# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- MATalpha_HMGbox PF04769.12 CCD22170.1 - 1.1e-10 41.2 0.2 1.3e-10 40.9 0.2 1.1 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Defensin_2 PF01097.18 CCD22170.1 - 0.21 11.6 1.4 0.37 10.8 1.4 1.4 1 0 0 1 1 1 0 Arthropod defensin Homeobox_KN PF05920.11 CCD22171.1 - 1.4e-07 31.3 1.4 1.3e-06 28.2 0.3 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CCD22171.1 - 1.4e-06 28.0 1.3 3.3e-06 26.8 1.3 1.6 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CCD22171.1 - 0.011 15.2 0.1 0.025 14.0 0.1 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez PALP PF00291.25 CCD22172.1 - 4.3e-61 206.9 0.0 5.3e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Vac17 PF17321.2 CCD22173.1 - 4e-150 501.1 55.5 4.6e-150 500.9 55.5 1.0 1 0 0 1 1 1 1 Vacuole-related protein 17 MRC1 PF09444.10 CCD22174.1 - 2.8e-40 138.2 11.7 2.8e-40 138.2 11.7 6.9 5 1 3 8 8 8 1 MRC1-like domain KH_8 PF17903.1 CCD22175.1 - 3.7e-32 110.2 0.0 9.3e-32 109.0 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CCD22175.1 - 0.0054 16.5 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 KH domain DUF543 PF04418.12 CCD22177.1 - 9.4e-32 108.8 0.0 1.1e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Peptidase_M3 PF01432.20 CCD22178.1 - 6e-148 493.9 0.1 6e-148 493.9 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M3 Pneumo_M2 PF07380.11 CCD22178.1 - 2 8.8 7.4 0.17 12.2 0.4 2.9 3 1 0 3 3 3 0 Pneumovirus M2 protein PMC2NT PF08066.12 CCD22180.1 - 5.2 7.8 11.8 0.43 11.3 0.9 3.7 2 2 0 2 2 2 0 PMC2NT (NUC016) domain MT-A70 PF05063.14 CCD22181.1 - 9.7e-13 48.4 0.0 1.6e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Spb1_C PF07780.12 CCD22182.1 - 2.4e-81 272.4 24.6 2.4e-81 272.4 24.6 2.9 2 1 1 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 CCD22182.1 - 1.4e-53 181.6 0.1 3.5e-53 180.4 0.1 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CCD22182.1 - 4.1e-43 147.0 21.1 4.1e-43 147.0 21.1 5.8 6 0 0 6 6 6 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 CCD22182.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain SPATIAL PF15256.6 CCD22182.1 - 1.9 8.8 7.4 0.19 12.0 1.0 2.4 2 0 0 2 2 2 0 SPATIAL PIG-X PF08320.12 CCD22183.1 - 7.2e-28 97.9 0.0 1.2e-27 97.3 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 BSP_II PF05432.11 CCD22184.1 - 8.8 5.9 23.0 0.033 13.9 12.9 2.1 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) ATP_transf PF09830.9 CCD22185.1 - 8e-18 64.4 0.0 1.4e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 CCD22185.1 - 6.1e-06 25.7 0.3 8.7e-06 25.2 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4931) DUF4922 PF16269.5 CCD22185.1 - 0.00084 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4922) HIT PF01230.23 CCD22185.1 - 0.0018 19.0 0.1 0.0044 17.7 0.1 1.6 1 0 0 1 1 1 1 HIT domain Enamelin PF15362.6 CCD22186.1 - 5.5 5.2 9.7 5.7 5.1 9.7 1.0 1 0 0 1 1 1 0 Enamelin QCR10 PF09796.9 CCD22186.1 - 7 6.8 7.0 1.2 9.2 2.2 1.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Recep_L_domain PF01030.24 CCD22187.1 - 4.4e-09 36.4 17.5 4.9e-05 23.4 0.9 5.2 1 1 3 4 4 4 2 Receptor L domain CTP_transf_like PF01467.26 CCD22188.1 - 6.4e-08 32.9 0.0 1.2e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like EMC1_C PF07774.13 CCD22189.1 - 2.7e-63 213.5 0.0 5.9e-63 212.4 0.0 1.6 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal Mgr1 PF08602.10 CCD22190.1 - 4.3e-176 585.5 0.9 5.1e-176 585.2 0.9 1.1 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit Thioredoxin PF00085.20 CCD22191.1 - 4.9e-58 193.5 2.9 5.9e-30 103.3 0.2 3.8 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 CCD22191.1 - 5.2e-26 91.7 6.3 5.6e-20 72.0 1.7 4.0 3 1 1 4 4 4 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CCD22191.1 - 1.2e-09 37.9 0.2 6.4e-05 22.4 0.0 2.7 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CCD22191.1 - 2.5e-07 31.1 0.6 0.0072 16.8 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CCD22191.1 - 9.7e-07 28.9 0.0 0.04 14.1 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CCD22191.1 - 3e-06 27.5 0.3 0.36 11.2 0.0 4.2 3 2 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 CCD22191.1 - 2.8e-05 24.0 0.3 0.019 14.9 0.0 2.9 2 1 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.6 CCD22191.1 - 0.0073 16.1 0.8 2.4 7.9 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin Redoxin PF08534.10 CCD22191.1 - 0.0081 15.9 0.1 0.77 9.5 0.0 2.6 2 0 0 2 2 2 1 Redoxin DUF1539 PF07560.11 CCD22191.1 - 0.027 14.6 0.1 0.055 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Hexokinase_2 PF03727.16 CCD22192.1 - 1.4e-76 257.1 0.0 1.9e-76 256.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CCD22192.1 - 7e-73 244.8 0.0 1.1e-72 244.1 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Oxidored_FMN PF00724.20 CCD22193.1 - 1.3e-129 432.3 0.0 1.5e-129 432.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family WD40 PF00400.32 CCD22194.1 - 4e-16 59.1 3.3 0.0052 17.6 0.0 6.5 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD22194.1 - 1.7e-08 34.7 0.0 0.25 11.7 0.1 5.6 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain ATG22 PF11700.8 CCD22195.1 - 2e-149 498.3 21.3 2.5e-149 498.0 21.3 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Bac_export_2 PF01312.19 CCD22195.1 - 0.36 10.0 3.2 0.42 9.8 1.5 1.9 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family La PF05383.17 CCD22196.1 - 3.8e-19 68.5 0.3 8.8e-19 67.3 0.1 1.7 2 0 0 2 2 2 1 La domain TMEM214 PF10151.9 CCD22197.1 - 0.036 12.5 10.8 0.069 11.6 10.8 1.4 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator FAM176 PF14851.6 CCD22197.1 - 2.3 7.8 11.5 6.9 6.3 6.0 2.4 2 0 0 2 2 2 0 FAM176 family Zip PF02535.22 CCD22197.1 - 4.4 6.4 4.9 8 5.6 4.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4604 PF15377.6 CCD22197.1 - 6.1 7.2 30.5 6.1 7.2 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) GOLD_2 PF13897.6 CCD22197.1 - 8.5 6.9 10.6 4.2 7.9 3.6 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Glutaredoxin PF00462.24 CCD22198.1 - 1.3e-12 47.7 0.0 2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 CCD22198.1 - 0.0011 18.9 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.6 CCD22198.1 - 0.016 15.4 0.4 0.03 14.5 0.4 1.5 1 1 0 1 1 1 0 Thioredoxin GAT PF03127.14 CCD22199.1 - 0.0011 19.2 0.7 0.0039 17.5 0.1 2.2 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 CCD22199.1 - 0.0078 16.1 0.2 0.017 15.0 0.2 1.6 1 0 0 1 1 1 1 VHS domain SelR PF01641.18 CCD22200.1 - 3.7e-49 165.8 0.6 6.1e-49 165.1 0.6 1.3 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 CCD22200.1 - 0.024 14.6 0.3 2.7 8.1 0.1 2.2 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 CCD22200.1 - 0.056 13.2 0.7 2 8.2 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 CCD22200.1 - 0.093 12.9 2.5 0.15 12.2 1.0 2.0 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-Mss51 PF13824.6 CCD22200.1 - 0.36 11.0 5.9 1.3 9.1 0.4 3.3 3 1 1 4 4 4 0 Zinc-finger of mitochondrial splicing suppressor 51 DNA_RNApol_7kD PF03604.13 CCD22200.1 - 0.7 9.6 4.2 18 5.1 0.2 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit SAM_Ste50p PF09235.10 CCD22201.1 - 3.6e-22 78.4 4.0 7.5e-22 77.4 4.0 1.5 1 0 0 1 1 1 1 Ste50p, sterile alpha motif RA PF00788.23 CCD22201.1 - 3.7e-15 56.3 0.8 7.9e-15 55.3 0.8 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain CitMHS_2 PF16980.5 CCD22201.1 - 0.3 9.7 0.0 0.41 9.2 0.0 1.1 1 0 0 1 1 1 0 Putative citrate transport RRM_Rrp7 PF17799.1 CCD22202.1 - 1.4e-37 129.0 3.7 2.9e-37 128.0 3.7 1.5 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 CCD22202.1 - 5.5e-24 84.6 9.2 5.5e-24 84.6 9.2 1.8 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF547 PF04784.14 CCD22202.1 - 0.027 14.5 0.4 0.068 13.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF547 DUF45 PF01863.17 CCD22202.1 - 0.48 10.4 5.6 0.45 10.5 4.1 1.7 1 1 0 2 2 2 0 Protein of unknown function DUF45 Histidinol_dh PF00815.20 CCD22203.1 - 1.8e-160 534.4 0.5 2.6e-160 533.9 0.5 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 CCD22203.1 - 4.8e-27 93.6 0.1 1e-26 92.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 CCD22203.1 - 3.2e-14 53.1 0.2 3.2e-14 53.1 0.2 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase CAP_GLY PF01302.25 CCD22204.1 - 9.5e-15 54.4 0.1 2e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 CCD22204.1 - 0.0026 17.6 0.9 0.0046 16.8 0.9 1.4 1 0 0 1 1 1 1 CLIP1 zinc knuckle DUF1764 PF08576.10 CCD22204.1 - 0.13 13.2 0.2 0.13 13.2 0.2 3.7 3 1 0 3 3 2 0 Eukaryotic protein of unknown function (DUF1764) DUF812 PF05667.11 CCD22204.1 - 0.23 10.3 36.2 3.9e+02 -0.4 35.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Lebercilin PF15619.6 CCD22204.1 - 0.42 10.3 38.2 0.34 10.6 20.2 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 CCD22204.1 - 0.7 10.3 35.6 0.95 9.9 16.3 2.3 1 1 1 2 2 2 0 Fez1 MscS_porin PF12795.7 CCD22204.1 - 0.72 9.4 33.9 0.032 13.8 3.8 2.8 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain PspA_IM30 PF04012.12 CCD22204.1 - 0.87 9.1 25.9 0.91 9.1 15.3 2.7 1 1 1 2 2 2 0 PspA/IM30 family Rotamase PF00639.21 CCD22204.1 - 3.3 8.7 8.5 2.8 8.9 0.5 3.0 2 2 1 3 3 3 0 PPIC-type PPIASE domain PRKG1_interact PF15898.5 CCD22204.1 - 3.7 8.5 39.7 0.22 12.4 1.5 4.3 4 1 1 5 5 4 0 cGMP-dependent protein kinase interacting domain WXG100 PF06013.12 CCD22204.1 - 4.6 7.5 9.2 9.2 6.6 1.0 3.1 3 0 0 3 3 3 0 Proteins of 100 residues with WXG APG6_N PF17675.1 CCD22204.1 - 7.3 7.1 41.4 18 5.8 18.8 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region SH3_9 PF14604.6 CCD22206.1 - 4.1e-06 26.5 0.0 9.1e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CCD22206.1 - 0.0034 17.0 0.0 0.015 14.9 0.0 2.1 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CCD22206.1 - 0.02 14.6 0.1 0.045 13.4 0.1 1.6 1 0 0 1 1 1 0 Variant SH3 domain MtrG PF04210.13 CCD22206.1 - 0.15 11.9 0.1 0.44 10.5 0.1 1.8 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G SKG6 PF08693.10 CCD22206.1 - 0.67 9.4 2.0 0.74 9.3 0.0 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Nitroreductase PF00881.24 CCD22207.1 - 1.1e-06 28.8 0.1 2.1e-06 27.9 0.1 1.4 1 1 0 1 1 1 1 Nitroreductase family KH_1 PF00013.29 CCD22207.1 - 0.0035 17.2 0.1 0.0055 16.5 0.1 1.3 1 0 0 1 1 1 1 KH domain Nitroreductase PF00881.24 CCD22208.1 - 1.5e-06 28.4 0.0 2.6e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 Nitroreductase family Sars6 PF12133.8 CCD22209.1 - 0.0022 17.9 0.1 0.0034 17.3 0.1 1.3 1 0 0 1 1 1 1 Open reading frame 6 from SARS coronavirus Per1 PF04080.13 CCD22210.1 - 1.4e-84 283.8 21.9 2.1e-84 283.3 21.9 1.2 1 0 0 1 1 1 1 Per1-like family DUF5379 PF17350.2 CCD22210.1 - 0.15 12.3 0.2 0.15 12.3 0.2 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5379) Spindle_Spc25 PF08234.12 CCD22211.1 - 6.8e-19 67.8 0.4 6.8e-19 67.8 0.4 2.4 3 0 0 3 3 2 1 Chromosome segregation protein Spc25 Seryl_tRNA_N PF02403.22 CCD22211.1 - 0.0028 17.9 3.6 0.0028 17.9 3.6 2.8 2 1 1 3 3 3 1 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 CCD22211.1 - 0.0035 16.3 16.2 0.0052 15.7 16.2 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein APG6_N PF17675.1 CCD22211.1 - 0.0076 16.8 12.8 0.0076 16.8 12.8 2.5 2 1 1 3 3 3 1 Apg6 coiled-coil region Laminin_II PF06009.12 CCD22211.1 - 0.018 15.0 5.6 0.018 15.0 5.6 1.9 1 1 1 2 2 2 0 Laminin Domain II KASH_CCD PF14662.6 CCD22211.1 - 0.032 14.1 19.0 0.05 13.4 19.0 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Nup54 PF13874.6 CCD22211.1 - 0.13 12.4 14.1 0.7 10.0 14.1 2.1 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 SPATA24 PF15175.6 CCD22211.1 - 0.43 10.5 16.9 0.79 9.6 16.9 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Prominin PF05478.11 CCD22211.1 - 0.5 8.3 9.3 0.67 7.8 9.3 1.2 1 0 0 1 1 1 0 Prominin DASH_Dam1 PF08653.10 CCD22211.1 - 0.64 9.9 4.0 3.4 7.5 0.4 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF848 PF05852.11 CCD22211.1 - 0.67 10.1 15.5 0.81 9.8 3.5 2.3 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) zf-C4H2 PF10146.9 CCD22211.1 - 0.75 10.1 13.4 0.98 9.7 13.4 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein FAT PF02259.23 CCD22211.1 - 1.7 7.8 10.3 0.093 11.9 3.5 1.9 1 1 1 2 2 2 0 FAT domain CENP-F_leu_zip PF10473.9 CCD22211.1 - 2 8.4 23.0 40 4.2 21.6 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 CCD22211.1 - 2 7.4 13.8 3.6 6.6 13.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 CCD22211.1 - 2.6 8.5 11.2 7.4 7.1 0.6 3.0 2 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.19 CCD22211.1 - 2.9 5.7 11.1 3.7 5.3 11.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.6 CCD22211.1 - 3.2 7.1 28.1 3.8 6.8 23.9 2.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Spc24 PF08286.11 CCD22211.1 - 4.2 7.7 18.8 2.9 8.2 4.2 3.0 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 PdaC PF13739.6 CCD22211.1 - 4.3 8.4 8.7 3.3 8.7 0.8 3.0 1 1 1 2 2 2 0 Deacetylase PdaC UPF0242 PF06785.11 CCD22211.1 - 6.3 6.9 24.2 61 3.6 24.2 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exo_endo_phos PF03372.23 CCD22212.1 - 3.6e-13 49.6 0.0 5e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2207 PF09972.9 CCD22212.1 - 0.0015 17.4 0.1 0.0022 16.9 0.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Yip1 PF04893.17 CCD22212.1 - 0.006 16.3 7.1 0.012 15.3 7.1 1.4 1 0 0 1 1 1 1 Yip1 domain PsbX PF06596.11 CCD22212.1 - 0.014 15.4 3.4 0.035 14.1 3.4 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Phage_holin_3_6 PF07332.11 CCD22212.1 - 0.27 11.3 0.9 0.45 10.6 0.9 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Glyco_transf_28 PF03033.20 CCD22213.1 - 2.2e-32 112.0 0.0 6.5e-32 110.5 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 CCD22213.1 - 6.1e-27 93.8 3.1 2.7e-23 82.0 0.1 4.0 2 1 1 3 3 3 2 GRAM domain UDPGT PF00201.18 CCD22213.1 - 1.1e-08 34.4 0.0 2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 CCD22213.1 - 2.2e-06 28.1 0.2 2.6e-05 24.7 0.2 2.9 2 0 0 2 2 2 1 PH domain Glyco_tran_28_C PF04101.16 CCD22213.1 - 0.0039 17.2 0.0 0.049 13.6 0.0 2.5 1 1 1 2 2 2 1 Glycosyltransferase family 28 C-terminal domain PH_11 PF15413.6 CCD22213.1 - 0.21 12.0 2.9 0.27 11.7 0.1 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain ABC_membrane PF00664.23 CCD22214.1 - 1.2e-59 202.2 7.0 1.6e-59 201.8 7.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CCD22214.1 - 5.4e-30 104.7 0.0 1.3e-29 103.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CCD22214.1 - 5.6e-06 26.0 0.8 0.001 18.6 0.8 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CCD22214.1 - 0.0012 19.2 0.1 0.0042 17.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CCD22214.1 - 0.0016 18.2 0.0 0.0047 16.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 CCD22214.1 - 0.0034 16.2 0.0 0.0055 15.6 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 CCD22214.1 - 0.0083 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.17 CCD22214.1 - 0.011 15.8 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 CCD22214.1 - 0.013 16.0 0.0 0.2 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CCD22214.1 - 0.015 15.6 0.1 0.092 13.0 0.1 2.3 1 1 0 1 1 1 0 AAA domain Phage_int_SAM_1 PF02899.17 CCD22214.1 - 0.016 15.5 1.5 0.068 13.5 0.5 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain AAA_33 PF13671.6 CCD22214.1 - 0.017 15.3 0.0 0.088 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CCD22214.1 - 0.058 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CCD22214.1 - 0.08 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 CCD22214.1 - 0.14 12.0 1.8 0.76 9.5 0.3 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system PH PF00169.29 CCD22215.1 - 9.7e-07 29.3 0.6 2.2e-06 28.1 0.1 1.9 2 0 0 2 2 2 1 PH domain IDH PF03971.14 CCD22215.1 - 0.019 13.4 0.0 0.033 12.7 0.0 1.2 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase BLOC1_2 PF10046.9 CCD22215.1 - 0.12 12.6 0.6 0.32 11.3 0.6 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosomal_L37e PF01907.19 CCD22216.1 - 4.2e-27 94.1 10.8 7.2e-27 93.3 10.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 CCD22216.1 - 0.0072 16.3 1.3 0.011 15.7 1.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.18 CCD22216.1 - 0.025 14.6 0.6 0.03 14.4 0.6 1.3 1 1 0 1 1 1 0 SelR domain DUF1258 PF06869.12 CCD22216.1 - 1.2 8.6 4.6 0.68 9.4 2.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) FHA PF00498.26 CCD22217.1 - 2.2e-08 34.3 0.6 9.1e-08 32.3 0.1 2.5 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CCD22217.1 - 0.00067 19.9 0.1 0.038 14.3 0.0 3.2 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain Swi6_N PF18530.1 CCD22218.1 - 1.8e-35 121.3 1.0 8.3e-35 119.2 0.1 2.6 2 0 0 2 2 2 1 Swi6 N-terminal domain Ank_2 PF12796.7 CCD22218.1 - 6.3e-11 42.7 2.7 0.00017 22.1 0.2 2.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CCD22218.1 - 1.3e-10 40.5 0.7 0.00031 20.9 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CCD22218.1 - 6.8e-10 39.0 4.6 6.2e-05 23.2 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CCD22218.1 - 8.4e-07 29.2 1.2 0.079 13.4 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CCD22218.1 - 2.6e-06 27.9 0.5 0.035 14.7 0.0 4.3 2 2 2 4 4 4 2 Ankyrin repeats (many copies) HIP1_clath_bdg PF16515.5 CCD22218.1 - 0.0011 19.5 7.3 0.0021 18.6 6.1 2.2 1 1 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Phage_GPO PF05929.11 CCD22218.1 - 0.047 13.3 3.5 0.11 12.1 3.5 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase MSV199 PF10553.9 CCD22218.1 - 0.12 12.7 6.6 0.065 13.5 3.2 2.3 2 0 0 2 2 2 0 MSV199 domain DUF883 PF05957.13 CCD22218.1 - 1.4 9.6 4.0 0.76 10.4 1.3 2.1 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF883) Atg14 PF10186.9 CCD22218.1 - 6.2 5.8 11.8 13 4.7 11.8 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 CCD22218.1 - 7.2 6.1 10.6 24 4.3 10.6 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 CCD22218.1 - 8.9 6.7 10.3 8.8 6.7 6.1 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AA_permease PF00324.21 CCD22219.1 - 2.9e-140 468.0 47.1 3.3e-140 467.9 47.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD22219.1 - 3.8e-28 98.5 53.9 6.2e-28 97.8 53.9 1.3 1 1 0 1 1 1 1 Amino acid permease YrhC PF14143.6 CCD22219.1 - 1.4 9.1 7.8 5 7.3 0.7 3.9 3 0 0 3 3 3 0 YrhC-like protein Nitroreductase PF00881.24 CCD22220.1 - 4.1e-08 33.5 0.1 6.5e-08 32.8 0.1 1.4 1 1 0 1 1 1 1 Nitroreductase family Nitroreductase PF00881.24 CCD22221.1 - 1.4e-05 25.2 0.1 2.4e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 Nitroreductase family AA_permease PF00324.21 CCD22222.1 - 3e-131 438.3 33.7 3.5e-131 438.1 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD22222.1 - 3.4e-33 115.1 32.6 4e-33 114.9 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease Colicin_im PF03857.13 CCD22222.1 - 0.17 11.8 1.3 0.48 10.4 1.3 1.7 1 0 0 1 1 1 0 Colicin immunity protein Rad60-SLD PF11976.8 CCD22223.1 - 1.3e-18 66.6 0.1 1.8e-18 66.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CCD22223.1 - 4.4e-13 48.8 0.0 5.3e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.25 CCD22224.1 - 2e-71 240.4 0.0 2.6e-70 236.8 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22224.1 - 1.8e-36 125.7 0.0 5.1e-36 124.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 CCD22224.1 - 3.7e-33 113.7 0.3 3.7e-33 113.7 0.3 2.0 2 0 0 2 2 2 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 CCD22224.1 - 1.4e-05 24.6 0.0 4.4e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCD22224.1 - 2.5 8.0 4.1 0.58 10.0 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Homeodomain PF00046.29 CCD22225.1 - 9.5e-14 51.0 1.0 1.6e-13 50.3 1.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CCD22225.1 - 1.3e-05 25.0 0.1 2.1e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 CCD22225.1 - 0.062 12.8 0.3 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez RNase_H2_suC PF08615.11 CCD22226.1 - 8e-06 26.1 0.2 5.2e-05 23.5 0.2 1.9 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DnaI_N PF07319.11 CCD22226.1 - 0.036 14.7 0.4 0.07 13.8 0.4 1.5 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus MTS PF05175.14 CCD22226.1 - 0.098 12.2 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RasGEF PF00617.19 CCD22227.1 - 1.5e-42 145.8 4.9 1.5e-42 145.8 4.9 2.9 4 0 0 4 4 4 1 RasGEF domain RasGEF_N PF00618.20 CCD22227.1 - 4.6e-15 55.7 1.2 4.6e-15 55.7 1.2 4.8 6 1 0 6 6 6 1 RasGEF N-terminal motif SH3_1 PF00018.28 CCD22227.1 - 8.2e-07 28.5 0.2 2.3e-06 27.1 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CCD22227.1 - 0.0015 18.2 0.1 0.021 14.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 CCD22227.1 - 0.012 15.5 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Variant SH3 domain ORC_WH_C PF18137.1 CCD22227.1 - 5.6 7.0 9.0 16 5.5 1.3 2.6 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal SPX PF03105.19 CCD22228.1 - 1.6e-47 163.2 29.8 2.5e-47 162.7 29.8 1.3 1 0 0 1 1 1 1 SPX domain CitMHS PF03600.16 CCD22228.1 - 3.9e-22 78.8 39.7 7.8e-22 77.8 38.5 1.8 1 1 0 1 1 1 1 Citrate transporter Na_sulph_symp PF00939.19 CCD22228.1 - 9.9e-20 71.0 30.2 1.3e-19 70.6 30.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region PfkB PF00294.24 CCD22229.1 - 1.4e-45 155.9 1.6 4.6e-45 154.2 1.6 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CCD22229.1 - 0.051 12.9 1.5 1.5 8.1 0.2 2.7 2 1 0 2 2 2 0 Phosphomethylpyrimidine kinase RNase_PH PF01138.21 CCD22230.1 - 4.8e-24 85.4 0.7 1.9e-22 80.2 0.2 2.8 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 ELO PF01151.18 CCD22231.1 - 4e-59 200.1 21.9 5.2e-59 199.8 21.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Myb_DNA-binding PF00249.31 CCD22232.1 - 6.5e-17 61.5 0.0 4.5e-07 29.9 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCD22232.1 - 9.8e-06 25.7 3.4 0.044 14.0 0.5 3.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain UPF0167 PF03691.14 CCD22232.1 - 0.094 12.5 0.3 0.25 11.1 0.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) SANT_DAMP1_like PF16282.5 CCD22232.1 - 0.63 10.3 6.1 18 5.6 0.1 2.6 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 CCD22232.1 - 1.9 8.5 15.7 0.036 14.0 1.7 4.1 3 0 0 3 3 3 0 Myb DNA-binding like Beach PF02138.18 CCD22233.1 - 1.4e-119 398.6 1.0 2.7e-119 397.6 1.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CCD22233.1 - 3.9e-08 33.3 0.5 4.2e-07 30.0 0.1 2.9 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Ribosomal_S11 PF00411.19 CCD22234.1 - 5.1e-46 155.6 2.3 6.3e-46 155.3 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L39 PF00832.20 CCD22235.1 - 1.9e-21 75.4 12.6 2.3e-21 75.1 12.6 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Mannosyl_trans3 PF11051.8 CCD22236.1 - 2.5e-81 273.1 0.0 3.7e-81 272.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative SSB PF00436.25 CCD22237.1 - 5.2e-19 68.2 0.0 6.7e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family MFS_1 PF07690.16 CCD22238.1 - 3.2e-28 98.7 17.8 4.3e-28 98.2 17.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CCD22238.1 - 6.6e-05 22.4 2.7 0.00059 19.2 0.2 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF63 PF01889.17 CCD22238.1 - 0.057 13.6 2.4 0.072 13.3 0.7 2.0 1 1 0 2 2 2 0 Membrane protein of unknown function DUF63 DUF3792 PF12670.7 CCD22238.1 - 0.24 11.6 6.1 0.059 13.5 1.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) Pox_A14 PF05767.12 CCD22238.1 - 7.6 6.8 8.3 5.1 7.3 1.7 3.4 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Cbl_N2 PF02761.14 CCD22239.1 - 0.43 11.3 3.3 3.5 8.4 0.0 3.4 3 0 0 3 3 3 0 CBL proto-oncogene N-terminus, EF hand-like domain Ribosomal_L22 PF00237.19 CCD22240.1 - 5.5e-38 129.3 0.2 5.5e-38 129.3 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e CRT10 PF08728.10 CCD22240.1 - 0.069 11.3 0.2 0.072 11.3 0.2 1.0 1 0 0 1 1 1 0 CRT10 Fis1_TPR_C PF14853.6 CCD22240.1 - 0.078 13.1 0.1 25 5.1 0.0 2.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat CASP_C PF08172.12 CCD22241.1 - 1.2e-66 224.6 7.8 1.2e-66 224.6 7.8 4.5 2 1 0 3 3 3 1 CASP C terminal Jnk-SapK_ap_N PF09744.9 CCD22241.1 - 0.0031 17.7 7.8 0.0031 17.7 7.8 5.7 3 1 1 5 5 5 2 JNK_SAPK-associated protein-1 YojJ PF10372.9 CCD22241.1 - 0.28 11.3 6.6 2.2 8.4 0.1 3.9 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus Leu_zip PF15294.6 CCD22241.1 - 1.3 8.4 73.8 0.88 9.0 2.8 5.0 3 1 1 4 4 4 0 Leucine zipper STE3 PF02076.15 CCD22242.1 - 3.5e-86 289.0 23.8 4.2e-86 288.8 23.8 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF2516 PF10724.9 CCD22242.1 - 0.82 10.0 0.0 0.82 10.0 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2516) Helicase_C PF00271.31 CCD22243.1 - 3.9e-15 56.1 0.0 9.3e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2401 PF10287.9 CCD22244.1 - 2.4e-84 282.5 2.1 3.6e-84 281.9 2.1 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CCD22244.1 - 1.1e-24 86.6 0.0 2.3e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Longin_2 PF18639.1 CCD22245.1 - 1.6e-66 223.2 0.6 3.3e-66 222.2 0.6 1.6 1 0 0 1 1 1 1 Yeast longin domain POX PF07526.11 CCD22245.1 - 0.28 11.8 3.8 0.18 12.4 0.5 2.4 2 0 0 2 2 2 0 Associated with HOX Zip PF02535.22 CCD22246.1 - 1.5e-26 93.4 13.7 3.8e-15 56.0 4.5 2.4 2 1 0 2 2 2 2 ZIP Zinc transporter DUF3899 PF13038.6 CCD22246.1 - 0.06 13.9 1.7 0.31 11.6 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3899) Mem_trans PF03547.18 CCD22246.1 - 0.077 11.4 2.7 0.22 9.9 2.6 1.7 1 1 0 1 1 1 0 Membrane transport protein AA_permease PF00324.21 CCD22247.1 - 4.9e-85 285.9 40.8 6.2e-85 285.6 40.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD22247.1 - 8.5e-39 133.6 46.8 1.2e-38 133.1 46.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1129 PF06570.11 CCD22247.1 - 0.007 15.9 2.9 0.007 15.9 2.9 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1129) GTP_EFTU PF00009.27 CCD22248.1 - 9.4e-39 133.0 0.0 1.4e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CCD22248.1 - 3.9e-17 62.1 0.0 8.8e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFTUD2 PF16004.5 CCD22248.1 - 1.4e-14 54.7 5.6 1.4e-14 54.7 5.6 1.8 2 0 0 2 2 2 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 CCD22248.1 - 1.2e-12 47.7 0.0 2.5e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 CCD22248.1 - 4.5e-08 33.4 0.0 1.2e-07 32.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCD22248.1 - 4.8e-07 29.9 0.1 2.6e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase EFG_II PF14492.6 CCD22248.1 - 0.0029 17.6 0.0 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II Dynamin_N PF00350.23 CCD22248.1 - 0.015 15.3 0.1 4.8 7.2 0.0 2.6 1 1 1 2 2 2 0 Dynamin family Ras PF00071.22 CCD22248.1 - 0.054 13.1 0.1 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Ras family Roc PF08477.13 CCD22248.1 - 0.12 12.6 0.0 29 4.9 0.0 2.6 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase polyprenyl_synt PF00348.17 CCD22249.1 - 3.8e-95 317.8 0.1 4.6e-95 317.5 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Pkinase PF00069.25 CCD22250.1 - 5.5e-40 137.4 0.0 1e-22 80.8 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22250.1 - 2.9e-21 75.9 0.0 1.7e-14 53.8 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Ribosomal_L14 PF00238.19 CCD22251.1 - 5.2e-41 139.6 2.0 5.9e-41 139.4 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Glyco_transf_56 PF07429.11 CCD22251.1 - 0.18 10.9 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 Pkinase PF00069.25 CCD22252.1 - 5.4e-43 147.2 1.7 9.1e-42 143.2 1.7 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22252.1 - 6.3e-20 71.5 0.0 1.3e-19 70.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CCD22252.1 - 0.14 11.5 1.0 0.23 10.8 0.2 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCD22252.1 - 0.2 11.6 0.1 0.33 10.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family L51_S25_CI-B8 PF05047.16 CCD22253.1 - 5.4e-14 51.8 0.1 1e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Pkinase PF00069.25 CCD22254.1 - 1.5e-71 240.9 0.0 2.4e-71 240.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22254.1 - 2e-40 138.7 0.0 2.9e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD22254.1 - 3.5e-05 23.2 0.0 5.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CCD22254.1 - 0.028 13.4 0.2 0.041 12.8 0.2 1.4 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CCD22254.1 - 0.098 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.16 CCD22255.1 - 7.5e-20 71.2 16.9 3.9e-13 49.1 10.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily RPAP1_N PF08621.10 CCD22255.1 - 0.1 12.4 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 RPAP1-like, N-terminal PigN PF04987.14 CCD22256.1 - 5.6e-128 427.6 51.5 8.1e-128 427.1 51.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 CCD22256.1 - 1.4e-12 47.9 4.0 2.2e-10 40.7 3.9 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CCD22256.1 - 1.6e-10 40.9 0.0 3.2e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 CCD22256.1 - 3.4e-05 23.3 0.0 5.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily PIR PF00399.19 CCD22257.1 - 3.3e-73 239.9 136.5 7.7e-09 34.9 6.2 10.0 10 0 0 10 10 10 9 Yeast PIR protein repeat DUF2807 PF10988.8 CCD22257.1 - 0.61 9.9 23.8 2.4 7.9 8.9 2.2 1 1 1 2 2 2 0 Putative auto-transporter adhesin, head GIN domain TFIIA PF03153.13 CCD22257.1 - 4.9 7.0 22.9 5.8 6.8 22.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIR PF00399.19 CCD22258.1 - 5.9e-66 216.8 122.2 4.2e-09 35.7 2.7 10.6 7 3 3 10 10 10 9 Yeast PIR protein repeat DUF5544 PF17698.1 CCD22258.1 - 0.099 12.8 6.8 51 4.0 0.1 4.6 1 1 4 5 5 5 0 Family of unknown function (DUF5544) HTH_37 PF13744.6 CCD22258.1 - 0.25 11.3 5.0 33 4.5 0.2 3.6 1 1 3 4 4 4 0 Helix-turn-helix domain Vps35 PF03635.17 CCD22259.1 - 1.7e-264 879.8 31.9 2.2e-264 879.5 31.9 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF5534 PF17686.1 CCD22259.1 - 0.003 17.8 0.5 0.011 16.1 0.6 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5534) TetR_C_8 PF14278.6 CCD22259.1 - 0.086 12.9 2.4 0.22 11.6 0.3 2.9 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region peroxidase PF00141.23 CCD22260.1 - 3.5e-41 141.4 0.0 8.2e-41 140.2 0.0 1.6 1 1 0 1 1 1 1 Peroxidase Pam17 PF08566.10 CCD22261.1 - 2.1e-67 226.1 0.0 2.5e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF1086 PF06461.11 CCD22261.1 - 0.02 14.8 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) Zn_clus PF00172.18 CCD22262.1 - 8.6e-07 29.0 10.2 2e-06 27.8 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIEAP PF16026.5 CCD22262.1 - 0.12 12.5 2.4 0.32 11.2 2.4 1.7 1 0 0 1 1 1 0 Mitochondria-eating protein Las1 PF04031.13 CCD22263.1 - 4.4e-43 147.0 0.2 4.4e-43 147.0 0.2 1.9 2 0 0 2 2 2 1 Las1-like PRP9_N PF16958.5 CCD22263.1 - 0.0072 16.4 4.6 0.0072 16.4 4.6 3.2 2 2 0 2 2 2 1 Pre-mRNA-splicing factor PRP9 N-terminus ATP-synt_F6 PF05511.11 CCD22263.1 - 0.019 15.4 0.7 0.067 13.6 0.7 2.0 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 RNA_polI_A34 PF08208.11 CCD22264.1 - 1.4e-24 87.3 12.5 1.4e-24 87.3 12.5 1.5 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 TFA2_Winged_2 PF18121.1 CCD22265.1 - 1.8e-20 72.4 1.2 5.3e-20 70.9 0.1 2.2 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 CCD22265.1 - 5.3e-16 58.7 0.7 1.4e-15 57.3 0.7 1.8 1 0 0 1 1 1 1 TFIIE beta subunit core domain LexA_DNA_bind PF01726.16 CCD22265.1 - 0.079 12.8 0.1 0.48 10.2 0.0 2.3 2 0 0 2 2 2 0 LexA DNA binding domain RNA_pol_Rpb4 PF03874.16 CCD22266.1 - 9.2e-33 113.2 18.7 1.5e-29 102.8 18.7 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 BUD22 PF09073.10 CCD22266.1 - 0.0049 16.3 11.0 0.0056 16.1 11.0 1.3 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.13 CCD22266.1 - 0.066 13.2 14.1 0.076 13.0 14.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rtf2 PF04641.12 CCD22266.1 - 0.15 11.4 9.0 0.2 11.0 9.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger SLC12 PF03522.15 CCD22266.1 - 1.5 7.7 12.4 2 7.4 12.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 XRN_M PF17846.1 CCD22266.1 - 1.9 7.3 9.4 2.4 7.0 9.4 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Androgen_recep PF02166.16 CCD22266.1 - 4 6.2 7.9 5.8 5.6 7.9 1.2 1 0 0 1 1 1 0 Androgen receptor FYDLN_acid PF09538.10 CCD22266.1 - 5.3 7.8 13.1 0.96 10.2 9.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) FAM76 PF16046.5 CCD22266.1 - 7.9 5.7 15.1 0.38 10.1 9.7 1.5 2 0 0 2 2 2 0 FAM76 protein DUF3464 PF11947.8 CCD22266.1 - 8.6 6.1 7.8 18 5.1 7.8 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Glyco_transf_15 PF01793.16 CCD22267.1 - 3.4e-73 246.8 15.1 5.3e-57 193.5 10.0 2.1 1 1 1 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Metallophos PF00149.28 CCD22268.1 - 6.3e-11 43.2 1.6 1.1e-10 42.4 1.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GTA_holin_3TM PF11351.8 CCD22268.1 - 0.069 13.7 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Orf78 PF06024.12 CCD22268.1 - 0.3 11.4 7.0 3 8.2 0.1 2.6 3 0 0 3 3 3 0 Orf78 (ac78) SAS4 PF15460.6 CCD22269.1 - 2.6e-32 110.9 3.2 1.1e-31 108.8 3.2 2.2 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Corazonin PF17308.2 CCD22269.1 - 0.46 10.9 5.4 0.12 12.7 1.3 2.2 2 0 0 2 2 2 0 Pro-corazonin Nipped-B_C PF12830.7 CCD22270.1 - 9.9e-35 120.2 3.3 6e-34 117.7 0.1 3.5 4 0 0 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 CCD22270.1 - 8.8e-16 57.9 1.4 1e-13 51.3 1.1 2.9 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Alba PF01918.21 CCD22270.1 - 0.021 14.7 2.6 6.7 6.6 0.1 3.5 3 0 0 3 3 3 0 Alba HEAT PF02985.22 CCD22270.1 - 0.23 11.8 0.7 96 3.7 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat DUF1798 PF08807.10 CCD22270.1 - 4 7.6 10.0 9 6.5 0.5 3.6 4 0 0 4 4 4 0 Bacterial domain of unknown function (DUF1798) PXA PF02194.15 CCD22271.1 - 9.2e-16 58.3 2.8 8e-15 55.3 2.8 2.6 1 1 0 1 1 1 1 PXA domain PCI PF01399.27 CCD22272.1 - 0.0021 18.5 0.4 0.003 18.0 0.4 1.4 1 0 0 1 1 1 1 PCI domain CybS PF05328.12 CCD22273.1 - 1.3e-48 164.1 0.0 1.6e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit UQ_con PF00179.26 CCD22274.1 - 5.2e-44 149.3 0.0 7e-44 148.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 CCD22274.1 - 1.3e-27 95.3 1.6 2.3e-27 94.6 1.6 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Ada3 PF10198.9 CCD22275.1 - 1.9e-42 144.6 3.2 1.9e-42 144.6 3.2 3.4 3 1 0 3 3 3 1 Histone acetyltransferases subunit 3 TMEM43 PF07787.12 CCD22275.1 - 2.5 7.4 6.6 5.6 6.3 6.6 1.5 1 0 0 1 1 1 0 Transmembrane protein 43 MRP-S28 PF10213.9 CCD22276.1 - 1.6e-48 164.3 7.9 1.1e-47 161.6 3.9 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal subunit protein VPS11_C PF12451.8 CCD22276.1 - 0.3 11.4 1.3 3.9 7.8 0.5 2.6 1 1 1 2 2 2 0 Vacuolar protein sorting protein 11 C terminal HMG_box PF00505.19 CCD22277.1 - 2.6e-11 43.8 4.0 2.6e-11 43.8 4.0 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCD22277.1 - 1.1e-07 32.3 2.9 1.1e-07 32.3 2.9 1.9 2 0 0 2 2 2 1 HMG-box domain DUF3086 PF11285.8 CCD22277.1 - 0.013 14.6 1.5 0.054 12.6 1.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3086) Transketolase_N PF00456.21 CCD22277.1 - 0.043 12.8 1.0 0.069 12.1 1.0 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain AP3D1 PF06375.11 CCD22277.1 - 2.2 8.5 17.5 2.1 8.6 15.8 1.9 1 1 1 2 2 2 0 AP-3 complex subunit delta-1 IPK PF03770.16 CCD22278.1 - 1.4e-53 181.8 3.1 1.9e-53 181.3 3.1 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase BSMAP PF12280.8 CCD22278.1 - 0.026 14.7 0.2 0.048 13.9 0.2 1.3 1 0 0 1 1 1 0 Brain specific membrane anchored protein PsbR PF04725.12 CCD22278.1 - 0.073 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR zf-CCCH_7 PF18586.1 CCD22278.1 - 0.15 12.4 0.3 2.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 DUF4611 PF15387.6 CCD22278.1 - 0.28 11.4 3.4 0.56 10.5 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) GCIP PF13324.6 CCD22278.1 - 0.3 10.7 3.5 0.54 9.8 3.5 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting YL1 PF05764.13 CCD22278.1 - 0.43 10.7 4.2 0.72 9.9 4.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 CCD22278.1 - 1.8 8.2 8.8 3.3 7.4 8.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GTP_EFTU PF00009.27 CCD22279.1 - 1.1e-44 152.4 0.0 1.1e-44 152.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CCD22279.1 - 2.7e-35 121.1 1.1 1e-34 119.2 1.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CCD22279.1 - 1.8e-08 34.6 1.0 1.8e-08 34.6 1.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCD22279.1 - 0.015 15.3 0.1 0.015 15.3 0.1 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase Peptidase_U32_C PF16325.5 CCD22279.1 - 0.086 13.1 0.1 0.32 11.3 0.1 2.0 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain TFIIA PF03153.13 CCD22279.1 - 0.83 9.6 42.4 1.2 9.0 42.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HSP20 PF00011.21 CCD22280.1 - 1.2e-11 44.7 0.1 1.2e-11 44.7 0.1 2.3 3 1 0 3 3 3 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CCD22280.1 - 6.5e-06 25.6 0.0 1.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA RR_TM4-6 PF06459.12 CCD22280.1 - 0.25 11.2 26.5 0.38 10.5 26.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 CCD22280.1 - 8.5 3.3 14.4 11 3.0 14.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sec7 PF01369.20 CCD22281.1 - 2.1e-70 236.1 0.0 8.3e-70 234.2 0.0 2.2 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CCD22281.1 - 3.8e-42 143.9 1.1 3.8e-42 143.9 1.1 3.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CCD22281.1 - 8.8e-29 99.2 18.5 2.4e-28 97.8 2.3 6.1 6 0 0 6 6 6 2 Domain of unknown function (DUF1981) DCB PF16213.5 CCD22281.1 - 9.9e-19 67.7 3.6 9.9e-19 67.7 3.6 3.7 3 1 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 AMP-binding PF00501.28 CCD22282.1 - 5.5e-85 285.5 0.0 6.8e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCD22282.1 - 3.1e-22 79.3 0.3 7.4e-22 78.1 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CCD22282.1 - 9.3e-20 70.3 0.5 2.3e-19 69.1 0.5 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus TIP41 PF04176.13 CCD22283.1 - 3.1e-62 209.1 5.3 4.6e-62 208.5 5.3 1.3 1 0 0 1 1 1 1 TIP41-like family Evr1_Alr PF04777.13 CCD22284.1 - 3.2e-06 27.5 0.2 1.1e-05 25.8 0.1 2.0 1 1 1 2 2 2 1 Erv1 / Alr family DUF3899 PF13038.6 CCD22284.1 - 0.33 11.5 0.1 0.33 11.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) RRP14 PF15459.6 CCD22284.1 - 0.58 10.8 6.3 2.2 9.0 2.2 2.8 3 0 0 3 3 3 0 60S ribosome biogenesis protein Rrp14 V-ATPase_H_N PF03224.14 CCD22286.1 - 2.3e-59 201.3 13.9 2.3e-59 201.3 13.9 1.8 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CCD22286.1 - 7.8e-42 142.1 0.3 7.8e-42 142.1 0.3 3.4 3 1 1 4 4 4 1 V-ATPase subunit H TMF_TATA_bd PF12325.8 CCD22286.1 - 0.11 12.8 9.7 0.2 11.9 1.0 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Gln-synt_C PF00120.24 CCD22287.1 - 3.5e-21 75.6 0.0 3.1e-16 59.3 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CCD22287.1 - 1.1e-13 50.7 0.0 1.9e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Actin PF00022.19 CCD22288.1 - 2.9e-54 184.2 0.2 4.8e-53 180.2 0.2 2.1 1 1 0 1 1 1 1 Actin tRNA-synt_His PF13393.6 CCD22289.1 - 1.2e-35 123.3 0.0 1.2e-34 120.0 0.0 2.0 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CCD22289.1 - 1.3e-12 47.7 0.0 2.8e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 CCD22289.1 - 0.0013 18.3 0.7 0.0044 16.6 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.20 CCD22289.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) zf-HC5HC2H_2 PF13832.6 CCD22290.1 - 1.1e-29 102.8 5.2 1.1e-29 102.8 5.2 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CCD22290.1 - 2e-27 95.3 3.4 2e-27 95.3 3.4 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CCD22290.1 - 9.3e-14 50.7 3.3 9.3e-14 50.7 3.3 2.8 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 CCD22290.1 - 9.4e-10 38.2 3.9 9.4e-10 38.2 3.9 2.6 2 0 0 2 2 2 1 PHD-finger EPL1 PF10513.9 CCD22290.1 - 1.7e-08 35.0 2.3 1.9e-08 34.9 0.2 2.0 2 0 0 2 2 2 1 Enhancer of polycomb-like C1_1 PF00130.22 CCD22290.1 - 0.11 12.4 0.2 0.11 12.4 0.2 2.7 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 CCD22290.1 - 2.2 7.9 13.1 0.034 13.8 3.3 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RRPl_C4 PF17026.5 CCD22290.1 - 4.4 7.5 9.2 21 5.3 8.6 2.4 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-RING-like PF08746.11 CCD22290.1 - 5.8 7.3 22.6 2.5 8.5 8.9 2.9 2 0 0 2 2 2 0 RING-like domain Arrestin_N PF00339.29 CCD22291.1 - 0.65 10.1 5.2 0.71 9.9 0.1 3.0 3 0 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain AA_permease PF00324.21 CCD22292.1 - 4.5e-116 388.3 41.0 5.5e-116 388.0 41.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD22292.1 - 1.3e-35 123.1 45.1 1.9e-35 122.6 45.1 1.1 1 0 0 1 1 1 1 Amino acid permease Adaptin_N PF01602.20 CCD22293.1 - 1e-85 288.3 25.3 1.5e-85 287.8 25.3 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CCD22293.1 - 2e-06 28.1 0.2 7.7e-06 26.2 0.2 2.1 1 0 0 1 1 1 1 Adaptin C-terminal domain Vac14_Fab1_bd PF12755.7 CCD22293.1 - 0.0004 20.9 3.1 0.025 15.2 0.2 3.7 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region zf-C2H2_8 PF15909.5 CCD22293.1 - 0.028 14.7 0.1 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc ribbon HEAT PF02985.22 CCD22293.1 - 0.055 13.7 0.1 23 5.6 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat Op_neuropeptide PF08035.11 CCD22293.1 - 0.45 10.4 2.4 30 4.6 0.1 3.4 3 0 0 3 3 3 0 Opioids neuropeptide zf-CCCH_7 PF18586.1 CCD22293.1 - 0.77 10.1 3.4 17 5.8 0.0 3.3 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 TB2_DP1_HVA22 PF03134.19 CCD22294.1 - 5.3e-26 90.4 4.2 8.4e-26 89.7 4.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Glyco_hydro_65m PF03632.15 CCD22295.1 - 2.2e-31 109.1 5.3 3.9e-30 105.0 1.6 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 CCD22295.1 - 1e-26 94.0 0.0 2.1e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 CCD22295.1 - 6.9e-05 22.7 0.1 0.00045 20.1 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain Peptidase_M56 PF05569.11 CCD22295.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF3671 PF12420.8 CCD22295.1 - 0.11 12.6 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function F5_F8_type_C PF00754.25 CCD22295.1 - 9.6 6.3 8.2 0.51 10.4 0.0 2.8 3 0 0 3 3 3 0 F5/8 type C domain Cyclin_C_2 PF16899.5 CCD22296.1 - 3.1e-30 104.6 0.4 1e-29 102.9 0.0 2.0 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 CCD22296.1 - 5.7e-10 39.0 0.8 1.3e-09 37.8 0.8 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Peptidase_M41 PF01434.18 CCD22297.1 - 6.7e-51 172.8 0.1 1.6e-50 171.7 0.1 1.7 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CCD22297.1 - 8.7e-41 139.4 0.0 2.7e-40 137.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCD22297.1 - 4.3e-08 32.8 0.0 1.2e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CCD22297.1 - 1.2e-05 25.7 0.4 0.00014 22.3 0.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCD22297.1 - 2.1e-05 24.8 0.0 0.13 12.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CCD22297.1 - 0.00057 19.2 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 CCD22297.1 - 0.0014 18.4 0.0 0.0069 16.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CCD22297.1 - 0.003 17.6 0.1 0.012 15.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CCD22297.1 - 0.0045 17.0 0.0 0.87 9.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CCD22297.1 - 0.023 14.4 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 CCD22297.1 - 0.029 13.9 0.8 0.81 9.2 0.4 2.4 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CCD22297.1 - 0.034 14.3 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CCD22297.1 - 0.052 12.9 0.3 0.12 11.8 0.3 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 CCD22297.1 - 0.08 12.3 0.0 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 KaiC TsaE PF02367.17 CCD22297.1 - 0.1 12.6 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CCD22297.1 - 0.16 12.5 0.1 0.36 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_M50B PF13398.6 CCD22297.1 - 0.24 11.0 0.3 0.49 10.0 0.3 1.4 1 0 0 1 1 1 0 Peptidase M50B-like TFIIF_alpha PF05793.12 CCD22297.1 - 0.3 9.6 4.3 0.46 9.0 4.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SPATA3 PF15662.5 CCD22297.1 - 0.35 11.5 14.2 0.75 10.4 14.2 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Pacs-1 PF10254.9 CCD22297.1 - 0.37 9.7 4.1 0.57 9.1 4.1 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein SR-25 PF10500.9 CCD22297.1 - 1.9 8.1 20.2 0.17 11.4 11.9 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TPP_enzyme_N PF02776.18 CCD22298.1 - 1.9e-32 112.2 0.0 3.1e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCD22298.1 - 6.6e-27 93.9 0.0 2.9e-26 91.8 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCD22298.1 - 3.1e-15 56.3 0.0 5.6e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 CCD22298.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DXP_synthase_N PF13292.6 CCD22298.1 - 0.071 12.3 0.0 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase ArfGap PF01412.18 CCD22299.1 - 1.9e-33 115.0 0.7 1.9e-33 115.0 0.7 3.0 3 1 1 4 4 4 1 Putative GTPase activating protein for Arf Motile_Sperm PF00635.26 CCD22302.1 - 7.6e-26 90.1 0.2 7.6e-26 90.1 0.2 2.4 1 1 0 2 2 2 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CCD22302.1 - 5.7e-05 23.3 0.1 0.00013 22.1 0.1 1.6 1 0 0 1 1 1 1 Transmembrane protein 131-like Plasmodium_Vir PF05795.11 CCD22302.1 - 0.0047 16.4 6.9 0.0061 16.0 6.9 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein DUF3439 PF11921.8 CCD22302.1 - 0.24 11.4 5.9 0.52 10.3 5.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 CCD22302.1 - 0.4 8.8 7.0 0.55 8.4 7.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 GREB1 PF15782.5 CCD22302.1 - 0.62 7.1 11.1 0.74 6.9 11.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Endostatin PF06482.11 CCD22302.1 - 2.5 7.5 9.9 3.7 6.9 9.9 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CDC27 PF09507.10 CCD22302.1 - 2.6 7.3 24.6 3.7 6.8 24.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MMR1 PF08505.10 CCD22302.1 - 4 7.7 23.6 6.7 6.9 23.6 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein EVI2A PF05399.11 CCD22302.1 - 6.7 6.2 15.6 1.9 8.0 11.9 1.8 2 1 1 3 3 3 0 Ectropic viral integration site 2A protein (EVI2A) Peptidase_M24 PF00557.24 CCD22303.1 - 1.5e-50 171.8 0.0 2e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 HtrL_YibB PF09612.10 CCD22303.1 - 0.013 15.0 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) Ribosomal_S21 PF01165.20 CCD22304.1 - 2e-09 37.0 0.3 4.6e-09 35.9 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S21 SH3_1 PF00018.28 CCD22305.1 - 2e-12 46.5 0.2 3.9e-12 45.6 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCD22305.1 - 8.7e-11 41.5 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCD22305.1 - 1.8e-08 33.9 0.0 3.9e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain TctB PF07331.11 CCD22305.1 - 0.0093 16.2 2.9 0.013 15.8 2.9 1.2 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family SH3_10 PF17902.1 CCD22305.1 - 0.025 14.6 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 SH3 domain DUF4234 PF14018.6 CCD22305.1 - 6.4 7.0 8.7 1.1 9.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) Ribosomal_L14 PF00238.19 CCD22306.1 - 1.3e-33 115.7 0.0 1.5e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e zf-C3HC4 PF00097.25 CCD22307.1 - 3.6e-09 36.3 9.9 6.4e-09 35.5 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CCD22307.1 - 1.4e-08 34.4 8.7 2.1e-08 33.9 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCD22307.1 - 4.7e-08 32.9 8.1 9.6e-08 31.9 8.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CCD22307.1 - 1.6e-07 31.6 10.8 2.5e-07 30.9 10.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CCD22307.1 - 9.9e-06 25.3 10.9 2.9e-05 23.8 11.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCD22307.1 - 4.4e-05 23.3 9.6 7.7e-05 22.6 9.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CCD22307.1 - 0.00011 22.0 9.0 0.00026 20.8 9.0 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CCD22307.1 - 0.0035 17.5 10.2 0.0068 16.5 10.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CCD22307.1 - 0.0078 16.2 4.9 0.013 15.5 4.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CCD22307.1 - 0.033 14.0 7.2 0.088 12.6 7.2 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE_2 PF02318.16 CCD22307.1 - 0.038 14.2 1.8 0.074 13.3 1.8 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_11 PF17123.5 CCD22307.1 - 0.29 10.9 10.9 0.24 11.2 7.2 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 CCD22307.1 - 0.61 10.4 6.9 2 8.8 7.0 1.8 1 1 1 2 2 2 0 RING-H2 zinc finger domain PH PF00169.29 CCD22308.1 - 1.9e-13 50.8 0.1 8.8e-13 48.7 0.0 2.2 2 0 0 2 2 2 1 PH domain SH3_1 PF00018.28 CCD22308.1 - 1.4e-12 47.0 0.8 2.6e-12 46.1 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SAM_2 PF07647.17 CCD22308.1 - 2e-11 43.8 0.0 7.6e-11 42.0 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 CCD22308.1 - 6.2e-09 35.6 0.3 1.2e-08 34.7 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 CCD22308.1 - 0.0011 19.3 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 CCD22308.1 - 0.0042 17.3 0.0 4.9 7.5 0.0 3.0 2 0 0 2 2 2 2 Pleckstrin homology domain LURAP PF14854.6 CCD22308.1 - 0.0064 16.4 0.0 0.03 14.3 0.0 2.2 1 0 0 1 1 1 1 Leucine rich adaptor protein SH3_2 PF07653.17 CCD22308.1 - 0.05 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain EMP70 PF02990.16 CCD22309.1 - 2.9e-150 501.4 17.0 3.9e-150 501.0 17.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 LSM PF01423.22 CCD22310.1 - 5e-17 61.4 0.1 9.3e-17 60.5 0.1 1.5 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CCD22310.1 - 1.4e-05 25.1 0.0 3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Pex14_N PF04695.13 CCD22310.1 - 0.83 10.3 6.8 1.1 9.9 6.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 CCD22310.1 - 4 6.1 6.7 5 5.8 6.7 1.1 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 CCD22311.1 - 3.7e-06 27.4 2.1 0.013 16.1 0.7 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) KilA-N PF04383.13 CCD22311.1 - 6.4e-06 26.0 0.1 6.2e-05 22.8 0.1 2.8 1 1 0 1 1 1 1 KilA-N domain Ank_4 PF13637.6 CCD22311.1 - 0.00034 21.1 1.2 0.78 10.4 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCD22311.1 - 0.00049 20.3 1.7 0.24 12.1 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CCD22311.1 - 0.00097 19.4 2.6 0.017 15.4 0.2 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CCD22311.1 - 0.0015 18.9 0.3 0.45 11.1 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat HEAT_EZ PF13513.6 CCD22312.1 - 1.4e-13 51.0 0.2 0.003 18.0 0.0 8.0 8 0 0 8 8 8 2 HEAT-like repeat IBN_N PF03810.19 CCD22312.1 - 1.5e-13 50.4 8.4 2e-10 40.4 0.0 5.3 6 0 0 6 6 6 2 Importin-beta N-terminal domain HEAT PF02985.22 CCD22312.1 - 4.3e-11 42.1 7.3 0.073 13.4 0.1 8.4 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 CCD22312.1 - 1e-10 41.9 0.9 0.43 11.0 0.2 6.7 5 2 2 7 7 7 3 HEAT repeats Cnd1 PF12717.7 CCD22312.1 - 0.00017 21.7 13.4 0.077 13.0 0.1 5.5 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 CCD22312.1 - 0.0025 17.6 2.8 1.6 8.5 0.0 4.8 5 1 1 6 6 6 1 rRNA processing/ribosome biogenesis G-alpha PF00503.20 CCD22312.1 - 0.0098 15.1 0.2 0.036 13.2 0.1 2.1 1 1 0 1 1 1 1 G-protein alpha subunit RICTOR_V PF14668.6 CCD22312.1 - 0.039 14.2 0.2 1.6 9.0 0.1 3.7 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Xpo1 PF08389.12 CCD22312.1 - 0.061 13.4 12.8 0.045 13.8 2.4 4.8 5 1 0 5 5 5 0 Exportin 1-like protein YqfQ PF14181.6 CCD22312.1 - 0.13 12.4 2.2 3.5 7.8 0.1 3.6 3 0 0 3 3 3 0 YqfQ-like protein LisH PF08513.11 CCD22313.1 - 0.0029 17.5 0.1 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 LisH WD40 PF00400.32 CCD22314.1 - 1.3e-18 67.0 6.7 5e-06 27.1 0.4 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD22314.1 - 4.1e-07 30.2 0.0 0.19 12.0 0.0 4.1 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCD22314.1 - 0.0046 15.7 0.1 0.88 8.1 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CCD22314.1 - 0.018 14.0 0.0 0.52 9.2 0.0 2.4 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MAM1 PF10434.9 CCD22315.1 - 1.3e-46 159.4 16.1 1.3e-46 159.4 16.1 1.9 2 0 0 2 2 2 1 Monopolin complex protein MAM1 Atg8 PF02991.16 CCD22316.1 - 1.6e-48 163.2 0.1 1.8e-48 163.0 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CCD22316.1 - 4.2e-07 30.3 0.0 5.2e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 AAA_23 PF13476.6 CCD22317.1 - 0.055 14.0 8.6 0.078 13.5 8.6 1.1 1 0 0 1 1 1 0 AAA domain Kelch_4 PF13418.6 CCD22317.1 - 0.084 12.9 0.3 9.3 6.3 0.1 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain Dynamin_N PF00350.23 CCD22317.1 - 0.12 12.4 2.5 0.3 11.1 2.5 1.7 1 1 0 1 1 1 0 Dynamin family HSP70 PF00012.20 CCD22318.1 - 7.4e-260 863.3 8.8 8.4e-260 863.1 8.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCD22318.1 - 3.7e-17 62.1 0.1 5e-16 58.4 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CCD22318.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 CCD22318.1 - 0.076 12.0 0.7 0.37 9.7 0.3 2.0 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 CCD22318.1 - 0.65 9.2 5.3 0.1 11.9 0.3 2.2 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase SWI-SNF_Ssr4 PF08549.10 CCD22318.1 - 1 7.9 7.5 0.69 8.5 0.0 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Golgin_A5 PF09787.9 CCD22318.1 - 1.6 8.1 8.0 1.2 8.5 4.7 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 AAR2 PF05282.11 CCD22319.1 - 4.3e-33 115.2 1.2 5.5e-33 114.8 1.2 1.0 1 0 0 1 1 1 1 AAR2 protein MAP70 PF07058.11 CCD22319.1 - 0.12 11.1 1.0 0.34 9.6 0.6 1.8 1 1 1 2 2 2 0 Microtubule-associated protein 70 Ribosomal_S8e PF01201.22 CCD22320.1 - 5.6e-57 191.7 1.7 6.6e-57 191.5 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e zf-CSL PF05207.13 CCD22321.1 - 4.6e-20 71.1 0.2 6.4e-20 70.6 0.2 1.2 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 CCD22321.1 - 0.00048 20.2 0.1 0.001 19.1 0.1 1.5 1 0 0 1 1 1 1 Zinc ribbon domain ADH_zinc_N_2 PF13602.6 CCD22322.1 - 6.3e-14 53.2 0.0 1.1e-13 52.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCD22322.1 - 8e-06 25.7 0.2 1.8e-05 24.6 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SplA PF11132.8 CCD22322.1 - 0.025 14.3 0.1 0.063 13.1 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator protein (SplA) UQ_con PF00179.26 CCD22323.1 - 3.4e-21 75.4 0.0 4.8e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CCD22323.1 - 0.11 12.8 1.1 0.24 11.7 0.2 1.8 1 1 1 2 2 2 0 RWD domain Prok-E2_B PF14461.6 CCD22323.1 - 0.19 11.4 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B Pribosyltran_N PF13793.6 CCD22324.1 - 1.6e-44 150.5 0.2 9.9e-43 144.8 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CCD22324.1 - 3.4e-36 125.0 0.9 7.4e-30 104.3 0.4 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CCD22324.1 - 2.9e-16 59.4 0.6 7.7e-16 58.0 0.6 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CCD22324.1 - 0.0023 17.4 0.1 0.0036 16.8 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF2007 PF09413.10 CCD22324.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein UCH PF00443.29 CCD22325.1 - 1.7e-55 188.3 37.9 1.7e-55 188.3 37.9 3.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCD22325.1 - 6.5e-11 42.4 54.3 2.7e-08 33.8 45.0 4.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rad51 PF08423.11 CCD22326.1 - 1.1e-127 424.6 0.0 1.3e-127 424.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CCD22326.1 - 1.7e-12 47.4 0.0 2.5e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CCD22326.1 - 4e-09 36.3 0.0 6.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 CCD22326.1 - 1.2e-08 35.4 0.2 2.7e-08 34.3 0.2 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 CCD22326.1 - 2.5e-05 23.8 0.0 5.7e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 CCD22326.1 - 0.0043 16.4 0.5 0.026 13.8 0.0 2.2 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain Proteasome PF00227.26 CCD22327.1 - 2.3e-41 141.4 0.0 2.8e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Mntp PF02659.15 CCD22328.1 - 0.0029 17.4 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 Putative manganese efflux pump GBR2_CC PF18455.1 CCD22328.1 - 0.08 13.1 0.6 0.14 12.3 0.6 1.4 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain RICTOR_N PF14664.6 CCD22329.1 - 1.4e-94 317.2 17.2 4.1e-94 315.6 17.2 1.8 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 CCD22329.1 - 1.1e-33 115.1 10.2 7e-30 102.9 0.1 6.7 7 1 1 8 8 8 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 CCD22329.1 - 7.3e-30 103.0 1.5 3.7e-28 97.6 0.3 4.3 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 CCD22329.1 - 2.5e-29 101.8 0.6 2.5e-29 101.8 0.6 3.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain ATG16 PF08614.11 CCD22329.1 - 0.0093 16.2 4.6 0.042 14.1 4.6 2.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DivIC PF04977.15 CCD22329.1 - 1 9.2 11.0 2.2 8.1 1.9 2.9 1 1 1 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 CCD22329.1 - 3 7.1 5.0 6.4 6.0 5.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IES5 PF17335.2 CCD22330.1 - 8.8e-49 164.5 2.9 9.9e-49 164.4 2.9 1.0 1 0 0 1 1 1 1 Ino80 complex subunit 5 BRE1 PF08647.11 CCD22330.1 - 0.038 14.0 0.6 0.052 13.6 0.6 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Meth_synt_2 PF01717.18 CCD22331.1 - 3.5e-149 496.5 0.0 4.6e-146 486.2 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CCD22331.1 - 1.4e-122 409.1 0.0 3.2e-116 388.2 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain RPN1_C PF18051.1 CCD22331.1 - 0.16 12.0 0.1 0.4 10.8 0.1 1.6 1 0 0 1 1 1 0 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal Chorismate_bind PF00425.18 CCD22332.1 - 6.9e-89 297.8 0.0 1.8e-88 296.5 0.0 1.6 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 CCD22332.1 - 2.5e-30 105.6 0.0 2.7e-28 99.0 0.0 3.4 4 0 0 4 4 4 1 Anthranilate synthase component I, N terminal region POR PF01558.18 CCD22332.1 - 0.03 14.4 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase DUF4150 PF13665.6 CCD22332.1 - 0.16 12.2 0.2 0.62 10.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4150) PP2C PF00481.21 CCD22333.1 - 5.2e-84 281.9 0.0 9.3e-84 281.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C DUF1836 PF08876.11 CCD22333.1 - 0.093 12.8 0.0 0.32 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) Myb_DNA-binding PF00249.31 CCD22335.1 - 3e-14 52.9 1.9 4.1e-11 42.9 0.2 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCD22335.1 - 1.3e-10 41.4 1.3 1e-08 35.3 0.4 3.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain RRM_1 PF00076.22 CCD22336.1 - 2.2e-07 30.6 0.0 5.2e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec61_beta PF03911.16 CCD22337.1 - 3.5e-16 58.9 3.2 4.4e-16 58.6 3.2 1.1 1 0 0 1 1 1 1 Sec61beta family tRNA-synt_2b PF00587.25 CCD22338.1 - 1.1e-35 123.2 0.0 1.9e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PALP PF00291.25 CCD22339.1 - 8.4e-77 258.5 0.3 1.1e-76 258.0 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 CCD22339.1 - 4.7e-41 138.5 0.0 5.3e-26 90.2 0.0 2.7 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase FAD-oxidase_C PF02913.19 CCD22341.1 - 1e-59 202.2 0.0 1.4e-59 201.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CCD22341.1 - 4.1e-36 123.8 0.0 9.6e-36 122.6 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain DUF3602 PF12223.8 CCD22343.1 - 1.6e-15 57.4 20.1 6.2e-09 36.3 0.1 3.7 3 1 1 4 4 4 3 Protein of unknown function (DUF3602) GATase_2 PF00310.21 CCD22344.1 - 4.8e-167 555.9 0.0 8.2e-167 555.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 CCD22344.1 - 5.9e-153 509.4 0.0 9.1e-153 508.7 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 CCD22344.1 - 2e-109 365.4 0.0 1.8e-107 359.0 0.0 2.5 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 CCD22344.1 - 9.3e-71 237.4 3.9 1.8e-70 236.4 3.9 1.5 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 CCD22344.1 - 1.9e-24 86.4 0.5 2e-23 83.1 0.5 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 CCD22344.1 - 1e-22 80.0 0.1 2e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 CCD22344.1 - 1.2e-08 35.1 0.0 3e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CCD22344.1 - 1.4e-07 31.9 0.9 7.2e-05 23.3 0.0 3.4 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCD22344.1 - 1e-05 25.0 0.4 0.0083 15.4 0.0 3.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CCD22344.1 - 1.9e-05 24.1 0.0 4.7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 CCD22344.1 - 2.8e-05 23.0 0.1 2.8e-05 23.0 0.1 2.2 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 CCD22344.1 - 0.00025 20.3 0.0 0.00048 19.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CCD22344.1 - 0.00061 19.5 0.1 0.0025 17.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CCD22344.1 - 0.00075 19.0 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 CCD22344.1 - 0.0014 19.1 0.0 1.1 9.7 0.0 2.9 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 CCD22344.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 CCD22344.1 - 0.016 14.3 0.3 0.085 11.9 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A F420_oxidored PF03807.17 CCD22344.1 - 0.019 15.5 0.1 0.5 11.0 0.0 3.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FMO-like PF00743.19 CCD22344.1 - 0.02 13.3 0.4 1.9 6.8 0.0 2.9 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 CCD22344.1 - 0.041 13.1 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain IlvN PF07991.12 CCD22344.1 - 0.042 13.4 0.8 0.22 11.1 0.1 2.5 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GATase_6 PF13522.6 CCD22344.1 - 0.042 14.0 0.0 0.16 12.2 0.0 2.0 1 0 0 1 1 1 0 Glutamine amidotransferase domain AlaDh_PNT_C PF01262.21 CCD22344.1 - 0.057 12.7 0.2 11 5.2 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CCD22344.1 - 0.062 12.6 0.0 3.1 7.1 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 CCD22344.1 - 0.072 12.3 0.0 0.21 10.8 0.0 1.7 2 0 0 2 2 2 0 Thi4 family NAD_binding_2 PF03446.15 CCD22344.1 - 0.1 12.8 0.1 0.29 11.3 0.1 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 CCD22344.1 - 0.17 11.7 0.0 0.61 9.9 0.0 2.0 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 CCD22344.1 - 2 8.4 6.3 21 5.2 0.1 3.1 2 1 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Caf4 PF11615.8 CCD22345.1 - 0.051 13.5 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 CCR4-associated factor 4 DUF2357 PF09823.9 CCD22345.1 - 0.052 12.8 0.1 0.41 9.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2357) FixH PF05751.11 CCD22345.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 FixH Nop PF01798.18 CCD22346.1 - 4.4e-85 284.8 0.1 9e-85 283.8 0.1 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CCD22346.1 - 4e-21 75.2 0.3 1.3e-20 73.5 0.3 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain CDC27 PF09507.10 CCD22346.1 - 0.019 14.4 19.0 0.024 14.0 19.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.12 CCD22346.1 - 0.31 10.8 16.9 0.52 10.1 16.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CCD22346.1 - 1.2 7.4 20.0 1.6 6.9 20.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 CCD22346.1 - 2.5 8.2 32.8 4 7.5 32.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RP-C_C PF11800.8 CCD22346.1 - 3.1 7.8 9.6 25 4.9 0.0 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region PcfK PF14058.6 CCD22346.1 - 4.3 7.6 20.4 7.9 6.8 20.4 1.4 1 0 0 1 1 1 0 PcfK-like protein Hid1 PF12722.7 CCD22346.1 - 8.3 4.4 10.0 13 3.7 10.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ADH_N PF08240.12 CCD22347.1 - 2e-22 79.2 2.2 2e-22 79.2 2.2 1.9 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCD22347.1 - 9.1e-22 77.4 0.2 1.6e-21 76.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CCD22347.1 - 0.0022 17.3 1.4 0.0036 16.6 1.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 CCD22347.1 - 0.0036 17.6 0.0 0.0063 16.8 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 CCD22347.1 - 0.0044 16.4 0.1 0.0075 15.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CCD22347.1 - 0.0058 16.2 0.1 0.037 13.6 0.1 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HycI PF01750.18 CCD22347.1 - 0.062 13.1 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase maturation protease TrkA_N PF02254.18 CCD22347.1 - 0.072 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 CCD22347.1 - 0.079 13.4 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding ADH_zinc_N_2 PF13602.6 CCD22347.1 - 0.089 13.8 0.0 0.19 12.8 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase zf-RanBP PF00641.18 CCD22348.1 - 1.2e-21 75.6 11.6 1.4e-10 40.3 2.7 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 CCD22348.1 - 7.9e-08 32.0 0.3 0.00016 21.5 0.0 3.4 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD22348.1 - 0.0012 18.9 0.0 0.0032 17.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif Importin_rep_3 PF18806.1 CCD22348.1 - 0.044 13.8 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Importin 13 repeat Rubredoxin PF00301.20 CCD22348.1 - 0.092 12.8 3.3 6.5 6.9 0.2 2.6 2 0 0 2 2 2 0 Rubredoxin DZR PF12773.7 CCD22348.1 - 0.23 11.5 9.0 2.3 8.3 0.6 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-MIZ PF02891.20 CCD22348.1 - 0.32 10.8 2.5 16 5.4 0.1 2.5 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger AAA_18 PF13238.6 CCD22349.1 - 7e-33 113.9 1.3 1.1e-32 113.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CCD22349.1 - 4e-07 30.5 0.0 1.6e-06 28.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 CCD22349.1 - 1.8e-05 25.1 0.0 3.7e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CCD22349.1 - 1.8e-05 24.5 0.1 0.21 11.2 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase AAA_16 PF13191.6 CCD22349.1 - 0.00025 21.5 0.0 0.00041 20.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 CCD22349.1 - 0.00069 19.1 0.0 0.0073 15.8 0.0 2.1 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 CCD22349.1 - 0.00097 19.4 0.1 0.0034 17.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain ADK PF00406.22 CCD22349.1 - 0.0017 18.5 0.1 0.75 9.9 0.0 2.3 2 0 0 2 2 2 2 Adenylate kinase RNA_helicase PF00910.22 CCD22349.1 - 0.0022 18.4 0.1 0.008 16.6 0.0 1.9 2 0 0 2 2 2 1 RNA helicase FtsK_SpoIIIE PF01580.18 CCD22349.1 - 0.003 17.0 0.1 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.6 CCD22349.1 - 0.0042 17.2 0.0 0.32 11.2 0.0 2.5 1 1 0 2 2 2 1 AAA domain dNK PF01712.19 CCD22349.1 - 0.0043 16.9 0.3 2.4 8.0 0.0 2.4 1 1 0 2 2 2 2 Deoxynucleoside kinase AAA_29 PF13555.6 CCD22349.1 - 0.0079 15.9 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 CCD22349.1 - 0.0089 16.0 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 CCD22349.1 - 0.012 14.9 0.0 0.04 13.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 CCD22349.1 - 0.019 15.5 0.1 0.28 11.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.21 CCD22349.1 - 0.025 13.9 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 CCD22349.1 - 0.027 14.4 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 NTPase MeaB PF03308.16 CCD22349.1 - 0.049 12.6 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 CCD22349.1 - 0.052 13.6 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CCD22349.1 - 0.076 13.1 1.6 1.1 9.2 1.6 2.6 1 1 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 CCD22349.1 - 0.081 13.4 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CCD22349.1 - 0.081 12.0 0.0 0.21 10.6 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein NOT2_3_5 PF04153.18 CCD22350.1 - 5.6e-30 104.1 2.3 7.3e-30 103.7 2.3 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family zf-Mss51 PF13824.6 CCD22351.1 - 2.5e-17 62.7 0.4 5.4e-17 61.6 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.11 CCD22351.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain DNA_ligase_A_M PF01068.21 CCD22352.1 - 3e-64 216.4 0.3 4.6e-64 215.8 0.3 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CCD22352.1 - 8.8e-45 153.1 0.1 1.8e-44 152.1 0.1 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CCD22352.1 - 4.4e-26 91.4 0.0 1.6e-25 89.5 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 CCD22352.1 - 3.5e-05 24.2 0.1 7.9e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 RNA ligase DNA_ligase_OB_2 PF14743.6 CCD22352.1 - 0.026 14.6 0.4 8.6 6.5 0.0 2.7 2 0 0 2 2 2 0 DNA ligase OB-like domain CENP-X PF09415.10 CCD22353.1 - 1.5e-19 70.1 3.7 2.6e-19 69.3 3.7 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X DEAD PF00270.29 CCD22354.1 - 2.5e-44 151.1 0.1 5e-44 150.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD22354.1 - 8.2e-30 103.4 1.8 1.4e-28 99.4 0.5 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Mif2_N PF15624.6 CCD22354.1 - 1.3 9.8 8.0 2.4 8.9 8.0 1.5 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Pkinase PF00069.25 CCD22355.1 - 2e-68 230.6 1.3 4.3e-68 229.5 1.3 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22355.1 - 1.5e-38 132.5 0.5 2.2e-37 128.7 0.1 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCD22355.1 - 4.4e-06 25.9 7.8 1.4e-05 24.2 7.8 1.9 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CCD22355.1 - 0.00029 19.7 0.2 0.00075 18.4 0.2 1.9 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CCD22355.1 - 0.0003 20.2 0.0 0.00053 19.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CCD22355.1 - 0.1 12.2 0.0 0.1 12.2 0.0 2.2 2 0 0 2 2 2 0 RIO1 family WD40 PF00400.32 CCD22357.1 - 4.3e-09 36.9 3.4 0.037 14.9 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD22357.1 - 0.0037 17.5 0.0 7.4 6.9 0.0 3.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain APH_6_hur PF04655.14 CCD22357.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Cyclin_N PF00134.23 CCD22358.1 - 1.2e-40 138.2 0.0 2.9e-40 136.9 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCD22358.1 - 3.6e-34 117.4 1.8 6.5e-33 113.4 0.0 2.5 2 1 0 2 2 2 1 Cyclin, C-terminal domain MutS_V PF00488.21 CCD22359.1 - 1.4e-46 158.9 0.0 2.8e-46 157.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CCD22359.1 - 3.9e-22 79.4 3.5 3.9e-22 79.4 3.5 2.2 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 CCD22359.1 - 0.0074 16.6 0.2 0.048 14.0 0.1 2.4 2 0 0 2 2 2 1 MutS family domain IV NACHT PF05729.12 CCD22359.1 - 0.016 15.2 0.2 0.97 9.3 0.2 2.7 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 CCD22359.1 - 0.16 11.7 0.0 0.46 10.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CCD22359.1 - 0.41 10.7 3.7 1.7 8.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain Sas10 PF09368.10 CCD22360.1 - 2.5e-29 101.6 11.0 2.5e-29 101.6 11.0 2.3 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CCD22360.1 - 0.0003 21.4 0.3 0.0003 21.4 0.3 3.3 3 1 0 3 3 3 1 Sas10/Utp3/C1D family DUF1179 PF06678.11 CCD22360.1 - 0.06 13.3 1.0 0.34 10.9 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) RNA_pol_Rpc4 PF05132.14 CCD22361.1 - 1.1e-21 77.8 7.9 1.1e-21 77.8 7.9 4.1 3 2 1 4 4 4 1 RNA polymerase III RPC4 Sigma54_CBD PF04963.13 CCD22361.1 - 0.19 11.6 4.4 0.17 11.7 1.5 2.1 1 1 1 2 2 2 0 Sigma-54 factor, core binding domain APG9 PF04109.16 CCD22362.1 - 1.1e-192 641.3 25.3 1.3e-192 641.1 25.4 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 MFS_1 PF07690.16 CCD22363.1 - 1.6e-08 33.9 39.1 5e-07 29.0 38.1 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCD22363.1 - 6.9e-06 25.2 10.6 6.9e-06 25.2 10.6 3.4 3 2 2 5 5 5 1 Sugar (and other) transporter Goodbye PF17109.5 CCD22363.1 - 0.029 14.8 0.1 0.061 13.8 0.1 1.5 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Nop14 PF04147.12 CCD22364.1 - 6.8e-164 547.4 81.6 1.5e-100 337.8 26.9 2.3 1 1 1 2 2 2 2 Nop14-like family DUF4018 PF13210.6 CCD22364.1 - 0.054 13.3 1.3 0.14 11.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4018) PCI PF01399.27 CCD22365.1 - 5.3e-22 78.3 0.1 5.3e-22 78.3 0.1 2.7 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 CCD22365.1 - 2.2e-15 56.5 3.7 5.9e-15 55.1 3.7 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF5099 PF17025.5 CCD22365.1 - 0.054 13.9 2.2 0.29 11.6 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5099) DUF2013 PF09431.10 CCD22366.1 - 1.6e-42 144.9 10.6 1.6e-42 144.9 10.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) RTT107_BRCT_5 PF16770.5 CCD22366.1 - 0.038 13.9 0.5 0.13 12.2 0.2 2.1 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain DUF4745 PF15923.5 CCD22366.1 - 0.041 13.9 0.1 0.54 10.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) Coatomer_WDAD PF04053.14 CCD22367.1 - 7.6e-132 440.5 3.8 1.2e-131 439.9 3.8 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 CCD22367.1 - 5.9e-78 262.4 0.1 8.6e-78 261.9 0.1 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CCD22367.1 - 1e-40 136.9 16.7 8.3e-08 32.8 0.2 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD22367.1 - 2.4e-14 53.4 1.4 2.6e-05 24.5 0.0 7.1 5 2 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCD22367.1 - 3.3e-06 26.0 3.8 0.23 10.0 0.1 4.1 3 1 1 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 CCD22367.1 - 0.00013 21.9 0.3 3.8 7.3 0.0 4.1 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A TPR_2 PF07719.17 CCD22367.1 - 0.13 12.4 1.8 0.48 10.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CCD22367.1 - 0.14 12.0 1.7 0.27 11.1 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CCD22367.1 - 0.6 10.5 5.7 6.9 7.2 0.4 4.1 2 1 1 3 3 3 0 Tetratricopeptide repeat ApbA_C PF08546.11 CCD22368.1 - 1.4e-23 83.5 0.1 2.3e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CCD22368.1 - 7.6e-18 64.6 0.0 1.1e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NitrOD2 PF18550.1 CCD22368.1 - 0.13 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Nitrososphaera output domain 2 DAO PF01266.24 CCD22368.1 - 0.31 10.6 0.4 0.44 10.1 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Cpn60_TCP1 PF00118.24 CCD22369.1 - 4.2e-146 487.4 10.4 4.7e-146 487.3 10.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HMD PF03201.16 CCD22369.1 - 0.065 13.5 0.1 0.56 10.5 0.0 2.5 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase BPL_N PF09825.9 CCD22370.1 - 1.2e-121 406.4 0.0 1.6e-121 406.0 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 CCD22370.1 - 3.4e-23 82.0 0.0 7.2e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 CCD22370.1 - 6.7e-11 41.9 0.1 1.8e-10 40.5 0.1 1.8 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain RNA_pol_Rpb1_1 PF04997.12 CCD22371.1 - 4.3e-114 381.0 0.1 8.9e-114 380.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 CCD22371.1 - 3.1e-107 358.0 0.1 4.6e-107 357.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CCD22371.1 - 5e-78 261.1 0.0 1.5e-77 259.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CCD22371.1 - 5.2e-63 212.3 0.4 1e-62 211.4 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 CCD22371.1 - 3.2e-47 159.9 3.5 6.9e-47 158.8 3.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 CCD22371.1 - 1.6e-45 154.8 0.0 4.3e-45 153.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CCD22371.1 - 7.8e-35 119.1 0.1 2.2e-34 117.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 CCD22371.1 - 6.8e-15 54.5 290.8 0.032 14.6 14.6 15.2 2 1 17 22 22 22 19 RNA polymerase Rpb1 C-terminal repeat DUF4123 PF13503.6 CCD22371.1 - 0.082 13.3 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) Scm3 PF10384.9 CCD22372.1 - 2e-21 75.5 1.2 4.5e-21 74.3 1.2 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 Sugar_tr PF00083.24 CCD22373.1 - 4.7e-128 427.9 29.8 5.7e-128 427.6 29.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD22373.1 - 6.4e-21 74.7 31.8 4.2e-15 55.5 10.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Arf PF00025.21 CCD22374.1 - 1.4e-77 259.1 0.0 1.7e-77 258.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCD22374.1 - 1.4e-14 54.3 0.2 3.1e-14 53.2 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CCD22374.1 - 3.5e-14 52.7 0.0 6.2e-14 51.9 0.0 1.4 2 0 0 2 2 2 1 Ras family SRPRB PF09439.10 CCD22374.1 - 1.2e-13 50.9 0.0 1.6e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CCD22374.1 - 9.3e-12 44.8 1.0 6e-08 32.2 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CCD22374.1 - 1.9e-09 37.2 0.0 2.9e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCD22374.1 - 3e-05 24.0 0.0 4.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 CCD22374.1 - 0.011 15.4 0.2 0.019 14.6 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 CCD22374.1 - 0.055 13.6 0.4 0.13 12.4 0.4 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CCD22374.1 - 0.064 13.8 0.1 0.12 12.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter 6PF2K PF01591.18 CCD22374.1 - 0.067 12.5 0.1 0.11 11.7 0.1 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.19 CCD22374.1 - 0.093 12.3 0.1 9.6 5.7 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 CCD22374.1 - 0.096 12.2 0.0 0.26 10.8 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCD22374.1 - 0.11 12.4 0.0 16 5.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 CCD22374.1 - 0.13 12.8 0.1 0.21 12.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CCD22374.1 - 0.15 11.5 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Ribosomal_L29 PF00831.23 CCD22375.1 - 1.4e-15 57.0 3.7 1.4e-15 57.0 3.7 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein Phage_sheath_1C PF17482.2 CCD22375.1 - 0.0086 16.0 0.8 0.015 15.3 0.8 1.4 1 0 0 1 1 1 1 Phage tail sheath C-terminal domain MRP-L47 PF06984.13 CCD22375.1 - 0.14 12.3 3.1 0.22 11.7 1.0 2.3 1 1 1 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF4972 PF16342.5 CCD22375.1 - 0.39 10.4 5.9 4.6 6.9 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) DUF3114 PF11311.8 CCD22375.1 - 0.48 9.9 5.2 0.54 9.8 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) DUF3644 PF12358.8 CCD22375.1 - 1.6 9.3 5.4 1.3 9.6 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3644) Rho_GDI PF02115.17 CCD22376.1 - 4e-62 209.5 3.6 4.6e-62 209.3 3.6 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.28 CCD22377.1 - 2.3e-34 119.7 0.4 3.5e-34 119.1 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ATP-synt_ab PF00006.25 CCD22378.1 - 3.6e-113 376.5 0.0 5.4e-113 375.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.16 CCD22378.1 - 4.1e-97 324.6 0.1 6.7e-97 323.9 0.1 1.4 1 0 0 1 1 1 1 Hom_end-associated Hint ATP-synt_ab_Xtn PF16886.5 CCD22378.1 - 4e-46 155.8 0.0 8.8e-46 154.7 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension Hom_end PF05204.14 CCD22378.1 - 1e-40 138.3 0.2 3e-37 127.2 0.1 2.5 2 0 0 2 2 2 2 Homing endonuclease ATP-synt_ab_N PF02874.23 CCD22378.1 - 2e-15 57.1 2.5 4.6e-15 55.9 2.5 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LAGLIDADG_3 PF14528.6 CCD22378.1 - 3.4e-05 24.1 0.1 0.03 14.6 0.0 2.7 2 0 0 2 2 2 2 LAGLIDADG-like domain Hint PF01079.20 CCD22378.1 - 4e-05 23.2 0.0 9.4e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.6 CCD22378.1 - 0.0012 19.2 0.1 0.0033 17.7 0.1 1.8 1 0 0 1 1 1 1 Hint domain Vint PF14623.6 CCD22378.1 - 0.043 13.6 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Hint-domain QVR PF17064.5 CCD22378.1 - 0.21 11.9 0.4 0.45 10.8 0.4 1.5 1 0 0 1 1 1 0 Sleepless protein Ribosomal_L41 PF05162.13 CCD22379.1 - 1.2e-10 41.2 26.3 1.3e-10 41.2 26.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 Augurin PF15187.6 CCD22380.1 - 0.026 14.7 1.7 0.043 14.0 0.3 2.2 2 0 0 2 2 2 0 Oesophageal cancer-related gene 4 MARVEL PF01284.23 CCD22380.1 - 0.046 13.8 3.1 0.084 12.9 3.1 1.4 1 0 0 1 1 1 0 Membrane-associating domain Vma12 PF11712.8 CCD22380.1 - 0.45 10.6 4.7 0.1 12.7 0.8 2.1 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cullin PF00888.22 CCD22381.1 - 2.4e-153 512.1 17.7 2.4e-153 512.1 17.7 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 CCD22381.1 - 3.9e-23 81.2 8.9 1.7e-22 79.2 1.0 4.3 4 0 0 4 4 4 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 CCD22381.1 - 0.0086 16.4 0.1 0.12 12.8 0.0 3.0 3 0 0 3 3 3 1 Penicillinase repressor Z1 PF10593.9 CCD22381.1 - 0.055 13.0 0.1 0.055 13.0 0.1 3.4 4 0 0 4 4 4 0 Z1 domain HMGL-like PF00682.19 CCD22382.1 - 2.1e-86 289.8 0.1 3.2e-86 289.2 0.1 1.3 1 0 0 1 1 1 1 HMGL-like SidE PF12252.8 CCD22382.1 - 0.047 11.2 0.0 0.065 10.8 0.0 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein Trp_syntA PF00290.20 CCD22382.1 - 0.081 11.7 0.0 7.7 5.3 0.0 2.4 2 0 0 2 2 2 0 Tryptophan synthase alpha chain FliG_N PF14842.6 CCD22382.1 - 0.095 13.3 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 FliG N-terminal domain IATP PF04568.12 CCD22383.1 - 3.7e-12 46.5 0.2 4.4e-12 46.3 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP FapA PF03961.13 CCD22383.1 - 0.01 14.4 0.2 0.01 14.4 0.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sec2p PF06428.11 CCD22383.1 - 0.028 14.4 4.6 0.036 14.0 4.6 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF2730 PF10805.8 CCD22383.1 - 0.046 13.8 0.4 0.066 13.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Glutaredoxin2_C PF04399.13 CCD22383.1 - 0.14 12.0 1.1 0.21 11.5 1.1 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain FbpA PF05833.11 CCD22383.1 - 1.5 7.5 8.9 0.36 9.5 4.3 1.8 1 1 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) DivIC PF04977.15 CCD22384.1 - 6.3 6.6 6.6 5.2 6.9 3.7 2.3 1 1 1 2 2 2 0 Septum formation initiator Cyclin_N PF00134.23 CCD22385.1 - 2.7e-15 56.2 0.0 5.5e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCD22385.1 - 2.8e-05 24.6 0.1 2.8e-05 24.6 0.1 2.4 2 1 0 2 2 2 1 Cyclin AAA PF00004.29 CCD22386.1 - 1e-98 326.9 0.0 2.8e-48 163.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCD22386.1 - 4.4e-25 87.2 6.7 1.2e-13 50.7 0.7 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 CCD22386.1 - 7.5e-19 67.7 0.4 2.1e-18 66.3 0.4 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 CCD22386.1 - 2.7e-14 53.6 0.0 6e-07 29.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CCD22386.1 - 3.3e-14 53.0 0.1 1.5e-05 24.8 0.0 3.2 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCD22386.1 - 8.9e-13 49.0 0.3 0.00023 21.6 0.1 4.6 3 2 0 3 3 2 2 AAA ATPase domain AAA_5 PF07728.14 CCD22386.1 - 1.1e-11 44.8 0.6 9.8e-06 25.6 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CCD22386.1 - 3.4e-11 43.5 0.0 1.1e-05 25.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CCD22386.1 - 3.1e-09 36.5 0.0 0.0016 17.8 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 CCD22386.1 - 3e-08 34.0 3.4 0.081 13.2 0.0 4.5 3 2 2 5 5 4 2 AAA domain CDC48_2 PF02933.17 CCD22386.1 - 3.7e-08 33.0 0.0 9.2e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.6 CCD22386.1 - 1.7e-07 31.3 0.0 0.024 14.7 0.0 3.3 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 CCD22386.1 - 2.2e-07 31.3 0.0 0.0091 16.4 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 CCD22386.1 - 3e-07 30.0 0.3 0.025 14.0 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ATPase PF06745.13 CCD22386.1 - 9e-07 28.5 1.0 0.26 10.6 0.0 3.8 2 1 0 3 3 3 2 KaiC Vps4_C PF09336.10 CCD22386.1 - 9.5e-07 28.7 1.7 5.6e-05 23.1 0.2 3.0 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 CCD22386.1 - 1e-06 28.6 0.0 0.031 14.0 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 CCD22386.1 - 4.1e-06 27.4 0.0 0.15 12.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CCD22386.1 - 7.7e-06 25.8 0.3 0.088 12.5 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_7 PF12775.7 CCD22386.1 - 1e-05 25.1 0.1 0.084 12.4 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 CCD22386.1 - 1.5e-05 24.7 0.1 0.2 11.3 0.0 3.6 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 CCD22386.1 - 2e-05 24.3 7.1 0.45 10.1 0.2 4.5 2 2 2 4 4 4 1 AAA domain Bac_DnaA PF00308.18 CCD22386.1 - 2.2e-05 24.4 0.0 0.055 13.3 0.0 3.0 3 0 0 3 3 2 1 Bacterial dnaA protein Parvo_NS1 PF01057.17 CCD22386.1 - 3.9e-05 22.9 0.1 0.15 11.1 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.16 CCD22386.1 - 4.8e-05 22.9 0.5 0.19 11.2 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_28 PF13521.6 CCD22386.1 - 5.2e-05 23.5 0.0 0.55 10.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 CCD22386.1 - 8.4e-05 23.0 0.1 0.56 10.6 0.0 3.3 3 1 0 3 3 2 2 AAA domain ABC_tran PF00005.27 CCD22386.1 - 8.9e-05 23.0 0.1 0.15 12.6 0.0 3.8 3 1 0 3 3 2 1 ABC transporter DUF815 PF05673.13 CCD22386.1 - 0.0001 21.6 0.0 0.11 11.6 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_3 PF07726.11 CCD22386.1 - 0.00017 21.5 0.0 0.79 9.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 CCD22386.1 - 0.00021 21.3 0.3 0.14 12.2 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 CCD22386.1 - 0.00026 20.9 1.5 0.96 9.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain TsaE PF02367.17 CCD22386.1 - 0.00029 20.8 0.0 0.53 10.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 CCD22386.1 - 0.00057 19.2 0.0 1 8.5 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CCD22386.1 - 0.00099 19.1 0.1 2.2 8.2 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 CCD22386.1 - 0.0015 18.3 0.4 2.3 7.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CCD22386.1 - 0.0023 18.3 0.4 2.9 8.2 0.0 3.1 2 1 1 3 3 2 1 AAA domain ATPase_2 PF01637.18 CCD22386.1 - 0.0031 17.4 2.4 2.8 7.8 0.1 4.1 3 2 1 4 4 3 1 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 CCD22386.1 - 0.013 15.6 0.0 1.5 8.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CCD22386.1 - 0.017 14.4 0.0 7.3 5.8 0.0 3.0 2 0 0 2 2 2 0 Zeta toxin IPT PF01745.16 CCD22386.1 - 0.017 14.5 0.1 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase eIF-1a PF01176.19 CCD22386.1 - 0.028 14.2 0.5 0.28 11.0 0.2 2.6 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 KAP_NTPase PF07693.14 CCD22386.1 - 0.028 13.7 0.2 2.1 7.5 0.0 2.8 2 2 1 3 3 3 0 KAP family P-loop domain NB-ARC PF00931.22 CCD22386.1 - 0.029 13.6 0.0 5.3 6.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 CCD22386.1 - 0.031 14.2 1.2 8.3 6.3 0.0 4.1 4 0 0 4 4 4 0 NTPase Zot PF05707.12 CCD22386.1 - 0.04 13.6 0.0 2.7 7.6 0.0 3.2 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Cytidylate_kin PF02224.18 CCD22386.1 - 0.055 13.2 0.0 7.9 6.2 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_6 PF12774.7 CCD22386.1 - 0.13 11.3 0.4 5.2 5.9 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region UFD1 PF03152.14 CCD22386.1 - 0.16 11.4 0.0 0.49 9.8 0.0 1.7 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Tankyrase_bdg_C PF15327.6 CCD22386.1 - 0.53 10.7 3.5 0.79 10.2 2.6 1.7 1 1 1 2 2 1 0 Tankyrase binding protein C terminal domain HIT PF01230.23 CCD22387.1 - 3.4e-25 88.6 0.1 4.3e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CCD22387.1 - 5.8e-08 33.2 0.6 8.2e-08 32.7 0.1 1.4 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CCD22387.1 - 0.022 14.6 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Aldo_ket_red PF00248.21 CCD22388.1 - 1.5e-41 142.6 0.0 2.3e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Pmp3 PF01679.17 CCD22389.1 - 5.9e-20 71.2 6.2 8.3e-20 70.7 6.2 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator zf-CCHC PF00098.23 CCD22390.1 - 8.1e-14 51.0 41.7 1.2e-05 25.2 3.4 4.8 4 1 0 4 4 4 3 Zinc knuckle zf-CCHC_2 PF13696.6 CCD22390.1 - 0.0013 18.5 45.5 0.017 14.9 3.9 5.3 5 0 0 5 5 5 4 Zinc knuckle zf-C2H2_10 PF16588.5 CCD22390.1 - 0.014 15.1 3.4 0.014 15.1 3.4 4.5 4 1 1 5 5 5 0 C2H2 zinc-finger Mpp10 PF04006.12 CCD22390.1 - 2.8 6.3 23.0 3.9 5.8 23.0 1.1 1 0 0 1 1 1 0 Mpp10 protein tRNA-synt_2b PF00587.25 CCD22391.1 - 7.4e-34 117.3 0.0 1.5e-33 116.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CCD22391.1 - 4.3e-21 74.9 0.9 1e-20 73.6 0.9 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 CCD22391.1 - 1.8e-15 56.7 0.0 4.8e-15 55.3 0.0 1.7 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 CCD22391.1 - 4.2e-13 49.2 0.0 8.5e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF1689 PF07954.11 CCD22392.1 - 2.7e-55 186.8 0.9 4.8e-55 186.0 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) NiFeSe_Hases PF00374.19 CCD22392.1 - 0.026 13.5 0.1 0.033 13.1 0.1 1.1 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Coatomer_E PF04733.14 CCD22393.1 - 1.3e-11 44.5 8.6 2.7e-11 43.4 8.6 1.5 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_1 PF00515.28 CCD22393.1 - 0.012 15.4 2.0 0.085 12.7 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CCD22393.1 - 0.26 11.5 1.4 7.4 6.9 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CCD22393.1 - 0.33 11.5 4.7 18 5.9 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.19 CCD22394.1 - 4.1e-54 182.6 0.0 1.1e-53 181.3 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CCD22394.1 - 5e-38 129.8 0.1 6.5e-38 129.4 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 CCD22394.1 - 2.4e-05 24.5 0.1 5.3e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 CCD22394.1 - 3.9e-05 23.9 0.4 0.00012 22.3 0.4 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 CCD22394.1 - 0.0046 17.5 0.1 0.019 15.5 0.1 2.0 2 0 0 2 2 2 1 XdhC Rossmann domain ACT PF01842.25 CCD22394.1 - 0.012 15.4 0.1 0.046 13.5 0.0 2.0 2 0 0 2 2 2 0 ACT domain IlvN PF07991.12 CCD22394.1 - 0.023 14.2 0.4 0.069 12.7 0.1 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 CCD22394.1 - 0.065 13.1 0.2 0.23 11.3 0.2 1.9 1 1 0 1 1 1 0 Rossmann-like domain SPO22 PF08631.10 CCD22395.1 - 1.7e-69 234.4 15.6 2.2e-68 230.7 6.2 2.9 3 0 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like DUF3452 PF11934.8 CCD22395.1 - 0.0075 15.8 0.2 0.043 13.4 0.2 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3452) TPR_8 PF13181.6 CCD22395.1 - 0.08 13.2 0.3 42 4.7 0.1 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4611 PF15387.6 CCD22396.1 - 0.077 13.2 4.1 0.2 11.9 4.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) HORMA PF02301.18 CCD22397.1 - 8.1e-59 198.7 1.0 1.6e-58 197.8 1.0 1.5 1 0 0 1 1 1 1 HORMA domain PHD_2 PF13831.6 CCD22397.1 - 0.13 11.8 5.0 0.35 10.5 5.0 1.7 1 0 0 1 1 1 0 PHD-finger PCI PF01399.27 CCD22398.1 - 0.0047 17.4 0.1 0.0047 17.4 0.1 2.7 2 1 1 3 3 3 1 PCI domain MAM33 PF02330.16 CCD22399.1 - 1.1e-61 208.5 8.6 1.3e-61 208.2 8.6 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF3567 PF12091.8 CCD22399.1 - 0.045 13.9 0.9 2.5 8.3 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3567) DUF1400 PF07176.11 CCD22399.1 - 0.15 12.4 1.7 0.71 10.2 0.4 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) Ribosomal_S24e PF01282.19 CCD22400.1 - 3.6e-35 119.7 0.1 6e-35 119.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e LCCL PF03815.19 CCD22401.1 - 7.6e-08 32.4 0.1 1.3e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 LCCL domain Ribonuc_red_lgC PF02867.15 CCD22402.1 - 1.1e-182 608.3 0.0 1.4e-182 607.9 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CCD22402.1 - 1.7e-23 82.4 0.0 4.3e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CCD22402.1 - 1.4e-17 64.0 0.0 4e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain Fis1_TPR_C PF14853.6 CCD22403.1 - 2.1e-24 85.3 0.4 4.3e-24 84.3 0.4 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CCD22403.1 - 6.1e-16 57.8 0.2 1.1e-15 57.0 0.2 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_19 PF14559.6 CCD22403.1 - 0.012 16.1 0.0 0.031 14.8 0.0 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat ETRAMP PF09716.10 CCD22403.1 - 0.02 14.9 0.1 0.025 14.6 0.1 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TPR_2 PF07719.17 CCD22403.1 - 0.14 12.3 0.1 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_31 PF13847.6 CCD22404.1 - 1.3e-26 93.2 0.3 3.7e-26 91.8 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCD22404.1 - 1.2e-09 38.8 0.0 2.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCD22404.1 - 7.8e-07 29.8 0.0 1.6e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCD22404.1 - 9e-07 29.5 0.0 2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CCD22404.1 - 1.4e-06 28.4 0.0 3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CCD22404.1 - 7.3e-06 25.6 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CCD22404.1 - 8.4e-06 25.7 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CCD22404.1 - 0.00085 19.3 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_20 PF12147.8 CCD22404.1 - 0.0041 16.3 0.0 0.011 15.0 0.0 1.5 1 1 1 2 2 2 1 Putative methyltransferase PCMT PF01135.19 CCD22404.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 CCD22404.1 - 0.037 13.6 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 CCD22404.1 - 0.048 13.0 0.0 0.11 11.8 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) GCD14 PF08704.10 CCD22404.1 - 0.095 12.4 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Ran_BP1 PF00638.18 CCD22405.1 - 9.1e-34 116.3 0.0 2.6e-33 114.9 0.0 1.8 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CCD22405.1 - 0.0041 17.0 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 WH1 domain RGI1 PF10843.8 CCD22406.1 - 1.9e-38 132.1 11.7 3.3e-38 131.3 11.7 1.3 1 1 0 1 1 1 1 Respiratory growth induced protein 1 Vhr1 PF04001.13 CCD22407.1 - 1.3e-42 144.0 2.9 1.3e-42 144.0 2.9 1.9 2 0 0 2 2 2 1 Transcription factor Vhr1 Glyco_transf_6 PF03414.13 CCD22407.1 - 0.073 11.8 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 6 PAT1 PF09770.9 CCD22408.1 - 0.042 12.1 13.2 0.059 11.6 13.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TPP_enzyme_N PF02776.18 CCD22409.1 - 2e-30 105.7 0.0 3.8e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCD22409.1 - 1.6e-26 92.6 0.0 4.6e-26 91.2 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCD22409.1 - 1.7e-14 53.9 0.0 3.2e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 CCD22409.1 - 0.0034 17.2 0.0 0.0093 15.7 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Tho1_MOS11_C PF18592.1 CCD22410.1 - 1.1e-26 92.4 3.0 2.8e-26 91.1 2.4 2.0 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain SAP PF02037.27 CCD22410.1 - 1.9e-10 40.3 2.5 2.4e-10 39.9 0.4 2.4 3 0 0 3 3 3 1 SAP domain HeH PF12949.7 CCD22410.1 - 0.096 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain HAD_2 PF13419.6 CCD22411.1 - 4.6e-14 52.9 0.0 6.4e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCD22411.1 - 2.5e-10 41.0 0.0 1.4e-08 35.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCD22411.1 - 0.0012 18.9 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Ribosomal_L34e PF01199.18 CCD22412.1 - 3.3e-42 142.7 4.7 3.3e-42 142.7 4.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L34e EndIII_4Fe-2S PF10576.9 CCD22412.1 - 0.35 11.3 2.1 0.41 11.0 0.1 2.1 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Ribonuc_L-PSP PF01042.21 CCD22413.1 - 1.4e-42 144.5 0.7 1.7e-42 144.3 0.7 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Cyclin PF08613.11 CCD22414.1 - 3.2e-49 167.4 1.8 3.2e-49 167.4 1.8 3.4 2 2 1 3 3 3 1 Cyclin Transp_cyt_pur PF02133.15 CCD22415.1 - 1e-92 311.2 42.5 1.2e-92 311.0 42.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CAAD PF14159.6 CCD22415.1 - 7.5 6.5 8.8 0.21 11.5 1.1 2.4 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Steroid_dh PF02544.16 CCD22416.1 - 5.2e-08 33.0 10.0 5.2e-08 33.0 10.0 2.3 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase RhoGAP PF00620.27 CCD22416.1 - 0.058 13.2 0.2 6.2 6.6 0.0 2.4 2 0 0 2 2 2 0 RhoGAP domain PhoLip_ATPase_C PF16212.5 CCD22417.1 - 1e-51 176.1 12.3 1e-51 176.1 12.3 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCD22417.1 - 6.1e-18 64.3 1.1 6.1e-18 64.3 1.1 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CCD22417.1 - 1.6e-12 47.3 0.0 4.6e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CCD22417.1 - 6.2e-12 46.3 0.3 6.2e-06 26.6 0.5 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCD22417.1 - 2.9e-10 40.1 0.0 2.1e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CCD22417.1 - 0.0031 17.3 0.5 0.022 14.5 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase EXS PF03124.14 CCD22418.1 - 5.1e-87 292.3 33.2 5.1e-87 292.3 33.2 1.6 2 0 0 2 2 2 1 EXS family SPX PF03105.19 CCD22418.1 - 7.5e-40 138.0 44.8 7.5e-40 138.0 44.8 2.6 2 1 0 2 2 2 1 SPX domain DUF2527 PF10736.9 CCD22418.1 - 1.7 8.6 4.2 4.1 7.3 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) WD40 PF00400.32 CCD22419.1 - 9e-36 121.3 26.6 1.1e-06 29.2 0.7 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 CCD22419.1 - 5.8e-12 45.3 1.7 1.1e-11 44.5 1.7 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 CCD22419.1 - 8.2e-12 44.5 7.4 0.0046 15.7 0.1 5.3 3 2 2 5 5 5 4 Nucleoporin Nup120/160 F-box PF00646.33 CCD22419.1 - 6.5e-08 32.3 2.8 1.5e-07 31.2 2.8 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 CCD22419.1 - 8.7e-07 29.2 0.6 4.2 7.7 0.0 5.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PAN_4 PF14295.6 CCD22419.1 - 0.043 13.7 1.1 0.13 12.2 1.1 1.8 1 0 0 1 1 1 0 PAN domain BPL_N PF09825.9 CCD22419.1 - 1.1 8.3 6.4 3.1 6.8 6.4 1.8 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal CBM_21 PF03370.13 CCD22420.1 - 6.1e-29 100.5 6.5 1.8e-28 99.0 6.5 1.8 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CCD22420.1 - 1.1e-08 35.5 7.0 3.4e-08 34.0 7.0 1.8 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) DNA_pol_phi PF04931.13 CCD22420.1 - 1.4 6.9 14.3 1.9 6.5 14.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi ArfGap PF01412.18 CCD22421.1 - 7.1e-36 122.8 0.3 7.1e-36 122.8 0.3 2.9 3 1 0 3 3 3 1 Putative GTPase activating protein for Arf TMEM174 PF15029.6 CCD22421.1 - 0.64 9.7 5.1 1.2 8.8 5.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 174 NAD_binding_1 PF00175.21 CCD22422.1 - 2.6e-30 105.3 0.0 5.6e-30 104.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CCD22422.1 - 1.1e-29 102.6 0.0 1.8e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CCD22422.1 - 3.3e-05 24.0 0.0 0.097 12.8 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CCD22422.1 - 0.043 14.0 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain BCDHK_Adom3 PF10436.9 CCD22423.1 - 3.9e-23 82.1 1.4 5.1e-23 81.7 0.4 1.7 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CCD22423.1 - 6.1e-13 49.3 0.1 4.3e-11 43.3 0.1 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 CCD22423.1 - 0.0067 16.4 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 CCD22423.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BAR_2 PF10455.9 CCD22424.1 - 5.3e-77 258.8 21.3 5.3e-77 258.8 21.3 1.6 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 CCD22424.1 - 1.4e-12 47.8 17.0 5.1e-11 42.7 15.0 2.7 1 1 1 2 2 2 1 BAR domain DUF3439 PF11921.8 CCD22424.1 - 0.0057 16.6 1.4 0.0057 16.6 1.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) Apq12 PF12716.7 CCD22425.1 - 0.15 12.1 10.7 0.25 11.3 8.9 2.2 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis WT1 PF02165.15 CCD22425.1 - 0.17 11.1 5.7 0.22 10.7 5.7 1.1 1 0 0 1 1 1 0 Wilm's tumour protein Not3 PF04065.15 CCD22427.1 - 7.1e-81 271.0 26.7 7.1e-81 271.0 26.7 2.7 2 1 1 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CCD22427.1 - 4.5e-21 75.3 1.0 1.8e-20 73.3 1.0 2.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 CCD22427.1 - 0.013 15.9 1.9 0.013 15.9 1.9 4.3 5 0 0 5 5 5 0 Syntaxin-like protein bZIP_1 PF00170.21 CCD22429.1 - 3.5e-14 52.7 9.0 1e-13 51.1 9.0 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CCD22429.1 - 3.2e-06 27.1 8.4 1.2e-05 25.2 8.4 2.0 1 0 0 1 1 1 1 Basic region leucine zipper Pkinase PF00069.25 CCD22430.1 - 1.3e-57 195.2 5.0 7.3e-51 173.0 0.5 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22430.1 - 1.2e-18 67.4 0.4 1.6e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CCD22430.1 - 2.4e-05 24.4 0.0 8e-05 22.7 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCD22430.1 - 0.0078 15.0 0.3 0.015 14.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CCD22430.1 - 0.026 13.9 0.4 0.076 12.4 0.4 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CCD22430.1 - 0.045 13.3 0.2 0.045 13.3 0.2 2.3 3 0 0 3 3 3 0 Choline/ethanolamine kinase DUF496 PF04363.12 CCD22430.1 - 0.3 11.1 2.7 1.6 8.8 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF496) cNMP_binding PF00027.29 CCD22431.1 - 2.9e-43 145.8 0.1 4.3e-22 78.0 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PfkB PF00294.24 CCD22431.1 - 0.023 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Cupin_2 PF07883.11 CCD22431.1 - 0.066 12.9 3.7 1.6 8.5 0.1 2.7 3 0 0 3 3 3 0 Cupin domain Ribosomal_L27 PF01016.19 CCD22431.1 - 0.15 12.1 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomal L27 protein AMPK1_CBM PF16561.5 CCD22432.1 - 0.00058 20.0 1.2 0.0023 18.1 1.2 2.0 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 CCD22432.1 - 0.0032 18.0 0.4 0.01 16.4 0.4 1.8 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Zip PF02535.22 CCD22433.1 - 1.7e-52 178.7 14.9 1.7e-52 178.7 14.9 2.1 2 1 0 2 2 2 1 ZIP Zinc transporter DUF4834 PF16118.5 CCD22433.1 - 0.00037 21.4 0.3 0.0031 18.4 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) MMgT PF10270.9 CCD22434.1 - 4e-23 81.6 0.1 5.4e-23 81.2 0.1 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter RINGv PF12906.7 CCD22435.1 - 1.3e-15 57.2 5.5 2.4e-15 56.4 5.5 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 CCD22435.1 - 0.93 9.9 6.3 3.2 8.2 6.5 1.8 1 1 1 2 2 2 0 Ring finger domain Peptidase_C48 PF02902.19 CCD22436.1 - 1.2e-37 129.9 2.6 1.2e-37 129.9 2.6 1.8 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain EF-hand_4 PF12763.7 CCD22437.1 - 3.6e-22 78.3 0.0 3.2e-10 39.9 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CCD22437.1 - 1.9e-06 28.2 0.0 0.0053 17.2 0.2 3.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CCD22437.1 - 5.9e-06 25.5 0.0 0.15 11.7 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CCD22437.1 - 1e-05 25.0 0.0 3.8 7.7 0.0 4.3 4 0 0 4 4 4 2 EF-hand domain DUF1720 PF08226.11 CCD22437.1 - 3.5e-05 24.1 61.1 0.00043 20.6 21.3 8.8 2 2 4 7 7 7 5 Domain of unknown function (DUF1720) Cwf_Cwc_15 PF04889.12 CCD22437.1 - 0.0017 18.2 6.9 0.0017 18.2 6.9 3.1 3 1 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein DUF2701 PF10857.8 CCD22437.1 - 0.062 13.3 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) DUF826 PF05696.11 CCD22437.1 - 0.13 12.4 0.1 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF826) FAM150 PF15129.6 CCD22437.1 - 4 7.6 11.1 0.29 11.3 0.1 3.7 3 0 0 3 3 3 0 FAM150 family RRM_1 PF00076.22 CCD22438.1 - 1.2e-20 73.1 0.0 2.4e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD22438.1 - 4.9e-06 26.6 0.1 1.4e-05 25.1 0.0 1.8 2 1 0 2 2 2 1 RNA recognition motif DnaJ-X PF14308.6 CCD22439.1 - 1.5e-76 256.5 3.9 1.5e-76 256.5 3.9 2.5 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CCD22439.1 - 6.6e-25 87.0 1.0 2.2e-24 85.4 1.0 2.0 1 0 0 1 1 1 1 DnaJ domain Zip PF02535.22 CCD22439.1 - 0.025 13.8 1.9 0.038 13.2 1.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 CCD22439.1 - 0.3 9.9 12.9 1.9 7.2 0.1 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain ANTH PF07651.16 CCD22440.1 - 7.4e-59 199.0 0.7 7.4e-59 199.0 0.7 2.6 3 0 0 3 3 3 1 ANTH domain ENTH PF01417.20 CCD22440.1 - 2.4e-06 27.6 4.2 2.8e-06 27.4 0.3 2.6 2 1 0 2 2 2 1 ENTH domain TBPIP PF07106.13 CCD22440.1 - 0.045 13.7 1.8 2.8 7.9 0.1 2.9 3 0 0 3 3 3 0 TBPIP/Hop2 winged helix domain ATP-sulfurylase PF01747.17 CCD22440.1 - 0.12 11.8 1.4 0.22 11.0 1.4 1.4 1 0 0 1 1 1 0 ATP-sulfurylase D123 PF07065.14 CCD22441.1 - 1.6e-115 385.5 5.3 2.5e-115 384.8 5.3 1.3 1 0 0 1 1 1 1 D123 CDP-OH_P_transf PF01066.21 CCD22442.1 - 1.7e-16 60.8 2.9 4.2e-16 59.5 2.9 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Pro_isomerase PF00160.21 CCD22443.1 - 6.2e-46 156.5 0.4 1.1e-45 155.8 0.1 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 CCD22443.1 - 5.2e-05 22.9 1.2 0.00029 20.5 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CCD22443.1 - 5.2e-05 23.0 0.7 0.0025 17.8 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCD22443.1 - 0.005 17.0 2.5 0.014 15.5 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CCD22443.1 - 0.0097 16.0 0.5 0.017 15.3 0.5 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TFIID_NTD2 PF04494.15 CCD22443.1 - 0.034 14.4 0.1 0.069 13.4 0.1 1.5 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain TPR_6 PF13174.6 CCD22443.1 - 0.046 14.4 0.2 0.046 14.4 0.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Glu_cys_ligase PF04262.14 CCD22443.1 - 0.048 12.3 0.6 0.095 11.3 0.0 1.7 2 0 0 2 2 2 0 Glutamate-cysteine ligase CHCH PF06747.13 CCD22444.1 - 1.9e-06 27.8 8.1 3e-06 27.2 8.1 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 CCD22444.1 - 0.049 13.7 2.4 0.052 13.6 0.5 1.9 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Sec31 PF11549.8 CCD22445.1 - 3e-25 87.8 2.9 1.4e-24 85.8 2.9 2.2 1 0 0 1 1 1 1 Protein transport protein SEC31 ANAPC4_WD40 PF12894.7 CCD22445.1 - 1.9e-08 34.5 0.2 0.47 10.8 0.0 3.8 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCD22445.1 - 8.7e-07 29.5 7.6 2.3 9.2 0.0 6.5 6 0 0 6 6 6 1 WD domain, G-beta repeat Sec16_C PF12931.7 CCD22445.1 - 2.5e-06 27.4 2.5 7.2e-06 25.9 2.5 1.7 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 CCD22445.1 - 4.5e-05 23.3 2.6 5.5e-05 23.0 0.1 2.6 2 1 0 2 2 2 1 Steroid receptor RNA activator (SRA1) eIF2A PF08662.11 CCD22445.1 - 8e-05 22.6 0.5 0.0011 19.0 0.1 2.5 1 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Prp18 PF02840.15 CCD22445.1 - 0.011 15.8 2.0 0.023 14.8 0.4 2.3 2 1 0 2 2 2 0 Prp18 domain Serglycin PF04360.12 CCD22445.1 - 0.029 14.3 0.3 2 8.3 0.1 2.5 2 0 0 2 2 2 0 Serglycin Sugar_tr PF00083.24 CCD22446.1 - 2.1e-129 432.3 29.1 2.5e-129 432.1 29.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD22446.1 - 2.3e-21 76.1 34.7 6.4e-15 54.9 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Arf PF00025.21 CCD22448.1 - 3.4e-78 261.1 0.0 3.9e-78 260.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCD22448.1 - 1.4e-14 54.3 0.1 1.9e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CCD22448.1 - 3e-14 52.9 0.0 3.2e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CCD22448.1 - 7.3e-14 51.6 0.0 8.9e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CCD22448.1 - 5.3e-12 45.6 1.0 3.8e-08 32.9 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CCD22448.1 - 1.4e-09 37.7 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCD22448.1 - 1.9e-05 24.7 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 CCD22448.1 - 0.0081 15.8 0.2 0.015 14.9 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ABC_tran PF00005.27 CCD22448.1 - 0.038 14.5 0.1 0.07 13.7 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 CCD22448.1 - 0.041 14.0 0.6 0.1 12.8 0.6 1.9 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 CCD22448.1 - 0.047 13.0 0.2 0.072 12.4 0.2 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.19 CCD22448.1 - 0.053 13.1 0.1 7.5 6.1 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 CCD22448.1 - 0.055 13.0 0.0 0.17 11.4 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCD22448.1 - 0.069 13.1 0.1 9.7 6.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 CCD22448.1 - 0.089 13.3 0.1 0.14 12.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CCD22448.1 - 0.15 12.0 0.4 14 5.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Thymidylate_kin PF02223.17 CCD22448.1 - 0.24 11.1 0.5 0.97 9.1 0.3 1.8 2 0 0 2 2 2 0 Thymidylate kinase Vps5 PF09325.10 CCD22449.1 - 3.8e-40 137.9 15.2 5.6e-40 137.3 15.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 CCD22449.1 - 2.1e-10 40.6 0.1 6.8e-10 38.9 0.1 1.9 1 0 0 1 1 1 1 PX domain ELF PF03317.13 CCD22449.1 - 0.003 17.5 0.9 0.0097 15.9 0.2 2.1 2 0 0 2 2 2 1 ELF protein Mod_r PF07200.13 CCD22449.1 - 9.8 6.3 17.0 0.07 13.2 6.4 2.7 2 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Ufd2P_core PF10408.9 CCD22450.1 - 6.3e-203 675.9 12.5 6.3e-203 675.9 12.5 1.7 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.15 CCD22450.1 - 2.5e-27 94.9 1.0 2.5e-27 94.9 1.0 2.3 3 0 0 3 3 3 1 U-box domain Peptidase_M32 PF02074.15 CCD22450.1 - 0.042 12.6 0.4 0.093 11.5 0.4 1.5 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase R3H PF01424.22 CCD22451.1 - 2.7e-09 36.9 0.1 5.6e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 R3H domain Metallophos PF00149.28 CCD22452.1 - 9.8e-33 114.4 0.4 1.5e-32 113.8 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3425 PF11905.8 CCD22453.1 - 0.041 13.9 0.3 0.088 12.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3425) Ribosomal_L41 PF05162.13 CCD22454.1 - 1.2e-10 41.2 26.3 1.3e-10 41.2 26.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 Mit_KHE1 PF10173.9 CCD22455.1 - 1.3e-54 185.1 1.0 1.8e-54 184.7 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related HMGL-like PF00682.19 CCD22456.1 - 5.1e-85 285.2 0.1 7.9e-85 284.6 0.1 1.3 1 0 0 1 1 1 1 HMGL-like SidE PF12252.8 CCD22456.1 - 0.0075 13.9 0.1 0.01 13.4 0.1 1.1 1 0 0 1 1 1 1 Dot/Icm substrate protein FliG_N PF14842.6 CCD22456.1 - 0.17 12.5 0.0 0.33 11.5 0.0 1.4 1 0 0 1 1 1 0 FliG N-terminal domain Ribosomal_60s PF00428.19 CCD22457.1 - 1e-23 83.7 13.4 1.2e-23 83.5 13.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sigma70_ner PF04546.13 CCD22457.1 - 0.11 12.4 0.5 0.13 12.2 0.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Na_Ca_ex PF01699.24 CCD22459.1 - 1.4e-48 164.7 35.3 9.3e-26 90.6 8.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YWFCY PF14293.6 CCD22459.1 - 0.012 15.9 0.0 0.12 12.7 0.0 2.8 2 0 0 2 2 2 0 YWFCY protein Phage_holin_4_1 PF05105.12 CCD22459.1 - 0.1 12.8 9.3 2 8.6 7.1 3.2 1 1 0 2 2 2 0 Bacteriophage holin family Cyclin_N PF00134.23 CCD22460.1 - 6.7e-11 42.0 0.2 1.2e-10 41.2 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pec_lyase_N PF04431.13 CCD22460.1 - 0.45 10.8 8.4 2.8 8.3 0.2 2.6 2 0 0 2 2 2 0 Pectate lyase, N terminus AAA PF00004.29 CCD22461.1 - 2.6e-98 325.5 0.0 4e-48 163.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCD22461.1 - 2.9e-23 81.4 4.6 1.2e-11 44.2 0.4 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 CCD22461.1 - 5.3e-17 61.8 0.1 1.7e-16 60.2 0.1 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CCD22461.1 - 9.4e-14 51.5 0.0 1.6e-05 24.7 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CCD22461.1 - 1.7e-13 51.1 0.2 4.8e-07 30.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CCD22461.1 - 4.2e-13 50.0 0.2 0.00014 22.3 0.0 4.8 3 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 CCD22461.1 - 9.6e-12 45.1 0.4 8.3e-06 25.8 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CCD22461.1 - 4.4e-11 43.1 0.0 2.1e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CCD22461.1 - 3.1e-09 36.5 0.0 0.0016 17.7 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 CCD22461.1 - 2.7e-08 34.2 2.6 0.072 13.4 0.1 4.4 3 2 1 4 4 3 2 AAA domain CDC48_2 PF02933.17 CCD22461.1 - 1.3e-07 31.3 0.1 3.1e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Vps4_C PF09336.10 CCD22461.1 - 2.4e-07 30.7 0.8 3.1e-05 23.9 0.1 3.0 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 CCD22461.1 - 3.1e-07 30.7 0.0 0.012 16.0 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 CCD22461.1 - 3.3e-07 29.9 0.3 0.026 13.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CCD22461.1 - 5.4e-07 29.7 0.0 0.025 14.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CCD22461.1 - 1e-06 28.6 0.0 0.032 14.0 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase PF06745.13 CCD22461.1 - 1.4e-06 27.9 1.3 0.28 10.5 0.0 3.6 2 1 0 3 3 3 2 KaiC AAA_24 PF13479.6 CCD22461.1 - 4.4e-06 26.5 0.1 0.09 12.5 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.6 CCD22461.1 - 7.5e-06 26.5 0.0 0.24 12.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 CCD22461.1 - 8.7e-06 25.7 0.0 0.046 13.6 0.0 3.2 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_7 PF12775.7 CCD22461.1 - 1e-05 25.2 0.1 0.086 12.3 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 CCD22461.1 - 1.2e-05 25.9 0.3 0.11 13.0 0.0 4.3 3 1 0 3 3 3 1 ABC transporter AAA_25 PF13481.6 CCD22461.1 - 1.3e-05 24.9 4.6 0.062 12.9 0.3 4.0 2 2 1 3 3 3 1 AAA domain Sigma54_activat PF00158.26 CCD22461.1 - 1.5e-05 24.8 0.1 0.18 11.5 0.0 3.5 3 1 0 3 3 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.17 CCD22461.1 - 3.7e-05 23.0 0.1 0.15 11.1 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.16 CCD22461.1 - 5e-05 22.8 0.5 0.19 11.1 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_28 PF13521.6 CCD22461.1 - 5e-05 23.6 0.0 0.57 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 CCD22461.1 - 8.4e-05 21.9 0.0 0.097 11.8 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_3 PF07726.11 CCD22461.1 - 0.00016 21.6 0.0 0.75 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 CCD22461.1 - 0.00021 21.4 1.4 0.14 12.1 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit TsaE PF02367.17 CCD22461.1 - 0.00032 20.7 0.0 0.54 10.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 CCD22461.1 - 0.00055 20.4 3.5 0.57 10.6 0.0 3.8 5 0 0 5 5 2 2 AAA domain DUF2075 PF09848.9 CCD22461.1 - 0.00058 19.2 0.0 1.1 8.5 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CCD22461.1 - 0.00099 19.1 0.1 2.3 8.1 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 CCD22461.1 - 0.0012 18.6 0.3 2.3 7.9 0.1 2.7 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CCD22461.1 - 0.0029 17.6 1.3 2.6 7.9 0.0 3.9 3 1 0 3 3 2 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 CCD22461.1 - 0.0031 17.4 8.0 0.98 9.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CCD22461.1 - 0.0032 17.8 1.2 2.6 8.4 0.0 3.3 2 2 1 3 3 2 1 AAA domain Sigma54_activ_2 PF14532.6 CCD22461.1 - 0.013 15.6 0.0 1.7 8.8 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain IPT PF01745.16 CCD22461.1 - 0.018 14.4 0.1 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zeta_toxin PF06414.12 CCD22461.1 - 0.019 14.3 0.6 7.5 5.8 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin NB-ARC PF00931.22 CCD22461.1 - 0.03 13.5 0.0 5.4 6.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 CCD22461.1 - 0.033 14.1 1.7 8.3 6.3 0.0 4.3 4 1 1 5 5 4 0 NTPase KAP_NTPase PF07693.14 CCD22461.1 - 0.038 13.2 0.2 2.2 7.4 0.0 2.9 2 2 0 2 2 2 0 KAP family P-loop domain Zot PF05707.12 CCD22461.1 - 0.045 13.4 0.0 2.7 7.6 0.0 3.1 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Cytidylate_kin PF02224.18 CCD22461.1 - 0.047 13.4 0.0 8 6.1 0.0 2.9 2 0 0 2 2 2 0 Cytidylate kinase UFD1 PF03152.14 CCD22461.1 - 0.054 13.0 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 AAA_6 PF12774.7 CCD22461.1 - 0.11 11.5 0.4 5.3 5.9 0.0 2.6 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region Viral_helicase1 PF01443.18 CCD22461.1 - 0.12 12.1 0.0 19 4.9 0.0 3.4 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase PTS_IIB PF02302.17 CCD22461.1 - 1.7 9.4 4.3 21 5.9 2.9 2.8 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit HIT PF01230.23 CCD22462.1 - 3.5e-19 69.4 0.1 5.9e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CCD22462.1 - 8.6e-07 29.4 0.2 1.7e-06 28.5 0.2 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CCD22462.1 - 0.062 13.2 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 FAD-oxidase_C PF02913.19 CCD22463.1 - 6.5e-45 153.7 0.0 9.2e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CCD22463.1 - 5.3e-31 107.2 0.0 8.3e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DnaGprimase_HBD PF16730.5 CCD22463.1 - 0.048 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 DnaG-primase C-terminal, helicase-binding domain TfoX_N PF04993.13 CCD22463.1 - 0.093 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 TfoX N-terminal domain zf-CCHC PF00098.23 CCD22464.1 - 0.00047 20.1 4.9 0.00086 19.3 4.9 1.5 1 0 0 1 1 1 1 Zinc knuckle DNase-RNase PF02577.14 CCD22464.1 - 0.026 14.2 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Bifunctional nuclease zf-CCHC_4 PF14392.6 CCD22464.1 - 0.049 13.4 1.8 0.11 12.2 1.8 1.6 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_L35p PF01632.19 CCD22464.1 - 0.2 12.2 6.1 5.9 7.5 2.6 2.7 2 0 0 2 2 2 0 Ribosomal protein L35 GET2 PF08690.10 CCD22465.1 - 2.4e-90 303.4 4.3 4.4e-90 302.5 4.3 1.4 1 1 0 1 1 1 1 GET complex subunit GET2 BING4CT PF08149.11 CCD22466.1 - 7.4e-39 131.4 0.0 2.2e-36 123.5 0.0 3.6 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 CCD22466.1 - 2.9e-05 24.7 0.1 0.063 14.2 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD22466.1 - 6.6e-05 23.1 0.0 4.7 7.6 0.0 4.7 2 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain YfkD PF14167.6 CCD22466.1 - 0.059 12.5 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 YfkD-like protein RPN2_C PF18004.1 CCD22467.1 - 2.2e-52 177.2 11.2 3.4e-52 176.6 11.2 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 CCD22467.1 - 6.6e-26 89.4 29.1 5.3e-05 23.5 0.0 9.1 11 0 0 11 11 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CCD22467.1 - 4.9e-16 58.9 0.8 2.8e-13 50.1 0.0 4.1 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 CCD22467.1 - 5.6e-06 26.7 1.5 0.34 11.5 0.1 4.3 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 CCD22467.1 - 2.5e-05 24.1 0.9 3.2 8.3 0.0 4.4 4 0 0 4 4 3 2 HEAT repeat DUF3824 PF12868.7 CCD22467.1 - 0.00083 20.0 3.7 0.0017 19.1 3.7 1.4 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) DUF669 PF05037.13 CCD22467.1 - 0.0055 16.8 0.1 0.014 15.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF669) Myc_N PF01056.18 CCD22467.1 - 0.02 14.8 4.1 0.032 14.1 4.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF4775 PF16001.5 CCD22467.1 - 0.044 13.2 13.5 0.063 12.7 13.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Med19 PF10278.9 CCD22467.1 - 0.08 12.9 9.4 0.11 12.4 8.4 1.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Cnd1 PF12717.7 CCD22467.1 - 0.12 12.4 1.9 9 6.3 0.0 3.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 CCD22467.1 - 0.14 12.4 1.1 1.2 9.4 0.0 3.2 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 RXT2_N PF08595.11 CCD22467.1 - 0.42 10.6 7.4 0.84 9.6 7.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP_sp32 PF07222.12 CCD22467.1 - 0.71 9.3 5.3 1.2 8.6 5.3 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 FAM176 PF14851.6 CCD22467.1 - 1.2 8.8 5.3 2.2 7.9 5.3 1.3 1 0 0 1 1 1 0 FAM176 family Vfa1 PF08432.10 CCD22467.1 - 2.2 8.6 15.3 3.7 7.8 15.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_Rpc4 PF05132.14 CCD22467.1 - 2.8 8.4 6.3 4.9 7.6 6.3 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 2-Hacid_dh_C PF02826.19 CCD22468.1 - 5.8e-54 182.1 0.0 9.7e-54 181.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CCD22468.1 - 1.5e-38 131.5 0.1 2e-38 131.1 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CCD22468.1 - 5.3e-06 26.7 1.4 8.5e-06 26.0 0.3 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 CCD22468.1 - 4.8e-05 23.5 0.0 9.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 CCD22468.1 - 0.0062 17.0 0.1 0.018 15.6 0.1 1.8 2 0 0 2 2 2 1 XdhC Rossmann domain ACT PF01842.25 CCD22468.1 - 0.0089 15.8 0.1 0.068 13.0 0.0 2.5 2 1 0 2 2 2 1 ACT domain IlvN PF07991.12 CCD22468.1 - 0.012 15.2 0.1 0.025 14.1 0.1 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain APH PF01636.23 CCD22469.1 - 2.3e-07 31.0 0.0 1.1e-06 28.8 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CCD22469.1 - 0.00034 20.0 0.0 0.57 9.5 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Sulfatase_C PF14707.6 CCD22469.1 - 0.01 16.5 0.3 0.045 14.5 0.0 2.1 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase HMG_box PF00505.19 CCD22469.1 - 3.1 8.3 6.1 1.7 9.1 2.5 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box Peptidase_M24 PF00557.24 CCD22470.1 - 1.1e-52 178.7 0.0 1.7e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CCD22470.1 - 7.2e-37 125.9 0.0 1.3e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain ALIX_LYPXL_bnd PF13949.6 CCD22470.1 - 0.035 13.4 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV PPR_2 PF13041.6 CCD22471.1 - 3.8e-15 55.8 0.4 5e-11 42.6 0.0 3.0 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 CCD22471.1 - 0.067 13.3 0.0 0.32 11.1 0.0 2.2 1 0 0 1 1 1 0 Pentatricopeptide repeat domain Y_phosphatase PF00102.27 CCD22472.1 - 6.4e-46 156.8 0.1 1.1e-45 156.1 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 CCD22472.1 - 1.2e-08 35.5 0.0 7.3e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain dUTPase_2 PF08761.11 CCD22472.1 - 0.0014 18.8 0.8 0.93 9.6 0.0 3.4 3 0 0 3 3 3 2 dUTPase DSPc PF00782.20 CCD22472.1 - 0.019 14.8 0.0 0.1 12.4 0.0 2.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CCD22472.1 - 0.051 13.5 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family Yos1 PF08571.10 CCD22473.1 - 1.3e-31 108.6 1.0 1.5e-31 108.5 1.0 1.0 1 0 0 1 1 1 1 Yos1-like Lactamase_B_4 PF13691.6 CCD22474.1 - 8.6e-26 89.4 0.0 2e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 CCD22474.1 - 6e-10 39.0 0.0 0.00055 19.5 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain DASH_Dad2 PF08654.10 CCD22475.1 - 3.5e-28 97.9 0.5 3.5e-28 97.9 0.5 1.6 2 0 0 2 2 2 1 DASH complex subunit Dad2 NuiA PF07924.11 CCD22475.1 - 0.022 15.1 0.9 0.17 12.3 0.1 2.1 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein MRP-L20 PF12824.7 CCD22477.1 - 8.5e-43 146.3 1.9 1.1e-42 146.0 1.9 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 THF_DHG_CYH PF00763.23 CCD22478.1 - 7.4e-25 87.5 0.1 1.3e-24 86.7 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 CCD22478.1 - 1e-15 57.4 0.0 4.8e-10 39.0 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FTP PF07504.13 CCD22478.1 - 0.028 14.2 1.6 0.06 13.2 1.6 1.5 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif LIAS_N PF16881.5 CCD22478.1 - 0.031 14.7 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family Syntaxin-18_N PF10496.9 CCD22479.1 - 4.2e-16 59.0 0.9 4.2e-16 59.0 0.9 2.3 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 CCD22479.1 - 1.9e-06 27.7 0.5 5.3e-06 26.3 0.3 1.9 2 0 0 2 2 2 1 SNARE domain SecG PF03840.14 CCD22479.1 - 0.013 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Spore_III_AB PF09548.10 CCD22479.1 - 0.43 10.7 5.0 0.55 10.3 0.0 2.8 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) GTP_EFTU PF00009.27 CCD22480.1 - 6.5e-44 149.8 0.6 1.3e-43 148.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 CCD22480.1 - 7.4e-14 51.8 5.1 7.4e-14 51.8 5.1 2.0 2 0 0 2 2 2 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 CCD22480.1 - 1.3e-08 35.1 0.2 1e-07 32.2 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CCD22480.1 - 1.7e-06 28.1 1.4 2.1e-05 24.6 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CCD22480.1 - 0.00062 20.1 0.1 0.0018 18.6 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 JHD PF17811.1 CCD22480.1 - 0.019 15.5 0.5 2.6 8.6 0.0 2.6 2 0 0 2 2 2 0 Jumonji helical domain Roc PF08477.13 CCD22480.1 - 0.031 14.5 3.8 0.66 10.2 0.0 2.7 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CCD22480.1 - 0.045 13.8 2.4 8.5 6.4 0.0 3.3 2 1 1 3 3 3 0 Dynamin family FeoB_N PF02421.18 CCD22480.1 - 0.19 11.3 2.1 1.9 8.0 0.2 3.3 3 2 0 3 3 3 0 Ferrous iron transport protein B TFIIA PF03153.13 CCD22481.1 - 1.1 9.2 21.3 3.8 7.4 21.3 1.8 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aldedh PF00171.22 CCD22482.1 - 2.3e-171 570.4 0.0 2.6e-171 570.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GST_N_2 PF13409.6 CCD22483.1 - 7.4e-23 80.6 0.0 5.6e-22 77.8 0.0 2.4 3 1 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CCD22483.1 - 3.9e-11 42.8 0.0 7.6e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CCD22483.1 - 0.0011 19.2 0.1 0.0036 17.5 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CCD22483.1 - 0.0089 16.4 0.0 5.7 7.4 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Formyl_trans_N PF00551.19 CCD22484.1 - 3.3e-23 82.3 0.0 4.9e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Acyltransferase PF01553.21 CCD22485.1 - 7.3e-10 38.6 0.0 3.1e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase YesK PF14150.6 CCD22485.1 - 0.68 10.2 6.4 0.37 11.0 1.9 2.5 1 1 1 2 2 2 0 YesK-like protein DUF5102 PF17104.5 CCD22486.1 - 3.8e-09 37.0 9.3 1e-08 35.6 9.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5102) DUF719 PF05334.13 CCD22486.1 - 0.15 12.3 6.7 10 6.3 0.9 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF719) ZapB PF06005.12 CCD22486.1 - 4.3 7.8 10.7 4.3 7.8 2.8 3.0 2 1 0 2 2 2 0 Cell division protein ZapB Haspin_kinase PF12330.8 CCD22487.1 - 9e-142 472.4 17.7 9e-142 472.4 17.7 4.4 3 2 0 4 4 4 1 Haspin like kinase domain WD40 PF00400.32 CCD22488.1 - 3.3e-32 110.0 17.4 1.7e-08 35.0 0.1 8.1 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD22488.1 - 8.6e-15 54.8 0.2 0.027 14.8 0.0 6.0 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CCD22488.1 - 1.9e-07 30.8 1.7 4.8 7.2 0.0 5.8 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat HIRA_B PF09453.10 CCD22488.1 - 2.1e-07 30.6 1.9 2.1e-07 30.6 1.9 2.2 2 0 0 2 2 2 1 HIRA B motif Hira PF07569.11 CCD22488.1 - 5.9e-06 26.2 0.0 3.4e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 TUP1-like enhancer of split eIF2A PF08662.11 CCD22488.1 - 1.4e-05 25.1 0.8 0.62 9.9 0.1 4.4 3 1 3 6 6 6 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CCD22488.1 - 1.6e-05 24.4 0.0 0.018 14.4 0.0 3.0 3 0 0 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 CCD22488.1 - 0.0003 19.8 0.0 0.36 9.7 0.0 3.8 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CCD22488.1 - 0.091 12.1 0.8 0.53 9.6 0.0 2.7 5 0 0 5 5 5 0 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.21 CCD22488.1 - 0.49 9.1 3.2 11 4.6 0.2 3.2 2 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Aconitase PF00330.20 CCD22489.1 - 3.3e-157 524.2 0.0 4e-157 523.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCD22489.1 - 1.4e-43 148.3 0.0 2.6e-43 147.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain SH3_1 PF00018.28 CCD22490.1 - 1.4e-35 120.7 5.0 5.5e-12 45.1 0.1 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 CCD22490.1 - 1.7e-32 111.1 7.2 3.5e-12 46.0 0.3 4.3 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.12 CCD22490.1 - 3.9e-32 109.9 0.0 7.7e-32 108.9 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 CCD22490.1 - 5.8e-30 102.7 0.1 2.1e-08 33.7 0.0 4.6 4 0 0 4 4 4 4 Variant SH3 domain SAM_4 PF18017.1 CCD22490.1 - 0.00015 21.7 0.0 0.00044 20.2 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CCD22490.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Rsc14 PF08586.10 CCD22491.1 - 1.2e-35 122.3 1.1 1.6e-35 121.8 0.4 1.6 2 0 0 2 2 2 1 RSC complex, Rsc14/Ldb7 subunit NTR2 PF15458.6 CCD22491.1 - 0.018 14.6 0.1 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Nineteen complex-related protein 2 ERG4_ERG24 PF01222.17 CCD22493.1 - 5.3e-181 602.1 30.9 6e-181 601.9 30.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family CytoC_RC PF02276.18 CCD22493.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit HEAT_EZ PF13513.6 CCD22494.1 - 5.7e-15 55.4 11.9 6.1e-11 42.6 0.0 7.4 7 1 1 8 8 7 1 HEAT-like repeat HEAT PF02985.22 CCD22494.1 - 4.7e-12 45.1 19.2 0.0011 19.1 0.1 9.1 10 0 0 10 10 9 3 HEAT repeat IBN_N PF03810.19 CCD22494.1 - 1.4e-11 44.1 7.4 1.8e-11 43.8 1.9 3.8 3 1 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.8 CCD22494.1 - 1.5e-05 24.7 1.4 2.5 7.6 0.0 5.2 4 2 3 7 7 7 2 CLASP N terminal HEAT_2 PF13646.6 CCD22494.1 - 1.5e-05 25.3 7.8 0.023 15.1 0.0 5.8 4 2 2 6 6 6 3 HEAT repeats Arm PF00514.23 CCD22494.1 - 0.00041 20.3 8.6 0.021 14.8 0.1 5.4 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 CCD22494.1 - 0.0021 18.1 7.8 0.059 13.4 0.0 4.8 4 3 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Sec7_N PF12783.7 CCD22494.1 - 0.083 12.8 0.5 1.6 8.6 0.0 3.3 3 2 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal AI-2E_transport PF01594.16 CCD22494.1 - 0.13 11.4 1.3 5.8 6.0 0.7 2.5 2 0 0 2 2 2 0 AI-2E family transporter DUF3347 PF11827.8 CCD22494.1 - 0.16 12.2 1.3 0.37 10.9 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) TIP120 PF08623.10 CCD22494.1 - 0.29 10.9 9.2 0.26 11.0 0.4 3.8 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) Telomere_reg-2 PF10193.9 CCD22494.1 - 0.46 11.0 3.7 4.8 7.7 0.0 4.4 3 2 1 5 5 5 0 Telomere length regulation protein Con-6 PF10346.9 CCD22494.1 - 9.7 6.3 5.7 4.9 7.3 0.6 2.7 3 0 0 3 3 3 0 Conidiation protein 6 Mito_carr PF00153.27 CCD22495.1 - 3.2e-54 180.8 0.8 2.1e-18 66.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_4 PF12799.7 CCD22496.1 - 0.003 17.9 26.3 0.31 11.5 2.1 6.1 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CCD22496.1 - 0.17 12.1 13.7 22 5.4 0.3 6.0 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 CCD22496.1 - 7.4 7.6 25.6 40 5.3 0.1 8.2 8 0 0 8 8 8 0 Leucine Rich Repeat MMADHC PF10229.9 CCD22497.1 - 0.057 13.2 1.7 0.1 12.3 0.2 2.2 2 0 0 2 2 2 0 Methylmalonic aciduria and homocystinuria type D protein Fungal_trans PF04082.18 CCD22498.1 - 4.2e-22 78.4 1.7 1.2e-21 77.0 1.7 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD22498.1 - 3.8e-09 36.5 13.9 7e-09 35.7 13.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 CCD22498.1 - 2.4 8.6 9.2 6.1 7.3 9.2 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Fungal_trans PF04082.18 CCD22499.1 - 2.1e-33 115.5 3.8 5e-33 114.3 3.8 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD22499.1 - 8.5e-09 35.4 12.5 1.7e-08 34.4 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 6PF2K PF01591.18 CCD22500.1 - 3.2e-57 193.4 6.3 4.5e-57 192.9 6.3 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CCD22500.1 - 7e-17 61.8 0.0 1.1e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_24 PF13479.6 CCD22500.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CCD22501.1 - 4.8e-34 117.8 0.1 9.3e-17 61.8 0.0 2.8 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 CCD22501.1 - 6e-15 54.8 4.4 1.5e-14 53.5 4.4 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 CCD22501.1 - 1.5e-10 41.4 7.4 0.024 14.4 0.1 4.2 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CCD22501.1 - 1.1e-07 32.5 0.0 0.00036 21.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Fer4 PF00037.27 CCD22501.1 - 2.8e-07 30.1 3.8 2.8e-07 30.1 3.8 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain SMC_N PF02463.19 CCD22501.1 - 5.1e-07 29.3 2.3 0.16 11.4 0.0 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CCD22501.1 - 2.2e-06 28.0 0.0 0.00054 20.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CCD22501.1 - 7.4e-06 26.0 0.0 0.042 13.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 CCD22501.1 - 8.7e-06 25.7 2.1 0.17 11.6 0.2 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA PF00004.29 CCD22501.1 - 1.2e-05 25.7 0.0 0.04 14.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CCD22501.1 - 6.7e-05 22.5 0.8 0.18 11.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.15 CCD22501.1 - 0.00024 21.1 0.1 0.39 10.6 0.1 2.7 2 1 1 3 3 3 2 Rad17 P-loop domain Fer4_6 PF12837.7 CCD22501.1 - 0.00078 19.4 3.1 0.00078 19.4 3.1 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.7 CCD22501.1 - 0.001 19.6 0.4 0.001 19.6 0.4 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_23 PF13476.6 CCD22501.1 - 0.0013 19.3 4.7 0.015 15.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCD22501.1 - 0.0016 18.2 0.4 0.18 11.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 CCD22501.1 - 0.0022 17.8 1.5 0.47 10.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CCD22501.1 - 0.0023 17.2 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Fer4_21 PF14697.6 CCD22501.1 - 0.0025 17.9 12.6 0.0057 16.8 12.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain RNA_helicase PF00910.22 CCD22501.1 - 0.0028 18.0 0.0 1.1 9.7 0.0 2.9 3 0 0 3 3 2 1 RNA helicase NACHT PF05729.12 CCD22501.1 - 0.0038 17.1 0.9 0.43 10.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 CCD22501.1 - 0.0049 17.1 0.8 1 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.7 CCD22501.1 - 0.0056 16.7 0.8 0.0056 16.7 0.8 2.3 2 0 0 2 2 1 1 4Fe-4S binding domain Fer4_9 PF13187.6 CCD22501.1 - 0.0059 16.8 11.4 0.012 15.8 11.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_5 PF07728.14 CCD22501.1 - 0.0078 16.2 1.1 0.072 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CCD22501.1 - 0.0083 15.7 0.2 0.093 12.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region Fer4_10 PF13237.6 CCD22501.1 - 0.0087 16.2 1.6 0.0087 16.2 1.6 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_18 PF13238.6 CCD22501.1 - 0.0088 16.6 0.1 8.8 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CCD22501.1 - 0.0093 16.0 0.0 5 7.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain VirE PF05272.11 CCD22501.1 - 0.012 15.3 0.0 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E MMR_HSR1 PF01926.23 CCD22501.1 - 0.014 15.5 0.5 2.3 8.3 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 CCD22501.1 - 0.017 15.3 0.0 3.4 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CCD22501.1 - 0.02 14.9 0.1 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_16 PF13484.6 CCD22501.1 - 0.021 15.7 0.4 0.021 15.7 0.4 2.7 2 1 0 2 2 1 0 4Fe-4S double cluster binding domain dNK PF01712.19 CCD22501.1 - 0.022 14.6 0.0 0.35 10.7 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase SRP54 PF00448.22 CCD22501.1 - 0.031 13.9 3.4 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fer4_17 PF13534.6 CCD22501.1 - 0.063 13.8 0.1 0.063 13.8 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF815 PF05673.13 CCD22501.1 - 0.17 11.0 0.1 5.8 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Fer4_8 PF13183.6 CCD22501.1 - 0.17 12.4 0.1 0.17 12.4 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_13 PF13166.6 CCD22501.1 - 0.17 10.5 0.1 0.59 8.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CCD22501.1 - 0.2 11.2 0.5 2 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_4 PF12800.7 CCD22501.1 - 1.8 9.3 14.3 0.37 11.4 2.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain mRNA_triPase PF02940.15 CCD22502.1 - 1.4e-07 31.5 7.3 2.9e-07 30.4 7.3 1.6 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain PQ-loop PF04193.14 CCD22503.1 - 3.6e-23 81.1 11.8 1.1e-18 66.7 1.9 2.8 2 0 0 2 2 2 2 PQ loop repeat ABC2_membrane_5 PF13346.6 CCD22503.1 - 0.35 10.4 23.5 0.042 13.4 11.9 2.3 1 1 1 2 2 2 0 ABC-2 family transporter protein ATG19_autophagy PF12744.7 CCD22504.1 - 1.9e-13 50.2 9.9 7.7e-07 28.6 1.1 3.3 3 1 0 3 3 3 2 Autophagy protein Atg19, Atg8-binding DUF4796 PF16044.5 CCD22504.1 - 0.05 13.2 3.7 1.1 8.8 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4796) DUF5623 PF18536.1 CCD22504.1 - 0.17 12.2 4.4 0.24 11.7 0.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5623) ANTH PF07651.16 CCD22504.1 - 0.79 8.7 7.6 3.1 6.7 2.9 2.2 2 0 0 2 2 2 0 ANTH domain Chromate_transp PF02417.15 CCD22505.1 - 0.51 10.5 8.9 0.85 9.7 8.9 1.2 1 0 0 1 1 1 0 Chromate transporter Slu7 PF11708.8 CCD22506.1 - 2.5e-17 63.5 22.7 2.5e-17 63.5 22.7 2.8 2 2 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.23 CCD22506.1 - 0.0074 16.3 3.5 0.024 14.7 1.5 2.2 2 0 0 2 2 2 1 Zinc knuckle DUF234 PF03008.14 CCD22506.1 - 0.071 13.6 4.7 0.072 13.6 1.1 2.6 2 0 0 2 2 2 0 Archaea bacterial proteins of unknown function RPA_interact_N PF14766.6 CCD22506.1 - 0.11 12.2 2.9 3.1 7.5 0.5 2.6 2 0 0 2 2 2 0 Replication protein A interacting N-terminal PHD PF00628.29 CCD22506.1 - 0.15 12.0 0.9 0.35 10.8 0.9 1.6 1 0 0 1 1 1 0 PHD-finger Nop52 PF05997.12 CCD22507.1 - 2.2e-67 227.0 10.6 2.7e-67 226.7 10.6 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF846 PF05832.12 CCD22509.1 - 1.6e-45 154.6 8.5 2e-45 154.3 8.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Methyltransf_8 PF05148.15 CCD22510.1 - 1.9e-58 197.9 12.1 9.2e-34 117.2 0.1 3.4 3 1 1 4 4 4 3 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CCD22510.1 - 2.9e-06 27.9 0.0 1e-05 26.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCD22510.1 - 0.0034 18.0 0.0 0.012 16.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain CEL_III_C PF18054.1 CCD22510.1 - 0.38 10.8 2.6 0.7 9.9 2.6 1.4 1 0 0 1 1 1 0 CEL-III C-terminal Stn1_C PF12659.7 CCD22511.1 - 1.9e-35 121.4 14.0 1.9e-35 121.4 14.0 1.9 2 0 0 2 2 2 1 Telomere capping C-terminal wHTH Stn1 PF10451.9 CCD22511.1 - 3.4e-34 117.9 0.6 3.4e-34 117.9 0.6 2.1 2 0 0 2 2 2 1 Telomere regulation protein Stn1 ILEI PF15711.5 CCD22511.1 - 0.093 13.2 0.8 0.36 11.3 0.4 2.1 1 1 1 2 2 2 0 Interleukin-like EMT inducer DDE_1 PF03184.19 CCD22512.1 - 1.1e-67 227.1 1.8 2.9e-67 225.7 1.8 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CCD22512.1 - 6.3e-15 55.0 0.9 2.2e-14 53.2 0.2 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 CCD22512.1 - 3e-05 23.6 0.1 7.7e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_32 PF13565.6 CCD22512.1 - 0.17 12.5 0.0 1.1 9.9 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain Clathrin PF00637.20 CCD22513.1 - 1.6e-29 102.6 0.5 1.6e-29 102.6 0.5 2.9 2 1 0 2 2 2 1 Region in Clathrin and VPS Vps39_1 PF10366.9 CCD22513.1 - 5.4e-05 23.4 0.0 0.00019 21.7 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 WD40 PF00400.32 CCD22513.1 - 0.0031 18.3 0.4 0.014 16.3 0.4 2.3 1 0 0 1 1 1 1 WD domain, G-beta repeat Tfb5 PF06331.12 CCD22514.1 - 3.5e-25 87.8 0.1 3.9e-25 87.6 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Pet100 PF09803.9 CCD22515.1 - 6.7e-10 39.4 0.2 6.7e-10 39.4 0.2 1.5 2 0 0 2 2 2 1 Pet100 ATPase_gene1 PF09527.10 CCD22515.1 - 0.067 13.4 0.0 0.096 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF732 PF05305.14 CCD22517.1 - 0.5 10.8 3.6 5.5 7.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF732) ATPase PF06745.13 CCD22519.1 - 2.7e-08 33.4 1.9 3.1e-08 33.3 0.1 2.0 2 0 0 2 2 2 1 KaiC Rad51 PF08423.11 CCD22519.1 - 1.8e-06 27.4 0.1 6.5e-06 25.6 0.1 1.9 1 1 0 1 1 1 1 Rad51 ATPase_2 PF01637.18 CCD22519.1 - 0.0093 15.9 0.4 0.021 14.8 0.4 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DnaB_C PF03796.15 CCD22519.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.5 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain Bys1 PF04681.12 CCD22519.1 - 0.039 13.9 0.1 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 Blastomyces yeast-phase-specific protein AAA_25 PF13481.6 CCD22519.1 - 0.08 12.5 0.0 0.25 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CCD22519.1 - 0.21 11.8 1.0 3 8.1 1.0 2.4 1 1 0 1 1 1 0 AAA domain Glyco_transf_20 PF00982.21 CCD22520.1 - 1.5e-149 498.7 0.6 2.3e-149 498.1 0.6 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CCD22520.1 - 3.4e-80 268.5 0.0 6.9e-80 267.5 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase GlnE PF03710.15 CCD22521.1 - 0.037 13.4 0.2 0.05 13.0 0.2 1.1 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase PAP2_3 PF14378.6 CCD22522.1 - 3.7e-11 43.1 14.9 7.4e-10 38.8 4.1 2.6 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.21 CCD22522.1 - 1.3e-07 31.4 9.9 6.9e-05 22.6 0.8 2.9 3 0 0 3 3 3 2 PAP2 superfamily Acetyltransf_1 PF00583.25 CCD22523.1 - 6.3e-19 68.3 0.0 8.6e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCD22523.1 - 3.1e-12 46.5 0.0 4.4e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCD22523.1 - 3.3e-06 27.4 0.0 5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CCD22523.1 - 0.00064 19.2 0.0 0.00092 18.7 0.0 1.3 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 CCD22523.1 - 0.12 12.4 0.0 0.82 9.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CCD22523.1 - 0.17 11.5 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MEF2_binding PF09047.10 CCD22524.1 - 0.0097 15.7 0.1 0.019 14.8 0.1 1.5 1 0 0 1 1 1 1 MEF2 binding UCH PF00443.29 CCD22525.1 - 8.1e-59 199.2 2.3 8.1e-59 199.2 2.3 3.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCD22525.1 - 6.1e-20 72.0 2.7 6.1e-20 72.0 2.7 4.1 2 2 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 CCD22525.1 - 1.4e-07 32.0 0.0 6.9e-07 29.8 0.0 2.2 1 0 0 1 1 1 1 Rhodanese-like domain BSD PF03909.17 CCD22526.1 - 7.2e-15 54.7 0.2 2e-14 53.3 0.2 1.8 1 0 0 1 1 1 1 BSD domain DUF641 PF04859.12 CCD22526.1 - 0.15 12.4 7.2 0.72 10.2 1.6 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Y_phosphatase2 PF03162.13 CCD22527.1 - 3.2e-52 176.5 3.1 4.3e-51 172.8 3.1 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CCD22527.1 - 0.0014 18.7 0.0 0.0018 18.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family YABBY PF04690.13 CCD22527.1 - 0.034 14.7 1.6 3 8.4 0.1 2.2 2 0 0 2 2 2 0 YABBY protein VWA_N2 PF16164.5 CCD22527.1 - 0.068 13.3 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 VWA N-terminal YIEGIA PF14045.6 CCD22527.1 - 0.11 11.3 0.1 0.56 9.0 0.0 1.9 1 1 1 2 2 2 0 YIEGIA protein DSPc PF00782.20 CCD22527.1 - 0.11 12.3 4.5 1.2 8.9 0.1 3.0 2 1 1 3 3 3 0 Dual specificity phosphatase, catalytic domain NAD_binding_6 PF08030.12 CCD22527.1 - 0.21 11.7 4.5 0.13 12.4 1.8 1.8 2 0 0 2 2 2 0 Ferric reductase NAD binding domain RPAP2_Rtr1 PF04181.13 CCD22528.1 - 1.4e-10 41.3 0.0 2.7e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family TPR_22 PF18833.1 CCD22529.1 - 0.0082 16.3 0.9 0.047 13.8 0.3 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Complex1_LYR PF05347.15 CCD22529.1 - 0.1 12.7 1.7 0.16 12.0 0.2 2.2 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Cofilin_ADF PF00241.20 CCD22530.1 - 7.4e-17 61.3 0.0 8.9e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CLU_N PF15044.6 CCD22530.1 - 0.18 12.2 0.8 1.2 9.5 0.1 2.4 2 1 1 3 3 3 0 Mitochondrial function, CLU-N-term Aminotran_1_2 PF00155.21 CCD22531.1 - 7e-68 229.4 0.0 8.4e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 CCD22531.1 - 0.0073 15.1 0.0 0.015 14.0 0.0 1.4 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain ABC_tran PF00005.27 CCD22532.1 - 1.6e-23 83.7 1.0 5.2e-14 52.9 0.0 3.0 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 CCD22532.1 - 2.5e-07 30.8 1.1 0.0027 17.6 0.0 2.6 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CCD22532.1 - 0.00045 20.8 0.9 0.15 12.6 0.1 3.0 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.6 CCD22532.1 - 0.0021 17.7 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 CCD22532.1 - 0.046 13.9 0.0 3.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 CCD22532.1 - 0.067 13.5 0.1 3.6 7.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 CCD22532.1 - 0.2 10.7 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein LSM PF01423.22 CCD22533.1 - 2.2e-18 65.7 0.2 2.8e-18 65.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CCD22533.1 - 0.065 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Hfq protein zf-C2H2_10 PF16588.5 CCD22534.1 - 1.9e-14 53.1 5.2 2.9e-14 52.5 5.2 1.3 1 0 0 1 1 1 1 C2H2 zinc-finger DUF2538 PF10804.8 CCD22534.1 - 0.042 13.6 0.3 0.058 13.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2538) zf-CCHC_4 PF14392.6 CCD22534.1 - 0.32 10.8 2.7 0.49 10.2 1.8 1.7 2 0 0 2 2 2 0 Zinc knuckle dUTPase PF00692.19 CCD22535.1 - 1.1e-43 147.9 0.0 1.3e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 dUTPase Mog1 PF04603.12 CCD22536.1 - 2.8e-45 154.1 0.6 2.8e-45 154.1 0.6 1.7 2 0 0 2 2 2 1 Ran-interacting Mog1 protein DUF3439 PF11921.8 CCD22536.1 - 0.0088 16.0 4.9 0.019 14.9 4.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Gly_transf_sug PF04488.15 CCD22537.1 - 2.6e-13 50.4 0.9 1.1e-12 48.4 0.0 2.4 3 0 0 3 3 3 1 Glycosyltransferase sugar-binding region containing DXD motif HemX PF04375.14 CCD22537.1 - 0.026 13.8 3.3 0.042 13.1 3.3 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase TrbL PF04610.14 CCD22537.1 - 0.038 13.7 0.1 0.078 12.7 0.0 1.5 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein MRP-S32 PF10210.9 CCD22537.1 - 0.046 14.3 1.7 0.14 12.7 1.7 1.8 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 DUF4179 PF13786.6 CCD22537.1 - 0.047 14.2 0.1 0.098 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF2967 PF11179.8 CCD22537.1 - 0.056 11.5 3.3 0.073 11.2 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Mating_N PF12731.7 CCD22537.1 - 0.085 12.9 0.3 0.18 11.9 0.3 1.5 1 0 0 1 1 1 0 Mating-type protein beta 1 Peptidase_S49_N PF08496.10 CCD22537.1 - 0.093 12.8 3.7 0.15 12.1 3.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1640 PF07798.11 CCD22537.1 - 0.44 10.6 6.9 1 9.4 6.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) GLE1 PF07817.13 CCD22537.1 - 0.77 8.9 4.6 1.2 8.3 4.6 1.3 1 0 0 1 1 1 0 GLE1-like protein DUF1514 PF07438.11 CCD22537.1 - 1.5 8.7 5.4 0.73 9.8 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) DUF4446 PF14584.6 CCD22537.1 - 2.3 8.2 5.0 4.9 7.1 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Syja_N PF02383.18 CCD22538.1 - 1.7e-85 287.1 2.6 2.8e-85 286.5 2.6 1.3 1 0 0 1 1 1 1 SacI homology domain Flavodoxin_2 PF02525.17 CCD22539.1 - 4.5e-50 170.1 0.0 6.4e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CCD22539.1 - 1.6e-12 47.5 0.0 3.7e-12 46.2 0.0 1.6 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Mito_carr PF00153.27 CCD22540.1 - 1.2e-44 150.1 6.3 4.6e-17 61.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S2 PF00318.20 CCD22541.1 - 5.9e-68 228.3 0.0 3.6e-67 225.7 0.0 2.1 2 1 0 2 2 2 1 Ribosomal protein S2 Ribosomal_L10 PF00466.20 CCD22543.1 - 9e-21 73.9 0.2 1.3e-20 73.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 CCD22543.1 - 7.4e-19 67.5 0.0 1.2e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Pkinase PF00069.25 CCD22544.1 - 6.3e-71 238.8 0.0 1.5e-70 237.6 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22544.1 - 6e-46 156.8 0.0 1.2e-45 155.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CCD22544.1 - 1.4e-16 60.6 0.2 5.5e-16 58.7 0.2 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 CCD22544.1 - 3.5e-05 22.8 0.0 3.5e-05 22.8 0.0 2.2 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 CCD22544.1 - 0.00052 19.4 0.0 0.0018 17.7 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 CCD22544.1 - 0.23 11.3 0.0 0.74 9.7 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Flavodoxin_2 PF02525.17 CCD22545.1 - 3.5e-54 183.5 0.0 4.6e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CCD22545.1 - 3e-12 46.6 0.0 7.1e-12 45.3 0.0 1.6 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.7 CCD22545.1 - 0.17 11.6 0.3 0.36 10.5 0.3 1.7 1 1 0 1 1 1 0 Flavodoxin SRP1_TIP1 PF00660.17 CCD22546.1 - 4.3e-36 123.0 0.3 4.3e-36 123.0 0.3 2.0 2 1 1 3 3 3 1 Seripauperin and TIP1 family PEMT PF04191.13 CCD22547.1 - 2.6e-34 117.8 3.1 2.6e-34 117.8 3.1 1.8 3 0 0 3 3 3 1 Phospholipid methyltransferase PAC2 PF09754.9 CCD22548.1 - 3.6e-22 79.4 0.0 4.5e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 PAC2 family AAA PF00004.29 CCD22551.1 - 7.4e-17 62.0 0.0 1.5e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CCD22551.1 - 3.8e-15 56.0 0.0 9.1e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CCD22551.1 - 1.5e-13 50.9 0.0 8.1e-12 45.2 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 CCD22551.1 - 3.6e-08 33.6 0.2 1e-07 32.1 0.0 1.9 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 CCD22551.1 - 1.4e-05 25.3 0.0 4.3e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain RuvB_N PF05496.12 CCD22551.1 - 1.6e-05 24.7 0.0 4.5e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCD22551.1 - 4.2e-05 23.8 0.0 0.00054 20.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CCD22551.1 - 4.5e-05 23.4 0.0 0.0001 22.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCD22551.1 - 8.7e-05 23.0 0.0 0.0044 17.4 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 CCD22551.1 - 0.00024 21.2 0.0 0.00078 19.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CCD22551.1 - 0.00094 18.6 0.0 0.017 14.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CCD22551.1 - 0.0033 17.8 0.0 0.011 16.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCD22551.1 - 0.0034 17.1 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CCD22551.1 - 0.0036 16.5 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 CCD22551.1 - 0.0043 16.6 0.0 0.01 15.3 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CCD22551.1 - 0.0071 16.7 0.0 0.24 11.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 CCD22551.1 - 0.0078 16.0 0.0 0.028 14.2 0.0 1.9 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 CCD22551.1 - 0.009 16.0 0.0 0.048 13.7 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 CCD22551.1 - 0.015 15.3 0.3 0.13 12.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CCD22551.1 - 0.028 15.0 0.0 0.081 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CCD22551.1 - 0.029 14.2 0.0 0.24 11.3 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CCD22551.1 - 0.03 14.8 0.0 0.052 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CCD22551.1 - 0.036 13.3 0.0 0.12 11.5 0.0 1.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 CCD22551.1 - 0.048 13.9 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1938 PF09153.10 CCD22551.1 - 0.055 13.6 0.6 0.85 9.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1938) TIP49_C PF17856.1 CCD22551.1 - 0.057 13.6 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 TIP49 AAA-lid domain DNA_pol3_gamma3 PF12169.8 CCD22551.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III Yae1_N PF09811.9 CCD22552.1 - 6.7e-13 48.1 0.0 1e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal FAT PF02259.23 CCD22553.1 - 3.9e-120 401.2 5.5 7.5e-120 400.3 5.5 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 CCD22553.1 - 2.9e-70 236.9 1.6 4.1e-70 236.4 0.1 2.1 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 CCD22553.1 - 6.4e-62 208.2 14.3 1.2e-57 194.3 1.3 4.2 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CCD22553.1 - 1.4e-39 134.5 6.3 5.9e-39 132.5 2.8 3.0 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 CCD22553.1 - 4.4e-16 58.4 0.1 1.1e-15 57.2 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 CCD22553.1 - 6.2e-11 41.6 0.6 0.035 14.3 0.0 8.6 9 0 0 9 9 8 1 HEAT repeat HEAT_2 PF13646.6 CCD22553.1 - 1.1e-09 38.5 2.1 0.034 14.6 0.0 6.5 6 1 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 CCD22553.1 - 0.0011 19.4 6.5 5.7 7.6 0.0 7.6 8 2 3 11 11 9 1 HEAT-like repeat CLASP_N PF12348.8 CCD22553.1 - 0.0042 16.7 15.7 0.09 12.3 0.1 5.2 5 1 0 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 CCD22553.1 - 0.027 15.1 15.9 1.1 9.9 0.0 6.0 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region DUF3437 PF11919.8 CCD22553.1 - 0.065 13.1 0.0 18 5.3 0.0 4.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) DUF3453 PF11935.8 CCD22553.1 - 0.25 11.0 5.9 1.3 8.7 0.3 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3453) Actin PF00022.19 CCD22554.1 - 1.5e-90 303.7 0.0 3.8e-88 295.8 0.0 2.1 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CCD22554.1 - 2e-05 23.6 0.0 0.0074 15.1 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CCD22554.1 - 0.00027 21.3 0.1 0.003 18.0 0.0 2.5 2 1 0 2 2 2 1 Cell division protein FtsA Cpn60_TCP1 PF00118.24 CCD22555.1 - 4.7e-151 503.8 3.9 5.3e-151 503.6 3.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.12 CCD22555.1 - 0.0089 15.9 1.3 2.7 7.8 0.1 2.9 2 1 0 2 2 2 2 Chloramphenicol phosphotransferase-like protein Cation_ATPase PF13246.6 CCD22555.1 - 0.048 13.7 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Cation transport ATPase (P-type) TFIIS_C PF01096.18 CCD22556.1 - 9.2e-19 67.0 1.1 9.2e-19 67.0 1.1 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CCD22556.1 - 4e-13 49.0 10.2 1.1e-09 38.0 1.2 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 CCD22556.1 - 8.4e-06 25.7 6.5 0.0057 16.7 0.3 2.7 2 1 0 2 2 2 2 Double zinc ribbon zinc_ribbon_4 PF13717.6 CCD22556.1 - 0.00092 19.1 8.7 0.43 10.6 0.2 3.7 4 0 0 4 4 3 1 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 CCD22556.1 - 0.00097 19.1 2.3 0.007 16.3 0.2 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 CCD22556.1 - 0.0017 18.4 10.5 0.42 10.8 0.5 3.3 3 0 0 3 3 3 1 Zinc ribbon domain zf-TFIIB PF13453.6 CCD22556.1 - 0.0019 17.5 2.5 0.015 14.6 0.7 2.4 2 0 0 2 2 2 1 Transcription factor zinc-finger zinc_ribbon_2 PF13240.6 CCD22556.1 - 0.0071 16.0 15.0 0.35 10.7 0.6 4.4 4 1 0 4 4 4 1 zinc-ribbon domain IBR PF01485.21 CCD22556.1 - 0.0083 16.3 6.8 1.1 9.5 1.8 2.5 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain DpnI PF06044.12 CCD22556.1 - 0.013 15.1 4.7 0.31 10.6 0.5 2.1 1 1 1 2 2 2 0 Dam-replacing family zf-H2C2_2 PF13465.6 CCD22556.1 - 0.013 15.9 5.1 0.39 11.2 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double domain TF_Zn_Ribbon PF08271.12 CCD22556.1 - 0.017 14.7 2.5 0.017 14.7 2.5 2.9 2 2 0 2 2 2 0 TFIIB zinc-binding DUF523 PF04463.12 CCD22556.1 - 0.02 14.9 0.1 0.022 14.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF523) Ogr_Delta PF04606.12 CCD22556.1 - 0.025 14.6 2.0 0.025 14.6 2.0 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Baculo_p48 PF04878.13 CCD22556.1 - 0.03 13.3 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 Baculovirus P48 protein zf-C4_Topoisom PF01396.19 CCD22556.1 - 0.038 13.8 2.1 0.038 13.8 2.1 3.2 3 1 0 3 3 2 0 Topoisomerase DNA binding C4 zinc finger Lar_restr_allev PF14354.6 CCD22556.1 - 0.042 14.2 7.3 0.37 11.2 0.9 3.0 2 1 0 2 2 2 0 Restriction alleviation protein Lar Mu-like_Com PF10122.9 CCD22556.1 - 0.044 13.2 0.4 3.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-ribbon_3 PF13248.6 CCD22556.1 - 0.05 13.0 14.2 1.6 8.3 0.5 4.3 4 0 0 4 4 4 0 zinc-ribbon domain Baculo_LEF5_C PF11792.8 CCD22556.1 - 0.078 12.7 3.4 0.15 11.8 0.0 2.7 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain HypA PF01155.19 CCD22556.1 - 0.082 12.9 7.4 9.1 6.3 7.7 2.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA tRNA-synt_1f PF01921.18 CCD22556.1 - 0.095 11.6 0.4 0.12 11.3 0.4 1.2 1 1 0 1 1 1 0 tRNA synthetases class I (K) C1_1 PF00130.22 CCD22556.1 - 0.11 12.4 4.3 1.4 8.9 0.2 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GATA PF00320.27 CCD22556.1 - 0.16 11.6 0.3 0.16 11.6 0.3 2.9 3 1 0 3 3 3 0 GATA zinc finger DUF2072 PF09845.9 CCD22556.1 - 0.26 11.6 0.3 0.26 11.6 0.3 2.7 1 1 2 3 3 3 0 Zn-ribbon containing protein eIF-5_eIF-2B PF01873.17 CCD22556.1 - 0.31 10.9 4.4 0.52 10.2 0.4 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 CpXC PF14353.6 CCD22556.1 - 0.33 11.0 0.1 0.33 11.0 0.1 3.2 2 1 1 4 4 3 0 CpXC protein OrfB_Zn_ribbon PF07282.11 CCD22556.1 - 1.2 9.1 7.4 14 5.7 0.2 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Nudix_N_2 PF14803.6 CCD22556.1 - 2.3 8.2 10.0 4.5 7.3 1.4 3.7 3 1 0 3 3 3 0 Nudix N-terminal DNA_RNApol_7kD PF03604.13 CCD22556.1 - 2.3 8.0 9.8 12 5.7 0.2 3.8 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Stc1 PF12898.7 CCD22556.1 - 2.4 8.8 9.2 0.65 10.6 1.4 2.4 1 1 1 2 2 2 0 Stc1 domain zf-AN1 PF01428.16 CCD22556.1 - 2.8 8.2 9.7 17 5.7 0.2 3.6 3 1 0 3 3 3 0 AN1-like Zinc finger DUF983 PF06170.12 CCD22556.1 - 3.1 8.3 5.8 74 3.8 3.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF983) Ribosomal_S27e PF01667.17 CCD22556.1 - 5.2 6.8 10.4 25 4.7 0.0 3.8 3 1 0 3 3 3 0 Ribosomal protein S27 zf-RRN7 PF11781.8 CCD22556.1 - 8.3 6.2 12.2 11 5.8 0.0 3.7 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn_ribbon_SprT PF17283.2 CCD22556.1 - 9 6.3 14.3 5.2 7.1 1.4 3.9 4 0 0 4 4 4 0 SprT-like zinc ribbon domain zinc_ribbon_15 PF17032.5 CCD22556.1 - 9.3 7.1 12.0 72 4.2 1.7 3.2 1 1 1 2 2 2 0 zinc-ribbon family PRCC PF10253.9 CCD22557.1 - 0.015 16.1 0.3 0.018 15.9 0.3 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Dynactin_p22 PF07426.11 CCD22557.1 - 0.07 13.0 0.4 0.1 12.5 0.4 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 CN_hydrolase PF00795.22 CCD22558.1 - 3e-17 62.8 0.0 5.7e-15 55.3 0.0 2.6 3 0 0 3 3 3 2 Carbon-nitrogen hydrolase LicD PF04991.13 CCD22559.1 - 6.3e-49 167.1 1.5 6.3e-49 167.1 1.5 2.6 2 0 0 2 2 2 1 LicD family DUF1192 PF06698.11 CCD22559.1 - 0.11 12.5 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) HLH PF00010.26 CCD22560.1 - 1.2e-13 50.8 2.0 2.8e-13 49.6 2.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SlyX PF04102.12 CCD22560.1 - 1.2 9.8 6.7 2.5 8.8 2.8 2.9 2 0 0 2 2 2 0 SlyX Pkinase PF00069.25 CCD22561.1 - 3.4e-35 121.7 0.0 5.7e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22561.1 - 1.8e-13 50.4 0.0 3.4e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CCD22561.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCD22561.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Nore1-SARAH PF16517.5 CCD22562.1 - 0.032 14.1 5.9 0.35 10.8 0.6 3.2 3 0 0 3 3 3 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain RT_RNaseH PF17917.1 CCD22563.1 - 5.9e-22 77.9 0.0 3e-21 75.7 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CCD22563.1 - 1.8e-16 60.0 0.0 1.1e-08 35.0 0.0 2.9 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 CCD22563.1 - 2.3e-15 56.8 0.0 8.5e-15 55.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CCD22563.1 - 3.4e-15 56.2 0.1 9.4e-15 54.7 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CCD22563.1 - 2.2e-08 34.1 0.9 2.2e-08 34.1 0.9 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 CCD22563.1 - 0.01 16.4 0.0 0.05 14.2 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 CCD22563.1 - 0.051 13.8 0.2 0.18 12.1 0.2 2.0 1 0 0 1 1 1 0 H2C2 zinc finger RVP PF00077.20 CCD22563.1 - 0.059 13.7 0.0 0.22 11.8 0.0 2.1 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CCD22563.1 - 0.065 13.9 0.0 0.24 12.0 0.0 2.1 1 0 0 1 1 1 0 Aspartyl protease Asp PF00026.23 CCD22563.1 - 0.069 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic aspartyl protease Peptidase_A2B PF12384.8 CCD22563.1 - 0.49 9.9 5.4 0.22 11.0 0.1 2.9 4 0 0 4 4 4 0 Ty3 transposon peptidase RRM_5 PF13893.6 CCD22564.1 - 3.9e-10 39.4 0.0 4.3e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CCD22564.1 - 2.7e-08 33.5 0.2 6.5e-08 32.3 0.2 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IMS PF00817.20 CCD22565.1 - 2.7e-43 147.6 0.0 4.8e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 CCD22565.1 - 4.3e-08 32.6 1.8 4.3e-08 32.6 1.8 2.0 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 CCD22565.1 - 1.6e-05 24.9 0.0 5.1e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif zf-C2HE PF16278.5 CCD22565.1 - 0.0079 16.6 2.5 0.024 15.1 1.3 2.5 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger Ribosomal_L11_N PF03946.14 CCD22566.1 - 1.4e-21 76.0 1.4 1.9e-21 75.6 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CCD22566.1 - 9.8e-17 61.2 1.3 1.9e-16 60.3 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain TPR_14 PF13428.6 CCD22567.1 - 8.2e-09 35.6 0.0 0.054 14.3 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCD22567.1 - 4e-06 27.3 0.2 5.5 7.6 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCD22567.1 - 4.3e-06 26.9 0.2 0.52 10.6 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCD22567.1 - 2.2e-05 24.3 12.5 0.001 19.1 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 CCD22567.1 - 3.3e-05 23.7 2.9 0.097 12.8 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 CCD22567.1 - 0.0011 18.9 2.6 0.66 10.0 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.10 CCD22567.1 - 0.0018 17.4 0.8 0.0018 17.4 0.8 5.7 4 2 1 5 5 5 1 NRDE-2, necessary for RNA interference TPR_7 PF13176.6 CCD22567.1 - 0.0064 16.4 4.5 12 6.2 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD22567.1 - 0.012 15.8 3.9 1.2 9.5 0.0 4.2 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CCD22567.1 - 0.021 14.7 5.0 0.53 10.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CCD22567.1 - 0.032 14.2 26.9 0.24 11.4 0.5 7.2 6 2 2 8 8 7 0 Mad3/BUB1 homology region 1 TPR_6 PF13174.6 CCD22567.1 - 0.12 13.0 0.5 1.1e+02 3.7 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CCD22567.1 - 0.13 12.1 5.0 5 7.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCD22567.1 - 0.17 12.6 0.0 3.3 8.4 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 CCD22567.1 - 0.26 11.4 3.0 42 4.3 0.1 4.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain HAT PF02184.16 CCD22567.1 - 1.9 8.5 6.9 31 4.7 0.0 4.8 6 0 0 6 6 5 0 HAT (Half-A-TPR) repeat ATP-synt_D PF01813.17 CCD22568.1 - 4.4e-70 235.5 3.5 4.4e-70 235.5 3.5 1.4 2 0 0 2 2 2 1 ATP synthase subunit D ISG65-75 PF11727.8 CCD22568.1 - 0.18 11.0 10.3 0.52 9.5 7.6 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein Ribosomal_L6e PF01159.19 CCD22568.1 - 1.8 9.1 8.5 0.54 10.8 5.1 1.9 2 0 0 2 2 2 0 Ribosomal protein L6e Peptidase_M28 PF04389.17 CCD22569.1 - 1.7e-26 93.1 0.0 2e-25 89.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 CCD22569.1 - 0.00058 19.6 0.0 0.001 18.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 EXS PF03124.14 CCD22570.1 - 4e-56 190.7 23.5 4.7e-56 190.5 23.5 1.0 1 0 0 1 1 1 1 EXS family Nop25 PF09805.9 CCD22571.1 - 5.8e-40 136.9 20.4 5.8e-40 136.9 20.4 2.6 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) KNTase_C PF07827.11 CCD22571.1 - 0.035 13.9 0.1 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 KNTase C-terminal domain DER1 PF04511.15 CCD22572.1 - 4.9e-39 134.3 6.4 6e-39 134.0 6.4 1.1 1 0 0 1 1 1 1 Der1-like family ICMT PF04140.14 CCD22573.1 - 1.4e-29 102.3 0.2 2.3e-29 101.6 0.2 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CCD22573.1 - 5.9e-14 52.4 5.3 3.2e-13 50.0 0.5 2.8 2 1 1 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.12 CCD22573.1 - 9.9e-05 22.0 0.3 0.00014 21.5 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 CCD22573.1 - 0.028 13.9 0.0 0.063 12.8 0.0 1.6 1 1 0 1 1 1 0 NnrU protein Rab5ip PF07019.12 CCD22573.1 - 6.5 7.4 10.4 42 4.8 10.1 2.6 1 1 1 2 2 2 0 Rab5-interacting protein (Rab5ip) PINIT PF14324.6 CCD22574.1 - 4.6e-36 124.3 0.3 1.2e-35 123.0 0.3 1.7 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 CCD22574.1 - 3.6e-20 71.5 8.4 7.1e-20 70.5 8.4 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CCD22574.1 - 6.2e-05 22.7 0.7 0.00016 21.5 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CCD22574.1 - 0.00033 20.6 2.9 0.00065 19.7 2.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CCD22574.1 - 1.3 9.5 4.6 2.3 8.6 4.6 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 CCD22574.1 - 2.5 8.0 4.4 5.5 6.9 4.4 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Formyl_trans_N PF00551.19 CCD22575.1 - 1.2e-51 175.0 0.0 1.4e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase TRAPPC9-Trs120 PF08626.11 CCD22576.1 - 0 1046.4 23.1 0 1046.1 23.1 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit ABC2_membrane PF01061.24 CCD22577.1 - 1.8e-84 282.4 51.2 7e-45 153.0 22.0 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 CCD22577.1 - 1.8e-38 132.1 0.1 1.8e-17 64.2 0.0 3.4 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 CCD22577.1 - 8.4e-36 121.8 0.9 5e-31 106.5 0.1 3.4 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CCD22577.1 - 7.7e-17 61.7 0.4 3.8e-16 59.5 0.0 2.5 3 0 0 3 3 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 CCD22577.1 - 4.1e-07 29.8 1.3 2.7e-05 23.8 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CCD22577.1 - 2.8e-06 27.8 0.1 0.00036 20.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 CCD22577.1 - 4e-06 27.4 0.2 0.0078 16.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.7 CCD22577.1 - 4.8e-06 25.9 29.1 0.0015 17.8 7.2 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CCD22577.1 - 2.4e-05 24.3 0.5 0.00087 19.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CCD22577.1 - 0.0011 18.6 2.6 0.009 15.7 0.1 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 CCD22577.1 - 0.0013 18.2 0.0 0.14 11.6 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 CCD22577.1 - 0.0024 18.2 2.2 0.28 11.4 0.3 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CCD22577.1 - 0.0024 17.7 0.0 0.44 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 CCD22577.1 - 0.0025 18.0 0.0 0.18 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CCD22577.1 - 0.0074 16.6 3.1 0.57 10.5 0.3 3.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CCD22577.1 - 0.0084 15.8 1.0 3.9 7.1 0.5 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CCD22577.1 - 0.009 15.9 1.9 3.4 7.6 0.2 2.8 3 0 0 3 3 2 2 NACHT domain OCD_Mu_crystall PF02423.15 CCD22577.1 - 0.014 14.4 0.0 0.42 9.5 0.0 2.4 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family cobW PF02492.19 CCD22577.1 - 0.016 14.8 2.1 2.1 7.9 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 CCD22577.1 - 0.069 13.6 0.3 0.069 13.6 0.3 3.0 3 0 0 3 3 3 0 AAA domain DnaB_C PF03796.15 CCD22577.1 - 0.073 12.4 0.1 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA PF00004.29 CCD22577.1 - 0.12 12.7 0.1 25 5.3 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CCD22577.1 - 0.14 11.8 0.3 7.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 CCD22577.1 - 0.16 11.9 0.0 24 4.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) dNK PF01712.19 CCD22577.1 - 0.26 11.1 2.4 15 5.4 0.0 2.9 3 0 0 3 3 3 0 Deoxynucleoside kinase Ribosomal_L23 PF00276.20 CCD22579.1 - 1.5e-10 41.2 0.0 5.5e-10 39.5 0.0 1.9 3 0 0 3 3 3 1 Ribosomal protein L23 S1 PF00575.23 CCD22580.1 - 4.9e-18 65.3 0.1 7e-18 64.8 0.1 1.2 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 CCD22580.1 - 1.6e-16 60.4 0.0 3.3e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 CCD22580.1 - 8.7e-06 26.0 0.0 1.5e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 DIT1_PvcA PF05141.12 CCD22581.1 - 2.6e-98 328.9 0.0 4.4e-98 328.2 0.0 1.4 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.22 CCD22582.1 - 4e-43 147.8 0.2 5.4e-43 147.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 IU_nuc_hydro PF01156.19 CCD22583.1 - 4.5e-70 236.6 0.0 5.3e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Pribosyltran PF00156.27 CCD22584.1 - 4e-09 36.2 0.2 8.2e-09 35.2 0.2 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Fe-ADH PF00465.19 CCD22584.1 - 0.042 12.6 0.0 0.077 11.8 0.0 1.4 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase 3Beta_HSD PF01073.19 CCD22584.1 - 0.11 11.5 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family IBN_N PF03810.19 CCD22585.1 - 9.1e-17 60.7 0.2 3.8e-16 58.7 0.2 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Npa1 PF11707.8 CCD22585.1 - 0.042 13.2 2.3 0.38 10.1 0.0 3.5 5 0 0 5 5 5 0 Ribosome 60S biogenesis N-terminal Vac14_Fab1_bd PF12755.7 CCD22585.1 - 0.19 12.3 1.0 1.2 9.8 0.1 3.0 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF445 PF04286.12 CCD22585.1 - 1.3 8.7 4.8 2.2 8.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF445) AAA PF00004.29 CCD22586.1 - 3.8e-46 156.8 0.0 1.1e-45 155.2 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CCD22586.1 - 7.4e-09 35.4 0.1 5.8e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CCD22586.1 - 3.3e-08 33.8 0.0 6.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CCD22586.1 - 1.6e-07 31.9 0.1 3.4e-05 24.3 0.0 3.2 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CCD22586.1 - 1.6e-07 31.4 0.1 6.5e-07 29.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCD22586.1 - 5.6e-05 23.4 2.8 0.0043 17.3 0.0 3.0 2 1 0 3 3 3 1 AAA domain DUF815 PF05673.13 CCD22586.1 - 5.7e-05 22.4 0.0 9.7e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CCD22586.1 - 0.00044 20.0 0.0 0.0012 18.6 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 CCD22586.1 - 0.00045 20.0 0.2 0.0012 18.7 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 CCD22586.1 - 0.00079 20.0 0.0 0.0072 16.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 CCD22586.1 - 0.00082 19.3 0.2 0.0028 17.6 0.0 2.0 3 0 0 3 3 2 1 NTPase RNA_helicase PF00910.22 CCD22586.1 - 0.0019 18.6 0.0 0.0039 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 CCD22586.1 - 0.002 18.2 0.1 0.0075 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CCD22586.1 - 0.0021 18.1 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CCD22586.1 - 0.0028 17.2 0.0 0.026 14.0 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 CCD22586.1 - 0.0029 17.4 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CCD22586.1 - 0.003 17.4 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 CCD22586.1 - 0.0037 16.5 0.0 0.0066 15.7 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_30 PF13604.6 CCD22586.1 - 0.0043 16.8 0.0 0.012 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CCD22586.1 - 0.0056 16.8 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 CCD22586.1 - 0.0059 16.0 0.1 0.44 9.9 0.0 2.5 3 0 0 3 3 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 CCD22586.1 - 0.0069 15.8 0.1 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CCD22586.1 - 0.0096 15.6 0.0 0.19 11.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 CCD22586.1 - 0.012 15.5 0.1 0.12 12.3 0.0 2.4 1 1 1 2 2 2 0 NACHT domain AAA_28 PF13521.6 CCD22586.1 - 0.015 15.6 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CCD22586.1 - 0.025 14.5 0.1 0.37 10.7 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 CCD22586.1 - 0.026 14.3 0.2 0.075 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CCD22586.1 - 0.029 14.1 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein MCM PF00493.23 CCD22586.1 - 0.056 12.5 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 MCM P-loop domain AAA_19 PF13245.6 CCD22586.1 - 0.11 12.8 0.1 0.37 11.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 CCD22586.1 - 0.13 11.9 1.3 0.48 10.0 0.1 2.3 2 1 0 3 3 3 0 AAA domain DnaB_C PF03796.15 CCD22586.1 - 1.5 8.1 5.3 3.1 7.1 0.9 2.7 2 1 0 3 3 3 0 DnaB-like helicase C terminal domain She9_MDM33 PF05546.11 CCD22587.1 - 8.4e-87 290.1 23.4 4.8e-86 287.6 11.8 2.3 2 0 0 2 2 2 2 She9 / Mdm33 family zf-RING_9 PF13901.6 CCD22587.1 - 0.012 15.6 1.2 0.012 15.6 1.2 2.0 1 1 0 2 2 2 0 Putative zinc-RING and/or ribbon Erf4 PF10256.9 CCD22587.1 - 0.38 10.9 3.0 0.76 9.9 0.8 2.7 2 2 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Peptidase_C12 PF01088.21 CCD22587.1 - 1.4 8.6 7.6 0.21 11.3 2.8 1.9 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase, family 1 PhoU_div PF01865.16 CCD22587.1 - 6.2 6.1 13.4 0.41 9.9 0.1 3.7 3 1 1 4 4 4 0 Protein of unknown function DUF47 KH_8 PF17903.1 CCD22588.1 - 7e-06 26.0 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CCD22588.1 - 0.13 12.2 0.3 0.35 10.7 0.3 1.8 1 0 0 1 1 1 0 KH domain TFIID-18kDa PF02269.16 CCD22589.1 - 2e-37 127.1 0.2 1.7e-36 124.1 0.1 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit ThiF PF00899.21 CCD22590.1 - 2.2e-69 233.5 0.0 2.9e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 CCD22590.1 - 1.8e-06 28.0 9.7 6.2e-05 23.0 0.5 2.6 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site Tfb5 PF06331.12 CCD22590.1 - 8e-05 22.6 0.0 0.00023 21.1 0.0 1.8 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Shikimate_DH PF01488.20 CCD22590.1 - 0.086 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CCD22590.1 - 0.13 12.8 0.0 0.6 10.6 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding RhoGAP PF00620.27 CCD22591.1 - 3.8e-31 108.0 0.1 1.1e-19 70.8 0.0 3.2 3 0 0 3 3 3 2 RhoGAP domain Syntaxin_2 PF14523.6 CCD22591.1 - 4.6 7.7 10.3 0.32 11.4 4.4 2.2 2 0 0 2 2 2 0 Syntaxin-like protein RR_TM4-6 PF06459.12 CCD22591.1 - 9.5 6.0 11.2 0.48 10.2 4.2 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 BAR PF03114.18 CCD22592.1 - 2e-65 220.8 6.8 2.5e-65 220.5 6.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 CCD22592.1 - 6.5e-15 54.5 0.1 1.1e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCD22592.1 - 2.2e-12 46.6 0.1 3.7e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCD22592.1 - 1.9e-07 30.6 0.0 3.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF755 PF05501.11 CCD22592.1 - 0.064 13.5 0.9 0.15 12.3 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Mis14 PF08641.12 CCD22592.1 - 8.9 6.6 8.8 1.7 8.9 0.5 2.3 2 0 0 2 2 2 0 Kinetochore protein Mis14 like Sugar_tr PF00083.24 CCD22593.1 - 7.6e-98 328.3 25.4 6.5e-53 180.2 6.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CCD22593.1 - 3.1e-33 115.2 39.4 6.7e-29 100.9 18.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily GPI2 PF06432.11 CCD22593.1 - 0.0088 15.5 3.5 0.0088 15.5 3.5 2.6 2 1 1 3 3 3 1 Phosphatidylinositol N-acetylglucosaminyltransferase Phage_holin_3_2 PF04550.12 CCD22593.1 - 0.076 13.6 8.4 0.12 12.9 2.6 3.2 3 1 0 3 3 3 0 Phage holin family 2 ERCC4 PF02732.15 CCD22594.1 - 1.6e-19 70.6 0.3 5.1e-19 69.0 0.3 1.9 1 0 0 1 1 1 1 ERCC4 domain HHH_3 PF12836.7 CCD22594.1 - 0.025 14.8 0.3 0.093 13.0 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif rve PF00665.26 CCD22595.1 - 1.3e-15 57.7 0.0 2.3e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CCD22595.1 - 2.1e-09 37.3 1.0 5.2e-09 36.1 1.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CCD22595.1 - 0.016 15.4 0.2 0.044 14.0 0.2 1.8 1 0 0 1 1 1 0 H2C2 zinc finger rve_3 PF13683.6 CCD22595.1 - 0.18 11.6 1.8 0.25 11.2 0.1 2.2 2 0 0 2 2 2 0 Integrase core domain GTP_EFTU PF00009.27 CCD22596.1 - 5.9e-68 228.2 0.3 8.4e-68 227.7 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CCD22596.1 - 2.4e-33 114.5 0.0 1.1e-32 112.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CCD22596.1 - 4.2e-22 78.0 0.0 1.2e-21 76.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CCD22596.1 - 5.8e-14 52.0 0.0 2.5e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CCD22596.1 - 1.2e-12 48.0 0.1 5.5e-12 45.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCD22596.1 - 0.00014 21.9 0.1 0.00029 20.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gpr1_Fun34_YaaH PF01184.19 CCD22597.1 - 7.6e-77 257.6 14.8 9.5e-77 257.3 14.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Mito_carr PF00153.27 CCD22598.1 - 9.9e-58 192.1 4.2 3.9e-19 68.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TMEM141 PF15110.6 CCD22598.1 - 0.012 16.2 0.2 0.15 12.7 0.1 2.3 2 0 0 2 2 2 0 TMEM141 protein family RRM_1 PF00076.22 CCD22600.1 - 4.7e-12 45.6 0.0 8.7e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GTA_holin_3TM PF11351.8 CCD22600.1 - 0.15 12.6 3.5 0.34 11.4 3.5 1.5 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Spt20 PF12090.8 CCD22600.1 - 0.16 11.6 10.0 0.24 11.0 10.0 1.4 1 0 0 1 1 1 0 Spt20 family TPP_enzyme_C PF02775.21 CCD22601.1 - 1.3e-14 54.2 0.0 3.4e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCD22601.1 - 2.5e-14 53.2 0.0 4.7e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 CCD22601.1 - 5.3e-10 39.2 0.0 1.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Complex1_LYR PF05347.15 CCD22602.1 - 4.7e-14 52.2 0.7 5.5e-14 52.0 0.7 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CCD22602.1 - 0.0011 19.7 0.4 0.0012 19.6 0.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like RhoGAP PF00620.27 CCD22603.1 - 4.6e-36 123.9 0.1 8e-36 123.2 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain LSM PF01423.22 CCD22604.1 - 3.7e-17 61.8 0.1 4.4e-17 61.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CCD22604.1 - 0.0016 18.5 0.0 0.0022 18.1 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CCD22604.1 - 0.014 15.5 0.1 0.017 15.2 0.1 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain F1F0-ATPsyn_F PF10791.9 CCD22605.1 - 9.2e-40 135.0 0.2 1e-39 134.9 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 CCD22605.1 - 0.013 15.9 0.0 0.015 15.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Pyr_redox_2 PF07992.14 CCD22606.1 - 3.1e-08 33.2 0.0 6.8e-08 32.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CCD22606.1 - 1.2e-05 25.5 0.0 3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CCD22606.1 - 0.0042 17.1 0.0 0.012 15.6 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 CCD22606.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CCD22606.1 - 0.037 13.1 0.0 0.75 8.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 CCD22606.1 - 0.043 13.9 0.0 13 5.8 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase YTH PF04146.15 CCD22608.1 - 1.5e-36 125.8 3.5 6.2e-36 123.8 3.5 1.9 1 1 0 1 1 1 1 YT521-B-like domain EVE PF01878.18 CCD22608.1 - 0.049 13.6 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 EVE domain PYST-C1 PF09690.10 CCD22608.1 - 0.1 12.3 2.4 3 7.7 0.3 2.7 2 0 0 2 2 2 0 Plasmodium yoelii subtelomeric region (PYST-C1) Ammonium_transp PF00909.21 CCD22609.1 - 1.8e-120 402.3 22.4 2.1e-120 402.1 22.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 CCD22609.1 - 0.0082 16.1 0.2 0.0082 16.1 0.2 3.9 4 0 0 4 4 4 1 Bacteriophage P21 holin S ABC2_membrane_2 PF12679.7 CCD22609.1 - 3.2 7.0 11.1 0.56 9.4 4.6 2.4 2 1 0 2 2 2 0 ABC-2 family transporter protein WD40 PF00400.32 CCD22610.1 - 1.1e-14 54.6 2.3 9.5e-05 23.1 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_like PF17005.5 CCD22610.1 - 8.8e-05 22.0 0.4 1.1 8.5 0.0 3.6 4 0 0 4 4 4 2 WD40-like domain Mcl1_mid PF12341.8 CCD22611.1 - 3.2e-86 289.3 0.0 5.6e-86 288.5 0.0 1.4 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 CCD22611.1 - 5.9e-06 26.5 0.0 0.21 11.9 0.0 3.8 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Utp8 PF10395.9 CCD22611.1 - 0.0015 17.1 0.1 0.0029 16.2 0.1 1.4 1 0 0 1 1 1 1 Utp8 family KTSC PF13619.6 CCD22611.1 - 0.093 12.6 0.2 0.34 10.7 0.1 2.0 2 0 0 2 2 2 0 KTSC domain HPS3_N PF14761.6 CCD22611.1 - 0.12 11.9 0.0 0.48 9.9 0.0 2.0 1 1 0 1 1 1 0 Hermansky-Pudlak syndrome 3 IL4Ra_N PF09238.10 CCD22612.1 - 0.11 12.8 0.0 22 5.4 0.0 2.3 2 0 0 2 2 2 0 Interleukin-4 receptor alpha chain, N-terminal Med26 PF08711.11 CCD22613.1 - 1.8e-13 50.2 0.3 2.3e-12 46.8 0.0 2.7 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Phasin PF05597.11 CCD22613.1 - 0.024 14.6 0.8 0.11 12.5 0.8 2.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Ribosom_S12_S23 PF00164.25 CCD22614.1 - 7.5e-51 170.5 0.3 9.6e-51 170.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acetyltransf_1 PF00583.25 CCD22615.1 - 2.5e-09 37.4 0.0 3.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CCD22615.1 - 6.3e-06 26.5 0.0 9.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCD22615.1 - 4.3e-05 23.4 0.0 8.5e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CCD22615.1 - 8.5e-05 22.5 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HasA PF06438.12 CCD22615.1 - 0.022 14.4 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 Heme-binding protein A (HasA) Mito_carr PF00153.27 CCD22616.1 - 2.6e-54 181.1 6.0 1.3e-18 66.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldo_ket_red PF00248.21 CCD22617.1 - 2.7e-46 158.1 0.0 3.4e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LETM1 PF07766.13 CCD22618.1 - 7.7e-94 314.0 4.4 7.7e-94 314.0 4.4 1.6 2 0 0 2 2 2 1 LETM1-like protein Pinin_SDK_memA PF04696.13 CCD22618.1 - 4.9 7.2 12.6 0.72 9.9 7.7 1.9 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region SH2_2 PF14633.6 CCD22619.1 - 8e-68 228.1 2.7 8e-68 228.1 2.7 2.2 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 CCD22619.1 - 5.7e-64 214.4 0.1 1.7e-63 212.9 0.1 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 CCD22619.1 - 7.1e-45 151.6 1.5 7.3e-44 148.4 0.2 3.2 3 0 0 3 3 3 1 Helix-hairpin-helix motif HTH_44 PF14641.6 CCD22619.1 - 1.6e-34 118.8 3.7 2.2e-34 118.4 1.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 CCD22619.1 - 4.8e-21 75.2 21.6 4.8e-21 75.2 21.6 6.2 4 1 2 6 6 6 1 Acidic N-terminal SPT6 SH2 PF00017.24 CCD22619.1 - 2e-12 47.0 0.1 7e-12 45.3 0.1 2.1 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 CCD22619.1 - 6.6e-05 23.7 1.4 0.0007 20.5 0.2 3.7 2 0 0 2 2 2 1 HHH domain Tex_YqgF PF16921.5 CCD22619.1 - 0.0094 16.4 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 1 Tex protein YqgF-like domain Ctr PF04145.15 CCD22620.1 - 1.9e-19 70.8 2.3 1.9e-19 70.8 2.3 1.8 2 0 0 2 2 2 1 Ctr copper transporter family Peptidase_M16 PF00675.20 CCD22621.1 - 2.7e-33 115.1 0.0 7.6e-33 113.6 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CCD22621.1 - 3.1e-13 50.1 0.3 2.9e-05 24.2 0.0 4.6 4 1 0 4 4 4 3 Peptidase M16 inactive domain Peptidase_M16_M PF16187.5 CCD22621.1 - 9.9e-12 44.7 0.3 2e-11 43.7 0.3 1.6 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Cyclin_N PF00134.23 CCD22622.1 - 7.3e-40 135.6 0.1 4.6e-39 133.1 0.1 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCD22622.1 - 2.2e-32 111.7 0.0 7.1e-32 110.0 0.0 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 CCD22623.1 - 2.2e-41 140.6 0.6 1.9e-40 137.5 0.2 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCD22623.1 - 5.9e-19 68.3 1.5 2.3e-18 66.4 0.2 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain IF-2B PF01008.17 CCD22624.1 - 6.2e-84 281.5 0.1 7.6e-84 281.2 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Fmp27_WPPW PF10359.9 CCD22625.1 - 4.8e-138 461.0 4.1 9e-138 460.1 4.1 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 CCD22625.1 - 5.5e-98 328.9 0.4 5.5e-98 328.9 0.4 3.0 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 CCD22625.1 - 6.6e-47 159.5 0.3 2.3e-46 157.7 0.3 2.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CCD22625.1 - 8.3e-42 142.7 1.5 4e-41 140.5 1.5 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 CCD22625.1 - 1.1e-20 74.3 2.5 2.5e-20 73.1 0.1 3.1 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain FapA PF03961.13 CCD22625.1 - 0.082 11.5 2.8 0.21 10.1 2.8 1.7 1 0 0 1 1 1 0 Flagellar Assembly Protein A RRG8 PF17068.5 CCD22626.1 - 4e-55 187.2 8.2 1.2e-46 159.3 2.9 2.0 1 1 0 2 2 2 2 Required for respiratory growth protein 8 mitochondrial CPSase_L_D2 PF02786.17 CCD22626.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain TRAM_LAG1_CLN8 PF03798.16 CCD22628.1 - 2.1e-32 112.5 18.1 2.1e-32 112.5 18.1 1.6 2 0 0 2 2 2 1 TLC domain Orf78 PF06024.12 CCD22628.1 - 0.69 10.2 0.0 0.69 10.2 0.0 2.9 4 0 0 4 4 4 0 Orf78 (ac78) CDP-OH_P_transf PF01066.21 CCD22629.1 - 3.5e-14 53.3 0.7 3.5e-14 53.3 0.7 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase tRNA-synt_1 PF00133.22 CCD22630.1 - 2.6e-237 788.9 0.1 4.1e-236 785.0 0.1 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CCD22630.1 - 1.5e-30 106.1 1.7 6.2e-30 104.2 1.7 2.1 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CCD22630.1 - 1.3e-14 53.7 0.4 1.2e-07 30.8 0.1 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CCD22630.1 - 3e-09 36.7 7.0 3.7e-07 29.8 0.0 3.7 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 CCD22630.1 - 0.015 15.5 7.2 0.015 15.5 7.2 3.2 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 CCD22630.1 - 0.21 10.9 9.1 0.97 8.7 0.0 3.6 4 1 0 4 4 4 0 tRNA synthetases class I (C) catalytic domain Lge1 PF11488.8 CCD22630.1 - 9.5 6.5 7.9 0.51 10.6 1.5 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 RRM_1 PF00076.22 CCD22631.1 - 1.3e-66 220.4 13.6 8.3e-17 60.8 0.1 6.4 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCD22631.1 - 5.5e-06 26.1 0.0 0.32 10.9 0.0 4.4 4 0 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CCD22631.1 - 1.1e-05 25.4 0.1 1.7 8.7 0.0 4.7 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CCD22631.1 - 4e-05 23.2 0.0 0.0053 16.3 0.0 3.5 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD22631.1 - 0.0027 17.8 0.4 5.1 7.3 0.0 4.6 5 0 0 5 5 5 1 RNA recognition motif DUF1699 PF08004.11 CCD22631.1 - 0.043 13.5 2.3 3.8 7.