58293.1 - 0.0017 18.1 4.5 0.0037 17.0 3.1 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DUF904 PF06005.7 EGO58293.1 - 0.0072 16.6 1.9 0.0072 16.6 1.3 8.1 4 3 2 6 6 6 4 Protein of unknown function (DUF904) zf-C3HC4_4 PF15227.1 EGO58293.1 - 0.01 15.6 6.8 0.022 14.6 4.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGO58293.1 - 0.014 14.9 3.9 0.016 14.7 1.6 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Reo_sigmaC PF04582.7 EGO58293.1 - 0.015 14.5 28.6 0.018 14.2 2.1 3.6 3 1 0 3 3 3 0 Reovirus sigma C capsid protein bZIP_1 PF00170.16 EGO58293.1 - 1.4 8.9 62.7 0.54 10.2 0.8 10.6 6 3 6 13 13 13 0 bZIP transcription factor Baculo_PEP_C PF04513.7 EGO58293.1 - 1.9 8.3 34.6 1.2 8.9 0.4 4.9 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus FYVE PF01363.16 EGO58293.1 - 3.6 7.5 11.0 44 4.0 7.7 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_4 PF13894.1 EGO58293.1 - 6.2 7.3 8.4 7 7.2 0.1 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger Myb_DNA-binding PF00249.26 EGO58294.1 - 7.6e-09 35.4 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGO58294.1 - 0.0092 16.0 0.1 0.021 14.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pet20 PF08692.5 EGO58294.1 - 0.24 11.3 4.5 0.068 13.0 0.5 2.1 2 0 0 2 2 2 0 Mitochondrial protein Pet20 XPC-binding PF09280.6 EGO58295.1 - 2.7e-24 84.3 11.9 4.9e-24 83.5 8.3 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EGO58295.1 - 1e-20 72.8 0.9 1.6e-20 72.2 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EGO58295.1 - 4e-16 58.2 2.7 4.1e-08 32.8 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EGO58295.1 - 4.3e-11 42.3 0.5 9.1e-11 41.3 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGO58295.1 - 0.0021 18.2 0.0 0.0052 16.9 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EGO58295.1 - 0.0052 16.6 0.1 0.016 15.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGO58295.1 - 0.014 15.6 0.1 0.032 14.4 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain UBA_3 PF09288.5 EGO58295.1 - 0.032 13.8 0.0 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Pneumo_att_G PF05539.6 EGO58295.1 - 0.24 10.7 4.9 0.34 10.2 3.4 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DIOX_N PF14226.1 EGO58298.1 - 1.7e-05 25.2 0.0 4.8e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGO58298.1 - 0.00012 22.2 0.0 0.00023 21.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Kelch_6 PF13964.1 EGO58299.1 - 0.053 13.7 0.6 46 4.4 0.0 3.6 3 0 0 3 3 3 0 Kelch motif ABC2_membrane_5 PF13346.1 EGO58299.1 - 1.2 8.3 14.7 0.19 11.0 5.8 2.3 1 1 2 3 3 3 0 ABC-2 family transporter protein Peptidase_M14 PF00246.19 EGO58301.1 - 2.2e-77 260.4 0.0 2.7e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EGO58301.1 - 8.9e-08 31.6 0.0 1.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase activation peptide Zn_clus PF00172.13 EGO58302.1 - 5.9e-08 32.4 13.2 1.1e-07 31.6 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RdRP PF05183.7 EGO58303.1 - 5.4e-117 391.8 0.0 7.6e-117 391.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF3602 PF12223.3 EGO58304.1 - 0.0082 16.5 0.8 0.0082 16.5 0.5 2.2 1 1 2 3 3 3 1 Protein of unknown function (DUF3602) Asp PF00026.18 EGO58306.1 - 5.8e-37 127.6 5.9 1e-23 84.0 0.3 3.1 3 0 0 3 3 3 3 Eukaryotic aspartyl protease TAXi_C PF14541.1 EGO58306.1 - 0.001 18.6 0.7 0.0018 17.8 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal E1-E2_ATPase PF00122.15 EGO58308.1 - 4.9e-48 163.1 6.7 8.1e-48 162.4 4.7 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGO58308.1 - 1.8e-25 90.6 0.0 3.1e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGO58308.1 - 1.8e-13 51.0 0.0 4e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGO58308.1 - 0.00019 21.1 0.1 0.1 12.1 0.0 2.6 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EGO58308.1 - 0.14 11.4 0.9 13 5.0 0.0 2.7 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.1 EGO58308.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Nramp PF01566.13 EGO58309.1 - 7.4e-92 307.8 20.1 1.1e-91 307.2 13.9 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Phtf-FEM1B_bdg PF12129.3 EGO58309.1 - 0.34 10.2 1.7 1 8.6 0.2 2.2 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Med22 PF06179.7 EGO58310.1 - 2.2e-06 27.6 0.0 3.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PseudoU_synth_1 PF01416.15 EGO58311.1 - 2.1e-24 85.9 0.0 4.6e-11 43.0 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.4 EGO58311.1 - 0.073 12.5 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) HET PF06985.6 EGO58312.1 - 1.8e-36 125.3 4.0 3.2e-36 124.5 2.8 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ATP_transf PF09830.4 EGO58316.1 - 1.3e-20 72.9 0.0 3.5e-20 71.5 0.0 1.8 2 0 0 2 2 2 1 ATP adenylyltransferase HIT PF01230.18 EGO58316.1 - 0.014 15.8 0.1 0.026 15.0 0.1 1.4 1 0 0 1 1 1 0 HIT domain CpeT PF06206.6 EGO58316.1 - 0.019 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) Scs3p PF10261.4 EGO58317.1 - 6.5e-71 238.1 2.6 8.4e-71 237.7 1.8 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Pectate_lyase_3 PF12708.2 EGO58318.1 - 1.7e-91 306.3 14.4 3.3e-73 246.5 3.8 3.1 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EGO58318.1 - 7.5e-07 28.5 2.3 0.0033 16.8 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 EGO58318.1 - 0.00028 20.6 6.6 0.00028 20.6 4.6 2.1 2 1 0 2 2 2 1 Right handed beta helix region NosD PF05048.8 EGO58318.1 - 0.004 16.3 4.8 0.004 16.3 3.4 1.7 2 0 0 2 2 2 1 Periplasmic copper-binding protein (NosD) WD40 PF00400.27 EGO58319.1 - 8e-44 146.0 16.7 1.5e-09 37.4 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EGO58319.1 - 3.5e-11 42.6 0.2 6.6e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO58319.1 - 6.2e-09 35.2 0.1 1.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EGO58319.1 - 8e-07 27.5 1.6 0.081 11.0 0.0 3.8 2 1 1 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EGO58319.1 - 7.9e-05 22.2 0.1 0.00038 19.9 0.1 2.1 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 EGO58319.1 - 0.0064 14.8 0.1 0.013 13.8 0.1 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EGO58319.1 - 0.014 14.1 1.1 5.3 5.6 0.0 3.2 1 1 1 3 3 3 0 Nup133 N terminal like DbpA PF03880.10 EGO58320.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 DbpA RNA binding domain Glyco_hydro_61 PF03443.9 EGO58321.1 - 6e-73 245.2 0.0 7.8e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SLAC1 PF03595.12 EGO58323.1 - 1.2e-85 287.1 38.2 1.3e-85 286.9 26.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel RINGv PF12906.2 EGO58324.1 - 8.4e-16 57.7 10.3 1.4e-15 57.0 7.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EGO58324.1 - 0.1 12.4 9.0 0.18 11.6 6.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 EGO58324.1 - 8.4 6.0 7.4 15 5.2 5.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HeLo PF14479.1 EGO58326.1 - 3.5e-08 33.4 1.9 0.00053 19.7 0.1 3.0 2 1 1 3 3 3 2 Prion-inhibition and propagation PIP5K PF01504.13 EGO58327.1 - 3.4e-29 101.7 0.0 5.1e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cofilin_ADF PF00241.15 EGO58327.1 - 2.1e-20 72.9 0.0 1.6e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein HET PF06985.6 EGO58328.1 - 6.2e-25 87.9 0.0 1e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GPS PF01825.16 EGO58329.1 - 1.3 9.1 4.3 2.7 8.1 3.0 1.5 1 0 0 1 1 1 0 Latrophilin/CL-1-like GPS domain Glyco_hydro_10 PF00331.15 EGO58330.1 - 1.6e-87 293.5 0.0 1.8e-87 293.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 GHL15 PF14885.1 EGO58330.1 - 0.036 14.2 0.0 0.79 9.9 0.0 2.6 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase family 15 LANC_like PF05147.8 EGO58331.1 - 1.1e-28 99.9 0.0 9.5e-27 93.4 0.0 2.0 2 0 0 2 2 2 2 Lanthionine synthetase C-like protein Hydrophobin_2 PF06766.6 EGO58333.1 - 5.6e-27 93.2 8.7 7.9e-27 92.7 6.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin FAD_binding_8 PF08022.7 EGO58335.1 - 8.9e-17 60.8 0.0 2e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EGO58335.1 - 5.7e-13 49.0 0.0 1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EGO58335.1 - 3.8e-12 46.3 13.0 3.8e-12 46.3 9.0 2.1 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGO58335.1 - 0.018 15.1 0.0 0.053 13.6 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain tRNA-synt_1d PF00750.14 EGO58336.1 - 1.1e-78 264.5 3.5 2.1e-78 263.6 2.5 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EGO58336.1 - 4.8e-30 103.9 0.1 1.2e-29 102.6 0.0 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EGO58336.1 - 3.6e-05 24.2 0.0 9.2e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain p450 PF00067.17 EGO58338.1 - 8e-52 176.2 0.0 1.9e-51 175.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EGO58339.1 - 7.1e-29 100.0 1.8 1.1e-28 99.4 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGO58339.1 - 3.7e-14 52.3 0.1 7.4e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like An_peroxidase PF03098.10 EGO58341.1 - 2.2e-125 419.0 0.0 2.6e-125 418.8 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase F-box-like PF12937.2 EGO58342.1 - 0.012 15.2 0.0 0.12 12.1 0.0 2.6 3 1 0 3 3 3 0 F-box-like Rieske PF00355.21 EGO58344.1 - 0.038 13.5 1.1 0.066 12.7 0.0 2.0 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain NOA36 PF06524.7 EGO58345.1 - 0.014 14.6 5.7 0.016 14.5 3.9 1.1 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.9 EGO58345.1 - 5.3 6.5 10.4 7.4 6.0 7.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PALP PF00291.20 EGO58352.1 - 3.6e-59 200.5 0.0 4.6e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EGO58352.1 - 2.2e-10 40.1 0.0 1.2e-07 31.4 0.0 3.0 3 0 0 3 3 3 2 CBS domain SRPRB PF09439.5 EGO58353.1 - 1.7e-22 79.5 0.0 4e-20 71.7 0.0 3.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EGO58353.1 - 4.1e-05 23.1 0.0 0.00071 19.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EGO58353.1 - 5.5e-05 23.2 0.2 0.00012 22.1 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 EGO58353.1 - 0.002 18.0 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EGO58353.1 - 0.0028 16.7 0.2 0.0047 16.0 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin DUF258 PF03193.11 EGO58353.1 - 0.023 13.9 0.7 0.13 11.4 0.5 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Arf PF00025.16 EGO58353.1 - 0.031 13.5 0.0 0.67 9.1 0.0 2.4 2 1 0 2 2 2 0 ADP-ribosylation factor family ABC_tran PF00005.22 EGO58353.1 - 0.088 13.1 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EGO58353.1 - 0.099 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGO58353.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ank PF00023.25 EGO58354.1 - 1.8e-37 125.2 0.2 9.7e-09 34.6 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat zf-DHHC PF01529.15 EGO58354.1 - 2.1e-37 128.2 9.3 2.1e-37 128.2 6.4 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.2 EGO58354.1 - 9.8e-35 118.7 0.1 5.9e-17 61.7 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGO58354.1 - 4.3e-27 93.5 0.3 1.6e-08 34.4 0.0 5.2 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGO58354.1 - 4.1e-24 84.4 5.3 8.5e-08 32.5 0.0 4.7 1 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO58354.1 - 6.7e-24 81.5 0.6 2.4e-07 30.3 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat stn_TNFRSF12A PF12191.3 EGO58354.1 - 1.2 9.2 4.4 0.55 10.2 0.6 2.3 3 0 0 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain FtsX PF02687.16 EGO58354.1 - 4 7.2 14.3 0.38 10.5 6.0 2.2 2 0 0 2 2 2 0 FtsX-like permease family DLH PF01738.13 EGO58356.1 - 3.1e-24 85.4 0.0 3.9e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGO58356.1 - 0.00013 21.7 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family CcmH PF03918.9 EGO58357.1 - 0.072 12.0 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF641 PF04859.7 EGO58357.1 - 0.13 12.0 1.0 0.23 11.1 0.7 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) NicO PF03824.11 EGO58360.1 - 7e-64 215.8 7.5 9e-64 215.4 5.2 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein DUF1191 PF06697.7 EGO58360.1 - 0.025 13.4 0.4 0.33 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) Glyco_tranf_2_3 PF13641.1 EGO58361.1 - 1.6e-29 103.3 0.3 2.1e-29 102.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGO58361.1 - 5.2e-22 78.3 0.1 7.8e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 EGO58361.1 - 1.3e-21 77.1 0.9 1.3e-21 77.1 0.6 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EGO58361.1 - 1.5e-19 69.9 0.0 2.3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 EGO58361.1 - 6.1e-06 24.8 3.2 0.00028 19.3 0.4 2.3 2 1 0 2 2 2 2 Cellulose synthase Glyco_tranf_2_2 PF10111.4 EGO58361.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_hydro_12 PF01670.11 EGO58362.1 - 4e-13 49.4 0.1 1e-12 48.0 0.2 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 UDPG_MGDP_dh_N PF03721.9 EGO58363.1 - 6.7e-49 165.7 0.1 1.6e-33 115.6 0.0 2.5 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EGO58363.1 - 1.7e-25 89.1 0.0 6.1e-19 68.1 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EGO58363.1 - 8.6e-25 86.7 0.0 1.9e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.10 EGO58363.1 - 0.0018 18.1 0.1 0.074 12.8 0.1 3.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EGO58363.1 - 0.0085 15.8 0.3 0.12 12.0 0.2 2.7 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3439 PF11921.3 EGO58366.1 - 0.018 14.7 9.4 0.043 13.5 6.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 EGO58366.1 - 1.5 6.5 6.3 2.2 5.9 4.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Acyl_transf_3 PF01757.17 EGO58367.1 - 2.7e-31 108.6 37.2 3.6e-31 108.2 25.8 1.2 1 0 0 1 1 1 1 Acyltransferase family Gly_transf_sug PF04488.10 EGO58368.1 - 0.0036 17.6 0.1 0.017 15.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Bud13 PF09736.4 EGO58368.1 - 0.81 9.9 10.4 1.3 9.2 7.2 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex FSH1 PF03959.8 EGO58369.1 - 4.3e-26 91.6 0.0 5e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EGO58369.1 - 2.1e-06 27.7 0.1 0.0001 22.2 0.1 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Vac7 PF12751.2 EGO58370.1 - 0.12 11.2 0.1 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 zf-PHD-like PF15446.1 EGO58372.1 - 2.7 7.2 7.4 0.56 9.4 1.6 1.9 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain DUF2763 PF10961.3 EGO58372.1 - 4.2 7.8 9.3 18 5.8 6.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) DUF2036 PF09724.4 EGO58373.1 - 0.022 13.9 0.0 0.025 13.7 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2036) Cystatin PF00031.16 EGO58373.1 - 0.43 10.7 2.7 20 5.4 0.0 2.2 2 0 0 2 2 2 0 Cystatin domain LacI PF00356.16 EGO58379.1 - 0.086 12.4 0.5 0.21 11.2 0.3 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Dmrt1 PF12374.3 EGO58383.1 - 0.0039 17.5 1.2 0.14 12.5 0.3 2.1 2 0 0 2 2 2 2 Double-sex mab3 related transcription factor 1 Binary_toxB PF03495.9 EGO58393.1 - 0.0056 15.3 0.6 0.0068 15.0 0.4 1.0 1 0 0 1 1 1 1 Clostridial binary toxin B/anthrax toxin PA DUF1127 PF06568.6 EGO58397.1 - 0.0077 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1127) Myosin_tail_1 PF01576.14 EGO58397.1 - 0.012 13.4 1.2 0.016 13.0 0.8 1.0 1 0 0 1 1 1 0 Myosin tail Filament PF00038.16 EGO58397.1 - 0.012 15.0 0.6 0.019 14.4 0.4 1.2 1 0 0 1 1 1 0 Intermediate filament protein FlxA PF14282.1 EGO58397.1 - 0.022 14.7 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF3450 PF11932.3 EGO58397.1 - 0.024 13.9 0.2 0.035 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) C1_1 PF00130.17 EGO58400.1 - 0.07 12.8 2.1 0.11 12.1 1.5 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NUDIX PF00293.23 EGO58401.1 - 5.6e-14 51.9 0.2 1.6e-13 50.4 0.1 1.7 2 0 0 2 2 2 1 NUDIX domain NUDE_C PF04880.8 EGO58403.1 - 5.3e-11 43.1 27.0 5.3e-11 43.1 18.7 4.5 2 1 1 4 4 2 1 NUDE protein, C-terminal conserved region IncA PF04156.9 EGO58403.1 - 0.0052 16.3 40.2 0.012 15.1 16.3 2.6 2 1 1 3 3 3 2 IncA protein WEMBL PF05701.6 EGO58403.1 - 0.0053 15.2 29.9 0.0085 14.5 20.7 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF904 PF06005.7 EGO58403.1 - 0.0077 16.5 8.2 0.0077 16.5 5.7 3.9 2 1 1 3 3 2 1 Protein of unknown function (DUF904) Tropomyosin_1 PF12718.2 EGO58403.1 - 0.08 12.7 39.8 0.77 9.5 18.3 3.7 2 1 1 3 3 3 0 Tropomyosin like DUF3584 PF12128.3 EGO58403.1 - 0.12 9.6 24.6 0.2 8.9 17.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.4 EGO58403.1 - 0.14 11.9 38.9 0.54 10.1 11.8 3.7 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Chibby PF14645.1 EGO58403.1 - 0.15 11.9 15.6 0.072 12.9 0.6 3.3 2 1 1 3 3 3 0 Chibby family Filament PF00038.16 EGO58403.1 - 0.17 11.3 33.0 0.5 9.7 10.9 2.6 2 1 1 3 3 3 0 Intermediate filament protein AAA_13 PF13166.1 EGO58403.1 - 0.6 8.5 24.1 1.1 7.6 16.7 1.3 1 0 0 1 1 1 0 AAA domain DUF641 PF04859.7 EGO58403.1 - 0.62 9.8 22.3 5 6.8 1.4 4.2 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) IFT57 PF10498.4 EGO58403.1 - 1.4 7.6 23.1 0.028 13.1 8.6 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 NACHT PF05729.7 EGO58404.1 - 2.3e-06 27.3 0.0 6.3e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain SR-25 PF10500.4 EGO58404.1 - 0.0014 18.1 10.0 0.0025 17.3 6.9 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DNA_pol3_alpha PF07733.7 EGO58404.1 - 0.053 11.9 0.0 0.096 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit NB-ARC PF00931.17 EGO58404.1 - 0.18 10.5 0.0 14 4.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Dicty_REP PF05086.7 EGO58404.1 - 0.81 7.3 6.8 1.5 6.4 4.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.27 EGO58405.1 - 3.3e-56 185.2 25.4 6e-10 38.6 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EGO58405.1 - 1.3e-12 46.6 3.9 0.00015 20.0 0.0 4.2 2 1 2 4 4 4 4 Nucleoporin Nup120/160 F-box-like PF12937.2 EGO58405.1 - 1.2e-09 37.6 0.3 4.3e-09 35.9 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO58405.1 - 8.7e-09 34.8 0.1 6.6e-08 32.0 0.0 2.3 1 1 1 2 2 2 1 F-box domain YmzC PF14157.1 EGO58405.1 - 0.068 12.9 0.0 4.2 7.2 0.0 3.1 3 0 0 3 3 3 0 YmzC-like protein Mito_carr PF00153.22 EGO58407.1 - 4.4e-71 234.6 5.4 1.2e-22 79.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl_transf_3 PF01757.17 EGO58410.1 - 9.4e-21 74.0 21.1 2.8e-20 72.4 14.6 2.1 1 1 0 1 1 1 1 Acyltransferase family F-box-like PF12937.2 EGO58411.1 - 2.5e-05 23.9 0.5 8.1e-05 22.2 0.4 2.0 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EGO58411.1 - 0.43 10.3 2.2 0.78 9.4 0.1 2.3 3 0 0 3 3 3 0 F-box-like domain SpecificRecomb PF10136.4 EGO58413.1 - 0.18 9.8 1.9 0.39 8.7 1.3 1.5 1 0 0 1 1 1 0 Site-specific recombinase Mnd1 PF03962.10 EGO58415.1 - 0.00047 19.8 3.3 0.00089 18.9 2.3 1.4 1 0 0 1 1 1 1 Mnd1 family HAUS-augmin3 PF14932.1 EGO58415.1 - 0.0026 16.9 3.0 0.038 13.1 0.1 2.1 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 Not3 PF04065.10 EGO58415.1 - 0.011 15.0 4.0 1.4 8.1 0.2 3.0 1 1 2 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component DAHP_synth_2 PF01474.11 EGO58415.1 - 0.016 13.6 0.1 0.1 10.9 0.0 2.0 2 0 0 2 2 2 0 Class-II DAHP synthetase family Hydantoinase_A PF01968.13 EGO58415.1 - 0.095 11.7 0.0 0.31 10.1 0.0 1.7 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase LrgB PF04172.11 EGO58416.1 - 1.7e-12 46.9 15.7 3.5e-07 29.6 1.4 2.6 3 0 0 3 3 3 2 LrgB-like family Rotamase PF00639.16 EGO58417.1 - 4.3e-23 81.8 0.0 7.2e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EGO58417.1 - 1.7e-17 63.7 0.0 2.3e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EGO58417.1 - 1.3e-09 37.6 1.2 2.9e-09 36.6 0.9 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EGO58417.1 - 1.8e-06 28.5 0.0 2.4e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Hex_IIIa PF02455.11 EGO58417.1 - 0.036 12.7 0.2 0.04 12.6 0.1 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) MAM PF00629.18 EGO58417.1 - 0.038 13.7 1.4 0.11 12.2 0.6 1.9 1 1 0 1 1 1 0 MAM domain RNA_POL_M_15KD PF02150.11 EGO58418.1 - 4.6e-09 35.8 3.3 4.6e-09 35.8 2.3 2.2 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit DUF1462 PF07315.6 EGO58418.1 - 0.031 14.2 0.1 0.071 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) FYVE PF01363.16 EGO58418.1 - 1.3 9.0 5.8 5.7 6.9 0.6 2.3 2 0 0 2 2 2 0 FYVE zinc finger Nudix_N_2 PF14803.1 EGO58418.1 - 4.4 7.0 8.7 0.21 11.3 0.4 2.3 2 0 0 2 2 2 0 Nudix N-terminal DZR PF12773.2 EGO58418.1 - 5.8 6.8 9.7 0.29 10.9 1.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon Ribosomal_L14 PF00238.14 EGO58419.1 - 4.4e-45 152.3 4.0 4.9e-45 152.2 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SET PF00856.23 EGO58420.1 - 4.4e-09 36.8 0.3 1.6e-08 35.0 0.0 2.1 2 0 0 2 2 2 1 SET domain DUF2358 PF10184.4 EGO58420.1 - 0.089 12.7 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) zf-C3HC4_3 PF13920.1 EGO58420.1 - 0.51 10.0 6.5 1.4 8.6 1.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) BTB PF00651.26 EGO58421.1 - 0.0023 17.8 0.0 0.0053 16.7 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Epimerase PF01370.16 EGO58422.1 - 9.1e-22 77.6 0.1 2.4e-20 72.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO58422.1 - 7.6e-15 55.3 0.1 9.5e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGO58422.1 - 1.1e-11 44.0 0.0 1.6e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGO58422.1 - 6.1e-06 25.3 0.5 1.1e-05 24.4 0.3 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGO58422.1 - 1.8e-05 23.8 0.3 5.3e-05 22.2 0.2 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EGO58422.1 - 0.00011 21.6 0.0 0.00019 20.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EGO58422.1 - 0.0017 18.3 1.8 0.0092 15.9 0.3 2.5 2 1 0 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 EGO58422.1 - 0.0022 18.2 0.0 0.0053 17.0 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EGO58422.1 - 0.0031 17.4 0.0 0.0074 16.2 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DFP PF04127.10 EGO58422.1 - 0.0043 16.6 0.1 0.0075 15.8 0.1 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Peptidase_C54 PF03416.14 EGO58422.1 - 0.03 13.4 0.1 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C54 Ldh_1_N PF00056.18 EGO58422.1 - 0.14 11.9 0.1 0.27 11.0 0.1 1.5 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Topo-VIb_trans PF09239.6 EGO58424.1 - 0.12 11.9 0.2 0.33 10.4 0.1 1.7 2 0 0 2 2 2 0 Topoisomerase VI B subunit, transducer DUF3391 PF11871.3 EGO58424.1 - 3.1 8.0 7.8 3.2 7.9 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3391) DUF2937 PF11157.3 EGO58426.1 - 0.25 10.6 3.3 0.15 11.3 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF3432 PF11914.3 EGO58427.1 - 0.08 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) YdjO PF14169.1 EGO58430.1 - 0.11 11.9 0.4 2.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Cold-inducible protein YdjO DUF3439 PF11921.3 EGO58432.1 - 0.23 11.2 5.9 0.77 9.5 4.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Bravo_FIGEY PF13882.1 EGO58432.1 - 6.4 7.7 11.7 5.6 7.9 5.8 2.7 2 0 0 2 2 2 0 Bravo-like intracellular region NACHT PF05729.7 EGO58435.1 - 1e-12 48.0 0.4 1e-12 48.0 0.3 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EGO58435.1 - 2.1e-08 34.3 1.5 5.4e-08 33.0 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGO58435.1 - 2.2e-06 27.8 0.4 9.4e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EGO58435.1 - 0.00017 20.6 1.1 0.042 12.8 0.2 2.6 1 1 1 2 2 2 2 KAP family P-loop domain AAA_18 PF13238.1 EGO58435.1 - 0.0017 18.6 0.0 0.012 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EGO58435.1 - 0.0018 18.5 0.2 0.021 15.1 0.0 2.8 2 1 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 EGO58435.1 - 0.0026 18.5 0.3 0.019 15.7 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGO58435.1 - 0.0071 15.8 0.0 0.024 14.0 0.0 2.0 1 1 0 1 1 1 1 AAA-like domain AAA_14 PF13173.1 EGO58435.1 - 0.013 15.4 0.3 1.8 8.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 EGO58435.1 - 0.031 14.4 0.0 0.23 11.6 0.0 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EGO58435.1 - 0.053 13.6 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase T6SS_Vgr PF13296.1 EGO58436.1 - 0.066 13.0 1.2 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 Putative type VI secretion system Rhs element Vgr ACC_central PF08326.7 EGO58438.1 - 1.1e-264 879.9 0.0 1.4e-264 879.6 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EGO58438.1 - 5.9e-177 588.9 0.0 8.3e-177 588.4 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EGO58438.1 - 4.7e-52 176.3 0.0 1.2e-51 174.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EGO58438.1 - 1.1e-23 83.4 0.1 2.2e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGO58438.1 - 4.5e-21 74.8 0.0 6.1e-19 67.9 0.0 3.4 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EGO58438.1 - 2.3e-16 59.1 0.1 5e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EGO58438.1 - 1e-09 38.3 0.0 2.7e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGO58438.1 - 0.00016 21.0 0.0 0.00034 20.0 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EGO58438.1 - 0.0049 16.7 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EGO58438.1 - 0.056 12.7 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EGO58438.1 - 0.059 13.0 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like HlyD_2 PF12700.2 EGO58438.1 - 0.2 10.7 0.0 0.4 9.7 0.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein Lipoprotein_21 PF14041.1 EGO58441.1 - 0.051 13.5 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 LppP/LprE lipoprotein Flp_Fap PF04964.9 EGO58443.1 - 0.059 12.9 0.9 0.12 12.0 0.6 1.5 1 0 0 1 1 1 0 Flp/Fap pilin component AA_permease PF00324.16 EGO58446.1 - 4.7e-109 364.8 37.6 5.8e-109 364.5 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO58446.1 - 3.4e-33 114.8 43.2 4.2e-33 114.5 29.9 1.1 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_6 PF12697.2 EGO58448.1 - 8.9e-26 91.1 0.0 1.1e-25 90.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO58448.1 - 3.7e-10 39.7 0.0 9.4e-10 38.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO58448.1 - 6e-07 29.2 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EGO58448.1 - 1.5e-06 27.9 0.0 0.00029 20.4 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold HET PF06985.6 EGO58449.1 - 2.3e-21 76.4 0.0 1.1e-20 74.2 0.0 2.1 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Myb_DNA-bind_6 PF13921.1 EGO58450.1 - 0.00039 20.4 0.1 0.027 14.5 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain stn_TNFRSF12A PF12191.3 EGO58451.1 - 0.026 14.5 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF1628 PF07790.6 EGO58451.1 - 1.7 9.4 6.3 0.46 11.2 0.6 2.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1628) PRCC PF10253.4 EGO58452.1 - 0.093 13.4 0.4 0.093 13.4 0.3 1.5 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting DUF3530 PF12048.3 EGO58452.1 - 0.67 8.8 5.2 1.1 8.1 3.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3530) F-box-like PF12937.2 EGO58457.1 - 0.0056 16.3 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like RE_HaeII PF09554.5 EGO58457.1 - 0.047 12.6 0.1 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 HaeII restriction endonuclease Metallophos PF00149.23 EGO58459.1 - 2.1e-13 50.1 0.1 4.6e-12 45.7 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGO58459.1 - 6e-11 42.4 0.0 9.5e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MPC PF03650.8 EGO58460.1 - 1.8e-32 111.7 0.2 2.2e-32 111.4 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) EutH PF04346.7 EGO58460.1 - 0.039 12.9 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH IcmF-related PF06761.7 EGO58461.1 - 0.022 14.0 0.2 0.031 13.5 0.1 1.2 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing FdhD-NarQ PF02634.10 EGO58461.1 - 0.028 13.8 0.5 0.039 13.4 0.4 1.1 1 0 0 1 1 1 0 FdhD/NarQ family Dicty_REP PF05086.7 EGO58461.1 - 0.31 8.7 2.9 0.3 8.7 2.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.8 EGO58461.1 - 0.42 10.4 4.8 0.45 10.3 3.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 EGO58461.1 - 8.2 5.7 15.5 10 5.4 10.8 1.1 1 0 0 1 1 1 0 Vta1 like Rab5-bind PF09311.6 EGO58462.1 - 0.005 16.7 0.2 0.005 16.7 0.1 2.1 2 0 0 2 2 2 1 Rabaptin-like protein Kinesin-relat_1 PF12711.2 EGO58462.1 - 0.16 12.3 4.5 0.34 11.3 3.1 1.4 1 0 0 1 1 1 0 Kinesin motor DUF904 PF06005.7 EGO58462.1 - 0.21 11.9 7.7 0.34 11.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 EGO58462.1 - 5.1 6.6 6.6 2.8 7.5 0.1 2.4 1 1 1 2 2 2 0 Septum formation initiator Catalase PF00199.14 EGO58463.1 - 1.2e-162 541.0 0.3 1.8e-162 540.4 0.2 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGO58463.1 - 5.2e-22 77.4 0.0 1e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EGO58463.1 - 1.3e-11 44.2 0.1 2.8e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EGO58463.1 - 1.4e-05 24.4 0.0 2.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase SET PF00856.23 EGO58464.1 - 1.3e-05 25.5 0.0 5.5e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 SET domain DUF2599 PF10783.4 EGO58465.1 - 0.038 14.6 0.1 0.063 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2599) MAP65_ASE1 PF03999.7 EGO58466.1 - 0.4 9.2 4.6 1.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) DUF1308 PF07000.6 EGO58467.1 - 1.9e-18 66.2 0.0 2.7e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Abhydrolase_5 PF12695.2 EGO58470.1 - 3.7e-07 29.9 0.0 5.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGO58470.1 - 4.9e-06 26.1 0.0 8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 EGO58470.1 - 0.0043 16.3 1.0 0.028 13.6 0.1 2.1 1 1 1 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.15 EGO58470.1 - 0.037 13.4 0.3 2.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Putative esterase Abhydrolase_1 PF00561.15 EGO58470.1 - 0.043 13.3 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EGO58470.1 - 0.094 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EGO58470.1 - 0.11 12.3 0.2 0.2 11.5 0.1 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family adh_short PF00106.20 EGO58471.1 - 2.4e-18 66.6 0.1 3.3e-18 66.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO58471.1 - 2.5e-08 33.7 0.3 3.4e-08 33.3 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGO58471.1 - 0.0016 18.2 0.3 0.0039 16.9 0.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EGO58471.1 - 0.0028 16.6 0.1 0.0081 15.0 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGO58471.1 - 0.034 13.5 0.0 0.1 11.9 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGO58471.1 - 0.035 13.8 0.2 0.071 12.9 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EGO58471.1 - 0.055 13.5 0.1 0.13 12.3 0.1 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Met_synt_B12 PF02965.12 EGO58471.1 - 0.081 12.1 0.2 0.24 10.5 0.0 1.8 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain Glyco_hydro_35 PF01301.14 EGO58472.1 - 9.4e-18 64.6 0.0 1.1e-17 64.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 EHN PF06441.7 EGO58473.1 - 9.4e-34 115.7 0.1 1.6e-33 114.9 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EGO58473.1 - 3.3e-06 27.1 0.1 9.5e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family tRNA_bind_2 PF13725.1 EGO58473.1 - 0.079 13.0 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Possible tRNA binding domain Peptidase_M24 PF00557.19 EGO58474.1 - 8.4e-57 192.0 0.1 3.9e-56 189.9 0.1 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.11 EGO58474.1 - 1.2e-25 89.4 0.0 2.6e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Aldo_ket_red PF00248.16 EGO58475.1 - 5.1e-58 196.1 0.0 6.3e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CBM_21 PF03370.8 EGO58478.1 - 6.5e-36 122.7 0.2 1.2e-35 121.9 0.2 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit DUF221 PF02714.10 EGO58484.1 - 1.4e-108 362.6 13.0 2.8e-108 361.6 9.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGO58484.1 - 2.7e-42 143.9 1.7 2.7e-42 143.9 1.2 2.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EGO58484.1 - 7.6e-23 80.2 0.0 2.1e-22 78.7 0.0 1.7 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EGO58484.1 - 5.2e-10 39.6 0.0 5.7e-09 36.3 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EGO58484.1 - 0.0042 17.0 0.0 0.047 13.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO58484.1 - 0.023 14.3 0.0 0.24 11.0 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO58484.1 - 0.16 11.7 0.0 0.62 9.9 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2135 PF09906.4 EGO58485.1 - 0.02 14.8 1.2 0.6 10.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2135) SR-25 PF10500.4 EGO58485.1 - 2.8 7.3 9.7 3.9 6.8 6.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cyclin PF08613.6 EGO58488.1 - 2.4e-46 157.8 0.0 3.9e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EGO58488.1 - 0.0071 15.9 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain TPP_enzyme_N PF02776.13 EGO58489.1 - 8.1e-38 129.5 0.4 5.2e-37 126.9 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGO58489.1 - 9.5e-23 80.4 0.0 2e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGO58489.1 - 4.3e-22 78.3 0.0 1.9e-21 76.2 0.0 2.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain DUF2203 PF09969.4 EGO58489.1 - 0.08 13.1 1.8 8.9 6.5 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) AAA_23 PF13476.1 EGO58489.1 - 0.87 9.8 4.7 1.3 9.3 3.2 1.2 1 0 0 1 1 1 0 AAA domain CHZ PF09649.5 EGO58490.1 - 0.019 14.1 0.2 0.047 12.9 0.2 1.7 1 0 0 1 1 1 0 Histone chaperone domain CHZ ADH_zinc_N PF00107.21 EGO58491.1 - 1.2e-15 57.2 0.3 2.4e-15 56.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO58491.1 - 2.2e-14 54.4 0.0 7.3e-14 52.7 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO58491.1 - 5.9e-05 22.7 0.0 0.00027 20.6 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 EGO58491.1 - 0.0063 15.9 0.0 0.0089 15.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.16 EGO58491.1 - 0.043 13.4 0.6 0.07 12.6 0.4 1.4 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Semialdhyde_dh PF01118.19 EGO58491.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RIO1 PF01163.17 EGO58492.1 - 2.8e-71 238.7 0.4 6.3e-71 237.6 0.0 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EGO58492.1 - 3.2e-05 23.8 0.1 0.14 11.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGO58492.1 - 0.00032 19.8 0.1 0.0043 16.1 0.1 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1910 PF08928.5 EGO58492.1 - 0.43 10.6 6.4 1.4 9.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1910) CDC45 PF02724.9 EGO58492.1 - 4.7 5.1 17.6 7.6 4.4 12.2 1.4 1 0 0 1 1 1 0 CDC45-like protein APG17 PF04108.7 EGO58493.1 - 2.3e-119 398.8 0.0 2.6e-119 398.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 AF0941-like PF14591.1 EGO58493.1 - 0.13 12.3 1.7 0.72 9.9 0.1 2.6 2 2 0 2 2 2 0 AF0941-like HrpE PF06188.7 EGO58493.1 - 0.13 11.9 1.8 0.69 9.6 0.0 2.8 3 1 1 4 4 4 0 HrpE/YscL/FliH and V-type ATPase subunit E Flavokinase PF01687.12 EGO58498.1 - 3.3e-13 49.6 0.0 5.3e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase ERG4_ERG24 PF01222.12 EGO58500.1 - 1.7e-204 679.2 3.3 2e-204 679.0 2.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EGO58500.1 - 0.00011 21.5 0.5 0.00036 19.9 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.10 EGO58501.1 - 7.2e-12 44.8 0.0 1.2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 EGO58501.1 - 1.1e-06 28.0 8.5 3.9e-06 26.3 4.9 2.5 2 1 1 3 3 3 1 Autophagy-related protein 27 CIMR PF00878.13 EGO58501.1 - 1.5e-06 28.0 0.1 0.00017 21.3 0.0 2.4 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat CDC45 PF02724.9 EGO58501.1 - 0.46 8.4 5.6 0.65 7.9 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_61 PF03443.9 EGO58503.1 - 2.9e-60 203.7 0.1 4.2e-60 203.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EGO58503.1 - 1.2e-09 37.5 13.8 1.2e-09 37.5 9.6 3.1 2 1 0 2 2 2 1 Fungal cellulose binding domain NPCBM_assoc PF10633.4 EGO58503.1 - 0.04 13.9 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Zn_ribbon_2 PF12674.2 EGO58504.1 - 0.18 12.1 0.1 0.18 12.1 0.1 1.6 2 0 0 2 2 2 0 Putative zinc ribbon domain EGF_CA PF07645.10 EGO58506.1 - 0.46 10.5 3.7 1.3 9.0 0.3 2.3 2 0 0 2 2 2 0 Calcium-binding EGF domain ADH_N PF08240.7 EGO58508.1 - 1.6e-10 40.7 0.1 4.3e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO58508.1 - 5.4e-08 32.4 0.1 9.4e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Subtilosin_A PF11420.3 EGO58508.1 - 0.066 13.2 4.2 0.26 11.3 0.6 2.5 2 0 0 2 2 2 0 Bacteriocin subtilosin A Eno-Rase_NADH_b PF12242.3 EGO58508.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF721 PF05258.7 EGO58508.1 - 0.16 12.1 0.0 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF721) PAN_4 PF14295.1 EGO58509.1 - 2.5e-05 23.9 3.7 2.5e-05 23.9 2.6 2.0 2 0 0 2 2 2 1 PAN domain PAN_2 PF08276.6 EGO58509.1 - 0.034 13.9 1.3 0.034 13.9 0.9 2.0 2 0 0 2 2 2 0 PAN-like domain Glyco_hydro_3 PF00933.16 EGO58510.1 - 2.6e-91 305.7 0.0 4e-91 305.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO58510.1 - 3.2e-57 193.6 0.3 2.6e-56 190.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGO58510.1 - 2.3e-14 53.0 0.7 5e-14 52.0 0.5 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain APO_RNA-bind PF05634.6 EGO58512.1 - 0.068 12.3 0.3 0.17 11.0 0.0 1.8 2 0 0 2 2 2 0 APO RNA-binding COesterase PF00135.23 EGO58513.1 - 4.7e-81 273.1 2.2 6.7e-81 272.6 1.5 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO58513.1 - 1.8e-05 24.4 0.3 8.2e-05 22.2 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold 2Fe-2S_Ferredox PF11591.3 EGO58514.1 - 0.032 13.8 1.0 4 7.1 0.1 2.5 2 0 0 2 2 2 0 Ferredoxin chloroplastic transit peptide p450 PF00067.17 EGO58516.1 - 2.8e-24 85.4 0.0 4.3e-17 61.7 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 FAD_binding_4 PF01565.18 EGO58517.1 - 4.9e-27 94.0 0.2 1.3e-26 92.7 0.1 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGO58517.1 - 4.3e-05 23.3 1.3 8.5e-05 22.3 0.9 1.5 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 EGO58518.1 - 2e-32 112.3 0.6 3.2e-20 72.1 0.4 2.7 2 1 0 2 2 2 2 Cytochrome P450 IL32 PF15225.1 EGO58518.1 - 0.00097 19.0 0.3 0.005 16.7 0.1 2.1 2 0 0 2 2 2 1 Interleukin 32 Methyltransf_2 PF00891.13 EGO58519.1 - 4.8e-33 114.3 0.2 7.1e-33 113.7 0.0 1.4 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_18 PF12847.2 EGO58519.1 - 6.4e-06 26.7 0.0 1.8e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO58519.1 - 4.3e-05 23.1 0.0 8.1e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO58519.1 - 4.6e-05 23.7 0.0 0.0013 19.0 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 EGO58519.1 - 5.2e-05 22.6 0.0 9.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EGO58519.1 - 0.0064 16.9 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO58519.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EGO58519.1 - 0.017 14.8 0.0 0.086 12.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 EGO58519.1 - 0.042 12.8 0.0 0.068 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Receptor_IA-2 PF11548.3 EGO58519.1 - 0.057 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein-tyrosine phosphatase receptor IA-2 PS-DH PF14765.1 EGO58521.1 - 1.5e-69 234.4 0.2 2.7e-69 233.5 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 EGO58521.1 - 1.8e-69 234.0 0.1 1.8e-69 234.0 0.0 2.2 3 0 0 3 3 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EGO58521.1 - 2.3e-58 196.8 1.1 7.1e-58 195.2 0.4 2.2 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EGO58521.1 - 6.2e-56 190.0 0.5 1.2e-55 189.1 0.3 1.4 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EGO58521.1 - 2.9e-46 157.4 0.9 2.9e-46 157.4 0.6 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EGO58521.1 - 3e-36 123.8 0.0 2.2e-35 121.0 0.0 2.6 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EGO58521.1 - 4.1e-20 72.1 0.0 5.1e-19 68.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO58521.1 - 2.6e-16 59.7 0.0 1.9e-14 53.6 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO58521.1 - 1.2e-11 44.4 0.0 3.3e-11 42.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO58521.1 - 1.8e-10 41.1 0.0 1.2e-09 38.5 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EGO58521.1 - 2.3e-10 40.1 0.3 4.6e-08 32.6 0.1 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EGO58521.1 - 8.7e-10 39.1 0.0 9.1e-09 35.8 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain 3Beta_HSD PF01073.14 EGO58521.1 - 4.1e-07 28.9 0.0 7e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 EGO58521.1 - 5.9e-07 29.6 0.4 1.6e-06 28.2 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 EGO58521.1 - 3.2e-06 27.4 0.0 1.3e-05 25.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO58521.1 - 5.3e-06 25.7 0.0 1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.10 EGO58521.1 - 7.7e-05 21.7 0.0 0.00013 20.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_26 PF13659.1 EGO58521.1 - 0.00012 22.1 0.1 0.0013 18.7 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain ADH_N PF08240.7 EGO58521.1 - 0.00013 21.7 0.3 0.00027 20.6 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EGO58521.1 - 0.0006 18.8 0.1 0.0014 17.6 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EGO58521.1 - 0.0018 17.9 0.2 0.0045 16.6 0.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Epimerase PF01370.16 EGO58521.1 - 0.0096 15.3 0.0 0.031 13.7 0.0 1.9 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_8 PF05148.10 EGO58521.1 - 0.31 10.6 0.0 0.73 9.4 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase DNA_gyraseB_C PF00986.16 EGO58521.1 - 0.34 10.6 0.0 0.79 9.5 0.0 1.5 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus Glyco_trans_4_2 PF13477.1 EGO58521.1 - 0.51 10.1 0.0 20 5.0 0.0 2.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like AATase PF07247.7 EGO58522.1 - 6.3e-21 74.4 0.0 6.2e-17 61.3 0.0 2.1 2 0 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.15 EGO58522.1 - 2.1e-05 23.5 0.7 0.0031 16.3 0.1 2.3 2 0 0 2 2 2 2 Condensation domain MFS_1 PF07690.11 EGO58523.1 - 6.4e-40 136.9 50.7 8.4e-39 133.2 34.8 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGO58523.1 - 9.5e-13 47.2 12.4 9.5e-13 47.2 8.6 2.2 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 EGO58524.1 - 1.2e-05 24.3 0.1 2.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EGO58525.1 - 1.8e-17 63.7 0.1 5.5e-17 62.1 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EGO58525.1 - 6.9e-09 35.4 0.1 2e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EGO58525.1 - 1.2e-08 35.0 0.0 1.8e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO58525.1 - 2.4e-07 30.5 0.0 3.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO58525.1 - 6.7e-06 26.2 0.2 0.00013 22.0 0.1 2.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGO58525.1 - 0.018 13.7 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DFP PF04127.10 EGO58525.1 - 0.046 13.3 0.1 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Sulfate_transp PF00916.15 EGO58526.1 - 1.1e-51 175.5 2.6 1.1e-51 175.5 1.8 1.7 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGO58526.1 - 2.7e-27 94.2 4.3 8.2e-27 92.6 3.0 1.9 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGO58526.1 - 5.7e-18 64.4 0.0 1.1e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EGO58526.1 - 0.00015 21.7 0.0 0.00045 20.1 0.0 1.8 1 1 0 1 1 1 1 STAS domain EF-hand_1 PF00036.27 EGO58527.1 - 1.3e-05 24.1 0.0 0.0063 15.7 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EGO58527.1 - 0.0021 17.7 0.1 0.33 10.9 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 EGO58527.1 - 0.0062 16.6 0.1 0.012 15.7 0.0 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EGO58527.1 - 0.016 14.5 0.1 0.12 11.7 0.0 2.2 2 0 0 2 2 2 0 EF hand EF-hand_4 PF12763.2 EGO58527.1 - 0.02 14.6 0.1 0.064 13.0 0.0 1.7 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.1 EGO58527.1 - 0.026 14.1 0.1 0.68 9.5 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair CTP_transf_1 PF01148.15 EGO58528.1 - 6.4e-79 265.2 30.3 7.8e-79 264.9 21.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family UPF0233 PF06781.7 EGO58528.1 - 2.4 7.8 6.4 16 5.2 0.1 3.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0233) DUF3636 PF12331.3 EGO58529.1 - 1.5e-37 128.4 0.0 1.2e-22 80.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3636) Fib_alpha PF08702.5 EGO58529.1 - 0.048 13.7 0.3 0.1 12.7 0.2 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.1 EGO58529.1 - 0.25 10.2 6.4 0.67 8.8 4.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.4 EGO58529.1 - 0.87 7.7 6.7 1.4 7.0 4.7 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF342 PF03961.8 EGO58529.1 - 1.4 7.2 7.0 2.2 6.6 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Thiolase_N PF00108.18 EGO58531.1 - 1e-72 244.2 0.3 1.5e-72 243.7 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGO58531.1 - 1.5e-41 140.6 0.2 3.9e-41 139.3 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 EGO58531.1 - 0.067 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Glyco_hydro_cc PF11790.3 EGO58532.1 - 1.3e-68 230.9 0.3 1.5e-68 230.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Aldedh PF00171.17 EGO58533.1 - 8.3e-144 479.3 0.0 1e-143 479.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Metallophos_C PF14008.1 EGO58534.1 - 1.1e-20 73.4 0.3 3.4e-20 71.8 0.2 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 EGO58534.1 - 1.1e-19 70.5 0.6 4.5e-19 68.6 0.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.5 EGO58534.1 - 1.3e-08 33.8 0.0 4.5e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EGO58534.1 - 0.00065 19.5 1.0 0.0018 18.1 0.7 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SMP PF04927.7 EGO58535.1 - 0.012 15.5 0.5 0.017 15.0 0.3 1.2 1 0 0 1 1 1 0 Seed maturation protein Kelch_5 PF13854.1 EGO58536.1 - 1.2e-13 50.6 5.9 1.8e-11 43.7 0.1 4.6 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 EGO58536.1 - 0.00024 21.1 14.2 0.059 13.5 0.2 6.4 7 1 0 7 7 7 2 Galactose oxidase, central domain SKG6 PF08693.5 EGO58536.1 - 0.012 14.8 0.3 0.026 13.8 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_6 PF13964.1 EGO58536.1 - 0.02 15.0 12.4 3.7 7.8 0.1 6.2 5 2 1 6 6 6 0 Kelch motif Kelch_2 PF07646.10 EGO58536.1 - 0.05 13.4 9.0 3.8 7.4 0.0 6.0 6 0 0 6 6 6 0 Kelch motif Glyco_hydro_43 PF04616.9 EGO58537.1 - 2.3e-104 348.4 2.2 2.3e-104 348.4 1.5 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 YhhN PF07947.9 EGO58538.1 - 3.1e-36 124.4 14.7 4.5e-36 123.9 10.2 1.2 1 0 0 1 1 1 1 YhhN-like protein MFS_1 PF07690.11 EGO58538.1 - 0.012 14.3 12.7 0.016 13.9 8.8 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF3884 PF13024.1 EGO58539.1 - 0.13 11.6 0.1 0.13 11.6 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3884) MFS_1 PF07690.11 EGO58540.1 - 3.1e-32 111.6 28.1 4.1e-32 111.2 19.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily EXS PF03124.9 EGO58540.1 - 0.49 9.3 6.1 0.075 12.0 0.7 2.1 2 1 0 2 2 2 0 EXS family PI-PLC-X PF00388.14 EGO58541.1 - 8.4e-50 167.9 0.0 1.4e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EGO58541.1 - 2e-31 108.4 0.0 4.2e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EGO58541.1 - 0.021 14.6 1.9 0.14 11.9 0.7 2.7 2 1 0 2 2 2 0 C2 domain Zip PF02535.17 EGO58542.1 - 7.3e-43 146.7 1.1 1.3e-42 145.9 0.7 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter 5_nucleotid_C PF02872.13 EGO58543.1 - 2.9e-34 118.3 0.1 5.8e-34 117.3 0.1 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EGO58543.1 - 4.9e-12 45.6 0.2 9.7e-11 41.4 0.1 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.1 EGO58543.1 - 0.00059 18.9 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 YmdB-like protein Hce2 PF14856.1 EGO58544.1 - 5.1e-21 74.3 1.0 7.2e-20 70.7 0.7 2.0 1 1 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor TPR_11 PF13414.1 EGO58545.1 - 1.6e-11 43.7 1.2 1.3e-06 27.9 0.1 5.3 4 1 1 5 5 5 2 TPR repeat TPR_2 PF07719.12 EGO58545.1 - 2.9e-10 39.2 9.4 0.00046 19.8 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGO58545.1 - 1.3e-07 30.8 4.0 0.0082 15.7 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGO58545.1 - 0.00018 21.0 3.0 0.1 12.4 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGO58545.1 - 0.00025 20.9 7.5 0.012 15.4 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO58545.1 - 0.00058 20.4 8.2 0.001 19.6 0.1 4.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGO58545.1 - 0.0049 17.3 8.7 0.066 13.8 0.1 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO58545.1 - 0.04 13.7 0.4 0.57 10.1 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EGO58545.1 - 0.09 13.0 0.2 2.3 8.6 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat GYF PF02213.11 EGO58546.1 - 3.5e-20 71.3 0.1 7.3e-20 70.3 0.1 1.6 1 0 0 1 1 1 1 GYF domain SnoaL_2 PF12680.2 EGO58547.1 - 0.00031 21.0 0.1 0.00071 19.9 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EGO58547.1 - 0.00033 20.2 0.0 0.00073 19.1 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase Abhydrolase_6 PF12697.2 EGO58547.1 - 0.00062 19.7 0.0 0.00082 19.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EGO58549.1 - 7.2e-48 162.6 0.1 1.1e-47 162.1 0.1 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EGO58549.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.6 EGO58549.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Cutinase PF01083.17 EGO58550.1 - 3e-54 183.4 8.9 3.4e-54 183.2 6.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EGO58550.1 - 3.7e-06 26.5 0.0 5.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 EGO58550.1 - 0.00017 21.2 0.2 0.001 18.6 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGO58550.1 - 0.014 15.2 0.2 0.027 14.3 0.1 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO58550.1 - 0.034 13.9 0.6 0.069 12.9 0.4 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family LIP PF03583.9 EGO58550.1 - 0.12 11.5 0.2 0.19 10.8 0.2 1.3 1 0 0 1 1 1 0 Secretory lipase TRAP_alpha PF03896.11 EGO58553.1 - 0.0062 15.5 0.2 0.0089 15.0 0.1 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit SKG6 PF08693.5 EGO58554.1 - 0.025 13.8 0.5 0.075 12.3 0.4 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PepSY_TM_3 PF13706.1 EGO58554.1 - 0.13 11.7 1.6 0.25 10.7 1.1 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix Adeno_E3_CR2 PF02439.10 EGO58554.1 - 0.36 10.4 0.0 0.61 9.6 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Nop14 PF04147.7 EGO58555.1 - 0.15 9.9 8.4 0.18 9.6 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 EGO58555.1 - 9.5 5.8 11.0 18 4.9 7.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FYVE PF01363.16 EGO58556.1 - 2.1e-21 75.5 21.9 2.7e-16 59.2 3.1 3.1 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.3 EGO58556.1 - 0.00036 20.0 1.8 0.00036 20.0 1.3 2.5 3 0 0 3 3 3 1 Rabenosyn Rab binding domain zf-AN1 PF01428.11 EGO58556.1 - 0.0028 17.4 4.0 0.0028 17.4 2.8 3.6 5 0 0 5 5 5 2 AN1-like Zinc finger zf-Di19 PF05605.7 EGO58556.1 - 0.0033 17.5 7.8 0.065 13.3 0.1 2.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.7 EGO58556.1 - 0.042 12.3 3.8 1.6 7.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Cob_adeno_trans PF01923.13 EGO58556.1 - 0.13 12.0 5.4 0.13 11.9 0.9 2.7 3 0 0 3 3 3 0 Cobalamin adenosyltransferase zf-C2H2_2 PF12756.2 EGO58556.1 - 0.35 11.0 9.7 1.1 9.3 0.0 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EGO58556.1 - 1.2 9.4 11.0 0.4 10.9 0.2 3.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2HC5 PF06221.8 EGO58556.1 - 3 7.6 19.4 0.51 10.1 0.4 4.2 4 1 1 5 5 5 0 Putative zinc finger motif, C2HC5-type zf-DHHC PF01529.15 EGO58556.1 - 4.4 6.6 7.9 1.5 8.1 0.9 2.4 2 0 0 2 2 2 0 DHHC palmitoyltransferase NAD_binding_7 PF13241.1 EGO58557.1 - 3.1e-28 98.0 0.0 5.2e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EGO58557.1 - 1.2e-23 82.1 0.4 2.5e-23 81.1 0.2 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EGO58557.1 - 6.8e-15 53.7 0.2 1.2e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.1 EGO58557.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EGO58557.1 - 0.11 12.5 0.2 0.28 11.2 0.2 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase zf-H2C2_5 PF13909.1 EGO58558.1 - 2e-09 37.1 22.0 0.065 13.4 0.2 6.2 6 0 0 6 6 6 5 C2H2-type zinc-finger domain DUF1644 PF07800.7 EGO58558.1 - 2.8e-05 24.0 22.1 0.036 13.9 0.5 5.5 1 1 5 6 6 6 4 Protein of unknown function (DUF1644) Sina PF03145.11 EGO58558.1 - 8.9e-05 22.2 25.9 0.36 10.4 0.8 4.5 1 1 3 4 4 4 4 Seven in absentia protein family zf-C2H2_4 PF13894.1 EGO58558.1 - 0.0069 16.6 29.4 0.39 11.1 0.6 6.6 7 0 0 7 7 7 3 C2H2-type zinc finger Trefoil PF00088.13 EGO58558.1 - 0.12 12.0 4.1 2.3 7.9 0.0 4.0 5 0 0 5 5 5 0 Trefoil (P-type) domain zf-C2H2 PF00096.21 EGO58558.1 - 0.4 11.1 0.2 0.4 11.1 0.1 6.5 7 2 0 7 7 7 0 Zinc finger, C2H2 type DUF3505 PF12013.3 EGO58558.1 - 1.9 8.7 20.2 1.5 9.0 0.4 4.7 3 2 2 5 5 5 0 Protein of unknown function (DUF3505) Ank_2 PF12796.2 EGO58559.1 - 9.7e-16 57.8 0.4 3.6e-06 27.2 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO58559.1 - 1e-14 54.5 2.7 1.1e-08 35.3 0.3 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EGO58559.1 - 2.8e-12 45.8 2.3 0.00012 21.6 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EGO58559.1 - 1e-10 41.4 3.7 0.00058 20.0 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO58559.1 - 2e-10 39.8 0.8 0.0028 17.7 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EGO58559.1 - 5.7e-06 25.9 0.2 2.9e-05 23.6 0.2 2.1 1 1 0 1 1 1 1 KilA-N domain TMF_DNA_bd PF12329.3 EGO58559.1 - 0.064 13.0 14.1 0.62 9.9 5.6 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding COG2 PF06148.6 EGO58559.1 - 1.7 8.5 6.3 0.58 10.0 1.5 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TBPIP PF07106.8 EGO58559.1 - 2.6 7.5 8.4 1.1 8.7 3.7 1.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Complex1_LYR PF05347.10 EGO58560.1 - 9.3e-08 31.7 1.1 2.5e-07 30.3 0.8 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGO58560.1 - 3.8e-07 30.2 1.6 1e-06 28.8 1.1 1.8 1 0 0 1 1 1 1 Complex1_LYR-like Trans_reg_C PF00486.23 EGO58560.1 - 0.036 13.9 0.3 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Acetyltransf_1 PF00583.19 EGO58561.1 - 3.6e-13 49.3 0.0 6.5e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGO58561.1 - 1.2e-05 24.9 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EGO58561.1 - 3.2e-05 24.0 0.0 5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGO58561.1 - 0.0018 18.4 0.0 0.003 17.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGO58561.1 - 0.0043 17.1 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGO58561.1 - 0.041 13.8 0.0 0.38 10.6 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain 5_nucleotid_C PF02872.13 EGO58562.1 - 1.1e-38 132.6 0.0 1.9e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EGO58562.1 - 1.6e-06 27.6 0.1 2.3e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGO58562.1 - 0.019 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain CENP-L PF13092.1 EGO58563.1 - 8.6e-51 171.9 0.0 2.3e-50 170.5 0.0 1.8 1 1 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 VIT1 PF01988.14 EGO58563.1 - 2 7.8 7.4 0.29 10.5 1.9 1.8 1 1 1 2 2 2 0 VIT family zf-C2H2_4 PF13894.1 EGO58565.1 - 0.015 15.6 14.9 0.42 11.0 0.3 4.6 3 2 1 4 4 4 0 C2H2-type zinc finger DUF3740 PF12548.3 EGO58565.1 - 0.065 13.5 2.0 0.15 12.3 0.1 2.3 2 0 0 2 2 2 0 Sulfatase protein HET PF06985.6 EGO58568.1 - 4e-21 75.6 8.1 9e-20 71.2 0.1 3.0 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Beta_elim_lyase PF01212.16 EGO58568.1 - 0.053 12.6 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Abhydrolase_3 PF07859.8 EGO58569.1 - 5.9e-25 88.0 0.0 1.1e-24 87.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGO58569.1 - 8.7e-15 54.2 0.0 1.4e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGO58569.1 - 0.00021 21.0 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO58569.1 - 0.011 14.9 0.0 0.023 13.9 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Aminotran_5 PF00266.14 EGO58570.1 - 4.2e-23 81.6 0.0 9.6e-23 80.5 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGO58570.1 - 0.00061 18.8 0.0 0.0025 16.8 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II SLA_LP_auto_ag PF05889.8 EGO58570.1 - 0.094 11.1 0.1 0.17 10.3 0.1 1.4 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Epimerase PF01370.16 EGO58571.1 - 3.6e-11 42.9 0.0 4.7e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGO58571.1 - 1.5e-08 33.8 0.0 2.9e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EGO58571.1 - 3.7e-07 30.2 0.1 8.6e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGO58571.1 - 3.9e-07 29.9 0.0 6.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EGO58571.1 - 0.00059 18.6 0.0 0.0012 17.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGO58571.1 - 0.0011 19.0 0.1 0.002 18.1 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGO58571.1 - 0.023 13.9 0.1 0.031 13.5 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 EGO58571.1 - 0.076 11.9 0.0 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF867 PF05908.6 EGO58571.1 - 0.17 10.9 0.0 0.33 10.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF867) FAD_binding_3 PF01494.14 EGO58572.1 - 5.8e-16 58.5 0.0 2.5e-07 30.1 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 EGO58572.1 - 0.00021 20.3 1.8 0.0004 19.4 0.8 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGO58572.1 - 0.00091 19.5 2.4 0.0056 17.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO58572.1 - 0.0024 17.8 0.1 0.0067 16.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EGO58572.1 - 0.022 13.5 0.0 3.9 6.2 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.9 EGO58572.1 - 0.048 12.2 0.1 1.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EGO58572.1 - 0.098 12.5 1.0 0.19 11.5 0.7 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IncA PF04156.9 EGO58573.1 - 0.019 14.5 0.1 0.028 14.0 0.1 1.2 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 EGO58574.1 - 0.15 12.4 1.2 0.25 11.7 0.8 1.4 1 0 0 1 1 1 0 SlyX XAP5 PF04921.9 EGO58578.1 - 3.5e-85 285.3 0.2 3.5e-85 285.3 0.1 1.6 2 0 0 2 2 2 1 XAP5, circadian clock regulator Methyltransf_10 PF05971.7 EGO58579.1 - 1.5e-61 208.1 0.0 2.4e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_18 PF12847.2 EGO58579.1 - 4e-05 24.1 0.0 7.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO58579.1 - 0.0019 18.1 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO58579.1 - 0.002 17.3 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGO58579.1 - 0.0066 15.8 0.0 0.026 13.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 EGO58579.1 - 0.028 14.0 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein MAGE_N PF12440.3 EGO58579.1 - 9.9 6.5 9.5 0.16 12.2 1.3 1.9 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal DUF4414 PF14377.1 EGO58580.1 - 1.4e-12 47.4 0.4 1.4e-12 47.4 0.3 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4414) PKD_channel PF08016.7 EGO58581.1 - 2.7e-06 26.0 17.4 5.1e-05 21.8 12.1 2.1 1 1 0 1 1 1 1 Polycystin cation channel Med9 PF07544.8 EGO58581.1 - 2 8.2 4.7 3.8 7.3 1.5 2.3 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Sugar_tr PF00083.19 EGO58582.1 - 3.3e-32 111.6 12.9 4e-32 111.3 8.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO58582.1 - 4e-07 29.0 16.8 1.8e-05 23.6 12.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Gate PF07670.9 EGO58582.1 - 0.00015 21.6 4.0 0.00029 20.6 2.8 1.5 1 0 0 1 1 1 1 Nucleoside recognition Fungal_trans PF04082.13 EGO58583.1 - 2.1e-09 36.6 0.0 3.3e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO58583.1 - 6.6e-06 25.9 7.2 1.4e-05 24.9 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EGO58584.1 - 2.1e-37 128.7 23.9 4.3e-37 127.7 16.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO58584.1 - 5.2e-30 104.3 51.9 5.5e-29 100.9 21.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EGO58584.1 - 0.00043 18.9 17.5 0.0072 14.8 3.0 2.3 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like Rib_5-P_isom_A PF06026.9 EGO58585.1 - 7.3e-40 136.1 0.0 7.8e-39 132.7 0.0 2.0 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) MFS_1 PF07690.11 EGO58586.1 - 2.9e-19 68.9 15.8 4.2e-19 68.4 10.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4500 PF14937.1 EGO58586.1 - 0.08 12.7 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) DUF308 PF03729.8 EGO58586.1 - 0.2 11.6 7.4 0.8 9.7 5.1 2.1 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) TauD PF02668.11 EGO58587.1 - 2.2e-41 142.2 0.1 2.8e-41 141.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Plasmod_MYXSPDY PF07981.6 EGO58587.1 - 0.088 12.5 0.3 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY Porphobil_deamC PF03900.10 EGO58592.1 - 0.016 15.2 0.2 0.028 14.5 0.1 1.3 1 0 0 1 1 1 0 Porphobilinogen deaminase, C-terminal domain PNRC PF15365.1 EGO58593.1 - 0.014 15.3 2.2 0.044 13.8 1.5 1.8 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator FAD_binding_4 PF01565.18 EGO58597.1 - 5e-19 68.1 1.0 2.2e-18 66.0 0.2 2.5 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.7 EGO58597.1 - 3.9e-14 52.2 0.0 1.2e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like MFS_1 PF07690.11 EGO58598.1 - 1.5e-23 83.1 30.1 4.1e-23 81.6 20.8 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Zip PF02535.17 EGO58599.1 - 5.1e-53 180.1 0.5 1e-52 179.1 0.4 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter WBS28 PF15164.1 EGO58599.1 - 0.053 12.6 0.2 0.093 11.8 0.1 1.3 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue RhoGAP PF00620.22 EGO58600.1 - 2.8e-11 43.2 0.0 4.2e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Aminotran_3 PF00202.16 EGO58602.1 - 2.8e-87 292.7 0.0 4.6e-87 292.0 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-III SIR2 PF02146.12 EGO58603.1 - 1.6e-28 99.6 0.1 1.1e-25 90.4 0.1 2.2 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EGO58603.1 - 0.0058 16.3 0.0 3 7.5 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF2347 PF09804.4 EGO58604.1 - 4.6 6.4 12.7 6.5 5.9 8.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) AAA_17 PF13207.1 EGO58605.1 - 3.7e-09 37.4 0.0 7e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO58605.1 - 2.7e-08 34.1 0.1 1.2e-07 32.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO58605.1 - 7.7e-08 32.3 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EGO58605.1 - 2e-07 30.9 0.0 0.0021 17.9 0.0 2.2 2 0 0 2 2 2 2 Shikimate kinase AAA PF00004.24 EGO58605.1 - 0.00035 20.7 0.0 0.001 19.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGO58605.1 - 0.00054 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EGO58605.1 - 0.00055 18.7 0.0 0.0008 18.2 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 EGO58605.1 - 0.0035 16.4 0.0 0.0078 15.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Cytidylate_kin2 PF13189.1 EGO58605.1 - 0.0063 16.4 0.0 0.057 13.3 0.0 2.0 2 0 0 2 2 2 1 Cytidylate kinase-like family Arch_ATPase PF01637.13 EGO58605.1 - 0.0086 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_28 PF13521.1 EGO58605.1 - 0.0092 15.9 0.0 0.034 14.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGO58605.1 - 0.013 15.5 0.0 0.045 13.8 0.0 1.8 2 1 1 3 3 3 0 AAA domain APS_kinase PF01583.15 EGO58605.1 - 0.016 14.8 0.0 0.077 12.6 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase T2SE PF00437.15 EGO58605.1 - 0.021 13.7 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Parvo_NS1 PF01057.12 EGO58605.1 - 0.045 12.6 0.1 0.061 12.1 0.1 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 EGO58605.1 - 0.047 13.8 0.0 0.086 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase CoaE PF01121.15 EGO58605.1 - 0.051 12.9 0.0 0.53 9.6 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase NTPase_1 PF03266.10 EGO58605.1 - 0.06 13.0 0.1 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.1 EGO58605.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EGO58605.1 - 0.097 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter UPF0079 PF02367.12 EGO58605.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EGO58605.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Glycophorin_A PF01102.13 EGO58606.1 - 0.007 16.1 0.1 0.019 14.7 0.1 1.7 1 0 0 1 1 1 1 Glycophorin A Condensin2nSMC PF12422.3 EGO58606.1 - 0.0085 15.8 0.0 0.017 14.9 0.0 1.4 1 1 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit Plasmodium_Vir PF05795.6 EGO58606.1 - 0.01 15.0 0.1 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MAS20 PF02064.10 EGO58606.1 - 0.017 15.0 1.1 0.033 14.0 0.8 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor DUF106 PF01956.11 EGO58606.1 - 0.019 14.4 7.2 0.04 13.4 5.0 1.8 1 1 0 1 1 1 0 Integral membrane protein DUF106 Nucleoside_tran PF01733.13 EGO58606.1 - 0.043 12.9 0.5 0.064 12.4 0.3 1.2 1 0 0 1 1 1 0 Nucleoside transporter 7tm_1 PF00001.16 EGO58606.1 - 0.044 12.9 0.2 0.066 12.3 0.1 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Fe_bilin_red PF05996.7 EGO58606.1 - 0.057 12.8 1.5 0.087 12.2 1.0 1.2 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase YMF19 PF02326.10 EGO58606.1 - 0.066 13.7 0.5 0.13 12.8 0.3 1.6 1 0 0 1 1 1 0 Plant ATP synthase F0 ACR_tran PF00873.14 EGO58606.1 - 0.068 10.5 3.0 0.091 10.1 2.1 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DDHD PF02862.12 EGO58606.1 - 0.075 12.8 1.8 5.9 6.6 0.0 2.1 1 1 1 2 2 2 0 DDHD domain Sre PF03125.13 EGO58606.1 - 0.089 11.7 0.7 0.13 11.1 0.5 1.2 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor DUF2215 PF10225.4 EGO58606.1 - 0.13 11.6 0.8 0.25 10.7 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) K_trans PF02705.11 EGO58606.1 - 0.14 10.4 0.7 0.2 9.9 0.5 1.2 1 0 0 1 1 1 0 K+ potassium transporter Peroxin-13_N PF04088.8 EGO58606.1 - 0.28 11.1 4.0 6.3 6.7 0.4 2.5 2 1 0 2 2 2 0 Peroxin 13, N-terminal region Perilipin PF03036.11 EGO58606.1 - 0.33 9.7 14.1 0.031 13.1 2.9 2.2 1 1 2 3 3 3 0 Perilipin family OAD_gamma PF04277.8 EGO58606.1 - 0.36 11.2 7.4 23 5.4 5.1 3.0 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Helitron_like_N PF14214.1 EGO58606.1 - 2.5 7.7 6.0 15 5.2 2.2 2.3 1 1 1 2 2 2 0 Helitron helicase-like domain at N-terminus Prominin PF05478.6 EGO58606.1 - 4.5 4.6 5.7 2.6 5.4 1.4 1.9 1 1 0 2 2 2 0 Prominin Activator-TraM PF11657.3 EGO58608.1 - 0.056 12.9 0.5 0.094 12.2 0.3 1.4 1 0 0 1 1 1 0 Transcriptional activator TraM HlyD PF00529.15 EGO58608.1 - 0.14 11.4 2.4 0.17 11.1 1.7 1.2 1 0 0 1 1 1 0 HlyD family secretion protein PP2C_C PF07830.8 EGO58608.1 - 0.71 10.0 2.6 0.72 10.0 0.1 2.2 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain Nop14 PF04147.7 EGO58610.1 - 0.76 7.6 20.8 1.2 7.0 14.4 1.2 1 0 0 1 1 1 0 Nop14-like family TroA PF01297.12 EGO58611.1 - 0.072 12.3 0.0 1.1 8.4 0.0 2.3 2 1 0 2 2 2 0 Periplasmic solute binding protein family DUF4551 PF15087.1 EGO58612.1 - 2.3 6.4 3.9 3.7 5.7 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Phi_1 PF04674.7 EGO58613.1 - 0.053 12.6 0.0 2.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Phosphate-induced protein 1 conserved region Pentapeptide PF00805.17 EGO58621.1 - 9.2e-05 21.5 2.8 9.2e-05 21.5 1.9 2.2 2 1 0 2 2 2 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 EGO58621.1 - 0.037 13.8 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) DUF2604 PF10790.4 EGO58622.1 - 0.11 12.6 1.2 11 6.2 0.0 3.1 3 0 0 3 3 3 0 Protein of Unknown function (DUF2604) GRP PF07172.6 EGO58624.1 - 0.00012 22.5 14.7 0.00014 22.2 10.2 1.3 1 0 0 1 1 1 1 Glycine rich protein family Fip1 PF05182.8 EGO58629.1 - 5.9e-21 73.4 1.0 9.4e-21 72.8 0.7 1.3 1 0 0 1 1 1 1 Fip1 motif Sigma70_ner PF04546.8 EGO58629.1 - 0.78 9.3 3.1 1.3 8.5 2.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region ORC6 PF05460.8 EGO58629.1 - 1.2 8.2 8.3 1.7 7.6 5.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ebola_NP PF05505.7 EGO58629.1 - 2 6.3 7.1 2.7 5.9 5.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Dicty_REP PF05086.7 EGO58629.1 - 6.3 4.4 7.1 8.2 4.0 4.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nucleoporin_FG PF13634.1 EGO58630.1 - 3.7e-23 81.9 145.2 1.7e-13 50.8 31.9 5.6 2 1 3 5 5 5 4 Nucleoporin FG repeat region ScpA_ScpB PF02616.9 EGO58630.1 - 0.2 11.2 0.7 0.48 9.9 0.4 1.6 2 0 0 2 2 2 0 ScpA/B protein RNA_pol_3_Rpc31 PF11705.3 EGO58631.1 - 1.4e-38 133.1 14.7 2.4e-38 132.3 10.2 1.4 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Na_trans_assoc PF06512.8 EGO58631.1 - 0.023 14.6 1.1 0.041 13.8 0.7 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Sec7 PF01369.15 EGO58633.1 - 4.6e-65 218.8 0.5 4.6e-65 218.8 0.3 3.0 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.2 EGO58633.1 - 2.4e-52 176.7 2.3 2.4e-52 176.7 1.6 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EGO58633.1 - 1.3e-31 107.9 0.2 1.3e-31 107.9 0.1 3.9 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) VBS PF08913.5 EGO58633.1 - 0.075 13.2 1.0 0.14 12.4 0.1 1.9 2 0 0 2 2 2 0 Vinculin Binding Site DUF2666 PF10869.3 EGO58633.1 - 0.097 12.6 0.0 0.81 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) Ribosomal_L31e PF01198.14 EGO58633.1 - 0.11 12.1 0.0 0.46 10.1 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L31e 2-oxoacid_dh PF00198.18 EGO58634.1 - 6.4e-75 251.3 0.1 8.2e-75 251.0 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGO58634.1 - 1.2e-18 66.5 1.2 2.7e-18 65.3 0.8 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EGO58634.1 - 2.3e-16 59.1 0.5 5.6e-16 57.8 0.3 1.7 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.3 EGO58634.1 - 0.004 17.4 0.0 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3614) Fungal_trans PF04082.13 EGO58635.1 - 1.6e-10 40.2 0.0 2.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO58635.1 - 5.9e-07 29.2 12.6 9.8e-07 28.5 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fzo_mitofusin PF04799.8 EGO58635.1 - 0.065 12.6 0.5 0.13 11.5 0.3 1.4 1 0 0 1 1 1 0 fzo-like conserved region DUF2407_C PF13373.1 EGO58635.1 - 0.21 11.5 4.5 11 5.9 0.1 3.1 3 0 0 3 3 3 0 DUF2407 C-terminal domain DUF912 PF06024.7 EGO58636.1 - 0.38 10.8 1.0 1.2e+02 2.8 0.4 4.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mucin PF01456.12 EGO58637.1 - 0.15 11.8 7.0 0.21 11.3 4.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Glyco_hydro_7 PF00840.15 EGO58640.1 - 2.8e-160 533.4 8.9 3.3e-160 533.1 6.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 zf-C2HC5 PF06221.8 EGO58641.1 - 2.9e-22 78.1 6.1 4.6e-22 77.5 4.2 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Gln-synt_C PF00120.19 EGO58642.1 - 3.3e-63 213.2 0.0 4e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EGO58642.1 - 1.1e-20 72.9 0.0 1.9e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain 2-Hacid_dh_C PF02826.14 EGO58643.1 - 1.5e-39 134.9 0.0 1.7e-24 85.9 0.0 2.9 2 1 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EGO58643.1 - 0.054 13.4 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding 3HCDH_N PF02737.13 EGO58643.1 - 0.076 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EGO58643.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent dsDNA_bind PF01984.15 EGO58644.1 - 0.014 15.3 1.6 0.018 15.0 1.1 1.1 1 0 0 1 1 1 0 Double-stranded DNA-binding domain EphA2_TM PF14575.1 EGO58644.1 - 0.097 13.0 1.3 0.13 12.6 0.9 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SIR2 PF02146.12 EGO58645.1 - 2.7e-30 105.3 0.0 3.7e-09 36.5 0.0 3.3 3 0 0 3 3 3 3 Sir2 family PGM_PMM_I PF02878.11 EGO58646.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Fungal_trans PF04082.13 EGO58647.1 - 2.4e-21 75.7 3.5 4.1e-21 75.0 2.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO58647.1 - 5.9e-09 35.6 9.2 9.9e-09 34.9 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.21 EGO58648.1 - 3.9e-70 236.2 1.4 3.8e-69 232.9 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EGO58648.1 - 7.9e-55 186.0 0.1 1.4e-54 185.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EGO58648.1 - 1.1e-53 182.7 0.1 1.8e-53 181.9 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EGO58648.1 - 1e-52 178.4 1.4 2.6e-52 177.0 0.1 2.5 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EGO58648.1 - 7.3e-43 146.3 5.3 7.6e-42 143.0 0.1 3.7 4 0 0 4 4 4 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EGO58648.1 - 1.5e-40 137.6 0.1 5.1e-40 136.0 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EGO58648.1 - 5e-24 84.3 7.3 1.6e-22 79.4 0.3 4.7 4 1 1 5 5 5 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EGO58648.1 - 2.4e-19 69.6 0.0 6.5e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EGO58648.1 - 1.3e-16 61.6 0.1 3.1e-15 57.1 0.0 3.4 4 0 0 4 4 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EGO58648.1 - 1.9e-11 43.9 0.0 3.9e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO58648.1 - 2.3e-08 34.4 0.0 2e-07 31.3 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO58648.1 - 2.1e-06 27.0 0.0 4.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 EGO58648.1 - 5.4e-06 26.5 0.0 1.5e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 EGO58648.1 - 1.2e-05 25.0 0.0 2.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO58648.1 - 1.7e-05 25.3 0.0 6.5e-05 23.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGO58648.1 - 0.0033 16.4 0.0 0.0095 14.9 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Shikimate_DH PF01488.15 EGO58648.1 - 0.0049 16.9 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NdhM PF10664.4 EGO58648.1 - 0.0082 16.0 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 Cyanobacterial and plastid NDH-1 subunit M CoA_trans PF01144.18 EGO58648.1 - 0.0094 15.1 0.0 2.1 7.4 0.0 2.5 2 0 0 2 2 2 1 Coenzyme A transferase 3Beta_HSD PF01073.14 EGO58648.1 - 0.013 14.2 0.1 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EGO58648.1 - 0.015 14.2 0.2 0.037 12.9 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Methyltransf_8 PF05148.10 EGO58648.1 - 0.029 13.9 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase TrkA_N PF02254.13 EGO58648.1 - 0.071 13.1 0.1 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain adh_short PF00106.20 EGO58650.1 - 0.00013 21.8 0.0 0.0003 20.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO58650.1 - 0.001 18.7 0.1 0.0035 17.0 0.0 1.8 2 0 0 2 2 2 1 KR domain Ank_2 PF12796.2 EGO58651.1 - 4.8e-45 151.8 2.1 4.1e-13 49.4 0.0 7.4 4 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGO58651.1 - 6.6e-30 100.1 15.2 0.0012 18.9 0.0 12.3 13 1 0 13 13 13 5 Ankyrin repeat Ank PF00023.25 EGO58651.1 - 2.5e-29 99.5 24.7 4.1e-05 23.1 0.1 11.8 12 0 0 12 12 12 5 Ankyrin repeat Ank_4 PF13637.1 EGO58651.1 - 4.7e-28 97.0 10.6 4.4e-05 23.8 0.0 9.1 6 3 3 9 9 9 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO58651.1 - 1.2e-26 92.1 14.0 0.00024 21.2 0.1 9.3 8 1 0 8 8 8 6 Ankyrin repeats (many copies) F-box-like PF12937.2 EGO58651.1 - 4.8e-05 22.9 0.1 0.00017 21.2 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO58651.1 - 0.11 12.1 0.1 0.34 10.6 0.1 1.9 1 0 0 1 1 1 0 F-box domain CDV3 PF15359.1 EGO58652.1 - 0.00043 20.3 0.6 0.00047 20.2 0.4 1.2 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 Alpha_GJ PF03229.8 EGO58652.1 - 0.25 11.6 5.4 0.42 10.9 3.7 1.4 1 1 0 1 1 1 0 Alphavirus glycoprotein J Nrf1_activ_bdg PF10492.4 EGO58652.1 - 0.67 10.4 8.3 0.35 11.3 1.7 2.1 1 1 1 2 2 2 0 Nrf1 activator activation site binding domain Mucin PF01456.12 EGO58652.1 - 2.4 7.9 7.7 2.7 7.7 5.3 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Esterase_phd PF10503.4 EGO58653.1 - 2.4e-23 82.5 1.1 3.2e-23 82.1 0.7 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EGO58653.1 - 6.1e-08 32.1 1.9 8.9e-08 31.6 1.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO58653.1 - 7e-06 25.8 0.2 8.8e-06 25.5 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO58653.1 - 3.5e-05 23.7 0.0 5.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EGO58653.1 - 0.00064 18.5 1.9 0.00092 18.0 0.2 1.9 2 0 0 2 2 2 1 Carboxylesterase family Esterase PF00756.15 EGO58653.1 - 0.0014 18.1 0.6 0.0023 17.4 0.4 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 EGO58653.1 - 0.0079 15.7 0.1 0.012 15.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold AOX PF01786.12 EGO58656.1 - 1.6e-84 282.4 0.0 2e-84 282.1 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase BTB PF00651.26 EGO58659.1 - 0.0022 17.9 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BAALC_N PF06989.7 EGO58659.1 - 0.16 12.2 1.2 0.39 11.0 0.1 2.2 2 0 0 2 2 2 0 BAALC N-terminus RRM_1 PF00076.17 EGO58660.1 - 0.0007 19.1 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO58660.1 - 0.0011 18.8 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2076 PF09849.4 EGO58662.1 - 2.4 8.1 5.1 2.5 8.0 3.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TMF_DNA_bd PF12329.3 EGO58666.1 - 0.0024 17.6 11.0 0.0024 17.6 7.6 6.7 2 1 4 7 7 7 2 TATA element modulatory factor 1 DNA binding Myosin_tail_1 PF01576.14 EGO58666.1 - 0.016 12.9 73.2 0.13 9.9 38.2 2.2 1 1 1 2 2 2 0 Myosin tail DUF904 PF06005.7 EGO58666.1 - 0.031 14.5 1.3 0.031 14.5 0.9 6.8 2 2 4 6 6 6 0 Protein of unknown function (DUF904) Reo_sigmaC PF04582.7 EGO58666.1 - 2.3 7.3 20.1 0.37 9.9 6.8 2.7 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Ank_2 PF12796.2 EGO58667.1 - 9.8e-18 64.2 0.4 9.1e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGO58667.1 - 2.8e-17 61.5 2.3 3.6e-05 23.3 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EGO58667.1 - 4.6e-17 61.6 2.0 3.3e-09 36.7 0.2 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO58667.1 - 1.3e-12 46.6 1.3 0.0012 18.8 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EGO58667.1 - 2.5e-12 46.9 1.4 8.1e-10 38.9 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Glyco_hydro_18 PF00704.23 EGO58669.1 - 1.1e-100 337.4 10.1 1.2e-100 337.2 7.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Abhydrolase_3 PF07859.8 EGO58670.1 - 9.7e-29 100.4 0.0 1.5e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGO58670.1 - 6.4e-06 26.2 0.1 9.4e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EGO58670.1 - 3.7e-05 22.3 0.0 5.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) COesterase PF00135.23 EGO58670.1 - 5.2e-05 22.1 0.0 0.008 14.9 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 EGO58670.1 - 0.0001 22.0 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO58670.1 - 0.00019 20.6 0.0 0.0004 19.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Thioesterase PF00975.15 EGO58670.1 - 0.02 15.1 0.1 0.063 13.4 0.1 1.7 1 1 0 1 1 1 0 Thioesterase domain T2SI PF02501.12 EGO58670.1 - 0.092 12.7 0.5 0.29 11.1 0.1 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein I Glyco_hydro_31 PF01055.21 EGO58671.1 - 2.1e-94 316.8 4.9 2.8e-94 316.4 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 MFS_1 PF07690.11 EGO58672.1 - 1.9e-49 168.3 23.0 1.9e-49 168.3 15.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO58672.1 - 2.9e-14 52.5 11.3 4.3e-13 48.6 2.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EGO58672.1 - 4.9e-11 41.5 2.6 7.8e-11 40.8 1.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EGO58672.1 - 0.00022 19.4 2.8 0.00045 18.4 1.9 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector OAD_gamma PF04277.8 EGO58672.1 - 0.11 12.8 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_M20 PF01546.23 EGO58673.1 - 2.5e-26 92.3 0.0 4.2e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGO58673.1 - 1.5e-12 47.2 0.0 3.3e-12 46.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EGO58673.1 - 0.0035 17.1 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 DUF755 PF05501.6 EGO58673.1 - 0.049 13.6 11.0 0.036 14.1 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SR-25 PF10500.4 EGO58673.1 - 0.67 9.3 8.9 0.083 12.3 1.7 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Mannosyl_trans3 PF11051.3 EGO58674.1 - 1e-77 261.1 0.0 3.1e-77 259.5 0.0 1.8 2 1 0 2 2 2 1 Mannosyltransferase putative DUF2284 PF10050.4 EGO58681.1 - 0.19 11.3 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) Hydrolase PF00702.21 EGO58683.1 - 2.2e-23 83.7 0.0 1.5e-22 81.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGO58683.1 - 4.7e-21 75.8 0.0 1e-20 74.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGO58683.1 - 6.3e-21 74.4 0.0 1.6e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EGO58683.1 - 7.8e-06 25.7 0.0 5e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGO58683.1 - 0.0028 17.2 0.1 0.039 13.5 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EGO58683.1 - 0.0032 16.8 0.2 1.3 8.2 0.0 3.2 3 0 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase TRAP-gamma PF07074.7 EGO58683.1 - 0.0032 17.0 4.0 0.0089 15.5 2.8 1.7 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) Ldh_1_N PF00056.18 EGO58684.1 - 1.1e-44 151.7 0.0 1.8e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EGO58684.1 - 5.7e-44 149.9 0.0 8.1e-44 149.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EGO58684.1 - 0.00011 20.9 0.0 0.00017 20.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EGO58684.1 - 0.089 13.0 0.6 0.45 10.8 0.0 2.4 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Spt20 PF12090.3 EGO58685.1 - 4.9 6.4 7.2 3.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Spt20 family DUF2457 PF10446.4 EGO58686.1 - 0.018 13.7 1.2 0.023 13.4 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Na_H_Exchanger PF00999.16 EGO58687.1 - 2.4e-39 134.9 32.5 3.1e-39 134.5 22.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pro-kuma_activ PF09286.6 EGO58688.1 - 1.4e-29 102.9 0.2 2.1e-29 102.3 0.2 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGO58688.1 - 4.7e-09 35.8 0.1 7.9e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Methyltransf_23 PF13489.1 EGO58690.1 - 4.3e-11 42.7 0.0 6.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO58690.1 - 2e-07 31.3 0.0 4.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO58690.1 - 0.0008 19.8 0.0 0.0034 17.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO58690.1 - 0.015 14.4 0.0 0.022 13.8 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EGO58690.1 - 0.052 13.1 0.0 0.15 11.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EGO58690.1 - 0.14 12.5 0.0 0.39 11.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EGO58691.1 - 1.3e-19 70.5 0.0 1.9e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO58691.1 - 5.7e-12 45.9 0.0 1.3e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO58691.1 - 1.3e-09 38.5 0.0 4.8e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO58691.1 - 9.9e-08 32.3 0.0 3.3e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO58691.1 - 2.7e-06 27.0 0.0 2.2e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO58691.1 - 4.2e-06 27.0 0.0 1.2e-05 25.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO58691.1 - 0.00038 19.6 0.0 0.0035 16.4 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EGO58691.1 - 0.00095 18.2 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EGO58691.1 - 0.0044 17.0 0.0 0.014 15.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO58691.1 - 0.0051 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EGO58691.1 - 0.0053 16.2 0.0 0.0088 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EGO58691.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.7 EGO58691.1 - 0.017 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.8 EGO58691.1 - 0.032 13.3 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 EGO58692.1 - 3e-16 59.5 0.0 4.3e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO58692.1 - 1.8e-08 34.7 0.0 3.2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO58692.1 - 9.3e-08 32.6 0.0 6.4e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO58692.1 - 4.9e-05 23.7 0.0 0.00025 21.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO58692.1 - 6.2e-05 22.6 0.0 0.00073 19.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO58692.1 - 0.0009 18.4 0.0 0.0015 17.7 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGO58692.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EGO58692.1 - 0.0032 16.5 0.0 0.0053 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EGO58692.1 - 0.0091 16.0 0.0 0.027 14.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGO58692.1 - 0.019 14.3 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.7 EGO58692.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_25 PF13649.1 EGO58692.1 - 0.027 14.8 0.0 0.067 13.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EGO58692.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CG-1 PF03859.11 EGO58693.1 - 0.063 12.8 1.1 0.07 12.6 0.8 1.1 1 0 0 1 1 1 0 CG-1 domain DUF3626 PF12294.3 EGO58693.1 - 0.083 11.9 0.1 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) Methyltransf_23 PF13489.1 EGO58694.1 - 5.2e-13 49.0 0.0 9.7e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO58694.1 - 1.3e-09 38.4 0.0 2.9e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO58694.1 - 2.1e-07 31.5 0.0 2.6e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO58694.1 - 4e-07 29.7 0.0 5.4e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO58694.1 - 0.0002 21.7 0.0 0.0012 19.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO58694.1 - 0.00027 20.1 0.0 0.0025 16.9 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGO58694.1 - 0.00031 21.0 0.0 0.00079 19.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO58694.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.7 EGO58694.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MR_MLE PF01188.16 EGO58694.1 - 0.025 15.0 0.3 0.85 10.1 0.0 2.9 3 0 0 3 3 3 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain PG_binding_1 PF01471.13 EGO58695.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Herpes_BLLF1 PF05109.8 EGO58697.1 - 1.7 6.4 36.6 2.4 5.9 25.4 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) RNA_pol_Rpo13 PF12136.3 EGO58699.1 - 0.019 14.6 0.0 0.07 12.8 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain Phage_Coat_A PF05357.8 EGO58700.1 - 0.00035 20.0 0.0 0.00061 19.3 0.0 1.4 1 0 0 1 1 1 1 Phage Coat Protein A HET PF06985.6 EGO58701.1 - 2.4e-22 79.6 10.5 1.3e-19 70.7 6.3 2.7 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Methyltransf_23 PF13489.1 EGO58703.1 - 3.2e-19 69.1 0.0 1.5e-18 67.0 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO58703.1 - 2e-11 44.2 0.0 4.8e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO58703.1 - 3.3e-10 40.5 0.0 6.1e-09 36.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO58703.1 - 4.4e-08 33.5 0.0 3.4e-07 30.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO58703.1 - 4.7e-07 29.5 0.0 8.9e-06 25.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO58703.1 - 4.9e-05 22.7 0.0 8.7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGO58703.1 - 5.1e-05 23.5 0.0 0.00016 21.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO58703.1 - 0.0002 20.5 0.0 0.0022 17.1 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EGO58703.1 - 0.0019 17.2 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.4 EGO58703.1 - 0.0029 17.0 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EGO58703.1 - 0.0082 16.1 0.0 0.043 13.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO58703.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EGO58703.1 - 0.022 14.7 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 EGO58703.1 - 0.031 13.4 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DUF938 PF06080.7 EGO58703.1 - 0.054 13.0 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_23 PF13489.1 EGO58704.1 - 9.9e-17 61.1 0.0 1.5e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO58704.1 - 1.3e-08 35.3 0.1 2e-07 31.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO58704.1 - 4.2e-08 33.5 0.0 8.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO58704.1 - 1.6e-06 27.7 0.0 2.9e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO58704.1 - 9.3e-06 26.0 0.0 4.5e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO58704.1 - 2.5e-05 24.5 0.0 7.6e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO58704.1 - 0.00021 20.7 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EGO58704.1 - 0.0024 17.0 0.1 0.036 13.1 0.0 2.3 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EGO58704.1 - 0.0078 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.7 EGO58704.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_4 PF02390.12 EGO58704.1 - 0.02 13.9 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 EGO58704.1 - 0.023 14.7 0.0 0.056 13.4 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase PrmA PF06325.8 EGO58704.1 - 0.026 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Lactamase_B_2 PF12706.2 EGO58705.1 - 1.4e-20 73.6 0.0 2.1e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGO58705.1 - 2.5e-14 53.3 0.4 7.6e-14 51.7 0.3 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGO58705.1 - 1.9e-05 24.3 4.2 0.00023 20.8 1.1 3.0 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Macoilin PF09726.4 EGO58706.1 - 8.7 4.4 7.2 9.7 4.3 5.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Nucleocapsid-N PF11030.3 EGO58708.1 - 0.12 12.2 1.3 0.13 12.0 0.9 1.2 1 0 0 1 1 1 0 Nucleocapsid protein N DUF4551 PF15087.1 EGO58708.1 - 0.16 10.3 3.3 0.18 10.1 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Tmemb_161AB PF10268.4 EGO58708.1 - 0.16 10.4 0.5 0.15 10.5 0.4 1.0 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB Methyltransf_23 PF13489.1 EGO58709.1 - 1.5e-15 57.2 0.0 4.3e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO58709.1 - 1.4e-08 35.0 0.0 2.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO58709.1 - 7.6e-07 29.6 0.0 1.5e-05 25.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO58709.1 - 1.9e-05 25.0 0.0 0.00012 22.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO58709.1 - 2.6e-05 23.8 0.0 0.00044 19.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO58709.1 - 2.7e-05 23.3 0.0 0.00048 19.3 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGO58709.1 - 0.0019 18.5 0.0 0.0049 17.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO58709.1 - 0.016 14.2 0.0 0.037 13.0 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.8 EGO58709.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGO58709.1 - 0.027 14.4 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EGO58709.1 - 0.033 13.7 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.9 EGO58709.1 - 0.041 13.2 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EGO58709.1 - 0.14 12.1 0.1 0.28 11.1 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase DUF1295 PF06966.7 EGO58713.1 - 1.1e-32 113.1 0.0 1.7e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EGO58713.1 - 3.6e-05 23.8 0.0 8.8e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 EGO58713.1 - 7.5e-05 22.5 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 EGO58713.1 - 0.0016 18.6 0.0 0.0035 17.5 0.0 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 EGO58713.1 - 0.0048 15.4 0.0 0.0074 14.8 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Dicistro_VP4 PF11492.3 EGO58715.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 Hydrolase_6 PF13344.1 EGO58716.1 - 1.1e-21 76.6 0.0 2.3e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO58716.1 - 3.7e-17 61.8 0.0 1.1e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EGO58716.1 - 9.9e-05 22.6 0.0 0.022 14.9 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO58716.1 - 0.016 15.6 0.1 0.071 13.5 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.16 EGO58717.1 - 1.2e-59 201.4 0.0 1.4e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Dispanin PF04505.7 EGO58718.1 - 9 5.9 6.2 21 4.7 4.3 1.6 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Sugarporin_N PF11471.3 EGO58720.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.4 3 1 1 4 4 4 0 Maltoporin periplasmic N-terminal extension Whi5 PF08528.6 EGO58721.1 - 2e-10 39.9 0.0 3.3e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Whi5 like DUF3328 PF11807.3 EGO58723.1 - 1.8e-44 151.9 0.8 2.4e-44 151.6 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) COesterase PF00135.23 EGO58725.1 - 8.2e-90 302.0 0.0 1.1e-89 301.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO58725.1 - 1.8e-09 37.4 0.1 6e-09 35.7 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO58725.1 - 0.043 13.5 0.0 0.086 12.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO58725.1 - 0.059 12.5 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family NAD_binding_10 PF13460.1 EGO58728.1 - 0.00014 21.9 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGO58728.1 - 0.014 14.3 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein DapB_N PF01113.15 EGO58728.1 - 0.023 14.5 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EGO58728.1 - 0.034 13.0 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGO58728.1 - 0.045 13.1 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EGO58728.1 - 0.047 12.6 0.2 0.13 11.1 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase uDENN PF03456.13 EGO58729.1 - 0.062 13.2 0.2 0.18 11.7 0.2 1.7 1 0 0 1 1 1 0 uDENN domain Dynamin_N PF00350.18 EGO58731.1 - 3.7e-36 124.4 0.1 7.3e-36 123.5 0.1 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGO58731.1 - 1e-17 63.8 0.4 2e-16 59.6 0.4 2.3 1 1 1 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EGO58731.1 - 3.5e-05 23.7 0.0 0.00017 21.4 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EGO58731.1 - 0.0042 17.5 0.0 0.016 15.7 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein GED PF02212.13 EGO58731.1 - 0.0073 16.1 1.6 0.38 10.6 0.0 3.2 3 0 0 3 3 3 1 Dynamin GTPase effector domain FeoB_N PF02421.13 EGO58731.1 - 0.024 13.9 0.1 1.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.1 EGO58731.1 - 0.025 14.5 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EGO58731.1 - 0.058 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain UDPG_MGDP_dh_N PF03721.9 EGO58732.1 - 4.1e-48 163.2 0.0 4.1e-30 104.5 0.0 2.4 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EGO58732.1 - 4.9e-30 103.5 0.0 1e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EGO58732.1 - 9.9e-24 83.5 0.0 7.9e-19 67.7 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 EGO58732.1 - 0.0014 18.3 0.1 0.78 9.4 0.1 3.1 3 1 0 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EGO58732.1 - 0.0052 15.8 0.0 0.013 14.5 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase GMC_oxred_C PF05199.8 EGO58733.1 - 7.9e-33 113.7 0.0 1.3e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EGO58733.1 - 7.7e-27 94.2 0.0 2.1e-16 59.9 0.1 3.2 3 0 0 3 3 3 3 GMC oxidoreductase NAD_binding_8 PF13450.1 EGO58733.1 - 0.0022 17.9 0.2 0.0067 16.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO58733.1 - 0.0029 17.4 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGO58733.1 - 0.014 14.2 0.7 0.023 13.5 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 EGO58733.1 - 0.077 12.4 0.1 0.18 11.2 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EGO58733.1 - 0.13 10.6 0.2 0.19 10.1 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein DUF1517 PF07466.6 EGO58733.1 - 0.62 9.0 2.5 1 8.2 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF1705 PF08019.7 EGO58734.1 - 0.033 13.6 1.0 0.74 9.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) ER_lumen_recept PF00810.13 EGO58734.1 - 0.39 11.1 6.8 5.7 7.4 0.9 2.3 2 0 0 2 2 2 0 ER lumen protein retaining receptor ADH_zinc_N_2 PF13602.1 EGO58735.1 - 1.6e-19 71.0 0.0 2.6e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EGO58735.1 - 1.5e-14 53.6 0.2 3e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO58735.1 - 1.6e-06 27.8 0.4 9.2e-06 25.3 0.3 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EGO58735.1 - 0.016 14.7 0.1 0.024 14.1 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain IBR PF01485.16 EGO58736.1 - 1.4e-05 24.8 6.6 1.4e-05 24.8 4.6 2.1 2 0 0 2 2 2 1 IBR domain AA_permease_2 PF13520.1 EGO58738.1 - 2.3e-76 257.0 27.6 2.9e-76 256.7 19.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO58738.1 - 1e-12 47.1 25.2 5.7e-12 44.7 17.4 2.2 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 EGO58738.1 - 0.39 9.1 18.9 0.23 9.9 8.8 2.9 2 1 0 2 2 2 0 Transmembrane amino acid transporter protein V-SNARE_C PF12352.3 EGO58740.1 - 1.2e-13 50.8 0.8 1.2e-13 50.8 0.5 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EGO58740.1 - 3.9e-05 23.2 0.1 0.00034 20.2 0.0 2.3 2 1 1 3 3 3 1 Sec20 priB_priC PF07445.7 EGO58740.1 - 0.0027 17.1 2.2 0.081 12.3 0.6 2.1 2 0 0 2 2 2 1 Primosomal replication protein priB and priC Sigma70_r4 PF04545.11 EGO58740.1 - 0.01 15.1 0.1 0.024 13.9 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 KxDL PF10241.4 EGO58740.1 - 0.046 13.6 4.8 1.1 9.2 0.5 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF4407 PF14362.1 EGO58740.1 - 0.084 11.8 3.2 1.6 7.6 2.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.6 EGO58740.1 - 0.085 11.4 3.4 0.062 11.9 1.5 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2408 PF10303.4 EGO58740.1 - 0.35 10.9 2.5 0.49 10.5 0.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) CHCH PF06747.8 EGO58741.1 - 2.6e-07 30.3 4.6 4.1e-07 29.7 3.2 1.3 1 0 0 1 1 1 1 CHCH domain FlgN PF05130.7 EGO58741.1 - 0.84 9.8 5.2 0.87 9.8 0.9 2.1 2 0 0 2 2 2 0 FlgN protein Rotamase_2 PF13145.1 EGO58742.1 - 0.016 15.8 5.0 0.03 14.9 3.5 1.5 1 0 0 1 1 1 0 PPIC-type PPIASE domain CAF-1_p150 PF11600.3 EGO58742.1 - 0.023 14.1 10.4 0.03 13.7 7.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal YlqD PF11068.3 EGO58742.1 - 0.023 14.7 4.3 0.033 14.2 3.0 1.1 1 0 0 1 1 1 0 YlqD protein SURF2 PF05477.6 EGO58742.1 - 0.027 13.6 5.4 0.035 13.2 3.7 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) ApoO PF09769.4 EGO58742.1 - 0.033 13.9 0.1 0.043 13.5 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein O DUF2229 PF09989.4 EGO58742.1 - 0.31 10.4 1.8 0.41 10.0 1.2 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) RR_TM4-6 PF06459.7 EGO58742.1 - 0.32 10.8 7.7 0.38 10.6 5.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1682 PF07946.9 EGO58742.1 - 1.5 7.6 6.8 1.9 7.2 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) WSK PF03832.8 EGO58744.1 - 1.3 8.4 4.6 2 7.8 3.2 1.3 1 0 0 1 1 1 0 WSK motif zf-P11 PF03854.9 EGO58745.1 - 0.15 11.5 0.2 0.15 11.5 0.2 2.2 3 0 0 3 3 3 0 P-11 zinc finger tRNA-synt_1g PF09334.6 EGO58745.1 - 1.1 7.8 3.9 1.2 7.6 2.7 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) zf-NADH-PPase PF09297.6 EGO58745.1 - 2.4 7.7 9.5 5 6.7 0.1 3.2 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Rpr2 PF04032.11 EGO58745.1 - 3.5 7.5 7.0 12 5.8 4.6 1.9 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Glyco_hydro_3 PF00933.16 EGO58747.1 - 3.5e-89 298.7 0.0 5.3e-89 298.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO58747.1 - 5.8e-60 202.6 0.1 1.1e-59 201.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGO58747.1 - 9.2e-25 86.3 0.0 2e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Ser_hydrolase PF06821.8 EGO58747.1 - 0.062 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Diphtheria_C PF02763.9 EGO58747.1 - 0.074 12.4 0.2 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Diphtheria toxin, C domain Asp PF00026.18 EGO58748.1 - 3.7e-68 230.1 3.8 4.6e-68 229.8 2.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EGO58748.1 - 2.4e-06 27.9 7.6 0.00091 19.6 0.5 3.6 3 1 0 3 3 3 2 Aspartyl protease TAXi_N PF14543.1 EGO58748.1 - 4e-05 23.6 0.0 0.00056 19.9 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Myb_DNA-bind_3 PF12776.2 EGO58749.1 - 9.9e-20 70.9 0.4 2e-19 70.0 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain TALPID3 PF15324.1 EGO58749.1 - 8.5 3.5 15.7 12 3.0 10.9 1.2 1 0 0 1 1 1 0 Hedgehog signalling target Rad50_zn_hook PF04423.9 EGO58750.1 - 0.011 15.1 0.2 0.028 13.8 0.1 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif zinc-ribbons_6 PF07191.7 EGO58750.1 - 0.045 13.5 11.5 0.6 9.9 3.4 2.7 2 1 1 3 3 3 0 zinc-ribbons NinF PF05810.7 EGO58750.1 - 0.78 9.5 4.4 14 5.6 0.2 2.4 2 0 0 2 2 2 0 NinF protein zf-TFIIB PF13453.1 EGO58750.1 - 6.4 6.0 10.4 21 4.4 4.0 3.1 2 1 0 2 2 2 0 Transcription factor zinc-finger DUF3716 PF12511.3 EGO58750.1 - 7.2 6.3 11.1 3.6 7.2 5.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3716) Glyco_hydro_16 PF00722.16 EGO58752.1 - 4.7e-17 61.8 0.0 9.8e-17 60.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EGO58752.1 - 0.00045 18.5 0.8 0.33 9.0 0.4 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Zn_clus PF00172.13 EGO58753.1 - 6.8e-07 29.0 30.6 4.4e-05 23.3 6.2 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.3 EGO58753.1 - 0.012 15.3 5.6 0.025 14.3 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 EGO58753.1 - 0.12 10.3 9.9 0.2 9.5 6.8 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF2749 PF10907.3 EGO58754.1 - 0.091 12.6 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Sugar_tr PF00083.19 EGO58757.1 - 7.9e-124 413.6 24.9 9.1e-124 413.4 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO58757.1 - 5.7e-22 77.9 55.2 4e-20 71.8 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3154 PF11351.3 EGO58757.1 - 0.28 10.9 1.5 0.74 9.5 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) H_lectin PF09458.5 EGO58763.1 - 1.2 8.8 5.9 1.4 8.6 3.1 1.7 1 1 1 2 2 2 0 H-type lectin domain Pentapeptide_2 PF01469.13 EGO58766.1 - 7.9e-05 22.2 0.8 0.00039 19.9 0.5 1.9 2 0 0 2 2 2 1 Pentapeptide repeats (8 copies) PcrB PF01884.12 EGO58767.1 - 0.079 12.1 0.1 0.086 12.0 0.1 1.0 1 0 0 1 1 1 0 PcrB family FA_hydroxylase PF04116.8 EGO58770.1 - 6.4e-16 58.7 25.9 7.5e-16 58.5 15.7 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily WD40 PF00400.27 EGO58774.1 - 0.01 15.7 9.4 0.5 10.3 0.5 4.1 3 0 0 3 3 3 0 WD domain, G-beta repeat CDC45 PF02724.9 EGO58774.1 - 0.17 9.9 6.6 0.28 9.1 4.6 1.3 1 0 0 1 1 1 0 CDC45-like protein HlyIII PF03006.15 EGO58775.1 - 2.4e-63 213.5 21.0 2.8e-63 213.2 14.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related TMEM238 PF15125.1 EGO58775.1 - 0.77 9.7 9.0 0.093 12.6 1.3 2.9 3 0 0 3 3 3 0 TMEM238 protein family VIT1 PF01988.14 EGO58775.1 - 1.4 8.3 10.6 0.73 9.2 3.7 2.2 2 0 0 2 2 2 0 VIT family YfhO PF09586.5 EGO58775.1 - 6.7 4.5 10.4 0.42 8.5 0.7 2.0 1 1 1 2 2 2 0 Bacterial membrane protein YfhO Prefoldin PF02996.12 EGO58776.1 - 0.0029 17.2 0.3 0.18 11.4 0.0 2.2 1 1 1 2 2 2 1 Prefoldin subunit PSII_Pbs27 PF13326.1 EGO58776.1 - 0.011 15.7 0.3 1.1 9.2 0.0 2.2 1 1 1 2 2 2 0 Photosystem II Pbs27 DUF4472 PF14739.1 EGO58776.1 - 0.013 15.9 0.8 4.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) Fib_alpha PF08702.5 EGO58776.1 - 0.027 14.5 3.4 3 7.9 0.1 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1759 PF03564.10 EGO58776.1 - 0.17 11.7 0.6 6.8 6.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) SYCE1 PF15233.1 EGO58776.1 - 0.84 9.5 6.2 1.4 8.8 0.4 2.2 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 MscS_porin PF12795.2 EGO58776.1 - 1.4 8.1 10.5 3.2 6.9 1.0 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain IncA PF04156.9 EGO58776.1 - 2.5 7.6 5.5 8.3 5.9 0.2 2.3 2 0 0 2 2 2 0 IncA protein BLOC1_2 PF10046.4 EGO58776.1 - 2.9 8.0 8.9 8.6 6.5 0.8 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 EGO58776.1 - 8.2 6.7 9.6 11 6.3 1.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.20 EGO58778.1 - 1.1e-61 208.3 0.0 1.4e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO58778.1 - 7.8e-34 116.9 0.0 1e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO58778.1 - 3.3e-05 23.0 0.0 4.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGO58778.1 - 0.0035 16.4 0.0 0.0055 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EGO58778.1 - 0.044 12.5 0.0 0.072 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EGO58779.1 - 1.8e-54 184.5 0.0 2.8e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO58779.1 - 5.2e-24 84.7 0.0 1.5e-23 83.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO58779.1 - 0.015 14.2 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 EGO58779.1 - 0.044 12.5 0.1 0.063 12.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EGO58779.1 - 0.083 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family TMA7 PF09072.5 EGO58780.1 - 5.9e-24 84.3 20.1 6.5e-24 84.1 14.0 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DUF221 PF02714.10 EGO58781.1 - 4e-99 331.5 15.4 4e-99 331.5 10.7 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGO58781.1 - 3.6e-39 133.8 4.9 1.2e-38 132.1 3.4 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EGO58781.1 - 4.9e-15 55.8 0.7 9.4e-15 54.9 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF1192 PF06698.6 EGO58781.1 - 0.079 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) FAD_binding_4 PF01565.18 EGO58782.1 - 1.3e-30 105.6 0.7 2.1e-30 105.0 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGO58782.1 - 6.5e-15 54.7 0.4 1.7e-14 53.4 0.3 1.8 1 0 0 1 1 1 1 Berberine and berberine like Myosin_N PF02736.14 EGO58782.1 - 0.28 10.8 2.7 0.68 9.6 1.9 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain E1-E2_ATPase PF00122.15 EGO58784.1 - 5.7e-66 221.8 2.7 1e-65 221.0 1.9 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGO58784.1 - 1.5e-36 125.6 1.5 1.5e-36 125.6 1.0 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGO58784.1 - 3.9e-27 96.0 0.2 3.1e-22 80.0 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO58784.1 - 8.5e-22 76.9 0.0 2.3e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EGO58784.1 - 2.3e-15 55.7 0.7 4.4e-15 54.8 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGO58784.1 - 2.4e-10 40.9 0.0 6.6e-10 39.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGO58784.1 - 1.5e-06 27.9 0.9 1.4e-05 24.7 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3733 PF12534.3 EGO58784.1 - 0.12 11.6 0.1 0.12 11.6 0.1 2.3 3 0 0 3 3 3 0 Leucine-rich repeat containing protein 8 Glycos_transf_2 PF00535.21 EGO58785.1 - 2.4e-33 115.2 0.0 2.9e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGO58785.1 - 2e-13 50.6 0.0 4.4e-13 49.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EGO58785.1 - 3.8e-09 36.0 0.0 5.2e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGO58785.1 - 6.8e-06 25.4 0.0 9.9e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 EGO58785.1 - 0.0075 16.5 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 PCI_Csn8 PF10075.4 EGO58786.1 - 0.043 13.5 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 HTH_27 PF13463.1 EGO58786.1 - 0.15 12.4 0.6 0.34 11.2 0.1 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain CFEM PF05730.6 EGO58787.1 - 7.8e-12 44.8 9.4 7.8e-12 44.8 6.5 1.8 2 1 0 2 2 2 1 CFEM domain MFS_1 PF07690.11 EGO58788.1 - 3.5e-33 114.7 19.0 3.5e-33 114.7 13.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO58788.1 - 1.8e-12 46.5 0.0 1.8e-12 46.5 0.0 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter Gly-zipper_Omp PF13488.1 EGO58788.1 - 0.21 11.2 7.1 2.2 7.9 1.4 2.6 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.1 EGO58788.1 - 0.74 9.3 8.4 2.4 7.7 0.9 2.5 2 0 0 2 2 2 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 EGO58788.1 - 3.3 7.4 9.5 5.3 6.7 1.2 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain His_Phos_2 PF00328.17 EGO58789.1 - 2.4e-14 53.4 0.0 5.1e-13 49.0 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.20 EGO58790.1 - 1.1e-20 74.2 0.3 1.4e-20 73.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO58790.1 - 8.9e-19 68.2 0.1 1.2e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO58790.1 - 5e-08 32.8 1.1 4.9e-07 29.5 0.8 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO58790.1 - 0.0036 16.7 0.3 0.035 13.5 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO58790.1 - 0.032 14.2 1.4 1.7 8.6 0.3 2.3 2 0 0 2 2 2 0 NADH(P)-binding Rad60-SLD PF11976.3 EGO58791.1 - 8.6e-22 76.6 0.8 3.9e-19 68.1 0.8 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like KH_1 PF00013.24 EGO58792.1 - 7.2e-05 22.3 0.9 0.00019 21.0 0.6 1.7 1 0 0 1 1 1 1 KH domain MDM31_MDM32 PF08118.6 EGO58793.1 - 9.2e-188 624.7 0.0 2.3e-187 623.4 0.0 1.5 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins TraH_2 PF06871.6 EGO58793.1 - 0.0035 16.8 0.3 0.008 15.6 0.2 1.5 1 0 0 1 1 1 1 TraH_2 DUF3825 PF12873.2 EGO58793.1 - 0.17 11.0 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) eIF3_subunit PF08597.5 EGO58794.1 - 2.3e-72 243.5 22.6 2.6e-72 243.3 15.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Nop53 PF07767.6 EGO58794.1 - 0.084 11.8 28.7 0.27 10.1 0.1 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) PA26 PF04636.8 EGO58794.1 - 0.35 9.5 4.8 0.6 8.7 3.3 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Vpu PF00558.14 EGO58794.1 - 1.8 8.1 6.1 6.1 6.4 4.2 1.9 1 0 0 1 1 1 0 Vpu protein Plasmodium_Vir PF05795.6 EGO58794.1 - 3 6.9 6.5 1.3 8.1 1.2 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein AOX PF01786.12 EGO58795.1 - 2.5e-87 291.6 0.2 3.1e-87 291.3 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase zf-H2C2_2 PF13465.1 EGO58796.1 - 1.9e-13 49.9 13.7 1.5e-08 34.4 0.5 4.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EGO58796.1 - 1.6e-10 40.6 18.2 2.4e-06 27.5 1.6 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO58796.1 - 8e-09 35.2 17.8 6.8e-05 22.9 1.7 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.2 EGO58796.1 - 2e-06 27.8 2.2 0.0055 16.8 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGO58796.1 - 5.4e-05 23.2 12.9 0.025 14.7 0.2 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGO58796.1 - 0.2 11.6 10.5 1.2 9.0 0.4 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-BED PF02892.10 EGO58796.1 - 1.8 8.4 4.5 2.6 7.8 0.6 2.5 1 1 1 2 2 2 0 BED zinc finger LIM PF00412.17 EGO58796.1 - 1.9 8.6 4.8 11 6.1 0.1 2.1 1 1 1 2 2 2 0 LIM domain DUF4237 PF14021.1 EGO58798.1 - 8.4e-34 115.7 1.0 7.1e-33 112.7 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4237) GLTP PF08718.6 EGO58799.1 - 2.2e-45 154.3 0.0 3.7e-45 153.5 0.0 1.4 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) PLDc PF00614.17 EGO58800.1 - 2.1e-14 52.7 1.4 2.6e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EGO58800.1 - 5.5e-14 51.9 0.3 6.9e-06 25.8 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain Fungal_trans PF04082.13 EGO58802.1 - 6.6e-24 84.1 0.3 1.2e-23 83.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO58802.1 - 0.017 15.0 2.4 0.048 13.5 1.7 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DeoC PF01791.4 EGO58803.1 - 8.1e-44 149.6 2.0 9.5e-44 149.4 1.4 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase Glu_synthase PF01645.12 EGO58803.1 - 0.025 13.4 0.1 0.04 12.8 0.1 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase DUF1805 PF08827.6 EGO58803.1 - 0.038 13.8 0.3 5.6 6.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1805) NanE PF04131.9 EGO58803.1 - 0.051 12.5 0.1 0.099 11.6 0.1 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF218 PF02698.12 EGO58804.1 - 1.5e-11 44.0 0.0 3.6e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 DUF218 domain UPF0075 PF03702.9 EGO58804.1 - 0.1 11.4 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) Nop52 PF05997.7 EGO58805.1 - 4.6e-47 160.2 3.3 5.3e-42 143.6 1.2 2.4 1 1 1 2 2 2 2 Nucleolar protein,Nop52 Aminotran_1_2 PF00155.16 EGO58806.1 - 6.7e-82 275.3 0.0 9.6e-82 274.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EGO58806.1 - 0.033 12.7 0.0 0.046 12.2 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Syntaxin-18_N PF10496.4 EGO58808.1 - 2.5e-16 59.2 0.7 8.8e-16 57.5 0.1 2.2 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus DUF16 PF01519.11 EGO58808.1 - 0.84 9.8 4.4 3.1 8.0 1.1 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 QueC PF06508.8 EGO58808.1 - 1.8 7.7 3.9 8.1 5.6 0.1 2.4 3 0 0 3 3 3 0 Queuosine biosynthesis protein QueC DUF4407 PF14362.1 EGO58808.1 - 8.7 5.2 15.8 0.21 10.4 5.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Helicase_IV_N PF12462.3 EGO58808.1 - 9.7 5.8 9.1 0.34 10.5 0.3 2.6 3 0 0 3 3 3 0 DNA helicase IV / RNA helicase N terminal MFS_1 PF07690.11 EGO58809.1 - 1.7e-53 181.5 9.3 1.7e-53 181.5 6.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO58809.1 - 9.3e-12 44.2 9.0 9.3e-12 44.2 6.2 3.1 2 1 2 4 4 4 2 Sugar (and other) transporter DAGK_cat PF00781.19 EGO58810.1 - 2.4e-27 94.9 0.0 4.3e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NARP1 PF12569.3 EGO58811.1 - 4e-204 679.1 32.0 1.3e-202 674.2 15.2 2.4 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 EGO58811.1 - 3.2e-28 97.7 32.2 2.8e-06 27.8 4.2 8.5 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 EGO58811.1 - 8.9e-20 70.8 34.4 1.4e-07 31.7 0.1 8.3 6 3 2 8 8 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 EGO58811.1 - 3.6e-19 68.1 34.8 2.7e-06 26.9 0.1 8.3 7 2 0 8 8 7 5 TPR repeat TPR_14 PF13428.1 EGO58811.1 - 1.4e-16 59.4 36.0 0.002 18.6 0.0 12.3 8 4 5 13 13 12 4 Tetratricopeptide repeat TPR_2 PF07719.12 EGO58811.1 - 6.3e-14 50.6 45.0 0.00017 21.2 0.1 11.4 13 0 0 13 13 10 5 Tetratricopeptide repeat TPR_17 PF13431.1 EGO58811.1 - 1.1e-12 47.0 11.6 0.0004 20.3 0.0 9.3 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGO58811.1 - 1.3e-11 44.1 11.2 0.0074 16.1 0.3 6.9 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGO58811.1 - 3e-09 36.0 33.1 2.5e-05 23.6 0.2 9.9 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGO58811.1 - 1.4e-08 33.9 16.0 0.0079 15.9 0.0 9.0 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO58811.1 - 1.7e-07 31.0 26.4 0.017 15.0 0.1 8.2 6 3 3 9 9 9 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGO58811.1 - 9.1e-05 22.2 10.1 3.7 7.4 0.0 5.7 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 EGO58811.1 - 0.0026 18.0 1.7 0.0026 18.0 1.2 3.0 2 0 0 2 2 1 1 Bacterial transcriptional activator domain Mgr1 PF08602.5 EGO58811.1 - 0.0035 16.3 0.8 0.0035 16.3 0.6 2.1 2 0 0 2 2 2 1 Mgr1-like, i-AAA protease complex subunit PPTA PF01239.17 EGO58811.1 - 0.0066 15.7 1.3 0.42 10.0 0.0 3.9 4 0 0 4 4 4 1 Protein prenyltransferase alpha subunit repeat TPR_3 PF07720.7 EGO58811.1 - 0.0076 16.0 7.1 0.071 12.9 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Rapsyn_N PF10579.4 EGO58811.1 - 0.095 12.5 2.8 1.7 8.4 0.1 3.6 3 1 1 4 4 3 0 Rapsyn N-terminal myristoylation and linker region NAM-associated PF14303.1 EGO58811.1 - 0.1 12.8 13.6 1.6 9.0 0.0 3.0 3 0 0 3 3 2 0 No apical meristem-associated C-terminal domain TPR_7 PF13176.1 EGO58811.1 - 0.29 11.0 17.6 14 5.7 0.1 8.2 9 1 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGO58811.1 - 0.58 10.7 35.7 3.7 8.2 0.0 10.1 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGO58811.1 - 0.8 10.3 10.5 36 5.2 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGO58811.1 - 6.5 6.8 18.0 6 6.9 0.0 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat Cid2 PF09774.4 EGO58812.1 - 1.6e-48 164.6 0.0 1.8e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Ank_2 PF12796.2 EGO58813.1 - 6.4e-34 116.1 0.0 1.8e-11 44.2 0.1 4.5 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO58813.1 - 1.4e-28 98.7 3.4 0.00016 22.0 0.1 6.2 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 EGO58813.1 - 2.8e-23 80.4 0.0 0.00012 21.7 0.0 8.3 8 1 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 EGO58813.1 - 6.2e-20 70.7 1.6 0.0023 18.1 0.0 6.1 4 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO58813.1 - 1.9e-19 67.8 7.2 0.005 16.9 0.0 8.9 9 0 0 9 9 9 5 Ankyrin repeat Zn_clus PF00172.13 EGO58814.1 - 6.9e-08 32.2 11.0 1.4e-07 31.3 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 EGO58815.1 - 9.4e-50 168.2 0.0 1.3e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGO58815.1 - 7.4e-17 61.0 0.0 9.8e-17 60.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGO58815.1 - 8.4e-06 25.7 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 EGO58815.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase AdoHcyase PF05221.12 EGO58816.1 - 1.3e-140 466.9 0.2 1.5e-140 466.7 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EGO58816.1 - 4.6e-83 276.9 2.8 7e-83 276.3 1.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EGO58816.1 - 9.9e-06 24.8 0.1 2.5e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EGO58816.1 - 0.014 14.9 0.1 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 EGO58816.1 - 0.049 12.9 0.3 0.09 12.1 0.2 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EGO58816.1 - 0.08 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain ig PF00047.20 EGO58816.1 - 0.089 12.9 0.0 6 7.0 0.0 2.6 2 0 0 2 2 2 0 Immunoglobulin domain JAB PF01398.16 EGO58817.1 - 1.5e-08 34.4 2.1 2.1e-07 30.6 1.4 2.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GDE_N PF12439.3 EGO58817.1 - 0.12 11.5 1.0 4.8 6.3 0.2 2.2 2 0 0 2 2 2 0 Glycogen debranching enzyme N terminal Hydantoinase_B PF02538.9 EGO58818.1 - 0.13 10.5 0.1 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Mito_carr PF00153.22 EGO58819.1 - 3.4e-49 164.4 1.7 2.9e-19 68.5 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1c PF00749.16 EGO58820.1 - 2.1e-97 325.6 0.3 3.1e-97 325.0 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGO58820.1 - 6.7e-34 117.0 0.0 3.2e-33 114.8 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Macro PF01661.16 EGO58821.1 - 9.1e-41 138.4 0.4 2.1e-40 137.2 0.3 1.6 1 0 0 1 1 1 1 Macro domain Peptidase_MA_2 PF13485.1 EGO58822.1 - 0.0017 18.4 1.2 0.0041 17.1 0.1 2.2 2 0 0 2 2 2 1 Peptidase MA superfamily Peptidase_S41 PF03572.13 EGO58823.1 - 0.0019 17.6 0.0 0.0073 15.7 0.0 2.0 2 1 0 2 2 2 1 Peptidase family S41 Zeta_toxin PF06414.7 EGO58823.1 - 1.1 8.3 2.9 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.22 EGO58824.1 - 9.2e-49 165.2 0.1 1.1e-24 87.3 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGO58824.1 - 5.8e-18 65.8 0.1 0.00065 19.7 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EGO58824.1 - 3.3e-17 62.4 0.1 1.3e-05 24.5 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGO58824.1 - 5.4e-10 38.6 0.0 0.0013 18.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EGO58824.1 - 2.3e-08 34.2 0.0 0.00048 20.2 0.0 3.6 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EGO58824.1 - 2.9e-08 34.5 0.2 0.0065 17.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 EGO58824.1 - 5.7e-08 32.2 2.9 0.021 13.8 0.0 4.6 3 2 2 5 5 5 2 AAA ATPase domain DUF258 PF03193.11 EGO58824.1 - 6e-08 32.0 0.0 0.00059 19.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EGO58824.1 - 1.9e-07 31.5 8.7 0.0013 19.0 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_10 PF12846.2 EGO58824.1 - 2.8e-07 30.2 0.1 0.25 10.7 0.0 4.3 4 1 0 4 4 4 2 AAA-like domain MMR_HSR1 PF01926.18 EGO58824.1 - 4.1e-07 29.9 0.0 0.0052 16.7 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 EGO58824.1 - 6.7e-07 29.4 0.1 0.019 14.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGO58824.1 - 2.2e-06 28.0 0.9 0.14 12.4 0.0 3.8 4 0 0 4 4 3 2 AAA domain SbcCD_C PF13558.1 EGO58824.1 - 2.4e-06 27.3 0.0 0.024 14.5 0.0 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EGO58824.1 - 2.6e-06 27.3 0.0 0.15 11.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 EGO58824.1 - 3.7e-06 26.8 0.0 0.0013 18.6 0.0 2.7 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 EGO58824.1 - 6e-06 26.7 0.0 0.033 14.6 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein ArgK PF03308.11 EGO58824.1 - 9.2e-06 24.6 0.1 0.11 11.2 0.0 2.7 2 0 0 2 2 2 2 ArgK protein MobB PF03205.9 EGO58824.1 - 2.8e-05 23.8 0.0 0.33 10.6 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B HEAT_2 PF13646.1 EGO58824.1 - 2.9e-05 24.2 8.0 0.4 10.9 3.1 4.0 1 1 3 4 4 4 3 HEAT repeats AAA PF00004.24 EGO58824.1 - 3e-05 24.2 0.0 0.56 10.4 0.0 4.1 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) ParcG PF10274.4 EGO58824.1 - 4.6e-05 23.3 1.4 0.67 9.8 0.0 3.3 1 1 2 3 3 3 1 Parkin co-regulated protein PduV-EutP PF10662.4 EGO58824.1 - 4.8e-05 22.8 0.0 0.061 12.8 0.0 2.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EGO58824.1 - 6.7e-05 23.0 0.0 0.65 10.1 0.0 2.9 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 EGO58824.1 - 0.00012 21.7 0.0 0.064 12.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 EGO58824.1 - 0.00022 20.9 0.0 0.89 9.2 0.0 3.0 2 0 0 2 2 2 2 Archaeal ATPase AAA_14 PF13173.1 EGO58824.1 - 0.00024 20.9 0.0 1.3 8.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EGO58824.1 - 0.00038 20.4 5.7 0.92 9.4 0.0 4.8 4 1 0 5 5 5 1 AAA ATPase domain DUF87 PF01935.12 EGO58824.1 - 0.0015 18.4 1.4 0.85 9.3 0.0 3.9 4 0 0 4 4 4 1 Domain of unknown function DUF87 AAA_13 PF13166.1 EGO58824.1 - 0.0019 16.7 7.1 1.3 7.3 0.0 4.4 4 1 0 4 4 4 2 AAA domain Septin PF00735.13 EGO58824.1 - 0.0022 17.0 0.7 0.76 8.7 0.0 3.1 3 0 0 3 3 3 1 Septin ATP-synt_ab PF00006.20 EGO58824.1 - 0.0022 17.5 1.1 3.6 7.0 0.0 3.4 4 0 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 EGO58824.1 - 0.0024 17.3 0.0 2.7 7.4 0.0 3.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EGO58824.1 - 0.004 16.5 0.0 5.6 6.3 0.0 3.4 4 0 0 4 4 2 0 AAA domain AAA_30 PF13604.1 EGO58824.1 - 0.0041 16.7 0.0 6.1 6.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain HEAT PF02985.17 EGO58824.1 - 0.0043 17.0 0.8 45 4.4 0.0 4.3 3 0 0 3 3 3 0 HEAT repeat MutS_V PF00488.16 EGO58824.1 - 0.0076 15.6 0.1 0.76 9.1 0.0 2.5 2 0 0 2 2 2 1 MutS domain V ATP_bind_1 PF03029.12 EGO58824.1 - 0.015 14.8 0.0 7.7 5.9 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.15 EGO58824.1 - 0.018 13.7 0.1 1.7 7.2 0.0 2.6 2 0 0 2 2 2 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.13 EGO58824.1 - 0.026 13.9 0.8 4.5 6.6 0.0 3.3 4 0 0 4 4 3 0 FtsK/SpoIIIE family T2SE PF00437.15 EGO58824.1 - 0.03 13.2 0.1 3.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein PRK PF00485.13 EGO58824.1 - 0.034 13.7 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Arm_2 PF04826.8 EGO58824.1 - 0.034 13.2 0.3 9.8 5.2 0.1 3.1 3 0 0 3 3 3 0 Armadillo-like NB-ARC PF00931.17 EGO58824.1 - 0.037 12.8 0.0 0.39 9.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.10 EGO58824.1 - 0.043 12.4 0.0 4.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Mg_chelatase PF01078.16 EGO58824.1 - 0.047 12.8 0.0 3.2 6.8 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Vitellogenin_N PF01347.17 EGO58824.1 - 0.19 9.9 2.4 0.3 9.2 1.7 1.3 1 0 0 1 1 1 0 Lipoprotein amino terminal region V-ATPase_H_C PF11698.3 EGO58824.1 - 0.32 10.9 3.9 1.2 9.1 1.4 2.4 2 0 0 2 2 2 0 V-ATPase subunit H HEAT_EZ PF13513.1 EGO58824.1 - 1.1 9.7 7.5 1e+02 3.5 0.0 5.6 6 0 0 6 6 5 0 HEAT-like repeat CsbD PF05532.7 EGO58825.1 - 3.1e-10 39.5 2.2 2.2e-05 24.0 0.1 2.1 2 0 0 2 2 2 2 CsbD-like Cu-oxidase_2 PF07731.9 EGO58826.1 - 8.4e-43 145.1 3.9 1.1e-40 138.3 0.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EGO58826.1 - 1.2e-32 112.0 0.7 8e-32 109.4 0.4 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EGO58826.1 - 4.7e-27 94.8 0.0 9.8e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Methyltransf_3 PF01596.12 EGO58827.1 - 3.3e-11 42.6 0.0 4.5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EGO58827.1 - 3.9e-09 37.2 0.0 6.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO58827.1 - 0.021 15.4 0.1 0.047 14.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain CmcI PF04989.7 EGO58827.1 - 0.021 14.1 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_26 PF13659.1 EGO58827.1 - 0.05 13.6 0.1 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EGO58827.1 - 0.066 12.7 0.1 0.098 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MFS_1 PF07690.11 EGO58828.1 - 1e-28 100.0 36.9 1e-28 100.0 25.6 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO58828.1 - 1.1e-13 50.5 9.1 1.1e-13 50.5 6.3 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EGO58828.1 - 0.00022 19.5 10.0 0.0015 16.8 6.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Methyltransf_33 PF10017.4 EGO58829.1 - 1.4e-22 79.9 0.0 2.1e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FAD_binding_3 PF01494.14 EGO58830.1 - 3.1e-71 240.3 0.0 4.3e-70 236.5 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGO58830.1 - 1.1e-39 135.7 0.0 2.3e-39 134.7 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 EGO58830.1 - 1.8e-05 23.7 0.0 0.14 10.9 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Lycopene_cycl PF05834.7 EGO58830.1 - 4.2e-05 22.6 0.1 7.8e-05 21.7 0.1 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EGO58830.1 - 0.0001 22.2 0.0 0.0003 20.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO58830.1 - 0.00031 19.7 0.0 0.015 14.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO58830.1 - 0.00058 19.9 0.1 0.0016 18.5 0.1 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO58830.1 - 0.0013 17.2 0.0 0.0021 16.5 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EGO58830.1 - 0.0033 17.8 0.0 0.15 12.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO58830.1 - 0.0048 16.8 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO58830.1 - 0.0056 15.5 0.0 0.014 14.3 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EGO58830.1 - 0.037 13.1 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 EGO58830.