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) Limkain-b1 PF11608.8 CCD22631.1 - 0.096 12.8 1.8 55 3.9 0.0 4.3 4 0 0 4 4 4 0 Limkain b1 Pkinase PF00069.25 CCD22632.1 - 3.4e-53 180.7 0.1 7.4e-52 176.3 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22632.1 - 5.7e-26 91.3 0.2 1.2e-19 70.6 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CCD22632.1 - 0.00031 19.8 0.3 0.00045 19.3 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CCD22632.1 - 0.0027 17.7 0.0 0.056 13.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CCD22632.1 - 0.0065 15.8 0.1 0.022 14.1 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CCD22632.1 - 0.0085 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_A_bac PF01000.26 CCD22633.1 - 2.1e-28 98.9 0.0 3.8e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CCD22633.1 - 2e-21 75.2 0.0 2.7e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1746 PF08508.10 CCD22634.1 - 1.7e-06 28.4 3.1 0.0091 16.3 0.1 3.0 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1746) RPN7 PF10602.9 CCD22635.1 - 1.3e-51 174.7 3.2 1.3e-51 174.7 3.2 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 CCD22635.1 - 4e-15 56.2 0.1 1.2e-14 54.7 0.1 1.9 1 0 0 1 1 1 1 PCI domain DUF357 PF04010.13 CCD22635.1 - 0.034 14.2 0.5 0.14 12.3 0.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF357) TPR_8 PF13181.6 CCD22635.1 - 0.037 14.2 0.4 0.037 14.2 0.4 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-CCCH PF00642.24 CCD22636.1 - 4.4e-12 45.6 29.0 0.00072 19.4 0.5 5.6 4 2 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CCD22636.1 - 1.4e-10 40.9 29.2 6.8e-06 26.0 2.5 5.3 5 0 0 5 5 5 3 Zinc finger domain Torus PF16131.5 CCD22636.1 - 1e-07 32.6 20.8 0.0027 18.4 0.5 4.5 1 1 5 6 6 6 3 Torus domain zf-CCCH_3 PF15663.5 CCD22636.1 - 2.2e-07 31.0 12.4 6.5e-06 26.3 6.0 2.3 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 CCD22636.1 - 0.028 14.2 1.2 0.028 14.2 1.2 4.2 4 1 0 4 4 4 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CCD22636.1 - 5.7 7.6 31.0 0.63 10.6 1.1 5.6 5 1 0 5 5 5 0 RNA-binding, Nab2-type zinc finger Pkinase PF00069.25 CCD22637.1 - 2.3e-13 50.1 4.1 2.3e-13 50.1 4.1 2.1 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22637.1 - 5.6e-08 32.4 0.6 2.9e-07 30.1 0.6 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pil1 PF13805.6 CCD22638.1 - 2.5e-116 387.8 0.3 3.8e-116 387.2 0.3 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 Casc1_N PF15927.5 CCD22638.1 - 0.0029 17.3 0.1 0.0029 17.3 0.1 2.8 3 0 0 3 3 3 1 Cancer susceptibility candidate 1 N-terminus DUF739 PF05339.11 CCD22638.1 - 0.084 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF739) DUF4446 PF14584.6 CCD22638.1 - 1 9.4 4.4 9.4 6.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) CNDH2_C PF16858.5 CCD22638.1 - 3.7 7.3 13.3 0.92 9.3 7.4 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term COG4 PF08318.12 CCD22639.1 - 2.1e-87 293.3 8.8 5e-87 292.1 8.8 1.7 1 0 0 1 1 1 1 COG4 transport protein Forkhead PF00250.18 CCD22640.1 - 2e-25 88.9 0.1 7.7e-25 87.0 0.1 2.1 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 CCD22640.1 - 7e-13 48.7 1.0 2.3e-12 47.1 0.3 2.4 2 0 0 2 2 2 1 FHA domain Linker_histone PF00538.19 CCD22640.1 - 0.015 15.6 0.1 1.2 9.6 0.0 3.2 2 0 0 2 2 2 0 linker histone H1 and H5 family Proteasome PF00227.26 CCD22641.1 - 5e-48 163.1 0.1 6e-48 162.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_L5_C PF00673.21 CCD22642.1 - 1.6e-22 79.5 0.0 2.5e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CCD22642.1 - 5.4e-20 71.5 0.1 1.7e-19 69.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 CCD22642.1 - 0.0077 15.9 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain BCAS2 PF05700.11 CCD22643.1 - 7.9e-06 25.7 12.9 6.8e-05 22.7 12.9 2.2 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) L51_S25_CI-B8 PF05047.16 CCD22644.1 - 6e-13 48.5 0.4 1.2e-12 47.6 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF4149 PF13664.6 CCD22645.1 - 3.3e-21 75.5 0.6 3.3e-21 75.5 0.6 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) MAS20 PF02064.15 CCD22646.1 - 2e-35 121.7 0.7 2.8e-35 121.2 0.7 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor DUF4015 PF13200.6 CCD22646.1 - 0.054 12.5 0.1 0.065 12.3 0.1 1.1 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain DUF3818 PF12825.7 CCD22647.1 - 1e-124 416.0 14.4 1e-124 416.0 14.4 2.5 3 0 0 3 3 3 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 CCD22647.1 - 1.7e-38 131.6 1.8 1.7e-38 131.6 1.8 2.6 2 0 0 2 2 2 1 PX-associated PX PF00787.24 CCD22647.1 - 7.2e-10 38.8 8.6 1.5e-09 37.8 4.1 3.3 2 1 0 2 2 2 1 PX domain RNA_pol_3_Rpc31 PF11705.8 CCD22647.1 - 0.0072 16.6 13.1 0.0072 16.6 13.1 2.5 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 CCD22647.1 - 0.37 10.1 24.1 0.71 9.1 24.1 1.4 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.13 CCD22647.1 - 1.2 9.1 15.6 0.19 11.7 10.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RNaseH_like PF04308.12 CCD22647.1 - 5.8 6.8 6.4 0.57 10.1 1.1 2.0 2 0 0 2 2 2 0 Ribonuclease H-like Sec7 PF01369.20 CCD22648.1 - 2.5e-27 95.8 6.0 4.6e-27 94.9 3.7 2.5 2 1 1 3 3 3 1 Sec7 domain PHF5 PF03660.14 CCD22649.1 - 2.1e-51 172.5 14.9 2.3e-51 172.3 14.9 1.0 1 0 0 1 1 1 1 PHF5-like protein MMM1 PF10296.9 CCD22650.1 - 4.5e-08 32.5 0.1 4.5e-08 32.5 0.1 2.7 2 2 1 3 3 3 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 CCD22650.1 - 1.5e-06 28.6 0.0 1.5e-06 28.6 0.0 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 CCD22650.1 - 9.6e-06 26.1 4.5 1.2e-05 25.7 0.3 3.1 3 1 0 3 3 3 1 PH domain DIL PF01843.19 CCD22651.1 - 6.6e-17 61.7 3.4 5e-08 33.1 0.2 3.0 2 0 0 2 2 2 2 DIL domain Ank_2 PF12796.7 CCD22651.1 - 1.2e-05 25.8 0.1 2.7e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CCD22651.1 - 0.0017 18.6 0.3 0.019 15.3 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF3134 PF11332.8 CCD22651.1 - 0.011 16.1 0.1 0.011 16.1 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3134) Ank_4 PF13637.6 CCD22651.1 - 0.033 14.8 0.5 1.1 9.9 0.1 2.8 1 1 1 2 2 2 0 Ankyrin repeats (many copies) SHE3 PF17078.5 CCD22652.1 - 4.7e-47 160.6 41.5 6.8e-47 160.1 41.5 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 FPP PF05911.11 CCD22652.1 - 0.00073 17.9 19.5 0.001 17.4 19.5 1.3 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil BLOC1_2 PF10046.9 CCD22652.1 - 0.0014 18.8 8.1 0.0014 18.8 8.1 3.9 1 1 2 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Taxilin PF09728.9 CCD22652.1 - 0.015 14.5 26.7 0.3 10.2 4.0 2.4 1 1 0 2 2 2 0 Myosin-like coiled-coil protein DUF3584 PF12128.8 CCD22652.1 - 0.045 11.3 23.2 0.059 10.9 23.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) OmpH PF03938.14 CCD22652.1 - 0.079 13.3 24.7 0.23 11.8 10.3 2.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ABC_tran_CTD PF16326.5 CCD22652.1 - 0.082 13.2 16.7 0.15 12.4 5.6 3.4 2 1 1 3 3 3 0 ABC transporter C-terminal domain Laminin_II PF06009.12 CCD22652.1 - 0.083 12.9 24.3 0.03 14.3 7.3 3.4 1 1 2 3 3 3 0 Laminin Domain II DUF4407 PF14362.6 CCD22652.1 - 0.15 11.4 16.0 0.23 10.8 2.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HrpB7 PF09486.10 CCD22652.1 - 0.16 12.4 4.6 2.6 8.4 0.2 2.5 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) PIN_8 PF18476.1 CCD22652.1 - 0.21 11.4 20.7 0.056 13.3 13.8 2.5 1 1 1 2 2 2 0 PIN like domain FliJ PF02050.16 CCD22652.1 - 0.21 11.8 25.2 0.44 10.8 4.3 3.4 1 1 2 3 3 3 0 Flagellar FliJ protein Tup_N PF08581.10 CCD22652.1 - 0.25 11.7 27.2 0.2 12.0 11.5 4.2 1 1 2 3 3 3 0 Tup N-terminal Cob_adeno_trans PF01923.18 CCD22652.1 - 0.26 11.4 9.7 2.5 8.2 1.6 2.5 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF2935 PF11155.8 CCD22652.1 - 0.32 11.3 8.0 0.48 10.8 3.1 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) SKA2 PF16740.5 CCD22652.1 - 0.44 10.3 17.6 0.9 9.4 6.9 2.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF1664 PF07889.12 CCD22652.1 - 0.48 10.5 19.9 0.97 9.5 6.6 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 CCD22652.1 - 0.49 9.2 31.3 0.074 11.9 16.6 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein TEX12 PF15219.6 CCD22652.1 - 0.54 10.6 7.5 0.22 11.9 2.2 2.5 1 1 1 2 2 2 0 Testis-expressed 12 APG6_N PF17675.1 CCD22652.1 - 0.57 10.7 29.9 0.099 13.2 17.1 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region T3SSipB PF16535.5 CCD22652.1 - 0.67 10.4 14.4 0.14 12.6 4.3 2.3 1 1 1 2 2 2 0 Type III cell invasion protein SipB BRE1 PF08647.11 CCD22652.1 - 1.1 9.4 28.9 0.029 14.5 13.3 3.2 2 2 0 2 2 2 0 BRE1 E3 ubiquitin ligase Tho2 PF11262.8 CCD22652.1 - 1.2 8.2 23.5 1.7 7.8 7.9 2.4 1 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF349 PF03993.12 CCD22652.1 - 1.8 8.9 6.5 0.62 10.4 0.9 2.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF3450 PF11932.8 CCD22652.1 - 1.8 7.8 27.9 0.23 10.7 6.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) KASH_CCD PF14662.6 CCD22652.1 - 1.9 8.3 30.9 25 4.6 29.9 2.2 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4200 PF13863.6 CCD22652.1 - 2.1 8.8 23.4 0.18 12.2 9.7 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF4164 PF13747.6 CCD22652.1 - 2.5 8.4 10.8 7.3 6.9 2.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) FapA PF03961.13 CCD22652.1 - 2.5 6.6 27.3 0.17 10.4 10.2 2.5 1 1 1 2 2 2 0 Flagellar Assembly Protein A Jnk-SapK_ap_N PF09744.9 CCD22652.1 - 3 8.0 29.5 6 7.1 3.8 2.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ISG65-75 PF11727.8 CCD22652.1 - 3.5 6.8 14.4 1.1 8.4 5.4 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein JIP_LZII PF16471.5 CCD22652.1 - 5.9 7.1 23.6 6.8 6.9 7.2 3.6 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II DUF724 PF05266.14 CCD22652.1 - 6.1 6.6 19.3 0.47 10.3 10.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF489 PF04356.12 CCD22652.1 - 6.8 6.6 18.0 2.5 8.1 6.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF489) WXG100 PF06013.12 CCD22652.1 - 8.6 6.7 13.8 0.63 10.3 2.8 4.0 1 1 2 3 3 3 0 Proteins of 100 residues with WXG NPV_P10 PF05531.12 CCD22652.1 - 8.8 6.9 23.3 4e+02 1.6 1.7 4.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-H PF05837.12 CCD22652.1 - 9.2 6.7 26.7 4.8 7.6 0.8 3.7 1 1 1 2 2 1 0 Centromere protein H (CENP-H) WD40 PF00400.32 CCD22653.1 - 3.4e-05 24.5 0.1 0.0077 17.1 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Ras PF00071.22 CCD22654.1 - 3.1e-05 23.6 0.0 0.21 11.2 0.0 2.3 2 0 0 2 2 2 2 Ras family AAA_28 PF13521.6 CCD22654.1 - 0.034 14.4 0.0 0.061 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 CCD22654.1 - 0.1 12.8 0.0 0.35 11.1 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RVT_3 PF13456.6 CCD22655.1 - 0.45 10.3 7.4 3.1 7.6 0.2 2.9 3 0 0 3 3 3 0 Reverse transcriptase-like Glyco_transf_20 PF00982.21 CCD22656.1 - 4.2e-205 681.9 0.0 4.8e-205 681.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 CCD22656.1 - 0.00017 21.2 1.2 0.0028 17.2 0.1 2.8 3 1 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 CCD22656.1 - 0.15 11.7 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain DIM1 PF02966.16 CCD22657.1 - 3.7e-67 224.2 0.5 4.2e-67 224.0 0.5 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CCD22657.1 - 1.8e-05 24.6 0.1 2.5e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin DUF3192 PF11399.8 CCD22657.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) GTP_EFTU PF00009.27 CCD22658.1 - 4.4e-54 183.0 0.0 6.4e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CCD22658.1 - 5.2e-40 136.2 0.0 1.2e-39 135.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CCD22658.1 - 3.1e-14 53.1 1.8 3.1e-14 53.1 1.8 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCD22658.1 - 0.00044 20.3 0.1 0.011 15.8 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CCD22658.1 - 1.2 9.0 7.2 0.062 13.2 0.9 2.1 3 0 0 3 3 3 0 Elongation factor Tu domain 4 MACPF PF01823.19 CCD22659.1 - 0.017 15.2 3.9 0.071 13.2 0.0 2.3 2 0 0 2 2 2 0 MAC/Perforin domain CCDC74_C PF14917.6 CCD22659.1 - 0.025 15.1 1.5 0.046 14.2 1.5 1.4 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal WXG100 PF06013.12 CCD22659.1 - 0.027 14.7 1.3 5.6 7.3 0.2 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF948 PF06103.11 CCD22659.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) RasGAP_C PF03836.15 CCD22659.1 - 0.058 13.5 5.1 0.04 14.1 2.8 1.8 2 0 0 2 2 2 0 RasGAP C-terminus ABC_tran_CTD PF16326.5 CCD22659.1 - 0.16 12.3 5.9 0.096 13.0 1.2 2.7 2 1 1 3 3 3 0 ABC transporter C-terminal domain Exonuc_VII_L PF02601.15 CCD22659.1 - 0.28 10.7 2.9 0.4 10.2 0.4 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 CCD22659.1 - 0.89 9.7 8.1 15 5.8 0.1 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Fzo_mitofusin PF04799.13 CCD22659.1 - 3 7.4 7.2 1.7 8.2 3.5 2.3 2 1 1 3 3 3 0 fzo-like conserved region Occludin_ELL PF07303.13 CCD22659.1 - 3.8 8.3 7.6 9.6 7.0 3.7 2.5 2 1 0 2 2 2 0 Occludin homology domain Tup_N PF08581.10 CCD22659.1 - 4.7 7.6 6.9 1.9 8.9 1.1 2.6 2 1 0 3 3 3 0 Tup N-terminal Opy2 PF09463.10 CCD22660.1 - 2e-09 37.6 18.1 3e-09 37.0 18.1 1.3 1 0 0 1 1 1 1 Opy2 protein Herpes_gE PF02480.16 CCD22660.1 - 0.0051 15.6 0.0 0.0074 15.1 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Amnionless PF14828.6 CCD22660.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Amnionless FAM176 PF14851.6 CCD22660.1 - 0.021 14.5 3.2 0.026 14.2 0.0 2.2 2 0 0 2 2 2 0 FAM176 family MAP17 PF15807.5 CCD22660.1 - 0.043 14.0 1.9 0.26 11.5 0.0 2.5 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DGF-1_C PF11040.8 CCD22660.1 - 0.084 12.9 1.1 1.9 8.5 1.0 2.7 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Syndecan PF01034.20 CCD22660.1 - 0.13 12.2 2.9 0.26 11.2 2.9 1.4 1 0 0 1 1 1 0 Syndecan domain Transketolase_N PF00456.21 CCD22661.1 - 8.3e-162 537.8 0.0 2.2e-161 536.4 0.0 1.6 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CCD22661.1 - 1.1e-47 162.0 0.0 1.8e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CCD22661.1 - 7.1e-13 48.5 0.0 2.2e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 CCD22661.1 - 0.00032 19.7 0.0 0.00057 18.9 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CCD22661.1 - 0.0013 18.0 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase LMWPc PF01451.21 CCD22662.1 - 5.1e-41 140.4 0.0 5.8e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Not3 PF04065.15 CCD22663.1 - 4.7e-65 219.3 42.4 6.6e-64 215.5 31.0 3.4 2 1 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CCD22663.1 - 2.3e-38 131.2 7.0 2.3e-38 131.2 7.0 2.6 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Plasmid_RAQPRD PF09686.10 CCD22663.1 - 0.039 14.2 4.9 0.06 13.6 1.0 3.1 3 1 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) MCD PF05292.11 CCD22663.1 - 0.94 9.0 8.2 0.82 9.2 1.8 2.4 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain PCRF PF03462.18 CCD22663.1 - 4 7.3 22.7 0.57 10.0 1.1 3.6 3 1 0 3 3 3 0 PCRF domain TPR_1 PF00515.28 CCD22665.1 - 9.4e-48 158.2 21.4 2.5e-07 30.2 0.0 10.9 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 CCD22665.1 - 1e-40 134.5 28.3 0.00014 21.7 0.0 10.8 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 CCD22665.1 - 1.3e-27 93.7 18.3 0.026 14.7 0.0 10.5 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_17 PF13431.6 CCD22665.1 - 1.9e-27 93.6 23.1 4.2e-05 23.6 0.2 11.8 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.6 CCD22665.1 - 1e-17 63.5 33.3 5.1e-05 22.9 0.0 9.9 5 2 6 11 11 10 5 TPR repeat TPR_14 PF13428.6 CCD22665.1 - 7.2e-17 60.7 34.7 0.0067 17.2 0.4 10.8 4 2 7 11 11 10 7 Tetratricopeptide repeat TPR_7 PF13176.6 CCD22665.1 - 1e-15 56.5 23.0 0.00073 19.4 0.7 9.3 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 CCD22665.1 - 2.1e-15 57.0 32.4 0.00042 20.9 0.9 7.5 5 3 2 7 7 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 CCD22665.1 - 6.2e-12 45.5 33.0 0.0018 18.4 0.0 7.5 4 1 4 8 8 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 CCD22665.1 - 4.6e-11 43.1 54.1 1.4e-05 25.5 0.4 9.0 6 3 2 8 8 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 CCD22665.1 - 1.1e-10 41.7 52.9 0.00024 21.3 0.4 9.8 5 2 6 11 11 10 8 Tetratricopeptide repeat TPR_6 PF13174.6 CCD22665.1 - 4.4e-08 33.3 39.7 0.45 11.3 0.0 11.1 11 1 0 11 11 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD22665.1 - 4.8e-06 26.7 25.5 0.0009 19.4 0.1 4.6 5 1 0 5 5 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CCD22665.1 - 0.01 15.7 23.1 0.36 10.8 0.8 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.6 CCD22665.1 - 0.023 13.9 0.1 0.023 13.9 0.1 6.2 3 1 1 6 6 4 0 Tetratricopeptide repeat Med1 PF10744.9 CCD22666.1 - 1.4e-26 93.5 8.1 1.1e-25 90.6 4.5 2.9 1 1 1 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 Novirhabdo_Nv PF05554.11 CCD22666.1 - 0.26 11.1 2.7 0.37 10.5 1.1 2.0 2 0 0 2 2 2 0 Viral hemorrhagic septicemia virus non-virion protein Hist_deacetyl PF00850.19 CCD22667.1 - 2.8e-76 256.9 0.0 4e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain EF-hand_1 PF00036.32 CCD22668.1 - 4.3e-18 63.4 3.9 8.2e-09 34.4 0.1 3.5 3 1 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 CCD22668.1 - 1.1e-15 57.8 1.1 4.2e-07 30.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCD22668.1 - 5e-14 51.0 3.0 2.7e-08 33.1 0.1 3.5 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CCD22668.1 - 5.4e-14 51.8 2.9 7.4e-08 32.1 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CCD22668.1 - 2.1e-09 36.4 1.1 8.6e-08 31.3 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 CCD22668.1 - 6.7e-05 23.1 0.1 0.14 12.5 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CCD22668.1 - 0.0036 17.6 0.5 2.4 8.5 0.1 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region RNA_pol_Rpb4 PF03874.16 CCD22668.1 - 0.0081 16.5 0.4 0.15 12.4 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase Rpb4 EF-hand_11 PF08976.11 CCD22668.1 - 0.059 14.2 0.0 9 7.2 0.0 2.0 1 1 1 2 2 2 0 EF-hand domain DUF533 PF04391.12 CCD22668.1 - 0.12 11.9 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) AIM3 PF17096.5 CCD22669.1 - 6.3e-19 68.7 3.5 6.3e-19 68.7 3.5 5.0 4 1 0 4 4 4 1 Altered inheritance of mitochondria protein 3 DUF3824 PF12868.7 CCD22669.1 - 0.009 16.7 17.0 0.009 16.7 17.0 5.9 1 1 2 4 4 4 1 Domain of unknwon function (DUF3824) Fe-S_biosyn PF01521.20 CCD22670.1 - 1.8e-13 50.6 0.4 1.1e-06 28.8 0.2 2.2 1 1 1 2 2 2 2 Iron-sulphur cluster biosynthesis ThiF PF00899.21 CCD22671.1 - 2.8e-55 187.3 0.0 3.3e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CCD22671.1 - 0.0045 17.0 0.1 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase PglD_N PF17836.1 CCD22671.1 - 0.035 14.7 0.6 0.18 12.4 0.2 2.4 2 1 0 2 2 2 0 PglD N-terminal domain Sacchrp_dh_NADP PF03435.18 CCD22671.1 - 0.074 13.3 0.0 0.38 11.0 0.0 2.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 CCD22671.1 - 0.085 13.4 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Tubulin_2 PF13809.6 CCD22671.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Pho88 PF10032.9 CCD22672.1 - 4e-78 260.8 0.2 4.5e-78 260.7 0.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) ArsP_1 PF03773.13 CCD22672.1 - 0.086 12.0 0.4 0.11 11.6 0.4 1.1 1 0 0 1 1 1 0 Predicted permease HMG_box PF00505.19 CCD22673.1 - 7.6e-16 58.3 4.9 7.6e-16 58.3 4.9 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCD22673.1 - 4.3e-09 36.8 1.7 8.6e-09 35.9 1.7 1.5 1 0 0 1 1 1 1 HMG-box domain Vac_ImportDeg PF09783.9 CCD22674.1 - 5.8e-47 159.5 1.9 9.2e-47 158.9 1.9 1.3 1 0 0 1 1 1 1 Vacuolar import and degradation protein UPF0139 PF03669.13 CCD22675.1 - 4.3e-05 23.3 0.3 0.00013 21.8 0.3 1.8 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0139) dCMP_cyt_deam_1 PF00383.23 CCD22676.1 - 7.6e-22 77.1 0.0 9.6e-22 76.8 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCD22676.1 - 3.5e-19 68.9 0.0 4.6e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 CCD22676.1 - 0.00094 19.3 0.0 0.0022 18.1 0.0 1.6 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 CCD22676.1 - 0.0017 18.4 0.0 0.043 13.9 0.0 2.0 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 Bd3614-deam PF14439.6 CCD22676.1 - 0.0029 17.7 0.2 0.0057 16.7 0.1 1.5 1 1 1 2 2 2 1 Bd3614-like deaminase APOBEC2 PF18772.1 CCD22676.1 - 0.011 15.8 0.0 0.059 13.4 0.0 1.8 2 0 0 2 2 2 0 APOBEC2 APOBEC4 PF18775.1 CCD22676.1 - 0.02 15.0 0.6 6.1 7.1 0.1 2.2 1 1 0 2 2 2 0 APOBEC4 APOBEC_N PF08210.11 CCD22676.1 - 0.059 13.3 0.1 0.24 11.3 0.1 1.8 1 1 0 1 1 1 0 APOBEC-like N-terminal domain NAD2 PF18782.1 CCD22676.1 - 0.095 12.8 0.0 0.21 11.7 0.0 1.5 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 APOBEC4_like PF18774.1 CCD22676.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.5 1 1 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase DnaJ PF00226.31 CCD22677.1 - 4.1e-10 39.6 8.3 2.9e-09 36.9 5.7 2.9 2 1 0 2 2 2 1 DnaJ domain CM_2 PF01817.21 CCD22678.1 - 0.078 13.3 0.0 0.3 11.5 0.0 1.9 1 1 0 1 1 1 0 Chorismate mutase type II Mito_carr PF00153.27 CCD22679.1 - 1.3e-57 191.7 2.0 2e-20 72.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SIP1 PF04938.12 CCD22680.1 - 4.1e-06 26.7 0.5 5e-05 23.1 0.5 2.3 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Spectrin PF00435.21 CCD22680.1 - 0.056 13.9 0.9 0.098 13.2 0.9 1.5 1 0 0 1 1 1 0 Spectrin repeat DUF5598 PF18127.1 CCD22680.1 - 0.084 13.3 0.6 0.2 12.1 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5598) Tfb4 PF03850.14 CCD22681.1 - 3.8e-108 361.2 0.2 4.4e-108 361.0 0.2 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Rad50_zn_hook PF04423.14 CCD22681.1 - 0.012 15.4 0.2 0.071 13.0 0.2 2.3 1 0 0 1 1 1 0 Rad50 zinc hook motif Cucumopine_C PF18631.1 CCD22681.1 - 0.029 14.3 0.1 3 7.8 0.0 2.9 3 0 0 3 3 3 0 Cucumopine synthase C-terminal helical bundle domain Sec8_exocyst PF04048.14 CCD22682.1 - 2.4e-45 153.9 6.0 2.4e-45 153.9 6.0 4.1 4 0 0 4 4 4 1 Sec8 exocyst complex component specific domain Exonuc_VII_L PF02601.15 CCD22682.1 - 0.43 10.1 8.0 0.16 11.5 4.3 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Pkinase PF00069.25 CCD22683.1 - 1.7e-56 191.5 1.5 4.5e-56 190.1 1.5 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22683.1 - 2.6e-27 95.7 0.1 1.8e-22 79.9 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CCD22683.1 - 0.00012 21.2 0.3 0.0002 20.4 0.3 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CCD22683.1 - 0.047 13.0 0.1 0.075 12.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCD22683.1 - 0.11 11.8 0.1 0.41 9.9 0.1 1.9 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 CCD22683.1 - 0.17 11.7 0.1 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HMG_box PF00505.19 CCD22684.1 - 8.5e-26 90.2 0.6 1.2e-25 89.7 0.6 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCD22684.1 - 2.7e-17 63.1 0.7 2.7e-17 63.1 0.7 1.3 2 0 0 2 2 2 1 HMG-box domain CHDNT PF08073.12 CCD22684.1 - 7.6e-05 22.6 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain Ccdc124 PF06244.12 CCD22684.1 - 0.0024 18.4 0.5 0.0093 16.5 0.0 1.9 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 CCD22684.1 - 0.013 15.4 2.3 0.013 15.4 2.3 1.5 1 1 0 1 1 1 0 HMG (high mobility group) box 5 YABBY PF04690.13 CCD22684.1 - 0.072 13.7 0.5 0.072 13.7 0.5 1.5 1 1 0 1 1 1 0 YABBY protein Acetyltransf_1 PF00583.25 CCD22685.1 - 9.9e-16 58.0 0.0 1.2e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CCD22685.1 - 1.3e-11 44.7 0.0 1.7e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CCD22685.1 - 3.3e-10 40.0 0.0 4.5e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCD22685.1 - 6.2e-06 26.1 0.1 9.8e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CCD22685.1 - 0.00015 21.9 0.0 0.00038 20.5 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CCD22685.1 - 0.0014 18.3 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CCD22685.1 - 0.003 18.2 0.0 0.0035 18.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CCD22685.1 - 0.0068 16.5 0.0 0.018 15.2 0.0 1.6 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 CCD22685.1 - 0.011 15.2 0.1 0.044 13.3 0.1 1.8 1 1 0 1 1 1 0 Putative acetyl-transferase Ribonuc_2-5A PF06479.12 CCD22685.1 - 0.026 14.7 0.2 0.048 13.9 0.2 1.4 1 0 0 1 1 1 0 Ribonuclease 2-5A ATG11 PF10377.9 CCD22686.1 - 1.5e-41 141.5 0.0 1.5e-41 141.5 0.0 3.5 4 0 0 4 4 4 1 Autophagy-related protein 11 Pox_A_type_inc PF04508.12 CCD22686.1 - 5.5 7.0 6.0 19 5.3 0.0 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat tRNA-synt_2d PF01409.20 CCD22687.1 - 3.1e-43 148.0 0.1 2.5e-25 89.4 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 CCD22687.1 - 1.2e-25 89.8 0.7 4.2e-25 88.0 0.1 2.2 2 1 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Tweety PF04906.13 CCD22687.1 - 0.96 8.0 3.6 0.23 10.1 0.1 1.6 2 0 0 2 2 2 0 Tweety Ribosomal_L16 PF00252.18 CCD22688.1 - 5.3e-36 123.5 0.0 7.9e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DNA_pol3_delta2 PF13177.6 CCD22689.1 - 1.2e-09 38.1 1.2 5.3e-09 36.1 0.3 2.3 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 CCD22689.1 - 1.8e-05 25.2 0.3 8.3e-05 23.0 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CCD22689.1 - 0.002 18.1 0.1 0.0042 17.0 0.1 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 CCD22689.1 - 0.0037 17.0 0.3 0.024 14.4 0.3 2.1 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 CCD22689.1 - 0.0075 16.7 0.0 0.022 15.2 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain Adaptin_N PF01602.20 CCD22690.1 - 1.7e-109 366.8 23.1 2.1e-109 366.5 23.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 CCD22690.1 - 2e-07 31.2 0.0 5.5e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain ATP-synt_8 PF00895.20 CCD22690.1 - 0.074 13.5 2.6 3.3 8.2 0.5 3.4 2 0 0 2 2 2 0 ATP synthase protein 8 Anoctamin PF04547.12 CCD22691.1 - 5.2e-34 117.9 27.9 5.2e-34 117.9 27.9 2.7 2 2 0 2 2 2 1 Calcium-activated chloride channel Pol_alpha_B_N PF08418.10 CCD22692.1 - 7e-68 229.2 9.3 1.1e-67 228.7 9.3 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 CCD22692.1 - 1.7e-50 171.3 1.3 2.8e-50 170.6 1.3 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CCD22692.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain CLASP_N PF12348.8 CCD22693.1 - 2.6e-51 174.4 8.8 2.6e-51 174.4 8.8 4.6 5 0 0 5 5 5 3 CLASP N terminal GTP_cyclohydro2 PF00925.20 CCD22694.1 - 2.6e-54 183.2 0.0 3.9e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II KH_1 PF00013.29 CCD22695.1 - 7.3e-28 96.2 10.7 6.5e-11 41.9 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CCD22695.1 - 7.2e-05 22.5 13.1 0.0062 16.3 0.5 3.5 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 CCD22695.1 - 0.0004 20.2 5.2 0.77 9.7 0.7 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 CCD22695.1 - 0.054 13.6 12.6 0.69 10.0 0.3 4.0 4 0 0 4 4 4 0 NusA-like KH domain Msap1 PF17077.5 CCD22696.1 - 5.4e-19 68.5 44.0 7e-14 51.7 28.6 3.4 1 1 1 2 2 2 2 Mitotic spindle associated protein SHE1 B-block_TFIIIC PF04182.12 CCD22696.1 - 0.16 12.1 3.0 14 5.9 0.1 3.0 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Mito_carr PF00153.27 CCD22697.1 - 1.4e-69 230.1 6.2 4.8e-25 87.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rep_1 PF01446.17 CCD22698.1 - 0.00047 19.7 0.1 0.00077 19.0 0.1 1.3 1 0 0 1 1 1 1 Replication protein zinc_ribbon_15 PF17032.5 CCD22698.1 - 0.006 17.3 0.1 0.01 16.5 0.1 1.4 1 0 0 1 1 1 1 zinc-ribbon family Zn_Tnp_IS1595 PF12760.7 CCD22698.1 - 0.0092 15.9 2.9 0.69 9.9 0.2 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 CCD22698.1 - 0.037 13.4 3.0 4.5 6.8 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-TFIIB PF13453.6 CCD22698.1 - 0.051 12.9 0.1 0.94 8.9 0.0 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger RecR PF02132.15 CCD22698.1 - 0.061 12.9 2.5 0.46 10.1 2.5 2.1 1 1 0 1 1 1 0 RecR protein Zn_Tnp_IS1 PF03811.13 CCD22698.1 - 0.2 11.4 2.0 6.4 6.6 0.3 2.2 2 0 0 2 2 2 0 InsA N-terminal domain TF_Zn_Ribbon PF08271.12 CCD22698.1 - 0.3 10.7 3.7 3.3 7.3 0.4 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding zf-LITAF-like PF10601.9 CCD22698.1 - 3.5 8.0 7.6 8 6.8 1.7 2.4 1 1 0 2 2 2 0 LITAF-like zinc ribbon domain DUF2423 PF10338.9 CCD22701.1 - 1.3e-17 63.8 6.5 1.3e-17 63.8 6.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Ribosomal_L19e PF01280.20 CCD22702.1 - 1.8e-58 196.7 9.4 1.8e-58 196.7 9.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e TilS PF09179.11 CCD22702.1 - 0.048 14.2 4.5 25 5.5 6.5 3.1 2 1 0 2 2 2 0 TilS substrate binding domain TEA PF01285.18 CCD22703.1 - 8.4e-26 89.8 0.6 1.7e-25 88.9 0.6 1.5 1 0 0 1 1 1 1 TEA/ATTS domain GP79 PF17463.2 CCD22703.1 - 0.044 13.8 0.0 0.61 10.1 0.0 2.4 2 0 0 2 2 2 0 Gene product 79 MCM6_C PF18263.1 CCD22703.1 - 0.11 12.8 0.3 0.18 12.1 0.3 1.3 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain UQ_con PF00179.26 CCD22704.1 - 5.1e-52 175.2 0.0 5.7e-52 175.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CCD22704.1 - 0.0011 19.3 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CCD22704.1 - 0.003 17.2 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CCD22704.1 - 0.0097 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 UEV domain Yos9_DD PF17880.1 CCD22706.1 - 3.7e-45 153.2 0.0 8.1e-45 152.1 0.0 1.6 1 0 0 1 1 1 1 Yos9 dimerzation domain PRKCSH PF07915.13 CCD22706.1 - 7.6e-10 39.7 0.5 7.6e-10 39.7 0.5 3.5 4 0 0 4 4 4 1 Glucosidase II beta subunit-like protein Recep_L_domain PF01030.24 CCD22707.1 - 8.3e-10 38.8 8.3 0.0089 16.1 0.0 5.2 1 1 4 5 5 5 4 Receptor L domain LRR_9 PF14580.6 CCD22707.1 - 0.00027 20.5 0.7 0.004 16.7 0.4 2.3 1 1 1 2 2 2 1 Leucine-rich repeat UQ_con PF00179.26 CCD22708.1 - 9.1e-45 151.8 0.0 1.4e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCD22708.1 - 0.03 14.0 0.0 0.12 12.1 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B Dfp1_Him1_M PF08630.10 CCD22709.1 - 2e-40 137.9 0.0 2e-40 137.9 0.0 2.4 3 0 0 3 3 3 1 Dfp1/Him1, central region zf-DBF PF07535.12 CCD22709.1 - 2.5e-19 69.1 3.4 5.6e-19 68.0 3.4 1.6 1 0 0 1 1 1 1 DBF zinc finger HHH_8 PF14716.6 CCD22709.1 - 0.021 15.2 0.0 0.086 13.2 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix domain His_Phos_1 PF00300.22 CCD22710.1 - 6.9e-25 87.9 0.0 1.6e-14 54.0 0.0 3.1 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) TIM PF00121.18 CCD22711.1 - 2.7e-90 302.0 0.1 3e-90 301.8 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Alg14 PF08660.11 CCD22712.1 - 2.8e-49 167.4 0.1 3.6e-49 167.1 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like HSP20 PF00011.21 CCD22714.1 - 1.1e-21 76.9 1.4 1.6e-21 76.3 1.4 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CCD22714.1 - 4.2e-06 26.2 0.0 6.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Pih1_fungal_CS PF18482.1 CCD22714.1 - 0.0043 17.5 1.2 0.015 15.8 0.4 2.3 2 1 0 2 2 2 1 Fungal Pih1 CS domain YolD PF08863.10 CCD22714.1 - 0.12 12.4 0.2 0.12 12.4 0.2 2.1 3 0 0 3 3 3 0 YolD-like protein bVLRF1 PF18826.1 CCD22715.1 - 1.1e-57 194.1 0.3 2.5e-57 192.9 0.3 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 CCD22715.1 - 0.00011 22.4 0.1 0.0007 19.8 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCD22715.1 - 0.00099 19.7 0.3 0.0031 18.1 0.3 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CCD22715.1 - 0.0063 16.9 0.1 0.21 12.2 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 CCD22715.1 - 0.011 16.3 0.0 0.033 14.8 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 CCD22715.1 - 0.016 15.7 0.2 0.04 14.4 0.2 1.7 1 0 0 1 1 1 0 Ankyrin repeat zf-met PF12874.7 CCD22715.1 - 0.021 15.2 0.7 0.048 14.1 0.7 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CCD22715.1 - 0.28 11.7 2.2 0.69 10.5 2.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 CCD22715.1 - 0.36 11.5 2.8 0.65 10.7 0.1 2.9 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats URO-D PF01208.17 CCD22716.1 - 1.9e-126 421.9 0.0 2.1e-126 421.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) AA_permease PF00324.21 CCD22717.1 - 1.6e-133 445.8 35.5 2e-133 445.5 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD22717.1 - 2.1e-33 115.8 33.5 2.8e-33 115.4 33.5 1.1 1 0 0 1 1 1 1 Amino acid permease TFIIS_C PF01096.18 CCD22718.1 - 1.3e-21 76.1 2.2 1.3e-21 76.1 2.2 2.9 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CCD22718.1 - 4.5e-17 61.6 1.6 1.5e-16 60.0 0.3 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 CCD22718.1 - 0.00094 19.1 4.7 0.34 10.9 0.6 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 CCD22718.1 - 0.067 13.2 0.4 0.067 13.2 0.4 3.0 3 0 0 3 3 3 0 PhnA Zinc-Ribbon IBR PF01485.21 CCD22718.1 - 0.15 12.3 9.8 0.63 10.3 0.2 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain DZR PF12773.7 CCD22718.1 - 0.55 10.3 6.4 0.76 9.8 0.3 2.6 2 1 0 2 2 2 0 Double zinc ribbon Coprogen_oxidas PF01218.18 CCD22719.1 - 2.5e-130 433.5 0.0 2.8e-130 433.3 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase zf-C2H2 PF00096.26 CCD22720.1 - 0.00036 20.8 17.9 0.00055 20.3 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCD22720.1 - 0.0055 17.1 14.5 0.0084 16.5 3.3 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCD22720.1 - 0.075 13.9 1.0 0.075 13.9 1.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 CCD22720.1 - 0.17 12.3 0.2 0.17 12.3 0.2 3.1 2 1 1 3 3 3 0 Zinc-finger of C2H2 type DUF2895 PF11444.8 CCD22720.1 - 0.5 9.7 3.0 0.36 10.2 0.4 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2895) DUF2718 PF10918.8 CCD22721.1 - 0.04 14.4 1.1 0.073 13.6 0.0 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2718) FtsH_ext PF06480.15 CCD22721.1 - 0.15 12.4 0.9 18 5.8 0.0 2.2 2 0 0 2 2 2 0 FtsH Extracellular Ribosomal_S10 PF00338.22 CCD22722.1 - 5.7e-31 106.7 0.0 8.4e-31 106.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e E1-E2_ATPase PF00122.20 CCD22723.1 - 5.4e-35 120.5 10.4 1.2e-30 106.4 0.0 3.5 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CCD22723.1 - 1.4e-28 99.9 0.5 1.4e-28 99.9 0.5 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CCD22723.1 - 1.7e-21 77.5 0.0 4.1e-20 73.0 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCD22723.1 - 1.5e-19 69.8 0.0 2.9e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CCD22723.1 - 7.8e-13 47.9 0.0 2.6e-12 46.3 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CCD22723.1 - 0.00058 19.7 4.2 0.0014 18.4 0.8 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Wzy_C PF04932.15 CCD22723.1 - 0.033 13.8 1.6 1.3 8.7 0.1 2.9 3 0 0 3 3 3 0 O-Antigen ligase tRNA-synt_2 PF00152.20 CCD22724.1 - 7.1e-75 252.0 0.5 7.1e-75 252.0 0.5 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCD22724.1 - 3.4e-12 46.2 0.4 7e-12 45.2 0.4 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CCD22724.1 - 4.3e-07 29.7 0.0 0.0035 16.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DnaJ PF00226.31 CCD22724.1 - 0.029 14.5 0.1 0.32 11.1 0.0 2.5 2 0 0 2 2 2 0 DnaJ domain Pkinase PF00069.25 CCD22725.1 - 1.9e-37 129.1 0.3 1.9e-37 129.1 0.3 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22725.1 - 1.3e-22 80.3 0.1 1.3e-22 80.3 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CCD22725.1 - 0.014 15.4 1.8 2.5 7.9 0.0 2.7 3 0 0 3 3 3 0 Phosphotransferase enzyme family ECH_2 PF16113.5 CCD22726.1 - 1.1e-88 297.9 0.0 1.4e-88 297.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CCD22726.1 - 3.6e-27 95.3 0.0 5.5e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RIH_assoc PF08454.11 CCD22726.1 - 0.25 11.2 3.7 5.8 6.8 0.1 2.9 2 1 0 2 2 2 0 RyR and IP3R Homology associated Wtap PF17098.5 CCD22727.1 - 0.004 17.1 14.2 0.011 15.6 14.2 2.1 1 1 0 1 1 1 1 WTAP/Mum2p family Pro_dh PF01619.18 CCD22727.1 - 0.04 13.5 1.7 0.058 12.9 1.2 1.5 1 1 0 1 1 1 0 Proline dehydrogenase DUF4407 PF14362.6 CCD22727.1 - 0.68 9.2 7.9 0.23 10.8 3.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4351 PF14261.6 CCD22727.1 - 0.69 10.0 4.6 0.81 9.8 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4351) Retrotrans_gag PF03732.17 CCD22727.1 - 3.6 7.9 8.1 0.33 11.2 0.5 3.0 4 0 0 4 4 4 0 Retrotransposon gag protein DAHP_synth_1 PF00793.20 CCD22728.1 - 3.2e-104 347.7 0.0 3.8e-104 347.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family CYSTM PF12734.7 CCD22729.1 - 9.7e-08 32.2 31.3 1.4e-06 28.5 31.3 2.3 1 1 0 1 1 1 1 Cysteine-rich TM module stress tolerance Fungal_trans_2 PF11951.8 CCD22730.1 - 2.2e-25 89.3 0.2 2.2e-25 89.3 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD22730.1 - 2.6e-07 30.6 12.2 5.2e-07 29.7 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRP1_N PF06424.12 CCD22731.1 - 8.3e-22 78.2 13.3 5.8e-16 59.2 0.1 3.1 2 1 1 3 3 3 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 CCD22731.1 - 1.5e-20 72.1 0.0 0.013 16.3 0.0 9.6 7 3 4 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 CCD22731.1 - 6.3e-18 65.0 0.1 0.0037 17.7 0.0 6.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCD22731.1 - 7.1e-11 41.4 10.0 0.012 15.7 0.0 8.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCD22731.1 - 9.6e-11 41.3 7.5 0.21 12.0 0.0 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCD22731.1 - 7.6e-07 29.3 2.2 2.5 8.5 0.1 5.9 5 1 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CCD22731.1 - 5.7e-06 26.9 0.0 0.085 13.5 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.8 CCD22731.1 - 2.4e-05 23.5 0.3 0.097 11.6 0.2 3.4 2 1 2 4 4 4 2 NMDA receptor-regulated protein 1 ChAPs PF09295.10 CCD22731.1 - 0.00028 20.0 1.2 1.4 7.8 0.3 3.5 3 1 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 CCD22731.1 - 0.0017 18.5 1.6 0.41 10.9 0.5 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CCD22731.1 - 0.0017 18.1 14.7 0.039 13.8 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCD22731.1 - 0.0021 18.1 19.9 0.033 14.4 0.2 6.3 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCD22731.1 - 0.0047 16.9 0.6 37 4.7 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 CCD22731.1 - 0.0085 16.7 6.3 32 5.5 0.1 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SPO22 PF08631.10 CCD22731.1 - 0.028 13.9 10.9 0.24 10.8 0.2 4.5 3 2 2 5 5 5 0 Meiosis protein SPO22/ZIP4 like TPR_11 PF13414.6 CCD22731.1 - 0.085 12.6 5.3 1.6 8.5 0.0 4.9 7 0 0 7 7 7 0 TPR repeat TPR_9 PF13371.6 CCD22731.1 - 0.11 12.7 0.0 1.3e+02 2.9 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 CCD22731.1 - 0.24 11.3 0.8 31 4.6 0.0 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Bac_rhodopsin PF01036.18 CCD22732.1 - 4.9e-44 150.6 18.3 6.6e-44 150.1 18.3 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1772 PF08592.11 CCD22732.1 - 3.4 8.0 8.4 2.6 8.4 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Use1 PF09753.9 CCD22732.1 - 6.2 6.5 5.5 14 5.3 5.5 1.5 1 0 0 1 1 1 0 Membrane fusion protein Use1 FMN_red PF03358.15 CCD22733.1 - 7.7e-12 45.2 0.0 9.9e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CCD22733.1 - 0.00017 21.3 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 CCD22733.1 - 0.0048 17.1 0.4 0.025 14.8 0.4 2.1 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 CCD22733.1 - 0.035 14.3 0.0 0.73 10.1 0.0 2.1 1 1 1 2 2 2 0 Flavodoxin domain WD40 PF00400.32 CCD22734.1 - 1.4e-11 44.8 6.7 0.039 14.8 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD22734.1 - 1.6e-05 25.1 1.0 27 5.1 0.0 5.5 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5503 PF17607.2 CCD22734.1 - 0.039 14.3 0.1 0.11 12.9 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5503) DUF1752 PF08550.10 CCD22735.1 - 1.5e-12 47.1 3.9 3.7e-12 45.8 3.9 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) FoP_duplication PF13865.6 CCD22735.1 - 1.8 9.2 8.5 0.053 14.1 1.7 1.9 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Vps54_N PF10475.9 CCD22736.1 - 5e-06 26.0 7.5 1.4e-05 24.6 7.5 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Vps54 PF07928.12 CCD22736.1 - 0.0011 19.4 0.3 0.007 16.8 0.3 2.5 1 1 0 1 1 1 1 Vps54-like protein DUF3364 PF11844.8 CCD22736.1 - 0.03 14.6 0.1 0.13 12.5 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3364) Myb_DNA-binding PF00249.31 CCD22737.1 - 1.1e-20 73.6 11.3 3.9e-11 43.0 0.2 3.9 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCD22737.1 - 9.8e-17 61.0 10.0 3.9e-14 52.6 1.4 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain CMS1 PF14617.6 CCD22737.1 - 6.2 6.1 15.0 4.9 6.4 2.6 2.3 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Ribosomal_S17_N PF16205.5 CCD22738.1 - 3.9e-31 107.2 0.8 6.9e-31 106.4 0.8 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CCD22738.1 - 3.4e-27 94.3 4.5 3.4e-27 94.3 4.5 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 DUF922 PF06037.11 CCD22738.1 - 0.091 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) tRNA-synt_2b PF00587.25 CCD22739.1 - 3e-33 115.3 0.0 5.1e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CCD22739.1 - 3.1e-20 72.4 9.5 3.1e-20 72.4 9.5 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Atg31 PF09795.9 CCD22740.1 - 2.6e-61 206.2 9.6 3e-61 206.0 9.6 1.0 1 0 0 1 1 1 1 Autophagy-related protein 31 DEAD PF00270.29 CCD22741.1 - 1.1e-42 145.7 1.8 2.1e-42 144.9 1.8 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD22741.1 - 6.3e-34 116.7 1.6 2.8e-32 111.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD22741.1 - 2.7e-05 24.2 0.1 4.8e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CCD22741.1 - 0.0013 18.5 0.1 0.0032 17.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CCD22741.1 - 0.0018 18.6 0.3 0.012 15.9 0.2 2.0 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.6 CCD22741.1 - 0.0019 17.6 1.5 0.004 16.5 0.1 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 CCD22741.1 - 0.017 15.0 0.0 0.042 13.7 0.0 1.6 1 1 0 1 1 1 0 Helicase AAA_22 PF13401.6 CCD22741.1 - 0.018 15.3 1.9 0.084 13.1 1.9 2.0 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.25 CCD22741.1 - 0.022 14.1 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) PRK PF00485.18 CCD22742.1 - 1.4e-05 24.9 0.4 0.00036 20.3 0.4 2.6 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family GCV_T PF01571.21 CCD22743.1 - 3.3e-71 239.7 0.0 3.9e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CCD22743.1 - 7.4e-13 48.2 0.0 1.4e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 CCD22743.1 - 0.0029 17.8 0.0 0.0084 16.3 0.0 1.8 2 0 0 2 2 2 1 Sarcosine oxidase, gamma subunit family Acyltransferase PF01553.21 CCD22744.1 - 5e-26 90.9 0.1 8.7e-26 90.1 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CCD22744.1 - 1.9e-13 50.3 0.0 4.3e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Cation_ATPase_N PF00690.26 CCD22744.1 - 0.45 10.2 3.6 6.6 6.5 0.2 2.7 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus IPK PF03770.16 CCD22745.1 - 1.6e-47 161.9 0.3 6.6e-47 159.9 0.3 2.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase CENP-B_dimeris PF09026.10 CCD22745.1 - 0.016 15.6 3.5 0.016 15.6 3.5 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PfkB PF00294.24 CCD22745.1 - 0.55 9.5 3.5 14 4.8 0.1 2.4 2 0 0 2 2 2 0 pfkB family carbohydrate kinase DASH_Dad1 PF08649.10 CCD22746.1 - 9.7e-23 80.1 1.0 1.4e-22 79.6 1.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad1 2-oxogl_dehyd_N PF16078.5 CCD22746.1 - 0.073 12.7 0.2 0.16 11.6 0.1 1.6 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus CRCB PF02537.15 CCD22748.1 - 5.6e-31 106.7 17.6 1.7e-18 66.7 4.4 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Wap1 PF16997.5 CCD22749.1 - 1.1e-29 103.8 5.1 1.9e-29 103.0 5.1 1.4 1 0 0 1 1 1 1 Wap1 domain Nab2 PF11517.8 CCD22749.1 - 0.0068 16.7 0.4 0.019 15.2 0.4 1.7 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Sld5 PF05916.11 CCD22750.1 - 5.2e-09 36.5 2.2 9.2e-09 35.7 2.2 1.4 1 0 0 1 1 1 1 GINS complex protein AKNA PF12443.8 CCD22750.1 - 0.029 15.0 3.2 0.07 13.8 3.2 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor Methyltransf_25 PF13649.6 CCD22751.1 - 8.8e-13 48.8 0.1 4.8e-12 46.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CCD22751.1 - 3.3e-12 46.4 0.1 8.9e-12 45.0 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CCD22751.1 - 4.1e-10 39.7 0.1 1.2e-09 38.2 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCD22751.1 - 3e-09 37.4 0.0 1.3e-08 35.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCD22751.1 - 3.5e-08 33.5 0.0 2.3e-07 30.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CCD22751.1 - 2.7e-07 30.1 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 CCD22751.1 - 2.1e-06 26.9 0.0 2.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 CCD22751.1 - 5.5e-05 22.8 0.1 9.3e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CCD22751.1 - 6.2e-05 23.7 0.2 0.00022 21.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 CCD22751.1 - 0.0001 22.4 0.0 0.0018 18.4 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 CCD22751.1 - 0.00035 20.5 0.0 0.00068 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CCD22751.1 - 0.0014 18.4 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 CCD22751.1 - 0.0031 17.2 0.1 0.0054 16.5 0.1 1.4 1 0 0 1 1 1 1 Lysine methyltransferase PRMT5 PF05185.16 CCD22751.1 - 0.0034 17.3 0.1 0.0057 16.5 0.1 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Ubie_methyltran PF01209.18 CCD22751.1 - 0.0073 15.7 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 CCD22751.1 - 0.015 14.7 0.1 0.032 13.7 0.1 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 CCD22751.1 - 0.042 13.8 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 CCD22751.1 - 0.043 13.6 0.1 0.071 12.8 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.17 CCD22751.1 - 0.15 11.5 0.1 0.36 10.3 0.1 1.6 1 0 0 1 1 1 0 Putative methyltransferase Ribosomal_L4 PF00573.22 CCD22752.1 - 4.6e-44 150.4 1.6 1e-43 149.3 1.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CCD22752.1 - 3.2e-29 100.8 4.2 6.4e-29 99.8 0.7 2.6 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain SET PF00856.28 CCD22753.1 - 1.2e-14 55.1 1.8 1.3e-08 35.4 0.0 3.4 3 0 0 3 3 3 2 SET domain Phage_lysozyme PF00959.19 CCD22753.1 - 0.11 12.9 0.1 0.53 10.8 0.0 2.1 2 0 0 2 2 2 0 Phage lysozyme MPP6 PF10175.9 CCD22753.1 - 0.14 12.7 0.3 0.14 12.7 0.3 2.2 3 0 0 3 3 3 0 M-phase phosphoprotein 6 Aha1_N PF09229.11 CCD22754.1 - 2.8e-27 95.6 0.5 3.3e-27 95.4 0.5 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal RNase_P_pop3 PF08228.11 CCD22755.1 - 4.3e-42 143.8 0.1 6.6e-42 143.2 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 WSC PF01822.19 CCD22756.1 - 1.8e-10 40.9 10.3 7.6e-10 38.8 10.3 2.2 1 0 0 1 1 1 1 WSC domain Adeno_E3_CR2 PF02439.15 CCD22756.1 - 2.3e-05 24.0 3.2 5e-05 23.0 3.2 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 CCD22756.1 - 2.7e-05 23.5 3.0 0.00012 21.4 3.0 2.2 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.20 CCD22756.1 - 0.00065 19.6 0.1 0.0014 18.5 0.1 1.5 1 0 0 1 1 1 1 Syndecan domain EphA2_TM PF14575.6 CCD22756.1 - 0.042 14.7 0.2 0.19 12.7 0.0 2.2 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ribosomal_L27A PF00828.19 CCD22757.1 - 1.6e-32 112.8 0.7 1.6e-32 112.8 0.7 1.9 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Adaptin_N PF01602.20 CCD22758.1 - 1.9e-111 373.2 11.5 2.6e-111 372.8 11.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CCD22758.1 - 1.7e-46 158.1 1.7 5.6e-46 156.4 1.7 2.0 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CCD22758.1 - 6.8e-27 93.9 0.2 1.8e-26 92.5 0.2 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CCD22758.1 - 2.6e-12 47.0 0.1 2.8e-07 30.8 0.1 4.6 3 1 1 4 4 4 1 HEAT repeats Cnd1 PF12717.7 CCD22758.1 - 7.4e-07 29.3 13.9 6.9e-05 22.9 0.8 5.0 4 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CCD22758.1 - 0.016 15.4 0.6 3 8.3 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 CCD22758.1 - 0.041 14.4 0.3 0.25 11.9 0.3 2.5 1 1 0 1 1 1 0 HEAT-like repeat PPP5 PF08321.12 CCD22758.1 - 0.062 13.6 0.6 22 5.4 0.1 2.8 2 0 0 2 2 2 0 PPP5 TPR repeat region FANCI_S2 PF14676.6 CCD22758.1 - 4.9 7.4 7.7 53 4.1 0.2 4.1 4 1 0 4 4 4 0 FANCI solenoid 2 Rcd1 PF04078.13 CCD22759.1 - 1.4e-112 375.2 3.0 1.7e-112 375.0 3.0 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like SRX PF09201.10 CCD22759.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 SRX, signal recognition particle receptor alpha subunit Cyclin_N PF00134.23 CCD22760.1 - 1.5e-22 79.7 0.0 7.7e-22 77.4 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCD22760.1 - 8.7e-07 29.4 0.0 1.9e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin AAA PF00004.29 CCD22761.1 - 1.3e-17 64.5 0.0 2.2e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CCD22761.1 - 6.1e-17 61.9 0.0 6.2e-12 45.6 0.1 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 CCD22761.1 - 7.4e-14 51.9 0.1 2.4e-13 50.3 0.0 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 CCD22761.1 - 1.8e-07 31.2 0.0 1.1e-06 28.7 0.0 2.1 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 CCD22761.1 - 3.8e-07 30.3 0.0 1.1e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 CCD22761.1 - 4.1e-06 27.3 0.0 6.8e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain DNA_pol3_delta PF06144.13 CCD22761.1 - 6.8e-06 26.0 0.2 1.1e-05 25.3 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 CCD22761.1 - 8.2e-06 25.6 0.0 1.7e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 CCD22761.1 - 1.2e-05 25.4 0.0 0.0031 17.5 0.0 2.3 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCD22761.1 - 1.3e-05 25.4 0.7 0.14 12.5 0.1 2.7 2 1 1 3 3 3 2 AAA domain AAA_11 PF13086.6 CCD22761.1 - 4.5e-05 23.4 0.1 0.00035 20.4 0.0 1.9 1 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CCD22761.1 - 4.8e-05 23.4 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CCD22761.1 - 6.5e-05 22.2 0.0 9.6e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 CCD22761.1 - 6.9e-05 22.7 0.0 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CCD22761.1 - 0.00052 19.8 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 CCD22761.1 - 0.00086 19.3 0.1 0.0042 17.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CCD22761.1 - 0.00087 19.1 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CCD22761.1 - 0.0012 18.4 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 CCD22761.1 - 0.0015 19.1 0.1 0.0037 17.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 CCD22761.1 - 0.0025 17.6 0.1 0.018 14.8 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 CCD22761.1 - 0.0027 17.5 0.0 0.008 15.9 0.0 1.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CCD22761.1 - 0.0034 17.7 0.2 0.18 12.1 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 CCD22761.1 - 0.0065 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CCD22761.1 - 0.015 14.9 0.3 0.26 10.8 0.0 2.5 2 1 1 3 3 3 0 AAA domain Mg_chelatase PF01078.21 CCD22761.1 - 0.018 14.4 0.0 0.099 12.0 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CCD22761.1 - 0.03 14.7 0.0 0.059 13.8 0.0 1.6 1 1 0 1 1 1 0 RNA helicase TIP49 PF06068.13 CCD22761.1 - 0.034 13.3 0.0 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain TniB PF05621.11 CCD22761.1 - 0.05 13.0 0.0 1.4 8.3 0.0 2.4 2 1 1 3 3 3 0 Bacterial TniB protein AAA_28 PF13521.6 CCD22761.1 - 0.051 13.8 0.0 0.092 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CCD22761.1 - 0.052 13.0 0.0 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 CCD22761.1 - 0.058 13.9 0.1 0.27 11.8 0.0 2.1 1 1 0 1 1 1 0 ABC transporter SNF2_N PF00176.23 CCD22761.1 - 0.073 11.8 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Methyltransf_31 PF13847.6 CCD22761.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AAA_33 PF13671.6 CCD22761.1 - 0.096 12.8 0.1 0.25 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CCD22761.1 - 0.15 11.3 0.1 0.63 9.2 0.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mid1 PF12929.7 CCD22762.1 - 4e-129 431.5 13.6 4.9e-129 431.3 13.6 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 CCD22762.1 - 0.005 17.4 4.3 0.26 11.9 4.3 2.6 1 1 0 1 1 1 1 Fz domain TruB_N PF01509.18 CCD22763.1 - 9.2e-41 139.7 1.0 2.4e-39 135.1 0.0 2.8 3 0 0 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 CCD22763.1 - 0.00032 20.8 0.0 0.0023 18.0 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain KinB_sensor PF16767.5 CCD22763.1 - 0.61 10.6 4.3 1.1 9.7 1.1 2.7 3 0 0 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB RabGAP-TBC PF00566.18 CCD22764.1 - 2.8e-43 148.1 4.6 6.4e-31 107.7 0.1 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PalH PF08733.10 CCD22765.1 - 5.2e-86 288.7 16.2 6.4e-86 288.3 16.2 1.1 1 0 0 1 1 1 1 PalH/RIM21 Cloacin_immun PF03513.14 CCD22765.1 - 0.002 18.5 0.8 0.0096 16.2 0.3 2.3 2 0 0 2 2 2 1 Cloacin immunity protein Wzy_C PF04932.15 CCD22765.1 - 0.6 9.7 5.1 12 5.5 0.0 2.4 2 1 0 2 2 2 0 O-Antigen ligase Pet20 PF08692.10 CCD22766.1 - 9e-34 117.0 2.6 9.2e-34 116.9 0.0 2.3 3 0 0 3 3 3 1 Mitochondrial protein Pet20 DCB PF16213.5 CCD22767.1 - 1e-52 178.4 0.9 1e-52 178.4 0.9 3.2 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 CCD22767.1 - 1.8e-36 125.4 7.1 1.8e-36 125.4 7.1 5.1 6 1 0 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 CCD22767.1 - 5.5e-17 61.2 0.2 2.8e-11 42.4 0.0 2.5 2 0 0 2 2 2 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 CCD22767.1 - 0.052 13.4 0.1 0.46 10.4 0.1 2.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) Pkinase PF00069.25 CCD22768.1 - 1.6e-64 217.8 0.3 4.5e-64 216.4 0.3 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22768.1 - 1.6e-50 171.9 0.0 2.7e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CCD22768.1 - 6.9e-24 84.0 0.2 2.1e-23 82.4 0.2 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 CCD22768.1 - 1.8e-12 47.7 0.7 4.5e-12 46.4 0.7 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 CCD22768.1 - 2.1e-06 27.3 0.0 3.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CCD22768.1 - 1.1e-05 24.4 0.0 1.1e-05 24.4 0.0 1.9 2 1 0 2 2 2 1 Fungal protein kinase PH_11 PF15413.6 CCD22768.1 - 2.3e-05 24.7 1.5 2.3e-05 24.7 1.5 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain APH PF01636.23 CCD22768.1 - 0.039 13.9 0.2 0.1 12.5 0.2 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family NTP_transf_2 PF01909.23 CCD22769.1 - 1.5e-18 66.8 0.1 1.5e-18 66.8 0.1 3.0 2 1 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CCD22769.1 - 1.6e-14 53.8 0.0 1.6e-14 53.8 0.0 2.2 2 0 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 CCD22769.1 - 0.0028 17.7 0.0 0.012 15.7 0.0 2.1 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DUF2852 PF11014.8 CCD22769.1 - 1.3 9.2 5.6 3.8 7.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) Ribosomal_L18 PF17135.4 CCD22770.1 - 9.4e-88 292.5 1.8 1e-87 292.4 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CCD22770.1 - 0.0026 18.4 0.2 0.0065 17.1 0.2 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Nudc_N PF14050.6 CCD22770.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. Ribosomal_S19e PF01090.19 CCD22771.1 - 2.2e-53 179.6 0.1 2.5e-53 179.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e RRM_1 PF00076.22 CCD22772.1 - 5e-33 112.7 0.2 4.5e-17 61.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD22772.1 - 5.8e-13 48.8 0.2 2.4e-07 30.8 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif RPN2_C PF18004.1 CCD22772.1 - 0.7 9.8 21.8 1.6 8.6 21.8 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Ras PF00071.22 CCD22773.1 - 5.1e-28 97.7 0.1 2.5e-23 82.5 0.1 2.5 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CCD22773.1 - 5.5e-15 55.6 4.8 3.5e-09 36.9 0.0 3.0 3 1 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 CCD22773.1 - 0.0013 18.2 0.1 0.0037 16.8 0.1 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 CCD22773.1 - 0.0024 17.3 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein Borrelia_orfD PF02999.14 CCD22773.1 - 0.13 12.6 2.6 0.3 11.4 1.9 2.0 1 1 0 1 1 1 0 Borrelia orf-D family Bax1-I PF01027.20 CCD22774.1 - 3.4e-42 144.6 21.7 4.6e-42 144.2 21.7 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PAP2 PF01569.21 CCD22774.1 - 5.1 6.9 16.6 9.6 6.0 13.3 2.8 2 1 0 2 2 2 0 PAP2 superfamily Ribosomal_L23 PF00276.20 CCD22775.1 - 5.1e-14 52.4 3.3 3.3e-13 49.8 3.3 1.9 1 1 0 1 1 1 1 Ribosomal protein L23 Ribosomal_S11 PF00411.19 CCD22776.1 - 2.1e-07 31.3 0.0 3.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 UPF0220 PF05255.11 CCD22777.1 - 7.2e-54 181.8 4.3 8.3e-54 181.6 4.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Kri1_C PF12936.7 CCD22778.1 - 1.3e-30 105.4 3.0 1.3e-30 105.4 3.0 5.3 6 1 1 7 7 7 1 KRI1-like family C-terminal Kri1 PF05178.12 CCD22778.1 - 1.9e-15 57.3 17.5 1.9e-15 57.3 17.5 6.7 4 3 5 9 9 9 1 KRI1-like family YtzH PF14165.6 CCD22778.1 - 0.049 14.0 6.0 0.57 10.6 0.5 3.1 2 0 0 2 2 2 0 YtzH-like protein CorA PF01544.18 CCD22779.1 - 5.6e-38 130.9 7.9 1.7e-23 83.4 1.0 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein zf-DNL PF05180.12 CCD22781.1 - 1.3e-31 108.3 2.1 2.1e-31 107.7 2.1 1.3 1 0 0 1 1 1 1 DNL zinc finger UPF0167 PF03691.14 CCD22781.1 - 0.03 14.1 0.1 0.041 13.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) zinc_ribbon_4 PF13717.6 CCD22781.1 - 0.041 13.8 0.5 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 CCD22781.1 - 0.13 12.3 1.0 0.2 11.7 1.0 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TFIIS_C PF01096.18 CCD22781.1 - 3.4 7.6 5.4 42 4.1 5.6 2.3 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) SGL PF08450.12 CCD22782.1 - 2.1e-55 188.0 0.0 3.5e-55 187.3 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 CCD22782.1 - 6.6e-05 23.0 0.0 3 8.1 0.0 3.4 3 0 0 3 3 3 3 Arylesterase DUF1752 PF08550.10 CCD22783.1 - 1.5 8.7 6.7 0.12 12.3 0.7 2.2 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1752) Myb_DNA-binding PF00249.31 CCD22784.1 - 2.6e-20 72.4 15.0 6.4e-12 45.5 2.4 4.5 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCD22784.1 - 1.6e-17 63.5 15.9 8.5e-15 54.7 5.2 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 CCD22784.1 - 0.0094 16.1 1.3 0.043 14.0 0.2 2.6 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 DXP_reductoisom PF02670.16 CCD22784.1 - 1.8 9.3 7.8 1.8 9.3 0.7 2.9 3 0 0 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase E1-E2_ATPase PF00122.20 CCD22785.1 - 0.21 11.1 0.6 0.31 10.5 0.0 1.5 2 0 0 2 2 2 0 E1-E2 ATPase ADH_zinc_N PF00107.26 CCD22786.1 - 4.9e-24 84.8 0.0 8.5e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCD22786.1 - 1.9e-14 54.9 0.0 4.2e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCD22786.1 - 5.6e-09 35.9 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 CCD22786.1 - 0.015 14.8 0.2 0.022 14.2 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 CCD22786.1 - 0.094 13.0 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Prog_receptor PF02161.15 CCD22787.1 - 0.041 12.6 0.2 0.064 12.0 0.2 1.2 1 0 0 1 1 1 0 Progesterone receptor Acyltransferase PF01553.21 CCD22790.1 - 9.2e-31 106.3 0.0 4.2e-30 104.1 0.0 2.0 1 1 1 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 CCD22790.1 - 9.5e-14 51.3 0.4 1.7e-13 50.5 0.4 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus AMP-binding PF00501.28 CCD22791.1 - 5.5e-54 183.4 0.0 6.7e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCD22791.1 - 0.0021 19.0 0.1 0.0038 18.2 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fig1 PF12351.8 CCD22792.1 - 2.2e-56 190.7 6.6 2.2e-56 190.7 6.6 1.6 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 CCSMST1 PF15013.6 CCD22792.1 - 0.64 10.2 0.0 0.64 10.2 0.0 3.0 3 0 0 3 3 3 0 CCSMST1 family ATP-synt PF00231.19 CCD22793.1 - 1.2e-70 238.4 5.1 1.3e-70 238.3 5.1 1.0 1 0 0 1 1 1 1 ATP synthase Methyltransf_25 PF13649.6 CCD22794.1 - 4.1e-13 49.8 0.0 5.3e-12 46.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CCD22794.1 - 4.8e-12 45.9 0.0 7.2e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CCD22794.1 - 5.5e-10 39.2 0.0 1.5e-09 37.8 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCD22794.1 - 8.1e-10 39.2 0.0 8.9e-09 35.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCD22794.1 - 3.9e-07 30.1 0.0 8.9e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CCD22794.1 - 1.3e-06 27.6 0.1 1.7e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 CCD22794.1 - 2.4e-05 24.0 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 CCD22794.1 - 3.6e-05 23.2 0.0 5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 CCD22794.1 - 8.4e-05 22.5 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCD22794.1 - 0.00025 21.7 0.0 0.00052 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 CCD22794.1 - 0.00039 19.8 0.0 0.00078 18.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_16 PF10294.9 CCD22794.1 - 0.00058 19.6 0.0 0.0009 19.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 CCD22794.1 - 0.0055 16.8 0.0 0.0099 16.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 CCD22794.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 CCD22794.1 - 0.022 14.1 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 CCD22794.1 - 0.027 14.2 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.19 CCD22794.1 - 0.095 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 CCD22794.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PRMT5 PF05185.16 CCD22794.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PNP_phzG_C PF10590.9 CCD22795.1 - 6.2e-21 74.2 3.4 1.5e-20 73.0 3.4 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 CCD22795.1 - 2.7e-10 40.3 0.0 4.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase KdpC PF02669.15 CCD22795.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Carn_acyltransf PF00755.20 CCD22796.1 - 1.8e-205 684.0 0.6 2.3e-205 683.7 0.6 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Oxysterol_BP PF01237.18 CCD22797.1 - 1.2e-132 442.3 0.0 1.2e-132 442.3 0.0 1.8 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 CCD22797.1 - 2.8e-14 53.0 0.1 1.7e-05 25.0 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.29 CCD22797.1 - 6.9e-13 49.0 0.5 2.1e-12 47.5 0.5 1.9 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 CCD22797.1 - 3.6e-12 46.5 0.3 0.00031 21.2 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCD22797.1 - 5.7e-12 44.7 0.1 0.0016 18.8 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 CCD22797.1 - 4.7e-10 39.9 0.0 0.0022 18.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) PH_8 PF15409.6 CCD22797.1 - 8.7e-09 35.6 0.2 3.1e-08 33.8 0.2 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Ank PF00023.30 CCD22797.1 - 3.5e-07 30.4 0.1 0.022 15.2 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat PH_11 PF15413.6 CCD22797.1 - 0.0002 21.8 4.2 0.0025 18.2 2.3 3.5 2 1 0 2 2 2 1 Pleckstrin homology domain zf-C2H2 PF00096.26 CCD22798.1 - 0.00047 20.4 8.6 0.1 13.1 0.4 3.2 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD22798.1 - 0.024 15.4 5.6 2.9 9.0 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCD22798.1 - 0.027 14.5 4.3 3.4 7.8 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCD22798.1 - 0.03 14.7 2.2 1.2 9.7 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CCD22798.1 - 0.13 12.6 1.1 20 5.6 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding SAICAR_synt PF01259.18 CCD22799.1 - 1.2e-101 339.6 0.2 1.4e-101 339.4 0.2 1.0 1 0 0 1 1 1 1 SAICAR synthetase EMP24_GP25L PF01105.24 CCD22800.1 - 3.5e-30 105.3 0.4 4.5e-30 104.9 0.4 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2207 PF09972.9 CCD22800.1 - 0.025 13.4 0.4 0.025 13.4 0.4 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Pkinase PF00069.25 CCD22801.1 - 5.6e-39 134.1 0.0 6.3e-22 78.2 0.0 3.8 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22801.1 - 3.6e-14 52.7 0.0 5.6e-10 38.9 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 CCD22801.1 - 0.0061 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CCD22801.1 - 0.14 11.5 0.0 12 5.1 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Steroid_dh PF02544.16 CCD22802.1 - 1e-34 119.7 10.4 1.7e-34 119.0 10.4 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Fibrillarin PF01269.17 CCD22803.1 - 7.4e-108 358.9 0.0 8.9e-108 358.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CCD22803.1 - 7.1e-06 25.9 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 CCD22803.1 - 0.0057 16.8 0.0 0.0076 16.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 CCD22803.1 - 0.067 12.8 0.0 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 CCD22803.1 - 0.092 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Mannosyl_trans3 PF11051.8 CCD22804.1 - 1.8e-81 273.5 0.1 3.7e-81 272.5 0.1 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative zf-RING_5 PF14634.6 CCD22805.1 - 0.0013 18.6 0.2 0.0028 17.6 0.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CCD22805.1 - 0.0019 18.0 0.1 0.0044 16.8 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCD22805.1 - 0.0037 17.3 0.6 0.0082 16.2 0.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CCD22805.1 - 0.005 16.7 0.1 0.013 15.3 0.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 IBR PF01485.21 CCD22805.1 - 0.0061 16.8 1.1 0.42 10.9 0.2 2.4 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 CCD22805.1 - 0.0061 16.4 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCD22805.1 - 0.073 13.2 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CCD22805.1 - 0.16 12.3 0.1 0.41 11.0 0.1 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_11 PF17123.5 CCD22805.1 - 0.21 11.4 0.3 0.51 10.1 0.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 CCD22806.1 - 1.7e-41 140.2 2.7 2.5e-41 139.6 2.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CCD22806.1 - 3.4e-22 78.5 10.2 5.1e-22 77.9 10.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CCD22806.1 - 1.1e-06 28.8 16.9 1.4e-05 25.3 16.9 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CCD22806.1 - 0.00024 20.9 5.5 0.00024 20.9 5.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCD22806.1 - 0.0075 16.3 10.9 0.039 14.0 7.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CCD22806.1 - 0.016 15.0 15.2 0.091 12.7 15.2 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CCD22806.1 - 0.019 15.1 17.1 0.36 11.0 17.1 3.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 CCD22806.1 - 0.02 15.0 3.0 0.02 15.0 3.0 2.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CCD22806.1 - 0.026 14.3 2.1 0.026 14.3 2.1 2.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CCD22806.1 - 0.038 13.8 12.8 1.9 8.4 12.9 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCD22806.1 - 0.22 11.5 13.7 0.79 9.7 13.9 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 CCD22806.1 - 0.3 10.9 10.3 1.4 8.7 10.3 2.1 1 1 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 CCD22806.1 - 0.38 10.4 7.9 0.89 9.2 7.9 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 CCD22806.1 - 0.59 10.3 6.4 0.61 10.3 5.1 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HIT PF04438.16 CCD22806.1 - 1.8 8.5 8.8 0.56 10.1 4.2 2.1 2 0 0 2 2 2 0 HIT zinc finger RINGv PF12906.7 CCD22806.1 - 3 8.1 7.8 8.3 6.6 7.8 1.8 1 1 0 1 1 1 0 RING-variant domain Tcp11 PF05794.13 CCD22807.1 - 4.7e-135 451.1 1.9 4.7e-135 451.1 1.9 1.8 2 0 0 2 2 2 1 T-complex protein 11 Maf1 PF09174.10 CCD22808.1 - 1.1e-45 155.9 11.4 2.8e-40 138.3 1.1 2.5 1 1 0 2 2 2 2 Maf1 regulator Macoilin PF09726.9 CCD22808.1 - 1.7 7.1 17.1 2 6.8 17.1 1.1 1 0 0 1 1 1 0 Macoilin family Rad51 PF08423.11 CCD22809.1 - 5.3e-48 163.5 0.2 4.7e-43 147.3 0.1 2.3 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 CCD22809.1 - 1.2e-07 31.6 0.0 2.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 CCD22809.1 - 2.3e-05 24.0 0.6 5.7e-05 22.7 0.6 1.6 1 1 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CCD22809.1 - 0.00044 19.7 5.5 0.013 14.9 5.5 2.6 1 1 0 1 1 1 1 KaiC AAA_24 PF13479.6 CCD22809.1 - 0.0095 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RCR PF12273.8 CCD22810.1 - 4.9e-34 117.5 1.8 5.4e-34 117.4 0.4 1.7 1 1 1 2 2 2 1 Chitin synthesis regulation, resistance to Congo red DUF4381 PF14316.6 CCD22810.1 - 0.071 13.3 0.2 0.11 12.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SNARE PF05739.19 CCD22810.1 - 0.098 12.7 3.7 0.19 11.8 3.7 1.5 1 0 0 1 1 1 0 SNARE domain SARAF PF06682.12 CCD22810.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.6 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis PROL5-SMR PF15621.6 CCD22810.1 - 2.7 8.6 6.2 6.5 7.3 0.1 2.4 1 1 1 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family polyprenyl_synt PF00348.17 CCD22811.1 - 7.9e-65 218.4 0.0 3.2e-63 213.2 0.0 2.6 1 1 0 1 1 1 1 Polyprenyl synthetase Cofilin_ADF PF00241.20 CCD22812.1 - 1.8e-27 95.5 1.3 6.8e-13 48.5 0.2 2.4 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein YqaJ PF09588.10 CCD22812.1 - 0.16 12.1 0.3 0.45 10.6 0.1 1.8 2 0 0 2 2 2 0 YqaJ-like viral recombinase domain PI3_PI4_kinase PF00454.27 CCD22813.1 - 4.9e-54 183.8 0.0 1.2e-53 182.5 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 CCD22813.1 - 6.8e-26 90.1 4.4 2.8e-25 88.2 0.2 3.6 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.20 CCD22813.1 - 6.2e-15 54.7 1.8 3.2e-12 46.0 0.0 3.6 3 0 0 3 3 3 1 FATC domain FAT PF02259.23 CCD22813.1 - 0.00025 20.4 4.3 0.00025 20.4 4.3 2.6 2 0 0 2 2 2 1 FAT domain PhaP_Bmeg PF09602.10 CCD22813.1 - 0.037 14.0 2.7 3.7 7.5 0.0 3.2 3 0 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF3385 PF11865.8 CCD22813.1 - 0.3 11.0 1.7 3.1 7.7 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) CKS PF01111.19 CCD22814.1 - 5e-34 116.4 0.1 8.2e-34 115.7 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit SUIM_assoc PF16619.5 CCD22814.1 - 0.00015 21.7 1.7 0.0002 21.3 1.7 1.3 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CCD22814.1 - 4.2 6.9 13.8 5.8 6.5 13.8 1.3 1 0 0 1 1 1 0 Spt20 family PRMT5_TIM PF17285.2 CCD22815.1 - 1.5e-65 221.0 3.9 2.2e-65 220.4 3.9 1.3 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 CCD22815.1 - 4.4e-59 199.2 0.4 1e-58 198.0 0.1 1.8 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 CCD22815.1 - 2.5e-57 193.6 4.8 2.5e-57 193.6 4.8 1.7 2 0 0 2 2 2 1 PRMT5 oligomerisation domain GP120 PF00516.18 CCD22815.1 - 0.038 12.6 0.3 0.087 11.4 0.0 1.7 2 0 0 2 2 2 0 Envelope glycoprotein GP120 Pkinase PF00069.25 CCD22816.1 - 4.4e-53 180.3 0.0 7.9e-53 179.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22816.1 - 1.2e-22 80.4 0.0 2.6e-22 79.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CCD22816.1 - 0.00042 20.0 0.2 0.95 9.0 0.1 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CCD22816.1 - 0.0062 16.5 0.0 0.97 9.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CCD22816.1 - 0.026 13.8 0.1 0.34 10.2 0.0 2.4 3 0 0 3 3 3 0 Kinase-like Kdo PF06293.14 CCD22816.1 - 0.09 12.1 0.2 3.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CCD22816.1 - 0.11 11.3 0.1 0.32 9.7 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 CCD22817.1 - 5.6e-51 173.4 0.2 1.5e-50 172.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22817.1 - 1.6e-23 83.3 0.0 2.6e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CCD22817.1 - 0.018 14.7 3.4 0.23 11.0 0.0 3.2 3 1 1 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 DUF2249 PF10006.9 CCD22817.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) APH PF01636.23 CCD22817.1 - 0.21 11.5 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family NAD_Gly3P_dh_N PF01210.23 CCD22818.1 - 4.3e-53 179.5 0.1 6.8e-53 178.8 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CCD22818.1 - 6.8e-42 143.1 0.3 1.4e-41 142.1 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 CCD22818.1 - 0.035 14.7 0.0 11 6.7 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FCH PF00611.23 CCD22819.1 - 5e-11 42.7 0.4 6.4e-10 39.2 0.0 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.21 CCD22819.1 - 6.4e-11 42.2 0.0 1.7e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 CCD22819.1 - 3.3e-08 33.5 1.2 3.5e-06 26.9 0.0 3.0 2 1 0 2 2 2 1 RhoGAP domain YihI PF04220.12 CCD22819.1 - 0.1 12.4 0.7 0.3 10.8 0.7 1.8 1 0 0 1 1 1 0 Der GTPase activator (YihI) CRC_subunit PF08624.10 CCD22820.1 - 6.8e-34 117.2 0.3 6.8e-34 117.2 0.3 1.8 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit tRNA-synt_2 PF00152.20 CCD22821.1 - 1.5e-61 208.2 0.1 2e-61 207.8 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 CCD22821.1 - 3e-07 30.2 0.2 0.00016 21.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 CCD22821.1 - 1e-05 25.4 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_Me_trans PF03054.16 CCD22822.1 - 2.9e-110 368.4 0.0 3.4e-110 368.2 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 CCD22822.1 - 0.00016 20.9 0.0 0.0012 18.0 0.0 2.1 2 0 0 2 2 2 1 NAD synthase Git3 PF11710.8 CCD22823.1 - 7.9e-79 264.1 11.2 1.6e-78 263.2 11.2 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 CCD22823.1 - 7.4e-27 93.2 1.3 7.4e-27 93.2 1.3 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 CCD22823.1 - 0.0068 15.8 0.0 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) MscS_TM PF12794.7 CCD22823.1 - 0.02 13.8 2.4 0.036 12.9 1.4 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Ost5 PF05251.12 CCD22823.1 - 0.29 11.4 7.7 0.037 14.3 1.6 2.6 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 E1_DerP2_DerF2 PF02221.15 CCD22824.1 - 4.1e-27 95.2 0.1 4.8e-27 95.0 0.1 1.1 1 0 0 1 1 1 1 ML domain CHCH PF06747.13 CCD22825.1 - 0.00011 22.3 0.2 0.00015 21.8 0.2 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 CCD22825.1 - 0.0049 16.9 0.9 0.0058 16.6 0.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Cast PF10174.9 CCD22825.1 - 0.089 11.0 0.0 0.1 10.8 0.0 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone PAPS_reduct PF01507.19 CCD22826.1 - 1.5e-35 122.7 0.0 2.1e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Chromo_2 PF18704.1 CCD22827.1 - 0.072 13.4 0.1 0.24 11.7 0.1 1.9 1 0 0 1 1 1 0 Chromatin organization modifier domain 2 SF3A2 PF16835.5 CCD22828.1 - 1.7e-18 66.8 0.1 3.4e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CCD22828.1 - 1.7e-06 28.2 2.1 4.1e-06 27.0 2.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type OrsD PF12013.8 CCD22828.1 - 0.0042 17.5 0.3 0.01 16.3 0.0 1.8 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 CCD22828.1 - 0.02 15.2 0.3 0.035 14.4 0.3 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) TFIIE_beta PF02186.15 CCD22828.1 - 0.071 13.4 0.1 0.22 11.8 0.1 1.9 1 0 0 1 1 1 0 TFIIE beta subunit core domain zf-U1 PF06220.12 CCD22828.1 - 0.089 12.6 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_jaz PF12171.8 CCD22828.1 - 0.59 10.5 2.2 2.2 8.7 2.2 2.1 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding SIR2 PF02146.17 CCD22829.1 - 3.6e-66 222.4 0.0 7.3e-66 221.5 0.0 1.5 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 CCD22829.1 - 2.8e-63 212.3 1.0 5.6e-63 211.3 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 CCD22829.1 - 0.00048 19.9 0.0 0.47 10.2 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain HLH PF00010.26 CCD22830.1 - 9.4e-16 57.5 0.0 3.8e-15 55.6 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Noelin-1 PF12308.8 CCD22830.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Neurogenesis glycoprotein NAM-associated PF14303.6 CCD22830.1 - 0.092 13.5 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain NARP1 PF12569.8 CCD22831.1 - 1.4e-112 377.2 16.3 2.6e-82 277.4 1.4 3.6 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 CCD22831.1 - 1.3e-11 43.7 9.0 0.0093 16.0 0.0 7.7 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CCD22831.1 - 1.5e-11 44.6 0.4 0.11 13.0 0.0 5.8 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CCD22831.1 - 4.2e-09 36.9 0.0 0.23 12.2 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CCD22831.1 - 7.2e-07 29.5 4.2 0.39 11.6 0.0 6.6 7 1 1 8 8 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCD22831.1 - 3.2e-06 26.9 16.4 0.0039 17.3 0.0 7.0 9 0 0 9 9 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD22831.1 - 9.2e-06 25.8 13.6 0.00059 20.0 0.3 4.8 5 0 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CCD22831.1 - 0.00022 20.9 9.6 0.073 12.9 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCD22831.1 - 0.0014 18.9 6.7 2.3 8.6 0.1 5.9 4 2 3 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCD22831.1 - 0.0033 17.5 6.0 9.6 6.4 0.0 4.5 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 CCD22831.1 - 0.0093 15.8 0.4 16 5.5 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 CCD22831.1 - 0.022 15.4 4.7 1.1 10.1 0.0 6.0 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 CCD22831.1 - 0.031 14.6 9.7 4.4 7.9 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 CCD22831.1 - 0.049 13.3 0.0 0.049 13.3 0.0 3.4 4 0 0 4 4 4 0 TPR repeat TPR_MalT PF17874.1 CCD22831.1 - 0.057 12.8 0.0 1.1 8.5 0.0 2.4 2 1 0 2 2 2 0 MalT-like TPR region Rapsyn_N PF10579.9 CCD22831.1 - 0.067 13.3 0.2 1.7 8.8 0.1 2.8 2 1 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region PglD_N PF17836.1 CCD22831.1 - 0.13 12.9 0.2 0.89 10.2 0.2 2.4 2 0 0 2 2 2 0 PglD N-terminal domain DUF1805 PF08827.11 CCD22831.1 - 0.15 12.4 0.0 0.61 10.4 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) YvbH_ext PF11724.8 CCD22831.1 - 5.5 7.4 7.8 1.6 9.1 0.4 3.2 3 0 0 3 3 2 0 YvbH-like oligomerisation region Inv-AAD PF18785.1 CCD22832.1 - 1e-38 132.1 0.1 2.3e-38 131.0 0.1 1.6 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase PseudoU_synth_2 PF00849.22 CCD22832.1 - 3e-34 118.4 0.9 7e-34 117.2 0.0 2.0 2 0 0 2 2 2 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.23 CCD22832.1 - 5.6e-18 64.7 0.1 1.5e-17 63.3 0.0 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCD22832.1 - 0.00013 21.8 0.0 0.00028 20.6 0.0 1.6 1 0 0 1 1 1 1 MafB19-like deaminase PQQ PF01011.21 CCD22832.1 - 0.00042 20.1 0.1 0.00098 18.9 0.1 1.7 1 0 0 1 1 1 1 PQQ enzyme repeat Metallophos PF00149.28 CCD22833.1 - 3.4e-38 132.2 0.1 4.4e-38 131.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CCD22833.1 - 0.00079 19.8 0.3 0.0017 18.7 0.3 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 CCD22833.1 - 0.091 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain PRP38 PF03371.15 CCD22834.1 - 2.5e-49 167.5 1.4 3.1e-49 167.2 1.4 1.0 1 0 0 1 1 1 1 PRP38 family DUF3143 PF11341.8 CCD22834.1 - 0.095 13.1 0.7 0.28 11.6 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3143) Mitoc_mL59 PF18126.1 CCD22835.1 - 1.9e-28 99.3 0.1 2.5e-28 99.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Prefoldin PF02996.17 CCD22836.1 - 1.3e-37 128.3 1.1 1.9e-37 127.8 1.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Pox_A_type_inc PF04508.12 CCD22836.1 - 0.00075 19.2 1.0 0.041 13.8 0.0 3.0 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat Prefoldin_2 PF01920.20 CCD22836.1 - 0.002 18.0 3.3 0.0046 16.9 0.2 2.3 1 1 0 2 2 2 1 Prefoldin subunit DUF1664 PF07889.12 CCD22836.1 - 0.23 11.5 1.2 1.3 9.1 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PRKG1_interact PF15898.5 CCD22836.1 - 0.32 11.9 4.1 10 7.1 0.2 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TMPIT PF07851.13 CCD22836.1 - 1.1 8.4 5.0 2 7.6 0.9 2.1 2 0 0 2 2 2 0 TMPIT-like protein XhlA PF10779.9 CCD22836.1 - 8.6 6.6 7.1 7.4 6.9 0.4 2.8 3 0 0 3 3 3 0 Haemolysin XhlA SUN PF03856.13 CCD22837.1 - 5.6e-81 271.6 18.5 7.1e-81 271.3 18.5 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Haem_degrading PF03928.14 CCD22838.1 - 2e-29 102.0 0.0 2.5e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading NatB_MDM20 PF09797.9 CCD22840.1 - 3.9e-45 154.4 6.9 2.9e-43 148.3 6.9 2.4 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit DUF1801 PF08818.11 CCD22840.1 - 0.0095 16.4 0.4 0.071 13.6 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DU1801) FKBP26_C PF18046.1 CCD22840.1 - 0.011 15.8 1.1 6.1 7.0 0.1 3.6 3 0 0 3 3 3 0 FKBP26_C-terminal Peptidase_S10 PF00450.22 CCD22841.1 - 1.2e-123 413.7 0.0 1.4e-123 413.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Mob_Pre PF01076.19 CCD22841.1 - 0.13 12.1 0.6 0.2 11.5 0.6 1.2 1 0 0 1 1 1 0 Plasmid recombination enzyme Crisp PF08562.10 CCD22841.1 - 0.46 11.1 0.0 0.46 11.1 0.0 2.1 2 0 0 2 2 2 0 Crisp RasGAP PF00616.19 CCD22842.1 - 8e-22 78.0 4.6 2.2e-14 53.7 0.2 3.3 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase Bmt2 PF11968.8 CCD22843.1 - 1.4e-77 260.5 0.0 2.1e-77 259.9 0.0 1.3 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 CCD22843.1 - 0.00096 19.0 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF3346 PF11826.8 CCD22843.1 - 0.057 13.2 0.5 0.12 12.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3346) Methyltransf_12 PF08242.12 CCD22843.1 - 0.064 14.0 0.0 0.14 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CCD22843.1 - 0.18 12.4 0.0 0.33 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.29 CCD22844.1 - 4.6e-38 130.7 0.5 1.1e-37 129.5 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD22844.1 - 3.1e-30 104.8 0.8 1.6e-26 92.8 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain UCR_UQCRX_QCR9 PF05365.12 CCD22844.1 - 0.094 12.7 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF2052 PF09747.9 CCD22844.1 - 0.33 11.1 20.2 0.027 14.6 3.6 2.6 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Ribosomal_60s PF00428.19 CCD22844.1 - 7.3 7.3 12.4 21 5.8 12.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein eRF1_2 PF03464.15 CCD22845.1 - 8.6e-46 155.5 0.1 1.7e-45 154.6 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CCD22845.1 - 2.3e-38 131.2 0.2 4.7e-38 130.1 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CCD22845.1 - 2.7e-20 72.7 0.0 4.8e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 CCD22845.1 - 1.9e-10 41.1 0.1 3e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 CCD22845.1 - 8.7e-09 35.8 0.1 1.9e-08 34.6 0.1 1.5 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 ATG19_autophagy PF12744.7 CCD22846.1 - 0.0037 16.5 0.0 0.0076 15.5 0.0 1.5 2 0 0 2 2 2 1 Autophagy protein Atg19, Atg8-binding HEPN_AbiV PF18728.1 CCD22846.1 - 0.075 13.2 1.5 1.9 8.6 1.2 2.1 2 0 0 2 2 2 0 AbiV ADH_N PF08240.12 CCD22847.1 - 2e-30 104.9 0.4 4.8e-30 103.7 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCD22847.1 - 9.3e-26 90.3 0.4 1.4e-25 89.8 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCD22847.1 - 6.7e-06 27.2 0.0 1.3e-05 26.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ribosomal_S9 PF00380.19 CCD22848.1 - 5.4e-41 139.9 0.1 8.2e-41 139.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Erythro-docking PF09277.11 CCD22848.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Erythronolide synthase, docking RibD_C PF01872.17 CCD22849.1 - 1.5e-40 139.1 0.0 1.7e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain RNA_pol_Rpb5_C PF01191.19 CCD22850.1 - 8.9e-33 112.0 1.5 9.8e-33 111.9 0.4 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CCD22850.1 - 2e-28 98.8 0.4 4.1e-28 97.8 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Sof1 PF04158.14 CCD22850.1 - 0.012 15.8 0.5 0.024 14.9 0.5 1.4 1 0 0 1 1 1 0 Sof1-like domain Mrr_cat PF04471.12 CCD22850.1 - 0.042 13.9 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease SH3_2 PF07653.17 CCD22850.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain MFAP1 PF06991.11 CCD22851.1 - 3.5e-11 43.4 7.5 3.5e-11 43.4 7.5 1.3 1 1 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing SR-25 PF10500.9 CCD22851.1 - 0.093 12.3 10.7 0.14 11.8 10.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Suc_Fer-like PF06999.12 CCD22852.1 - 1.6e-48 165.2 0.0 1.9e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Fungal_trans PF04082.18 CCD22853.1 - 1.5e-08 34.0 9.0 1.5e-08 34.0 9.0 3.4 4 0 0 4 4 4 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD22853.1 - 7.6e-08 32.4 13.5 1.8e-07 31.1 13.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fanconi_A PF03511.14 CCD22853.1 - 0.29 11.1 1.1 11 6.0 0.1 3.1 3 0 0 3 3 3 0 Fanconi anaemia group A protein Aldo_ket_red PF00248.21 CCD22854.1 - 3e-39 135.0 0.0 1.1e-37 129.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family IF2_N PF04760.15 CCD22854.1 - 0.054 13.3 0.2 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region PQ-loop PF04193.14 CCD22856.1 - 6.2e-38 128.4 13.6 8.6e-19 67.1 2.0 2.9 2 0 0 2 2 2 2 PQ loop repeat MMM1 PF10296.9 CCD22856.1 - 0.0041 16.2 0.0 0.0059 15.7 0.0 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 SARA PF11409.8 CCD22856.1 - 0.092 13.0 0.4 0.17 12.1 0.4 1.3 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) Vps52 PF04129.12 CCD22857.1 - 3.9e-136 454.8 26.5 7.4e-125 417.6 19.7 2.0 2 0 0 2 2 2 2 Vps52 / Sac2 family BUD22 PF09073.10 CCD22857.1 - 1.4 8.2 5.0 2.1 7.6 5.0 1.2 1 0 0 1 1 1 0 BUD22 TMEM174 PF15029.6 CCD22857.1 - 1.6 8.4 4.3 4 7.1 4.3 1.6 1 0 0 1 1 1 0 Transmembrane protein 174 FAM176 PF14851.6 CCD22857.1 - 5.4 6.7 7.0 0.5 10.0 1.3 2.1 1 1 1 2 2 2 0 FAM176 family YL1 PF05764.13 CCD22858.1 - 2.6e-46 158.7 53.1 2.6e-46 158.7 53.1 3.2 2 2 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 CCD22858.1 - 7.4e-13 48.0 0.6 1.3e-12 47.3 0.6 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Snf7 PF03357.21 CCD22859.1 - 5.3e-39 133.6 26.0 7e-39 133.2 26.0 1.1 1 0 0 1 1 1 1 Snf7 Fmp27_WPPW PF10359.9 CCD22859.1 - 0.0013 17.7 17.7 0.0038 16.2 17.9 1.7 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF5082 PF16888.5 CCD22859.1 - 0.0044 17.3 3.9 0.0044 17.3 3.9 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) CLZ PF16526.5 CCD22859.1 - 0.011 16.1 4.6 0.011 16.1 4.6 3.6 1 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Exonuc_VII_L PF02601.15 CCD22859.1 - 0.17 11.4 14.3 0.23 11.0 14.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3969 PF13108.6 CCD22859.1 - 0.17 11.9 3.9 0.39 10.7 3.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3969) KxDL PF10241.9 CCD22859.1 - 0.54 10.6 19.9 0.053 13.8 4.2 3.9 3 1 0 3 3 3 0 Uncharacterized conserved protein LMBR1 PF04791.16 CCD22859.1 - 0.64 8.9 9.4 0.74 8.7 9.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein YlqD PF11068.8 CCD22859.1 - 0.9 9.9 24.3 5.2 7.4 22.6 2.5 1 1 1 2 2 2 0 YlqD protein Fib_alpha PF08702.10 CCD22859.1 - 0.9 9.7 22.0 1.3 9.2 7.5 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2703 PF10865.8 CCD22859.1 - 1.1 9.5 4.6 2.7 8.2 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) SKA1 PF07160.12 CCD22859.1 - 1.1 9.1 18.6 1 9.1 16.1 1.9 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Serine_rich PF08824.10 CCD22859.1 - 1.5 8.8 18.3 0.051 13.6 9.1 2.3 1 1 1 2 2 2 0 Serine rich protein interaction domain Tropomyosin_1 PF12718.7 CCD22859.1 - 3.1 8.0 20.9 0.16 12.1 13.4 2.2 1 1 1 2 2 2 0 Tropomyosin like FliJ PF02050.16 CCD22859.1 - 4.1 7.7 23.4 0.07 13.3 13.4 2.6 2 1 2 4 4 3 0 Flagellar FliJ protein DUF1664 PF07889.12 CCD22859.1 - 6.7 6.8 17.8 0.48 10.5 5.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Corona_S2 PF01601.16 CCD22859.1 - 7.8 4.9 13.8 0.41 9.1 1.5 2.0 1 1 1 2 2 2 0 Coronavirus S2 glycoprotein FapA PF03961.13 CCD22859.1 - 9.6 4.7 14.2 6.1 5.3 11.3 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A DHBP_synthase PF00926.19 CCD22860.1 - 1.9e-84 282.0 0.0 2.1e-84 281.8 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase PLU-1 PF08429.11 CCD22860.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 PLU-1-like protein Ole-e-6 PF09253.10 CCD22861.1 - 0.053 13.5 1.1 0.11 12.5 1.1 1.5 1 0 0 1 1 1 0 Pollen allergen ole e 6 SLD5_C PF16922.5 CCD22862.1 - 9e-24 83.4 0.1 1.8e-23 82.5 0.1 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 CCD22862.1 - 1.2e-09 38.6 1.2 1.9e-07 31.5 0.8 2.5 2 0 0 2 2 2 2 GINS complex protein Vhr1 PF04001.13 CCD22862.1 - 0.035 14.4 0.9 0.092 13.1 0.4 2.0 2 0 0 2 2 2 0 Transcription factor Vhr1 Dimer_Tnp_hAT PF05699.14 CCD22863.1 - 0.021 14.6 0.1 0.021 14.6 0.1 2.4 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region CPL PF08144.11 CCD22864.1 - 2.5e-49 167.3 5.1 3.2e-47 160.5 0.1 4.0 3 2 0 3 3 3 1 CPL (NUC119) domain PUF PF00806.19 CCD22864.1 - 0.0036 16.9 5.4 12 5.9 0.0 5.8 6 0 0 6 6 6 2 Pumilio-family RNA binding repeat SAC3 PF12209.8 CCD22864.1 - 0.15 12.2 6.3 0.84 9.9 0.1 4.9 5 1 1 6 6 6 0 Leucine permease transcriptional regulator helical domain Nop14 PF04147.12 CCD22864.1 - 2.2 6.4 32.6 4 5.5 32.6 1.4 1 0 0 1 1 1 0 Nop14-like family Sugar_tr PF00083.24 CCD22865.1 - 8.4e-136 453.4 32.7 1.1e-135 453.0 32.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD22865.1 - 1.4e-31 109.7 38.0 1.2e-30 106.6 32.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCD22865.1 - 6e-06 25.0 6.9 6e-06 25.0 6.9 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 CCD22865.1 - 0.0028 16.1 0.6 0.0028 16.1 0.6 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector VQ PF05678.14 CCD22865.1 - 0.13 11.7 0.1 0.59 9.7 0.0 2.1 2 0 0 2 2 2 0 VQ motif Sec20 PF03908.13 CCD22866.1 - 1.6e-31 108.1 1.8 1.6e-31 108.1 1.8 2.5 3 0 0 3 3 3 1 Sec20 Mucin PF01456.17 CCD22866.1 - 0.0024 17.9 3.7 0.0024 17.9 3.7 2.6 2 1 0 2 2 2 1 Mucin-like glycoprotein SprA-related PF12118.8 CCD22866.1 - 1.9 7.5 19.6 3.5 6.7 19.6 1.3 1 0 0 1 1 1 0 SprA-related family 4_1_CTD PF05902.13 CCD22866.1 - 8.9 6.4 24.7 0.14 12.2 11.5 3.3 2 1 1 3 3 3 0 4.1 protein C-terminal domain (CTD) Ipi1_N PF12333.8 CCD22867.1 - 0.82 10.3 0.0 0.82 10.3 0.0 4.1 4 1 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Ribosomal_L18_c PF14204.6 CCD22868.1 - 0.0064 17.4 0.8 0.0064 17.4 0.8 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF5569 PF17729.1 CCD22869.1 - 0.0016 18.4 1.2 0.0018 18.2 1.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5569) Complex1_LYR PF05347.15 CCD22869.1 - 0.092 12.8 0.6 0.16 12.0 0.6 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) HlyIII PF03006.20 CCD22870.1 - 3.5e-51 174.1 23.7 4.2e-51 173.8 23.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related ERG4_ERG24 PF01222.17 CCD22871.1 - 1.1e-164 548.3 19.0 1.2e-164 548.2 19.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CCD22871.1 - 9.5e-07 28.6 1.0 9.5e-07 28.6 1.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) CTP_transf_1 PF01148.20 CCD22872.1 - 2.1e-76 257.2 19.9 2.8e-76 256.8 19.9 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Pro_3_hydrox_C PF05373.11 CCD22872.1 - 0.066 13.3 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Pkinase PF00069.25 CCD22873.1 - 5.8e-61 206.2 0.2 1e-59 202.1 0.2 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22873.1 - 3.1e-32 111.9 0.1 1e-30 106.9 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD22873.1 - 0.0031 16.9 0.5 0.038 13.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 CCD22873.1 - 0.041 14.6 7.7 0.3 11.8 7.7 2.6 1 1 0 1 1 1 0 Protein kinase C terminal domain ADH_zinc_N PF00107.26 CCD22874.1 - 1.6e-08 34.6 0.0 2.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase YchF-GTPase_C PF06071.13 CCD22875.1 - 1.4e-36 124.5 0.1 4.3e-36 123.0 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CCD22875.1 - 1.7e-16 60.3 0.0 1e-15 57.8 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 CCD22875.1 - 9.5e-05 22.4 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CCD22875.1 - 0.021 14.4 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B alpha-hel2 PF14456.6 CCD22875.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 SCO1-SenC PF02630.14 CCD22876.1 - 1.8e-46 157.4 0.0 2.8e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 CCD22876.1 - 0.00017 21.5 0.1 0.01 15.8 0.0 2.8 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CCD22876.1 - 0.001 19.4 0.6 0.029 14.7 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin-like Chitin_synth_1 PF01644.17 CCD22877.1 - 4.6e-70 234.8 0.6 8.2e-70 234.0 0.6 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 CCD22877.1 - 7.7e-24 84.2 3.8 7.8e-19 67.7 0.0 3.1 2 1 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 CCD22877.1 - 2.8e-20 72.1 1.4 8.5e-20 70.5 0.0 2.5 3 0 0 3 3 3 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 CCD22877.1 - 1.7e-08 34.6 0.4 1.7e-08 34.6 0.4 2.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CCD22877.1 - 7e-06 26.1 0.0 2.3e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 CCD22878.1 - 1.2e-287 954.8 0.1 1.2e-287 954.8 0.1 1.3 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 CCD22878.1 - 2.6e-12 47.0 1.9 1.1e-11 45.0 1.9 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CCD22878.1 - 3.8e-11 43.3 0.0 5.7e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CCD22878.1 - 0.003 17.4 0.0 0.068 13.0 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CCD22878.1 - 0.0034 16.9 0.0 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Macro PF01661.21 CCD22879.1 - 5.4e-26 91.0 0.0 6.6e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Macro domain DUF1768 PF08719.11 CCD22879.1 - 0.044 14.0 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) Transp_cyt_pur PF02133.15 CCD22880.1 - 1e-175 584.8 35.5 1.2e-175 584.6 35.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin GalKase_gal_bdg PF10509.9 CCD22881.1 - 1.8e-21 75.4 0.0 3.5e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 CCD22881.1 - 8e-17 61.2 1.0 1.3e-16 60.6 0.3 1.7 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF1748 PF08520.10 CCD22881.1 - 0.014 15.2 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) Aldose_epim PF01263.20 CCD22882.1 - 5.6e-78 262.3 0.4 7.4e-78 261.9 0.4 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase GDP_Man_Dehyd PF16363.5 CCD22882.1 - 1.3e-57 195.7 0.0 1.9e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CCD22882.1 - 2.1e-52 178.0 0.0 3.5e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CCD22882.1 - 3e-16 59.4 0.0 1.1e-14 54.3 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CCD22882.1 - 2.5e-14 53.0 0.0 5.2e-14 51.9 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CCD22882.1 - 7.6e-10 38.4 0.0 1.1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 CCD22882.1 - 1.4e-07 31.6 0.0 2.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 CCD22882.1 - 2.8e-06 26.9 0.0 4.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 CCD22882.1 - 5.6e-06 25.7 0.0 4.4e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CCD22882.1 - 0.00035 20.5 0.0 0.00057 19.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding AAA PF00004.29 CCD22883.1 - 1.2e-41 142.2 0.0 2e-41 141.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCD22883.1 - 1.2e-10 41.0 0.2 2.4e-10 40.0 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CCD22883.1 - 3.1e-08 33.4 0.0 5.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain DUF815 PF05673.13 CCD22883.1 - 5.3e-06 25.8 0.0 9e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CCD22883.1 - 8.9e-06 26.0 0.4 0.013 15.7 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 CCD22883.1 - 9.5e-06 25.8 0.0 2.6e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CCD22883.1 - 2.3e-05 24.4 0.1 9.5e-05 22.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCD22883.1 - 4.3e-05 24.0 0.1 0.0026 18.2 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CCD22883.1 - 0.00024 20.9 0.0 0.00053 19.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CCD22883.1 - 0.0028 17.9 0.3 0.0065 16.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CCD22883.1 - 0.0046 17.0 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCD22883.1 - 0.0085 16.6 0.5 0.022 15.3 0.0 2.0 3 0 0 3 3 1 1 AAA domain AAA_3 PF07726.11 CCD22883.1 - 0.011 15.6 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CCD22883.1 - 0.011 15.9 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CCD22883.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 CCD22883.1 - 0.015 14.5 0.0 0.038 13.2 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase PF06745.13 CCD22883.1 - 0.018 14.4 0.2 0.4 10.0 0.1 2.4 1 1 0 2 2 2 0 KaiC PhoH PF02562.16 CCD22883.1 - 0.02 14.4 0.4 0.39 10.2 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 CCD22883.1 - 0.029 14.8 0.0 0.071 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 CCD22883.1 - 0.032 14.2 0.6 0.27 11.1 0.0 2.5 3 0 0 3 3 2 0 NTPase Mg_chelatase PF01078.21 CCD22883.1 - 0.044 13.2 0.1 0.094 12.1 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 CCD22883.1 - 0.062 12.5 0.1 0.36 10.0 0.1 2.2 2 1 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 CCD22883.1 - 0.067 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 CCD22883.1 - 0.11 12.5 0.2 0.49 10.3 0.1 2.0 1 1 1 2 2 2 0 NACHT domain DUF2075 PF09848.9 CCD22883.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 CCD22883.1 - 0.13 11.8 0.1 0.37 10.3 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 CCD22883.1 - 0.14 11.7 2.3 0.44 10.1 0.4 2.4 2 1 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CCD22883.1 - 0.15 11.7 1.7 0.26 11.0 0.5 2.1 2 1 0 2 2 2 0 AAA domain PP2C PF00481.21 CCD22884.1 - 2.2e-67 227.4 0.2 1.4e-52 178.9 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Med2 PF11214.8 CCD22885.1 - 6.5e-35 119.3 15.0 6.5e-35 119.3 15.0 4.6 1 1 3 4 4 4 1 Mediator complex subunit 2 Utp14 PF04615.13 CCD22885.1 - 0.21 10.1 31.8 0.28 9.7 31.8 1.2 1 0 0 1 1 1 0 Utp14 protein SLC12 PF03522.15 CCD22885.1 - 2.6 6.9 36.4 0.086 11.9 24.2 2.1 2 0 0 2 2 2 0 Solute carrier family 12 Thiamine_BP PF01910.17 CCD22886.1 - 1.7e-28 98.3 0.1 2e-28 98.1 0.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Histone PF00125.24 CCD22887.1 - 2.9e-17 63.3 7.1 4e-17 62.8 7.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCD22887.1 - 1.2e-05 25.5 0.1 2.3e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CCD22887.1 - 0.0021 18.5 0.0 0.0042 17.6 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 CCD22887.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 CENP-W protein Dicty_REP PF05086.12 CCD22887.1 - 1.6 6.6 8.8 1.7 6.5 8.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Histone_H2A_C PF16211.5 CCD22888.1 - 3.7e-21 74.6 1.1 6.1e-21 73.9 1.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CCD22888.1 - 1.7e-17 64.0 0.0 2.3e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCD22888.1 - 7.7e-06 26.1 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LcrG PF07216.12 CCD22888.1 - 0.043 13.7 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 LcrG protein DUF155 PF02582.14 CCD22889.1 - 3.1e-57 193.5 1.9 5.5e-57 192.7 1.9 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 CCD22889.1 - 0.019 15.4 0.1 0.12 12.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 HMG_box PF00505.19 CCD22890.1 - 1.5e-12 47.7 0.0 4.9e-12 46.1 0.0 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCD22890.1 - 3.2e-10 40.4 0.0 9.4e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 HMG-box domain MCC-bdg_PDZ PF10506.9 CCD22890.1 - 0.083 12.9 0.4 0.21 11.7 0.4 1.7 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome F-box-like PF12937.7 CCD22891.1 - 1.1e-06 28.5 2.6 1.2e-06 28.2 0.6 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CCD22891.1 - 0.00021 21.1 0.9 0.00021 21.1 0.9 3.1 3 0 0 3 3 3 1 F-box domain CdiI PF07262.11 CCD22891.1 - 0.025 14.3 2.7 0.1 12.3 2.7 2.1 1 0 0 1 1 1 0 CDI immunity protein Bac_rhodopsin PF01036.18 CCD22892.1 - 1.9e-24 86.5 9.9 2.3e-24 86.3 9.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF3309 PF11752.8 CCD22892.1 - 0.12 12.5 2.0 0.16 12.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) DUF5592 PF17332.2 CCD22892.1 - 0.72 10.4 6.6 0.78 10.3 2.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5592) Wzy_C PF04932.15 CCD22892.1 - 1.6 8.3 7.3 0.26 10.9 0.4 2.1 1 1 0 2 2 2 0 O-Antigen ligase DUF1772 PF08592.11 CCD22892.1 - 3.5 8.0 11.9 0.74 10.1 1.5 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) Cellulase PF00150.18 CCD22893.1 - 1.4e-09 37.8 2.6 1.4e-09 37.8 2.6 1.9 2 1 1 3 3 3 1 Cellulase (glycosyl hydrolase family 5) Wtap PF17098.5 CCD22894.1 - 0.0024 17.8 7.2 0.0024 17.8 7.2 2.2 1 1 1 2 2 2 1 WTAP/Mum2p family Lzipper-MIP1 PF14389.6 CCD22894.1 - 0.018 15.3 3.1 0.099 13.0 3.1 2.2 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 XLF PF09302.11 CCD22894.1 - 0.028 14.6 7.7 0.063 13.4 0.5 2.5 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Stk19 PF10494.9 CCD22894.1 - 0.031 13.9 0.7 0.063 12.9 0.7 1.4 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 DUF3837 PF12939.7 CCD22894.1 - 0.14 12.6 5.9 4 7.9 0.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3837) Tropomyosin_1 PF12718.7 CCD22894.1 - 0.2 11.8 9.5 0.52 10.5 9.5 1.8 1 1 0 1 1 1 0 Tropomyosin like SPATA1_C PF15743.5 CCD22894.1 - 0.96 9.5 11.0 0.11 12.5 5.1 2.2 2 1 1 3 3 3 0 Spermatogenesis-associated C-terminus Med30 PF11315.8 CCD22894.1 - 1.2 9.3 9.8 0.12 12.6 4.7 2.0 2 0 0 2 2 2 0 Mediator complex subunit 30 UCH PF00443.29 CCD22895.1 - 2.9e-42 145.0 0.4 5.2e-42 144.1 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CCD22895.1 - 1.9e-19 69.7 5.4 1.9e-19 69.7 5.4 2.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CCD22895.1 - 1.2e-17 64.5 0.8 1.2e-17 64.5 0.8 2.9 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 CCD22895.1 - 6.3e-12 45.1 10.3 1.1e-11 44.2 3.2 2.8 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 CCD22895.1 - 6.2e-10 38.8 0.0 1.6e-07 31.1 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ORC2 PF04084.14 CCD22897.1 - 3.8e-106 354.7 0.3 6.6e-106 354.0 0.3 1.4 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.19 CCD22897.1 - 0.022 14.6 18.6 0.66 10.0 4.3 3.4 2 0 0 2 2 2 0 AT hook motif FtsJ PF01728.19 CCD22898.1 - 1.4e-66 224.0 0.1 1.9e-66 223.6 0.1 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 CCD22898.1 - 0.067 13.0 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 CCD22898.1 - 0.1 12.2 0.1 0.23 11.0 0.1 1.7 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F zf-RING_2 PF13639.6 CCD22899.1 - 2.6e-11 43.7 7.5 4.8e-11 42.8 7.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CCD22899.1 - 2.5e-08 34.1 8.0 1.2e-07 31.9 8.0 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CCD22899.1 - 8.2e-06 25.6 7.9 1.8e-05 24.5 7.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CCD22899.1 - 2e-05 24.5 2.6 2.5e-05 24.2 1.8 1.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CCD22899.1 - 2.6e-05 24.0 6.7 2.6e-05 24.0 6.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCD22899.1 - 8.3e-05 22.5 2.8 8.3e-05 22.5 2.8 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 CCD22899.1 - 0.0002 21.0 5.8 0.00048 19.8 5.8 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 CCD22899.1 - 0.00043 20.1 5.1 0.0014 18.5 5.2 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CCD22899.1 - 0.00058 20.0 8.1 0.0014 18.8 5.4 2.6 2 1 0 2 2 2 1 FANCL C-terminal domain zf-RING_5 PF14634.6 CCD22899.1 - 0.006 16.5 5.0 0.006 16.5 5.0 1.7 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CCD22899.1 - 0.066 13.1 7.3 0.24 11.3 7.4 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CCD22899.1 - 0.25 11.5 7.9 0.95 9.7 8.0 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 CCD22899.1 - 0.26 11.0 6.6 0.87 9.3 6.6 1.9 1 1 0 1 1 1 0 P-11 zinc finger zf-C3HC4_3 PF13920.6 CCD22900.1 - 3.8 7.5 13.0 8.5 6.3 5.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) KIAA1430 PF13879.6 CCD22900.1 - 9.1 7.1 12.5 0.13 13.0 1.0 2.5 2 0 0 2 2 2 0 KIAA1430 homologue zf-H2C2_2 PF13465.6 CCD22901.1 - 0.00011 22.5 3.7 0.00011 22.5 3.7 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 CCD22901.1 - 0.003 17.9 20.0 0.01 16.2 4.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF3389 PF11869.8 CCD22901.1 - 0.068 13.4 0.1 3.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3389) zf-C2H2_4 PF13894.6 CCD22901.1 - 0.41 11.6 17.8 1.2 10.2 2.0 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 CCD22901.1 - 4.1 7.9 9.8 2.1 8.9 1.0 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type SRP1_TIP1 PF00660.17 CCD22902.1 - 2.6e-35 120.4 0.4 2.6e-35 120.4 0.4 1.6 2 0 0 2 2 2 1 Seripauperin and TIP1 family PIR PF00399.19 CCD22902.1 - 3.1e-08 33.0 0.9 1.7e-07 30.6 0.9 2.5 1 0 0 1 1 1 1 Yeast PIR protein repeat Hid1 PF12722.7 CCD22902.1 - 0.12 10.5 1.3 0.14 10.2 1.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RIFIN PF02009.16 CCD22902.1 - 0.72 9.7 3.9 0.9 9.4 3.9 1.2 1 0 0 1 1 1 0 Rifin FAM199X PF15814.5 CCD22902.1 - 2.4 7.1 17.9 3.5 6.6 17.9 1.3 1 0 0 1 1 1 0 Protein family FAM199X MCLC PF05934.11 CCD22902.1 - 8.4 5.0 7.2 10 4.7 7.2 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) AA_permease PF00324.21 CCD22903.1 - 2.4e-131 438.6 33.3 2.9e-131 438.4 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD22903.1 - 2.8e-38 131.9 31.7 3.8e-38 131.4 31.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCD22904.1 - 8e-128 427.0 33.0 1e-127 426.7 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD22904.1 - 4.6e-38 131.1 34.1 5.7e-38 130.9 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 CCD22904.1 - 0.0028 16.5 22.0 0.0064 15.4 15.6 2.5 2 0 0 2 2 2 2 Spore germination protein Pet100 PF09803.9 CCD22904.1 - 0.33 11.5 3.1 0.22 12.1 0.7 1.9 2 0 0 2 2 2 0 Pet100 SNF2_N PF00176.23 CCD22905.1 - 6.1e-61 206.1 0.0 1.1e-60 205.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCD22905.1 - 2.9e-15 56.6 0.0 7.3e-14 52.1 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD22905.1 - 3e-13 50.1 0.4 7.6e-12 45.6 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CCD22905.1 - 8.8e-07 28.4 6.6 3.4e-06 26.4 2.1 3.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CCD22905.1 - 1e-05 25.4 0.0 2.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Fer4_14 PF13394.6 CCD22905.1 - 0.045 13.9 0.1 0.23 11.6 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S single cluster domain Peptidase_M28 PF04389.17 CCD22906.1 - 3.1e-38 131.5 0.0 1.5e-37 129.3 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M42 PF05343.14 CCD22906.1 - 0.0015 17.6 0.0 0.0036 16.4 0.0 1.6 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 CCD22906.1 - 0.0018 18.0 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4451 PF14616.6 CCD22907.1 - 4.1e-06 27.0 4.1 5.7e-06 26.5 0.1 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4451) DUF1233 PF06806.12 CCD22907.1 - 0.097 12.3 0.0 0.32 10.6 0.0 1.8 1 0 0 1 1 1 0 Putative excisionase (DUF1233) zf-C2H2 PF00096.26 CCD22908.1 - 9.1e-10 38.5 15.0 2e-05 24.8 3.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD22908.1 - 3.8e-07 30.4 11.0 0.00061 20.4 2.0 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCD22908.1 - 1.7e-06 28.2 0.3 1.7e-06 28.2 0.3 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 CCD22908.1 - 9.5e-06 25.8 5.9 0.00096 19.5 1.4 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCD22908.1 - 0.00055 20.2 5.6 0.0022 18.2 0.8 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CCD22908.1 - 0.049 13.6 1.5 0.049 13.6 1.5 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CCD22908.1 - 0.17 12.2 3.7 0.96 9.8 3.5 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 CCD22908.1 - 0.43 10.9 3.2 0.36 11.2 0.4 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 CCD22908.1 - 2.6 7.9 8.3 1.1 9.1 2.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Dfp1_Him1_M PF08630.10 CCD22909.1 - 1.1e-13 51.5 1.0 6.3e-10 39.4 0.2 2.8 1 1 1 2 2 2 2 Dfp1/Him1, central region SLM4 PF16818.5 CCD22910.1 - 2.5e-71 238.9 2.5 3.5e-71 238.4 2.5 1.2 1 0 0 1 1 1 1 Protein SLM4 UQ_con PF00179.26 CCD22911.1 - 1.4e-41 141.5 0.2 2.1e-41 140.9 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCD22911.1 - 0.00045 19.9 0.0 0.0012 18.5 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B FAM131 PF15010.6 CCD22911.1 - 0.032 14.1 0.3 0.039 13.9 0.3 1.1 1 0 0 1 1 1 0 Putative cell signalling Recep_L_domain PF01030.24 CCD22912.1 - 8.1e-07 29.2 6.4 0.3 11.2 0.3 4.7 1 1 2 3 3 3 3 Receptor L domain LRR_9 PF14580.6 CCD22912.1 - 0.00085 18.9 1.4 0.0038 16.7 0.2 2.2 1 1 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 CCD22912.1 - 0.53 10.8 11.7 8.1 7.0 0.1 4.6 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) PCI PF01399.27 CCD22913.1 - 1.2e-05 25.8 5.2 0.00013 22.4 0.0 3.2 3 0 0 3 3 3 2 PCI domain AAA PF00004.29 CCD22914.1 - 2.3e-52 176.9 0.0 1.4e-37 129.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 CCD22914.1 - 7.2e-10 38.5 0.6 3.4e-09 36.4 0.1 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_lid_3 PF17862.1 CCD22914.1 - 1.1e-09 38.0 0.1 7.2e-09 35.3 0.1 2.3 1 1 1 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 CCD22914.1 - 1.3e-09 38.4 0.1 0.0005 20.4 0.1 3.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CCD22914.1 - 2.8e-09 37.6 0.1 0.0011 19.4 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 CCD22914.1 - 1e-08 34.8 0.0 0.00059 19.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 CCD22914.1 - 1.5e-07 31.0 0.1 0.0019 17.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CCD22914.1 - 2.4e-07 30.8 0.0 0.0027 17.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CCD22914.1 - 4.8e-07 29.7 0.4 0.044 13.5 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CCD22914.1 - 8.7e-07 29.2 0.0 0.03 14.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain CDC48_N PF02359.18 CCD22914.1 - 1.4e-06 28.4 0.0 5.1e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain PhoH PF02562.16 CCD22914.1 - 4.6e-06 26.2 0.0 0.0053 16.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.6 CCD22914.1 - 5.2e-06 26.3 0.1 0.1 12.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CCD22914.1 - 6.5e-06 26.0 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 CCD22914.1 - 1.6e-05 25.5 0.0 0.38 11.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 CCD22914.1 - 1.8e-05 25.0 0.0 0.14 12.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_2 PF07724.14 CCD22914.1 - 2e-05 24.8 0.0 0.0023 18.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 CCD22914.1 - 3.1e-05 24.0 1.8 0.059 13.3 0.0 3.5 4 0 0 4 4 3 1 NACHT domain AAA_11 PF13086.6 CCD22914.1 - 3.4e-05 23.8 0.2 0.39 10.5 0.0 2.7 2 1 0 3 3 3 2 AAA domain ABC_tran PF00005.27 CCD22914.1 - 3.6e-05 24.3 0.2 0.059 13.9 0.1 2.7 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 CCD22914.1 - 0.00012 21.9 0.0 0.3 10.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 CCD22914.1 - 0.00012 21.3 0.0 0.078 12.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.9 CCD22914.1 - 0.00029 20.2 0.0 0.74 9.0 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 CCD22914.1 - 0.00051 20.6 0.6 0.64 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CCD22914.1 - 0.00051 19.6 0.0 0.07 12.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 CCD22914.1 - 0.0009 19.0 0.1 0.88 9.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 CCD22914.1 - 0.001 19.1 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 CCD22914.1 - 0.0012 18.8 0.0 0.58 10.2 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 CCD22914.1 - 0.0013 18.1 0.5 0.28 10.5 0.1 2.6 2 1 0 2 2 2 1 KaiC AAA_3 PF07726.11 CCD22914.1 - 0.0016 18.3 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CCD22914.1 - 0.0019 17.8 0.5 2.3 7.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain TniB PF05621.11 CCD22914.1 - 0.0021 17.5 0.2 4.3 6.7 0.1 3.4 3 1 0 3 3 2 0 Bacterial TniB protein AAA_19 PF13245.6 CCD22914.1 - 0.0028 18.0 0.1 1.2 9.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CCD22914.1 - 0.0028 18.1 0.0 0.62 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 CCD22914.1 - 0.0045 16.8 0.0 1.5 8.6 0.0 2.8 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_28 PF13521.6 CCD22914.1 - 0.0052 17.1 0.0 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CCD22914.1 - 0.0064 16.4 0.2 2.5 8.0 0.0 3.1 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 CCD22914.1 - 0.007 15.5 0.0 3.1 6.8 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 CCD22914.1 - 0.021 14.1 0.0 0.64 9.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.6 CCD22914.1 - 0.03 14.0 0.2 2.5 7.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 CCD22914.1 - 0.051 13.5 0.1 7.2 6.5 0.1 2.6 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 CCD22914.1 - 0.055 13.4 0.1 14 5.6 0.0 2.8 2 1 1 3 3 2 0 Rad17 P-loop domain T2SSE PF00437.20 CCD22914.1 - 0.059 12.4 0.0 8.7 5.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein CPT PF07931.12 CCD22914.1 - 0.083 12.7 0.3 7.7 6.3 0.0 2.9 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein Vps4_C PF09336.10 CCD22914.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain DEAD PF00270.29 CCD22914.1 - 0.11 12.3 0.3 44 3.8 0.0 3.8 3 1 1 4 4 4 0 DEAD/DEAH box helicase Sigma54_activ_2 PF14532.6 CCD22914.1 - 0.14 12.3 0.0 28 4.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain cobW PF02492.19 CCD22914.1 - 0.14 11.7 0.3 3.5 7.2 0.0 2.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Bromodomain PF00439.25 CCD22916.1 - 3.3e-15 55.9 0.4 1.3e-14 54.0 0.4 2.1 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 CCD22916.1 - 1.2e-05 25.2 0.0 5e-05 23.2 0.0 2.1 1 0 0 1 1 1 1 Bromodomain associated CBF PF03914.17 CCD22917.1 - 2.6e-48 164.3 0.1 2.6e-48 164.3 0.1 3.6 4 1 0 4 4 4 1 CBF/Mak21 family TEA PF01285.18 CCD22918.1 - 2.5e-25 88.3 0.3 1e-24 86.3 0.3 2.2 1 0 0 1 1 1 1 TEA/ATTS domain FTHFS PF01268.19 CCD22919.1 - 1.4e-251 835.6 0.2 2e-251 835.0 0.2 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CCD22919.1 - 1e-67 226.4 0.3 1e-67 226.4 0.3 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CCD22919.1 - 5.9e-35 120.0 0.5 1.7e-34 118.6 0.5 1.9 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain PBP-Tp47_a PF14889.6 CCD22919.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a 2-ph_phosp PF04029.14 CCD22919.1 - 0.16 11.1 0.0 0.35 10.0 0.0 1.5 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase Ribosomal_L19e PF01280.20 CCD22920.1 - 3e-58 196.0 9.3 3e-58 196.0 9.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e NIBRIN_BRCT_II PF16508.5 CCD22920.1 - 0.092 13.1 1.4 0.6 10.5 0.1 2.1 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein TilS PF09179.11 CCD22920.1 - 0.54 10.8 6.3 25 5.5 6.5 2.6 2 1 0 2 2 2 0 TilS substrate binding domain Mito_carr PF00153.27 CCD22921.1 - 2.1e-69 229.5 7.5 2.7e-25 88.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 CCD22921.1 - 0.12 11.5 0.1 0.37 9.9 0.1 1.7 2 0 0 2 2 2 0 Fuseless KH_1 PF00013.29 CCD22922.1 - 1.6e-34 117.5 6.4 4.2e-11 42.5 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CCD22922.1 - 7.5e-09 35.3 5.0 0.047 13.5 0.1 4.0 4 0 0 4 4 4 3 KH domain KH_4 PF13083.6 CCD22922.1 - 7.3e-08 32.2 0.1 0.022 14.6 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 CCD22922.1 - 1.9e-06 27.8 7.6 0.011 15.9 0.1 4.1 3 1 0 3 3 3 2 NusA-like KH domain SLS PF14611.6 CCD22922.1 - 0.0028 17.5 7.0 0.11 12.3 1.0 2.9 2 1 1 3 3 3 2 Mitochondrial inner-membrane-bound regulator Anoctamin PF04547.12 CCD22924.1 - 1.1e-32 113.5 37.0 2.6e-32 112.2 37.0 1.5 1 1 0 1 1 1 1 Calcium-activated chloride channel Mucin PF01456.17 CCD22924.1 - 2.7 8.0 18.3 6.5 6.7 15.5 2.8 2 0 0 2 2 2 0 Mucin-like glycoprotein Ala_racemase_N PF01168.20 CCD22925.1 - 1.6e-18 67.2 0.0 2e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain FAD_binding_1 PF00667.20 CCD22926.1 - 1.3e-29 103.4 0.0 2.9e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CCD22926.1 - 1.9e-27 96.3 0.0 3.3e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CCD22926.1 - 9.9e-11 42.3 0.0 2.3e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain MFS_1 PF07690.16 CCD22927.1 - 4.5e-34 117.9 35.7 4.5e-34 117.9 35.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CCD22927.1 - 1e-05 24.2 6.1 1.7e-05 23.5 6.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 CCD22927.1 - 0.038 12.3 21.7 0.0052 15.1 11.7 3.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PCNA_N PF00705.18 CCD22928.1 - 1.6e-54 183.0 1.6 2.7e-54 182.3 1.6 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CCD22928.1 - 2.1e-49 166.9 0.1 4.8e-49 165.8 0.1 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 CCD22928.1 - 6.7e-06 25.4 1.4 5.2e-05 22.4 1.4 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 CCD22928.1 - 0.0059 16.1 0.1 0.0074 15.8 0.1 1.2 1 0 0 1 1 1 1 Rad9 FOP_dimer PF09398.10 CCD22928.1 - 0.013 15.8 0.1 0.032 14.5 0.1 1.7 1 0 0 1 1 1 0 FOP N terminal dimerisation domain zf-Tim10_DDP PF02953.15 CCD22929.1 - 6e-15 54.6 2.3 7.5e-15 54.3 2.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TTL PF03133.15 CCD22930.1 - 2.7e-79 266.4 5.6 4e-79 265.8 4.6 1.6 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family SurE PF01975.17 CCD22930.1 - 1.7e-43 148.7 0.0 3e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 CCD22930.1 - 0.00049 19.4 0.1 0.02 14.1 0.1 2.3 2 0 0 2 2 2 1 YheC/D like ATP-grasp Herpes_BLLF1 PF05109.13 CCD22930.1 - 0.086 10.8 0.1 0.12 10.3 0.1 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) ATPgrasp_ST PF14397.6 CCD22930.1 - 0.1 11.8 0.0 4.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp RXT2_N PF08595.11 CCD22931.1 - 2e-41 141.6 1.4 2e-41 141.6 1.4 2.4 2 0 0 2 2 2 1 RXT2-like, N-terminal RE_HindVP PF09519.10 CCD22931.1 - 0.037 13.1 0.1 0.06 12.4 0.1 1.3 1 0 0 1 1 1 0 HindVP restriction endonuclease RPT PF13446.6 CCD22931.1 - 0.28 11.1 3.0 5.2 7.1 0.1 3.6 3 0 0 3 3 3 0 A repeated domain in UCH-protein Lin-8 PF03353.15 CCD22931.1 - 3.7 7.0 13.4 1.4 8.4 10.0 2.0 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist DUF2547 PF10818.8 CCD22931.1 - 5.2 8.1 6.6 5.5 8.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2547) 4HBT_2 PF13279.6 CCD22932.1 - 3.9e-06 27.4 0.0 5.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Pkinase PF00069.25 CCD22933.1 - 1.7e-24 86.7 0.0 3.6e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD22933.1 - 2.4e-09 36.9 0.0 1.3e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT PF02985.22 CCD22933.1 - 0.0008 19.5 1.5 18 5.9 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat ERCC4 PF02732.15 CCD22934.1 - 6.8e-15 55.6 2.0 1.8e-14 54.2 2.0 1.7 1 0 0 1 1 1 1 ERCC4 domain PriX PF18689.1 CCD22934.1 - 0.0062 16.9 0.2 0.025 14.9 0.2 2.1 1 0 0 1 1 1 1 Primase X MAGI_u1 PF16663.5 CCD22934.1 - 0.029 14.5 0.1 0.15 12.1 0.1 2.3 1 0 0 1 1 1 0 Unstructured region on MAGI DUF2187 PF09953.9 CCD22934.1 - 0.83 9.7 3.8 33 4.6 0.3 3.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2187) CENP-H PF05837.12 CCD22934.1 - 2.1 8.8 0.0 2.1 8.8 0.0 3.5 4 0 0 4 4 4 0 Centromere protein H (CENP-H) Fes1 PF08609.10 CCD22935.1 - 7.9e-21 74.8 0.4 7.9e-21 74.8 0.4 3.3 3 1 0 3 3 3 1 Nucleotide exchange factor Fes1 IBN_N PF03810.19 CCD22935.1 - 0.00072 19.4 2.1 0.028 14.3 0.4 3.5 2 1 2 4 4 4 1 Importin-beta N-terminal domain CDC14 PF08045.11 CCD22935.1 - 0.0014 17.8 0.4 0.004 16.3 0.4 1.8 1 0 0 1 1 1 1 Cell division control protein 14, SIN component HEAT_2 PF13646.6 CCD22935.1 - 0.0018 18.7 0.2 0.23 11.9 0.0 3.2 2 1 2 4 4 4 2 HEAT repeats DUF3361 PF11841.8 CCD22935.1 - 0.0018 18.2 1.6 0.0018 18.2 1.6 2.5 1 1 2 3 3 3 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 CCD22935.1 - 0.0041 17.2 5.0 0.014 15.5 1.2 2.6 1 1 2 3 3 3 3 V-ATPase subunit H DUF4704 PF15787.5 CCD22935.1 - 0.0094 15.2 3.6 0.02 14.1 0.4 2.5 1 1 2 3 3 3 1 Domain of unknown function (DUF4704) Atx10homo_assoc PF09759.9 CCD22935.1 - 0.014 15.4 1.3 0.014 15.4 1.3 2.4 2 1 2 4 4 3 0 Spinocerebellar ataxia type 10 protein domain Tti2 PF10521.9 CCD22935.1 - 0.019 14.5 2.1 3 7.3 0.1 2.6 1 1 2 3 3 3 0 Tti2 family UME PF08064.13 CCD22935.1 - 0.059 13.3 0.2 0.67 9.9 0.1 2.5 2 2 0 2 2 2 0 UME (NUC010) domain HEAT_EZ PF13513.6 CCD22935.1 - 0.068 13.7 0.5 1.7 9.2 0.5 2.9 1 1 0 1 1 1 0 HEAT-like repeat HEAT PF02985.22 CCD22935.1 - 0.091 13.1 0.1 4.3 7.9 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat Arm PF00514.23 CCD22935.1 - 0.15 12.1 1.4 8.9 6.5 0.1 3.5 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat Exo84_C PF16528.5 CCD22936.1 - 1.7e-67 227.2 10.3 1.7e-67 227.2 10.3 2.3 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CCD22936.1 - 2.7e-10 40.2 1.9 2.7e-10 40.2 1.9 3.4 3 1 1 4 4 4 1 Vps51/Vps67 COG2 PF06148.11 CCD22936.1 - 3.8e-05 23.8 1.2 3.8e-05 23.8 1.2 2.9 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 CCD22936.1 - 0.082 13.1 13.2 0.044 13.9 0.9 3.6 3 1 1 4 4 4 0 Golgi transport complex subunit 5 CHAD PF05235.14 CCD22936.1 - 0.18 11.7 0.3 0.63 10.0 0.3 1.9 1 1 0 1 1 1 0 CHAD domain XH PF03469.14 CCD22936.1 - 0.69 9.8 4.6 1.1 9.2 0.8 2.5 2 0 0 2 2 2 0 XH domain Cob_adeno_trans PF01923.18 CCD22936.1 - 1.3 9.2 4.4 3.3 7.8 0.1 3.1 3 1 0 3 3 3 0 Cobalamin adenosyltransferase HSCB_C PF07743.13 CCD22936.1 - 3.7 8.1 10.8 12 6.5 0.1 3.9 3 2 1 4 4 4 0 HSCB C-terminal oligomerisation domain SIT PF15330.6 CCD22936.1 - 9.2 6.7 8.7 2.4 8.6 4.2 2.2 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT WD40 PF00400.32 CCD22937.1 - 1.7e-21 76.1 13.5 1.4e-06 28.9 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD22937.1 - 1e-13 51.3 7.6 3.9e-05 23.9 0.1 6.7 2 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCD22937.1 - 3.9e-06 26.4 7.6 0.0051 16.2 1.0 3.7 3 1 0 4 4 4 2 WD40-like domain LisH PF08513.11 CCD22937.1 - 1e-05 25.3 0.2 2.8e-05 23.9 0.2 1.8 1 0 0 1 1 1 1 LisH Spt20 PF12090.8 CCD22937.1 - 0.00027 20.6 6.9 0.00027 20.6 6.9 2.0 2 0 0 2 2 2 1 Spt20 family eIF2A PF08662.11 CCD22937.1 - 0.00053 19.9 5.8 0.19 11.6 0.2 4.7 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 CCD22937.1 - 0.17 11.1 0.0 0.17 11.1 0.0 3.2 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Androgen_recep PF02166.16 CCD22937.1 - 4.8 5.9 6.6 7.7 5.2 6.6 1.2 1 0 0 1 1 1 0 Androgen receptor Presenilin PF01080.17 CCD22937.1 - 7.6 5.2 9.2 12 4.6 9.2 1.2 1 0 0 1 1 1 0 Presenilin zf-C2H2_6 PF13912.6 CCD22938.1 - 0.016 15.2 3.0 0.32 11.1 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CCD22938.1 - 0.067 13.7 0.8 0.067 13.7 0.8 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Peptidase_C5 PF00770.18 CCD22938.1 - 0.35 10.5 3.5 0.42 10.3 3.5 1.1 1 0 0 1 1 1 0 Adenovirus endoprotease Mito_carr PF00153.27 CCD22939.1 - 2.3e-58 194.1 1.3 1.3e-20 73.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Vac_ImportDeg PF09783.9 CCD22940.1 - 3.8e-53 179.6 4.0 5.9e-53 179.0 4.0 1.3 1 0 0 1 1 1 1 Vacuolar import and degradation protein Pho88 PF10032.9 CCD22941.1 - 2.8e-66 222.2 2.7 3.3e-66 222.0 2.7 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Toxin_R_bind_C PF07951.12 CCD22941.1 - 0.27 10.9 1.9 0.36 10.5 1.9 1.3 1 1 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding Fe-S_biosyn PF01521.20 CCD22942.1 - 4.6e-15 55.8 0.1 2e-06 28.0 0.0 2.1 1 1 1 2 2 2 2 Iron-sulphur cluster biosynthesis DUF3797 PF12677.7 CCD22942.1 - 0.095 12.6 0.6 11 6.0 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) SRP1_TIP1 PF00660.17 CCD22943.1 - 2.2e-32 111.1 0.4 1.6e-31 108.2 0.0 2.8 2 0 0 2 2 2 1 Seripauperin and TIP1 family AIM3 PF17096.5 CCD22944.1 - 2.9e-27 95.4 26.3 2.9e-27 95.4 26.3 8.7 7 4 1 8 8 8 1 Altered inheritance of mitochondria protein 3 Glycos_transf_1 PF00534.20 CCD22945.1 - 2e-11 43.7 0.0 7.6e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCD22945.1 - 1.3e-08 35.4 0.0 1.6e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCD22945.1 - 8.2e-07 29.2 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 CCD22945.1 - 6.4e-05 23.3 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CCD22945.1 - 0.0081 16.6 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Spermine_synth PF01564.17 CCD22946.1 - 7.1e-75 250.6 0.1 9.6e-75 250.1 0.1 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CCD22946.1 - 1.7e-26 91.9 0.1 3e-26 91.1 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CCD22946.1 - 0.00017 22.2 0.0 0.00037 21.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCD22946.1 - 0.0015 19.2 0.1 0.0058 17.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 CCD22946.1 - 0.0037 16.5 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_18 PF12847.7 CCD22946.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CCD22946.1 - 0.1 12.1 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Oxidored_FMN PF00724.20 CCD22947.1 - 1.3e-23 83.8 0.0 1.5e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NUDIX PF00293.28 CCD22948.1 - 4.3e-17 62.4 0.0 1.4e-16 60.7 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain EnY2 PF10163.9 CCD22949.1 - 1.2e-23 83.3 2.3 1.4e-23 83.1 2.3 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 Nod1 PF17114.5 CCD22949.1 - 0.014 15.6 0.2 0.02 15.1 0.2 1.4 1 1 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 CHASE3 PF05227.13 CCD22949.1 - 0.022 14.7 0.5 0.025 14.5 0.5 1.1 1 0 0 1 1 1 0 CHASE3 domain Pox_E8 PF03394.13 CCD22949.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus E8 protein COMPASS-Shg1 PF05205.12 CCD22949.1 - 0.15 12.8 4.5 3.6 8.4 0.8 2.4 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 SNF2_N PF00176.23 CCD22950.1 - 6.5e-54 183.0 0.2 1.7e-53 181.6 0.1 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCD22950.1 - 9.3e-15 54.9 0.0 2.1e-13 50.6 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD22950.1 - 1e-09 38.6 0.2 1e-09 38.6 0.2 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 CCD22950.1 - 7.8e-08 32.1 11.3 7.8e-08 32.1 11.3 2.5 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 CCD22950.1 - 3.5e-07 30.2 0.0 7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase YL1 PF05764.13 CCD22950.1 - 0.00035 20.8 15.5 0.00063 19.9 15.5 1.4 1 0 0 1 1 1 1 YL1 nuclear protein zf-C3HC4_2 PF13923.6 CCD22950.1 - 0.00058 19.7 8.8 0.00058 19.7 8.8 2.6 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCD22950.1 - 0.00098 19.2 9.4 0.00098 19.2 9.4 2.3 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CCD22950.1 - 0.0016 18.4 5.5 0.0016 18.4 5.5 2.0 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CCD22950.1 - 0.003 17.9 9.5 0.003 17.9 9.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-Nse PF11789.8 CCD22950.1 - 0.0062 16.3 6.1 0.018 14.8 6.1 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.6 CCD22950.1 - 0.013 15.3 7.9 0.013 15.3 7.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MH2 PF03166.14 CCD22950.1 - 0.028 14.7 0.0 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 MH2 domain Zn_Tnp_IS91 PF14319.6 CCD22950.1 - 0.16 12.0 11.8 0.034 14.2 2.0 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain BUD22 PF09073.10 CCD22950.1 - 1.6 8.0 18.5 2.5 7.3 18.5 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 CCD22950.1 - 2.1 6.4 17.8 3.2 5.9 17.8 1.1 1 0 0 1 1 1 0 Nop14-like family zf-RING_10 PF16685.5 CCD22950.1 - 3.1 8.0 10.9 0.074 13.2 2.4 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 CCD22950.1 - 3.9 7.4 19.7 0.081 12.8 8.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Pilt PF15453.6 CCD22950.1 - 4.8 6.5 7.0 8 5.8 7.0 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions SR1P PF13790.6 CCD22950.1 - 5.4 7.2 7.0 3.2 7.9 0.3 2.8 2 0 0 2 2 2 0 SR1 protein NAD_binding_4 PF07993.12 CCD22951.1 - 8e-71 238.2 0.0 1.2e-70 237.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 CCD22951.1 - 2.8e-66 223.9 0.0 3.7e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CCD22951.1 - 1.4e-14 54.1 0.0 3.3e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 CCD22951.1 - 8e-10 38.6 0.0 1.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.20 CCD22951.1 - 4.5e-08 32.2 2.8 0.00011 21.1 0.7 2.2 2 0 0 2 2 2 2 Condensation domain 3Beta_HSD PF01073.19 CCD22951.1 - 4.1e-07 29.3 0.0 1.2e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 CCD22951.1 - 0.00021 22.2 0.1 0.0012 19.7 0.0 2.5 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 CCD22951.1 - 0.004 17.1 0.0 0.012 15.5 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CCD22951.1 - 0.049 13.0 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CCD22951.1 - 0.052 12.7 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Transketolase_N PF00456.21 CCD22952.1 - 2.2e-156 520.0 0.0 3.8e-156 519.2 0.0 1.4 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CCD22952.1 - 9.5e-46 155.7 0.0 1.5e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CCD22952.1 - 7.9e-08 32.2 0.0 1.9e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 CCD22952.1 - 4.5e-05 22.8 0.1 0.00017 20.9 0.1 1.9 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase XFP_C PF09363.10 CCD22952.1 - 0.0035 16.8 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 XFP C-terminal domain E1_dh PF00676.20 CCD22952.1 - 0.0075 15.3 0.0 0.034 13.1 0.0 1.8 2 0 0 2 2 2 1 Dehydrogenase E1 component Terpene_synth PF01397.21 CCD22952.1 - 0.24 11.1 0.0 0.59 9.8 0.0 1.6 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain zf-CCHC PF00098.23 CCD22953.1 - 3.2e-06 27.0 2.2 5.3e-06 26.3 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 CCD22953.1 - 0.017 15.4 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein eIF3g PF12353.8 CCD22953.1 - 0.032 14.6 0.4 0.054 13.9 0.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-C2H2_10 PF16588.5 CCD22953.1 - 0.26 11.1 3.2 0.47 10.2 3.2 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_5 PF14787.6 CCD22953.1 - 0.27 11.0 2.1 0.58 9.9 2.1 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger CIMR PF00878.18 CCD22955.1 - 1.4e-08 34.9 2.2 3.5e-05 23.9 0.2 3.2 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 CCD22955.1 - 2.7e-05 24.2 0.6 4.4e-05 23.5 0.6 1.4 1 0 0 1 1 1 1 Autophagy-related protein 27 PRKCSH_1 PF13015.6 CCD22955.1 - 5.9e-05 22.8 0.0 0.00011 21.9 0.0 1.5 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Man-6-P_recep PF02157.15 CCD22955.1 - 9.3e-05 21.6 0.0 0.00013 21.2 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor GTP_EFTU PF00009.27 CCD22956.1 - 4.4e-54 183.0 0.0 6.4e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CCD22956.1 - 5.2e-40 136.2 0.0 1.2e-39 135.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CCD22956.1 - 3.1e-14 53.1 1.8 3.1e-14 53.1 1.8 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCD22956.1 - 0.00044 20.3 0.1 0.011 15.8 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CCD22956.1 - 1.2 9.0 7.2 0.062 13.2 0.9 2.1 3 0 0 3 3 3 0 Elongation factor Tu domain 4 RRM_1 PF00076.22 CCD22957.1 - 2.5e-10 40.0 4.2 7.8e-07 28.8 0.0 3.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RP-C_C PF11800.8 CCD22957.1 - 0.086 12.9 3.8 0.15 12.2 3.8 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF724 PF05266.14 CCD22958.1 - 0.071 12.9 3.4 0.11 12.3 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) AI-2E_transport PF01594.16 CCD22958.1 - 7.8 5.5 5.3 2.3 7.3 1.9 1.7 1 1 1 2 2 2 0 AI-2E family transporter HGTP_anticodon PF03129.20 CCD22959.1 - 3.3e-22 78.5 0.2 3.3e-22 78.5 0.2 2.5 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CCD22959.1 - 2.9e-07 30.6 0.0 1e-06 28.8 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Ribosomal_L31 PF01197.18 CCD22960.1 - 0.073 13.3 0.0 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L31 Tau95 PF09734.9 CCD22961.1 - 7.9e-36 123.9 0.3 1.9e-35 122.7 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 CCD22961.1 - 1.7e-25 89.6 0.0 3.9e-25 88.5 0.0 1.7 1 0 0 1 1 1 1 Tau95 Triple barrel domain FliE PF02049.18 CCD22961.1 - 0.15 12.2 0.3 0.56 10.4 0.3 2.0 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE PP2C PF00481.21 CCD22962.1 - 2e-59 201.4 0.0 1e-56 192.4 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Glyco_transf_20 PF00982.21 CCD22963.1 - 4.5e-201 668.6 0.1 5.2e-201 668.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 CCD22963.1 - 0.0012 18.6 0.3 0.0031 17.2 0.1 1.7 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 CCD22963.1 - 0.072 12.6 1.1 1 8.9 0.2 2.7 2 1 0 2 2 2 0 Glycosyl transferases group 1 ATP-synt_ab PF00006.25 CCD22964.1 - 4.1e-66 222.7 0.0 6.1e-66 222.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CCD22964.1 - 5.6e-15 55.6 0.9 1.2e-14 54.6 0.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 CCD22964.1 - 0.051 12.5 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Atg14 PF10186.9 CCD22965.1 - 3.7e-16 59.1 15.9 5.8e-16 58.5 15.9 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_HK97_TLTM PF06120.11 CCD22965.1 - 0.53 9.4 9.8 0.39 9.9 8.0 1.7 1 1 0 1 1 1 0 Tail length tape measure protein PH_11 PF15413.6 CCD22965.1 - 0.58 10.6 0.0 0.58 10.6 0.0 2.7 3 1 0 3 3 3 0 Pleckstrin homology domain Oxidored_FMN PF00724.20 CCD22967.1 - 4.7e-134 447.0 0.0 5.4e-134 446.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SHE3 PF17078.5 CCD22968.1 - 2.3e-32 112.6 32.5 2.3e-32 112.6 32.5 2.2 1 1 1 2 2 2 1 SWI5-dependent HO expression protein 3 DUF1664 PF07889.12 CCD22968.1 - 0.018 15.1 3.4 0.018 15.1 3.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 CCD22968.1 - 0.029 13.7 19.6 0.52 9.6 12.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Macoilin PF09726.9 CCD22968.1 - 4.4 5.7 47.5 0.013 14.1 15.8 2.4 1 1 0 2 2 2 0 Macoilin family OmpH PF03938.14 CCD22968.1 - 5.2 7.4 17.2 0.38 11.1 5.5 2.8 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) PH PF00169.29 CCD22969.1 - 1.9e-08 34.8 8.9 4.5e-07 30.3 0.6 2.9 2 1 1 3 3 3 2 PH domain rRNA_processing PF08524.11 CCD22969.1 - 0.04 14.0 0.3 0.094 12.7 0.3 1.6 1 0 0 1 1 1 0 rRNA processing DUF4720 PF15846.5 CCD22969.1 - 0.072 12.9 0.1 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4720) PH_11 PF15413.6 CCD22969.1 - 0.87 10.0 14.4 0.5 10.8 1.8 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain IMUP PF15761.5 CCD22969.1 - 7.6 7.3 7.9 0.66 10.7 3.0 1.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein TFIIB PF00382.19 CCD22970.1 - 3.5e-43 145.5 2.6 9.1e-28 96.1 1.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CCD22970.1 - 5.1e-13 48.3 0.7 9.3e-13 47.5 0.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Ribosomal_60s PF00428.19 CCD22970.1 - 0.00029 21.3 7.5 0.00045 20.7 2.5 2.9 3 0 0 3 3 3 1 60s Acidic ribosomal protein zf-ribbon_3 PF13248.6 CCD22970.1 - 0.15 11.5 0.5 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain RecO_N PF11967.8 CCD22970.1 - 0.17 11.8 0.1 0.37 10.8 0.1 1.5 1 0 0 1 1 1 0 Recombination protein O N terminal SRP54 PF00448.22 CCD22971.1 - 4.1e-78 261.5 0.6 4.1e-78 261.5 0.6 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CCD22971.1 - 5e-29 100.8 12.9 5e-29 100.8 12.9 4.1 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 CCD22971.1 - 3.2e-14 52.9 1.4 3.2e-14 52.9 1.4 2.2 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain SRPRB PF09439.10 CCD22971.1 - 6.6e-05 22.4 3.3 1.6 8.1 0.1 3.8 3 0 0 3 3 3 2 Signal recognition particle receptor beta subunit cobW PF02492.19 CCD22971.1 - 7.2e-05 22.4 2.8 0.00035 20.2 1.2 2.7 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CCD22971.1 - 9.5e-05 22.6 0.0 0.00025 21.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CCD22971.1 - 0.00019 21.5 0.0 0.0007 19.6 0.0 2.2 2 1 0 2 2 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 CCD22971.1 - 0.00027 21.4 0.1 0.0012 19.3 0.1 2.1 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 CCD22971.1 - 0.0015 18.4 0.0 0.0051 16.7 0.0 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 CCD22971.1 - 0.002 17.4 0.1 0.0064 15.8 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin MeaB PF03308.16 CCD22971.1 - 0.0046 16.0 1.2 0.019 14.0 0.0 2.6 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 CCD22971.1 - 0.011 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 CCD22971.1 - 0.013 15.3 0.1 0.047 13.5 0.1 2.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 CCD22971.1 - 0.015 15.8 0.1 0.052 14.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 CCD22971.1 - 0.023 14.4 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 CCD22971.1 - 0.03 14.3 2.5 0.04 13.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CCD22971.1 - 0.047 14.0 0.6 0.17 12.1 0.3 2.2 2 1 0 2 2 1 0 AAA domain VirE PF05272.11 CCD22971.1 - 0.05 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Virulence-associated protein E VirC1 PF07015.11 CCD22971.1 - 0.053 12.8 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein MipZ PF09140.11 CCD22971.1 - 0.054 12.8 0.1 1.2 8.3 0.1 2.5 1 1 0 1 1 1 0 ATPase MipZ AAA_16 PF13191.6 CCD22971.1 - 0.055 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CCD22971.1 - 0.078 13.4 1.1 0.99 9.8 0.9 2.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CCD22971.1 - 0.082 12.6 2.1 0.12 12.1 0.1 2.2 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 CCD22971.1 - 0.098 12.7 2.1 0.4 10.8 0.4 2.8 3 1 0 3 3 3 0 50S ribosome-binding GTPase AAA_28 PF13521.6 CCD22971.1 - 0.21 11.8 0.1 0.64 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CCD22971.1 - 1.6 8.6 5.3 2.2 8.2 2.7 2.5 2 1 0 2 2 1 0 NTPase ResIII PF04851.15 CCD22971.1 - 1.8 8.5 5.2 0.98 9.4 1.5 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF1712 PF08217.11 CCD22972.1 - 9.3e-159 529.7 25.8 1.1e-158 529.6 25.8 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) DUF5595 PF18077.1 CCD22972.1 - 0.014 15.5 0.2 0.05 13.7 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) DUF126 PF01989.16 CCD22972.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Aconitase X swivel domain AA_permease PF00324.21 CCD22973.1 - 4.8e-126 421.2 33.4 5.5e-126 421.0 33.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD22973.1 - 3.1e-21 75.7 36.3 4.1e-21 75.3 36.3 1.1 1 0 0 1 1 1 1 Amino acid permease ATP-synt_DE_N PF02823.16 CCD22974.1 - 1.5e-15 56.9 0.0 2e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Rad21_Rec8_N PF04825.13 CCD22975.1 - 4.2e-23 81.6 0.2 1.7e-22 79.7 0.2 2.0 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CCD22975.1 - 4.7e-11 41.8 0.0 1e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein CNDH2_N PF06278.11 CCD22975.1 - 0.039 14.2 0.1 0.039 14.2 0.1 3.2 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Ycf34 PF10718.9 CCD22975.1 - 0.15 12.7 0.2 0.94 10.2 0.2 2.4 1 0 0 1 1 1 0 Hypothetical chloroplast protein Ycf34 DRIM PF07539.12 CCD22976.1 - 2.4e-166 554.7 12.9 2.4e-166 554.7 12.9 4.2 4 1 0 4 4 4 1 Down-regulated in metastasis DUF4042 PF13251.6 CCD22976.1 - 0.012 15.3 7.8 1.6 8.4 0.0 5.3 8 0 0 8 8 8 0 Domain of unknown function (DUF4042) ParcG PF10274.9 CCD22976.1 - 0.039 14.1 5.0 5.1 7.2 0.1 5.4 5 0 0 5 5 5 0 Parkin co-regulated protein RTP1_C1 PF10363.9 CCD22976.1 - 0.29 11.3 4.9 29 4.9 0.0 5.6 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 NYD-SP28_assoc PF14775.6 CCD22976.1 - 4.3 7.5 7.6 5.8 7.1 0.6 3.6 3 0 0 3 3 3 0 Sperm tail C-terminal domain DOR PF14839.6 CCD22976.1 - 6.5 6.6 6.9 14 5.5 6.9 1.6 1 0 0 1 1 1 0 DOR family KxDL PF10241.9 CCD22977.1 - 0.017 15.4 2.2 0.038 14.3 0.9 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein Prefoldin_2 PF01920.20 CCD22978.1 - 8.6e-22 77.1 5.6 1.1e-21 76.8 5.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit GIT_CC PF16559.5 CCD22978.1 - 0.0036 17.1 2.2 1 9.3 0.1 2.2 2 0 0 2 2 2 2 GIT coiled-coil Rho guanine nucleotide exchange factor SAS4 PF15460.6 CCD22978.1 - 0.25 11.5 4.5 0.23 11.6 0.8 2.0 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 Occludin_ELL PF07303.13 CCD22978.1 - 0.46 11.2 5.0 6.3 7.6 0.8 2.1 1 1 1 2 2 2 0 Occludin homology domain DUF2205 PF10224.9 CCD22978.1 - 0.5 10.4 4.0 0.74 9.9 0.3 2.1 2 0 0 2 2 2 0 Short coiled-coil protein DDOST_48kD PF03345.14 CCD22979.1 - 1e-121 406.7 7.2 1.2e-121 406.4 7.2 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF2555 PF10742.9 CCD22979.1 - 0.081 12.8 1.0 3.9 7.4 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) T6PP_N PF18572.1 CCD22980.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain GDA1_CD39 PF01150.17 CCD22981.1 - 4.9e-146 486.7 1.3 9.2e-146 485.8 1.3 1.4 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family SRP9-21 PF05486.12 CCD22981.1 - 0.27 11.6 1.2 0.66 10.4 1.2 1.7 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) GN3L_Grn1 PF08701.11 CCD22982.1 - 3e-23 81.7 16.4 8e-23 80.3 16.4 1.8 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 CCD22982.1 - 4.1e-18 65.5 0.1 1.1e-13 51.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CCD22982.1 - 4.6e-09 36.0 0.2 9.2e-08 31.8 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CCD22982.1 - 2e-06 28.0 3.7 0.066 13.3 0.9 3.6 2 2 0 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 CCD22982.1 - 9.2e-06 25.7 0.3 0.00046 20.1 0.3 2.4 1 1 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 CCD22982.1 - 0.00044 19.6 0.1 0.0019 17.6 0.0 2.1 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 CCD22982.1 - 0.00051 19.6 0.0 0.15 11.5 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 CCD22982.1 - 0.031 13.2 0.0 0.065 12.2 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 CCD22982.1 - 0.043 14.0 0.9 3.1 8.0 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 CCD22982.1 - 0.092 13.3 0.6 0.58 10.7 0.0 2.6 3 1 0 3 3 3 0 AAA domain Torsin PF06309.11 CCD22982.1 - 0.17 12.0 0.1 0.38 10.9 0.1 1.5 1 0 0 1 1 1 0 Torsin AAA_16 PF13191.6 CCD22982.1 - 1.3 9.4 4.3 3.9 7.8 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain Pre-PUA PF17832.1 CCD22983.1 - 6e-27 94.2 0.7 1.5e-26 92.9 0.9 1.5 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 CCD22983.1 - 3.2e-21 75.1 0.0 4.7e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 CCD22983.1 - 7.8e-05 22.9 1.0 0.00023 21.4 0.3 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF1947) Sec3_C PF09763.9 CCD22984.1 - 2.1e-150 502.4 28.6 2.1e-150 502.4 28.6 2.4 3 0 0 3 3 3 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 CCD22984.1 - 2.8e-28 97.8 0.7 2.8e-28 97.8 0.7 2.3 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 CCD22984.1 - 2.1e-08 33.4 2.0 4.1e-08 32.4 2.0 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family NTF2 PF02136.20 CCD22985.1 - 2.2e-36 125.1 0.5 2.5e-36 124.9 0.5 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.6 CCD22985.1 - 0.002 17.3 0.5 0.014 14.6 0.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) RraA-like PF03737.15 CCD22986.1 - 1.6e-26 93.3 0.0 2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA EF-hand_4 PF12763.7 CCD22987.1 - 2.5e-29 101.3 0.0 3.3e-14 52.7 0.0 3.3 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CCD22987.1 - 7.6e-07 29.5 0.0 0.0026 18.1 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CCD22987.1 - 1.2e-06 27.6 0.0 0.0018 17.7 0.0 3.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 CCD22987.1 - 5.4e-06 25.9 0.0 0.025 14.5 0.0 4.2 4 0 0 4 4 4 1 EF-hand domain DUF1720 PF08226.11 CCD22987.1 - 0.00099 19.5 50.2 0.0038 17.6 11.1 10.3 3 3 5 8 8 8 4 Domain of unknown function (DUF1720) Cwf_Cwc_15 PF04889.12 CCD22987.1 - 0.0023 17.7 20.3 0.0023 17.7 20.3 4.3 3 1 1 4 4 4 1 Cwf15/Cwc15 cell cycle control protein SRP1_TIP1 PF00660.17 CCD22988.1 - 6.5e-35 119.2 3.3 6.5e-35 119.2 0.0 2.2 2 1 0 2 2 2 1 Seripauperin and TIP1 family PIR PF00399.19 CCD22988.1 - 9.2e-06 25.1 9.1 0.0001 21.7 9.1 3.1 1 0 0 1 1 1 1 Yeast PIR protein repeat SOG2 PF10428.9 CCD22988.1 - 0.19 10.9 19.8 0.25 10.5 19.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SAPS PF04499.15 CCD22988.1 - 0.19 10.5 3.3 0.19 10.5 3.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hamartin PF04388.12 CCD22988.1 - 0.53 8.9 10.6 0.56 8.8 10.6 1.1 1 0 0 1 1 1 0 Hamartin protein DDHD PF02862.17 CCD22988.1 - 1.8 8.7 8.9 2.9 8.0 8.9 1.4 1 0 0 1 1 1 0 DDHD domain Macoilin PF09726.9 CCD22988.1 - 3.2 6.2 18.2 4.2 5.8 18.2 1.1 1 0 0 1 1 1 0 Macoilin family SRP-alpha_N PF04086.13 CCD22988.1 - 3.6 7.4 13.3 4.7 7.1 13.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TFIIA PF03153.13 CCD22988.1 - 4 7.3 13.2 5.1 7.0 13.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CCD22988.1 - 4.4 6.0 12.0 6 5.5 12.0 1.2 1 0 0 1 1 1 0 Presenilin Utp14 PF04615.13 CCD22988.1 - 5.1 5.5 17.6 6.6 5.2 17.6 1.1 1 0 0 1 1 1 0 Utp14 protein DUF572 PF04502.13 CCD22988.1 - 9.8 5.7 12.6 13 5.3 12.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) ABC2_membrane PF01061.24 CCD22990.1 - 1.4e-66 223.9 64.8 4.9e-35 120.8 15.9 3.2 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 CCD22990.1 - 2.5e-28 99.3 0.0 1.1e-15 58.3 0.0 2.9 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CCD22990.1 - 7.3e-28 96.3 4.6 2.5e-25 88.2 0.1 4.3 4 0 0 4 4 4 2 CDR ABC transporter RsgA_GTPase PF03193.16 CCD22990.1 - 8.3e-06 25.8 0.2 1.7e-05 24.8 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 CCD22990.1 - 2.5e-05 24.3 1.9 0.0035 17.2 0.3 2.8 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 CCD22990.1 - 2.6e-05 23.5 59.2 0.0028 16.8 17.6 3.8 2 2 1 3 3 3 2 ABC-2 family transporter protein SMC_N PF02463.19 CCD22990.1 - 0.00034 20.1 0.5 0.018 14.5 0.5 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CCD22990.1 - 0.0022 18.4 0.1 0.0049 17.3 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 CCD22990.1 - 0.004 17.7 0.1 0.014 15.9 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCD22990.1 - 0.042 14.1 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CCD22990.1 - 0.05 13.3 0.2 0.13 12.0 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CCD22990.1 - 0.076 12.6 0.3 0.23 11.0 0.0 1.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CCD22990.1 - 0.091 13.3 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CCD22990.1 - 0.16 12.1 0.4 0.65 10.1 0.1 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Wzz PF02706.15 CCD22990.1 - 0.17 12.2 1.0 1.2 9.5 0.1 3.0 2 0 0 2 2 2 0 Chain length determinant protein TOM13 PF08219.11 CCD22991.1 - 2e-25 88.6 0.1 3.1e-25 88.0 0.1 1.4 1 0 0 1 1 1 1 Outer membrane protein TOM13 LETM1 PF07766.13 CCD22992.1 - 1e-98 329.9 6.1 2.1e-98 328.9 6.1 1.5 1 0 0 1 1 1 1 LETM1-like protein bZIP_1 PF00170.21 CCD22993.1 - 0.0034 17.4 9.2 0.0034 17.4 9.2 2.6 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CCD22993.1 - 0.012 15.7 10.0 0.012 15.7 10.0 2.2 3 0 0 3 3 3 0 Basic region leucine zipper bZIP_Maf PF03131.17 CCD22993.1 - 2.6 8.6 12.8 0.15 12.6 6.4 2.1 2 1 1 3 3 3 0 bZIP Maf transcription factor Glyco_hydro_72 PF03198.14 CCD22994.1 - 2.6e-147 490.2 10.5 3.3e-147 489.8 10.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 CCD22994.1 - 2.9e-05 23.6 0.3 0.00024 20.6 0.3 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Lys PF00062.20 CCD22994.1 - 0.048 13.9 0.8 5.8 7.2 0.1 2.5 2 0 0 2 2 2 0 C-type lysozyme/alpha-lactalbumin family DUF2653 PF10850.8 CCD22994.1 - 0.057 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2653) Nop14 PF04147.12 CCD22994.1 - 0.22 9.7 6.2 0.31 9.2 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 CCD22994.1 - 0.45 9.9 5.3 0.58 9.5 5.3 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 CCD22994.1 - 0.57 9.4 4.5 0.96 8.7 4.5 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 CCD22994.1 - 1.3 7.0 13.1 1.9 6.5 13.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Apt1 PF10351.9 CCD22994.1 - 1.5 7.6 16.1 2.4 6.9 16.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 CCD22994.1 - 5.5 6.5 31.5 12 5.5 31.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PBP1_TM PF14812.6 CCD22994.1 - 6.9 7.1 7.5 13 6.2 7.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pes-10 PF07149.11 CCD22994.1 - 8.8 5.3 8.4 18 4.2 5.9 2.3 3 0 0 3 3 3 0 Pes-10 Pet127 PF08634.10 CCD22995.1 - 8.2e-104 346.9 9.8 8.2e-104 346.9 9.8 2.4 2 1 0 2 2 2 1 Mitochondrial protein Pet127 MRP-L47 PF06984.13 CCD22995.1 - 0.15 12.2 1.8 0.57 10.3 0.4 2.7 3 0 0 3 3 3 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) RBD PF02196.15 CCD22995.1 - 0.19 11.8 0.9 0.54 10.4 0.2 2.2 2 0 0 2 2 2 0 Raf-like Ras-binding domain RB_A PF01858.17 CCD22995.1 - 1.9 8.3 9.7 0.063 13.1 1.0 2.7 3 0 0 3 3 3 0 Retinoblastoma-associated protein A domain EMP24_GP25L PF01105.24 CCD22996.1 - 1.8e-35 122.5 0.0 2.1e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CRAL_TRIO_N PF03765.15 CCD22996.1 - 0.019 15.1 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain B56 PF01603.20 CCD22997.1 - 7.6e-169 562.1 22.7 3e-160 533.7 14.5 2.2 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) AAA_23 PF13476.6 CCD22998.1 - 6.5e-19 69.2 13.3 6.5e-19 69.2 13.3 5.0 2 2 1 4 4 4 1 AAA domain SMC_N PF02463.19 CCD22998.1 - 1.4e-13 50.8 35.1 5e-13 49.0 35.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCD22998.1 - 0.00011 21.9 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CCD22998.1 - 0.0026 17.6 49.1 0.0026 17.6 49.1 4.2 2 2 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 CCD22998.1 - 0.023 14.5 0.2 0.023 14.5 0.2 4.2 3 2 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 CCD22998.1 - 0.027 15.0 0.0 0.027 15.0 0.0 5.2 3 2 0 4 4 4 0 ABC transporter AAA_25 PF13481.6 CCD22998.1 - 0.095 12.3 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cob_adeno_trans PF01923.18 CCD22998.1 - 0.16 12.1 24.1 0.18 12.0 5.5 4.9 4 1 0 4 4 4 0 Cobalamin adenosyltransferase AAA_27 PF13514.6 CCD22998.1 - 0.18 11.4 0.0 0.18 11.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain FUSC PF04632.12 CCD22998.1 - 9.7 4.6 5.7 2 6.9 1.9 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family tRNA-synt_1c PF00749.21 CCD22999.1 - 4.5e-108 360.9 0.0 7.1e-108 360.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain UxuA PF03786.13 CCD22999.1 - 0.036 12.9 0.4 0.06 12.2 0.0 1.5 2 0 0 2 2 2 0 D-mannonate dehydratase (UxuA) Put_DNA-bind_N PF06971.13 CCD22999.1 - 0.087 12.9 0.3 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus ADH_N PF08240.12 CCD23000.1 - 2.2e-26 91.9 2.7 3.8e-26 91.1 2.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCD23000.1 - 2.2e-19 69.7 0.1 4.2e-19 68.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CCD23000.1 - 2.6e-05 23.7 0.5 5.5e-05 22.6 0.5 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CCD23000.1 - 0.0014 18.0 0.1 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Rep_1B PF17873.1 CCD23000.1 - 9.5 6.2 10.0 8.6 6.3 0.1 3.6 3 0 0 3 3 3 0 Replicase polyprotein 1ab DUF775 PF05603.12 CCD23001.1 - 4.1e-61 206.0 0.2 5.4e-61 205.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) SIL1 PF16782.5 CCD23002.1 - 2.9e-108 361.5 16.2 5.1e-108 360.7 16.2 1.4 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 Ribosomal_60s PF00428.19 CCD23003.1 - 1.5e-25 89.6 8.8 1.8e-25 89.4 8.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein RRM_1 PF00076.22 CCD23004.1 - 2.9e-18 65.4 3.1 5e-14 51.9 0.1 4.4 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD23004.1 - 1.1e-05 25.4 1.8 0.095 12.8 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif Spo7_2_N PF15407.6 CCD23004.1 - 0.00034 20.2 0.1 0.0025 17.4 0.0 2.5 2 0 0 2 2 2 1 Sporulation protein family 7 Nup35_RRM PF05172.13 CCD23004.1 - 0.032 14.2 0.1 0.1 12.6 0.1 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CCD23004.1 - 0.085 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Mitofilin PF09731.9 CCD23005.1 - 0.21 10.4 5.9 0.31 9.8 5.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Exo_endo_phos PF03372.23 CCD23006.1 - 1.9e-10 40.7 0.0 3.6e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CCD23006.1 - 0.11 12.4 0.2 0.83 9.5 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase HNF-1_N PF04814.13 CCD23007.1 - 0.00093 19.9 0.6 0.00093 19.9 0.6 1.8 2 0 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus PolyA_pol_RNAbd PF12627.7 CCD23007.1 - 0.53 10.1 2.9 2 8.2 0.2 2.8 3 0 0 3 3 3 0 Probable RNA and SrmB- binding site of polymerase A Mannosyl_trans3 PF11051.8 CCD23008.1 - 1.1e-72 244.7 2.2 1.5e-72 244.3 2.2 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Pkinase PF00069.25 CCD23009.1 - 8.1e-60 202.4 1.2 2.7e-59 200.7 0.1 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23009.1 - 1.7e-19 70.1 0.0 3.2e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD23009.1 - 3.4e-08 33.1 0.0 8.1e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CCD23009.1 - 0.0014 18.0 0.1 0.0032 16.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.7 CCD23009.1 - 0.01 16.1 1.1 0.31 11.3 0.1 3.6 3 0 0 3 3 3 0 PAS domain PAS PF00989.25 CCD23009.1 - 0.016 15.2 0.0 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 PAS fold Pkinase_fungal PF17667.1 CCD23009.1 - 0.034 12.9 0.7 0.059 12.1 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 CCD23009.1 - 0.038 13.6 0.1 0.13 11.8 0.1 1.9 1 0 0 1 1 1 0 RIO1 family NOC3p PF07540.11 CCD23009.1 - 0.1 13.1 0.2 0.44 11.0 0.2 2.1 1 0 0 1 1 1 0 Nucleolar complex-associated protein EI24 PF07264.11 CCD23010.1 - 1e-08 35.6 4.8 1.4e-08 35.2 4.8 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) LAMTOR PF15454.6 CCD23010.1 - 0.11 13.1 1.8 0.23 12.1 1.8 1.5 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator GSH_synth_ATP PF03917.17 CCD23011.1 - 4.7e-118 394.2 0.0 5.4e-118 394.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CCD23011.1 - 7.3e-31 106.7 0.1 1.9e-30 105.4 0.1 1.7 1 0 0 1 1 1 1 Eukaryotic glutathione synthase PMT PF02366.18 CCD23013.1 - 3.5e-86 288.8 18.0 3.5e-86 288.8 18.0 2.1 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCD23013.1 - 1.9e-56 190.9 20.0 1.9e-56 190.9 20.0 2.4 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCD23013.1 - 1.2e-25 90.5 0.7 1.2e-25 90.5 0.7 1.8 2 0 0 2 2 2 1 MIR domain LDB19 PF13002.7 CCD23014.1 - 5.8e-92 306.7 1.1 1e-91 305.9 1.1 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 CCD23014.1 - 0.00023 21.3 0.4 0.00069 19.7 0.1 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain UBM PF14377.6 CCD23014.1 - 3.4 7.3 5.7 6.7 6.3 5.7 1.5 1 0 0 1 1 1 0 Ubiquitin binding region Ribosomal_L28e PF01778.17 CCD23015.1 - 5.8e-41 139.9 0.7 5.8e-41 139.9 0.7 2.2 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.14 CCD23015.1 - 6.2e-30 103.8 17.4 6.2e-30 103.8 17.4 2.6 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 CCD23015.1 - 7.5e-06 25.6 26.5 9.5e-06 25.2 26.5 1.1 1 0 0 1 1 1 1 BUD22 TFIIF_alpha PF05793.12 CCD23015.1 - 0.13 10.8 33.6 0.16 10.6 33.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2462 PF09495.10 CCD23015.1 - 0.15 12.8 6.5 0.87 10.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2462) PYC_OADA PF02436.18 CCD23015.1 - 0.47 10.2 5.8 0.87 9.3 5.8 1.6 1 1 0 1 1 1 0 Conserved carboxylase domain DUF4611 PF15387.6 CCD23015.1 - 1 9.6 25.6 0.19 12.0 11.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Aldedh PF00171.22 CCD23016.1 - 1.1e-16 60.5 0.2 6.6e-14 51.3 0.1 2.5 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Phage_sheath_1C PF17482.2 CCD23016.1 - 0.012 15.5 0.2 0.059 13.4 0.1 2.2 2 0 0 2 2 2 0 Phage tail sheath C-terminal domain URO-D PF01208.17 CCD23016.1 - 0.095 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) FliJ PF02050.16 CCD23017.1 - 0.79 10.0 13.8 0.087 13.0 2.3 2.7 3 0 0 3 3 3 0 Flagellar FliJ protein Peptidase_C98 PF15499.6 CCD23017.1 - 0.8 9.1 7.8 0.045 13.2 0.6 2.3 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Myosin_head PF00063.21 CCD23018.1 - 2.2e-280 931.7 18.8 2.2e-280 931.7 18.8 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 CCD23018.1 - 4e-26 91.3 0.4 4e-26 91.3 0.4 2.5 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 CCD23018.1 - 3.8e-08 32.4 18.1 0.13 12.1 0.5 6.0 5 0 0 5 5 5 4 IQ calmodulin-binding motif AAA_22 PF13401.6 CCD23018.1 - 0.0032 17.7 0.8 0.014 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Myosin_N PF02736.19 CCD23018.1 - 0.026 14.4 0.1 0.076 12.9 0.1 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain ABC_tran PF00005.27 CCD23018.1 - 0.14 12.6 0.0 0.14 12.6 0.0 3.1 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 CCD23018.1 - 0.23 11.8 2.6 0.49 10.8 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain HSF_DNA-bind PF00447.17 CCD23018.1 - 1.7 9.3 4.9 0.67 10.6 0.3 2.8 2 0 0 2 2 2 0 HSF-type DNA-binding T6PP_N PF18572.1 CCD23018.1 - 9.9 6.1 21.1 50 3.8 0.0 4.8 3 1 0 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Synaptobrevin PF00957.21 CCD23019.1 - 2e-31 107.6 1.7 2.3e-31 107.4 1.7 1.0 1 0 0 1 1 1 1 Synaptobrevin UPF0258 PF06789.12 CCD23019.1 - 0.26 11.4 1.5 0.37 10.9 1.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Glu-tRNAGln PF02686.15 CCD23020.1 - 0.14 12.5 0.4 1.2 9.5 0.1 2.6 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit bZIP_2 PF07716.15 CCD23021.1 - 2.9e-11 43.3 10.9 2.9e-11 43.3 10.9 2.2 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 CCD23021.1 - 4.4e-09 36.3 10.8 4.4e-09 36.3 10.8 2.3 3 0 0 3 3 3 1 bZIP transcription factor bZIP_Maf PF03131.17 CCD23021.1 - 0.0024 18.4 7.4 0.0024 18.4 7.4 2.3 3 0 0 3 3 3 1 bZIP Maf transcription factor Urm1 PF09138.11 CCD23022.1 - 1.3e-36 124.9 0.5 1.4e-36 124.7 0.5 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 CCD23022.1 - 0.00036 21.1 0.1 0.00047 20.8 0.1 1.2 1 0 0 1 1 1 1 ThiS family DUF1281 PF06924.11 CCD23023.1 - 0.0016 18.0 0.7 0.021 14.4 0.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1281) COPIIcoated_ERV PF07970.12 CCD23024.1 - 1.5e-74 250.5 0.3 1.9e-74 250.3 0.3 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CCD23024.1 - 2.7e-28 98.1 0.1 6.1e-28 97.0 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PX PF00787.24 CCD23025.1 - 7.4e-22 77.5 0.2 1.6e-21 76.4 0.2 1.5 1 0 0 1 1 1 1 PX domain Histone PF00125.24 CCD23026.1 - 2.6e-23 82.8 0.0 4.6e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCD23026.1 - 8.3e-19 67.6 1.1 1.6e-18 66.8 1.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.14 CCD23026.1 - 0.00047 20.2 0.1 0.0013 18.8 0.1 1.8 2 0 0 2 2 2 1 hTAFII28-like protein conserved region SAM_2 PF07647.17 CCD23027.1 - 1.8e-06 28.0 0.0 4.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CCD23027.1 - 0.00072 19.9 0.1 0.0017 18.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDEase_I PF00233.19 CCD23028.1 - 1.2e-49 169.2 6.4 2.9e-49 167.9 6.4 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CCD23028.1 - 0.0092 16.2 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 HD domain ATP-grasp_6 PF18419.1 CCD23028.1 - 0.032 13.9 0.1 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp-like domain eIF2A PF08662.11 CCD23029.1 - 4.4e-24 85.4 3.0 1.5e-21 77.1 0.4 3.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 CCD23029.1 - 4.2e-09 36.1 0.1 9.6e-09 34.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spindle_Spc25 PF08234.12 CCD23029.1 - 0.057 13.6 0.1 0.18 12.0 0.1 1.8 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 WD40 PF00400.32 CCD23029.1 - 0.19 12.7 0.8 8.2 7.5 0.1 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Proteasome PF00227.26 CCD23030.1 - 3.1e-50 170.3 0.0 4.7e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCD23030.1 - 4.6e-11 42.2 1.0 6.9e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DLH PF01738.18 CCD23031.1 - 1.5e-35 122.7 0.0 1.8e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 CCD23031.1 - 0.12 11.6 0.0 4.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2766 PF10964.8 CCD23031.1 - 0.14 12.1 0.0 41 4.2 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2766) Zn_clus PF00172.18 CCD23032.1 - 9.4e-11 41.7 9.7 1.7e-10 40.9 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CH PF00307.31 CCD23033.1 - 1.5e-14 54.1 0.0 2e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Peroxin-22 PF12827.7 CCD23034.1 - 3.8e-27 94.5 4.9 4.7e-27 94.2 4.4 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis protein family SARAF PF06682.12 CCD23034.1 - 0.018 14.7 0.1 0.021 14.5 0.1 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF370 PF04025.12 CCD23034.1 - 0.02 15.0 1.0 0.02 15.0 1.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF370) Holin_SPP1 PF04688.13 CCD23034.1 - 0.029 14.6 0.8 0.056 13.6 0.8 1.5 1 0 0 1 1 1 0 SPP1 phage holin G0-G1_switch_2 PF15103.6 CCD23034.1 - 0.061 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 Rad1 PF02144.16 CCD23035.1 - 7.5e-67 225.3 0.5 1e-66 224.8 0.5 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ribosomal_L7Ae PF01248.26 CCD23036.1 - 1.8e-23 82.0 0.2 2.4e-23 81.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.12 CCD23036.1 - 0.048 14.0 0.6 0.2 12.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) GhoS PF11080.8 CCD23036.1 - 0.38 10.8 2.0 2.7 8.1 0.0 2.3 1 1 0 2 2 2 0 Endoribonuclease GhoS GDI PF00996.18 CCD23037.1 - 5.4e-45 153.7 0.7 1.1e-44 152.7 0.0 1.7 2 1 0 2 2 2 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CCD23037.1 - 0.0089 16.2 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 CCD23037.1 - 0.019 14.5 0.1 0.88 9.1 0.1 2.3 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 CCD23037.1 - 0.11 11.8 0.0 0.22 10.7 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Kelch_3 PF13415.6 CCD23038.1 - 5.9e-10 39.2 1.8 0.0027 18.0 0.0 5.0 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CCD23038.1 - 4e-09 36.4 9.5 8.5e-06 25.7 0.4 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CCD23038.1 - 3.5e-07 30.1 11.2 0.7 10.0 0.1 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 CCD23038.1 - 2.2e-06 27.8 6.1 0.033 14.5 0.4 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 CCD23038.1 - 0.0056 16.6 9.3 0.52 10.4 1.6 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 CCD23038.1 - 0.006 16.1 7.3 0.33 10.6 0.3 4.2 5 0 0 5 5 5 2 Kelch motif LRR_4 PF12799.7 CCD23040.1 - 3.7e-07 30.3 33.7 6.3e-05 23.3 0.6 9.2 6 2 2 9 9 9 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CCD23040.1 - 0.00019 21.2 24.4 1.1 9.5 1.1 7.1 6 0 0 6 6 6 5 Leucine Rich repeat LRR_9 PF14580.6 CCD23040.1 - 0.0004 19.9 27.8 0.074 12.6 0.4 5.1 2 1 2 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.6 CCD23040.1 - 0.011 15.5 3.4 0.011 15.5 3.4 7.2 6 3 2 8 8 8 0 Leucine rich repeat Aldedh PF00171.22 CCD23041.1 - 4.3e-178 592.5 0.3 5.1e-178 592.3 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_transf_15 PF01793.16 CCD23042.1 - 1.7e-128 428.5 17.0 2.1e-128 428.2 17.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SRP1_TIP1 PF00660.17 CCD23043.1 - 1.6e-32 111.5 0.6 1.6e-32 111.5 0.6 2.6 2 0 0 2 2 2 1 Seripauperin and TIP1 family Toxin_6 PF05453.12 CCD23043.1 - 4.3 7.9 14.1 17 5.9 0.3 3.5 4 0 0 4 4 4 0 BmTXKS1/BmP02 toxin family Pmp3 PF01679.17 CCD23044.1 - 1.5e-15 57.1 7.9 2e-15 56.7 7.9 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Colicin PF01024.19 CCD23045.1 - 0.51 10.2 4.0 0.38 10.6 0.3 2.1 2 0 0 2 2 2 0 Colicin pore forming domain NAD_binding_5 PF07994.12 CCD23046.1 - 3.4e-139 463.7 0.2 4.3e-139 463.4 0.2 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CCD23046.1 - 6.3e-43 145.5 3.1 1.6e-42 144.2 2.5 2.0 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Vps35 PF03635.17 CCD23047.1 - 8.2e-192 639.5 45.0 9.9e-192 639.3 45.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF3446 PF11928.8 CCD23047.1 - 0.00094 19.4 20.2 0.038 14.3 0.3 4.6 4 0 0 4 4 4 2 Early growth response N-terminal domain PH_13 PF16652.5 CCD23047.1 - 2.3 8.0 11.4 0.064 13.1 1.8 3.1 3 0 0 3 3 3 0 Pleckstrin homology domain 6PF2K PF01591.18 CCD23048.1 - 1.2e-80 270.1 2.8 1.8e-80 269.4 2.8 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CCD23048.1 - 1.5e-37 129.2 0.0 2e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CCD23048.1 - 2.9e-05 24.3 0.0 7e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCD23048.1 - 0.0012 19.4 0.0 0.0025 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CCD23048.1 - 0.0066 15.9 0.2 0.011 15.2 0.2 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 CCD23048.1 - 0.043 13.1 0.0 0.13 11.5 0.0 1.8 1 1 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 CCD23048.1 - 0.052 14.0 0.0 0.31 11.5 0.0 2.2 3 0 0 3 3 3 0 AAA domain Peptidase_S64 PF08192.11 CCD23049.1 - 1.3e-276 919.6 16.6 1.7e-276 919.3 16.6 1.1 1 0 0 1 1 1 1 Peptidase family S64 Thioredoxin_8 PF13905.6 CCD23050.1 - 0.035 14.4 0.1 0.59 10.5 0.2 2.7 2 0 0 2 2 2 0 Thioredoxin-like zf-RING_2 PF13639.6 CCD23050.1 - 0.086 13.2 6.1 0.43 10.9 6.4 2.1 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 CCD23050.1 - 0.24 11.3 6.0 0.73 9.7 6.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CCD23050.1 - 0.37 10.6 6.6 1.2 8.9 2.5 2.7 2 0 0 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 CCD23050.1 - 0.39 10.4 2.9 0.92 9.2 2.9 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 CCD23050.1 - 0.4 10.7 6.4 8.4 6.4 0.5 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 CCD23050.1 - 5.2 7.1 6.4 14 5.7 6.5 1.8 1 1 0 1 1 1 0 zinc-RING finger domain PIR PF00399.19 CCD23051.1 - 6.4e-05 22.4 5.4 6.4e-05 22.4 5.4 2.7 2 0 0 2 2 2 1 Yeast PIR protein repeat DUF4685 PF15737.5 CCD23051.1 - 0.16 12.4 2.4 0.24 11.9 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) RAP1 PF07218.11 CCD23051.1 - 0.73 8.0 7.9 0.88 7.8 7.9 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sporozoite_P67 PF05642.11 CCD23051.1 - 4.1 5.4 13.8 4.9 5.1 13.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SR-25 PF10500.9 CCD23051.1 - 4.9 6.7 12.4 6.9 6.2 12.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PIR PF00399.19 CCD23052.1 - 2.9e-52 173.2 98.1 2e-08 33.6 9.4 7.9 7 0 0 7 7 7 7 Yeast PIR protein repeat TFIIA PF03153.13 CCD23052.1 - 0.072 13.1 18.5 0.085 12.8 18.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2072 PF09845.9 CCD23052.1 - 6.5 7.0 6.5 55 4.0 6.6 2.2 1 1 0 1 1 1 0 Zn-ribbon containing protein PIR PF00399.19 CCD23053.1 - 4.5e-97 315.9 170.4 9e-09 34.7 6.2 12.9 13 0 0 13 13 13 12 Yeast PIR protein repeat HTH_37 PF13744.6 CCD23053.1 - 0.007 16.3 11.9 24 5.0 0.0 6.2 1 1 7 8 8 8 2 Helix-turn-helix domain DUF4097 PF13349.6 CCD23053.1 - 0.43 9.9 34.6 0.14 11.4 12.8 2.2 1 1 1 2 2 2 0 Putative adhesin DnaJ PF00226.31 CCD23054.1 - 9.6e-18 64.1 0.5 3e-17 62.5 0.5 2.0 1 0 0 1 1 1 1 DnaJ domain DUF2277 PF10041.9 CCD23054.1 - 0.0074 16.6 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2277) Pkinase PF00069.25 CCD23055.1 - 8e-71 238.5 0.0 1.1e-70 238.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23055.1 - 1.1e-39 136.2 0.0 1.7e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD23055.1 - 4.9e-05 22.8 0.0 0.00014 21.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CCD23055.1 - 0.049 12.6 0.1 0.076 11.9 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CCD23055.1 - 0.14 12.1 1.3 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pex14_N PF04695.13 CCD23055.1 - 0.21 12.2 5.9 0.41 11.3 5.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.25 CCD23056.1 - 2.3e-44 151.7 0.5 4.6e-44 150.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23056.1 - 1.5e-18 67.0 0.0 3.2e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CCD23056.1 - 0.029 13.7 0.1 0.064 12.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCD23056.1 - 0.096 12.6 0.2 0.27 11.1 0.2 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family CAP PF00188.26 CCD23057.1 - 5.5e-18 66.0 0.5 3.2e-17 63.5 0.5 2.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family UcrQ PF02939.16 CCD23058.1 - 6.3e-33 112.5 2.1 7.3e-33 112.4 2.1 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 CCD23058.1 - 5.4e-05 23.5 0.1 7.8e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 Ebp2 PF05890.12 CCD23059.1 - 3.7e-89 298.8 32.1 3.7e-89 298.8 32.1 3.0 1 1 2 3 3 3 1 Eukaryotic rRNA processing protein EBP2 SRI PF08236.11 CCD23060.1 - 5.1e-23 81.0 5.0 5.1e-23 81.0 5.0 2.6 3 0 0 3 3 3 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 CCD23060.1 - 6.6e-18 65.7 0.3 6.6e-18 65.7 0.3 4.3 3 2 0 3 3 3 1 SET domain WW_1 PF18507.1 CCD23060.1 - 9.7e-16 57.2 0.5 2.9e-15 55.6 0.1 2.1 2 0 0 2 2 2 1 WW domain AWS PF17907.1 CCD23060.1 - 8.7e-15 54.5 10.1 8.7e-15 54.5 10.1 2.0 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 CCD23060.1 - 0.019 15.0 0.1 0.067 13.2 0.1 2.0 1 0 0 1 1 1 0 TFIIS helical bundle-like domain RIFIN PF02009.16 CCD23061.1 - 0.0013 18.8 1.2 0.0023 17.9 1.2 1.4 1 0 0 1 1 1 1 Rifin Tetraspanin PF00335.20 CCD23061.1 - 0.051 13.3 0.2 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Tetraspanin family Virul_fac_BrkB PF03631.15 CCD23061.1 - 0.081 12.5 0.0 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 Virulence factor BrkB Arc_PepC_II PF06847.11 CCD23061.1 - 0.14 12.7 0.0 0.14 12.7 0.0 2.4 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Sigma_reg_N PF13800.6 CCD23061.1 - 0.32 11.3 3.1 2.9 8.2 1.3 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Peptidase_M20 PF01546.28 CCD23062.1 - 6e-36 124.1 0.0 7.7e-30 104.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CCD23062.1 - 3.8e-13 49.3 0.0 9.6e-13 48.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Rep_fac-A_3 PF08661.11 CCD23063.1 - 2.6e-28 98.4 0.0 3e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 KRE9 PF05390.11 CCD23064.1 - 5.4e-47 158.7 9.6 5.4e-47 158.7 9.6 2.2 3 0 0 3 3 3 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 CCD23064.1 - 1.7e-14 54.4 1.6 1.7e-14 54.4 1.6 2.5 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SWIRM PF04433.17 CCD23065.1 - 4.5e-28 97.4 1.5 1.2e-27 96.0 0.3 2.4 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 CCD23065.1 - 5.9e-19 67.8 10.8 6.1e-19 67.8 9.1 2.0 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 CCD23065.1 - 2.5e-11 43.6 0.0 7.1e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCD23065.1 - 7.1e-07 29.4 0.2 2.1e-06 27.8 0.2 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ribosomal_L22 PF00237.19 CCD23066.1 - 5.5e-38 129.3 0.2 5.5e-38 129.3 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e CRT10 PF08728.10 CCD23066.1 - 0.069 11.3 0.2 0.072 11.3 0.2 1.0 1 0 0 1 1 1 0 CRT10 Fis1_TPR_C PF14853.6 CCD23066.1 - 0.078 13.1 0.1 25 5.1 0.0 2.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ATG27 PF09451.10 CCD23067.1 - 3.9e-52 177.7 1.9 5.8e-52 177.1 1.9 1.2 1 1 0 1 1 1 1 Autophagy-related protein 27 PBP1_TM PF14812.6 CCD23067.1 - 4.7e-05 23.7 1.4 8.7e-05 22.8 1.4 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Orf78 PF06024.12 CCD23067.1 - 0.006 16.9 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Orf78 (ac78) Prefoldin_2 PF01920.20 CCD23068.1 - 1.6e-11 44.1 12.8 2.1e-11 43.7 12.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF4568 PF15132.6 CCD23068.1 - 0.015 14.7 0.5 0.019 14.4 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) APG6_N PF17675.1 CCD23068.1 - 0.091 13.3 8.3 0.12 12.9 8.3 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 CCD23068.1 - 1.3 9.7 10.1 8.8 7.0 2.7 2.7 2 1 1 3 3 3 0 SlyX ATP12 PF07542.11 CCD23069.1 - 1.9e-30 105.6 0.0 3.7e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein Glyco_transf_34 PF05637.12 CCD23070.1 - 4.6e-58 196.8 0.1 6.3e-58 196.3 0.1 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Gon7 PF08738.10 CCD23071.1 - 6.5e-43 145.2 0.3 7.9e-43 144.9 0.3 1.1 1 0 0 1 1 1 1 Gon7 family NUC153 PF08159.12 CCD23071.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 NUC153 domain Spore_Cse60 PF10957.8 CCD23071.1 - 0.073 13.1 2.4 1.2 9.2 0.8 2.3 2 0 0 2 2 2 0 Sporulation protein Cse60 muHD PF10291.9 CCD23073.1 - 2.8e-64 217.1 0.1 9.2e-64 215.4 0.1 1.9 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain DUF2397 PF09660.10 CCD23073.1 - 0.0014 17.7 1.1 0.0014 17.7 1.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2397) Pkinase PF00069.25 CCD23074.1 - 4.5e-48 163.9 1.5 1e-47 162.7 1.5 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23074.1 - 3.4e-27 95.4 0.1 7e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD23074.1 - 0.022 14.1 0.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Ribosomal_L39 PF00832.20 CCD23075.1 - 1.9e-21 75.4 12.6 2.3e-21 75.1 12.6 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Ribosomal_S8 PF00410.19 CCD23076.1 - 3e-24 85.4 0.2 4.7e-24 84.7 0.2 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S11 PF00411.19 CCD23077.1 - 5.1e-46 155.6 2.3 6.3e-46 155.3 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 SOP4 PF17081.5 CCD23078.1 - 3.2e-99 330.6 1.2 3.7e-99 330.4 1.2 1.0 1 0 0 1 1 1 1 Suppressor of PMA 1-7 protein TPT PF03151.16 CCD23079.1 - 7.5e-32 110.8 17.9 2.7e-17 63.1 0.7 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 CCD23079.1 - 0.00058 20.0 32.1 0.016 15.4 13.1 4.7 4 1 1 5 5 5 3 EamA-like transporter family DUF3611 PF12263.8 CCD23079.1 - 0.035 14.0 3.5 3.4 7.5 0.4 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3611) SLATT_5 PF18160.1 CCD23079.1 - 0.13 11.5 4.5 0.26 10.6 1.5 2.5 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 AAA_22 PF13401.6 CCD23080.1 - 1.9e-09 37.9 0.0 7.7e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CCD23080.1 - 1.6e-08 35.0 0.0 6.5e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 CCD23080.1 - 2.5e-07 30.6 0.1 5.9e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_16 PF13191.6 CCD23080.1 - 7.8e-07 29.6 0.0 3.7e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 CCD23080.1 - 0.0039 16.6 0.1 0.24 10.8 0.1 2.3 1 1 0 1 1 1 1 Bacterial TniB protein AAA_19 PF13245.6 CCD23080.1 - 0.0053 17.1 0.6 0.058 13.7 0.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CCD23080.1 - 0.0077 15.8 0.1 0.95 9.0 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_5 PF07728.14 CCD23080.1 - 0.019 14.9 0.2 10 6.1 0.0 3.7 3 1 1 4 4 4 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 CCD23080.1 - 0.029 14.2 0.2 0.093 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CCD23080.1 - 0.045 13.7 0.0 0.28 11.1 0.0 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 CCD23080.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 CCD23080.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Myb_DNA-binding PF00249.31 CCD23081.1 - 9.2e-05 22.6 0.0 0.00024 21.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Med28 PF11594.8 CCD23081.1 - 0.057 13.5 0.8 0.14 12.3 0.2 2.0 2 0 0 2 2 2 0 Mediator complex subunit 28 UCH PF00443.29 CCD23082.1 - 4.1e-76 255.9 0.0 4.2e-75 252.6 0.0 2.7 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCD23082.1 - 2.6e-15 56.8 12.1 6.7e-08 32.5 1.9 3.8 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CCD23082.1 - 1.2e-09 38.7 0.2 1.1e-08 35.5 0.2 2.8 1 0 0 1 1 1 1 DUSP domain ubiquitin PF00240.23 CCD23082.1 - 0.0042 16.8 0.3 5.1 6.9 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin family TF_Zn_Ribbon PF08271.12 CCD23082.1 - 2.3 7.8 6.0 0.84 9.2 0.4 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding SPX PF03105.19 CCD23083.1 - 2e-51 176.1 18.9 2.6e-51 175.7 18.9 1.1 1 0 0 1 1 1 1 SPX domain CitMHS PF03600.16 CCD23083.1 - 1.8e-30 106.2 56.4 2.1e-25 89.6 35.1 2.1 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 CCD23083.1 - 4.6e-21 75.4 33.5 6.1e-21 75.0 33.5 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CENP-B_dimeris PF09026.10 CCD23083.1 - 1.1 9.7 7.1 1.2 9.5 3.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sir1 PF11603.8 CCD23086.1 - 9.2e-14 52.0 0.6 3.6e-13 50.0 0.6 2.1 1 0 0 1 1 1 1 Regulatory protein Sir1 DEAD PF00270.29 CCD23086.1 - 5.7e-09 36.0 0.0 5.4e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase mTERF PF02536.14 CCD23086.1 - 0.03 13.3 0.3 0.05 12.5 0.3 1.2 1 0 0 1 1 1 0 mTERF ResIII PF04851.15 CCD23086.1 - 0.11 12.5 0.0 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 CCD23087.1 - 3.3e-08 33.5 0.0 3.2e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase mTERF PF02536.14 CCD23087.1 - 0.048 12.6 0.2 0.079 11.9 0.2 1.3 1 0 0 1 1 1 0 mTERF ResIII PF04851.15 CCD23087.1 - 0.19 11.7 0.0 0.67 9.9 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF5341 PF17276.2 CCD23089.1 - 5.9e-05 23.3 0.0 7.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5341) Ogr_Delta PF04606.12 CCD23089.1 - 0.24 11.4 0.7 0.55 10.3 0.1 1.8 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Cys_Met_Meta_PP PF01053.20 CCD23093.1 - 2.2e-52 177.9 0.1 6.4e-52 176.3 0.1 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CCD23093.1 - 0.00024 20.2 0.0 0.00043 19.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V CTP_transf_like PF01467.26 CCD23094.1 - 2.5e-09 37.5 0.1 8.6e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase-like MA3 PF02847.17 CCD23095.1 - 7.7e-18 64.5 1.8 3e-17 62.6 0.0 2.8 3 0 0 3 3 3 1 MA3 domain MIF4G PF02854.19 CCD23095.1 - 1.6e-07 31.2 8.3 1.6e-07 31.2 8.3 2.3 2 0 0 2 2 2 1 MIF4G domain MNE1 PF13762.6 CCD23095.1 - 0.0067 16.4 3.4 0.0067 16.4 3.4 4.0 4 0 0 4 4 4 1 Mitochondrial splicing apparatus component Pox_polyA_pol_N PF12630.7 CCD23095.1 - 0.77 10.1 4.6 8 6.9 0.5 3.5 2 1 1 3 3 3 0 Poxvirus poly(A) polymerase N-terminal domain Myb_DNA-bind_3 PF12776.7 CCD23095.1 - 1.5 9.9 4.1 20 6.2 0.2 3.7 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain Glyco_hydro_17 PF00332.18 CCD23096.1 - 1.7e-10 41.0 1.4 1.7e-10 41.0 1.4 2.4 2 1 1 3 3 3 1 Glycosyl hydrolases family 17 G-patch PF01585.23 CCD23097.1 - 1.4e-12 47.3 0.2 3.4e-12 46.0 0.2 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CCD23097.1 - 0.0034 17.5 0.1 0.0034 17.5 0.1 3.8 2 1 1 3 3 3 1 G-patch domain Sigma70_ner PF04546.13 CCD23097.1 - 0.0036 17.2 18.3 0.0051 16.7 18.3 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region CDC45 PF02724.14 CCD23097.1 - 0.0056 15.1 28.4 0.0073 14.7 28.4 1.1 1 0 0 1 1 1 1 CDC45-like protein TFIIF_alpha PF05793.12 CCD23097.1 - 0.0095 14.6 39.1 0.013 14.1 39.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DIRP PF06584.13 CCD23097.1 - 0.16 12.1 10.7 0.3 11.3 10.7 1.4 1 0 0 1 1 1 0 DIRP RRN3 PF05327.11 CCD23097.1 - 0.31 9.5 15.1 0.38 9.2 15.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NAM-associated PF14303.6 CCD23097.1 - 1.4 9.6 37.1 0.76 10.5 33.5 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain GREB1 PF15782.5 CCD23097.1 - 3.1 4.8 15.4 3.8 4.5 15.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 CCD23097.1 - 3.3 6.6 20.0 4.3 6.3 20.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Hydin_ADK PF17213.3 CCD23097.1 - 4.4 7.5 10.4 6.7 6.9 10.4 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Hid1 PF12722.7 CCD23097.1 - 4.4 5.3 23.9 5.8 4.9 23.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ABC_membrane PF00664.23 CCD23098.1 - 1.9e-82 277.0 40.6 2e-47 162.1 13.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CCD23098.1 - 2.9e-47 160.6 5.7 4.2e-29 101.8 0.1 3.9 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.19 CCD23098.1 - 8.3e-10 38.5 0.1 0.0097 15.4 0.0 4.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CCD23098.1 - 1.7e-07 31.4 9.8 0.031 14.1 0.0 5.7 6 1 1 7 7 6 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCD23098.1 - 1.2e-06 28.1 1.4 0.037 13.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCD23098.1 - 1.5e-05 25.0 0.7 0.049 13.5 0.2 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 CCD23098.1 - 6.3e-05 23.5 1.8 0.033 14.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 CCD23098.1 - 7.8e-05 23.0 0.5 1.8 8.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 CCD23098.1 - 9.4e-05 21.6 0.0 0.0077 15.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 CCD23098.1 - 0.00012 22.2 0.7 0.11 12.6 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 CCD23098.1 - 0.00019 22.0 6.4 0.0034 17.9 4.1 4.3 3 1 1 4 4 3 2 AAA domain AAA_30 PF13604.6 CCD23098.1 - 0.00042 20.1 0.7 0.55 9.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 CCD23098.1 - 0.0016 17.8 0.0 0.12 11.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 CCD23098.1 - 0.0018 17.9 0.1 1.8 8.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region ATP_bind_1 PF03029.17 CCD23098.1 - 0.0057 16.5 0.0 6.2 6.5 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 CCD23098.1 - 0.015 15.4 0.0 3.2 7.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CCD23098.1 - 0.016 15.0 0.5 3.4 7.3 0.0 3.0 3 0 0 3 3 2 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 CCD23098.1 - 0.016 14.6 0.2 5.1 6.4 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.14 CCD23098.1 - 0.016 15.2 0.2 3.4 7.7 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 CCD23098.1 - 0.018 14.9 8.5 0.018 14.9 0.0 3.5 3 1 1 4 4 2 0 AAA domain RNA_helicase PF00910.22 CCD23098.1 - 0.018 15.5 0.1 17 5.8 0.0 3.7 4 0 0 4 4 3 0 RNA helicase TsaE PF02367.17 CCD23098.1 - 0.022 14.8 0.4 0.72 9.9 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 CCD23098.1 - 0.023 14.5 0.3 10 5.9 0.0 3.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 CCD23098.1 - 0.026 14.9 1.5 0.45 10.9 0.0 3.5 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 CCD23098.1 - 0.034 13.7 0.2 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CCD23098.1 - 0.047 14.1 0.1 2.3 8.6 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 CCD23098.1 - 0.077 12.6 0.2 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CCD23098.1 - 0.1 12.8 0.3 19 5.5 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 CCD23098.1 - 0.1 12.8 0.5 3.8 7.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 CCD23098.1 - 0.16 11.6 0.2 2.4 7.7 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 CCD23098.1 - 0.17 12.0 0.0 0.17 12.0 0.0 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain Dynamin_N PF00350.23 CCD23098.1 - 0.18 11.8 11.2 0.54 10.3 0.0 4.0 4 0 0 4 4 3 0 Dynamin family AAA_27 PF13514.6 CCD23098.1 - 0.5 9.9 4.4 3.1 7.3 0.1 2.8 3 0 0 3 3 2 0 AAA domain Glyco_hydro_17 PF00332.18 CCD23099.1 - 2.5e-87 293.4 4.5 2.9e-87 293.2 4.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 SURF4 PF02077.15 CCD23100.1 - 5.2e-96 321.3 14.2 6.4e-96 321.0 14.2 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 CCD23100.1 - 0.14 12.7 15.3 1.5 9.5 6.0 3.4 2 1 1 3 3 3 0 DoxX S_4TM PF18159.1 CCD23100.1 - 0.27 10.5 3.7 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain MerC PF03203.14 CCD23100.1 - 1.2 9.6 13.1 0.26 11.7 3.6 2.4 1 1 1 2 2 2 0 MerC mercury resistance protein RAC_head PF16717.5 CCD23101.1 - 6.3e-21 75.2 1.8 6.3e-21 75.2 1.8 3.5 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 CCD23101.1 - 2.6e-16 59.5 0.3 9.3e-16 57.7 0.3 2.1 1 0 0 1 1 1 1 DnaJ domain V_ATPase_I PF01496.19 CCD23101.1 - 4.3 5.1 7.4 6.1 4.6 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 CCD23101.1 - 5.3 6.0 11.4 11 4.9 11.4 1.6 1 0 0 1 1 1 0 Solute carrier family 12 Hyphal_reg_CWP PF11765.8 CCD23102.1 - 4.8e-36 124.3 27.5 1e-35 123.2 27.5 1.5 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal DUF5559 PF17714.1 CCD23102.1 - 0.00026 20.9 0.0 9 6.1 0.0 4.6 2 2 3 5 5 5 2 Family of unknown function (DUF5559) RNase_T PF00929.24 CCD23103.1 - 7.5e-10 39.6 0.0 1.7e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 Exonuclease Rtt102p PF09510.10 CCD23104.1 - 2.6e-45 153.9 1.7 2.6e-45 153.9 1.7 2.5 2 1 0 2 2 2 1 Rtt102p-like transcription regulator protein Lipocalin_2 PF08212.12 CCD23104.1 - 0.18 11.7 0.9 0.27 11.2 0.1 1.7 2 0 0 2 2 2 0 Lipocalin-like domain DDE_1 PF03184.19 CCD23105.1 - 4e-07 29.8 0.3 1.9e-06 27.7 0.3 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF5345 PF17280.2 CCD23106.1 - 0.14 12.2 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5345) DUF2406 PF10295.9 CCD23107.1 - 6.4e-24 84.4 0.1 1.2e-23 83.6 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) zf-C2H2_10 PF16588.5 CCD23108.1 - 1.3e-05 24.8 2.4 2.4e-05 24.0 2.4 1.4 1 0 0 1 1 1 1 C2H2 zinc-finger gag_pre-integrs PF13976.6 CCD23108.1 - 0.0062 16.4 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC_4 PF14392.6 CCD23108.1 - 0.35 10.6 1.2 0.93 9.3 1.2 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.14 CCD23109.1 - 1.6e-05 24.7 0.3 2.7e-05 23.9 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CCD23109.1 - 0.0093 15.5 0.3 0.12 11.8 0.1 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Efg1 PF10153.9 CCD23110.1 - 6.6e-34 116.7 15.1 6.6e-34 116.7 15.1 2.5 3 0 0 3 3 3 1 rRNA-processing protein Efg1 PWWP PF00855.17 CCD23110.1 - 4.4 7.8 5.8 5.1 7.6 0.9 2.5 1 1 1 2 2 2 0 PWWP domain Sec63 PF02889.16 CCD23111.1 - 1.1e-120 401.6 0.7 1.1e-80 270.5 0.0 2.6 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CCD23111.1 - 6.5e-50 169.3 0.5 1.6e-25 89.9 0.5 3.8 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 CCD23111.1 - 5.4e-30 104.6 0.0 1.3e-14 54.6 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCD23111.1 - 6.6e-20 71.5 0.1 1.2e-08 35.3 0.0 4.3 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA PF00004.29 CCD23111.1 - 3e-06 27.7 2.2 0.43 11.0 0.0 4.6 4 2 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCD23111.1 - 2.9e-05 24.4 8.7 0.12 12.7 0.3 5.5 4 3 0 4 4 3 2 AAA domain PhoH PF02562.16 CCD23111.1 - 0.00011 21.7 0.0 0.071 12.5 0.0 2.8 2 0 0 2 2 2 2 PhoH-like protein IstB_IS21 PF01695.17 CCD23111.1 - 0.00011 21.9 0.1 0.34 10.6 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein T2SSE PF00437.20 CCD23111.1 - 0.00063 18.9 0.0 0.25 10.