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mpv17_PMP22 PF04117.7 EGO58831.1 - 3.5e-22 77.8 0.2 1e-21 76.3 0.1 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.14 EGO58832.1 - 3.1e-154 513.1 0.1 3.6e-154 512.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.6 EGO58832.1 - 0.072 12.4 0.1 0.34 10.2 0.0 2.1 3 0 0 3 3 3 0 Propionate catabolism activator DSS1_SEM1 PF05160.8 EGO58833.1 - 1.9e-24 85.1 17.7 2.7e-24 84.7 12.3 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF3808 PF10300.4 EGO58834.1 - 6.1e-128 427.3 0.1 7.5e-128 427.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.1 EGO58834.1 - 0.0029 17.9 7.7 0.032 14.5 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 EGO58836.1 - 6.1e-20 72.0 0.1 8.1e-19 68.4 0.1 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO58836.1 - 2.5e-08 33.7 0.0 0.0053 16.5 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO58836.1 - 2.4e-07 30.5 0.0 5.8e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold cIII PF08134.6 EGO58837.1 - 0.14 11.7 0.6 0.36 10.4 0.4 1.7 1 0 0 1 1 1 0 cIII protein family Tetraspannin PF00335.15 EGO58837.1 - 0.44 9.7 1.8 0.51 9.5 1.2 1.2 1 0 0 1 1 1 0 Tetraspanin family Methyltransf_23 PF13489.1 EGO58839.1 - 1.3e-17 63.9 0.0 1.8e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO58839.1 - 6e-13 49.1 0.0 2.3e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO58839.1 - 2e-12 47.4 0.0 3.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO58839.1 - 2.9e-11 43.1 0.0 2.6e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EGO58839.1 - 3.5e-11 43.6 0.0 7.7e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO58839.1 - 8e-07 29.3 0.0 1.5e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EGO58839.1 - 0.0001 21.7 0.0 0.0022 17.4 0.0 2.0 2 0 0 2 2 2 1 Nodulation protein S (NodS) RrnaAD PF00398.15 EGO58839.1 - 0.00043 19.4 0.0 0.00067 18.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EGO58839.1 - 0.00075 18.9 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EGO58839.1 - 0.0031 16.9 0.0 0.0056 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase DREV PF05219.7 EGO58839.1 - 0.0075 15.1 0.0 0.068 12.0 0.0 2.0 2 0 0 2 2 2 1 DREV methyltransferase Methyltransf_26 PF13659.1 EGO58839.1 - 0.0078 16.2 0.3 0.025 14.6 0.1 1.9 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO58839.1 - 0.0086 15.2 0.0 0.11 11.6 0.0 2.4 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family TehB PF03848.9 EGO58839.1 - 0.078 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB adh_short PF00106.20 EGO58841.1 - 1.7e-26 93.1 0.7 2.4e-26 92.6 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO58841.1 - 2.1e-18 66.9 0.0 2.6e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO58841.1 - 7.2e-07 29.0 0.5 1.1e-06 28.3 0.3 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO58841.1 - 0.00017 21.6 0.0 0.00067 19.7 0.0 1.8 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGO58841.1 - 0.0006 19.3 0.3 0.0013 18.2 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EGO58841.1 - 0.0027 17.2 0.2 0.0056 16.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NmrA PF05368.8 EGO58841.1 - 0.014 14.6 0.1 0.058 12.6 0.1 1.9 1 1 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 EGO58841.1 - 0.056 12.3 0.1 0.079 11.8 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Stimulus_sens_1 PF13756.1 EGO58841.1 - 0.087 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Stimulus-sensing domain Gar1 PF04410.9 EGO58842.1 - 1.5e-38 131.7 0.2 1.5e-38 131.7 0.2 2.5 2 1 1 3 3 3 1 Gar1/Naf1 RNA binding region Internalin_N PF12354.3 EGO58842.1 - 0.21 11.2 0.7 14 5.3 0.1 2.3 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal Glyco_hydro_61 PF03443.9 EGO58845.1 - 3e-73 246.2 0.2 3.5e-73 246.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 fn3 PF00041.16 EGO58845.1 - 0.073 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain PKD PF00801.15 EGO58845.1 - 0.35 10.6 4.8 5.1 6.9 0.2 2.5 2 1 0 2 2 2 0 PKD domain HET PF06985.6 EGO58846.1 - 1.4e-31 109.4 2.0 3.3e-31 108.3 0.1 2.3 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF3306 PF11748.3 EGO58846.1 - 0.00061 20.4 5.2 0.0011 19.5 3.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3306) Trypan_PARP PF05887.6 EGO58846.1 - 0.0011 18.7 10.0 0.0022 17.7 6.9 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.7 EGO58846.1 - 0.0088 14.0 19.4 0.012 13.6 13.5 1.1 1 0 0 1 1 1 1 Nop14-like family Vfa1 PF08432.5 EGO58846.1 - 0.009 16.0 5.2 0.014 15.4 3.6 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Spore_coat_CotO PF14153.1 EGO58846.1 - 0.019 14.3 5.9 0.03 13.7 4.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO TRAP_alpha PF03896.11 EGO58846.1 - 0.03 13.3 9.4 0.047 12.6 6.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 EGO58846.1 - 0.099 12.2 19.0 0.17 11.4 13.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 EGO58846.1 - 0.14 10.8 25.7 0.21 10.2 17.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2146 PF10220.4 EGO58846.1 - 0.16 9.9 1.3 0.22 9.4 0.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) FLO_LFY PF01698.11 EGO58846.1 - 0.24 10.2 3.0 0.34 9.7 2.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DDHD PF02862.12 EGO58846.1 - 0.26 11.0 2.3 0.41 10.3 1.6 1.2 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.10 EGO58846.1 - 0.29 9.7 1.1 0.4 9.2 0.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sporozoite_P67 PF05642.6 EGO58846.1 - 0.4 8.4 4.8 0.61 7.8 3.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.7 EGO58846.1 - 0.41 9.8 17.6 0.61 9.3 12.2 1.1 1 0 0 1 1 1 0 SDA1 DUF2722 PF10846.3 EGO58846.1 - 0.6 9.0 2.5 0.87 8.5 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BUD22 PF09073.5 EGO58846.1 - 1.2 8.1 15.5 1.7 7.6 10.7 1.1 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 EGO58846.1 - 1.7 7.0 24.7 2.3 6.5 17.1 1.1 1 0 0 1 1 1 0 Daxx Family RRN3 PF05327.6 EGO58846.1 - 1.7 6.6 10.4 2.6 6.0 7.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3295 PF11702.3 EGO58846.1 - 1.8 7.4 9.4 2.6 6.9 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Ycf1 PF05758.7 EGO58846.1 - 2.8 5.5 5.8 3.8 5.1 4.0 1.1 1 0 0 1 1 1 0 Ycf1 Pox_Ag35 PF03286.9 EGO58846.1 - 3.2 7.2 11.9 5.2 6.5 8.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tim54 PF11711.3 EGO58846.1 - 4.1 5.9 7.8 6.1 5.3 5.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 YqfQ PF14181.1 EGO58846.1 - 5.3 7.0 10.1 8.8 6.3 7.0 1.2 1 0 0 1 1 1 0 YqfQ-like protein Paf1 PF03985.8 EGO58846.1 - 7 5.2 21.8 10 4.7 15.1 1.1 1 0 0 1 1 1 0 Paf1 zf-RING_2 PF13639.1 EGO58847.1 - 1.9e-05 24.3 7.8 1.9e-05 24.3 5.4 2.9 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EGO58847.1 - 0.00019 21.1 3.9 0.00019 21.1 2.7 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGO58847.1 - 0.00026 20.5 10.5 0.00082 18.9 4.7 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO58847.1 - 0.0022 17.6 2.9 0.0022 17.6 2.0 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO58847.1 - 0.0032 17.4 7.3 0.0032 17.4 5.1 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EGO58847.1 - 0.67 9.5 9.3 0.084 12.4 0.5 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 EGO58847.1 - 0.99 9.5 15.1 0.16 12.1 2.3 3.1 3 0 0 3 3 3 0 RING-H2 zinc finger Acetyltransf_7 PF13508.1 EGO58848.1 - 1.6e-09 37.7 0.0 1.6e-08 34.6 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGO58848.1 - 6.8e-06 25.9 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO58848.1 - 4.5e-05 23.4 0.0 9.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGO58848.1 - 0.0014 18.2 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EGO58848.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase OPT PF03169.10 EGO58849.1 - 3e-187 623.8 51.6 3.4e-187 623.6 35.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SNF5 PF04855.7 EGO58850.1 - 9.3e-93 310.1 0.0 1.2e-92 309.8 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EGO58850.1 - 0.001 18.3 4.0 0.0024 17.1 2.8 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF2076 PF09849.4 EGO58850.1 - 0.38 10.7 0.0 0.38 10.7 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) CENP-H PF05837.7 EGO58853.1 - 0.12 12.5 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) RNA_ligase PF09414.5 EGO58856.1 - 2.6e-15 56.7 0.0 7.4e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 RNA ligase DltD_M PF04918.7 EGO58856.1 - 0.042 14.0 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 DltD central region NAD_binding_1 PF00175.16 EGO58859.1 - 1.2e-27 96.5 0.0 1.8e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGO58859.1 - 4.1e-15 55.7 0.0 7.2e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGO58859.1 - 1.6e-08 34.6 0.0 1e-05 25.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain MFS_1 PF07690.11 EGO58860.1 - 1.2e-29 103.2 24.2 1.2e-29 103.2 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.24 EGO58861.1 - 3.8e-41 140.4 0.2 6.5e-41 139.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO58861.1 - 9.2e-16 57.4 0.0 2.1e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EGO58861.1 - 1.1e-13 50.4 0.0 2.4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EGO58861.1 - 0.0083 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Fungal_trans PF04082.13 EGO58862.1 - 0.00076 18.4 0.5 0.28 10.0 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO58862.1 - 0.0084 15.9 10.4 0.015 15.2 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.14 EGO58862.1 - 0.015 15.6 7.5 0.015 15.6 5.2 3.5 4 1 0 4 4 4 0 60s Acidic ribosomal protein PBP1_TM PF14812.1 EGO58862.1 - 0.032 14.5 0.3 0.089 13.1 0.2 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 EGO58862.1 - 0.041 13.0 0.1 0.041 13.0 0.1 2.1 3 0 0 3 3 3 0 Myc amino-terminal region Nucleoplasmin PF03066.10 EGO58862.1 - 0.081 12.4 3.8 0.2 11.1 2.6 1.6 1 0 0 1 1 1 0 Nucleoplasmin BSP_II PF05432.6 EGO58862.1 - 0.23 10.7 10.2 0.51 9.5 7.1 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Radial_spoke PF04712.7 EGO58862.1 - 0.95 8.1 5.2 1.9 7.1 3.6 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein DNA_pol_phi PF04931.8 EGO58862.1 - 9.6 3.8 4.9 14 3.3 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.5 EGO58862.1 - 9.6 6.5 8.6 9.6 6.5 4.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sugar_tr PF00083.19 EGO58863.1 - 3.7e-86 289.5 20.0 4.2e-86 289.2 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO58863.1 - 6.7e-17 61.2 28.6 1.2e-16 60.4 14.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGO58863.1 - 1e-07 30.7 18.1 0.00013 20.5 1.6 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Folate_carrier PF01770.13 EGO58863.1 - 0.00019 20.1 3.0 0.00062 18.3 2.1 1.7 1 1 0 1 1 1 1 Reduced folate carrier Alpha-amylase PF00128.19 EGO58864.1 - 7.4e-97 324.5 0.0 1e-96 324.0 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EGO58864.1 - 0.0029 16.5 0.0 0.005 15.7 0.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Cellulase PF00150.13 EGO58864.1 - 0.0034 16.6 0.2 0.0073 15.5 0.1 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PBP PF01161.15 EGO58865.1 - 1.9e-09 37.5 0.0 2.4e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein LysM PF01476.15 EGO58866.1 - 3.3e-07 30.0 0.0 1e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 LysM domain p450 PF00067.17 EGO58867.1 - 1.2e-60 205.3 0.0 1.5e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L1 PF00687.16 EGO58868.1 - 5.9e-57 192.5 1.8 5.9e-57 192.5 1.3 1.4 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Palm_thioest PF02089.10 EGO58870.1 - 4.7e-49 166.8 0.0 5.9e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PH_9 PF15410.1 EGO58870.1 - 0.025 14.7 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain DUF915 PF06028.6 EGO58870.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) CFEM PF05730.6 EGO58871.1 - 4.9e-05 23.0 5.3 9e-05 22.2 3.7 1.4 1 0 0 1 1 1 1 CFEM domain Serglycin PF04360.7 EGO58871.1 - 0.16 11.6 0.2 0.36 10.5 0.0 1.6 2 0 0 2 2 2 0 Serglycin DHO_dh PF01180.16 EGO58872.1 - 1.1e-68 231.3 0.0 2.2e-68 230.3 0.0 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 EGO58872.1 - 8.8e-06 25.1 1.1 0.069 12.3 0.0 2.3 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 EGO58872.1 - 0.087 11.6 1.8 0.19 10.5 0.6 2.0 2 1 0 2 2 2 0 FMN-dependent dehydrogenase SSP160 PF06933.6 EGO58872.1 - 0.12 10.3 9.7 0.17 9.7 6.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mpv17_PMP22 PF04117.7 EGO58873.1 - 6.2e-19 67.3 2.2 8.4e-19 66.9 0.7 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family MFS_1 PF07690.11 EGO58874.1 - 8.9e-16 57.5 29.4 1.5e-15 56.8 14.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGO58874.1 - 2.3e-07 30.4 2.3 4.8e-07 29.3 1.0 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF4131 PF13567.1 EGO58874.1 - 1.6 8.1 7.4 1.1 8.6 0.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4341 PF14241.1 EGO58874.1 - 5 6.9 10.3 0.1 12.3 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4341) zf-RING_2 PF13639.1 EGO58875.1 - 6.5e-08 32.2 7.0 1.3e-07 31.3 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EGO58875.1 - 1e-06 28.6 7.4 3.1e-06 27.0 5.1 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.2 EGO58875.1 - 4.4e-06 26.7 2.2 9.3e-06 25.6 1.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger RINGv PF12906.2 EGO58875.1 - 0.00018 21.4 6.2 0.00036 20.5 4.3 1.5 1 0 0 1 1 1 1 RING-variant domain zf-Apc11 PF12861.2 EGO58875.1 - 0.00026 20.7 2.0 0.0006 19.6 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EGO58875.1 - 0.0017 17.9 8.5 0.0035 16.9 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO58875.1 - 0.009 16.0 8.3 0.018 15.0 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGO58875.1 - 0.034 13.8 6.3 0.089 12.4 4.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EGO58875.1 - 0.13 12.2 6.8 0.22 11.5 4.7 1.4 1 0 0 1 1 1 0 RING-like domain C1_1 PF00130.17 EGO58875.1 - 0.41 10.4 4.6 0.51 10.1 2.5 1.7 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.1 EGO58875.1 - 3.8 7.3 7.9 7.1 6.4 5.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.1 EGO58875.1 - 4.5 6.9 7.4 9 5.9 5.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EGO58875.1 - 6.5 6.5 6.4 13 5.5 4.4 1.5 1 0 0 1 1 1 0 PHD-finger FAM222A PF15258.1 EGO58878.1 - 0.018 14.2 2.7 0.017 14.3 1.9 1.0 1 0 0 1 1 1 0 Protein family of FAM222A DUF4228 PF14009.1 EGO58878.1 - 0.054 13.6 1.2 0.083 13.0 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Mcm10 PF09332.6 EGO58878.1 - 0.7 9.1 5.1 0.8 8.9 3.5 1.1 1 0 0 1 1 1 0 Mcm10 replication factor Pex14_N PF04695.8 EGO58878.1 - 1.1 9.3 7.5 1.2 9.1 5.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF912 PF06024.7 EGO58879.1 - 0.0047 16.9 0.0 0.0099 15.9 0.0 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Sin_N PF04801.8 EGO58881.1 - 4.1e-06 25.9 0.0 7.3e-06 25.0 0.0 1.3 2 0 0 2 2 2 1 Sin-like protein conserved region Ribosomal_60s PF00428.14 EGO58882.1 - 0.53 10.7 10.2 0.69 10.3 7.1 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein PAT1 PF09770.4 EGO58883.1 - 7.5e-270 897.6 25.7 8.6e-270 897.4 17.8 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.11 EGO58884.1 - 2e-142 473.9 6.7 2.5e-142 473.7 4.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CDI PF02234.14 EGO58884.1 - 0.098 12.4 0.7 0.26 11.0 0.5 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Ribosom_S12_S23 PF00164.20 EGO58885.1 - 1e-39 134.7 0.9 1.2e-39 134.4 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acyl-CoA_dh_1 PF00441.19 EGO58886.1 - 4.5e-41 140.4 4.5 6.8e-41 139.8 3.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGO58886.1 - 4e-29 101.4 0.8 1.3e-28 99.8 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGO58886.1 - 2.9e-18 65.1 0.0 5.1e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGO58886.1 - 9.6e-16 58.2 1.1 9.6e-16 58.2 0.8 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EGO58886.1 - 0.012 14.9 0.3 0.061 12.7 0.2 2.1 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Pkinase PF00069.20 EGO58887.1 - 3.1e-63 213.3 0.0 6.6e-63 212.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO58887.1 - 5.8e-36 123.8 0.0 1.1e-35 122.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EGO58887.1 - 5.6e-29 99.6 18.7 5.4e-16 58.0 3.7 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EGO58887.1 - 1.4e-20 72.7 25.8 1.3e-11 44.0 7.1 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EGO58887.1 - 5.4e-14 52.4 2.2 5.4e-14 52.4 1.5 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGO58887.1 - 0.029 13.3 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like OrfB_Zn_ribbon PF07282.6 EGO58887.1 - 3.2 7.4 13.1 1.9 8.2 1.4 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain She9_MDM33 PF05546.6 EGO58888.1 - 5.8e-82 274.2 6.6 1.4e-81 273.0 4.6 1.6 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 EGO58888.1 - 0.19 11.3 0.3 0.34 10.5 0.2 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein RAP1 PF07218.6 EGO58888.1 - 0.78 7.7 6.6 1.1 7.3 4.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TMEM171 PF15471.1 EGO58888.1 - 2.4 6.8 12.5 4.3 6.0 8.7 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF1183 PF06682.7 EGO58889.1 - 0.0087 15.6 0.0 0.0087 15.6 0.0 3.5 2 1 1 4 4 4 1 Protein of unknown function (DUF1183) Rifin_STEVOR PF02009.11 EGO58889.1 - 0.012 15.2 0.1 0.022 14.4 0.1 1.4 1 0 0 1 1 1 0 Rifin/stevor family Hamartin PF04388.7 EGO58889.1 - 0.65 8.5 14.2 1 7.9 9.8 1.4 1 0 0 1 1 1 0 Hamartin protein MMR_HSR1 PF01926.18 EGO58890.1 - 1.6e-07 31.2 0.2 1.1e-06 28.5 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGO58890.1 - 6.7e-07 28.6 0.0 1.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EGO58890.1 - 0.00032 19.8 0.0 0.44 9.6 0.0 2.7 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.18 EGO58890.1 - 0.0011 18.8 0.1 0.055 13.2 0.0 2.9 3 0 0 3 3 3 1 Dynamin family AAA_29 PF13555.1 EGO58890.1 - 0.0014 18.1 0.0 0.0038 16.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.13 EGO58890.1 - 0.0055 15.7 0.1 0.029 13.4 0.1 2.2 2 1 0 2 2 2 1 Septin AAA_16 PF13191.1 EGO58890.1 - 0.025 14.5 0.0 0.076 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EGO58890.1 - 0.026 14.6 0.0 0.49 10.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.2 EGO58890.1 - 0.029 14.2 0.0 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family FtsK_SpoIIIE PF01580.13 EGO58890.1 - 0.056 12.9 0.0 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EGO58890.1 - 0.081 13.2 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 EGO58890.1 - 0.089 12.2 0.0 0.23 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain GTP_EFTU PF00009.22 EGO58890.1 - 0.096 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 EGO58890.1 - 0.12 12.6 4.5 0.27 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain LBR_tudor PF09465.5 EGO58890.1 - 0.15 11.7 1.1 17 5.1 0.2 2.7 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain SNO PF01174.14 EGO58891.1 - 3.6e-53 179.9 0.0 2.6e-52 177.2 0.0 1.9 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EGO58891.1 - 3.2e-10 39.8 0.0 3.1e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EGO58891.1 - 0.00081 18.8 0.1 0.017 14.5 0.1 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 EGO58891.1 - 0.0014 18.0 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.12 EGO58891.1 - 0.0063 16.2 0.0 0.0099 15.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 DUF4066 PF13278.1 EGO58891.1 - 0.014 14.6 0.2 0.022 14.0 0.2 1.3 1 0 0 1 1 1 0 Putative amidotransferase SOR_SNZ PF01680.12 EGO58892.1 - 2.4e-103 344.1 7.4 3.6e-103 343.6 5.1 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EGO58892.1 - 5.6e-07 28.8 9.4 0.00043 19.4 0.8 2.6 2 2 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EGO58892.1 - 3.8e-05 23.0 0.5 0.0048 16.1 0.1 2.4 2 0 0 2 2 2 2 Histidine biosynthesis protein NanE PF04131.9 EGO58892.1 - 0.00079 18.4 2.3 0.02 13.8 0.0 3.1 2 2 2 4 4 4 1 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.12 EGO58892.1 - 0.0008 18.3 0.3 0.39 9.5 0.1 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TMP-TENI PF02581.12 EGO58892.1 - 0.018 14.1 0.8 0.29 10.2 0.1 2.6 2 1 0 2 2 2 0 Thiamine monophosphate synthase/TENI DUF4398 PF14346.1 EGO58892.1 - 0.045 13.7 0.5 0.045 13.7 0.3 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) IGPS PF00218.16 EGO58892.1 - 0.052 12.6 0.0 0.43 9.5 0.0 2.3 1 1 1 2 2 2 0 Indole-3-glycerol phosphate synthase NMO PF03060.10 EGO58892.1 - 0.28 10.2 10.4 0.32 10.1 1.7 2.9 2 2 1 3 3 3 0 Nitronate monooxygenase FAR1 PF03101.10 EGO58893.1 - 5.2e-08 33.3 0.8 5.2e-08 33.3 0.6 1.9 2 0 0 2 2 2 1 FAR1 DNA-binding domain ALG3 PF05208.8 EGO58894.1 - 5.6e-160 532.5 14.1 6.4e-160 532.3 9.8 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.14 EGO58895.1 - 2.9e-19 68.2 0.1 4.1e-19 67.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 SNN_linker PF09050.5 EGO58895.1 - 0.13 11.8 6.6 0.21 11.1 0.3 2.6 2 0 0 2 2 2 0 Stannin unstructured linker HAD PF12710.2 EGO58896.1 - 1.4e-14 54.7 0.0 1.9e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EGO58896.1 - 0.00037 19.7 0.0 0.0033 16.6 0.0 2.0 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.7 EGO58896.1 - 0.0013 18.0 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 EGO58896.1 - 0.026 14.7 0.0 0.069 13.3 0.0 1.8 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Thioredoxin PF00085.15 EGO58898.1 - 3.6e-28 97.2 0.1 4.1e-28 97.1 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EGO58898.1 - 4.1e-07 30.1 0.1 4.9e-06 26.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGO58898.1 - 1.1e-06 28.5 0.0 0.00087 19.3 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 EGO58898.1 - 2.8e-05 23.7 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EGO58898.1 - 0.0021 17.5 0.2 0.081 12.4 0.1 2.0 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 EGO58898.1 - 0.025 14.6 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.16 EGO58898.1 - 0.028 14.1 0.1 0.051 13.2 0.0 1.5 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_5 PF13743.1 EGO58898.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.5 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_6 PF13848.1 EGO58898.1 - 0.096 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain DAO PF01266.19 EGO58900.1 - 2.2e-30 105.7 0.8 4.5e-30 104.7 0.5 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO58900.1 - 2e-05 23.6 0.2 3.1e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGO58900.1 - 2.5e-05 24.2 0.2 6.2e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO58900.1 - 0.00038 20.3 0.0 0.00055 19.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO58900.1 - 0.00083 18.5 2.0 0.00095 18.3 0.2 2.0 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EGO58900.1 - 0.0065 15.3 0.2 0.0095 14.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EGO58900.1 - 0.011 16.1 0.1 0.024 15.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO58900.1 - 0.022 13.2 0.7 0.031 12.7 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EGO58900.1 - 0.023 14.4 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EGO58900.1 - 0.028 14.4 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO58900.1 - 0.048 12.6 0.4 0.073 12.1 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EGO58900.1 - 0.11 11.1 0.4 0.16 10.5 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ApbA PF02558.11 EGO58900.1 - 0.14 11.6 0.7 0.26 10.7 0.5 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EGO58900.1 - 0.14 12.0 0.9 0.26 11.0 0.7 1.5 1 0 0 1 1 1 0 ThiF family FAD_oxidored PF12831.2 EGO58900.1 - 0.14 11.2 0.9 0.21 10.6 0.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGO58900.1 - 0.18 10.6 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_2 PF03446.10 EGO58901.1 - 8e-37 126.5 0.0 1.4e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EGO58901.1 - 7.9e-32 109.8 0.5 1.5e-31 108.9 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EGO58901.1 - 8.6e-08 32.5 0.1 8.4e-07 29.3 0.0 2.4 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 EGO58901.1 - 1.5e-07 30.5 0.0 2.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.17 EGO58901.1 - 2.2e-05 24.9 0.0 5.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EGO58901.1 - 0.00016 21.9 0.0 0.00036 20.8 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGO58901.1 - 0.0015 18.4 0.0 0.0044 17.0 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain 3HCDH_N PF02737.13 EGO58901.1 - 0.032 13.8 0.0 0.13 11.8 0.0 2.1 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KilA-N PF04383.8 EGO58902.1 - 0.0021 17.6 0.0 0.0073 15.9 0.0 1.9 1 1 0 1 1 1 1 KilA-N domain Rho_GDI PF02115.12 EGO58903.1 - 5.7e-56 189.1 0.0 6.8e-56 188.8 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor E1_DerP2_DerF2 PF02221.10 EGO58903.1 - 0.064 13.5 0.0 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 ML domain Metallophos PF00149.23 EGO58904.1 - 4e-42 143.8 1.0 5e-42 143.5 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-CCHC PF00098.18 EGO58906.1 - 0.00015 21.4 0.7 0.00035 20.3 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle Nuf2 PF03800.9 EGO58911.1 - 5.5e-47 159.4 0.0 5.5e-47 159.4 0.0 2.4 3 0 0 3 3 3 1 Nuf2 family Reo_sigmaC PF04582.7 EGO58911.1 - 0.67 9.0 9.8 0.26 10.4 3.5 2.4 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Thioredoxin_3 PF13192.1 EGO58911.1 - 1.4 8.8 4.3 2.4 8.0 0.3 2.8 2 0 0 2 2 2 0 Thioredoxin domain Transformer PF06495.6 EGO58911.1 - 5.4 6.8 7.9 14 5.5 5.5 1.7 1 0 0 1 1 1 0 Fruit fly transformer protein VPS11_C PF12451.3 EGO58911.1 - 6.9 6.6 6.7 2.8 7.8 0.0 3.5 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal GvpL_GvpF PF06386.6 EGO58912.1 - 0.096 12.2 0.2 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Adaptin_N PF01602.15 EGO58913.1 - 9.7e-108 360.7 0.0 1.2e-107 360.4 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EGO58913.1 - 1.6e-12 47.4 4.4 4.7e-06 26.7 0.0 5.2 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EGO58913.1 - 2.6e-08 33.2 0.4 0.036 14.1 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EGO58913.1 - 4.6e-06 26.9 6.7 0.02 15.3 0.0 5.3 5 1 1 6 6 5 2 HEAT-like repeat Cnd1 PF12717.2 EGO58913.1 - 0.0039 17.0 0.1 0.13 12.1 0.0 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EGO58913.1 - 0.0066 15.8 0.4 6.6 6.0 0.0 3.4 2 1 0 2 2 2 1 CLASP N terminal Cohesin_HEAT PF12765.2 EGO58913.1 - 0.026 14.5 0.6 0.3 11.0 0.0 2.9 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion SDA1 PF05285.7 EGO58913.1 - 0.3 10.3 24.0 0.48 9.6 16.6 1.2 1 0 0 1 1 1 0 SDA1 DDHD PF02862.12 EGO58913.1 - 1.1 8.9 6.7 2.2 8.0 4.6 1.4 1 0 0 1 1 1 0 DDHD domain PBP_sp32 PF07222.7 EGO58913.1 - 1.2 8.2 10.8 2 7.5 7.5 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 RR_TM4-6 PF06459.7 EGO58913.1 - 1.9 8.2 14.7 3.1 7.6 10.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2457 PF10446.4 EGO58913.1 - 3.6 6.2 30.9 5.9 5.4 21.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 EGO58913.1 - 9.8 3.9 31.5 16 3.2 21.8 1.2 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.8 EGO58913.1 - 9.9 6.0 16.2 16 5.3 11.2 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated DcpS_C PF11969.3 EGO58916.1 - 1.2e-15 57.7 4.9 1.8e-14 53.9 3.4 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EGO58916.1 - 7.4e-15 55.2 0.3 1.5e-14 54.2 0.2 1.5 1 0 0 1 1 1 1 HIT domain COesterase PF00135.23 EGO58917.1 - 6.2e-89 299.1 0.0 5.8e-84 282.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EGO58917.1 - 9e-06 25.4 0.1 4.6e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO58917.1 - 0.046 13.4 0.1 0.094 12.4 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family PI31_Prot_N PF11566.3 EGO58921.1 - 5.5e-37 126.7 0.0 6.6e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EGO58921.1 - 1.6e-18 67.1 21.0 1.6e-18 67.1 14.6 3.4 4 0 0 4 4 4 1 PI31 proteasome regulator T2SS-T3SS_pil_N PF13629.1 EGO58921.1 - 0.19 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Pilus formation protein N terminal region HORMA PF02301.13 EGO58922.1 - 7.3e-20 71.3 0.0 1.1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 HORMA domain IBN_N PF03810.14 EGO58923.1 - 4.3e-08 32.9 0.2 1.4e-06 28.1 0.0 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EGO58923.1 - 0.0001 22.2 0.0 0.0023 17.8 0.0 2.8 2 0 0 2 2 2 1 Exportin 1-like protein CAS_CSE1 PF03378.10 EGO58923.1 - 0.013 13.8 0.1 0.31 9.3 0.0 2.7 3 0 0 3 3 3 0 CAS/CSE protein, C-terminus RhoGEF PF00621.15 EGO58924.1 - 2.7e-23 82.7 0.6 9.4e-23 81.0 0.0 2.1 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.3 EGO58924.1 - 0.033 13.6 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) FUSC PF04632.7 EGO58924.1 - 0.095 11.1 10.2 0.2 10.0 7.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family ING PF12998.2 EGO58924.1 - 2.5 8.3 10.8 0.7 10.2 2.1 3.1 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Pentapeptide_4 PF13599.1 EGO58925.1 - 0.093 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Pkinase PF00069.20 EGO58926.1 - 7e-15 54.8 0.0 3.8e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO58926.1 - 0.0092 15.0 0.0 0.043 12.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase HET PF06985.6 EGO58928.1 - 1.2e-24 87.0 0.0 2.5e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 EGO58928.1 - 1.9e-23 82.9 0.0 3.9e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO58928.1 - 1.7e-14 53.5 0.0 2.8e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2036 PF09724.4 EGO58929.1 - 2.4e-06 26.9 0.0 2.6e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) IBR PF01485.16 EGO58930.1 - 0.0025 17.6 3.6 0.0025 17.6 2.5 2.6 2 0 0 2 2 2 1 IBR domain Rad4 PF03835.10 EGO58931.1 - 6e-34 116.5 0.2 2.8e-33 114.3 0.1 2.2 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EGO58931.1 - 7.9e-27 92.7 0.2 1.6e-26 91.8 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EGO58931.1 - 5.6e-21 73.8 0.2 1.1e-20 72.8 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EGO58931.1 - 2.4e-16 59.8 0.3 2.4e-16 59.8 0.2 3.6 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EGO58931.1 - 0.014 15.5 0.0 0.093 12.9 0.0 2.3 2 1 0 2 2 2 0 Transglutaminase-like superfamily zf-AN1 PF01428.11 EGO58932.1 - 3.4e-23 81.2 21.3 4.5e-12 45.6 2.1 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EGO58932.1 - 0.0088 16.2 11.4 0.035 14.3 1.7 2.3 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain IBR PF01485.16 EGO58932.1 - 0.021 14.6 16.6 0.038 13.8 0.9 2.5 2 0 0 2 2 2 0 IBR domain MTP18 PF10558.4 EGO58933.1 - 8.4e-70 233.4 0.0 1.1e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2611 PF11022.3 EGO58934.1 - 1.3e-22 79.6 0.1 1.9e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) DUF342 PF03961.8 EGO58937.1 - 0.12 10.7 5.0 0.13 10.6 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Elongin_A PF06881.6 EGO58937.1 - 0.16 12.3 5.2 0.3 11.4 3.6 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A ADIP PF11559.3 EGO58937.1 - 0.22 11.4 10.4 0.33 10.8 7.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding VIT1 PF01988.14 EGO58937.1 - 0.26 10.7 3.7 0.14 11.6 1.1 1.5 1 1 1 2 2 2 0 VIT family APG6 PF04111.7 EGO58937.1 - 0.41 9.6 8.5 0.56 9.1 5.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 EGO58937.1 - 0.71 10.2 10.0 7.6 6.9 5.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF883 PF05957.8 EGO58937.1 - 2.4 8.6 7.4 1.7 9.0 2.2 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) IncA PF04156.9 EGO58937.1 - 7.5 6.1 8.1 12 5.4 5.6 1.4 1 1 0 1 1 1 0 IncA protein HTH_Tnp_Tc5 PF03221.11 EGO58938.1 - 4.6e-17 61.5 3.4 2.5e-16 59.2 0.2 3.0 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain SH3_1 PF00018.23 EGO58939.1 - 3.9e-28 96.5 0.0 2.3e-13 49.3 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EGO58939.1 - 1.7e-19 69.1 0.2 4.6e-09 35.7 0.0 3.4 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 EGO58939.1 - 5.3e-14 51.9 0.0 1.2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 EGO58939.1 - 2.1e-13 49.5 0.0 3.6e-08 32.7 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain PB1 PF00564.19 EGO58939.1 - 1.1e-09 37.7 0.0 2.2e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 PB1 domain SAC3_GANP PF03399.11 EGO58940.1 - 9e-67 224.5 0.6 1.3e-66 224.0 0.4 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EGO58940.1 - 0.014 15.2 0.2 0.044 13.5 0.0 1.8 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 EAP30 PF04157.11 EGO58941.1 - 1.4e-58 197.7 0.0 1.8e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EGO58941.1 - 4.9e-27 93.5 0.0 8.2e-27 92.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.10 EGO58941.1 - 0.00011 21.6 3.9 0.0065 15.9 0.2 2.4 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger GRAM PF02893.15 EGO58941.1 - 0.00043 19.7 0.0 0.00087 18.7 0.0 1.4 1 0 0 1 1 1 1 GRAM domain zf-RanBP PF00641.13 EGO58941.1 - 0.0024 16.9 10.5 0.0086 15.1 0.4 2.6 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 EGO58941.1 - 0.34 10.7 4.1 0.23 11.3 0.3 2.2 2 0 0 2 2 2 0 Double zinc ribbon DUF3716 PF12511.3 EGO58944.1 - 8.1e-33 111.8 11.6 3.2e-16 58.6 1.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3716) Macro PF01661.16 EGO58944.1 - 0.018 14.9 0.6 0.38 10.6 0.1 2.6 2 0 0 2 2 2 0 Macro domain Lipase_GDSL_2 PF13472.1 EGO58945.1 - 1.1e-14 54.9 0.2 1.7e-14 54.3 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGO58945.1 - 2.3e-13 50.5 0.0 3.6e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ion_trans PF00520.26 EGO58946.1 - 1.7e-05 24.1 20.4 3.5e-05 23.1 12.2 2.7 2 1 0 2 2 2 1 Ion transport protein PKD_channel PF08016.7 EGO58946.1 - 7.5e-05 21.3 10.0 0.019 13.4 0.3 2.2 1 1 1 2 2 2 2 Polycystin cation channel DUF3814 PF12769.2 EGO58946.1 - 0.0023 18.0 0.2 0.0061 16.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3814) Herpes_gE PF02480.11 EGO58947.1 - 0.00034 19.0 0.0 0.00066 18.0 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Podoplanin PF05808.6 EGO58947.1 - 0.0065 16.0 8.6 0.012 15.1 6.0 1.4 1 0 0 1 1 1 1 Podoplanin DUF566 PF04484.7 EGO58947.1 - 0.8 9.1 7.5 1.4 8.4 5.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) DJ-1_PfpI PF01965.19 EGO58948.1 - 6.7e-24 84.0 0.0 1.4e-23 82.9 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EGO58948.1 - 8.9e-20 69.9 0.1 2.1e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 EGO58948.1 - 0.045 13.0 0.0 0.2 10.9 0.0 2.1 1 1 0 1 1 1 0 Putative amidotransferase MMS1_N PF10433.4 EGO58950.1 - 1.7e-106 356.4 0.3 3.1e-106 355.4 0.2 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EGO58950.1 - 1.5e-67 227.9 0.0 1.1e-66 225.1 0.0 2.5 2 1 1 3 3 3 1 CPSF A subunit region Rieske PF00355.21 EGO58951.1 - 4.9e-18 64.4 0.0 8.3e-18 63.7 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 EGO58951.1 - 1.1e-17 63.9 1.3 2.1e-17 63.0 0.9 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region DUF2516 PF10724.4 EGO58951.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) HET PF06985.6 EGO58953.1 - 2.6e-24 85.9 0.1 5e-24 85.0 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) R3H-assoc PF13902.1 EGO58954.1 - 1.4e-23 83.3 0.2 1.4e-23 83.3 0.2 2.1 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.17 EGO58954.1 - 0.00069 19.2 0.0 0.0019 17.8 0.0 1.8 1 0 0 1 1 1 1 R3H domain PQ-loop PF04193.9 EGO58955.1 - 2.5e-21 74.9 14.0 9.1e-12 44.3 0.5 3.1 3 1 0 3 3 3 2 PQ loop repeat Pox_A14 PF05767.7 EGO58955.1 - 0.42 10.5 3.7 0.29 11.1 0.2 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 WD40 PF00400.27 EGO58956.1 - 2.9e-05 23.7 3.1 2.2 8.3 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Ammonium_transp PF00909.16 EGO58958.1 - 1.1e-67 228.2 26.2 1.3e-67 227.9 18.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Fungal_trans_2 PF11951.3 EGO58959.1 - 2e-19 69.4 1.0 3e-19 68.8 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO58959.1 - 1.2e-06 28.2 9.2 2.3e-06 27.3 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_binding_2 PF13380.1 EGO58960.1 - 3.5e-27 94.8 0.0 4.4e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 EGO58960.1 - 0.097 13.1 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain Methyltransf_11 PF08241.7 EGO58961.1 - 1.8e-19 69.9 0.0 2.9e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO58961.1 - 4.8e-15 56.1 0.1 9.1e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO58961.1 - 3.8e-12 46.4 0.0 6e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO58961.1 - 4.4e-11 43.1 0.0 6.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO58961.1 - 1.7e-08 34.3 0.0 3.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO58961.1 - 2.6e-08 33.5 0.0 4.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO58961.1 - 8.4e-08 32.2 0.2 2e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO58961.1 - 2.9e-06 26.5 0.0 4.2e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 EGO58961.1 - 0.00068 18.6 0.0 0.001 17.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 EGO58961.1 - 0.0061 15.9 0.0 0.0089 15.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 EGO58961.1 - 0.012 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) RrnaAD PF00398.15 EGO58961.1 - 0.037 13.0 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.6 EGO58961.1 - 0.068 11.8 0.0 0.098 11.3 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase CMAS PF02353.15 EGO58961.1 - 0.077 12.0 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EGO58961.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_7 PF13499.1 EGO58962.1 - 3e-15 56.1 0.2 1.7e-10 40.8 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EGO58962.1 - 8.3e-12 43.9 0.4 0.0007 19.2 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 EGO58962.1 - 9.1e-11 41.5 0.0 7.6e-05 22.5 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EGO58962.1 - 3.2e-10 38.5 0.5 0.011 15.0 0.0 4.1 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EGO58962.1 - 1.1e-07 31.3 1.1 0.0004 19.9 0.0 3.5 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EGO58962.1 - 0.025 13.9 1.2 2 7.8 0.7 3.2 3 0 0 3 3 3 0 EF hand DUF3216 PF11505.3 EGO58962.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Peptidase_M3 PF01432.15 EGO58963.1 - 9.6e-114 380.9 0.2 9.3e-113 377.6 0.1 2.0 1 1 0 1 1 1 1 Peptidase family M3 DUF2470 PF10615.4 EGO58963.1 - 0.005 17.0 0.2 0.015 15.4 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2470) APP_E2 PF12925.2 EGO58963.1 - 0.0089 15.6 0.1 0.023 14.2 0.1 1.7 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein Phage_GPO PF05929.6 EGO58963.1 - 0.084 12.1 0.0 0.27 10.4 0.0 1.8 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Aa_trans PF01490.13 EGO58966.1 - 5.9e-83 278.6 30.9 6.7e-83 278.4 21.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Tetraspannin PF00335.15 EGO58966.1 - 0.2 10.8 0.0 0.2 10.8 0.0 3.4 3 1 1 4 4 4 0 Tetraspanin family BIR PF00653.16 EGO58968.1 - 1.7e-22 79.6 0.3 4e-21 75.1 0.0 2.6 2 1 1 3 3 3 1 Inhibitor of Apoptosis domain LRR_9 PF14580.1 EGO58969.1 - 6.8e-48 162.5 0.1 1.1e-47 161.8 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EGO58969.1 - 3.5e-09 36.0 9.6 3e-06 26.7 0.3 3.9 2 2 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO58969.1 - 9.4e-08 31.7 4.5 1.1e-07 31.5 0.2 3.0 4 0 0 4 4 4 1 Leucine rich repeat LRR_7 PF13504.1 EGO58969.1 - 0.0024 17.7 3.3 0.91 10.0 0.0 4.4 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 EGO58969.1 - 0.0046 16.8 3.4 1.4 9.1 0.1 4.1 5 0 0 5 5 5 1 Leucine Rich repeat DUF4349 PF14257.1 EGO58969.1 - 0.0051 16.0 2.6 0.0087 15.3 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) LRR_1 PF00560.28 EGO58969.1 - 0.26 11.4 10.5 28 5.2 0.2 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat PspB PF06667.7 EGO58969.1 - 0.3 11.0 2.8 0.39 10.6 0.9 1.9 2 0 0 2 2 2 0 Phage shock protein B CBFD_NFYB_HMF PF00808.18 EGO58970.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Voltage_CLC PF00654.15 EGO58971.1 - 2.5e-90 303.0 28.2 2.5e-90 303.0 19.5 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EGO58971.1 - 9.6e-13 47.7 0.1 6e-06 25.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain DUF754 PF05449.6 EGO58971.1 - 1.7 8.7 6.7 0.17 11.9 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF754) DUF1900 PF08954.6 EGO58972.1 - 0.0071 15.8 0.0 3.4 7.1 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1900) CDO_I PF05995.7 EGO58973.1 - 5.7e-41 139.6 0.0 7.2e-41 139.2 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EGO58973.1 - 0.0001 21.7 0.2 0.00018 20.9 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) Pkinase PF00069.20 EGO58974.1 - 1.1e-24 87.0 0.0 1.6e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EGO58974.1 - 7.3e-14 51.0 7.8 7.7e-08 31.9 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.17 EGO58974.1 - 2.5e-10 39.5 6.4 0.16 12.0 0.1 6.9 7 0 0 7 7 7 3 HEAT repeat Pkinase_Tyr PF07714.12 EGO58974.1 - 6.3e-06 25.4 0.0 1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EGO58974.1 - 2.2e-05 24.6 2.4 0.15 12.3 0.3 4.5 2 1 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 EGO58974.1 - 0.012 16.1 8.6 0.022 15.2 0.1 4.7 5 1 1 6 6 6 0 HEAT-like repeat TFCD_C PF12612.3 EGO58974.1 - 0.039 13.3 0.1 0.095 12.1 0.0 1.6 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal Radical_SAM PF04055.16 EGO58977.1 - 2.7e-06 27.6 0.0 2.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily SH3_9 PF14604.1 EGO58978.1 - 2.7e-06 26.8 0.1 5.4e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO58978.1 - 0.00061 19.1 0.1 0.0013 18.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Adeno_E3_CR2 PF02439.10 EGO58978.1 - 0.0045 16.5 0.7 0.01 15.3 0.5 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF3112 PF11309.3 EGO58979.1 - 9.8e-50 168.4 18.4 4.4e-47 159.8 4.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) Metallophos PF00149.23 EGO58980.1 - 2.7e-44 150.9 0.9 3.5e-44 150.6 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Vps51 PF08700.6 EGO58981.1 - 2.4e-17 62.5 1.2 2.4e-17 62.5 0.8 2.8 3 0 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.6 EGO58981.1 - 1.5e-05 24.8 0.1 0.0064 16.3 0.0 2.5 2 0 0 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_B PF00052.13 EGO58981.1 - 0.008 15.7 0.4 0.055 13.0 0.2 2.2 1 1 1 2 2 2 1 Laminin B (Domain IV) MAS20 PF02064.10 EGO58982.1 - 7.7e-18 64.5 1.3 2.1e-17 63.1 0.9 1.6 1 1 0 1 1 1 1 MAS20 protein import receptor NAM-associated PF14303.1 EGO58982.1 - 0.2 11.9 3.3 0.27 11.5 2.3 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Gluconate_2-dh3 PF13618.1 EGO58982.1 - 1.1 9.4 5.1 2.6 8.1 3.5 1.7 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Wyosine_form PF08608.7 EGO58983.1 - 5.6e-25 87.2 0.0 2e-24 85.4 0.0 2.0 2 0 0 2 2 2 1 Wyosine base formation Radical_SAM PF04055.16 EGO58983.1 - 2.1e-21 76.7 0.0 4.5e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.20 EGO58983.1 - 2.5e-08 34.0 0.1 1.6e-06 28.1 0.1 2.6 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.2 EGO58983.1 - 0.083 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain EamA PF00892.15 EGO58984.1 - 0.0089 16.0 8.3 0.01 15.8 5.2 1.5 1 1 0 1 1 1 1 EamA-like transporter family UPF0546 PF10639.4 EGO58984.1 - 0.13 12.1 2.6 0.18 11.6 1.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 EmrE PF13536.1 EGO58984.1 - 0.18 12.0 10.2 0.029 14.5 4.1 1.6 1 1 0 1 1 1 0 Multidrug resistance efflux transporter Ca_hom_mod PF14798.1 EGO58984.1 - 2.6 6.9 5.6 0.61 9.0 1.8 1.4 2 0 0 2 2 2 0 Calcium homeostasis modulator TFIIA_gamma_C PF02751.9 EGO58985.1 - 2e-26 91.5 1.4 2.8e-26 91.0 1.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EGO58985.1 - 2.3e-24 84.7 0.2 3.3e-24 84.2 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain MoCF_biosynth PF00994.19 EGO58986.1 - 1.4e-55 186.6 1.4 3.9e-31 107.3 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EGO58986.1 - 5.5e-31 107.1 6.4 3.5e-30 104.4 4.4 2.1 1 1 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EGO58986.1 - 1.1e-14 54.1 0.0 3.2e-14 52.6 0.0 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) ATP_bind_1 PF03029.12 EGO58987.1 - 2.7e-69 233.3 0.1 4.5e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein WD40 PF00400.27 EGO58988.1 - 7.3e-27 92.2 0.9 7e-08 32.0 0.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat RRM_1 PF00076.17 EGO58990.1 - 5.2e-25 86.8 0.0 5.6e-12 45.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO58990.1 - 6.2e-17 61.3 0.0 8.2e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO58990.1 - 7.6e-08 32.0 0.0 0.0042 16.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4586 PF15239.1 EGO58990.1 - 0.046 13.2 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4586) FAD_binding_1 PF00667.15 EGO58991.1 - 1.7e-59 200.8 0.0 2.6e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EGO58991.1 - 2.5e-33 115.0 1.0 5.8e-33 113.8 0.7 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EGO58991.1 - 5.3e-21 75.2 0.1 7.6e-20 71.5 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EGO58991.1 - 0.013 15.4 0.0 0.038 13.9 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain MOR2-PAG1_N PF14222.1 EGO58992.1 - 8.2e-211 701.4 0.7 2.2e-210 700.0 0.1 1.8 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EGO58992.1 - 4e-95 318.5 0.3 9.6e-95 317.2 0.2 1.7 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EGO58992.1 - 4.8e-39 133.7 7.2 6.3e-18 63.8 0.1 3.5 2 1 1 3 3 3 3 Cell morphogenesis central region NPH3 PF03000.9 EGO58992.1 - 0.029 13.9 0.1 0.11 12.0 0.0 2.0 1 0 0 1 1 1 0 NPH3 family Zn_clus PF00172.13 EGO58993.1 - 1.8e-07 30.9 8.2 3.2e-07 30.1 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGO58993.1 - 0.0023 16.5 0.0 0.0058 15.2 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pox_F17 PF04767.7 EGO58993.1 - 0.08 13.2 1.0 0.15 12.3 0.7 1.4 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein TauD PF02668.11 EGO58994.1 - 8.6e-48 163.2 0.3 1.6e-47 162.3 0.2 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1237 PF06824.6 EGO58995.1 - 9.6e-171 568.0 0.1 1.2e-170 567.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) FAD-SLDH PF12318.3 EGO58995.1 - 0.0047 16.6 0.2 0.57 9.8 0.0 2.3 2 0 0 2 2 2 2 Membrane bound FAD containing D-sorbitol dehydrogenase Clr2 PF10383.4 EGO58996.1 - 6.3e-29 100.7 0.0 6.3e-29 100.7 0.0 2.6 2 1 0 2 2 1 1 Transcription-silencing protein Clr2 Ycf1 PF05758.7 EGO58996.1 - 0.0068 14.1 9.3 0.0086 13.8 6.4 1.1 1 0 0 1 1 1 1 Ycf1 Spore_coat_CotO PF14153.1 EGO58996.1 - 0.0076 15.7 20.7 0.011 15.2 14.4 1.2 1 0 0 1 1 1 1 Spore coat protein CotO LMBR1 PF04791.11 EGO58996.1 - 0.026 13.1 1.6 0.032 12.8 1.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HlyD_2 PF12700.2 EGO58996.1 - 0.039 13.1 12.9 0.056 12.6 8.9 1.2 1 0 0 1 1 1 0 HlyD family secretion protein PA26 PF04636.8 EGO58996.1 - 0.05 12.3 9.8 0.071 11.7 6.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Pex14_N PF04695.8 EGO58996.1 - 0.22 11.5 19.7 0.4 10.7 13.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mem_trans PF03547.13 EGO58996.1 - 0.22 9.7 0.2 0.23 9.7 0.1 1.1 1 0 0 1 1 1 0 Membrane transport protein OmpH PF03938.9 EGO58996.1 - 0.62 9.9 43.1 1.2 9.0 29.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FAM222A PF15258.1 EGO58996.1 - 0.76 8.9 28.1 1.4 8.0 19.5 1.4 1 0 0 1 1 1 0 Protein family of FAM222A PIH1 PF08190.7 EGO58996.1 - 1.9 7.8 23.6 3.4 7.0 16.3 1.3 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Hid1 PF12722.2 EGO58996.1 - 1.9 6.0 18.8 2.5 5.6 13.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AvrE PF11725.3 EGO58996.1 - 1.9 5.3 21.3 2.5 4.9 14.8 1.0 1 0 0 1 1 1 0 Pathogenicity factor DUF2201_N PF13203.1 EGO58996.1 - 2.2 7.3 19.0 3.6 6.6 13.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain AUX_IAA PF02309.11 EGO58996.1 - 2.5 7.8 15.5 4.4 6.9 10.8 1.4 1 0 0 1 1 1 0 AUX/IAA family PAT1 PF09770.4 EGO58996.1 - 7.1 4.7 51.7 10 4.2 35.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 VIT1 PF01988.14 EGO58996.1 - 9.4 5.6 6.5 15 5.0 4.5 1.3 1 0 0 1 1 1 0 VIT family adh_short PF00106.20 EGO58998.1 - 1.3e-14 54.5 0.4 2.6e-14 53.4 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGO58998.1 - 1.5e-05 24.7 0.1 4.6e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EGO58998.1 - 0.0088 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Toprim_3 PF13362.1 EGO58998.1 - 0.071 13.3 0.5 0.16 12.2 0.4 1.5 1 0 0 1 1 1 0 Toprim domain SUN PF03856.8 EGO59000.1 - 4.1e-77 258.8 13.2 5.4e-77 258.4 9.2 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Thiolase_N PF00108.18 EGO59002.1 - 8.4e-95 316.7 0.5 1.3e-94 316.0 0.4 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGO59002.1 - 9.2e-39 131.6 0.7 9.2e-39 131.6 0.5 2.1 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGO59002.1 - 6.2e-05 22.6 2.0 0.0028 17.1 0.4 2.7 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain UQ_con PF00179.21 EGO59003.1 - 6.3e-52 174.7 0.0 7.2e-52 174.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO59003.1 - 8.1e-07 28.8 0.0 9.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGO59003.1 - 0.025 14.4 0.2 0.058 13.2 0.1 1.6 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.18 EGO59005.1 - 4.4e-113 377.3 0.1 4.4e-113 377.3 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain 4HBT PF03061.17 EGO59007.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily Asp PF00026.18 EGO59008.1 - 2.2e-09 37.0 2.0 2.5e-08 33.5 1.4 2.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Phage_stabilise PF11134.3 EGO59008.1 - 0.15 10.6 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Phage stabilisation protein FAD_binding_1 PF00667.15 EGO59010.1 - 7.8e-29 100.6 0.0 7.9e-28 97.3 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 EGO59010.1 - 3.2e-12 46.6 0.0 1.1e-11 44.9 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EGO59010.1 - 2.1e-10 41.1 0.0 1.2e-08 35.4 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain RRM_1 PF00076.17 EGO59011.1 - 5.2e-31 106.0 0.1 5e-15 54.8 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO59011.1 - 1.2e-24 86.0 0.0 1.8e-12 47.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO59011.1 - 8.1e-09 35.2 0.0 0.0014 18.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 EGO59011.1 - 0.0023 16.4 2.1 0.0035 15.9 1.5 1.2 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) DbpA PF03880.10 EGO59011.1 - 0.078 12.6 0.2 9 6.0 0.0 2.6 3 0 0 3 3 3 0 DbpA RNA binding domain Limkain-b1 PF11608.3 EGO59011.1 - 0.087 12.5 0.6 13 5.5 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 ArfGap PF01412.13 EGO59012.1 - 1.4e-33 115.1 0.2 2.4e-33 114.3 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF2518 PF10726.4 EGO59012.1 - 0.17 11.4 0.6 1.1 8.7 0.4 1.9 2 0 0 2 2 2 0 Protein of function (DUF2518) zf-UBR PF02207.15 EGO59012.1 - 0.38 10.5 3.4 3.4 7.4 1.1 2.2 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) ETF PF01012.16 EGO59013.1 - 1.1e-36 125.9 0.6 1.5e-36 125.6 0.4 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain GATase PF00117.23 EGO59014.1 - 7.1e-47 159.3 0.0 1.1e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EGO59014.1 - 1.2e-46 157.4 0.0 2e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 EGO59014.1 - 2.5e-06 27.0 0.1 0.00037 19.9 0.1 2.7 1 1 0 1 1 1 1 Peptidase C26 SAP PF02037.22 EGO59015.1 - 2.2e-13 49.3 0.8 4.6e-13 48.3 0.6 1.5 1 0 0 1 1 1 1 SAP domain DUF1379 PF07126.7 EGO59016.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1379) GATA PF00320.22 EGO59017.1 - 8.8e-32 108.1 15.1 7.6e-17 60.3 2.1 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EGO59017.1 - 2.8e-06 26.5 1.5 0.017 14.4 0.0 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EGO59017.1 - 0.0003 19.8 4.4 0.25 10.5 0.3 2.8 2 0 0 2 2 2 2 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EGO59017.1 - 0.00082 18.9 3.6 0.07 12.7 0.3 2.7 2 0 0 2 2 2 2 Putative transposase DNA-binding domain ArfGap PF01412.13 EGO59017.1 - 0.0044 16.7 2.7 0.56 10.0 0.1 2.6 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.5 EGO59017.1 - 0.0063 16.4 1.3 0.84 9.6 0.1 2.7 2 0 0 2 2 2 1 Zinc ribbon domain RRN7 PF11781.3 EGO59017.1 - 0.018 14.5 0.5 0.018 14.5 0.3 2.6 3 0 0 3 3 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 EGO59017.1 - 0.023 14.5 13.3 2.4 8.0 3.3 3.2 1 1 1 2 2 2 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 EGO59017.1 - 0.045 13.3 0.5 0.045 13.3 0.3 2.9 3 0 0 3 3 2 0 Sec23/Sec24 zinc finger COX5B PF01215.14 EGO59017.1 - 0.08 12.6 0.5 0.93 9.1 0.1 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Vb Auto_anti-p27 PF06677.7 EGO59017.1 - 0.19 11.5 3.6 5.2 6.9 0.2 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-CHY PF05495.7 EGO59017.1 - 0.28 11.3 2.2 3.4 7.9 0.1 2.6 2 0 0 2 2 2 0 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 EGO59017.1 - 0.59 9.9 6.6 1.3 8.8 0.7 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain HypA PF01155.14 EGO59017.1 - 1.6 8.4 6.8 1.3 8.7 0.1 2.8 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family eIF-5_eIF-2B PF01873.12 EGO59017.1 - 3.1 7.4 8.2 6.1 6.5 0.5 2.7 3 0 0 3 3 3 0 Domain found in IF2B/IF5 Ribosomal_L32p PF01783.18 EGO59017.1 - 4.5 7.5 13.7 4.1 7.6 1.4 4.8 3 2 0 3 3 3 0 Ribosomal L32p protein family COPI_assoc PF08507.5 EGO59018.1 - 3.9e-46 156.1 5.1 4.3e-46 156.0 3.5 1.0 1 0 0 1 1 1 1 COPI associated protein DUF1212 PF06738.7 EGO59018.1 - 5.8 6.3 7.6 7.5 5.9 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) YrhC PF14143.1 EGO59018.1 - 8 6.4 8.8 0.63 10.0 0.8 2.3 2 1 0 2 2 2 0 YrhC-like protein BCIP PF13862.1 EGO59019.1 - 1.5e-64 217.1 0.3 1.9e-64 216.7 0.2 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein CM_2 PF01817.16 EGO59020.1 - 6e-05 23.0 0.0 9.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Chorismate mutase type II WD40 PF00400.27 EGO59021.1 - 4.3e-41 137.3 5.4 5.2e-10 38.8 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EGO59021.1 - 3.4e-06 25.5 8.8 0.08 11.0 0.2 4.6 2 2 2 5 5 5 4 Nucleoporin Nup120/160 APG6 PF04111.7 EGO59021.1 - 0.07 12.1 3.1 0.11 11.5 2.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EGO59021.1 - 0.21 11.1 2.5 0.33 10.5 1.8 1.2 1 0 0 1 1 1 0 IncA protein XhlA PF10779.4 EGO59021.1 - 7.1 6.6 7.0 2.2 8.2 2.6 1.8 2 0 0 2 2 2 0 Haemolysin XhlA Aldo_ket_red PF00248.16 EGO59022.1 - 7.3e-65 218.5 0.0 8.3e-65 218.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1279 PF06916.8 EGO59022.1 - 0.0048 17.1 0.1 0.011 16.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DNA_pol3_tau_4 PF12168.3 EGO59022.1 - 0.18 12.2 2.2 0.31 11.4 1.5 1.3 1 0 0 1 1 1 0 DNA polymerase III subunits tau domain IV DnaB-binding RIO1 PF01163.17 EGO59023.1 - 5.7e-41 139.9 0.5 1.5e-28 99.4 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 EGO59023.1 - 3.1e-31 107.2 0.0 8e-31 105.9 0.0 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EGO59023.1 - 5.3e-08 32.8 0.1 0.00019 21.2 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGO59023.1 - 5.2e-05 22.4 0.0 0.085 11.9 0.0 2.4 1 1 1 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_27 PF13463.1 EGO59023.1 - 0.016 15.5 0.0 0.05 13.9 0.0 1.9 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF2457 PF10446.4 EGO59023.1 - 0.035 12.8 17.4 0.052 12.2 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 EGO59023.1 - 0.039 11.8 12.2 0.046 11.6 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.3 EGO59023.1 - 0.088 12.7 14.8 0.17 11.8 10.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Striatin PF08232.7 EGO59023.1 - 0.18 12.1 5.0 0.74 10.1 3.4 1.9 2 0 0 2 2 2 0 Striatin family RXT2_N PF08595.6 EGO59023.1 - 0.32 10.7 7.5 0.85 9.4 5.2 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4611 PF15387.1 EGO59023.1 - 0.42 10.7 12.0 1.1 9.4 8.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.8 EGO59023.1 - 0.68 7.6 20.9 1 7.0 14.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Vfa1 PF08432.5 EGO59023.1 - 0.91 9.5 9.7 1.7 8.6 6.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 EGO59023.1 - 3.9 5.8 16.0 5.2 5.4 11.1 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EGO59023.1 - 4 5.3 12.6 6.3 4.7 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EGO59023.1 - 4 6.7 12.1 7.1 5.9 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NOA36 PF06524.7 EGO59023.1 - 4.6 6.3 9.7 6.9 5.8 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.7 EGO59023.1 - 5 6.7 16.2 9.9 5.7 11.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.6 EGO59023.1 - 9.4 3.9 9.7 13 3.4 6.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PC_rep PF01851.17 EGO59024.1 - 7e-24 82.6 15.1 7.1e-05 22.8 0.1 9.4 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EGO59024.1 - 3.1e-09 36.9 1.8 0.0012 19.1 0.0 5.1 6 0 0 6 6 6 2 HEAT repeats Wx5_PLAF3D7 PF09688.5 EGO59024.1 - 2.6 8.0 5.6 1.9 8.4 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) MatE PF01554.13 EGO59025.1 - 2.6e-59 199.4 29.7 7.2e-30 103.7 8.0 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EGO59025.1 - 0.0017 18.1 10.4 0.0017 18.1 7.2 3.9 4 0 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain NUDIX PF00293.23 EGO59026.1 - 7.7e-30 103.2 0.0 1.1e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_7 PF13508.1 EGO59027.1 - 8.7e-09 35.4 0.0 1.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGO59027.1 - 3.8e-06 26.7 0.0 7.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO59027.1 - 3.9e-06 26.7 0.0 8.5e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGO59027.1 - 0.00071 19.6 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGO59027.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 EGO59027.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein RPA_C PF08784.6 EGO59028.1 - 3.7e-31 107.5 1.2 4.6e-31 107.2 0.1 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EGO59028.1 - 4.8e-07 29.5 0.2 8.7e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF202 PF02656.10 EGO59029.1 - 5.1e-20 71.4 0.1 7.6e-20 70.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.7 EGO59029.1 - 0.0019 18.1 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial aa3 type cytochrome c oxidase subunit IV Arm PF00514.18 EGO59031.1 - 0.014 15.1 0.4 8.9 6.3 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EGO59031.1 - 0.024 15.1 0.8 23 5.6 0.0 3.8 2 0 0 2 2 2 0 HEAT-like repeat Daxx PF03344.10 EGO59031.1 - 0.27 9.6 20.9 0.49 8.8 14.5 1.3 1 0 0 1 1 1 0 Daxx Family PBP_sp32 PF07222.7 EGO59031.1 - 1.2 8.2 6.2 29 3.7 3.4 2.3 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Astro_capsid PF03115.9 EGO59031.1 - 2 6.5 9.9 3.2 5.8 6.9 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF2457 PF10446.4 EGO59031.1 - 2.2 6.9 26.2 4.1 6.0 18.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.5 EGO59031.1 - 3.9 6.4 21.5 0.5 9.3 12.0 1.5 2 0 0 2 2 2 0 BUD22 DnaJ PF00226.26 EGO59032.1 - 9.5e-12 44.4 0.5 3.2e-11 42.8 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain DUF3625 PF12293.3 EGO59032.1 - 0.017 14.2 0.1 0.077 12.1 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3625) CP12 PF02672.10 EGO59032.1 - 2.2 8.8 10.7 6.3 7.3 0.2 2.8 2 0 0 2 2 2 0 CP12 domain Nitroreductase PF00881.19 EGO59032.1 - 6.2 6.6 7.0 22 4.8 0.1 2.2 1 1 1 2 2 2 0 Nitroreductase family DEAD PF00270.24 EGO59033.1 - 7.2e-45 152.5 0.0 4.6e-44 149.8 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase DBP10CT PF08147.7 EGO59033.1 - 2.6e-22 78.4 2.8 6.8e-22 77.0 1.9 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 EGO59033.1 - 1.3e-21 76.1 0.1 3.5e-21 74.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGO59033.1 - 0.00041 19.2 0.0 0.00069 18.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4137 PF13593.1 EGO59033.1 - 0.23 10.4 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) Na_Ca_ex PF01699.19 EGO59034.1 - 8.7e-39 132.3 21.9 8.7e-22 77.2 6.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3608 PF12257.3 EGO59035.1 - 2.6e-73 246.3 0.0 4.7e-73 245.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EGO59035.1 - 8.4e-29 99.1 0.1 2e-28 97.8 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Zip PF02535.17 EGO59035.1 - 0.0099 14.9 3.0 0.018 14.0 2.1 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter CPSF73-100_C PF11718.3 EGO59035.1 - 5.6 6.2 3.7 11 5.2 2.6 1.4 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Cation_efflux PF01545.16 EGO59036.1 - 4.8e-33 114.4 0.3 6.3e-33 114.0 0.2 1.1 1 0 0 1 1 1 1 Cation efflux family Keratin_B2_2 PF13885.1 EGO59036.1 - 9.5 6.0 10.9 60 3.4 7.6 1.9 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein CMV_US PF08001.6 EGO59037.1 - 0.043 12.8 0.1 0.053 12.5 0.1 1.4 1 1 0 1 1 1 0 CMV US FNIP_N PF14636.1 EGO59039.1 - 8.3e-25 87.7 0.9 8.3e-25 87.7 0.7 4.2 4 1 1 5 5 5 1 Folliculin-interacting protein N-terminus FNIP_C PF14638.1 EGO59039.1 - 0.0026 17.1 0.0 0.0054 16.0 0.0 1.4 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus C9orf72-like PF15019.1 EGO59039.1 - 0.016 14.4 0.1 6.4 5.9 0.0 2.8 3 0 0 3 3 3 0 C9orf72-like protein family Fungal_trans PF04082.13 EGO59041.1 - 4.1e-10 38.9 0.1 4.1e-10 38.9 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO59041.1 - 3.8e-09 36.3 7.9 3.8e-09 36.3 5.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactonase PF10282.4 EGO59043.1 - 1.4e-84 284.1 0.0 1.6e-84 283.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Solute_trans_a PF03619.11 EGO59046.1 - 7.5e-106 353.4 4.7 9e-106 353.1 3.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha GTP_EFTU PF00009.22 EGO59047.1 - 1.8e-62 210.1 0.1 2.6e-62 209.6 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGO59047.1 - 2.1e-37 127.3 0.0 5.9e-37 125.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EGO59047.1 - 1e-21 76.5 0.0 3.1e-21 75.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGO59047.1 - 2e-12 47.0 1.1 6.2e-12 45.4 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EGO59047.1 - 2.6e-12 46.3 0.0 7.3e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EGO59047.1 - 1.4e-05 25.0 0.2 3e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EGO59047.1 - 0.076 12.5 0.1 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RRM_6 PF14259.1 EGO59048.1 - 2.8e-12 46.4 0.1 8.2e-12 44.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO59048.1 - 5.6e-09 35.7 0.2 1.6e-08 34.2 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO59048.1 - 1.5e-07 30.9 1.0 1.5e-06 27.7 0.1 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EGO59048.1 - 1e-06 28.7 0.0 2.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.19 EGO59048.1 - 6.3e-05 22.5 4.1 0.00012 21.6 2.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.1 EGO59048.1 - 6.5e-05 22.6 0.0 0.0088 15.7 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Borrelia_P83 PF05262.6 EGO59048.1 - 0.21 9.7 3.7 0.29 9.3 2.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_M16 PF00675.15 EGO59048.1 - 0.56 9.9 3.3 7.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Nop25 PF09805.4 EGO59048.1 - 3.2 7.8 16.9 0.14 12.2 7.7 1.6 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Sec5 PF15469.1 EGO59049.1 - 1.6e-33 115.9 0.0 9.4e-33 113.4 0.0 2.3 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.6 EGO59049.1 - 1.5e-05 24.7 0.4 0.00022 21.0 0.0 3.0 2 0 0 2 2 2 1 Vps51/Vps67 DUF3572 PF12096.3 EGO59049.1 - 0.081 12.7 0.4 0.21 11.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3572) Iso_dh PF00180.15 EGO59050.1 - 1.7e-98 329.8 0.0 1.9e-98 329.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF3774 PF12609.3 EGO59051.1 - 0.086 13.6 4.1 0.13 13.1 2.9 1.3 1 0 0 1 1 1 0 Wound-induced protein SR-25 PF10500.4 EGO59051.1 - 0.21 11.0 8.8 0.19 11.1 6.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.18 EGO59052.1 - 0.026 14.4 0.6 0.043 13.7 0.0 1.7 2 0 0 2 2 2 0 Zinc knuckle DUF3485 PF11984.3 EGO59053.1 - 0.017 14.2 0.0 0.03 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) BSP PF04450.7 EGO59054.1 - 6.9e-75 251.0 0.0 8.4e-75 250.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EGO59054.1 - 4e-06 26.9 0.5 0.00011 22.2 0.3 2.1 1 1 0 1 1 1 1 Peptidase MA superfamily CLASP_N PF12348.3 EGO59055.1 - 4e-136 451.6 4.5 9.9e-92 306.3 0.1 3.2 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 EGO59055.1 - 4.7e-06 26.2 0.4 2.3 8.4 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EGO59055.1 - 0.00015 21.9 1.0 0.36 11.1 0.0 4.6 3 2 2 5 5 5 1 HEAT repeats Vac14_Fab1_bd PF12755.2 EGO59055.1 - 0.0012 19.1 0.0 2.6 8.5 0.0 3.7 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EGO59055.1 - 0.013 15.9 3.6 0.6 10.6 0.0 3.9 4 0 0 4 4 4 0 HEAT-like repeat zf-BED PF02892.10 EGO59056.1 - 0.0053 16.4 1.3 0.021 14.6 0.4 2.2 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_6 PF13912.1 EGO59056.1 - 0.29 11.0 5.6 0.068 13.0 0.5 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger DUF676 PF05057.9 EGO59057.1 - 9.8e-46 155.7 0.1 1.5e-29 102.9 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EGO59057.1 - 0.007 15.9 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 EGO59057.1 - 0.015 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) MTHFR PF02219.12 EGO59058.1 - 2.7e-114 381.1 0.0 4.4e-114 380.4 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Methyltransf_31 PF13847.1 EGO59058.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RhoGAP PF00620.22 EGO59059.1 - 3.9e-48 162.9 1.9 8.2e-48 161.8 0.1 2.3 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EGO59059.1 - 9.3e-14 51.2 18.5 5.4e-09 35.9 1.6 2.4 2 0 0 2 2 2 2 LIM domain Uteroglobin PF01099.12 EGO59059.1 - 0.074 12.8 1.6 0.14 11.9 0.2 2.1 2 0 0 2 2 2 0 Uteroglobin family Zn-ribbon_8 PF09723.5 EGO59059.1 - 0.56 10.2 16.5 0.48 10.4 0.7 4.0 4 0 0 4 4 4 0 Zinc ribbon domain zf-C3HC4_3 PF13920.1 EGO59059.1 - 8.4 6.1 18.0 0.74 9.5 3.6 3.2 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) rRNA_processing PF08524.6 EGO59060.1 - 0.00054 19.7 34.4 0.048 13.4 7.9 3.0 2 1 0 2 2 2 2 rRNA processing Inhibitor_I71 PF12628.2 EGO59060.1 - 2.9 7.5 5.9 0.87 9.2 0.2 2.4 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor DUF4210 PF13915.1 EGO59061.1 - 2.2e-25 88.6 0.0 4.4e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EGO59061.1 - 4e-23 81.0 0.7 1.1e-22 79.6 0.5 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis Npa1 PF11707.3 EGO59062.1 - 3.9e-87 292.3 0.0 6.9e-87 291.5 0.0 1.4 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Creb_binding PF09030.5 EGO59062.1 - 0.0064 16.6 0.0 0.054 13.6 0.0 2.6 2 0 0 2 2 2 1 Creb binding DUF1670 PF07900.6 EGO59062.1 - 0.11 11.7 0.1 0.24 10.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) PPR_3 PF13812.1 EGO59064.1 - 4.4e-09 35.9 0.3 0.044 14.0 0.0 7.1 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EGO59064.1 - 8.8e-09 35.2 0.0 0.07 13.1 0.0 6.1 5 2 2 7 7 7 2 PPR repeat family PPR PF01535.15 EGO59064.1 - 1.5e-06 27.8 0.2 1.1 9.3 0.0 4.9 5 0 0 5 5 5 2 PPR repeat PPR_1 PF12854.2 EGO59064.1 - 0.076 12.5 4.7 37 3.9 0.0 5.0 5 0 0 5 5 5 0 PPR repeat Malate_synthase PF01274.17 EGO59064.1 - 0.086 10.8 0.0 0.14 10.0 0.0 1.3 1 0 0 1 1 1 0 Malate synthase LSM PF01423.17 EGO59065.1 - 9e-16 57.1 0.1 1.2e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain GRP PF07172.6 EGO59065.1 - 0.72 10.3 22.1 0.93 10.0 15.3 1.3 1 0 0 1 1 1 0 Glycine rich protein family BAR_2 PF10455.4 EGO59066.1 - 2.3e-59 200.7 0.5 3.2e-59 200.2 0.3 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EGO59066.1 - 2.9e-20 72.7 3.5 5.6e-19 68.5 2.4 2.0 1 1 0 1 1 1 1 BAR domain DUF3437 PF11919.3 EGO59066.1 - 0.058 13.1 0.5 0.33 10.7 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) IQ-like PF15157.1 EGO59066.1 - 0.18 12.0 1.7 0.65 10.2 0.0 2.8 3 1 1 4 4 4 0 IQ-like DUF619 PF04768.8 EGO59067.1 - 9e-52 174.9 0.0 5.3e-51 172.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF619) DUF2065 PF09838.4 EGO59067.1 - 0.13 12.0 0.1 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) NAD_binding_2 PF03446.10 EGO59068.1 - 3e-30 105.2 0.1 4.8e-30 104.5 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EGO59068.1 - 2.7e-07 30.6 0.0 4.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EGO59068.1 - 5e-06 26.8 0.6 1.3e-05 25.5 0.1 1.9 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EGO59068.1 - 4.4e-05 23.6 0.1 8.4e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGO59068.1 - 0.034 13.5 0.3 0.097 12.0 0.2 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UPF0228 PF05727.6 EGO59068.1 - 0.12 12.1 0.3 0.21 11.3 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0228) Arv1 PF04161.8 EGO59069.1 - 2.5e-34 119.0 2.4 4e-23 82.4 0.2 2.1 1 1 1 2 2 2 2 Arv1-like family LysM PF01476.15 EGO59069.1 - 0.005 16.7 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 LysM domain Xylo_C PF12529.3 EGO59069.1 - 0.21 10.9 0.0 0.4 10.0 0.0 1.3 1 0 0 1 1 1 0 Xylosyltransferase C terminal SMC_N PF02463.14 EGO59070.1 - 4.7e-70 235.2 8.5 1.1e-38 132.6 0.1 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGO59070.1 - 5.3e-24 84.4 0.3 7e-23 80.8 0.1 3.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EGO59070.1 - 3.1e-14 53.6 0.3 4.1e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain MscS_porin PF12795.2 EGO59070.1 - 7.5e-05 22.1 33.3 7.5e-05 22.1 23.1 6.5 5 1 2 7 7 7 2 Mechanosensitive ion channel porin domain AAA_29 PF13555.1 EGO59070.1 - 8.5e-05 22.0 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2316 PF10078.4 EGO59070.1 - 0.012 15.5 1.9 0.012 15.5 1.3 4.6 5 0 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2316) ABC_tran PF00005.22 EGO59070.1 - 0.097 12.9 0.0 0.097 12.9 0.0 6.1 2 2 1 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 EGO59070.1 - 0.3 10.2 33.3 0.38 9.8 0.3 5.9 3 2 4 7 7 7 0 Reovirus sigma C capsid protein PASTA PF03793.14 EGO59070.1 - 1.5 8.4 7.7 17 5.1 0.0 4.7 5 0 0 5 5 5 0 PASTA domain Fungal_trans_2 PF11951.3 EGO59073.1 - 1e-14 53.9 1.1 1.7e-14 53.2 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO59073.1 - 3.2e-08 33.3 10.2 6.1e-08 32.4 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mob1_phocein PF03637.12 EGO59074.1 - 3.4e-25 88.7 3.7 5.6e-25 88.0 2.6 1.2 1 0 0 1 1 1 1 Mob1/phocein family cobW PF02492.14 EGO59075.1 - 1.6e-44 151.4 0.4 2.1e-44 151.0 0.2 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EGO59075.1 - 0.00034 20.2 0.0 0.0008 19.0 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain ATP_bind_1 PF03029.12 EGO59075.1 - 0.0091 15.5 0.2 0.35 10.3 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EGO59075.1 - 0.013 15.3 0.5 0.049 13.5 0.4 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_19 PF13245.1 EGO59075.1 - 0.014 15.0 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 EGO59075.1 - 0.016 14.0 1.2 1.4 7.5 0.0 2.7 3 0 0 3 3 3 0 ArgK protein Miro PF08477.8 EGO59075.1 - 0.019 15.4 0.2 0.25 11.8 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_18 PF13238.1 EGO59075.1 - 0.02 15.1 0.6 0.062 13.6 0.1 2.1 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.1 EGO59075.1 - 0.024 14.9 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGO59075.1 - 0.029 14.5 0.3 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 EGO59075.1 - 0.033 13.2 0.7 3.9 6.4 0.1 2.2 2 0 0 2 2 2 0 Septin Arch_ATPase PF01637.13 EGO59075.1 - 0.036 13.7 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase GTP_EFTU PF00009.22 EGO59075.1 - 0.04 13.3 2.5 0.77 9.1 1.8 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EGO59075.1 - 0.043 13.2 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 EGO59075.1 - 0.057 12.5 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin DUF258 PF03193.11 EGO59075.1 - 0.067 12.3 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGO59075.1 - 0.078 12.5 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EGO59075.1 - 0.085 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 EGO59075.1 - 0.091 12.6 0.1 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGO59075.1 - 0.16 11.5 1.0 1.8 8.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain NOT2_3_5 PF04153.13 EGO59076.1 - 1.9e-34 118.4 1.5 2.7e-34 117.9 1.0 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CUE PF02845.11 EGO59078.1 - 2e-13 49.5 0.0 3e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain TMEM171 PF15471.1 EGO59078.1 - 0.11 11.2 1.8 0.16 10.7 1.3 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 zf-C4H2 PF10146.4 EGO59078.1 - 0.13 12.2 0.8 0.23 11.4 0.5 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein DUF737 PF05300.6 EGO59078.1 - 0.81 9.6 7.4 5.4 6.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Neur_chan_memb PF02932.11 EGO59079.1 - 0.044 13.6 0.0 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Myc_N PF01056.13 EGO59079.1 - 0.12 11.5 1.0 0.17 11.0 0.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.14 EGO59079.1 - 0.19 12.1 6.7 0.37 11.2 4.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DEAD PF00270.24 EGO59080.1 - 1.4e-42 145.0 0.2 3.5e-42 143.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO59080.1 - 7.6e-21 73.7 0.1 2e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO59080.1 - 0.0061 16.4 0.0 0.0099 15.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UBA_2 PF08587.6 EGO59080.1 - 0.089 12.9 0.1 0.24 11.5 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Fungal_trans PF04082.13 EGO59081.1 - 1.1e-26 93.2 0.0 1.1e-26 93.2 0.0 1.8 2 0 0 2 2 1 1 Fungal specific transcription factor domain Baculo_PP31 PF05311.6 EGO59081.1 - 0.00039 19.7 2.3 0.00067 19.0 1.6 1.4 1 0 0 1 1 1 1 Baculovirus 33KDa late protein (PP31) Borrelia_P83 PF05262.6 EGO59081.1 - 0.13 10.5 10.8 0.19 9.9 7.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Ycf1 PF05758.7 EGO59081.1 - 0.36 8.5 11.4 0.5 8.0 7.9 1.1 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 EGO59081.1 - 0.38 8.3 19.5 0.59 7.7 13.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-DHHC PF01529.15 EGO59081.1 - 0.74 9.1 3.8 0.17 11.3 0.2 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase DDHD PF02862.12 EGO59081.1 - 1.9 8.2 16.3 4.9 6.8 11.3 1.6 1 0 0 1 1 1 0 DDHD domain SAGA-Tad1 PF12767.2 EGO59081.1 - 2.9 7.4 27.2 0.36 10.4 12.6 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit AUX_IAA PF02309.11 EGO59081.1 - 3.4 7.3 15.1 8.1 6.1 10.5 1.6 1 0 0 1 1 1 0 AUX/IAA family AAA_23 PF13476.1 EGO59081.1 - 4 7.7 19.2 0.11 12.7 8.8 1.7 2 0 0 2 2 1 0 AAA domain Zip PF02535.17 EGO59081.1 - 5.6 5.8 7.3 12 4.8 5.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter TOM13 PF08219.6 EGO59082.1 - 0.017 14.8 0.2 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 Outer membrane protein TOM13 MFS_1 PF07690.11 EGO59083.1 - 5e-33 114.2 17.8 5e-33 114.2 12.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO59083.1 - 3.4e-08 32.5 4.7 3.4e-08 32.5 3.3 2.7 2 2 1 3 3 3 1 Sugar (and other) transporter DUF1014 PF06244.7 EGO59086.1 - 1.1e-23 83.7 2.5 1.1e-23 83.7 1.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1014) DUF719 PF05334.8 EGO59086.1 - 0.065 13.2 0.6 0.57 10.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) UQ_con PF00179.21 EGO59087.1 - 5.5e-11 42.0 0.1 1.1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BRE PF06113.7 EGO59087.1 - 0.11 11.5 0.1 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) RWD PF05773.17 EGO59087.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain 2OG-FeII_Oxy_2 PF13532.1 EGO59089.1 - 8.7e-32 110.5 0.0 1.2e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 EGO59089.1 - 2.3e-09 37.0 3.6 3.9e-09 36.2 2.5 1.4 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.11 EGO59089.1 - 0.0001 21.6 0.0 0.00021 20.6 0.0 1.5 1 0 0 1 1 1 1 CUE domain 2OG-FeII_Oxy PF03171.15 EGO59089.1 - 0.1 12.9 0.0 0.28 11.4 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 EGO59090.1 - 3.6e-26 90.0 14.9 1.3e-08 34.3 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Hamartin PF04388.7 EGO59093.1 - 2e-39 135.8 7.3 2e-39 135.8 5.0 1.9 1 1 0 2 2 2 1 Hamartin protein DUF4200 PF13863.1 EGO59093.1 - 0.43 10.5 38.4 0.035 14.0 3.9 3.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.6 EGO59093.1 - 1.7 9.0 15.5 3.2 8.2 3.7 3.3 2 2 1 3 3 3 0 Syntaxin 6, N-terminal DUF4066 PF13278.1 EGO59094.1 - 6.8e-27 93.7 0.2 1.3e-22 79.8 0.0 2.0 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 EGO59094.1 - 1e-05 25.0 0.0 2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Ribosomal_L23 PF00276.15 EGO59095.1 - 5e-13 48.8 0.0 8.8e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 Mito_carr PF00153.22 EGO59096.1 - 6.5e-62 205.2 0.5 9.5e-22 76.5 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.19 EGO59097.1 - 6.5e-45 153.5 19.4 8.1e-45 153.2 13.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO59097.1 - 1e-19 70.4 24.1 1.5e-19 69.9 16.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF383 PF04063.9 EGO59098.1 - 1.7e-67 226.7 0.0 3.4e-67 225.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EGO59098.1 - 1.2e-23 82.4 0.8 3.7e-23 80.8 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Adaptin_N PF01602.15 EGO59098.1 - 0.051 11.8 0.0 0.1 10.8 0.0 1.4 1 0 0 1 1 1 0 Adaptin N terminal region Bystin PF05291.6 EGO59099.1 - 2.9e-120 400.7 0.0 4.3e-120 400.2 0.0 1.1 1 0 0 1 1 1 1 Bystin CDC73 PF05179.9 EGO59100.1 - 3.2e-40 138.2 0.0 5.5e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family RGS PF00615.14 EGO59103.1 - 1.2e-35 122.1 1.0 8.2e-35 119.4 0.0 2.6 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 EGO59103.1 - 2e-25 88.2 0.2 3.9e-21 74.5 0.0 3.2 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Apc15p PF05841.6 EGO59103.1 - 4.4 8.0 8.4 19 6.0 5.8 2.1 1 0 0 1 1 1 0 Apc15p protein DUF3439 PF11921.3 EGO59104.1 - 0.17 11.6 9.8 1.6 8.5 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) ORC4_C PF14629.1 EGO59105.1 - 6.5e-65 218.3 0.0 1.1e-64 217.6 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EGO59105.1 - 4.6e-14 52.8 1.4 5.5e-13 49.3 0.1 3.2 2 1 0 2 2 1 1 AAA ATPase domain PHD PF00628.24 EGO59105.1 - 1.3e-11 44.0 5.6 2.3e-11 43.2 3.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EGO59105.1 - 1.6e-11 43.2 2.0 3.4e-11 42.2 1.4 1.6 1 0 0 1 1 1 1 PHD-finger AAA PF00004.24 EGO59105.1 - 2.7e-07 30.8 0.0 7.4e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EGO59105.1 - 3e-07 30.2 0.0 6.5e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EGO59105.1 - 1.1e-06 28.8 0.0 2.9e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain C1_1 PF00130.17 EGO59105.1 - 9.7e-05 22.0 0.8 0.00024 20.7 0.6 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) KAP_NTPase PF07693.9 EGO59105.1 - 0.00014 20.9 0.0 0.00025 20.1 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_29 PF13555.1 EGO59105.1 - 0.0011 18.4 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EGO59105.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase SMC_N PF02463.14 EGO59105.1 - 0.0017 17.6 0.0 0.0035 16.6 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain NB-ARC PF00931.17 EGO59105.1 - 0.0019 17.1 0.2 0.0039 16.0 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain FtsK_SpoIIIE PF01580.13 EGO59105.1 - 0.0021 17.5 0.0 0.0051 16.3 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF815 PF05673.8 EGO59105.1 - 0.0037 16.2 0.0 0.0063 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_10 PF12846.2 EGO59105.1 - 0.0045 16.4 0.1 0.12 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain MobB PF03205.9 EGO59105.1 - 0.0055 16.4 0.0 0.02 14.5 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EGO59105.1 - 0.0073 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ORC2 PF04084.9 EGO59105.1 - 0.0082 15.0 0.6 0.051 12.4 0.0 2.0 2 0 0 2 2 2 1 Origin recognition complex subunit 2 AAA_17 PF13207.1 EGO59105.1 - 0.0097 16.7 0.1 0.042 14.6 0.0 2.2 2 0 0 2 2 1 1 AAA domain Miro PF08477.8 EGO59105.1 - 0.02 15.4 0.0 0.058 13.9 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 EGO59105.1 - 0.022 15.0 0.0 0.064 13.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.12 EGO59105.1 - 0.03 13.8 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 EGO59105.1 - 0.031 14.1 0.1 0.11 12.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EGO59105.1 - 0.038 13.4 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 EGO59105.1 - 0.042 12.8 0.0 0.095 11.7 0.0 1.5 1 0 0 1 1 1 0 Septin zf-PHD-like PF15446.1 EGO59105.1 - 0.044 13.0 5.5 0.14 11.4 3.8 1.8 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 EGO59105.1 - 0.046 13.4 4.2 0.09 12.5 2.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FYVE_2 PF02318.11 EGO59105.1 - 0.051 13.4 2.2 0.11 12.3 1.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger ATP-synt_ab PF00006.20 EGO59105.1 - 0.051 13.0 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TrwB_AAD_bind PF10412.4 EGO59105.1 - 0.079 11.5 0.1 0.16 10.5 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PduV-EutP PF10662.4 EGO59105.1 - 0.088 12.2 0.0 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EGO59105.1 - 0.1 12.7 0.0 0.36 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 EGO59105.1 - 0.14 11.3 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein PHF5 PF03660.9 EGO59105.1 - 0.15 12.0 4.4 0.3 11.1 3.0 1.4 1 0 0 1 1 1 0 PHF5-like protein Bac_DnaA PF00308.13 EGO59105.1 - 0.16 11.5 0.0 12 5.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein zf-RING_2 PF13639.1 EGO59105.1 - 5.8 6.8 5.8 81 3.1 4.0 2.3 1 1 0 1 1 1 0 Ring finger domain DUF221 PF02714.10 EGO59106.1 - 2.3e-106 355.3 28.0 2.3e-106 355.3 19.4 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGO59106.1 - 4.3e-40 136.8 0.2 4.3e-40 136.8 0.1 3.5 2 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EGO59106.1 - 2.4e-18 65.8 0.0 6.4e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EGO59106.1 - 7e-07 29.6 9.2 0.041 14.4 5.2 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) FAD_binding_3 PF01494.14 EGO59107.1 - 5.3e-10 38.8 0.1 6.4e-09 35.3 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EGO59107.1 - 5.7e-06 25.3 0.0 9e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 EGO59107.1 - 0.0058 16.6 0.0 0.019 14.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain CYSTM PF12734.2 EGO59108.1 - 2.6e-08 33.8 7.4 2.6e-08 33.8 5.1 2.5 1 1 2 3 3 3 1 Cysteine-rich TM module stress tolerance Dispanin PF04505.7 EGO59108.1 - 0.0078 15.7 0.6 0.012 15.1 0.4 1.3 1 0 0 1 1 1 1 Interferon-induced transmembrane protein Pro-rich PF15240.1 EGO59108.1 - 0.73 9.9 8.7 0.88 9.6 6.0 1.0 1 0 0 1 1 1 0 Proline-rich RibD_C PF01872.12 EGO59109.1 - 5.2e-31 107.8 0.0 7e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain Sec1 PF00995.18 EGO59110.1 - 6.5e-135 450.9 0.0 7.4e-135 450.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family GrpE PF01025.14 EGO59110.1 - 0.11 12.0 1.5 0.26 10.8 1.1 1.6 1 0 0 1 1 1 0 GrpE Transp_cyt_pur PF02133.10 EGO59111.1 - 3.8e-21 75.1 35.4 5.9e-20 71.2 24.6 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NMT PF01233.14 EGO59111.1 - 0.0038 16.8 0.1 0.28 10.7 0.0 2.3 1 1 1 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain DNA_mis_repair PF01119.14 EGO59112.1 - 2e-34 117.6 0.1 1.9e-33 114.4 0.0 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EGO59112.1 - 1.4e-12 47.4 0.0 2.8e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGO59112.1 - 1.7e-11 43.7 0.0 4e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1768 PF08719.6 EGO59112.1 - 0.062 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) Menin PF05053.8 EGO59114.1 - 0.00038 18.7 4.0 0.00046 18.4 2.8 1.2 1 0 0 1 1 1 1 Menin DUF2457 PF10446.4 EGO59114.1 - 0.0013 17.5 6.1 0.0015 17.3 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop25 PF09805.4 EGO59114.1 - 0.044 13.8 2.9 0.059 13.4 2.0 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Neur_chan_memb PF02932.11 EGO59114.1 - 0.1 12.4 3.1 0.13 12.1 2.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pex14_N PF04695.8 EGO59114.1 - 0.23 11.5 9.4 0.33 11.0 6.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RP-C_C PF11800.3 EGO59114.1 - 0.26 10.9 6.1 0.41 10.3 4.2 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Pox_Ag35 PF03286.9 EGO59114.1 - 0.62 9.5 7.9 0.77 9.2 5.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tetraspannin PF00335.15 EGO59114.1 - 0.91 8.7 5.1 1.1 8.4 3.5 1.2 1 0 0 1 1 1 0 Tetraspanin family GRP PF07172.6 EGO59114.1 - 0.95 9.9 9.7 1.5 9.3 6.7 1.3 1 0 0 1 1 1 0 Glycine rich protein family DUF605 PF04652.11 EGO59114.1 - 0.96 8.7 7.5 1.3 8.3 5.2 1.2 1 0 0 1 1 1 0 Vta1 like GCD14 PF08704.5 EGO59114.1 - 3.2 7.1 5.4 4.2 6.8 3.8 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF2076 PF09849.4 EGO59114.1 - 4.6 7.2 16.2 5.8 6.8 11.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Zip PF02535.17 EGO59114.1 - 5.3 5.9 6.2 6.6 5.6 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter POX PF07526.6 EGO59114.1 - 7.8 6.7 5.9 12 6.1 4.1 1.4 1 0 0 1 1 1 0 Associated with HOX Zn_clus PF00172.13 EGO59115.1 - 2.6e-06 27.2 12.3 3.9e-06 26.6 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lon_C PF05362.8 EGO59117.1 - 9.3e-68 227.5 0.2 1.8e-67 226.6 0.2 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EGO59117.1 - 4.6e-27 95.0 0.0 9e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EGO59117.1 - 9.1e-24 84.1 0.0 2.9e-22 79.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGO59117.1 - 3.5e-09 36.4 0.0 8.5e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EGO59117.1 - 7.9e-08 31.8 0.0 1.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EGO59117.1 - 1.5e-06 28.3 0.2 7.5e-06 26.0 0.0 2.3 3 0 0 3 3 2 1 AAA ATPase domain AAA_17 PF13207.1 EGO59117.1 - 1.5e-05 25.7 0.0 6.4e-05 23.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EGO59117.1 - 9.2e-05 22.0 0.0 0.00023 20.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EGO59117.1 - 0.00014 21.3 0.0 0.0003 20.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EGO59117.1 - 0.00016 21.6 0.0 0.00042 20.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EGO59117.1 - 0.00039 19.5 0.1 0.0014 17.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGO59117.1 - 0.00047 20.3 0.0 0.0038 17.3 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EGO59117.1 - 0.0013 18.5 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO59117.1 - 0.0015 18.2 0.1 0.0082 15.8 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 EGO59117.1 - 0.0021 16.8 0.1 0.0048 15.6 0.1 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 EGO59117.1 - 0.0021 17.9 0.0 0.0046 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EGO59117.1 - 0.006 16.9 2.1 0.3 11.3 0.0 2.9 1 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGO59117.1 - 0.014 15.5 0.0 0.1 12.8 0.0 2.4 3 0 0 3 3 2 0 RNA helicase Zeta_toxin PF06414.7 EGO59117.1 - 0.017 14.1 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EGO59117.1 - 0.024 14.9 0.0 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGO59117.1 - 0.028 13.8 0.0 0.08 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EGO59117.1 - 0.028 14.0 0.0 0.085 12.5 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EGO59117.1 - 0.032 13.8 0.0 0.07 12.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_PrkA PF08298.6 EGO59117.1 - 0.044 12.4 0.1 1.4 7.5 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain AAA_24 PF13479.1 EGO59117.1 - 0.044 13.3 0.1 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EGO59117.1 - 0.06 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EGO59117.1 - 0.064 12.4 0.1 0.15 11.2 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 EGO59117.1 - 0.09 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 EGO59117.1 - 0.16 10.8 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.10 EGO59117.1 - 0.29 9.7 0.0 0.44 9.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Metallophos PF00149.23 EGO59119.1 - 7.3e-37 126.7 0.7 4.9e-30 104.4 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Ribonucleas_3_3 PF14622.1 EGO59120.1 - 1.8e-07 31.1 0.0 0.0034 17.3 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EGO59120.1 - 9.3e-07 29.2 0.0 2.9e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 EGO59120.1 - 3.4e-05 24.3 0.0 6.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif UCR_TM PF02921.9 EGO59120.1 - 0.11 12.8 0.2 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region PLA2_B PF01735.13 EGO59121.1 - 2.1e-24 85.5 0.0 4.6e-24 84.4 0.0 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Septin PF00735.13 EGO59122.1 - 9.7e-122 405.3 0.2 9.7e-122 405.3 0.1 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EGO59122.1 - 2.8e-07 30.5 0.0 6.7e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO59122.1 - 2.3e-05 23.9 0.6 0.00043 19.7 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EGO59122.1 - 5.5e-05 22.4 0.5 0.00047 19.3 0.3 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EGO59122.1 - 0.00021 20.8 0.7 0.0016 17.9 0.1 2.2 2 1 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 EGO59122.1 - 0.00023 21.4 3.0 0.019 15.2 0.0 2.6 2 1 0 2 2 2 1 ABC transporter AIG1 PF04548.11 EGO59122.1 - 0.00055 19.1 1.9 0.0013 17.9 0.0 2.2 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.1 EGO59122.1 - 0.0012 18.8 0.2 0.011 15.7 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain Miro PF08477.8 EGO59122.1 - 0.0028 18.1 0.5 0.011 16.2 0.0 2.3 2 1 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EGO59122.1 - 0.003 17.7 0.0 0.019 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Ras PF00071.17 EGO59122.1 - 0.0037 16.6 0.9 0.025 13.9 0.0 2.6 3 0 0 3 3 3 1 Ras family AAA_29 PF13555.1 EGO59122.1 - 0.0064 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EGO59122.1 - 0.012 15.0 1.8 0.019 14.4 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_25 PF13481.1 EGO59122.1 - 0.017 14.5 0.0 0.062 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EGO59122.1 - 0.022 14.6 8.1 0.46 10.2 0.0 3.6 3 1 0 3 3 3 0 Dynamin family Exonuc_VII_L PF02601.10 EGO59122.1 - 0.056 12.6 4.8 0.098 11.8 3.3 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sigma54_activat PF00158.21 EGO59122.1 - 0.059 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EGO59122.1 - 0.068 13.3 0.6 0.41 10.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_32 PF13654.1 EGO59122.1 - 0.072 11.7 10.2 0.36 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EGO59122.1 - 0.073 12.6 1.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EGO59122.1 - 0.074 12.7 2.4 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EGO59122.1 - 0.11 11.9 2.6 5 6.5 0.0 3.1 3 2 0 3 3 3 0 Conserved hypothetical ATP binding protein Strep_SA_rep PF06696.6 EGO59122.1 - 0.18 11.6 3.3 0.21 11.3 1.0 2.0 1 1 1 2 2 2 0 Streptococcal surface antigen repeat YlqD PF11068.3 EGO59122.1 - 0.32 11.0 10.4 0.61 10.1 7.2 1.4 1 0 0 1 1 1 0 YlqD protein IncA PF04156.9 EGO59122.1 - 0.68 9.4 8.4 1.1 8.8 5.8 1.3 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EGO59122.1 - 1.2 6.9 8.3 1.9 6.2 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF87 PF01935.12 EGO59122.1 - 4.4 7.0 7.6 2.6 7.8 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 S4 PF01479.20 EGO59123.1 - 3.7e-08 32.6 0.3 2.4e-07 30.0 0.2 2.4 1 1 0 1 1 1 1 S4 domain DUF3591 PF12157.3 EGO59123.1 - 0.014 13.8 6.2 0.014 13.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3591) La PF05383.12 EGO59124.1 - 2.4e-16 59.2 0.0 4e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 EGO59124.1 - 4.8e-09 36.0 0.1 9.9e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO59124.1 - 9.7e-09 34.7 1.0 9.7e-09 34.7 0.7 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO59124.1 - 0.00019 21.1 0.1 0.00042 20.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 EGO59125.1 - 8.9e-47 159.1 0.0 1.8e-46 158.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO59125.1 - 2.1e-08 33.9 6.3 4.6e-08 32.8 4.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HIT PF01230.18 EGO59126.1 - 2.2e-20 73.0 0.2 3.5e-20 72.3 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGO59126.1 - 0.0004 20.5 0.1 0.00061 19.9 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding MFS_1 PF07690.11 EGO59127.1 - 3.9e-29 101.4 30.3 4.7e-22 78.1 11.7 2.5 2 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO59127.1 - 1.2e-07 30.6 5.5 1.2e-07 30.6 3.8 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter DUF1751 PF08551.5 EGO59127.1 - 0.0026 18.0 0.3 0.014 15.7 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Ferrochelatase PF00762.14 EGO59128.1 - 4e-95 318.4 0.0 4.7e-95 318.1 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.11 EGO59129.1 - 5e-43 146.8 0.0 9.9e-43 145.8 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EGO59129.1 - 1.9e-36 125.5 0.0 2.8e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EGO59129.1 - 2.9e-15 56.5 1.5 9.1e-15 54.9 1.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EGO59129.1 - 6.6e-12 44.6 0.3 1.7e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 SAP domain VWA_2 PF13519.1 EGO59129.1 - 0.0016 18.5 0.1 0.0037 17.3 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EGO59129.1 - 0.011 15.4 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain HeH PF12949.2 EGO59129.1 - 0.048 13.2 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 HeH/LEM domain Sigma54_AID PF00309.15 EGO59129.1 - 1.6 8.2 6.4 11 5.5 0.2 3.0 3 0 0 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) Zn_clus PF00172.13 EGO59130.1 - 1e-06 28.5 11.6 2.2e-06 27.4 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_N PF00134.18 EGO59132.1 - 0.0011 18.5 0.1 0.0029 17.1 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain CPSase_L_D2 PF02786.12 EGO59133.1 - 7.8e-115 381.4 0.4 4.4e-85 284.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 EGO59133.1 - 1.2e-44 152.1 0.0 2.2e-44 151.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EGO59133.1 - 1.6e-44 150.5 0.0 4.2e-44 149.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 EGO59133.1 - 6.7e-44 148.9 0.1 1.3e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 EGO59133.1 - 4.7e-42 142.5 0.0 2.8e-20 72.4 0.0 3.0 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 EGO59133.1 - 1.3e-39 134.7 0.0 2.8e-39 133.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EGO59133.1 - 3.2e-39 134.5 0.2 1.1e-24 87.2 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 EGO59133.1 - 1.3e-32 112.8 0.0 3.7e-32 111.3 0.0 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 EGO59133.1 - 7.4e-25 87.3 0.1 3.3e-13 49.1 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EGO59133.1 - 2e-23 82.0 0.0 6.7e-22 77.2 0.0 3.1 3 0 0 3 3 3 1 MGS-like domain ATP-grasp PF02222.17 EGO59133.1 - 2.7e-18 65.9 0.2 6.6e-09 35.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGO59133.1 - 5.3e-16 58.6 1.0 6.5e-08 32.1 0.1 2.8 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EGO59133.1 - 4.2e-07 29.9 1.7 0.019 14.8 0.0 3.3 4 0 0 4 4 3 2 ATP-grasp domain Peptidase_C26 PF07722.8 EGO59133.1 - 5e-06 26.1 0.3 0.00028 20.4 0.2 2.6 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.14 EGO59133.1 - 0.00018 21.1 0.2 0.61 9.6 0.0 3.4 3 1 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.19 EGO59133.1 - 0.00038 19.9 0.0 0.00094 18.6 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family Ion_trans PF00520.26 EGO59135.1 - 3.5e-06 26.4 23.2 0.0002 20.6 16.1 2.3 1 1 0 1 1 1 1 Ion transport protein SE PF08491.5 EGO59138.1 - 1.5e-87 292.9 0.0 2e-87 292.5 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EGO59138.1 - 2.6e-10 39.8 0.7 5.5e-06 25.6 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGO59138.1 - 7e-10 38.3 0.7 2.7e-08 33.1 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EGO59138.1 - 6.7e-08 31.7 0.7 6.6e-07 28.5 0.5 2.0 1 1 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EGO59138.1 - 5.3e-06 25.6 0.0 1.3e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EGO59138.1 - 9.3e-06 24.9 0.4 1.5e-05 24.3 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO59138.1 - 1e-05 24.5 0.6 2e-05 23.6 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGO59138.1 - 1.5e-05 24.9 0.3 4.6e-05 23.3 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO59138.1 - 0.00038 20.3 0.2 0.00072 19.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO59138.1 - 0.00088 19.6 0.3 0.0021 18.4 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGO59138.1 - 0.0011 17.9 0.3 0.25 10.2 0.1 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Shikimate_DH PF01488.15 EGO59138.1 - 0.0022 18.0 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EGO59138.1 - 0.0059 16.0 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EGO59138.1 - 0.0071 16.0 0.1 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EGO59138.1 - 0.011 14.3 0.2 3.7 6.0 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 EGO59138.1 - 0.016 13.7 0.1 0.023 13.2 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.16 EGO59138.1 - 0.032 14.0 0.5 0.082 12.7 0.3 1.7 1 0 0 1 1 1 0 ThiF family NAD_Gly3P_dh_N PF01210.18 EGO59138.1 - 0.036 13.8 0.1 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TPR_14 PF13428.1 EGO59139.1 - 0.00037 20.8 3.0 2.7 8.8 0.1 6.2 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO59139.1 - 0.0019 17.8 1.0 12 5.9 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO59139.1 - 0.43 11.3 12.0 2.4 8.9 0.0 6.2 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGO59139.1 - 0.48 10.7 13.2 0.69 10.2 0.3 5.5 6 1 0 6 6 6 0 Tetratricopeptide repeat Mito_carr PF00153.22 EGO59140.1 - 2.6e-63 209.7 2.6 1.4e-19 69.5 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S26 PF10502.4 EGO59141.1 - 0.00018 21.0 0.1 0.0043 16.5 0.0 2.1 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 EGO59141.1 - 0.096 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase S24-like EIF_2_alpha PF07541.7 EGO59142.1 - 2.9e-39 133.3 0.0 6.5e-39 132.1 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EGO59142.1 - 3e-13 49.6 0.7 5.2e-13 48.8 0.5 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Hemagglutinin PF00509.13 EGO59142.1 - 0.038 12.1 0.1 0.064 11.4 0.1 1.3 1 0 0 1 1 1 0 Haemagglutinin cNMP_binding PF00027.24 EGO59143.1 - 3.6e-38 129.2 0.0 4.7e-18 64.7 0.0 5.0 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EGO59143.1 - 6.8e-15 55.5 8.6 2.6e-14 53.6 4.0 2.8 2 1 0 2 2 2 1 Patatin-like phospholipase DUF1056 PF06341.6 EGO59143.1 - 3.6 7.6 6.8 8.5 6.4 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) Pyridoxal_deC PF00282.14 EGO59144.1 - 1.3e-102 343.0 0.0 1.6e-102 342.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Anoctamin PF04547.7 EGO59146.1 - 6.2e-125 417.3 9.2 7.9e-125 417.0 6.4 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel FMN_dh PF01070.13 EGO59147.1 - 6.4e-120 400.2 0.3 8.3e-120 399.8 0.2 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EGO59147.1 - 1.4e-23 82.4 0.0 2.7e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EGO59147.1 - 1.5e-07 30.7 0.1 2.4e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EGO59147.1 - 0.00041 19.3 0.5 0.0015 17.5 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EGO59147.1 - 0.00052 19.2 0.2 0.00091 18.4 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EGO59147.1 - 0.0018 17.6 0.8 0.2 10.8 0.0 2.4 1 1 0 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.9 EGO59147.1 - 0.029 13.4 0.1 3.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.7 EGO59147.1 - 0.093 11.6 0.0 1.8 7.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF561) Ras PF00071.17 EGO59148.1 - 3.7e-40 136.9 0.0 6.6e-38 129.6 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EGO59148.1 - 6.4e-19 68.6 0.0 8.5e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO59148.1 - 1.5e-10 40.6 0.0 2.3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGO59148.1 - 0.0028 17.5 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGO59148.1 - 0.004 16.3 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGO59148.1 - 0.0051 15.9 0.0 0.0067 15.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.1 EGO59148.1 - 0.057 12.9 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EGO59148.1 - 0.098 12.1 0.1 1.4 8.4 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EGO59148.1 - 0.14 12.1 0.1 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EGO59148.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 EGO59148.1 - 0.41 10.6 1.9 0.35 10.7 0.3 1.9 2 1 0 2 2 2 0 AAA domain Ribonuclease_3 PF00636.21 EGO59149.1 - 6.9e-43 145.7 0.1 1.9e-20 73.4 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EGO59149.1 - 1.5e-24 86.3 0.0 3.2e-10 40.0 0.0 3.9 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 EGO59149.1 - 3.4e-24 84.4 0.1 2.7e-22 78.3 0.0 2.9 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 EGO59149.1 - 2e-16 59.6 0.1 4.4e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO59149.1 - 2.4e-13 50.3 0.0 4.6e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGO59149.1 - 7.9e-11 41.7 0.0 2.2e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGO59149.1 - 0.0095 16.0 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain SNF2_N PF00176.18 EGO59149.1 - 0.017 13.8 0.2 0.072 11.8 0.1 1.9 1 1 0 1 1 1 0 SNF2 family N-terminal domain Fructosamin_kin PF03881.9 EGO59149.1 - 0.053 12.4 0.0 0.094 11.6 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase PNPOx_C PF10590.4 EGO59150.1 - 2.9e-21 74.6 3.1 1.9e-20 72.0 2.6 2.1 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EGO59150.1 - 4.4e-12 45.8 0.0 2.6e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EGO59150.1 - 0.065 13.5 0.0 0.16 12.2 0.0 1.7 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Sec63 PF02889.11 EGO59151.1 - 2.3e-149 496.8 0.0 3.4e-95 318.8 0.1 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EGO59151.1 - 2.2e-52 176.9 0.1 7.8e-28 97.0 0.2 3.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO59151.1 - 3.6e-17 61.9 0.0 6.2e-07 29.1 0.0 3.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EGO59151.1 - 1.6e-14 54.1 0.1 8.4e-06 25.7 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EGO59151.1 - 7e-08 32.6 0.0 0.034 14.2 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EGO59151.1 - 8.6e-07 28.6 0.8 0.027 14.2 0.0 3.3 3 0 0 3 3 3 2 Part of AAA domain AAA PF00004.24 EGO59151.1 - 0.0025 18.0 1.3 2.2 8.4 0.0 4.6 5 1 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EGO59151.1 - 0.014 14.7 0.0 19 4.6 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein TraD_N PF12615.3 EGO59151.1 - 0.036 14.3 0.0 0.16 12.3 0.0 2.1 1 0 0 1 1 1 0 F sex factor protein N terminal Ras PF00071.17 EGO59152.1 - 5.2e-65 217.7 0.0 8.2e-65 217.1 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGO59152.1 - 1.4e-19 70.7 0.0 2e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO59152.1 - 2.2e-13 49.8 0.0 2.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGO59152.1 - 2.8e-06 26.8 0.0 5.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGO59152.1 - 7.4e-06 25.2 0.0 8.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGO59152.1 - 0.0018 18.2 0.0 0.0088 15.9 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGO59152.1 - 0.014 14.6 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EGO59152.1 - 0.071 12.3 0.0 0.35 10.1 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 EGO59152.1 - 0.079 12.5 0.0 0.28 10.7 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EGO59152.1 - 0.11 11.7 0.0 0.31 10.2 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGO59152.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 EGO59152.1 - 0.18 10.4 0.5 13 4.3 0.0 2.8 1 1 1 2 2 2 0 G-protein alpha subunit NCA2 PF08637.5 EGO59153.1 - 4.2e-95 317.9 0.0 8.9e-95 316.8 0.0 1.6 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.8 EGO59154.1 - 6.5e-15 55.5 15.2 6.5e-15 55.5 10.6 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Amidohydro_1 PF01979.15 EGO59155.1 - 8.9e-32 111.0 1.0 1.2e-31 110.6 0.7 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGO59155.1 - 2.5e-14 53.9 0.9 4.4e-12 46.6 0.6 2.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGO59155.1 - 1.8e-10 40.6 9.6 1.2e-09 37.8 1.7 2.3 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EGO59155.1 - 3.2e-05 23.6 0.3 0.00015 21.4 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase DUF3775 PF12616.3 EGO59155.1 - 0.099 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) bZIP_1 PF00170.16 EGO59156.1 - 9.1e-08 31.9 10.1 2.6e-06 27.2 7.0 2.2 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGO59156.1 - 0.029 14.1 10.1 15 5.5 7.0 2.8 1 1 0 1 1 1 0 Basic region leucine zipper Adeno_PIX PF03955.9 EGO59156.1 - 0.032 14.7 2.1 0.052 14.0 0.0 2.2 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF3298 PF11738.3 EGO59156.1 - 0.92 10.0 3.6 21 5.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3298) Profilin PF00235.14 EGO59158.1 - 6.7e-37 126.2 0.2 7.5e-37 126.1 0.2 1.0 1 0 0 1 1 1 1 Profilin YL1_C PF08265.6 EGO59159.1 - 7.8e-16 57.3 0.1 1.2e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DASH_Dad4 PF08650.5 EGO59160.1 - 1.5e-28 98.5 7.4 1.6e-28 98.4 5.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 Biotin_carb_C PF02785.14 EGO59160.1 - 0.067 13.1 0.1 0.077 12.9 0.0 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain GM_CSF PF01109.12 EGO59160.1 - 0.14 12.1 0.6 0.16 11.9 0.4 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor DASH_Dad1 PF08649.5 EGO59160.1 - 0.19 11.4 3.2 0.25 11.0 2.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 Actin PF00022.14 EGO59161.1 - 3.2e-56 190.4 0.0 5.2e-32 110.7 0.0 2.4 2 1 0 2 2 2 2 Actin IR1-M PF12185.3 EGO59161.1 - 0.65 9.7 5.2 0.16 11.7 0.8 2.1 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain AAA PF00004.24 EGO59162.1 - 7.1e-51 171.8 0.0 4.2e-39 133.7 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGO59162.1 - 1.2e-07 31.3 3.3 0.068 12.5 0.1 3.8 2 2 1 3 3 3 3 AAA domain AAA_16 PF13191.1 EGO59162.1 - 2.3e-07 31.0 0.6 0.011 15.7 0.2 3.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.1 EGO59162.1 - 1e-05 25.5 0.0 0.0013 18.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGO59162.1 - 0.00071 19.7 4.4 3.7 7.6 1.3 4.6 3 2 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EGO59162.1 - 0.0017 18.1 0.8 1.4 8.6 0.1 3.4 3 1 0 3 3 2 1 Part of AAA domain KaiC PF06745.8 EGO59162.1 - 0.0021 17.2 0.8 0.023 13.8 0.1 2.6 3 0 0 3 3 3 1 KaiC AAA_2 PF07724.9 EGO59162.1 - 0.0022 17.9 0.0 0.058 13.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EGO59162.1 - 0.0022 18.1 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 EGO59162.1 - 0.0024 17.5 1.4 0.24 11.0 0.6 3.3 3 1 0 3 3 3 1 NACHT domain AAA_14 PF13173.1 EGO59162.1 - 0.0027 17.6 0.0 3.6 7.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGO59162.1 - 0.003 17.2 0.2 0.26 10.9 0.0 3.2 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EGO59162.1 - 0.005 15.9 0.0 0.18 10.7 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus Bac_DnaA PF00308.13 EGO59162.1 - 0.005 16.5 1.8 0.74 9.4 0.0 3.2 2 1 0 2 2 2 1 Bacterial dnaA protein AFG1_ATPase PF03969.11 EGO59162.1 - 0.0091 14.8 0.0 0.1 11.3 0.0 2.2 2 0 0 2 2 2 1 AFG1-like ATPase ABC_tran PF00005.22 EGO59162.1 - 0.03 14.5 0.0 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 ABC transporter IstB_IS21 PF01695.12 EGO59162.1 - 0.037 13.4 0.0 3 7.2 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 EGO59162.1 - 0.041 14.7 0.2 7.8 7.3 0.1 3.1 2 2 0 2 2 2 0 AAA domain DAP3 PF10236.4 EGO59162.1 - 0.13 11.1 0.0 3.2 6.6 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Mg_chelatase PF01078.16 EGO59162.1 - 0.13 11.4 1.5 0.65 9.1 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PAS_3 PF08447.6 EGO59164.1 - 0.00015 21.7 0.0 0.097 12.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EGO59164.1 - 0.0019 18.5 0.0 0.0043 17.4 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EGO59164.1 - 0.04 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 PAS fold CENP-B_dimeris PF09026.5 EGO59164.1 - 0.18 12.0 13.1 0.35 11.1 9.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain IFT57 PF10498.4 EGO59164.1 - 0.53 8.9 3.5 0.87 8.2 2.4 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Nucleoplasmin PF03066.10 EGO59164.1 - 1.5 8.3 9.8 2.8 7.4 6.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 EGO59164.1 - 3.9 5.3 9.9 6.3 4.7 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EGO59164.1 - 7.8 5.6 8.3 12 5.0 5.7 1.2 1 0 0 1 1 1 0 NOA36 protein SMK-1 PF04802.10 EGO59165.1 - 1.6e-73 246.3 1.1 1.6e-73 246.3 0.7 2.6 2 1 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Chlam_vir PF05475.6 EGO59165.1 - 0.023 13.8 0.1 0.053 12.6 0.1 1.6 1 0 0 1 1 1 0 Chlamydia virulence protein PGP3-D Glycos_transf_2 PF00535.21 EGO59169.1 - 3.3e-22 78.9 0.0 1.1e-21 77.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGO59169.1 - 6.9e-09 35.8 0.8 5.1e-05 23.1 0.0 2.9 3 0 0 3 3 3 2 Glycosyltransferase like family 2 PepSY_TM_2 PF13703.1 EGO59170.1 - 0.87 9.8 12.3 0.66 10.1 0.2 4.0 3 1 1 4 4 4 0 PepSY-associated TM helix DPM3 PF08285.6 EGO59170.1 - 1.8 8.4 10.8 0.33 10.8 0.4 3.3 2 2 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Sugar_tr PF00083.19 EGO59171.1 - 3.2e-88 296.2 18.8 3.9e-88 296.0 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO59171.1 - 4.4e-32 111.1 43.3 2.3e-26 92.3 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.6 EGO59171.1 - 4.6 6.4 5.4 0.96 8.7 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) UPF0075 PF03702.9 EGO59172.1 - 2.5e-82 276.6 0.0 3e-82 276.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) Fungal_trans PF04082.13 EGO59173.1 - 2.2e-08 33.3 0.1 3.3e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO59173.1 - 2.3e-07 30.5 6.5 2.3e-07 30.5 4.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.22 EGO59174.1 - 3.7e-47 160.0 0.2 2.4e-28 99.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 EGO59174.1 - 1.9e-36 125.9 23.9 9.7e-23 80.9 4.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EGO59174.1 - 1.4e-08 35.0 0.0 0.47 10.3 0.0 4.4 2 2 1 3 3 3 2 AAA domain AAA_25 PF13481.1 EGO59174.1 - 2.2e-08 33.7 0.0 0.0016 17.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EGO59174.1 - 6e-08 32.1 7.3 0.0013 17.9 0.6 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGO59174.1 - 5.7e-05 22.5 2.4 0.026 14.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EGO59174.1 - 6e-05 22.2 0.1 0.15 11.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EGO59174.1 - 0.00012 21.6 0.0 0.017 14.6 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 EGO59174.1 - 0.00016 22.1 0.1 0.33 11.4 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 EGO59174.1 - 0.00033 21.0 8.4 0.0012 19.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EGO59174.1 - 0.00039 19.9 0.2 0.23 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain NACHT PF05729.7 EGO59174.1 - 0.00093 18.8 0.6 0.71 9.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EGO59174.1 - 0.004 16.8 0.5 2.1 8.1 0.0 3.4 3 0 0 3 3 3 1 Part of AAA domain MMR_HSR1 PF01926.18 EGO59174.1 - 0.0041 17.0 0.0 0.47 10.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 EGO59174.1 - 0.0044 16.8 0.1 2.7 7.9 0.0 3.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 EGO59174.1 - 0.0051 16.8 0.5 3.4 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 EGO59174.1 - 0.0059 15.5 0.1 0.76 8.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein ATP-synt_ab PF00006.20 EGO59174.1 - 0.0071 15.8 0.1 2.1 7.8 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 EGO59174.1 - 0.0077 17.0 1.3 0.46 11.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EGO59174.1 - 0.0088 15.8 0.2 0.0088 15.8 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 Pox_A32 PF04665.7 EGO59174.1 - 0.015 14.5 2.4 1.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Dynamin_N PF00350.18 EGO59174.1 - 0.018 14.8 3.1 1.6 8.5 0.1 3.0 3 0 0 3 3 3 0 Dynamin family MobB PF03205.9 EGO59174.1 - 0.021 14.5 2.1 0.39 10.4 0.1 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EGO59174.1 - 0.022 14.8 3.1 10 6.2 0.0 3.8 5 0 0 5 5 4 0 AAA domain Viral_helicase1 PF01443.13 EGO59174.1 - 0.033 13.7 0.0 11 5.4 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 EGO59174.1 - 0.051 13.0 1.9 5.9 6.2 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EGO59174.1 - 0.094 13.0 0.2 8 6.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EGO59174.1 - 0.1 12.2 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase DAP3 PF10236.4 EGO59174.1 - 0.13 11.2 0.6 7.4 5.4 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.4 EGO59174.1 - 0.14 11.1 0.1 2 7.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EGO59174.1 - 0.14 10.9 2.3 6.8 5.4 0.0 3.8 4 1 0 4 4 4 0 NB-ARC domain Zeta_toxin PF06414.7 EGO59174.1 - 0.18 10.8 0.3 2 7.4 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.1 EGO59174.1 - 0.19 11.2 0.9 8 5.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EGO59174.1 - 0.38 9.7 0.0 0.74 8.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC_ATPase PF09818.4 EGO59174.1 - 0.61 8.6 5.8 0.87 8.0 0.0 3.0 4 0 0 4 4 4 0 Predicted ATPase of the ABC class Glyco_hydro_17 PF00332.13 EGO59175.1 - 0.00016 20.8 0.2 0.00032 19.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Zip PF02535.17 EGO59176.1 - 8.2e-61 205.7 8.5 5.2e-60 203.1 5.9 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter Bul1_C PF04426.7 EGO59177.1 - 0.00058 19.1 0.2 0.0014 17.8 0.1 1.6 2 0 0 2 2 2 1 Bul1 C terminus Arrestin_N PF00339.24 EGO59177.1 - 0.036 13.8 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Metallophos PF00149.23 EGO59178.1 - 5.9e-08 32.3 4.7 1.6e-07 30.9 3.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGO59178.1 - 3.2e-06 27.0 0.0 5.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain EMP70 PF02990.11 EGO59179.1 - 1.3e-165 551.8 0.6 2.4e-165 550.9 0.4 1.4 1 1 0 1 1 1 1 Endomembrane protein 70 DUF3267 PF11667.3 EGO59179.1 - 6.5 7.0 18.1 0.16 12.2 1.5 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3267) LRV_FeS PF05484.6 EGO59181.1 - 0.067 12.7 1.0 0.094 12.3 0.7 1.2 1 0 0 1 1 1 0 LRV protein FeS4 cluster Peptidase_C12 PF01088.16 EGO59182.1 - 2.5e-63 213.1 0.0 2.8e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SUV3_C PF12513.3 EGO59183.1 - 2.1e-17 62.3 1.2 3.8e-17 61.4 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EGO59183.1 - 8.6e-09 35.1 0.0 2e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TK PF00265.13 EGO59183.1 - 0.091 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase Synaptobrevin PF00957.16 EGO59184.1 - 1.4e-31 107.9 0.5 1.8e-31 107.5 0.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EGO59184.1 - 9e-23 79.6 0.0 1.4e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SpoIIAA-like PF11964.3 EGO59184.1 - 0.027 14.7 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 SpoIIAA-like adh_short PF00106.20 EGO59185.1 - 6.7e-12 45.6 0.0 1.6e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO59185.1 - 5.6e-07 29.3 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO59185.1 - 0.0042 16.5 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO59185.1 - 0.044 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EGO59185.1 - 0.068 12.9 0.3 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RNase_H2-Ydr279 PF09468.5 EGO59185.1 - 0.65 9.1 7.2 0.92 8.6 5.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) UvrD-helicase PF00580.16 EGO59185.1 - 0.72 9.0 5.6 1.3 8.2 3.9 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain G-patch PF01585.18 EGO59186.1 - 1.4e-07 31.1 0.3 2.6e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 G-patch domain Yip1 PF04893.12 EGO59187.1 - 2.3e-14 53.2 10.3 3.5e-14 52.6 7.1 1.4 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EGO59187.1 - 0.007 16.0 6.9 0.012 15.3 4.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) 7TM_transglut PF14402.1 EGO59187.1 - 0.079 11.8 7.6 0.12 11.3 5.3 1.2 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase Na_Ca_ex PF01699.19 EGO59188.1 - 1.8e-25 89.1 17.6 8.6e-15 54.5 3.5 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.7 EGO59188.1 - 0.13 12.1 1.6 11 5.9 0.0 2.8 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) ODV-E18 PF10717.4 EGO59188.1 - 0.18 11.2 2.0 8.2 5.9 0.1 3.2 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 SirB PF04247.7 EGO59188.1 - 0.63 9.7 10.4 2.3 7.9 0.0 4.3 5 0 0 5 5 5 0 Invasion gene expression up-regulator, SirB Abhydrolase_9_N PF15420.1 EGO59188.1 - 0.68 9.6 6.5 4.9 6.8 0.0 3.1 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus DUF2721 PF11026.3 EGO59188.1 - 1.2 8.8 7.1 0.82 9.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DEAD PF00270.24 EGO59189.1 - 3.4e-24 85.2 0.0 6.5e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 EGO59189.1 - 1.7e-13 50.9 0.2 5.2e-13 49.3 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 EGO59189.1 - 8.1e-11 41.6 0.1 2.6e-10 39.9 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.6 EGO59189.1 - 0.00031 20.7 0.0 0.00067 19.6 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like Lipase_GDSL PF00657.17 EGO59190.1 - 2.9e-12 46.9 0.1 4.5e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RabGAP-TBC PF00566.13 EGO59192.1 - 6.7e-49 166.2 0.5 7.2e-47 159.6 0.0 3.1 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF1664 PF07889.7 EGO59192.1 - 0.084 12.6 8.2 0.12 12.1 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.6 EGO59192.1 - 0.22 9.0 6.2 0.021 12.3 0.8 1.7 2 0 0 2 2 2 0 Prominin IncA PF04156.9 EGO59192.1 - 1.5 8.4 37.4 0.023 14.2 2.1 4.0 4 0 0 4 4 4 0 IncA protein Reticulon PF02453.12 EGO59193.1 - 1.2e-39 135.6 4.1 1.8e-39 135.0 2.8 1.4 1 0 0 1 1 1 1 Reticulon DUF1548 PF07579.6 EGO59193.1 - 0.0078 16.3 0.1 0.093 12.8 0.1 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1548) PAP2 PF01569.16 EGO59193.1 - 0.042 13.5 1.5 0.067 12.8 0.6 1.7 1 1 0 1 1 1 0 PAP2 superfamily Ribosomal_L30_N PF08079.7 EGO59193.1 - 0.1 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Aminotran_1_2 PF00155.16 EGO59194.1 - 1.2e-66 225.1 0.0 1.4e-66 224.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGO59194.1 - 0.047 11.9 0.0 0.095 10.9 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 EGO59194.1 - 0.16 10.5 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Allinase Sugar_tr PF00083.19 EGO59196.1 - 6.1e-118 394.2 33.5 7.1e-118 394.0 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO59196.1 - 7.4e-20 70.9 39.2 2.3e-17 62.7 20.8 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily PUCC PF03209.10 EGO59196.1 - 0.00094 18.0 7.0 0.00094 18.0 4.8 1.8 2 0 0 2 2 2 1 PUCC protein DUF2530 PF10745.4 EGO59196.1 - 1.8 8.6 13.8 0.041 13.8 1.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) Xpo1 PF08389.7 EGO59197.1 - 8.5e-28 97.1 0.9 6.2e-27 94.3 0.2 2.8 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 EGO59197.1 - 6.5e-10 38.7 2.3 2.8e-08 33.5 0.2 3.7 2 1 1 3 3 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 EGO59197.1 - 0.0054 15.1 3.0 0.22 9.8 0.1 3.0 2 2 1 3 3 3 2 Adaptin N terminal region 5-FTHF_cyc-lig PF01812.15 EGO59198.1 - 7.8e-22 77.9 0.0 1e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family OPT PF03169.10 EGO59199.1 - 1.1e-219 731.0 37.8 1.3e-219 730.8 26.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein His_Phos_2 PF00328.17 EGO59200.1 - 1.5e-51 175.8 0.0 1.7e-51 175.6 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) JmjC PF02373.17 EGO59201.1 - 0.033 14.4 1.2 0.039 14.2 0.8 1.1 1 0 0 1 1 1 0 JmjC domain, hydroxylase OppC_N PF12911.2 EGO59202.1 - 0.97 8.8 3.1 2.4 7.6 2.2 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C RCR PF12273.3 EGO59202.1 - 2 8.9 6.5 13 6.3 4.5 2.2 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Inositol_P PF00459.20 EGO59203.1 - 9.3e-63 212.0 0.0 1.1e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family End3 PF12761.2 EGO59204.1 - 1.4e-75 253.2 4.1 1.9e-75 252.7 2.8 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EGO59204.1 - 2.6e-50 168.4 0.0 7.3e-49 163.8 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EGO59204.1 - 5.7e-07 28.3 0.2 1.7e-06 26.8 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EGO59204.1 - 8.9e-07 28.4 0.1 8.3e-06 25.3 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 EGO59204.1 - 1.4e-05 25.1 0.0 0.00011 22.2 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EGO59204.1 - 0.00017 21.1 0.1 0.0026 17.5 0.2 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 EGO59204.1 - 0.0049 16.1 0.1 0.013 14.7 0.1 1.8 1 0 0 1 1 1 1 EF hand MDMPI_N PF11716.3 EGO59204.1 - 0.013 15.9 1.6 0.034 14.5 0.0 2.3 2 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain IncA PF04156.9 EGO59204.1 - 0.5 9.9 7.8 3.2 7.3 2.8 2.4 2 0 0 2 2 2 0 IncA protein COG2 PF06148.6 EGO59204.1 - 1.4 8.7 4.7 0.58 10.0 0.4 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF641 PF04859.7 EGO59204.1 - 3.2 7.5 6.6 0.41 10.4 1.1 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) SlyX PF04102.7 EGO59204.1 - 5.4 7.4 7.0 7.1 7.0 0.3 2.8 2 0 0 2 2 2 0 SlyX TBPIP PF07106.8 EGO59204.1 - 9.4 5.7 9.0 24 4.4 3.3 2.5 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ACBP PF00887.14 EGO59205.1 - 2.7e-26 91.0 2.0 3e-26 90.8 1.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Tyr-DNA_phospho PF06087.7 EGO59206.1 - 2.2e-131 438.5 0.0 2.7e-131 438.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Thioredoxin PF00085.15 EGO59207.1 - 6.2e-39 131.8 0.1 3.2e-23 81.3 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EGO59207.1 - 8.5e-09 35.4 0.0 0.0022 17.8 0.0 3.9 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EGO59207.1 - 4.7e-08 33.2 1.7 0.00048 20.2 0.1 4.7 3 2 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGO59207.1 - 6.7e-07 29.2 1.0 0.00073 19.5 0.1 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EGO59207.1 - 3.6e-06 26.9 0.4 0.082 13.0 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin-like HyaE PF07449.6 EGO59207.1 - 0.0046 16.8 0.0 1.7 8.5 0.0 3.2 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 EGO59207.1 - 0.023 14.4 4.0 0.029 14.2 0.0 3.2 3 0 0 3 3 3 0 Thioredoxin domain 7TM_GPCR_Srh PF10318.4 EGO59207.1 - 0.067 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Acetyltransf_10 PF13673.1 EGO59208.1 - 1.3e-08 34.9 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO59208.1 - 1.9e-08 34.2 0.1 3.5e-08 33.3 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGO59208.1 - 3.2e-08 33.1 0.0 6.1e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EGO59208.1 - 0.012 15.7 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGO59208.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PLDc_2 PF13091.1 EGO59209.1 - 1.5e-14 53.8 0.0 7.1e-06 25.7 0.0 3.6 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.17 EGO59209.1 - 1.7e-12 46.6 1.0 6.9e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif MFS_1 PF07690.11 EGO59210.1 - 9.1e-34 116.6 25.5 5.4e-27 94.4 1.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO59210.1 - 1.5e-08 33.6 6.5 1.5e-08 33.6 4.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 EGO59210.1 - 6 4.8 12.4 2.9 5.8 2.8 3.3 2 2 1 3 3 3 0 Transmembrane secretion effector DNA_topoisoIV PF00521.15 EGO59212.1 - 1.2e-121 406.6 0.0 1.9e-121 405.8 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EGO59212.1 - 4.8e-30 104.0 0.9 1.1e-29 102.8 0.6 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EGO59212.1 - 4.5e-12 45.8 0.0 1.6e-11 44.0 0.0 2.0 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EGO59212.1 - 4.4e-09 36.0 0.1 2.1e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DAGK_cat PF00781.19 EGO59213.1 - 9.9e-09 34.7 0.0 3.3e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ndc1_Nup PF09531.5 EGO59213.1 - 10 4.4 6.7 14 3.9 4.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TRM PF02005.11 EGO59214.1 - 1e-106 357.0 0.0 6.6e-94 314.9 0.0 2.1 1 1 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.9 EGO59214.1 - 0.0053 16.1 0.1 0.016 14.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGO59214.1 - 0.0063 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MFMR PF07777.6 EGO59214.1 - 0.067 13.1 4.1 0.17 11.8 2.9 1.6 1 0 0 1 1 1 0 G-box binding protein MFMR SseC PF04888.7 EGO59215.1 - 0.17 11.2 0.5 0.23 10.7 0.3 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family PBD PF00786.23 EGO59216.1 - 0.031 14.6 1.7 0.32 11.4 1.2 2.8 1 1 0 1 1 1 0 P21-Rho-binding domain Sec62 PF03839.11 EGO59217.1 - 8.1e-54 182.4 0.5 8.1e-54 182.4 0.3 2.0 2 0 0 2 2 2 1 Translocation protein Sec62 Abhydrolase_6 PF12697.2 EGO59218.1 - 1.5e-27 96.9 0.3 2.9e-27 96.0 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO59218.1 - 4e-14 52.7 0.0 4.7e-10 39.4 0.0 2.6 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO59218.1 - 3.3e-12 46.3 0.0 9.4e-10 38.4 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF915 PF06028.6 EGO59218.1 - 5.9e-06 25.5 0.0 1.