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.6 CCD23111.1 - 0.0016 18.8 0.1 0.62 10.4 0.2 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCD23111.1 - 0.029 14.8 0.0 4.2 7.7 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain MotA_ExbB PF01618.16 CCD23111.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family TniB PF05621.11 CCD23111.1 - 0.31 10.4 2.5 22 4.4 0.0 3.7 4 0 0 4 4 4 0 Bacterial TniB protein AAA PF00004.29 CCD23112.1 - 1.3e-51 174.4 0.0 1.2e-42 145.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCD23112.1 - 4.6e-10 39.1 0.0 1.2e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CCD23112.1 - 3.8e-07 30.4 0.0 2.6e-05 24.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CCD23112.1 - 2e-06 27.7 0.0 0.00014 21.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 CCD23112.1 - 9.6e-06 26.1 0.2 0.00016 22.1 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CCD23112.1 - 2.3e-05 24.4 0.0 0.00092 19.2 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 CCD23112.1 - 3.3e-05 24.0 0.0 0.44 10.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain TIP49 PF06068.13 CCD23112.1 - 0.0002 20.7 0.0 0.022 14.0 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain ResIII PF04851.15 CCD23112.1 - 0.00024 21.2 0.0 0.0056 16.7 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 CCD23112.1 - 0.00038 20.2 0.0 0.68 9.6 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 CCD23112.1 - 0.00043 20.6 1.8 0.15 12.4 0.2 4.4 3 2 1 4 4 4 1 AAA domain AAA_7 PF12775.7 CCD23112.1 - 0.00088 18.8 0.0 0.2 11.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 CCD23112.1 - 0.0048 16.9 0.0 0.038 14.0 0.0 2.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CCD23112.1 - 0.0073 15.7 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CCD23112.1 - 0.0094 16.3 0.0 0.051 14.0 0.0 2.3 3 0 0 3 3 1 1 RNA helicase AAA_18 PF13238.6 CCD23112.1 - 0.0098 16.4 0.2 0.19 12.3 0.0 3.5 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 CCD23112.1 - 0.012 16.1 6.5 0.042 14.4 0.0 3.8 4 0 0 4 4 3 0 ABC transporter PhoH PF02562.16 CCD23112.1 - 0.021 14.3 0.0 0.31 10.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 CCD23112.1 - 0.023 14.9 0.0 0.079 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CCD23112.1 - 0.037 13.9 0.1 0.099 12.5 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 CCD23112.1 - 0.059 12.5 0.0 0.75 8.8 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 RuvB_N PF05496.12 CCD23112.1 - 0.068 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 CCD23112.1 - 0.071 12.7 0.0 0.3 10.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain Bromodomain PF00439.25 CCD23112.1 - 0.089 12.9 1.9 0.15 12.2 0.1 2.3 3 0 0 3 3 1 0 Bromodomain AAA_11 PF13086.6 CCD23112.1 - 0.51 10.1 0.0 0.51 10.1 0.0 4.2 4 2 0 4 4 2 0 AAA domain DnaJ_CXXCXGXG PF00684.19 CCD23113.1 - 0.00065 20.0 10.4 0.059 13.7 0.7 2.6 3 0 0 3 3 3 2 DnaJ central domain TMEM51 PF15345.6 CCD23113.1 - 0.063 13.1 1.1 0.093 12.6 1.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 SUIM_assoc PF16619.5 CCD23113.1 - 0.23 11.6 8.3 0.5 10.5 8.3 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 HypA PF01155.19 CCD23113.1 - 0.29 11.2 1.5 3.7 7.6 0.5 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CCDC53 PF10152.9 CCD23113.1 - 5 7.5 6.7 7.5 7.0 6.7 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Anti-TRAP PF15777.5 CCD23113.1 - 5.7 7.0 10.9 1.2 9.1 0.9 3.3 2 2 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein GTP_cyclohydroI PF01227.22 CCD23114.1 - 1e-76 256.3 0.7 1.2e-76 256.1 0.7 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 CCD23114.1 - 1.2e-05 25.3 0.0 4.7e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein PhoD PF09423.10 CCD23115.1 - 0.0072 15.4 0.0 0.044 12.8 0.0 2.3 1 1 0 1 1 1 1 PhoD-like phosphatase Say1_Mug180 PF10340.9 CCD23116.1 - 8.9e-95 317.7 2.6 1e-94 317.5 2.6 1.0 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 CCD23116.1 - 2.7e-13 50.3 0.0 3.6e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CCD23117.1 - 2.2e-86 290.1 0.0 2.5e-86 289.9 0.0 1.0 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 CCD23117.1 - 1.3e-15 57.8 0.0 1.7e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Kdo PF06293.14 CCD23118.1 - 7.2e-07 28.8 0.0 1.3e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CCD23118.1 - 0.0001 22.0 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 CCD23118.1 - 0.00054 19.4 0.0 0.00072 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23118.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF1679 PF07914.11 CCD23118.1 - 0.16 10.8 0.1 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 CCD23118.1 - 0.2 10.9 0.6 0.74 9.1 0.1 2.0 2 1 0 2 2 2 0 Ecdysteroid kinase Adaptin_N PF01602.20 CCD23119.1 - 1.6e-99 333.8 8.3 2e-99 333.6 8.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CCD23119.1 - 3.5e-11 43.4 8.0 8.5e-11 42.2 0.0 4.2 3 2 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCD23119.1 - 6.6e-08 32.8 0.1 1.1e-06 28.9 0.0 2.9 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 CCD23119.1 - 2e-06 27.5 0.5 0.041 14.1 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 CCD23119.1 - 0.0006 20.3 0.0 0.52 10.9 0.0 3.9 4 0 0 4 4 4 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CCD23119.1 - 0.015 15.8 1.1 0.96 10.1 0.0 3.8 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 CCD23119.1 - 0.025 14.6 0.1 0.23 11.4 0.0 2.6 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 CCD23119.1 - 0.046 13.3 0.6 14 5.2 0.0 3.2 2 1 1 3 3 3 0 CLASP N terminal TFIIA PF03153.13 CCD23119.1 - 1.1 9.2 11.9 1.8 8.5 11.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Na_trans_assoc PF06512.13 CCD23119.1 - 6.4 7.0 13.2 14 5.9 13.2 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated Sigma70_ner PF04546.13 CCD23119.1 - 6.4 6.6 12.5 14 5.5 12.5 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 CCD23119.1 - 9.2 5.9 15.9 16 5.1 15.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MFS_1 PF07690.16 CCD23120.1 - 2.6e-30 105.6 28.1 2.7e-30 105.5 27.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_C26 PF07722.13 CCD23120.1 - 0.25 11.1 1.1 0.46 10.2 0.1 1.8 2 0 0 2 2 2 0 Peptidase C26 XPG_N PF00752.17 CCD23121.1 - 2e-35 121.3 0.0 5e-35 120.0 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CCD23121.1 - 2.1e-24 85.7 0.0 1.4e-23 83.0 0.0 2.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CCD23121.1 - 0.0045 17.6 3.4 0.01 16.4 0.0 3.2 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold Mito_carr PF00153.27 CCD23122.1 - 5.9e-61 202.4 4.1 9.9e-22 76.7 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein NOP19 PF10863.8 CCD23123.1 - 2.6e-59 199.1 8.7 2.6e-59 199.1 8.7 1.9 2 0 0 2 2 2 1 Nucleolar protein 19 C_LFY_FLO PF17538.2 CCD23123.1 - 0.012 15.1 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 DNA Binding Domain (C-terminal) Leafy/Floricaula Gar1 PF04410.14 CCD23123.1 - 6.5 6.5 8.4 0.4 10.4 3.0 1.7 2 0 0 2 2 2 0 Gar1/Naf1 RNA binding region DEAD PF00270.29 CCD23124.1 - 1.7e-41 141.9 0.0 4.4e-41 140.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD23124.1 - 3.9e-29 101.2 0.0 2.9e-28 98.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD23124.1 - 0.00033 20.7 0.0 0.00081 19.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Engrail_1_C_sig PF10525.9 CCD23125.1 - 0.1 11.8 0.2 0.24 10.7 0.2 1.5 1 0 0 1 1 1 0 Engrailed homeobox C-terminal signature domain Peptidase_S41_N PF11918.8 CCD23125.1 - 0.51 10.6 2.0 12 6.2 0.1 2.7 2 1 0 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Oxidored_FMN PF00724.20 CCD23126.1 - 1e-128 429.4 0.0 1.2e-128 429.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RRM_1 PF00076.22 CCD23127.1 - 4.3e-26 90.5 1.1 1.5e-07 31.2 0.2 5.7 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD23127.1 - 0.0024 18.0 0.0 0.4 10.8 0.0 3.7 4 0 0 4 4 4 1 RNA recognition motif HSF_DNA-bind PF00447.17 CCD23128.1 - 1.7e-21 76.7 2.8 6.1e-21 74.8 2.8 2.1 1 0 0 1 1 1 1 HSF-type DNA-binding Glucosamine_iso PF01182.20 CCD23129.1 - 6e-07 29.6 0.0 8.9e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CPDase PF07823.11 CCD23130.1 - 1.4e-73 246.9 0.4 1.7e-73 246.6 0.4 1.1 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 CCD23130.1 - 0.0026 17.7 0.0 0.006 16.5 0.0 1.7 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily TFIIB PF00382.19 CCD23131.1 - 6.6e-55 183.1 0.7 1.3e-27 95.6 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 CCD23131.1 - 6.1e-30 103.5 3.0 6.1e-30 103.5 3.0 3.2 2 1 1 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 CCD23131.1 - 3e-10 39.4 2.9 6.9e-10 38.3 2.9 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 CCD23131.1 - 0.001 18.8 0.1 0.83 9.4 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain SDA1 PF05285.12 CCD23132.1 - 2.9e-101 339.4 37.0 2.9e-101 339.4 37.0 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 CCD23132.1 - 7.5e-19 67.8 0.3 1.7e-18 66.7 0.3 1.7 1 0 0 1 1 1 1 NUC130/3NT domain YL1 PF05764.13 CCD23132.1 - 6.1 6.9 45.3 7 6.7 1.6 2.6 2 1 0 2 2 2 0 YL1 nuclear protein ATP-grasp_2 PF08442.10 CCD23133.1 - 9.6e-68 227.7 0.3 1.8e-67 226.9 0.3 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CCD23133.1 - 4.8e-26 91.4 0.1 8.8e-26 90.5 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 CCD23133.1 - 2.9e-06 26.9 0.0 5.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 CCD23133.1 - 0.0021 17.9 0.2 0.0048 16.7 0.2 1.6 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.18 CCD23133.1 - 0.11 12.8 0.2 6.5 7.1 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain PTS_IIB PF02302.17 CCD23133.1 - 0.26 12.0 1.5 1.6 9.5 0.2 2.7 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit MPC PF03650.13 CCD23134.1 - 3.9e-49 165.4 0.2 4.8e-49 165.1 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Aim21 PF11489.8 CCD23135.1 - 6.9e-12 45.1 58.6 6.9e-12 45.1 58.6 3.0 2 1 0 3 3 3 1 Altered inheritance of mitochondria protein 21 DUF2730 PF10805.8 CCD23135.1 - 1.4 9.0 4.3 3.6 7.8 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) ResIII PF04851.15 CCD23136.1 - 5.5e-20 72.0 0.0 5.5e-20 72.0 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCD23136.1 - 6.3e-19 68.4 1.6 1.3e-17 64.1 0.2 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCD23136.1 - 1.2e-17 64.3 0.0 5.1e-17 62.2 0.0 2.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase LRR_8 PF13855.6 CCD23137.1 - 3.2e-14 52.4 21.6 5.4e-09 35.7 3.3 4.8 3 2 1 5 5 5 4 Leucine rich repeat CAP_GLY PF01302.25 CCD23137.1 - 4.6e-12 45.8 0.0 8.6e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 CCD23137.1 - 1.6e-10 41.0 37.3 0.00089 19.6 1.5 5.9 1 1 7 8 8 8 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CCD23137.1 - 7.2e-07 28.8 27.0 1.9 8.8 0.1 9.0 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.33 CCD23137.1 - 0.00026 21.1 35.1 0.67 10.7 0.1 9.4 8 1 1 9 9 9 3 Leucine Rich Repeat Nas2_N PF18265.1 CCD23138.1 - 9.3e-21 73.6 0.4 1.4e-20 73.0 0.4 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain GRASP55_65 PF04495.14 CCD23138.1 - 0.00021 21.6 0.0 0.00038 20.8 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 CCD23138.1 - 0.00026 21.3 0.2 0.00046 20.5 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CCD23138.1 - 0.0028 17.5 0.4 0.0047 16.7 0.4 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CCD23138.1 - 0.04 14.3 0.1 0.078 13.3 0.1 1.5 1 0 0 1 1 1 0 PDZ domain Gti1_Pac2 PF09729.9 CCD23139.1 - 2.2e-45 155.0 2.3 1.8e-44 152.0 0.3 2.9 2 1 0 2 2 2 1 Gti1/Pac2 family Mito_carr PF00153.27 CCD23140.1 - 1.8e-69 229.7 3.2 5.7e-23 80.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CCD23140.1 - 0.11 11.6 0.5 1.6 7.8 0.0 2.8 1 1 2 3 3 3 0 Gammaproteobacterial serine protease Thioredoxin PF00085.20 CCD23141.1 - 4.9e-27 93.9 1.1 1.1e-21 76.7 0.0 4.4 3 2 1 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 CCD23141.1 - 0.00021 21.3 5.5 0.00092 19.2 0.3 3.5 2 1 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CCD23141.1 - 0.0029 18.1 0.2 0.32 11.5 0.0 2.9 2 0 0 2 2 2 1 Thioredoxin-like domain MCM6_C PF18263.1 CCD23141.1 - 0.014 15.6 1.3 0.034 14.4 1.3 1.6 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Use1 PF09753.9 CCD23142.1 - 9e-08 32.1 0.5 1.1e-07 31.8 0.5 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sec20 PF03908.13 CCD23142.1 - 0.19 11.7 3.0 0.23 11.4 0.9 1.9 1 1 1 2 2 2 0 Sec20 Syja_N PF02383.18 CCD23143.1 - 3.3e-45 154.8 0.9 4.8e-45 154.2 0.2 1.6 1 1 1 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 CCD23143.1 - 2.4e-11 43.6 0.0 3.6e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HSBP1 PF06825.12 CCD23144.1 - 9.5e-05 22.2 3.7 0.0002 21.1 3.7 1.5 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Laminin_II PF06009.12 CCD23144.1 - 0.00031 20.8 1.1 0.00034 20.7 1.1 1.1 1 0 0 1 1 1 1 Laminin Domain II APG6_N PF17675.1 CCD23144.1 - 0.002 18.7 2.5 0.002 18.7 2.5 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region Spectrin PF00435.21 CCD23144.1 - 0.0043 17.5 1.7 0.0049 17.3 1.7 1.2 1 0 0 1 1 1 1 Spectrin repeat Chlamy_scaf PF09675.10 CCD23144.1 - 0.02 15.2 0.1 0.023 15.0 0.1 1.1 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) Prefoldin PF02996.17 CCD23144.1 - 0.025 14.5 1.9 0.035 14.0 1.9 1.3 1 0 0 1 1 1 0 Prefoldin subunit FlaC_arch PF05377.11 CCD23144.1 - 0.031 14.7 1.8 0.059 13.8 1.8 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 CCD23144.1 - 0.041 14.2 0.2 0.051 13.8 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Helo_like_N PF17111.5 CCD23144.1 - 0.056 12.8 1.6 0.053 12.9 1.6 1.1 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DASH_Dam1 PF08653.10 CCD23144.1 - 0.078 12.8 1.7 0.14 12.0 1.7 1.4 1 0 0 1 1 1 0 DASH complex subunit Dam1 XhlA PF10779.9 CCD23144.1 - 0.085 13.1 2.3 0.12 12.6 2.3 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Spc24 PF08286.11 CCD23144.1 - 0.095 12.9 5.1 0.13 12.5 5.1 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4588 PF15251.6 CCD23145.1 - 3.4e-05 23.7 4.3 4.5e-05 23.4 4.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) DUF713 PF05218.14 CCD23145.1 - 0.0022 17.7 0.6 0.0043 16.8 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF713) GFO_IDH_MocA PF01408.22 CCD23146.1 - 1.2e-05 26.1 0.0 1.9e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CCD23146.1 - 0.00017 21.5 0.0 0.00039 20.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Hit1_C PF18268.1 CCD23147.1 - 1.2e-43 147.1 1.0 1.2e-43 147.1 1.0 1.6 2 0 0 2 2 2 1 Hit1 C-terminal zf-HIT PF04438.16 CCD23147.1 - 6.5e-12 45.1 14.9 8.8e-12 44.7 10.1 2.2 2 0 0 2 2 2 1 HIT zinc finger YL1_C PF08265.11 CCD23147.1 - 0.00036 20.2 0.0 0.00083 19.1 0.0 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Shisa PF13908.6 CCD23147.1 - 0.016 15.5 1.8 0.023 14.9 1.8 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator zf-MYND PF01753.18 CCD23147.1 - 0.024 14.7 7.5 0.024 14.7 7.5 1.8 2 0 0 2 2 2 0 MYND finger zf-Mss51 PF13824.6 CCD23147.1 - 0.035 14.2 4.8 0.076 13.1 4.8 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf_C2H2_6 PF18450.1 CCD23147.1 - 0.089 12.5 5.2 0.072 12.8 3.0 2.1 2 1 0 2 2 2 0 Zinc Finger domain zf-B_box PF00643.24 CCD23147.1 - 0.16 12.2 10.8 0.14 12.3 6.6 2.1 2 0 0 2 2 2 0 B-box zinc finger zf-RING_2 PF13639.6 CCD23147.1 - 0.82 10.1 10.0 11 6.4 6.2 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C6H2 PF15801.5 CCD23147.1 - 1.8 9.0 11.8 0.23 11.8 7.4 1.9 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-CCHC PF00098.23 CCD23148.1 - 0.0016 18.4 2.3 0.0024 17.9 2.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CCD23148.1 - 0.019 14.9 1.1 0.031 14.2 1.1 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 CCD23148.1 - 0.041 13.6 1.3 0.078 12.7 1.3 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-C2H2_10 PF16588.5 CCD23148.1 - 0.053 13.3 1.3 0.089 12.5 1.3 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_4 PF14392.6 CCD23148.1 - 0.097 12.4 0.4 0.17 11.6 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Peptidase_A2B PF12384.8 CCD23149.1 - 2.1e-25 89.3 0.3 3e-25 88.8 0.3 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.6 CCD23149.1 - 2.7e-08 34.3 0.0 5.6e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CCD23149.1 - 1.3e-06 28.9 0.0 2.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CCD23149.1 - 0.0079 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF1758 PF05585.12 CCD23149.1 - 0.056 13.2 0.0 0.093 12.5 0.0 1.5 1 1 0 1 1 1 0 Putative peptidase (DUF1758) Retrotrans_gag PF03732.17 CCD23150.1 - 1.3e-11 44.6 0.0 2.2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_5 PF14787.6 CCD23150.1 - 0.00036 20.2 4.9 0.00083 19.0 4.9 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger DUF4939 PF16297.5 CCD23150.1 - 0.00077 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 CCD23150.1 - 0.004 17.2 1.9 0.0075 16.3 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle Pectate_lyase22 PF14583.6 CCD23150.1 - 0.059 12.0 0.0 0.25 9.9 0.0 1.9 2 1 1 3 3 3 0 Oligogalacturonate lyase DUF962 PF06127.11 CCD23150.1 - 0.15 12.1 0.5 3.8 7.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF962) zf-CCHC_4 PF14392.6 CCD23150.1 - 1.3 8.8 4.1 2.4 7.9 4.1 1.4 1 0 0 1 1 1 0 Zinc knuckle KCH PF16944.5 CCD23151.1 - 2.1e-95 319.3 18.4 2.7e-95 318.9 18.4 1.1 1 0 0 1 1 1 1 Fungal potassium channel LRR_4 PF12799.7 CCD23153.1 - 0.22 12.0 27.6 0.093 13.2 1.4 5.8 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CCD23153.1 - 0.4 10.9 12.9 3 8.1 0.0 6.5 6 0 0 6 6 6 0 Leucine Rich repeat IBB PF01749.20 CCD23153.1 - 3.8 8.0 10.4 0.083 13.3 2.4 2.3 2 1 0 2 2 2 0 Importin beta binding domain FAD_binding_2 PF00890.24 CCD23154.1 - 1.5e-68 231.8 0.0 1.9e-68 231.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CCD23154.1 - 1.4e-08 34.7 0.1 1.2e-06 28.4 0.0 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCD23154.1 - 4.5e-06 26.8 0.0 1.3e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CCD23154.1 - 5.6e-06 25.8 2.2 0.00017 20.9 1.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCD23154.1 - 1.8e-05 24.1 1.3 0.0016 17.7 0.1 2.4 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.6 CCD23154.1 - 0.017 15.2 0.0 0.08 12.9 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CCD23154.1 - 0.041 13.1 0.6 4 6.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CCD23154.1 - 0.096 11.4 6.0 0.06 12.0 1.8 2.5 2 1 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 CCD23154.1 - 0.11 11.7 0.2 0.19 10.9 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain DUF3659 PF12396.8 CCD23154.1 - 0.12 12.3 0.3 0.94 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Beta_elim_lyase PF01212.21 CCD23155.1 - 2e-79 267.0 0.0 2.4e-79 266.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Isy1 PF06246.12 CCD23156.1 - 1.3e-53 182.2 19.4 1.5e-53 182.0 19.4 1.1 1 0 0 1 1 1 1 Isy1-like splicing family NAD_kinase PF01513.21 CCD23157.1 - 1e-89 300.6 0.0 1.7e-89 299.9 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 CCD23157.1 - 0.052 13.2 0.0 0.44 10.2 0.0 2.1 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Mid2 PF04478.12 CCD23157.1 - 1.9 8.3 5.3 0.23 11.3 0.9 1.7 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Cytochrom_C PF00034.21 CCD23158.1 - 3.7e-11 44.0 0.1 7.8e-11 43.0 0.1 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CCD23158.1 - 2e-06 28.0 1.0 9.8e-06 25.8 1.0 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CCD23158.1 - 0.078 12.7 2.1 0.75 9.5 2.0 2.1 1 1 0 1 1 1 0 Cytochrome c-550 domain Anp1 PF03452.14 CCD23159.1 - 1.6e-109 365.4 0.0 2.6e-109 364.7 0.0 1.3 1 0 0 1 1 1 1 Anp1 eIF-5a PF01287.20 CCD23160.1 - 3e-29 100.9 0.5 4.1e-29 100.5 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CCD23160.1 - 0.0019 18.2 0.1 0.0029 17.6 0.1 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain TgMIC1 PF11476.8 CCD23160.1 - 0.023 14.5 0.1 0.084 12.6 0.0 1.8 1 1 1 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 PWWP PF00855.17 CCD23161.1 - 3.6e-24 85.0 0.3 3.6e-24 85.0 0.3 2.8 2 1 1 3 3 3 1 PWWP domain Ndc1_Nup PF09531.10 CCD23161.1 - 0.55 8.9 2.2 0.59 8.8 2.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRF-TF PF00319.18 CCD23162.1 - 4.2e-21 74.2 0.2 6.6e-21 73.5 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Spt5_N PF11942.8 CCD23162.1 - 0.097 13.7 14.0 0.19 12.7 5.4 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CAC1F_C PF16885.5 CCD23162.1 - 0.29 10.8 15.3 0.44 10.2 15.3 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term CPSF100_C PF13299.6 CCD23162.1 - 0.45 10.7 8.7 6.1 7.0 3.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SRF-TF PF00319.18 CCD23163.1 - 3.7e-21 74.3 0.1 6.1e-21 73.6 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AJAP1_PANP_C PF15298.6 CCD23163.1 - 0.19 11.9 3.3 0.47 10.6 0.5 2.0 2 0 0 2 2 2 0 AJAP1/PANP C-terminus DNA_pol_phi PF04931.13 CCD23163.1 - 0.36 8.9 15.6 0.51 8.4 15.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF5523 PF17661.1 CCD23163.1 - 0.4 10.3 11.3 0.57 9.8 11.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Nop14 PF04147.12 CCD23163.1 - 1.2 7.3 18.9 1.5 6.9 18.9 1.0 1 0 0 1 1 1 0 Nop14-like family SLAIN PF15301.6 CCD23163.1 - 4.6 6.4 12.6 4.2 6.5 0.7 2.1 1 1 1 2 2 2 0 SLAIN motif-containing family CDC45 PF02724.14 CCD23163.1 - 6 5.0 7.8 7.1 4.8 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 CCD23163.1 - 6.4 6.0 19.8 8.4 5.6 19.8 1.1 1 0 0 1 1 1 0 BUD22 Aldo_ket_red PF00248.21 CCD23164.1 - 9.3e-46 156.3 0.0 1.1e-45 156.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Bap31 PF05529.12 CCD23165.1 - 3.5e-22 78.7 7.1 4.5e-22 78.4 7.1 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region MBT PF02820.18 CCD23165.1 - 0.13 12.6 0.1 0.55 10.6 0.0 1.9 2 0 0 2 2 2 0 mbt repeat PC4 PF02229.16 CCD23166.1 - 4.3e-22 77.5 0.1 9.6e-22 76.4 0.1 1.6 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DUF4551 PF15087.6 CCD23166.1 - 2 7.1 9.0 2.3 6.9 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) HMA PF00403.26 CCD23167.1 - 1.3e-07 32.0 0.1 2.8e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 CCD23167.1 - 0.0017 18.5 0.0 0.0077 16.4 0.0 1.9 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) zf-C2H2 PF00096.26 CCD23168.1 - 5.7e-11 42.2 12.5 1.7e-05 25.0 4.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD23168.1 - 4.2e-09 36.5 12.4 0.00042 20.9 3.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCD23168.1 - 1.4e-06 28.4 18.9 1.3e-05 25.4 3.3 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CCD23168.1 - 0.00099 19.3 12.0 0.0085 16.4 4.0 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CCD23168.1 - 0.0066 16.7 4.5 0.013 15.8 4.5 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CCD23168.1 - 0.011 16.1 8.2 0.034 14.6 2.0 3.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.15 CCD23168.1 - 0.018 15.1 11.4 0.023 14.7 0.8 3.0 3 0 0 3 3 2 0 BED zinc finger zf-C2HE PF16278.5 CCD23168.1 - 0.038 14.4 11.1 0.65 10.5 0.9 3.0 2 1 1 3 3 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 CCD23168.1 - 0.068 13.5 1.4 0.2 12.0 1.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CCD23168.1 - 0.16 12.0 17.1 0.093 12.8 4.3 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger GAGA PF09237.11 CCD23168.1 - 0.54 10.1 2.9 6.9 6.6 0.9 2.5 1 1 1 2 2 2 0 GAGA factor zf-H2C2_5 PF13909.6 CCD23168.1 - 0.88 9.4 14.8 1.7 8.5 0.6 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 CCD23168.1 - 2.1 8.2 6.6 4.6 7.1 1.0 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CCD23168.1 - 3.6 8.0 8.6 9.1 6.7 1.9 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Rhodanese PF00581.20 CCD23169.1 - 6.8e-13 49.1 0.0 1.8e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_S26 PF10502.9 CCD23170.1 - 0.00014 21.6 0.0 0.0046 16.7 0.0 2.1 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 CCD23170.1 - 0.00066 19.6 0.1 0.0019 18.1 0.1 1.8 1 1 0 1 1 1 1 Peptidase S24-like SBF_like PF13593.6 CCD23171.1 - 6e-120 400.3 12.1 7e-120 400.1 12.1 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 CCD23171.1 - 1.9e-12 47.3 6.8 3.3e-12 46.5 6.8 1.3 1 0 0 1 1 1 1 Sodium Bile acid symporter family FCH PF00611.23 CCD23172.1 - 1.7e-11 44.2 2.5 3.3e-11 43.3 0.1 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 CCD23172.1 - 0.044 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 SH3 domain Eisosome1 PF12757.7 CCD23173.1 - 2.3e-28 98.9 0.5 2.3e-28 98.9 0.5 5.1 5 1 1 6 6 6 1 Eisosome protein 1 Frag1 PF10277.9 CCD23174.1 - 4.4e-79 265.1 23.5 5.2e-79 264.8 23.5 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4079 PF13301.6 CCD23174.1 - 0.0062 16.7 1.6 0.017 15.3 1.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF4079) CobS PF02654.15 CCD23174.1 - 0.45 10.7 7.1 0.64 10.2 2.5 2.2 2 0 0 2 2 2 0 Cobalamin-5-phosphate synthase DUF2627 PF11118.8 CCD23174.1 - 6 7.5 6.4 0.63 10.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) CUE PF02845.16 CCD23175.1 - 8.9e-05 22.1 0.1 8.9e-05 22.1 0.1 1.7 2 0 0 2 2 2 1 CUE domain Striatin PF08232.12 CCD23176.1 - 2.3e-19 70.5 13.8 3.2e-19 70.1 0.7 3.1 2 1 1 3 3 3 2 Striatin family ANAPC4_WD40 PF12894.7 CCD23176.1 - 0.008 16.5 0.2 1.4 9.2 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ax_dynein_light PF10211.9 CCD23176.1 - 0.027 14.4 8.4 0.039 13.9 7.3 1.8 1 1 0 1 1 1 0 Axonemal dynein light chain Mto2_bdg PF12808.7 CCD23176.1 - 0.074 13.4 2.7 0.23 11.8 2.7 1.9 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PKI PF02827.16 CCD23176.1 - 0.25 11.6 2.9 0.83 9.9 2.9 1.9 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor TAP42 PF04177.12 CCD23178.1 - 1.8e-84 283.6 19.0 2.1e-84 283.4 19.0 1.0 1 0 0 1 1 1 1 TAP42-like family DUF89 PF01937.19 CCD23179.1 - 2.5e-111 372.1 5.3 2.8e-111 371.9 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Pex2_Pex12 PF04757.14 CCD23180.1 - 1.3e-45 155.7 9.5 1.8e-45 155.3 9.5 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CCD23180.1 - 1.1e-06 28.3 8.0 1.7e-06 27.8 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCD23180.1 - 2.6e-05 24.0 4.8 4.5e-05 23.2 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCD23180.1 - 0.0051 16.9 8.3 0.0093 16.1 8.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CCD23180.1 - 0.0072 16.6 5.0 0.013 15.8 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CCD23180.1 - 0.0083 16.0 6.7 0.015 15.2 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCD23180.1 - 0.044 13.8 7.3 0.086 12.9 7.3 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CCD23180.1 - 1.2 9.1 6.0 2.2 8.3 6.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 CCD23180.1 - 1.4 8.8 6.1 4.4 7.2 1.5 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 CCD23180.1 - 4 7.4 5.6 23 5.0 0.1 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif MitMem_reg PF13012.6 CCD23181.1 - 0.0076 16.7 2.2 0.015 15.7 0.4 2.1 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function SDP_N PF12278.8 CCD23181.1 - 0.008 16.3 4.6 0.02 15.0 4.6 1.7 1 0 0 1 1 1 1 Sex determination protein N terminal dsrm PF00035.26 CCD23182.1 - 9e-09 35.9 0.0 1.9e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 CCD23182.1 - 0.00018 22.1 0.1 0.00051 20.6 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease III domain RNaseH_C PF09293.10 CCD23182.1 - 0.19 12.1 0.9 7.5 6.9 0.0 2.8 3 0 0 3 3 3 0 T4 RNase H, C terminal Helicase_C PF00271.31 CCD23183.1 - 4.5e-12 46.3 0.0 1e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCD23183.1 - 2.9e-08 33.7 0.0 6.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase mTERF PF02536.14 CCD23183.1 - 0.02 13.8 0.8 0.034 13.1 0.8 1.2 1 0 0 1 1 1 0 mTERF ResIII PF04851.15 CCD23183.1 - 0.024 14.7 0.0 0.099 12.6 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF5033 PF16436.5 CCD23183.1 - 0.053 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5033) DUF1492 PF07374.11 CCD23183.1 - 0.25 11.5 0.9 1 9.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) MnmE_helical PF12631.7 CCD23184.1 - 4.4e-43 147.9 4.0 1.2e-42 146.4 4.0 1.7 1 1 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 CCD23184.1 - 3.2e-36 124.2 0.0 7.2e-36 123.0 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 CCD23184.1 - 1.3e-23 83.2 0.9 1.3e-23 83.2 0.9 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCD23184.1 - 7.1e-12 45.1 1.9 1.3e-11 44.2 1.9 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CCD23184.1 - 8.4e-10 38.8 6.8 2.3e-05 24.4 0.5 2.9 2 1 1 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 CCD23184.1 - 1.3e-08 34.7 1.7 2e-06 27.5 0.3 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 CCD23184.1 - 1.5e-05 24.5 1.9 0.00026 20.5 1.9 2.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CCD23184.1 - 1.6e-05 24.6 0.3 3.6e-05 23.4 0.3 1.7 1 0 0 1 1 1 1 Ras family MeaB PF03308.16 CCD23184.1 - 0.00098 18.2 1.6 0.99 8.3 0.1 3.5 2 1 1 4 4 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CCD23184.1 - 0.0018 18.4 3.8 0.0032 17.5 1.2 2.8 3 1 0 3 3 3 1 Dynamin family AIG1 PF04548.16 CCD23184.1 - 0.002 17.5 1.7 0.0043 16.4 1.7 1.6 1 0 0 1 1 1 1 AIG1 family PduV-EutP PF10662.9 CCD23184.1 - 0.011 15.5 3.2 0.95 9.2 0.4 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Phage_CII PF05269.11 CCD23184.1 - 0.011 15.9 0.0 0.72 10.1 0.0 3.2 2 0 0 2 2 2 0 Bacteriophage CII protein Roc PF08477.13 CCD23184.1 - 0.014 15.7 0.2 0.09 13.0 0.2 2.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CCD23184.1 - 0.018 14.7 4.9 0.026 14.1 2.8 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 CCD23184.1 - 0.059 13.0 1.1 0.11 12.1 0.3 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CCD23184.1 - 0.068 13.6 0.0 0.56 10.6 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 CCD23184.1 - 0.22 12.0 6.3 0.1 13.1 3.1 2.2 1 1 1 2 2 2 0 ABC transporter Beta_protein PF14350.6 CCD23184.1 - 0.53 9.6 2.9 0.58 9.5 0.4 2.0 2 0 0 2 2 2 0 Beta protein Glyco_hydro_76 PF03663.14 CCD23185.1 - 5.8e-158 526.2 26.3 6.7e-158 526.0 26.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 UQ_con PF00179.26 CCD23186.1 - 8.8e-50 168.0 0.0 1e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCD23186.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 CCD23186.1 - 0.19 12.0 0.6 0.28 11.5 0.5 1.7 1 1 0 1 1 1 0 RWD domain Amino_oxidase PF01593.24 CCD23187.1 - 1.2e-63 216.1 0.0 1.6e-63 215.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CCD23187.1 - 9.5e-10 38.6 0.2 2.1e-09 37.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CCD23187.1 - 1e-06 28.2 0.0 0.00041 19.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CCD23187.1 - 3.1e-05 23.2 2.2 0.00065 18.9 0.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 CCD23187.1 - 3.2e-05 23.7 0.5 0.0007 19.3 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CCD23187.1 - 3.4e-05 23.1 0.6 5.6e-05 22.4 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CCD23187.1 - 6.1e-05 22.6 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CCD23187.1 - 0.0003 19.6 1.3 0.0082 14.9 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 CCD23187.1 - 0.00039 19.8 0.1 0.0007 18.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 CCD23187.1 - 0.0004 19.7 4.1 0.0027 17.0 0.5 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CCD23187.1 - 0.0066 16.5 0.4 0.032 14.3 0.1 2.3 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 CCD23187.1 - 0.033 13.4 0.2 0.058 12.6 0.2 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 CCD23187.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 CCD23187.1 - 0.086 11.9 0.5 0.14 11.2 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Tricorn_C1 PF14684.6 CCD23187.1 - 0.1 12.7 0.1 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 Tricorn protease C1 domain Pyr_redox PF00070.27 CCD23187.1 - 0.1 13.2 2.9 0.41 11.2 0.2 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PepSY_like PF11396.8 CCD23187.1 - 0.12 12.9 2.1 0.23 12.1 0.1 2.4 3 0 0 3 3 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like Fungal_trans PF04082.18 CCD23188.1 - 9.1e-20 70.8 11.6 9.1e-20 70.8 11.6 2.6 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD23188.1 - 1.1e-10 41.5 13.4 2.3e-10 40.4 13.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 CCD23190.1 - 6.4e-52 176.8 0.1 8.5e-52 176.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 BUD22 PF09073.10 CCD23191.1 - 1.8e-81 274.7 48.0 2.3e-81 274.4 48.0 1.1 1 0 0 1 1 1 1 BUD22 CLU PF13236.6 CCD23193.1 - 5e-60 203.1 0.3 1.4e-59 201.6 0.3 1.8 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 CCD23193.1 - 1.1e-35 123.3 7.1 1.1e-35 123.2 0.0 3.6 4 1 0 4 4 4 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 CCD23193.1 - 2.9e-19 69.2 1.9 1e-18 67.5 0.5 2.9 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term DUF727 PF05303.12 CCD23193.1 - 5.8e-07 29.5 0.3 2.5e-06 27.5 0.3 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_12 PF13424.6 CCD23193.1 - 0.00043 20.5 0.3 0.042 14.2 0.0 3.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 CCD23193.1 - 0.0059 16.4 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Cas_APE2256 PF09651.10 CCD23193.1 - 0.025 14.4 1.3 4.2 7.3 0.2 2.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) TPR_8 PF13181.6 CCD23193.1 - 0.039 14.2 0.3 0.17 12.1 0.3 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat PEX11 PF05648.14 CCD23193.1 - 1.7 8.1 5.4 0.21 11.1 0.4 2.0 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Fib_alpha PF08702.10 CCD23193.1 - 7.4 6.7 12.4 68 3.6 0.0 4.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Opi1 PF08618.10 CCD23194.1 - 4.2e-29 102.1 8.8 6.9e-20 71.7 5.9 3.4 1 1 1 2 2 2 2 Transcription factor Opi1 CENP-B_dimeris PF09026.10 CCD23194.1 - 0.00058 20.2 27.2 0.011 16.2 1.7 3.4 3 0 0 3 3 3 2 Centromere protein B dimerisation domain Prothymosin PF03247.14 CCD23194.1 - 0.26 11.8 39.7 1 9.8 4.8 3.6 3 0 0 3 3 3 0 Prothymosin/parathymosin family NOA36 PF06524.12 CCD23194.1 - 2.2 7.6 36.8 2 7.7 5.3 3.3 3 0 0 3 3 3 0 NOA36 protein DUF775 PF05603.12 CCD23194.1 - 5.5 6.5 10.8 1.5 8.3 4.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF775) Adap_comp_sub PF00928.21 CCD23195.1 - 1.2e-68 231.3 3.1 1.6e-67 227.7 3.1 2.2 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Presenilin PF01080.17 CCD23195.1 - 6.4 5.4 6.9 29 3.2 0.0 3.0 3 0 0 3 3 3 0 Presenilin YL1 PF05764.13 CCD23195.1 - 8 6.5 23.4 3.5 7.7 1.5 3.2 3 0 0 3 3 3 0 YL1 nuclear protein Pterin_4a PF01329.19 CCD23196.1 - 5.5e-22 77.8 0.0 6.9e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase NifU PF01106.17 CCD23197.1 - 2.5e-25 88.4 0.0 4.6e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 CCD23197.1 - 2.7e-19 69.0 0.1 9.8e-19 67.2 0.0 2.0 2 1 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal YojJ PF10372.9 CCD23197.1 - 0.0051 16.9 0.2 0.011 15.9 0.2 1.5 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus SSF PF00474.17 CCD23198.1 - 4.7e-18 65.2 31.1 9.8e-18 64.2 31.1 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2207 PF09972.9 CCD23198.1 - 0.00018 20.4 0.3 0.00018 20.4 0.3 4.6 1 1 1 3 3 3 1 Predicted membrane protein (DUF2207) COG6 PF06419.11 CCD23198.1 - 0.21 9.8 1.2 0.3 9.3 1.2 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 RP-C_C PF11800.8 CCD23198.1 - 0.26 11.3 0.3 0.49 10.5 0.3 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Ribosomal_S10 PF00338.22 CCD23199.1 - 2.8e-24 85.2 1.6 5.7e-24 84.2 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e GerD PF17898.1 CCD23199.1 - 0.019 14.9 0.4 0.026 14.5 0.4 1.3 1 0 0 1 1 1 0 Spore germination GerD central core domain YchF-GTPase_C PF06071.13 CCD23200.1 - 2.1e-28 98.3 0.2 8.3e-28 96.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CCD23200.1 - 5e-17 62.0 0.2 2.5e-16 59.8 0.0 2.1 1 1 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 CCD23200.1 - 6.6e-05 22.9 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CCD23200.1 - 0.00078 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B 2-Hacid_dh_C PF02826.19 CCD23200.1 - 0.027 13.9 0.0 10 5.5 0.0 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OTU PF02338.19 CCD23201.1 - 1.5e-27 96.6 0.1 1.5e-27 96.6 0.1 2.0 3 0 0 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CCD23201.1 - 0.00029 20.4 4.5 0.00074 19.0 0.0 2.8 2 1 1 3 3 3 1 Peptidase C65 Otubain Cep57_MT_bd PF06657.13 CCD23201.1 - 0.029 14.8 5.6 0.029 14.8 5.6 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 cwf21 PF08312.12 CCD23201.1 - 7.4 6.8 12.7 4.3 7.6 5.9 2.8 2 1 0 2 2 2 0 cwf21 domain Zn_clus PF00172.18 CCD23202.1 - 4.3e-07 29.9 8.6 9e-07 28.9 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UDPGP PF01704.18 CCD23203.1 - 1.4e-185 616.9 0.0 2e-185 616.3 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase MIS13 PF08202.11 CCD23204.1 - 1.5e-55 188.6 51.8 1.5e-55 188.6 51.8 3.9 2 2 0 2 2 2 1 Mis12-Mtw1 protein family ANAPC4_WD40 PF12894.7 CCD23205.1 - 7.2e-08 32.6 0.5 0.0012 19.1 0.0 4.5 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCD23205.1 - 0.0018 19.1 7.0 3.2 8.8 0.8 5.5 7 0 0 7 7 7 2 WD domain, G-beta repeat PQQ PF01011.21 CCD23205.1 - 0.19 11.7 0.3 1.9 8.5 0.0 2.8 3 0 0 3 3 3 0 PQQ enzyme repeat Asp PF00026.23 CCD23206.1 - 3.8e-71 240.1 0.6 5.7e-71 239.5 0.6 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCD23206.1 - 2.5e-07 31.1 2.4 3.1e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Pox_vIL-18BP PF05566.12 CCD23206.1 - 0.0041 17.3 0.0 0.0099 16.1 0.0 1.6 1 0 0 1 1 1 1 Orthopoxvirus interleukin 18 binding protein BAG PF02179.16 CCD23207.1 - 3.1e-15 56.4 3.7 5e-15 55.7 3.7 1.3 1 0 0 1 1 1 1 BAG domain SAS4 PF15460.6 CCD23207.1 - 0.016 15.3 2.9 0.044 13.9 2.9 1.9 1 1 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 DUF5549 PF17703.1 CCD23207.1 - 0.97 9.1 2.2 1.3 8.6 2.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5549) U-box PF04564.15 CCD23208.1 - 0.0021 18.2 0.2 1.6 9.0 0.0 3.0 2 0 0 2 2 2 2 U-box domain HEAT PF02985.22 CCD23208.1 - 0.0077 16.4 0.0 0.058 13.7 0.0 2.7 1 0 0 1 1 1 1 HEAT repeat DUF5071 PF16804.5 CCD23208.1 - 0.027 14.7 1.6 0.75 10.1 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5071) YrzO PF14142.6 CCD23208.1 - 0.13 12.1 1.0 0.46 10.4 1.0 1.9 1 0 0 1 1 1 0 YrzO-like protein FAM76 PF16046.5 CCD23208.1 - 0.48 9.7 2.8 1.3 8.3 2.8 1.7 1 0 0 1 1 1 0 FAM76 protein DUF5085 PF16895.5 CCD23208.1 - 0.73 10.2 10.0 1.4 9.2 2.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5085) Ribosomal_L2_C PF03947.18 CCD23209.1 - 1.3e-44 151.4 3.5 2.2e-44 150.7 3.5 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CCD23209.1 - 2.1e-13 50.0 0.2 5.7e-13 48.6 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L29e PF01779.17 CCD23210.1 - 8.6e-23 80.4 10.1 1.2e-22 79.9 10.1 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family His_biosynth PF00977.21 CCD23211.1 - 5.2e-27 94.8 0.0 6.9e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein Tim44 PF04280.15 CCD23212.1 - 2.6e-37 128.2 0.0 6.7e-37 126.8 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain DUF2207 PF09972.9 CCD23213.1 - 0.012 14.4 0.2 0.012 14.4 0.2 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) bZIP_1 PF00170.21 CCD23214.1 - 3.2e-05 23.9 17.0 8.9e-05 22.5 17.0 1.8 1 0 0 1 1 1 1 bZIP transcription factor DUF349 PF03993.12 CCD23214.1 - 0.94 9.8 11.7 1.9 8.9 10.0 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) IATP PF04568.12 CCD23214.1 - 1.2 9.6 7.1 3.3 8.2 7.1 1.8 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF4407 PF14362.6 CCD23214.1 - 4.3 6.6 7.7 6.4 6.0 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Auxin_canalis PF05703.11 CCD23214.1 - 6 6.7 10.9 0.69 9.8 1.6 2.4 2 0 0 2 2 2 0 Auxin canalisation Form_Nir_trans PF01226.17 CCD23215.1 - 2.4e-61 207.1 18.6 3.1e-61 206.7 18.6 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter BRAP2 PF07576.12 CCD23216.1 - 3.9e-31 107.2 0.4 1.3e-30 105.5 0.4 1.8 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 CCD23216.1 - 6.8e-21 74.4 7.5 1.6e-20 73.1 7.5 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 CCD23216.1 - 1.8e-09 37.8 11.0 1.8e-09 37.8 11.0 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CCD23216.1 - 1.3e-06 28.1 10.4 3.2e-06 26.9 10.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CCD23216.1 - 6.3e-06 25.8 5.3 1.9e-05 24.3 5.3 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CCD23216.1 - 1.2e-05 25.2 4.6 1.2e-05 25.2 4.6 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CCD23216.1 - 2.8e-05 23.9 9.8 2.8e-05 23.9 9.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CCD23216.1 - 4.7e-05 23.6 7.3 0.00015 22.0 7.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CCD23216.1 - 0.00011 22.0 8.3 0.00011 22.0 8.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CCD23216.1 - 0.00013 21.8 6.6 0.00013 21.8 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CCD23216.1 - 0.0022 18.0 2.8 0.0087 16.1 2.8 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CCD23216.1 - 0.014 15.3 11.8 0.014 15.3 11.8 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-UBP_var PF17807.1 CCD23216.1 - 0.041 13.6 0.9 0.13 12.1 0.9 1.8 1 0 0 1 1 1 0 Variant UBP zinc finger Flp_N PF03930.14 CCD23216.1 - 1 9.4 6.4 7.5 6.6 0.6 3.0 2 1 1 3 3 3 0 Recombinase Flp protein N-terminus zf-RING_4 PF14570.6 CCD23216.1 - 1.2 9.0 14.3 0.06 13.2 8.1 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain LMBR1 PF04791.16 CCD23216.1 - 2.4 7.0 8.7 4.1 6.2 8.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Methyltr_RsmB-F PF01189.17 CCD23217.1 - 3.1e-42 144.5 0.0 1e-41 142.8 0.0 1.9 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CCD23217.1 - 0.00049 20.2 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-UBR PF02207.20 CCD23218.1 - 2.4e-08 34.0 17.6 2.4e-08 34.0 17.6 2.8 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) GT-D PF08759.11 CCD23218.1 - 0.037 13.7 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold ArfGap PF01412.18 CCD23219.1 - 1.7e-25 89.4 2.4 3.3e-25 88.4 2.4 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.31 CCD23219.1 - 0.00075 19.4 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Sep15_SelM PF08806.11 CCD23219.1 - 0.14 12.4 0.1 0.9 9.7 0.0 2.2 1 1 1 2 2 2 0 Sep15/SelM redox domain Acid_PPase PF12689.7 CCD23220.1 - 1.9e-44 151.5 0.0 2.2e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase GST_C_2 PF13410.6 CCD23221.1 - 1.8e-06 27.8 0.0 4.5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CCD23221.1 - 0.0008 19.7 0.1 0.0047 17.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain EMP24_GP25L PF01105.24 CCD23223.1 - 5.4e-43 147.0 0.2 8e-43 146.5 0.2 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD POC3_POC4 PF10448.9 CCD23223.1 - 0.025 14.6 0.1 0.031 14.3 0.1 1.2 1 0 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 Metallophos PF00149.28 CCD23224.1 - 2.7e-40 139.0 0.1 3.6e-40 138.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CCD23224.1 - 1.1e-22 80.2 1.5 1.8e-22 79.5 0.5 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Kelch_6 PF13964.6 CCD23225.1 - 4.3e-14 52.2 0.6 1.8e-05 24.9 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 CCD23225.1 - 8e-11 41.4 3.4 1.5e-05 24.4 0.0 5.4 5 1 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 CCD23225.1 - 2e-10 40.7 0.3 0.054 13.8 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 CCD23225.1 - 2.7e-10 40.1 3.7 0.0071 16.3 0.0 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CCD23225.1 - 1.3e-08 34.5 0.0 0.0081 16.1 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CCD23225.1 - 0.00013 21.8 0.0 0.37 10.8 0.0 3.2 2 0 0 2 2 2 2 Kelch motif WD40 PF00400.32 CCD23226.1 - 7.3e-17 61.4 0.9 0.0014 19.4 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat SGL PF08450.12 CCD23226.1 - 0.035 13.7 0.0 0.14 11.7 0.0 1.9 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region BRCT PF00533.26 CCD23226.1 - 0.044 14.2 3.4 1.6 9.2 0.3 2.9 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Ribosomal_S26e PF01283.19 CCD23227.1 - 9.6e-52 174.0 11.1 1.1e-51 173.8 11.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_2 PF12797.7 CCD23227.1 - 0.1 12.7 1.0 0.1 12.7 1.0 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain zf-C2H2 PF00096.26 CCD23228.1 - 1.4e-09 37.9 22.0 5.1e-06 26.6 3.4 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD23228.1 - 1.4e-07 31.8 19.4 0.00014 22.4 1.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCD23228.1 - 5.1e-07 29.8 11.6 0.003 17.8 1.1 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CCD23228.1 - 1.4e-05 25.3 2.7 1.4e-05 25.3 2.7 4.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 CCD23228.1 - 0.00089 19.6 7.8 0.31 11.5 3.0 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-BED PF02892.15 CCD23228.1 - 0.00095 19.1 6.5 0.34 11.0 1.4 2.8 2 0 0 2 2 2 2 BED zinc finger zf-Di19 PF05605.12 CCD23228.1 - 0.0016 18.6 2.8 0.0016 18.6 2.8 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 CCD23228.1 - 0.039 14.4 5.0 4.4 7.8 0.6 3.1 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger PyrI_C PF02748.15 CCD23228.1 - 0.082 12.8 3.4 0.36 10.8 0.1 2.9 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.6 CCD23228.1 - 0.58 10.2 11.0 0.78 9.8 2.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CCD23228.1 - 5.1 7.5 13.7 1.6 9.1 0.5 3.2 3 1 1 4 4 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CCD23229.1 - 6.8e-06 26.2 11.4 0.00075 19.8 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 CCD23229.1 - 0.013 15.9 0.6 0.013 15.9 0.6 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CCD23229.1 - 0.051 14.4 1.1 0.051 14.4 1.1 3.3 3 1 1 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCD23229.1 - 0.06 13.8 0.3 0.06 13.8 0.3 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.15 CCD23229.1 - 0.28 11.2 5.8 0.32 11.1 2.6 2.5 1 1 0 2 2 2 0 BED zinc finger eIF-6 PF01912.18 CCD23230.1 - 4.1e-82 274.4 0.3 5.2e-82 274.0 0.3 1.1 1 0 0 1 1 1 1 eIF-6 family Actin PF00022.19 CCD23231.1 - 5.9e-54 183.2 0.0 1.1e-52 179.0 0.0 2.4 1 1 0 1 1 1 1 Actin SMC_N PF02463.19 CCD23232.1 - 2.6e-69 233.0 43.8 8.9e-69 231.3 43.8 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CCD23232.1 - 4e-21 75.5 0.3 1.7e-20 73.5 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CCD23232.1 - 2e-10 41.0 1.5 1.2e-05 25.3 1.1 4.6 3 1 2 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCD23232.1 - 0.00011 21.9 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CCD23232.1 - 0.00044 20.1 38.6 0.00044 20.1 38.6 4.5 2 2 2 4 4 4 1 AAA ATPase domain ERM PF00769.19 CCD23232.1 - 0.0017 18.2 17.1 0.0017 18.2 17.1 5.7 2 2 1 4 4 4 3 Ezrin/radixin/moesin family Occludin_ELL PF07303.13 CCD23232.1 - 0.0024 18.5 3.6 0.0024 18.5 3.6 9.1 3 2 6 9 9 9 1 Occludin homology domain YabA PF06156.13 CCD23232.1 - 0.0046 17.6 3.4 0.0046 17.6 3.4 8.7 4 3 6 10 10 10 2 Initiation control protein YabA SbcCD_C PF13558.6 CCD23232.1 - 0.033 14.4 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 CCD23232.1 - 1.8 9.1 0.0 1.8 9.1 0.0 6.6 4 3 0 5 5 5 0 ABC transporter Aminotran_1_2 PF00155.21 CCD23234.1 - 2.1e-30 106.2 0.0 2.9e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Ig_GlcNase PF18368.1 CCD23234.1 - 0.53 10.5 2.9 3.4 7.9 1.0 2.3 2 0 0 2 2 2 0 Exo-beta-D-glucosaminidase Ig-fold domain DnaJ_C PF01556.18 CCD23235.1 - 1e-31 110.0 0.3 1.6e-31 109.4 0.3 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCD23235.1 - 1.7e-27 95.3 3.1 4.7e-26 90.7 2.0 2.4 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CCD23235.1 - 1e-10 41.8 10.8 3.5e-10 40.1 11.0 1.8 1 1 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.6 CCD23235.1 - 6.4e-05 23.3 0.8 6.4e-05 23.3 0.8 2.4 2 1 0 2 2 2 1 Cytochrome c3 Anti-TRAP PF15777.5 CCD23235.1 - 0.01 15.7 8.4 0.065 13.2 0.7 3.1 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrome_C554 PF13435.6 CCD23235.1 - 0.017 16.0 4.2 0.43 11.5 0.5 3.3 2 1 1 3 3 3 0 Cytochrome c554 and c-prime zinc_ribbon_6 PF14599.6 CCD23235.1 - 0.032 14.2 0.7 0.032 14.2 0.7 2.6 2 1 0 2 2 2 0 Zinc-ribbon Biotin_lipoyl_2 PF13533.6 CCD23235.1 - 0.099 12.5 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Biotin-lipoyl like Cytochrome_C7 PF14522.6 CCD23235.1 - 1.9 8.6 12.7 13 5.8 12.8 2.3 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c NinE PF05322.11 CCD23235.1 - 2.6 8.0 4.6 0.44 10.5 0.2 1.9 2 0 0 2 2 2 0 NINE Protein Zn-ribbon_8 PF09723.10 CCD23235.1 - 3.2 8.0 8.4 1.9 8.7 2.4 2.9 3 0 0 3 3 3 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 CCD23235.1 - 4.6 7.1 12.7 1.4 8.8 1.2 3.5 2 1 1 3 3 3 0 A2L zinc ribbon domain Cytochrome_CBB3 PF13442.6 CCD23235.1 - 4.9 7.5 7.4 14 6.1 0.6 2.9 2 1 1 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III GEP5 PF17053.5 CCD23236.1 - 3.5e-69 233.1 11.5 4.4e-69 232.7 11.5 1.1 1 0 0 1 1 1 1 Genetic interactor of prohibitin 5 Nsp1_C PF05064.13 CCD23236.1 - 0.029 14.2 1.1 0.068 13.0 0.3 2.1 2 1 0 2 2 2 0 Nsp1-like C-terminal region HDC PF02329.16 CCD23236.1 - 0.048 12.7 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 Histidine carboxylase PI chain Bunya_NS-S PF01104.17 CCD23236.1 - 0.12 12.2 2.6 0.54 10.1 0.7 2.3 2 0 0 2 2 2 0 Bunyavirus non-structural protein NS-s Sulfate_transp PF00916.20 CCD23237.1 - 2.4e-125 418.2 10.0 3.2e-125 417.9 10.0 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CCD23237.1 - 3.9e-06 26.5 0.0 7.5e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CCD23237.1 - 0.007 16.7 0.1 0.015 15.7 0.1 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CCD23237.1 - 0.026 14.9 1.0 0.026 14.9 1.0 2.2 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Nyv1_N PF09426.10 CCD23239.1 - 3.4e-61 205.3 0.4 3.4e-61 205.3 0.4 1.5 2 0 0 2 2 2 1 Vacuolar R-SNARE Nyv1 N terminal Synaptobrevin PF00957.21 CCD23239.1 - 2.8e-26 91.1 3.0 4e-26 90.6 3.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Fzo_mitofusin PF04799.13 CCD23239.1 - 0.017 14.7 0.3 0.026 14.1 0.3 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF1002 PF06207.11 CCD23239.1 - 0.055 13.0 2.3 0.075 12.6 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) DUF2391 PF09622.10 CCD23239.1 - 0.076 12.3 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) Ribosomal_S10 PF00338.22 CCD23240.1 - 0.059 13.6 0.5 0.98 9.7 0.1 3.0 3 0 0 3 3 3 0 Ribosomal protein S10p/S20e PHD PF00628.29 CCD23241.1 - 0.02 14.8 1.5 0.062 13.2 1.5 1.8 1 0 0 1 1 1 0 PHD-finger Prion PF00377.18 CCD23241.1 - 0.078 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain Pkinase PF00069.25 CCD23242.1 - 1.6e-69 234.2 1.7 3.4e-67 226.6 1.7 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23242.1 - 7.6e-41 140.1 0.5 5.1e-39 134.1 0.5 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CCD23242.1 - 4.8e-18 64.7 0.1 9.6e-18 63.7 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 CCD23242.1 - 9.9e-07 28.3 0.0 2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CCD23242.1 - 0.00034 20.0 0.2 0.00069 19.0 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CCD23242.1 - 0.0024 16.7 2.2 0.0046 15.8 0.3 2.6 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CCD23242.1 - 0.0081 16.1 0.1 0.25 11.3 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CCD23242.1 - 0.0083 15.1 3.5 0.016 14.2 0.2 2.5 2 0 0 2 2 2 1 Haspin like kinase domain zf-C2H2 PF00096.26 CCD23243.1 - 1e-08 35.2 11.5 0.00037 20.8 2.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD23243.1 - 7.8e-06 26.3 11.0 0.024 15.4 1.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCD23243.1 - 0.00014 22.1 12.7 0.00016 22.0 0.9 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 CCD23243.1 - 0.011 16.1 8.3 0.023 15.1 1.0 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCD23243.1 - 0.42 11.0 5.8 1.7 9.0 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CCD23243.1 - 1 10.1 5.7 0.17 12.5 1.3 2.0 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 CCD23243.1 - 4.5 7.1 11.4 6.4 6.6 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain B12D PF06522.11 CCD23244.1 - 0.0037 17.0 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit MmgE_PrpD PF03972.14 CCD23245.1 - 3.8e-132 440.9 0.0 4.5e-132 440.7 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Nic96 PF04097.14 CCD23246.1 - 5.1e-196 652.8 0.6 7.5e-196 652.3 0.6 1.2 1 0 0 1 1 1 1 Nup93/Nic96 TFB6 PF17110.5 CCD23246.1 - 0.1 12.3 0.1 0.4 10.4 0.1 2.0 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PPI_Ypi1 PF07491.11 CCD23247.1 - 1.7e-21 75.8 10.7 4.9e-21 74.3 10.7 1.8 1 1 0 1 1 1 1 Protein phosphatase inhibitor Cwf_Cwc_15 PF04889.12 CCD23247.1 - 0.0012 18.6 4.1 0.0014 18.4 4.1 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.9 CCD23247.1 - 0.0023 17.6 9.7 0.003 17.2 9.7 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CCD23247.1 - 0.01 16.5 5.2 0.01 16.5 5.2 1.8 2 1 0 2 2 2 0 Immortalisation up-regulated protein CDC45 PF02724.14 CCD23247.1 - 7.9 4.6 9.3 8.1 4.6 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein JAB PF01398.21 CCD23248.1 - 5.5e-33 113.5 0.9 9.3e-33 112.7 0.1 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CCD23248.1 - 1.3e-10 41.7 1.7 2.4e-10 40.8 1.7 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 CCD23248.1 - 1.5e-07 31.2 0.0 3.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain zf-UBP PF02148.19 CCD23249.1 - 1.2e-06 28.7 0.5 3.9e-06 27.1 0.5 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.29 CCD23249.1 - 2.5e-06 27.2 4.0 5.3e-06 26.1 4.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HTH_Tnp_Tc3_2 PF01498.18 CCD23249.1 - 0.46 10.8 3.0 6.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Transposase Peptidase_M24 PF00557.24 CCD23250.1 - 1.7e-54 184.7 0.0 2.3e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CCD23250.1 - 3.7e-25 88.1 0.0 9.4e-25 86.7 0.0 1.7 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain MCM_N PF14551.6 CCD23250.1 - 0.053 14.1 0.2 0.14 12.8 0.2 1.7 1 0 0 1 1 1 0 MCM N-terminal domain Citrate_synt PF00285.21 CCD23251.1 - 9.6e-88 294.7 0.0 1.2e-87 294.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Hat1_N PF10394.9 CCD23253.1 - 2.4e-40 138.4 2.9 2.4e-40 138.4 2.9 1.7 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 CCD23253.1 - 7.9e-06 26.1 0.0 2.2e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CCD23253.1 - 0.0078 16.6 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CCD23253.1 - 0.061 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EAP30 PF04157.16 CCD23254.1 - 5.7e-58 196.0 0.0 6.4e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Cut8 PF08559.10 CCD23254.1 - 0.071 12.7 0.3 0.1 12.2 0.3 1.2 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein Phage_Mu_Gam PF07352.12 CCD23254.1 - 0.089 12.7 0.2 0.39 10.6 0.2 1.9 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein PseudoU_synth_1 PF01416.20 CCD23255.1 - 6.2e-32 110.3 0.0 1e-28 99.9 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase Sulfate_transp PF00916.20 CCD23256.1 - 5.3e-95 318.4 17.9 7.4e-95 317.9 17.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CCD23256.1 - 6.4e-19 67.7 0.0 1.3e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CCD23256.1 - 0.00077 19.8 6.6 0.00077 19.8 6.6 2.8 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 CCD23256.1 - 0.049 14.0 0.0 0.13 12.6 0.0 1.8 1 1 0 1 1 1 0 STAS domain IstB_IS21 PF01695.17 CCD23256.1 - 0.15 11.7 0.1 0.32 10.7 0.1 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein UPF0242 PF06785.11 CCD23256.1 - 2.2 8.4 5.9 0.32 11.1 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ETF PF01012.21 CCD23257.1 - 7.1e-33 114.0 0.1 1.3e-32 113.2 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 CCD23257.1 - 5.3e-31 106.5 0.1 9.7e-31 105.7 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain PolyA_pol PF01743.20 CCD23259.1 - 1.1e-30 106.6 0.0 2.4e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 CCD23259.1 - 4.5e-06 26.3 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 CCD23259.1 - 0.0096 15.9 3.8 0.054 13.5 3.8 2.3 1 1 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative TRI5 PF06330.11 CCD23259.1 - 0.013 14.3 0.3 0.064 12.1 0.0 2.1 2 0 0 2 2 2 0 Trichodiene synthase (TRI5) JmjC PF02373.22 CCD23260.1 - 3.6e-41 140.2 1.8 3.6e-41 140.2 1.8 3.3 3 0 0 3 3 3 1 JmjC domain, hydroxylase JmjN PF02375.17 CCD23260.1 - 4.3e-15 55.4 3.0 1.4e-14 53.8 3.0 2.0 1 0 0 1 1 1 1 jmjN domain zf-H2C2_2 PF13465.6 CCD23260.1 - 6.9e-07 29.4 10.7 1.9e-06 28.0 7.2 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 CCD23260.1 - 7.7e-05 22.9 15.4 0.013 15.9 2.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.10 CCD23260.1 - 0.005 16.9 2.5 0.01 15.9 2.5 1.5 1 0 0 1 1 1 1 Zinc ribbon domain zf-C2H2_4 PF13894.6 CCD23260.1 - 0.029 15.2 18.6 0.28 12.1 2.4 3.2 3 0 0 3 3 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCD23260.1 - 0.11 12.6 12.1 0.026 14.5 4.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CCD23260.1 - 0.22 11.3 8.9 0.036 13.8 3.6 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zinc_ribbon_5 PF13719.6 CCD23260.1 - 0.4 10.5 1.3 1.1 9.1 1.3 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf_C2H2_ZHX PF18387.1 CCD23260.1 - 4.3 7.0 7.9 0.49 10.1 2.7 2.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 CCD23260.1 - 4.3 7.7 10.7 1.9 8.9 3.2 2.8 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding ADK PF00406.22 CCD23261.1 - 1.2e-42 145.6 0.0 1.5e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CCD23261.1 - 7.6e-18 65.2 0.0 1.6e-17 64.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CCD23261.1 - 1e-13 51.0 1.6 1.4e-13 50.6 0.1 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CCD23261.1 - 2.8e-06 27.9 0.0 4.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CCD23261.1 - 0.0023 18.1 0.0 0.0096 16.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CCD23261.1 - 0.0049 16.3 0.0 0.0072 15.7 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CCD23261.1 - 0.097 13.0 0.0 2.6 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CCD23261.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DEAD_2 PF06733.15 CCD23262.1 - 3.3e-55 186.4 3.7 3.3e-55 186.4 3.7 1.7 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.6 CCD23262.1 - 1.4e-44 152.3 0.1 3.9e-44 150.8 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain HBB PF06777.11 CCD23262.1 - 5.7e-43 146.8 2.0 1.2e-38 132.7 0.4 2.7 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 CCD23262.1 - 0.00066 19.7 0.1 0.023 14.7 0.1 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Sec63 PF02889.16 CCD23263.1 - 6.8e-136 451.5 9.7 9.8e-78 260.9 0.1 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CCD23263.1 - 3.6e-35 121.3 0.0 2.9e-29 102.1 0.0 3.0 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CCD23263.1 - 1.8e-16 60.6 4.4 5.4e-14 52.6 0.0 3.6 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit Helicase_PWI PF18149.1 CCD23263.1 - 7.7e-12 45.4 1.2 7.7e-12 45.4 1.2 2.8 2 0 0 2 2 2 1 N-terminal helicase PWI domain Helicase_C PF00271.31 CCD23263.1 - 1.8e-09 37.9 3.6 2.1e-07 31.2 0.0 4.9 4 1 0 4 4 4 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CCD23263.1 - 0.00045 20.5 0.0 0.0028 17.9 0.0 2.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CCD23264.1 - 3.2e-35 121.7 0.3 3.2e-34 118.5 0.1 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 CCD23264.1 - 9.4e-05 22.9 0.0 0.00024 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CCD23264.1 - 0.0022 17.7 0.1 0.016 14.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 CCD23264.1 - 0.0026 18.2 0.0 0.0083 16.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CCD23264.1 - 0.0053 17.3 0.5 0.028 14.9 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 CCD23264.1 - 0.025 14.8 0.0 0.073 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CCD23264.1 - 0.032 13.6 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CCD23264.1 - 0.033 14.6 0.5 0.28 11.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Cytidylate_kin PF02224.18 CCD23264.1 - 0.035 13.8 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase AAA_7 PF12775.7 CCD23264.1 - 0.064 12.8 0.0 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CCD23264.1 - 0.084 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 CCD23264.1 - 0.089 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain GED PF02212.18 CCD23264.1 - 0.12 12.6 1.7 0.34 11.1 0.5 2.5 2 0 0 2 2 2 0 Dynamin GTPase effector domain AAA_18 PF13238.6 CCD23264.1 - 0.21 12.2 0.0 0.21 12.2 0.0 3.5 3 1 1 4 4 4 0 AAA domain Glutaredoxin PF00462.24 CCD23265.1 - 1.8e-15 56.9 0.0 2.1e-14 53.5 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 CCD23265.1 - 5.2e-13 48.9 0.0 1.3e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 CCD23265.1 - 6.4e-06 26.1 0.0 3.2e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family OST3_OST6 PF04756.13 CCD23265.1 - 0.027 13.8 0.2 0.056 12.8 0.1 1.3 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CCD23265.1 - 0.08 13.3 9.4 0.23 11.8 0.0 3.6 3 2 1 4 4 4 0 Thioredoxin-like Thioredoxin_2 PF13098.6 CCD23265.1 - 0.097 13.1 0.1 3.8 8.0 0.0 3.0 2 2 1 3 3 3 0 Thioredoxin-like domain Methyltransf_25 PF13649.6 CCD23266.1 - 2.6e-11 44.1 0.3 1.3e-10 41.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCD23266.1 - 3e-09 37.4 0.0 5.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCD23266.1 - 1.1e-07 32.5 0.0 1.1e-07 32.5 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCD23266.1 - 2.2e-07 30.8 0.0 3.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCD23266.1 - 6.3e-05 22.9 0.1 0.00011 22.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain CENP-B_dimeris PF09026.10 CCD23266.1 - 0.00025 21.4 4.3 0.00058 20.2 4.3 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Ubie_methyltran PF01209.18 CCD23266.1 - 0.00036 20.0 0.1 0.00056 19.3 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CCD23266.1 - 0.0086 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CCD23266.1 - 0.017 14.8 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SGT1 PF07093.11 CCD23266.1 - 0.057 11.9 1.2 0.074 11.5 1.2 1.1 1 0 0 1 1 1 0 SGT1 protein DUF3605 PF12239.8 CCD23266.1 - 0.059 13.7 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3605) Methyltransf_4 PF02390.17 CCD23266.1 - 0.072 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DUF4611 PF15387.6 CCD23266.1 - 0.66 10.2 5.4 1.3 9.3 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 CCD23266.1 - 1.2 8.4 9.5 2.4 7.4 9.5 1.4 1 0 0 1 1 1 0 NOA36 protein AAA_12 PF13087.6 CCD23267.1 - 8.1e-59 198.6 0.2 8.1e-59 198.6 0.2 2.1 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.6 CCD23267.1 - 2e-36 126.2 0.5 2.8e-19 69.9 0.1 4.4 2 2 1 3 3 2 2 AAA domain AAA_19 PF13245.6 CCD23267.1 - 3.7e-12 46.8 0.0 1.1e-11 45.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCD23267.1 - 1.5e-10 41.1 0.0 2.6e-09 37.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CCD23267.1 - 2.5e-07 30.7 2.3 0.16 11.7 0.0 4.0 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 CCD23267.1 - 1e-05 25.6 1.3 5.4e-05 23.2 0.1 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CCD23267.1 - 3e-05 23.7 0.6 3e-05 23.7 0.6 3.5 3 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain ATPase_2 PF01637.18 CCD23267.1 - 0.00043 20.3 1.6 0.0041 17.1 0.3 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 CCD23267.1 - 0.0041 17.4 0.0 0.028 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 CCD23267.1 - 0.0047 16.4 0.0 0.036 13.5 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.29 CCD23267.1 - 0.012 16.0 0.0 0.047 14.1 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 CCD23267.1 - 0.023 14.5 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Ta0938 PF11494.8 CCD23267.1 - 0.023 15.0 0.9 0.08 13.2 0.9 1.9 1 0 0 1 1 1 0 Ta0938 AAA_7 PF12775.7 CCD23267.1 - 0.044 13.3 4.0 0.12 11.9 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_16 PF13191.6 CCD23267.1 - 0.044 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain 14-3-3 PF00244.20 CCD23268.1 - 1.5e-105 351.7 4.3 1.5e-105 351.7 4.3 1.5 2 0 0 2 2 2 1 14-3-3 protein FlaF PF07309.11 CCD23268.1 - 0.0049 16.9 2.0 0.013 15.5 2.0 1.8 1 0 0 1 1 1 1 Flagellar protein FlaF FRG PF08867.11 CCD23268.1 - 5.3 8.1 6.1 0.81 10.7 0.2 2.5 3 1 0 3 3 3 0 FRG domain E1_dh PF00676.20 CCD23269.1 - 8.1e-122 405.9 0.0 1.2e-121 405.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CCD23269.1 - 0.0043 16.3 0.0 0.0081 15.4 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase ABC_trans_N PF14510.6 CCD23269.1 - 0.011 16.3 1.5 0.13 12.9 0.0 2.5 2 0 0 2 2 2 0 ABC-transporter N-terminal KRTAP7 PF15034.6 CCD23269.1 - 0.044 14.8 3.0 0.72 10.9 0.1 3.2 2 2 1 3 3 3 0 KRTAP type 7 family NOA36 PF06524.12 CCD23269.1 - 2 7.7 6.7 3.1 7.0 3.9 2.1 2 0 0 2 2 2 0 NOA36 protein Presenilin PF01080.17 CCD23269.1 - 2.4 6.8 4.7 3.4 6.3 4.7 1.1 1 0 0 1 1 1 0 Presenilin Rad51 PF08423.11 CCD23270.1 - 1.4e-112 375.1 0.0 1.8e-112 374.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CCD23270.1 - 2.5e-10 40.3 0.1 3.6e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CCD23270.1 - 2.9e-08 33.4 0.1 6.6e-08 32.2 0.1 1.7 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 CCD23270.1 - 7.3e-07 29.0 0.0 1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain CAMSAP_CKK PF08683.11 CCD23270.1 - 0.054 13.6 0.3 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 Microtubule-binding calmodulin-regulated spectrin-associated PAXNEB PF05625.11 CCD23270.1 - 0.18 10.9 0.1 0.35 9.9 0.1 1.4 1 0 0 1 1 1 0 PAXNEB protein EMP70 PF02990.16 CCD23272.1 - 6.8e-194 645.3 9.7 6.8e-194 645.3 9.7 1.3 1 1 0 1 1 1 1 Endomembrane protein 70 Rax2 PF12768.7 CCD23273.1 - 9.9e-54 182.0 0.8 9.9e-54 182.0 0.8 6.5 6 2 1 7 7 7 2 Cortical protein marker for cell polarity PWI PF01480.17 CCD23274.1 - 0.0085 16.4 0.6 0.05 13.9 0.6 2.3 1 0 0 1 1 1 1 PWI domain FOP_dimer PF09398.10 CCD23274.1 - 0.012 15.9 0.2 0.044 14.0 0.2 2.0 1 0 0 1 1 1 0 FOP N terminal dimerisation domain HAD_2 PF13419.6 CCD23274.1 - 7.4 6.6 10.8 6.1 6.9 0.4 3.4 4 0 0 4 4 4 0 Haloacid dehalogenase-like hydrolase Mss4 PF04421.13 CCD23275.1 - 1.2e-20 73.4 1.5 5.9e-20 71.2 1.5 1.8 1 1 0 1 1 1 1 Mss4 protein DEAD PF00270.29 CCD23276.1 - 1.8e-43 148.4 2.4 7.9e-43 146.3 0.3 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD23276.1 - 3.7e-32 111.0 1.7 4.9e-28 97.7 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 CCD23276.1 - 5.7e-06 26.4 4.1 2.2e-05 24.5 0.1 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Mito_carr PF00153.27 CCD23277.1 - 4e-68 225.4 0.4 3.2e-24 84.7 0.1 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 CCD23278.1 - 1.3e-18 67.4 9.0 2.3e-18 66.5 0.3 3.2 2 2 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23278.1 - 3.2e-09 36.5 0.1 7.6e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCD23278.1 - 9.5e-07 27.9 0.0 9.5e-07 27.9 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase WD40 PF00400.32 CCD23279.1 - 0.17 12.8 0.6 63 4.7 0.0 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat Iron_permease PF04120.12 CCD23280.1 - 3.9e-26 91.3 24.0 1.8e-14 53.6 0.8 5.6 6 0 0 6 6 6 5 Low affinity iron permease Tetraspanin PF00335.20 CCD23280.1 - 0.0095 15.7 5.2 0.0095 15.7 5.2 3.2 4 0 0 4 4 4 1 Tetraspanin family MCM_OB PF17207.3 CCD23280.1 - 0.14 12.0 1.3 0.27 11.1 1.3 1.4 1 0 0 1 1 1 0 MCM OB domain PsbJ PF01788.17 CCD23280.1 - 1.1 9.2 9.9 0.096 12.6 2.9 2.6 2 0 0 2 2 2 0 PsbJ HECT PF00632.25 CCD23281.1 - 2.7e-94 316.1 0.0 3.5e-94 315.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CCD23281.1 - 4.5e-34 116.2 22.8 4.3e-12 45.9 1.3 4.1 4 0 0 4 4 4 3 WW domain C2 PF00168.30 CCD23281.1 - 2.9e-20 72.5 0.1 1.3e-19 70.3 0.1 2.2 2 0 0 2 2 2 1 C2 domain Ribosomal_S8e PF01201.22 CCD23282.1 - 7.7e-46 155.7 0.1 1.2e-45 155.0 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3746 PF12562.8 CCD23282.1 - 0.1 12.5 0.2 0.28 11.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) Sas10_Utp3 PF04000.15 CCD23283.1 - 5.1e-12 46.2 2.5 5.1e-12 46.2 2.5 2.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Phlebovirus_G1 PF07243.11 CCD23283.1 - 0.16 10.3 1.3 0.26 9.6 1.3 1.2 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 Vfa1 PF08432.10 CCD23284.1 - 1.5e-41 142.7 6.5 1.7e-41 142.5 6.5 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Aida_C2 PF14186.6 CCD23284.1 - 0.03 14.0 0.0 0.086 12.5 0.0 1.8 2 0 0 2 2 2 0 Cytoskeletal adhesion Prp19 PF08606.11 CCD23284.1 - 0.37 10.8 2.4 0.49 10.4 0.9 1.9 2 0 0 2 2 2 0 Prp19/Pso4-like Mis14 PF08641.12 CCD23284.1 - 0.82 10.0 7.5 12 6.2 7.5 2.2 1 1 0 1 1 1 0 Kinetochore protein Mis14 like DUF334 PF03904.13 CCD23284.1 - 3.8 7.0 7.2 6 6.3 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Pkinase PF00069.25 CCD23285.1 - 1.1e-52 179.0 0.3 6.8e-36 124.0 0.7 3.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23285.1 - 6.2e-26 91.2 0.3 3.9e-23 82.0 0.2 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD23285.1 - 1.6e-05 24.3 0.0 0.0096 15.3 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CCD23285.1 - 0.021 14.7 0.0 0.42 10.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family F-box-like PF12937.7 CCD23286.1 - 1.6e-05 24.7 0.2 2.9e-05 23.9 0.2 1.4 1 0 0 1 1 1 1 F-box-like TPR_8 PF13181.6 CCD23286.1 - 0.0011 19.0 0.3 0.045 14.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat F-box PF00646.33 CCD23286.1 - 0.002 17.9 0.8 0.0047 16.8 0.8 1.6 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 CCD23286.1 - 0.0032 17.2 0.2 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CCD23286.1 - 0.02 15.0 0.1 0.17 12.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 CCD23286.1 - 0.027 14.6 0.1 0.063 13.4 0.1 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 CCD23286.1 - 0.028 14.1 0.1 0.059 13.1 0.1 1.5 1 0 0 1 1 1 0 TPR repeat Fungal_trans PF04082.18 CCD23287.1 - 6.4e-37 127.0 7.3 1.4e-36 125.9 7.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD23287.1 - 5e-10 39.3 8.6 8.7e-10 38.6 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EPSP_synthase PF00275.20 CCD23289.1 - 5.5e-134 447.0 0.3 8.8e-134 446.3 0.1 1.5 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 CCD23289.1 - 4.9e-100 334.0 0.0 7.9e-100 333.3 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 CCD23289.1 - 1.6e-58 198.7 0.0 2.7e-58 197.9 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 CCD23289.1 - 4.4e-36 124.4 0.1 1e-34 119.9 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 CCD23289.1 - 4.2e-20 71.8 0.0 1.2e-19 70.4 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 CCD23289.1 - 8.9e-11 41.4 0.5 1.8e-10 40.4 0.5 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 CCD23289.1 - 5.3e-07 29.8 0.0 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.6 CCD23289.1 - 1.3e-06 28.4 0.0 3.3e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_33 PF13671.6 CCD23289.1 - 0.0072 16.5 0.0 0.13 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain CoA_binding PF02629.19 CCD23289.1 - 0.03 15.0 0.0 0.1 13.3 0.0 1.9 1 0 0 1 1 1 0 CoA binding domain Sacchrp_dh_NADP PF03435.18 CCD23289.1 - 0.035 14.3 0.0 0.53 10.5 0.0 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 6PF2K PF01591.18 CCD23289.1 - 0.045 13.1 0.1 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_14 PF13173.6 CCD23289.1 - 0.058 13.4 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain ComA PF02679.15 CCD23289.1 - 0.075 12.5 0.4 0.88 9.0 0.1 2.8 2 1 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) adh_short PF00106.25 CCD23290.1 - 1.7e-10 40.7 0.0 7.9e-10 38.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCD23290.1 - 0.011 15.3 0.0 0.078 12.5 0.0 2.1 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase CH PF00307.31 CCD23291.1 - 2.2e-82 272.4 1.3 8.1e-21 74.2 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 CCD23291.1 - 2.1e-06 28.1 1.3 2.4e-05 24.7 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair CAMSAP_CH PF11971.8 CCD23291.1 - 2.1e-06 27.5 0.1 0.016 15.1 0.0 3.6 3 0 0 3 3 3 2 CAMSAP CH domain CH_2 PF06294.11 CCD23291.1 - 0.00049 20.1 0.2 0.17 12.0 0.0 3.3 3 1 0 3 3 3 1 CH-like domain in sperm protein EF-hand_1 PF00036.32 CCD23291.1 - 0.11 12.1 0.1 25 4.7 0.0 3.1 3 0 0 3 3 3 0 EF hand ANAPC9 PF12856.7 CCD23292.1 - 1.3e-10 41.5 0.9 1.3e-10 41.5 0.9 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 9 SART-1 PF03343.13 CCD23292.1 - 0.15 10.6 5.4 2.2 6.8 0.0 2.4 2 1 0 2 2 2 0 SART-1 family CDC45 PF02724.14 CCD23293.1 - 1.1e-214 714.4 3.8 1.3e-214 714.2 3.8 1.0 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 CCD23293.1 - 0.0013 18.9 12.1 0.002 18.3 12.1 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Merozoite_SPAM PF07133.11 CCD23293.1 - 0.002 18.2 24.3 0.002 18.2 24.3 2.3 2 0 0 2 2 2 1 Merozoite surface protein (SPAM) SpoIIIAH PF12685.7 CCD23293.1 - 0.021 14.6 5.4 0.044 13.6 5.4 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein SDA1 PF05285.12 CCD23293.1 - 0.04 13.3 17.7 0.062 12.7 17.7 1.2 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 CCD23293.1 - 0.04 12.9 4.0 0.071 12.1 4.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RRN3 PF05327.11 CCD23293.1 - 0.056 12.0 8.8 0.097 11.2 8.8 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Folate_carrier PF01770.18 CCD23293.1 - 0.076 11.7 0.3 1.1 8.0 0.1 2.3 2 0 0 2 2 2 0 Reduced folate carrier BUD22 PF09073.10 CCD23293.1 - 0.12 11.7 15.9 0.17 11.2 15.9 1.2 1 0 0 1 1 1 0 BUD22 IFT57 PF10498.9 CCD23293.1 - 0.12 11.3 11.0 0.19 10.6 11.0 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Nop14 PF04147.12 CCD23293.1 - 0.18 10.0 20.0 0.25 9.5 20.0 1.2 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 CCD23293.1 - 0.19 11.1 14.3 0.29 10.5 14.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FAM176 PF14851.6 CCD23293.1 - 0.68 9.6 10.4 2.5 7.8 10.4 2.0 1 0 0 1 1 1 0 FAM176 family FRQ PF09421.10 CCD23293.1 - 0.89 7.5 9.8 1.3 7.0 9.8 1.1 1 0 0 1 1 1 0 Frequency clock protein GEN1_C PF18380.1 CCD23293.1 - 1.3 10.0 8.6 4.5 8.2 8.6 1.9 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain CDC27 PF09507.10 CCD23293.1 - 7.5 5.8 16.6 12 5.2 16.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sdh5 PF03937.16 CCD23294.1 - 3.8e-25 87.7 0.8 6.6e-25 86.9 0.8 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase PCI PF01399.27 CCD23295.1 - 6.5e-07 29.8 0.0 2.4e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 PCI domain Smg4_UPF3 PF03467.15 CCD23296.1 - 2.2e-28 99.4 1.0 2.2e-28 99.4 1.0 3.8 2 2 1 3 3 3 1 Smg-4/UPF3 family Dsh_C PF12316.8 CCD23296.1 - 8.2 6.8 24.5 1.4 9.3 9.3 2.4 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal LSM PF01423.22 CCD23297.1 - 5.2e-22 77.3 0.1 1e-21 76.4 0.1 1.5 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CCD23297.1 - 0.0038 17.3 0.1 0.0064 16.6 0.1 1.6 1 1 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CCD23297.1 - 0.097 12.8 0.2 0.28 11.3 0.2 1.7 1 1 0 1 1 1 0 Scd6-like Sm domain E1-E2_ATPase PF00122.20 CCD23300.1 - 3.7e-49 166.7 6.6 1.1e-48 165.1 5.1 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CCD23300.1 - 8.4e-19 68.7 1.9 8.4e-19 68.7 0.1 2.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CCD23300.1 - 3.2e-10 39.6 0.0 3.2e-10 39.6 0.0 2.2 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CCD23300.1 - 0.00011 22.2 0.1 0.00023 21.2 0.1 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CCD23300.1 - 0.0047 16.7 0.1 0.0047 16.7 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase UreE_N PF02814.15 CCD23300.1 - 0.099 12.3 0.0 6.1 6.5 0.0 2.6 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain Transp_cyt_pur PF02133.15 CCD23301.1 - 4.1e-16 58.8 29.4 4.5e-16 58.6 25.7 2.0 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin UPF0139 PF03669.13 CCD23301.1 - 0.8 9.6 4.4 1.2 9.1 0.0 3.4 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0139) COX5B PF01215.19 CCD23302.1 - 5.2e-63 210.5 0.0 6.5e-63 210.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb WD40 PF00400.32 CCD23303.1 - 6.1e-14 52.2 4.1 0.0046 17.8 0.1 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD23303.1 - 0.00011 22.5 0.2 5.6 7.3 0.0 5.0 4 2 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain bPH_3 PF14470.6 CCD23303.1 - 0.05 14.0 3.0 0.49 10.8 1.7 2.9 2 0 0 2 2 2 0 Bacterial PH domain HSDR_N_2 PF13588.6 CCD23303.1 - 0.12 12.4 0.6 0.31 11.1 0.2 1.9 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) COX6A PF02046.15 CCD23304.1 - 1.8e-36 125.0 0.3 1.9e-36 124.9 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa MT-A70 PF05063.14 CCD23305.1 - 4.1e-57 192.8 0.2 8.4e-57 191.8 0.2 1.6 1 0 0 1 1 1 1 MT-A70 Hist_deacetyl PF00850.19 CCD23306.1 - 7.5e-83 278.5 0.0 9.2e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain HEAT_EZ PF13513.6 CCD23307.1 - 1.2e-30 105.5 13.7 0.00031 21.2 0.0 14.7 11 3 5 16 16 16 5 HEAT-like repeat HEAT PF02985.22 CCD23307.1 - 2.2e-28 95.9 19.9 0.02 15.1 0.0 18.9 22 0 0 22 22 19 5 HEAT repeat HEAT_2 PF13646.6 CCD23307.1 - 9.6e-26 90.0 14.6 0.00068 20.0 0.1 12.3 9 2 6 15 15 14 7 HEAT repeats Gcn1_N PF12074.8 CCD23307.1 - 1.7e-21 77.0 8.2 8.1e-12 45.1 0.0 5.4 6 0 0 6 6 6 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Cnd1 PF12717.7 CCD23307.1 - 1.9e-15 57.3 19.8 1 9.4 0.0 13.3 8 4 6 14 14 13 4 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CCD23307.1 - 3.3e-15 56.3 2.0 0.002 17.7 0.0 8.7 9 1 0 10 10 10 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 CCD23307.1 - 2.6e-14 53.6 0.8 0.068 13.8 0.0 9.3 8 1 0 8 8 7 3 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 CCD23307.1 - 0.00023 21.1 15.0 0.79 9.6 0.0 9.7 9 3 0 9 9 9 1 Domain of unknown function (DUF3385) ParcG PF10274.9 CCD23307.1 - 0.073 13.2 5.6 13 5.9 0.0 5.9 6 1 1 7 7 7 0 Parkin co-regulated protein BP28CT PF08146.12 CCD23307.1 - 0.073 12.9 3.6 1.5 8.6 0.0 4.1 3 0 0 3 3 3 0 BP28CT (NUC211) domain AAA_16 PF13191.6 CCD23307.1 - 0.86 10.0 3.3 5.1 7.4 0.1 3.9 4 0 0 4 4 4 0 AAA ATPase domain RTP1_C1 PF10363.9 CCD23307.1 - 1 9.6 5.1 3.1e+02 1.6 0.0 6.5 6 1 1 7 7 7 0 Required for nuclear transport of RNA pol II C-terminus 1 FANCI_S2 PF14676.6 CCD23307.1 - 6.1 7.1 12.0 0.22 11.8 0.1 4.6 5 0 0 5 5 5 0 FANCI solenoid 2 HEAT_PBS PF03130.16 CCD23307.1 - 7.6 7.5 6.8 1.3e+02 3.7 0.1 5.3 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat D-ser_dehydrat PF14031.6 CCD23308.1 - 5.7e-19 68.6 0.0 1.3e-18 67.4 0.0 1.6 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 CCD23308.1 - 2.4e-07 30.6 0.0 3.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Kelch_4 PF13418.6 CCD23309.1 - 5.6e-11 42.3 8.7 0.0092 16.0 0.0 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CCD23309.1 - 7.1e-11 42.0 2.2 3.7e-06 27.0 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 CCD23309.1 - 1.1e-09 37.7 0.1 0.012 15.1 0.0 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 CCD23309.1 - 3e-06 27.0 0.5 0.0011 18.8 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 CCD23309.1 - 1.5e-05 25.2 0.2 0.25 11.7 0.0 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CCD23309.1 - 3.1e-05 23.8 1.4 0.012 15.6 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Yip1 PF04893.17 CCD23310.1 - 1.5e-10 41.0 4.5 2.2e-10 40.5 4.5 1.2 1 0 0 1 1 1 1 Yip1 domain DUF3337 PF11816.8 CCD23311.1 - 6.3e-28 97.8 0.1 1.7e-27 96.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 CCD23311.1 - 3.5e-06 27.6 8.7 0.31 12.0 0.3 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat SOAR PF16533.5 CCD23311.1 - 0.014 15.4 1.7 0.082 12.9 0.6 2.4 2 0 0 2 2 2 0 STIM1 Orai1-activating region MbeB_N PF04837.12 CCD23311.1 - 0.18 12.2 1.6 0.57 10.5 1.6 1.9 1 0 0 1 1 1 0 MbeB-like, N-term conserved region mRNA_decap_C PF16741.5 CCD23311.1 - 2 7.8 4.2 0.44 9.9 0.3 1.9 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus CENP-S PF15630.6 CCD23312.1 - 1.6e-24 86.0 0.0 2.1e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CCD23312.1 - 1.9e-09 37.6 0.0 2.2e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CCD23312.1 - 4.6e-05 23.8 0.0 5.4e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CCD23312.1 - 0.014 15.4 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CCD23312.1 - 0.048 13.7 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated RNA_pol_Rpb6 PF01192.22 CCD23313.1 - 0.18 11.7 0.7 0.38 10.7 0.7 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb6 RSN1_7TM PF02714.15 CCD23314.1 - 3.6e-88 295.5 20.8 3.6e-88 295.5 20.8 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CCD23314.1 - 1e-42 145.5 5.3 2.5e-41 141.0 3.5 3.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 CCD23314.1 - 1.5e-26 92.4 0.6 4.1e-26 91.0 0.6 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 CCD23314.1 - 1.4e-24 87.3 0.7 2.2e-24 86.6 0.7 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter ATG19_autophagy PF12744.7 CCD23315.1 - 2.8e-20 72.6 1.8 5.3e-20 71.7 0.7 2.0 2 0 0 2 2 2 1 Autophagy protein Atg19, Atg8-binding RasGAP PF00616.19 CCD23317.1 - 7.6e-21 74.8 2.2 3.3e-12 46.5 0.3 3.5 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase ParcG PF10274.9 CCD23317.1 - 0.029 14.5 0.8 0.16 12.1 0.8 2.3 1 0 0 1 1 1 0 Parkin co-regulated protein RNase_T PF00929.24 CCD23318.1 - 5.4e-19 69.3 0.3 1.2e-18 68.2 0.0 1.7 2 1 0 2 2 2 1 Exonuclease CRIM PF16978.5 CCD23319.1 - 4.8e-34 117.5 0.2 4e-33 114.5 0.1 2.6 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 CCD23319.1 - 2.3e-31 108.3 6.0 1.1e-30 106.2 0.5 3.3 3 0 0 3 3 3 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 CCD23319.1 - 0.036 14.3 1.1 0.12 12.6 0.2 2.3 2 0 0 2 2 2 0 TUG ubiquitin-like domain ATP19 PF11022.8 CCD23320.1 - 3.7e-22 78.5 0.0 4e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit K MKT1_N PF12247.8 CCD23320.1 - 0.042 14.2 0.0 0.048 14.0 0.0 1.0 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication Brix PF04427.18 CCD23321.1 - 6.5e-40 137.3 0.1 9e-40 136.8 0.1 1.2 1 0 0 1 1 1 1 Brix domain Nucleopor_Nup85 PF07575.13 CCD23321.1 - 0.1 11.1 0.1 0.13 10.8 0.1 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin ABC_tran PF00005.27 CCD23322.1 - 3.1e-52 176.7 1.0 3e-25 89.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 CCD23322.1 - 4.4e-41 140.6 24.0 6.3e-26 91.1 9.9 2.6 3 0 0 3 3 2 2 ABC-2 type transporter AAA_21 PF13304.6 CCD23322.1 - 3e-10 40.4 11.3 0.00031 20.6 0.1 4.5 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CCD23322.1 - 5.7e-09 36.1 5.9 0.00016 21.6 0.2 3.1 2 1 1 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 CCD23322.1 - 1.2e-08 35.5 0.0 0.0035 17.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 CCD23322.1 - 3.7e-06 26.5 11.9 3.2e-05 23.5 0.4 3.9 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 CCD23322.1 - 4.4e-06 27.3 0.2 0.18 12.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CCD23322.1 - 4.6e-06 26.9 1.3 0.24 11.7 0.0 3.8 2 1 1 3 3 3 2 AAA domain NACHT PF05729.12 CCD23322.1 - 6.2e-06 26.2 0.1 0.024 14.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 CCD23322.1 - 7.8e-06 26.0 0.3 0.063 13.4 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 CCD23322.1 - 8.1e-06 25.1 0.4 0.066 12.3 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 CCD23322.1 - 9.8e-06 25.2 7.0 0.0086 15.8 0.1 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain Rad17 PF03215.15 CCD23322.1 - 1.2e-05 25.3 0.2 0.016 15.1 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 CCD23322.1 - 1.3e-05 24.8 0.1 0.021 14.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 CCD23322.1 - 0.00011 22.6 0.2 0.82 10.1 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 CCD23322.1 - 0.00012 22.4 0.1 0.11 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCD23322.1 - 0.00028 20.6 0.7 0.66 9.7 0.4 2.3 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CCD23322.1 - 0.00095 19.2 0.1 0.52 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 CCD23322.1 - 0.001 19.6 10.7 0.023 15.2 0.2 3.4 2 1 1 3 3 2 2 AAA domain cobW PF02492.19 CCD23322.1 - 0.0011 18.6 0.5 0.69 9.5 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 CCD23322.1 - 0.0011 19.4 2.5 1.2 9.5 0.1 3.4 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 CCD23322.1 - 0.0018 18.3 1.9 0.32 10.9 0.0 3.0 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 CCD23322.1 - 0.0027 17.0 0.1 1.2 8.3 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain Pox_A32 PF04665.12 CCD23322.1 - 0.0043 16.5 0.2 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_24 PF13479.6 CCD23322.1 - 0.0056 16.4 1.3 2.9 7.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 CCD23322.1 - 0.007 16.3 2.7 3.5 7.5 0.4 3.1 3 0 0 3 3 3 1 NTPase AAA_33 PF13671.6 CCD23322.1 - 0.0089 16.2 0.1 5.1 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CCD23322.1 - 0.0099 16.2 0.4 0.41 11.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 CCD23322.1 - 0.011 15.5 0.5 3.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.18 CCD23322.1 - 0.013 14.8 1.7 0.91 8.8 0.2 2.8 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_14 PF13173.6 CCD23322.1 - 0.014 15.4 0.1 7 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CCD23322.1 - 0.015 15.7 1.8 9.1 6.7 0.0 3.7 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CCD23322.1 - 0.017 14.3 5.0 1.1 8.3 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain Cytidylate_kin PF02224.18 CCD23322.1 - 0.023 14.4 1.9 1 9.0 0.0 3.3 4 0 0 4 4 3 0 Cytidylate kinase SbcCD_C PF13558.6 CCD23322.1 - 0.028 14.7 0.5 22 5.4 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit dNK PF01712.19 CCD23322.1 - 0.03 14.2 0.2 7.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF2791 PF10923.8 CCD23322.1 - 0.047 12.5 0.1 4.4 6.0 0.0 2.3 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) Adeno_IVa2 PF02456.15 CCD23322.1 - 0.11 11.3 0.8 0.15 10.8 0.0 1.5 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATPase PF06745.13 CCD23322.1 - 0.11 11.8 3.3 1.2 8.4 0.0 3.7 5 0 0 5 5 5 0 KaiC ABC_ATPase PF09818.9 CCD23322.1 - 0.11 11.3 0.8 4.9 5.8 0.3 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class ATP_bind_1 PF03029.17 CCD23322.1 - 0.11 12.2 3.3 8.1 6.1 0.1 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CCD23322.1 - 0.12 11.6 0.5 7.9 5.7 0.4 2.3 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.9 CCD23322.1 - 0.17 11.1 0.2 1.2 8.3 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.14 CCD23322.1 - 0.25 11.2 1.4 3.1 7.7 0.4 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.20 CCD23322.1 - 0.26 11.1 1.0 5.4 6.9 0.2 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase SRPRB PF09439.10 CCD23322.1 - 2.7 7.4 8.2 3.9 6.9 0.1 3.1 4 0 0 4 4 3 0 Signal recognition particle receptor beta subunit ABC2_membrane_3 PF12698.7 CCD23322.1 - 4 6.5 31.4 0.41 9.7 5.9 2.7 2 0 0 2 2 2 0 ABC-2 family transporter protein Septin PF00735.18 CCD23322.1 - 7.4 5.8 8.0 11 5.2 0.1 3.1 3 0 0 3 3 3 0 Septin AAA_13 PF13166.6 CCD23322.1 - 9.1 4.8 10.3 0.89 8.1 0.1 3.7 5 0 0 5 5 5 0 AAA domain AcetylCoA_hydro PF02550.15 CCD23324.1 - 2e-70 236.8 0.0 6.9e-70 235.0 0.0 1.9 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 CCD23324.1 - 1.9e-40 138.3 0.0 2.9e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CitF PF04223.12 CCD23324.1 - 0.053 12.4 0.0 0.094 11.6 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) CoA_trans PF01144.23 CCD23324.1 - 0.073 12.5 0.0 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 Coenzyme A transferase Pkinase PF00069.25 CCD23325.1 - 1.8e-68 230.8 0.0 2.2e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23325.1 - 7e-32 110.7 0.0 9.2e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCD23325.1 - 0.0015 17.6 2.1 0.004 16.2 2.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CCD23325.1 - 0.0031 16.9 0.3 0.0049 16.3 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 CCD23325.1 - 0.05 12.4 0.2 0.069 12.0 0.2 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kinase-like PF14531.6 CCD23325.1 - 0.095 12.0 0.1 0.21 10.9 0.1 1.6 1 1 0 1 1 1 0 Kinase-like Sortilin-Vps10 PF15902.5 CCD23326.1 - 2.3e-209 695.8 19.4 3.1e-142 474.5 4.9 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CCD23326.1 - 2.9e-71 239.3 11.3 5.9e-38 130.9 0.9 2.5 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CCD23326.1 - 1.7e-11 42.3 46.7 0.21 11.7 0.1 13.0 13 0 0 13 13 13 6 BNR/Asp-box repeat BNR_2 PF13088.6 CCD23326.1 - 1.2e-05 24.7 4.5 0.11 11.7 0.2 4.8 4 1 0 4 4 4 2 BNR repeat-like domain CHB_HEX_C PF03174.13 CCD23326.1 - 0.0013 18.7 5.5 3.5 7.7 0.0 5.3 5 0 0 5 5 5 2 Chitobiase/beta-hexosaminidase C-terminal domain Mo-co_dimer PF03404.16 CCD23326.1 - 0.0098 15.9 2.3 11 6.0 0.0 4.8 6 0 0 6 6 6 1 Mo-co oxidoreductase dimerisation domain DUF2147 PF09917.9 CCD23326.1 - 0.18 12.5 0.7 4 8.1 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2147) Exo_endo_phos PF03372.23 CCD23328.1 - 3e-12 46.6 0.0 6.2e-12 45.5 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 CCD23328.1 - 2.5e-10 40.3 3.8 3.3e-10 39.9 0.3 2.6 3 0 0 3 3 3 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 CCD23328.1 - 0.0021 17.9 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Rft-1 PF04506.13 CCD23329.1 - 2.7e-219 729.1 47.5 3.1e-219 729.0 47.5 1.0 1 0 0 1 1 1 1 Rft protein MatE PF01554.18 CCD23329.1 - 0.00095 18.9 4.7 0.00095 18.9 4.7 3.7 4 1 0 4 4 4 1 MatE CBFD_NFYB_HMF PF00808.23 CCD23330.1 - 2e-26 92.0 0.0 3.1e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CCD23330.1 - 1.7e-05 25.2 0.2 2.6e-05 24.6 0.0 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CCD23330.1 - 0.0089 16.1 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 CCD23330.1 - 0.017 15.6 0.2 0.078 13.5 0.0 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Lon_C PF05362.13 CCD23331.1 - 2e-67 226.7 0.0 1.4e-66 224.0 0.0 2.5 3 0 0 3 3 3 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 CCD23331.1 - 5e-37 127.8 3.2 1.8e-36 126.0 3.2 2.0 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 CCD23331.1 - 2.6e-23 82.9 0.0 9.4e-23 81.1 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CCD23331.1 - 4e-07 30.3 0.0 1.9e-06 28.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CCD23331.1 - 7.8e-07 29.2 0.0 1.8e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 CCD23331.1 - 1e-05 25.4 0.0 2.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 CCD23331.1 - 0.00019 21.7 0.0 0.0046 17.2 0.0 2.9 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 CCD23331.1 - 0.00067 18.7 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 CCD23331.1 - 0.002 17.9 0.0 0.01 15.6 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CCD23331.1 - 0.0022 18.5 0.8 0.012 16.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CCD23331.1 - 0.0023 18.3 0.0 0.09 13.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 CCD23331.1 - 0.0025 17.6 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 CCD23331.1 - 0.0031 17.9 0.1 0.016 15.6 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 CCD23331.1 - 0.0047 16.9 0.0 0.02 15.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CCD23331.1 - 0.05 13.5 0.0 0.22 11.4 0.0 2.1 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 CCD23331.1 - 0.063 13.2 0.6 1.4 8.8 0.1 3.0 2 1 1 3 3 3 0 NTPase TsaE PF02367.17 CCD23331.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SKI PF01202.22 CCD23331.1 - 0.088 12.9 2.1 0.12 12.5 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase AAA_7 PF12775.7 CCD23331.1 - 0.15 11.6 0.3 0.44 10.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region DNTTIP1_dimer PF18192.1 CCD23331.1 - 0.15 12.4 3.9 17 5.8 0.0 3.9 3 1 1 4 4 4 0 DNTTIP1 dimerisation domain ClpB_D2-small PF10431.9 CCD23331.1 - 1.8 8.6 6.2 0.25 11.4 0.1 2.7 3 0 0 3 3 2 0 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 CCD23332.1 - 3.6e-102 340.2 0.0 5.6e-102 339.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCD23332.1 - 2.5e-36 124.3 0.0 4.9e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCD23332.1 - 2.7e-26 91.8 0.2 6.8e-26 90.5 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 CCD23332.1 - 2e-23 83.4 34.8 2e-23 83.4 34.8 4.0 5 0 0 5 5 5 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 CCD23332.1 - 2.9e-12 47.1 0.0 8.6e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CCD23332.1 - 2.8e-09 36.7 0.0 2.8e-07 30.1 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CCD23332.1 - 1.5e-07 31.5 0.0 3.9e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CCD23332.1 - 0.00029 20.7 0.0 0.0015 18.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCD23332.1 - 0.0023 17.7 0.1 0.017 14.9 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 CCD23332.1 - 0.023 15.1 0.0 0.076 13.4 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CCD23332.1 - 0.059 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain SelR PF01641.18 CCD23332.1 - 0.1 12.7 0.1 1.9 8.6 0.1 2.3 2 0 0 2 2 2 0 SelR domain Methyltr_RsmB-F PF01189.17 CCD23333.1 - 9.2e-44 149.5 0.0 4.3e-43 147.3 0.0 1.9 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CCD23333.1 - 0.00047 20.3 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Nitr_red_alph_N PF14710.6 CCD23333.1 - 0.55 10.7 3.7 0.75 10.3 1.5 2.2 2 0 0 2 2 2 0 Respiratory nitrate reductase alpha N-terminal UAF_Rrn10 PF05234.11 CCD23334.1 - 1.2e-46 157.9 0.1 1.5e-46 157.5 0.1 1.1 1 0 0 1 1 1 1 UAF complex subunit Rrn10 GDI PF00996.18 CCD23335.1 - 1.1e-223 742.6 0.3 1.3e-223 742.2 0.3 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CCD23335.1 - 0.0027 17.9 0.0 0.0057 16.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Ribosomal_S15 PF00312.22 CCD23336.1 - 1.9e-15 56.8 0.2 2e-15 56.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 RPAP2_Rtr1 PF04181.13 CCD23337.1 - 4.6e-17 62.1 1.2 6.8e-17 61.6 0.3 1.8 2 0 0 2 2 2 1 Rtr1/RPAP2 family DAHP_snth_FXD PF18152.1 CCD23337.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain DUF747 PF05346.11 CCD23338.1 - 8.4e-80 268.6 21.9 1.4e-79 267.9 21.9 1.3 1 0 0 1 1 1 1 Eukaryotic membrane protein family COX15-CtaA PF02628.15 CCD23339.1 - 6.1e-116 387.0 4.7 7.4e-116 386.7 4.7 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF3624 PF12292.8 CCD23339.1 - 0.79 10.2 3.2 0.38 11.2 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) HhH-GPD PF00730.25 CCD23340.1 - 4.4e-09 36.8 0.0 8.7e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4211 PF13926.6 CCD23340.1 - 0.18 11.8 2.0 3.6 7.6 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4211) Sugar_tr PF00083.24 CCD23341.1 - 9e-160 532.4 39.4 1.1e-159 532.2 39.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD23341.1 - 3.2e-26 92.1 33.7 4.2e-26 91.7 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Copper-fist PF00649.18 CCD23342.1 - 1.3e-21 75.8 0.6 2.5e-21 74.9 0.6 1.5 1 0 0 1 1 1 1 Copper fist DNA binding domain zf-C2H2 PF00096.26 CCD23343.1 - 3.6e-08 33.4 4.2 0.0043 17.4 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD23343.1 - 1.3e-05 25.6 7.6 0.0043 17.8 0.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCD23343.1 - 0.0019 18.6 10.0 0.0037 17.6 0.3 4.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 CCD23343.1 - 0.0024 18.2 1.4 0.44 11.0 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type FOXP-CC PF16159.5 CCD23343.1 - 0.006 17.2 1.2 0.042 14.5 0.3 2.7 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CCD23343.1 - 0.023 15.0 0.3 3.9 7.9 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CCD23343.1 - 0.059 13.7 0.9 0.16 12.3 0.9 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CCD23343.1 - 0.096 13.0 1.7 0.17 12.3 0.6 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-tcix PF14952.6 CCD23343.1 - 0.22 11.1 1.1 13 5.5 0.1 2.4 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding MUG113 PF13455.6 CCD23344.1 - 1.8e-08 34.9 0.1 2.1e-07 31.5 0.1 2.6 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 CCD23344.1 - 1e-07 32.4 0.1 1.5e-05 25.5 0.1 2.5 1 1 0 1 1 1 1 T5orf172 domain adh_short PF00106.25 CCD23345.1 - 0.0002 20.9 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCD23345.1 - 0.18 11.3 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase LUC7 PF03194.15 CCD23346.1 - 2.8e-55 187.7 7.8 4.1e-55 187.2 7.8 1.2 1 0 0 1 1 1 1 LUC7 N_terminus PLATZ PF04640.14 CCD23346.1 - 0.063 13.9 0.6 0.16 12.6 0.6 1.6 1 0 0 1 1 1 0 PLATZ transcription factor FAM24 PF15193.6 CCD23346.1 - 0.082 13.7 0.2 0.17 12.7 0.2 1.5 1 0 0 1 1 1 0 FAM24 family KIF1B PF12423.8 CCD23346.1 - 1.8 9.0 3.8 1.8 9.1 1.2 2.4 3 0 0 3 3 3 0 Kinesin protein 1B DUF2418 PF10332.9 CCD23347.1 - 4.4e-24 84.8 2.4 4.4e-24 84.8 2.4 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) SBDS PF01172.18 CCD23347.1 - 0.025 14.7 0.5 0.089 12.9 0.1 2.1 2 0 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Prenyltrans PF00432.21 CCD23348.1 - 1.6e-41 139.7 7.3 1e-12 47.5 0.0 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CCD23348.1 - 0.036 13.2 0.0 0.12 11.4 0.0 1.8 1 1 1 2 2 2 0 Squalene-hopene cyclase N-terminal domain FliG_N PF14842.6 CCD23348.1 - 0.054 14.0 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 FliG N-terminal domain UBX PF00789.20 CCD23349.1 - 1.5e-09 38.0 0.0 4.1e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 UBX domain CDT1 PF08839.11 CCD23349.1 - 0.14 12.4 3.8 0.23 11.8 3.8 1.3 1 0 0 1 1 1 0 DNA replication factor CDT1 like SRP14 PF02290.15 CCD23350.1 - 7e-25 87.2 0.1 1.2e-24 86.5 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle 14kD protein ParB PF08775.10 CCD23350.1 - 0.03 14.8 1.0 0.034 14.6 0.2 1.5 2 0 0 2 2 2 0 ParB family LigT_PEase PF02834.16 CCD23350.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 LigT like Phosphoesterase PMT PF02366.18 CCD23351.1 - 7.7e-71 238.5 24.6 1.2e-70 237.9 24.6 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCD23351.1 - 2e-49 167.9 7.1 2e-49 167.9 7.1 2.4 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCD23351.1 - 4.7e-36 124.4 1.1 4.7e-36 124.4 1.1 1.7 2 0 0 2 2 2 1 MIR domain PMT_2 PF13231.6 CCD23351.1 - 2.4e-05 24.6 16.8 2.4e-05 24.6 16.8 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF1223 PF06764.11 CCD23351.1 - 0.16 12.0 3.5 0.27 11.2 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) PMT PF02366.18 CCD23352.1 - 7.3e-85 284.4 17.7 7.3e-85 284.4 17.7 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCD23352.1 - 1.7e-60 204.0 19.0 1.7e-60 204.0 19.0 1.8 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCD23352.1 - 7.4e-47 159.6 0.1 1.2e-46 158.9 0.1 1.3 1 0 0 1 1 1 1 MIR domain DNA_pol_B PF00136.21 CCD23353.1 - 6.3e-145 483.4 0.6 8.9e-145 482.9 0.6 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CCD23353.1 - 2.3e-86 290.0 0.0 4.8e-86 289.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CCD23353.1 - 4.9e-18 65.4 4.8 1.1e-17 64.2 4.8 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CCD23353.1 - 1.5e-05 24.1 0.2 0.00052 19.0 0.0 2.5 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 CCD23353.1 - 0.00064 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Pkinase PF00069.25 CCD23354.1 - 4.5e-71 239.3 0.1 5.8e-71 238.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23354.1 - 1.7e-37 129.1 0.0 2.2e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CCD23354.1 - 2.1e-17 63.2 0.8 5.3e-17 61.9 0.8 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CCD23354.1 - 7.5e-08 32.6 0.0 2.5e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 CCD23354.1 - 7e-06 25.1 0.0 9.4e-06 24.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CCD23354.1 - 0.0021 17.7 0.8 0.1 12.2 0.1 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CCD23354.1 - 0.0068 15.8 0.2 0.01 15.2 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCD23354.1 - 0.038 13.3 1.8 6 6.1 0.2 2.6 2 1 1 3 3 3 0 Kinase-like YrbL-PhoP_reg PF10707.9 CCD23354.1 - 0.087 12.3 2.4 0.33 10.4 2.4 1.9 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 CCD23354.1 - 0.099 12.2 2.3 1.1 8.8 2.3 2.2 1 1 0 1 1 1 0 RIO1 family ArsA_ATPase PF02374.15 CCD23355.1 - 4.8e-117 390.5 0.1 5.6e-117 390.3 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CCD23355.1 - 9.9e-10 38.6 0.8 7.1e-09 35.8 0.1 2.5 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 CCD23355.1 - 4.3e-09 36.5 0.0 8.3e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 CCD23355.1 - 0.0011 18.5 1.4 0.0085 15.6 0.5 2.5 2 1 1 3 3 3 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 CCD23355.1 - 0.0011 18.5 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 CCD23355.1 - 0.018 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CCD23355.1 - 0.027 14.1 0.0 0.7 9.5 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PhoH PF02562.16 CCD23355.1 - 0.06 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 CCD23355.1 - 0.082 12.6 0.2 0.54 9.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain STI1 PF17830.1 CCD23355.1 - 0.092 12.7 0.8 9.1 6.3 0.0 2.6 2 0 0 2 2 2 0 STI1 domain Lebercilin PF15619.6 CCD23356.1 - 0.0013 18.5 13.3 0.0013 18.5 13.3 2.3 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease FlpD PF02662.16 CCD23356.1 - 0.074 13.1 0.6 0.074 13.1 0.6 2.9 2 1 2 4 4 4 0 Methyl-viologen-reducing hydrogenase, delta subunit CCDC74_C PF14917.6 CCD23356.1 - 0.16 12.5 0.1 0.16 12.5 0.1 3.3 3 1 1 4 4 4 0 Coiled coil protein 74, C terminal DUF4239 PF14023.6 CCD23356.1 - 0.45 10.2 1.2 0.99 9.1 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) zf-met PF12874.7 CCD23357.1 - 6e-06 26.5 1.2 1.4e-05 25.3 1.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCD23357.1 - 4.7e-05 23.6 1.5 9.7e-05 22.6 1.5 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CCD23357.1 - 0.028 15.2 0.6 0.075 13.9 0.6 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger SNRNP27 PF08648.12 CCD23357.1 - 0.033 14.3 0.3 0.033 14.3 0.3 2.2 3 0 0 3 3 3 0 U4/U6.U5 small nuclear ribonucleoproteins zf-C2H2 PF00096.26 CCD23357.1 - 0.064 13.7 2.3 0.16 12.5 2.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3953 PF13129.6 CCD23357.1 - 0.15 11.8 0.2 0.4 10.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) RPN6_N PF18055.1 CCD23358.1 - 5.6e-39 133.1 3.6 5.6e-39 133.1 3.6 2.9 3 1 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CCD23358.1 - 1.5e-16 60.8 2.1 2.4e-16 60.2 0.0 2.4 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 CCD23358.1 - 1.6e-09 37.3 0.6 1.3e-08 34.4 0.2 2.6 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_20 PF14561.6 CCD23358.1 - 8e-05 22.9 4.1 0.018 15.4 0.4 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCD23358.1 - 8.6e-05 22.8 6.7 0.0016 18.7 0.5 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 CCD23358.1 - 0.00011 21.6 1.8 0.00022 20.6 1.8 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 CCD23358.1 - 0.00082 20.0 0.2 0.015 16.0 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Rsbr_N PF08678.10 CCD23358.1 - 0.021 14.9 2.4 0.042 13.9 0.7 2.4 2 0 0 2 2 2 0 Rsbr N terminal FRB_dom PF08771.11 CCD23358.1 - 0.12 12.7 2.7 0.57 10.6 0.7 3.0 2 1 0 2 2 2 0 FKBP12-rapamycin binding domain HMW1C_N PF18071.1 CCD23358.1 - 0.13 12.0 3.4 0.12 12.2 0.4 2.5 2 1 2 4 4 4 0 HMW1C N-terminal TPR_MalT PF17874.1 CCD23358.1 - 0.15 11.4 1.0 0.23 10.8 0.8 1.4 1 1 0 1 1 1 0 MalT-like TPR region TPR_2 PF07719.17 CCD23358.1 - 0.21 11.8 13.7 0.86 9.9 0.3 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 CCD23358.1 - 0.4 11.2 6.4 8.1 7.0 0.1 4.1 2 2 2 4 4 4 0 Tetratricopeptide repeat DUF4606 PF15379.6 CCD23358.1 - 1.1 9.5 4.2 1.5 9.1 1.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4606) Syntaxin_2 PF14523.6 CCD23358.1 - 1.7 9.1 8.4 0.8 10.1 1.2 3.1 3 0 0 3 3 3 0 Syntaxin-like protein UDPGP PF01704.18 CCD23359.1 - 1.2e-46 159.2 0.0 1.6e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CCD23359.1 - 0.2 12.0 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain LisH PF08513.11 CCD23360.1 - 5.5e-06 26.1 3.5 1.1e-05 25.1 3.5 1.6 1 0 0 1 1 1 1 LisH Peptidase_M22 PF00814.25 CCD23361.1 - 9.1e-58 196.1 0.0 1.1e-57 195.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family BcrAD_BadFG PF01869.20 CCD23361.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Nse4_C PF08743.10 CCD23362.1 - 1e-29 102.6 1.8 1e-29 102.6 1.8 2.3 3 0 0 3 3 3 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 CCD23362.1 - 1.5e-14 53.8 0.2 1.5e-14 53.8 0.2 2.6 3 1 0 3 3 3 1 Binding domain of Nse4/EID3 to Nse3-MAGE Homeodomain PF00046.29 CCD23363.1 - 2.3e-16 59.4 4.1 4.3e-16 58.5 4.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CCD23363.1 - 0.0044 16.9 0.9 0.012 15.5 0.9 1.8 1 0 0 1 1 1 1 Homeobox KN domain TLP-20 PF06088.11 CCD23363.1 - 0.0044 16.9 10.8 0.0044 16.9 10.8 4.3 4 0 0 4 4 4 3 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) HOCHOB PF17943.1 CCD23363.1 - 0.089 13.5 1.0 0.22 12.2 1.0 1.6 1 0 0 1 1 1 0 Homeobox-cysteine loop-homeobox TPR_2 PF07719.17 CCD23364.1 - 1.9e-07 30.7 8.0 0.0061 16.6 0.3 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 CCD23364.1 - 6.2e-06 26.4 0.1 0.037 14.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCD23364.1 - 0.0059 16.4 10.9 0.29 11.0 0.8 4.8 5 1 0 5 5 5 2 Tetratricopeptide repeat Sel1 PF08238.12 CCD23364.1 - 0.014 16.1 3.5 3.8 8.3 0.0 4.4 5 0 0 5 5 5 0 Sel1 repeat TPR_8 PF13181.6 CCD23364.1 - 0.18 12.1 15.3 0.31 11.4 0.5 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD23364.1 - 0.69 10.2 4.3 3.9 7.8 0.1 3.5 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Pkinase PF00069.25 CCD23365.1 - 3e-73 246.4 0.0 3.4e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23365.1 - 7e-32 110.7 0.0 1.9e-31 109.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CCD23365.1 - 0.00073 19.5 0.1 0.00099 19.1 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CCD23365.1 - 0.0023 17.3 0.1 0.0077 15.6 0.0 1.9 1 1 1 2 2 2 1 Kinase-like DUF676 PF05057.14 CCD23366.1 - 1.1e-53 182.0 0.2 1.9e-53 181.2 0.2 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 CCD23366.1 - 0.00077 18.7 0.1 0.21 10.7 0.0 2.3 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.7 CCD23366.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family SH3_9 PF14604.6 CCD23367.1 - 3.7e-05 23.5 0.1 7.5e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CCD23367.1 - 3.8e-05 23.2 0.1 0.00013 21.5 0.1 2.0 1 0 0 1 1 1 1 SH3 domain Transglut_core PF01841.19 CCD23367.1 - 0.00071 20.0 0.0 0.0018 18.7 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 CCD23367.1 - 0.0031 17.2 0.0 0.006 16.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Nup84_Nup100 PF04121.13 CCD23368.1 - 1.3e-186 621.9 15.1 1.6e-186 621.7 15.1 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 L_lactis_RepB_C PF06430.12 CCD23368.1 - 0.0056 16.7 1.1 0.015 15.3 0.2 2.2 2 0 0 2 2 2 1 Lactococcus lactis RepB C-terminus Iwr1 PF08574.10 CCD23369.1 - 3e-15 57.0 17.2 3e-15 57.0 17.2 3.4 3 1 0 3 3 3 1 Transcription factor Iwr1 adh_short PF00106.25 CCD23370.1 - 4.7e-40 137.2 0.0 6.4e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCD23370.1 - 7e-27 94.5 0.0 9.6e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCD23370.1 - 1.7e-11 44.3 0.1 1.8e-10 41.0 0.1 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CCD23370.1 - 1.2e-05 24.9 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCD23370.1 - 0.0037 16.3 0.1 0.0058 15.7 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CCD23370.1 - 0.24 10.4 0.0 0.38 9.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain PX PF00787.24 CCD23371.1 - 2.9e-25 88.4 0.2 1.1e-24 86.6 0.1 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 CCD23371.1 - 2.8e-06 27.1 7.8 0.00047 19.8 0.6 2.5 2 0 0 2 2 2 2 Vps5 C terminal like SpoU_methylase PF00588.19 CCD23372.1 - 1.8e-25 89.8 0.0 1.3e-24 87.0 0.0 2.4 2 0 0 2 2 2 1 SpoU rRNA Methylase family DUF3440 PF11922.8 CCD23372.1 - 0.14 11.8 0.4 0.52 10.0 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) CLAMP PF14769.6 CCD23372.1 - 6 7.4 7.2 4 8.0 0.1 3.9 4 0 0 4 4 4 0 Flagellar C1a complex subunit C1a-32 bZIP_2 PF07716.15 CCD23373.1 - 0.3 11.2 2.5 0.81 9.8 0.1 2.4 2 0 0 2 2 2 0 Basic region leucine zipper CSRNP_N PF16019.5 CCD23373.1 - 1.2 9.0 7.7 0.93 9.4 6.1 1.5 1 1 1 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DUF2951 PF11166.8 CCD23373.1 - 3.9 7.8 9.7 4.7 7.5 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) Mito_carr PF00153.27 CCD23374.1 - 6.8e-46 154.1 5.4 6.4e-17 61.3 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Frataxin_Cyay PF01491.16 CCD23375.1 - 3.9e-35 120.2 0.0 5.8e-35 119.6 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain DUF4834 PF16118.5 CCD23376.1 - 0.075 14.0 0.8 0.19 12.7 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) BCCT PF02028.17 CCD23376.1 - 0.23 9.8 0.0 0.29 9.5 0.0 1.0 1 0 0 1 1 1 0 BCCT, betaine/carnitine/choline family transporter UCH PF00443.29 CCD23377.1 - 9.9e-50 169.4 4.3 1.6e-49 168.8 4.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SSP160 PF06933.11 CCD23377.1 - 0.042 12.1 6.1 0.059 11.6 6.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SelK_SelG PF10961.8 CCD23377.1 - 0.13 12.9 0.3 0.9 10.2 0.1 2.4 2 0 0 2 2 2 0 Selenoprotein SelK_SelG DUF3439 PF11921.8 CCD23377.1 - 0.23 11.4 4.9 0.66 9.9 4.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) UCH_1 PF13423.6 CCD23377.1 - 0.99 8.9 28.0 9.5 5.7 28.0 2.6 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase RRM_1 PF00076.22 CCD23378.1 - 4.5e-55 183.4 1.9 1e-18 66.9 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCD23378.1 - 3.5e-10 39.6 0.0 0.00057 19.7 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CCD23378.1 - 1.8e-09 37.3 1.9 1.8e-05 24.3 0.5 2.8 2 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CCD23378.1 - 0.0011 18.9 0.2 0.075 13.0 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CCD23378.1 - 0.0011 19.0 0.1 0.25 11.5 0.0 3.8 3 1 1 4 4 4 1 RNA recognition motif DbpA PF03880.15 CCD23378.1 - 0.0059 16.6 0.1 0.79 9.8 0.0 2.6 2 0 0 2 2 2 1 DbpA RNA binding domain RNA_bind PF08675.11 CCD23378.1 - 0.044 13.8 0.1 2 8.5 0.0 3.0 3 0 0 3 3 3 0 RNA binding domain Robl_LC7 PF03259.17 CCD23378.1 - 0.075 12.8 0.8 0.15 11.9 0.8 1.4 1 0 0 1 1 1 0 Roadblock/LC7 domain Limkain-b1 PF11608.8 CCD23378.1 - 0.19 11.8 2.0 0.78 9.9 0.1 2.5 3 0 0 3 3 3 0 Limkain b1 DFP PF04127.15 CCD23379.1 - 7.4e-14 52.0 0.0 9.8e-06 25.5 0.0 3.1 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Sds3 PF08598.11 CCD23380.1 - 1.3e-74 250.9 7.0 1.6e-74 250.6 7.0 1.1 1 0 0 1 1 1 1 Sds3-like Glyco_transf_15 PF01793.16 CCD23381.1 - 9.8e-85 284.6 26.9 2.5e-56 191.3 14.5 2.2 1 1 1 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase CENP-T_C PF15511.6 CCD23382.1 - 1.8e-09 37.6 0.1 2.2e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CCD23382.1 - 1.4e-05 25.4 0.2 1.7e-05 25.2 0.2 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCD23382.1 - 1.9e-05 24.9 0.1 3.2e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CCD23382.1 - 2.5e-05 24.4 0.1 3.4e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CCD23382.1 - 0.00016 22.0 0.1 0.00022 21.6 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CCD23382.1 - 0.0028 17.7 0.0 0.0034 17.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CCD23382.1 - 0.0093 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 CCD23382.1 - 0.049 14.1 0.0 0.081 13.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 CCD23383.1 - 3.1e-49 166.7 3.4 3.4e-49 166.5 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CCD23383.1 - 2e-06 28.1 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CCD23383.1 - 5.5e-05 23.8 1.3 6.9e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CCD23383.1 - 0.00011 22.3 0.8 0.00015 21.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CCD23383.1 - 0.0018 18.5 0.9 0.0023 18.2 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CCD23383.1 - 0.035 14.2 0.2 0.058 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Aim19 PF10315.9 CCD23384.1 - 5e-39 133.2 1.9 6.2e-39 132.9 1.9 1.1 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Aa_trans PF01490.18 CCD23385.1 - 6.8e-113 377.5 22.1 8.7e-113 377.1 22.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ICE2 PF08426.10 CCD23386.1 - 3.7e-159 530.2 27.5 4.2e-159 530.0 27.5 1.0 1 0 0 1 1 1 1 ICE2 UTP25 PF06862.12 CCD23387.1 - 2.6e-203 676.1 9.3 3.5e-203 675.7 9.3 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 CCD23387.1 - 0.00011 22.0 0.2 0.48 10.2 0.1 2.7 3 0 0 3 3 3 2 DEAD/DEAH box helicase DUF2538 PF10804.8 CCD23387.1 - 0.02 14.6 0.3 0.058 13.2 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2538) MRP-S25 PF13741.6 CCD23388.1 - 5.5e-94 314.0 6.2 6.3e-94 313.8 6.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 CCD23388.1 - 2.6e-08 34.2 2.0 1.9e-06 28.1 0.1 2.8 1 1 1 3 3 3 2 Mitochondrial ribosomal protein S23 Iso_dh PF00180.20 CCD23389.1 - 4.9e-106 354.8 0.1 6e-106 354.5 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.25 CCD23390.1 - 3.8e-36 124.8 0.0 6.9e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23390.1 - 9.4e-26 90.6 0.0 1.4e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD23390.1 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCD23390.1 - 0.11 12.4 0.0 0.35 10.7 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2431 PF10354.9 CCD23391.1 - 4.3e-53 180.0 0.0 6.5e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) CLTH PF10607.9 CCD23392.1 - 2e-28 99.2 9.3 2e-28 99.2 9.3 3.0 3 2 0 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain Zn-C2H2_12 PF18112.1 CCD23392.1 - 0.067 13.7 0.4 0.22 12.0 0.4 1.8 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Iso_dh PF00180.20 CCD23393.1 - 1.2e-75 254.8 0.4 1.5e-75 254.5 0.4 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Complex1_LYR_2 PF13233.6 CCD23394.1 - 2.9e-12 47.2 11.2 3.7e-11 43.6 11.2 2.2 1 1 0 1 1 1 1 Complex1_LYR-like Diphthamide_syn PF01866.17 CCD23396.1 - 3.4e-115 384.7 0.0 4.5e-115 384.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SHQ1 PF04925.15 CCD23397.1 - 7.9e-68 227.5 0.8 1.2e-67 226.8 0.8 1.3 1 0 0 1 1 1 1 SHQ1 protein PH PF00169.29 CCD23398.1 - 5.7e-10 39.6 0.4 1.3e-09 38.5 0.4 1.6 1 0 0 1 1 1 1 PH domain RTT107_BRCT_5 PF16770.5 CCD23398.1 - 0.055 13.4 0.0 0.26 11.2 0.0 2.1 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Mob1_phocein PF03637.17 CCD23399.1 - 7.4e-68 227.8 0.0 1e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family 6PF2K PF01591.18 CCD23400.1 - 6.7e-84 280.6 0.2 1.3e-83 279.7 0.2 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CCD23400.1 - 2.2e-31 109.1 0.0 6.2e-26 91.3 0.0 3.2 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CCD23400.1 - 1.6e-05 25.1 0.2 5.6e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 CCD23400.1 - 0.0028 17.1 0.0 0.0081 15.6 0.0 1.8 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 CCD23400.1 - 0.0031 18.1 0.3 0.013 16.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CCD23400.1 - 0.004 17.6 0.0 0.017 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 CCD23400.1 - 0.0068 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase SlyX PF04102.12 CCD23400.1 - 0.009 16.6 0.1 0.033 14.8 0.1 2.0 1 0 0 1 1 1 1 SlyX Metallopep PF12044.8 CCD23401.1 - 1.5e-166 554.3 0.0 1.8e-166 554.0 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 CCD23401.1 - 0.0008 19.4 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_3 PF13582.6 CCD23401.1 - 0.029 14.9 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 CCD23401.1 - 0.37 9.7 1.6 0.41 9.5 0.3 1.6 2 0 0 2 2 2 0 Peptidase M66 Methyltransf_16 PF10294.9 CCD23402.1 - 0.063 13.0 0.1 5.5 6.7 0.1 2.6 3 0 0 3 3 3 0 Lysine methyltransferase DUF4898 PF16239.5 CCD23402.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4898) COX4 PF02936.14 CCD23403.1 - 6.9e-32 110.3 0.3 7.6e-32 110.2 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV B12D PF06522.11 CCD23403.1 - 0.0069 16.2 2.4 4.9 7.0 0.0 3.1 3 0 0 3 3 3 2 NADH-ubiquinone reductase complex 1 MLRQ subunit Ank_2 PF12796.7 CCD23404.1 - 3e-42 143.1 9.2 5.6e-18 65.3 0.8 4.2 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCD23404.1 - 3.2e-31 107.3 0.3 2.1e-09 37.8 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CCD23404.1 - 3.4e-28 97.3 2.2 1.5e-08 34.7 0.0 5.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCD23404.1 - 5.2e-27 90.9 0.4 5.1e-06 26.4 0.3 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 CCD23404.1 - 1.4e-25 88.6 3.7 3.9e-06 27.1 0.4 6.5 6 0 0 6 6 6 4 Ankyrin repeat Porin_3 PF01459.22 CCD23405.1 - 3.7e-68 229.9 0.4 4.1e-68 229.8 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin NUP214 PF16755.5 CCD23406.1 - 1.9e-124 415.5 9.4 1.9e-124 415.5 9.4 3.7 2 2 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 DUF929 PF06053.11 CCD23406.1 - 0.0011 18.4 0.1 0.003 16.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF929) WD40_like PF17005.5 CCD23406.1 - 0.0012 18.2 2.0 0.0029 17.0 2.0 1.6 1 0 0 1 1 1 1 WD40-like domain Nucleoporin_FG PF13634.6 CCD23406.1 - 0.12 13.2 110.6 0.081 13.8 16.9 5.9 2 1 4 6 6 6 0 Nucleoporin FG repeat region Chordopox_G2 PF05796.12 CCD23406.1 - 1.8 8.0 5.6 1.5 8.2 0.7 2.2 2 0 0 2 2 2 0 Chordopoxvirus protein G2 Aminotran_1_2 PF00155.21 CCD23407.1 - 6.1e-67 226.3 0.0 7.1e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 CCD23407.1 - 0.0064 15.4 0.0 0.0092 14.9 0.0 1.2 1 0 0 1 1 1 1 Allinase NAD_binding_3 PF03447.16 CCD23407.1 - 0.1 13.2 0.1 0.31 11.7 0.1 1.8 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain MIG-14_Wnt-bd PF06664.12 CCD23408.1 - 0.027 13.7 0.2 0.042 13.1 0.2 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Alpha_GJ PF03229.13 CCD23408.1 - 3.2 8.3 15.2 0.57 10.7 3.3 2.5 2 0 0 2 2 2 0 Alphavirus glycoprotein J Pex14_N PF04695.13 CCD23408.1 - 7.3 7.2 13.5 0.058 14.0 1.6 2.6 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ras PF00071.22 CCD23409.1 - 5.1e-57 192.0 0.2 7.5e-57 191.5 0.2 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD23409.1 - 1.8e-23 83.0 0.2 4.3e-23 81.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD23409.1 - 2.4e-09 36.9 0.1 4.7e-09 35.9 0.1 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CCD23409.1 - 8e-05 21.9 0.2 9.9e-05 21.6 0.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 CCD23409.1 - 0.0007 19.0 0.3 0.00095 18.6 0.3 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CCD23409.1 - 0.00072 19.0 0.0 0.0012 18.3 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CCD23409.1 - 0.0022 18.1 0.0 0.004 17.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 CCD23409.1 - 0.0045 17.2 0.0 0.29 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CCD23409.1 - 0.99 9.9 6.1 4.6 7.7 6.1 2.1 1 1 0 1 1 1 0 ABC transporter Myb_DNA-bind_4 PF13837.6 CCD23410.1 - 0.0044 17.4 0.5 0.011 16.1 0.1 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Noelin-1 PF12308.8 CCD23410.1 - 0.0067 16.4 0.1 0.02 14.9 0.1 1.7 1 0 0 1 1 1 1 Neurogenesis glycoprotein DUF4677 PF15726.5 CCD23410.1 - 0.43 10.7 2.4 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4677) Menin PF05053.13 CCD23410.1 - 1.2 7.4 8.3 1.9 6.8 8.3 1.3 1 0 0 1 1 1 0 Menin NOA36 PF06524.12 CCD23410.1 - 3.2 7.0 11.6 4.6 6.5 11.6 1.3 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.16 CCD23411.1 - 4.2e-41 141.1 28.6 1.2e-36 126.4 14.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily SUN PF03856.13 CCD23413.1 - 5.4e-98 327.3 12.5 5.4e-98 327.3 12.5 1.5 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) Macoilin PF09726.9 CCD23413.1 - 1.9 7.0 5.8 2.4 6.6 5.8 1.0 1 0 0 1 1 1 0 Macoilin family adh_short PF00106.25 CCD23414.1 - 4.4e-46 156.8 0.0 6.6e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCD23414.1 - 3.3e-26 92.3 0.0 4.1e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCD23414.1 - 9.2e-07 28.9 0.0 1.4e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CCD23414.1 - 2.8e-05 23.7 0.0 6.9e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CCD23414.1 - 0.0018 17.4 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.10 CCD23414.1 - 0.0021 17.5 0.1 0.023 14.0 0.1 2.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 CCD23414.1 - 0.057 13.7 0.0 0.13 12.6 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Transket_pyr PF02779.24 CCD23415.1 - 6e-65 218.2 0.0 1.1e-64 217.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 CCD23415.1 - 1.7e-56 191.4 0.0 2.4e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 CCD23415.1 - 9.4e-51 171.5 0.0 1.6e-50 170.8 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CCD23415.1 - 4.2e-19 67.8 0.9 4.2e-19 67.8 0.9 1.9 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus MULE PF10551.9 CCD23416.1 - 2.9e-09 37.2 0.1 6.5e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 CCD23416.1 - 0.0015 17.4 0.1 0.0035 16.2 0.1 1.5 1 0 0 1 1 1 1 Transposase, Mutator family UBA_e1_thiolCys PF10585.9 CCD23416.1 - 0.013 15.4 0.1 0.048 13.6 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Ribosomal_L6 PF00347.23 CCD23417.1 - 2.3e-29 101.9 12.3 4e-15 56.2 4.8 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 CPT_N PF16484.5 CCD23417.1 - 0.14 12.2 0.1 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Carnitine O-palmitoyltransferase N-terminus SNF2_N PF00176.23 CCD23418.1 - 3.3e-75 253.0 0.5 7.3e-75 251.9 0.5 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCD23418.1 - 1.4e-22 80.1 0.2 2e-19 70.0 0.0 3.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Bromodomain PF00439.25 CCD23418.1 - 2.5e-18 65.9 0.3 9.7e-18 64.0 0.3 2.1 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 CCD23418.1 - 1e-12 48.2 5.1 1e-12 48.2 5.1 3.0 3 0 0 3 3 3 1 HSA ResIII PF04851.15 CCD23418.1 - 1.4e-12 48.0 0.2 1.1e-11 45.0 0.0 2.7 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit SnAC PF14619.6 CCD23418.1 - 7.9e-09 36.0 0.0 7.9e-09 36.0 0.0 3.8 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex Fungal_trans PF04082.18 CCD23419.1 - 1.8e-40 138.7 0.5 4e-40 137.5 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD23419.1 - 1.4e-11 44.3 11.6 2.4e-11 43.5 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Forkhead PF00250.18 CCD23420.1 - 1.9e-27 95.3 1.4 2.2e-27 95.1 0.2 1.8 2 0 0 2 2 2 1 Forkhead domain FHA PF00498.26 CCD23420.1 - 5.6e-07 29.8 0.0 1.4e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 FHA domain Linker_histone PF00538.19 CCD23420.1 - 0.028 14.8 0.0 0.07 13.5 0.0 1.7 1 0 0 1 1 1 0 linker histone H1 and H5 family CSM2 PF16834.5 CCD23421.1 - 6.6e-72 241.4 4.0 7.5e-72 241.2 4.0 1.0 1 0 0 1 1 1 1 Shu complex component Csm2, DNA-binding Ribosomal_L13 PF00572.18 CCD23422.1 - 1.9e-11 44.3 0.1 1.7e-09 38.0 0.1 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 Mito_carr PF00153.27 CCD23423.1 - 1.9e-62 207.2 1.3 7.2e-24 83.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Lectin_N PF03954.14 CCD23425.1 - 0.015 15.1 3.1 0.58 9.9 0.2 2.8 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF883 PF05957.13 CCD23425.1 - 0.064 13.9 6.9 13 6.5 0.9 4.1 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 CCD23425.1 - 0.12 12.3 9.0 0.17 11.7 5.4 2.7 2 2 0 2 2 2 0 Apolipoprotein A1/A4/E domain YfdX PF10938.8 CCD23425.1 - 0.43 10.5 6.7 9.3 6.2 2.5 3.8 2 2 0 2 2 2 0 YfdX protein Exonuc_VII_L PF02601.15 CCD23425.1 - 2 7.9 17.9 1.8 8.1 7.3 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit DMPK_coil PF08826.10 CCD23425.1 - 2.5 8.3 7.5 0.56 10.4 0.4 2.9 2 1 0 2 2 2 0 DMPK coiled coil domain like DUF4398 PF14346.6 CCD23425.1 - 9.9 6.9 10.6 5.1 7.8 4.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4398) Peptidase_M1 PF01433.20 CCD23426.1 - 7.8e-35 120.4 8.5 2.3e-34 118.9 8.5 1.9 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CCD23426.1 - 1.4e-30 106.9 5.5 1.4e-30 106.9 5.5 2.3 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CCD23426.1 - 7.5e-12 45.4 0.5 1.5e-11 44.4 0.5 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Aminopep PF10023.9 CCD23426.1 - 0.021 14.2 0.2 0.021 14.2 0.2 1.8 2 0 0 2 2 2 0 Putative aminopeptidase Tropomyosin_1 PF12718.7 CCD23427.1 - 1.2e-50 171.4 44.9 1.4e-50 171.2 44.9 1.0 1 0 0 1 1 1 1 Tropomyosin like KLRAQ PF10205.9 CCD23427.1 - 1.5e-06 28.4 30.6 0.00059 20.0 16.3 2.1 1 1 1 2 2 2 2 Predicted coiled-coil domain-containing protein Tropomyosin PF00261.20 CCD23427.1 - 3.9e-05 23.1 41.1 0.0093 15.4 16.9 2.2 1 1 1 2 2 2 2 Tropomyosin Laminin_II PF06009.12 CCD23427.1 - 0.00087 19.3 24.5 0.004 17.2 12.5 2.2 1 1 1 2 2 2 1 Laminin Domain II CENP-F_leu_zip PF10473.9 CCD23427.1 - 0.0012 18.9 9.5 0.0012 18.9 9.5 2.6 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 CCD23427.1 - 0.0022 18.2 36.5 0.063 13.5 14.8 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) GAS PF13851.6 CCD23427.1 - 0.0026 17.1 40.1 2.9 7.2 39.9 2.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding MbeD_MobD PF04899.12 CCD23427.1 - 0.0036 17.4 2.3 0.0036 17.4 2.3 2.8 2 1 1 3 3 3 1 MbeD/MobD like Fez1 PF06818.15 CCD23427.1 - 0.0051 17.3 31.1 0.0067 16.9 31.1 1.2 1 0 0 1 1 1 1 Fez1 Spc7 PF08317.11 CCD23427.1 - 0.0055 15.6 40.1 0.023 13.6 16.6 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein Taxilin PF09728.9 CCD23427.1 - 0.007 15.6 14.4 0.007 15.6 14.4 2.7 1 1 1 2 2 2 1 Myosin-like coiled-coil protein CENP-K PF11802.8 CCD23427.1 - 0.0073 15.9 9.1 0.0073 15.9 9.1 2.0 1 1 1 2 2 2 1 Centromere-associated protein K BLOC1_2 PF10046.9 CCD23427.1 - 0.0078 16.5 30.2 0.12 12.7 10.4 3.7 1 1 2 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.15 CCD23427.1 - 0.01 15.6 9.6 0.01 15.6 9.6 4.6 1 1 2 4 4 4 0 Septum formation initiator APG6_N PF17675.1 CCD23427.1 - 0.012 16.2 49.8 0.36 11.3 22.6 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region bZIP_2 PF07716.15 CCD23427.1 - 0.013 15.6 5.8 0.013 15.6 5.8 4.9 2 2 3 5 5 4 0 Basic region leucine zipper Glyco_hydro_44 PF12891.7 CCD23427.1 - 0.023 14.6 4.3 0.029 14.3 4.3 1.2 1 0 0 1 1 1 0 Glycoside hydrolase family 44 WXG100 PF06013.12 CCD23427.1 - 0.066 13.4 14.6 0.43 10.8 0.2 3.9 2 1 0 3 3 3 0 Proteins of 100 residues with WXG FlaC_arch PF05377.11 CCD23427.1 - 0.079 13.4 31.1 0.72 10.3 2.8 4.6 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) ERM PF00769.19 CCD23427.1 - 0.086 12.6 40.3 0.86 9.4 40.3 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family CLZ PF16526.5 CCD23427.1 - 0.097 13.0 30.0 1.9 8.9 3.1 3.9 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 CCD23427.1 - 0.12 12.9 14.8 8.4 6.9 0.1 3.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 CCD23427.1 - 0.12 10.5 32.4 0.27 9.4 30.8 1.9 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3450 PF11932.8 CCD23427.1 - 0.12 11.6 31.6 0.18 11.1 13.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Sec34 PF04136.15 CCD23427.1 - 0.13 12.1 24.1 0.76 9.6 13.0 2.1 1 1 1 2 2 2 0 Sec34-like family Uso1_p115_C PF04871.13 CCD23427.1 - 0.15 12.4 42.3 1 9.8 18.3 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ZapB PF06005.12 CCD23427.1 - 0.21 12.1 47.8 2.9 8.4 19.7 4.0 2 1 1 3 3 3 0 Cell division protein ZapB DUF3584 PF12128.8 CCD23427.1 - 0.23 8.9 31.8 0.26 8.7 31.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 CCD23427.1 - 0.24 11.4 19.8 1.1 9.4 6.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4201 PF13870.6 CCD23427.1 - 0.27 11.0 33.4 2.8 7.6 33.4 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF724 PF05266.14 CCD23427.1 - 0.3 10.9 32.1 1.3 8.8 11.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 CCD23427.1 - 0.37 10.1 20.7 0.5 9.7 20.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 CCD23427.1 - 0.42 10.7 33.7 0.15 12.1 13.3 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 CCD23427.1 - 0.47 10.5 48.7 0.082 12.9 20.9 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Rho_Binding PF08912.11 CCD23427.1 - 0.54 11.1 47.4 0.13 13.1 10.2 4.0 1 1 3 4 4 4 0 Rho Binding TPR_MLP1_2 PF07926.12 CCD23427.1 - 0.58 10.2 44.7 2.3 8.3 9.3 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.20 CCD23427.1 - 0.58 10.1 42.5 0.67 9.9 17.7 3.2 1 1 2 3 3 3 0 Prefoldin subunit Lectin_N PF03954.14 CCD23427.1 - 0.59 9.9 17.3 9.7 5.9 3.2 2.9 1 1 3 4 4 4 0 Hepatic lectin, N-terminal domain Atg14 PF10186.9 CCD23427.1 - 0.94 8.5 30.3 0.32 10.1 11.0 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_1 PF00170.21 CCD23427.1 - 1 9.5 40.6 4.3 7.5 0.6 4.6 1 1 3 4 4 4 0 bZIP transcription factor OmpH PF03938.14 CCD23427.1 - 1 9.7 38.9 0.21 11.9 15.6 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) HisKA_3 PF07730.13 CCD23427.1 - 1 9.9 7.2 8.1 7.0 0.3 3.7 2 1 1 3 3 3 0 Histidine kinase Sec2p PF06428.11 CCD23427.1 - 1.2 9.1 37.3 7.2 6.7 1.5 3.7 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Fzo_mitofusin PF04799.13 CCD23427.1 - 1.4 8.5 22.2 2.2 7.8 2.5 2.7 1 1 1 2 2 2 0 fzo-like conserved region Mod_r PF07200.13 CCD23427.1 - 1.4 9.0 39.1 18 5.4 15.8 3.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF745 PF05335.13 CCD23427.1 - 1.7 8.3 22.6 2.7 7.7 8.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Seryl_tRNA_N PF02403.22 CCD23427.1 - 2 8.7 36.5 3.2 8.0 2.4 3.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4107 PF13389.6 CCD23427.1 - 2.1 8.5 6.3 2.5 8.2 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) DUF4200 PF13863.6 CCD23427.1 - 2.5 8.5 44.1 1.6 9.1 18.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DHR10 PF18595.1 CCD23427.1 - 2.5 8.2 39.6 0.93 9.6 16.3 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Spc24 PF08286.11 CCD23427.1 - 2.5 8.4 39.4 1.1 9.5 5.6 4.0 1 1 3 4 4 4 0 Spc24 subunit of Ndc80 PRKG1_interact PF15898.5 CCD23427.1 - 2.7 8.9 37.3 1.3 10.0 18.9 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain FAM184 PF15665.5 CCD23427.1 - 3 7.6 34.9 10 5.9 24.9 2.1 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B IFT57 PF10498.9 CCD23427.1 - 3 6.7 30.8 1.2 8.1 18.9 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Ax_dynein_light PF10211.9 CCD23427.1 - 3.1 7.7 40.8 0.61 10.0 13.5 3.1 1 1 2 3 3 3 0 Axonemal dynein light chain DUF3552 PF12072.8 CCD23427.1 - 3.1 7.2 38.7 3.7 6.9 4.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) CENP-H PF05837.12 CCD23427.1 - 3.1 8.2 31.5 3.5 8.1 12.6 2.9 1 1 1 2 2 1 0 Centromere protein H (CENP-H) HMMR_C PF15908.5 CCD23427.1 - 3.5 7.9 28.3 1.2 9.3 2.5 2.8 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal PI3K_P85_iSH2 PF16454.5 CCD23427.1 - 4.1 7.0 32.7 2.6 7.6 27.8 2.0 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain YtxH PF12732.7 CCD23427.1 - 4.1 8.0 19.0 1.8e+04 -6.2 19.0 3.3 1 1 0 1 1 0 0 YtxH-like protein LPP PF04728.13 CCD23427.1 - 4.3 7.8 15.0 0.86 10.0 0.8 3.9 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Lebercilin PF15619.6 CCD23427.1 - 4.3 6.9 37.9 29 4.2 37.9 2.0 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease KASH_CCD PF14662.6 CCD23427.1 - 4.9 6.9 42.3 5.2 6.9 21.9 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Occludin_ELL PF07303.13 CCD23427.1 - 6 7.7 23.3 1.9e+03 -0.4 0.0 3.2 1 1 1 2 2 1 0 Occludin homology domain Spectrin PF00435.21 CCD23427.1 - 6.6 7.3 32.1 4.7 7.8 13.1 3.1 1 1 2 3 3 3 0 Spectrin repeat KELK PF15796.5 CCD23427.1 - 6.8 7.2 39.3 0.18 12.2 2.7 3.9 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SOGA PF11365.8 CCD23427.1 - 7.3 7.8 27.4 13 6.9 23.2 2.8 1 1 1 2 2 2 0 Protein SOGA Med30 PF11315.8 CCD23427.1 - 8 6.6 25.4 7.3 6.8 9.6 2.9 1 1 1 2 2 2 0 Mediator complex subunit 30 Cnn_1N PF07989.11 CCD23427.1 - 9.2 6.5 39.9 7.3 6.8 17.9 3.5 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 FapA PF03961.13 CCD23427.1 - 9.5 4.7 34.8 3.8 6.0 16.7 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A HORMA PF02301.18 CCD23428.1 - 1.4e-15 57.5 2.0 1.8e-15 57.1 2.0 1.2 1 0 0 1 1 1 1 HORMA domain T6PP_N PF18572.1 CCD23428.1 - 0.075 12.9 0.4 0.14 12.0 0.4 1.5 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Gallidermin PF02052.15 CCD23428.1 - 2.2 8.7 4.3 28 5.2 0.0 3.3 2 1 1 3 3 3 0 Gallidermin SKG6 PF08693.10 CCD23429.1 - 1.8e-16 59.2 1.6 1.8e-16 59.2 1.6 3.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain He_PIG PF05345.12 CCD23429.1 - 1.9e-10 40.7 16.6 3.9e-06 27.0 0.2 5.3 5 0 0 5 5 5 2 Putative Ig domain RIFIN PF02009.16 CCD23429.1 - 2.4e-06 27.7 0.7 4.6e-06 26.8 0.7 1.4 1 0 0 1 1 1 1 Rifin DUF1180 PF06679.12 CCD23429.1 - 8.9e-06 26.2 0.9 2.5e-05 24.8 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Stevor PF17410.2 CCD23429.1 - 0.00098 18.8 1.9 0.00098 18.8 1.9 1.8 2 0 0 2 2 2 1 Subtelomeric Variable Open Reading frame Adeno_E3_CR2 PF02439.15 CCD23429.1 - 0.0016 18.2 0.2 0.0032 17.2 0.2 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Cytomega_TRL10 PF06084.11 CCD23429.1 - 0.027 14.5 2.0 0.083 12.9 2.0 1.8 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein EphA2_TM PF14575.6 CCD23429.1 - 0.029 15.2 0.0 0.16 12.9 0.0 2.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_M56 PF05569.11 CCD23429.1 - 0.036 13.2 0.7 0.097 11.8 0.7 1.7 1 0 0 1 1 1 0 BlaR1 peptidase M56 BPS1 PF05633.11 CCD23429.1 - 0.055 12.5 9.3 0.088 11.8 9.3 1.2 1 0 0 1 1 1 0 Protein BYPASS1-related GT87 PF09594.10 CCD23429.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 87 DUF5385 PF17359.2 CCD23429.1 - 0.14 11.7 0.2 0.26 10.8 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF2615 PF11027.8 CCD23429.1 - 0.37 10.9 0.0 0.37 10.9 0.0 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF2615) DUF5305 PF17231.2 CCD23429.1 - 1.5 8.1 8.4 0.51 9.7 4.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5305) EF-hand_4 PF12763.7 CCD23430.1 - 3.3e-51 171.6 4.4 2.3e-49 165.6 2.3 2.6 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand End3 PF12761.7 CCD23430.1 - 2e-33 116.3 9.9 2.5e-30 106.2 9.9 2.2 1 1 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.32 CCD23430.1 - 0.0083 15.6 2.0 0.022 14.3 2.0 1.8 1 0 0 1 1 1 1 EF hand CC2-LZ PF16516.5 CCD23430.1 - 0.031 14.6 3.4 0.17 12.3 0.5 2.6 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Prefoldin_2 PF01920.20 CCD23430.1 - 0.098 12.6 9.0 0.78 9.7 2.8 2.7 2 0 0 2 2 2 0 Prefoldin subunit Cadherin_tail PF15974.5 CCD23430.1 - 0.1 12.9 0.8 0.95 9.8 0.0 2.2 2 0 0 2 2 2 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region PI3K_P85_iSH2 PF16454.5 CCD23430.1 - 0.14 11.7 5.5 0.065 12.8 1.7 2.2 1 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF641 PF04859.12 CCD23430.1 - 0.19 12.0 4.2 1.1 9.6 0.8 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) GAS PF13851.6 CCD23430.1 - 0.2 11.0 7.4 1.4 8.2 0.4 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding XhlA PF10779.9 CCD23430.1 - 0.3 11.3 6.3 2.7 8.3 1.7 2.5 2 0 0 2 2 2 0 Haemolysin XhlA ADIP PF11559.8 CCD23430.1 - 0.69 10.0 7.6 4.7 7.3 0.6 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.11 CCD23430.1 - 0.72 10.1 7.5 1.4 9.2 1.4 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Cep57_CLD_2 PF14197.6 CCD23430.1 - 0.88 9.7 6.8 2 8.6 0.2 2.7 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Csm1_N PF18504.1 CCD23430.1 - 1.4 9.3 9.5 5 7.5 0.3 3.0 3 0 0 3 3 3 0 Csm1 N-terminal domain Tropomyosin_1 PF12718.7 CCD23430.1 - 1.5 9.0 10.6 1.8 8.7 1.3 3.0 3 0 0 3 3 3 0 Tropomyosin like Fib_alpha PF08702.10 CCD23430.1 - 1.7 8.8 9.1 11 6.2 9.1 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Prefoldin PF02996.17 CCD23430.1 - 2.4 8.1 7.8 0.52 10.2 2.8 2.3 2 1 0 2 2 2 0 Prefoldin subunit DUF2408 PF10303.9 CCD23430.1 - 3.3 8.3 7.2 12 6.4 1.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) DUF4140 PF13600.6 CCD23430.1 - 5.7 7.4 8.3 8.7 6.9 1.4 2.4 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 CCD23430.1 - 9.9 6.6 8.4 12 6.4 1.4 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Cpn60_TCP1 PF00118.24 CCD23431.1 - 1.6e-147 492.1 10.5 1.8e-147 491.9 10.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 CCD23431.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Helicase_C PF00271.31 CCD23433.1 - 1e-15 58.1 0.0 2.1e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCD23433.1 - 3.6e-05 23.6 0.0 9.4e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HAP2-GCS1 PF10699.9 CCD23433.1 - 0.026 14.5 0.2 0.068 13.2 0.2 1.7 1 0 0 1 1 1 0 Male gamete fusion factor AAA_22 PF13401.6 CCD23433.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain MKT1_C PF12246.8 CCD23435.1 - 2.7e-58 197.1 3.7 7.4e-58 195.6 3.6 1.9 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 CCD23435.1 - 3.8e-27 94.5 0.1 3.6e-26 91.3 0.0 2.8 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 CCD23435.1 - 7.3e-20 71.3 0.0 2e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain Hormone_3 PF00159.18 CCD23435.1 - 0.0084 16.2 1.1 0.16 12.0 0.1 3.0 2 0 0 2 2 2 1 Pancreatic hormone peptide XPG_I PF00867.18 CCD23435.1 - 0.02 15.2 0.1 0.091 13.1 0.1 2.2 1 1 0 1 1 1 0 XPG I-region OST3_OST6 PF04756.13 CCD23436.1 - 2.4e-78 263.5 1.3 2.7e-78 263.3 1.3 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Transmemb_17 PF09799.9 CCD23436.1 - 0.51 10.9 7.1 0.35 11.5 0.7 2.6 2 0 0 2 2 2 0 Predicted membrane protein C2 PF00168.30 CCD23437.1 - 2.1e-59 198.2 8.1 7.9e-18 64.7 0.0 4.6 4 0 0 4 4 4 4 C2 domain SMP_LBD PF17047.5 CCD23437.1 - 0.0018 17.8 0.0 0.0047 16.4 0.0 1.7 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain Ion_trans PF00520.31 CCD23438.1 - 0.00013 21.3 20.8 0.00032 20.0 20.8 1.7 1 0 0 1 1 1 1 Ion transport protein DUF2645 PF10840.8 CCD23438.1 - 0.074 13.7 0.3 0.074 13.7 0.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2645) Syntaxin-6_N PF09177.11 CCD23438.1 - 0.26 11.9 3.2 0.6 10.7 3.2 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Ras PF00071.22 CCD23439.1 - 1.5e-28 99.4 0.2 1.9e-28 99.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD23439.1 - 2.4e-08 34.2 0.1 3.6e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD23439.1 - 3.1e-05 23.5 0.2 3.7e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CCD23439.1 - 0.11 12.4 0.1 0.15 12.0 0.1 1.1 1 0 0 1 1 1 0 RsgA GTPase PP2C PF00481.21 CCD23440.1 - 4.2e-51 174.1 0.0 9.3e-51 172.9 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C UBA_e1_thiolCys PF10585.9 CCD23441.1 - 0.00097 19.1 0.0 0.0011 19.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Clathrin_H_link PF13838.6 CCD23441.1 - 0.014 15.3 0.2 0.035 14.0 0.0 1.6 2 0 0 2 2 2 0 Clathrin-H-link MgrB PF13998.6 CCD23441.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 MgrB protein Mem_trans PF03547.18 CCD23443.1 - 1.1e-32 112.9 0.0 4e-32 111.1 0.0 1.8 1 1 0 1 1 1 1 Membrane transport protein AMP-binding PF00501.28 CCD23444.1 - 5.5e-36 124.1 0.0 1.2e-12 47.2 0.0 5.1 5 0 0 5 5 5 5 AMP-binding enzyme DMAP_binding PF06464.11 CCD23444.1 - 3.8e-14 53.4 2.1 3.8e-14 53.4 2.1 3.2 4 0 0 4 4 4 1 DMAP1-binding Domain OHA PF14418.6 CCD23444.1 - 0.052 13.4 0.2 0.24 11.3 0.2 2.1 1 0 0 1 1 1 0 OST-HTH Associated domain Arf PF00025.21 CCD23445.1 - 2.5e-71 238.7 0.5 2.9e-71 238.5 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CCD23445.1 - 1.3e-16 60.6 0.0 1.6e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CCD23445.1 - 2.7e-15 56.6 0.1 3.9e-15 56.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CCD23445.1 - 3.3e-13 49.5 1.7 9.9e-09 34.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CCD23445.1 - 6.6e-13 48.6 0.0 7.4e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CCD23445.1 - 4.2e-10 39.4 0.0 5.3e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCD23445.1 - 5.2e-06 26.5 0.1 7.9e-06 25.9 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CCD23445.1 - 0.029 13.7 0.2 0.061 12.6 0.2 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_14 PF13173.6 CCD23445.1 - 0.4 10.7 1.7 3.4 7.7 0.1 2.2 1 1 1 2 2 2 0 AAA domain Rib_5-P_isom_A PF06026.14 CCD23446.1 - 1e-60 204.3 0.0 1.3e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 CCD23446.1 - 0.03 14.2 0.0 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Ribosomal_S7e PF01251.18 CCD23447.1 - 1.4e-21 77.1 0.2 1.5e-21 77.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Nucleoporin_FG PF13634.6 CCD23449.1 - 3.4e-05 24.6 21.5 3.4e-05 24.6 21.5 10.2 2 2 7 9 9 9 3 Nucleoporin FG repeat region Glyco_transf_15 PF01793.16 CCD23450.1 - 2.7e-130 434.4 11.5 3.3e-130 434.1 11.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Mito_carr PF00153.27 CCD23451.1 - 2.1e-55 184.7 4.9 4e-20 71.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 CCD23452.1 - 4.3e-57 192.2 0.7 7.6e-57 191.4 0.7 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD23452.1 - 9.5e-21 74.2 0.1 9.5e-21 74.2 0.1 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD23452.1 - 2e-09 37.2 0.6 7.4e-09 35.3 0.1 2.0 1 1 1 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CCD23452.1 - 0.0015 18.1 5.3 0.0026 17.3 3.6 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CCD23452.1 - 0.0023 18.0 0.0 0.0023 18.0 0.0 2.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCD23452.1 - 0.0042 17.0 7.7 0.3 11.0 0.1 3.5 2 1 2 4 4 4 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CCD23452.1 - 0.032 14.2 1.0 0.15 12.1 0.1 2.4 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain GAGA_bind PF06217.12 CCD23452.1 - 0.23 11.7 9.7 0.36 11.1 9.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 CCD23452.1 - 3.8 7.3 15.7 6.2 6.6 15.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Macoilin PF09726.9 CCD23452.1 - 4.5 5.7 12.8 5.3 5.5 12.8 1.2 1 0 0 1 1 1 0 Macoilin family SNARE PF05739.19 CCD23454.1 - 8.6e-15 54.5 2.1 8.6e-15 54.5 2.1 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 CCD23454.1 - 1.3e-05 25.5 0.8 1.3e-05 25.5 0.8 3.5 2 2 1 3 3 3 2 Syntaxin-like protein Synaptobrevin PF00957.21 CCD23454.1 - 0.0001 22.0 1.8 0.0001 22.0 1.8 2.0 2 0 0 2 2 2 1 Synaptobrevin TMPIT PF07851.13 CCD23454.1 - 0.00071 18.9 3.9 0.00071 18.9 3.9 1.7 2 0 0 2 2 2 1 TMPIT-like protein Myosin_tail_1 PF01576.19 CCD23454.1 - 0.0022 15.9 14.9 0.0051 14.7 11.6 2.0 2 0 0 2 2 2 1 Myosin tail Occludin_ELL PF07303.13 CCD23454.1 - 0.0077 16.9 0.5 0.0077 16.9 0.5 3.2 1 1 2 3 3 2 1 Occludin homology domain Rx_N PF18052.1 CCD23454.1 - 0.027 14.8 0.2 0.027 14.8 0.2 2.6 4 0 0 4 4 4 0 Rx N-terminal domain S6PP_C PF08472.10 CCD23454.1 - 0.076 12.9 0.4 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal DUF5345 PF17280.2 CCD23454.1 - 0.083 12.9 0.1 0.083 12.9 0.1 3.2 3 1 0 3 3 2 0 Family of unknown function (DUF5345) Use1 PF09753.9 CCD23454.1 - 0.085 12.6 17.9 1.2 8.8 17.9 2.5 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF5383 PF17355.2 CCD23454.1 - 0.12 12.7 0.2 0.12 12.7 0.2 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5383) COG5 PF10392.9 CCD23454.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Seryl_tRNA_N PF02403.22 CCD23454.1 - 0.38 11.0 16.7 0.14 12.4 11.3 2.6 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain ISG65-75 PF11727.8 CCD23454.1 - 0.53 9.5 5.6 0.43 9.8 1.4 2.3 2 1 0 2 2 2 0 Invariant surface glycoprotein Consortin_C PF15281.6 CCD23454.1 - 0.81 9.7 6.9 0.46 10.5 0.3 2.4 2 0 0 2 2 2 0 Consortin C-terminus EIIBC-GUT_N PF03612.14 CCD23454.1 - 0.87 9.3 8.9 0.17 11.6 4.3 1.9 1 1 1 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Syntaxin PF00804.25 CCD23454.1 - 0.88 9.2 16.6 0.13 12.0 7.9 3.0 3 0 0 3 3 3 0 Syntaxin Phage_GPO PF05929.11 CCD23454.1 - 2.5 7.7 15.5 20 4.7 12.9 2.4 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase MCU PF04678.13 CCD23454.1 - 2.7 8.1 13.1 28 4.7 13.1 2.5 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Spc7 PF08317.11 CCD23454.1 - 3.9 6.3 19.0 1.5 7.7 13.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Spectrin PF00435.21 CCD23454.1 - 4.6 7.8 18.7 1.6 9.3 10.7 3.2 3 1 1 4 4 4 0 Spectrin repeat bZIP_2 PF07716.15 CCD23455.1 - 0.025 14.6 3.7 0.085 12.9 3.7 2.0 1 0 0 1 1 1 0 Basic region leucine zipper RGS PF00615.19 CCD23456.1 - 2.2e-07 31.1 3.2 7.6e-07 29.4 3.2 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain RE_Bpu10I PF09549.10 CCD23456.1 - 0.25 10.9 1.6 0.72 9.4 0.2 2.3 3 1 0 3 3 3 0 Bpu10I restriction endonuclease HMGL-like PF00682.19 CCD23457.1 - 5.6e-91 304.7 0.0 7.9e-91 304.3 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 CCD23457.1 - 1.9e-28 99.0 0.6 3.7e-28 98.1 0.6 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Syja_N PF02383.18 CCD23458.1 - 5.5e-76 255.9 0.7 1.1e-75 254.9 0.7 1.5 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 CCD23458.1 - 3.2e-14 53.0 0.0 5.5e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YEATS PF03366.16 CCD23459.1 - 5.5e-36 122.4 0.8 9.9e-36 121.6 0.8 1.4 1 0 0 1 1 1 1 YEATS family His_Phos_1 PF00300.22 CCD23460.1 - 4.9e-16 59.0 0.0 7.7e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TFIIIC_sub6 PF10419.9 CCD23460.1 - 9.6e-15 54.2 0.0 2e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Maf PF02545.14 CCD23461.1 - 9.3e-34 116.7 0.0 1.2e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein ROK PF00480.20 CCD23461.1 - 0.18 11.3 0.1 0.25 10.8 0.1 1.2 1 0 0 1 1 1 0 ROK family HEAT PF02985.22 CCD23462.1 - 0.0097 16.1 0.4 8.2 7.0 0.0 4.7 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 CCD23462.1 - 0.027 14.5 2.9 2.7 8.0 0.2 2.9 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF4023 PF13215.6 CCD23462.1 - 0.11 12.6 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) zf-H2C2_2 PF13465.6 CCD23463.1 - 5e-20 71.0 31.1 2e-08 34.3 0.9 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 CCD23463.1 - 9.1e-18 63.7 38.5 2.2e-05 24.6 0.5 6.0 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD23463.1 - 1.9e-10 40.7 30.0 0.0032 18.2 0.4 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCD23463.1 - 2.9e-06 27.1 28.3 0.015 15.2 0.2 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCD23463.1 - 0.002 18.4 14.2 0.1 12.9 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCD23463.1 - 0.0042 17.4 0.1 0.0042 17.4 0.1 5.4 6 0 0 6 6 5 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CCD23463.1 - 0.0057 16.9 5.7 0.081 13.2 0.3 2.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding SpoIISB_antitox PF14185.6 CCD23463.1 - 0.016 15.1 0.2 0.067 13.1 0.2 2.1 1 0 0 1 1 1 0 Antitoxin SpoIISB, type II toxin-antitoxin system C1_4 PF07975.12 CCD23463.1 - 0.29 11.4 2.5 3.2 8.1 0.6 3.0 2 0 0 2 2 2 0 TFIIH C1-like domain PyrI_C PF02748.15 CCD23463.1 - 1.4 8.8 5.3 66 3.5 0.2 3.6 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.10 CCD23463.1 - 4.1 7.6 10.5 1.7 8.9 2.6 3.6 3 1 1 4 4 4 0 Zinc ribbon domain zf-CHCC PF10276.9 CCD23463.1 - 5.6 7.1 10.6 3.7 7.7 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger domain DUF3589 PF12141.8 CCD23464.1 - 3.5e-81 273.3 0.4 3.8e-56 190.7 0.0 2.6 1 1 1 2 2 2 2 Beta-mannosyltransferases TRAPP PF04051.16 CCD23465.1 - 4e-31 107.7 0.0 5.9e-31 107.2 0.0 1.3 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component NBD94 PF16830.5 CCD23465.1 - 0.059 13.8 0.6 0.059 13.8 0.6 2.4 2 1 1 3 3 3 0 Nucleotide-Binding Domain 94 of RH SH3_9 PF14604.6 CCD23466.1 - 6.1e-26 90.0 0.1 2.8e-13 49.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CCD23466.1 - 2.3e-23 81.5 0.0 9.2e-11 41.2 0.0 2.7 2 0 0 2 2 2 2 SH3 domain FCH PF00611.23 CCD23466.1 - 1.1e-18 67.3 3.1 1.7e-18 66.7 0.5 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 CCD23466.1 - 1.1e-13 50.7 0.0 4.3e-08 32.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 CCD23466.1 - 0.057 13.7 0.5 0.86 9.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain SH3_10 PF17902.1 CCD23466.1 - 0.066 13.3 0.1 9.2 6.4 0.0 2.8 3 0 0 3 3 3 0 SH3 domain CHCH PF06747.13 CCD23467.1 - 7.8e-07 29.1 10.0 1.4e-06 28.3 10.0 1.5 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 CCD23467.1 - 3.1e-05 24.1 2.4 4.9e-05 23.5 2.4 1.3 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 CCD23467.1 - 0.026 14.8 4.7 0.042 14.1 4.7 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Podoplanin PF05808.11 CCD23467.1 - 0.31 11.1 2.7 0.35 11.0 2.7 1.1 1 0 0 1 1 1 0 Podoplanin TPR_1 PF00515.28 CCD23468.1 - 2.8e-21 74.4 31.7 3.2e-06 26.7 2.5 9.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 CCD23468.1 - 1e-17 62.7 34.2 0.00028 20.8 1.2 10.7 10 1 1 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.6 CCD23468.1 - 3.9e-16 57.8 23.1 0.014 15.6 0.5 9.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 CCD23468.1 - 4.7e-14 52.7 1.4 0.44 11.2 0.0 5.6 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 CCD23468.1 - 1.3e-12 47.2 22.4 0.00048 19.8 0.2 6.9 6 1 1 7 7 7 4 TPR repeat TPR_19 PF14559.6 CCD23468.1 - 8.5e-12 45.4 16.3 0.035 14.6 1.8 5.9 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 CCD23468.1 - 8.6e-09 35.2 20.0 0.001 19.3 0.1 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCD23468.1 - 3.1e-08 33.8 9.9 0.15 13.0 0.1 7.5 5 3 3 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCD23468.1 - 1.3e-07 31.8 15.3 0.27 11.6 0.1 6.5 5 2 1 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD23468.1 - 3.3e-05 24.0 18.0 0.061 13.5 0.4 5.1 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CCD23468.1 - 0.00011 21.9 10.9 0.21 11.7 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 CCD23468.1 - 0.00042 20.4 0.8 0.59 10.3 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CCD23468.1 - 0.00081 19.0 0.0 0.7 9.5 0.2 3.4 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_MalT PF17874.1 CCD23468.1 - 0.014 14.8 3.0 0.26 10.6 1.6 3.1 2 1 1 3 3 3 0 MalT-like TPR region NARP1 PF12569.8 CCD23468.1 - 0.029 13.3 0.1 0.029 13.3 0.1 4.7 2 2 2 5 5 5 0 NMDA receptor-regulated protein 1 SARAF PF06682.12 CCD23468.1 - 0.035 13.8 1.0 0.061 13.0 1.0 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Exonuc_VII_S PF02609.16 CCD23468.1 - 0.31 11.1 2.9 1.3 9.1 0.1 3.5 4 0 0 4 4 3 0 Exonuclease VII small subunit TPR_21 PF09976.9 CCD23468.1 - 0.33 10.6 12.5 3.4 7.3 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat-like domain SR-25 PF10500.9 CCD23468.1 - 1.2 8.7 14.6 1.9 8.0 14.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_20 PF14561.6 CCD23468.1 - 2.9 8.3 8.4 2.5 8.5 1.1 3.6 3 1 0 3 3 2 0 Tetratricopeptide repeat SpoIIIAH PF12685.7 CCD23468.1 - 4.2 7.1 13.5 0.6 9.9 8.7 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein ORC6 PF05460.13 CCD23469.1 - 3.2e-92 309.6 1.9 4.2e-92 309.2 1.9 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Ndc1_Nup PF09531.10 CCD23469.1 - 0.38 9.4 1.2 0.49 9.0 1.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC45 PF02724.14 CCD23469.1 - 4.3 5.5 7.5 6.1 5.0 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein N-SET PF11764.8 CCD23470.1 - 1.8e-48 164.9 2.1 1.8e-48 164.9 2.1 2.3 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 CCD23470.1 - 2.4e-20 71.9 0.5 6.3e-20 70.6 0.5 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 CCD23470.1 - 2.5e-18 67.0 0.1 2.5e-18 67.0 0.1 3.0 3 2 0 3 3 3 1 SET domain Troponin PF00992.20 CCD23470.1 - 0.87 9.9 11.6 0.13 12.6 6.5 2.3 2 0 0 2 2 2 0 Troponin MutS_V PF00488.21 CCD23471.1 - 9.7e-66 221.4 0.0 2e-65 220.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CCD23471.1 - 1.3e-32 113.6 2.1 4.9e-32 111.7 2.4 1.9 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 CCD23471.1 - 2.6e-25 88.8 0.0 1.1e-24 86.8 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 CCD23471.1 - 1.3e-08 35.3 0.2 6.4e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 MutS domain II VEG PF06257.11 CCD23471.1 - 0.045 13.8 0.1 3.1 7.9 0.0 2.8 2 0 0 2 2 2 0 Biofilm formation stimulator VEG ATPgrasp_Ter PF15632.6 CCD23471.1 - 0.094 12.5 0.1 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon FeS_assembly_P PF01883.19 CCD23472.1 - 2.7e-06 27.4 0.0 6.1e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein CDP-OH_P_transf PF01066.21 CCD23473.1 - 5.2e-17 62.4 0.1 5.2e-17 62.4 0.1 3.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Myco_haema PF05692.12 CCD23473.1 - 0.12 11.3 0.2 0.17 10.8 0.2 1.1 1 0 0 1 1 1 0 Mycoplasma haemagglutinin DUF4293 PF14126.6 CCD23473.1 - 2.1 8.6 7.8 8.1 6.7 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) NDT80_PhoG PF05224.12 CCD23474.1 - 3.2e-64 216.6 0.2 1.1e-63 214.9 0.2 1.9 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF3605 PF12239.8 CCD23475.1 - 2.8e-41 141.4 7.4 3.4e-41 141.1 7.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) GH-E PF14410.6 CCD23475.1 - 0.03 14.7 1.5 0.29 11.5 0.1 2.8 3 0 0 3 3 3 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues DSRB PF10781.9 CCD23475.1 - 0.096 12.4 0.1 7.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Dextransucrase DSRB SusD_RagB PF07980.11 CCD23476.1 - 0.045 13.4 0.1 0.068 12.8 0.1 1.2 1 0 0 1 1 1 0 SusD family PIR PF00399.19 CCD23476.1 - 0.17 11.5 0.8 0.35 10.5 0.8 1.6 1 0 0 1 1 1 0 Yeast PIR protein repeat CAP_GLY PF01302.25 CCD23478.1 - 4.5e-18 65.0 0.1 8.5e-18 64.1 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 CCD23478.1 - 5.2e-06 26.8 0.0 1.1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain LSM PF01423.22 CCD23479.1 - 6.4e-18 64.2 0.1 9e-18 63.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CCD23479.1 - 0.085 13.0 0.3 0.56 10.4 0.0 2.1 2 0 0 2 2 2 0 RimP C-terminal SH3 domain SM-ATX PF14438.6 CCD23479.1 - 0.13 12.4 0.2 0.29 11.3 0.0 1.6 2 0 0 2 2 2 0 Ataxin 2 SM domain UPRTase PF14681.6 CCD23480.1 - 1.3e-75 253.4 0.0 1.6e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CCD23480.1 - 0.0034 16.9 0.0 0.004 16.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CoA_binding_2 PF13380.6 CCD23480.1 - 0.14 12.6 0.0 0.2 12.2 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain Flu_C_NS1 PF03506.13 CCD23480.1 - 0.16 11.9 0.1 0.26 11.3 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Actin PF00022.19 CCD23481.1 - 2.2e-107 359.2 0.0 1.6e-106 356.3 0.0 1.8 1 1 0 1 1 1 1 Actin MFA1_2 PF17317.2 CCD23482.1 - 7e-26 89.7 0.4 7.4e-26 89.6 0.4 1.0 1 0 0 1 1 1 1 Mating hormone A-factor 1&2 PH PF00169.29 CCD23483.1 - 0.024 15.2 1.2 0.024 15.2 1.2 3.3 3 1 0 3 3 3 0 PH domain Peptidase_M14 PF00246.24 CCD23484.1 - 1.8e-71 241.3 0.2 2.9e-71 240.6 0.2 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Endosulfine PF04667.17 CCD23485.1 - 6.4e-32 109.5 0.1 1.1e-31 108.8 0.1 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region INSIG PF07281.12 CCD23486.1 - 5.7e-17 62.1 4.9 1.8e-16 60.5 4.9 1.8 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) WLM PF08325.10 CCD23487.1 - 6.1e-62 209.1 0.2 8.4e-62 208.6 0.2 1.2 1 0 0 1 1 1 1 WLM domain Pkinase PF00069.25 CCD23488.1 - 5.5e-26 91.5 0.0 1.1e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23488.1 - 2.5e-12 46.7 0.0 4.5e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCD23488.1 - 5.9e-09 35.2 0.0 5.9e-09 35.2 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CCD23488.1 - 0.0033 16.8 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCD23488.1 - 0.13 12.2 0.5 1.5 8.6 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Tuberin PF03542.16 CCD23489.1 - 0.28 10.2 1.3 0.39 9.8 0.8 1.4 1 1 0 1 1 1 0 Tuberin Aminotran_1_2 PF00155.21 CCD23490.1 - 3.4e-13 49.5 0.0 9.3e-13 48.1 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CCD23490.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Kin17_mid PF10357.9 CCD23491.1 - 0.003 17.5 0.2 0.0033 17.3 0.2 1.1 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein Inhibitor_I9 PF05922.16 CCD23491.1 - 0.07 13.8 0.1 0.15 12.7 0.1 1.7 1 1 0 1 1 1 0 Peptidase inhibitor I9 RRM_1 PF00076.22 CCD23492.1 - 1.3e-25 89.0 3.2 2.1e-13 49.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CCD23492.1 - 0.0058 16.7 0.4 0.22 11.6 0.0 3.0 3 1 0 3 3 3 1 RNA binding motif Limkain-b1 PF11608.8 CCD23492.1 - 0.012 15.7 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 Nup35_RRM_2 PF14605.6 CCD23492.1 - 0.017 15.1 0.0 0.16 12.0 0.1 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ysc84 PF04366.12 CCD23493.1 - 3.5e-41 140.0 0.1 5.8e-41 139.2 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 CCD23493.1 - 1.1e-17 63.3 0.0 2.2e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCD23493.1 - 3e-14 52.6 0.0 5.4e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCD23493.1 - 1.1e-12 47.5 0.0 1.9e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PHP PF02811.19 CCD23494.1 - 2.4e-10 40.9 1.6 6.7e-10 39.5 1.6 1.6 1 1 0 1 1 1 1 PHP domain Acetyltransf_13 PF13880.6 CCD23495.1 - 7.3e-21 73.9 0.0 1.3e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 CCD23495.1 - 7.2e-11 41.7 0.2 1.3e-10 40.9 0.2 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 CCD23495.1 - 0.05 13.8 0.0 0.082 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF1281_C PF18406.1 CCD23495.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein Acetyltransf_7 PF13508.7 CCD23495.1 - 0.18 12.3 0.0 0.41 11.1 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DSPn PF14671.6 CCD23496.1 - 2.2e-46 157.8 0.1 5.1e-46 156.6 0.0 1.6 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CCD23496.1 - 6.2e-25 87.6 0.0 4.1e-23 81.7 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCD23496.1 - 0.00052 19.6 0.0 0.00096 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CCD23496.1 - 0.0006 19.5 0.7 0.001 18.7 0.2 1.6 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 CCD23496.1 - 0.035 14.2 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate COMPASS-Shg1 PF05205.12 CCD23498.1 - 1.4e-23 83.5 3.7 1.7e-23 83.2 3.7 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 RhoGAP PF00620.27 CCD23499.1 - 4.1e-42 143.6 0.8 9e-41 139.2 0.0 2.7 3 0 0 3 3 3 1 RhoGAP domain FCH PF00611.23 CCD23499.1 - 4.1e-05 23.8 7.6 0.001 19.3 7.6 3.1 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Sec34 PF04136.15 CCD23499.1 - 1.9 8.3 12.2 0.06 13.2 3.7 2.6 2 1 0 2 2 2 0 Sec34-like family Methyltransf_PK PF05891.12 CCD23500.1 - 2.6e-95 318.1 0.0 2.9e-95 317.9 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 CCD23500.1 - 2.6e-08 34.5 0.0 4.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCD23500.1 - 1.5e-07 31.4 0.0 3.9e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCD23500.1 - 2.1e-05 25.0 0.0 3.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCD23500.1 - 0.004 17.9 0.0 0.0084 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Bin3 PF06859.12 CCD23500.1 - 0.016 15.8 0.0 0.029 15.0 0.0 1.4 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Methyltransf_2 PF00891.18 CCD23500.1 - 0.034 13.5 0.0 0.067 12.5 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 CCD23500.1 - 0.07 12.4 0.0 0.097 11.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AIM5 PF17050.5 CCD23501.1 - 1.4e-06 29.0 0.2 2e-06 28.5 0.2 1.4 1 1 0 1 1 1 1 Altered inheritance of mitochondria 5 YcxB PF14317.6 CCD23501.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 YcxB-like protein SHMT PF00464.19 CCD23502.1 - 7.6e-204 676.8 0.0 9.1e-204 676.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase UreE_N PF02814.15 CCD23502.1 - 0.074 12.7 0.3 5.6 6.7 0.0 2.3 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain Beta_elim_lyase PF01212.21 CCD23502.1 - 0.17 11.2 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Ras PF00071.22 CCD23503.1 - 2.3e-39 134.6 0.4 3.2e-39 134.1 0.4 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD23503.1 - 4.1e-31 107.7 0.8 5.8e-31 107.2 0.4 1.5 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD23503.1 - 7.5e-17 61.3 0.3 1.2e-16 60.7 0.3 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCD23503.1 - 3.8e-10 39.9 0.1 6.4e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CCD23503.1 - 5.3e-09 35.8 0.1 7.4e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CCD23503.1 - 1.1e-07 31.6 0.1 4.5e-07 29.6 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCD23503.1 - 5.4e-07 29.7 0.7 0.0052 16.7 0.1 2.3 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CCD23503.1 - 3.3e-06 26.7 0.2 4.7e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CCD23503.1 - 0.00047 19.7 0.6 0.73 9.3 0.0 2.6 1 1 2 3 3 3 2 Ferrous iron transport protein B AAA_16 PF13191.6 CCD23503.1 - 0.0076 16.7 0.1 0.013 15.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 CCD23503.1 - 0.016 14.4 1.8 0.03 13.5 1.8 1.5 1 1 0 1 1 1 0 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 CCD23503.1 - 0.023 14.7 0.4 0.043 13.8 0.4 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GA-like PF17573.2 CCD23503.1 - 0.027 14.4 1.1 2.2 8.3 0.0 3.3 3 1 0 3 3 3 0 GA-like domain Septin PF00735.18 CCD23503.1 - 0.045 13.0 0.8 0.08 12.2 0.1 1.6 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 CCD23503.1 - 0.073 12.8 1.6 4.1 7.1 1.6 3.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 CCD23503.1 - 0.13 12.6 0.5 0.47 10.9 0.5 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rif1_N PF12231.8 CCD23504.1 - 5e-46 157.4 10.7 1.1e-45 156.3 10.7 1.5 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Pkinase PF00069.25 CCD23505.1 - 2.5e-62 210.6 0.0 3.3e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23505.1 - 1.8e-35 122.5 0.0 2.4e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD23505.1 - 5.5e-10 39.0 0.0 8.8e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CCD23505.1 - 7.4e-06 25.0 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CCD23505.1 - 0.0093 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CCD23505.1 - 0.01 14.9 0.0 0.025 13.6 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Kdo PF06293.14 CCD23505.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UBX PF00789.20 CCD23506.1 - 1.7e-19 69.8 0.1 3.7e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 UBX domain DUF5526 PF17664.1 CCD23506.1 - 0.2 11.2 8.2 0.46 10.0 8.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5526) HSM3_N PF18795.1 CCD23507.1 - 4.4e-112 373.3 20.3 6.8e-112 372.7 20.3 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein HSM3, N terminal domain HSM3_C PF18794.1 CCD23507.1 - 1e-85 285.8 0.5 2.1e-85 284.8 0.5 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein HSM3, C terminal domain Methyltransf_16 PF10294.9 CCD23508.1 - 1.7e-21 76.7 0.6 3e-21 75.9 0.1 1.6 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CCD23508.1 - 7.8e-06 25.8 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCD23508.1 - 7.8e-06 25.8 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CCD23508.1 - 0.00044 19.8 0.0 0.00077 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CCD23508.1 - 0.0066 17.1 0.0 0.011 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain VGPC1_C PF16799.5 CCD23508.1 - 0.053 13.5 1.6 4.1 7.5 0.0 2.8 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Methyltransf_12 PF08242.12 CCD23508.1 - 0.054 14.2 0.0 0.13 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CCD23508.1 - 0.11 13.2 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HbrB PF08539.11 CCD23509.1 - 1.6e-29 103.1 1.4 1.6e-29 103.1 1.4 2.8 2 1 0 2 2 2 1 HbrB-like DUF1674 PF07896.12 CCD23510.1 - 8.9e-18 64.5 4.7 3.3e-17 62.7 4.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Ribosomal_L37 PF08561.10 CCD23511.1 - 5.5e-23 81.8 5.7 4.9e-18 65.8 0.2 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 zf-C2H2_2 PF12756.7 CCD23512.1 - 2.3e-34 117.8 10.9 3e-33 114.1 3.2 2.8 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CCD23512.1 - 0.0026 18.0 2.2 0.58 10.5 0.3 3.0 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Presenilin PF01080.17 CCD23512.1 - 0.19 10.5 12.3 0.37 9.5 12.3 1.5 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CCD23512.1 - 3.3 6.3 9.8 4.7 5.8 9.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-C2H2_4 PF13894.6 CCD23512.1 - 3.9 8.6 8.3 7 7.8 0.1 3.7 3 1 0 3 3 3 0 C2H2-type zinc finger adh_short PF00106.25 CCD23513.1 - 1.2e-18 67.3 0.0 3.9e-10 39.5 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 CCD23513.1 - 1.3e-10 41.5 0.0 2.9e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CCD23513.1 - 0.0022 17.2 0.1 0.0033 16.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 CCD23513.1 - 0.0026 17.3 0.0 0.0063 16.1 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Cyt_b-c1_8 PF10890.8 CCD23514.1 - 0.12 12.8 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Coiled-coil_56 PF09813.9 CCD23514.1 - 0.2 11.7 0.5 0.26 11.4 0.3 1.5 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 Ribosomal_L17 PF01196.19 CCD23515.1 - 9.6e-28 96.9 0.0 2.2e-27 95.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L17 Mrpl_C PF18502.1 CCD23515.1 - 2.4e-21 76.1 3.5 4.9e-21 75.1 3.5 1.5 1 0 0 1 1 1 1 54S ribosomal protein L8 C-terminal domain YqgF PF14639.6 CCD23515.1 - 0.007 16.2 0.7 4.1 7.2 0.0 2.4 2 0 0 2 2 2 2 Holliday-junction resolvase-like of SPT6 DSPc PF00782.20 CCD23516.1 - 2.1e-26 92.3 0.1 1.5e-21 76.6 0.2 3.9 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCD23516.1 - 2.8e-05 23.8 0.0 5.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CCD23516.1 - 0.00055 19.6 0.4 0.0038 16.9 0.2 2.3 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 CCD23516.1 - 0.086 12.9 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 Inositol hexakisphosphate Choline_transpo PF04515.12 CCD23516.1 - 1.6 7.9 4.9 1.8 7.7 0.1 2.2 2 0 0 2 2 2 0 Plasma-membrane choline transporter CBFD_NFYB_HMF PF00808.23 CCD23517.1 - 0.0022 18.2 1.5 0.0026 18.0 0.2 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Paf1 PF03985.13 CCD23518.1 - 1.4e-100 337.3 23.3 1.6e-100 337.1 23.3 1.0 1 0 0 1 1 1 1 Paf1 RNA_polI_A34 PF08208.11 CCD23518.1 - 0.0012 19.0 5.4 0.0012 19.0 5.4 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 zf-C2H2_10 PF16588.5 CCD23520.1 - 8.7e-06 25.4 2.4 1.5e-05 24.6 2.4 1.3 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC_4 PF14392.6 CCD23520.1 - 0.29 10.9 1.2 0.6 9.9 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle RCC1_2 PF13540.6 CCD23521.1 - 1.8e-16 59.5 5.2 7.1e-06 25.7 0.2 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CCD23521.1 - 1.2e-13 51.4 0.3 0.0004 21.0 0.3 5.5 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 CCD23521.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 F-box-like Peptidase_M20 PF01546.28 CCD23522.1 - 3.4e-24 85.7 0.0 2.2e-23 83.1 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CCD23522.1 - 5.1e-12 45.7 0.0 9.8e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.32 CCD23522.1 - 4e-07 30.6 7.7 1.1 10.3 0.0 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD23522.1 - 3.3e-05 24.1 0.0 0.08 13.2 0.0 2.9 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5484 PF17583.2 CCD23522.1 - 0.0017 18.0 1.6 1.2 8.8 0.3 2.7 2 0 0 2 2 2 2 Family of unknown function (DUF5484) MRP-L27 PF09809.9 CCD23523.1 - 1.3e-33 115.2 1.3 1.9e-33 114.7 1.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 SecY PF00344.20 CCD23524.1 - 1.5e-40 139.3 18.4 2.2e-40 138.8 18.4 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CCD23524.1 - 8.1e-10 38.4 0.2 8.1e-10 38.4 0.2 2.6 2 0 0 2 2 2 1 Plug domain of Sec61p A_deaminase PF00962.22 CCD23525.1 - 4.5e-25 88.7 0.1 2.1e-11 43.7 0.0 2.6 3 0 0 3 3 3 2 Adenosine/AMP deaminase Peptidase_M28 PF04389.17 CCD23526.1 - 2.6e-40 138.2 0.0 4e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CCD23526.1 - 1.8e-08 34.3 0.0 3.9e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CCD23526.1 - 0.00045 20.0 0.0 0.00079 19.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 CCD23526.1 - 0.0057 15.7 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Mem_trans PF03547.18 CCD23527.1 - 4.9e-65 219.4 14.3 4e-64 216.4 14.3 1.9 1 1 0 1 1 1 1 Membrane transport protein OATP PF03137.20 CCD23527.1 - 0.013 13.8 0.0 0.022 13.1 0.0 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FixS PF03597.15 CCD23527.1 - 0.55 10.0 7.5 8.4 6.2 0.5 3.2 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DUF2542 PF10808.8 CCD23527.1 - 0.85 10.1 3.5 0.94 10.0 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2542) Cytokin_check_N PF10407.9 CCD23528.1 - 1.8e-31 107.9 1.4 4.7e-31 106.6 1.4 1.8 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus CAP PF00188.26 CCD23530.1 - 1.3e-15 58.4 3.1 3.8e-15 56.9 3.1 1.9 1 0 0 1 1 1 1 Cysteine-rich secretory protein family BAF1_ABF1 PF04684.13 CCD23530.1 - 0.78 8.7 8.6 1.8 7.5 5.4 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF1970 PF09301.10 CCD23530.1 - 7.6 6.8 10.3 2.2 8.6 4.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1970) Ras PF00071.22 CCD23531.1 - 5.4e-55 185.4 1.1 6.4e-55 185.2 1.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD23531.1 - 1.2e-36 125.6 0.1 2e-36 124.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD23531.1 - 5.6e-14 52.0 0.4 8.1e-14 51.5 0.4 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CCD23531.1 - 8.7e-07 28.7 0.2 1.4e-06 27.9 0.2 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CCD23531.1 - 3.2e-06 27.2 0.1 7e-06 26.1 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CCD23531.1 - 7.3e-06 25.5 0.2 9e-06 25.2 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CCD23531.1 - 0.00086 19.3 0.1 0.67 9.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 CCD23531.1 - 0.011 15.0 0.4 2.3 7.3 0.0 2.4 1 1 1 2 2 2 0 G-protein alpha subunit Septin PF00735.18 CCD23531.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 CCD23531.1 - 0.02 15.3 0.0 0.04 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 CCD23531.1 - 0.025 14.0 0.0 0.06 12.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein DUF4287 PF14117.6 CCD23531.1 - 0.14 12.3 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) Mitofilin PF09731.9 CCD23532.1 - 1.4e-36 126.5 21.0 1.6e-32 113.2 20.5 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Enkurin PF13864.6 CCD23532.1 - 0.011 16.1 3.5 0.011 16.1 3.5 4.4 5 1 1 6 6 6 0 Calmodulin-binding DUF1104 PF06518.11 CCD23532.1 - 0.91 9.9 9.3 1.4 9.3 4.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) DUF4709 PF15821.5 CCD23532.1 - 5.6 7.3 11.2 0.18 12.1 2.7 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4709) DUF4407 PF14362.6 CCD23532.1 - 5.6 6.2 7.3 0.53 9.6 2.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) IBR PF01485.21 CCD23533.1 - 2.4e-18 66.1 40.5 8.2e-11 42.0 4.6 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 CCD23533.1 - 2.3e-05 24.2 12.5 2.3e-05 24.2 12.5 4.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) CENP-B_dimeris PF09026.10 CCD23533.1 - 1.7 9.0 10.3 0.037 14.4 2.6 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3808 PF10300.9 CCD23534.1 - 8e-175 582.1 4.1 9.7e-175 581.9 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) HARE-HTH PF05066.13 CCD23534.1 - 0.0037 17.6 0.1 0.079 13.4 0.1 2.6 2 0 0 2 2 2 1 HB1, ASXL, restriction endonuclease HTH domain TPR_2 PF07719.17 CCD23534.1 - 0.026 14.6 0.2 30 5.1 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCD23534.1 - 0.21 12.3 3.6 1.7 9.4 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CCD23534.1 - 1.1 9.8 4.5 1.7 9.2 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCD23534.1 - 4.6 7.6 5.8 5 7.5 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat EF-hand_4 PF12763.7 CCD23535.1 - 0.012 15.5 0.2 0.051 13.5 0.2 2.1 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CCD23535.1 - 0.042 13.4 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 EF hand Vps51 PF08700.11 CCD23536.1 - 6.5e-10 39.0 0.4 6.5e-10 39.0 0.4 2.2 2 0 0 2 2 2 1 Vps51/Vps67 DUF4050 PF13259.6 CCD23536.1 - 0.0043 17.4 0.4 0.0051 17.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) Zw10 PF06248.13 CCD23536.1 - 0.037 12.6 0.3 0.052 12.1 0.3 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Erf4 PF10256.9 CCD23536.1 - 0.05 13.7 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family CDC45 PF02724.14 CCD23536.1 - 1.4 7.1 6.0 1.8 6.8 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein HBS1_N PF08938.10 CCD23536.1 - 9.6 6.6 9.3 53 4.2 9.1 2.3 1 1 0 1 1 1 0 HBS1 N-terminus Arrestin_C PF02752.22 CCD23537.1 - 3.8e-12 46.8 0.1 3.8e-12 46.8 0.1 4.5 4 1 0 5 5 5 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCD23537.1 - 1.9e-08 34.5 6.4 1.7e-06 28.2 0.4 3.2 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain NTR2 PF15458.6 CCD23538.1 - 2.2e-48 165.4 35.7 2.5e-48 165.2 35.7 1.0 1 0 0 1 1 1 1 Nineteen complex-related protein 2 SAPS PF04499.15 CCD23539.1 - 9.5e-173 575.5 10.5 9.5e-173 575.5 10.5 3.9 3 2 1 4 4 4 1 SIT4 phosphatase-associated protein ChAPs PF09295.10 CCD23540.1 - 7e-44 150.4 10.5 4.1e-34 118.3 7.2 2.3 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_1 PF00515.28 CCD23540.1 - 0.0002 21.0 0.9 0.00053 19.7 0.9 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCD23540.1 - 0.00025 21.5 0.0 0.00055 20.4 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD23540.1 - 0.0013 18.9 1.5 0.0052 17.0 1.5 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CCD23540.1 - 0.0086 16.1 0.2 0.043 13.9 0.5 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CCD23540.1 - 0.011 16.0 0.2 0.047 14.1 0.2 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 CCD23540.1 - 0.045 14.0 0.5 0.19 12.0 0.5 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5470 PF17564.2 CCD23540.1 - 2.6 8.3 5.0 16 5.8 3.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5470) GCS PF03074.16 CCD23541.1 - 4.7e-151 503.3 0.1 5.9e-151 503.0 0.1 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Rep_Org_C PF06926.11 CCD23541.1 - 0.1 12.9 1.8 21 5.5 0.0 3.1 2 1 1 3 3 3 0 Putative replisome organiser protein C-terminus IF-2B PF01008.17 CCD23542.1 - 2.1e-75 253.5 0.0 2.4e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 CCD23542.1 - 0.1 12.6 0.1 4.6 7.1 0.0 2.5 2 0 0 2 2 2 0 DeoR C terminal sensor domain Sin_N PF04801.13 CCD23543.1 - 6.2e-20 71.8 2.7 1.7e-19 70.4 2.7 1.7 1 1 0 1 1 1 1 Sin-like protein conserved region tRNA_synt_1c_R2 PF04557.15 CCD23543.1 - 0.02 15.8 2.8 0.049 14.6 2.8 1.6 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DEAD PF00270.29 CCD23544.1 - 1.4e-39 135.6 0.0 3.3e-39 134.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD23544.1 - 8.6e-18 64.7 0.0 2.9e-17 63.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CCD23544.1 - 1.4e-16 60.5 0.0 3.4e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CCD23544.1 - 1.9e-08 34.5 0.4 7e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C2HC5 PF06221.13 CCD23545.1 - 5e-21 74.5 6.1 9.2e-21 73.6 6.1 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Ribosomal_L24e PF01246.20 CCD23545.1 - 0.037 14.2 0.4 3.6 7.9 0.1 2.8 2 0 0 2 2 2 0 Ribosomal protein L24e PHD PF00628.29 CCD23546.1 - 3e-08 33.4 8.3 7.1e-08 32.2 8.3 1.7 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 CCD23546.1 - 3.2e-08 34.1 1.3 3e-07 31.0 1.3 2.7 1 1 0 1 1 1 1 SET domain PHD_2 PF13831.6 CCD23546.1 - 0.015 14.9 3.4 0.03 13.9 3.4 1.5 1 0 0 1 1 1 0 PHD-finger EMP70 PF02990.16 CCD23546.1 - 0.056 12.1 0.1 0.08 11.6 0.1 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 UNC-50 PF05216.13 CCD23547.1 - 9e-89 296.8 22.1 1.1e-88 296.5 22.1 1.1 1 0 0 1 1 1 1 UNC-50 family PLDc PF00614.22 CCD23548.1 - 1.6e-17 62.8 1.1 6.8e-09 35.5 0.4 3.0 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CCD23548.1 - 6.2e-11 42.3 1.0 7.8e-07 29.0 0.1 4.1 4 1 0 4 4 4 2 PLD-like domain PX PF00787.24 CCD23548.1 - 3.3e-05 23.8 1.3 0.095 12.7 0.1 4.2 4 0 0 4 4 4 2 PX domain PH PF00169.29 CCD23548.1 - 0.0024 18.4 1.6 0.0082 16.6 1.6 2.0 1 0 0 1 1 1 1 PH domain GATA PF00320.27 CCD23549.1 - 1.9e-14 52.9 2.6 3.9e-14 52.0 2.6 1.5 1 0 0 1 1 1 1 GATA zinc finger Auto_anti-p27 PF06677.12 CCD23549.1 - 0.12 12.5 1.1 0.21 11.8 1.1 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ArfGap PF01412.18 CCD23549.1 - 0.14 12.2 3.2 0.47 10.6 3.2 1.9 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf Snf7 PF03357.21 CCD23550.1 - 4.2e-09 36.2 21.9 4.2e-09 36.2 21.9 1.4 1 1 0 1 1 1 1 Snf7 BORCS7 PF16088.5 CCD23550.1 - 0.072 13.4 0.7 0.072 13.4 0.7 2.5 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 DUF501 PF04417.12 CCD23550.1 - 0.089 12.6 0.7 0.14 12.0 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DMSP_lyase PF16867.5 CCD23550.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.2 3 0 0 3 3 3 0 Dimethlysulfonioproprionate lyase CPSase_L_D3 PF02787.19 CCD23550.1 - 1.6 9.1 5.9 0.63 10.4 1.7 2.1 2 1 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF948 PF06103.11 CCD23550.1 - 1.8 8.9 10.0 1.5 9.1 0.8 3.0 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 CCD23550.1 - 2.3 8.8 15.8 3.2 8.3 7.4 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region LMBR1 PF04791.16 CCD23550.1 - 2.3 7.0 3.8 2.7 6.8 3.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Cpn60_TCP1 PF00118.24 CCD23551.1 - 6.8e-157 523.0 3.4 7.7e-157 522.8 3.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 CCD23551.1 - 0.046 13.0 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 CCD23552.1 - 4.7e-31 106.4 11.4 1.4e-07 32.1 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD23552.1 - 1.3e-08 35.0 0.1 0.24 11.7 0.1 4.9 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain DASH_Spc34 PF08657.10 CCD23553.1 - 2.8e-87 292.7 10.6 3.3e-87 292.5 10.6 1.1 1 0 0 1 1 1 1 DASH complex subunit Spc34 RNA_Me_trans PF04252.13 CCD23553.1 - 0.054 13.1 1.4 0.11 12.1 1.4 1.5 1 0 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase Peptidase_M22 PF00814.25 CCD23554.1 - 2.1e-84 283.5 0.0 2.5e-84 283.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 CCD23554.1 - 0.0074 16.0 0.0 0.038 13.6 0.0 1.9 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus AA_permease PF00324.21 CCD23555.1 - 6.9e-147 489.9 39.5 7.9e-147 489.7 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD23555.1 - 4.2e-39 134.6 41.3 5.5e-39 134.2 41.3 1.0 1 0 0 1 1 1 1 Amino acid permease Pet100 PF09803.9 CCD23555.1 - 0.0014 19.1 0.1 0.0033 17.9 0.1 1.6 1 0 0 1 1 1 1 Pet100 Keratin_assoc PF09775.9 CCD23555.1 - 0.097 12.3 3.3 0.52 10.0 0.4 2.6 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 SUN PF03856.13 CCD23557.1 - 9.3e-100 333.1 15.8 9.3e-100 333.1 15.8 1.6 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) UEV PF05743.13 CCD23557.1 - 0.041 13.8 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 UEV domain Med3 PF11593.8 CCD23557.1 - 1.5 7.9 8.7 2.4 7.3 8.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MSP1_C PF07462.11 CCD23557.1 - 1.6 7.3 2.8 2.2 6.9 2.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus His_Phos_1 PF00300.22 CCD23558.1 - 1.7e-33 116.0 0.0 2.2e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 CCD23558.1 - 0.042 13.2 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) PET10 PF17316.2 CCD23561.1 - 8.6e-93 310.5 5.4 1.1e-92 310.1 5.4 1.1 1 0 0 1 1 1 1 Petite colonies protein 10 NAP PF00956.18 CCD23562.1 - 5.2e-86 288.2 13.5 5.2e-86 288.2 13.5 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) ArAE_2_N PF10337.9 CCD23563.1 - 2.1e-46 159.0 7.7 2.1e-46 159.0 7.7 4.0 5 1 0 5 5 5 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 CCD23563.1 - 4.8e-13 49.3 14.9 4.8e-13 49.3 14.9 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 CCD23563.1 - 4.4e-06 26.7 0.3 9.6e-06 25.6 0.3 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ALMT PF11744.8 CCD23563.1 - 0.00075 18.5 6.7 0.00075 18.5 6.7 3.7 4 1 0 4 4 4 1 Aluminium activated malate transporter ACR_tran PF00873.19 CCD23563.1 - 0.21 9.2 1.0 0.34 8.5 1.0 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family UFD1 PF03152.14 CCD23564.1 - 4.8e-72 241.0 0.0 6.7e-72 240.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 TPR_2 PF07719.17 CCD23565.1 - 3.9e-11 42.2 20.3 0.13 12.5 0.1 9.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 CCD23565.1 - 3.9e-10 39.1 14.2 0.077 12.8 0.1 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCD23565.1 - 5.3e-10 39.7 8.6 0.0056 17.2 0.1 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCD23565.1 - 9.2e-09 35.5 16.7 0.067 13.5 0.3 6.8 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCD23565.1 - 1.7e-08 34.3 12.3 0.14 12.6 0.2 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 CCD23565.1 - 2e-08 34.4 6.0 0.66 10.7 0.0 6.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 CCD23565.1 - 5.1e-08 33.4 3.6 0.0062 17.2 0.3 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCD23565.1 - 5.1e-07 29.4 18.0 0.0069 16.5 0.1 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD23565.1 - 7.6e-07 29.3 13.2 0.019 15.2 0.2 5.4 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CCD23565.1 - 0.00035 20.6 0.1 0.63 10.2 0.0 4.7 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CCD23565.1 - 0.0033 17.1 5.6 0.11 12.3 0.2 4.3 4 1 0 4 4 4 1 TPR repeat TPR_20 PF14561.6 CCD23565.1 - 0.01 16.2 1.4 3 8.3 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CCD23565.1 - 0.012 16.4 5.4 1.1e+02 4.0 0.1 6.0 5 1 2 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCD23565.1 - 1.2 9.4 9.6 30 5.0 0.1 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF1687 PF07955.11 CCD23566.1 - 5.5e-24 85.1 0.1 6.9e-24 84.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) LSM PF01423.22 CCD23567.1 - 1.1e-15 57.0 0.2 2.3e-15 56.0 0.2 1.5 1 0 0 1 1 1 1 LSM domain Peptidase_S49_N PF08496.10 CCD23567.1 - 0.072 13.1 7.8 0.067 13.3 2.4 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal U3_snoRNA_assoc PF08297.11 CCD23567.1 - 3.1 8.6 11.3 4.6 8.0 0.2 2.2 2 0 0 2 2 2 0 U3 snoRNA associated TrkH PF02386.16 CCD23569.1 - 1.8e-160 534.7 1.4 6.3e-160 532.9 0.0 2.2 2 1 0 2 2 2 1 Cation transport protein Zip PF02535.22 CCD23569.1 - 0.14 11.4 0.0 0.35 10.0 0.0 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter Connexin PF00029.19 CCD23569.1 - 5.9 6.6 5.6 0.42 10.3 0.2 1.8 2 0 0 2 2 2 0 Connexin Solute_trans_a PF03619.16 CCD23570.1 - 1.5e-71 241.1 13.8 1.8e-71 240.8 13.