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 EGO59218.1 - 5e-05 22.8 0.0 9.3e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 EGO59218.1 - 0.00086 18.8 0.0 0.81 9.0 0.0 2.7 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 EGO59218.1 - 0.0041 16.7 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 EGO59218.1 - 0.007 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EGO59218.1 - 0.038 13.2 0.0 1.4 8.1 0.0 2.6 2 1 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.15 EGO59218.1 - 0.054 13.7 0.2 0.17 12.0 0.1 2.0 1 1 0 1 1 1 0 Thioesterase domain DUF2305 PF10230.4 EGO59218.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Spo7 PF03907.8 EGO59219.1 - 4.5e-65 219.1 0.0 6.1e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein DSPc PF00782.15 EGO59220.1 - 6.5e-10 38.7 0.0 8.7e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EGO59220.1 - 0.0015 17.4 0.0 0.002 17.0 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase NOA36 PF06524.7 EGO59221.1 - 2.4 7.3 3.3 4.9 6.3 2.3 1.4 1 0 0 1 1 1 0 NOA36 protein DUF3594 PF12165.3 EGO59222.1 - 0.17 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3594) p450 PF00067.17 EGO59223.1 - 8.4e-67 225.6 0.0 1.1e-66 225.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pec_lyase_C PF00544.14 EGO59223.1 - 3.5e-25 88.6 4.7 1.1e-23 83.8 3.3 2.3 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EGO59223.1 - 0.2 11.4 8.5 0.56 9.9 5.9 1.7 1 1 0 1 1 1 0 Right handed beta helix region DUF1996 PF09362.5 EGO59224.1 - 1.3e-54 185.4 7.1 4.7e-54 183.5 1.8 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF1996) Zn_clus PF00172.13 EGO59225.1 - 0.0018 18.1 8.4 0.0035 17.2 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sld5 PF05916.6 EGO59227.1 - 8.1e-27 93.6 0.0 1.3e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein SR-25 PF10500.4 EGO59229.1 - 0.004 16.6 12.8 0.004 16.6 8.9 5.2 6 0 0 6 6 6 1 Nuclear RNA-splicing-associated protein VP_N-CPKC PF11475.3 EGO59230.1 - 0.17 11.4 0.3 5.6 6.6 0.0 2.7 2 0 0 2 2 2 0 Virion protein N terminal domain Glyco_hydro_76 PF03663.9 EGO59231.1 - 5.7e-142 473.4 0.2 8.2e-142 472.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EGO59231.1 - 0.022 13.7 2.4 0.33 9.9 0.1 2.5 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 HA2 PF04408.18 EGO59232.1 - 1.1e-28 99.2 0.1 1.1e-28 99.2 0.1 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGO59232.1 - 1.4e-28 99.0 0.0 9.4e-28 96.3 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.18 EGO59232.1 - 5.7e-13 48.7 0.5 1.5e-12 47.3 0.4 1.7 1 0 0 1 1 1 1 S1 RNA binding domain RimM PF01782.13 EGO59232.1 - 0.048 13.5 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 RimM N-terminal domain Pmp3 PF01679.12 EGO59233.1 - 1.6e-18 66.0 6.4 2.3e-18 65.6 4.5 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Arb1 PF09692.5 EGO59234.1 - 9.9e-145 482.3 0.0 1.2e-144 482.0 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.11 EGO59235.1 - 4.1e-54 183.2 0.0 7.1e-54 182.4 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Nup_retrotrp_bd PF10599.4 EGO59235.1 - 0.049 14.2 0.1 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Retro-transposon transporting motif Clp1 PF06807.9 EGO59236.1 - 4.5e-21 75.5 0.0 7.2e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_17 PF13207.1 EGO59236.1 - 1.9e-05 25.4 0.2 4.9e-05 24.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA PF00004.24 EGO59236.1 - 0.00022 21.4 0.1 0.00042 20.5 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGO59236.1 - 0.00029 21.1 0.1 0.00065 20.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGO59236.1 - 0.00077 19.4 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EGO59236.1 - 0.0015 17.6 0.1 0.0026 16.8 0.1 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus MobB PF03205.9 EGO59236.1 - 0.0018 18.0 0.0 0.0042 16.8 0.0 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EGO59236.1 - 0.0018 17.9 0.5 0.0044 16.7 0.3 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EGO59236.1 - 0.0031 17.2 0.0 0.0063 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGO59236.1 - 0.0042 17.2 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGO59236.1 - 0.0044 16.4 0.1 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 EGO59236.1 - 0.0067 16.0 0.1 0.017 14.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_10 PF12846.2 EGO59236.1 - 0.0084 15.5 0.1 0.033 13.6 0.1 1.9 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 EGO59236.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EGO59236.1 - 0.011 15.6 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGO59236.1 - 0.012 14.8 0.2 0.024 13.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.12 EGO59236.1 - 0.013 15.1 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 EGO59236.1 - 0.026 14.7 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EGO59236.1 - 0.038 13.8 0.1 0.038 13.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EGO59236.1 - 0.05 13.5 0.0 0.34 10.8 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.1 EGO59236.1 - 0.054 12.8 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGO59236.1 - 0.095 11.7 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.5 EGO59236.1 - 0.11 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Git3 PF11710.3 EGO59237.1 - 2.1e-54 184.1 10.9 3.7e-54 183.3 7.6 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EGO59237.1 - 4.6e-28 96.8 0.4 9.1e-28 95.8 0.3 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7TM_GPCR_Srsx PF10320.4 EGO59237.1 - 0.0012 18.1 0.2 0.002 17.3 0.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx GATase PF00117.23 EGO59238.1 - 1.5e-11 44.1 0.1 2.5e-11 43.3 0.1 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGO59238.1 - 0.094 12.1 0.4 0.47 9.8 0.3 2.2 1 1 0 1 1 1 0 Peptidase C26 DHHA2 PF02833.9 EGO59239.1 - 2.8e-29 101.9 0.0 4e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EGO59239.1 - 9.7e-11 41.5 0.0 2.1e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 DHH family Oligomerisation PF02410.10 EGO59240.1 - 7.4e-06 25.9 0.0 0.00011 22.1 0.0 2.7 2 1 0 2 2 2 1 Oligomerisation domain DUF2509 PF10713.4 EGO59240.1 - 0.031 14.0 0.1 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) RNA_pol PF00940.14 EGO59241.1 - 3.9e-169 562.4 0.0 6.4e-169 561.6 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EGO59241.1 - 1.6e-81 274.0 0.3 3.4e-81 272.9 0.2 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal tRNA_bind PF01588.15 EGO59242.1 - 5.2e-23 80.6 0.6 4.2e-22 77.8 0.4 2.2 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EGO59242.1 - 5.7e-06 26.7 0.0 1.2e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO59242.1 - 0.00073 19.4 0.2 0.0016 18.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO59242.1 - 0.0016 18.3 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_60s PF00428.14 EGO59242.1 - 0.078 13.3 3.6 0.33 11.3 2.5 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein SNF2_N PF00176.18 EGO59243.1 - 5e-72 242.2 1.3 6.7e-72 241.8 0.3 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO59243.1 - 1.6e-16 59.9 0.0 7.9e-16 57.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO59243.1 - 1.1e-06 28.5 0.3 7.4e-06 25.9 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGO59243.1 - 0.00052 19.5 0.1 0.003 17.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Glycos_transf_2 PF00535.21 EGO59243.1 - 0.011 15.3 0.1 0.034 13.8 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 MFS_1 PF07690.11 EGO59244.1 - 4.5e-36 124.3 40.5 1.1e-35 122.9 18.3 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 EGO59245.1 - 1.1e-22 80.7 6.0 8.2e-20 71.3 0.4 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF4528 PF15031.1 EGO59245.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) ADH_zinc_N PF00107.21 EGO59246.1 - 8.9e-24 83.4 0.1 1.4e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO59246.1 - 9e-20 71.8 0.0 1.7e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO59246.1 - 4.2e-08 32.9 0.0 9.2e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 EGO59246.1 - 0.014 14.5 0.1 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MoCF_biosynth PF00994.19 EGO59246.1 - 0.036 13.4 0.1 0.069 12.5 0.1 1.4 1 0 0 1 1 1 0 Probable molybdopterin binding domain DUF382 PF04037.8 EGO59247.1 - 0.12 12.1 2.6 4 7.2 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF382) GFA PF04828.9 EGO59248.1 - 4.4e-15 55.3 0.8 6.2e-15 54.9 0.5 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Guanylate_kin PF00625.16 EGO59249.1 - 3e-60 202.8 0.0 3.3e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 EGO59249.1 - 1e-06 28.6 0.0 3.1e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO59249.1 - 1e-05 25.8 0.1 3.6e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO59249.1 - 0.0012 19.6 0.4 0.0052 17.6 0.3 2.0 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGO59249.1 - 0.0027 16.9 0.0 0.0049 16.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGO59249.1 - 0.0039 17.3 0.0 0.0092 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGO59249.1 - 0.0055 16.6 0.0 0.02 14.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO59249.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EGO59249.1 - 0.018 15.3 0.0 0.022 15.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EGO59249.1 - 0.041 13.8 0.1 0.38 10.6 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EGO59249.1 - 0.047 13.2 0.1 0.11 12.0 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 EGO59249.1 - 0.056 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGO59249.1 - 0.067 13.1 0.0 0.086 12.8 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 EGO59249.1 - 0.11 12.2 0.1 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF4095 PF13338.1 EGO59249.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) AAA_23 PF13476.1 EGO59249.1 - 0.19 12.0 1.5 1.5 9.1 1.0 2.0 1 1 0 1 1 1 0 AAA domain Pyr_redox_3 PF13738.1 EGO59251.1 - 9.5e-21 74.7 0.0 2e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EGO59251.1 - 3.1e-14 52.1 0.0 1.3e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EGO59251.1 - 1e-12 47.6 0.0 3.8e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGO59251.1 - 2.4e-06 27.4 0.0 8.1e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO59251.1 - 1.1e-05 25.3 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO59251.1 - 3.4e-05 23.6 0.0 0.00079 19.2 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EGO59251.1 - 0.024 13.5 0.1 3.7 6.3 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGO59251.1 - 0.075 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EGO59251.1 - 0.097 13.0 0.1 2.2 8.7 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GerE PF00196.14 EGO59251.1 - 0.15 11.3 0.0 0.36 10.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family PPE PF00823.14 EGO59252.1 - 0.4 10.4 5.7 1.7 8.4 3.9 1.8 1 1 0 1 1 1 0 PPE family DUF624 PF04854.9 EGO59253.1 - 0.57 10.0 2.7 1 9.2 1.8 1.5 1 1 1 2 2 2 0 Protein of unknown function, DUF624 DUF3638 PF12340.3 EGO59255.1 - 9.6e-103 342.0 0.2 1.9e-102 341.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EGO59255.1 - 2.2e-15 55.4 0.1 4.7e-15 54.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) TENA_THI-4 PF03070.11 EGO59257.1 - 2.4e-10 40.5 0.0 3.7e-08 33.3 0.0 2.7 2 1 1 3 3 3 2 TENA/THI-4/PQQC family Mito_fiss_reg PF05308.6 EGO59258.1 - 0.071 12.4 0.3 0.071 12.4 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator TFR_dimer PF04253.10 EGO59262.1 - 1.7e-27 95.4 0.0 2.8e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EGO59262.1 - 1.8e-18 66.9 0.0 4e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EGO59262.1 - 0.00025 20.6 0.0 0.00049 19.7 0.0 1.5 1 0 0 1 1 1 1 PA domain Vps35 PF03635.12 EGO59263.1 - 0 1034.5 0.2 0 1034.3 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ank_2 PF12796.2 EGO59264.1 - 2.4e-45 152.7 0.9 2.4e-10 40.6 0.0 7.2 4 2 2 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EGO59264.1 - 2.5e-37 124.8 18.9 3.8e-05 23.2 0.0 12.8 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.1 EGO59264.1 - 1e-24 85.9 20.0 6.3e-05 23.0 0.0 11.2 7 4 3 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO59264.1 - 6.1e-23 78.6 20.5 0.02 15.0 0.0 11.6 14 0 0 14 14 14 7 Ankyrin repeat Ank_4 PF13637.1 EGO59264.1 - 8.4e-18 64.3 11.7 0.012 16.1 0.0 10.0 6 3 6 12 12 12 8 Ankyrin repeats (many copies) F-box-like PF12937.2 EGO59264.1 - 0.0011 18.6 0.1 0.0022 17.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO59264.1 - 0.037 13.6 0.3 0.086 12.5 0.2 1.5 1 0 0 1 1 1 0 F-box domain E1-E2_ATPase PF00122.15 EGO59265.1 - 1.1e-17 63.8 0.0 2.3e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGO59265.1 - 1.8e-14 54.7 0.3 6.5e-11 43.0 0.1 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO59265.1 - 5.6e-12 45.4 0.0 1.9e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGO59265.1 - 2e-11 44.3 0.2 4.6e-10 39.9 0.2 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGO59265.1 - 0.00091 18.8 0.0 0.0049 16.4 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Lipase_GDSL_2 PF13472.1 EGO59267.1 - 4.9e-16 59.3 0.5 7.1e-16 58.8 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGO59267.1 - 2.1e-15 57.2 0.1 2.9e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EGO59267.1 - 2.6e-06 27.2 0.5 3.7e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family CoA_trans PF01144.18 EGO59267.1 - 0.046 12.8 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase TrwB_AAD_bind PF10412.4 EGO59268.1 - 0.071 11.7 0.1 0.087 11.4 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain TFIIB PF00382.14 EGO59269.1 - 2.1e-30 104.3 4.9 2.3e-15 56.1 0.5 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EGO59269.1 - 3.4e-19 68.8 0.6 3.4e-19 68.8 0.4 4.5 3 1 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 EGO59269.1 - 5.5e-05 22.7 0.8 0.12 11.9 0.1 2.4 1 1 1 2 2 2 2 Cyclin, N-terminal domain BTB PF00651.26 EGO59270.1 - 2.5e-05 24.2 0.0 6.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain SK_channel PF03530.9 EGO59271.1 - 0.025 14.4 0.2 0.059 13.2 0.2 1.6 1 0 0 1 1 1 0 Calcium-activated SK potassium channel PsaM PF07465.8 EGO59271.1 - 0.049 13.2 1.0 0.12 11.9 0.7 1.7 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) DUF1345 PF07077.6 EGO59271.1 - 0.12 11.9 2.9 0.11 12.0 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1345) Peptidase_S24 PF00717.18 EGO59272.1 - 9.9e-08 31.5 0.0 1.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like AgrD PF05931.6 EGO59273.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Staphylococcal AgrD protein HLH PF00010.21 EGO59274.1 - 1.1e-11 44.2 0.1 1.1e-11 44.2 0.1 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain MAGE_N PF12440.3 EGO59274.1 - 0.0083 16.3 1.6 0.0083 16.3 1.1 2.6 2 0 0 2 2 2 1 Melanoma associated antigen family N terminal DUF3287 PF11690.3 EGO59274.1 - 0.022 14.8 0.2 0.022 14.8 0.1 2.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3287) He_PIG PF05345.7 EGO59274.1 - 0.039 13.9 4.2 0.057 13.4 1.8 2.1 2 0 0 2 2 2 0 Putative Ig domain RabGAP-TBC PF00566.13 EGO59277.1 - 1.5e-35 122.6 0.2 3.8e-32 111.5 0.1 3.1 2 1 0 2 2 2 2 Rab-GTPase-TBC domain UQ_con PF00179.21 EGO59279.1 - 2.7e-39 133.8 0.0 3.2e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO59279.1 - 0.00012 21.8 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGO59279.1 - 0.017 15.0 0.1 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 EGO59279.1 - 0.069 12.8 0.1 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain TPR_11 PF13414.1 EGO59280.1 - 0.00013 21.5 9.9 0.11 12.1 0.3 4.7 5 0 0 5 5 5 3 TPR repeat TPR_17 PF13431.1 EGO59280.1 - 0.0013 18.7 0.5 14 6.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO59280.1 - 0.28 11.5 5.2 29 5.0 0.4 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGO59280.1 - 0.69 10.6 8.6 4.9 7.9 1.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGO59280.1 - 1.4 9.8 12.2 11 6.9 0.3 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 EGO59281.1 - 8.7e-161 535.1 0.0 1.1e-160 534.7 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 EGO59281.1 - 4.3e-07 30.0 0.4 0.56 11.0 0.0 5.2 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGO59281.1 - 3.5e-05 23.2 0.4 0.42 10.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGO59281.1 - 0.00015 21.3 0.1 0.72 9.5 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_9 PF13371.1 EGO59281.1 - 0.00022 21.0 0.5 0.042 13.6 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO59281.1 - 0.00025 20.6 0.1 0.61 9.9 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGO59281.1 - 0.00062 19.4 0.7 0.27 11.2 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGO59281.1 - 0.0012 19.0 0.0 1.9 8.9 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGO59281.1 - 0.0055 17.0 0.2 11 6.7 0.0 3.9 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGO59281.1 - 0.012 16.2 0.3 11 6.8 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EGO59281.1 - 0.012 15.7 0.6 7.9 6.6 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EGO59281.1 - 0.016 14.7 0.2 6.9 6.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGO59281.1 - 0.049 13.5 0.2 4.2 7.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2007 PF09413.5 EGO59281.1 - 0.079 12.7 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) PPR_3 PF13812.1 EGO59281.1 - 0.086 13.1 0.0 14 6.2 0.0 3.6 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Aldo_ket_red PF00248.16 EGO59282.1 - 3.1e-54 183.7 0.0 3.7e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TcpQ PF10671.4 EGO59282.1 - 0.00066 19.5 0.2 0.0016 18.3 0.1 1.5 1 0 0 1 1 1 1 Toxin co-regulated pilus biosynthesis protein Q HIT PF01230.18 EGO59283.1 - 3.6e-18 65.9 0.0 5.3e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGO59283.1 - 2.6e-08 34.1 0.0 3.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EGO59283.1 - 0.015 14.9 0.1 0.041 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 DNA_RNApol_7kD PF03604.8 EGO59284.1 - 3.3e-15 55.2 3.0 4.3e-15 54.8 2.1 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 EGO59284.1 - 0.0057 16.4 0.2 0.0087 15.8 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon Zn-ribbon_8 PF09723.5 EGO59284.1 - 0.018 14.9 0.5 0.03 14.2 0.3 1.3 1 0 0 1 1 1 0 Zinc ribbon domain HypA PF01155.14 EGO59284.1 - 0.029 14.0 0.3 0.036 13.7 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family GFA PF04828.9 EGO59284.1 - 0.05 13.5 0.4 5.9 6.9 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-ISL3 PF14690.1 EGO59284.1 - 0.22 11.5 0.1 0.22 11.5 0.1 1.7 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 ATP_bind_1 PF03029.12 EGO59285.1 - 5.8e-75 251.8 0.0 7.8e-75 251.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Miro PF08477.8 EGO59285.1 - 0.0001 22.7 0.0 0.19 12.2 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 EGO59285.1 - 0.00011 21.8 0.7 0.00078 18.9 0.5 2.0 1 1 0 1 1 1 1 AAA-like domain ArgK PF03308.11 EGO59285.1 - 0.00021 20.1 0.0 0.17 10.6 0.0 2.3 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 EGO59285.1 - 0.00024 21.0 0.0 0.00052 19.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EGO59285.1 - 0.00061 18.5 1.2 0.013 14.2 0.0 2.8 3 0 0 3 3 3 1 G-protein alpha subunit GTP_EFTU PF00009.22 EGO59285.1 - 0.0008 18.8 0.0 0.04 13.3 0.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EGO59285.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO59285.1 - 0.0011 19.1 0.0 0.0032 17.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGO59285.1 - 0.0014 17.8 0.1 0.003 16.6 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.17 EGO59285.1 - 0.0014 17.5 0.1 0.0027 16.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 EGO59285.1 - 0.0018 18.1 0.8 0.0058 16.5 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EGO59285.1 - 0.0045 17.7 1.5 0.022 15.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.13 EGO59285.1 - 0.0059 15.8 0.1 0.14 11.4 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B NACHT PF05729.7 EGO59285.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Arf PF00025.16 EGO59285.1 - 0.012 14.8 0.0 0.5 9.5 0.0 2.6 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_30 PF13604.1 EGO59285.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EGO59285.1 - 0.018 14.6 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.17 EGO59285.1 - 0.028 13.8 0.0 0.084 12.3 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 EGO59285.1 - 0.028 14.7 0.0 3.2 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGO59285.1 - 0.037 13.9 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EGO59285.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EGO59285.1 - 0.078 12.6 0.0 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase cobW PF02492.14 EGO59285.1 - 0.099 12.0 0.0 0.63 9.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain U1snRNP70_N PF12220.3 EGO59285.1 - 0.1 12.9 1.9 0.3 11.4 1.3 1.7 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal UPF0079 PF02367.12 EGO59285.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EGO59285.1 - 0.63 10.3 6.4 0.69 10.2 0.0 2.6 2 0 0 2 2 1 0 AAA domain CwfJ_C_2 PF04676.9 EGO59287.1 - 2.1e-25 89.0 0.0 2.1e-25 89.0 0.0 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 EGO59287.1 - 7.9e-25 86.8 0.0 1.6e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 FumaraseC_C PF10415.4 EGO59287.1 - 0.0012 18.8 1.8 0.6 10.2 0.1 2.7 2 0 0 2 2 2 2 Fumarase C C-terminus DEAD PF00270.24 EGO59288.1 - 9.4e-47 158.6 0.0 1.9e-46 157.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO59288.1 - 4.2e-26 90.6 0.0 7.8e-26 89.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO59288.1 - 2.9e-06 27.2 0.1 4.6e-05 23.3 0.0 2.8 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EGO59288.1 - 0.023 14.4 0.9 0.046 13.4 0.1 2.0 2 0 0 2 2 2 0 Part of AAA domain Borrelia_P83 PF05262.6 EGO59288.1 - 0.12 10.6 5.1 0.17 10.1 3.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Brix PF04427.13 EGO59289.1 - 1.2e-57 194.6 0.0 1.8e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF2681 PF10883.3 EGO59289.1 - 1.9 8.7 8.9 6.5 7.0 6.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Glyco_hydro_18 PF00704.23 EGO59293.1 - 2.6e-19 69.8 3.4 7.6e-19 68.3 0.2 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 CBM_1 PF00734.13 EGO59293.1 - 5.1e-11 42.0 8.1 1.5e-10 40.5 5.6 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain FtsX PF02687.16 EGO59293.1 - 0.67 9.7 3.8 4.8 6.9 0.1 2.4 2 0 0 2 2 2 0 FtsX-like permease family Rubella_Capsid PF05750.6 EGO59294.1 - 0.54 9.6 7.0 0.84 8.9 4.8 1.3 1 0 0 1 1 1 0 Rubella capsid protein TPR_19 PF14559.1 EGO59295.1 - 9.1e-06 25.9 1.0 0.095 13.0 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGO59295.1 - 0.00099 18.7 0.0 1.9 8.1 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 EGO59295.1 - 0.0011 19.5 9.5 2.3 9.0 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGO59295.1 - 0.0083 15.9 0.4 27 4.9 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EGO59295.1 - 0.055 13.6 0.0 0.73 10.0 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.9 EGO59295.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.5 1 1 0 1 1 1 0 Coatomer epsilon subunit SUR7 PF06687.7 EGO59296.1 - 6.3e-11 42.2 12.5 9.8e-11 41.6 8.7 1.3 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EGO59296.1 - 0.49 10.0 16.9 0.037 13.7 7.7 1.9 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Clc-like PF07062.7 EGO59296.1 - 0.68 9.1 7.2 1 8.5 5.0 1.3 1 0 0 1 1 1 0 Clc-like Cu_bind_like PF02298.12 EGO59297.1 - 8.3e-05 22.3 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.15 EGO59297.1 - 0.00018 21.7 0.1 0.00033 20.8 0.1 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Nucleoporin_FG PF13634.1 EGO59297.1 - 0.21 11.7 14.2 0.36 11.0 9.8 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region RAP1 PF07218.6 EGO59297.1 - 9.6 4.1 9.5 12 3.8 6.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cyclin_N PF00134.18 EGO59298.1 - 2.4e-05 23.8 0.0 4.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Esterase_phd PF10503.4 EGO59299.1 - 7.9e-17 61.2 0.0 1.3e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EGO59299.1 - 7.2e-06 25.3 0.1 1.3e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EGO59299.1 - 4.9e-05 22.8 0.1 5.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 EGO59299.1 - 0.0037 17.1 0.0 0.0061 16.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO59299.1 - 0.0046 16.7 0.0 0.0062 16.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGO59299.1 - 0.0054 16.3 0.0 0.0077 15.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EGO59299.1 - 0.0095 15.5 0.1 0.015 14.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold GPI-anchored PF10342.4 EGO59300.1 - 2.5e-15 56.6 2.8 2.5e-15 56.6 2.0 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EGO59300.1 - 0.12 11.8 1.2 0.25 10.7 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Ifi-6-16 PF06140.8 EGO59304.1 - 0.5 10.1 26.1 1.3 8.8 18.1 1.7 1 1 1 2 2 2 0 Interferon-induced 6-16 family EI24 PF07264.6 EGO59305.1 - 0.036 13.5 0.4 0.072 12.5 0.0 1.6 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Ifi-6-16 PF06140.8 EGO59306.1 - 0.0028 17.4 28.9 0.003 17.2 19.2 1.8 1 1 0 1 1 1 1 Interferon-induced 6-16 family ATP-synt_B PF00430.13 EGO59306.1 - 0.047 13.4 1.7 0.066 13.0 0.5 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) EspB PF05802.6 EGO59306.1 - 0.053 12.4 0.1 0.053 12.4 0.1 2.1 2 0 0 2 2 2 0 Enterobacterial EspB protein Phasin PF05597.6 EGO59306.1 - 0.07 12.8 1.5 0.17 11.6 0.5 1.9 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Prominin PF05478.6 EGO59306.1 - 0.16 9.4 0.1 0.37 8.2 0.0 1.4 1 1 1 2 2 2 0 Prominin Apolipoprotein PF01442.13 EGO59306.1 - 0.16 11.4 1.9 0.47 9.9 1.3 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain BMFP PF04380.8 EGO59306.1 - 0.17 12.0 2.2 10 6.3 0.0 3.3 1 1 3 4 4 4 0 Membrane fusogenic activity DUF883 PF05957.8 EGO59306.1 - 0.56 10.6 14.9 1.9 8.9 0.1 4.0 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) ISG65-75 PF11727.3 EGO59306.1 - 1.4 7.8 4.9 7.1 5.5 2.3 2.3 1 1 1 2 2 2 0 Invariant surface glycoprotein Ifi-6-16 PF06140.8 EGO59307.1 - 7.1e-15 54.5 24.2 9.5e-08 31.7 6.0 2.8 2 0 0 2 2 2 2 Interferon-induced 6-16 family Kp4 PF09044.5 EGO59307.1 - 0.22 11.3 1.0 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 Kp4 AdoHcyase_NAD PF00670.16 EGO59307.1 - 1.2 8.9 4.4 5.2 6.8 0.0 2.9 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ifi-6-16 PF06140.8 EGO59308.1 - 2.5e-05 23.9 5.5 7e-05 22.5 3.8 1.8 1 1 0 1 1 1 1 Interferon-induced 6-16 family DUF2715 PF10895.3 EGO59309.1 - 0.046 13.2 0.2 0.33 10.4 0.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2715) DNA_binding_1 PF01035.15 EGO59309.1 - 0.08 12.7 7.2 1.4 8.7 0.3 3.6 1 1 3 4 4 4 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Ribosomal_L2_C PF03947.13 EGO59309.1 - 0.24 11.2 1.9 16 5.2 0.2 2.4 1 1 0 2 2 2 0 Ribosomal Proteins L2, C-terminal domain Virulence_fact PF13769.1 EGO59309.1 - 0.26 11.1 2.2 2.6 7.9 0.0 2.3 1 1 1 2 2 2 0 Virulence factor NUC153 PF08159.7 EGO59311.1 - 1.6e-14 53.1 7.2 2.8e-14 52.3 0.7 3.3 3 0 0 3 3 3 2 NUC153 domain FBPase PF00316.15 EGO59313.1 - 1.7e-49 168.3 0.0 4.8e-49 166.9 0.0 1.6 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase DUF2723 PF11028.3 EGO59313.1 - 0.046 13.2 0.6 0.068 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) Hce2 PF14856.1 EGO59315.1 - 6.1e-26 90.1 0.3 1.1e-25 89.3 0.2 1.4 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor AFG1_ATPase PF03969.11 EGO59316.1 - 1.4e-96 323.4 0.0 8.6e-92 307.7 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EGO59316.1 - 2.8e-05 24.1 4.5 0.027 14.4 0.0 3.5 3 1 0 4 4 4 2 AAA ATPase domain Bac_DnaA PF00308.13 EGO59316.1 - 3.8e-05 23.4 0.1 0.02 14.5 0.0 2.6 2 1 0 2 2 2 2 Bacterial dnaA protein AAA PF00004.24 EGO59316.1 - 0.00063 19.9 0.0 0.0097 16.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGO59316.1 - 0.001 18.9 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGO59316.1 - 0.0019 18.3 0.0 0.0093 16.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EGO59316.1 - 0.0028 17.3 0.0 0.0071 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EGO59316.1 - 0.0037 17.4 0.3 0.034 14.3 0.0 2.6 2 1 0 2 2 2 1 RNA helicase AAA_24 PF13479.1 EGO59316.1 - 0.034 13.7 0.3 3.5 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EGO59316.1 - 0.071 13.1 0.0 0.71 9.9 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain UvrD-helicase PF00580.16 EGO59316.1 - 0.075 12.3 0.0 0.15 11.3 0.0 1.4 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain NACHT PF05729.7 EGO59316.1 - 0.097 12.3 0.0 0.3 10.7 0.0 2.0 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EGO59316.1 - 0.13 12.5 0.0 5.7 7.2 0.0 2.8 3 0 0 3 3 3 0 ABC transporter Arch_ATPase PF01637.13 EGO59316.1 - 0.16 11.6 0.0 0.53 9.9 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase DUF1295 PF06966.7 EGO59317.1 - 8.6e-15 54.6 0.2 1.2e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 EGO59317.1 - 1e-06 27.6 1.1 1e-06 27.6 0.8 1.5 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.11 EGO59317.1 - 1.6e-05 24.7 0.1 2.4e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EGO59317.1 - 0.076 13.1 1.3 0.23 11.5 0.4 2.2 1 1 1 2 2 2 0 Phospholipid methyltransferase Glyco_tranf_2_2 PF10111.4 EGO59317.1 - 0.093 11.7 0.1 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 ICMT PF04140.9 EGO59317.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family SRP-alpha_N PF04086.8 EGO59317.1 - 1.6 8.0 5.8 2.3 7.5 4.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SelP_N PF04592.9 EGO59317.1 - 4 6.7 7.7 5.9 6.1 5.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_M28 PF04389.12 EGO59318.1 - 8.2e-26 90.8 0.1 1.4e-25 90.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EGO59318.1 - 8.8e-06 25.3 0.0 1.9e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 DUF999 PF06198.6 EGO59318.1 - 0.028 14.2 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF999) PLDc_2 PF13091.1 EGO59319.1 - 2.6e-15 56.2 0.0 4.3e-08 32.9 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EGO59319.1 - 0.00017 21.2 3.3 0.15 11.9 0.0 3.8 4 0 0 4 4 4 3 Phospholipase D Active site motif DUF3632 PF12311.3 EGO59320.1 - 7.5e-12 45.4 2.7 2.3e-05 24.3 1.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3632) DUF2664 PF10867.3 EGO59321.1 - 0.056 14.0 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) Abhydrolase_1 PF00561.15 EGO59322.1 - 0.0042 16.6 0.0 0.0081 15.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EGO59322.1 - 0.1 12.1 0.0 0.43 10.1 0.0 1.8 1 1 0 1 1 1 0 PGAP1-like protein Oxidored_molyb PF00174.14 EGO59323.1 - 1.4e-49 167.7 0.0 5.4e-49 165.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EGO59323.1 - 3.7e-24 84.8 0.8 6.1e-24 84.1 0.6 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain SLBB PF10531.4 EGO59323.1 - 0.074 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 SLBB domain CAP59_mtransfer PF11735.3 EGO59324.1 - 7.7e-88 293.7 0.0 1.1e-87 293.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DEAD PF00270.24 EGO59325.1 - 4.1e-19 68.6 0.0 1e-18 67.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EGO59325.1 - 1.5e-08 34.7 0.0 1.5e-07 31.4 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGO59325.1 - 6.7e-08 32.2 0.1 1.4e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 EGO59325.1 - 0.0049 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein Lentivirus_VIF PF05851.6 EGO59325.1 - 0.11 11.1 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) CAP PF00188.21 EGO59326.1 - 1.9e-16 60.6 2.2 2.6e-16 60.2 1.6 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family HD_3 PF13023.1 EGO59327.1 - 3.7e-48 163.4 0.2 5e-48 162.9 0.1 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.17 EGO59327.1 - 0.0044 17.0 0.1 0.015 15.2 0.1 1.9 1 1 0 1 1 1 1 HD domain LicD PF04991.8 EGO59327.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 LicD family AA_permease PF00324.16 EGO59329.1 - 4.2e-100 335.3 40.7 5.1e-100 335.0 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO59329.1 - 2.3e-27 95.6 41.6 2.7e-27 95.3 28.8 1.1 1 0 0 1 1 1 1 Amino acid permease HD PF01966.17 EGO59331.1 - 4.6e-06 26.6 0.0 7.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 HD domain SelB-wing_2 PF09106.6 EGO59332.1 - 0.012 15.5 0.0 0.04 13.8 0.0 1.9 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Nucleoporin_C PF03177.9 EGO59335.1 - 1.9e-146 488.9 1.9 2.9e-146 488.4 1.3 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EGO59335.1 - 1.7e-94 316.9 0.0 2.4e-94 316.4 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like adh_short PF00106.20 EGO59336.1 - 1.5e-23 83.5 0.0 2.1e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO59336.1 - 6.7e-13 48.9 0.0 9.1e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO59336.1 - 6.2e-09 35.7 0.0 1.3e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO59336.1 - 0.00074 19.5 0.1 0.0029 17.6 0.0 2.0 1 1 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 EGO59336.1 - 0.021 13.7 0.0 0.054 12.4 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase Epimerase PF01370.16 EGO59336.1 - 0.092 12.1 0.0 0.18 11.1 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GalP_UDP_transf PF01087.17 EGO59337.1 - 2.1e-69 233.2 1.0 2.2e-68 229.9 0.2 2.1 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EGO59337.1 - 1.2e-57 194.0 0.1 2.3e-57 193.1 0.1 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 EGO59337.1 - 0.00016 22.1 0.0 0.0069 16.8 0.0 2.5 2 1 0 2 2 2 1 HIT domain Glyco_hydro_8 PF01270.12 EGO59337.1 - 0.077 11.6 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 SWIRM PF04433.12 EGO59338.1 - 1.1e-12 47.8 0.0 4.1e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 EGO59338.1 - 5.4e-10 38.6 5.3 1e-09 37.7 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EGO59338.1 - 3.6e-08 33.3 0.0 1.5e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain SHOCT PF09851.4 EGO59338.1 - 0.017 14.5 0.5 0.063 12.7 0.4 2.0 1 0 0 1 1 1 0 Short C-terminal domain zf-C3HC4_2 PF13923.1 EGO59338.1 - 0.75 9.8 4.8 1.8 8.6 3.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mg_trans_NIPA PF05653.9 EGO59339.1 - 1.7e-89 299.7 24.7 2.3e-89 299.3 17.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EGO59339.1 - 2.4e-06 27.7 5.2 2.4e-06 27.7 3.6 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EGO59339.1 - 0.0037 17.2 8.0 0.0037 17.2 5.5 3.2 3 1 0 3 3 3 1 EamA-like transporter family U-box PF04564.10 EGO59340.1 - 1.7e-19 69.5 0.1 3.2e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 EGO59340.1 - 5.6e-16 57.9 0.6 5.2e-14 51.6 0.1 2.7 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EGO59340.1 - 3.8e-08 32.6 2.6 0.0032 17.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGO59340.1 - 4.7e-07 29.2 2.9 0.11 12.4 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGO59340.1 - 7.1e-05 22.6 2.2 0.71 9.8 0.1 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGO59340.1 - 0.018 14.8 0.5 15 5.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGO59340.1 - 0.068 12.9 1.4 23 5.0 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat zf-Nse PF11789.3 EGO59340.1 - 0.098 12.1 0.0 0.31 10.5 0.0 1.9 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TPR_16 PF13432.1 EGO59340.1 - 0.21 12.3 1.5 7.5 7.3 0.0 2.9 2 1 1 3 3 2 0 Tetratricopeptide repeat Prog_receptor PF02161.10 EGO59340.1 - 0.23 10.2 1.4 0.29 9.9 1.0 1.1 1 0 0 1 1 1 0 Progesterone receptor DUF883 PF05957.8 EGO59340.1 - 0.95 9.9 5.0 0.51 10.7 1.4 2.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) TPR_10 PF13374.1 EGO59340.1 - 2 8.4 4.7 7.1 6.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat RRF PF01765.14 EGO59340.1 - 3.6 7.0 6.9 6 6.3 4.8 1.3 1 0 0 1 1 1 0 Ribosome recycling factor SH3_9 PF14604.1 EGO59341.1 - 7.1e-10 38.3 0.0 1.1e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO59341.1 - 3e-05 23.2 0.0 4.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGO59341.1 - 7.2e-05 22.1 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Protocadherin PF08374.6 EGO59341.1 - 0.0015 18.2 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Protocadherin Herpes_gE PF02480.11 EGO59341.1 - 0.035 12.3 0.1 0.06 11.5 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Cyt_c_ox_IV PF12270.3 EGO59341.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Cytokin-bind PF09265.5 EGO59341.1 - 0.29 10.2 0.6 0.42 9.7 0.4 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Gar1 PF04410.9 EGO59342.1 - 8.6e-46 155.2 1.3 8.6e-46 155.2 0.9 2.8 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region Glyco_transf_22 PF03901.12 EGO59343.1 - 1.3e-85 288.0 17.8 1.5e-85 287.7 12.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HET PF06985.6 EGO59344.1 - 6.1e-21 75.0 0.0 1.3e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Oxidored_FMN PF00724.15 EGO59345.1 - 3.8e-98 328.6 0.0 4.3e-98 328.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 EGO59345.1 - 0.064 12.5 0.0 3.5 6.8 0.0 2.6 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel F-box-like PF12937.2 EGO59346.1 - 0.018 14.7 0.0 0.16 11.7 0.0 2.2 1 1 0 1 1 1 0 F-box-like F-box PF00646.28 EGO59346.1 - 0.049 13.3 0.4 13 5.5 0.1 2.4 2 0 0 2 2 2 0 F-box domain tRNA-synt_2b PF00587.20 EGO59348.1 - 2.4e-22 79.3 0.1 4.9e-22 78.3 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 EGO59348.1 - 4e-21 74.7 0.2 8.2e-21 73.6 0.1 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 EGO59348.1 - 2.4e-17 62.6 0.0 5.4e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Peptidase_S49_N PF08496.5 EGO59348.1 - 6.5 6.5 6.7 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Cpn60_TCP1 PF00118.19 EGO59349.1 - 1.3e-143 479.1 14.9 1.5e-143 478.9 10.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CopK PF11525.3 EGO59350.1 - 0.1 12.2 0.3 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 Copper resistance protein K MFS_1 PF07690.11 EGO59351.1 - 3.9e-28 98.1 64.8 4.2e-18 65.1 26.8 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EGO59351.1 - 1.4e-11 43.4 17.3 3.1e-10 39.0 3.8 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein DUF3767 PF12597.3 EGO59351.1 - 0.23 11.1 0.9 5.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) SNF2_N PF00176.18 EGO59352.1 - 5.1e-45 153.5 0.0 4.1e-44 150.5 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO59352.1 - 9.5e-10 38.2 1.3 1.8e-09 37.2 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO59352.1 - 2.2e-08 34.1 0.1 6.3e-07 29.3 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TEX33 PF15400.1 EGO59352.1 - 0.0061 16.9 0.4 0.02 15.3 0.0 2.0 2 0 0 2 2 2 1 Testis-expressed sequence 33 protein family zf-RING_2 PF13639.1 EGO59352.1 - 0.013 15.2 4.4 0.028 14.2 3.1 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EGO59352.1 - 0.051 13.3 5.9 0.096 12.4 4.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGO59352.1 - 0.085 12.9 6.0 0.16 11.9 4.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO59352.1 - 0.15 11.7 3.8 0.32 10.6 2.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2360 PF10152.4 EGO59352.1 - 0.38 11.0 3.3 0.54 10.5 1.2 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Ank_2 PF12796.2 EGO59353.1 - 6.1e-63 209.1 27.1 1.9e-13 50.5 0.1 14.5 10 3 3 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.25 EGO59353.1 - 6.1e-35 117.3 32.1 1.1e-05 25.0 0.0 19.7 22 0 0 22 22 22 9 Ankyrin repeat Ank_3 PF13606.1 EGO59353.1 - 1.5e-26 89.8 20.1 0.00017 21.4 0.0 20.3 26 0 0 26 26 26 5 Ankyrin repeat Ank_4 PF13637.1 EGO59353.1 - 1.3e-23 82.9 20.9 0.016 15.7 0.0 15.8 16 3 2 18 18 18 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO59353.1 - 3.7e-19 68.2 24.1 4.7e-06 26.6 0.0 15.2 14 2 3 17 17 17 4 Ankyrin repeats (many copies) ADH_zinc_N PF00107.21 EGO59354.1 - 2.9e-28 98.0 0.2 4e-28 97.5 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO59354.1 - 8.5e-18 65.4 0.1 1.9e-17 64.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO59354.1 - 2.3e-07 30.5 0.0 8.7e-07 28.6 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EGO59354.1 - 0.064 13.2 3.3 0.12 12.4 0.4 2.2 2 1 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 EGO59355.1 - 4e-44 150.8 0.0 5.8e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EGO59355.1 - 1.7e-24 85.5 0.0 2.9e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EGO59355.1 - 5.8e-15 54.7 0.0 1.5e-14 53.4 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGO59355.1 - 4.5e-13 48.7 0.0 7.5e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGO59355.1 - 5e-13 48.5 0.0 4.8e-11 42.0 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EGO59355.1 - 2.3e-11 43.8 0.0 3.6e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EGO59355.1 - 9.3e-10 37.8 0.0 2.2e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGO59355.1 - 3.1e-09 37.0 0.0 5.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EGO59355.1 - 1.3e-07 31.5 0.0 2.5e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EGO59355.1 - 0.009 15.2 0.0 0.055 12.7 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Methyltransf_18 PF12847.2 EGO59355.1 - 0.025 15.1 0.0 3.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 EGO59355.1 - 0.034 13.5 0.1 0.062 12.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sad1_UNC PF07738.8 EGO59357.1 - 4e-11 42.8 0.0 3.9e-05 23.4 0.0 2.4 1 1 0 2 2 2 2 Sad1 / UNC-like C-terminal DEAD PF00270.24 EGO59358.1 - 8.8e-44 148.9 0.0 1.9e-43 147.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EGO59358.1 - 5.8e-25 86.6 0.1 1.4e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EGO59358.1 - 2.4e-22 78.5 0.0 5.1e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MscS_TM PF12794.2 EGO59358.1 - 2.3 6.7 2.6 3.8 6.0 1.8 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 IBR PF01485.16 EGO59359.1 - 5.8e-13 48.5 8.3 2.8e-12 46.3 1.1 3.7 3 1 0 3 3 3 2 IBR domain DNA_ligase_ZBD PF03119.11 EGO59359.1 - 0.26 11.0 13.4 5.8 6.7 0.1 3.9 3 1 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain OrfB_Zn_ribbon PF07282.6 EGO59359.1 - 0.27 10.9 17.0 0.21 11.2 1.0 3.6 3 1 1 4 4 4 0 Putative transposase DNA-binding domain zf-C3HC4_3 PF13920.1 EGO59359.1 - 1.5 8.5 18.7 0.14 11.8 4.1 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C4_Topoisom PF01396.14 EGO59359.1 - 1.7 8.1 8.1 5.1 6.6 0.0 3.5 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger BTB PF00651.26 EGO59361.1 - 0.023 14.6 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain AA_permease PF00324.16 EGO59363.1 - 3.2e-122 408.2 32.4 3.7e-122 408.0 22.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO59363.1 - 1.6e-29 102.7 36.7 1.9e-29 102.4 25.4 1.0 1 0 0 1 1 1 1 Amino acid permease Sulfate_transp PF00916.15 EGO59365.1 - 3e-87 292.1 7.5 4.6e-87 291.5 5.2 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGO59365.1 - 2.6e-29 100.7 3.0 2.6e-29 100.7 2.1 3.2 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGO59365.1 - 3.7e-09 36.0 0.0 7.3e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain Peptidase_M15_3 PF08291.6 EGO59366.1 - 0.0057 16.4 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M15 PAM2 PF07145.10 EGO59367.1 - 1.1e-05 24.5 0.2 2.5e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Glyco_hydro_16 PF00722.16 EGO59368.1 - 2.6e-19 69.2 0.6 6.6e-19 67.9 0.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EGO59368.1 - 9.8e-11 40.4 0.5 0.00012 20.4 0.0 2.0 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Peptidase_M28 PF04389.12 EGO59369.1 - 2.4e-37 128.4 0.0 3.7e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EGO59369.1 - 4.3e-20 71.2 0.4 4.3e-20 71.2 0.3 1.8 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EGO59369.1 - 5.4e-05 22.7 0.0 9.2e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EGO59369.1 - 0.038 12.7 0.2 0.14 10.8 0.0 1.9 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Mmp37 PF09139.6 EGO59370.1 - 1.2e-135 451.8 0.0 1.7e-135 451.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 MAD PF05557.8 EGO59371.1 - 5.8e-52 176.7 50.9 7.9e-52 176.3 35.3 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Reo_sigmaC PF04582.7 EGO59371.1 - 8.4 5.4 18.7 0.57 9.3 2.7 3.5 2 1 0 3 3 3 0 Reovirus sigma C capsid protein muHD PF10291.4 EGO59372.1 - 2.3e-80 269.4 0.0 3.3e-80 268.9 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EGO59372.1 - 4.3e-11 42.8 0.9 1.2e-09 38.2 0.0 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain FUSC PF04632.7 EGO59372.1 - 0.32 9.3 3.6 1.7 7.0 1.0 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family AAA_13 PF13166.1 EGO59372.1 - 1.3 7.3 7.8 2 6.8 5.4 1.2 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 EGO59372.1 - 7.1 4.3 5.1 12 3.6 3.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.20 EGO59373.1 - 1.7e-33 115.8 0.0 2.2e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO59373.1 - 1.4e-09 37.4 0.0 2.1e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO59373.1 - 0.066 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Toxin_51 PF15531.1 EGO59374.1 - 0.1 12.3 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Putative toxin 51 zf-C2H2_4 PF13894.1 EGO59375.1 - 0.38 11.1 5.0 0.28 11.6 0.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO59375.1 - 0.49 10.8 11.0 0.71 10.3 1.4 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Annexin PF00191.15 EGO59376.1 - 2.2e-67 222.8 5.3 1.4e-20 72.9 0.0 4.2 4 0 0 4 4 4 4 Annexin 2OG-FeII_Oxy PF03171.15 EGO59380.1 - 5.2e-20 71.5 0.0 1e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGO59380.1 - 1.1e-15 58.2 0.0 1.8e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.11 EGO59381.1 - 6.6e-44 150.0 52.0 2.5e-42 144.8 34.9 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO59381.1 - 8.4e-06 24.6 9.0 8.4e-06 24.6 6.2 2.9 1 1 2 3 3 3 1 Sugar (and other) transporter Dispanin PF04505.7 EGO59381.1 - 0.37 10.3 0.0 0.37 10.3 0.0 4.7 4 1 1 5 5 5 0 Interferon-induced transmembrane protein DUF3382 PF11862.3 EGO59381.1 - 0.7 9.8 11.1 0.18 11.7 3.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) RRM_6 PF14259.1 EGO59382.1 - 0.00054 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO59382.1 - 0.00069 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4234 PF14018.1 EGO59382.1 - 0.046 13.4 1.1 0.094 12.4 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Clr5 PF14420.1 EGO59383.1 - 1.8e-20 72.5 2.7 3.4e-20 71.6 1.9 1.5 1 0 0 1 1 1 1 Clr5 domain RRN9 PF10680.4 EGO59383.1 - 0.046 13.4 0.3 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Ish1 PF10281.4 EGO59384.1 - 1.7e-91 299.7 15.3 3.6e-15 55.7 0.0 8.4 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EGO59384.1 - 4.1e-13 48.4 0.0 0.038 13.5 0.0 7.5 9 0 0 9 9 9 4 SAP domain Slx4 PF09494.5 EGO59384.1 - 1.8e-09 37.2 4.4 0.98 9.2 0.0 6.5 7 0 0 7 7 7 3 Slx4 endonuclease HeH PF12949.2 EGO59384.1 - 1.7e-07 30.6 0.0 2.2 7.9 0.0 6.2 7 0 0 7 7 7 2 HeH/LEM domain DUF3612 PF12268.3 EGO59384.1 - 0.00046 20.0 0.1 5.5 6.7 0.0 4.4 4 1 1 5 5 5 2 Protein of unknown function (DUF3612) APC2 PF08672.6 EGO59384.1 - 0.00064 19.9 2.0 64 3.9 0.0 6.2 7 0 0 7 7 7 0 Anaphase promoting complex (APC) subunit 2 LEM PF03020.10 EGO59384.1 - 0.093 12.1 0.0 27 4.3 0.0 4.3 5 0 0 5 5 5 0 LEM domain Homeobox_KN PF05920.6 EGO59384.1 - 0.51 10.0 2.9 2.5 7.8 0.0 3.5 4 0 0 4 4 4 0 Homeobox KN domain DUF2795 PF11387.3 EGO59384.1 - 0.82 9.5 5.5 91 3.0 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2795) AAA PF00004.24 EGO59385.1 - 3.7e-40 137.1 0.0 8.2e-40 136.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGO59385.1 - 0.00024 20.2 0.0 0.00051 19.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGO59385.1 - 0.00027 21.0 0.1 0.014 15.4 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EGO59385.1 - 0.00042 20.0 0.4 0.0018 18.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGO59385.1 - 0.00056 20.0 0.2 0.021 14.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EGO59385.1 - 0.0013 18.6 0.0 0.0094 15.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EGO59385.1 - 0.0021 17.3 0.2 0.044 12.9 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EGO59385.1 - 0.0069 15.5 0.0 0.017 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EGO59385.1 - 0.0095 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EGO59385.1 - 0.011 14.7 0.0 0.024 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 EGO59385.1 - 0.018 14.8 0.4 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EGO59385.1 - 0.023 14.1 0.1 0.047 13.1 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 EGO59385.1 - 0.029 15.1 4.3 0.095 13.5 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EGO59385.1 - 0.038 13.4 1.2 0.32 10.3 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EGO59385.1 - 0.046 13.3 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGO59385.1 - 0.066 13.1 0.0 0.41 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EGO59385.1 - 0.82 9.1 0.0 0.82 9.1 0.0 2.6 2 1 0 2 2 1 0 AAA domain Vfa1 PF08432.5 EGO59385.1 - 7.6 6.5 9.9 17 5.4 6.9 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tic20 PF09685.5 EGO59386.1 - 5.7e-07 29.4 1.3 7.7e-07 29.0 0.9 1.1 1 0 0 1 1 1 1 Tic20-like protein DUF3782 PF12644.2 EGO59386.1 - 0.011 15.4 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Ribosomal_L10 PF00466.15 EGO59387.1 - 0.0033 17.3 0.0 0.51 10.3 0.0 2.9 1 1 0 1 1 1 1 Ribosomal protein L10 tRNA_lig_CPD PF08302.6 EGO59388.1 - 1.9e-88 296.0 0.0 2.8e-88 295.4 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 EGO59388.1 - 5e-79 264.8 0.0 1.6e-78 263.2 0.0 1.8 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.6 EGO59388.1 - 6.7e-63 211.5 0.2 6.4e-62 208.3 0.0 2.2 2 0 0 2 2 2 1 tRNA ligase kinase domain Ank_5 PF13857.1 EGO59389.1 - 1.1e-08 34.9 0.1 1.1e-07 31.9 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGO59389.1 - 3.6e-06 27.3 0.0 2.6e-05 24.5 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO59389.1 - 0.00057 20.1 0.1 0.0014 18.9 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGO59389.1 - 0.025 14.8 0.2 0.41 11.0 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat Ank PF00023.25 EGO59389.1 - 0.034 13.9 0.0 0.24 11.2 0.0 2.4 3 0 0 3 3 3 0 Ankyrin repeat Ribonuc_P_40 PF08584.6 EGO59390.1 - 4.5e-66 222.7 0.0 3.2e-65 219.9 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit UPF0020 PF01170.13 EGO59391.1 - 5e-10 39.2 0.0 3.8e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EGO59391.1 - 7.8e-09 35.5 0.0 1.6e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Chorion_2 PF03964.10 EGO59391.1 - 0.005 17.3 0.4 0.014 15.9 0.3 1.7 1 0 0 1 1 1 1 Chorion family 2 SR-25 PF10500.4 EGO59391.1 - 4.4 6.7 14.9 7.5 5.9 10.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Vac_ImportDeg PF09783.4 EGO59392.1 - 2.8e-70 235.3 0.6 4.1e-70 234.8 0.4 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.9 EGO59393.1 - 2.4e-73 244.5 0.3 2.8e-73 244.3 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.15 EGO59394.1 - 3.8e-97 325.7 3.9 6.7e-97 324.9 2.7 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EGO59394.1 - 4e-62 207.7 0.0 1e-61 206.4 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EGO59394.1 - 8.6e-62 206.9 0.6 1.9e-61 205.8 0.4 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EGO59394.1 - 9.4e-07 29.0 11.1 3.8e-05 23.8 0.0 4.6 3 1 2 5 5 5 3 HEAT repeats Cnd1 PF12717.2 EGO59394.1 - 0.011 15.5 5.9 0.11 12.3 0.0 4.0 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EGO59394.1 - 0.054 13.5 1.5 1.4 9.2 0.0 4.0 5 0 0 5 5 5 0 HEAT repeat ubiquitin PF00240.18 EGO59395.1 - 2.4e-05 23.6 0.1 5.6e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EGO59395.1 - 0.00068 19.2 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGO59395.1 - 0.0088 16.2 1.9 0.045 13.9 0.0 2.4 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EGO59395.1 - 0.05 13.4 0.1 0.05 13.4 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like HCBP_related PF06594.6 EGO59395.1 - 0.79 9.4 4.0 0.47 10.1 0.3 2.5 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain FimP PF09766.4 EGO59395.1 - 7.3 5.5 10.1 13 4.7 7.0 1.3 1 0 0 1 1 1 0 Fms-interacting protein NAD_binding_11 PF14833.1 EGO59396.1 - 1.4e-36 125.2 2.3 5.7e-25 87.7 0.1 2.6 2 1 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EGO59396.1 - 7.5e-33 113.6 0.0 1.4e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pre-SET PF05033.11 EGO59396.1 - 1.3e-22 79.9 5.0 1.3e-22 79.9 3.5 1.8 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.23 EGO59396.1 - 3.9e-19 69.5 0.8 7.2e-18 65.4 0.0 3.0 2 1 0 2 2 2 1 SET domain F420_oxidored PF03807.12 EGO59396.1 - 0.00016 21.9 0.0 0.00065 20.0 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EGO59396.1 - 0.00067 19.3 0.0 0.0018 17.9 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EGO59396.1 - 0.051 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F_bP_aldolase PF01116.15 EGO59397.1 - 1.1e-84 283.9 0.1 1.3e-84 283.7 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Dak1 PF02733.12 EGO59398.1 - 2.7e-109 364.6 0.0 3.9e-109 364.1 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EGO59398.1 - 3.2e-40 137.6 1.8 6.3e-40 136.6 1.3 1.5 1 0 0 1 1 1 1 DAK2 domain LacAB_rpiB PF02502.13 EGO59399.1 - 2.1e-42 144.0 0.7 2.6e-42 143.8 0.5 1.1 1 0 0 1 1 1 1 Ribose/Galactose Isomerase TIM PF00121.13 EGO59400.1 - 1.8e-49 168.0 0.0 2.4e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase NAD_binding_10 PF13460.1 EGO59401.1 - 6.5e-08 32.7 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGO59401.1 - 1.1e-07 31.3 0.0 1.8e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family HSP70 PF00012.15 EGO59403.1 - 4.8e-14 51.2 0.1 2.3e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EGO59403.1 - 9.2e-05 21.1 0.1 0.0051 15.4 0.1 2.8 2 1 0 2 2 2 1 MreB/Mbl protein MIB_HERC2 PF06701.8 EGO59403.1 - 0.18 11.7 0.9 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 Mib_herc2 Glyco_hydro_30 PF02055.11 EGO59404.1 - 9e-50 169.2 0.9 1.2e-49 168.8 0.6 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF3050 PF11251.3 EGO59404.1 - 0.0001 21.6 0.0 0.00043 19.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3050) Glyco_hydr_30_2 PF14587.1 EGO59404.1 - 0.0037 16.2 0.0 0.0073 15.2 0.0 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Nop14 PF04147.7 EGO59405.1 - 0.047 11.6 39.8 0.0067 14.4 6.8 2.3 2 0 0 2 2 2 0 Nop14-like family 3HCDH_N PF02737.13 EGO59406.1 - 3e-28 98.6 0.0 2.3e-27 95.8 0.0 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EGO59406.1 - 2.4e-15 56.6 0.0 4.1e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.14 EGO59406.1 - 0.0016 17.6 0.0 0.0042 16.2 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 EGO59406.1 - 0.0084 16.0 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EGO59406.1 - 0.028 13.8 0.0 0.06 12.7 0.0 1.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EGO59406.1 - 0.029 14.0 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 EGO59406.1 - 0.032 14.6 0.0 0.059 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EGO59406.1 - 0.098 12.0 0.3 6.6 6.1 0.0 2.9 3 1 0 3 3 3 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.11 EGO59408.1 - 1.7e-38 132.2 59.5 8e-37 126.7 39.5 3.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO59408.1 - 2e-14 53.0 33.9 3.8e-08 32.3 12.3 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EGO59408.1 - 4.7e-11 41.6 21.8 7e-11 41.0 15.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ESSS PF10183.4 EGO59408.1 - 0.63 10.4 2.5 3.4 8.1 0.0 3.1 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fungal_trans PF04082.13 EGO59409.1 - 9.6e-16 57.4 0.0 1.5e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO59409.1 - 1.2e-09 37.9 10.4 2.3e-09 37.0 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.24 EGO59410.1 - 1.2e-07 31.2 8.6 2.6e-07 30.2 6.0 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EGO59410.1 - 0.00016 22.0 3.2 0.012 15.9 0.0 3.2 3 0 0 3 3 3 2 SET domain E1_DerP2_DerF2 PF02221.10 EGO59412.1 - 5.7e-28 97.8 0.3 6.8e-28 97.5 0.2 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EGO59412.1 - 0.00022 21.2 0.2 0.0015 18.5 0.1 2.3 1 1 1 2 2 2 1 ML-like domain DUF1091 PF06477.8 EGO59412.1 - 0.1 13.0 0.1 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) Wzt_C PF14524.1 EGO59412.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Wzt C-terminal domain DUF2418 PF10332.4 EGO59413.1 - 4.6e-35 119.8 0.8 7.5e-35 119.1 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Cmyb_C PF09316.5 EGO59413.1 - 0.013 15.1 0.0 0.013 15.1 0.0 2.4 2 0 0 2 2 2 0 C-myb, C-terminal Fumarate_red_D PF02313.12 EGO59413.1 - 0.053 13.4 0.4 0.18 11.7 0.1 1.8 2 0 0 2 2 2 0 Fumarate reductase subunit D Aconitase PF00330.15 EGO59414.1 - 4.4e-184 612.3 0.0 6.6e-184 611.7 0.0 1.3 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGO59414.1 - 8.5e-45 152.0 0.0 1.5e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain F-box PF00646.28 EGO59416.1 - 7.5e-05 22.2 0.1 0.00018 21.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGO59416.1 - 0.019 14.6 0.2 0.046 13.4 0.1 1.7 1 0 0 1 1 1 0 F-box-like IncA PF04156.9 EGO59416.1 - 0.25 10.9 5.3 0.1 12.1 1.4 2.0 2 0 0 2 2 2 0 IncA protein Transglut_core PF01841.14 EGO59417.1 - 1.7e-10 41.0 0.0 3.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 EGO59417.1 - 0.14 11.4 0.0 1.6 7.9 0.0 2.3 1 1 0 1 1 1 0 Transglutaminase-like domain Methyltransf_16 PF10294.4 EGO59418.1 - 4.4e-13 49.0 0.0 2.8e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Dehydrin PF00257.14 EGO59418.1 - 0.00031 21.0 0.0 0.0004 20.7 0.0 1.3 1 0 0 1 1 1 1 Dehydrin YtxH PF12732.2 EGO59418.1 - 0.05 13.9 0.2 0.15 12.4 0.1 1.8 1 0 0 1 1 1 0 YtxH-like protein AMP-binding PF00501.23 EGO59419.1 - 1.2e-82 277.5 0.0 1.8e-82 276.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO59419.1 - 0.043 14.7 0.1 0.12 13.3 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain EF-hand_1 PF00036.27 EGO59420.1 - 6.5e-24 81.3 11.2 4.9e-08 31.7 0.2 4.7 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 EGO59420.1 - 7.6e-23 78.3 3.5 1.5e-06 27.6 0.1 5.1 4 1 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 EGO59420.1 - 8.8e-22 77.0 2.6 4e-13 49.2 0.4 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EGO59420.1 - 7.2e-17 59.8 11.8 2e-05 23.7 0.6 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EGO59420.1 - 8.3e-15 54.1 11.8 6.5e-06 25.6 0.7 4.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EGO59420.1 - 1.9e-08 34.0 6.3 0.0043 16.7 0.1 3.8 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EGO59420.1 - 0.00027 20.8 0.5 0.0037 17.1 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 EGO59420.1 - 0.0025 17.4 0.8 1.1 9.0 0.0 3.3 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.4 EGO59420.1 - 0.0026 17.7 2.1 1.3 9.0 0.1 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.6 EGO59420.1 - 0.021 14.8 0.2 1.2 9.1 0.0 3.0 3 1 0 3 3 3 0 EF hand CDC45 PF02724.9 EGO59421.1 - 2.2e-242 805.5 11.5 1.6e-218 726.7 0.0 3.0 1 1 2 3 3 3 2 CDC45-like protein Vfa1 PF08432.5 EGO59421.1 - 0.0019 18.2 19.8 0.0019 18.2 13.7 1.8 2 0 0 2 2 2 1 AAA-ATPase Vps4-associated protein 1 Nop25 PF09805.4 EGO59421.1 - 0.41 10.7 33.5 0.023 14.7 15.6 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) RNase_H2-Ydr279 PF09468.5 EGO59421.1 - 0.81 8.8 9.5 1.5 7.9 6.6 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF1168 PF06658.7 EGO59421.1 - 2.2 7.7 27.9 5.2 6.5 19.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) CMV_1a PF12467.3 EGO59421.1 - 6.2 7.1 14.7 50 4.1 10.9 1.9 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Methyltransf_23 PF13489.1 EGO59422.1 - 1e-17 64.3 0.0 1.7e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO59422.1 - 6.4e-09 36.3 0.1 1.2e-07 32.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO59422.1 - 2.9e-08 34.0 0.0 5.7e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO59422.1 - 1.1e-07 31.5 0.0 2.4e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO59422.1 - 6.1e-05 23.3 0.0 0.00024 21.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO59422.1 - 0.00016 20.8 0.0 0.0012 17.9 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EGO59422.1 - 0.0003 21.2 0.0 0.002 18.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGO59422.1 - 0.0013 18.7 0.1 0.0029 17.6 0.1 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EGO59422.1 - 0.0037 16.3 0.0 0.0072 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Cupin_8 PF13621.1 EGO59423.1 - 3.4e-32 111.9 0.0 6.3e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EGO59423.1 - 3.1e-10 39.8 0.0 6.5e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 EGO59423.1 - 0.00011 22.3 0.0 0.0037 17.5 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EGO59423.1 - 0.019 14.4 0.1 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 Cupin domain Glycos_transf_4 PF00953.16 EGO59424.1 - 9.6e-32 109.9 11.4 9.6e-32 109.9 7.9 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 4 WD40 PF00400.27 EGO59425.1 - 6.2e-17 60.7 1.2 4e-05 23.3 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat MFS_1 PF07690.11 EGO59426.1 - 8.2e-26 90.5 47.3 9.7e-24 83.7 21.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGO59426.1 - 0.25 11.1 6.8 2.3 8.0 0.2 3.0 3 0 0 3 3 3 0 MFS_1 like family FKBP_C PF00254.23 EGO59429.1 - 2.9e-21 75.3 0.0 3.2e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ThiF PF00899.16 EGO59430.1 - 3e-52 176.0 0.0 7.1e-33 113.3 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EGO59430.1 - 6.7e-39 132.9 0.0 4.3e-38 130.2 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EGO59430.1 - 8.6e-39 130.9 1.8 1.3e-27 95.1 0.2 2.9 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EGO59430.1 - 1.4e-25 88.3 1.4 3e-21 74.5 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site End_beta_barrel PF12195.3 EGO59430.1 - 0.3 10.8 2.5 19 5.1 0.0 2.6 1 1 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase Ribonuc_2-5A PF06479.7 EGO59431.1 - 0.046 13.5 0.9 0.098 12.5 0.6 1.5 1 0 0 1 1 1 0 Ribonuclease 2-5A AKAP95 PF04988.7 EGO59431.1 - 0.084 12.6 0.8 0.17 11.6 0.5 1.5 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) EnY2 PF10163.4 EGO59431.1 - 1.7 8.6 8.3 2.6 8.0 3.8 2.4 1 1 1 2 2 2 0 Transcription factor e(y)2 zf-RING_3 PF14369.1 EGO59432.1 - 1.7 8.6 4.1 24 5.0 0.5 2.3 2 0 0 2 2 2 0 zinc-finger GST_N_2 PF13409.1 EGO59433.1 - 3.3e-22 78.2 0.0 1.4e-21 76.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO59433.1 - 2.5e-16 59.2 0.0 1.2e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO59433.1 - 2.7e-06 27.2 0.0 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGO59433.1 - 5.2e-06 26.5 0.0 0.072 13.3 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGO59433.1 - 0.00011 22.6 0.0 0.00024 21.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tropomyosin_1 PF12718.2 EGO59433.1 - 0.075 12.8 0.3 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF4110 PF13422.1 EGO59436.1 - 0.084 12.7 0.2 0.69 9.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) DUF809 PF05663.6 EGO59436.1 - 0.14 12.0 0.6 0.24 11.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) PAP_assoc PF03828.14 EGO59438.1 - 1.3e-18 66.6 0.2 3.3e-13 49.3 0.0 2.6 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EGO59438.1 - 0.08 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain PAP_central PF04928.12 EGO59438.1 - 0.2 10.4 0.0 11 4.7 0.0 2.3 2 0 0 2 2 2 0 Poly(A) polymerase central domain CDC45 PF02724.9 EGO59438.1 - 0.32 8.9 3.0 0.49 8.3 2.1 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 EGO59439.1 - 1.1e-05 24.0 54.7 1.2e-05 23.9 4.4 2.7 1 1 2 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bud13 PF09736.4 EGO59441.1 - 2.2e-46 157.7 7.9 2.2e-46 157.7 5.5 2.7 2 2 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Zn_clus PF00172.13 EGO59443.1 - 2.1e-06 27.5 10.5 3.4e-06 26.8 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_23 PF13476.1 EGO59443.1 - 0.22 11.8 3.4 0.35 11.1 2.4 1.3 1 0 0 1 1 1 0 AAA domain DHquinase_I PF01487.10 EGO59444.1 - 2.4e-29 102.6 0.0 1.1e-28 100.4 0.0 1.8 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.17 EGO59444.1 - 6.4e-24 84.6 0.0 1.2e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.6 EGO59444.1 - 3.9e-15 55.6 0.0 9.3e-15 54.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EGO59444.1 - 9.6e-14 51.6 0.2 2.4e-13 50.3 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EGO59444.1 - 0.003 17.9 0.2 0.01 16.2 0.1 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 EGO59444.1 - 0.13 12.0 0.1 0.34 10.7 0.1 1.7 1 0 0 1 1 1 0 ThiF family PI3_PI4_kinase PF00454.22 EGO59447.1 - 1.2e-40 139.4 0.0 1.6e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ResIII PF04851.10 EGO59449.1 - 3.7e-22 79.0 0.0 8.3e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGO59449.1 - 3.8e-14 52.2 0.0 9.9e-14 50.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO59449.1 - 2.5e-12 46.6 0.0 6.1e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EGO59449.1 - 0.00049 19.1 0.0 0.00087 18.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Myb_DNA-binding PF00249.26 EGO59450.1 - 1.1e-05 25.3 0.0 2.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain 2_5_RNA_ligase2 PF13563.1 EGO59451.1 - 2.4e-52 176.7 0.2 5e-52 175.6 0.1 1.6 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 EGO59451.1 - 3.3e-22 78.5 0.0 9.4e-22 77.0 0.0 1.8 1 1 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.18 EGO59451.1 - 2e-15 57.4 0.1 3.4e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF504 PF04457.7 EGO59451.1 - 6.8e-12 45.3 0.2 1.4e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF504) PAP_RNA-bind PF04926.10 EGO59451.1 - 6.6e-09 35.4 0.0 1.4e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EGO59451.1 - 0.0046 17.2 0.0 0.015 15.6 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Exo_endo_phos_2 PF14529.1 EGO59451.1 - 0.024 14.2 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase AKAP7_NLS PF10469.4 EGO59451.1 - 0.027 14.1 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain Chitin_synth_2 PF03142.10 EGO59452.1 - 7.7e-254 842.9 1.8 1e-253 842.5 1.2 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EGO59452.1 - 9.5e-169 562.6 0.0 1.3e-168 562.2 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EGO59452.1 - 8.7e-19 67.1 0.0 1.3e-12 47.2 0.0 2.8 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EGO59452.1 - 9.4e-18 63.7 0.5 1.1e-16 60.2 0.2 2.4 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EGO59452.1 - 9.8e-16 58.0 6.1 2.9e-15 56.4 4.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGO59452.1 - 2.9e-15 56.7 0.2 1.8e-11 44.2 0.1 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGO59452.1 - 3e-05 23.7 0.0 0.008 15.8 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_16 PF13191.1 EGO59452.1 - 0.0055 16.7 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO59452.1 - 0.0083 16.2 0.1 0.029 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGO59452.1 - 0.0097 15.4 0.1 0.028 13.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Glyco_transf_21 PF13506.1 EGO59452.1 - 0.011 15.0 0.0 0.03 13.5 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF1622 PF07784.6 EGO59452.1 - 0.041 13.5 0.7 4.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) AAA_23 PF13476.1 EGO59452.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EGO59452.1 - 0.16 11.6 0.2 0.69 9.6 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 EGO59452.1 - 0.28 9.8 0.0 0.67 8.5 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit Chitin_synth_2 PF03142.10 EGO59454.1 - 8.7e-230 763.5 0.1 1.2e-229 763.1 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EGO59454.1 - 2.2e-59 201.2 0.0 5.9e-50 170.0 0.0 2.4 2 1 0 2 2 2 2 Myosin head (motor domain) Cyt-b5 PF00173.23 EGO59454.1 - 1.7e-20 72.5 0.0 8.2e-15 54.3 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EGO59454.1 - 5.2e-17 62.1 3.6 5.2e-17 62.1 2.5 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGO59454.1 - 2.1e-15 57.1 0.0 1.4e-12 47.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 EGO59454.1 - 6.2e-14 51.5 2.3 4.2e-13 48.8 1.4 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_transf_21 PF13506.1 EGO59454.1 - 2.9e-06 26.7 0.0 1.8e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EGO59454.1 - 0.00062 19.4 0.0 0.044 13.4 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Bacillus_HBL PF05791.6 EGO59454.1 - 0.082 12.2 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) BCDHK_Adom3 PF10436.4 EGO59455.1 - 9e-45 152.1 0.0 1.3e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EGO59455.1 - 8.3e-16 57.6 0.0 1.4e-14 53.7 0.0 2.6 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.11 EGO59456.1 - 3.1e-08 34.0 0.8 5.9e-08 33.1 0.2 1.6 2 0 0 2 2 2 1 Peptidase inhibitor I9 DUF663 PF04950.7 EGO59457.1 - 3e-91 305.4 0.0 3e-91 305.4 0.0 2.1 2 1 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EGO59457.1 - 1.3e-28 98.3 0.1 6.1e-27 92.9 0.0 2.7 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA_16 PF13191.1 EGO59457.1 - 2.3e-06 27.7 0.0 5.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGO59457.1 - 1.9e-05 24.8 0.0 5.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EGO59457.1 - 4e-05 23.1 0.5 0.0042 16.5 0.0 2.9 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EGO59457.1 - 0.00033 20.9 0.9 0.0018 18.5 0.0 2.6 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.7 EGO59457.1 - 0.00037 20.1 0.0 0.00085 19.0 0.0 1.7 1 1 0 1 1 1 1 NACHT domain Miro PF08477.8 EGO59457.1 - 0.00046 20.6 2.4 0.00058 20.3 0.0 2.4 2 0 0 2 2 1 1 Miro-like protein AAA_19 PF13245.1 EGO59457.1 - 0.0011 18.6 0.3 0.003 17.2 0.0 1.8 2 0 0 2 2 1 1 Part of AAA domain AAA PF00004.24 EGO59457.1 - 0.0013 18.9 0.1 0.0032 17.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGO59457.1 - 0.0016 18.3 0.1 0.0068 16.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.18 EGO59457.1 - 0.0027 17.6 0.1 0.0098 15.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EGO59457.1 - 0.0028 17.3 0.0 0.0096 15.6 0.0 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EGO59457.1 - 0.0043 17.8 0.0 0.0043 17.8 0.0 4.1 2 1 1 3 3 2 1 AAA domain AAA_33 PF13671.1 EGO59457.1 - 0.0051 16.7 0.2 0.016 15.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_10 PF12846.2 EGO59457.1 - 0.0068 15.8 0.2 0.026 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain PduV-EutP PF10662.4 EGO59457.1 - 0.0092 15.4 0.0 0.041 13.3 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 EGO59457.1 - 0.011 14.5 1.3 0.043 12.6 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 EGO59457.1 - 0.014 14.7 0.0 0.035 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGO59457.1 - 0.031 13.9 0.1 0.031 13.9 0.1 2.1 2 0 0 2 2 2 0 NTPase cobW PF02492.14 EGO59457.1 - 0.033 13.6 0.0 0.083 12.3 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EGO59457.1 - 0.035 14.2 0.0 0.096 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EGO59457.1 - 0.042 14.1 0.0 0.042 14.1 0.0 4.6 4 2 0 4 4 3 0 AAA domain AAA_5 PF07728.9 EGO59457.1 - 0.043 13.5 0.0 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EGO59457.1 - 0.077 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_21 PF13304.1 EGO59457.1 - 1.1 9.1 0.0 1.1 9.1 0.0 3.2 3 1 0 3 3 1 0 AAA domain AAA_11 PF13086.1 EGO59457.1 - 7.7 6.0 12.9 3.1 7.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain Radical_SAM PF04055.16 EGO59458.1 - 7.1e-08 32.8 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EGO59458.1 - 9.7e-05 22.5 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EGO59458.1 - 0.045 13.7 0.1 0.045 13.7 0.1 1.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Radial_spoke PF04712.7 EGO59459.1 - 0.0025 16.6 8.6 0.0069 15.1 0.9 3.0 3 1 0 3 3 3 1 Radial spokehead-like protein Serglycin PF04360.7 EGO59459.1 - 0.063 13.0 0.5 0.16 11.7 0.3 1.7 1 0 0 1 1 1 0 Serglycin Nucleoplasmin PF03066.10 EGO59459.1 - 0.095 12.2 12.9 0.17 11.4 3.3 2.4 2 0 0 2 2 2 0 Nucleoplasmin COG5 PF10392.4 EGO59459.1 - 0.29 11.0 8.6 3.5 7.6 1.0 3.1 2 2 0 2 2 2 0 Golgi transport complex subunit 5 Syntaxin PF00804.20 EGO59459.1 - 0.65 10.1 7.0 1.6 8.9 0.5 2.9 3 0 0 3 3 3 0 Syntaxin Trypan_PARP PF05887.6 EGO59459.1 - 4.3 7.1 20.8 1.4 8.7 2.0 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Ribosomal_60s PF00428.14 EGO59459.1 - 9.9 6.6 18.3 1.4 9.3 1.1 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF1681 PF07933.9 EGO59460.1 - 1.7e-59 199.9 0.0 2.5e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SBDS_C PF09377.5 EGO59460.1 - 0.073 12.7 0.1 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 SBDS protein C-terminal domain Methyltransf_33 PF10017.4 EGO59462.1 - 2.1e-28 98.7 0.0 3.6e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EGO59462.1 - 1.6e-20 73.6 2.2 1.4e-12 47.4 0.2 2.5 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EGO59462.1 - 1.1e-06 29.0 0.8 3e-06 27.5 0.6 1.8 1 0 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.1 EGO59462.1 - 0.039 14.3 0.0 0.088 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GFA PF04828.9 EGO59463.1 - 7.8e-12 44.9 17.7 7.1e-09 35.5 0.3 2.7 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme CENP-U PF13097.1 EGO59464.1 - 1.3 8.9 6.8 1.6 8.6 3.0 2.3 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit Acetyltransf_1 PF00583.19 EGO59465.1 - 0.016 15.1 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Pho86 PF11124.3 EGO59465.1 - 0.017 14.1 0.1 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 DUF4231 PF14015.1 EGO59465.1 - 0.031 14.2 0.6 0.065 13.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) PfkB PF00294.19 EGO59466.1 - 2.3e-54 184.6 1.0 2.7e-54 184.3 0.7 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF3455 PF11937.3 EGO59466.1 - 0.067 13.1 0.0 0.59 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3455) Svf1 PF08622.5 EGO59468.1 - 2.8e-133 443.9 0.0 3.3e-133 443.6 0.0 1.1 1 0 0 1 1 1 1 Svf1-like Ribosomal_L11_N PF03946.9 EGO59469.1 - 1.1e-26 92.0 0.1 1.7e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EGO59469.1 - 5.9e-24 83.9 0.2 2.1e-23 82.2 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Pkinase PF00069.20 EGO59470.1 - 1.2e-58 198.2 0.0 4.5e-58 196.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO59470.1 - 6.8e-22 77.7 0.0 1.1e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO59470.1 - 0.0021 17.8 0.3 0.016 14.9 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Cpn10 PF00166.16 EGO59471.1 - 1.5e-28 98.5 0.0 1.7e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Glyco_hydro_61 PF03443.9 EGO59472.1 - 1.1e-41 143.0 0.5 3.7e-41 141.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 SNF2_N PF00176.18 EGO59473.1 - 1.8e-71 240.3 0.3 2.7e-71 239.7 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EGO59473.1 - 1.4e-17 63.5 0.0 3e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.1 EGO59473.1 - 4.1e-11 42.5 10.4 4.1e-11 42.5 7.2 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGO59473.1 - 3.9e-10 39.2 12.3 1.9e-09 37.0 6.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 EGO59473.1 - 1.4e-09 37.7 0.0 4.4e-09 36.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EGO59473.1 - 1.7e-09 37.5 16.5 3.5e-09 36.5 9.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO59473.1 - 4.1e-08 32.7 14.7 6.7e-08 32.0 8.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO59473.1 - 7.2e-07 28.8 9.7 7.2e-07 28.8 6.7 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGO59473.1 - 2e-06 27.5 12.2 4.4e-06 26.4 8.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGO59473.1 - 3.7e-06 26.9 2.4 1.3e-05 25.2 1.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EGO59473.1 - 0.0011 18.6 4.3 0.003 17.3 3.0 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EGO59473.1 - 0.0017 17.9 11.5 0.0056 16.3 8.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-P11 PF03854.9 EGO59473.1 - 0.0021 17.5 10.4 0.0078 15.6 1.5 2.7 2 1 1 3 3 3 2 P-11 zinc finger zf-Apc11 PF12861.2 EGO59473.1 - 0.0042 16.8 3.5 0.0099 15.6 2.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EGO59473.1 - 0.0091 15.5 9.1 0.03 13.8 6.3 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EGO59473.1 - 0.025 14.1 8.0 0.069 12.7 5.5 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EGO59473.1 - 0.4 10.2 7.4 5.7 6.5 5.1 2.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Activator_LAG-3 PF11498.3 EGO59475.1 - 0.0062 15.3 22.7 0.0097 14.6 15.7 1.4 1 0 0 1 1 1 1 Transcriptional activator LAG-3 DUF605 PF04652.11 EGO59475.1 - 0.15 11.4 40.1 0.17 11.2 27.8 1.0 1 0 0 1 1 1 0 Vta1 like Menin PF05053.8 EGO59476.1 - 0.37 8.8 2.3 0.52 8.4 1.6 1.2 1 0 0 1 1 1 0 Menin DUF3482 PF11981.3 EGO59477.1 - 0.017 14.3 3.1 0.029 13.6 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) DUF4584 PF15223.1 EGO59477.1 - 0.069 12.4 3.7 0.082 12.1 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4584) Treacle PF03546.9 EGO59477.1 - 0.097 11.4 3.8 0.11 11.2 2.6 1.0 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle Pal1 PF08316.6 EGO59477.1 - 0.15 12.4 0.4 0.39 11.1 0.0 1.8 1 1 1 2 2 2 0 Pal1 cell morphology protein DUF533 PF04391.7 EGO59477.1 - 9.7 5.5 6.5 1.4 8.2 1.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF533) DUF3659 PF12396.3 EGO59478.1 - 9.5e-17 60.4 4.9 4.1e-12 45.5 1.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) DUF3659 PF12396.3 EGO59480.1 - 1.8e-109 357.4 44.5 9.2e-24 82.9 2.1 5.5 5 0 0 5 5 5 5 Protein of unknown function (DUF3659) TPP_enzyme_N PF02776.13 EGO59481.1 - 3.2e-58 196.0 0.1 1.7e-57 193.6 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGO59481.1 - 6.9e-50 168.5 0.1 1.4e-48 164.3 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGO59481.1 - 7.1e-36 122.9 4.9 9.3e-36 122.6 0.2 2.9 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain DUF680 PF05079.7 EGO59482.1 - 0.088 13.3 0.3 0.088 13.3 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF680) Csm1 PF12539.3 EGO59483.1 - 1.9e-27 95.5 0.1 4.6e-27 94.3 0.1 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Spc7 PF08317.6 EGO59483.1 - 0.0032 16.2 10.9 0.0032 16.2 7.5 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein NPV_P10 PF05531.7 EGO59483.1 - 0.025 14.8 0.7 0.025 14.8 0.5 2.7 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EGO59483.1 - 8.7 5.8 28.3 0.12 11.9 5.1 3.4 3 1 1 4 4 4 0 IncA protein MFS_1 PF07690.11 EGO59484.1 - 3.3e-17 62.2 39.9 8.6e-17 60.8 10.2 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EGO59484.1 - 4.9e-10 39.0 3.9 4.9e-10 39.0 2.7 2.0 2 0 0 2 2 2 1 Nodulin-like Serinc PF03348.10 EGO59486.1 - 2.8e-177 589.7 4.1 3.2e-177 589.5 2.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) NPR3 PF03666.8 EGO59486.1 - 0.2 10.1 0.0 0.3 9.5 0.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cys_Met_Meta_PP PF01053.15 EGO59487.1 - 2.7e-138 460.4 0.0 3.3e-138 460.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EGO59487.1 - 5.9e-07 28.8 0.0 1.9e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EGO59487.1 - 1.9e-06 26.8 0.0 4.6e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGO59487.1 - 2.3e-06 26.8 0.0 4.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 EGO59487.1 - 4.6e-06 25.1 0.1 1.1e-05 23.8 0.1 1.5 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 EGO59487.1 - 0.0052 15.5 0.1 0.012 14.3 0.1 1.5 1 1 0 1 1 1 1 Glycine cleavage system P-protein AAA PF00004.24 EGO59488.1 - 3.2e-37 127.6 0.0 5.4e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGO59488.1 - 9.9e-06 25.4 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO59488.1 - 1.1e-05 25.4 0.1 6.1e-05 23.0 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EGO59488.1 - 2.7e-05 23.9 0.1 0.00024 20.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EGO59488.1 - 2.8e-05 23.2 0.0 5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGO59488.1 - 3e-05 24.1 0.1 0.00041 20.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO59488.1 - 5.3e-05 24.0 0.1 0.0002 22.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EGO59488.1 - 0.00019 21.3 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EGO59488.1 - 0.00094 18.6 0.1 0.0021 17.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EGO59488.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGO59488.1 - 0.0016 17.6 0.1 0.0032 16.6 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EGO59488.1 - 0.0021 17.1 0.0 0.0047 16.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EGO59488.1 - 0.0026 17.4 0.4 0.0099 15.6 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EGO59488.1 - 0.0033 17.1 0.0 0.015 14.9 0.0 2.0 1 1 1 2 2 2 1 NACHT domain RNA_helicase PF00910.17 EGO59488.1 - 0.006 16.7 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Sigma54_activ_2 PF14532.1 EGO59488.1 - 0.0077 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EGO59488.1 - 0.014 14.8 0.3 0.089 12.1 0.1 2.1 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EGO59488.1 - 0.015 14.7 0.0 0.038 13.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 EGO59488.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGO59488.1 - 0.023 14.6 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EGO59488.1 - 0.034 13.0 0.0 0.057 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 EGO59488.1 - 0.039 14.2 0.1 0.1 12.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.8 EGO59488.1 - 0.042 12.5 0.2 0.13 10.9 0.0 1.8 2 0 0 2 2 2 0 TIP49 C-terminus Oxidored_nitro PF00148.14 EGO59488.1 - 0.046 12.3 0.0 0.57 8.7 0.0 2.0 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase KaiC PF06745.8 EGO59488.1 - 0.047 12.8 0.0 0.11 11.5 0.0 1.6 1 1 0 1 1 1 0 KaiC Arch_ATPase PF01637.13 EGO59488.1 - 0.048 13.3 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase DUF815 PF05673.8 EGO59488.1 - 0.055 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 EGO59488.1 - 0.072 13.3 0.0 0.17 12.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.12 EGO59488.1 - 0.092 11.6 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 EGO59488.1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein Viral_helicase1 PF01443.13 EGO59488.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 EGO59488.1 - 0.17 10.5 0.0 0.25 9.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Clat_adaptor_s PF01217.15 EGO59489.1 - 4.8e-57 191.6 2.0 5.3e-57 191.5 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain U3_snoRNA_assoc PF08297.6 EGO59490.1 - 0.0072 16.5 0.5 0.027 14.6 0.3 2.0 1 0 0 1 1 1 1 U3 snoRNA associated zf-CCHC_2 PF13696.1 EGO59490.1 - 0.16 11.5 8.8 0.029 13.8 0.7 2.5 2 0 0 2 2 2 0 Zinc knuckle PHD PF00628.24 EGO59490.1 - 0.44 10.2 2.6 0.9 9.2 1.8 1.5 1 0 0 1 1 1 0 PHD-finger Ist1 PF03398.9 EGO59491.1 - 2e-66 222.5 2.1 2.5e-66 222.1 1.5 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway TFIID-18kDa PF02269.11 EGO59493.1 - 8.9e-28 95.9 0.2 5.3e-27 93.4 0.0 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit LCM PF04072.9 EGO59494.1 - 8.2e-24 84.1 0.1 7.1e-23 81.1 0.0 2.3 2 1 0 2 2 2 1 Leucine carboxyl methyltransferase F-box-like PF12937.2 EGO59498.1 - 5.3e-09 35.6 0.1 1.1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO59498.1 - 5.4e-06 25.9 0.0 1.4e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain UIM PF02809.15 EGO59498.1 - 0.00019 20.7 16.9 0.021 14.3 1.5 3.4 3 0 0 3 3 3 2 Ubiquitin interaction motif HypA PF01155.14 EGO59499.1 - 0.042 13.5 1.4 0.042 13.5 0.9 3.3 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family DUF3597 PF12200.3 EGO59499.1 - 0.31 11.4 2.7 0.63 10.4 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Helicase_C_3 PF13625.1 EGO59500.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Helicase conserved C-terminal domain CDC27 PF09507.5 EGO59501.1 - 3.8e-110 369.0 27.7 4.8e-110 368.7 19.2 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 CytochromB561_N PF09786.4 EGO59501.1 - 5.9 5.2 7.1 9.1 4.5 4.9 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal PigN PF04987.9 EGO59502.1 - 4.4e-171 569.4 26.7 5.4e-171 569.1 18.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EGO59502.1 - 4.2e-10 39.5 0.3 7.9e-08 32.0 0.0 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGO59502.1 - 6.9e-09 35.3 0.1 1.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Fungal_trans PF04082.13 EGO59503.1 - 9.2e-37 126.3 0.0 4.5e-36 124.0 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO59503.1 - 0.0012 18.6 1.4 0.0024 17.7 1.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gag_spuma PF03276.9 EGO59503.1 - 0.13 10.5 57.5 0.079 11.2 17.6 2.7 2 0 0 2 2 2 0 Spumavirus gag protein Ycf1 PF05758.7 EGO59503.1 - 0.89 7.1 19.1 0.12 10.0 6.3 2.1 2 0 0 2 2 2 0 Ycf1 RAB3GAP2_N PF14655.1 EGO59503.1 - 1.4 7.8 19.4 0.082 11.8 3.0 2.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Zip PF02535.17 EGO59503.1 - 1.9 7.3 10.1 0.26 10.2 1.1 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter Spore_coat_CotO PF14153.1 EGO59503.1 - 3.4 7.0 32.3 1.4 8.2 11.0 2.5 2 0 0 2 2 2 0 Spore coat protein CotO Hid1 PF12722.2 EGO59503.1 - 4.5 4.8 31.9 0.16 9.6 5.9 2.3 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein BRO1 PF03097.13 EGO59504.1 - 1.6e-136 454.9 2.6 1.6e-136 454.9 1.8 2.1 3 1 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EGO59504.1 - 5.5e-91 304.6 21.7 5.5e-91 304.6 15.1 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV COG2 PF06148.6 EGO59504.1 - 1.5 8.7 12.3 0.092 12.6 1.8 3.5 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Carn_acyltransf PF00755.15 EGO59505.1 - 1.8e-175 584.4 0.0 2e-175 584.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SWIRM PF04433.12 EGO59506.1 - 1.8e-33 114.5 0.1 3.4e-33 113.6 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EGO59506.1 - 6e-08 32.6 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGO59506.1 - 1.5e-05 25.0 0.5 3.3e-05 23.8 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EGO59506.1 - 0.4 10.2 5.3 0.85 9.2 3.7 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type ETF PF01012.16 EGO59507.1 - 1.9e-41 141.5 1.6 3.2e-41 140.7 1.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EGO59507.1 - 1.2e-36 124.1 0.2 2.9e-36 122.9 0.2 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain PfkB PF00294.19 EGO59509.1 - 9.2e-18 64.3 0.0 1.6e-09 37.3 0.1 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase DUF4611 PF15387.1 EGO59509.1 - 0.11 12.6 1.2 0.51 10.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) MCM PF00493.18 EGO59510.1 - 5.9e-131 436.1 0.2 8.6e-131 435.6 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGO59510.1 - 4.9e-14 52.8 0.0 4.2e-13 49.8 0.0 2.5 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGO59510.1 - 2.6e-07 29.9 0.0 3.5e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGO59510.1 - 0.0025 17.4 0.0 0.0078 15.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGO59510.1 - 0.01 15.3 0.0 0.027 13.9 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain TFIIA PF03153.8 EGO59510.1 - 0.021 14.7 27.4 0.23 11.3 14.8 2.2 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Aminotran_3 PF00202.16 EGO59511.1 - 5.9e-85 285.0 0.0 7e-85 284.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EGO59511.1 - 0.00012 21.1 0.0 0.00033 19.7 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Exo70 PF03081.10 EGO59512.1 - 3.6e-71 239.8 0.0 8.9e-71 238.6 0.0 1.6 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Apolipoprotein PF01442.13 EGO59512.1 - 0.13 11.7 6.1 0.49 9.8 0.1 3.4 4 0 0 4 4 4 0 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.7 EGO59512.1 - 0.41 10.9 3.0 21 5.4 0.0 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Gp-FAR-1 PF05823.7 EGO59518.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FAA_hydrolase PF01557.13 EGO59519.1 - 3.9e-52 176.8 0.0 5.5e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MutL_C PF08676.6 EGO59521.1 - 3.7e-22 78.4 0.1 1.2e-21 76.8 0.0 1.9 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EGO59521.1 - 4e-18 65.0 0.0 1e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EGO59521.1 - 1.1e-14 54.2 0.2 1.4e-13 50.7 0.1 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGO59521.1 - 1.2e-11 44.2 0.0 3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PGAP1 PF07819.8 EGO59523.1 - 6e-88 294.2 0.0 1.2e-87 293.2 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGO59523.1 - 3e-06 27.0 0.0 6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO59523.1 - 3.7e-05 23.7 0.1 7.1e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO59523.1 - 0.0045 16.5 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 EGO59523.1 - 0.026 13.8 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) COesterase PF00135.23 EGO59523.1 - 0.075 11.7 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family Lipase_3 PF01764.20 EGO59523.1 - 0.088 12.4 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PolyA_pol PF01743.15 EGO59524.1 - 1e-26 93.5 0.3 2.7e-26 92.2 0.2 1.8 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EGO59524.1 - 5.9e-07 28.9 0.1 1.5e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EGO59524.1 - 0.00017 21.4 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative Sec7 PF01369.15 EGO59525.1 - 1.6e-59 200.8 0.0 2.6e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EGO59525.1 - 1.5e-18 66.8 0.2 5.6e-11 42.1 0.0 3.4 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Anp1 PF03452.9 EGO59526.1 - 1.5e-123 411.2 0.5 2.5e-123 410.5 0.0 1.5 2 0 0 2 2 2 1 Anp1 DUF2146 PF10220.4 EGO59526.1 - 0.052 11.5 3.2 0.066 11.1 2.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Totivirus_coat PF05518.6 EGO59526.1 - 0.5 8.1 3.0 0.71 7.6 2.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein RNase_PH PF01138.16 EGO59528.1 - 1.4e-25 90.1 0.0 2.3e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 GDA1_CD39 PF01150.12 EGO59530.1 - 1.1e-101 340.4 0.0 1.5e-101 340.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF775 PF05603.7 EGO59531.1 - 1.1e-52 178.4 0.0 1.3e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 EGO59532.1 - 2.1e-06 27.4 0.0 4.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain PAXNEB PF05625.6 EGO59533.1 - 5.6e-109 364.3 0.0 6.1e-109 364.1 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 EGO59534.1 - 2.4e-15 56.0 0.0 4.6e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain B PF02216.11 EGO59534.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 B domain zf-C3HC4_3 PF13920.1 EGO59535.1 - 2.6e-06 26.9 16.6 4.5e-06 26.2 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) KAR9 PF08580.5 EGO59535.1 - 0.038 12.2 1.6 0.06 11.6 1.1 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 ATP-synt_D PF01813.12 EGO59536.1 - 1.6e-62 210.5 4.2 2.2e-62 210.0 2.9 1.2 1 0 0 1 1 1 1 ATP synthase subunit D YdfA_immunity PF12127.3 EGO59536.1 - 0.78 8.5 8.7 14 4.4 0.0 2.3 2 0 0 2 2 2 0 SigmaW regulon antibacterial Viral_P18 PF04521.8 EGO59536.1 - 5.1 6.5 6.8 4 6.9 0.1 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein TPR_12 PF13424.1 EGO59537.1 - 2.3e-11 43.4 0.3 0.48 10.3 0.0 7.5 6 1 1 7 7 7 2 Tetratricopeptide repeat Suf PF05843.9 EGO59537.1 - 1e-09 38.5 9.4 0.016 14.9 0.0 6.0 3 2 3 6 6 6 2 Suppressor of forked protein (Suf) TPR_15 PF13429.1 EGO59537.1 - 4.5e-08 32.4 10.3 1.5e-05 24.2 0.6 4.5 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGO59537.1 - 7.8e-07 29.1 18.1 5.8 7.8 0.0 10.5 9 3 3 12 12 12 2 Tetratricopeptide repeat NRDE-2 PF08424.5 EGO59537.1 - 3.1e-05 23.0 11.6 0.1 11.4 0.1 5.9 2 2 4 6 6 6 2 NRDE-2, necessary for RNA interference TPR_11 PF13414.1 EGO59537.1 - 0.0002 20.9 4.2 3.9 7.2 0.0 6.2 7 0 0 7 7 7 1 TPR repeat Mad3_BUB1_I PF08311.7 EGO59537.1 - 0.0022 17.8 11.9 1.2 8.9 0.1 6.5 7 1 0 7 7 7 1 Mad3/BUB1 homology region 1 TPR_2 PF07719.12 EGO59537.1 - 0.0027 17.4 15.2 4.3 7.4 0.0 6.9 9 0 0 9 9 7 1 Tetratricopeptide repeat RPN7 PF10602.4 EGO59537.1 - 0.0037 16.6 1.2 0.018 14.3 0.2 2.7 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_8 PF13181.1 EGO59537.1 - 0.071 12.9 6.1 1.2 9.1 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 EGO59537.1 - 0.41 10.9 3.6 10 6.5 0.0 5.0 7 0 0 7 7 6 0 Tetratricopeptide repeat HAT PF02184.11 EGO59537.1 - 0.95 9.2 18.0 4.4 7.1 1.1 7.5 7 1 0 7 7 7 0 HAT (Half-A-TPR) repeat AflR PF08493.5 EGO59538.1 - 0.14 11.2 5.3 0.15 11.1 3.7 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein DUF3129 PF11327.3 EGO59539.1 - 1.2e-57 194.6 10.0 1.2e-57 194.6 6.9 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3129) DivIVA PF05103.8 EGO59540.1 - 0.064 13.3 0.8 0.16 11.9 0.3 1.7 2 0 0 2 2 2 0 DivIVA protein zf-RING_5 PF14634.1 EGO59541.1 - 0.0011 18.6 6.2 0.016 14.9 4.3 2.3 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGO59541.1 - 0.006 16.2 5.8 0.016 14.8 4.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO59541.1 - 0.011 15.5 4.5 0.024 14.4 3.1 1.7 1 0 0 1 1 1 0 Ring finger domain zinc-ribbons_6 PF07191.7 EGO59541.1 - 0.024 14.4 4.9 1.3 8.8 0.9 2.2 2 0 0 2 2 2 0 zinc-ribbons Rad50_zn_hook PF04423.9 EGO59541.1 - 0.056 12.9 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-Di19 PF05605.7 EGO59541.1 - 0.061 13.4 0.6 0.18 11.9 0.5 1.8 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4 PF00097.20 EGO59541.1 - 0.07 12.7 2.8 0.13 11.9 1.9 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 EGO59541.1 - 0.11 12.1 1.9 0.21 11.2 1.3 1.5 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_4 PF14570.1 EGO59541.1 - 0.14 11.7 1.0 0.34 10.5 0.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 EGO59541.1 - 0.31 11.1 6.7 0.091 12.7 2.4 1.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 EGO59541.1 - 0.54 10.1 2.8 0.67 9.8 1.9 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.1 EGO59541.1 - 0.64 9.9 5.4 0.15 11.9 1.1 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.2 EGO59541.1 - 1.1 9.1 5.8 14 5.6 4.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon ThiF PF00899.16 EGO59542.1 - 4.6e-09 36.2 0.0 1.5e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 ThiF family Disulph_isomer PF06491.6 EGO59543.1 - 0.063 13.1 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Disulphide isomerase Fungal_trans PF04082.13 EGO59545.1 - 9.7e-29 100.0 0.0 1.6e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO59545.1 - 3.3e-07 30.0 12.6 5.8e-07 29.3 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BatA PF07584.6 EGO59545.1 - 2.5 8.3 5.5 72 3.6 0.0 4.0 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal adh_short PF00106.20 EGO59546.1 - 2.3e-33 115.4 0.1 3.5e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO59546.1 - 8.8e-16 58.3 0.0 1.1e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO59546.1 - 7.5e-13 48.5 0.0 1.2e-12 47.9 0.0 1.3 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EGO59546.1 - 0.034 13.9 0.3 0.083 12.6 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EGO59546.1 - 0.061 12.2 0.1 0.12 11.2 0.1 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Flagellar_rod PF05149.7 EGO59546.1 - 0.18 10.9 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 Paraflagellar rod protein PEMT PF04191.8 EGO59547.1 - 4.7e-57 190.6 9.8 2.8e-36 123.8 1.4 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase eIF3g PF12353.3 EGO59548.1 - 2.7e-44 150.1 1.2 4.4e-44 149.4 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EGO59548.1 - 2.9e-16 58.8 0.1 6.1e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO59548.1 - 3.1e-13 49.4 0.1 6.7e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO59548.1 - 1.5e-07 31.1 0.3 3.5e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2782 PF11191.3 EGO59548.1 - 3.8 7.5 6.2 0.16 11.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) DAO PF01266.19 EGO59550.1 - 2.8e-54 184.4 0.8 3.6e-54 184.0 0.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO59550.1 - 1.1e-05 25.2 0.3 2.8e-05 24.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGO59550.1 - 0.0002 21.4 0.2 0.0039 17.2 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 EGO59550.1 - 0.0063 14.7 0.0 0.63 8.1 0.0 2.4 3 0 0 3 3 3 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.1 EGO59550.1 - 0.088 12.5 0.1 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Syndecan PF01034.15 EGO59550.1 - 0.36 10.5 1.3 0.81 9.3 0.1 2.0 2 0 0 2 2 2 0 Syndecan domain DUF2046 PF09755.4 EGO59551.1 - 0.0001 21.2 0.2 0.0001 21.2 0.2 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) CENP-F_N PF10481.4 EGO59551.1 - 0.0098 15.2 1.3 1 8.7 0.2 2.4 2 0 0 2 2 2 2 Cenp-F N-terminal domain Spc24 PF08286.6 EGO59551.1 - 0.091 12.4 2.3 3 7.5 0.0 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Pox_A_type_inc PF04508.7 EGO59551.1 - 0.15 11.8 8.6 3.2 7.7 0.4 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat IncA PF04156.9 EGO59551.1 - 0.32 10.5 3.9 1.6 8.3 1.0 2.2 2 0 0 2 2 2 0 IncA protein DUF2415 PF10313.4 EGO59552.1 - 1.5e-15 56.5 0.0 5.5e-15 54.7 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Kelch_6 PF13964.1 EGO59552.1 - 0.011 15.8 0.0 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 Kelch motif WD40 PF00400.27 EGO59552.1 - 0.016 15.0 0.6 27 4.8 0.0 4.7 5 0 0 5 5 5 0 WD domain, G-beta repeat HSP70 PF00012.15 EGO59553.1 - 1.1e-267 888.8 15.2 1.3e-267 888.6 10.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGO59553.1 - 7.4e-15 54.3 5.0 3.6e-13 48.8 0.9 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EGO59553.1 - 7.5e-06 25.7 0.2 6.8e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EGO59553.1 - 0.0021 17.8 6.2 5 6.9 1.0 4.6 1 1 1 2 2 2 1 Cell division protein FtsA StbA PF06406.6 EGO59553.1 - 0.0056 15.6 3.0 0.084 11.8 0.0 3.1 3 1 1 4 4 4 1 StbA protein DUF4363 PF14276.1 EGO59553.1 - 0.14 11.8 4.4 0.29 10.8 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Hydantoinase_A PF01968.13 EGO59553.1 - 1.6 7.7 8.9 1.3 8.0 0.0 3.6 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase PPR_2 PF13041.1 EGO59555.1 - 1.3e-21 76.3 2.7 1.1e-05 25.3 0.0 7.6 5 1 3 8 8 8 4 PPR repeat family PPR PF01535.15 EGO59555.1 - 3e-16 58.1 6.1 0.0038 17.0 0.0 8.5 8 0 0 8 8 8 4 PPR repeat PPR_3 PF13812.1 EGO59555.1 - 1.3e-12 46.8 14.1 0.1 12.9 0.0 10.4 14 0 0 14 14 14 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 EGO59555.1 - 1.1e-07 31.1 0.0 0.0065 15.9 0.0 5.0 5 0 0 5 5 5 2 PPR repeat TPR_14 PF13428.1 EGO59555.1 - 0.00051 20.4 10.6 0.4 11.4 0.0 7.5 7 2 1 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO59555.1 - 0.034 14.8 8.0 2.8 8.7 0.2 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat FSH1 PF03959.8 EGO59556.1 - 1.8e-29 102.7 0.0 1.3e-22 80.3 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EGO59556.1 - 5.1e-06 26.0 0.0 2e-05 24.1 0.0 2.0 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGO59556.1 - 9.2e-06 25.6 0.0 1.2e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 EGO59556.1 - 0.017 14.0 0.0 0.4 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Syja_N PF02383.13 EGO59559.1 - 7.9e-91 304.1 0.0 1.6e-90 303.1 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain DUF2454 PF10521.4 EGO59560.1 - 3.7e-78 262.4 0.3 7e-78 261.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) GalKase_gal_bdg PF10509.4 EGO59561.1 - 1.3e-22 78.8 0.0 2.5e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EGO59561.1 - 2.6e-14 53.0 1.6 2.6e-14 53.0 1.1 2.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGO59561.1 - 2e-13 50.3 0.0 5.7e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r4_2 PF08281.7 EGO59561.1 - 0.082 12.3 0.1 0.19 11.1 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 FANCL_C PF11793.3 EGO59562.1 - 0.00015 21.6 8.2 0.00026 20.8 5.7 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 EGO59562.1 - 0.00028 20.8 11.6 0.00044 20.2 8.0 1.3 1 0 0 1 1 1 1 RING-variant domain CopD PF05425.8 EGO59562.1 - 0.0016 18.6 2.0 0.59 10.3 0.3 2.3 2 0 0 2 2 2 2 Copper resistance protein D zf-UDP PF14569.1 EGO59562.1 - 0.077 12.7 5.3 0.16 11.7 2.5 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_4 PF14570.1 EGO59562.1 - 0.71 9.5 10.9 1.9 8.1 7.5 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EGO59562.1 - 1.5 8.5 9.1 2.6 7.8 6.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 EGO59563.1 - 2.4e-21 75.1 7.1 2.6e-17 62.2 1.8 2.5 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGO59563.1 - 1.1e-18 65.9 4.5 3.8e-08 32.6 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGO59563.1 - 6.2e-16 56.9 6.6 1.8e-05 24.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGO59563.1 - 1.3e-09 38.4 18.0 2.3e-07 31.3 2.2 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGO59563.1 - 1.7e-08 34.0 3.1 0.014 15.5 0.1 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO59563.1 - 3.4e-08 33.3 5.4 0.0017 18.2 1.5 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGO59563.1 - 4.7e-08 32.2 0.2 0.033 13.9 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGO59563.1 - 2.4e-06 26.9 5.7 0.034 13.9 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGO59563.1 - 4.6e-06 26.7 12.0 0.027 15.1 2.0 4.2 3 1 2 5 5 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGO59563.1 - 3e-05 24.2 6.1 0.0015 18.8 0.1 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat BTAD PF03704.12 EGO59563.1 - 0.00072 19.8 2.1 0.042 14.1 1.2 2.5 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_9 PF13371.1 EGO59563.1 - 0.0025 17.6 2.3 0.023 14.5 1.3 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat XPC-binding PF09280.6 EGO59563.1 - 0.0035 16.7 4.5 0.0051 16.2 2.4 1.8 2 0 0 2 2 2 1 XPC-binding domain SR-25 PF10500.4 EGO59563.1 - 0.0045 16.5 3.3 0.0065 15.9 2.3 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TPR_6 PF13174.1 EGO59563.1 - 0.14 12.6 10.2 0.75 10.3 0.5 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGO59563.1 - 0.21 11.5 6.4 4.2 7.4 1.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RAP1 PF07218.6 EGO59563.1 - 1.6 6.7 4.3 2 6.3 3.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MIT PF04212.13 EGO59563.1 - 5.3 6.9 7.6 21 5.0 0.0 3.2 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain GATase_5 PF13507.1 EGO59564.1 - 1.2e-98 329.1 0.0 2.1e-98 328.3 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EGO59564.1 - 4.3e-45 153.4 0.8 2.2e-23 82.9 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EGO59564.1 - 3.3e-25 88.1 0.2 1.6e-24 85.9 0.0 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain MRP-L28 PF09812.4 EGO59565.1 - 6.5e-07 29.2 0.2 6.5e-07 29.2 0.1 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L28 Ras PF00071.17 EGO59566.1 - 3.1e-50 169.7 0.0 3.6e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO59566.1 - 2.1e-16 60.4 0.0 3.8e-16 59.6 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGO59566.1 - 1.9e-06 27.2 0.0 2.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGO59566.1 - 0.0065 15.7 0.0 0.0082 15.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EGO59566.1 - 0.025 14.0 0.2 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EGO59566.1 - 0.074 12.1 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_21 PF13304.1 EGO59566.1 - 0.093 12.6 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain NST1 PF13945.1 EGO59568.1 - 1.4e-57 194.8 10.2 1.4e-57 194.8 7.1 5.1 2 2 3 5 5 5 1 Salt tolerance down-regulator DUF3552 PF12072.3 EGO59569.1 - 0.01 15.0 1.5 0.018 14.2 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1049 PF06305.6 EGO59569.1 - 0.092 12.2 0.1 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) CAF-1_p150 PF11600.3 EGO59571.1 - 0.0047 16.3 26.8 0.0052 16.1 18.6 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Nop14 PF04147.7 EGO59571.1 - 0.017 13.0 11.9 0.014 13.3 8.3 1.0 1 0 0 1 1 1 0 Nop14-like family STOP PF05217.7 EGO59571.1 - 0.19 11.4 4.7 0.22 11.2 3.3 1.1 1 0 0 1 1 1 0 STOP protein RR_TM4-6 PF06459.7 EGO59571.1 - 0.23 11.3 9.0 0.23 11.3 6.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.6 EGO59571.1 - 1.1 8.8 21.0 1.3 8.6 14.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 EGO59571.1 - 1.8 7.7 7.8 1.9 7.5 5.4 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) PRKCSH-like PF12999.2 EGO59571.1 - 2.3 7.7 8.0 3 7.3 5.6 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like MAP7 PF05672.6 EGO59571.1 - 2.6 7.4 34.1 3.4 7.0 23.6 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family FYVE PF01363.16 EGO59571.1 - 4.3 7.3 12.0 7.6 6.5 8.3 1.7 1 1 0 1 1 1 0 FYVE zinc finger DUF4407 PF14362.1 EGO59571.1 - 4.6 6.1 9.1 5.2 5.9 6.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DNA_pol3_a_NII PF11490.3 EGO59571.1 - 6.7 6.3 18.2 0.11 12.1 6.3 2.0 1 1 1 2 2 2 0 DNA polymerase III polC-type N-terminus II CDC45 PF02724.9 EGO59571.1 - 7.5 4.4 9.8 7.2 4.5 6.8 1.0 1 0 0 1 1 1 0 CDC45-like protein PUA PF01472.15 EGO59573.1 - 1.6e-12 46.9 0.1 8.4e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 PUA domain Inhibitor_I78 PF11720.3 EGO59574.1 - 2.5e-13 49.5 0.0 3.1e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EGO59574.1 - 0.00017 21.6 0.0 0.00026 21.0 0.0 1.3 1 0 0 1 1 1 1 Potato inhibitor I family DUF1772 PF08592.6 EGO59576.1 - 0.0041 16.8 1.6 0.011 15.5 0.6 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF1772) PPR_2 PF13041.1 EGO59578.1 - 2.8e-49 164.8 8.3 3.7e-11 42.8 0.0 13.9 11 2 4 15 15 15 11 PPR repeat family PPR PF01535.15 EGO59578.1 - 8.7e-27 91.2 26.5 8.1e-05 22.3 0.2 13.9 16 0 0 16 16 16 6 PPR repeat PPR_1 PF12854.2 EGO59578.1 - 6.6e-22 76.6 4.8 1.4e-08 34.0 0.0 10.6 11 0 0 11 11 11 4 PPR repeat PPR_3 PF13812.1 EGO59578.1 - 1.4e-21 74.8 22.0 0.00021 21.3 0.0 14.5 16 1 1 17 17 17 5 Pentatricopeptide repeat domain RPM2 PF08579.6 EGO59578.1 - 3.4e-05 23.9 0.0 0.0009 19.3 0.0 3.1 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.2 EGO59578.1 - 0.14 11.4 0.1 18 4.7 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial ATPase expression GHMP_kinases_N PF00288.21 EGO59580.1 - 3e-16 59.2 2.0 3e-16 59.2 1.4 1.8 1 1 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGO59580.1 - 2.5e-07 30.7 0.1 1.3e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal Med15 PF09606.5 EGO59581.1 - 0.0017 16.6 18.2 0.0017 16.6 12.6 1.8 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Zn_peptidase PF04228.8 EGO59581.1 - 0.002 17.4 2.9 0.002 17.4 2.0 2.0 2 0 0 2 2 2 1 Putative neutral zinc metallopeptidase DivIC PF04977.10 EGO59581.1 - 9.8 5.7 9.9 24 4.5 6.9 1.6 1 0 0 1 1 1 0 Septum formation initiator Aldedh PF00171.17 EGO59582.1 - 8e-136 453.0 0.0 8.9e-136 452.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGO59582.1 - 1.2e-07 30.7 0.0 1.7e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EGO59582.1 - 0.012 14.8 0.0 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF1489 PF07370.6 EGO59582.1 - 0.046 13.2 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) RRM_6 PF14259.1 EGO59583.1 - 4.6e-07 29.7 0.0 2.4e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO59583.1 - 5.2e-07 29.1 0.0 7e-05 22.3 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO59583.1 - 0.00012 21.8 0.0 0.0017 18.1 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3439 PF11921.3 EGO59583.1 - 0.085 12.6 2.5 0.16 11.7 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 EGO59583.1 - 0.25 9.2 4.9 0.33 8.8 3.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Nop14 PF04147.7 EGO59583.1 - 2 6.1 25.0 0.015 13.3 10.7 1.9 2 0 0 2 2 2 0 Nop14-like family Mucin PF01456.12 EGO59583.1 - 3.1 7.5 12.8 0.13 12.0 4.9 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF572 PF04502.8 EGO59583.1 - 8.3 5.5 24.9 6 5.9 6.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) AAR2 PF05282.6 EGO59583.1 - 9.1 5.0 9.8 0.61 8.9 2.7 1.7 2 0 0 2 2 2 0 AAR2 protein DUF2346 PF09803.4 EGO59584.1 - 0.044 13.6 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) HAD_2 PF13419.1 EGO59585.1 - 9.5e-12 45.4 0.0 8e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO59585.1 - 3.3e-05 23.5 0.0 6.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EGO59585.1 - 0.0011 19.3 0.0 0.018 15.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TPR_11 PF13414.1 EGO59586.1 - 2.2e-14 52.8 4.9 1.5e-13 50.1 1.1 2.3 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EGO59586.1 - 3.4e-06 26.4 6.7 0.00061 19.2 0.6 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGO59586.1 - 7.2e-06 25.8 0.4 7.2e-06 25.8 0.3 2.3 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGO59586.1 - 3e-05 23.6 9.0 0.00076 19.2 0.5 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO59586.1 - 0.0034 18.0 5.2 0.0054 17.3 0.6 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGO59586.1 - 0.028 15.0 6.5 0.061 13.9 0.0 3.4 2 2 2 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EGO59586.1 - 0.051 13.7 0.6 0.13 12.4 0.4 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EGO59586.1 - 0.11 12.3 4.2 2 8.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3677 PF12432.3 EGO59586.1 - 0.11 12.9 0.2 11 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) MIT PF04212.13 EGO59586.1 - 0.86 9.5 7.6 0.97 9.3 0.3 3.3 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EGO59586.1 - 1.5 8.8 0.0 1.5 8.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat NMD3 PF04981.8 EGO59587.1 - 1.6e-72 243.4 3.8 2.5e-72 242.7 2.6 1.3 1 0 0 1 1 1 1 NMD3 family DUF35_N PF12172.3 EGO59587.1 - 0.12 12.3 2.2 0.27 11.1 0.1 2.6 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.2 EGO59587.1 - 0.88 9.4 5.4 0.94 9.3 1.7 2.3 2 0 0 2 2 2 0 Double zinc ribbon HypA PF01155.14 EGO59587.1 - 1.3 8.7 5.0 20 4.9 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family C1_1 PF00130.17 EGO59587.1 - 1.6 8.5 5.6 3.7 7.3 0.7 2.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.16 EGO59587.1 - 1.9 8.4 7.1 4.5 7.2 2.2 2.3 2 0 0 2 2 2 0 FYVE zinc finger DUF1691 PF07950.6 EGO59588.1 - 0.097 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) Nop14 PF04147.7 EGO59588.1 - 2.7 5.8 7.3 3.9 5.2 5.0 1.1 1 0 0 1 1 1 0 Nop14-like family P12 PF12669.2 EGO59588.1 - 7.6 6.8 6.5 1.1 9.5 0.3 2.3 2 0 0 2 2 2 0 Virus attachment protein p12 family Pantoate_ligase PF02569.10 EGO59589.1 - 2.7e-80 269.1 0.0 5.4e-80 268.1 0.0 1.5 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase UPF0086 PF01868.11 EGO59590.1 - 1.7e-24 85.2 0.5 2.8e-24 84.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Acyltransferase PF01553.16 EGO59591.1 - 2.4e-18 65.8 0.0 4.9e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase WD40 PF00400.27 EGO59592.1 - 5.4e-20 70.4 8.2 0.00056 19.6 0.0 6.3 5 1 0 5 5 5 5 WD domain, G-beta repeat Fungal_trans_2 PF11951.3 EGO59593.1 - 1.9e-07 30.0 1.9 3.9e-07 29.0 1.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO59593.1 - 0.0004 20.2 14.5 0.0004 20.2 10.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF966 PF06136.8 EGO59593.1 - 0.0054 16.1 4.6 0.0054 16.1 3.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF966) TSA PF03249.8 EGO59593.1 - 0.34 9.4 4.7 0.61 8.5 3.3 1.3 1 0 0 1 1 1 0 Type specific antigen Med3 PF11593.3 EGO59593.1 - 5.5 6.1 18.8 0.078 12.2 7.8 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Vanabin-2 PF11437.3 EGO59594.1 - 0.013 15.4 0.7 0.016 15.1 0.5 1.1 1 0 0 1 1 1 0 Vanadium-binding protein 2 Peptidase_S8 PF00082.17 EGO59595.1 - 4.6e-06 25.9 1.3 6.9e-06 25.4 0.9 1.2 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.6 EGO59595.1 - 0.1 12.6 0.0 0.39 10.7 0.0 1.8 1 1 1 2 2 2 0 Pro-kumamolisin, activation domain DUF3546 PF12066.3 EGO59596.1 - 0.00061 19.7 0.3 0.0068 16.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) Sec2p PF06428.6 EGO59596.1 - 0.019 14.8 1.4 0.14 12.0 0.1 2.0 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p NAD_binding_10 PF13460.1 EGO59597.1 - 0.0083 16.1 0.1 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Fungal_trans PF04082.13 EGO59598.1 - 4.3e-15 55.3 4.8 7.3e-15 54.5 3.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO59598.1 - 3.7e-09 36.3 7.0 6.2e-09 35.6 4.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGO59599.1 - 2.2e-15 56.2 0.0 4e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO59599.1 - 2.3e-06 27.4 11.3 3.9e-06 26.6 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Serglycin PF04360.7 EGO59600.1 - 0.26 10.9 2.5 5.2 6.7 0.1 3.1 3 0 0 3 3 3 0 Serglycin S1-P1_nuclease PF02265.11 EGO59602.1 - 3.3e-71 239.8 0.0 3.7e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease SinI PF08671.5 EGO59605.1 - 0.069 12.5 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Anti-repressor SinI Metallophos PF00149.23 EGO59606.1 - 1.5e-16 60.3 0.2 1.9e-15 56.8 0.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EGO59606.1 - 3.7e-11 42.9 0.0 7.1e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 EGO59606.1 - 6.8e-06 24.9 0.0 0.00012 20.8 0.0 2.4 1 1 2 3 3 3 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EGO59606.1 - 0.00094 19.0 0.0 0.0024 17.7 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain fn3 PF00041.16 EGO59606.1 - 0.0039 17.2 4.6 0.0072 16.4 3.2 1.4 1 0 0 1 1 1 1 Fibronectin type III domain MFS_1 PF07690.11 EGO59608.1 - 3.7e-26 91.6 44.3 7.5e-25 87.3 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tom5 PF10642.4 EGO59608.1 - 0.071 12.7 0.0 0.69 9.6 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase NAD_binding_10 PF13460.1 EGO59610.1 - 9.2e-10 38.8 0.0 2.2e-07 31.0 0.0 2.6 1 1 0 1 1 1 1 NADH(P)-binding PXA PF02194.10 EGO59610.1 - 0.097 12.2 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 PXA domain Glyco_hydro_7 PF00840.15 EGO59611.1 - 2.2e-212 705.1 27.8 2.8e-212 704.7 19.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 EGO59611.1 - 3.9e-15 55.1 7.1 3.9e-15 55.1 4.9 4.1 5 0 0 5 5 5 1 Fungal cellulose binding domain Gly_transf_sug PF04488.10 EGO59614.1 - 5.2e-11 42.8 0.1 1.4e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caldesmon PF02029.10 EGO59614.1 - 0.0066 14.9 26.4 0.0079 14.6 18.3 1.1 1 0 0 1 1 1 1 Caldesmon DDHD PF02862.12 EGO59614.1 - 0.06 13.1 11.7 0.093 12.5 8.1 1.2 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 EGO59614.1 - 0.86 9.5 14.3 1.2 8.9 9.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4246 PF14033.1 EGO59614.1 - 2.1 6.8 13.4 3 6.3 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) RR_TM4-6 PF06459.7 EGO59614.1 - 2.2 8.1 20.0 2.9 7.7 13.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 U79_P34 PF03064.11 EGO59614.1 - 3.9 6.9 24.0 5.8 6.3 16.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RNA_pol_Rpc4 PF05132.9 EGO59614.1 - 5.6 6.9 11.4 11 5.9 7.9 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 TraH_2 PF06871.6 EGO59614.1 - 9.7 5.5 7.7 17 4.7 5.3 1.3 1 0 0 1 1 1 0 TraH_2 HET PF06985.6 EGO59617.1 - 0.026 14.6 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Transp_cyt_pur PF02133.10 EGO59618.1 - 2.2e-155 517.5 34.4 2.5e-155 517.3 23.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin AAA_5 PF07728.9 EGO59619.1 - 1.7e-09 37.5 0.0 2.6e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EGO59619.1 - 6.6e-07 29.5 0.0 1.6e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UBA_4 PF14555.1 EGO59619.1 - 3.6e-05 23.1 0.7 0.00011 21.6 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain AAA_2 PF07724.9 EGO59619.1 - 0.00023 21.1 0.1 0.0028 17.5 0.0 2.6 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) UBA PF00627.26 EGO59619.1 - 0.00058 19.6 0.1 0.0014 18.3 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain ClpB_D2-small PF10431.4 EGO59619.1 - 0.00059 19.6 0.1 0.0016 18.3 0.0 1.7 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.21 EGO59619.1 - 0.00098 18.6 0.0 0.0041 16.6 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EGO59619.1 - 0.0023 17.9 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EGO59619.1 - 0.0052 15.9 0.0 3.1 6.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EGO59619.1 - 0.0094 16.7 0.0 0.02 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGO59619.1 - 0.019 15.1 0.0 0.082 13.0 0.0 2.1 2 1 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 EGO59619.1 - 0.046 13.7 0.1 3 7.7 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EGO59619.1 - 0.055 13.6 0.0 0.18 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EGO59619.1 - 0.056 13.0 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Ank_3 PF13606.1 EGO59619.1 - 0.062 13.5 0.0 0.6 10.5 0.0 2.7 3 0 0 3 3 1 0 Ankyrin repeat IstB_IS21 PF01695.12 EGO59619.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 EGO59619.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain FMO-like PF00743.14 EGO59621.1 - 5.4e-19 67.7 0.0 3.2e-18 65.2 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGO59621.1 - 1.6e-18 67.4 0.1 4.2e-17 62.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO59621.1 - 1.5e-14 54.3 0.2 5.2e-09 36.2 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGO59621.1 - 2.5e-10 39.7 0.2 6.9e-07 28.5 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EGO59621.1 - 2.2e-06 27.9 6.1 0.013 15.8 1.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO59621.1 - 3.5e-06 26.9 2.0 7.2e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO59621.1 - 2.6e-05 23.3 0.7 0.00027 19.9 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EGO59621.1 - 9.8e-05 22.4 0.5 0.0053 16.8 0.1 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EGO59621.1 - 0.00038 20.6 0.1 0.053 13.7 0.1 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EGO59621.1 - 0.0062 16.3 2.9 0.77 9.5 0.2 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EGO59621.1 - 0.012 15.2 0.2 0.025 14.2 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EGO59621.1 - 0.053 11.9 4.1 0.13 10.7 0.2 2.5 3 0 0 3 3 3 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EGO59621.1 - 0.48 9.9 2.2 11 5.5 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EGO59621.1 - 7.4 5.3 6.9 0.53 9.0 0.4 2.2 3 1 1 4 4 4 0 Glucose inhibited division protein A Sas10_Utp3 PF04000.10 EGO59622.1 - 5.3e-18 64.9 1.9 1.2e-17 63.8 1.3 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family EMP70 PF02990.11 EGO59623.1 - 7.5e-196 651.6 3.8 9.3e-196 651.3 2.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 PIRT PF15099.1 EGO59623.1 - 0.14 11.3 1.8 0.36 10.0 1.3 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Med4 PF10018.4 EGO59625.1 - 3.7e-63 212.3 5.0 4.8e-63 211.9 3.5 1.1 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 ARGLU PF15346.1 EGO59625.1 - 0.019 14.7 23.6 0.019 14.7 16.4 1.9 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 PAT1 PF09770.4 EGO59625.1 - 0.31 9.2 9.8 0.39 8.9 6.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DIE2_ALG10 PF04922.7 EGO59626.1 - 4.6e-72 243.1 17.5 6e-55 186.8 0.3 3.7 3 1 0 3 3 3 3 DIE2/ALG10 family QCR10 PF09796.4 EGO59626.1 - 4.7e-15 54.9 0.4 1.6e-14 53.2 0.0 2.2 2 0 0 2 2 2 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 EGO59626.1 - 0.024 14.3 0.2 0.16 11.7 0.0 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Phage_glycop_gL PF11108.3 EGO59626.1 - 0.065 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Viral glycoprotein L Glyco_hydro_43 PF04616.9 EGO59628.1 - 5.4e-06 25.6 7.8 0.0065 15.5 0.3 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EGO59628.1 - 3.1e-05 23.5 0.7 0.00016 21.1 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Trypsin_2 PF13365.1 EGO59629.1 - 4.5e-15 55.7 0.0 9.6e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EGO59629.1 - 3.8e-05 23.3 0.1 0.00027 20.5 0.0 2.1 1 1 0 1 1 1 1 Trypsin Peptidase_C4 PF00863.14 EGO59629.1 - 0.0079 15.1 0.1 0.015 14.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family C4 Peptidase_S32 PF05579.8 EGO59629.1 - 0.013 14.4 0.1 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.4 EGO59629.1 - 0.015 13.7 0.0 0.1 11.0 0.0 1.9 2 0 0 2 2 2 0 Peptidase S46 KGG PF10685.4 EGO59630.1 - 2e-29 100.8 22.9 3.2e-13 49.2 1.9 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif Glyoxalase PF00903.20 EGO59632.1 - 3.9e-09 36.5 7.1 8.5e-09 35.4 2.5 2.7 2 2 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGO59632.1 - 4e-07 30.6 1.8 0.0011 19.5 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EGO59632.1 - 0.096 12.7 0.9 1 9.4 0.1 2.8 2 2 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Acid_PPase PF12689.2 EGO59633.1 - 8.6e-50 168.6 0.0 5.6e-24 84.6 0.0 2.1 2 0 0 2 2 2 2 Acid Phosphatase HAD_2 PF13419.1 EGO59633.1 - 0.0054 16.9 0.1 8.1 6.6 0.0 2.9 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Serglycin PF04360.7 EGO59633.1 - 0.25 11.0 4.0 0.48 10.1 2.8 1.4 1 0 0 1 1 1 0 Serglycin CRAL_TRIO PF00650.15 EGO59634.1 - 2.9e-26 91.8 0.0 4.6e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGO59634.1 - 3.8e-10 39.7 0.1 9.4e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Coatomer_WDAD PF04053.9 EGO59635.1 - 1.5e-172 574.3 0.0 2.3e-171 570.4 0.0 2.1 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EGO59635.1 - 2.8e-46 153.8 8.9 6.6e-10 38.4 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EGO59635.1 - 6e-06 24.6 4.5 0.0049 15.0 0.1 4.4 1 1 2 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EGO59635.1 - 0.00021 21.0 0.0 0.54 10.0 0.0 3.8 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region YmzC PF14157.1 EGO59635.1 - 0.061 13.1 0.1 28 4.6 0.0 4.0 5 0 0 5 5 5 0 YmzC-like protein Apc4_WD40 PF12894.2 EGO59635.1 - 0.099 12.1 0.0 3.2 7.3 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Mannitol_dh_C PF08125.8 EGO59636.1 - 3.1e-46 157.5 0.2 4.1e-46 157.1 0.2 1.1 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EGO59636.1 - 1.3e-19 70.6 1.8 3.4e-19 69.2 0.0 2.4 3 0 0 3 3 3 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.9 EGO59636.1 - 0.0076 15.6 0.9 0.023 14.0 0.1 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EGO59636.1 - 0.089 12.2 0.3 0.32 10.4 0.0 2.1 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA SapB_1 PF05184.10 EGO59636.1 - 0.15 11.8 1.7 0.54 10.1 0.4 2.6 2 0 0 2 2 2 0 Saposin-like type B, region 1 VWA PF00092.23 EGO59639.1 - 0.0014 18.3 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA PF00004.24 EGO59641.1 - 6.4e-12 45.8 0.0 1.3e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO59641.1 - 1.9e-06 28.0 0.0 4.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGO59641.1 - 4.9e-05 22.4 0.0 0.0001 21.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGO59641.1 - 7.9e-05 22.3 0.2 0.00037 20.1 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EGO59641.1 - 8.8e-05 22.2 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EGO59641.1 - 0.00039 20.3 0.5 0.0021 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EGO59641.1 - 0.00065 18.5 0.0 0.001 17.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EGO59641.1 - 0.00095 19.0 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO59641.1 - 0.0021 18.8 0.0 0.0075 17.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EGO59641.1 - 0.011 14.7 0.0 0.028 13.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.10 EGO59641.1 - 0.013 15.1 0.2 0.034 13.8 0.1 1.7 1 1 0 1 1 1 0 NTPase NB-ARC PF00931.17 EGO59641.1 - 0.018 13.9 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 EGO59641.1 - 0.025 14.8 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGO59641.1 - 0.025 14.5 0.4 0.14 12.1 0.0 2.3 2 1 1 3 3 3 0 AAA ATPase domain DUF258 PF03193.11 EGO59641.1 - 0.027 13.6 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PhoH PF02562.11 EGO59641.1 - 0.037 13.2 0.1 0.56 9.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.12 EGO59641.1 - 0.069 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 EGO59641.1 - 0.24 11.7 0.1 0.24 11.7 0.1 2.1 3 0 0 3 3 1 0 ABC transporter bZIP_2 PF07716.10 EGO59642.1 - 0.0013 18.5 0.9 0.0013 18.5 0.6 2.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EGO59642.1 - 0.0055 16.6 0.2 0.0055 16.6 0.1 2.9 3 0 0 3 3 3 1 bZIP transcription factor Sin3_corepress PF08295.7 EGO59642.1 - 0.015 15.0 2.9 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Sin3 family co-repressor Phage_GP20 PF06810.6 EGO59642.1 - 0.019 14.4 5.4 0.037 13.4 3.7 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 GAS PF13851.1 EGO59642.1 - 0.048 12.8 8.0 0.095 11.8 5.5 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 EGO59642.1 - 0.068 11.0 0.5 0.091 10.5 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-CpG_bind_C PF12269.3 EGO59642.1 - 0.07 12.5 1.9 0.14 11.6 1.3 1.4 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Herpes_ICP4_N PF03584.10 EGO59642.1 - 0.17 11.3 2.0 0.43 10.0 0.3 2.0 2 0 0 2 2 2 0 Herpesvirus ICP4-like protein N-terminal region TPR_MLP1_2 PF07926.7 EGO59642.1 - 0.24 11.1 15.8 0.071 12.8 8.6 1.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EGO59642.1 - 0.45 9.5 6.5 0.76 8.7 4.