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Mito_carr PF00153.27 CCD23571.1 - 2.1e-61 203.9 1.2 5.1e-21 74.4 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein AAA_6 PF12774.7 CCD23572.1 - 6e-99 331.1 0.2 2.8e-97 325.6 0.0 3.6 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CCD23572.1 - 1.6e-80 271.2 8.3 1.6e-80 271.2 8.3 5.9 7 0 0 7 7 6 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CCD23572.1 - 7.1e-51 173.5 18.6 7.1e-51 173.5 18.6 4.4 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 CCD23572.1 - 2.1e-46 157.8 2.1 2.1e-46 157.8 2.1 5.8 7 0 0 7 7 6 1 ATP-binding dynein motor region AAA_8 PF12780.7 CCD23572.1 - 1e-42 146.3 0.9 4.4e-42 144.2 0.3 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CCD23572.1 - 2.6e-33 115.1 0.2 5.5e-29 100.9 0.0 4.0 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_5 PF07728.14 CCD23572.1 - 1.2e-22 80.3 0.2 1.1e-08 35.1 0.0 5.1 4 1 0 4 4 3 3 AAA domain (dynein-related subfamily) MT PF12777.7 CCD23572.1 - 2e-21 76.4 3.4 4.5e-21 75.3 3.4 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CCD23572.1 - 3.4e-17 62.7 0.5 2e-16 60.3 0.1 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CCD23572.1 - 1.8e-16 60.3 0.9 3.9e-14 52.8 0.0 3.9 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 CCD23572.1 - 2e-12 47.6 3.4 9.7e-05 22.7 0.0 6.6 5 0 0 5 5 5 2 AAA domain AAA PF00004.29 CCD23572.1 - 2.9e-10 40.7 0.0 0.0064 16.9 0.0 4.5 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCD23572.1 - 7.2e-09 36.2 0.1 0.03 14.7 0.0 5.0 4 0 0 4 4 3 2 AAA ATPase domain AAA_18 PF13238.6 CCD23572.1 - 8.3e-06 26.4 0.5 0.78 10.3 0.0 4.7 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 CCD23572.1 - 3e-05 24.2 0.1 0.21 11.8 0.0 4.6 5 0 0 5 5 4 1 AAA domain AAA_lid_1 PF17857.1 CCD23572.1 - 3.2e-05 24.1 0.0 0.0002 21.5 0.0 2.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_30 PF13604.6 CCD23572.1 - 7.3e-05 22.6 0.3 6.3 6.5 0.0 4.2 5 0 0 5 5 4 0 AAA domain IstB_IS21 PF01695.17 CCD23572.1 - 0.00011 21.9 0.4 0.58 9.9 0.0 4.2 3 1 1 4 4 3 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CCD23572.1 - 0.00017 21.9 0.1 4.8 7.6 0.0 4.2 3 0 0 3 3 3 1 RNA helicase AAA_19 PF13245.6 CCD23572.1 - 0.00048 20.5 1.9 2 8.7 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_24 PF13479.6 CCD23572.1 - 0.0006 19.6 2.4 2.5 7.8 0.1 3.7 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 CCD23572.1 - 0.0007 19.5 0.4 0.37 10.7 0.0 3.6 3 0 0 3 3 2 1 RsgA GTPase T2SSE PF00437.20 CCD23572.1 - 0.0012 17.9 0.3 0.19 10.8 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein TsaE PF02367.17 CCD23572.1 - 0.01 15.9 0.9 11 6.1 0.0 3.7 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CCD23572.1 - 0.021 14.2 0.2 1.3 8.3 0.0 3.2 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CCD23572.1 - 0.026 13.8 0.0 2.1 7.6 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.6 CCD23572.1 - 0.032 13.8 0.0 0.61 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CCD23572.1 - 0.058 13.1 0.5 2.9 7.7 0.0 3.2 3 0 0 3 3 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CCD23572.1 - 0.068 12.5 0.2 0.74 9.1 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 CCD23572.1 - 0.073 13.0 3.2 7.9 6.4 0.1 3.7 3 0 0 3 3 2 0 NACHT domain AAA_28 PF13521.6 CCD23572.1 - 0.074 13.3 1.1 47 4.2 0.0 4.0 4 0 0 4 4 3 0 AAA domain ABC_tran PF00005.27 CCD23572.1 - 0.09 13.3 8.4 0.95 10.0 0.1 4.5 4 0 0 4 4 3 0 ABC transporter cobW PF02492.19 CCD23572.1 - 0.12 11.9 1.0 0.48 10.0 0.1 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1192 PF06698.11 CCD23572.1 - 1.7 8.8 6.3 0.67 10.0 2.3 2.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1192) Ras PF00071.22 CCD23573.1 - 2.9e-50 170.0 0.0 4e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD23573.1 - 7.7e-24 84.2 0.0 1.8e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD23573.1 - 2.3e-08 33.7 0.0 3.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCD23573.1 - 0.002 18.2 0.0 0.0037 17.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCD23573.1 - 0.0075 16.2 0.2 0.22 11.4 0.0 2.5 1 1 2 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 CCD23573.1 - 0.027 13.8 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TEA PF01285.18 CCD23573.1 - 0.15 12.1 0.0 0.82 9.8 0.0 2.2 3 0 0 3 3 3 0 TEA/ATTS domain tRNA_U5-meth_tr PF05958.11 CCD23574.1 - 6.6e-23 81.3 0.4 8.1e-22 77.7 0.4 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 CCD23574.1 - 2.1e-11 43.7 0.1 4.3e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.6 CCD23574.1 - 1.3e-07 31.5 0.0 3.2e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCD23574.1 - 3.6e-06 27.6 0.1 1.1e-05 26.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 CCD23574.1 - 1.5e-05 24.7 0.0 3.8e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 CCD23574.1 - 2.4e-05 23.9 0.0 4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 CCD23574.1 - 0.00011 21.9 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.18 CCD23574.1 - 0.00023 20.6 0.1 0.0051 16.2 0.0 2.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CCD23574.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF2606 PF10794.9 CCD23574.1 - 0.0078 16.0 0.1 0.064 13.0 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2606) Methyltransf_11 PF08241.12 CCD23574.1 - 0.0079 16.8 0.0 0.031 14.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 CCD23574.1 - 0.021 14.3 0.0 0.058 12.9 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase Met_10 PF02475.16 CCD23574.1 - 0.022 14.5 0.0 0.075 12.8 0.0 1.9 2 0 0 2 2 2 0 Met-10+ like-protein Ribosomal_S21e PF01249.18 CCD23575.1 - 2.8e-33 113.9 0.0 3.5e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e VCH_CASS14 PF18315.1 CCD23575.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 Integron cassette protein VCH_CASS1 chain Glyco_hydro2_C5 PF18565.1 CCD23575.1 - 0.12 12.2 0.1 0.15 11.9 0.1 1.1 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_transf_8 PF01501.20 CCD23576.1 - 3.3e-28 98.9 3.3 3.5e-28 98.9 0.1 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 8 DUF1460 PF07313.12 CCD23576.1 - 0.067 12.6 0.3 0.15 11.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) DEAD PF00270.29 CCD23577.1 - 4.2e-44 150.4 1.3 5e-44 150.1 0.3 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD23577.1 - 3.3e-31 107.9 0.2 1e-30 106.4 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD23577.1 - 2.3e-07 31.0 0.0 4.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CCD23577.1 - 0.00082 19.1 0.1 0.0014 18.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCD23577.1 - 0.0013 19.0 0.2 0.019 15.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain Ribosomal_L1 PF00687.21 CCD23578.1 - 5.7e-41 140.5 0.9 7.2e-41 140.2 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SEA PF01390.20 CCD23578.1 - 0.039 14.0 0.0 0.59 10.2 0.0 2.3 2 0 0 2 2 2 0 SEA domain Phosducin PF02114.16 CCD23579.1 - 4.9e-07 29.0 0.1 5.9e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 CCD23579.1 - 0.00075 19.5 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.16 CCD23579.1 - 0.082 12.7 1.4 0.37 10.6 0.1 2.0 1 1 1 2 2 2 0 Mitosis protein DIM1 SAS4 PF15460.6 CCD23580.1 - 0.064 13.4 3.7 0.15 12.1 0.4 2.8 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 NOA36 PF06524.12 CCD23581.1 - 0.59 9.4 16.4 0.21 10.9 12.9 2.1 2 0 0 2 2 2 0 NOA36 protein SIR2 PF02146.17 CCD23582.1 - 8.8e-32 110.4 0.0 1.2e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF2024 PF09630.10 CCD23582.1 - 0.11 12.4 0.1 0.71 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) zf_CCCH_4 PF18345.1 CCD23583.1 - 6.4e-07 29.2 5.6 1.3e-06 28.3 5.6 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CCD23583.1 - 8.1e-05 22.4 2.8 0.00015 21.6 2.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CCD23583.1 - 0.00019 22.1 0.3 0.00043 21.0 0.3 1.5 1 0 0 1 1 1 1 Torus domain Nucleoporin_FG PF13634.6 CCD23583.1 - 0.00056 20.7 26.7 0.00056 20.7 26.7 5.2 2 1 3 5 5 5 2 Nucleoporin FG repeat region zf-CCCH_4 PF18044.1 CCD23583.1 - 0.00057 19.6 1.0 0.0011 18.7 1.0 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CCD23583.1 - 0.029 14.8 2.7 0.058 13.9 2.7 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CCD23583.1 - 0.12 12.6 0.3 0.32 11.2 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger containing family Glycos_transf_3 PF00591.21 CCD23584.1 - 1.2e-79 267.5 0.0 1.6e-79 267.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 CCD23584.1 - 5.9e-14 51.7 0.1 1.1e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Spc110_C PF18520.1 CCD23585.1 - 2e-27 94.5 4.1 2e-27 94.5 4.1 3.5 4 0 0 4 4 4 1 Spindle pole body component 110 C-terminal domain Spc7 PF08317.11 CCD23585.1 - 1.5e-05 24.0 25.2 1.5e-05 24.0 25.2 6.7 1 1 6 7 7 7 3 Spc7 kinetochore protein GAS PF13851.6 CCD23585.1 - 0.0021 17.4 20.4 0.0021 17.4 20.4 6.7 3 2 1 6 6 6 3 Growth-arrest specific micro-tubule binding Uds1 PF15456.6 CCD23585.1 - 0.0033 17.6 13.3 0.0033 17.6 13.3 8.4 3 2 3 6 6 6 1 Up-regulated During Septation PACT_coil_coil PF10495.9 CCD23585.1 - 0.035 14.7 0.0 0.035 14.7 0.0 3.9 4 0 0 4 4 4 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Filament PF00038.21 CCD23585.1 - 0.63 9.6 134.2 0.24 10.9 11.3 5.8 2 2 1 4 4 4 0 Intermediate filament protein TMF_TATA_bd PF12325.8 CCD23585.1 - 2.4 8.4 108.7 2.1 8.6 8.2 10.3 2 2 6 8 8 8 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 CCD23585.1 - 8.4 5.6 91.2 2.4 7.4 17.1 6.1 2 1 3 5 5 5 0 Domain of unknown function (DUF4407) CLTH PF10607.9 CCD23586.1 - 0.0076 16.1 1.1 0.0092 15.9 1.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain VHS PF00790.19 CCD23587.1 - 8.4e-48 161.8 0.1 4.8e-47 159.4 0.0 2.2 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 CCD23587.1 - 2.2e-22 79.4 0.4 6.5e-22 77.9 0.4 1.9 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 CCD23587.1 - 2.8e-19 69.2 1.5 8.4e-19 67.7 0.4 2.4 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 CCD23587.1 - 1.7e-06 27.5 0.4 4.8e-06 26.1 0.4 1.8 1 0 0 1 1 1 1 GGA N-GAT domain HSA PF07529.13 CCD23588.1 - 1.9e-10 40.9 0.1 1.9e-10 40.9 0.1 2.6 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.6 CCD23588.1 - 5.5e-09 36.1 0.3 5.5e-09 36.1 0.3 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CCD23588.1 - 0.00025 21.2 0.0 0.00085 19.5 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain BCIP PF13862.6 CCD23589.1 - 2.4e-48 164.7 2.7 2.4e-48 164.7 2.7 1.4 2 0 0 2 2 2 1 p21-C-terminal region-binding protein RPN2_C PF18004.1 CCD23589.1 - 5.6 6.9 7.8 0.23 11.4 0.4 2.0 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain ThiF PF00899.21 CCD23590.1 - 2.1e-56 191.0 0.0 3e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 CCD23590.1 - 1.8e-10 41.3 0.0 7.1e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 CCD23590.1 - 0.0033 17.5 0.0 0.0091 16.1 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Cys_Met_Meta_PP PF01053.20 CCD23592.1 - 2.6e-66 223.7 0.0 7.3e-66 222.3 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CCD23592.1 - 2.3e-06 26.8 0.0 5.4e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CCD23592.1 - 0.0009 18.5 0.0 0.0017 17.6 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Rad60-SLD PF11976.8 CCD23593.1 - 4.3e-25 87.3 8.2 9.8e-25 86.2 2.1 3.5 2 1 1 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CCD23593.1 - 0.01 15.5 0.4 0.01 15.5 0.4 2.1 2 0 0 2 2 2 0 Ubiquitin family DSS1_SEM1 PF05160.13 CCD23594.1 - 2.3e-20 72.4 13.7 3.4e-20 71.9 13.7 1.3 1 0 0 1 1 1 1 DSS1/SEM1 family AAA PF00004.29 CCD23595.1 - 1.8e-41 141.7 0.0 4.5e-41 140.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CCD23595.1 - 4.7e-21 74.5 0.3 9.8e-21 73.5 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CCD23595.1 - 7.8e-09 35.2 0.0 1.9e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CCD23595.1 - 1.9e-05 25.2 0.1 0.016 15.6 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 CCD23595.1 - 4.1e-05 23.8 0.0 0.00025 21.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CCD23595.1 - 5.9e-05 23.1 0.7 0.00024 21.1 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CCD23595.1 - 0.00094 19.0 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCD23595.1 - 0.0033 17.7 2.3 0.051 13.9 0.4 2.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CCD23595.1 - 0.0039 17.4 0.1 0.028 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 CCD23595.1 - 0.0074 15.8 0.2 0.073 12.5 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.13 CCD23595.1 - 0.015 14.5 0.0 0.047 12.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CCD23595.1 - 0.016 14.6 0.1 0.041 13.3 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CCD23595.1 - 0.03 14.0 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 CCD23595.1 - 0.035 13.9 0.6 0.3 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CCD23595.1 - 0.056 13.8 0.5 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CCD23595.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region TolA_bind_tri PF16331.5 CCD23595.1 - 0.11 12.5 6.2 0.16 12.0 3.3 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation AAA_24 PF13479.6 CCD23595.1 - 0.13 11.9 0.9 0.4 10.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain Fez1 PF06818.15 CCD23595.1 - 2.4 8.6 8.4 5.2 7.5 5.3 2.4 2 1 0 2 2 2 0 Fez1 Cep57_CLD_2 PF14197.6 CCD23595.1 - 5.3 7.2 7.8 2.8 8.1 4.0 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 WD40 PF00400.32 CCD23596.1 - 4.5e-29 100.1 10.4 3e-08 34.2 0.2 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD23596.1 - 5.9e-10 39.3 0.1 0.015 15.6 0.0 4.1 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain NUC153 PF08159.12 CCD23597.1 - 1.1e-13 50.7 19.7 1.4e-13 50.4 4.6 3.5 4 0 0 4 4 4 2 NUC153 domain RIO1 PF01163.22 CCD23598.1 - 7e-70 234.5 3.8 7e-70 234.5 3.8 2.3 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 CCD23598.1 - 0.029 14.3 0.1 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family YL1 PF05764.13 CCD23598.1 - 0.042 14.0 36.8 0.099 12.7 27.9 2.2 2 0 0 2 2 2 0 YL1 nuclear protein DUF4159 PF13709.6 CCD23598.1 - 0.044 13.2 0.5 0.087 12.2 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4159) CDC45 PF02724.14 CCD23598.1 - 4.6 5.4 29.0 1 7.6 22.7 2.0 2 0 0 2 2 2 0 CDC45-like protein Kei1 PF08552.11 CCD23599.1 - 1.7e-19 70.4 14.6 1.2e-11 44.8 8.6 2.1 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 Aldo_ket_red PF00248.21 CCD23600.1 - 7e-43 146.9 0.0 6.4e-41 140.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SpoU_sub_bind PF08032.12 CCD23600.1 - 0.056 13.7 0.4 12 6.2 0.0 3.8 4 1 1 5 5 5 0 RNA 2'-O ribose methyltransferase substrate binding BHD_3 PF10405.9 CCD23600.1 - 0.14 12.5 0.0 1.7 9.1 0.0 2.6 3 0 0 3 3 3 0 Rad4 beta-hairpin domain 3 FHA PF00498.26 CCD23601.1 - 1.1e-05 25.7 0.1 3.1e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 FHA domain GlutR_dimer PF00745.20 CCD23601.1 - 0.12 12.8 0.9 7.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain RAI1 PF08652.11 CCD23602.1 - 0.0012 19.0 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease YCII PF03795.14 CCD23603.1 - 0.0018 18.6 0.0 0.0022 18.3 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Glyco_hydro_18 PF00704.28 CCD23604.1 - 1.7e-70 238.3 7.4 1.7e-70 238.3 7.4 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DUF4834 PF16118.5 CCD23604.1 - 0.02 15.8 0.1 0.054 14.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Trimer_CC PF08954.11 CCD23604.1 - 0.043 13.4 0.3 0.076 12.6 0.3 1.4 1 0 0 1 1 1 0 Trimerisation motif Folate_carrier PF01770.18 CCD23604.1 - 0.045 12.5 0.0 0.067 11.9 0.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier Sclerostin PF05463.11 CCD23604.1 - 0.074 12.8 0.4 0.14 11.9 0.4 1.4 1 0 0 1 1 1 0 Sclerostin (SOST) GPP34 PF05719.11 CCD23605.1 - 3.5e-66 223.1 0.0 4.4e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) EF-hand_1 PF00036.32 CCD23607.1 - 1.6e-26 89.8 6.2 4.1e-08 32.2 0.4 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CCD23607.1 - 1.1e-23 81.0 5.4 1.5e-06 27.6 0.5 4.9 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 CCD23607.1 - 6.8e-23 80.9 9.2 1e-16 61.2 0.4 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CCD23607.1 - 2.2e-18 64.8 4.1 3.8e-05 23.0 0.5 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CCD23607.1 - 9.4e-17 60.6 10.7 5.3e-07 29.4 0.8 3.7 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CCD23607.1 - 0.00029 20.7 5.8 2.1 8.4 0.2 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CCD23607.1 - 0.0011 19.2 0.4 0.03 14.6 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CCD23607.1 - 0.0055 17.0 2.0 0.25 11.7 0.2 3.1 1 1 2 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.15 CCD23607.1 - 0.085 12.9 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_13 PF17958.1 CCD23607.1 - 0.094 12.5 0.1 4.3 7.2 0.0 3.2 4 1 0 4 4 4 0 EF-hand domain Acyltransferase PF01553.21 CCD23608.1 - 0.0046 16.6 0.0 0.012 15.3 0.0 1.6 1 1 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.21 CCD23609.1 - 9.7e-14 51.1 0.0 1.4e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Kinesin PF00225.23 CCD23610.1 - 1.5e-100 336.4 14.2 1.5e-100 336.4 14.2 3.0 3 2 1 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 CCD23610.1 - 1.5e-55 187.2 0.9 1.5e-55 187.2 0.9 2.5 3 1 0 3 3 3 1 Microtubule binding PKcGMP_CC PF16808.5 CCD23610.1 - 0.039 13.8 11.5 3 7.8 0.4 3.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Rrp15p PF07890.12 CCD23611.1 - 8.9e-31 107.0 12.6 8.9e-31 107.0 12.6 2.2 2 1 0 2 2 2 1 Rrp15p SDA1 PF05285.12 CCD23611.1 - 0.49 9.8 29.6 0.63 9.4 29.6 1.1 1 0 0 1 1 1 0 SDA1 Ndc1_Nup PF09531.10 CCD23611.1 - 1.1 7.8 4.1 1.3 7.6 4.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Metallophos PF00149.28 CCD23612.1 - 3.5e-34 119.1 0.1 5.9e-34 118.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CCD23612.1 - 9.1e-23 80.4 0.2 8.7e-22 77.2 0.0 2.3 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 CCD23612.1 - 3.4e-17 61.5 4.9 5.7e-07 29.1 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CCD23612.1 - 5e-14 51.2 0.7 4.8e-05 23.2 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCD23612.1 - 1.1e-10 41.0 0.9 5.9e-06 25.9 0.2 2.9 2 0 0 2 2 2 2 TPR repeat TPR_9 PF13371.6 CCD23612.1 - 2.6e-07 30.7 0.0 3.9e-05 23.7 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCD23612.1 - 1.5e-06 28.0 3.9 0.002 18.2 0.7 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCD23612.1 - 1.4e-05 25.1 0.4 0.11 12.9 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF1563 PF07599.11 CCD23612.1 - 0.0034 17.4 0.6 0.012 15.7 0.6 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1563) TPR_19 PF14559.6 CCD23612.1 - 0.021 15.3 0.2 0.11 13.1 0.1 2.1 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCD23612.1 - 0.047 13.7 0.2 0.33 11.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCD23612.1 - 0.049 13.7 3.9 0.27 11.3 0.1 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 CCD23612.1 - 0.049 13.7 3.6 0.17 12.0 2.8 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 CCD23612.1 - 0.072 13.4 1.2 1.1 9.6 0.0 2.6 2 1 1 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD23612.1 - 0.1 12.8 1.8 9.5 6.5 0.9 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CCD23612.1 - 0.22 12.2 0.0 10 6.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CBF PF03914.17 CCD23613.1 - 1.4e-31 109.8 1.3 1.4e-31 109.8 1.3 2.1 2 1 0 2 2 2 1 CBF/Mak21 family Asn_synthase PF00733.21 CCD23614.1 - 4.3e-94 316.1 0.6 1.5e-90 304.4 0.6 2.1 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 CCD23614.1 - 1.1e-33 115.8 0.0 1.7e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CCD23614.1 - 2.1e-28 99.2 0.0 3.8e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CCD23614.1 - 1.7e-06 27.7 0.0 3.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 CCD23614.1 - 0.0032 16.6 0.0 0.0058 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD synthase LIDHydrolase PF10230.9 CCD23616.1 - 3.9e-58 197.1 2.3 4.5e-58 196.9 2.3 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF3089 PF11288.8 CCD23616.1 - 0.043 13.3 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) XTBD PF11952.8 CCD23616.1 - 0.062 13.1 0.3 0.15 11.8 0.3 1.6 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD Hydrolase_4 PF12146.8 CCD23616.1 - 0.068 12.4 0.0 0.82 8.9 0.0 2.4 3 0 0 3 3 3 0 Serine aminopeptidase, S33 BAR_2 PF10455.9 CCD23618.1 - 2.7e-88 295.9 61.0 7.1e-66 222.3 44.2 2.5 1 1 1 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 CCD23618.1 - 0.00029 20.6 42.8 0.00046 19.9 24.1 3.7 3 1 0 3 3 3 3 BAR domain MARVEL PF01284.23 CCD23620.1 - 1.1e-25 90.4 16.5 1.4e-25 90.0 16.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Pet20 PF08692.10 CCD23621.1 - 3.3e-47 160.4 3.5 6.8e-47 159.4 3.5 1.5 1 0 0 1 1 1 1 Mitochondrial protein Pet20 Pheromone PF08015.11 CCD23621.1 - 7.4 7.7 11.2 14 6.8 7.2 2.3 2 0 0 2 2 2 0 Fungal mating-type pheromone WW PF00397.26 CCD23622.1 - 4.8e-12 45.8 9.7 3e-10 40.0 5.8 3.1 3 0 0 3 3 3 2 WW domain FF PF01846.19 CCD23622.1 - 1.4e-09 38.0 1.8 5.3e-09 36.1 1.8 2.1 1 0 0 1 1 1 1 FF domain Citrate_synt PF00285.21 CCD23622.1 - 0.054 12.6 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain SH3_1 PF00018.28 CCD23624.1 - 1.7e-15 56.3 0.0 2.8e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCD23624.1 - 3.8e-13 49.1 0.0 5.9e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCD23624.1 - 3.2e-10 39.5 0.0 4.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain TFIIA PF03153.13 CCD23624.1 - 0.26 11.2 18.1 0.31 11.0 18.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2076 PF09849.9 CCD23624.1 - 3.2 7.7 18.9 7.7 6.5 18.9 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.13 CCD23624.1 - 3.3 8.4 20.8 0.74 10.5 16.6 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NCA2 PF08637.10 CCD23625.1 - 2e-99 332.4 4.0 2e-99 332.4 4.0 1.9 3 0 0 3 3 3 1 ATP synthase regulation protein NCA2 SelP_N PF04592.14 CCD23626.1 - 8.1 5.8 16.7 1.9 7.8 12.9 1.8 2 0 0 2 2 2 0 Selenoprotein P, N terminal region SKN1 PF03935.15 CCD23627.1 - 9.1e-254 842.4 7.4 1.2e-253 842.0 7.4 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Phosphorylase PF00343.20 CCD23628.1 - 0 1041.8 0.1 0 1041.6 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Mrr_cat_2 PF13156.6 CCD23628.1 - 0.073 13.0 1.8 0.22 11.4 0.3 2.5 2 0 0 2 2 2 0 Restriction endonuclease CDP-OH_P_transf PF01066.21 CCD23629.1 - 6.8e-11 42.8 3.0 7.4e-11 42.7 0.4 2.1 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SR-25 PF10500.9 CCD23630.1 - 0.12 12.0 8.6 0.19 11.3 8.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Orf78 PF06024.12 CCD23630.1 - 0.96 9.8 4.9 1.8 8.9 4.5 1.8 1 1 0 1 1 1 0 Orf78 (ac78) Macoilin PF09726.9 CCD23630.1 - 3.2 6.2 9.3 3.2 6.2 9.3 1.1 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 CCD23630.1 - 3.5 5.9 9.4 4.4 5.5 9.4 1.2 1 0 0 1 1 1 0 Menin Clathrin PF00637.20 CCD23631.1 - 8.7e-186 609.3 53.8 2.4e-32 111.7 0.1 8.1 9 0 0 9 9 9 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 CCD23631.1 - 9.5e-27 92.7 0.9 5.9e-26 90.2 0.3 2.8 3 0 0 3 3 3 1 Clathrin-H-link Clathrin_propel PF01394.20 CCD23631.1 - 2.5e-23 81.2 4.8 5.5e-06 26.4 0.2 6.0 5 0 0 5 5 5 5 Clathrin propeller repeat Clathrin-link PF09268.10 CCD23631.1 - 1.5e-08 33.8 0.5 1.5e-08 33.8 0.5 2.9 3 0 0 3 3 3 1 Clathrin, heavy-chain linker TPR_7 PF13176.6 CCD23631.1 - 7.4 6.9 9.4 21 5.5 0.0 5.8 8 0 0 8 8 8 0 Tetratricopeptide repeat FACT-Spt16_Nlob PF14826.6 CCD23632.1 - 4.7e-49 166.3 0.5 4.7e-49 166.3 0.5 2.8 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 CCD23632.1 - 6.9e-48 162.6 0.1 6.9e-48 162.6 0.1 2.2 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 CCD23632.1 - 3.8e-29 101.9 0.0 8.1e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 CCD23632.1 - 3.4e-13 49.8 0.5 1.5e-12 47.7 0.1 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PPP4R2 PF09184.11 CCD23632.1 - 0.88 9.1 18.3 0.9 9.1 2.9 2.6 2 0 0 2 2 2 0 PPP4R2 AMPK1_CBM PF16561.5 CCD23633.1 - 1.7e-29 101.8 0.1 8.7e-29 99.6 0.0 2.3 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 CCD23633.1 - 6.7e-28 96.8 2.4 6.7e-28 96.8 2.4 2.9 3 1 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interaction domain Pex14_N PF04695.13 CCD23633.1 - 9.4 6.9 30.4 0.44 11.2 7.5 3.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C2H2 PF00096.26 CCD23634.1 - 4.2e-05 23.8 24.4 0.00011 22.4 4.7 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD23634.1 - 7e-05 23.3 16.6 0.026 15.3 2.8 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCD23634.1 - 0.00043 20.6 26.5 0.0031 17.9 8.8 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CCD23634.1 - 0.16 12.3 14.9 0.41 11.0 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding LSM PF01423.22 CCD23635.1 - 9.3e-21 73.3 0.7 1.6e-20 72.5 0.7 1.4 1 0 0 1 1 1 1 LSM domain Menin PF05053.13 CCD23635.1 - 0.22 9.8 3.2 0.27 9.6 3.2 1.0 1 0 0 1 1 1 0 Menin CHZ PF09649.10 CCD23636.1 - 5.3e-20 70.6 2.0 5.3e-20 70.6 2.0 2.3 3 0 0 3 3 3 1 Histone chaperone domain CHZ TT_ORF2 PF02957.15 CCD23636.1 - 7.4 7.5 12.8 1.5 9.8 6.6 2.2 2 0 0 2 2 2 0 TT viral ORF2 DUF5364 PF17322.2 CCD23639.1 - 3.3e-40 138.4 37.1 9.4e-39 133.6 37.1 2.0 1 1 0 1 1 1 1 Family of unknown function (DUF5364) DUF1717 PF05414.11 CCD23639.1 - 0.054 13.9 0.2 0.11 12.9 0.2 1.5 1 0 0 1 1 1 0 Viral domain of unknown function (DUF1717) MSL1_dimer PF16801.5 CCD23639.1 - 0.45 10.3 23.7 1.5 8.7 3.0 2.8 2 0 0 2 2 2 0 Dimerisation domain of Male-specific-Lethal 1 ApoO PF09769.9 CCD23639.1 - 2.4 8.1 4.9 4.5 7.3 4.9 1.4 1 0 0 1 1 1 0 Apolipoprotein O PNRC PF15365.6 CCD23640.1 - 0.00036 20.3 1.8 0.00036 20.3 1.8 2.7 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif P_C PF06640.11 CCD23640.1 - 0.75 9.9 5.4 0.28 11.3 1.5 1.8 1 1 1 2 2 2 0 P protein C-terminus GREB1 PF15782.5 CCD23640.1 - 0.96 6.5 12.1 1.1 6.3 12.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Nse5 PF08691.10 CCD23641.1 - 1.5e-20 73.4 31.2 2.6e-13 49.5 3.6 2.4 3 0 0 3 3 3 2 DNA repair proteins Nse5 and Nse6 Securin PF04856.13 CCD23641.1 - 0.24 11.3 8.7 0.48 10.4 8.7 1.5 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor CDC45 PF02724.14 CCD23641.1 - 5 5.3 10.6 1.9 6.7 8.3 1.4 2 0 0 2 2 2 0 CDC45-like protein EamA PF00892.20 CCD23642.1 - 3.7e-12 46.6 28.4 1.7e-07 31.5 5.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CCD23642.1 - 6.1e-06 25.6 21.5 7.5e-06 25.4 20.5 1.7 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 CCD23642.1 - 0.077 12.3 22.0 0.21 10.9 0.6 2.1 1 1 1 2 2 2 0 Triose-phosphate Transporter family Multi_Drug_Res PF00893.19 CCD23642.1 - 0.9 10.2 8.6 6.1 7.6 3.5 3.1 2 1 0 2 2 2 0 Small Multidrug Resistance protein GATA PF00320.27 CCD23643.1 - 7.3e-17 60.7 5.4 1.9e-16 59.4 5.4 1.8 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 CCD23643.1 - 0.14 11.7 0.9 0.37 10.3 0.9 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding Glyco_transf_21 PF13506.6 CCD23644.1 - 0.042 13.3 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 XPG_I PF00867.18 CCD23645.1 - 2.2e-24 85.6 0.1 9.3e-24 83.6 0.0 2.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 CCD23645.1 - 1.2e-05 25.8 0.0 3.8e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CCD23645.1 - 0.057 12.9 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 XPG domain containing PMSR PF01625.21 CCD23646.1 - 2.2e-51 174.1 0.3 2.6e-51 173.8 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF3889 PF13028.6 CCD23646.1 - 0.012 15.5 0.4 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3889) AdoHcyase PF05221.17 CCD23647.1 - 1.7e-129 431.3 0.0 8.5e-75 251.7 0.3 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CCD23647.1 - 2e-85 284.8 2.9 3.2e-85 284.1 2.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CCD23647.1 - 3.3e-08 33.1 0.1 6.2e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CCD23647.1 - 0.00035 20.2 0.2 0.00067 19.3 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CCD23647.1 - 0.0016 18.7 0.1 0.0033 17.7 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Oxidored_nitro PF00148.19 CCD23647.1 - 0.0058 15.4 0.5 0.37 9.5 0.1 2.8 3 0 0 3 3 3 1 Nitrogenase component 1 type Oxidoreductase DUF2572 PF10833.8 CCD23647.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) RVT_2 PF07727.14 CCD23648.1 - 1.1e-33 116.9 0.1 2.1e-33 116.0 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CCD23648.1 - 8.5e-16 58.2 0.0 2.4e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CCD23648.1 - 9.9e-06 25.3 0.4 4.1e-05 23.4 0.4 2.1 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_1 PF00078.27 CCD23648.1 - 0.0012 18.4 0.4 0.037 13.6 0.4 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 CCD23648.1 - 0.091 12.6 0.0 0.34 10.7 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain zf-CCHC PF00098.23 CCD23648.1 - 0.16 12.1 2.3 0.29 11.3 2.3 1.5 1 0 0 1 1 1 0 Zinc knuckle YceD PF02620.17 CCD23649.1 - 0.098 12.8 2.5 8 6.6 0.1 2.8 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD SAPS PF04499.15 CCD23650.1 - 2.2e-161 538.0 17.7 2.2e-161 538.0 17.7 2.7 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein DnaJ PF00226.31 CCD23651.1 - 2.6e-13 49.9 5.3 5.4e-13 48.9 5.3 1.6 1 0 0 1 1 1 1 DnaJ domain Adaptin_binding PF10199.9 CCD23653.1 - 1.5e-07 32.0 2.1 0.0053 17.4 0.2 2.4 1 1 1 2 2 2 2 Alpha and gamma adaptin binding protein p34 Hormone_recep PF00104.30 CCD23653.1 - 0.12 12.0 2.2 0.44 10.1 0.1 2.2 2 0 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor Peptidase_M20 PF01546.28 CCD23654.1 - 2.2e-32 112.5 0.0 3.4e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CCD23654.1 - 1.1e-11 44.7 0.0 1.8e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CCD23654.1 - 0.053 13.2 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Mito_carr PF00153.27 CCD23655.1 - 8.8e-43 144.2 9.0 2.2e-20 72.4 0.2 4.5 3 2 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CCD23655.1 - 0.0011 18.2 0.8 0.069 12.3 0.0 3.0 3 1 0 3 3 3 1 Gammaproteobacterial serine protease DUF5506 PF17611.2 CCD23655.1 - 0.0056 16.6 0.1 0.12 12.3 0.0 2.6 3 0 0 3 3 3 1 Family of unknown function (DUF5506) CUB PF00431.20 CCD23655.1 - 0.079 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 CUB domain APOBEC_C PF05240.14 CCD23656.1 - 0.012 15.5 0.1 0.03 14.3 0.1 1.7 1 0 0 1 1 1 0 APOBEC-like C-terminal domain ATP-synt_E_2 PF08112.11 CCD23656.1 - 0.57 10.5 11.0 0.15 12.4 1.5 3.4 3 0 0 3 3 3 0 ATP synthase epsilon subunit IBN_N PF03810.19 CCD23657.1 - 2.8e-09 36.8 3.4 6e-09 35.7 0.0 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain Ank PF00023.30 CCD23658.1 - 2.6e-11 43.4 0.1 0.00035 20.9 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CCD23658.1 - 3.9e-09 36.0 0.0 0.0033 17.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CCD23658.1 - 4.6e-09 36.4 0.0 0.00018 21.7 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCD23658.1 - 1.1e-07 32.3 0.0 1.8e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCD23658.1 - 0.0029 18.2 0.1 0.28 11.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) YjzC PF14168.6 CCD23658.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 YjzC-like protein DUF155 PF02582.14 CCD23659.1 - 2.4e-52 177.5 0.2 4e-52 176.9 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Brr6_like_C_C PF10104.9 CCD23660.1 - 6.4e-42 142.5 4.6 7.5e-42 142.3 4.6 1.0 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF2778 PF10908.8 CCD23660.1 - 0.029 14.7 0.0 0.048 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2778) S36_mt PF10937.8 CCD23661.1 - 7.5e-30 104.9 0.0 8.7e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Proteasome PF00227.26 CCD23662.1 - 6.1e-24 84.5 0.0 7.5e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit IFT81_CH PF18383.1 CCD23662.1 - 0.053 13.8 0.1 4.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Intraflagellar transport 81 calponin homology domain Adap_comp_sub PF00928.21 CCD23663.1 - 7.3e-09 35.4 0.5 1.2e-08 34.7 0.5 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CCD23663.1 - 1.7e-07 31.3 4.6 2.4e-07 30.8 1.9 2.3 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Ndc1_Nup PF09531.10 CCD23663.1 - 0.41 9.3 4.6 0.61 8.7 4.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2076 PF09849.9 CCD23663.1 - 0.65 10.0 9.9 1 9.3 9.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ppx-GppA PF02541.16 CCD23664.1 - 4.3e-57 193.7 0.0 5.8e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family CSN8_PSD8_EIF3K PF10075.9 CCD23665.1 - 6e-18 65.2 0.1 9e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 CCD23665.1 - 4e-07 29.7 0.1 5.3e-07 29.3 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP family Thymopoietin PF08198.11 CCD23665.1 - 0.02 14.5 0.1 0.098 12.3 0.0 2.0 2 0 0 2 2 2 0 Thymopoietin protein Hexokinase_2 PF03727.16 CCD23666.1 - 2.1e-78 263.0 0.0 2.9e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CCD23666.1 - 6e-68 228.7 0.0 1.7e-67 227.2 0.0 1.7 2 0 0 2 2 2 1 Hexokinase DUF2294 PF10057.9 CCD23666.1 - 0.0011 19.1 0.0 0.046 13.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2294) GST_N PF02798.20 CCD23667.1 - 6.3e-15 55.3 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CCD23667.1 - 5.5e-12 45.7 0.0 1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CCD23667.1 - 1.6e-07 31.6 0.0 3.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CCD23667.1 - 7.1e-05 22.9 0.1 0.00014 22.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CCD23667.1 - 0.0044 17.3 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CCD23667.1 - 0.044 13.8 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CCD23668.1 - 1.6e-13 50.8 0.0 8.6e-13 48.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CCD23668.1 - 5.6e-05 23.1 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CCD23668.1 - 0.036 14.5 0.0 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Sir1 PF11603.8 CCD23669.1 - 6e-34 117.1 0.3 2.4e-33 115.2 0.3 2.1 1 0 0 1 1 1 1 Regulatory protein Sir1 Helicase_C PF00271.31 CCD23669.1 - 0.00023 21.5 0.5 0.00069 19.9 0.5 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CENP-B_dimeris PF09026.10 CCD23669.1 - 0.14 12.6 4.6 0.28 11.6 4.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sir1 PF11603.8 CCD23670.1 - 1e-32 113.2 0.4 3.5e-32 111.4 0.4 2.0 1 0 0 1 1 1 1 Regulatory protein Sir1 Helicase_C PF00271.31 CCD23670.1 - 0.0016 18.7 0.2 0.0048 17.2 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CENP-B_dimeris PF09026.10 CCD23670.1 - 0.13 12.7 4.6 0.28 11.6 4.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pan3_PK PF18101.1 CCD23672.1 - 3.3e-52 176.1 0.1 6e-52 175.3 0.1 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain HIGH_NTase1 PF05636.11 CCD23672.1 - 0.0014 18.0 0.5 0.003 16.8 0.5 1.5 1 0 0 1 1 1 1 HIGH Nucleotidyl Transferase adh_short PF00106.25 CCD23673.1 - 1.2e-45 155.4 0.2 1.5e-45 155.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCD23673.1 - 1.6e-28 99.8 0.1 2e-28 99.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCD23673.1 - 1.7e-09 37.8 0.0 2.5e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CCD23673.1 - 0.0022 17.5 0.1 0.0035 16.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 CCD23673.1 - 0.024 14.9 0.1 0.051 13.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.15 CCD23673.1 - 0.044 12.9 0.0 0.067 12.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4848 PF16140.5 CCD23673.1 - 0.1 12.2 0.3 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4848) ADK PF00406.22 CCD23674.1 - 2.8e-48 163.8 0.0 3.5e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CCD23674.1 - 1.4e-38 132.4 0.0 1.9e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCD23674.1 - 6.2e-10 39.7 0.0 9.3e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CCD23674.1 - 6.4e-06 26.0 0.3 0.027 14.1 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 CCD23674.1 - 5.1e-05 23.5 0.0 0.00016 21.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CCD23674.1 - 0.0073 15.6 0.0 0.013 14.8 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin SRP54 PF00448.22 CCD23674.1 - 0.039 13.6 0.0 0.047 13.3 0.0 1.4 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Ploopntkinase3 PF18751.1 CCD23674.1 - 0.072 13.0 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 UPF0302 PF08864.10 CCD23675.1 - 0.0042 17.1 0.2 0.006 16.6 0.2 1.3 1 0 0 1 1 1 1 UPF0302 domain ETRAMP PF09716.10 CCD23675.1 - 0.0056 16.7 0.3 0.0075 16.3 0.3 1.2 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) HCO3_cotransp PF00955.21 CCD23675.1 - 0.039 12.8 0.9 0.036 12.9 0.9 1.0 1 0 0 1 1 1 0 HCO3- transporter family DUF1676 PF07898.13 CCD23675.1 - 0.045 13.8 0.1 0.055 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Orf78 PF06024.12 CCD23675.1 - 0.067 13.5 0.1 0.083 13.2 0.1 1.1 1 0 0 1 1 1 0 Orf78 (ac78) Consortin_C PF15281.6 CCD23675.1 - 0.072 13.1 0.0 0.09 12.8 0.0 1.1 1 0 0 1 1 1 0 Consortin C-terminus TPR_1 PF00515.28 CCD23677.1 - 1.5e-35 119.5 5.1 1.1e-05 25.0 0.1 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 CCD23677.1 - 2e-32 108.6 3.6 0.00077 19.4 0.0 9.9 10 0 0 10 10 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD23677.1 - 9.1e-24 83.5 9.4 4e-21 75.0 0.1 5.0 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CCD23677.1 - 1.6e-23 80.9 13.7 0.0004 20.4 0.0 9.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 CCD23677.1 - 1e-17 64.4 0.0 0.00032 21.1 0.0 6.1 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 CCD23677.1 - 7.3e-15 54.4 0.0 0.042 14.7 0.0 8.5 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCD23677.1 - 1.1e-14 53.9 3.8 6.5e-06 25.7 0.0 7.1 5 3 3 8 8 8 2 TPR repeat TPR_12 PF13424.6 CCD23677.1 - 1.1e-14 54.4 4.0 9.1e-06 25.9 0.2 7.7 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 CCD23677.1 - 9.9e-13 48.5 0.0 0.00037 21.1 0.0 5.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCD23677.1 - 1.2e-12 46.9 5.5 0.00017 21.4 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCD23677.1 - 5.5e-12 45.2 6.3 0.059 13.8 0.0 8.3 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 CCD23677.1 - 2.4e-10 40.4 2.5 1.3 9.8 0.0 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 CCD23677.1 - 3.2e-08 33.2 0.7 0.21 11.5 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CCD23677.1 - 1.4e-05 24.6 0.0 0.049 13.0 0.0 4.2 2 2 2 4 4 4 2 MalT-like TPR region TPR_15 PF13429.6 CCD23677.1 - 0.00023 20.5 0.7 0.5 9.5 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CCD23677.1 - 0.0019 18.3 0.0 0.024 14.8 0.0 3.0 4 0 0 4 4 2 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CCD23677.1 - 0.0036 17.3 5.8 5.6 7.0 0.0 3.9 2 2 1 3 3 3 1 Putative TPR-like repeat DUF4810 PF16068.5 CCD23677.1 - 0.045 14.3 0.2 12 6.6 0.0 3.4 2 1 2 4 4 3 0 Domain of unknown function (DUF4810) Fis1_TPR_C PF14853.6 CCD23677.1 - 0.055 13.5 10.1 0.8 9.8 0.3 5.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 CCD23677.1 - 0.076 13.4 0.1 6.1 7.2 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat SPO22 PF08631.10 CCD23677.1 - 0.16 11.5 11.8 0.19 11.2 2.7 3.4 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like DUF3439 PF11921.8 CCD23677.1 - 0.42 10.6 3.3 1 9.3 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RPN7 PF10602.9 CCD23677.1 - 1.3 8.7 5.7 2.5 7.8 1.5 3.3 3 2 2 5 5 5 0 26S proteasome subunit RPN7 WD40 PF00400.32 CCD23678.1 - 4.7e-22 77.9 8.0 2.1e-06 28.3 0.6 5.6 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD23678.1 - 1.7e-06 28.2 1.5 0.78 10.1 0.0 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCD23678.1 - 0.0015 17.2 0.4 0.16 10.6 0.0 2.7 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CCD23678.1 - 0.036 12.8 2.9 3.3 6.4 0.4 3.4 2 1 2 4 4 4 0 Nup133 N terminal like EF-hand_11 PF08976.11 CCD23678.1 - 0.082 13.8 0.1 0.29 12.0 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain Ank PF00023.30 CCD23679.1 - 1.1e-10 41.5 0.2 3.9e-05 23.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 CCD23679.1 - 3.2e-10 40.5 0.1 1.1e-09 38.8 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCD23679.1 - 3.4e-10 40.2 0.1 1.1e-09 38.7 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCD23679.1 - 1.5e-07 31.2 0.3 0.00053 20.2 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.24 CCD23679.1 - 7.2e-07 29.2 5.5 7.2e-07 29.2 5.5 3.5 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.6 CCD23679.1 - 0.0021 18.3 0.0 0.0021 18.3 0.0 3.8 3 1 1 4 4 4 1 Ankyrin repeats (many copies) RHD_dimer PF16179.5 CCD23679.1 - 0.025 14.6 0.6 0.14 12.2 0.0 2.6 2 0 0 2 2 2 0 Rel homology dimerisation domain DUF3417 PF11897.8 CCD23679.1 - 0.29 11.6 3.0 0.44 11.0 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) ORC5_C PF14630.6 CCD23680.1 - 8.7e-59 199.4 1.8 1.6e-58 198.5 1.8 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 CCD23680.1 - 1e-11 45.5 0.0 1.8e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain TRADD_N PF09034.10 CCD23680.1 - 0.025 14.6 0.3 0.14 12.3 0.1 2.2 1 1 1 2 2 2 0 TRADD, N-terminal domain AAA_22 PF13401.6 CCD23680.1 - 0.029 14.6 0.0 0.091 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain GDP_Man_Dehyd PF16363.5 CCD23680.1 - 0.046 13.1 0.1 0.079 12.3 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase AAA_14 PF13173.6 CCD23680.1 - 0.069 13.2 0.5 1.3 9.1 0.5 2.7 1 1 0 1 1 1 0 AAA domain DnaJ PF00226.31 CCD23681.1 - 5.8e-17 61.6 1.2 1.6e-16 60.2 1.2 1.8 1 0 0 1 1 1 1 DnaJ domain PPTA PF01239.22 CCD23682.1 - 1.7e-37 126.0 19.8 7e-08 32.0 0.2 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat UvrB_inter PF17757.1 CCD23682.1 - 0.025 14.8 0.0 0.6 10.3 0.0 2.4 2 0 0 2 2 2 0 UvrB interaction domain DUF1748 PF08520.10 CCD23683.1 - 4.1e-18 65.1 0.1 4.9e-18 64.8 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) FAM178 PF14816.6 CCD23683.1 - 0.054 12.5 0.0 0.067 12.1 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function, FAM178 WD40 PF00400.32 CCD23684.1 - 9.6e-12 45.2 0.1 0.0055 17.5 0.0 5.4 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD23684.1 - 6e-06 26.5 0.0 0.29 11.5 0.0 3.5 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 CCD23684.1 - 9.3e-06 25.1 0.0 0.00011 21.5 0.0 2.3 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller AAA_12 PF13087.6 CCD23685.1 - 3.7e-58 196.4 0.6 1.1e-57 194.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CCD23685.1 - 1.8e-52 178.7 2.8 2.1e-52 178.5 0.0 2.5 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CCD23685.1 - 9e-13 48.8 0.0 3.8e-12 46.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCD23685.1 - 1e-11 44.9 0.0 1.3e-07 31.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CCD23685.1 - 1.5e-07 31.4 0.2 0.35 10.6 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CCD23685.1 - 9.6e-06 25.3 0.5 3.8e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 CCD23685.1 - 1.8e-05 24.8 0.0 0.00011 22.2 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCD23685.1 - 0.00013 22.2 0.0 0.0017 18.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 CCD23685.1 - 0.00023 20.7 0.0 0.0029 17.1 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Helicase_RecD PF05127.14 CCD23685.1 - 0.00026 20.9 0.0 0.0039 17.1 0.0 2.7 3 0 0 3 3 2 1 Helicase DEAD PF00270.29 CCD23685.1 - 0.00095 19.0 0.2 0.025 14.4 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase PIF1 PF05970.14 CCD23685.1 - 0.002 17.3 0.1 0.35 10.0 0.0 2.5 2 0 0 2 2 2 1 PIF1-like helicase TrwB_AAD_bind PF10412.9 CCD23685.1 - 0.0048 15.9 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain IL2 PF00715.17 CCD23685.1 - 0.0099 15.8 0.2 0.028 14.4 0.2 1.7 1 0 0 1 1 1 1 Interleukin 2 AAA PF00004.29 CCD23685.1 - 0.011 16.1 0.1 0.058 13.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CCD23685.1 - 0.011 15.4 0.0 0.052 13.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 CCD23685.1 - 0.022 14.6 0.2 0.5 10.3 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 CCD23685.1 - 0.024 14.4 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 CCD23685.1 - 0.025 13.8 0.0 0.078 12.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 CCD23685.1 - 0.03 13.4 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF853 PF05872.12 CCD23685.1 - 0.034 12.7 0.0 0.053 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_16 PF13191.6 CCD23685.1 - 0.045 14.1 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 CCD23685.1 - 0.067 13.2 0.2 0.24 11.4 0.2 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.6 CCD23685.1 - 0.072 13.1 0.1 1.4 8.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 CCD23685.1 - 0.084 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_33 PF13671.6 CCD23685.1 - 0.17 12.0 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mt_ATP-synt_D PF05873.12 CCD23686.1 - 4.9e-18 65.4 4.2 5.9e-18 65.2 4.2 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF4201 PF13870.6 CCD23686.1 - 0.0047 16.7 2.4 0.051 13.3 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) DUF1104 PF06518.11 CCD23686.1 - 0.016 15.5 3.7 0.028 14.8 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Herpes_UL47 PF03362.13 CCD23686.1 - 0.056 12.2 0.1 0.075 11.8 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL47 protein PK_C PF02887.16 CCD23686.1 - 0.058 13.6 0.1 0.12 12.6 0.1 1.5 1 1 0 1 1 1 0 Pyruvate kinase, alpha/beta domain Pet20 PF08692.10 CCD23686.1 - 0.078 13.7 0.6 0.11 13.2 0.5 1.3 1 1 0 1 1 1 0 Mitochondrial protein Pet20 Vac_Fusion PF02346.16 CCD23686.1 - 0.089 12.4 0.1 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 U-box PF04564.15 CCD23686.1 - 0.13 12.5 0.4 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 U-box domain DUF2408 PF10303.9 CCD23686.1 - 0.74 10.4 5.0 2.6 8.6 5.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF948 PF06103.11 CCD23686.1 - 0.9 9.8 3.8 0.59 10.4 1.1 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FlxA PF14282.6 CCD23686.1 - 6.1 6.9 8.1 11 6.1 2.7 2.3 1 1 1 2 2 2 0 FlxA-like protein Fungal_trans PF04082.18 CCD23687.1 - 7.7e-15 54.6 2.5 7.7e-15 54.6 2.5 3.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD23687.1 - 1.4e-09 37.9 11.4 2.7e-09 37.0 11.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ARPC4 PF05856.12 CCD23688.1 - 4.2e-74 247.7 3.7 4.7e-74 247.5 3.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Peptidase_S24 PF00717.23 CCD23689.1 - 1.9e-08 34.1 0.0 3e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase S24-like Cry1Ac_D5 PF17997.1 CCD23689.1 - 0.021 14.7 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Insecticidal delta-endotoxin CryIA(c) domain 5 CCB2_CCB4 PF11152.8 CCD23689.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 Ydc2-catalyt PF09159.10 CCD23690.1 - 5.1e-44 151.1 9.5 1.3e-43 149.7 9.5 1.6 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Secretin_N_2 PF07655.13 CCD23690.1 - 0.16 12.5 8.5 0.5 10.9 8.5 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain Pox_A22 PF04848.13 CCD23690.1 - 0.55 10.3 3.8 6.6 6.8 0.0 3.0 4 0 0 4 4 4 0 Poxvirus A22 protein Presenilin PF01080.17 CCD23690.1 - 0.57 8.9 2.3 0.52 9.0 1.2 1.4 2 0 0 2 2 2 0 Presenilin DUF1673 PF07895.11 CCD23690.1 - 1.5 8.5 6.7 3.2 7.4 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) MIP PF00230.20 CCD23691.1 - 5.2e-43 147.4 12.2 6.4e-43 147.1 12.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein Deltameth_res PF16020.5 CCD23691.1 - 0.37 10.7 2.4 1.9 8.4 0.0 2.8 2 1 1 3 3 3 0 Deltamethrin resistance PRA1 PF03208.19 CCD23691.1 - 5.6 6.6 6.4 5.1 6.7 4.4 2.0 1 1 1 2 2 2 0 PRA1 family protein Flavoprotein PF02441.19 CCD23692.1 - 1.5e-50 171.0 0.9 7.2e-50 168.8 0.1 2.1 2 0 0 2 2 2 1 Flavoprotein Cyto_heme_lyase PF01265.17 CCD23693.1 - 1.6e-29 103.5 17.4 3.9e-27 95.6 17.4 2.2 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase SgrR_N PF12793.7 CCD23693.1 - 0.046 13.9 0.1 0.087 13.0 0.1 1.3 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term ParBc PF02195.18 CCD23694.1 - 1.4e-14 54.1 0.0 1.7e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain Ldh_1_C PF02866.18 CCD23695.1 - 2.2e-53 180.6 0.1 4.4e-53 179.6 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CCD23695.1 - 3.7e-43 147.0 0.0 5.2e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CCD23695.1 - 0.00035 19.7 0.0 0.00054 19.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CCD23695.1 - 0.014 15.8 0.2 0.09 13.2 0.0 2.4 4 0 0 4 4 4 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CCD23695.1 - 0.097 12.0 0.2 0.47 9.8 0.0 2.3 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain zf-CHY PF05495.12 CCD23696.1 - 6.9e-10 39.3 15.5 1.2e-09 38.5 15.5 1.4 1 0 0 1 1 1 1 CHY zinc finger Ank_4 PF13637.6 CCD23697.1 - 3.8e-18 65.6 6.1 3.1e-07 30.8 0.8 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCD23697.1 - 5.5e-18 65.3 7.0 8.4e-08 32.7 0.9 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 CCD23697.1 - 1.3e-10 41.2 8.7 0.0089 16.4 0.3 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CCD23697.1 - 2.3e-10 39.8 8.2 0.00077 19.7 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CCD23697.1 - 4.4e-07 30.0 3.7 0.028 14.7 0.1 3.7 2 2 2 4 4 4 3 Ankyrin repeats (many copies) EF1G PF00647.19 CCD23698.1 - 1.9e-47 159.7 0.1 4.4e-47 158.6 0.1 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CCD23698.1 - 3.9e-13 49.4 0.1 3.9e-13 49.4 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CCD23698.1 - 1.5e-10 41.2 0.4 4.6e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CCD23698.1 - 1.2e-05 25.3 0.3 2.5e-05 24.2 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CCD23698.1 - 0.0034 17.6 0.1 0.0034 17.6 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain BOP1NT PF08145.12 CCD23700.1 - 5.9e-102 341.0 5.9 5.9e-102 341.0 5.9 1.8 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 CCD23700.1 - 2e-22 79.0 8.5 4.1e-09 36.9 0.2 6.8 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD23700.1 - 4.6e-08 33.3 0.6 0.0016 18.7 0.0 4.9 4 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain GAF_2 PF13185.6 CCD23701.1 - 5.7e-06 26.7 0.0 7.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 CCD23701.1 - 0.00032 21.3 0.0 0.00036 21.2 0.0 1.2 1 0 0 1 1 1 1 GAF domain AlaDh_PNT_C PF01262.21 CCD23701.1 - 0.18 11.1 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LptF_LptG PF03739.14 CCD23702.1 - 0.22 10.3 0.5 0.41 9.5 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG UPF0449 PF15136.6 CCD23702.1 - 3.4 8.2 7.2 2.2 8.8 3.7 2.5 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Spc24 PF08286.11 CCD23702.1 - 4.1 7.7 9.0 0.15 12.4 1.7 2.4 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 HSP70 PF00012.20 CCD23703.1 - 3.8e-54 183.9 5.8 3.8e-54 183.9 5.8 2.2 2 0 0 2 2 2 1 Hsp70 protein RRM_1 PF00076.22 CCD23704.1 - 3.8e-05 23.4 0.0 0.012 15.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4448 PF14610.6 CCD23706.1 - 3.3e-55 186.8 0.5 5e-55 186.2 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Nucleoside_tran PF01733.18 CCD23706.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Nucleoside transporter PIG-Y PF15159.6 CCD23706.1 - 5.4 8.0 6.1 0.81 10.6 0.8 2.4 3 0 0 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Sen15 PF09631.10 CCD23707.1 - 4.1e-29 100.8 0.1 4.7e-29 100.6 0.1 1.0 1 0 0 1 1 1 1 Sen15 protein SDH_C PF18317.1 CCD23707.1 - 0.021 14.6 0.0 0.46 10.3 0.0 2.2 2 0 0 2 2 2 0 Shikimate 5'-dehydrogenase C-terminal domain HA2 PF04408.23 CCD23708.1 - 4.7e-20 71.9 0.0 1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CCD23708.1 - 5.3e-14 52.4 0.0 1.5e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CCD23708.1 - 4.2e-10 39.9 0.1 1.9e-09 37.8 0.0 2.2 3 0 0 3 3 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCD23708.1 - 2.8e-09 37.0 0.0 5.4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCD23708.1 - 8.4e-06 26.1 0.1 2.5e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCD23708.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCD23708.1 - 0.0017 18.7 0.0 0.004 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CCD23708.1 - 0.007 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CCD23708.1 - 0.011 15.4 0.0 0.065 12.9 0.0 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 CCD23708.1 - 0.011 15.4 0.2 0.032 14.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CCD23708.1 - 0.015 15.8 2.6 0.017 15.6 0.0 2.2 1 1 1 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CCD23708.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase PhoH PF02562.16 CCD23708.1 - 0.069 12.6 0.0 0.4 10.1 0.0 2.2 3 0 0 3 3 3 0 PhoH-like protein ABC_tran PF00005.27 CCD23708.1 - 0.16 12.4 2.3 0.31 11.6 0.1 2.5 2 1 1 3 3 3 0 ABC transporter Kinesin PF00225.23 CCD23709.1 - 8.4e-44 149.8 7.1 8.4e-44 149.8 7.1 2.3 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CCD23709.1 - 9.4e-10 38.6 2.5 3.9e-09 36.6 2.5 2.1 1 1 0 1 1 1 1 Microtubule binding Herpes_UL51 PF04540.13 CCD23709.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus UL51 protein V-ATPase_C PF03223.15 CCD23710.1 - 5.2e-120 401.2 4.2 5.8e-120 401.1 4.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C NUC130_3NT PF08158.12 CCD23710.1 - 0.00067 19.9 0.2 0.96 9.8 0.0 2.6 2 0 0 2 2 2 2 NUC130/3NT domain Nucleoporin_FG PF13634.6 CCD23711.1 - 1.8e-51 172.9 327.7 4.5e-11 43.4 38.3 11.5 1 1 10 11 11 11 9 Nucleoporin FG repeat region Nucleoporin2 PF04096.14 CCD23711.1 - 1.1e-33 116.4 0.0 2.1e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase SRF-TF PF00319.18 CCD23712.1 - 1.9e-21 75.2 0.2 3.3e-21 74.5 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) NDK PF00334.19 CCD23713.1 - 1.9e-56 189.8 0.0 2.2e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Bap31 PF05529.12 CCD23714.1 - 9.9e-25 87.0 0.6 1.4e-24 86.5 0.6 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Anoctamin PF04547.12 CCD23714.1 - 0.0084 15.0 0.0 0.0094 14.8 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel LapA_dom PF06305.11 CCD23714.1 - 0.03 14.1 0.2 4.1 7.3 0.0 3.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF5082 PF16888.5 CCD23714.1 - 0.056 13.7 0.7 0.11 12.7 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) CorA PF01544.18 CCD23715.1 - 4.3e-39 134.6 4.9 5.4e-22 78.4 0.6 3.4 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein zf-C2H2_4 PF13894.6 CCD23717.1 - 4.3e-07 30.2 13.5 0.0037 18.0 2.0 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CCD23717.1 - 9e-06 25.9 25.6 7.4e-05 23.0 4.0 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCD23717.1 - 3.6e-05 24.0 18.1 0.00064 20.0 3.4 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CCD23717.1 - 0.0042 17.3 10.1 0.3 11.4 1.0 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 CCD23717.1 - 2 8.4 5.4 12 6.0 0.5 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2HE PF16278.5 CCD23717.1 - 3 8.4 12.1 0.52 10.8 0.9 3.7 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Pkinase PF00069.25 CCD23718.1 - 9.2e-34 117.0 8.0 9.5e-27 94.0 0.1 3.6 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23718.1 - 2e-17 63.3 0.3 4.6e-13 49.1 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 CCD23718.1 - 0.00029 20.3 0.0 0.012 14.9 0.0 2.8 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 CCD23718.1 - 0.0082 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Actin PF00022.19 CCD23719.1 - 2.6e-17 62.5 0.0 1.4e-15 56.9 0.0 2.8 2 1 0 2 2 2 1 Actin FtsA PF14450.6 CCD23719.1 - 0.031 14.7 0.9 0.2 12.1 0.9 2.4 1 1 0 1 1 1 0 Cell division protein FtsA Seryl_tRNA_N PF02403.22 CCD23719.1 - 0.69 10.2 4.6 0.17 12.1 0.6 2.0 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Histone PF00125.24 CCD23720.1 - 6.2e-36 123.7 6.7 1.1e-35 122.8 6.7 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Eisosome1 PF12757.7 CCD23721.1 - 2.4e-23 82.8 0.4 2.4e-23 82.8 0.4 4.7 4 0 0 4 4 4 1 Eisosome protein 1 Frag1 PF10277.9 CCD23722.1 - 2.8e-80 269.0 25.5 3.3e-80 268.7 25.5 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Chorion_2 PF03964.15 CCD23722.1 - 0.067 14.0 0.6 0.13 13.1 0.6 1.4 1 0 0 1 1 1 0 Chorion family 2 DUF3611 PF12263.8 CCD23722.1 - 0.15 11.9 7.3 0.028 14.3 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) CitMHS PF03600.16 CCD23722.1 - 1.9 7.6 5.9 2.7 7.1 5.9 1.4 1 0 0 1 1 1 0 Citrate transporter CUE PF02845.16 CCD23723.1 - 1.8e-05 24.4 0.0 3.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 CUE domain UPF0203 PF05254.12 CCD23724.1 - 2.2e-27 95.1 3.7 3e-27 94.7 3.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 CCD23724.1 - 0.00065 19.9 0.4 0.0013 18.9 0.4 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.10 CCD23724.1 - 0.022 14.7 2.4 0.27 11.3 1.0 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DASH_Ask1 PF08655.10 CCD23725.1 - 7.4e-28 96.2 1.7 1.5e-27 95.2 1.7 1.6 1 0 0 1 1 1 1 DASH complex subunit Ask1 F_bP_aldolase PF01116.20 CCD23726.1 - 1.3e-87 293.8 0.1 1.5e-87 293.6 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II BLI1 PF17324.2 CCD23727.1 - 9.7e-22 77.7 1.0 1e-21 77.6 1.0 1.1 1 0 0 1 1 1 1 BLOC-1 interactor 1 DUF2347 PF09804.9 CCD23728.1 - 2.8e-69 233.9 1.2 3.8e-69 233.4 1.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 CCD23728.1 - 1.5e-10 40.4 0.9 2.2e-09 36.5 0.9 2.6 1 1 0 1 1 1 1 Transport protein Avl9 DUF4484 PF14831.6 CCD23728.1 - 3.3e-09 37.1 0.1 8.2e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4484) SPA PF08616.10 CCD23728.1 - 2.5e-08 33.8 0.0 6.4e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Glyco_hydro_76 PF03663.14 CCD23729.1 - 1.3e-160 534.9 22.0 1.5e-160 534.7 22.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 zf-C2H2 PF00096.26 CCD23730.1 - 0.0015 18.9 2.9 0.0015 18.9 2.9 3.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD23730.1 - 0.014 16.2 15.9 0.061 14.2 1.4 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CCD23730.1 - 0.034 13.9 0.8 5 7.0 0.0 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type UL45 PF05473.12 CCD23730.1 - 0.052 13.2 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like zf-H2C2_2 PF13465.6 CCD23730.1 - 0.064 13.7 1.1 0.064 13.7 1.1 3.6 3 0 0 3 3 3 0 Zinc-finger double domain PyrI_C PF02748.15 CCD23730.1 - 0.33 10.9 0.1 0.33 10.9 0.1 2.6 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HE PF16278.5 CCD23730.1 - 0.54 10.7 4.8 5.3 7.6 0.1 3.3 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Apis_Csd PF11671.8 CCD23730.1 - 1.7 8.7 17.1 0.86 9.6 4.3 3.1 2 0 0 2 2 2 0 Complementary sex determiner protein PGAP1 PF07819.13 CCD23731.1 - 1.3e-07 31.6 0.0 2.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 CCD23731.1 - 3.1e-07 30.1 0.1 7.5e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CCD23731.1 - 6.5e-06 26.2 0.0 5.4e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 CCD23731.1 - 3.5e-05 23.3 0.1 0.00084 18.7 0.0 2.7 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 CCD23731.1 - 4e-05 23.4 0.0 0.00036 20.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold LCAT PF02450.15 CCD23731.1 - 0.0063 15.7 0.5 0.0091 15.2 0.0 1.6 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase adh_short PF00106.25 CCD23732.1 - 2e-29 102.5 0.4 5.6e-21 74.9 0.2 2.8 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CCD23732.1 - 1.8e-16 60.4 0.4 1.1e-12 48.0 0.1 2.9 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CCD23732.1 - 0.00054 19.5 0.0 0.014 14.9 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CCD23732.1 - 0.014 15.3 0.5 0.22 11.4 0.5 2.3 1 1 0 1 1 1 0 KR domain TCTP PF00838.17 CCD23733.1 - 1.1e-72 243.8 1.4 1.2e-72 243.6 1.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein TFIIA_gamma_N PF02268.16 CCD23734.1 - 1.7e-22 79.1 0.2 2.3e-22 78.7 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 CCD23734.1 - 8.7e-22 77.0 7.2 1.9e-21 75.9 7.2 1.6 1 1 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Transketolase_C PF02780.20 CCD23734.1 - 0.15 12.0 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Transketolase, C-terminal domain DWNN PF08783.11 CCD23735.1 - 9.7e-32 109.1 2.7 1.7e-31 108.3 0.2 2.3 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 CCD23735.1 - 1e-07 31.6 7.5 1.4e-07 31.2 5.3 2.1 2 0 0 2 2 2 1 Zinc knuckle U-box PF04564.15 CCD23735.1 - 1.8e-06 28.1 0.0 5.4e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 CCD23735.1 - 0.00065 19.5 0.7 0.0018 18.1 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-CCHC_5 PF14787.6 CCD23735.1 - 0.0014 18.3 1.8 0.012 15.4 0.2 2.6 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 CCD23735.1 - 0.0016 18.4 2.2 0.0016 18.4 2.2 2.3 2 0 0 2 2 2 1 Zinc knuckle DUF1610 PF07754.11 CCD23735.1 - 0.033 14.1 1.1 0.09 12.8 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Rubredoxin PF00301.20 CCD23735.1 - 0.034 14.2 4.7 1.1 9.3 0.1 3.1 3 0 0 3 3 3 0 Rubredoxin zf-DNL PF05180.12 CCD23735.1 - 0.045 13.7 2.4 0.045 13.7 0.4 2.0 2 0 0 2 2 2 0 DNL zinc finger SNN_cytoplasm PF09051.10 CCD23735.1 - 0.11 12.4 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Stannin cytoplasmic zf-CCHC_3 PF13917.6 CCD23735.1 - 0.11 12.5 1.3 0.2 11.6 0.2 2.1 2 0 0 2 2 2 0 Zinc knuckle TF_Zn_Ribbon PF08271.12 CCD23735.1 - 0.18 11.4 0.1 0.18 11.4 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding INCA1 PF15142.6 CCD23735.1 - 1.7 8.7 6.9 0.47 10.5 0.1 2.6 3 0 0 3 3 3 0 INCA1 zf-C3HC4_2 PF13923.6 CCD23735.1 - 6.9 6.6 6.4 0.93 9.4 0.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPT PF03151.16 CCD23736.1 - 1.3e-16 60.9 23.4 4.5e-09 36.1 3.7 3.1 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 CCD23736.1 - 3.4e-06 27.3 31.9 0.00027 21.1 3.4 4.1 4 1 0 4 4 4 3 EamA-like transporter family PUNUT PF16913.5 CCD23736.1 - 5e-06 26.0 1.1 5e-06 26.0 1.1 2.4 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport EmrE PF13536.6 CCD23736.1 - 0.012 15.2 8.1 0.026 14.1 0.7 2.4 2 0 0 2 2 2 0 Putative multidrug resistance efflux transporter TMEM234 PF10639.9 CCD23736.1 - 0.031 14.3 10.6 1.2 9.2 0.9 3.2 3 0 0 3 3 3 0 Putative transmembrane family 234 CoA_binding_3 PF13727.6 CCD23736.1 - 0.054 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 CoA-binding domain TMEMspv1-c74-12 PF11044.8 CCD23736.1 - 0.099 12.6 0.3 0.099 12.6 0.3 4.2 6 0 0 6 6 6 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein CGI-121 PF08617.10 CCD23738.1 - 1.2e-44 152.3 2.0 1.3e-44 152.2 2.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DUF2294 PF10057.9 CCD23738.1 - 0.026 14.6 0.4 1.2 9.2 0.0 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2294) A_deaminase PF00962.22 CCD23739.1 - 9e-132 439.4 0.0 1.3e-131 438.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase MSC PF09402.10 CCD23740.1 - 3.8e-108 361.9 3.2 3.8e-108 361.9 3.2 3.1 4 0 0 4 4 4 1 Man1-Src1p-C-terminal domain HeH PF12949.7 CCD23740.1 - 3.6e-11 42.6 1.4 1.9e-10 40.3 1.4 2.3 1 0 0 1 1 1 1 HeH/LEM domain PRESAN PF09687.10 CCD23740.1 - 0.044 14.3 0.2 0.044 14.3 0.2 4.1 5 0 0 5 5 5 0 Plasmodium RESA N-terminal Rad52_Rad22 PF04098.15 CCD23741.1 - 8.8e-56 188.1 0.0 1.5e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Ndc1_Nup PF09531.10 CCD23742.1 - 2.3e-96 323.9 13.8 3e-96 323.5 13.8 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup HIG_1_N PF04588.13 CCD23743.1 - 1.3e-15 57.3 1.6 1.8e-15 56.9 1.6 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Phage_prot_Gp6 PF05133.14 CCD23743.1 - 0.012 14.8 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like M PF02370.16 CCD23743.1 - 0.55 11.0 0.1 0.55 11.0 0.1 3.4 4 0 0 4 4 4 0 M protein repeat ubiquitin PF00240.23 CCD23744.1 - 0.0063 16.2 0.0 0.022 14.5 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family Tctex-1 PF03645.13 CCD23744.1 - 0.028 14.6 0.2 0.59 10.4 0.0 3.2 2 2 0 2 2 2 0 Tctex-1 family TUG-UBL1 PF11470.8 CCD23744.1 - 0.12 12.6 0.0 0.55 10.5 0.0 2.2 1 0 0 1 1 1 0 TUG ubiquitin-like domain AhpC-TSA PF00578.21 CCD23745.1 - 3.7e-34 117.3 0.0 8.2e-34 116.2 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CCD23745.1 - 8.6e-18 64.5 0.0 1.7e-17 63.5 0.0 1.4 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.9 CCD23745.1 - 2.2e-10 40.2 0.1 5.3e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CCD23745.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC Homeodomain PF00046.29 CCD23746.1 - 2.4e-16 59.3 4.6 8.6e-16 57.5 4.6 2.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CCD23746.1 - 0.013 15.4 0.8 0.04 13.8 0.1 2.2 2 0 0 2 2 2 0 Homeobox KN domain Ribosomal_S13 PF00416.22 CCD23747.1 - 2.6e-57 192.7 2.7 3e-57 192.5 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CCD23747.1 - 0.0042 15.9 0.0 0.0059 15.4 0.0 1.2 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_L4 PF00573.22 CCD23748.1 - 1.3e-46 158.7 0.0 1.6e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S17e PF00833.18 CCD23749.1 - 2.7e-56 188.7 0.3 3.2e-56 188.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal S17 Nse5 PF08691.10 CCD23750.1 - 2.3e-122 409.3 18.2 2.7e-122 409.1 18.2 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Pribosyltran PF00156.27 CCD23751.1 - 3.1e-16 59.3 0.0 4e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CCD23751.1 - 0.0064 15.9 0.0 0.0084 15.6 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase UDG PF03167.19 CCD23752.1 - 2.7e-24 85.9 0.1 5.3e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF2357 PF09823.9 CCD23752.1 - 0.042 13.1 0.4 0.07 12.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) VP4_2 PF08935.10 CCD23753.1 - 4.7 7.9 10.3 0.35 11.5 4.9 1.9 2 0 0 2 2 2 0 Viral protein VP4 subunit OST3_OST6 PF04756.13 CCD23754.1 - 5.9e-68 229.4 5.1 6.8e-68 229.2 5.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 CCD23754.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin NOB1_Zn_bind PF08772.11 CCD23754.1 - 0.033 14.3 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Sbt_1 PF05982.12 CCD23754.1 - 0.045 13.0 0.2 0.069 12.4 0.2 1.4 1 0 0 1 1 1 0 Na+-dependent bicarbonate transporter superfamily DUF5592 PF17332.2 CCD23754.1 - 0.3 11.7 5.3 0.17 12.5 1.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5592) EamA PF00892.20 CCD23755.1 - 1.2e-10 41.7 36.3 2.3e-06 27.8 13.3 3.1 3 0 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 CCD23755.1 - 0.0022 17.6 9.6 0.0022 17.6 9.6 1.9 2 0 0 2 2 2 1 Solute carrier family 35 DUF3955 PF13127.6 CCD23755.1 - 0.0057 16.5 3.4 0.0057 16.5 3.4 5.0 6 0 0 6 6 6 1 Protein of unknown function (DUF3955) TPT PF03151.16 CCD23755.1 - 0.0092 15.4 13.2 0.029 13.7 2.7 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family PUNUT PF16913.5 CCD23755.1 - 0.16 11.1 13.4 0.27 10.4 6.1 2.5 2 1 0 2 2 2 0 Purine nucleobase transmembrane transport FeoB_C PF07664.12 CCD23755.1 - 1.9 8.3 5.6 8 6.2 0.7 3.3 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus Phage_holin_4_1 PF05105.12 CCD23755.1 - 7.2 6.8 12.7 0.32 11.2 0.5 3.3 3 1 0 3 3 3 0 Bacteriophage holin family RRM_1 PF00076.22 CCD23756.1 - 0.07 13.0 0.6 2.5 8.0 0.1 2.4 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 CCD23757.1 - 6e-36 124.9 0.1 1.4e-35 123.7 0.1 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CCD23757.1 - 1.6e-18 66.9 0.5 3.3e-18 65.8 0.5 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Methyltransf_11 PF08241.12 CCD23758.1 - 3.9e-11 43.5 0.0 7e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCD23758.1 - 1.3e-08 35.5 0.0 2.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCD23758.1 - 4e-05 23.5 0.1 6.2e-05 22.8 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCD23758.1 - 5.9e-05 23.7 0.1 5.9e-05 23.7 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 CCD23758.1 - 0.013 14.5 1.0 0.019 13.9 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) Atrophin-1 PF03154.15 CCD23758.1 - 5.6 5.1 5.4 7.2 4.8 5.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family UBX PF00789.20 CCD23759.1 - 9.1e-14 51.4 0.1 1.2e-05 25.4 0.0 3.5 3 0 0 3 3 3 2 UBX domain UBA_4 PF14555.6 CCD23759.1 - 8e-12 44.8 3.8 2.9e-11 43.0 0.1 2.8 3 0 0 3 3 3 1 UBA-like domain EMP24_GP25L PF01105.24 CCD23760.1 - 8.1e-44 149.7 0.0 9.1e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 CCD23760.1 - 0.0087 14.3 1.2 0.011 13.9 1.2 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DASH_Dad2 PF08654.10 CCD23760.1 - 0.032 14.7 0.0 0.052 14.0 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad2 Takusan PF04822.13 CCD23760.1 - 0.094 12.6 1.5 0.17 11.8 1.5 1.4 1 0 0 1 1 1 0 Takusan Rad33 PF08730.10 CCD23761.1 - 4.6e-09 36.5 5.0 1.1e-06 28.7 0.8 2.1 1 1 1 2 2 2 2 Rad33 Spt5_N PF11942.8 CCD23762.1 - 7.2e-21 75.0 10.8 7.2e-21 75.0 10.8 3.4 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 CCD23762.1 - 8.3e-21 73.7 0.0 2.6e-20 72.1 0.0 1.9 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 CCD23762.1 - 1.5e-16 59.7 10.3 0.00021 21.2 0.1 4.7 4 0 0 4 4 4 4 KOW motif CTD PF12815.7 CCD23762.1 - 0.00048 20.6 28.3 0.00048 20.6 28.3 3.7 1 1 1 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF3912 PF13051.6 CCD23762.1 - 0.00079 19.6 0.7 0.33 11.2 0.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3912) DUF150_C PF17384.2 CCD23762.1 - 0.0041 17.2 0.7 0.77 9.9 0.6 2.7 2 0 0 2 2 2 1 RimP C-terminal SH3 domain Myosin_N PF02736.19 CCD23762.1 - 0.048 13.5 1.8 0.13 12.1 0.3 2.7 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain BUD22 PF09073.10 CCD23762.1 - 2.3 7.4 39.4 3.9 6.7 39.4 1.3 1 0 0 1 1 1 0 BUD22 Nucleo_P87 PF07267.11 CCD23762.1 - 4.5 6.0 24.4 9.2 5.0 24.4 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SDA1 PF05285.12 CCD23762.1 - 9.6 5.5 40.3 22 4.3 40.3 1.6 1 0 0 1 1 1 0 SDA1 Ribosomal_L33 PF00471.20 CCD23763.1 - 0.00071 20.0 0.0 0.0016 18.8 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L33 eIF3g PF12353.8 CCD23764.1 - 8.9e-41 139.2 1.5 1.3e-40 138.7 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 CCD23764.1 - 4.3e-12 45.7 0.0 8e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 CCD23764.1 - 0.22 11.9 1.9 0.39 11.1 0.2 2.2 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 PX PF00787.24 CCD23765.1 - 1.4e-14 54.0 1.7 8.9e-14 51.4 0.1 2.7 2 0 0 2 2 2 1 PX domain DUF19 PF01579.18 CCD23765.1 - 0.019 14.8 1.5 0.054 13.3 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF19) CLZ PF16526.5 CCD23765.1 - 0.11 12.8 7.1 0.83 10.1 0.9 3.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sterol_MT_C PF08498.10 CCD23766.1 - 1.6e-27 95.6 1.0 2.5e-27 95.0 1.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 CCD23766.1 - 4e-21 75.4 0.1 7.9e-21 74.4 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCD23766.1 - 1.6e-19 70.3 0.0 2.9e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCD23766.1 - 1.5e-17 64.1 0.0 3e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCD23766.1 - 9.9e-13 48.2 0.0 1.7e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CCD23766.1 - 1.5e-12 47.4 0.4 2e-12 47.0 0.4 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CCD23766.1 - 1.8e-12 47.9 0.0 4.6e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CCD23766.1 - 5.9e-09 35.6 0.0 8.9e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 CCD23766.1 - 0.00018 21.2 0.3 0.00051 19.6 0.2 1.7 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 CCD23766.1 - 0.0026 17.5 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 CCD23766.1 - 0.0031 16.7 0.9 0.0046 16.1 0.2 1.6 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_32 PF13679.6 CCD23766.1 - 0.0075 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CCD23766.1 - 0.0087 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 CCD23766.1 - 0.0089 17.0 0.0 0.02 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CCD23766.1 - 0.022 14.2 0.0 0.083 12.3 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase MetW PF07021.12 CCD23766.1 - 0.039 13.6 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW UPF0020 PF01170.18 CCD23766.1 - 0.044 13.5 0.1 0.26 10.9 0.0 2.2 1 1 2 3 3 3 0 Putative RNA methylase family UPF0020 MTS PF05175.14 CCD23766.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 CCD23766.1 - 0.16 11.8 0.0 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase PAP1 PF08601.10 CCD23767.1 - 5.8e-12 46.0 25.1 5.8e-12 46.0 25.1 5.5 1 1 2 4 4 4 1 Transcription factor PAP1 bZIP_1 PF00170.21 CCD23767.1 - 5.4e-06 26.4 14.9 2e-05 24.6 14.8 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CCD23767.1 - 0.013 15.6 14.9 0.041 14.0 14.6 2.2 1 1 0 1 1 1 0 Basic region leucine zipper Ribosomal_L11_N PF03946.14 CCD23770.1 - 1.4e-21 76.0 1.4 1.9e-21 75.6 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CCD23770.1 - 9.8e-17 61.2 1.3 1.9e-16 60.3 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Mak10 PF04112.13 CCD23771.1 - 1.1e-43 148.7 0.2 1.1e-43 148.7 0.2 2.1 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase HTH_57 PF18679.1 CCD23771.1 - 0.017 15.4 0.2 1.1 9.7 0.0 2.8 2 0 0 2 2 2 0 ThcOx helix turn helix domain DUF3019 PF11456.8 CCD23771.1 - 0.022 15.3 0.8 0.056 13.9 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3019) AFG1_ATPase PF03969.16 CCD23772.1 - 8.6e-78 261.7 0.0 2e-55 188.1 0.0 3.1 2 1 1 3 3 3 3 AFG1-like ATPase AAA PF00004.29 CCD23772.1 - 0.0001 22.7 0.0 0.00031 21.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 CCD23772.1 - 0.00025 21.0 0.0 0.00062 19.8 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 CCD23772.1 - 0.00046 20.6 0.1 0.028 14.8 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCD23772.1 - 0.044 14.1 0.1 0.18 12.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CCD23772.1 - 0.052 13.6 0.0 0.27 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 CCD23772.1 - 0.052 13.4 0.1 0.094 12.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein RNA_helicase PF00910.22 CCD23772.1 - 0.053 13.9 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 CCD23772.1 - 0.067 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF573 PF04504.14 CCD23772.1 - 0.62 10.8 5.2 0.99 10.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Ribosomal_L2_C PF03947.18 CCD23773.1 - 6.1e-52 175.1 2.8 1.3e-51 174.0 2.8 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CCD23773.1 - 1.2e-22 79.6 0.2 4.2e-22 77.9 0.1 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain EMC1_C PF07774.13 CCD23773.1 - 0.24 11.0 2.5 0.35 10.5 2.5 1.2 1 0 0 1 1 1 0 ER membrane protein complex subunit 1, C-terminal Carn_acyltransf PF00755.20 CCD23774.1 - 1.1e-175 585.6 4.6 1.4e-175 585.4 4.6 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SR-25 PF10500.9 CCD23774.1 - 0.058 13.0 7.7 0.042 13.5 5.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ADH_zinc_N_2 PF13602.6 CCD23775.1 - 1.2e-11 45.8 0.0 2.1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CCD23775.1 - 2.6e-06 27.5 0.0 4.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 CCD23775.1 - 0.0019 18.0 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) LDcluster4 PF18306.1 CCD23775.1 - 0.032 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 SLOG cluster4 family PINIT PF14324.6 CCD23776.1 - 7e-33 114.0 0.5 7e-33 114.0 0.5 3.1 3 0 0 3 3 3 1 PINIT domain zf-MIZ PF02891.20 CCD23776.1 - 2e-21 75.5 7.2 3.6e-21 74.6 7.2 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 CCD23776.1 - 4.9e-10 38.9 0.1 9.9e-10 38.0 0.1 1.5 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 CCD23776.1 - 8.3e-05 22.3 1.2 0.00019 21.2 1.2 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit WIYLD PF10440.9 CCD23776.1 - 0.00022 21.0 0.9 0.17 11.7 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin-binding WIYLD domain zf-RING_UBOX PF13445.6 CCD23776.1 - 0.023 14.7 2.3 0.054 13.5 2.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CCD23776.1 - 0.18 11.7 4.0 0.37 10.7 4.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCD23776.1 - 2.2 8.5 4.2 4 7.7 4.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING rve PF00665.26 CCD23777.1 - 0.00027 21.1 0.0 0.00043 20.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CCD23777.1 - 0.0021 18.1 0.8 0.0039 17.3 0.8 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Proteasome PF00227.26 CCD23778.1 - 4.9e-49 166.4 0.0 7e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 CCD23778.1 - 9.5e-15 53.7 0.1 9.5e-15 53.7 0.1 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Dna2 PF08696.11 CCD23778.1 - 0.13 12.0 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 DNA replication factor Dna2 SKI PF01202.22 CCD23779.1 - 4.9 7.3 8.4 48 4.0 5.4 3.0 2 1 0 2 2 2 0 Shikimate kinase LSM PF01423.22 CCD23780.1 - 1.5e-14 53.4 0.0 1.9e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CCD23780.1 - 0.00092 18.8 0.1 0.0019 17.8 0.0 1.5 2 0 0 2 2 2 1 Hfq protein Xpo1 PF08389.12 CCD23781.1 - 1e-25 90.5 1.1 1e-25 90.5 1.1 3.8 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 CCD23781.1 - 2.1e-06 27.5 2.1 1.5e-05 24.8 1.3 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.22 CCD23781.1 - 0.073 13.4 0.0 5.5 7.5 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat Choline_transpo PF04515.12 CCD23782.1 - 5.8e-77 259.1 18.0 5.8e-77 259.1 18.0 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter ESSS PF10183.9 CCD23782.1 - 0.012 15.8 0.9 2 8.7 0.1 3.5 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ABC2_membrane PF01061.24 CCD23783.1 - 1.2e-85 286.3 50.4 1.4e-45 155.3 18.6 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CCD23783.1 - 2.6e-38 131.6 0.0 1.6e-18 67.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CCD23783.1 - 3.9e-35 119.6 9.2 1.4e-30 105.0 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 CCD23783.1 - 7.9e-20 71.3 0.0 2.5e-19 69.7 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 CCD23783.1 - 1.3e-07 31.4 0.1 1.8e-05 24.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CCD23783.1 - 8.3e-07 29.5 0.0 9.2e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CCD23783.1 - 1.9e-05 24.6 0.1 0.00052 19.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 CCD23783.1 - 0.00013 22.5 0.0 0.025 15.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CCD23783.1 - 0.00016 21.3 0.6 0.0078 15.9 0.1 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CCD23783.1 - 0.00018 21.4 0.1 0.28 10.9 0.0 3.0 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CCD23783.1 - 0.0019 18.7 1.2 0.013 16.0 0.0 2.8 4 0 0 4 4 3 1 AAA domain cobW PF02492.19 CCD23783.1 - 0.0026 17.4 1.7 0.38 10.3 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 CCD23783.1 - 0.0036 16.8 3.9 0.0099 15.3 0.1 3.1 3 1 0 3 3 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 CCD23783.1 - 0.0036 17.2 0.4 3.2 7.6 0.2 2.6 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 CCD23783.1 - 0.0038 17.5 0.4 0.12 12.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CCD23783.1 - 0.0039 17.3 0.0 0.46 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 CCD23783.1 - 0.0066 15.2 0.2 3.5 6.2 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 CCD23783.1 - 0.017 15.4 3.3 0.42 10.9 0.1 3.2 4 0 0 4 4 3 0 AAA domain dNK PF01712.19 CCD23783.1 - 0.02 14.7 0.0 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase DnaB_C PF03796.15 CCD23783.1 - 0.027 13.8 0.0 0.73 9.1 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_30 PF13604.6 CCD23783.1 - 0.029 14.1 0.3 3.1 7.5 0.3 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CCD23783.1 - 0.15 11.3 0.1 8.1 5.6 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain OCD_Mu_crystall PF02423.15 CCD23783.1 - 0.16 10.9 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family NTPase_1 PF03266.15 CCD23783.1 - 0.18 11.7 0.5 12 5.8 0.1 2.9 3 0 0 3 3 3 0 NTPase ISN1 PF06437.11 CCD23784.1 - 1.2e-182 607.4 0.0 1.4e-182 607.2 0.0 1.1 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Herpes_UL51 PF04540.13 CCD23784.1 - 0.04 13.6 0.1 0.15 11.8 0.0 1.9 3 0 0 3 3 3 0 Herpesvirus UL51 protein Nop PF01798.18 CCD23784.1 - 0.081 12.4 0.2 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin PEHE PF15275.6 CCD23784.1 - 0.1 13.2 0.9 0.26 11.9 0.9 1.7 1 0 0 1 1 1 0 PEHE domain RNA_pol_Rpb2_6 PF00562.28 CCD23786.1 - 1.2e-126 423.0 0.1 1.9e-126 422.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CCD23786.1 - 1.1e-73 247.2 0.1 1.8e-73 246.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CCD23786.1 - 3.6e-51 173.5 0.0 7.1e-51 172.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CCD23786.1 - 2.6e-34 117.5 0.1 5.9e-34 116.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CCD23786.1 - 1.4e-25 89.3 0.3 3.6e-25 88.0 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CCD23786.1 - 2.3e-24 85.3 0.1 6.4e-24 83.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CCD23786.1 - 4.3e-19 68.8 1.1 4.3e-19 68.8 1.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 CCD23786.1 - 0.094 13.5 0.1 0.19 12.5 0.1 1.5 1 0 0 1 1 1 0 MRN-interacting protein Zn_Tnp_IS1595 PF12760.7 CCD23786.1 - 0.14 12.1 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_L13 PF00572.18 CCD23787.1 - 3.9e-47 159.6 0.2 5.1e-47 159.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 MDM31_MDM32 PF08118.11 CCD23788.1 - 1.8e-56 191.9 24.7 4.8e-40 137.7 4.7 4.3 2 2 2 4 4 4 4 Yeast mitochondrial distribution and morphology (MDM) proteins TadF PF16964.5 CCD23788.1 - 0.0042 16.9 1.8 0.0084 15.9 0.0 2.2 2 0 0 2 2 2 1 Putative tight adherence pilin protein F G-patch_2 PF12656.7 CCD23789.1 - 4.4e-18 65.1 0.1 4.4e-18 65.1 0.1 2.6 3 0 0 3 3 3 1 G-patch domain Glyco_transf_22 PF03901.17 CCD23790.1 - 6.2e-71 239.8 34.2 7.5e-71 239.5 34.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PDR_CDR PF06422.12 CCD23790.1 - 0.091 12.7 1.3 0.32 10.9 0.0 2.5 2 0 0 2 2 2 0 CDR ABC transporter DUF368 PF04018.13 CCD23790.1 - 0.94 9.0 15.5 3.3 7.2 0.6 4.2 2 2 2 4 4 4 0 Domain of unknown function (DUF368) CBFD_NFYB_HMF PF00808.23 CCD23791.1 - 9.3e-12 45.1 0.3 1.4e-11 44.5 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2960 PF11173.8 CCD23791.1 - 0.0052 17.2 0.1 0.0081 16.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2960) Lig_C PF18330.1 CCD23791.1 - 0.032 14.2 1.0 0.045 13.7 1.0 1.3 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region ToxN_toxin PF13958.6 CCD23791.1 - 0.035 14.4 0.3 0.046 14.0 0.3 1.1 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system Histone PF00125.24 CCD23791.1 - 0.19 12.1 0.1 0.19 12.1 0.1 2.2 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 PDR_CDR PF06422.12 CCD23792.1 - 0.042 13.7 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 CDR ABC transporter Utp12 PF04003.12 CCD23794.1 - 1.9e-18 66.8 4.4 4.2e-18 65.6 4.4 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family AAA PF00004.29 CCD23795.1 - 8.6e-05 23.0 0.1 0.00081 19.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TPK_catalytic PF04263.16 CCD23796.1 - 3e-31 108.0 2.7 3.9e-30 104.4 2.7 2.1 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CCD23796.1 - 6.2e-12 45.1 0.4 1.7e-11 43.7 0.4 1.7 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF1027 PF06265.11 CCD23796.1 - 0.085 12.9 0.8 0.17 11.9 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) GABP-alpha PF11620.8 CCD23796.1 - 0.09 13.0 0.4 0.23 11.7 0.4 1.7 1 0 0 1 1 1 0 GA-binding protein alpha chain CoA_binding PF02629.19 CCD23797.1 - 1.9e-26 92.6 2.3 2e-26 92.5 0.4 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CCD23797.1 - 1.3e-23 83.5 0.5 2.5e-23 82.6 0.5 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CCD23797.1 - 2.6e-06 27.3 0.0 4.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CCD23797.1 - 0.00021 21.8 0.0 0.00053 20.5 0.0 1.7 2 0 0 2 2 2 1 CoA binding domain IlvN PF07991.12 CCD23797.1 - 0.024 14.2 0.0 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Actin PF00022.19 CCD23798.1 - 2.4e-23 82.4 0.0 2.3e-17 62.7 0.0 3.6 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 CCD23798.1 - 2.9e-11 43.2 1.2 0.0002 20.7 0.2 2.7 2 1 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 CCD23798.1 - 0.0061 15.4 0.0 0.37 9.6 0.0 2.5 2 0 0 2 2 2 1 MreB/Mbl protein LpqV PF17301.2 CCD23798.1 - 0.86 9.9 7.6 0.039 14.2 1.2 2.1 2 0 0 2 2 2 0 Putative lipoprotein LpqV FSA_C PF10479.9 CCD23798.1 - 3.7 5.5 8.4 2.6 6.0 4.2 2.2 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus HSF_DNA-bind PF00447.17 CCD23799.1 - 1.5e-28 99.3 2.5 1.5e-28 99.3 2.5 2.3 2 0 0 2 2 2 1 HSF-type DNA-binding UBA PF00627.31 CCD23800.1 - 5.7e-08 32.5 0.2 1.5e-07 31.1 0.2 1.8 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 CCD23800.1 - 0.0039 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain Metallophos PF00149.28 CCD23801.1 - 2.9e-11 44.2 0.5 2.9e-11 44.2 0.5 2.7 2 2 1 3 3 3 1 Calcineurin-like phosphoesterase Iso_dh PF00180.20 CCD23802.1 - 9e-106 353.9 0.0 1.1e-105 353.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RhoGAP PF00620.27 CCD23803.1 - 2.9e-34 118.1 0.4 8.3e-34 116.6 0.4 1.8 1 1 0 1 1 1 1 RhoGAP domain GTP_EFTU PF00009.27 CCD23804.1 - 2.3e-68 229.6 0.3 2.9e-68 229.2 0.3 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CCD23804.1 - 2.3e-19 69.2 0.0 7.6e-19 67.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 CCD23804.1 - 7e-05 22.9 0.1 0.00014 21.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PX PF00787.24 CCD23805.1 - 5.5e-09 36.0 0.4 1.1e-08 35.0 0.4 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CCD23805.1 - 1.1e-07 31.6 4.1 2.2e-07 30.7 4.1 1.4 1 0 0 1 1 1 1 Vps5 C terminal like RXLR PF16810.5 CCD23805.1 - 0.69 10.4 7.1 0.19 12.1 3.2 2.1 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity HAD_2 PF13419.6 CCD23806.1 - 1.8e-17 64.0 0.6 3.9e-16 59.6 0.1 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCD23806.1 - 4.4e-14 53.3 0.0 3.9e-10 40.4 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCD23806.1 - 2.3e-08 33.9 0.0 4.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 CCD23806.1 - 0.00053 19.8 1.0 0.24 11.1 0.1 3.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 CCD23806.1 - 0.016 14.8 0.0 0.45 10.1 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase HAD PF12710.7 CCD23806.1 - 0.18 12.2 0.0 0.44 10.9 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ribosomal_60s PF00428.19 CCD23807.1 - 1.2e-23 83.5 11.5 1.4e-23 83.3 11.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 CCD23807.1 - 0.18 12.1 0.0 0.26 11.7 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain Mito_carr PF00153.27 CCD23808.1 - 7.7e-60 198.9 0.4 7.2e-20 70.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 CCD23808.1 - 0.0042 17.4 0.0 0.057 13.8 0.0 2.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Aldo_ket_red PF00248.21 CCD23809.1 - 4.7e-63 213.1 0.0 5.3e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CNPase PF05881.12 CCD23809.1 - 0.0096 15.5 0.0 0.035 13.7 0.0 1.8 2 0 0 2 2 2 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) SPA PF08616.10 CCD23810.1 - 4.3e-27 94.3 0.7 1.2e-26 92.9 0.7 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 CCD23810.1 - 2.3e-26 92.9 2.0 2.3e-26 92.8 0.1 2.1 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking AIRC PF00731.20 CCD23811.1 - 2.4e-62 208.9 0.6 9.5e-62 207.0 0.4 2.0 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 CCD23811.1 - 4.2e-59 198.9 0.0 6.4e-59 198.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 CCD23811.1 - 5.8e-16 57.9 0.0 1.1e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 CCD23811.1 - 3.1e-05 23.6 0.0 5.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.19 CCD23811.1 - 0.0012 18.3 0.0 0.0032 16.8 0.0 1.8 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.13 CCD23811.1 - 0.023 14.2 0.0 0.16 11.5 0.0 2.2 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus PrpR_N PF06506.11 CCD23811.1 - 0.044 13.4 0.4 9.1 5.8 0.1 2.6 2 0 0 2 2 2 0 Propionate catabolism activator TrkA_N PF02254.18 CCD23811.1 - 0.044 14.0 0.1 0.091 13.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain ATP-grasp_3 PF02655.14 CCD23811.1 - 0.061 13.4 0.0 0.22 11.5 0.0 2.1 2 1 0 2 2 2 0 ATP-grasp domain AlaDh_PNT_C PF01262.21 CCD23811.1 - 0.1 11.8 0.1 0.3 10.4 0.1 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RhoGAP PF00620.27 CCD23812.1 - 3.3e-41 140.6 0.7 8.7e-41 139.3 0.7 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 CCD23812.1 - 9.8e-11 41.7 32.0 8e-06 26.0 11.9 2.8 3 0 0 3 3 3 2 LIM domain DHR10 PF18595.1 CCD23812.1 - 0.19 11.8 9.6 0.041 13.9 3.9 2.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF4065 PF13274.6 CCD23812.1 - 1.2 10.1 0.0 1.2 10.1 0.0 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF4065) Lipase_GDSL_2 PF13472.6 CCD23813.1 - 1.1e-20 74.7 0.0 1.5e-20 74.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CCD23813.1 - 4e-15 56.3 0.0 1.3e-14 54.6 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BCS1_N PF08740.11 CCD23814.1 - 1.7e-45 155.3 0.0 2.7e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CCD23814.1 - 2.3e-21 76.6 0.0 5.8e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CCD23814.1 - 0.00026 20.8 0.0 0.0025 17.6 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CCD23814.1 - 0.00053 19.2 0.0 0.00088 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 CCD23814.1 - 0.00081 19.8 0.0 0.009 16.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 CCD23814.1 - 0.0014 18.2 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 CCD23814.1 - 0.0017 18.3 0.0 0.35 10.8 0.0 3.0 2 1 1 3 3 3 1 NACHT domain AAA_5 PF07728.14 CCD23814.1 - 0.0046 17.0 0.0 0.013 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CCD23814.1 - 0.0047 17.5 0.0 0.014 15.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CCD23814.1 - 0.0058 16.8 0.0 0.0093 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CCD23814.1 - 0.0082 15.9 0.0 0.03 14.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CCD23814.1 - 0.02 15.4 0.0 0.042 14.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 CCD23814.1 - 0.024 15.0 0.0 0.096 13.1 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA_29 PF13555.6 CCD23814.1 - 0.031 14.0 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 CCD23814.1 - 0.048 13.5 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_11 PF13086.6 CCD23814.1 - 0.051 13.4 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CCD23814.1 - 0.062 13.2 0.0 0.9 9.4 0.0 2.1 1 1 1 2 2 2 0 Rad17 P-loop domain ATPase PF06745.13 CCD23814.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 CCD23814.1 - 0.074 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CCD23814.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Gram_pos_anchor PF00746.21 CCD23814.1 - 0.14 12.1 0.5 0.3 11.0 0.5 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif TsaE PF02367.17 CCD23814.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MAPEG PF01124.18 CCD23814.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 MAPEG family IMUP PF15761.5 CCD23814.1 - 1.8 9.3 5.1 3.3 8.4 5.1 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein COQ7 PF03232.13 CCD23815.1 - 6.5e-73 244.1 0.1 7.8e-73 243.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 DUF1978 PF09321.10 CCD23815.1 - 0.0077 15.6 0.2 0.026 13.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1978) Rubrerythrin PF02915.17 CCD23815.1 - 0.0089 16.4 0.1 0.032 14.6 0.0 2.0 1 1 0 2 2 2 1 Rubrerythrin GA PF01468.17 CCD23815.1 - 0.11 12.7 0.1 0.34 11.2 0.1 1.8 1 0 0 1 1 1 0 GA module UCH PF00443.29 CCD23816.1 - 2.8e-55 187.6 0.4 6.9e-55 186.3 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 CCD23816.1 - 2.9e-46 155.2 9.8 8.3e-19 67.3 0.5 5.2 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.6 CCD23816.1 - 0.00052 19.7 5.5 0.036 13.7 0.2 2.8 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Retrotrans_gag PF03732.17 CCD23817.1 - 7.5e-05 22.9 0.1 0.00014 22.1 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 CCD23817.1 - 0.0087 16.1 5.5 0.019 15.0 5.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CCD23817.1 - 0.1 12.6 3.1 0.21 11.6 3.1 1.5 1 0 0 1 1 1 0 Zinc knuckle P53_TAD PF08563.11 CCD23817.1 - 0.13 11.7 1.3 0.24 10.9 1.3 1.4 1 0 0 1 1 1 0 P53 transactivation motif RVT_1 PF00078.27 CCD23818.1 - 5e-31 107.9 0.1 9e-31 107.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CCD23818.1 - 2.1e-28 98.3 0.0 5.9e-28 96.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCD23818.1 - 4.5e-28 97.6 0.0 9.9e-28 96.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CCD23818.1 - 1.6e-17 63.3 2.4 1.6e-17 63.3 2.4 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Peptidase_A2B PF12384.8 CCD23818.1 - 2.2e-17 63.2 0.1 4.9e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Ty3 transposon peptidase rve PF00665.26 CCD23818.1 - 1.2e-14 54.5 0.1 3.6e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 CCD23818.1 - 3.8e-05 24.2 0.0 7.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 CCD23818.1 - 0.00021 21.4 1.1 0.0013 18.9 0.1 2.8 2 0 0 2 2 2 1 H2C2 zinc finger RVP_2 PF08284.11 CCD23818.1 - 0.015 15.1 0.1 0.031 14.0 0.1 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CCD23818.1 - 0.018 15.6 0.0 0.037 14.6 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Profilin PF00235.19 CCD23819.1 - 7.5e-48 162.0 0.1 8.3e-48 161.9 0.1 1.0 1 0 0 1 1 1 1 Profilin NTNH_C PF08470.10 CCD23819.1 - 0.084 12.8 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal Leo1 PF04004.13 CCD23820.1 - 1.7e-48 164.6 0.1 1.7e-48 164.6 0.1 3.1 3 1 0 3 3 3 1 Leo1-like protein MDH PF02315.16 CCD23820.1 - 5.3 7.2 5.8 17 5.6 1.1 2.5 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit BUD22 PF09073.10 CCD23820.1 - 8.3 5.6 54.1 0.44 9.8 20.7 2.4 2 0 0 2 2 2 0 BUD22 Aldo_ket_red PF00248.21 CCD23821.1 - 2e-50 171.6 0.0 1.9e-48 165.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family TLD PF07534.16 CCD23822.1 - 4e-26 91.9 0.7 4.5e-25 88.5 0.7 2.4 1 1 0 1 1 1 1 TLD PALB2_WD40 PF16756.5 CCD23822.1 - 0.045 12.7 0.1 0.076 11.9 0.1 1.2 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain RNA_pol_Rpb1_5 PF04998.17 CCD23823.1 - 7.1e-83 278.1 0.1 1e-82 277.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 CCD23823.1 - 3.2e-81 273.1 0.0 8.6e-81 271.7 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CCD23823.1 - 2.4e-76 255.6 0.0 5e-76 254.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CCD23823.1 - 2.2e-39 134.9 0.0 5.4e-39 133.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CCD23823.1 - 6.9e-31 106.4 0.1 1.8e-30 105.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Peptidase_M18 PF02127.15 CCD23824.1 - 2e-178 593.7 0.1 2.3e-178 593.4 0.1 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CCD23824.1 - 5.1e-09 35.6 0.0 5.3e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase EMP24_GP25L PF01105.24 CCD23825.1 - 4.8e-47 160.3 3.9 5.5e-47 160.1 3.9 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 CCD23825.1 - 0.0038 17.4 0.1 0.0055 16.9 0.1 1.3 1 0 0 1 1 1 1 SdrD B-like domain TACC_C PF05010.14 CCD23825.1 - 0.0069 16.2 0.9 0.011 15.6 0.9 1.2 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF148 PF02520.17 CCD23825.1 - 0.03 14.4 0.8 0.056 13.6 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF4140 PF13600.6 CCD23825.1 - 0.059 13.8 0.1 0.1 13.0 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) CBP_BcsF PF11120.8 CCD23825.1 - 0.25 11.5 0.9 0.46 10.6 0.9 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF Tail_VII PF17091.5 CCD23825.1 - 0.77 9.7 2.9 1.4 8.8 2.9 1.4 1 0 0 1 1 1 0 Inovirus G7P protein Septin PF00735.18 CCD23827.1 - 4e-115 383.9 0.0 5.7e-115 383.4 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CCD23827.1 - 4.5e-07 29.9 0.0 9.2e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CCD23827.1 - 0.00027 21.2 0.0 0.00057 20.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF3987 PF13148.6 CCD23827.1 - 0.00042 19.4 0.2 0.51 9.3 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) RsgA_GTPase PF03193.16 CCD23827.1 - 0.00085 19.3 5.5 0.001 19.0 0.3 3.1 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 CCD23827.1 - 0.00095 18.8 1.8 0.048 13.2 0.1 2.8 2 2 0 3 3 3 1 Elongation factor Tu GTP binding domain Roc PF08477.13 CCD23827.1 - 0.0023 18.1 0.5 0.0056 16.9 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CCD23827.1 - 0.0039 17.3 3.5 4.6 7.3 0.0 3.2 2 1 1 3 3 3 1 Dynamin family AAA_16 PF13191.6 CCD23827.1 - 0.0092 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 CCD23827.1 - 0.013 15.9 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase G-alpha PF00503.20 CCD23827.1 - 0.013 14.6 0.4 0.025 13.7 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit IIGP PF05049.13 CCD23827.1 - 0.017 14.2 0.3 0.13 11.3 0.1 2.2 1 1 1 2 2 2 0 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.12 CCD23827.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AIG1 PF04548.16 CCD23827.1 - 0.033 13.5 0.0 0.076 12.3 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_24 PF13479.6 CCD23827.1 - 0.037 13.8 0.5 0.11 12.2 0.5 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CCD23827.1 - 0.048 13.6 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 CCD23827.1 - 0.052 14.1 0.1 0.17 12.4 0.0 1.9 2 0 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.18 CCD23827.1 - 0.057 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 CCD23827.1 - 0.083 12.4 0.1 0.24 10.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 CCD23827.1 - 0.088 12.5 1.7 0.2 11.4 0.3 2.3 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.26 CCD23827.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Pyr_redox_2 PF07992.14 CCD23828.1 - 2.8e-50 171.2 0.1 3.3e-50 171.0 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCD23828.1 - 3.4e-19 69.2 0.2 1.6e-16 60.6 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCD23828.1 - 1.3e-15 57.5 0.2 5.1e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CCD23828.1 - 1.3e-06 27.8 0.2 0.54 9.3 0.1 4.1 4 0 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_7 PF13241.6 CCD23828.1 - 0.00021 21.7 0.0 0.039 14.4 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 CCD23828.1 - 0.00084 18.7 0.0 0.0058 15.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 CCD23828.1 - 0.0013 18.9 0.0 0.23 11.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 CCD23828.1 - 0.0065 15.6 0.0 0.98 8.5 0.0 3.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 CCD23828.1 - 0.0066 15.6 3.5 0.88 8.6 0.2 3.1 2 2 2 4 4 4 2 FAD binding domain FAD_binding_3 PF01494.19 CCD23828.1 - 0.0096 15.2 0.2 3 7.0 0.1 2.7 2 1 1 3 3 3 2 FAD binding domain Shikimate_DH PF01488.20 CCD23828.1 - 0.012 15.6 0.0 5.4 7.1 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 CCD23828.1 - 0.03 13.7 0.5 0.45 9.8 0.1 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.24 CCD23828.1 - 0.039 13.5 0.4 1.3 8.5 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 CCD23828.1 - 0.061 12.0 0.4 2.6 6.6 0.2 2.8 2 1 1 3 3 3 0 HI0933-like protein PX PF00787.24 CCD23829.1 - 6e-15 55.2 0.0 7.6e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 PX domain TRL PF13146.6 CCD23829.1 - 0.15 12.3 0.4 0.26 11.6 0.4 1.4 1 0 0 1 1 1 0 TRL-like protein family SBE2 PF17076.5 CCD23830.1 - 2.6e-301 1001.8 34.6 3e-301 1001.6 34.6 1.0 1 0 0 1 1 1 1 SBE2, cell-wall formation Pkinase PF00069.25 CCD23831.1 - 1.7e-72 244.0 0.0 2.7e-72 243.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23831.1 - 1.6e-52 178.3 0.0 2.5e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCD23831.1 - 2.4e-07 29.9 0.1 2e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CCD23831.1 - 4.3e-05 23.0 0.0 0.0011 18.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF4847 PF16139.5 CCD23831.1 - 0.05 13.5 4.6 0.078 12.9 3.2 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4847) FTA2 PF13095.6 CCD23831.1 - 0.12 12.0 0.4 2.6 7.6 0.0 2.5 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PGP_phosphatase PF09419.10 CCD23833.1 - 3.7e-70 234.9 0.0 4.4e-70 234.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 CCD23833.1 - 0.0016 18.4 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Sec23_trunk PF04811.15 CCD23834.1 - 5.7e-54 183.3 0.0 9.6e-54 182.5 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CCD23834.1 - 2.2e-18 66.0 0.1 4.9e-18 64.8 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CCD23834.1 - 2e-11 44.5 0.2 7.9e-11 42.5 0.0 2.2 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CCD23834.1 - 6.1e-11 42.2 3.9 1.3e-10 41.1 2.8 2.1 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CCD23834.1 - 0.0013 18.6 0.0 0.0037 17.1 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.6 CCD23834.1 - 0.16 12.7 0.0 2.6 8.7 0.0 2.5 2 0 0 2 2 2 0 von Willebrand factor type A domain DUF2318 PF10080.9 CCD23834.1 - 0.18 12.0 0.8 0.53 10.4 0.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Sugar_tr PF00083.24 CCD23835.1 - 5.2e-165 549.7 35.6 6.5e-165 549.4 35.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD23835.1 - 1.5e-33 116.2 41.1 8.8e-31 107.1 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCD23836.1 - 1.8e-171 571.0 33.2 2e-171 570.8 33.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD23836.1 - 4.2e-25 88.4 22.3 4.2e-25 88.4 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily tRNA-synt_1d PF00750.19 CCD23837.1 - 3.4e-123 411.0 5.6 4.3e-123 410.7 5.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CCD23837.1 - 8.8e-30 103.3 0.5 2.1e-28 98.9 0.1 2.5 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CCD23837.1 - 1.1e-07 32.4 0.0 7.9e-07 29.6 0.0 2.5 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain BRCA2 PF00634.18 CCD23837.1 - 0.096 12.4 0.8 0.24 11.1 0.8 1.7 1 0 0 1 1 1 0 BRCA2 repeat ING PF12998.7 CCD23838.1 - 1.6e-19 70.4 4.6 1.6e-19 70.4 4.6 1.7 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CCD23838.1 - 2.4e-06 27.3 8.4 4.7e-06 26.4 8.4 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CCD23838.1 - 0.0059 16.8 1.1 0.014 15.6 1.1 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain STAT_alpha PF01017.20 CCD23838.1 - 0.05 13.5 3.9 0.12 12.3 3.9 1.6 1 0 0 1 1 1 0 STAT protein, all-alpha domain Attractin PF08037.11 CCD23838.1 - 0.058 13.4 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Attractin family DUF4749 PF15936.5 CCD23838.1 - 1.1 10.5 5.5 0.6 11.2 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4749) Gar1 PF04410.14 CCD23839.1 - 8.7e-41 139.3 0.0 1e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Xpo1 PF08389.12 CCD23840.1 - 0.00096 19.2 2.4 0.051 13.6 2.4 3.4 1 1 0 1 1 1 1 Exportin 1-like protein NES_C_h PF18208.1 CCD23840.1 - 0.089 13.1 1.4 0.47 10.7 0.3 2.7 2 0 0 2 2 2 0 Nicking enzyme C-terminal middle helical domain Brix PF04427.18 CCD23841.1 - 2.2e-26 93.2 0.8 2.2e-26 93.2 0.8 1.5 2 0 0 2 2 2 1 Brix domain Pex19 PF04614.12 CCD23841.1 - 0.021 14.6 5.5 0.038 13.8 5.5 1.4 1 0 0 1 1 1 0 Pex19 protein family SBDS PF01172.18 CCD23842.1 - 2e-17 63.0 0.2 3.1e-17 62.4 0.2 1.2 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RRM_1 PF00076.22 CCD23843.1 - 2.3e-43 145.9 0.0 3.5e-15 55.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD23843.1 - 7.4e-05 22.8 0.1 0.035 14.2 0.0 3.5 3 0 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 CCD23843.1 - 0.00013 21.7 0.0 0.57 10.1 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CCD23843.1 - 0.022 14.8 0.0 0.27 11.3 0.0 2.6 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CCD23843.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif STE PF02200.16 CCD23844.1 - 2.9e-33 114.6 1.2 5.4e-33 113.7 1.2 1.4 1 0 0 1 1 1 1 STE like transcription factor SDH_beta PF03315.15 CCD23844.1 - 0.0099 16.3 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 1 Serine dehydratase beta chain Cwf_Cwc_15 PF04889.12 CCD23844.1 - 0.011 15.5 2.2 0.011 15.5 2.2 3.4 3 1 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein SAM35 PF10806.8 CCD23845.1 - 3.1e-40 137.3 6.5 5.4e-40 136.6 1.9 2.5 3 0 0 3 3 3 1 SAM35, subunit of SAM coomplex G_glu_transpept PF01019.21 CCD23845.1 - 0.056 12.2 0.5 0.081 11.7 0.5 1.2 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase DUF4174 PF13778.6 CCD23845.1 - 0.069 13.6 1.8 0.18 12.2 1.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) Popeye PF04831.13 CCD23845.1 - 0.088 13.0 0.3 0.16 12.1 0.1 1.6 2 0 0 2 2 2 0 Popeye protein conserved region Pkinase PF00069.25 CCD23846.1 - 1.1e-42 146.3 0.1 3.2e-38 131.6 0.1 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23846.1 - 7.6e-21 74.5 0.0 4.9e-20 71.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD23846.1 - 5.4e-05 22.6 1.2 0.00025 20.5 0.0 2.3 2 1 1 3 3 3 1 Kinase-like Sas10_Utp3 PF04000.15 CCD23847.1 - 0.0013 19.3 3.8 0.0013 19.3 3.8 2.7 2 1 1 3 3 3 1 Sas10/Utp3/C1D family DUF2981 PF11200.8 CCD23847.1 - 0.39 10.4 8.0 0.48 10.1 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) POPLD PF08170.12 CCD23847.1 - 0.54 10.6 3.7 1.5 9.3 1.7 2.2 2 0 0 2 2 2 0 POPLD (NUC188) domain C2-set PF05790.15 CCD23847.1 - 2.3 8.5 8.5 0.78 10.0 3.8 2.5 1 1 1 2 2 2 0 Immunoglobulin C2-set domain VASt PF16016.5 CCD23848.1 - 8.5e-67 224.3 14.6 9.5e-36 123.5 0.3 3.5 4 0 0 4 4 4 2 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CCD23848.1 - 1.6e-24 86.0 1.5 1.6e-24 86.0 1.5 2.3 3 0 0 3 3 3 1 GRAM domain Ribonuc_2-5A PF06479.12 CCD23849.1 - 3.8e-43 146.7 2.4 4.8e-43 146.4 0.7 2.1 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.25 CCD23849.1 - 1.4e-42 145.9 0.0 4.1e-31 108.3 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23849.1 - 8.6e-21 74.4 0.0 3.2e-18 65.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ PF01011.21 CCD23849.1 - 3.1e-05 23.7 0.3 0.28 11.2 0.0 3.9 4 0 0 4 4 4 2 PQQ enzyme repeat Pkinase_fungal PF17667.1 CCD23849.1 - 0.00036 19.4 2.7 0.00036 19.4 2.7 2.1 2 2 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CCD23849.1 - 0.002 17.5 0.1 0.0041 16.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.6 CCD23849.1 - 0.012 15.2 0.0 0.074 12.6 0.0 2.1 1 1 0 1 1 1 0 PQQ-like domain ABA_GPCR PF12430.8 CCD23850.1 - 4.7e-63 212.2 6.1 4.7e-63 212.2 6.1 2.8 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CCD23850.1 - 1.5e-16 60.2 0.1 3.5e-16 59.0 0.1 1.7 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal MIF4G PF02854.19 CCD23851.1 - 3.2e-43 147.8 32.7 1.4e-22 80.4 2.6 3.6 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 CCD23851.1 - 4.6e-25 88.9 12.3 4.6e-25 88.9 12.3 3.0 2 1 1 3 3 3 1 Up-frameshift suppressor 2 Nop14 PF04147.12 CCD23851.1 - 0.13 10.5 33.0 0.32 9.1 33.0 1.7 1 0 0 1 1 1 0 Nop14-like family SpoIIE PF07228.12 CCD23852.1 - 3.8e-30 105.2 0.0 4.9e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CCD23852.1 - 7.3e-09 35.6 0.5 9.8e-05 22.1 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Reovirus_M2 PF05993.12 CCD23852.1 - 0.0015 16.7 0.1 0.0019 16.4 0.1 1.2 1 0 0 1 1 1 1 Reovirus major virion structural protein Mu-1/Mu-1C (M2) PPC PF04151.15 CCD23852.1 - 0.019 16.0 1.2 0.019 16.0 1.2 2.4 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Trp_repressor PF01371.19 CCD23853.1 - 0.056 13.6 0.6 0.52 10.5 0.1 2.6 2 0 0 2 2 2 0 Trp repressor protein Nmad5 PF18757.1 CCD23853.1 - 0.78 9.9 7.0 0.41 10.8 4.0 2.0 2 0 0 2 2 2 0 Nucleotide modification associated domain 5 Abhydrolase_6 PF12697.7 CCD23854.1 - 2e-20 74.4 0.0 2.6e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CCD23854.1 - 6.6e-14 52.2 0.0 9.8e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCD23854.1 - 1.8e-07 30.7 0.0 3.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 CCD23854.1 - 0.0019 18.1 0.0 0.0044 16.9 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 CCD23854.1 - 0.0066 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 CCD23854.1 - 0.034 13.6 0.1 0.071 12.6 0.1 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 CCD23854.1 - 0.05 13.1 0.1 0.084 12.4 0.1 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF2974 PF11187.8 CCD23854.1 - 0.053 13.1 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) VirJ PF06057.11 CCD23854.1 - 0.094 12.6 0.0 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) CN_hydrolase PF00795.22 CCD23855.1 - 2.5e-46 158.1 0.0 3.3e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 CCD23855.1 - 1e-21 77.2 0.0 3.2e-21 75.6 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Oxysterol_BP PF01237.18 CCD23856.1 - 2.1e-102 342.7 5.9 2e-101 339.5 5.9 2.3 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 CCD23856.1 - 2.2e-33 114.4 0.6 2.2e-33 114.4 0.6 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CCD23856.1 - 3.2e-06 27.6 2.0 1.1e-05 25.8 0.7 2.8 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 CCD23856.1 - 0.001 19.2 0.3 0.0045 17.1 0.3 2.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CCD23856.1 - 1.8 9.1 13.3 1.4 9.4 4.9 4.1 3 1 0 3 3 3 0 Pleckstrin homology domain SQHop_cyclase_C PF13243.6 CCD23857.1 - 4.8e-43 147.5 0.2 2.6e-42 145.1 0.1 1.9 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CCD23857.1 - 3.1e-37 128.3 0.0 8.5e-33 113.7 0.0 3.6 2 1 2 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 CCD23857.1 - 8.4e-26 89.4 0.2 1.9e-08 33.9 0.0 4.2 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 CCD23857.1 - 0.004 16.2 0.4 0.018 14.1 0.2 2.0 2 0 0 2 2 2 1 A-macroglobulin TED domain Cyclin_N PF00134.23 CCD23858.1 - 3.2e-06 26.9 2.0 3.2e-06 26.9 0.6 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCD23858.1 - 3.9e-06 27.3 2.2 5.4e-06 26.9 2.2 1.2 1 0 0 1 1 1 1 Cyclin Met_10 PF02475.16 CCD23859.1 - 2.3e-75 252.7 0.2 4.1e-75 251.9 0.2 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 CCD23859.1 - 0.0056 16.4 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase DUF4221 PF13970.6 CCD23859.1 - 0.0067 16.0 0.2 0.011 15.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4221) TRM PF02005.16 CCD23859.1 - 0.0085 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase DUF1140 PF06600.11 CCD23859.1 - 0.095 13.1 0.1 0.24 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) ECR1_N PF14382.6 CCD23860.1 - 7e-16 57.7 0.1 1.3e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 CCD23860.1 - 1.3e-09 38.2 0.2 2.7e-09 37.2 0.2 1.5 1 0 0 1 1 1 1 KH domain DS PF01916.17 CCD23861.1 - 1.1e-133 444.9 0.0 1.3e-133 444.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase MaoC_dehydratas PF01575.19 CCD23862.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 MaoC like domain GYF PF02213.16 CCD23862.1 - 0.084 12.6 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 GYF domain BSD PF03909.17 CCD23863.1 - 5e-20 71.2 7.6 2.8e-11 43.2 0.7 3.4 4 0 0 4 4 4 2 BSD domain PH_TFIIH PF08567.11 CCD23863.1 - 1.3e-19 70.3 0.2 2.9e-19 69.2 0.2 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain UCH PF00443.29 CCD23863.1 - 0.039 13.5 0.2 0.039 13.5 0.2 2.3 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase RNase_PH PF01138.21 CCD23864.1 - 2.7e-19 70.0 0.0 4.6e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CCD23864.1 - 4.3e-17 61.9 0.1 8.4e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RNase_P_p30 PF01876.16 CCD23865.1 - 3e-73 245.9 0.2 3.6e-73 245.6 0.2 1.1 1 0 0 1 1 1 1 RNase P subunit p30 ApbA PF02558.16 CCD23867.1 - 3.3e-30 104.7 0.0 5.4e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 CCD23867.1 - 5.8e-29 100.8 0.2 9.4e-29 100.2 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Med31 PF05669.12 CCD23867.1 - 0.097 12.7 0.1 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 SOH1 Bromo_TP_like PF17027.5 CCD23867.1 - 0.41 10.8 3.1 7.1 6.8 0.2 2.6 2 0 0 2 2 2 0 Histone-fold protein HSP70 PF00012.20 CCD23868.1 - 4.7e-74 249.7 3.3 1.1e-73 248.4 0.5 2.1 1 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CCD23868.1 - 2.8e-09 36.3 0.0 4.2e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein HAD_2 PF13419.6 CCD23869.1 - 3.4e-18 66.4 0.0 5.2e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCD23869.1 - 3e-08 34.2 0.1 5.5e-07 30.1 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCD23869.1 - 0.01 15.9 0.1 0.02 14.9 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 CCD23870.1 - 2.8e-19 69.9 0.0 3.6e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCD23870.1 - 6.1e-09 36.5 0.0 4.3e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CCD23870.1 - 0.0028 18.1 0.0 0.0039 17.6 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCD23870.1 - 0.024 14.7 0.1 0.044 13.8 0.1 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like FAD_binding_1 PF00667.20 CCD23871.1 - 2.7e-65 220.1 0.0 5e-65 219.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CCD23871.1 - 1.5e-28 99.8 0.6 2.7e-28 99.0 0.6 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CCD23871.1 - 1.5e-21 77.1 0.0 3.8e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Spore_IV_A PF09547.10 CCD23871.1 - 0.011 14.7 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Med20 PF08612.11 CCD23872.1 - 9.3e-33 113.5 0.4 1.1e-32 113.3 0.4 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex ComP_DUS PF16732.5 CCD23872.1 - 0.33 11.9 2.0 6 7.8 0.2 2.2 2 0 0 2 2 2 0 Type IV minor pilin ComP, DNA uptake sequence receptor V-ATPase_G PF03179.15 CCD23873.1 - 9.1e-31 106.5 10.6 1.1e-30 106.3 10.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 CCD23873.1 - 0.00042 20.7 8.4 0.00059 20.2 8.4 1.2 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 CCD23873.1 - 0.0023 18.0 10.7 0.0082 16.2 10.8 1.7 1 1 0 1 1 1 1 ATP synthase B/B' CF(0) S_layer_C PF05124.12 CCD23873.1 - 0.0028 17.7 4.4 0.0033 17.4 4.4 1.0 1 0 0 1 1 1 1 S-layer like family, C-terminal region RE_AlwI PF09491.10 CCD23873.1 - 0.1 11.4 6.4 0.14 10.9 6.4 1.4 1 1 0 1 1 1 0 AlwI restriction endonuclease DUF3552 PF12072.8 CCD23873.1 - 0.18 11.2 14.9 0.078 12.4 6.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Aldedh PF00171.22 CCD23874.1 - 3.5e-113 378.5 0.0 4.6e-113 378.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRF PF01765.19 CCD23875.1 - 1.3e-32 113.0 5.4 2e-32 112.4 5.4 1.3 1 0 0 1 1 1 1 Ribosome recycling factor FA_hydroxylase PF04116.13 CCD23876.1 - 2e-22 79.9 6.4 2e-22 79.9 6.4 2.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Sec23_trunk PF04811.15 CCD23877.1 - 4.4e-11 42.8 4.1 1.2e-10 41.4 4.1 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 CCD23877.1 - 3.1e-06 27.1 2.0 1.3e-05 25.2 2.0 2.2 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Tmemb_55A PF09788.9 CCD23877.1 - 0.0063 15.6 0.1 0.011 14.9 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein 55A zinc_ribbon_10 PF10058.9 CCD23877.1 - 0.11 12.2 0.5 0.28 11.0 0.5 1.7 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Brr6_like_C_C PF10104.9 CCD23878.1 - 7.4e-40 135.8 3.4 1.3e-39 135.0 3.4 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain RRN3 PF05327.11 CCD23878.1 - 1.6 7.2 5.7 2.8 6.4 5.7 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4834 PF16118.5 CCD23878.1 - 3.7 8.6 0.0 3.7 8.6 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Aldedh PF00171.22 CCD23879.1 - 1.5e-98 330.3 0.0 1.8e-98 330.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pih1_fungal_CS PF18482.1 CCD23880.1 - 4.1e-31 107.3 5.0 4.1e-31 107.3 5.0 2.1 3 0 0 3 3 3 1 Fungal Pih1 CS domain PIH1 PF08190.12 CCD23880.1 - 8.4e-20 70.9 2.6 3.9e-19 68.7 0.4 2.4 1 1 0 2 2 2 1 PIH1 N-terminal domain AA_kinase PF00696.28 CCD23881.1 - 9.8e-28 97.4 1.6 7.9e-25 87.8 0.2 2.3 2 0 0 2 2 2 2 Amino acid kinase family PUA PF01472.20 CCD23881.1 - 1.7e-12 47.1 0.0 3.6e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 PUA domain PGM_PMM_I PF02878.16 CCD23882.1 - 1.6e-19 70.0 0.2 2.7e-19 69.2 0.2 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CCD23882.1 - 1.5e-12 48.0 0.0 2.5e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CCD23882.1 - 5e-11 42.8 0.0 1.1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Nup192 PF11894.8 CCD23883.1 - 0 1530.3 84.4 0 1529.4 84.4 1.4 1 1 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nsp1_C PF05064.13 CCD23884.1 - 1.9e-41 140.5 6.5 1.9e-41 140.5 6.5 2.0 1 1 1 2 2 2 1 Nsp1-like C-terminal region DUF16 PF01519.16 CCD23884.1 - 0.21 12.1 10.8 0.043 14.3 2.0 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 RabGAP-TBC PF00566.18 CCD23885.1 - 2.1e-12 47.1 13.3 7.9e-12 45.3 13.3 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain LRR_4 PF12799.7 CCD23886.1 - 3.3 8.3 14.3 0.45 11.0 1.9 4.6 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Dynamin_M PF01031.20 CCD23887.1 - 6.4e-105 350.4 0.1 1.8e-104 349.0 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CCD23887.1 - 7.4e-55 185.6 0.1 7.4e-55 185.6 0.1 3.1 4 0 0 4 4 4 1 Dynamin family GED PF02212.18 CCD23887.1 - 1.3e-29 102.2 4.8 3.6e-29 100.8 4.8 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CCD23887.1 - 4.8e-05 23.4 0.4 0.00058 19.9 0.4 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Fasciclin PF02469.22 CCD23888.1 - 2.5e-17 63.3 8.7 2.4e-06 27.8 0.3 6.3 5 2 0 5 5 5 5 Fasciclin domain DUF3969 PF13108.6 CCD23888.1 - 0.07 13.1 0.2 0.22 11.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) PX PF00787.24 CCD23889.1 - 1.1e-24 86.6 0.3 1.1e-24 86.6 0.3 2.3 3 0 0 3 3 2 1 PX domain Nup88 PF10168.9 CCD23889.1 - 5e-05 21.3 5.2 5e-05 21.3 5.2 1.7 2 0 0 2 2 2 1 Nuclear pore component Vps5 PF09325.10 CCD23889.1 - 7.5e-05 22.4 19.0 0.027 14.0 19.0 2.6 1 1 0 1 1 1 1 Vps5 C terminal like SbsC_C PF18058.1 CCD23889.1 - 0.017 15.3 6.1 0.088 13.0 1.3 2.7 2 0 0 2 2 2 0 SbsC C-terminal domain DUF1804 PF08822.11 CCD23889.1 - 0.063 13.3 1.3 0.12 12.4 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) FlaC_arch PF05377.11 CCD23889.1 - 0.15 12.4 8.5 1.4 9.4 0.5 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 CCD23889.1 - 0.2 12.2 8.5 2.1 8.8 4.2 3.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 CCD23889.1 - 1 9.4 7.7 0.67 10.0 1.6 2.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 CCD23889.1 - 1.2 9.5 5.3 0.73 10.1 1.7 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) T3SSipB PF16535.5 CCD23889.1 - 1.2 9.6 6.6 0.38 11.2 0.9 2.6 1 1 0 2 2 2 0 Type III cell invasion protein SipB Gp-FAR-1 PF05823.12 CCD23889.1 - 1.8 8.9 10.7 0.19 12.1 4.5 2.4 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Rootletin PF15035.6 CCD23889.1 - 2.2 8.3 13.5 0.13 12.3 3.8 2.4 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 CCD23889.1 - 2.2 8.8 16.4 0.27 11.7 3.0 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4618 PF15397.6 CCD23889.1 - 3.4 7.0 21.3 7.2 5.9 19.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) TMPIT PF07851.13 CCD23889.1 - 3.9 6.6 13.1 0.06 12.6 2.7 2.6 1 1 2 3 3 3 0 TMPIT-like protein CENP-F_leu_zip PF10473.9 CCD23889.1 - 4.1 7.4 18.3 0.25 11.4 8.5 2.7 3 0 0 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.6 CCD23889.1 - 5.3 7.4 6.9 13 6.2 0.3 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4164) YabA PF06156.13 CCD23889.1 - 6.1 7.6 11.6 0.25 12.0 1.5 3.2 1 1 1 2 2 2 0 Initiation control protein YabA CRR7 PF12095.8 CCD23889.1 - 9.8 6.7 7.8 0.44 11.0 0.4 2.7 3 1 1 4 4 3 0 Protein CHLORORESPIRATORY REDUCTION 7 dCMP_cyt_deam_1 PF00383.23 CCD23890.1 - 3.4e-21 75.0 0.2 5.4e-21 74.4 0.2 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCD23890.1 - 1.3e-14 54.1 0.0 2.3e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 CCD23890.1 - 0.00075 19.4 0.1 0.0012 18.7 0.1 1.3 1 0 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 CCD23890.1 - 0.0043 17.2 0.0 0.0088 16.2 0.0 1.5 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 CCD23890.1 - 0.012 15.7 0.3 0.044 13.9 0.0 2.0 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 Inv-AAD PF18785.1 CCD23890.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase Bd3614-deam PF14439.6 CCD23890.1 - 0.053 13.6 0.9 0.25 11.4 0.9 2.0 1 1 0 1 1 1 0 Bd3614-like deaminase APOBEC2 PF18772.1 CCD23890.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 APOBEC2 HSP70 PF00012.20 CCD23891.1 - 5.1e-262 870.4 12.3 5.9e-262 870.2 12.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCD23891.1 - 3e-19 69.0 1.7 7.3e-18 64.5 0.3 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CCD23891.1 - 0.0018 18.7 5.7 0.96 9.9 0.3 3.8 3 2 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.20 CCD23891.1 - 0.0038 16.8 0.3 0.1 12.1 0.3 2.3 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 CCD23891.1 - 0.0092 15.3 1.8 0.21 10.8 0.0 2.9 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase FGGY_C PF02782.16 CCD23891.1 - 0.14 11.9 0.0 0.57 9.9 0.0 2.0 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DUF5300 PF17224.3 CCD23891.1 - 0.47 10.7 4.5 14 6.0 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5300) DEAD PF00270.29 CCD23892.1 - 8e-48 162.5 0.1 3.6e-47 160.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD23892.1 - 4.7e-26 91.3 0.0 1.3e-25 89.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CCD23892.1 - 4.2e-20 71.7 0.0 8.7e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CCD23892.1 - 1.3e-05 25.2 0.0 1.3e-05 25.2 0.0 2.5 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 CCD23892.1 - 0.001 19.3 0.0 0.0029 17.8 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain PIN_6 PF17146.4 CCD23892.1 - 0.16 12.5 0.7 21 5.7 0.2 3.6 3 0 0 3 3 3 0 PIN domain of ribonuclease HORMA PF02301.18 CCD23893.1 - 1.6e-24 86.7 0.1 2.2e-24 86.3 0.1 1.2 1 0 0 1 1 1 1 HORMA domain DUF1682 PF07946.14 CCD23893.1 - 0.0034 16.7 0.1 0.0037 16.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) RRM_1 PF00076.22 CCD23894.1 - 8.3e-16 57.6 0.1 4.6e-09 36.0 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD23894.1 - 1.7e-05 24.8 0.3 0.00019 21.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif Vps8 PF12816.7 CCD23894.1 - 0.034 13.6 0.5 0.066 12.7 0.5 1.4 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 Bac_rhamnosid PF05592.11 CCD23894.1 - 0.089 12.8 0.1 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Acetyltransf_1 PF00583.25 CCD23895.1 - 1.7e-12 47.6 0.0 2.1e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCD23895.1 - 1.3e-06 28.4 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCD23895.1 - 3.7e-06 27.3 0.0 6.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CCD23895.1 - 0.0018 18.9 0.0 0.0023 18.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CCD23895.1 - 0.0062 16.7 0.0 0.0072 16.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CCD23895.1 - 0.013 15.6 0.1 0.033 14.3 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 CCD23895.1 - 0.06 13.1 0.1 0.3 10.8 0.0 2.1 1 1 2 3 3 3 0 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 CCD23895.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 CCD23895.1 - 0.12 12.4 0.1 0.38 10.8 0.1 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain NOC3p PF07540.11 CCD23896.1 - 2.3e-29 101.7 0.2 2.3e-29 101.7 0.2 3.0 3 1 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 CCD23896.1 - 1.2e-24 87.3 0.2 4.1e-24 85.5 0.2 2.0 1 0 0 1 1 1 1 CBF/Mak21 family Z1 PF10593.9 CCD23896.1 - 1.8 8.0 5.1 1.4 8.4 0.3 2.6 2 0 0 2 2 2 0 Z1 domain Candida_ALS_N PF11766.8 CCD23897.1 - 1.6e-72 243.7 4.6 1.6e-72 243.7 4.6 2.0 2 0 0 2 2 2 1 Cell-wall agglutinin N-terminal ligand-sugar binding Big_8 PF17961.1 CCD23897.1 - 0.006 16.7 0.0 0.026 14.7 0.0 2.0 1 0 0 1 1 1 1 Bacterial Ig domain DUF4674 PF15719.5 CCD23897.1 - 0.15 12.1 6.1 0.28 11.2 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) CMS1 PF14617.6 CCD23898.1 - 3.1e-18 66.0 11.3 1.3e-17 64.0 11.3 1.9 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Mt_ATP-synt_B PF05405.14 CCD23898.1 - 0.054 13.1 6.5 0.071 12.7 1.0 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SMC_Nse1 PF07574.13 CCD23899.1 - 8.4e-57 192.2 0.1 1.1e-56 191.8 0.1 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 CCD23899.1 - 7e-14 51.9 8.0 1.3e-13 51.0 8.0 1.5 1 0 0 1 1 1 1 RING-like domain DUF2161 PF09929.9 CCD23899.1 - 0.077 13.1 0.0 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) Ribosomal_L24e PF01246.20 CCD23900.1 - 2.3e-32 111.0 3.8 2.3e-32 111.0 3.8 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e DUF3629 PF12302.8 CCD23900.1 - 2.8 7.3 9.9 3 7.2 9.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3629) Proteasome PF00227.26 CCD23902.1 - 4.1e-46 156.9 1.1 4.7e-46 156.7 1.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Sfi1 PF08457.10 CCD23903.1 - 1.6e-22 79.8 71.8 1.7e-22 79.7 45.2 3.1 1 1 2 3 3 3 3 Sfi1 spindle body protein Sfi1_C PF10638.9 CCD23903.1 - 1.2e-20 74.2 2.2 1.2e-20 74.2 2.2 4.3 5 1 1 6 6 6 1 Spindle body associated protein C-terminus IL17R_D_N PF16742.5 CCD23903.1 - 0.017 15.2 0.1 0.05 13.7 0.1 1.8 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Ribophorin_I PF04597.14 CCD23904.1 - 1e-120 404.0 2.9 1.1e-120 403.8 2.9 1.0 1 0 0 1 1 1 1 Ribophorin I ORC_WH_C PF18137.1 CCD23905.1 - 2.9e-20 72.8 0.3 1.5e-19 70.4 0.0 2.2 2 0 0 2 2 2 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 CCD23905.1 - 3.3e-05 23.1 6.1 0.00014 21.1 6.1 1.9 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus RSN1_7TM PF02714.15 CCD23906.1 - 5.3e-71 239.1 24.0 5.3e-71 239.1 24.0 2.5 4 0 0 4 4 4 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CCD23906.1 - 1.1e-27 96.7 0.6 1.1e-27 96.7 0.6 2.9 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CCD23906.1 - 0.0001 22.6 3.1 0.00026 21.3 3.1 1.9 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter MMM1 PF10296.9 CCD23907.1 - 6.2e-135 449.5 3.8 7.4e-135 449.3 3.8 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 PH_12 PF16457.5 CCD23908.1 - 1.2e-09 38.7 4.4 0.00096 19.7 0.1 3.4 3 0 0 3 3 3 2 Pleckstrin homology domain DUF5331 PF17265.2 CCD23908.1 - 0.067 12.9 0.4 0.44 10.3 0.0 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5331) DEAD PF00270.29 CCD23909.1 - 3.6e-47 160.4 0.2 8.2e-47 159.2 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD23909.1 - 1e-31 109.5 0.4 1.8e-29 102.3 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 CCD23909.1 - 0.057 13.8 0.6 0.34 11.2 0.6 2.3 1 1 0 1 1 1 0 AAA domain COX17 PF05051.13 CCD23910.1 - 3.1e-21 75.5 6.3 3.8e-21 75.2 6.3 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 CCD23910.1 - 0.00034 20.6 4.7 0.015 15.3 0.1 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 CCD23910.1 - 0.0041 17.2 3.5 0.0063 16.6 3.5 1.4 1 0 0 1 1 1 1 CHCH domain DPPIV_N PF00930.21 CCD23911.1 - 2.4e-103 345.6 3.3 3.5e-103 345.1 3.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CCD23911.1 - 2.3e-50 171.0 1.1 3.9e-50 170.3 1.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CCD23911.1 - 0.0012 19.5 0.0 0.01 16.5 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 CCD23911.1 - 0.067 12.8 0.6 0.26 10.9 0.3 1.9 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 CCD23911.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thiolase_N PF00108.23 CCD23912.1 - 2.9e-80 269.4 0.0 3.8e-80 269.0 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CCD23912.1 - 2.9e-48 162.6 0.5 5.4e-48 161.7 0.5 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CCD23912.1 - 0.0012 18.5 0.1 0.0037 16.9 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ThiF PF00899.21 CCD23913.1 - 2.2e-112 374.3 0.0 1.5e-77 260.2 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CCD23913.1 - 3e-89 299.3 1.4 4.5e-89 298.7 1.4 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 CCD23913.1 - 1.1e-32 112.6 0.0 3.2e-32 111.1 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 CCD23913.1 - 1.3e-27 95.8 0.4 3e-27 94.6 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 CCD23913.1 - 9e-25 86.7 0.6 2.4e-24 85.3 0.6 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Gly_transf_sug PF04488.15 CCD23914.1 - 1.2e-10 41.9 0.0 4e-10 40.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif BBP1_C PF15272.6 CCD23914.1 - 0.0024 17.7 0.8 0.0043 16.9 0.8 1.4 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal DUF16 PF01519.16 CCD23914.1 - 0.012 16.1 5.0 0.028 14.9 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Septin PF00735.18 CCD23916.1 - 2.8e-104 348.4 0.1 6.5e-104 347.1 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CCD23916.1 - 4e-07 30.1 0.0 9.9e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CCD23916.1 - 0.00017 21.0 0.0 0.00017 21.0 0.0 2.3 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 CCD23916.1 - 0.00018 21.5 0.7 0.00018 21.5 0.7 3.0 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 CCD23916.1 - 0.0003 21.3 0.7 0.0016 18.9 0.0 2.1 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.23 CCD23916.1 - 0.002 18.2 8.0 0.0075 16.3 0.2 3.0 2 2 1 3 3 3 2 Dynamin family IIGP PF05049.13 CCD23916.1 - 0.0025 16.9 0.1 0.0049 16.0 0.1 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 CCD23916.1 - 0.014 14.9 0.3 0.094 12.2 0.3 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 CCD23916.1 - 0.088 12.6 0.3 2.4 7.9 0.1 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 CCD23916.1 - 1.7 9.1 16.3 8.9 6.7 12.0 2.4 2 0 0 2 2 2 0 AAA domain IGPS PF00218.21 CCD23917.1 - 8.2e-91 303.7 1.4 1.3e-90 303.0 1.4 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 CCD23917.1 - 6.2e-48 163.1 0.0 1.1e-47 162.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CCD23917.1 - 1.5e-08 34.6 0.5 5.9e-08 32.7 0.5 2.0 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 CCD23917.1 - 0.0076 16.0 0.3 0.019 14.7 0.3 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain DUF1040 PF06288.13 CCD23917.1 - 0.023 15.1 0.6 0.089 13.2 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1040) Syja_N PF02383.18 CCD23918.1 - 3.5e-82 276.3 2.8 4.7e-82 275.9 2.8 1.2 1 0 0 1 1 1 1 SacI homology domain Meiosis_expr PF15163.6 CCD23918.1 - 0.17 12.5 0.4 0.62 10.8 0.4 2.0 1 0 0 1 1 1 0 Meiosis-expressed Ribosomal_L30 PF00327.20 CCD23919.1 - 2.3e-12 46.6 1.1 5.6e-12 45.4 1.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e WD40 PF00400.32 CCD23920.1 - 1.9e-41 139.2 15.0 6e-11 42.7 0.1 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD23920.1 - 8.1e-14 51.7 3.2 0.031 14.6 0.0 5.7 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCD23920.1 - 9e-10 37.8 9.1 0.0085 14.8 0.1 4.9 2 1 1 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CCD23920.1 - 1.2e-06 27.6 0.5 0.081 11.7 0.0 3.3 1 1 1 3 3 3 2 Nup133 N terminal like Ge1_WD40 PF16529.5 CCD23920.1 - 2.8e-06 26.5 1.2 0.41 9.5 0.0 4.8 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CCD23920.1 - 0.00052 18.7 0.0 0.05 12.1 0.0 2.1 1 1 0 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.6 CCD23920.1 - 0.00064 19.1 0.3 0.68 9.2 0.2 2.8 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 CCD23920.1 - 0.0098 14.3 0.0 0.03 12.6 0.0 1.7 2 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 CCD23920.1 - 0.017 14.1 2.8 0.083 11.8 0.0 3.1 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain DnaJ_C PF01556.18 CCD23921.1 - 1.5e-36 125.7 0.1 1.9e-36 125.3 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCD23921.1 - 4.9e-24 84.2 0.5 7.8e-24 83.6 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain Malate_DH PF12434.8 CCD23921.1 - 0.29 11.2 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Forkhead_N PF08430.12 CCD23921.1 - 0.35 11.5 8.8 0.69 10.5 8.8 1.4 1 0 0 1 1 1 0 Forkhead N-terminal region Pirin PF02678.16 CCD23922.1 - 2.2e-26 91.9 0.5 4.4e-26 91.0 0.4 1.5 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 CCD23922.1 - 3.2e-14 53.1 0.0 1.3e-13 51.2 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 CCD23922.1 - 0.0026 17.5 0.4 0.0026 17.5 0.4 1.7 2 0 0 2 2 2 1 Cupin domain Alg6_Alg8 PF03155.15 CCD23923.1 - 2.1e-146 488.7 27.1 2.6e-146 488.4 27.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Cyclin PF08613.11 CCD23924.1 - 4.8e-28 98.5 2.5 4.8e-28 98.5 2.5 2.5 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CCD23924.1 - 0.00017 21.4 0.1 0.00031 20.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Maf1 PF09174.10 CCD23924.1 - 0.19 11.9 4.6 0.15 12.2 0.1 2.6 2 1 0 2 2 2 0 Maf1 regulator DHHC PF01529.20 CCD23925.1 - 1.4e-30 106.1 14.8 1.4e-30 106.1 14.8 2.3 3 0 0 3 3 3 1 DHHC palmitoyltransferase Sin3a_C PF16879.5 CCD23926.1 - 2.4e-79 267.0 7.1 2.4e-79 267.0 7.1 3.7 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 CCD23926.1 - 1.2e-43 147.1 0.1 7.9e-43 144.5 0.1 2.6 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 CCD23926.1 - 2.2e-42 142.9 14.2 4.9e-16 58.6 1.9 4.8 4 0 0 4 4 4 3 Paired amphipathic helix repeat RNA_pol_L_2 PF13656.6 CCD23927.1 - 5.2e-24 83.8 0.0 6.9e-24 83.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CCD23927.1 - 8.2e-08 31.6 0.0 1.8e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.25 CCD23928.1 - 1.1e-72 244.6 0.9 1.3e-72 244.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD23928.1 - 1.2e-39 136.2 0.0 2e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CCD23928.1 - 1.2e-26 92.6 0.0 7.9e-14 51.6 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 CCD23928.1 - 2.2e-09 37.1 0.0 5.6e-08 32.4 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CCD23928.1 - 0.00046 19.1 0.3 0.00046 19.1 0.3 2.0 2 1 0 2 2 2 1 Fungal protein kinase SH3_3 PF08239.11 CCD23928.1 - 0.0036 17.5 0.1 0.0082 16.4 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Kdo PF06293.14 CCD23928.1 - 0.019 14.3 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5386 PF17360.2 CCD23928.1 - 0.063 13.2 0.0 0.25 11.2 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5386) APH PF01636.23 CCD23928.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Topoisom_I PF01028.20 CCD23929.1 - 6.1e-97 323.4 1.4 6.1e-97 323.4 1.4 3.0 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 CCD23929.1 - 9.4e-96 319.4 0.4 9.4e-96 319.4 0.4 3.9 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 CCD23929.1 - 2.9e-33 113.6 0.6 1.3e-32 111.5 0.6 2.3 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF2207 PF09972.9 CCD23930.1 - 8.9e-05 21.4 0.6 0.00015 20.7 0.1 1.6 1 1 0 2 2 2 1 Predicted membrane protein (DUF2207) Transformer PF06495.11 CCD23930.1 - 0.023 14.8 4.0 0.14 12.2 4.4 2.0 2 0 0 2 2 2 0 Fruit fly transformer protein Polyketide_cyc PF03364.20 CCD23931.1 - 1.2e-17 64.3 0.0 1.7e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF2883 PF11097.8 CCD23931.1 - 0.22 11.7 1.3 0.3 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2883) MMM1 PF10296.9 CCD23932.1 - 2.5e-06 26.8 0.2 3.6e-06 26.3 0.2 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 PX PF00787.24 CCD23933.1 - 7.2e-20 71.1 1.0 1.4e-19 70.1 0.2 2.0 2 0 0 2 2 2 1 PX domain TSNAXIP1_N PF15739.5 CCD23933.1 - 0.0035 17.7 1.9 0.062 13.7 0.4 2.7 2 0 0 2 2 2 1 Translin-associated factor X-interacting N-terminus RTC PF01137.21 CCD23934.1 - 2.5e-46 157.7 0.0 2.9e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CCD23934.1 - 1.6e-32 112.1 0.0 2.7e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PLA2_B PF01735.18 CCD23935.1 - 4.8e-210 698.1 13.8 4.8e-210 698.1 13.8 2.1 2 1 0 2 2 2 1 Lysophospholipase catalytic domain DUF3051 PF11252.8 CCD23935.1 - 0.022 14.5 0.7 0.075 12.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3051) PBP1_TM PF14812.6 CCD23935.1 - 0.29 11.5 7.1 0.072 13.5 2.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 CCD23935.1 - 0.7 10.3 7.5 1.3 9.4 2.5 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 CCD23935.1 - 10 6.5 8.7 3.3 8.0 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Histone PF00125.24 CCD23936.1 - 7.2e-18 65.2 0.0 9.1e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CCD23936.1 - 1.4e-12 47.1 0.7 2.2e-12 46.5 0.7 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CCD23936.1 - 0.00033 20.9 0.0 0.00047 20.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-RING_2 PF13639.6 CCD23937.1 - 1e-09 38.6 2.7 1e-09 38.6 2.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CCD23937.1 - 8.8e-06 25.9 7.9 2.2e-05 24.6 7.9 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CCD23937.1 - 7.1e-05 22.6 4.7 7.7e-05 22.5 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCD23937.1 - 9.3e-05 22.2 7.2 0.00042 20.1 7.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCD23937.1 - 0.00011 22.0 0.6 0.00027 20.7 0.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CCD23937.1 - 0.00013 21.8 6.2 0.00045 20.1 6.4 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CCD23937.1 - 0.00025 20.8 5.1 0.00025 20.8 5.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CCD23937.1 - 0.0021 17.6 0.4 0.0044 16.6 0.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 CCD23937.1 - 0.0071 16.4 5.6 0.0071 16.4 5.6 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 CCD23937.1 - 0.13 12.0 6.6 0.13 12.1 0.4 2.9 3 0 0 3 3 3 0 RING-like zinc finger zf-ANAPC11 PF12861.7 CCD23937.1 - 0.17 12.0 3.3 0.094 12.8 1.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger BNIP2 PF12496.8 CCD23937.1 - 0.25 11.8 0.1 0.25 11.8 0.1 3.0 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 zf-C3HC4_4 PF15227.6 CCD23937.1 - 0.31 11.2 6.8 0.051 13.7 1.7 2.4 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 CCD23937.1 - 1.7 8.8 4.8 23 5.2 2.7 2.8 1 1 2 3 3 3 0 FANCL C-terminal domain RINGv PF12906.7 CCD23937.1 - 1.9 8.7 6.1 0.27 11.4 1.6 1.8 2 0 0 2 2 2 0 RING-variant domain CTU2 PF10288.9 CCD23937.1 - 7.7 6.8 7.9 9.6 6.5 3.3 2.8 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Ribonuc_red_sm PF00268.21 CCD23938.1 - 4.5e-116 387.2 2.3 5.9e-116 386.8 2.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 CCD23938.1 - 0.16 12.8 0.0 0.41 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) HSP20 PF00011.21 CCD23939.1 - 4.2e-18 65.4 1.0 5.5e-18 65.0 1.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CCD23939.1 - 0.00019 20.9 0.0 0.00043 19.8 0.0 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DNA_pol_E_B PF04042.16 CCD23940.1 - 1.2e-43 148.9 0.0 2e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CCD23940.1 - 8.7e-37 126.1 0.0 1.6e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain SH3_1 PF00018.28 CCD23943.1 - 7.6e-09 35.0 0.2 1.9e-08 33.8 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CCD23943.1 - 2e-08 33.8 0.0 4.4e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CCD23943.1 - 1.9e-07 30.8 0.3 5.7e-07 29.3 0.3 1.9 1 0 0 1 1 1 1 Variant SH3 domain Sad1_UNC PF07738.13 CCD23944.1 - 7.5e-06 26.0 2.9 0.0054 16.7 1.4 3.0 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal Efg1 PF10153.9 CCD23944.1 - 0.12 12.7 1.0 0.28 11.5 1.0 1.6 1 0 0 1 1 1 0 rRNA-processing protein Efg1 Rep_1 PF01446.17 CCD23945.1 - 0.097 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Replication protein Thi4 PF01946.17 CCD23946.1 - 2.1e-103 344.6 0.1 2.5e-103 344.4 0.1 1.0 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CCD23946.1 - 2.6e-07 30.5 0.5 1e-06 28.6 0.3 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CCD23946.1 - 7.9e-07 28.6 0.3 2.1e-05 23.9 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CCD23946.1 - 5.3e-06 26.6 0.0 1.6e-05 25.0 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CCD23946.1 - 9.3e-06 25.0 0.5 0.0003 20.0 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 CCD23946.1 - 6.5e-05 23.0 0.1 0.00035 20.6 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 CCD23946.1 - 0.00054 19.4 0.0 0.00074 19.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CCD23946.1 - 0.00067 18.8 0.1 0.00085 18.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 CCD23946.1 - 0.0018 17.1 0.2 0.003 16.3 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 CCD23946.1 - 0.0033 16.7 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF_assoc_1 PF08355.12 CCD23946.1 - 0.023 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 EF hand associated GIDA PF01134.22 CCD23946.1 - 0.023 13.8 0.4 0.059 12.4 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A K_oxygenase PF13434.6 CCD23946.1 - 0.059 12.5 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 CCD23946.1 - 0.16 10.8 0.1 0.23 10.3 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase ILVD_EDD PF00920.21 CCD23947.1 - 9e-207 687.8 0.2 1e-206 687.6 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family CTP_transf_like PF01467.26 CCD23948.1 - 8.9e-35 120.0 0.0 1.9e-34 118.9 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like Rotamase PF00639.21 CCD23949.1 - 4e-28 98.2 0.1 5.8e-28 97.7 0.1 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CCD23949.1 - 1e-21 77.6 0.0 1.5e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 CCD23949.1 - 1.2e-08 34.9 2.3 2.5e-08 33.8 2.3 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 CCD23949.1 - 1.7e-07 32.1 0.0 2.5e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 CCD23949.1 - 0.16 12.7 0.0 0.3 11.8 0.0 1.4 1 0 0 1 1 1 0 X8 domain Acyl_CoA_thio PF02551.15 CCD23950.1 - 6e-47 158.8 3.6 1.5e-34 118.7 1.4 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.6 CCD23950.1 - 4.4e-36 125.4 0.0 1e-35 124.2 0.0 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily DUF3533 PF12051.8 CCD23951.1 - 1.6e-122 409.1 26.4 2.1e-122 408.7 26.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Fst_toxin PF13955.6 CCD23951.1 - 0.091 12.7 0.2 0.21 11.5 0.2 1.6 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system DUF1387 PF07139.11 CCD23951.1 - 2.2 7.9 8.3 3.6 7.2 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SUI1 PF01253.22 CCD23952.1 - 3.1e-21 75.7 1.9 4.1e-21 75.3 1.3 1.5 1 1 0 1 1 1 1 Translation initiation factor SUI1 Cu PF17563.2 CCD23952.1 - 0.73 10.1 7.3 7.4 6.9 0.5 2.5 2 0 0 2 2 2 0 Cupiennin RNase_PH PF01138.21 CCD23953.1 - 7.8e-26 91.1 0.0 1.1e-25 90.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CCD23953.1 - 2.2e-05 24.4 0.1 4.7e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Gp_dh_C PF02800.20 CCD23954.1 - 5.4e-72 240.5 0.0 9.4e-72 239.8 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CCD23954.1 - 3.2e-38 130.1 0.0 7.4e-38 129.0 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CCD23954.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AA_permease PF00324.21 CCD23955.1 - 4.5e-136 454.2 31.8 5.6e-136 453.9 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD23955.1 - 7.3e-39 133.8 34.5 9e-39 133.5 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease EIF_2_alpha PF07541.12 CCD23956.1 - 1.8e-38 131.2 0.9 3.1e-38 130.5 0.2 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CCD23956.1 - 2.6e-14 53.3 2.0 4.9e-14 52.4 1.0 1.9 2 0 0 2 2 2 1 S1 RNA binding domain Troponin PF00992.20 CCD23956.1 - 0.0023 18.2 0.7 0.0051 17.1 0.7 1.5 1 0 0 1 1 1 1 Troponin EXOSC1 PF10447.9 CCD23956.1 - 0.11 13.1 1.2 0.22 12.1 0.3 2.0 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 Memo PF01875.17 CCD23957.1 - 3.5e-92 308.4 0.2 4e-92 308.2 0.2 1.0 1 0 0 1 1 1 1 Memo-like protein Mannosyl_trans PF05007.13 CCD23958.1 - 3.3e-85 286.1 28.0 4.3e-85 285.7 28.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 CCD23958.1 - 1.6e-09 37.4 29.0 6.8e-09 35.3 29.0 1.8 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 CCD23958.1 - 2.1e-08 34.2 1.6 2.1e-08 34.2 1.6 2.1 1 1 0 2 2 2 1 Glycosyltransferase family 87 DUF5572 PF17733.1 CCD23959.1 - 4.7e-10 39.1 0.2 8.9e-10 38.3 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) SPC12 PF06645.13 CCD23961.1 - 1e-23 83.1 0.5 1.3e-23 82.9 0.5 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ATP-sulfurylase PF01747.17 CCD23962.1 - 7.3e-87 290.3 0.0 9.4e-87 289.9 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 CCD23962.1 - 3.1e-48 163.5 0.0 4.7e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain CTP_transf_like PF01467.26 CCD23962.1 - 0.066 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Cytidylyltransferase-like Glyco_hydro_16 PF00722.21 CCD23963.1 - 7.3e-45 152.6 1.1 7.3e-45 152.6 1.1 2.3 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 RNA_pol_Rpb4 PF03874.16 CCD23964.1 - 2e-29 102.4 7.6 2.9e-29 101.9 7.6 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Rer1 PF03248.13 CCD23964.1 - 0.099 12.4 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Rer1 family VTC PF09359.10 CCD23965.1 - 3.1e-101 338.4 2.4 4.2e-101 338.0 0.0 1.9 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 CCD23965.1 - 4.1e-11 43.4 12.3 7.3e-06 26.1 1.0 3.4 2 1 1 3 3 3 3 SPX domain DUF202 PF02656.15 CCD23965.1 - 1.4e-08 35.0 3.8 1.4e-08 35.0 3.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Mad3_BUB1_I PF08311.12 CCD23966.1 - 4.2e-38 130.1 1.0 1e-37 128.9 1.0 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 CCD23966.1 - 1.2e-22 79.9 1.2 3e-22 78.6 0.2 2.3 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Mad3_BUB1_I_2 PF17014.5 CCD23966.1 - 0.014 15.6 0.3 0.037 14.2 0.3 1.7 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Mer2 PF09074.10 CCD23967.1 - 6.8e-67 225.0 25.4 6.8e-67 225.0 25.4 1.7 2 0 0 2 2 2 1 Mer2 DUF1351 PF07083.11 CCD23967.1 - 0.035 13.9 9.2 0.072 12.9 9.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) Cep57_MT_bd PF06657.13 CCD23967.1 - 0.15 12.5 6.4 3.2 8.3 3.4 3.0 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Mem_trans PF03547.18 CCD23967.1 - 0.37 9.1 4.3 0.49 8.7 4.3 1.2 1 0 0 1 1 1 0 Membrane transport protein Fib_alpha PF08702.10 CCD23967.1 - 1.8 8.8 21.9 1.6 8.9 13.9 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family BPL_N PF09825.9 CCD23967.1 - 3.2 6.7 6.9 4.9 6.1 6.9 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF2959 PF11172.8 CCD23967.1 - 4.1 7.5 12.9 2.5 8.2 2.2 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF2959) ID PF18543.1 CCD23967.1 - 5.3 7.1 5.6 1.1 9.3 1.0 2.1 2 0 0 2 2 2 0 Intracellular delivery domain KxDL PF10241.9 CCD23967.1 - 7.2 7.0 14.1 0.28 11.5 4.2 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein LSM PF01423.22 CCD23968.1 - 3e-09 36.4 1.6 3.1e-09 36.4 0.1 1.7 2 0 0 2 2 2 1 LSM domain Aldolase_II PF00596.21 CCD23969.1 - 2.1e-42 145.2 0.0 2.6e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HEAT PF02985.22 CCD23970.1 - 0.0015 18.6 0.2 2.3 8.7 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Vac14_Fab1_bd PF12755.7 CCD23970.1 - 0.009 16.6 0.0 4.6 7.9 0.0 2.7 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region Thrombin_light PF09396.10 CCD23970.1 - 0.014 15.2 0.1 0.055 13.2 0.1 2.0 1 0 0 1 1 1 0 Thrombin light chain TPP_enzyme_N PF02776.18 CCD23971.1 - 5.9e-33 113.9 0.0 1.1e-32 113.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCD23971.1 - 1.1e-27 96.4 0.0 4.2e-27 94.5 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCD23971.1 - 1.1e-14 54.5 0.0 2.1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF3234 PF11572.8 CCD23971.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3234) Gp_dh_C PF02800.20 CCD23972.1 - 4.1e-72 240.9 0.1 6.2e-72 240.3 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CCD23972.1 - 2.7e-39 133.6 0.3 6.1e-39 132.4 0.1 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CCD23972.1 - 0.051 12.9 0.1 0.1 11.9 0.1 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 CCD23972.1 - 0.081 13.0 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ribosomal_S2 PF00318.20 CCD23973.1 - 9.1e-25 87.2 0.3 1.4e-13 50.6 0.0 2.4 2 1 1 3 3 3 2 Ribosomal protein S2 40S_SA_C PF16122.5 CCD23973.1 - 0.054 14.8 12.2 0.11 13.8 12.2 1.6 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus Ferric_reduct PF01794.19 CCD23974.1 - 4.9e-21 75.1 6.0 4.9e-21 75.1 6.0 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CCD23974.1 - 0.0039 17.3 0.1 0.0097 16.0 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain AA_permease_2 PF13520.6 CCD23975.1 - 2.8e-62 210.9 41.2 3.5e-62 210.6 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCD23975.1 - 2.4e-13 49.5 37.9 4.2e-13 48.7 37.9 1.3 1 1 0 1 1 1 1 Amino acid permease DUF2456 PF10445.9 CCD23975.1 - 0.9 9.6 9.6 3.5 7.8 0.7 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2456) CRM1_C PF08767.11 CCD23976.1 - 3.2e-74 250.0 17.6 3.2e-74 250.0 17.6 3.5 6 0 0 6 6 6 1 CRM1 C terminal Xpo1 PF08389.12 CCD23976.1 - 6.1e-29 101.0 4.8 6.1e-29 101.0 4.8 4.6 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 CCD23976.1 - 7.5e-14 51.4 3.7 8e-14 51.3 0.5 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain CRM1_repeat_3 PF18787.1 CCD23976.1 - 7.4e-12 45.2 0.5 5.9e-11 42.3 0.2 2.7 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat_2 PF18784.1 CCD23976.1 - 4.9e-11 42.1 1.4 1.9e-10 40.3 1.4 2.1 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat PF18777.1 CCD23976.1 - 0.00022 20.7 0.2 0.00083 18.8 0.2 2.1 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat PAH PF02671.21 CCD23976.1 - 0.028 14.6 0.1 0.35 11.0 0.0 2.9 2 0 0 2 2 2 0 Paired amphipathic helix repeat Ribosomal_L6 PF00347.23 CCD23977.1 - 1.5e-20 73.6 2.3 3.8e-09 37.1 0.2 2.7 2 1 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S4 PF00163.19 CCD23978.1 - 1.1e-13 51.9 2.0 1.8e-13 51.2 1.9 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 CCD23978.1 - 3.4e-13 49.1 0.0 3.1e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 S4 domain Herpes_LAMP2 PF06126.11 CCD23978.1 - 0.043 12.5 0.1 0.051 12.2 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Baculo_gp41 PF04700.12 CCD23978.1 - 0.063 13.0 0.2 0.087 12.6 0.2 1.2 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region Pox_A_type_inc PF04508.12 CCD23978.1 - 0.51 10.3 2.2 1 9.3 0.6 2.3 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat SKG6 PF08693.10 CCD23979.1 - 5.1e-16 57.8 7.2 1.2e-15 56.6 7.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 CCD23979.1 - 6.4e-06 26.1 0.0 6.4e-06 26.1 0.0 3.7 3 1 0 3 3 3 1 TMEM154 protein family DUF4448 PF14610.6 CCD23979.1 - 0.00046 20.0 5.0 0.0014 18.5 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF4448) m04gp34like PF12216.8 CCD23979.1 - 0.019 14.6 0.0 0.065 12.8 0.0 2.0 1 0 0 1 1 1 0 Immune evasion protein EphA2_TM PF14575.6 CCD23979.1 - 0.048 14.5 0.4 0.42 11.5 0.0 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 CCD23979.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.5 4 1 1 5 5 5 0 Orf78 (ac78) RIFIN PF02009.16 CCD23979.1 - 9.4 6.0 7.8 0.85 9.5 0.4 2.4 2 0 0 2 2 2 0 Rifin Pex24p PF06398.11 CCD23980.1 - 1.7e-63 214.9 0.2 2.5e-63 214.3 0.2 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Reticulon PF02453.17 CCD23980.1 - 0.00063 19.7 0.0 0.27 11.2 0.0 2.3 2 0 0 2 2 2 2 Reticulon PRT_C PF08372.10 CCD23980.1 - 0.034 13.9 4.8 0.14 11.9 0.5 3.0 3 1 0 3 3 3 0 Plant phosphoribosyltransferase C-terminal Lectin_C PF00059.21 CCD23981.1 - 0.31 11.8 3.2 15 6.4 2.7 2.9 2 1 0 2 2 2 0 Lectin C-type domain Spo12 PF05032.12 CCD23982.1 - 4.7e-17 61.6 2.9 4.7e-17 61.6 2.9 2.4 2 1 1 3 3 3 1 Spo12 family RTT107_BRCT_6 PF16771.5 CCD23983.1 - 2.4e-38 130.8 3.9 2.4e-38 130.8 3.9 4.7 5 1 0 5 5 5 1 Regulator of Ty1 transposition protein 107 BRCT domain RTT107_BRCT_5 PF16770.5 CCD23983.1 - 1.2e-20 73.3 6.6 6.2e-19 67.7 0.0 5.3 5 1 1 6 6 6 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 CCD23983.1 - 4.1e-20 71.5 2.3 1.3e-13 50.7 0.1 3.9 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 CCD23983.1 - 2.6e-18 66.2 23.5 7.8e-08 32.6 0.3 6.3 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CCD23983.1 - 1.9e-11 44.2 14.1 0.00084 19.7 0.2 5.7 5 0 0 5 5 5 3 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 CCD23983.1 - 7.2e-06 26.0 0.4 0.032 14.3 0.0 4.2 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CCD23983.1 - 0.00028 21.1 0.7 0.26 11.6 0.0 3.9 4 0 0 4 4 4 1 DNA ligase 3 BRCT domain Nramp PF01566.18 CCD23984.1 - 0.034 13.1 0.0 0.038 13.0 0.0 1.0 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein Inhibitor_I53 PF11714.8 CCD23984.1 - 0.046 13.9 0.0 0.057 13.6 0.0 1.2 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Z1 PF10593.9 CCD23985.1 - 3.4 7.1 8.7 8.3 5.8 8.7 1.7 1 1 0 1 1 1 0 Z1 domain TDA11 PF17084.5 CCD23986.1 - 2.7e-49 168.4 47.2 7.6e-44 150.4 47.2 4.2 1 1 0 1 1 1 1 Topoisomerase I damage affected protein 11 SVIP PF15811.5 CCD23986.1 - 0.23 11.9 7.0 0.89 10.1 7.0 2.0 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Ly49 PF08391.10 CCD23986.1 - 2.1 8.7 9.9 0.27 11.6 2.5 2.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region TGFb_propeptide PF00688.18 CCD23987.1 - 0.011 15.5 1.2 0.019 14.7 1.2 1.3 1 0 0 1 1 1 0 TGF-beta propeptide SRI PF08236.11 CCD23987.1 - 0.029 14.5 0.3 0.19 11.9 0.1 2.3 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Folliculin_C PF16692.5 CCD23987.1 - 0.032 13.9 0.2 0.051 13.3 0.2 1.4 1 0 0 1 1 1 0 Folliculin C-terminal domain SepQ PF06622.11 CCD23987.1 - 0.054 12.6 0.2 0.082 12.0 0.2 1.3 1 0 0 1 1 1 0 SepQ protein DUF3138 PF11336.8 CCD23987.1 - 0.083 11.5 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ANTH PF07651.16 CCD23988.1 - 3.4e-62 210.0 1.9 3.4e-62 210.0 1.9 1.9 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 CCD23988.1 - 0.00018 21.5 0.5 0.0007 19.6 0.1 2.3 2 0 0 2 2 2 1 ENTH domain MPC PF03650.13 CCD23989.1 - 2.4e-46 156.4 0.0 3.3e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DDE_1 PF03184.19 CCD23990.1 - 3.5e-06 26.8 0.1 1.3e-05 24.9 0.1 2.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Glucosamine_iso PF01182.20 CCD23991.1 - 3.7e-58 197.1 0.0 4.6e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Dna2 PF08696.11 CCD23992.1 - 6.4e-55 186.1 0.2 1.6e-54 184.8 0.0 1.8 2 0 0 2 2 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 CCD23992.1 - 8.2e-51 172.5 1.4 1e-50 172.1 0.3 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CCD23992.1 - 1.1e-29 104.0 0.0 1.1e-14 54.9 0.0 2.8 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 CCD23992.1 - 3.7e-11 43.1 0.0 9.7e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCD23992.1 - 3.4e-10 40.5 0.0 8e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 CCD23992.1 - 9.1e-07 29.0 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 CCD23992.1 - 1.7e-06 27.9 3.7 0.0076 16.0 0.0 4.1 5 0 0 5 5 3 2 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.17 CCD23992.1 - 0.00028 21.0 0.1 0.00098 19.3 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function DUF83 AAA_18 PF13238.6 CCD23992.1 - 0.00059 20.4 0.1 0.0036 17.8 0.0 2.4 2 0 0 2 2 1 1 AAA domain UvrD-helicase PF00580.21 CCD23992.1 - 0.002 17.7 0.4 0.0081 15.7 0.0 2.4 3 0 0 3 3 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 CCD23992.1 - 0.0047 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CCD23992.1 - 0.006 17.0 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 CCD23992.1 - 0.013 15.1 0.0 0.059 13.0 0.0 2.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 CCD23992.1 - 0.018 14.9 0.1 0.29 11.0 0.0 2.8 3 0 0 3 3 3 0 NTPase AAA_33 PF13671.6 CCD23992.1 - 0.02 15.0 0.0 0.096 12.8 0.0 2.2 2 0 0 2 2 1 0 AAA domain Arf PF00025.21 CCD23992.1 - 0.027 13.9 0.0 0.066 12.7 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_22 PF13401.6 CCD23992.1 - 0.028 14.7 0.4 0.25 11.6 0.0 2.9 3 1 0 3 3 2 0 AAA domain Helicase_RecD PF05127.14 CCD23992.1 - 0.033 14.1 0.0 0.15 11.9 0.0 2.1 1 1 0 1 1 1 0 Helicase AAA_29 PF13555.6 CCD23992.1 - 0.071 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CCD23992.1 - 0.074 12.6 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region PEPCK_ATP PF01293.20 CCD23992.1 - 0.081 11.6 0.0 0.95 8.1 0.0 2.1 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase MobB PF03205.14 CCD23992.1 - 0.083 12.8 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.6 CCD23992.1 - 0.085 13.3 0.0 0.41 11.1 0.0 2.3 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 CCD23992.1 - 0.091 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.15 CCD23992.1 - 0.093 12.7 0.1 0.42 10.6 0.0 2.3 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 CCD23992.1 - 0.098 12.7 0.1 0.93 9.5 0.1 2.9 1 1 0 1 1 1 0 AAA domain Terminase_6 PF03237.15 CCD23992.1 - 0.16 11.6 0.0 0.4 10.3 0.0 1.7 1 0 0 1 1 1 0 Terminase-like family AAA_5 PF07728.14 CCD23992.1 - 0.23 11.5 1.0 0.6 10.1 0.0 2.2 3 0 0 3 3 1 0 AAA domain (dynein-related subfamily) PRIMA1 PF16101.5 CCD23993.1 - 1.4 9.0 5.5 3.6 7.7 5.5 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PROCN PF08083.11 CCD23994.1 - 2.6e-223 741.1 14.1 4e-223 740.5 14.1 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CCD23994.1 - 4.8e-122 405.9 0.4 1e-121 404.9 0.4 1.6 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CCD23994.1 - 7e-85 282.8 1.2 7e-85 282.8 1.2 2.1 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 CCD23994.1 - 3.8e-77 257.4 2.2 8.4e-77 256.3 2.2 1.6 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CCD23994.1 - 8.3e-70 233.1 0.0 2.2e-69 231.7 0.0 1.8 2 0 0 2 2 2 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 CCD23994.1 - 2.9e-48 162.8 0.0 6.8e-48 161.7 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 CCD23994.1 - 1.4e-45 153.5 0.9 4e-45 152.1 0.9 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 CCD23994.1 - 0.00088 19.2 0.2 0.0033 17.4 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ANAPC8 PF04049.13 CCD23995.1 - 2.6e-38 131.2 0.0 6.1e-38 130.0 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 CCD23995.1 - 1e-23 81.5 18.5 1.2e-05 25.2 0.0 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 CCD23995.1 - 3e-22 77.5 16.1 1.1e-05 25.1 0.0 8.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 CCD23995.1 - 1.1e-21 75.1 15.0 0.00086 19.2 0.0 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 CCD23995.1 - 1.4e-15 56.6 0.1 0.00043 20.9 0.0 7.7 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 CCD23995.1 - 5e-09 35.7 5.8 5.6e-09 35.6 0.1 3.7 3 2 2 5 5 4 1 TPR repeat TPR_16 PF13432.6 CCD23995.1 - 5.3e-08 33.4 0.1 1.2e-05 25.8 0.0 4.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCD23995.1 - 1.8e-07 30.7 1.2 0.53 10.4 0.0 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat ChAPs PF09295.10 CCD23995.1 - 1.2e-06 27.8 0.0 3.7e-05 22.9 0.0 2.2 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 CCD23995.1 - 2.3e-06 27.7 0.0 0.65 10.2 0.0 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD23995.1 - 2.9e-06 27.4 19.4 0.012 15.8 0.2 5.4 2 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CCD23995.1 - 3.6e-06 27.0 8.5 0.0015 18.8 0.0 6.7 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCD23995.1 - 2.5e-05 24.7 2.3 0.48 11.0 0.0 4.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCD23995.1 - 4.6e-05 23.6 9.9 0.069 13.5 0.1 5.3 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 CCD23995.1 - 8.7e-05 21.9 0.0 0.018 14.3 0.0 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.9 CCD23995.1 - 0.00088 19.0 1.3 0.0055 16.4 1.1 2.5 2 0 0 2 2 2 1 26S proteasome subunit RPN7 DUF4784 PF16023.5 CCD23995.1 - 0.0075 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4784) BTAD PF03704.17 CCD23995.1 - 0.013 16.0 0.0 0.054 13.9 0.0 1.9 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 CCD23995.1 - 0.054 14.2 11.3 75 4.3 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_10 PF13374.6 CCD23995.1 - 0.097 12.6 0.1 4.4 7.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC_tran PF00005.27 CCD23995.1 - 0.13 12.7 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF1765 PF08578.10 CCD23995.1 - 0.15 12.5 4.8 0.37 11.2 1.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1765) THP2 PF09432.10 CCD23996.1 - 1.2e-56 190.2 3.5 1.2e-56 190.2 3.5 2.1 2 0 0 2 2 2 1 Tho complex subunit THP2 IL5 PF02025.15 CCD23996.1 - 0.0042 17.4 1.3 0.012 15.9 0.3 2.2 2 0 0 2 2 2 1 Interleukin 5 NAD_binding_5 PF07994.12 CCD23996.1 - 0.16 11.3 2.8 0.37 10.1 0.9 2.2 2 1 0 2 2 2 0 Myo-inositol-1-phosphate synthase YecM PF06185.12 CCD23996.1 - 0.31 10.7 3.7 0.25 11.0 0.6 2.2 1 1 1 2 2 2 0 YecM protein DUF3979 PF13141.6 CCD23996.1 - 0.32 11.3 5.6 0.26 11.6 0.8 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3979) CpxA_peri PF16527.5 CCD23996.1 - 2.7 8.4 9.3 4.9 7.5 2.0 3.0 2 2 1 3 3 3 0 Two-component sensor protein CpxA, periplasmic domain GTP1_OBG PF01018.22 CCD23997.1 - 3.5e-37 127.4 1.4 5.7e-27 94.2 1.5 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 CCD23997.1 - 1.1e-19 70.5 0.0 2e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCD23997.1 - 4.8e-07 29.4 0.0 1.3e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 CCD23997.1 - 0.00018 21.0 0.0 0.00043 19.8 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Imm35 PF15567.6 CCD23997.1 - 0.03 14.5 0.1 1.8 8.8 0.1 2.5 2 0 0 2 2 2 0 Immunity protein 35 NMD3 PF04981.13 CCD23998.1 - 7.8e-84 280.9 1.5 1.5e-83 280.0 1.5 1.4 1 0 0 1 1 1 1 NMD3 family NinF PF05810.12 CCD23998.1 - 0.0067 16.3 1.5 0.0067 16.3 1.5 3.1 4 0 0 4 4 4 1 NinF protein DZR PF12773.7 CCD23998.1 - 0.025 14.6 4.7 4.3 7.4 5.0 2.7 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 CCD23998.1 - 0.31 11.1 7.3 9.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA VPS11_C PF12451.8 CCD23998.1 - 0.32 11.3 1.4 0.85 9.9 1.4 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal ATG7_N PF16420.5 CCD23999.1 - 9.4e-53 179.8 3.8 1.4e-52 179.2 3.8 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 CCD23999.1 - 2.1e-49 168.1 0.0 4e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CCD23999.1 - 0.0012 18.9 0.0 0.0083 16.2 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CCD23999.1 - 0.036 13.4 0.0 2.2 7.6 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CCD23999.1 - 0.071 12.8 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 CCD23999.1 - 0.19 12.0 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Proteasome PF00227.26 CCD24000.1 - 5.7e-54 182.5 0.1 7.6e-54 182.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCD24000.1 - 2.6e-12 46.1 0.0 5.4e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 CCD24001.1 - 2.3e-37 129.3 2.7 2.3e-37 129.3 2.7 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CCD24001.1 - 9.2e-18 64.7 7.7 9.2e-18 64.7 7.7 2.0 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal NPR1_like_C PF12313.8 CCD24001.1 - 0.036 13.6 0.1 0.39 10.2 0.1 2.2 2 0 0 2 2 2 0 NPR1/NIM1 like defence protein C terminal Enolase_C PF00113.22 CCD24002.1 - 5.6e-150 498.5 0.0 8.1e-150 498.0 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CCD24002.1 - 2e-56 189.8 0.4 3.2e-56 189.1 0.4 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CCD24002.1 - 4.1e-06 26.5 0.0 1.1e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CCD24002.1 - 0.12 11.6 0.4 0.52 9.4 0.1 2.0 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Ctr PF04145.15 CCD24003.1 - 2.5e-22 80.1 20.8 4.6e-21 76.0 16.5 2.4 2 1 0 2 2 2 1 Ctr copper transporter family UPF0242 PF06785.11 CCD24003.1 - 2.5 8.1 7.0 0.47 10.5 0.7 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FMO-like PF00743.19 CCD24004.1 - 9.3e-46 156.3 0.1 4.5e-37 127.7 0.1 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CCD24004.1 - 4.3e-20 72.2 0.3 1.8e-18 66.8 0.3 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CCD24004.1 - 1.9e-17 63.7 0.0 9e-16 58.2 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CCD24004.1 - 8e-16 58.1 0.0 1.1e-14 54.3 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CCD24004.1 - 1.1e-11 44.6 1.5 7.1e-10 38.5 0.1 3.3 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CCD24004.1 - 2.9e-07 30.4 0.0 0.00016 21.4 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCD24004.1 - 3.5e-06 27.2 0.0 1.2e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CCD24004.1 - 6.6e-06 25.1 0.1 0.0042 15.9 0.0 2.4 3 0 0 3 3 3 2 HI0933-like protein Amino_oxidase PF01593.24 CCD24004.1 - 0.0002 20.8 0.0 0.0039 16.5 0.1 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 CCD24004.1 - 0.002 17.4 0.0 0.018 14.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DUF5083 PF16890.5 CCD24004.1 - 0.046 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) Glu_dehyd_C PF16912.5 CCD24004.1 - 0.055 12.9 0.0 12 5.4 0.0 2.5 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus Adaptin_N PF01602.20 CCD24004.1 - 0.07 11.7 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Adaptin N terminal region Mqo PF06039.15 CCD24004.1 - 0.095 11.2 0.1 0.22 10.0 0.1 1.5 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 CCD24004.1 - 0.14 11.4 0.1 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 CCD24004.1 - 0.15 11.1 0.1 0.15 11.1 0.1 2.3 2 1 0 3 3 3 0 Glucose inhibited division protein A Fungal_trans PF04082.18 CCD24005.1 - 2.8e-24 85.6 0.9 2.8e-24 85.6 0.9 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD24005.1 - 4e-08 33.2 11.4 6.6e-08 32.5 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ParB PF08775.10 CCD24005.1 - 0.66 10.5 3.2 47 4.5 2.6 3.2 3 0 0 3 3 3 0 ParB family Oxidored_FMN PF00724.20 CCD24006.1 - 6e-137 456.5 0.0 6.9e-137 456.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Erv26 PF04148.13 CCD24007.1 - 1.7e-83 279.5 4.3 2e-83 279.3 4.3 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF996 PF06195.13 CCD24007.1 - 0.0013 19.0 1.9 0.0013 19.0 1.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF996) Cyt_bd_oxida_II PF02322.15 CCD24007.1 - 0.048 13.0 2.9 0.074 12.4 2.9 1.4 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Cytochrom_C_asm PF01578.20 CCD24007.1 - 0.72 9.6 5.0 0.49 10.1 1.3 2.3 2 1 1 3 3 3 0 Cytochrome C assembly protein RhoGAP PF00620.27 CCD24008.1 - 5.1e-05 23.1 0.0 0.00015 21.6 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain UBA_3 PF09288.10 CCD24008.1 - 0.033 14.0 1.5 0.19 11.6 0.0 2.6 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Seryl_tRNA_N PF02403.22 CCD24008.1 - 0.073 13.3 4.9 0.46 10.7 4.9 2.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4116 PF13475.6 CCD24008.1 - 0.21 11.3 3.1 3.3 7.5 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) 6PGD PF00393.19 CCD24009.1 - 3.1e-125 417.4 0.0 3.9e-125 417.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CCD24009.1 - 4.8e-51 173.1 0.0 6.9e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CCD24009.1 - 0.011 16.3 0.2 0.022 15.3 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 CCD24009.1 - 0.074 13.3 0.0 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 CCD24009.1 - 0.15 11.5 0.0 0.33 10.3 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3484 PF11983.8 CCD24010.1 - 0.052 14.7 1.0 0.21 12.7 0.1 2.6 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch DUF3110 PF11360.8 CCD24011.1 - 0.15 12.3 0.3 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3110) Prion PF00377.18 CCD24011.1 - 0.34 10.8 2.8 0.84 9.5 2.8 1.6 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain Retrotrans_gag PF03732.17 CCD24012.1 - 5.5e-05 23.4 0.1 9.1e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein P53_TAD PF08563.11 CCD24012.1 - 0.1 12.1 1.3 0.19 11.3 1.3 1.4 1 0 0 1 1 1 0 P53 transactivation motif RVT_1 PF00078.27 CCD24013.1 - 5.1e-31 107.9 0.1 9.2e-31 107.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CCD24013.1 - 2.2e-28 98.2 0.0 6e-28 96.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCD24013.1 - 4.6e-28 97.6 0.0 1e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CCD24013.1 - 1.7e-17 63.3 2.4 1.7e-17 63.3 2.4 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Peptidase_A2B PF12384.8 CCD24013.1 - 2.2e-17 63.1 0.1 5e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Ty3 transposon peptidase rve PF00665.26 CCD24013.1 - 1.3e-14 54.4 0.1 3.6e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 CCD24013.1 - 3.9e-05 24.2 0.0 7.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 CCD24013.1 - 0.00022 21.4 1.1 0.0014 18.8 0.1 2.8 2 0 0 2 2 2 1 H2C2 zinc finger RVP_2 PF08284.11 CCD24013.1 - 0.015 15.0 0.1 0.031 14.0 0.1 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CCD24013.1 - 0.018 15.6 0.0 0.038 14.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Raptor_N PF14538.6 CCD24014.1 - 1.6e-66 222.8 0.0 1.6e-66 222.8 0.0 2.7 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 CCD24014.1 - 4.1e-06 26.6 0.0 0.086 13.2 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat WD40 PF00400.32 CCD24014.1 - 5e-05 24.0 5.2 0.33 11.9 0.0 6.1 5 1 1 6 6 6 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 CCD24014.1 - 0.00024 21.1 0.2 0.6 10.2 0.0 3.3 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region AIP3 PF03915.13 CCD24014.1 - 1 8.4 23.2 0.015 14.4 12.9 2.4 2 0 0 2 2 2 0 Actin interacting protein 3 Exonuc_VII_L PF02601.15 CCD24014.1 - 8.4 5.9 20.6 0.12 11.9 9.8 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Cob_adeno_trans PF01923.18 CCD24014.1 - 8.6 6.5 6.9 30 4.7 6.9 1.9 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Elong_Iki1 PF10483.9 CCD24015.1 - 3.4e-78 263.2 0.2 3.9e-78 263.0 0.2 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Gpi16 PF04113.14 CCD24016.1 - 8.1e-186 618.8 0.0 1e-185 618.4 0.0 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component HEAT_EZ PF13513.6 CCD24017.1 - 2.4e-10 40.7 0.3 2.1 8.9 0.0 7.5 8 0 0 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 CCD24017.1 - 2.9e-09 37.2 0.0 0.17 12.3 0.0 7.4 7 1 2 9 9 9 2 HEAT repeats DUF3385 PF11865.8 CCD24017.1 - 6e-09 36.0 8.5 0.034 14.0 0.0 5.6 5 1 0 5 5 5 3 Domain of unknown function (DUF3385) MMS19_C PF12460.8 CCD24017.1 - 5e-07 29.2 0.6 1.1 8.2 0.0 4.7 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal HEAT PF02985.22 CCD24017.1 - 1.2e-06 28.3 8.1 3.4 8.2 0.0 8.7 12 0 0 12 12 9 2 HEAT repeat Vac14_Fab1_bd PF12755.7 CCD24017.1 - 1.2e-06 29.0 0.3 0.058 14.0 0.1 5.1 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 CCD24017.1 - 0.0018 17.9 0.6 0.97 9.0 0.0 4.6 3 2 3 6 6 6 1 NUC173 domain CLASP_N PF12348.8 CCD24017.1 - 0.013 15.1 3.8 1.8 8.1 0.0 3.8 4 0 0 4 4 4 0 CLASP N terminal ParcG PF10274.9 CCD24017.1 - 0.023 14.9 8.4 1.1 9.4 0.0 5.7 4 1 2 7 7 7 0 Parkin co-regulated protein Cnd1 PF12717.7 CCD24017.1 - 0.032 14.3 11.5 2.7 8.0 0.5 5.5 6 2 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Autophagy_C PF10381.9 CCD24017.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal Aminotran_4 PF01063.19 CCD24018.1 - 2.7e-21 76.5 0.5 7.3e-21 75.1 0.5 1.6 1 1 0 1 1 1 1 Amino-transferase class IV Symplekin_C PF12295.8 CCD24018.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal tRNA-synt_1g PF09334.11 CCD24019.1 - 1.9e-157 524.1 0.2 2.7e-157 523.5 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.10 CCD24019.1 - 3.5e-30 105.0 3.3 3.5e-30 105.0 3.3 2.0 2 0 0 2 2 2 1 MetRS-N binding domain tRNA-synt_1 PF00133.22 CCD24019.1 - 4.4e-11 41.7 1.5 0.00015 20.2 0.0 2.8 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CCD24019.1 - 0.0091 15.4 0.0 0.034 13.5 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 CCD24019.1 - 0.013 15.5 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Sigma54_CBD PF04963.13 CCD24019.1 - 0.035 14.0 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain DEAD PF00270.29 CCD24020.1 - 7.1e-48 162.7 0.5 2.1e-47 161.1 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD24020.1 - 1.2e-23 83.5 0.0 2.9e-22 79.1 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CCD24020.1 - 9.4e-19 67.4 0.6 1.8e-18 66.5 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CCD24020.1 - 4.2e-06 26.9 0.0 9e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 CCD24020.1 - 0.0032 16.8 0.0 0.0081 15.5 0.0 1.6 1 1 0 1 1 1 1 SecA DEAD-like domain AAA_22 PF13401.6 CCD24020.1 - 0.083 13.2 1.7 0.19 12.0 0.1 2.4 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 CCD24020.1 - 0.092 12.5 0.0 0.6 9.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 CCD24021.1 - 2.6e-49 168.0 2.4 1.7e-41 142.4 0.1 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24021.1 - 1.7e-22 80.0 0.3 6.2e-20 71.6 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCD24021.1 - 3.4e-05 22.8 0.2 3.4e-05 22.8 0.2 2.4 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CCD24021.1 - 0.0019 17.6 0.0 0.23 10.7 0.0 2.4 2 0 0 2 2 2 2 Kinase-like NOA36 PF06524.12 CCD24021.1 - 0.97 8.7 10.0 1.9 7.7 10.0 1.4 1 0 0 1 1 1 0 NOA36 protein Got1 PF04178.12 CCD24022.1 - 4.9e-14 52.7 12.9 9.6e-14 51.8 12.5 1.6 1 1 1 2 2 2 1 Got1/Sft2-like family DUF3784 PF12650.7 CCD24022.1 - 0.059 13.6 7.8 0.09 13.0 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) PEMT PF04191.13 CCD24022.1 - 0.39 11.1 6.1 0.47 10.9 0.5 2.7 1 1 1 2 2 2 0 Phospholipid methyltransferase Phage_holin_3_6 PF07332.11 CCD24022.1 - 2 8.5 6.8 0.25 11.4 1.7 1.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Amidase PF01425.21 CCD24023.1 - 4.9e-108 362.0 0.0 5.7e-108 361.8 0.0 1.0 1 0 0 1 1 1 1 Amidase Dynamitin PF04912.14 CCD24024.1 - 1.7e-19 70.4 24.6 2.2e-19 70.1 24.6 1.2 1 0 0 1 1 1 1 Dynamitin TRAF_BIRC3_bd PF16673.5 CCD24024.1 - 0.21 11.4 7.3 0.92 9.4 0.9 3.2 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Feld-I_B PF09252.10 CCD24024.1 - 0.27 11.2 2.3 2.3 8.3 0.3 2.7 2 0 0 2 2 2 0 Allergen Fel d I-B chain YueH PF14166.6 CCD24024.1 - 0.33 10.9 0.1 0.33 10.9 0.1 4.8 4 1 1 5 5 5 0 YueH-like protein GvpL_GvpF PF06386.11 CCD24024.1 - 0.4 10.6 2.6 0.23 11.4 0.7 1.6 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF MCC-bdg_PDZ PF10506.9 CCD24024.1 - 0.46 10.5 3.3 16 5.6 0.3 3.7 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DASH_Dam1 PF08653.10 CCD24024.1 - 7 6.5 7.8 3 7.7 0.2 4.2 4 1 0 4 4 4 0 DASH complex subunit Dam1 DUF4140 PF13600.6 CCD24024.1 - 8.9 6.8 7.3 14 6.2 0.2 3.4 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF2406 PF10295.9 CCD24025.1 - 2.2e-28 98.7 0.3 6e-28 97.3 0.3 1.8 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Aminotran_1_2 PF00155.21 CCD24026.1 - 5e-65 220.0 0.1 6.1e-65 219.7 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_S10 PF00450.22 CCD24027.1 - 5e-127 424.8 0.2 6e-127 424.5 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 CCD24027.1 - 3.1e-15 56.8 1.8 7e-14 52.4 1.8 2.4 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide UBA_2 PF08587.11 CCD24027.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) V_cholerae_RfbT PF05575.11 CCD24027.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein DUF3591 PF12157.8 CCD24029.1 - 9.3e-166 551.9 0.2 9.3e-166 551.9 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 CCD24029.1 - 3.9e-05 23.4 0.4 8.6e-05 22.3 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CCD24029.1 - 0.11 12.7 1.7 0.11 12.7 0.4 1.7 2 0 0 2 2 2 0 Zinc knuckle DNA_pol_phi PF04931.13 CCD24029.1 - 2.4 6.2 21.4 4.1 5.4 21.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi Cyclin_N PF00134.23 CCD24030.1 - 3.4e-09 36.5 1.9 5.5e-09 35.8 0.3 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain PPTA PF01239.22 CCD24031.1 - 2e-38 129.0 16.1 4.4e-10 39.0 1.0 6.0 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat VPS53_C PF16854.5 CCD24032.1 - 1e-82 277.0 8.4 1e-82 277.0 8.4 2.6 3 0 0 3 3 3 1 Vacuolar protein sorting-associated protein 53 C-terminus Vps53_N PF04100.12 CCD24032.1 - 1.2e-79 268.0 15.7 1.2e-79 268.0 15.7 2.2 2 1 0 2 2 2 1 Vps53-like, N-terminal BORCS7 PF16088.5 CCD24032.1 - 0.026 14.8 8.6 0.056 13.7 1.7 3.9 3 1 1 4 4 4 0 BLOC-1-related complex sub-unit 7 CHASE6_C PF17150.4 CCD24032.1 - 0.05 14.3 0.1 0.21 12.3 0.1 2.1 1 0 0 1 1 1 0 C-terminal domain of two-partite extracellular sensor domain Filo_VP35 PF02097.15 CCD24032.1 - 0.13 11.3 0.6 0.29 10.1 0.6 1.5 1 0 0 1 1 1 0 Filoviridae VP35 DivIVA PF05103.13 CCD24032.1 - 0.26 11.4 1.8 3 7.9 0.0 3.3 5 0 0 5 5 5 0 DivIVA protein Cpn60_TCP1 PF00118.24 CCD24033.1 - 9e-152 506.1 8.9 1e-151 505.9 8.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 CCD24033.1 - 0.038 14.3 0.1 0.33 11.3 0.0 2.4 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor EAL PF00563.20 CCD24033.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 EAL domain PUF PF00806.19 CCD24034.1 - 2.9e-32 108.5 11.1 7.5e-05 22.2 0.1 9.2 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat FANCI_S1-cap PF14674.6 CCD24034.1 - 0.035 14.2 0.2 0.12 12.5 0.2 2.0 1 0 0 1 1 1 0 FANCI solenoid 1 cap HMA PF00403.26 CCD24034.1 - 0.066 13.7 0.0 5.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Heavy-metal-associated domain DUF3294 PF07957.11 CCD24035.1 - 6.5e-86 287.5 7.6 7.2e-86 287.3 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) Tricorn_C1 PF14684.6 CCD24035.1 - 0.066 13.3 1.7 7 6.8 0.0 3.1 3 0 0 3 3 3 0 Tricorn protease C1 domain ArlS_N PF18719.1 CCD24035.1 - 0.069 13.4 7.0 0.14 12.3 0.4 2.3 2 0 0 2 2 2 0 ArlS sensor domain Mu-like_Pro PF10123.9 CCD24035.1 - 0.087 12.4 2.1 0.67 9.4 0.3 2.0 2 0 0 2 2 2 0 Mu-like prophage I protein DUF4277 PF14104.6 CCD24035.1 - 0.13 12.7 1.1 0.3 11.5 1.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4277) SbcD_C PF12320.8 CCD24035.1 - 0.19 12.1 5.2 0.049 13.9 0.8 2.2 2 2 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain PCRF PF03462.18 CCD24035.1 - 0.88 9.4 5.5 2.2 8.1 0.7 2.1 2 0 0 2 2 2 0 PCRF domain DUF16 PF01519.16 CCD24035.1 - 3.6 8.1 15.5 0.36 11.3 5.0 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 UPF0242 PF06785.11 CCD24035.1 - 7.5 6.6 12.9 0.86 9.7 2.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LTV PF04180.14 CCD24036.1 - 3.7e-113 379.1 37.8 4.7e-113 378.8 37.8 1.1 1 0 0 1 1 1 1 Low temperature viability protein RNA_pol_Rbc25 PF08292.12 CCD24037.1 - 1.2e-49 167.8 3.2 3.4e-49 166.4 3.2 1.6 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CCD24037.1 - 1e-18 67.5 0.0 1.5e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CCD24037.1 - 0.0012 19.1 0.8 0.0095 16.3 0.0 2.5 2 1 0 2 2 2 1 S1 RNA binding domain AAA PF00004.29 CCD24038.1 - 1.3e-40 138.9 0.0 2.2e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCD24038.1 - 2.6e-06 27.1 0.0 7.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CCD24038.1 - 4e-05 23.6 0.0 0.00014 21.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCD24038.1 - 4.7e-05 23.7 0.0 0.0022 18.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 CCD24038.1 - 8.8e-05 22.7 0.0 0.00026 21.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CCD24038.1 - 0.00017 22.1 0.1 0.0031 17.9 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 CCD24038.1 - 0.00073 18.8 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CCD24038.1 - 0.0022 17.8 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CCD24038.1 - 0.011 16.0 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CCD24038.1 - 0.018 15.6 0.1 0.059 13.9 0.0 2.0 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 CCD24038.1 - 0.019 14.7 0.1 0.069 12.9 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CCD24038.1 - 0.024 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CCD24038.1 - 0.025 14.1 0.0 0.064 12.8 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CCD24038.1 - 0.026 14.9 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 CCD24038.1 - 0.038 13.9 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CCD24038.1 - 0.045 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CCD24038.1 - 0.05 12.8 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 CCD24038.1 - 0.062 13.2 0.1 4.6 7.1 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CCD24038.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CCD24038.1 - 0.093 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 CCD24038.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 CCD24038.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Aa_trans PF01490.18 CCD24039.1 - 1.3e-97 327.1 34.5 1.6e-97 326.8 34.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CENP-B_dimeris PF09026.10 CCD24039.1 - 0.8 10.1 4.5 1.9 8.9 4.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pro_dh PF01619.18 CCD24040.1 - 5.5e-56 190.3 0.0 8e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase FAD_binding_2 PF00890.24 CCD24041.1 - 6.9e-123 410.8 2.7 8.5e-123 410.5 2.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CCD24041.1 - 1.4e-45 154.4 0.2 2.1e-45 153.8 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 CCD24041.1 - 1.3e-05 24.5 2.7 0.0042 16.2 2.2 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 CCD24041.1 - 3.5e-05 23.2 0.1 0.0035 16.6 0.0 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 CCD24041.1 - 6.4e-05 22.3 0.6 0.00016 21.0 0.1 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CCD24041.1 - 0.0027 17.0 0.4 0.0065 15.8 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 CCD24041.1 - 0.004 16.8 2.2 0.014 15.0 2.2 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CCD24041.1 - 0.055 12.2 1.0 0.19 10.4 0.1 2.3 3 0 0 3 3 3 0 HI0933-like protein Metallophos PF00149.28 CCD24042.1 - 1.6e-10 41.9 1.4 1.6e-10 41.9 1.4 1.9 2 1 1 3 3 3 1 Calcineurin-like phosphoesterase DBR1 PF05011.13 CCD24042.1 - 2.9e-08 34.2 1.3 5.2e-08 33.4 0.1 2.0 1 1 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Ta0938 PF11494.8 CCD24042.1 - 0.034 14.4 0.1 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 Ta0938 NAD_binding_1 PF00175.21 CCD24043.1 - 2.9e-24 85.8 0.0 4.3e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CCD24043.1 - 9.2e-21 74.1 0.0 1.6e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CCD24043.1 - 1.7e-06 28.3 0.0 0.00019 21.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 CCD24044.1 - 8.2e-25 87.0 0.0 1.3e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CCD24044.1 - 5.4e-19 68.9 0.0 8e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CCD24044.1 - 7.5e-05 22.9 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Carb_kinase PF01256.17 CCD24045.1 - 1.3e-71 240.9 0.0 7.4e-71 238.5 0.0 1.8 1 1 1 2 2 2 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 CCD24045.1 - 4.2e-06 26.3 0.0 7.7e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.15 CCD24045.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Lantibiotic_a PF14867.6 CCD24045.1 - 6.7 6.5 6.3 0.7 9.7 1.0 2.0 2 0 0 2 2 2 0 Lantibiotic alpha His_Phos_1 PF00300.22 CCD24046.1 - 2.4e-39 135.1 0.1 3.1e-31 108.6 0.1 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Tnp_22_dsRBD PF17490.2 CCD24046.1 - 0.065 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 L1 transposable element dsRBD-like domain SRPRB PF09439.10 CCD24047.1 - 2.9e-53 180.0 1.1 3.6e-53 179.7 1.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CCD24047.1 - 3e-09 36.6 0.0 4.1e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCD24047.1 - 3.1e-06 27.3 0.1 6e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCD24047.1 - 0.0004 19.9 0.1 0.00096 18.7 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B ATPase_2 PF01637.18 CCD24047.1 - 0.002 18.1 0.4 0.042 13.8 0.0 2.2 1 1 0 2 2 2 1 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 CCD24047.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 CCD24047.1 - 0.012 15.4 0.1 0.016 15.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CCD24047.1 - 0.012 15.9 0.1 0.088 13.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 CCD24047.1 - 0.015 15.1 0.3 0.2 11.4 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Vps4_C PF09336.10 CCD24047.1 - 0.017 15.1 0.3 31 4.6 0.0 3.5 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain AAA_21 PF13304.6 CCD24047.1 - 0.023 14.5 1.3 0.048 13.5 0.4 2.0 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF5099 PF17025.5 CCD24047.1 - 0.063 13.7 0.8 0.36 11.3 0.