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Uds1 PF15456.1 EGO59642.1 - 0.66 9.9 10.2 0.03 14.2 2.6 2.0 3 0 0 3 3 3 0 Up-regulated During Septation IncA PF04156.9 EGO59642.1 - 1.3 8.5 7.0 2.3 7.7 4.9 1.4 1 0 0 1 1 1 0 IncA protein Oxidored_q2 PF00420.19 EGO59643.1 - 3.4 7.3 6.9 0.27 10.8 0.8 2.0 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Amidohydro_1 PF01979.15 EGO59646.1 - 3.4e-42 145.2 0.0 4.2e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EGO59646.1 - 1.3e-07 31.1 4.3 1.2e-06 28.0 0.2 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EGO59646.1 - 0.00041 20.0 0.0 0.0018 18.0 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EGO59646.1 - 0.00044 20.3 0.3 0.068 13.1 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase ketoacyl-synt PF00109.21 EGO59647.1 - 1e-19 71.0 0.0 2.1e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EGO59647.1 - 1.7e-19 70.5 0.0 4.3e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 EGO59647.1 - 6.5e-17 61.3 0.0 1.7e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EGO59647.1 - 3.5e-11 43.0 0.0 8e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EGO59647.1 - 0.00015 21.7 0.0 0.00055 19.8 0.0 2.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO59647.1 - 0.013 15.1 0.0 0.045 13.4 0.0 1.9 1 0 0 1 1 1 0 KR domain Acyl_transf_1 PF00698.16 EGO59648.1 - 2.6e-81 273.4 0.0 7.3e-79 265.3 0.0 3.5 3 1 0 3 3 3 2 Acyl transferase domain MaoC_dehydratas PF01575.14 EGO59648.1 - 1.8e-38 130.6 0.0 3.6e-38 129.7 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EGO59648.1 - 9e-31 105.4 0.1 2.4e-30 104.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EGO59648.1 - 5.7e-22 77.9 0.1 5.5e-21 74.7 0.0 2.6 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase FliT PF05400.8 EGO59654.1 - 0.49 10.8 7.1 0.88 10.0 2.4 2.2 1 1 1 2 2 2 0 Flagellar protein FliT VPS9 PF02204.13 EGO59655.1 - 5e-28 97.1 0.0 9.8e-28 96.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EGO59655.1 - 3.2e-09 36.1 1.5 6.2e-08 31.9 0.0 3.0 3 0 0 3 3 3 1 CUE domain DUF3824 PF12868.2 EGO59656.1 - 0.44 11.4 3.7 0.55 11.1 2.5 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF755 PF05501.6 EGO59656.1 - 0.59 10.2 9.7 0.68 9.9 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) BLVR PF06375.6 EGO59656.1 - 0.76 9.5 7.1 0.94 9.2 5.0 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Asn_synthase PF00733.16 EGO59657.1 - 5.2e-63 212.9 0.0 8.1e-63 212.2 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGO59657.1 - 2.7e-10 40.0 0.0 4.5e-09 36.0 0.0 2.9 3 1 0 3 3 3 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGO59657.1 - 0.0008 19.3 0.0 0.0025 17.7 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain PAPS_reduct PF01507.14 EGO59657.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family NAD_synthase PF02540.12 EGO59657.1 - 0.16 10.8 0.0 0.51 9.1 0.0 1.7 2 0 0 2 2 2 0 NAD synthase zf-met PF12874.2 EGO59658.1 - 9.6e-06 25.6 1.6 1.5e-05 25.0 0.7 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 EGO59658.1 - 0.00032 20.2 0.2 0.00048 19.7 0.1 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 EGO59658.1 - 0.056 12.7 0.9 0.098 11.9 0.6 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CoA_transf_3 PF02515.12 EGO59659.1 - 2.1e-58 196.7 0.0 3.8e-58 195.8 0.0 1.5 1 0 0 1 1 1 1 CoA-transferase family III Y_phosphatase3C PF13348.1 EGO59659.1 - 0.12 12.4 0.1 0.32 11.1 0.1 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family C-terminal region PHD PF00628.24 EGO59660.1 - 2.2e-08 33.6 7.8 3.8e-08 32.8 5.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 EGO59660.1 - 0.00034 19.9 2.6 0.00047 19.4 1.3 1.5 1 1 0 1 1 1 1 PHD/FYVE-zinc-finger like domain FYVE_2 PF02318.11 EGO59660.1 - 0.037 13.9 2.4 0.081 12.8 1.6 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Baculo_ME53 PF06061.6 EGO59660.1 - 0.053 12.4 0.0 0.08 11.9 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 PHD_2 PF13831.1 EGO59660.1 - 0.1 11.9 8.6 0.016 14.5 2.4 2.2 2 1 0 2 2 2 0 PHD-finger DUF4414 PF14377.1 EGO59660.1 - 0.11 12.3 1.7 0.33 10.8 1.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) zf-CHY PF05495.7 EGO59660.1 - 0.4 10.8 6.7 7.7 6.7 2.1 2.3 1 1 1 2 2 2 0 CHY zinc finger C1_1 PF00130.17 EGO59660.1 - 0.56 9.9 13.2 0.02 14.6 5.0 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.20 EGO59661.1 - 9.4e-56 188.8 0.2 6.7e-40 136.8 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO59661.1 - 2.1e-26 92.5 0.1 1.3e-20 73.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGO59661.1 - 0.0001 21.4 0.0 0.0002 20.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO59661.1 - 0.00014 21.7 0.2 0.016 14.9 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGO59661.1 - 0.00079 18.5 0.0 0.0017 17.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 EGO59661.1 - 0.043 14.3 0.1 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 EGO59661.1 - 0.056 12.2 0.1 0.087 11.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 EGO59661.1 - 0.092 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 EGO59661.1 - 0.55 9.5 3.8 0.49 9.7 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Tim54 PF11711.3 EGO59662.1 - 2.3e-128 428.0 2.4 3.9e-128 427.2 1.6 1.4 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF2390 PF09523.5 EGO59662.1 - 0.14 12.3 1.1 2.6 8.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) Nefa_Nip30_N PF10187.4 EGO59663.1 - 2.5e-20 72.5 0.1 2.6e-20 72.5 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 UVR PF02151.14 EGO59663.1 - 0.37 10.3 3.7 0.5 9.9 2.3 1.4 1 1 0 1 1 1 0 UvrB/uvrC motif Cyclin PF08613.6 EGO59665.1 - 1.2e-13 51.6 0.0 2.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin DUF221 PF02714.10 EGO59665.1 - 0.0038 16.1 0.0 0.0059 15.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 PSCyt2 PF07583.6 EGO59665.1 - 0.98 8.8 5.1 8.4 5.8 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1549) CRC_subunit PF08624.5 EGO59667.1 - 1.1e-58 197.0 0.0 1.6e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CDC45 PF02724.9 EGO59667.1 - 4.9 5.0 5.4 6.6 4.6 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EGO59667.1 - 6.2 4.6 9.6 8.9 4.0 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIB PF00382.14 EGO59668.1 - 3.9e-38 129.1 3.8 1.5e-20 72.7 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EGO59668.1 - 1.5e-15 56.2 1.0 2.7e-15 55.3 0.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 EGO59668.1 - 0.00091 19.1 0.1 0.58 10.0 0.1 2.6 1 1 2 3 3 3 2 Cyclin, C-terminal domain REC114-like PF15165.1 EGO59668.1 - 0.0012 18.6 0.2 0.0019 17.9 0.1 1.4 1 0 0 1 1 1 1 Meiotic recombination protein REC114-like Sigma70_r4_2 PF08281.7 EGO59668.1 - 0.012 15.1 0.0 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 EGO59668.1 - 0.021 13.9 0.4 0.58 9.3 0.0 3.0 3 1 1 4 4 4 0 Helix-turn-helix domain of transposase family ISL3 Rrf2 PF02082.15 EGO59668.1 - 0.028 14.5 0.0 3.6 7.7 0.0 2.8 2 1 1 3 3 3 0 Transcriptional regulator HTH_24 PF13412.1 EGO59668.1 - 0.068 12.5 0.2 1.9 7.9 0.0 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Cyt-b5 PF00173.23 EGO59670.1 - 2.9e-14 52.5 0.0 3.9e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4291 PF14124.1 EGO59671.1 - 6.9e-70 234.3 0.0 8e-70 234.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Kelch_5 PF13854.1 EGO59672.1 - 3.6e-17 61.9 15.7 1.1e-07 31.6 0.1 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 EGO59672.1 - 7.5e-14 51.2 13.9 4.6e-05 23.4 0.7 5.1 3 1 1 4 4 4 4 Kelch motif Kelch_4 PF13418.1 EGO59672.1 - 4.2e-13 48.8 11.4 0.00082 19.0 0.1 6.0 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EGO59672.1 - 1.5e-12 47.2 24.5 3.8e-05 23.7 0.0 7.0 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_1 PF01344.20 EGO59672.1 - 4.2e-07 29.4 11.8 0.042 13.3 0.2 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EGO59672.1 - 0.011 15.5 10.8 0.41 10.4 0.1 5.1 5 1 0 5 5 5 0 Kelch motif Alpha_GJ PF03229.8 EGO59672.1 - 0.04 14.2 4.9 0.16 12.3 3.4 2.1 1 0 0 1 1 1 0 Alphavirus glycoprotein J Adeno_E3 PF06040.6 EGO59672.1 - 0.14 12.1 1.7 0.64 9.9 0.1 2.3 2 0 0 2 2 2 0 Adenovirus E3 protein FixQ PF05545.6 EGO59672.1 - 0.42 10.2 4.4 0.081 12.5 0.3 1.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF3613 PF12266.3 EGO59673.1 - 0.0031 16.9 0.2 0.61 9.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3613) CUE PF02845.11 EGO59674.1 - 1.4e-06 27.6 0.0 2.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain PGI PF00342.14 EGO59675.1 - 5.5e-213 707.7 1.1 6.3e-213 707.5 0.8 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.20 EGO59676.1 - 5.7e-72 241.9 0.0 7.4e-72 241.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO59676.1 - 8.1e-35 120.1 0.0 1.1e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGO59676.1 - 4.1e-11 43.2 1.4 1.3e-10 41.6 1.0 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGO59676.1 - 0.00067 18.6 0.0 0.0014 17.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGO59676.1 - 0.057 12.4 0.1 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family rve_3 PF13683.1 EGO59678.1 - 0.01 15.3 0.2 2.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain DUF1939 PF09154.5 EGO59679.1 - 0.018 14.9 13.1 5.4 7.0 0.2 5.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1939) Alpha-amylase_C PF02806.13 EGO59679.1 - 0.15 12.2 0.1 1.1e+02 3.0 0.0 3.3 1 1 2 3 3 3 0 Alpha amylase, C-terminal all-beta domain Propep_M14 PF02244.11 EGO59679.1 - 0.59 9.8 1.1 48 3.7 0.0 3.3 3 0 0 3 3 3 0 Carboxypeptidase activation peptide ABC_tran PF00005.22 EGO59680.1 - 2.1e-43 147.9 0.0 1.3e-25 90.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGO59680.1 - 2.2e-27 96.1 7.1 5.6e-15 55.4 1.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EGO59680.1 - 2.1e-10 40.2 1.8 0.0014 17.9 0.0 4.3 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGO59680.1 - 2.5e-08 34.1 2.0 0.004 17.1 0.1 3.9 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 EGO59680.1 - 8.1e-08 32.4 0.2 0.0059 16.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EGO59680.1 - 6.1e-07 29.6 0.0 2.6 7.9 0.1 4.5 3 1 0 3 3 3 2 AAA domain NACHT PF05729.7 EGO59680.1 - 8.3e-07 28.8 0.2 0.016 14.8 0.0 2.8 2 0 0 2 2 2 2 NACHT domain T2SE PF00437.15 EGO59680.1 - 1.8e-06 27.1 1.8 0.003 16.4 0.7 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.1 EGO59680.1 - 3.1e-06 27.6 1.3 0.008 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGO59680.1 - 8.6e-06 25.2 0.0 0.0038 16.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGO59680.1 - 2.6e-05 23.4 0.3 0.019 14.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EGO59680.1 - 0.00026 21.4 0.0 0.059 13.8 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EGO59680.1 - 0.00071 19.0 7.6 0.0056 16.1 0.6 3.0 3 0 0 3 3 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 EGO59680.1 - 0.0026 17.8 0.1 1.4 9.1 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_17 PF13207.1 EGO59680.1 - 0.0047 17.7 0.2 0.048 14.4 0.2 2.6 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGO59680.1 - 0.0054 16.6 0.0 0.37 10.7 0.0 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA PF00004.24 EGO59680.1 - 0.0092 16.1 1.8 1.8 8.8 0.0 3.5 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EGO59680.1 - 0.0098 15.6 0.1 0.9 9.1 0.0 2.9 2 1 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 EGO59680.1 - 0.014 14.8 2.7 1 8.7 0.3 3.4 3 1 1 4 4 4 0 AAA-like domain AAA_18 PF13238.1 EGO59680.1 - 0.015 15.6 0.0 0.3 11.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EGO59680.1 - 0.017 15.0 0.0 8.1 6.4 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.14 EGO59680.1 - 0.017 14.5 1.0 4.6 6.6 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EGO59680.1 - 0.019 14.4 0.4 2.5 7.5 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 EGO59680.1 - 0.021 14.5 2.0 2.2 7.9 0.2 2.6 2 0 0 2 2 2 0 NTPase MobB PF03205.9 EGO59680.1 - 0.022 14.4 0.7 1.7 8.3 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EGO59680.1 - 0.029 14.2 0.1 6 6.6 0.0 2.8 2 0 0 2 2 2 0 Dynamin family DUF962 PF06127.6 EGO59680.1 - 0.04 13.8 0.5 0.85 9.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF962) DUF2075 PF09848.4 EGO59680.1 - 0.044 12.7 0.2 1.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EGO59680.1 - 0.056 12.9 0.3 8.1 5.9 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_13 PF13166.1 EGO59680.1 - 0.056 11.9 0.1 0.34 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGO59680.1 - 0.066 13.0 0.0 13 5.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EGO59680.1 - 0.084 12.2 4.2 8.9 5.6 0.1 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_19 PF13245.1 EGO59680.1 - 0.11 12.2 3.1 3 7.6 0.8 3.2 2 0 0 2 2 2 0 Part of AAA domain DUF87 PF01935.12 EGO59680.1 - 0.13 12.0 2.5 0.13 12.0 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EGO59680.1 - 0.14 11.2 0.4 12 4.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Podoplanin PF05808.6 EGO59681.1 - 0.0018 17.8 1.7 0.0028 17.2 1.2 1.3 1 0 0 1 1 1 1 Podoplanin Rifin_STEVOR PF02009.11 EGO59681.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family SPASM PF13186.1 EGO59682.1 - 0.51 10.7 6.1 0.18 12.1 0.6 2.6 2 1 0 2 2 2 0 Iron-sulfur cluster-binding domain Polyketide_cyc2 PF10604.4 EGO59683.1 - 4.4e-05 23.6 0.1 5.1e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Lactamase_B_2 PF12706.2 EGO59685.1 - 1.9e-39 135.2 0.0 2.5e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGO59685.1 - 1.9e-11 43.9 0.0 3.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGO59685.1 - 1.5e-06 28.0 0.1 2.6e-05 23.9 0.0 2.4 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily DUF218 PF02698.12 EGO59686.1 - 2.4e-19 69.3 0.0 4.8e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 DUF218 domain Chorion_2 PF03964.10 EGO59686.1 - 0.0011 19.4 2.9 0.02 15.3 0.0 2.8 2 0 0 2 2 2 1 Chorion family 2 Herpes_capsid PF06112.6 EGO59686.1 - 7.8 6.5 19.8 2.7 8.0 0.2 3.3 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein Glyco_hydro_92 PF07971.7 EGO59687.1 - 8.7e-138 460.0 0.6 2.1e-111 373.0 0.2 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 92 PAS_9 PF13426.1 EGO59689.1 - 4e-16 59.2 0.0 5e-15 55.7 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EGO59689.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 PAS fold Pyridox_oxidase PF01243.15 EGO59690.1 - 1.8e-08 34.3 0.0 3.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TP_methylase PF00590.15 EGO59691.1 - 3e-21 76.0 0.0 4.7e-21 75.4 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.3 EGO59692.1 - 8e-06 25.8 0.2 1.9e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGO59692.1 - 4.3e-05 23.5 0.2 7.4e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 EGO59692.1 - 8.6e-05 22.3 12.7 8.6e-05 22.3 8.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-DBF PF07535.7 EGO59692.1 - 0.024 14.3 0.1 0.062 12.9 0.0 1.7 1 0 0 1 1 1 0 DBF zinc finger KfrA_N PF11740.3 EGO59692.1 - 0.032 14.6 9.1 0.032 14.6 6.3 2.1 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term UQ_con PF00179.21 EGO59693.1 - 7.4e-39 132.3 0.0 9e-39 132.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO59693.1 - 0.00021 21.0 0.2 0.001 18.8 0.1 1.9 1 1 1 2 2 2 1 Prokaryotic E2 family B Mito_carr PF00153.22 EGO59694.1 - 1.2e-57 191.6 9.0 2.2e-20 72.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tox-WTIP PF15654.1 EGO59694.1 - 0.26 10.9 4.8 0.24 11.0 0.1 3.0 3 0 0 3 3 3 0 Toxin with a conserved tryptophan and TIP tripeptide motif Cation_efflux PF01545.16 EGO59695.1 - 1.8e-61 207.7 3.1 2.4e-61 207.3 2.2 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EGO59695.1 - 0.0023 16.9 21.4 0.0023 16.9 14.9 3.2 2 1 0 2 2 2 1 ZIP Zinc transporter Glyco_trans_1_4 PF13692.1 EGO59696.1 - 1.1e-19 70.9 0.0 2.5e-19 69.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_56 PF07429.6 EGO59696.1 - 0.14 11.1 0.0 0.7 8.7 0.0 1.8 2 0 0 2 2 2 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 TFIIIC_delta PF12657.2 EGO59697.1 - 2.5e-17 63.1 0.0 6.1e-08 32.5 0.0 2.9 2 0 0 2 2 2 2 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EGO59697.1 - 6.6e-06 25.9 3.8 1.7e-05 24.6 0.4 2.7 2 1 1 3 3 3 1 Putative zinc-finger of transcription factor IIIC complex Peptidase_C13 PF01650.13 EGO59698.1 - 4.3e-41 140.9 0.4 6.1e-41 140.4 0.2 1.2 1 0 0 1 1 1 1 Peptidase C13 family His_Phos_1 PF00300.17 EGO59699.1 - 1.5e-07 31.6 0.1 7.8e-07 29.3 0.0 2.1 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) F-box-like PF12937.2 EGO59700.1 - 3.5e-06 26.6 0.3 9.1e-06 25.3 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO59700.1 - 0.0023 17.5 0.2 0.0055 16.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain Inhibitor_I34 PF10466.4 EGO59701.1 - 0.1 12.6 0.2 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Saccharopepsin inhibitor I34 DUF4238 PF14022.1 EGO59703.1 - 5.4e-30 104.5 0.5 7.9e-30 104.0 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Cytochrom_B561 PF03188.11 EGO59705.1 - 0.00024 20.9 6.1 0.00024 20.9 4.2 2.2 3 1 0 3 3 3 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EGO59705.1 - 0.00028 20.4 1.6 0.00028 20.4 1.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Tetraspannin PF00335.15 EGO59705.1 - 0.0023 17.2 2.7 0.0056 15.9 0.6 2.2 1 1 1 2 2 2 1 Tetraspanin family DUF4381 PF14316.1 EGO59705.1 - 0.014 15.5 1.0 0.014 15.5 0.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Abhydrolase_9_N PF15420.1 EGO59705.1 - 0.049 13.3 1.9 1.4 8.6 0.2 2.5 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF2231 PF09990.4 EGO59705.1 - 0.14 12.4 13.9 1.1 9.5 3.7 3.1 1 1 2 3 3 3 0 Predicted membrane protein (DUF2231) Glyco_hydro_72 PF03198.9 EGO59706.1 - 1.1e-116 389.2 2.7 1.4e-116 388.9 1.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EGO59706.1 - 9.1e-05 21.7 0.4 0.0013 18.0 0.3 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Serglycin PF04360.7 EGO59706.1 - 0.00087 19.0 3.8 0.0017 18.0 2.7 1.5 1 0 0 1 1 1 1 Serglycin AF-4 PF05110.8 EGO59706.1 - 0.29 8.9 3.1 0.38 8.5 2.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MARVEL PF01284.18 EGO59707.1 - 0.01 15.6 1.9 0.014 15.2 1.3 1.2 1 0 0 1 1 1 0 Membrane-associating domain U1snRNP70_N PF12220.3 EGO59707.1 - 0.095 13.0 0.9 0.14 12.5 0.6 1.2 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal FtsX PF02687.16 EGO59707.1 - 1.9 8.2 5.8 2.6 7.8 4.0 1.2 1 0 0 1 1 1 0 FtsX-like permease family HAUS6_N PF14661.1 EGO59708.1 - 1.3e-61 208.1 2.3 1.3e-61 208.1 1.6 1.8 3 0 0 3 3 3 1 HAUS augmin-like complex subunit 6 N-terminus Ribosomal_S21 PF01165.15 EGO59709.1 - 2.6e-13 49.2 4.8 4e-13 48.5 3.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 DUF605 PF04652.11 EGO59709.1 - 1.4 8.2 7.8 1.7 7.9 5.4 1.1 1 0 0 1 1 1 0 Vta1 like PWI PF01480.12 EGO59710.1 - 6.6e-10 38.9 0.4 1.8e-09 37.5 0.3 1.8 1 0 0 1 1 1 1 PWI domain ECH PF00378.15 EGO59711.1 - 1.1e-48 165.5 0.2 4.2e-38 130.8 0.6 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Glyco_hydro_28 PF00295.12 EGO59712.1 - 5.5e-42 143.8 0.3 7.8e-42 143.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Peptidase_S26 PF10502.4 EGO59713.1 - 0.0091 15.5 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Acetyltransf_1 PF00583.19 EGO59714.1 - 8.2e-07 28.9 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGO59714.1 - 5.5e-06 26.4 0.0 7.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO59714.1 - 0.0079 15.9 0.0 0.017 14.8 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EGO59714.1 - 0.031 14.4 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Thoc2 PF11732.3 EGO59714.1 - 0.099 12.4 0.0 0.82 9.4 0.0 2.3 3 0 0 3 3 3 0 Transcription- and export-related complex subunit Acetyltransf_9 PF13527.1 EGO59714.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TauD PF02668.11 EGO59716.1 - 1.9e-32 112.9 0.1 2.6e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EGO59716.1 - 0.0079 15.1 0.4 0.019 13.8 0.1 1.6 2 0 0 2 2 2 1 CsiD Ank_2 PF12796.2 EGO59717.1 - 4.3e-33 113.5 8.6 6.8e-19 67.9 1.7 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGO59717.1 - 4.2e-19 67.3 5.8 1.9e-08 33.6 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EGO59717.1 - 5.7e-18 64.5 5.7 1.2e-07 31.7 0.3 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO59717.1 - 1.9e-17 61.5 1.9 4.3e-06 26.4 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EGO59717.1 - 6.5e-15 55.1 0.8 1.3e-08 35.1 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) bZIP_1 PF00170.16 EGO59717.1 - 0.00037 20.3 6.6 0.00063 19.6 4.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGO59717.1 - 0.1 12.4 5.8 0.18 11.6 4.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Rhodanese PF00581.15 EGO59718.1 - 2.7e-13 50.2 0.1 1.6e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain DUF4366 PF14283.1 EGO59719.1 - 0.022 14.1 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2207 PF09972.4 EGO59719.1 - 0.028 13.0 0.0 0.039 12.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4407 PF14362.1 EGO59719.1 - 0.034 13.1 0.0 0.034 13.1 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) DUF4083 PF13314.1 EGO59719.1 - 0.077 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) MSC PF09402.5 EGO59719.1 - 0.18 10.5 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Rifin_STEVOR PF02009.11 EGO59719.1 - 1.3 8.5 6.4 4.5 6.8 4.4 1.8 1 1 0 1 1 1 0 Rifin/stevor family UPF0121 PF03661.8 EGO59720.1 - 3e-11 42.9 3.0 5.1e-11 42.2 2.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) YGGT PF02325.12 EGO59720.1 - 0.31 11.0 0.1 0.31 11.0 0.1 2.9 3 0 0 3 3 3 0 YGGT family DSPc PF00782.15 EGO59721.1 - 1.1e-09 38.0 0.0 2.2e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGO59721.1 - 0.0015 17.9 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EGO59721.1 - 0.046 13.9 1.1 0.093 12.9 0.1 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family Pribosyltran_N PF13793.1 EGO59722.1 - 9.5e-42 141.4 0.5 9.5e-41 138.1 0.1 2.6 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EGO59722.1 - 1.4e-40 139.0 2.0 1.7e-35 122.4 0.2 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EGO59722.1 - 5e-12 45.6 0.2 1.4e-11 44.2 0.1 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGO59722.1 - 0.0014 17.8 0.1 0.0029 16.8 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.3 EGO59722.1 - 0.045 13.4 1.1 0.13 12.0 0.7 1.9 1 1 0 1 1 1 0 Chlorosome envelope protein C DUF218 PF02698.12 EGO59722.1 - 0.098 12.1 0.2 1.6 8.1 0.0 2.5 2 1 1 3 3 3 0 DUF218 domain Fungal_trans PF04082.13 EGO59723.1 - 4.4e-29 101.1 0.0 1.1e-28 99.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO59723.1 - 2.2e-09 37.0 7.6 3.5e-09 36.4 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4306 PF14154.1 EGO59723.1 - 0.24 11.3 0.2 0.47 10.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Dynamin_N PF00350.18 EGO59724.1 - 5.2e-17 62.1 0.0 5.5e-15 55.5 0.0 2.5 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGO59724.1 - 8.9e-12 44.3 0.0 1.8e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 EGO59724.1 - 1.7e-06 27.8 0.1 3.9e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain AAA_28 PF13521.1 EGO59724.1 - 0.0035 17.3 0.1 0.021 14.8 0.1 2.2 1 1 1 2 2 2 1 AAA domain Miro PF08477.8 EGO59724.1 - 0.0072 16.8 0.0 0.018 15.5 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EGO59724.1 - 0.022 14.2 0.7 8.2 5.9 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EGO59724.1 - 0.042 14.1 0.0 0.12 12.6 0.0 2.0 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 EGO59724.1 - 0.068 13.1 0.1 0.25 11.3 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase D5_N PF08706.6 EGO59724.1 - 0.1 12.7 0.4 0.42 10.6 0.1 2.1 2 0 0 2 2 2 0 D5 N terminal like PHP PF02811.14 EGO59725.1 - 8.4e-07 28.9 0.0 1.6e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 PHP domain DHC_N1 PF08385.7 EGO59726.1 - 1.2e-196 654.5 5.4 1.2e-196 654.5 3.7 5.1 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EGO59726.1 - 7.1e-128 426.5 10.0 7.1e-128 426.5 6.9 4.8 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EGO59726.1 - 1.8e-104 350.2 0.0 4.8e-104 348.8 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EGO59726.1 - 1.7e-63 214.2 0.0 4.4e-63 212.8 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EGO59726.1 - 6.6e-43 146.1 1.4 1.2e-42 145.2 0.1 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EGO59726.1 - 2e-41 141.7 0.1 3.6e-40 137.6 0.0 2.6 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 EGO59726.1 - 2.3e-38 131.8 8.6 2.3e-38 131.8 5.9 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EGO59726.1 - 1.6e-31 108.8 0.0 4.3e-12 45.9 0.0 5.7 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EGO59726.1 - 4.9e-20 71.7 0.0 1e-18 67.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EGO59726.1 - 6.6e-16 58.6 0.1 0.015 15.4 0.0 6.3 5 1 1 6 6 5 4 AAA domain AAA PF00004.24 EGO59726.1 - 1.9e-13 50.7 0.0 0.002 18.3 0.0 4.9 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGO59726.1 - 2.3e-10 41.3 0.0 0.031 15.1 0.0 6.0 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 EGO59726.1 - 7.7e-10 38.8 0.1 0.36 10.7 0.0 5.4 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.1 EGO59726.1 - 5.8e-09 36.3 1.3 0.025 14.9 0.0 5.7 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.1 EGO59726.1 - 9.4e-08 32.2 21.1 0.07 13.1 0.0 9.4 9 1 1 10 10 9 2 AAA ATPase domain T2SE PF00437.15 EGO59726.1 - 2.6e-07 29.8 0.0 0.063 12.1 0.0 3.7 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_14 PF13173.1 EGO59726.1 - 2.1e-06 27.6 0.0 0.23 11.3 0.0 5.4 5 0 0 5 5 4 1 AAA domain AAA_29 PF13555.1 EGO59726.1 - 2.9e-06 26.7 0.0 0.44 10.1 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_19 PF13245.1 EGO59726.1 - 1.9e-05 24.3 0.0 0.89 9.3 0.0 4.6 4 0 0 4 4 4 1 Part of AAA domain Mg_chelatase PF01078.16 EGO59726.1 - 3.4e-05 23.1 0.4 0.51 9.4 0.0 3.9 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EGO59726.1 - 6e-05 23.3 0.1 3.9 7.7 0.0 5.0 3 0 0 3 3 3 1 ABC transporter Zeta_toxin PF06414.7 EGO59726.1 - 0.00011 21.3 0.0 0.99 8.4 0.0 4.0 3 0 0 3 3 3 2 Zeta toxin FtsK_SpoIIIE PF01580.13 EGO59726.1 - 0.00065 19.2 2.8 6.2 6.2 0.0 4.7 5 0 0 5 5 5 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 EGO59726.1 - 0.0029 17.7 0.0 19 5.4 0.0 4.5 4 0 0 4 4 4 0 RNA helicase MobB PF03205.9 EGO59726.1 - 0.026 14.2 0.1 12 5.5 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EGO59726.1 - 0.047 13.0 3.9 0.38 10.1 0.0 3.8 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.4 EGO59726.1 - 0.31 10.5 3.3 7.1 6.1 0.1 4.2 5 0 0 5 5 4 0 Ethanolamine utilisation - propanediol utilisation Phage_Coat_B PF05356.6 EGO59726.1 - 0.35 10.5 0.0 0.96 9.1 0.0 1.8 1 0 0 1 1 1 0 Phage Coat protein B ERM PF00769.14 EGO59726.1 - 1.3 8.5 31.3 0.37 10.2 8.1 3.4 3 0 0 3 3 2 0 Ezrin/radixin/moesin family MarB PF13999.1 EGO59727.1 - 0.055 13.0 0.1 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 MarB protein DUF1774 PF08611.5 EGO59728.1 - 2.4e-37 126.9 4.8 2.4e-37 126.9 3.3 2.4 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) ACPS PF01648.15 EGO59729.1 - 5.7e-06 26.1 0.1 0.00039 20.2 0.0 2.4 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Menin PF05053.8 EGO59729.1 - 1.7 6.7 6.3 2.6 6.1 4.4 1.2 1 0 0 1 1 1 0 Menin Macoilin PF09726.4 EGO59729.1 - 2.8 6.1 7.8 4.1 5.5 5.4 1.3 1 0 0 1 1 1 0 Transmembrane protein Dynamin_N PF00350.18 EGO59731.1 - 1.2e-14 54.4 0.0 1.2e-14 54.4 0.0 3.6 2 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EGO59731.1 - 0.00012 22.0 0.1 0.0035 17.2 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGO59731.1 - 0.0062 17.0 0.2 0.034 14.6 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 EGO59731.1 - 0.0066 16.7 2.7 0.013 15.7 0.0 2.8 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.1 EGO59731.1 - 0.017 15.1 0.2 0.1 12.5 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain DUF972 PF06156.8 EGO59731.1 - 0.044 14.1 17.8 0.41 11.0 2.2 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) AAA_29 PF13555.1 EGO59731.1 - 0.085 12.3 0.2 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain TBPIP PF07106.8 EGO59731.1 - 0.086 12.3 24.2 0.19 11.2 3.6 3.2 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_22 PF13401.1 EGO59731.1 - 0.1 12.7 0.3 1.1 9.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EGO59731.1 - 0.42 11.4 4.2 0.71 10.7 0.0 3.4 3 1 0 3 3 3 0 AAA domain IncA PF04156.9 EGO59731.1 - 3.7 7.0 23.4 1.4 8.4 3.7 3.7 3 0 0 3 3 3 0 IncA protein Med9 PF07544.8 EGO59731.1 - 7.5 6.3 18.8 1.1 9.0 1.6 3.6 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 V_ATPase_I PF01496.14 EGO59731.1 - 9.7 3.9 16.6 5.3 4.7 1.5 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family WSC PF01822.14 EGO59733.1 - 1.4e-11 44.1 11.1 1.4e-11 44.1 7.7 2.1 2 1 0 2 2 2 1 WSC domain Rax2 PF12768.2 EGO59733.1 - 0.0021 17.3 0.3 0.0056 15.9 0.0 1.7 1 1 0 1 1 1 1 Cortical protein marker for cell polarity Rifin_STEVOR PF02009.11 EGO59733.1 - 2.2 7.8 4.5 6.7 6.2 2.8 1.8 1 1 1 2 2 2 0 Rifin/stevor family YajC PF02699.10 EGO59736.1 - 4e-05 23.1 0.0 0.0022 17.6 0.0 2.4 2 0 0 2 2 2 1 Preprotein translocase subunit SKG6 PF08693.5 EGO59736.1 - 0.00015 20.9 0.2 0.0014 17.8 0.2 2.4 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4381 PF14316.1 EGO59736.1 - 0.021 14.9 1.5 0.044 13.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4448 PF14610.1 EGO59736.1 - 0.049 13.1 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF1049 PF06305.6 EGO59736.1 - 0.35 10.3 1.4 0.89 9.0 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) IncA PF04156.9 EGO59737.1 - 0.0028 17.2 8.3 0.0069 15.9 5.8 1.6 1 0 0 1 1 1 1 IncA protein DUF4407 PF14362.1 EGO59737.1 - 0.094 11.6 6.4 0.16 10.8 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.10 EGO59737.1 - 0.23 10.9 13.1 0.34 10.4 1.2 2.9 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 EGO59737.1 - 0.28 11.0 14.2 1.5 8.7 9.8 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.14 EGO59737.1 - 0.3 8.8 8.3 0.48 8.2 5.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EGO59737.1 - 0.35 9.7 10.7 0.61 8.9 7.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4200 PF13863.1 EGO59737.1 - 0.41 10.5 17.2 0.23 11.3 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FCH PF00611.18 EGO59737.1 - 0.47 10.6 10.7 0.38 10.9 1.9 3.2 2 1 1 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain DUF904 PF06005.7 EGO59737.1 - 0.58 10.4 16.5 0.12 12.6 2.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF904) GAS PF13851.1 EGO59737.1 - 0.78 8.8 17.9 0.49 9.5 4.5 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF883 PF05957.8 EGO59737.1 - 1.9 8.9 8.1 3.2 8.2 4.6 2.2 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF883) Spc7 PF08317.6 EGO59737.1 - 2.3 6.7 14.1 4.1 5.9 9.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 EGO59737.1 - 2.6 6.9 13.1 5.5 5.9 9.1 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIVA PF05103.8 EGO59737.1 - 3.2 7.8 11.8 6.5 6.8 7.6 1.9 2 0 0 2 2 2 0 DivIVA protein DUF3450 PF11932.3 EGO59737.1 - 6.5 5.9 13.1 2.5 7.2 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.17 EGO59737.1 - 10 6.2 14.2 1.5e+02 2.4 9.7 2.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF221 PF02714.10 EGO59738.1 - 1.6e-107 359.1 22.1 1.6e-107 359.1 15.3 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGO59738.1 - 3.1e-46 156.7 2.9 3.1e-46 156.7 2.0 3.4 4 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EGO59738.1 - 7.8e-31 105.8 0.0 1.6e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EGO59738.1 - 5.3e-22 78.1 0.5 9.4e-22 77.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Colicin_V PF02674.11 EGO59738.1 - 0.00067 19.5 6.5 0.00067 19.5 4.5 3.5 3 1 0 3 3 3 1 Colicin V production protein TMEM154 PF15102.1 EGO59738.1 - 6 6.5 6.8 8.6 6.0 0.0 3.0 3 0 0 3 3 3 0 TMEM154 protein family Solute_trans_a PF03619.11 EGO59739.1 - 1.3e-82 277.2 20.4 1.5e-82 277.0 14.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF912 PF06024.7 EGO59739.1 - 0.1 12.6 0.3 2.9 8.0 0.0 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RinB PF06116.7 EGO59739.1 - 0.67 9.6 4.5 0.89 9.2 0.4 2.4 2 0 0 2 2 2 0 Transcriptional activator RinB PrgI PF12666.2 EGO59739.1 - 2.1 8.5 8.3 0.28 11.3 0.3 2.7 2 1 1 3 3 3 0 PrgI family protein Spc97_Spc98 PF04130.8 EGO59740.1 - 3.8e-71 240.0 0.0 6.8e-71 239.2 0.0 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family TA0956 PF11513.3 EGO59740.1 - 0.1 12.6 0.1 29 4.7 0.0 2.8 3 0 0 3 3 3 0 Thermoplasma acidophilum protein TA0956 Senescence PF06911.7 EGO59741.1 - 2.9e-44 150.9 0.1 4.1e-44 150.4 0.1 1.2 1 0 0 1 1 1 1 Senescence-associated protein DUF4087 PF13316.1 EGO59741.1 - 0.03 14.4 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4087) Fungal_trans PF04082.13 EGO59742.1 - 6.1e-20 71.1 0.0 1.2e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SMC_Nse1 PF07574.8 EGO59744.1 - 2.5e-59 200.2 0.0 3.5e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EGO59744.1 - 8.3e-15 54.5 9.6 1.3e-14 53.8 6.6 1.3 1 0 0 1 1 1 1 RING-like domain FYDLN_acid PF09538.5 EGO59744.1 - 0.032 14.8 1.0 0.1 13.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Mrr_N PF14338.1 EGO59744.1 - 0.083 12.9 0.8 3.1 7.9 0.0 3.3 4 0 0 4 4 4 0 Mrr N-terminal domain zf-tcix PF14952.1 EGO59744.1 - 0.099 11.9 0.2 0.099 11.9 0.1 2.1 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding PaaX PF07848.7 EGO59744.1 - 0.11 12.5 0.1 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 PaaX-like protein UPF0547 PF10571.4 EGO59744.1 - 0.33 10.6 3.7 0.57 9.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-Apc11 PF12861.2 EGO59744.1 - 0.69 9.7 4.5 1.1 9.0 3.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 EGO59744.1 - 0.77 9.5 8.9 0.08 12.6 2.3 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SPRY PF00622.23 EGO59746.1 - 4.1e-11 43.0 0.0 8.8e-10 38.7 0.0 2.7 3 0 0 3 3 3 1 SPRY domain Myb_Cef PF11831.3 EGO59747.1 - 3.1e-66 222.8 9.6 3.1e-66 222.8 6.6 2.9 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.1 EGO59747.1 - 1.5e-21 76.2 8.8 5.2e-15 55.2 2.2 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGO59747.1 - 1.4e-20 73.0 4.2 2.3e-09 37.1 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 EGO59747.1 - 0.02 14.7 1.4 0.69 9.8 0.0 3.4 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3306 PF11748.3 EGO59748.1 - 0.2 12.3 5.8 1.6 9.4 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Nop14 PF04147.7 EGO59748.1 - 0.25 9.2 4.9 0.26 9.1 3.4 1.0 1 0 0 1 1 1 0 Nop14-like family Hexokinase_1 PF00349.16 EGO59749.1 - 7.6e-26 90.7 0.0 1.2e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EGO59749.1 - 7.4e-22 77.7 0.0 1.9e-21 76.4 0.0 1.6 1 1 0 1 1 1 1 Hexokinase GILT PF03227.11 EGO59750.1 - 8.8e-13 48.0 0.5 1.5e-12 47.3 0.1 1.6 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) GRAM PF02893.15 EGO59751.1 - 1.5e-17 62.8 0.0 2.7e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 GRAM domain DUF4546 PF15079.1 EGO59752.1 - 0.011 14.8 0.6 0.011 14.8 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4546) Tropomyosin_1 PF12718.2 EGO59752.1 - 0.014 15.2 8.2 0.026 14.3 1.8 2.6 2 0 0 2 2 2 0 Tropomyosin like CCDC155 PF14662.1 EGO59752.1 - 0.021 14.4 10.5 0.29 10.7 3.0 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Ax_dynein_light PF10211.4 EGO59752.1 - 0.034 13.9 9.0 1.5 8.6 3.2 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain Atg14 PF10186.4 EGO59752.1 - 0.046 12.6 2.0 0.091 11.6 1.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 EGO59752.1 - 0.047 13.5 6.0 0.29 10.9 0.8 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 EGO59752.1 - 0.048 14.0 7.4 0.38 11.1 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 EGO59752.1 - 0.18 11.7 8.8 1.9 8.4 0.0 2.9 2 1 0 2 2 2 0 bZIP transcription factor Matrilin_ccoil PF10393.4 EGO59752.1 - 0.27 10.6 1.2 4.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin TBPIP PF07106.8 EGO59752.1 - 0.42 10.1 7.1 0.68 9.4 1.5 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATG16 PF08614.6 EGO59752.1 - 0.72 9.6 15.9 0.022 14.6 4.0 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Prefoldin_2 PF01920.15 EGO59752.1 - 0.78 9.5 6.5 1.8 8.3 1.5 2.4 2 0 0 2 2 2 0 Prefoldin subunit DUF4201 PF13870.1 EGO59752.1 - 1.1 8.6 11.1 0.88 8.9 2.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) GAS PF13851.1 EGO59752.1 - 1.3 8.1 10.5 1.6 7.8 3.0 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.6 EGO59752.1 - 1.4 8.8 4.6 1.9 8.4 0.6 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIVA PF05103.8 EGO59752.1 - 5.6 7.0 17.5 0.63 10.1 2.5 3.2 3 0 0 3 3 3 0 DivIVA protein ADIP PF11559.3 EGO59752.1 - 9.8 6.0 10.9 4.6 7.1 3.1 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Abhydrolase_1 PF00561.15 EGO59753.1 - 3.1e-47 161.0 0.2 3.5e-25 88.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGO59753.1 - 4.2e-14 52.9 3.3 7.4e-13 48.9 2.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO59753.1 - 0.0054 16.4 0.1 0.079 12.7 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EGO59753.1 - 0.082 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Tho2 PF11262.3 EGO59754.1 - 3e-92 308.8 4.1 4.1e-92 308.4 2.8 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EGO59754.1 - 2.2e-28 97.8 0.4 6.1e-28 96.4 0.1 2.0 2 0 0 2 2 2 1 Transcription- and export-related complex subunit 4HB_MCP_1 PF12729.2 EGO59754.1 - 0.79 9.0 1.9 1.6 8.0 1.3 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction YtxC PF08812.6 EGO59754.1 - 0.99 8.8 1.4 2.1 7.7 1.0 1.4 1 0 0 1 1 1 0 YtxC-like family TFCD_C PF12612.3 EGO59755.1 - 1e-29 103.3 7.5 6e-28 97.5 3.2 3.3 2 1 0 2 2 2 1 Tubulin folding cofactor D C terminal Cnd1 PF12717.2 EGO59755.1 - 0.0014 18.5 0.9 0.78 9.5 0.1 4.4 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EGO59755.1 - 0.0085 16.0 7.6 0.13 12.4 0.0 5.7 7 0 0 7 7 7 1 HEAT repeat Glyco_hydro_76 PF03663.9 EGO59756.1 - 3.6e-44 151.6 10.1 1.1e-43 149.9 6.9 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EGO59756.1 - 8e-05 21.8 0.4 0.0089 15.1 0.0 2.6 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Fungal_trans PF04082.13 EGO59757.1 - 3.6e-22 78.5 5.5 6.2e-22 77.7 3.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO59757.1 - 2.2e-09 37.0 9.3 2.2e-09 37.0 6.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPE65 PF03055.10 EGO59758.1 - 1.5e-138 462.4 0.0 1.7e-138 462.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF2296 PF10058.4 EGO59759.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.2 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) His_Phos_2 PF00328.17 EGO59761.1 - 7.4e-136 453.0 0.0 1e-135 452.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EGO59761.1 - 8.9e-09 35.0 0.0 1.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 EGO59762.1 - 1.2e-89 299.5 0.2 1.7e-89 299.0 0.1 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EGO59762.1 - 1.3e-26 91.4 19.1 2.8e-06 26.9 0.3 8.7 9 0 0 9 9 9 5 WD domain, G-beta repeat Nup160 PF11715.3 EGO59762.1 - 2.1e-05 22.8 0.3 0.53 8.3 0.0 3.8 3 1 0 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EGO59762.1 - 0.00012 20.5 0.0 0.00026 19.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EGO59762.1 - 0.081 11.6 0.3 8.9 4.9 0.0 2.6 1 1 1 2 2 2 0 Nup133 N terminal like eIF2A PF08662.6 EGO59762.1 - 0.11 12.1 0.1 2.5 7.7 0.0 3.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A SH3_1 PF00018.23 EGO59763.1 - 2e-09 36.7 0.2 4.7e-09 35.4 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGO59763.1 - 6.3e-08 32.0 0.1 1.4e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGO59763.1 - 8.3e-08 31.5 0.1 1.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain RPAP2_Rtr1 PF04181.8 EGO59764.1 - 1e-18 67.1 0.2 2.2e-18 66.0 0.2 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family Ribosomal_S17e PF00833.13 EGO59765.1 - 2.5e-58 195.1 0.4 3e-58 194.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EGO59765.1 - 0.036 14.7 0.0 0.049 14.3 0.0 1.2 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Mit_ribos_Mrp51 PF11709.3 EGO59766.1 - 1.3e-108 362.9 0.1 1.5e-108 362.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit TGT PF01702.13 EGO59767.1 - 2.9e-87 291.9 0.0 3.8e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Hist_deacetyl PF00850.14 EGO59770.1 - 2.2e-62 211.1 0.1 3.4e-62 210.5 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.16 EGO59771.1 - 3.5e-10 39.6 0.1 1.2e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Vps5 PF09325.5 EGO59772.1 - 1.3e-14 54.0 1.3 2.1e-14 53.3 0.9 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EGO59772.1 - 3.5e-08 33.2 0.0 7.4e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 PX domain PAT1 PF09770.4 EGO59772.1 - 0.017 13.3 37.8 0.027 12.7 26.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EGO59772.1 - 0.9 8.8 27.5 1.5 8.1 19.1 1.3 1 0 0 1 1 1 0 Vta1 like GTP_EFTU PF00009.22 EGO59773.1 - 7.3e-35 120.1 0.0 3.1e-34 118.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EGO59773.1 - 9.6e-23 79.8 0.1 5.2e-22 77.4 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.19 EGO59773.1 - 2.7e-11 43.1 0.0 0.00019 21.2 0.0 2.8 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGO59773.1 - 0.00032 20.7 0.0 0.00071 19.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 ADH_N PF08240.7 EGO59774.1 - 1.9e-26 91.9 2.0 3.5e-26 91.0 1.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO59774.1 - 4.1e-16 58.6 0.2 7.3e-12 44.9 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGO59774.1 - 0.0066 15.8 0.2 0.016 14.6 0.2 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EGO59774.1 - 0.038 13.6 0.4 0.065 12.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NADH_4Fe-4S PF10589.4 EGO59774.1 - 0.071 12.2 3.6 0.14 11.3 2.5 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region NAD_binding_8 PF13450.1 EGO59774.1 - 0.094 12.7 0.1 0.3 11.1 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 EGO59774.1 - 0.18 11.5 0.9 0.36 10.6 0.6 1.4 1 0 0 1 1 1 0 ThiF family Avl9 PF09794.4 EGO59775.1 - 4e-143 476.4 0.0 5.5e-143 476.0 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 EGO59775.1 - 1.7e-07 30.7 1.0 1.4e-06 27.8 0.0 2.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 EGO59775.1 - 1.1e-06 28.2 0.0 0.00038 20.1 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis LAT PF15234.1 EGO59775.1 - 0.024 14.1 3.4 0.09 12.2 2.3 2.0 2 0 0 2 2 2 0 Linker for activation of T-cells Pkinase PF00069.20 EGO59776.1 - 3.4e-73 245.9 0.0 4.3e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO59776.1 - 8e-32 110.3 0.0 1.1e-31 109.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGO59776.1 - 8.2e-06 25.0 0.0 2.8e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGO59776.1 - 0.00027 20.7 0.1 0.0013 18.5 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGO59776.1 - 0.00032 19.7 0.0 0.026 13.4 0.0 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.17 EGO59776.1 - 0.023 14.0 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Phosphorylase PF00343.15 EGO59779.1 - 0 1078.5 0.2 0 1078.3 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 EGO59779.1 - 0.1 12.2 0.1 0.31 10.7 0.0 1.8 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Fibroin_P25 PF07294.6 EGO59780.1 - 0.12 11.8 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Fibroin P25 NODP PF07684.7 EGO59780.1 - 0.49 10.0 2.4 0.8 9.3 1.6 1.3 1 0 0 1 1 1 0 NOTCH protein Ribonuclease_T2 PF00445.13 EGO59781.1 - 9.9e-19 67.6 0.0 3.1e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease T2 family FAD_binding_4 PF01565.18 EGO59781.1 - 3.8e-13 49.1 0.0 7.4e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGO59781.1 - 1.9e-06 27.6 0.0 4.8e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like GMC_oxred_C PF05199.8 EGO59782.1 - 3.2e-13 50.1 0.2 7.1e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Imm22 PF15592.1 EGO59782.1 - 0.079 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 22 CHAD PF05235.9 EGO59783.1 - 0.055 13.0 0.7 0.087 12.3 0.5 1.3 1 0 0 1 1 1 0 CHAD domain Ank_2 PF12796.2 EGO59784.1 - 2.9e-42 142.8 1.1 6.8e-11 42.3 0.1 6.8 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO59784.1 - 1.6e-33 114.4 6.8 6.9e-07 29.6 0.1 8.5 8 2 2 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.25 EGO59784.1 - 6.2e-32 107.8 11.5 0.00025 20.6 0.1 13.0 13 0 0 13 13 13 8 Ankyrin repeat Ank_3 PF13606.1 EGO59784.1 - 1.4e-23 80.5 0.8 0.0025 17.9 0.0 11.9 12 0 0 12 12 12 5 Ankyrin repeat Ank_5 PF13857.1 EGO59784.1 - 1.3e-21 76.1 12.8 2.7e-06 27.4 0.1 8.7 6 3 2 8 8 8 5 Ankyrin repeats (many copies) DNA_pol_A_exo1 PF01612.15 EGO59785.1 - 5.3e-08 32.5 0.0 7.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease NAD_binding_8 PF13450.1 EGO59785.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ank_2 PF12796.2 EGO59786.1 - 2e-09 37.6 0.0 2.1e-08 34.3 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGO59786.1 - 4.8e-07 29.2 0.1 6.5e-05 22.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EGO59786.1 - 2e-06 27.8 0.0 2.2e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO59786.1 - 2.2e-05 24.2 0.0 0.005 16.9 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EGO59786.1 - 3.2e-05 24.3 0.0 0.0012 19.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) GATA PF00320.22 EGO59788.1 - 1.7e-14 52.8 2.2 1.7e-14 52.8 1.5 1.9 2 0 0 2 2 2 1 GATA zinc finger DUF342 PF03961.8 EGO59788.1 - 0.028 12.8 6.6 0.046 12.1 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4164 PF13747.1 EGO59788.1 - 0.24 11.5 10.0 0.6 10.2 6.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) PilJ PF13675.1 EGO59788.1 - 0.47 10.7 9.9 0.036 14.3 2.4 2.3 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4407 PF14362.1 EGO59788.1 - 1.9 7.3 9.2 4.8 6.0 6.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) KH_1 PF00013.24 EGO59789.1 - 0.0044 16.6 0.1 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 KH domain KH_4 PF13083.1 EGO59789.1 - 0.037 13.6 0.1 0.091 12.4 0.1 1.6 1 0 0 1 1 1 0 KH domain ADH_zinc_N PF00107.21 EGO59790.1 - 9.4e-23 80.1 0.3 1.6e-22 79.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO59790.1 - 9.2e-09 36.2 0.2 2e-08 35.1 0.1 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO59790.1 - 7.3e-05 22.4 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EGO59790.1 - 0.00085 19.3 0.3 0.028 14.4 0.1 2.4 2 1 0 2 2 2 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 EGO59790.1 - 0.0073 15.8 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SWIM PF04434.12 EGO59791.1 - 0.065 12.7 4.2 0.17 11.3 2.9 1.7 1 0 0 1 1 1 0 SWIM zinc finger Ribosomal_L34e PF01199.13 EGO59791.1 - 0.12 12.6 0.5 0.48 10.6 0.0 2.1 2 1 0 2 2 2 0 Ribosomal protein L34e Lactamase_B PF00753.22 EGO59792.1 - 4.3e-17 62.3 0.2 6.8e-17 61.7 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGO59792.1 - 0.026 14.0 0.1 0.036 13.6 0.1 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain PDDEXK_1 PF12705.2 EGO59792.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Sulf_transp PF04143.9 EGO59793.1 - 8.2e-14 51.3 40.7 5.2e-08 32.7 8.7 4.3 2 2 2 4 4 4 2 Sulphur transport Prok-RING_2 PF14445.1 EGO59794.1 - 0.053 13.4 6.4 0.12 12.3 4.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 DUF241 PF03087.9 EGO59794.1 - 1.1 8.6 8.4 1.6 8.1 5.8 1.2 1 0 0 1 1 1 0 Arabidopsis protein of unknown function DUF3979 PF13141.1 EGO59796.1 - 0.005 16.7 0.2 0.0084 15.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3979) DUF500 PF04366.7 EGO59798.1 - 9e-32 109.1 0.0 1.4e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) UPF0114 PF03350.11 EGO59799.1 - 0.052 13.4 0.0 0.056 13.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 LRR_4 PF12799.2 EGO59800.1 - 7.5e-05 22.2 6.8 1.5 8.4 0.0 5.3 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) F-box PF00646.28 EGO59800.1 - 0.0018 17.8 2.0 0.0055 16.3 0.1 2.8 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EGO59800.1 - 0.0059 16.2 1.1 0.027 14.1 0.0 2.6 3 0 0 3 3 3 1 F-box-like F-box-like_2 PF13013.1 EGO59800.1 - 0.0065 16.1 1.4 0.14 11.9 0.0 2.7 2 1 0 2 2 2 1 F-box-like domain LRR_8 PF13855.1 EGO59800.1 - 0.014 15.0 2.6 5.1 6.9 0.0 4.8 6 0 0 6 6 6 0 Leucine rich repeat IBR PF01485.16 EGO59801.1 - 2.1e-05 24.3 9.0 2.1e-05 24.3 6.3 5.0 4 2 0 5 5 5 2 IBR domain Actin PF00022.14 EGO59802.1 - 7.6e-15 54.2 0.0 1.6e-12 46.6 0.0 2.6 3 0 0 3 3 3 2 Actin SAP PF02037.22 EGO59803.1 - 1.2e-07 31.0 0.0 3.1e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 SAP domain EMP24_GP25L PF01105.19 EGO59803.1 - 0.017 14.8 0.6 0.017 14.8 0.4 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4011 PF13195.1 EGO59803.1 - 0.74 9.8 13.0 3.7 7.5 4.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4011) SprA-related PF12118.3 EGO59803.1 - 0.88 8.8 31.4 0.013 14.8 13.2 2.1 2 0 0 2 2 2 0 SprA-related family BAF1_ABF1 PF04684.8 EGO59803.1 - 1.9 7.2 14.2 3.6 6.3 9.9 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor OmpH PF03938.9 EGO59803.1 - 4.5 7.1 28.7 0.73 9.7 13.4 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PHD PF00628.24 EGO59803.1 - 5.3 6.8 8.3 11 5.8 5.8 1.6 1 0 0 1 1 1 0 PHD-finger PHD PF00628.24 EGO59804.1 - 0.011 15.4 3.8 0.018 14.7 2.6 1.4 1 0 0 1 1 1 0 PHD-finger CDC45 PF02724.9 EGO59804.1 - 0.038 12.0 1.8 0.06 11.3 1.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Dodecin PF07311.7 EGO59804.1 - 0.076 13.0 0.2 0.2 11.7 0.1 1.7 2 0 0 2 2 2 0 Dodecin Nucleoplasmin PF03066.10 EGO59804.1 - 0.95 8.9 5.2 1.7 8.1 3.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin zf-C3HC4_3 PF13920.1 EGO59806.1 - 0.00089 18.8 5.4 0.0021 17.7 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EGO59806.1 - 0.0062 16.1 5.9 0.012 15.2 4.1 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.1 EGO59806.1 - 0.019 14.7 6.4 0.041 13.7 4.4 1.6 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.2 EGO59806.1 - 0.08 13.0 8.4 0.97 9.5 5.5 2.4 1 1 1 2 2 2 0 RING-H2 zinc finger C1_1 PF00130.17 EGO59806.1 - 0.16 11.7 7.1 0.04 13.6 2.5 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 EGO59806.1 - 0.16 12.0 6.7 0.41 10.7 4.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO59806.1 - 0.48 10.1 6.9 1 9.1 4.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain FemAB PF02388.11 EGO59807.1 - 0.18 10.4 6.1 0.32 9.6 4.3 1.3 1 0 0 1 1 1 0 FemAB family zf-C3HC4_2 PF13923.1 EGO59807.1 - 0.87 9.6 7.5 1.9 8.5 5.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_2 PF03107.11 EGO59807.1 - 1 9.5 4.5 1.8 8.7 3.1 1.4 1 0 0 1 1 1 0 C1 domain FYVE PF01363.16 EGO59807.1 - 2.8 7.8 12.6 0.23 11.3 5.2 2.0 2 1 0 2 2 2 0 FYVE zinc finger PHD PF00628.24 EGO59807.1 - 3.7 7.3 8.4 9 6.0 5.8 1.7 1 0 0 1 1 1 0 PHD-finger PHD PF00628.24 EGO59808.1 - 0.0018 17.9 10.1 0.0032 17.1 7.0 1.4 1 0 0 1 1 1 1 PHD-finger CAF-1_p150 PF11600.3 EGO59808.1 - 0.0026 17.1 14.0 0.0044 16.4 9.7 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal HemX PF04375.9 EGO59808.1 - 0.022 13.3 1.4 0.033 12.7 1.0 1.2 1 0 0 1 1 1 0 HemX NCD2 PF04905.8 EGO59808.1 - 0.06 13.1 5.3 0.12 12.1 3.7 1.5 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) Spatacsin_C PF14649.1 EGO59808.1 - 0.086 11.7 3.6 0.13 11.1 2.5 1.1 1 0 0 1 1 1 0 Spatacsin C-terminus Ax_dynein_light PF10211.4 EGO59808.1 - 0.19 11.5 12.7 0.33 10.7 8.8 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain OmpH PF03938.9 EGO59808.1 - 0.21 11.5 4.9 0.35 10.8 3.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) C1_1 PF00130.17 EGO59808.1 - 0.73 9.6 11.0 0.078 12.7 3.9 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Fzo_mitofusin PF04799.8 EGO59808.1 - 1.1 8.6 5.7 1.9 7.8 3.9 1.3 1 0 0 1 1 1 0 fzo-like conserved region zf-RING_2 PF13639.1 EGO59808.1 - 1.8 8.4 9.0 3.5 7.5 6.3 1.5 1 0 0 1 1 1 0 Ring finger domain ATP-synt_B PF00430.13 EGO59808.1 - 3.9 7.2 10.8 6.8 6.5 7.5 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF4337 PF14235.1 EGO59808.1 - 5.9 6.6 8.0 10 5.8 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Mitofilin PF09731.4 EGO59808.1 - 7 5.1 16.4 9.7 4.7 11.4 1.3 1 1 0 1 1 1 0 Mitochondrial inner membrane protein KIX PF02172.11 EGO59810.1 - 0.0081 16.1 0.8 0.017 15.1 0.6 1.5 1 0 0 1 1 1 1 KIX domain APG6 PF04111.7 EGO59810.1 - 0.025 13.6 1.3 0.036 13.1 0.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1177 PF06675.6 EGO59810.1 - 0.073 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) FlxA PF14282.1 EGO59810.1 - 0.087 12.7 1.9 0.26 11.2 1.3 1.8 1 0 0 1 1 1 0 FlxA-like protein PMC2NT PF08066.7 EGO59810.1 - 0.16 12.2 1.2 0.7 10.2 0.7 2.1 2 0 0 2 2 2 0 PMC2NT (NUC016) domain DUF2721 PF11026.3 EGO59810.1 - 0.33 10.5 3.3 0.57 9.8 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) adh_short PF00106.20 EGO59815.1 - 6.7e-61 205.0 5.6 3.2e-30 105.2 0.1 2.4 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EGO59815.1 - 3.1e-34 117.0 0.0 6.2e-34 116.0 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EGO59815.1 - 2.7e-29 102.1 0.6 2.3e-13 50.1 0.1 2.3 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 EGO59815.1 - 2.4e-05 23.9 0.8 0.0051 16.2 0.1 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EGO59815.1 - 0.00085 18.4 0.8 0.0091 15.0 0.2 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SRP54 PF00448.17 EGO59816.1 - 1.3e-07 31.2 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_17 PF13207.1 EGO59816.1 - 6.7e-07 30.1 0.1 7e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGO59816.1 - 6.6e-05 23.2 0.1 0.0002 21.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGO59816.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ArgK PF03308.11 EGO59816.1 - 0.00036 19.3 0.0 0.00057 18.7 0.0 1.2 1 0 0 1 1 1 1 ArgK protein cobW PF02492.14 EGO59816.1 - 0.00051 19.5 0.1 0.0008 18.8 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_31 PF13614.1 EGO59816.1 - 0.00064 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EGO59816.1 - 0.0007 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain NACHT PF05729.7 EGO59816.1 - 0.0014 18.2 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 EGO59816.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EGO59816.1 - 0.002 18.2 0.0 0.0048 17.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EGO59816.1 - 0.003 17.2 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 EGO59816.1 - 0.0046 16.5 0.1 0.012 15.2 0.0 1.7 2 0 0 2 2 1 1 Uncharacterised P-loop hydrolase UPF0079 Thymidylate_kin PF02223.12 EGO59816.1 - 0.0087 15.4 0.7 0.06 12.7 0.0 2.4 3 0 0 3 3 3 1 Thymidylate kinase Zeta_toxin PF06414.7 EGO59816.1 - 0.0088 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin NTPase_1 PF03266.10 EGO59816.1 - 0.0099 15.5 0.2 0.016 14.9 0.1 1.3 1 0 0 1 1 1 1 NTPase ABC_tran PF00005.22 EGO59816.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EGO59816.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EGO59816.1 - 0.024 14.1 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 EGO59816.1 - 0.027 14.6 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGO59816.1 - 0.028 14.1 0.0 0.088 12.5 0.0 1.8 2 0 0 2 2 1 0 Part of AAA domain NB-ARC PF00931.17 EGO59816.1 - 0.037 12.9 0.0 0.061 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.12 EGO59816.1 - 0.04 13.4 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 EGO59816.1 - 0.042 13.8 0.1 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain LpxK PF02606.9 EGO59816.1 - 0.05 12.5 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase CbiA PF01656.18 EGO59816.1 - 0.05 13.0 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EGO59816.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase Arch_ATPase PF01637.13 EGO59816.1 - 0.067 12.8 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 EGO59816.1 - 0.069 13.3 0.0 0.18 12.0 0.0 1.8 1 1 0 1 1 1 0 RNA helicase KTI12 PF08433.5 EGO59816.1 - 0.081 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.9 EGO59816.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EGO59816.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ECM11 PF15463.1 EGO59817.1 - 5.4e-41 140.1 7.8 5.4e-41 140.1 5.4 2.8 3 0 0 3 3 3 1 Extracellular mutant protein 11 ParA PF10609.4 EGO59818.1 - 1.5e-34 117.7 0.0 2.6e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGO59818.1 - 9.3e-14 51.2 0.0 1.4e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EGO59818.1 - 8.2e-06 25.0 0.0 0.00068 18.7 0.1 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 EGO59818.1 - 1.8e-05 24.7 0.0 4.3e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 EGO59818.1 - 0.0023 17.0 0.0 0.0062 15.6 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 EGO59818.1 - 0.0043 16.4 0.1 0.0077 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGO59818.1 - 0.0083 15.3 0.1 0.015 14.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SRP54 PF00448.17 EGO59818.1 - 0.022 14.1 0.0 0.038 13.4 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EGO59818.1 - 0.035 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EGO59818.1 - 0.053 12.2 0.0 0.072 11.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EGO59818.1 - 0.06 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EGO59818.1 - 0.06 13.0 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EGO59818.1 - 0.083 11.7 0.2 0.12 11.2 0.2 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein Fer4_NifH PF00142.13 EGO59818.1 - 0.085 12.0 0.0 0.36 9.9 0.1 1.8 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_19 PF13245.1 EGO59818.1 - 0.098 12.4 0.2 0.97 9.2 0.1 2.3 2 0 0 2 2 2 0 Part of AAA domain VirE PF05272.6 EGO59818.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E AAA_26 PF13500.1 EGO59818.1 - 0.15 11.6 0.1 15 5.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ras PF00071.17 EGO59818.1 - 0.16 11.3 0.1 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Ras family MoCF_biosynth PF00994.19 EGO59819.1 - 1.1e-29 102.6 0.0 1.9e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.17 EGO59820.1 - 5.4e-58 194.9 0.1 6.6e-58 194.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO59820.1 - 4.5e-17 62.6 0.0 7e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO59820.1 - 2.3e-09 36.7 0.0 2.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGO59820.1 - 2.5e-07 30.3 0.1 1.1e-06 28.2 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGO59820.1 - 0.0061 15.7 0.0 0.0073 15.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGO59820.1 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGO59820.1 - 0.056 12.6 0.0 0.26 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF3783 PF12646.2 EGO59820.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) Kelch_5 PF13854.1 EGO59822.1 - 5.2e-16 58.2 1.8 6.8e-13 48.2 0.2 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 EGO59822.1 - 0.00013 21.9 3.2 0.066 13.4 0.4 3.9 2 1 1 3 3 3 1 Kelch motif Kelch_3 PF13415.1 EGO59822.1 - 0.00026 21.0 3.3 0.00096 19.2 0.1 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 EGO59822.1 - 0.00089 18.7 3.8 0.69 9.5 0.0 3.8 3 0 0 3 3 3 1 Kelch motif DUF4381 PF14316.1 EGO59822.1 - 0.5 10.4 2.0 0.99 9.5 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Cys_rich_CPXG PF14255.1 EGO59823.1 - 0.03 14.1 1.9 0.57 10.0 0.1 2.5 2 0 0 2 2 2 0 Cysteine-rich CPXCG TrkA_N PF02254.13 EGO59824.1 - 0.35 10.8 3.8 0.33 10.9 1.6 1.7 1 1 0 1 1 1 0 TrkA-N domain DUF3632 PF12311.3 EGO59826.1 - 0.12 12.1 12.2 2.2 8.0 8.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3632) ArfGap PF01412.13 EGO59828.1 - 2.2e-36 124.1 1.0 5.2e-36 122.9 0.1 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf TIM21 PF08294.6 EGO59829.1 - 3.6e-52 175.8 0.0 4.8e-52 175.4 0.0 1.2 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EGO59829.1 - 2.9e-05 23.5 0.0 0.00015 21.2 0.0 2.1 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 FAD-oxidase_C PF02913.14 EGO59829.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Bromodomain PF00439.20 EGO59831.1 - 6.3e-19 67.6 0.0 1.2e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain BTB PF00651.26 EGO59831.1 - 3e-06 27.1 0.0 5.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain KaiC PF06745.8 EGO59832.1 - 9e-06 24.9 0.0 1.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 EGO59832.1 - 1.1e-05 24.9 0.0 2.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EGO59832.1 - 0.0002 20.5 0.0 0.00026 20.1 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein DnaB_C PF03796.10 EGO59832.1 - 0.00024 20.1 0.0 0.00034 19.5 0.0 1.1 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.12 EGO59832.1 - 0.03 13.7 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein zf-H2C2_2 PF13465.1 EGO59834.1 - 7.1e-08 32.3 25.6 4e-06 26.8 2.4 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EGO59834.1 - 7.3e-08 32.3 13.6 0.0012 19.0 2.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO59834.1 - 4.8e-06 26.5 12.1 0.0071 16.5 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2225 PF09986.4 EGO59834.1 - 0.38 10.1 0.7 0.84 9.0 0.5 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.3 EGO59834.1 - 0.41 10.8 4.1 0.27 11.4 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EGO59834.1 - 0.72 9.8 3.7 3.4 7.7 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger FPN1 PF06963.7 EGO59836.1 - 5.7e-121 403.9 11.2 6.8e-121 403.6 7.8 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Amidase PF01425.16 EGO59837.1 - 3.9e-91 306.1 0.0 4.8e-91 305.8 0.0 1.1 1 0 0 1 1 1 1 Amidase Glyco_hydro_76 PF03663.9 EGO59842.1 - 1.3e-127 426.2 9.9 1.5e-127 426.0 6.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Phage_sheath_1 PF04984.9 EGO59842.1 - 0.032 12.6 0.0 0.034 12.5 0.0 1.2 1 0 0 1 1 1 0 Phage tail sheath protein DUF4329 PF14220.1 EGO59844.1 - 0.059 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) MscL PF01741.13 EGO59845.1 - 1.7e-16 60.5 0.1 2.5e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL NMO PF03060.10 EGO59847.1 - 6.3e-71 239.2 0.3 7.8e-71 238.9 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGO59847.1 - 2.7e-09 36.3 0.1 4.3e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGO59847.1 - 2.8e-06 26.4 1.9 4.2e-06 25.8 1.3 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EGO59847.1 - 0.003 16.5 0.3 0.0057 15.6 0.2 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EGO59847.1 - 0.0032 16.4 1.2 0.0053 15.7 0.8 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NanE PF04131.9 EGO59847.1 - 0.01 14.8 0.4 0.026 13.4 0.1 1.9 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Pterin_bind PF00809.17 EGO59848.1 - 1.6e-61 207.3 0.0 3.5e-61 206.2 0.0 1.6 2 0 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 EGO59848.1 - 1.1e-38 131.8 0.0 1.6e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Tachystatin_B PF11478.3 EGO59850.1 - 0.33 10.6 3.3 0.41 10.4 1.1 1.9 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B EFF-AFF PF14884.1 EGO59851.1 - 7.9 4.4 9.4 9 4.2 6.5 1.0 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen BNR_2 PF13088.1 EGO59852.1 - 1.6e-05 24.3 0.4 0.011 15.0 0.1 2.3 1 1 1 2 2 2 2 BNR repeat-like domain Glyco_hydro_3 PF00933.16 EGO59853.1 - 5e-62 209.5 0.0 6.8e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO59853.1 - 2e-40 138.7 0.3 3.2e-40 138.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGO59853.1 - 5.5e-07 29.4 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain LRR_6 PF13516.1 EGO59854.1 - 1.6 9.0 3.3 57 4.2 0.2 3.8 4 0 0 4 4 4 0 Leucine Rich repeat Phytochelatin_C PF09328.5 EGO59855.1 - 0.15 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) Maf_N PF08383.6 EGO59858.1 - 0.0081 15.6 0.4 0.14 11.6 0.0 2.2 2 0 0 2 2 2 1 Maf N-terminal region NDT80_PhoG PF05224.7 EGO59859.1 - 1.5e-54 184.7 0.3 6.3e-54 182.7 0.0 1.9 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Mito_fiss_reg PF05308.6 EGO59862.1 - 0.14 11.4 6.4 0.2 10.9 4.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Med3 PF11593.3 EGO59862.1 - 0.85 8.7 9.1 1.1 8.4 6.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CAP_N PF01213.14 EGO59862.1 - 1.1 8.4 6.0 1.5 8.0 4.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal LysM PF01476.15 EGO59863.1 - 1.2e-37 127.5 10.7 5.1e-09 35.8 0.0 5.2 5 0 0 5 5 5 5 LysM domain UPF0203 PF05254.7 EGO59863.1 - 0.0053 16.5 8.5 3.1 7.7 0.1 4.5 4 0 0 4 4 4 3 Uncharacterised protein family (UPF0203) HTH_23 PF13384.1 EGO59863.1 - 0.015 14.9 0.0 45 3.8 0.0 3.9 4 0 0 4 4 4 0 Homeodomain-like domain DUF521 PF04412.8 EGO59864.1 - 0.063 11.8 0.0 0.089 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Glyco_hydro_18 PF00704.23 EGO59865.1 - 1.1e-40 140.2 1.4 1.8e-40 139.4 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.1 EGO59865.1 - 8.3e-32 108.9 2.1 3.8e-31 106.8 1.5 2.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.15 EGO59865.1 - 4.1e-05 23.3 0.0 0.097 12.5 0.0 2.8 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 EGO59865.1 - 0.00036 20.4 3.4 0.00036 20.4 2.3 3.2 3 0 0 3 3 3 1 Chitin recognition protein Ank_2 PF12796.2 EGO59866.1 - 8.4e-35 118.9 0.8 2.4e-13 50.2 0.0 5.2 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EGO59866.1 - 3.6e-25 86.4 0.9 0.0046 16.6 0.0 8.6 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 EGO59866.1 - 1e-21 76.8 0.2 4.9e-08 33.2 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO59866.1 - 2.7e-18 64.2 0.5 0.026 14.7 0.0 8.8 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.1 EGO59866.1 - 9.2e-18 63.8 0.2 0.0013 18.9 0.0 6.4 5 2 0 5 5 5 5 Ankyrin repeats (many copies) NACHT PF05729.7 EGO59866.1 - 0.00036 20.2 0.0 0.00086 19.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 EGO59867.1 - 6.9e-11 41.5 0.1 9.3e-11 41.1 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Ran_BP1 PF00638.13 EGO59868.1 - 6.4e-11 42.3 0.3 2.5e-05 24.2 0.1 2.4 2 0 0 2 2 2 2 RanBP1 domain Daxx PF03344.10 EGO59868.1 - 4.8 5.5 27.9 1.5 7.1 2.1 2.1 2 0 0 2 2 2 0 Daxx Family CRISPR_Cse1 PF09481.5 EGO59869.1 - 0.0019 17.0 0.1 0.003 16.3 0.0 1.2 1 0 0 1 1 1 1 CRISPR-associated protein Cse1 (CRISPR_cse1) CcmD PF04995.9 EGO59869.1 - 0.14 11.9 0.2 0.5 10.1 0.1 2.0 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) zf-RING_2 PF13639.1 EGO59870.1 - 1.2e-15 57.0 6.4 1.2e-15 57.0 4.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGO59870.1 - 1.5e-10 40.5 6.8 1.7e-09 37.1 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGO59870.1 - 1.7e-08 34.4 2.7 1.7e-08 34.4 1.9 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGO59870.1 - 1.5e-07 31.2 6.9 1.5e-07 31.2 4.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO59870.1 - 4.3e-06 26.3 4.1 4.3e-06 26.3 2.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGO59870.1 - 1.2e-05 24.8 6.4 1.2e-05 24.8 4.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EGO59870.1 - 0.0018 17.7 3.6 0.0018 17.7 2.5 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EGO59870.1 - 0.0033 17.2 1.8 0.0091 15.8 1.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.9 EGO59870.1 - 0.0033 16.8 1.6 0.0079 15.6 1.1 1.7 1 0 0 1 1 1 1 P-11 zinc finger zf-RING_3 PF14369.1 EGO59870.1 - 0.011 15.6 5.1 0.011 15.6 3.6 2.5 2 0 0 2 2 2 0 zinc-finger DUF1572 PF07609.6 EGO59870.1 - 0.024 14.1 0.8 0.044 13.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) HypA PF01155.14 EGO59870.1 - 0.08 12.6 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Baculo_RING PF05883.6 EGO59870.1 - 0.11 12.3 0.8 0.29 10.9 0.6 1.7 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain RINGv PF12906.2 EGO59870.1 - 0.11 12.5 7.7 0.28 11.2 5.3 1.7 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 EGO59870.1 - 0.97 9.1 14.0 0.077 12.6 3.8 2.6 2 1 0 2 2 2 0 PHD-finger zf-RING_4 PF14570.1 EGO59870.1 - 6.1 6.5 13.5 0.77 9.3 2.9 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Fis1_TPR_C PF14853.1 EGO59871.1 - 3.1e-26 90.9 2.1 4.4e-26 90.5 1.5 1.2 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EGO59871.1 - 7e-18 63.6 0.0 1.2e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EGO59871.1 - 0.0036 17.1 3.7 0.0084 15.9 2.5 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO59871.1 - 0.0065 17.1 1.0 0.012 16.2 0.7 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGO59871.1 - 0.046 14.2 0.7 0.099 13.1 0.5 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGO59871.1 - 0.051 13.9 0.3 0.092 13.0 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.6 EGO59872.1 - 8.7e-43 144.7 2.8 2e-40 137.1 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.15 EGO59872.1 - 0.0017 18.0 8.5 0.016 14.9 1.0 2.2 2 0 0 2 2 2 1 Prefoldin subunit Reo_sigmaC PF04582.7 EGO59872.1 - 0.014 14.5 4.7 0.019 14.1 3.3 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 EGO59872.1 - 0.015 13.2 1.1 0.02 12.7 0.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.6 EGO59872.1 - 0.016 15.0 4.7 1 9.3 0.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Hemerythrin PF01814.18 EGO59872.1 - 0.02 15.0 0.6 0.03 14.4 0.4 1.3 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain AAA_13 PF13166.1 EGO59872.1 - 0.02 13.3 1.4 0.025 13.0 0.9 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EGO59872.1 - 0.043 12.8 7.7 0.063 12.3 5.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 PLAC9 PF15205.1 EGO59872.1 - 0.051 13.8 0.1 0.099 12.9 0.1 1.5 1 0 0 1 1 1 0 Placenta-specific protein 9 HR1 PF02185.11 EGO59872.1 - 0.06 13.0 10.7 0.18 11.5 1.2 2.4 2 0 0 2 2 2 0 Hr1 repeat DUF4613 PF15390.1 EGO59872.1 - 0.067 11.3 4.9 0.084 11.0 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) CCDC32 PF14989.1 EGO59872.1 - 0.068 13.0 4.5 0.12 12.1 3.1 1.6 1 1 0 1 1 1 0 Coiled-coil domain containing 32 FliJ PF02050.11 EGO59872.1 - 0.076 13.0 10.7 0.12 12.4 7.4 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein MAD PF05557.8 EGO59872.1 - 0.085 10.9 10.6 0.15 10.0 7.4 1.3 1 1 0 1 1 1 0 Mitotic checkpoint protein SlyX PF04102.7 EGO59872.1 - 0.096 13.0 7.1 0.46 10.8 0.3 2.8 2 1 1 3 3 3 0 SlyX TraC PF07820.7 EGO59872.1 - 0.11 12.6 2.0 0.2 11.8 1.0 1.9 1 1 0 1 1 1 0 TraC-like protein FlxA PF14282.1 EGO59872.1 - 0.26 11.2 13.5 0.051 13.5 3.1 2.4 1 1 1 2 2 2 0 FlxA-like protein DUF724 PF05266.9 EGO59872.1 - 0.28 10.7 4.4 0.42 10.1 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Noelin-1 PF12308.3 EGO59872.1 - 0.29 10.9 3.7 0.27 11.0 0.3 2.1 2 0 0 2 2 2 0 Neurogenesis glycoprotein Sas10_Utp3 PF04000.10 EGO59872.1 - 0.31 11.2 4.1 12 6.1 1.0 2.6 2 1 0 2 2 2 0 Sas10/Utp3/C1D family Streptin-Immun PF11083.3 EGO59872.1 - 0.41 10.6 2.9 1.1 9.3 0.1 2.2 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein DUF3073 PF11273.3 EGO59872.1 - 0.7 10.4 4.2 0.32 11.5 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3073) FUSC PF04632.7 EGO59872.1 - 0.8 8.0 3.2 0.95 7.8 2.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin PF00804.20 EGO59872.1 - 0.83 9.8 7.2 1.8 8.7 4.8 1.8 1 1 1 2 2 2 0 Syntaxin Viral_P18 PF04521.8 EGO59872.1 - 0.84 9.0 10.9 0.41 10.0 1.7 2.3 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Exonuc_VII_L PF02601.10 EGO59872.1 - 0.9 8.6 6.4 1.2 8.2 4.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Allexi_40kDa PF05549.6 EGO59872.1 - 0.99 8.6 6.7 3.9 6.6 4.6 1.8 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF4164 PF13747.1 EGO59872.1 - 1.1 9.4 10.4 1.2 9.3 5.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) PEP-utilisers_N PF05524.8 EGO59872.1 - 1.1 9.1 7.9 1.1 9.1 0.8 2.4 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal TMF_DNA_bd PF12329.3 EGO59872.1 - 1.4 8.7 11.3 0.23 11.2 2.1 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 EGO59872.1 - 1.9 8.8 6.7 10 6.4 0.5 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.7 EGO59872.1 - 2.5 7.8 13.0 5.9 6.6 8.5 1.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein XhlA PF10779.4 EGO59872.1 - 2.8 7.9 5.5 2.5 8.0 0.9 2.3 1 1 1 2 2 2 0 Haemolysin XhlA IncA PF04156.9 EGO59872.1 - 3.2 7.3 16.4 8.7 5.8 11.4 1.6 1 1 0 1 1 1 0 IncA protein DUF948 PF06103.6 EGO59872.1 - 4 7.3 6.1 6 6.8 0.7 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF972 PF06156.8 EGO59872.1 - 5.2 7.4 6.8 1.6e+02 2.6 4.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) EAP30 PF04157.11 EGO59872.1 - 6.4 5.8 10.4 0.88 8.6 2.8 2.0 1 1 1 2 2 2 0 EAP30/Vps36 family TBPIP PF07106.8 EGO59872.1 - 6.6 6.2 8.2 52 3.3 5.8 2.0 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin PF02996.12 EGO59872.1 - 6.7 6.3 9.5 9.2 5.9 1.3 2.3 1 1 0 2 2 2 0 Prefoldin subunit ADIP PF11559.3 EGO59872.1 - 8.2 6.3 15.7 6.4 6.6 7.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TatD_DNase PF01026.16 EGO59875.1 - 3.6e-31 108.2 0.0 8.2e-31 107.1 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase Fungal_trans PF04082.13 EGO59876.1 - 1.8e-22 79.4 0.4 2.9e-22 78.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zip PF02535.17 EGO59876.1 - 0.055 12.4 7.5 0.14 11.1 5.2 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter 60KD_IMP PF02096.15 EGO59876.1 - 0.068 12.8 0.3 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein SelP_N PF04592.9 EGO59876.1 - 2.2 7.5 13.9 4.1 6.7 9.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.4 EGO59876.1 - 4.8 5.3 16.2 7.3 4.7 11.2 1.2 1 0 0 1 1 1 0 Transmembrane protein Pyridox_oxase_2 PF12766.2 EGO59879.1 - 3.7e-16 59.2 0.0 4.5e-15 55.7 0.0 2.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RNA_pol_Rpb5_C PF01191.14 EGO59880.1 - 2.2e-35 120.1 1.2 2.4e-35 119.9 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EGO59880.1 - 2.5e-32 111.1 0.0 4.4e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EGO59880.1 - 0.0037 17.0 0.0 0.0085 15.8 0.0 1.6 1 0 0 1 1 1 1 Restriction endonuclease Occludin_ELL PF07303.8 EGO59881.1 - 0.029 15.1 9.4 0.029 15.1 6.5 5.2 3 2 2 5 5 5 0 Occludin homology domain Baculo_PEP_C PF04513.7 EGO59881.1 - 1.1 9.0 10.2 4.4 7.1 0.6 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GTP_cyclohydro2 PF00925.15 EGO59882.1 - 0.26 10.4 2.2 4.2 6.5 0.1 2.1 1 1 0 2 2 2 0 GTP cyclohydrolase II GTP1_OBG PF01018.17 EGO59883.1 - 5.3e-39 133.3 1.5 6.8e-29 100.5 2.1 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EGO59883.1 - 2.1e-22 79.2 0.0 3.1e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO59883.1 - 9.3e-07 28.2 0.1 2.6e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 EGO59883.1 - 0.024 13.3 0.0 0.064 12.0 0.0 1.6 1 0 0 1 1 1 0 ArgK protein ABC_tran PF00005.22 EGO59883.1 - 0.033 14.4 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EGO59883.1 - 0.043 13.8 0.1 8.1 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Arf PF00025.16 EGO59883.1 - 0.08 12.1 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGO59883.1 - 0.19 11.1 0.0 8.3 5.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Nol1_Nop2_Fmu PF01189.12 EGO59884.1 - 3e-36 125.2 0.0 1.3e-24 87.0 0.0 4.4 3 1 1 4 4 4 4 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EGO59884.1 - 0.003 17.5 0.0 0.006 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGO59884.1 - 0.2 11.6 0.0 0.5 10.3 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase WD40 PF00400.27 EGO59885.1 - 1.1e-19 69.5 17.2 5.3e-08 32.4 0.2 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat RNA_pol_I_TF PF04090.7 EGO59886.1 - 2.1e-06 27.1 0.0 0.00057 19.2 0.0 2.5 2 1 0 2 2 2 2 RNA polymerase I specific initiation factor DUF1952 PF09189.5 EGO59886.1 - 0.0062 16.1 0.0 0.019 14.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1952) MRP-S33 PF08293.6 EGO59886.1 - 0.019 14.9 2.0 0.32 10.9 0.2 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit S27 ETC_C1_NDUFA5 PF04716.9 EGO59887.1 - 8.7e-24 82.8 0.5 1.9e-23 81.7 0.3 1.6 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2452 PF10504.4 EGO59887.1 - 0.054 12.7 0.0 0.13 11.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2452) Mo-co_dimer PF03404.11 EGO59888.1 - 9.3e-57 190.2 0.0 1.9e-56 189.3 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EGO59888.1 - 4.8e-49 166.0 0.1 8.2e-49 165.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 EGO59888.1 - 1.1e-28 99.2 0.0 2e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGO59888.1 - 1.7e-25 89.6 0.1 4.1e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EGO59888.1 - 3.3e-25 87.6 0.0 5.9e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EGO59888.1 - 0.0009 19.1 0.8 0.081 12.8 0.0 2.8 3 0 0 3 3 3 1 Ferric reductase NAD binding domain Spc97_Spc98 PF04130.8 EGO59889.1 - 3.2e-129 431.7 3.2 5.2e-129 431.0 2.2 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family Proteasome PF00227.21 EGO59890.1 - 7.6e-57 191.6 0.2 9.5e-57 191.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGO59890.1 - 1.1e-13 50.1 0.0 2.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 EGO59890.1 - 0.025 14.2 0.1 0.5 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) Fungal_trans_2 PF11951.3 EGO59891.1 - 1.5e-17 63.3 0.7 1.2e-16 60.3 0.5 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO59891.1 - 6.7e-08 32.3 11.2 1.1e-07 31.5 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EGO59891.1 - 0.00039 19.3 2.6 0.0019 17.1 1.7 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_8 PF05148.10 EGO59892.1 - 1e-54 185.5 0.0 5.8e-52 176.4 0.0 2.6 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EGO59892.1 - 1.5e-09 38.1 0.0 1.5e-08 34.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO59892.1 - 0.00058 20.1 0.2 0.045 14.1 0.0 3.4 2 2 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO59892.1 - 0.0027 17.3 0.3 0.067 12.7 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Ribosomal_60s PF00428.14 EGO59892.1 - 0.031 14.6 3.0 0.031 14.6 2.1 5.3 2 1 3 5 5 5 0 60s Acidic ribosomal protein SAPS PF04499.10 EGO59892.1 - 0.16 10.5 2.9 0.27 9.8 2.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Methyltransf_32 PF13679.1 EGO59892.1 - 0.21 11.2 0.0 0.21 11.2 0.0 2.9 3 1 0 3 3 3 0 Methyltransferase domain Dicty_REP PF05086.7 EGO59892.1 - 0.93 7.1 11.8 1.3 6.7 8.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Menin PF05053.8 EGO59892.1 - 1.2 7.2 17.3 0.05 11.7 8.1 1.4 2 0 0 2 2 2 0 Menin Zip PF02535.17 EGO59892.1 - 6.2 5.7 4.9 57 2.5 0.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Pribosyltran PF00156.22 EGO59894.1 - 2e-14 53.4 0.4 3.4e-14 52.6 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NOGCT PF08155.6 EGO59895.1 - 2.4e-29 100.7 2.8 2.7e-29 100.6 1.0 1.8 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.9 EGO59895.1 - 2.8e-28 97.5 0.2 6.3e-28 96.4 0.1 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EGO59895.1 - 3.9e-14 52.6 0.0 8.4e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO59895.1 - 2.8e-09 36.4 0.0 5.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EGO59895.1 - 0.001 19.5 0.0 0.003 18.0 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein GDI PF00996.13 EGO59896.1 - 1.3e-186 620.2 0.0 1.6e-186 619.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EGO59896.1 - 0.012 15.5 0.0 0.22 11.5 0.1 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.8 EGO59897.1 - 3.5e-23 81.2 1.0 6e-23 80.5 0.7 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.7 EGO59897.1 - 0.18 11.0 0.5 0.31 10.2 0.3 1.3 1 0 0 1 1 1 0 Clc-like zf-H2C2_2 PF13465.1 EGO59899.1 - 2.9e-07 30.4 10.8 5e-06 26.5 0.8 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO59899.1 - 1.9e-06 27.8 13.3 0.00061 19.9 4.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EGO59899.1 - 0.00041 20.4 3.2 0.00075 19.5 2.2 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EGO59899.1 - 0.0031 17.7 15.8 0.021 15.1 4.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_Tnp_IS1595 PF12760.2 EGO59899.1 - 0.32 10.8 1.7 0.54 10.0 1.2 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C2H2_jaz PF12171.3 EGO59899.1 - 0.75 10.0 5.7 3.3 7.9 0.5 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EGO59899.1 - 1.6 8.5 8.2 0.56 10.0 0.9 2.4 2 0 0 2 2 2 0 BED zinc finger Spc97_Spc98 PF04130.8 EGO59902.1 - 8.9e-80 268.5 0.0 1.4e-79 267.8 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family Eaf7 PF07904.8 EGO59903.1 - 2.4e-18 65.8 0.0 2.4e-18 65.8 0.0 2.1 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 BSP_II PF05432.6 EGO59903.1 - 0.046 12.9 16.1 0.076 12.2 11.2 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 EGO59903.1 - 0.22 10.6 16.2 0.34 10.0 11.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 EGO59903.1 - 0.26 9.7 24.8 0.36 9.2 17.2 1.2 1 0 0 1 1 1 0 Daxx Family CDC27 PF09507.5 EGO59903.1 - 0.27 10.4 22.4 0.37 9.9 15.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.7 EGO59903.1 - 0.32 8.8 21.4 0.41 8.4 14.9 1.0 1 0 0 1 1 1 0 Nop14-like family S-antigen PF05756.6 EGO59903.1 - 0.75 9.8 5.6 1.5 8.8 3.9 1.5 1 0 0 1 1 1 0 S-antigen protein NOA36 PF06524.7 EGO59903.1 - 1.4 8.1 9.0 11 5.1 7.6 1.5 2 0 0 2 2 2 0 NOA36 protein Ilar_coat PF01787.11 EGO59903.1 - 4.3 6.8 7.2 0.16 11.5 0.3 2.0 2 1 0 2 2 2 0 Ilarvirus coat protein DASH_Ask1 PF08655.5 EGO59904.1 - 1.5e-30 104.7 0.1 2.7e-30 104.0 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 MRP-S23 PF10484.4 EGO59904.1 - 0.037 13.9 0.2 0.15 11.9 0.0 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 Rhodanese PF00581.15 EGO59905.1 - 2.8e-11 43.7 0.0 4.8e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain p450 PF00067.17 EGO59906.1 - 5.9e-52 176.7 0.0 8.3e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CENP-N PF05238.8 EGO59907.1 - 0.00033 19.8 0.8 0.00036 19.7 0.5 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like CPSF73-100_C PF11718.3 EGO59907.1 - 0.36 10.1 3.8 0.47 9.7 2.6 1.1 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Yip1 PF04893.12 EGO59908.1 - 2e-13 50.1 17.2 4.1e-13 49.2 11.9 1.5 1 1 0 1 1 1 1 Yip1 domain ubiquitin PF00240.18 EGO59909.1 - 9.8e-36 120.9 1.3 1.1e-35 120.8 0.9 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGO59909.1 - 4.2e-19 68.0 0.6 4.5e-19 67.8 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGO59909.1 - 6.8e-07 29.4 0.2 2.9e-06 27.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGO59909.1 - 0.00087 19.0 0.0 0.00096 18.8 0.0 1.0 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EGO59909.1 - 0.0012 18.7 0.1 0.0027 17.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGO59909.1 - 0.0026 17.9 0.1 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 EGO59909.1 - 0.066 13.1 0.1 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG DUF2870 PF11069.3 EGO59909.1 - 0.071 13.1 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EGO59909.1 - 0.15 10.3 1.1 1.6 6.9 0.3 1.9 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Tash_PEST PF07708.6 EGO59909.1 - 0.31 11.0 1.8 0.56 10.2 1.2 1.4 1 0 0 1 1 1 0 Tash protein PEST motif RRN7 PF11781.3 EGO59910.1 - 3.2e-07 29.7 5.8 6.4e-07 28.7 4.0 1.5 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 F-box-like_2 PF13013.1 EGO59910.1 - 0.058 13.1 0.1 0.96 9.2 0.0 2.4 2 0 0 2 2 2 0 F-box-like domain eIF-5a PF01287.15 EGO59911.1 - 3.1e-21 75.0 0.6 4.5e-21 74.5 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EGO59911.1 - 4.1e-05 23.1 0.8 7.6e-05 22.2 0.6 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EGO59911.1 - 0.0033 17.2 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.15 EGO59911.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) OB domain Vps52 PF04129.7 EGO59912.1 - 3.5e-127 425.0 0.5 4.1e-127 424.7 0.4 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EGO59912.1 - 3.8e-06 25.3 3.7 1.2e-05 23.7 2.5 1.7 1 1 0 1 1 1 1 Exocyst complex component Sec3 Mer2 PF09074.5 EGO59912.1 - 0.0019 18.1 0.0 0.0058 16.5 0.0 1.9 1 0 0 1 1 1 1 Mer2 DUF1664 PF07889.7 EGO59912.1 - 0.0096 15.7 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Filament PF00038.16 EGO59912.1 - 0.038 13.4 0.5 0.095 12.1 0.3 1.6 1 0 0 1 1 1 0 Intermediate filament protein CENP-F_leu_zip PF10473.4 EGO59912.1 - 0.1 12.4 0.8 0.6 9.9 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RabGAP-TBC PF00566.13 EGO59913.1 - 4.6e-25 88.3 0.0 6.2e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.4 EGO59914.1 - 1.1e-117 393.2 0.0 2.7e-117 391.9 0.0 1.5 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term GTP_EFTU PF00009.22 EGO59915.1 - 1.6e-33 115.7 0.0 8.2e-33 113.4 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EGO59915.1 - 5.1e-19 68.1 0.0 1.3e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EGO59915.1 - 9.1e-10 38.5 3.2 2.6e-07 30.6 0.1 3.2 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGO59915.1 - 9.4e-07 28.8 0.1 4.1e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EGO59915.1 - 0.00015 21.4 0.1 0.00086 18.9 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EGO59915.1 - 0.05 13.5 0.0 0.05 13.5 0.0 3.4 1 1 0 2 2 2 0 AAA ATPase domain Arena_glycoprot PF00798.13 EGO59915.1 - 0.12 10.7 0.0 0.25 9.6 0.0 1.4 1 0 0 1 1 1 0 Arenavirus glycoprotein HSP70 PF00012.15 EGO59916.1 - 2.6e-163 544.1 1.3 2.6e-163 544.1 0.9 1.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EGO59916.1 - 2.2e-10 39.6 0.0 1.7e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EGO59916.1 - 0.00074 19.3 1.2 2.4 8.0 0.1 3.8 2 1 0 2 2 2 2 Cell division protein FtsA Trans_reg_C PF00486.23 EGO59916.1 - 0.029 14.3 0.1 0.11 12.4 0.0 2.1 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal IncA PF04156.9 EGO59916.1 - 3.3 7.2 10.2 1.5 8.4 0.4 2.3 2 0 0 2 2 2 0 IncA protein Chitin_synth_2 PF03142.10 EGO59917.1 - 2.6e-25 88.8 4.9 3.6e-22 78.4 2.3 2.4 2 1 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EGO59917.1 - 6.8e-19 68.5 0.0 1.7e-18 67.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGO59917.1 - 1.1e-18 67.7 5.3 5.9e-18 65.2 4.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EGO59917.1 - 0.0016 18.1 0.0 2.5 7.7 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 Pex14_N PF04695.8 EGO59917.1 - 6.4 6.8 9.9 1.4 8.9 0.7 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EpuA PF11772.3 EGO59918.1 - 0.13 11.7 0.3 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta MIF4G PF02854.14 EGO59919.1 - 5.9e-60 202.2 0.1 1.2e-27 96.6 0.0 3.7 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 EGO59919.1 - 2.1e-57 193.6 21.9 2.1e-57 193.6 15.2 2.4 2 0 0 2 2 2 1 Up-frameshift suppressor 2 KH_1 PF00013.24 EGO59920.1 - 1.3e-25 88.7 1.6 1.5e-07 30.9 0.1 7.3 8 0 0 8 8 8 5 KH domain KH_3 PF13014.1 EGO59920.1 - 5.5e-24 83.3 3.0 9.3e-07 28.3 0.0 5.8 5 0 0 5 5 5 4 KH domain Mur_ligase_C PF02875.16 EGO59920.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain HAD_2 PF13419.1 EGO59923.1 - 1.4e-31 110.0 0.9 1.7e-31 109.7 0.6 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO59923.1 - 3.1e-06 26.7 0.0 5.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EGO59923.1 - 0.00024 21.5 0.0 0.00055 20.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EGO59923.1 - 0.0081 15.8 0.2 0.061 12.9 0.2 2.0 1 1 0 1 1 1 1 Acid Phosphatase TOM20_plant PF06552.7 EGO59923.1 - 0.095 12.2 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 DNA_ligase_IV PF11411.3 EGO59923.1 - 0.8 9.4 3.1 12 5.7 0.9 2.6 2 0 0 2 2 2 0 DNA ligase IV Med21 PF11221.3 EGO59924.1 - 1.4e-47 161.2 6.0 1.6e-47 161.1 4.1 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 EGO59924.1 - 0.019 14.7 8.8 0.099 12.3 4.2 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Apc4 PF12896.2 EGO59924.1 - 0.084 12.1 0.7 0.19 11.0 0.1 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Cauli_AT PF03233.8 EGO59924.1 - 0.1 12.3 0.5 0.24 11.0 0.3 1.7 2 0 0 2 2 2 0 Aphid transmission protein TMF_DNA_bd PF12329.3 EGO59924.1 - 0.25 11.1 12.8 0.079 12.7 6.5 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 EGO59924.1 - 0.32 9.9 5.1 0.51 9.3 3.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EGO59924.1 - 7.6 6.0 12.4 2.6 7.6 5.6 1.9 2 0 0 2 2 2 0 IncA protein DUF2034 PF10356.4 EGO59925.1 - 3.7e-30 104.4 0.0 1.4e-26 92.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EGO59925.1 - 1.7e-08 34.2 0.0 3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease DUF2094 PF09867.4 EGO59926.1 - 0.094 12.6 0.0 0.094 12.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2094) DUF605 PF04652.11 EGO59927.1 - 0.4 10.0 16.5 0.52 9.6 11.4 1.1 1 0 0 1 1 1 0 Vta1 like U1snRNP70_N PF12220.3 EGO59927.1 - 3.4 8.0 12.8 7.5 6.9 3.4 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Lon_C PF05362.8 EGO59928.1 - 2.9e-65 219.4 0.1 8.9e-65 217.8 0.0 1.9 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EGO59928.1 - 4.5e-37 127.7 0.4 1.4e-36 126.1 0.0 2.1 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EGO59928.1 - 4.8e-22 78.5 0.0 1.2e-21 77.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EGO59928.1 - 5.1e-09 35.6 0.0 1.2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EGO59928.1 - 2.5e-06 27.2 0.0 5.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGO59928.1 - 2.6e-06 27.4 0.0 7.5e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EGO59928.1 - 3e-05 24.8 0.3 0.00022 22.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGO59928.1 - 5.7e-05 23.2 0.1 0.0013 18.9 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EGO59928.1 - 9.5e-05 21.2 0.1 0.00022 20.0 0.0 1.5 2 0 0 2 2 2 1 PrkA AAA domain RuvB_N PF05496.7 EGO59928.1 - 0.00012 21.1 0.1 0.001 18.2 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGO59928.1 - 0.00028 20.9 2.9 0.008 16.1 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 EGO59928.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGO59928.1 - 0.028 14.7 0.0 0.028 14.7 0.0 2.4 3 0 0 3 3 1 0 AAA domain AAA_25 PF13481.1 EGO59928.1 - 0.036 13.4 0.4 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EGO59928.1 - 0.037 13.4 0.1 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EGO59928.1 - 0.042 14.0 0.0 0.22 11.7 0.0 2.3 2 0 0 2 2 1 0 RNA helicase MobB PF03205.9 EGO59928.1 - 0.051 13.2 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EGO59928.1 - 0.055 13.3 0.1 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGO59928.1 - 0.058 12.5 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Tad PF13400.1 EGO59929.1 - 0.28 11.2 6.7 0.45 10.5 4.7 1.2 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Pkinase PF00069.20 EGO59930.1 - 1.7e-11 43.7 0.0 1.2e-09 37.7 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGO59930.1 - 1.9e-08 33.6 0.0 1.6e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Cyt-b5 PF00173.23 EGO59931.1 - 1.4e-17 63.2 0.0 4.3e-17 61.6 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EGO59931.1 - 3.4e-17 62.7 8.6 3.4e-17 62.7 6.0 1.8 1 1 1 2 2 2 1 Fatty acid desaturase HTH_Tnp_Tc5 PF03221.11 EGO59932.1 - 1.1e-19 70.0 5.5 4e-08 32.9 0.0 5.9 5 1 0 5 5 5 4 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.6 EGO59932.1 - 1.9e-13 49.8 0.1 5.7e-13 48.3 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EGO59932.1 - 3.5e-05 23.3 0.5 8.6e-05 22.0 0.4 1.7 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 EGO59932.1 - 0.027 14.8 23.5 0.016 15.5 2.9 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO59932.1 - 0.028 14.7 19.5 0.036 14.4 2.6 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type BIR PF00653.16 EGO59932.1 - 1.4 9.3 6.3 5.5 7.4 0.0 3.2 1 1 0 2 2 2 0 Inhibitor of Apoptosis domain PAN_1 PF00024.21 EGO59933.1 - 0.0013 18.3 0.1 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 PAN domain Antimicrobial10 PF08105.6 EGO59933.1 - 2.1 8.0 4.6 4.3 7.0 2.4 2.1 2 0 0 2 2 2 0 Metchnikowin family Voldacs PF03517.8 EGO59934.1 - 0.49 10.2 13.1 0.11 12.3 0.8 2.6 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Pribosyltran_N PF13793.1 EGO59935.1 - 1.6e-42 143.9 0.0 1.2e-40 137.8 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EGO59935.1 - 2.6e-35 121.8 0.7 5.5e-28 97.9 0.2 3.1 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EGO59935.1 - 2.3e-06 27.3 0.4 0.0005 19.8 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosyl transferase domain UPRTase PF14681.1 EGO59935.1 - 0.068 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase XPG_I_2 PF12813.2 EGO59936.1 - 3.9e-69 232.8 0.0 8.3e-69 231.8 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 EGO59936.1 - 0.0087 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region HEAT_2 PF13646.1 EGO59937.1 - 7.6e-36 122.2 4.5 6.9e-16 58.3 0.1 3.4 2 2 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 EGO59937.1 - 2.9e-23 79.9 2.8 0.0045 17.3 0.0 6.4 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EGO59937.1 - 1e-10 41.7 8.3 0.0073 16.7 0.2 4.8 2 2 3 5 5 5 4 HEAT-like repeat HEAT PF02985.17 EGO59937.1 - 1.7e-09 36.9 5.9 0.023 14.7 0.0 5.8 7 0 0 7 7 7 3 HEAT repeat Arm PF00514.18 EGO59937.1 - 0.0004 20.0 0.4 3.6 7.5 0.0 3.6 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat TPR_11 PF13414.1 EGO59937.1 - 0.012 15.2 0.2 1.6 8.4 0.1 2.8 2 1 1 3 3 3 0 TPR repeat TFIIS_C PF01096.13 EGO59938.1 - 1.7e-14 53.1 0.8 1.7e-14 53.1 0.6 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EGO59938.1 - 2.2e-06 27.2 3.0 2.2e-06 27.2 2.0 2.5 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.1 EGO59938.1 - 0.0028 17.0 12.0 0.83 9.2 0.4 3.5 3 0 0 3 3 3 2 zinc-ribbon domain C1_1 PF00130.17 EGO59938.1 - 0.0074 15.9 5.1 0.015 15.0 0.7 2.2 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.2 EGO59938.1 - 0.041 13.7 9.0 0.094 12.5 1.0 2.4 2 1 0 2 2 2 0 Double zinc ribbon tRNA-synt_1f PF01921.13 EGO59938.1 - 0.069 11.8 1.2 0.1 11.2 0.1 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (K) HypA PF01155.14 EGO59938.1 - 0.08 12.6 7.4 1.7 8.3 0.6 2.4 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family IBR PF01485.16 EGO59938.1 - 0.16 11.8 8.9 0.21 11.4 0.8 2.3 2 1 0 2 2 2 0 IBR domain zf-ISL3 PF14690.1 EGO59938.1 - 0.17 11.9 9.0 0.29 11.1 0.1 3.2 2 1 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TerY-C PF15616.1 EGO59938.1 - 0.19 11.6 4.5 1.3 8.9 0.1 2.2 2 0 0 2 2 2 0 TerY-C metal binding domain Lar_restr_allev PF14354.1 EGO59938.1 - 0.27 11.5 9.1 0.85 9.9 0.1 3.1 2 1 0 2 2 2 0 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.6 EGO59938.1 - 0.32 10.6 11.4 1.1 8.9 0.9 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 EGO59938.1 - 0.5 10.3 13.6 0.5 10.3 0.5 3.0 3 1 0 3 3 3 0 Zinc ribbon domain Zn_ribbon_recom PF13408.1 EGO59938.1 - 3 8.1 14.1 3.7 7.8 0.1 3.3 2 2 2 4 4 4 0 Recombinase zinc beta ribbon domain DUF2072 PF09845.4 EGO59938.1 - 5.1 7.0 7.5 3.4 7.6 0.3 2.3 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) zf-CHY PF05495.7 EGO59938.1 - 5.6 7.2 7.5 3.9 7.6 0.6 2.3 2 1 0 2 2 2 0 CHY zinc finger Nudix_N_2 PF14803.1 EGO59938.1 - 5.8 6.6 7.9 15 5.3 0.0 3.4 3 0 0 3 3 3 0 Nudix N-terminal zf-IS66 PF13005.2 EGO59938.1 - 7.7 6.5 12.5 16 5.5 0.3 4.3 5 0 0 5 5 5 0 zinc-finger binding domain of transposase IS66 zinc_ribbon_4 PF13717.1 EGO59938.1 - 8.9 6.0 9.7 11 5.7 0.2 3.4 4 0 0 4 4 4 0 zinc-ribbon domain Nipped-B_C PF12830.2 EGO59939.1 - 2.9e-47 160.7 0.9 4.9e-46 156.7 0.5 3.0 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EGO59939.1 - 5.8e-11 42.1 1.0 5.8e-11 42.1 0.7 3.1 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EGO59939.1 - 1.8e-07 30.6 0.4 0.17 12.0 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 EGO59939.1 - 0.0045 16.8 2.6 1.2 8.9 0.0 4.4 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Methyltransf_23 PF13489.1 EGO59940.1 - 5.9e-10 39.1 0.0 1.7e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO59940.1 - 6.8e-08 32.8 0.0 2.3e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO59940.1 - 8e-06 25.5 0.0 0.00015 21.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO59940.1 - 2.6e-05 24.5 0.0 6.2e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO59940.1 - 0.00022 21.7 0.0 0.0059 17.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO59940.1 - 0.0044 17.3 0.0 0.047 14.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO59940.1 - 0.015 14.3 0.0 0.035 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_29 PF03141.11 EGO59940.1 - 0.025 12.9 0.0 0.12 10.7 0.0 1.8 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase YqeY PF09424.5 EGO59941.1 - 6.5e-25 87.6 4.9 9.5e-25 87.1 3.4 1.2 1 0 0 1 1 1 1 Yqey-like protein SNF2_N PF00176.18 EGO59942.1 - 1.9e-72 243.6 0.0 2.7e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO59942.1 - 6.8e-11 41.8 0.0 1.4e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 EGO59942.1 - 2.1e-08 34.0 0.0 4.5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain DEAD PF00270.24 EGO59942.1 - 7.5e-06 25.5 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EGO59942.1 - 0.0062 16.2 6.7 0.012 15.3 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain WW PF00397.21 EGO59942.1 - 0.062 13.1 0.4 0.14 12.0 0.3 1.6 1 0 0 1 1 1 0 WW domain zf-RING_2 PF13639.1 EGO59942.1 - 0.063 13.1 4.1 0.16 11.8 2.8 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 EGO59942.1 - 0.074 12.7 5.5 0.18 11.5 3.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Bromo_coat PF01318.13 EGO59942.1 - 0.11 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Bromovirus coat protein zf-C3HC4_2 PF13923.1 EGO59942.1 - 0.18 11.8 3.2 0.42 10.6 2.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pex2_Pex12 PF04757.9 EGO59944.1 - 5e-59 199.4 3.0 6.3e-59 199.1 2.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EGO59944.1 - 2e-05 24.3 2.4 3.3e-05 23.6 1.7 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EGO59944.1 - 4.3e-05 23.4 3.1 7.4e-05 22.7 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO59944.1 - 0.0011 18.7 2.2 0.0016 18.1 1.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGO59944.1 - 0.044 13.4 2.4 0.065 12.9 1.7 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO59944.1 - 0.12 12.0 3.3 0.21 11.2 2.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.6 EGO59944.1 - 0.16 11.6 0.2 0.36 10.5 0.1 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain 4HBT PF03061.17 EGO59945.1 - 1e-12 47.9 0.1 1.5e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF3597 PF12200.3 EGO59945.1 - 0.19 12.0 1.1 0.55 10.6 0.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3597) IER PF05760.7 EGO59945.1 - 0.55 10.1 6.3 0.73 9.7 4.4 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) TFIIA PF03153.8 EGO59945.1 - 7.9 6.2 8.1 9.9 5.9 5.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box PF00646.28 EGO59946.1 - 1.6e-05 24.4 0.0 7.1e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EGO59946.1 - 0.0004 20.0 0.0 0.00097 18.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.13 EGO59947.1 - 5.2e-62 209.0 0.1 8e-62 208.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EGO59947.1 - 1.4e-06 28.2 8.8 0.00015 21.9 0.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO59947.1 - 8e-06 25.8 10.9 0.00044 20.3 0.7 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGO59947.1 - 1.6 9.1 13.3 0.24 11.7 0.6 3.0 3 0 0 3 3 3 0 Zinc-finger double domain SAP30_Sin3_bdg PF13867.1 EGO59948.1 - 6.4e-12 45.1 0.2 2.3e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 SSP160 PF06933.6 EGO59948.1 - 0.31 8.9 12.0 0.41 8.5 8.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 EGO59948.1 - 0.45 10.2 9.1 0.78 9.5 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 EGO59948.1 - 0.58 9.9 16.5 0.93 9.2 11.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Chitin_synth_1 PF01644.12 EGO59949.1 - 7.1e-84 279.5 0.1 1e-83 279.0 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EGO59949.1 - 1.8e-32 110.8 0.1 4.1e-32 109.6 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EGO59949.1 - 2.2e-22 79.1 3.4 5.4e-19 67.9 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EGO59949.1 - 4e-10 39.7 0.5 4e-10 39.7 0.3 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGO59949.1 - 9.2e-06 25.6 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 TFIIA PF03153.8 EGO59949.1 - 0.044 13.6 9.5 0.069 13.0 6.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NIR_SIR PF01077.17 EGO59950.1 - 1.2e-56 190.4 0.3 1.3e-48 164.3 0.0 2.9 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EGO59950.1 - 1.2e-32 111.2 0.0 5.5e-16 57.9 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EGO59950.1 - 3.6e-26 91.8 0.0 1.1e-25 90.3 0.0 1.9 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EGO59950.1 - 6.8e-08 32.3 0.7 3.6e-07 29.9 0.1 2.4 2 1 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.6 EGO59951.1 - 7.5e-60 201.8 1.0 8.7e-60 201.6 0.7 1.0 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF2975 PF11188.3 EGO59951.1 - 0.035 13.8 0.2 0.035 13.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) UNC-93 PF05978.11 EGO59951.1 - 0.037 13.5 0.4 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Ribosomal_L24e PF01246.15 EGO59954.1 - 1.5e-26 92.0 3.3 3.4e-26 90.8 2.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Ras PF00071.17 EGO59955.1 - 3.5e-57 192.2 0.1 5e-57 191.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO59955.1 - 1.4e-19 70.7 0.0 2.2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO59955.1 - 2.4e-16 59.4 0.1 3.2e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGO59955.1 - 1e-07 31.6 0.0 4.8e-07 29.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGO59955.1 - 3.1e-05 23.2 0.1 4.4e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGO59955.1 - 6e-05 22.3 0.0 8.4e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGO59955.1 - 6.9e-05 22.7 0.0 0.00015 21.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EGO59955.1 - 0.00085 18.8 0.0 0.0014 18.0 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EGO59955.1 - 0.034 13.9 0.1 3.1 7.5 0.0 2.3 2 1 0 2 2 2 0 Dynamin family AAA_28 PF13521.1 EGO59955.1 - 0.043 13.7 0.1 0.61 10.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGO59955.1 - 0.057 13.3 0.1 0.11 12.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain Nop53 PF07767.6 EGO59956.1 - 7.8e-101 337.8 46.0 9.2e-101 337.6 31.9 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Glyco_hydro_35 PF01301.14 EGO59956.1 - 0.053 12.8 0.2 0.14 11.4 0.1 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Adaptin_N PF01602.15 EGO59957.1 - 4.8e-134 447.5 11.5 6e-134 447.2 7.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EGO59957.1 - 3.6e-17 62.7 0.4 3.6e-17 62.7 0.3 2.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EGO59957.1 - 7.3e-16 58.2 4.7 2e-09 37.5 0.2 4.6 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EGO59957.1 - 1.1e-10 40.6 3.2 0.075 13.1 0.0 5.2 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EGO59957.1 - 0.00013 22.2 4.7 0.81 10.2 0.2 5.8 4 1 2 6 6 6 1 HEAT-like repeat Atx10homo_assoc PF09759.4 EGO59957.1 - 0.0018 17.9 0.0 0.64 9.7 0.0 3.9 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 EGO59957.1 - 0.0047 16.2 3.1 1.7 7.9 0.0 3.4 3 1 0 3 3 3 2 CLASP N terminal Arm PF00514.18 EGO59957.1 - 0.048 13.5 3.9 1.5 8.7 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 EGO59957.1 - 0.055 13.3 1.6 2.8 7.9 0.0 3.6 3 1 2 5 5 5 0 Protein of unknown function (DUF2435) DUF1077 PF06417.7 EGO59958.1 - 4.2e-58 194.1 2.3 5e-58 193.9 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) MARVEL PF01284.18 EGO59959.1 - 2.1e-27 95.7 4.0 2.5e-27 95.4 2.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain CD20 PF04103.10 EGO59959.1 - 0.045 13.6 9.7 0.077 12.9 6.7 1.6 1 1 0 1 1 1 0 CD20-like family DUF202 PF02656.10 EGO59959.1 - 0.9 9.8 0.0 0.9 9.8 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Rad60-SLD_2 PF13881.1 EGO59961.1 - 4.1e-12 45.9 0.0 4.6e-11 42.5 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGO59961.1 - 2.5e-05 23.5 0.0 5.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EGO59961.1 - 0.0015 18.7 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UMP1 PF05348.6 EGO59962.1 - 2.2e-22 79.4 0.1 7.6e-22 77.6 0.1 1.9 1 1 1 2 2 2 1 Proteasome maturation factor UMP1 ABC_tran PF00005.22 EGO59963.1 - 6.9e-23 81.4 0.0 3.5e-10 40.3 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGO59963.1 - 4.2e-11 43.3 0.0 0.0015 18.5 0.0 4.0 4 0 0 4 4 4 2 AAA domain SbcCD_C PF13558.1 EGO59963.1 - 4.1e-07 29.8 0.1 0.00092 19.0 0.1 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EGO59963.1 - 7.7e-06 26.7 0.0 0.092 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EGO59963.1 - 9.9e-05 22.8 0.0 0.065 13.7 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 EGO59963.1 - 0.0001 22.6 0.0 0.073 13.3 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGO59963.1 - 0.0002 20.8 0.1 0.089 12.3 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_14 PF13173.1 EGO59963.1 - 0.00048 20.0 0.0 0.38 10.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EGO59963.1 - 0.00062 19.3 0.1 0.056 12.9 0.0 2.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_25 PF13481.1 EGO59963.1 - 0.0016 17.8 0.0 2.8 7.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EGO59963.1 - 0.0026 17.9 0.0 1.1 9.3 0.0 2.9 4 0 0 4 4 2 1 AAA domain AAA_10 PF12846.2 EGO59963.1 - 0.0029 17.1 0.0 0.88 8.9 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EGO59963.1 - 0.003 17.5 0.3 2.3 8.1 0.0 2.8 3 1 0 3 3 2 2 AAA ATPase domain SRPRB PF09439.5 EGO59963.1 - 0.039 13.1 0.0 2.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 EGO59963.1 - 0.043 13.6 0.0 4 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EGO59963.1 - 0.063 12.8 0.0 7.6 6.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EGO59963.1 - 0.063 13.4 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 EGO59963.1 - 0.087 13.0 0.0 0.68 10.1 0.0 2.5 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EGO59963.1 - 0.13 11.7 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EGO59963.1 - 0.17 11.5 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.1 EGO59963.1 - 0.35 9.2 0.1 0.52 8.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.9 EGO59964.1 - 7e-21 75.0 0.0 1e-20 74.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGO59964.1 - 9e-14 51.6 0.0 1.9e-10 41.0 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EGO59964.1 - 3.6e-07 29.0 0.3 7.9e-07 27.9 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EGO59964.1 - 2.6e-06 27.4 0.1 7.7e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EGO59964.1 - 8.5e-06 25.2 0.5 2.9e-05 23.5 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EGO59964.1 - 0.00075 18.7 1.1 0.0016 17.6 0.7 1.5 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.1 EGO59964.1 - 0.023 14.7 0.0 0.22 11.5 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PRK PF00485.13 EGO59965.1 - 4.1e-56 189.6 0.0 6.2e-56 189.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EGO59965.1 - 1.1e-40 139.0 0.0 1.8e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EGO59965.1 - 1.9e-10 41.6 0.1 5.4e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO59965.1 - 3.9e-07 30.4 0.0 7.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EGO59965.1 - 6e-05 22.7 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 EGO59965.1 - 8.8e-05 22.4 0.0 0.00054 19.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EGO59965.1 - 0.003 17.8 0.7 0.0067 16.7 0.1 1.8 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EGO59965.1 - 0.0042 16.5 0.4 0.015 14.8 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain NB-ARC PF00931.17 EGO59965.1 - 0.0059 15.4 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.7 EGO59965.1 - 0.009 15.1 0.0 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EGO59965.1 - 0.013 15.5 0.4 0.071 13.0 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 EGO59965.1 - 0.021 14.5 0.0 0.056 13.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EGO59965.1 - 0.022 14.6 0.0 0.066 13.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 T2SE PF00437.15 EGO59965.1 - 0.043 12.7 0.0 0.099 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 EGO59965.1 - 0.052 13.2 0.0 0.28 10.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 EGO59965.1 - 0.054 12.2 0.0 0.13 11.0 0.0 1.6 1 0 0 1 1 1 0 ArgK protein FtsK_SpoIIIE PF01580.13 EGO59965.1 - 0.065 12.7 0.2 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EGO59965.1 - 0.077 13.1 0.0 0.2 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGO59965.1 - 0.1 12.5 0.0 0.51 10.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 EGO59965.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EGO59965.1 - 0.11 11.9 0.3 0.49 9.7 0.1 2.0 2 0 0 2 2 2 0 AAA-like domain HET PF06985.6 EGO59966.1 - 4.2e-28 98.2 0.0 8.3e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 EGO59966.1 - 1.8e-18 67.0 1.4 1.8e-18 67.0 0.9 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGO59966.1 - 4.2e-09 36.3 1.6 7.5e-09 35.5 1.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGO59966.1 - 3.6e-06 26.9 0.1 6.4e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CLTH PF10607.4 EGO59967.1 - 1.4e-32 112.3 0.5 1.8e-32 112.0 0.3 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EGO59967.1 - 4.4e-11 42.1 0.1 1.4e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 LisH ETC_C1_NDUFA4 PF04800.7 EGO59968.1 - 1.5e-39 133.8 0.4 2.5e-39 133.2 0.3 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2188 PF09954.4 EGO59968.1 - 0.035 14.0 0.1 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) F1F0-ATPsyn_F PF10791.4 EGO59969.1 - 6.7e-40 135.2 0.5 7.6e-40 135.0 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EGO59969.1 - 0.021 14.8 0.1 0.029 14.4 0.1 1.3 1 1 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Aminotran_1_2 PF00155.16 EGO59971.1 - 1.1e-13 50.9 0.0 3.2e-08 32.9 0.0 2.5 2 1 0 2 2 2 2 Aminotransferase class I and II DUF384 PF04064.8 EGO59971.1 - 0.067 12.7 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF384) Sua5_yciO_yrdC PF01300.13 EGO59971.1 - 0.071 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Telomere recombination MOZ_SAS PF01853.13 EGO59972.1 - 1.2e-85 285.5 0.3 1.7e-85 285.0 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EGO59972.1 - 9.7e-18 63.6 0.0 2.9e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF2316 PF10078.4 EGO59972.1 - 0.015 15.3 0.2 0.62 10.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Acetyltransf_7 PF13508.1 EGO59972.1 - 0.038 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO59972.1 - 0.06 13.3 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DDRGK PF09756.4 EGO59972.1 - 0.11 11.8 0.0 0.11 11.8 0.0 2.9 3 1 0 4 4 4 0 DDRGK domain RNase_T PF00929.19 EGO59973.1 - 3.3e-23 82.7 0.0 4.9e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EGO59973.1 - 0.00062 19.2 0.0 0.002 17.6 0.0 1.8 2 1 0 2 2 2 1 3'-5' exonuclease FGF-BP1 PF06473.7 EGO59973.1 - 0.54 9.8 9.7 0.9 9.0 6.7 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) CMAS PF02353.15 EGO59974.1 - 5.4e-58 196.2 0.0 1.4e-42 145.7 0.0 2.6 1 1 1 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EGO59974.1 - 2.2e-08 33.9 0.0 3.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO59974.1 - 5.5e-08 33.3 0.0 1.1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO59974.1 - 1.8e-05 25.1 0.0 3.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO59974.1 - 0.0002 21.8 0.0 0.00045 20.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO59974.1 - 0.00038 20.0 0.0 0.00064 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGO59974.1 - 0.0006 19.4 0.0 0.00098 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EGO59974.1 - 0.017 15.1 0.0 0.057 13.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EGO59974.1 - 0.041 13.2 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 EGO59974.1 - 0.05 13.0 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_3 PF01596.12 EGO59974.1 - 0.052 12.5 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase TRAPPC-Trs85 PF12739.2 EGO59976.1 - 4.1e-120 401.2 1.8 6.5e-120 400.5 1.2 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Polysacc_deac_1 PF01522.16 EGO59977.1 - 1.4e-12 47.3 0.0 2.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EGO59977.1 - 0.043 13.2 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) INCENP_ARK-bind PF03941.10 EGO59978.1 - 1.9e-11 43.6 0.2 1.1e-10 41.1 0.1 2.5 1 1 0 1 1 1 1 Inner centromere protein, ARK binding region zf-C3HC4 PF00097.20 EGO59979.1 - 1.2e-07 31.2 20.8 2.4e-07 30.2 9.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 EGO59979.1 - 4.2e-07 29.3 0.4 7.9e-07 28.4 0.3 1.5 1 0 0 1 1 1 1 SAP domain zf-C3HC4_2 PF13923.1 EGO59979.1 - 1.8e-06 27.8 20.9 2.5e-06 27.3 10.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO59979.1 - 2.4e-06 27.1 13.1 2.4e-06 27.1 9.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGO59979.1 - 3.5e-06 26.5 11.3 3.5e-06 26.5 7.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO59979.1 - 8.9e-06 25.4 20.7 2.3e-05 24.1 10.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 EGO59979.1 - 2.1e-05 24.1 4.1 2.1e-05 24.1 2.9 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein U-box PF04564.10 EGO59979.1 - 0.00061 19.7 0.0 0.0028 17.5 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-C3HC4_4 PF15227.1 EGO59979.1 - 0.0015 18.3 18.5 0.002 17.9 9.6 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGO59979.1 - 0.0072 16.4 11.3 0.019 15.0 5.9 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EGO59979.1 - 0.013 15.2 9.5 0.013 15.2 6.6 2.8 2 0 0 2 2 2 0 RING-type zinc-finger zf-Apc11 PF12861.2 EGO59979.1 - 0.93 9.3 5.9 2.5 7.9 4.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MFS_1 PF07690.11 EGO59980.1 - 8.7e-33 113.4 25.0 8.7e-33 113.4 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGO59980.1 - 0.1 12.3 4.0 0.74 9.6 0.0 3.7 3 1 0 3 3 3 0 MFS_1 like family Imm_superinfect PF14373.1 EGO59980.1 - 0.41 10.3 5.6 8.1 6.1 0.8 3.3 3 0 0 3 3 3 0 Superinfection immunity protein Fungal_trans PF04082.13 EGO59981.1 - 0.00054 18.9 0.0 0.00072 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain G-alpha PF00503.15 EGO59982.1 - 1.3e-126 422.4 0.4 1.6e-126 422.1 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGO59982.1 - 3.3e-16 59.0 0.2 4.5e-10 39.0 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO59982.1 - 7.8e-05 21.9 0.5 0.068 12.2 0.1 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EGO59982.1 - 0.0014 19.1 0.2 1 9.8 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 EGO59982.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cullin PF00888.17 EGO59983.1 - 5.7e-204 678.9 5.3 8.4e-204 678.4 3.7 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EGO59983.1 - 1.3e-26 92.1 8.0 1.8e-26 91.7 4.0 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain Rrf2 PF02082.15 EGO59983.1 - 0.012 15.6 0.0 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator Abi_C PF14355.1 EGO59983.1 - 0.081 12.8 0.0 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 Abortive infection C-terminus FliL PF03748.9 EGO59983.1 - 0.38 10.7 8.1 2.7 8.0 0.1 4.0 4 0 0 4 4 4 0 Flagellar basal body-associated protein FliL Mit_KHE1 PF10173.4 EGO59986.1 - 1.2e-71 240.4 0.2 1.7e-71 239.9 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Ion_trans_2 PF07885.11 EGO59987.1 - 4.8e-05 22.9 2.4 0.00015 21.4 0.0 2.3 2 0 0 2 2 2 1 Ion channel PDZ_1 PF12812.2 EGO59988.1 - 1.1e-52 175.8 0.0 5.8e-36 122.2 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 EGO59988.1 - 8.8e-16 57.5 0.1 1.8e-06 27.7 0.0 4.4 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 EGO59988.1 - 1.9e-15 56.8 0.1 2.2e-13 50.2 0.0 2.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 EGO59988.1 - 2.1e-08 34.2 0.0 0.0021 18.2 0.0 4.1 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 EGO59988.1 - 0.00024 20.7 0.0 0.0011 18.6 0.0 2.1 2 1 0 2 2 2 1 Trypsin Tricorn_PDZ PF14685.1 EGO59988.1 - 0.0071 16.1 0.1 0.19 11.5 0.0 3.1 4 0 0 4 4 4 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 EGO59988.1 - 0.046 13.1 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 EGO59988.1 - 0.11 10.9 0.1 0.21 9.9 0.1 1.4 1 0 0 1 1 1 0 Peptidase S46 DUF31 PF01732.11 EGO59988.1 - 0.54 9.5 0.2 0.9 8.7 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) DnaJ PF00226.26 EGO59989.1 - 4.1e-18 64.8 2.1 7.3e-18 64.0 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1510 PF07423.6 EGO59989.1 - 0.002 17.5 1.0 0.002 17.5 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) AA_permease PF00324.16 EGO59990.1 - 4.9e-107 358.2 38.3 5.6e-107 358.0 26.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO59990.1 - 2.2e-16 59.4 42.1 3e-16 59.0 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease TMEM173 PF15009.1 EGO59990.1 - 0.014 14.1 0.8 0.93 8.2 0.6 2.2 2 0 0 2 2 2 0 Transmembrane protein 173 PgaD PF13994.1 EGO59990.1 - 0.46 9.9 0.0 0.46 9.9 0.0 2.7 3 0 0 3 3 3 0 PgaD-like protein DUF1772 PF08592.6 EGO59990.1 - 2.2 8.0 17.9 0.095 12.4 2.0 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) CAP_N PF01213.14 EGO59991.1 - 0.44 9.7 8.9 0.17 11.1 0.1 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal CTDII PF01556.13 EGO59992.1 - 1.5e-30 104.8 1.7 8.4e-23 80.0 0.1 3.4 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 EGO59992.1 - 1.4e-26 92.0 1.4 2.2e-26 91.3 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EGO59992.1 - 1.1e-10 41.4 21.9 2.3e-10 40.3 15.2 1.6 1 0 0 1 1 1 1 DnaJ central domain Snf7 PF03357.16 EGO59993.1 - 7e-18 64.6 23.3 1.4e-17 63.6 16.1 1.6 1 0 0 1 1 1 1 Snf7 Phi_1 PF04674.7 EGO59993.1 - 0.11 11.6 1.7 0.17 11.0 0.6 1.6 2 0 0 2 2 2 0 Phosphate-induced protein 1 conserved region DUF1266 PF06889.6 EGO59993.1 - 0.43 10.3 11.2 0.47 10.2 3.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) DUF1777 PF08648.7 EGO59993.1 - 1 9.0 15.2 1.8 8.2 6.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) GAGA_bind PF06217.7 EGO59993.1 - 3.8 7.3 7.6 5.5 6.8 5.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family PVL_ORF50 PF07768.6 EGO59993.1 - 7.5 6.5 13.7 1.9 8.5 6.9 1.9 2 0 0 2 2 2 0 PVL ORF-50-like family DUF3381 PF11861.3 EGO59993.1 - 8.7 5.8 18.4 24 4.3 12.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) MCM PF00493.18 EGO59994.1 - 3.9e-138 459.7 0.9 6.7e-138 459.0 0.7 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGO59994.1 - 6.2e-17 62.2 0.1 3.6e-16 59.7 0.0 2.3 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGO59994.1 - 1.5e-07 30.8 0.0 8.4e-07 28.3 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EGO59994.1 - 0.00044 19.7 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EGO59994.1 - 0.0013 18.3 0.1 0.0043 16.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGO59994.1 - 0.02 14.6 0.1 0.1 12.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Peptidase_C14 PF00656.17 EGO59995.1 - 0.015 14.9 0.1 0.035 13.8 0.0 1.6 2 0 0 2 2 2 0 Caspase domain Methyltransf_2 PF00891.13 EGO59996.1 - 6.3e-37 127.0 0.0 1e-34 119.8 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase Mito_fiss_reg PF05308.6 EGO59997.1 - 0.025 13.9 4.4 0.041 13.2 3.0 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator EB PF01683.13 EGO59998.1 - 0.00019 21.4 24.3 0.096 12.7 3.4 3.3 3 0 0 3 3 3 3 EB module FAD_binding_3 PF01494.14 EGO60000.1 - 4.7e-92 308.7 0.0 1.2e-91 307.4 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EGO60000.1 - 2.2e-62 209.6 0.0 4e-62 208.7 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.19 EGO60000.1 - 2.8e-05 23.1 0.4 5.7e-05 22.1 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGO60000.1 - 0.00014 20.4 0.3 0.00021 19.8 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Collagen PF01391.13 EGO60000.1 - 0.00029 20.3 8.1 0.00052 19.5 5.6 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Thi4 PF01946.12 EGO60000.1 - 0.00033 19.8 0.0 0.00095 18.3 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EGO60000.1 - 0.0017 18.2 0.3 0.0067 16.3 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO60000.1 - 0.0038 16.3 0.2 0.0064 15.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGO60000.1 - 0.0071 16.3 0.2 0.052 13.5 0.0 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGO60000.1 - 0.017 14.0 0.1 0.031 13.1 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EGO60000.1 - 0.02 13.5 0.0 0.039 12.5 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 EGO60000.1 - 0.023 13.5 0.7 0.04 12.7 0.3 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A DAO PF01266.19 EGO60000.1 - 0.038 12.9 0.0 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EGO60000.1 - 0.063 12.8 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Papilloma_E5A PF05776.7 EGO60001.1 - 0.9 9.7 6.4 0.12 12.5 1.1 2.0 2 0 0 2 2 2 0 Papillomavirus E5A protein zf-RING_5 PF14634.1 EGO60002.1 - 4e-05 23.2 2.4 4e-05 23.2 1.7 3.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGO60002.1 - 0.00054 19.7 2.8 0.00054 19.7 2.0 3.1 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGO60002.1 - 0.00085 18.9 1.0 0.00085 18.9 0.7 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO60002.1 - 0.00088 19.2 2.4 0.00088 19.2 1.6 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO60002.1 - 0.0015 18.1 1.6 0.0015 18.1 1.1 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGO60002.1 - 0.07 13.0 0.3 0.07 13.0 0.2 3.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING p450 PF00067.17 EGO60003.1 - 6.5e-75 252.4 0.0 8.3e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EGO60003.1 - 8.7e-38 129.9 0.0 1.4e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EGO60003.1 - 6.5e-26 91.0 0.0 1.5e-25 89.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EGO60003.1 - 1.7e-13 51.0 0.0 4.7e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 EGO60003.1 - 0.0052 16.6 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 NrdI Flavodoxin like Flavodoxin_5 PF12724.2 EGO60003.1 - 0.032 14.2 0.0 0.094 12.7 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain Glyco_hydro_cc PF11790.3 EGO60004.1 - 1.1e-67 227.9 0.1 1.7e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Transferase PF02458.10 EGO60004.1 - 2e-14 52.8 0.0 2.1e-06 26.4 0.0 4.0 4 0 0 4 4 4 2 Transferase family FAD_oxidored PF12831.2 EGO60004.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Kinesin PF00225.18 EGO60006.1 - 2.9e-52 177.4 0.0 4.1e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain HALZ PF02183.13 EGO60006.1 - 0.0042 16.7 2.0 0.01 15.4 1.4 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper Jnk-SapK_ap_N PF09744.4 EGO60006.1 - 0.013 15.4 4.6 0.013 15.4 3.2 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Orbi_VP5 PF00901.12 EGO60006.1 - 0.3 9.2 1.3 0.5 8.5 0.9 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 AATF-Che1 PF13339.1 EGO60006.1 - 0.35 11.0 4.9 1.3 9.1 0.1 2.6 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Herpes_BLRF2 PF05812.7 EGO60006.1 - 0.4 10.5 7.1 0.24 11.2 0.4 2.4 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DUF87 PF01935.12 EGO60006.1 - 1.3 8.7 5.4 8.4 6.1 0.4 3.3 3 1 0 4 4 4 0 Domain of unknown function DUF87 IncA PF04156.9 EGO60006.1 - 2.5 7.6 9.2 3.3 7.2 2.2 2.2 2 0 0 2 2 2 0 IncA protein DUF972 PF06156.8 EGO60006.1 - 3.3 8.1 7.2 0.43 10.9 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) SH3_9 PF14604.1 EGO60007.1 - 3e-07 29.9 0.0 7e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO60007.1 - 2e-05 23.8 0.0 3.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGO60007.1 - 0.0033 16.8 0.0 0.0072 15.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Tropomyosin PF00261.15 EGO60008.1 - 0.00019 20.6 19.9 0.012 14.7 5.2 3.0 1 1 2 3 3 3 2 Tropomyosin Tropomyosin_1 PF12718.2 EGO60008.1 - 0.0011 18.7 17.9 0.0015 18.4 12.4 1.1 1 0 0 1 1 1 1 Tropomyosin like Reo_sigmaC PF04582.7 EGO60008.1 - 0.027 13.6 4.1 0.033 13.3 2.8 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ATG16 PF08614.6 EGO60008.1 - 0.027 14.2 16.8 0.13 12.1 11.4 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) LXG PF04740.7 EGO60008.1 - 0.038 13.7 4.9 0.051 13.3 3.0 1.5 1 1 0 1 1 1 0 LXG domain of WXG superfamily Fib_alpha PF08702.5 EGO60008.1 - 0.1 12.7 8.0 1.5 8.9 1.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IFT57 PF10498.4 EGO60008.1 - 0.15 10.7 8.7 0.17 10.5 6.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TMF_DNA_bd PF12329.3 EGO60008.1 - 0.22 11.3 14.8 5.7 6.8 0.6 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3005 PF11448.3 EGO60008.1 - 0.24 11.0 1.6 3.9 7.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3005) GAS PF13851.1 EGO60008.1 - 0.25 10.5 14.1 0.7 9.0 9.8 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMPIT PF07851.8 EGO60008.1 - 0.33 9.9 6.1 0.41 9.6 4.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein APG6 PF04111.7 EGO60008.1 - 0.51 9.3 15.1 0.68 8.9 10.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 BBP1_C PF15272.1 EGO60008.1 - 0.51 9.8 8.2 1.4 8.3 5.6 1.8 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal TMCO5 PF14992.1 EGO60008.1 - 0.62 9.1 10.3 0.32 10.1 3.1 1.8 1 1 1 2 2 2 0 TMCO5 family Cluap1 PF10234.4 EGO60008.1 - 0.78 8.8 13.6 1.1 8.4 9.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 KIAA1430 PF13879.1 EGO60008.1 - 0.82 10.1 6.1 9.1 6.7 2.0 2.3 1 1 1 2 2 2 0 KIAA1430 homologue ADIP PF11559.3 EGO60008.1 - 0.93 9.3 21.0 2.3 8.0 7.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spectrin PF00435.16 EGO60008.1 - 1.1 9.6 16.2 26 5.1 11.2 2.3 1 1 0 1 1 1 0 Spectrin repeat Uds1 PF15456.1 EGO60008.1 - 1.2 9.1 14.1 0.5 10.3 6.7 2.0 1 1 1 2 2 2 0 Up-regulated During Septation Vps51 PF08700.6 EGO60008.1 - 1.2 8.9 5.9 1.3 8.8 2.5 2.3 1 1 1 2 2 2 0 Vps51/Vps67 CENP-H PF05837.7 EGO60008.1 - 1.3 9.2 13.8 2.8 8.1 4.2 2.8 1 1 2 3 3 3 0 Centromere protein H (CENP-H) DUF2937 PF11157.3 EGO60008.1 - 1.4 8.2 15.1 3.4 6.9 8.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) PspB PF06667.7 EGO60008.1 - 1.7 8.6 8.7 0.21 11.5 0.8 2.8 1 1 3 4 4 4 0 Phage shock protein B DUF2959 PF11172.3 EGO60008.1 - 2 8.1 9.8 2.7 7.6 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) PIN_2 PF10130.4 EGO60008.1 - 2 8.4 7.8 3.7 7.5 2.3 2.4 1 1 1 2 2 2 0 PIN domain DUF724 PF05266.9 EGO60008.1 - 2.3 7.8 12.3 5.2 6.6 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Nup54 PF13874.1 EGO60008.1 - 2.3 7.9 16.7 6.2 6.4 11.6 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 TBPIP PF07106.8 EGO60008.1 - 2.8 7.4 9.5 15 5.1 6.4 2.0 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3435 PF11917.3 EGO60008.1 - 2.9 6.4 11.3 3.5 6.2 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Striatin PF08232.7 EGO60008.1 - 3 8.1 12.1 2.2 8.6 1.1 2.1 1 1 1 2 2 2 0 Striatin family COG2 PF06148.6 EGO60008.1 - 3 7.7 8.3 1.4 8.7 0.6 2.6 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 SlyX PF04102.7 EGO60008.1 - 3.1 8.2 19.2 0.49 10.8 3.7 2.9 1 1 1 2 2 2 0 SlyX DUF972 PF06156.8 EGO60008.1 - 3.1 8.1 10.9 4.8e+02 1.1 7.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF972) ACCA PF03255.9 EGO60008.1 - 3.3 7.2 7.2 1.5 8.3 1.6 2.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Syntaxin PF00804.20 EGO60008.1 - 3.8 7.7 12.7 5.4 7.2 4.5 2.4 1 1 1 2 2 2 0 Syntaxin IncA PF04156.9 EGO60008.1 - 4.2 6.9 19.2 9.3 5.7 13.3 1.5 1 1 0 1 1 1 0 IncA protein DUF3847 PF12958.2 EGO60008.1 - 4.8 7.0 10.2 1.2 8.8 3.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) TPR_MLP1_2 PF07926.7 EGO60008.1 - 5.9 6.6 20.2 22 4.8 0.1 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CR6_interact PF10147.4 EGO60008.1 - 6.2 6.0 16.5 0.93 8.7 5.6 2.0 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Spc7 PF08317.6 EGO60008.1 - 6.4 5.3 11.3 11 4.6 7.8 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.3 EGO60008.1 - 8 3.6 23.2 9.3 3.4 16.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3347 PF11827.3 EGO60008.1 - 8.2 6.3 9.8 15 5.5 6.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) Mto2_bdg PF12808.2 EGO60008.1 - 8.2 6.6 13.6 4.4 7.4 0.5 3.4 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4472 PF14739.1 EGO60008.1 - 8.6 6.8 14.1 7.5 7.0 4.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) CDC37_N PF03234.9 EGO60008.1 - 9.6 6.4 9.3 61 3.8 6.4 2.0 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF3584 PF12128.3 EGO60010.1 - 0.00061 17.2 5.0 0.00072 17.0 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) WEMBL PF05701.6 EGO60010.1 - 0.0012 17.4 10.9 0.0017 16.8 7.5 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light EzrA PF06160.7 EGO60010.1 - 0.0017 16.6 6.9 0.071 11.2 2.9 2.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA NPV_P10 PF05531.7 EGO60010.1 - 0.0017 18.5 11.0 0.02 15.1 5.0 3.5 1 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein GAS PF13851.1 EGO60010.1 - 0.0017 17.5 7.9 0.0017 17.5 5.5 1.7 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Spectrin PF00435.16 EGO60010.1 - 0.0049 17.1 8.3 0.69 10.2 0.1 2.5 1 1 1 2 2 2 1 Spectrin repeat Striatin PF08232.7 EGO60010.1 - 0.0099 16.1 6.7 0.02 15.2 4.6 1.8 1 1 0 1 1 1 1 Striatin family DUF2317 PF10079.4 EGO60010.1 - 0.018 13.6 5.1 0.012 14.2 2.1 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) Packaging_FI PF14000.1 EGO60010.1 - 0.021 15.0 1.7 0.032 14.4 1.1 1.5 1 0 0 1 1 1 0 DNA packaging protein FI TMF_DNA_bd PF12329.3 EGO60010.1 - 0.023 14.4 15.6 0.38 10.5 3.8 3.3 2 1 0 3 3 2 0 TATA element modulatory factor 1 DNA binding Myosin_tail_1 PF01576.14 EGO60010.1 - 0.024 12.3 8.7 0.03 12.0 5.8 1.3 1 1 0 1 1 1 0 Myosin tail 5_nucleotid PF05761.9 EGO60010.1 - 0.025 13.1 2.0 0.033 12.7 1.4 1.1 1 0 0 1 1 1 0 5' nucleotidase family Reo_sigmaC PF04582.7 EGO60010.1 - 0.03 13.5 4.0 0.029 13.5 1.9 1.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Pox_A_type_inc PF04508.7 EGO60010.1 - 0.044 13.5 6.4 0.65 9.9 0.4 4.4 4 1 1 5 5 4 0 Viral A-type inclusion protein repeat V_ATPase_I PF01496.14 EGO60010.1 - 0.047 11.5 2.0 0.047 11.5 1.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 EGO60010.1 - 0.049 13.1 10.8 0.065 12.7 5.8 2.0 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) WD40_alt PF14077.1 EGO60010.1 - 0.057 13.0 3.7 0.088 12.4 0.6 2.7 1 1 1 2 2 2 0 Alternative WD40 repeat motif TMF_TATA_bd PF12325.3 EGO60010.1 - 0.073 12.8 9.8 6.6 6.4 6.3 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Tropomyosin_1 PF12718.2 EGO60010.1 - 0.082 12.7 13.8 0.06 13.1 8.0 1.8 1 1 0 1 1 1 0 Tropomyosin like Acyl-CoA_dh_2 PF08028.6 EGO60010.1 - 0.084 13.1 4.0 1.2 9.3 1.0 2.1 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain IncA PF04156.9 EGO60010.1 - 0.093 12.3 14.0 0.42 10.1 9.7 2.0 1 1 0 1 1 1 0 IncA protein FemAB PF02388.11 EGO60010.1 - 0.1 11.2 7.9 0.55 8.8 4.5 1.9 1 1 1 2 2 2 0 FemAB family Spc7 PF08317.6 EGO60010.1 - 0.1 11.2 10.6 0.17 10.4 7.3 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Prefoldin PF02996.12 EGO60010.1 - 0.12 11.9 10.6 0.052 13.1 2.9 2.7 1 1 1 2 2 2 0 Prefoldin subunit Pox_G5 PF04599.7 EGO60010.1 - 0.15 10.7 1.1 0.2 10.2 0.8 1.3 1 0 0 1 1 1 0 Poxvirus G5 protein DUF4461 PF14688.1 EGO60010.1 - 0.16 11.3 3.5 0.23 10.7 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) AAA_13 PF13166.1 EGO60010.1 - 0.17 10.3 7.5 1.2 7.4 3.6 1.9 1 1 1 2 2 2 0 AAA domain CALCOCO1 PF07888.6 EGO60010.1 - 0.18 10.0 10.0 0.36 9.0 7.0 1.5 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Bacillus_HBL PF05791.6 EGO60010.1 - 0.2 10.9 7.0 3.7 6.8 1.2 2.5 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF972 PF06156.8 EGO60010.1 - 0.21 11.9 9.2 3.1 8.1 5.7 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Tropomyosin PF00261.15 EGO60010.1 - 0.22 10.5 10.4 0.47 9.5 6.3 1.9 1 1 0 1 1 1 0 Tropomyosin DUF4201 PF13870.1 EGO60010.1 - 0.22 10.9 7.4 0.84 9.0 4.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF2203 PF09969.4 EGO60010.1 - 0.22 11.7 3.0 0.59 10.3 2.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Occludin_ELL PF07303.8 EGO60010.1 - 0.25 12.0 2.8 0.53 11.0 1.6 1.9 1 1 0 2 2 1 0 Occludin homology domain OmpH PF03938.9 EGO60010.1 - 0.26 11.2 12.9 0.49 10.3 8.9 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.10 EGO60010.1 - 0.27 10.7 13.9 0.06 12.8 1.4 2.8 2 1 1 3 3 2 0 Septum formation initiator Shugoshin_N PF07558.6 EGO60010.1 - 0.29 10.8 4.7 1.7 8.4 1.2 2.4 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region Fez1 PF06818.10 EGO60010.1 - 0.3 11.0 10.4 0.5 10.3 7.2 1.3 1 1 0 1 1 1 0 Fez1 BLOC1_2 PF10046.4 EGO60010.1 - 0.31 11.2 8.3 0.69 10.0 3.9 2.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.7 EGO60010.1 - 0.33 11.3 15.3 0.24 11.8 5.1 3.4 1 1 1 3 3 3 0 SlyX PEP-utilisers_N PF05524.8 EGO60010.1 - 0.34 10.6 6.0 0.16 11.7 1.4 2.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Sec34 PF04136.10 EGO60010.1 - 0.34 10.5 3.4 0.66 9.6 1.9 1.6 1 1 1 2 2 2 0 Sec34-like family CENP-Q PF13094.1 EGO60010.1 - 0.39 10.7 14.3 0.77 9.7 9.6 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ADIP PF11559.3 EGO60010.1 - 0.4 10.5 14.5 0.2 11.5 6.0 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3251 PF11622.3 EGO60010.1 - 0.45 9.9 4.8 0.33 10.3 1.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3251) DUF4200 PF13863.1 EGO60010.1 - 0.58 10.1 9.0 12 5.8 3.7 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.4 EGO60010.1 - 0.59 9.9 14.1 2.1 8.1 8.6 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.7 EGO60010.1 - 0.63 9.7 7.9 0.61 9.8 1.6 2.7 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Baculo_PEP_C PF04513.7 EGO60010.1 - 0.67 9.7 8.5 6.8 6.5 5.9 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lebercilin PF15619.1 EGO60010.1 - 0.71 9.2 12.4 2.7 7.3 8.0 1.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Matrilin_ccoil PF10393.4 EGO60010.1 - 0.8 9.1 7.1 4.9 6.5 1.1 2.7 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Snapin_Pallidin PF14712.1 EGO60010.1 - 0.9 9.8 11.4 0.46 10.8 6.0 1.9 2 1 0 2 2 1 0 Snapin/Pallidin Jnk-SapK_ap_N PF09744.4 EGO60010.1 - 0.93 9.4 7.6 0.95 9.4 4.3 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Uds1 PF15456.1 EGO60010.1 - 1 9.3 9.3 4.1 7.4 6.5 2.0 1 1 0 1 1 1 0 Up-regulated During Septation XhlA PF10779.4 EGO60010.1 - 1.1 9.1 5.2 1.3 9.0 1.7 2.2 1 1 1 2 2 2 0 Haemolysin XhlA Atg14 PF10186.4 EGO60010.1 - 1.2 7.9 10.4 7.2 5.4 7.2 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fmp27_WPPW PF10359.4 EGO60010.1 - 1.3 7.4 7.0 1.4 7.2 4.3 1.5 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF812 PF05667.6 EGO60010.1 - 1.4 7.3 11.0 1.5 7.2 7.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Fib_alpha PF08702.5 EGO60010.1 - 1.7 8.7 7.7 2.4 8.2 4.5 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 EGO60010.1 - 1.8 7.5 11.8 1.5 7.8 7.3 1.5 1 1 1 2 2 2 0 Autophagy protein Apg6 CASP_C PF08172.7 EGO60010.1 - 1.9 7.4 7.7 2.9 6.8 5.3 1.5 1 1 0 1 1 1 0 CASP C terminal bZIP_1 PF00170.16 EGO60010.1 - 2 8.4 8.9 23 5.0 3.6 3.2 2 1 1 3 3 3 0 bZIP transcription factor Seryl_tRNA_N PF02403.17 EGO60010.1 - 2.1 8.3 11.4 14 5.7 2.3 2.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.6 EGO60010.1 - 2.9 7.3 11.9 6.5 6.1 5.9 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Viral_P18 PF04521.8 EGO60010.1 - 3.4 7.1 5.6 17 4.8 4.2 2.0 2 1 0 2 2 1 0 ssRNA positive strand viral 18kD cysteine rich protein DUF4559 PF15112.1 EGO60010.1 - 4.8 6.2 6.6 8.2 5.4 4.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) FliJ PF02050.11 EGO60010.1 - 5.1 7.1 13.8 9.6 6.2 7.0 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein DUF3847 PF12958.2 EGO60010.1 - 6.1 6.6 10.0 4.5 7.0 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) MerR-DNA-bind PF09278.6 EGO60010.1 - 6.2 7.3 8.6 4.4 7.7 1.6 2.6 1 1 1 2 2 2 0 MerR, DNA binding Mnd1 PF03962.10 EGO60010.1 - 7.5 6.1 11.0 6.2 6.4 6.3 1.7 1 1 1 2 2 2 0 Mnd1 family DUF4140 PF13600.1 EGO60010.1 - 8.5 6.8 10.8 1.7 9.1 2.5 2.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.6 EGO60010.1 - 9.4 5.9 11.7 10 5.8 6.7 2.1 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 Hemerythrin PF01814.18 EGO60011.1 - 0.013 15.6 1.8 0.013 15.6 1.3 2.1 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Pox_A_type_inc PF04508.7 EGO60011.1 - 0.15 11.9 2.3 29 4.7 0.0 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF445 PF04286.7 EGO60011.1 - 0.22 10.9 9.6 0.31 10.5 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) UPF0242 PF06785.6 EGO60011.1 - 0.3 9.7 17.9 0.41 9.2 12.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) ATG16 PF08614.6 EGO60011.1 - 0.31 10.8 26.1 2.2 8.0 17.5 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FHIPEP PF00771.15 EGO60011.1 - 0.46 8.7 6.7 0.59 8.3 4.7 1.1 1 0 0 1 1 1 0 FHIPEP family zf-ZPR1 PF03367.8 EGO60011.1 - 0.82 8.8 5.5 7.9 5.6 2.7 2.4 2 1 0 2 2 2 0 ZPR1 zinc-finger domain V_ATPase_I PF01496.14 EGO60011.1 - 1.7 6.4 8.5 2 6.1 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rgp1 PF08737.5 EGO60011.1 - 3 6.8 7.5 4.1 6.3 5.2 1.2 1 0 0 1 1 1 0 Rgp1 Fib_alpha PF08702.5 EGO60011.1 - 4.1 7.5 13.8 7.5 6.6 9.4 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family RFXA_RFXANK_bdg PF15289.1 EGO60011.1 - 4.2 7.5 11.0 10 6.3 7.6 1.8 1 1 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain Borrelia_P83 PF05262.6 EGO60011.1 - 6.3 4.9 20.6 9.7 4.3 14.3 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein PolyA_pol PF01743.15 EGO60011.1 - 8.5 6.6 7.3 2.9 8.1 2.3 2.0 1 1 1 2 2 2 0 Poly A polymerase head domain DUF2203 PF09969.4 EGO60011.1 - 9.5 6.4 15.6 3.8 7.7 3.6 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) AAA_19 PF13245.1 EGO60012.1 - 0.0089 15.7 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain NPV_P10 PF05531.7 EGO60013.1 - 0.00073 19.7 6.0 0.0079 16.4 0.4 6.8 3 2 2 5 5 5 2 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EGO60013.1 - 0.0033 17.0 2.6 0.0033 17.0 1.8 4.2 2 1 2 4 4 4 2 IncA protein CDC45 PF02724.9 EGO60015.1 - 1.9 6.4 5.5 2.3 6.1 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Catalase PF00199.14 EGO60017.1 - 2.6e-169 562.9 0.0 3.1e-169 562.6 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGO60017.1 - 1.4e-11 44.0 0.0 3.5e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive AA_permease PF00324.16 EGO60019.1 - 5.7e-135 450.3 48.3 6.8e-135 450.0 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO60019.1 - 6.3e-40 137.0 52.4 7.7e-40 136.7 36.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2781 PF10914.3 EGO60020.1 - 1.5e-38 131.9 7.8 1.5e-38 131.9 5.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2781) Pyridox_oxidase PF01243.15 EGO60021.1 - 0.00015 21.7 0.0 0.0021 18.0 0.0 2.2 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase adh_short PF00106.20 EGO60022.1 - 4e-19 69.1 0.1 5.3e-19 68.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO60022.1 - 6.2e-09 35.9 0.0 7.5e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO60022.1 - 2e-08 34.1 0.2 2.7e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO60022.1 - 3.4e-07 29.9 0.0 4.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGO60022.1 - 0.0051 15.7 0.0 0.007 15.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF3407 PF11887.3 EGO60022.1 - 0.05 12.8 0.3 0.094 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) NAD_binding_10 PF13460.1 EGO60022.1 - 0.078 12.9 0.1 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 NADH(P)-binding APH PF01636.18 EGO60024.1 - 4.5e-57 193.5 0.1 6.3e-57 193.0 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family MGC-24 PF05283.6 EGO60024.1 - 1.6 8.5 12.9 15 5.2 7.0 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Abhydrolase_3 PF07859.8 EGO60025.1 - 2.9e-40 138.1 0.1 1.4e-26 93.4 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO60025.1 - 0.0014 18.3 0.2 0.003 17.3 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EGO60025.1 - 0.0018 17.0 0.0 0.0026 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EGO60025.1 - 0.049 12.8 0.1 0.88 8.7 0.1 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family AAA PF00004.24 EGO60026.1 - 7.7e-16 58.5 0.0 1.4e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO60026.1 - 0.09 12.9 0.0 0.24 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain SET PF00856.23 EGO60030.1 - 0.00065 20.0 0.0 0.00095 19.4 0.0 1.3 1 0 0 1 1 1 1 SET domain SAF PF08666.7 EGO60030.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 SAF domain MFS_2 PF13347.1 EGO60030.1 - 0.35 9.2 2.0 0.47 8.7 1.4 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein GDPD PF03009.12 EGO60031.1 - 1.8e-13 50.5 0.0 2.5e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ubiq-Cytc-red_N PF09165.5 EGO60031.1 - 0.13 12.5 1.2 0.31 11.3 0.8 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal Tricorn_C1 PF14684.1 EGO60033.1 - 0.053 13.3 0.2 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Tricorn protease C1 domain Metal_resist PF13801.1 EGO60033.1 - 1.2 9.1 5.6 9 6.3 3.2 2.2 2 0 0 2 2 2 0 Heavy-metal resistance Peptidase_M20 PF01546.23 EGO60035.1 - 1.5e-34 119.1 0.1 2.4e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGO60035.1 - 2.7e-12 46.4 0.0 4.6e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Yippee-Mis18 PF03226.9 EGO60036.1 - 6.1e-19 67.8 0.0 1e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly His_biosynth PF00977.16 EGO60038.1 - 7.2e-49 166.1 0.1 2.4e-48 164.3 0.0 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EGO60038.1 - 3e-26 92.0 0.0 4.7e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EGO60038.1 - 1.1e-09 38.1 0.0 6.8e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EGO60038.1 - 9.6e-09 35.0 0.0 2.7e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.12 EGO60038.1 - 0.0056 15.5 0.0 0.013 14.3 0.0 1.6 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.8 EGO60038.1 - 0.026 13.9 0.1 0.42 10.0 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 TFIIIC_sub6 PF10419.4 EGO60039.1 - 3.5e-14 51.9 0.0 6.3e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit DUF946 PF06101.6 EGO60040.1 - 1.2e-10 40.0 0.0 2.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) DUF1302 PF06980.6 EGO60040.1 - 0.035 12.6 0.0 0.065 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) Peptidase_S8 PF00082.17 EGO60041.1 - 1e-46 159.3 20.7 1.4e-46 158.8 14.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EGO60041.1 - 1.6e-12 47.8 0.8 3.3e-12 46.8 0.1 1.9 2 0 0 2 2 2 1 Peptidase inhibitor I9 FAD_binding_3 PF01494.14 EGO60043.1 - 9.9e-07 28.1 1.9 0.0023 17.0 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EGO60043.1 - 0.00072 19.5 0.2 0.0021 18.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO60043.1 - 0.0029 16.5 0.9 0.0051 15.7 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EGO60043.1 - 0.039 13.6 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 EGO60043.1 - 0.044 13.5 0.1 0.09 12.5 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGO60043.1 - 0.092 12.6 0.1 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGO60043.1 - 0.16 10.5 0.1 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 EGO60043.1 - 0.2 10.6 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EGO60043.1 - 0.23 11.9 0.2 0.63 10.4 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PMI_typeI PF01238.16 EGO60046.1 - 5e-133 443.6 0.1 6e-133 443.4 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 EGO60046.1 - 0.00026 20.6 0.0 0.0099 15.5 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.6 EGO60046.1 - 0.009 15.4 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain ANTAR PF03861.9 EGO60046.1 - 0.13 11.8 1.4 0.31 10.6 1.0 1.6 1 0 0 1 1 1 0 ANTAR domain SHS2_Rpb7-N PF03876.12 EGO60047.1 - 7.9e-08 32.3 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 MIP-T3 PF10243.4 EGO60047.1 - 1.9e-07 29.9 30.8 1.9e-07 29.9 21.3 2.0 2 0 0 2 2 2 2 Microtubule-binding protein MIP-T3 Mitofilin PF09731.4 EGO60047.1 - 0.0018 17.0 21.3 0.0018 17.0 14.8 2.0 2 0 0 2 2 2 1 Mitochondrial inner membrane protein NmrA PF05368.8 EGO60049.1 - 2.7e-28 98.8 0.0 3.5e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EGO60049.1 - 0.00018 21.0 0.0 0.00081 18.8 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EGO60049.1 - 0.00033 20.3 0.0 0.00048 19.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO60049.1 - 0.0045 17.0 0.1 0.015 15.2 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EGO60049.1 - 0.035 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NACHT PF05729.7 EGO60050.1 - 1.4e-06 28.0 0.1 6.4e-06 25.9 0.1 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EGO60050.1 - 6.1e-05 23.0 0.4 0.00042 20.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGO60050.1 - 0.0029 17.7 0.0 0.011 15.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EGO60050.1 - 0.013 15.8 0.0 0.045 14.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter V-set PF07686.12 EGO60050.1 - 0.027 14.3 0.1 3.2 7.6 0.1 2.6 2 0 0 2 2 2 0 Immunoglobulin V-set domain AAA_29 PF13555.1 EGO60050.1 - 0.033 13.7 0.0 0.088 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NAD_binding_2 PF03446.10 EGO60050.1 - 0.038 13.8 0.2 0.073 12.9 0.2 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RNA_helicase PF00910.17 EGO60050.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Sugar_tr PF00083.19 EGO60051.1 - 3.4e-80 269.8 22.1 5.5e-77 259.2 15.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO60051.1 - 2.6e-27 95.4 30.8 4.6e-27 94.6 14.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Erythro-docking PF09277.6 EGO60051.1 - 0.024 14.3 0.5 0.048 13.3 0.4 1.4 1 0 0 1 1 1 0 Erythronolide synthase, docking Asp_Glu_race PF01177.17 EGO60052.1 - 6.8e-20 71.9 0.0 8.7e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Actin PF00022.14 EGO60053.1 - 1.9e-116 388.7 0.0 2.2e-116 388.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGO60053.1 - 0.033 12.7 0.0 0.36 9.3 0.0 2.4 1 1 0 1 1 1 0 MreB/Mbl protein Pkinase PF00069.20 EGO60054.1 - 8.2e-62 208.6 0.0 1.3e-61 208.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO60054.1 - 7.9e-31 107.0 0.0 2.7e-30 105.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO60054.1 - 0.0016 17.4 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGO60054.1 - 0.022 14.5 0.6 0.58 9.8 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family Arf PF00025.16 EGO60055.1 - 6.6e-72 240.3 0.2 7.7e-72 240.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGO60055.1 - 3e-13 49.4 0.0 3.4e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EGO60055.1 - 3.2e-12 46.0 0.0 3.8e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGO60055.1 - 8.3e-12 44.4 0.9 2.2e-08 33.2 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGO60055.1 - 2.6e-10 39.8 0.0 3.2e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGO60055.1 - 2.5e-07 31.1 0.0 3.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGO60055.1 - 0.00018 21.4 0.1 0.00045 20.1 0.1 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase CorC_HlyC PF03471.12 EGO60055.1 - 0.01 15.6 0.2 0.41 10.4 0.1 2.8 2 1 0 2 2 2 0 Transporter associated domain 6PF2K PF01591.13 EGO60055.1 - 0.013 14.5 0.1 0.024 13.7 0.1 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 EGO60055.1 - 0.12 12.2 0.1 0.44 10.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF1325 PF07039.6 EGO60056.1 - 4.4e-26 91.0 0.0 7.5e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain AA_permease_2 PF13520.1 EGO60057.1 - 2.2e-64 217.5 44.1 2.7e-64 217.2 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO60057.1 - 1.7e-23 82.7 40.2 2.1e-23 82.4 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease Amidinotransf PF02274.12 EGO60058.1 - 4.1e-07 29.3 0.0 0.00065 18.8 0.0 3.0 2 1 0 2 2 2 2 Amidinotransferase FliT PF05400.8 EGO60061.1 - 0.076 13.4 0.8 0.11 12.9 0.6 1.3 1 1 0 1 1 1 0 Flagellar protein FliT Pro_isomerase PF00160.16 EGO60062.1 - 2.7e-35 121.8 0.0 3.9e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EGO60062.1 - 2.2e-17 62.4 0.0 4.1e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO60062.1 - 6.9e-13 48.3 0.0 1.6e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO60062.1 - 1.7e-09 37.3 0.0 4.8e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 EGO60064.1 - 9.9e-08 31.7 7.1 1.6e-07 31.1 5.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_16 PF10294.4 EGO60065.1 - 1.9e-19 69.7 0.0 2.8e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGO60065.1 - 1.3e-06 28.9 0.0 3.2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO60065.1 - 0.00082 18.7 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EGO60065.1 - 0.001 18.6 0.1 0.0025 17.3 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 EGO60065.1 - 0.006 16.1 0.0 0.017 14.7 0.0 1.6 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_23 PF13489.1 EGO60065.1 - 0.007 16.1 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO60065.1 - 0.0072 16.3 0.1 0.013 15.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO60065.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.12 EGO60065.1 - 0.019 14.0 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_31 PF13847.1 EGO60065.1 - 0.037 13.6 0.1 0.079 12.5 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGO60065.1 - 0.065 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGO60065.1 - 0.092 13.2 0.1 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S24e PF01282.14 EGO60066.1 - 9.3e-36 121.4 0.0 1.4e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.1 EGO60066.1 - 0.017 14.4 0.4 0.021 14.2 0.3 1.2 1 0 0 1 1 1 0 RRXRR protein GTP_cyclohydro2 PF00925.15 EGO60072.1 - 2.1e-58 196.2 0.5 3.8e-53 179.1 0.1 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II Glyco_hydro_6 PF01341.12 EGO60074.1 - 1.1e-84 284.4 0.3 1.3e-84 284.1 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 FAD_binding_3 PF01494.14 EGO60075.1 - 1.6e-13 50.4 0.5 4.5e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Methyltransf_23 PF13489.1 EGO60076.1 - 2.1e-15 56.8 0.0 4.1e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO60076.1 - 8.9e-05 23.0 0.1 0.0016 19.0 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO60076.1 - 0.00022 21.6 0.0 0.0013 19.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO60076.1 - 0.0016 18.8 0.0 0.057 13.8 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO60076.1 - 0.003 17.1 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EGO60076.1 - 0.007 16.3 0.6 0.014 15.4 0.0 1.7 2 1 0 2 2 2 1 FtsJ-like methyltransferase PrmA PF06325.8 EGO60076.1 - 0.023 13.8 0.3 0.05 12.7 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EGO60076.1 - 0.086 12.2 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Lamp PF01299.12 EGO60077.1 - 0.91 8.6 11.2 1.2 8.1 7.7 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Epimerase PF01370.16 EGO60079.1 - 7e-14 51.8 0.0 9.6e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGO60079.1 - 7.3e-11 42.3 0.1 2.9e-10 40.4 0.1 2.0 2 1 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EGO60079.1 - 5.1e-10 39.0 0.0 2.7e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EGO60079.1 - 1.5e-05 23.8 0.0 2.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EGO60079.1 - 0.00059 19.7 0.2 0.0015 18.4 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Hexapep PF00132.19 EGO60080.1 - 2.4e-09 36.2 10.2 1.9e-05 23.9 2.1 4.4 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGO60080.1 - 0.00017 21.0 4.4 0.032 13.8 0.8 3.3 2 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase Rhodanese PF00581.15 EGO60081.1 - 1.2e-06 28.8 0.0 1.7e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain DUF1423 PF07227.6 EGO60082.1 - 6.2 5.3 5.5 6.8 5.2 3.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Sugar_tr PF00083.19 EGO60083.1 - 6e-78 262.4 20.8 6.9e-78 262.2 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO60083.1 - 2.4e-24 85.7 24.1 3.2e-20 72.1 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGO60083.1 - 3.1e-06 25.8 1.1 3.1e-06 25.8 0.7 2.8 2 2 1 3 3 3 1 MFS/sugar transport protein Peptidase_M43 PF05572.8 EGO60084.1 - 1e-18 67.4 0.3 2.5e-18 66.1 0.2 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EGO60084.1 - 1.6e-06 28.6 0.5 5.3e-06 26.9 0.3 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EGO60084.1 - 2.8e-06 27.4 6.5 2.7e-05 24.1 4.5 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EGO60084.1 - 9.6e-05 22.5 3.1 0.00017 21.6 2.2 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EGO60084.1 - 0.0038 16.7 6.5 0.024 14.1 4.5 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EGO60084.1 - 0.0047 16.6 0.0 0.0061 16.3 0.0 1.2 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EGO60084.1 - 0.015 14.1 1.0 0.023 13.6 0.5 1.3 1 1 0 1 1 1 0 Peptidase M66 Peptidase_M57 PF12388.3 EGO60084.1 - 0.041 13.2 0.8 0.041 13.2 0.6 1.7 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase CHB_HEX_C_1 PF13290.1 EGO60084.1 - 0.057 13.2 0.2 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain Kei1 PF08552.6 EGO60087.1 - 0.076 12.6 1.0 0.089 12.4 0.7 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DnaJ PF00226.26 EGO60088.1 - 8.5e-08 31.8 0.5 1.9e-07 30.7 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain MFS_1 PF07690.11 EGO60089.1 - 1.6e-25 89.5 40.6 1.4e-24 86.4 11.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily NDUF_B7 PF05676.8 EGO60090.1 - 3.8e-31 106.3 5.8 4.5e-31 106.0 4.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EGO60090.1 - 0.036 13.8 2.1 0.052 13.3 1.4 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ribosomal_60s PF00428.14 EGO60093.1 - 0.00017 21.8 0.0 0.00029 21.1 0.0 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Troponin-I_N PF11636.3 EGO60097.1 - 8.5 6.1 10.6 0.56 9.9 0.4 3.2 3 0 0 3 3 3 0 Troponin I residues 1-32 Menin PF05053.8 EGO60103.1 - 0.77 7.8 5.9 1.4 7.0 4.1 1.3 1 0 0 1 1 1 0 Menin TLP-20 PF06088.6 EGO60103.1 - 5 6.7 15.5 0.31 10.7 3.6 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) AnfO_nitrog PF09582.5 EGO60104.1 - 0.027 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Response_reg PF00072.19 EGO60106.1 - 4.7e-24 84.5 0.2 8.6e-24 83.7 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EGO60106.1 - 1.5e-23 82.6 0.0 4.1e-23 81.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGO60106.1 - 1e-18 67.0 0.1 2.4e-18 65.8 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EGO60106.1 - 2.6e-16 59.8 0.0 8.3e-14 51.8 0.0 2.8 3 0 0 3 3 3 1 PAS domain PAS PF00989.19 EGO60106.1 - 8e-09 35.2 0.0 6.2e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EGO60106.1 - 5.5e-06 26.3 0.0 0.00022 21.2 0.0 3.0 3 0 0 3 3 3 1 PAS fold Gemin7 PF11095.3 EGO60106.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) AF-4 PF05110.8 EGO60107.1 - 0.063 11.1 0.2 0.084 10.7 0.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FAD_binding_3 PF01494.14 EGO60108.1 - 2.9e-12 46.3 0.1 0.00027 20.0 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.19 EGO60108.1 - 3.5e-08 32.7 0.2 7.6e-08 31.6 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EGO60108.1 - 1.6e-07 31.2 0.0 3.4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO60108.1 - 2.8e-07 29.7 1.3 9.5e-07 28.0 0.1 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO60108.1 - 2.2e-06 27.6 0.3 1e-05 25.5 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO60108.1 - 3.4e-05 22.4 0.0 5.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EGO60108.1 - 5.9e-05 22.1 0.0 8.4e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EGO60108.1 - 0.00011 22.5 0.4 0.001 19.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO60108.1 - 0.00016 20.8 0.0 0.00029 20.0 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGO60108.1 - 0.0036 16.4 0.0 0.0059 15.7 0.0 1.2 1 0 0 1 1 1 1 Thi4 family UDPG_MGDP_dh_N PF03721.9 EGO60108.1 - 0.042 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.19 EGO60108.1 - 0.088 11.8 0.0 0.41 9.6 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EGO60108.1 - 0.099 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EGO60108.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EGO60108.1 - 0.12 12.1 0.0 0.88 9.2 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 EGO60108.1 - 0.16 12.2 0.0 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Glyco_hydro_11 PF00457.12 EGO60109.1 - 5.2e-78 260.6 21.9 6.2e-78 260.3 15.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 TSP_1 PF00090.14 EGO60114.1 - 7.6 6.7 7.2 0.39 10.8 0.4 2.2 3 0 0 3 3 3 0 Thrombospondin type 1 domain HET PF06985.6 EGO60115.1 - 3.7e-20 72.4 0.1 5.8e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HSP20 PF00011.16 EGO60117.1 - 4.8e-17 61.6 2.9 1.7e-11 43.8 1.8 2.7 2 1 0 2 2 2 2 Hsp20/alpha crystallin family PIH1 PF08190.7 EGO60117.1 - 0.12 11.8 8.3 4.2 6.7 4.3 2.1 1 1 1 2 2 2 0 pre-RNA processing PIH1/Nop17 Gag_spuma PF03276.9 EGO60117.1 - 2.7 6.2 7.3 3.1 6.0 5.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF3292 PF11696.3 EGO60118.1 - 0.016 13.1 2.0 0.021 12.7 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) NAD_binding_8 PF13450.1 EGO60119.1 - 1.5e-09 37.6 0.1 4.9e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGO60119.1 - 2.2e-05 23.5 0.2 4.7e-05 22.4 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EGO60119.1 - 3.3e-05 22.9 0.3 6.6e-05 21.9 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGO60119.1 - 0.00018 20.1 0.4 0.00035 19.1 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EGO60119.1 - 0.00019 21.3 0.0 0.00045 20.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO60119.1 - 0.00067 18.8 0.1 0.0011 18.1 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EGO60119.1 - 0.0015 17.5 0.0 0.0027 16.6 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EGO60119.1 - 0.002 17.2 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGO60119.1 - 0.0028 16.3 0.1 0.0039 15.8 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 EGO60119.1 - 0.0039 17.2 0.0 0.015 15.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EGO60119.1 - 0.0067 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GIDA PF01134.17 EGO60119.1 - 0.019 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EGO60119.1 - 0.067 12.9 0.0 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 EGO60119.1 - 0.093 12.7 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF3176 PF11374.3 EGO60120.1 - 5.9e-26 90.5 3.2 5.9e-26 90.5 2.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) GAS PF13851.1 EGO60121.1 - 0.00058 19.1 1.3 0.00071 18.8 0.9 1.0 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Virulence_RhuM PF13310.1 EGO60121.1 - 0.025 13.6 0.2 0.031 13.2 0.1 1.1 1 0 0 1 1 1 0 Virulence protein RhuM family Erp_C PF06780.6 EGO60121.1 - 0.026 14.3 0.8 0.032 14.0 0.6 1.2 1 0 0 1 1 1 0 Erp protein C-terminus Tmemb_cc2 PF10267.4 EGO60121.1 - 0.026 13.1 1.3 0.029 12.9 0.9 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Transglut_prok PF09017.5 EGO60121.1 - 0.027 13.6 0.0 0.035 13.2 0.0 1.0 1 0 0 1 1 1 0 Microbial transglutaminase Spc7 PF08317.6 EGO60121.1 - 0.028 13.0 1.3 0.03 12.9 0.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_8 PF13181.1 EGO60121.1 - 0.033 13.9 0.2 0.057 13.2 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat FlaC_arch PF05377.6 EGO60121.1 - 0.3 11.0 1.6 0.45 10.4 0.9 1.5 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Erythro-docking PF09277.6 EGO60121.1 - 0.49 10.1 2.5 1.3 8.8 0.1 2.4 2 1 1 3 3 3 0 Erythronolide synthase, docking CCDC-167 PF15188.1 EGO60121.1 - 0.7 9.8 4.7 1 9.3 3.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Aldo_ket_red PF00248.16 EGO60125.1 - 1.3e-50 171.7 0.0 1.5e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.6 EGO60126.1 - 1.4e-24 86.8 0.2 2.3e-24 86.1 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 EGO60128.1 - 1.5e-25 90.0 0.0 1.9e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGO60128.1 - 2.9e-10 40.1 0.0 9.9e-10 38.3 0.0 1.7 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGO60128.1 - 2.3e-08 34.1 0.0 3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGO60128.1 - 1.1e-05 25.4 0.1 4.1e-05 23.6 0.0 1.8 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGO60128.1 - 0.0012 18.3 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EGO60128.1 - 0.012 14.7 1.2 0.026 13.6 0.8 1.7 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Saccharop_dh PF03435.13 EGO60128.1 - 0.017 14.1 0.0 0.037 12.9 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 EGO60128.1 - 0.03 14.1 0.1 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EGO60128.1 - 0.08 13.0 0.0 0.16 12.0 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FoP_duplication PF13865.1 EGO60129.1 - 2.6 8.5 9.3 2.8 8.4 0.0 2.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 DUF3450 PF11932.3 EGO60130.1 - 0.0022 17.3 1.5 0.0031 16.8 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF4140 PF13600.1 EGO60130.1 - 0.02 15.3 2.0 0.024 15.0 1.4 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Atrophin-1 PF03154.10 EGO60130.1 - 0.052 11.6 9.8 0.063 11.4 6.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF607 PF04678.8 EGO60130.1 - 0.15 11.9 1.4 0.19 11.6 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF1840 PF08895.6 EGO60130.1 - 0.16 12.0 3.5 0.23 11.4 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Ycf1 PF05758.7 EGO60130.1 - 0.99 7.0 7.3 1.3 6.6 5.1 1.0 1 0 0 1 1 1 0 Ycf1 Sec62 PF03839.11 EGO60130.1 - 1.1 8.5 7.1 1.7 8.0 4.6 1.5 2 0 0 2 2 2 0 Translocation protein Sec62 IncA PF04156.9 EGO60130.1 - 6.4 6.3 13.1 8.7 5.8 9.1 1.1 1 0 0 1 1 1 0 IncA protein XhlA PF10779.4 EGO60130.1 - 7.1 6.6 13.7 11 5.9 9.5 1.3 1 0 0 1 1 1 0 Haemolysin XhlA DUF3682 PF12446.3 EGO60130.1 - 7.6 6.8 8.7 11 6.3 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Ank PF00023.25 EGO60132.1 - 8.1e-18 63.2 0.3 1.5e-06 27.7 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EGO60132.1 - 5e-14 52.4 0.1 3e-05 24.2 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO60132.1 - 2.5e-13 50.1 0.9 3.5e-06 27.3 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO60132.1 - 4.5e-12 45.7 0.3 3e-05 24.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EGO60132.1 - 7.4e-08 31.9 0.1 1.1e-06 28.1 0.0 2.7 2 1 0 2 2 2 1 KilA-N domain Ank_3 PF13606.1 EGO60132.1 - 7.6e-07 28.7 0.0 1.2 9.5 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat UPF0029 PF01205.14 EGO60132.1 - 0.47 10.1 2.6 0.68 9.6 0.3 2.5 2 0 0 2 2 2 0 Uncharacterized protein family UPF0029 DUF1690 PF07956.6 EGO60132.1 - 2.3 8.1 10.6 0.22 11.4 2.2 2.6 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) EamA PF00892.15 EGO60135.1 - 4.8e-09 36.3 32.1 1e-06 28.7 0.7 3.0 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EGO60135.1 - 8.8e-08 32.3 0.5 8.8e-08 32.3 0.3 3.6 3 2 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 EGO60135.1 - 4.1e-07 29.1 1.5 8.3e-07 28.1 1.0 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 EGO60135.1 - 0.00047 19.8 21.8 0.016 14.8 7.4 3.2 3 0 0 3 3 3 2 Triose-phosphate Transporter family MTS_N PF08468.6 EGO60136.1 - 0.12 12.1 0.2 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal Secretin_N_2 PF07655.8 EGO60136.1 - 8.5 6.8 12.7 18 5.8 8.8 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain COQ7 PF03232.8 EGO60140.1 - 0.0016 17.9 0.1 0.0019 17.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 DUF4629 PF15442.1 EGO60141.1 - 0.062 13.4 11.0 0.063 13.4 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) DUF4424 PF14415.1 EGO60141.1 - 0.31 10.5 4.8 0.35 10.3 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) SR-25 PF10500.4 EGO60141.1 - 0.34 10.3 13.4 0.36 10.2 9.3 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Spore_coat_CotO PF14153.1 EGO60141.1 - 0.64 9.4 12.1 0.67 9.3 8.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Caldesmon PF02029.10 EGO60141.1 - 0.65 8.3 17.6 0.71 8.2 12.2 1.0 1 0 0 1 1 1 0 Caldesmon MCLC PF05934.6 EGO60141.1 - 0.8 7.9 5.7 0.8 7.9 3.9 1.0 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Vfa1 PF08432.5 EGO60141.1 - 0.91 9.5 13.6 1 9.3 9.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Cytomega_UL84 PF06284.6 EGO60141.1 - 1.3 7.3 8.2 1.4 7.2 5.7 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein TRAP_alpha PF03896.11 EGO60141.1 - 1.3 7.9 8.0 1.3 7.9 5.6 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ureide_permease PF07168.6 EGO60141.1 - 1.6 7.2 5.8 1.6 7.3 4.0 1.0 1 0 0 1 1 1 0 Ureide permease DUF1510 PF07423.6 EGO60141.1 - 1.7 7.9 15.8 1.9 7.7 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2992 PF11208.3 EGO60141.1 - 1.8 8.4 14.9 2.2 8.2 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) RNA_polI_A34 PF08208.6 EGO60141.1 - 1.9 8.1 15.5 1.9 8.1 10.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Peptidase_S49_N PF08496.5 EGO60141.1 - 2.1 8.1 10.2 2.3 7.9 7.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Serinc PF03348.10 EGO60141.1 - 2.4 6.7 7.2 2.5 6.6 5.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) APG6 PF04111.7 EGO60141.1 - 2.8 6.9 10.9 3 6.8 7.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Pilt PF15453.1 EGO60141.1 - 2.8 7.5 8.1 3 7.4 5.6 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions NARP1 PF12569.3 EGO60141.1 - 2.8 6.5 13.3 3 6.4 9.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rtf2 PF04641.7 EGO60141.1 - 3.8 6.6 12.3 3.8 6.6 8.5 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger CDC45 PF02724.9 EGO60141.1 - 4.1 5.3 11.4 4.5 5.1 7.9 1.0 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.7 EGO60141.1 - 4.2 7.2 7.6 4.7 7.0 5.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_pol_Rpc4 PF05132.9 EGO60141.1 - 5 7.1 8.0 5.6 6.9 5.5 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4337 PF14235.1 EGO60141.1 - 5.2 6.8 10.6 5.6 6.7 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Glyco_transf_15 PF01793.11 EGO60141.1 - 5.3 5.8 8.1 5.2 5.9 5.6 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase ATP-synt_E PF05680.7 EGO60141.1 - 5.4 7.0 12.0 6.8 6.7 8.4 1.2 1 0 0 1 1 1 0 ATP synthase E chain AIF_C PF14721.1 EGO60141.1 - 6 7.1 7.8 6.4 7.0 5.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Endonuc_Holl PF10107.4 EGO60141.1 - 6.3 6.4 9.3 7 6.3 6.4 1.0 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase YqfQ PF14181.1 EGO60141.1 - 6.5 6.7 13.6 7.7 6.5 9.4 1.0 1 0 0 1 1 1 0 YqfQ-like protein RR_TM4-6 PF06459.7 EGO60141.1 - 7.8 6.3 12.5 7.9 6.2 8.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Selenoprotein_S PF06936.6 EGO60141.1 - 8.2 5.9 11.7 10 5.5 8.1 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) OAD_gamma PF04277.8 EGO60141.1 - 8.3 6.8 6.3 11 6.4 4.4 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Sec62 PF03839.11 EGO60141.1 - 9 5.6 11.1 8.7 5.6 7.7 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Macoilin PF09726.4 EGO60141.1 - 9.2 4.3 12.0 12 4.0 8.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Med19 PF10278.4 EGO60141.1 - 9.8 5.8 13.6 12 5.5 9.4 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF2514 PF10721.4 EGO60141.1 - 9.9 5.8 12.4 12 5.5 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) GidB PF02527.10 EGO60142.1 - 0.17 11.0 2.6 0.18 10.9 1.8 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G TINF2_N PF14973.1 EGO60142.1 - 0.26 11.4 4.4 0.29 11.2 2.9 1.3 1 1 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus BPL_N PF09825.4 EGO60142.1 - 0.42 9.3 3.4 0.42 9.3 2.4 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Trypan_glycop PF00913.14 EGO60142.1 - 0.94 8.3 8.3 1 8.2 5.7 1.0 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) DUF3393 PF11873.3 EGO60142.1 - 2.5 7.5 6.8 2.5 7.5 4.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) Thymidylate_kin PF02223.12 EGO60142.1 - 3.6 6.9 8.2 3.7 6.8 5.7 1.1 1 0 0 1 1 1 0 Thymidylate kinase Ribosomal_L27e PF01777.13 EGO60142.1 - 5.8 7.1 11.4 6.4 6.9 6.5 1.8 1 1 1 2 2 2 0 Ribosomal L27e protein family MotA_ExbB PF01618.11 EGO60142.1 - 7 6.2 5.7 7.4 6.1 3.9 1.1 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Adeno_terminal PF02459.10 EGO60142.1 - 7.4 4.6 7.8 7.4 4.6 5.4 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF3381 PF11861.3 EGO60143.1 - 0.67 9.4 10.9 0.73 9.3 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) RNA_polI_A34 PF08208.6 EGO60143.1 - 1.2 8.7 15.0 1.4 8.5 10.4 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3682 PF12446.3 EGO60143.1 - 1.6 9.0 9.4 2.2 8.6 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) CT47 PF15623.1 EGO60143.1 - 1.9 8.1 12.5 2.4 7.8 8.7 1.0 1 0 0 1 1 1 0 Cancer/testis gene family 47 Tim54 PF11711.3 EGO60143.1 - 2.5 6.5 10.3 2.5 6.5 7.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.3 EGO60143.1 - 3.7 6.1 9.9 4 6.0 6.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3464 PF11947.3 EGO60143.1 - 5.8 6.3 6.7 6 6.3 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) YqfQ PF14181.1 EGO60143.1 - 7.2 6.6 11.0 7.4 6.5 7.6 1.1 1 0 0 1 1 1 0 YqfQ-like protein Protocadherin PF08374.6 EGO60143.1 - 8.6 5.9 7.9 10 5.7 5.5 1.1 1 0 0 1 1 1 0 Protocadherin Sec62 PF03839.11 EGO60143.1 - 9.5 5.5 7.9 11 5.3 5.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 PcfJ PF14284.1 EGO60144.1 - 0.39 10.1 7.2 0.48 9.9 5.0 1.1 1 0 0 1 1 1 0 PcfJ-like protein DUF2956 PF11169.3 EGO60144.1 - 3.4 7.6 12.0 3.8 7.5 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) 2OG-FeII_Oxy_2 PF13532.1 EGO60145.1 - 3e-16 59.8 0.0 1.3e-15 57.7 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGO60145.1 - 2.8e-09 37.1 0.1 1.5e-07 31.5 0.0 2.8 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EGO60145.1 - 0.066 13.7 0.1 0.22 12.0 0.0 2.1 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.2 EGO60146.1 - 1.2e-27 96.0 5.5 2.8e-09 37.1 1.1 5.5 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EGO60146.1 - 8.3e-23 79.0 14.6 8.8e-06 25.2 0.0 8.7 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.1 EGO60146.1 - 9.8e-18 64.1 10.3 1.1e-06 28.9 0.1 7.1 8 1 0 8 8 8 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO60146.1 - 1.4e-16 60.1 12.5 3.4e-06 27.1 0.1 7.1 6 2 2 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO60146.1 - 1.5e-15 55.7 12.1 0.0002 21.2 0.0 8.7 10 0 0 10 10 10 3 Ankyrin repeat Ank_2 PF12796.2 EGO60147.1 - 1.8e-11 44.2 0.0 5.8e-05 23.3 0.0 4.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGO60147.1 - 1.5e-05 24.5 0.8 2.3 8.1 0.0 6.1 7 1 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.1 EGO60147.1 - 0.00011 22.6 0.3 0.066 13.7 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO60147.1 - 0.00067 19.8 5.2 0.27 11.5 0.0 4.6 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO60147.1 - 0.0043 17.1 0.2 1.1e+02 3.4 0.0 5.5 5 0 0 5 5 5 0 Ankyrin repeat SLAC1 PF03595.12 EGO60149.1 - 4.7e-61 206.2 34.3 5.6e-61 205.9 23.8 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel HET PF06985.6 EGO60150.1 - 2.2e-23 82.9 0.0 4.1e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ferritin-like PF12902.2 EGO60151.1 - 0.083 12.4 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Ferritin-like UBN2_3 PF14244.1 EGO60152.1 - 0.048 13.2 0.0 0.06 12.8 0.0 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EGO60154.1 - 0.0053 16.3 0.0 0.0061 16.1 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type FA_desaturase PF00487.19 EGO60159.1 - 6.2e-17 61.8 24.6 9.9e-17 61.2 17.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase AAA PF00004.24 EGO60160.1 - 3.2e-14 53.2 0.0 5.7e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO60160.1 - 0.00036 20.6 0.0 0.001 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO60160.1 - 0.0023 17.9 0.0 0.0077 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EGO60160.1 - 0.0023 18.7 0.4 0.097 13.4 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.9 EGO60160.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EGO60160.1 - 0.057 13.7 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EGO60160.1 - 0.079 12.4 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NAS PF03059.11 EGO60162.1 - 3.6e-67 226.4 0.0 4.4e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.1 EGO60162.1 - 0.008 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ATP-grasp_4 PF13535.1 EGO60163.1 - 4.1e-18 65.7 0.0 9.9e-16 57.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGO60163.1 - 1.6e-06 27.6 0.0 7.1e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EGO60163.1 - 0.02 13.6 0.0 4.2 6.0 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon 4HBT PF03061.17 EGO60164.1 - 1e-08 35.1 0.0 1.4e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_2 PF13279.1 EGO60165.1 - 0.001 19.5 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF3455 PF11937.3 EGO60168.1 - 3e-39 134.7 0.1 3.6e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) C2 PF00168.25 EGO60170.1 - 9.3e-11 41.4 0.0 1.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain zf-MIZ PF02891.15 EGO60171.1 - 1e-05 24.9 4.0 4.6e-05 22.8 2.8 2.1 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EGO60171.1 - 0.0044 16.4 0.1 0.012 15.1 0.1 1.8 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PLDc PF00614.17 EGO60171.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Phospholipase D Active site motif AT_hook PF02178.14 EGO60171.1 - 3.5 7.6 9.4 9.8 6.2 6.5 1.8 1 0 0 1 1 1 0 AT hook motif Abhydrolase_6 PF12697.2 EGO60172.1 - 4.5e-26 92.1 0.1 5.2e-26 91.9 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO60172.1 - 9e-16 57.9 0.7 1e-14 54.4 0.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO60172.1 - 0.008 15.7 0.1 0.015 14.9 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Amidohydro_2 PF04909.9 EGO60173.1 - 5.8e-35 121.1 3.7 6.7e-35 120.9 2.6 1.0 1 0 0 1 1 1 1 Amidohydrolase UTP15_C PF09384.5 EGO60174.1 - 7e-48 162.0 0.0 1.1e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EGO60174.1 - 1e-26 91.7 2.4 3.3e-08 33.1 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat PQQ_3 PF13570.1 EGO60174.1 - 0.07 13.4 0.7 86 3.6 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain Pkinase PF00069.20 EGO60175.1 - 5.7e-66 222.3 0.0 4.9e-65 219.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO60175.1 - 1.8e-27 96.0 0.0 8.2e-27 93.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO60175.1 - 0.023 14.4 0.1 0.075 12.7 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGO60175.1 - 0.082 11.9 0.1 0.21 10.6 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LMWPc PF01451.16 EGO60176.1 - 3.8e-38 130.9 0.0 4.3e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase P120R PF08062.6 EGO60176.1 - 0.15 12.4 0.6 9.9 6.6 0.6 2.6 2 0 0 2 2 2 0 P120R (NUC006) repeat SIS PF01380.17 EGO60177.1 - 5.5e-11 42.1 0.0 1.6e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EGO60177.1 - 0.025 14.2 0.1 0.062 13.0 0.1 1.6 1 1 0 1 1 1 0 SIS domain DUF2373 PF10180.4 EGO60178.1 - 1.1e-23 82.4 1.3 1.1e-23 82.4 0.9 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.21 EGO60179.1 - 4.4e-47 159.8 0.0 6e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGO60179.1 - 3.8e-13 48.4 0.2 3.8e-13 48.4 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF550 PF04447.7 EGO60179.1 - 0.033 13.8 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF550) IF-2B PF01008.12 EGO60179.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family UPF0546 PF10639.4 EGO60181.1 - 1.7e-36 124.4 0.5 1.1e-34 118.6 0.4 2.0 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 EGO60181.1 - 0.0012 18.8 5.0 0.0068 16.4 2.9 2.1 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EGO60181.1 - 0.0057 16.8 2.2 0.0057 16.8 1.5 1.7 2 0 0 2 2 2 1 Multidrug resistance efflux transporter DUF1211 PF06736.6 EGO60181.1 - 0.034 14.3 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) ERM PF00769.14 EGO60183.1 - 0.0062 16.0 19.5 0.0074 15.8 13.5 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family TIR_2 PF13676.1 EGO60183.1 - 0.74 9.9 5.4 1.5 8.9 3.7 1.5 1 0 0 1 1 1 0 TIR domain V_ATPase_I PF01496.14 EGO60183.1 - 1.1 6.9 10.4 1.4 6.6 7.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3464 PF11947.3 EGO60183.1 - 2.3 7.6 7.9 27 4.1 5.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) RrnaAD PF00398.15 EGO60184.1 - 5.1e-51 173.2 0.0 6.8e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EGO60184.1 - 7.2e-10 38.9 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO60184.1 - 4.3e-05 24.0 0.0 0.0001 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGO60184.1 - 8.1e-05 22.2 0.2 0.00017 21.2 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein MTS PF05175.9 EGO60184.1 - 0.0005 19.4 0.0 0.00099 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EGO60184.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EGO60184.1 - 0.0024 17.4 0.0 0.0045 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EGO60184.1 - 0.0086 15.6 0.1 0.031 13.8 0.0 1.8 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 PCMT PF01135.14 EGO60184.1 - 0.023 14.2 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EGO60184.1 - 0.031 13.9 0.0 0.078 12.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Myc_N PF01056.13 EGO60184.1 - 0.29 10.2 4.8 0.46 9.6 3.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.11 EGO60184.1 - 0.36 9.7 7.0 0.5 9.3 4.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 EGO60184.1 - 2 6.3 7.2 2.5 6.0 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EGO60184.1 - 2.8 7.1 12.8 3.8 6.6 8.9 1.1 1 0 0 1 1 1 0 SDA1 Pox_RNA_Pol_19 PF05320.7 EGO60184.1 - 5.3 6.7 8.3 8.4 6.1 5.7 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF2457 PF10446.4 EGO60184.1 - 6.2 5.4 15.6 8.7 4.9 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 EGO60184.1 - 7 5.8 9.7 12 4.9 6.7 1.4 1 0 0 1 1 1 0 NOA36 protein Arrestin_N PF00339.24 EGO60185.1 - 4.7e-15 55.6 0.0 1.4e-07 31.4 0.0 2.7 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EGO60185.1 - 0.012 14.8 0.1 0.058 12.5 0.0 1.9 2 0 0 2 2 2 0 Bul1 C terminus NOA36 PF06524.7 EGO60186.1 - 0.037 13.2 6.5 0.044 13.0 4.5 1.1 1 0 0 1 1 1 0 NOA36 protein DUF3275 PF11679.3 EGO60186.1 - 0.35 10.4 3.7 0.36 10.4 2.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) ANAPC15 PF15243.1 EGO60186.1 - 0.69 10.0 12.9 0.75 9.8 0.5 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 DUF1754 PF08555.5 EGO60186.1 - 0.72 10.4 12.8 1.5 9.4 8.8 1.6 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF2407_C PF13373.1 EGO60186.1 - 0.88 9.4 3.2 5.4 6.9 2.2 2.0 1 1 0 1 1 1 0 DUF2407 C-terminal domain CENP-B_dimeris PF09026.5 EGO60186.1 - 2.7 8.2 6.6 0.73 10.1 1.4 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4048 PF13257.1 EGO60186.1 - 3.2 7.3 10.3 5 6.6 7.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4048) Z1 PF10593.4 EGO60187.1 - 0.072 12.2 5.6 0.15 11.2 3.9 1.6 1 0 0 1 1 1 0 Z1 domain DUF1515 PF07439.6 EGO60187.1 - 6.7 6.5 15.7 2.7 7.8 5.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Ribosomal_L7Ae PF01248.21 EGO60188.1 - 1.1e-23 82.5 0.0 1.2e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.13 EGO60189.1 - 6.1e-32 110.1 0.1 7.9e-32 109.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Enkurin PF13864.1 EGO60190.1 - 4.8 7.4 8.3 1.5 9.0 2.2 2.6 2 1 0 2 2 2 0 Calmodulin-binding Ribosomal_60s PF00428.14 EGO60192.1 - 6.6e-27 93.7 14.3 8e-27 93.4 9.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.4 EGO60193.1 - 3.2e-51 172.9 6.9 2e-32 112.1 0.1 5.1 2 2 2 5 5 5 4 Protein of unknown function (DUF2408) MutS_III PF05192.13 EGO60193.1 - 0.014 15.1 0.7 0.034 13.9 0.5 1.9 1 1 0 1 1 1 0 MutS domain III MitMem_reg PF13012.1 EGO60193.1 - 0.11 12.6 1.5 0.97 9.5 0.3 2.7 1 1 0 2 2 2 0 Maintenance of mitochondrial structure and function AATF-Che1 PF13339.1 EGO60193.1 - 0.38 10.8 5.6 1.3 9.1 0.7 3.4 4 0 0 4 4 4 0 Apoptosis antagonizing transcription factor Snapin_Pallidin PF14712.1 EGO60193.1 - 0.67 10.2 10.5 0.76 10.1 0.4 4.9 5 1 2 7 7 7 0 Snapin/Pallidin DUF4366 PF14283.1 EGO60194.1 - 0.012 15.0 23.6 1.2 8.4 0.0 4.5 3 1 0 4 4 4 0 Domain of unknown function (DUF4366) CopD PF05425.8 EGO60194.1 - 1.4 9.1 3.6 4.1 7.6 0.0 3.4 4 0 0 4 4 4 0 Copper resistance protein D DUF2910 PF11139.3 EGO60194.1 - 2.6 7.1 8.3 9.4 5.2 0.9 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF2910) Motile_Sperm PF00635.21 EGO60195.1 - 2.6e-23 81.7 0.2 5.3e-23 80.7 0.0 1.6 2 0 0 2 2 2 1 MSP (Major sperm protein) domain Apolipoprotein PF01442.13 EGO60195.1 - 0.044 13.2 4.9 0.069 12.6 3.4 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Spc7 PF08317.6 EGO60195.1 - 0.052 12.2 1.5 0.07 11.7 1.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Mnd1 PF03962.10 EGO60195.1 - 0.082 12.5 1.3 0.13 11.9 0.9 1.2 1 0 0 1 1 1 0 Mnd1 family DUF1598 PF07643.6 EGO60195.1 - 0.15 12.0 2.4 2.5 8.2 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1598) DUF2077 PF09850.4 EGO60195.1 - 0.18 11.1 1.6 0.6 9.4 0.2 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF883 PF05957.8 EGO60195.1 - 0.34 11.3 10.3 5.6 7.4 7.2 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) KfrA_N PF11740.3 EGO60195.1 - 1.9 8.9 17.2 0.14 12.5 6.0 2.2 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term UBA PF00627.26 EGO60196.1 - 0.00097 18.9 0.3 0.0033 17.2 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain CAF-1_p150 PF11600.3 EGO60196.1 - 0.0048 16.2 39.9 0.0086 15.4 27.7 1.5 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal UBX PF00789.15 EGO60196.1 - 0.02 14.9 0.0 0.065 13.2 0.0 2.0 1 0 0 1 1 1 0 UBX domain zf-C2H2 PF00096.21 EGO60196.1 - 0.031 14.6 0.2 0.059 13.7 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type GATA PF00320.22 EGO60196.1 - 0.087 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 GATA zinc finger Pol_alpha_B_N PF08418.5 EGO60196.1 - 0.14 11.6 17.9 0.17 11.3 11.4 1.8 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SOBP PF15279.1 EGO60196.1 - 0.41 10.9 6.1 0.46 10.8 4.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Herpes_DNAp_acc PF04929.7 EGO60196.1 - 0.64 8.9 8.9 12 4.7 6.2 2.1 1 1 0 1 1 1 0 Herpes DNA replication accessory factor PLRV_ORF5 PF01690.12 EGO60196.1 - 1.6 7.7 13.9 2.1 7.4 9.6 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein NUDE_C PF04880.8 EGO60196.1 - 1.7 8.9 17.8 4.3 7.6 12.2 1.7 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region YCII PF03795.9 EGO60197.1 - 2e-08 34.3 0.0 2.4e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Daxx PF03344.10 EGO60198.1 - 0.024 13.1 25.8 0.034 12.6 17.9 1.3 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 EGO60198.1 - 1.4 6.5 7.1 1.5 6.4 4.9 1.1 1 0 0 1 1 1 0 Ycf1 IF-2B PF01008.12 EGO60199.1 - 2.1e-37 128.6 0.0 3.5e-37 127.9 0.0 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF1722 PF08349.6 EGO60199.1 - 0.04 13.8 0.0 0.78 9.6 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) Ribosomal_L7Ae PF01248.21 EGO60200.1 - 1e-15 56.9 0.7 1.2e-14 53.5 0.5 2.4 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Moulting_cycle PF04870.11 EGO60200.1 - 0.14 11.2 10.1 0.22 10.5 7.0 1.2 1 0 0 1 1 1 0 Moulting cycle Ycf1 PF05758.7 EGO60200.1 - 0.22 9.2 3.8 0.19 9.4 2.6 1.1 1 0 0 1 1 1 0 Ycf1 Paramyxo_ncap PF00973.14 EGO60200.1 - 1.9 7.0 6.8 2.7 6.5 4.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein TipAS PF07739.8 EGO60200.1 - 3.7 7.9 8.1 12 6.2 5.6 1.9 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain DUF1761 PF08570.5 EGO60201.1 - 7e-22 77.7 2.8 7.9e-22 77.6 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) CD20 PF04103.10 EGO60201.1 - 0.35 10.8 2.8 0.4 10.6 1.6 1.4 1 1 0 1 1 1 0 CD20-like family NIF PF03031.13 EGO60202.1 - 2e-51 173.7 0.0 2.9e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase UcrQ PF02939.11 EGO60203.1 - 3.1e-37 126.2 0.3 3.7e-37 126.0 0.2 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.20 EGO60204.1 - 2.3e-24 86.2 7.3 3e-24 85.9 4.6 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 EGO60204.1 - 0.021 14.2 1.6 0.03 13.7 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) RNase_T PF00929.19 EGO60205.1 - 5.3e-08 33.3 0.0 1.6e-05 25.2 0.0 3.0 1 1 0 1 1 1 1 Exonuclease DUF4557 PF15101.1 EGO60205.1 - 0.081 12.7 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) BTK PF00779.14 EGO60205.1 - 0.21 11.2 5.2 0.49 10.0 3.6 1.6 1 0 0 1 1 1 0 BTK motif Acetyltransf_1 PF00583.19 EGO60206.1 - 9.6e-16 57.5 0.1 1.5e-15 56.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGO60206.1 - 5.2e-07 29.3 0.1 9.5e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGO60206.1 - 0.0006 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGO60206.1 - 0.0029 17.7 0.0 0.0052 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGO60206.1 - 0.0053 16.6 0.1 0.01 15.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGO60206.1 - 0.042 14.0 0.0 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGO60206.1 - 0.069 13.1 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EGO60206.1 - 0.13 11.9 0.1 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase adh_short PF00106.20 EGO60207.1 - 3.9e-29 101.7 0.0 5.6e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO60207.1 - 5.4e-23 82.0 0.4 7.7e-22 78.2 0.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO60207.1 - 6.2e-13 48.8 0.0 9.6e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO60207.1 - 3.9e-06 26.4 0.0 2.4e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family G-patch PF01585.18 EGO60208.1 - 1.8e-10 40.4 0.7 3.9e-10 39.3 0.5 1.6 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EGO60208.1 - 0.0005 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGO60208.1 - 0.0092 15.6 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1049 PF06305.6 EGO60209.1 - 0.0053 16.1 0.2 0.0066 15.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) OEP PF02321.13 EGO60209.1 - 0.011 15.2 0.4 0.013 15.1 0.3 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein DUF2681 PF10883.3 EGO60209.1 - 0.019 15.1 0.8 0.021 15.0 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) PHO4 PF01384.15 EGO60209.1 - 0.059 12.0 0.0 0.059 12.0 0.0 1.0 1 0 0 1 1 1 0 Phosphate transporter family Mito_carr PF00153.22 EGO60210.1 - 2.9e-69 228.8 5.6 1.4e-23 82.3 0.2 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.11 EGO60211.1 - 3.9e-46 155.1 0.4 4.5e-46 154.9 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Anp1 PF03452.9 EGO60212.1 - 2.9e-111 370.9 0.0 3.6e-111 370.6 0.0 1.1 1 0 0 1 1 1 1 Anp1 HhH-GPD PF00730.20 EGO60213.1 - 1.9e-15 57.0 0.0 5.2e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ecm33 PF12454.3 EGO60215.1 - 2.8e-15 55.8 3.2 7.6e-15 54.5 2.2 1.8 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 EGO60215.1 - 6.6e-10 38.9 3.1 0.12 12.3 0.0 5.0 1 1 2 4 4 4 4 Receptor L domain LRR_5 PF13306.1 EGO60215.1 - 0.0068 16.1 2.2 0.041 13.5 0.0 2.5 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) AMP-binding PF00501.23 EGO60216.1 - 2e-84 283.4 0.0 2.6e-84 283.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO60216.1 - 1.4e-15 58.0 0.1 3.7e-15 56.6 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EGO60216.1 - 0.00022 19.8 0.0 0.0098 14.4 0.0 2.1 2 0 0 2 2 2 2 GH3 auxin-responsive promoter R-HINP1I PF11463.3 EGO60216.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease Methyltransf_23 PF13489.1 EGO60217.1 - 6.9e-12 45.3 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO60217.1 - 5.4e-07 30.0 0.0 2.3e-06 27.9 0.0 2.1 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO60217.1 - 0.00013 21.6 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO60217.1 - 0.0072 16.7 0.0 0.02 15.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO60217.1 - 0.083 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NAAA-beta PF15508.1 EGO60217.1 - 0.088 13.1 0.1 0.24 11.7 0.1 1.7 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Methyltransf_26 PF13659.1 EGO60217.1 - 0.15 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AhpC-TSA PF00578.16 EGO60218.1 - 9.2e-24 83.4 0.0 2e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGO60218.1 - 1.4e-16 60.3 0.0 3.2e-16 59.1 0.0 1.6 1 1 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EGO60218.1 - 0.006 16.4 0.0 0.024 14.5 0.0 2.0 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Yae1_N PF09811.4 EGO60220.1 - 3.8e-10 39.1 6.0 7.5e-10 38.1 4.2 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF1943 PF09172.6 EGO60220.1 - 1.6 7.5 5.4 0.75 8.6 2.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) DUF1098 PF06497.6 EGO60220.1 - 1.8 8.7 5.4 1.6 8.8 2.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1098) Nucleo_P87 PF07267.6 EGO60220.1 - 2.3 6.8 8.6 2.9 6.4 5.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 OB_NTP_bind PF07717.11 EGO60221.1 - 6.7e-24 83.9 0.0 1.5e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGO60221.1 - 3e-23 81.7 0.1 3e-23 81.7 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) DnaJ PF00226.26 EGO60222.1 - 1.3e-26 92.0 3.1 2.6e-26 91.1 2.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EGO60222.1 - 2.3e-16 59.6 17.1 3.6e-16 58.9 11.8 1.3 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EGO60222.1 - 1.6e-15 56.7 0.0 1.9e-12 46.8 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain HypA PF01155.14 EGO60222.1 - 0.0042 16.7 8.6 0.085 12.5 0.6 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EGO60222.1 - 5.8 6.8 13.0 50 3.8 9.1 2.1 1 1 0 1 1 1 0 Double zinc ribbon FA_desaturase PF00487.19 EGO60223.1 - 3.6e-31 108.5 19.0 5.2e-31 108.0 13.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EGO60223.1 - 2.4e-20 71.4 0.1 4.2e-20 70.7 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) ATG2_CAD PF13329.1 EGO60224.1 - 3.6e-48 163.0 0.3 8.8e-48 161.8 0.2 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EGO60224.1 - 6.5e-30 103.1 0.2 1.7e-29 101.8 0.1 1.8 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 EGO60224.1 - 0.027 14.0 0.5 0.13 11.8 0.1 2.2 2 0 0 2 2 2 0 N-terminal region of Chorein, a TM vesicle-mediated sorter Amino_oxidase PF01593.19 EGO60225.1 - 4.2e-43 148.0 1.2 2.5e-33 115.8 0.1 3.1 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGO60225.1 - 4.2e-15 55.5 0.1 8.9e-15 54.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGO60225.1 - 1.6e-06 28.4 0.4 1.1e-05 25.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGO60225.1 - 1e-05 24.6 0.0 0.00025 20.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO60225.1 - 2.3e-05 24.5 0.1 0.00014 21.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGO60225.1 - 0.00036 19.1 0.1 0.11 10.9 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EGO60225.1 - 0.00044 20.1 0.1 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO60225.1 - 0.00046 19.9 0.2 0.058 13.1 0.1 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EGO60225.1 - 0.00054 19.1 0.6 0.00081 18.5 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EGO60225.1 - 0.0032 16.6 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EGO60225.1 - 0.005 15.7 0.3 0.012 14.4 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 EGO60225.1 - 0.061 12.8 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EGO60225.1 - 0.18 11.4 0.1 0.36 10.4 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acyl-CoA_dh_1 PF00441.19 EGO60226.1 - 2.4e-35 121.8 0.4 3.5e-35 121.3 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EGO60226.1 - 1.1e-20 73.1 0.0 2.4e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EGO60226.1 - 8.9e-17 60.3 0.5 1.8e-16 59.3 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EGO60226.1 - 1.6e-08 35.1 0.3 1.2e-07 32.2 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGO60226.1 - 0.054 13.7 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain SAE2 PF08573.5 EGO60228.1 - 1.3e-27 96.3 1.8 4.6e-27 94.5 0.0 2.8 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus bZIP_1 PF00170.16 EGO60228.1 - 1.6 8.7 11.6 0.71 9.8 0.7 3.5 3 0 0 3 3 3 0 bZIP transcription factor DUF972 PF06156.8 EGO60228.1 - 2.5 8.4 5.5 22 5.4 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) UCH PF00443.24 EGO60229.1 - 8e-51 172.7 0.0 1.5e-50 171.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO60229.1 - 1.6e-17 63.8 0.0 4.2e-17 62.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HAD_2 PF13419.1 EGO60230.1 - 7.5e-15 55.5 0.0 4.4e-14 53.0 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO60230.1 - 0.0017 18.0 0.0 0.0034 17.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like SR-25 PF10500.4 EGO60230.1 - 0.34 10.3 3.2 0.49 9.8 2.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_L18p PF00861.17 EGO60231.1 - 7.7e-43 145.4 0.2 1.5e-42 144.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EGO60231.1 - 5.2e-33 113.4 5.5 5.2e-33 113.4 3.8 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region LRR_6 PF13516.1 EGO60233.1 - 2.2e-06 27.1 8.6 19 5.7 0.0 8.6 9 0 0 9 9 9 1 Leucine Rich repeat LRR_1 PF00560.28 EGO60233.1 - 0.0053 16.6 1.3 37 4.8 0.0 6.5 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_4 PF12799.2 EGO60233.1 - 0.0079 15.7 0.3 0.0079 15.7 0.2 4.9 6 2 0 6 6 6 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO60233.1 - 0.14 11.9 5.4 0.093 12.5 0.4 3.1 3 1 0 3 3 3 0 Leucine rich repeat FAM60A PF15396.1 EGO60233.1 - 0.25 11.0 6.7 0.58 9.8 4.6 1.6 1 0 0 1 1 1 0 Protein Family FAM60A RNase_H2-Ydr279 PF09468.5 EGO60233.1 - 0.75 8.9 7.3 1.5 7.9 5.1 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Plasmodium_Vir PF05795.6 EGO60233.1 - 1.9 7.5 4.1 3.7 6.6 2.8 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein zf-UBR PF02207.15 EGO60234.1 - 1e-16 60.3 3.1 1e-16 60.3 2.1 2.8 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) DUF572 PF04502.8 EGO60234.1 - 0.00073 18.8 0.7 0.00073 18.8 0.5 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF572) Mucin PF01456.12 EGO60234.1 - 0.015 15.0 16.8 0.05 13.3 11.6 1.9 1 0 0 1 1 1 0 Mucin-like glycoprotein Red1 PF07964.6 EGO60234.1 - 2.5 6.1 10.3 3.8 5.5 7.2 1.1 1 0 0 1 1 1 0 Rec10 / Red1 MCM PF00493.18 EGO60235.1 - 2.6e-138 460.3 0.1 3.8e-138 459.8 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EGO60235.1 - 1.7e-28 99.6 31.4 1.7e-28 99.6 21.8 2.4 3 1 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EGO60235.1 - 7.4e-21 74.8 0.1 1.8e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGO60235.1 - 1.2e-07 31.1 0.1 5.7e-06 25.6 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGO60235.1 - 3.3e-06 26.8 0.0 6.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EGO60235.1 - 0.0033 16.9 0.2 0.018 14.4 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EGO60235.1 - 0.005 16.4 0.0 0.04 13.5 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) zf-TFIIB PF13453.1 EGO60235.1 - 0.052 12.7 1.2 0.14 11.3 0.8 1.8 1 0 0 1 1 1 0 Transcription factor zinc-finger AAA_32 PF13654.1 EGO60235.1 - 0.11 11.1 1.4 0.22 10.1 0.0 2.1 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.20 EGO60236.1 - 1e-42 146.1 0.0 2.2e-42 145.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO60236.1 - 2.2e-21 76.1 0.0 5.9e-21 74.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO60236.1 - 0.043 12.7 0.0 0.11 11.4 0.0 1.6 1 1 0 1 1 1 0 Kinase-like DUF4488 PF14869.1 EGO60236.1 - 0.25 10.9 0.0 0.42 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) Med1 PF10744.4 EGO60237.1 - 3.7e-36 124.7 0.0 1.2e-35 123.0 0.0 1.8 2 1 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 DUF2528 PF10800.3 EGO60238.1 - 0.00015 22.1 0.4 0.00037 20.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2528) SPATA24 PF15175.1 EGO60238.1 - 0.01 15.5 1.0 0.01 15.5 0.7 2.2 2 1 0 2 2 2 0 Spermatogenesis-associated protein 24 THOC7 PF05615.8 EGO60238.1 - 2.6 8.3 13.4 1.2 9.4 6.5 2.4 1 1 2 3 3 3 0 Tho complex subunit 7 FlgN PF05130.7 EGO60238.1 - 3.4 7.9 20.8 0.03 14.5 3.1 3.1 2 1 1 3 3 3 0 FlgN protein ParB PF08775.5 EGO60238.1 - 6.8 7.0 8.3 0.91 9.8 0.8 2.7 2 1 1 3 3 3 0 ParB family Fib_alpha PF08702.5 EGO60238.1 - 9.7 6.3 9.8 2.5 8.2 0.8 3.1 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Amidohydro_4 PF13147.1 EGO60239.1 - 1e-07 32.2 0.3 1.5e-07 31.7 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 EGO60239.1 - 0.00018 21.1 0.0 0.00039 20.0 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EGO60239.1 - 0.00028 20.6 0.2 0.00041 20.1 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family NAD_binding_6 PF08030.7 EGO60239.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain MFS_1 PF07690.11 EGO60240.1 - 2.5e-32 111.9 54.3 3.9e-32 111.3 37.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO60240.1 - 4e-08 32.2 17.0 4e-08 32.2 11.8 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MRC1 PF09444.5 EGO60241.1 - 4.4e-44 150.3 17.9 4.4e-44 150.3 12.4 8.4 5 3 2 8 8 8 1 MRC1-like domain PRP1_N PF06424.7 EGO60241.1 - 0.0054 17.0 1.2 0.0054 17.0 0.8 7.5 4 2 1 5 5 5 2 PRP1 splicing factor, N-terminal SAGA-Tad1 PF12767.2 EGO60242.1 - 5.1e-60 203.2 0.0 6.6e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit GDH_N PF12466.3 EGO60242.1 - 0.12 12.4 0.1 0.93 9.5 0.0 2.3 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal Spc97_Spc98 PF04130.8 EGO60243.1 - 4.8e-123 411.3 0.0 5.9e-123 411.0 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DHO_dh PF01180.16 EGO60244.1 - 4.6e-19 68.4 0.0 1.4e-18 66.8 0.0 1.8 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase RNA_Me_trans PF04252.8 EGO60245.1 - 3.3e-51 173.4 0.0 3.8e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.17 EGO60246.1 - 1e-113 380.6 0.0 1.4e-113 380.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EGO60246.1 - 0.0011 18.8 0.0 0.0054 16.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family CIAPIN1 PF05093.8 EGO60247.1 - 3.6e-35 120.0 2.6 5.4e-35 119.4 1.8 1.2 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis HABP4_PAI-RBP1 PF04774.10 EGO60248.1 - 0.0077 16.7 2.5 0.014 15.8 1.7 1.5 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family Formyl_trans_N PF00551.14 EGO60249.1 - 3.3e-19 69.1 0.0 6.2e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase WD40 PF00400.27 EGO60250.1 - 1.8e-70 230.4 6.2 1.3e-10 40.6 0.0 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGO60250.1 - 7.2e-06 24.4 2.6 0.03 12.4 0.3 4.6 3 2 0 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EGO60250.1 - 0.018 13.3 0.0 0.15 10.3 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain TPR_MLP1_2 PF07926.7 EGO60250.1 - 1 9.0 4.9 1.5 8.5 3.4 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein MFS_1 PF07690.11 EGO60251.1 - 4e-13 48.8 15.3 4e-13 48.8 10.6 4.3 3 2 1 4 4 4 3 Major Facilitator Superfamily AAA_17 PF13207.1 EGO60252.1 - 4.5e-10 40.4 0.1 1.8e-08 35.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGO60252.1 - 2.5e-08 34.3 0.0 3e-06 27.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 EGO60252.1 - 5.3e-05 22.8 0.0 8.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 EGO60252.1 - 0.00026 20.9 0.1 0.0007 19.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGO60252.1 - 0.00033 19.7 0.0 0.00056 19.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NB-ARC PF00931.17 EGO60252.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain T2SE PF00437.15 EGO60252.1 - 0.0013 17.7 0.0 0.0024 16.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 EGO60252.1 - 0.0017 17.4 0.0 0.0035 16.4 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin Thymidylate_kin PF02223.12 EGO60252.1 - 0.0039 16.5 0.0 0.047 13.0 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.1 EGO60252.1 - 0.005 16.8 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGO60252.1 - 0.0067 16.1 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EGO60252.1 - 0.0068 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.13 EGO60252.1 - 0.0073 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase MobB PF03205.9 EGO60252.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 EGO60252.1 - 0.022 13.9 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.13 EGO60252.1 - 0.024 14.1 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sulfotransfer_3 PF13469.1 EGO60252.1 - 0.052 14.4 0.0 0.069 14.0 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase family AAA_16 PF13191.1 EGO60252.1 - 0.06 13.3 0.1 0.099 12.6 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.15 EGO60252.1 - 0.065 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.22 EGO60252.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 EGO60252.1 - 0.069 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 EGO60252.1 - 0.073 12.5 0.1 0.32 10.4 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EGO60252.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 EGO60252.1 - 0.082 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGO60252.1 - 0.083 12.6 0.1 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EGO60252.1 - 0.094 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGO60252.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 NTPase PRELI PF04707.9 EGO60254.1 - 6.7e-43 145.9 0.2 8e-43 145.7 0.2 1.1 1 0 0 1 1 1 1 PRELI-like family Peptidase_M24 PF00557.19 EGO60255.1 - 1.5e-47 161.8 0.2 1.9e-47 161.5 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Med3 PF11593.3 EGO60255.1 - 0.15 11.2 3.0 0.21 10.7 2.1 1.3 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal DnaJ PF00226.26 EGO60256.1 - 1.9e-21 75.5 1.7 3.2e-21 74.8 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.17 EGO60257.1 - 3.4e-65 220.0 7.6 3.8e-65 219.9 5.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin Asn_synthase PF00733.16 EGO60258.1 - 5.8e-69 232.4 0.0 7.9e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGO60258.1 - 6e-37 126.1 0.0 9.4e-37 125.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGO60258.1 - 2.2e-28 98.8 0.0 5.3e-28 97.6 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EGO60258.1 - 4.8e-08 32.4 0.0 8.4e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 EGO60258.1 - 0.00039 19.3 0.0 0.002 17.0 0.0 1.9 1 1 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 EGO60258.1 - 0.00074 18.3 0.0 0.44 9.2 0.0 3.0 1 1 2 3 3 3 1 Glutamine amidotransferases class-II UQ_con PF00179.21 EGO60259.1 - 7.1e-50 168.0 0.1 7.9e-50 167.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO60259.1 - 3.6e-05 23.5 0.0 4.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGO60259.1 - 0.029 14.2 1.9 0.07 13.0 1.3 1.9 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.7 EGO60260.1 - 7.2e-74 248.5 13.8 7.2e-74 248.5 9.6 1.5 1 1 0 1 1 1 1 Pex19 protein family DUF515 PF04415.7 EGO60260.1 - 0.045 12.0 3.9 0.025 12.8 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF515) Peptidase_S46 PF10459.4 EGO60260.1 - 0.13 10.6 4.1 0.19 10.1 2.8 1.1 1 0 0 1 1 1 0 Peptidase S46 FliE PF02049.13 EGO60260.1 - 1.3 9.1 7.7 1.9 8.6 2.0 3.1 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE GET2 PF08690.5 EGO60260.1 - 2.5 7.2 8.6 0.37 9.9 2.9 1.9 1 1 1 2 2 2 0 GET complex subunit GET2 SCIMP PF15050.1 EGO60261.1 - 0.028 14.2 0.0 0.079 12.8 0.0 1.7 1 0 0 1 1 1 0 SCIMP protein DHquinase_I PF01487.10 EGO60262.1 - 6.6e-57 192.7 0.0 8.8e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.13 EGO60263.1 - 5.5e-26 90.9 0.0 1e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cucumo_coat PF00760.13 EGO60263.1 - 0.038 12.9 0.0 0.3 9.9 0.0 2.1 2 0 0 2 2 2 0 Cucumovirus coat protein COPIIcoated_ERV PF07970.7 EGO60265.1 - 1.2e-36 126.4 0.3 1.7e-36 125.9 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EGO60265.1 - 1.8e-21 75.8 0.0 2.9e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Aminotran_4 PF01063.14 EGO60266.1 - 9.5e-23 80.8 0.0 1.3e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Gifsy-2 PF13856.1 EGO60268.1 - 0.00066 19.7 0.1 0.00078 19.5 0.1 1.1 1 0 0 1 1 1 1 ATP-binding sugar transporter from pro-phage CTP_transf_2 PF01467.21 EGO60270.1 - 6.7e-16 58.7 0.0 3.6e-13 49.8 0.0 3.1 2 1 0 2 2 2 2 Cytidylyltransferase WD40 PF00400.27 EGO60271.1 - 1.4e-22 78.6 0.1 0.00079 19.2 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat FliO PF04347.8 EGO60271.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO Med3 PF11593.3 EGO60272.1 - 0.11 11.6 0.1 0.3 10.2 0.2 1.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF4633 PF15464.1 EGO60274.1 - 0.02 14.7 0.0 0.02 14.7 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4633) Prominin PF05478.6 EGO60274.1 - 0.022 12.3 1.4 0.033 11.7 0.9 1.2 1 0 0 1 1 1 0 Prominin TFIIA PF03153.8 EGO60274.1 - 0.029 14.2 13.9 0.045 13.6 9.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SseC PF04888.7 EGO60274.1 - 0.035 13.4 0.2 0.064 12.5 0.1 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Paramyxo_NS_C PF02725.9 EGO60274.1 - 0.058 13.0 3.5 0.19 11.3 2.4 1.9 1 0 0 1 1 1 0 Non-structural protein C DUF948 PF06103.6 EGO60274.1 - 2.1 8.2 7.8 1.8 8.4 0.3 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) SMAP PF15477.1 EGO60274.1 - 5.6 7.3 6.6 16 5.8 0.3 3.3 2 2 0 2 2 2 0 Small acidic protein family WD40 PF00400.27 EGO60278.1 - 5.4e-48 159.2 14.7 1.9e-11 43.3 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EGO60278.1 - 2.2e-07 29.3 3.2 0.47 8.5 0.1 4.9 3 2 1 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EGO60278.1 - 0.00027 20.7 0.2 0.025 14.3 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 EGO60278.1 - 0.004 15.4 0.0 0.01 14.0 0.0 1.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 EGO60278.1 - 0.049 12.3 0.2 1.3 7.6 0.0 2.9 1 1 1 2 2 2 0 Nup133 N terminal like DUF4444 PF14563.1 EGO60278.1 - 0.36 10.2 1.3 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4444) Aconitase PF00330.15 EGO60279.1 - 2.3e-150 501.1 0.0 5.5e-150 499.9 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGO60279.1 - 1.1e-38 132.2 0.0 2.1e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Pkinase PF00069.20 EGO60280.1 - 5.1e-11 42.2 0.0 1.4e-10 40.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO60280.1 - 1.8e-07 30.5 0.0 4.9e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT PF02985.17 EGO60280.1 - 6.2e-07 28.9 0.3 0.052 13.6 0.0 5.1 4 1 1 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 EGO60280.1 - 0.0032 17.8 0.0 3.4 8.2 0.0 3.1 2 0 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.1 EGO60280.1 - 0.0038 17.4 0.0 0.73 10.1 0.0 3.6 2 1 1 3 3 3 2 HEAT repeats Kinase-like PF14531.1 EGO60280.1 - 0.041 12.8 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like GHMP_kinases_N PF00288.21 EGO60282.1 - 2.2e-12 46.8 0.0 4.8e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGO60282.1 - 3e-07 30.5 0.0 6.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Rad52_Rad22 PF04098.10 EGO60284.1 - 6.5e-63 211.0 0.1 1.1e-62 210.3 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Cut8_C PF08559.5 EGO60285.1 - 6.5e-46 155.7 0.0 8.5e-46 155.3 0.0 1.1 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EGO60285.1 - 2.1e-18 65.8 0.6 4.5e-18 64.7 0.4 1.6 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 EGO60285.1 - 3.3e-13 49.4 1.3 5.5e-13 48.6 0.9 1.4 1 0 0 1 1 1 1 Cut8 proteasome-binding domain RRM_1 PF00076.17 EGO60286.1 - 7.9e-19 67.0 0.0 1.4e-12 47.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO60286.1 - 2.2e-18 65.9 0.0 1e-10 41.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO60286.1 - 1.3e-05 24.9 0.1 0.36 10.7 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ZZ PF00569.12 EGO60287.1 - 1.3e-14 53.4 65.7 5.7e-07 28.9 6.4 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type Peptidase_M36 PF02128.10 EGO60287.1 - 0.035 12.9 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) DMPK_coil PF08826.5 EGO60287.1 - 0.44 10.4 4.3 0.4 10.6 0.0 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like UPF0052 PF01933.13 EGO60288.1 - 4.5e-34 118.1 0.0 5.3e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Btz PF09405.5 EGO60290.1 - 3.9e-31 107.8 1.8 8.6e-31 106.6 1.3 1.6 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Asp PF00026.18 EGO60292.1 - 4.4e-65 220.0 0.8 5.9e-65 219.5 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGO60292.1 - 2.8e-11 43.6 0.0 1.2e-10 41.5 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGO60292.1 - 3.4e-05 24.2 1.0 0.33 11.4 0.2 2.9 2 1 0 2 2 2 2 Aspartyl protease NKWYS PF10364.4 EGO60292.1 - 0.079 12.6 0.2 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein AhpC-TSA_2 PF13911.1 EGO60293.1 - 1e-21 77.0 0.0 3.3e-21 75.3 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EGO60293.1 - 7.6e-05 22.3 0.0 0.00022 20.9 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGO60293.1 - 0.0019 17.7 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 Redoxin DUF1183 PF06682.7 EGO60294.1 - 1.1e-05 25.2 1.5 0.011 15.3 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1183) Zip PF02535.17 EGO60294.1 - 0.0082 15.1 0.0 0.078 11.9 0.8 1.8 1 1 1 2 2 2 1 ZIP Zinc transporter Glyco_hydro_32N PF00251.15 EGO60296.1 - 2.4e-73 247.2 4.9 3.3e-73 246.7 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EGO60296.1 - 2.7e-13 50.0 0.0 7.1e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal zf-MYND PF01753.13 EGO60297.1 - 1.2e-10 41.0 8.0 1.9e-10 40.4 5.5 1.3 1 0 0 1 1 1 1 MYND finger CDC48_N PF02359.13 EGO60297.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain 2OG-FeII_Oxy_3 PF13640.1 EGO60298.1 - 1.8e-08 34.7 0.0 3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EGO60298.1 - 0.0096 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC1 PF03109.11 EGO60299.1 - 2e-29 101.9 0.0 3.6e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family IFRD PF05004.8 EGO60302.1 - 1.9e-33 115.9 3.3 2.4e-33 115.5 2.3 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.1 EGO60302.1 - 0.00057 20.2 1.7 2.7 8.6 0.0 4.1 3 1 1 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.1 EGO60302.1 - 0.01 16.1 3.7 0.014 15.6 0.7 2.5 1 1 1 2 2 2 0 HEAT repeats Corona_nucleoca PF00937.13 EGO60302.1 - 1.5 7.7 5.6 0.27 10.1 1.2 1.6 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein FHA PF00498.21 EGO60304.1 - 4.6e-14 52.2 0.0 1.6e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 FHA domain Coiled PF05710.7 EGO60304.1 - 0.31 11.5 1.8 0.73 10.3 1.2 1.5 1 0 0 1 1 1 0 Coiled coil zf-CCCH PF00642.19 EGO60305.1 - 0.0061 16.2 2.6 0.011 15.3 1.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGO60305.1 - 0.13 12.3 7.7 0.011 15.6 2.2 1.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Herpes_UL16 PF03044.9 EGO60305.1 - 5.6 5.8 5.7 18 4.2 1.9 2.6 2 0 0 2 2 2 0 Herpesvirus UL16/UL94 family Sec1 PF00995.18 EGO60307.1 - 1.8e-151 505.6 0.0 2.1e-151 505.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Chitin_synth_1 PF01644.12 EGO60308.1 - 1.5e-81 271.9 0.4 2.2e-81 271.4 0.3 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EGO60308.1 - 1.3e-32 111.3 0.0 2.9e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EGO60308.1 - 4.3e-23 81.5 2.6 5.6e-17 61.3 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EGO60308.1 - 4.3e-07 29.9 0.0 1.6e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGO60308.1 - 8e-07 28.9 10.5 1.7e-05 24.5 7.3 2.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Abhydrolase_9_N PF15420.1 EGO60308.1 - 0.44 10.2 10.0 0.14 11.8 3.9 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF3989 PF13150.1 EGO60308.1 - 5.5 6.5 8.8 13 5.2 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3989) DUF3602 PF12223.3 EGO60309.1 - 2.7e-19 69.3 16.8 1.9e-16 60.1 1.3 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Actin PF00022.14 EGO60310.1 - 9.5e-133 442.4 0.0 1.1e-132 442.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGO60310.1 - 0.018 13.6 0.0 1.9 6.9 0.0 2.5 2 1 0 2 2 2 0 MreB/Mbl protein Aminotran_4 PF01063.14 EGO60311.1 - 2.6e-24 85.9 0.0 4.1e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV TPR_11 PF13414.1 EGO60312.1 - 3.7e-55 183.4 24.3 1.6e-14 53.2 0.5 6.7 4 2 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 EGO60312.1 - 1.1e-46 154.5 27.6 1.2e-06 27.8 0.1 11.3 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 EGO60312.1 - 1.7e-41 136.7 25.4 1.5e-05 24.5 0.0 11.4 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.1 EGO60312.1 - 3.4e-29 100.8 16.6 6.1e-08 33.1 0.1 6.9 6 1 1 7 7 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 EGO60312.1 - 7.7e-25 86.6 24.2 1.8e-06 27.7 0.3 7.6 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 EGO60312.1 - 2.1e-23 80.5 13.3 0.0022 18.0 0.1 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGO60312.1 - 1.5e-16 59.4 15.4 0.0017 18.8 0.0 9.4 5 3 4 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 EGO60312.1 - 2.5e-15 54.9 18.6 0.0081 15.8 0.2 9.9 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 EGO60312.1 - 6.7e-14 51.4 11.5 0.016 15.0 0.1 6.9 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGO60312.1 - 2.9e-13 49.9 23.6 3e-05 24.2 1.3 6.7 5 1 3 8 8 7 4 Tetratricopeptide repeat Apc3 PF12895.2 EGO60312.1 - 2.9e-12 46.5 15.8 0.00047 20.2 0.2 5.6 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EGO60312.1 - 1.4e-11 43.2 15.7 0.27 11.1 0.0 8.5 8 1 1 9 9 9 4 Tetratricopeptide repeat SHNi-TPR PF10516.4 EGO60312.1 - 1.6e-05 24.0 5.2 0.88 8.8 0.0 5.6 6 0 0 6 6 6 2 SHNi-TPR TPR_6 PF13174.1 EGO60312.1 - 0.00048 20.4 18.6 25 5.5 0.0 9.2 9 1 0 9 9 8 0 Tetratricopeptide repeat DUF2561 PF10812.3 EGO60312.1 - 0.0023 17.5 0.7 0.0047 16.5 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) MAS20 PF02064.10 EGO60312.1 - 0.018 14.9 6.3 1.6 8.6 0.1 4.2 4 2 0 4 4 4 0 MAS20 protein import receptor BLVR PF06375.6 EGO60312.1 - 0.026 14.3 7.2 0.018 14.8 3.1 2.0 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) TPR_10 PF13374.1 EGO60312.1 - 0.033 14.1 15.4 4.1 7.4 0.3 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat Sel1 PF08238.7 EGO60312.1 - 0.6 10.8 5.6 12 6.6 0.1 4.4 3 0 0 3 3 3 0 Sel1 repeat NARP1 PF12569.3 EGO60312.1 - 2.6 6.6 27.2 0.27 9.9 0.1 4.4 4 1 1 5 5 5 0 NMDA receptor-regulated protein 1 Apc5 PF12862.2 EGO60312.1 - 4.4 7.2 12.5 30 4.5 0.0 5.4 3 2 2 5 5 4 0 Anaphase-promoting complex subunit 5 TPR_3 PF07720.7 EGO60312.1 - 5 7.0 17.0 12 5.8 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat SNARE PF05739.14 EGO60313.1 - 1e-12 47.5 5.9 1e-12 47.5 4.1 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EGO60313.1 - 4.8e-08 33.0 0.8 4.8e-08 33.0 0.6 2.3 2 1 0 2 2 2 1 Syntaxin ETRAMP PF09716.5 EGO60313.1 - 0.0016 18.3 0.1 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Synaptobrevin PF00957.16 EGO60313.1 - 0.016 14.8 2.8 0.05 13.1 0.4 2.4 2 0 0 2 2 2 0 Synaptobrevin RasGAP_C PF03836.10 EGO60313.1 - 0.69 9.6 7.7 0.13 11.9 0.9 2.6 2 1 1 3 3 3 0 RasGAP C-terminus Laminin_II PF06009.7 EGO60313.1 - 1.2 8.9 8.7 0.46 10.2 1.6 2.7 2 1 1 3 3 3 0 Laminin Domain II DivIVA PF05103.8 EGO60313.1 - 1.7 8.7 10.6 0.4 10.7 0.4 2.8 2 2 1 3 3 3 0 DivIVA protein Brix PF04427.13 EGO60315.1 - 3.2e-47 160.6 0.4 4e-47 160.3 0.2 1.1 1 0 0 1 1 1 1 Brix domain RRM_1 PF00076.17 EGO60317.1 - 4.3e-38 128.7 0.5 6.8e-19 67.2 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO60317.1 - 1.1e-28 99.0 0.2 4.6e-13 48.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO60317.1 - 5e-13 48.6 0.1 1.4e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGO60317.1 - 2.1e-06 27.3 0.1 0.015 15.0 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EGO60317.1 - 0.018 14.7 0.1 4.5 7.0 0.0 2.2 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EGO60317.1 - 0.025 14.4 0.0 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif OB_RNB PF08206.6 EGO60317.1 - 0.03 13.8 0.5 4.8 6.7 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF4651 PF15513.1 EGO60317.1 - 0.06 12.7 0.1 6.5 6.2 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4651) SHNi-TPR PF10516.4 EGO60318.1 - 1e-14 53.4 0.2 1e-14 53.4 0.1 2.9 3 0 0 3 3 3 1 SHNi-TPR TPR_3 PF07720.7 EGO60318.1 - 9.9e-08 31.6 6.5 2.8e-07 30.2 4.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGO60318.1 - 1.2e-05 25.1 14.9 2.8e-05 23.9 1.2 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO60318.1 - 1.3e-05 25.4 1.7 1.3e-05 25.4 1.2 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO60318.1 - 1.4e-05 25.5 3.1 1.4e-05 25.5 2.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGO60318.1 - 4.4e-05 23.0 11.0 4.6e-05 22.9 1.6 3.3 3 0 0 3 3 3 1 TPR repeat TPR_10 PF13374.1 EGO60318.1 - 0.025 14.5 0.7 0.025 14.5 0.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EGO60318.1 - 0.059 13.5 3.0 0.093 12.9 0.0 2.9 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGO60318.1 - 0.7 10.6 10.3 0.19 12.4 2.5 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGO60318.1 - 2 8.1 6.8 5.9 6.6 4.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGO60318.1 - 2.6 8.0 5.8 0.8 9.6 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Flavoprotein PF02441.14 EGO60319.1 - 8.1e-44 148.4 0.1 1.3e-43 147.7 0.1 1.3 1 0 0 1 1 1 1 Flavoprotein p450 PF00067.17 EGO60321.1 - 1.6e-41 142.3 0.2 5.7e-28 97.6 0.1 3.0 2 1 0 2 2 2 2 Cytochrome P450 Alpha_kinase PF02816.13 EGO60322.1 - 1.2e-48 165.2 0.1 1.8e-48 164.6 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.1 EGO60322.1 - 7.9e-07 29.3 0.0 1.7e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EGO60322.1 - 0.00018 21.3 0.0 0.00041 20.1 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Rho_N PF07498.7 EGO60323.1 - 0.003 17.2 0.1 0.0055 16.4 0.1 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain FadR_C PF07840.7 EGO60323.1 - 0.022 14.3 0.1 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 FadR C-terminal domain Acyl-CoA_dh_1 PF00441.19 EGO60324.1 - 1.5e-11 44.5 0.0 2.5e-10 40.6 0.0 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGO60324.1 - 1.9e-05 24.0 0.4 0.00047 19.6 0.3 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ICL PF00463.16 EGO60325.1 - 3.7e-297 985.6 1.2 4.2e-297 985.4 0.8 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EGO60325.1 - 1.5e-12 47.2 0.0 3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase SNF2_N PF00176.18 EGO60327.1 - 3.7e-57 193.3 0.1 5.3e-57 192.8 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EGO60327.1 - 1.6e-26 91.9 1.2 5.3e-26 90.3 0.8 2.0 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EGO60327.1 - 1.2e-09 37.8 0.0 1.8e-08 34.1 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO60327.1 - 0.0037 17.1 0.1 0.031 14.0 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.1 EGO60327.1 - 0.0083 14.9 0.6 1.1 7.9 0.0 2.8 3 0 0 3 3 3 2 P-loop containing NTP hydrolase pore-1 TK PF00265.13 EGO60327.1 - 0.047 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Thymidine kinase PhyH PF05721.8 EGO60328.1 - 4.1e-66 223.0 0.0 4.8e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MRP-L20 PF12824.2 EGO60330.1 - 2.5e-55 186.9 3.8 3.1e-55 186.6 2.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 COBRA PF04833.10 EGO60330.1 - 0.025 14.3 0.5 1.3 8.7 0.1 2.1 2 0 0 2 2 2 0 COBRA-like protein FYVE PF01363.16 EGO60331.1 - 0.013 15.3 9.0 0.048 13.5 6.2 1.9 1 0 0 1 1 1 0 FYVE zinc finger Glyco_trans_2_3 PF13632.1 EGO60332.1 - 4.4e-35 121.1 5.5 4.4e-35 121.1 3.8 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGO60332.1 - 3.5e-07 30.2 0.0 4.4e-05 23.3 0.0 3.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGO60332.1 - 0.00066 19.3 0.0 0.0065 16.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EGO60332.1 - 0.017 14.4 0.3 0.13 11.4 0.2 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 21 Trehalase PF01204.13 EGO60333.1 - 6e-196 652.0 0.0 7.4e-196 651.7 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EGO60333.1 - 3.2e-17 61.5 0.4 5.2e-17 60.8 0.3 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF3405 PF11885.3 EGO60334.1 - 4.3e-210 698.1 1.5 5.5e-210 697.8 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DUF1087 PF06465.8 EGO60334.1 - 0.054 13.4 1.4 0.098 12.5 1.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) RTA1 PF04479.8 EGO60335.1 - 9.5e-54 182.2 8.5 1.4e-53 181.7 5.9 1.2 1 0 0 1 1 1 1 RTA1 like protein PalH PF08733.5 EGO60335.1 - 0.01 14.6 0.1 0.021 13.6 0.1 1.4 1 1 0 1 1 1 0 PalH/RIM21 GATase_2 PF00310.16 EGO60336.1 - 1.3e-20 73.4 0.1 2e-16 59.6 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGO60336.1 - 1e-15 57.8 0.0 1.9e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EGO60336.1 - 1.1e-15 57.5 0.0 2e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EGO60336.1 - 9.4e-12 44.7 0.2 1.7e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EGO60336.1 - 9.2e-07 27.8 0.0 1.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Cyt-b5 PF00173.23 EGO60338.1 - 1.4e-15 56.8 0.1 1.6e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MreB_Mbl PF06723.8 EGO60338.1 - 0.13 10.8 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 MreB/Mbl protein TPR_12 PF13424.1 EGO60339.1 - 1.8e-11 43.8 9.1 6.9e-05 22.7 0.0 4.2 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGO60339.1 - 2.2e-09 36.5 0.4 0.024 14.2 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGO60339.1 - 3.2e-08 32.8 1.0 0.0024 17.6 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGO60339.1 - 3.3e-07 29.8 8.3 0.034 13.7 0.2 3.7 3 0 0 3 3 3 3 TPR repeat TPR_7 PF13176.1 EGO60339.1 - 1.1e-05 24.8 6.7 0.012 15.3 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO60339.1 - 3e-05 23.4 1.6 0.3 10.9 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGO60339.1 - 0.0011 18.8 3.7 0.0061 16.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGO60339.1 - 0.19 12.2 1.0 12 6.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EGO60339.1 - 0.24 11.5 3.6 0.47 10.6 0.1 3.0 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGO60339.1 - 0.51 11.1 10.2 5.7 7.8 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat bZIP_1 PF00170.16 EGO60340.1 - 6.7e-09 35.5 5.6 6.7e-09 35.5 3.9 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EGO60340.1 - 1.2e-05 25.0 6.4 1.2e-05 25.0 4.4 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EGO60340.1 - 0.0005 20.3 8.5 0.0005 20.3 5.9 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF4585 PF15232.1 EGO60340.1 - 0.027 14.3 0.2 0.065 13.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) Kinesin-relat_1 PF12711.2 EGO60340.1 - 0.034 14.5 0.3 0.071 13.5 0.2 1.5 1 0 0 1 1 1 0 Kinesin motor Glutaredoxin2_C PF04399.8 EGO60340.1 - 0.098 12.2 0.4 0.17 11.4 0.3 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF4175 PF13779.1 EGO60340.1 - 0.15 9.7 8.1 0.19 9.3 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) IncA PF04156.9 EGO60340.1 - 1.2 8.6 8.4 2.2 7.8 5.9 1.3 1 1 0 1 1 1 0 IncA protein BCL9 PF11502.3 EGO60340.1 - 2.1 7.9 5.2 0.19 11.2 0.4 1.6 2 0 0 2 2 2 0 B-cell lymphoma 9 protein DUF4597 PF15366.1 EGO60342.1 - 0.018 14.6 0.2 0.018 14.6 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) BAF1_ABF1 PF04684.8 EGO60343.1 - 0.35 9.6 3.7 0.54 9.0 2.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MS_channel PF00924.13 EGO60344.1 - 1.2e-19 70.4 3.1 1.9e-19 69.8 2.2 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EGO60344.1 - 0.0036 16.5 0.5 0.01 15.0 0.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EGO60344.1 - 0.0092 15.2 0.1 0.025 13.9 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EGO60344.1 - 0.0093 15.7 0.0 0.051 13.4 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain DUF3671 PF12420.3 EGO60344.1 - 2.8 7.9 10.2 0.2 11.6 0.8 3.1 2 1 1 3 3 3 0 Protein of unknown function FLILHELTA PF10306.4 EGO60345.1 - 5.5e-35 119.2 0.0 8.9e-35 118.5 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA Suf PF05843.9 EGO60345.1 - 0.0077 15.9 0.3 0.01 15.5 0.2 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF1279 PF06916.8 EGO60345.1 - 0.0085 16.3 0.0 0.024 14.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) RasGEF_N_2 PF14663.1 EGO60345.1 - 0.11 12.4 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain SelP_N PF04592.9 EGO60345.1 - 0.7 9.2 4.7 1 8.6 3.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_A4 PF01828.12 EGO60346.1 - 1e-16 60.6 0.0 1.3e-15 57.0 0.0 2.5 1 1 0 1 1 1 1 Peptidase A4 family Erv26 PF04148.8 EGO60347.1 - 0.53 9.6 3.4 0.62 9.3 2.4 1.1 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 Glyco_hydro_31 PF01055.21 EGO60348.1 - 3.8e-153 510.4 4.6 5e-153 510.0 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGO60348.1 - 4.2e-25 87.3 0.1 8.6e-24 83.1 0.1 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like NDK PF00334.14 EGO60349.1 - 1.7e-55 186.5 0.0 1.9e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SPX PF03105.14 EGO60350.1 - 3.7e-66 223.7 1.4 3.7e-66 223.7 0.9 2.2 2 0 0 2 2 2 1 SPX domain EXS PF03124.9 EGO60350.1 - 2.9e-43 148.2 24.9 6.4e-25 87.9 6.1 2.1 1 1 1 2 2 2 2 EXS family FUR PF01475.14 EGO60350.1 - 0.06 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Ferric uptake regulator family DUF883 PF05957.8 EGO60350.1 - 0.44 10.9 5.0 0.33 11.3 1.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) TMEM171 PF15471.1 EGO60352.1 - 0.15 10.8 0.3 0.25 10.0 0.2 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 CAF1A PF12253.3 EGO60353.1 - 4.1e-23 81.2 2.8 4.1e-23 81.2 1.9 3.0 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EGO60353.1 - 1.2e-08 34.5 50.7 1.2e-08 34.5 35.1 2.6 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 EGO60353.1 - 0.22 10.8 43.4 0.025 13.9 20.1 2.3 2 0 0 2 2 2 0 SprA-related family U79_P34 PF03064.11 EGO60353.1 - 0.39 10.2 25.1 0.83 9.1 17.4 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Med3 PF11593.3 EGO60353.1 - 0.65 9.1 38.3 0.026 13.8 9.6 2.7 3 0 0 3 3 3 0 Mediator complex subunit 3 fungal Ycf1 PF05758.7 EGO60353.1 - 2.7 5.6 21.9 4 5.0 15.2 1.3 1 0 0 1 1 1 0 Ycf1 Spore_coat_CotO PF14153.1 EGO60353.1 - 7.2 6.0 35.8 0.17 11.3 20.0 2.0 2 0 0 2 2 2 0 Spore coat protein CotO Mitofilin PF09731.4 EGO60353.1 - 9.4 4.7 40.7 2.3 6.7 22.5 2.2 2 0 0 2 2 2 0 Mitochondrial inner membrane protein DUF3759 PF12585.3 EGO60354.1 - 1.5e-35 120.9 5.6 1.9e-35 120.6 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) GCD14 PF08704.5 EGO60355.1 - 8.4e-64 215.4 0.0 2.7e-47 161.3 0.0 3.0 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EGO60355.1 - 0.0004 20.4 0.0 0.0011 19.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO60355.1 - 0.00041 20.9 0.0 0.0037 17.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Transp_cyt_pur PF02133.10 EGO60357.1 - 9.7e-35 119.9 34.6 9.8e-34 116.6 24.0 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Peptidase_M50B PF13398.1 EGO60359.1 - 7.5e-56 188.6 16.8 1.1e-55 188.0 11.6 1.2 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 EGO60359.1 - 0.012 14.5 1.8 0.079 11.9 0.1 2.5 2 0 0 2 2 2 0 Peptidase family M50 Peptidase_M41 PF01434.13 EGO60359.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M41 ER_lumen_recept PF00810.13 EGO60359.1 - 0.58 10.6 5.4 0.15 12.5 0.7 2.2 3 1 0 3 3 3 0 ER lumen protein retaining receptor DUF3021 PF11457.3 EGO60359.1 - 3 7.7 9.0 0.24 11.2 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) UCR_Fe-S_N PF10399.4 EGO60359.1 - 4 6.6 6.1 1.3 8.2 0.0 3.0 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Peptidase_M18 PF02127.10 EGO60360.1 - 2.8e-127 424.8 0.0 3.3e-127 424.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) TMEM125 PF15109.1 EGO60360.1 - 0.064 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 TMEM125 protein family HET PF06985.6 EGO60361.1 - 4.2e-37 127.3 0.1 8.2e-37 126.4 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RAI1 PF08652.6 EGO60362.1 - 6e-30 102.8 0.0 1.1e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Tn7_Tnp_TnsA_N PF08722.6 EGO60362.1 - 0.067 13.1 0.1 17 5.4 0.0 2.5 2 0 0 2 2 2 0 TnsA endonuclease N terminal ResIII PF04851.10 EGO60362.1 - 0.075 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sec8_exocyst PF04048.9 EGO60363.1 - 1.7e-51 173.6 0.5 4.1e-51 172.3 0.3 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EGO60363.1 - 2.7e-10 39.6 2.2 5e-10 38.7 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 EGO60363.1 - 0.0029 17.3 0.3 0.0056 16.4 0.2 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 EGO60363.1 - 0.035 13.9 1.4 0.6 9.9 0.1 3.4 4 0 0 4 4 4 0 Vps51/Vps67 TPR_14 PF13428.1 EGO60363.1 - 0.79 10.5 3.7 5 8.0 0.0 3.7 4 1 1 5 5 5 0 Tetratricopeptide repeat SMI1_KNR4 PF09346.5 EGO60365.1 - 1.2e-32 112.6 0.0 2.7e-32 111.4 0.0 1.6 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) RNase_H2-Ydr279 PF09468.5 EGO60365.1 - 4.5 6.3 8.4 7.2 5.7 5.8 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) UPF0220 PF05255.6 EGO60366.1 - 6e-64 214.2 2.4 6.7e-64 214.1 1.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) MIF4G_like PF09088.6 EGO60367.1 - 5.9e-83 277.0 0.4 9.8e-83 276.2 0.3 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EGO60367.1 - 1.5e-64 217.6 0.0 2.4e-64 217.0 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 EGO60367.1 - 0.0014 18.0 0.0 0.0053 16.1 0.0 1.9 2 1 0 2 2 2 1 MIF4G domain Pkinase PF00069.20 EGO60368.1 - 2.7e-63 213.5 0.0 3.5e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO60368.1 - 1.1e-25 90.2 0.0 1.5e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO60368.1 - 6.3e-08 31.9 0.0 4.2e-07 29.1 0.0 1.9 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EGO60368.1 - 0.00025 20.8 0.2 0.0047 16.6 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGO60368.1 - 0.041 13.4 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RRM_1 PF00076.17 EGO60371.1 - 3.6e-33 113.0 0.0 5.7e-16 57.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO60371.1 - 9.6e-18 63.9 0.0 4.1e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO60371.1 - 6.7e-17 61.0 0.0 7.2e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGO60371.1 - 0.0067 16.1 0.0 2.2 8.0 0.0 2.2 2 0 0 2 2 2 2 Limkain b1 OB_RNB PF08206.6 EGO60371.1 - 0.1 12.1 0.4 4.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Tom7 PF08038.7 EGO60372.1 - 1.5e-19 69.1 0.3 1.7e-19 68.9 0.2 1.0 1 0 0 1 1 1 1 TOM7 family Mito_carr PF00153.22 EGO60373.1 - 5.2e-55 183.1 1.5 1.2e-19 69.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-H2C2_2 PF13465.1 EGO60374.1 - 9.1e-17 60.4 28.3 6.6e-08 32.4 0.8 5.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EGO60374.1 - 5e-14 51.5 22.9 0.0011 19.1 0.9 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO60374.1 - 9.6e-13 47.6 32.4 0.00025 21.1 0.1 5.6 6 0 0 6 6 6 4 Zinc finger, C2H2 type P35 PF02331.10 EGO60374.1 - 0.0038 16.4 0.1 0.007 15.5 0.0 1.3 1 0 0 1 1 1 1 Apoptosis preventing protein zf-C2H2_jaz PF12171.3 EGO60374.1 - 0.017 15.2 0.0 0.017 15.2 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGO60374.1 - 0.052 13.7 0.1 0.052 13.7 0.1 4.9 6 0 0 6 6 6 0 Zinc-finger of C2H2 type C1_4 PF07975.7 EGO60374.1 - 1.4 8.9 9.0 3.8 7.5 1.0 3.3 1 1 1 2 2 2 0 TFIIH C1-like domain Dicty_REP PF05086.7 EGO60374.1 - 1.6 6.3 6.5 2.2 5.9 4.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CHORD PF04968.7 EGO60374.1 - 3.6 7.8 15.3 2.7 8.3 1.0 3.9 3 1 1 4 4 4 0 CHORD Urm1 PF09138.6 EGO60377.1 - 5e-32 109.8 0.0 5.8e-32 109.6 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EGO60377.1 - 0.0058 17.0 0.0 0.0077 16.6 0.0 1.3 1 1 0 1 1 1 1 ThiS family WD40 PF00400.27 EGO60378.1 - 8e-53 174.5 23.6 2.6e-07 30.2 0.0 11.7 13 0 0 13 13 13 9 WD domain, G-beta repeat Lactonase PF10282.4 EGO60378.1 - 0.00049 19.2 0.1 0.0023 17.0 0.0 2.1 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller DUF3317 PF11779.3 EGO60379.1 - 1.2e-19 69.4 5.8 1.6e-19 69.0 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) RF-1 PF00472.15 EGO60380.1 - 1.8e-26 92.2 0.7 1.8e-26 92.2 0.5 1.5 2 0 0 2 2 2 1 RF-1 domain Paf1 PF03985.8 EGO60380.1 - 1.9 7.1 7.0 2.1 6.9 4.8 1.2 1 0 0 1 1 1 0 Paf1 Actin PF00022.14 EGO60381.1 - 2.9e-159 529.7 0.0 3.3e-159 529.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGO60381.1 - 0.039 14.3 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fes1 PF08609.5 EGO60382.1 - 8e-36 122.4 0.1 2.3e-35 120.9 0.0 1.8 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 Arm PF00514.18 EGO60382.1 - 2.2e-09 36.8 0.0 0.0018 18.0 0.0 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGO60382.1 - 4.4e-08 33.3 0.1 5.7e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EGO60382.1 - 3.4e-05 23.5 0.1 0.016 15.2 0.0 3.1 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 EGO60382.1 - 7e-05 23.1 0.1 0.026 15.0 0.0 3.4 2 2 2 4 4 4 2 HEAT-like repeat Peptidase_M57 PF12388.3 EGO60382.1 - 0.097 11.9 0.8 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Ribosomal_L5_C PF00673.16 EGO60383.1 - 7e-26 89.8 0.0 1e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EGO60383.1 - 0.00026 20.7 0.0 0.00043 20.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 WSC PF01822.14 EGO60384.1 - 4.6e-80 263.6 86.5 2.3e-18 65.9 8.0 6.5 6 1 1 7 7 7 5 WSC domain PAN_4 PF14295.1 EGO60384.1 - 3.4e-06 26.6 0.4 3.4e-06 26.6 0.3 6.0 7 0 0 7 7 7 1 PAN domain PAN_4 PF14295.1 EGO60385.1 - 0.00015 21.4 0.4 0.0057 16.3 0.1 2.8 2 0 0 2 2 2 1 PAN domain Glyco_hydro_16 PF00722.16 EGO60386.1 - 8e-20 70.8 0.7 2.1e-19 69.5 0.2 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 DUF3620 PF12281.3 EGO60387.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3620) Glyco_trans_2_3 PF13632.1 EGO60388.1 - 1e-45 155.8 4.0 1e-45 155.8 2.7 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 MMR_HSR1 PF01926.18 EGO60389.1 - 2.8e-17 62.7 0.2 2.6e-15 56.4 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO60389.1 - 6.6e-08 31.9 0.2 2.2e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 EGO60389.1 - 7.5e-05 21.9 0.0 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGO60389.1 - 0.002 17.9 5.1 0.031 14.1 0.0 3.3 3 0 0 3 3 3 1 Dynamin family AIG1 PF04548.11 EGO60389.1 - 0.0087 15.1 0.0 0.019 14.0 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EGO60389.1 - 0.025 15.0 0.4 0.074 13.5 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein Cytochrome-c551 PF10643.4 EGO60389.1 - 0.083 12.1 2.3 1 8.6 0.0 2.7 3 0 0 3 3 3 0 Photosystem P840 reaction-centre cytochrome c-551 TRAP_alpha PF03896.11 EGO60389.1 - 0.14 11.1 2.2 0.23 10.4 1.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit LTV PF04180.9 EGO60390.1 - 1.9e-155 518.5 13.5 2.1e-155 518.3 9.4 1.0 1 0 0 1 1 1 1 Low temperature viability protein AAA_23 PF13476.1 EGO60390.1 - 4.3 7.6 9.9 11 6.3 6.9 1.8 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.17 EGO60391.1 - 2e-19 68.9 0.0 3.1e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO60391.1 - 7.4e-16 57.8 0.0 1.1e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO60391.1 - 1.4e-12 47.3 0.0 1.9e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.22 EGO60393.1 - 5.5e-47 159.5 0.1 5.7e-27 94.6 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGO60393.1 - 6.8e-46 156.8 42.1 2e-25 89.7 12.8 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EGO60393.1 - 4.3e-07 30.1 0.2 0.93 9.4 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 EGO60393.1 - 2e-06 27.9 1.9 0.026 14.5 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain Miro PF08477.8 EGO60393.1 - 7.9e-06 26.3 0.8 0.033 14.6 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EGO60393.1 - 3e-05 23.9 0.1 0.11 12.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EGO60393.1 - 0.00019 20.8 0.6 0.55 9.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EGO60393.1 - 0.00025 20.3 3.2 1.4 8.1 0.6 3.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.1 EGO60393.1 - 0.00028 20.5 0.5 0.48 9.9 0.1 2.8 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EGO60393.1 - 0.0003 19.9 0.1 0.15 11.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 EGO60393.1 - 0.00034 19.8 1.9 0.082 12.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EGO60393.1 - 0.00099 19.4 5.1 0.25 11.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain ArgK PF03308.11 EGO60393.1 - 0.0015 17.4 2.3 0.79 8.4 0.3 2.5 2 0 0 2 2 2 2 ArgK protein AAA_25 PF13481.1 EGO60393.1 - 0.0015 17.9 0.0 0.34 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGO60393.1 - 0.0037 17.3 3.2 4.2 7.5 0.0 4.0 3 1 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EGO60393.1 - 0.0081 15.6 0.2 2.4 7.5 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain DUF87 PF01935.12 EGO60393.1 - 0.011 15.6 4.0 0.12 12.1 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 EGO60393.1 - 0.014 14.8 0.4 5.7 6.3 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 EGO60393.1 - 0.015 16.1 5.6 2.5 8.9 0.9 3.3 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 EGO60393.1 - 0.02 14.5 1.3 2.2 7.9 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EGO60393.1 - 0.057 12.3 0.1 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.7 EGO60393.1 - 0.064 12.9 0.3 0.68 9.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.13 EGO60393.1 - 0.066 12.6 0.0 5.9 6.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EGO60393.1 - 0.1 12.4 5.1 0.42 10.4 0.5 2.7 2 0 0 2 2 2 0 Dynamin family AAA_28 PF13521.1 EGO60393.1 - 0.11 12.4 1.8 0.3 11.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 EGO60393.1 - 0.13 11.7 2.4 0.31 10.4 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EGO60393.1 - 0.16 12.3 1.1 10 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EGO60393.1 - 0.16 10.9 0.0 3 6.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.4 EGO60393.1 - 0.17 10.4 4.3 1.2 7.6 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 EGO60393.1 - 0.73 9.3 2.1 11 5.4 0.2 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Fcf1 PF04900.7 EGO60395.1 - 3.4e-38 129.7 1.3 5.8e-38 129.0 0.1 1.8 2 0 0 2 2 2 1 Fcf1 Bul1_N PF04425.7 EGO60395.1 - 0.083 11.4 0.1 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Bul1 N terminus ART PF01129.13 EGO60395.1 - 0.25 10.4 0.9 18 4.3 0.0 2.2 1 1 1 2 2 2 0 NAD:arginine ADP-ribosyltransferase NmrA PF05368.8 EGO60396.1 - 4.2e-72 242.1 0.0 4.8e-72 241.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO60396.1 - 4.2e-06 26.8 0.1 4.2e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding DUF2498 PF10692.4 EGO60396.1 - 0.044 13.4 0.1 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2498) ERG2_Sigma1R PF04622.7 EGO60397.1 - 1.3e-106 354.6 0.1 1.5e-106 354.5 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein COX2-transmemb PF09125.5 EGO60397.1 - 0.21 11.1 3.0 0.29 10.6 0.7 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane EXOSC1 PF10447.4 EGO60398.1 - 3.3e-28 97.4 0.8 5.2e-28 96.8 0.5 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EGO60398.1 - 2.8e-15 55.3 0.0 5.8e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 EGO60398.1 - 0.052 13.6 0.2 0.43 10.6 0.1 2.1 1 1 0 1 1 1 0 S1 RNA binding domain Sec2p PF06428.6 EGO60399.1 - 1.4e-07 31.2 12.5 1.4e-07 31.2 8.6 3.0 2 2 1 3 3 3 1 GDP/GTP exchange factor Sec2p Atg14 PF10186.4 EGO60399.1 - 0.0014 17.6 4.7 0.0014 17.6 3.3 2.5 2 1 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin PF00261.15 EGO60399.1 - 0.03 13.4 27.4 0.031 13.3 0.3 2.7 2 1 0 2 2 2 0 Tropomyosin IncA PF04156.9 EGO60399.1 - 0.045 13.3 32.2 0.19 11.3 8.4 2.2 2 0 0 2 2 2 0 IncA protein V_ATPase_I PF01496.14 EGO60399.1 - 0.065 11.0 17.4 0.1 10.4 5.5 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3573 PF12097.3 EGO60399.1 - 0.2 10.2 11.9 0.1 11.2 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Striatin PF08232.7 EGO60399.1 - 0.27 11.5 28.8 0.11 12.8 3.1 3.2 2 1 1 3 3 3 0 Striatin family GAS PF13851.1 EGO60399.1 - 0.64 9.1 27.1 0.9 8.6 10.5 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.4 EGO60399.1 - 0.97 9.4 22.9 0.15 12.0 2.2 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 ECSIT PF06239.6 EGO60399.1 - 2 7.2 10.1 0.04 12.7 1.7 1.9 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway TFIIA PF03153.8 EGO60399.1 - 4.1 7.2 27.6 5.2 6.8 19.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EGO60399.1 - 4.8 5.2 30.6 6 4.9 21.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BLOC1_2 PF10046.4 EGO60399.1 - 5.1 7.3 15.8 0.43 10.7 2.1 3.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CorA PF01544.13 EGO60399.1 - 5.6 5.8 10.4 2.7 6.9 1.3 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Spc7 PF08317.6 EGO60399.1 - 7.4 5.1 27.7 1.7 7.2 4.4 2.3 2 1 0 2 2 2 0 Spc7 kinetochore protein TruB_N PF01509.13 EGO60400.1 - 1.4e-45 155.0 0.0 4e-45 153.6 0.0 1.7 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) Mso1_Sec1_bdg PF14475.1 EGO60402.1 - 1.1e-20 72.6 0.1 1.8e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.12 EGO60403.1 - 1.4e-31 109.3 0.8 1.4e-31 109.3 0.6 1.9 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.9 EGO60403.1 - 4e-25 87.8 36.5 1.3e-24 86.2 3.8 3.7 2 2 1 3 3 3 2 Mak16 protein C-terminal region Nop14 PF04147.7 EGO60403.1 - 0.017 13.0 34.5 0.024 12.5 23.9 1.3 1 0 0 1 1 1 0 Nop14-like family Sigma54_activ_2 PF14532.1 EGO60403.1 - 0.1 12.6 0.3 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain SGT1 PF07093.6 EGO60403.1 - 0.13 10.6 17.7 0.15 10.4 12.2 1.2 1 0 0 1 1 1 0 SGT1 protein DUF2011 PF09428.5 EGO60403.1 - 0.42 10.5 10.4 0.27 11.1 1.2 2.4 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) CDC45 PF02724.9 EGO60403.1 - 6.9 4.5 26.4 13 3.6 18.3 1.5 1 0 0 1 1 1 0 CDC45-like protein GTPase_Cys_C PF12631.2 EGO60404.1 - 8.8e-25 86.9 0.0 2.9e-24 85.2 0.0 2.0 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE TrmE_N PF10396.4 EGO60404.1 - 7.8e-22 77.3 0.0 1.7e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 EGO60404.1 - 8.4e-17 61.1 0.0 1.8e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO60404.1 - 1.8e-05 24.0 0.0 3.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGO60404.1 - 6.2e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.22 EGO60404.1 - 0.0045 17.2 0.0 0.055 13.7 0.0 2.6 3 0 0 3 3 3 1 ABC transporter DUF258 PF03193.11 EGO60404.1 - 0.02 14.1 0.1 0.046 12.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 EGO60404.1 - 0.021 15.3 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_18 PF13238.1 EGO60404.1 - 0.051 13.8 0.0 3.5 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain PEPcase PF00311.12 EGO60404.1 - 0.095 10.5 0.0 0.14 9.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase MMS19_N PF14500.1 EGO60404.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Metallophos PF00149.23 EGO60406.1 - 2.4e-08 33.6 0.5 5.1e-05 22.7 0.0 2.5 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGO60406.1 - 2.8e-06 27.2 0.9 5.2e-05 23.1 0.7 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FAM209 PF15206.1 EGO60408.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 FAM209 family DnaJ PF00226.26 EGO60409.1 - 9.9e-21 73.2 0.9 2.4e-20 72.0 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain MBOAT PF03062.14 EGO60410.1 - 5.4e-35 121.0 9.7 9e-35 120.3 6.2 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Pkinase PF00069.20 EGO60411.1 - 1e-49 169.0 0.0 1.9e-49 168.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO60411.1 - 3.3e-27 95.1 0.0 5.6e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGO60411.1 - 0.022 13.8 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGO60411.1 - 0.33 9.8 0.0 5 5.9 0.0 2.1 2 0 0 2 2 2 0 Kinase-like HSP90 PF00183.13 EGO60412.1 - 3.6e-258 857.2 33.9 4.4e-258 857.0 23.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EGO60412.1 - 4.4e-12 45.7 0.0 8.1e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGO60412.1 - 1.9e-11 43.7 0.1 1.9e-11 43.7 0.1 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 EGO60412.1 - 0.012 15.3 0.3 0.045 13.5 0.2 2.0 1 0 0 1 1 1 0 Tumour suppressor protein Peptidase_S10 PF00450.17 EGO60412.1 - 0.64 9.1 0.0 0.64 9.1 0.0 2.4 1 1 0 2 2 2 0 Serine carboxypeptidase DUF1676 PF07898.8 EGO60412.1 - 2.3 8.5 8.5 0.23 11.7 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) FKBP_C PF00254.23 EGO60414.1 - 7.9e-34 115.5 0.0 1.3e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Flavin_Reduct PF01613.13 EGO60415.1 - 1.6e-27 96.2 0.0 2.4e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain Ribosomal_L31 PF01197.13 EGO60416.1 - 0.0023 17.8 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L31 DUF3824 PF12868.2 EGO60416.1 - 1.8 9.4 11.4 0.25 12.2 2.6 2.2 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Vps5 PF09325.5 EGO60417.1 - 1.2e-88 296.3 7.7 2e-88 295.6 5.3 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EGO60417.1 - 1.7e-24 85.8 0.0 3.8e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 EGO60417.1 - 0.0069 15.6 0.7 0.024 13.9 0.2 1.9 1 1 1 2 2 2 1 WASP-binding domain of Sorting nexin protein MCP_N PF05581.7 EGO60417.1 - 0.12 12.4 0.0 24 5.1 0.0 2.3 2 0 0 2 2 2 0 Vibrio chemotaxis protein N terminus BAR PF03114.13 EGO60417.1 - 0.15 11.5 7.0 0.27 10.7 4.9 1.4 1 1 0 1 1 1 0 BAR domain Cortex-I_coil PF09304.5 EGO60417.1 - 7.6 6.6 10.9 2.9 7.9 4.5 2.4 2 1 0 2 2 2 0 Cortexillin I, coiled coil WD40 PF00400.27 EGO60418.1 - 7.3e-51 168.3 21.5 9e-09 34.8 0.3 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EGO60418.1 - 3.1e-45 153.7 0.1 4.6e-45 153.2 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 EGO60418.1 - 5.6e-07 29.0 0.0 1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 EGO60418.1 - 4.4e-06 26.5 0.0 0.0036 17.0 0.0 3.5 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EGO60418.1 - 0.0012 17.7 0.1 0.21 10.2 0.0 2.9 2 1 0 3 3 3 1 Nup133 N terminal like Nup160 PF11715.3 EGO60418.1 - 0.096 10.7 1.4 11 4.0 0.1 3.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Med11 PF10280.4 EGO60419.1 - 3.9e-47 159.0 1.0 6.3e-47 158.4 0.7 1.3 1 0 0 1 1 1 1 Mediator complex protein Peptidase_M28 PF04389.12 EGO60421.1 - 2.9e-33 115.1 0.2 4.8e-33 114.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EGO60421.1 - 0.00028 20.4 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 T2SS-T3SS_pil_N PF13629.1 EGO60421.1 - 0.19 11.2 0.3 0.49 9.9 0.2 1.6 1 0 0 1 1 1 0 Pilus formation protein N terminal region Acetyltransf_1 PF00583.19 EGO60422.1 - 4.7e-06 26.5 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGO60422.1 - 0.00011 22.2 0.1 0.00028 20.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGO60422.1 - 0.0014 18.7 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO60422.1 - 0.043 13.5 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DUF3749 PF12568.3 EGO60422.1 - 0.13 11.8 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CENP-I PF07778.6 EGO60423.1 - 5.4e-25 87.5 0.4 5.7e-25 87.4 0.3 1.0 1 0 0 1 1 1 1 Mis6 CENP-I PF07778.6 EGO60424.1 - 2.5e-17 62.3 0.5 2.7e-17 62.1 0.3 1.0 1 0 0 1 1 1 1 Mis6 G_glu_transpept PF01019.16 EGO60426.1 - 1.2e-151 505.6 0.0 1.4e-151 505.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Methyltransf_23 PF13489.1 EGO60427.1 - 7.5e-17 61.5 0.0 1.3e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGO60427.1 - 2.9e-16 59.3 0.3 1.9e-14 53.4 0.1 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EGO60427.1 - 1.7e-15 57.2 0.1 7.8e-15 55.1 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO60427.1 - 2.1e-15 56.6 0.1 4.6e-13 49.0 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO60427.1 - 4e-12 46.4 0.0 1e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO60427.1 - 9.9e-11 42.2 0.0 2.4e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO60427.1 - 4.3e-08 33.4 0.2 1.5e-07 31.7 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO60427.1 - 2.5e-06 27.5 0.0 6.1e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO60427.1 - 3.4e-06 26.3 0.3 4.5e-05 22.6 0.2 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGO60427.1 - 0.00013 21.3 0.2 0.0054 16.1 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.7 EGO60427.1 - 0.00028 20.3 0.1 0.015 14.7 0.1 2.6 2 1 1 3 3 3 1 Methionine biosynthesis protein MetW Methyltransf_PK PF05891.7 EGO60427.1 - 0.00053 19.3 0.3 0.0035 16.6 0.2 2.0 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PCMT PF01135.14 EGO60427.1 - 0.003 17.1 0.0 0.0068 15.9 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EGO60427.1 - 0.015 14.9 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EGO60427.1 - 0.027 13.6 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DOT1 PF08123.8 EGO60427.1 - 0.04 13.2 0.1 0.075 12.3 0.1 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 FtsJ PF01728.14 EGO60427.1 - 0.04 13.9 0.1 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF4471 PF14740.1 EGO60427.1 - 0.066 12.4 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) YqzE PF14038.1 EGO60427.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 YqzE-like protein GIT1_C PF12205.3 EGO60428.1 - 0.12 12.1 0.7 5 6.9 0.0 2.6 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term SecE PF00584.15 EGO60429.1 - 4e-14 51.9 0.0 4.5e-14 51.7 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Vps39_2 PF10367.4 EGO60431.1 - 4.5e-06 26.8 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 EGO60431.1 - 0.0079 15.8 0.1 0.055 13.0 0.0 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS CBM_19 PF03427.8 EGO60432.1 - 6.8 6.5 6.9 2.1 8.2 0.6 2.1 1 1 1 2 2 2 0 Carbohydrate binding domain (family 19) DUF3455 PF11937.3 EGO60434.1 - 8.1e-50 169.2 0.3 1e-49 168.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Adaptin_N PF01602.15 EGO60435.1 - 4e-145 484.1 4.0 4.9e-145 483.8 2.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EGO60435.1 - 3.2e-20 72.5 0.0 6.8e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EGO60435.1 - 1.6e-06 28.2 1.0 0.097 12.9 0.0 4.1 3 3 2 5 5 5 3 HEAT repeats Cnd1 PF12717.2 EGO60435.1 - 8.9e-06 25.6 1.9 0.0024 17.7 0.2 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EGO60435.1 - 1.2e-05 24.9 0.6 13 6.1 0.0 5.4 4 1 1 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 EGO60435.1 - 0.01 16.2 3.1 18 5.9 0.0 5.0 4 1 0 4 4 4 0 HEAT-like repeat Nipped-B_C PF12830.2 EGO60435.1 - 0.037 13.6 0.0 8.8 5.9 0.0 2.8 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus G-patch_2 PF12656.2 EGO60435.1 - 0.089 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 DExH-box splicing factor binding site Arm PF00514.18 EGO60435.1 - 0.099 12.5 2.3 31 4.5 0.0 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.5 EGO60435.1 - 0.12 11.9 3.1 0.17 11.4 0.1 2.7 3 1 0 3 3 3 0 TATA-binding protein interacting (TIP20) EF-hand_1 PF00036.27 EGO60436.1 - 2.8e-41 135.6 12.8 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGO60436.1 - 1.7e-36 124.1 5.8 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EGO60436.1 - 8.5e-35 118.1 12.2 6.8e-16 57.6 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EGO60436.1 - 1.2e-30 102.6 8.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGO60436.1 - 5.2e-26 88.7 9.7 1.4e-06 27.