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5099) AAA_23 PF13476.6 CCD24047.1 - 0.066 13.7 3.4 0.096 13.2 0.6 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CCD24047.1 - 0.13 12.2 0.9 1.8 8.4 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF3149 PF11346.8 CCD24047.1 - 0.41 10.3 1.5 0.73 9.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Rsm22 PF09243.10 CCD24048.1 - 5.6e-30 104.5 0.2 1.7e-09 37.3 0.0 4.3 3 1 1 4 4 4 4 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 CCD24048.1 - 0.00017 21.5 0.0 0.00048 20.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ribosomal_S27e PF01667.17 CCD24049.1 - 3.1e-30 103.7 2.8 4e-30 103.3 2.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.21 CCD24049.1 - 0.0076 16.4 0.8 0.0093 16.2 0.8 1.2 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain TF_Zn_Ribbon PF08271.12 CCD24049.1 - 0.024 14.2 4.2 0.035 13.6 4.2 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zf-ACC PF17848.1 CCD24049.1 - 3.2 7.9 6.4 19 5.4 0.2 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Pkinase PF00069.25 CCD24050.1 - 7.5e-65 218.9 0.0 9.4e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24050.1 - 1.3e-35 122.9 0.0 1.8e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCD24050.1 - 0.024 13.6 0.4 0.067 12.1 0.1 1.9 3 0 0 3 3 3 0 Haspin like kinase domain Calcipressin PF04847.12 CCD24051.1 - 8.6e-16 58.2 1.5 2.3e-15 56.8 1.5 1.8 1 1 0 1 1 1 1 Calcipressin Peptidase_M1 PF01433.20 CCD24052.1 - 1.9e-87 292.4 5.0 1.9e-87 292.4 5.0 1.7 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 CCD24052.1 - 6.9e-81 272.2 0.8 1.3e-78 264.7 0.4 2.3 2 0 0 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CCD24052.1 - 5.5e-51 173.4 0.8 1.1e-50 172.4 0.8 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain adh_short PF00106.25 CCD24053.1 - 7.6e-11 41.8 0.0 3e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CCD24053.1 - 1.2e-06 28.3 0.0 1.2e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.19 CCD24053.1 - 0.00067 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.10 CCD24053.1 - 0.0011 18.9 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CCD24053.1 - 0.0021 17.6 0.1 0.0036 16.8 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_1 PF00667.20 CCD24054.1 - 1.1e-72 244.3 0.0 1.9e-72 243.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CCD24054.1 - 2.8e-29 102.1 0.2 4.8e-29 101.4 0.2 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CCD24054.1 - 1.4e-21 77.2 0.0 3.7e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain MAGE PF01454.19 CCD24055.1 - 1.1e-45 156.0 0.1 1.4e-45 155.6 0.1 1.1 1 0 0 1 1 1 1 MAGE family YtzH PF14165.6 CCD24055.1 - 0.03 14.7 2.8 1.7 9.1 0.0 2.9 2 1 1 3 3 3 0 YtzH-like protein DUF3463 PF11946.8 CCD24055.1 - 0.17 11.7 0.4 5.1 6.9 0.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3463) Inositol_P PF00459.25 CCD24056.1 - 6.2e-71 239.1 0.0 7e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Gamma-thionin PF00304.20 CCD24056.1 - 0.29 11.4 3.4 0.64 10.3 3.4 1.6 1 1 0 1 1 1 0 Gamma-thionin family DUF836 PF05768.14 CCD24057.1 - 4.9e-17 62.1 2.3 6.4e-17 61.7 2.3 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 CCD24057.1 - 0.00016 21.8 0.1 0.00039 20.6 0.1 1.7 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 CCD24057.1 - 0.064 13.7 0.3 0.082 13.4 0.3 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DUF724 PF05266.14 CCD24058.1 - 0.011 15.5 11.4 0.011 15.5 11.4 6.7 2 2 6 8 8 8 0 Protein of unknown function (DUF724) ATG16 PF08614.11 CCD24058.1 - 3.9 7.6 94.5 0.55 10.4 26.4 5.6 3 3 3 6 6 6 0 Autophagy protein 16 (ATG16) PAP2 PF01569.21 CCD24059.1 - 2e-22 79.4 0.3 2e-22 79.4 0.3 2.3 1 1 1 2 2 2 1 PAP2 superfamily MerC PF03203.14 CCD24059.1 - 0.00022 21.6 0.7 0.0056 17.1 0.2 2.3 2 0 0 2 2 2 1 MerC mercury resistance protein SLATT_1 PF18181.1 CCD24059.1 - 0.023 14.6 0.2 8.9 6.3 0.0 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Colicin_V PF02674.16 CCD24059.1 - 0.074 13.0 7.8 2.9 7.8 0.1 3.3 2 1 1 3 3 3 0 Colicin V production protein RseC_MucC PF04246.12 CCD24059.1 - 0.97 9.4 4.4 2.2 8.2 2.7 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Choline_transpo PF04515.12 CCD24059.1 - 1.1 8.4 9.4 0.15 11.2 4.8 1.8 2 1 0 2 2 2 0 Plasma-membrane choline transporter CPBP PF02517.16 CCD24059.1 - 5.2 7.5 11.1 0.61 10.5 5.0 2.2 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease DUF4131 PF13567.6 CCD24059.1 - 5.4 6.6 7.9 85 2.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) HGTP_anticodon2 PF12745.7 CCD24060.1 - 1.9e-89 299.7 4.7 1.9e-89 299.7 4.7 2.8 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 CCD24060.1 - 1.2e-67 228.1 7.7 8.9e-43 146.5 0.1 4.6 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24060.1 - 3.6e-36 124.8 0.1 5e-20 71.9 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 CCD24060.1 - 1.3e-18 67.3 2.9 3.6e-18 65.9 1.4 2.7 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 CCD24060.1 - 1.1e-12 47.8 0.0 2.2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase APH PF01636.23 CCD24060.1 - 0.0093 15.9 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 CCD24060.1 - 0.057 13.0 6.9 1.4 8.5 0.0 3.8 4 0 0 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 Ribosomal_L6e PF01159.19 CCD24060.1 - 0.51 10.9 4.7 9.8 6.8 5.6 2.7 2 0 0 2 2 2 0 Ribosomal protein L6e HGTP_anticodon PF03129.20 CCD24060.1 - 0.78 9.9 4.4 1 9.6 0.0 3.2 3 0 0 3 3 3 0 Anticodon binding domain CTD_bind PF04818.13 CCD24061.1 - 8.2e-18 65.0 2.4 1e-17 64.7 0.2 2.4 2 1 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.8 CCD24061.1 - 0.0013 18.7 0.7 0.0013 18.7 0.7 2.0 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 DEAD PF00270.29 CCD24062.1 - 4.8e-26 91.6 0.0 1.2e-25 90.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 CCD24062.1 - 1.7e-20 73.6 0.2 4.5e-20 72.2 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 CCD24062.1 - 1.7e-14 54.1 0.1 5e-13 49.4 0.1 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD24062.1 - 5.3e-08 33.0 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 CCD24062.1 - 0.00048 20.5 0.1 0.0011 19.2 0.1 1.7 1 0 0 1 1 1 1 DNA replication factor CDT1 like SRX PF09201.10 CCD24063.1 - 1.2e-61 206.8 2.2 2.8e-61 205.7 2.2 1.7 1 0 0 1 1 1 1 SRX, signal recognition particle receptor alpha subunit SRP54 PF00448.22 CCD24063.1 - 1.2e-47 162.1 0.1 1.3e-28 99.9 0.1 2.4 1 1 1 2 2 2 2 SRP54-type protein, GTPase domain SRP54_N PF02881.19 CCD24063.1 - 1.5e-07 31.6 0.4 5.1e-07 29.8 0.4 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain SRP-alpha_N PF04086.13 CCD24063.1 - 1.5e-05 25.1 0.5 5.7e-05 23.2 0.1 2.0 2 1 1 3 3 3 1 Signal recognition particle, alpha subunit, N-terminal AAA_31 PF13614.6 CCD24063.1 - 0.00058 19.8 0.2 0.0073 16.2 0.2 2.6 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 CCD24063.1 - 0.00061 18.9 0.0 0.0014 17.6 0.0 1.7 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 CCD24063.1 - 0.00099 19.2 0.2 0.0055 16.7 0.0 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 CCD24063.1 - 0.0012 18.4 0.0 0.003 17.2 0.0 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArsA_ATPase PF02374.15 CCD24063.1 - 0.0018 17.5 0.0 0.17 11.0 0.0 2.6 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 CCD24063.1 - 0.0073 15.8 0.0 0.02 14.3 0.0 1.8 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_30 PF13604.6 CCD24063.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CCD24063.1 - 0.043 13.5 0.0 0.14 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Csm1_B PF18211.1 CCD24063.1 - 0.054 13.3 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 Csm1 subunit domain B AAA_22 PF13401.6 CCD24063.1 - 0.096 13.0 0.0 0.33 11.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain DUF87 PF01935.17 CCD24063.1 - 1.6 8.8 8.3 1.3 9.0 0.3 3.5 4 0 0 4 4 4 0 Helicase HerA, central domain zf-HIT PF04438.16 CCD24064.1 - 6.2e-09 35.6 11.1 1.1e-08 34.7 11.1 1.5 1 0 0 1 1 1 1 HIT zinc finger FOP_dimer PF09398.10 CCD24064.1 - 0.024 14.9 0.2 0.084 13.1 0.2 2.0 1 0 0 1 1 1 0 FOP N terminal dimerisation domain Ku_C PF03730.14 CCD24064.1 - 0.25 12.1 0.2 0.25 12.1 0.2 2.1 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm RNB PF00773.19 CCD24065.1 - 3e-55 187.8 3.6 6.6e-55 186.7 3.6 1.6 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CCD24065.1 - 2.1e-23 82.1 0.0 6.8e-23 80.5 0.0 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 CCD24065.1 - 1.8e-22 79.5 0.7 1.3e-21 76.7 0.0 2.6 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 CCD24065.1 - 5.5e-07 29.7 0.0 0.00015 21.8 0.0 3.0 2 0 0 2 2 2 1 Cold shock domain Rrp44_CSD1 PF17216.3 CCD24065.1 - 0.00012 21.9 0.1 0.00042 20.1 0.1 1.9 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_RNB PF08206.11 CCD24065.1 - 0.0041 16.8 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain DUF489 PF04356.12 CCD24065.1 - 0.44 10.5 5.3 1.3 9.0 5.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Pyridoxal_deC PF00282.19 CCD24066.1 - 2.3e-17 62.8 0.0 4.6e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 CCD24066.1 - 7.4e-06 25.5 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CCD24066.1 - 0.00018 20.6 0.0 0.0028 16.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V HDA2-3 PF11496.8 CCD24067.1 - 9.7e-60 202.2 24.2 9.7e-60 202.2 24.2 3.3 2 2 1 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Mhr1 PF12829.7 CCD24068.1 - 4.1e-23 81.3 0.5 8.3e-23 80.3 0.5 1.5 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination OSCP PF00213.18 CCD24069.1 - 2.3e-40 138.5 2.6 2.8e-40 138.3 2.6 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit AATF-Che1 PF13339.6 CCD24070.1 - 5.4e-24 85.4 12.9 5.4e-24 85.4 12.9 4.4 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 CCD24070.1 - 4.5e-23 81.6 0.6 4.5e-23 81.6 0.6 4.5 4 1 0 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal RNase_H2-Ydr279 PF09468.10 CCD24071.1 - 6.2e-25 88.3 1.1 1.3e-24 87.2 1.1 1.6 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 CCD24071.1 - 2.6e-13 50.0 1.2 6.6e-13 48.7 1.2 1.7 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain AGOG PF09171.10 CCD24071.1 - 0.026 13.9 0.2 0.041 13.2 0.2 1.4 1 0 0 1 1 1 0 N-glycosylase/DNA lyase AA_kinase PF00696.28 CCD24072.1 - 1.1e-34 120.1 0.7 2e-34 119.2 0.7 1.4 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 CCD24072.1 - 1.5e-19 69.7 0.0 3.3e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 PUA domain CPSF_A PF03178.15 CCD24073.1 - 2.1e-86 290.2 0.0 1.1e-85 287.8 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region HPS3_N PF14761.6 CCD24073.1 - 0.059 12.9 0.5 10 5.6 0.1 3.1 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3 DUF1743 PF08489.11 CCD24074.1 - 0.038 14.0 0.2 0.085 12.9 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1743) PAZ PF02170.22 CCD24074.1 - 0.11 12.4 0.9 0.17 11.7 0.9 1.5 1 1 1 2 2 2 0 PAZ domain GHMP_kinases_N PF00288.26 CCD24075.1 - 1.8e-16 60.1 0.4 5.8e-16 58.5 0.2 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CCD24075.1 - 3.8e-07 30.4 0.0 8.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal PIG-F PF06699.11 CCD24076.1 - 5.3e-26 91.9 19.2 7.4e-25 88.1 19.2 2.0 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F TauE PF01925.19 CCD24076.1 - 0.12 11.9 9.4 0.97 9.0 9.2 2.2 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Zn_clus PF00172.18 CCD24077.1 - 5.2e-07 29.7 7.5 8.8e-07 28.9 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.21 CCD24078.1 - 8.2e-45 152.9 0.1 1.1e-44 152.5 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HIT PF01230.23 CCD24079.1 - 4.8e-25 88.2 0.0 8.9e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CCD24079.1 - 0.0013 19.2 0.0 0.0023 18.4 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding PMT PF02366.18 CCD24081.1 - 1.3e-16 60.9 20.6 1.3e-16 60.9 20.6 3.2 3 1 1 4 4 4 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 CCD24081.1 - 0.00015 21.7 0.0 0.00036 20.4 0.0 1.7 1 1 0 1 1 1 1 MIR domain Med21 PF11221.8 CCD24082.1 - 4.9e-43 146.8 2.6 4.9e-43 146.8 2.6 1.9 2 0 0 2 2 2 1 Subunit 21 of Mediator complex Med9 PF07544.13 CCD24082.1 - 0.0036 17.4 0.9 0.0036 17.4 0.9 2.1 2 1 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Pox_polyA_pol_C PF12629.7 CCD24082.1 - 0.0052 16.6 0.0 0.42 10.4 0.0 2.1 1 1 0 1 1 1 1 Poxvirus poly(A) polymerase C-terminal domain FYVE PF01363.21 CCD24083.1 - 1.2e-17 63.8 13.4 1.2e-17 63.8 13.4 2.9 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 CCD24083.1 - 2.6e-07 30.9 4.3 2.6e-07 30.9 4.3 4.2 3 1 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 CCD24083.1 - 0.00022 20.9 8.9 0.0011 18.6 8.9 2.3 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CCD24083.1 - 0.0037 17.3 3.9 0.0037 17.3 3.9 3.9 5 0 0 5 5 5 1 RING-type zinc-finger DUF3657 PF12394.8 CCD24083.1 - 0.0046 17.5 0.1 0.028 14.9 0.0 2.3 2 0 0 2 2 2 1 Protein FAM135 zf-C3HC4 PF00097.25 CCD24083.1 - 0.0057 16.5 4.6 0.0057 16.5 4.6 4.7 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Brix PF04427.18 CCD24084.1 - 3.3e-50 170.9 2.5 6e-50 170.0 2.5 1.4 1 0 0 1 1 1 1 Brix domain DUF4718 PF15842.5 CCD24084.1 - 0.018 14.9 4.2 0.036 13.9 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) DUF4692 PF15763.5 CCD24084.1 - 0.46 10.9 5.1 1.1 9.7 5.1 1.6 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DEAD PF00270.29 CCD24085.1 - 1.6e-48 164.8 0.0 2.8e-48 164.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD24085.1 - 9.1e-31 106.5 0.2 7.1e-30 103.6 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD24085.1 - 1.3e-06 28.5 3.3 3.5e-05 23.9 0.0 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CCD24085.1 - 0.024 15.0 0.0 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 CCD24085.1 - 0.025 13.8 0.0 0.025 13.8 0.0 2.2 2 0 0 2 2 1 0 ERCC3/RAD25/XPB C-terminal helicase DDHD PF02862.17 CCD24085.1 - 0.042 14.0 1.7 0.06 13.5 1.7 1.3 1 0 0 1 1 1 0 DDHD domain GLTP PF08718.11 CCD24085.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.8 4 0 0 4 4 3 0 Glycolipid transfer protein (GLTP) FAM176 PF14851.6 CCD24085.1 - 0.18 11.5 10.5 0.34 10.6 10.5 1.4 1 0 0 1 1 1 0 FAM176 family Tim54 PF11711.8 CCD24085.1 - 0.46 9.2 7.7 0.67 8.7 7.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DNA_pol_phi PF04931.13 CCD24085.1 - 1.2 7.2 13.4 1.7 6.7 13.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.14 CCD24085.1 - 2.1 8.1 15.2 3.8 7.2 15.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CPSF100_C PF13299.6 CCD24085.1 - 2.2 8.5 10.5 3.8 7.7 10.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4637 PF15470.6 CCD24085.1 - 3.5 7.3 10.7 5.9 6.6 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RP-C_C PF11800.8 CCD24085.1 - 4.5 7.3 9.3 7.5 6.6 9.3 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region TERB2 PF15101.6 CCD24085.1 - 5.3 7.1 8.6 10 6.1 8.6 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Zip PF02535.22 CCD24085.1 - 7.9 5.6 5.9 11 5.1 5.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter UBA_e1_thiolCys PF10585.9 CCD24085.1 - 8.8 6.2 12.7 15 5.4 12.7 1.2 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site DUF913 PF06025.12 CCD24085.1 - 8.8 5.2 8.1 15 4.4 8.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4471 PF14740.6 CCD24085.1 - 9.9 5.3 10.0 15 4.7 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Otopetrin PF03189.13 CCD24087.1 - 0.032 13.0 0.2 0.7 8.6 0.0 3.3 2 1 0 2 2 2 0 Otopetrin Ins_P5_2-kin PF06090.12 CCD24088.1 - 1.3e-21 77.4 1.1 3.2e-21 76.1 1.1 1.6 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF1244 PF06844.11 CCD24088.1 - 0.11 12.7 0.1 0.3 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) Methyltransf_23 PF13489.6 CCD24089.1 - 2.9e-19 69.5 0.0 4.7e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCD24089.1 - 4.1e-12 46.7 0.0 1.2e-11 45.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCD24089.1 - 2e-09 38.0 0.0 3.5e-07 30.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CCD24089.1 - 2.7e-09 36.7 1.0 0.00019 20.9 0.0 3.2 2 1 1 3 3 3 3 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 CCD24089.1 - 5e-07 30.3 0.0 0.046 14.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CCD24089.1 - 4.2e-06 26.6 0.0 1.1e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Cyclin PF08613.11 CCD24090.1 - 6.4e-07 29.9 2.2 9.1e-07 29.4 2.2 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CCD24090.1 - 1.1e-06 28.4 0.4 2.1e-06 27.5 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Scs3p PF10261.9 CCD24091.1 - 1.2e-21 77.3 12.6 8.4e-16 58.2 2.0 2.5 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 CCD24091.1 - 0.0009 19.0 1.0 0.0018 18.0 0.4 1.9 1 1 1 2 2 2 1 PAP2 superfamily DUF2776 PF10951.8 CCD24091.1 - 0.029 13.6 6.4 0.13 11.5 6.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2776) Ubiq-assoc PF09145.10 CCD24092.1 - 1.8e-25 88.7 2.4 3.7e-25 87.6 2.4 1.6 1 0 0 1 1 1 1 Ubiquitin-associated TPR_1 PF00515.28 CCD24092.1 - 5.8e-10 38.6 3.6 0.015 15.1 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCD24092.1 - 2.4e-08 33.4 1.4 0.1 12.8 0.2 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCD24092.1 - 0.0027 17.9 0.1 3.1 8.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 CCD24092.1 - 0.016 15.8 0.1 0.18 12.5 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Exonuc_VIII PF06630.11 CCD24092.1 - 0.041 13.7 0.2 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Enterobacterial exodeoxyribonuclease VIII MIT PF04212.18 CCD24092.1 - 0.15 12.2 3.5 3.6 7.7 0.3 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 CCD24092.1 - 0.91 9.9 6.8 10 6.6 0.6 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 CCD24092.1 - 2.7 7.8 5.0 2.1 8.1 0.1 3.0 4 0 0 4 4 4 0 TPR repeat DASH_Dad4 PF08650.10 CCD24093.1 - 9.4e-32 108.8 8.0 1e-31 108.7 8.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 NPV_P10 PF05531.12 CCD24093.1 - 0.0074 16.7 0.7 0.0086 16.5 0.7 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein UPF0122 PF04297.14 CCD24093.1 - 0.018 15.3 0.8 0.02 15.1 0.8 1.1 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HU-CCDC81_bac_2 PF18175.1 CCD24093.1 - 0.02 14.8 1.2 0.033 14.1 1.2 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 Nsp1_C PF05064.13 CCD24093.1 - 0.035 13.9 0.9 0.039 13.8 0.9 1.1 1 0 0 1 1 1 0 Nsp1-like C-terminal region DASH_Dad1 PF08649.10 CCD24093.1 - 0.053 13.7 5.6 0.096 12.9 5.6 1.5 1 1 0 1 1 1 0 DASH complex subunit Dad1 FAM117 PF15388.6 CCD24093.1 - 0.068 12.6 0.4 0.071 12.5 0.4 1.1 1 0 0 1 1 1 0 Protein Family FAM117 Asparaginase PF00710.20 CCD24094.1 - 7.6e-57 191.9 0.0 1.4e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CCD24094.1 - 2.2e-16 60.1 0.0 7.4e-16 58.4 0.0 1.8 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain HMG_box PF00505.19 CCD24095.1 - 2.7e-06 27.7 5.8 2.7e-05 24.5 0.1 3.3 3 0 0 3 3 3 1 HMG (high mobility group) box Cas_APE2256 PF09651.10 CCD24095.1 - 0.037 13.9 1.0 0.11 12.4 1.0 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) RP-C_C PF11800.8 CCD24095.1 - 1.1 9.3 7.3 1.1 9.3 5.9 1.7 2 0 0 2 2 2 0 Replication protein C C-terminal region FKS1_dom1 PF14288.6 CCD24095.1 - 5.9 7.3 8.6 0.23 11.8 0.3 2.6 2 1 1 3 3 3 0 1,3-beta-glucan synthase subunit FKS1, domain-1 PBP PF01161.20 CCD24096.1 - 0.00017 21.9 0.0 0.00032 21.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ATP-synt_E PF05680.12 CCD24097.1 - 5.2e-17 62.0 0.1 5.9e-17 61.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain FYVE PF01363.21 CCD24098.1 - 2.4e-19 69.2 23.8 7.6e-18 64.4 4.2 3.3 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 CCD24098.1 - 2.7e-14 52.6 3.7 2.9e-14 52.5 1.3 2.3 2 0 0 2 2 2 1 Rabenosyn Rab binding domain zf-C2H2_6 PF13912.6 CCD24098.1 - 0.0019 18.1 0.1 0.0019 18.1 0.1 4.1 5 0 0 5 5 5 1 C2H2-type zinc finger NPV_P10 PF05531.12 CCD24098.1 - 0.006 17.0 1.1 0.006 17.0 1.1 2.9 3 1 0 3 3 2 1 Nucleopolyhedrovirus P10 protein DZR PF12773.7 CCD24098.1 - 0.0066 16.5 4.3 0.0066 16.5 4.3 4.2 5 0 0 5 5 5 1 Double zinc ribbon zf-C2H2_4 PF13894.6 CCD24098.1 - 0.0078 17.0 0.2 0.0078 17.0 0.2 6.3 6 2 2 8 8 6 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CCD24098.1 - 0.015 15.8 0.3 0.015 15.8 0.3 5.0 3 2 1 4 4 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 CCD24098.1 - 0.03 14.6 0.4 0.03 14.6 0.4 3.2 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CCD24098.1 - 0.057 13.7 0.5 0.057 13.7 0.5 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding UBZ_FAAP20 PF15750.5 CCD24098.1 - 0.15 12.0 0.9 0.68 9.9 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Prok-RING_1 PF14446.6 CCD24098.1 - 0.32 10.9 20.6 0.6 10.1 5.0 4.2 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 zf-AN1 PF01428.16 CCD24098.1 - 5.3 7.3 26.7 0.94 9.7 8.4 3.8 4 1 0 4 4 3 0 AN1-like Zinc finger HypA PF01155.19 CCD24098.1 - 6.1 6.9 14.9 3.7 7.6 2.1 3.4 2 1 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HC_2 PF13913.6 CCD24098.1 - 8 6.5 17.7 2 8.4 0.0 4.7 5 1 0 5 5 5 0 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.6 CCD24098.1 - 8.2 6.5 10.0 9 6.3 0.0 4.1 3 1 0 3 3 3 0 zinc-ribbon domain WD40 PF00400.32 CCD24099.1 - 1.3e-14 54.3 11.8 0.29 12.1 0.1 8.3 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD24099.1 - 1e-08 35.4 5.6 0.045 14.0 0.1 6.2 3 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCD24099.1 - 0.05 12.9 8.0 0.65 9.3 0.3 4.5 3 2 2 5 5 5 0 WD40-like domain DUF1921 PF09081.10 CCD24099.1 - 2.8 8.2 4.9 16 5.8 0.1 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF1921) Cnd3 PF12719.7 CCD24100.1 - 4.4e-91 305.1 4.8 4.4e-91 305.1 4.8 2.5 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 CCD24100.1 - 4e-05 23.5 0.1 0.65 10.4 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 CCD24100.1 - 0.0035 17.7 0.0 0.5 10.8 0.0 3.7 2 1 1 3 3 3 2 HEAT repeats CNOT11 PF10155.9 CCD24100.1 - 0.012 15.7 2.5 1.2 9.4 0.0 4.0 2 1 1 3 3 3 0 CCR4-NOT transcription complex subunit 11 DUF5071 PF16804.5 CCD24100.1 - 1.6 9.0 6.6 12 6.1 0.1 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF5071) VASt PF16016.5 CCD24101.1 - 1.2e-71 240.1 3.7 1.7e-35 122.7 0.3 3.0 3 0 0 3 3 3 2 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CCD24101.1 - 2.1e-28 98.5 0.1 4.2e-28 97.5 0.1 1.6 1 0 0 1 1 1 1 GRAM domain zf-CCCH_7 PF18586.1 CCD24101.1 - 1.4 9.3 4.1 2.2 8.6 0.0 3.4 4 0 0 4 4 4 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Skp1 PF01466.19 CCD24102.1 - 6.5e-25 87.0 0.1 1.3e-24 86.0 0.1 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CCD24102.1 - 3.5e-15 55.9 0.3 1.7e-07 31.3 0.2 2.5 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain Peroxin-3 PF04882.12 CCD24103.1 - 1.7e-81 274.7 20.1 4.8e-64 217.1 13.0 2.0 1 1 1 2 2 2 2 Peroxin-3 CBP_GIL PF10995.8 CCD24103.1 - 0.034 12.8 0.0 0.089 11.5 0.0 1.7 1 0 0 1 1 1 0 Cellulose biosynthesis GIL Thioredoxin_7 PF13899.6 CCD24104.1 - 6.4e-23 80.8 0.0 1.2e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 CCD24104.1 - 4.7e-15 55.1 0.2 1.1e-14 54.0 0.2 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 CCD24104.1 - 1.3e-14 54.2 0.0 3.2e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 UBX domain C2-set PF05790.15 CCD24104.1 - 0.00014 21.9 0.0 0.00037 20.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin C2-set domain Thioredox_DsbH PF03190.15 CCD24104.1 - 0.043 13.8 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 CCD24104.1 - 0.092 13.2 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Peptidase_C13 PF01650.18 CCD24105.1 - 1.5e-47 162.2 0.4 2e-47 161.9 0.4 1.1 1 0 0 1 1 1 1 Peptidase C13 family Alpha_adaptin_C PF02296.16 CCD24105.1 - 0.11 12.7 0.2 6.9 6.9 0.1 2.3 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain ResIII PF04851.15 CCD24106.1 - 2.3e-28 99.3 5.1 7.5e-28 97.7 0.2 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCD24106.1 - 6.7e-20 71.6 0.1 1.8e-19 70.2 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD24106.1 - 1.5e-14 54.3 2.5 4.7e-13 49.5 0.2 3.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 CCD24106.1 - 3.7e-09 36.6 0.8 3.7e-09 36.6 0.8 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 CCD24106.1 - 8.2e-06 26.1 0.4 0.00032 21.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 CCD24106.1 - 3.7e-05 23.1 0.1 8.4e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.23 CCD24106.1 - 0.013 14.2 1.0 0.038 12.7 0.0 2.2 3 0 0 3 3 3 0 SNF2 family N-terminal domain Flavi_DEAD PF07652.14 CCD24106.1 - 0.013 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_11 PF13086.6 CCD24106.1 - 0.048 13.5 3.4 0.55 10.0 0.1 3.0 2 1 1 3 3 3 0 AAA domain TMA7 PF09072.10 CCD24106.1 - 3.6 8.5 6.6 5.5 7.9 5.6 1.8 2 0 0 2 2 2 0 Translation machinery associated TMA7 STE PF02200.16 CCD24107.1 - 5e-59 197.5 2.4 8.9e-59 196.7 2.4 1.4 1 0 0 1 1 1 1 STE like transcription factor Tcf25 PF04910.14 CCD24108.1 - 2.7e-86 289.8 1.7 4.5e-86 289.1 1.7 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TraE PF05309.11 CCD24108.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 TraE protein ARD PF03079.14 CCD24108.1 - 0.64 10.2 8.0 2 8.6 8.0 1.8 1 0 0 1 1 1 0 ARD/ARD' family GET2 PF08690.10 CCD24108.1 - 6.8 6.3 13.8 3.2 7.4 1.1 2.5 1 1 1 2 2 2 0 GET complex subunit GET2 Ipi1_N PF12333.8 CCD24109.1 - 1.5e-24 86.5 0.1 1.5e-24 86.5 0.1 2.4 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation UCH PF00443.29 CCD24109.1 - 0.026 14.0 0.2 0.035 13.6 0.2 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Oxidored_FMN PF00724.20 CCD24110.1 - 3.1e-11 43.1 0.0 3.7e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SNF2_N PF00176.23 CCD24111.1 - 5.1e-67 226.1 0.2 1e-66 225.1 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCD24111.1 - 1.5e-18 67.1 0.1 1e-17 64.4 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 CCD24111.1 - 4.8e-18 65.2 5.8 4.8e-18 65.2 5.8 2.1 1 1 0 1 1 1 1 HSA ResIII PF04851.15 CCD24111.1 - 2.8e-11 43.7 0.0 2.8e-11 43.7 0.0 3.8 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCD24111.1 - 1.5e-06 28.1 0.0 1.2e-05 25.1 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 CCD24112.1 - 2.9e-12 46.7 0.0 6.7e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCD24112.1 - 1.2e-05 25.3 0.0 5.9e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 CCD24112.1 - 0.0018 17.7 0.0 0.0039 16.6 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CCD24112.1 - 0.016 14.8 0.7 0.045 13.3 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CCD24112.1 - 0.062 12.8 0.1 0.15 11.6 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B NRIP1_repr_1 PF15687.5 CCD24112.1 - 0.099 12.3 0.3 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 1 Ribosomal_S15 PF00312.22 CCD24113.1 - 2.5e-30 104.5 0.8 2.5e-30 104.5 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 HAD_SAK_2 PF18143.1 CCD24113.1 - 0.014 15.7 1.4 3.1 8.1 0.2 2.2 2 0 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins FHIPEP PF00771.20 CCD24113.1 - 0.066 11.7 1.5 0.079 11.4 1.5 1.0 1 0 0 1 1 1 0 FHIPEP family UPF0542 PF15086.6 CCD24113.1 - 1.1 9.3 5.1 0.42 10.6 1.3 2.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 Syntaxin-18_N PF10496.9 CCD24113.1 - 3.4 8.0 7.2 1.6 9.0 1.7 2.6 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus MatE PF01554.18 CCD24114.1 - 6.8e-63 211.1 34.3 8.6e-40 136.0 9.9 3.2 3 0 0 3 3 3 2 MatE Fcf1 PF04900.12 CCD24115.1 - 3.3e-34 117.2 0.2 3.3e-34 117.2 0.2 1.5 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 CCD24115.1 - 6.9e-14 52.2 0.0 1.1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 PIN like domain Imm-NTF2 PF15655.6 CCD24115.1 - 0.0076 16.5 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 NTF2 fold immunity protein Sugar_tr PF00083.24 CCD24116.1 - 4.5e-173 576.3 36.7 5.1e-173 576.1 36.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD24116.1 - 1.1e-26 93.6 31.6 2.2e-26 92.7 22.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.7 CCD24116.1 - 0.005 17.0 4.0 0.005 17.0 4.0 5.5 3 2 2 5 5 5 1 Protein of unknown function (DUF3792) DUF4383 PF14325.6 CCD24116.1 - 3 8.1 12.7 0.85 9.9 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4383) Gate PF07670.14 CCD24116.1 - 6.7 7.0 10.4 1.8 8.9 0.8 2.9 2 0 0 2 2 2 0 Nucleoside recognition Sugar_tr PF00083.24 CCD24117.1 - 7.4e-170 565.7 33.9 8.5e-170 565.5 33.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD24117.1 - 1.3e-30 106.6 32.7 2.7e-29 102.2 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.16 CCD24117.1 - 0.65 9.5 5.1 1.3 8.5 1.4 3.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Svf1 PF08622.10 CCD24118.1 - 4.8e-68 228.4 1.4 8.7e-68 227.5 1.4 1.5 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 CCD24118.1 - 6e-66 221.3 1.0 1.3e-65 220.2 1.0 1.6 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain DUF913 PF06025.12 CCD24118.1 - 0.12 11.3 1.1 0.19 10.7 1.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CCD24118.1 - 0.38 9.5 4.1 0.1 11.3 1.1 1.6 2 0 0 2 2 2 0 Presenilin Roughex PF06020.11 CCD24118.1 - 0.52 9.4 6.8 0.83 8.7 6.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein PTPRCAP PF15713.5 CCD24118.1 - 0.58 10.4 13.3 1.2 9.4 13.3 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Connexin PF00029.19 CCD24118.1 - 0.71 9.6 3.7 1.1 9.0 3.7 1.2 1 0 0 1 1 1 0 Connexin Zip PF02535.22 CCD24118.1 - 1 8.5 2.5 1.7 7.8 2.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter LRRC37AB_C PF14914.6 CCD24118.1 - 1.9 8.4 7.3 3.7 7.5 7.3 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain FAM176 PF14851.6 CCD24118.1 - 2.3 7.9 8.3 6 6.5 8.3 1.7 1 0 0 1 1 1 0 FAM176 family DUF4820 PF16091.5 CCD24118.1 - 2.8 7.2 6.6 5.1 6.4 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DNA_pol_phi PF04931.13 CCD24118.1 - 3.2 5.8 12.7 4.8 5.2 12.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 CCD24118.1 - 3.7 6.8 10.1 6.9 5.9 10.1 1.4 1 0 0 1 1 1 0 NOA36 protein O-antigen_lig PF13425.6 CCD24118.1 - 5.3 5.7 5.6 9 5.0 5.6 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein FYDLN_acid PF09538.10 CCD24118.1 - 7.1 7.4 13.7 3.4 8.4 9.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) CPSF100_C PF13299.6 CCD24118.1 - 8.5 6.5 9.0 2 8.6 5.6 1.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Sod_Fe_C PF02777.18 CCD24119.1 - 1.9e-13 50.4 1.3 1.7e-06 28.1 0.1 3.0 2 1 1 3 3 3 2 Iron/manganese superoxide dismutases, C-terminal domain Semialdhyde_dhC PF02774.18 CCD24119.1 - 0.062 13.4 0.0 0.089 12.9 0.0 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain DUF1666 PF07891.12 CCD24119.1 - 0.28 10.8 1.9 0.29 10.7 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1666) Pal1 PF08316.11 CCD24120.1 - 1.2e-48 165.3 3.7 1.2e-48 165.3 3.7 3.9 2 1 2 4 4 4 1 Pal1 cell morphology protein SRP72 PF08492.12 CCD24120.1 - 0.092 13.2 9.3 0.41 11.1 9.3 2.2 1 1 0 1 1 1 0 SRP72 RNA-binding domain VIR_N PF15912.5 CCD24120.1 - 1.7 8.2 17.5 3.8 7.0 17.5 1.6 1 0 0 1 1 1 0 Virilizer, N-terminal SelP_N PF04592.14 CCD24120.1 - 4.8 6.5 11.5 10 5.4 11.5 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Asp PF00026.23 CCD24121.1 - 1.6e-31 109.9 4.8 1.3e-29 103.7 4.8 2.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCD24121.1 - 0.00015 22.1 2.5 0.00079 19.7 0.6 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal FAT PF02259.23 CCD24122.1 - 4e-71 240.0 8.3 9.7e-71 238.8 8.3 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 CCD24122.1 - 2.1e-47 162.0 0.6 2.1e-47 162.0 0.6 2.6 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase U62_UL91 PF17442.2 CCD24122.1 - 0.046 13.7 3.2 6.5 6.8 0.0 3.8 3 0 0 3 3 3 0 Functional domain of U62 and UL91 proteins HEAT PF02985.22 CCD24122.1 - 0.094 13.0 0.3 1.6 9.2 0.1 3.0 2 0 0 2 2 2 0 HEAT repeat FATC PF02260.20 CCD24122.1 - 0.11 12.4 0.0 0.39 10.6 0.0 2.1 1 0 0 1 1 1 0 FATC domain DUF2097 PF09870.9 CCD24122.1 - 0.27 11.5 1.4 34 4.7 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2097) PXA PF02194.15 CCD24122.1 - 0.95 9.4 6.0 1.8 8.5 0.2 3.7 3 0 0 3 3 3 0 PXA domain SBE2 PF17076.5 CCD24124.1 - 1.2e-138 463.8 89.3 4.7e-129 432.0 59.1 4.0 1 1 1 2 2 2 2 SBE2, cell-wall formation DUF111 PF01969.17 CCD24124.1 - 0.059 12.5 0.1 0.096 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF111 PQ-loop PF04193.14 CCD24125.1 - 2.6e-35 120.0 11.5 2.7e-17 62.3 1.2 2.7 2 0 0 2 2 2 2 PQ loop repeat ECF_trnsprt PF12822.7 CCD24125.1 - 0.00055 20.1 2.7 0.0029 17.7 2.7 1.9 1 1 0 1 1 1 1 ECF transporter, substrate-specific component MtN3_slv PF03083.16 CCD24125.1 - 0.073 13.1 6.0 0.65 10.1 0.4 3.2 2 2 1 3 3 3 0 Sugar efflux transporter for intercellular exchange Pyr_redox_2 PF07992.14 CCD24126.1 - 5.7e-49 166.9 0.1 6.6e-49 166.7 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCD24126.1 - 6.2e-20 71.6 0.3 1e-15 58.1 0.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCD24126.1 - 3.6e-13 49.4 0.0 2.3e-11 43.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCD24126.1 - 1.7e-05 24.2 0.0 0.00012 21.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 CCD24126.1 - 6.4e-05 23.3 0.0 0.028 14.8 0.0 2.3 2 0 0 2 2 2 2 Putative NAD(P)-binding GIDA PF01134.22 CCD24126.1 - 6.9e-05 22.1 1.8 0.29 10.2 0.0 3.5 3 1 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CCD24126.1 - 0.00033 20.8 0.1 0.018 15.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 CCD24126.1 - 0.0015 18.6 0.1 1.1 9.3 0.0 2.6 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 CCD24126.1 - 0.0084 15.3 0.1 5.4 6.1 0.0 3.6 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 CCD24126.1 - 0.0095 15.2 0.0 2.9 7.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 CCD24126.1 - 0.059 12.4 2.7 2 7.4 0.3 2.5 2 1 0 3 3 3 0 FAD binding domain DEAD PF00270.29 CCD24127.1 - 5.1e-38 130.6 0.1 1.3e-37 129.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD24127.1 - 2.2e-20 73.1 0.0 1.1e-19 70.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD24127.1 - 2.8e-06 27.5 0.0 6.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CK2S PF15011.6 CCD24128.1 - 0.038 13.9 0.1 0.082 12.8 0.1 1.6 1 0 0 1 1 1 0 Casein Kinase 2 substrate DUF936 PF06075.12 CCD24128.1 - 0.063 12.2 38.6 0.096 11.6 38.6 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) CoaE PF01121.20 CCD24129.1 - 6.4e-61 205.1 0.0 8e-61 204.8 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 CCD24129.1 - 4.7e-06 27.2 0.1 1.6e-05 25.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CCD24129.1 - 1.2e-05 25.6 0.0 3e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 CCD24129.1 - 2.4e-05 24.5 0.1 0.00023 21.3 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.6 CCD24129.1 - 9.4e-05 22.6 0.0 0.00019 21.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CCD24129.1 - 0.00019 21.8 0.1 0.00057 20.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 CCD24129.1 - 0.00085 19.5 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase-like family dNK PF01712.19 CCD24129.1 - 0.0029 17.5 0.2 0.052 13.4 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase PRK PF00485.18 CCD24129.1 - 0.0071 16.1 0.1 0.094 12.4 0.0 2.2 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family tRNA_lig_kinase PF08303.11 CCD24129.1 - 0.015 15.4 0.1 0.033 14.3 0.0 1.6 2 0 0 2 2 2 0 tRNA ligase kinase domain AAA_14 PF13173.6 CCD24129.1 - 0.016 15.3 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ALC PF17527.2 CCD24129.1 - 0.034 13.8 0.7 0.056 13.1 0.7 1.3 1 0 0 1 1 1 0 Phage ALC protein ABC_tran PF00005.27 CCD24129.1 - 0.045 14.3 0.2 0.08 13.5 0.3 1.7 1 1 0 1 1 1 0 ABC transporter Cytidylate_kin PF02224.18 CCD24129.1 - 0.049 13.4 0.0 0.088 12.5 0.0 1.7 1 1 0 1 1 1 0 Cytidylate kinase AAA_22 PF13401.6 CCD24129.1 - 0.087 13.1 0.0 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain ApbA_C PF08546.11 CCD24130.1 - 2.6e-11 43.8 0.3 4.5e-11 43.0 0.3 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DUF2188 PF09954.9 CCD24130.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) SET PF00856.28 CCD24131.1 - 0.15 12.4 0.1 0.56 10.6 0.0 2.1 2 1 0 2 2 2 0 SET domain FHA PF00498.26 CCD24132.1 - 5.3e-18 65.1 0.4 2.1e-17 63.2 0.4 2.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CCD24132.1 - 1.2e-05 25.5 0.0 4.6e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 CCD24132.1 - 0.013 15.7 0.0 0.069 13.4 0.0 2.2 1 0 0 1 1 1 0 FHA domain Tir_receptor_N PF07490.11 CCD24132.1 - 0.018 14.9 0.8 0.04 13.8 0.8 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus TFR_dimer PF04253.15 CCD24132.1 - 0.064 13.4 0.3 0.16 12.0 0.3 1.7 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain DASH_Spc19 PF08287.11 CCD24133.1 - 1.5e-38 132.1 11.9 1.7e-38 132.0 11.9 1.0 1 0 0 1 1 1 1 Spc19 DUF1319 PF07028.11 CCD24133.1 - 0.14 12.4 4.8 6.2 7.1 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1319) Noelin-1 PF12308.8 CCD24133.1 - 0.53 10.3 5.3 3 7.9 0.3 2.8 1 1 0 3 3 3 0 Neurogenesis glycoprotein Phage_GP20 PF06810.11 CCD24133.1 - 0.7 9.7 0.1 0.7 9.7 0.1 3.0 2 1 0 2 2 2 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 CCD24133.1 - 0.85 10.1 6.2 11 6.6 2.0 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 CCD24133.1 - 0.87 9.8 9.8 1 9.5 5.6 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin PF02996.17 CCD24133.1 - 1.1 9.2 8.9 1 9.3 0.5 3.0 3 0 0 3 3 3 0 Prefoldin subunit GIT_CC PF16559.5 CCD24133.1 - 1.6 8.7 12.7 4.5 7.2 0.0 3.6 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 CCD24133.1 - 1.8 9.1 13.3 5.2 7.6 1.9 3.2 2 1 0 2 2 2 0 Cell division protein ZapB Sas6_CC PF18594.1 CCD24133.1 - 5.1 7.0 8.0 3.6 7.4 1.7 2.5 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain Coq4 PF05019.13 CCD24134.1 - 6.5e-92 306.8 0.0 1e-91 306.2 0.0 1.3 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Transp_cyt_pur PF02133.15 CCD24135.1 - 2.3e-70 237.6 44.0 2.9e-70 237.2 44.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cation_efflux PF01545.21 CCD24136.1 - 1.9e-41 142.0 7.1 1.9e-41 142.0 7.1 3.6 4 0 0 4 4 4 1 Cation efflux family SPX PF03105.19 CCD24136.1 - 1.7 8.5 7.1 0.4 10.6 0.7 2.1 2 0 0 2 2 2 0 SPX domain DUF4766 PF15973.5 CCD24136.1 - 5.9 7.5 11.8 2.2 8.9 8.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4766) EST1_DNA_bind PF10373.9 CCD24137.1 - 4.5e-42 144.5 13.9 4.5e-42 144.5 13.9 2.1 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 CCD24137.1 - 2.1e-22 80.2 1.0 2.1e-22 80.2 1.0 3.9 6 0 0 6 6 6 1 Telomerase activating protein Est1 Zn_clus PF00172.18 CCD24138.1 - 1.7e-08 34.5 9.4 3.1e-08 33.6 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytokin_check_N PF10407.9 CCD24138.1 - 0.004 17.1 1.1 0.011 15.7 1.1 1.8 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus PIP5K PF01504.18 CCD24139.1 - 2.8e-95 318.7 6.2 2.8e-95 318.7 6.2 3.2 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Androgen_recep PF02166.16 CCD24139.1 - 0.81 8.5 4.2 7.5 5.3 0.7 2.1 2 0 0 2 2 2 0 Androgen receptor W2 PF02020.18 CCD24140.1 - 9.6e-15 54.5 4.8 9.6e-15 54.5 4.8 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 CCD24140.1 - 2e-10 40.0 24.2 0.00027 20.6 3.1 4.9 3 2 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 CCD24140.1 - 3.6e-09 36.6 0.0 6.7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 CCD24140.1 - 3.4e-07 28.8 1.0 3.4e-07 28.8 1.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 CCD24140.1 - 8.9e-05 21.6 7.1 0.009 15.0 1.3 2.2 1 1 1 2 2 2 2 L-fucokinase NTP_transf_3 PF12804.7 CCD24140.1 - 0.0066 16.8 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 CCD24140.1 - 0.094 12.6 0.2 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 Cytidylyltransferase Ras PF00071.22 CCD24141.1 - 3.4e-48 163.3 0.0 4e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD24141.1 - 1.3e-17 64.1 0.0 1.9e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD24141.1 - 4.1e-06 26.4 0.0 5.4e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Cpn60_TCP1 PF00118.24 CCD24142.1 - 7.1e-153 509.8 16.0 8.1e-153 509.6 16.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fungal_trans_2 PF11951.8 CCD24143.1 - 2e-11 43.3 0.2 2e-11 43.3 0.2 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD24143.1 - 2e-07 31.0 12.9 3e-07 30.4 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aha1_N PF09229.11 CCD24144.1 - 5.7e-37 127.0 0.1 5.7e-37 127.0 0.1 2.1 3 0 0 3 3 3 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 CCD24144.1 - 3.5e-13 49.9 0.1 6e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF3362 PF11842.8 CCD24144.1 - 0.039 14.3 0.9 0.083 13.2 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) LBP_C PF17386.2 CCD24144.1 - 0.84 9.6 3.8 0.78 9.7 0.3 2.7 2 0 0 2 2 2 0 Lacto-N-biose phosphorylase C-terminal domain zf-C2H2 PF00096.26 CCD24145.1 - 2.1e-11 43.6 6.4 3.7e-05 23.9 0.8 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCD24145.1 - 1.4e-07 31.6 6.8 7.7e-07 29.3 3.7 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCD24145.1 - 2.8e-07 30.8 6.2 0.0089 16.8 1.0 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CCD24145.1 - 0.0038 17.6 5.2 1.5 9.3 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCD24145.1 - 0.0073 16.6 1.0 0.42 11.0 0.2 3.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CCD24145.1 - 0.46 11.2 8.4 1.8 9.3 1.3 3.9 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats Rad9_Rad53_bind PF08605.10 CCD24146.1 - 1.5e-41 141.6 0.2 3.2e-41 140.5 0.2 1.6 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.26 CCD24146.1 - 3e-09 37.1 0.1 1.3e-08 35.1 0.1 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CCD24146.1 - 9.8e-07 29.1 0.1 1.7e-05 25.2 0.0 3.1 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CCD24146.1 - 3.9e-05 23.5 0.0 0.00013 21.8 0.0 1.9 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Septin PF00735.18 CCD24147.1 - 1.2e-66 224.9 10.7 1.8e-66 224.3 10.7 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CCD24147.1 - 0.00016 21.7 1.2 0.001 19.2 1.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCD24147.1 - 0.00095 19.1 1.3 0.011 15.6 0.0 2.9 2 1 1 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 CCD24147.1 - 0.0045 17.0 0.5 0.013 15.5 0.3 2.1 1 1 0 1 1 1 1 Dynamin family AAA_7 PF12775.7 CCD24147.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 CCD24147.1 - 0.0058 17.1 0.6 0.032 14.8 0.0 2.3 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 CCD24147.1 - 0.0075 16.7 0.0 0.036 14.5 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 CCD24147.1 - 0.011 16.0 0.0 0.035 14.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CCD24147.1 - 0.012 15.9 0.0 0.032 14.4 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 CCD24147.1 - 0.018 14.4 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MCM PF00493.23 CCD24147.1 - 0.022 13.8 0.2 0.09 11.9 0.0 2.0 2 0 0 2 2 2 0 MCM P-loop domain AAA_5 PF07728.14 CCD24147.1 - 0.023 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCD24147.1 - 0.033 14.6 0.0 0.063 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CCD24147.1 - 0.035 13.8 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CCD24147.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 CCD24147.1 - 0.071 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 CCD24147.1 - 0.072 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 CCD24147.1 - 0.092 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein GTP_EFTU PF00009.27 CCD24147.1 - 0.44 10.1 4.7 0.94 9.0 0.1 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain F-box PF00646.33 CCD24148.1 - 1.2e-05 25.0 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CCD24148.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 CCD24148.1 - 0.013 15.4 0.9 0.021 14.7 0.1 1.8 2 0 0 2 2 2 0 F-box PRKCSH-like PF12999.7 CCD24149.1 - 1.1e-36 126.3 4.5 1.1e-36 126.3 4.5 2.4 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CCD24149.1 - 8.1e-16 58.1 1.4 8.1e-16 58.1 1.4 3.1 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 CCD24149.1 - 3.5 7.9 15.1 9.9 6.5 3.5 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Svf1_C PF17187.4 CCD24150.1 - 3.2e-42 144.2 1.3 5.5e-42 143.4 1.3 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 CCD24150.1 - 9.5e-41 139.6 1.2 4e-40 137.5 1.2 2.0 1 1 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Secretin_N_2 PF07655.13 CCD24150.1 - 5.2 7.7 13.9 4.7 7.8 8.7 3.0 3 1 0 3 3 3 0 Secretin N-terminal domain VIT1 PF01988.19 CCD24151.1 - 4.4e-62 209.8 0.2 6.1e-62 209.3 0.2 1.2 1 0 0 1 1 1 1 VIT family KdpC PF02669.15 CCD24151.1 - 3.9 7.3 7.3 1.8 8.4 1.7 2.2 2 0 0 2 2 2 0 K+-transporting ATPase, c chain Histone PF00125.24 CCD24152.1 - 3.3e-21 76.0 4.5 4e-21 75.7 4.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCD24152.1 - 7.8e-06 26.1 0.1 1.6e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CCD24152.1 - 0.0016 18.9 0.0 0.0028 18.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 CCD24152.1 - 0.0019 18.4 0.0 0.0029 17.8 0.0 1.2 1 0 0 1 1 1 1 CENP-W protein YscO-like PF16789.5 CCD24152.1 - 0.013 15.6 0.7 0.014 15.4 0.7 1.1 1 0 0 1 1 1 0 YscO-like protein Histone_H2A_C PF16211.5 CCD24153.1 - 3.7e-21 74.6 1.1 6.1e-21 73.9 1.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CCD24153.1 - 1.7e-17 64.0 0.0 2.3e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCD24153.1 - 7.7e-06 26.1 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LcrG PF07216.12 CCD24153.1 - 0.043 13.7 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 LcrG protein ADK PF00406.22 CCD24154.1 - 2e-61 206.5 0.0 2.3e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CCD24154.1 - 1.4e-25 90.3 0.1 3e-25 89.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CCD24154.1 - 1.5e-17 63.3 0.0 3.6e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 CCD24154.1 - 1.5e-07 31.6 0.0 3.5e-07 30.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCD24154.1 - 1.8e-05 25.3 0.0 4.4e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 CCD24154.1 - 0.00036 20.9 0.1 0.0011 19.3 0.0 1.7 1 1 1 2 2 2 1 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 CCD24154.1 - 0.01 15.6 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_24 PF13479.6 CCD24154.1 - 0.034 13.9 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 CCD24154.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase Zeta_toxin PF06414.12 CCD24154.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 CCD24154.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain SIR4_SID PF16991.5 CCD24155.1 - 4.5e-58 195.9 1.2 4.5e-58 195.9 1.2 7.7 9 2 2 11 11 11 2 Sir4 SID domain CFIA_Pcf11 PF11526.8 CCD24157.1 - 2e-35 121.1 5.5 2e-35 121.1 5.5 3.1 4 0 0 4 4 4 1 Subunit of cleavage factor IA Pcf11 VHS PF00790.19 CCD24157.1 - 0.00098 19.0 0.2 0.0043 16.9 0.0 2.2 2 0 0 2 2 2 1 VHS domain CTD_bind PF04818.13 CCD24157.1 - 0.001 19.9 0.7 0.0034 18.2 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase II-binding domain. TMEM43 PF07787.12 CCD24157.1 - 0.13 11.7 4.9 0.24 10.7 4.9 1.4 1 0 0 1 1 1 0 Transmembrane protein 43 Borrelia_REV PF03978.13 CCD24157.1 - 0.28 11.1 3.6 0.94 9.4 3.6 1.9 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein zf-C2HC_2 PF13913.6 CCD24157.1 - 2 8.4 4.0 14 5.7 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 CCD24157.1 - 2.3 8.3 5.7 6.2 6.9 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger ASFV_J13L PF05568.11 CCD24157.1 - 5.1 6.8 6.6 1.2 8.9 0.4 2.2 2 0 0 2 2 2 0 African swine fever virus J13L protein zf_UBZ PF18439.1 CCD24157.1 - 7.7 6.2 9.4 43 3.8 4.7 3.0 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF3298 PF11738.8 CCD24158.1 - 0.14 13.2 1.4 0.81 10.8 1.4 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3298) 5_3_exonuc PF01367.20 CCD24158.1 - 0.16 12.6 2.5 0.38 11.4 1.4 2.3 1 1 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DUF3767 PF12597.8 CCD24159.1 - 6e-35 119.1 0.2 1e-34 118.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Methyltransf_20 PF12147.8 CCD24159.1 - 0.05 12.7 0.0 0.067 12.3 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase Aminotran_1_2 PF00155.21 CCD24160.1 - 1.6e-70 238.1 0.2 3.3e-70 237.1 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CCD24160.1 - 9.3e-09 34.3 0.0 1.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CCD24160.1 - 9.1e-05 21.9 0.2 0.00022 20.7 0.2 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CCD24160.1 - 0.00045 19.3 0.0 0.0022 17.0 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CCD24160.1 - 0.0093 15.3 0.0 0.021 14.1 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Mucin PF01456.17 CCD24160.1 - 0.25 11.3 11.5 0.43 10.6 11.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Alpha_GJ PF03229.13 CCD24160.1 - 0.95 10.0 9.1 2 9.0 9.1 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J Reticulon PF02453.17 CCD24161.1 - 4.9e-36 124.1 4.4 7.5e-36 123.5 4.4 1.3 1 0 0 1 1 1 1 Reticulon NUC130_3NT PF08158.12 CCD24161.1 - 0.094 13.0 2.5 0.67 10.3 0.2 2.5 2 0 0 2 2 2 0 NUC130/3NT domain APC_N_CC PF16689.5 CCD24161.1 - 0.15 12.2 5.8 0.24 11.5 1.3 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Aconitase PF00330.20 CCD24162.1 - 1.7e-109 366.9 0.1 1.4e-108 363.8 0.1 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCD24162.1 - 4.5e-33 114.3 1.4 7.8e-33 113.6 0.0 2.1 3 0 0 3 3 3 1 Aconitase C-terminal domain Flavokinase PF01687.17 CCD24164.1 - 3.3e-26 91.8 0.0 4.1e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Ribosomal_L5_C PF00673.21 CCD24165.1 - 1.3e-27 95.8 0.0 3e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CCD24165.1 - 7.1e-14 51.9 0.0 1.7e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 Adaptin_N PF01602.20 CCD24166.1 - 1.1e-105 354.2 16.2 2e-105 353.4 16.2 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 CCD24166.1 - 5.1e-53 178.7 0.6 1.5e-52 177.2 0.6 1.9 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 CCD24166.1 - 4.7e-52 175.3 0.0 1.2e-51 174.0 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 CCD24166.1 - 7.9e-06 26.0 0.2 7.9e-06 26.0 0.2 3.5 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCD24166.1 - 1.1e-05 25.8 6.4 0.92 9.9 0.0 4.8 2 1 2 5 5 5 3 HEAT repeats HEAT PF02985.22 CCD24166.1 - 0.0025 17.9 1.4 6.4 7.3 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Alpha_adaptinC2 PF02883.20 CCD24166.1 - 0.025 14.9 0.1 0.063 13.6 0.1 1.6 1 0 0 1 1 1 0 Adaptin C-terminal domain DUF5578 PF17741.1 CCD24166.1 - 0.057 12.8 9.2 2.7 7.3 0.4 4.0 2 2 2 4 4 4 0 Family of unknown function (DUF5578) TAF6_C PF07571.13 CCD24166.1 - 0.13 12.7 0.0 0.61 10.4 0.0 2.3 1 1 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain Ino80_Iec3 PF14612.6 CCD24168.1 - 0.021 15.5 5.1 0.038 14.7 5.1 1.3 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling SRI PF08236.11 CCD24168.1 - 0.031 14.4 0.8 0.1 12.8 0.1 2.2 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Ribosomal_L7Ae PF01248.26 CCD24169.1 - 2.9e-27 94.2 0.6 4.5e-27 93.6 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3692 PF12469.8 CCD24169.1 - 0.21 11.8 0.6 1.5 9.1 0.1 2.1 1 1 1 2 2 2 0 CRISPR-associated protein Amidase PF01425.21 CCD24170.1 - 1.3e-89 301.2 0.0 1.6e-89 301.0 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF1160 PF06648.11 CCD24170.1 - 0.067 13.2 0.4 0.16 12.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) DEAD PF00270.29 CCD24171.1 - 5.2e-45 153.4 1.7 3.6e-44 150.6 0.1 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD24171.1 - 1.3e-30 106.0 1.6 1.1e-28 99.8 0.3 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD24171.1 - 1.7e-09 37.9 0.2 4.5e-08 33.3 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3788 PF12663.7 CCD24171.1 - 0.0072 16.3 0.2 0.026 14.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3788) AAA_22 PF13401.6 CCD24171.1 - 0.026 14.8 2.7 0.069 13.4 0.1 2.8 3 0 0 3 3 3 0 AAA domain CdiA_C PF18451.1 CCD24171.1 - 0.067 13.4 0.6 0.4 10.9 0.1 2.6 2 0 0 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain TPR_11 PF13414.6 CCD24172.1 - 5.9e-18 64.3 6.0 5.4e-07 29.2 0.1 5.4 3 1 2 5 5 5 3 TPR repeat TPR_1 PF00515.28 CCD24172.1 - 1e-17 63.1 10.3 8e-07 28.6 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCD24172.1 - 1.2e-17 62.5 8.0 7.3e-05 22.6 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 CCD24172.1 - 1.9e-13 50.0 0.1 0.0019 18.9 0.0 4.9 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCD24172.1 - 4.4e-13 48.6 14.5 0.00095 19.4 0.1 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 CCD24172.1 - 6.3e-11 41.6 10.1 0.0025 17.9 0.1 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CCD24172.1 - 3e-10 40.6 0.0 0.00084 19.9 0.1 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 CCD24172.1 - 1.8e-09 37.6 0.0 0.0019 18.3 0.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.6 CCD24172.1 - 8.2e-09 35.7 1.5 0.0018 18.6 0.0 4.6 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCD24172.1 - 2.1e-07 31.3 5.1 0.018 15.6 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CCD24172.1 - 1.7e-06 28.3 0.3 3.2 8.6 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCD24172.1 - 3.3e-05 24.1 2.0 0.046 14.0 0.9 3.5 1 1 2 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD24172.1 - 4.3e-05 23.7 5.3 0.026 14.7 0.1 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CCD24172.1 - 0.0067 15.7 0.9 0.026 13.8 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 CCD24172.1 - 0.011 16.2 0.1 0.22 11.9 0.0 2.3 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_7 PF13176.6 CCD24172.1 - 0.018 15.0 0.0 17 5.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 CCD24172.1 - 0.043 13.9 0.1 20 5.3 0.0 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 CCD24172.1 - 0.18 11.9 1.3 4 7.6 0.0 3.1 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 CCD24172.1 - 0.6 10.1 6.6 7 6.7 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_transf_34 PF05637.12 CCD24173.1 - 1.2e-72 244.5 0.2 1.7e-72 244.0 0.2 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Sybindin PF04099.12 CCD24174.1 - 6.2e-35 120.2 5.1 4.2e-14 52.7 0.6 3.0 2 1 1 3 3 3 3 Sybindin-like family Sedlin_N PF04628.13 CCD24174.1 - 3.6e-07 30.3 1.1 5.2e-07 29.9 0.4 1.6 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region Pkinase PF00069.25 CCD24175.1 - 1.1e-45 156.1 1.3 6.3e-39 133.9 0.9 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24175.1 - 3.6e-21 75.6 0.3 1.2e-20 73.9 0.2 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD24175.1 - 6e-07 29.1 0.0 4.1e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CCD24175.1 - 0.00062 19.8 0.0 0.0016 18.4 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family APS_kinase PF01583.20 CCD24176.1 - 2.4e-07 30.8 0.0 3.2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 CCD24176.1 - 1.3e-06 28.6 0.0 1.7e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCD24176.1 - 1.7e-06 28.6 0.2 5.8e-06 26.9 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCD24176.1 - 0.00045 20.6 0.0 0.0007 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 CCD24176.1 - 0.0014 18.0 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.27 CCD24176.1 - 0.0023 18.5 0.0 0.0028 18.2 0.0 1.4 1 1 0 1 1 1 1 ABC transporter SKI PF01202.22 CCD24176.1 - 0.0032 17.6 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase CPT PF07931.12 CCD24176.1 - 0.0036 17.2 0.0 0.0057 16.5 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein T2SSE PF00437.20 CCD24176.1 - 0.0057 15.7 0.4 0.011 14.9 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 CCD24176.1 - 0.0072 16.6 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 CCD24176.1 - 0.01 15.6 0.6 0.012 15.4 0.6 1.1 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 CCD24176.1 - 0.014 14.6 0.1 0.034 13.4 0.1 1.5 1 1 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 CCD24176.1 - 0.015 14.9 0.1 0.064 12.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 CCD24176.1 - 0.024 14.3 0.3 0.042 13.6 0.3 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 CCD24176.1 - 0.03 14.0 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CCD24176.1 - 0.037 13.9 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 CCD24176.1 - 0.055 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 CCD24176.1 - 0.085 12.7 0.5 10 5.9 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF815 PF05673.13 CCD24176.1 - 0.12 11.5 0.1 0.66 9.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PRK PF00485.18 CCD24176.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family F-box-like PF12937.7 CCD24177.1 - 0.37 10.7 1.7 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 F-box-like ApbA_C PF08546.11 CCD24178.1 - 6.7e-06 26.3 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAC PF01849.18 CCD24179.1 - 1.9e-16 59.7 0.4 3.3e-16 59.0 0.1 1.6 2 0 0 2 2 2 1 NAC domain BUD22 PF09073.10 CCD24179.1 - 0.085 12.2 6.7 0.28 10.5 6.7 1.7 1 1 0 1 1 1 0 BUD22 DUF4865 PF16157.5 CCD24179.1 - 0.11 12.5 0.2 0.35 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4865) zf-C2H2_4 PF13894.6 CCD24180.1 - 3.2e-10 40.0 5.1 0.0002 21.9 1.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CCD24180.1 - 7.5e-10 38.7 7.1 9.4e-05 22.7 2.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CCD24180.1 - 3.4e-05 24.0 4.6 0.033 14.5 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CCD24180.1 - 5.2e-05 23.1 2.1 0.089 12.8 0.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CCD24180.1 - 0.0003 20.5 3.4 0.33 10.8 0.4 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 CCD24180.1 - 0.0028 18.3 8.2 0.0032 18.2 1.7 2.7 2 1 1 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 CCD24180.1 - 0.0067 16.1 0.9 0.0067 16.1 0.9 3.6 3 1 0 3 3 3 1 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 CCD24180.1 - 0.11 12.6 0.5 0.27 11.4 0.3 1.7 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2HE PF16278.5 CCD24180.1 - 0.2 12.2 13.2 0.41 11.1 5.7 3.0 2 2 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 CCD24180.1 - 0.2 12.1 8.4 0.92 10.1 1.1 3.2 3 1 0 3 3 3 0 Zinc-finger double domain Presenilin PF01080.17 CCD24180.1 - 1.9 7.2 3.6 2.2 7.0 3.6 1.1 1 0 0 1 1 1 0 Presenilin LicD PF04991.13 CCD24180.1 - 7.2 6.7 14.4 1.5 8.9 11.3 1.4 2 0 0 2 2 2 0 LicD family CLTH PF10607.9 CCD24181.1 - 8.9e-13 48.4 1.9 8.9e-13 48.4 1.9 2.4 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 CCD24181.1 - 1.4e-05 25.0 0.3 4e-05 23.5 0.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CCD24181.1 - 0.068 13.1 0.4 0.17 11.9 0.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DUF4083 PF13314.6 CCD24181.1 - 0.085 12.8 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) zf-C3HC4_4 PF15227.6 CCD24181.1 - 0.11 12.7 0.1 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CCD24181.1 - 0.19 12.1 0.8 0.43 11.0 0.8 1.6 1 0 0 1 1 1 0 Ring finger domain Catalase PF00199.19 CCD24182.1 - 2e-178 593.4 0.4 2.5e-178 593.0 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CCD24182.1 - 3.4e-11 43.2 0.0 1.4e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive NOA36 PF06524.12 CCD24183.1 - 3.4 6.9 23.3 1.3 8.3 18.5 2.4 2 0 0 2 2 2 0 NOA36 protein Anp1 PF03452.14 CCD24184.1 - 5.7e-94 314.4 1.1 6.8e-94 314.2 1.1 1.1 1 0 0 1 1 1 1 Anp1 Staphopain_pro PF14731.6 CCD24184.1 - 0.26 11.3 3.4 6.6 6.7 0.3 2.3 2 0 0 2 2 2 0 Staphopain proregion Alk_phosphatase PF00245.20 CCD24185.1 - 7.7e-114 380.9 0.0 9.1e-114 380.6 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CCD24185.1 - 3.6e-06 26.5 0.0 1.4e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Metalloenzyme superfamily Sigma_reg_N PF13800.6 CCD24185.1 - 0.11 12.7 0.8 0.29 11.5 0.8 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal cwf21 PF08312.12 CCD24186.1 - 7.2e-12 45.3 2.8 1.5e-11 44.2 2.8 1.6 1 0 0 1 1 1 1 cwf21 domain Glyco_transf_15 PF01793.16 CCD24187.1 - 1.8e-131 438.3 16.7 1.8e-131 438.3 16.7 1.4 1 1 1 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase TPR_1 PF00515.28 CCD24188.1 - 1.6e-09 37.1 8.6 7.6e-05 22.4 0.9 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCD24188.1 - 9.2e-09 34.8 4.1 0.012 15.7 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD24188.1 - 0.0006 20.0 2.4 0.0017 18.5 0.9 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CCD24188.1 - 0.0016 18.0 2.1 2.7 7.8 0.3 3.3 2 1 1 3 3 3 2 TPR repeat Fis1_TPR_C PF14853.6 CCD24188.1 - 0.0051 16.9 1.0 0.46 10.6 0.0 3.1 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 CCD24188.1 - 0.0056 17.2 0.1 0.03 14.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCD24188.1 - 0.051 13.9 0.6 4.4 7.7 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 CCD24188.1 - 0.079 13.4 0.5 0.35 11.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CCD24188.1 - 0.084 13.1 8.6 9.1 6.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CCD24188.1 - 0.095 13.6 0.0 16 6.7 0.0 3.5 2 2 2 4 4 4 0 Tetratricopeptide repeat RAMPs PF03787.15 CCD24188.1 - 3.3 7.7 5.4 6.3 6.8 5.4 1.6 1 1 0 1 1 1 0 RAMP superfamily INCENP_ARK-bind PF03941.15 CCD24189.1 - 6.5e-15 54.8 0.9 1.5e-14 53.7 0.9 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region ODAM PF15424.6 CCD24190.1 - 0.00025 20.7 0.0 0.00042 20.0 0.0 1.4 1 0 0 1 1 1 1 Odontogenic ameloblast-associated family DUF371 PF04027.13 CCD24190.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF371) LRR_6 PF13516.6 CCD24191.1 - 0.012 15.6 6.8 0.18 11.9 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat adh_short PF00106.25 CCD24192.1 - 2.6e-34 118.4 0.1 3.4e-34 118.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCD24192.1 - 5.3e-20 72.0 0.0 7.2e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCD24192.1 - 9.5e-07 28.9 0.0 2.2e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CCD24192.1 - 0.011 14.9 0.3 0.016 14.4 0.3 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ATP-synt_F PF01990.17 CCD24192.1 - 0.34 11.3 4.3 6.4 7.2 0.3 2.3 1 1 1 2 2 2 0 ATP synthase (F/14-kDa) subunit Pkinase PF00069.25 CCD24193.1 - 4.8e-74 249.0 0.0 5.5e-74 248.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24193.1 - 1.5e-32 113.0 0.0 1.8e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD24193.1 - 0.00016 21.1 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CCD24193.1 - 0.0004 19.4 0.1 0.0019 17.2 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CCD24193.1 - 0.001 19.1 0.0 0.014 15.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CCD24193.1 - 0.008 15.5 0.4 0.026 13.9 0.2 1.9 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CCD24193.1 - 0.052 12.6 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gly_transf_sug PF04488.15 CCD24194.1 - 2.5e-23 82.5 0.0 6.3e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF2401 PF10287.9 CCD24195.1 - 5.1e-91 304.3 1.1 5.1e-91 304.3 1.1 2.1 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CCD24195.1 - 7.5e-30 103.2 0.2 2.5e-29 101.5 0.2 2.0 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) RAMP4 PF06624.12 CCD24196.1 - 1.3e-14 54.0 0.5 1.4e-14 53.8 0.5 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Exo5 PF09810.9 CCD24197.1 - 1.7e-61 208.8 0.5 2.5e-61 208.2 0.5 1.2 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease Cas_Cas4 PF01930.17 CCD24197.1 - 6.1e-05 23.2 0.1 0.15 12.1 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 CCD24197.1 - 0.00083 19.3 1.0 1.1 9.2 0.0 3.1 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily Glutaredoxin PF00462.24 CCD24198.1 - 1.8e-15 56.9 0.0 2.8e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Amidase PF01425.21 CCD24199.1 - 2.2e-95 320.3 0.0 3.2e-95 319.7 0.0 1.2 1 0 0 1 1 1 1 Amidase CT_A_B PF02626.15 CCD24199.1 - 2e-86 289.9 0.0 4.5e-86 288.8 0.0 1.6 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 CCD24199.1 - 6.1e-64 215.4 0.0 1.2e-63 214.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 CCD24199.1 - 5.5e-45 153.6 0.0 1.1e-44 152.6 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 CCD24199.1 - 5.6e-41 139.5 0.0 1.2e-40 138.5 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CCD24199.1 - 1.6e-32 111.8 0.0 7.8e-32 109.6 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CCD24199.1 - 4.9e-15 55.1 0.1 1.8e-14 53.3 0.1 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CCD24199.1 - 4.7e-13 49.1 0.0 1.1e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CCD24199.1 - 1.7e-06 27.7 0.0 3.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CCD24199.1 - 2.8e-05 24.2 0.0 5.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 CCD24199.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 CCD24199.1 - 0.18 11.3 0.0 0.43 10.0 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain FTR1 PF03239.14 CCD24200.1 - 2.8e-100 335.4 3.7 3.3e-100 335.2 3.7 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Amidase_5 PF05382.13 CCD24200.1 - 0.0047 16.8 0.3 0.0098 15.8 0.3 1.4 1 0 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase S_2TMBeta PF18153.1 CCD24200.1 - 0.022 14.5 0.4 0.063 13.1 0.4 1.7 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain DUF4229 PF14012.6 CCD24200.1 - 0.73 10.0 2.7 2.4 8.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) Glyco_transf_15 PF01793.16 CCD24201.1 - 2.6e-118 395.0 12.1 3.6e-118 394.5 12.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Abhydrolase_1 PF00561.20 CCD24202.1 - 3.7e-22 79.2 0.0 4.7e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCD24202.1 - 3.7e-18 67.0 0.0 4.4e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCD24202.1 - 2.6e-15 56.4 0.0 1.5e-14 53.9 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 CCD24202.1 - 1.2e-07 31.6 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 CCD24202.1 - 4.3e-05 23.3 0.0 0.00039 20.2 0.0 2.3 3 0 0 3 3 3 1 PGAP1-like protein Esterase PF00756.20 CCD24202.1 - 0.0013 18.4 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 CCD24202.1 - 0.0014 18.7 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 CCD24202.1 - 0.0021 17.9 0.0 0.014 15.2 0.0 2.3 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 CCD24202.1 - 0.0023 17.8 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Chlorophyllase2 PF12740.7 CCD24202.1 - 0.017 14.1 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 CCD24202.1 - 0.094 12.6 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) F-box-like PF12937.7 CCD24203.1 - 0.00027 20.7 0.0 0.00057 19.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CCD24203.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 F-box domain MCM PF00493.23 CCD24204.1 - 7.7e-103 342.4 0.0 1.2e-102 341.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCD24204.1 - 3.6e-30 104.4 0.3 6.3e-30 103.6 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCD24204.1 - 4e-21 75.2 1.0 1e-20 73.9 1.0 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CCD24204.1 - 8.3e-17 61.7 2.1 8.3e-17 61.7 2.1 2.1 2 0 0 2 2 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CCD24204.1 - 1.5e-07 31.0 0.0 1.7e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CCD24204.1 - 7.9e-07 29.1 0.0 9.9e-06 25.6 0.0 2.8 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 CCD24204.1 - 0.00047 20.7 1.6 0.00095 19.8 0.1 2.2 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI C-terminal AAA_lid_2 PF17863.1 CCD24204.1 - 0.0084 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 CCD24204.1 - 0.061 13.2 0.0 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCD24204.1 - 0.079 12.7 0.0 0.7 9.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 CCD24204.1 - 0.15 12.4 0.2 3.9 7.8 0.0 2.9 1 1 0 2 2 2 0 AAA ATPase domain DER1 PF04511.15 CCD24205.1 - 3.6e-41 141.2 12.1 4.1e-41 141.0 12.1 1.0 1 0 0 1 1 1 1 Der1-like family Antimicrobial12 PF08107.11 CCD24205.1 - 0.042 13.6 0.4 0.085 12.6 0.4 1.4 1 0 0 1 1 1 0 Pleurocidin family SH3_1 PF00018.28 CCD24206.1 - 4.1e-25 87.1 0.0 2.5e-13 49.4 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CCD24206.1 - 3.6e-15 55.6 0.1 5.3e-11 42.2 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 CCD24206.1 - 6.1e-15 55.2 0.1 2e-14 53.5 0.0 1.9 2 0 0 2 2 2 1 PX domain SH3_2 PF07653.17 CCD24206.1 - 5.4e-10 38.8 0.0 3.3e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain PB1 PF00564.24 CCD24206.1 - 0.0018 18.2 0.1 0.0044 16.9 0.1 1.7 1 0 0 1 1 1 1 PB1 domain ARD PF03079.14 CCD24206.1 - 2.1 8.5 5.0 0.64 10.2 0.4 2.5 3 1 0 3 3 3 0 ARD/ARD' family Glyco_transf_15 PF01793.16 CCD24207.1 - 6.6e-107 357.5 13.5 8.7e-107 357.1 13.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.32 CCD24208.1 - 4.2e-49 163.5 21.2 1.7e-09 38.1 0.4 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 CCD24208.1 - 3.8e-40 137.1 2.2 6.7e-40 136.3 2.2 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 CCD24208.1 - 3.6e-12 46.4 0.1 0.81 10.0 0.0 6.2 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCD24208.1 - 4.2e-06 26.3 0.0 0.34 10.2 0.0 3.5 3 0 0 3 3 3 2 WD40-like domain LisH PF08513.11 CCD24208.1 - 7.9e-06 25.6 1.4 1e-05 25.3 0.1 2.0 2 0 0 2 2 2 1 LisH Nup160 PF11715.8 CCD24208.1 - 6e-05 21.9 2.0 0.072 11.7 0.1 3.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CCD24208.1 - 0.00039 19.5 0.0 0.51 9.2 0.0 3.8 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 CCD24208.1 - 0.017 15.0 0.0 8.1 6.4 0.0 3.5 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat Cytochrom_D1 PF02239.16 CCD24208.1 - 0.022 13.3 0.2 0.17 10.4 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 CCD24208.1 - 0.07 13.1 0.1 18 5.4 0.0 3.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 CCD24208.1 - 0.081 11.2 0.0 0.67 8.2 0.0 2.0 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz SPX PF03105.19 CCD24208.1 - 6.4 6.6 25.5 3.7 7.4 9.0 2.3 2 0 0 2 2 2 0 SPX domain PGI PF00342.19 CCD24209.1 - 3.7e-249 827.3 5.3 4.2e-249 827.1 5.3 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase SAP30_Sin3_bdg PF13867.6 CCD24209.1 - 0.13 12.6 0.2 13 6.2 0.1 2.8 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 CAF1C_H4-bd PF12265.8 CCD24210.1 - 1.2e-18 67.1 2.3 2.9e-18 65.9 0.8 2.4 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CCD24210.1 - 1.4e-14 54.2 9.3 0.012 16.4 1.6 6.6 6 1 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.11 CCD24210.1 - 1.9e-08 34.4 3.4 2.6e-06 27.4 0.3 3.5 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CCD24210.1 - 3.7e-07 30.3 4.3 0.086 13.1 0.0 5.5 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain SdiA-regulated PF06977.11 CCD24210.1 - 0.11 11.7 0.0 3.3 6.8 0.0 2.3 1 1 1 2 2 2 0 SdiA-regulated NpwBP PF12622.7 CCD24211.1 - 8.6e-10 39.2 1.8 9.1e-10 39.2 0.7 1.6 2 0 0 2 2 2 1 mRNA biogenesis factor Med8 PF10232.9 CCD24212.1 - 7.4e-17 61.7 3.3 9.8e-17 61.3 3.3 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 NPV_P10 PF05531.12 CCD24212.1 - 0.0066 16.9 3.8 0.89 10.1 0.1 3.3 2 2 1 3 3 3 2 Nucleopolyhedrovirus P10 protein Mito_carr PF00153.27 CCD24213.1 - 1.4e-74 246.1 4.3 1.1e-27 95.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 CCD24213.1 - 0.017 15.4 0.0 1.8 8.9 0.0 3.0 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Hydantoinase_B PF02538.14 CCD24213.1 - 0.037 12.4 0.0 0.14 10.6 0.0 1.7 2 0 0 2 2 2 0 Hydantoinase B/oxoprolinase Ribosomal_L21e PF01157.18 CCD24214.1 - 4.1e-42 142.1 3.9 1.9e-41 140.0 2.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.9 CCD24214.1 - 0.00022 20.9 0.1 0.00027 20.6 0.1 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 S4 PF01479.25 CCD24215.1 - 1.6e-13 50.1 0.2 6.3e-13 48.2 0.2 2.0 1 0 0 1 1 1 1 S4 domain cwf18 PF08315.12 CCD24216.1 - 1.2e-07 32.4 11.5 1.6e-07 32.1 11.5 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor UPF0016 PF01169.19 CCD24217.1 - 6.9e-40 135.2 19.1 2.7e-20 72.5 3.5 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Presenilin PF01080.17 CCD24217.1 - 0.17 10.6 7.9 0.01 14.6 1.5 2.0 2 0 0 2 2 2 0 Presenilin tRNA_int_end_N2 PF12928.7 CCD24218.1 - 2.5e-14 53.2 0.0 4.9e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Med30 PF11315.8 CCD24218.1 - 0.1 12.8 0.3 0.63 10.2 0.1 2.3 2 0 0 2 2 2 0 Mediator complex subunit 30 BRO1 PF03097.18 CCD24219.1 - 7.6e-92 308.1 7.5 7.6e-92 308.1 7.5 1.5 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CCD24219.1 - 1.9e-21 76.6 12.0 4.4e-21 75.5 12.0 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Phage_Mu_Gam PF07352.12 CCD24219.1 - 0.41 10.5 9.0 0.32 10.9 6.6 2.1 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein MBA1 PF07961.11 CCD24220.1 - 2.6e-92 308.2 2.1 3.1e-92 307.9 2.1 1.0 1 0 0 1 1 1 1 MBA1-like protein Glyco_transf_20 PF00982.21 CCD24220.1 - 0.031 12.9 0.2 0.044 12.5 0.2 1.3 1 1 0 1 1 1 0 Glycosyltransferase family 20 Tim44 PF04280.15 CCD24220.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Tim44-like domain Ribosomal_L19 PF01245.20 CCD24221.1 - 0.028 14.3 0.1 0.081 12.9 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein L19 Radical_SAM_C PF16199.5 CCD24222.1 - 2.1e-32 111.0 0.0 4e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CCD24222.1 - 2.7e-17 63.7 0.4 1.3e-16 61.4 0.0 2.2 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CCD24222.1 - 1.5e-10 41.4 0.1 2.7e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCD24222.1 - 1.5e-06 28.1 0.0 3.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCD24222.1 - 0.013 15.9 0.1 0.027 14.9 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HTH_28 PF13518.6 CCD24222.1 - 0.16 12.2 0.1 0.62 10.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Ceramidase PF05875.12 CCD24223.1 - 3.4e-86 288.9 16.1 4.1e-86 288.7 16.1 1.0 1 0 0 1 1 1 1 Ceramidase DUF2892 PF11127.8 CCD24223.1 - 3.1 7.9 5.7 0.93 9.6 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) SRF-TF PF00319.18 CCD24224.1 - 6e-21 73.7 0.0 1e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ribosomal_S6e PF01092.19 CCD24225.1 - 5e-22 78.2 0.1 1.2e-21 76.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S6e MFS_1 PF07690.16 CCD24226.1 - 1.4e-48 165.6 25.3 1.4e-48 165.6 25.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCD24226.1 - 7.3e-20 71.2 6.3 7.3e-20 71.2 6.3 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 CCD24226.1 - 0.00061 19.2 5.9 0.00061 19.2 5.9 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TauE PF01925.19 CCD24226.1 - 0.23 11.1 0.0 0.23 11.1 0.0 4.3 3 2 1 4 4 4 0 Sulfite exporter TauE/SafE NOG1_N PF17835.1 CCD24227.1 - 6.9e-49 165.9 0.1 6.9e-49 165.9 0.1 2.7 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOGCT PF08155.11 CCD24227.1 - 8.4e-27 92.9 1.7 2.3e-26 91.5 1.7 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 CCD24227.1 - 5.9e-26 90.0 0.3 1.8e-25 88.5 0.3 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 CCD24227.1 - 1.9e-16 60.2 0.0 6.1e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCD24227.1 - 1e-07 31.6 0.0 2.3e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CCD24227.1 - 0.0002 21.3 0.3 0.18 11.7 0.1 3.5 4 0 0 4 4 4 1 RsgA GTPase Gtr1_RagA PF04670.12 CCD24227.1 - 0.00093 18.6 0.0 0.0026 17.1 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 CCD24227.1 - 0.01 15.9 0.1 3 7.9 0.0 3.2 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.6 CCD24227.1 - 0.013 15.9 0.0 0.3 11.4 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 CCD24227.1 - 0.088 13.0 0.0 0.46 10.7 0.0 2.3 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 CCD24227.1 - 0.27 11.3 1.6 1.7 8.7 0.1 2.7 3 0 0 3 3 3 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 CCD24228.1 - 2.2e-17 63.6 0.4 2.2e-17 63.6 0.4 2.6 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 CCD24228.1 - 8.8e-10 38.7 0.1 5e-09 36.2 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCD24228.1 - 5.5e-09 35.8 0.3 9.2e-06 25.3 0.1 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CCD24228.1 - 0.045 13.5 0.4 7 6.4 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF2730 PF10805.8 CCD24228.1 - 0.046 13.8 2.4 0.31 11.1 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) cobW PF02492.19 CCD24228.1 - 0.057 13.0 0.2 0.38 10.3 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Hexapep PF00132.24 CCD24229.1 - 6.5e-14 51.0 12.9 9e-09 34.7 1.9 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CCD24229.1 - 9.9e-13 47.6 15.1 2.1e-09 37.0 0.5 3.1 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Abhydrolase_1 PF00561.20 CCD24230.1 - 1.5e-27 96.9 0.0 3.6e-27 95.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCD24230.1 - 3.4e-12 46.1 0.0 1.7e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCD24230.1 - 1.8e-05 25.5 0.0 3.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family ORC3_N PF07034.11 CCD24230.1 - 0.0095 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Cutinase PF01083.22 CCD24230.1 - 0.014 15.4 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase PIG-Y PF15159.6 CCD24231.1 - 0.0098 16.8 10.4 0.018 15.9 10.4 1.4 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y CoA_binding_3 PF13727.6 CCD24231.1 - 0.11 12.5 1.2 0.13 12.3 1.2 1.0 1 0 0 1 1 1 0 CoA-binding domain tRNA-synt_1b PF00579.25 CCD24232.1 - 3.4e-75 253.1 0.0 5.3e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF1542 PF07564.11 CCD24232.1 - 0.2 11.8 1.8 0.26 11.4 0.3 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Romo1 PF10247.9 CCD24233.1 - 3.5e-27 94.6 10.2 4.5e-27 94.2 10.2 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 PAXNEB PF05625.11 CCD24234.1 - 1.1e-92 311.0 0.4 1.4e-92 310.7 0.4 1.1 1 0 0 1 1 1 1 PAXNEB protein Pantoate_transf PF02548.15 CCD24235.1 - 2.8e-90 302.2 0.0 3.3e-90 302.0 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 CCD24235.1 - 0.002 17.7 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Asp_Glu_race PF01177.22 CCD24235.1 - 0.021 14.7 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase WD40 PF00400.32 CCD24236.1 - 1.7e-24 85.6 10.9 9e-06 26.3 0.0 6.1 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD24236.1 - 1e-15 57.8 0.1 1.1e-05 25.6 0.0 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CCD24236.1 - 0.0001 21.5 0.0 0.00027 20.1 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region Ge1_WD40 PF16529.5 CCD24236.1 - 0.0016 17.5 0.2 12 4.7 0.0 3.9 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CCD24236.1 - 0.0019 18.1 0.0 0.44 10.4 0.0 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CCD24236.1 - 0.0023 16.7 0.2 0.26 9.9 0.1 2.8 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 CCD24236.1 - 0.0084 14.7 0.0 1.1 7.7 0.0 2.1 1 1 1 2 2 2 2 Cytochrome D1 heme domain Frtz PF11768.8 CCD24236.1 - 0.02 13.2 0.1 0.16 10.2 0.0 2.1 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 CCD24236.1 - 0.088 12.8 0.0 43 4.2 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 CCD24236.1 - 0.14 11.5 0.6 0.54 9.5 0.2 2.0 2 0 0 2 2 2 0 WD40-like domain Hira PF07569.11 CCD24236.1 - 0.58 9.8 1.9 6.2 6.5 0.1 3.1 4 1 1 5 5 5 0 TUP1-like enhancer of split UMP1 PF05348.11 CCD24237.1 - 6.4e-40 136.1 0.2 7.5e-40 135.8 0.2 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 GYF PF02213.16 CCD24238.1 - 1.3e-16 59.9 0.0 2.9e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 GYF domain Sec66 PF09802.9 CCD24239.1 - 1.6e-67 226.6 1.4 2.1e-67 226.2 1.4 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Tubulin_3 PF14881.6 CCD24239.1 - 0.053 13.2 0.1 1.3 8.7 0.0 2.3 1 1 0 2 2 2 0 Tubulin domain Endonuc-FokI_C PF09254.11 CCD24239.1 - 0.053 12.8 0.2 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease FokI, C terminal DUF3015 PF11220.8 CCD24239.1 - 0.26 11.2 3.5 6.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) NPL4 PF05021.15 CCD24240.1 - 5.2e-140 466.1 0.2 6.7e-140 465.8 0.2 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 CCD24240.1 - 1.7e-69 232.6 1.5 2.6e-69 231.9 1.5 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 CCD24240.1 - 0.0021 18.5 0.0 0.016 15.7 0.0 2.4 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 HSP70 PF00012.20 CCD24241.1 - 4.3e-176 586.6 10.6 4.3e-176 586.6 10.6 2.0 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CCD24241.1 - 5.4e-07 28.7 0.1 1e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 CCD24241.1 - 0.073 12.8 0.4 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain NLE PF08154.12 CCD24241.1 - 0.12 12.9 0.1 0.44 11.1 0.0 2.0 2 0 0 2 2 2 0 NLE (NUC135) domain FtsA PF14450.6 CCD24241.1 - 0.16 12.4 9.6 1 9.8 0.1 4.3 4 2 0 4 4 4 0 Cell division protein FtsA Pex24p PF06398.11 CCD24242.1 - 1.9e-35 122.5 23.4 2.7e-35 122.0 23.4 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Rpp20 PF12328.8 CCD24243.1 - 4.9e-26 91.3 9.9 3.4e-18 65.9 4.0 2.1 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 CCD24243.1 - 2.5e-10 40.0 0.4 4.2e-10 39.3 0.4 1.3 1 0 0 1 1 1 1 Alba PNPase PF03726.14 CCD24243.1 - 0.04 14.4 2.7 0.087 13.3 1.8 2.0 1 1 1 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain MSC PF09402.10 CCD24243.1 - 0.042 13.3 0.4 0.049 13.1 0.4 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Baculo_E56 PF04639.12 CCD24243.1 - 0.097 11.9 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope PDH PF02153.17 CCD24244.1 - 8.7e-08 31.5 0.2 1.4e-07 30.8 0.2 1.4 1 1 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 CCD24244.1 - 9.3e-05 22.9 0.0 0.00022 21.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 CCD24244.1 - 0.00013 21.7 0.0 0.00034 20.3 0.0 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 CCD24244.1 - 0.00035 20.8 0.0 0.00061 20.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 CCD24244.1 - 0.0043 16.4 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CCD24244.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CCD24244.1 - 0.023 14.3 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 CCD24244.1 - 0.08 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Fungal_TACC PF12709.7 CCD24247.1 - 1.5e-32 111.8 12.4 1.5e-32 111.8 12.4 10.9 5 1 6 12 12 12 1 Fungal Transforming acidic coiled-coil (TACC) proteins SHE3 PF17078.5 CCD24247.1 - 6.1e-05 22.8 26.0 6.1e-05 22.8 26.0 6.8 2 1 5 7 7 7 1 SWI5-dependent HO expression protein 3 GAS PF13851.6 CCD24247.1 - 0.33 10.3 117.5 0.014 14.8 16.3 7.6 2 1 4 6 6 6 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 CCD24247.1 - 1.4 7.8 112.0 0.011 14.7 24.5 6.0 2 1 4 6 6 6 0 Spc7 kinetochore protein Asp_protease PF09668.10 CCD24248.1 - 5.2e-50 168.4 0.0 8e-50 167.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CCD24248.1 - 3.2e-18 66.1 0.0 7e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CCD24248.1 - 4.7e-10 40.0 0.4 5.7e-09 36.5 0.1 2.3 2 0 0 2 2 2 1 Aspartyl protease UBA PF00627.31 CCD24248.1 - 9.4e-08 31.8 0.0 2.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.20 CCD24248.1 - 0.0047 17.2 0.1 0.024 14.9 0.0 2.3 2 1 0 2 2 2 1 Retroviral aspartyl protease RVP_2 PF08284.11 CCD24248.1 - 0.0075 16.0 0.0 0.036 13.8 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease UN_NPL4 PF11543.8 CCD24248.1 - 0.036 14.6 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 SOG2 PF10428.9 CCD24248.1 - 0.72 9.0 4.4 1.6 7.8 4.6 1.4 2 0 0 2 2 2 0 RAM signalling pathway protein UCH PF00443.29 CCD24249.1 - 2.4e-56 191.1 1.4 5.2e-56 190.0 1.4 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCD24249.1 - 8.7e-23 81.4 5.6 2e-22 80.2 5.6 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 CCD24249.1 - 6.2e-06 26.7 0.0 2.4e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Cys_rich_KTR PF14205.6 CCD24249.1 - 0.029 14.1 0.5 0.082 12.7 0.5 1.7 1 0 0 1 1 1 0 Cysteine-rich KTR MazG_C PF18722.1 CCD24249.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 MazG C-terminal domain NOB1_Zn_bind PF08772.11 CCD24249.1 - 0.11 12.7 2.5 0.4 10.9 2.5 1.9 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DUF3837 PF12939.7 CCD24249.1 - 0.13 12.7 0.3 11 6.5 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3837) FTR1 PF03239.14 CCD24250.1 - 3.9e-98 328.4 6.4 4.6e-98 328.2 6.4 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Rft-1 PF04506.13 CCD24250.1 - 0.0047 15.8 0.1 0.0095 14.7 0.0 1.4 1 1 0 1 1 1 1 Rft protein B12D PF06522.11 CCD24250.1 - 0.72 9.7 2.2 0.79 9.6 0.2 2.1 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit adh_short PF00106.25 CCD24251.1 - 8e-17 61.3 0.0 4.3e-14 52.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 CCD24251.1 - 9.9e-09 35.3 0.1 3.2e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CCD24251.1 - 1.7e-05 24.4 0.0 2.3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CCD24251.1 - 0.029 13.8 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Suv3_N PF18114.1 CCD24252.1 - 0.059 13.5 0.4 0.47 10.6 0.0 2.4 2 0 0 2 2 2 0 Suv3 helical N-terminal domain Metallophos PF00149.28 CCD24253.1 - 7.5e-38 131.1 0.1 9.3e-38 130.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CCD24253.1 - 0.015 15.5 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain 8TM_micro PF17028.5 CCD24253.1 - 0.1 12.3 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain UCH PF00443.29 CCD24254.1 - 2.4e-49 168.1 1.5 2.4e-49 168.1 1.5 3.2 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Aminotran_1_2 PF00155.21 CCD24255.1 - 9.3e-16 57.9 0.0 4.6e-15 55.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CCD24255.1 - 0.0022 16.8 0.0 0.0048 15.7 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase PET122 PF05476.11 CCD24256.1 - 3.1e-87 292.2 4.8 3.5e-87 292.0 4.8 1.0 1 0 0 1 1 1 1 PET122 60KD_IMP PF02096.20 CCD24257.1 - 2.8e-21 76.1 1.6 2.8e-21 76.1 1.6 2.0 2 0 0 2 2 2 1 60Kd inner membrane protein RhoGAP PF00620.27 CCD24258.1 - 2e-37 128.3 0.8 5.2e-37 127.0 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain RasGEF_N PF00618.20 CCD24258.1 - 4.1e-17 62.3 0.6 4.1e-17 62.3 0.6 4.6 4 0 0 4 4 4 1 RasGEF N-terminal motif RasGEF PF00617.19 CCD24258.1 - 1.2e-10 41.9 0.3 1.8e-07 31.5 0.0 3.9 2 1 0 2 2 2 2 RasGEF domain UPF0160 PF03690.13 CCD24259.1 - 1.4e-127 425.7 0.0 1.6e-127 425.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Gallidermin PF02052.15 CCD24259.1 - 0.0073 16.6 0.0 0.031 14.6 0.0 2.0 2 0 0 2 2 2 1 Gallidermin Sec34 PF04136.15 CCD24260.1 - 6.8e-41 139.6 10.8 6.8e-41 139.6 10.8 3.1 4 0 0 4 4 4 1 Sec34-like family CBFD_NFYB_HMF PF00808.23 CCD24263.1 - 2e-12 47.2 0.0 3.8e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1978 PF09321.10 CCD24263.1 - 0.032 13.5 0.2 0.041 13.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) SPT2 PF08243.11 CCD24264.1 - 0.015 15.8 10.6 0.015 15.8 10.6 2.3 2 1 1 3 3 3 0 SPT2 chromatin protein PBP1_TM PF14812.6 CCD24264.1 - 0.016 15.6 11.6 0.016 15.6 11.6 2.8 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DASH_Spc19 PF08287.11 CCD24264.1 - 3.8 7.4 20.1 1.2 9.0 3.5 2.8 2 1 1 3 3 3 0 Spc19 Rad4 PF03835.15 CCD24265.1 - 3.1e-34 117.8 4.7 8.1e-34 116.4 4.7 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 CCD24265.1 - 1.7e-26 92.4 0.2 3.6e-26 91.4 0.2 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CCD24265.1 - 2.5e-16 59.2 0.1 6.9e-16 57.8 0.1 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CCD24265.1 - 0.00011 23.0 0.0 0.00011 23.0 0.0 3.8 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 CCD24265.1 - 0.0012 19.2 0.6 0.0055 17.1 0.0 2.3 3 0 0 3 3 3 1 Transglutaminase-like superfamily ChaC PF04752.12 CCD24266.1 - 9.8e-62 208.2 0.0 1.2e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein HECT_2 PF09814.9 CCD24266.1 - 0.068 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Gag_spuma PF03276.14 CCD24266.1 - 0.12 10.8 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Copper-fist PF00649.18 CCD24267.1 - 2.1e-19 68.7 3.7 5.1e-19 67.5 3.7 1.7 1 0 0 1 1 1 1 Copper fist DNA binding domain SNF2_N PF00176.23 CCD24268.1 - 1.3e-63 214.8 0.1 2.4e-63 214.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cdh1_DBD_1 PF18196.1 CCD24268.1 - 4.7e-38 130.2 2.7 4.7e-38 130.2 2.7 3.9 3 0 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 DUF4208 PF13907.6 CCD24268.1 - 9.5e-28 96.5 2.6 9.5e-28 96.5 2.6 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Chromo PF00385.24 CCD24268.1 - 4.2e-25 87.4 2.9 5.6e-15 55.0 0.1 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 CCD24268.1 - 4.9e-20 71.9 0.1 2e-19 69.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD24268.1 - 6.5e-09 36.0 0.4 1.6e-07 31.5 0.0 3.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 CCD24268.1 - 0.0025 17.9 0.0 0.011 16.0 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 CCD24268.1 - 0.0052 16.8 0.0 0.0052 16.8 0.0 3.6 3 0 0 3 3 3 1 SLIDE Myb_DNA-bind_6 PF13921.6 CCD24268.1 - 0.0053 17.0 0.0 0.024 14.9 0.0 2.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain CHDCT2 PF08074.11 CCD24268.1 - 0.02 15.0 0.0 0.02 15.0 0.0 2.7 4 0 0 4 4 4 0 CHDCT2 (NUC038) domain RRM_1 PF00076.22 CCD24269.1 - 3.8e-86 282.9 7.2 2.8e-21 75.1 0.2 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CCD24269.1 - 6.1e-18 64.8 1.1 5.1e-17 61.8 0.0 2.7 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 CCD24269.1 - 2.3e-13 49.8 0.7 0.05 13.2 0.0 4.7 2 1 3 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CCD24269.1 - 7.9e-07 29.1 10.1 0.51 10.4 1.5 5.1 5 0 0 5 5 5 3 RNA binding motif RRM_7 PF16367.5 CCD24269.1 - 1.8e-06 28.0 1.0 0.045 13.9 0.0 5.1 4 3 0 4 4 4 1 RNA recognition motif RRM_occluded PF16842.5 CCD24269.1 - 1.2e-05 25.1 0.0 0.082 12.8 0.0 4.1 4 0 0 4 4 4 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CCD24269.1 - 0.0045 17.0 1.1 13 5.8 0.0 3.8 4 0 0 4 4 3 1 Nup53/35/40-type RNA recognition motif YflT PF11181.8 CCD24269.1 - 0.0066 16.9 7.9 0.27 11.8 0.7 3.4 3 0 0 3 3 3 1 Heat induced stress protein YflT ACT PF01842.25 CCD24269.1 - 0.02 14.7 0.0 13 5.7 0.0 3.3 3 0 0 3 3 3 0 ACT domain Bac_DNA_binding PF00216.21 CCD24269.1 - 0.026 14.7 3.2 2.8 8.2 0.3 3.4 3 0 0 3 3 3 0 Bacterial DNA-binding protein OB_RNB PF08206.11 CCD24269.1 - 0.065 12.9 5.2 8.4 6.2 0.2 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain SAPIS-gp6 PF16722.5 CCD24269.1 - 6.2 7.3 8.3 2.9 8.3 1.0 2.9 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus PhoLip_ATPase_C PF16212.5 CCD24270.1 - 8.8e-78 261.5 28.2 8.8e-78 261.5 28.2 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCD24270.1 - 7.5e-19 67.2 1.5 2.2e-18 65.7 1.5 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CCD24270.1 - 1.2e-11 44.6 0.0 5.4e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CCD24270.1 - 4.7e-09 36.8 0.5 0.00029 21.2 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CCD24270.1 - 5.2e-05 22.8 0.0 5.2e-05 22.8 0.0 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CCD24270.1 - 0.0033 17.2 0.2 0.0071 16.1 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4131 PF13567.6 CCD24270.1 - 0.025 14.2 4.7 5.1 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) NESP55 PF06390.12 CCD24271.1 - 0.45 10.1 8.4 0.023 14.3 2.6 1.8 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Rad21_Rec8_N PF04825.13 CCD24272.1 - 4.1e-16 59.1 0.8 1.4e-15 57.4 0.8 1.9 1 1 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CCD24272.1 - 0.047 13.0 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein PGA2 PF07543.12 CCD24272.1 - 4.4 7.3 10.6 2.2 8.2 7.3 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 ICL PF00463.21 CCD24273.1 - 3e-159 530.9 0.0 3.4e-159 530.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CCD24273.1 - 2.3e-06 27.2 0.0 3.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase EcoEI_R_C PF08463.10 CCD24273.1 - 0.024 14.7 0.1 1 9.4 0.1 2.5 2 0 0 2 2 2 0 EcoEI R protein C-terminal Clat_adaptor_s PF01217.20 CCD24274.1 - 3.6e-11 43.2 0.1 1.2e-10 41.5 0.1 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_S20p PF01649.18 CCD24274.1 - 0.11 13.1 0.0 0.22 12.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S20 Bromo_TP PF07524.13 CCD24275.1 - 6.1e-06 26.2 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated CENP-B_dimeris PF09026.10 CCD24275.1 - 0.3 11.5 6.3 0.96 9.9 6.3 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NUC173 PF08161.12 CCD24276.1 - 3.8e-73 245.5 1.9 5.8e-70 235.1 0.3 3.9 4 0 0 4 4 4 2 NUC173 domain HEAT PF02985.22 CCD24276.1 - 3.4e-05 23.7 0.2 0.041 14.2 0.0 5.0 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 CCD24276.1 - 0.17 12.3 0.4 6.2 7.3 0.0 3.7 5 0 0 5 5 5 0 HEAT repeats RTP1_C1 PF10363.9 CCD24276.1 - 0.46 10.7 7.3 23 5.2 0.1 4.8 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Ribosomal_S16 PF00886.19 CCD24277.1 - 5.9e-25 87.1 0.1 8.2e-25 86.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 DEAD_2 PF06733.15 CCD24279.1 - 1.9e-50 170.9 0.0 3.6e-50 170.0 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 CCD24279.1 - 5.2e-47 160.2 0.0 1e-46 159.2 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 CCD24279.1 - 8e-05 22.7 4.6 0.034 14.2 0.2 3.0 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CCD24279.1 - 0.00069 19.4 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase PhoH PF02562.16 CCD24279.1 - 0.0035 16.8 0.2 0.25 10.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein DUF4611 PF15387.6 CCD24279.1 - 0.015 15.5 0.8 0.2 11.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AAA_22 PF13401.6 CCD24279.1 - 0.022 15.0 0.0 3.7 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain zf-TFIIIC PF12660.7 CCD24280.1 - 2.9e-10 40.0 0.1 5.9e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex ANAPC4_WD40 PF12894.7 CCD24280.1 - 0.0004 20.6 0.1 1.3 9.4 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain NPC1_N PF16414.5 CCD24281.1 - 1.2e-80 270.6 11.8 2.2e-80 269.7 11.8 1.4 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 CCD24281.1 - 5e-48 163.8 33.4 7.2e-47 160.0 30.2 3.5 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CCD24281.1 - 1.7e-37 128.6 6.4 1.7e-37 128.6 6.4 2.8 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CCD24281.1 - 0.0053 15.7 1.3 0.0053 15.7 1.3 2.2 2 0 0 2 2 2 2 MMPL family ACR_tran PF00873.19 CCD24281.1 - 0.023 12.4 25.7 0.042 11.5 19.8 2.5 3 0 0 3 3 3 0 AcrB/AcrD/AcrF family Mpv17_PMP22 PF04117.12 CCD24282.1 - 3.1e-25 88.2 3.7 3.1e-25 88.2 3.7 1.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family PPR_2 PF13041.6 CCD24283.1 - 0.00042 20.5 3.0 0.13 12.4 0.1 3.5 4 0 0 4 4 4 2 PPR repeat family CagY_M PF07337.11 CCD24283.1 - 0.033 13.8 0.0 0.1 12.2 0.0 1.9 1 0 0 1 1 1 0 DC-EC Repeat PPR_3 PF13812.6 CCD24283.1 - 0.059 13.5 3.7 0.2 11.8 0.1 3.6 3 1 1 4 4 4 0 Pentatricopeptide repeat domain Pil1 PF13805.6 CCD24284.1 - 1.7e-123 411.3 0.5 2.3e-123 410.9 0.5 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 PCP_red PF08369.10 CCD24284.1 - 0.021 15.0 0.6 0.17 12.1 0.3 2.5 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit zf-C2H2 PF00096.26 CCD24285.1 - 6e-07 29.6 15.4 0.00012 22.3 1.8 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCD24285.1 - 0.00066 20.0 0.3 0.00066 20.0 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCD24285.1 - 0.0011 19.6 10.0 0.027 15.3 1.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CCD24285.1 - 0.8 10.2 4.4 3.1 8.3 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 CCD24285.1 - 1.6 8.5 6.5 2.3 8.1 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Ribosomal_L35p PF01632.19 CCD24285.1 - 8.4 7.0 7.4 0.94 10.0 1.0 2.5 2 1 0 2 2 2 0 Ribosomal protein L35 Peptidase_C48 PF02902.19 CCD24286.1 - 3.5e-40 138.2 1.3 3.5e-40 138.2 1.3 2.2 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Tra_M PF05261.11 CCD24286.1 - 0.15 12.1 4.6 8.6 6.4 0.2 2.7 2 0 0 2 2 2 0 TraM protein, DNA-binding UPF0227 PF05728.12 CCD24286.1 - 1.8 8.4 5.0 1.7 8.5 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) SIR2 PF02146.17 CCD24287.1 - 2e-52 177.7 0.0 3.1e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Sir2 family HSDR_N PF04313.14 CCD24287.1 - 0.24 11.3 2.2 0.39 10.6 2.2 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) FYVE_2 PF02318.16 CCD24287.1 - 2.9 8.1 5.5 1.3 9.2 0.1 2.4 2 1 1 3 3 3 0 FYVE-type zinc finger DEAD PF00270.29 CCD24289.1 - 6.3e-41 140.1 0.1 1.6e-40 138.7 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD24289.1 - 5.5e-24 84.6 0.0 9.7e-23 80.6 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CCD24289.1 - 7.4e-16 58.1 0.4 1.6e-15 57.1 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CCD24289.1 - 7.3e-08 32.6 1.9 9.2e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CCD24289.1 - 0.007 15.6 0.0 0.007 15.6 0.0 2.3 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 CCD24289.1 - 0.086 13.1 0.1 0.49 10.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain DUF4498 PF14926.6 CCD24290.1 - 0.0014 18.0 0.2 0.0019 17.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) DUF2207 PF09972.9 CCD24290.1 - 0.004 16.0 0.2 0.0047 15.8 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) RB_A PF01858.17 CCD24290.1 - 0.027 14.3 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain PHM7_cyt PF14703.6 CCD24290.1 - 0.03 14.6 0.3 0.036 14.3 0.3 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF2781 PF10914.8 CCD24295.1 - 5.8e-38 130.6 6.9 7.1e-38 130.3 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DAO PF01266.24 CCD24296.1 - 2.2e-15 57.1 0.1 1.8e-14 54.1 0.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 CCD24296.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SH3_6 PF12913.7 CCD24296.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 SH3 domain (SH3b1 type) UDPG_MGDP_dh_N PF03721.14 CCD24296.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain WW PF00397.26 CCD24297.1 - 9e-11 41.7 1.0 2.3e-10 40.3 1.0 1.8 1 0 0 1 1 1 1 WW domain CYSTM PF12734.7 CCD24297.1 - 0.019 15.3 4.1 0.019 15.3 4.1 4.3 3 1 0 3 3 3 0 Cysteine-rich TM module stress tolerance DUF2076 PF09849.9 CCD24297.1 - 0.045 13.8 31.6 0.37 10.8 31.6 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PAT1 PF09770.9 CCD24297.1 - 1 7.5 5.9 1.1 7.4 5.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Microtub_bd PF16796.5 CCD24298.1 - 0.34 10.9 0.1 0.34 10.9 0.1 2.9 1 1 1 2 2 2 0 Microtubule binding APG6_N PF17675.1 CCD24298.1 - 5.6 7.5 14.8 0.75 10.3 10.7 1.6 2 0 0 2 2 2 0 Apg6 coiled-coil region Pyr_redox_2 PF07992.14 CCD24299.1 - 3.9e-66 223.3 5.2 4.4e-66 223.1 4.5 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CCD24299.1 - 6.6e-43 145.5 0.1 1.7e-42 144.1 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CCD24299.1 - 4.2e-20 72.1 5.3 3e-17 63.0 1.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CCD24299.1 - 7.6e-12 45.3 2.1 2.3e-09 37.2 0.1 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCD24299.1 - 2.4e-10 40.5 3.1 1.5e-05 25.1 0.8 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CCD24299.1 - 4.6e-09 35.8 5.8 7.3e-09 35.2 1.4 2.3 1 1 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CCD24299.1 - 5e-09 35.8 8.7 3.7e-06 26.4 0.7 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CCD24299.1 - 1.6e-06 27.5 1.2 1.6e-06 27.5 1.2 2.6 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.14 CCD24299.1 - 1e-05 24.5 11.3 0.00031 19.6 0.9 4.0 3 1 1 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 CCD24299.1 - 5.8e-05 22.5 1.1 0.19 11.0 0.3 2.6 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CCD24299.1 - 0.0003 20.1 6.2 0.023 13.9 0.4 3.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 CCD24299.1 - 0.00061 19.5 10.7 0.12 11.9 0.0 3.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 CCD24299.1 - 0.00089 18.6 1.0 0.0073 15.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 CCD24299.1 - 0.0017 17.6 0.4 2.3 7.3 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) THF_DHG_CYH_C PF02882.19 CCD24299.1 - 0.019 14.3 0.2 0.073 12.4 0.2 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4479 PF14794.6 CCD24299.1 - 0.8 9.6 3.8 18 5.3 0.2 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4479) 3HCDH_N PF02737.18 CCD24299.1 - 2.1 8.2 7.0 0.15 12.0 0.7 2.3 3 0 0 3 3 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fcf2 PF08698.11 CCD24300.1 - 3e-33 114.1 1.5 3e-33 114.1 1.5 2.5 2 1 1 3 3 3 1 Fcf2 pre-rRNA processing RED_C PF07807.11 CCD24300.1 - 0.62 10.5 9.6 0.047 14.2 4.2 2.0 2 0 0 2 2 2 0 RED-like protein C-terminal region WD40 PF00400.32 CCD24301.1 - 1.6e-05 25.5 2.2 4.9 8.2 0.0 5.9 7 0 0 7 7 7 2 WD domain, G-beta repeat FA_hydroxylase PF04116.13 CCD24302.1 - 1.2e-21 77.5 16.2 1.2e-21 77.5 16.2 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4306 PF14154.6 CCD24303.1 - 0.17 12.1 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Glyco_hydro_47 PF01532.20 CCD24304.1 - 4.3e-76 256.7 0.0 8.9e-76 255.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 CCD24304.1 - 0.13 11.8 0.0 3.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 RNase_T PF00929.24 CCD24305.1 - 1.5e-32 113.4 1.7 4.2e-32 112.0 0.6 2.1 2 0 0 2 2 2 1 Exonuclease DUF2026 PF09641.10 CCD24305.1 - 0.054 13.1 0.4 0.1 12.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2026) DUF4148 PF13663.6 CCD24305.1 - 0.12 12.6 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) TetR_C_23 PF17931.1 CCD24305.1 - 2.8 8.1 5.8 3.9 7.6 2.1 2.6 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_L22e PF01776.17 CCD24306.1 - 6.7e-39 132.6 0.5 8.1e-39 132.4 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family GFP PF01353.22 CCD24306.1 - 0.071 12.6 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Green fluorescent protein Methyltransf_34 PF11312.8 CCD24307.1 - 9.7e-94 314.0 0.5 1.1e-93 313.8 0.5 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Utp14 PF04615.13 CCD24307.1 - 0.0099 14.5 0.2 0.012 14.2 0.2 1.0 1 0 0 1 1 1 1 Utp14 protein Rsm22 PF09243.10 CCD24307.1 - 0.017 14.4 0.0 2.7 7.2 0.0 2.1 1 1 1 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 MecA PF05389.12 CCD24307.1 - 0.044 13.4 2.4 0.051 13.2 0.8 1.7 1 1 0 2 2 2 0 Negative regulator of genetic competence (MecA) Tubulin PF00091.25 CCD24308.1 - 1.8e-66 224.1 0.1 3.3e-66 223.2 0.1 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CCD24308.1 - 2.6e-42 144.0 0.2 2.2e-41 141.0 0.1 2.2 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CCD24308.1 - 0.00096 18.9 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 CCD24308.1 - 0.0086 16.4 0.0 0.026 14.9 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CCD24308.1 - 0.058 12.6 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Tubulin like PRESAN PF09687.10 CCD24308.1 - 5.4 7.6 9.7 2 9.0 5.5 2.3 3 0 0 3 3 3 0 Plasmodium RESA N-terminal UPF0121 PF03661.13 CCD24309.1 - 3.5e-13 49.5 15.9 5.6e-13 48.9 15.9 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TMEM208_SND2 PF05620.11 CCD24310.1 - 2e-45 154.6 0.1 2.3e-45 154.4 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 PPR_2 PF13041.6 CCD24311.1 - 2.5e-08 34.0 17.2 0.012 15.8 0.1 7.7 8 1 1 9 9 9 2 PPR repeat family PPR_long PF17177.4 CCD24311.1 - 1.8e-07 30.7 0.3 4.9e-05 22.8 0.1 2.9 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CCD24311.1 - 0.00023 21.2 15.1 2.1 8.8 0.1 6.8 8 0 0 8 8 8 3 PPR repeat TPR_14 PF13428.6 CCD24311.1 - 0.00044 20.8 0.5 11 7.2 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCD24311.1 - 0.00065 20.2 0.0 2.7 8.6 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat COX5A PF02284.16 CCD24311.1 - 0.0091 16.0 0.0 1.2 9.2 0.0 3.2 2 1 1 3 3 3 1 Cytochrome c oxidase subunit Va rRNA_processing PF08524.11 CCD24312.1 - 1.8e-34 118.9 39.2 2.1e-34 118.7 39.2 1.0 1 0 0 1 1 1 1 rRNA processing PV-1 PF06637.11 CCD24312.1 - 2.3 6.9 17.4 2.7 6.7 17.4 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Ntox16 PF15523.6 CCD24312.1 - 8 6.8 12.3 20 5.5 0.1 2.2 2 0 0 2 2 2 0 Novel toxin 16 GTP_EFTU PF00009.27 CCD24313.1 - 8.6e-63 211.4 0.1 1.5e-62 210.7 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CCD24313.1 - 1.6e-36 124.7 0.0 3.3e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 CCD24313.1 - 7.5e-31 106.1 0.0 1.7e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CCD24313.1 - 1.3e-23 82.9 0.0 2.6e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCD24313.1 - 4.1e-14 52.7 0.3 1.2e-13 51.3 0.3 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CCD24313.1 - 2.7e-06 27.2 0.0 6.4e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 CCD24313.1 - 6.5e-06 26.5 0.1 0.00041 20.8 0.0 2.7 2 0 0 2 2 2 1 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 CCD24313.1 - 0.0053 16.8 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1825 PF08855.10 CCD24313.1 - 0.17 11.8 1.7 3.5 7.6 0.0 3.4 5 0 0 5 5 5 0 Domain of unknown function (DUF1825) Med14 PF08638.11 CCD24314.1 - 5.5e-55 185.8 2.8 1.6e-54 184.2 2.8 1.9 1 0 0 1 1 1 1 Mediator complex subunit MED14 VASt PF16016.5 CCD24315.1 - 7.6e-34 117.3 0.4 1.9e-33 116.0 0.4 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CCD24315.1 - 6.1e-08 32.5 0.3 1.7e-07 31.1 0.3 1.8 1 0 0 1 1 1 1 GRAM domain Orf78 PF06024.12 CCD24315.1 - 2 8.8 12.3 0.89 9.9 1.8 3.2 3 0 0 3 3 3 0 Orf78 (ac78) OTU PF02338.19 CCD24316.1 - 3.4e-08 34.0 0.0 5.7e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DUF104 PF01954.16 CCD24316.1 - 0.072 13.5 0.0 0.3 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF104 DUF3310 PF11753.8 CCD24316.1 - 0.11 12.7 1.1 0.19 12.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknwon function (DUF3310) zf-C2H2_jaz PF12171.8 CCD24317.1 - 3.9e-10 39.7 5.1 3.9e-10 39.7 5.1 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CCD24317.1 - 8.3e-05 22.9 0.1 0.00016 22.0 0.1 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Cytokin-bind PF09265.10 CCD24317.1 - 0.059 12.8 0.1 0.076 12.4 0.1 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding zf-C2H2_4 PF13894.6 CCD24317.1 - 0.065 14.1 1.7 0.1 13.5 0.8 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-AD PF07776.15 CCD24317.1 - 0.086 13.1 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) zf-C2HE PF16278.5 CCD24317.1 - 0.31 11.5 4.4 1.1 9.8 1.0 2.8 3 1 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Ribosomal_L16 PF00252.18 CCD24318.1 - 3.3e-41 140.4 0.1 4.1e-41 140.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RCC1 PF00415.18 CCD24319.1 - 2e-22 79.5 0.1 4.2e-05 24.1 0.1 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CCD24319.1 - 5.3e-12 45.2 6.4 6.1e-07 29.1 0.1 4.4 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat V-SNARE_C PF12352.8 CCD24320.1 - 3.9e-09 36.7 2.6 3.9e-09 36.7 2.6 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CCD24320.1 - 0.00052 19.9 1.1 0.00052 19.9 1.1 2.9 2 1 1 3 3 3 1 Sec20 DUF4407 PF14362.6 CCD24320.1 - 0.013 14.8 1.8 0.022 14.1 1.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ERM PF00769.19 CCD24320.1 - 1.2 8.9 9.0 0.22 11.3 4.7 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Lectin_leg-like PF03388.13 CCD24322.1 - 1.3e-49 168.7 0.2 1.8e-49 168.1 0.2 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CCD24322.1 - 0.00015 21.8 0.5 0.00042 20.4 0.5 1.7 1 1 0 1 1 1 1 Bacterial lectin Sir1 PF11603.8 CCD24323.1 - 1.4e-35 122.4 2.9 5.2e-35 120.5 2.9 2.1 1 0 0 1 1 1 1 Regulatory protein Sir1 Helicase_C PF00271.31 CCD24323.1 - 1.1e-10 41.9 0.1 2.9e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCD24323.1 - 1.1e-08 35.0 0.0 1.3e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CCD24323.1 - 0.057 13.4 0.0 0.31 11.0 0.0 2.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCD24323.1 - 0.11 12.8 0.0 0.42 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF3288 PF11691.8 CCD24324.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3288) MFS_1 PF07690.16 CCD24325.1 - 1.1e-13 50.9 5.6 4.7e-13 48.8 5.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily T6PP_N PF18572.1 CCD24325.1 - 0.028 14.2 0.4 0.06 13.2 0.4 1.5 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF1542 PF07564.11 CCD24325.1 - 3.9 7.7 6.3 1.8 8.7 1.8 2.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) Sec23_trunk PF04811.15 CCD24326.1 - 1.4e-66 224.5 0.0 2.1e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CCD24326.1 - 1.3e-26 93.2 0.2 2.9e-26 92.0 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CCD24326.1 - 2.3e-23 82.0 0.3 9.1e-23 80.0 0.1 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 CCD24326.1 - 3.5e-11 42.9 0.0 7.1e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 CCD24326.1 - 1.3e-08 34.8 8.8 3.4e-08 33.4 8.8 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 CCD24326.1 - 0.038 13.4 1.6 0.083 12.3 1.6 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain NBP1 PF08537.10 CCD24327.1 - 1e-43 150.1 37.7 3.3e-41 141.8 37.7 2.1 1 1 0 1 1 1 1 Fungal Nap binding protein NBP1 DUF1645 PF07816.11 CCD24327.1 - 0.016 15.8 6.9 1.7 9.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) Putative_PNPOx PF01243.20 CCD24328.1 - 9.5e-17 61.0 0.0 2e-16 60.0 0.0 1.5 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DBD_HTH PF18430.1 CCD24328.1 - 1.9 8.4 4.3 0.8 9.5 0.2 2.3 2 1 1 3 3 3 0 Putative DNA-binding domain PWWP PF00855.17 CCD24329.1 - 4.4e-17 62.3 0.1 1.2e-16 60.9 0.1 1.8 1 0 0 1 1 1 1 PWWP domain Med26 PF08711.11 CCD24329.1 - 0.017 15.2 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 TFIIS helical bundle-like domain PBP1_TM PF14812.6 CCD24329.1 - 9.7 6.6 10.2 33 5.0 10.2 2.0 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4064 PF13273.6 CCD24330.1 - 0.017 15.4 0.6 0.024 14.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF997 PF06196.12 CCD24330.1 - 0.045 13.8 1.2 4.4 7.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF997) DUF4131 PF13567.6 CCD24330.1 - 0.049 13.3 0.2 0.053 13.2 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Med10 PF09748.9 CCD24331.1 - 1.5e-38 131.4 0.4 2.4e-38 130.8 0.4 1.3 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex FapA PF03961.13 CCD24331.1 - 0.076 11.6 0.8 0.096 11.3 0.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A EF-G-binding_N PF07299.11 CCD24331.1 - 0.15 12.6 2.5 0.68 10.5 0.2 2.7 2 1 1 3 3 3 0 Elongation factor G-binding protein, N-terminal GAT PF03127.14 CCD24331.1 - 0.16 12.3 4.6 0.52 10.6 0.1 2.7 3 0 0 3 3 3 0 GAT domain DUF2203 PF09969.9 CCD24331.1 - 0.19 12.4 2.4 7.9 7.2 0.0 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4404 PF14357.6 CCD24331.1 - 0.78 10.4 5.4 41 4.9 0.6 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) NPV_P10 PF05531.12 CCD24331.1 - 1.5 9.3 7.1 29 5.2 1.5 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RIC3 PF15361.6 CCD24331.1 - 1.9 8.9 5.1 0.49 10.8 0.3 2.1 2 1 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Ras PF00071.22 CCD24332.1 - 1.7e-53 180.6 0.0 2e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD24332.1 - 5.6e-20 71.7 0.0 1.2e-19 70.6 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD24332.1 - 4e-05 23.1 0.0 5.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Fmp27 PF10344.9 CCD24333.1 - 2.1e-115 386.8 61.2 2.1e-115 386.8 61.2 1.7 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.9 CCD24333.1 - 3.2e-113 379.1 7.0 3.2e-113 379.1 7.0 2.0 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 CCD24333.1 - 1.2e-77 261.8 13.5 2.1e-54 185.2 9.1 2.6 1 1 1 2 2 2 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 CCD24333.1 - 7.2e-56 188.6 0.1 1.9e-55 187.3 0.1 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CCD24333.1 - 9.7e-51 171.7 0.6 8.7e-50 168.6 0.5 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 CCD24333.1 - 8.6e-32 109.9 0.0 5.1e-31 107.4 0.0 2.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain B5 PF03484.15 CCD24333.1 - 0.13 12.6 0.0 0.55 10.6 0.0 2.2 1 0 0 1 1 1 0 tRNA synthetase B5 domain RRM_1 PF00076.22 CCD24334.1 - 0.00038 20.2 0.0 0.00072 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pox_Ag35 PF03286.14 CCD24334.1 - 0.71 9.6 11.2 1.3 8.8 11.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RGS PF00615.19 CCD24335.1 - 3e-16 59.7 2.9 3.1e-11 43.6 0.4 2.6 2 0 0 2 2 2 2 Regulator of G protein signaling domain DEP PF00610.21 CCD24335.1 - 1.5e-12 47.4 0.0 1.6e-11 44.1 0.0 2.6 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Zn_clus PF00172.18 CCD24336.1 - 2.7e-08 33.8 10.4 5.4e-08 32.8 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2054 PF10218.9 CCD24336.1 - 0.029 14.5 3.8 0.071 13.2 3.8 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2054) zf-3CxxC_2 PF17180.4 CCD24336.1 - 0.28 12.0 5.1 0.98 10.2 5.1 1.9 1 0 0 1 1 1 0 Zinc-binding domain PBP1_TM PF14812.6 CCD24336.1 - 1.6 9.1 6.4 5.2 7.5 6.4 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2968 PF11180.8 CCD24336.1 - 5 6.7 8.6 0.054 13.1 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) MFS_1 PF07690.16 CCD24337.1 - 5.6e-22 78.1 21.0 1.9e-14 53.4 18.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CCD24337.1 - 0.0023 16.3 2.5 0.0023 16.3 2.5 2.9 2 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 CCD24337.1 - 0.0025 16.8 13.9 0.0025 16.8 13.9 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 CCD24337.1 - 0.0081 15.1 19.4 0.01 14.7 4.4 2.7 3 0 0 3 3 3 2 MFS_1 like family MFS_2 PF13347.6 CCD24337.1 - 1.1 7.7 36.6 0.025 13.1 13.3 3.6 2 2 1 3 3 3 0 MFS/sugar transport protein Ribosomal_S7 PF00177.21 CCD24338.1 - 1.2e-36 125.6 2.1 1.7e-36 125.1 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e GCV_T PF01571.21 CCD24339.1 - 0.12 11.8 0.0 11 5.3 0.0 2.3 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain ATP-synt_ab PF00006.25 CCD24340.1 - 7.1e-63 212.1 0.0 1.1e-62 211.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CCD24340.1 - 2.1e-23 82.6 1.0 5.8e-23 81.2 1.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 CCD24340.1 - 0.0017 17.8 0.2 0.0028 17.0 0.2 1.4 1 0 0 1 1 1 1 KaiC NB-ARC PF00931.22 CCD24340.1 - 0.0098 15.1 0.7 0.078 12.1 0.1 2.1 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 CCD24340.1 - 0.037 13.9 0.2 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 CCD24340.1 - 0.039 13.9 0.1 0.09 12.7 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 CCD24340.1 - 0.045 14.2 0.1 0.63 10.5 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T3SS_ATPase_C PF18269.1 CCD24340.1 - 0.05 13.5 0.6 0.31 10.9 0.6 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA_16 PF13191.6 CCD24340.1 - 0.07 13.5 0.1 0.28 11.6 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 CCD24340.1 - 0.096 13.1 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 CCD24340.1 - 0.18 11.8 0.1 0.49 10.4 0.1 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 CCD24340.1 - 0.51 10.7 4.3 0.49 10.7 0.2 2.6 3 0 0 3 3 3 0 AAA domain JmjC PF02373.22 CCD24341.1 - 7.5e-37 126.3 0.9 3e-36 124.3 0.9 2.1 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 CCD24341.1 - 1e-09 38.2 0.0 4.2e-09 36.2 0.0 2.2 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 CCD24341.1 - 0.0021 17.9 14.1 0.0021 17.9 14.1 2.4 2 0 0 2 2 2 1 PHD-finger Ilm1 PF10311.9 CCD24342.1 - 6.5e-11 42.2 8.4 4.1e-08 33.1 8.4 2.1 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Rpn3_C PF08375.11 CCD24343.1 - 7.4e-22 77.6 0.1 1.9e-21 76.2 0.1 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 CCD24343.1 - 3.8e-20 72.4 1.3 6.6e-20 71.6 0.2 2.0 2 0 0 2 2 2 1 PCI domain Peptidase_M48_N PF16491.5 CCD24344.1 - 1.3e-58 198.0 10.2 1.3e-58 198.0 10.2 2.2 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CCD24344.1 - 1.5e-42 145.6 0.5 5.3e-42 143.8 0.5 1.8 1 1 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 CCD24344.1 - 0.03 13.9 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) SprT-like PF10263.9 CCD24344.1 - 0.051 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 SprT-like family TRAM_LAG1_CLN8 PF03798.16 CCD24345.1 - 1.4e-33 116.3 23.4 1.4e-33 116.3 23.4 1.5 2 0 0 2 2 2 1 TLC domain PfkB PF00294.24 CCD24346.1 - 4.7e-73 246.1 0.9 7e-73 245.6 0.9 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CCD24346.1 - 0.00034 20.1 0.0 0.00056 19.4 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase ANAPC1 PF12859.7 CCD24346.1 - 0.048 14.2 0.4 0.075 13.6 0.4 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 AMP_N PF05195.16 CCD24346.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain Na_Ca_ex PF01699.24 CCD24347.1 - 2.2e-50 170.5 31.9 4e-28 98.3 6.2 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein PIG-P PF08510.12 CCD24347.1 - 1.8e-06 27.9 4.1 0.16 11.9 0.0 3.7 3 0 0 3 3 3 3 PIG-P Lipase_3 PF01764.25 CCD24348.1 - 1.1e-35 122.6 0.0 3.8e-35 120.8 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.8 CCD24348.1 - 0.027 14.0 1.0 1.8 8.1 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 CCD24348.1 - 0.047 13.5 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3173 PF11372.8 CCD24348.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) Abhydrolase_6 PF12697.7 CCD24348.1 - 0.15 12.6 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF5137 PF17220.3 CCD24349.1 - 1.8e-18 67.1 6.6 2.2e-18 66.9 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF5137) CPSase_L_D2 PF02786.17 CCD24350.1 - 2.3e-112 373.6 0.0 1.8e-84 282.5 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 CCD24350.1 - 1.9e-40 138.0 0.2 4e-40 137.0 0.2 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 CCD24350.1 - 1.5e-18 66.9 0.1 1.7e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 CCD24350.1 - 1.6e-15 57.0 0.0 6.7e-08 32.3 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 CCD24350.1 - 1.9e-15 56.9 0.6 2.8e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.11 CCD24350.1 - 3.3e-05 23.6 0.1 0.049 13.2 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.19 CCD24350.1 - 0.0012 18.6 0.2 2.6 7.8 0.0 3.0 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 CCD24350.1 - 0.0038 16.7 0.0 0.086 12.3 0.1 2.5 2 0 0 2 2 2 1 ATP-grasp domain MGS PF02142.22 CCD24350.1 - 0.013 15.7 0.0 0.05 13.8 0.0 2.1 1 0 0 1 1 1 0 MGS-like domain MCPsignal PF00015.21 CCD24350.1 - 0.073 12.9 0.2 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Yippee-Mis18 PF03226.14 CCD24351.1 - 5.4e-14 52.3 1.9 9.3e-14 51.5 1.9 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2079 PF09852.9 CCD24351.1 - 0.11 11.3 0.2 0.13 11.1 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) NOA36 PF06524.12 CCD24351.1 - 2 7.7 8.1 3.7 6.8 8.1 1.4 1 0 0 1 1 1 0 NOA36 protein Myotub-related PF06602.14 CCD24352.1 - 2.2e-137 457.7 1.2 2.8e-137 457.4 1.2 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 CCD24352.1 - 0.0012 18.8 0.1 0.0039 17.1 0.1 2.0 1 1 0 1 1 1 1 GRAM domain DSPc PF00782.20 CCD24352.1 - 0.021 14.6 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CCD24352.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family CMD PF02627.20 CCD24353.1 - 5e-05 23.3 0.0 0.00015 21.7 0.0 1.8 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Ribosomal_S7 PF00177.21 CCD24354.1 - 2e-34 118.4 0.7 2.9e-34 117.9 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e TcdB_N PF12918.7 CCD24354.1 - 0.12 12.6 1.9 0.42 10.9 0.2 2.3 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain ELFV_dehydrog PF00208.21 CCD24354.1 - 0.14 11.9 0.2 0.64 9.7 0.0 1.9 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Sod_Cu PF00080.20 CCD24356.1 - 4.4e-47 159.8 4.5 5.1e-47 159.6 4.5 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) ESCRT-II PF05871.12 CCD24357.1 - 1.2e-41 142.3 5.8 1.5e-41 141.9 5.8 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Sod_Fe_C PF02777.18 CCD24358.1 - 2.8e-14 53.1 2.1 7.9e-09 35.6 0.6 2.5 1 1 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Scramblase PF03803.15 CCD24359.1 - 1e-68 230.9 0.1 1.4e-68 230.5 0.1 1.1 1 0 0 1 1 1 1 Scramblase CdiI PF07262.11 CCD24359.1 - 0.05 13.4 0.1 0.092 12.5 0.1 1.3 1 0 0 1 1 1 0 CDI immunity protein Peptidase_C12 PF01088.21 CCD24362.1 - 9.2e-48 162.8 0.1 1.1e-47 162.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 LCAT PF02450.15 CCD24363.1 - 6.4e-06 25.6 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 CCD24363.1 - 1.6e-05 24.8 0.0 6.9e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 CCD24363.1 - 3.4e-05 23.2 0.0 0.0001 21.6 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCD24363.1 - 8.6e-05 23.2 0.0 0.00016 22.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CCD24363.1 - 0.00022 20.9 0.0 0.00053 19.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CCD24363.1 - 0.0023 17.8 0.3 0.0055 16.6 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase DUF900 PF05990.12 CCD24363.1 - 0.0057 16.2 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.7 CCD24363.1 - 0.018 14.8 0.0 0.053 13.3 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Palm_thioest PF02089.15 CCD24363.1 - 0.09 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Palmitoyl protein thioesterase BUD22 PF09073.10 CCD24363.1 - 0.091 12.1 11.0 0.14 11.4 11.0 1.2 1 0 0 1 1 1 0 BUD22 DUF2052 PF09747.9 CCD24363.1 - 0.56 10.3 9.9 1.2 9.3 9.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Mem_trans PF03547.18 CCD24363.1 - 0.75 8.1 3.9 1.2 7.5 3.9 1.2 1 0 0 1 1 1 0 Membrane transport protein Plasmodium_Vir PF05795.11 CCD24363.1 - 2.6 7.4 7.4 4.4 6.6 7.4 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein zf-CSL PF05207.13 CCD24364.1 - 1.3e-17 63.3 0.3 2.6e-17 62.3 0.3 1.5 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 CCD24364.1 - 2.3e-17 62.9 1.6 5.7e-17 61.6 1.6 1.7 1 1 0 1 1 1 1 DnaJ domain RPT PF13446.6 CCD24364.1 - 0.023 14.6 0.1 7.9 6.5 0.0 2.5 2 0 0 2 2 2 0 A repeated domain in UCH-protein Acetyltransf_11 PF13720.6 CCD24364.1 - 0.075 13.5 0.1 1 9.9 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Mu-like_Com PF10122.9 CCD24364.1 - 0.098 12.1 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 Mu-like prophage protein Com Mito_carr PF00153.27 CCD24365.1 - 2.2e-71 235.9 3.7 3.4e-23 81.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Ysc84 PF04366.12 CCD24365.1 - 0.00067 19.4 2.8 0.0015 18.3 2.7 1.6 1 1 0 1 1 1 1 Las17-binding protein actin regulator Fip1 PF05182.13 CCD24367.1 - 4.2e-20 71.0 0.3 7.7e-20 70.1 0.3 1.5 1 0 0 1 1 1 1 Fip1 motif PH PF00169.29 CCD24368.1 - 6.4e-08 33.1 0.5 3.7e-07 30.6 0.0 2.8 2 0 0 2 2 2 1 PH domain PUF PF00806.19 CCD24369.1 - 1.3e-28 97.0 1.8 1.1e-05 24.8 0.0 6.7 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat RRM_1 PF00076.22 CCD24369.1 - 5.6e-07 29.3 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Preseq_ALAS PF09029.10 CCD24370.1 - 0.21 12.1 0.3 1.5 9.3 0.0 2.5 3 0 0 3 3 3 0 5-aminolevulinate synthase presequence BIR PF00653.21 CCD24371.1 - 1.3e-06 28.9 10.7 4.2e-05 24.1 1.8 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Evr1_Alr PF04777.13 CCD24372.1 - 2.9e-23 82.2 0.4 5.3e-23 81.4 0.4 1.4 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC1 PF18769.1 CCD24372.1 - 0.0093 16.2 0.1 0.017 15.4 0.1 1.5 1 0 0 1 1 1 1 APOBEC1 O-antigen_lig PF13425.6 CCD24372.1 - 0.065 12.0 0.5 0.077 11.8 0.5 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein G-gamma PF00631.22 CCD24373.1 - 1.6e-25 88.9 0.1 2.5e-25 88.3 0.1 1.3 1 0 0 1 1 1 1 GGL domain JAKMIP_CC3 PF16034.5 CCD24373.1 - 0.17 11.8 3.7 0.24 11.3 3.7 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain Aldo_ket_red PF00248.21 CCD24374.1 - 7.7e-45 153.3 0.1 9.5e-45 153.0 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NT5C PF06941.12 CCD24374.1 - 0.0072 16.2 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) ENTH PF01417.20 CCD24375.1 - 1.2e-38 132.0 0.4 1.2e-38 132.0 0.4 1.8 2 0 0 2 2 2 1 ENTH domain Sel1 PF08238.12 CCD24376.1 - 8.3e-25 86.7 0.3 3.6e-06 27.5 0.0 7.6 7 0 0 7 7 7 4 Sel1 repeat TPR_6 PF13174.6 CCD24376.1 - 1.4e-05 25.4 0.5 3.5 8.5 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCD24376.1 - 4.9e-05 23.8 0.1 0.16 12.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCD24376.1 - 0.00051 20.0 2.8 0.13 12.5 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CCD24376.1 - 0.0043 16.7 1.0 0.019 14.6 0.1 2.7 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 CCD24376.1 - 0.0087 16.3 0.1 1.7 9.0 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCD24376.1 - 0.0098 15.7 11.9 0.22 11.4 0.1 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 CCD24376.1 - 0.011 16.4 0.0 0.2 12.3 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCD24376.1 - 0.012 15.6 0.1 0.29 11.2 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CCD24376.1 - 0.02 15.7 0.0 16 6.6 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat Turandot PF07240.11 CCD24376.1 - 0.025 14.5 1.7 2.1 8.4 0.3 2.9 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot TPR_2 PF07719.17 CCD24376.1 - 0.027 14.6 12.5 0.35 11.1 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD24376.1 - 0.052 13.8 0.9 0.63 10.3 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 CCD24376.1 - 0.12 12.0 0.2 0.43 10.3 0.1 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 CCD24376.1 - 0.29 11.1 0.9 32 4.6 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat WD40 PF00400.32 CCD24377.1 - 1.1e-19 70.4 17.3 8e-05 23.3 0.3 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD24377.1 - 3.9e-06 27.1 5.6 0.053 13.8 0.2 4.8 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 CCD24377.1 - 0.035 14.0 0.9 0.035 14.0 0.9 2.1 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 CCD24377.1 - 0.072 12.0 0.3 7 5.5 0.0 3.5 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PNP_UDP_1 PF01048.20 CCD24378.1 - 1.2e-43 149.0 0.0 1.5e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Cyclin_N PF00134.23 CCD24379.1 - 1.1e-44 151.2 0.3 2.5e-44 150.1 0.3 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCD24379.1 - 1.8e-32 111.9 0.4 4.5e-32 110.6 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain zf-C2H2_10 PF16588.5 CCD24380.1 - 7.4e-06 25.6 2.4 1.2e-05 24.9 2.4 1.3 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC_4 PF14392.6 CCD24380.1 - 0.56 10.0 2.7 0.52 10.1 1.2 1.7 2 0 0 2 2 2 0 Zinc knuckle rve PF00665.26 CCD24382.1 - 7.3e-15 55.2 0.0 9.7e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 CCD24382.1 - 0.074 12.8 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Flo11 PF10182.9 CCD24383.1 - 3.6e-69 231.7 2.2 3.6e-69 231.7 2.2 2.2 2 0 0 2 2 2 1 Flo11 domain MucB_RseB_C PF17188.4 CCD24383.1 - 0.004 17.3 0.1 1.4 9.2 0.0 2.6 1 1 1 2 2 2 2 MucB/RseB C-terminal domain HALZ PF02183.18 CCD24384.1 - 0.0036 17.5 0.3 0.012 15.8 0.3 2.0 1 0 0 1 1 1 1 Homeobox associated leucine zipper SUIM_assoc PF16619.5 CCD24384.1 - 0.0065 16.5 0.9 0.014 15.4 0.9 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF4770 PF15994.5 CCD24384.1 - 0.013 15.7 1.8 0.013 15.7 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) MIT PF04212.18 CCD24384.1 - 0.089 12.9 1.9 0.11 12.5 0.3 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Spectrin PF00435.21 CCD24384.1 - 0.78 10.3 14.7 0.054 14.0 1.6 2.8 2 1 0 2 2 2 0 Spectrin repeat Uso1_p115_C PF04871.13 CCD24384.1 - 0.86 10.0 17.3 0.28 11.5 2.7 2.6 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Csm2_III-A PF03750.13 CCD24384.1 - 1.4 9.8 8.8 0.59 11.0 0.5 2.5 2 1 0 2 2 2 0 Csm2 Type III-A Prp18 PF02840.15 CCD24384.1 - 6.2 6.9 8.7 0.14 12.2 0.7 2.3 2 1 1 3 3 3 0 Prp18 domain Tubulin PF00091.25 CCD24385.1 - 1.1e-62 211.8 0.8 2e-62 210.9 0.2 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CCD24385.1 - 1.2e-19 70.8 0.3 2.4e-19 69.7 0.3 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CCD24385.1 - 1.9e-06 28.2 0.6 6.5e-06 26.4 0.6 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CCD24385.1 - 0.1 11.8 0.3 0.24 10.6 0.2 1.6 1 1 0 1 1 1 0 Tubulin like Glyco_hydro_16 PF00722.21 CCD24386.1 - 3.1e-45 153.8 0.4 5.2e-45 153.1 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Cellulase PF00150.18 CCD24387.1 - 1.8e-14 53.8 0.3 1.8e-14 53.8 0.3 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF3783 PF12646.7 CCD24387.1 - 0.21 11.6 0.1 1.7 8.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3783) SNF2_N PF00176.23 CCD24388.1 - 3.2e-54 184.0 0.0 8.3e-54 182.6 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCD24388.1 - 2.2e-15 57.0 0.0 7.2e-15 55.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 CCD24388.1 - 3.7e-05 23.5 1.6 0.0001 22.1 1.6 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CCD24388.1 - 8.8e-05 22.4 5.0 0.00021 21.2 5.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CCD24388.1 - 0.00019 21.2 1.5 0.00044 20.0 1.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCD24388.1 - 0.00039 20.2 3.1 0.00096 19.0 3.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCD24388.1 - 0.0029 17.9 5.0 0.0063 16.8 5.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CCD24388.1 - 0.0072 16.3 2.5 0.016 15.2 2.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 CCD24388.1 - 0.014 15.4 0.0 0.014 15.4 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 CCD24388.1 - 0.036 13.9 5.2 0.079 12.9 5.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 23S_rRNA_IVP PF05635.11 CCD24388.1 - 0.042 14.1 1.0 0.13 12.5 1.0 1.9 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein YtxH PF12732.7 CCD24388.1 - 6.9 7.3 8.4 51 4.5 5.0 3.7 2 1 1 3 3 3 0 YtxH-like protein HRI1 PF16815.5 CCD24389.1 - 5.1e-42 144.1 0.0 5.7e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Protein HRI1 Hydantoinase_B PF02538.14 CCD24391.1 - 3.9e-205 682.1 0.0 4.9e-205 681.8 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 CCD24391.1 - 5.6e-101 337.6 0.6 1.3e-100 336.5 0.0 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CCD24391.1 - 5.9e-58 195.5 0.6 4.4e-56 189.4 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DUF2482 PF10655.9 CCD24391.1 - 0.17 12.4 1.3 0.33 11.5 0.2 2.0 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2482) Ribosomal_L6 PF00347.23 CCD24391.1 - 0.67 10.7 4.1 2.9 8.6 0.2 3.4 4 0 0 4 4 4 0 Ribosomal protein L6 Ribo_biogen_C PF04034.13 CCD24393.1 - 5.8e-50 168.3 0.0 9.4e-50 167.6 0.0 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CCD24393.1 - 5.3e-14 51.7 0.3 1.1e-13 50.8 0.3 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI RHS_repeat PF05593.14 CCD24393.1 - 0.21 12.1 0.9 27 5.4 0.0 3.2 3 1 0 3 3 3 0 RHS Repeat VPS9 PF02204.18 CCD24394.1 - 8.6e-09 35.6 1.3 2.6e-08 34.0 1.3 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 CCD24394.1 - 1.4e-05 25.6 5.2 0.13 12.9 0.3 3.8 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CCD24394.1 - 0.017 15.4 0.0 0.97 9.8 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCD24394.1 - 0.11 13.2 1.1 5.7 7.9 0.0 4.2 5 0 0 5 5 5 0 Ankyrin repeat SGTA_dimer PF16546.5 CCD24395.1 - 4.4e-22 77.6 0.8 4.4e-22 77.6 0.8 2.7 1 1 1 2 2 2 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 CCD24395.1 - 3.7e-20 70.9 7.0 3.3e-07 29.8 0.3 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCD24395.1 - 9.8e-17 59.7 5.6 7.4e-05 22.6 0.3 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCD24395.1 - 2e-14 53.0 5.5 0.00062 19.4 0.5 3.6 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 CCD24395.1 - 6.8e-09 35.2 12.2 0.00041 20.3 0.6 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCD24395.1 - 7.9e-08 32.2 0.5 0.0034 17.7 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCD24395.1 - 7.8e-07 29.3 2.4 0.023 15.0 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCD24395.1 - 3.8e-06 26.9 1.1 0.11 12.5 0.0 3.6 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 CCD24395.1 - 8.4e-06 26.2 0.1 0.19 12.6 0.1 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CCD24395.1 - 1.7e-05 25.4 0.1 0.0016 19.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CCD24395.1 - 2.2e-05 24.2 1.2 0.27 11.1 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCD24395.1 - 2.4e-05 24.8 0.3 0.0028 18.1 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 CCD24395.1 - 0.00019 21.9 0.0 0.0012 19.3 0.0 2.2 2 1 0 3 3 3 1 Bacterial transcriptional activator domain TPR_7 PF13176.6 CCD24395.1 - 0.00054 19.8 0.3 2.6 8.3 0.1 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat STI1 PF17830.1 CCD24395.1 - 0.0048 16.8 12.9 0.17 11.9 2.0 2.6 1 1 1 2 2 2 2 STI1 domain GerD PF17898.1 CCD24395.1 - 0.006 16.5 2.7 0.058 13.4 2.4 2.6 1 1 0 1 1 1 1 Spore germination GerD central core domain TPR_6 PF13174.6 CCD24395.1 - 0.0099 16.5 0.5 2.2 9.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CCD24395.1 - 0.037 14.2 0.0 0.12 12.5 0.0 1.9 2 1 0 2 2 1 0 Tetratricopeptide repeat DUF3856 PF12968.7 CCD24395.1 - 0.06 13.4 5.3 6.3 6.9 0.2 3.6 2 2 1 3 3 3 0 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 CCD24395.1 - 0.14 12.4 2.6 1.2 9.4 2.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 CCD24395.1 - 4.2 7.5 9.2 49 4.1 0.3 4.2 3 2 1 4 4 4 0 MIT (microtubule interacting and transport) domain Sugar_tr PF00083.24 CCD24396.1 - 1.4e-162 541.7 31.7 1.6e-162 541.5 31.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD24396.1 - 7.1e-33 114.0 21.5 7.1e-33 114.0 21.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 CCD24396.1 - 4.2 7.7 8.6 8 6.8 3.5 3.5 2 2 2 4 4 4 0 Domain of unknown function (DUF1772) Pirin PF02678.16 CCD24397.1 - 1.6e-29 102.0 0.1 3e-28 98.0 0.0 2.2 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 CCD24397.1 - 1.4e-18 67.1 0.0 6e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 CCD24397.1 - 0.00019 21.1 1.8 0.00032 20.3 0.8 1.9 2 0 0 2 2 2 1 Cupin domain DUF4441 PF14536.6 CCD24397.1 - 0.069 13.4 0.5 0.15 12.3 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) PsbM PF05151.12 CCD24397.1 - 0.25 11.2 2.5 0.58 10.0 2.5 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) Ras PF00071.22 CCD24398.1 - 5.5e-56 188.6 0.3 6.5e-56 188.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD24398.1 - 7.1e-34 116.6 0.1 1e-33 116.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD24398.1 - 1.9e-15 56.7 0.0 2.2e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCD24398.1 - 3.2e-07 29.9 0.2 3.9e-07 29.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCD24398.1 - 9.7e-07 28.9 0.1 2.3e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCD24398.1 - 2.6e-06 27.1 0.2 8.3e-05 22.2 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CCD24398.1 - 0.00014 21.3 0.2 0.00019 20.9 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CCD24398.1 - 0.00015 21.7 0.1 0.029 14.3 0.0 2.4 1 1 2 3 3 3 1 RsgA GTPase ATP_bind_1 PF03029.17 CCD24398.1 - 0.0014 18.5 0.3 0.028 14.2 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 CCD24398.1 - 0.005 17.1 0.0 0.011 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 CCD24398.1 - 0.0059 16.2 0.0 0.016 14.8 0.0 1.6 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 CCD24398.1 - 0.015 15.0 0.3 0.12 12.1 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 CCD24398.1 - 0.016 14.6 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 CCD24398.1 - 0.017 15.5 0.1 0.021 15.2 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 CCD24398.1 - 0.024 14.6 0.1 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 CCD24398.1 - 0.026 14.5 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 CCD24398.1 - 0.028 13.9 0.1 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CCD24398.1 - 0.029 14.1 0.2 0.076 12.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 CCD24398.1 - 0.034 13.4 0.3 0.22 10.8 0.0 2.1 2 1 0 2 2 2 0 Septin ABC_tran PF00005.27 CCD24398.1 - 0.2 12.2 0.4 0.31 11.6 0.4 1.7 1 1 0 1 1 1 0 ABC transporter DNA_pol_A_exo1 PF01612.20 CCD24399.1 - 5.8e-46 156.4 1.2 7.3e-45 152.8 0.1 2.4 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.12 CCD24399.1 - 6.4e-21 74.9 4.8 6.4e-21 74.9 4.8 3.4 3 1 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.23 CCD24399.1 - 4.9e-12 45.7 0.0 1.1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 HRDC domain NPR2 PF06218.11 CCD24400.1 - 2.9e-124 415.2 16.9 8.1e-124 413.7 16.9 1.8 1 1 0 1 1 1 1 Nitrogen permease regulator 2 FAM60A PF15396.6 CCD24400.1 - 2.2 8.2 14.1 6.8 6.6 0.1 3.1 3 0 0 3 3 3 0 Protein Family FAM60A Kinesin PF00225.23 CCD24401.1 - 2.8e-96 322.3 20.6 4.4e-61 206.7 6.8 3.3 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CCD24401.1 - 1.6e-21 76.8 0.3 1.6e-21 76.8 0.3 2.9 2 1 0 2 2 2 1 Microtubule binding Cpn60_TCP1 PF00118.24 CCD24402.1 - 1.5e-86 291.0 9.8 3.4e-86 289.9 9.8 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family RNA_pol_I_TF PF04090.12 CCD24403.1 - 2.8e-70 235.9 2.2 2.8e-70 235.9 2.2 2.5 2 0 0 2 2 2 1 RNA polymerase I specific initiation factor IMS_HHH PF11798.8 CCD24403.1 - 0.13 12.7 0.2 0.37 11.2 0.2 1.7 1 0 0 1 1 1 0 IMS family HHH motif DDR PF08841.10 CCD24403.1 - 0.31 10.0 0.6 0.48 9.3 0.6 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Zn_clus PF00172.18 CCD24404.1 - 1.2e-08 34.9 10.4 1.2e-08 34.9 10.4 2.0 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.21 CCD24405.1 - 2.2e-19 69.9 0.0 3.1e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCD24405.1 - 4.4e-13 48.9 0.1 6.4e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CCD24405.1 - 5.5e-07 29.3 0.4 5.7e-06 26.0 0.4 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CCD24405.1 - 9.6e-07 28.9 0.0 2.9e-06 27.3 0.0 1.8 2 1 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CCD24405.1 - 1.1e-06 28.0 0.0 1.1e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 CCD24405.1 - 2e-05 24.1 0.5 0.00036 20.1 0.0 2.6 2 2 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 CCD24405.1 - 0.00013 21.2 0.1 0.0025 17.0 0.1 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CCD24405.1 - 0.00018 21.2 0.1 0.0038 16.8 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 CCD24405.1 - 0.011 15.7 0.0 0.024 14.5 0.0 1.5 1 1 0 1 1 1 0 KR domain F420_oxidored PF03807.17 CCD24405.1 - 0.014 16.0 0.0 0.042 14.4 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.6 CCD24405.1 - 0.071 12.7 0.0 0.3 10.6 0.0 2.0 2 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase PLA2_B PF01735.18 CCD24406.1 - 1.8e-232 772.1 6.5 2.4e-232 771.6 6.5 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 CCD24406.1 - 0.028 14.6 1.2 0.054 13.7 1.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain TAF4 PF05236.14 CCD24407.1 - 7.9e-55 186.5 3.1 7.9e-55 186.5 3.1 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family MINDY_DUB PF04424.13 CCD24408.1 - 1.1e-29 102.8 0.8 3.2e-29 101.3 0.8 1.8 1 1 0 1 1 1 1 MINDY deubiquitinase Dicty_REP PF05086.12 CCD24408.1 - 0.00068 17.8 0.8 0.00094 17.3 0.8 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein EF-hand_6 PF13405.6 CCD24408.1 - 0.014 15.2 0.0 3.4 7.8 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 CCD24408.1 - 0.018 14.6 0.0 1.3 8.7 0.0 2.7 2 0 0 2 2 2 0 EF hand UPF0240 PF06784.11 CCD24408.1 - 0.04 14.0 0.5 0.082 13.0 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) EF-hand_5 PF13202.6 CCD24408.1 - 0.062 12.8 0.1 8.3 6.1 0.0 2.6 2 0 0 2 2 2 0 EF hand DUF3439 PF11921.8 CCD24408.1 - 0.085 12.8 1.2 0.14 12.1 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CDC45 PF02724.14 CCD24409.1 - 0.33 9.2 9.0 0.38 9.0 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein TbpB_A PF17484.2 CCD24409.1 - 0.7 10.6 9.7 1.3 9.8 9.7 1.4 1 0 0 1 1 1 0 N-Lobe handle Tf-binding protein B SprA-related PF12118.8 CCD24409.1 - 8.6 5.4 14.0 10 5.2 14.0 1.1 1 0 0 1 1 1 0 SprA-related family NUFIP1 PF10453.9 CCD24411.1 - 3.2e-19 68.5 2.0 3.2e-19 68.5 2.0 2.9 3 0 0 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) RRM_1 PF00076.22 CCD24412.1 - 8e-10 38.4 0.1 1.9e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCD24412.1 - 0.0022 17.6 0.0 0.0091 15.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUN PF03856.13 CCD24413.1 - 5.3e-98 327.4 10.7 8.5e-98 326.7 10.7 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF5426 PF17473.2 CCD24414.1 - 0.24 11.7 1.6 0.42 10.9 1.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5426) MFS_1 PF07690.16 CCD24415.1 - 4.4e-39 134.4 15.5 4.4e-39 134.4 15.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCD24415.1 - 4.5e-16 58.8 9.6 1.8e-15 56.8 3.9 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 CCD24415.1 - 8.4e-05 21.2 2.7 0.00013 20.5 2.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 CCD24415.1 - 0.0026 16.8 0.3 0.0048 15.9 0.3 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM DUF4231 PF14015.6 CCD24415.1 - 0.21 12.0 0.9 37 4.9 0.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3784 PF12650.7 CCD24415.1 - 0.78 10.0 0.0 0.78 10.0 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) DnaJ_C PF01556.18 CCD24416.1 - 4.8e-40 137.1 0.2 6.1e-40 136.7 0.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCD24416.1 - 4.5e-27 94.0 1.9 7.2e-27 93.3 1.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CCD24416.1 - 9.8e-16 57.9 16.9 1.7e-15 57.1 16.9 1.4 1 0 0 1 1 1 1 DnaJ central domain DUF2277 PF10041.9 CCD24416.1 - 0.11 12.9 0.3 0.65 10.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) HypA PF01155.19 CCD24416.1 - 0.24 11.4 11.6 2 8.5 2.3 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Gcd10p PF04189.13 CCD24417.1 - 1.7e-99 332.7 1.7 2.2e-99 332.4 1.7 1.1 1 0 0 1 1 1 1 Gcd10p family Mrr_N PF14338.6 CCD24417.1 - 0.023 14.8 0.7 0.71 10.0 0.0 2.5 2 1 0 2 2 2 0 Mrr N-terminal domain RPA_interact_M PF14767.6 CCD24417.1 - 0.21 12.2 1.4 1.1 9.9 0.0 2.5 2 1 0 2 2 2 0 Replication protein A interacting middle Linker_histone PF00538.19 CCD24417.1 - 0.23 11.9 1.6 0.67 10.4 1.6 1.8 1 0 0 1 1 1 0 linker histone H1 and H5 family CREPT PF16566.5 CCD24417.1 - 0.98 9.6 4.1 1.5 9.0 3.4 1.6 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Methyltr_RsmB-F PF01189.17 CCD24418.1 - 1e-81 273.4 0.0 2.5e-81 272.1 0.0 1.7 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CCD24418.1 - 4.3e-08 33.5 0.0 3.2e-07 30.8 0.0 2.5 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 CCD24418.1 - 0.036 14.2 1.7 0.038 14.1 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase Actin PF00022.19 CCD24419.1 - 2.6e-53 181.1 0.0 7.7e-31 107.1 0.0 2.4 2 0 0 2 2 2 2 Actin HemY_N PF07219.13 CCD24420.1 - 0.036 14.3 0.2 0.064 13.5 0.2 1.6 1 1 0 1 1 1 0 HemY protein N-terminus Y_phosphatase2 PF03162.13 CCD24421.1 - 1.7e-51 174.1 0.0 1.9e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CCD24421.1 - 1.2e-05 25.4 0.0 1.3e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Vac7 PF12751.7 CCD24422.1 - 1.4e-28 100.5 12.1 1.2e-22 80.9 0.2 4.8 4 2 0 4 4 4 2 Vacuolar segregation subunit 7 ETRAMP PF09716.10 CCD24422.1 - 0.9 9.6 5.4 1.4 9.0 0.0 3.8 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) DSPc PF00782.20 CCD24423.1 - 1.8e-36 124.9 0.8 5.3e-36 123.4 0.8 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCD24423.1 - 0.0065 16.1 0.0 0.019 14.5 0.0 1.8 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CCD24423.1 - 0.01 16.0 0.5 0.031 14.4 0.0 2.0 2 1 0 2 2 2 0 Inositol hexakisphosphate COG5 PF10392.9 CCD24424.1 - 1.4e-38 132.0 6.3 1.4e-38 132.0 6.3 3.1 3 1 0 3 3 3 1 Golgi transport complex subunit 5 FOXO-TAD PF16676.5 CCD24424.1 - 0.069 13.6 0.3 25 5.4 0.0 3.4 3 0 0 3 3 3 0 Transactivation domain of FOXO protein family DUF2011 PF09428.10 CCD24425.1 - 1.3e-18 67.0 0.1 2.4e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) SseC PF04888.12 CCD24425.1 - 5.4 6.5 6.6 7.3 6.1 6.6 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Sec23_trunk PF04811.15 CCD24426.1 - 2.7e-66 223.6 0.0 6.1e-66 222.5 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CCD24426.1 - 3.8e-22 78.0 0.5 3.8e-22 78.0 0.5 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CCD24426.1 - 1.4e-14 53.8 5.2 2.8e-14 52.9 5.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CCD24426.1 - 2.5e-14 53.8 0.0 5.3e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CCD24426.1 - 1.1e-09 38.0 0.0 6.7e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 Gelsolin repeat DUF3219 PF11514.8 CCD24426.1 - 0.03 14.3 0.5 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3219) UQ_con PF00179.26 CCD24427.1 - 1.2e-39 135.1 0.1 1.6e-39 134.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CCD24427.1 - 0.058 13.7 0.3 0.12 12.6 0.3 1.7 1 1 0 1 1 1 0 RWD domain Alpha-amylase_C PF02806.18 CCD24428.1 - 2e-27 95.5 0.1 7.6e-27 93.6 0.1 2.1 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 CCD24428.1 - 3.4e-16 59.4 0.1 7.8e-16 58.2 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 CCD24428.1 - 3.6e-15 56.4 0.2 1.3e-13 51.2 0.1 2.7 1 1 1 2 2 2 1 Alpha amylase, catalytic domain Glyco_hydro_66 PF13199.6 CCD24428.1 - 0.0073 15.0 0.0 0.015 13.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 66 zf-CCHC PF00098.23 CCD24430.1 - 5.2e-06 26.3 2.2 9.6e-06 25.5 2.2 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF637 PF04830.13 CCD24430.1 - 0.0025 17.7 2.9 0.024 14.5 1.2 2.2 2 0 0 2 2 2 1 Possible hemagglutinin (DUF637) Retrotrans_gag PF03732.17 CCD24430.1 - 0.059 13.7 0.1 0.18 12.1 0.0 1.9 1 1 1 2 2 2 0 Retrotransposon gag protein ApbA_C PF08546.11 CCD24430.1 - 0.06 13.5 0.0 1 9.6 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal 5_3_exonuc PF01367.20 CCD24430.1 - 0.065 13.8 0.1 0.21 12.2 0.0 1.9 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold zf-C2H2_10 PF16588.5 CCD24430.1 - 0.56 10.0 3.4 0.96 9.2 3.4 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger eIF3g PF12353.8 CCD24430.1 - 0.56 10.6 4.5 0.17 12.3 0.9 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_5 PF14787.6 CCD24430.1 - 0.77 9.5 2.7 1.5 8.6 2.7 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Swm2 PF17083.5 CCD24431.1 - 7.5e-46 155.4 5.0 8.6e-46 155.2 5.0 1.0 1 0 0 1 1 1 1 Nucleolar protein Swm2 DUF2373 PF10180.9 CCD24432.1 - 1.7e-27 95.0 0.1 3.6e-27 94.0 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Biotin_carb_C PF02785.19 CCD24432.1 - 0.07 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain CENP-I PF07778.11 CCD24432.1 - 5 5.7 7.0 11 4.5 1.7 2.2 2 0 0 2 2 2 0 Mis6 HAD PF12710.7 CCD24433.1 - 1.7e-08 35.1 0.0 4.4e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 CCD24433.1 - 0.0024 17.3 0.0 0.78 9.1 0.0 2.3 2 0 0 2 2 2 2 Putative Phosphatase Gpr1_Fun34_YaaH PF01184.19 CCD24434.1 - 2e-94 315.0 16.9 2.3e-94 314.8 16.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2721 PF11026.8 CCD24434.1 - 1.4 8.9 12.6 0.33 10.8 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Flo11 PF10182.9 CCD24435.1 - 2.4e-69 232.2 4.6 4.9e-69 231.2 4.6 1.6 1 0 0 1 1 1 1 Flo11 domain RVT_2 PF07727.14 CCD24436.1 - 3.4e-06 26.9 0.0 6.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_44 PF12891.7 CCD24436.1 - 0.0058 16.6 0.1 2 8.3 0.0 2.2 2 0 0 2 2 2 2 Glycoside hydrolase family 44 PRA1 PF03208.19 CCD24437.1 - 2e-37 128.0 1.6 2.5e-37 127.7 1.6 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF2207 PF09972.9 CCD24437.1 - 0.37 9.5 3.3 0.49 9.1 3.3 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_M1 PF01433.20 CCD24438.1 - 6.2e-49 166.5 2.8 1e-48 165.8 2.8 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CCD24438.1 - 2.6e-33 114.5 0.2 8.4e-33 112.8 0.0 2.0 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CCD24438.1 - 4.1e-28 98.8 0.0 6.7e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 CCD24438.1 - 0.049 13.3 0.1 0.27 10.9 0.1 2.1 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M64 PF09471.10 CCD24438.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 IgA Peptidase M64 Peptidase_M61 PF05299.12 CCD24438.1 - 0.23 11.9 1.5 4.8 7.6 1.4 2.4 1 1 0 1 1 1 0 M61 glycyl aminopeptidase ALG11_N PF15924.5 CCD24440.1 - 4.3e-81 271.9 2.4 3.2e-80 269.1 0.9 2.2 2 0 0 2 2 2 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CCD24440.1 - 2.3e-14 53.3 0.0 4.2e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCD24440.1 - 0.0003 20.8 0.0 0.00054 20.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CCD24440.1 - 0.00081 19.8 0.0 0.0024 18.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF2220 PF09983.9 CCD24440.1 - 0.0026 17.1 0.1 0.0051 16.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) DUF2399 PF09664.10 CCD24440.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) Arm PF00514.23 CCD24441.1 - 2.3e-68 224.3 26.3 8.9e-12 44.6 0.0 10.6 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CCD24441.1 - 2.1e-18 66.4 13.5 0.0004 20.8 0.1 8.0 6 2 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 CCD24441.1 - 2.3e-16 59.9 4.9 0.00091 19.6 0.0 7.2 4 2 4 8 8 8 4 HEAT repeats Adaptin_N PF01602.20 CCD24441.1 - 1.4e-11 43.7 12.5 6.7e-08 31.5 2.3 2.7 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 CCD24441.1 - 1.1e-10 40.4 4.2 7.9e-09 34.2 0.3 2.9 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) HEAT PF02985.22 CCD24441.1 - 2.2e-10 39.8 24.1 0.14 12.4 0.0 9.6 11 0 0 11 11 9 3 HEAT repeat Arm_2 PF04826.13 CCD24441.1 - 2.5e-08 33.7 11.0 0.00015 21.4 3.9 3.9 2 1 2 4 4 4 3 Armadillo-like V-ATPase_H_N PF03224.14 CCD24441.1 - 1.7e-05 24.3 5.5 0.00057 19.3 1.0 3.5 1 1 2 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 CCD24441.1 - 1.9e-05 24.7 5.2 0.39 10.8 0.3 5.4 3 2 3 6 6 6 2 V-ATPase subunit H Cnd1 PF12717.7 CCD24441.1 - 5.7e-05 23.2 13.3 0.18 11.9 0.2 5.2 2 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 CCD24441.1 - 0.00018 21.2 0.2 0.026 14.1 0.0 3.1 3 0 0 3 3 3 1 Tti2 family Vac14_Fab1_bd PF12755.7 CCD24441.1 - 0.00023 21.7 1.0 0.99 10.0 0.0 3.7 3 1 0 3 3 2 2 Vacuolar 14 Fab1-binding region DUF3361 PF11841.8 CCD24441.1 - 0.0003 20.8 8.5 0.053 13.5 0.3 4.3 2 1 1 4 4 4 1 Domain of unknown function (DUF3361) RasGEF_N_2 PF14663.6 CCD24441.1 - 0.04 14.3 4.2 33 4.9 0.0 4.7 3 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CLASP_N PF12348.8 CCD24441.1 - 0.43 10.1 4.2 6.4 6.3 0.1 3.3 2 1 1 3 3 3 0 CLASP N terminal YjeF_N PF03853.15 CCD24442.1 - 4.4e-16 59.2 0.0 9e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 CCD24442.1 - 2.5e-06 28.3 12.0 2.5e-06 28.3 12.0 4.0 4 0 0 4 4 4 1 FDF domain eRF1_2 PF03464.15 CCD24443.1 - 7.4e-29 100.7 0.1 1.6e-28 99.7 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CCD24443.1 - 1.4e-23 83.5 0.1 4.1e-23 82.0 0.1 1.8 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CCD24443.1 - 6.2e-21 74.7 0.1 9.7e-21 74.1 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 1 Septin PF00735.18 CCD24444.1 - 4e-105 351.1 2.8 4.8e-105 350.9 2.8 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CCD24444.1 - 3.4e-10 40.0 0.2 7.4e-10 38.9 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCD24444.1 - 8e-08 32.4 1.1 4.9e-07 29.8 0.2 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CCD24444.1 - 1.8e-06 27.6 2.4 4e-05 23.2 0.7 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CCD24444.1 - 2.7e-06 27.5 1.5 0.034 14.2 0.1 2.6 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 CCD24444.1 - 6.8e-06 25.6 0.6 1.7e-05 24.2 0.6 1.8 1 1 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 CCD24444.1 - 0.0014 19.0 0.0 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 CCD24444.1 - 0.0036 16.5 0.0 0.006 15.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 CCD24444.1 - 0.004 17.4 0.1 0.0087 16.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 CCD24444.1 - 0.0042 16.5 0.0 0.0088 15.4 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family CLP1_P PF16575.5 CCD24444.1 - 0.0062 16.4 0.3 0.059 13.2 0.0 2.2 1 1 1 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 CCD24444.1 - 0.014 15.5 0.5 0.041 13.9 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CCD24444.1 - 0.015 15.0 0.9 0.031 14.0 0.3 1.9 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CCD24444.1 - 0.015 15.8 2.7 0.033 14.7 2.7 1.9 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 CCD24444.1 - 0.017 14.6 0.1 0.033 13.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 CCD24444.1 - 0.021 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 CCD24444.1 - 0.024 14.0 1.7 0.41 10.0 1.7 2.2 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 CCD24444.1 - 0.025 14.7 0.0 0.1 12.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 CCD24444.1 - 0.036 14.3 0.1 0.082 13.1 0.1 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 CCD24444.1 - 0.06 13.1 0.4 1.5 8.5 0.2 2.7 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 CCD24444.1 - 0.096 12.2 2.4 1.5 8.4 1.0 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B MeaB PF03308.16 CCD24444.1 - 0.21 10.6 0.4 0.37 9.7 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MTS PF05175.14 CCD24445.1 - 2.4e-08 33.7 0.0 4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CCD24445.1 - 7e-07 29.2 0.0 9.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCD24445.1 - 0.0011 19.6 0.0 0.0017 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 CCD24445.1 - 0.0013 18.3 0.1 0.002 17.6 0.1 1.3 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Cons_hypoth95 PF03602.15 CCD24445.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 CCD24445.1 - 0.0024 17.6 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 CCD24445.1 - 0.005 16.2 0.0 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase TRM PF02005.16 CCD24445.1 - 0.056 12.6 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase CheR PF01739.18 CCD24445.1 - 0.14 11.6 1.2 2.4 7.6 0.3 2.5 1 1 1 3 3 3 0 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.12 CCD24445.1 - 0.17 12.6 0.0 0.32 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FMN_red PF03358.15 CCD24446.1 - 3.4e-08 33.4 0.0 5.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 CCD24446.1 - 0.0007 19.8 0.5 0.0041 17.3 0.1 2.4 2 1 0 2 2 2 1 Flavodoxin Flavodoxin_2 PF02525.17 CCD24446.1 - 0.073 12.8 0.8 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Flavodoxin-like fold EBP50_C PF09007.11 CCD24447.1 - 0.43 11.6 3.5 0.8 10.7 3.5 1.4 1 0 0 1 1 1 0 EBP50, C-terminal Myc_N PF01056.18 CCD24448.1 - 0.61 9.9 11.4 0.97 9.3 11.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region AF-4 PF05110.13 CCD24448.1 - 1.1 7.3 15.3 1.3 7.0 15.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Nop14 PF04147.12 CCD24448.1 - 1.1 7.4 18.5 1.5 7.0 18.5 1.1 1 0 0 1 1 1 0 Nop14-like family Hamartin PF04388.12 CCD24448.1 - 1.3 7.6 8.6 1.8 7.1 8.6 1.2 1 0 0 1 1 1 0 Hamartin protein TMEM51 PF15345.6 CCD24448.1 - 5.6 6.7 7.1 8.4 6.2 7.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 CN_hydrolase PF00795.22 CCD24449.1 - 4.2e-50 170.5 0.0 4.7e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GST_N_2 PF13409.6 CCD24450.1 - 3.1e-18 65.8 0.0 1.5e-17 63.7 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CCD24450.1 - 6.6e-10 38.9 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CCD24450.1 - 0.0029 18.0 0.0 1.1 9.7 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Gsf2 PF11055.8 CCD24451.1 - 5.7e-176 584.8 0.8 6.6e-176 584.6 0.8 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 CPSF_A PF03178.15 CCD24452.1 - 3.7e-48 164.5 1.4 3.4e-47 161.3 0.9 2.4 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 CCD24452.1 - 2.2e-47 161.8 23.0 2.2e-47 161.8 23.0 3.0 3 0 0 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Suc_Fer-like PF06999.12 CCD24453.1 - 6.7e-37 127.3 0.0 9.7e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like GST_N PF02798.20 CCD24453.1 - 0.091 13.1 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain gp32 PF08804.10 CCD24453.1 - 0.58 10.2 5.5 0.067 13.2 0.9 1.8 2 0 0 2 2 2 0 gp32 DNA binding protein like GFO_IDH_MocA PF01408.22 CCD24454.1 - 7.2e-08 33.3 0.0 1e-07 32.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CCD24454.1 - 0.14 12.2 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain SUR7 PF06687.12 CCD24455.1 - 8.3e-39 133.4 13.5 1.2e-38 132.9 13.5 1.2 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 CCD24455.1 - 0.0011 18.9 6.0 0.0016 18.4 6.0 1.3 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF805 PF05656.14 CCD24455.1 - 1.6 9.1 10.5 0.16 12.4 5.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF2614 PF11023.8 CCD24455.1 - 3.5 7.8 7.2 15 5.7 6.2 2.1 2 0 0 2 2 2 0 Zinc-ribbon containing domain DUF2207 PF09972.9 CCD24455.1 - 6.3 5.4 9.5 2.3 6.9 6.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Thymidylate_kin PF02223.17 CCD24456.1 - 2.2e-44 151.4 0.1 2.5e-44 151.2 0.1 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 CCD24456.1 - 0.018 14.5 1.3 0.2 11.1 1.3 2.3 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 CCD24456.1 - 0.098 13.2 0.0 0.24 12.0 0.0 1.7 1 1 1 2 2 2 0 AAA domain Clat_adaptor_s PF01217.20 CCD24457.1 - 7.7e-49 165.3 3.6 1.1e-47 161.6 3.6 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain AAA PF00004.29 CCD24458.1 - 3.7e-51 173.0 0.0 1.4e-43 148.5 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 CCD24458.1 - 1e-20 73.9 0.2 2.9e-20 72.5 0.2 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 CCD24458.1 - 1.7e-08 34.2 0.0 6.6e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 CCD24458.1 - 5e-08 33.5 0.1 0.025 14.9 0.0 3.6 2 2 1 3 3 3 2 AAA ATPase domain NACHT PF05729.12 CCD24458.1 - 1.9e-06 27.9 0.3 0.075 12.9 0.0 3.8 3 1 0 3 3 3 2 NACHT domain AAA_14 PF13173.6 CCD24458.1 - 2.4e-06 27.6 0.3 0.063 13.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain TIP49 PF06068.13 CCD24458.1 - 5.2e-05 22.6 0.7 0.056 12.6 0.0 3.3 3 1 0 3 3 3 1 TIP49 P-loop domain RuvB_N PF05496.12 CCD24458.1 - 0.00023 20.9 0.0 0.0034 17.1 0.0 2.8 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCD24458.1 - 0.00029 21.1 3.2 1.3 9.3 0.1 4.6 3 2 1 4 4 4 1 AAA domain AAA_18 PF13238.6 CCD24458.1 - 0.0007 20.1 7.6 0.063 13.8 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 CCD24458.1 - 0.00081 19.6 0.0 0.042 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CCD24458.1 - 0.00086 19.1 0.1 0.71 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CCD24458.1 - 0.0011 18.3 0.0 1.5 8.0 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 CCD24458.1 - 0.0011 18.9 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 CCD24458.1 - 0.0023 18.0 0.0 0.45 10.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CCD24458.1 - 0.0024 18.0 0.0 0.0084 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 CCD24458.1 - 0.0026 18.1 0.0 0.34 11.3 0.0 3.2 2 0 0 2 2 2 1 RNA helicase Viral_helicase1 PF01443.18 CCD24458.1 - 0.0048 16.7 0.0 0.74 9.5 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 CCD24458.1 - 0.0056 16.3 0.1 0.68 9.5 0.1 3.0 2 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CCD24458.1 - 0.0079 16.0 0.0 0.25 11.0 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.6 CCD24458.1 - 0.015 15.8 2.4 0.28 11.6 0.0 3.1 3 1 0 3 3 2 0 AAA domain ABC_tran PF00005.27 CCD24458.1 - 0.018 15.5 0.2 9.8 6.7 0.0 3.5 3 0 0 3 3 3 0 ABC transporter NB-ARC PF00931.22 CCD24458.1 - 0.031 13.5 2.3 3.2 6.9 0.0 3.1 3 0 0 3 3 2 0 NB-ARC domain NTPase_1 PF03266.15 CCD24458.1 - 0.058 13.3 0.1 4.4 7.2 0.0 2.8 3 0 0 3 3 2 0 NTPase AAA_28 PF13521.6 CCD24458.1 - 0.066 13.5 0.0 0.92 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CCD24458.1 - 0.074 12.3 0.1 2.8 7.1 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin Skp1 PF01466.19 CCD24458.1 - 0.11 12.7 0.2 0.52 10.5 0.1 2.2 2 0 0 2 2 1 0 Skp1 family, dimerisation domain AAA_3 PF07726.11 CCD24458.1 - 0.12 12.2 0.0 0.34 10.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CCD24458.1 - 0.13 11.6 0.0 0.6 9.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 CCD24458.1 - 0.14 11.2 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP_bind_1 PF03029.17 CCD24458.1 - 2 8.1 4.7 0.57 9.9 0.1 2.5 3 1 1 4 4 3 0 Conserved hypothetical ATP binding protein Pkinase PF00069.25 CCD24459.1 - 2.4e-37 128.7 0.0 4e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24459.1 - 1.3e-15 57.5 0.0 2.1e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CCD24459.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCD24459.1 - 0.07 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like ACDC PF14733.6 CCD24459.1 - 0.085 13.2 0.7 2 8.8 0.1 2.8 2 0 0 2 2 2 0 AP2-coincident C-terminal LicD PF04991.13 CCD24460.1 - 8.2e-54 183.1 2.5 8.2e-54 183.1 2.5 2.7 3 0 0 3 3 3 1 LicD family FAT PF02259.23 CCD24461.1 - 4.4e-124 414.2 0.0 1.3e-123 412.6 0.0 1.9 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 CCD24461.1 - 6.9e-71 239.0 0.1 1.7e-70 237.7 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 CCD24461.1 - 4.3e-62 208.8 14.6 2.1e-61 206.5 0.1 5.1 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CCD24461.1 - 3e-42 143.0 3.4 3.5e-42 142.8 0.7 2.7 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 CCD24461.1 - 3.2e-16 58.8 1.1 1.1e-15 57.2 1.1 2.0 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 CCD24461.1 - 1.6e-08 34.1 2.0 0.03 14.6 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 CCD24461.1 - 1.5e-07 31.7 0.0 0.17 12.3 0.0 7.3 5 2 1 7 7 7 1 HEAT repeats HEAT_EZ PF13513.6 CCD24461.1 - 0.00018 21.9 8.4 0.23 12.0 0.0 8.5 10 1 2 12 12 10 2 HEAT-like repeat TPR_19 PF14559.6 CCD24461.1 - 0.024 15.2 0.0 0.93 10.0 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.7 CCD24461.1 - 0.16 12.6 7.8 4.9 7.8 0.0 5.5 6 1 1 7 7 7 0 Vacuolar 14 Fab1-binding region DUF3437 PF11919.8 CCD24461.1 - 0.16 11.9 1.4 1.5 8.8 0.0 3.4 5 0 0 5 5 3 0 Domain of unknown function (DUF3437) Sec7_N PF12783.7 CCD24461.1 - 0.17 11.8 16.9 1.5 8.7 2.4 5.5 3 1 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CLASP_N PF12348.8 CCD24461.1 - 1.2 8.7 6.6 1.2 8.6 0.0 4.2 5 1 1 6 6 6 0 CLASP N terminal Xpo1 PF08389.12 CCD24462.1 - 2.4e-36 125.0 10.1 1.5e-35 122.4 0.7 4.3 4 1 1 5 5 5 2 Exportin 1-like protein IBN_N PF03810.19 CCD24462.1 - 0.056 13.4 3.6 0.66 9.9 0.3 3.4 3 0 0 3 3 3 0 Importin-beta N-terminal domain MOR2-PAG1_C PF14225.6 CCD24462.1 - 0.27 11.1 3.6 1.4 8.7 0.1 3.0 3 0 0 3 3 3 0 Cell morphogenesis C-terminal Ham1p_like PF01725.16 CCD24463.1 - 1.3e-50 171.9 0.0 1.5e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family HEAT_2 PF13646.6 CCD24464.1 - 7.6e-36 122.4 2.2 1.2e-17 64.0 0.0 3.3 2 2 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 CCD24464.1 - 1e-20 72.2 5.2 1.1e-05 25.7 0.0 6.7 7 1 0 7 7 7 3 PBS lyase HEAT-like repeat HEAT PF02985.22 CCD24464.1 - 3.4e-13 48.6 3.1 0.1 12.9 0.0 6.0 6 0 0 6 6 6 4 HEAT repeat Cnd1 PF12717.7 CCD24464.1 - 1.9e-05 24.8 0.1 0.22 11.5 0.0 4.2 2 1 4 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CCD24464.1 - 2.3e-05 24.8 2.0 1.5 9.4 0.2 5.2 4 2 1 5 5 5 3 HEAT-like repeat Adaptin_N PF01602.20 CCD24464.1 - 0.076 11.6 0.3 3.4 6.1 0.0 2.8 2 1 0 3 3 3 0 Adaptin N terminal region ATP_bind_1 PF03029.17 CCD24465.1 - 3.6e-81 272.5 0.2 5e-81 272.0 0.2 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CCD24465.1 - 1e-07 31.7 0.3 2.1e-06 27.4 0.2 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CCD24465.1 - 2.3e-05 24.4 0.0 0.0032 17.5 0.0 3.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 CCD24465.1 - 5.9e-05 23.3 0.0 0.00013 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CCD24465.1 - 8.9e-05 22.3 0.1 0.00027 20.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 CCD24465.1 - 0.0003 20.6 0.1 0.014 15.1 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 CCD24465.1 - 0.00049 19.2 0.0 0.44 9.5 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 CCD24465.1 - 0.00062 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain CLP1_P PF16575.5 CCD24465.1 - 0.00076 19.3 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 CCD24465.1 - 0.00092 18.9 0.0 0.048 13.3 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain FeoB_N PF02421.18 CCD24465.1 - 0.0016 18.0 0.1 0.034 13.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CCD24465.1 - 0.0021 18.0 0.2 2.7 7.9 0.2 3.5 2 1 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 CCD24465.1 - 0.0028 17.1 0.4 0.31 10.5 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CCD24465.1 - 0.0037 17.5 0.0 0.014 15.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 CCD24465.1 - 0.0072 15.9 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 CCD24465.1 - 0.0095 16.3 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 CCD24465.1 - 0.01 16.0 0.1 0.67 10.2 0.0 2.7 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 CCD24465.1 - 0.01 16.4 0.6 0.034 14.7 0.0 2.2 2 1 1 3 3 2 0 AAA domain PRK PF00485.18 CCD24465.1 - 0.014 15.1 0.0 0.049 13.4 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 CCD24465.1 - 0.023 13.9 0.0 0.058 12.6 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 CCD24465.1 - 0.026 14.3 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 CCD24465.1 - 0.027 13.9 1.8 1.1 8.7 0.0 3.1 3 1 0 3 3 3 0 ADP-ribosylation factor family DUF87 PF01935.17 CCD24465.1 - 0.044 13.9 0.4 5.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain KTI12 PF08433.10 CCD24465.1 - 0.046 13.2 0.0 0.088 12.2 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 cobW PF02492.19 CCD24465.1 - 0.054 13.1 0.3 0.52 9.9 0.3 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 CCD24465.1 - 0.058 13.5 2.6 9.8 6.2 0.2 3.2 2 1 0 2 2 2 0 Dynamin family Septin PF00735.18 CCD24465.1 - 0.059 12.6 0.3 0.42 9.9 0.3 2.1 1 1 0 1 1 1 0 Septin AAA_31 PF13614.6 CCD24465.1 - 0.085 12.8 0.1 1.8 8.4 0.1 2.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CCD24465.1 - 0.087 12.7 0.1 2.7 7.9 0.1 2.2 2 0 0 2 2 2 0 NTPase ATP-synt_E PF05680.12 CCD24465.1 - 2.8 8.3 5.3 0.39 11.1 0.9 1.8 2 0 0 2 2 1 0 ATP synthase E chain EMC3_TMCO1 PF01956.16 CCD24466.1 - 2.1e-55 187.1 2.3 2.6e-55 186.7 2.3 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like ABC_membrane PF00664.23 CCD24468.1 - 4.5e-105 351.2 38.8 5.6e-55 186.9 16.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CCD24468.1 - 2.9e-64 215.7 0.8 2.4e-31 109.1 0.0 3.0 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CCD24468.1 - 3.5e-16 59.3 8.8 2.5e-06 27.1 0.0 5.1 3 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CCD24468.1 - 3.4e-11 43.5 0.3 1e-05 25.4 0.0 3.1 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CCD24468.1 - 1.3e-09 38.4 1.2 0.0016 18.7 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CCD24468.1 - 5e-09 36.8 0.1 0.0064 16.9 0.0 3.4 3 2 0 3 3 2 2 AAA ATPase domain RNA_helicase PF00910.22 CCD24468.1 - 2.2e-07 31.2 0.1 0.011 16.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase ABC_ATPase PF09818.9 CCD24468.1 - 2.3e-07 30.0 1.0 0.018 13.8 0.0 3.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 CCD24468.1 - 3.2e-07 30.0 8.5 0.00098 18.8 0.2 3.4 4 0 0 4 4 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCD24468.1 - 3.3e-07 30.4 0.2 0.014 15.3 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 CCD24468.1 - 1.9e-06 28.1 3.0 0.13 12.4 0.0 3.7 3 0 0 3 3 3 2 Helicase HerA, central domain MMR_HSR1 PF01926.23 CCD24468.1 - 9.4e-06 25.7 0.4 0.2 11.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 CCD24468.1 - 1.4e-05 24.9 0.1 0.19 11.4 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 CCD24468.1 - 3.7e-05 23.7 0.0 0.64 10.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) NACHT PF05729.12 CCD24468.1 - 4.6e-05 23.4 1.8 2.6 7.9 0.0 3.7 3 0 0 3 3 3 2 NACHT domain Zeta_toxin PF06414.12 CCD24468.1 - 0.00011 21.6 0.0 0.48 9.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.6 CCD24468.1 - 0.00012 22.6 0.1 0.44 11.1 0.0 3.4 3 0 0 3 3 2 1 AAA domain Ploopntkinase3 PF18751.1 CCD24468.1 - 0.00016 21.7 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 CCD24468.1 - 0.00029 20.6 1.3 0.36 10.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain Septin PF00735.18 CCD24468.1 - 0.00054 19.3 0.4 0.14 11.4 0.0 2.5 2 0 0 2 2 2 1 Septin AAA_23 PF13476.6 CCD24468.1 - 0.00055 20.5 11.7 0.038 14.5 0.1 3.4 4 0 0 4 4 2 2 AAA domain Sigma54_activat PF00158.26 CCD24468.1 - 0.0008 19.2 0.0 0.78 9.4 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain PRK PF00485.18 CCD24468.1 - 0.00083 19.1 0.0 0.088 12.5 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family T2SSE PF00437.20 CCD24468.1 - 0.0011 18.1 1.3 0.54 9.3 0.1 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein DUF3987 PF13148.6 CCD24468.1 - 0.0017 17.5 0.0 0.55 9.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) APS_kinase PF01583.20 CCD24468.1 - 0.0019 18.1 0.1 2.1 8.2 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_14 PF13173.6 CCD24468.1 - 0.0028 17.7 7.7 0.27 11.3 0.0 5.2 6 0 0 6 6 4 1 AAA domain AAA_33 PF13671.6 CCD24468.1 - 0.0029 17.8 0.2 0.76 9.9 0.2 2.7 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CCD24468.1 - 0.0044 16.5 2.3 1 8.9 0.1 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region Roc PF08477.13 CCD24468.1 - 0.0053 17.0 0.7 5.4 7.3 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase KAP_NTPase PF07693.14 CCD24468.1 - 0.0055 16.0 0.0 0.35 10.0 0.0 2.5 2 0 0 2 2 2 1 KAP family P-loop domain NB-ARC PF00931.22 CCD24468.1 - 0.011 14.9 0.9 3 6.9 0.1 3.0 3 0 0 3 3 3 0 NB-ARC domain ATP_bind_1 PF03029.17 CCD24468.1 - 0.013 15.3 0.7 12 5.6 0.0 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.6 CCD24468.1 - 0.016 15.0 13.7 0.82 9.4 0.1 4.3 4 1 1 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 CCD24468.1 - 0.017 14.8 0.0 0.78 9.4 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 CCD24468.1 - 0.017 14.3 0.0 0.97 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MobB PF03205.14 CCD24468.1 - 0.039 13.8 0.8 5.8 6.8 0.1 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.7 CCD24468.1 - 0.046 12.6 0.1 4.6 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.18 CCD24468.1 - 0.091 12.1 1.1 15 4.8 0.1 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family ATPase PF06745.13 CCD24468.1 - 0.093 12.1 0.4 17 4.6 0.1 2.8 2 0 0 2 2 2 0 KaiC CbiA PF01656.23 CCD24468.1 - 0.18 11.9 0.2 12 6.0 0.1 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DPM2 PF07297.12 CCD24469.1 - 1.8e-08 34.5 6.7 1.9e-08 34.5 6.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 CCD24469.1 - 0.51 10.3 4.0 0.63 10.0 4.0 1.2 1 0 0 1 1 1 0 PIG-P Ribosomal_L1 PF00687.21 CCD24470.1 - 2.7e-35 122.0 7.1 5.8e-35 120.9 7.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Porphyrn_cat_1 PF18206.1 CCD24470.1 - 0.014 16.0 1.0 0.21 12.2 0.1 2.6 2 0 0 2 2 2 0 Porphyranase catalytic subdomain 1 HalX PF08663.10 CCD24470.1 - 0.086 13.2 1.8 0.21 11.9 1.8 1.6 1 0 0 1 1 1 0 HalX domain ApbA PF02558.16 CCD24471.1 - 3.7e-28 98.1 0.0 5.5e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 CCD24471.1 - 9.4e-27 93.7 0.0 1.5e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal F420_oxidored PF03807.17 CCD24471.1 - 0.16 12.6 0.0 0.35 11.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent BBS2_C PF14782.6 CCD24471.1 - 0.41 9.4 3.1 0.26 10.0 1.3 1.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal GCR1_C PF12550.8 CCD24472.1 - 3.1e-10 40.2 1.5 3.1e-10 40.2 1.5 2.2 2 1 0 2 2 2 1 Transcriptional activator of glycolytic enzymes MerR_1 PF13411.6 CCD24472.1 - 0.035 14.2 0.5 0.083 13.0 0.5 1.6 1 0 0 1 1 1 0 MerR HTH family regulatory protein Fungal_TACC PF12709.7 CCD24472.1 - 7 7.2 9.1 1.3 9.5 3.2 2.6 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins MatE PF01554.18 CCD24473.1 - 4.2e-69 231.3 28.4 3.8e-41 140.4 9.6 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 CCD24473.1 - 0.00023 21.2 4.2 0.00023 21.2 4.2 3.6 3 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Aldo_ket_red PF00248.21 CCD24474.1 - 1.9e-41 142.2 0.0 2.8e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family TT1725 PF18324.1 CCD24474.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Hypothetical protein TT1725 PIF1 PF05970.14 CCD24475.1 - 2.5e-51 175.0 3.7 1.1e-48 166.2 3.7 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CCD24475.1 - 1.5e-20 73.8 0.0 1.9e-19 70.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CCD24475.1 - 2e-10 41.2 0.1 3.8e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 CCD24475.1 - 9.2e-07 27.2 0.7 0.00061 17.9 0.0 2.3 2 0 0 2 2 2 2 Helicase T2SSE PF00437.20 CCD24475.1 - 6.8e-05 22.1 2.0 0.00014 21.0 2.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 CCD24475.1 - 0.00013 22.2 0.0 0.00044 20.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CCD24475.1 - 0.00046 19.7 2.0 0.00055 19.5 0.1 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region SH3_13 PF18335.1 CCD24475.1 - 0.0031 17.3 0.0 0.0097 15.7 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain AAA PF00004.29 CCD24475.1 - 0.0052 17.2 0.1 0.019 15.4 0.1 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CCD24475.1 - 0.011 15.8 0.0 0.057 13.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CCD24475.1 - 0.018 14.3 0.3 0.048 12.9 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CCD24475.1 - 0.026 14.0 0.0 0.066 12.7 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.21 CCD24475.1 - 0.039 13.3 0.1 0.082 12.3 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Helicase_RecD PF05127.14 CCD24475.1 - 0.053 13.4 0.5 0.23 11.3 0.5 2.1 1 1 0 1 1 1 0 Helicase UvrD_C_2 PF13538.6 CCD24475.1 - 0.095 12.6 0.3 0.49 10.3 0.3 2.1 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain RNA_helicase PF00910.22 CCD24475.1 - 0.26 11.7 1.4 1.7 9.1 0.3 2.9 2 1 0 2 2 2 0 RNA helicase Pkinase PF00069.25 CCD24476.1 - 5.3e-64 216.1 0.3 1.1e-63 215.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24476.1 - 3.8e-31 108.3 0.4 6.7e-31 107.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCD24476.1 - 0.0049 15.9 0.8 0.016 14.2 0.1 2.1 2 1 0 2 2 2 1 Haspin like kinase domain Spt20 PF12090.8 CCD24476.1 - 0.007 16.0 17.8 0.011 15.4 17.8 1.2 1 0 0 1 1 1 1 Spt20 family DUF4230 PF14014.6 CCD24476.1 - 0.0072 16.6 5.1 0.02 15.2 5.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4230) APH PF01636.23 CCD24476.1 - 0.0079 16.1 3.3 0.17 11.8 0.1 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family WD40 PF00400.32 CCD24476.1 - 0.044 14.7 0.0 0.16 12.9 0.0 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat PhzC-PhzF PF02567.16 CCD24477.1 - 3.3e-68 230.2 0.0 3.8e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Elf1 PF05129.13 CCD24478.1 - 1e-29 102.4 1.1 1.3e-29 102.0 1.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Ribosomal_L37ae PF01780.19 CCD24478.1 - 0.0049 16.9 1.3 0.0082 16.2 1.3 1.3 1 0 0 1 1 1 1 Ribosomal L37ae protein family Vps36-NZF-N PF16988.5 CCD24478.1 - 0.02 14.3 2.2 0.033 13.6 2.2 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 CCD24478.1 - 0.14 12.3 6.4 0.91 9.6 2.0 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.7 CCD24478.1 - 0.5 10.7 3.6 2.4 8.5 0.5 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) COX5A PF02284.16 CCD24479.1 - 1e-39 134.7 1.7 1.3e-39 134.4 1.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Nterm_IS4 PF13006.7 CCD24479.1 - 0.081 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal Nramp PF01566.18 CCD24480.1 - 5.1e-93 311.9 11.8 8.3e-93 311.2 11.8 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein FSH1 PF03959.13 CCD24481.1 - 4.2e-63 212.8 0.0 4.8e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 CCD24481.1 - 0.004 16.8 0.0 0.23 11.1 0.0 2.8 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CCD24481.1 - 0.022 14.6 0.8 1.2 8.9 0.6 2.7 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.18 CCD24481.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family MFS_1 PF07690.16 CCD24482.1 - 6.4e-35 120.7 32.2 6.4e-35 120.7 32.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCD24482.1 - 0.00033 19.7 40.8 0.00099 18.1 40.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Inositol_P PF00459.25 CCD24483.1 - 1.6e-68 231.2 0.0 1.8e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF327 PF03885.13 CCD24483.1 - 0.072 13.1 0.4 0.11 12.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF327) DUF4637 PF15470.6 CCD24486.1 - 1.9e-05 24.4 0.0 3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) Glyco_hydro_42 PF02449.15 CCD24486.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase HSP70 PF00012.20 CCD24486.1 - 0.55 8.3 7.2 0.79 7.8 7.2 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF2722 PF10846.8 CCD24486.1 - 0.69 8.8 5.5 0.94 8.3 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RRN3 PF05327.11 CCD24486.1 - 2.6 6.5 7.1 3.8 5.9 6.7 1.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 IGR PF09597.10 CCD24487.1 - 2e-23 82.2 0.2 3.3e-23 81.5 0.2 1.4 1 0 0 1 1 1 1 IGR protein motif SAM_2 PF07647.17 CCD24487.1 - 0.0098 16.0 0.0 0.019 15.0 0.0 1.5 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) Med6 PF04934.14 CCD24488.1 - 6.5e-53 178.1 0.1 9.8e-53 177.5 0.1 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component CoA_trans PF01144.23 CCD24488.1 - 0.042 13.2 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase MFS_1 PF07690.16 CCD24489.1 - 1.4e-31 109.7 23.2 1.4e-31 109.7 23.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 CCD24489.1 - 3.4e-08 33.2 1.6 3.4e-08 33.2 1.6 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB BrkDBD PF09607.10 CCD24489.1 - 0.1 12.4 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Brinker DNA-binding domain ERGIC_N PF13850.6 CCD24489.1 - 0.11 12.8 0.1 28 5.2 0.0 2.9 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pro_isomerase PF00160.21 CCD24490.1 - 1.6e-45 155.2 0.1 2e-45 154.9 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Zn_clus PF00172.18 CCD24491.1 - 1.4e-07 31.5 7.2 2.2e-07 30.9 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPN1_RPN2_N PF17781.1 CCD24493.1 - 4.5e-113 377.7 0.3 4.5e-113 377.7 0.3 1.8 3 0 0 3 3 3 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CCD24493.1 - 4.4e-29 100.3 0.0 8.3e-29 99.4 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CCD24493.1 - 5.1e-25 86.6 13.9 2e-06 28.0 0.2 8.4 7 0 0 7 7 7 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CCD24493.1 - 0.00054 20.3 0.6 2.2 8.7 0.0 4.5 5 0 0 5 5 5 2 HEAT repeats Macoilin PF09726.9 CCD24493.1 - 4.1 5.8 21.7 0.01 14.5 9.2 2.1 2 0 0 2 2 2 0 Macoilin family ATP-synt_C PF00137.21 CCD24494.1 - 4.6e-23 81.3 38.9 2.8e-16 59.6 13.3 2.5 3 0 0 3 3 3 2 ATP synthase subunit C ATP-synt_8 PF00895.20 CCD24494.1 - 1.6 9.2 3.7 11 6.5 0.8 2.4 2 0 0 2 2 2 0 ATP synthase protein 8 GHMP_kinases_N PF00288.26 CCD24495.1 - 1e-09 38.5 0.0 1.9e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CCD24495.1 - 0.00016 22.0 0.0 0.00044 20.5 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Peptidase_M16_C PF05193.21 CCD24496.1 - 1e-43 149.5 0.0 3.9e-43 147.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CCD24496.1 - 4.9e-41 140.2 0.0 1.7e-40 138.4 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) AAA_5 PF07728.14 CCD24496.1 - 0.0055 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Myosin_head PF00063.21 CCD24497.1 - 3.2e-272 904.7 14.3 3.2e-272 904.7 14.3 3.1 3 0 0 3 3 3 1 Myosin head (motor domain) AAA_7 PF12775.7 CCD24497.1 - 0.00025 20.6 1.0 0.0015 18.1 0.5 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 CCD24497.1 - 0.0047 16.9 0.1 0.018 15.0 0.1 2.0 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE HALZ PF02183.18 CCD24497.1 - 0.0073 16.5 0.4 0.0073 16.5 0.4 10.6 10 2 1 11 11 11 1 Homeobox associated leucine zipper AAA_5 PF07728.14 CCD24497.1 - 0.054 13.5 1.7 1.5 8.8 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CCD24497.1 - 0.2 12.1 1.3 7.1 7.1 0.1 3.5 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 CCD24497.1 - 0.26 11.7 0.0 0.26 11.7 0.0 3.7 3 2 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 CCD24497.1 - 7 6.9 9.9 0.3 11.3 0.1 3.8 3 1 0 3 3 3 0 AAA domain Ras PF00071.22 CCD24498.1 - 1.1e-25 90.1 0.9 9.5e-18 64.3 0.3 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CCD24498.1 - 1.3e-10 41.5 0.1 9e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CCD24498.1 - 0.0024 17.3 0.2 0.015 14.6 0.2 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ribosomal_S27e PF01667.17 CCD24499.1 - 3.1e-30 103.7 2.8 4e-30 103.3 2.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.21 CCD24499.1 - 0.005 17.0 0.9 0.0059 16.8 0.9 1.2 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain TF_Zn_Ribbon PF08271.12 CCD24499.1 - 0.024 14.2 4.2 0.035 13.6 4.2 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding zf-ACC PF17848.1 CCD24499.1 - 3.2 7.9 6.4 19 5.4 0.2 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain NIF PF03031.18 CCD24500.1 - 9.7e-54 181.4 0.0 2e-53 180.3 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Abhydro_lipase PF04083.16 CCD24501.1 - 2e-16 59.3 0.1 4.3e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CCD24501.1 - 2.3e-05 23.8 0.0 0.00024 20.5 0.0 2.4 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCD24501.1 - 5.8e-05 22.9 1.2 0.00011 22.0 0.0 2.0 3 0 0 3 3 3 1 alpha/beta hydrolase fold Phyto_Pns9_10 PF05878.11 CCD24501.1 - 0.006 15.8 1.4 0.0065 15.7 0.4 1.4 2 0 0 2 2 2 1 Phytoreovirus nonstructural protein Pns9/Pns10 DUF900 PF05990.12 CCD24501.1 - 0.012 15.2 0.1 0.028 13.9 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Chlorophyllase2 PF12740.7 CCD24501.1 - 0.037 12.9 0.0 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme Lipase_2 PF01674.18 CCD24501.1 - 0.077 12.5 0.0 0.29 10.6 0.0 1.9 1 1 0 1 1 1 0 Lipase (class 2) PUF PF00806.19 CCD24502.1 - 1.2e-53 175.9 19.1 5.5e-07 28.9 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Rab5ip PF07019.12 CCD24503.1 - 1.1e-21 77.2 7.5 1.3e-21 77.0 7.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF383 PF04063.14 CCD24504.1 - 2.6e-62 209.9 3.1 7.4e-62 208.4 1.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 CCD24504.1 - 1e-20 73.3 0.3 3.8e-20 71.5 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF4611 PF15387.6 CCD24504.1 - 0.11 12.7 8.6 0.27 11.5 8.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RNA_pol_3_Rpc31 PF11705.8 CCD24504.1 - 0.53 10.5 8.7 0.77 10.0 8.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 CCD24504.1 - 1.3 8.3 9.4 1.9 7.7 9.4 1.2 1 0 0 1 1 1 0 NOA36 protein Cytomega_UL84 PF06284.11 CCD24504.1 - 3.1 6.1 6.1 4.3 5.7 6.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Cwf_Cwc_15 PF04889.12 CCD24504.1 - 6 6.5 11.4 12 5.6 11.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.12 CCD24505.1 - 2.3e-05 23.2 43.6 2.3e-05 23.2 43.6 3.3 2 1 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ATP-cone PF03477.16 CCD24505.1 - 0.29 11.8 3.1 0.56 10.8 1.1 2.5 2 0 0 2 2 2 0 ATP cone domain Phage_TAC_4 PF08748.11 CCD24505.1 - 1.9 8.8 5.4 1.2 9.4 0.2 3.0 3 0 0 3 3 3 0 Phage tail assembly chaperone zf-UBR PF02207.20 CCD24506.1 - 6.2e-16 58.3 14.9 6.2e-16 58.3 14.9 2.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 CCD24506.1 - 3.6e-05 23.5 0.0 0.00012 21.8 0.0 1.9 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 CCD24506.1 - 0.0007 19.9 1.7 0.0007 19.9 1.7 3.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 CCD24506.1 - 0.0029 17.4 1.5 0.014 15.3 1.5 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CCD24506.1 - 0.0058 16.9 0.5 0.0058 16.9 0.5 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain UCR_UQCRX_QCR9 PF05365.12 CCD24507.1 - 2e-25 88.5 3.0 2.2e-25 88.3 3.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF2976 PF11190.8 CCD24507.1 - 0.014 15.2 0.2 0.015 15.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) zf-Tim10_DDP PF02953.15 CCD24508.1 - 1.6e-19 69.3 2.9 2.4e-19 68.7 2.9 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger SYCP2_ARLD PF18581.1 CCD24508.1 - 0.047 13.7 0.1 0.053 13.5 0.1 1.0 1 0 0 1 1 1 0 Synaptonemal complex 2 armadillo-repeat-like domain Ribonuc_red_sm PF00268.21 CCD24509.1 - 2.7e-84 283.0 0.3 3.4e-84 282.6 0.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Exonuc_VII_L PF02601.15 CCD24510.1 - 3.6 7.1 7.4 6.6 6.2 7.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit LsmAD PF06741.13 CCD24511.1 - 5.6e-29 100.5 0.3 5.6e-29 100.5 0.3 2.4 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 CCD24511.1 - 2.8e-15 56.2 0.3 8.9e-15 54.6 0.3 1.9 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CCD24511.1 - 0.016 15.3 0.2 0.037 14.1 0.2 1.6 1 0 0 1 1 1 0 Scd6-like Sm domain DUF1776 PF08643.10 CCD24511.1 - 0.16 11.3 0.1 0.33 10.3 0.1 1.6 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF3452 PF11934.8 CCD24511.1 - 0.92 9.1 3.3 6.3 6.4 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF3452) Tox-REase-5 PF15648.6 CCD24511.1 - 1.6 9.3 9.9 0.37 11.3 0.8 2.9 3 0 0 3 3 3 0 Restriction endonuclease fold toxin 5 AATase PF07247.12 CCD24512.1 - 3e-147 491.2 5.2 3.5e-147 491.0 5.2 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase DUF1256 PF06866.11 CCD24512.1 - 0.069 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) Condensation PF00668.20 CCD24512.1 - 0.15 10.7 0.2 5.6 5.5 0.0 2.5 3 0 0 3 3 3 0 Condensation domain SE PF08491.10 CCD24513.1 - 7.5e-118 392.5 0.0 9.7e-118 392.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 CCD24513.1 - 2.8e-14 53.1 0.0 4.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CCD24513.1 - 2e-07 31.0 0.1 4.4e-05 23.2 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 CCD24513.1 - 0.0004 20.9 0.8 0.0011 19.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CCD24513.1 - 0.00092 19.4 0.1 0.0021 18.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CCD24513.1 - 0.0016 17.8 0.5 0.0066 15.7 0.1 2.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CCD24513.1 - 0.0053 15.9 1.6 0.0088 15.2 0.7 1.7 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 CCD24513.1 - 0.0053 16.8 0.0 0.0094 16.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 CCD24513.1 - 0.0074 15.7 0.6 0.016 14.5 0.6 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CCD24513.1 - 0.0082 16.1 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 CCD24513.1 - 0.024 13.9 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DUF1331 PF07048.11 CCD24513.1 - 0.025 14.3 0.6 0.08 12.6 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) ApbA PF02558.16 CCD24513.1 - 0.051 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 CCD24513.1 - 0.13 11.8 0.4 0.47 10.0 0.1 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 CCD24513.1 - 0.14 12.4 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CBP4 PF07960.11 CCD24514.1 - 1e-54 183.9 2.3 1.2e-54 183.6 2.3 1.1 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 CCD24514.1 - 0.00053 19.8 2.8 0.00057 19.7 0.1 2.1 1 1 0 2 2 2 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 LAMTOR PF15454.6 CCD24514.1 - 0.084 13.5 0.5 0.084 13.5 0.5 2.2 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator MMR_HSR1_Xtn PF16897.5 CCD24515.1 - 7e-36 122.5 1.0 1.4e-35 121.5 1.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CCD24515.1 - 1.3e-21 76.8 0.0 2.7e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CCD24515.1 - 5.8e-20 71.1 0.0 1.2e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CCD24515.1 - 2.4e-13 49.9 0.0 4.2e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CCD24515.1 - 0.00011 22.3 0.3 0.053 13.6 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 CCD24515.1 - 0.00063 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 CCD24515.1 - 0.012 15.9 0.6 0.11 12.8 0.1 2.5 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CCD24515.1 - 0.013 15.0 0.3 0.098 12.1 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Ras PF00071.22 CCD24515.1 - 0.031 13.9 0.3 0.89 9.1 0.0 2.3 2 0 0 2 2 2 0 Ras family MCM PF00493.23 CCD24515.1 - 0.041 13.0 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 MCM P-loop domain AAA_16 PF13191.6 CCD24515.1 - 0.049 14.0 0.2 0.11 12.9 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF1178 PF06676.11 CCD24515.1 - 0.13 12.6 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) RsgA_GTPase PF03193.16 CCD24515.1 - 0.21 11.5 1.7 2.1 8.2 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase Yip1 PF04893.17 CCD24516.1 - 1.1e-12 48.0 14.3 1.5e-12 47.5 14.3 1.2 1 0 0 1 1 1 1 Yip1 domain tRNA-synt_1g PF09334.11 CCD24517.1 - 2.9e-89 299.6 0.8 1.5e-87 293.9 0.8 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CCD24517.1 - 5.9e-26 90.9 1.1 2.5e-12 45.8 0.1 3.4 1 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CCD24517.1 - 1.4e-07 31.1 0.1 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain PS_Dcarbxylase PF02666.15 CCD24518.1 - 1.9e-52 177.8 0.0 3.1e-52 177.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 CCD24518.1 - 1.5e-19 70.1 0.6 5.5e-12 45.9 0.1 3.3 3 0 0 3 3 3 2 C2 domain RRM PF10378.9 CCD24518.1 - 0.0029 17.3 2.5 0.0074 16.0 2.5 1.7 1 0 0 1 1 1 1 Putative RRM domain Ribosomal_S2 PF00318.20 CCD24519.1 - 0.74 9.0 5.8 0.79 8.9 5.8 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 PseudoU_synth_2 PF00849.22 CCD24520.1 - 6.2e-27 94.6 0.0 9.9e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase partial_CstF PF15861.5 CCD24520.1 - 0.012 15.4 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain ATP_synt_H PF05493.13 CCD24521.1 - 2.5e-20 72.7 3.6 3e-20 72.4 3.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit H MFS_2 PF13347.6 CCD24521.1 - 0.0012 17.5 0.6 0.0012 17.5 0.6 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein Halogen_Hydrol PF10112.9 CCD24521.1 - 0.026 14.5 0.3 0.026 14.5 0.3 1.0 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF5373 PF17343.2 CCD24521.1 - 0.031 14.1 0.2 0.034 14.0 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5373) Glucos_trans_II PF14264.6 CCD24521.1 - 0.041 13.2 2.2 0.043 13.2 2.2 1.0 1 0 0 1 1 1 0 Glucosyl transferase GtrII FixQ PF05545.11 CCD24521.1 - 0.15 12.0 0.6 0.15 12.0 0.6 1.7 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF1385 PF07136.11 CCD24521.1 - 0.21 10.8 2.5 0.26 10.5 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) Clathrin_lg_ch PF01086.17 CCD24523.1 - 6.8e-54 183.4 18.5 7.9e-54 183.1 18.5 1.0 1 0 0 1 1 1 1 Clathrin light chain Trs65 PF12735.7 CCD24524.1 - 1.5e-42 146.2 3.0 3.5e-42 144.9 3.0 1.7 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 DUF916 PF06030.12 CCD24524.1 - 1.6 8.8 8.5 1.9 8.5 1.8 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF916) Bot1p PF12298.8 CCD24525.1 - 5e-58 196.1 0.5 7e-58 195.6 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein DUF2316 PF10078.9 CCD24525.1 - 0.0032 17.6 0.1 0.0095 16.2 0.1 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2316) Sad1_UNC PF07738.13 CCD24526.1 - 1.5e-09 37.9 0.2 1e-07 32.0 0.2 2.5 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF4709 PF15821.5 CCD24526.1 - 1.6 9.0 8.0 9.4 6.6 1.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4709) Baculo_PEP_C PF04513.12 CCD24526.1 - 4.7 7.2 17.8 0.12 12.4 2.3 4.0 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cpn60_TCP1 PF00118.24 CCD24527.1 - 2.9e-164 547.3 4.3 3.3e-164 547.1 4.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NusA_N PF08529.11 CCD24527.1 - 0.1 12.9 0.3 0.1 12.9 0.3 2.1 2 0 0 2 2 2 0 NusA N-terminal domain DUF3683 PF12447.8 CCD24527.1 - 0.15 12.2 0.0 31 4.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) Mad3_BUB1_I PF08311.12 CCD24528.1 - 5e-30 104.0 2.1 1.3e-29 102.7 2.1 1.8 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 CCD24528.1 - 1.4e-23 82.8 1.9 3.7e-23 81.5 1.9 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 CCD24528.1 - 3.8e-18 65.8 0.0 8.3e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24528.1 - 1.4e-05 24.5 0.0 4.1e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 CCD24528.1 - 2.5e-05 24.4 3.8 3e-05 24.1 1.9 2.1 2 0 0 2 2 2 1 Putative Mad3/BUB1 like region 1 protein NRDE-2 PF08424.10 CCD24528.1 - 0.048 12.8 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Kinase-like PF14531.6 CCD24528.1 - 0.053 12.8 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pox_A_type_inc PF04508.12 CCD24528.1 - 0.074 12.9 0.3 0.53 10.2 0.5 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Glyco_hydro_16 PF00722.21 CCD24529.1 - 1.3e-46 158.3 0.9 1.3e-46 158.3 0.9 2.6 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 AA_permease PF00324.21 CCD24530.1 - 1.3e-138 462.6 33.8 1.7e-138 462.2 33.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD24530.1 - 2.2e-39 135.5 36.1 2.6e-39 135.3 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease CobD_Cbib PF03186.13 CCD24530.1 - 0.0036 16.5 0.0 0.018 14.3 0.0 2.1 1 1 1 2 2 2 1 CobD/Cbib protein DUF2269 PF10027.9 CCD24530.1 - 0.79 9.8 10.0 1 9.4 0.2 3.1 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2269) Gp_dh_C PF02800.20 CCD24531.1 - 3.9e-72 241.0 0.0 6.4e-72 240.3 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CCD24531.1 - 5.5e-38 129.4 0.0 1.3e-37 128.1 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CCD24531.1 - 0.1 12.7 0.4 0.39 10.8 0.4 2.2 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Biotin_lipoyl PF00364.22 CCD24532.1 - 1.8e-21 75.7 0.5 4.8e-21 74.4 0.5 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CCD24532.1 - 8.7e-06 26.0 0.0 2.1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CCD24532.1 - 0.0052 16.6 1.3 0.57 10.1 0.0 3.4 2 1 1 3 3 3 1 Biotin-lipoyl like SRP9-21 PF05486.12 CCD24532.1 - 0.47 10.9 2.8 0.7 10.3 0.1 2.4 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) FGGY_N PF00370.21 CCD24533.1 - 3.5e-21 75.9 0.0 8.4e-12 45.2 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CCD24533.1 - 5.2e-12 45.9 0.0 3.1e-11 43.4 0.0 2.2 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF3533 PF12051.8 CCD24535.1 - 1.9e-128 428.6 24.8 2.3e-128 428.4 24.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.12 CCD24535.1 - 0.26 11.2 0.1 0.26 11.2 0.1 3.0 2 1 0 2 2 2 0 CDR ABC transporter TPR_17 PF13431.6 CCD24536.1 - 0.00015 21.9 1.4 1.1 9.8 0.0 4.5 3 0 0 3 3 3 2 Tetratricopeptide repeat RPAP3_C PF13877.6 CCD24536.1 - 0.32 11.6 10.0 1.1 9.9 1.0 4.2 4 1 0 4 4 4 0 Potential Monad-binding region of RPAP3 TPR_8 PF13181.6 CCD24536.1 - 1.2 9.6 10.2 6.4 7.3 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3533 PF12051.8 CCD24537.1 - 8.7e-113 377.1 16.9 1.2e-112 376.7 16.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.12 CCD24537.1 - 0.014 15.3 0.0 0.014 15.3 0.0 4.0 4 0 0 4 4 4 0 CDR ABC transporter PMT PF02366.18 CCD24538.1 - 6.4e-89 297.7 20.1 6.4e-89 297.7 20.1 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCD24538.1 - 2.9e-56 190.2 16.9 2.9e-56 190.2 16.9 2.3 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCD24538.1 - 2.1e-23 83.1 0.2 5.6e-23 81.7 0.3 1.6 2 0 0 2 2 2 1 MIR domain AzlD PF05437.12 CCD24538.1 - 4.2 7.6 16.4 5.9 7.1 1.5 3.6 2 1 1 3 3 3 0 Branched-chain amino acid transport protein (AzlD) WD40 PF00400.32 CCD24539.1 - 7e-32 109.0 26.7 7.3e-07 29.8 0.1 11.0 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD24539.1 - 4.7e-10 39.6 4.3 1.1 9.6 0.0 7.3 5 3 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCD24539.1 - 0.0001 21.4 0.7 0.42 9.5 0.2 4.2 5 1 0 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CCD24539.1 - 0.0047 16.3 3.7 0.11 11.8 0.3 3.1 3 1 0 3 3 3 2 WD40-like domain PD40 PF07676.12 CCD24539.1 - 2.9 7.9 4.4 40 4.3 0.0 3.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat CENP-B_dimeris PF09026.10 CCD24539.1 - 7.2 7.1 6.9 0.36 11.2 0.3 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Rhodanese PF00581.20 CCD24540.1 - 2.2e-08 34.6 0.1 3e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Rhodanese-like domain YnfE PF17452.2 CCD24540.1 - 0.097 13.0 0.2 0.21 11.9 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized YnfE-like FTHFS PF01268.19 CCD24541.1 - 1.8e-251 835.2 0.2 2.8e-251 834.6 0.2 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CCD24541.1 - 8.2e-62 207.2 0.3 2.2e-61 205.9 0.3 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CCD24541.1 - 3.7e-38 130.4 0.6 8.3e-38 129.2 0.6 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.27 CCD24541.1 - 0.018 14.6 0.1 0.051 13.1 0.1 1.7 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Glyco_trans_1_4 PF13692.6 CCD24541.1 - 0.02 15.3 0.0 0.074 13.5 0.0 2.0 1 0 0 1 1 1 0 Glycosyl transferases group 1 AdoHcyase_NAD PF00670.21 CCD24541.1 - 0.04 14.0 3.3 0.66 10.0 0.2 3.1 3 1 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CbiA PF01656.23 CCD24541.1 - 0.099 12.7 0.0 0.47 10.5 0.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Torsin PF06309.11 CCD24542.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Torsin RNA_helicase PF00910.22 CCD24542.1 - 0.015 15.7 0.0 0.035 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 CCD24542.1 - 0.03 14.4 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CCD24542.1 - 0.046 14.3 0.2 0.1 13.1 0.1 1.8 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 CCD24542.1 - 0.059 13.7 0.0 0.096 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 CCD24542.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 CCD24542.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Mvb12 PF09452.10 CCD24543.1 - 6.4e-38 129.1 1.7 8.2e-38 128.7 1.7 1.1 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 ETF PF01012.21 CCD24544.1 - 1.8e-35 122.5 0.0 2.4e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Hydrolase PF00702.26 CCD24545.1 - 1.1e-16 61.8 0.0 2.3e-16 60.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CCD24545.1 - 8.5e-12 45.9 0.0 1.2e-11 45.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CCD24545.1 - 2.9e-10 40.3 0.9 1.7e-08 34.5 0.0 3.0 2 2 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CCD24545.1 - 1.2e-05 25.5 1.0 0.17 11.9 0.5 2.6 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase S6PP PF05116.13 CCD24545.1 - 0.073 12.6 0.1 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase CALCOCO1 PF07888.11 CCD24545.1 - 0.073 11.9 0.1 0.1 11.5 0.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like RE_BsaWI PF18643.1 CCD24545.1 - 0.08 12.9 0.5 0.77 9.7 0.4 2.4 1 1 0 1 1 1 0 BsaWI restriction endonuclease type 2 Peptidase_C34 PF05413.11 CCD24545.1 - 0.08 13.2 0.3 0.24 11.7 0.1 2.0 2 0 0 2 2 2 0 Putative closterovirus papain-like endopeptidase Thioredoxin PF00085.20 CCD24546.1 - 1e-31 109.0 0.5 1.1e-31 108.8 0.5 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 CCD24546.1 - 1.1e-08 34.9 0.2 1.3e-08 34.7 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CCD24546.1 - 1.9e-07 31.5 0.4 6.4e-06 26.6 0.4 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CCD24546.1 - 1.3e-06 28.7 0.1 4.6e-06 26.9 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CCD24546.1 - 6.5e-05 22.8 0.1 7.7e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 CCD24546.1 - 0.00045 19.7 0.1 0.00052 19.5 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DIM1 PF02966.16 CCD24546.1 - 0.0015 18.4 0.1 0.0016 18.2 0.1 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Redoxin PF08534.10 CCD24546.1 - 0.0018 18.0 0.1 0.0028 17.4 0.1 1.5 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 CCD24546.1 - 0.0052 16.9 0.3 0.012 15.8 0.3 1.6 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 CCD24546.1 - 0.0083 16.0 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein HyaE PF07449.11 CCD24546.1 - 0.018 15.0 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DSBA PF01323.20 CCD24546.1 - 0.1 12.4 0.4 0.27 11.0 0.2 1.7 1 1 1 2 2 2 0 DSBA-like thioredoxin domain MMR_HSR1_C PF08438.10 CCD24547.1 - 4.3e-36 123.9 0.1 6.8e-36 123.2 0.1 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 CCD24547.1 - 4.2e-20 71.9 0.0 9.3e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCD24547.1 - 1.1e-07 31.5 0.1 2.6e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CCD24547.1 - 0.00098 19.2 0.0 0.0059 16.7 0.0 2.3 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 CCD24547.1 - 0.00099 18.7 0.1 0.31 10.5 0.1 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 CCD24547.1 - 0.0052 16.2 0.1 2 7.7 0.0 2.2 2 0 0 2 2 2 2 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 CCD24547.1 - 0.0066 16.3 0.2 3.1 7.5 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CCD24547.1 - 0.019 14.9 1.3 2.9 7.8 0.0 2.6 3 0 0 3 3 3 0 RsgA GTPase Ploopntkinase3 PF18751.1 CCD24547.1 - 0.036 14.0 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 KTI12 PF08433.10 CCD24547.1 - 0.086 12.3 0.0 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 MeaB PF03308.16 CCD24547.1 - 0.091 11.7 0.2 0.85 8.5 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 CCD24547.1 - 0.13 12.1 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CCD24547.1 - 0.14 12.7 0.0 0.48 10.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter RSF PF14876.6 CCD24548.1 - 2.1e-13 50.0 5.2 2.1e-13 50.0 5.2 2.8 3 1 0 3 3 3 1 Respiratory growth transcriptional regulator zf-ZPR1 PF03367.13 CCD24549.1 - 7.4e-115 380.2 4.5 4.3e-57 192.4 0.8 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 CCD24549.1 - 0.0011 19.0 2.8 0.73 9.9 0.5 2.6 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2294 PF10057.9 CCD24549.1 - 0.11 12.7 0.2 0.45 10.7 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) Cytochrom_C_2 PF01322.20 CCD24549.1 - 0.16 12.9 2.0 2.2 9.2 0.5 2.8 3 0 0 3 3 3 0 Cytochrome C' zinc-ribbons_6 PF07191.12 CCD24549.1 - 0.21 11.6 6.1 0.31 11.0 1.0 2.7 2 1 0 2 2 2 0 zinc-ribbons zf-RRPl_C4 PF17026.5 CCD24549.1 - 0.72 10.0 6.7 1.8 8.7 0.4 2.9 2 1 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type OrfB_Zn_ribbon PF07282.11 CCD24549.1 - 6.9 6.7 7.1 18 5.3 0.0 3.3 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.6 CCD24549.1 - 8.9 6.2 14.7 6.1 6.7 0.6 4.3 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.7 CCD24549.1 - 9.2 6.4 12.8 4.3 7.4 2.3 3.6 2 2 1 3 3 3 0 Double zinc ribbon AATase PF07247.12 CCD24550.1 - 1e-67 228.8 5.0 1.3e-67 228.5 5.0 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 CCD24550.1 - 1.3e-05 24.0 0.3 0.0018 17.0 0.1 2.1 2 0 0 2 2 2 2 Condensation domain WES_acyltransf PF03007.16 CCD24550.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain eIF_4G1 PF12152.8 CCD24550.1 - 0.066 13.4 0.5 2.3 8.5 0.2 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 4G1 RTA1 PF04479.13 CCD24551.1 - 1.4e-62 211.0 12.9 1.4e-62 211.0 12.9 1.3 2 0 0 2 2 2 1 RTA1 like protein DUF4257 PF14074.6 CCD24551.1 - 1.2 9.4 5.4 1.9 8.8 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) Ribosomal_S2 PF00318.20 CCD24552.1 - 9.3e-25 87.1 0.4 1.3e-13 50.6 0.0 2.4 2 1 1 3 3 3 2 Ribosomal protein S2 40S_SA_C PF16122.5 CCD24552.1 - 0.033 15.5 11.1 0.07 14.5 11.1 1.6 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus MRP-S33 PF08293.11 CCD24553.1 - 3.8e-34 116.8 0.2 4.8e-34 116.5 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Gpi1 PF05024.15 CCD24554.1 - 7e-56 189.3 17.8 7e-56 189.3 17.8 1.8 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Ion_trans PF00520.31 CCD24555.1 - 3.9e-100 334.1 114.0 1.9e-35 122.3 17.7 5.1 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.32 CCD24555.1 - 0.01 15.4 0.0 0.046 13.3 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CCD24555.1 - 0.13 12.3 0.0 0.55 10.3 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain GPHH PF16905.5 CCD24555.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated CRM1_C PF08767.11 CCD24556.1 - 4.5e-134 446.7 2.5 4.5e-134 446.7 2.5 3.1 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 CCD24556.1 - 1.4e-36 125.8 6.4 1.4e-36 125.8 6.4 3.8 4 0 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 CCD24556.1 - 5.1e-32 109.3 2.2 1.3e-31 108.0 2.2 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CCD24556.1 - 3.5e-28 97.5 0.4 2.4e-27 94.8 0.4 2.7 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 CCD24556.1 - 5.2e-16 57.9 0.9 5.2e-16 57.9 0.9 2.1 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 CCD24556.1 - 1.2e-15 57.2 0.9 7e-15 54.7 0.2 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF507 PF04368.13 CCD24556.1 - 0.00036 20.5 0.7 0.38 10.7 0.2 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF507) V-ATPase_H_C PF11698.8 CCD24556.1 - 0.0072 16.4 2.6 0.11 12.7 0.2 3.4 3 0 0 3 3 3 1 V-ATPase subunit H DUF3385 PF11865.8 CCD24556.1 - 0.12 12.3 6.2 0.19 11.6 0.1 3.8 3 1 0 4 4 4 0 Domain of unknown function (DUF3385) DrrA_P4M PF14860.6 CCD24556.1 - 0.2 11.6 1.7 8.9 6.2 0.1 3.8 3 0 0 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain Ribosomal_L3 PF00297.22 CCD24557.1 - 4.4e-17 62.1 0.8 1.3e-13 50.7 0.6 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 PuR_N PF09182.10 CCD24558.1 - 1.6 8.7 5.1 5.8 6.9 0.1 3.2 3 0 0 3 3 3 0 Bacterial purine repressor, N-terminal Thiamine_BP PF01910.17 CCD24560.1 - 8.7e-16 57.6 0.1 1e-15 57.4 0.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Fijivirus_P9-2 PF06837.11 CCD24560.1 - 0.031 13.8 0.0 0.033 13.7 0.0 1.0 1 0 0 1 1 1 0 Fijivirus P9-2 protein ANAPC4_WD40 PF12894.7 CCD24561.1 - 0.00037 20.7 0.0 0.35 11.2 0.0 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCD24561.1 - 0.0034 18.2 0.1 6.7 7.8 0.0 3.7 2 1 1 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CCD24561.1 - 0.014 14.4 1.6 0.023 13.6 0.1 2.1 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GSHPx PF00255.19 CCD24562.1 - 2.5e-49 165.4 0.7 3.2e-49 165.0 0.7 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CCD24562.1 - 3.1e-05 23.9 0.1 0.00018 21.4 0.1 2.0 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CCD24562.1 - 0.012 15.3 0.1 0.065 13.0 0.1 2.0 1 1 0 1 1 1 0 Redoxin WD40 PF00400.32 CCD24563.1 - 4.4e-07 30.5 6.8 1.1 10.2 0.0 6.5 6 0 0 6 6 6 2 WD domain, G-beta repeat HPS3_N PF14761.6 CCD24563.1 - 0.015 14.8 1.0 19 4.7 0.1 3.5 3 1 0 3 3 3 0 Hermansky-Pudlak syndrome 3 Lgl_C PF08596.10 CCD24563.1 - 0.016 14.0 1.1 0.15 10.8 0.1 2.5 2 1 1 3 3 3 0 Lethal giant larvae(Lgl) like, C-terminal Ge1_WD40 PF16529.5 CCD24563.1 - 0.017 14.1 0.0 0.04 12.9 0.0 1.7 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 CCD24563.1 - 0.023 15.0 0.7 30 5.0 0.3 4.1 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 CCD24563.1 - 0.11 11.8 0.1 0.45 9.7 0.1 2.0 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DIE2_ALG10 PF04922.12 CCD24564.1 - 5e-110 368.5 38.0 5e-110 368.5 38.0 1.5 2 0 0 2 2 2 1 DIE2/ALG10 family SMI1_KNR4 PF09346.10 CCD24565.1 - 5.1e-29 101.3 0.0 5.1e-29 101.3 0.0 3.1 3 1 1 4 4 4 1 SMI1 / KNR4 family (SUKH-1) Spo12 PF05032.12 CCD24566.1 - 1.4e-17 63.2 4.8 1.4e-17 63.2 4.8 2.4 2 0 0 2 2 2 1 Spo12 family Band_7 PF01145.25 CCD24567.1 - 7.7e-22 78.1 0.9 1.2e-21 77.6 0.9 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 CCD24567.1 - 0.085 13.0 0.3 0.19 11.9 0.3 1.6 1 0 0 1 1 1 0 Mediator complex subunit 2 Ank_2 PF12796.7 CCD24568.1 - 6.9e-36 122.7 0.1 1.5e-12 48.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CCD24568.1 - 5.2e-33 112.7 0.0 1.1e-11 44.7 0.0 5.9 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCD24568.1 - 3.6e-32 110.3 0.5 1.2e-10 41.7 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCD24568.1 - 4.9e-31 103.3 0.1 0.00052 20.3 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 CCD24568.1 - 1.6e-27 94.7 0.2 3.2e-06 27.3 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 CCD24569.1 - 3.7e-27 94.7 5.7 1.5e-11 44.7 0.1 3.7 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) SPX PF03105.19 CCD24569.1 - 3.9e-23 83.0 26.7 5.8e-10 39.6 1.1 4.6 2 1 2 4 4 4 3 SPX domain Ank_4 PF13637.6 CCD24569.1 - 5.9e-23 80.9 7.0 9.9e-07 29.2 0.0 5.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCD24569.1 - 1.2e-16 59.1 8.7 0.059 13.9 0.1 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 CCD24569.1 - 2.7e-16 59.2 14.7 0.0045 17.4 0.0 6.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CCD24569.1 - 3.6e-16 59.0 8.7 0.011 16.0 0.3 5.7 5 0 0 5 5 5 4 Ankyrin repeats (many copies) RTT107_BRCT_6 PF16771.5 CCD24570.1 - 2.2e-23 82.6 10.4 6.3e-20 71.4 2.4 4.5 3 1 1 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain RTT107_BRCT_5 PF16770.5 CCD24570.1 - 4.4e-18 65.0 0.0 3e-17 62.3 0.0 2.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 CCD24570.1 - 7.1e-12 45.5 11.3 0.00021 21.6 0.1 4.7 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CCD24570.1 - 4.6e-07 29.7 0.0 0.00035 20.4 0.0 2.9 2 0 0 2 2 2 2 twin BRCT domain Globin PF00042.22 CCD24571.1 - 2.3e-09 37.8 0.0 9.1e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.24 CCD24571.1 - 1.4e-08 35.0 0.0 2.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CCD24571.1 - 1.7e-07 31.8 0.0 5.6e-07 30.2 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CCD24571.1 - 0.068 13.3 0.1 0.26 11.4 0.1 1.9 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Protoglobin PF11563.8 CCD24571.1 - 0.095 12.6 0.1 0.3 11.0 0.1 1.8 1 1 0 1 1 1 0 Protoglobin ApoO PF09769.9 CCD24572.1 - 2.8e-29 101.7 0.0 3.9e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Apolipoprotein O Taeniidae_ag PF05596.11 CCD24573.1 - 0.069 13.1 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Taeniidae antigen Kelch_5 PF13854.6 CCD24574.1 - 5e-34 115.7 7.8 1.3e-06 28.2 0.7 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 CCD24574.1 - 2.7e-31 107.3 13.5 5.3e-05 23.1 0.3 7.1 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.6 CCD24574.1 - 2.5e-29 100.9 2.5 6.1e-05 23.2 0.0 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 CCD24574.1 - 6.1e-28 96.2 9.0 7.5e-05 22.9 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 CCD24574.1 - 2e-21 75.3 4.5 9e-07 28.4 0.1 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 CCD24574.1 - 1.9e-15 56.1 7.8 0.014 15.3 0.1 6.8 6 0 0 6 6 6 5 Kelch motif Neur_chan_memb PF02932.16 CCD24575.1 - 0.51 10.3 4.7 0.88 9.6 4.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.16 CCD24575.1 - 3.3 6.5 5.1 3.9 6.3 5.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PFK PF00365.20 CCD24576.1 - 8.4e-183 606.1 3.1 6.2e-105 350.6 0.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase Pfk_N PF18468.1 CCD24576.1 - 1.3e-27 96.1 0.3 2.6e-27 95.1 0.3 1.6 1 0 0 1 1 1 1 Phosphofructokinase N-terminal domain yeast DAGK_cat PF00781.24 CCD24576.1 - 0.023 14.3 0.1 0.082 12.5 0.1 2.0 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain UVR PF02151.19 CCD24576.1 - 0.45 10.3 1.8 1.1 9.1 0.4 2.2 2 0 0 2 2 2 0 UvrB/uvrC motif TT_ORF1 PF02956.14 CCD24577.1 - 0.066 11.9 26.1 0.058 12.1 26.1 1.2 1 0 0 1 1 1 0 TT viral orf 1 CDC45 PF02724.14 CCD24577.1 - 1.3 7.3 11.0 1.1 7.4 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Rrn6 PF10214.9 CCD24577.1 - 1.9 6.9 10.5 1.8 7.0 10.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor EOS1 PF12326.8 CCD24577.1 - 4.1 7.3 6.2 4.3 7.2 6.2 1.2 1 0 0 1 1 1 0 N-glycosylation protein DUF1708 PF08101.11 CCD24578.1 - 3.5e-142 474.6 14.4 3.5e-142 474.6 14.4 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF1708) RhoGAP PF00620.27 CCD24578.1 - 0.0076 16.1 0.3 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain GTP_EFTU PF00009.27 CCD24579.1 - 4.8e-60 202.4 0.3 6.6e-60 202.0 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CCD24579.1 - 7.3e-28 97.1 0.1 1.4e-27 96.2 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CCD24579.1 - 2.8e-20 72.5 2.6 4.1e-20 72.0 1.6 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCD24579.1 - 0.00011 22.2 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCD24579.1 - 0.0076 16.2 0.1 0.039 13.8 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 CCD24579.1 - 0.025 14.3 0.3 7.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 CCD24579.1 - 0.039 13.5 0.8 0.073 12.7 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_sub_h PF10775.9 CCD24580.1 - 3.1e-20 71.9 0.1 5.1e-20 71.2 0.1 1.4 1 0 0 1 1 1 1 ATP synthase complex subunit h DUF2407 PF10302.9 CCD24580.1 - 0.031 14.8 0.0 0.041 14.5 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ras PF00071.22 CCD24581.1 - 4e-50 169.6 0.0 4.9e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD24581.1 - 1.7e-30 105.7 0.1 4.5e-30 104.3 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD24581.1 - 3.3e-11 43.0 0.0 4.4e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 CCD24581.1 - 0.00073 19.9 0.2 0.0082 16.5 0.2 2.2 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 CCD24581.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCD24581.1 - 0.005 16.4 0.2 0.021 14.4 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CCD24581.1 - 0.0056 16.1 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CCD24581.1 - 0.0079 15.4 1.1 1.2 8.2 0.1 2.7 2 1 1 3 3 3 1 G-protein alpha subunit Pox_A32 PF04665.12 CCD24581.1 - 0.018 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 CCD24581.1 - 0.025 14.5 0.1 8.1 6.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 CCD24581.1 - 0.03 13.9 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 CCD24581.1 - 0.033 13.6 0.0 0.056 12.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 CCD24581.1 - 0.064 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CCD24581.1 - 0.075 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 CCD24581.1 - 0.09 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 CCD24581.1 - 0.11 12.6 0.6 0.23 11.6 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CCD24581.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain IF-2B PF01008.17 CCD24582.1 - 6.9e-89 297.8 1.2 5.3e-88 294.9 1.2 1.9 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF2621 PF11084.8 CCD24582.1 - 0.046 13.7 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) DUF4570 PF15134.6 CCD24582.1 - 0.08 13.0 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Lyase_1 PF00206.20 CCD24582.1 - 0.11 11.8 0.7 0.17 11.3 0.7 1.2 1 0 0 1 1 1 0 Lyase Aminotran_5 PF00266.19 CCD24583.1 - 5.1e-40 137.6 0.0 7.3e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Ribosomal_S30 PF04758.14 CCD24584.1 - 8.3e-30 102.8 5.6 9.1e-30 102.6 5.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 WH1 PF00568.23 CCD24585.1 - 1.6e-35 121.4 0.0 2.3e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 CCD24585.1 - 2.1e-06 27.4 1.0 4.7e-06 26.3 1.0 1.6 1 0 0 1 1 1 1 WH2 motif ECH_1 PF00378.20 CCD24586.1 - 1e-18 67.6 0.0 8.3e-18 64.6 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CCD24586.1 - 3.4e-08 33.4 0.0 6.4e-08 32.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Init_tRNA_PT PF04179.12 CCD24586.1 - 0.087 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Fungal_trans PF04082.18 CCD24587.1 - 2.4e-19 69.4 2.3 4.8e-19 68.4 2.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD24587.1 - 8.7e-06 25.8 10.8 2.2e-05 24.5 10.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBM_21 PF03370.13 CCD24588.1 - 3.5e-25 88.4 7.8 3.5e-25 88.4 7.8 3.0 3 0 0 3 3 3 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CCD24588.1 - 0.0091 16.6 7.3 0.0091 16.6 7.3 3.5 2 1 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) NOP19 PF10863.8 CCD24588.1 - 0.057 13.2 2.6 0.22 11.4 2.6 2.0 1 0 0 1 1 1 0 Nucleolar protein 19 Pkinase PF00069.25 CCD24589.1 - 1e-70 238.1 0.4 3.5e-64 216.7 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24589.1 - 9.1e-35 120.2 0.1 6.6e-33 114.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CCD24589.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCD24589.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Utp11 PF03998.13 CCD24590.1 - 1.2e-67 228.5 28.9 1.3e-67 228.3 28.9 1.0 1 0 0 1 1 1 1 Utp11 protein DUF2529 PF10740.9 CCD24590.1 - 0.0019 17.8 0.0 0.0059 16.3 0.0 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF2529) BRO1 PF03097.18 CCD24591.1 - 0.0032 16.3 0.6 0.0032 16.3 0.6 1.8 2 0 0 2 2 2 1 BRO1-like domain Aha1_N PF09229.11 CCD24592.1 - 0.042 14.0 0.5 0.054 13.7 0.5 1.1 1 0 0 1 1 1 0 Activator of Hsp90 ATPase, N-terminal TFIIS_M PF07500.14 CCD24593.1 - 7.3e-26 90.9 2.4 7.3e-26 90.9 2.4 2.4 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CCD24593.1 - 1.6e-17 63.0 6.4 3.2e-17 62.1 6.4 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CCD24593.1 - 1.8e-08 34.3 2.3 1.8e-08 34.3 2.3 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain HypA PF01155.19 CCD24593.1 - 0.047 13.7 4.9 0.13 12.3 0.7 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PIN_4 PF13638.6 CCD24593.1 - 0.22 11.8 7.9 1.3 9.3 4.9 2.8 2 1 0 2 2 2 0 PIN domain RRM_1 PF00076.22 CCD24594.1 - 2.4e-20 72.1 0.0 5.7e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 CCD24594.1 - 1e-07 32.3 0.4 1e-07 32.3 0.4 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 CCD24594.1 - 4.9e-07 29.2 0.2 9.8e-07 28.3 0.2 1.5 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_occluded PF16842.5 CCD24594.1 - 0.0003 20.6 0.0 0.00077 19.3 0.0 1.7 2 0 0 2 2 2 1 Occluded RNA-recognition motif ASF1_hist_chap PF04729.13 CCD24594.1 - 0.0088 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 ASF1 like histone chaperone RRM_7 PF16367.5 CCD24594.1 - 0.096 12.8 0.0 0.3 11.2 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif zf-rbx1 PF12678.7 CCD24595.1 - 8.1e-06 26.0 9.3 8.4e-06 26.0 7.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CCD24595.1 - 2.1e-05 24.8 10.9 2.4e-05 24.6 4.5 2.9 2 1 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 CCD24595.1 - 0.0031 17.7 6.4 0.0061 16.7 5.9 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_11 PF17123.5 CCD24595.1 - 0.0097 15.6 10.8 0.01 15.6 2.1 3.1 2 0 0 2 2 2 1 RING-like zinc finger DUF2157 PF09925.9 CCD24595.1 - 0.012 15.4 0.1 0.015 15.1 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) zf-C3HC4 PF00097.25 CCD24595.1 - 0.021 14.7 8.2 0.16 11.9 8.2 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCD24595.1 - 0.03 14.2 0.7 0.03 14.2 0.7 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CCD24595.1 - 0.037 13.7 0.3 0.037 13.7 0.3 2.9 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 CCD24595.1 - 0.061 13.4 7.1 0.049 13.7 4.9 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 CCD24595.1 - 3.7 7.7 9.9 8.4 6.5 7.3 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RNase_PH PF01138.21 CCD24596.1 - 1.8e-16 60.8 0.1 2.5e-16 60.4 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Arrestin_N PF00339.29 CCD24597.1 - 1.3e-18 67.4 0.0 1.3e-18 67.4 0.0 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CCD24597.1 - 1.3e-06 28.9 0.3 1.3e-06 28.9 0.3 3.5 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Lipocalin_7 PF14651.6 CCD24597.1 - 0.027 14.4 0.9 0.065 13.2 0.9 1.7 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family RRM_1 PF00076.22 CCD24598.1 - 1.1e-44 150.1 0.0 2.7e-21 75.2 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD24598.1 - 0.00013 22.0 0.1 0.34 11.0 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CCD24598.1 - 0.0031 17.5 0.1 0.96 9.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 CCD24598.1 - 0.017 15.1 0.0 0.72 9.9 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_5 PF13893.6 CCD24598.1 - 0.041 13.5 0.0 2 8.0 0.0 2.3 1 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCD24598.1 - 0.085 12.7 0.0 3.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif AAA PF00004.29 CCD24599.1 - 8.7e-43 145.9 0.0 1.6e-42 145.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCD24599.1 - 3.1e-14 52.5 0.4 9e-14 51.0 0.0 2.0 3 0 0 3 3 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CCD24599.1 - 1.2e-07 31.6 0.9 2.8e-07 30.4 0.9 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CCD24599.1 - 1.3e-06 28.7 0.0 2.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CCD24599.1 - 1.4e-06 28.4 0.0 7.7e-06 25.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCD24599.1 - 2.1e-05 25.0 0.1 0.00032 21.1 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CCD24599.1 - 3.3e-05 24.2 0.2 0.0094 16.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CCD24599.1 - 9.3e-05 22.2 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CCD24599.1 - 0.0013 19.3 0.4 0.023 15.2 0.0 2.7 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CCD24599.1 - 0.0015 18.3 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 CCD24599.1 - 0.0022 18.2 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CCD24599.1 - 0.0042 17.3 0.0 0.0085 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CCD24599.1 - 0.007 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CCD24599.1 - 0.011 15.1 0.2 0.028 13.8 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CCD24599.1 - 0.011 14.9 0.0 0.028 13.6 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain DUF2072 PF09845.9 CCD24599.1 - 0.019 15.3 0.2 0.038 14.3 0.2 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein TsaE PF02367.17 CCD24599.1 - 0.02 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CCD24599.1 - 0.022 14.8 0.0 0.049 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CCD24599.1 - 0.023 14.2 0.0 0.077 12.4 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.26 CCD24599.1 - 0.029 14.1 0.0 0.17 11.6 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.22 CCD24599.1 - 0.041 14.3 0.0 0.095 13.1 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 CCD24599.1 - 0.048 14.0 0.1 0.65 10.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CCD24599.1 - 0.052 13.3 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CCD24599.1 - 0.054 13.1 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 CCD24599.1 - 0.069 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 CCD24599.1 - 0.082 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CCD24599.1 - 0.091 12.0 0.0 0.25 10.6 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 CCD24599.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 CCD24599.1 - 0.13 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CCD24599.1 - 0.15 12.0 0.0 0.43 10.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain ATG16 PF08614.11 CCD24599.1 - 0.23 11.7 3.1 0.4 10.9 3.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) MIF4G PF02854.19 CCD24600.1 - 2.1e-49 168.1 1.3 3.3e-49 167.4 1.3 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 CCD24600.1 - 4.7e-22 78.0 1.5 4.7e-22 78.0 1.5 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 SseC PF04888.12 CCD24600.1 - 0.21 11.2 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family TYW3 PF02676.14 CCD24601.1 - 2.4e-66 223.2 0.3 4.5e-66 222.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase TYW3 DUF2347 PF09804.9 CCD24601.1 - 0.047 13.3 0.5 0.066 12.8 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) MAT1 PF06391.13 CCD24601.1 - 0.099 12.5 13.6 0.16 11.8 13.6 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Cys_Met_Meta_PP PF01053.20 CCD24602.1 - 1.8e-144 481.0 0.0 2e-144 480.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CCD24602.1 - 1.8e-10 40.5 0.0 2.7e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CCD24602.1 - 9.1e-10 38.0 0.3 1.3e-09 37.5 0.3 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CCD24602.1 - 1.4e-08 34.5 0.0 2.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CCD24602.1 - 3.5e-06 26.5 0.0 5.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 CCD24602.1 - 0.00041 19.0 0.1 0.00083 18.0 0.1 1.5 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 CCD24602.1 - 0.035 13.0 0.0 0.049 12.5 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Asparaginase_C PF17763.1 CCD24602.1 - 0.088 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain SelA PF03841.13 CCD24602.1 - 0.15 11.0 0.4 0.89 8.5 0.4 1.9 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase CPSase_L_D2 PF02786.17 CCD24602.1 - 0.18 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Aconitase PF00330.20 CCD24603.1 - 3.6e-150 501.0 0.0 4.6e-150 500.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCD24603.1 - 1.9e-47 160.9 0.0 3.8e-47 159.9 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain PI3_PI4_kinase PF00454.27 CCD24604.1 - 4e-43 148.0 0.0 9.7e-41 140.2 0.0 2.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CCD24604.1 - 8.5e-28 97.0 0.1 2.6e-27 95.4 0.1 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CCM2_C PF16545.5 CCD24604.1 - 0.089 13.3 0.8 29 5.3 0.0 3.5 3 0 0 3 3 3 0 Cerebral cavernous malformation protein, harmonin-homology DUF5354 PF17305.2 CCD24604.1 - 0.25 11.6 1.2 5.7 7.2 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5354) UQ_con PF00179.26 CCD24605.1 - 1.3e-34 118.9 0.0 1.7e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Polysacc_deac_1 PF01522.21 CCD24606.1 - 6.9e-26 90.6 0.0 1.2e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase RuBisCO_small PF00101.20 CCD24606.1 - 0.055 13.5 0.0 9 6.4 0.0 2.3 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain GRIP PF01465.20 CCD24607.1 - 2.6e-13 49.6 0.4 7.1e-13 48.2 0.4 1.8 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.11 CCD24607.1 - 0.00017 20.6 152.7 0.00092 18.2 19.2 6.7 1 1 5 7 7 7 5 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 CCD24607.1 - 0.0032 17.5 151.2 0.015 15.3 10.8 9.4 2 1 7 10 10 10 8 TPR/MLP1/MLP2-like protein OmpH PF03938.14 CCD24607.1 - 0.0058 17.0 3.7 0.0058 17.0 3.7 9.6 2 1 6 8 8 8 3 Outer membrane protein (OmpH-like) DUF2291 PF10054.9 CCD24607.1 - 1.1 8.9 10.1 0.61 9.8 5.7 2.8 2 1 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2291) DASH_Dad1 PF08649.10 CCD24607.1 - 1.5 9.0 7.3 2 8.7 1.0 4.5 2 0 0 2 2 2 0 DASH complex subunit Dad1 RasGEF PF00617.19 CCD24608.1 - 1.2e-56 191.7 0.2 1.2e-56 191.7 0.2 3.3 5 0 0 5 5 5 1 RasGEF domain RasGEF_N PF00618.20 CCD24608.1 - 1.3e-18 67.2 2.1 8e-18 64.6 0.0 3.7 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_9 PF14604.6 CCD24608.1 - 5.8e-08 32.5 0.0 1.4e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CCD24608.1 - 1.6e-06 27.6 0.1 5.8e-06 25.8 0.1 2.1 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CCD24608.1 - 0.00026 20.6 0.0 0.00066 19.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF1631 PF07793.11 CCD24608.1 - 0.031 12.7 3.5 0.059 11.8 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) tRNA-synt_2 PF00152.20 CCD24609.1 - 1.4e-76 257.6 0.2 1.4e-76 257.6 0.2 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCD24609.1 - 3.3e-07 30.2 0.3 7.4e-07 29.1 0.3 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CCD24609.1 - 0.017 14.6 0.5 2.9 7.3 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) MAS20 PF02064.15 CCD24609.1 - 1 9.5 8.4 2.1 8.5 8.4 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor Atg14 PF10186.9 CCD24609.1 - 8.3 5.4 9.8 12 4.8 9.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 COX6B PF02297.17 CCD24610.1 - 0.049 13.9 0.3 0.077 13.2 0.3 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Arteri_env PF01606.16 CCD24610.1 - 0.05 13.5 0.0 0.06 13.2 0.0 1.0 1 0 0 1 1 1 0 Arterivirus envelope protein CHCH PF06747.13 CCD24610.1 - 0.11 12.6 3.0 0.81 9.9 2.9 2.1 1 1 1 2 2 2 0 CHCH domain Pet191_N PF10203.9 CCD24610.1 - 0.17 12.2 2.6 0.43 10.9 2.6 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 CCD24610.1 - 0.53 10.7 3.4 5 7.5 0.7 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Pkinase PF00069.25 CCD24611.1 - 7.2e-37 127.2 6.7 1.3e-34 119.8 0.1 4.2 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24611.1 - 2.6e-11 43.3 0.8 1.3e-10 41.1 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CCD24611.1 - 0.0078 15.6 0.1 0.021 14.2 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EMC3_TMCO1 PF01956.16 CCD24611.1 - 0.078 12.7 3.8 62 3.3 9.1 2.8 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF3420 PF11900.8 CCD24611.1 - 0.082 13.1 0.3 0.26 11.5 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) Rpp20 PF12328.8 CCD24611.1 - 0.11 12.4 9.0 0.4 10.7 9.0 1.9 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Roughex PF06020.11 CCD24611.1 - 0.19 10.8 6.3 0.39 9.8 6.3 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Mem_trans PF03547.18 CCD24611.1 - 0.29 9.5 1.8 0.21 9.9 0.1 1.7 2 0 0 2 2 2 0 Membrane transport protein Androgen_recep PF02166.16 CCD24611.1 - 2.2 7.1 12.1 3.6 6.3 12.1 1.2 1 0 0 1 1 1 0 Androgen receptor GIT_SHD PF08518.11 CCD24612.1 - 5.8e-25 86.6 5.2 8.1e-12 44.5 0.4 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT TPR_12 PF13424.6 CCD24613.1 - 0.00083 19.6 0.1 0.059 13.7 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat SDA1 PF05285.12 CCD24613.1 - 0.0017 17.9 18.0 0.0017 17.9 18.0 1.6 2 0 0 2 2 2 1 SDA1 SHNi-TPR PF10516.9 CCD24613.1 - 0.0032 16.9 0.0 0.077 12.5 0.0 2.8 3 0 0 3 3 3 1 SHNi-TPR TPR_1 PF00515.28 CCD24613.1 - 0.078 12.8 4.3 1.6 8.7 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat AP-5_subunit_s1 PF15001.6 CCD24613.1 - 0.36 10.8 3.0 0.6 10.1 3.0 1.3 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 TPR_8 PF13181.6 CCD24613.1 - 0.61 10.5 5.2 12 6.4 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Ycf1 PF05758.12 CCD24613.1 - 1.2 6.9 9.7 1.8 6.3 9.7 1.2 1 0 0 1 1 1 0 Ycf1 DUF5523 PF17661.1 CCD24613.1 - 3.7 7.2 18.9 0.44 10.2 14.8 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5523) UPF0121 PF03661.13 CCD24614.1 - 1.8e-26 93.0 15.2 2.2e-26 92.7 15.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) rve PF00665.26 CCD24615.1 - 0.00023 21.3 0.0 0.00058 20.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain CH PF00307.31 CCD24615.1 - 3.8 7.7 7.2 0.95 9.7 3.2 2.1 2 0 0 2 2 2 0 Calponin homology (CH) domain Ribosomal_S3Ae PF01015.18 CCD24617.1 - 3.6e-87 291.2 5.3 4.3e-87 290.9 5.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 CCD24617.1 - 0.034 13.7 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region HIGH_NTase1_ass PF16581.5 CCD24617.1 - 0.045 13.8 0.2 0.061 13.3 0.2 1.2 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Ras PF00071.22 CCD24618.1 - 4.2e-28 98.0 0.0 5e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD24618.1 - 4.4e-20 72.1 0.0 6.1e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DLIC PF05783.11 CCD24618.1 - 0.00099 18.1 0.2 0.039 12.8 0.1 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Gtr1_RagA PF04670.12 CCD24618.1 - 0.0015 17.9 0.1 0.0017 17.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CCD24618.1 - 0.0024 17.3 0.1 0.003 17.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCD24618.1 - 0.01 15.9 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 CCD24618.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region STAT2_C PF12188.8 CCD24618.1 - 0.18 11.8 0.1 0.65 10.0 0.0 2.0 2 0 0 2 2 2 0 Signal transducer and activator of transcription 2 C terminal AAA_lid_10 PF17872.1 CCD24619.1 - 4.7e-41 138.9 0.0 1.5e-40 137.3 0.0 1.9 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 CCD24619.1 - 2.6e-19 69.9 0.0 5.8e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.18 CCD24619.1 - 5.3e-11 42.4 0.1 1.3e-10 41.2 0.1 1.7 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.6 CCD24619.1 - 4.7e-06 26.9 0.0 2.4e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCD24619.1 - 0.00046 20.6 0.0 0.0078 16.6 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 CCD24619.1 - 0.00067 19.6 0.3 0.00067 19.6 0.3 2.5 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CCD24619.1 - 0.008 16.5 0.0 0.024 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CCD24619.1 - 0.033 14.6 0.0 0.47 10.9 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_11 PF13086.6 CCD24619.1 - 0.065 13.0 0.6 0.53 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CCD24619.1 - 0.13 12.0 0.1 0.63 9.7 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 CCD24619.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RVT_2 PF07727.14 CCD24620.1 - 3.7e-32 111.9 0.9 6.4e-32 111.1 0.9 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CCD24620.1 - 8.9e-14 51.7 0.0 2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CCD24620.1 - 3.1e-05 23.8 0.1 9.8e-05 22.1 0.1 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-C2H2_10 PF16588.5 CCD24620.1 - 5.8e-05 22.7 2.4 5.8e-05 22.7 2.4 2.2 2 0 0 2 2 2 1 C2H2 zinc-finger Methyltransf_FA PF12248.8 CCD24621.1 - 0.085 13.2 0.0 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 Farnesoic acid 0-methyl transferase SUR7 PF06687.12 CCD24621.1 - 0.19 11.3 11.8 0.97 9.0 11.8 2.1 1 1 0 1 1 1 0 SUR7/PalI family COPIIcoated_ERV PF07970.12 CCD24622.1 - 8.9e-30 104.2 0.1 1.3e-29 103.6 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CCD24622.1 - 1.8e-23 82.7 0.0 4e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) IBR PF01485.21 CCD24623.1 - 2.2e-15 56.6 26.3 3.5e-09 36.7 13.7 4.0 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 CCD24623.1 - 0.0044 17.3 8.6 0.0044 17.3 8.6 4.6 3 2 2 5 5 5 2 Ring finger domain zinc_ribbon_4 PF13717.6 CCD24623.1 - 2.7 8.0 26.8 4.3 7.4 0.0 5.7 5 0 0 5 5 5 0 zinc-ribbon domain SSrecog PF03531.14 CCD24624.1 - 5.8e-30 103.0 3.7 3.8e-28 97.2 0.1 3.7 4 0 0 4 4 4 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 CCD24624.1 - 1.7e-29 102.1 0.3 1.1e-26 93.1 0.1 2.7 2 0 0 2 2 2 2 POB3-like N-terminal PH domain Rtt106 PF08512.12 CCD24624.1 - 2.8e-28 98.2 0.1 1.2e-25 89.7 0.0 3.2 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Dak1 PF02733.17 CCD24625.1 - 3.4e-109 364.5 1.4 4.8e-109 364.0 1.4 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 CCD24625.1 - 3.7e-45 154.0 2.0 6.5e-45 153.1 2.0 1.4 1 0 0 1 1 1 1 DAK2 domain Dor1 PF04124.12 CCD24626.1 - 1.3e-46 158.9 8.1 2.2e-46 158.1 8.1 1.3 1 0 0 1 1 1 1 Dor1-like family ING PF12998.7 CCD24626.1 - 0.016 15.8 1.1 0.016 15.8 1.1 3.2 3 1 1 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding Lipoxygenase PF00305.19 CCD24626.1 - 0.018 13.5 0.2 0.029 12.8 0.2 1.2 1 0 0 1 1 1 0 Lipoxygenase Clathrin PF00637.20 CCD24626.1 - 0.02 14.8 2.0 0.14 12.0 0.7 3.0 2 1 0 2 2 2 0 Region in Clathrin and VPS TPR_7 PF13176.6 CCD24626.1 - 0.026 14.5 0.0 0.18 11.9 0.0 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat ABC_tran_CTD PF16326.5 CCD24626.1 - 0.051 13.8 1.4 0.18 12.1 0.1 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain Lzipper-MIP1 PF14389.6 CCD24626.1 - 0.055 13.8 0.1 0.23 11.8 0.1 2.0 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 TypeIII_RM_meth PF12564.8 CCD24626.1 - 0.063 13.4 0.3 0.17 12.0 0.3 1.8 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit FlgN PF05130.12 CCD24626.1 - 1.9 9.0 9.5 7.6 7.0 4.3 2.8 2 1 1 3 3 3 0 FlgN protein ESM4 PF15952.5 CCD24626.1 - 4.6 7.6 8.4 18 5.7 0.0 2.3 2 0 0 2 2 2 0 Enhancer of split M4 family C2 PF00168.30 CCD24627.1 - 1e-64 215.3 1.0 7.7e-22 77.5 0.0 5.7 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 CCD24627.1 - 0.0025 17.3 0.0 0.26 10.7 0.0 2.5 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain DOCK-C2 PF14429.6 CCD24627.1 - 0.0099 15.7 1.2 0.63 9.8 0.0 3.5 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins Ribosomal_L6e PF01159.19 CCD24628.1 - 4.8e-38 130.1 1.7 7e-38 129.6 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e Piwi PF02171.17 CCD24629.1 - 1e-62 212.1 0.0 1.5e-62 211.6 0.0 1.3 1 0 0 1 1 1 1 Piwi domain AGO_N PF18236.1 CCD24629.1 - 1.6e-51 173.7 0.4 1.6e-51 173.7 0.4 2.5 2 0 0 2 2 2 1 Argonaute N domain Ago_N_1 PF18351.1 CCD24629.1 - 4.6e-42 142.4 1.5 2.3e-41 140.1 1.5 2.4 1 0 0 1 1 1 1 Fungal Argonaute N-terminal domain ArgoN PF16486.5 CCD24629.1 - 0.0048 17.5 0.1 0.019 15.6 0.1 2.1 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 CCD24629.1 - 0.013 15.3 1.7 0.032 14.0 1.7 1.6 1 0 0 1 1 1 0 PAZ domain UPF0524 PF15823.5 CCD24629.1 - 0.16 11.4 0.1 0.16 11.4 0.1 2.1 2 0 0 2 2 2 0 UPF0524 of C3orf70 FKBP_C PF00254.28 CCD24630.1 - 7.4e-29 99.9 0.2 2.3e-28 98.4 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 CCD24630.1 - 1.5e-22 80.1 2.6 1.5e-22 80.1 2.6 2.6 2 2 0 2 2 2 1 Nucleoplasmin-like domain Peptidase_S49_N PF08496.10 CCD24630.1 - 0.67 10.0 21.4 0.89 9.6 1.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DcuC PF03606.15 CCD24630.1 - 1.2 7.5 0.0 1.2 7.5 0.0 2.0 3 0 0 3 3 3 0 C4-dicarboxylate anaerobic carrier CCSAP PF15748.5 CCD24630.1 - 2.1 8.4 23.5 2.9 8.0 11.8 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF4228 PF14009.6 CCD24630.1 - 3.9 7.8 9.0 15 6.0 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) AATF-Che1 PF13339.6 CCD24630.1 - 4.8 7.9 21.4 1.1 9.9 2.0 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor HMG-CoA_red PF00368.18 CCD24631.1 - 2.5e-143 477.5 0.1 3.6e-143 477.0 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 CCD24631.1 - 2e-46 157.7 1.0 4.6e-46 156.5 1.0 1.7 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 CCD24631.1 - 0.0054 16.6 8.9 0.0054 16.6 8.9 2.2 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Zn_clus PF00172.18 CCD24632.1 - 0.00088 19.3 8.9 0.0017 18.4 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sybindin PF04099.12 CCD24633.1 - 6.9e-19 68.2 0.4 8.2e-19 67.9 0.4 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CCD24633.1 - 0.00035 20.7 0.1 0.00046 20.3 0.1 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region LptD PF04453.14 CCD24633.1 - 0.0032 16.8 1.0 0.0042 16.4 1.0 1.2 1 0 0 1 1 1 1 LPS transport system D ENTH PF01417.20 CCD24634.1 - 9.1e-45 151.7 0.1 9.1e-45 151.7 0.1 1.8 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.16 CCD24634.1 - 3.1e-05 23.1 0.0 4.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 CCD24634.1 - 0.0051 16.7 0.0 0.0088 15.9 0.0 1.3 1 0 0 1 1 1 1 VHS domain Pro_isomerase PF00160.21 CCD24635.1 - 6.7e-50 169.4 0.2 7.7e-50 169.2 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cupin_5 PF06172.11 CCD24636.1 - 1e-43 148.9 0.0 1.2e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Dus PF01207.17 CCD24637.1 - 2.7e-79 266.5 0.0 3.5e-79 266.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-C2H2 PF00096.26 CCD24638.1 - 1.8e-06 28.0 15.2 0.0001 22.6 3.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCD24638.1 - 5.8e-06 26.5 11.5 4.1e-05 23.8 4.9 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCD24638.1 - 0.021 15.7 14.6 0.11 13.4 2.8 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger DnaJ PF00226.31 CCD24638.1 - 0.13 12.4 0.6 1.1 9.5 0.1 2.6 2 0 0 2 2 2 0 DnaJ domain zf-C2H2_jaz PF12171.8 CCD24638.1 - 0.29 11.5 1.4 1.2 9.5 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding ATP-synt_J PF04911.12 CCD24639.1 - 2.5e-28 97.4 0.3 2.8e-28 97.2 0.3 1.0 1 0 0 1 1 1 1 ATP synthase j chain Cys_Met_Meta_PP PF01053.20 CCD24640.1 - 1.7e-21 76.2 0.0 1.5e-11 43.4 0.1 2.8 3 0 0 3 3 3 2 Cys/Met metabolism PLP-dependent enzyme TPP_enzyme_M PF00205.22 CCD24641.1 - 3.9e-27 94.6 0.0 2.4e-26 92.1 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 CCD24641.1 - 1.4e-19 70.4 0.1 2.4e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CCD24641.1 - 1.4e-14 54.2 0.0 2.9e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ctf8 PF09696.10 CCD24642.1 - 3.7e-23 82.4 0.5 3.4e-16 59.8 0.0 2.1 1 1 1 2 2 2 2 Ctf8 zinc_ribbon_10 PF10058.9 CCD24643.1 - 1.8e-14 53.2 1.2 4.3e-14 52.0 1.2 1.7 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF4271 PF14093.6 CCD24643.1 - 0.0003 20.8 0.2 0.00053 20.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) End3 PF12761.7 CCD24643.1 - 0.0009 19.5 0.5 0.0009 19.5 0.5 2.8 3 0 0 3 3 3 1 Actin cytoskeleton-regulatory complex protein END3 LPG_synthase_TM PF03706.13 CCD24643.1 - 0.032 13.8 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region DUF3792 PF12670.7 CCD24643.1 - 0.035 14.3 0.3 0.055 13.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Wzy_C PF04932.15 CCD24643.1 - 0.054 13.1 0.6 0.11 12.2 0.6 1.6 1 1 0 1 1 1 0 O-Antigen ligase TF_Zn_Ribbon PF08271.12 CCD24643.1 - 0.077 12.5 4.2 0.22 11.1 4.2 1.9 1 1 0 1 1 1 0 TFIIB zinc-binding PrgI PF12666.7 CCD24643.1 - 0.16 12.7 0.0 0.29 11.9 0.0 1.3 1 0 0 1 1 1 0 PrgI family protein Allexi_40kDa PF05549.11 CCD24643.1 - 0.25 10.8 5.3 4 6.9 0.4 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein Cep57_CLD_2 PF14197.6 CCD24643.1 - 0.43 10.7 12.0 0.3 11.2 6.9 2.9 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF489 PF04356.12 CCD24643.1 - 1.1 9.2 5.7 2.2 8.3 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF489) DUF4140 PF13600.6 CCD24643.1 - 1.3 9.5 3.9 12 6.5 0.1 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DNA_repr_REX1B PF14966.6 CCD24643.1 - 2.1 9.1 7.4 3.9 8.2 0.4 2.3 2 0 0 2 2 2 0 DNA repair REX1-B USP8_interact PF08941.10 CCD24643.1 - 2.8 7.7 6.4 4.6 7.0 0.0 3.1 3 1 1 4 4 4 0 USP8 interacting CTU2 PF10288.9 CCD24643.1 - 5.1 7.4 8.2 18 5.6 8.2 2.2 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Exonuc_VII_L PF02601.15 CCD24643.1 - 9.8 5.6 11.0 84 2.6 11.1 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit NAC PF01849.18 CCD24644.1 - 1.9e-16 59.8 0.8 1e-15 57.4 0.2 2.1 2 0 0 2 2 2 1 NAC domain UBA_4 PF14555.6 CCD24644.1 - 0.021 14.6 0.6 0.045 13.6 0.0 1.9 2 0 0 2 2 2 0 UBA-like domain MDM31_MDM32 PF08118.11 CCD24645.1 - 1.5e-215 716.9 6.6 2.2e-215 716.3 6.6 1.2 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins DUF218 PF02698.17 CCD24646.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 DUF218 domain RIX1 PF08167.12 CCD24647.1 - 2.4e-51 174.2 4.3 2.4e-51 174.2 4.3 2.1 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis DUF281 PF03436.13 CCD24647.1 - 0.055 13.9 0.5 0.13 12.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF281) Chalcone_2 PF16035.5 CCD24648.1 - 1.1e-62 211.5 0.0 1.8e-62 210.7 0.0 1.4 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 CCD24648.1 - 0.015 15.4 6.0 0.045 13.9 0.3 2.8 2 1 0 3 3 3 0 Chalcone isomerase-like Glyco_hydro_79n PF03662.14 CCD24648.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain VWA_2 PF13519.6 CCD24649.1 - 5.9e-18 65.5 0.0 5.9e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 CCD24649.1 - 8.9e-05 22.8 0.5 0.00015 22.0 0.5 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 CCD24649.1 - 0.00021 21.2 0.3 0.00033 20.5 0.3 1.3 1 0 0 1 1 1 1 Ssl1-like Serine_rich PF08824.10 CCD24649.1 - 0.0057 16.7 0.1 0.0057 16.7 0.1 1.8 2 0 0 2 2 2 1 Serine rich protein interaction domain DUF5308 PF17233.2 CCD24649.1 - 0.013 15.7 2.7 0.022 15.0 2.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Presenilin PF01080.17 CCD24649.1 - 0.02 13.7 3.2 0.023 13.5 3.2 1.2 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CCD24649.1 - 4.8 6.7 28.2 8.9 5.8 28.2 1.4 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 CCD24649.1 - 5.1 8.1 11.9 9.7 7.2 11.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Homoserine_dh PF00742.19 CCD24650.1 - 7.7e-54 182.2 0.1 1.1e-53 181.8 0.1 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 CCD24650.1 - 7.1e-23 81.5 0.0 1.4e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CCD24650.1 - 0.025 15.1 0.0 0.1 13.2 0.0 2.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Nop PF01798.18 CCD24650.1 - 0.099 12.1 0.0 0.26 10.7 0.0 1.6 2 0 0 2 2 2 0 snoRNA binding domain, fibrillarin DHHA2 PF02833.14 CCD24651.1 - 6.2e-29 101.0 0.2 9.3e-29 100.4 0.2 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 CCD24651.1 - 1.5e-10 41.2 0.3 4.1e-10 39.8 0.1 1.9 2 0 0 2 2 2 1 DHH family CWC25 PF12542.8 CCD24651.1 - 0.02 15.8 0.0 0.045 14.6 0.0 1.5 1 0 0 1 1 1 0 Pre-mRNA splicing factor Mgm101p PF06420.12 CCD24652.1 - 4.3e-84 280.2 0.2 9.2e-84 279.1 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial genome maintenance MGM101 CHASE5 PF17149.4 CCD24652.1 - 0.032 14.2 0.0 0.24 11.3 0.0 2.2 1 1 1 2 2 2 0 Periplasmic sensor domain found in signal transduction proteins SprA-related PF12118.8 CCD24652.1 - 2 7.5 11.2 2.6 7.1 11.2 1.1 1 0 0 1 1 1 0 SprA-related family 5_nucleotid_C PF02872.18 CCD24653.1 - 0.02 15.1 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Ribosomal_S4e PF00900.20 CCD24654.1 - 7.2e-39 131.5 1.0 5.9e-38 128.6 0.7 2.1 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 CCD24654.1 - 1.4e-25 88.7 0.0 2.8e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CCD24654.1 - 2.4e-19 69.2 6.9 2.4e-19 69.2 6.9 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 CCD24654.1 - 4.2e-08 32.8 0.6 8.5e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 CCD24654.1 - 4.1e-06 26.5 1.8 4.1e-06 26.5 1.8 3.0 4 0 0 4 4 4 1 KOW motif dCache_2 PF08269.11 CCD24654.1 - 0.04 13.1 0.1 0.14 11.4 0.0 1.8 1 1 1 2 2 2 0 Cache domain Glyco_hydro_47 PF01532.20 CCD24655.1 - 9.2e-111 370.9 0.0 1.1e-110 370.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.25 CCD24656.1 - 1.5e-67 227.8 0.0 4.6e-67 226.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24656.1 - 3.8e-31 108.3 0.0 1.4e-30 106.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.24 CCD24656.1 - 8.6e-11 42.4 1.2 8.6e-11 42.4 1.2 2.8 3 0 0 3 3 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 CCD24656.1 - 4.1e-09 36.2 0.0 2e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 CCD24656.1 - 4.3e-09 36.6 4.8 9.7e-06 25.8 0.7 2.8 3 0 0 3 3 3 2 C2 domain Haspin_kinase PF12330.8 CCD24656.1 - 0.0032 16.4 9.3 0.22 10.4 9.3 2.8 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CCD24656.1 - 0.016 14.0 0.8 4.5 6.0 0.3 2.4 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 CCD24656.1 - 0.019 14.6 0.2 0.67 9.5 0.1 2.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 CCD24656.1 - 0.023 14.2 0.9 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Adeno_E3_15_3 PF03307.14 CCD24656.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region eIF3_p135 PF12807.7 CCD24656.1 - 0.52 10.3 5.5 0.088 12.8 0.9 2.0 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 HSF_DNA-bind PF00447.17 CCD24657.1 - 5.5e-31 107.0 1.5 1.3e-30 105.8 1.5 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 CCD24657.1 - 4.4e-28 97.7 0.6 9.2e-28 96.7 0.6 1.6 1 0 0 1 1 1 1 Response regulator receiver domain SHE3 PF17078.5 CCD24657.1 - 0.018 14.8 0.2 0.018 14.8 0.2 2.0 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 GyrB_insert PF18053.1 CCD24657.1 - 0.062 13.2 1.4 6 6.7 0.1 2.5 1 1 1 2 2 2 0 DNA gyrase B subunit insert domain SET PF00856.28 CCD24658.1 - 2.7e-15 57.2 0.8 3.2e-14 53.7 0.8 2.5 1 1 0 1 1 1 1 SET domain Myticin-prepro PF10690.9 CCD24658.1 - 0.007 16.6 2.2 1.9 8.8 0.2 2.7 2 0 0 2 2 2 2 Myticin pre-proprotein from the mussel LepA_C PF06421.12 CCD24658.1 - 0.096 12.8 0.5 0.21 11.8 0.5 1.5 1 0 0 1 1 1 0 GTP-binding protein LepA C-terminus DZR PF12773.7 CCD24658.1 - 3.4 7.8 8.2 0.14 12.2 1.6 2.1 2 0 0 2 2 2 0 Double zinc ribbon 4HBT PF03061.22 CCD24659.1 - 0.047 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily 5-FTHF_cyc-lig PF01812.20 CCD24660.1 - 2.3e-29 102.6 0.0 4.6e-29 101.6 0.0 1.5 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Aminotran_4 PF01063.19 CCD24661.1 - 1.2e-34 120.1 0.0 1.6e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Fungal_trans PF04082.18 CCD24662.1 - 1.5e-07 30.8 5.1 1.5e-07 30.8 5.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD24662.1 - 2.9e-06 27.3 7.6 6.4e-06 26.2 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 CCD24663.1 - 4.1e-12 46.4 0.6 0.01 16.7 0.0 4.9 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD24663.1 - 0.00031 21.0 0.0 3.9 7.8 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4738 PF15889.5 CCD24663.1 - 0.0086 15.9 0.8 0.12 12.2 0.0 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4738) F5_F8_type_C PF00754.25 CCD24663.1 - 0.062 13.4 0.3 0.13 12.4 0.3 1.6 1 0 0 1 1 1 0 F5/8 type C domain DUF1664 PF07889.12 CCD24664.1 - 0.0008 19.4 0.6 0.0061 16.6 0.1 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) COG5 PF10392.9 CCD24664.1 - 0.0024 18.1 5.5 0.099 12.8 0.2 3.1 2 1 1 3 3 3 2 Golgi transport complex subunit 5 Syntaxin-6_N PF09177.11 CCD24664.1 - 0.003 18.1 9.7 0.21 12.2 0.2 3.4 1 1 2 3 3 3 1 Syntaxin 6, N-terminal SKA2 PF16740.5 CCD24664.1 - 0.016 15.0 0.2 0.048 13.4 0.2 1.8 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 TMF_TATA_bd PF12325.8 CCD24664.1 - 0.04 14.1 4.0 0.25 11.6 0.2 2.9 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 CCD24664.1 - 0.043 13.9 1.4 0.085 12.9 0.1 2.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein ABC_tran_CTD PF16326.5 CCD24664.1 - 0.066 13.5 2.6 2.4 8.5 0.0 3.2 3 0 0 3 3 3 0 ABC transporter C-terminal domain CLZ PF16526.5 CCD24664.1 - 0.093 13.1 0.1 0.093 13.1 0.1 2.7 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sec34 PF04136.15 CCD24664.1 - 0.14 12.1 5.6 0.17 11.8 1.1 2.6 2 1 0 3 3 3 0 Sec34-like family Baculo_PEP_C PF04513.12 CCD24664.1 - 0.25 11.4 13.6 0.12 12.4 4.4 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Takusan PF04822.13 CCD24664.1 - 0.26 11.2 6.9 0.13 12.2 1.6 2.7 3 0 0 3 3 3 0 Takusan APG17 PF04108.12 CCD24664.1 - 0.48 9.5 8.4 0.6 9.2 6.6 2.0 1 1 0 1 1 1 0 Autophagy protein Apg17 Swi5 PF07061.11 CCD24664.1 - 1.2 9.3 6.9 2.2 8.4 0.7 2.8 3 0 0 3 3 2 0 Swi5 LMBR1 PF04791.16 CCD24664.1 - 3.2 6.6 4.9 4 6.2 4.9 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein DASH_Dad3 PF08656.10 CCD24664.1 - 5.2 7.2 9.0 0.66 10.1 0.9 3.0 2 1 1 3 3 3 0 DASH complex subunit Dad3 Cation_ATPase_C PF00689.21 CCD24665.1 - 1.8e-42 145.1 4.7 1.8e-42 145.1 4.7 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CCD24665.1 - 1.6e-39 135.3 0.7 1.6e-39 135.3 0.7 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 CCD24665.1 - 5.2e-16 58.5 0.0 1.4e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CCD24665.1 - 8.3e-16 58.9 0.1 2e-12 47.8 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CCD24665.1 - 2.5e-07 30.3 0.0 9e-07 28.5 0.0 2.0 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CCD24665.1 - 0.00081 19.2 0.3 0.00081 19.2 0.3 3.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF1980 PF09323.10 CCD24665.1 - 6.5 6.6 9.1 2.6 7.9 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF1980) E1-E2_ATPase PF00122.20 CCD24666.1 - 2e-48 164.3 4.9 8.3e-48 162.3 3.8 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CCD24666.1 - 1.4e-19 71.3 0.1 4e-19 69.7 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CCD24666.1 - 1.7e-10 40.4 0.2 5.6e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CCD24666.1 - 0.0022 18.1 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CCD24666.1 - 0.0024 17.6 0.1 0.0046 16.7 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SIS_2 PF13580.6 CCD24666.1 - 0.037 14.1 0.1 0.62 10.1 0.0 2.5 2 0 0 2 2 2 0 SIS domain PUF PF00806.19 CCD24667.1 - 4e-65 212.0 14.5 2.6e-09 36.3 0.3 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 CCD24667.1 - 0.00038 20.8 1.3 0.42 11.0 0.1 3.6 3 2 0 3 3 3 2 CPL (NUC119) domain Fungal_trans PF04082.18 CCD24668.1 - 1.9e-29 102.5 1.6 1.9e-29 102.5 1.6 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD24668.1 - 3.7e-07 30.2 16.7 7.3e-07 29.2 16.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HypA PF01155.19 CCD24668.1 - 5.8 7.0 6.3 79 3.3 5.1 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Fungal_trans PF04082.18 CCD24669.1 - 2.7e-29 102.0 3.5 2.7e-29 102.0 3.5 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD24669.1 - 9.8e-08 32.0 15.4 2.2e-07 30.9 15.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.26 CCD24670.1 - 4e-33 114.5 0.1 4.5e-33 114.3 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF962 PF06127.11 CCD24671.1 - 1.8e-26 92.1 0.8 3.7e-26 91.1 0.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Phage_holin_4_2 PF04020.13 CCD24671.1 - 2 9.1 9.5 0.26 12.0 5.7 1.4 2 0 0 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV Aconitase PF00330.20 CCD24672.1 - 1.1e-158 529.1 0.0 1.4e-158 528.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCD24672.1 - 1.1e-44 151.9 0.0 2.1e-44 151.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain ATE_C PF04377.15 CCD24674.1 - 1.2e-40 139.3 0.2 2.6e-40 138.2 0.2 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 CCD24674.1 - 1.4e-25 89.5 2.5 3e-25 88.4 2.5 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus HSCB_C PF07743.13 CCD24675.1 - 4e-20 72.1 7.0 2.9e-19 69.3 3.0 2.3 2 0 0 2 2 2 2 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CCD24675.1 - 2.5e-08 33.9 0.8 2.5e-08 33.9 0.8 2.9 2 1 1 3 3 3 1 DnaJ domain Cnl2_NKP2 PF09447.10 CCD24675.1 - 0.1 12.7 0.2 0.1 12.7 0.2 2.1 3 0 0 3 3 3 0 Cnl2/NKP2 family protein DUF5398 PF17376.2 CCD24675.1 - 0.17 12.5 3.1 0.3 11.7 1.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5398) CK_II_beta PF01214.18 CCD24676.1 - 1.9e-69 233.1 0.8 4.7e-69 231.8 0.8 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit DUF4530 PF15039.6 CCD24676.1 - 0.3 11.2 2.9 0.57 10.3 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) CHD5 PF04420.14 CCD24677.1 - 6e-49 165.9 4.4 7.7e-49 165.6 4.4 1.1 1 0 0 1 1 1 1 CHD5-like protein DUF16 PF01519.16 CCD24677.1 - 0.00092 19.7 3.3 0.00092 19.7 3.3 2.1 2 1 0 2 2 2 1 Protein of unknown function DUF16 DDE_Tnp_2 PF04693.12 CCD24677.1 - 0.0075 15.5 0.5 0.01 15.1 0.5 1.2 1 0 0 1 1 1 1 Archaeal putative transposase ISC1217 DivIC PF04977.15 CCD24677.1 - 0.79 9.5 8.4 1 9.2 3.2 2.4 1 1 1 2 2 2 0 Septum formation initiator STT3 PF02516.14 CCD24678.1 - 2.5e-149 498.3 48.0 5.8e-147 490.6 44.0 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit FYVE PF01363.21 CCD24679.1 - 6.6e-14 51.8 10.6 1.5e-13 50.6 10.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger NSs PF11073.8 CCD24680.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like Med3 PF11593.8 CCD24682.1 - 1.5e-146 488.7 47.4 1.7e-146 488.5 47.4 1.0 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DUF3682 PF12446.8 CCD24682.1 - 0.0018 18.8 17.6 0.0018 18.8 17.6 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3682) DUF3504 PF12012.8 CCD24682.1 - 0.21 11.5 0.1 0.21 11.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) FAM199X PF15814.5 CCD24682.1 - 0.29 10.2 4.5 0.43 9.6 4.5 1.2 1 0 0 1 1 1 0 Protein family FAM199X DUF3464 PF11947.8 CCD24682.1 - 1.6 8.5 6.5 4.8 6.9 6.5 1.8 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Ndc1_Nup PF09531.10 CCD24682.1 - 2.9 6.4 12.5 3.7 6.1 12.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Glyco_hydro_63 PF03200.16 CCD24683.1 - 8.5e-172 572.3 0.4 4e-171 570.1 0.4 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CCD24683.1 - 1.4e-63 215.1 0.2 2.1e-63 214.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 CCD24683.1 - 0.0014 17.7 0.0 0.0025 16.8 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase MHCassoc_trimer PF08831.10 CCD24683.1 - 0.022 14.8 0.0 0.11 12.5 0.0 2.3 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain DUF3841 PF12952.7 CCD24683.1 - 0.075 12.8 1.5 0.53 10.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3841) MMR1 PF08505.10 CCD24684.1 - 0.0026 18.1 22.0 0.004 17.5 22.0 1.2 1 0 0 1 1 1 1 Mitochondrial Myo2 receptor-related protein TFIIA PF03153.13 CCD24684.1 - 0.074 13.0 22.5 0.1 12.6 22.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CCD24684.1 - 0.35 10.8 10.3 0.54 10.2 10.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SOG2 PF10428.9 CCD24684.1 - 1.1 8.3 26.6 1.8 7.6 26.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SWI-SNF_Ssr4 PF08549.10 CCD24684.1 - 1.2 7.6 25.1 1.7 7.1 25.1 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Macoilin PF09726.9 CCD24684.1 - 1.6 7.2 17.4 2.2 6.8 17.4 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CCD24684.1 - 2.7 6.7 11.7 4.5 5.9 11.7 1.5 1 0 0 1 1 1 0 Presenilin Hamartin PF04388.12 CCD24684.1 - 5.6 5.5 21.8 7 5.2 21.8 1.1 1 0 0 1 1 1 0 Hamartin protein Ribosomal_L7Ae PF01248.26 CCD24685.1 - 3.7e-23 81.1 0.1 4.1e-23 80.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L24e PF01246.20 CCD24686.1 - 6.7e-30 103.1 0.2 6.7e-30 103.1 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e AGA2 PF17366.2 CCD24687.1 - 2.2e-26 91.3 9.7 2.7e-26 91.0 9.7 1.1 1 0 0 1 1 1 1 A-agglutinin-binding subunit Aga2 TMPIT PF07851.13 CCD24688.1 - 0.012 14.9 1.7 0.015 14.6 1.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF2887 PF11103.8 CCD24688.1 - 0.054 13.5 2.3 0.074 13.1 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) Terminase_3C PF17288.2 CCD24688.1 - 0.055 13.9 0.2 0.071 13.5 0.2 1.2 1 0 0 1 1 1 0 Terminase RNAseH like domain DUF5345 PF17280.2 CCD24688.1 - 0.085 12.8 2.3 3.1 7.8 0.3 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5345) Noelin-1 PF12308.8 CCD24688.1 - 0.4 10.7 2.4 1.3 9.1 2.5 1.8 1 1 1 2 2 2 0 Neurogenesis glycoprotein FapA PF03961.13 CCD24688.1 - 1.2 7.7 4.6 1.4 7.4 4.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-H2C2_2 PF13465.6 CCD24689.1 - 6.9e-07 29.4 11.1 0.0051 17.2 0.8 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CCD24689.1 - 1.2e-05 25.5 12.5 0.031 14.7 0.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD24689.1 - 0.0091 16.8 10.7 0.81 10.7 4.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger ADK_lid PF05191.14 CCD24689.1 - 0.056 13.4 1.3 0.15 12.1 1.3 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid zf-C2H2_6 PF13912.6 CCD24689.1 - 0.6 10.2 4.5 14 5.9 1.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 CCD24689.1 - 0.64 10.7 0.1 0.64 10.7 0.1 2.8 2 1 1 3 3 3 0 FOXP coiled-coil domain Ecl1 PF12855.7 CCD24690.1 - 5.3e-08 34.2 13.7 2.9e-06 28.6 2.6 2.9 1 1 1 2 2 2 2 ECL1/2/3 zinc binding proteins DUF3612 PF12268.8 CCD24690.1 - 0.043 13.9 0.8 0.059 13.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) zf-FCS PF06467.14 CCD24690.1 - 0.056 13.4 1.7 0.13 12.2 1.7 1.6 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF2116 PF09889.9 CCD24690.1 - 0.3 11.1 2.3 0.68 10.0 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) NUC153 PF08159.12 CCD24692.1 - 3.5e-11 42.7 3.3 8e-11 41.6 3.3 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 CCD24692.1 - 0.00044 21.0 0.5 5.5 8.0 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD24692.1 - 0.16 12.3 0.0 2.1 8.7 0.0 2.6 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Chloroplast_duf PF14476.6 CCD24693.1 - 2.1 7.2 4.7 9.7 5.1 0.1 2.3 2 0 0 2 2 2 0 Petal formation-expressed Isochorismatase PF00857.20 CCD24694.1 - 4.7e-27 95.3 0.0 6.8e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family MRP-S34 PF16053.5 CCD24694.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S34 Gly_transf_sug PF04488.15 CCD24695.1 - 2.4e-15 56.9 0.2 7.5e-15 55.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif SCF PF02404.15 CCD24695.1 - 0.011 15.1 0.6 0.023 14.1 0.6 1.4 1 0 0 1 1 1 0 Stem cell factor Ras PF00071.22 CCD24696.1 - 1.2e-50 171.3 0.1 1.6e-50 170.9 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD24696.1 - 2.9e-17 63.0 0.0 5.7e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD24696.1 - 2.6e-08 33.5 0.1 3.5e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CCD24696.1 - 7.1e-06 25.7 0.1 1.5e-05 24.7 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCD24696.1 - 0.0012 18.8 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CCD24696.1 - 0.0035 17.4 0.0 0.0067 16.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RESP18 PF14948.6 CCD24696.1 - 0.041 14.2 2.4 0.063 13.6 0.8 1.9 1 1 1 2 2 2 0 RESP18 domain PRC2_HTH_1 PF18118.1 CCD24696.1 - 0.19 12.5 2.0 0.59 11.0 2.0 1.8 1 1 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain ALAD PF00490.21 CCD24697.1 - 2.9e-120 401.2 0.0 3.4e-120 401.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Pyridox_oxase_2 PF12766.7 CCD24698.1 - 2.2e-30 105.2 0.1 4.5e-30 104.2 0.1 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Aminotran_3 PF00202.21 CCD24699.1 - 6.7e-100 334.6 0.0 7.7e-100 334.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III ATP-synt_F PF01990.17 CCD24700.1 - 1.3e-31 108.8 0.1 1.4e-31 108.6 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.6 CCD24700.1 - 0.062 12.5 0.0 0.065 12.4 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DUF2251 PF10008.9 CCD24700.1 - 0.082 13.0 0.1 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2251) Transcrip_reg PF01709.20 CCD24701.1 - 6.9e-62 209.0 4.5 9.8e-62 208.5 4.5 1.2 1 0 0 1 1 1 1 Transcriptional regulator LPP20 PF02169.16 CCD24701.1 - 0.02 15.2 0.6 0.051 13.9 0.6 1.7 1 0 0 1 1 1 0 LPP20 lipoprotein Mid2 PF04478.12 CCD24702.1 - 1.7e-65 219.4 2.8 1.7e-65 219.4 2.8 4.2 3 2 2 5 5 5 1 Mid2 like cell wall stress sensor Thg1 PF04446.12 CCD24704.1 - 5.9e-51 171.7 0.6 8.1e-51 171.3 0.6 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 CCD24704.1 - 1e-36 125.8 0.1 2e-36 124.8 0.1 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain PhoR PF11808.8 CCD24705.1 - 0.081 13.4 0.1 0.081 13.4 0.1 3.1 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR UPF0121 PF03661.13 CCD24705.1 - 0.24 10.7 13.9 0.022 14.1 6.5 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0121) Ribosomal_S25 PF03297.15 CCD24706.1 - 1.9e-39 133.9 7.0 2.2e-39 133.7 7.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FtsK_gamma PF09397.10 CCD24706.1 - 0.00026 20.7 0.1 0.0004 20.1 0.1 1.3 1 0 0 1 1 1 1 Ftsk gamma domain EAP30 PF04157.16 CCD24706.1 - 0.032 13.5 0.1 0.037 13.3 0.1 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_CodY PF08222.11 CCD24706.1 - 0.036 13.6 0.1 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_DeoR PF08220.12 CCD24706.1 - 0.082 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain AAA PF00004.29 CCD24707.1 - 2.2e-36 125.2 0.0 3.5e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCD24707.1 - 3.9e-12 45.8 0.4 1e-11 44.4 0.4 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CCD24707.1 - 5.8e-06 26.3 0.4 0.00011 22.2 0.4 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CCD24707.1 - 1.2e-05 25.1 0.0 3.9e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CCD24707.1 - 1.3e-05 25.2 0.0 3.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CCD24707.1 - 1.6e-05 25.1 0.0 3.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CCD24707.1 - 1.8e-05 25.0 0.9 0.0043 17.3 0.2 3.2 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCD24707.1 - 4.5e-05 23.9 0.4 0.0018 18.7 0.0 2.5 2 1 0 3 3 2 1 AAA ATPase domain AAA_33 PF13671.6 CCD24707.1 - 0.0002 21.5 0.0 0.00065 19.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CCD24707.1 - 0.00044 20.0 0.0 0.00085 19.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CCD24707.1 - 0.0013 18.2 0.1 0.0026 17.2 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CCD24707.1 - 0.0014 19.1 0.0 0.0038 17.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 CCD24707.1 - 0.0021 18.4 0.0 0.0054 17.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 CCD24707.1 - 0.0026 17.4 0.1 0.0063 16.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CCD24707.1 - 0.0028 17.6 0.0 0.0071 16.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Sigma54_activ_2 PF14532.6 CCD24707.1 - 0.0035 17.5 0.0 0.0071 16.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.6 CCD24707.1 - 0.0061 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 CCD24707.1 - 0.0064 15.9 0.0 2.8 7.3 0.0 2.4 1 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 CCD24707.1 - 0.0084 15.6 0.1 0.031 13.8 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region Rad17 PF03215.15 CCD24707.1 - 0.011 15.6 0.4 0.083 12.8 0.0 2.4 2 2 0 2 2 2 0 Rad17 P-loop domain Bac_DnaA PF00308.18 CCD24707.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein Hydin_ADK PF17213.3 CCD24707.1 - 0.016 15.5 0.1 2.7 8.2 0.1 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain KAP_NTPase PF07693.14 CCD24707.1 - 0.027 13.7 1.3 4 6.6 0.0 2.8 2 1 1 3 3 3 0 KAP family P-loop domain ATPase PF06745.13 CCD24707.1 - 0.042 13.2 0.0 0.22 10.8 0.0 2.0 1 1 1 2 2 2 0 KaiC TsaE PF02367.17 CCD24707.1 - 0.044 13.8 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CCD24707.1 - 0.046 12.9 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 CCD24707.1 - 0.047 13.6 0.4 0.3 11.0 0.0 2.2 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 CCD24707.1 - 0.048 13.9 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DNA_topoisoIV PF00521.20 CCD24707.1 - 0.06 12.2 0.0 0.13 11.1 0.0 1.5 1 1 1 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A AAA_17 PF13207.6 CCD24707.1 - 0.077 13.4 0.0 0.23 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CCD24707.1 - 0.081 12.6 0.0 0.32 10.7 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CCD24707.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 CCD24707.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Evr1_Alr PF04777.13 CCD24708.1 - 1.4e-28 99.2 4.5 2.3e-28 98.6 4.5 1.3 1 0 0 1 1 1 1 Erv1 / Alr family SNAD4 PF18750.1 CCD24708.1 - 0.093 12.9 0.3 0.17 12.1 0.1 1.6 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 Alba PF01918.21 CCD24709.1 - 1.3e-06 28.1 0.0 2.2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Alba Ribosomal_L10 PF00466.20 CCD24710.1 - 1.4e-23 82.9 0.2 2.3e-23 82.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 CCD24710.1 - 1.8e-21 75.9 0.0 3e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 CCD24710.1 - 5.6e-18 65.3 2.3 5.6e-18 65.3 2.3 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Alg14 PF08660.11 CCD24710.1 - 0.11 12.4 0.0 0.51 10.2 0.0 1.9 2 0 0 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like Abhydrolase_1 PF00561.20 CCD24711.1 - 3.6e-17 62.9 0.0 1e-16 61.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCD24711.1 - 1.4e-11 45.4 0.0 3.9e-11 44.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCD24711.1 - 9.7e-11 41.4 0.0 1.3e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CCD24711.1 - 0.0053 16.5 2.4 0.29 10.8 2.4 2.9 1 1 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 CCD24711.1 - 0.037 13.6 0.2 0.29 10.7 0.1 2.1 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase Glucan_synthase PF02364.15 CCD24712.1 - 0 1261.5 0.0 0 1260.7 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CCD24712.1 - 6.5e-42 142.9 1.0 6.5e-42 142.9 1.0 2.2 2 1 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 TIM21 PF08294.11 CCD24713.1 - 2e-56 189.9 0.0 2.8e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 TIM21 Ribosomal_L26 PF16906.5 CCD24714.1 - 1.7e-37 127.7 1.5 2.1e-37 127.4 1.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CCD24714.1 - 0.00049 20.0 1.6 0.00058 19.7 0.5 1.7 2 0 0 2 2 2 1 KOW motif 6PF2K PF01591.18 CCD24715.1 - 1.5e-54 184.7 4.1 2.1e-54 184.2 4.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CCD24715.1 - 4.2e-13 49.4 0.0 7.8e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CCD24715.1 - 0.00029 21.0 0.0 0.00062 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Colicin PF01024.19 CCD24715.1 - 0.078 12.9 0.4 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Colicin pore forming domain Glycohydro_20b2 PF14845.6 CCD24715.1 - 0.12 13.1 0.0 7.9 7.1 0.0 2.4 2 1 0 2 2 2 0 beta-acetyl hexosaminidase like PAP2 PF01569.21 CCD24716.1 - 4.1e-19 68.7 1.0 4.1e-19 68.7 1.0 1.6 2 0 0 2 2 2 1 PAP2 superfamily MFS_1 PF07690.16 CCD24716.1 - 0.021 13.8 8.2 0.028 13.3 8.2 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF212 PF02681.14 CCD24716.1 - 0.028 14.6 0.0 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 Divergent PAP2 family UPF0542 PF15086.6 CCD24716.1 - 0.028 14.3 0.4 0.076 13.0 0.4 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 KleE PF17394.2 CCD24716.1 - 0.26 11.5 9.3 3.5 7.9 1.1 2.6 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein ACBP PF00887.19 CCD24717.1 - 9e-30 102.7 1.4 9.8e-30 102.6 1.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 CCD24717.1 - 0.0047 17.3 0.2 0.065 13.6 0.0 1.9 1 1 1 2 2 2 1 FERM central domain ORMDL PF04061.14 CCD24718.1 - 1.3e-57 193.4 5.4 1.7e-57 193.0 5.4 1.2 1 0 0 1 1 1 1 ORMDL family PI3K_C2 PF00792.24 CCD24718.1 - 0.033 14.1 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 SCIMP PF15050.6 CCD24718.1 - 4.6 7.7 6.2 0.61 10.5 2.1 1.7 1 1 1 2 2 2 0 SCIMP protein Pkinase PF00069.25 CCD24719.1 - 3.1e-67 226.7 0.0 3.8e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24719.1 - 4.6e-34 117.9 0.1 7.6e-34 117.2 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD24719.1 - 7.4e-05 22.2 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CCD24719.1 - 0.00076 18.9 0.2 0.004 16.5 0.2 1.9 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CCD24719.1 - 0.0015 17.6 0.2 0.0025 16.8 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CCD24719.1 - 0.016 15.1 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CCD24719.1 - 0.029 14.0 0.1 0.058 13.0 0.1 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CCD24719.1 - 0.041 13.5 0.1 0.067 12.8 0.1 1.3 1 0 0 1 1 1 0 RIO1 family DUF2439 PF10382.9 CCD24721.1 - 6.2e-17 61.7 0.1 1.2e-16 60.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) TAL_FSA PF00923.19 CCD24722.1 - 2e-90 303.0 1.4 2.3e-90 302.8 1.4 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DUF5590 PF17881.1 CCD24722.1 - 0.012 15.6 0.6 0.044 13.9 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5590) zf-C2H2 PF00096.26 CCD24723.1 - 0.00024 21.4 12.8 0.01 16.2 0.1 4.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 CCD24723.1 - 0.0018 18.0 2.5 3.1 7.7 0.0 3.4 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 CCD24723.1 - 0.72 10.8 15.9 0.74 10.8 0.1 4.8 5 1 0 5 5 5 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCD24723.1 - 0.81 10.2 17.8 13 6.4 0.1 4.8 4 1 0 4 4 4 0 Zinc-finger double domain zf-C2H2_aberr PF17017.5 CCD24723.1 - 4.8 7.3 11.5 3.1 7.9 0.4 2.7 3 0 0 3 3 3 0 Aberrant zinc-finger Pkinase PF00069.25 CCD24725.1 - 2.5e-51 174.6 0.1 3.1e-51 174.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24725.1 - 3.8e-28 98.5 0.0 5.7e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCD24725.1 - 3.9e-07 30.2 0.0 0.018 15.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CCD24725.1 - 8.7e-07 28.5 0.0 2.5e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CCD24725.1 - 0.032 13.6 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CCD24725.1 - 0.084 11.6 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RXT2_N PF08595.11 CCD24725.1 - 0.084 12.9 0.4 0.2 11.6 0.4 1.7 1 1 0 1 1 1 0 RXT2-like, N-terminal SR-25 PF10500.9 CCD24725.1 - 9 5.8 13.2 16 5.0 13.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MMU163 PF17119.5 CCD24726.1 - 2.5e-19 69.4 1.0 1.1e-18 67.3 1.0 1.8 1 1 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis GDE_C PF06202.14 CCD24726.1 - 0.042 12.8 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Bromodomain PF00439.25 CCD24727.1 - 1.2e-26 92.5 8.6 2.2e-14 53.3 2.1 2.8 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 CCD24727.1 - 2.4e-23 82.3 0.0 5.8e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 BAH domain Folliculin PF11704.8 CCD24728.1 - 1.9e-47 161.5 0.3 2.9e-47 160.9 0.3 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport DUF2321 PF10083.9 CCD24728.1 - 0.0082 15.8 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2321) EF-hand_7 PF13499.6 CCD24729.1 - 1.3e-09 38.3 3.1 4e-05 24.0 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCD24729.1 - 3.9e-08 32.6 0.6 0.045 13.7 0.0 4.3 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CCD24729.1 - 6.3e-07 28.5 0.0 4.6 7.0 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CCD24729.1 - 0.0049 16.7 0.1 10 6.1 0.0 3.9 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 CCD24729.1 - 0.017 14.6 0.1 27 4.5 0.0 3.7 4 0 0 4 4 4 0 EF hand FAM75 PF14650.6 CCD24729.1 - 2.3 7.7 19.3 3.7 7.0 19.3 1.2 1 0 0 1 1 1 0 FAM75 family Septin PF00735.18 CCD24730.1 - 1.5e-85 286.9 3.1 2.9e-85 286.0 3.1 1.5 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 CCD24730.1 - 1.9e-05 24.6 0.9 0.00074 19.5 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CCD24730.1 - 0.00083 18.9 2.0 0.57 9.7 0.2 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CCD24730.1 - 0.00087 19.7 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 CCD24730.1 - 0.0021 18.1 0.1 0.0059 16.7 0.1 1.8 2 0 0 2 2 1 1 50S ribosome-binding GTPase T2SSE PF00437.20 CCD24730.1 - 0.0022 17.1 0.1 0.0038 16.3 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 CCD24730.1 - 0.0038 17.5 0.3 0.012 15.8 0.3 2.0 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 CCD24730.1 - 0.005 16.6 0.1 0.0086 15.8 0.1 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.6 CCD24730.1 - 0.0096 15.7 0.0 0.025 14.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 CCD24730.1 - 0.013 14.9 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 CCD24730.1 - 0.028 14.9 2.1 0.047 14.2 0.8 1.9 1 1 0 1 1 1 0 ABC transporter Roc PF08477.13 CCD24730.1 - 0.029 14.6 0.1 0.099 12.9 0.1 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 CCD24730.1 - 0.031 14.3 0.2 1.4 8.9 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 CCD24730.1 - 0.036 13.8 0.1 0.081 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PIF1 PF05970.14 CCD24730.1 - 0.043 13.0 4.7 0.23 10.6 0.0 3.2 4 0 0 4 4 4 0 PIF1-like helicase DUF2075 PF09848.9 CCD24730.1 - 0.048 12.9 1.3 0.092 12.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.23 CCD24730.1 - 0.049 13.7 2.3 0.95 9.5 0.2 2.8 2 1 1 3 3 3 0 Dynamin family AIG1 PF04548.16 CCD24730.1 - 0.053 12.8 0.4 0.053 12.8 0.4 2.2 2 0 0 2 2 2 0 AIG1 family ATP_bind_1 PF03029.17 CCD24730.1 - 0.092 12.5 0.2 16 5.2 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ras PF00071.22 CCD24730.1 - 0.1 12.2 1.0 0.2 11.2 0.1 2.0 2 0 0 2 2 1 0 Ras family AAA PF00004.29 CCD24730.1 - 0.1 13.0 0.1 0.34 11.3 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) FA_hydroxylase PF04116.13 CCD24731.1 - 4.4e-25 88.6 20.3 4.4e-25 88.6 20.3 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily GATase_5 PF13507.6 CCD24732.1 - 4.6e-100 334.0 0.1 7e-100 333.4 0.1 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 CCD24732.1 - 1.5e-40 138.9 0.1 8.4e-28 97.5 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 CCD24732.1 - 4.7e-25 87.8 0.0 8.7e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 CCD24732.1 - 7.8e-23 80.8 0.0 2.7e-22 79.0 0.0 2.0 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain DUF2462 PF09495.10 CCD24733.1 - 6.2e-16 58.9 13.5 8.2e-16 58.5 13.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) ECH_2 PF16113.5 CCD24733.1 - 0.14 11.7 1.7 0.15 11.6 1.7 1.0 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase 60KD_IMP PF02096.20 CCD24734.1 - 6.3e-10 39.2 9.8 8e-10 38.9 1.7 2.3 2 0 0 2 2 2 2 60Kd inner membrane protein Spt4 PF06093.13 CCD24735.1 - 1.7e-24 85.7 0.0 2e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger MFS_1 PF07690.16 CCD24736.1 - 9e-18 64.3 17.2 9e-18 64.3 17.2 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Ribosomal_S8 PF00410.19 CCD24737.1 - 1.3e-24 86.6 0.2 2.2e-24 85.8 0.2 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 zf-H2C2_2 PF13465.6 CCD24738.1 - 7e-05 23.1 1.8 7e-05 23.1 1.8 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 CCD24738.1 - 0.0002 21.6 11.6 0.049 14.1 1.9 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD24738.1 - 0.011 16.5 11.1 0.61 11.1 2.4 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3989 PF13150.6 CCD24738.1 - 0.057 13.2 0.4 1.8 8.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) zf-C2H2_jaz PF12171.8 CCD24738.1 - 1.1 9.7 6.3 1.4 9.3 1.8 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Arrestin_C PF02752.22 CCD24739.1 - 3.8e-21 76.0 0.9 2.1e-20 73.5 0.3 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCD24739.1 - 1.5e-05 25.1 0.0 0.00063 19.8 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Pribosyltran_N PF13793.6 CCD24740.1 - 9.1e-41 138.4 0.1 5.9e-40 135.8 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CCD24740.1 - 2.7e-38 131.8 1.5 2.2e-30 106.1 0.3 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CCD24740.1 - 1.9e-07 30.7 0.2 0.00072 19.1 0.1 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain EBV-NA3 PF05009.12 CCD24740.1 - 0.46 10.0 1.8 0.84 9.1 1.8 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Vps39_1 PF10366.9 CCD24741.1 - 5.5e-24 84.5 0.2 5.5e-24 84.5 0.2 3.9 4 1 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 CCD24741.1 - 1.2e-09 38.6 0.6 5.1e-09 36.6 0.4 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 HSDR_N_2 PF13588.6 CCD24741.1 - 0.026 14.5 0.0 0.12 12.3 0.0 2.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) CTP_transf_3 PF02348.19 CCD24741.1 - 0.029 14.3 0.3 0.08 12.8 0.3 1.7 1 0 0 1 1 1 0 Cytidylyltransferase Rxt3 PF08642.10 CCD24742.1 - 3.5e-24 86.0 0.0 6.9e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 Ribosomal_L31e PF01198.19 CCD24743.1 - 6.6e-17 61.5 0.2 8.3e-17 61.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e BRE1 PF08647.11 CCD24744.1 - 4.7e-22 77.9 13.9 4.7e-22 77.9 13.9 6.7 4 2 2 6 6 6 2 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 CCD24744.1 - 8.5e-08 31.9 10.9 1.5e-07 31.2 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCD24744.1 - 1.6e-06 27.8 12.9 3e-06 27.0 12.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCD24744.1 - 4.8e-06 26.3 9.8 9.5e-06 25.4 9.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CCD24744.1 - 1.6e-05 24.8 13.2 3.2e-05 23.8 13.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CCD24744.1 - 6.1e-05 22.8 13.9 0.00013 21.8 13.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCD24744.1 - 0.00069 19.9 12.2 0.0013 19.1 12.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CCD24744.1 - 0.0022 18.0 10.2 0.0055 16.7 10.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger DivIC PF04977.15 CCD24744.1 - 0.0097 15.7 0.8 0.0097 15.7 0.8 7.2 4 2 3 7 7 7 1 Septum formation initiator zf-RING_6 PF14835.6 CCD24744.1 - 0.13 12.1 3.7 0.38 10.7 3.7 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CCD24744.1 - 0.71 9.7 10.7 1.5 8.7 10.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CCD24744.1 - 3.3 7.9 10.1 8 6.7 10.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FYVE PF01363.21 CCD24744.1 - 5.1 7.3 12.9 45 4.3 13.0 2.4 1 1 0 1 1 1 0 FYVE zinc finger DUF1765 PF08578.10 CCD24745.1 - 1.7e-17 64.1 13.6 1.7e-17 64.1 13.6 3.6 4 1 0 4 4 4 1 Protein of unknown function (DUF1765) APP_E2 PF12925.7 CCD24745.1 - 0.0086 15.8 0.2 0.026 14.3 0.2 1.8 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein zf-C2H2 PF00096.26 CCD24746.1 - 0.00044 20.5 17.1 0.076 13.5 1.1 4.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD24746.1 - 0.0023 18.6 17.4 0.063 14.2 0.6 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCD24746.1 - 0.0038 17.5 0.5 3.4 8.1 0.1 3.0 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CCD24746.1 - 0.17 12.4 15.4 0.19 12.2 1.0 3.3 3 0 0 3 3 3 0 Zinc-finger double domain Bap31 PF05529.12 CCD24747.1 - 4.5e-39 133.4 4.5 7.8e-39 132.6 4.5 1.4 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region DUF4094 PF13334.6 CCD24747.1 - 0.059 13.8 0.2 0.55 10.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Wzy_C PF04932.15 CCD24747.1 - 0.086 12.5 0.6 0.15 11.7 0.6 1.4 1 0 0 1 1 1 0 O-Antigen ligase COX6C PF02937.15 CCD24749.1 - 0.038 14.1 0.0 0.042 14.0 0.0 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Iso_dh PF00180.20 CCD24750.1 - 2e-70 237.7 0.0 2.3e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NTP_transf_6 PF06042.11 CCD24750.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase Pex19 PF04614.12 CCD24751.1 - 5.5e-54 183.5 20.2 5.5e-54 183.5 20.2 1.4 1 1 0 1 1 1 1 Pex19 protein family GET2 PF08690.10 CCD24751.1 - 6.9 6.2 32.9 1.1 8.8 9.2 2.7 1 1 1 3 3 3 0 GET complex subunit GET2 UQ_con PF00179.26 CCD24752.1 - 1.9e-44 150.7 0.1 2.2e-44 150.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCD24752.1 - 0.00021 21.0 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CCD24752.1 - 0.12 12.7 2.9 0.43 10.9 2.8 1.9 1 1 0 1 1 1 0 RWD domain Ribosomal_S14 PF00253.21 CCD24754.1 - 7.7e-15 54.4 3.6 8.5e-15 54.3 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.12 CCD24754.1 - 0.059 13.7 2.3 1 9.7 0.3 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Rad52_Rad22 PF04098.15 CCD24755.1 - 2.6e-43 147.6 2.4 6.1e-43 146.4 2.4 1.6 1 1 0 1 1 1 1 Rad52/22 family double-strand break repair protein Uso1_p115_head PF04869.14 CCD24756.1 - 9e-102 340.4 7.6 9e-102 340.4 7.6 2.4 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 CCD24756.1 - 9.3e-09 35.7 56.4 9.3e-09 35.7 56.4 15.6 2 1 10 12 12 12 2 Uso1 / p115 like vesicle tethering protein, C terminal region Golgin_A5 PF09787.9 CCD24756.1 - 0.0023 17.4 18.9 0.0023 17.4 18.9 9.8 2 2 7 9 9 9 4 Golgin subfamily A member 5 ATG16 PF08614.11 CCD24756.1 - 0.0054 17.0 21.8 0.0054 17.0 21.8 12.3 1 1 11 12 12 12 7 Autophagy protein 16 (ATG16) YdaT_toxin PF06254.11 CCD24756.1 - 0.077 13.6 0.8 1.9 9.1 0.1 3.8 3 0 0 3 3 3 0 Putative bacterial toxin ydaT Ank_5 PF13857.6 CCD24757.1 - 3.5e-16 59.1 0.1 1.6e-05 25.1 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCD24757.1 - 4.4e-15 55.8 1.6 1.2e-07 32.1 0.1 3.3 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCD24757.1 - 8.4e-13 48.7 0.1 5.2e-05 23.8 0.2 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CCD24757.1 - 1.5e-09 37.3 0.7 0.036 14.6 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CCD24757.1 - 7.3e-09 35.7 3.7 0.001 19.4 0.2 4.5 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 CCD24757.1 - 3.8e-08 33.1 1.8 1.3e-07 31.4 0.3 2.7 2 1 0 2 2 2 1 KilA-N domain DUF4061 PF13270.6 CCD24757.1 - 0.056 13.7 1.8 3.9 7.9 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Fib_alpha PF08702.10 CCD24757.1 - 0.11 12.6 3.4 0.34 11.1 3.4 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4446 PF14584.6 CCD24757.1 - 0.14 12.1 1.5 0.41 10.6 1.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) NTP_transferase PF00483.23 CCD24758.1 - 4.8e-54 183.6 0.0 6.2e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CCD24758.1 - 1.6e-10 40.3 7.5 2e-08 33.6 2.9 3.5 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CCD24758.1 - 5.3e-10 39.9 0.0 7e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CCD24758.1 - 0.00072 19.3 5.5 0.0024 17.6 0.7 3.1 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 CCD24758.1 - 0.021 13.0 0.6 0.031 12.4 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 CCD24758.1 - 0.027 13.4 0.0 0.21 10.5 0.1 2.0 2 0 0 2 2 2 0 L-fucokinase CTP_transf_3 PF02348.19 CCD24758.1 - 0.095 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase FA_hydroxylase PF04116.13 CCD24759.1 - 9.5e-26 90.7 22.5 9.5e-26 90.7 22.5 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.16 CCD24760.1 - 7.8e-11 41.5 28.2 2e-10 40.1 28.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily BCLP PF12304.8 CCD24760.1 - 0.44 10.1 7.4 0.7 9.4 3.8 2.7 2 0 0 2 2 2 0 Beta-casein like protein Acyltransferase PF01553.21 CCD24762.1 - 1.8e-33 115.0 0.0 2.7e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Glyco_trans_1_3 PF13528.6 CCD24762.1 - 0.091 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 1 GST_C_6 PF17171.4 CCD24762.1 - 0.11 12.3 0.1 0.41 10.5 0.1 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF5402 PF17393.2 CCD24762.1 - 0.13 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5402) La PF05383.17 CCD24763.1 - 6.1e-23 80.6 0.0 1.9e-22 79.0 0.0 1.9 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CCD24763.1 - 0.061 13.1 0.3 0.16 11.8 0.3 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SCVP PF17619.2 CCD24763.1 - 0.65 10.9 3.9 1.9 9.4 0.7 2.6 3 0 0 3 3 3 0 Secreted clade V proteins KRE9 PF05390.11 CCD24764.1 - 1.2e-51 173.7 8.6 2.7e-51 172.6 8.6 1.6 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 CCD24764.1 - 2.3e-10 41.1 0.3 2.3e-10 41.1 0.3 2.6 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family zf-C2H2_4 PF13894.6 CCD24765.1 - 5.4e-07 29.9 18.0 0.00051 20.7 0.7 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCD24765.1 - 0.00013 21.9 7.5 0.00042 20.2 0.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CCD24765.1 - 0.00045 20.5 20.6 0.00058 20.2 1.4 4.9 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CCD24765.1 - 0.00092 19.4 1.4 0.076 13.3 0.0 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CCD24765.1 - 0.072 13.4 5.7 0.044 14.1 1.9 2.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 CCD24765.1 - 0.11 12.4 4.4 2.6 8.0 0.1 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif zinc_ribbon_9 PF14369.6 CCD24765.1 - 0.12 12.7 4.7 5.9 7.2 0.2 3.5 3 0 0 3 3 3 0 zinc-ribbon zf-BED PF02892.15 CCD24766.1 - 1.5e-07 31.3 1.2 1.5e-07 31.3 1.2 2.0 2 0 0 2 2 2 1 BED zinc finger ELO PF01151.18 CCD24767.1 - 1.2e-58 198.6 28.1 1.4e-58 198.4 28.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family CNH PF00780.22 CCD24768.1 - 3.6e-78 263.0 0.3 3.3e-77 259.8 0.1 2.3 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 CCD24768.1 - 6.2e-39 133.2 0.0 6.2e-39 133.2 0.0 4.1 3 1 0 3 3 3 1 Pleckstrin homology domain RhoGEF PF00621.20 CCD24768.1 - 1.6e-29 103.4 0.0 1.6e-29 103.4 0.0 2.7 3 0 0 3 3 3 1 RhoGEF domain DEP PF00610.21 CCD24768.1 - 1.4e-13 50.7 0.0 3.1e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Voldacs PF03517.13 CCD24769.1 - 5.3e-22 78.4 0.0 9.5e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Orn_Arg_deC_N PF02784.16 CCD24770.1 - 4.9e-79 265.2 0.0 7.1e-79 264.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CCD24770.1 - 2.6e-16 59.6 0.0 5.3e-16 58.7 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain GATA PF00320.27 CCD24771.1 - 3.5e-08 32.9 8.1 1.2e-07 31.2 8.1 2.0 1 0 0 1 1 1 1 GATA zinc finger ACR_tran PF00873.19 CCD24771.1 - 2 5.9 3.9 3.1 5.3 3.9 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Mtr2 PF10429.9 CCD24772.1 - 1.8e-69 232.9 0.2 2.2e-69 232.6 0.2 1.0 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 SUR7 PF06687.12 CCD24773.1 - 4.4e-14 52.6 19.2 2e-13 50.4 19.2 2.0 1 1 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 CCD24773.1 - 9 6.2 22.2 15 5.5 1.2 2.5 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 ABC_membrane_2 PF06472.15 CCD24774.1 - 1.1e-65 221.8 9.6 1.1e-64 218.4 9.6 2.0 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CCD24774.1 - 3.8e-19 69.5 0.2 7.1e-17 62.2 0.2 2.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CCD24774.1 - 2.8e-05 24.1 0.1 2.8e-05 24.1 0.1 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 CCD24774.1 - 0.012 15.5 0.3 0.047 13.6 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 CCD24774.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CCD24774.1 - 0.069 13.4 0.0 0.71 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Mo25 PF08569.11 CCD24775.1 - 1.6e-110 369.6 15.7 2.6e-110 368.8 15.7 1.4 1 0 0 1 1 1 1 Mo25-like Bromodomain PF00439.25 CCD24776.1 - 4.1e-27 94.1 2.6 8.1e-27 93.1 2.6 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 CCD24776.1 - 2.2e-09 37.6 0.0 4.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCD24776.1 - 2.5e-06 27.5 0.0 5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCD24776.1 - 0.00037 20.8 0.1 0.00073 19.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain EF-hand_1 PF00036.32 CCD24777.1 - 1.2e-24 83.9 14.0 1.3e-05 24.4 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CCD24777.1 - 2.6e-21 75.9 6.3 2.3e-12 47.2 1.3 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCD24777.1 - 9.3e-20 68.8 7.5 0.00024 20.8 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CCD24777.1 - 1.5e-16 59.0 14.3 0.00071 19.0 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CCD24777.1 - 9.3e-10 38.2 13.3 0.0059 16.4 1.3 4.4 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CCD24777.1 - 9.9e-07 28.7 9.5 0.0045 16.9 0.2 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CCD24777.1 - 5.8e-06 26.6 0.2 0.1 12.9 0.1 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CCD24777.1 - 0.0044 17.3 0.1 4.2 7.8 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain Diphthamide_syn PF01866.17 CCD24778.1 - 1.9e-67 227.9 0.7 4.2e-67 226.7 0.7 1.6 1 1 0 1 1 1 1 Putative diphthamide synthesis protein Metallophos_2 PF12850.7 CCD24778.1 - 0.021 15.0 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain GST_N_4 PF17172.4 CCD24778.1 - 0.054 14.3 0.0 7.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Eaf7 PF07904.13 CCD24778.1 - 0.18 12.2 2.0 2.5 8.5 0.3 2.8 2 1 0 3 3 3 0 Chromatin modification-related protein EAF7 LRR_4 PF12799.7 CCD24779.1 - 2e-29 101.2 66.6 1.6e-08 34.7 2.8 7.0 1 1 9 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CCD24779.1 - 4.5e-21 74.4 32.7 3.4e-10 39.6 2.8 6.3 2 1 6 8 8 8 7 Leucine rich repeat LRR_9 PF14580.6 CCD24779.1 - 7.5e-16 58.1 24.7 3.6e-07 29.9 2.3 5.0 1 1 4 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 CCD24779.1 - 0.22 12.2 32.5 2.7 8.9 0.4 8.8 9 3 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 CCD24779.1 - 0.28 11.3 21.0 0.32 11.2 0.6 6.1 6 0 0 6 6 6 0 Leucine Rich repeat DUF3744 PF12558.8 CCD24779.1 - 1.2 10.0 13.4 7.2 7.5 1.7 4.2 3 2 1 4 4 4 0 ATP-binding cassette cobalt transporter DUF1884 PF08967.10 CCD24779.1 - 3.2 8.1 6.0 3.7 7.9 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1884) tRNA-synt_2b PF00587.25 CCD24780.1 - 9e-44 149.6 0.0 1.4e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CCD24780.1 - 5.9e-17 61.6 0.0 9.7e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain CHCH PF06747.13 CCD24781.1 - 5.1e-05 23.3 3.2 0.00012 22.2 3.2 1.6 1 0 0 1 1 1 1 CHCH domain Synaptobrevin PF00957.21 CCD24782.1 - 2.2e-15 56.2 1.2 3.7e-15 55.5 1.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CCD24782.1 - 5.8e-12 45.5 0.0 1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Fib_alpha PF08702.10 CCD24782.1 - 0.055 13.7 2.7 0.077 13.2 2.7 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Cyclase_polyket PF04673.12 CCD24782.1 - 0.073 13.3 0.4 0.84 9.9 0.0 2.3 1 1 2 3 3 3 0 Polyketide synthesis cyclase DUF3461 PF11944.8 CCD24782.1 - 0.076 13.1 3.2 0.072 13.2 2.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3461) FMN_dh PF01070.18 CCD24783.1 - 4.9e-118 394.1 0.0 5.9e-118 393.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CCD24783.1 - 3.6e-22 78.3 0.0 9.9e-22 76.9 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 CCD24783.1 - 7.8e-09 35.1 0.0 1.5e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 CCD24783.1 - 4.6e-05 23.0 0.0 7.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CCD24783.1 - 0.00025 20.1 0.9 0.0098 14.9 0.1 2.7 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 CCD24783.1 - 0.019 14.4 0.3 8.2 5.8 0.0 3.0 3 0 0 3 3 3 0 Histidine biosynthesis protein ThiG PF05690.14 CCD24783.1 - 0.094 12.0 0.0 3.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG FMN_dh PF01070.18 CCD24784.1 - 4.2e-118 394.3 0.0 5.1e-118 394.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CCD24784.1 - 2.9e-20 72.2 0.0 6e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 CCD24784.1 - 8.1e-09 35.1 0.0 1.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 CCD24784.1 - 0.00038 19.9 0.0 0.00061 19.3 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CCD24784.1 - 0.00083 18.5 2.8 0.0075 15.3 0.0 2.8 3 1 1 4 4 4 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 CCD24784.1 - 0.063 12.7 0.2 8.4 5.8 0.0 2.8 3 0 0 3 3 3 0 Histidine biosynthesis protein ThiG PF05690.14 CCD24784.1 - 0.2 10.9 0.3 7.3 5.8 0.1 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG SPC25 PF06703.11 CCD24785.1 - 1.3e-35 122.6 4.7 1.5e-35 122.4 4.7 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF1899 PF08953.11 CCD24786.1 - 4.5e-28 96.9 0.4 9.3e-28 95.9 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 CCD24786.1 - 1.2e-15 57.6 6.8 0.00018 22.2 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD24786.1 - 7.1e-05 23.0 0.1 0.0029 17.9 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCD24786.1 - 0.00017 20.4 0.1 0.0018 17.0 0.0 2.1 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CCD24786.1 - 0.0004 19.5 0.0 0.028 13.4 0.0 2.4 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_4 PF16300.5 CCD24786.1 - 0.00045 20.0 1.0 0.0012 18.7 1.0 1.8 1 1 0 1 1 1 1 Type of WD40 repeat eIF2A PF08662.11 CCD24786.1 - 0.032 14.1 1.6 2.4 8.0 0.1 3.4 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A DASH_Dad3 PF08656.10 CCD24786.1 - 0.039 14.0 0.4 0.13 12.4 0.4 1.8 1 0 0 1 1 1 0 DASH complex subunit Dad3 Fib_alpha PF08702.10 CCD24786.1 - 0.073 13.3 3.5 0.081 13.1 1.4 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IMPDH PF00478.25 CCD24787.1 - 4.9e-133 443.4 2.4 5.9e-133 443.2 2.4 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CCD24787.1 - 1.8e-14 53.9 0.0 9.4e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 CCD24787.1 - 1.3e-07 30.9 2.6 3.3e-07 29.6 2.6 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 CCD24787.1 - 3.3e-07 30.0 2.1 0.0016 17.9 1.1 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 CCD24787.1 - 0.0014 18.2 1.0 0.013 15.0 1.0 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein YpsA PF06908.11 CCD24787.1 - 0.01 15.8 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 YspA SLOG family ThiG PF05690.14 CCD24787.1 - 0.074 12.3 3.0 0.1 11.9 1.2 1.9 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG TFA2_Winged_2 PF18121.1 CCD24787.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 Hepar_II_III_N PF16889.5 CCD24788.1 - 0.0049 16.2 0.0 0.0054 16.0 0.0 1.1 1 0 0 1 1 1 1 Heparinase II/III N-terminus DUF2333 PF10095.9 CCD24788.1 - 0.091 11.8 0.5 0.93 8.4 0.5 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) PBP PF01161.20 CCD24790.1 - 3.5e-19 69.4 0.0 4.2e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein cNMP_binding PF00027.29 CCD24791.1 - 9.9e-26 89.6 0.2 2e-12 47.0 0.0 6.4 6 1 0 6 6 6 4 Cyclic nucleotide-binding domain Patatin PF01734.22 CCD24791.1 - 3e-17 63.5 3.9 5.6e-16 59.3 2.6 3.0 2 1 0 2 2 2 1 Patatin-like phospholipase OGG_N PF07934.12 CCD24792.1 - 2.3e-20 72.9 0.3 4.6e-20 71.9 0.3 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CCD24792.1 - 2.6e-20 72.9 0.0 4.3e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Elf4 PF07011.11 CCD24792.1 - 0.069 13.1 1.5 11 6.1 0.0 2.8 3 0 0 3 3 3 0 Early Flowering 4 domain PIF1 PF05970.14 CCD24793.1 - 1.1e-74 251.8 1.2 5.4e-57 193.6 0.2 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CCD24793.1 - 9.7e-19 67.8 0.0 1.5e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCD24793.1 - 1.7e-09 38.2 0.0 3.6e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCD24793.1 - 0.00078 19.7 0.1 0.006 16.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 CCD24793.1 - 0.0046 15.0 0.1 0.036 12.0 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA_7 PF12775.7 CCD24793.1 - 0.0058 16.2 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region UvrD_C_2 PF13538.6 CCD24793.1 - 0.0071 16.2 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain SH3_13 PF18335.1 CCD24793.1 - 0.034 14.0 0.0 0.097 12.5 0.0 1.7 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Helicase_RecD PF05127.14 CCD24793.1 - 0.069 13.0 0.3 0.33 10.8 0.3 2.1 1 1 0 1 1 1 0 Helicase FtsK_SpoIIIE PF01580.18 CCD24793.1 - 0.087 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 CCD24793.1 - 0.093 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.9 CCD24793.1 - 0.11 11.7 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CCD24793.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RRM_1 PF00076.22 CCD24794.1 - 4.9e-32 109.6 1.6 5.5e-15 54.9 0.0 3.8 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CCD24794.1 - 3.4e-08 33.4 0.0 0.0006 19.8 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CCD24794.1 - 0.0016 18.2 0.0 2.1 8.3 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 CCD24794.1 - 0.0063 16.5 0.2 3.6 7.7 0.2 2.9 2 0 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 CCD24794.1 - 0.047 13.8 0.1 2.5 8.3 0.0 3.4 3 1 0 3 3 3 0 RNA recognition motif PHM7_cyt PF14703.6 CCD24794.1 - 4 7.6 9.0 18 5.5 0.2 3.9 2 2 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter AAA_2 PF07724.14 CCD24795.1 - 5.1e-47 160.2 0.0 1.4e-45 155.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CCD24795.1 - 4.3e-28 97.3 6.9 1.1e-27 95.9 0.9 3.1 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 CCD24795.1 - 9e-23 81.2 0.1 1.8e-13 51.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CCD24795.1 - 2.8e-22 78.6 0.5 9.7e-22 76.8 0.5 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CCD24795.1 - 4.5e-15 55.8 0.1 4.1e-07 30.1 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 CCD24795.1 - 2.2e-13 50.1 4.9 1.4e-07 31.5 0.3 4.1 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 CCD24795.1 - 2.3e-12 46.9 0.2 6.5e-08 32.5 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 CCD24795.1 - 1.1e-08 35.6 4.3 0.00011 22.7 0.0 4.1 4 1 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 CCD24795.1 - 3.9e-06 27.2 0.3 0.1 12.8 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CCD24795.1 - 2e-05 24.6 0.0 0.039 14.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CCD24795.1 - 0.0002 20.9 0.0 0.035 13.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 CCD24795.1 - 0.00033 20.1 0.0 1.2 8.5 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CCD24795.1 - 0.0012 18.6 0.0 0.13 11.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain Torsin PF06309.11 CCD24795.1 - 0.0016 18.6 0.0 0.0069 16.5 0.0 2.1 1 0 0 1 1 1 1 Torsin IstB_IS21 PF01695.17 CCD24795.1 - 0.002 17.9 0.0 0.21 11.3 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 CCD24795.1 - 0.0021 17.4 0.4 0.44 9.8 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin ATPase_2 PF01637.18 CCD24795.1 - 0.0023 17.9 7.0 3.9 7.3 0.1 4.8 3 2 0 4 4 4 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 CCD24795.1 - 0.0039 17.4 0.0 0.78 9.9 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.13 CCD24795.1 - 0.0041 16.3 0.0 0.17 11.0 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.12 CCD24795.1 - 0.0052 16.7 0.0 4.3 7.2 0.0 2.8 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 CCD24795.1 - 0.014 15.9 3.2 1.9 9.0 0.0 3.7 3 0 0 3 3 3 0 ABC transporter AAA_29 PF13555.6 CCD24795.1 - 0.02 14.6 0.1 3.8 7.3 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCD24795.1 - 0.022 14.7 0.0 3.1 7.7 0.0 2.9 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 CCD24795.1 - 0.03 14.5 0.0 8.7 6.6 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_3 PF07726.11 CCD24795.1 - 0.047 13.6 0.0 1.1 9.2 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PEPCK_ATP PF01293.20 CCD24795.1 - 0.047 12.4 0.0 0.081 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase RNA_helicase PF00910.22 CCD24795.1 - 0.048 14.0 0.1 7.9 6.9 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Viral_helicase1 PF01443.18 CCD24795.1 - 0.065 13.0 0.0 14 5.3 0.0 2.7 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 CCD24795.1 - 0.1 12.6 0.0 7.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Spc7 PF08317.11 CCD24795.1 - 0.52 9.1 16.2 0.94 8.3 16.2 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_18 PF13238.6 CCD24795.1 - 0.86 10.1 7.0 8.1 7.0 0.0 3.8 5 0 0 5 5 2 0 AAA domain BLOC1_2 PF10046.9 CCD24795.1 - 3.3 8.1 8.7 7.2 7.0 2.3 3.7 4 0 0 4 4 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fe-S_biosyn PF01521.20 CCD24796.1 - 4.8e-18 65.4 0.0 3.8e-17 62.5 0.0 2.3 2 1 0 2 2 2 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.7 CCD24796.1 - 0.043 14.0 1.7 0.48 10.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3853) MFS_1 PF07690.16 CCD24797.1 - 3.2e-39 134.8 31.7 3.2e-39 134.8 31.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCD24797.1 - 1.7e-09 37.0 27.4 1.9e-09 36.9 24.3 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 CCD24797.1 - 4.7e-09 35.2 5.1 8.6e-09 34.4 5.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M1 PF01433.20 CCD24798.1 - 7.4e-08 32.2 0.2 2.8e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CCD24798.1 - 2.2e-07 31.2 2.6 0.011 15.9 0.7 3.0 1 1 1 2 2 2 2 Peptidase M1 N-terminal domain BUD22 PF09073.10 CCD24798.1 - 0.13 11.5 15.8 0.23 10.8 15.8 1.3 1 0 0 1 1 1 0 BUD22 CDC27 PF09507.10 CCD24798.1 - 0.36 10.2 12.9 0.67 9.3 12.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 CCD24798.1 - 1.3 7.2 11.2 2.5 6.3 11.2 1.5 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 CCD24798.1 - 8.1 6.3 14.3 22 4.9 14.3 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Creatinase_N_2 PF16189.5 CCD24799.1 - 2.8e-40 138.0 0.3 2.8e-40 138.0 0.3 2.7 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CCD24799.1 - 1.3e-37 129.5 0.0 1.9e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 CCD24799.1 - 2.9e-21 75.3 0.7 2.9e-21 75.3 0.7 2.4 3 0 0 3 3 3 1 C-terminal region of peptidase_M24 TDH PF03347.13 CCD24799.1 - 0.22 11.1 1.2 0.81 9.2 0.1 2.4 3 0 0 3 3 3 0 Vibrio thermostable direct hemolysin KH_1 PF00013.29 CCD24800.1 - 4.4e-05 23.2 0.0 0.2 11.5 0.0 3.8 3 0 0 3 3 3 2 KH domain AAA PF00004.29 CCD24802.1 - 2.1e-93 309.7 0.0 8.5e-47 158.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCD24802.1 - 7.3e-22 76.9 0.1 6.1e-10 38.8 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CCD24802.1 - 1.3e-14 54.2 0.0 2.4e-07 30.6 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCD24802.1 - 1.9e-13 51.2 0.8 7.4e-05 23.2 0.0 4.1 3 2 0 3 3 2 2 AAA ATPase domain AAA_2 PF07724.14 CCD24802.1 - 1.2e-10 41.8 0.0 0.00095 19.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CCD24802.1 - 2.2e-10 41.0 0.9 0.02 15.2 0.0 5.0 2 2 1 3 3 3 2 AAA domain AAA_33 PF13671.6 CCD24802.1 - 2.7e-10 40.6 0.0 0.00015 21.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 CCD24802.1 - 1.5e-09 38.0 0.3 0.001 19.1 0.1 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 CCD24802.1 - 3.4e-09 36.6 0.9 7.4e-05 22.7 0.1 3.5 3 0 0 3 3 3 2 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 CCD24802.1 - 7.9e-09 35.2 0.0 0.00033 20.0 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 CCD24802.1 - 1.3e-07 31.8 0.0 0.024 14.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CCD24802.1 - 1.6e-07 32.0 2.5 0.0016 19.0 0.0 3.6 4 0 0 4 4 2 2 AAA domain RNA_helicase PF00910.22 CCD24802.1 - 3.3e-07 30.7 0.0 0.03 14.7 0.0 3.0 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.12 CCD24802.1 - 1.6e-06 27.6 0.0 0.047 13.0 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.17 CCD24802.1 - 3.1e-06 27.1 0.1 0.048 13.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 CCD24802.1 - 3.9e-06 26.4 0.3 0.053 12.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 CCD24802.1 - 5.8e-06 26.4 0.0 0.025 14.5 0.0 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_28 PF13521.6 CCD24802.1 - 5.9e-06 26.6 0.0 0.066 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 CCD24802.1 - 7e-06 26.6 7.3 0.014 15.9 0.0 4.0 4 1 0 4 4 2 2 ABC transporter AAA_3 PF07726.11 CCD24802.1 - 7e-06 25.9 0.0 0.053 13.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 CCD24802.1 - 1.9e-05 24.9 0.0 0.0012 19.0 0.0 2.8 2 0 0 2 2 2 1 Cytidylate kinase-like family NACHT PF05729.12 CCD24802.1 - 7.3e-05 22.7 0.1 0.51 10.2 0.0 3.1 3 0 0 3 3 2 2 NACHT domain AAA_17 PF13207.6 CCD24802.1 - 9.4e-05 22.9 2.3 0.13 12.7 0.1 3.8 3 1 0 3 3 2 1 AAA domain TsaE PF02367.17 CCD24802.1 - 0.00011 22.2 0.0 0.73 9.9 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CCD24802.1 - 0.0002 20.9 0.0 0.45 10.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Viral_helicase1 PF01443.18 CCD24802.1 - 0.00026 20.8 0.3 1.1 8.9 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase SKI PF01202.22 CCD24802.1 - 0.00026 21.1 0.8 0.2 11.7 0.0 3.0 3 0 0 3 3 2 1 Shikimate kinase AAA_25 PF13481.6 CCD24802.1 - 0.00027 20.6 0.4 1.8 8.1 0.0 3.8 3 1 0 4 4 4 1 AAA domain DUF815 PF05673.13 CCD24802.1 - 0.00031 20.0 0.0 0.15 11.2 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 CCD24802.1 - 0.00038 20.2 0.0 0.29 10.8 0.0 2.8 2 1 1 3 3 3 1 Sigma-54 interaction domain AAA_24 PF13479.6 CCD24802.1 - 0.00048 19.9 0.4 0.91 9.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain NB-ARC PF00931.22 CCD24802.1 - 0.00094 18.4 0.0 1.1 8.4 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain CPT PF07931.12 CCD24802.1 - 0.0013 18.6 0.0 0.031 14.1 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 CCD24802.1 - 0.0014 18.0 0.0 1.7 7.9 0.0 3.3 2 1 0 3 3 3 1 KaiC Sigma54_activ_2 PF14532.6 CCD24802.1 - 0.0014 18.7 0.0 2.9 8.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 CCD24802.1 - 0.0026 17.7 0.0 2.2 8.1 0.0 3.3 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 CCD24802.1 - 0.004 16.3 2.2 2 7.4 0.0 2.9 3 1 0 3 3 2 2 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 CCD24802.1 - 0.018 15.4 0.1 5.3 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 CCD24802.1 - 0.018 14.8 0.0 8.2 6.2 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 CCD24802.1 - 0.023 14.2 0.1 3 7.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.15 CCD24802.1 - 0.043 13.7 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 NTPase Cytidylate_kin PF02224.18 CCD24802.1 - 0.049 13.4 4.5 1.1 9.0 0.0 3.8 4 0 0 4 4 4 0 Cytidylate kinase NifW PF03206.14 CCD24802.1 - 0.13 12.8 0.0 0.51 10.9 0.0 2.0 1 0 0 1 1 1 0 Nitrogen fixation protein NifW MMR_HSR1 PF01926.23 CCD24802.1 - 0.21 11.7 1.9 2.8 8.0 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase Hydin_ADK PF17213.3 CCD24802.1 - 0.27 11.5 10.2 0.76 10.0 0.0 3.9 5 0 0 5 5 4 0 Hydin Adenylate kinase-like domain AAA_11 PF13086.6 CCD24802.1 - 0.42 10.3 0.0 0.62 9.8 0.0 4.3 3 1 0 4 4 3 0 AAA domain CLP1_P PF16575.5 CCD24803.1 - 4.7e-27 95.0 0.5 2.7e-26 92.5 0.5 2.1 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 CCD24803.1 - 0.00096 19.2 0.1 0.0025 17.9 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 CCD24803.1 - 0.005 16.2 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.20 CCD24803.1 - 0.0066 15.7 3.7 0.013 14.7 3.7 1.6 1 0 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.27 CCD24803.1 - 0.014 15.9 0.1 0.096 13.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 CCD24803.1 - 0.05 13.6 0.0 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain WSC PF01822.19 CCD24804.1 - 4.4e-08 33.2 15.1 4.4e-08 33.2 15.1 2.9 3 0 0 3 3 3 1 WSC domain Orf78 PF06024.12 CCD24804.1 - 0.0012 19.1 0.3 0.0012 19.1 0.3 3.5 4 0 0 4 4 4 1 Orf78 (ac78) RCR PF12273.8 CCD24804.1 - 0.0014 19.3 0.4 0.0067 17.1 0.0 2.3 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.6 CCD24804.1 - 0.005 16.8 1.0 0.005 16.8 1.0 4.7 2 1 0 3 3 3 1 TMEM154 protein family YajC PF02699.15 CCD24804.1 - 0.0069 16.2 0.6 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 Preprotein translocase subunit TMEM132D_C PF15706.5 CCD24804.1 - 0.038 13.8 0.2 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term SKG6 PF08693.10 CCD24804.1 - 1.7 8.1 7.1 9.9 5.7 7.1 2.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Prp19 PF08606.11 CCD24805.1 - 3.6e-30 103.7 2.0 5.5e-30 103.2 2.0 1.3 1 0 0 1 1 1 1 Prp19/Pso4-like BRE1 PF08647.11 CCD24805.1 - 7.1e-05 22.8 6.2 0.00012 22.1 6.2 1.3 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase U-box PF04564.15 CCD24805.1 - 0.00018 21.6 0.2 0.00052 20.1 0.1 1.8 1 1 0 1 1 1 1 U-box domain zf-Nse PF11789.8 CCD24805.1 - 0.0091 15.8 0.7 0.14 12.0 0.0 2.4 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Uso1_p115_C PF04871.13 CCD24805.1 - 0.072 13.5 6.5 0.12 12.8 6.5 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HALZ PF02183.18 CCD24805.1 - 0.15 12.3 3.9 0.67 10.2 0.2 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 CCD24805.1 - 0.19 11.9 3.5 0.25 11.5 0.2 2.2 1 1 0 2 2 2 0 bZIP transcription factor GIT_CC PF16559.5 CCD24805.1 - 1.3 8.9 7.3 0.52 10.2 1.2 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 CCD24805.1 - 1.6 9.4 6.5 3.4 8.4 5.2 1.9 1 1 1 2 2 2 0 Initiation control protein YabA ubiquitin PF00240.23 CCD24806.1 - 5.4e-102 333.6 13.3 1.9e-33 114.0 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 CCD24806.1 - 1.3e-48 162.7 13.8 1.2e-15 57.1 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CCD24806.1 - 7.6e-18 64.8 6.1 0.00026 21.4 0.1 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 CCD24806.1 - 1.7e-12 47.1 1.7 0.016 15.1 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CCD24806.1 - 1.8e-12 47.5 2.2 0.013 15.8 0.1 3.1 1 1 2 3 3 3 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CCD24806.1 - 4.7e-11 42.8 1.3 0.073 13.2 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CCD24806.1 - 7.2e-10 39.4 0.3 0.21 12.1 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CCD24806.1 - 2.4e-08 34.0 0.2 0.39 10.5 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 CCD24806.1 - 2.4e-06 27.5 16.0 11 6.1 0.2 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF3861 PF12977.7 CCD24806.1 - 8.5e-05 22.7 1.0 8 6.7 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 CCD24806.1 - 0.00015 21.5 2.1 6.9 6.6 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF2870 PF11069.8 CCD24806.1 - 0.00028 21.2 0.0 20 5.6 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 CCD24806.1 - 0.00061 19.2 0.1 1.1 8.5 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase Big_7 PF17957.1 CCD24806.1 - 0.0011 19.6 0.1 34 5.3 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig domain YcgR_2 PF12945.7 CCD24806.1 - 0.003 17.7 2.9 19 5.5 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein YcgR UDP-g_GGTase PF06427.11 CCD24806.1 - 0.0069 16.5 3.0 4.5 7.4 0.0 3.1 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 CCD24806.1 - 0.0077 15.7 0.0 15 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) DUF493 PF04359.14 CCD24806.1 - 0.031 14.9 0.0 95 3.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 CCD24806.1 - 0.031 14.0 0.0 71 3.2 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 CCD24806.1 - 0.032 14.8 0.3 96 3.7 0.0 3.3 3 0 0 3 3 3 0 ACT domain ORF11CD3 PF10549.9 CCD24806.1 - 0.083 13.0 0.0 62 3.8 0.0 3.4 3 0 0 3 3 3 0 ORF11CD3 domain ProRS-C_2 PF09181.10 CCD24806.1 - 0.12 12.5 2.6 72 3.6 0.1 3.2 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 CCD24806.1 - 0.13 12.4 18.4 4.5 7.6 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif Myosin_N PF02736.19 CCD24806.1 - 0.27 11.1 3.4 76 3.3 0.0 4.3 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DMA PF03474.14 CCD24806.1 - 0.46 10.1 1.7 1.1e+02 2.5 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif Plexin_cytopl PF08337.12 CCD24806.1 - 0.53 8.9 10.5 8.3 4.9 0.4 3.9 2 1 1 4 4 4 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.16 CCD24806.1 - 0.85 9.4 5.0 67 3.3 0.1 3.3 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain FlgD_ig PF13860.6 CCD24806.1 - 2.8 7.9 4.9 1.2e+02 2.6 0.1 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain SHR-BD PF06650.12 CCD24807.1 - 2.5e-90 302.6 10.2 7.1e-86 287.9 1.1 3.5 3 0 0 3 3 3 3 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 CCD24807.1 - 6.2e-73 245.1 1.2 6.2e-73 245.1 1.2 6.0 5 1 1 6 6 6 2 Repeating coiled region of VPS13 VPS13_C PF16909.5 CCD24807.1 - 9.3e-69 230.8 12.6 8.6e-67 224.3 0.7 3.6 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 CCD24807.1 - 3.6e-68 229.9 13.0 5.7e-67 226.0 3.5 3.7 3 1 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 CCD24807.1 - 3e-35 120.8 0.2 1.2e-34 118.9 0.2 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 CCD24807.1 - 0.17 12.3 0.1 0.85 10.0 0.0 2.2 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain Fer2_3 PF13085.6 CCD24808.1 - 1.1e-32 112.3 0.1 1.7e-32 111.6 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CCD24808.1 - 6e-08 33.1 5.1 6e-08 33.1 5.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CCD24808.1 - 7.2e-07 29.6 3.8 7.2e-07 29.6 3.8 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CCD24808.1 - 9.8e-07 28.8 2.8 9.8e-07 28.8 2.8 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 CCD24808.1 - 0.00036 21.1 2.6 0.00036 21.1 2.6 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CCD24808.1 - 0.0051 16.7 1.5 0.0051 16.7 1.5 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 CCD24808.1 - 9.9 6.4 16.9 0.46 10.7 8.4 2.8 2 1 0 2 2 2 0 4Fe-4S dicluster domain Autophagy_act_C PF03987.15 CCD24809.1 - 3.4e-11 43.5 0.9 8.4e-11 42.3 0.3 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Elong-fact-P_C PF09285.11 CCD24809.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Elongation factor P, C-terminal MIP PF00230.20 CCD24810.1 - 2.3e-75 253.2 8.3 3.2e-75 252.7 8.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein Ribosomal_L7Ae PF01248.26 CCD24811.1 - 3.6e-23 81.1 0.3 5.7e-23 80.5 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CCD24811.1 - 0.00026 21.1 0.1 0.00042 20.4 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 VasI PF11319.8 CCD24812.1 - 0.0044 16.7 0.3 0.0062 16.2 0.3 1.2 1 0 0 1 1 1 1 Type VI secretion system VasI, EvfG, VC_A0118 FAM198 PF15051.6 CCD24812.1 - 0.11 11.3 0.1 0.18 10.7 0.1 1.3 1 0 0 1 1 1 0 FAM198 protein HSBP1 PF06825.12 CCD24812.1 - 0.19 11.6 13.3 0.52 10.2 0.5 3.2 3 1 0 3 3 3 0 Heat shock factor binding protein 1 Ferric_reduct PF01794.19 CCD24813.1 - 2.9e-26 92.0 13.8 2.9e-26 92.0 13.8 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CCD24813.1 - 6.2e-20 71.3 0.0 1.1e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 CCD24813.1 - 1.1e-19 71.1 0.0 2.2e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain MLANA PF14991.6 CCD24813.1 - 0.0067 16.7 2.5 1.8 8.9 0.0 3.4 3 0 0 3 3 3 1 Protein melan-A Sugar_tr PF00083.24 CCD24814.1 - 5.4e-162 539.7 34.3 6.2e-162 539.6 34.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD24814.1 - 2e-28 99.4 38.5 4.6e-26 91.6 25.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 CCD24814.1 - 0.00063 18.3 1.1 0.00063 18.3 1.1 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector DUF2530 PF10745.9 CCD24814.1 - 7.2 6.9 7.4 0.51 10.6 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Sugar_tr PF00083.24 CCD24815.1 - 2.5e-163 544.2 34.0 2.9e-163 543.9 34.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD24815.1 - 2.7e-29 102.2 37.7 1.7e-26 93.0 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCD24815.1 - 0.0022 16.5 1.2 0.0022 16.5 1.2 1.9 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 CCD24815.1 - 0.0031 16.0 4.0 0.0031 16.0 4.0 2.0 2 1 0 2 2 2 1 Transmembrane secretion effector Glyco_hydro_92 PF07971.12 CCD24815.1 - 0.21 10.5 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 SCP_3 PF17844.1 CCD24816.1 - 0.15 11.9 0.1 1.9 8.3 0.0 2.2 1 1 1 2 2 2 0 Bacterial SCP ortholog PRP21_like_P PF12230.8 CCD24817.1 - 1e-35 123.6 7.8 1.5e-33 116.5 7.8 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 CCD24817.1 - 0.021 14.8 1.1 0.033 14.2 0.1 1.9 2 0 0 2 2 2 0 Surp module DUF5045 PF16464.5 CCD24817.1 - 0.06 13.7 0.2 1.4 9.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5045) Sugar_tr PF00083.24 CCD24818.1 - 1.4e-64 218.7 26.6 1.5e-64 218.5 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD24818.1 - 0.0018 17.3 21.0 0.004 16.1 21.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily GSHPx PF00255.19 CCD24819.1 - 2.9e-45 152.3 0.3 3.7e-45 151.9 0.3 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CCD24819.1 - 3e-05 23.9 0.1 6.6e-05 22.8 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CCD24819.1 - 0.00049 19.8 0.1 0.00081 19.1 0.1 1.5 1 1 0 1 1 1 1 Redoxin Sir1 PF11603.8 CCD24820.1 - 6.2e-60 201.0 10.8 7e-31 107.2 1.9 3.7 3 0 0 3 3 3 3 Regulatory protein Sir1 ADH_N_2 PF16884.5 CCD24821.1 - 1.4e-22 79.6 0.0 2.7e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 CCD24821.1 - 1.5e-16 60.5 0.1 2.8e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCD24821.1 - 0.00039 21.5 0.0 0.00094 20.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 CCD24821.1 - 0.0062 16.3 0.1 0.0085 15.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) LAB_N PF07578.11 CCD24821.1 - 0.04 14.0 0.1 0.083 13.0 0.1 1.5 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain Epimerase PF01370.21 CCD24822.1 - 4.1e-16 59.2 0.0 6e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCD24822.1 - 3.6e-14 52.5 0.0 4.9e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CCD24822.1 - 1.3e-07 31.1 0.0 0.0017 17.6 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 CCD24822.1 - 7.5e-06 25.9 0.1 2e-05 24.6 0.0 1.9 2 1 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CCD24822.1 - 4.4e-05 23.0 0.0 0.00012 21.7 0.1 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase OMS28_porin PF03532.13 CCD24822.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.5 1 0 0 1 1 1 1 OMS28 porin DapB_N PF01113.20 CCD24822.1 - 0.0026 17.9 0.0 0.0053 16.9 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 CCD24822.1 - 0.0042 16.7 0.0 0.046 13.3 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 CCD24822.1 - 0.0053 16.2 0.1 0.013 15.0 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 CCD24822.1 - 0.012 14.8 0.1 0.018 14.2 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 CCD24822.1 - 0.068 13.8 0.0 0.22 12.1 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 CCD24822.1 - 0.077 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain MFS_1 PF07690.16 CCD24823.1 - 0.002 17.1 0.1 0.002 17.1 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ECF-ribofla_trS PF07155.12 CCD24823.1 - 0.068 13.2 2.5 0.078 13.0 2.5 1.0 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component DEAD PF00270.29 CCD24825.1 - 1.4e-08 34.7 0.0 3.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CCD24825.1 - 0.008 16.2 0.0 0.026 14.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCD24825.1 - 0.14 12.5 0.0 0.45 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain Sir1 PF11603.8 CCD24826.1 - 3.4e-25 88.9 0.0 4.8e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Regulatory protein Sir1 Reg_prop PF07494.11 CCD24826.1 - 0.048 13.9 0.1 0.21 11.9 0.1 2.1 2 0 0 2 2 2 0 Two component regulator propeller EABR PF12180.8 CCD24826.1 - 0.83 9.3 3.3 0.61 9.8 1.0 1.9 2 0 0 2 2 2 0 TSG101 and ALIX binding domain of CEP55 Sir1 PF11603.8 CCD24827.1 - 0.12 12.9 2.5 0.12 12.9 0.3 2.2 2 1 0 2 2 2 0 Regulatory protein Sir1 Ribonuclease_3 PF00636.26 CCD24828.1 - 5.3e-21 75.2 2.0 2.7e-20 73.0 0.0 3.0 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CCD24828.1 - 1.3e-16 60.9 0.0 2.6e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 CCD24828.1 - 2.1e-14 53.9 0.1 2.7e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif Lipase_GDSL_3 PF14606.6 CCD24828.1 - 0.37 10.9 5.4 2.8 8.0 0.9 2.6 2 1 1 3 3 3 0 GDSL-like Lipase/Acylhydrolase family GFO_IDH_MocA PF01408.22 CCD24829.1 - 1.7e-20 74.0 0.1 4.6e-20 72.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CCD24829.1 - 2.9e-08 33.7 0.0 5.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain BRCA-2_OB3 PF09104.10 CCD24829.1 - 0.077 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 TFIID-18kDa PF02269.16 CCD24830.1 - 3.3e-32 110.4 0.0 5.6e-32 109.6 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID-31kDa PF02291.15 CCD24830.1 - 0.027 14.5 0.1 0.037 14.1 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 CCD24830.1 - 0.027 14.8 6.0 0.037 14.4 0.0 2.8 3 1 0 3 3 3 0 Core histone H2A/H2B/H3/H4 PBP1_TM PF14812.6 CCD24830.1 - 2 8.8 10.4 0.39 11.1 6.7 1.8 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ERO1 PF04137.15 CCD24831.1 - 2e-117 392.3 5.5 2e-117 392.3 5.5 2.2 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Proteasome PF00227.26 CCD24832.1 - 6.4e-58 195.4 0.0 8.1e-58 195.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCD24832.1 - 1.4e-09 37.5 0.2 4.7e-09 35.8 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature COX14 PF14880.6 CCD24833.1 - 2.3e-22 78.6 1.8 2.5e-22 78.4 1.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Ish1 PF10281.9 CCD24834.1 - 1.5e-45 153.1 37.8 8.4e-11 42.0 0.0 6.8 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein SAP PF02037.27 CCD24834.1 - 0.11 12.3 0.1 1.9 8.3 0.0 3.2 3 0 0 3 3 3 0 SAP domain SAM_2 PF07647.17 CCD24834.1 - 0.17 12.0 9.2 5.9 7.1 0.2 4.8 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) DUF4286 PF14114.6 CCD24834.1 - 0.18 12.3 4.6 42 4.7 0.0 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4286) GP52 PF17468.2 CCD24834.1 - 0.29 11.3 11.9 0.54 10.4 0.1 4.5 5 0 0 5 5 5 0 Phage gene product 52 YtxH PF12732.7 CCD24834.1 - 1.6 9.3 18.8 17 6.0 0.3 6.0 5 1 1 6 6 6 0 YtxH-like protein SAM_1 PF00536.30 CCD24834.1 - 2.4 8.7 7.2 14 6.2 0.1 3.9 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) Peptidase_M4 PF01447.18 CCD24835.1 - 0.0026 18.3 0.5 0.084 13.4 0.0 2.3 2 0 0 2 2 2 1 Thermolysin metallopeptidase, catalytic domain FAD_binding_6 PF00970.24 CCD24836.1 - 2.4e-29 101.6 0.0 4.4e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CCD24836.1 - 2.8e-27 95.5 0.0 4.2e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CCD24836.1 - 1.6e-05 25.0 0.0 0.00021 21.4 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DUF1656 PF07869.12 CCD24836.1 - 7.6 6.6 7.7 0.82 9.7 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) Sugar_tr PF00083.24 CCD24837.1 - 9.6e-44 150.0 17.9 3.2e-42 145.0 17.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD24837.1 - 3.5e-23 82.1 14.9 8.5e-15 54.5 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1206 PF06724.11 CCD24837.1 - 0.017 15.2 2.5 7.1 6.8 0.8 3.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) DUF3341 PF11821.8 CCD24837.1 - 0.12 12.0 0.7 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) FAM178 PF14816.6 CCD24837.1 - 0.22 10.4 0.0 0.43 9.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function, FAM178 Gtr1_RagA PF04670.12 CCD24838.1 - 1.9e-94 315.3 4.9 2.4e-94 315.1 4.9 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 CCD24838.1 - 2e-09 37.3 0.7 5.1e-09 35.9 0.2 1.9 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CCD24838.1 - 9.6e-09 35.5 0.0 2.8e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CCD24838.1 - 1.3e-07 31.7 0.0 2.8e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 CCD24838.1 - 1.3e-07 31.2 0.2 2.2e-07 30.5 0.2 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CCD24838.1 - 0.025 14.5 1.0 0.74 9.7 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase MEA1 PF06910.11 CCD24838.1 - 0.027 15.1 0.1 0.055 14.1 0.1 1.5 1 0 0 1 1 1 0 Male enhanced antigen 1 (MEA1) Guanylate_kin PF00625.21 CCD24838.1 - 0.17 11.5 3.2 0.15 11.8 0.4 2.2 2 1 0 2 2 2 0 Guanylate kinase Secretin_N_2 PF07655.13 CCD24838.1 - 1.6 9.4 20.1 0.62 10.6 8.8 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain ABC_tran PF00005.27 CCD24838.1 - 3.2 8.3 8.8 8.3 6.9 8.8 2.1 1 1 0 1 1 1 0 ABC transporter Pyr_redox_2 PF07992.14 CCD24839.1 - 7.1e-49 166.6 0.0 1e-48 166.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCD24839.1 - 7.4e-13 48.9 0.1 5.7e-11 42.8 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCD24839.1 - 0.0057 16.0 7.1 0.47 9.7 0.1 3.7 4 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase RtcR PF06956.11 CCD24840.1 - 3.9 6.8 8.0 0.41 10.0 1.7 2.3 2 0 0 2 2 2 0 Regulator of RNA terminal phosphate cyclase Ribosomal_L30 PF00327.20 CCD24841.1 - 7.9e-12 44.9 0.5 1.4e-11 44.1 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Exo_endo_phos PF03372.23 CCD24842.1 - 1.5e-16 60.7 0.0 2.2e-16 60.1 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRIF1 PF15741.5 CCD24842.1 - 2.7 6.4 9.6 0.9 8.0 1.1 2.1 2 0 0 2 2 2 0 Ligand-dependent nuclear receptor-interacting factor 1 Nab6_mRNP_bdg PF10567.9 CCD24843.1 - 5.7e-86 288.9 47.2 3.6e-65 220.5 18.7 4.0 4 0 0 4 4 4 2 RNA-recognition motif RRM PF10378.9 CCD24843.1 - 6.1e-18 64.3 9.4 2.8e-17 62.2 9.4 2.2 1 0 0 1 1 1 1 Putative RRM domain RRM_1 PF00076.22 CCD24843.1 - 1.4e-05 24.9 0.1 0.012 15.4 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 CCD24844.1 - 8.1e-35 120.4 56.3 7.8e-33 113.8 56.3 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCD24844.1 - 0.00011 21.3 9.3 0.00011 21.3 9.3 4.0 1 1 2 3 3 3 1 Sugar (and other) transporter Ost5 PF05251.12 CCD24844.1 - 0.0094 16.2 2.0 0.0094 16.2 2.0 4.6 4 2 2 6 6 6 1 Oligosaccharyltransferase subunit 5 Anp1 PF03452.14 CCD24845.1 - 1.5e-119 398.2 0.0 2.3e-119 397.7 0.0 1.3 1 0 0 1 1 1 1 Anp1 Comm PF15957.5 CCD24845.1 - 0.048 14.0 0.0 0.25 11.7 0.0 2.1 2 0 0 2 2 2 0 Commissureless DUF2232 PF09991.9 CCD24845.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) TAF8_C PF10406.9 CCD24846.1 - 1.9e-18 66.8 0.1 1.9e-18 66.8 0.1 3.5 3 1 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term CTK3_C PF12350.8 CCD24848.1 - 3e-15 56.1 2.5 8.4e-15 54.7 2.5 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.8 CCD24848.1 - 3.2e-05 23.9 4.5 0.03 14.3 0.1 3.0 3 0 0 3 3 3 2 CTD kinase subunit gamma CTK3 Fzo_mitofusin PF04799.13 CCD24848.1 - 0.027 14.0 1.0 0.072 12.6 1.0 1.7 1 0 0 1 1 1 0 fzo-like conserved region Bul1_N PF04425.12 CCD24849.1 - 9e-169 562.0 14.3 9e-169 562.0 14.3 3.1 3 0 0 3 3 3 1 Bul1 N terminus Bul1_C PF04426.12 CCD24849.1 - 4e-82 275.7 12.5 9.2e-58 195.8 4.5 5.0 4 1 1 5 5 5 2 Bul1 C terminus Ubie_methyltran PF01209.18 CCD24850.1 - 3.2e-97 324.5 0.1 3.8e-97 324.2 0.1 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CCD24850.1 - 9.6e-12 45.5 0.0 2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCD24850.1 - 5.3e-10 39.8 0.0 1e-09 38.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCD24850.1 - 3.7e-08 33.3 0.0 6e-08 32.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCD24850.1 - 6.4e-08 33.2 0.0 1.1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCD24850.1 - 4.8e-07 29.8 0.0 7.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CCD24850.1 - 0.014 15.2 0.0 0.25 11.2 0.0 2.4 2 1 0 3 3 3 0 Hypothetical methyltransferase Zds_C PF08632.10 CCD24851.1 - 6.4e-28 96.3 1.2 1.1e-27 95.4 1.2 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2824 PF11039.8 CCD24851.1 - 2.8 7.9 5.0 0.84 9.6 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2824) DUF1892 PF08987.10 CCD24852.1 - 3.6e-51 172.0 9.9 9.6e-51 170.6 9.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1892) SpoU_methylase PF00588.19 CCD24852.1 - 0.045 13.9 0.0 0.059 13.5 0.0 1.1 1 0 0 1 1 1 0 SpoU rRNA Methylase family Pribosyltran PF00156.27 CCD24853.1 - 4.7e-16 58.7 0.1 7.7e-16 58.0 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SRP19 PF01922.17 CCD24854.1 - 3.9e-30 104.6 0.0 7.4e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein PXA PF02194.15 CCD24855.1 - 6.8e-35 120.7 2.0 6.8e-35 120.7 2.0 3.2 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 CCD24855.1 - 2.5e-23 82.8 0.0 9.7e-23 80.9 0.0 2.1 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 CCD24855.1 - 3.6e-11 43.0 3.6 3.6e-11 43.0 3.6 2.9 2 0 0 2 2 2 1 PX domain Nup188 PF10487.9 CCD24856.1 - 8.1e-198 659.5 80.7 8.1e-198 659.5 80.7 3.2 3 1 0 3 3 3 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 CCD24856.1 - 7.5e-17 61.2 0.7 2.6e-16 59.4 0.7 1.9 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain WD40 PF00400.32 CCD24857.1 - 1.5e-19 70.0 9.0 0.00039 21.2 0.0 6.3 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD24857.1 - 1e-13 51.4 0.2 0.003 17.8 0.0 5.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCD24857.1 - 9.4e-07 28.1 0.2 0.48 9.3 0.1 3.3 3 0 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CCD24857.1 - 0.00018 21.5 3.1 0.13 12.2 0.2 3.9 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 CCD24857.1 - 0.12 12.5 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region CUE PF02845.16 CCD24858.1 - 3.5e-11 42.6 0.0 6.2e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 CUE domain Sigma_reg_N PF13800.6 CCD24858.1 - 0.1 12.9 1.1 0.17 12.2 0.3 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF4969 PF16339.5 CCD24858.1 - 0.11 12.9 0.2 0.11 12.9 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) TFIIA PF03153.13 CCD24858.1 - 0.17 11.8 19.2 0.21 11.5 19.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 CCD24858.1 - 5.3 8.1 9.7 1.1 10.2 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Glyco_transf_20 PF00982.21 CCD24859.1 - 1.1e-165 551.9 1.8 1.1e-165 551.9 1.8 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CCD24859.1 - 6.3e-43 146.6 0.1 2.2e-42 144.8 0.0 1.9 2 0 0 2 2 2 1 Trehalose-phosphatase SUIM_assoc PF16619.5 CCD24859.1 - 0.43 10.7 6.4 0.87 9.7 0.2 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 zf-C3HC4 PF00097.25 CCD24860.1 - 1.5e-09 37.6 7.5 1.5e-09 37.6 7.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CCD24860.1 - 4.6e-09 36.0 13.0 6.7e-09 35.5 4.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCD24860.1 - 7.6e-09 35.6 8.8 7.6e-09 35.6 8.8 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CCD24860.1 - 9.1e-08 32.3 7.6 9.1e-08 32.3 7.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CCD24860.1 - 1.6e-07 31.0 8.4 1.6e-07 31.0 8.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCD24860.1 - 3e-07 30.4 7.2 3e-07 30.4 7.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CCD24860.1 - 3.8e-06 26.8 7.2 3.8e-06 26.8 7.2 2.6 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CCD24860.1 - 1.8e-05 24.5 5.4 1.8e-05 24.5 5.4 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CCD24860.1 - 0.01 15.9 2.4 0.01 15.9 2.4 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CCD24860.1 - 0.018 15.3 6.3 0.018 15.3 6.3 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-ACC PF17848.1 CCD24860.1 - 0.022 14.8 2.5 0.022 14.8 2.5 3.2 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf-RING_4 PF14570.6 CCD24860.1 - 0.029 14.1 14.5 0.14 11.9 6.5 3.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DHC PF09626.10 CCD24860.1 - 0.045 14.6 0.1 0.79 10.6 0.0 2.8 3 0 0 3 3 2 0 Dihaem cytochrome c zinc_ribbon_9 PF14369.6 CCD24860.1 - 0.27 11.5 13.7 2.2 8.6 1.3 3.3 2 1 0 2 2 2 0 zinc-ribbon zf-RING_6 PF14835.6 CCD24860.1 - 0.28 11.1 5.1 0.11 12.4 2.1 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DZR PF12773.7 CCD24860.1 - 0.33 11.0 10.7 2.3 8.3 1.1 2.8 2 2 0 2 2 2 0 Double zinc ribbon HypA PF01155.19 CCD24860.1 - 0.54 10.3 8.3 0.89 9.6 0.5 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MCR PF18509.1 CCD24860.1 - 2.1 8.0 5.6 8.4 6.1 0.3 2.7 2 0 0 2 2 2 0 Magnetochrome domain zf-RING_7 PF02591.15 CCD24860.1 - 2.2 8.5 6.1 8.7 6.6 1.0 3.9 2 1 1 3 3 3 0 C4-type zinc ribbon domain Zn-ribbon_8 PF09723.10 CCD24860.1 - 2.8 8.1 8.5 2.2 8.5 1.1 2.9 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_10 PF16685.5 CCD24860.1 - 4.1 7.6 8.0 0.77 9.9 2.8 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 ETRAMP PF09716.10 CCD24861.1 - 0.042 13.9 0.9 0.13 12.4 0.3 2.1 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) NlpE PF04170.12 CCD24861.1 - 0.19 12.7 2.0 6.2 7.9 1.6 2.5 2 0 0 2 2 2 0 NlpE N-terminal domain SLATT_fungal PF18142.1 CCD24862.1 - 0.22 11.5 2.6 0.28 11.2 2.6 1.5 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain RRM_1 PF00076.22 CCD24863.1 - 3.6e-23 81.2 1.3 3.3e-13 49.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD24863.1 - 0.0043 17.1 0.2 3 8.0 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CCD24863.1 - 0.0097 15.5 0.3 0.027 14.1 0.2 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VPS9 PF02204.18 CCD24863.1 - 0.14 12.4 0.9 0.32 11.2 0.9 1.6 1 1 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain AMP-binding PF00501.28 CCD24864.1 - 6.9e-86 288.5 0.0 9.3e-86 288.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCD24864.1 - 0.00023 22.0 0.0 0.0022 19.0 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Bac_rhodopsin PF01036.18 CCD24865.1 - 1.2e-57 195.0 16.3 1.4e-57 194.8 16.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.6 CCD24865.1 - 0.04 13.6 12.3 1.2 8.8 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Cation_efflux PF01545.21 CCD24866.1 - 1.8e-53 181.2 11.0 4.1e-53 180.1 11.0 1.5 1 1 0 1 1 1 1 Cation efflux family DUF1646 PF07854.12 CCD24866.1 - 0.026 13.9 1.8 0.034 13.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1646) Integrase_DNA PF02920.15 CCD24867.1 - 1.1 9.0 3.2 27 4.6 0.0 2.3 2 0 0 2 2 2 0 DNA binding domain of tn916 integrase Ribosomal_L18A PF01775.17 CCD24869.1 - 3.8e-53 178.7 1.2 5.2e-53 178.3 1.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DMT_YdcZ PF04657.13 CCD24870.1 - 0.047 14.0 0.8 0.094 13.0 0.1 1.8 2 0 0 2 2 2 0 Putative inner membrane exporter, YdcZ Nop PF01798.18 CCD24871.1 - 2.8e-81 272.3 0.3 2.8e-81 272.3 0.3 2.1 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CCD24871.1 - 1.2e-18 67.2 1.8 1.2e-18 67.2 1.8 2.5 2 1 0 2 2 2 1 NOP5NT (NUC127) domain DUF4604 PF15377.6 CCD24871.1 - 0.018 15.5 44.2 0.031 14.7 44.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RR_TM4-6 PF06459.12 CCD24871.1 - 4.3 7.1 30.8 11 5.8 30.8 1.8 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SART-1 PF03343.13 CCD24872.1 - 3.3e-53 181.2 44.9 5.3e-53 180.5 44.9 1.3 1 0 0 1 1 1 1 SART-1 family TPT PF03151.16 CCD24873.1 - 5.9e-23 81.6 28.0 8e-20 71.3 28.0 3.8 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CCD24873.1 - 4e-05 23.8 25.7 0.0022 18.2 8.6 3.7 3 1 1 4 4 4 3 EamA-like transporter family DUF1689 PF07954.11 CCD24873.1 - 0.15 12.5 0.3 0.33 11.3 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) MFS_1 PF07690.16 CCD24874.1 - 1e-24 87.1 27.9 2.3e-24 86.0 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCD24874.1 - 4.6e-09 35.6 26.4 5.3e-08 32.2 3.7 3.2 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 CCD24874.1 - 7.6e-05 21.7 12.4 0.0046 15.9 10.7 2.4 2 1 0 2 2 2 2 MFS_1 like family DUF4231 PF14015.6 CCD24874.1 - 0.036 14.5 0.7 0.81 10.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2076 PF09849.9 CCD24874.1 - 8.9 6.3 13.1 13 5.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2034 PF10356.9 CCD24875.1 - 3.6e-56 189.5 0.0 4.3e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 CCD24875.1 - 0.00012 22.1 0.0 0.28 11.2 0.0 2.2 2 0 0 2 2 2 2 Restriction endonuclease PCRF PF03462.18 CCD24876.1 - 0.18 11.6 3.6 0.2 11.5 3.6 1.0 1 0 0 1 1 1 0 PCRF domain SNF2_N PF00176.23 CCD24877.1 - 8.6e-76 254.9 0.7 1.9e-75 253.8 0.7 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 CCD24877.1 - 9.2e-40 135.2 5.7 9.2e-40 135.2 5.7 4.5 3 1 1 4 4 4 1 SLIDE HAND PF09110.11 CCD24877.1 - 7.2e-32 110.4 19.2 7.2e-32 110.4 19.2 5.6 6 1 0 6 6 6 1 HAND Helicase_C PF00271.31 CCD24877.1 - 2.2e-21 76.2 0.0 1.3e-18 67.4 0.0 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD24877.1 - 3.8e-12 46.5 0.1 3.8e-12 46.5 0.1 4.5 5 1 1 6 6 6 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCD24877.1 - 2.5e-05 24.1 0.0 7.4e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 CCD24877.1 - 0.073 13.3 0.1 3.5 7.9 0.0 3.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain OTCace_N PF02729.21 CCD24877.1 - 0.63 10.0 3.9 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 CCD24878.1 - 8.6e-49 165.9 0.0 1.2e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 CCD24878.1 - 1.9e-45 153.8 0.0 2.9e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 CCD24878.1 - 3.5e-05 23.7 0.2 0.00096 19.0 0.1 2.9 1 1 1 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 CCD24878.1 - 0.022 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family RGS PF00615.19 CCD24879.1 - 3.8e-05 23.9 1.0 0.0003 21.0 0.1 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain ChAPs PF09295.10 CCD24880.1 - 4.8e-160 532.9 2.0 6.8e-160 532.4 2.0 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 CCD24880.1 - 0.0081 16.7 0.1 7.4 7.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCD24880.1 - 0.052 14.1 0.7 0.36 11.4 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CCD24880.1 - 0.068 13.0 0.1 1.8 8.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CCD24880.1 - 0.069 13.3 4.5 0.16 12.1 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 CCD24880.1 - 0.085 13.3 0.4 0.3 11.5 0.4 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 CCD24880.1 - 0.15 13.0 0.0 87 4.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD24880.1 - 0.32 11.2 3.2 8.3 6.7 0.5 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Vps39_1 PF10366.9 CCD24880.1 - 2.4 8.5 6.1 2.2 8.6 3.1 2.5 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 Acyltransf_C PF16076.5 CCD24881.1 - 0.0016 18.5 0.3 0.0069 16.5 0.0 2.2 2 0 0 2 2 2 1 Acyltransferase C-terminus RB_B PF01857.20 CCD24881.1 - 0.042 13.9 3.1 0.11 12.6 0.1 2.7 2 1 0 2 2 2 0 Retinoblastoma-associated protein B domain Acyltransferase PF01553.21 CCD24881.1 - 0.095 12.3 0.0 0.29 10.8 0.0 1.8 1 1 0 1 1 1 0 Acyltransferase CybS PF05328.12 CCD24882.1 - 5e-41 139.5 0.0 6.6e-41 139.1 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Cauli_VI PF01693.16 CCD24883.1 - 8.1e-32 109.3 9.1 9.9e-16 57.8 5.2 2.3 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 CCD24883.1 - 3.1e-31 108.5 0.5 6.9e-31 107.4 0.0 1.8 2 0 0 2 2 2 1 RNase H Membr_traf_MHD PF10540.9 CCD24884.1 - 2.2e-35 122.1 0.9 8.5e-35 120.1 0.1 2.5 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 CCD24884.1 - 1.3e-11 44.7 0.0 3.1e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 CCD24884.1 - 1.1e-06 27.6 0.1 2.6e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) EST1 PF10374.9 CCD24884.1 - 7 7.3 8.8 24 5.6 0.3 3.7 3 1 0 4 4 4 0 Telomerase activating protein Est1 SWIB PF02201.18 CCD24885.1 - 3.4e-20 71.7 0.1 3.4e-20 71.7 0.1 2.7 3 0 0 3 3 3 1 SWIB/MDM2 domain DEK_C PF08766.11 CCD24885.1 - 0.00015 21.6 0.0 0.00064 19.6 0.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain CorA PF01544.18 CCD24885.1 - 0.05 12.9 1.1 0.12 11.7 1.1 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RRS1 PF04939.12 CCD24886.1 - 1.1e-58 197.6 4.7 1.3e-58 197.4 4.7 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) S10_plectin PF03501.15 CCD24887.1 - 2.3e-42 143.0 0.4 2.7e-42 142.8 0.4 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF4364 PF14277.6 CCD24887.1 - 0.018 14.8 0.2 0.028 14.2 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4364) HTH_45 PF14947.6 CCD24887.1 - 0.027 14.4 0.2 0.048 13.6 0.2 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix MsyB PF13984.6 CCD24887.1 - 0.055 13.8 0.0 0.07 13.4 0.0 1.3 1 0 0 1 1 1 0 MsyB protein tRNA-synt_1c_C PF03950.18 CCD24887.1 - 0.056 13.3 0.1 0.062 13.2 0.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain PadR PF03551.14 CCD24887.1 - 0.14 12.2 0.2 0.14 12.2 0.2 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Mpv17_PMP22 PF04117.12 CCD24888.1 - 1.2e-17 63.8 0.9 1.2e-17 63.8 0.9 2.8 4 0 0 4 4 4 1 Mpv17 / PMP22 family P5-ATPase PF12409.8 CCD24889.1 - 7.7e-36 123.0 0.1 2.4e-35 121.4 0.1 1.9 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 CCD24889.1 - 1.3e-29 103.0 0.0 2.6e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CCD24889.1 - 1.5e-14 54.8 0.0 3.4e-07 30.8 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCD24889.1 - 2.2e-05 24.5 0.0 4.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CCD24889.1 - 0.0027 17.5 0.1 5.3 6.7 0.0 3.7 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase Thioredoxin PF00085.20 CCD24891.1 - 1.1e-24 86.4 1.5 4.6e-24 84.4 1.3 2.1 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 CCD24891.1 - 2.3e-06 27.2 2.1 3.9e-06 26.4 2.1 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CCD24891.1 - 7.9e-05 23.1 0.2 0.00027 21.4 0.2 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 CCD24891.1 - 9.3e-05 22.3 0.6 0.00015 21.6 0.1 1.6 1 1 1 2 2 2 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 CCD24891.1 - 0.004 17.4 5.0 0.089 13.1 4.7 3.1 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 CCD24891.1 - 0.011 15.7 0.2 0.03 14.3 0.2 1.7 1 0 0 1 1 1 0 Thioredoxin domain AhpC-TSA PF00578.21 CCD24891.1 - 0.039 13.9 0.1 0.085 12.8 0.1 1.6 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.6 CCD24891.1 - 0.049 13.8 0.1 0.099 12.8 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like Orf78 PF06024.12 CCD24891.1 - 1.3 9.3 5.6 2.8 8.3 5.6 1.5 1 0 0 1 1 1 0 Orf78 (ac78) RRP36 PF06102.12 CCD24892.1 - 7.9e-36 123.5 25.7 7.9e-36 123.5 25.7 2.4 1 1 1 2 2 2 1 rRNA biogenesis protein RRP36 Inositol_P PF00459.25 CCD24892.1 - 8 5.9 7.1 14 5.1 7.1 1.5 1 0 0 1 1 1 0 Inositol monophosphatase family Rhodanese PF00581.20 CCD24893.1 - 7.1e-11 42.6 0.0 9.8e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 CCD24894.1 - 6.4e-16 58.8 0.0 8.3e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain His_Phos_1 PF00300.22 CCD24895.1 - 1.1e-40 139.5 0.0 1.2e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Phosducin PF02114.16 CCD24896.1 - 5.3e-07 28.8 4.7 4.2e-06 25.9 4.7 2.0 1 1 0 1 1 1 1 Phosducin DUF3141 PF11339.8 CCD24896.1 - 0.14 10.5 0.3 0.21 10.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) UCH PF00443.29 CCD24897.1 - 1e-50 172.6 13.2 1.3e-50 172.3 13.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CCD24897.1 - 9e-10 38.7 5.5 9e-10 38.7 5.5 4.3 4 2 1 5 5 5 1 Zn-finger in ubiquitin-hydrolases and other protein FSH1 PF03959.13 CCD24898.1 - 2.4e-66 223.4 0.0 3.5e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CCD24898.1 - 0.0097 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 CCD24898.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1281_C PF18406.1 CCD24898.1 - 0.086 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein HEM4 PF02602.15 CCD24900.1 - 5.8e-46 156.7 0.0 6.6e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD PIF1 PF05970.14 CCD24900.1 - 0.033 13.3 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Oxidored_FMN PF00724.20 CCD24901.1 - 3.8e-127 424.3 0.0 4.3e-127 424.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GMP_synt_C PF00958.22 CCD24902.1 - 9.3e-45 150.6 0.0 1.8e-44 149.7 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 CCD24902.1 - 1.5e-40 139.0 0.0 2.7e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 CCD24902.1 - 4.8e-08 32.4 0.0 9.7e-06 24.9 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 CCD24902.1 - 2.7e-05 24.1 0.1 0.00023 21.0 0.0 2.4 2 1 0 2 2 2 1 Peptidase C26 QueC PF06508.13 CCD24902.1 - 0.014 14.9 0.0 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 CCD24902.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family tRNA_Me_trans PF03054.16 CCD24902.1 - 0.038 12.8 0.1 0.079 11.7 0.0 1.5 2 0 0 2 2 2 0 tRNA methyl transferase MetJ PF01340.20 CCD24902.1 - 0.051 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Met Apo-repressor, MetJ Arginosuc_synth PF00764.19 CCD24902.1 - 0.069 12.4 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ThiI PF02568.14 CCD24902.1 - 0.075 12.6 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) DnaJ PF00226.31 CCD24903.1 - 4.7e-26 90.7 6.6 4.7e-26 90.7 6.6 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_C PF01556.18 CCD24903.1 - 3.7e-20 72.5 0.0 4.9e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CCD24903.1 - 1.7e-15 57.1 20.8 3.2e-15 56.2 20.8 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CCD24903.1 - 2.1e-06 27.6 10.0 0.0001 22.2 1.3 2.3 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CCD24903.1 - 0.013 15.5 9.0 0.2 11.7 0.5 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrome_C7 PF14522.6 CCD24903.1 - 0.23 11.5 9.6 2.3 8.3 9.6 2.3 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c zf-CHY PF05495.12 CCD24903.1 - 0.82 10.2 6.7 1.7 9.2 6.7 1.5 1 0 0 1 1 1 0 CHY zinc finger TackOD1 PF18551.1 CCD24903.1 - 2.9 7.5 7.8 5 6.8 0.9 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zinc-ribbons_6 PF07191.12 CCD24903.1 - 6.3 6.8 8.3 16 5.6 8.3 1.6 1 1 0 1 1 1 0 zinc-ribbons DZR PF12773.7 CCD24903.1 - 9.3 6.4 10.7 69 3.6 11.0 2.0 1 1 0 1 1 1 0 Double zinc ribbon CAF20 PF17052.5 CCD24904.1 - 1.5e-55 187.7 1.1 1.8e-55 187.5 1.1 1.1 1 0 0 1 1 1 1 Cap associated factor BRO1 PF03097.18 CCD24905.1 - 4e-97 325.5 7.8 4e-97 325.5 7.8 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CCD24905.1 - 1.6e-29 103.2 19.6 6.6e-17 61.7 13.8 2.5 3 0 0 3 3 3 2 ALIX V-shaped domain binding to HIV Elf4 PF07011.11 CCD24905.1 - 0.096 12.6 3.8 3.5 7.6 0.1 3.1 2 0 0 2 2 2 0 Early Flowering 4 domain YlbD_coat PF14071.6 CCD24905.1 - 0.23 11.7 8.2 0.26 11.5 6.5 2.0 2 0 0 2 2 2 0 Putative coat protein RRP14 PF15459.6 CCD24905.1 - 0.48 11.1 4.3 0.22 12.2 1.3 2.1 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 IPPT PF01715.17 CCD24906.1 - 2e-67 227.4 0.2 2e-67 227.4 0.2 1.6 2 0 0 2 2 2 1 IPP transferase IPT PF01745.16 CCD24906.1 - 4.1e-05 23.1 0.1 0.00037 20.0 0.0 2.5 3 0 0 3 3 3 1 Isopentenyl transferase AAA_33 PF13671.6 CCD24906.1 - 0.0022 18.2 0.1 0.0066 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CCD24906.1 - 0.0037 16.6 0.3 0.16 11.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 CCD24906.1 - 0.005 17.4 0.0 0.025 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CCD24906.1 - 0.031 14.2 0.4 0.093 12.6 0.1 1.9 2 0 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 CCD24906.1 - 0.041 14.3 0.1 0.17 12.3 0.0 2.1 2 0 0 2 2 1 0 RNA helicase Cytidylate_kin PF02224.18 CCD24906.1 - 0.047 13.4 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase ParA PF10609.9 CCD24906.1 - 0.058 12.8 0.5 0.24 10.8 0.4 1.9 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase Hpr_kinase_C PF07475.12 CCD24906.1 - 0.14 11.7 0.1 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain T2SSE PF00437.20 CCD24906.1 - 0.14 11.2 0.2 0.27 10.2 0.2 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 CCD24906.1 - 0.19 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 CCD24906.1 - 0.24 11.5 0.5 0.6 10.2 0.5 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 CCD24906.1 - 8.2 6.9 6.0 6.3 7.3 2.2 2.5 2 1 0 2 2 2 0 ABC transporter NLE PF08154.12 CCD24907.1 - 2.3e-24 85.7 0.2 5.7e-24 84.4 0.2 1.7 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 CCD24907.1 - 1.2e-23 82.9 12.1 6.7e-07 29.9 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 CCD24907.1 - 8.8e-09 34.5 7.3 0.00023 19.9 0.2 3.7 2 2 1 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CCD24907.1 - 0.0062 16.8 0.3 0.089 13.1 0.0 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCD24907.1 - 0.049 13.0 0.6 0.5 9.6 0.2 2.4 2 1 0 2 2 2 0 WD40-like domain Phyto-Amp PF15438.6 CCD24907.1 - 0.98 9.2 4.9 0.24 11.2 0.2 2.3 3 1 0 3 3 3 0 Antigenic membrane protein of phytoplasma PYST-C1 PF09690.10 CCD24907.1 - 6.9 6.5 9.0 3.7 7.4 4.2 2.5 2 0 0 2 2 2 0 Plasmodium yoelii subtelomeric region (PYST-C1) Hyphal_reg_CWP PF11765.8 CCD24908.1 - 5.3e-37 127.5 13.1 5.3e-37 127.5 13.1 1.4 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal B_lectin PF01453.24 CCD24908.1 - 3.5 8.2 5.7 5.2 7.7 3.0 2.6 2 1 0 2 2 2 0 D-mannose binding lectin Mtc PF03820.17 CCD24909.1 - 4.3e-119 397.2 0.3 4.8e-119 397.0 0.3 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier V_ATPase_I PF01496.19 CCD24910.1 - 0 1018.7 5.5 0 1018.5 5.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family GIT_CC PF16559.5 CCD24910.1 - 0.003 17.4 0.3 0.0079 16.0 0.3 1.6 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor WD40 PF00400.32 CCD24911.1 - 3.8e-21 75.0 16.3 1.5e-05 25.6 0.5 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.8 CCD24911.1 - 3.6e-06 25.9 0.7 0.055 12.1 0.1 2.8 3 0 0 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CCD24911.1 - 0.0021 18.3 0.2 1.6 9.1 0.1 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain AKNA PF12443.8 CCD24911.1 - 0.0077 16.9 0.0 0.021 15.4 0.0 1.7 2 0 0 2 2 2 1 AT-hook-containing transcription factor DUF2205 PF10224.9 CCD24911.1 - 0.025 14.6 0.3 0.06 13.4 0.3 1.6 1 0 0 1 1 1 0 Short coiled-coil protein WD40_like PF17005.5 CCD24911.1 - 0.028 13.8 2.3 0.43 9.9 0.1 2.9 2 1 0 3 3 3 0 WD40-like domain PQQ_3 PF13570.6 CCD24911.1 - 0.14 12.7 0.0 0.67 10.5 0.0 2.2 1 0 0 1 1 1 0 PQQ-like domain Pkinase PF00069.25 CCD24912.1 - 1.2e-46 159.3 0.2 7e-43 146.9 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24912.1 - 1.8e-18 66.8 0.0 6.5e-18 64.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD24912.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.4 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 CCD24912.1 - 0.035 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CDC45 PF02724.14 CCD24912.1 - 4 5.6 12.3 0.021 13.1 2.9 1.9 2 1 0 2 2 2 0 CDC45-like protein TBCA PF02970.16 CCD24914.1 - 1.5e-26 92.5 11.3 1.6e-26 92.5 10.6 1.4 1 1 0 1 1 1 1 Tubulin binding cofactor A Cytochrom_C_2 PF01322.20 CCD24914.1 - 0.017 16.0 1.1 0.026 15.4 1.1 1.3 1 1 0 1 1 1 0 Cytochrome C' Fzo_mitofusin PF04799.13 CCD24914.1 - 0.022 14.3 2.8 0.03 13.9 2.8 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF1910 PF08928.10 CCD24914.1 - 0.046 13.7 2.6 0.063 13.3 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) FapA PF03961.13 CCD24914.1 - 0.17 10.4 8.1 0.19 10.3 8.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 CCD24914.1 - 0.29 10.0 11.5 0.64 8.8 11.5 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein PdaC PF13739.6 CCD24914.1 - 1.4 9.9 8.0 0.79 10.7 3.7 2.0 1 1 1 2 2 2 0 Deacetylase PdaC ATP_bind_1 PF03029.17 CCD24916.1 - 1.2e-81 274.1 0.1 1.5e-81 273.7 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 CCD24916.1 - 0.0012 19.4 0.1 0.32 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 CCD24916.1 - 0.089 11.8 0.2 0.18 10.7 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 CCD24916.1 - 0.11 12.8 0.1 0.32 11.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CCD24916.1 - 0.11 12.9 0.0 0.31 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 CCD24916.1 - 0.12 12.8 3.1 0.3 11.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain HUN PF08729.10 CCD24916.1 - 0.15 12.1 3.4 0.51 10.4 3.4 2.0 1 1 0 1 1 1 0 HPC2 and ubinuclein domain Fucokinase PF07959.12 CCD24917.1 - 5.1e-05 22.4 0.7 0.00015 20.8 0.7 1.8 1 0 0 1 1 1 1 L-fucokinase Hexapep PF00132.24 CCD24917.1 - 0.00072 19.2 1.5 0.012 15.4 1.4 2.6 1 1 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CCD24917.1 - 0.00088 19.7 0.0 0.0014 19.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 CCD24917.1 - 0.0032 15.7 0.3 0.0032 15.7 0.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 CCD24917.1 - 0.083 12.7 3.5 4.3 7.2 1.9 2.7 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase AAA PF00004.29 CCD24918.1 - 1.5e-42 145.2 0.0 3e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CCD24918.1 - 2e-08 34.0 0.3 4.8e-08 32.8 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CCD24918.1 - 7.2e-08 32.1 0.2 2.6e-07 30.3 0.1 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 CCD24918.1 - 6.7e-07 29.8 2.9 7.6e-05 23.2 0.0 3.2 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CCD24918.1 - 6.4e-06 26.2 3.5 4.3e-05 23.5 0.2 3.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CCD24918.1 - 3.2e-05 24.1 0.0 8.6e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CCD24918.1 - 6.8e-05 22.7 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 CCD24918.1 - 0.00018 21.5 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CCD24918.1 - 0.0018 18.6 0.2 0.032 14.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 CCD24918.1 - 0.0023 18.3 0.0 0.0051 17.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 CCD24918.1 - 0.0025 17.1 0.1 0.0049 16.1 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CCD24918.1 - 0.0065 15.9 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CCD24918.1 - 0.0068 17.0 0.2 0.034 14.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CCD24918.1 - 0.008 16.4 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CCD24918.1 - 0.012 15.4 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Fib_alpha PF08702.10 CCD24918.1 - 0.014 15.6 3.1 0.032 14.4 3.1 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA_24 PF13479.6 CCD24918.1 - 0.014 15.1 0.0 0.039 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CCD24918.1 - 0.026 14.8 0.3 0.068 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 CCD24918.1 - 0.03 14.0 0.1 0.099 12.3 0.0 1.8 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_14 PF13173.6 CCD24918.1 - 0.043 13.9 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CCD24918.1 - 0.051 13.1 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 CCD24918.1 - 0.059 12.8 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 CCD24918.1 - 0.063 12.8 0.1 0.19 11.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CCD24918.1 - 0.067 12.5 1.6 0.11 11.8 0.0 2.2 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.17 CCD24918.1 - 0.071 12.2 0.1 0.16 11.0 0.1 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 CCD24918.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CCD24918.1 - 0.15 12.0 0.1 0.51 10.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 CCD24918.1 - 0.15 11.8 7.1 0.95 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain HIT PF01230.23 CCD24919.1 - 2.4e-18 66.7 0.6 1.6e-17 64.0 0.3 2.1 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 CCD24919.1 - 2.5e-16 60.2 3.0 9.6e-16 58.3 3.0 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 CCD24919.1 - 2.9e-13 50.1 1.1 5.9e-13 49.1 1.1 1.5 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_4 PF13894.6 CCD24919.1 - 0.058 14.3 1.4 0.058 14.3 1.4 3.1 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CCD24919.1 - 0.77 10.1 6.8 1.2 9.5 5.2 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) EF-hand_1 PF00036.32 CCD24920.1 - 2.5e-29 98.6 16.7 5.9e-08 31.7 1.7 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CCD24920.1 - 7.2e-24 84.0 14.7 1.2e-13 51.3 2.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCD24920.1 - 9.9e-23 78.1 15.2 5.8e-07 28.9 0.6 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CCD24920.1 - 4.1e-16 58.6 16.1 1.2e-11 44.3 3.1 3.5 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 CCD24920.1 - 6.7e-12 45.6 0.6 5.4e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CCD24920.1 - 1.1e-11 43.7 24.2 9.1e-06 24.9 0.3 5.1 4 2 1 5 5 5 3 EF hand EF-hand_4 PF12763.7 CCD24920.1 - 0.00036 20.4 7.2 0.12 12.4 0.3 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 CCD24920.1 - 0.00085 19.6 3.7 0.16 12.3 0.3 2.2 1 1 1 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 CCD24920.1 - 0.021 15.0 1.9 0.36 11.1 0.4 2.6 2 1 1 3 3 3 0 Dockerin type I domain SurA_N_2 PF13623.6 CCD24920.1 - 0.023 14.6 0.7 0.51 10.2 0.1 2.6 1 1 2 3 3 3 0 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 CCD24920.1 - 0.043 14.1 3.7 2.9 8.3 0.4 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_3 PF13624.6 CCD24920.1 - 0.066 13.0 0.6 0.36 10.6 0.1 2.0 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_13 PF17958.1 CCD24920.1 - 0.11 12.3 0.1 9 6.2 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain Caleosin PF05042.13 CCD24920.1 - 0.13 12.2 3.4 6 6.8 0.1 3.4 1 1 3 4 4 4 0 Caleosin related protein PhetRS_B1 PF18262.1 CCD24920.1 - 1.2 9.4 8.5 0.3 11.3 1.0 2.9 2 1 2 4 4 4 0 Phe-tRNA synthetase beta subunit B1 domain VCBS PF13517.6 CCD24920.1 - 6.9 7.3 6.8 9.9 6.8 0.4 3.0 3 2 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TFR_dimer PF04253.15 CCD24921.1 - 6.7e-26 90.8 1.0 3.5e-24 85.2 0.5 2.5 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CCD24921.1 - 7e-05 22.6 0.0 0.00017 21.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 Tetraspanin PF00335.20 CCD24921.1 - 0.024 14.3 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetraspanin family Acetyltransf_1 PF00583.25 CCD24922.1 - 8.9e-11 42.1 0.0 1.2e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCD24922.1 - 1.2e-10 41.4 0.1 1.7e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCD24922.1 - 2.9e-10 40.4 0.1 4.2e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CCD24922.1 - 0.00062 19.9 0.1 0.00072 19.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCD24922.1 - 0.023 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DUF4222 PF13973.6 CCD24922.1 - 0.066 12.8 0.1 3.5 7.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4222) Acetyltransf_9 PF13527.7 CCD24922.1 - 0.08 13.0 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 CCD24922.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tma16 PF11176.8 CCD24923.1 - 9.5e-47 158.5 4.6 1.2e-46 158.2 4.6 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Rhodanese PF00581.20 CCD24924.1 - 3.1e-17 63.0 0.0 1.3e-08 35.3 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain CLP1_P PF16575.5 CCD24925.1 - 6.5e-29 101.1 0.0 1.2e-28 100.2 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 CCD24925.1 - 1.7e-24 86.5 0.0 3.3e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 CCD24925.1 - 2.1e-21 75.9 0.0 4.2e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor PduV-EutP PF10662.9 CCD24925.1 - 0.0077 16.0 0.0 0.027 14.2 0.0 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 CCD24925.1 - 0.0094 16.0 0.1 0.028 14.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase TcdA_TcdB PF12919.7 CCD24925.1 - 0.022 14.1 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain FtsK_SpoIIIE PF01580.18 CCD24925.1 - 0.025 13.9 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 CCD24925.1 - 0.031 14.5 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CCD24925.1 - 0.058 13.8 0.0 0.12 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CCD24925.1 - 0.068 12.9 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CCD24925.1 - 0.073 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CCD24925.1 - 0.14 12.6 0.0 0.46 10.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase ANAPC5 PF12862.7 CCD24926.1 - 2.7e-27 94.6 6.9 2.7e-27 94.6 6.9 3.0 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 5 Augurin PF15187.6 CCD24926.1 - 0.0012 19.0 0.1 0.022 14.9 0.0 2.6 3 0 0 3 3 3 1 Oesophageal cancer-related gene 4 DUF4294 PF14127.6 CCD24926.1 - 0.016 15.2 0.3 0.075 12.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) TPR_8 PF13181.6 CCD24926.1 - 0.041 14.1 0.7 20 5.7 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCD24926.1 - 0.075 13.3 0.0 12 6.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3791 PF12668.7 CCD24926.1 - 0.16 12.1 4.1 6.1 7.0 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3791) DUF1694 PF07997.11 CCD24926.1 - 0.17 12.0 2.5 0.65 10.1 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1694) Tugs PF17840.1 CCD24928.1 - 0.11 12.7 0.0 33 4.8 0.0 3.0 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain Gal4_dimer PF03902.13 CCD24928.1 - 7.4 6.8 7.0 2.7 8.2 0.1 3.7 4 1 0 4 4 4 0 Gal4-like dimerisation domain adh_short PF00106.25 CCD24929.1 - 1.9e-20 73.2 0.0 4.1e-18 65.5 0.0 3.0 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCD24929.1 - 5.9e-12 45.6 0.0 4.4e-10 39.5 0.0 2.5 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCD24929.1 - 0.017 15.1 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 KR domain tRNA-synt_1 PF00133.22 CCD24930.1 - 2.5e-43 148.2 0.0 1.9e-34 118.9 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CCD24930.1 - 8.5e-17 61.0 0.1 1.5e-09 37.1 0.0 3.9 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CCD24930.1 - 3.5e-12 46.5 0.0 8.7e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CCD24930.1 - 4.2e-07 29.6 0.0 1.6e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DUF2157 PF09925.9 CCD24931.1 - 0.2 11.5 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DAGAT PF03982.13 CCD24932.1 - 8.3e-81 271.1 0.4 4.9e-72 242.3 0.0 2.1 1 1 1 2 2 2 2 Diacylglycerol acyltransferase MOZ_SAS PF01853.18 CCD24933.1 - 1.4e-81 272.4 0.2 2.2e-81 271.8 0.2 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CCD24933.1 - 2.7e-21 74.9 0.2 8.1e-21 73.4 0.2 1.9 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CCD24933.1 - 2.2e-20 72.3 0.6 4.5e-20 71.3 0.6 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CCD24933.1 - 0.0014 19.0 0.0 0.0037 17.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CCD24933.1 - 0.0042 17.3 0.0 0.04 14.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family TruD PF01142.18 CCD24934.1 - 5.3e-75 252.8 0.6 1e-69 235.4 0.3 3.1 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Mur_ligase_M PF08245.12 CCD24936.1 - 2.4e-06 27.7 0.9 0.00021 21.3 0.0 3.0 2 1 1 3 3 3 2 Mur ligase middle domain Mur_ligase_C PF02875.21 CCD24936.1 - 0.0039 17.4 0.0 0.013 15.7 0.0 1.9 1 1 1 2 2 2 1 Mur ligase family, glutamate ligase domain NRN1 PF15056.6 CCD24936.1 - 0.1 12.7 0.0 0.44 10.7 0.0 2.0 2 0 0 2 2 2 0 Neuritin protein family Methyltransf_12 PF08242.12 CCD24937.1 - 3.5e-14 53.4 0.1 2.5e-13 50.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCD24937.1 - 3.6e-12 46.4 0.0 5.6e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCD24937.1 - 2.5e-10 40.9 0.0 9.4e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCD24937.1 - 1.5e-07 31.9 0.0 3.5e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCD24937.1 - 1.6e-05 24.7 0.1 6.3e-05 22.8 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CCD24937.1 - 0.021 14.0 0.0 3 6.9 0.0 2.4 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_32 PF13679.6 CCD24937.1 - 0.18 11.8 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF3298 PF11738.8 CCD24937.1 - 2.2 9.4 5.2 18 6.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3298) DUF1749 PF08538.10 CCD24939.1 - 2.7e-95 318.9 0.0 3e-95 318.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 CCD24939.1 - 9.2e-07 28.4 0.0 2.2e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCD24939.1 - 8.4e-05 22.3 0.0 0.003 17.3 0.0 2.4 2 1 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CCD24939.1 - 0.00011 21.8 0.0 0.00032 20.2 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CCD24939.1 - 0.00014 22.6 0.0 0.00019 22.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 CCD24939.1 - 0.0048 16.5 0.3 0.022 14.3 0.1 1.9 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Ndr PF03096.14 CCD24939.1 - 0.0087 14.8 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 CCD24939.1 - 0.05 13.3 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 CCD24939.1 - 0.064 12.8 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 CCD24939.1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase SPA PF08616.10 CCD24939.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis DUF900 PF05990.12 CCD24939.1 - 0.1 12.1 0.2 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) AbiH PF14253.6 CCD24939.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Lipase_3 PF01764.25 CCD24939.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 CCD24939.1 - 0.16 10.9 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme ABC_membrane_2 PF06472.15 CCD24940.1 - 3e-82 276.0 6.9 3e-82 276.0 6.9 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CCD24940.1 - 3e-13 50.4 0.0 1.1e-12 48.6 0.0 2.0 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CCD24940.1 - 0.00069 19.1 0.5 0.027 13.9 0.5 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DEAD PF00270.29 CCD24940.1 - 0.024 14.4 0.0 0.23 11.2 0.0 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_23 PF13476.6 CCD24940.1 - 0.3 11.6 4.0 1.7 9.1 4.0 2.3 1 1 0 1 1 1 0 AAA domain Oxysterol_BP PF01237.18 CCD24941.1 - 3.2e-56 190.8 3.4 7.8e-54 182.9 3.4 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DHFR_1 PF00186.19 CCD24942.1 - 9.6e-27 93.7 0.0 1.7e-26 92.9 0.0 1.4 2 0 0 2 2 2 1 Dihydrofolate reductase POC3_POC4 PF10448.9 CCD24943.1 - 4.7e-17 62.4 0.3 5.7e-17 62.1 0.3 1.1 1 0 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 PAC4 PF16093.5 CCD24943.1 - 0.00014 22.0 0.0 0.0002 21.5 0.0 1.5 1 1 0 1 1 1 1 Proteasome assembly chaperone 4 Ribosomal_L35Ae PF01247.18 CCD24944.1 - 1.4e-42 143.7 1.4 1.6e-42 143.5 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CCD24944.1 - 0.0035 17.5 0.0 2 8.7 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Pkinase PF00069.25 CCD24945.1 - 1.9e-64 217.6 0.0 3.3e-64 216.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24945.1 - 3.3e-38 131.5 0.0 5.6e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD24945.1 - 2e-08 33.9 0.0 3.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCD24945.1 - 0.0056 16.6 0.1 0.012 15.5 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CCD24945.1 - 0.0092 15.6 0.0 0.025 14.2 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CCD24945.1 - 0.029 13.7 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3951 PF13131.6 CCD24945.1 - 0.041 14.1 0.1 0.093 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) GrpE PF01025.19 CCD24946.1 - 3.5e-50 169.9 9.7 4.4e-50 169.6 9.7 1.1 1 0 0 1 1 1 1 GrpE Uds1 PF15456.6 CCD24946.1 - 0.00086 19.5 1.1 0.0015 18.7 1.1 1.5 1 0 0 1 1 1 1 Up-regulated During Septation TACC_C PF05010.14 CCD24946.1 - 0.0025 17.6 13.7 0.15 11.8 0.3 2.1 2 0 0 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal OmpH PF03938.14 CCD24946.1 - 0.031 14.6 15.9 0.028 14.8 15.0 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 CCD24946.1 - 0.47 9.5 6.6 0.63 9.1 6.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Syntaxin_2 PF14523.6 CCD24946.1 - 0.77 10.2 10.8 2.1 8.8 10.8 1.7 1 1 0 1 1 1 0 Syntaxin-like protein DUF1451 PF07295.11 CCD24946.1 - 0.82 9.7 6.5 1.2 9.2 6.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF883 PF05957.13 CCD24946.1 - 1.2 9.7 6.8 0.63 10.7 3.7 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) UPF0242 PF06785.11 CCD24946.1 - 1.3 9.1 10.2 1.8 8.6 10.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus O-antigen_lig PF13425.6 CCD24946.1 - 1.5 7.5 3.3 2.4 6.8 3.3 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein HIP1_clath_bdg PF16515.5 CCD24946.1 - 2 9.1 13.8 3.1 8.5 11.2 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 CCD24946.1 - 4.3 6.6 12.0 7 5.9 11.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 CCD24947.1 - 2.5e-73 246.7 0.0 3.6e-73 246.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24947.1 - 1.9e-35 122.4 0.0 3.9e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD24947.1 - 5.7e-08 32.4 0.0 1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CCD24947.1 - 0.00052 19.7 0.1 0.26 10.9 0.2 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CCD24947.1 - 0.0034 16.2 0.0 0.0065 15.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 CCD24947.1 - 0.0087 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 CCD24947.1 - 0.026 13.9 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CCD24947.1 - 0.087 11.7 3.2 0.3 10.0 3.2 2.0 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CCD24947.