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EGO60436.1 - 1.3e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EGO60436.1 - 2.6e-09 36.7 1.9 0.00056 19.6 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EGO60436.1 - 1.5e-08 34.6 0.1 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EGO60436.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EGO60436.1 - 4.4e-07 29.7 2.1 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EGO60436.1 - 0.00014 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EGO60436.1 - 0.00023 20.7 0.2 0.075 12.5 0.0 2.7 1 1 1 3 3 3 1 Caleosin related protein Tenui_NCP PF04876.7 EGO60436.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EGO60436.1 - 0.0026 17.7 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 EGO60436.1 - 0.0083 16.4 1.3 2.5 8.4 0.0 2.5 1 1 2 3 3 3 2 Toprim-like DUF3349 PF11829.3 EGO60436.1 - 0.021 15.2 0.4 12 6.4 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 EGO60436.1 - 0.14 11.8 2.5 0.83 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 EGO60436.1 - 0.38 10.3 4.1 0.99 9.0 1.1 2.2 1 1 0 2 2 2 0 RloB-like protein PB1 PF00564.19 EGO60436.1 - 0.45 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain SNARE PF05739.14 EGO60437.1 - 3.9e-19 68.0 1.9 3.9e-19 68.0 1.3 3.1 2 1 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EGO60437.1 - 5.1e-15 55.4 8.7 7.2e-15 55.0 0.9 2.4 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EGO60437.1 - 0.00065 19.2 9.1 0.12 11.8 1.4 2.8 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.1 EGO60437.1 - 0.034 14.1 8.6 0.15 12.1 2.3 2.5 2 1 0 2 2 2 0 Syntaxin-like protein DUF948 PF06103.6 EGO60437.1 - 0.24 11.2 5.7 6.3 6.7 0.2 3.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Med9 PF07544.8 EGO60437.1 - 0.52 10.0 5.1 10 5.9 0.1 3.4 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 H-kinase_dim PF02895.9 EGO60437.1 - 1.9 8.8 5.6 9.7 6.6 0.6 2.8 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DNA_repr_REX1B PF14966.1 EGO60437.1 - 2.3 8.6 6.7 0.19 12.1 0.2 2.6 3 1 0 3 3 3 0 DNA repair REX1-B IncA PF04156.9 EGO60437.1 - 4.3 6.8 16.1 6.5 6.3 0.6 3.3 3 0 0 3 3 3 0 IncA protein HAUS-augmin3 PF14932.1 EGO60437.1 - 5.7 6.0 10.5 0.9 8.6 1.3 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Herpes_capsid PF06112.6 EGO60437.1 - 7.6 6.5 7.4 6.7 6.7 2.6 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein AA_kinase PF00696.23 EGO60438.1 - 1.5e-39 135.9 0.4 2.5e-39 135.2 0.1 1.5 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.20 EGO60438.1 - 5.1e-14 51.3 1.5 8.3e-10 37.9 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 EGO60438.1 - 2.3e-13 49.4 3.1 5.1e-10 38.7 0.1 2.5 2 0 0 2 2 2 2 ACT domain ABC_membrane PF00664.18 EGO60439.1 - 1.2e-49 169.1 9.6 2.2e-49 168.3 6.6 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGO60439.1 - 4.6e-34 117.6 0.1 1.7e-33 115.8 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EGO60439.1 - 1.7e-05 24.1 0.1 0.00065 18.9 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGO60439.1 - 7.5e-05 22.7 0.4 0.00048 20.1 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 EGO60439.1 - 0.00023 21.2 1.0 0.81 9.5 0.1 2.6 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EGO60439.1 - 0.0025 18.6 0.1 0.0064 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGO60439.1 - 0.0042 17.2 0.1 0.023 14.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGO60439.1 - 0.0048 16.3 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 EGO60439.1 - 0.0053 16.9 0.2 0.055 13.6 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EGO60439.1 - 0.013 14.8 0.2 0.36 10.2 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.9 EGO60439.1 - 0.023 14.4 0.1 0.076 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 EGO60439.1 - 0.031 14.3 0.0 0.98 9.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain SbcCD_C PF13558.1 EGO60439.1 - 0.043 13.7 0.8 0.32 10.9 0.6 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EGO60439.1 - 0.058 12.7 0.7 0.43 9.9 0.5 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGO60439.1 - 0.085 13.1 0.1 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGO60439.1 - 0.094 12.1 0.5 0.49 9.7 0.2 2.1 2 0 0 2 2 2 0 AAA-like domain ABC_ATPase PF09818.4 EGO60439.1 - 0.1 11.1 0.9 0.16 10.4 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class CTD_bind PF04818.8 EGO60440.1 - 8e-22 77.2 0.1 1.9e-21 76.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. MSP1_C PF07462.6 EGO60440.1 - 0.013 13.9 0.0 0.022 13.1 0.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Clathrin_lg_ch PF01086.12 EGO60441.1 - 1.9e-76 256.9 2.3 2.1e-76 256.7 1.6 1.0 1 0 0 1 1 1 1 Clathrin light chain Peptidase_M3 PF01432.15 EGO60441.1 - 0.037 13.0 0.9 0.046 12.7 0.6 1.1 1 0 0 1 1 1 0 Peptidase family M3 rve_3 PF13683.1 EGO60441.1 - 0.12 11.9 0.5 0.26 10.8 0.4 1.6 1 0 0 1 1 1 0 Integrase core domain COX7a PF02238.10 EGO60442.1 - 0.0085 15.8 0.7 0.02 14.6 0.5 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIa Methyltransf_11 PF08241.7 EGO60445.1 - 0.0034 17.8 0.0 0.0071 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Metallophos PF00149.23 EGO60446.1 - 1.5e-14 53.8 0.1 2.9e-14 52.9 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGO60446.1 - 1.2e-05 25.1 0.0 2.8e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-CCHC PF00098.18 EGO60447.1 - 1.6e-11 43.5 9.7 1.9e-05 24.3 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EGO60447.1 - 7.9e-09 35.0 0.2 1.5e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EGO60447.1 - 1.1e-06 28.2 6.7 0.0004 20.0 2.7 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EGO60447.1 - 1.3e-05 24.6 0.2 3.1e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 EGO60447.1 - 0.00087 18.9 9.6 0.028 14.0 0.2 2.8 2 1 1 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.1 EGO60447.1 - 0.0012 18.4 6.0 0.3 10.7 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EGO60447.1 - 0.056 12.9 6.8 0.068 12.6 0.2 2.9 1 1 1 2 2 2 0 Zinc knuckle GST_N_3 PF13417.1 EGO60448.1 - 1.8e-15 56.9 0.0 3.9e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGO60448.1 - 2.5e-12 46.7 0.0 6.7e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGO60448.1 - 2.6e-12 46.5 0.0 5.2e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGO60448.1 - 6.9e-12 45.1 0.0 1.4e-11 44.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO60448.1 - 6.9e-12 45.0 0.1 1.2e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGO60448.1 - 1.8e-08 34.7 0.1 3.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAD_binding_4 PF01565.18 EGO60449.1 - 1.5e-17 63.3 1.8 1.5e-17 63.3 1.3 2.4 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.7 EGO60449.1 - 2e-13 49.9 3.5 2.3e-12 46.6 0.7 2.7 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 EGO60449.1 - 0.15 11.2 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding WTF PF03303.8 EGO60451.1 - 0.022 14.2 0.6 0.022 14.2 0.4 1.6 2 0 0 2 2 2 0 WTF protein PAT1 PF09770.4 EGO60452.1 - 0.0033 15.7 49.5 0.0037 15.5 34.3 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SRP-alpha_N PF04086.8 EGO60452.1 - 0.0066 15.8 17.8 0.0074 15.7 12.3 1.0 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Zip PF02535.17 EGO60452.1 - 0.008 15.2 2.7 0.0082 15.1 1.9 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Apt1 PF10351.4 EGO60452.1 - 0.013 14.3 10.8 0.014 14.2 7.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2828 PF11443.3 EGO60452.1 - 0.016 13.4 13.0 0.018 13.3 9.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Herpes_DNAp_acc PF04929.7 EGO60452.1 - 0.016 14.1 12.4 0.018 14.0 8.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor NARP1 PF12569.3 EGO60452.1 - 0.035 12.8 17.9 0.038 12.7 12.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pox_Ag35 PF03286.9 EGO60452.1 - 0.046 13.2 13.4 0.059 12.8 9.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4045 PF13254.1 EGO60452.1 - 0.066 12.5 18.7 0.076 12.2 12.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DDHD PF02862.12 EGO60452.1 - 0.068 12.9 18.1 0.083 12.6 12.6 1.1 1 0 0 1 1 1 0 DDHD domain Raftlin PF15250.1 EGO60452.1 - 0.079 11.4 18.2 0.091 11.2 12.6 1.0 1 0 0 1 1 1 0 Raftlin GPCR_chapero_1 PF11904.3 EGO60452.1 - 0.097 11.7 15.7 0.11 11.6 10.9 1.1 1 0 0 1 1 1 0 GPCR-chaperone Bul1_N PF04425.7 EGO60452.1 - 0.11 11.0 17.0 0.12 10.8 11.8 1.0 1 0 0 1 1 1 0 Bul1 N terminus SprA-related PF12118.3 EGO60452.1 - 0.11 11.8 51.5 0.14 11.4 35.7 1.1 1 0 0 1 1 1 0 SprA-related family AUX_IAA PF02309.11 EGO60452.1 - 0.11 12.1 17.9 0.14 11.8 12.4 1.1 1 0 0 1 1 1 0 AUX/IAA family RIC3 PF15361.1 EGO60452.1 - 0.13 12.4 21.1 0.17 12.0 14.6 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Herpes_env PF01673.13 EGO60452.1 - 0.15 10.5 16.0 0.19 10.2 11.1 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF1510 PF07423.6 EGO60452.1 - 0.16 11.3 24.7 0.18 11.1 17.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) eIF3_subunit PF08597.5 EGO60452.1 - 0.17 11.4 27.0 0.21 11.1 18.7 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit EcoRI_methylase PF13651.1 EGO60452.1 - 0.18 10.8 7.6 0.25 10.3 5.3 1.3 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI BTV_NS2 PF04514.7 EGO60452.1 - 0.19 10.6 14.6 0.2 10.4 10.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 AvrE PF11725.3 EGO60452.1 - 0.19 8.7 20.9 0.18 8.7 14.5 1.0 1 0 0 1 1 1 0 Pathogenicity factor FLO_LFY PF01698.11 EGO60452.1 - 0.23 10.2 18.3 0.26 10.0 12.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein CMV_1a PF12467.3 EGO60452.1 - 0.24 11.7 14.0 0.29 11.4 9.7 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Presenilin PF01080.12 EGO60452.1 - 0.27 10.0 12.9 0.31 9.8 9.0 1.1 1 0 0 1 1 1 0 Presenilin Mgr1 PF08602.5 EGO60452.1 - 0.28 10.1 9.5 0.32 9.9 6.6 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DHHW PF14286.1 EGO60452.1 - 0.28 10.4 17.1 0.33 10.2 11.8 1.0 1 0 0 1 1 1 0 DHHW protein SAGA-Tad1 PF12767.2 EGO60452.1 - 0.33 10.5 23.8 0.43 10.1 16.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Adeno_VII PF03228.9 EGO60452.1 - 0.33 11.5 9.1 0.43 11.1 6.3 1.3 1 0 0 1 1 1 0 Adenoviral core protein VII CDC45 PF02724.9 EGO60452.1 - 0.37 8.7 20.3 0.43 8.5 14.1 1.0 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 EGO60452.1 - 0.38 9.3 20.3 0.44 9.1 14.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.7 EGO60452.1 - 0.39 10.6 19.3 0.44 10.4 13.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Tyrosinase PF00264.15 EGO60452.1 - 0.4 10.7 11.3 0.44 10.6 7.8 1.1 1 0 0 1 1 1 0 Common central domain of tyrosinase Folate_carrier PF01770.13 EGO60452.1 - 0.45 8.9 13.4 0.69 8.3 9.3 1.4 1 0 0 1 1 1 0 Reduced folate carrier DUF4175 PF13779.1 EGO60452.1 - 0.46 8.1 68.6 0.62 7.7 47.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) LicD PF04991.8 EGO60452.1 - 0.46 10.5 4.4 0.55 10.3 3.1 1.1 1 0 0 1 1 1 0 LicD family PMSI1 PF15322.1 EGO60452.1 - 0.55 9.2 15.8 0.63 9.0 11.0 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative FNIP_N PF14636.1 EGO60452.1 - 0.63 10.5 23.6 0.86 10.0 16.3 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus DUF4465 PF14717.1 EGO60452.1 - 0.65 10.3 6.5 0.78 10.1 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4465) AAA_11 PF13086.1 EGO60452.1 - 0.67 9.4 22.5 0.8 9.2 15.6 1.1 1 0 0 1 1 1 0 AAA domain Rtf2 PF04641.7 EGO60452.1 - 0.71 9.0 22.5 0.87 8.7 15.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Calici_coat_C PF08435.6 EGO60452.1 - 0.71 9.1 13.8 0.84 8.8 9.5 1.1 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal Peptidase_C6 PF00851.13 EGO60452.1 - 0.73 8.4 14.8 0.8 8.2 10.2 1.0 1 0 0 1 1 1 0 Helper component proteinase AAA_13 PF13166.1 EGO60452.1 - 0.74 8.2 20.0 0.82 8.0 13.9 1.0 1 0 0 1 1 1 0 AAA domain Plasmodium_Vir PF05795.6 EGO60452.1 - 0.76 8.9 9.5 0.89 8.6 6.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein VID27 PF08553.5 EGO60452.1 - 0.84 7.7 14.5 0.9 7.6 10.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Tim54 PF11711.3 EGO60452.1 - 0.86 8.1 15.2 1 7.8 10.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TT_ORF1 PF02956.9 EGO60452.1 - 0.87 7.9 18.4 0.94 7.8 12.7 1.0 1 0 0 1 1 1 0 TT viral orf 1 Spore_coat_CotO PF14153.1 EGO60452.1 - 0.89 8.9 33.4 1.1 8.6 23.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO FAM60A PF15396.1 EGO60452.1 - 0.94 9.1 19.1 1.3 8.7 13.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Peptidase_U57 PF05582.7 EGO60452.1 - 0.97 8.3 15.9 1.3 7.9 11.0 1.3 1 0 0 1 1 1 0 YabG peptidase U57 DUF966 PF06136.8 EGO60452.1 - 1.1 8.6 22.2 1.2 8.4 15.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SpoVR PF04293.8 EGO60452.1 - 1.1 7.5 19.8 1.2 7.3 13.7 1.1 1 0 0 1 1 1 0 SpoVR like protein DUF605 PF04652.11 EGO60452.1 - 1.2 8.5 31.1 1.3 8.2 21.6 1.1 1 0 0 1 1 1 0 Vta1 like Kei1 PF08552.6 EGO60452.1 - 1.3 8.6 14.3 1.9 8.1 9.9 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 TFIIA PF03153.8 EGO60452.1 - 1.3 8.8 43.7 1.5 8.6 30.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Band_3_cyto PF07565.8 EGO60452.1 - 1.5 8.2 22.2 2.1 7.7 15.4 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S15 PF02129.13 EGO60452.1 - 1.7 8.0 18.8 2.1 7.6 13.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Ycf1 PF05758.7 EGO60452.1 - 1.7 6.2 24.7 1.9 6.0 17.1 1.0 1 0 0 1 1 1 0 Ycf1 Cellulose_synt PF03552.9 EGO60452.1 - 2 6.6 10.5 2.2 6.4 7.3 1.1 1 0 0 1 1 1 0 Cellulose synthase CobT PF06213.7 EGO60452.1 - 2 7.4 18.8 2.3 7.2 13.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BORG_CEP PF14957.1 EGO60452.1 - 2 9.3 14.6 2.9 8.8 10.1 1.3 1 0 0 1 1 1 0 Cdc42 effector DUF2126 PF09899.4 EGO60452.1 - 2.1 6.2 16.3 2.4 6.0 11.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) FAM220 PF15487.1 EGO60452.1 - 2.1 7.6 16.6 2.5 7.4 11.5 1.0 1 0 0 1 1 1 0 FAM220 family Senescence_reg PF04520.8 EGO60452.1 - 2.4 8.6 14.1 3.1 8.2 9.8 1.3 1 0 0 1 1 1 0 Senescence regulator Gti1_Pac2 PF09729.4 EGO60452.1 - 2.5 7.9 18.6 3.5 7.4 12.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Hid1 PF12722.2 EGO60452.1 - 2.6 5.6 26.3 3 5.4 18.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raffinose_syn PF05691.7 EGO60452.1 - 2.8 5.3 8.1 3 5.2 5.6 1.0 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Adeno_hexon PF01065.14 EGO60452.1 - 2.9 6.6 16.0 3.4 6.4 11.1 1.0 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain RR_TM4-6 PF06459.7 EGO60452.1 - 2.9 7.7 24.8 4 7.2 17.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paramyxo_ncap PF00973.14 EGO60452.1 - 2.9 6.4 19.9 3.4 6.2 13.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein eIF-3_zeta PF05091.7 EGO60452.1 - 2.9 6.3 31.9 3.5 6.1 22.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Calsarcin PF05556.6 EGO60452.1 - 3 6.9 21.5 4 6.5 14.9 1.1 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) Peptidase_S64 PF08192.6 EGO60452.1 - 3.1 6.0 19.7 3.7 5.7 13.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 Mem_trans PF03547.13 EGO60452.1 - 3.1 5.9 12.5 3.7 5.7 8.7 1.1 1 0 0 1 1 1 0 Membrane transport protein PIH1 PF08190.7 EGO60452.1 - 3.1 7.1 29.6 3.8 6.8 20.5 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 CPSF100_C PF13299.1 EGO60452.1 - 3.1 7.9 21.5 4.1 7.5 14.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal UPF0560 PF10577.4 EGO60452.1 - 3.2 5.9 32.8 4.3 5.4 22.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Dehalogenase PF13486.1 EGO60452.1 - 3.3 7.0 14.3 4 6.7 9.9 1.1 1 0 0 1 1 1 0 Reductive dehalogenase subunit Med15 PF09606.5 EGO60452.1 - 3.3 5.7 77.2 3.8 5.5 53.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FYDLN_acid PF09538.5 EGO60452.1 - 3.4 8.3 13.5 5.1 7.7 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) HGTP_anticodon2 PF12745.2 EGO60452.1 - 3.8 6.5 20.1 5 6.1 13.9 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Baculo_PP31 PF05311.6 EGO60452.1 - 4 6.6 24.0 5.2 6.2 16.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Pal1 PF08316.6 EGO60452.1 - 4.2 7.8 13.0 6.6 7.1 9.0 1.4 1 0 0 1 1 1 0 Pal1 cell morphology protein DDRGK PF09756.4 EGO60452.1 - 4.2 6.7 35.5 5.1 6.4 24.6 1.1 1 0 0 1 1 1 0 DDRGK domain PCEMA1 PF07418.6 EGO60452.1 - 4.3 6.6 11.7 4.8 6.4 8.1 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 DUF4613 PF15390.1 EGO60452.1 - 4.6 5.2 17.9 5.2 5.1 12.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) 2OG-FeII_Oxy_2 PF13532.1 EGO60452.1 - 4.6 7.0 18.9 5.6 6.7 13.1 1.1 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PPP4R2 PF09184.6 EGO60452.1 - 4.9 6.6 20.8 6.2 6.2 14.4 1.1 1 0 0 1 1 1 0 PPP4R2 YABBY PF04690.8 EGO60452.1 - 5.7 7.1 16.1 8.7 6.5 11.2 1.4 1 0 0 1 1 1 0 YABBY protein DUF940 PF06082.6 EGO60452.1 - 6.8 5.1 17.8 7.7 4.9 12.4 1.0 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Neur_chan_memb PF02932.11 EGO60452.1 - 6.8 6.5 19.1 8.2 6.2 13.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Gag_spuma PF03276.9 EGO60452.1 - 7.1 4.8 45.0 8.4 4.5 31.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Serinc PF03348.10 EGO60452.1 - 7.4 5.1 21.3 11 4.6 14.8 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) AMP-binding PF00501.23 EGO60452.1 - 7.4 4.8 6.1 8.5 4.6 4.2 1.1 1 0 0 1 1 1 0 AMP-binding enzyme SPX PF03105.14 EGO60452.1 - 7.7 6.2 23.4 9 5.9 16.2 1.1 1 0 0 1 1 1 0 SPX domain CKAP2_C PF15297.1 EGO60452.1 - 7.9 5.1 26.1 10 4.8 18.1 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF913 PF06025.7 EGO60452.1 - 8.2 5.0 14.9 11 4.6 10.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoIIP PF07454.6 EGO60452.1 - 8.2 5.5 19.8 10 5.1 13.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2058 PF09831.4 EGO60452.1 - 8.2 6.2 43.3 10 5.9 30.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF2201_N PF13203.1 EGO60452.1 - 8.3 5.4 26.8 13 4.8 18.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain FHIPEP PF00771.15 EGO60452.1 - 9.1 4.4 18.6 13 3.9 12.9 1.2 1 0 0 1 1 1 0 FHIPEP family FAM222A PF15258.1 EGO60452.1 - 9.3 5.3 33.3 10 5.1 23.1 1.1 1 0 0 1 1 1 0 Protein family of FAM222A hDGE_amylase PF14701.1 EGO60452.1 - 9.6 4.9 15.6 12 4.7 10.8 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme RP-C_C PF11800.3 EGO60452.1 - 10 5.7 20.8 12 5.4 14.4 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF3384 PF11864.3 EGO60453.1 - 3.6e-112 375.1 0.0 4.8e-112 374.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EGO60453.1 - 5.4e-53 179.1 0.0 9.7e-53 178.3 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EGO60453.1 - 7.5e-33 114.0 0.5 1.5e-29 103.1 0.0 2.3 2 0 0 2 2 2 2 Tuberin Nup188 PF10487.4 EGO60453.1 - 0.051 11.4 0.0 0.08 10.8 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 CAS_CSE1 PF03378.10 EGO60455.1 - 2.9e-177 589.3 0.0 9.3e-177 587.6 0.0 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EGO60455.1 - 2.5e-152 506.7 0.5 4.4e-152 505.9 0.3 1.4 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 EGO60455.1 - 1e-12 47.7 0.0 3e-12 46.2 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EGO60455.1 - 0.014 15.3 3.6 0.35 10.7 0.0 4.6 5 2 0 5 5 5 0 Exportin 1-like protein Aconitase_B_N PF11791.3 EGO60455.1 - 0.063 13.1 0.0 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 Aconitate B N-terminal domain HEAT_2 PF13646.1 EGO60455.1 - 0.073 13.3 2.3 6.5 7.1 0.0 3.7 3 1 1 4 4 4 0 HEAT repeats Alliinase_C PF04864.8 EGO60457.1 - 0.08 11.5 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Allinase WD40 PF00400.27 EGO60458.1 - 2.2e-19 68.5 6.9 1.5e-06 27.8 0.1 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat CLTH PF10607.4 EGO60458.1 - 0.00029 20.5 0.0 0.00075 19.2 0.0 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Dynamin_M PF01031.15 EGO60459.1 - 3.1e-107 357.7 1.0 7.1e-107 356.5 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EGO60459.1 - 2.8e-57 193.1 0.0 6e-57 192.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EGO60459.1 - 2.6e-29 100.9 9.9 6.6e-29 99.6 5.3 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGO60459.1 - 5.7e-05 23.0 1.2 0.0006 19.7 0.2 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EGO60459.1 - 0.012 16.1 0.0 0.041 14.3 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein CoA_transf_3 PF02515.12 EGO60460.1 - 6.2e-50 169.1 0.0 8e-50 168.7 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Glutaredoxin PF00462.19 EGO60462.1 - 1.4e-15 57.0 0.0 2.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin ABC_tran PF00005.22 EGO60463.1 - 1.7e-14 54.2 0.0 1.4e-13 51.2 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGO60463.1 - 8e-10 39.1 0.1 0.00044 20.3 0.3 2.1 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGO60463.1 - 0.00035 20.0 0.1 0.00067 19.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 EGO60463.1 - 0.00054 17.4 0.2 0.00073 17.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_15 PF13175.1 EGO60463.1 - 0.0019 17.3 0.0 0.12 11.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 EGO60463.1 - 0.003 17.0 0.0 0.0044 16.5 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.14 EGO60463.1 - 0.003 16.8 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGO60463.1 - 0.0049 16.8 0.2 0.014 15.3 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EGO60463.1 - 0.0051 16.2 0.4 0.013 14.8 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EGO60463.1 - 0.0055 16.8 0.0 0.027 14.6 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGO60463.1 - 0.0079 17.0 0.4 0.019 15.7 0.3 2.0 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EGO60463.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EGO60463.1 - 0.012 15.9 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGO60463.1 - 0.012 15.5 0.5 0.024 14.5 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGO60463.1 - 0.012 15.4 0.0 0.052 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGO60463.1 - 0.016 15.3 0.1 0.059 13.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGO60463.1 - 0.023 13.8 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arf PF00025.16 EGO60463.1 - 0.041 13.1 0.2 0.097 11.9 0.2 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family SRP54 PF00448.17 EGO60463.1 - 0.041 13.3 0.1 0.064 12.7 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.1 EGO60463.1 - 0.12 10.8 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGO60463.1 - 0.13 11.9 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 EGO60463.1 - 0.2 11.0 0.2 0.31 10.4 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Pkinase PF00069.20 EGO60464.1 - 1.2e-68 231.0 0.0 3.3e-68 229.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO60464.1 - 2.2e-48 164.5 0.0 3.7e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO60464.1 - 1.4e-05 24.2 0.0 8.3e-05 21.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like ACT_3 PF10000.4 EGO60464.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 ACT domain Transglut_core PF01841.14 EGO60465.1 - 1.9e-12 47.3 0.5 4.5e-12 46.1 0.1 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.12 EGO60465.1 - 7e-08 31.8 0.2 1.5e-07 30.7 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO60465.1 - 0.00021 20.6 0.2 0.00021 20.6 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EGO60465.1 - 0.0003 20.3 0.2 0.00066 19.2 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain RskA PF10099.4 EGO60466.1 - 0.054 13.2 0.9 0.072 12.8 0.6 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Transthyretin PF00576.16 EGO60467.1 - 4.1e-27 94.2 0.2 2e-24 85.6 0.1 2.0 1 1 0 1 1 1 1 HIUase/Transthyretin family Aminotran_5 PF00266.14 EGO60468.1 - 3.6e-29 101.6 0.0 2.8e-20 72.3 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V DUF2264 PF10022.4 EGO60469.1 - 1.8e-123 411.7 0.1 2.2e-123 411.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Surf_Ag_VNR PF07244.10 EGO60469.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat FH2 PF02181.18 EGO60470.1 - 1e-83 281.2 4.5 2.3e-83 280.1 3.1 1.6 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EGO60470.1 - 1.5e-67 226.6 0.1 5.6e-67 224.7 0.0 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EGO60470.1 - 2.7e-54 183.5 3.7 9.8e-54 181.7 1.5 2.7 1 1 1 2 2 2 1 Diaphanous FH3 Domain DUF131 PF01998.12 EGO60471.1 - 0.47 9.8 4.0 0.8 9.1 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF131 Pkinase PF00069.20 EGO60473.1 - 6e-64 215.6 0.0 7.1e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO60473.1 - 1.1e-30 106.5 0.0 1.4e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO60473.1 - 0.0069 15.3 0.0 0.016 14.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like MadM PF03818.8 EGO60474.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit CMAS PF02353.15 EGO60475.1 - 1.3e-37 129.3 0.2 1.9e-37 128.8 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EGO60475.1 - 5.2e-16 58.5 0.0 9.7e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO60475.1 - 1.5e-15 57.4 0.0 3.6e-15 56.2 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO60475.1 - 6.2e-14 52.0 0.0 9.7e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO60475.1 - 3.5e-10 40.2 0.0 8.3e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO60475.1 - 3.6e-10 40.4 0.0 7.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO60475.1 - 2.6e-08 33.2 0.0 4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGO60475.1 - 1.4e-05 25.3 0.0 2.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO60475.1 - 1.5e-05 24.1 0.0 3.7e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EGO60475.1 - 2.9e-05 23.4 0.0 5.9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 EGO60475.1 - 0.00012 21.5 0.0 0.00021 20.6 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.14 EGO60475.1 - 0.0033 16.9 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 EGO60475.1 - 0.007 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 EGO60475.1 - 0.03 14.3 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain P5-ATPase PF12409.3 EGO60476.1 - 1.6e-38 131.2 0.5 3.9e-37 126.7 0.0 2.4 2 0 0 2 2 2 1 P5-type ATPase cation transporter HAD PF12710.2 EGO60476.1 - 1.5e-29 103.5 0.0 2.8e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGO60476.1 - 2.4e-23 82.3 0.0 4.8e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGO60476.1 - 2.1e-14 54.4 0.0 6.2e-13 49.6 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EGO60476.1 - 0.00013 21.5 6.5 0.00013 21.5 4.5 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 EGO60476.1 - 0.0044 16.4 0.0 0.0093 15.4 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EGO60476.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGO60476.1 - 0.068 12.7 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NAP PF00956.13 EGO60477.1 - 1.8e-88 295.8 14.2 1.8e-88 295.8 9.8 2.1 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) 2-Hacid_dh_C PF02826.14 EGO60478.1 - 2.7e-54 183.0 0.0 4.5e-54 182.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGO60478.1 - 4.2e-38 129.8 0.1 5.6e-38 129.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGO60478.1 - 5e-07 29.7 0.2 1.4e-06 28.2 0.2 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EGO60478.1 - 7.9e-05 22.5 0.1 0.0002 21.2 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 EGO60478.1 - 0.00024 20.5 0.1 0.033 13.5 0.0 2.6 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain ACT PF01842.20 EGO60478.1 - 0.0024 17.3 0.1 0.0086 15.5 0.1 2.0 1 0 0 1 1 1 1 ACT domain XdhC_C PF13478.1 EGO60478.1 - 0.077 13.3 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.13 EGO60478.1 - 0.38 10.3 3.4 3.1 7.4 0.6 2.8 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Myosin_head PF00063.16 EGO60479.1 - 7.9e-241 800.8 0.0 7.9e-241 800.8 0.0 1.5 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EGO60479.1 - 9.2e-35 118.7 3.5 2.5e-34 117.2 2.4 1.8 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EGO60479.1 - 3.2e-14 51.1 29.4 2e-06 26.9 0.3 7.1 7 0 0 7 7 7 5 IQ calmodulin-binding motif GAS PF13851.1 EGO60479.1 - 3.1e-05 23.2 24.5 0.00033 19.9 17.1 2.4 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding ERM PF00769.14 EGO60479.1 - 6.1e-05 22.6 20.1 0.00017 21.2 13.9 1.7 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Myosin_N PF02736.14 EGO60479.1 - 0.00036 20.1 3.2 0.00079 19.0 2.2 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 EGO60479.1 - 0.0029 17.7 0.0 0.013 15.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain FlaC_arch PF05377.6 EGO60479.1 - 0.007 16.2 0.1 0.007 16.2 0.1 3.7 2 1 0 3 3 3 1 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 EGO60479.1 - 0.01 15.0 2.0 0.027 13.6 1.3 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein AAA_19 PF13245.1 EGO60479.1 - 0.035 13.8 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain FUSC PF04632.7 EGO60479.1 - 1.5 7.1 9.8 2.8 6.2 6.8 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family EMP24_GP25L PF01105.19 EGO60479.1 - 3.4 7.3 11.9 1.4 8.5 2.4 3.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD APG6 PF04111.7 EGO60479.1 - 4.3 6.3 28.6 3.2 6.7 14.6 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 AAA_18 PF13238.1 EGO60480.1 - 2.1e-28 99.2 3.5 2.6e-28 98.8 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EGO60480.1 - 7.7e-16 59.0 2.0 1.2e-15 58.3 0.3 1.8 1 1 1 2 2 2 1 AAA domain ADK PF00406.17 EGO60480.1 - 4.5e-06 26.6 0.1 0.0052 16.6 0.0 2.2 1 1 0 2 2 2 2 Adenylate kinase AAA PF00004.24 EGO60480.1 - 5.9e-05 23.2 0.0 0.0009 19.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 EGO60480.1 - 0.00031 20.6 0.4 0.0012 18.7 0.3 1.8 1 1 0 1 1 1 1 Shikimate kinase AAA_28 PF13521.1 EGO60480.1 - 0.00041 20.3 0.0 0.00083 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO60480.1 - 0.00078 19.3 0.1 0.0088 15.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EGO60480.1 - 0.002 17.5 0.3 1.1 8.6 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase NTPase_1 PF03266.10 EGO60480.1 - 0.0069 16.1 0.1 0.019 14.7 0.0 1.8 2 0 0 2 2 2 1 NTPase AAA_16 PF13191.1 EGO60480.1 - 0.0095 15.9 0.1 0.036 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain KTI12 PF08433.5 EGO60480.1 - 0.012 14.8 0.3 0.069 12.3 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_22 PF13401.1 EGO60480.1 - 0.02 15.0 0.1 0.027 14.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGO60480.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.1 EGO60480.1 - 0.025 14.5 0.1 0.087 12.7 0.0 2.1 1 1 1 2 2 2 0 Cytidylate kinase-like family DUF3221 PF11518.3 EGO60480.1 - 0.044 13.4 0.8 0.092 12.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) RNA_helicase PF00910.17 EGO60480.1 - 0.096 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 EGO60480.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Ham1p_like PF01725.11 EGO60481.1 - 2.8e-51 173.5 0.0 3.3e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_C78 PF07910.8 EGO60482.1 - 7.7e-70 234.4 0.0 1.1e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C39_2 PF13529.1 EGO60482.1 - 0.097 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase_C39 like family Zn_clus PF00172.13 EGO60483.1 - 7.1e-09 35.4 9.8 1.1e-08 34.8 6.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 EGO60483.1 - 3.9 6.2 6.3 6 5.5 4.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF605 PF04652.11 EGO60483.1 - 5.6 6.2 14.5 8 5.7 10.0 1.3 1 0 0 1 1 1 0 Vta1 like tRNA-synt_2b PF00587.20 EGO60484.1 - 9.1e-36 123.0 0.0 1.5e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EGO60484.1 - 2.5e-13 49.9 5.6 5.9e-13 48.7 3.9 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain AAA_27 PF13514.1 EGO60484.1 - 0.027 12.1 1.0 0.039 11.6 0.7 1.1 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 EGO60485.1 - 4.5e-46 156.2 0.0 5.1e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO60485.1 - 6e-15 55.7 0.1 7.9e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO60485.1 - 7.1e-07 28.6 0.0 8.4e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGO60485.1 - 1e-06 28.7 0.0 1.4e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO60485.1 - 1.3e-05 24.6 0.0 0.00014 21.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGO60485.1 - 0.0001 21.6 0.0 0.00022 20.4 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EGO60485.1 - 0.022 14.0 0.0 0.11 11.7 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.1 EGO60485.1 - 0.028 14.2 0.0 0.049 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain WAPL PF07814.8 EGO60486.1 - 6e-17 61.3 1.7 5.6e-16 58.2 1.1 2.3 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.1 EGO60487.1 - 4.4e-79 264.4 0.0 5.7e-79 264.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EGO60487.1 - 7.3e-05 22.4 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EGO60487.1 - 0.14 11.8 0.2 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) GTP_CH_N PF12471.3 EGO60489.1 - 1.5e-91 305.3 0.0 2.1e-91 304.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EGO60489.1 - 1.5e-15 56.8 0.0 2.3e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Picorna_P3A PF06363.6 EGO60490.1 - 0.11 12.4 0.3 0.27 11.2 0.2 1.6 1 1 0 1 1 1 0 Picornaviridae P3A protein Ribosomal_S3Ae PF01015.13 EGO60492.1 - 5.2e-82 273.9 3.9 6.2e-82 273.6 2.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Ras PF00071.17 EGO60493.1 - 1.3e-48 164.4 0.0 1.6e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO60493.1 - 2.9e-16 60.0 0.0 4.2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO60493.1 - 5.5e-12 45.2 0.0 7.2e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGO60493.1 - 3.1e-05 23.9 0.0 0.00024 21.0 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO60493.1 - 0.00018 20.9 0.0 0.00065 19.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGO60493.1 - 0.0015 17.7 0.0 0.0018 17.4 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 EGO60493.1 - 0.0044 16.9 0.0 0.0099 15.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO60493.1 - 0.0051 16.8 0.0 0.01 15.8 0.0 1.7 1 1 1 2 2 2 1 AAA ATPase domain SRPRB PF09439.5 EGO60493.1 - 0.0071 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EGO60493.1 - 0.0075 16.4 0.0 0.017 15.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGO60493.1 - 0.01 15.3 0.1 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EGO60493.1 - 0.023 13.9 0.0 0.055 12.6 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EGO60493.1 - 0.027 13.9 0.0 0.056 12.8 0.0 1.5 1 1 1 2 2 2 0 AAA-like domain ABC_tran PF00005.22 EGO60493.1 - 0.045 14.0 0.1 0.1 12.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EGO60493.1 - 0.05 13.3 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EGO60493.1 - 0.13 13.0 0.1 0.19 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.2 EGO60494.1 - 2.7e-30 105.9 0.1 3.9e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO60494.1 - 1.1e-20 74.2 0.1 2.9e-19 69.5 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO60494.1 - 8.4e-11 41.8 0.0 1.6e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EGO60494.1 - 4e-08 33.1 0.1 1.2e-07 31.5 0.1 1.7 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 EGO60494.1 - 3.9e-05 23.2 0.0 5.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 EGO60494.1 - 0.00059 20.1 0.0 0.00079 19.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Acyl_transf_1 PF00698.16 EGO60494.1 - 0.0025 17.1 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain DUF915 PF06028.6 EGO60494.1 - 0.058 12.4 0.0 2.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) UPF0227 PF05728.7 EGO60494.1 - 0.092 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) SRP72 PF08492.7 EGO60495.1 - 1.6e-18 66.7 10.9 1.6e-18 66.7 7.6 2.0 2 0 0 2 2 1 1 SRP72 RNA-binding domain TPR_2 PF07719.12 EGO60495.1 - 5.2e-07 29.0 24.1 0.11 12.4 0.2 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGO60495.1 - 3.7e-06 27.4 35.1 0.002 18.7 1.8 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO60495.1 - 0.00016 21.9 32.1 0.89 9.9 0.1 6.9 4 3 2 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EGO60495.1 - 0.00019 21.3 24.7 0.087 12.7 0.1 7.0 4 3 3 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 EGO60495.1 - 0.00021 21.3 13.6 0.0021 18.1 2.7 4.8 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 EGO60495.1 - 0.0059 16.5 0.2 7.6 6.7 0.1 4.8 6 0 0 6 6 6 1 PPR repeat TPR_7 PF13176.1 EGO60495.1 - 0.034 13.9 16.8 3 7.8 0.0 6.4 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGO60495.1 - 0.11 13.2 38.1 0.99 10.2 0.2 9.7 7 3 3 10 10 10 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGO60495.1 - 0.16 11.6 21.7 1.2 8.8 0.7 6.0 5 1 1 6 6 6 0 TPR repeat TPR_4 PF07721.9 EGO60495.1 - 0.26 11.8 19.2 4.2 8.0 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_5 PF12688.2 EGO60495.1 - 0.97 9.4 12.3 0.13 12.2 0.3 4.0 3 1 1 4 4 4 0 Tetratrico peptide repeat TPT PF03151.11 EGO60496.1 - 1.1e-29 103.0 14.3 1.1e-29 103.0 9.9 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EGO60496.1 - 5.4e-05 22.2 21.7 0.00016 20.7 15.1 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGO60496.1 - 0.0033 17.4 37.3 0.025 14.6 8.6 2.7 3 0 0 3 3 3 2 EamA-like transporter family dsDNA_bind PF01984.15 EGO60497.1 - 0.0066 16.4 9.7 0.015 15.3 6.7 1.6 1 1 0 1 1 1 1 Double-stranded DNA-binding domain RAB3GAP2_N PF14655.1 EGO60497.1 - 0.4 9.6 5.3 0.51 9.2 3.6 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4175 PF13779.1 EGO60497.1 - 3 5.4 11.1 3.2 5.3 7.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) BAF1_ABF1 PF04684.8 EGO60497.1 - 4.3 6.0 11.0 4.7 5.9 7.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor UCH PF00443.24 EGO60498.1 - 8.2e-37 126.7 0.0 1.1e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO60498.1 - 9.8e-06 25.2 0.0 3.1e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2387 PF09526.5 EGO60498.1 - 0.12 12.3 2.1 1.9 8.4 0.0 3.0 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) Alb1 PF09135.6 EGO60499.1 - 6.7e-29 100.7 12.5 6.7e-29 100.7 8.6 1.8 2 0 0 2 2 2 1 Alb1 DUF2239 PF09998.4 EGO60499.1 - 0.037 13.6 0.5 0.037 13.6 0.4 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) DUF1754 PF08555.5 EGO60499.1 - 0.67 10.5 11.5 6.7 7.3 0.4 2.4 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) PcfJ PF14284.1 EGO60499.1 - 0.72 9.3 5.2 0.13 11.7 0.6 1.8 2 0 0 2 2 2 0 PcfJ-like protein bZIP_2 PF07716.10 EGO60500.1 - 8.4e-10 38.3 4.5 1.9e-09 37.1 3.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EGO60500.1 - 8.7e-10 38.4 5.9 1.8e-09 37.3 4.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EGO60500.1 - 0.022 15.0 4.3 0.049 13.9 2.9 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor Rep_fac-A_3 PF08661.6 EGO60503.1 - 2.3e-26 91.8 0.0 2.5e-26 91.6 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF4431 PF14485.1 EGO60503.1 - 1.1 8.8 3.2 0.56 9.8 0.4 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4431) GATA PF00320.22 EGO60504.1 - 0.0012 18.0 6.3 0.059 12.7 1.6 2.5 2 0 0 2 2 2 2 GATA zinc finger Peptidase_M14 PF00246.19 EGO60507.1 - 6.1e-69 232.7 0.0 7.6e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.15 EGO60508.1 - 4.8e-39 133.9 0.1 8.2e-39 133.2 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EGO60508.1 - 4.3e-06 26.8 0.0 1.2e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EGO60508.1 - 7.7e-05 22.8 0.0 0.00016 21.8 0.0 1.6 1 0 0 1 1 1 1 PH domain COMPASS-Shg1 PF05205.7 EGO60509.1 - 5.7e-25 87.6 0.6 5.7e-25 87.6 0.4 1.9 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 CR6_interact PF10147.4 EGO60510.1 - 0.015 14.6 0.1 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF998 PF06197.8 EGO60510.1 - 0.026 13.8 0.4 0.029 13.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) IF-2B PF01008.12 EGO60511.1 - 1.2e-48 165.6 0.0 3e-48 164.2 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family IF3_C PF00707.17 EGO60512.1 - 8.2e-12 44.7 2.4 1.4e-11 43.9 1.6 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EGO60512.1 - 9.1e-05 21.9 3.0 0.00016 21.1 2.1 1.3 1 0 0 1 1 1 1 Mitochondrial translation initiation factor DUF3723 PF12520.3 EGO60512.1 - 0.061 11.7 1.3 0.091 11.2 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) Arm PF00514.18 EGO60513.1 - 9.6e-70 228.2 30.2 2.7e-13 49.1 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGO60513.1 - 1.5e-22 79.6 16.1 9.6e-07 29.0 0.3 7.8 2 2 3 6 6 6 5 HEAT repeats HEAT PF02985.17 EGO60513.1 - 8.8e-19 65.8 15.0 0.032 14.3 0.1 9.5 11 0 0 11 11 10 5 HEAT repeat HEAT_EZ PF13513.1 EGO60513.1 - 2e-15 56.7 17.2 0.00055 20.3 0.3 8.7 8 2 2 10 10 9 5 HEAT-like repeat Adaptin_N PF01602.15 EGO60513.1 - 1.3e-10 40.2 10.2 2.9e-09 35.7 2.2 3.2 2 1 0 4 4 4 2 Adaptin N terminal region KAP PF05804.7 EGO60513.1 - 7.1e-09 34.1 0.8 1.4e-08 33.2 0.6 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EGO60513.1 - 2.1e-08 33.6 2.2 0.029 13.5 0.1 4.1 2 1 1 3 3 3 2 V-ATPase subunit H Arm_2 PF04826.8 EGO60513.1 - 4.7e-07 29.1 8.0 0.0028 16.8 0.5 4.2 2 2 2 4 4 4 2 Armadillo-like DUF2454 PF10521.4 EGO60513.1 - 0.0032 16.4 0.1 0.0068 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) DUF908 PF06012.7 EGO60513.1 - 0.0044 16.3 5.4 0.96 8.6 0.1 4.3 3 1 2 5 5 5 1 Domain of Unknown Function (DUF908) PUL PF08324.6 EGO60513.1 - 0.012 14.3 2.3 0.04 12.7 0.4 2.6 2 0 0 2 2 2 0 PUL domain HEAT_PBS PF03130.11 EGO60513.1 - 0.028 14.8 8.1 74 4.2 0.1 7.0 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat Vpu PF00558.14 EGO60513.1 - 0.1 12.1 0.5 0.33 10.5 0.1 2.0 2 0 0 2 2 2 0 Vpu protein CBS PF00571.23 EGO60514.1 - 2.7e-32 110.2 7.8 1e-13 50.8 0.1 4.3 4 0 0 4 4 4 4 CBS domain RhoGAP PF00620.22 EGO60515.1 - 6.2e-11 42.1 0.0 1.3e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain CAF-1_p150 PF11600.3 EGO60516.1 - 3e-07 30.0 21.8 3e-07 30.0 15.1 3.4 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal PGAP1 PF07819.8 EGO60516.1 - 1.2e-06 28.2 0.0 8.9e-06 25.4 0.0 2.2 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EGO60516.1 - 1.6e-05 24.3 0.0 3.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EGO60516.1 - 2.9e-05 23.8 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO60516.1 - 0.00021 21.2 0.8 0.0007 19.5 0.6 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 EGO60516.1 - 0.00047 19.9 0.1 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.15 EGO60516.1 - 0.024 14.1 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 EGO60516.1 - 0.038 14.1 0.0 0.038 14.1 0.0 2.9 3 0 0 3 3 3 0 Thioesterase domain Lipase_3 PF01764.20 EGO60516.1 - 0.12 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Adeno_E3_CR2 PF02439.10 EGO60517.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CDK5_activator PF03261.10 EGO60517.1 - 2.1 7.5 5.0 3.6 6.8 3.5 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Fungal_trans PF04082.13 EGO60518.1 - 4.2e-30 104.4 0.0 8.2e-30 103.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO60518.1 - 1.1e-10 41.2 11.3 1.8e-10 40.5 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 EGO60518.1 - 0.0032 16.9 9.7 0.0084 15.5 0.1 2.2 2 0 0 2 2 2 2 Vta1 like Peptidase_M41 PF01434.13 EGO60519.1 - 4.5e-76 255.0 0.0 6.7e-76 254.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EGO60519.1 - 1.6e-43 148.0 0.1 9.4e-43 145.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EGO60519.1 - 2.1e-08 34.3 0.2 1.2e-07 31.8 0.0 2.4 2 1 0 2 2 2 1 FtsH Extracellular AAA_22 PF13401.1 EGO60519.1 - 0.0012 18.9 0.1 0.1 12.7 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGO60519.1 - 0.0026 17.4 0.0 0.01 15.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EGO60519.1 - 0.0092 15.4 0.1 0.03 13.7 0.1 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EGO60519.1 - 0.011 14.5 0.0 0.018 13.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 EGO60519.1 - 0.012 14.9 2.0 0.1 12.0 0.1 2.9 2 1 1 3 3 3 0 AAA domain RuvB_N PF05496.7 EGO60519.1 - 0.013 14.5 0.0 0.033 13.2 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGO60519.1 - 0.013 15.4 0.8 0.2 11.6 0.1 2.9 2 1 1 3 3 3 0 AAA ATPase domain AAA_19 PF13245.1 EGO60519.1 - 0.015 15.0 1.9 0.019 14.6 0.4 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_14 PF13173.1 EGO60519.1 - 0.017 15.0 0.0 0.06 13.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGO60519.1 - 0.018 15.8 0.0 0.14 12.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.9 EGO60519.1 - 0.022 14.6 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) HCO3_cotransp PF00955.16 EGO60520.1 - 8.2e-72 242.4 9.6 2.1e-42 145.4 1.9 2.1 1 1 1 2 2 2 2 HCO3- transporter family Homeobox PF00046.24 EGO60522.1 - 1.7e-08 33.9 3.1 4.4e-08 32.6 2.2 1.7 1 0 0 1 1 1 1 Homeobox domain 3HCDH_N PF02737.13 EGO60525.1 - 1.6e-51 174.5 0.2 2.1e-51 174.1 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EGO60525.1 - 7.7e-33 112.7 0.0 1.5e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Saccharop_dh PF03435.13 EGO60525.1 - 0.0017 17.4 0.1 0.0026 16.8 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 EGO60525.1 - 0.0064 16.3 0.0 0.014 15.2 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EGO60525.1 - 0.023 14.4 0.1 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 EGO60525.1 - 0.029 13.2 0.0 0.045 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO60525.1 - 0.034 14.1 0.8 0.19 11.7 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 EGO60525.1 - 0.041 14.3 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.22 EGO60525.1 - 0.056 13.8 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TIMELESS PF04821.9 EGO60526.1 - 3.2e-93 311.8 0.0 3.2e-93 311.8 0.0 2.9 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.8 EGO60526.1 - 6.5e-34 117.8 38.7 6.5e-34 117.8 26.8 3.3 2 1 0 2 2 2 1 Timeless protein C terminal region MFS_1 PF07690.11 EGO60527.1 - 2.7e-44 151.3 48.3 8.8e-44 149.6 33.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO60527.1 - 3.3e-18 65.5 12.3 3.3e-18 65.5 8.5 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EGO60527.1 - 2.4e-07 29.3 13.5 2.4e-07 29.3 9.4 2.1 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EGO60528.1 - 2.7e-34 118.4 85.3 1.7e-26 92.7 33.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGO60528.1 - 3.8e-06 26.6 7.6 0.019 14.7 1.3 3.7 3 0 0 3 3 3 3 MFS_1 like family Sugar_tr PF00083.19 EGO60528.1 - 2.5e-05 23.0 45.7 2.7e-05 22.9 10.2 2.8 1 1 1 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.13 EGO60529.1 - 3.1e-13 49.2 0.1 4.3e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAF-AH_p_II PF03403.8 EGO60530.1 - 3.6e-44 150.5 0.0 1e-42 145.8 0.0 2.2 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EGO60530.1 - 1.4e-10 41.0 0.0 2.4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO60530.1 - 0.00033 20.5 0.2 0.00085 19.2 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO60530.1 - 0.0025 17.6 0.0 0.0063 16.3 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 EGO60530.1 - 0.0032 16.4 0.0 0.0058 15.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EGO60530.1 - 0.0068 15.2 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase DLH PF01738.13 EGO60530.1 - 0.0086 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family UCH PF00443.24 EGO60531.1 - 3.1e-26 92.0 0.1 5.3e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGO60531.1 - 3.3e-12 46.3 0.2 6.5e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EGO60531.1 - 5.5e-05 22.7 0.0 8.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase IF4E PF01652.13 EGO60532.1 - 1.4e-51 174.3 0.1 2e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MTHFR PF02219.12 EGO60533.1 - 1.8e-99 332.4 0.0 2.7e-99 331.8 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Pyridoxal_deC PF00282.14 EGO60533.1 - 0.084 11.2 0.0 0.65 8.3 0.0 1.9 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain DUF3533 PF12051.3 EGO60534.1 - 5.3 5.6 6.1 8 5.0 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) PQ-loop PF04193.9 EGO60535.1 - 9.6e-21 73.1 1.0 1.5e-15 56.4 0.6 2.4 2 0 0 2 2 2 2 PQ loop repeat DUF1065 PF06358.6 EGO60535.1 - 0.015 15.0 0.5 0.033 13.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) UPF0029 PF01205.14 EGO60536.1 - 6.2e-31 106.3 0.0 1.4e-30 105.2 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EGO60536.1 - 1.2e-11 44.4 0.0 2.2e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 EGO60536.1 - 0.12 11.8 0.0 0.63 9.4 0.0 2.1 2 1 0 2 2 2 0 Ubiquitin-conjugating enzyme ACT_7 PF13840.1 EGO60537.1 - 1.4e-21 75.8 0.1 2.3e-15 55.8 0.0 2.4 2 0 0 2 2 2 2 ACT domain Methyltransf_32 PF13679.1 EGO60538.1 - 1.3e-19 70.3 0.0 1.2e-18 67.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain DUF669 PF05037.8 EGO60538.1 - 0.042 13.7 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF669) Hormone_3 PF00159.13 EGO60538.1 - 0.061 13.3 0.1 1.3 9.0 0.0 3.1 2 0 0 2 2 2 0 Pancreatic hormone peptide Peptidase_M19 PF01244.16 EGO60539.1 - 3.1e-111 371.3 0.0 3.9e-111 371.0 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) FCH PF00611.18 EGO60540.1 - 9.1e-17 61.0 0.1 7.6e-16 58.0 0.0 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 EGO60540.1 - 1.2e-16 60.7 0.2 1.4e-15 57.2 0.1 2.3 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.16 EGO60540.1 - 1.4e-11 43.9 0.0 2.9e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Chon_Sulph_att PF06566.6 EGO60540.1 - 0.39 10.3 13.8 0.068 12.7 5.1 2.1 2 0 0 2 2 2 0 Chondroitin sulphate attachment domain RVT_1 PF00078.22 EGO60541.1 - 2.5e-06 27.0 0.0 5.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DAO PF01266.19 EGO60542.1 - 2.5e-65 220.7 0.4 2.9e-65 220.5 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGO60542.1 - 2.4e-06 27.8 0.0 0.015 15.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO60542.1 - 1.7e-05 24.7 0.1 4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EGO60542.1 - 0.0019 16.9 0.6 0.0059 15.2 0.1 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EGO60542.1 - 0.0058 16.5 0.5 3.4 7.4 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 EGO60542.1 - 0.018 13.4 0.3 0.46 8.7 0.0 2.2 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family GMC_oxred_N PF00732.14 EGO60542.1 - 0.079 12.1 0.1 8 5.5 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_9 PF13454.1 EGO60542.1 - 0.13 12.0 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 EGO60542.1 - 0.16 11.0 0.1 0.27 10.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GSHPx PF00255.14 EGO60544.1 - 1.3e-42 143.4 0.1 1.7e-42 143.1 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase DUF4174 PF13778.1 EGO60544.1 - 0.00019 21.5 0.0 0.00029 20.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) AhpC-TSA PF00578.16 EGO60544.1 - 0.0006 19.5 0.1 0.0015 18.2 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGO60544.1 - 0.0072 15.8 0.1 0.014 14.9 0.1 1.8 1 1 0 1 1 1 1 Redoxin GFO_IDH_MocA PF01408.17 EGO60545.1 - 3e-10 40.6 1.6 1.5e-09 38.3 1.1 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EGO60545.1 - 0.12 12.8 0.1 0.22 11.9 0.1 1.5 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DHDPS PF00701.17 EGO60546.1 - 1.3e-32 112.6 0.0 1.4e-32 112.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.3 EGO60548.1 - 8.6e-50 169.4 0.2 2.3e-49 168.0 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO60548.1 - 5.2e-07 29.4 6.9 1.1e-06 28.4 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop16 PF09420.5 EGO60550.1 - 3e-56 190.0 7.8 4.9e-56 189.3 5.4 1.3 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 MARVEL PF01284.18 EGO60551.1 - 5.1e-06 26.3 17.7 7.1e-06 25.8 12.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain Kinesin PF00225.18 EGO60552.1 - 1.2e-111 372.6 1.1 4.3e-111 370.8 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 EGO60552.1 - 7.7e-44 148.7 0.0 2.3e-43 147.2 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein FHA PF00498.21 EGO60552.1 - 7.3e-06 26.0 0.0 5.3e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.3 EGO60552.1 - 6.4e-05 22.9 0.5 0.00018 21.4 0.4 1.9 1 0 0 1 1 1 1 Kinesin protein 1B PH PF00169.24 EGO60552.1 - 0.00029 21.0 0.1 0.017 15.2 0.0 3.2 2 1 0 2 2 2 1 PH domain Peptidase_M1 PF01433.15 EGO60553.1 - 8.1e-75 252.3 0.0 1.1e-74 251.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EGO60553.1 - 1.3e-48 164.2 0.0 2.2e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EGO60553.1 - 8.1e-16 58.2 0.0 1.4e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EGO60553.1 - 0.075 13.0 1.9 0.5 10.3 1.3 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Uds1 PF15456.1 EGO60554.1 - 4.4e-19 68.6 11.3 1e-14 54.5 1.5 2.9 2 1 1 3 3 3 2 Up-regulated During Septation Glyco_hydro_3 PF00933.16 EGO60556.1 - 6.5e-51 173.0 0.1 1.3e-31 109.7 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO60556.1 - 4.3e-30 104.9 0.0 1e-28 100.4 0.0 2.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain G-alpha PF00503.15 EGO60557.1 - 9.4e-119 396.5 0.7 1.1e-118 396.2 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGO60557.1 - 7.3e-14 51.3 1.1 1.3e-08 34.2 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO60557.1 - 0.0018 17.4 0.6 0.49 9.4 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EGO60557.1 - 0.026 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EGO60557.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 EGO60557.1 - 0.13 11.6 0.1 0.34 10.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain Spermine_synth PF01564.12 EGO60558.1 - 4.3e-100 333.6 0.0 6.3e-100 333.1 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EGO60558.1 - 1.1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO60558.1 - 2.3e-05 24.9 0.0 4.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGO60558.1 - 7.4e-05 22.7 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 EGO60558.1 - 0.00088 18.3 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_2 PF00891.13 EGO60558.1 - 0.008 15.3 0.3 0.11 11.7 0.1 2.4 2 1 1 3 3 3 1 O-methyltransferase Methyltransf_23 PF13489.1 EGO60558.1 - 0.014 15.1 0.0 0.053 13.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGO60558.1 - 0.019 15.4 0.2 0.059 13.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EGO60558.1 - 0.057 12.4 0.0 0.098 11.6 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_30 PF05430.6 EGO60558.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EGO60558.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Gyro_capsid PF04162.7 EGO60559.1 - 0.0086 14.3 0.0 0.013 13.7 0.0 1.2 1 0 0 1 1 1 1 Gyrovirus capsid protein (VP1) Gln-synt_C PF00120.19 EGO60560.1 - 9.2e-64 215.0 0.0 1.1e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EGO60560.1 - 4.1e-19 67.9 0.0 7.5e-19 67.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RF-1 PF00472.15 EGO60562.1 - 2.2e-34 117.6 3.7 4.8e-34 116.5 2.6 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EGO60562.1 - 3.5e-30 104.0 0.1 1.5e-29 102.0 0.0 2.1 3 0 0 3 3 3 1 PCRF domain TPR_MLP1_2 PF07926.7 EGO60562.1 - 4.2 7.1 10.7 0.29 10.8 2.8 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Peptidase_S10 PF00450.17 EGO60563.1 - 9.3e-89 298.4 0.2 1.3e-88 297.9 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DWNN PF08783.6 EGO60564.1 - 5.1e-28 96.8 0.0 1e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 DWNN domain DUF605 PF04652.11 EGO60564.1 - 0.0012 18.3 19.6 0.0012 18.3 13.6 2.3 2 0 0 2 2 2 1 Vta1 like zf-CCHC_2 PF13696.1 EGO60564.1 - 0.0022 17.4 5.8 0.0062 16.0 4.0 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGO60564.1 - 0.0045 16.8 1.5 0.01 15.6 1.0 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGO60564.1 - 0.025 14.3 0.2 0.06 13.0 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle U-box PF04564.10 EGO60564.1 - 0.027 14.4 0.0 0.094 12.6 0.0 2.0 1 0 0 1 1 1 0 U-box domain zf-RING_4 PF14570.1 EGO60564.1 - 0.08 12.5 5.8 0.18 11.3 4.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SOBP PF15279.1 EGO60564.1 - 0.17 12.2 26.4 0.063 13.6 12.9 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein Dicty_REP PF05086.7 EGO60564.1 - 0.18 9.4 4.7 0.27 8.9 3.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-Nse PF11789.3 EGO60564.1 - 0.28 10.7 6.3 0.62 9.6 4.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EGO60564.1 - 0.85 9.5 10.7 2.4 8.1 7.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EGO60564.1 - 1.8 8.6 15.9 0.14 12.2 6.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ArsA_ATPase PF02374.10 EGO60566.1 - 6.9e-114 379.9 0.0 7.9e-114 379.8 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EGO60566.1 - 3e-16 59.4 0.2 1.7e-15 56.9 0.1 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGO60566.1 - 3.2e-08 33.6 0.0 3.1e-07 30.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EGO60566.1 - 4.3e-06 26.1 0.0 8.2e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EGO60566.1 - 2.9e-05 23.5 0.5 0.0013 18.2 0.0 2.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EGO60566.1 - 0.0064 15.9 0.0 0.014 14.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGO60566.1 - 0.0093 15.7 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EGO60566.1 - 0.021 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein YhjQ PF06564.7 EGO60566.1 - 0.024 13.9 0.0 0.059 12.7 0.0 1.6 1 0 0 1 1 1 0 YhjQ protein MipZ PF09140.6 EGO60566.1 - 0.025 13.6 0.0 0.051 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase MipZ NB-ARC PF00931.17 EGO60566.1 - 0.045 12.5 0.0 0.07 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 EGO60566.1 - 0.1 12.9 0.2 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EGO60566.1 - 0.13 11.1 0.0 0.37 9.6 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.11 EGO60566.1 - 0.15 11.2 0.0 0.39 9.9 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein TRAPPC9-Trs120 PF08626.6 EGO60567.1 - 4.6e-141 471.4 0.0 5.8e-140 467.7 0.0 2.2 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit adh_short PF00106.20 EGO60567.1 - 6.9e-09 35.8 0.0 2e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO60567.1 - 2e-06 27.7 0.0 3.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO60567.1 - 0.0036 16.9 0.0 0.034 13.8 0.0 2.4 2 0 0 2 2 2 1 KR domain Chorismate_bind PF00425.13 EGO60568.1 - 5.6e-66 222.4 0.1 2.1e-65 220.6 0.1 1.9 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EGO60568.1 - 1e-20 73.9 0.0 2.6e-19 69.4 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EGO60568.1 - 1.8e-10 40.9 0.0 5.3e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EGO60568.1 - 0.0013 18.1 0.5 0.22 10.9 0.1 2.3 2 0 0 2 2 2 2 Peptidase C26 Vps55 PF04133.9 EGO60569.1 - 1.9e-44 150.2 8.5 2.1e-44 150.1 5.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Proteasome PF00227.21 EGO60570.1 - 1.8e-50 170.8 0.0 2.3e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGO60570.1 - 2.9e-11 42.4 0.2 4.8e-11 41.7 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Lysine_decarbox PF03641.9 EGO60571.1 - 4.8e-31 107.3 0.0 8.1e-31 106.5 0.0 1.4 1 1 0 1 1 1 1 Possible lysine decarboxylase Spt5-NGN PF03439.8 EGO60571.1 - 0.1 12.3 0.1 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Early transcription elongation factor of RNA pol II, NGN section CLPTM1 PF05602.7 EGO60572.1 - 1.7e-166 554.3 0.2 2e-166 554.0 0.1 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF4614 PF15391.1 EGO60573.1 - 4.8 6.9 10.9 3.6 7.3 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) ASXH PF13919.1 EGO60574.1 - 9.8e-20 70.7 0.3 3.9e-19 68.8 0.0 2.1 2 0 0 2 2 2 1 Asx homology domain HC2 PF07382.6 EGO60574.1 - 1.8e-09 37.7 22.6 1.8e-09 37.7 15.7 3.2 4 2 0 4 4 4 1 Histone H1-like nucleoprotein HC2 Elong_Iki1 PF10483.4 EGO60575.1 - 7.8e-91 304.3 0.0 9.1e-91 304.0 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF1777 PF08648.7 EGO60576.1 - 1.9e-23 83.1 27.0 1.9e-23 83.1 18.7 5.5 2 2 2 4 4 4 1 Protein of unknown function (DUF1777) SMAP PF15477.1 EGO60576.1 - 2.5e-15 56.4 5.0 2.5e-15 56.4 3.5 6.9 4 2 0 4 4 4 1 Small acidic protein family RAMP4 PF06624.7 EGO60577.1 - 2.8e-05 23.5 0.1 3.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF3094 PF11293.3 EGO60577.1 - 0.049 13.1 0.1 0.069 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) TIM21 PF08294.6 EGO60577.1 - 0.21 11.2 1.5 0.24 11.0 0.7 1.3 1 1 0 1 1 1 0 TIM21 DUF4239 PF14023.1 EGO60578.1 - 0.039 13.3 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF3138 PF11336.3 EGO60578.1 - 0.077 11.1 1.3 0.093 10.8 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2305 PF10230.4 EGO60578.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF2681 PF10883.3 EGO60578.1 - 0.2 11.8 1.3 0.37 11.0 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) FlxA PF14282.1 EGO60578.1 - 0.26 11.2 7.2 0.16 11.9 2.3 2.0 2 0 0 2 2 2 0 FlxA-like protein Mid1 PF12929.2 EGO60579.1 - 2.9e-127 424.9 6.5 3.6e-127 424.6 4.5 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EGO60579.1 - 0.31 11.3 3.7 1.6 9.1 0.4 2.7 3 0 0 3 3 3 0 Fz domain TB2_DP1_HVA22 PF03134.14 EGO60580.1 - 1.2e-31 108.2 5.4 1.7e-31 107.7 3.8 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4407 PF14362.1 EGO60580.1 - 0.027 13.4 0.7 1.4 7.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2207 PF09972.4 EGO60580.1 - 0.13 10.8 2.0 0.16 10.4 1.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Kei1 PF08552.6 EGO60580.1 - 0.59 9.7 5.8 0.64 9.6 1.8 2.0 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Bestrophin PF01062.16 EGO60580.1 - 6.9 5.5 8.5 25 3.6 5.9 1.7 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel RFX_DNA_binding PF02257.10 EGO60581.1 - 4.5e-30 103.6 0.1 1.1e-29 102.4 0.1 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain Hydrolase_4 PF12146.3 EGO60582.1 - 7.2e-20 70.6 0.0 6.9e-19 67.4 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EGO60582.1 - 3.8e-17 62.9 0.1 5.5e-17 62.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO60582.1 - 4.7e-14 52.3 0.0 7.6e-14 51.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO60582.1 - 4.1e-05 23.2 0.0 0.00011 21.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EGO60582.1 - 0.011 15.2 0.0 2.7 7.3 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EGO60582.1 - 0.017 14.3 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.8 EGO60582.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.15 EGO60582.1 - 0.11 11.8 0.0 0.49 9.7 0.0 1.8 2 0 0 2 2 2 0 Putative esterase Cation_efflux PF01545.16 EGO60583.1 - 8e-30 103.8 5.4 9.4e-30 103.6 3.7 1.0 1 0 0 1 1 1 1 Cation efflux family lci PF12197.3 EGO60583.1 - 0.055 13.0 0.2 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein Transport_MerF PF11431.3 EGO60583.1 - 0.062 12.9 1.6 0.17 11.5 1.1 1.8 1 0 0 1 1 1 0 Membrane transport protein MerF DUF4212 PF13937.1 EGO60583.1 - 0.63 10.0 3.7 2.1 8.3 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) Glyco_transf_8 PF01501.15 EGO60584.1 - 3.2e-38 131.5 0.0 6.8e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EGO60584.1 - 0.0017 17.7 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative HDA2-3 PF11496.3 EGO60586.1 - 1.9e-22 79.4 0.0 5.1e-19 68.1 0.0 2.5 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 WEMBL PF05701.6 EGO60586.1 - 0.00097 17.7 25.9 0.00097 17.7 17.9 2.1 1 1 0 1 1 1 1 Weak chloroplast movement under blue light NYD-SP28_assoc PF14775.1 EGO60586.1 - 0.27 10.9 3.3 5 6.9 0.0 3.0 3 0 0 3 3 3 0 Sperm tail C-terminal domain IncA PF04156.9 EGO60586.1 - 3.3 7.2 33.0 0.17 11.4 6.2 4.1 2 1 1 3 3 3 0 IncA protein COX5A PF02284.11 EGO60587.1 - 1.6e-40 137.4 0.4 1.9e-40 137.1 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DHC_N1 PF08385.7 EGO60587.1 - 0.077 11.3 0.2 1.8 6.8 0.0 2.0 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 ELO PF01151.13 EGO60588.1 - 1.3e-62 211.3 17.8 1.5e-62 211.1 12.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Metallophos_2 PF12850.2 EGO60592.1 - 1.8e-08 34.3 0.0 3.8e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGO60592.1 - 9.6e-05 21.8 0.0 0.0021 17.5 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase F-box-like PF12937.2 EGO60593.1 - 2.9e-05 23.6 0.3 8.8e-05 22.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO60593.1 - 7.5 6.3 7.9 14 5.4 2.9 2.9 2 1 0 2 2 2 0 F-box domain Glycogen_syn PF05693.8 EGO60594.1 - 0 1168.7 0.0 0 1168.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EGO60594.1 - 5.3e-06 25.9 0.0 0.01 15.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EGO60594.1 - 9.3e-06 25.3 0.1 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 EGO60594.1 - 0.00018 21.6 0.0 0.00039 20.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Pkinase PF00069.20 EGO60597.1 - 4.6e-71 239.0 0.0 7.8e-71 238.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO60597.1 - 1.7e-35 122.3 0.0 2.9e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO60597.1 - 0.00017 20.6 0.1 0.00058 18.9 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EGO60597.1 - 0.079 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.3 EGO60597.1 - 0.31 10.4 0.0 0.54 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 zf-RanBP PF00641.13 EGO60598.1 - 2e-18 65.1 13.3 7e-11 41.0 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EGO60598.1 - 1.2e-08 34.4 0.0 2.5e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EGO60598.1 - 3.4e-08 33.9 0.0 5.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 EGO60598.1 - 6.3e-06 26.0 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 EGO60598.1 - 2.5 7.9 10.5 0.71 9.7 0.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon Pmp3 PF01679.12 EGO60600.1 - 8.4e-21 73.4 8.4 1e-20 73.1 5.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RIB43A PF05914.7 EGO60602.1 - 0.011 14.3 0.7 0.023 13.3 0.5 1.4 1 0 0 1 1 1 0 RIB43A TFIIA PF03153.8 EGO60602.1 - 4.5 7.0 23.2 0.28 11.0 11.9 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 EGO60603.1 - 2.6e-34 115.8 2.8 4.1e-08 32.8 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EGO60603.1 - 6.1e-31 106.1 0.3 1.6e-30 104.8 0.2 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex SGL PF08450.7 EGO60603.1 - 0.00074 18.9 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Nucleoporin_N PF08801.6 EGO60603.1 - 0.092 11.4 0.5 0.4 9.3 0.4 2.0 1 1 1 2 2 2 0 Nup133 N terminal like XRN_N PF03159.13 EGO60604.1 - 3.2e-103 344.2 0.1 5.6e-103 343.4 0.1 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus SPC22 PF04573.7 EGO60605.1 - 1.7e-33 115.3 3.8 3.1e-23 81.9 0.6 2.0 2 0 0 2 2 2 2 Signal peptidase subunit Hid1 PF12722.2 EGO60606.1 - 6.3e-246 818.3 0.0 2.8e-245 816.1 0.0 1.7 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EGO60606.1 - 5.6e-79 266.0 0.0 1e-50 172.6 0.0 2.0 2 0 0 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein MEKHLA PF08670.6 EGO60606.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 MEKHLA domain EHN PF06441.7 EGO60607.1 - 8.6e-19 67.5 0.0 1.7e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus NPCC PF08058.6 EGO60608.1 - 5.4e-31 107.3 0.0 1.6e-30 105.8 0.0 1.7 1 1 0 1 1 1 1 Nuclear pore complex component Baculo_11_kDa PF06143.6 EGO60609.1 - 0.013 14.8 1.0 0.015 14.6 0.3 1.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family PMP1_2 PF08114.6 EGO60609.1 - 0.029 13.8 1.0 0.04 13.4 0.7 1.3 1 0 0 1 1 1 0 ATPase proteolipid family TMEM154 PF15102.1 EGO60609.1 - 0.058 13.0 0.1 0.058 13.0 0.1 1.1 1 0 0 1 1 1 0 TMEM154 protein family Herpes_gE PF02480.11 EGO60609.1 - 0.1 10.8 0.4 0.095 10.9 0.3 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PspB PF06667.7 EGO60609.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Phage shock protein B dCMP_cyt_deam_1 PF00383.17 EGO60610.1 - 1.8e-26 91.7 1.3 2.7e-26 91.1 0.9 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.1 EGO60610.1 - 8.8e-08 32.5 0.4 5.6e-07 29.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO60610.1 - 3.4e-07 31.1 0.3 1.6e-06 28.8 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO60610.1 - 0.00072 19.4 0.2 0.0019 18.0 0.2 1.8 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 EGO60610.1 - 0.0054 16.1 0.1 0.012 15.0 0.1 1.6 1 0 0 1 1 1 1 Dephospho-CoA kinase Dynamin_N PF00350.18 EGO60610.1 - 0.0077 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin family XOO_2897-deam PF14440.1 EGO60610.1 - 0.018 14.7 0.1 0.039 13.6 0.1 1.6 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase AAA_28 PF13521.1 EGO60610.1 - 0.1 12.5 1.1 0.33 10.8 0.2 2.3 2 1 0 2 2 2 0 AAA domain ThiF PF00899.16 EGO60611.1 - 1.3e-30 105.9 0.0 2.5e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EGO60611.1 - 0.012 15.6 0.0 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3405 PF11885.3 EGO60614.1 - 5.5e-157 522.9 0.2 4.7e-101 338.4 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) LIM PF00412.17 EGO60615.1 - 2.5e-22 78.6 15.6 2e-12 46.9 2.7 2.2 2 0 0 2 2 2 2 LIM domain c-SKI_SMAD_bind PF08782.5 EGO60615.1 - 1.2 9.3 8.9 0.9 9.6 2.1 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain NAD_binding_5 PF07994.7 EGO60618.1 - 3.2e-114 381.3 0.1 4.3e-114 380.9 0.1 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EGO60618.1 - 5.7e-45 151.7 0.2 1.2e-44 150.6 0.2 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase tRNA_anti-codon PF01336.20 EGO60619.1 - 0.00035 20.3 0.0 0.015 15.1 0.0 2.6 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain Pec_lyase_N PF04431.8 EGO60619.1 - 0.15 12.1 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 Pectate lyase, N terminus AMP-binding PF00501.23 EGO60620.1 - 2.7e-82 276.4 0.0 3.1e-82 276.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO60620.1 - 1e-09 39.1 0.0 2.9e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peripla_BP_6 PF13458.1 EGO60620.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Translin PF01997.11 EGO60621.1 - 5.6e-48 163.1 0.1 6.5e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.17 EGO60621.1 - 0.16 11.6 0.3 0.97 9.1 0.0 2.2 2 1 1 3 3 3 0 GMP synthase C terminal domain PIG-F PF06699.6 EGO60622.1 - 6.8e-58 195.7 1.8 9.5e-58 195.2 1.3 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Bacteriocin_IIc PF10439.4 EGO60622.1 - 0.94 9.6 9.6 1.1 9.4 3.0 2.6 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Mito_carr PF00153.22 EGO60623.1 - 5.2e-57 189.5 0.7 1.9e-19 69.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L22e PF01776.12 EGO60624.1 - 6.1e-46 155.0 0.3 7.6e-46 154.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family MMR_HSR1_C PF08438.5 EGO60626.1 - 4.8e-33 113.6 0.0 9.6e-33 112.6 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EGO60626.1 - 1.2e-15 57.5 0.0 2.6e-15 56.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO60626.1 - 3.2e-05 23.2 0.1 0.0014 17.9 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGO60626.1 - 0.0011 18.7 0.5 0.11 12.2 0.1 3.0 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 EGO60626.1 - 0.0058 16.0 0.3 0.63 9.4 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.7 EGO60626.1 - 0.092 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AIG1 PF04548.11 EGO60626.1 - 0.11 11.5 0.1 0.42 9.6 0.0 1.9 2 0 0 2 2 2 0 AIG1 family SET PF00856.23 EGO60627.1 - 0.001 19.3 0.0 0.0029 17.9 0.0 1.7 2 0 0 2 2 2 1 SET domain Fungal_trans PF04082.13 EGO60629.1 - 4.1e-33 114.3 0.2 7.7e-33 113.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO60629.1 - 4e-08 33.0 14.9 4e-08 33.0 10.3 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC-167 PF15188.1 EGO60629.1 - 0.15 11.9 2.3 0.52 10.2 1.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Suf PF05843.9 EGO60629.1 - 1.3 8.6 15.2 3.1 7.4 10.6 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Macoilin PF09726.4 EGO60629.1 - 4.9 5.3 14.2 3 6.0 0.1 2.1 2 0 0 2 2 2 0 Transmembrane protein GDPD PF03009.12 EGO60632.1 - 4.4e-27 95.2 0.0 7.3e-27 94.4 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EGO60632.1 - 0.039 14.1 5.5 0.49 10.6 3.8 2.5 1 1 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family DUF676 PF05057.9 EGO60633.1 - 4.4e-56 189.6 0.0 7.1e-56 188.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EGO60633.1 - 3.7e-06 26.7 0.0 7.7e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO60633.1 - 7.2e-05 22.7 0.3 0.00025 20.9 0.0 1.9 2 2 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EGO60633.1 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EGO60633.1 - 0.026 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein HhH-GPD PF00730.20 EGO60634.1 - 4.3e-16 59.1 0.0 1.1e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EGO60634.1 - 1.5e-08 33.8 0.0 3.7e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif ADH_N PF08240.7 EGO60635.1 - 8.6e-29 99.4 1.4 1.8e-28 98.4 1.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGO60635.1 - 9.7e-21 73.6 0.1 1.8e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGO60635.1 - 0.0028 16.8 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 EGO60635.1 - 0.019 15.8 0.0 0.048 14.5 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase F420_oxidored PF03807.12 EGO60635.1 - 0.02 15.2 0.2 0.14 12.5 0.0 2.5 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 EGO60635.1 - 0.53 10.1 2.4 6.4 6.6 0.9 2.3 1 1 1 2 2 2 0 ThiF family zf-AN1 PF01428.11 EGO60636.1 - 4.3e-10 39.3 11.1 5.8e-10 38.8 7.7 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Phospholip_A2_3 PF09056.6 EGO60637.1 - 3.1e-45 152.9 1.3 3.9e-45 152.6 0.9 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Nucleopor_Nup85 PF07575.8 EGO60638.1 - 3e-12 45.5 0.4 1.1e-10 40.3 0.3 2.7 1 1 0 1 1 1 1 Nup85 Nucleoporin Nic96 PF04097.9 EGO60638.1 - 0.0066 14.6 0.3 0.22 9.6 0.0 2.4 3 0 0 3 3 3 2 Nup93/Nic96 SAM_2 PF07647.12 EGO60639.1 - 4.8e-15 55.1 0.0 7.8e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 EGO60639.1 - 7.6e-14 51.0 0.0 1.6e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGO60639.1 - 3.6e-12 45.4 0.0 8.7e-12 44.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 EGO60639.1 - 3.3e-08 33.6 0.0 7.7e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.12 EGO60639.1 - 7.9e-06 25.2 0.0 1.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 EGO60639.1 - 7e-05 23.0 0.1 0.00021 21.5 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Gastrin PF00918.12 EGO60639.1 - 0.035 14.9 2.2 0.054 14.3 0.1 2.4 2 0 0 2 2 2 0 Gastrin/cholecystokinin family SAM_1 PF00536.25 EGO60639.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) ECH PF00378.15 EGO60640.1 - 7.9e-36 123.4 0.3 2.1e-35 122.0 0.2 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EGO60640.1 - 0.0099 16.0 0.1 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region WBP-1 PF11669.3 EGO60641.1 - 0.018 15.1 0.1 0.09 12.8 0.0 2.2 2 0 0 2 2 2 0 WW domain-binding protein 1 Ran_BP1 PF00638.13 EGO60642.1 - 1.4e-16 60.6 0.0 4.5e-16 59.0 0.0 1.7 1 1 0 1 1 1 1 RanBP1 domain SCP2 PF02036.12 EGO60643.1 - 4.3e-24 84.7 0.4 5.3e-24 84.4 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EGO60643.1 - 8e-07 29.0 0.1 1.1e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.1 EGO60643.1 - 0.062 12.6 0.0 0.071 12.4 0.0 1.1 1 0 0 1 1 1 0 Sterol carrier protein domain Pkinase PF00069.20 EGO60648.1 - 8.6e-57 192.2 0.0 1.3e-56 191.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO60648.1 - 8.4e-21 74.1 0.0 1.6e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGO60648.1 - 0.0096 15.6 0.0 0.041 13.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGO60648.1 - 0.079 12.5 0.6 0.18 11.3 0.4 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pex24p PF06398.6 EGO60649.1 - 5.6e-105 351.0 0.0 6.6e-105 350.8 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.7 EGO60649.1 - 0.27 9.3 0.1 0.38 8.8 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) CDC14 PF08045.6 EGO60650.1 - 8e-90 300.4 0.0 9e-90 300.2 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component polyprenyl_synt PF00348.12 EGO60651.1 - 4.1e-72 242.1 0.0 5.2e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Na_H_Exchanger PF00999.16 EGO60652.1 - 0.018 13.5 0.0 0.028 12.9 0.0 1.2 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family SKG6 PF08693.5 EGO60652.1 - 0.034 13.4 1.0 0.068 12.4 0.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1049 PF06305.6 EGO60652.1 - 0.17 11.3 0.9 0.44 10.0 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Ldr_toxin PF13940.1 EGO60652.1 - 0.8 9.5 3.0 0.96 9.2 0.3 2.4 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system GFA PF04828.9 EGO60654.1 - 8.6e-22 76.9 0.0 1.3e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme XPA_N PF01286.13 EGO60654.1 - 0.17 11.5 2.3 6 6.6 0.2 2.3 2 0 0 2 2 2 0 XPA protein N-terminal Nudix_N_2 PF14803.1 EGO60654.1 - 0.5 10.0 0.1 0.5 10.0 0.0 2.6 3 0 0 3 3 3 0 Nudix N-terminal DUF1365 PF07103.6 EGO60655.1 - 1.3e-36 126.0 0.4 1.3e-35 122.7 0.3 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) DUF3382 PF11862.3 EGO60655.1 - 0.046 13.6 3.0 0.31 10.9 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) MBF1 PF08523.5 EGO60656.1 - 3.7e-25 87.7 1.0 3.7e-25 87.7 0.7 1.5 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EGO60656.1 - 9.1e-10 38.2 0.0 2.2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EGO60656.1 - 0.00016 21.6 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EGO60656.1 - 0.00083 19.4 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain YfdX PF10938.3 EGO60656.1 - 0.0056 16.3 0.7 0.0075 15.9 0.5 1.1 1 0 0 1 1 1 1 YfdX protein RVT_thumb PF06817.9 EGO60657.1 - 0.0014 18.1 0.1 0.0037 16.8 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase thumb domain DLH PF01738.13 EGO60658.1 - 1.9e-08 33.8 0.0 1.2e-07 31.2 0.0 2.2 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGO60658.1 - 5.2e-07 29.5 0.3 9.6e-07 28.6 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family ADH_zinc_N PF00107.21 EGO60659.1 - 1.1e-25 89.7 0.1 1.8e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGO60659.1 - 4.6e-20 72.8 0.1 1.3e-19 71.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGO60659.1 - 2.1e-11 43.5 0.0 4.3e-10 39.3 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF735 PF05246.6 EGO60659.1 - 0.026 14.2 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF735) DNA_pol3_a_NI PF14480.1 EGO60659.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I SerH PF06873.6 EGO60660.1 - 0.014 14.0 4.5 0.016 13.8 3.1 1.1 1 0 0 1 1 1 0 Cell surface immobilisation antigen SerH ATG_C PF09333.6 EGO60660.1 - 0.11 12.6 0.6 0.38 10.9 0.0 2.0 1 1 1 2 2 2 0 ATG C terminal domain AMP-binding PF00501.23 EGO60661.1 - 9.9e-78 261.3 0.0 1.2e-77 261.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO60661.1 - 6.4e-12 46.2 0.0 1.6e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain KilA-N PF04383.8 EGO60665.1 - 0.00061 19.3 0.0 0.0087 15.6 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain Kinetocho_Slk19 PF12709.2 EGO60666.1 - 6.6e-24 83.8 8.4 6.6e-24 83.8 5.8 3.9 3 1 1 4 4 4 2 Central kinetochore-associated FlaC_arch PF05377.6 EGO60666.1 - 0.0002 21.1 17.8 0.86 9.5 0.6 5.2 4 1 1 5 5 5 4 Flagella accessory protein C (FlaC) Reo_sigmaC PF04582.7 EGO60666.1 - 0.024 13.8 2.4 0.96 8.5 0.1 2.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Shugoshin_N PF07558.6 EGO60666.1 - 0.4 10.4 2.6 3.6 7.3 0.6 2.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region AAA_13 PF13166.1 EGO60666.1 - 0.75 8.1 17.0 0.17 10.3 9.4 1.5 1 1 0 1 1 1 0 AAA domain Atg14 PF10186.4 EGO60666.1 - 0.82 8.5 27.7 0.26 10.2 7.2 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 NPV_P10 PF05531.7 EGO60666.1 - 1.1 9.5 7.6 1.4e+02 2.8 0.0 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Filament PF00038.16 EGO60666.1 - 1.2 8.5 37.9 1.2 8.5 10.1 2.9 1 1 1 2 2 2 0 Intermediate filament protein V_ATPase_I PF01496.14 EGO60666.1 - 6.5 4.4 22.2 40 1.8 15.0 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Cortex-I_coil PF09304.5 EGO60666.1 - 6.9 6.7 38.0 0.18 11.8 7.0 3.7 1 1 2 3 3 2 0 Cortexillin I, coiled coil DUF4407 PF14362.1 EGO60666.1 - 10 5.0 24.1 1.5 7.6 8.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Aldedh PF00171.17 EGO60667.1 - 1e-14 53.7 12.8 1.3e-10 40.2 6.5 2.7 1 1 1 2 2 2 2 Aldehyde dehydrogenase family MFS_1 PF07690.11 EGO60668.1 - 5.5e-50 170.0 31.6 5.5e-50 170.0 21.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily PUCC PF03209.10 EGO60668.1 - 4.2e-05 22.4 0.6 4.2e-05 22.4 0.4 3.1 2 1 0 2 2 2 1 PUCC protein INO80_Ies4 PF08193.6 EGO60670.1 - 4.9e-83 278.4 13.8 7.4e-83 277.9 9.6 1.3 1 0 0 1 1 1 1 INO80 complex subunit Ies4 CLTH PF10607.4 EGO60672.1 - 1.5e-39 135.0 0.1 2.1e-39 134.5 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EGO60672.1 - 5.2e-21 75.0 0.2 1e-20 74.0 0.1 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EGO60672.1 - 1.4e-05 24.6 0.2 4e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 LisH PCI PF01399.22 EGO60673.1 - 0.00083 19.6 0.0 0.0024 18.1 0.0 1.8 2 0 0 2 2 2 1 PCI domain SNF2_N PF00176.18 EGO60675.1 - 5.7e-55 186.2 0.0 9.5e-55 185.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-PHD-like PF15446.1 EGO60675.1 - 5.1e-33 113.8 1.2 5.1e-33 113.8 0.8 2.2 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain Helicase_C PF00271.26 EGO60675.1 - 1.3e-14 53.8 0.3 5.4e-14 51.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EGO60675.1 - 6.4e-13 48.1 0.5 6.4e-13 48.1 0.4 1.9 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 EGO60675.1 - 1.2e-06 28.0 3.0 0.00024 20.7 0.2 3.8 2 1 1 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 EGO60675.1 - 2.3e-06 27.1 0.0 4.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 EGO60675.1 - 0.028 13.8 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 SpoU_methylase PF00588.14 EGO60676.1 - 1e-27 96.7 0.0 1.7e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family IDO PF01231.13 EGO60678.1 - 1.1e-36 126.1 0.0 2.4e-36 125.1 0.0 1.4 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase GST_C_3 PF14497.1 EGO60679.1 - 0.0005 20.4 0.0 0.00078 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO60679.1 - 0.0021 17.9 0.1 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2731 PF10806.3 EGO60679.1 - 0.0024 18.0 0.1 0.0056 16.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2731) Tom37 PF10568.4 EGO60679.1 - 0.0033 17.6 0.0 0.0087 16.2 0.0 1.8 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Oxygenase-NA PF09859.4 EGO60679.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA NAD_binding_11 PF14833.1 EGO60680.1 - 0.11 12.5 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Vinculin PF01044.14 EGO60680.1 - 0.11 10.5 0.1 0.13 10.2 0.1 1.0 1 0 0 1 1 1 0 Vinculin family adh_short PF00106.20 EGO60681.1 - 3.7e-22 78.9 0.6 6.3e-22 78.2 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO60681.1 - 1.3e-21 77.4 0.1 2.4e-21 76.6 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO60681.1 - 5.5e-10 39.2 0.2 9.4e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 KR domain TPMT PF05724.6 EGO60682.1 - 1.6e-17 63.6 0.3 7.6e-17 61.4 0.2 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 EGO60682.1 - 0.00081 19.9 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EGO60682.1 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_23 PF13489.1 EGO60682.1 - 0.0042 16.8 0.0 0.0065 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO60682.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGO60682.1 - 0.12 12.8 0.0 0.34 11.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain OTU PF02338.14 EGO60683.1 - 3.8e-17 63.0 0.0 3.8e-17 63.0 0.0 2.3 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGO60683.1 - 0.00018 20.9 0.7 0.01 15.2 0.0 2.9 3 0 0 3 3 3 1 Peptidase C65 Otubain CDC27 PF09507.5 EGO60683.1 - 0.62 9.2 20.9 0.92 8.6 14.5 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1996 PF09362.5 EGO60685.1 - 9.9e-79 264.3 1.5 1.4e-78 263.8 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Glyco_hydro_18 PF00704.23 EGO60687.1 - 2.4e-10 40.4 0.0 5.5e-10 39.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 UPF0560 PF10577.4 EGO60687.1 - 0.35 9.0 2.4 0.44 8.7 1.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Med3 PF11593.3 EGO60687.1 - 1.4 8.1 4.7 1.9 7.6 3.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF572 PF04502.8 EGO60690.1 - 3.6e-58 197.3 15.3 1.3e-57 195.4 10.6 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.8 EGO60690.1 - 0.22 10.9 1.3 1.1 8.7 0.1 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF866) Herpes_capsid PF06112.6 EGO60690.1 - 0.64 10.0 6.6 1.3 9.0 4.6 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DDE_Tnp_IS66 PF03050.9 EGO60690.1 - 6.2 5.9 8.5 0.1 11.8 0.8 1.6 2 0 0 2 2 2 0 Transposase IS66 family WD40 PF00400.27 EGO60691.1 - 1.1e-29 101.2 7.4 3.8e-05 23.4 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Glyco_transf_15 PF01793.11 EGO60692.1 - 2e-138 460.8 11.2 2.4e-138 460.6 7.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase NosL PF05573.7 EGO60692.1 - 0.086 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 NosL Spc97_Spc98 PF04130.8 EGO60693.1 - 3.4e-73 246.8 0.1 4.7e-73 246.3 0.1 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 EGO60693.1 - 0.00046 18.4 0.1 0.0029 15.8 0.0 2.2 3 0 0 3 3 3 1 gamma-Tubulin ring complex non-core subunit mod21 Fungal_trans PF04082.13 EGO60694.1 - 1e-13 50.8 0.1 1.6e-13 50.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO60694.1 - 3.6e-08 33.1 9.3 7.3e-08 32.1 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3433 PF11915.3 EGO60699.1 - 5.7e-14 52.0 1.7 2.8e-13 49.8 0.6 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) DUF4366 PF14283.1 EGO60699.1 - 0.044 13.2 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) AIG2 PF06094.7 EGO60700.1 - 4.5e-20 72.0 0.2 6.1e-20 71.6 0.1 1.2 1 0 0 1 1 1 1 AIG2-like family Chitin_bind_3 PF03067.10 EGO60701.1 - 0.00063 20.0 0.0 0.001 19.3 0.0 1.3 1 0 0 1 1 1 1 Chitin binding domain FAT PF02259.18 EGO60702.1 - 2e-74 250.7 6.2 4.4e-74 249.5 4.3 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EGO60702.1 - 3.3e-24 85.6 0.2 2.5e-23 82.7 0.1 2.6 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EGO60702.1 - 9.8e-08 31.3 0.2 2.9e-07 29.8 0.1 1.9 1 0 0 1 1 1 1 FATC domain Glycolytic PF00274.14 EGO60702.1 - 0.047 12.0 0.0 0.11 10.8 0.0 1.5 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I DUF3138 PF11336.3 EGO60702.1 - 4.9 5.2 4.2 8 4.5 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) AMP-binding PF00501.23 EGO60703.1 - 5.6e-50 169.9 0.0 8.9e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGO60703.1 - 0.013 16.4 0.0 0.025 15.5 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Esterase_phd PF10503.4 EGO60703.1 - 0.022 14.0 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase TPR_11 PF13414.1 EGO60704.1 - 1e-33 114.7 12.7 3e-10 39.6 0.1 7.9 5 2 4 9 9 9 7 TPR repeat TPR_2 PF07719.12 EGO60704.1 - 1.4e-31 105.8 18.3 0.00021 20.9 0.0 10.7 11 0 0 11 11 10 6 Tetratricopeptide repeat Apc3 PF12895.2 EGO60704.1 - 2.3e-29 101.3 14.9 2.6e-19 69.1 1.0 5.9 4 2 3 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EGO60704.1 - 1.4e-28 97.3 17.2 2.8e-05 23.5 0.8 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 EGO60704.1 - 5.2e-27 93.9 17.7 0.00027 21.2 0.1 8.5 5 3 4 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 EGO60704.1 - 1.6e-23 82.4 23.2 8.3e-11 41.6 0.2 8.8 6 4 3 9 9 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGO60704.1 - 9.9e-22 75.4 20.4 0.00032 21.0 0.0 10.7 6 2 6 12 12 11 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGO60704.1 - 1.2e-20 73.6 21.4 6.6e-09 36.2 0.2 7.8 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 EGO60704.1 - 1.1e-16 59.2 4.8 0.0035 17.0 0.4 8.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_10 PF13374.1 EGO60704.1 - 1.3e-15 56.7 13.6 0.0016 18.2 0.0 7.7 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 EGO60704.1 - 2e-13 49.0 12.5 0.091 12.6 0.0 8.8 10 1 1 11 11 11 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGO60704.1 - 1.6e-10 40.6 10.7 0.2 12.2 0.3 8.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 EGO60704.1 - 4.7e-08 32.7 13.9 0.51 10.9 0.1 8.6 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGO60704.1 - 1.7e-07 30.9 8.5 0.32 10.8 0.4 6.0 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGO60704.1 - 2e-07 30.6 7.9 1.5 9.2 0.0 8.8 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_15 PF13429.1 EGO60704.1 - 9.9e-06 24.8 6.1 0.021 13.9 0.0 5.8 3 2 4 8 8 8 1 Tetratricopeptide repeat TPR_3 PF07720.7 EGO60704.1 - 0.00024 20.8 0.6 7.8 6.4 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.2 EGO60704.1 - 0.00097 19.1 0.1 0.0072 16.3 0.0 2.6 2 0 0 2 2 2 1 Tetratrico peptide repeat TPR_21 PF09976.4 EGO60704.1 - 0.0024 17.8 17.1 0.74 9.7 0.2 5.4 6 1 0 6 6 5 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGO60704.1 - 0.36 10.7 5.5 11 5.9 0.1 4.8 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Alk_phosphatase PF00245.15 EGO60705.1 - 3.5e-68 230.2 0.0 6.4e-68 229.3 0.0 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 EGO60705.1 - 3.7e-07 29.6 0.1 1.2e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 EGO60705.1 - 1.1e-05 24.9 0.5 2.1e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EGO60705.1 - 0.0061 15.0 0.2 0.0089 14.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) FTA4 PF13093.1 EGO60705.1 - 0.14 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CutC PF03932.9 EGO60707.1 - 7.5e-11 41.6 0.0 5.9e-10 38.7 0.0 2.2 1 1 0 1 1 1 1 CutC family PGP_phosphatase PF09419.5 EGO60709.1 - 1.1e-69 233.0 0.0 1.3e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EGO60709.1 - 0.0005 19.7 0.0 0.0012 18.4 0.0 1.6 1 1 0 1 1 1 1 HAD-hyrolase-like ORC2 PF04084.9 EGO60710.1 - 2.2e-100 335.6 0.0 2.8e-100 335.3 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DEAD PF00270.24 EGO60711.1 - 4.1e-47 159.8 0.0 8.9e-46 155.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO60711.1 - 1.3e-28 98.6 0.1 2.7e-28 97.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO60711.1 - 0.0065 16.3 0.0 0.017 14.9 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EGO60711.1 - 0.074 11.4 0.0 0.14 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 EGO60711.1 - 0.18 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Proteasome PF00227.21 EGO60712.1 - 5e-38 130.2 0.0 5.8e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 EGO60713.1 - 2.5e-21 74.6 4.6 6.5e-08 32.1 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EGO60713.1 - 0.00013 20.2 0.1 0.029 12.5 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Peptidase_C48 PF02902.14 EGO60714.1 - 7e-32 110.7 1.2 9.8e-31 107.0 0.0 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain DUF1115 PF06544.7 EGO60715.1 - 4.5e-05 23.1 0.8 0.0015 18.2 0.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) DNA_ligase_A_M PF01068.16 EGO60716.1 - 1.5e-14 53.8 0.2 3.9e-13 49.2 0.1 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGO60716.1 - 1.9e-08 34.3 0.0 3.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DIOX_N PF14226.1 EGO60717.1 - 6.4e-24 84.7 0.1 1e-23 84.0 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGO60717.1 - 4.8e-14 52.4 0.0 8.4e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sec39 PF08314.6 EGO60719.1 - 1.4e-256 853.0 1.3 1.6e-256 852.7 0.9 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.4 EGO60720.1 - 3.8e-07 29.9 0.0 4.9e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 EGO60720.1 - 0.0061 16.6 0.5 0.012 15.6 0.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 EGO60720.1 - 0.04 13.9 0.5 0.04 13.9 0.3 1.4 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb COX17 PF05051.8 EGO60720.1 - 0.061 13.3 0.5 0.11 12.5 0.4 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) NAD_binding_6 PF08030.7 EGO60722.1 - 7.3e-06 25.9 0.1 0.0005 19.9 0.1 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EGO60722.1 - 1.1e-05 25.9 0.1 0.013 16.0 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGO60722.1 - 0.0049 16.9 0.0 0.0092 16.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain SUR7 PF06687.7 EGO60723.1 - 7.2e-26 91.0 14.2 9.8e-26 90.6 9.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EGO60723.1 - 0.00064 19.4 8.0 0.00064 19.4 5.5 2.1 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction MpPF26 PF07666.6 EGO60723.1 - 0.013 15.3 1.3 0.013 15.3 0.9 2.3 2 0 0 2 2 2 0 M penetrans paralogue family 26 Claudin_3 PF06653.6 EGO60723.1 - 0.016 14.9 2.6 0.016 14.9 1.8 2.6 2 1 1 3 3 3 0 Tight junction protein, Claudin-like Serinc PF03348.10 EGO60723.1 - 0.64 8.6 6.2 0.25 10.0 2.7 1.4 2 0 0 2 2 2 0 Serine incorporator (Serinc) Peptidase_S49_N PF08496.5 EGO60723.1 - 1.1 9.0 5.5 12 5.6 0.1 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF2207 PF09972.4 EGO60723.1 - 1.4 7.3 8.6 1.3 7.4 4.3 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.1 EGO60723.1 - 3.8 7.9 7.3 10 6.5 0.1 3.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain ETRAMP PF09716.5 EGO60723.1 - 3.8 7.5 5.2 32 4.5 0.0 3.2 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Xan_ur_permease PF00860.15 EGO60724.1 - 4.9e-07 28.5 11.3 3.5e-06 25.7 2.2 2.8 2 1 0 2 2 2 2 Permease family Sulfate_transp PF00916.15 EGO60724.1 - 0.00079 18.5 2.9 0.00079 18.5 2.0 3.4 2 1 1 3 3 3 1 Sulfate transporter family DUF202 PF02656.10 EGO60724.1 - 1 9.6 0.0 1 9.6 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF202) DUF4501 PF14946.1 EGO60725.1 - 0.0077 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4501) Caps_synth_CapC PF14102.1 EGO60725.1 - 0.04 14.0 0.9 0.04 14.0 0.6 1.7 2 0 0 2 2 2 0 Capsule biosynthesis CapC Arginase PF00491.16 EGO60730.1 - 8.3e-88 294.2 0.0 1e-87 293.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family GST_N_3 PF13417.1 EGO60731.1 - 1.4e-10 41.1 0.4 3.1e-10 40.1 0.3 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO60731.1 - 0.0012 18.6 0.1 0.002 17.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO60731.1 - 0.002 18.0 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGO60731.1 - 0.0085 16.0 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGO60731.1 - 0.042 14.3 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Aft1_HRR PF11787.3 EGO60733.1 - 2.7e-27 95.6 12.9 2.7e-27 95.6 8.9 3.4 2 1 0 2 2 2 1 Aft1 HRR domain Aft1_HRA PF11786.3 EGO60733.1 - 2.7e-27 94.8 12.5 2.7e-27 94.8 8.7 2.7 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_OSA PF11785.3 EGO60733.1 - 6.6e-18 64.9 11.1 6.6e-18 64.9 7.7 4.3 5 0 0 5 5 5 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 EGO60733.1 - 1.4e-13 50.5 6.8 2.5e-13 49.7 4.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGO60733.1 - 4.4e-06 26.4 7.0 1e-05 25.2 4.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Activator_LAG-3 PF11498.3 EGO60733.1 - 0.00046 19.0 15.9 0.031 13.0 6.0 2.3 2 0 0 2 2 2 2 Transcriptional activator LAG-3 bZIP_Maf PF03131.12 EGO60733.1 - 0.0081 16.4 3.2 0.0081 16.4 2.2 2.4 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF3450 PF11932.3 EGO60733.1 - 4.3 6.5 11.5 0.8 8.9 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) MIS13 PF08202.6 EGO60735.1 - 4.6e-80 268.9 0.4 7.4e-80 268.2 0.0 1.5 2 0 0 2 2 2 1 Mis12-Mtw1 protein family DUF904 PF06005.7 EGO60735.1 - 0.17 12.2 2.6 2.2 8.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Sdh5 PF03937.11 EGO60737.1 - 2.7e-23 81.4 0.1 7.2e-23 80.0 0.1 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase EMP24_GP25L PF01105.19 EGO60738.1 - 1.1e-42 145.8 0.0 1.3e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4337 PF14235.1 EGO60738.1 - 0.02 14.7 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) zf-U1 PF06220.7 EGO60739.1 - 6.3e-22 76.8 3.4 9.1e-22 76.3 2.3 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EGO60739.1 - 0.023 14.8 3.5 0.048 13.8 2.4 1.5 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding HD PF01966.17 EGO60740.1 - 0.00019 21.4 0.8 0.00096 19.1 0.2 2.3 2 2 1 3 3 3 1 HD domain Cyclase_polyket PF04673.7 EGO60740.1 - 0.13 12.3 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Polyketide synthesis cyclase Abhydrolase_5 PF12695.2 EGO60741.1 - 1.8e-07 31.0 0.0 5.6e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO60741.1 - 1.9e-05 24.6 0.1 2.9e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF218 PF02698.12 EGO60742.1 - 0.001 18.5 0.0 0.0023 17.4 0.0 1.7 1 1 0 1 1 1 1 DUF218 domain Mur_ligase_C PF02875.16 EGO60743.1 - 0.045 13.7 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Pkinase PF00069.20 EGO60745.1 - 2.8e-62 210.2 0.0 5.1e-62 209.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO60745.1 - 3e-41 141.2 0.0 5.4e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO60745.1 - 0.00074 18.5 0.0 0.0022 16.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGO60745.1 - 0.17 10.9 0.0 0.34 9.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ERG4_ERG24 PF01222.12 EGO60747.1 - 6e-137 456.7 17.8 7e-137 456.4 12.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family TMEM238 PF15125.1 EGO60747.1 - 2.5 8.0 10.5 3.8 7.5 0.6 3.7 3 0 0 3 3 3 0 TMEM238 protein family Menin PF05053.8 EGO60747.1 - 4.3 5.3 5.5 6.9 4.7 3.8 1.2 1 0 0 1 1 1 0 Menin ATP-synt_C PF00137.16 EGO60748.1 - 2.7e-31 107.2 32.0 4.8e-19 68.0 9.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 EGO60748.1 - 0.24 10.9 4.1 0.082 12.4 0.5 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A ABA_GPCR PF12430.3 EGO60748.1 - 0.28 10.2 1.6 3 6.9 0.2 2.1 1 1 0 2 2 2 0 Abscisic acid G-protein coupled receptor Ribosomal_L7Ae PF01248.21 EGO60749.1 - 1e-25 89.0 0.1 1.2e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EGO60749.1 - 1.4e-05 25.0 0.1 6.3e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EGO60749.1 - 0.013 15.2 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Syja_N PF02383.13 EGO60750.1 - 1.1e-100 336.5 0.0 1.6e-100 335.9 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EGO60750.1 - 1.8e-37 127.2 0.0 4.4e-37 125.9 0.0 1.7 1 0 0 1 1 1 1 Inositol phosphatase Fn_bind PF02986.9 EGO60750.1 - 0.075 12.5 0.6 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 Fibronectin binding repeat DUF3115 PF11312.3 EGO60751.1 - 1.7e-98 329.3 0.0 2.2e-98 329.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Transketolase_N PF00456.16 EGO60752.1 - 2.8e-151 503.0 0.1 3.8e-151 502.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EGO60752.1 - 2.7e-47 160.5 0.0 4.3e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGO60752.1 - 1.3e-14 54.1 0.0 2.4e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EGO60752.1 - 2.9e-06 26.4 0.0 0.00052 19.0 0.0 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EGO60752.1 - 0.024 13.3 0.0 0.042 12.5 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Filament PF00038.16 EGO60753.1 - 0.00019 21.0 17.1 0.00019 21.0 11.8 4.9 4 2 2 6 6 6 2 Intermediate filament protein HrpB7 PF09486.5 EGO60753.1 - 0.0015 18.4 0.0 0.0015 18.4 0.0 5.8 5 2 2 7 7 7 1 Bacterial type III secretion protein (HrpB7) Myosin_tail_1 PF01576.14 EGO60753.1 - 0.0016 16.2 38.9 0.0016 16.2 26.9 4.3 4 1 1 5 5 5 2 Myosin tail ADIP PF11559.3 EGO60753.1 - 0.0047 16.8 7.2 0.0047 16.8 5.0 6.4 4 2 3 7 7 7 2 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EGO60753.1 - 0.044 12.9 12.3 0.27 10.3 3.5 2.9 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EGO60753.1 - 0.35 10.6 20.2 0.25 11.1 5.8 3.6 2 2 0 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 EGO60753.1 - 0.78 9.5 16.4 3 7.6 0.2 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Flu_NS2 PF00601.14 EGO60755.1 - 0.063 13.4 0.9 5.8 7.1 0.1 2.9 2 1 1 3 3 3 0 Influenza non-structural protein (NS2) DUF2838 PF10998.3 EGO60756.1 - 3.3e-47 158.9 10.8 3.3e-47 158.9 7.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) SMC_N PF02463.14 EGO60757.1 - 6e-60 202.2 0.0 4.3e-59 199.4 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGO60757.1 - 4.7e-26 91.1 0.0 2.6e-25 88.7 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EGO60757.1 - 2.1e-13 51.0 13.0 2.1e-13 51.0 9.0 6.6 2 2 2 4 4 1 1 AAA domain AAA_21 PF13304.1 EGO60757.1 - 3.1e-09 37.2 14.9 3.5e-05 23.9 0.1 4.0 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EGO60757.1 - 2.5e-08 33.3 0.0 5.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EGO60757.1 - 3.9e-06 26.2 27.4 0.0017 17.5 2.5 5.4 4 1 0 5 5 5 3 Reovirus sigma C capsid protein DUF3552 PF12072.3 EGO60757.1 - 0.00032 19.9 8.3 0.00032 19.9 5.8 8.0 4 2 3 7 7 5 2 Domain of unknown function (DUF3552) SbcCD_C PF13558.1 EGO60757.1 - 0.0046 16.8 0.0 0.023 14.5 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EGO60757.1 - 0.0069 14.9 111.8 0.088 11.2 0.4 6.1 4 2 2 6 6 6 4 AAA domain Spc7 PF08317.6 EGO60757.1 - 0.036 12.7 113.4 0.064 11.9 2.0 7.2 3 2 4 7 7 7 0 Spc7 kinetochore protein ABC_tran PF00005.22 EGO60757.1 - 0.66 10.2 0.0 0.66 10.2 0.0 7.0 4 3 0 5 5 3 0 ABC transporter TFIIE_alpha PF02002.12 EGO60758.1 - 1.1e-14 53.7 0.0 2.3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 EGO60758.1 - 0.074 12.3 1.2 0.48 9.7 0.0 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DNA_pol_lambd_f PF10391.4 EGO60759.1 - 3.2e-22 77.8 1.2 6.3e-22 76.8 0.9 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 EGO60759.1 - 5.8e-21 74.6 0.0 1.8e-20 73.0 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EGO60759.1 - 5.7e-20 70.7 0.0 1.1e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 EGO60759.1 - 7.9e-09 35.5 0.0 2e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 EGO60759.1 - 0.0077 16.3 0.2 0.043 13.9 0.0 2.3 3 0 0 3 3 3 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EGO60759.1 - 0.012 15.9 0.0 0.051 13.9 0.0 2.1 2 0 0 2 2 2 0 Nucleotidyltransferase domain MAPEG PF01124.13 EGO60760.1 - 1e-23 83.3 0.8 1.2e-23 83.1 0.6 1.1 1 0 0 1 1 1 1 MAPEG family Kelch_5 PF13854.1 EGO60761.1 - 3.1e-08 33.4 0.2 3.1e-08 33.4 0.1 3.7 4 0 0 4 4 4 1 Kelch motif SKG6 PF08693.5 EGO60761.1 - 2.4e-05 23.5 0.3 4.6e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_6 PF13964.1 EGO60761.1 - 0.0028 17.7 4.5 4.6 7.5 0.3 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 EGO60761.1 - 0.0066 16.1 5.6 0.97 9.3 0.1 4.2 4 0 0 4 4 4 1 Kelch motif UPF0154 PF03672.8 EGO60761.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Shisa PF13908.1 EGO60761.1 - 0.014 15.6 1.6 0.032 14.4 1.0 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator PAT1 PF09770.4 EGO60761.1 - 0.02 13.1 10.1 0.026 12.7 7.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EphA2_TM PF14575.1 EGO60761.1 - 0.02 15.2 0.0 0.094 13.1 0.0 2.1 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Kelch_4 PF13418.1 EGO60761.1 - 0.15 11.8 9.1 13 5.6 0.1 5.2 5 1 0 5 5 5 0 Galactose oxidase, central domain Kelch_1 PF01344.20 EGO60761.1 - 0.3 10.6 2.9 17 5.0 0.1 3.0 2 0 0 2 2 2 0 Kelch motif DUF4106 PF13388.1 EGO60761.1 - 0.7 8.7 12.3 0.89 8.4 7.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) Beta-APP PF03494.8 EGO60761.1 - 0.88 9.0 3.6 1.9 7.9 2.5 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Suf PF05843.9 EGO60761.1 - 1 9.0 4.4 1.6 8.4 3.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Sec23_trunk PF04811.10 EGO60762.1 - 1.7e-79 266.5 0.0 2.4e-79 266.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGO60762.1 - 2.2e-34 116.9 1.0 3.2e-34 116.4 0.1 1.8 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGO60762.1 - 1e-30 106.0 0.2 1.9e-30 105.1 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGO60762.1 - 3.3e-16 58.5 6.8 6.9e-16 57.5 4.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGO60762.1 - 1.2e-14 53.7 0.0 2.6e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L11_N PF03946.9 EGO60763.1 - 3.9e-18 64.6 0.1 6.2e-18 64.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EGO60763.1 - 7.7e-09 35.5 0.0 1.4e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain ATP_bind_3 PF01171.15 EGO60763.1 - 0.045 13.2 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 PP-loop family Glyco_transf_41 PF13844.1 EGO60764.1 - 1.7e-98 329.6 0.8 1.6e-45 154.9 0.0 4.1 3 1 1 4 4 4 4 Glycosyl transferase family 41 TPR_1 PF00515.23 EGO60764.1 - 6.6e-25 85.6 1.0 0.00025 20.5 0.0 7.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 EGO60764.1 - 3e-23 81.2 1.5 4.9e-07 29.2 0.0 4.9 4 1 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 EGO60764.1 - 1e-19 68.8 0.3 0.0019 17.9 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EGO60764.1 - 3.7e-16 57.6 0.0 0.0025 17.4 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGO60764.1 - 2.6e-15 56.0 0.4 4.4e-06 26.5 0.0 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGO60764.1 - 7.2e-12 44.8 0.7 0.13 12.9 0.0 6.2 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGO60764.1 - 1.5e-11 44.6 1.0 0.0035 17.9 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGO60764.1 - 2.2e-10 39.8 0.1 0.027 14.6 0.0 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO60764.1 - 1.5e-08 34.8 0.1 0.0037 17.5 0.0 4.5 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO60764.1 - 9.9e-08 31.2 0.7 0.32 10.8 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 EGO60764.1 - 1e-07 31.6 8.4 0.079 12.9 0.0 5.8 5 1 1 6 6 5 3 Tetratricopeptide repeat Apc3 PF12895.2 EGO60764.1 - 0.00012 22.1 0.2 0.021 14.9 0.0 3.2 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EGO60764.1 - 0.00014 22.0 0.2 7.1 7.3 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGO60764.1 - 0.0009 18.3 0.0 0.76 8.7 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGO60764.1 - 0.0085 15.9 1.4 3 7.7 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Myb_DNA-binding PF00249.26 EGO60767.1 - 2.9e-27 94.4 0.3 3.6e-15 55.7 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGO60767.1 - 3.8e-20 71.7 0.1 2.7e-14 52.9 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGO60767.1 - 0.02 15.0 3.0 0.7 10.0 0.2 3.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Foie-gras_1 PF11817.3 EGO60768.1 - 0.073 12.5 0.1 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 Foie gras liver health family 1 GvpL_GvpF PF06386.6 EGO60768.1 - 0.73 9.3 4.2 0.27 10.7 0.1 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DASH_Dad3 PF08656.5 EGO60768.1 - 5.2 6.8 6.3 0.58 9.8 0.2 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF2414 PF10309.4 EGO60769.1 - 2.5e-21 75.0 0.0 4.9e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) DUF16 PF01519.11 EGO60770.1 - 0.0032 17.6 3.2 0.0032 17.6 2.2 2.1 2 1 0 2 2 2 1 Protein of unknown function DUF16 OEP PF02321.13 EGO60770.1 - 0.011 15.3 4.6 0.011 15.3 3.2 1.6 2 0 0 2 2 2 0 Outer membrane efflux protein Spectrin PF00435.16 EGO60770.1 - 0.19 11.9 13.0 2.1 8.6 2.1 2.9 1 1 1 2 2 2 0 Spectrin repeat MscS_porin PF12795.2 EGO60770.1 - 0.27 10.5 10.6 0.27 10.5 4.3 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF489 PF04356.7 EGO60770.1 - 0.3 10.6 1.4 0.65 9.5 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF489) IFT57 PF10498.4 EGO60770.1 - 0.47 9.1 9.8 0.68 8.6 6.8 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TBPIP PF07106.8 EGO60770.1 - 0.51 9.8 14.3 1.1 8.7 5.0 2.7 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CorA PF01544.13 EGO60770.1 - 0.61 9.0 13.1 8.1 5.3 9.1 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Snapin_Pallidin PF14712.1 EGO60770.1 - 0.65 10.3 7.0 3.5 8.0 1.8 2.7 2 0 0 2 2 2 0 Snapin/Pallidin DUF4140 PF13600.1 EGO60770.1 - 0.82 10.1 12.6 0.31 11.5 0.9 3.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Tropomyosin_1 PF12718.2 EGO60770.1 - 1 9.1 19.5 3.1 7.6 8.2 2.3 1 1 1 2 2 2 0 Tropomyosin like BLOC1_2 PF10046.4 EGO60770.1 - 1.1 9.4 4.1 1.3 9.2 1.8 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 EGO60770.1 - 1.5 8.9 5.2 1.7 8.7 2.1 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 EGO60770.1 - 2 7.0 11.4 1.9 7.0 7.1 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Muted PF14942.1 EGO60770.1 - 2.2 8.1 15.0 3.8 7.3 5.0 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF1664 PF07889.7 EGO60770.1 - 7.4 6.3 6.4 4.6 7.0 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2849 PF11011.3 EGO60773.1 - 0.054 13.7 0.5 0.093 12.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) Rhomboid PF01694.17 EGO60775.1 - 7.3e-40 136.3 8.8 7.3e-40 136.3 6.1 1.8 2 0 0 2 2 2 1 Rhomboid family ABC2_membrane_5 PF13346.1 EGO60775.1 - 0.89 8.8 12.0 0.62 9.3 0.0 2.7 3 0 0 3 3 3 0 ABC-2 family transporter protein Pet127 PF08634.5 EGO60776.1 - 8e-127 422.0 1.8 1.9e-126 420.8 1.2 1.7 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Cohesin_load PF10345.4 EGO60777.1 - 1.9e-180 601.1 0.1 3.1e-180 600.3 0.1 1.3 1 0 0 1 1 1 1 Cohesin loading factor Abhydrolase_1 PF00561.15 EGO60778.1 - 1.4e-10 41.1 0.0 1.9e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGO60778.1 - 2e-10 40.9 0.0 3.3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO60778.1 - 0.00023 20.9 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EGO60778.1 - 0.028 14.1 0.0 0.079 12.6 0.0 1.7 2 0 0 2 2 2 0 Cutinase phage_tail_N PF08400.5 EGO60779.1 - 0.15 11.7 0.8 0.22 11.2 0.6 1.4 1 1 0 1 1 1 0 Prophage tail fibre N-terminal IGPD PF00475.13 EGO60780.1 - 2.4e-59 199.3 0.3 4.2e-59 198.5 0.3 1.3 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase EphA2_TM PF14575.1 EGO60783.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.3 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain MAP65_ASE1 PF03999.7 EGO60783.1 - 2.2 6.8 10.0 3.3 6.2 6.9 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DER1 PF04511.10 EGO60784.1 - 0.00015 21.3 0.1 0.00017 21.1 0.1 1.1 1 0 0 1 1 1 1 Der1-like family ArgJ PF01960.13 EGO60785.1 - 4.5e-151 502.6 0.4 5.2e-151 502.4 0.3 1.0 1 0 0 1 1 1 1 ArgJ family Rep_fac_C PF08542.6 EGO60786.1 - 5.4e-19 67.9 0.0 1.1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EGO60786.1 - 3.6e-13 49.4 0.0 3.5e-11 43.0 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EGO60786.1 - 7.1e-12 45.6 0.0 1.4e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGO60786.1 - 3.4e-07 30.2 0.0 6.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO60786.1 - 2.5e-06 27.6 0.1 8.2e-05 22.6 0.0 2.5 1 1 2 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EGO60786.1 - 3.4e-05 23.9 0.1 0.03 14.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.10 EGO60786.1 - 3.9e-05 22.5 0.0 0.032 12.9 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EGO60786.1 - 6.9e-05 22.0 0.0 0.00018 20.6 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 EGO60786.1 - 0.0001 21.8 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EGO60786.1 - 0.00014 21.5 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EGO60786.1 - 0.00043 19.8 0.0 0.045 13.1 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain AAA_25 PF13481.1 EGO60786.1 - 0.00061 19.2 0.0 0.042 13.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 EGO60786.1 - 0.0013 18.3 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 EGO60786.1 - 0.0014 18.3 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EGO60786.1 - 0.0032 16.6 0.0 0.032 13.3 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_gamma3 PF12169.3 EGO60786.1 - 0.0055 16.4 0.3 0.73 9.5 0.0 2.7 3 0 0 3 3 2 1 DNA polymerase III subunits gamma and tau domain III NTPase_1 PF03266.10 EGO60786.1 - 0.009 15.7 0.3 0.051 13.2 0.0 2.2 2 1 0 3 3 2 1 NTPase AAA_11 PF13086.1 EGO60786.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EGO60786.1 - 0.026 13.9 0.1 0.37 10.2 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 EGO60786.1 - 0.03 13.7 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ArgK PF03308.11 EGO60786.1 - 0.036 12.8 0.0 0.072 11.8 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_31 PF13614.1 EGO60786.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EGO60786.1 - 0.074 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.9 EGO60786.1 - 0.097 12.4 0.1 0.52 10.0 0.0 2.2 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EGO60786.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EGO60786.1 - 0.16 10.9 0.2 1.9 7.4 0.1 2.3 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CN_hydrolase PF00795.17 EGO60787.1 - 7.3e-11 41.7 0.0 1.6e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SnoaL_4 PF13577.1 EGO60788.1 - 2.9e-09 36.8 0.0 3.7e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain CcmD PF04995.9 EGO60790.1 - 0.11 12.2 0.3 0.34 10.6 0.2 1.8 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DKCLD PF08068.7 EGO60791.1 - 1.1e-28 98.9 0.2 7.1e-28 96.3 0.1 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EGO60791.1 - 3.8e-22 79.0 6.2 5.3e-21 75.3 0.1 3.5 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EGO60791.1 - 4.9e-21 74.2 1.2 1e-20 73.2 0.9 1.6 1 0 0 1 1 1 1 PUA domain CT47 PF15623.1 EGO60791.1 - 0.52 9.9 24.2 0.78 9.4 16.7 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 RNA_polI_A34 PF08208.6 EGO60791.1 - 2.9 7.5 33.4 4.7 6.8 23.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.12 EGO60791.1 - 5.8 6.6 10.6 8.8 6.0 7.3 1.2 1 0 0 1 1 1 0 DDHD domain TMEM154 PF15102.1 EGO60792.1 - 0.0025 17.5 0.2 0.0067 16.1 0.1 1.7 1 0 0 1 1 1 1 TMEM154 protein family DUF912 PF06024.7 EGO60792.1 - 0.018 15.0 0.1 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tmemb_9 PF05434.6 EGO60792.1 - 0.024 14.4 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 TMEM9 EphA2_TM PF14575.1 EGO60792.1 - 0.038 14.3 0.4 0.096 13.0 0.3 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CcoS PF03597.10 EGO60792.1 - 0.063 12.7 3.6 0.1 12.0 2.5 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type 7TM_GPCR_Srv PF10323.4 EGO60792.1 - 0.068 12.2 0.3 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv ASFV_J13L PF05568.6 EGO60792.1 - 0.18 11.3 10.2 0.19 11.2 2.5 2.8 2 1 0 2 2 2 0 African swine fever virus J13L protein SAC3_GANP PF03399.11 EGO60793.1 - 5.4e-45 153.4 1.8 7.6e-45 152.9 1.2 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EGO60793.1 - 0.00016 21.4 0.1 0.00039 20.1 0.0 1.6 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 ETC_C1_NDUFA4 PF04800.7 EGO60793.1 - 0.013 15.3 0.4 0.044 13.6 0.0 2.1 2 0 0 2 2 2 0 ETC complex I subunit conserved region F-box-like PF12937.2 EGO60794.1 - 3.2e-10 39.5 0.4 6.9e-10 38.4 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGO60794.1 - 5e-06 26.0 1.3 1.4e-05 24.6 0.9 1.8 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.11 EGO60795.1 - 7.2e-26 90.7 48.5 1.1e-17 63.8 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO60795.1 - 3.5e-24 85.2 20.9 2.3e-18 65.9 4.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter DUF1228 PF06779.9 EGO60795.1 - 0.072 13.1 4.3 0.097 12.7 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Snf7 PF03357.16 EGO60797.1 - 5.8e-32 110.4 15.9 5.8e-32 110.4 11.0 2.0 1 1 1 2 2 2 1 Snf7 PYC_OADA PF02436.13 EGO60797.1 - 0.16 11.3 0.1 0.16 11.3 0.1 2.2 2 1 1 3 3 3 0 Conserved carboxylase domain Allexi_40kDa PF05549.6 EGO60797.1 - 0.24 10.6 4.8 0.38 10.0 3.1 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein Fmp27_WPPW PF10359.4 EGO60797.1 - 1.6 7.0 9.8 2 6.7 6.8 1.3 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TMCO5 PF14992.1 EGO60797.1 - 1.9 7.5 15.6 0.082 12.0 6.9 1.6 2 0 0 2 2 2 0 TMCO5 family DUF3138 PF11336.3 EGO60797.1 - 3.6 5.6 10.1 2.2 6.3 4.1 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3138) RecX PF02631.11 EGO60797.1 - 4.6 7.4 9.3 17 5.6 6.3 2.3 1 1 0 1 1 1 0 RecX family CK2S PF15011.1 EGO60797.1 - 5.3 6.8 8.7 0.25 11.1 1.2 2.1 2 1 1 3 3 3 0 Casein Kinase 2 substrate Ten1 PF12658.2 EGO60798.1 - 3.1e-32 110.9 0.0 3.6e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 EGO60798.1 - 1.8e-05 24.3 0.0 2.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.6 EGO60798.1 - 0.038 13.8 0.1 0.055 13.3 0.1 1.5 1 1 0 1 1 1 0 Replication factor A protein 3 ICE2 PF08426.5 EGO60800.1 - 8.3e-151 502.2 10.8 9.6e-151 502.0 7.5 1.0 1 0 0 1 1 1 1 ICE2 Zw10 PF06248.8 EGO60801.1 - 6.3e-16 57.6 1.4 2e-14 52.7 0.1 2.3 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EGO60801.1 - 0.00029 20.0 0.0 0.0018 17.5 0.0 2.1 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Peptidase_M16_C PF05193.16 EGO60802.1 - 5.2e-24 84.9 0.0 4e-17 62.4 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGO60802.1 - 3.7e-06 26.7 0.0 1.3e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.6 EGO60802.1 - 0.031 13.1 5.9 4.9 5.9 3.0 2.7 3 0 0 3 3 3 0 Peptidase M16C associated DUF4587 PF15248.1 EGO60802.1 - 0.13 12.8 0.4 0.42 11.2 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) Sporozoite_P67 PF05642.6 EGO60802.1 - 0.27 9.0 1.0 0.44 8.3 0.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MarR_2 PF12802.2 EGO60803.1 - 0.068 12.8 0.2 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 MarR family DUF2984 PF11203.3 EGO60803.1 - 0.22 11.6 3.9 0.2 11.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) Acetyltransf_1 PF00583.19 EGO60804.1 - 2.3e-18 66.0 0.0 3.1e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGO60804.1 - 6.5e-08 32.6 0.2 1.4e-07 31.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO60804.1 - 1.4e-06 27.9 0.0 2.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGO60804.1 - 5.6e-06 26.4 0.0 7.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGO60804.1 - 6.6e-06 25.9 0.0 9.2e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGO60804.1 - 1.1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO60804.1 - 2.1e-05 24.4 0.1 2.8e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SNF2_assoc PF08455.5 EGO60804.1 - 0.024 13.2 0.1 0.036 12.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial SNF2 helicase associated NMO PF03060.10 EGO60805.1 - 3.7e-71 239.9 3.4 4.4e-71 239.7 2.3 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGO60805.1 - 2.8e-07 29.7 0.0 0.0024 16.8 0.0 2.6 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EGO60805.1 - 0.061 12.1 3.0 0.11 11.3 2.1 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Taxilin PF09728.4 EGO60807.1 - 9.2e-97 323.8 62.9 1.4e-96 323.2 43.6 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF904 PF06005.7 EGO60807.1 - 0.00077 19.7 9.9 0.00077 19.7 6.8 5.8 3 2 2 5 5 5 2 Protein of unknown function (DUF904) CENP-F_leu_zip PF10473.4 EGO60807.1 - 0.0049 16.7 9.6 0.0049 16.7 6.7 4.5 1 1 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 EGO60807.1 - 1.9 8.2 66.4 0.039 13.6 8.2 5.3 3 2 3 6 6 6 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.6 EGO60807.1 - 2.5 6.7 49.7 0.028 13.0 6.9 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein IncA PF04156.9 EGO60807.1 - 5.2 6.6 59.1 1.1e+03 -1.1 19.2 4.2 1 1 1 2 2 2 0 IncA protein M16C_assoc PF08367.6 EGO60808.1 - 3.5e-61 206.1 0.1 5.2e-61 205.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EGO60808.1 - 6.5e-33 113.9 0.0 7.4e-20 71.4 0.0 3.5 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGO60808.1 - 0.014 15.1 0.1 0.36 10.5 0.0 2.8 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Orn_Arg_deC_N PF02784.11 EGO60809.1 - 5e-82 274.8 0.0 6.9e-82 274.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EGO60809.1 - 1.8e-31 108.2 0.4 5.2e-31 106.7 0.1 1.9 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Pribosyl_synth PF14572.1 EGO60810.1 - 6.8e-34 117.2 2.4 3.2e-22 79.1 0.4 3.2 2 1 1 3 3 3 3 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EGO60810.1 - 1.4e-28 98.9 0.0 1.3e-27 95.8 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EGO60810.1 - 1.6e-13 50.5 0.1 4.1e-13 49.1 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGO60810.1 - 0.022 13.9 0.1 0.036 13.2 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase WD40 PF00400.27 EGO60811.1 - 1.6e-34 116.5 8.1 6.2e-07 29.0 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGO60811.1 - 1.3e-07 31.5 0.1 0.0015 18.2 0.0 3.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A UQ_con PF00179.21 EGO60812.1 - 6.2e-23 80.7 0.0 8.8e-23 80.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF605 PF04652.11 EGO60812.1 - 0.35 10.2 9.7 0.59 9.4 6.8 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EGO60812.1 - 3.2 5.8 6.9 4 5.5 4.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-DHHC PF01529.15 EGO60813.1 - 1.6e-40 138.3 8.5 1.6e-40 138.3 5.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.2 EGO60813.1 - 4.7 7.1 13.4 0.16 11.8 4.7 1.9 2 0 0 2 2 2 0 Double zinc ribbon PI-PLC-X PF00388.14 EGO60814.1 - 2.5e-56 189.1 0.0 4.9e-56 188.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EGO60814.1 - 2.9e-38 130.4 0.0 7.1e-38 129.2 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EGO60814.1 - 1.5e-05 24.7 0.0 3.8e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.6 EGO60814.1 - 4e-05 23.5 0.2 0.0001 22.2 0.2 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PH_8 PF15409.1 EGO60814.1 - 0.011 15.8 0.2 0.11 12.6 0.0 2.5 3 0 0 3 3 3 0 Pleckstrin homology domain DUF328 PF03883.9 EGO60814.1 - 0.027 13.7 0.1 0.062 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF328) RVT_1 PF00078.22 EGO60818.1 - 0.03 13.6 0.2 0.03 13.6 0.2 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ARL2_Bind_BART PF11527.3 EGO60818.1 - 0.11 12.3 1.1 0.12 12.1 0.8 1.2 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART BP28CT PF08146.7 EGO60819.1 - 0.082 12.6 0.1 0.083 12.6 0.1 1.2 1 0 0 1 1 1 0 BP28CT (NUC211) domain DUF1602 PF07673.9 EGO60820.1 - 0.08 12.4 0.8 0.15 11.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1602) B-block_TFIIIC PF04182.7 EGO60824.1 - 9.9e-16 57.3 0.0 2.7e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC DUF2360 PF10152.4 EGO60825.1 - 6.1 7.1 12.1 47 4.2 8.4 2.3 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Cyanate_lyase PF02560.9 EGO60826.1 - 2.2e-32 110.3 0.0 3.2e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Sigma70_r4_2 PF08281.7 EGO60826.1 - 0.00031 20.1 0.0 0.00081 18.7 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_31 PF13560.1 EGO60826.1 - 0.00038 20.5 0.0 0.00066 19.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.1 EGO60826.1 - 0.034 14.3 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_38 PF13936.1 EGO60826.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.11 EGO60826.1 - 0.08 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_3 PF01381.17 EGO60826.1 - 0.086 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix Ebp2 PF05890.7 EGO60827.1 - 2.9e-94 315.3 15.6 2.9e-94 315.3 10.8 1.9 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 GATase_4 PF13230.1 EGO60829.1 - 1.4e-17 63.3 0.0 1.4e-15 56.7 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGO60829.1 - 2.3e-09 37.3 0.0 4.7e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EGO60829.1 - 1.3e-06 27.3 0.0 8.2e-05 21.4 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Dynamin_N PF00350.18 EGO60830.1 - 6.8e-44 149.6 0.0 1.4e-43 148.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EGO60830.1 - 1.1e-11 44.1 0.3 2.3e-11 43.0 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Miro PF08477.8 EGO60830.1 - 0.002 18.6 0.0 0.0098 16.3 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EGO60830.1 - 0.0024 17.8 0.0 0.0078 16.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EGO60830.1 - 0.037 14.0 0.2 0.3 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain STAT_int PF02865.12 EGO60830.1 - 0.053 13.4 2.8 0.19 11.6 0.2 2.8 3 0 0 3 3 3 0 STAT protein, protein interaction domain AAA_21 PF13304.1 EGO60830.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cation_efflux PF01545.16 EGO60831.1 - 4.6e-22 78.4 9.5 1.4e-19 70.3 5.8 2.1 2 0 0 2 2 2 2 Cation efflux family AviRa PF11599.3 EGO60831.1 - 0.015 14.2 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa DUF4131 PF13567.1 EGO60831.1 - 0.28 10.5 2.9 0.4 10.0 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) EI24 PF07264.6 EGO60832.1 - 0.27 10.6 4.5 0.43 9.9 3.1 1.2 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) FSIP1 PF15554.1 EGO60832.1 - 7.4 5.2 5.7 2.1 7.0 0.7 2.1 2 0 0 2 2 2 0 FSIP1 family zf-MYND PF01753.13 EGO60833.1 - 1.6e-07 31.0 20.7 3.9e-07 29.8 14.3 1.7 1 0 0 1 1 1 1 MYND finger PQ-loop PF04193.9 EGO60835.1 - 1.5e-28 98.1 18.7 5.7e-16 57.8 0.2 2.8 3 0 0 3 3 3 2 PQ loop repeat Fun_ATP-synt_8 PF05933.8 EGO60835.1 - 0.086 12.8 0.1 0.086 12.8 0.1 2.4 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) Arm PF00514.18 EGO60836.1 - 3.2e-94 305.9 14.4 1.7e-13 49.8 0.1 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGO60836.1 - 2.9e-25 88.3 0.1 5.4e-10 39.4 0.0 5.7 1 1 4 5 5 5 5 HEAT repeats IBB PF01749.15 EGO60836.1 - 7.2e-23 80.5 0.9 1.2e-22 79.8 0.6 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EGO60836.1 - 8.2e-22 75.2 1.3 3.7e-06 26.5 0.0 7.3 8 0 0 8 8 8 4 HEAT repeat HEAT_EZ PF13513.1 EGO60836.1 - 2e-21 75.8 11.8 3.3e-09 36.9 0.0 6.3 5 1 2 7 7 7 3 HEAT-like repeat Arm_2 PF04826.8 EGO60836.1 - 1.8e-09 37.0 0.0 0.012 14.6 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 EGO60836.1 - 1.4e-05 23.6 0.0 0.0027 16.1 0.0 2.7 1 1 0 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 EGO60836.1 - 0.00018 21.4 0.0 0.94 9.4 0.0 4.6 4 2 0 4 4 4 1 V-ATPase subunit H HEAT_PBS PF03130.11 EGO60836.1 - 0.00031 20.9 0.2 0.66 10.6 0.0 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 EGO60836.1 - 0.005 15.1 0.0 0.36 9.0 0.1 2.9 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit SURF6 PF04935.7 EGO60836.1 - 1.8 7.8 7.6 2.6 7.2 5.