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 CCD24948.1 - 3.5e-05 24.5 5.3 0.041 14.8 0.2 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat WD40 PF00400.32 CCD24949.1 - 0.0011 19.7 10.3 0.017 16.0 0.5 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat PHTB1_N PF14727.6 CCD24949.1 - 0.067 12.5 0.0 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 PTHB1 N-terminus Tam41_Mmp37 PF09139.11 CCD24950.1 - 1.1e-92 311.0 10.6 5.1e-86 289.0 2.2 2.8 2 1 1 3 3 3 2 Phosphatidate cytidylyltransferase, mitochondrial DUF1691 PF07950.11 CCD24951.1 - 2.1e-20 73.4 0.3 4.3e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.22 CCD24951.1 - 0.00068 19.7 0.2 0.049 13.7 0.4 2.2 2 0 0 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NifU_N PF01592.16 CCD24953.1 - 3.7e-56 188.8 0.3 4.4e-56 188.5 0.3 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 CCD24953.1 - 0.0032 17.7 0.2 0.0059 16.8 0.2 1.4 1 0 0 1 1 1 1 TSCPD domain RNA_pol_Rpb8 PF03870.15 CCD24954.1 - 7.7e-46 155.7 0.1 8.7e-46 155.6 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CCD24954.1 - 0.00059 19.9 0.9 0.36 10.9 0.2 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G TcpA PF05946.12 CCD24954.1 - 0.15 12.2 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA DUF2407_C PF13373.6 CCD24955.1 - 4.1e-45 153.4 1.7 9.6e-45 152.2 1.7 1.6 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 CCD24955.1 - 7.2e-20 71.5 0.3 7.2e-20 71.5 0.3 1.9 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rep_N PF08724.10 CCD24955.1 - 0.013 15.2 0.1 0.021 14.6 0.1 1.2 1 0 0 1 1 1 0 Rep protein catalytic domain like Mito_carr PF00153.27 CCD24956.1 - 2.9e-62 206.6 0.6 2e-23 82.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 CCD24956.1 - 0.0049 17.2 0.4 0.019 15.3 0.3 2.3 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PT-VENN PF04829.13 CCD24956.1 - 0.43 10.7 3.6 22 5.2 0.2 3.2 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif HTH_51 PF18558.1 CCD24958.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain LapA_dom PF06305.11 CCD24959.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain ATG22 PF11700.8 CCD24959.1 - 0.014 14.1 0.0 0.016 13.9 0.0 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like COX6C PF02937.15 CCD24959.1 - 0.045 13.9 0.1 0.072 13.2 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc RFC1 PF08519.12 CCD24960.1 - 7.1e-59 198.5 0.3 5.1e-58 195.7 0.1 2.2 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 CCD24960.1 - 4.1e-12 46.7 0.0 1.3e-11 45.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 CCD24960.1 - 8.2e-12 45.3 0.0 2.4e-11 43.9 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 CCD24960.1 - 3.4e-05 23.9 0.0 9.4e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CCD24960.1 - 4.2e-05 23.4 0.0 9.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCD24960.1 - 0.00035 21.0 0.0 0.0016 18.8 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 CCD24960.1 - 0.00036 20.7 0.0 0.0011 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 CCD24960.1 - 0.0011 19.2 0.0 0.0037 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 CCD24960.1 - 0.0017 18.6 0.0 0.0093 16.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCD24960.1 - 0.0039 17.7 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CCD24960.1 - 0.012 16.1 0.0 0.012 16.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CCD24960.1 - 0.012 16.0 0.0 0.041 14.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 CCD24960.1 - 0.046 13.8 0.0 0.26 11.3 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CCD24960.1 - 0.066 13.2 0.1 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) GRAB PF10375.9 CCD24961.1 - 5.7e-07 29.2 1.6 1.5e-06 27.9 1.6 1.8 1 0 0 1 1 1 1 GRIP-related Arf-binding domain CENP-F_leu_zip PF10473.9 CCD24961.1 - 0.00072 19.6 22.2 0.00072 19.6 22.2 4.9 1 1 3 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Telomere_reg-2 PF10193.9 CCD24961.1 - 6.4 7.3 13.0 0.083 13.3 1.9 3.2 2 1 0 3 3 3 0 Telomere length regulation protein YqeY PF09424.10 CCD24962.1 - 1.9e-22 79.9 5.7 2.4e-22 79.6 5.7 1.1 1 0 0 1 1 1 1 Yqey-like protein FRB_dom PF08771.11 CCD24962.1 - 0.01 16.2 1.9 0.031 14.7 1.0 2.2 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain DUF3489 PF11994.8 CCD24962.1 - 0.03 14.4 0.1 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3489) DNTTIP1_dimer PF18192.1 CCD24962.1 - 0.034 14.5 4.9 0.43 11.0 0.0 2.8 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain PP2C_C PF07830.13 CCD24962.1 - 0.5 10.9 4.5 5.5 7.5 0.2 2.6 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain YEATS PF03366.16 CCD24964.1 - 2.4e-19 69.1 0.0 3.7e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 YEATS family BET PF17035.5 CCD24964.1 - 2.7e-06 27.5 0.0 5.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation YEATS PF03366.16 CCD24965.1 - 1.6e-19 69.6 0.1 8.7e-19 67.3 0.0 2.1 2 0 0 2 2 2 1 YEATS family WD40 PF00400.32 CCD24966.1 - 1.9e-27 95.0 25.4 6e-05 23.7 0.4 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD24966.1 - 3.8e-11 43.1 0.2 0.15 12.3 0.0 4.8 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCD24966.1 - 0.00093 18.6 0.4 0.22 10.8 0.0 2.6 2 0 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 CCD24966.1 - 0.0036 16.3 1.5 4.6 6.1 0.0 3.7 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LXG PF04740.12 CCD24966.1 - 0.016 14.9 1.7 0.03 14.0 1.7 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily Golgin_A5 PF09787.9 CCD24966.1 - 0.08 12.4 2.3 0.11 11.9 2.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF5082 PF16888.5 CCD24966.1 - 0.2 11.9 5.1 0.52 10.6 5.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Linker_histone PF00538.19 CCD24967.1 - 3.1e-44 149.2 2.0 2.1e-22 79.2 0.0 3.0 3 0 0 3 3 3 2 linker histone H1 and H5 family Dynamin_N PF00350.23 CCD24968.1 - 2.1e-42 145.0 0.1 2.1e-42 145.0 0.1 3.0 4 0 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.23 CCD24968.1 - 3e-05 24.1 0.1 0.00028 20.9 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.20 CCD24968.1 - 0.017 14.3 10.5 0.033 13.4 0.1 3.0 3 0 0 3 3 3 0 Dynamin central region AAA_16 PF13191.6 CCD24968.1 - 0.086 13.2 0.4 0.57 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 CCD24968.1 - 0.1 12.8 0.0 0.35 11.1 0.0 2.0 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase HTH_18 PF12833.7 CCD24968.1 - 0.16 12.3 1.9 0.38 11.1 0.7 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain RNA_pol_N PF01194.17 CCD24969.1 - 9.5e-30 102.7 0.5 1.1e-29 102.5 0.5 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 CCD24969.1 - 0.059 13.6 0.2 0.079 13.2 0.2 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) NAPRTase PF04095.16 CCD24970.1 - 4.9e-70 235.9 0.0 6.7e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 CCD24970.1 - 8.9e-32 110.1 0.5 2.3e-31 108.8 0.5 1.7 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain RNA_pol_Rpb2_6 PF00562.28 CCD24971.1 - 2.8e-125 418.5 0.1 4.8e-125 417.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CCD24971.1 - 3.3e-63 212.9 1.1 2.5e-62 210.0 1.1 2.0 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CCD24971.1 - 4.2e-42 143.9 2.3 9.8e-42 142.7 2.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CCD24971.1 - 1.4e-33 115.2 2.4 2.4e-33 114.4 0.2 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CCD24971.1 - 2.3e-26 91.8 0.2 8.1e-26 90.1 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CCD24971.1 - 1.6e-18 66.7 0.0 4.4e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CCD24971.1 - 4.9e-10 39.8 0.2 4.9e-10 39.8 0.2 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 DUF5315 PF17242.2 CCD24972.1 - 1.1e-20 73.2 0.1 2.6e-20 72.0 0.1 1.7 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) DUF4942 PF13708.6 CCD24972.1 - 0.19 11.7 3.6 1.4 8.8 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4942) Noc2 PF03715.13 CCD24973.1 - 3.7e-128 427.0 6.5 4.9e-128 426.6 5.1 1.9 2 0 0 2 2 2 1 Noc2p family MMR_HSR1 PF01926.23 CCD24974.1 - 5.6e-07 29.7 0.1 4.1e-06 26.8 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCD24974.1 - 1.4e-05 25.1 0.5 2.4e-05 24.3 0.1 1.6 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CCD24974.1 - 0.0012 18.4 0.6 0.57 9.7 0.2 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CCD24974.1 - 0.0073 16.4 0.4 0.15 12.1 0.0 2.9 3 0 0 3 3 3 1 Dynamin family ABC_tran PF00005.27 CCD24974.1 - 0.023 15.2 0.0 0.053 14.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DEAD PF00270.29 CCD24975.1 - 4.1e-49 166.7 0.0 8.4e-49 165.7 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD24975.1 - 7.1e-32 110.0 0.0 1.4e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CCD24975.1 - 0.015 14.6 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 CCD24975.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 CCD24975.1 - 0.18 11.8 0.0 0.58 10.1 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit IGPD PF00475.18 CCD24976.1 - 2.8e-60 202.8 0.4 5.9e-60 201.7 0.5 1.4 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase DUF3943 PF13084.6 CCD24976.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) HemS PF05171.12 CCD24976.1 - 0.077 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Haemin-degrading HemS.ChuX domain NUMOD3 PF07460.11 CCD24976.1 - 0.15 12.3 0.2 0.26 11.5 0.2 1.4 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) SpoU_methylase PF00588.19 CCD24977.1 - 3.1e-23 82.5 0.0 6.6e-20 71.7 0.0 3.0 3 0 0 3 3 3 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 CCD24977.1 - 1e-15 57.8 0.1 1.8e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Peptidase_C14 PF00656.22 CCD24979.1 - 1.1e-64 218.8 0.1 1.4e-64 218.4 0.1 1.1 1 0 0 1 1 1 1 Caspase domain LIAS_N PF16881.5 CCD24980.1 - 6.3e-17 62.0 0.3 1.8e-16 60.5 0.3 1.8 1 1 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 CCD24980.1 - 6.6e-15 55.9 0.1 1.2e-14 55.0 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Spore_GerAC PF05504.11 CCD24980.1 - 0.073 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal DLH PF01738.18 CCD24981.1 - 8.8e-23 81.0 0.0 1e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CCD24981.1 - 0.0073 15.8 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family 6PF2K PF01591.18 CCD24981.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase LIDHydrolase PF10230.9 CCD24981.1 - 0.2 11.2 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Pyr_redox_2 PF07992.14 CCD24982.1 - 3.2e-50 171.0 0.0 4e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCD24982.1 - 2.5e-13 50.4 0.0 4e-11 43.3 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCD24982.1 - 2.5e-05 23.7 0.0 0.13 11.5 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Fzo_mitofusin PF04799.13 CCD24982.1 - 0.012 15.1 1.3 0.015 14.9 0.2 1.7 2 0 0 2 2 2 0 fzo-like conserved region Ldh_1_N PF00056.23 CCD24983.1 - 1.5e-40 138.6 0.0 2.9e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CCD24983.1 - 1.5e-39 135.7 0.1 2.2e-39 135.1 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 CCD24983.1 - 0.00039 19.5 0.0 0.0015 17.6 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CCD24983.1 - 0.0098 16.3 0.0 0.028 14.8 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Vps4_C PF09336.10 CCD24984.1 - 0.0072 16.3 2.2 0.55 10.3 0.8 2.5 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain DUF3201 PF11447.8 CCD24984.1 - 0.023 14.2 0.1 0.046 13.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3201) DUF775 PF05603.12 CCD24984.1 - 0.032 13.8 1.4 0.05 13.1 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Pkinase PF00069.25 CCD24985.1 - 6e-65 219.2 0.0 7.6e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD24985.1 - 1.1e-27 97.0 0.0 1.5e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCD24985.1 - 0.0039 17.2 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCD24985.1 - 0.046 12.5 0.1 0.73 8.5 0.1 2.2 1 1 0 1 1 1 0 Fungal protein kinase TPP_enzyme_N PF02776.18 CCD24986.1 - 1.7e-29 102.6 0.0 3.2e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCD24986.1 - 1.6e-20 73.3 0.0 3.1e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCD24986.1 - 5.3e-13 49.0 0.0 1.2e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NUC153 PF08159.12 CCD24986.1 - 0.061 13.1 0.1 11 5.9 0.0 3.0 3 0 0 3 3 3 0 NUC153 domain Diphthamide_syn PF01866.17 CCD24986.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative diphthamide synthesis protein Ribosomal_60s PF00428.19 CCD24987.1 - 8e-23 80.8 10.6 9.7e-23 80.6 10.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein WRNPLPNID PF15017.6 CCD24987.1 - 0.036 15.0 0.2 0.054 14.4 0.2 1.3 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Ribosomal_L13e PF01294.18 CCD24988.1 - 2.1e-67 226.4 4.2 3.6e-67 225.7 4.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_S9 PF00380.19 CCD24989.1 - 2.9e-32 111.7 0.1 3.3e-32 111.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DHDPS PF00701.22 CCD24990.1 - 0.054 12.2 0.2 6.3 5.4 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate synthetase family Amidase PF01425.21 CCD24990.1 - 0.11 11.4 0.8 0.16 10.9 0.8 1.3 1 0 0 1 1 1 0 Amidase PKcGMP_CC PF16808.5 CCD24990.1 - 0.45 10.4 7.7 0.24 11.3 3.3 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1967 PF09269.11 CCD24990.1 - 1.1 9.2 5.2 12 6.0 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1967) DivIC PF04977.15 CCD24990.1 - 3.5 7.5 12.4 0.17 11.7 3.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Plasmo_rep PF12135.8 CCD24990.1 - 4.8 6.8 8.3 5.7 6.6 0.7 2.9 3 0 0 3 3 3 0 Plasmodium repeat family DEAD PF00270.29 CCD24991.1 - 4.2e-35 121.1 0.0 8e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD24991.1 - 4.7e-28 97.8 0.1 1.1e-25 90.1 0.1 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CCD24991.1 - 5.8e-08 32.9 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ANAPC_CDC26 PF10471.9 CCD24991.1 - 0.14 13.0 0.2 0.33 11.8 0.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Macoilin PF09726.9 CCD24992.1 - 9.2 4.7 10.4 10 4.5 10.4 1.1 1 0 0 1 1 1 0 Macoilin family SRP1_TIP1 PF00660.17 CCD24993.1 - 2.9e-11 43.3 0.3 2.9e-11 43.3 0.3 2.2 2 1 1 3 3 3 1 Seripauperin and TIP1 family Alpha_GJ PF03229.13 CCD24993.1 - 0.19 12.3 0.3 0.19 12.3 0.3 2.5 2 1 0 2 2 2 0 Alphavirus glycoprotein J RIC1 PF07064.13 CCD24994.1 - 9e-12 44.9 0.3 3e-11 43.2 0.3 1.9 1 1 0 1 1 1 1 RIC1 COX6B PF02297.17 CCD24995.1 - 4.5e-20 71.7 4.8 5.9e-20 71.3 4.8 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.14 CCD24995.1 - 0.097 12.6 0.4 0.14 12.1 0.4 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain MYT1 PF08474.11 CCD24995.1 - 0.18 11.7 0.2 0.17 11.8 0.2 1.1 1 0 0 1 1 1 0 Myelin transcription factor 1 DNA_mis_repair PF01119.19 CCD24996.1 - 2.3e-11 43.4 0.1 5.6e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CCD24996.1 - 1.7e-09 37.6 0.1 4.7e-09 36.2 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CCD24996.1 - 1.1e-06 29.2 0.1 3.2e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EF-hand_6 PF13405.6 CCD24996.1 - 0.044 13.7 0.0 0.24 11.4 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain Nramp PF01566.18 CCD24997.1 - 7.3e-96 321.2 12.5 1e-95 320.8 12.5 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Bromodomain PF00439.25 CCD24998.1 - 4.7e-06 26.6 1.9 3.4e-05 23.8 1.8 2.4 1 1 0 1 1 1 1 Bromodomain FSA_C PF10479.9 CCD24998.1 - 7.9 4.5 10.7 11 3.9 10.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus HA2 PF04408.23 CCD24999.1 - 3.1e-28 98.2 0.0 3.1e-28 98.2 0.0 2.9 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CCD24999.1 - 1.1e-14 54.6 0.0 3.6e-14 52.9 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CCD24999.1 - 1.3e-13 51.3 1.2 1.7e-10 41.3 0.0 3.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCD24999.1 - 9.3e-08 32.0 0.0 2.5e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCD24999.1 - 0.00014 22.2 0.4 0.00051 20.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CCD24999.1 - 0.00056 19.1 0.0 0.0012 17.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 CCD24999.1 - 0.0016 18.2 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CCD24999.1 - 0.008 15.5 3.3 0.0088 15.4 0.0 2.6 3 0 0 3 3 3 1 KaiC DUF4704 PF15787.5 CCD24999.1 - 0.017 14.4 0.9 0.031 13.5 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) AAA_19 PF13245.6 CCD24999.1 - 0.021 15.2 0.0 0.048 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CCD24999.1 - 0.056 12.9 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein HTH_37 PF13744.6 CCD24999.1 - 0.067 13.2 2.2 0.1 12.6 0.2 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain SNF2_N PF00176.23 CCD25000.1 - 5.9e-67 225.9 0.0 9.1e-67 225.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 CCD25000.1 - 5.1e-15 55.2 0.0 1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 CCD25000.1 - 2.5e-13 50.3 0.0 1.2e-12 48.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 CCD25000.1 - 1.3e-08 35.1 7.1 2.3e-08 34.2 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CCD25000.1 - 1.3e-07 31.4 4.1 2.2e-07 30.6 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCD25000.1 - 1.2e-06 28.4 8.5 2.2e-06 27.5 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CCD25000.1 - 8.1e-06 25.6 8.7 1.8e-05 24.5 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 CCD25000.1 - 2e-05 24.7 0.0 0.00022 21.3 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 CCD25000.1 - 2.6e-05 24.2 5.7 5.5e-05 23.1 5.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CCD25000.1 - 0.0008 19.2 5.6 0.0015 18.3 5.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CCD25000.1 - 0.0064 16.3 7.1 0.013 15.3 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCD25000.1 - 0.019 15.1 8.8 0.041 14.0 8.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING KLRAQ PF10205.9 CCD25000.1 - 0.043 14.0 0.4 0.15 12.3 0.4 2.0 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein zf-RING_6 PF14835.6 CCD25000.1 - 0.045 13.6 2.8 0.11 12.4 2.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FANCL_C PF11793.8 CCD25000.1 - 0.1 12.8 4.6 0.26 11.5 4.6 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_11 PF17123.5 CCD25000.1 - 0.11 12.2 5.6 0.25 11.1 5.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 CCD25000.1 - 0.22 11.8 4.1 0.52 10.6 4.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CCD25000.1 - 0.29 11.0 6.8 0.61 9.9 6.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Scm3 PF10384.9 CCD25000.1 - 1.9 8.3 4.7 2.4 7.9 0.4 3.2 3 0 0 3 3 3 0 Centromere protein Scm3 PHD PF00628.29 CCD25000.1 - 5 7.1 6.3 10 6.1 6.3 1.6 1 0 0 1 1 1 0 PHD-finger MIF4G_like PF09088.11 CCD25001.1 - 1e-54 185.2 0.7 2.4e-54 184.0 0.7 1.7 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 CCD25001.1 - 1.9e-45 155.5 1.1 2.3e-40 138.8 0.2 2.5 1 1 1 2 2 2 2 MIF4G like DUF1493 PF07377.12 CCD25001.1 - 4.8 7.7 7.8 0.56 10.7 0.6 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1493) Ribosomal_L15e PF00827.17 CCD25002.1 - 9.1e-89 296.2 12.7 1.1e-88 296.0 12.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 zf-C3HC4_3 PF13920.6 CCD25003.1 - 8.1e-07 28.8 12.7 1.4e-06 28.0 12.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF5426 PF17473.2 CCD25003.1 - 2.3 8.5 12.9 1.5 9.1 3.8 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5426) Prok-RING_4 PF14447.6 CCD25003.1 - 3 7.8 12.0 5.9 6.8 12.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 AICARFT_IMPCHas PF01808.18 CCD25004.1 - 8.2e-92 307.8 0.0 1.3e-91 307.2 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CCD25004.1 - 3e-24 85.0 0.0 6.6e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain Oxidored_FMN PF00724.20 CCD25005.1 - 1.5e-120 402.6 0.0 1.7e-120 402.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF5442 PF17514.2 CCD25005.1 - 0.089 13.0 0.0 0.95 9.7 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5442) adh_short PF00106.25 CCD25006.1 - 3.1e-16 59.4 0.0 3.4e-14 52.8 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 CCD25006.1 - 8.8e-09 35.5 0.1 1.7e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 CCD25006.1 - 3.4e-07 30.1 0.0 1.9e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CCD25006.1 - 9.1e-07 28.6 0.0 1.2e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CCD25006.1 - 0.0028 17.1 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CCD25006.1 - 0.21 10.7 0.1 0.88 8.6 0.0 2.0 2 1 0 2 2 2 0 RmlD substrate binding domain Aminotran_1_2 PF00155.21 CCD25007.1 - 1.2e-80 271.4 0.0 1.4e-80 271.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SNARE PF05739.19 CCD25008.1 - 1.3e-15 57.1 0.8 4.1e-15 55.5 0.8 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 CCD25008.1 - 1.5e-08 33.6 1.1 2.9e-08 32.7 1.1 1.5 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 CCD25008.1 - 0.00037 20.2 0.6 0.00037 20.2 0.6 3.4 2 1 1 3 3 3 2 Syntaxin Syntaxin-18_N PF10496.9 CCD25008.1 - 0.002 18.3 2.7 0.002 18.3 2.7 2.8 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus DUF16 PF01519.16 CCD25008.1 - 0.014 15.9 1.4 0.014 15.9 1.4 3.2 3 0 0 3 3 3 0 Protein of unknown function DUF16 DUF1664 PF07889.12 CCD25008.1 - 1 9.4 13.0 2.1 8.4 0.6 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Spt20 PF12090.8 CCD25008.1 - 1.1 8.9 21.3 0.18 11.4 8.4 2.3 2 0 0 2 2 2 0 Spt20 family MCPsignal PF00015.21 CCD25008.1 - 1.2 9.0 10.6 0.12 12.2 0.6 2.7 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Snf7 PF03357.21 CCD25009.1 - 7e-49 165.7 20.5 7e-49 165.7 20.5 2.0 2 0 0 2 2 2 1 Snf7 NuA4 PF09340.10 CCD25009.1 - 0.0027 17.6 0.6 0.012 15.5 0.6 2.1 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 IF3_C PF00707.22 CCD25009.1 - 0.024 14.6 0.8 0.057 13.4 0.6 1.9 1 1 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain NOG1 PF06858.14 CCD25009.1 - 0.38 10.6 0.1 0.38 10.6 0.1 2.6 3 0 0 3 3 3 0 Nucleolar GTP-binding protein 1 (NOG1) Snapin_Pallidin PF14712.6 CCD25009.1 - 4.4 7.8 15.5 0.87 10.0 6.9 3.1 1 1 2 3 3 3 0 Snapin/Pallidin DUF948 PF06103.11 CCD25009.1 - 4.8 7.5 7.3 4.6 7.6 1.0 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sdh_cyt PF01127.22 CCD25010.1 - 1.5e-19 70.2 4.7 2.1e-19 69.7 4.7 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit JUPITER PF17054.5 CCD25010.1 - 0.098 12.1 0.7 0.11 11.9 0.7 1.1 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter Abhydrolase_1 PF00561.20 CCD25011.1 - 2e-29 103.0 0.3 5.5e-29 101.6 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 CCD25011.1 - 2.3e-22 78.3 0.1 5.3e-22 77.2 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CCD25011.1 - 4e-05 23.0 0.0 0.00081 18.7 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 CCD25011.1 - 0.0029 17.3 0.1 2.8 7.6 0.0 2.4 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CCD25011.1 - 0.0053 16.6 0.1 0.41 10.4 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Pkinase PF00069.25 CCD25012.1 - 4.2e-68 229.6 0.1 6.7e-68 228.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25012.1 - 5.7e-27 94.6 0.2 1.3e-19 70.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCD25012.1 - 0.00013 21.4 0.1 0.0007 19.0 0.0 2.4 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CCD25012.1 - 0.026 13.9 0.2 1.7 7.9 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2441 PF10386.9 CCD25012.1 - 0.082 12.9 1.2 2.9 7.9 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2441) DASH_Hsk3 PF08227.11 CCD25013.1 - 7.6e-20 71.0 3.5 9.2e-20 70.7 3.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Synaptonemal_3 PF15191.6 CCD25013.1 - 0.0035 17.1 0.3 0.0049 16.6 0.3 1.2 1 0 0 1 1 1 1 Synaptonemal complex central element protein 3 DUF4618 PF15397.6 CCD25013.1 - 0.016 14.7 0.4 0.016 14.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) FlxA PF14282.6 CCD25013.1 - 0.11 12.5 3.4 0.13 12.2 3.4 1.1 1 0 0 1 1 1 0 FlxA-like protein UPF0449 PF15136.6 CCD25013.1 - 0.15 12.5 1.9 0.2 12.2 1.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 L31 PF09784.9 CCD25014.1 - 2.4e-43 146.7 7.4 1.7e-42 144.0 7.4 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L31 Cmc1 PF08583.10 CCD25015.1 - 3.5e-19 68.6 3.0 4.5e-19 68.2 3.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 CCD25015.1 - 0.54 10.3 5.1 2.6 8.1 0.4 2.1 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF3128 PF11326.8 CCD25015.1 - 1.5 9.2 5.8 25 5.3 3.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3128) Adaptin_N PF01602.20 CCD25016.1 - 1e-128 430.2 15.4 1.3e-128 429.9 15.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CCD25016.1 - 5.4e-55 185.9 12.2 3.3e-53 180.1 4.4 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCD25016.1 - 9.5e-14 51.6 0.1 1e-05 25.8 0.1 5.7 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 CCD25016.1 - 2.3e-07 30.5 4.0 0.046 14.0 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 CCD25016.1 - 0.016 15.7 0.4 1.8 9.2 0.0 4.3 5 1 1 6 6 6 0 HEAT-like repeat RTP1_C1 PF10363.9 CCD25016.1 - 0.027 14.6 6.1 0.69 10.1 0.1 5.0 3 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 CCD25016.1 - 0.028 14.0 1.5 3 7.3 0.0 3.5 3 1 0 3 3 3 0 CLASP N terminal Atx10homo_assoc PF09759.9 CCD25016.1 - 0.052 13.6 1.9 0.42 10.6 0.1 3.2 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain TAN PF11640.8 CCD25016.1 - 0.18 11.9 1.0 31 4.7 0.0 3.2 3 0 0 3 3 3 0 Telomere-length maintenance and DNA damage repair Arm PF00514.23 CCD25016.1 - 0.37 10.9 1.4 14 5.9 0.1 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Peptidase_M3 PF01432.20 CCD25017.1 - 2.8e-136 455.5 0.0 4.1e-136 454.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 CCD25017.1 - 0.1 12.2 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Mur_ligase_M PF08245.12 CCD25018.1 - 7.8e-07 29.3 0.0 2.3e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CCD25018.1 - 0.03 14.6 0.0 0.068 13.4 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain She2p PF11435.8 CCD25019.1 - 7.6e-87 290.2 15.7 9.6e-87 289.9 15.7 1.1 1 0 0 1 1 1 1 RNA binding protein She2p Ist1 PF03398.14 CCD25019.1 - 0.0078 16.2 0.2 0.018 15.0 0.2 1.6 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Myosin_head PF00063.21 CCD25020.1 - 7.2e-234 778.0 10.2 9.2e-234 777.6 10.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CCD25020.1 - 3.7e-45 153.9 0.4 7.9e-45 152.8 0.4 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 CCD25020.1 - 2.2e-11 43.2 0.0 4.5e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCD25020.1 - 9.5e-08 31.8 0.0 2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCD25020.1 - 1.4e-06 27.9 0.0 3.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain RsgA_GTPase PF03193.16 CCD25020.1 - 0.014 15.4 0.1 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF4047 PF13256.6 CCD25020.1 - 0.025 14.8 1.9 0.12 12.6 1.9 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) AAA_16 PF13191.6 CCD25020.1 - 0.027 14.9 0.0 0.095 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 CCD25020.1 - 0.029 13.9 0.1 9.6 5.7 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 CCD25020.1 - 0.045 14.0 0.0 0.2 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CCD25020.1 - 0.066 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain IQ PF00612.27 CCD25020.1 - 0.85 9.6 14.7 2.4 8.2 6.2 2.8 1 1 1 2 2 2 0 IQ calmodulin-binding motif TPP_enzyme_N PF02776.18 CCD25021.1 - 5.1e-54 182.5 0.4 1.3e-53 181.1 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CCD25021.1 - 8.8e-50 168.5 0.1 4.8e-48 162.8 0.0 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCD25021.1 - 3.1e-40 137.1 0.7 1.5e-39 134.8 0.3 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain His_Phos_1 PF00300.22 CCD25022.1 - 6.8e-09 35.7 0.0 0.00019 21.2 0.0 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) SPG4 PF17325.2 CCD25023.1 - 1.5e-41 141.9 4.8 1.6e-41 141.8 4.8 1.0 1 0 0 1 1 1 1 Stationary phase protein 4 DUF2590 PF10761.9 CCD25023.1 - 0.16 12.1 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2590) PGM_PMM_III PF02880.16 CCD25024.1 - 4.4e-27 94.5 0.0 6.8e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CCD25024.1 - 1.6e-06 28.2 0.0 3.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Kinesin PF00225.23 CCD25025.1 - 1.4e-103 346.3 4.4 2.6e-103 345.5 3.9 1.7 1 1 1 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CCD25025.1 - 5.2e-23 81.6 0.3 5.2e-23 81.6 0.3 2.8 3 0 0 3 3 3 1 Microtubule binding PKcGMP_CC PF16808.5 CCD25025.1 - 0.0046 16.8 1.5 0.0046 16.8 1.5 3.5 3 0 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Fib_alpha PF08702.10 CCD25025.1 - 0.015 15.5 3.2 0.015 15.5 3.2 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Rootletin PF15035.6 CCD25025.1 - 0.35 10.9 8.6 0.3 11.1 3.8 2.4 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Wtap PF17098.5 CCD25025.1 - 1.1 9.2 10.7 0.4 10.6 0.4 3.2 4 0 0 4 4 4 0 WTAP/Mum2p family CENP-H PF05837.12 CCD25025.1 - 1.4 9.3 7.3 20 5.7 0.1 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) CENP-F_leu_zip PF10473.9 CCD25025.1 - 4.2 7.4 12.1 9.6 6.2 0.4 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3589 PF12141.8 CCD25026.1 - 1.4e-73 248.2 2.9 1.6e-47 162.3 0.0 2.5 1 1 1 2 2 2 2 Beta-mannosyltransferases YtzH PF14165.6 CCD25026.1 - 0.42 11.0 3.6 0.16 12.4 0.3 2.0 2 0 0 2 2 2 0 YtzH-like protein Asp PF00026.23 CCD25027.1 - 4.4e-104 348.3 0.0 5.2e-104 348.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCD25027.1 - 5.7e-15 56.0 0.2 2.8e-13 50.5 0.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CCD25027.1 - 0.00021 21.1 0.0 0.00083 19.2 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Ribosomal_L27_C PF18471.1 CCD25027.1 - 0.25 10.7 0.0 0.37 10.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal L27 protein C-terminal domain Pkinase PF00069.25 CCD25028.1 - 2.9e-79 266.2 0.1 1.2e-78 264.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25028.1 - 1.6e-37 129.2 0.0 3.2e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CCD25028.1 - 1.4e-25 89.4 4.1 2.1e-13 50.4 0.3 3.2 3 0 0 3 3 3 2 FHA domain Yop-YscD_cpl PF16697.5 CCD25028.1 - 6.6e-08 32.8 0.0 6.7e-05 23.1 0.0 2.9 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 CCD25028.1 - 8.9e-06 25.2 0.0 2.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CCD25028.1 - 2.1e-05 24.0 0.0 3.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCD25028.1 - 5.6e-05 23.2 0.1 0.0074 16.2 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family FHA_2 PF17913.1 CCD25028.1 - 9.3e-05 22.6 0.6 0.051 13.8 0.0 3.6 3 0 0 3 3 3 1 FHA domain RIO1 PF01163.22 CCD25028.1 - 0.0068 16.0 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Mei5 PF10376.9 CCD25029.1 - 1.9e-14 54.0 21.7 1.9e-14 54.0 21.7 2.1 1 1 1 2 2 2 1 Double-strand recombination repair protein Homeodomain PF00046.29 CCD25029.1 - 0.0042 16.9 0.8 0.046 13.6 0.1 2.5 2 0 0 2 2 2 1 Homeodomain BACK PF07707.15 CCD25029.1 - 0.035 14.2 4.9 0.7 10.0 0.3 2.8 2 1 1 3 3 3 0 BTB And C-terminal Kelch Iron_permease PF04120.12 CCD25029.1 - 3.2 7.5 7.8 0.76 9.6 2.7 2.4 2 1 0 2 2 2 0 Low affinity iron permease Tfb2 PF03849.14 CCD25030.1 - 2.3e-139 464.3 0.9 3e-139 464.0 0.9 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 CCD25030.1 - 5.6e-23 81.1 0.4 1.4e-22 79.9 0.4 1.7 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 CCD25030.1 - 0.00011 22.3 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AHD PF17793.1 CCD25030.1 - 0.032 14.0 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 ANC1 homology domain (AHD) Ribonuclease_T2 PF00445.18 CCD25031.1 - 2e-37 129.2 0.6 2e-37 129.2 0.6 1.9 2 0 0 2 2 2 1 Ribonuclease T2 family DUF5474 PF17568.2 CCD25031.1 - 0.072 13.2 0.3 0.24 11.5 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5474) FPP PF05911.11 CCD25032.1 - 0.0015 16.8 7.1 0.0023 16.2 7.1 1.3 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil MAGSP PF03082.14 CCD25032.1 - 0.004 16.8 7.0 0.0098 15.5 7.0 1.6 1 0 0 1 1 1 1 Male accessory gland secretory protein CENP-F_leu_zip PF10473.9 CCD25032.1 - 0.061 13.3 6.6 0.12 12.4 6.6 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.11 CCD25032.1 - 0.31 9.7 6.4 0.028 13.1 2.0 1.4 2 0 0 2 2 2 0 Weak chloroplast movement under blue light Tmemb_cc2 PF10267.9 CCD25032.1 - 0.8 8.8 16.4 0.15 11.2 11.8 2.0 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF724 PF05266.14 CCD25032.1 - 0.93 9.3 8.5 0.36 10.6 5.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) HIP1_clath_bdg PF16515.5 CCD25032.1 - 3.4 8.3 8.5 0.94 10.1 3.9 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Y_phosphatase PF00102.27 CCD25033.1 - 6.7e-56 189.5 16.2 3.1e-53 180.8 2.9 3.1 3 0 0 3 3 3 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CCD25033.1 - 0.0041 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CCD25033.1 - 0.12 12.2 0.0 0.12 12.2 0.0 3.1 3 1 0 3 3 3 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CCD25033.1 - 0.14 12.3 1.8 3.2 7.9 0.0 3.0 3 0 0 3 3 3 0 Inositol hexakisphosphate IBN_N PF03810.19 CCD25034.1 - 8.1e-17 60.9 0.5 2.9e-16 59.1 0.5 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CCD25034.1 - 0.00056 20.0 0.1 0.00056 20.0 0.1 4.7 3 1 0 4 4 4 1 Exportin 1-like protein Mog1 PF04603.12 CCD25034.1 - 0.0028 18.0 0.2 0.012 16.0 0.2 2.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein NAPRTase PF04095.16 CCD25035.1 - 5e-74 248.9 0.0 6.5e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 CCD25035.1 - 1.8e-34 118.8 0.1 4.1e-34 117.7 0.1 1.7 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain WD40 PF00400.32 CCD25036.1 - 3.5e-05 24.5 3.6 0.015 16.2 0.0 5.1 5 0 0 5 5 5 1 WD domain, G-beta repeat Linker_histone PF00538.19 CCD25037.1 - 1.5e-49 166.2 10.9 7.7e-25 87.1 0.2 3.0 3 0 0 3 3 3 2 linker histone H1 and H5 family MSC PF09402.10 CCD25037.1 - 0.0017 17.9 1.9 0.47 9.8 0.1 2.2 1 1 1 2 2 2 2 Man1-Src1p-C-terminal domain DUF2207 PF09972.9 CCD25037.1 - 0.0032 16.3 7.7 0.0032 16.3 7.7 1.8 1 1 0 2 2 2 1 Predicted membrane protein (DUF2207) Dicty_REP PF05086.12 CCD25037.1 - 0.0066 14.5 12.9 0.01 13.9 12.9 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein TetR_C_24 PF17932.1 CCD25037.1 - 0.017 15.4 0.0 3.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Corona_M PF01635.18 CCD25037.1 - 3.6 6.8 9.8 5.6 6.2 9.8 1.3 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein TRF PF08558.10 CCD25038.1 - 1.1e-78 264.2 0.3 1.8e-78 263.5 0.3 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 CCD25038.1 - 8.7e-09 35.4 0.5 3.7e-08 33.4 0.5 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain UCR_Fe-S_N PF10399.9 CCD25038.1 - 0.0012 18.1 1.4 0.0027 17.0 1.4 1.6 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Myb_DNA-bind_6 PF13921.6 CCD25038.1 - 0.0026 18.0 1.9 0.0032 17.7 0.1 2.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain DUF573 PF04504.14 CCD25038.1 - 0.15 12.8 0.7 0.42 11.3 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF573 FAM60A PF15396.6 CCD25038.1 - 4.6 7.2 7.5 0.89 9.5 2.5 2.1 2 0 0 2 2 2 0 Protein Family FAM60A YEATS PF03366.16 CCD25039.1 - 6e-21 74.2 0.2 1e-20 73.5 0.2 1.4 1 0 0 1 1 1 1 YEATS family BET PF17035.5 CCD25039.1 - 3.7e-06 27.0 0.1 7.2e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF2457 PF10446.9 CCD25040.1 - 0.48 9.5 27.5 0.66 9.1 27.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) YL1 PF05764.13 CCD25040.1 - 1.6 8.8 20.2 2.4 8.2 20.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Macoilin PF09726.9 CCD25040.1 - 5 5.6 17.1 6.5 5.2 17.1 1.1 1 0 0 1 1 1 0 Macoilin family DPPIV_N PF00930.21 CCD25041.1 - 1.4e-89 300.4 6.1 1.9e-89 299.9 6.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CCD25041.1 - 1.1e-53 181.8 0.1 2.2e-53 180.9 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 CCD25041.1 - 0.00032 20.4 0.0 0.00074 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 CCD25041.1 - 0.00043 20.9 0.0 0.015 15.9 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CCD25041.1 - 0.0031 17.4 0.0 0.88 9.3 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CCD25041.1 - 0.018 14.3 0.0 2.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 AXE1 PF05448.12 CCD25041.1 - 0.024 13.3 0.1 1.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) PAF-AH_p_II PF03403.13 CCD25041.1 - 0.025 13.1 0.0 0.26 9.8 0.0 2.2 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 CCD25041.1 - 0.028 14.1 0.0 3.2 7.3 0.0 2.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold Ribosomal_L5e PF17144.4 CCD25042.1 - 1.2e-82 275.8 0.0 2.1e-82 275.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CCD25042.1 - 2.2e-31 108.6 1.3 2.2e-31 108.6 1.3 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.6 CCD25042.1 - 0.018 15.3 0.4 1.4 9.1 0.0 2.8 3 0 0 3 3 3 0 Threonine synthase N terminus Com_YlbF PF06133.11 CCD25042.1 - 0.028 15.0 1.2 0.062 13.9 1.2 1.6 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA Ribosomal_L18p PF00861.22 CCD25042.1 - 0.044 14.1 0.6 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast NAC PF01849.18 CCD25042.1 - 0.086 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NAC domain Phage_holin_3_3 PF16083.5 CCD25042.1 - 0.12 12.5 0.0 1.8 8.7 0.0 2.3 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III CtaG_Cox11 PF04442.14 CCD25043.1 - 2.6e-61 206.1 0.2 5.3e-61 205.1 0.0 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF3629 PF12302.8 CCD25043.1 - 0.03 13.8 0.1 0.044 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) Phage_TAC_5 PF08890.11 CCD25043.1 - 0.047 13.7 0.3 0.42 10.6 0.1 2.1 2 0 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC Ribosomal_S19e PF01090.19 CCD25043.1 - 0.094 12.4 0.2 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein S19e PRTP PF01366.18 CCD25043.1 - 0.21 9.6 0.0 0.3 9.1 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Zn_clus PF00172.18 CCD25044.1 - 8.4e-06 25.8 8.3 2.1e-05 24.5 8.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NifU_N PF01592.16 CCD25045.1 - 2.3e-56 189.5 0.7 4.1e-56 188.6 0.2 1.6 2 0 0 2 2 2 1 NifU-like N terminal domain TSCPD PF12637.7 CCD25045.1 - 0.037 14.3 0.2 0.068 13.4 0.2 1.4 1 0 0 1 1 1 0 TSCPD domain PHD PF00628.29 CCD25047.1 - 4.3e-12 45.7 6.0 9.9e-12 44.6 6.0 1.7 1 0 0 1 1 1 1 PHD-finger PIP49_C PF12260.8 CCD25047.1 - 0.013 15.1 0.6 0.027 14.1 0.6 1.5 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 BBS2_Mid PF14783.6 CCD25048.1 - 0.031 14.3 0.2 12 5.9 0.0 3.2 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 CCD25048.1 - 0.036 14.9 2.3 88 4.2 0.0 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Pkinase PF00069.25 CCD25049.1 - 5.8e-65 219.3 0.0 1.3e-64 218.1 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25049.1 - 4e-39 134.4 0.0 6.6e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD25049.1 - 3e-09 36.6 0.0 5.5e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCD25049.1 - 0.0067 16.4 0.1 0.016 15.1 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CCD25049.1 - 0.023 14.3 0.2 0.057 13.0 0.2 1.7 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CCD25049.1 - 0.098 12.0 0.6 0.31 10.4 0.6 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Oxysterol_BP PF01237.18 CCD25050.1 - 3.5e-61 207.1 2.0 5.2e-59 199.9 2.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Nop53 PF07767.11 CCD25051.1 - 1.7e-93 314.2 43.6 2e-93 314.0 43.6 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) W2 PF02020.18 CCD25051.1 - 0.067 13.3 10.8 0.79 9.9 1.4 2.8 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon TAF8_C PF10406.9 CCD25051.1 - 1.7 9.3 7.9 0.35 11.5 3.3 2.5 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term ACPS PF01648.20 CCD25052.1 - 6.3e-15 55.3 0.0 8.5e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily APG5 PF04106.12 CCD25054.1 - 1.4e-37 129.5 1.5 2.2e-36 125.6 1.5 2.0 1 1 0 1 1 1 1 Autophagy protein Apg5 SGT1 PF07093.11 CCD25055.1 - 7.2e-10 37.9 0.2 7.2e-10 37.9 0.2 2.2 2 0 0 2 2 2 1 SGT1 protein Pkinase PF00069.25 CCD25056.1 - 9.5e-69 231.7 0.0 1.5e-68 231.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25056.1 - 1.1e-37 129.8 0.0 1.7e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD25056.1 - 4.1e-09 36.2 0.0 7.6e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CCD25056.1 - 0.00011 21.2 0.0 0.00011 21.2 0.0 3.1 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CCD25056.1 - 0.093 12.1 0.0 0.37 10.1 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 CCD25057.1 - 3.9e-32 109.8 19.1 4.2e-06 27.4 0.6 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD25057.1 - 1.9e-05 24.9 0.9 0.72 10.2 0.1 3.9 2 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CCD25057.1 - 0.00013 20.9 0.8 1.8 7.2 0.0 4.1 1 1 3 4 4 4 3 Nup133 N terminal like WD40_like PF17005.5 CCD25057.1 - 0.047 13.0 0.0 4.7 6.5 0.0 2.6 2 1 0 2 2 2 0 WD40-like domain DUF4298 PF14131.6 CCD25057.1 - 0.13 12.2 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) SprB PF13573.6 CCD25057.1 - 1.5 8.7 4.3 0.49 10.2 0.5 2.1 2 0 0 2 2 2 0 SprB repeat PTPA PF03095.15 CCD25058.1 - 3.2e-114 381.4 0.6 3.7e-114 381.2 0.6 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF433 PF04255.14 CCD25058.1 - 0.21 11.4 0.2 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF433) APG6 PF04111.12 CCD25059.1 - 1e-61 208.0 0.0 2.2e-61 206.9 0.0 1.6 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 CCD25059.1 - 3.9e-27 95.4 18.7 3.9e-27 95.4 18.7 2.2 2 0 0 2 2 2 1 Apg6 coiled-coil region TPR_2 PF07719.17 CCD25059.1 - 0.011 15.8 1.0 3.5 8.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat YabA PF06156.13 CCD25059.1 - 0.036 14.7 9.6 0.14 12.8 4.4 2.7 2 0 0 2 2 2 0 Initiation control protein YabA TPR_6 PF13174.6 CCD25059.1 - 0.056 14.1 1.0 1.2 9.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Tweety PF04906.13 CCD25059.1 - 0.087 11.5 1.7 0.18 10.4 1.7 1.5 1 0 0 1 1 1 0 Tweety Herpes_UL6 PF01763.16 CCD25059.1 - 0.12 10.9 4.9 0.2 10.2 4.9 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like Noelin-1 PF12308.8 CCD25059.1 - 0.18 11.8 2.6 2.8 8.0 0.0 2.7 2 1 0 2 2 2 0 Neurogenesis glycoprotein LPP PF04728.13 CCD25059.1 - 0.32 11.4 5.2 1.2 9.5 0.0 3.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper FAM76 PF16046.5 CCD25059.1 - 0.37 10.1 9.6 0.73 9.1 9.6 1.4 1 0 0 1 1 1 0 FAM76 protein TPR_7 PF13176.6 CCD25059.1 - 0.67 10.1 2.1 4.6 7.5 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ATG16 PF08614.11 CCD25059.1 - 0.7 10.1 15.6 0.14 12.4 11.8 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Corona_S2 PF01601.16 CCD25059.1 - 2 6.8 5.1 1.7 7.1 3.7 1.4 1 1 0 1 1 1 0 Coronavirus S2 glycoprotein E2F_CC-MB PF16421.5 CCD25059.1 - 9 6.7 11.5 1.1 9.6 5.4 2.8 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain DEAD PF00270.29 CCD25060.1 - 1.6e-49 168.0 0.0 4.3e-49 166.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD25060.1 - 5.6e-33 113.6 0.0 1.8e-32 112.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD25060.1 - 0.00067 19.7 0.0 0.0016 18.5 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CCD25060.1 - 0.0099 15.1 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 CCD25060.1 - 0.025 13.9 0.0 0.059 12.7 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF844 PF05815.11 CCD25060.1 - 0.065 12.4 0.1 0.093 11.9 0.1 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Mit_ribos_Mrp51 PF11709.8 CCD25061.1 - 8.5e-68 229.6 3.0 2e-67 228.4 3.0 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit DUF188 PF02639.14 CCD25061.1 - 0.11 12.1 0.2 3.2 7.4 0.1 2.4 2 1 0 2 2 2 0 Uncharacterized BCR, YaiI/YqxD family COG1671 Cas_Cas2CT1978 PF09707.10 CCD25061.1 - 0.14 12.3 0.0 0.48 10.5 0.0 1.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) NUDIX PF00293.28 CCD25062.1 - 2.6e-25 89.0 0.0 4.2e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DASH_Dad1 PF08649.10 CCD25063.1 - 0.037 14.2 6.7 0.1 12.8 0.1 4.0 4 0 0 4 4 4 0 DASH complex subunit Dad1 HMA PF00403.26 CCD25063.1 - 0.044 14.2 0.5 0.044 14.2 0.5 3.8 4 0 0 4 4 4 0 Heavy-metal-associated domain MutS_II PF05188.17 CCD25063.1 - 1.6 9.0 19.1 1.7 8.9 1.1 3.7 3 0 0 3 3 3 0 MutS domain II PAS_10 PF13596.6 CCD25063.1 - 2.3 8.8 0.0 2.3 8.8 0.0 4.3 3 1 1 4 4 4 0 PAS domain Baculo_PEP_C PF04513.12 CCD25063.1 - 3.8 7.5 17.2 1.1 9.4 0.6 4.5 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bromodomain PF00439.25 CCD25063.1 - 4.1 7.5 8.1 29 4.8 0.2 4.0 4 0 0 4 4 4 0 Bromodomain Peptidase_C14 PF00656.22 CCD25064.1 - 2.5e-59 201.3 0.0 3.7e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Caspase domain TAL_effector PF03377.13 CCD25064.1 - 0.1 12.9 0.0 1.7 9.0 0.0 2.2 2 0 0 2 2 2 0 TAL effector repeat Hist_deacetyl PF00850.19 CCD25065.1 - 7.8e-53 179.9 0.1 7.8e-53 179.9 0.1 1.6 2 0 0 2 2 2 1 Histone deacetylase domain SF3a60_bindingd PF12108.8 CCD25065.1 - 0.13 12.2 0.1 0.32 10.9 0.1 1.7 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain RhoGAP PF00620.27 CCD25066.1 - 3.8e-36 124.2 1.8 6.2e-36 123.5 0.2 2.2 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 CCD25066.1 - 9.3e-13 48.6 0.7 4.2e-12 46.5 0.2 2.5 2 0 0 2 2 2 1 PH domain PX PF00787.24 CCD25066.1 - 0.0015 18.5 1.4 0.0047 16.9 0.5 2.4 2 0 0 2 2 2 1 PX domain PH_11 PF15413.6 CCD25066.1 - 0.0084 16.5 4.8 0.011 16.1 0.2 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain DUF4972 PF16342.5 CCD25066.1 - 0.75 9.5 5.4 10 5.8 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4972) TFIIA PF03153.13 CCD25067.1 - 9.5e-46 157.6 19.6 2e-24 87.4 14.3 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CCD25067.1 - 0.0043 15.9 1.8 0.0055 15.5 1.8 1.1 1 0 0 1 1 1 1 Presenilin Cwf_Cwc_15 PF04889.12 CCD25067.1 - 4 7.1 12.7 6.2 6.5 12.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein 2-Hacid_dh_C PF02826.19 CCD25068.1 - 1.2e-33 115.9 0.0 2.3e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CCD25068.1 - 0.036 13.7 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain PEX11 PF05648.14 CCD25069.1 - 9.6e-06 25.2 6.1 2.1e-05 24.1 3.5 2.1 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) DUF3597 PF12200.8 CCD25069.1 - 0.11 13.1 1.3 2.5 8.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Arginase PF00491.21 CCD25070.1 - 8.6e-74 248.5 0.0 1e-73 248.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family GDPD PF03009.17 CCD25071.1 - 2.3e-77 260.2 0.2 1.1e-76 258.1 0.0 2.2 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 CCD25071.1 - 4.8e-36 123.2 8.9 7e-14 52.2 0.1 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CCD25071.1 - 2.4e-19 67.4 1.7 0.0077 16.7 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 CCD25071.1 - 5.3e-19 68.3 0.0 0.0023 18.5 0.0 5.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CCD25071.1 - 1.4e-17 63.5 0.0 0.00021 21.5 0.0 5.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) SPX PF03105.19 CCD25071.1 - 1.6e-11 44.8 10.1 4.8e-07 30.0 3.4 4.2 4 1 1 5 5 5 3 SPX domain Ank PF00023.30 CCD25071.1 - 1.6e-11 44.1 1.4 0.083 13.4 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat ABC1 PF03109.16 CCD25072.1 - 6.7e-19 68.2 0.1 5.8e-18 65.2 0.0 2.4 2 1 0 2 2 2 1 ABC1 family Arf PF00025.21 CCD25073.1 - 9.6e-76 253.1 0.1 1.1e-75 252.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCD25073.1 - 1.5e-15 57.5 0.0 1.9e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CCD25073.1 - 2.8e-11 43.2 0.0 3.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CCD25073.1 - 7.4e-11 41.9 0.0 8.4e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CCD25073.1 - 6.9e-10 38.6 0.3 6.7e-06 25.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CCD25073.1 - 1.3e-09 37.8 0.0 1.6e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCD25073.1 - 0.00013 22.1 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCD25073.1 - 0.0002 20.9 0.1 0.0018 17.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CCD25073.1 - 0.00095 19.7 0.4 0.0036 17.8 0.4 1.7 1 1 0 1 1 1 1 ABC transporter MeaB PF03308.16 CCD25073.1 - 0.0059 15.6 0.6 0.19 10.7 0.2 2.6 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CCD25073.1 - 0.047 14.2 0.1 0.094 13.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 CCD25073.1 - 0.13 11.9 0.8 9 5.8 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Soyouz_module PF14313.6 CCD25074.1 - 0.11 12.3 0.3 0.23 11.3 0.3 1.5 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Oxidored-like PF09791.9 CCD25075.1 - 1.1e-24 85.8 3.5 2.2e-24 84.8 3.5 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal HSP70 PF00012.20 CCD25076.1 - 8.9e-188 625.2 2.9 1.7e-187 624.3 2.9 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCD25076.1 - 5.1e-11 42.0 0.1 2.3e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CCD25076.1 - 0.00088 19.7 0.1 0.022 15.2 0.0 2.8 2 1 0 2 2 2 1 Cell division protein FtsA NLE PF08154.12 CCD25076.1 - 0.049 14.2 0.0 0.21 12.1 0.0 2.1 1 0 0 1 1 1 0 NLE (NUC135) domain Ketoacyl-synt_C PF02801.22 CCD25076.1 - 0.074 13.1 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Trans_reg_C PF00486.28 CCD25076.1 - 0.086 12.9 0.0 0.32 11.1 0.0 1.9 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Endonuc_Holl PF10107.9 CCD25076.1 - 2.3 8.0 5.7 0.48 10.2 0.1 2.6 3 0 0 3 3 3 0 Endonuclease related to archaeal Holliday junction resolvase GYF PF02213.16 CCD25077.1 - 3.2e-14 52.3 0.3 9e-14 50.9 0.3 1.8 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 CCD25077.1 - 0.0049 16.6 0.1 0.014 15.2 0.1 1.9 1 0 0 1 1 1 1 GYF domain 2 tRNA-synt_2 PF00152.20 CCD25078.1 - 3.7e-101 338.3 0.1 5.1e-101 337.9 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCD25078.1 - 1.3e-08 34.7 0.0 2.9e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CCD25078.1 - 0.012 15.1 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Lactamase_B_2 PF12706.7 CCD25079.1 - 2.6e-27 95.7 0.0 4.1e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CCD25079.1 - 4.7e-12 46.1 0.0 8.5e-12 45.3 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain WD40 PF00400.32 CCD25080.1 - 9.3e-05 23.1 0.0 0.024 15.5 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Rad4 PF03835.15 CCD25082.1 - 1.9e-11 43.8 2.4 2.4e-11 43.5 1.0 2.0 2 1 0 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 CCD25082.1 - 4.9e-10 39.9 0.1 9.8e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily zinc-ribbons_6 PF07191.12 CCD25082.1 - 0.41 10.7 4.4 0.42 10.6 2.5 1.9 2 0 0 2 2 2 0 zinc-ribbons IBR PF01485.21 CCD25082.1 - 6.9 7.0 10.9 0.18 12.0 1.4 3.1 3 1 1 4 4 4 0 IBR domain, a half RING-finger domain Sec62 PF03839.16 CCD25083.1 - 3.5e-74 249.0 0.7 3.5e-74 249.0 0.7 1.9 1 1 1 2 2 2 1 Translocation protein Sec62 HlyIII PF03006.20 CCD25083.1 - 0.049 13.3 1.0 0.065 12.9 1.0 1.2 1 0 0 1 1 1 0 Haemolysin-III related MARVEL PF01284.23 CCD25083.1 - 0.19 11.8 3.1 11 6.1 5.1 2.4 2 1 0 2 2 2 0 Membrane-associating domain DUF3309 PF11752.8 CCD25083.1 - 0.2 11.7 8.6 0.56 10.3 8.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3309) DUF1230 PF06799.11 CCD25083.1 - 0.26 11.4 1.5 0.47 10.6 1.5 1.4 1 0 0 1 1 1 0 Conserved in the green lineage and diatoms 27 SLAC1 PF03595.17 CCD25084.1 - 1.1e-81 274.6 34.9 1.3e-81 274.4 34.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF5056 PF16479.5 CCD25084.1 - 1.6 9.0 4.7 1.3 9.4 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) Neurensin PF14927.6 CCD25084.1 - 4.4 7.0 9.8 4.3 7.0 0.1 3.3 3 1 0 3 3 3 0 Neurensin Pyr_redox_2 PF07992.14 CCD25085.1 - 8.2e-63 212.4 0.2 1.4e-62 211.6 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CCD25085.1 - 5e-35 120.1 0.6 5.4e-33 113.6 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CCD25085.1 - 8.2e-20 71.2 0.8 8.2e-20 71.2 0.8 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCD25085.1 - 9.9e-15 54.6 5.5 7.6e-14 51.7 5.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CCD25085.1 - 1.1e-06 28.4 0.1 3.6e-06 26.6 0.0 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CCD25085.1 - 2.6e-06 26.4 4.3 0.41 9.3 0.0 3.9 3 1 1 4 4 4 3 HI0933-like protein K_oxygenase PF13434.6 CCD25085.1 - 2.8e-06 26.7 0.0 5.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 CCD25085.1 - 5.9e-05 22.5 0.3 0.033 13.5 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CCD25085.1 - 0.00013 21.2 1.7 0.049 12.7 1.2 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A 3HCDH_N PF02737.18 CCD25085.1 - 0.0004 20.3 0.1 0.001 19.0 0.1 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CCD25085.1 - 0.029 13.7 1.5 0.29 10.5 0.0 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CCD25085.1 - 0.053 14.0 0.1 14 6.2 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding DNA_pol3_chi PF04364.13 CCD25085.1 - 0.054 13.6 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC ApbA PF02558.16 CCD25085.1 - 0.081 12.6 0.1 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 CCD25085.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.8 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.19 CCD25085.1 - 0.41 9.8 5.6 3.7 6.7 0.2 2.6 2 1 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 CCD25085.1 - 1.8 8.8 4.8 0.3 11.3 0.6 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CCD25085.1 - 2.7 7.5 5.2 7.6 6.0 0.1 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase Ribosomal_S6e PF01092.19 CCD25086.1 - 3.2e-56 188.7 0.2 6.2e-56 187.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e SRF-TF PF00319.18 CCD25087.1 - 1.4e-21 75.7 0.0 2.7e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ceramidase PF05875.12 CCD25088.1 - 8.5e-91 304.0 10.0 9.9e-91 303.8 10.0 1.0 1 0 0 1 1 1 1 Ceramidase Vma12 PF11712.8 CCD25088.1 - 0.092 12.8 2.5 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2660 PF10859.8 CCD25088.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) Sec16_C PF12931.7 CCD25089.1 - 1.9e-77 260.9 0.3 2.7e-77 260.4 0.3 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 CCD25089.1 - 0.00015 22.3 1.0 0.0015 19.1 0.0 3.2 2 1 1 3 3 3 1 Vesicle coat trafficking protein Sec16 mid-region AAA PF00004.29 CCD25090.1 - 8.9e-33 113.5 0.0 1.8e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCD25090.1 - 3.2e-08 33.9 0.0 8.1e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CCD25090.1 - 7.2e-07 29.3 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCD25090.1 - 2.7e-06 27.9 0.3 3.4e-05 24.3 0.1 2.7 2 2 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CCD25090.1 - 4.5e-05 23.4 0.3 0.0013 18.6 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase AAA_18 PF13238.6 CCD25090.1 - 5e-05 23.9 0.1 0.00032 21.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CCD25090.1 - 0.00016 21.5 0.2 0.0004 20.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CCD25090.1 - 0.00017 21.8 0.0 0.00038 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CCD25090.1 - 0.00019 22.0 0.1 0.0006 20.3 0.0 1.9 2 0 0 2 2 1 1 ABC transporter AAA_19 PF13245.6 CCD25090.1 - 0.00024 21.5 0.1 0.00092 19.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain TAN PF11640.8 CCD25090.1 - 0.00026 21.1 0.1 0.00098 19.3 0.1 2.0 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair AAA_30 PF13604.6 CCD25090.1 - 0.00033 20.4 0.0 0.00065 19.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 CCD25090.1 - 0.00044 20.2 0.4 0.0065 16.4 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 CCD25090.1 - 0.00046 20.1 0.2 0.0016 18.4 0.0 2.1 2 1 0 2 2 1 1 NACHT domain RNA_helicase PF00910.22 CCD25090.1 - 0.00065 20.0 0.0 0.0024 18.2 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 CCD25090.1 - 0.00087 19.3 0.1 0.0035 17.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CCD25090.1 - 0.0016 18.2 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CCD25090.1 - 0.0026 17.4 0.2 0.063 12.9 0.0 2.4 1 1 0 2 2 2 1 AAA domain ATPase PF06745.13 CCD25090.1 - 0.0036 16.7 0.8 0.56 9.5 0.0 2.5 1 1 1 2 2 2 1 KaiC TsaE PF02367.17 CCD25090.1 - 0.0038 17.2 0.0 0.0081 16.2 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 CCD25090.1 - 0.0054 16.9 0.1 0.02 15.0 0.0 2.0 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) DUF2075 PF09848.9 CCD25090.1 - 0.0061 15.8 0.1 0.032 13.5 0.0 2.1 2 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 CCD25090.1 - 0.0073 16.7 0.3 0.14 12.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 CCD25090.1 - 0.0078 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 CCD25090.1 - 0.0097 15.8 7.0 0.055 13.4 0.7 3.5 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 CCD25090.1 - 0.011 14.8 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Adeno_IVa2 PF02456.15 CCD25090.1 - 0.013 14.4 0.1 2.7 6.7 0.1 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_23 PF13476.6 CCD25090.1 - 0.013 16.0 0.0 0.013 16.0 0.0 2.9 1 1 1 2 2 1 0 AAA domain ResIII PF04851.15 CCD25090.1 - 0.013 15.5 0.3 0.19 11.8 0.0 2.8 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 CCD25090.1 - 0.019 14.9 0.5 0.057 13.3 0.0 2.0 2 0 0 2 2 2 0 NTPase Viral_helicase1 PF01443.18 CCD25090.1 - 0.021 14.6 0.0 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 CCD25090.1 - 0.021 15.1 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CCD25090.1 - 0.029 13.8 0.1 0.19 11.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein RuvB_N PF05496.12 CCD25090.1 - 0.03 14.1 0.1 0.084 12.6 0.0 1.7 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin PF02224.18 CCD25090.1 - 0.043 13.5 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase PhoH PF02562.16 CCD25090.1 - 0.053 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 CCD25090.1 - 0.053 13.0 0.1 0.18 11.3 0.0 1.9 2 0 0 2 2 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 CCD25090.1 - 0.058 12.7 0.1 0.2 11.0 0.0 1.9 3 0 0 3 3 1 0 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.6 CCD25090.1 - 0.063 13.4 0.0 0.22 11.6 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 CCD25090.1 - 0.067 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 CCD25090.1 - 0.094 12.8 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 1 0 50S ribosome-binding GTPase CopK PF11525.8 CCD25090.1 - 0.14 11.8 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 Copper resistance protein K KTI12 PF08433.10 CCD25090.1 - 0.14 11.6 1.5 0.46 9.9 0.0 2.4 3 0 0 3 3 3 0 Chromatin associated protein KTI12 U3snoRNP10 PF12397.8 CCD25090.1 - 0.15 12.4 0.6 4.5 7.6 0.0 3.0 3 1 0 3 3 2 0 U3 small nucleolar RNA-associated protein 10 AAA_29 PF13555.6 CCD25090.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Endotoxin_N PF03945.14 CCD25090.1 - 0.85 9.3 4.6 0.39 10.4 1.1 2.2 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain DUF3535 PF12054.8 CCD25091.1 - 5.2e-119 398.3 0.4 4.6e-118 395.2 0.4 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 CCD25091.1 - 2.5e-68 230.3 0.0 4.9e-68 229.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCD25091.1 - 5.7e-19 68.5 0.0 2.3e-18 66.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 CCD25091.1 - 4.7e-15 54.4 0.9 0.74 10.2 0.0 8.2 7 0 0 7 7 7 5 HEAT repeat HEAT_EZ PF13513.6 CCD25091.1 - 1.6e-09 38.1 1.3 0.82 10.2 0.0 7.9 8 0 0 8 8 8 1 HEAT-like repeat ResIII PF04851.15 CCD25091.1 - 3.9e-06 27.0 0.0 2.3e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Vac14_Fab1_bd PF12755.7 CCD25091.1 - 8.2e-06 26.3 0.2 4.9 7.8 0.0 5.2 5 0 0 5 5 4 2 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 CCD25091.1 - 1.2e-05 25.5 0.0 6.1 7.2 0.0 5.8 4 1 1 5 5 5 1 TAF6 C-terminal HEAT repeat domain HEAT_2 PF13646.6 CCD25091.1 - 6.3e-05 23.3 0.4 4.6 7.7 0.0 5.1 3 1 0 3 3 3 1 HEAT repeats UME PF08064.13 CCD25091.1 - 0.0054 16.6 3.6 20 5.2 0.0 5.5 5 1 0 5 5 5 0 UME (NUC010) domain GUN4_N PF16416.5 CCD25091.1 - 0.0081 16.1 0.2 0.42 10.6 0.0 2.9 2 0 0 2 2 2 1 ARM-like repeat domain, GUN4-N terminal ERCC3_RAD25_C PF16203.5 CCD25091.1 - 0.021 14.0 0.0 0.05 12.8 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Dna2 PF08696.11 CCD25091.1 - 0.066 13.0 0.1 0.25 11.1 0.1 2.0 1 0 0 1 1 1 0 DNA replication factor Dna2 Pkinase_Tyr PF07714.17 CCD25091.1 - 0.1 11.9 0.1 0.22 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase Sec7_N PF12783.7 CCD25091.1 - 0.92 9.4 6.3 2 8.3 0.5 3.7 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal S4 PF01479.25 CCD25092.1 - 1.6e-13 50.1 0.2 6.3e-13 48.2 0.2 2.0 1 0 0 1 1 1 1 S4 domain Ribosomal_L21e PF01157.18 CCD25093.1 - 7.1e-49 163.8 6.0 2.7e-48 162.0 4.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.9 CCD25093.1 - 0.00027 20.6 0.1 0.00033 20.3 0.1 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Mt_ATP-synt_B PF05405.14 CCD25094.1 - 4.8e-52 175.9 9.2 6e-52 175.6 9.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1940 PF09155.10 CCD25094.1 - 0.086 13.0 1.8 0.22 11.6 1.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1940) DUF5315 PF17242.2 CCD25095.1 - 6.4e-23 80.4 1.9 6.4e-23 80.4 1.9 1.7 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) Orbi_VP3 PF01700.16 CCD25095.1 - 0.074 10.9 0.1 0.089 10.7 0.1 1.2 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein APAF1_C PF17908.1 CCD25095.1 - 0.094 12.7 0.0 4.3 7.3 0.0 2.2 2 0 0 2 2 2 0 APAF-1 helical domain Ntox1 PF15500.6 CCD25095.1 - 0.73 10.2 2.6 3 8.3 1.5 2.6 2 1 0 2 2 2 0 Putative RNase-like toxin, toxin_1 Snapin_Pallidin PF14712.6 CCD25095.1 - 3.1 8.3 6.4 8 7.0 0.8 3.2 2 1 1 3 3 3 0 Snapin/Pallidin GPI2 PF06432.11 CCD25096.1 - 6.8e-64 216.0 19.5 7.7e-64 215.8 19.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase VirB3 PF05101.13 CCD25096.1 - 0.63 10.3 5.1 8.3 6.7 0.9 2.8 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein SPC12 PF06645.13 CCD25096.1 - 5 7.3 8.2 0.89 9.7 3.2 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) GCR1_C PF12550.8 CCD25097.1 - 1.4e-23 83.0 2.2 4.1e-23 81.5 2.2 1.9 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes AAA PF00004.29 CCD25098.1 - 1.3e-40 138.9 0.0 5.5e-40 136.8 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCD25098.1 - 7.1e-08 32.1 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CCD25098.1 - 5.7e-06 26.2 0.0 2.2e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 CCD25098.1 - 1.9e-05 24.9 1.2 0.00012 22.2 0.0 2.9 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CCD25098.1 - 0.00015 21.5 0.0 0.00041 20.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CCD25098.1 - 0.00069 18.9 0.0 0.00069 18.9 0.0 2.9 3 1 0 3 3 2 1 TIP49 P-loop domain AAA_22 PF13401.6 CCD25098.1 - 0.0011 19.3 2.7 0.0014 18.9 0.1 2.6 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CCD25098.1 - 0.0029 17.0 0.1 0.0092 15.4 0.1 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CCD25098.1 - 0.0031 17.9 0.1 0.072 13.5 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CCD25098.1 - 0.0033 17.4 2.0 0.012 15.6 0.0 2.9 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CCD25098.1 - 0.0078 16.0 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 CCD25098.1 - 0.0083 15.6 0.4 0.12 11.9 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_28 PF13521.6 CCD25098.1 - 0.031 14.5 5.0 1.7 8.9 0.1 4.0 3 1 1 4 4 4 0 AAA domain AAA_18 PF13238.6 CCD25098.1 - 0.062 13.9 0.0 0.062 13.9 0.0 3.8 2 2 1 3 3 3 0 AAA domain AAA_25 PF13481.6 CCD25098.1 - 0.11 12.1 0.0 0.49 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CCD25098.1 - 0.36 11.2 0.0 0.36 11.2 0.0 3.3 2 1 0 2 2 1 0 AAA domain ASPRs PF17641.2 CCD25098.1 - 1.2 9.4 9.8 0.14 12.5 4.0 2.2 1 1 1 2 2 2 0 Ancylostoma-associated secreted protein related HI0933_like PF03486.14 CCD25098.1 - 4.3 5.9 8.4 11 4.6 6.8 2.1 2 0 0 2 2 2 0 HI0933-like protein UCH PF00443.29 CCD25099.1 - 2e-32 112.7 8.2 3e-32 112.1 8.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase A2L_zn_ribbon PF08792.10 CCD25099.1 - 0.52 10.1 3.2 16 5.4 0.7 3.0 2 0 0 2 2 2 0 A2L zinc ribbon domain VPS9 PF02204.18 CCD25101.1 - 2.3e-17 63.1 3.1 7.3e-17 61.5 3.1 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Nmad5 PF18757.1 CCD25101.1 - 0.58 10.3 6.1 0.1 12.8 0.5 2.6 2 1 1 3 3 3 0 Nucleotide modification associated domain 5 STATa_Ig PF18214.1 CCD25101.1 - 8.7 6.4 11.6 0.35 10.9 3.0 2.8 3 0 0 3 3 3 0 STATa Immunoglobulin-like domain polyprenyl_synt PF00348.17 CCD25102.1 - 3e-59 200.1 0.0 4e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3605 PF12239.8 CCD25104.1 - 1.3e-36 126.3 5.3 1.6e-36 126.0 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Hyphal_reg_CWP PF11765.8 CCD25104.1 - 0.073 12.0 0.4 0.099 11.6 0.4 1.2 1 0 0 1 1 1 0 Hyphally regulated cell wall protein N-terminal CorA PF01544.18 CCD25105.1 - 7.7e-05 22.1 9.3 0.00011 21.7 9.3 1.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PhetRS_B1 PF18262.1 CCD25105.1 - 0.042 14.1 0.4 0.19 12.0 0.3 2.2 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain Glutaredoxin PF00462.24 CCD25106.1 - 1.9e-18 66.4 0.0 3.2e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Aldedh PF00171.22 CCD25107.1 - 1.7e-172 574.1 0.2 1.9e-172 573.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GramPos_pilinBB PF16569.5 CCD25107.1 - 0.032 15.1 0.1 0.2 12.5 0.1 2.3 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 2, Cna-B-like domain NIF PF03031.18 CCD25108.1 - 8.6e-44 149.0 0.1 1.4e-43 148.4 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pro_isomerase PF00160.21 CCD25109.1 - 0.00012 22.4 0.0 0.00067 20.0 0.0 2.1 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD VPS28 PF03997.12 CCD25110.1 - 8.9e-75 250.5 4.9 1.1e-74 250.2 4.9 1.1 1 0 0 1 1 1 1 VPS28 protein DUF4363 PF14276.6 CCD25110.1 - 0.012 15.7 0.7 0.16 12.1 0.1 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4363) DUF4179 PF13786.6 CCD25111.1 - 0.016 15.6 1.8 0.046 14.2 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) ABC2_membrane PF01061.24 CCD25112.1 - 5.1e-64 215.5 46.7 1.2e-33 116.3 19.2 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 CCD25112.1 - 5.4e-36 124.1 0.0 1.2e-17 64.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CCD25112.1 - 5.6e-33 112.7 5.2 1.1e-28 98.9 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CCD25112.1 - 8.1e-08 32.8 0.0 1.7e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 CCD25112.1 - 1.7e-07 31.3 0.1 5.6e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 CCD25112.1 - 5.5e-07 29.0 2.5 5.5e-07 29.0 2.5 3.5 3 1 0 3 3 2 1 ABC-2 family transporter protein AAA_16 PF13191.6 CCD25112.1 - 1.1e-05 25.8 0.1 0.0044 17.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 CCD25112.1 - 0.0003 20.8 0.1 0.63 10.1 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.12 CCD25112.1 - 0.00035 19.9 0.1 0.78 9.0 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 CCD25112.1 - 0.00047 20.5 0.4 0.083 13.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 CCD25112.1 - 0.00056 19.4 0.0 2.8 7.3 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCD25112.1 - 0.00067 19.3 0.3 0.098 12.4 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CCD25112.1 - 0.00097 19.7 0.0 0.04 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CCD25112.1 - 0.0024 17.8 0.0 0.085 12.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 CCD25112.1 - 0.0025 17.4 0.4 0.06 12.9 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CCD25112.1 - 0.005 17.0 0.0 0.44 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CCD25112.1 - 0.0063 16.9 0.0 2.1 8.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_21 PF13304.6 CCD25112.1 - 0.0066 16.3 0.0 4.3 7.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 CCD25112.1 - 0.0089 15.8 1.2 0.87 9.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CCD25112.1 - 0.017 14.7 0.1 0.28 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CCD25112.1 - 0.024 14.5 0.2 14 5.5 0.1 3.2 3 0 0 3 3 3 0 NTPase AAA_17 PF13207.6 CCD25112.1 - 0.037 14.5 0.1 0.56 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 CCD25112.1 - 0.045 13.7 0.1 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TsaE PF02367.17 CCD25112.1 - 0.069 13.1 1.0 0.2 11.7 0.1 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CCD25112.1 - 0.096 12.4 0.2 2.2 8.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CCD25112.1 - 0.32 11.5 1.3 0.51 10.8 0.1 1.9 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.22 CCD25112.1 - 0.41 9.8 1.1 11 5.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Gly_transf_sug PF04488.15 CCD25113.1 - 3.2e-23 82.2 0.0 9.8e-23 80.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF4752 PF15944.5 CCD25113.1 - 1.9 8.6 4.7 1.8 8.7 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4752) Lge1 PF11488.8 CCD25114.1 - 1.9e-18 66.4 9.4 4.8e-18 65.1 9.4 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 PRIMA1 PF16101.5 CCD25114.1 - 0.017 15.1 4.3 0.036 14.1 4.3 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf_CCCH_4 PF18345.1 CCD25115.1 - 9.8e-10 38.2 21.5 3.9e-05 23.6 5.5 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CCD25115.1 - 4.1e-09 36.1 12.9 2.6e-05 24.0 2.5 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CCD25115.1 - 3.7e-08 33.0 14.4 0.00023 20.9 4.8 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CCD25115.1 - 0.00075 19.7 2.8 0.00075 19.7 2.8 2.0 2 0 0 2 2 2 1 Zinc-finger containing family Torus PF16131.5 CCD25115.1 - 0.00078 20.1 0.6 0.00078 20.1 0.6 4.1 4 1 1 5 5 5 2 Torus domain zf-CCCH_2 PF14608.6 CCD25115.1 - 0.55 10.8 23.3 0.11 13.1 6.9 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Glyco_transf_15 PF01793.16 CCD25116.1 - 5.7e-100 334.7 16.2 8.5e-100 334.1 16.2 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CCDC92 PF14916.6 CCD25116.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function ODC_AZ PF02100.17 CCD25117.1 - 1.8e-05 24.7 0.0 3.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Arf PF00025.21 CCD25118.1 - 2.1e-46 157.6 0.2 2.6e-46 157.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CCD25118.1 - 4.2e-15 55.7 0.0 5.6e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD25118.1 - 4.2e-13 49.6 0.0 7e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CCD25118.1 - 2e-12 47.0 1.7 1.1e-09 37.9 0.7 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CCD25118.1 - 2.5e-12 46.6 0.9 1e-11 44.6 0.4 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CCD25118.1 - 1.1e-07 31.5 0.1 1.2e-06 28.2 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CCD25118.1 - 1.2e-07 31.4 0.4 1.3e-07 31.2 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCD25118.1 - 1.3e-06 28.4 0.0 2.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CCD25118.1 - 0.0025 18.1 0.0 0.011 15.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain TniB PF05621.11 CCD25118.1 - 0.026 14.0 0.0 0.066 12.6 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein MeaB PF03308.16 CCD25118.1 - 0.032 13.2 0.1 0.061 12.3 0.2 1.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CoA_binding PF02629.19 CCD25118.1 - 0.13 12.9 0.0 0.3 11.8 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain Anp1 PF03452.14 CCD25119.1 - 2.2e-106 355.1 0.3 2.8e-106 354.8 0.3 1.1 1 0 0 1 1 1 1 Anp1 Glyco_transf_8 PF01501.20 CCD25119.1 - 0.0043 16.7 0.2 0.0098 15.5 0.2 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glycos_transf_2 PF00535.26 CCD25119.1 - 0.0059 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF4286 PF14114.6 CCD25119.1 - 0.0066 16.9 0.4 0.022 15.2 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) EF1G PF00647.19 CCD25120.1 - 4.3e-47 158.6 0.1 7.8e-47 157.8 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 CCD25120.1 - 1.1e-14 54.5 0.0 3.3e-14 53.0 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CCD25120.1 - 1.7e-13 50.6 0.4 3.6e-13 49.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCD25120.1 - 0.00014 21.8 0.0 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CCD25120.1 - 0.00033 21.0 0.0 0.0008 19.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CCD25120.1 - 0.0012 19.0 0.0 0.0032 17.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sgf11_N PF18519.1 CCD25121.1 - 1.5e-21 75.7 0.1 2.1e-21 75.2 0.1 1.2 1 0 0 1 1 1 1 SAGA-associated factor 11 N-terminal domain Sgf11 PF08209.11 CCD25121.1 - 2.8e-16 58.7 4.4 6.1e-16 57.7 4.4 1.5 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-CpG_bind_C PF12269.8 CCD25121.1 - 0.0043 16.9 0.0 0.0043 16.9 0.0 1.1 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain zf_C2H2_13 PF18508.1 CCD25121.1 - 0.082 12.5 0.3 0.17 11.5 0.1 1.7 2 0 0 2 2 2 0 Zinc finger domain DUF1451 PF07295.11 CCD25121.1 - 0.093 12.8 0.2 0.77 9.8 0.2 1.9 1 1 0 1 1 1 0 Zinc-ribbon containing domain Skp1_POZ PF03931.15 CCD25122.1 - 2.6e-10 40.3 0.0 4.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Vps16_C PF04840.12 CCD25123.1 - 5.7e-83 278.6 11.1 1.8e-82 276.9 8.5 2.1 2 0 0 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.13 CCD25123.1 - 4.7e-58 196.9 0.5 5.8e-47 160.3 0.0 2.3 2 0 0 2 2 2 2 Vps16, N-terminal region RRM_1 PF00076.22 CCD25124.1 - 2.5e-53 177.8 0.1 5.2e-17 61.4 0.1 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD25124.1 - 4e-09 36.5 0.0 0.026 14.7 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif PHM7_cyt PF14703.6 CCD25124.1 - 7.3e-06 26.3 6.6 0.12 12.7 0.1 5.8 5 3 3 8 8 8 3 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 CCD25124.1 - 0.0069 16.2 0.0 3.8 7.3 0.0 2.8 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain TRAP_alpha PF03896.16 CCD25124.1 - 0.81 8.8 11.6 0.12 11.5 3.4 2.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Pkinase PF00069.25 CCD25125.1 - 3.1e-55 187.4 2.2 4.3e-54 183.7 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25125.1 - 7.2e-25 87.7 5.0 8.5e-25 87.5 0.2 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase FLILHELTA PF10306.9 CCD25126.1 - 1.4e-22 79.9 0.0 2.7e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA tRNA-synt_1 PF00133.22 CCD25127.1 - 1.6e-162 541.9 0.2 2.3e-162 541.4 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CCD25127.1 - 2.5e-23 82.5 0.3 1.9e-12 46.6 0.0 3.5 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CCD25127.1 - 1.1e-19 70.9 0.9 1.1e-19 70.9 0.9 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 CCD25127.1 - 0.0042 16.6 0.1 0.045 13.3 0.0 2.3 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 CCD25127.1 - 0.032 13.6 0.0 5.8 6.2 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DZR PF12773.7 CCD25127.1 - 1.3 9.1 3.6 2.6 8.2 3.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_4 PF13894.6 CCD25129.1 - 5.3e-09 36.2 3.1 0.0011 19.7 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CCD25129.1 - 4.4e-07 30.0 4.2 0.0023 18.3 0.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CCD25129.1 - 0.0026 17.7 2.5 0.64 10.1 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CCD25129.1 - 0.012 16.2 3.7 0.056 14.1 0.6 2.7 2 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 CCD25129.1 - 0.052 13.9 0.4 0.42 11.0 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 CCD25129.1 - 0.061 13.1 2.1 0.49 10.2 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_UBZ PF18439.1 CCD25129.1 - 0.13 11.8 1.4 8.2 6.1 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger PSCyt3 PF07627.11 CCD25129.1 - 0.61 10.4 3.6 0.28 11.5 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) NAC PF01849.18 CCD25130.1 - 1.4e-15 57.0 0.1 3.3e-15 55.8 0.1 1.7 1 0 0 1 1 1 1 NAC domain zf-CCHC PF00098.23 CCD25131.1 - 0.00014 21.8 2.0 0.00023 21.1 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 CCD25131.1 - 0.12 12.1 1.3 0.28 10.9 1.3 1.6 1 0 0 1 1 1 0 Zinc knuckle ApbA_C PF08546.11 CCD25133.1 - 9.8e-08 32.2 0.0 2.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pkinase PF00069.25 CCD25134.1 - 2.8e-75 253.1 0.0 3.4e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25134.1 - 1.2e-37 129.6 0.0 1.7e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCD25134.1 - 0.002 17.1 0.0 0.0085 15.1 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CCD25134.1 - 0.0021 17.4 0.0 0.0037 16.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CCD25134.1 - 0.049 13.5 0.0 0.29 11.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family AdoMet_MTase PF07757.13 CCD25135.1 - 9.6e-39 132.2 1.3 1.3e-37 128.6 1.3 2.3 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 CCD25135.1 - 0.00078 19.3 0.2 0.0058 16.4 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 CCD25135.1 - 0.088 12.8 0.4 5.7 6.9 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain SUV3_C PF12513.8 CCD25136.1 - 2.3e-17 62.6 1.3 5.2e-17 61.5 1.3 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 CCD25136.1 - 1.3e-12 48.1 0.6 5.8e-12 45.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCD25136.1 - 0.0026 17.6 0.0 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase RNA_pol_A_bac PF01000.26 CCD25136.1 - 0.069 13.5 0.4 0.6 10.5 0.1 2.6 2 1 0 2 2 2 0 RNA polymerase Rpb3/RpoA insert domain Thiolase_N PF00108.23 CCD25137.1 - 1.1e-92 310.0 1.8 1.4e-92 309.8 1.8 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CCD25137.1 - 1.5e-46 157.1 2.5 2.1e-46 156.6 0.1 2.4 3 1 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CCD25137.1 - 2.8e-06 27.1 1.1 5.8e-06 26.1 1.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Pkinase PF00069.25 CCD25138.1 - 1.4e-47 162.3 5.4 6.5e-41 140.4 1.7 2.8 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25138.1 - 7.6e-23 81.1 0.3 1.4e-18 67.1 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCD25138.1 - 1.4e-05 24.6 0.1 0.0001 21.7 0.1 2.2 1 1 0 1 1 1 1 Kinase-like Smg4_UPF3 PF03467.15 CCD25138.1 - 0.015 15.3 0.2 0.027 14.5 0.2 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family DUF4183 PF13799.6 CCD25138.1 - 0.06 13.2 1.9 0.16 11.8 1.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4183) RMI1_N PF08585.12 CCD25139.1 - 1.9e-16 60.5 0.0 2.9e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 RecQ mediated genome instability protein Spo7_2_N PF15407.6 CCD25139.1 - 0.14 11.8 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Sporulation protein family 7 MTHFR PF02219.17 CCD25140.1 - 3e-108 361.5 0.0 3.9e-108 361.1 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ERCC4 PF02732.15 CCD25141.1 - 8.6e-22 78.0 0.0 2.3e-21 76.6 0.0 1.8 1 0 0 1 1 1 1 ERCC4 domain HHH_2 PF12826.7 CCD25141.1 - 0.1 12.7 0.2 6.5 6.9 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif ARID PF01388.21 CCD25142.1 - 3e-17 63.1 0.3 3e-17 63.1 0.3 3.6 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain Torus PF16131.5 CCD25143.1 - 1.9e-34 118.6 1.0 2.9e-34 118.0 0.1 1.7 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 CCD25143.1 - 9.4e-05 22.2 0.1 0.00024 20.9 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 CCD25143.1 - 0.013 15.3 4.1 0.013 15.3 4.1 2.0 1 1 1 2 2 2 0 CCCH-type zinc finger PAP_RNA-bind PF04926.15 CCD25143.1 - 0.024 14.3 0.0 0.048 13.3 0.0 1.5 1 1 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain zf_CCCH_4 PF18345.1 CCD25143.1 - 0.15 12.1 5.3 0.4 10.8 5.3 1.8 1 0 0 1 1 1 0 Zinc finger domain GLE1 PF07817.13 CCD25144.1 - 1.6e-88 296.1 1.2 3.3e-88 295.2 1.2 1.5 1 0 0 1 1 1 1 GLE1-like protein SOBP PF15279.6 CCD25144.1 - 2.2 8.8 5.9 3.6 8.1 5.9 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein DUF572 PF04502.13 CCD25144.1 - 3.8 7.0 34.6 6.2 6.3 34.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) eIF3_subunit PF08597.10 CCD25144.1 - 9.7 6.0 52.6 0.094 12.6 26.2 2.6 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit Na_Ca_ex PF01699.24 CCD25145.1 - 9.9e-51 171.7 37.8 6.3e-28 97.6 6.0 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Porphobil_deam PF01379.20 CCD25146.1 - 6.4e-73 244.6 0.0 7.9e-73 244.3 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CCD25146.1 - 9.8e-21 73.9 0.3 1.8e-20 73.0 0.3 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Reticulon PF02453.17 CCD25147.1 - 2.5e-24 86.0 10.3 3.6e-24 85.5 10.3 1.2 1 0 0 1 1 1 1 Reticulon DUF639 PF04842.12 CCD25147.1 - 0.00019 20.9 3.4 0.00026 20.5 3.4 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) TDA11 PF17084.5 CCD25147.1 - 0.14 11.1 0.1 0.29 10.0 0.0 1.5 2 0 0 2 2 2 0 Topoisomerase I damage affected protein 11 Sel1 PF08238.12 CCD25148.1 - 1.8e-21 76.1 18.6 4.3e-07 30.4 0.0 7.5 6 2 1 7 7 7 6 Sel1 repeat Ribosomal_L10 PF00466.20 CCD25149.1 - 7.6e-07 29.2 0.0 1.8e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Methyltransf_4 PF02390.17 CCD25150.1 - 1.5e-59 200.4 0.1 2.1e-59 199.9 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 CCD25150.1 - 0.00061 20.4 0.0 0.0015 19.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCD25150.1 - 0.0021 18.8 0.0 0.0064 17.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCD25150.1 - 0.0071 16.1 0.0 0.012 15.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DUF844 PF05815.11 CCD25150.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Ubie_methyltran PF01209.18 CCD25150.1 - 0.095 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 CCD25150.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain DNA_binding_1 PF01035.20 CCD25151.1 - 7.1e-28 96.6 0.0 1e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 CCD25151.1 - 0.042 14.7 0.1 0.065 14.0 0.1 1.3 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain LSM PF01423.22 CCD25153.1 - 8e-18 63.9 0.1 9.1e-18 63.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.17 CCD25153.1 - 0.042 13.7 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Rhabdo_ncap PF00945.18 CCD25153.1 - 0.18 10.7 0.3 0.21 10.4 0.3 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Cohesin_load PF10345.9 CCD25154.1 - 4.8e-83 279.6 35.3 5.8e-83 279.3 35.3 1.0 1 0 0 1 1 1 1 Cohesin loading factor DUF1376 PF07120.11 CCD25154.1 - 0.067 13.5 0.0 0.2 12.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) TBP PF00352.21 CCD25155.1 - 3.4e-68 225.6 0.1 8.1e-33 112.2 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CCD25155.1 - 0.00014 21.9 3.2 0.26 11.4 0.0 3.1 3 1 1 4 4 4 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 CCD25155.1 - 0.044 13.6 0.2 0.3 10.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) MDFI PF15316.6 CCD25155.1 - 0.23 11.6 0.3 0.34 11.0 0.3 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Mito_carr PF00153.27 CCD25156.1 - 1.5e-31 108.2 0.2 1.8e-14 53.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein WYL_3 PF18488.1 CCD25159.1 - 0.49 10.8 5.5 4.9 7.6 0.8 3.8 4 0 0 4 4 4 0 WYL domain Rsa3 PF14615.6 CCD25160.1 - 4.2e-19 67.8 0.2 8e-19 66.9 0.2 1.5 1 0 0 1 1 1 1 Ribosome-assembly protein 3 IMUP PF15761.5 CCD25160.1 - 0.032 14.9 4.7 0.082 13.6 4.7 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CCD25160.1 - 0.81 9.2 16.1 0.88 9.1 15.6 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 CCD25160.1 - 6.8 7.0 16.5 17 5.7 16.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Utp13 PF08625.11 CCD25161.1 - 8.1e-50 168.4 1.3 1.6e-49 167.5 1.3 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 CCD25161.1 - 7.8e-48 159.5 28.5 6.1e-07 30.0 0.2 10.8 10 0 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD25161.1 - 1.2e-17 64.0 7.7 0.0034 17.7 0.1 7.5 6 2 2 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCD25161.1 - 9.4e-08 31.7 8.9 0.029 13.7 0.1 3.8 3 1 1 4 4 4 3 WD40-like domain Ge1_WD40 PF16529.5 CCD25161.1 - 0.00026 20.1 15.4 0.0022 17.0 0.2 5.4 4 1 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CCD25161.1 - 0.0083 15.5 0.1 2.6 7.3 0.0 3.0 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 CCD25161.1 - 0.059 13.2 1.3 24 4.7 0.0 3.7 3 2 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A DUF4800 PF16057.5 CCD25161.1 - 0.072 12.4 0.4 0.56 9.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4800) PIP5K PF01504.18 CCD25162.1 - 1.8e-81 273.4 6.0 1.8e-81 273.4 6.0 2.4 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Di19_C PF14571.6 CCD25162.1 - 0.16 12.5 16.3 0.31 11.6 8.1 2.7 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal SOBP PF15279.6 CCD25162.1 - 1.8 9.1 19.4 2.8 8.4 19.4 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Pex14_N PF04695.13 CCD25162.1 - 2.9 8.5 13.9 0.65 10.6 2.0 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zn_clus PF00172.18 CCD25163.1 - 2.4e-09 37.1 12.2 3.9e-09 36.5 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 CCD25163.1 - 5.5 7.1 24.9 1.4 9.0 6.5 3.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CRF1 PF10380.9 CCD25166.1 - 1.3e-35 122.2 6.0 1.3e-35 122.2 6.0 4.6 4 2 0 4 4 4 1 Transcription factor CRF1 Lum_binding PF00677.17 CCD25167.1 - 1.5e-41 140.3 3.3 2.9e-20 72.1 0.3 2.2 2 0 0 2 2 2 2 Lumazine binding domain Cut8 PF08559.10 CCD25168.1 - 1.5e-69 234.3 14.4 2e-69 233.9 14.4 1.2 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Sedlin_N PF04628.13 CCD25171.1 - 3.1e-48 163.2 0.0 5.1e-48 162.5 0.0 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CCD25171.1 - 4.4e-05 23.4 0.5 0.006 16.5 0.1 2.5 3 0 0 3 3 3 2 Sybindin-like family Med22 PF06179.12 CCD25172.1 - 1.6e-23 82.9 4.3 3.3e-23 81.9 4.3 1.5 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF2400 PF09674.10 CCD25172.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Ribosomal_S5_C PF03719.15 CCD25173.1 - 4.1e-24 83.8 0.0 8.3e-24 82.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CCD25173.1 - 6.2e-22 77.4 0.2 9.9e-22 76.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain HMG_box PF00505.19 CCD25174.1 - 2.1e-13 50.5 12.7 6.1e-13 49.0 10.1 2.7 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCD25174.1 - 0.00064 20.3 4.7 0.0018 18.9 4.7 1.7 1 1 0 1 1 1 1 HMG-box domain CBP_BcsQ PF06564.12 CCD25174.1 - 0.025 14.0 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Peptidase_M41 PF01434.18 CCD25175.1 - 1.4e-68 230.5 0.0 1.4e-68 230.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 CCD25175.1 - 8.7e-44 149.1 0.0 2.3e-43 147.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCD25175.1 - 3.6e-13 49.1 0.0 1.1e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 CCD25175.1 - 1.4e-06 28.6 0.5 1.4e-06 28.6 0.5 2.3 3 0 0 3 3 2 1 FtsH Extracellular AAA_5 PF07728.14 CCD25175.1 - 0.00039 20.4 0.0 0.0022 18.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CCD25175.1 - 0.0043 16.3 1.0 0.0097 15.1 0.1 2.0 2 1 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 CCD25175.1 - 0.0051 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCD25175.1 - 0.0076 16.5 0.9 0.7 10.2 0.1 3.0 4 0 0 4 4 2 1 AAA domain IstB_IS21 PF01695.17 CCD25175.1 - 0.013 15.3 0.0 0.049 13.4 0.0 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 CCD25175.1 - 0.038 14.1 2.1 0.14 12.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 CCD25175.1 - 0.044 14.2 0.0 0.044 14.2 0.0 2.3 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 CCD25175.1 - 0.17 12.1 0.0 0.57 10.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 CCD25175.1 - 2.1 7.4 6.9 2.2 7.3 4.0 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein IMD PF08397.11 CCD25175.1 - 3.1 7.1 8.2 2.3 7.5 0.5 2.7 2 1 0 2 2 2 0 IRSp53/MIM homology domain AAA_18 PF13238.6 CCD25175.1 - 6.2 7.4 6.2 3.2 8.3 0.0 3.3 3 1 0 3 3 3 0 AAA domain EB1 PF03271.17 CCD25176.1 - 3.6e-15 55.9 0.7 3.6e-15 55.9 0.7 1.9 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 CCD25176.1 - 2.7e-05 24.3 0.5 5.9e-05 23.2 0.5 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain zf-C4H2 PF10146.9 CCD25176.1 - 0.0046 17.3 3.8 0.0046 17.3 3.8 1.6 2 0 0 2 2 2 1 Zinc finger-containing protein ATG16 PF08614.11 CCD25176.1 - 0.035 14.3 0.1 0.065 13.5 0.1 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 CCD25176.1 - 0.039 13.7 0.3 0.09 12.6 0.3 1.6 1 0 0 1 1 1 0 Septum formation initiator BST2 PF16716.5 CCD25176.1 - 0.053 14.1 0.7 0.12 13.0 0.6 1.6 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 CENP-Q PF13094.6 CCD25176.1 - 0.088 13.0 0.5 0.15 12.3 0.5 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HrpB7 PF09486.10 CCD25176.1 - 0.099 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) TolA_bind_tri PF16331.5 CCD25176.1 - 0.17 12.0 2.3 0.73 10.0 0.3 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation AMP-binding PF00501.28 CCD25177.1 - 3e-74 250.1 0.0 4e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Amino_oxidase PF01593.24 CCD25178.1 - 1.7e-13 50.7 0.0 2.1e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CCD25178.1 - 6.2e-11 42.4 0.0 1.6e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CCD25178.1 - 4.9e-05 23.8 1.7 0.0077 16.8 0.1 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CCD25178.1 - 0.0098 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CCD25178.1 - 0.01 15.1 0.1 0.23 10.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CCD25178.1 - 0.017 15.1 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 CCD25178.1 - 0.02 14.2 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HA2 PF04408.23 CCD25179.1 - 1.5e-22 79.9 0.0 5e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CCD25179.1 - 4.3e-18 65.5 0.0 9e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.23 CCD25179.1 - 1.2e-14 54.4 0.4 2.9e-14 53.1 0.4 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.31 CCD25179.1 - 4.5e-13 49.5 0.0 1.5e-12 47.8 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCD25179.1 - 1.4e-06 28.2 0.2 3.3e-06 27.0 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCD25179.1 - 3.2e-06 27.4 0.1 8.7e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCD25179.1 - 8e-05 22.4 0.1 0.00015 21.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CCD25179.1 - 0.00085 19.9 6.0 0.23 11.9 0.1 3.8 2 2 1 3 3 3 2 ABC transporter T2SSE PF00437.20 CCD25179.1 - 0.0027 16.8 0.0 0.0098 15.0 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.6 CCD25179.1 - 0.0094 16.0 0.2 0.15 12.1 0.2 2.6 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 CCD25179.1 - 0.011 15.4 0.1 0.027 14.1 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CCD25179.1 - 0.011 16.0 0.1 0.024 15.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CCD25179.1 - 0.037 13.5 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 CCD25179.1 - 0.045 13.9 0.0 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.6 CCD25179.1 - 0.051 14.1 4.0 0.74 10.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CCD25179.1 - 0.11 11.9 0.0 0.31 10.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Proteasome PF00227.26 CCD25180.1 - 1.1e-43 148.9 0.0 1.3e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit NAD_binding_10 PF13460.6 CCD25181.1 - 2.2e-07 31.0 0.0 3.5e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 CCD25181.1 - 2.3e-07 30.5 0.0 1.3e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 HIM1 Epimerase PF01370.21 CCD25181.1 - 7.6e-05 22.3 0.0 0.00012 21.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CCD25181.1 - 0.0017 18.0 0.1 0.0078 15.8 0.1 2.2 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 CCD25181.1 - 0.026 13.7 0.0 0.56 9.3 0.0 2.2 1 1 1 2 2 2 0 Male sterility protein Semialdhyde_dh PF01118.24 CCD25181.1 - 0.065 13.7 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SRP1_TIP1 PF00660.17 CCD25182.1 - 4.5e-28 97.2 0.5 4.5e-28 97.2 0.5 2.3 2 0 0 2 2 2 1 Seripauperin and TIP1 family XRN_M PF17846.1 CCD25182.1 - 0.36 9.7 0.0 0.36 9.7 0.0 2.0 2 0 0 2 2 2 0 Xrn1 helical domain WSC PF01822.19 CCD25183.1 - 4.9e-11 42.7 15.4 4.9e-11 42.7 15.4 2.3 2 0 0 2 2 2 1 WSC domain Amnionless PF14828.6 CCD25183.1 - 0.00019 20.4 1.1 0.00019 20.4 1.1 1.4 2 0 0 2 2 2 1 Amnionless Gly-zipper_Omp PF13488.6 CCD25183.1 - 0.0015 18.4 1.4 0.003 17.5 1.4 1.5 1 0 0 1 1 1 1 Glycine zipper ApbA_C PF08546.11 CCD25183.1 - 0.021 15.0 0.0 0.036 14.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Bacteriocin_IIc PF10439.9 CCD25183.1 - 0.032 14.3 1.1 0.032 14.3 1.1 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Romo1 PF10247.9 CCD25183.1 - 0.22 11.9 2.2 0.5 10.8 2.2 1.6 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Hamartin PF04388.12 CCD25183.1 - 3.2 6.3 12.6 3.8 6.0 12.6 1.1 1 0 0 1 1 1 0 Hamartin protein DUF2408 PF10303.9 CCD25184.1 - 3.2e-60 202.6 26.6 1.7e-43 148.4 3.9 5.1 2 2 3 5 5 5 4 Protein of unknown function (DUF2408) Exonuc_VII_L PF02601.15 CCD25184.1 - 0.021 14.4 5.1 0.014 15.0 3.1 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit FAA_hydro_N_2 PF18288.1 CCD25184.1 - 0.038 14.4 1.3 6 7.4 0.1 3.7 4 0 0 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 MtrG PF04210.13 CCD25184.1 - 0.3 11.0 1.1 23 5.0 0.0 3.1 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G MLD PF11647.8 CCD25184.1 - 0.94 9.8 8.1 0.62 10.4 0.4 3.9 3 2 0 3 3 3 0 Membrane Localization Domain Adap_comp_sub PF00928.21 CCD25185.1 - 4e-93 311.6 3.9 5.4e-93 311.2 3.9 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 CCD25185.1 - 4.9e-05 22.9 0.1 9.3e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Clat_adaptor_s PF01217.20 CCD25185.1 - 0.00025 21.0 0.8 0.00047 20.1 0.8 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4442 PF14539.6 CCD25185.1 - 0.16 12.1 0.1 2.7 8.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4442) TPP1 PF10341.9 CCD25186.1 - 8e-32 109.5 0.2 1.1e-31 109.1 0.2 1.2 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD DUF5505 PF17610.2 CCD25186.1 - 0.051 13.6 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5505) ETF_QO PF05187.13 CCD25187.1 - 8.7e-43 144.7 1.4 1.5e-42 143.9 1.4 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 CCD25187.1 - 2e-10 40.8 0.0 5.8e-06 26.1 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 CCD25187.1 - 4.1e-08 32.8 0.0 2.2e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 CCD25187.1 - 4.5e-08 33.2 0.0 1.3e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CCD25187.1 - 2.5e-07 30.1 0.1 0.0016 17.6 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 CCD25187.1 - 5.7e-05 22.5 0.0 0.0012 18.1 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CCD25187.1 - 9.5e-05 21.3 0.0 0.00062 18.6 0.0 2.0 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 CCD25187.1 - 0.00036 19.9 0.1 0.00073 18.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CCD25187.1 - 0.00037 19.8 0.0 0.00055 19.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 CCD25187.1 - 0.00074 19.5 0.0 0.0013 18.7 0.0 1.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 CCD25187.1 - 0.0014 18.1 0.0 0.0027 17.1 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CCD25187.1 - 0.0017 18.9 0.1 1.4 9.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CCD25187.1 - 0.0026 16.7 0.2 0.025 13.4 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GMC_oxred_N PF00732.19 CCD25187.1 - 0.005 16.3 0.0 0.38 10.1 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CCD25187.1 - 0.025 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_7 PF12838.7 CCD25187.1 - 0.04 14.5 0.6 0.096 13.3 0.6 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 CCD25187.1 - 0.087 13.0 0.5 0.25 11.5 0.5 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_10 PF13237.6 CCD25187.1 - 0.089 12.9 0.6 0.19 11.8 0.6 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF2877 PF11392.8 CCD25188.1 - 0.5 11.1 1.8 2.7 8.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) Cyclin_N PF00134.23 CCD25189.1 - 4e-28 97.7 2.2 9.4e-28 96.5 2.2 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain DAG_kinase_N PF14513.6 CCD25190.1 - 0.031 14.5 0.5 0.031 14.5 0.5 2.5 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Pox_D2 PF04701.13 CCD25190.1 - 0.033 14.4 2.5 0.35 11.0 0.1 2.9 2 0 0 2 2 2 0 Pox virus D2 protein SOG2 PF10428.9 CCD25191.1 - 2e-159 532.1 44.8 2e-159 532.1 44.8 4.1 3 1 0 3 3 3 1 RAM signalling pathway protein LRR_8 PF13855.6 CCD25191.1 - 7.6e-13 48.0 12.1 1.3e-07 31.3 1.5 3.1 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CCD25191.1 - 1.6e-11 44.2 18.0 1.9e-06 28.1 1.8 4.7 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) PRD PF00874.20 CCD25191.1 - 0.011 16.0 0.8 0.039 14.2 0.8 2.0 1 0 0 1 1 1 0 PRD domain LRR_6 PF13516.6 CCD25191.1 - 0.012 15.6 6.8 25 5.2 0.4 5.8 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 CCD25191.1 - 0.13 12.9 10.1 4.8 8.1 0.8 5.8 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_9 PF14580.6 CCD25191.1 - 0.13 11.7 10.0 0.13 11.7 0.4 3.0 2 1 1 3 3 3 0 Leucine-rich repeat TFB6 PF17110.5 CCD25192.1 - 1.5e-38 132.2 0.0 8.2e-34 116.8 0.0 2.3 1 1 1 2 2 2 2 Subunit 11 of the general transcription factor TFIIH Pkinase PF00069.25 CCD25193.1 - 2.9e-53 180.9 0.7 5.4e-36 124.3 0.1 2.9 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25193.1 - 1.3e-28 100.0 0.0 8.7e-24 84.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 CCD25193.1 - 1.4e-15 57.3 0.0 5.2e-15 55.5 0.0 2.1 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 CCD25193.1 - 1.1e-07 31.0 0.1 2.9e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CCD25193.1 - 1.8e-05 24.2 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Yop-YscD_cpl PF16697.5 CCD25193.1 - 0.00076 19.7 0.0 0.0088 16.3 0.0 2.3 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 CCD25193.1 - 0.0064 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MNE1 PF13762.6 CCD25195.1 - 1.2e-16 61.0 6.6 1.2e-16 61.0 6.6 4.4 3 2 2 5 5 5 1 Mitochondrial splicing apparatus component TFCD_C PF12612.8 CCD25196.1 - 0.0017 18.2 0.4 0.0082 16.0 0.0 2.4 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal Mistic PF11458.8 CCD25196.1 - 0.0034 17.3 1.7 0.013 15.4 0.2 2.7 2 0 0 2 2 2 1 Membrane-integrating protein Mistic ANAPC5 PF12862.7 CCD25196.1 - 0.17 12.0 6.6 4.1 7.5 0.2 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 AA_permease PF00324.21 CCD25197.1 - 1.3e-131 439.5 38.1 1.5e-131 439.3 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD25197.1 - 4.1e-20 72.0 41.6 5.5e-20 71.6 41.6 1.0 1 0 0 1 1 1 1 Amino acid permease DNApol_Exo PF18136.1 CCD25198.1 - 6.6e-103 343.7 0.1 1.2e-102 342.8 0.1 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 CCD25198.1 - 3.5e-54 184.3 0.0 7e-54 183.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family A CorA PF01544.18 CCD25199.1 - 2e-06 27.4 2.6 3.6e-06 26.5 2.6 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DNAJ_related PF12339.8 CCD25199.1 - 0.049 13.9 3.4 0.1 12.8 3.4 1.6 1 0 0 1 1 1 0 DNA-J related protein tRNA-synt_2c PF01411.19 CCD25200.1 - 1.9e-228 759.5 0.5 2.7e-228 759.0 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CCD25200.1 - 5.1e-18 64.9 0.1 1.3e-17 63.6 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CCD25200.1 - 2e-15 57.4 4.1 5e-15 56.1 4.1 1.8 1 0 0 1 1 1 1 DHHA1 domain Halogen_Hydrol PF10112.9 CCD25200.1 - 0.41 10.6 2.0 23 4.9 0.4 2.3 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Glyco_transf_24 PF18404.1 CCD25201.1 - 4.8e-33 114.7 6.3 4.8e-33 114.7 6.3 2.0 2 0 0 2 2 2 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CCD25201.1 - 4.2e-16 59.7 10.4 4.3e-15 56.4 3.7 3.7 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 CCD25201.1 - 4.2e-10 39.7 2.6 3.1e-08 33.6 0.5 3.9 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 CCD25201.1 - 3.9e-06 26.9 1.6 8.6e-05 22.5 0.3 3.5 3 1 0 3 3 3 1 Thioredoxin-like domain Stealth_CR2 PF11380.8 CCD25201.1 - 0.023 14.9 0.9 0.084 13.1 0.9 2.0 1 0 0 1 1 1 0 Stealth protein CR2, conserved region 2 SdrD_B PF17210.3 CCD25201.1 - 0.077 13.2 0.1 0.34 11.2 0.1 2.1 2 0 0 2 2 2 0 SdrD B-like domain GerD PF17898.1 CCD25201.1 - 0.13 12.2 3.0 0.091 12.7 0.3 2.2 2 0 0 2 2 2 0 Spore germination GerD central core domain Fungal_trans PF04082.18 CCD25202.1 - 6.8e-35 120.4 4.3 6.8e-35 120.4 4.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD25202.1 - 3.6e-07 30.2 11.4 6.2e-07 29.4 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vta1 PF04652.16 CCD25202.1 - 0.016 15.2 0.8 0.15 12.0 0.1 2.3 1 1 1 2 2 2 0 Vta1 like SWIRM PF04433.17 CCD25203.1 - 1.3e-08 35.1 0.0 3.3e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain UQ_con PF00179.26 CCD25204.1 - 1.8e-49 167.0 0.0 2e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCD25204.1 - 0.00034 20.3 0.0 0.00041 20.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CCD25204.1 - 0.001 19.4 0.0 0.0018 18.6 0.0 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 CCD25204.1 - 0.012 15.5 0.3 0.021 14.7 0.3 1.4 1 1 0 1 1 1 0 UEV domain RPA43_OB PF17875.1 CCD25205.1 - 3.9e-32 111.5 1.2 4e-32 111.4 0.1 1.6 2 0 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 CCD25205.1 - 2.7e-12 46.9 0.0 7.8e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GTP_EFTU PF00009.27 CCD25206.1 - 3.8e-35 121.2 0.0 3.8e-35 121.2 0.0 2.5 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CCD25206.1 - 1e-20 73.8 0.0 3.7e-20 72.0 0.0 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 CCD25206.1 - 2e-14 53.7 4.4 2.3e-09 37.5 0.0 3.7 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCD25206.1 - 1.7e-06 28.1 0.0 1.7e-06 28.1 0.0 3.4 4 0 0 4 4 4 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CCD25206.1 - 7.5e-06 25.8 0.1 2.5e-05 24.1 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 CCD25206.1 - 0.00022 21.4 0.0 0.00022 21.4 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 CCD25206.1 - 0.011 15.2 0.0 0.073 12.6 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 CCD25206.1 - 0.025 14.3 0.0 0.025 14.3 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Pyrophosphatase PF00719.19 CCD25207.1 - 5e-56 188.9 0.5 7e-56 188.5 0.5 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Acetate_kinase PF00871.17 CCD25208.1 - 0.0062 15.3 0.0 0.0088 14.8 0.0 1.2 1 0 0 1 1 1 1 Acetokinase family HLH PF00010.26 CCD25209.1 - 1.9e-20 72.5 0.2 6.3e-20 70.9 0.2 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ASD1 PF08688.10 CCD25209.1 - 0.095 13.1 9.5 0.031 14.7 2.4 2.3 1 1 1 2 2 2 0 Apx/Shroom domain ASD1 IMS PF00817.20 CCD25210.1 - 4e-25 88.6 0.0 3.6e-24 85.5 0.0 2.3 1 1 0 1 1 1 1 impB/mucB/samB family BRCT_2 PF16589.5 CCD25210.1 - 1.5e-11 44.5 0.1 5.9e-11 42.6 0.1 2.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CCD25210.1 - 1.6e-09 38.0 0.4 8.1e-09 35.7 0.4 2.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_C PF11799.8 CCD25210.1 - 5e-08 33.7 0.0 1.2e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain REV1_C PF16727.5 CCD25210.1 - 2e-05 24.9 0.0 3.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain PTCB-BRCT PF12738.7 CCD25210.1 - 7.2e-05 22.7 0.1 0.00019 21.3 0.1 1.8 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 CCD25210.1 - 8.1e-05 22.8 0.2 0.00028 21.1 0.0 2.0 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 CCD25210.1 - 0.00084 19.5 0.0 0.0027 17.9 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif mCpol PF18182.1 CCD25210.1 - 0.031 14.6 0.9 0.14 12.5 0.0 2.6 3 0 0 3 3 3 0 minimal CRISPR polymerase domain SpoIIIAH PF12685.7 CCD25210.1 - 0.49 10.2 5.8 1.3 8.8 5.8 1.7 1 0 0 1 1 1 0 SpoIIIAH-like protein PK PF00224.21 CCD25211.1 - 5.8e-164 545.0 3.0 7.4e-164 544.7 3.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CCD25211.1 - 8.3e-32 109.9 0.0 1.9e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CCD25211.1 - 0.0014 17.8 0.2 0.0028 16.8 0.1 1.6 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family ATP-synt_ab PF00006.25 CCD25212.1 - 3.8e-72 242.4 0.0 5.2e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CCD25212.1 - 1.8e-46 157.5 0.6 3.2e-46 156.7 0.6 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CCD25212.1 - 3.6e-16 59.4 1.4 1.2e-15 57.8 1.4 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Tex_N PF09371.10 CCD25212.1 - 0.043 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Tex-like protein N-terminal domain Peptidase_M41 PF01434.18 CCD25213.1 - 2.1e-60 203.8 0.2 3.9e-60 203.0 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CCD25213.1 - 8.1e-44 149.2 0.1 2.2e-43 147.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCD25213.1 - 9.8e-07 28.5 0.0 2.7e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CCD25213.1 - 2.5e-05 24.3 0.0 0.00014 21.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CCD25213.1 - 5.3e-05 23.4 0.0 0.00018 21.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CCD25213.1 - 0.00015 21.6 0.0 0.00049 19.9 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCD25213.1 - 0.00018 21.8 0.3 0.026 14.8 0.3 3.0 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 CCD25213.1 - 0.00029 20.2 0.0 0.00072 18.9 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 CCD25213.1 - 0.00092 19.6 2.4 0.0026 18.2 0.7 2.4 2 1 0 2 2 1 1 AAA ATPase domain AAA_14 PF13173.6 CCD25213.1 - 0.0019 18.3 0.0 0.0053 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CCD25213.1 - 0.013 14.8 0.0 0.14 11.5 0.0 2.3 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 CCD25213.1 - 0.014 15.2 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 CCD25213.1 - 0.02 14.9 0.1 0.29 11.1 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CCD25213.1 - 0.026 15.1 0.2 0.098 13.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 CCD25213.1 - 0.041 13.3 0.4 0.089 12.2 0.4 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 CCD25213.1 - 0.045 12.8 0.8 4.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 CCD25213.1 - 0.055 13.0 0.2 0.14 11.7 0.2 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CCD25213.1 - 0.068 13.1 1.4 0.74 9.7 0.1 2.7 2 1 1 3 3 3 0 NTPase DUF815 PF05673.13 CCD25213.1 - 0.071 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 CCD25213.1 - 0.079 12.7 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 CCD25213.1 - 0.094 12.3 0.1 0.82 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CCD25213.1 - 0.12 12.8 0.1 0.45 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CCD25213.1 - 0.12 11.8 0.3 0.32 10.4 0.3 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 CCD25213.1 - 0.12 12.0 0.2 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CCD25213.1 - 0.13 12.0 0.0 0.41 10.3 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain Cnd2 PF05786.14 CCD25214.1 - 1.2e-135 454.1 49.7 2.1e-135 453.3 49.7 1.3 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 CCD25214.1 - 0.00034 20.8 0.1 0.00034 20.8 0.1 3.2 3 0 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal 4HBT PF03061.22 CCD25215.1 - 1.9e-05 24.9 0.0 2.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Rox3 PF08633.10 CCD25216.1 - 4.9e-38 131.5 2.5 1e-37 130.4 2.5 1.4 1 1 0 1 1 1 1 Rox3 mediator complex subunit Ribosomal_L32e PF01655.18 CCD25217.1 - 6.7e-46 155.2 1.8 7.9e-46 154.9 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 SPACA7 PF15307.6 CCD25217.1 - 0.17 12.2 0.1 0.37 11.1 0.0 1.6 1 1 1 2 2 2 0 Sperm acrosome-associated protein 7 Aa_trans PF01490.18 CCD25218.1 - 1.3e-109 366.6 24.4 1.5e-109 366.4 24.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PI3_PI4_kinase PF00454.27 CCD25219.1 - 1.6e-56 191.9 0.0 4.2e-56 190.5 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 CCD25219.1 - 2.7e-26 92.5 2.1 1.7e-25 89.9 2.1 2.6 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 CCD25219.1 - 2.9e-12 46.2 0.0 6.5e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPR_22 PF18833.1 CCD25219.1 - 0.11 12.6 0.1 1.4 9.1 0.1 3.0 1 0 0 1 1 1 0 Tetratricopeptide repeat HU-CCDC81_euk_2 PF18289.1 CCD25219.1 - 2.1 8.6 5.0 4.3 7.6 0.1 3.6 4 0 0 4 4 4 0 CCDC81 eukaryotic HU domain 2 Ribosomal_L14 PF00238.19 CCD25220.1 - 1.3e-33 115.7 0.0 1.5e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TPR_1 PF00515.28 CCD25221.1 - 4e-34 115.0 5.3 5.2e-08 32.4 0.0 8.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 CCD25221.1 - 2.3e-32 108.5 3.5 2.7e-06 27.1 0.1 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 CCD25221.1 - 8.9e-28 94.2 8.6 0.00021 21.2 0.0 8.8 8 0 0 8 8 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD25221.1 - 1.7e-20 73.0 27.5 3e-14 53.0 4.1 4.5 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CCD25221.1 - 3.5e-16 59.5 0.0 1.1e-05 26.0 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CCD25221.1 - 1.8e-13 49.9 0.1 0.046 13.4 0.0 6.4 4 1 2 6 6 6 3 TPR repeat TPR_12 PF13424.6 CCD25221.1 - 5.8e-12 45.7 0.1 0.08 13.2 0.0 5.6 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CCD25221.1 - 3.7e-11 42.9 0.0 0.17 12.8 0.0 6.1 2 1 4 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCD25221.1 - 2.5e-09 36.5 0.0 2 8.6 0.0 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCD25221.1 - 7.3e-09 36.0 0.0 0.092 13.3 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CCD25221.1 - 5e-08 33.1 5.1 3.5 8.5 0.0 6.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCD25221.1 - 3.9e-07 30.0 5.1 1.9 9.0 0.0 7.3 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 CCD25221.1 - 4.5e-06 26.1 0.0 0.021 14.1 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CCD25221.1 - 2.5e-05 24.3 0.0 0.0016 18.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat PH PF00169.29 CCD25222.1 - 1.7e-16 60.6 0.1 1.7e-16 60.6 0.1 3.0 2 1 1 3 3 3 1 PH domain SAM_2 PF07647.17 CCD25222.1 - 2.3e-13 50.0 0.2 4.7e-13 49.0 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 CCD25222.1 - 7.7e-10 38.2 0.2 1.8e-09 37.1 0.2 1.6 1 0 0 1 1 1 1 SH3 domain PH_8 PF15409.6 CCD25222.1 - 5.6e-08 32.9 0.6 1.6e-06 28.3 0.0 3.3 3 0 0 3 3 3 1 Pleckstrin homology domain SH3_9 PF14604.6 CCD25222.1 - 1.4e-07 31.2 0.0 3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCD25222.1 - 7.6e-06 25.5 0.0 2.1e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 CCD25222.1 - 1.8e-05 25.1 0.2 4.6e-05 23.8 0.2 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NT-C2 PF10358.9 CCD25223.1 - 9e-41 139.0 5.1 9e-41 139.0 5.1 2.2 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins PAP2_3 PF14378.6 CCD25224.1 - 5.9e-25 88.1 11.5 5.9e-25 88.1 11.5 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 CCD25224.1 - 1.2e-12 47.8 14.1 1.6e-12 47.4 7.1 2.5 2 0 0 2 2 2 2 PAP2 superfamily Orf78 PF06024.12 CCD25224.1 - 0.45 10.8 0.1 0.45 10.8 0.1 2.0 2 0 0 2 2 2 0 Orf78 (ac78) ALG3 PF05208.13 CCD25225.1 - 3e-131 438.1 26.7 3.7e-131 437.8 26.7 1.1 1 0 0 1 1 1 1 ALG3 protein LisH PF08513.11 CCD25226.1 - 0.00022 21.0 0.2 0.00058 19.7 0.2 1.8 1 0 0 1 1 1 1 LisH DUF5349 PF17298.2 CCD25227.1 - 4.7e-14 52.9 102.0 6.2e-14 52.5 27.1 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5349) MCM_lid PF17855.1 CCD25227.1 - 0.1 13.0 0.2 0.1 13.0 0.2 1.9 2 0 0 2 2 2 0 MCM AAA-lid domain GatB_N PF02934.15 CCD25228.1 - 9.2e-90 300.7 0.1 1.2e-89 300.4 0.1 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 CCD25228.1 - 5.5e-24 84.7 4.8 1.1e-23 83.8 4.8 1.5 1 0 0 1 1 1 1 GatB domain DUF2202 PF09968.9 CCD25228.1 - 0.01 15.7 0.8 1.1 9.0 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein domain (DUF2202) Nucleoporin_C PF03177.14 CCD25229.1 - 2.8e-133 445.8 9.6 1.2e-132 443.7 9.6 1.9 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 CCD25229.1 - 2.2e-120 402.4 17.6 2.2e-120 402.4 17.6 2.7 3 0 0 3 3 3 1 Nup133 N terminal like Atg8 PF02991.16 CCD25230.1 - 1.6e-49 166.4 0.1 1.8e-49 166.2 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CCD25230.1 - 2.5e-05 24.6 0.0 3.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 tRNA-synt_1 PF00133.22 CCD25231.1 - 5.7e-244 810.9 1.7 1.1e-243 809.9 0.3 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CCD25231.1 - 1.8e-26 92.9 0.1 7.3e-26 90.9 0.0 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CCD25231.1 - 2.3e-16 59.6 2.4 2.3e-05 23.4 0.4 3.5 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CCD25231.1 - 0.00042 19.8 0.0 0.0013 18.2 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF2766 PF10964.8 CCD25231.1 - 0.094 12.7 0.7 1.5 8.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2766) HSP70 PF00012.20 CCD25232.1 - 4e-255 847.6 8.2 4.6e-255 847.5 8.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCD25232.1 - 1.1e-15 57.4 0.0 2.1e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CCD25232.1 - 0.0028 17.4 0.0 0.0068 16.2 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 CCD25232.1 - 0.03 13.6 0.2 0.11 11.8 0.0 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DDR PF08841.10 CCD25232.1 - 0.051 12.6 1.8 0.87 8.5 0.2 2.7 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain GARP PF16731.5 CCD25232.1 - 4.8 6.8 15.9 1.7 8.3 0.1 2.3 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Ribosomal_S8e PF01201.22 CCD25233.1 - 1.1e-56 190.8 2.1 1.3e-56 190.6 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e UQ_con PF00179.26 CCD25234.1 - 7e-22 77.6 0.1 1.2e-21 76.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4484 PF14831.6 CCD25234.1 - 0.034 14.2 0.5 0.051 13.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Orthopox_B11R PF07033.11 CCD25234.1 - 1 9.2 9.0 1.1 9.1 5.6 2.1 1 1 1 2 2 2 0 Orthopoxvirus B11R protein UCH PF00443.29 CCD25235.1 - 6.4e-54 183.1 26.0 6.4e-54 183.1 26.0 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCD25235.1 - 9.8e-21 74.7 3.7 9.8e-21 74.7 3.7 3.7 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Csm1_N PF18504.1 CCD25235.1 - 0.3 11.5 3.4 1.1 9.6 3.4 2.1 1 0 0 1 1 1 0 Csm1 N-terminal domain MBD_C PF14048.6 CCD25235.1 - 1.5 9.6 4.7 0.54 11.0 0.6 2.3 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 Fungal_trans PF04082.18 CCD25236.1 - 3.9e-22 78.6 0.9 3.9e-22 78.6 0.9 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD25236.1 - 2.1e-09 37.3 9.8 3.6e-09 36.6 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Daxx PF03344.15 CCD25236.1 - 0.016 15.3 0.0 0.074 13.1 0.0 2.0 2 0 0 2 2 2 0 Daxx N-terminal Rassf1C-interacting domain AhpC-TSA PF00578.21 CCD25237.1 - 9e-32 109.6 0.1 1.3e-31 109.1 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 CCD25237.1 - 8e-13 48.0 0.0 1.5e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 CCD25237.1 - 8.1e-10 38.6 0.0 1.5e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Redoxin TatD_DNase PF01026.21 CCD25238.1 - 1.3e-39 136.1 0.0 1.9e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Putative_G5P PF17426.2 CCD25238.1 - 0.044 13.9 0.1 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Putative Gamma DNA binding protein G5P DUF4777 PF16007.5 CCD25238.1 - 0.068 13.4 0.6 0.15 12.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) PP2C PF00481.21 CCD25239.1 - 9.1e-68 228.7 0.1 1.7e-67 227.8 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PTH2 PF01981.16 CCD25241.1 - 5.4e-44 149.2 0.7 8e-44 148.7 0.0 1.6 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 ArAE_2 PF10334.9 CCD25241.1 - 0.038 13.8 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 O-antigen_lig PF13425.6 CCD25241.1 - 1.2 7.9 2.4 1.6 7.4 2.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF3464 PF11947.8 CCD25241.1 - 3.7 7.3 4.6 1.9 8.2 2.5 1.6 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 SEP PF08059.13 CCD25242.1 - 5e-23 81.5 0.3 1.2e-22 80.3 0.3 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 CCD25242.1 - 8.5e-17 61.1 0.1 1.5e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CCD25242.1 - 1.5e-08 34.3 0.9 2.8e-08 33.4 0.9 1.5 1 0 0 1 1 1 1 UBA-like domain Cmc1 PF08583.10 CCD25244.1 - 3.4e-17 62.2 7.5 3.4e-17 62.2 7.5 1.6 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CBM_14 PF01607.24 CCD25244.1 - 0.051 13.8 0.7 0.076 13.2 0.7 1.3 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain CHCH PF06747.13 CCD25244.1 - 0.07 13.3 2.6 6.3 7.1 0.3 2.4 2 0 0 2 2 2 0 CHCH domain Sec7 PF01369.20 CCD25245.1 - 1.1e-14 54.5 0.4 3.2e-14 53.0 0.4 1.7 1 0 0 1 1 1 1 Sec7 domain DASH_Dad2 PF08654.10 CCD25245.1 - 0.14 12.6 2.9 0.34 11.3 0.2 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad2 DUF3439 PF11921.8 CCD25245.1 - 0.21 11.6 5.2 0.62 10.0 5.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 CCD25245.1 - 2.3 8.2 13.6 3.8 7.5 12.0 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Sel1 PF08238.12 CCD25246.1 - 3.6e-42 141.9 20.0 1.7e-06 28.5 0.1 7.8 8 0 0 8 8 8 7 Sel1 repeat Kinesin PF00225.23 CCD25247.1 - 1.6e-107 359.3 3.2 1.6e-107 359.3 3.2 3.1 4 1 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 CCD25247.1 - 1.2e-24 87.0 0.0 1.2e-24 87.0 0.0 4.1 3 1 0 3 3 3 1 Microtubule binding SlyX PF04102.12 CCD25247.1 - 1.7 9.3 12.6 0.3 11.8 1.4 4.2 2 1 0 2 2 2 0 SlyX Myb_DNA-binding PF00249.31 CCD25248.1 - 2e-11 43.9 3.7 1.4e-10 41.1 0.7 2.9 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCD25248.1 - 8.5e-11 41.9 4.7 4.9e-10 39.5 1.1 3.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 CCD25248.1 - 0.13 12.4 0.5 4.1 7.6 0.1 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 CCD25248.1 - 0.25 11.8 2.6 5.8 7.4 0.4 3.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Transp_cyt_pur PF02133.15 CCD25249.1 - 1.5e-96 323.9 34.3 1.7e-96 323.7 34.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NA37 PF04245.13 CCD25249.1 - 0.046 13.2 0.9 0.062 12.8 0.9 1.1 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein Transp_cyt_pur PF02133.15 CCD25250.1 - 2.6e-92 309.9 40.1 3.1e-92 309.7 40.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin VIT1 PF01988.19 CCD25250.1 - 0.1 12.4 0.1 0.1 12.4 0.1 2.8 4 0 0 4 4 4 0 VIT family HisG PF01634.18 CCD25251.1 - 2.7e-52 177.0 0.2 3.6e-52 176.5 0.2 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 CCD25251.1 - 6.9e-26 90.2 0.0 1.1e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain CBM_21 PF03370.13 CCD25252.1 - 1.7e-28 99.0 1.3 1.7e-28 99.0 1.3 2.0 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CCD25252.1 - 1.5e-11 44.7 2.7 4.5e-11 43.2 2.7 1.9 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Tox-URI2 PF15653.6 CCD25252.1 - 0.61 10.4 3.6 1.6 9.1 0.8 2.8 2 1 0 2 2 2 0 URI fold toxin 2 Mito_carr PF00153.27 CCD25254.1 - 5.6e-47 157.6 6.6 9.3e-18 64.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MMR1 PF08505.10 CCD25255.1 - 4.6e-77 259.8 25.2 4.6e-77 259.8 25.2 3.6 2 1 1 3 3 3 1 Mitochondrial Myo2 receptor-related protein Peroxin-13_N PF04088.13 CCD25256.1 - 1.1e-50 171.6 1.1 2e-50 170.8 1.1 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 CCD25256.1 - 5.6e-09 35.5 0.0 1.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCD25256.1 - 4.9e-08 32.7 0.0 1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCD25256.1 - 6.3e-08 32.2 0.0 1.6e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CCD25256.1 - 0.015 15.5 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain eIF3_subunit PF08597.10 CCD25257.1 - 1.9e-47 162.2 19.0 2.9e-47 161.6 19.0 1.3 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit GvpL_GvpF PF06386.11 CCD25257.1 - 0.021 14.8 1.6 0.033 14.1 1.6 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF PRELI PF04707.14 CCD25258.1 - 6.1e-50 169.1 0.6 7.2e-50 168.9 0.6 1.0 1 0 0 1 1 1 1 PRELI-like family NMT_C PF02799.15 CCD25260.1 - 2e-80 269.3 3.6 2.9e-80 268.7 3.6 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 CCD25260.1 - 3.9e-76 254.3 1.1 7.8e-76 253.3 0.1 2.0 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 CCD25260.1 - 7.3e-05 22.9 0.0 0.0016 18.5 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CCD25260.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 CCD25260.1 - 0.084 13.5 0.0 0.22 12.2 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain WD40 PF00400.32 CCD25261.1 - 1.2e-07 32.3 7.0 0.0018 19.1 0.2 5.7 6 0 0 6 6 6 1 WD domain, G-beta repeat Nup160 PF11715.8 CCD25261.1 - 8e-05 21.5 1.7 0.00042 19.1 0.6 2.3 2 1 0 2 2 2 1 Nucleoporin Nup120/160 SUKH_6 PF14568.6 CCD25261.1 - 0.0031 17.9 0.1 0.0031 17.9 0.1 2.8 2 1 0 2 2 2 1 SMI1-KNR4 cell-wall ANAPC4_WD40 PF12894.7 CCD25261.1 - 0.02 15.2 0.4 1.1 9.6 0.2 3.1 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SPATA9 PF15824.5 CCD25261.1 - 0.022 14.1 0.0 3.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated protein 9 PQQ_3 PF13570.6 CCD25261.1 - 0.036 14.6 0.1 0.89 10.1 0.0 3.1 4 0 0 4 4 4 0 PQQ-like domain PQQ PF01011.21 CCD25261.1 - 0.11 12.5 0.2 4.3 7.4 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat Kelch_5 PF13854.6 CCD25261.1 - 0.14 12.1 0.5 13 5.9 0.0 2.8 2 0 0 2 2 2 0 Kelch motif POC1 PF10450.9 CCD25262.1 - 7.9e-73 244.8 0.5 8.8e-73 244.6 0.5 1.0 1 0 0 1 1 1 1 POC1 chaperone Prefoldin_2 PF01920.20 CCD25263.1 - 4.4e-25 87.7 8.8 4.7e-25 87.6 8.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF5082 PF16888.5 CCD25263.1 - 0.0052 17.0 7.5 0.25 11.6 7.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) Sec2p PF06428.11 CCD25263.1 - 0.0055 16.6 8.6 0.16 12.0 1.3 2.1 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p MIP-T3_C PF17749.1 CCD25263.1 - 0.006 16.6 2.4 0.006 16.6 2.4 1.8 1 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region UPF0242 PF06785.11 CCD25263.1 - 0.009 16.1 8.3 0.0098 16.0 8.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF1732 PF08340.11 CCD25263.1 - 0.021 14.8 1.8 0.035 14.1 1.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) DUF1192 PF06698.11 CCD25263.1 - 0.026 14.5 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Prefoldin PF02996.17 CCD25263.1 - 0.028 14.3 4.8 0.033 14.1 0.3 2.0 1 1 0 2 2 2 0 Prefoldin subunit BRE1 PF08647.11 CCD25263.1 - 0.032 14.3 4.2 2 8.6 0.2 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase HAUS5 PF14817.6 CCD25263.1 - 0.049 12.4 6.1 0.52 9.0 5.1 1.9 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 5 CENP-F_leu_zip PF10473.9 CCD25263.1 - 0.053 13.5 7.1 0.79 9.7 0.7 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 JIP_LZII PF16471.5 CCD25263.1 - 0.095 12.9 5.5 0.21 11.7 0.3 2.5 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Bcr-Abl_Oligo PF09036.10 CCD25263.1 - 0.23 11.5 3.4 0.35 10.9 0.7 2.1 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Spc24 PF08286.11 CCD25263.1 - 0.29 11.4 7.8 3.5 7.9 1.2 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Med4 PF10018.9 CCD25263.1 - 0.41 10.3 5.0 0.1 12.3 1.2 1.7 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 APG6_N PF17675.1 CCD25263.1 - 0.51 10.9 8.2 3.7 8.1 8.2 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF5595 PF18077.1 CCD25263.1 - 1.2 9.3 5.0 5.6 7.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) TMPIT PF07851.13 CCD25263.1 - 1.2 8.3 5.4 0.76 9.0 1.2 1.9 1 1 1 2 2 2 0 TMPIT-like protein COQ9 PF08511.11 CCD25264.1 - 3.4e-20 71.6 0.2 8.5e-20 70.3 0.0 1.8 2 0 0 2 2 2 1 COQ9 Jag_N PF14804.6 CCD25264.1 - 0.17 12.3 0.0 15 6.0 0.0 2.4 2 0 0 2 2 2 0 Jag N-terminus zf-Mss51 PF13824.6 CCD25265.1 - 4.6e-18 65.1 3.4 5.4e-17 61.6 1.1 2.4 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.11 CCD25265.1 - 0.07 12.9 0.7 0.28 11.0 0.3 2.2 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain DUF1713 PF08213.11 CCD25266.1 - 3.6e-12 46.0 24.0 6.1e-12 45.2 24.0 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) U3_assoc_6 PF08640.11 CCD25266.1 - 0.015 15.3 4.5 0.032 14.3 2.8 2.2 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Heme_oxygenase PF01126.20 CCD25267.1 - 2.4e-13 50.4 5.9 3.5e-11 43.3 5.9 2.8 1 1 0 1 1 1 1 Heme oxygenase MRP-S28 PF10213.9 CCD25267.1 - 0.006 17.0 1.1 0.006 17.0 1.1 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein Ribosomal_S18 PF01084.20 CCD25268.1 - 1.5e-17 63.6 0.3 8.8e-17 61.1 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S18 Ofd1_CTDD PF10637.9 CCD25269.1 - 2.6e-85 285.9 4.1 8.2e-83 277.7 4.2 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 CCD25269.1 - 8.8e-27 93.6 0.0 6.3e-26 90.9 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 CCD25269.1 - 2e-15 57.5 0.0 5.3e-15 56.1 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CCD25269.1 - 0.019 15.4 0.0 0.041 14.4 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Staphostatin_A PF09022.10 CCD25269.1 - 0.02 14.8 0.7 0.049 13.5 0.7 1.6 1 0 0 1 1 1 0 Staphostatin A Ndc80_HEC PF03801.13 CCD25269.1 - 0.069 12.8 2.2 0.16 11.6 2.2 1.6 1 0 0 1 1 1 0 HEC/Ndc80p family Complex1_LYR PF05347.15 CCD25270.1 - 9.1e-15 54.5 3.0 1.2e-14 54.1 3.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 CCD25270.1 - 0.00019 22.0 0.1 0.00022 21.8 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 CCD25270.1 - 0.0007 20.3 1.4 0.00082 20.1 1.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF5584 PF17822.1 CCD25270.1 - 0.0081 15.7 0.4 0.009 15.5 0.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5584) Mesothelin PF06060.12 CCD25270.1 - 0.089 11.0 0.3 0.1 10.8 0.3 1.2 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) DnaJ-X PF14308.6 CCD25273.1 - 3.4e-60 203.1 13.3 3.4e-60 203.1 13.3 1.9 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CCD25273.1 - 7.6e-27 93.2 0.4 6.9e-26 90.2 0.3 2.6 2 0 0 2 2 2 1 DnaJ domain Metal_resist PF13801.6 CCD25273.1 - 0.038 14.2 0.2 0.11 12.6 0.2 1.8 1 0 0 1 1 1 0 Heavy-metal resistance PurS PF02700.14 CCD25273.1 - 0.24 11.6 3.1 5.3 7.3 0.1 2.7 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine (FGAM) synthase BRD4_CDT PF17105.5 CCD25273.1 - 0.26 10.9 8.1 0.033 13.8 3.5 1.9 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 DUF2205 PF10224.9 CCD25273.1 - 3.2 7.8 10.7 0.48 10.5 4.4 2.5 2 1 0 2 2 2 0 Short coiled-coil protein Arrestin_C PF02752.22 CCD25274.1 - 2.6e-08 34.4 14.1 1.4e-06 28.8 2.9 5.0 3 3 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Got1 PF04178.12 CCD25275.1 - 1.6e-31 109.0 20.2 1.6e-31 109.0 20.2 1.5 1 1 1 2 2 2 1 Got1/Sft2-like family DUF2207 PF09972.9 CCD25275.1 - 1.7 7.3 11.1 59 2.2 11.1 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) HLH PF00010.26 CCD25276.1 - 1.8e-12 47.0 0.1 3.8e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zinc_ribbon_16 PF17034.5 CCD25277.1 - 1.9e-25 89.5 14.8 6.9e-18 65.1 6.1 2.9 2 1 1 3 3 3 2 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 CCD25277.1 - 1.6e-06 27.6 6.8 4.1e-06 26.3 6.8 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 CCD25277.1 - 0.085 13.8 3.9 3.6 8.6 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat zf-RING_2 PF13639.6 CCD25277.1 - 1.5 9.2 10.6 1.8 9.0 4.1 3.3 3 0 0 3 3 3 0 Ring finger domain Pkinase PF00069.25 CCD25278.1 - 6.3e-60 202.8 0.0 1.9e-59 201.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25278.1 - 7.4e-35 120.5 0.0 1.6e-34 119.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 CCD25278.1 - 1.8e-21 76.0 11.2 5.2e-14 52.1 3.7 2.8 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 CCD25278.1 - 8.9e-19 67.1 38.1 1.7e-11 43.8 15.1 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 CCD25278.1 - 1.4e-12 48.1 2.0 5.5e-12 46.2 2.0 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 CCD25278.1 - 7.3e-07 29.4 0.3 3.2e-06 27.4 0.1 2.2 2 0 0 2 2 2 1 C2 domain Kinase-like PF14531.6 CCD25278.1 - 2.8e-05 23.6 0.0 0.00028 20.3 0.0 2.3 1 1 1 2 2 2 1 Kinase-like RNA_polI_A14 PF08203.11 CCD25278.1 - 0.11 13.2 0.6 0.91 10.3 0.6 2.8 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Lgl_C PF08596.10 CCD25279.1 - 3.4e-139 463.9 0.7 7.9e-139 462.7 0.5 1.7 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 CCD25279.1 - 4.7e-07 30.0 0.1 0.11 12.9 0.0 5.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCD25279.1 - 2.5e-05 24.9 0.0 7.4 7.6 0.0 4.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.11 CCD25279.1 - 8.9e-05 21.4 1.6 0.3 9.8 0.1 3.3 3 0 0 3 3 3 3 Nup133 N terminal like RAB3GAP2_N PF14655.6 CCD25279.1 - 0.16 11.2 3.5 10 5.3 0.1 3.2 3 1 1 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cid2 PF09774.9 CCD25280.1 - 5.8e-38 130.8 7.9 8.2e-38 130.3 7.9 1.2 1 0 0 1 1 1 1 Caffeine-induced death protein 2 AIM24 PF01987.17 CCD25281.1 - 5.8e-23 81.7 0.0 8.3e-22 78.0 0.0 2.1 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 NuA4 PF09340.10 CCD25282.1 - 1e-23 83.0 0.7 2.4e-23 81.8 0.7 1.7 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 AalphaY_MDB PF04611.12 CCD25282.1 - 0.16 12.0 0.1 1.6 8.7 0.1 2.1 2 0 0 2 2 2 0 Mating type protein A alpha Y mating type dependent binding region PCI PF01399.27 CCD25284.1 - 1.8e-11 44.4 2.3 4.4e-05 23.9 0.0 3.2 3 0 0 3 3 3 2 PCI domain Tmemb_14 PF03647.13 CCD25286.1 - 5.9e-14 52.6 8.1 7.2e-14 52.3 8.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Phage_holin_5_2 PF16079.5 CCD25286.1 - 0.1 13.0 3.0 0.23 11.8 0.4 2.1 1 1 1 2 2 2 0 Phage holin family Hol44, in holin superfamily V AA_kinase PF00696.28 CCD25287.1 - 2.2e-39 135.5 0.0 4.7e-39 134.4 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 CCD25287.1 - 1.8e-11 43.6 0.4 0.00012 21.7 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 CCD25287.1 - 5e-08 32.6 1.8 1.6e-05 24.6 0.4 2.6 2 0 0 2 2 2 2 ACT domain Sec61_beta PF03911.16 CCD25289.1 - 9.2e-18 64.0 1.3 1.1e-17 63.7 1.3 1.1 1 0 0 1 1 1 1 Sec61beta family MOZ_SAS PF01853.18 CCD25290.1 - 3.4e-68 228.8 2.4 5.7e-68 228.1 2.4 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CCD25290.1 - 3.4e-15 55.4 5.2 3.4e-15 55.4 5.2 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain DUF5470 PF17564.2 CCD25290.1 - 2.9 8.1 5.8 0.57 10.4 0.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5470) Ribosomal_L34e PF01199.18 CCD25291.1 - 3.2e-42 142.8 3.8 3.2e-42 142.8 3.8 1.6 2 0 0 2 2 2 1 Ribosomal protein L34e FhuF_C PF11575.8 CCD25291.1 - 0.2 11.6 2.7 7.4 6.6 0.1 2.4 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Ribonuc_L-PSP PF01042.21 CCD25292.1 - 1.1e-40 138.4 0.5 1.2e-40 138.3 0.5 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP PET117 PF15786.5 CCD25293.1 - 3.7e-31 107.2 0.5 5.1e-31 106.8 0.5 1.2 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Cyclin PF08613.11 CCD25294.1 - 4.3e-27 95.4 1.9 8.1e-27 94.6 1.9 1.8 1 1 0 1 1 1 1 Cyclin Transp_cyt_pur PF02133.15 CCD25295.1 - 1.2e-95 320.9 34.8 1.4e-95 320.7 34.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ketoacyl-synt PF00109.26 CCD25296.1 - 1.6e-54 185.2 0.0 2.2e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CCD25296.1 - 1.1e-34 118.9 0.0 1.8e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 CCD25296.1 - 0.0028 17.0 0.1 0.0058 16.0 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain HAD_2 PF13419.6 CCD25297.1 - 9.5e-17 61.6 0.0 1.2e-16 61.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCD25297.1 - 9.6e-10 39.1 0.0 1.6e-07 31.9 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCD25297.1 - 0.0052 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 CCD25297.1 - 0.013 16.0 0.0 0.017 15.5 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Vhr1 PF04001.13 CCD25298.1 - 1.2e-44 150.5 4.4 2.4e-44 149.5 4.4 1.5 1 0 0 1 1 1 1 Transcription factor Vhr1 Sen15 PF09631.10 CCD25298.1 - 0.084 13.2 1.6 1.1 9.6 0.1 2.8 2 1 0 2 2 2 0 Sen15 protein ICL PF00463.21 CCD25299.1 - 6.5e-283 939.0 0.8 7.5e-283 938.8 0.8 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CCD25299.1 - 6.5e-10 38.9 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Flo11 PF10182.9 CCD25300.1 - 6.9e-72 240.5 5.7 1.3e-71 239.6 5.7 1.5 1 0 0 1 1 1 1 Flo11 domain Staphostatin_A PF09022.10 CCD25300.1 - 0.51 10.3 3.7 6.4 6.7 0.2 2.4 2 0 0 2 2 2 0 Staphostatin A RGI1 PF10843.8 CCD25301.1 - 6.4e-28 97.7 15.0 1.4e-27 96.6 15.0 1.4 1 1 0 1 1 1 1 Respiratory growth induced protein 1 zf-RING_4 PF14570.6 CCD25302.1 - 3.4e-20 71.6 13.0 6.9e-20 70.6 13.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CCD25302.1 - 7.8e-07 28.9 7.1 7.8e-07 28.9 7.1 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CCD25302.1 - 1.1e-05 25.1 0.1 4.3e-05 23.3 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.12 CCD25302.1 - 4.2e-05 23.1 0.9 4.2e-05 23.1 0.9 3.3 4 0 0 4 4 4 1 Rtf2 RING-finger Baculo_IE-1 PF05290.11 CCD25302.1 - 0.00012 22.0 3.4 0.00028 20.8 3.4 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) SUIM_assoc PF16619.5 CCD25302.1 - 0.0006 19.8 1.0 0.0006 19.8 1.0 4.6 4 1 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 zf-RING_2 PF13639.6 CCD25302.1 - 0.0018 18.6 10.1 0.0034 17.7 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain SET_assoc PF11767.8 CCD25302.1 - 0.0056 16.3 0.2 0.043 13.5 0.0 2.3 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated Prok-RING_4 PF14447.6 CCD25302.1 - 0.0077 16.1 8.6 0.1 12.5 9.0 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CCD25302.1 - 0.0089 15.9 10.4 0.019 14.8 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Nup35_RRM_2 PF14605.6 CCD25302.1 - 0.051 13.6 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-UDP PF14569.6 CCD25302.1 - 0.068 13.3 4.4 0.14 12.3 4.4 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_5 PF14634.6 CCD25302.1 - 0.11 12.4 9.5 0.24 11.4 9.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain CDC45 PF02724.14 CCD25302.1 - 0.15 10.3 9.5 0.061 11.6 0.4 2.7 3 0 0 3 3 3 0 CDC45-like protein FYDLN_acid PF09538.10 CCD25302.1 - 6.7 7.4 12.1 2 9.2 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-C3HC4_4 PF15227.6 CCD25302.1 - 7.4 6.8 10.7 66 3.8 10.7 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING U1snRNP70_N PF12220.8 CCD25303.1 - 6.3e-19 68.4 0.2 1.3e-18 67.4 0.2 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 CCD25303.1 - 9.5e-16 57.4 0.0 2.2e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD25303.1 - 3.7e-06 27.0 0.0 9.4e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif NAT PF04768.13 CCD25304.1 - 8e-55 185.1 0.8 1.4e-54 184.3 0.2 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 CCD25304.1 - 1.2e-29 103.3 0.0 2.4e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 CCD25304.1 - 6.6e-25 88.1 0.0 1.2e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.20 CCD25304.1 - 0.028 14.5 0.0 0.079 13.1 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus P16-Arc PF04699.14 CCD25305.1 - 1.1e-45 155.8 0.0 1.2e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 CCD25305.1 - 0.019 15.3 0.0 0.04 14.2 0.0 1.5 2 0 0 2 2 2 0 Dip2/Utp12 Family Ribonuc_red_lgC PF02867.15 CCD25306.1 - 1.9e-183 610.8 0.0 2.4e-183 610.5 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CCD25306.1 - 3.2e-23 81.5 0.0 7.9e-23 80.3 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CCD25306.1 - 1.7e-17 63.8 0.0 4.2e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain Sec6 PF06046.13 CCD25307.1 - 1.4e-166 555.3 2.7 1.4e-166 555.3 2.7 1.5 1 1 1 2 2 2 1 Exocyst complex component Sec6 AnfG_VnfG PF03139.15 CCD25307.1 - 0.024 14.7 0.9 0.24 11.5 0.1 3.1 3 0 0 3 3 3 0 Vanadium/alternative nitrogenase delta subunit Yuri_gagarin PF15934.5 CCD25307.1 - 6.3 6.6 10.9 0.07 13.0 1.1 2.7 3 0 0 3 3 3 0 Yuri gagarin Tctex-1 PF03645.13 CCD25308.1 - 1.2e-07 31.9 0.9 1.5e-07 31.6 0.9 1.2 1 0 0 1 1 1 1 Tctex-1 family Peptidase_C65 PF10275.9 CCD25308.1 - 0.038 13.4 0.7 0.059 12.8 0.4 1.4 1 1 1 2 2 2 0 Peptidase C65 Otubain DUF202 PF02656.15 CCD25309.1 - 1.1e-14 54.6 2.1 1.1e-14 54.6 2.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5337 PF17272.2 CCD25309.1 - 0.46 10.3 3.0 1.2 9.0 3.0 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5337) Aldedh PF00171.22 CCD25310.1 - 3.3e-185 616.0 0.1 3.8e-185 615.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family EutA PF06277.11 CCD25311.1 - 0.23 10.3 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA ETRAMP PF09716.10 CCD25312.1 - 1.3 9.2 4.6 7.9 6.6 2.7 2.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) HA2 PF04408.23 CCD25313.1 - 6e-20 71.5 0.1 3.5e-19 69.1 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CCD25313.1 - 2.2e-15 56.9 0.1 6.1e-15 55.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CCD25313.1 - 3.2e-15 56.2 0.0 1.2e-14 54.4 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CCD25313.1 - 2.9e-08 33.7 0.2 6.5e-08 32.5 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCD25313.1 - 8.4e-07 29.3 0.1 3e-06 27.5 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCD25313.1 - 0.00019 21.8 0.1 0.00057 20.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCD25313.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CCD25313.1 - 0.0019 17.5 0.0 0.0039 16.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 CCD25313.1 - 0.0055 15.8 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CCD25313.1 - 0.0068 16.9 0.0 0.025 15.1 0.0 2.1 1 0 0 1 1 1 1 ABC transporter SRP54 PF00448.22 CCD25313.1 - 0.0082 15.8 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ATPase PF06745.13 CCD25313.1 - 0.012 15.0 0.2 0.029 13.7 0.1 1.6 1 1 0 1 1 1 0 KaiC AAA_14 PF13173.6 CCD25313.1 - 0.018 15.0 3.5 0.27 11.2 0.6 3.6 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CCD25313.1 - 0.032 14.0 0.2 3.9 7.2 0.0 2.4 1 1 1 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 CCD25313.1 - 0.072 12.5 0.0 0.22 11.0 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein Flavi_DEAD PF07652.14 CCD25313.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.15 CCD25313.1 - 0.18 11.8 9.2 2.1 8.3 0.0 3.8 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit Peptidase_M48 PF01435.18 CCD25314.1 - 8e-32 110.6 0.0 1.9e-31 109.4 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M48 SNARE_assoc PF09335.11 CCD25315.1 - 4.8e-16 59.3 5.4 4.8e-16 59.3 5.4 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein TctB PF07331.11 CCD25315.1 - 0.0022 18.3 5.4 0.0022 18.3 5.4 2.1 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family GP41 PF00517.17 CCD25315.1 - 0.037 13.9 0.5 0.058 13.3 0.5 1.3 1 0 0 1 1 1 0 Retroviral envelope protein Tetraspanin PF00335.20 CCD25315.1 - 0.14 11.8 5.0 1.2 8.7 1.0 2.5 2 1 0 2 2 2 0 Tetraspanin family VIT1 PF01988.19 CCD25315.1 - 0.65 9.8 4.0 0.15 11.9 1.0 1.5 2 0 0 2 2 2 0 VIT family DUF3810 PF12725.7 CCD25315.1 - 1.6 8.0 7.7 0.14 11.5 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF4231 PF14015.6 CCD25315.1 - 3.4 8.2 5.9 1.5 9.4 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) MPS-4 PF17523.2 CCD25315.1 - 6.1 7.1 8.9 0.83 9.8 0.9 2.6 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 DUF997 PF06196.12 CCD25315.1 - 6.9 6.8 8.3 24 5.0 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF997) DUF3336 PF11815.8 CCD25316.1 - 2.1e-30 105.2 5.5 2.1e-30 105.2 5.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CCD25316.1 - 1e-25 91.1 0.1 5.5e-25 88.7 0.0 2.3 2 0 0 2 2 2 1 Patatin-like phospholipase LIM PF00412.22 CCD25317.1 - 2.5e-14 53.2 26.1 2.8e-09 37.1 9.1 2.5 2 0 0 2 2 2 2 LIM domain SRP40_C PF05022.12 CCD25318.1 - 2.5e-23 82.7 2.6 2.5e-23 82.7 2.6 2.8 3 0 0 3 3 3 1 SRP40, C-terminal domain PTR2 PF00854.21 CCD25319.1 - 7.6e-102 341.1 13.3 3.8e-101 338.8 13.3 1.8 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 CCD25319.1 - 8.6e-10 38.1 34.1 1.8e-08 33.7 26.1 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ubiquitin PF00240.23 CCD25320.1 - 3.7e-34 116.3 0.6 4.9e-34 115.9 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CCD25320.1 - 6.1e-31 106.1 10.4 9.3e-31 105.5 10.4 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CCD25320.1 - 2.2e-16 59.4 0.7 3e-16 59.0 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CCD25320.1 - 2e-05 24.9 0.1 7.4e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CCD25320.1 - 0.0036 17.6 0.0 0.0055 17.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CCD25320.1 - 0.0038 17.1 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CCD25320.1 - 0.0073 16.4 0.1 0.015 15.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CCD25320.1 - 0.014 15.4 1.0 4.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CCD25320.1 - 0.024 15.2 0.1 0.031 14.8 0.1 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CCD25320.1 - 0.083 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain TPR_MLP1_2 PF07926.12 CCD25321.1 - 3.5e-28 98.3 25.8 3.5e-28 98.3 25.8 16.6 6 5 8 16 16 16 4 TPR/MLP1/MLP2-like protein DUF3539 PF12058.8 CCD25321.1 - 2 8.6 5.4 4.5 7.5 0.3 4.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3539) DAGK_cat PF00781.24 CCD25322.1 - 6.3e-08 32.3 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RE_BsaWI PF18643.1 CCD25322.1 - 0.072 13.0 2.0 0.2 11.6 2.0 1.8 1 0 0 1 1 1 0 BsaWI restriction endonuclease type 2 SUIM_assoc PF16619.5 CCD25322.1 - 1.5 9.0 10.1 0.25 11.4 4.7 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pcc1 PF09341.10 CCD25323.1 - 5.7e-20 71.2 0.1 6.8e-20 71.0 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 Acetyltransf_11 PF13720.6 CCD25324.1 - 0.13 12.7 0.1 0.53 10.8 0.1 2.1 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 PEPCK_ATP PF01293.20 CCD25325.1 - 2.7e-217 722.0 0.0 3.2e-217 721.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase ATPase PF06745.13 CCD25325.1 - 0.054 12.8 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 CCD25325.1 - 0.065 13.4 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CCD25325.1 - 0.15 11.8 0.1 0.43 10.3 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Myb_DNA-binding PF00249.31 CCD25326.1 - 2.9e-28 97.8 16.2 1.4e-13 50.8 0.1 3.8 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCD25326.1 - 5.2e-27 93.9 12.7 1.7e-10 41.0 0.0 4.0 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 CCD25326.1 - 0.0086 16.1 11.2 0.58 10.2 0.0 4.6 3 1 0 4 4 4 2 SLIDE SANT_DAMP1_like PF16282.5 CCD25326.1 - 0.0093 16.1 1.3 3.4 7.9 0.1 4.2 3 1 2 5 5 5 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 CCD25326.1 - 0.023 14.8 0.0 7.2 6.8 0.0 3.5 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SKG6 PF08693.10 CCD25327.1 - 0.00026 20.3 2.4 0.00026 20.3 2.4 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF2681 PF10883.8 CCD25327.1 - 0.12 12.8 0.2 0.66 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) LapA_dom PF06305.11 CCD25327.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2981 PF11200.8 CCD25327.1 - 2.7 7.7 10.3 0.37 10.5 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) Sir1 PF11603.8 CCD25328.1 - 1.2e-34 119.4 3.5 3.5e-34 117.8 3.5 1.9 1 0 0 1 1 1 1 Regulatory protein Sir1 DEAD PF00270.29 CCD25328.1 - 9.7e-07 28.7 0.0 1.1e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCD25328.1 - 0.16 12.3 0.0 0.78 10.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain GST_N_2 PF13409.6 CCD25329.1 - 7e-14 51.9 0.0 7.3e-13 48.6 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CCD25329.1 - 2.5e-05 24.2 0.0 5.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CCD25329.1 - 0.062 13.7 0.0 0.26 11.7 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Zn_clus PF00172.18 CCD25330.1 - 1.5e-09 37.8 11.0 1.5e-09 37.8 11.0 2.4 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3445 PF11927.8 CCD25330.1 - 0.098 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) Fungal_trans_2 PF11951.8 CCD25331.1 - 4.6e-58 196.9 0.3 5.2e-58 196.7 0.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain PQ-loop PF04193.14 CCD25332.1 - 2.3e-20 72.1 16.8 1.5e-19 69.5 2.8 3.3 3 1 0 3 3 3 2 PQ loop repeat ABC2_membrane_5 PF13346.6 CCD25332.1 - 4.7 6.7 24.0 0.89 9.1 11.1 2.2 1 1 2 3 3 3 0 ABC-2 family transporter protein Cys_Met_Meta_PP PF01053.20 CCD25333.1 - 6.2e-59 199.4 0.0 1.4e-58 198.2 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CCD25333.1 - 5.3e-05 22.4 0.0 0.0001 21.4 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V SYF2 PF08231.12 CCD25333.1 - 0.041 14.3 1.2 0.075 13.4 1.2 1.4 1 0 0 1 1 1 0 SYF2 splicing factor Hyphal_reg_CWP PF11765.8 CCD25334.1 - 2.7e-45 154.7 18.2 2.7e-45 154.7 18.2 2.2 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal FH2 PF02181.23 CCD25335.1 - 2.3e-69 234.3 12.0 2.3e-69 234.3 12.0 2.7 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 CCD25335.1 - 8.2e-10 38.5 0.8 8.2e-10 38.5 0.8 3.0 3 1 1 4 4 4 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 CCD25335.1 - 5.1e-05 23.0 0.9 5.1e-05 23.0 0.9 3.2 1 1 1 2 2 2 1 Diaphanous FH3 Domain TetR_C_23 PF17931.1 CCD25335.1 - 0.67 10.1 7.2 3.3 7.9 2.3 3.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Coa1 PF08695.10 CCD25336.1 - 1.2e-38 131.5 0.0 1.7e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF1748 PF08520.10 CCD25337.1 - 1.1e-27 95.7 0.0 1.2e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) MOR2-PAG1_N PF14222.6 CCD25338.1 - 1.9e-176 588.3 12.1 1.9e-176 588.3 12.1 2.2 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 CCD25338.1 - 8e-87 291.3 2.6 9.7e-86 287.7 0.4 3.3 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 CCD25338.1 - 2.1e-24 85.4 9.0 3.7e-12 44.8 0.1 4.0 4 0 0 4 4 4 3 Cell morphogenesis central region Cnd1 PF12717.7 CCD25338.1 - 0.0027 17.8 0.2 0.0027 17.8 0.2 4.4 5 1 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 MAT1 PF06391.13 CCD25338.1 - 0.075 12.9 5.6 0.24 11.2 5.6 1.8 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 UCH PF00443.29 CCD25339.1 - 5.6e-60 203.0 5.7 5.6e-60 203.0 5.7 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCD25339.1 - 2e-19 70.4 11.3 2e-19 70.4 11.3 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 CCD25339.1 - 0.00012 22.6 0.0 0.00065 20.2 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain DUF3094 PF11293.8 CCD25339.1 - 0.34 10.7 2.7 0.77 9.5 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) DAO PF01266.24 CCD25340.1 - 2.1e-53 182.2 0.0 3.3e-53 181.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CCD25340.1 - 3.5e-38 130.3 0.0 6.3e-38 129.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 CCD25340.1 - 2.8e-10 39.9 0.1 2.3e-06 26.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 CCD25340.1 - 3.1e-09 36.7 0.2 5.8e-06 25.9 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CCD25340.1 - 8.6e-05 21.9 0.1 0.00025 20.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CCD25340.1 - 0.00012 21.3 0.5 0.0087 15.2 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CCD25340.1 - 0.0012 19.1 0.4 0.0045 17.2 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CCD25340.1 - 0.0019 17.0 0.2 0.0032 16.3 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 CCD25340.1 - 0.0036 16.6 0.1 0.045 13.0 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.19 CCD25340.1 - 0.007 15.8 0.1 0.015 14.7 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 CCD25340.1 - 0.013 14.7 0.2 0.037 13.3 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCD25340.1 - 0.044 13.0 0.6 0.47 9.6 0.0 2.3 2 1 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 CCD25340.1 - 0.06 13.9 0.1 0.23 12.0 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CCD25340.1 - 0.077 12.9 0.5 0.27 11.1 0.2 1.9 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acyltransferase PF01553.21 CCD25341.1 - 4.8e-31 107.2 0.0 7.2e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF5402 PF17393.2 CCD25341.1 - 0.1 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5402) DNA_pol_phi PF04931.13 CCD25342.1 - 0.005 15.0 26.1 0.0067 14.6 26.1 1.1 1 0 0 1 1 1 1 DNA polymerase phi Nop14 PF04147.12 CCD25342.1 - 0.014 13.6 21.5 0.022 13.0 21.5 1.4 1 0 0 1 1 1 0 Nop14-like family CNDH2_C PF16858.5 CCD25342.1 - 0.063 13.2 14.7 0.099 12.5 14.7 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF3340 PF11818.8 CCD25342.1 - 0.31 11.2 25.2 0.82 9.8 25.2 1.6 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Hamartin PF04388.12 CCD25342.1 - 3.5 6.2 20.6 5.4 5.5 20.6 1.3 1 0 0 1 1 1 0 Hamartin protein Usp PF00582.26 CCD25342.1 - 7.1 7.1 8.7 18 5.9 0.0 2.4 2 0 0 2 2 2 0 Universal stress protein family RRN3 PF05327.11 CCD25342.1 - 9.2 4.7 16.7 15 4.0 16.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PTPA PF03095.15 CCD25343.1 - 3e-105 352.0 0.0 3.7e-105 351.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein KCNQ2_u3 PF16642.5 CCD25343.1 - 3.4 8.7 8.0 5.2 8.1 5.7 2.1 1 1 1 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 S-methyl_trans PF02574.16 CCD25344.1 - 1.6e-60 205.2 0.0 1.9e-60 205.0 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase DUF4874 PF16173.5 CCD25344.1 - 0.0069 16.1 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4874) zf-primase PF09329.11 CCD25347.1 - 1.2e-11 44.2 0.2 2.3e-11 43.3 0.2 1.5 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.25 CCD25347.1 - 0.0087 16.0 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF5088 PF17008.5 CCD25347.1 - 0.033 13.9 0.2 0.033 13.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5088) Csm1_N PF18504.1 CCD25348.1 - 0.013 15.8 0.8 0.013 15.8 0.8 21.0 10 7 9 22 22 22 0 Csm1 N-terminal domain LINES_C PF14695.6 CCD25348.1 - 0.15 11.5 6.1 8.4 5.9 0.1 4.9 3 0 0 3 3 3 0 Lines C-terminus DUF3945 PF13101.6 CCD25348.1 - 0.16 11.7 6.1 8 6.3 0.1 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3945) DcpS_C PF11969.8 CCD25348.1 - 3.9 8.0 12.0 3.5 8.1 0.5 4.7 3 0 0 3 3 3 0 Scavenger mRNA decapping enzyme C-term binding ubiquitin PF00240.23 CCD25349.1 - 5.3e-33 112.6 0.5 8.3e-33 112.0 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CCD25349.1 - 2e-30 104.4 10.4 2e-30 104.4 10.4 1.7 2 0 0 2 2 2 1 Ribosomal L40e family Rad60-SLD PF11976.8 CCD25349.1 - 2.5e-14 52.9 0.4 3.9e-14 52.2 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CCD25349.1 - 5.8e-05 23.5 0.2 0.0002 21.7 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CCD25349.1 - 0.0062 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CCD25349.1 - 0.0064 16.8 0.1 0.01 16.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CCD25349.1 - 0.011 15.9 0.1 0.024 14.8 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CCD25349.1 - 0.047 14.2 0.1 0.064 13.8 0.1 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Response_reg PF00072.24 CCD25350.1 - 5.7e-28 97.3 0.6 1.6e-27 95.9 0.4 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 CCD25350.1 - 8.6e-27 93.9 0.4 2.9e-20 72.9 0.1 2.7 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 CCD25350.1 - 2.1e-11 43.7 1.1 6.3e-11 42.2 0.2 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain SR-25 PF10500.9 CCD25350.1 - 0.00054 19.6 7.8 0.00054 19.6 7.8 3.3 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein HAMP PF00672.25 CCD25350.1 - 0.0011 19.4 0.2 0.66 10.4 0.0 2.5 2 0 0 2 2 2 2 HAMP domain SelP_N PF04592.14 CCD25350.1 - 8.4 5.7 21.3 0.14 11.5 13.4 2.0 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Pantoate_ligase PF02569.15 CCD25351.1 - 1.9e-90 302.7 0.0 2.2e-90 302.5 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Ndc80_HEC PF03801.13 CCD25352.1 - 1.7e-46 157.6 1.7 1.7e-46 157.6 1.7 3.0 3 0 0 3 3 3 1 HEC/Ndc80p family DUF5595 PF18077.1 CCD25352.1 - 1.1e-11 44.7 3.2 1.1e-11 44.7 3.2 5.9 5 0 0 5 5 5 2 Domain of unknown function (DUF5595) Val_tRNA-synt_C PF10458.9 CCD25352.1 - 0.25 11.7 7.1 0.14 12.4 2.0 3.2 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm ERCC3_RAD25_C PF16203.5 CCD25354.1 - 2.9e-125 416.5 0.3 2.9e-125 416.5 0.3 2.1 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CCD25354.1 - 5.5e-35 120.3 0.0 1.3e-34 119.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD25354.1 - 3.5e-16 59.7 2.7 5e-16 59.2 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCD25354.1 - 5.4e-12 46.0 1.7 1.5e-11 44.6 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CCD25354.1 - 1.7e-09 36.9 0.1 2.3e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 CCD25354.1 - 3.3e-05 23.7 0.0 8.3e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.6 CCD25354.1 - 0.04 13.3 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Abhydrolase_6 PF12697.7 CCD25355.1 - 3.7e-12 47.3 0.0 6.6e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CCD25355.1 - 1.5e-05 24.8 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 CCD25355.1 - 7.6e-05 22.5 0.1 0.0011 18.7 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCD25355.1 - 9.5e-05 21.8 0.0 0.00027 20.3 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CCD25355.1 - 0.05 13.3 0.1 0.11 12.2 0.1 1.7 1 1 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 CCD25355.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Whi5 PF08528.11 CCD25356.1 - 5.2e-09 35.5 0.3 9.4e-09 34.7 0.3 1.5 1 0 0 1 1 1 1 Whi5 like SR-25 PF10500.9 CCD25356.1 - 1.5 8.4 40.5 1.2 8.7 13.5 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein LIM PF00412.22 CCD25357.1 - 8.2e-06 26.0 21.4 8.2e-06 26.0 10.2 3.7 3 1 0 3 3 3 2 LIM domain DUF3336 PF11815.8 CCD25358.1 - 9.9e-32 109.5 3.8 9.9e-32 109.5 3.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CCD25358.1 - 2.4e-25 89.9 0.0 4.4e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_1 PF00515.28 CCD25359.1 - 9e-10 38.0 4.7 0.0012 18.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCD25359.1 - 1.4e-09 37.3 3.2 0.00056 19.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CCD25359.1 - 1.4e-05 25.3 0.2 0.0073 16.6 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat F-box PF00646.33 CCD25359.1 - 2.8e-05 23.9 0.0 8.9e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 F-box domain TPR_8 PF13181.6 CCD25359.1 - 0.00031 20.7 4.9 0.00096 19.2 0.1 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat F-box-like PF12937.7 CCD25359.1 - 0.0013 18.5 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 CCD25359.1 - 0.0021 18.0 0.2 1.5 9.0 0.0 4.0 3 0 0 3 3 3 1 Leucine Rich repeat TPR_7 PF13176.6 CCD25359.1 - 0.0036 17.2 0.8 0.9 9.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat LRR_4 PF12799.7 CCD25359.1 - 0.0048 17.3 27.6 0.028 14.8 1.2 7.3 5 3 3 8 8 8 2 Leucine Rich repeats (2 copies) ANAPC3 PF12895.7 CCD25359.1 - 0.0083 16.3 3.9 1 9.6 0.8 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CCD25359.1 - 0.15 11.8 0.8 2.8 7.7 0.1 2.7 2 0 0 2 2 2 0 TPR repeat TPR_6 PF13174.6 CCD25359.1 - 0.22 12.3 0.4 4.7 8.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_1 PF00560.33 CCD25359.1 - 3.6 8.5 14.3 18 6.4 0.6 6.2 6 1 0 6 6 5 0 Leucine Rich Repeat Zip PF02535.22 CCD25360.1 - 8.7e-47 160.0 10.1 6.8e-28 97.9 3.1 2.4 2 1 0 2 2 2 2 ZIP Zinc transporter Jagunal PF07086.12 CCD25360.1 - 0.16 12.1 4.6 0.25 11.4 0.3 2.5 2 0 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis Reticulon PF02453.17 CCD25360.1 - 0.77 9.7 11.7 2.9 7.8 0.3 3.8 5 0 0 5 5 5 0 Reticulon U3_snoRNA_assoc PF08297.11 CCD25361.1 - 1.5e-16 60.9 4.7 1.6e-16 60.8 4.7 1.0 1 0 0 1 1 1 1 U3 snoRNA associated Oxidored_molyb PF00174.19 CCD25361.1 - 0.046 13.3 0.0 0.056 13.1 0.0 1.1 1 0 0 1 1 1 0 Oxidoreductase molybdopterin binding domain Kin17_mid PF10357.9 CCD25362.1 - 1.1e-41 141.7 9.4 1.1e-41 141.7 9.4 2.3 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 CCD25362.1 - 7.2e-07 29.3 4.2 2.8e-06 27.5 4.2 2.1 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCD25362.1 - 1.6e-05 25.1 2.8 5.7e-05 23.4 2.8 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CCD25362.1 - 0.0024 18.2 3.5 0.008 16.5 0.5 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CCD25362.1 - 0.025 15.4 1.1 0.09 13.7 1.1 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger DUF640 PF04852.12 CCD25362.1 - 0.047 13.9 0.3 0.44 10.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF640) RL PF17797.1 CCD25362.1 - 0.069 13.1 0.3 0.23 11.4 0.3 1.9 1 0 0 1 1 1 0 RL domain zf-C2H2 PF00096.26 CCD25362.1 - 0.13 12.8 2.4 0.31 11.6 2.4 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-DBF PF07535.12 CCD25362.1 - 0.82 9.8 5.3 3.2 7.9 0.5 2.6 2 0 0 2 2 2 0 DBF zinc finger GTP_EFTU PF00009.27 CCD25363.1 - 7.1e-11 42.0 0.0 2.5e-10 40.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CCD25363.1 - 1.1e-06 28.1 0.6 2.4e-06 27.1 0.6 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCD25363.1 - 9.2e-05 22.5 0.4 0.00043 20.3 0.4 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 CCD25363.1 - 0.0022 18.1 0.1 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arf PF00025.21 CCD25363.1 - 0.012 15.1 0.8 2.5 7.5 0.0 2.7 2 0 0 2 2 2 0 ADP-ribosylation factor family RNA_helicase PF00910.22 CCD25363.1 - 0.042 14.2 0.5 1.2 9.5 0.2 3.0 2 1 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 CCD25363.1 - 0.064 13.3 0.2 0.3 11.1 0.2 2.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CCD25363.1 - 0.08 12.7 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thymidylat_synt PF00303.19 CCD25364.1 - 3.2e-112 374.0 0.0 3.7e-112 373.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Shugoshin_N PF07558.11 CCD25365.1 - 5.5e-14 51.7 11.4 5.5e-14 51.7 11.4 3.2 3 0 0 3 3 3 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 CCD25365.1 - 2.4e-09 36.8 5.9 2.4e-09 36.8 5.9 2.1 2 0 0 2 2 2 1 Shugoshin C terminus Cnn_1N PF07989.11 CCD25365.1 - 0.0083 16.3 5.5 0.0083 16.3 5.5 3.8 3 0 0 3 3 3 1 Centrosomin N-terminal motif 1 CHZ PF09649.10 CCD25365.1 - 0.014 14.8 0.4 0.014 14.8 0.4 2.4 3 0 0 3 3 3 0 Histone chaperone domain CHZ TSC22 PF01166.18 CCD25365.1 - 0.016 15.5 4.4 0.016 15.5 4.4 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family Brix PF04427.18 CCD25366.1 - 2.1e-38 132.4 0.5 3e-38 131.9 0.5 1.2 1 0 0 1 1 1 1 Brix domain RabGAP-TBC PF00566.18 CCD25367.1 - 2.3e-51 174.5 5.6 3.7e-51 173.8 4.4 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Hyphal_reg_CWP PF11765.8 CCD25368.1 - 4.2e-27 94.9 18.9 7.5e-27 94.1 18.9 1.3 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Vps5 PF09325.10 CCD25369.1 - 3.5e-65 219.8 12.5 3.5e-65 219.8 12.5 1.6 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 CCD25369.1 - 7.2e-21 74.3 0.2 2.7e-20 72.4 0.1 2.1 2 0 0 2 2 2 1 PX domain CPSase_L_D3 PF02787.19 CCD25369.1 - 0.05 14.0 0.1 0.21 12.0 0.1 2.1 1 1 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain VEFS-Box PF09733.9 CCD25369.1 - 0.47 10.2 5.5 0.64 9.8 1.7 2.5 2 0 0 2 2 2 0 VEFS-Box of polycomb protein Presenilin PF01080.17 CCD25369.1 - 1 8.1 3.0 1.5 7.5 3.0 1.2 1 0 0 1 1 1 0 Presenilin Alg6_Alg8 PF03155.15 CCD25370.1 - 1.8e-169 564.8 34.6 2.2e-169 564.5 34.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF5436 PF17504.2 CCD25370.1 - 0.026 14.8 0.4 0.12 12.7 0.4 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5436) GT87 PF09594.10 CCD25370.1 - 4.5 6.9 12.4 0.2 11.3 6.4 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 87 Cytochrom_C1 PF02167.15 CCD25372.1 - 1.7e-95 318.9 0.0 2.1e-95 318.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CCD25372.1 - 0.00073 19.8 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CCD25372.1 - 0.0066 17.6 0.5 0.026 15.6 0.2 2.1 3 1 0 3 3 3 1 Cytochrome c PHD PF00628.29 CCD25373.1 - 3e-06 27.0 6.9 5.1e-06 26.3 6.9 1.4 1 0 0 1 1 1 1 PHD-finger Pkinase PF00069.25 CCD25375.1 - 5.9e-57 193.0 0.1 7e-57 192.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25375.1 - 9.6e-17 61.1 0.1 1.5e-16 60.5 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCD25375.1 - 6.9e-08 32.7 0.0 1.9e-07 31.3 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CCD25375.1 - 0.0011 18.6 0.1 0.0019 17.8 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase AcetylCoA_hydro PF02550.15 CCD25375.1 - 0.088 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain Pkinase_fungal PF17667.1 CCD25375.1 - 0.16 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Vma12 PF11712.8 CCD25376.1 - 0.023 14.8 0.5 0.031 14.4 0.0 1.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RTA1 PF04479.13 CCD25377.1 - 3.3e-75 252.3 13.1 4.8e-75 251.7 13.1 1.2 1 0 0 1 1 1 1 RTA1 like protein PhrC_PhrF PF11131.8 CCD25377.1 - 0.15 11.7 1.3 23 4.7 0.1 3.5 3 0 0 3 3 3 0 Rap-phr extracellular signalling Nro1 PF12753.7 CCD25378.1 - 1.2e-139 465.8 21.3 1.4e-139 465.6 21.3 1.0 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 FAST_1 PF06743.15 CCD25378.1 - 0.00011 22.1 0.4 0.00033 20.5 0.2 1.8 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 1 TPR_19 PF14559.6 CCD25378.1 - 0.024 15.2 1.8 2.5 8.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-AN1 PF01428.16 CCD25379.1 - 1.1e-09 38.3 5.4 2.1e-09 37.3 5.4 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger DUF612 PF04747.12 CCD25379.1 - 0.0042 16.3 5.0 0.0042 16.3 5.0 1.4 2 0 0 2 2 2 1 Protein of unknown function, DUF612 C5HCH PF17982.1 CCD25379.1 - 0.046 13.9 5.3 0.099 12.8 5.3 1.6 1 0 0 1 1 1 0 NSD Cys-His rich domain Flavoprotein PF02441.19 CCD25380.1 - 1.9e-50 170.7 0.7 2.8e-50 170.1 0.1 1.6 2 0 0 2 2 2 1 Flavoprotein Nop14 PF04147.12 CCD25380.1 - 1.9 6.6 26.6 3.2 5.9 26.6 1.3 1 0 0 1 1 1 0 Nop14-like family SGT1 PF07093.11 CCD25380.1 - 3.4 6.0 12.2 5.9 5.2 12.2 1.3 1 0 0 1 1 1 0 SGT1 protein MAP65_ASE1 PF03999.12 CCD25381.1 - 1e-98 331.6 60.1 1e-98 331.6 60.1 2.4 2 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) RVT_1 PF00078.27 CCD25382.1 - 1.6e-32 112.8 0.2 4.1e-32 111.5 0.2 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CCD25382.1 - 6.1e-31 106.4 0.0 1.5e-30 105.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCD25382.1 - 1e-30 106.1 0.0 2.4e-30 104.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CCD25382.1 - 7.7e-18 64.4 1.7 1.7e-17 63.3 0.6 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CCD25382.1 - 7.1e-14 52.0 0.0 1.9e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 CCD25382.1 - 8.7e-10 39.0 0.0 2.2e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CCD25382.1 - 2.6e-09 37.6 0.0 6.2e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CCD25382.1 - 3.4e-06 26.9 0.0 6.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CCD25382.1 - 0.0025 18.1 0.5 0.027 14.8 0.0 2.7 3 0 0 3 3 3 1 Retroviral aspartyl protease zf-H2C2 PF09337.10 CCD25382.1 - 0.0057 16.9 0.4 0.042 14.1 0.0 2.5 2 0 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 CCD25382.1 - 0.053 13.3 0.2 0.88 9.4 0.0 2.8 2 0 0 2 2 2 0 Integrase core domain DUF2312 PF10073.9 CCD25382.1 - 0.096 12.3 0.1 0.31 10.7 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) zf-CCHC PF00098.23 CCD25383.1 - 1.1e-05 25.3 2.6 1.8e-05 24.6 2.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 CCD25383.1 - 0.0051 16.5 1.7 0.013 15.2 1.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CCD25383.1 - 0.067 13.2 1.8 0.11 12.5 1.8 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF2340 PF10209.9 CCD25384.1 - 1.3e-51 174.0 4.9 1.6e-51 173.8 4.9 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) DUF676 PF05057.14 CCD25385.1 - 5e-44 150.4 0.0 8.1e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CCD25385.1 - 7.8e-05 22.5 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Glyco_hydro_64 PF16483.5 CCD25385.1 - 0.045 13.0 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta-1,3-glucanase Sld7_N PF18636.1 CCD25386.1 - 5.9e-44 149.4 0.3 9.2e-44 148.8 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial morphogenesis protein SLD7 N-terminal domain Sld7_C PF18596.1 CCD25386.1 - 2.6e-14 53.1 0.0 5.4e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Sld7 C-terminal domain XRN_M PF17846.1 CCD25387.1 - 6.8e-136 453.7 9.9 1.5e-101 340.5 0.3 2.8 2 1 1 3 3 3 2 Xrn1 helical domain XRN_N PF03159.18 CCD25387.1 - 2.4e-98 328.4 0.0 2.4e-98 328.4 0.0 2.6 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus STD1 PF17235.2 CCD25388.1 - 1.1e-74 250.6 0.2 1.1e-74 250.6 0.2 2.8 2 1 2 4 4 4 1 STD1/MTH1 DEAD PF00270.29 CCD25389.1 - 8.1e-36 123.4 0.1 1.2e-35 122.8 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD25389.1 - 1.1e-27 96.5 0.0 2.8e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD25389.1 - 1.2e-06 28.7 0.0 2.8e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CCD25389.1 - 0.048 13.4 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CCD25389.1 - 0.12 12.7 0.2 0.46 10.8 0.2 2.0 1 1 0 1 1 1 0 AAA domain Tom6 PF17112.5 CCD25390.1 - 1.7e-26 91.4 1.1 2.4e-26 91.0 1.1 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal Herpes_LMP1 PF05297.11 CCD25391.1 - 0.36 10.0 2.5 0.17 11.0 0.5 1.5 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Kri1_C PF12936.7 CCD25392.1 - 0.087 13.0 1.1 0.55 10.4 1.1 2.3 1 1 0 1 1 1 0 KRI1-like family C-terminal CUE PF02845.16 CCD25393.1 - 3.9e-10 39.2 0.0 7.2e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 CUE domain HAGH_C PF16123.5 CCD25394.1 - 2e-18 66.7 0.1 3.4e-18 65.9 0.1 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CCD25394.1 - 1.9e-07 31.3 0.2 2.4e-06 27.7 0.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CCD25394.1 - 0.00099 18.7 0.1 0.0017 17.9 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Gp-FAR-1 PF05823.12 CCD25394.1 - 0.13 12.6 0.1 1.9 8.8 0.1 2.1 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CK_II_beta PF01214.18 CCD25395.1 - 5.5e-73 244.7 0.1 6.6e-73 244.4 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RecG_N PF17190.4 CCD25395.1 - 0.15 12.8 1.0 0.35 11.6 0.3 1.9 2 0 0 2 2 2 0 RecG N-terminal helical domain Hira PF07569.11 CCD25396.1 - 1.2e-82 276.9 0.2 1.5e-81 273.3 0.1 2.7 2 1 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 CCD25396.1 - 0.013 16.4 0.3 14 6.8 0.0 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat Pet20 PF08692.10 CCD25396.1 - 5 7.8 9.9 0.23 12.2 3.4 2.1 2 0 0 2 2 2 0 Mitochondrial protein Pet20 FAD_binding_6 PF00970.24 CCD25397.1 - 4.8e-06 26.8 0.0 0.00013 22.2 0.0 2.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Syntaxin_2 PF14523.6 CCD25398.1 - 9.3e-21 74.1 13.0 9.3e-21 74.1 13.0 2.7 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 CCD25398.1 - 4.3e-14 52.2 0.1 1.1e-13 51.0 0.1 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CCD25398.1 - 3.2e-05 23.7 20.6 0.00015 21.5 20.6 1.9 1 1 0 1 1 1 1 Syntaxin MtrB PF05440.12 CCD25398.1 - 0.013 15.9 1.3 1.4 9.4 0.0 3.1 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B Spectrin_like PF18373.1 CCD25398.1 - 0.019 15.0 0.5 0.019 15.0 0.5 3.1 3 0 0 3 3 3 0 Spectrin like domain T3SSipB PF16535.5 CCD25398.1 - 0.039 14.4 1.3 0.039 14.4 1.3 2.4 2 1 1 3 3 3 0 Type III cell invasion protein SipB V-SNARE PF05008.15 CCD25398.1 - 0.14 12.5 12.1 0.22 11.9 2.5 3.6 2 2 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus betaPIX_CC PF16523.5 CCD25398.1 - 0.28 11.0 0.1 0.28 11.0 0.1 3.3 3 1 1 4 4 4 0 betaPIX coiled coil DUF1664 PF07889.12 CCD25398.1 - 0.41 10.7 16.7 0.7 9.9 2.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Synaptobrevin PF00957.21 CCD25398.1 - 1.1 9.1 8.9 0.092 12.6 2.5 2.5 2 1 1 3 3 3 0 Synaptobrevin MCPsignal PF00015.21 CCD25398.1 - 1.2 8.9 9.8 1.3 8.8 1.3 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4162 PF13732.6 CCD25398.1 - 1.3 9.8 7.9 14 6.5 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4162) DUF4988 PF16378.5 CCD25398.1 - 3.9 7.1 18.1 0.83 9.3 2.3 3.5 3 1 1 4 4 4 0 Domain of unknown function CEP209_CC5 PF16574.5 CCD25398.1 - 5.5 7.2 20.8 14 5.8 13.1 3.4 1 1 2 3 3 3 0 Coiled-coil region of centrosome protein CE290 zf-CCHC_2 PF13696.6 CCD25399.1 - 0.062 13.1 3.3 0.12 12.2 3.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Sec10 PF07393.11 CCD25400.1 - 0.032 12.7 1.2 1.9 6.8 0.1 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec10 OHCU_decarbox PF09349.10 CCD25400.1 - 0.17 12.4 0.5 0.38 11.2 0.4 1.9 1 1 0 1 1 1 0 OHCU decarboxylase zf-C2H2 PF00096.26 CCD25400.1 - 1.3 9.6 17.5 2.2 8.9 3.3 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type UNC45-central PF11701.8 CCD25401.1 - 1.4e-23 83.6 0.1 2.1e-22 79.7 0.0 3.1 3 1 0 3 3 3 1 Myosin-binding striated muscle assembly central ING PF12998.7 CCD25401.1 - 6.4 7.4 10.7 0.062 13.9 1.0 2.6 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Ank_2 PF12796.7 CCD25402.1 - 6.4e-26 90.8 0.5 6.7e-13 49.0 0.1 3.3 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CCD25402.1 - 3.7e-21 73.0 2.0 0.00039 20.6 0.0 6.4 5 1 1 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 CCD25402.1 - 2.6e-20 72.2 2.0 1.4e-07 31.7 0.0 5.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCD25402.1 - 1.4e-19 70.1 2.8 2.7e-06 27.8 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CCD25402.1 - 1.5e-16 60.0 1.4 0.00038 20.8 0.0 6.1 5 0 0 5 5 5 5 Ankyrin repeat XPG_N PF00752.17 CCD25403.1 - 4.6e-29 100.9 0.0 1.3e-28 99.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CCD25403.1 - 6.1e-20 71.4 0.0 2.8e-19 69.2 0.0 2.2 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 CCD25403.1 - 0.0026 17.3 0.1 0.013 15.0 0.0 2.1 2 0 0 2 2 2 1 XPG domain containing 5_3_exonuc PF01367.20 CCD25403.1 - 0.0034 17.9 0.0 0.013 16.0 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_8 PF13181.6 CCD25403.1 - 0.048 13.9 0.0 0.38 11.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat HHH_2 PF12826.7 CCD25403.1 - 0.056 13.5 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif MULE PF10551.9 CCD25404.1 - 0.0023 18.3 0.0 0.0059 17.0 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain UBA_e1_thiolCys PF10585.9 CCD25404.1 - 0.04 13.9 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site Flavodoxin_NdrI PF07972.11 CCD25404.1 - 0.17 12.1 1.4 2.6 8.2 0.0 3.1 3 1 1 4 4 4 0 NrdI Flavodoxin like TetR_C_35 PF18556.1 CCD25404.1 - 0.18 11.9 0.0 0.55 10.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain HLH PF00010.26 CCD25405.1 - 2.9e-19 68.8 0.0 9.9e-19 67.1 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain CssAB PF16831.5 CCD25405.1 - 0.089 13.2 0.4 0.29 11.5 0.2 2.0 2 1 0 2 2 2 0 CS6 fimbrial subunits A and B, Coli surface antigen 6 PalH PF08733.10 CCD25408.1 - 4.2e-101 338.3 24.2 5.4e-101 337.9 24.2 1.1 1 0 0 1 1 1 1 PalH/RIM21 DUF4386 PF14329.6 CCD25408.1 - 0.11 12.4 2.2 0.47 10.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) Secretin_N_2 PF07655.13 CCD25408.1 - 0.71 10.5 15.5 0.038 14.5 4.1 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain DUF4834 PF16118.5 CCD25408.1 - 1.7 9.7 6.1 1.7 9.6 0.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) bZIP_1 PF00170.21 CCD25409.1 - 8.2e-11 41.8 9.0 8.2e-11 41.8 9.0 2.0 2 0 0 2 2 2 1 bZIP transcription factor HALZ PF02183.18 CCD25409.1 - 0.16 12.3 2.1 0.24 11.6 0.6 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 CCD25409.1 - 0.2 11.9 6.0 0.28 11.4 2.9 2.7 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 TPR_1 PF00515.28 CCD25410.1 - 9.9e-47 154.9 21.3 4.2e-07 29.5 1.8 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 CCD25410.1 - 8.6e-39 128.5 21.4 1.8e-06 27.6 1.2 9.5 8 1 1 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 CCD25410.1 - 1.3e-37 127.4 15.8 1.2e-18 66.7 4.5 3.0 3 0 0 3 3 3 2 STI1 domain TPR_11 PF13414.6 CCD25410.1 - 2.9e-25 87.7 26.6 4.9e-05 22.9 0.0 8.8 8 1 1 9 9 9 7 TPR repeat TPR_8 PF13181.6 CCD25410.1 - 4.1e-22 76.5 22.9 9.5e-05 22.3 0.5 9.2 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 CCD25410.1 - 4.8e-21 74.8 10.9 6.1e-08 32.8 0.2 6.4 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 CCD25410.1 - 7.2e-19 68.2 2.8 0.00065 20.3 0.0 6.7 3 3 2 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.6 CCD25410.1 - 4.7e-18 64.3 1.6 0.76 10.8 0.0 8.8 5 3 4 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCD25410.1 - 4.5e-12 45.5 10.8 0.061 13.7 0.0 7.4 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CCD25410.1 - 8.7e-12 45.4 16.3 0.0081 16.7 0.2 6.6 5 2 1 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 CCD25410.1 - 5.6e-11 41.7 6.1 0.003 17.5 0.0 7.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 CCD25410.1 - 4.4e-10 39.1 6.8 0.093 12.6 0.5 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 CCD25410.1 - 1.8e-06 28.0 0.0 0.0058 16.7 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CCD25410.1 - 2.4e-05 23.9 2.5 0.82 9.0 0.0 4.5 3 2 0 4 4 4 1 MalT-like TPR region TPR_6 PF13174.6 CCD25410.1 - 0.0002 21.8 17.0 5.7 7.8 0.0 7.8 8 0 0 8 8 7 1 Tetratricopeptide repeat DUF3808 PF10300.9 CCD25410.1 - 0.00048 19.0 2.1 0.0013 17.5 0.1 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) ANAPC3 PF12895.7 CCD25410.1 - 0.0019 18.4 14.0 1.3 9.3 0.1 5.1 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 CCD25410.1 - 0.0076 16.6 0.2 0.032 14.5 0.3 5.1 4 3 3 7 7 5 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 CCD25410.1 - 0.02 14.3 9.6 11 5.5 0.1 6.5 7 0 0 7 7 7 0 SHNi-TPR Sel1 PF08238.12 CCD25410.1 - 0.064 14.0 1.2 6.2 7.6 0.0 3.7 3 0 0 3 3 3 0 Sel1 repeat BTAD PF03704.17 CCD25410.1 - 0.17 12.4 7.5 15 6.0 0.0 5.1 4 2 2 6 6 6 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 CCD25410.1 - 0.19 11.8 4.4 32 4.7 0.5 4.5 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DnaI_N PF07319.11 CCD25410.1 - 0.2 12.3 12.2 4.1 8.1 0.2 4.8 3 2 2 5 5 5 0 Primosomal protein DnaI N-terminus PPR_2 PF13041.6 CCD25410.1 - 0.22 11.7 1.8 10 6.4 0.0 4.1 5 0 0 5 5 4 0 PPR repeat family PPR PF01535.20 CCD25410.1 - 0.28 11.5 2.2 1.3e+02 3.1 0.0 5.1 7 0 0 7 7 5 0 PPR repeat RPN7 PF10602.9 CCD25410.1 - 0.6 9.8 22.2 0.44 10.2 0.4 6.3 3 2 4 7 7 7 0 26S proteasome subunit RPN7 MAS20 PF02064.15 CCD25410.1 - 1.1 9.3 0.0 1.1 9.3 0.0 4.8 4 1 1 5 5 4 0 MAS20 protein import receptor WD40_like PF17005.5 CCD25411.1 - 1e-07 31.6 0.3 0.13 11.6 0.0 3.1 3 0 0 3 3 3 3 WD40-like domain ANAPC4_WD40 PF12894.7 CCD25411.1 - 3.6e-06 27.2 0.5 0.51 10.7 0.0 4.6 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCD25411.1 - 3.9e-06 27.5 0.2 0.00081 20.2 0.0 3.4 2 0 0 2 2 2 1 WD domain, G-beta repeat eIF2A PF08662.11 CCD25411.1 - 0.02 14.8 0.1 0.034 14.0 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A SIR2 PF02146.17 CCD25412.1 - 3e-31 108.7 0.0 2.9e-16 59.9 0.0 2.3 2 0 0 2 2 2 2 Sir2 family Med21 PF11221.8 CCD25412.1 - 0.16 12.2 2.3 0.65 10.3 0.1 2.4 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Allantoicase PF03561.15 CCD25414.1 - 1.6e-44 151.4 1.7 6.1e-40 136.5 0.1 2.1 2 0 0 2 2 2 2 Allantoicase repeat Transp_cyt_pur PF02133.15 CCD25415.1 - 8.2e-174 578.5 40.8 1e-173 578.2 40.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PNKP_ligase PF16542.5 CCD25415.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain Amidohydro_1 PF01979.20 CCD25416.1 - 2.3e-36 125.8 0.0 3e-35 122.2 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CCD25416.1 - 3.8e-09 36.5 0.0 0.00022 20.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family FAM83 PF07894.12 CCD25416.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 FAM83 A-H Asp_Glu_race PF01177.22 CCD25417.1 - 5.9e-08 32.8 0.0 6.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Malate_synthase PF01274.22 CCD25418.1 - 1.3e-216 719.9 0.0 1.6e-216 719.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 CCD25418.1 - 0.032 13.4 0.0 0.062 12.4 0.0 1.5 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family DUF1870 PF08965.10 CCD25418.1 - 0.1 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) Ureidogly_lyase PF04115.12 CCD25419.1 - 1.1e-47 162.2 0.0 1.2e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase Cpn10 PF00166.21 CCD25420.1 - 9.3e-28 96.1 0.2 1e-27 96.0 0.2 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF4537 PF15057.6 CCD25421.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) SH3_15 PF18346.1 CCD25421.1 - 0.15 12.4 0.1 0.91 9.9 0.1 2.1 1 1 0 1 1 1 0 Mind bomb SH3 repeat domain Acetyltransf_1 PF00583.25 CCD25423.1 - 1.4e-09 38.2 0.0 2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCD25423.1 - 5.5e-07 29.6 0.2 7.8e-07 29.1 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCD25423.1 - 2.4e-05 24.2 0.1 4.5e-05 23.3 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 CCD25423.1 - 0.00069 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCD25423.1 - 0.00087 19.7 0.0 0.0014 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CCD25423.1 - 0.0039 16.7 0.2 0.0045 16.5 0.2 1.3 1 1 0 1 1 1 1 Putative acetyl-transferase HTH_16 PF12645.7 CCD25423.1 - 0.03 14.4 0.6 0.086 12.9 0.3 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Acetyltransf_CG PF14542.6 CCD25423.1 - 0.048 13.8 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Metallophos_2 PF12850.7 CCD25424.1 - 5.2e-10 39.8 0.0 7.5e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain tRNA-synt_2b PF00587.25 CCD25425.1 - 2.5e-18 66.7 0.0 4e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) RasGAP_C PF03836.15 CCD25425.1 - 0.00016 21.8 1.3 0.00029 21.0 1.3 1.4 1 0 0 1 1 1 1 RasGAP C-terminus Seryl_tRNA_N PF02403.22 CCD25425.1 - 0.00044 20.5 4.0 0.00081 19.6 4.0 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain 4HB_MCP_1 PF12729.7 CCD25425.1 - 0.00096 18.7 1.4 0.0017 17.9 1.4 1.3 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction EzrA PF06160.12 CCD25425.1 - 0.0018 16.6 2.7 0.0026 16.0 2.7 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA CREPT PF16566.5 CCD25425.1 - 0.0022 18.2 1.2 0.0052 17.0 1.2 1.6 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour FmiP_Thoc5 PF09766.9 CCD25425.1 - 0.0022 17.3 3.6 0.0036 16.7 3.6 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 HSBP1 PF06825.12 CCD25425.1 - 0.0068 16.2 0.7 0.023 14.5 0.3 2.1 2 0 0 2 2 2 1 Heat shock factor binding protein 1 FH2 PF02181.23 CCD25425.1 - 0.0084 15.3 2.2 0.013 14.6 2.2 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Baculo_PEP_C PF04513.12 CCD25425.1 - 0.0094 16.0 1.6 0.0094 16.0 1.6 1.9 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Occludin_ELL PF07303.13 CCD25425.1 - 0.026 15.2 0.4 0.055 14.2 0.4 1.5 1 0 0 1 1 1 0 Occludin homology domain RsgA_GTPase PF03193.16 CCD25425.1 - 0.029 14.3 0.3 0.053 13.4 0.3 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF724 PF05266.14 CCD25425.1 - 0.037 13.9 7.2 0.076 12.8 7.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) OmpH PF03938.14 CCD25425.1 - 0.046 14.1 2.2 0.32 11.3 1.2 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 CCD25425.1 - 0.054 13.7 3.8 0.13 12.5 3.8 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Cut12 PF11500.8 CCD25425.1 - 0.055 13.4 2.5 0.097 12.6 2.5 1.3 1 0 0 1 1 1 0 Spindle pole body formation-associated protein FliD_N PF02465.18 CCD25425.1 - 0.074 13.8 6.0 0.17 12.6 5.6 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus FapA PF03961.13 CCD25425.1 - 0.076 11.6 2.0 0.11 11.0 2.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A LMBR1 PF04791.16 CCD25425.1 - 0.13 11.2 0.5 0.17 10.8 0.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Tup_N PF08581.10 CCD25425.1 - 0.16 12.3 3.7 0.23 11.8 2.4 1.9 1 1 1 2 2 2 0 Tup N-terminal tRNA-synt_His PF13393.6 CCD25425.1 - 0.16 11.2 0.0 0.48 9.6 0.0 1.7 2 0 0 2 2 2 0 Histidyl-tRNA synthetase PhaP_Bmeg PF09602.10 CCD25425.1 - 0.22 11.4 6.4 0.17 11.8 4.1 2.0 2 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF745 PF05335.13 CCD25425.1 - 0.27 10.9 1.8 0.42 10.3 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Sec2p PF06428.11 CCD25425.1 - 0.33 11.0 4.1 0.38 10.7 2.5 1.8 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p KxDL PF10241.9 CCD25425.1 - 1.8 8.9 6.3 3.7 7.9 6.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein Ribosomal_L27e PF01777.18 CCD25426.1 - 6.2e-37 125.8 7.6 9.2e-37 125.3 7.6 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CCD25426.1 - 0.00066 19.5 1.6 0.0012 18.7 1.6 1.5 1 0 0 1 1 1 1 KOW motif DAO PF01266.24 CCD25427.1 - 1.5e-66 225.4 0.0 5.2e-66 223.6 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCD25427.1 - 2.2e-05 24.6 0.0 6.6e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CCD25427.1 - 0.00014 21.2 0.2 0.00037 19.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family DUF3439 PF11921.8 CCD25427.1 - 0.00053 19.9 1.0 0.0011 18.9 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) MCRA PF06100.11 CCD25427.1 - 0.0057 15.5 0.0 0.0089 14.9 0.0 1.4 1 0 0 1 1 1 1 MCRA family Sacchrp_dh_NADP PF03435.18 CCD25427.1 - 0.05 13.9 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 CCD25427.1 - 0.061 12.6 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CCD25427.1 - 0.11 11.3 0.3 1.8 7.3 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase CENP-B_dimeris PF09026.10 CCD25427.1 - 1.1 9.7 10.9 3.8 8.0 10.9 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sod_Fe_C PF02777.18 CCD25428.1 - 5.5e-33 113.2 1.9 1.1e-32 112.2 1.9 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CCD25428.1 - 2.4e-26 92.0 0.5 4.9e-26 91.0 0.5 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HHH_2 PF12826.7 CCD25428.1 - 0.0052 16.9 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif FadA PF09403.10 CCD25428.1 - 0.088 13.3 0.6 2 8.9 0.1 2.4 2 0 0 2 2 2 0 Adhesion protein FadA p450 PF00067.22 CCD25429.1 - 6e-99 331.9 0.0 8.2e-99 331.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 LCAT PF02450.15 CCD25430.1 - 4.3e-125 417.9 0.5 6.2e-125 417.4 0.5 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 CCD25430.1 - 0.016 14.7 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 2) DUF1749 PF08538.10 CCD25430.1 - 0.038 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Autophagy_N PF03986.13 CCD25431.1 - 1.6e-39 135.0 0.7 1.6e-39 135.0 0.7 2.2 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 CCD25431.1 - 2.7e-14 52.4 1.1 4.9e-14 51.5 1.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 CCD25431.1 - 5.4e-14 52.5 0.0 1.3e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain VHS PF00790.19 CCD25432.1 - 2.9e-35 121.2 1.2 8.1e-35 119.7 0.0 2.3 2 1 1 3 3 3 1 VHS domain FYVE PF01363.21 CCD25432.1 - 4.4e-19 68.4 3.7 1.3e-18 66.8 3.7 1.8 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 CCD25432.1 - 5e-08 32.3 6.3 0.0001 22.0 2.4 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif STI1 PF17830.1 CCD25432.1 - 0.042 13.8 0.1 0.17 11.9 0.1 2.1 1 0 0 1 1 1 0 STI1 domain zf_C2HC_14 PF18574.1 CCD25432.1 - 2.9 7.8 5.9 5.4 6.9 5.9 1.4 1 0 0 1 1 1 0 C2HC Zing finger domain DUF4488 PF14869.6 CCD25433.1 - 0.083 12.8 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) Cyclin_N PF00134.23 CCD25434.1 - 4.9e-40 136.2 0.6 1.4e-39 134.8 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain SP24 PF16504.5 CCD25434.1 - 0.0013 18.7 0.4 0.0036 17.3 0.4 1.6 1 0 0 1 1 1 1 Putative virion membrane protein of plant and insect virus DUF1053 PF06327.14 CCD25434.1 - 6.2 7.4 8.5 26 5.5 1.4 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) BBP1_C PF15272.6 CCD25435.1 - 1.3e-57 194.7 28.3 1.3e-57 194.7 28.3 3.5 3 1 1 4 4 4 2 Spindle pole body component BBP1, C-terminal BBP1_N PF15271.6 CCD25435.1 - 9.7e-47 159.6 10.2 9.7e-47 159.6 10.2 3.1 2 1 0 2 2 2 1 Spindle pole body component BBP1, Mps2-binding protein VP4_2 PF08935.10 CCD25435.1 - 0.0088 16.6 1.4 0.048 14.2 1.4 2.3 1 0 0 1 1 1 1 Viral protein VP4 subunit Pox_A_type_inc PF04508.12 CCD25435.1 - 0.24 11.3 3.2 0.19 11.7 0.5 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat SAGA-Tad1 PF12767.7 CCD25436.1 - 2.1e-76 256.8 1.0 5.4e-76 255.4 1.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Microtub_bd PF16796.5 CCD25437.1 - 1.7e-11 44.3 1.5 1.7e-11 44.3 1.5 4.4 3 2 0 5 5 5 1 Microtubule binding Fer2 PF00111.27 CCD25438.1 - 1.2e-12 47.6 1.5 1.6e-12 47.2 1.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RabGAP-TBC PF00566.18 CCD25440.1 - 2.2e-47 161.5 0.3 2.2e-47 161.5 0.3 3.9 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Fungal_trans PF04082.18 CCD25441.1 - 1.2e-22 80.2 6.2 3.3e-22 78.8 6.2 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD25441.1 - 2e-07 31.0 18.0 3.5e-07 30.2 18.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 CCD25441.1 - 3.6e-06 27.0 0.1 9e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 Gal4-like dimerisation domain DEAD PF00270.29 CCD25442.1 - 1.1e-21 77.4 0.0 2.1e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.10 CCD25442.1 - 3.8e-21 75.0 0.3 1.7e-20 72.9 0.2 2.0 2 0 0 2 2 2 1 RQC domain Helicase_C PF00271.31 CCD25442.1 - 8.4e-19 68.0 9.7 1.9e-15 57.2 0.0 3.8 5 0 0 5 5 5 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 CCD25442.1 - 7.9e-15 55.3 8.1 7.9e-15 55.3 8.1 2.4 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 CCD25442.1 - 1.3e-06 28.5 0.0 4.3e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 CCD25442.1 - 0.035 13.4 0.2 0.29 10.4 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain Cys_box PF17869.1 CCD25442.1 - 1.3 9.2 9.2 15 5.8 5.6 3.3 2 1 1 3 3 3 0 Anosmin cysteine rich domain WD40 PF00400.32 CCD25443.1 - 2.7e-10 40.6 10.8 0.0022 18.8 0.1 4.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD25443.1 - 0.0028 17.9 4.3 3.7 7.9 0.0 4.7 3 3 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Rhomboid PF01694.22 CCD25445.1 - 2.3e-15 56.9 13.1 3.7e-15 56.2 13.1 1.3 1 0 0 1 1 1 1 Rhomboid family LpxB PF02684.15 CCD25445.1 - 0.049 12.5 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase DUF2075 PF09848.9 CCD25446.1 - 1.5e-103 346.9 0.5 1.9e-103 346.5 0.1 1.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CCD25446.1 - 1.7e-08 34.8 0.3 6.3e-08 33.0 0.0 2.0 1 1 1 2 2 2 1 AAA domain ResIII PF04851.15 CCD25446.1 - 0.00014 22.0 0.0 0.13 12.2 0.1 2.5 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA PF00004.29 CCD25446.1 - 0.00031 21.2 0.0 0.0006 20.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CCD25446.1 - 0.00074 19.6 0.6 0.004 17.2 0.1 2.3 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 CCD25446.1 - 0.0012 18.3 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein AAA_16 PF13191.6 CCD25446.1 - 0.002 18.5 0.0 0.0048 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 CCD25446.1 - 0.005 16.6 0.0 0.055 13.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain Adeno_IVa2 PF02456.15 CCD25446.1 - 0.0058 15.5 0.0 0.0094 14.8 0.0 1.2 1 0 0 1 1 1 1 Adenovirus IVa2 protein PIF1 PF05970.14 CCD25446.1 - 0.0079 15.4 0.0 0.017 14.3 0.0 1.6 1 1 0 1 1 1 1 PIF1-like helicase NACHT PF05729.12 CCD25446.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.6 1 1 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 CCD25446.1 - 0.035 14.5 0.0 0.078 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain VirE PF05272.11 CCD25446.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Virulence-associated protein E NB-ARC PF00931.22 CCD25446.1 - 0.085 12.0 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain YqcI_YcgG PF08892.11 CCD25446.1 - 0.095 12.5 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 YqcI/YcgG family T2SSE PF00437.20 CCD25446.1 - 0.11 11.6 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 CCD25446.1 - 0.11 12.2 1.2 3.7 7.3 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_7 PF12775.7 CCD25446.1 - 0.12 11.9 1.0 0.35 10.4 0.0 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CCD25446.1 - 0.12 12.8 0.0 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 CCD25446.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UAA PF08449.11 CCD25447.1 - 7.9e-28 97.5 11.8 9.2e-28 97.3 11.8 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CCD25447.1 - 1.7e-07 31.5 10.2 1.7e-07 31.5 10.2 2.3 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 CCD25447.1 - 0.0036 16.7 6.5 0.0036 16.7 6.5 1.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family Orf78 PF06024.12 CCD25447.1 - 0.093 13.0 0.3 0.093 13.0 0.3 2.3 2 0 0 2 2 2 0 Orf78 (ac78) BTP PF05232.12 CCD25447.1 - 0.096 12.8 1.1 0.096 12.8 1.1 2.4 2 0 0 2 2 2 0 Chlorhexidine efflux transporter DUF2663 PF10864.8 CCD25447.1 - 0.65 10.4 5.5 0.29 11.6 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) SRP68 PF16969.5 CCD25448.1 - 4.5e-62 210.8 22.3 5.5e-62 210.5 22.3 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 RasGAP_C PF03836.15 CCD25449.1 - 1.1e-26 93.6 6.6 1.1e-26 93.6 6.6 3.1 3 1 0 3 3 3 1 RasGAP C-terminus RasGAP PF00616.19 CCD25449.1 - 1.4e-16 60.9 3.1 1.4e-16 60.9 3.1 2.7 2 1 1 3 3 3 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 CCD25449.1 - 2.4e-13 50.2 1.9 1.8e-12 47.4 0.0 3.3 3 0 0 3 3 3 1 Calponin homology (CH) domain IQ PF00612.27 CCD25449.1 - 3.9e-08 32.4 34.2 0.0047 16.6 0.4 10.2 10 0 0 10 10 10 3 IQ calmodulin-binding motif CH_2 PF06294.11 CCD25449.1 - 0.0036 17.4 0.1 2.3 8.4 0.0 3.8 3 0 0 3 3 3 1 CH-like domain in sperm protein Cbl_N2 PF02761.14 CCD25449.1 - 0.008 16.9 1.3 1.4 9.7 0.1 3.2 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain DUF2316 PF10078.9 CCD25449.1 - 0.088 13.0 2.8 0.28 11.4 0.2 3.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) MIT_C PF16565.5 CCD25449.1 - 0.12 12.3 3.3 1.5 8.8 1.4 3.1 2 0 0 2 2 2 0 Phospholipase D-like domain at C-terminus of MIT NPV_P10 PF05531.12 CCD25449.1 - 0.75 10.3 5.5 13 6.3 0.4 4.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TBCC PF07986.12 CCD25450.1 - 2.7e-06 27.1 3.3 1.3e-05 24.9 3.3 2.2 1 1 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 CCD25450.1 - 0.00098 19.6 1.9 0.00098 19.6 1.9 2.0 1 1 1 2 2 2 1 Tubulin-specific chaperone C N-terminal domain Ank_2 PF12796.7 CCD25451.1 - 9.3e-22 77.4 1.7 8.1e-15 55.2 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCD25451.1 - 3e-15 56.4 0.0 1.3e-10 41.5 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CCD25451.1 - 2.2e-14 53.3 0.1 2.3e-07 30.9 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCD25451.1 - 9.3e-13 47.1 0.0 2.4e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 CCD25451.1 - 3.8e-12 46.1 0.0 6.8e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat eIF-5_eIF-2B PF01873.17 CCD25452.1 - 5.3e-38 129.5 0.9 2.2e-37 127.5 0.1 2.0 2 0 0 2 2 2 1 Domain found in IF2B/IF5 IF2_N PF04760.15 CCD25452.1 - 0.025 14.4 0.7 0.12 12.2 0.0 2.5 3 1 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region TF_Zn_Ribbon PF08271.12 CCD25452.1 - 0.029 13.9 0.2 0.058 12.9 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding BST2 PF16716.5 CCD25452.1 - 0.072 13.7 2.9 1.3 9.6 0.7 2.7 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 PKI PF02827.16 CCD25452.1 - 0.079 13.2 1.8 0.23 11.7 1.8 1.8 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor DUF35_N PF12172.8 CCD25452.1 - 0.11 12.4 0.1 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Pex19 PF04614.12 CCD25452.1 - 0.35 10.6 6.9 2.6 7.8 6.0 2.1 2 0 0 2 2 2 0 Pex19 protein family Arc_trans_TRASH PF08394.10 CCD25452.1 - 3.5 8.1 5.8 29 5.1 1.9 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain Pkinase PF00069.25 CCD25453.1 - 8.6e-31 107.3 0.0 4.5e-23 81.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25453.1 - 2.6e-16 59.7 0.0 1.4e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCD25453.1 - 0.16 11.3 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like TIP49 PF06068.13 CCD25454.1 - 1.9e-155 517.4 1.4 2.4e-155 517.0 1.4 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CCD25454.1 - 1.4e-23 82.8 0.5 4.7e-23 81.1 0.4 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 CCD25454.1 - 7.4e-08 32.9 0.5 0.00012 22.5 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CCD25454.1 - 2.8e-07 30.4 1.3 0.0023 17.7 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 CCD25454.1 - 9.5e-06 25.1 0.2 1.8e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 CCD25454.1 - 7.6e-05 23.2 0.3 0.00024 21.5 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 CCD25454.1 - 0.0024 18.2 0.5 0.024 15.0 0.5 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCD25454.1 - 0.0035 17.6 0.1 0.51 10.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 CCD25454.1 - 0.0087 16.1 0.2 2.6 8.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CCD25454.1 - 0.0087 15.5 1.0 0.17 11.2 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CCD25454.1 - 0.0088 15.6 0.6 0.022 14.3 0.2 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CCD25454.1 - 0.013 15.8 0.1 0.033 14.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CCD25454.1 - 0.062 13.0 0.1 8.2 6.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain DraK_HK_N PF18092.1 CCD25454.1 - 0.082 13.3 0.9 3.1 8.3 0.1 2.7 2 0 0 2 2 2 0 DraK Histidine Kinase N-terminal domain ATP-synt_C PF00137.21 CCD25455.1 - 4.3e-31 107.0 30.5 1.5e-18 66.9 8.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Mis14 PF08641.12 CCD25456.1 - 2.9e-36 124.7 8.0 2.9e-36 124.7 8.0 1.6 2 0 0 2 2 2 1 Kinetochore protein Mis14 like CPDase PF07823.11 CCD25456.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.4 1 1 0 1 1 1 0 Cyclic phosphodiesterase-like protein 4HB_MCP_1 PF12729.7 CCD25456.1 - 0.023 14.3 1.7 0.023 14.3 1.7 2.6 2 1 1 3 3 3 0 Four helix bundle sensory module for signal transduction HATPase_c_4 PF13749.6 CCD25456.1 - 0.055 13.6 0.4 0.25 11.5 0.1 2.3 2 1 0 2 2 2 0 Putative ATP-dependent DNA helicase recG C-terminal LAM_C PF12544.8 CCD25456.1 - 0.073 13.2 0.4 0.073 13.2 0.4 1.9 2 0 0 2 2 2 0 Lysine-2,3-aminomutase DUF4407 PF14362.6 CCD25456.1 - 0.32 10.3 2.8 0.46 9.8 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 CCD25456.1 - 0.52 10.6 9.7 3 8.2 0.5 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CHIP_TPR_N PF18391.1 CCD25456.1 - 4.7 8.0 9.8 3 8.7 2.0 3.0 1 1 1 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Syntaxin PF00804.25 CCD25457.1 - 7.4e-20 71.5 18.9 9.4e-20 71.1 16.0 2.3 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 CCD25457.1 - 6.7e-14 51.6 2.5 6.7e-14 51.6 2.5 2.4 2 0 0 2 2 2 1 SNARE domain Synaptobrevin PF00957.21 CCD25457.1 - 0.00023 20.9 10.3 0.00034 20.3 1.9 2.8 2 0 0 2 2 2 1 Synaptobrevin SKA1 PF07160.12 CCD25457.1 - 0.0014 18.5 3.3 0.0014 18.5 3.3 2.7 2 1 0 2 2 2 1 Spindle and kinetochore-associated protein 1 T2SSF PF00482.23 CCD25457.1 - 0.071 13.1 1.7 0.18 11.7 1.5 1.8 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F CwsA PF10814.8 CCD25457.1 - 0.073 13.2 3.0 0.07 13.3 1.9 1.6 1 1 0 1 1 1 0 Cell wall synthesis protein CwsA COG5 PF10392.9 CCD25457.1 - 0.17 12.1 10.6 0.89 9.7 0.7 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 ACCA PF03255.14 CCD25457.1 - 1.5 8.7 8.9 0.94 9.4 1.3 2.6 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2951 PF11166.8 CCD25457.1 - 2.1 8.6 14.4 1.1 9.5 0.3 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF2951) SlyX PF04102.12 CCD25457.1 - 4 8.1 12.8 0.36 11.5 5.0 2.9 2 1 1 3 3 3 0 SlyX PCRF PF03462.18 CCD25457.1 - 4.4 7.1 17.2 2.9 7.7 0.4 2.7 1 1 2 3 3 3 0 PCRF domain DUF745 PF05335.13 CCD25457.1 - 9 6.0 19.4 0.65 9.7 11.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Fas_alpha_ACP PF18325.1 CCD25458.1 - 1.8e-73 246.2 0.1 7.8e-73 244.2 0.0 2.1 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 CCD25458.1 - 6.8e-69 231.6 0.5 1.7e-68 230.2 0.2 1.9 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 CCD25458.1 - 2e-18 66.9 0.2 4.6e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 CCD25458.1 - 2.6e-16 59.8 0.0 6.4e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 CCD25458.1 - 1e-12 48.1 0.0 2.9e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain zf-C2H2 PF00096.26 CCD25459.1 - 1.3e-08 34.8 9.2 0.00032 21.0 3.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCD25459.1 - 1.9e-08 34.3 3.9 1.9e-08 34.3 3.9 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCD25459.1 - 0.00031 21.3 7.7 0.046 14.6 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CCD25459.1 - 0.088 13.2 0.4 0.088 13.2 0.4 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CCD25459.1 - 0.15 12.1 3.8 0.45 10.6 3.8 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger mRNA_triPase PF02940.15 CCD25460.1 - 1e-66 224.8 0.1 1e-66 224.8 0.1 2.3 3 0 0 3 3 3 1 mRNA capping enzyme, beta chain Glycos_transf_2 PF00535.26 CCD25461.1 - 8.6e-23 81.0 0.0 1.4e-22 80.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CCD25461.1 - 5.7e-06 26.4 0.0 9.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CCD25461.1 - 0.0054 17.2 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 CCD25461.1 - 0.0082 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cation_efflux PF01545.21 CCD25462.1 - 3.4e-43 147.7 11.3 4.8e-43 147.2 11.3 1.2 1 0 0 1 1 1 1 Cation efflux family UPF0061 PF02696.14 CCD25464.1 - 1.8e-166 554.5 0.0 2.2e-166 554.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family TRP PF06011.12 CCD25465.1 - 2e-159 530.9 35.1 2.6e-159 530.5 35.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CCD25465.1 - 3.1e-40 137.7 0.9 5.4e-40 137.0 0.9 1.4 1 0 0 1 1 1 1 ML-like domain Dysbindin PF04440.16 CCD25465.1 - 0.22 11.7 4.6 0.44 10.7 4.6 1.4 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) Ribosomal_L1 PF00687.21 CCD25466.1 - 9.5e-41 139.8 0.6 1.1e-40 139.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cyclin PF08613.11 CCD25467.1 - 1.6e-15 57.8 3.2 3e-15 57.0 2.8 1.8 1 1 0 1 1 1 1 Cyclin Arf PF00025.21 CCD25468.1 - 5.2e-64 214.9 0.0 5.9e-64 214.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CCD25468.1 - 7.4e-09 35.2 0.7 1.3e-05 24.5 0.1 2.7 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CCD25468.1 - 6.3e-08 32.4 0.0 7.1e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CCD25468.1 - 1.7e-07 30.9 0.0 2.1e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CCD25468.1 - 1.7e-06 28.3 0.0 4.6e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CCD25468.1 - 1e-05 25.6 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CCD25468.1 - 8.4e-05 22.0 0.0 9.5e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CCD25468.1 - 0.0029 17.2 0.1 0.05 13.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SHNi-TPR PF10516.9 CCD25468.1 - 0.16 11.4 0.0 23 4.6 0.0 2.5 2 0 0 2 2 2 0 SHNi-TPR PduV-EutP PF10662.9 CCD25468.1 - 0.21 11.3 0.0 0.46 10.2 0.0 1.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RIBIOP_C PF04950.12 CCD25469.1 - 1.9e-87 293.4 0.8 1.9e-87 293.4 0.8 3.1 3 1 0 3 3 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CCD25469.1 - 2.5e-29 101.2 0.1 1.2e-28 99.0 0.0 2.4 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA PF00004.29 CCD25469.1 - 8.9e-06 26.2 0.1 3.4e-05 24.3 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 CCD25469.1 - 1.6e-05 24.6 4.4 0.0012 18.4 0.0 3.6 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 CCD25469.1 - 4.3e-05 23.7 0.0 0.00021 21.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCD25469.1 - 5.6e-05 23.6 0.0 0.00017 22.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCD25469.1 - 0.0032 17.8 0.0 0.012 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 CCD25469.1 - 0.0057 15.9 0.4 0.021 14.0 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.22 CCD25469.1 - 0.0069 16.8 0.0 0.019 15.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.6 CCD25469.1 - 0.0077 16.0 0.2 0.0077 16.0 0.2 4.4 3 2 0 3 3 2 1 AAA domain AAA_19 PF13245.6 CCD25469.1 - 0.011 16.1 0.1 0.028 14.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CCD25469.1 - 0.016 14.8 0.1 0.034 13.7 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 CCD25469.1 - 0.016 15.3 0.2 0.063 13.4 0.2 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 CCD25469.1 - 0.016 14.7 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region MobB PF03205.14 CCD25469.1 - 0.017 15.0 0.2 0.059 13.3 0.0 2.1 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 CCD25469.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CCD25469.1 - 0.019 14.9 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 CCD25469.1 - 0.02 15.2 0.0 0.065 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CCD25469.1 - 0.021 14.9 0.0 0.062 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CCD25469.1 - 0.025 15.1 0.0 0.025 15.1 0.0 2.7 3 0 0 3 3 2 0 ABC transporter AAA_18 PF13238.6 CCD25469.1 - 0.041 14.4 0.0 0.041 14.4 0.0 4.1 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.15 CCD25469.1 - 0.061 13.2 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 CCD25469.1 - 0.16 11.9 0.7 1.8 8.4 0.1 2.8 2 1 1 3 3 3 0 RsgA GTPase ATP_bind_1 PF03029.17 CCD25469.1 - 0.42 10.4 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein Bac_rhodopsin PF01036.18 CCD25470.1 - 6e-56 189.5 16.7 7e-56 189.3 16.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.6 CCD25470.1 - 8.9 5.9 14.7 1.4 8.6 1.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) WAC_Acf1_DNA_bd PF10537.9 CCD25471.1 - 5.4e-30 103.9 1.9 5.4e-30 103.9 1.9 2.2 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 CCD25471.1 - 1.4e-13 51.1 2.1 2.2e-13 50.5 0.1 2.5 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 CCD25471.1 - 1.8e-10 41.0 0.2 2.3e-08 34.2 0.0 2.9 3 0 0 3 3 3 1 DDT domain Ubiq_cyt_C_chap PF03981.12 CCD25472.1 - 2.4e-43 147.6 1.0 3.8e-43 147.0 1.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone HK PF02110.15 CCD25473.1 - 6.3e-87 291.0 0.3 8.8e-87 290.6 0.3 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 CCD25473.1 - 1e-58 197.6 0.0 1.6e-58 197.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase MRF_C1 PF13887.6 CCD25473.1 - 0.045 12.9 0.0 0.097 11.8 0.0 1.5 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 IMPDH PF00478.25 CCD25473.1 - 0.074 12.0 0.1 0.15 11.0 0.1 1.5 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Knl1_RWD_C PF18210.1 CCD25473.1 - 0.11 13.0 0.1 0.59 10.6 0.0 2.1 2 0 0 2 2 2 0 Knl1 RWD C-terminal domain LRR_9 PF14580.6 CCD25474.1 - 1.2e-17 63.9 0.8 1.2e-17 63.9 0.8 1.7 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 CCD25474.1 - 0.0003 21.1 2.1 0.0003 21.1 2.1 3.1 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) FPV060 PF17614.2 CCD25474.1 - 0.051 12.9 0.6 9.3 5.6 0.0 2.5 3 0 0 3 3 3 0 Viral CC-type chemokine LRR_8 PF13855.6 CCD25474.1 - 0.096 12.5 15.8 0.062 13.1 6.3 3.3 1 1 2 3 3 3 0 Leucine rich repeat CALM_bind PF16025.5 CCD25474.1 - 0.65 10.5 3.8 16 6.0 0.2 2.4 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding Epimerase PF01370.21 CCD25475.1 - 1.8e-17 63.6 0.0 2.4e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCD25475.1 - 9.3e-14 51.1 0.0 1.2e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CCD25475.1 - 4.7e-09 36.1 0.0 6.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CCD25475.1 - 8.4e-09 35.6 0.0 1.2e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CCD25475.1 - 2e-08 33.7 0.1 0.00069 18.9 0.2 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 CCD25475.1 - 0.00019 20.7 0.1 0.00035 19.8 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 CCD25475.1 - 0.00023 20.7 0.0 0.0027 17.2 0.0 2.6 3 1 0 3 3 3 1 short chain dehydrogenase KR PF08659.10 CCD25475.1 - 0.00041 20.3 0.0 0.00069 19.6 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 CCD25475.1 - 0.00047 19.8 0.1 0.32 10.5 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family adh_short_C2 PF13561.6 CCD25475.1 - 0.068 12.7 0.0 0.15 11.6 0.0 1.6 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PseudoU_synth_1 PF01416.20 CCD25476.1 - 1.6e-12 47.8 0.0 7.2e-11 42.5 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 CCD25476.1 - 0.02 14.7 0.0 0.073 12.9 0.0 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) Med15_fungi PF05397.12 CCD25476.1 - 0.16 12.3 0.3 0.65 10.3 0.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit 15 UPF0113_N PF17833.1 CCD25477.1 - 5.9e-30 103.7 0.1 8.4e-30 103.2 0.1 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CCD25477.1 - 2.2e-24 85.5 0.0 5.3e-24 84.3 0.0 1.6 2 0 0 2 2 2 1 UPF0113 PUA domain SRP72 PF08492.12 CCD25478.1 - 5.4e-08 33.1 5.2 5.4e-08 33.1 5.2 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.6 CCD25478.1 - 2.3e-06 27.8 3.8 0.00039 20.7 0.2 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CCD25478.1 - 7.9e-05 22.7 8.3 7.9e-05 22.7 8.3 4.6 4 1 0 4 4 4 1 Putative TPR-like repeat ANAPC3 PF12895.7 CCD25478.1 - 0.0024 18.1 8.6 1.8 8.9 0.1 5.0 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CCD25478.1 - 0.0066 16.6 11.8 0.2 11.9 0.3 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCD25478.1 - 0.091 12.8 1.4 11 6.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 CCD25478.1 - 0.12 12.1 3.1 0.73 9.5 0.1 3.0 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_2 PF07719.17 CCD25478.1 - 0.15 12.3 10.2 1.1 9.6 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 CCD25478.1 - 0.45 10.4 0.1 0.45 10.4 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CCD25478.1 - 0.51 11.1 3.4 50 4.8 0.0 5.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Pkinase PF00069.25 CCD25479.1 - 1.2e-72 244.5 0.0 1.6e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25479.1 - 3.2e-47 161.0 0.0 4.3e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD25479.1 - 3.5e-06 26.5 0.1 1.4e-05 24.5 0.0 2.0 3 1 0 3 3 3 1 Kinase-like Kdo PF06293.14 CCD25479.1 - 0.0044 16.4 0.1 0.012 15.0 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCD25479.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family APH_6_hur PF04655.14 CCD25479.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase FTA2 PF13095.6 CCD25479.1 - 0.26 10.9 4.0 0.33 10.6 0.0 2.6 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CCD25479.1 - 0.27 9.9 0.0 0.27 9.9 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase SET PF00856.28 CCD25480.1 - 1e-08 35.7 0.2 1.9e-08 34.9 0.2 1.5 1 0 0 1 1 1 1 SET domain Wyosine_form PF08608.12 CCD25481.1 - 2.9e-23 82.0 0.0 7e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 CCD25481.1 - 4.6e-22 79.2 0.0 9.8e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 CCD25481.1 - 7.3e-15 55.4 0.0 1.7e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin GDPD PF03009.17 CCD25482.1 - 7.7e-27 94.6 0.1 1.2e-26 94.1 0.1 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Pkinase PF00069.25 CCD25483.1 - 1.2e-24 87.1 0.0 1.2e-24 87.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25483.1 - 3.2e-14 52.8 0.0 6.5e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCD25483.1 - 4.2e-08 32.4 0.5 4.2e-08 32.4 0.5 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CCD25483.1 - 0.027 14.4 0.0 0.027 14.4 0.0 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF1682 PF07946.14 CCD25483.1 - 0.091 11.9 12.1 0.16 11.2 12.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF3915 PF13054.6 CCD25483.1 - 3.2 7.8 9.3 1.7 8.7 6.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) PNISR PF15996.5 CCD25483.1 - 4.9 7.4 21.0 0.79 10.0 17.0 1.6 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Pkinase PF00069.25 CCD25484.1 - 1.1e-71 241.4 0.0 1.6e-71 240.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25484.1 - 2.1e-39 135.4 0.0 2.9e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD25484.1 - 7.8e-07 28.7 0.4 3.8e-06 26.4 0.4 2.2 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CCD25484.1 - 0.023 13.7 2.6 0.055 12.4 2.6 1.5 1 1 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CCD25484.1 - 0.027 14.0 1.5 0.082 12.4 0.0 2.2 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 CCD25484.1 - 0.057 12.5 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 CCD25484.1 - 0.39 10.3 0.0 0.39 10.3 0.0 1.9 2 1 1 3 3 3 0 RIO1 family AFT PF08731.11 CCD25485.1 - 1.9e-35 121.6 2.1 1.9e-35 121.6 2.1 3.6 3 1 0 3 3 3 1 Transcription factor AFT NRIP1_repr_1 PF15687.5 CCD25487.1 - 0.062 13.0 0.0 0.07 12.8 0.0 1.1 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 1 TLD PF07534.16 CCD25488.1 - 1.6e-29 102.9 0.3 2e-14 54.0 0.1 2.3 1 1 0 2 2 2 2 TLD Adaptin_N PF01602.20 CCD25489.1 - 9.7e-111 370.9 16.2 1.3e-110 370.5 16.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CCD25489.1 - 1.1e-11 45.1 4.4 2.3e-11 44.0 0.3 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCD25489.1 - 0.00055 20.3 0.0 0.039 14.3 0.0 3.4 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.22 CCD25489.1 - 0.001 19.2 1.4 5.3 7.6 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat Cnd3 PF12719.7 CCD25489.1 - 0.0022 17.3 1.1 0.056 12.6 0.1 3.0 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 CCD25489.1 - 0.0031 17.7 0.4 0.55 10.4 0.1 3.4 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF1160 PF06648.11 CCD25489.1 - 0.036 14.1 1.7 1.2 9.2 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1160) Med31 PF05669.12 CCD25489.1 - 0.15 12.1 1.4 11 6.1 0.1 3.2 3 0 0 3 3 3 0 SOH1 Peptidase_S49_N PF08496.10 CCD25489.1 - 1.1 9.3 7.7 2.5 8.1 7.7 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rad9 PF04139.13 CCD25490.1 - 1.3e-11 44.5 1.6 8.3e-05 22.2 0.1 2.3 2 0 0 2 2 2 2 Rad9 RRM_1 PF00076.22 CCD25491.1 - 2.1e-37 126.7 0.2 3.8e-17 61.9 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD25491.1 - 0.00024 21.2 0.0 0.00092 19.3 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CCD25491.1 - 0.00038 20.4 0.1 0.027 14.5 0.0 2.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CCD25491.1 - 0.0031 17.3 0.0 0.45 10.4 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 CCD25491.1 - 0.0033 17.5 0.0 0.016 15.2 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif LydB PF16084.5 CCD25492.1 - 0.02 14.7 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 LydA-holin antagonist HlyIII PF03006.20 CCD25493.1 - 5.8e-53 179.9 22.3 6.9e-53 179.6 22.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF2076 PF09849.9 CCD25494.1 - 4.3e-07 30.2 8.8 5.9e-07 29.8 8.8 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 CCD25494.1 - 0.0002 21.4 4.1 0.00031 20.8 4.1 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 CCD25494.1 - 0.048 13.7 1.1 0.084 12.9 1.1 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Antimicrobial24 PF16049.5 CCD25494.1 - 0.071 13.1 0.8 0.14 12.1 0.8 1.4 1 0 0 1 1 1 0 Frog antimicrobial peptide NAD_binding_7 PF13241.6 CCD25495.1 - 1.7e-22 79.9 0.0 2.4e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 CCD25495.1 - 9.1e-12 44.4 0.0 2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 CCD25495.1 - 2e-09 36.7 0.1 3.8e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_2 PF07992.14 CCD25495.1 - 0.036 13.3 0.0 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Spermine_synth PF01564.17 CCD25495.1 - 0.12 11.7 0.0 0.23 10.9 0.0 1.5 2 0 0 2 2 2 0 Spermine/spermidine synthase domain CBS PF00571.28 CCD25496.1 - 9.6e-20 70.8 2.8 0.00011 22.5 0.0 5.3 5 0 0 5 5 5 5 CBS domain CPSase_L_D2 PF02786.17 CCD25497.1 - 9.8e-84 280.1 0.1 1.6e-83 279.4 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 CCD25497.1 - 1.4e-67 227.3 0.0 2.4e-67 226.6 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_C PF02785.19 CCD25497.1 - 4.8e-31 107.1 0.0 2e-30 105.1 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 CCD25497.1 - 6.4e-27 94.8 0.1 1.5e-26 93.5 0.1 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_carb_N PF00289.22 CCD25497.1 - 1.3e-26 93.3 0.0 2.9e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 CCD25497.1 - 1.3e-19 69.8 4.3 1.3e-19 69.8 4.3 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CCD25497.1 - 1.1e-08 34.8 2.9 0.00075 19.3 0.5 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 CCD25497.1 - 6.1e-08 32.4 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CCD25497.1 - 2.2e-07 30.6 0.0 4.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 CCD25497.1 - 7.7e-07 29.3 0.0 2.1e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 CCD25497.1 - 3.6e-05 23.1 0.3 0.014 14.6 0.1 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CCD25497.1 - 0.00012 22.7 1.6 0.89 10.3 0.1 3.3 3 0 0 3 3 2 2 HlyD family secretion protein ATPgrasp_ST PF14397.6 CCD25497.1 - 0.0017 17.6 0.0 0.0041 16.4 0.0 1.6 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp NQRA PF05896.11 CCD25497.1 - 0.0044 16.5 0.1 0.0083 15.6 0.1 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATP-grasp_4 PF13535.6 CCD25497.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain RnfC_N PF13375.6 CCD25497.1 - 0.033 14.1 1.7 0.13 12.2 1.0 2.4 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 CCD25497.1 - 0.078 12.9 0.8 0.22 11.4 0.8 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein APG12 PF04110.13 CCD25498.1 - 6.7e-30 103.3 0.0 1e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Kinetochor_Ybp2 PF08568.10 CCD25499.1 - 7e-129 431.2 11.6 8.4e-129 430.9 11.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin HUN PF08729.10 CCD25500.1 - 1e-06 28.6 0.6 1e-06 28.6 0.6 2.4 1 1 1 2 2 2 1 HPC2 and ubinuclein domain RRP7 PF12923.7 CCD25500.1 - 0.088 12.9 2.0 0.31 11.2 0.7 2.6 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain CRA PF06589.11 CCD25500.1 - 0.39 10.8 4.1 0.5 10.5 0.0 3.2 2 1 1 3 3 3 0 Circumsporozoite-related antigen (CRA) Acatn PF13000.7 CCD25501.1 - 8.2e-282 935.6 11.4 9.2e-282 935.4 11.4 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Transket_pyr PF02779.24 CCD25502.1 - 2.6e-48 164.0 0.0 7.4e-48 162.6 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CCD25502.1 - 1.1e-37 128.6 0.1 2.2e-37 127.7 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain AMP-binding PF00501.28 CCD25503.1 - 6.3e-72 242.5 0.0 8.4e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCD25503.1 - 1.3e-15 58.1 0.6 3e-15 57.0 0.2 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RTX_C PF08339.10 CCD25503.1 - 0.053 13.6 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 RTX C-terminal domain Tyr-DNA_phospho PF06087.12 CCD25504.1 - 1.9e-96 323.6 9.6 2.7e-96 323.1 9.6 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase BBIP10 PF14777.6 CCD25504.1 - 0.0078 15.8 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 Methyltransf_11 PF08241.12 CCD25505.1 - 6.5e-05 23.5 0.0 0.00037 21.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCD25505.1 - 0.18 12.5 0.0 0.7 10.6 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain SH3BGR PF04908.15 CCD25505.1 - 1.1 9.4 8.3 2.5 8.3 0.2 3.0 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein TFIIA PF03153.13 CCD25505.1 - 6.4 6.7 49.9 2.1 8.2 6.6 3.3 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit AAA_2 PF07724.14 CCD25506.1 - 1.2e-35 123.2 0.2 2.5e-35 122.1 0.2 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CCD25506.1 - 2.2e-14 54.0 0.2 4.3e-14 53.1 0.2 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CCD25506.1 - 1.2e-08 34.9 0.3 8.1e-08 32.2 0.0 2.5 2 1 1 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CCD25506.1 - 1.4e-06 28.3 0.0 3.7e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCD25506.1 - 3.9e-05 23.9 0.5 0.0013 19.0 0.3 2.8 2 2 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CCD25506.1 - 7e-05 22.3 0.0 0.0054 16.1 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CCD25506.1 - 0.00017 22.0 0.1 0.0011 19.4 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 CCD25506.1 - 0.0005 19.8 0.0 0.084 12.6 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_24 PF13479.6 CCD25506.1 - 0.00075 19.3 0.2 0.0029 17.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 CCD25506.1 - 0.0017 18.5 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 CCD25506.1 - 0.0027 17.5 0.2 0.012 15.4 0.1 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CCD25506.1 - 0.008 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein MCM PF00493.23 CCD25506.1 - 0.015 14.4 0.2 0.029 13.5 0.2 1.4 1 0 0 1 1 1 0 MCM P-loop domain NACHT PF05729.12 CCD25506.1 - 0.016 15.1 0.1 0.25 11.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain T2SSE PF00437.20 CCD25506.1 - 0.017 14.2 0.2 0.035 13.1 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein DEAD PF00270.29 CCD25506.1 - 0.02 14.7 0.1 0.76 9.5 0.0 3.0 3 0 0 3 3 3 0 DEAD/DEAH box helicase ABC_tran PF00005.27 CCD25506.1 - 0.02 15.4 0.0 0.063 13.8 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 CCD25506.1 - 0.021 15.0 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CCD25506.1 - 0.021 14.3 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 CCD25506.1 - 0.024 14.7 0.0 0.073 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CCD25506.1 - 0.04 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 CCD25506.1 - 0.063 13.8 0.3 0.19 12.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 CCD25506.1 - 0.093 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.6 CCD25506.1 - 8.2 6.9 11.3 4.9 7.6 1.6 3.0 2 1 0 2 2 2 0 AAA domain FANCL_C PF11793.8 CCD25507.1 - 0.00022 21.3 1.3 0.00022 21.3 1.3 1.7 2 0 0 2 2 2 1 FANCL C-terminal domain Zf_RING PF16744.5 CCD25507.1 - 0.063 13.4 3.5 0.2 11.8 0.3 2.3 2 0 0 2 2 2 0 KIAA1045 RING finger Glyco_hydro_31 PF01055.26 CCD25508.1 - 2.3e-122 409.4 0.0 3.4e-122 408.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CCD25508.1 - 1e-23 83.4 1.8 2.4e-23 82.2 0.1 2.6 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 CCD25508.1 - 2.1e-07 31.1 0.1 1.7e-06 28.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) Neur_chan_memb PF02932.16 CCD25509.1 - 1 9.3 3.4 1.2 9.2 3.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CCD25509.1 - 8 5.1 5.5 9.4 4.9 5.5 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_U4 PF03419.13 CCD25510.1 - 0.59 9.4 3.6 0.82 8.9 3.6 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Sugar_tr PF00083.24 CCD25511.1 - 1.4e-160 535.1 33.2 1.6e-160 534.9 33.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD25511.1 - 5.4e-33 114.4 24.1 5.4e-33 114.4 24.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 CCD25511.1 - 0.0037 15.7 2.6 0.0037 15.7 2.6 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector DUF1772 PF08592.11 CCD25511.1 - 1.8 8.9 11.2 20 5.5 5.4 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Sugar_tr PF00083.24 CCD25512.1 - 4.3e-161 536.8 32.6 5e-161 536.6 32.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD25512.1 - 1.3e-33 116.4 21.5 1.3e-33 116.4 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCD25512.1 - 0.00045 18.8 1.7 0.00077 18.0 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1772 PF08592.11 CCD25512.1 - 0.31 11.4 7.8 2.1 8.6 2.3 3.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) BCNT PF07572.12 CCD25513.1 - 1.3e-24 86.1 1.4 1.3e-24 86.1 1.4 2.6 3 0 0 3 3 3 1 Bucentaur or craniofacial development RRN3 PF05327.11 CCD25513.1 - 2.4 6.6 15.7 4.3 5.8 15.7 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 KH_1 PF00013.29 CCD25514.1 - 8.9e-24 83.1 3.7 3e-10 39.8 0.4 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CCD25514.1 - 4.7e-07 29.5 1.8 0.00068 19.4 0.1 2.7 2 1 0 2 2 2 2 KH domain KH_4 PF13083.6 CCD25514.1 - 2.5e-05 24.1 0.5 0.039 13.8 0.0 2.7 2 1 0 2 2 2 2 KH domain KH_5 PF13184.6 CCD25514.1 - 0.012 15.7 0.4 4.2 7.5 0.0 2.5 2 0 0 2 2 2 0 NusA-like KH domain F-box PF00646.33 CCD25515.1 - 0.0019 18.0 0.5 0.0046 16.8 0.5 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CCD25515.1 - 0.0064 16.4 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like Ku_PK_bind PF08785.11 CCD25515.1 - 0.025 14.7 0.6 1.9 8.7 0.0 2.7 2 0 0 2 2 2 0 Ku C terminal domain like AA_permease PF00324.21 CCD25517.1 - 1.8e-44 152.1 39.3 2.6e-44 151.6 39.3 1.2 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 CCD25517.1 - 2.5e-13 49.9 2.4 1e-07 31.4 0.1 3.3 3 0 0 3 3 3 3 Solute carrier family 12 Pox_MCEL PF03291.16 CCD25518.1 - 8.2e-103 344.0 0.1 1.1e-102 343.6 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CCD25518.1 - 1.3e-10 41.8 0.0 2.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCD25518.1 - 1.2e-09 38.8 0.1 1.7e-08 35.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCD25518.1 - 7.2e-08 33.0 0.0 1.8e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCD25518.1 - 7.1e-06 26.0 0.1 2.3e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCD25518.1 - 9.4e-06 25.5 0.0 2.4e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CCD25518.1 - 0.0063 15.7 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_15 PF09445.10 CCD25518.1 - 0.025 14.2 2.0 0.51 9.9 0.0 2.2 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 CCD25518.1 - 0.05 13.1 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase Glyco_hydro_108 PF05838.12 CCD25518.1 - 0.12 12.9 0.3 0.39 11.2 0.3 2.0 1 1 0 1 1 1 0 Glycosyl hydrolase 108 Methyltransf_32 PF13679.6 CCD25518.1 - 0.82 9.6 6.3 3.3 7.7 0.1 2.3 1 1 0 2 2 2 0 Methyltransferase domain CDC45 PF02724.14 CCD25518.1 - 9.4 4.4 7.7 16 3.7 7.7 1.3 1 0 0 1 1 1 0 CDC45-like protein DEAD PF00270.29 CCD25519.1 - 3e-48 163.9 0.5 8.2e-48 162.5 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD25519.1 - 1.5e-20 73.5 0.2 1.5e-20 73.5 0.2 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD25519.1 - 1.7e-07 31.4 0.0 1.7e-07 31.4 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Fis1_TPR_N PF14852.6 CCD25519.1 - 0.0074 15.9 0.2 0.014 15.1 0.2 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat Patatin PF01734.22 CCD25520.1 - 4.7 7.3 6.6 0.3 11.3 0.2 2.2 2 1 0 2 2 2 0 Patatin-like phospholipase PAS PF00989.25 CCD25521.1 - 8.8e-14 51.5 0.4 6.4e-13 48.7 0.0 2.2 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 CCD25521.1 - 9.4e-07 28.9 10.8 1.7e-06 28.0 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1189 PF06691.11 CCD25521.1 - 1.5 8.3 5.1 1.5 8.3 3.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) tRNA_bind PF01588.20 CCD25522.1 - 2.6e-28 97.9 0.0 5e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 CCD25522.1 - 0.023 14.7 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Viral_protease PF08715.10 CCD25522.1 - 0.05 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Papain like viral protease GAGA_bind PF06217.12 CCD25522.1 - 0.079 13.2 1.3 0.11 12.8 1.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Med3 PF11593.8 CCD25522.1 - 0.14 11.3 17.0 0.32 10.1 13.6 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Zn_clus PF00172.18 CCD25523.1 - 2.2e-10 40.5 7.2 6.2e-10 39.0 7.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 CCD25524.1 - 3.2e-103 346.0 15.0 3.8e-103 345.8 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD25524.1 - 4.5e-34 117.9 12.8 4.5e-34 117.9 12.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 CCD25524.1 - 2.8e-06 26.9 4.6 2.8e-06 26.9 4.6 2.4 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB ATG7_N PF16420.5 CCD25524.1 - 0.011 15.4 0.3 0.017 14.8 0.3 1.2 1 0 0 1 1 1 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus DUF3180 PF11377.8 CCD25524.1 - 0.32 11.2 0.0 0.32 11.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) HD_3 PF13023.6 CCD25525.1 - 4.7e-42 143.7 0.4 5.9e-42 143.4 0.4 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CCD25525.1 - 4.9e-13 49.2 0.2 6.4e-13 48.9 0.2 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CCD25525.1 - 2.5e-06 27.7 0.2 4.4e-06 26.9 0.2 1.4 1 0 0 1 1 1 1 HD domain Glycos_transf_4 PF00953.21 CCD25526.1 - 1.3e-30 106.5 11.6 1.3e-30 106.5 11.6 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 4 SNF2_N PF00176.23 CCD25527.1 - 1.9e-73 247.2 0.5 1.9e-73 247.2 0.5 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 CCD25527.1 - 1.9e-29 102.0 2.3 1.9e-29 102.0 2.3 3.9 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 CCD25527.1 - 1.4e-27 96.6 0.4 1.4e-27 96.6 0.4 4.2 5 0 0 5 5 5 1 HAND Helicase_C PF00271.31 CCD25527.1 - 1.4e-20 73.7 0.6 8.6e-20 71.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CCD25527.1 - 1.4e-09 37.5 0.2 3.9e-09 36.1 0.2 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 CCD25527.1 - 6.9e-09 35.9 0.0 6.9e-09 35.9 0.0 3.9 6 0 0 6 6 6 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CCD25527.1 - 0.00026 20.3 0.7 0.00026 20.3 0.7 2.1 2 1 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 CCD25527.1 - 0.00037 20.3 0.0 0.001 18.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase NYD-SP28_assoc PF14775.6 CCD25527.1 - 0.055 13.6 5.0 0.31 11.2 5.0 2.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain WD40 PF00400.32 CCD25528.1 - 0.0012 19.6 8.2 4.3 8.4 0.0 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD25528.1 - 0.0027 18.0 0.2 0.77 10.1 0.1 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain MMR_HSR1 PF01926.23 CCD25529.1 - 2.7e-16 59.6 0.2 1.7e-14 53.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCD25529.1 - 2.8e-08 33.4 0.2 1.5e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CCD25529.1 - 2.9e-08 33.8 0.2 0.0067 16.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 CCD25529.1 - 0.004 16.5 0.0 0.0086 15.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 CCD25529.1 - 0.0042 17.2 0.5 0.047 13.7 0.1 2.8 2 1 0 2 2 2 1 Dynamin family SRP1_TIP1 PF00660.17 CCD25530.1 - 8.7e-20 70.7 0.2 9.6e-20 70.5 0.2 1.0 1 0 0 1 1 1 1 Seripauperin and TIP1 family Bystin PF05291.11 CCD25531.1 - 1.1e-122 408.9 0.0 1.8e-122 408.2 0.0 1.3 1 0 0 1 1 1 1 Bystin TcdB_toxin_midN PF12256.8 CCD25531.1 - 0.086 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region His_biosynth PF00977.21 CCD25532.1 - 2.4e-44 151.5 0.0 1.1e-43 149.4 0.0 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 CCD25532.1 - 6.5e-22 78.2 0.0 1.3e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 CCD25532.1 - 1.6e-06 27.9 0.0 3.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 CCD25532.1 - 1.5e-05 24.9 0.0 0.0092 15.8 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 CCD25532.1 - 0.004 16.9 0.4 0.033 13.9 0.4 2.1 1 1 0 1 1 1 1 Peptidase C26 DAHP_synth_1 PF00793.20 CCD25533.1 - 1.2e-107 359.0 0.0 1.4e-107 358.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Arrestin_C PF02752.22 CCD25534.1 - 5.9e-06 26.8 0.2 1.7e-05 25.3 0.2 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCD25534.1 - 0.0006 19.9 0.6 0.0013 18.8 0.6 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain HTH_30 PF13556.6 CCD25534.1 - 0.046 13.5 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Homeobox_KN PF05920.11 CCD25535.1 - 5.9e-18 64.5 0.7 5.9e-18 64.5 0.7 2.7 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CCD25535.1 - 9.9e-06 25.3 0.4 4.1e-05 23.3 0.3 2.1 2 0 0 2 2 2 1 Homeodomain Metallophos PF00149.28 CCD25537.1 - 9.3e-39 134.0 0.5 2.6e-38 132.6 0.1 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CCD25537.1 - 4.9e-14 52.5 0.6 5.3e-13 49.2 0.6 2.4 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Sec1 PF00995.23 CCD25540.1 - 9.1e-116 388.4 31.5 1.7e-115 387.5 31.5 1.4 1 1 0 1 1 1 1 Sec1 family DUF1353 PF07087.11 CCD25540.1 - 0.036 13.8 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) CHDCT2 PF08074.11 CCD25540.1 - 0.043 14.0 1.0 0.15 12.3 1.0 1.9 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain DHR10 PF18595.1 CCD25540.1 - 0.26 11.4 2.1 1.2 9.2 0.7 2.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Occludin_ELL PF07303.13 CCD25540.1 - 0.96 10.2 7.7 4.3 8.1 0.2 4.1 3 1 0 3 3 3 0 Occludin homology domain TCO89 PF10452.9 CCD25541.1 - 2.2e-72 244.9 81.4 2.2e-72 244.9 81.4 3.2 2 1 0 2 2 2 1 TORC1 subunit TCO89 WD40 PF00400.32 CCD25542.1 - 8.4e-23 80.2 17.7 9.7e-08 32.6 0.4 9.7 10 0 0 10 10 10 4 WD domain, G-beta repeat Kelch_6 PF13964.6 CCD25542.1 - 0.015 15.5 0.9 21 5.6 0.0 5.0 4 0 0 4 4 4 0 Kelch motif CPSF_A PF03178.15 CCD25542.1 - 0.025 13.9 0.6 0.68 9.2 0.0 3.4 4 0 0 4 4 4 0 CPSF A subunit region PH_8 PF15409.6 CCD25542.1 - 0.25 11.7 1.0 38 4.7 0.0 4.0 3 1 0 3 3 3 0 Pleckstrin homology domain Ribosomal_L36 PF00444.18 CCD25543.1 - 2.9e-22 78.6 9.4 4e-22 78.1 9.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 DUF3228 PF11539.8 CCD25543.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) DUF4193 PF13834.6 CCD25543.1 - 0.11 13.0 0.2 0.31 11.5 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4193) RRM_1 PF00076.22 CCD25544.1 - 3e-24 84.6 0.9 2.5e-06 27.2 0.0 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCD25544.1 - 2e-13 50.0 0.1 0.12 12.3 0.0 4.5 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM_5 PF13893.6 CCD25544.1 - 5.5e-05 22.8 0.2 0.012 15.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMPK1_CBM PF16561.5 CCD25545.1 - 0.0003 20.9 0.2 0.00072 19.7 0.2 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase MF_alpha_N PF05436.11 CCD25546.1 - 1.2e-29 102.0 0.3 1.4e-29 101.8 0.3 1.0 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus NAD_kinase PF01513.21 CCD25547.1 - 4.2e-55 187.0 0.1 6.2e-55 186.4 0.1 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 CCD25547.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain MBOAT PF03062.19 CCD25548.1 - 3.4e-69 233.8 20.7 3.4e-69 233.8 20.7 2.1 3 0 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family Sad1_UNC PF07738.13 CCD25549.1 - 1.8e-31 108.9 0.1 5.1e-31 107.4 0.1 1.8 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal KRAP_IP3R_bind PF14722.6 CCD25549.1 - 3.9e-05 23.4 0.2 0.00011 22.0 0.2 1.7 1 0 0 1 1 1 1 Ki-ras-induced actin-interacting protein-IP3R-interacting domain FBA_2 PF07735.17 CCD25549.1 - 1.7 8.8 9.4 0.18 11.9 1.9 2.9 2 0 0 2 2 2 0 F-box associated COA2 PF17051.5 CCD25550.1 - 9.9e-16 57.6 0.0 1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 INSIG PF07281.12 CCD25550.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.0 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) RRT14 PF17075.5 CCD25553.1 - 1.5e-51 175.3 32.9 1.8e-51 175.1 32.9 1.0 1 0 0 1 1 1 1 Regular of rDNA transcription protein 14 MMS19_C PF12460.8 CCD25554.1 - 2.9e-100 336.3 32.0 5.8e-98 328.8 20.1 3.3 3 0 0 3 3 3 3 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 CCD25554.1 - 2.8e-75 253.3 10.3 1.9e-73 247.3 2.3 4.4 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 CCD25554.1 - 0.0054 17.2 0.4 0.073 13.6 0.1 2.9 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 CCD25554.1 - 0.0074 16.5 0.0 12 6.5 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat Ipi1_N PF12333.8 CCD25554.1 - 0.31 11.6 9.8 7 7.3 0.2 5.0 5 1 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation Arm-DNA-bind_5 PF17293.2 CCD25554.1 - 1.8 9.1 4.7 6.3 7.3 0.5 2.8 2 0 0 2 2 2 0 Arm DNA-binding domain Forkhead PF00250.18 CCD25555.1 - 9e-33 112.4 0.2 3.2e-32 110.6 0.2 2.0 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 CCD25555.1 - 4e-09 36.7 0.1 2e-08 34.5 0.1 2.3 1 0 0 1 1 1 1 FHA domain Linker_histone PF00538.19 CCD25555.1 - 0.0033 17.8 0.1 0.011 16.1 0.1 1.9 1 0 0 1 1 1 1 linker histone H1 and H5 family FHA_2 PF17913.1 CCD25555.1 - 0.017 15.4 3.2 0.044 14.0 0.0 2.8 2 0 0 2 2 2 0 FHA domain Ribosomal_L13 PF00572.18 CCD25556.1 - 3.4e-11 43.5 0.1 4.2e-09 36.7 0.1 2.5 1 1 0 1 1 1 1 Ribosomal protein L13 Tom7 PF08038.12 CCD25557.1 - 1.9e-18 65.9 0.1 2.4e-18 65.5 0.1 1.2 1 0 0 1 1 1 1 TOM7 family 2-oxoacid_dh PF00198.23 CCD25558.1 - 1.1e-75 254.1 0.7 1.6e-75 253.6 0.7 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CCD25558.1 - 3.3e-16 58.9 0.1 7.8e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CCD25558.1 - 7.4e-14 51.8 0.1 2.1e-13 50.4 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain CPSF100_C PF13299.6 CCD25558.1 - 0.36 11.0 4.4 1.3 9.2 4.4 1.9 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNase_HII PF01351.18 CCD25559.1 - 6.4e-66 222.0 0.0 7.7e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Brix PF04427.18 CCD25561.1 - 1e-30 107.3 0.1 1.4e-30 106.9 0.1 1.2 1 0 0 1 1 1 1 Brix domain DUF4128 PF13554.6 CCD25561.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function DUF1752 PF08550.10 CCD25562.1 - 3.3e-10 39.6 0.1 1.2e-09 37.8 0.1 2.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DnaJ_C PF01556.18 CCD25563.1 - 1.8e-22 80.0 0.0 4.3e-22 78.8 0.0 1.7 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCD25563.1 - 8.3e-22 77.1 3.5 1.9e-21 75.9 3.5 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CCD25563.1 - 3.2e-11 43.4 15.6 8.8e-11 42.0 15.6 1.8 1 0 0 1 1 1 1 DnaJ central domain Adeno_E3B PF03376.14 CCD25565.1 - 9.2 6.6 6.2 47 4.3 0.6 2.6 2 0 0 2 2 2 0 Adenovirus E3B protein EOS1 PF12326.8 CCD25566.1 - 8.6e-47 159.3 0.8 2.2e-46 158.0 0.1 1.9 2 0 0 2 2 2 1 N-glycosylation protein Ribosomal_S13 PF00416.22 CCD25567.1 - 8.3e-17 61.8 0.1 7.6e-15 55.4 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CCD25567.1 - 0.0042 15.9 0.0 0.0042 15.9 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) IMS_HHH PF11798.8 CCD25567.1 - 0.016 15.5 0.0 0.039 14.3 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif DUF1182 PF06681.13 CCD25567.1 - 0.17 11.5 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) DNA_mis_repair PF01119.19 CCD25569.1 - 5.1e-24 84.2 0.3 5.1e-24 84.2 0.3 2.0 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 CCD25569.1 - 8.4e-24 84.0 0.5 1.5e-23 83.2 0.0 1.7 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 CCD25569.1 - 2.5e-10 40.3 2.7 6.5e-10 39.0 0.0 2.8 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CCD25569.1 - 3.5e-06 27.5 0.1 1.3e-05 25.7 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mito_carr PF00153.27 CCD25570.1 - 1e-60 201.7 4.4 1.9e-21 75.7 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 CCD25570.1 - 1.2e-14 54.5 2.7 2e-09 37.8 1.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCD25570.1 - 2.1e-10 39.6 4.7 0.011 15.6 0.1 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 CCD25570.1 - 6.4e-09 34.7 4.9 0.019 14.5 0.2 4.8 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 CCD25570.1 - 6.8e-08 32.2 2.5 8.7e-06 25.5 0.4 3.1 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CCD25570.1 - 0.00037 19.8 2.5 0.072 12.6 0.1 2.9 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 CCD25570.1 - 0.0046 17.3 3.3 0.019 15.3 0.5 2.5 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Snapin_Pallidin PF14712.6 CCD25571.1 - 0.00015 22.1 4.9 0.00019 21.8 4.9 1.1 1 0 0 1 1 1 1 Snapin/Pallidin YscO PF07321.12 CCD25571.1 - 0.0013 18.7 1.0 0.0017 18.3 1.0 1.2 1 0 0 1 1 1 1 Type III secretion protein YscO YabA PF06156.13 CCD25571.1 - 0.36 11.5 3.0 5.8 7.6 0.4 2.0 1 1 1 2 2 2 0 Initiation control protein YabA DUF2205 PF10224.9 CCD25571.1 - 0.74 9.9 7.3 1.2 9.2 3.5 2.4 1 1 1 2 2 2 0 Short coiled-coil protein C2 PF00168.30 CCD25572.1 - 8.6e-52 173.7 2.4 4.6e-22 78.2 0.0 5.4 5 0 0 5 5 5 5 C2 domain DNA_topoisoIV PF00521.20 CCD25573.1 - 4.5e-125 417.9 0.0 4.5e-125 417.9 0.0 2.0 3 0 0 3 3 3 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CCD25573.1 - 1.9e-49 167.2 0.6 1.2e-48 164.6 0.6 2.5 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CCD25573.1 - 1.6e-26 92.8 4.0 3.2e-26 91.9 4.0 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CCD25573.1 - 3.1e-13 50.2 0.0 9.7e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CCD25573.1 - 1e-07 32.1 0.0 3.5e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Ras PF00071.22 CCD25574.1 - 5.9e-50 169.0 0.0 6.7e-50 168.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD25574.1 - 1e-22 80.6 0.0 1.4e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD25574.1 - 2.4e-08 33.6 0.0 3.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CCD25574.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 CCD25574.1 - 0.2 11.4 0.0 16 5.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NST1 PF13945.6 CCD25575.1 - 2.1e-13 50.8 0.5 2.1e-13 50.8 0.5 11.1 6 5 4 10 10 10 3 Salt tolerance down-regulator DFRP_C PF16543.5 CCD25576.1 - 2.7e-21 75.9 7.9 2.7e-21 75.9 7.9 4.4 3 2 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf_CCCH_4 PF18345.1 CCD25576.1 - 0.00011 22.1 15.5 0.00023 21.1 4.7 3.0 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 CCD25576.1 - 0.00024 21.8 4.9 0.00024 21.8 4.9 3.9 2 2 2 4 4 4 2 Torus domain zf-CCCH PF00642.24 CCD25576.1 - 0.0011 18.8 0.2 0.0011 18.8 0.2 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CCD25576.1 - 0.0022 17.8 9.4 0.033 14.0 1.4 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CCD25576.1 - 0.13 12.8 13.9 1.4 9.5 3.7 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CCD25576.1 - 1.4 9.2 11.3 1.6 9.0 0.7 3.3 2 1 1 3 3 3 0 Zinc-finger containing family DUF2183 PF09949.9 CCD25577.1 - 4.6e-31 107.1 0.1 2.2e-30 104.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Mem_trans PF03547.18 CCD25578.1 - 3.7e-27 94.7 3.7 5e-27 94.3 3.7 1.2 1 0 0 1 1 1 1 Membrane transport protein Ribosomal_S7e PF01251.18 CCD25579.1 - 1.2e-22 80.6 0.2 1.3e-22 80.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ING PF12998.7 CCD25580.1 - 1.1e-22 80.5 1.1 1.1e-22 80.5 1.1 2.0 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CCD25580.1 - 3.8e-05 23.5 7.2 6.7e-05 22.7 7.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CCD25580.1 - 0.0044 17.2 0.7 0.013 15.7 0.7 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CCD25580.1 - 0.011 15.2 1.4 0.025 14.1 1.4 1.6 1 0 0 1 1 1 0 PHD-finger Glyco_transf_41 PF13844.6 CCD25580.1 - 0.18 10.2 3.5 0.27 9.6 3.5 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 Hamartin PF04388.12 CCD25580.1 - 0.27 9.8 16.8 0.36 9.4 16.8 1.0 1 0 0 1 1 1 0 Hamartin protein SWI-SNF_Ssr4 PF08549.10 CCD25580.1 - 0.73 8.4 10.9 0.88 8.1 10.9 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF572 PF04502.13 CCD25580.1 - 3.3 7.2 21.8 4.8 6.7 21.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DAD PF02109.16 CCD25581.1 - 9.2e-39 132.1 5.1 1.3e-38 131.7 5.1 1.2 1 0 0 1 1 1 1 DAD family PalH PF08733.10 CCD25581.1 - 0.00012 21.2 2.7 0.00014 21.0 2.7 1.0 1 0 0 1 1 1 1 PalH/RIM21 DUF2207 PF09972.9 CCD25581.1 - 0.012 14.4 0.6 0.014 14.2 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Y_phosphatase2 PF03162.13 CCD25582.1 - 2.5e-57 193.0 0.0 3.7e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CCD25582.1 - 2.6e-05 24.3 0.0 7.9e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CCD25582.1 - 0.032 14.0 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CCD25582.1 - 0.065 13.3 1.8 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 CCD25582.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ApoO PF09769.9 CCD25583.1 - 1.1e-05 25.4 0.0 0.041 13.9 0.0 2.9 3 0 0 3 3 3 2 Apolipoprotein O Aa_trans PF01490.18 CCD25584.1 - 1.2e-90 304.2 30.5 1.4e-90 303.9 30.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YuzL PF14115.6 CCD25584.1 - 2 9.0 5.0 0.34 11.4 0.4 2.0 2 0 0 2 2 2 0 YuzL-like protein DNA_pol_B PF00136.21 CCD25585.1 - 6.7e-124 414.1 3.4 9.9e-124 413.5 3.4 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 CCD25585.1 - 2.5e-65 219.7 1.6 4.4e-65 218.9 1.6 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 CCD25585.1 - 6.5e-43 147.2 0.0 1.6e-42 145.9 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain Neur_chan_memb PF02932.16 CCD25587.1 - 0.81 9.7 5.9 0.91 9.5 5.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Syja_N PF02383.18 CCD25588.1 - 1.9e-75 254.2 4.3 4.1e-75 253.1 4.3 1.6 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 CCD25588.1 - 1.1e-13 51.3 0.0 1.7e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Remorin_N PF03766.13 CCD25588.1 - 0.12 12.4 3.2 0.36 10.9 3.2 1.8 1 0 0 1 1 1 0 Remorin, N-terminal region His_Phos_1 PF00300.22 CCD25589.1 - 1.1e-17 64.4 0.0 3.3e-17 62.8 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.22 CCD25590.1 - 4.9e-19 67.9 0.2 1.8e-18 66.1 0.1 2.0 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2129 PF09902.9 CCD25590.1 - 0.01 15.9 1.3 3.2 7.9 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2129) RRM_5 PF13893.6 CCD25590.1 - 0.01 15.4 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 CCD25590.1 - 0.016 15.2 0.4 0.079 12.9 0.2 2.3 2 1 0 2 2 2 0 RL domain Nup35_RRM_2 PF14605.6 CCD25590.1 - 0.14 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CarD_CdnL_TRCF PF02559.16 CCD25590.1 - 0.74 10.6 7.8 0.1 13.3 1.0 2.5 2 1 0 2 2 2 0 CarD-like/TRCF domain Spore_II_R PF09551.10 CCD25590.1 - 1.3 9.5 10.8 0.15 12.5 4.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) AAA_23 PF13476.6 CCD25590.1 - 6.3 7.2 21.4 2.3 8.7 12.1 2.1 2 0 0 2 2 2 0 AAA domain Cyt-b5 PF00173.28 CCD25591.1 - 5.7e-27 93.7 0.1 7.3e-27 93.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DEAD PF00270.29 CCD25592.1 - 1.4e-48 165.0 0.0 1.3e-47 161.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD25592.1 - 3.8e-32 110.9 0.0 1.8e-31 108.7 0.0 2.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD25592.1 - 0.00018 21.6 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF5335 PF17269.2 CCD25592.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5335) AAA_19 PF13245.6 CCD25592.1 - 0.017 15.5 0.0 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 CCD25592.1 - 0.083 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 CCD25592.1 - 0.12 11.2 0.0 1.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 RNA_pol_L_2 PF13656.6 CCD25593.1 - 9.5e-34 115.0 0.0 1.5e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CCD25593.1 - 5e-15 54.7 0.0 8.6e-15 53.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mem_trans PF03547.18 CCD25593.1 - 0.28 9.6 0.3 0.29 9.5 0.3 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF2417 PF10329.9 CCD25594.1 - 5.8e-69 232.1 12.0 9.4e-69 231.4 12.0 1.3 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_1 PF00561.20 CCD25594.1 - 2.6e-05 24.0 0.2 4.3e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold FHA PF00498.26 CCD25595.1 - 4.9e-15 55.6 0.1 4.9e-15 55.6 0.1 2.6 3 0 0 3 3 2 1 FHA domain zf-RING_11 PF17123.5 CCD25595.1 - 3.5e-10 39.4 10.8 7e-10 38.5 10.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CCD25595.1 - 5.9e-07 29.7 10.7 1e-06 29.0 10.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CCD25595.1 - 0.00044 20.5 8.6 0.0011 19.2 8.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Yop-YscD_cpl PF16697.5 CCD25595.1 - 0.0019 18.5 0.0 0.0055 17.0 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 CCD25595.1 - 0.0028 17.5 10.5 0.0054 16.6 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CCD25595.1 - 0.0031 17.5 5.9 0.0073 16.3 5.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CCD25595.1 - 0.0064 16.3 10.2 0.012 15.5 10.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCD25595.1 - 0.012 15.5 8.4 0.022 14.7 8.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain QueF_N PF14819.6 CCD25595.1 - 0.082 13.2 0.1 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term zf-C3HC4_3 PF13920.6 CCD25595.1 - 0.11 12.4 10.0 0.18 11.7 10.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sec_GG PF07549.14 CCD25595.1 - 0.17 11.4 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-HC5HC2H PF13771.6 CCD25595.1 - 0.34 11.2 6.5 0.83 10.0 6.5 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.6 CCD25595.1 - 0.49 10.5 8.1 1.2 9.3 8.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Macoilin PF09726.9 CCD25595.1 - 9.2 4.7 22.0 16 3.9 22.0 1.4 1 0 0 1 1 1 0 Macoilin family Malate_synthase PF01274.22 CCD25596.1 - 4.1e-218 724.9 0.0 5e-218 724.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase DCP2 PF05026.13 CCD25597.1 - 8.8e-24 83.7 2.3 1.1e-23 83.3 0.5 2.3 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 CCD25597.1 - 1.9e-12 47.4 0.0 6.2e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 NUDIX domain Consortin_C PF15281.6 CCD25597.1 - 2.9 7.9 6.9 20 5.2 1.5 3.4 2 0 0 2 2 2 0 Consortin C-terminus AAA_assoc_2 PF16193.5 CCD25597.1 - 5 7.5 5.8 20 5.6 0.3 3.8 3 1 1 4 4 4 0 AAA C-terminal domain RcpC PF16976.5 CCD25597.1 - 7.9 6.6 15.3 0.052 13.6 5.0 2.7 3 0 0 3 3 3 0 Flp pilus assembly protein RcpC/CpaB CTU2 PF10288.9 CCD25598.1 - 1.6e-20 73.4 1.5 2.6e-20 72.7 0.0 2.1 3 0 0 3 3 3 1 Cytoplasmic tRNA 2-thiolation protein 2 Zn_Tnp_IS91 PF14319.6 CCD25598.1 - 0.1 12.6 1.2 0.25 11.4 1.2 1.7 1 0 0 1 1 1 0 Transposase zinc-binding domain zinc_ribbon_15 PF17032.5 CCD25598.1 - 0.25 12.1 4.9 0.16 12.8 1.9 2.2 2 0 0 2 2 2 0 zinc-ribbon family TPR_1 PF00515.28 CCD25599.1 - 2.4e-28 96.8 34.4 1.1e-05 25.0 0.4 9.8 9 1 1 10 10 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 CCD25599.1 - 9.9e-28 94.0 36.0 7.8e-05 22.5 0.2 10.9 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.6 CCD25599.1 - 5.1e-19 68.7 3.9 5.8e-05 23.7 0.3 6.2 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CCD25599.1 - 9.8e-16 57.2 26.7 1.7e-05 24.4 0.4 8.3 6 2 2 8 8 8 6 TPR repeat TPR_19 PF14559.6 CCD25599.1 - 1.6e-14 54.2 18.9 1.4e-05 25.5 3.8 6.7 5 2 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 CCD25599.1 - 7.8e-14 51.2 14.5 0.041 14.7 1.7 9.4 7 3 4 11 11 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 CCD25599.1 - 3.5e-13 48.6 29.9 0.0039 17.3 0.2 8.5 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 CCD25599.1 - 2.3e-12 47.0 15.2 0.00059 20.1 0.8 7.5 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCD25599.1 - 3e-11 42.9 8.1 0.0011 19.1 0.2 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD25599.1 - 2e-08 34.3 14.3 0.0077 16.4 0.0 5.0 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 CCD25599.1 - 6.3e-07 29.1 1.0 3.3e-05 23.4 0.5 3.3 4 0 0 4 4 4 1 MalT-like TPR region TPR_9 PF13371.6 CCD25599.1 - 1.8e-06 28.0 0.3 0.18 12.0 0.0 4.8 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCD25599.1 - 5.3e-05 23.0 12.2 0.34 11.0 1.0 6.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_21 PF09976.9 CCD25599.1 - 0.00036 20.3 13.2 0.68 9.6 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat-like domain HrpB1_HrpK PF09613.10 CCD25599.1 - 0.0008 19.0 0.2 1.5 8.5 0.1 3.0 3 0 0 3 3 3 2 Bacterial type III secretion protein (HrpB1_HrpK) Exonuc_VII_S PF02609.16 CCD25599.1 - 0.0023 18.0 2.4 0.0023 18.0 2.4 3.7 5 0 0 5 5 4 1 Exonuclease VII small subunit Sel1 PF08238.12 CCD25599.1 - 0.0041 17.7 0.2 0.73 10.6 0.2 4.1 4 0 0 4 4 3 1 Sel1 repeat Peptidase_S49_N PF08496.10 CCD25599.1 - 0.0048 17.0 2.9 0.0048 17.0 2.9 2.6 3 0 0 3 3 2 1 Peptidase family S49 N-terminal TPR_20 PF14561.6 CCD25599.1 - 0.011 16.1 12.9 0.085 13.2 2.3 4.3 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CCD25599.1 - 0.034 14.0 6.5 2.7 8.0 0.6 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CCD25599.1 - 0.082 13.6 24.7 1.7 9.4 0.5 8.3 11 2 0 11 11 6 0 Tetratricopeptide repeat PEP-utilisers_N PF05524.13 CCD25599.1 - 0.14 12.3 4.7 0.44 10.7 2.0 2.9 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal TPR_4 PF07721.14 CCD25599.1 - 0.7 10.7 3.1 18 6.3 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 CCD25599.1 - 2.9 8.0 8.0 1e+02 3.0 0.0 4.8 3 1 1 4 4 4 0 Domain of Unknown Function (DUF3856) Ribosomal_L35p PF01632.19 CCD25600.1 - 4.8e-13 49.4 5.4 7.6e-13 48.8 5.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 PDZ_1 PF12812.7 CCD25601.1 - 3.8e-54 180.6 0.1 3.6e-35 119.8 0.0 3.6 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.6 CCD25601.1 - 1.4e-24 87.7 0.0 1.3e-20 74.8 0.0 2.4 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 CCD25601.1 - 3.9e-14 52.2 0.4 3.9e-07 29.8 0.1 4.1 5 0 0 5 5 5 2 PDZ domain PDZ_2 PF13180.6 CCD25601.1 - 1.1e-10 41.7 1.8 0.011 16.0 0.2 4.5 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 CCD25601.1 - 4.4e-10 39.8 0.0 6.1e-06 26.5 0.0 2.7 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 CCD25601.1 - 6.7e-06 26.0 0.3 0.026 14.5 0.1 3.6 4 0 0 4 4 4 2 Tricorn protease PDZ domain Trypsin PF00089.26 CCD25601.1 - 0.00021 21.2 0.0 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 1 Trypsin DUF31 PF01732.16 CCD25601.1 - 0.013 15.1 0.1 0.032 13.8 0.1 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.21 CCD25601.1 - 0.13 12.1 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.9 CCD25601.1 - 0.22 10.1 0.0 0.59 8.7 0.0 1.7 2 0 0 2 2 2 0 Peptidase S46 Gar1 PF04410.14 CCD25602.1 - 2e-45 154.3 0.3 2e-45 154.3 0.3 3.3 3 1 1 4 4 4 1 Gar1/Naf1 RNA binding region SOBP PF15279.6 CCD25602.1 - 0.0023 18.6 19.9 0.0023 18.6 19.9 3.0 2 1 1 3 3 3 1 Sine oculis-binding protein GCP_N_terminal PF17681.1 CCD25603.1 - 1.7e-36 126.4 4.6 1.7e-36 126.4 4.6 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CCD25603.1 - 1.4e-28 100.2 3.6 1.4e-28 100.2 3.6 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal N1221 PF07923.13 CCD25604.1 - 7.2e-68 228.9 2.9 1.2e-67 228.1 2.9 1.4 1 0 0 1 1 1 1 N1221-like protein DUF3402 PF11882.8 CCD25604.1 - 7.6e-66 223.1 8.4 8.6e-40 137.2 3.6 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) AD PF09793.9 CCD25605.1 - 8.5e-21 73.9 0.9 1e-20 73.7 0.1 1.5 2 0 0 2 2 2 1 Anticodon-binding domain LSM14 PF12701.7 CCD25605.1 - 0.0091 16.1 0.5 0.014 15.4 0.5 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain DSPc PF00782.20 CCD25606.1 - 8.3e-09 35.4 0.0 2.6e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCD25606.1 - 1.2e-05 25.0 0.2 6.4e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CCD25606.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate AAA_18 PF13238.6 CCD25607.1 - 1.5e-06 28.7 0.8 0.00012 22.6 0.1 2.7 1 1 1 2 2 2 1 AAA domain PRK PF00485.18 CCD25607.1 - 0.0019 18.0 0.1 0.0048 16.7 0.1 1.7 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family tRNA_lig_kinase PF08303.11 CCD25607.1 - 0.0075 16.4 0.5 0.053 13.6 0.0 2.2 2 0 0 2 2 2 1 tRNA ligase kinase domain G-alpha PF00503.20 CCD25607.1 - 0.012 14.9 2.6 0.024 13.8 2.6 1.6 1 1 0 1 1 1 0 G-protein alpha subunit CPT PF07931.12 CCD25607.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 CCD25607.1 - 0.095 12.9 0.3 0.18 12.0 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CCD25607.1 - 0.13 11.9 0.5 0.3 10.8 0.5 1.5 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 CCD25607.1 - 0.14 11.2 0.1 0.24 10.4 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 CCD25607.1 - 0.17 12.1 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain SecE PF00584.20 CCD25608.1 - 3.3e-13 49.3 0.1 4.1e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex MFS_1 PF07690.16 CCD25609.1 - 6.4e-28 97.7 55.1 4.3e-23 81.8 39.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CCD25609.1 - 0.043 12.7 19.2 0.021 13.7 0.7 2.3 2 0 0 2 2 2 0 MFS_1 like family DDHD PF02862.17 CCD25609.1 - 0.94 9.6 3.8 2.4 8.3 3.8 1.7 1 1 0 1 1 1 0 DDHD domain FAM176 PF14851.6 CCD25609.1 - 7.3 6.2 17.1 0.24 11.0 0.1 3.0 3 0 0 3 3 3 0 FAM176 family CDP-OH_P_transf PF01066.21 CCD25610.1 - 4.7e-16 59.3 0.1 4.7e-16 59.3 0.1 3.2 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Tom22 PF04281.13 CCD25611.1 - 6e-50 168.6 2.3 6.8e-50 168.5 2.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 BSMAP PF12280.8 CCD25611.1 - 0.057 13.6 0.2 2.8 8.1 0.1 2.0 1 1 1 2 2 2 0 Brain specific membrane anchored protein DUF4820 PF16091.5 CCD25611.1 - 0.38 10.1 3.6 0.52 9.6 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) GNAT_acetyltr_2 PF13718.6 CCD25612.1 - 2.2e-99 331.5 0.0 2.2e-99 331.5 0.0 2.9 3 0 0 3 3 3 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 CCD25612.1 - 1.3e-91 306.5 11.3 3.7e-91 305.0 11.3 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 CCD25612.1 - 1.2e-65 220.7 0.0 7.4e-65 218.1 0.0 2.4 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 CCD25612.1 - 8.7e-33 112.1 0.4 2.6e-32 110.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 CCD25612.1 - 0.0051 17.1 0.0 0.35 11.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain Sigma70_r4_2 PF08281.12 CCD25612.1 - 0.027 14.2 0.2 1.5 8.6 0.0 2.8 2 0 0 2 2 2 0 Sigma-70, region 4 AAA_19 PF13245.6 CCD25612.1 - 0.027 14.8 0.5 0.72 10.2 0.0 3.2 3 2 0 3 3 3 0 AAA domain DEAD PF00270.29 CCD25612.1 - 0.046 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase Nefa_Nip30_N PF10187.9 CCD25613.1 - 1.8e-10 41.1 17.1 1.8e-10 41.1 17.1 2.0 1 1 1 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Man-6-P_recep PF02157.15 CCD25613.1 - 0.13 11.3 4.8 0.27 10.3 4.8 1.5 1 0 0 1 1 1 0 Mannose-6-phosphate receptor ADH_zinc_N PF00107.26 CCD25614.1 - 1.3e-13 51.1 0.0 2.2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCD25614.1 - 0.00039 20.3 0.2 0.0055 16.6 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CCD25614.1 - 0.0053 17.8 0.0 0.0096 17.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FKBP_C PF00254.28 CCD25615.1 - 1.9e-32 111.4 0.0 2.3e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Eaf7 PF07904.13 CCD25616.1 - 1.4e-37 128.3 7.3 1.4e-37 128.3 7.3 4.4 4 2 0 4 4 4 1 Chromatin modification-related protein EAF7 S4 PF01479.25 CCD25617.1 - 2.8e-16 59.0 0.0 6.1e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 S4 domain LysM PF01476.20 CCD25617.1 - 0.0055 16.7 0.9 0.21 11.7 0.1 3.2 3 0 0 3 3 3 1 LysM domain S4_2 PF13275.6 CCD25617.1 - 0.02 14.7 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 S4 domain CAP_N PF01213.19 CCD25618.1 - 1.2e-110 370.0 6.4 1.6e-110 369.6 6.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 CCD25618.1 - 3.4e-60 202.2 1.7 5.6e-60 201.5 1.7 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DEC-1_N PF04625.13 CCD25618.1 - 0.0079 15.3 1.7 0.0079 15.3 1.7 1.7 2 0 0 2 2 2 1 DEC-1 protein, N-terminal region TBCC PF07986.12 CCD25618.1 - 0.24 11.1 2.1 0.47 10.2 1.4 1.9 2 0 0 2 2 2 0 Tubulin binding cofactor C S-antigen PF05756.11 CCD25619.1 - 0.0062 16.9 0.5 0.0062 16.9 0.5 2.2 2 0 0 2 2 2 1 S-antigen protein WRNPLPNID PF15017.6 CCD25619.1 - 0.072 14.0 0.8 0.21 12.5 0.8 1.8 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box SF3b10 PF07189.11 CCD25620.1 - 4.2e-31 106.9 0.9 5.4e-31 106.5 0.9 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) THOC2_N PF16134.5 CCD25621.1 - 4.6e-176 587.2 20.8 4.6e-176 587.2 20.8 2.6 2 1 1 3 3 3 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 CCD25621.1 - 4.5e-33 114.7 8.7 4.5e-33 114.7 8.7 4.6 4 1 0 4 4 4 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 CCD25621.1 - 1.4e-20 73.1 0.1 4.9e-20 71.4 0.1 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit C2 PF00168.30 CCD25622.1 - 3.9e-07 30.3 0.0 8.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain RNA_pol_3_Rpc31 PF11705.8 CCD25623.1 - 1.7e-54 185.5 19.9 1.7e-54 185.5 19.9 1.9 1 1 1 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 Lipoprotein_6 PF01441.19 CCD25623.1 - 1.6 8.7 9.0 0.27 11.2 5.0 1.6 1 1 1 2 2 2 0 Lipoprotein PGA2 PF07543.12 CCD25624.1 - 3.9e-14 52.8 10.1 3.3e-11 43.3 10.1 2.0 1 1 0 1 1 1 1 Protein trafficking PGA2 DUF1378 PF07125.11 CCD25624.1 - 0.42 10.8 1.4 4.5 7.5 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1378) UPRTase PF14681.6 CCD25625.1 - 2.7e-76 255.6 0.0 3.4e-76 255.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CCD25625.1 - 0.013 15.0 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 CCD25625.1 - 0.17 11.9 0.1 0.29 11.1 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) DUF2009 PF09418.10 CCD25626.1 - 1.1e-207 690.6 4.2 1.4e-207 690.3 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 CCD25626.1 - 1.8e-06 28.0 3.9 3.7e-06 27.0 3.9 1.5 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 CCD25626.1 - 0.0014 18.8 2.5 0.0035 17.5 2.5 1.6 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 CCD25626.1 - 0.013 15.7 2.7 0.033 14.4 2.7 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zinc_ribbon_6 PF14599.6 CCD25626.1 - 0.29 11.2 3.3 0.82 9.7 3.3 1.7 1 0 0 1 1 1 0 Zinc-ribbon Mit_KHE1 PF10173.9 CCD25628.1 - 0.22 11.6 4.9 0.59 10.2 4.9 1.7 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related SURF6 PF04935.12 CCD25628.1 - 9.8 5.9 13.9 0.66 9.7 5.5 2.4 2 0 0 2 2 2 0 Surfeit locus protein 6 CtnDOT_TraJ PF07863.11 CCD25629.1 - 0.1 13.2 2.4 0.25 12.0 2.1 1.8 1 1 1 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon Pga1 PF10333.9 CCD25630.1 - 4.4e-32 111.3 9.4 1.2e-31 109.9 9.4 1.6 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator INSIG PF07281.12 CCD25631.1 - 2.3e-11 43.8 8.8 3.8e-10 39.8 8.8 2.6 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) zf-AN1 PF01428.16 CCD25632.1 - 1.1e-09 38.3 13.5 2.1e-09 37.4 13.5 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Pkinase PF00069.25 CCD25633.1 - 3.1e-28 98.9 0.8 1.1e-27 97.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25633.1 - 2.1e-14 53.4 0.5 4.9e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCD25633.1 - 1.5e-09 37.1 0.0 1.5e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase Prefoldin_2 PF01920.20 CCD25634.1 - 2e-23 82.4 13.4 2.4e-23 82.1 13.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.15 CCD25634.1 - 7.5 6.4 11.6 4.3 7.2 0.5 2.3 1 1 0 2 2 2 0 Septum formation initiator A_deaminase PF00962.22 CCD25635.1 - 5.6e-96 321.7 0.0 6.4e-96 321.5 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Ammonium_transp PF00909.21 CCD25636.1 - 2.8e-126 421.4 27.0 3.2e-126 421.2 27.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3185 PF11381.8 CCD25636.1 - 0.59 10.2 10.4 21 5.2 0.1 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3185) DUF421 PF04239.12 CCD25637.1 - 0.011 15.5 0.1 0.14 11.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF421) Asparaginase_C PF17763.1 CCD25637.1 - 0.015 15.5 0.6 0.26 11.5 0.0 3.0 3 1 0 3 3 3 0 Glutaminase/Asparaginase C-terminal domain Pkinase PF00069.25 CCD25638.1 - 2.1e-60 204.3 5.9 6.9e-42 143.6 0.1 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25638.1 - 5.6e-25 88.1 8.2 1.7e-20 73.4 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CCD25638.1 - 0.00058 18.9 7.9 0.0049 15.9 7.9 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CCD25638.1 - 0.00076 18.9 0.3 0.006 16.0 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCD25638.1 - 0.0025 17.8 0.1 0.71 9.8 0.2 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CCD25638.1 - 0.033 13.3 0.1 0.057 12.5 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 CCD25638.1 - 0.4 9.4 8.5 0.18 10.5 0.1 2.2 2 0 0 2 2 2 0 Fungal protein kinase Ribosomal_L44 PF00935.19 CCD25639.1 - 3.1e-36 123.7 11.4 4.7e-36 123.1 11.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 zf-tcix PF14952.6 CCD25640.1 - 0.0047 16.5 5.7 0.27 10.9 5.7 2.2 1 1 0 1 1 1 1 Putative treble-clef, zinc-finger, Zn-binding Lar_restr_allev PF14354.6 CCD25640.1 - 0.0079 16.5 1.7 0.0096 16.3 1.7 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar DNA_ligase_ZBD PF03119.16 CCD25640.1 - 0.015 15.3 2.2 0.053 13.5 2.2 1.9 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain IBR PF01485.21 CCD25640.1 - 0.067 13.4 3.9 0.43 10.8 0.4 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain TRAF6_Z2 PF18048.1 CCD25640.1 - 0.49 10.5 7.8 0.18 11.9 2.0 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 Ogr_Delta PF04606.12 CCD25640.1 - 0.61 10.1 3.5 20 5.3 3.5 2.2 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger GTP_EFTU PF00009.27 CCD25641.1 - 4.1e-58 196.1 0.0 7.4e-58 195.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CCD25641.1 - 4.3e-14 52.3 0.4 1.4e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCD25641.1 - 1.1e-09 38.6 0.1 4.4e-09 36.6 0.0 2.1 2 1 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CCD25641.1 - 9.6e-09 35.2 0.0 3e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 CCD25641.1 - 3.2e-05 23.7 0.0 0.00019 21.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 CCD25641.1 - 0.011 15.8 0.0 0.034 14.2 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Trypan_PARP PF05887.11 CCD25641.1 - 0.095 12.7 6.5 0.18 11.8 6.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) bZIP_1 PF00170.21 CCD25645.1 - 2.5e-07 30.7 2.7 2.5e-07 30.7 2.7 2.4 2 0 0 2 2 2 1 bZIP transcription factor Aft1_OSA PF11785.8 CCD25645.1 - 1.8e-06 28.2 0.8 1.8e-06 28.2 0.8 3.6 3 1 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain Aft1_HRA PF11786.8 CCD25645.1 - 0.0013 19.1 6.1 0.0013 19.1 6.1 3.6 1 1 1 3 3 3 1 Aft1 HRA domain bZIP_2 PF07716.15 CCD25645.1 - 0.014 15.5 4.6 0.014 15.5 4.6 2.4 2 0 0 2 2 2 0 Basic region leucine zipper OmpH PF03938.14 CCD25645.1 - 2.3 8.5 16.8 0.4 11.0 8.9 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 CCD25645.1 - 6.3 6.1 18.1 13 5.0 18.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAA_hydrolase PF01557.18 CCD25646.1 - 2.3e-45 154.9 0.0 3.1e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PS_Dcarbxylase PF02666.15 CCD25647.1 - 3.1e-70 235.8 0.0 6e-70 234.9 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Rota_NS26 PF01525.16 CCD25647.1 - 0.27 11.2 3.1 0.71 9.8 3.1 1.8 1 1 0 1 1 1 0 Rotavirus NS26 ANAPC1 PF12859.7 CCD25648.1 - 1.3e-07 32.2 3.7 1.3e-07 32.2 3.7 3.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 CCD25648.1 - 0.013 15.9 7.0 0.97 10.0 1.0 4.5 4 0 0 4 4 4 0 Proteasome/cyclosome repeat AMPK1_CBM PF16561.5 CCD25649.1 - 3.6e-15 55.9 1.5 4.2e-15 55.7 0.2 1.8 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase RRM_1 PF00076.22 CCD25650.1 - 1.3e-27 95.4 1.1 6.9e-18 64.2 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD25650.1 - 0.0011 19.1 0.4 1.5 9.0 0.0 3.1 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CCD25650.1 - 0.0029 17.6 0.1 0.0077 16.2 0.0 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Orf78 PF06024.12 CCD25651.1 - 0.021 15.1 0.0 0.23 11.8 0.0 2.5 2 0 0 2 2 2 0 Orf78 (ac78) Ribosomal_L22 PF00237.19 CCD25652.1 - 2.2e-22 79.2 0.0 4e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S3_C PF00189.20 CCD25653.1 - 3.2e-23 82.0 0.6 1.7e-22 79.7 0.7 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CCD25653.1 - 6.8e-12 45.0 0.1 3.3e-11 42.8 0.1 2.0 2 0 0 2 2 2 1 KH domain Ras PF00071.22 CCD25654.1 - 6.2e-44 149.4 0.0 2.2e-43 147.7 0.0 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CCD25654.1 - 8.6e-20 71.2 0.2 8.8e-19 67.9 0.0 2.8 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD25654.1 - 1.4e-05 24.6 0.5 0.00023 20.7 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CCD25654.1 - 0.0028 17.2 0.1 0.0087 15.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain adh_short PF00106.25 CCD25655.1 - 5.7e-10 39.0 0.0 1.5e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCD25655.1 - 6.3e-07 29.2 0.0 2e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCD25655.1 - 5.4e-05 23.2 0.0 9.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF21 PF01595.20 CCD25655.1 - 0.74 9.5 0.0 0.74 9.5 0.0 2.3 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain DUF3012 PF11216.8 CCD25655.1 - 7.7 6.6 6.5 0.41 10.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) ANAPC4_WD40 PF12894.7 CCD25656.1 - 2.6e-07 30.8 0.1 0.00034 20.9 0.0 4.1 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCD25656.1 - 1.5e-06 28.8 0.6 3.4 8.7 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat DASH_Dam1 PF08653.10 CCD25656.1 - 0.058 13.2 0.1 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 DASH complex subunit Dam1 Pkinase PF00069.25 CCD25657.1 - 2.2e-43 148.5 0.0 4.3e-43 147.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25657.1 - 4.9e-22 78.4 0.0 7.5e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CCD25657.1 - 0.012 15.2 0.4 1.9 8.1 0.0 2.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ribosomal_L11_N PF03946.14 CCD25658.1 - 1.1e-26 92.5 0.3 1.6e-26 91.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CCD25658.1 - 2.7e-25 88.7 0.4 4.2e-25 88.1 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain UCH PF00443.29 CCD25659.1 - 1e-47 162.8 3.0 1e-47 162.8 3.0 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCD25659.1 - 6.9e-16 58.7 6.1 6.9e-16 58.7 6.1 4.1 2 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Tim17 PF02466.19 CCD25661.1 - 9.5e-37 125.8 3.2 1.2e-36 125.5 3.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CbtA PF09490.10 CCD25661.1 - 0.038 13.7 0.2 9 6.0 0.3 2.1 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Gly-zipper_Omp PF13488.6 CCD25661.1 - 0.43 10.6 5.2 0.38 10.8 0.4 2.2 2 0 0 2 2 2 0 Glycine zipper Telomerase_RBD PF12009.8 CCD25662.1 - 0.068 13.3 0.7 0.24 11.5 0.7 1.9 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain Orf78 PF06024.12 CCD25662.1 - 4.7 7.6 9.8 0.098 13.0 1.8 2.4 3 0 0 3 3 3 0 Orf78 (ac78) Arm PF00514.23 CCD25663.1 - 5.9e-87 283.4 17.0 3.5e-13 49.1 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 CCD25663.1 - 3.1e-27 94.9 10.2 9.5e-27 93.3 10.2 1.9 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 CCD25663.1 - 1.5e-21 75.7 3.0 9.3e-21 73.1 3.8 2.0 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 CCD25663.1 - 1.2e-17 64.0 2.2 8.6e-06 26.1 0.0 6.9 5 3 3 8 8 8 4 HEAT-like repeat HEAT_2 PF13646.6 CCD25663.1 - 2.1e-13 50.4 0.1 0.00072 19.9 0.0 4.8 2 2 3 5 5 5 5 HEAT repeats HEAT PF02985.22 CCD25663.1 - 1.8e-11 43.3 0.2 0.34 11.3 0.0 7.2 7 0 0 7 7 7 2 HEAT repeat Arm_2 PF04826.13 CCD25663.1 - 1.2e-06 28.2 0.2 0.26 10.7 0.0 4.0 3 2 1 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 CCD25663.1 - 8.6e-05 22.6 0.3 1.3 9.1 0.2 3.9 3 1 0 3 3 3 2 V-ATPase subunit H RICTOR_V PF14668.6 CCD25663.1 - 0.00013 22.1 3.9 0.034 14.4 0.0 4.8 5 1 1 6 6 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.20 CCD25663.1 - 0.0011 17.6 1.9 0.022 13.4 0.2 2.8 1 1 0 3 3 3 1 Adaptin N terminal region NopRA1 PF16201.5 CCD25663.1 - 0.0062 16.2 0.0 1.2 8.6 0.0 4.1 2 2 2 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 O-FucT PF10250.9 CCD25663.1 - 0.029 14.1 0.8 0.055 13.2 0.8 1.4 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase DUF3361 PF11841.8 CCD25663.1 - 0.041 13.8 2.2 2.7 7.9 0.0 3.5 3 2 1 4 4 4 0 Domain of unknown function (DUF3361) HEAT_PBS PF03130.16 CCD25663.1 - 0.25 12.1 4.5 19 6.3 0.0 4.8 6 0 0 6 6 4 0 PBS lyase HEAT-like repeat SAPS PF04499.15 CCD25663.1 - 0.61 8.8 6.0 0.14 10.9 0.9 2.3 2 1 1 3 3 3 0 SIT4 phosphatase-associated protein XPC-binding PF09280.11 CCD25663.1 - 9 6.1 9.3 12 5.8 3.2 2.6 2 0 0 2 2 2 0 XPC-binding domain GATase_4 PF13230.6 CCD25665.1 - 9.6e-11 41.1 0.0 2.5e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 CCD25665.1 - 1e-08 35.5 0.0 2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain PS_Dcarbxylase PF02666.15 CCD25665.1 - 0.044 13.3 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase GATase_7 PF13537.6 CCD25665.1 - 0.15 12.0 0.0 0.98 9.3 0.0 2.0 2 0 0 2 2 2 0 Glutamine amidotransferase domain Chitin_synth_1 PF01644.17 CCD25666.1 - 3.3e-68 228.8 0.4 3.3e-68 228.8 0.4 2.1 3 0 0 3 3 3 1 Chitin synthase Chitin_synth_1N PF08407.11 CCD25666.1 - 1.3e-25 89.2 0.1 3.1e-25 87.9 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CCD25666.1 - 3.1e-21 75.6 0.5 1.2e-14 53.9 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CCD25666.1 - 8.9e-11 42.1 9.1 5e-10 39.6 9.1 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CCD25666.1 - 0.00081 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CCD25666.1 - 0.014 15.2 0.0 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CCD25666.1 - 0.15 11.5 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 MapZ_C2 PF18708.1 CCD25667.1 - 0.027 14.8 2.7 0.95 9.8 0.0 3.8 4 0 0 4 4 4 0 MapZ extracellular C-terminal domain 2 SUR7 PF06687.12 CCD25668.1 - 7.8e-36 123.7 13.3 1.1e-35 123.2 13.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family Pyocin_S PF06958.12 CCD25668.1 - 0.057 14.0 0.2 0.093 13.3 0.2 1.3 1 0 0 1 1 1 0 S-type Pyocin Fig1 PF12351.8 CCD25668.1 - 0.55 10.1 6.4 1 9.2 6.4 1.4 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 TadE PF07811.12 CCD25668.1 - 0.9 9.9 0.0 0.9 9.9 0.0 3.5 4 0 0 4 4 4 0 TadE-like protein MGC-24 PF05283.11 CCD25669.1 - 0.092 13.2 0.6 0.13 12.7 0.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CDC37_N PF03234.14 CCD25670.1 - 0.43 11.5 7.7 0.59 11.0 3.3 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding N6_N4_Mtase PF01555.18 CCD25670.1 - 4.3 7.0 10.1 7 6.3 5.1 2.1 1 1 1 2 2 2 0 DNA methylase RRM_1 PF00076.22 CCD25671.1 - 4.3e-17 61.7 0.2 8.1e-13 48.0 0.1 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD25671.1 - 0.081 13.1 0.1 2.2 8.4 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif DUF533 PF04391.12 CCD25672.1 - 0.16 11.5 0.1 0.38 10.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF533) NYD-SP28 PF14772.6 CCD25672.1 - 0.43 10.7 7.8 0.19 11.8 1.7 2.8 2 1 0 2 2 2 0 Sperm tail HIP1_clath_bdg PF16515.5 CCD25672.1 - 4.1 8.1 7.5 0.3 11.7 0.8 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YjeF_N PF03853.15 CCD25673.1 - 2.6e-34 118.6 0.0 3.1e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Endotoxin_C PF03944.14 CCD25673.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 delta endotoxin GBP PF02263.19 CCD25674.1 - 0.54 9.5 7.0 0.036 13.3 2.2 1.5 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain SMK-1 PF04802.15 CCD25675.1 - 2.8e-57 193.7 10.1 2.8e-57 193.7 10.1 3.2 3 0 0 3 3 3 1 Component of IIS longevity pathway SMK-1 adh_short_C2 PF13561.6 CCD25676.1 - 9.8e-45 152.9 0.1 1.2e-44 152.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CCD25676.1 - 9.1e-33 113.4 0.8 1.1e-32 113.0 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CCD25676.1 - 1.7e-09 37.9 0.1 2.3e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CCD25676.1 - 0.012 14.7 0.4 0.016 14.4 0.4 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 CCD25676.1 - 0.078 12.4 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PH_18 PF18469.1 CCD25677.1 - 1.1e-48 164.7 2.8 1.1e-48 164.7 2.8 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain Rtt106 PF08512.12 CCD25677.1 - 1e-29 102.7 2.5 3.2e-29 101.2 0.7 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Rtt106_N PF18215.1 CCD25677.1 - 1e-16 60.4 0.8 2.9e-16 58.9 0.8 1.8 1 0 0 1 1 1 1 Histone chaperone Rtt106 N-terminal domain RIO1 PF01163.22 CCD25678.1 - 5.5e-43 146.8 0.8 8.9e-43 146.1 0.8 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 CCD25678.1 - 2.2e-32 111.1 0.2 5.7e-32 109.8 0.1 1.8 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 CCD25678.1 - 3.2e-07 30.5 0.0 0.028 14.3 0.5 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CCD25678.1 - 4.8e-05 22.8 0.2 0.028 13.8 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CCD25678.1 - 0.015 14.1 0.0 0.015 14.1 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase THOC2_N PF16134.5 CCD25678.1 - 0.037 12.7 0.0 0.037 12.7 0.0 1.7 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus TFIIA PF03153.13 CCD25678.1 - 1.8 8.5 9.5 2.4 8.0 9.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rick_17kDa_Anti PF05433.15 CCD25679.1 - 7.2e-10 38.6 3.4 1.9e-09 37.2 3.4 1.8 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 CCD25679.1 - 0.00025 21.0 0.4 0.00081 19.3 0.4 1.9 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 CCD25679.1 - 0.4 10.4 8.5 1.3 8.8 8.2 2.1 1 1 1 2 2 2 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.9 CCD25679.1 - 3.4 7.9 14.8 0.053 13.6 2.2 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide HSP70 PF00012.20 CCD25680.1 - 3.1e-229 762.1 8.6 3.5e-229 762.0 8.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCD25680.1 - 2.3e-16 59.5 0.5 8.2e-15 54.4 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CCD25680.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CCD25680.1 - 0.029 14.8 4.7 3 8.3 0.1 3.6 3 2 0 3 3 3 0 Cell division protein FtsA KH_1 PF00013.29 CCD25681.1 - 8.5e-07 28.7 0.1 1.9e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 CCD25681.1 - 0.014 15.2 0.9 0.029 14.2 0.1 1.9 2 0 0 2 2 2 0 KH domain Spo12 PF05032.12 CCD25681.1 - 0.26 11.2 1.5 0.55 10.2 1.5 1.5 1 0 0 1 1 1 0 Spo12 family Mrx7 PF10906.8 CCD25682.1 - 1.6e-28 98.7 1.2 1.9e-28 98.5 1.2 1.1 1 0 0 1 1 1 1 MIOREX complex component 7 VID27 PF08553.10 CCD25683.1 - 8.3e-161 534.9 1.7 1.1e-160 534.5 1.7 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 CCD25683.1 - 6.7e-49 166.1 0.2 6.7e-49 166.1 0.2 2.8 3 0 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 CCD25683.1 - 1.1e-31 109.3 1.1 4e-30 104.3 0.3 2.7 2 0 0 2 2 2 1 VID27 PH-like domain Neugrin PF06413.11 CCD25684.1 - 2.8e-09 37.3 0.3 5.1e-09 36.5 0.3 1.4 1 0 0 1 1 1 1 Neugrin HTH_11 PF08279.12 CCD25684.1 - 3.7e-05 23.6 0.0 0.0021 18.0 0.0 2.4 2 0 0 2 2 2 1 HTH domain Sigma70_r4 PF04545.16 CCD25684.1 - 0.0003 20.2 0.1 0.00054 19.4 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.7 CCD25684.1 - 0.036 13.9 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 CCD25684.1 - 0.079 12.8 0.2 0.86 9.5 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_32 PF13565.6 CCD25684.1 - 0.085 13.5 1.7 0.31 11.7 0.0 2.4 2 1 0 2 2 2 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 CCD25684.1 - 0.098 12.5 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MarR PF01047.22 CCD25684.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 MarR family DUF4019 PF13211.6 CCD25684.1 - 0.12 12.8 0.3 0.12 12.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4019) MRP-L20 PF12824.7 CCD25684.1 - 0.51 10.5 5.3 1.3 9.2 5.1 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 DUF4923 PF16270.5 CCD25685.1 - 0.058 13.2 0.3 0.095 12.5 0.3 1.4 1 0 0 1 1 1 0 Lipocalin-like domain (DUF4923) DUF16 PF01519.16 CCD25685.1 - 0.22 12.1 2.1 0.43 11.1 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 LIM_bind PF01803.16 CCD25686.1 - 1.1e-52 179.0 2.4 1.1e-52 179.0 2.4 2.3 2 0 0 2 2 2 1 LIM-domain binding protein Rap1-DNA-bind PF09197.10 CCD25687.1 - 3e-46 156.5 14.9 6.6e-45 152.1 0.2 3.5 3 0 0 3 3 3 2 Rap1, DNA-binding Rap1_C PF11626.8 CCD25687.1 - 3e-21 75.3 0.0 3e-21 75.3 0.0 2.7 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 CCD25687.1 - 8.3e-19 67.8 1.4 2.9e-18 66.0 0.0 2.7 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-binding PF00249.31 CCD25687.1 - 6.1e-13 48.7 1.3 2.4e-10 40.5 0.0 4.3 5 0 0 5 5 5 1 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 CCD25687.1 - 6.2e-09 35.9 0.2 0.00038 20.6 0.0 3.3 3 0 0 3 3 3 2 Rap1 Myb domain BRCT PF00533.26 CCD25687.1 - 0.037 14.4 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain GREB1 PF15782.5 CCD25687.1 - 0.71 6.9 23.8 0.94 6.5 23.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Metallophos PF00149.28 CCD25688.1 - 2e-08 35.0 1.3 2.9e-08 34.5 1.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MgsA_C PF12002.8 CCD25689.1 - 6.2e-52 175.9 0.9 1.3e-51 174.8 0.1 1.9 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 CCD25689.1 - 1.9e-20 72.9 0.9 6.8e-20 71.2 0.9 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 CCD25689.1 - 1.8e-15 57.6 0.1 5.8e-15 55.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CCD25689.1 - 5e-13 49.1 0.0 3e-11 43.3 0.0 2.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CCD25689.1 - 1.3e-08 34.9 0.0 3.8e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCD25689.1 - 4.9e-07 30.3 0.2 0.00091 19.6 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CCD25689.1 - 2.7e-06 27.7 1.5 3.9e-05 24.0 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CCD25689.1 - 5.8e-06 26.3 0.0 1.9e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 CCD25689.1 - 2.5e-05 23.8 0.0 8.2e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 Bacterial TniB protein Sigma54_activat PF00158.26 CCD25689.1 - 0.0001 22.0 0.0 0.001 18.8 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CCD25689.1 - 0.00042 19.8 0.2 0.047 13.1 0.2 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CCD25689.1 - 0.0012 19.2 0.2 0.31 11.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CCD25689.1 - 0.0093 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 CCD25689.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain hGDE_central PF14702.6 CCD25689.1 - 0.014 15.0 0.5 0.036 13.7 0.1 1.8 2 0 0 2 2 2 0 Central domain of human glycogen debranching enzyme AAA_18 PF13238.6 CCD25689.1 - 0.017 15.7 0.0 0.05 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CCD25689.1 - 0.03 14.8 0.0 0.09 13.3 0.0 1.9 1 1 0 1 1 1 0 ABC transporter ResIII PF04851.15 CCD25689.1 - 0.045 13.8 0.5 0.72 9.8 0.2 2.6 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_2 PF07724.14 CCD25689.1 - 0.048 13.8 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 CCD25689.1 - 0.079 13.4 0.0 0.3 11.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Glyco_transf_22 PF03901.17 CCD25690.1 - 7.3e-89 298.9 31.4 8.7e-89 298.6 31.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family UPF0139 PF03669.13 CCD25690.1 - 0.085 12.7 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) Adenylsucc_synt PF00709.21 CCD25691.1 - 6.8e-178 591.9 0.0 7.7e-178 591.7 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF1033 PF06279.11 CCD25691.1 - 0.26 11.5 0.4 1.1 9.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1033) Ribosomal_L37ae PF01780.19 CCD25692.1 - 5.6e-40 135.3 8.2 6.2e-40 135.2 8.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Rep_fac-A_C PF08646.10 CCD25692.1 - 0.0011 18.8 0.5 0.0012 18.6 0.5 1.2 1 0 0 1 1 1 1 Replication factor-A C terminal domain zf-H2C2_2 PF13465.6 CCD25692.1 - 0.0059 17.0 0.8 1.1 9.8 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 CCD25692.1 - 0.011 15.7 3.1 0.018 15.0 3.1 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Elf1 PF05129.13 CCD25692.1 - 0.024 14.7 1.8 0.038 14.0 1.8 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Sgf11 PF08209.11 CCD25692.1 - 0.059 12.9 1.2 0.41 10.2 0.1 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) C1_2 PF03107.16 CCD25692.1 - 0.12 12.7 2.9 0.33 11.3 2.8 1.7 1 1 0 1 1 1 0 C1 domain CarbpepA_inh PF02977.15 CCD25692.1 - 0.16 11.8 2.8 0.5 10.2 0.3 2.2 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor MRNIP PF15749.5 CCD25692.1 - 0.56 11.0 6.5 14 6.4 2.4 2.4 1 1 2 3 3 3 0 MRN-interacting protein zf-BED PF02892.15 CCD25692.1 - 0.69 10.0 5.3 7.1 6.7 0.4 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C4_ClpX PF06689.13 CCD25692.1 - 1.9 8.5 5.5 6.1 6.8 5.5 2.0 1 1 0 1 1 1 0 ClpX C4-type zinc finger POP1 PF06978.11 CCD25693.1 - 1.3e-77 260.5 12.2 3.4e-77 259.1 12.2 1.8 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 CCD25693.1 - 3.7e-33 113.7 1.2 3.7e-33 113.7 1.2 2.1 2 0 0 2 2 2 1 POPLD (NUC188) domain Ssu72 PF04722.13 CCD25694.1 - 6.1e-84 280.4 0.0 6.8e-84 280.2 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Peptidase_C54 PF03416.19 CCD25695.1 - 4.9e-85 285.3 0.0 6.4e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 G-patch PF01585.23 CCD25696.1 - 1e-09 38.1 3.7 3.2e-09 36.5 3.7 1.9 1 0 0 1 1 1 1 G-patch domain R3H PF01424.22 CCD25696.1 - 0.0039 17.1 0.1 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 R3H domain S4 PF01479.25 CCD25696.1 - 0.15 11.8 0.6 0.45 10.3 0.6 1.9 1 0 0 1 1 1 0 S4 domain SID PF11778.8 CCD25697.1 - 4.3e-43 146.7 1.3 4.3e-43 146.7 1.3 2.8 3 1 0 3 3 3 1 Septation initiation Tropomyosin_1 PF12718.7 CCD25697.1 - 2e-06 28.0 14.8 2e-06 28.0 14.8 3.4 2 1 1 3 3 3 2 Tropomyosin like DUF3584 PF12128.8 CCD25697.1 - 0.093 10.2 31.8 0.21 9.0 16.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) A1_Propeptide PF07966.12 CCD25697.1 - 0.68 9.9 4.8 0.25 11.2 1.3 2.3 2 0 0 2 2 2 0 A1 Propeptide PEP-utilisers_N PF05524.13 CCD25697.1 - 1.8 8.8 13.3 1.4 9.1 1.6 2.9 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal PilJ PF13675.6 CCD25697.1 - 2.1 8.4 5.1 1.6 8.8 0.9 2.7 2 2 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term SIKE PF05769.11 CCD25697.1 - 4.2 7.3 35.8 1.3 8.9 12.5 3.3 2 1 1 3 3 3 0 SIKE family DnaJ PF00226.31 CCD25698.1 - 4.7e-25 87.5 0.4 2e-24 85.4 0.4 2.2 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_2 PF12756.7 CCD25698.1 - 1.7e-07 31.5 6.2 0.00038 20.7 0.4 2.9 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CCD25698.1 - 2.8e-07 30.7 7.5 2.8e-07 30.7 7.5 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCD25698.1 - 6.9e-06 26.3 11.5 0.00015 22.1 4.3 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CCD25698.1 - 1.7e-05 25.0 9.4 0.024 15.1 2.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD25698.1 - 3.9e-05 24.1 6.4 0.14 13.1 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger AKAP95 PF04988.12 CCD25698.1 - 0.011 15.9 2.3 0.011 15.9 2.3 3.5 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) RPT PF13446.6 CCD25698.1 - 0.041 13.8 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 A repeated domain in UCH-protein zf-UBP PF02148.19 CCD25698.1 - 0.074 13.4 0.4 2.4 8.5 0.2 2.6 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_6 PF13912.6 CCD25698.1 - 0.4 10.7 10.6 0.11 12.6 4.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 CCD25698.1 - 4.1 8.1 7.8 10 6.9 0.4 3.3 3 0 0 3 3 3 0 FOXP coiled-coil domain GST_C PF00043.25 CCD25699.1 - 3.3e-24 84.9 1.6 4e-24 84.7 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CCD25699.1 - 3.1e-20 72.3 0.0 9.6e-20 70.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CCD25699.1 - 2.9e-10 40.4 0.0 6.3e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CCD25699.1 - 7e-09 35.9 0.0 1.6e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CCD25699.1 - 1.9e-06 28.0 0.0 5.4e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCD25699.1 - 0.0073 16.3 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Endostatin PF06482.11 CCD25699.1 - 1.8 8.0 14.3 2.5 7.5 14.3 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PTPRCAP PF15713.5 CCD25699.1 - 7.7 6.8 12.0 13 6.1 12.0 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Elongin_A PF06881.11 CCD25700.1 - 1.1e-17 64.4 14.0 6.3e-12 45.9 0.1 3.0 2 1 1 3 3 3 2 RNA polymerase II transcription factor SIII (Elongin) subunit A DPPIV_rep PF18811.1 CCD25700.1 - 0.054 13.5 0.4 2.2 8.3 0.1 2.7 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) low complexity region CRAL_TRIO PF00650.20 CCD25701.1 - 1.4e-40 138.7 0.0 2.2e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCD25701.1 - 1.8e-16 60.1 0.2 4.5e-16 58.8 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain EXOSC1 PF10447.9 CCD25702.1 - 1.2e-42 144.9 0.5 1.2e-42 144.9 0.5 1.7 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 Globin PF00042.22 CCD25704.1 - 0.017 15.7 0.0 0.062 13.9 0.0 2.0 1 1 0 1 1 1 0 Globin Med16 PF11635.8 CCD25705.1 - 5.8e-196 652.8 11.7 6.8e-196 652.6 11.7 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 SCA7 PF08313.12 CCD25705.1 - 0.084 12.8 0.0 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 SCA7, zinc-binding domain Ytp1 PF10355.9 CCD25706.1 - 1.1e-58 198.6 23.5 1.5e-56 191.6 23.5 2.6 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) Peptidase_S8 PF00082.22 CCD25707.1 - 1.3e-39 136.2 1.5 1.3e-39 136.2 1.5 1.6 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 CCD25707.1 - 1.5e-25 89.0 1.1 3.2e-25 88.0 1.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_C1_2 PF03051.15 CCD25708.1 - 4.1e-160 533.4 4.3 4.6e-160 533.2 4.3 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 CCD25708.1 - 1.1e-07 32.1 1.2 0.0056 16.8 0.0 2.8 2 1 0 2 2 2 2 Papain family cysteine protease Fe_hyd_lg_C PF02906.14 CCD25709.1 - 1.3e-53 182.2 0.0 2.2e-53 181.5 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain G6PD_C PF02781.16 CCD25710.1 - 1.5e-105 352.6 0.0 1.9e-105 352.2 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CCD25710.1 - 2.8e-60 204.0 0.0 5.9e-60 202.9 0.1 1.5 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain TSC22 PF01166.18 CCD25710.1 - 1.5 9.2 3.5 35 4.8 0.0 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family ATG2_CAD PF13329.6 CCD25711.1 - 9e-33 113.2 0.8 9e-33 113.2 0.8 2.9 3 0 0 3 3 3 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 CCD25711.1 - 8.4e-32 109.4 0.1 2.1e-31 108.1 0.1 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Etmic-2 PF06670.11 CCD25711.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Microneme protein Etmic-2 ANTH PF07651.16 CCD25712.1 - 1.2e-69 234.4 0.0 1.2e-69 234.4 0.0 2.8 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.17 CCD25712.1 - 5.2e-50 169.7 2.6 5.2e-50 169.7 2.6 5.4 3 2 1 4 4 4 2 I/LWEQ domain YkyA PF10368.9 CCD25712.1 - 5.6 6.6 47.5 2 8.1 40.3 2.8 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein SUI1 PF01253.22 CCD25713.1 - 1.5e-26 92.7 0.5 2.1e-26 92.3 0.5 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cir_N PF10197.9 CCD25714.1 - 5.3e-12 45.7 13.3 5.3e-12 45.7 13.3 1.9 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.8 CCD25714.1 - 3.4e-09 37.5 7.3 3.4e-09 37.5 7.3 2.4 1 1 1 2 2 2 1 Pre-mRNA splicing factor NAP PF00956.18 CCD25715.1 - 1.3e-07 31.1 11.0 1.3e-07 31.1 11.0 2.5 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) tRNA-synt_1e PF01406.19 CCD25716.1 - 1.5e-140 467.8 0.9 3.2e-140 466.7 0.9 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CCD25716.1 - 1.4e-08 34.0 1.4 7.2e-06 25.0 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CCD25716.1 - 6.2e-05 21.4 0.0 0.00015 20.2 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 CCD25716.1 - 0.0072 15.3 0.6 0.048 12.6 0.1 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (K) tRNA-synt_1c PF00749.21 CCD25716.1 - 0.26 10.1 4.5 0.49 9.2 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain RNA_pol_I_A49 PF06870.12 CCD25717.1 - 6.4e-123 410.4 0.4 7.4e-123 410.2 0.4 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Zwint PF15556.6 CCD25717.1 - 0.083 12.4 0.1 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 ZW10 interactor AAA_23 PF13476.6 CCD25718.1 - 2.5e-36 126.1 4.0 2.5e-36 126.1 4.0 9.0 2 1 3 5 5 3 1 AAA domain SMC_N PF02463.19 CCD25718.1 - 1.2e-18 67.4 12.7 1.3e-10 41.1 1.6 4.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain Rad50_zn_hook PF04423.14 CCD25718.1 - 3.4e-16 58.8 0.3 3.4e-16 58.8 0.3 7.1 8 0 0 8 8 8 1 Rad50 zinc hook motif AAA_15 PF13175.6 CCD25718.1 - 2.5e-10 40.6 14.1 2.5e-10 40.6 14.1 5.2 1 1 4 5 5 3 2 AAA ATPase domain AAA_21 PF13304.6 CCD25718.1 - 1.2e-08 35.1 2.9 1.8e-05 24.7 1.8 5.3 3 2 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 CCD25718.1 - 9.9e-07 28.9 0.0 2.6e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 CCD25718.1 - 0.00057 18.7 126.2 0.015 14.0 0.2 8.0 3 1 3 7 7 7 3 AAA domain AAA_29 PF13555.6 CCD25718.1 - 0.00083 19.1 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ERM PF00769.19 CCD25718.1 - 0.0075 16.1 13.6 0.0075 16.1 13.6 5.3 3 2 2 5 5 4 1 Ezrin/radixin/moesin family AAA_16 PF13191.6 CCD25718.1 - 0.03 14.7 0.0 0.03 14.7 0.0 4.0 5 0 0 5 5 5 0 AAA ATPase domain ABC_tran PF00005.27 CCD25718.1 - 0.036 14.6 0.1 0.036 14.6 0.1 8.6 4 3 3 7 7 6 0 ABC transporter AAA_22 PF13401.6 CCD25718.1 - 0.4 11.0 0.0 0.4 11.0 0.0 5.2 4 1 0 4 4 4 0 AAA domain MqsA_antitoxin PF15731.5 CCD25718.1 - 0.4 10.8 4.1 4.8 7.3 0.2 4.3 2 1 1 4 4 4 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Filament PF00038.21 CCD25718.1 - 0.83 9.2 120.6 0.078 12.6 10.6 7.8 1 1 5 7 7 7 0 Intermediate filament protein DUF2937 PF11157.8 CCD25718.1 - 1.2 8.8 4.7 8.5 6.1 0.1 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2937) CTK3 PF12243.8 CCD25719.1 - 3e-05 24.0 0.3 0.00018 21.5 0.1 2.3 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 RRM_1 PF00076.22 CCD25719.1 - 4.7e-05 23.1 0.0 9.9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD25719.1 - 0.0015 18.6 0.1 0.027 14.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif CTD_bind PF04818.13 CCD25719.1 - 0.008 17.0 0.0 0.025 15.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Spo7_2_N PF15407.6 CCD25719.1 - 0.023 14.3 0.0 0.069 12.8 0.0 1.9 1 0 0 1 1 1 0 Sporulation protein family 7 SpoVIF PF14069.6 CCD25719.1 - 0.17 11.7 3.3 6.4 6.6 0.2 3.3 3 0 0 3 3 3 0 Stage VI sporulation protein F MRP-L46 PF11788.8 CCD25720.1 - 3.5e-30 105.2 0.0 5.7e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 WD40 PF00400.32 CCD25721.1 - 1.4e-13 51.0 9.0 6.8e-05 23.6 0.5 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD25721.1 - 6.2e-13 48.9 0.0 0.47 10.8 0.0 5.6 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain MMS1_N PF10433.9 CCD25721.1 - 3.8e-05 22.5 0.1 0.0024 16.6 0.0 3.1 2 2 1 4 4 4 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF5046 PF16465.5 CCD25721.1 - 0.038 13.4 0.0 0.21 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) WD40_like PF17005.5 CCD25721.1 - 0.053 12.8 3.1 0.067 12.5 0.3 2.4 2 2 1 3 3 3 0 WD40-like domain Hira PF07569.11 CCD25721.1 - 0.14 11.8 2.7 14 5.3 0.0 3.2 4 0 0 4 4 4 0 TUP1-like enhancer of split Hyphal_reg_CWP PF11765.8 CCD25722.1 - 2.8e-22 79.1 1.5 4.2e-22 78.5 1.5 1.3 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hyphal_reg_CWP PF11765.8 CCD25723.1 - 3.1e-32 111.8 3.3 3.1e-32 111.8 3.3 1.7 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal Hyphal_reg_CWP PF11765.8 CCD25724.1 - 8.2e-32 110.4 5.7 2e-31 109.1 5.7 1.6 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal RTC4 PF14474.6 CCD25725.1 - 9.6e-29 100.0 0.1 2.1e-28 98.9 0.1 1.6 1 0 0 1 1 1 1 RTC4-like domain zf-CCHC PF00098.23 CCD25726.1 - 6.9e-57 187.1 58.8 4.4e-09 36.0 2.6 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 CCD25726.1 - 6.2e-14 51.5 39.7 0.006 16.3 0.4 7.0 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 CCD25726.1 - 3e-08 33.5 45.5 0.27 11.2 1.0 7.0 2 2 5 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 CCD25726.1 - 7.5e-06 25.6 37.4 0.41 10.4 0.1 7.1 5 2 2 7 7 7 7 GAG-polyprotein viral zinc-finger zf-C2H2_10 PF16588.5 CCD25726.1 - 0.0072 16.0 2.6 0.0072 16.0 2.6 6.6 7 0 0 7 7 7 4 C2H2 zinc-finger zf-CCHC_2 PF13696.6 CCD25726.1 - 0.015 15.1 55.1 0.02 14.7 1.2 6.9 7 0 0 7 7 7 0 Zinc knuckle zf-CCHC_6 PF15288.6 CCD25726.1 - 2.1 8.3 44.4 0.2 11.5 1.4 7.1 7 0 0 7 7 7 0 Zinc knuckle Pterin_bind PF00809.22 CCD25727.1 - 2.5e-53 181.3 0.0 3.1e-52 177.7 0.0 2.2 1 1 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 CCD25727.1 - 7.7e-41 139.1 0.1 5.2e-20 72.1 0.2 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 CCD25727.1 - 2e-33 115.3 0.0 6.9e-33 113.5 0.0 2.0 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) VASt PF16016.5 CCD25728.1 - 3.5e-15 56.7 0.7 1.4e-14 54.7 0.7 2.1 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain PH PF00169.29 CCD25728.1 - 8.1e-11 42.4 3.8 9.7e-11 42.1 0.1 3.1 3 0 0 3 3 3 1 PH domain BAR_3 PF16746.5 CCD25728.1 - 2.1e-09 37.4 1.3 2.1e-09 37.4 1.3 2.1 2 0 0 2 2 2 1 BAR domain of APPL family Gal_mutarotas_2 PF13802.6 CCD25728.1 - 0.087 13.2 0.1 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 Galactose mutarotase-like Dsl1_N PF11988.8 CCD25729.1 - 2.7e-135 450.9 41.4 7.4e-135 449.5 41.4 1.8 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 N terminal Dsl1_C PF11989.8 CCD25729.1 - 1.8e-75 252.9 10.1 1.8e-75 252.9 10.1 3.4 2 1 1 3 3 3 1 Retrograde transport protein Dsl1 C terminal COPI_C PF06957.11 CCD25729.1 - 2.1 7.0 13.0 3.7 6.2 13.0 1.5 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus HMA PF00403.26 CCD25730.1 - 3.3e-11 43.5 0.2 3.9e-11 43.2 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Yae1_N PF09811.9 CCD25731.1 - 1.9e-10 40.3 1.9 2.4e-10 39.9 0.4 1.9 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Syntaxin_2 PF14523.6 CCD25731.1 - 0.041 14.2 1.7 0.059 13.8 1.7 1.3 1 0 0 1 1 1 0 Syntaxin-like protein CLZ PF16526.5 CCD25731.1 - 0.12 12.8 0.8 0.12 12.8 0.8 1.9 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Telomere_reg-2 PF10193.9 CCD25731.1 - 0.14 12.6 0.4 1.5 9.3 0.1 2.1 2 0 0 2 2 2 0 Telomere length regulation protein IL11 PF07400.11 CCD25731.1 - 0.19 11.3 1.1 0.66 9.6 1.1 1.7 1 1 0 1 1 1 0 Interleukin 11 DUF1744 PF08490.12 CCD25732.1 - 4.4e-140 466.8 7.8 8.4e-140 465.9 7.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 CCD25732.1 - 1.1e-77 261.5 4.6 1.1e-77 261.5 4.6 2.7 2 1 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CCD25732.1 - 1.8e-13 50.0 4.4 1.1e-12 47.5 0.6 3.3 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CCD25732.1 - 1.8e-08 34.3 2.1 6.6e-08 32.5 0.4 2.7 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CCD25732.1 - 2.5e-05 24.3 2.1 6.7e-05 22.9 0.0 2.9 2 0 0 2 2 2 1 RNase_H superfamily DUF2181 PF10223.9 CCD25732.1 - 0.025 14.1 0.3 0.054 12.9 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) NAPRTase_C PF17956.1 CCD25732.1 - 0.055 13.9 0.0 0.27 11.7 0.0 2.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain zf-CHY PF05495.12 CCD25732.1 - 3.8 8.1 13.9 12 6.5 13.9 1.9 1 0 0 1 1 1 0 CHY zinc finger Cytochrom_c3_2 PF14537.6 CCD25732.1 - 7.3 7.1 11.3 1.9 9.0 7.4 2.0 2 0 0 2 2 2 0 Cytochrome c3 Cgr1 PF03879.14 CCD25732.1 - 9.3 6.7 8.0 1 9.8 2.2 2.4 2 0 0 2 2 2 0 Cgr1 family YIF1 PF03878.15 CCD25733.1 - 3.5e-77 259.2 5.3 4.2e-77 258.9 5.3 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 CCD25733.1 - 0.02 14.6 8.4 0.047 13.4 8.4 1.7 1 1 0 1 1 1 0 Yip1 domain Mon2_C PF16206.5 CCD25733.1 - 0.098 10.8 0.1 0.13 10.3 0.1 1.1 1 0 0 1 1 1 0 C-terminal region of Mon2 protein CRAL_TRIO PF00650.20 CCD25734.1 - 6.4e-40 136.5 0.0 9.9e-40 135.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCD25734.1 - 1.4e-17 63.6 0.0 2.7e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CCD25734.1 - 0.0014 18.8 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Ist1 PF03398.14 CCD25735.1 - 4.5e-53 179.5 3.4 4.5e-53 179.5 3.4 1.6 2 0 0 2 2 2 1 Regulator of Vps4 activity in the MVB pathway CENP-B_dimeris PF09026.10 CCD25735.1 - 1.9 8.9 8.5 4.5 7.7 8.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PI3_PI4_kinase PF00454.27 CCD25736.1 - 8e-34 117.6 1.5 2.6e-33 115.9 0.0 2.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 CCD25736.1 - 6.1e-19 67.7 0.8 4.2e-18 65.1 0.1 2.6 2 0 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 CCD25736.1 - 1.7e-05 24.3 0.6 4.7e-05 22.9 0.6 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF148 PF02520.17 CCD25736.1 - 0.0021 18.1 1.1 0.01 16.0 1.1 2.2 1 0 0 1 1 1 1 Domain of unknown function DUF148 DUF4135 PF13575.6 CCD25736.1 - 0.03 13.7 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) DUF4949 PF16307.5 CCD25736.1 - 0.52 10.5 3.9 1.5 9.0 3.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4949) AA_permease PF00324.21 CCD25737.1 - 1e-130 436.5 51.8 1.3e-130 436.2 51.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD25737.1 - 2.9e-30 105.5 62.2 4.6e-30 104.8 61.6 1.6 1 1 0 1 1 1 1 Amino acid permease RhodobacterPufX PF11511.8 CCD25737.1 - 0.025 14.2 1.8 1.5 8.4 0.4 3.2 2 0 0 2 2 2 0 Intrinsic membrane protein PufX AA_permease PF00324.21 CCD25738.1 - 4.4e-129 431.2 51.2 5e-129 431.0 51.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD25738.1 - 1.1e-29 103.6 55.4 1.5e-29 103.1 55.4 1.2 1 0 0 1 1 1 1 Amino acid permease YrhC PF14143.6 CCD25738.1 - 1.6 8.9 7.9 1.3 9.2 0.6 3.4 3 0 0 3 3 3 0 YrhC-like protein AA_permease PF00324.21 CCD25739.1 - 1.4e-15 56.8 1.7 1.8e-15 56.5 1.7 1.1 1 0 0 1 1 1 1 Amino acid permease Pet100 PF09803.9 CCD25739.1 - 0.12 12.9 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 Pet100 FH2 PF02181.23 CCD25740.1 - 6.7e-92 308.5 8.0 6.7e-92 308.5 8.0 4.8 2 1 3 5 5 5 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CCD25740.1 - 3.3e-41 141.1 4.3 3.3e-41 141.1 4.3 4.1 4 0 0 4 4 4 2 Diaphanous FH3 Domain Drf_GBD PF06371.13 CCD25740.1 - 2.7e-26 92.3 9.9 2.7e-26 92.3 9.9 5.7 4 3 0 4 4 4 1 Diaphanous GTPase-binding Domain Sec2p PF06428.11 CCD25741.1 - 9e-25 86.5 12.2 9e-25 86.5 12.2 3.3 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p DUF2552 PF10827.8 CCD25741.1 - 0.046 13.9 0.2 0.19 12.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) Rep-A_N PF04057.12 CCD25741.1 - 0.07 13.2 0.1 0.22 11.5 0.1 1.9 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain YfmQ PF10787.9 CCD25741.1 - 0.12 12.1 0.3 0.25 11.1 0.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group ArfGap PF01412.18 CCD25741.1 - 0.16 12.1 2.4 0.42 10.7 0.0 2.9 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf Stimulus_sens_1 PF13756.6 CCD25741.1 - 0.22 12.1 0.1 0.22 12.1 0.1 2.8 2 1 0 2 2 2 0 Stimulus-sensing domain DUF4201 PF13870.6 CCD25741.1 - 1 9.1 27.5 0.15 11.8 8.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TIMELESS PF04821.14 CCD25742.1 - 2.6e-90 302.5 1.9 2.6e-90 302.5 1.9 2.2 3 0 0 3 3 3 1 Timeless protein RNA_bind PF08675.11 CCD25742.1 - 0.14 12.2 0.0 0.42 10.7 0.0 1.8 1 0 0 1 1 1 0 RNA binding domain Hjc PF01870.18 CCD25742.1 - 0.22 11.5 1.4 0.68 10.0 0.3 2.2 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) 2-Hacid_dh_C PF02826.19 CCD25743.1 - 4.7e-54 182.4 0.0 8.1e-54 181.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CCD25743.1 - 5.8e-13 48.7 0.0 7.5e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CCD25743.1 - 0.00015 22.0 0.0 0.00047 20.4 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CCD25743.1 - 0.0047 16.5 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain HCO3_cotransp PF00955.21 CCD25744.1 - 2.9e-78 263.9 14.4 6.5e-40 137.4 3.9 2.2 1 1 1 2 2 2 2 HCO3- transporter family Abhydrolase_1 PF00561.20 CCD25745.1 - 1.5e-70 237.8 0.0 4.1e-70 236.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCD25745.1 - 2.8e-05 24.8 0.0 4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCD25745.1 - 0.055 12.7 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PH PF00169.29 CCD25746.1 - 8e-10 39.2 0.3 1.2e-05 25.7 0.0 2.7 2 0 0 2 2 2 2 PH domain Peptidase_C28 PF05408.11 CCD25747.1 - 0.044 13.5 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase TMEM220 PF15071.6 CCD25747.1 - 0.14 12.9 0.1 0.14 12.9 0.1 3.4 3 1 0 3 3 3 0 Transmembrane family 220, helix EMG1 PF03587.14 CCD25748.1 - 5.4e-77 257.8 0.0 6.3e-77 257.6 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase LCD1 PF09798.9 CCD25749.1 - 5.1e-218 725.5 47.5 7.1e-218 725.1 47.5 1.2 1 0 0 1 1 1 1 DNA damage checkpoint protein Ribosomal_L37e PF01907.19 CCD25750.1 - 2e-27 95.1 11.7 3.5e-27 94.3 11.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 CCD25750.1 - 0.0077 16.2 1.4 0.012 15.7 1.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.18 CCD25750.1 - 0.022 14.9 1.0 0.027 14.5 1.0 1.3 1 1 0 1 1 1 0 SelR domain DUF1258 PF06869.12 CCD25750.1 - 0.94 8.9 4.8 0.57 9.6 3.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) FHA PF00498.26 CCD25751.1 - 0.00017 21.9 0.0 0.0007 19.9 0.0 2.1 1 0 0 1 1 1 1 FHA domain DUF4769 PF15992.5 CCD25751.1 - 0.83 9.4 6.2 5.4 6.7 6.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4769) S-AdoMet_synt_C PF02773.16 CCD25752.1 - 8.8e-65 216.9 0.0 1.6e-64 216.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 CCD25752.1 - 4.6e-45 152.3 0.2 4.6e-45 152.3 0.2 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 CCD25752.1 - 1.4e-44 151.2 0.0 4.1e-44 149.7 0.0 1.8 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 CCD25752.1 - 0.03 13.1 0.1 0.064 12.0 0.0 1.5 1 1 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) PAP2 PF01569.21 CCD25753.1 - 4e-23 81.7 0.6 4e-23 81.7 0.6 1.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CCD25753.1 - 0.0028 17.4 0.3 0.0028 17.4 0.3 2.4 3 0 0 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 CCD25753.1 - 0.041 14.4 5.6 0.041 14.4 5.6 3.1 4 0 0 4 4 4 0 PAP2 superfamily C-terminal PBP1_TM PF14812.6 CCD25753.1 - 0.31 11.5 0.0 0.31 11.5 0.0 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PSP1 PF04468.12 CCD25754.1 - 4.5e-38 129.4 2.2 4.5e-38 129.4 2.2 2.1 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Oxidored_FMN PF00724.20 CCD25755.1 - 8.9e-28 97.5 0.0 9e-26 90.9 0.0 2.2 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AA_permease PF00324.21 CCD25757.1 - 1.9e-128 429.1 37.2 2.4e-128 428.8 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD25757.1 - 4.4e-30 104.8 33.7 5.4e-30 104.6 33.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 CCD25757.1 - 0.18 10.6 0.3 0.41 9.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) SHE3 PF17078.5 CCD25757.1 - 0.2 11.3 5.1 0.31 10.7 5.1 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUP PF00674.18 CCD25758.1 - 8.1e-21 74.1 7.8 4.6e-20 71.7 7.8 2.0 1 1 0 1 1 1 1 DUP family DUF4131 PF13567.6 CCD25758.1 - 0.014 15.1 0.7 0.022 14.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) LapA_dom PF06305.11 CCD25758.1 - 0.015 15.1 0.1 0.015 15.1 0.1 1.9 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF92 PF01940.16 CCD25758.1 - 0.14 11.5 0.2 0.2 11.1 0.2 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF92 La PF05383.17 CCD25759.1 - 1.3e-15 57.1 0.1 2.9e-15 56.1 0.1 1.6 1 0 0 1 1 1 1 La domain LIM_bind PF01803.16 CCD25760.1 - 0.039 13.5 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 LIM-domain binding protein Glutaredoxin PF00462.24 CCD25761.1 - 1.2e-14 54.2 0.0 2.1e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 CCD25761.1 - 0.0014 18.6 0.3 0.0039 17.2 0.2 1.8 1 1 1 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.6 CCD25761.1 - 0.0025 18.0 1.1 1.3 9.1 0.4 2.4 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_9 PF14595.6 CCD25761.1 - 0.0029 17.4 0.2 0.0067 16.2 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CCD25761.1 - 0.0057 17.1 0.0 0.0077 16.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Ribosomal_L33 PF00471.20 CCD25761.1 - 0.015 15.7 1.5 0.023 15.1 1.2 1.6 1 1 0 1 1 1 0 Ribosomal protein L33 TraF PF13728.6 CCD25761.1 - 0.016 15.0 0.2 0.025 14.4 0.2 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein DSBA PF01323.20 CCD25761.1 - 0.02 14.7 0.4 0.27 11.0 0.2 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF836 PF05768.14 CCD25761.1 - 0.039 14.4 0.0 0.057 13.8 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_7 PF13899.6 CCD25761.1 - 0.045 13.9 0.0 0.093 12.9 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.20 CCD25761.1 - 0.053 13.5 0.1 0.064 13.2 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin DUF953 PF06110.11 CCD25761.1 - 0.059 13.0 0.2 0.11 12.1 0.1 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) DUF3128 PF11326.8 CCD25762.1 - 6.5e-27 93.7 2.4 7.4e-27 93.5 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Complex1_LYR_2 PF13233.6 CCD25763.1 - 9e-21 74.4 0.2 1.6e-20 73.7 0.2 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CCD25763.1 - 6.4e-12 45.3 0.0 2.7e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF4028 PF13220.6 CCD25763.1 - 0.016 14.9 0.5 0.064 13.0 0.0 2.1 2 1 0 3 3 3 0 Protein of unknown function (DUF4028) YlbE PF14003.6 CCD25763.1 - 0.12 12.9 1.0 1.5 9.3 0.0 2.5 2 0 0 2 2 2 0 YlbE-like protein Hexokinase_2 PF03727.16 CCD25764.1 - 2e-75 253.3 0.0 2.7e-75 252.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CCD25764.1 - 1.1e-68 231.1 0.0 1.8e-68 230.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase GRASP55_65 PF04495.14 CCD25765.1 - 2.6e-36 125.0 0.0 4.3e-35 121.0 0.0 2.2 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain Thioredoxin PF00085.20 CCD25766.1 - 1.7e-34 117.9 0.0 7.8e-19 67.6 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CCD25766.1 - 1.1e-14 54.8 1.6 1.7e-13 50.9 0.3 3.0 3 1 0 3 3 3 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CCD25766.1 - 0.037 13.4 0.1 0.22 10.9 0.0 2.2 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family FKBP_C PF00254.28 CCD25767.1 - 7.7e-34 115.9 0.0 9.3e-34 115.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Zn_clus PF00172.18 CCD25768.1 - 1.3e-05 25.3 6.1 2.3e-05 24.4 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LOH1CR12 PF10158.9 CCD25768.1 - 0.0067 16.4 0.0 5 7.2 0.0 2.7 2 0 0 2 2 2 2 Tumour suppressor protein ApoA-II PF04711.13 CCD25768.1 - 0.032 14.4 0.3 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) DUF1351 PF07083.11 CCD25768.1 - 0.038 13.8 0.3 0.12 12.2 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) Recep_L_domain PF01030.24 CCD25769.1 - 6.8e-08 32.6 14.8 0.0034 17.5 0.1 4.5 1 1 4 5 5 5 5 Receptor L domain Pkinase PF00069.25 CCD25770.1 - 6.3e-70 235.6 0.0 1e-69 234.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25770.1 - 6.9e-49 166.5 0.0 9.9e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD25770.1 - 1.6e-06 27.6 0.0 0.00046 19.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CCD25770.1 - 6e-06 25.3 0.3 2.5e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase ArfGap PF01412.18 CCD25771.1 - 2.1e-28 98.8 7.0 2.1e-28 98.8 7.0 2.8 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf DUF3446 PF11928.8 CCD25771.1 - 0.012 15.9 1.0 0.012 15.9 1.0 4.2 4 1 0 4 4 4 0 Early growth response N-terminal domain TMV_coat PF00721.21 CCD25771.1 - 0.027 14.3 3.5 0.053 13.4 2.7 2.0 2 0 0 2 2 2 0 Virus coat protein (TMV like) RSF PF14876.6 CCD25772.1 - 3.4e-12 46.0 4.9 3.4e-12 46.0 4.9 2.8 3 1 0 3 3 3 1 Respiratory growth transcriptional regulator DUP PF00674.18 CCD25773.1 - 2e-21 76.1 6.9 7e-21 74.3 6.9 1.9 1 1 0 1 1 1 1 DUP family Herpes_capsid PF06112.11 CCD25774.1 - 0.38 10.8 6.8 0.42 10.7 6.8 1.0 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Pmp3 PF01679.17 CCD25775.1 - 1.4e-20 73.3 8.0 1.6e-20 73.0 8.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RPAP1_C PF08620.10 CCD25776.1 - 4e-27 94.1 0.0 1e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 CCD25776.1 - 6.3e-14 51.5 7.5 6.3e-14 51.5 7.5 2.2 2 0 0 2 2 2 1 RPAP1-like, N-terminal Kre28 PF17097.5 CCD25777.1 - 6e-67 226.2 34.1 7.2e-67 225.9 34.1 1.0 1 0 0 1 1 1 1 Spindle pole body component FAS_N PF17828.1 CCD25777.1 - 0.73 9.8 4.1 1.3 9.0 0.5 2.5 2 0 0 2 2 2 0 N-terminal domain in fatty acid synthase subunit beta Fumble PF03630.14 CCD25778.1 - 2.9e-122 408.0 15.8 4.1e-121 404.2 15.8 2.0 1 1 0 1 1 1 1 Fumble DUF3636 PF12331.8 CCD25778.1 - 0.16 11.8 0.3 2 8.3 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3636) ATP_transf PF09830.9 CCD25779.1 - 4.8e-19 68.3 0.0 7.5e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 CCD25779.1 - 5.3e-06 25.9 0.1 1.5e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4931) DUF4922 PF16269.5 CCD25779.1 - 0.0049 16.7 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4922) UCR_14kD PF02271.16 CCD25780.1 - 8.3e-38 128.4 0.1 9.7e-38 128.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DnaI_N PF07319.11 CCD25782.1 - 0.3 11.8 3.0 1 10.0 0.4 2.8 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus Endonuclease_NS PF01223.23 CCD25783.1 - 2.8e-64 217.0 0.0 3.5e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease RTP1_C1 PF10363.9 CCD25784.1 - 0.036 14.3 1.1 43 4.3 0.0 4.8 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF1676 PF07898.13 CCD25784.1 - 0.04 13.9 3.6 0.058 13.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1676) Sec10 PF07393.11 CCD25785.1 - 2.1e-53 181.9 22.3 2.8e-53 181.5 22.3 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 MMtag PF10159.9 CCD25788.2 - 0.048 13.9 0.3 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 Multiple myeloma tumor-associated ARID PF01388.21 CCD25788.2 - 0.11 13.1 0.0 0.33 11.6 0.0 1.9 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain RRM_1 PF00076.22 CCD25790.2 - 1.2e-07 31.4 0.1 1.9e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CCD25790.2 - 7.1e-07 29.7 3.4 1.2e-06 28.9 3.4 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 CCD25790.2 - 0.019 14.8 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif PUL PF08324.11 CCD25791.2 - 2.1e-42 145.3 0.3 2.8e-42 144.9 0.3 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 CCD25791.2 - 3.6e-39 133.5 0.0 9e-39 132.2 0.0 1.7 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 CCD25791.2 - 1.2e-22 79.7 14.5 0.00059 20.6 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.6 CCD25791.2 - 0.00051 20.1 0.1 1.3 9.1 0.0 4.1 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Mito_carr PF00153.27 CCD25792.2 - 5.9e-49 164.0 2.5 7.8e-19 67.4 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF829 PF05705.14 CCD25792.2 - 0.016 15.1 0.0 0.035 14.0 0.0 1.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) ProSAAS PF07259.12 CCD25792.2 - 0.18 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 ProSAAS precursor DUF2015 PF09435.10 CCD25793.2 - 5.7e-32 109.9 1.1 6.3e-32 109.8 1.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) DUF1837 PF08878.11 CCD25793.2 - 0.083 12.7 0.6 0.1 12.4 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) RRM_1 PF00076.22 CCD25794.2 - 1.8e-58 194.2 0.0 3.4e-20 71.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCD25794.2 - 0.00077 19.1 0.0 1.1 8.8 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD25794.2 - 0.0014 18.7 0.0 0.23 11.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif RRM_Rrp7 PF17799.1 CCD25794.2 - 0.01 15.6 0.0 1.4 8.7 0.0 2.9 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 CCD25794.2 - 0.034 14.1 0.0 8.7 6.4 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CCD25794.2 - 0.16 11.8 0.0 16 5.5 0.0 2.7 3 0 0 3 3 3 0 Occluded RNA-recognition motif Ribosomal_L27_C PF18471.1 CCD25795.2 - 1.1e-92 309.8 24.1 1.4e-92 309.5 24.1 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein C-terminal domain Ribosomal_L27 PF01016.19 CCD25795.2 - 1e-31 108.8 0.1 1.8e-31 108.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein KCH PF16944.5 CCD25796.2 - 6.6e-87 291.4 15.3 8e-87 291.2 15.3 1.1 1 0 0 1 1 1 1 Fungal potassium channel Sedlin_N PF04628.13 CCD25799.2 - 1.3e-09 38.3 0.2 1.5e-09 38.1 0.2 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region FAD_binding_2 PF00890.24 CCD25801.2 - 1.8e-74 251.3 0.0 2.1e-74 251.1 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CCD25801.2 - 1.1e-11 45.0 0.0 3.8e-08 33.3 0.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCD25801.2 - 1.6e-06 28.2 0.0 4.3e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CCD25801.2 - 2.1e-06 27.2 0.8 0.00023 20.5 0.1 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 CCD25801.2 - 4.1e-06 26.2 3.3 3.5e-05 23.2 1.3 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 CCD25801.2 - 2.7e-05 23.2 0.3 0.0081 15.0 0.0 2.1 2 0 0 2 2 2 2 MCRA family Lycopene_cycl PF05834.12 CCD25801.2 - 0.00012 21.3 0.0 0.025 13.6 0.1 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CCD25801.2 - 0.0002 20.7 0.6 0.28 10.4 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CCD25801.2 - 0.00075 18.3 2.4 0.32 9.6 0.1 2.9 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.27 CCD25801.2 - 0.011 16.2 0.3 8.4 7.0 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 CCD25801.2 - 0.012 15.0 0.7 5.9 6.2 0.0 2.7 3 0 0 3 3 3 0 GMC oxidoreductase FAD_oxidored PF12831.7 CCD25801.2 - 0.015 14.7 0.2 0.04 13.3 0.2 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CCD25801.2 - 0.022 14.0 0.0 0.079 12.2 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 CCD25801.2 - 0.047 12.8 0.9 3.8 6.5 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A Mqo PF06039.15 CCD25801.2 - 0.066 11.7 0.8 0.43 9.1 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Amino_oxidase PF01593.24 CCD25801.2 - 0.073 12.3 0.0 0.92 8.7 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 CCD25801.2 - 0.074 13.0 0.1 0.34 10.9 0.1 2.2 1 1 0 1 1 1 0 FAD-NAD(P)-binding YL1_C PF08265.11 CCD25802.2 - 7.9e-14 51.1 0.4 1.4e-13 50.3 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain RseA_C PF03873.13 CCD25802.2 - 0.42 10.9 3.7 0.89 9.8 3.7 1.6 1 1 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain fn3 PF00041.21 CCD25803.2 - 0.00082 19.7 0.1 0.0048 17.2 0.1 2.4 1 0 0 1 1 1 1 Fibronectin type III domain fn3_4 PF16794.5 CCD25803.2 - 0.0063 16.4 0.2 0.026 14.4 0.2 2.2 1 0 0 1 1 1 1 Fibronectin-III type domain SUIM_assoc PF16619.5 CCD25803.2 - 1.6 8.9 10.5 11 6.2 10.5 2.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Lzipper-MIP1 PF14389.6 CCD25803.2 - 4.3 7.7 12.1 0.98 9.8 3.3 3.9 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 GDA1_CD39 PF01150.17 CCD25804.2 - 3.6e-127 424.5 0.0 4.6e-127 424.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 CCD25804.2 - 0.08 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family RNA_pol_Rpb1_4 PF05000.17 CCD25804.2 - 0.11 12.4 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 SR-25 PF10500.9 CCD25804.2 - 7.4 6.1 12.6 11 5.5 12.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NAD_kinase PF01513.21 CCD25805.2 - 3.6e-84 282.4 0.0 6e-84 281.7 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase Glyco_hydro_16 PF00722.21 CCD25806.2 - 2.7e-45 154.0 4.2 2.7e-45 154.0 4.2 2.0 2 1 0 2 2 1 1 Glycosyl hydrolases family 16 SPX PF03105.19 CCD25806.2 - 0.0087 16.0 13.2 0.01 15.8 13.2 1.1 1 0 0 1 1 1 1 SPX domain YcgR_2 PF12945.7 CCD25806.2 - 0.048 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein YcgR RIFIN PF02009.16 CCD25806.2 - 0.16 11.8 2.2 0.24 11.3 2.2 1.3 1 0 0 1 1 1 0 Rifin FAM76 PF16046.5 CCD25806.2 - 2 7.7 14.6 3.1 7.1 14.6 1.2 1 0 0 1 1 1 0 FAM76 protein Apt1 PF10351.9 CCD25806.2 - 3.3 6.4 24.5 4.8 5.9 24.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Chitin_bind_1 PF00187.19 CCD25806.2 - 3.4 8.2 13.2 7.5 7.1 13.2 1.5 1 0 0 1 1 1 0 Chitin recognition protein SOG2 PF10428.9 CCD25806.2 - 4 6.5 28.6 5.3 6.1 28.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein NPR3 PF03666.13 CCD25806.2 - 4.2 6.1 12.6 5.9 5.6 12.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SOBP PF15279.6 CCD25806.2 - 7.1 7.1 15.9 10 6.6 15.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Hid1 PF12722.7 CCD25806.2 - 7.8 4.5 14.0 12 3.9 14.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4614 PF15391.6 CCD25806.2 - 8.2 6.4 32.6 16 5.5 32.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.9 CCD25806.2 - 8.6 4.8 25.3 13 4.2 25.3 1.2 1 0 0 1 1 1 0 Macoilin family GCOM2 PF15328.6 CCD25806.2 - 8.9 6.6 10.2 13 6.0 10.2 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 Cytochrom_C PF00034.21 CCD25807.2 - 2.5e-11 44.5 0.2 4.9e-11 43.6 0.2 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CCD25807.2 - 2.3e-07 31.0 1.2 2e-06 28.0 1.2 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CCD25807.2 - 0.012 15.3 0.2 0.039 13.7 0.1 1.8 2 0 0 2 2 2 0 Cytochrome c-550 domain UBA PF00627.31 CCD25809.2 - 4.2e-29 100.0 6.0 2.1e-15 56.3 1.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 CCD25809.2 - 6e-17 61.2 1.8 7.7e-17 60.8 0.8 1.7 2 0 0 2 2 2 1 Ubiquitin family XPC-binding PF09280.11 CCD25809.2 - 6.5e-10 38.6 1.1 6.5e-10 38.6 1.1 1.8 2 0 0 2 2 1 1 XPC-binding domain Rad60-SLD PF11976.8 CCD25809.2 - 2.3e-07 30.5 1.0 5.6e-07 29.3 1.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CCD25809.2 - 2e-05 24.6 0.1 5.9e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CCD25809.2 - 5.1e-05 23.6 0.7 0.0001 22.6 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 CCD25809.2 - 0.0087 16.6 0.1 0.024 15.2 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain DUF2336 PF10098.9 CCD25809.2 - 0.03 13.8 0.1 0.073 12.5 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) CUE PF02845.16 CCD25809.2 - 0.039 13.7 0.6 3.9 7.3 0.0 4.1 3 2 1 4 4 4 0 CUE domain UBA_3 PF09288.10 CCD25809.2 - 0.042 13.7 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain UBA_2 PF08587.11 CCD25809.2 - 0.07 13.2 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) MCM_N PF14551.6 CCD25809.2 - 0.075 13.6 0.1 0.64 10.6 0.0 2.1 2 0 0 2 2 2 0 MCM N-terminal domain Anp1 PF03452.14 CCD25810.2 - 1.2e-113 378.9 0.0 3.4e-113 377.4 0.0 1.7 2 0 0 2 2 2 1 Anp1 GldH_lipo PF14109.6 CCD25810.2 - 0.018 15.8 0.0 0.039 14.7 0.0 1.5 1 0 0 1 1 1 0 GldH lipoprotein eIF-5a PF01287.20 CCD25811.2 - 5.4e-31 106.5 0.6 7.6e-31 106.0 0.6 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CCD25811.2 - 0.015 15.3 0.1 0.023 14.7 0.1 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain DUF3589 PF12141.8 CCD25812.2 - 3.9e-93 312.7 4.6 1.3e-60 205.4 0.0 2.6 1 1 0 2 2 2 2 Beta-mannosyltransferases SR-25 PF10500.9 CCD25812.2 - 0.57 9.7 16.1 1.2 8.7 16.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MCM PF00493.23 CCD25813.2 - 2.4e-97 324.4 0.1 4.3e-97 323.6 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCD25813.2 - 1.1e-31 109.2 0.0 2.1e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCD25813.2 - 4e-23 81.6 1.0 4e-23 81.6 1.0 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CCD25813.2 - 1.8e-07 30.8 0.0 1.8e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 CCD25813.2 - 2.4e-07 31.3 2.3 9e-07 29.4 0.7 2.8 2 1 0 2 2 2 1 MCM N-terminal domain AAA_3 PF07726.11 CCD25813.2 - 0.0033 17.3 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCD25813.2 - 0.019 14.7 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain E1-E2_ATPase PF00122.20 CCD25814.2 - 8.1e-19 67.8 0.2 2.2e-18 66.4 0.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CCD25814.2 - 1.8e-17 64.4 0.0 6.2e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCD25814.2 - 1.3e-06 28.4 0.0 3.2e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CCD25814.2 - 0.00084 19.2 0.9 0.0055 16.5 0.2 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CCD25814.2 - 0.052 13.1 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Phos_pyr_kin PF08543.12 CCD25815.2 - 3.1e-07 30.1 0.0 4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CCD25815.2 - 1.1e-05 24.9 0.0 2.6e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase RVT_2 PF07727.14 CCD25816.2 - 7e-38 130.6 0.1 2.4e-37 128.9 0.1 1.9 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CCD25816.2 - 4e-13 49.6 0.0 8.5e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CCD25816.2 - 1.1e-05 25.1 0.0 4.6e-05 23.2 0.0 2.1 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF739 PF05339.11 CCD25816.2 - 3.6 7.8 7.7 31 4.8 0.9 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF739) ATP-synt_C PF00137.21 CCD25817.2 - 1.9e-35 121.0 31.1 2.5e-22 79.0 12.4 2.4 2 1 1 3 3 3 2 ATP synthase subunit C Nucleopor_Nup85 PF07575.13 CCD25818.2 - 1.4e-195 651.2 23.8 1.7e-195 650.9 23.8 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin Imm5 PF14423.6 CCD25818.2 - 0.019 15.2 0.8 0.019 15.2 0.8 2.6 2 0 0 2 2 2 0 Immunity protein Imm5 UCR_TM PF02921.14 CCD25819.2 - 7.8e-11 42.3 0.2 2e-10 41.0 0.2 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 CCD25819.2 - 1.3e-10 41.0 0.0 2.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ly49 PF08391.10 CCD25820.2 - 0.11 12.9 12.5 0.075 13.4 4.7 2.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DUF641 PF04859.12 CCD25820.2 - 0.36 11.2 10.0 0.053 13.9 5.1 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF2235 PF09994.9 CCD25821.2 - 1.2e-77 261.2 0.0 2.5e-77 260.0 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Sec7 PF01369.20 CCD25822.2 - 4.3e-67 225.4 0.3 1.1e-66 224.1 0.1 1.9 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 CCD25822.2 - 4.4e-13 49.4 1.2 1.8e-12 47.5 1.2 2.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 CCD25822.2 - 0.00026 20.7 0.6 0.00026 20.7 0.6 3.2 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF2683 PF10884.8 CCD25822.2 - 0.054 13.8 0.5 0.38 11.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) OMPdecase PF00215.24 CCD25823.2 - 8.1e-75 251.3 0.0 9.3e-75 251.1 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family zf-Tim10_DDP PF02953.15 CCD25824.2 - 3.7e-20 71.3 7.5 4.7e-20 71.0 7.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.10 CCD25824.2 - 0.02 15.1 0.1 0.22 11.8 0.0 2.0 1 1 1 2 2 2 0 Phasin protein Tam41_Mmp37 PF09139.11 CCD25824.2 - 0.048 13.1 0.3 0.052 13.0 0.3 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial MFS_1 PF07690.16 CCD25825.2 - 4.2e-23 81.8 14.6 4.2e-23 81.8 14.6 2.7 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCD25825.2 - 3.6e-09 36.0 0.4 3.6e-09 36.0 0.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter COG6 PF06419.11 CCD25826.2 - 4.5e-165 550.4 41.7 4.5e-165 550.4 41.7 1.6 2 1 0 2 2 2 1 Conserved oligomeric complex COG6 Tsc35 PF15079.6 CCD25826.2 - 0.65 9.5 9.4 0.65 9.5 1.5 3.0 3 0 0 3 3 3 0 Testis-specific protein 35 DUF2722 PF10846.8 CCD25827.2 - 1.6e-27 96.7 59.6 3.1e-27 95.7 59.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) TPP_enzyme_N PF02776.18 CCD25828.2 - 2.8e-36 124.7 0.0 6.4e-36 123.5 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCD25828.2 - 3.4e-23 81.9 0.0 5.7e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCD25828.2 - 1.3e-18 67.2 0.1 7.8e-18 64.7 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glycos_transf_1 PF00534.20 CCD25828.2 - 0.061 12.9 0.0 3.2 7.3 0.0 2.6 3 0 0 3 3 3 0 Glycosyl transferases group 1 zf-Nse PF11789.8 CCD25829.2 - 1.4e-20 72.9 1.0 1.8e-20 72.5 0.2 1.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CCD25829.2 - 0.0001 22.2 2.2 0.00022 21.2 2.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 CCD25829.2 - 0.0003 20.2 1.8 0.015 14.7 0.1 2.1 2 0 0 2 2 2 2 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 CCD25829.2 - 0.00062 19.6 0.3 0.0016 18.2 0.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCD25829.2 - 0.0028 18.0 1.3 0.008 16.5 1.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CCD25829.2 - 0.0069 16.2 0.3 0.017 15.0 0.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CCD25829.2 - 0.1 12.6 0.5 0.25 11.4 0.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.20 CCD25829.2 - 0.15 11.8 2.2 0.19 11.5 0.4 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger rve PF00665.26 CCD25831.2 - 8.1e-15 55.1 0.0 1.4e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CCD25831.2 - 0.019 14.8 0.2 0.041 13.7 0.2 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain rve_3 PF13683.6 CCD25831.2 - 0.081 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Pro_CA PF00484.19 CCD25833.2 - 7.5e-34 117.3 0.0 9.7e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Glyco_hydro_15 PF00723.21 CCD25834.2 - 4.3e-49 167.5 0.0 7.9e-49 166.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 eRF1_2 PF03464.15 CCD25834.2 - 0.15 12.4 0.0 0.38 11.1 0.0 1.8 1 0 0 1 1 1 0 eRF1 domain 2 Secretin_N_2 PF07655.13 CCD25834.2 - 9.4 6.9 11.2 0.43 11.1 3.7 2.6 3 0 0 3 3 3 0 Secretin N-terminal domain PIG-H PF10181.9 CCD25835.2 - 1.5e-18 66.5 0.1 2.6e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DUF3139 PF11337.8 CCD25835.2 - 3.4 8.4 13.7 0.11 13.2 5.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3139) rve PF00665.26 CCD25836.2 - 2.1e-15 57.0 0.0 4.6e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 CCD25836.2 - 4.5e-05 23.2 0.1 0.00012 21.9 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain Xrn1_D3 PF18194.1 CCD25836.2 - 0.0065 16.5 1.7 2.6 8.2 0.4 3.0 3 0 0 3 3 3 2 Exoribonuclease 1 Domain-3 rve_3 PF13683.6 CCD25836.2 - 0.037 13.8 0.0 0.095 12.5 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Vps35 PF03635.17 CCD25837.2 - 1.5e-11 43.6 0.1 2.2e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Lambda_CIII PF02061.16 CCD25837.2 - 0.025 14.6 0.0 5.1 7.2 0.1 2.5 2 0 0 2 2 2 0 Lambda Phage CIII Retrotran_gag_2 PF14223.6 CCD25837.2 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Myb_DNA-bind_7 PF15963.5 CCD25838.2 - 5.4e-26 90.3 0.0 5.4e-26 90.3 0.0 3.5 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CCD25838.2 - 3.2e-10 40.0 0.0 1e-09 38.4 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain PulA_N1 PF17999.1 CCD25838.2 - 0.053 14.3 0.3 11 6.8 0.1 3.0 2 0 0 2 2 2 0 Pullulanase N1-terminal domain Myb_DNA-bind_6 PF13921.6 CCD25838.2 - 0.19 12.0 0.1 0.19 12.0 0.1 2.5 3 0 0 3 3 3 0 Myb-like DNA-binding domain WD40 PF00400.32 CCD25839.2 - 6.9e-07 29.9 2.9 0.0044 17.8 0.2 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat UL40 PF10682.9 CCD25839.2 - 0.026 14.2 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 Pkinase PF00069.25 CCD25840.2 - 1.4e-38 132.8 0.1 3.1e-38 131.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25840.2 - 4.8e-29 101.4 0.0 9.6e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD25840.2 - 0.00081 18.8 0.0 0.0018 17.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CCD25840.2 - 0.21 11.5 0.1 1.5 8.7 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Arb2 PF09757.9 CCD25841.2 - 8.4e-98 326.6 0.3 1.2e-97 326.1 0.3 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 CCD25841.2 - 5.6e-88 295.4 0.0 7.7e-88 294.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Methyltr_RsmB-F PF01189.17 CCD25842.2 - 2.8e-21 76.1 0.1 2.6e-14 53.3 0.1 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 CCD25842.2 - 0.018 14.1 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.10 CCD25842.2 - 0.052 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 CCD25842.2 - 0.083 12.0 0.1 0.18 11.0 0.1 1.5 1 0 0 1 1 1 0 O-methyltransferase R3H PF01424.22 CCD25843.2 - 2.5e-20 72.2 0.1 5.2e-20 71.2 0.1 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 CCD25843.2 - 1.2e-10 41.3 55.8 3.9e-06 26.8 15.7 11.5 9 2 1 10 10 10 5 NF-X1 type zinc finger Methyltransf_16 PF10294.9 CCD25844.2 - 1.9e-51 174.3 1.6 6.9e-50 169.2 1.6 2.0 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 CCD25844.2 - 0.094 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF1242 PF06842.12 CCD25845.2 - 5.6e-18 64.4 0.2 7.4e-18 64.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Tim29 PF10171.9 CCD25845.2 - 0.05 13.1 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 Cyclin_N PF00134.23 CCD25846.2 - 4.6e-15 55.5 0.9 1e-14 54.3 0.4 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 CCD25846.2 - 5.1e-07 30.0 0.1 1.2e-06 28.8 0.1 1.7 1 0 0 1 1 1 1 Cyclin C-terminal domain Cyclin_C PF02984.19 CCD25846.2 - 0.0021 18.1 2.2 0.47 10.5 0.0 3.4 3 0 0 3 3 3 2 Cyclin, C-terminal domain Bac_surface_Ag PF01103.23 CCD25847.2 - 1.8e-38 132.8 13.9 2.4e-38 132.4 13.9 1.2 1 0 0 1 1 1 1 Surface antigen zf-C2H2 PF00096.26 CCD25848.2 - 3.8e-13 49.1 12.7 7.6e-07 29.3 1.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD25848.2 - 1.3e-09 38.1 10.4 0.00015 22.3 0.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCD25848.2 - 5.6e-09 36.0 13.1 9.1e-07 29.0 1.0 4.1 4 1 0 4 4 4 3 Zinc-finger double domain zf-met PF12874.7 CCD25848.2 - 6.9e-09 35.8 4.8 7.4e-06 26.2 0.5 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCD25848.2 - 9.1e-09 35.4 7.9 0.00035 20.8 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CCD25848.2 - 1.4e-06 28.1 7.9 0.0024 17.8 0.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_ribbon_recom PF13408.6 CCD25848.2 - 0.0055 17.2 2.8 0.0055 17.2 2.8 2.8 3 0 0 3 3 3 1 Recombinase zinc beta ribbon domain zf_UBZ PF18439.1 CCD25848.2 - 0.081 12.5 7.0 0.47 10.1 0.3 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-BED PF02892.15 CCD25848.2 - 0.21 11.7 7.8 0.84 9.7 0.7 3.3 2 1 1 3 3 3 0 BED zinc finger Met_10 PF02475.16 CCD25849.2 - 2e-10 40.8 0.0 3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 CCD25849.2 - 0.0038 17.0 0.0 0.0074 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CCD25849.2 - 0.04 13.5 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 CCD25849.2 - 0.041 13.3 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 CCD25849.2 - 0.069 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CCD25849.2 - 0.094 13.4 0.0 0.23 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Glyco_transf_15 PF01793.16 CCD25850.2 - 3.1e-84 283.0 26.1 4.8e-53 180.5 13.6 2.1 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase CENP-T_C PF15511.6 CCD25851.2 - 1.8e-09 37.6 0.1 2.2e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CCD25851.2 - 1.4e-05 25.4 0.2 1.7e-05 25.2 0.2 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCD25851.2 - 1.9e-05 24.9 0.1 3.2e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CCD25851.2 - 2.5e-05 24.4 0.1 3.4e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CCD25851.2 - 0.00016 22.0 0.1 0.00022 21.6 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CCD25851.2 - 0.0028 17.7 0.0 0.0034 17.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CCD25851.2 - 0.0093 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 CCD25851.2 - 0.049 14.1 0.0 0.081 13.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 CCD25852.2 - 3.1e-49 166.7 3.4 3.4e-49 166.5 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CCD25852.2 - 2e-06 28.1 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CCD25852.2 - 5.5e-05 23.8 1.3 6.9e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CCD25852.2 - 0.00011 22.3 0.8 0.00015 21.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CCD25852.2 - 0.0018 18.5 0.9 0.0023 18.2 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CCD25852.2 - 0.035 14.2 0.2 0.058 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Y_phosphatase2 PF03162.13 CCD25853.2 - 3.7e-66 221.8 0.1 6.3e-66 221.0 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CCD25853.2 - 6.7e-07 29.5 0.0 8.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CCD25853.2 - 0.001 18.9 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCD25853.2 - 0.0092 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF4301 PF14134.6 CCD25853.2 - 0.042 12.7 0.0 0.07 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) UCH PF00443.29 CCD25854.2 - 2.4e-30 105.9 29.4 1.1e-29 103.8 29.4 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3924 PF13062.6 CCD25854.2 - 0.05 13.5 0.5 0.22 11.5 0.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) OrfB_IS605 PF01385.19 CCD25854.2 - 0.14 12.3 2.9 0.1 12.8 1.0 1.7 2 0 0 2 2 2 0 Probable transposase Frataxin_Cyay PF01491.16 CCD25855.2 - 3.2e-32 110.8 0.0 4.4e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain CPSase_sm_chain PF00988.22 CCD25855.2 - 0.043 13.6 0.1 0.12 12.3 0.1 1.8 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain RE_SinI PF09570.10 CCD25855.2 - 0.065 12.5 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 SinI restriction endonuclease DAHP_snth_FXD PF18152.1 CCD25856.2 - 0.032 14.1 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain BRCT_2 PF16589.5 CCD25856.2 - 0.12 12.8 0.1 0.15 12.5 0.1 1.3 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain ABC_tran PF00005.27 CCD25857.2 - 6.1e-46 156.3 0.0 9.9e-22 77.9 0.0 4.1 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 CCD25857.2 - 1.9e-27 95.2 0.2 5.4e-27 93.7 0.2 1.9 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 CCD25857.2 - 2.8e-19 70.1 0.6 7.7e-05 22.6 0.0 4.9 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCD25857.2 - 7.9e-15 54.9 0.2 5.2e-06 26.1 0.0 4.3 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CCD25857.2 - 6.9e-10 39.8 6.5 0.00032 21.2 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.6 CCD25857.2 - 4.4e-09 36.7 0.0 0.0028 17.9 0.0 4.4 5 0 0 5 5 3 2 AAA domain AAA_29 PF13555.6 CCD25857.2 - 7.2e-09 35.3 0.0 0.0036 17.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCD25857.2 - 4.4e-08 33.2 0.1 0.00047 20.1 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 CCD25857.2 - 5.8e-08 33.1 0.0 0.0023 18.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CCD25857.2 - 7.9e-08 32.4 0.1 0.0022 18.1 0.0 3.4 3 0 0 3 3 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CCD25857.2 - 3.4e-06 27.2 0.0 6.6e-05 23.0 0.0 2.7 2 0 0 2 2 2 1 Dynamin family RNA_helicase PF00910.22 CCD25857.2 - 6e-06 26.6 0.0 0.14 12.5 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 CCD25857.2 - 3.1e-05 24.5 0.0 0.46 11.0 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CCD25857.2 - 4.4e-05 23.7 0.0 0.44 10.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CCD25857.2 - 8.6e-05 23.0 0.0 1.8 9.0 0.0 4.1 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 CCD25857.2 - 0.00011 21.3 0.2 0.29 10.1 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 CCD25857.2 - 0.00014 21.9 0.1 3.6 7.4 0.0 4.0 3 1 0 4 4 4 0 Rad17 P-loop domain DUF87 PF01935.17 CCD25857.2 - 0.0002 21.5 1.4 0.43 10.6 0.0 4.6 4 0 0 4 4 4 1 Helicase HerA, central domain AAA_27 PF13514.6 CCD25857.2 - 0.00034 20.3 0.0 0.32 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 CCD25857.2 - 0.00041 20.2 9.0 0.24 11.1 0.0 4.6 6 0 0 6 6 4 2 AAA ATPase domain AAA_16 PF13191.6 CCD25857.2 - 0.0005 20.5 0.0 0.45 10.9 0.0 3.1 3 0 0 3 3 2 1 AAA ATPase domain AAA_24 PF13479.6 CCD25857.2 - 0.00079 19.2 0.0 1.7 8.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 CCD25857.2 - 0.00089 19.4 0.0 0.73 10.1 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 CCD25857.2 - 0.0011 17.7 0.1 3.8 6.0 0.0 3.5 3 1 0 3 3 3 0 AAA domain NACHT PF05729.12 CCD25857.2 - 0.0012 18.8 0.0 0.95 9.4 0.0 3.0 3 0 0 3 3 3 1 NACHT domain PduV-EutP PF10662.9 CCD25857.2 - 0.0013 18.5 0.0 0.15 11.8 0.0 2.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ParcG PF10274.9 CCD25857.2 - 0.0026 17.9 0.5 6.5 6.8 0.0 3.1 1 1 2 3 3 3 0 Parkin co-regulated protein AAA_14 PF13173.6 CCD25857.2 - 0.0032 17.5 0.0 7.7 6.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 CCD25857.2 - 0.0036 16.9 1.6 2.5 7.6 0.0 3.9 3 1 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CCD25857.2 - 0.0042 16.8 0.2 5.1 6.8 0.1 3.2 4 0 0 4 4 3 0 AAA domain CLASP_N PF12348.8 CCD25857.2 - 0.0046 16.5 2.6 0.014 15.0 1.6 2.2 1 1 1 2 2 2 1 CLASP N terminal MMS19_C PF12460.8 CCD25857.2 - 0.0056 15.8 6.5 1.9 7.5 0.0 3.5 2 1 1 3 3 3 2 RNAPII transcription regulator C-terminal Septin PF00735.18 CCD25857.2 - 0.0064 15.8 1.3 2.9 7.1 0.0 3.4 3 0 0 3 3 3 1 Septin UME PF08064.13 CCD25857.2 - 0.012 15.5 2.0 0.042 13.7 1.3 2.4 3 0 0 3 3 1 0 UME (NUC010) domain Cytidylate_kin PF02224.18 CCD25857.2 - 0.015 15.0 0.0 7.9 6.1 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase Roc PF08477.13 CCD25857.2 - 0.015 15.5 0.0 11 6.2 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase HEAT_2 PF13646.6 CCD25857.2 - 0.016 15.5 0.0 0.42 11.0 0.0 2.9 2 1 2 4 4 4 0 HEAT repeats CLP1_P PF16575.5 CCD25857.2 - 0.017 14.9 0.1 1.9 8.3 0.0 3.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Ploopntkinase3 PF18751.1 CCD25857.2 - 0.018 15.0 0.0 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 G-alpha PF00503.20 CCD25857.2 - 0.029 13.5 0.1 8.5 5.4 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit IstB_IS21 PF01695.17 CCD25857.2 - 0.03 14.1 0.0 5.9 6.6 0.0 3.1 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 CCD25857.2 - 0.039 13.7 0.5 8.4 6.1 0.1 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.21 CCD25857.2 - 0.04 13.3 0.0 2.3 7.6 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CCD25857.2 - 0.04 13.4 0.0 11 5.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 CCD25857.2 - 0.041 13.8 0.8 12 5.7 0.0 3.4 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 CCD25857.2 - 0.044 13.4 0.0 9.6 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain HEAT PF02985.22 CCD25857.2 - 0.044 14.0 0.1 49 4.6 0.0 4.4 4 0 0 4 4 3 0 HEAT repeat MutS_V PF00488.21 CCD25857.2 - 0.066 13.2 0.1 8.2 6.4 0.1 2.5 2 0 0 2 2 2 0 MutS domain V T2SSE PF00437.20 CCD25857.2 - 0.084 11.9 0.0 0.76 8.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.15 CCD25857.2 - 0.084 12.8 0.0 14 5.6 0.0 3.0 3 0 0 3 3 2 0 NTPase Vac14_Fab1_bd PF12755.7 CCD25857.2 - 0.1 13.2 0.1 8.6 7.0 0.0 3.1 2 1 1 3 3 2 0 Vacuolar 14 Fab1-binding region dNK PF01712.19 CCD25857.2 - 0.11 12.3 0.0 9 6.1 0.0 2.8 3 0 0 3 3 2 0 Deoxynucleoside kinase TsaE PF02367.17 CCD25857.2 - 0.12 12.3 0.1 8.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MukB PF04310.12 CCD25857.2 - 0.21 11.4 1.7 15 5.4 0.1 2.9 3 0 0 3 3 3 0 MukB N-terminal PLA2_B PF01735.18 CCD25858.2 - 7.8e-83 278.5 10.5 1.1e-68 231.9 4.5 2.5 2 0 0 2 2 2 2 Lysophospholipase catalytic domain Patatin PF01734.22 CCD25858.2 - 0.0003 21.0 0.0 0.00081 19.6 0.0 1.8 2 1 0 2 2 2 1 Patatin-like phospholipase TetR_C_17 PF17922.1 CCD25858.2 - 0.044 13.9 0.4 4.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain UPF0052 PF01933.18 CCD25859.2 - 3.1e-64 217.0 0.2 4.5e-64 216.5 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 HAD PF12710.7 CCD25860.2 - 8.8e-24 84.9 0.0 1.1e-23 84.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 CCD25860.2 - 1.1e-06 28.3 0.1 1.8e-06 27.5 0.1 1.3 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 CCD25860.2 - 0.00012 21.7 0.0 0.0007 19.2 0.0 2.1 1 1 2 3 3 3 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.6 CCD25860.2 - 0.00014 22.0 0.1 0.0084 16.2 0.1 2.4 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCD25860.2 - 0.00035 20.9 0.3 0.033 14.5 0.0 2.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1947 PF09183.10 CCD25860.2 - 0.053 13.8 0.6 0.13 12.5 0.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1947) Iso_dh PF00180.20 CCD25861.2 - 4.8e-65 220.0 0.1 5.6e-65 219.8 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase QRPTase_C PF01729.19 CCD25863.2 - 4.6e-58 195.7 0.0 5.7e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 CCD25863.2 - 2.1e-17 63.0 0.0 1.6e-16 60.2 0.0 2.4 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Proteasome PF00227.26 CCD25865.2 - 5.2e-58 195.7 0.2 6.5e-58 195.4 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCD25865.2 - 4.3e-12 45.5 1.2 8.2e-12 44.6 0.2 2.1 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature DUF4823 PF16105.5 CCD25865.2 - 0.068 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4823) CNOT11 PF10155.9 CCD25866.2 - 0.036 14.2 0.1 0.15 12.2 0.1 2.2 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 11 UQ_con PF00179.26 CCD25867.2 - 1.3e-35 122.1 0.4 1.5e-35 121.9 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 CCD25867.2 - 7.9e-06 25.6 0.2 1.1e-05 25.1 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 CCD25867.2 - 0.0038 17.5 0.1 0.005 17.1 0.1 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CCD25867.2 - 0.013 15.2 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 CCD25867.2 - 0.07 13.0 0.4 0.11 12.4 0.4 1.3 1 0 0 1 1 1 0 UEV domain Band_7 PF01145.25 CCD25868.2 - 5.2e-25 88.5 2.2 9.9e-25 87.6 2.2 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CCD25868.2 - 0.038 13.1 1.2 0.052 12.6 1.2 1.2 1 0 0 1 1 1 0 SigmaW regulon antibacterial Band_7_1 PF13421.6 CCD25868.2 - 0.08 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family MARVEL PF01284.23 CCD25869.2 - 1.6e-24 86.6 11.5 2e-24 86.2 11.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain SYF2 PF08231.12 CCD25871.2 - 7.5e-10 39.4 21.3 7.5e-10 39.4 21.3 2.0 2 0 0 2 2 2 1 SYF2 splicing factor FYVE_2 PF02318.16 CCD25871.2 - 0.076 13.2 2.3 0.18 12.0 2.3 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Ago_N_1 PF18351.1 CCD25871.2 - 0.34 11.4 13.9 0.28 11.6 1.0 3.1 2 1 1 3 3 3 0 Fungal Argonaute N-terminal domain Utp8 PF10395.9 CCD25872.2 - 2.5e-234 779.8 44.6 3e-234 779.6 44.6 1.0 1 0 0 1 1 1 1 Utp8 family TANGO2 PF05742.12 CCD25873.2 - 3.2e-56 191.2 0.0 3.8e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Sulfate_transp PF00916.20 CCD25875.2 - 1.2e-79 267.8 28.2 1.9e-79 267.2 28.2 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CCD25875.2 - 4.1e-15 55.5 0.9 1.3e-14 53.9 0.9 1.9 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 CCD25875.2 - 0.093 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain DUF5355 PF17306.2 CCD25876.2 - 3.8e-106 354.9 18.3 4.4e-106 354.7 18.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5355) COG2 PF06148.11 CCD25877.2 - 1.4e-08 34.9 3.8 1.4e-08 34.9 3.8 1.9 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Nup54 PF13874.6 CCD25878.2 - 5.7e-35 120.5 5.3 5.7e-35 120.5 5.3 3.0 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 CCD25878.2 - 1.3e-23 83.6 138.6 4.8e-11 43.4 36.0 5.1 1 1 3 4 4 4 4 Nucleoporin FG repeat region Ribosom_S12_S23 PF00164.25 CCD25879.2 - 7.5e-51 170.5 0.3 9.6e-51 170.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 LisH PF08513.11 CCD25880.2 - 0.0002 21.2 0.0 0.00049 19.9 0.0 1.7 1 0 0 1 1 1 1 LisH WD40 PF00400.32 CCD25880.2 - 1.6 9.7 3.6 97 4.1 0.1 4.8 4 1 0 4 4 4 0 WD domain, G-beta repeat LSM14 PF12701.7 CCD25881.2 - 6.5e-24 83.8 0.1 1.3e-23 82.8 0.1 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 CCD25881.2 - 7.4e-13 49.3 6.0 7.4e-13 49.3 6.0 3.1 3 1 0 3 3 3 1 FDF domain TFIIA PF03153.13 CCD25881.2 - 0.00048 20.2 30.9 0.00062 19.9 30.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SM-ATX PF14438.6 CCD25881.2 - 0.0043 17.2 0.0 0.0092 16.1 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain CDC45 PF02724.14 CCD25881.2 - 0.056 11.7 8.4 0.069 11.4 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein FCSD-flav_bind PF09242.11 CCD25881.2 - 4.9 7.6 6.2 25 5.3 0.9 2.7 1 1 1 2 2 2 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding Macoilin PF09726.9 CCD25881.2 - 5.6 5.4 17.9 7 5.1 17.9 1.1 1 0 0 1 1 1 0 Macoilin family DASH_Dam1 PF08653.10 CCD25882.2 - 2e-25 88.3 1.2 6.8e-25 86.6 0.2 2.3 2 0 0 2 2 2 1 DASH complex subunit Dam1 DUF1192 PF06698.11 CCD25882.2 - 0.15 12.1 3.5 0.41 10.7 3.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Sas6_CC PF18594.1 CCD25882.2 - 0.4 10.5 2.1 1 9.2 2.1 1.7 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain SURF1 PF02104.15 CCD25883.2 - 1.4e-45 155.7 0.1 2e-45 155.2 0.1 1.2 1 0 0 1 1 1 1 SURF1 family ig PF00047.25 CCD25883.2 - 0.005 17.0 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin domain Acetyltransf_7 PF13508.7 CCD25884.2 - 0.0083 16.5 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Abhydrolase_1 PF00561.20 CCD25885.2 - 3.6e-21 76.0 2.2 5.9e-21 75.3 2.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCD25885.2 - 2.4e-13 51.2 0.0 3.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCD25885.2 - 8.5e-08 31.7 0.0 2.2e-06 27.2 0.0 2.6 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 CCD25885.2 - 4.6e-06 26.6 0.0 9.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Ndr PF03096.14 CCD25885.2 - 0.013 14.2 0.0 0.028 13.1 0.0 1.5 1 1 0 1 1 1 0 Ndr family DUF2034 PF10356.9 CCD25885.2 - 0.026 14.0 0.1 0.89 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2034) LIDHydrolase PF10230.9 CCD25885.2 - 0.062 12.8 0.1 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase AbLIM_anchor PF16182.5 CCD25885.2 - 0.2 11.4 1.5 0.35 10.6 0.8 1.6 2 0 0 2 2 2 0 Putative adherens-junction anchoring region of AbLIM Cyclin_N PF00134.23 CCD25886.2 - 2.6e-40 137.1 2.1 3.8e-40 136.6 0.4 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCD25886.2 - 1.3e-18 67.2 0.3 3e-18 66.0 0.2 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain BTV_NS2 PF04514.12 CCD25886.2 - 0.093 11.5 0.0 0.093 11.5 0.0 1.6 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Cyclin_N PF00134.23 CCD25887.2 - 2.8e-43 146.7 3.8 7e-41 138.9 0.2 3.3 3 0 0 3 3 3 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCD25887.2 - 4.2e-31 107.5 0.4 1.3e-30 105.9 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF416 PF04222.12 CCD25887.2 - 0.015 14.7 0.1 0.04 13.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF416) GLEYA PF10528.9 CCD25888.2 - 4.5e-42 142.4 6.9 1.8e-22 79.6 0.3 3.4 2 0 0 2 2 2 2 GLEYA domain PA14 PF07691.12 CCD25888.2 - 1.8e-28 99.2 0.2 2e-15 56.9 0.0 2.8 2 0 0 2 2 2 2 PA14 domain TMEM154 PF15102.6 CCD25889.2 - 0.048 13.6 2.8 0.33 10.9 0.1 2.4 2 0 0 2 2 2 0 TMEM154 protein family Orf78 PF06024.12 CCD25889.2 - 0.13 12.6 0.9 0.23 11.7 0.1 1.9 2 0 0 2 2 2 0 Orf78 (ac78) PBP_dimer PF03717.15 CCD25889.2 - 0.21 11.9 3.9 10 6.4 1.1 2.2 2 0 0 2 2 2 0 Penicillin-binding Protein dimerisation domain ATP-synt_S1 PF05827.12 CCD25889.2 - 0.39 10.5 7.1 1 9.2 7.1 1.9 1 1 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) VMA21 PF09446.10 CCD25890.2 - 1.8e-10 40.8 16.2 1.9e-09 37.5 16.2 1.9 1 1 0 1 1 1 1 VMA21-like domain DUF1430 PF07242.11 CCD25890.2 - 0.046 14.0 1.2 0.052 13.8 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) LptF_LptG PF03739.14 CCD25890.2 - 0.11 11.3 2.6 0.12 11.2 2.6 1.0 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Med18 PF09637.10 CCD25891.2 - 6.7e-54 183.4 1.4 7.5e-54 183.2 1.4 1.0 1 0 0 1 1 1 1 Med18 protein Pescadillo_N PF06732.11 CCD25892.2 - 2.7e-83 279.7 0.2 2.7e-83 279.7 0.2 2.3 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 CCD25892.2 - 3.7e-11 43.3 0.0 1.6e-10 41.2 0.0 2.2 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CCD25892.2 - 0.059 13.7 0.0 0.46 10.8 0.0 2.6 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Rhomboid PF01694.22 CCD25894.2 - 1.5e-31 109.4 17.7 2.8e-31 108.6 17.7 1.4 1 0 0 1 1 1 1 Rhomboid family Adeno_hexon PF01065.19 CCD25894.2 - 0.83 8.4 4.0 1.1 8.1 4.0 1.1 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain RabGAP-TBC PF00566.18 CCD25895.2 - 2.1e-49 168.1 0.3 2.1e-49 168.1 0.3 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 CCD25895.2 - 4.4e-16 58.8 0.1 1.4e-15 57.1 0.1 1.9 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 CCD25895.2 - 3.3e-05 23.5 0.9 0.012 15.4 0.1 3.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CCD25895.2 - 0.00043 20.7 1.1 0.38 11.2 0.2 3.1 2 0 0 2 2 2 2 EF-hand domain pair DUF5595 PF18077.1 CCD25895.2 - 0.058 13.5 0.5 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Vps36_ESCRT-II PF11605.8 CCD25895.2 - 0.059 13.6 0.1 0.22 11.8 0.1 2.0 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 EF-hand_1 PF00036.32 CCD25895.2 - 0.066 12.8 0.3 0.26 10.9 0.1 2.2 2 0 0 2 2 2 0 EF hand Gam PF06064.11 CCD25895.2 - 0.077 13.2 0.0 0.28 11.4 0.0 1.9 1 0 0 1 1 1 0 Host-nuclease inhibitor protein Gam PH_TFIIH PF08567.11 CCD25895.2 - 0.11 12.9 0.0 0.92 9.9 0.0 2.3 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain Telomere_reg-2 PF10193.9 CCD25896.2 - 1.8e-24 86.3 0.4 5.2e-24 84.8 0.4 1.8 1 0 0 1 1 1 1 Telomere length regulation protein Peptidase_C50 PF03568.17 CCD25897.2 - 2.2e-132 441.9 0.6 2.2e-132 441.9 0.6 2.8 3 0 0 3 3 3 1 Peptidase family C50 CHAT PF12770.7 CCD25897.2 - 0.014 14.8 0.0 0.037 13.4 0.0 1.7 1 0 0 1 1 1 0 CHAT domain HBD PF18534.1 CCD25897.2 - 0.033 14.3 1.1 7.9 6.7 0.1 4.0 3 0 0 3 3 3 0 Helical bundle domain DUF2833 PF11090.8 CCD25897.2 - 0.088 13.2 0.2 0.87 10.0 0.2 2.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) Flavin_Reduct PF01613.18 CCD25898.2 - 7.7e-31 107.2 0.0 1.2e-30 106.6 0.0 1.3 1 1 0 1 1 1 1 Flavin reductase like domain Mito_carr PF00153.27 CCD25900.2 - 2.9e-58 193.8 2.4 7.1e-20 70.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CCD25900.2 - 0.021 14.0 0.6 0.17 11.0 0.2 2.2 1 1 1 2 2 2 0 Gammaproteobacterial serine protease RNase_PH PF01138.21 CCD25901.2 - 2.1e-17 63.9 0.0 4.3e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CCD25901.2 - 5.5e-06 26.3 0.4 1.1e-05 25.3 0.4 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 tRNA-synt_1 PF00133.22 CCD25902.2 - 2e-220 733.1 1.1 2.5e-219 729.5 1.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CCD25902.2 - 1.4e-25 90.0 1.7 4.5e-25 88.4 1.7 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CCD25902.2 - 1.2e-15 57.1 2.4 1.2e-06 27.6 0.0 4.6 3 2 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CCD25902.2 - 7.1e-10 38.7 0.0 1.3e-06 28.1 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 CCD25902.2 - 1.5e-06 28.4 5.4 3.9e-06 27.0 5.4 1.8 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 CCD25902.2 - 0.02 14.2 1.0 0.53 9.6 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain Peptidase_S24 PF00717.23 CCD25902.2 - 0.11 12.5 0.6 1.2 9.2 0.0 3.0 4 0 0 4 4 4 0 Peptidase S24-like ABC_tran_CTD PF16326.5 CCD25902.2 - 0.27 11.5 2.1 0.7 10.2 2.1 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 CCD25902.2 - 8.8 6.4 8.2 2.5 8.1 4.4 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CwfJ_C_1 PF04677.15 CCD25903.2 - 2.3e-31 108.2 3.8 3.2e-31 107.7 0.7 2.6 2 1 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CCD25903.2 - 3.4e-18 66.3 1.0 9.5e-18 64.9 1.0 1.8 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 LMP PF04778.12 CCD25903.2 - 4.6 7.1 9.6 2 8.3 0.2 3.7 4 0 0 4 4 4 0 LMP repeated region Pkinase PF00069.25 CCD25904.2 - 4e-56 190.3 0.0 1.8e-55 188.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25904.2 - 8.8e-28 97.3 0.1 8.9e-20 71.0 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CCD25904.2 - 0.00027 20.0 0.4 0.00057 18.9 0.4 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 CCD25904.2 - 0.003 18.2 0.9 0.0068 17.1 0.9 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.14 CCD25904.2 - 0.0041 16.5 0.0 0.009 15.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCD25904.2 - 0.0046 16.3 0.0 0.063 12.6 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CCD25904.2 - 0.11 12.5 0.0 0.51 10.2 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nop PF01798.18 CCD25905.2 - 1.4e-65 221.0 4.3 2.2e-65 220.4 4.3 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CCD25905.2 - 2.2e-25 89.9 3.3 2.2e-25 89.9 3.3 2.2 2 0 0 2 2 2 1 Prp31 C terminal domain Nrap_D5 PF17406.2 CCD25906.2 - 6.6e-53 178.8 0.0 1.9e-52 177.3 0.0 1.8 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 CCD25906.2 - 6.1e-51 172.8 0.2 1.1e-50 172.0 0.2 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 CCD25906.2 - 1.9e-47 160.8 2.1 3.6e-46 156.7 0.3 2.9 3 0 0 3 3 3 1 Nrap protein PAP/OAS-like domain Nrap PF03813.14 CCD25906.2 - 1e-44 152.2 4.1 1e-44 152.2 4.1 2.6 3 0 0 3 3 3 1 Nrap protein domain 1 Nrap_D3 PF17404.2 CCD25906.2 - 3.3e-39 134.5 0.0 7.3e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 CCD25906.2 - 4.9e-29 101.3 0.1 1.5e-28 99.7 0.1 1.9 1 0 0 1 1 1 1 Nrap protein domain 6 DUF4611 PF15387.6 CCD25906.2 - 0.32 11.2 7.2 0.71 10.1 7.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NPM1-C PF16276.5 CCD25907.2 - 0.69 9.9 5.3 1.4 9.0 0.0 3.7 3 0 0 3 3 3 0 Nucleophosmin C-terminal domain Catalase PF00199.19 CCD25908.2 - 6.2e-161 535.8 1.2 1.8e-160 534.2 1.2 1.7 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CCD25908.2 - 1.1e-12 47.9 0.0 2.7e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF2111 PF09884.9 CCD25908.2 - 0.079 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) Pil1 PF13805.6 CCD25909.2 - 1e-122 408.8 0.2 1.6e-122 408.1 0.2 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 SLT_beta PF02258.16 CCD25909.2 - 0.11 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Shiga-like toxin beta subunit CDC45 PF02724.14 CCD25909.2 - 0.88 7.8 12.3 1 7.5 12.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DHHC PF01529.20 CCD25910.2 - 4.7e-37 127.1 15.1 4.7e-37 127.1 15.1 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase BPD_transp_1 PF00528.22 CCD25910.2 - 2.4 7.8 10.9 3.5 7.3 4.6 2.3 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component TNFR_16_TM PF18422.1 CCD25910.2 - 2.7 8.0 12.3 0.66 10.0 1.6 2.9 3 0 0 3 3 3 0 Tumor necrosis factor receptor member 16 trans-membrane domain Porph_ging PF09697.10 CCD25911.2 - 0.12 12.9 0.8 4.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) STN1_2 PF09170.10 CCD25911.2 - 8.7 6.5 9.7 1.2 9.3 0.4 3.4 2 1 1 3 3 3 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Pam16 PF03656.13 CCD25912.2 - 0.0011 18.9 0.1 0.0015 18.5 0.1 1.2 1 0 0 1 1 1 1 Pam16 Pesticin PF16754.5 CCD25912.2 - 0.02 14.8 0.1 0.28 11.2 0.1 2.1 1 1 1 2 2 2 0 Bacterial toxin homologue of phage lysozyme, C-term DnaJ PF00226.31 CCD25912.2 - 0.024 14.8 0.1 0.048 13.8 0.1 1.5 1 0 0 1 1 1 0 DnaJ domain AAA PF00004.29 CCD25913.2 - 1.7e-53 180.6 0.0 9.7e-45 152.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CCD25913.2 - 3.8e-06 26.8 0.4 2.3e-05 24.3 0.1 2.6 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 CCD25913.2 - 1.3e-05 24.8 0.0 0.0095 15.7 0.0 3.1 3 0 0 3 3 3 1 AAA+ lid domain AAA_2 PF07724.14 CCD25913.2 - 7.4e-05 22.9 0.0 0.00044 20.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CCD25913.2 - 0.00021 21.1 0.0 0.00066 19.4 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain ANAPC9 PF12856.7 CCD25913.2 - 0.00044 20.4 1.9 0.0032 17.6 0.3 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 9 Parvo_NS1 PF01057.17 CCD25913.2 - 0.0005 19.2 0.1 0.0016 17.6 0.0 1.9 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.6 CCD25913.2 - 0.0012 19.3 0.0 0.11 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 CCD25913.2 - 0.002 17.7 0.0 0.0047 16.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CCD25913.2 - 0.0026 18.1 0.0 0.012 16.0 0.0 2.2 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 CCD25913.2 - 0.0036 17.3 0.0 0.019 14.9 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCD25913.2 - 0.0042 17.4 0.0 0.093 13.0 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 CCD25913.2 - 0.013 16.1 0.0 0.1 13.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain ATPase PF06745.13 CCD25913.2 - 0.017 14.5 0.0 0.041 13.2 0.0 1.6 1 0 0 1 1 1 0 KaiC TIP49 PF06068.13 CCD25913.2 - 0.018 14.3 0.0 0.038 13.2 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 CCD25913.2 - 0.018 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 CCD25913.2 - 0.02 14.9 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CCD25913.2 - 0.024 14.0 0.1 0.047 13.1 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CCD25913.2 - 0.068 13.2 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_pol_Rpb4 PF03874.16 CCD25913.2 - 0.074 13.4 0.3 1.5 9.2 0.0 2.9 2 0 0 2 2 2 0 RNA polymerase Rpb4 AAA_3 PF07726.11 CCD25913.2 - 0.1 12.5 0.0 0.85 9.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CCD25913.2 - 0.23 11.0 0.0 0.69 9.4 0.0 1.7 1 1 1 2 2 2 0 AAA domain ResIII PF04851.15 CCD25913.2 - 0.33 10.9 2.4 4.9 7.1 0.0 2.7 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit Sld5 PF05916.11 CCD25914.2 - 2.4e-17 63.4 0.0 3.2e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein PEX11 PF05648.14 CCD25915.2 - 6.1e-54 182.8 5.3 7.1e-54 182.6 5.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) dsrm PF00035.26 CCD25916.2 - 2.5e-08 34.5 0.0 0.0087 16.7 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif Presenilin PF01080.17 CCD25916.2 - 0.00044 19.1 9.2 0.00079 18.3 9.2 1.4 1 0 0 1 1 1 1 Presenilin PRCC PF10253.9 CCD25916.2 - 0.00097 20.0 4.0 0.00097 20.0 4.0 4.0 2 1 2 4 4 4 1 Mitotic checkpoint regulator, MAD2B-interacting Nop14 PF04147.12 CCD25916.2 - 0.013 13.7 25.1 0.02 13.1 25.1 1.2 1 0 0 1 1 1 0 Nop14-like family Raftlin PF15250.6 CCD25916.2 - 0.038 12.7 11.4 0.071 11.9 11.4 1.4 1 0 0 1 1 1 0 Raftlin Ribonuclease_3 PF00636.26 CCD25916.2 - 0.084 13.5 0.0 0.084 13.5 0.0 3.0 3 1 0 3 3 2 0 Ribonuclease III domain CobT PF06213.12 CCD25916.2 - 0.52 9.7 26.8 1 8.7 26.8 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 CCD25916.2 - 2.3 7.6 35.6 0.013 14.9 26.5 1.8 2 0 0 2 2 2 0 SDA1 SID-1_RNA_chan PF13965.6 CCD25916.2 - 2.6 6.3 5.6 3.8 5.8 5.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RRN3 PF05327.11 CCD25916.2 - 2.7 6.4 13.4 4.8 5.6 13.4 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIA PF03153.13 CCD25916.2 - 3.8 7.4 27.1 7.1 6.5 27.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 CCD25916.2 - 4.8 6.3 9.5 7.5 5.7 9.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Cwf_Cwc_15 PF04889.12 CCD25916.2 - 6.1 6.5 29.0 0.068 12.9 21.2 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SLX9 PF15341.6 CCD25917.2 - 2.3e-23 83.0 14.8 2.3e-23 83.0 14.8 1.5 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 MAS20 PF02064.15 CCD25918.2 - 3.7e-35 120.8 0.8 4.8e-35 120.5 0.8 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor Lip_A_acyltrans PF03279.13 CCD25918.2 - 0.034 13.3 0.0 0.33 10.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial lipid A biosynthesis acyltransferase Pox_A14 PF05767.12 CCD25918.2 - 0.16 12.2 0.1 0.38 11.0 0.0 1.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 RAMP4 PF06624.12 CCD25918.2 - 0.29 11.2 2.1 0.63 10.2 2.1 1.6 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 IF-2B PF01008.17 CCD25919.2 - 1.3e-104 349.4 0.3 1.3e-104 349.4 0.3 1.9 2 0 0 2 2 2 1 Initiation factor 2 subunit family Methyltransf_14 PF08484.11 CCD25919.2 - 0.018 14.9 4.4 1.7 8.4 2.6 2.4 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain NBP1 PF08537.10 CCD25919.2 - 0.025 14.0 22.5 0.13 11.6 0.1 3.2 3 0 0 3 3 3 0 Fungal Nap binding protein NBP1 eIF3_subunit PF08597.10 CCD25919.2 - 3.4 7.5 30.0 0.37 10.7 17.2 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit HlyD PF00529.20 CCD25921.2 - 0.037 13.9 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 HlyD membrane-fusion protein of T1SS DUF4537 PF15057.6 CCD25921.2 - 0.06 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) DUP PF00674.18 CCD25923.2 - 2.3e-20 72.6 3.6 2.3e-20 72.6 3.6 1.6 1 1 1 2 2 2 1 DUP family Syja_N PF02383.18 CCD25924.2 - 3.5e-76 256.6 0.0 3.5e-76 256.6 0.0 2.1 3 0 0 3 3 3 1 SacI homology domain KRE1 PF17056.5 CCD25925.2 - 4.7e-25 87.1 11.6 4.7e-25 87.1 11.6 7.1 4 3 5 9 9 9 1 Killer toxin-resistance protein 1 Na_Ca_ex PF01699.24 CCD25926.2 - 1.1e-17 64.3 34.5 5.1e-15 55.7 13.4 3.5 5 1 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 CCD25926.2 - 1.6e-13 51.1 4.5 1.6e-13 51.1 4.5 4.6 4 0 0 4 4 4 1 Inner membrane component domain Hydrolase_4 PF12146.8 CCD25927.2 - 1.6e-14 53.7 0.0 2.2e-09 37.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCD25927.2 - 2.7e-12 46.9 0.0 1.8e-09 37.6 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CCD25927.2 - 9.2e-06 25.3 0.0 2.3e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 CCD25927.2 - 0.00029 20.6 0.0 0.0004 20.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 CCD25927.2 - 0.00094 19.2 0.0 0.0094 15.9 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 CCD25927.2 - 0.0066 17.1 0.0 0.0082 16.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CCD25927.2 - 0.012 15.4 0.0 1.5 8.6 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 CCD25927.2 - 0.018 14.6 0.0 4.5 6.7 0.1 2.3 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase DUF1749 PF08538.10 CCD25927.2 - 0.026 13.6 0.0 0.038 13.1 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) Esterase PF00756.20 CCD25927.2 - 0.031 13.9 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF818 PF05677.12 CCD25927.2 - 0.031 13.2 0.1 0.055 12.4 0.1 1.3 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 CCD25927.2 - 0.032 13.8 0.0 0.24 10.9 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Sugar_tr PF00083.24 CCD25928.2 - 2e-118 396.1 29.1 2.3e-118 395.9 29.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD25928.2 - 2.9e-27 95.6 28.0 7.9e-24 84.2 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1285 PF06938.11 CCD25928.2 - 0.17 11.9 0.1 0.3 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1285) PDT PF00800.18 CCD25929.2 - 9.6e-37 126.6 0.0 2.1e-36 125.4 0.0 1.5 1 1 0 1 1 1 1 Prephenate dehydratase ATP11 PF06644.11 CCD25930.2 - 1.1e-89 300.8 2.8 1.4e-89 300.6 2.8 1.0 1 0 0 1 1 1 1 ATP11 protein SH3BGR PF04908.15 CCD25930.2 - 0.0063 16.7 0.5 0.015 15.4 0.5 1.6 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Prenyltransf PF01255.19 CCD25931.2 - 7.9e-75 251.2 0.0 9.9e-75 250.9 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Pyrophosphatase PF00719.19 CCD25932.2 - 2.1e-58 196.6 0.3 2.9e-58 196.2 0.3 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase PRAI PF00697.22 CCD25933.2 - 2.1e-54 184.3 0.1 2.4e-54 184.1 0.1 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Histone PF00125.24 CCD25934.2 - 1.9e-49 167.4 3.6 2.1e-49 167.2 3.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CCD25934.2 - 1.9e-06 28.1 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CCD25934.2 - 0.00013 22.1 1.1 0.00014 21.9 0.2 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 CCD25934.2 - 0.00035 21.2 2.5 0.00046 20.8 2.5 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 CCD25934.2 - 0.0017 18.6 0.9 0.0023 18.2 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CCD25934.2 - 0.034 14.2 0.2 0.057 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 CCD25935.2 - 1.8e-09 37.6 0.1 2.2e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CCD25935.2 - 1.4e-05 25.4 0.2 1.7e-05 25.2 0.2 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCD25935.2 - 1.9e-05 24.9 0.1 3.2e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CCD25935.2 - 2.5e-05 24.4 0.1 3.4e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CCD25935.2 - 0.00016 22.0 0.1 0.00022 21.6 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CCD25935.2 - 0.0028 17.7 0.0 0.0034 17.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CCD25935.2 - 0.0093 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 CCD25935.2 - 0.049 14.1 0.0 0.081 13.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Aldo_ket_red PF00248.21 CCD25936.2 - 2.9e-60 204.0 0.0 3.3e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF5600 PF18150.1 CCD25936.2 - 0.1 13.2 0.1 2.1 9.0 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5600) DUF2624 PF11116.8 CCD25936.2 - 0.14 13.1 0.0 16 6.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Tcp11 PF05794.13 CCD25937.2 - 3e-74 250.7 1.4 3e-74 250.7 1.4 1.7 2 0 0 2 2 2 1 T-complex protein 11 Sel1 PF08238.12 CCD25938.2 - 1.4e-10 41.4 2.2 0.00019 22.0 0.0 3.5 3 0 0 3 3 3 3 Sel1 repeat Aldedh PF00171.22 CCD25939.2 - 6.4e-157 522.8 0.0 7.2e-157 522.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CCD25939.2 - 0.00072 19.1 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) Wtap PF17098.5 CCD25939.2 - 0.06 13.3 0.3 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 WTAP/Mum2p family RCR PF12273.8 CCD25940.2 - 1.3e-14 54.9 2.2 1.8e-14 54.4 0.0 2.3 3 0 0 3 3 3 1 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.6 CCD25940.2 - 0.00047 20.1 1.2 0.00092 19.1 0.0 2.0 2 0 0 2 2 2 1 TMEM154 protein family Colicin_V PF02674.16 CCD25940.2 - 0.018 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Colicin V production protein TMEM51 PF15345.6 CCD25940.2 - 0.034 14.0 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 DUF4064 PF13273.6 CCD25940.2 - 0.057 13.7 1.4 0.14 12.5 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF3382 PF11862.8 CCD25940.2 - 0.12 12.7 0.2 0.62 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) PDGLE PF13190.6 CCD25940.2 - 2 8.4 5.1 19 5.2 4.9 2.6 2 1 1 3 3 3 0 PDGLE domain Pilin_N PF07790.11 CCD25940.2 - 2.5 9.1 5.3 4.7 8.2 0.1 2.6 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal DUF3439 PF11921.8 CCD25940.2 - 2.9 7.9 10.4 15 5.6 5.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Pex2_Pex12 PF04757.14 CCD25941.2 - 1.5e-11 44.3 12.4 2.4e-11 43.7 12.4 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region FdhE PF04216.12 CCD25941.2 - 0.011 15.6 1.7 0.018 15.0 1.7 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-C3HC4_3 PF13920.6 CCD25941.2 - 0.15 12.0 8.7 0.27 11.1 8.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCD25941.2 - 2.9 7.9 11.4 9.4 6.3 11.5 1.9 1 1 1 2 2 2 0 zinc-RING finger domain Mannosyl_trans2 PF04188.13 CCD25942.2 - 1.1e-81 275.4 33.7 1e-79 269.0 33.7 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) Ran_BP1 PF00638.18 CCD25943.2 - 1.8e-53 180.0 1.6 1.8e-53 180.0 1.6 1.8 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 CCD25943.2 - 3.6e-05 23.7 1.1 0.00024 21.0 1.1 2.0 1 1 0 1 1 1 1 WH1 domain SR-25 PF10500.9 CCD25943.2 - 0.0043 16.7 4.1 0.0066 16.1 4.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Trehalase PF01204.18 CCD25944.2 - 1.2e-190 634.7 0.1 1.5e-190 634.4 0.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 CCD25944.2 - 5.3e-17 61.2 0.7 8.8e-17 60.5 0.7 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF1640 PF07798.11 CCD25945.2 - 1.1e-52 178.6 8.4 1.4e-52 178.3 8.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Spc7 PF08317.11 CCD25945.2 - 0.0029 16.5 4.6 0.0038 16.2 4.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein FTA4 PF13093.6 CCD25945.2 - 0.011 15.7 5.0 0.013 15.4 5.0 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF1732 PF08340.11 CCD25945.2 - 0.027 14.4 3.8 0.052 13.5 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) XhlA PF10779.9 CCD25945.2 - 0.062 13.5 3.5 0.35 11.1 0.1 2.6 2 0 0 2 2 2 0 Haemolysin XhlA FapA PF03961.13 CCD25945.2 - 0.075 11.6 10.4 0.093 11.3 10.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Phage_Mu_Gam PF07352.12 CCD25945.2 - 0.14 12.1 7.4 0.38 10.7 0.3 2.4 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF2730 PF10805.8 CCD25945.2 - 0.23 11.5 5.6 0.39 10.8 1.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) Sulfatase_C PF14707.6 CCD25945.2 - 0.25 12.1 1.4 9.4 7.0 0.0 2.6 1 1 1 3 3 3 0 C-terminal region of aryl-sulfatase DUF5082 PF16888.5 CCD25945.2 - 0.32 11.3 11.4 0.93 9.8 8.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) FlaC_arch PF05377.11 CCD25945.2 - 0.41 11.1 5.4 11 6.5 0.3 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Uso1_p115_C PF04871.13 CCD25945.2 - 0.48 10.8 7.6 0.7 10.3 4.9 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2524 PF10732.9 CCD25945.2 - 2.2 8.6 8.3 0.21 11.9 3.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) Phage_lysis PF03245.13 CCD25945.2 - 2.8 8.1 9.1 0.47 10.6 1.4 2.1 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein YlqD PF11068.8 CCD25945.2 - 4.5 7.6 12.8 16 5.9 9.4 2.3 1 1 1 2 2 2 0 YlqD protein PMM PF03332.13 CCD25946.2 - 1e-111 372.0 0.4 1.2e-111 371.8 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 CCD25946.2 - 0.00054 19.8 0.0 0.019 14.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CCD25946.2 - 0.054 13.0 0.0 0.27 10.7 0.0 1.8 1 1 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CCD25946.2 - 0.061 13.6 0.1 0.067 13.5 0.1 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase USP8_dimer PF08969.11 CCD25947.2 - 1.9e-06 28.0 0.1 3.5e-06 27.2 0.1 1.6 1 1 0 1 1 1 1 USP8 dimerisation domain VASt PF16016.5 CCD25948.2 - 9.6e-31 107.3 4.4 2.3e-30 106.0 4.4 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CCD25948.2 - 4.7e-23 81.3 0.6 2.1e-22 79.1 0.6 2.1 1 0 0 1 1 1 1 GRAM domain Cu-oxidase_2 PF07731.14 CCD25949.2 - 2.9e-44 150.1 9.7 5.1e-40 136.4 0.6 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CCD25949.2 - 5.9e-37 126.3 4.7 1.3e-33 115.5 1.7 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CCD25949.2 - 3.9e-32 111.6 4.6 3.9e-27 95.3 0.1 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 CCD25949.2 - 0.004 17.2 0.0 7.6 6.7 0.0 3.3 3 0 0 3 3 3 2 Cupredoxin-like domain SPC22 PF04573.12 CCD25950.2 - 1.7e-57 193.6 3.1 2.2e-57 193.3 3.1 1.1 1 0 0 1 1 1 1 Signal peptidase subunit Sugar_tr PF00083.24 CCD25951.2 - 2.6e-58 198.0 30.6 3e-58 197.8 30.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD25951.2 - 8e-24 84.2 32.9 5.6e-21 74.8 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SLATT_6 PF18169.1 CCD25951.2 - 0.25 10.9 0.0 0.25 10.9 0.0 2.6 4 0 0 4 4 4 0 SMODS and SLOG-associating 2TM effector domain 6 DUF1772 PF08592.11 CCD25951.2 - 5.2 7.4 8.9 1.2 9.5 0.9 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF1772) Pkinase PF00069.25 CCD25952.2 - 5.1e-53 180.1 3.2 2.6e-51 174.5 3.2 2.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD25952.2 - 3.7e-30 105.1 0.1 5.3e-29 101.3 0.1 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCD25952.2 - 0.031 13.0 0.0 0.071 11.9 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase SH3_1 PF00018.28 CCD25953.2 - 1.5e-09 37.3 0.0 3.8e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCD25953.2 - 0.0053 16.6 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain HEAT PF02985.22 CCD25954.2 - 2.9e-17 61.3 1.9 0.0019 18.3 0.0 7.9 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 CCD25954.2 - 1.3e-15 57.5 0.2 1.4e-11 44.6 0.0 5.5 7 0 0 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.6 CCD25954.2 - 2.2e-08 34.4 0.0 0.0012 19.1 0.0 4.7 3 2 1 4 4 4 3 HEAT repeats IBN_N PF03810.19 CCD25954.2 - 2e-05 24.4 1.4 0.00098 19.0 0.0 3.8 4 1 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.8 CCD25954.2 - 0.0014 18.3 0.0 0.4 10.2 0.0 3.5 3 0 0 3 3 3 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 CCD25954.2 - 0.0022 18.6 0.5 12 6.6 0.0 5.1 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CCD25954.2 - 0.034 14.2 12.1 0.11 12.6 0.1 5.0 4 2 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Spore_III_AB PF09548.10 CCD25954.2 - 0.15 12.2 0.2 0.71 10.0 0.1 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) ERK-JNK_inhib PF15002.6 CCD25954.2 - 0.24 11.1 1.6 16 5