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 POT1 PF02765.12 EGO60837.1 - 7.6e-18 64.8 0.0 1.8e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 EGO60837.1 - 0.00021 21.0 0.1 0.071 12.9 0.0 3.3 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain UreD PF01774.12 EGO60838.1 - 1.2e-60 204.5 0.3 9.1e-59 198.4 0.0 2.3 2 0 0 2 2 2 2 UreD urease accessory protein STAG PF08514.6 EGO60838.1 - 6.1e-27 93.6 0.0 1.7e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 EGO60838.1 - 1.9e-06 28.0 0.0 0.0044 17.2 0.0 3.9 2 1 2 4 4 4 3 HEAT repeats RNA_pol_Rpc4 PF05132.9 EGO60839.1 - 1.1e-25 90.1 0.1 1.1e-25 90.1 0.1 2.8 3 0 0 3 3 3 1 RNA polymerase III RPC4 Herpes_capsid PF06112.6 EGO60839.1 - 0.23 11.4 5.4 0.57 10.2 3.7 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Med3 PF11593.3 EGO60839.1 - 0.41 9.8 9.1 1 8.5 3.4 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal CytochromB561_N PF09786.4 EGO60839.1 - 9.8 4.4 6.7 1.1 7.6 0.2 2.3 3 1 1 4 4 4 0 Cytochrome B561, N terminal Zn_clus PF00172.13 EGO60841.1 - 0.00051 19.8 12.5 0.0011 18.8 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 EGO60841.1 - 0.0096 15.1 0.0 0.026 13.7 0.0 1.7 1 0 0 1 1 1 1 Histone chaperone domain CHZ Cyclin_N PF00134.18 EGO60842.1 - 1.8e-43 147.0 0.3 4.1e-43 145.9 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGO60842.1 - 2.8e-31 107.8 0.0 1.2e-30 105.8 0.0 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain Mito_carr PF00153.22 EGO60843.1 - 2.2e-74 245.2 0.3 2.7e-25 87.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EGO60843.1 - 1.1e-13 49.4 2.5 3.1e-06 26.0 0.2 5.5 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 EGO60843.1 - 2.1e-12 46.9 4.5 7.1e-07 29.2 0.3 3.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EGO60843.1 - 3.7e-12 45.0 3.1 2.2e-05 23.9 0.1 5.9 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.1 EGO60843.1 - 1.7e-09 37.1 3.2 0.08 12.5 0.0 5.3 5 1 0 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.1 EGO60843.1 - 6.6e-07 28.3 3.7 7.1e-05 21.9 0.5 3.2 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 EGO60843.1 - 0.03 14.2 0.0 50 3.9 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain DUF1688 PF07958.6 EGO60844.1 - 1e-179 597.5 0.0 1.2e-179 597.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) PLU-1 PF08429.6 EGO60845.1 - 4e-105 351.4 17.2 1.1e-102 343.3 11.1 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EGO60845.1 - 1.9e-43 147.3 0.2 4e-43 146.2 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EGO60845.1 - 2.5e-25 88.1 0.0 8.3e-25 86.4 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 EGO60845.1 - 7.9e-17 60.6 35.2 8.1e-09 35.0 6.9 3.8 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.11 EGO60845.1 - 6.3e-13 48.5 7.1 6.3e-13 48.5 4.9 2.0 2 0 0 2 2 2 1 C5HC2 zinc finger JmjN PF02375.12 EGO60845.1 - 1.8e-11 43.3 2.1 4.2e-11 42.1 1.5 1.7 1 0 0 1 1 1 1 jmjN domain C1_1 PF00130.17 EGO60845.1 - 0.013 15.2 15.2 0.18 11.5 1.9 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EGO60845.1 - 0.21 10.9 17.8 0.032 13.5 4.2 2.8 2 0 0 2 2 2 0 PHD-finger Rubredoxin PF00301.15 EGO60845.1 - 0.82 9.5 12.4 0.2 11.5 2.0 3.3 2 0 0 2 2 2 0 Rubredoxin Prok-RING_1 PF14446.1 EGO60845.1 - 0.87 9.3 19.3 0.025 14.2 2.6 3.5 2 1 0 3 3 3 0 Prokaryotic RING finger family 1 GIY-YIG PF01541.19 EGO60847.1 - 1.9e-07 31.3 0.0 4.5e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H PF13771.1 EGO60847.1 - 0.049 13.7 2.8 0.098 12.8 1.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EGO60847.1 - 0.061 13.3 1.9 0.11 12.5 1.3 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.1 EGO60847.1 - 0.093 12.4 5.1 0.14 11.9 1.7 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 EGO60847.1 - 0.12 12.3 6.8 0.052 13.5 2.5 1.9 2 0 0 2 2 2 0 RING-like domain zf-RING_2 PF13639.1 EGO60847.1 - 0.16 11.8 5.7 0.26 11.1 3.9 1.4 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 EGO60847.1 - 0.36 10.8 2.8 0.8 9.7 1.9 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain DUF3449 PF11931.3 EGO60848.1 - 3.3e-71 238.8 2.1 3e-70 235.7 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EGO60848.1 - 2.1e-12 46.3 0.1 5.3e-12 45.0 0.1 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 EGO60848.1 - 6.2e-11 42.1 2.2 3e-08 33.5 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGO60848.1 - 7.2e-10 38.7 1.2 1.2e-07 31.6 0.4 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EGO60848.1 - 0.00041 20.4 0.2 0.14 12.3 0.0 3.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 EGO60848.1 - 0.0091 15.6 0.2 0.0091 15.6 0.1 3.0 3 1 0 3 3 3 1 DBF zinc finger zf-C2H2_4 PF13894.1 EGO60848.1 - 0.053 13.8 4.7 5.5 7.5 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2175 PF09943.4 EGO60848.1 - 0.061 13.3 1.5 2.2 8.4 0.2 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C2H2 PF00096.21 EGO60848.1 - 1 9.8 3.9 25 5.4 0.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DEAD PF00270.24 EGO60849.1 - 2.4e-41 141.0 0.4 6.2e-41 139.7 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO60849.1 - 4e-29 100.2 0.2 9.1e-29 99.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 EGO60849.1 - 0.0099 15.1 0.6 0.017 14.4 0.1 1.5 2 0 0 2 2 2 1 SecA DEAD-like domain AAA_30 PF13604.1 EGO60849.1 - 0.013 15.0 0.5 0.03 13.9 0.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGO60849.1 - 0.016 14.9 0.2 0.04 13.6 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 EGO60849.1 - 0.023 14.5 0.1 0.064 13.0 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EGO60849.1 - 0.047 13.4 0.2 0.16 11.7 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 EGO60849.1 - 0.11 12.6 1.0 0.49 10.5 0.7 2.0 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 EGO60849.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Helicase Aldo_ket_red PF00248.16 EGO60850.1 - 2.2e-44 151.3 0.0 2.7e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 EGO60851.1 - 1.5e-34 119.2 41.2 2.5e-31 108.6 16.3 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO60851.1 - 1.6e-32 112.6 20.4 3.2e-32 111.6 14.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_A8 PF01252.13 EGO60851.1 - 1.8 8.1 7.9 0.37 10.3 2.3 2.3 2 1 0 2 2 2 0 Signal peptidase (SPase) II Arylesterase PF01731.15 EGO60852.1 - 0.021 14.7 0.0 0.081 12.9 0.0 2.2 2 1 0 2 2 2 0 Arylesterase Radical_SAM PF04055.16 EGO60853.1 - 1.2e-16 61.3 0.0 3.1e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EGO60853.1 - 8.7e-13 48.1 0.0 9.2e-12 44.8 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGO60853.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_binding PF02629.14 EGO60854.1 - 4.6e-26 91.1 3.4 4e-25 88.1 0.2 2.4 2 1 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EGO60854.1 - 5e-23 81.3 0.5 1.2e-22 80.1 0.2 1.7 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.1 EGO60854.1 - 5.4e-07 29.3 0.0 8.9e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EGO60854.1 - 0.0047 17.0 0.1 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 EGO60854.1 - 0.077 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold UQ_con PF00179.21 EGO60855.1 - 1.6e-40 137.7 0.0 2e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EGO60855.1 - 6.2e-07 28.9 0.2 1.1e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EGO60855.1 - 6.4e-05 22.7 0.0 9.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EGO60855.1 - 0.026 14.2 0.1 0.038 13.6 0.1 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 EGO60855.1 - 0.059 13.2 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain AAA PF00004.24 EGO60856.1 - 4.5e-41 140.1 0.0 8.2e-41 139.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGO60856.1 - 5.4e-07 29.8 0.2 0.0002 21.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGO60856.1 - 6.2e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EGO60856.1 - 1e-05 24.5 0.0 1.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EGO60856.1 - 2.2e-05 24.1 0.0 7.1e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGO60856.1 - 0.0002 21.3 0.1 0.001 19.1 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EGO60856.1 - 0.00034 19.7 0.0 0.00063 18.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EGO60856.1 - 0.00079 19.4 0.1 0.0042 17.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGO60856.1 - 0.002 18.0 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGO60856.1 - 0.0024 17.7 0.1 0.022 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGO60856.1 - 0.0037 18.0 0.2 0.011 16.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EGO60856.1 - 0.0061 16.2 0.3 0.35 10.5 0.1 2.7 2 1 0 3 3 3 1 NACHT domain AAA_19 PF13245.1 EGO60856.1 - 0.0064 16.2 0.3 0.015 15.0 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EGO60856.1 - 0.0066 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EGO60856.1 - 0.009 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EGO60856.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EGO60856.1 - 0.013 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EGO60856.1 - 0.021 13.5 0.7 0.045 12.4 0.1 1.8 2 1 0 2 2 2 0 TIP49 C-terminus KaiC PF06745.8 EGO60856.1 - 0.026 13.6 0.2 0.44 9.6 0.1 2.2 1 1 0 2 2 2 0 KaiC PhoH PF02562.11 EGO60856.1 - 0.034 13.3 1.9 0.21 10.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.17 EGO60856.1 - 0.035 12.9 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EGO60856.1 - 0.045 13.9 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EGO60856.1 - 0.049 13.2 0.2 0.14 11.7 0.2 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGO60856.1 - 0.053 12.6 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EGO60856.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EGO60856.1 - 0.24 10.7 5.7 0.24 10.7 0.3 2.6 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.22 EGO60856.1 - 0.25 11.6 1.4 0.82 9.9 0.3 2.6 2 1 0 2 2 1 0 ABC transporter Ribosomal_L13 PF00572.13 EGO60857.1 - 2.5e-28 98.6 0.0 5.8e-28 97.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L13 BAG PF02179.11 EGO60858.1 - 4.1e-17 62.0 0.1 8.9e-17 60.9 0.1 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EGO60858.1 - 5.6e-06 25.6 0.0 1.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EGO60858.1 - 0.0052 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Med21 PF11221.3 EGO60858.1 - 0.065 13.1 0.2 24 4.8 0.0 3.3 2 1 0 3 3 3 0 Subunit 21 of Mediator complex Glutaredoxin PF00462.19 EGO60859.1 - 2e-21 75.7 0.0 4e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 EGO60859.1 - 0.0006 19.3 0.0 0.0007 19.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.1 EGO60859.1 - 0.0033 16.9 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.1 EGO60859.1 - 0.0068 16.5 0.2 0.017 15.3 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.15 EGO60859.1 - 0.014 14.9 0.4 0.28 10.7 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Redoxin PF08534.5 EGO60859.1 - 0.03 13.8 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Redoxin Thioredoxin_3 PF13192.1 EGO60859.1 - 0.036 13.8 0.0 0.056 13.2 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin domain GST_N_3 PF13417.1 EGO60859.1 - 0.051 13.8 0.0 0.068 13.4 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF836 PF05768.9 EGO60859.1 - 0.053 13.7 0.0 0.071 13.3 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Zn_ribbon_2 PF12674.2 EGO60859.1 - 0.064 13.6 0.1 0.094 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative zinc ribbon domain Thioredoxin_4 PF13462.1 EGO60859.1 - 0.089 12.7 0.4 1.4 8.9 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin Thioredoxin PF00085.15 EGO60859.1 - 0.14 11.8 0.1 0.17 11.5 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin Chalcone PF02431.10 EGO60860.1 - 1.3e-63 214.0 0.0 2.2e-63 213.2 0.0 1.4 1 0 0 1 1 1 1 Chalcone-flavanone isomerase F-box-like PF12937.2 EGO60862.1 - 1.3e-10 40.7 0.7 1.3e-10 40.7 0.5 2.3 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 EGO60862.1 - 2.1e-09 36.4 8.4 19 5.7 0.0 11.0 12 0 0 12 12 12 1 Leucine Rich repeat LRR_8 PF13855.1 EGO60862.1 - 8.3e-06 25.4 11.2 0.58 9.9 0.0 5.9 3 1 2 6 6 6 4 Leucine rich repeat F-box PF00646.28 EGO60862.1 - 0.00021 20.8 2.0 0.00031 20.3 0.1 2.3 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.28 EGO60862.1 - 0.0046 16.7 21.8 9.4 6.7 0.2 9.3 8 4 0 8 8 8 1 Leucine Rich Repeat LRR_7 PF13504.1 EGO60862.1 - 5.8 7.5 18.6 39 5.0 0.0 7.8 7 1 0 7 7 7 0 Leucine rich repeat 4HBT PF03061.17 EGO60864.1 - 1.6e-10 40.9 0.1 3.6e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Sod_Fe_C PF02777.13 EGO60866.1 - 6.3e-36 122.4 0.4 1.3e-35 121.4 0.3 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EGO60866.1 - 9.9e-33 112.2 5.3 1e-32 112.2 2.2 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain MUG113 PF13455.1 EGO60868.1 - 1.6e-31 108.5 0.5 3.9e-31 107.3 0.3 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EGO60868.1 - 1.4e-24 86.3 1.3 5.4e-24 84.5 0.9 2.1 1 1 0 1 1 1 1 T5orf172 domain Chorismate_bind PF00425.13 EGO60869.1 - 1.1e-68 231.3 0.0 1.7e-68 230.7 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EGO60869.1 - 1.8e-29 102.5 0.0 3.1e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EGO60869.1 - 3.5e-18 65.9 0.0 7.3e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EGO60869.1 - 3.8e-05 23.2 0.2 0.0015 18.0 0.1 2.8 1 1 0 1 1 1 1 Peptidase C26 DUF2911 PF11138.3 EGO60869.1 - 0.18 11.4 0.1 0.34 10.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) Zn_clus PF00172.13 EGO60870.1 - 1.1e-06 28.4 8.1 2.2e-06 27.4 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4048 PF13257.1 EGO60871.1 - 4.8e-09 36.2 6.5 4.8e-09 36.2 4.5 4.1 3 1 2 5 5 5 2 Domain of unknown function (DUF4048) ATP-synt_ab PF00006.20 EGO60872.1 - 2.1e-113 377.0 0.0 3e-113 376.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGO60872.1 - 1.1e-19 70.9 1.4 2.1e-19 70.0 1.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGO60872.1 - 1.9e-15 56.7 5.7 3.1e-15 56.1 3.1 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 EGO60872.1 - 0.093 12.6 0.0 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain N-SET PF11764.3 EGO60873.1 - 2.9e-42 144.4 0.0 2.9e-42 144.4 0.0 2.8 4 0 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EGO60873.1 - 2e-26 91.0 0.5 4.5e-26 89.9 0.3 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 EGO60873.1 - 7.1e-24 84.9 0.2 7.1e-24 84.9 0.1 3.3 2 2 0 2 2 2 1 SET domain RRM_1 PF00076.17 EGO60873.1 - 0.033 13.8 0.0 0.26 10.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2718 PF10918.3 EGO60874.1 - 0.09 12.8 1.0 0.24 11.4 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) Tropomyosin_1 PF12718.2 EGO60875.1 - 2.4e-52 176.5 35.4 2.8e-52 176.3 24.5 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EGO60875.1 - 2.9e-09 36.3 33.5 1.1e-06 27.9 14.5 2.4 1 1 1 2 2 2 2 Tropomyosin ATG16 PF08614.6 EGO60875.1 - 0.00027 20.8 28.7 0.0011 18.8 7.4 2.5 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF4200 PF13863.1 EGO60875.1 - 0.00037 20.4 33.1 0.07 13.0 9.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.3 EGO60875.1 - 0.00037 20.1 28.3 0.057 13.1 13.8 2.4 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding Myosin_tail_1 PF01576.14 EGO60875.1 - 0.0012 16.7 32.1 0.0015 16.3 22.2 1.2 1 0 0 1 1 1 1 Myosin tail Cast PF10174.4 EGO60875.1 - 0.0014 16.7 28.5 0.0015 16.6 19.8 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone CENP-F_leu_zip PF10473.4 EGO60875.1 - 0.0022 17.8 34.8 0.049 13.4 4.4 2.5 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 EGO60875.1 - 0.0029 16.3 28.8 0.017 13.7 9.4 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein BLOC1_2 PF10046.4 EGO60875.1 - 0.0032 17.5 22.0 0.0096 16.0 3.9 3.5 2 2 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.16 EGO60875.1 - 0.0068 16.3 32.1 0.2 11.6 0.8 4.9 2 2 2 4 4 4 2 bZIP transcription factor KLRAQ PF10205.4 EGO60875.1 - 0.0069 16.3 9.6 0.0069 16.3 6.7 2.5 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein Mod_r PF07200.8 EGO60875.1 - 0.0075 16.1 26.5 0.14 12.1 2.0 2.1 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein GAS PF13851.1 EGO60875.1 - 0.0087 15.2 32.1 0.048 12.8 14.8 2.4 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 EGO60875.1 - 0.0099 15.6 20.1 0.017 14.8 3.1 2.3 1 1 1 2 2 2 1 Laminin Domain II Vps5 PF09325.5 EGO60875.1 - 0.0099 15.1 7.6 0.0099 15.1 5.3 2.9 1 1 0 2 2 2 1 Vps5 C terminal like DUF745 PF05335.8 EGO60875.1 - 0.015 14.8 4.9 0.015 14.8 3.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) EzrA PF06160.7 EGO60875.1 - 0.016 13.4 24.2 0.054 11.6 3.9 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA APG6 PF04111.7 EGO60875.1 - 0.019 14.0 34.9 0.38 9.7 10.7 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 PilJ PF13675.1 EGO60875.1 - 0.022 15.0 13.1 0.17 12.2 2.6 2.6 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Fib_alpha PF08702.5 EGO60875.1 - 0.026 14.6 19.4 0.17 11.9 2.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 EGO60875.1 - 0.029 13.9 33.7 7 6.1 23.3 2.2 1 1 0 1 1 1 0 IncA protein HAP1_N PF04849.8 EGO60875.1 - 0.033 13.1 28.7 0.048 12.6 19.9 1.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Atg14 PF10186.4 EGO60875.1 - 0.033 13.1 25.8 0.073 12.0 11.5 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ERM PF00769.14 EGO60875.1 - 0.039 13.4 35.9 0.16 11.4 10.4 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family LPP PF04728.8 EGO60875.1 - 0.045 13.5 1.5 9.3 6.1 0.0 3.1 2 1 1 3 3 3 0 Lipoprotein leucine-zipper MAD PF05557.8 EGO60875.1 - 0.046 11.8 26.9 0.031 12.3 8.1 2.0 1 1 0 1 1 1 0 Mitotic checkpoint protein Reo_sigmaC PF04582.7 EGO60875.1 - 0.051 12.7 5.0 2.3 7.3 0.0 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EGO60875.1 - 0.052 13.3 37.1 6.2 6.7 7.7 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding HOOK PF05622.7 EGO60875.1 - 0.055 11.2 26.6 0.061 11.1 18.4 1.0 1 0 0 1 1 1 0 HOOK protein Nup54 PF13874.1 EGO60875.1 - 0.063 12.9 23.6 0.06 13.0 7.7 2.7 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 ADIP PF11559.3 EGO60875.1 - 0.07 13.0 32.1 0.096 12.5 8.0 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.7 EGO60875.1 - 0.072 13.3 11.0 16 5.8 0.1 3.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 EGO60875.1 - 0.077 12.5 28.5 1.5 8.3 8.1 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_MLP1_2 PF07926.7 EGO60875.1 - 0.093 12.4 34.8 0.26 11.0 8.1 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein BRE1 PF08647.6 EGO60875.1 - 0.13 12.2 29.3 0.31 11.0 11.4 2.3 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Striatin PF08232.7 EGO60875.1 - 0.17 12.1 25.8 17 5.6 17.9 2.2 1 1 0 1 1 1 0 Striatin family Cortex-I_coil PF09304.5 EGO60875.1 - 0.18 11.8 29.7 0.5 10.4 0.4 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil Jnk-SapK_ap_N PF09744.4 EGO60875.1 - 0.19 11.7 27.6 0.27 11.2 11.2 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.7 EGO60875.1 - 0.25 11.1 16.7 0.3 10.8 1.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 EGO60875.1 - 0.26 11.3 28.8 1.5 8.8 0.5 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3287 PF11690.3 EGO60875.1 - 0.27 11.3 9.1 0.1 12.6 1.1 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3287) CCDC155 PF14662.1 EGO60875.1 - 0.32 10.5 34.4 1.3 8.6 8.5 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Phage_GP20 PF06810.6 EGO60875.1 - 0.32 10.4 27.9 0.26 10.7 9.0 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Lebercilin PF15619.1 EGO60875.1 - 0.37 10.1 31.2 72 2.7 21.7 2.3 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF3584 PF12128.3 EGO60875.1 - 0.42 7.8 27.9 0.47 7.7 19.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mnd1 PF03962.10 EGO60875.1 - 0.42 10.2 31.5 0.68 9.5 9.1 2.2 1 1 1 2 2 2 0 Mnd1 family DUF4482 PF14818.1 EGO60875.1 - 0.49 11.0 27.0 0.15 12.7 1.9 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4482) DUF342 PF03961.8 EGO60875.1 - 0.49 8.7 26.7 0.91 7.8 5.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) WXG100 PF06013.7 EGO60875.1 - 0.53 10.3 16.5 3.2 7.8 0.3 3.4 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Syntaxin-6_N PF09177.6 EGO60875.1 - 0.55 10.6 21.1 3.8 7.9 4.1 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Fmp27_WPPW PF10359.4 EGO60875.1 - 0.56 8.5 24.7 0.19 10.0 5.6 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Filament PF00038.16 EGO60875.1 - 0.59 9.5 28.0 2 7.8 19.4 1.8 1 1 0 1 1 1 0 Intermediate filament protein MCPsignal PF00015.16 EGO60875.1 - 0.64 9.5 13.4 1.2 8.6 0.9 2.0 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain AAA_13 PF13166.1 EGO60875.1 - 0.67 8.3 24.5 1.1 7.6 17.0 1.4 1 1 0 1 1 1 0 AAA domain DUF972 PF06156.8 EGO60875.1 - 0.78 10.1 25.0 2.8e+03 -1.4 17.3 2.8 1 1 0 1 1 0 0 Protein of unknown function (DUF972) CDC37_N PF03234.9 EGO60875.1 - 1.2 9.4 23.6 4.7 7.5 16.3 1.9 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Cep57_MT_bd PF06657.8 EGO60875.1 - 1.3 9.0 21.5 0.2 11.6 0.7 3.6 1 1 1 3 3 2 0 Centrosome microtubule-binding domain of Cep57 DUF4201 PF13870.1 EGO60875.1 - 1.4 8.3 25.7 0.9 8.9 11.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF869 PF05911.6 EGO60875.1 - 1.6 6.8 27.8 0.97 7.5 7.7 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) TMP_2 PF06791.8 EGO60875.1 - 1.6 8.2 6.7 0.35 10.4 1.2 1.9 1 1 1 2 2 2 0 Prophage tail length tape measure protein FlaC_arch PF05377.6 EGO60875.1 - 2.2 8.2 23.7 3.2 7.7 3.4 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) MIS13 PF08202.6 EGO60875.1 - 2.3 7.1 21.9 0.61 9.0 4.3 2.3 1 1 1 2 2 2 0 Mis12-Mtw1 protein family DUF812 PF05667.6 EGO60875.1 - 2.4 6.5 27.6 29 2.9 19.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Rootletin PF15035.1 EGO60875.1 - 2.6 8.0 28.2 0.78 9.6 15.9 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion IFT46_B_C PF12317.3 EGO60875.1 - 2.8 7.2 9.3 2.5 7.4 5.0 1.8 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal rRNA_proc-arch PF13234.1 EGO60875.1 - 3.2 6.8 17.7 0.032 13.4 1.7 2.5 1 1 1 2 2 2 0 rRNA-processing arch domain Ax_dynein_light PF10211.4 EGO60875.1 - 3.5 7.4 31.8 5.9 6.6 4.5 3.3 1 1 2 3 3 3 0 Axonemal dynein light chain HSP70 PF00012.15 EGO60875.1 - 3.7 5.3 19.6 4.8 4.9 13.6 1.3 1 0 0 1 1 1 0 Hsp70 protein MbeD_MobD PF04899.7 EGO60875.1 - 3.9 7.4 11.5 8.8 6.3 0.6 3.2 2 1 1 3 3 3 0 MbeD/MobD like Methyltransf_9 PF08003.6 EGO60875.1 - 4 6.0 7.6 0.6 8.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) DUF724 PF05266.9 EGO60875.1 - 4.2 6.9 29.2 4.2 6.9 8.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) EHN PF06441.7 EGO60875.1 - 4.7 7.1 11.5 1.6 8.7 2.3 2.5 1 1 1 2 2 2 0 Epoxide hydrolase N terminus V_ATPase_I PF01496.14 EGO60875.1 - 5.3 4.7 22.4 4.3 5.0 14.4 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.3 EGO60875.1 - 5.4 6.2 26.3 3.3 6.8 8.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMCO5 PF14992.1 EGO60875.1 - 5.6 6.0 27.9 15 4.5 7.1 2.1 1 1 1 2 2 2 0 TMCO5 family Uds1 PF15456.1 EGO60875.1 - 6.4 6.7 26.0 8.1 6.4 3.7 3.0 1 1 1 2 2 2 0 Up-regulated During Septation Rab5-bind PF09311.6 EGO60875.1 - 7.2 6.4 31.9 15 5.4 22.1 1.5 1 1 0 1 1 1 0 Rabaptin-like protein CENP-Q PF13094.1 EGO60875.1 - 7.3 6.5 37.1 2.5 8.1 10.5 2.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FlxA PF14282.1 EGO60875.1 - 8.2 6.4 24.7 24 4.9 11.1 3.2 1 1 1 2 2 2 0 FlxA-like protein IFT57 PF10498.4 EGO60875.1 - 8.7 4.9 24.5 4.6 5.8 0.9 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF904 PF06005.7 EGO60875.1 - 8.8 6.7 38.8 7 7.0 9.9 3.5 1 1 0 2 2 2 0 Protein of unknown function (DUF904) FliD_N PF02465.13 EGO60875.1 - 9.7 6.6 15.0 2.4 8.5 0.4 3.1 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Nop25 PF09805.4 EGO60876.1 - 7e-36 123.3 15.3 7e-36 123.3 10.6 2.3 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) ATP-synt_S1 PF05827.7 EGO60877.1 - 5.5e-47 160.4 0.0 8e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Trm112p PF03966.11 EGO60878.1 - 2.9e-17 62.7 0.1 3.5e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 EGO60878.1 - 0.012 15.8 0.3 0.022 15.0 0.2 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Pro_isomerase PF00160.16 EGO60879.1 - 2.4e-46 157.7 0.5 3.1e-46 157.4 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Syntaxin-6_N PF09177.6 EGO60880.1 - 1.2e-24 86.4 1.5 2.5e-24 85.5 0.2 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EGO60880.1 - 1.2e-14 53.7 8.9 1e-13 50.7 2.6 3.2 3 0 0 3 3 3 1 SNARE domain TPR_MLP1_2 PF07926.7 EGO60880.1 - 0.023 14.4 2.7 0.44 10.2 0.1 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 EGO60880.1 - 0.21 11.3 2.0 1.9 8.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DegS PF05384.6 EGO60880.1 - 0.22 10.7 2.6 0.61 9.2 0.3 2.5 2 1 0 2 2 2 0 Sensor protein DegS TBPIP PF07106.8 EGO60880.1 - 0.41 10.1 2.0 0.8 9.2 0.1 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3753 PF12575.3 EGO60880.1 - 0.49 10.2 3.5 17 5.3 1.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) DUF1515 PF07439.6 EGO60880.1 - 0.67 9.7 3.5 28 4.5 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) TMF_DNA_bd PF12329.3 EGO60880.1 - 0.91 9.3 4.1 10 6.0 0.0 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.6 EGO60880.1 - 0.96 9.1 4.0 2.9 7.6 0.0 2.8 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 FlxA PF14282.1 EGO60880.1 - 8.2 6.4 11.7 0.32 10.9 1.0 2.4 1 1 1 2 2 2 0 FlxA-like protein GLE1 PF07817.8 EGO60881.1 - 1.9e-20 72.8 0.0 1.5e-19 69.9 0.0 2.0 1 1 0 1 1 1 1 GLE1-like protein CAF-1_p150 PF11600.3 EGO60881.1 - 8.1 5.7 17.5 0.67 9.3 8.6 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RNB PF00773.14 EGO60882.1 - 9.5e-72 242.0 0.0 2.3e-71 240.7 0.0 1.7 1 0 0 1 1 1 1 RNB domain DUF4239 PF14023.1 EGO60882.1 - 0.021 14.2 0.2 0.046 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Ferritin_2 PF13668.1 EGO60883.1 - 1.5e-40 138.2 2.7 2.3e-40 137.6 1.9 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF4439 PF14530.1 EGO60883.1 - 0.0032 17.9 1.6 0.0062 17.0 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4439) ELFV_dehydrog PF00208.16 EGO60884.1 - 1.1e-81 274.0 4.9 1.4e-81 273.6 3.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EGO60884.1 - 9.5e-49 164.3 0.0 2e-48 163.2 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EGO60884.1 - 0.019 15.2 0.2 0.045 14.0 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Semialdhyde_dh PF01118.19 EGO60884.1 - 0.045 14.0 0.1 0.38 11.0 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain GMC_oxred_C PF05199.8 EGO60885.1 - 8.6e-11 42.3 1.1 1.3e-08 35.2 0.2 2.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EGO60885.1 - 3.3e-08 33.0 0.3 2.9e-07 29.9 0.2 2.4 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EGO60885.1 - 0.00018 20.4 1.3 0.00024 20.0 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EGO60885.1 - 0.0011 18.0 0.2 0.028 13.3 0.1 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EGO60885.1 - 0.0034 16.5 0.3 0.0067 15.5 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGO60885.1 - 0.014 15.2 0.1 0.03 14.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO60885.1 - 0.015 15.3 0.5 0.044 13.8 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGO60885.1 - 0.036 12.9 0.1 0.092 11.6 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Abhydrolase_1 PF00561.15 EGO60885.1 - 0.044 13.3 0.0 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF900 PF05990.7 EGO60885.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Pyr_redox PF00070.22 EGO60885.1 - 0.07 13.5 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO60885.1 - 0.071 12.1 0.2 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EGO60885.1 - 0.08 11.7 0.2 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 EGO60885.1 - 0.1 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EGO60885.1 - 0.13 10.6 0.1 0.19 10.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein DNA_pol_B PF00136.16 EGO60886.1 - 7.6e-145 483.2 2.5 1.1e-144 482.7 1.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EGO60886.1 - 7.9e-82 274.7 0.4 2e-81 273.3 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EGO60886.1 - 3.3e-21 75.0 3.4 3.3e-21 75.0 2.3 1.8 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 EGO60886.1 - 0.00012 21.6 0.1 0.00024 20.6 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EGO60886.1 - 0.00073 19.3 1.1 0.0023 17.7 0.2 2.4 2 1 0 2 2 2 1 RNase_H superfamily DNA_pol_B_2 PF03175.8 EGO60886.1 - 0.00081 18.1 1.6 0.62 8.6 0.0 3.2 3 0 0 3 3 3 2 DNA polymerase type B, organellar and viral C1_1 PF00130.17 EGO60886.1 - 0.88 9.3 9.5 0.37 10.5 0.5 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PAT1 PF09770.4 EGO60887.1 - 1.3 7.1 19.4 1.5 6.9 13.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF410 PF04190.8 EGO60888.1 - 2.5e-44 151.8 0.0 3e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) CUE PF02845.11 EGO60890.1 - 0.00053 19.4 0.0 0.0014 18.0 0.0 1.8 1 0 0 1 1 1 1 CUE domain UIM PF02809.15 EGO60890.1 - 0.076 12.6 5.5 0.03 13.8 1.4 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif UQ_con PF00179.21 EGO60891.1 - 3.8e-35 120.3 0.0 4.8e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO60891.1 - 0.0016 18.2 0.0 0.008 15.9 0.0 1.9 1 1 0 1 1 1 1 Prokaryotic E2 family B HGTP_anticodon2 PF12745.2 EGO60892.1 - 9.8e-84 280.7 0.0 9.8e-84 280.7 0.0 2.5 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EGO60892.1 - 1.2e-74 250.7 0.1 3.6e-37 127.9 0.0 4.6 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 EGO60892.1 - 3.2e-48 164.0 0.0 8.9e-22 77.4 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 EGO60892.1 - 2.9e-13 49.5 1.8 5.2e-13 48.7 0.0 2.2 2 1 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.17 EGO60892.1 - 4.6e-12 45.8 0.5 4.6e-12 45.8 0.3 2.2 2 0 0 2 2 2 1 RWD domain YrbL-PhoP_reg PF10707.4 EGO60892.1 - 4.5e-05 22.8 0.0 0.011 15.0 0.0 2.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.18 EGO60892.1 - 0.00013 21.7 1.6 0.45 10.1 0.0 3.2 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EGO60892.1 - 0.00026 20.0 0.0 0.0026 16.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like DUF3360 PF11840.3 EGO60892.1 - 0.29 9.4 0.0 0.45 8.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) Pox_ser-thr_kin PF05445.6 EGO60892.1 - 0.33 9.7 0.4 16 4.1 0.0 2.2 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase UreF PF01730.11 EGO60893.1 - 4.4e-16 59.3 0.2 4.4e-16 59.3 0.1 2.1 2 0 0 2 2 2 1 UreF RRM_1 PF00076.17 EGO60894.1 - 6.7e-09 35.2 0.0 1.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGO60894.1 - 1.4e-08 34.4 0.0 3.5e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGO60894.1 - 3.2e-05 23.8 0.1 7.8e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGO60894.1 - 3.6e-05 23.4 0.0 7.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EGO60894.1 - 0.034 13.8 0.7 0.07 12.8 0.5 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TGS PF02824.16 EGO60895.1 - 1.2e-20 73.0 0.0 2.4e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EGO60895.1 - 1.8e-19 69.8 0.0 4.2e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGO60895.1 - 3.7e-13 49.0 0.0 5.8e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGO60895.1 - 3.7e-05 23.6 0.3 0.034 13.9 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EGO60895.1 - 0.0012 19.2 0.0 0.0034 17.8 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 EGO60895.1 - 0.053 12.2 0.1 0.11 11.2 0.1 1.5 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 EGO60895.1 - 0.066 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family Spo12 PF05032.7 EGO60896.1 - 2.9e-16 58.7 1.2 6.4e-16 57.6 0.8 1.6 1 0 0 1 1 1 1 Spo12 family Nucleoporin_FG PF13634.1 EGO60896.1 - 0.56 10.4 9.9 0.58 10.4 3.6 2.1 2 0 0 2 2 2 0 Nucleoporin FG repeat region Acyl-CoA_dh_1 PF00441.19 EGO60898.1 - 5.4e-29 101.2 0.5 8.7e-29 100.5 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGO60898.1 - 5.8e-16 57.7 0.0 1.2e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGO60898.1 - 1.9e-14 54.0 0.6 3.5e-14 53.1 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGO60898.1 - 1.3e-12 48.2 0.1 2.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain UCH_1 PF13423.1 EGO60900.1 - 3.4e-80 269.6 0.2 7e-80 268.6 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FLO_LFY PF01698.11 EGO60900.1 - 6.6 5.4 11.6 12 4.6 8.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Porin_3 PF01459.17 EGO60901.1 - 4.2e-77 259.1 0.3 4.9e-77 258.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.13 EGO60902.1 - 2.2e-60 203.4 0.0 3.1e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGO60902.1 - 1.5e-23 83.6 1.2 2.7e-23 82.7 0.8 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EGO60902.1 - 1.8e-06 27.8 0.1 4.1e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGO60902.1 - 0.0093 16.7 0.9 0.098 13.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain TroA PF01297.12 EGO60902.1 - 0.036 13.3 0.0 0.082 12.1 0.0 1.6 1 0 0 1 1 1 0 Periplasmic solute binding protein family KTI12 PF08433.5 EGO60902.1 - 0.038 13.1 0.0 0.078 12.1 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RmlD_sub_bind PF04321.12 EGO60903.1 - 1.7e-50 171.5 0.0 2.3e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EGO60903.1 - 1.1e-22 80.6 0.0 1.4e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGO60903.1 - 7.9e-11 41.3 0.1 3.5e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EGO60903.1 - 1.4e-10 40.3 0.0 1.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EGO60903.1 - 4.5e-08 32.3 0.0 6.7e-05 21.9 0.0 2.5 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGO60903.1 - 0.00041 20.4 0.3 0.00094 19.2 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EGO60903.1 - 0.0028 17.5 1.7 0.013 15.4 1.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EGO60903.1 - 0.007 15.6 0.1 0.095 11.9 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family IGR PF09597.5 EGO60903.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 IGR protein motif PH PF00169.24 EGO60904.1 - 0.019 15.1 0.1 0.053 13.7 0.1 1.7 1 0 0 1 1 1 0 PH domain polyprenyl_synt PF00348.12 EGO60905.1 - 2.7e-71 239.4 0.0 3.4e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF4298 PF14131.1 EGO60905.1 - 0.37 10.6 3.2 0.32 10.8 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) APC8 PF04049.8 EGO60906.1 - 6e-33 113.5 0.1 3.7e-32 111.0 0.0 2.2 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EGO60906.1 - 1.3e-19 68.9 11.6 0.00034 20.1 0.0 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGO60906.1 - 1.4e-17 63.0 13.6 3.1e-06 26.7 0.1 6.9 3 2 4 7 7 7 4 TPR repeat TPR_8 PF13181.1 EGO60906.1 - 4.3e-15 54.2 5.8 0.00025 20.5 0.0 6.3 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EGO60906.1 - 4.9e-14 51.0 21.0 0.17 11.8 0.0 9.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGO60906.1 - 7.2e-10 38.6 12.7 0.024 15.2 0.0 8.2 8 2 1 9 9 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGO60906.1 - 4.4e-07 29.2 6.9 0.099 12.4 0.0 5.5 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGO60906.1 - 4.5e-07 30.3 18.7 1.3e-05 25.6 0.7 7.2 5 2 4 9 9 8 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGO60906.1 - 5.4e-07 29.4 22.9 0.0048 16.8 2.1 6.0 4 1 2 7 7 6 4 Tetratricopeptide repeat TPR_9 PF13371.1 EGO60906.1 - 0.00011 21.9 12.0 2.2 8.1 0.2 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGO60906.1 - 0.00011 22.4 6.8 4.8 7.5 0.1 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGO60906.1 - 0.00019 21.4 10.0 2.5 8.4 0.1 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EGO60906.1 - 0.0033 17.5 12.3 1.2 9.3 0.9 5.9 5 1 2 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.2 EGO60906.1 - 0.0048 16.7 2.6 0.059 13.1 0.1 3.1 2 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_15 PF13429.1 EGO60906.1 - 0.047 12.7 8.1 0.088 11.8 1.8 3.6 2 1 4 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGO60906.1 - 0.068 13.6 20.1 1 9.9 0.1 7.8 10 0 0 10 10 8 0 Tetratricopeptide repeat DUF2424 PF10340.4 EGO60906.1 - 0.11 11.0 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) MIT PF04212.13 EGO60906.1 - 0.51 10.2 0.0 0.51 10.2 0.0 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Vps54 PF07928.7 EGO60908.1 - 3.2e-38 130.8 6.7 5.6e-38 130.1 2.4 3.0 2 1 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 EGO60908.1 - 1.9e-06 26.9 0.6 1.9e-06 26.9 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EGO60908.1 - 0.0058 16.5 2.1 0.18 11.6 0.5 3.2 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.4 EGO60908.1 - 0.027 14.3 0.3 0.078 12.8 0.2 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF904 PF06005.7 EGO60908.1 - 0.029 14.6 2.9 0.38 11.0 2.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Sec8_exocyst PF04048.9 EGO60908.1 - 0.029 14.0 0.5 0.33 10.5 0.1 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain MCM PF00493.18 EGO60909.1 - 1.6e-142 474.2 0.1 2.1e-142 473.8 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGO60909.1 - 1.9e-18 67.0 0.6 5e-18 65.7 0.2 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGO60909.1 - 3.5e-07 29.6 0.0 0.0002 20.6 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGO60909.1 - 8.2e-05 22.3 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGO60909.1 - 0.00085 18.9 0.0 0.0034 16.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EGO60909.1 - 0.0095 16.3 0.6 0.032 14.6 0.4 1.9 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EGO60909.1 - 0.038 13.4 0.1 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Lon_2 PF13337.1 EGO60909.1 - 0.14 10.4 0.3 0.91 7.7 0.0 2.0 2 0 0 2 2 2 0 Putative ATP-dependent Lon protease AMP-binding PF00501.23 EGO60910.1 - 6.9e-16 57.6 0.0 1.2e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme KOW PF00467.24 EGO60910.1 - 0.17 11.6 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 KOW motif 2Fe-2S_thioredx PF01257.14 EGO60911.1 - 2.1e-59 199.2 0.1 2.7e-59 198.9 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Kelch_3 PF13415.1 EGO60912.1 - 1.1e-23 82.7 20.6 1.4e-08 34.6 0.1 8.3 7 2 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EGO60912.1 - 5.1e-22 77.3 12.0 3.9e-07 29.7 0.0 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EGO60912.1 - 5.7e-22 77.2 4.1 3.6e-06 26.8 0.0 7.4 7 0 0 7 7 7 5 Kelch motif Kelch_1 PF01344.20 EGO60912.1 - 2.3e-14 52.6 2.5 8.6e-05 22.0 0.1 5.8 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 EGO60912.1 - 8.6e-14 51.0 7.1 0.00049 20.1 0.0 6.3 6 1 1 7 7 7 3 Kelch motif Kelch_2 PF07646.10 EGO60912.1 - 4.3e-10 38.9 6.0 1.5e-05 24.5 0.4 5.8 5 1 0 5 5 5 1 Kelch motif Ceramidase_alk PF04734.8 EGO60913.1 - 8e-280 929.5 0.0 9.1e-280 929.3 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase PsbX PF06596.6 EGO60913.1 - 1.3 8.7 5.1 2.5 7.8 3.5 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) BCAS2 PF05700.6 EGO60914.1 - 8.7e-36 123.4 0.0 9.9e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.3 EGO60914.1 - 0.0082 15.8 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding cNMP_binding PF00027.24 EGO60915.1 - 1.5e-40 136.8 0.0 3.3e-19 68.5 0.0 2.4 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain GXGXG PF01493.14 EGO60915.1 - 0.049 12.6 0.0 0.26 10.2 0.0 1.9 2 0 0 2 2 2 0 GXGXG motif CDC50 PF03381.10 EGO60916.1 - 2e-93 312.5 0.0 2.4e-93 312.3 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SPT16 PF08644.6 EGO60917.1 - 3.1e-57 192.6 0.1 3.1e-57 192.6 0.1 2.8 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EGO60917.1 - 9.5e-55 184.5 0.3 2.5e-54 183.2 0.2 1.8 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 EGO60917.1 - 1.1e-22 79.8 0.1 3.1e-22 78.3 0.1 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 EGO60917.1 - 2.4e-22 79.5 0.0 4.6e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 GAF_2 PF13185.1 EGO60918.1 - 1.9e-08 34.9 0.0 4.7e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 EGO60918.1 - 0.0047 17.0 0.1 0.0062 16.6 0.1 1.4 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EGO60918.1 - 0.014 15.4 0.0 0.021 14.9 0.0 1.5 1 1 0 1 1 1 0 GAF domain Glyco_hydro_72 PF03198.9 EGO60919.1 - 2.9e-120 400.9 2.5 3.7e-120 400.6 1.7 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EGO60919.1 - 7.4e-07 28.6 0.7 1.1e-05 24.7 0.5 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2713 PF10897.3 EGO60919.1 - 0.01 15.1 0.4 0.021 14.0 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2713) SH3_9 PF14604.1 EGO60920.1 - 5.3e-21 73.9 1.1 2.6e-13 49.3 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain FCH PF00611.18 EGO60920.1 - 6.2e-18 64.7 5.8 1.8e-17 63.2 0.0 3.3 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.17 EGO60920.1 - 1.3e-14 53.5 5.6 2.1e-14 52.9 3.9 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.23 EGO60920.1 - 4.2e-12 45.2 0.0 2.1e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EGO60920.1 - 0.0049 16.3 0.2 0.41 10.1 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 EGO60920.1 - 0.018 15.2 1.0 0.94 9.7 0.1 2.6 2 0 0 2 2 2 0 Bacterial SH3 domain C1_2 PF03107.11 EGO60920.1 - 0.53 10.4 7.8 0.97 9.6 5.4 1.4 1 0 0 1 1 1 0 C1 domain DUF4407 PF14362.1 EGO60920.1 - 2.9 6.7 14.4 5.9 5.7 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) DEAD PF00270.24 EGO60921.1 - 1.1e-33 116.0 0.2 1.7e-32 112.2 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO60921.1 - 1.2e-21 76.3 0.0 2.3e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EGO60921.1 - 0.00027 20.6 0.9 0.015 15.0 0.0 2.9 2 1 1 3 3 3 1 Part of AAA domain Helicase_C_2 PF13307.1 EGO60921.1 - 0.0093 15.9 0.0 0.023 14.6 0.0 1.6 2 0 0 2 2 2 1 Helicase C-terminal domain CMS1 PF14617.1 EGO60921.1 - 0.011 14.8 0.1 0.021 13.8 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 EGO60921.1 - 0.023 14.2 0.0 0.081 12.4 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGO60921.1 - 0.066 13.3 0.7 1.4 9.0 0.4 2.8 2 1 0 2 2 2 0 AAA domain GCS PF03074.11 EGO60925.1 - 5.7e-152 506.0 0.0 9.5e-151 502.0 0.0 2.1 1 1 0 1 1 1 1 Glutamate-cysteine ligase MIG-14_Wnt-bd PF06664.7 EGO60926.1 - 0.21 10.3 3.4 0.2 10.4 0.1 2.2 3 0 0 3 3 3 0 Wnt-binding factor required for Wnt secretion GATA PF00320.22 EGO60929.1 - 1.2e-15 56.5 3.4 2e-15 55.8 2.3 1.4 1 0 0 1 1 1 1 GATA zinc finger Prion_bPrPp PF11587.3 EGO60930.1 - 0.03 13.9 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal Peptidase_C2 PF00648.16 EGO60932.1 - 3.4e-53 180.5 1.1 2.4e-52 177.8 0.8 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease ArfGap PF01412.13 EGO60933.1 - 7.6e-40 135.3 0.2 7.6e-40 135.3 0.1 2.9 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf UBA PF00627.26 EGO60933.1 - 0.17 11.7 1.9 3.4 7.6 0.0 2.5 2 0 0 2 2 2 0 UBA/TS-N domain Cupin_5 PF06172.6 EGO60934.1 - 1.9e-13 50.5 0.0 1.7e-12 47.4 0.0 2.1 1 1 0 1 1 1 1 Cupin superfamily (DUF985) Methyltransf_23 PF13489.1 EGO60935.1 - 1.8e-21 76.5 0.0 2.7e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO60935.1 - 1.2e-09 38.5 0.0 9.7e-09 35.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO60935.1 - 2.4e-08 33.7 0.0 1.9e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO60935.1 - 2.5e-07 31.0 0.0 4.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO60935.1 - 4.5e-07 30.4 0.0 6.8e-06 26.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO60935.1 - 1.2e-05 25.6 0.0 2.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGO60935.1 - 0.00043 19.3 0.0 0.0011 18.0 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EGO60935.1 - 0.0016 17.6 0.0 0.011 14.8 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGO60935.1 - 0.0025 17.2 0.0 0.043 13.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 EGO60935.1 - 0.0059 16.6 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EGO60935.1 - 0.0077 16.2 0.0 0.022 14.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGO60935.1 - 0.026 13.9 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Pyridoxal_deC PF00282.14 EGO60936.1 - 5.4e-20 71.1 0.0 7.1e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EGO60936.1 - 0.00022 20.5 0.0 0.00032 19.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EGO60936.1 - 0.021 13.7 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_5 PF00266.14 EGO60936.1 - 0.048 12.4 0.1 0.13 10.9 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V TRAP_alpha PF03896.11 EGO60937.1 - 3.7e-08 32.7 0.1 7.5e-08 31.7 0.1 1.5 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF2004 PF09406.5 EGO60937.1 - 0.024 14.7 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) HA2 PF04408.18 EGO60940.1 - 1.9e-21 76.0 1.6 4.5e-21 74.7 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGO60940.1 - 2.5e-18 65.9 0.0 6.7e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGO60940.1 - 4.3e-14 52.1 0.0 9.9e-14 50.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO60940.1 - 6.4e-10 38.7 0.1 1.3e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.17 EGO60940.1 - 3.1e-08 33.4 0.2 6.6e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 RWD domain UBA PF00627.26 EGO60940.1 - 2.9e-05 23.7 1.8 0.0074 16.0 0.0 3.8 3 0 0 3 3 3 1 UBA/TS-N domain AAA_22 PF13401.1 EGO60940.1 - 0.00024 21.2 0.1 0.00065 19.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EGO60940.1 - 0.0017 17.3 0.0 0.0035 16.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EGO60940.1 - 0.0035 17.0 0.0 0.025 14.3 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_29 PF13555.1 EGO60940.1 - 0.007 15.8 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EGO60940.1 - 0.0073 15.7 0.0 0.02 14.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EGO60940.1 - 0.0097 15.0 0.1 0.02 14.0 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_23 PF13476.1 EGO60940.1 - 0.032 14.5 1.8 0.072 13.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DND1_DSRM PF14709.1 EGO60940.1 - 0.04 14.1 0.3 0.04 14.1 0.2 2.5 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 PhoH PF02562.11 EGO60940.1 - 0.043 13.0 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Aldo_ket_red PF00248.16 EGO60940.1 - 0.068 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Aldo/keto reductase family PLDc_2 PF13091.1 EGO60942.1 - 5.1e-13 48.8 0.0 1.3e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EGO60942.1 - 6.5e-08 32.1 1.4 0.015 15.0 0.2 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif PNTB PF02233.11 EGO60943.1 - 1.4e-169 564.7 23.8 1.4e-169 564.7 16.5 1.7 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EGO60943.1 - 1.6e-53 180.7 1.3 2.9e-53 179.8 0.9 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EGO60943.1 - 4.5e-51 172.4 0.1 1.1e-50 171.1 0.1 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EGO60943.1 - 8e-32 109.2 2.7 8e-32 109.2 1.9 5.5 6 1 1 7 7 7 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EGO60943.1 - 0.012 14.8 0.2 0.91 8.6 0.0 2.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fumerase PF05681.9 EGO60943.1 - 0.02 13.9 0.1 0.035 13.1 0.1 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Pyr_redox_2 PF07992.9 EGO60943.1 - 0.028 14.3 0.9 0.088 12.6 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lant_dehyd_C PF04738.8 EGO60943.1 - 0.056 11.6 0.0 0.087 11.0 0.0 1.2 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus Methyltransf_31 PF13847.1 EGO60943.1 - 0.085 12.4 0.0 0.9 9.1 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain Shikimate_DH PF01488.15 EGO60943.1 - 0.2 11.7 5.0 5.4 7.1 0.0 4.0 5 0 0 5 5 5 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EGO60944.1 - 1.9e-10 41.0 0.0 2.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGO60944.1 - 4.4e-09 35.9 0.0 6.8e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family GFO_IDH_MocA PF01408.17 EGO60944.1 - 0.00095 19.6 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F-box-like PF12937.2 EGO60946.1 - 3.3e-05 23.5 0.2 0.00011 21.7 0.1 2.1 1 0 0 1 1 1 1 F-box-like Hid1 PF12722.2 EGO60946.1 - 5.5 4.5 11.7 7.9 4.0 8.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein p450 PF00067.17 EGO60947.1 - 6.6e-53 179.8 0.0 5.2e-52 176.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EGO60949.1 - 3.9e-111 371.8 18.3 4.6e-111 371.5 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO60949.1 - 1.6e-21 76.4 27.0 8.9e-15 54.2 3.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 EGO60950.1 - 5e-06 26.2 0.1 6.1e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GFA PF04828.9 EGO60951.1 - 3.1e-18 65.5 1.3 4.4e-18 65.0 0.9 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme FYVE PF01363.16 EGO60951.1 - 1.5 8.7 6.9 1.2 9.0 3.0 2.2 1 1 0 1 1 1 0 FYVE zinc finger Peptidase_C97 PF05903.9 EGO60952.1 - 1.2e-05 25.1 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EGO60952.1 - 0.0019 18.1 0.1 0.042 13.8 0.0 2.3 1 1 0 1 1 1 1 Lecithin retinol acyltransferase DUF2256 PF10013.4 EGO60952.1 - 1.5 8.6 4.3 8.5 6.2 0.5 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) FAD_binding_4 PF01565.18 EGO60953.1 - 9.3e-25 86.7 3.7 1.8e-24 85.8 2.1 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EGO60953.1 - 0.13 12.2 0.8 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 Berberine and berberine like Fungal_trans PF04082.13 EGO60954.1 - 1.4e-50 171.6 0.2 2.3e-50 170.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EGO60954.1 - 8.2e-08 32.0 8.2 2.4e-05 24.3 0.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO60954.1 - 6.5e-06 26.1 15.4 0.00023 21.3 0.9 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGO60954.1 - 0.66 10.3 9.8 0.095 13.0 0.3 3.4 3 0 0 3 3 3 0 Zinc-finger double domain Ank_2 PF12796.2 EGO60955.1 - 1.6e-23 82.8 2.2 3.8e-14 52.7 0.3 2.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGO60955.1 - 1.1e-17 62.8 1.1 4.2e-08 32.6 0.4 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EGO60955.1 - 1.7e-15 57.0 4.3 3.5e-08 33.7 0.2 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO60955.1 - 1.5e-14 53.6 0.9 5.1e-08 32.9 0.4 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO60955.1 - 4e-10 38.9 0.2 0.00067 19.6 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat TP6A_N PF04406.9 EGO60956.1 - 3.8e-20 71.3 0.2 1.3e-19 69.6 0.0 2.0 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF1707 PF08044.6 EGO60956.1 - 0.072 12.8 0.6 0.17 11.6 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Prenyltrans PF00432.16 EGO60957.1 - 1.2e-28 98.3 2.9 8.6e-09 34.8 0.1 4.7 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGO60957.1 - 5.9e-25 87.8 1.2 1.5e-16 60.8 0.1 4.8 4 2 0 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGO60957.1 - 2.2e-22 79.1 0.1 5.2e-12 45.7 0.2 5.8 4 2 1 5 5 5 2 Prenyltransferase-like Pec_lyase PF09492.5 EGO60957.1 - 1.7e-08 33.9 0.2 0.0061 15.7 0.0 4.3 2 1 2 4 4 4 3 Pectic acid lyase A2M_comp PF07678.9 EGO60957.1 - 1.4e-05 24.5 0.0 0.013 14.7 0.0 3.2 3 1 1 4 4 4 2 A-macroglobulin complement component SGS PF05002.10 EGO60958.1 - 7.2e-26 89.7 0.1 2.3e-25 88.1 0.1 1.9 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EGO60958.1 - 2.9e-17 63.0 0.0 5.1e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EGO60958.1 - 1.5e-06 27.7 7.5 3.3e-05 23.4 2.4 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGO60958.1 - 6.2e-05 22.6 6.4 0.085 12.8 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGO60958.1 - 0.00044 19.7 4.4 0.055 13.1 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGO60958.1 - 0.0028 18.3 10.4 0.23 12.1 3.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGO60958.1 - 0.0057 16.9 3.3 0.43 10.9 0.4 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGO60958.1 - 0.039 13.8 3.6 9.9 6.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGO60958.1 - 0.093 12.5 1.7 6.7 6.7 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGO60958.1 - 0.64 10.8 3.1 32 5.5 0.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Glyco_transf_21 PF13506.1 EGO60959.1 - 4.7e-12 45.5 0.1 4.6e-05 22.7 0.0 3.5 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EGO60959.1 - 2.8e-10 40.3 0.0 5.9e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGO60959.1 - 0.006 16.2 0.0 0.018 14.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 tRNA_int_endo PF01974.12 EGO60960.1 - 1.8e-19 69.3 0.0 4.6e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EGO60960.1 - 4.4e-06 26.1 0.0 0.027 14.0 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Methyltransf_PK PF05891.7 EGO60961.1 - 2.6e-90 301.5 0.0 3e-90 301.3 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EGO60961.1 - 2.6e-05 23.9 0.0 4.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO60961.1 - 0.0092 16.4 0.0 0.016 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO60961.1 - 0.0096 16.4 0.1 0.03 14.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO60961.1 - 0.018 15.4 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EGO60961.1 - 0.036 13.2 0.0 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_11 PF08241.7 EGO60961.1 - 0.039 14.4 0.0 0.077 13.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 EGO60962.1 - 1.3e-07 31.0 0.0 3.9e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGO60962.1 - 0.017 14.8 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family PEGSRP PF07623.6 EGO60962.1 - 0.069 12.4 2.7 0.14 11.4 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) Pkinase_Tyr PF07714.12 EGO60962.1 - 0.13 11.2 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase PBP PF01161.15 EGO60963.1 - 6.9e-29 100.5 0.0 9.8e-29 100.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Erythro_esteras PF05139.9 EGO60964.1 - 8.3e-141 469.1 3.1 9.6e-141 468.9 2.2 1.0 1 0 0 1 1 1 1 Erythromycin esterase Con-6 PF10346.4 EGO60965.1 - 3e-31 106.5 1.8 3e-15 55.3 0.0 2.6 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 EGO60965.1 - 0.00098 18.6 5.0 0.0015 18.0 1.3 2.0 1 1 1 2 2 2 1 SpoIIIAH-like protein SMP PF04927.7 EGO60966.1 - 8.6e-21 73.6 6.0 2.2e-17 62.7 0.4 2.1 2 0 0 2 2 2 2 Seed maturation protein Mito_fiss_reg PF05308.6 EGO60966.1 - 0.016 14.5 2.7 0.017 14.4 1.9 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator IF-2 PF11987.3 EGO60966.1 - 0.068 13.0 0.4 0.098 12.5 0.3 1.4 1 1 0 1 1 1 0 Translation-initiation factor 2 Ifi-6-16 PF06140.8 EGO60966.1 - 0.12 12.2 0.1 11 5.9 0.0 2.1 2 0 0 2 2 2 0 Interferon-induced 6-16 family adh_short PF00106.20 EGO60967.1 - 2.9e-16 59.8 0.0 4.4e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO60967.1 - 3e-10 40.2 0.0 4.4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO60967.1 - 3.3e-10 39.9 0.1 5.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO60967.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EGO60967.1 - 0.018 14.7 0.1 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EGO60967.1 - 0.053 12.4 0.1 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.14 EGO60967.1 - 0.1 11.7 0.1 0.25 10.4 0.1 1.6 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 EGO60968.1 - 7.8e-25 87.8 0.2 8.1e-24 84.4 0.2 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGO60968.1 - 1.2e-06 28.4 0.0 2.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGO60968.1 - 0.0083 16.2 0.0 0.045 13.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGO60968.1 - 0.011 14.7 0.4 0.018 14.1 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 EGO60968.1 - 0.12 11.2 1.3 0.19 10.6 0.9 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO60968.1 - 0.17 10.6 0.1 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DEAD PF00270.24 EGO60970.1 - 5.3e-40 136.6 0.0 8.7e-40 135.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGO60970.1 - 5.9e-22 77.3 0.0 5.3e-21 74.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGO60970.1 - 0.00025 20.9 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EGO60970.1 - 0.016 14.9 0.0 0.063 13.0 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 EGO60970.1 - 0.03 13.9 0.0 0.079 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.16 EGO60970.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Pro_CA PF00484.14 EGO60971.1 - 8.9e-13 48.5 0.0 1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase 60KD_IMP PF02096.15 EGO60972.1 - 4.2e-31 108.1 4.7 6.6e-31 107.5 3.2 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein TOM13 PF08219.6 EGO60973.1 - 3.2e-32 110.1 0.0 3.9e-32 109.8 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.8 EGO60974.1 - 1.1e-25 89.7 0.0 2e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.1 EGO60974.1 - 6.7e-13 47.9 0.9 1.1e-12 47.2 0.6 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EGO60974.1 - 1.8e-09 37.5 0.0 3.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 UBX domain Gtr1_RagA PF04670.7 EGO60975.1 - 5.4e-96 320.2 0.0 7.2e-96 319.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EGO60975.1 - 4.1e-09 35.9 0.1 6.2e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGO60975.1 - 2.5e-08 33.4 0.0 4.5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EGO60975.1 - 4.2e-06 26.7 0.0 7.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGO60975.1 - 4.6e-05 23.8 0.0 8.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 EGO60975.1 - 0.0012 18.3 0.4 0.0094 15.4 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGO60975.1 - 0.0041 16.3 0.0 0.0072 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DUF815 PF05673.8 EGO60975.1 - 0.0069 15.3 0.1 0.016 14.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 EGO60975.1 - 0.0097 16.2 0.1 0.019 15.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter G-alpha PF00503.15 EGO60975.1 - 0.018 13.7 0.3 0.3 9.7 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Sigma54_activat PF00158.21 EGO60975.1 - 0.048 13.1 0.1 0.079 12.4 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Ank_2 PF12796.2 EGO60976.1 - 2e-53 178.7 16.3 8.4e-14 51.6 0.1 11.8 6 5 3 9 9 9 7 Ankyrin repeats (3 copies) Ank PF00023.25 EGO60976.1 - 7e-32 107.6 35.6 2.7e-05 23.7 0.0 17.0 18 2 2 20 20 20 7 Ankyrin repeat Ank_3 PF13606.1 EGO60976.1 - 2.5e-26 89.0 20.1 0.00016 21.5 0.0 15.3 19 1 1 20 20 20 4 Ankyrin repeat Ank_5 PF13857.1 EGO60976.1 - 1.3e-20 72.8 15.2 2.5e-07 30.7 0.0 9.9 8 2 3 11 11 11 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGO60976.1 - 1.2e-18 67.0 19.5 1.2e-08 35.2 0.0 10.9 9 2 3 12 12 12 5 Ankyrin repeats (many copies) Zn_clus PF00172.13 EGO60977.1 - 1.1e-07 31.6 11.0 2.5e-07 30.5 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF937 PF06078.6 EGO60977.1 - 0.071 13.3 0.1 0.39 10.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) MFS_1 PF07690.11 EGO60979.1 - 2.9e-44 151.2 53.4 4.9e-43 147.1 37.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO60979.1 - 7.9e-13 47.7 33.5 1.2e-11 43.8 13.5 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter FAD_binding_4 PF01565.18 EGO60980.1 - 7.7e-16 57.8 0.5 1.4e-15 56.9 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGO60980.1 - 8.7e-12 44.7 0.1 2.1e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like ComC PF03047.9 EGO60981.1 - 0.069 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 COMC family Metallophos_2 PF12850.2 EGO60982.1 - 1.1e-10 41.6 0.1 1.9e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGO60982.1 - 8.2e-09 35.1 0.6 5e-08 32.5 0.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase CPL PF08144.6 EGO60982.1 - 0.077 12.8 0.2 0.15 11.9 0.0 1.5 2 0 0 2 2 2 0 CPL (NUC119) domain adh_short PF00106.20 EGO60983.1 - 5.3e-30 104.5 0.3 1.1e-29 103.4 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO60983.1 - 3.9e-21 75.9 0.1 5.2e-21 75.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO60983.1 - 4.6e-13 49.2 0.2 8.6e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO60983.1 - 0.00024 20.5 0.0 0.00059 19.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SR-25 PF10500.4 EGO60983.1 - 0.17 11.2 5.1 0.25 10.7 3.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ank_2 PF12796.2 EGO60984.1 - 5.8e-19 68.2 0.1 2.4e-09 37.3 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGO60984.1 - 4.1e-13 48.4 2.1 9.4e-05 22.0 0.0 5.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 EGO60984.1 - 3.6e-12 45.2 1.3 0.00067 19.6 0.0 6.2 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.1 EGO60984.1 - 4e-07 30.3 0.1 0.0031 17.9 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGO60984.1 - 0.00015 21.8 1.0 0.017 15.3 0.0 4.4 5 0 0 5 5 5 1 Ankyrin repeats (many copies) F-box-like_2 PF13013.1 EGO60984.1 - 0.00053 19.6 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.28 EGO60984.1 - 0.026 14.1 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 F-box domain Ank PF00023.25 EGO60985.1 - 2.1e-09 36.7 0.3 0.002 17.8 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGO60985.1 - 5e-09 36.4 0.4 3.1e-05 24.3 0.0 3.4 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGO60985.1 - 2.9e-08 33.9 0.1 5.4e-07 29.8 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGO60985.1 - 5.6e-07 29.6 0.6 7.9e-06 25.9 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO60985.1 - 1.6e-06 27.8 0.2 0.065 13.5 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat S_100 PF01023.14 EGO60985.1 - 0.14 11.4 0.0 0.38 10.0 0.0 1.7 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain NAD_binding_8 PF13450.1 EGO60986.1 - 5.6e-08 32.6 0.0 1.9e-07 30.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO60986.1 - 1.1e-05 24.5 0.0 0.0039 16.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EGO60986.1 - 5.5e-05 22.4 0.0 0.003 16.6 0.0 3.1 3 1 0 3 3 3 1 Flavin containing amine oxidoreductase DUF2628 PF10947.3 EGO60986.1 - 0.00089 19.0 0.4 0.00089 19.0 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2628) Pyr_redox_2 PF07992.9 EGO60986.1 - 0.04 13.7 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3860 PF12976.2 EGO60986.1 - 0.066 13.0 0.1 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) Pyr_redox PF00070.22 EGO60986.1 - 0.17 12.3 0.0 1.8 9.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RRM_6 PF14259.1 EGO60988.1 - 0.033 14.1 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4128 PF13554.1 EGO60989.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function p450 PF00067.17 EGO60990.1 - 2.1e-93 313.3 0.0 2.7e-93 313.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ParA PF10609.4 EGO60992.1 - 6.8e-36 122.0 0.1 1.2e-35 121.1 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGO60992.1 - 3.3e-14 52.7 0.0 6.6e-14 51.7 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EGO60992.1 - 9.1e-07 28.2 0.0 2.9e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 EGO60992.1 - 1.4e-05 24.2 0.2 2.8e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.1 EGO60992.1 - 2.7e-05 24.1 0.0 7.7e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EGO60992.1 - 0.0012 17.6 0.5 0.0018 17.0 0.3 1.2 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 EGO60992.1 - 0.0031 16.9 0.1 0.0057 16.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 EGO60992.1 - 0.014 14.7 0.5 0.022 14.1 0.3 1.5 1 1 0 1 1 1 0 YhjQ protein AAA_26 PF13500.1 EGO60992.1 - 0.015 14.9 0.1 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGO60992.1 - 0.058 12.5 1.1 0.12 11.5 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 EGO60992.1 - 0.064 12.9 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase SAM_decarbox PF01536.11 EGO60993.1 - 2.9e-85 285.8 0.0 4.3e-84 282.0 0.0 2.2 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase PAT1 PF09770.4 EGO60994.1 - 2.7 6.1 37.0 3.7 5.6 25.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F-box-like PF12937.2 EGO60995.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.2 EGO60995.1 - 4.5 7.0 5.9 5.6 6.6 0.0 3.5 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Pex14_N PF04695.8 EGO60996.1 - 2 8.4 4.2 3.5 7.6 2.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region 2-Hacid_dh_C PF02826.14 EGO60998.1 - 7.7e-39 132.6 0.0 1.3e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EGO60998.1 - 1.1e-07 31.8 0.0 1.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGO60998.1 - 0.033 14.6 0.2 0.09 13.2 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Striatin PF08232.7 EGO60999.1 - 0.29 11.4 3.8 0.19 12.0 1.1 1.8 1 1 0 2 2 2 0 Striatin family Pneumo_att_G PF05539.6 EGO60999.1 - 2.5 7.3 9.3 3.6 6.8 6.4 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G bZIP_1 PF00170.16 EGO61002.1 - 0.00015 21.6 8.8 0.00015 21.6 6.1 2.4 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 EGO61002.1 - 7 6.5 15.8 0.39 10.5 6.5 2.3 3 0 0 3 3 3 0 Basic region leucine zipper Aldolase_II PF00596.16 EGO61004.1 - 2.3e-44 151.2 0.2 3e-44 150.8 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain 2OG-Fe_Oxy_2 PF10014.4 EGO61005.1 - 5.2e-46 156.5 0.3 6.9e-46 156.1 0.2 1.2 1 0 0 1 1 1 1 2OG-Fe dioxygenase Pept_tRNA_hydro PF01195.14 EGO61006.1 - 2.1e-27 95.8 0.0 2.7e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase BAR PF03114.13 EGO61007.1 - 3.3e-65 219.8 3.2 4.2e-65 219.4 2.2 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.10 EGO61007.1 - 0.061 13.7 0.2 0.45 10.9 0.0 2.5 3 0 0 3 3 3 0 CP12 domain BAR PF03114.13 EGO61008.1 - 2.4e-59 200.6 4.3 3.1e-59 200.2 3.0 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EGO61008.1 - 9.6e-07 28.0 1.3 1.4e-06 27.4 0.9 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking IMD PF08397.6 EGO61008.1 - 0.01 15.1 0.6 0.01 15.1 0.4 1.5 2 0 0 2 2 2 0 IRSp53/MIM homology domain IncA PF04156.9 EGO61008.1 - 0.29 10.7 5.2 0.62 9.6 3.6 1.5 1 0 0 1 1 1 0 IncA protein DUF883 PF05957.8 EGO61008.1 - 3.1 8.2 6.3 12 6.3 4.3 2.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF2580 PF10824.3 EGO61008.1 - 3.7 7.9 6.7 24 5.3 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2580) APG6 PF04111.7 EGO61008.1 - 6.7 5.6 10.2 2.2 7.2 5.2 1.4 2 0 0 2 2 2 0 Autophagy protein Apg6 Cyclin_N PF00134.18 EGO61009.1 - 1.8e-05 24.2 0.0 7.1e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Amino_oxidase PF01593.19 EGO61010.1 - 1.7e-75 254.8 0.1 2.1e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGO61010.1 - 2e-09 37.3 0.0 5.3e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGO61010.1 - 0.00015 20.8 0.1 0.00039 19.4 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO61010.1 - 0.0031 17.6 0.0 0.015 15.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGO61010.1 - 0.0075 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EGO61010.1 - 0.031 13.3 0.3 0.06 12.3 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EGO61010.1 - 0.032 13.3 0.1 0.052 12.6 0.1 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EGO61010.1 - 0.064 11.7 0.4 0.1 11.0 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EGO61010.1 - 0.18 12.2 0.2 0.49 10.8 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO61010.1 - 0.5 10.1 2.5 0.34 10.6 0.1 1.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Ammonium_transp PF00909.16 EGO61011.1 - 1.5e-120 402.3 27.5 1.8e-120 402.1 19.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Con-6 PF10346.4 EGO61012.1 - 6.8e-18 63.7 0.3 1.5e-17 62.7 0.1 1.7 2 0 0 2 2 2 1 Conidiation protein 6 DUF1996 PF09362.5 EGO61015.1 - 1.6e-92 309.4 0.5 1.9e-92 309.1 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DLH PF01738.13 EGO61016.1 - 8e-18 64.5 0.1 4.7e-17 61.9 0.1 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGO61016.1 - 0.00041 20.1 0.0 0.00065 19.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGO61016.1 - 0.017 14.3 0.3 0.15 11.2 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family RelB_N PF12910.2 EGO61016.1 - 0.079 12.3 0.1 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin stability system N-terminal EmrE PF13536.1 EGO61016.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Multidrug resistance efflux transporter Glyco_hydro_47 PF01532.15 EGO61018.1 - 2.3e-151 504.4 0.0 1.6e-149 498.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.8 EGO61018.1 - 0.064 12.2 0.0 0.21 10.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 F-box-like PF12937.2 EGO61019.1 - 0.00026 20.6 0.1 0.00059 19.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like APOBEC_C PF05240.9 EGO61019.1 - 0.021 14.2 0.0 0.33 10.3 0.0 2.3 2 0 0 2 2 2 0 APOBEC-like C-terminal domain TauD PF02668.11 EGO61020.1 - 6e-27 94.9 0.1 1.2e-26 93.9 0.0 1.5 1 1 1 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family LssY_C PF14067.1 EGO61020.1 - 0.056 12.4 0.1 1.5 7.8 0.0 2.2 2 0 0 2 2 2 0 LssY C-terminus DUF3328 PF11807.3 EGO61021.1 - 4.2e-11 42.9 0.5 4.4e-11 42.8 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EGO61022.1 - 1.5e-06 28.0 0.0 1.5e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NatB_MDM20 PF09797.4 EGO61022.1 - 0.074 11.7 0.0 0.081 11.6 0.0 1.0 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit GFA PF04828.9 EGO61023.1 - 2.9e-08 33.5 0.0 2.9e-08 33.5 0.0 2.4 4 0 0 4 4 4 1 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.1 EGO61023.1 - 0.1 12.1 0.2 0.1 12.1 0.1 2.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EGO61023.1 - 0.13 11.5 0.1 0.13 11.5 0.1 3.0 3 1 0 3 3 3 0 zinc-ribbon domain Plant_zn_clust PF10533.4 EGO61023.1 - 0.43 10.2 2.6 10 5.8 0.2 2.6 2 0 0 2 2 2 0 Plant zinc cluster domain Chromate_transp PF02417.10 EGO61024.1 - 3.4e-51 173.2 28.0 1.2e-27 96.5 9.7 2.4 2 0 0 2 2 2 2 Chromate transporter BaxI_1 PF12811.2 EGO61024.1 - 0.012 14.7 1.0 0.012 14.7 0.7 2.0 2 1 1 3 3 3 0 Bax inhibitor 1 like TFIIA_gamma_N PF02268.11 EGO61025.1 - 8.5e-10 38.0 0.4 0.00011 21.7 0.1 2.3 2 0 0 2 2 2 2 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EGO61025.1 - 2e-08 33.8 0.1 7.5e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Transcription initiation factor IIA, gamma subunit ATS PF15445.1 EGO61026.1 - 0.24 10.4 0.6 0.41 9.7 0.4 1.3 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 DUF3328 PF11807.3 EGO61028.1 - 7e-59 199.1 3.6 8.5e-59 198.8 2.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_61 PF03443.9 EGO61029.1 - 9.2e-63 211.9 0.1 1.1e-62 211.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fasciclin PF02469.17 EGO61030.1 - 2.9e-31 108.1 0.0 2.3e-17 63.1 0.4 3.4 2 2 0 2 2 2 2 Fasciclin domain Exo_endo_phos PF03372.18 EGO61032.1 - 1.8e-13 51.0 7.9 3.2e-13 50.1 5.5 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EGO61032.1 - 0.00072 19.1 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain DUF4232 PF14016.1 EGO61032.1 - 0.068 12.8 0.0 0.45 10.1 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4232) Swi5 PF07061.6 EGO61033.1 - 1.9e-27 94.8 0.2 4.8e-27 93.5 0.1 1.7 1 0 0 1 1 1 1 Swi5 DCP1 PF06058.8 EGO61033.1 - 1.3e-09 38.1 0.0 2.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Dcp1-like decapping family Use1 PF09753.4 EGO61033.1 - 0.0028 17.1 0.5 0.01 15.3 0.2 1.8 2 0 0 2 2 2 1 Membrane fusion protein Use1 Ribonuclease PF00545.15 EGO61034.1 - 2e-18 66.2 0.2 2.8e-18 65.7 0.2 1.2 1 0 0 1 1 1 1 ribonuclease Herpes_UL45 PF05473.7 EGO61034.1 - 0.1 12.0 0.2 0.13 11.6 0.2 1.1 1 0 0 1 1 1 0 UL45 protein DUF3433 PF11915.3 EGO61035.1 - 9.8e-47 157.0 9.3 8.6e-26 89.9 1.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Ras PF00071.17 EGO61037.1 - 9.9e-16 57.5 0.1 3e-07 29.9 0.0 2.9 2 1 0 2 2 2 2 Ras family Miro PF08477.8 EGO61037.1 - 1.4e-08 35.2 0.0 7.5e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein G-alpha PF00503.15 EGO61037.1 - 1.3e-05 24.1 0.2 1.9e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 G-protein alpha subunit NACHT PF05729.7 EGO61037.1 - 2.9e-05 23.8 0.0 4.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Arf PF00025.16 EGO61037.1 - 0.00073 18.8 0.0 0.0031 16.7 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_24 PF13479.1 EGO61037.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGO61037.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGO61037.1 - 0.002 18.2 0.0 0.0049 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EGO61037.1 - 0.0044 16.7 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EGO61037.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.13 EGO61037.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 EGO61037.1 - 0.014 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGO61037.1 - 0.043 14.6 0.0 0.14 12.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain PduV-EutP PF10662.4 EGO61037.1 - 0.053 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EGO61037.1 - 0.058 13.6 0.2 0.22 11.8 0.0 2.0 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 EGO61037.1 - 0.072 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EGO61037.1 - 0.075 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 EGO61037.1 - 0.078 12.6 0.2 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 NTPase Septin PF00735.13 EGO61037.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Septin Peptidase_M48 PF01435.13 EGO61038.1 - 1.3e-51 175.3 0.0 2.1e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF2613 PF11021.3 EGO61038.1 - 0.4 10.4 4.2 0.95 9.2 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF3149 PF11346.3 EGO61038.1 - 7.7 6.1 6.4 0.49 9.9 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) Beta-lactamase PF00144.19 EGO61040.1 - 5.8e-39 134.0 0.1 8.9e-39 133.4 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.1 EGO61040.1 - 0.088 12.2 0.0 0.87 8.9 0.0 2.1 2 0 0 2 2 2 0 Beta-lactamase enzyme family TRP PF06011.7 EGO61041.1 - 8.3e-146 485.9 27.5 1.1e-145 485.6 19.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EGO61041.1 - 2.3e-39 134.6 0.3 4e-39 133.8 0.2 1.4 1 0 0 1 1 1 1 ML-like domain 5TM-5TMR_LYT PF07694.7 EGO61041.1 - 0.0029 16.9 8.5 0.0029 16.9 5.9 2.5 3 0 0 3 3 3 1 5TMR of 5TMR-LYT E1_DerP2_DerF2 PF02221.10 EGO61041.1 - 0.012 15.8 0.1 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 ML domain RAP1 PF07218.6 EGO61044.1 - 4.8 5.1 8.4 5.8 4.8 0.4 2.0 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) WPP PF13943.1 EGO61050.1 - 3.1 8.0 12.1 1.2 9.3 4.3 2.6 2 0 0 2 2 2 0 WPP domain Ribosomal_L17 PF01196.14 EGO61051.1 - 1.1e-29 102.8 0.0 1.9e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 Mn_catalase PF05067.7 EGO61051.1 - 0.005 15.6 0.0 0.0078 15.0 0.0 1.3 1 0 0 1 1 1 1 Manganese containing catalase DUF1253 PF06862.7 EGO61052.1 - 5.2e-167 555.7 0.3 7.1e-167 555.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) JAB PF01398.16 EGO61053.1 - 1.1e-15 57.3 0.0 1.8e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EGO61053.1 - 1.9e-14 53.7 0.1 3.1e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function SUZ PF12752.2 EGO61054.1 - 9.6e-16 58.0 4.9 9.6e-16 58.0 3.4 3.0 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 EGO61054.1 - 9.8e-08 31.5 0.0 2.3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-CCHC_3 PF13917.1 EGO61055.1 - 5.6e-10 38.7 0.1 1.3e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle cwf18 PF08315.7 EGO61056.1 - 6e-46 156.0 6.1 6e-46 156.0 4.2 2.1 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor PPR_2 PF13041.1 EGO61057.1 - 1.8e-19 69.4 0.0 1.7e-09 37.5 0.0 4.6 4 1 1 5 5 5 3 PPR repeat family PPR_1 PF12854.2 EGO61057.1 - 3e-14 52.1 0.0 1.8e-06 27.3 0.0 4.4 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 EGO61057.1 - 3.2e-11 42.5 1.7 0.00016 21.6 0.0 5.7 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.15 EGO61057.1 - 7.9e-09 34.9 0.4 0.0058 16.5 0.0 5.0 4 1 0 4 4 4 2 PPR repeat Acyl_transf_3 PF01757.17 EGO61058.1 - 2.3e-37 128.6 28.4 3.8e-27 95.0 9.5 2.6 2 1 0 2 2 2 2 Acyltransferase family DUF1600 PF07667.6 EGO61058.1 - 0.04 14.0 2.7 0.12 12.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1600) ALAD PF00490.16 EGO61059.1 - 4.7e-118 393.7 0.0 5.9e-118 393.4 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Y_phosphatase3 PF13350.1 EGO61062.1 - 3.3e-33 115.2 0.0 4.6e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGO61062.1 - 2e-06 27.8 0.0 7.2e-06 26.0 0.0 2.0 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EGO61062.1 - 0.0028 17.0 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EGO61062.1 - 0.0034 16.7 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EGO61062.1 - 0.13 11.8 0.0 0.36 10.3 0.0 1.6 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EGO61062.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF3141 PF11339.3 EGO61063.1 - 0.26 9.5 2.6 0.39 8.9 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Ribosomal_S4 PF00163.14 EGO61064.1 - 9.7e-13 48.3 3.7 1e-12 48.2 2.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EGO61064.1 - 2.3e-11 42.9 0.0 8.5e-11 41.1 0.0 1.9 2 0 0 2 2 2 1 S4 domain Herpes_LAMP2 PF06126.6 EGO61064.1 - 0.041 12.2 0.2 0.047 12.0 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Ribosomal_S18 PF01084.15 EGO61065.1 - 3.6e-10 39.5 0.0 1.2e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 Ribosomal protein S18 PPR_3 PF13812.1 EGO61066.1 - 2.2e-06 27.4 4.1 0.035 14.3 0.0 4.5 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EGO61066.1 - 0.0004 20.3 0.6 34 4.5 0.0 5.5 5 1 1 6 6 6 2 PPR repeat family PPR PF01535.15 EGO61066.1 - 0.038 13.9 6.7 0.96 9.5 0.0 5.0 5 0 0 5 5 5 0 PPR repeat FTA4 PF13093.1 EGO61067.1 - 2.9e-64 216.3 0.0 3.4e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ERCC4 PF02732.10 EGO61067.1 - 0.04 13.6 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 ERCC4 domain PEARLI-4 PF05278.7 EGO61067.1 - 0.71 9.1 3.9 0.2 10.9 0.1 1.8 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) PS_Dcarbxylase PF02666.10 EGO61068.1 - 5.2e-54 182.6 0.0 7.6e-54 182.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EGO61068.1 - 1.6e-38 130.3 0.1 2.4e-21 75.3 0.0 3.0 3 0 0 3 3 3 2 C2 domain EF-hand_7 PF13499.1 EGO61068.1 - 0.0011 19.0 0.7 0.0047 17.0 0.2 2.3 3 0 0 3 3 3 1 EF-hand domain pair CEP76-C2 PF15627.1 EGO61068.1 - 0.0028 17.1 0.0 2.7 7.4 0.0 2.4 2 0 0 2 2 2 2 CEP76 C2 domain EF-hand_6 PF13405.1 EGO61068.1 - 0.009 15.8 0.0 0.032 14.1 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 EGO61068.1 - 0.026 13.8 0.0 0.063 12.6 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.1 EGO61068.1 - 0.042 13.2 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 EF hand Coatomer_E PF04733.9 EGO61070.1 - 4e-57 193.6 6.0 4.6e-57 193.4 4.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EGO61070.1 - 4.9e-07 29.9 27.1 0.00076 19.7 3.4 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EGO61070.1 - 6.2e-05 23.0 1.9 0.17 12.0 0.0 3.5 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EGO61070.1 - 0.0005 19.5 2.0 0.34 10.6 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Type_III_YscG PF09477.5 EGO61070.1 - 0.00092 19.2 7.8 0.1 12.7 0.2 4.1 1 1 3 4 4 4 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_16 PF13432.1 EGO61070.1 - 0.0014 19.2 2.4 0.0014 19.2 1.7 5.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGO61070.1 - 0.0043 16.7 0.1 0.34 10.7 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGO61070.1 - 0.0044 17.5 0.5 0.0044 17.5 0.4 6.0 4 3 2 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 EGO61070.1 - 0.0061 16.8 23.5 0.13 12.7 0.3 5.7 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGO61070.1 - 0.011 15.5 0.0 0.011 15.5 0.0 6.4 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGO61070.1 - 0.034 13.9 10.2 10 6.2 0.0 6.0 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGO61070.1 - 0.067 13.1 12.8 1.9 8.4 0.1 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGO61070.1 - 0.11 12.9 15.9 0.97 10.0 0.0 5.5 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGO61070.1 - 0.67 9.6 14.8 0.23 11.1 0.2 5.2 4 2 1 5 5 5 0 TPR repeat TPR_9 PF13371.1 EGO61070.1 - 2.1 8.2 7.6 0.99 9.3 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGO61070.1 - 9.4 6.3 11.7 14 5.8 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2462 PF09495.5 EGO61071.1 - 6.4e-08 33.2 11.9 8.8e-08 32.7 8.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Peptidase_S30 PF01577.11 EGO61071.1 - 0.065 12.6 3.5 0.072 12.4 2.4 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease PepX_C PF08530.5 EGO61072.1 - 1.6e-43 149.1 0.0 3.1e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 EGO61072.1 - 2.1e-38 132.2 0.3 3.4e-38 131.6 0.2 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EGO61072.1 - 2.6e-06 27.4 0.0 4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO61072.1 - 1.2e-05 25.1 0.0 3e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGO61072.1 - 0.0073 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Med5 PF08689.5 EGO61075.1 - 6.3e-299 994.0 0.0 8.3e-299 993.6 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 FMN_dh PF01070.13 EGO61076.1 - 1.4e-113 379.3 0.0 1.8e-113 379.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EGO61076.1 - 0.00028 20.1 1.4 0.00049 19.3 0.5 1.7 2 0 0 2 2 2 1 Nitronate monooxygenase Glu_synthase PF01645.12 EGO61076.1 - 0.00052 19.0 0.4 0.0011 17.9 0.1 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 EGO61076.1 - 0.0018 17.2 0.3 0.015 14.2 0.1 2.3 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 EGO61076.1 - 0.0045 16.0 0.6 0.97 8.4 0.1 2.5 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 EGO61076.1 - 0.014 14.3 0.4 0.46 9.4 0.0 2.3 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF4202 PF13875.1 EGO61077.1 - 3.1e-43 147.5 0.1 3.4e-43 147.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Peptidase_M16 PF00675.15 EGO61077.1 - 0.00091 19.0 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) GatB_Yqey PF02637.13 EGO61077.1 - 0.056 13.1 0.0 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 GatB domain 14-3-3 PF00244.15 EGO61081.1 - 2.4e-10 39.8 0.0 2.7e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 14-3-3 protein Kin17_mid PF10357.4 EGO61082.1 - 4.2e-46 155.7 1.3 1.2e-45 154.2 0.9 1.8 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EGO61082.1 - 1e-05 25.5 5.0 1.9e-05 24.7 3.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGO61082.1 - 0.0005 20.1 4.0 0.0011 19.0 2.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGO61082.1 - 0.74 9.9 5.2 0.33 11.0 0.8 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Selenoprotein_S PF06936.6 EGO61082.1 - 1.2 8.6 11.6 0.067 12.7 3.9 1.9 2 0 0 2 2 2 0 Selenoprotein S (SelS) Spt4 PF06093.8 EGO61083.1 - 9.5e-33 111.9 0.2 1.1e-32 111.6 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RNHCP PF12647.2 EGO61083.1 - 0.081 12.7 0.2 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 RNHCP domain AMPKBI PF04739.10 EGO61084.1 - 1.4e-29 101.9 0.9 1.4e-29 101.9 0.6 2.2 3 0 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interation domain Glyco_hydro_65N PF03636.10 EGO61084.1 - 0.13 11.5 0.0 5.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, N-terminal domain Peptidase_M22 PF00814.20 EGO61085.1 - 2.4e-82 276.4 0.0 2.8e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family EPL1 PF10513.4 EGO61087.1 - 1.3e-27 97.0 3.4 1.3e-27 97.0 2.4 3.4 2 1 1 4 4 4 1 Enhancer of polycomb-like EF-hand_1 PF00036.27 EGO61088.1 - 2.2e-26 89.0 12.7 4.9e-07 28.5 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGO61088.1 - 2e-23 82.3 3.3 1.2e-12 47.7 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGO61088.1 - 2.4e-20 70.5 5.2 4.7e-05 22.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGO61088.1 - 8.4e-19 66.0 12.2 2.2e-06 26.7 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EGO61088.1 - 5.3e-15 54.7 13.2 2.4e-05 23.8 0.8 4.5 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGO61088.1 - 2.3e-07 30.8 0.0 0.00028 20.8 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EGO61088.1 - 3.4e-06 26.7 8.5 0.002 17.8 0.4 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EGO61088.1 - 0.07 13.0 0.1 1.7 8.5 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain Squash PF00299.13 EGO61089.1 - 0.061 13.1 0.2 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Squash family serine protease inhibitor Ribosomal_S9 PF00380.14 EGO61095.1 - 2.6e-37 127.7 0.8 5.5e-37 126.7 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.14 EGO61096.1 - 7.9e-43 144.5 0.1 1.4e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EGO61096.1 - 3.2e-16 59.0 0.2 1.5e-15 56.9 0.1 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGO61096.1 - 2e-11 43.6 2.9 3.2e-11 42.9 0.1 2.7 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGO61096.1 - 7e-11 42.1 0.0 2e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGO61096.1 - 8.9e-09 35.4 0.0 2.4e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGO61096.1 - 1.8e-07 31.5 0.1 5.4e-07 30.0 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGO61096.1 - 0.00066 19.6 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NIF PF03031.13 EGO61097.1 - 1.3e-19 70.4 0.0 2.3e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF947 PF06102.7 EGO61098.1 - 8.6e-57 191.6 24.6 8.6e-57 191.6 17.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF947) BSP_II PF05432.6 EGO61098.1 - 0.13 11.5 18.7 0.24 10.6 13.0 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CD34_antigen PF06365.7 EGO61098.1 - 0.17 11.5 4.6 0.32 10.6 3.2 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family IncA PF04156.9 EGO61098.1 - 0.3 10.6 5.9 0.56 9.7 4.1 1.4 1 0 0 1 1 1 0 IncA protein ABC1 PF03109.11 EGO61099.1 - 1.3e-31 109.0 0.0 3.2e-31 107.7 0.0 1.7 1 0 0 1 1 1 1 ABC1 family Es2 PF09751.4 EGO61100.1 - 4.1e-112 375.6 3.9 4.8e-112 375.4 2.7 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 DUF3878 PF12994.2 EGO61100.1 - 0.11 11.6 0.2 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) DUF3344 PF11824.3 EGO61100.1 - 0.13 11.6 0.2 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) Hus1 PF04005.7 EGO61101.1 - 4.2e-88 295.0 0.0 5.6e-88 294.6 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein zf-RING_2 PF13639.1 EGO61101.1 - 5.1e-10 39.0 7.4 8.6e-10 38.2 3.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGO61101.1 - 2.6e-07 30.1 3.1 2.6e-07 30.1 2.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO61101.1 - 1e-06 28.6 5.8 1e-06 28.6 4.0 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGO61101.1 - 3.9e-06 26.8 2.5 3.9e-06 26.8 1.7 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGO61101.1 - 8.4e-06 25.3 4.3 8.4e-06 25.3 3.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO61101.1 - 2.6e-05 23.8 2.9 7e-05 22.4 2.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGO61101.1 - 0.00041 20.0 0.6 0.00041 20.0 0.4 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EGO61101.1 - 0.0059 16.4 3.6 0.017 14.9 2.5 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EGO61101.1 - 0.0063 16.0 2.5 0.013 15.0 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EGO61101.1 - 2.4 8.0 10.7 0.51 10.2 3.9 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Sec16_C PF12931.2 EGO61102.1 - 9.6e-96 320.8 0.0 1.3e-95 320.3 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EGO61102.1 - 8e-32 109.6 0.0 1.7e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Hydrolase PF00702.21 EGO61103.1 - 1.7e-16 61.2 0.0 5.7e-16 59.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGO61103.1 - 4.2e-16 58.6 0.0 1.1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EGO61103.1 - 1.3e-10 41.7 0.0 4.1e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO61103.1 - 0.00011 22.0 0.0 0.00043 20.1 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGO61103.1 - 0.001 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Suc_Fer-like PF06999.7 EGO61104.1 - 4.9e-74 249.2 0.0 5.9e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Methyltransf_26 PF13659.1 EGO61105.1 - 1.4e-09 37.9 0.0 3.5e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO61105.1 - 6.5e-08 32.2 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO61105.1 - 4.6e-05 23.9 0.0 7.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO61105.1 - 0.0016 17.8 0.0 0.0047 16.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EGO61105.1 - 0.0024 17.5 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO61105.1 - 0.03 13.4 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGO61105.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EGO61105.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) N6_Mtase PF02384.11 EGO61105.1 - 0.14 11.2 0.0 0.28 10.2 0.0 1.4 2 0 0 2 2 2 0 N-6 DNA Methylase FAD_binding_6 PF00970.19 EGO61106.1 - 4.4e-09 36.3 0.0 1.2e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGO61106.1 - 0.0024 18.4 0.0 0.0064 17.0 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain AA_permease_2 PF13520.1 EGO61107.1 - 4.1e-65 219.9 40.5 5.5e-65 219.5 28.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO61107.1 - 7.7e-30 103.6 29.2 7.7e-30 103.6 20.3 2.1 2 0 0 2 2 2 1 Amino acid permease tRNA-synt_1 PF00133.17 EGO61108.1 - 2.3e-56 191.0 0.0 1.2e-20 73.0 0.1 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EGO61108.1 - 1.6e-41 141.6 0.0 3.5e-41 140.5 0.0 1.6 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EGO61108.1 - 2e-34 118.9 0.2 7.5e-25 87.3 0.1 4.3 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EGO61108.1 - 2.4e-12 46.8 0.0 5.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 EGO61108.1 - 0.0009 18.1 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EGO61108.1 - 0.014 14.5 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain 2-Hacid_dh_C PF02826.14 EGO61109.1 - 9.1e-54 181.2 0.0 1.3e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGO61109.1 - 2.5e-16 59.3 0.0 3.7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGO61109.1 - 2.5e-06 27.4 0.0 9.5e-06 25.5 0.0 1.9 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EGO61109.1 - 0.0049 16.2 0.0 0.015 14.6 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain GFO_IDH_MocA PF01408.17 EGO61109.1 - 0.0094 16.4 0.0 0.034 14.6 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.15 EGO61109.1 - 0.029 14.4 0.0 0.15 12.1 0.0 2.1 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_C PF03720.10 EGO61109.1 - 0.1 12.7 0.0 0.48 10.6 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DUF3684 PF12449.3 EGO61110.1 - 0 1447.3 0.0 0 1447.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) MMtag PF10159.4 EGO61110.1 - 2.3e-29 101.2 3.4 2.3e-29 101.2 2.4 3.0 3 0 0 3 3 3 1 Kinase phosphorylation protein HATPase_c_3 PF13589.1 EGO61110.1 - 1.5e-05 24.6 0.0 6.2e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Stn1_C PF12659.2 EGO61110.1 - 0.025 14.3 0.1 0.089 12.6 0.0 1.9 2 0 0 2 2 2 0 Telomere capping C-terminal wHTH Reprolysin_5 PF13688.1 EGO61110.1 - 0.077 12.9 0.1 0.25 11.2 0.1 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12 Med6 PF04934.9 EGO61111.1 - 2.5e-40 137.2 0.0 3.2e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component HA2 PF04408.18 EGO61112.1 - 1.1e-19 70.3 0.0 3.7e-19 68.6 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGO61112.1 - 2.9e-17 62.5 0.0 6.1e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGO61112.1 - 1.2e-12 47.4 0.0 7.3e-12 44.9 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGO61112.1 - 7.2e-08 32.1 0.1 1.2e-06 28.1 0.1 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EGO61112.1 - 0.0014 18.4 1.2 0.44 10.3 0.0 3.3 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EGO61112.1 - 0.0038 17.3 0.7 0.04 14.0 0.5 2.5 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EGO61112.1 - 0.011 14.6 0.0 0.028 13.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EGO61112.1 - 0.027 13.7 0.1 0.075 12.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_23 PF13476.1 EGO61112.1 - 0.043 14.1 10.6 0.24 11.6 0.0 3.6 4 0 0 4 4 4 0 AAA domain KaiC PF06745.8 EGO61112.1 - 0.073 12.1 1.0 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 KaiC DUF2372 PF10178.4 EGO61113.1 - 0.0024 17.9 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) dUTPase PF00692.14 EGO61113.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 dUTPase Ribosomal_L18e PF00828.14 EGO61114.1 - 1.3e-33 116.1 0.1 1.8e-33 115.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Cyclase PF04199.8 EGO61115.1 - 5.3e-08 32.7 0.0 9.6e-08 31.9 0.0 1.4 1 1 0 1 1 1 1 Putative cyclase Metallophos PF00149.23 EGO61117.1 - 3.2e-42 144.1 1.3 5.3e-42 143.4 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase adh_short PF00106.20 EGO61118.1 - 1.2e-24 87.0 0.8 2e-24 86.3 0.6 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO61118.1 - 7.2e-17 61.9 0.1 1e-16 61.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO61118.1 - 1.8e-08 34.2 0.7 6.7e-08 32.3 0.5 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EGO61118.1 - 0.0056 16.1 0.1 0.22 10.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EGO61118.1 - 0.016 14.8 0.2 0.025 14.2 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EGO61118.1 - 0.028 14.2 0.5 0.069 12.9 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EGO61118.1 - 0.072 12.2 0.6 0.1 11.7 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TauD PF02668.11 EGO61119.1 - 2.3e-32 112.7 0.0 3.5e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EGO61119.1 - 1.3e-06 28.7 0.0 3.1e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF971) PhoD PF09423.5 EGO61120.1 - 2.4e-69 234.0 0.0 2.9e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase EMP24_GP25L PF01105.19 EGO61121.1 - 5.1e-46 156.6 2.6 5.8e-46 156.5 1.8 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SKIP_SNW PF02731.10 EGO61122.1 - 1.3e-67 226.2 5.7 1.3e-67 226.2 3.9 2.3 2 0 0 2 2 2 1 SKIP/SNW domain Dehydrin PF00257.14 EGO61122.1 - 0.006 16.9 0.8 0.011 16.1 0.6 1.6 1 0 0 1 1 1 1 Dehydrin Tim17 PF02466.14 EGO61123.1 - 5.6e-52 175.1 7.7 8e-52 174.6 5.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 EGO61123.1 - 0.0022 17.9 0.2 0.037 13.9 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF543) USP7_ICP0_bdg PF12436.3 EGO61125.1 - 8.3e-88 293.8 0.4 8e-85 284.0 0.0 3.2 2 1 1 3 3 3 3 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EGO61125.1 - 2.7e-71 239.4 12.3 3.9e-71 238.8 1.4 4.0 4 1 1 5 5 5 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 EGO61125.1 - 4.7e-48 163.6 0.9 4.8e-40 137.3 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGO61125.1 - 2.9e-25 89.2 0.8 7.6e-18 64.9 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EGO61125.1 - 3.4e-12 46.6 0.7 1.9e-11 44.2 0.0 2.6 3 0 0 3 3 3 1 MATH domain BCDHK_Adom3 PF10436.4 EGO61126.1 - 3.7e-40 137.1 0.4 9.4e-40 135.8 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EGO61126.1 - 3e-09 36.5 0.0 1.6e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGO61126.1 - 0.00036 20.2 0.0 0.00076 19.1 0.0 1.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Septin PF00735.13 EGO61127.1 - 1.4e-116 388.4 0.2 2.2e-116 387.8 0.1 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EGO61127.1 - 6.2e-07 29.3 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO61127.1 - 4.7e-06 26.1 0.2 5.7e-05 22.6 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EGO61127.1 - 1.1e-05 24.6 0.0 2.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EGO61127.1 - 0.0023 18.4 0.1 0.0081 16.6 0.1 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EGO61127.1 - 0.0033 17.0 0.1 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGO61127.1 - 0.0039 17.3 0.4 0.015 15.4 0.0 2.1 2 2 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EGO61127.1 - 0.0056 16.1 0.0 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family AIG1 PF04548.11 EGO61127.1 - 0.007 15.4 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 EGO61127.1 - 0.0074 15.1 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 EGO61127.1 - 0.013 14.8 0.1 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 EGO61127.1 - 0.019 14.3 0.8 0.054 12.8 0.4 1.9 2 1 0 2 2 2 0 Ras family T2SE PF00437.15 EGO61127.1 - 0.035 12.9 0.4 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.7 EGO61127.1 - 0.04 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EGO61127.1 - 0.049 13.9 0.1 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.18 EGO61127.1 - 0.062 13.1 7.3 0.68 9.7 0.1 3.1 2 1 1 3 3 3 0 Dynamin family DUF2968 PF11180.3 EGO61127.1 - 0.068 12.5 4.9 0.17 11.2 3.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) PduV-EutP PF10662.4 EGO61127.1 - 0.069 12.6 0.3 2.8 7.4 0.2 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 EGO61127.1 - 0.071 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 EGO61127.1 - 0.079 11.9 0.9 0.11 11.4 0.6 1.6 1 1 0 1 1 1 0 KAP family P-loop domain ArgK PF03308.11 EGO61127.1 - 0.11 11.2 1.2 0.92 8.2 0.0 2.7 3 0 0 3 3 3 0 ArgK protein AAA_16 PF13191.1 EGO61127.1 - 0.11 12.4 1.6 0.42 10.5 0.0 2.5 2 1 1 3 3 3 0 AAA ATPase domain Ribosomal_L6e PF01159.14 EGO61127.1 - 0.12 12.5 4.5 3.8 7.7 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e RNA_helicase PF00910.17 EGO61127.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Myc-LZ PF02344.10 EGO61127.1 - 0.22 11.1 5.5 0.22 11.1 0.3 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain AAA_23 PF13476.1 EGO61127.1 - 4.4 7.5 18.5 75 3.5 12.8 2.1 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 EGO61128.1 - 9.4e-54 177.4 34.3 3.5e-12 45.6 0.0 12.1 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 EGO61128.1 - 2.8e-26 91.5 0.0 4.2e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EGO61128.1 - 5.8e-07 29.4 2.4 0.064 12.9 0.1 5.8 5 1 1 7 7 7 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EGO61128.1 - 9.8e-05 20.3 0.0 0.0097 13.7 0.0 2.9 2 1 1 3 3 3 1 IKI3 family Nup160 PF11715.3 EGO61128.1 - 0.00056 18.1 0.5 0.93 7.5 0.1 3.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 EGO61128.1 - 0.0016 17.6 0.9 8.2 5.4 0.0 4.4 4 2 1 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Utp13 PF08625.6 EGO61128.1 - 0.075 12.6 0.2 0.3 10.7 0.1 2.1 2 1 0 2 2 2 0 Utp13 specific WD40 associated domain DUF4243 PF14027.1 EGO61129.1 - 2.2e-94 316.5 0.6 2.6e-94 316.3 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) RNA_replicase_B PF03431.8 EGO61129.1 - 0.013 13.7 0.0 0.018 13.3 0.0 1.1 1 0 0 1 1 1 0 RNA replicase, beta-chain Exo_endo_phos PF03372.18 EGO61132.1 - 2.3e-28 99.7 0.8 4.8e-28 98.7 0.5 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.1 EGO61132.1 - 0.0052 16.5 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EGO61132.1 - 0.27 11.5 3.9 9.6 6.6 0.0 3.9 3 0 0 3 3 3 0 PQQ-like domain PEHE PF15275.1 EGO61133.1 - 0.18 12.2 1.9 0.24 11.8 1.3 1.1 1 0 0 1 1 1 0 PEHE domain DUF1183 PF06682.7 EGO61133.1 - 0.23 11.0 5.2 0.078 12.5 1.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) CTD_bind PF04818.8 EGO61134.1 - 1.8e-09 37.7 0.0 3.3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. KAR9 PF08580.5 EGO61134.1 - 2 6.6 18.6 2.8 6.0 12.9 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF936 PF06075.7 EGO61134.1 - 3.5 6.4 18.1 6.7 5.5 12.6 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) MFS_1 PF07690.11 EGO61135.1 - 5.4e-44 150.3 39.3 3.9e-40 137.6 27.8 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO61135.1 - 2.7e-17 62.5 6.7 2.7e-17 62.5 4.7 3.6 3 1 1 4 4 4 2 Sugar (and other) transporter MFS_2 PF13347.1 EGO61135.1 - 6.1e-09 34.7 26.5 8.4e-06 24.4 1.2 3.2 3 0 0 3 3 3 2 MFS/sugar transport protein DUF1228 PF06779.9 EGO61135.1 - 1.9 8.5 9.7 0.55 10.3 0.9 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) PALP PF00291.20 EGO61136.1 - 1.5e-28 99.9 0.0 2.5e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 EGO61136.1 - 5.2e-09 36.4 0.0 1.5e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Grp1_Fun34_YaaH PF01184.14 EGO61137.1 - 1.7e-09 37.3 0.4 1.8e-09 37.2 0.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Pax7 PF12360.3 EGO61137.1 - 0.066 13.4 0.8 0.16 12.2 0.6 1.7 1 0 0 1 1 1 0 Paired box protein 7 Tau95 PF09734.4 EGO61138.1 - 3.3e-70 236.8 0.0 5.1e-70 236.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit B56 PF01603.15 EGO61139.1 - 3.8e-174 579.1 7.8 4.6e-174 578.8 5.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Dynamin_N PF00350.18 EGO61139.1 - 0.068 12.9 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Dynamin family AA_permease PF00324.16 EGO61142.1 - 4e-57 193.6 32.5 5.2e-57 193.2 22.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EGO61142.1 - 2.1e-19 69.4 42.2 3.1e-19 68.8 29.3 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 EGO61143.1 - 6e-83 278.6 36.4 7.2e-83 278.3 25.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RNA_pol_L_2 PF13656.1 EGO61144.1 - 1.3e-22 79.0 0.0 1.6e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EGO61144.1 - 1.6e-09 36.7 0.0 2.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain cobW PF02492.14 EGO61145.1 - 1e-37 129.2 0.0 1.8e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EGO61145.1 - 0.002 17.8 0.0 0.006 16.3 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EGO61145.1 - 0.0059 16.1 0.2 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase CobW_C PF07683.9 EGO61145.1 - 0.0086 15.7 0.0 0.07 12.8 0.0 2.4 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_19 PF13245.1 EGO61145.1 - 0.015 15.0 0.0 0.043 13.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EGO61145.1 - 0.029 13.7 0.0 0.06 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EGO61145.1 - 0.031 14.2 0.1 0.089 12.7 0.0 1.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EGO61145.1 - 0.035 14.2 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EGO61145.1 - 0.041 13.4 0.1 0.4 10.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EGO61145.1 - 0.054 13.8 0.3 0.17 12.1 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGO61145.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGO61145.1 - 0.098 12.3 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 NTPase ARD PF03079.9 EGO61146.1 - 0.03 14.2 1.4 0.041 13.8 1.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family DUF3523 PF12037.3 EGO61146.1 - 0.79 8.6 8.1 1.2 8.0 5.7 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3523) Dak1 PF02733.12 EGO61147.1 - 7.4e-104 346.8 14.8 8.6e-102 340.0 10.3 2.1 1 1 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EGO61147.1 - 1.2e-45 155.3 2.8 1.2e-45 155.3 1.9 1.8 2 0 0 2 2 2 1 DAK2 domain LSM PF01423.17 EGO61148.1 - 6.5e-19 67.2 0.2 8.7e-19 66.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain Baculo_44 PF04631.7 EGO61148.1 - 0.042 12.4 0.0 0.048 12.2 0.0 1.1 1 0 0 1 1 1 0 Baculovirus hypothetical protein ECH_C PF13766.1 EGO61149.1 - 4.9e-34 117.0 0.0 3.7e-33 114.1 0.0 2.1 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EGO61149.1 - 8.5e-25 87.2 0.0 1.8e-23 82.9 0.0 2.1 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family ABC_tran PF00005.22 EGO61150.1 - 1.5e-40 138.6 0.0 3.1e-20 72.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EGO61150.1 - 1e-29 103.8 9.0 2.4e-24 86.2 3.2 3.2 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EGO61150.1 - 4e-15 56.5 0.0 0.011 15.6 0.0 4.3 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 EGO61150.1 - 1.6e-11 43.9 5.1 0.0064 15.7 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGO61150.1 - 7.4e-08 32.5 0.4 0.0083 16.1 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EGO61150.1 - 1e-07 32.1 2.2 0.024 14.7 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGO61150.1 - 8.6e-07 28.3 2.9 0.0077 15.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EGO61150.1 - 4.9e-06 26.0 3.3 0.013 14.8 0.1 3.3 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 EGO61150.1 - 9e-06 25.4 1.0 0.19 11.4 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EGO61150.1 - 1.1e-05 25.3 2.0 0.1 12.4 0.0 3.2 4 0 0 4 4 2 2 AAA domain DUF258 PF03193.11 EGO61150.1 - 1.9e-05 23.9 0.2 0.0081 15.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGO61150.1 - 4.1e-05 23.4 6.5 0.00038 20.3 0.3 2.9 3 0 0 3 3 3 1 Dynamin family AAA_17 PF13207.1 EGO61150.1 - 4.8e-05 24.1 0.9 0.3 11.8 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EGO61150.1 - 5.3e-05 22.8 5.0 0.064 12.6 0.0 3.6 4 0 0 4 4 4 2 AAA-like domain ATP_bind_1 PF03029.12 EGO61150.1 - 6.9e-05 22.4 0.1 0.34 10.4 0.0 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 EGO61150.1 - 8.2e-05 23.0 2.8 0.0089 16.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EGO61150.1 - 0.00023 20.7 1.0 0.015 14.7 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 EGO61150.1 - 0.00025 21.5 0.1 0.71 10.3 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein Pox_A32 PF04665.7 EGO61150.1 - 0.0004 19.7 0.6 0.007 15.6 0.1 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein NACHT PF05729.7 EGO61150.1 - 0.00042 20.0 1.6 0.95 9.1 0.0 3.3 3 1 1 4 4 3 2 NACHT domain AAA_18 PF13238.1 EGO61150.1 - 0.0014 18.8 0.0 2.6 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EGO61150.1 - 0.0016 17.9 3.3 0.14 11.5 0.2 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 EGO61150.1 - 0.0022 17.9 0.1 0.59 10.1 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase Adeno_IVa2 PF02456.10 EGO61150.1 - 0.0023 16.6 0.1 0.01 14.5 0.0 1.9 2 0 0 2 2 2 1 Adenovirus IVa2 protein T2SE PF00437.15 EGO61150.1 - 0.0042 16.0 4.2 0.16 10.8 0.3 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_24 PF13479.1 EGO61150.1 - 0.0059 16.2 1.5 0.42 10.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGO61150.1 - 0.0068 16.3 0.1 3.8 7.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.16 EGO61150.1 - 0.0088 15.2 0.8 0.092 11.8 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGO61150.1 - 0.013 15.1 0.2 4.1 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EGO61150.1 - 0.016 15.1 1.1 0.27 11.1 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EGO61150.1 - 0.018 14.8 5.4 0.97 9.2 0.1 3.5 4 0 0 4 4 2 0 Part of AAA domain AAA PF00004.24 EGO61150.1 - 0.024 14.8 1.1 12 6.1 0.0 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Pex14_N PF04695.8 EGO61150.1 - 0.028 14.4 1.6 7.2 6.6 0.1 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_30 PF13604.1 EGO61150.1 - 0.035 13.6 4.8 7.3 6.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 EGO61150.1 - 0.04 13.3 0.9 0.33 10.3 0.0 2.5 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain Septin PF00735.13 EGO61150.1 - 0.05 12.6 0.3 8 5.3 0.1 2.3 2 0 0 2 2 2 0 Septin ABC_ATPase PF09818.4 EGO61150.1 - 0.065 11.8 0.3 1.6 7.2 0.1 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RNA_helicase PF00910.17 EGO61150.1 - 0.087 13.0 0.3 20 5.4 0.0 3.1 3 0 0 3 3 2 0 RNA helicase Arch_ATPase PF01637.13 EGO61150.1 - 0.11 12.1 1.2 11 5.6 0.0 2.9 2 1 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 EGO61150.1 - 0.12 11.8 0.1 10 5.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EGO61150.1 - 0.12 12.3 1.8 8.2 6.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EGO61150.1 - 1.4 8.6 5.4 8.5 6.1 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 NTPase_1 PF03266.10 EGO61150.1 - 3.3 7.3 6.7 28 4.3 0.0 3.3 3 0 0 3 3 3 0 NTPase DUF1754 PF08555.5 EGO61152.1 - 5.5e-20 71.7 17.3 9e-20 71.1 12.0 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) SART-1 PF03343.8 EGO61152.1 - 0.065 11.5 20.3 0.078 11.3 14.0 1.0 1 0 0 1 1 1 0 SART-1 family CDC27 PF09507.5 EGO61152.1 - 0.088 12.0 16.1 0.1 11.8 11.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Gemini_AL2 PF01440.11 EGO61152.1 - 0.091 12.8 3.4 0.15 12.1 2.3 1.4 1 0 0 1 1 1 0 Geminivirus AL2 protein DUF2265 PF10023.4 EGO61152.1 - 0.49 9.4 2.5 0.67 9.0 1.7 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) PA26 PF04636.8 EGO61152.1 - 0.57 8.8 6.1 0.69 8.5 4.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DDHD PF02862.12 EGO61152.1 - 0.81 9.4 7.8 1.1 8.9 5.4 1.2 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 EGO61152.1 - 1.5 6.7 13.3 1.6 6.6 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein IFT57 PF10498.4 EGO61152.1 - 2 7.0 12.6 2.5 6.7 8.7 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FAM60A PF15396.1 EGO61152.1 - 2.2 7.9 9.0 2.9 7.5 6.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A End3 PF12761.2 EGO61152.1 - 4.1 7.0 15.6 2.1 7.9 4.6 1.9 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Atg14 PF10186.4 EGO61152.1 - 4.1 6.2 14.8 5.1 5.9 10.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EGO61152.1 - 4.2 6.9 14.3 5.2 6.6 9.9 1.3 1 1 0 1 1 1 0 IncA protein RR_TM4-6 PF06459.7 EGO61152.1 - 5 6.9 12.6 6 6.6 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 U3_snoRNA_assoc PF08297.6 EGO61152.1 - 6.2 7.1 17.8 0.036 14.3 3.5 2.5 1 1 2 3 3 3 0 U3 snoRNA associated DUF1206 PF06724.6 EGO61153.1 - 3.8 7.3 6.4 0.31 10.8 0.5 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) CTP_transf_1 PF01148.15 EGO61155.1 - 8.8e-06 25.5 18.6 8.1e-05 22.4 10.4 2.9 2 1 0 2 2 2 1 Cytidylyltransferase family Glyco_hydro_76 PF03663.9 EGO61156.1 - 2.6e-143 477.8 15.5 3.2e-143 477.5 10.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 NAP PF00956.13 EGO61157.1 - 1.4e-42 145.4 12.1 1.4e-42 145.4 8.4 2.4 2 1 0 2 2 1 1 Nucleosome assembly protein (NAP) Nucleoplasmin PF03066.10 EGO61157.1 - 0.0027 17.2 28.3 0.012 15.1 5.2 2.5 2 0 0 2 2 2 2 Nucleoplasmin NARP1 PF12569.3 EGO61157.1 - 0.044 12.5 6.7 0.062 12.0 4.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Adeno_terminal PF02459.10 EGO61157.1 - 0.062 11.4 6.0 0.099 10.7 4.1 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein BUD22 PF09073.5 EGO61157.1 - 0.091 11.8 23.4 0.12 11.4 16.2 1.2 1 0 0 1 1 1 0 BUD22 PgaD PF13994.1 EGO61157.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 PgaD-like protein Serinc PF03348.10 EGO61157.1 - 0.34 9.5 0.4 0.5 9.0 0.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4366 PF14283.1 EGO61157.1 - 0.43 9.9 20.4 0.97 8.8 14.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Ycf1 PF05758.7 EGO61157.1 - 0.45 8.1 3.2 0.54 7.8 2.2 1.2 1 0 0 1 1 1 0 Ycf1 DUF4407 PF14362.1 EGO61157.1 - 0.72 8.7 4.7 1.6 7.6 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Drc1-Sld2 PF11719.3 EGO61157.1 - 0.95 8.4 12.2 0.13 11.3 5.9 1.4 2 0 0 2 2 2 0 DNA replication and checkpoint protein PBP_sp32 PF07222.7 EGO61157.1 - 0.99 8.5 11.7 1.8 7.6 8.1 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Sec62 PF03839.11 EGO61157.1 - 1.7 8.0 4.4 3.9 6.8 3.0 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 DDHD PF02862.12 EGO61157.1 - 1.9 8.2 7.4 0.21 11.3 2.2 1.5 2 0 0 2 2 2 0 DDHD domain Myc_N PF01056.13 EGO61157.1 - 2.7 7.0 24.4 0.51 9.4 8.8 2.3 2 0 0 2 2 2 0 Myc amino-terminal region MscS_TM PF12794.2 EGO61157.1 - 3.2 6.2 7.1 4.7 5.7 4.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 CENP-B_dimeris PF09026.5 EGO61157.1 - 3.2 8.0 35.2 1.3 9.2 9.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain APG6 PF04111.7 EGO61157.1 - 3.7 6.5 12.1 8.9 5.2 5.4 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 TFIIA PF03153.8 EGO61157.1 - 4.6 7.0 18.4 6.9 6.4 12.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 EGO61157.1 - 5.2 4.9 21.3 0.12 10.3 4.0 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF572 PF04502.8 EGO61157.1 - 6.5 5.8 17.3 12 5.0 12.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) YL1 PF05764.8 EGO61157.1 - 8.9 5.8 31.7 2.4 7.7 1.3 2.4 1 1 1 2 2 2 0 YL1 nuclear protein Asparaginase PF00710.15 EGO61158.1 - 7.2e-101 337.1 0.0 9.4e-101 336.7 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank PF00023.25 EGO61158.1 - 1.1e-11 43.9 0.1 0.0004 20.0 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EGO61158.1 - 4e-11 43.1 0.1 9.1e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGO61158.1 - 5.2e-09 36.3 0.1 0.00035 20.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGO61158.1 - 3.7e-07 29.7 0.2 0.064 13.5 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGO61158.1 - 3.8e-06 26.9 0.2 0.005 17.0 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) BCS1_N PF08740.6 EGO61159.1 - 7.5e-48 162.6 0.2 7.5e-48 162.6 0.1 2.1 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 EGO61159.1 - 1.1e-15 58.0 0.3 7.5e-07 29.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EGO61159.1 - 2.3e-05 24.0 0.7 7.7e-05 22.3 0.5 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGO61159.1 - 0.00093 20.0 0.0 0.0031 18.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGO61159.1 - 0.0042 16.8 0.0 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EGO61159.1 - 0.0056 16.1 0.2 0.2 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGO61159.1 - 0.0081 16.0 0.0 0.039 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGO61159.1 - 0.029 14.6 2.6 0.42 10.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EGO61159.1 - 0.084 12.8 0.9 0.45 10.4 0.4 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 EGO61159.1 - 0.16 11.7 4.8 1.2 8.9 0.0 3.5 3 0 0 3 3 3 0 Part of AAA domain LSM PF01423.17 EGO61160.1 - 7.7e-21 73.4 0.2 8.6e-21 73.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGO61160.1 - 0.078 12.9 0.0 0.089 12.7 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain DNA_pol_A_exo1 PF01612.15 EGO61161.1 - 1.1e-12 47.7 0.0 2.1e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Herpes_IE1 PF07340.6 EGO61161.1 - 0.082 11.3 0.1 0.13 10.6 0.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein WD40 PF00400.27 EGO61162.1 - 4.1e-32 108.8 11.7 2.3e-07 30.4 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat NLE PF08154.7 EGO61162.1 - 4.9e-20 71.3 0.2 1e-19 70.3 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EGO61162.1 - 0.0011 17.1 2.9 0.73 7.9 1.0 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGO61162.1 - 0.017 13.9 4.1 1.1 7.9 0.4 3.1 1 1 1 2 2 2 0 Nup133 N terminal like DNA_pol_E_B PF04042.11 EGO61163.1 - 4.7e-58 195.8 0.0 6.4e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CAP_N PF01213.14 EGO61164.1 - 0.37 10.0 2.2 0.85 8.8 1.6 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Nucleoplasmin PF03066.10 EGO61164.1 - 1.8 8.0 7.4 3.4 7.1 5.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EGO61164.1 - 2.9 7.0 6.2 5.4 6.1 4.3 1.3 1 0 0 1 1 1 0 NOA36 protein PALP PF00291.20 EGO61165.1 - 9.6e-61 205.6 0.3 1.1e-60 205.4 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Acetyltransf_3 PF13302.1 EGO61166.1 - 1.5e-27 96.5 0.0 1.8e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGO61166.1 - 1.3e-09 38.0 0.3 0.00016 21.5 0.3 2.8 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO61166.1 - 8.5e-07 28.6 0.0 0.013 15.1 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_4 PF13420.1 EGO61166.1 - 4.1e-05 23.5 0.0 0.0009 19.2 0.0 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO61166.1 - 0.00028 20.8 0.0 0.0052 16.7 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family XPG_I_2 PF12813.2 EGO61166.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing tRNA-synt_1g PF09334.6 EGO61167.1 - 3.9e-124 414.2 1.7 7.2e-124 413.3 1.2 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGO61167.1 - 1.7e-25 89.0 6.5 1.1e-09 36.9 0.3 4.0 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EGO61167.1 - 6e-09 35.4 0.1 0.0016 17.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Peptidase_C28 PF05408.6 EGO61167.1 - 0.054 12.9 0.1 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Foot-and-mouth virus L-proteinase Peripla_BP_3 PF13377.1 EGO61167.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Periplasmic binding protein-like domain DUF3039 PF11238.3 EGO61168.1 - 0.031 13.7 0.1 9 5.8 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) Trm112p PF03966.11 EGO61168.1 - 0.09 13.1 0.1 2.7 8.4 0.0 2.8 2 0 0 2 2 2 0 Trm112p-like protein Ribosomal_L4 PF00573.17 EGO61170.1 - 1.1e-41 142.3 0.8 1.7e-41 141.7 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EGO61170.1 - 2.9e-30 103.9 1.3 2.9e-30 103.9 0.9 2.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Aminotran_1_2 PF00155.16 EGO61171.1 - 2.5e-10 39.8 0.0 3e-08 33.0 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class I and II FMO-like PF00743.14 EGO61172.1 - 1e-43 149.3 0.0 3e-25 88.4 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGO61172.1 - 1.3e-17 64.4 0.0 1.1e-16 61.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGO61172.1 - 2.2e-17 63.2 0.0 1.4e-16 60.6 0.0 2.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EGO61172.1 - 3.8e-13 49.0 0.4 8.2e-10 38.1 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGO61172.1 - 3.5e-10 40.1 0.0 5.2e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO61172.1 - 4.3e-09 36.2 0.0 1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGO61172.1 - 9e-07 28.2 0.1 9.9e-05 21.5 0.0 2.7 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 EGO61172.1 - 7.1e-06 25.1 0.1 0.0061 15.5 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EGO61172.1 - 0.0002 20.5 0.1 0.0092 15.1 0.0 2.8 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EGO61172.1 - 0.0019 18.5 0.1 0.14 12.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EGO61172.1 - 0.0053 16.8 0.0 0.016 15.3 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DJ-1_PfpI PF01965.19 EGO61172.1 - 0.0062 15.9 0.0 2.7 7.4 0.0 2.5 2 0 0 2 2 2 2 DJ-1/PfpI family HI0933_like PF03486.9 EGO61172.1 - 0.0095 14.4 0.5 0.057 11.8 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FtsK_SpoIIIE_N PF12538.3 EGO61172.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 DNA transporter FAD_binding_2 PF00890.19 EGO61172.1 - 0.13 11.0 0.1 0.99 8.1 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Strep_67kDa_ant PF06100.6 EGO61172.1 - 0.14 10.5 0.0 0.27 9.5 0.0 1.4 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family DUF2823 PF11034.3 EGO61174.1 - 5.9e-36 122.4 11.6 6.6e-36 122.2 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) MT0933_antitox PF14013.1 EGO61174.1 - 0.081 13.0 5.4 3.6 7.7 3.6 2.2 1 1 0 1 1 1 0 MT0933-like antitoxin protein EBP PF05241.7 EGO61176.1 - 1.6e-77 258.8 8.5 2e-77 258.6 5.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein Herpes_pp38 PF04846.8 EGO61176.1 - 0.021 14.1 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein DUF788 PF05620.6 EGO61176.1 - 3.7 7.3 6.9 0.28 11.0 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF788) Lactamase_B PF00753.22 EGO61179.1 - 1.8e-28 99.5 2.0 2.9e-28 98.8 1.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGO61179.1 - 4e-07 29.7 0.1 5.2e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Peripla_BP_4 PF13407.1 EGO61179.1 - 0.067 12.5 0.0 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding protein domain Las1 PF04031.8 EGO61180.1 - 5.8e-67 224.1 0.0 7.5e-67 223.7 0.0 1.1 1 0 0 1 1 1 1 Las1-like DUF2201_N PF13203.1 EGO61180.1 - 0.038 13.1 6.4 0.56 9.3 1.5 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain Cut8_N PF14482.1 EGO61180.1 - 0.089 12.8 0.8 0.27 11.2 0.5 1.8 1 0 0 1 1 1 0 Cut8 proteasome-binding domain Saccharop_dh PF03435.13 EGO61181.1 - 1.2e-135 452.3 0.0 1.4e-135 452.2 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EGO61181.1 - 7.1e-06 26.1 0.4 1.2e-05 25.3 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EGO61181.1 - 2.6e-05 24.3 0.1 5.3e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 EGO61181.1 - 0.0024 17.2 0.1 0.15 11.4 0.0 2.9 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain GFO_IDH_MocA PF01408.17 EGO61181.1 - 0.0058 17.1 0.6 0.021 15.3 0.1 2.1 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 EGO61181.1 - 0.085 12.8 0.2 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain Nucleoplasmin PF03066.10 EGO61182.1 - 1.2 8.6 6.2 1.8 8.0 4.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4231 PF14015.1 EGO61183.1 - 0.22 11.5 0.7 0.27 11.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF2946 PF11162.3 EGO61184.1 - 0.098 12.8 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) CDK2AP PF09806.4 EGO61185.1 - 0.03 14.5 3.5 0.047 13.9 2.4 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PfkB PF00294.19 EGO61185.1 - 0.085 11.9 0.0 0.34 10.0 0.0 1.8 2 0 0 2 2 2 0 pfkB family carbohydrate kinase NAD_kinase PF01513.16 EGO61186.1 - 1.8e-69 233.6 0.0 7.6e-69 231.6 0.0 1.8 1 1 0 1 1 1 1 ATP-NAD kinase zf-rbx1 PF12678.2 EGO61187.1 - 1.4e-09 37.8 0.4 2.9e-09 36.9 0.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGO61187.1 - 1.9e-09 37.1 3.8 4.7e-09 35.9 0.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EGO61187.1 - 1.3e-06 27.9 0.7 2.2e-06 27.1 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO61187.1 - 1.7e-06 27.6 4.0 7.3e-06 25.6 2.8 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGO61187.1 - 5.5e-06 25.9 1.5 1.8e-05 24.3 0.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO61187.1 - 6.8e-05 22.8 2.5 6.8e-05 22.8 1.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2921 PF11145.3 EGO61187.1 - 0.0028 15.4 0.1 0.0044 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) zf-Apc11 PF12861.2 EGO61187.1 - 0.0059 16.4 0.9 0.014 15.2 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PQ-loop PF04193.9 EGO61187.1 - 0.0078 15.7 0.8 0.028 13.9 0.5 2.0 1 0 0 1 1 1 1 PQ loop repeat zf-RING_UBOX PF13445.1 EGO61187.1 - 0.0092 15.6 3.1 0.016 14.9 0.8 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGO61187.1 - 7.1 6.5 5.8 36 4.3 1.2 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING HSBP1 PF06825.7 EGO61188.1 - 4.6e-15 54.9 0.8 5.7e-15 54.6 0.5 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 EGO61188.1 - 0.017 14.4 0.7 0.3 10.4 0.1 2.2 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin SF-assemblin PF06705.6 EGO61188.1 - 0.018 14.1 0.1 0.021 13.9 0.0 1.0 1 0 0 1 1 1 0 SF-assemblin/beta giardin Baculo_PEP_C PF04513.7 EGO61188.1 - 0.02 14.7 0.6 0.023 14.5 0.4 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 EGO61188.1 - 0.033 13.6 0.1 0.037 13.5 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Corona_S2 PF01601.11 EGO61188.1 - 0.068 11.2 0.2 0.073 11.1 0.1 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF1664 PF07889.7 EGO61188.1 - 0.074 12.8 0.1 0.15 11.9 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2884 PF11101.3 EGO61188.1 - 0.13 11.5 0.2 0.14 11.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) TMV_coat PF00721.16 EGO61188.1 - 0.19 11.6 1.4 0.41 10.5 0.8 1.6 1 1 1 2 2 2 0 Virus coat protein (TMV like) Thioredoxin PF00085.15 EGO61189.1 - 3.8e-62 206.4 0.0 7.4e-31 105.9 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EGO61189.1 - 4.8e-27 94.4 0.6 1.4e-26 92.9 0.4 1.8 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EGO61189.1 - 2e-23 82.7 0.0 5.7e-11 42.6 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGO61189.1 - 2.7e-15 56.1 0.0 5.9e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EGO61189.1 - 1.3e-13 50.8 0.0 7.5e-06 25.9 0.0 3.3 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_6 PF13848.1 EGO61189.1 - 1.2e-07 31.7 0.0 0.0028 17.4 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EGO61189.1 - 8.9e-07 28.6 0.0 0.043 13.5 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EGO61189.1 - 2e-06 27.4 0.7 0.0088 15.5 0.0 2.4 1 1 0 2 2 2 2 Redoxin ERp29_N PF07912.8 EGO61189.1 - 2.6e-05 24.1 0.1 0.00032 20.6 0.0 2.6 3 0 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_3 PF13192.1 EGO61189.1 - 5.1e-05 23.0 0.0 0.055 13.2 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_4 PF13462.1 EGO61189.1 - 6.2e-05 23.0 0.0 0.5 10.3 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin Thioredoxin_9 PF14595.1 EGO61189.1 - 8.7e-05 22.0 0.0 0.15 11.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin AF0941-like PF14591.1 EGO61189.1 - 0.0015 18.5 0.8 0.0034 17.4 0.6 1.6 1 0 0 1 1 1 1 AF0941-like Glutaredoxin PF00462.19 EGO61189.1 - 0.0017 18.2 0.3 3.6 7.6 0.0 3.1 2 2 0 2 2 2 2 Glutaredoxin HyaE PF07449.6 EGO61189.1 - 0.013 15.4 0.1 0.15 12.0 0.0 2.6 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE DUF1910 PF08928.5 EGO61189.1 - 0.019 14.9 0.0 0.056 13.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) DSBA PF01323.15 EGO61189.1 - 0.038 13.5 1.6 24 4.4 0.0 4.0 3 2 2 5 5 5 0 DSBA-like thioredoxin domain DDE_Tnp_1_2 PF13586.1 EGO61189.1 - 0.078 13.1 0.0 12 6.1 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain DUF836 PF05768.9 EGO61189.1 - 0.13 12.5 0.0 2.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Ribosomal_S14 PF00253.16 EGO61190.1 - 2.9e-19 68.1 4.1 3.2e-19 68.0 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.7 EGO61190.1 - 0.044 13.8 0.9 4.3 7.4 0.1 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase GTP_EFTU PF00009.22 EGO61191.1 - 1.6e-59 200.5 0.1 2.2e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGO61191.1 - 4.5e-24 84.5 0.1 2.8e-23 81.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGO61191.1 - 5e-17 61.7 3.4 5e-17 61.7 2.3 2.2 2 1 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGO61191.1 - 2.9e-05 24.0 0.0 5.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EGO61191.1 - 0.00047 19.7 0.7 0.0011 18.5 0.5 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EGO61191.1 - 0.0016 18.9 0.0 0.0028 18.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EGO61191.1 - 0.12 11.8 0.5 13 5.2 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MARVEL PF01284.18 EGO61193.1 - 0.036 13.8 9.6 0.13 12.0 6.7 1.9 1 1 0 1 1 1 0 Membrane-associating domain Ribosomal_L37ae PF01780.14 EGO61194.1 - 1.4e-07 31.3 0.3 1.7e-07 31.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal L37ae protein family DnaJ PF00226.26 EGO61196.1 - 5e-29 99.8 2.2 8e-29 99.1 1.5 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGO61196.1 - 6e-25 86.9 4.2 8.1e-23 80.1 0.2 2.6 2 1 0 2 2 2 2 DnaJ C terminal domain HAD_2 PF13419.1 EGO61198.1 - 4.4e-19 69.3 0.0 5.7e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO61198.1 - 2.2e-12 47.8 0.0 1e-11 45.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO61198.1 - 1.6e-09 37.3 0.0 3.2e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 EGO61198.1 - 3e-05 23.7 0.0 0.002 17.8 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_6 PF13344.1 EGO61198.1 - 0.035 13.9 0.0 2.2 8.2 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Init_tRNA_PT PF04179.7 EGO61199.1 - 3.4e-164 547.0 0.0 3.9e-164 546.8 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Fungal_trans_2 PF11951.3 EGO61201.1 - 3.2e-06 26.0 0.0 1.2e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3402 PF11882.3 EGO61202.1 - 6.2e-164 545.9 0.0 9.5e-164 545.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EGO61202.1 - 1.2e-87 293.5 0.0 1.6e-87 293.0 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein DUF1183 PF06682.7 EGO61202.1 - 0.45 10.0 0.0 0.45 10.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1183) DUF2011 PF09428.5 EGO61203.1 - 2.8e-28 98.3 40.2 3.1e-28 98.2 22.7 3.0 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF2011) zf-HC2 PF13490.1 EGO61203.1 - 0.068 13.1 1.9 0.08 12.8 0.0 2.1 2 0 0 2 2 2 0 Putative zinc-finger NAM-associated PF14303.1 EGO61203.1 - 3 8.1 34.9 4.6 7.5 15.0 2.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain RR_TM4-6 PF06459.7 EGO61203.1 - 6.5 6.5 33.3 1.5 8.6 10.3 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NDT80_PhoG PF05224.7 EGO61204.1 - 7.2e-40 136.9 0.0 1.9e-39 135.6 0.0 1.7 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family AmiS_UreI PF02293.10 EGO61206.1 - 0.045 13.3 0.2 0.063 12.9 0.1 1.1 1 0 0 1 1 1 0 AmiS/UreI family transporter RWD PF05773.17 EGO61208.1 - 4.7e-25 87.6 0.0 1.1e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EGO61208.1 - 7.6e-21 73.7 37.2 1.5e-14 53.5 4.1 3.9 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EGO61208.1 - 4.8e-05 23.1 7.7 4.8e-05 23.1 5.3 3.6 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO61208.1 - 0.00018 21.4 8.9 0.00018 21.4 6.2 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO61208.1 - 0.0021 17.6 8.1 0.0021 17.6 5.6 4.1 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGO61208.1 - 8.5 6.1 18.0 0.02 14.6 2.5 2.8 2 0 0 2 2 2 0 RING-type zinc-finger PAP2 PF01569.16 EGO61209.1 - 2e-14 53.3 0.0 6.9e-14 51.6 0.0 1.8 1 1 1 2 2 2 1 PAP2 superfamily MgtC PF02308.11 EGO61209.1 - 0.026 14.3 0.1 0.045 13.5 0.1 1.3 1 0 0 1 1 1 0 MgtC family DUF212 PF02681.9 EGO61209.1 - 0.098 12.3 2.5 0.12 12.1 0.1 2.2 2 1 1 3 3 3 0 Divergent PAP2 family IF4E PF01652.13 EGO61210.1 - 9.2e-39 132.6 0.1 1.3e-38 132.1 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4598 PF15370.1 EGO61211.1 - 3.6e-07 30.4 0.3 3.6e-07 30.4 0.2 2.7 3 1 1 4 4 4 1 Domain of unknown function (DUF4598) Kinesin PF00225.18 EGO61212.1 - 1.6e-113 378.8 0.0 2.1e-113 378.4 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Cytochrom_B562 PF07361.6 EGO61212.1 - 0.1 12.9 2.4 0.32 11.4 1.7 1.8 1 0 0 1 1 1 0 Cytochrome b562 DUF972 PF06156.8 EGO61212.1 - 0.21 11.9 3.4 11 6.4 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) PUL PF08324.6 EGO61213.1 - 9.9e-58 195.0 0.0 1.3e-57 194.6 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 EGO61213.1 - 1.9e-14 53.6 0.0 6e-09 35.8 0.0 2.4 2 0 0 2 2 2 2 PPPDE putative peptidase domain Thioredoxin PF00085.15 EGO61213.1 - 7.4e-14 51.3 0.0 1.4e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EGO61213.1 - 0.0026 17.9 0.1 0.017 15.2 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EGO61213.1 - 0.019 14.6 0.1 0.054 13.1 0.0 1.8 1 1 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 EGO61213.1 - 0.032 13.7 0.1 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 Redoxin DUF1704 PF08014.6 EGO61213.1 - 0.084 11.8 0.5 0.16 10.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) TraF PF13728.1 EGO61213.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein GDA1_CD39 PF01150.12 EGO61215.1 - 2e-96 323.1 0.0 2.5e-96 322.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ras PF00071.17 EGO61217.1 - 3.4e-57 192.3 0.1 4.1e-57 192.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO61217.1 - 1.4e-18 67.5 0.0 2.1e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGO61217.1 - 7.4e-14 51.3 0.0 8.8e-14 51.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGO61217.1 - 1.6e-07 31.2 0.0 2.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGO61217.1 - 3.2e-07 29.9 0.0 9.9e-06 25.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGO61217.1 - 5.1e-07 29.0 0.0 6.2e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EGO61217.1 - 0.00069 19.7 0.0 0.0011 19.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGO61217.1 - 0.001 18.2 0.1 0.0019 17.4 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 EGO61217.1 - 0.0019 17.9 0.0 0.0064 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SRPRB PF09439.5 EGO61217.1 - 0.002 17.4 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EGO61217.1 - 0.0032 16.9 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EGO61217.1 - 0.0042 16.6 0.1 0.0077 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EGO61217.1 - 0.0045 16.5 0.4 0.15 11.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 EGO61217.1 - 0.0052 16.5 0.2 0.01 15.5 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 EGO61217.1 - 0.0059 16.6 0.0 0.011 15.7 0.0 1.5 2 0 0 2 2 1 1 AAA ATPase domain AAA_10 PF12846.2 EGO61217.1 - 0.0076 15.7 0.2 0.017 14.5 0.1 1.4 1 1 0 2 2 2 1 AAA-like domain Septin PF00735.13 EGO61217.1 - 0.015 14.3 0.3 0.032 13.2 0.0 1.7 2 1 0 2 2 2 0 Septin MobB PF03205.9 EGO61217.1 - 0.021 14.5 0.1 0.059 13.0 0.0 1.7 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EGO61217.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 NTPase cobW PF02492.14 EGO61217.1 - 0.031 13.7 0.0 0.079 12.4 0.0 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EGO61217.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 EGO61217.1 - 0.09 11.6 0.5 0.35 9.6 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 EGO61217.1 - 0.097 12.8 0.0 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 EGO61217.1 - 0.14 12.0 0.1 0.28 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain EamA PF00892.15 EGO61218.1 - 3.7e-06 26.9 29.3 4.2e-05 23.5 3.8 3.3 3 0 0 3 3 3 3 EamA-like transporter family EmrE PF13536.1 EGO61218.1 - 4.4e-06 26.8 21.7 0.00025 21.2 3.1 2.9 3 0 0 3 3 3 2 Multidrug resistance efflux transporter DUF914 PF06027.7 EGO61218.1 - 0.0004 19.3 1.2 0.0004 19.3 0.8 2.5 2 1 0 3 3 3 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 EGO61218.1 - 0.0014 18.2 23.3 0.12 12.0 1.6 3.0 2 1 0 2 2 2 2 Triose-phosphate Transporter family 7tm_7 PF08395.7 EGO61218.1 - 0.015 14.2 1.0 0.015 14.2 0.7 2.2 2 0 0 2 2 2 0 7tm Chemosensory receptor UAA PF08449.6 EGO61218.1 - 0.21 10.4 14.3 0.03 13.2 1.2 2.7 2 1 1 3 3 3 0 UAA transporter family FA_desaturase PF00487.19 EGO61218.1 - 2.2 7.6 15.4 0.48 9.8 0.1 3.6 3 1 0 3 3 3 0 Fatty acid desaturase Heme_oxygenase PF01126.15 EGO61219.1 - 2e-09 37.3 0.0 5e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Heme oxygenase Methyltransf_16 PF10294.4 EGO61220.1 - 7.8e-12 44.9 0.0 1.2e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGO61220.1 - 6.2e-05 23.5 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGO61220.1 - 0.00031 19.9 0.0 0.00046 19.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) zf-FPG_IleRS PF06827.9 EGO61222.1 - 0.15 11.7 1.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Antiterm PF03589.8 EGO61222.1 - 0.19 11.8 0.6 8.6 6.5 0.1 2.1 1 1 1 2 2 2 0 Antitermination protein DUF1660 PF07874.6 EGO61222.1 - 0.19 12.0 2.1 3.8 7.8 0.0 2.3 1 1 1 2 2 2 0 Prophage protein (DUF1660) Peptidase_C12 PF01088.16 EGO61224.1 - 1.7e-72 243.0 0.0 2.5e-72 242.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Fibrillarin PF01269.12 EGO61225.1 - 5.3e-107 355.9 0.0 6.6e-107 355.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EGO61225.1 - 3.1e-06 26.8 0.0 4.6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EGO61225.1 - 0.0041 16.6 0.1 0.0061 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EGO61225.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain zf-C2H2_4 PF13894.1 EGO61230.1 - 8.9e-05 22.5 16.8 0.12 12.7 0.0 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO61230.1 - 0.00021 21.4 19.6 1.5 9.3 0.0 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EGO61230.1 - 0.00087 19.1 1.3 0.066 13.1 0.7 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger DUF629 PF04780.7 EGO61230.1 - 0.17 10.3 0.3 0.42 9.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF629) NPR3 PF03666.8 EGO61232.1 - 2.4 6.5 4.0 2.8 6.3 2.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAD_binding_1 PF00667.15 EGO61233.1 - 1e-43 149.3 0.0 1.5e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EGO61233.1 - 1.3e-10 41.8 0.0 4.4e-10 40.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Nitroreductase PF00881.19 EGO61234.1 - 1.7e-16 60.4 0.0 2e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family Vps54 PF07928.7 EGO61234.1 - 0.015 15.3 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Vps54-like protein PS_Dcarbxylase PF02666.10 EGO61235.1 - 2.4e-81 271.8 0.0 3.2e-80 268.2 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase T_hemolysin PF12261.3 EGO61236.1 - 0.074 12.5 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Thermostable hemolysin DUF2407 PF10302.4 EGO61237.1 - 1.6e-06 28.2 0.2 5.6e-06 26.4 0.2 2.0 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EGO61237.1 - 0.00019 20.7 0.0 0.00039 19.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family CDK2AP PF09806.4 EGO61237.1 - 0.032 14.4 0.6 0.032 14.4 0.4 2.4 2 1 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein adh_short PF00106.20 EGO61238.1 - 2.9e-26 92.3 3.1 4.8e-26 91.6 2.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO61238.1 - 2.5e-24 86.3 0.1 3.5e-24 85.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO61238.1 - 6.8e-13 48.6 1.0 1e-12 48.0 0.7 1.2 1 0 0 1 1 1 1 KR domain malic PF00390.14 EGO61238.1 - 0.16 11.5 0.1 2.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain Eno-Rase_NADH_b PF12242.3 EGO61238.1 - 0.35 10.6 2.5 0.93 9.3 0.3 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase N2227 PF07942.7 EGO61239.1 - 1.6e-108 361.8 0.0 1.9e-108 361.5 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EGO61239.1 - 1.4e-08 34.6 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO61239.1 - 0.0045 17.4 0.0 0.034 14.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO61239.1 - 0.013 15.9 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HEAT_EZ PF13513.1 EGO61241.1 - 6.3e-31 106.0 12.4 2e-14 53.5 0.0 10.4 9 2 4 13 13 12 5 HEAT-like repeat HEAT PF02985.17 EGO61241.1 - 1.5e-24 83.8 19.0 8.5e-06 25.4 0.0 11.4 13 0 0 13 13 12 4 HEAT repeat HEAT_2 PF13646.1 EGO61241.1 - 5.7e-24 84.2 3.0 1.5e-07 31.6 0.0 8.3 5 3 4 9 9 8 5 HEAT repeats Cnd1 PF12717.2 EGO61241.1 - 4e-13 49.5 0.3 0.0065 16.3 0.0 6.2 4 2 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 EGO61241.1 - 7.4e-12 44.7 2.5 3.2e-05 22.8 0.0 5.1 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.2 EGO61241.1 - 1.9e-09 37.7 0.4 0.002 18.4 0.0 5.5 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 EGO61241.1 - 4.6e-08 32.5 3.1 0.055 13.3 0.0 6.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 EGO61241.1 - 1.1e-05 25.2 2.6 0.00093 19.0 0.3 5.0 5 1 1 6 6 5 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EGO61241.1 - 1.7e-05 24.3 0.2 11 5.3 0.0 6.3 4 3 2 7 7 7 1 CLASP N terminal DUF1546 PF07571.8 EGO61241.1 - 0.004 17.2 0.0 2.3 8.3 0.0 3.9 4 1 0 4 4 4 1 Protein of unknown function (DUF1546) HEAT_PBS PF03130.11 EGO61241.1 - 0.015 15.6 1.0 13 6.6 0.0 5.2 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DUF3437 PF11919.3 EGO61241.1 - 0.057 13.1 0.0 6.2 6.6 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Zn_clus PF00172.13 EGO61244.1 - 1e-07 31.7 11.1 1.5e-07 31.1 7.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EGO61244.1 - 8.3e-07 27.9 0.2 8.3e-07 27.9 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Exo_endo_phos PF03372.18 EGO61247.1 - 6.2e-10 39.4 0.2 8.8e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MAP7 PF05672.6 EGO61249.1 - 0.0011 18.4 11.7 0.0011 18.4 8.1 2.6 2 1 0 2 2 2 1 MAP7 (E-MAP-115) family BDV_P40 PF06407.6 EGO61249.1 - 0.16 10.8 0.1 0.27 10.0 0.1 1.3 1 0 0 1 1 1 0 Borna disease virus P40 protein SPRY PF00622.23 EGO61250.1 - 1.4e-18 67.1 0.1 2.4e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 SPRY domain YqgB PF11036.3 EGO61250.1 - 0.1 12.0 0.3 0.27 10.7 0.2 1.6 1 0 0 1 1 1 0 Virulence promoting factor DUF336 PF03928.9 EGO61251.1 - 0.058 13.1 0.1 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF336) SAP PF02037.22 EGO61252.1 - 3e-15 55.2 0.0 4.9e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 EGO61252.1 - 0.021 14.3 1.8 0.12 11.9 0.1 2.5 2 1 0 2 2 2 0 HeH/LEM domain Sterol-sensing PF12349.3 EGO61253.1 - 6.9e-42 142.5 8.5 1.3e-41 141.6 5.9 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EGO61253.1 - 6.1e-13 47.6 4.0 9e-13 47.0 2.8 1.2 1 0 0 1 1 1 1 Patched family WD40 PF00400.27 EGO61253.1 - 0.0011 18.7 0.1 0.0075 16.1 0.1 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Cupin_8 PF13621.1 EGO61257.1 - 1.1e-54 185.5 0.0 1.5e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EGO61257.1 - 6.5e-06 25.6 0.0 0.0025 17.1 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein Spb1_C PF07780.7 EGO61258.1 - 1.9e-74 249.7 39.3 1.9e-74 249.7 27.2 4.3 3 2 1 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.3 EGO61258.1 - 3.8e-57 192.2 11.3 3.8e-57 192.2 7.8 5.1 3 1 2 5 5 5 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 EGO61258.1 - 1e-54 185.2 0.1 3e-54 183.7 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase WD40 PF00400.27 EGO61259.1 - 1.6e-24 84.8 0.8 5.5e-06 26.0 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EGO61259.1 - 0.00016 19.9 0.0 0.0066 14.6 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Met_asp_mut_E PF06368.6 EGO61259.1 - 0.31 9.1 0.0 0.47 8.5 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Sigma70_ner PF04546.8 EGO61261.1 - 4.1 6.9 11.9 0.17 11.4 4.2 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region MKT1_C PF12246.3 EGO61264.1 - 3.6e-08 32.7 0.0 3.8e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication RabGAP-TBC PF00566.13 EGO61265.1 - 8.6e-37 126.6 0.0 1.4e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EGO61265.1 - 1.4e-07 31.0 0.0 0.00053 19.3 0.0 3.3 4 0 0 4 4 4 2 Domain of unknown function (DUF3548) Herpes_capsid PF06112.6 EGO61265.1 - 0.0039 17.2 1.2 0.0091 16.0 0.8 1.6 1 0 0 1 1 1 1 Gammaherpesvirus capsid protein Frag1 PF10277.4 EGO61266.1 - 3.8e-45 154.0 17.5 4.4e-45 153.8 12.1 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3093 PF11292.3 EGO61266.1 - 0.22 11.2 3.3 0.43 10.3 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) Pkinase PF00069.20 EGO61267.1 - 5.1e-63 212.6 0.0 1.8e-62 210.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO61267.1 - 2.2e-31 108.8 0.0 3.4e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO61267.1 - 6.7e-05 21.9 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Sec10 PF07393.6 EGO61268.1 - 1.1e-169 566.0 0.0 8e-169 563.1 0.0 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 EGO61268.1 - 1e-08 34.7 0.7 3.1e-08 33.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGO61268.1 - 1.5e-07 30.8 0.2 3e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 F-box domain Glyco_hydro_63 PF03200.11 EGO61269.1 - 6.5e-245 814.7 0.1 6.7e-244 811.4 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 EGO61269.1 - 4.9e-05 22.2 0.0 9.4e-05 21.2 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.13 EGO61269.1 - 0.0036 15.9 0.1 0.0088 14.7 0.1 1.6 1 0 0 1 1 1 1 Trehalase bZIP_1 PF00170.16 EGO61270.1 - 0.067 13.1 6.0 0.14 12.1 4.1 1.5 1 0 0 1 1 1 0 bZIP transcription factor CAF-1_p150 PF11600.3 EGO61270.1 - 1.7 7.9 15.1 3.4 6.9 7.8 2.6 2 1 1 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal IGR PF09597.5 EGO61271.1 - 1.3e-24 85.8 0.0 2.2e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 IGR protein motif SAM_1 PF00536.25 EGO61271.1 - 0.0078 16.3 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SNF2_N PF00176.18 EGO61272.1 - 2.8e-49 167.5 0.5 7.7e-49 166.0 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EGO61272.1 - 1.3e-08 34.5 12.0 2.6e-08 33.5 8.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGO61272.1 - 7.1e-08 32.0 9.7 1.3e-07 31.1 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO61272.1 - 4.3e-07 29.8 12.1 8.3e-07 28.9 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGO61272.1 - 1.3e-06 27.9 11.2 2.5e-06 27.0 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO61272.1 - 4.6e-06 26.2 10.9 8.3e-06 25.4 7.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EGO61272.1 - 2.7e-05 24.2 7.0 7.4e-05 22.7 4.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 EGO61272.1 - 0.0064 16.0 7.1 0.013 15.0 4.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EGO61272.1 - 0.064 12.9 5.7 0.054 13.2 2.5 2.0 1 1 1 2 2 2 0 RING-type zinc-finger Helicase_C PF00271.26 EGO61272.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-P11 PF03854.9 EGO61272.1 - 0.11 12.0 6.8 0.36 10.3 4.7 1.9 1 1 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.1 EGO61272.1 - 0.12 12.2 10.8 0.24 11.2 7.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EGO61272.1 - 0.19 11.5 4.1 0.47 10.2 2.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EGO61272.1 - 0.22 11.1 7.8 0.11 12.1 3.5 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 EGO61272.1 - 0.75 9.6 5.4 3.5 7.5 3.9 1.9 1 1 0 1 1 1 0 Double zinc ribbon Malic_M PF03949.10 EGO61273.1 - 4.3e-92 308.2 0.0 6.2e-92 307.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EGO61273.1 - 3.3e-72 241.8 0.0 6.2e-72 241.0 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain SNF2_N PF00176.18 EGO61274.1 - 2.6e-64 216.9 0.2 4.6e-64 216.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGO61274.1 - 2.6e-12 46.4 0.0 6.2e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EGO61274.1 - 2.5e-05 23.8 13.4 2.5e-05 23.8 9.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGO61274.1 - 0.0031 17.3 13.6 0.0031 17.3 9.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGO61274.1 - 0.01 15.8 13.2 0.01 15.8 9.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CCD PF07860.6 EGO61274.1 - 0.02 14.3 0.0 0.064 12.7 0.0 1.8 1 0 0 1 1 1 0 WisP family C-Terminal Region AT_hook PF02178.14 EGO61274.1 - 0.079 12.6 6.8 0.37 10.6 4.7 2.3 1 0 0 1 1 1 0 AT hook motif LRR_6 PF13516.1 EGO61275.1 - 1.7e-05 24.4 0.4 1.1 9.5 0.0 7.2 9 0 0 9 9 9 1 Leucine Rich repeat GATA PF00320.22 EGO61275.1 - 0.0043 16.3 0.7 0.0043 16.3 0.5 1.8 2 0 0 2 2 2 1 GATA zinc finger LRR_8 PF13855.1 EGO61275.1 - 0.0084 15.8 6.5 7 6.4 0.0 4.8 3 3 1 4 4 4 2 Leucine rich repeat DZR PF12773.2 EGO61275.1 - 0.05 13.4 0.4 0.36 10.6 0.4 2.3 2 0 0 2 2 2 0 Double zinc ribbon PGA2 PF07543.7 EGO61275.1 - 0.065 13.0 3.1 0.35 10.6 2.7 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 Dicty_REP PF05086.7 EGO61275.1 - 0.8 7.3 4.6 1.2 6.8 3.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LPP20 PF02169.11 EGO61275.1 - 1.5 8.9 7.3 3.7 7.7 5.1 1.6 1 0 0 1 1 1 0 LPP20 lipoprotein MRP-L46 PF11788.3 EGO61277.1 - 0.098 13.3 1.1 0.53 10.9 0.7 1.9 1 1 0 1 1 1 0 39S mitochondrial ribosomal protein L46 DUF1793 PF08760.6 EGO61279.1 - 2.6e-80 268.2 1.3 1.2e-79 266.1 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1793) Meiosis_expr PF15163.1 EGO61279.1 - 0.82 10.0 4.9 0.8 10.1 0.3 2.7 2 0 0 2 2 2 0 Meiosis-expressed SR-25 PF10500.4 EGO61279.1 - 3.6 6.9 5.9 6.5 6.1 4.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3812 PF12757.2 EGO61280.1 - 4.3e-37 126.9 13.8 4.3e-37 126.9 9.5 4.4 4 1 1 5 5 5 1 Protein of unknown function (DUF3812) Aminotran_3 PF00202.16 EGO61280.1 - 0.0038 16.1 2.7 0.0038 16.1 1.9 2.0 2 0 0 2 2 2 1 Aminotransferase class-III WSC PF01822.14 EGO61281.1 - 2.8e-38 129.7 27.5 5e-20 71.2 7.7 3.2 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.18 EGO61281.1 - 7.2e-24 84.5 0.1 1.8e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 Peroxidase GAS2 PF02187.12 EGO61282.1 - 0.00065 19.4 0.1 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Fungal_trans PF04082.13 EGO61284.1 - 1.1e-34 119.5 0.0 1.6e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO61284.1 - 2.1e-06 27.5 10.0 4.2e-06 26.5 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ORC6 PF05460.8 EGO61284.1 - 1.4 7.9 6.8 3.2 6.7 4.7 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FAM176 PF14851.1 EGO61286.1 - 2.1 8.0 8.8 2.1 8.0 6.1 1.0 1 0 0 1 1 1 0 FAM176 family FYDLN_acid PF09538.5 EGO61286.1 - 2.4 8.7 6.6 2.4 8.7 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CRF1 PF10380.4 EGO61286.1 - 2.9 8.2 11.0 3.1 8.1 7.6 1.0 1 0 0 1 1 1 0 Transcription factor CRF1 AIF_C PF14721.1 EGO61286.1 - 3.6 7.8 12.4 3.5 7.8 8.6 1.0 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Rxt3 PF08642.5 EGO61286.1 - 5.1 7.3 8.0 5.2 7.3 5.5 1.1 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Dala_Dala_lig_N PF01820.16 EGO61286.1 - 6.3 7.1 9.1 6.8 7.0 6.3 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus FimP PF09766.4 EGO61286.1 - 7.5 5.5 30.6 7.5 5.5 21.2 1.0 1 0 0 1 1 1 0 Fms-interacting protein BRF1 PF07741.8 EGO61286.1 - 7.6 6.8 15.4 7.6 6.8 10.7 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Gti1_Pac2 PF09729.4 EGO61286.1 - 8.4 6.2 10.8 8.4 6.2 7.5 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family PH_4 PF15404.1 EGO61286.1 - 8.8 5.8 13.4 8.5 5.8 9.3 1.0 1 0 0 1 1 1 0 Pleckstrin homology domain Glyco_hydro_3 PF00933.16 EGO61287.1 - 3.2e-78 262.7 0.1 1.8e-76 256.9 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGO61287.1 - 3.5e-57 193.5 0.0 1.1e-55 188.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGO61287.1 - 5.4e-19 67.8 0.1 9.6e-19 67.1 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.6 EGO61287.1 - 0.051 13.6 0.0 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 CARDB Lipase_3 PF01764.20 EGO61288.1 - 1.7e-40 137.8 0.1 3.2e-40 136.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGO61288.1 - 0.00031 20.5 0.7 0.0077 15.9 0.4 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 EGO61288.1 - 0.00092 18.5 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.15 EGO61288.1 - 0.0081 16.4 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EGO61288.1 - 0.018 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 EGO61288.1 - 0.021 14.7 1.4 0.049 13.5 0.4 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Cutinase PF01083.17 EGO61288.1 - 0.024 14.3 0.7 0.046 13.4 0.0 1.9 2 0 0 2 2 2 0 Cutinase Abhydrolase_3 PF07859.8 EGO61288.1 - 0.035 13.6 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 EGO61288.1 - 0.061 12.6 0.8 0.52 9.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF3650 PF12368.3 EGO61288.1 - 0.066 12.7 0.1 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) Ribosomal_L34 PF00468.12 EGO61289.1 - 7.2e-13 47.9 7.9 1.1e-12 47.3 5.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Peptidase_M48 PF01435.13 EGO61290.1 - 1.4e-50 171.9 0.1 2.6e-50 171.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EGO61290.1 - 0.00073 18.5 0.2 0.0014 17.6 0.1 1.5 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF4538 PF15061.1 EGO61290.1 - 0.05 12.9 0.8 0.14 11.4 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF955 PF06114.8 EGO61290.1 - 0.1 12.3 0.3 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF955) DUF1772 PF08592.6 EGO61290.1 - 0.13 12.0 0.1 0.13 12.0 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) DUF3487 PF11990.3 EGO61291.1 - 0.0042 16.4 0.0 0.0046 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3487) Ish1 PF10281.4 EGO61291.1 - 0.017 15.1 0.1 0.03 14.4 0.1 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Ribosomal_L38e PF01781.13 EGO61292.1 - 8.2e-33 111.9 3.1 1e-32 111.6 2.1 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Dehydratase_hem PF13816.1 EGO61293.1 - 0.043 12.8 0.5 0.57 9.1 0.0 2.0 2 0 0 2 2 2 0 Haem-containing dehydratase GHMP_kinases_N PF00288.21 EGO61294.1 - 1.9e-19 69.4 0.0 4.2e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGO61294.1 - 6e-08 32.7 0.0 1.4e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EGO61294.1 - 0.0044 16.2 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.17 EGO61295.1 - 2.6e-41 137.2 11.1 2.2e-08 33.0 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Val_tRNA-synt_C PF10458.4 EGO61296.1 - 0.16 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm PGA2 PF07543.7 EGO61297.1 - 3.6e-52 175.8 4.4 4.2e-52 175.6 3.0 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 CENP-S PF15630.1 EGO61298.1 - 2e-34 117.5 0.1 2.9e-34 117.1 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EGO61298.1 - 0.00046 19.5 0.0 0.00066 19.0 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-18kDa PF02269.11 EGO61298.1 - 0.013 15.2 0.1 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TAF PF02969.12 EGO61298.1 - 0.013 15.3 0.1 0.12 12.3 0.0 2.2 1 1 1 2 2 2 0 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 EGO61298.1 - 0.016 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EGO61298.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 WD40 PF00400.27 EGO61299.1 - 8.9e-69 225.1 6.8 7.3e-10 38.3 0.0 11.6 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 EGO61299.1 - 2.3e-45 153.7 0.1 3.7e-45 153.0 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EGO61299.1 - 2.9e-08 32.3 1.7 0.0058 14.8 0.0 4.4 3 1 0 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGO61299.1 - 0.0044 15.8 1.4 2.8 6.5 0.0 4.6 5 1 0 5 5 5 1 Nup133 N terminal like Dmrt1 PF12374.3 EGO61301.1 - 1.2 9.4 12.3 4.4 7.7 8.6 2.0 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 Macoilin PF09726.4 EGO61301.1 - 1.4 7.0 11.9 2.1 6.5 8.2 1.2 1 0 0 1 1 1 0 Transmembrane protein LSM PF01423.17 EGO61302.1 - 4.1e-10 39.0 0.4 1.3e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 LSM domain UQ_con PF00179.21 EGO61304.1 - 2.7e-51 172.6 0.0 3.1e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TPR_11 PF13414.1 EGO61305.1 - 4e-10 39.1 1.5 1.2e-08 34.5 0.0 2.7 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EGO61305.1 - 3.1e-06 26.6 2.0 1 9.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGO61305.1 - 8.9e-05 21.9 0.5 3.1 7.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.26 EGO61305.1 - 0.00015 21.4 0.4 0.00072 19.3 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain DnaJ PF00226.26 EGO61305.1 - 0.0042 16.7 0.0 0.011 15.3 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_12 PF13424.1 EGO61305.1 - 3 7.8 7.8 1.5 8.8 0.1 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGO61305.1 - 5.2 7.9 8.5 5.1 8.0 0.7 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Mcp5_PH PF12814.2 EGO61306.1 - 4.4e-47 159.0 0.0 1.2e-46 157.6 0.0 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology ERM PF00769.14 EGO61306.1 - 0.079 12.4 16.4 0.15 11.5 11.3 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ADIP PF11559.3 EGO61306.1 - 0.14 12.0 17.2 0.34 10.8 11.9 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EGO61306.1 - 0.5 10.1 22.4 7.6 6.2 15.3 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein HAUS6_N PF14661.1 EGO61306.1 - 0.9 8.8 8.2 1.7 7.9 5.7 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus CENP-F_leu_zip PF10473.4 EGO61306.1 - 0.94 9.3 20.8 1.6 8.6 14.4 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.14 EGO61306.1 - 4.2 5.1 7.2 7.3 4.3 5.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EGO61306.1 - 9.4 5.1 16.8 16 4.4 11.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 UPF0220 PF05255.6 EGO61309.1 - 0.31 10.2 2.8 3.2 6.9 0.9 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) YrhK PF14145.1 EGO61309.1 - 0.93 9.2 16.2 4.2 7.1 0.1 4.2 4 1 0 4 4 4 0 YrhK-like protein DUF1218 PF06749.7 EGO61309.1 - 1.7 9.1 6.3 1.8 9.1 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Gar1 PF04410.9 EGO61309.1 - 5.8 6.3 10.1 0.55 9.6 3.2 2.0 1 1 1 2 2 2 0 Gar1/Naf1 RNA binding region HAD_2 PF13419.1 EGO61310.1 - 5.5e-21 75.5 0.1 3.4e-20 73.0 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO61310.1 - 3.3e-09 37.4 0.0 4.6e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO61310.1 - 0.0005 19.7 0.2 0.0011 18.6 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like Opy2 PF09463.5 EGO61312.1 - 2.4e-11 43.4 14.6 4.1e-11 42.7 10.1 1.4 1 0 0 1 1 1 1 Opy2 protein Mid2 PF04478.7 EGO61312.1 - 0.024 14.0 0.1 0.055 12.8 0.1 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Syndecan PF01034.15 EGO61312.1 - 0.066 12.8 0.4 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain zf-Apc11 PF12861.2 EGO61312.1 - 0.073 12.9 2.6 0.13 12.0 1.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Chitin_synth_1 PF01644.12 EGO61313.1 - 1.5e-70 236.2 0.0 2.1e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EGO61313.1 - 1.7e-26 91.6 0.1 3.2e-26 90.8 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EGO61313.1 - 4.1e-26 91.4 0.1 1.7e-21 76.2 0.0 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EGO61313.1 - 4.1e-11 42.9 0.1 4.1e-11 42.9 0.0 2.8 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EGO61313.1 - 7.9e-09 35.6 0.0 7.2e-08 32.5 0.0 2.4 3 0 0 3 3 3 1 Glycosyltransferase like family 2 UQ_con PF00179.21 EGO61314.1 - 2e-36 124.4 0.0 2.7e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGO61314.1 - 0.0054 16.4 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B IlvN PF07991.7 EGO61315.1 - 4.3e-46 156.3 0.0 6.7e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EGO61315.1 - 5e-46 156.2 0.0 7.7e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EGO61315.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGO61315.1 - 0.072 13.5 0.3 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.20 EGO61316.1 - 1.6e-63 214.7 0.0 2e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Transglut_core PF01841.14 EGO61316.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily Rep_fac-A_C PF08646.5 EGO61317.1 - 1.6e-57 193.2 2.5 1.8e-55 186.6 0.8 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EGO61317.1 - 6.4e-22 77.2 0.1 1.5e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EGO61317.1 - 2.6e-18 65.6 3.0 2.5e-12 46.4 0.0 4.5 5 0 0 5 5 5 3 OB-fold nucleic acid binding domain DUF753 PF05444.7 EGO61317.1 - 0.033 14.0 1.8 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF753) zf-like PF04071.7 EGO61317.1 - 0.056 13.1 0.2 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain DUF690 PF05108.8 EGO61317.1 - 0.067 11.5 0.0 0.1 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF690) Amidohydro_2 PF04909.9 EGO61318.1 - 1.1e-27 97.2 0.2 1.3e-27 97.0 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase UxaC PF02614.9 EGO61318.1 - 0.02 13.5 0.0 0.03 12.9 0.0 1.2 1 0 0 1 1 1 0 Glucuronate isomerase DUF3099 PF11298.3 EGO61318.1 - 0.027 14.2 1.7 0.028 14.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) Herpes_pp85 PF04637.7 EGO61319.1 - 0.2 9.9 1.2 0.21 9.8 0.8 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Mito_fiss_reg PF05308.6 EGO61319.1 - 0.52 9.6 7.4 0.53 9.6 5.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Cyt-b5 PF00173.23 EGO61320.1 - 2e-21 75.5 0.3 2.3e-21 75.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 EGO61320.1 - 0.094 12.6 0.0 0.31 10.9 0.0 1.8 1 1 1 2 2 2 0 V-ATPase subunit H SUR7 PF06687.7 EGO61322.1 - 1.7e-36 125.8 15.8 2e-36 125.5 10.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EGO61322.1 - 0.0073 16.2 13.7 0.0073 16.2 9.5 1.7 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 alpha-hel2 PF14456.1 EGO61325.1 - 0.01 14.6 1.3 0.015 14.1 0.9 1.1 1 0 0 1 1 1 0 Alpha-helical domain 2 Fer2 PF00111.22 EGO61325.1 - 0.011 15.4 1.0 0.042 13.5 0.1 2.1 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain RXT2_N PF08595.6 EGO61325.1 - 0.23 11.2 1.1 0.38 10.5 0.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 EGO61325.1 - 0.44 10.0 6.0 0.66 9.4 4.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EGO61325.1 - 1.2 9.3 7.9 2.2 8.5 5.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 EGO61325.1 - 1.7 7.8 8.6 3 7.0 6.0 1.4 1 0 0 1 1 1 0 NOA36 protein Prp19_bind PF06991.6 EGO61326.1 - 4.8e-53 180.2 37.8 4.8e-53 180.2 26.2 2.7 2 1 1 3 3 3 1 Splicing factor, Prp19-binding domain Pol_alpha_B_N PF08418.5 EGO61327.1 - 5.2e-69 232.5 0.0 6.8e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EGO61327.1 - 1.6e-47 161.4 0.0 2.1e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CM2 PF03021.9 EGO61327.1 - 0.18 11.3 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 Influenza C virus M2 protein CRAL_TRIO PF00650.15 EGO61328.1 - 4.1e-45 153.1 0.0 5.5e-45 152.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGO61328.1 - 2.9e-10 40.1 0.3 8.2e-10 38.6 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGO61328.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Med3 PF11593.3 EGO61328.1 - 0.45 9.7 4.5 0.73 9.0 3.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Homeobox PF00046.24 EGO61331.1 - 5.2e-20 70.8 4.5 1e-19 69.8 3.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EGO61331.1 - 0.00028 20.5 0.5 0.00069 19.2 0.4 1.6 1 0 0 1 1 1 1 Homeobox KN domain E1-E2_ATPase PF00122.15 EGO61333.1 - 5e-21 74.8 0.1 1.3e-20 73.4 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGO61333.1 - 1.8e-16 61.2 0.0 4.2e-15 56.7 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGO61333.1 - 1e-14 55.1 0.0 4.2e-14 53.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGO61333.1 - 4.4e-11 42.5 0.0 2.2e-10 40.3 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGO61333.1 - 0.00074 19.1 0.1 0.0018 17.8 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGO61333.1 - 0.091 12.9 0.2 0.62 10.2 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ABC_tran PF00005.22 EGO61334.1 - 3.4e-52 176.3 0.0 1.2e-29 103.3 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 EGO61334.1 - 5.3e-44 150.6 20.8 4.6e-22 78.7 5.1 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EGO61334.1 - 2.3e-10 40.0 2.4 0.0011 18.2 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGO61334.1 - 8.3e-09 36.0 0.2 2.1e-05 24.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EGO61334.1 - 1.1e-06 28.8 0.0 0.58 10.0 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGO61334.1 - 4.1e-06 26.9 0.3 0.024 14.6 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EGO61334.1 - 6.9e-06 25.4 0.2 0.073 12.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EGO61334.1 - 1.7e-05 24.3 0.0 0.06 12.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGO61334.1 - 2.7e-05 23.3 0.0 0.046 12.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 EGO61334.1 - 6.4e-05 21.9 0.0 0.32 9.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein IstB_IS21 PF01695.12 EGO61334.1 - 0.00038 19.9 0.0 0.15 11.4 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_10 PF12846.2 EGO61334.1 - 0.00039 19.9 0.0 1.2 8.4 0.0 3.1 3 0 0 3 3 3 2 AAA-like domain MMR_HSR1 PF01926.18 EGO61334.1 - 0.00092 19.1 0.5 0.23 11.4 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EGO61334.1 - 0.0027 16.8 0.1 2 7.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.1 EGO61334.1 - 0.003 17.7 2.0 5.3 7.2 0.0 4.3 4 0 0 4 4 4 1 AAA domain Miro PF08477.8 EGO61334.1 - 0.0057 17.1 0.2 5.9 7.4 0.1 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 EGO61334.1 - 0.0082 16.9 0.0 10 6.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EGO61334.1 - 0.016 14.8 0.5 0.15 11.7 0.0 2.7 4 0 0 4 4 2 0 Archaeal ATPase RNA_helicase PF00910.17 EGO61334.1 - 0.028 14.5 0.4 4.1 7.6 0.0 3.1 3 0 0 3 3 2 0 RNA helicase DUF87 PF01935.12 EGO61334.1 - 0.036 13.8 1.8 0.2 11.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF815 PF05673.8 EGO61334.1 - 0.038 12.9 0.1 4 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EGO61334.1 - 0.038 13.4 0.0 3.7 6.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.10 EGO61334.1 - 0.044 12.4 0.1 0.11 11.1 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATP-synt_ab PF00006.20 EGO61334.1 - 0.053 13.0 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 EGO61334.1 - 0.09 12.6 0.2 1.8 8.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGO61334.1 - 0.14 12.4 1.7 15 5.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.18 EGO61334.1 - 0.16 11.8 2.4 6.6 6.5 0.0 3.6 3 0 0 3 3 3 0 Dynamin family AAA PF00004.24 EGO61334.1 - 0.18 12.0 0.9 8.1 6.6 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Adaptin_binding PF10199.4 EGO61336.1 - 1.8e-24 86.5 13.9 1.8e-24 86.5 9.6 2.6 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Voldacs PF03517.8 EGO61338.1 - 5.4e-24 84.5 0.1 1e-23 83.6 0.1 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Cytomega_gL PF01801.11 EGO61339.1 - 0.12 11.8 0.1 0.12 11.8 0.1 1.0 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L ketoacyl-synt PF00109.21 EGO61342.1 - 2.3e-74 250.1 0.0 5.3e-74 248.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGO61342.1 - 3.5e-52 177.7 0.1 2.1e-51 175.1 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain Thioesterase PF00975.15 EGO61342.1 - 2.9e-43 148.7 0.0 1.9e-42 146.0 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 EGO61342.1 - 3e-35 120.6 0.8 8.8e-35 119.1 0.5 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EGO61342.1 - 1.2e-23 83.1 3.2 4.6e-12 46.0 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EGO61342.1 - 3.5e-15 55.9 0.0 8.1e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 EGO61342.1 - 3.8e-09 36.7 0.1 0.00041 20.3 0.0 3.4 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO61342.1 - 7.6e-07 28.9 0.0 0.061 13.0 0.0 3.3 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EGO61342.1 - 0.003 16.5 0.1 0.01 14.8 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Zn_clus PF00172.13 EGO61344.1 - 2.7e-06 27.1 17.0 2.7e-06 27.1 11.8 1.9 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 EGO61344.1 - 0.00017 21.7 11.6 0.0023 18.1 0.8 3.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGO61344.1 - 0.0015 18.7 2.8 0.0015 18.7 2.0 3.3 3 1 0 3 3 3 2 C2H2-type zinc finger DUF4187 PF13821.1 EGO61344.1 - 0.0062 16.1 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-H2C2_2 PF13465.1 EGO61344.1 - 0.0067 16.6 0.4 0.0067 16.6 0.3 4.4 3 1 0 3 3 3 1 Zinc-finger double domain DUF92 PF01940.11 EGO61347.1 - 6.2e-61 205.4 3.2 9.9e-61 204.7 2.2 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 Pkinase PF00069.20 EGO61348.1 - 1.6e-77 260.1 0.0 2.3e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO61348.1 - 3.6e-38 131.1 0.0 5.7e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EGO61348.1 - 9.2e-17 60.9 0.4 2.2e-16 59.7 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EGO61348.1 - 9.2e-06 24.8 0.0 3.2e-05 23.0 0.0 1.7 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EGO61348.1 - 0.00019 20.8 0.3 0.00038 19.8 0.2 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 EGO61348.1 - 0.0024 16.5 0.1 0.0036 15.9 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EGO61348.1 - 0.048 13.3 1.1 0.27 10.9 0.3 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family MFS_1 PF07690.11 EGO61349.1 - 3e-33 114.9 27.6 3.8e-33 114.6 19.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Hydantoinase_B PF02538.9 EGO61350.1 - 2.5e-168 560.6 0.8 1.9e-161 537.9 0.2 3.3 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EGO61350.1 - 1.1e-93 313.5 0.6 2.1e-93 312.6 0.4 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EGO61350.1 - 9.3e-59 197.8 3.1 9.1e-58 194.6 0.1 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region ADIP PF11559.3 EGO61351.1 - 1.7e-41 141.6 7.0 1.7e-41 141.6 4.9 3.3 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding RRP7 PF12923.2 EGO61353.1 - 1.5e-36 125.2 13.3 1.5e-36 125.2 9.2 2.0 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Ribosomal_L14e PF01929.12 EGO61353.1 - 2.1 8.7 10.9 0.11 12.8 3.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L14 UBN2_2 PF14227.1 EGO61354.1 - 0.13 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF2567 PF10821.3 EGO61355.1 - 0.0097 15.4 0.2 0.72 9.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2567) UBN2_3 PF14244.1 EGO61356.1 - 0.014 14.9 0.0 0.044 13.3 0.0 1.8 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EGO61356.1 - 0.41 10.1 3.4 2 7.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) MOSC PF03473.12 EGO61358.1 - 1.1e-16 60.5 0.0 3.2e-16 59.0 0.0 1.9 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.22 EGO61358.1 - 1.6e-08 34.2 2.2 1.7e-07 30.9 2.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 EGO61358.1 - 8.9e-08 32.6 0.0 2.4e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain 3-alpha PF03475.9 EGO61358.1 - 0.082 12.6 0.6 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 3-alpha domain F-box PF00646.28 EGO61359.1 - 2e-06 27.3 0.8 6.1e-06 25.7 0.5 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EGO61359.1 - 0.00073 19.2 0.5 0.0016 18.0 0.3 1.6 1 0 0 1 1 1 1 F-box-like Peptidase_S24 PF00717.18 EGO61359.1 - 0.091 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase S24-like CLP_protease PF00574.18 EGO61361.1 - 1.6e-67 226.6 0.1 2.1e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Clp protease ILVD_EDD PF00920.16 EGO61362.1 - 5.7e-209 694.8 0.0 6.6e-209 694.6 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family GTP_EFTU_D4 PF14578.1 EGO61362.1 - 0.044 13.4 0.7 0.3 10.7 0.0 2.6 3 0 0 3 3 3 0 Elongation factor Tu domain 4 Kinesin PF00225.18 EGO61364.1 - 1.4e-104 349.4 3.0 1.4e-104 349.4 2.1 2.3 2 0 0 2 2 2 1 Kinesin motor domain Reo_sigmaC PF04582.7 EGO61364.1 - 0.0019 17.4 17.7 0.013 14.6 1.7 3.1 3 1 1 4 4 4 2 Reovirus sigma C capsid protein Apolipoprotein PF01442.13 EGO61364.1 - 1.2 8.5 45.6 1.3 8.5 29.8 2.1 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain WEMBL PF05701.6 EGO61364.1 - 1.8 6.9 58.2 0.051 12.0 35.2 2.0 2 0 0 2 2 2 0 Weak chloroplast movement under blue light AAA_24 PF13479.1 EGO61364.1 - 3.4 7.2 9.0 1.8 8.1 2.6 3.1 3 1 0 3 3 3 0 AAA domain Tropomyosin_1 PF12718.2 EGO61364.1 - 9.4 6.0 69.1 9.1 6.1 16.1 3.6 2 1 1 3 3 3 0 Tropomyosin like Acetyltransf_3 PF13302.1 EGO61365.1 - 3.7e-14 53.0 0.0 6.6e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGO61365.1 - 5.1e-13 48.8 0.1 3e-12 46.3 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EGO61365.1 - 3.4e-07 30.3 0.0 6.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGO61365.1 - 0.00063 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGO61365.1 - 0.038 13.7 0.1 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein PC4 PF02229.11 EGO61366.1 - 2.3e-18 65.1 0.0 4.8e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) PXA PF02194.10 EGO61367.1 - 3.6e-38 130.9 2.3 5.1e-38 130.5 0.0 2.4 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 EGO61367.1 - 6.5e-23 80.9 3.3 1.2e-22 80.0 0.0 3.1 4 0 0 4 4 4 1 Sorting nexin C terminal PX PF00787.19 EGO61367.1 - 7.5e-07 28.9 0.0 7e-06 25.8 0.0 2.4 2 0 0 2 2 2 1 PX domain PmbA_TldD PF01523.11 EGO61368.1 - 0.12 11.5 0.2 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase DNA_pol_E_B PF04042.11 EGO61370.1 - 1e-73 247.0 0.0 1.7e-73 246.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B HET PF06985.6 EGO61371.1 - 4.2e-10 39.9 2.5 4.2e-10 39.9 1.7 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Cu-oxidase_3 PF07732.10 EGO61372.1 - 6.9e-40 135.4 8.6 3.6e-38 129.9 0.2 3.7 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase_2 PF07731.9 EGO61372.1 - 7.1e-39 132.4 6.5 4.5e-36 123.3 0.8 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EGO61372.1 - 3.4e-25 88.7 0.1 9.9e-24 84.0 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase adh_short PF00106.20 EGO61373.1 - 1.3e-16 60.9 0.6 1.9e-16 60.3 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGO61373.1 - 3.9e-07 30.0 0.0 5.6e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGO61373.1 - 3.4e-06 26.8 0.1 5.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGO61373.1 - 2.2e-05 24.5 0.1 6.4e-05 23.0 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EGO61373.1 - 8.8e-05 21.7 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 EGO61373.1 - 0.0058 15.5 0.1 0.0099 14.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EGO61373.1 - 0.01 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RRM_3 PF08777.6 EGO61373.1 - 0.053 13.3 0.2 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 RNA binding motif Eno-Rase_NADH_b PF12242.3 EGO61373.1 - 0.07 12.9 0.6 0.23 11.2 0.0 2.2 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_binding_3 PF01494.14 EGO61374.1 - 1.1e-75 254.9 0.2 6.8e-75 252.3 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGO61374.1 - 0.00042 19.3 0.2 0.0012 17.8 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO61374.1 - 0.0013 18.8 0.1 0.015 15.4 0.0 2.6 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGO61374.1 - 0.0018 18.1 0.1 0.011 15.5 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EGO61374.1 - 0.0039 16.0 0.0 0.018 13.8 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase 3HCDH_N PF02737.13 EGO61374.1 - 0.0044 16.7 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EGO61374.1 - 0.0059 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 EGO61374.1 - 0.0072 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_2 PF00890.19 EGO61374.1 - 0.0077 15.1 0.1 0.018 13.9 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EGO61374.1 - 0.01 14.7 0.1 0.049 12.5 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EGO61374.1 - 0.021 14.8 0.0 0.065 13.2 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 EGO61374.1 - 0.023 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 EGO61374.1 - 0.059 12.4 0.1 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 EGO61374.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 EGO61374.1 - 0.073 13.5 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3680 PF12441.3 EGO61374.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3680) HET PF06985.6 EGO61376.1 - 3.6e-29 101.6 0.4 3.6e-29 101.6 0.3 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF4175 PF13779.1 EGO61376.1 - 0.52 7.9 5.7 0.74 7.4 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CMD PF02627.15 EGO61377.1 - 1e-11 44.5 0.0 3.3e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family BRCA2 PF00634.13 EGO61377.1 - 0.029 13.6 0.1 0.048 12.9 0.1 1.3 1 0 0 1 1 1 0 BRCA2 repeat APH PF01636.18 EGO61378.1 - 3.9e-09 36.5 0.5 0.0043 16.8 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EGO61378.1 - 9.4e-09 34.6 0.8 2.4e-07 30.0 0.6 2.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EGO61378.1 - 8.9e-08 31.5 0.0 1.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO61378.1 - 0.00022 20.3 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGO61378.1 - 0.00039 19.8 0.2 0.0027 17.0 0.0 2.3 2 1 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EGO61378.1 - 0.043 13.3 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 EGO61378.1 - 0.074 12.1 0.0 0.35 9.9 0.0 1.8 2 0 0 2 2 2 0 Ecdysteroid kinase Aldo_ket_red PF00248.16 EGO61379.1 - 2.9e-10 39.4 0.0 5.2e-10 38.6 0.0 1.4 2 0 0 2 2 2 1 Aldo/keto reductase family Clat_adaptor_s PF01217.15 EGO61380.1 - 4.9e-52 175.4 1.3 5.7e-52 175.2 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.5 EGO61382.1 - 1.6e-67 226.8 0.0 2.7e-67 226.0 0.0 1.4 1 0 0 1 1 1 1 Maf1 regulator HAUS6_N PF14661.1 EGO61382.1 - 0.044 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF1694 PF07997.6 EGO61382.1 - 0.17 11.8 0.0 0.97 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1694) NOA36 PF06524.7 EGO61382.1 - 4.4 6.4 15.7 6.3 5.9 10.9 1.2 1 0 0 1 1 1 0 NOA36 protein DUF1712 PF08217.6 EGO61384.1 - 2.5e-12 45.8 0.0 5.4e-09 34.8 0.0 3.2 3 0 0 3 3 3 3 Fungal domain of unknown function (DUF1712) PP2C PF00481.16 EGO61385.1 - 4.4e-83 278.5 0.0 7.9e-83 277.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EGO61385.1 - 0.00057 19.3 0.0 0.0016 17.9 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C He_PIG PF05345.7 EGO61386.1 - 2.6e-15 56.1 16.8 2.7e-05 24.1 0.9 6.9 6 2 0 6 6 6 4 Putative Ig domain Methyltransf_16 PF10294.4 EGO61387.1 - 2.2e-46 157.4 0.0 2.7e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EGO61387.1 - 0.0082 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO61387.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF1347 PF07079.6 EGO61387.1 - 0.15 10.2 0.0 0.19 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1347) MTS PF05175.9 EGO61387.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DPBB_1 PF03330.13 EGO61388.1 - 0.0016 18.4 0.4 0.0016 18.4 0.3 2.0 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pex24p PF06398.6 EGO61389.1 - 5.9e-06 25.3 3.2 1.5e-05 23.9 2.2 1.7 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3609 PF12259.3 EGO61389.1 - 0.062 11.9 0.1 0.093 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Phage_Gp23 PF10669.4 EGO61389.1 - 0.23 11.5 2.0 0.83 9.7 1.4 1.9 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF883 PF05957.8 EGO61390.1 - 0.44 10.9 4.2 3.8 7.9 2.3 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) HTH_22 PF13309.1 EGO61391.1 - 0.0046 16.6 0.0 0.023 14.4 0.0 2.2 1 0 0 1 1 1 1 HTH domain Oxysterol_BP PF01237.13 EGO61392.1 - 9.9e-108 359.7 0.0 1.8e-107 358.9 0.0 1.4 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EGO61392.1 - 5.9e-39 132.0 0.3 1e-37 128.0 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EGO61392.1 - 0.00017 21.7 0.0 0.00058 20.0 0.0 2.0 2 0 0 2 2 2 1 PH domain GOLD_2 PF13897.1 EGO61392.1 - 0.0074 16.5 0.0 0.0074 16.5 0.0 1.9 2 0 0 2 2 2 1 Golgi-dynamics membrane-trafficking PH_11 PF15413.1 EGO61392.1 - 0.071 13.3 0.1 0.23 11.7 0.1 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain SH2_2 PF14633.1 EGO61393.1 - 3.1e-86 288.0 0.2 1.1e-85 286.1 0.2 2.1 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 EGO61393.1 - 1.5e-36 124.9 5.6 1.5e-36 124.9 3.9 4.1 4 0 0 4 4 4 1 Death-like domain of SPT6 HHH_7 PF14635.1 EGO61393.1 - 3.3e-28 97.8 0.0 8e-28 96.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EGO61393.1 - 6.5e-28 97.1 0.0 2.1e-27 95.5 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 EGO61393.1 - 6e-22 77.6 32.7 6e-22 77.6 22.7 5.7 5 0 0 5 5 5 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EGO61393.1 - 1.6e-17 63.6 1.0 1.6e-17 63.6 0.7 3.2 4 1 0 4 4 4 1 Helix-turn-helix DNA-binding domain of SPT6 S1 PF00575.18 EGO61393.1 - 3e-06 27.2 0.5 7.6e-06 25.9 0.3 1.8 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.19 EGO61393.1 - 5.6e-06 26.0 0.0 1.5e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 EGO61393.1 - 0.00037 20.3 0.0 0.0015 18.4 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif Pkinase PF00069.20 EGO61395.1 - 6e-62 209.1 0.0 7.8e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGO61395.1 - 4e-40 137.5 0.0 5.3e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGO61395.1 - 3.3e-05 23.0 0.0 5.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGO61395.1 - 0.076 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 EGO61395.1 - 0.1 11.9 0.2 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.15 EGO61395.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase HAD_2 PF13419.1 EGO61396.1 - 9.7e-12 45.4 0.0 4.2e-07 30.3 0.0 3.1 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGO61396.1 - 4e-07 30.6 2.0 0.018 15.4 0.4 3.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGO61396.1 - 5.6e-07 29.9 0.0 1.1e-06 28.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGO61396.1 - 7.1e-07 28.8 2.4 2.4e-06 27.1 1.7 2.0 1 1 0 1 1 1 1 HAD-hyrolase-like PGP_phosphatase PF09419.5 EGO61396.1 - 0.042 13.2 0.0 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase FUSC_2 PF13515.1 EGO61397.1 - 5.5e-24 84.5 8.9 5.5e-24 84.5 6.1 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC-like PF12805.2 EGO61397.1 - 0.0027 16.7 1.5 0.89 8.4 0.3 2.8 2 0 0 2 2 2 2 FUSC-like inner membrane protein yccS DUF2421 PF10334.4 EGO61397.1 - 0.018 14.6 0.1 0.13 11.8 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2421) ALMT PF11744.3 EGO61397.1 - 0.12 11.0 17.9 0.25 9.9 2.2 4.6 5 1 0 5 5 5 0 Aluminium activated malate transporter Response_reg PF00072.19 EGO61398.1 - 3.4e-28 97.8 0.2 6.3e-28 97.0 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EGO61398.1 - 2e-27 95.1 0.0 4.4e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGO61398.1 - 3.7e-14 52.4 0.0 8.3e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EGO61398.1 - 0.0007 19.7 2.8 0.051 13.7 0.0 3.4 3 0 0 3 3 3 1 HAMP domain Dicty_REP PF05086.7 EGO61399.1 - 9.3 3.8 4.8 12 3.4 3.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ORMDL PF04061.9 EGO61400.1 - 1.4e-60 202.7 4.4 1.7e-60 202.4 3.0 1.0 1 0 0 1 1 1 1 ORMDL family Trep_Strep PF09605.5 EGO61400.1 - 0.54 9.9 4.7 0.41 10.3 0.8 1.9 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) zf-C2H2_4 PF13894.1 EGO61404.1 - 1.2e-05 25.3 7.5 0.41 11.1 1.1 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO61404.1 - 0.0019 18.4 8.6 0.52 10.7 1.1 3.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type TMF_DNA_bd PF12329.3 EGO61404.1 - 0.024 14.4 7.7 0.065 13.0 5.3 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Herpes_BLRF2 PF05812.7 EGO61404.1 - 0.035 13.9 3.4 0.11 12.2 2.3 1.8 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein HALZ PF02183.13 EGO61404.1 - 0.12 12.0 5.6 0.059 13.0 2.0 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.10 EGO61404.1 - 0.85 9.1 4.3 2.6 7.6 3.0 1.8 1 0 0 1 1 1 0 Septum formation initiator Mnd1 PF03962.10 EGO61404.1 - 1.1 8.9 6.7 0.55 9.8 1.5 2.1 2 0 0 2 2 2 0 Mnd1 family Syntaxin_2 PF14523.1 EGO61404.1 - 1.1 9.3 10.1 0.1 12.6 3.2 2.1 2 0 0 2 2 2 0 Syntaxin-like protein bZIP_2 PF07716.10 EGO61404.1 - 4.8 7.0 10.5 3 7.7 5.3 2.2 2 0 0 2 2 2 0 Basic region leucine zipper APG6 PF04111.7 EGO61404.1 - 8.7 5.2 10.1 0.085 11.8 1.4 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 Lipoxygenase PF00305.14 EGO61406.1 - 6.4e-62 209.5 2.0 1.6e-61 208.2 1.4 1.6 1 1 0 1 1 1 1 Lipoxygenase HET PF06985.6 EGO61407.1 - 6e-27 94.5 0.0 6e-27 94.5 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Cation_efflux PF01545.16 EGO61408.1 - 0.0095 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Cation efflux family Glyco_hydro_35 PF01301.14 EGO61409.1 - 1.7e-90 303.6 0.1 2.4e-90 303.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EGO61409.1 - 3.8e-60 202.3 2.8 7.2e-60 201.4 1.9 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EGO61409.1 - 7.9e-42 142.0 14.2 1.1e-23 83.6 1.8 3.6 3 1 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EGO61409.1 - 4.3e-26 90.1 1.3 9.2e-26 89.0 0.9 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 EGO61409.1 - 0.00028 20.1 0.0 0.00053 19.2 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.19 EGO61409.1 - 0.2 10.9 0.0 0.86 8.8 0.0 1.8 1 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Methyltransf_12 PF08242.7 EGO61410.1 - 0.0015 18.9 0.0 0.0035 17.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO61410.1 - 0.0023 18.3 0.0 0.0058 17.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO61410.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO61410.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Xan_ur_permease PF00860.15 EGO61411.1 - 4.1e-25 88.0 23.0 2e-24 85.8 15.3 2.1 1 1 0 1 1 1 1 Permease family Sulfate_transp PF00916.15 EGO61411.1 - 0.0023 16.9 8.4 0.0068 15.4 4.6 2.4 1 1 0 1 1 1 1 Sulfate transporter family Dicty_CAR PF05462.6 EGO61412.1 - 1.4e-10 40.6 5.9 1.4e-10 40.6 4.1 1.7 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 EGO61412.1 - 4.4e-08 32.9 5.9 7.3e-08 32.2 4.1 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EGO61412.1 - 1.3e-05 24.4 2.4 1.9e-05 23.9 1.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) zf-C2H2_4 PF13894.1 EGO61414.1 - 9.6e-06 25.5 69.4 0.00094 19.3 2.1 8.6 8 1 0 8 8 8 5 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO61414.1 - 0.00012 22.2 13.0 0.0021 18.2 4.2 7.9 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EGO61414.1 - 8.3 6.6 40.2 1.6 8.9 2.3 6.5 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EGO61417.1 - 0.0064 16.7 12.9 0.17 12.2 0.1 4.6 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EGO61417.1 - 0.24 11.8 8.3 19 5.8 0.1 4.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-RING_2 PF13639.1 EGO61422.1 - 4.4e-12 45.6 5.2 8.8e-12 44.6 3.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGO61422.1 - 1.2e-11 44.5 2.0 2.4e-11 43.5 1.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGO61422.1 - 4e-08 32.8 3.9 9.1e-08 31.6 2.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGO61422.1 - 4.1e-07 29.6 1.4 8.2e-07 28.6 0.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGO61422.1 - 5.7e-06 25.8 3.4 1.2e-05 24.8 2.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGO61422.1 - 1.2e-05 25.2 3.7 4.3e-05 23.4 2.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGO61422.1 - 0.00012 21.8 1.3 0.00027 20.7 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGO61422.1 - 0.0011 18.5 2.6 0.0026 17.4 1.4 1.9 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EGO61422.1 - 0.0043 16.5 0.2 0.0093 15.4 0.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 FANCL_C PF11793.3 EGO61422.1 - 0.67 9.9 3.5 3.1 7.8 2.5 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EGO61422.1 - 0.68 9.5 3.7 1.8 8.2 2.6 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EGO61422.1 - 2.1 8.4 5.8 6.4 6.9 4.0 1.8 1 1 0 1 1 1 0 RING-variant domain NmrA PF05368.8 EGO61424.1 - 9.6e-07 28.2 0.0 1.4e-05 24.4 0.0 2.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGO61424.1 - 0.0055 16.7 0.0 0.015 15.2 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EGO61424.1 - 0.053 12.4 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase CsbD PF05532.7 EGO61425.1 - 3e-18 65.2 28.1 2.9e-08 33.2 5.7 3.3 2 1 1 3 3 3 3 CsbD-like DUF4540 PF15073.1 EGO61425.1 - 0.14 12.7 0.1 0.21 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4540) Aminotran_5 PF00266.14 EGO61426.1 - 4.6e-96 321.7 0.0 6.1e-96 321.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGO61426.1 - 8e-09 35.0 0.0 1.3e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EGO61426.1 - 2.4e-06 26.8 0.0 7.2e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EGO61426.1 - 0.0036 15.8 0.1 0.0054 15.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain BAR PF03114.13 EGO61427.1 - 1.5e-69 234.0 8.7 2e-69 233.5 6.0 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EGO61427.1 - 2.5e-14 52.3 0.0 5.4e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGO61427.1 - 9.5e-11 41.1 0.0 1.8e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGO61427.1 - 2e-08 33.5 0.1 6.4e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain DUF2365 PF10157.4 EGO61427.1 - 0.026 14.4 0.7 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) Sec20 PF03908.8 EGO61427.1 - 0.099 12.3 0.8 6.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Sec20 Vps5 PF09325.5 EGO61427.1 - 0.28 10.3 9.4 4 6.6 3.2 2.2 2 0 0 2 2 2 0 Vps5 C terminal like MARVEL PF01284.18 EGO61429.1 - 4e-26 91.5 14.3 4.7e-26 91.3 9.9 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF1673 PF07895.6 EGO61429.1 - 0.16 11.4 2.4 1.8 8.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) Claudin_2 PF13903.1 EGO61429.1 - 0.25 10.9 14.2 5.9 6.5 0.0 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction eIF-5_eIF-2B PF01873.12 EGO61431.1 - 2.3e-44 150.0 0.2 4.3e-44 149.1 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EGO61431.1 - 0.062 13.6 0.1 0.22 11.8 0.0 2.0 1 0 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_6 PF14599.1 EGO61431.1 - 0.12 12.1 0.4 21 5.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon DNA_RNApol_7kD PF03604.8 EGO61431.1 - 0.17 11.3 1.5 0.44 10.0 1.1 1.7 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Arc_trans_TRASH PF08394.5 EGO61431.1 - 2.6 8.2 7.5 1.8 8.8 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain DAO PF01266.19 EGO61432.1 - 1.9e-60 204.6 4.4 1e-59 202.2 3.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO61432.1 - 0.0015 18.6 0.0 0.85 9.6 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGO61432.1 - 0.031 14.3 2.8 0.063 13.3 1.4 1.9 1 1 1 2 2 2 0 NAD(P)-binding Rossmann-like domain A_deaminase PF00962.17 EGO61433.1 - 1e-42 146.2 0.0 5.1e-42 143.9 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase PNGaseA PF12222.3 EGO61434.1 - 2.6e-131 438.4 5.4 3.6e-131 437.9 3.7 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1279 PF06916.8 EGO61435.1 - 5.6e-29 100.2 0.1 1e-28 99.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) AIM24 PF01987.12 EGO61436.1 - 1.9e-52 177.8 0.1 2.3e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DNA_primase_lrg PF04104.9 EGO61437.1 - 2.3e-81 272.8 0.0 3.4e-81 272.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Methyltransf_12 PF08242.7 EGO61438.1 - 2.6e-15 56.7 0.1 1e-14 54.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO61438.1 - 2.2e-11 44.1 0.1 5.5e-11 42.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGO61438.1 - 8.4e-10 38.9 0.0 3e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO61438.1 - 1.3e-09 38.0 0.0 1.3e-09 38.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO61438.1 - 1.5e-09 37.6 0.0 3.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO61438.1 - 3.7e-08 33.9 0.0 1.2e-07 32.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO61438.1 - 5.9e-08 32.1 0.0 9.2e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGO61438.1 - 0.00029 20.8 0.0 0.00053 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO61438.1 - 0.0016 17.8 0.0 0.0035 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 EGO61438.1 - 0.01 16.6 0.0 0.032 15.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EGO61438.1 - 0.012 15.3 0.0 0.044 13.4 0.0 1.9 1 1 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_16 PF10294.4 EGO61438.1 - 0.022 14.2 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF3419 PF11899.3 EGO61438.1 - 0.022 13.4 0.0 0.038 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) FmrO PF07091.6 EGO61438.1 - 0.061 12.3 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TehB PF03848.9 EGO61438.1 - 0.12 11.4 0.0 0.28 10.3 0.0 1.6 2 0 0 2 2 2 0 Tellurite resistance protein TehB CN_hydrolase PF00795.17 EGO61439.1 - 5.9e-27 94.2 0.0 9.1e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EGO61439.1 - 1.5e-20 73.1 0.0 5e-20 71.4 0.0 1.8 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 EGO61439.1 - 0.065 12.7 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 Asparagine synthase Polyketide_cyc PF03364.15 EGO61440.1 - 6.5e-39 132.8 0.0 9.4e-39 132.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Se-cys_synth_N PF12390.3 EGO61441.1 - 0.091 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Selenocysteine synthase N terminal TPR_11 PF13414.1 EGO61443.1 - 2.6e-10 39.7 11.5 3.1e-08 33.1 0.4 4.2 2 1 2 5 5 5 2 TPR repeat TPR_14 PF13428.1 EGO61443.1 - 1.4e-09 37.7 13.4 0.00051 20.4 0.2 5.8 3 1 3 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGO61443.1 - 3.2e-08 32.8 12.4 2.9e-06 26.7 0.2 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO61443.1 - 1.2e-07 32.2 12.6 9.7e-05 22.9 0.1 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGO61443.1 - 6.6e-07 29.5 14.3 1.9e-05 24.9 0.1 4.3 4 2 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGO61443.1 - 1.8e-06 27.6 1.1 0.0056 16.7 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGO61443.1 - 6.3e-06 25.6 1.0 0.00019 20.9 0.1 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGO61443.1 - 3.7e-05 23.1 0.5 0.00049 19.6 0.1 3.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGO61443.1 - 0.00068 19.2 3.4 0.19 11.5 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGO61443.1 - 0.00073 19.4 6.1 0.016 15.0 1.0 3.5 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGO61443.1 - 0.0017 18.1 0.2 0.0017 18.1 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR_3 PF13812.1 EGO61443.1 - 0.0025 17.9 0.3 0.025 14.8 0.0 2.8 3 0 0 3 3 2 1 Pentatricopeptide repeat domain ChAPs PF09295.5 EGO61443.1 - 0.018 13.8 0.1 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Vps39_1 PF10366.4 EGO61443.1 - 0.024 14.6 0.3 8.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_20 PF14561.1 EGO61443.1 - 0.024 14.7 2.7 0.14 12.3 0.0 3.1 2 1 0 3 3 3 0 Tetratricopeptide repeat DUF3366 PF11846.3 EGO61443.1 - 0.051 13.4 0.1 0.78 9.5 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3366) Apc3 PF12895.2 EGO61443.1 - 0.13 12.4 0.9 0.39 10.8 0.0 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EGO61443.1 - 8.3 7.1 10.5 15 6.3 0.1 4.9 6 1 0 6 6 4 0 Tetratricopeptide repeat Adaptin_N PF01602.15 EGO61444.1 - 2.6e-86 290.0 0.7 3.6e-86 289.5 0.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region LCCL PF03815.14 EGO61445.1 - 3.4e-19 68.6 0.1 6.4e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 LCCL domain TGT PF01702.13 EGO61446.1 - 5.8e-39 133.7 0.0 7.4e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Abhydrolase_2 PF02230.11 EGO61447.1 - 8.3e-14 51.5 0.0 3.3e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGO61447.1 - 8.2e-08 32.1 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO61447.1 - 3.4e-06 27.1 0.0 0.036 13.9 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 EGO61447.1 - 0.0034 16.8 0.0 0.0075 15.7 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) MFS_1 PF07690.11 EGO61448.1 - 6.9e-32 110.5 33.5 6.9e-32 110.5 23.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EGO61448.1 - 0.011 15.2 2.2 0.011 15.2 1.6 2.3 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 PALP PF00291.20 EGO61449.1 - 1.5e-32 113.1 0.1 1.8e-32 112.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme APG5 PF04106.7 EGO61451.1 - 5.8e-25 87.9 0.0 5.7e-24 84.6 0.0 2.2 1 1 0 2 2 2 1 Autophagy protein Apg5 Ribonuclease PF00545.15 EGO61451.1 - 0.13 12.3 0.6 0.35 10.9 0.4 1.7 1 1 0 1 1 1 0 ribonuclease Zn_clus PF00172.13 EGO61452.1 - 1.5e-06 28.0 13.4 2.2e-06 27.4 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EGO61458.1 - 6.2e-09 35.3 4.0 0.0094 15.8 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 EGO61458.1 - 0.037 12.1 0.0 0.052 11.6 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PhzC-PhzF PF02567.11 EGO61460.1 - 1.8e-23 83.1 0.0 2.3e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Peptidase_S8 PF00082.17 EGO61462.1 - 2.7e-10 39.8 0.0 6.1e-10 38.7 0.0 1.5 1 1 0 1 1 1 1 Subtilase family Pkinase PF00069.20 EGO61465.1 - 6.3e-06 25.5 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGO61465.1 - 0.0006 19.6 0.2 0.0029 17.3 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF601 PF04642.7 EGO61465.1 - 0.82 8.9 4.6 1.3 8.3 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Profilin PF00235.14 EGO61466.1 - 1.9e-31 108.6 0.2 2.2e-31 108.5 0.1 1.0 1 0 0 1 1 1 1 Profilin MAPEG PF01124.13 EGO61467.1 - 1.7e-22 79.4 0.6 1.9e-22 79.2 0.4 1.0 1 0 0 1 1 1 1 MAPEG family Excalibur PF05901.6 EGO61468.1 - 0.16 12.3 13.3 33 4.9 0.2 5.3 5 0 0 5 5 5 0 Excalibur calcium-binding domain MARVEL PF01284.18 EGO61469.1 - 3.6e-19 69.0 13.5 4.3e-19 68.7 9.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2976 PF11190.3 EGO61469.1 - 0.016 14.7 3.5 0.018 14.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) PRA1 PF03208.14 EGO61469.1 - 5.3 6.3 12.1 2 7.7 5.5 2.2 2 1 0 2 2 2 0 PRA1 family protein DUF202 PF02656.10 EGO61469.1 - 6.3 7.0 7.8 4.6e+02 1.1 5.4 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF4449 PF14613.1 EGO61470.1 - 0.00052 19.9 0.1 0.00052 19.9 0.1 3.1 5 0 0 5 5 5 1 Protein of unknown function (DUF4449) LBP_BPI_CETP PF01273.20 EGO61470.1 - 0.0024 17.2 0.0 0.0054 16.0 0.0 1.5 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Tricorn_C1 PF14684.1 EGO61470.1 - 0.029 14.2 1.0 0.3 11.0 0.1 2.9 3 1 1 4 4 4 0 Tricorn protease C1 domain Patatin PF01734.17 EGO61471.1 - 1.7e-25 90.1 0.0 3.1e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Fungal_trans_2 PF11951.3 EGO61473.1 - 1.1e-06 27.4 0.0 2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EGO61474.1 - 2.3e-07 30.6 14.5 0.062 13.6 0.1 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger Peptidase_C14 PF00656.17 EGO61474.1 - 0.0056 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Caspase domain zf-TRAF PF02176.13 EGO61474.1 - 0.43 10.9 6.1 0.067 13.5 1.0 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger Glyco_hydro_31 PF01055.21 EGO61475.1 - 5e-177 589.1 1.0 6.4e-177 588.7 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGO61475.1 - 4.9e-12 45.5 2.2 1.4e-10 40.8 1.2 2.9 2 0 0 2 2 2 1 Galactose mutarotase-like GST_C_3 PF14497.1 EGO61478.1 - 1.5e-09 38.1 0.0 2.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGO61478.1 - 3e-07 30.3 0.1 5.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGO61478.1 - 0.00036 20.6 0.0 0.0023 18.0 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGO61478.1 - 0.0051 16.6 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2183 PF09949.4 EGO61479.1 - 1.7e-31 108.0 0.0 3.1e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) BCL_N PF04714.8 EGO61481.1 - 0.088 12.3 0.5 0.088 12.3 0.4 2.2 3 0 0 3 3 3 0 BCL7, N-terminal conserver region Spore_YtfJ PF09579.5 EGO61487.1 - 3.7 7.4 12.2 0.095 12.5 3.7 2.0 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) An_peroxidase PF03098.10 EGO61490.1 - 5.4e-129 430.9 0.0 3.6e-127 424.9 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase Amidohydro_1 PF01979.15 EGO61490.1 - 8.5e-35 120.9 0.0 1.5e-34 120.1 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EGO61490.1 - 7.9e-14 52.3 0.0 2.6e-13 50.6 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EGO61490.1 - 7.8e-10 38.4 0.0 1.8e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGO61490.1 - 0.00016 21.0 1.3 0.0011 18.3 0.3 2.3 1 1 0 1 1 1 1 Amidohydrolase family Retrotrans_gag PF03732.12 EGO61491.1 - 0.0097 15.9 0.1 2.3 8.3 0.0 2.4 2 0 0 2 2 2 2 Retrotransposon gag protein UBN2_2 PF14227.1 EGO61491.1 - 0.026 14.0 0.0 0.07 12.6 0.0 1.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Glyco_hydro_16 PF00722.16 EGO61492.1 - 9.4e-41 139.1 0.8 1.7e-40 138.2 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Adap_comp_sub PF00928.16 EGO61493.1 - 3e-87 292.0 0.0 4e-87 291.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGO61493.1 - 4.4e-05 23.2 0.2 8e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 EGO61493.1 - 0.021 14.6 0.1 0.048 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) Methyltransf_3 PF01596.12 EGO61494.1 - 3.3e-31 107.9 0.0 4.2e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EGO61494.1 - 8.7e-12 45.8 0.0 1.3e-11 45.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO61494.1 - 2.8e-08 34.3 0.0 4.8e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO61494.1 - 1e-05 25.1 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGO61494.1 - 8.9e-05 21.9 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGO61494.1 - 0.00013 22.0 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF633 PF04816.7 EGO61494.1 - 0.00025 20.4 0.0 0.00038 19.8 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF633) CmcI PF04989.7 EGO61494.1 - 0.00032 20.0 0.0 0.00046 19.5 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase UPF0020 PF01170.13 EGO61494.1 - 0.00072 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.5 EGO61494.1 - 0.0052 16.3 0.0 0.0081 15.7 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 EGO61494.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2381 PF09544.5 EGO61494.1 - 0.022 13.8 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) Methyltransf_4 PF02390.12 EGO61494.1 - 0.053 12.5 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Met_10 PF02475.11 EGO61494.1 - 0.091 12.3 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Bestrophin PF01062.16 EGO61496.1 - 1.8e-42 145.2 0.8 1.1e-24 86.9 0.1 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel GP41 PF00517.12 EGO61496.1 - 0.046 13.2 0.8 0.11 11.9 0.5 1.6 1 0 0 1 1 1 0 Retroviral envelope protein MFS_1 PF07690.11 EGO61497.1 - 4.1e-32 111.2 32.0 4.1e-32 111.2 22.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Halogen_Hydrol PF10112.4 EGO61497.1 - 3.4 7.0 4.0 6.8 6.0 0.5 2.6 2 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein UNC-93 PF05978.11 EGO61497.1 - 3.9 6.9 13.9 1.1 8.7 3.4 2.6 2 1 1 3 3 3 0 Ion channel regulatory protein UNC-93 PLDc_2 PF13091.1 EGO61498.1 - 3.9e-20 71.8 0.0 4.5e-14 52.2 0.0 2.7 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EGO61498.1 - 0.00043 19.9 0.1 0.12 12.1 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Glyco_hydro_6 PF01341.12 EGO61500.1 - 1.9e-108 362.4 1.7 2.6e-108 361.9 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 EGO61500.1 - 5.9e-12 45.0 11.3 1.5e-11 43.7 7.9 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Yeast-kill-tox PF09207.6 EGO61500.1 - 0.034 14.5 7.7 0.12 12.7 3.7 2.6 2 0 0 2 2 2 0 Yeast killer toxin ThuA PF06283.6 EGO61502.1 - 3.5e-64 216.4 0.0 4e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation Hydrolase_like PF13242.1 EGO61503.1 - 0.0036 16.9 0.0 0.0072 16.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Tex_N PF09371.5 EGO61503.1 - 0.039 13.2 0.0 0.087 12.1 0.0 1.4 1 1 0 1 1 1 0 Tex-like protein N-terminal domain DUF1772 PF08592.6 EGO61505.1 - 9.9e-21 73.9 0.0 1.2e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) ETRAMP PF09716.5 EGO61505.1 - 0.006 16.5 0.3 0.01 15.7 0.2 1.4 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) L1R_F9L PF02442.12 EGO61505.1 - 0.062 12.7 0.0 0.084 12.3 0.0 1.1 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses DUF1195 PF06708.6 EGO61505.1 - 0.11 11.9 0.2 0.15 11.4 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1195) SR-25 PF10500.4 EGO61505.1 - 0.28 10.6 9.8 0.39 10.1 6.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Opi1 PF08618.5 EGO61506.1 - 3.8e-127 424.7 9.6 5.9e-108 361.5 4.7 3.0 1 1 1 2 2 2 2 Transcription factor Opi1 Perilipin PF03036.11 EGO61506.1 - 0.026 13.3 5.0 0.037 12.8 0.0 2.3 2 1 0 2 2 2 0 Perilipin family Adap_comp_sub PF00928.16 EGO61509.1 - 1.3e-90 303.0 0.0 1.7e-90 302.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGO61509.1 - 4.8e-09 36.0 0.2 7.9e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Prion PF00377.13 EGO61510.1 - 0.0081 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Prion/Doppel alpha-helical domain Abhydrolase_3 PF07859.8 EGO61511.1 - 1.8e-18 66.9 0.0 9.8e-17 61.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGO61511.1 - 1.7e-10 40.4 0.0 7e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGO61511.1 - 1.8e-10 40.7 0.0 3.4e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGO61511.1 - 1.3e-08 35.0 0.5 2.8e-08 33.9 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EGO61511.1 - 6.6e-06 25.1 0.0 1.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.2 EGO61511.1 - 0.0038 16.1 0.0 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EGO61512.1 - 9e-27 94.4 0.0 1e-26 94.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGO61512.1 - 1.8e-12 47.2 0.0 1.2e-11 44.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO61512.1 - 4.5e-11 42.6 0.0 8.2e-11 41.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EGO61512.1 - 0.00021 20.6 0.0 0.0014 17.9 0.0 2.2 2 1 0 2 2 2 1 Dienelactone hydrolase family Thioesterase PF00975.15 EGO61512.1 - 0.012 15.7 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain PhoPQ_related PF10142.4 EGO61512.1 - 0.024 13.1 0.0 0.035 12.5 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein PGAP1 PF07819.8 EGO61512.1 - 0.028 14.0 0.0 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein LIP PF03583.9 EGO61512.1 - 0.072 12.2 0.0 3.6 6.7 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Peptidase_S9 PF00326.16 EGO61512.1 - 0.11 11.6 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.8 EGO61512.1 - 0.13 11.6 0.0 1.3 8.3 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF915 PF06028.6 EGO61512.1 - 0.14 11.2 0.0 0.27 10.2 0.0 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PAP2 PF01569.16 EGO61514.1 - 8.1e-21 74.0 2.7 8.1e-21 74.0 1.9 1.8 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EGO61514.1 - 0.49 10.6 7.0 0.057 13.6 1.0 2.3 2 1 0 2 2 2 0 PAP2 superfamily C-terminal Bax1-I PF01027.15 EGO61514.1 - 1.3 8.6 12.3 1.5 8.4 1.0 2.3 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 SOG2 PF10428.4 EGO61515.1 - 0.44 9.1 8.2 0.59 8.7 5.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein 4HBT_3 PF13622.1 EGO61516.1 - 5.5e-37 127.8 0.0 6.3e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF829 PF05705.9 EGO61517.1 - 1.4e-68 231.1 0.1 1.6e-68 230.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) SRP54 PF00448.17 EGO61518.1 - 5.4e-76 254.4 3.5 1.2e-75 253.2 1.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EGO61518.1 - 5.1e-26 90.9 6.6 5.1e-26 90.9 4.6 3.7 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.14 EGO61518.1 - 1.2e-15 57.3 0.2 2.9e-15 56.1 0.1 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EGO61518.1 - 1.4e-08 34.4 0.3 4.1e-08 32.8 0.1 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EGO61518.1 - 4e-06 26.7 0.1 1.1e-05 25.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain MobB PF03205.9 EGO61518.1 - 7.3e-06 25.7 0.0 1.9e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EGO61518.1 - 9.5e-06 26.4 0.0 2.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EGO61518.1 - 0.0001 21.8 0.2 0.00037 19.9 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EGO61518.1 - 0.00027 19.7 3.3 0.00032 19.5 0.0 2.4 3 0 0 3 3 3 1 ArgK protein AAA_31 PF13614.1 EGO61518.1 - 0.00054 19.9 0.0 0.21 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EGO61518.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_10 PF12846.2 EGO61518.1 - 0.0019 17.7 0.2 0.0033 16.9 0.1 1.4 1 0 0 1 1 1 1 AAA-like domain ATP_bind_1 PF03029.12 EGO61518.1 - 0.0035 16.9 0.2 0.017 14.6 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EGO61518.1 - 0.0037 17.5 0.0 0.01 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGO61518.1 - 0.0041 17.1 0.1 0.013 15.5 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain Thymidylate_kin PF02223.12 EGO61518.1 - 0.0043 16.4 0.1 0.03 13.7 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase AAA PF00004.24 EGO61518.1 - 0.0044 17.2 0.1 0.019 15.1 0.0 2.3 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EGO61518.1 - 0.007 15.6 1.6 3.3 6.8 0.8 3.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EGO61518.1 - 0.0077 16.3 0.1 0.029 14.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EGO61518.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin VirC1 PF07015.6 EGO61518.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein LpxK PF02606.9 EGO61518.1 - 0.026 13.5 0.1 0.1 11.5 0.0 1.9 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase TrwB_AAD_bind PF10412.4 EGO61518.1 - 0.033 12.8 0.0 0.082 11.5 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.1 EGO61518.1 - 0.034 14.1 0.2 0.069 13.0 0.2 1.7 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 EGO61518.1 - 0.043 13.0 0.1 0.22 10.7 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family 6PF2K PF01591.13 EGO61518.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase VirE PF05272.6 EGO61518.1 - 0.088 12.2 0.0 0.26 10.7 0.0 1.7 1 0 0 1 1 1 0 Virulence-associated protein E AAA_25 PF13481.1 EGO61518.1 - 0.1 11.9 0.0 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Abhydrolase_5 PF12695.2 EGO61518.1 - 0.15 11.7 1.7 2.2 8.0 0.0 2.8 2 1 0 2 2 2 0 Alpha/beta hydrolase family MFS_1 PF07690.11 EGO61520.1 - 7.5e-34 116.9 27.8 8.2e-34 116.8 18.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MMPL PF03176.10 EGO61520.1 - 0.1 11.3 0.3 1.7 7.2 0.0 2.2 2 0 0 2 2 2 0 MMPL family Peptidase_M20 PF01546.23 EGO61522.1 - 1.3e-08 34.5 0.0 1.8e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGO61522.1 - 1.7e-05 24.5 0.0 5.7e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.11 EGO61523.1 - 4.4e-22 78.2 14.0 4.4e-22 78.2 9.7 4.3 3 1 1 4 4 4 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO61523.1 - 1.2e-09 37.3 1.0 1.2e-09 37.3 0.7 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter RasGAP PF00616.14 EGO61524.1 - 0.002 17.8 0.0 0.0054 16.4 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Hap4_Hap_bind PF10297.4 EGO61527.1 - 5.2e-09 35.6 6.0 1.1e-08 34.5 4.2 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EGO61527.1 - 2.6e-06 27.3 12.8 6.7e-06 25.9 5.5 2.7 2 1 1 3 3 3 1 bZIP transcription factor Tropomyosin_1 PF12718.2 EGO61527.1 - 0.064 13.1 5.2 0.12 12.2 3.6 1.4 1 0 0 1 1 1 0 Tropomyosin like dsrm PF00035.20 EGO61527.1 - 0.097 13.2 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif bZIP_2 PF07716.10 EGO61527.1 - 0.18 11.6 11.8 3.3 7.5 8.2 2.6 1 1 1 2 2 2 0 Basic region leucine zipper Striatin PF08232.7 EGO61527.1 - 0.2 11.9 6.3 0.22 11.8 3.2 1.8 1 1 1 2 2 2 0 Striatin family HAUS6_N PF14661.1 EGO61527.1 - 0.67 9.2 6.9 0.97 8.7 4.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Fmp27_WPPW PF10359.4 EGO61527.1 - 2.1 6.6 8.2 3 6.1 5.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain bZIP_Maf PF03131.12 EGO61527.1 - 4.2 7.7 16.6 0.97 9.7 5.4 2.7 1 1 1 2 2 2 0 bZIP Maf transcription factor IncA PF04156.9 EGO61527.1 - 5 6.6 10.8 9.4 5.7 7.5 1.4 1 0 0 1 1 1 0 IncA protein Med3 PF11593.3 EGO61527.1 - 6.8 5.8 15.4 1.1 8.4 7.5 1.8 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal SPT2 PF08243.6 EGO61527.1 - 7.3 6.9 10.4 0.5 10.6 3.6 1.8 2 0 0 2 2 2 0 SPT2 chromatin protein COG2 PF06148.6 EGO61528.1 - 8.3e-18 64.5 0.0 9.1e-17 61.1 0.0 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EGO61528.1 - 0.056 13.2 0.1 0.21 11.4 0.0 2.1 1 1 0 1 1 1 0 Vps51/Vps67 COG5 PF10392.4 EGO61528.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Ribosomal_L1 PF00687.16 EGO61529.1 - 1.9e-24 86.2 0.0 2.5e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.16 EGO61530.1 - 2.1e-102 341.9 0.9 2.3e-101 338.5 0.1 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGO61530.1 - 8.1e-40 136.3 0.3 1.6e-39 135.3 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 EGO61530.1 - 0.003 16.7 0.2 0.0073 15.4 0.2 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Striatin PF08232.7 EGO61530.1 - 0.025 14.8 3.6 0.07 13.4 2.5 1.7 1 0 0 1 1 1 0 Striatin family Choline_transpo PF04515.7 EGO61531.1 - 2.8e-105 351.7 18.2 2.8e-105 351.7 12.6 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF4191 PF13829.1 EGO61531.1 - 1.9 7.5 9.3 0.073 12.1 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) WAPL PF07814.8 EGO61532.1 - 0.28 9.8 0.0 0.43 9.2 0.0 1.2 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin IPPT PF01715.12 EGO61533.1 - 4.6e-51 173.2 2.5 5.8e-51 172.9 0.1 2.2 2 1 0 2 2 2 1 IPP transferase zf-C2H2_jaz PF12171.3 EGO61533.1 - 1.3e-05 25.2 6.1 2.5e-05 24.2 4.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_17 PF13207.1 EGO61533.1 - 2.2e-05 25.2 0.3 0.00012 22.9 0.0 2.5 2 2 0 2 2 2 1 AAA domain IPT PF01745.11 EGO61533.1 - 3e-05 23.3 0.0 8.8e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 Isopentenyl transferase zf-met PF12874.2 EGO61533.1 - 7.5e-05 22.7 3.1 0.00017 21.6 2.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EGO61533.1 - 0.00018 21.5 0.6 0.00034 20.6 0.4 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) AAA_18 PF13238.1 EGO61533.1 - 0.00039 20.7 2.1 0.094 13.0 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EGO61533.1 - 0.0032 17.3 0.3 0.096 12.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EGO61533.1 - 0.0061 16.7 0.1 0.031 14.4 0.0 2.2 3 0 0 3 3 3 1 AAA domain zf-DBF PF07535.7 EGO61533.1 - 0.0075 15.9 0.9 0.016 14.8 0.7 1.4 1 0 0 1 1 1 1 DBF zinc finger RNA_helicase PF00910.17 EGO61533.1 - 0.015 15.4 0.0 0.046 13.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EGO61533.1 - 0.024 14.5 0.2 0.56 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.7 EGO61533.1 - 0.059 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_25 PF13481.1 EGO61533.1 - 0.072 12.4 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EGO61533.1 - 0.088 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) tRNA-synt_1g PF09334.6 EGO61533.1 - 1 7.9 4.7 3.8 6.0 3.3 1.9 1 1 0 1 1 1 0 tRNA synthetases class I (M) zf-C2H2_4 PF13894.1 EGO61533.1 - 1.7 9.1 5.7 0.23 11.8 0.9 1.9 2 0 0 2 2 1 0 C2H2-type zinc finger SecY PF00344.15 EGO61534.1 - 2.1e-96 322.9 10.8 2.6e-96 322.5 7.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EGO61534.1 - 2.2e-18 65.4 0.3 7.2e-18 63.8 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p RseC_MucC PF04246.7 EGO61534.1 - 1.3 8.5 3.8 0.58 9.7 0.0 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Aconitase PF00330.15 EGO61535.1 - 4.4e-69 233.1 0.1 2.3e-65 220.8 0.1 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGO61535.1 - 3.4e-23 82.2 0.0 6.3e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain KfrA_N PF11740.3 EGO61535.1 - 0.013 15.9 0.6 0.013 15.9 0.4 2.1 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Fungal_trans PF04082.13 EGO61536.1 - 3.9e-17 61.9 0.0 4.1e-16 58.6 0.0 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Matrilin_ccoil PF10393.4 EGO61536.1 - 0.08 12.3 0.5 0.18 11.1 0.3 1.6 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Oxidored_FMN PF00724.15 EGO61537.1 - 1.5e-53 181.9 0.0 2.1e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EGO61537.1 - 0.016 14.0 0.0 0.029 13.1 0.0 1.7 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) Zn_clus PF00172.13 EGO61538.1 - 2.8e-07 30.3 13.6 6.8e-07 29.0 9.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RAB3GAP2_N PF14655.1 EGO61538.1 - 0.054 12.5 3.8 0.11 11.4 2.7 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Peptidase_S15 PF02129.13 EGO61538.1 - 0.55 9.5 3.5 0.89 8.9 2.4 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Suf PF05843.9 EGO61538.1 - 0.73 9.5 6.6 0.055 13.1 1.2 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) AAA_23 PF13476.1 EGO61538.1 - 1.7 8.9 6.8 2.6 8.2 4.7 1.2 1 0 0 1 1 1 0 AAA domain SHR3_chaperone PF08229.6 EGO61538.1 - 5.6 5.8 7.8 11 4.8 5.4 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 Fig1 PF12351.3 EGO61539.1 - 1.1e-33 116.6 0.6 1.1e-33 116.6 0.4 1.3 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EGO61539.1 - 1.3e-06 28.1 1.2 2.8e-06 27.0 0.9 1.6 1 1 0 1 1 1 1 SUR7/PalI family TRAP_beta PF05753.9 EGO61539.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) Tetraspannin PF00335.15 EGO61539.1 - 1 8.5 5.8 0.26 10.5 0.3 2.1 2 0 0 2 2 2 0 Tetraspanin family Peroxidase_2 PF01328.12 EGO61540.1 - 1e-39 136.0 0.0 1.3e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Rad50_zn_hook PF04423.9 EGO61541.1 - 0.018 14.4 0.5 0.055 12.9 0.3 1.8 1 0 0 1 1 1 0 Rad50 zinc hook motif Methyltransf_33 PF10017.4 EGO61541.1 - 0.084 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Prp19_bind PF06991.6 EGO61541.1 - 0.49 9.6 11.7 0.63 9.2 8.1 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Nop10p PF04135.7 EGO61542.1 - 4.9e-17 61.3 0.1 8.6e-17 60.6 0.1 1.4 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family PRiA4_ORF3 PF07929.6 EGO61542.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.4 1 1 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein DUF3520 PF12034.3 EGO61542.1 - 0.02 14.9 0.3 0.023 14.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3520) NOB1_Zn_bind PF08772.6 EGO61543.1 - 1.6e-31 107.9 4.2 3.4e-31 106.9 2.9 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 EGO61543.1 - 0.00044 20.0 16.1 0.0023 17.7 11.1 2.2 1 1 0 1 1 1 1 Drug resistance and apoptosis regulator CENP-T PF15511.1 EGO61543.1 - 0.01 15.0 8.3 0.02 14.1 5.8 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T zf-NADH-PPase PF09297.6 EGO61543.1 - 0.27 10.7 6.4 0.056 12.9 0.9 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain FDF PF09532.5 EGO61543.1 - 0.44 11.1 11.2 1.1 9.8 7.8 1.6 1 0 0 1 1 1 0 FDF domain RR_TM4-6 PF06459.7 EGO61543.1 - 1.8 8.4 9.7 2.9 7.7 6.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF605 PF04652.11 EGO61544.1 - 0.15 11.4 7.3 0.2 11.0 5.1 1.1 1 0 0 1 1 1 0 Vta1 like Dexa_ind PF15198.1 EGO61544.1 - 4.8 7.1 5.9 9.3 6.2 4.1 1.4 1 0 0 1 1 1 0 Dexamethasone-induced CbiA PF01656.18 EGO61545.1 - 0.043 13.2 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF724 PF05266.9 EGO61545.1 - 0.058 13.0 0.5 0.068 12.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Bys1 PF04681.7 EGO61546.1 - 4.7e-13 49.1 0.6 5.8e-13 48.8 0.4 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Glyco_hydro_72 PF03198.9 EGO61547.1 - 3.8e-124 413.7 6.0 5.2e-124 413.3 4.1 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EGO61547.1 - 1.1e-23 83.5 4.9 1.1e-23 83.5 3.4 2.1 2 0 0 2 2 2 1 X8 domain Glyco_hydro_2_C PF02836.12 EGO61547.1 - 1.3e-05 24.2 0.1 2.2e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain CFC PF09443.5 EGO61547.1 - 0.11 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) SDA1 PF05285.7 EGO61551.1 - 0.00027 20.3 20.3 0.00038 19.8 14.1 1.1 1 0 0 1 1 1 1 SDA1 SprA-related PF12118.3 EGO61551.1 - 0.00042 19.7 14.5 0.00051 19.4 10.1 1.2 1 0 0 1 1 1 1 SprA-related family Nop14 PF04147.7 EGO61551.1 - 0.0098 13.8 23.2 0.011 13.6 16.1 1.1 1 0 0 1 1 1 1 Nop14-like family Toxin_17 PF08086.6 EGO61551.1 - 0.01 15.8 0.6 0.023 14.7 0.4 1.6 1 0 0 1 1 1 0 Ergtoxin family Hid1 PF12722.2 EGO61551.1 - 0.28 8.8 18.2 0.32 8.6 12.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.10 EGO61551.1 - 0.61 8.6 10.1 0.9 8.0 7.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF966 PF06136.8 EGO61551.1 - 1.6 8.0 27.2 0.24 10.7 16.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF966) PLRV_ORF5 PF01690.12 EGO61551.1 - 2.3 7.2 19.8 0.42 9.6 7.7 2.1 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein DUF2146 PF10220.4 EGO61551.1 - 3.6 5.4 19.5 4.5 5.1 13.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Hex_IIIa PF02455.11 EGO61551.1 - 4.1 5.9 13.6 6.1 5.4 9.4 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Herpes_UL32 PF06070.6 EGO61551.1 - 4.6 5.5 26.5 1.5 7.1 16.1 1.4 1 1 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF936 PF06075.7 EGO61551.1 - 5 5.9 29.5 6.6 5.5 20.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Nucleo_P87 PF07267.6 EGO61551.1 - 6.6 5.2 7.9 7.4 5.1 5.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Glyco_transf_20 PF00982.16 EGO61554.1 - 0.00029 19.4 0.8 0.002 16.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 20 DAP PF15228.1 EGO61554.1 - 0.00091 19.9 0.6 0.002 18.8 0.4 1.6 1 0 0 1 1 1 1 Death-associated protein Ndr PF03096.9 EGO61554.1 - 0.096 11.1 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF3899 PF13038.1 EGO61555.1 - 0.0073 16.4 0.5 0.0084 16.2 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3899) BLVR PF06375.6 EGO61555.1 - 0.071 12.9 0.9 0.082 12.7 0.6 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Vfa1 PF08432.5 EGO61556.1 - 0.012 15.6 9.5 0.015 15.3 6.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3450 PF11932.3 EGO61556.1 - 0.038 13.2 2.6 0.054 12.7 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) COX16 PF14138.1 EGO61556.1 - 0.19 11.9 3.6 0.27 11.4 2.5 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Hamartin PF04388.7 EGO61556.1 - 0.22 10.1 2.3 0.29 9.7 1.6 1.0 1 0 0 1 1 1 0 Hamartin protein DUF2681 PF10883.3 EGO61556.1 - 0.24 11.6 2.0 0.55 10.4 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CT47 PF15623.1 EGO61556.1 - 0.25 11.0 10.9 0.34 10.6 7.6 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Med3 PF11593.3 EGO61556.1 - 2.5 7.2 10.2 3.2 6.8 7.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NARP1 PF12569.3 EGO61556.1 - 3.7 6.1 9.5 4.9 5.7 6.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3222 PF11519.3 EGO61557.1 - 0.045 13.7 0.1 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3222) RELT PF12606.3 EGO61559.1 - 0.36 9.9 1.5 0.69 9.0 1.1 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 SNF2_N PF00176.18 EGO61560.1 - 7.3e-72 241.6 2.2 1.2e-71 240.9 1.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EGO61560.1 - 4.5e-51 172.5 16.8 4.5e-51 172.5 11.7 5.1 4 2 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.26 EGO61560.1 - 4.8e-16 58.3 0.0 1.3e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Phage_30_3 PF08010.6 EGO61560.1 - 0.46 9.9 5.2 0.2 11.1 0.1 2.8 3 0 0 3 3 3 0 Bacteriophage protein GP30.3 ABC_tran PF00005.22 EGO61561.1 - 2.1e-47 160.8 0.0 1.2e-22 80.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGO61561.1 - 6.3e-21 75.5 1.0 0.00013 22.0 0.0 4.2 3 1 1 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 EGO61561.1 - 1.8e-20 72.5 3.4 1.8e-20 72.5 2.4 2.9 4 0 0 4 4 2 1 ABC transporter SMC_N PF02463.14 EGO61561.1 - 4.8e-12 45.5 0.1 0.0001 21.6 0.0 4.5 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGO61561.1 - 6.2e-10 39.7 0.9 0.023 14.9 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EGO61561.1 - 1.6e-09 37.1 0.0 0.00098 18.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EGO61561.1 - 1.8e-06 28.1 0.0 0.054 13.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGO61561.1 - 2e-06 27.9 1.1 0.045 13.7 0.0 3.2 3 1 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 EGO61561.1 - 2.5e-06 26.7 0.0 0.0061 15.7 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGO61561.1 - 3.7e-06 27.7 0.1 0.07 13.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 EGO61561.1 - 8.6e-06 25.5 0.2 0.16 11.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 EGO61561.1 - 1.5e-05 25.2 0.1 0.053 13.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EGO61561.1 - 1.6e-05 24.8 0.0 0.13 12.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EGO61561.1 - 1.7e-05 25.2 0.0 0.049 14.1 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 EGO61561.1 - 2.4e-05 24.2 0.2 0.28 11.0 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.1 EGO61561.1 - 2.8e-05 24.1 0.0 0.018 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGO61561.1 - 3.9e-05 23.8 0.1 0.54 10.4 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGO61561.1 - 8.3e-05 22.0 0.0 0.46 9.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 EGO61561.1 - 8.7e-05 22.2 0.1 0.45 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EGO61561.1 - 0.00022 21.3 0.6 1.4 9.1 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA_10 PF12846.2 EGO61561.1 - 0.0003 20.3 0.6 0.84 9.0 0.1 3.3 4 0 0 4 4 3 2 AAA-like domain Arch_ATPase PF01637.13 EGO61561.1 - 0.00045 19.9 0.1 0.39 10.3 0.0 2.9 3 0 0 3 3 3 1 Archaeal ATPase AAA_14 PF13173.1 EGO61561.1 - 0.00064 19.6 0.0 1.7 8.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EGO61561.1 - 0.00067 18.8 0.1 0.15 11.0 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain DUF2813 PF11398.3 EGO61561.1 - 0.0016 17.5 0.3 0.81 8.7 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) NB-ARC PF00931.17 EGO61561.1 - 0.0025 16.6 0.3 1.1 8.0 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain SbcCD_C PF13558.1 EGO61561.1 - 0.0037 17.1 0.3 0.44 10.4 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EGO61561.1 - 0.0061 16.2 0.1 0.36 10.5 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_ATPase PF09818.4 EGO61561.1 - 0.016 13.7 0.2 12 4.3 0.0 3.4 3 1 0 3 3 3 0 Predicted ATPase of the ABC class Dynamin_N PF00350.18 EGO61561.1 - 0.017 14.9 0.7 11 5.7 0.0 3.8 4 1 0 5 5 5 0 Dynamin family DAP3 PF10236.4 EGO61561.1 - 0.02 13.8 1.0 2.4 7.0 0.1 2.8 2 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.10 EGO61561.1 - 0.049 13.3 0.1 6.9 6.3 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_13 PF13166.1 EGO61561.1 - 0.056 11.9 0.5 12 4.1 0.0 3.5 3 1 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 EGO61561.1 - 0.066 12.6 0.0 0.87 9.0 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.13 EGO61561.1 - 0.067 12.4 0.3 14 4.8 0.0 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B DUF815 PF05673.8 EGO61561.1 - 0.068 12.0 0.5 2.1 7.1 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 EGO61561.1 - 0.078 12.4 0.7 6.7 6.2 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 EGO61561.1 - 0.26 11.0 3.4 10 5.8 0.0 3.2 4 0 0 4 4 3 0 Domain of unknown function DUF87 AAA_24 PF13479.1 EGO61561.1 - 0.72 9.3 4.4 9.8 5.6 0.0 3.7 4 0 0 4 4 4 0 AAA domain Ins145_P3_rec PF08709.6 EGO61562.1 - 0.025 13.6 0.1 0.053 12.5 0.1 1.4 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor DUF1469 PF07332.6 EGO61563.1 - 4.2 7.1 8.6 0.79 9.4 3.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) YrhC PF14143.1 EGO61563.1 - 9.8 6.2 7.5 12 5.9 2.7 2.9 2 1 1 3 3 3 0 YrhC-like protein S1FA PF04689.8 EGO61565.1 - 0.092 12.6 0.4 0.92 9.4 0.0 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA MscS_TM PF12794.2 EGO61565.1 - 0.13 10.8 0.1 0.19 10.2 0.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2305 PF10230.4 EGO61566.1 - 6e-57 193.0 0.3 1.7e-43 148.9 0.0 2.1 1 1 0 2 2 2 2 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EGO61566.1 - 0.00021 21.2 0.1 0.00034 20.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGO61566.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGO61566.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Mito_carr PF00153.22 EGO61567.1 - 0.0012 18.4 0.0 0.0053 16.4 0.0 2.2 2 1 0 2 2 2 1 Mitochondrial carrier protein Zip PF02535.17 EGO61567.1 - 0.008 15.2 12.3 0.013 14.4 8.5 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter Neur_chan_memb PF02932.11 EGO61567.1 - 0.058 13.2 2.4 0.088 12.6 1.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2946 PF11162.3 EGO61567.1 - 0.17 12.0 10.9 0.096 12.8 5.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) DUF3984 PF13136.1 EGO61567.1 - 2 7.5 25.9 0.12 11.5 13.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) Macoilin PF09726.4 EGO61567.1 - 2.7 6.1 8.2 3.7 5.6 5.7 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 EGO61567.1 - 2.7 7.2 14.2 4.6 6.5 9.8 1.3 1 0 0 1 1 1 0 Vta1 like SelP_N PF04592.9 EGO61567.1 - 5.1 6.3 22.9 9.6 5.5 15.9 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SdpI PF13630.1 EGO61571.1 - 0.013 15.2 7.7 0.024 14.3 5.3 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF2207 PF09972.4 EGO61571.1 - 0.068 11.7 2.5 0.092 11.3 1.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.1 EGO61571.1 - 0.22 11.9 3.1 0.53 10.7 2.2 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 EGO61571.1 - 0.55 9.9 1.4 0.89 9.2 1.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Prominin PF05478.6 EGO61571.1 - 1.4 6.3 3.5 2 5.8 2.4 1.1 1 0 0 1 1 1 0 Prominin SP_C-Propep PF08999.5 EGO61571.1 - 2.1 7.9 5.3 4.4 6.8 3.7 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Ly49 PF08391.5 EGO61571.1 - 3.9 7.6 5.5 7.6 6.6 3.8 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF929 PF06053.6 EGO61571.1 - 9.4 5.2 8.3 20 4.1 5.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Glyco_transf_25 PF01755.12 EGO61573.1 - 1.6e-11 44.2 0.0 3.3e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) MFS_1 PF07690.11 EGO61574.1 - 5.3e-14 51.7 21.5 5.3e-14 51.7 14.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ABC2_membrane PF01061.19 EGO61575.1 - 7.4e-89 296.4 42.7 1.1e-47 161.9 10.8 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EGO61575.1 - 5.4e-43 146.5 0.0 3.6e-19 69.4 0.0 3.4 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EGO61575.1 - 7.8e-31 105.7 3.8 1.7e-27 95.0 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EGO61575.1 - 7.4e-11 41.6 34.6 3.5e-08 32.8 11.6 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EGO61575.1 - 2e-06 27.8 0.0 5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EGO61575.1 - 2.1e-06 27.2 0.3 0.004 16.5 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGO61575.1 - 8e-05 22.7 0.1 0.23 11.6 0.0 3.2 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EGO61575.1 - 0.00019 21.3 0.1 0.54 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGO61575.1 - 0.00021 20.5 0.1 0.01 15.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGO61575.1 - 0.00024 21.1 0.4 0.14 12.1 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EGO61575.1 - 0.00033 20.9 0.0 1.3 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 EGO61575.1 - 0.00062 19.2 1.6 0.43 9.9 0.4 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EGO61575.1 - 0.00074 20.3 0.0 1.5 9.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGO61575.1 - 0.0011 18.4 0.4 0.076 12.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EGO61575.1 - 0.0014 18.6 0.7 0.51 10.2 0.4 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGO61575.1 - 0.013 15.7 0.1 2.4 8.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGO61575.1 - 0.013 15.2 1.3 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_21 PF13304.1 EGO61575.1 - 0.036 14.0 0.0 0.87 9.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EGO61575.1 - 0.039 13.6 0.8 2.8 7.5 0.2 2.3 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 EGO61575.1 - 0.066 12.2 0.1 12 4.9 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.4 EGO61575.1 - 0.079 12.4 0.7 1.6 8.2 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 EGO61575.1 - 0.084 11.7 0.2 0.79 8.5 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EGO61575.1 - 0.085 12.8 0.1 9.9 6.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EGO61575.1 - 0.16 11.6 0.0 18 4.8 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 EGO61575.1 - 0.99 8.9 2.6 13 5.2 0.2 2.9 3 0 0 3 3 3 0 AAA domain Fungal_trans PF04082.13 EGO61576.1 - 9.6e-14 50.8 0.2 9.6e-14 50.8 0.1 2.3 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO61576.1 - 1e-06 28.5 9.0 1.8e-06 27.7 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Jiraiya PF15038.1 EGO61576.1 - 0.014 14.8 1.5 0.026 13.9 1.0 1.3 1 0 0 1 1 1 0 Jiraiya DUF853 PF05872.7 EGO61578.1 - 0.078 11.3 0.0 0.12 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Mu-like_Com PF10122.4 EGO61578.1 - 7.1 5.7 7.9 2.6 7.1 0.9 2.8 3 0 0 3 3 3 0 Mu-like prophage protein Com zf-C3HC4_3 PF13920.1 EGO61579.1 - 6.9 6.4 7.4 29 4.4 5.1 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SET PF00856.23 EGO61580.1 - 9.1e-12 45.5 0.0 1.4e-10 41.7 0.0 2.4 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 EGO61580.1 - 4.4e-06 26.6 0.1 9.2e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Ribonucleas_3_3 PF14622.1 EGO61581.1 - 9.6e-33 112.8 0.0 1.7e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Bunya_NS-S PF01104.12 EGO61581.1 - 0.15 11.5 0.2 0.34 10.3 0.1 1.6 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s KAT11 PF08214.6 EGO61582.1 - 2.7e-98 329.2 0.0 4.2e-98 328.6 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein TRI12 PF06609.8 EGO61586.1 - 3.6e-23 81.6 15.0 5.5e-23 81.0 10.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EGO61586.1 - 1e-21 77.0 45.5 5.4e-21 74.6 31.6 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 EGO61587.1 - 1.4e-19 70.3 0.1 6e-12 45.2 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGO61587.1 - 9.4e-09 34.6 0.6 2.1e-05 23.6 0.2 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGO61587.1 - 1.5e-06 27.3 1.0 2.4e-06 26.6 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGO61587.1 - 3.8e-06 26.8 0.4 8.5e-06 25.7 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGO61587.1 - 2e-05 24.5 0.2 7.6e-05 22.6 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGO61587.1 - 0.00033 19.8 0.0 0.00053 19.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EGO61587.1 - 0.0011 17.9 0.2 0.0015 17.4 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EGO61587.1 - 0.0012 17.4 0.4 0.0019 16.7 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EGO61587.1 - 0.0022 18.3 0.9 0.018 15.4 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGO61587.1 - 0.0033 16.5 0.9 0.0045 16.1 0.3 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGO61587.1 - 0.0077 16.3 0.2 0.016 15.2 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EGO61587.1 - 0.043 13.3 0.9 0.14 11.6 0.1 2.1 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EGO61587.1 - 0.049 13.0 0.1 0.087 12.2 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EGO61587.1 - 0.07 12.8 0.1 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 EGO61587.1 - 0.089 11.4 0.0 0.3 9.6 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 EGO61587.1 - 0.12 11.2 0.2 0.27 10.0 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein SE PF08491.5 EGO61587.1 - 0.15 10.8 0.0 0.33 9.7 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase DUF1351 PF07083.6 EGO61588.1 - 0.004 16.8 1.0 0.0061 16.2 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1351) NMT1 PF09084.6 EGO61588.1 - 0.0099 15.4 0.0 2.4 7.7 0.0 3.0 1 1 1 2 2 2 2 NMT1/THI5 like DUF1795 PF08786.6 EGO61588.1 - 0.068 13.0 0.1 0.88 9.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1795) Ytp1 PF10355.4 EGO61589.1 - 4.8e-86 288.3 16.5 4.8e-86 288.3 11.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EGO61589.1 - 2e-33 114.0 4.3 2e-33 114.0 3.0 3.0 4 1 0 4 4 4 1 Domain of unknown function (DUF2427) MFS_1 PF07690.11 EGO61590.1 - 2.5e-36 125.1 40.7 2.5e-36 125.1 28.2 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGO61590.1 - 8.8e-17 60.8 29.6 1.5e-16 60.0 20.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Acyltransferase PF01553.16 EGO61591.1 - 2.4e-23 82.0 0.0 3.6e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase NAD_kinase PF01513.16 EGO61592.1 - 3.5e-50 170.4 0.0 1.3e-49 168.5 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase TauD PF02668.11 EGO61594.1 - 1.9e-29 103.1 0.0 2.4e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pox_F11 PF04943.7 EGO61595.1 - 0.028 13.2 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus F11 protein Zn_clus PF00172.13 EGO61595.1 - 0.07 13.0 5.4 0.18 11.7 3.7 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_11 PF13414.1 EGO61596.1 - 4.7e-14 51.7 0.2 1.7e-08 33.9 0.1 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGO61596.1 - 1.3e-11 43.4 3.3 7.2e-06 25.5 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGO61596.1 - 3.8e-11 42.0 0.4 8.4e-05 22.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGO61596.1 - 6.7e-06 25.9 0.7 0.00042 20.2 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGO61596.1 - 0.00045 20.7 4.0 0.0047 17.5 0.7 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGO61596.1 - 0.0017 18.7 1.8 0.022 15.3 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGO61596.1 - 0.0023 17.5 0.3 0.23 11.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGO61596.1 - 0.0094 16.2 0.5 0.033 14.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGO61596.1 - 0.013 15.3 1.7 0.18 11.7 0.1 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat SPO22 PF08631.5 EGO61596.1 - 0.015 14.3 0.3 0.57 9.2 0.0 2.2 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_17 PF13431.1 EGO61596.1 - 0.061 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGO61596.1 - 0.13 12.7 1.1 0.48 11.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGO61596.1 - 0.21 12.1 2.8 1.3 9.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat N-glycanase_C PF09113.5 EGO61598.1 - 0.76 9.4 8.9 1.5 8.4 6.2 1.5 1 0 0 1 1 1 0 Peptide-N-glycosidase F, C terminal Endomucin PF07010.7 EGO61599.1 - 0.011 15.1 5.0 0.013 14.8 3.5 1.0 1 0 0 1 1 1 0 Endomucin Elicitin PF00964.12 EGO61599.1 - 3.8 7.5 13.4 0.54 10.2 2.4 2.5 1 1 1 2 2 2 0 Elicitin Serglycin PF04360.7 EGO61600.1 - 3.7 7.2 10.3 6.9 6.3 7.1 1.5 1 0 0 1 1 1 0 Serglycin AA_permease_2 PF13520.1 EGO61602.1 - 9.5e-83 278.0 26.9 1.2e-82 277.7 18.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGO61602.1 - 7.2e-26 90.5 23.7 9.4e-26 90.1 16.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2619 PF10942.3 EGO61602.1 - 0.045 13.6 0.4 0.045 13.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2619) Aa_trans PF01490.13 EGO61602.1 - 0.067 11.6 16.6 0.025 13.0 8.2 2.5 2 1 0 2 2 2 0 Transmembrane amino acid transporter protein tRNA-synt_1b PF00579.20 EGO61603.1 - 2.7e-54 184.2 0.0 3.9e-54 183.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Sdh_cyt PF01127.17 EGO61604.1 - 2.6e-17 62.7 3.6 3.4e-17 62.3 2.5 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1546 PF07571.8 EGO61605.1 - 1.7e-30 104.9 0.0 3.2e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EGO61605.1 - 1.6e-21 76.0 0.0 4.2e-21 74.6 0.0 1.7 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EGO61605.1 - 0.0086 16.1 0.1 0.027 14.5 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 HEAT_2 PF13646.1 EGO61605.1 - 0.054 13.7 2.0 0.12 12.7 0.0 2.4 3 0 0 3 3 3 0 HEAT repeats Mucin PF01456.12 EGO61606.1 - 0.085 12.6 9.8 0.11 12.2 6.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein CAP_N PF01213.14 EGO61606.1 - 4 6.6 8.1 5.1 6.2 5.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Glyco_hydro_61 PF03443.9 EGO61608.1 - 6e-83 277.9 0.2 6e-83 277.9 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EGO61608.1 - 1.1e-13 50.5 14.2 2.6e-13 49.3 9.8 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain CSD PF00313.17 EGO61608.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain Gly_transf_sug PF04488.10 EGO61609.1 - 2.3e-17 63.2 0.0 3.6e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EGO61609.1 - 0.059 11.8 0.1 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Fringe PF02434.11 EGO61610.1 - 3.8e-07 29.5 0.3 5.8e-06 25.6 0.2 2.2 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.21 EGO61610.1 - 4.5e-05 23.1 0.0 8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 PAN domain Galactosyl_T PF01762.16 EGO61610.1 - 0.005 16.4 0.0 0.0094 15.5 0.0 1.4 1 0 0 1 1 1 1 Galactosyltransferase PAN_4 PF14295.1 EGO61610.1 - 0.023 14.3 0.5 0.042 13.5 0.4 1.4 1 0 0 1 1 1 0 PAN domain DUF1996 PF09362.5 EGO61611.1 - 3.9e-86 288.5 2.1 5.1e-86 288.1 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Beta-lactamase PF00144.19 EGO61615.1 - 1.5e-72 244.4 0.0 2.1e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase TPR_12 PF13424.1 EGO61616.1 - 1.7e-09 37.4 4.4 0.0001 22.1 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.17 EGO61616.1 - 3e-06 26.3 0.0 5.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 EGO61616.1 - 9e-06 25.2 0.2 0.01 15.4 0.2 3.5 3 0 0 3 3 3 1 TPR repeat AAA_16 PF13191.1 EGO61616.1 - 1.3e-05 25.2 0.0 4.2e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGO61616.1 - 3.5e-05 23.9 0.0 0.00016 21.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain TPR_2 PF07719.12 EGO61616.1 - 0.00018 21.1 2.9 11 6.2 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGO61616.1 - 0.00045 19.7 0.4 1.5 8.5 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EGO61616.1 - 0.0037 17.3 0.3 0.062 13.4 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EGO61616.1 - 0.011 16.0 0.1 0.12 12.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_25 PF13481.1 EGO61616.1 - 0.031 13.6 0.0 0.072 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_16 PF13432.1 EGO61616.1 - 0.064 13.9 0.0 2.3 9.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat KaiC PF06745.8 EGO61616.1 - 0.095 11.8 0.0 0.23 10.5 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.9 EGO61616.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Paf67 PF10255.4 EGO61616.1 - 0.17 10.7 0.2 0.36 9.6 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 adh_short PF00106.20 EGO61617.1 - 3e-16 59.7 4.2 7.6e-15 55.2 0.4 3.4 2 1 0 2 2 2 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 EGO61617.1 - 0.025 14.3 0.3 0.089 12.5 0.2 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EGO61617.1 - 0.038 13.0 0.0 0.092 11.8 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Thymidylate_kin PF02223.12 EGO61622.1 - 7.2e-41 139.6 0.1 2.2e-39 134.7 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.1 EGO61622.1 - 0.00046 20.1 0.0 0.0009 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain PRK PF00485.13 EGO61622.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.5 EGO61622.1 - 0.02 14.0 0.1 0.044 13.0 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 CPT PF07931.7 EGO61622.1 - 0.089 12.4 0.6 0.25 10.9 0.0 1.9 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein GTP_cyclohydroI PF01227.17 EGO61623.1 - 1.7e-74 248.9 0.3 1.9e-74 248.8 0.2 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EGO61623.1 - 0.0023 17.8 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein DegT_DnrJ_EryC1 PF01041.12 EGO61623.1 - 0.098 11.6 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family TAFII28 PF04719.9 EGO61624.1 - 6.8e-29 99.5 0.3 4.2e-27 93.7 0.0 2.2 2 0 0 2 2 2 2 hTAFII28-like protein conserved region CFEM PF05730.6 EGO61626.1 - 2.4e-12 46.5 12.7 2.9e-12 46.2 8.8 1.1 1 0 0 1 1 1 1 CFEM domain TIL PF01826.12 EGO61626.1 - 1.5 9.0 10.0 1.4 9.1 6.1 1.5 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain GAS PF13851.1 EGO61627.1 - 0.25 10.5 33.0 0.057 12.6 16.8 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2524 PF10732.4 EGO61627.1 - 0.29 11.2 6.2 0.72 10.0 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) HAUS-augmin3 PF14932.1 EGO61627.1 - 1.8 7.7 23.0 0.038 13.1 8.9 2.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 APG6 PF04111.7 EGO61627.1 - 8.1 5.3 28.9 2.3 7.1 7.7 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Exo_endo_phos PF03372.18 EGO61628.1 - 1.6e-21 77.3 0.1 2.7e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EGO61628.1 - 1.3e-13 50.2 5.5 1.4e-06 27.7 0.3 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGO61628.1 - 1.2e-06 28.1 9.0 3.7e-05 23.3 0.8 2.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EGO61628.1 - 0.00026 20.6 4.2 8.8 6.8 0.0 4.5 4 0 0 4 4 4 3 Leucine Rich Repeat HDV_ag PF01517.13 EGO61628.1 - 0.0037 16.9 1.1 0.0063 16.2 0.8 1.2 1 0 0 1 1 1 1 Hepatitis delta virus delta antigen LRR_7 PF13504.1 EGO61628.1 - 0.014 15.4 3.9 22 5.8 0.0 4.5 4 0 0 4 4 4 0 Leucine rich repeat ApbE PF02424.10 EGO61629.1 - 0.033 13.4 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 ApbE family 4HBT_2 PF13279.1 EGO61631.1 - 1.8e-24 86.4 0.2 3.4e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EGO61631.1 - 0.003 17.6 0.0 0.0067 16.5 0.0 1.7 1 0 0 1 1 1 1 Thioesterase superfamily Complex1_LYR PF05347.10 EGO61632.1 - 1.5e-07 31.1 0.1 2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGO61632.1 - 9.2e-07 28.9 0.1 1.1e-06 28.7 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EGO61632.1 - 2.4e-06 27.9 0.1 2.7e-06 27.7 0.1 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Methyltransf_25 PF13649.1 EGO61633.1 - 5.2e-09 36.3 0.0 1.3e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGO61633.1 - 1.3e-06 28.1 0.0 2.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGO61633.1 - 4.1e-06 26.4 0.0 0.079 12.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EGO61633.1 - 5.8e-06 26.3 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGO61633.1 - 7.9e-06 26.4 0.0 3.6e-05 24.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGO61633.1 - 8.1e-06 26.2 0.0 6.1e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGO61633.1 - 0.00023 21.5 0.0 0.0015 18.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGO61633.1 - 0.0065 15.6 0.0 1.8 7.5 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family CheR PF01739.13 EGO61633.1 - 0.0078 15.5 0.0 0.029 13.6 0.0 1.8 1 1 0 1 1 1 1 CheR methyltransferase, SAM binding domain Cerato-platanin PF07249.7 EGO61635.1 - 1.3e-61 205.8 3.1 1.5e-61 205.6 2.1 1.0 1 0 0 1 1 1 1 Cerato-platanin Fungal_trans PF04082.13 EGO61637.1 - 1.8e-13 49.9 3.9 1.8e-13 49.9 2.7 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO61637.1 - 1.7e-10 40.6 10.4 3e-10 39.8 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioesterase PF00975.15 EGO61640.1 - 3e-10 40.7 0.3 0.0046 17.2 0.0 3.3 3 1 0 3 3 3 3 Thioesterase domain Abhydrolase_6 PF12697.2 EGO61640.1 - 0.0029 17.5 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGO61640.1 - 0.0092 15.7 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Mito_carr PF00153.22 EGO61641.1 - 8e-18 63.9 0.3 9.6e-05 22.0 0.0 5.5 4 1 0 4 4 4 4 Mitochondrial carrier protein Herpes_pp85 PF04637.7 EGO61641.1 - 0.31 9.2 2.0 0.53 8.5 1.4 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Fer2 PF00111.22 EGO61642.1 - 6.2e-12 45.0 0.8 9.1e-12 44.5 0.5 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF3682 PF12446.3 EGO61643.1 - 0.6 10.4 3.0 1.3 9.3 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) ECSIT PF06239.6 EGO61644.1 - 0.18 10.6 1.6 4.1 6.1 0.0 2.9 2 1 1 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway CTX_RstB PF07459.6 EGO61647.1 - 0.058 13.2 0.0 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 CTX phage RstB protein YbgT_YccB PF08173.6 EGO61650.1 - 0.28 11.0 2.9 0.88 9.4 2.0 1.9 1 0 0 1 1 1 0 Membrane bound YbgT-like protein Aminotran_5 PF00266.14 EGO61651.1 - 7.7e-28 97.2 0.0 3.8e-12 45.6 0.0 3.6 3 1 0 3 3 3 3 Aminotransferase class-V F_bP_aldolase PF01116.15 EGO61654.1 - 3.6e-98 328.2 0.0 4.1e-98 328.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PHTB1_C PF14728.1 EGO61654.1 - 0.047 12.4 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 PTHB1 C-terminus ABM PF03992.11 EGO61655.1 - 1.8e-07 31.0 0.1 4.2e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase BCL_N PF04714.8 EGO61655.1 - 2.6 7.6 7.9 22 4.7 5.5 2.3 1 1 0 1 1 1 0 BCL7, N-terminal conserver region Imm6 PF14434.1 EGO61658.1 - 0.18 11.5 1.8 0.5 10.0 0.1 2.0 2 0 0 2 2 2 0 Immunity protein Imm6 GSDH PF07995.6 EGO61659.1 - 0.00034 19.8 0.1 0.00057 19.0 0.0 1.5 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase PGBA_C PF15437.1 EGO61660.1 - 0.084 13.0 1.4 0.19 11.8 1.0 1.5 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal bZIP_C PF12498.3 EGO61661.1 - 0.13 13.4 9.9 2.9 9.1 5.9 2.5 2 0 0 2 2 2 0 Basic leucine-zipper C terminal DUF89 PF01937.14 EGO61662.1 - 6.7e-131 436.2 0.1 7.7e-131 436.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Fungal_trans PF04082.13 EGO61665.1 - 5.5e-15 54.9 0.2 8.1e-15 54.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EGO61665.1 - 2.1e-12 46.7 22.3 9.8e-08 31.7 6.5 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain UvdE PF03851.9 EGO61667.1 - 7e-129 428.7 0.0 9.7e-129 428.2 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE WTF PF03303.8 EGO61668.1 - 0.86 8.9 3.6 0.42 9.9 0.4 1.9 2 0 0 2 2 2 0 WTF protein MliC PF09864.4 EGO61670.1 - 0.024 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Endostatin PF06482.6 EGO61670.1 - 0.28 10.5 7.1 0.093 12.1 1.4 2.2 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin CENP-C_C PF11699.3 EGO61671.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Mif2/CENP-C like Ribosomal_L27 PF01016.14 EGO61673.1 - 2.4e-23 81.7 0.9 5.2e-23 80.6 0.0 2.0 2 0 0 2 2 2 1 Ribosomal L27 protein DUF2076 PF09849.4 EGO61674.1 - 0.0034 17.4 0.2 0.0034 17.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF2946 PF11162.3 EGO61674.1 - 0.0079 16.3 4.0 0.0091 16.2 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) BAF1_ABF1 PF04684.8 EGO61674.1 - 7.6 5.2 9.7 9.3 4.9 6.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor IPP-2 PF04979.9 EGO61675.1 - 7.9e-12 45.5 8.1 6e-07 29.7 0.3 2.3 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) Sugar_tr PF00083.19 EGO61676.1 - 5.2e-81 272.5 19.6 6.4e-81 272.2 13.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGO61676.1 - 4.9e-13 48.5 30.3 1.6e-08 33.6 13.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 EGO61677.1 - 7.7e-07 28.0 0.4 0.00022 19.9 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF706 PF05153.10 EGO61678.1 - 3e-122 406.7 0.1 3.8e-122 406.4 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) CDC45 PF02724.9 EGO61680.1 - 0.41 8.6 5.9 0.55 8.2 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1003 PF06210.6 EGO61681.1 - 0.29 11.0 0.8 0.61 10.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Lipase_3 PF01764.20 EGO61685.1 - 4.4e-19 68.5 0.0 7.6e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) RAI16-like PF10257.4 EGO61686.1 - 6.2e-79 265.4 2.4 9.6e-79 264.8 1.7 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein SDA1 PF05285.7 EGO61686.1 - 0.36 10.0 9.9 0.58 9.3 6.9 1.2 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.7 EGO61686.1 - 2.2 8.0 7.9 4 7.2 5.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UPF0233 PF06781.7 EGO61687.1 - 0.05 13.2 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) TMEM247 PF15444.1 EGO61688.1 - 0.14 11.9 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 247 Apc13p PF05839.6 EGO61689.1 - 1.3e-37 127.5 0.2 2e-37 127.0 0.1 1.3 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.11 EGO61690.1 - 6.7e-38 129.6 0.0 7.8e-38 129.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component TIP120 PF08623.5 EGO61691.1 - 5.1e-67 224.6 0.8 4.6e-65 218.3 0.0 3.6 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EGO61691.1 - 4.4e-21 74.9 26.5 6.9e-06 26.2 0.1 9.5 7 3 4 11 11 11 6 HEAT repeats HEAT PF02985.17 EGO61691.1 - 6.7e-12 44.4 25.1 0.17 12.0 0.0 11.4 12 0 0 12 12 12 4 HEAT repeat HEAT_EZ PF13513.1 EGO61691.1 - 4e-08 33.4 26.5 1.5 9.4 0.0 12.3 13 1 0 13 13 13 2 HEAT-like repeat Cnd1 PF12717.2 EGO61691.1 - 6.3e-07 29.4 4.7 0.17 11.7 0.0 5.4 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EGO61691.1 - 3.5e-06 27.3 2.9 0.0077 16.5 0.0 6.2 6 2 1 7 7 7 1 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 EGO61691.1 - 9.6e-05 22.2 11.5 1.4 8.9 0.4 6.5 6 1 0 6 6 6 2 Protein of unknown function (DUF2435) Ipi1_N PF12333.3 EGO61691.1 - 0.027 14.4 0.0 15 5.6 0.0 4.0 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation DUF2457 PF10446.4 EGO61691.1 - 7.4 5.1 8.6 12 4.5 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Porphobil_deam PF01379.15 EGO61694.1 - 4.7e-75 251.2 0.0 6.7e-75 250.6 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EGO61694.1 - 2.8e-18 65.8 0.2 5.5e-18 64.8 0.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain PLAC8 PF04749.12 EGO61694.1 - 1.5e-15 57.6 0.5 2.6e-15 56.8 0.3 1.4 1 0 0 1 1 1 1 PLAC8 family Ras PF00071.17 EGO61695.1 - 7.8e-32 109.9 0.3 1e-31 109.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGO61695.1 - 3.5e-21 75.9 0.1 2.7e-20 73.0 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGO61695.1 - 3e-07 29.8 0.1 4.2e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGO61695.1 - 1.7e-05 24.0 0.2 2.3e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.6 EGO61695.1 - 0.0039 15.9 0.3 0.42 9.2 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 EGO61695.1 - 0.017 13.8 2.0 0.19 10.3 0.0 2.6 1 1 2 3 3 3 0 G-protein alpha subunit MMR_HSR1 PF01926.18 EGO61695.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase BRCT PF00533.21 EGO61697.1 - 0.00028 20.9 0.0 0.00073 19.6 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ycf1 PF05758.7 EGO61697.1 - 2.1 5.9 10.1 4 5.0 7.0 1.4 1 0 0 1 1 1 0 Ycf1 Aa_trans PF01490.13 EGO61698.1 - 1.1e-20 73.5 29.3 3.8e-19 68.4 16.8 2.5 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein Ndc80_HEC PF03801.8 EGO61700.1 - 0.064 12.6 0.5 0.14 11.5 0.2 1.6 1 1 1 2 2 2 0 HEC/Ndc80p family OMP_b-brl_3 PF14905.1 EGO61702.1 - 0.041 12.5 0.5 0.04 12.5 0.4 1.0 1 0 0 1 1 1 0 Outer membrane protein beta-barrel family GFO_IDH_MocA PF01408.17 EGO61704.1 - 7.1e-25 87.8 0.0 1.2e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGO61704.1 - 3.9e-14 52.4 0.0 9.1e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EGO61704.1 - 0.016 15.5 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain AAA_33 PF13671.1 EGO61704.1 - 0.08 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Semialdhyde_dh PF01118.19 EGO61704.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain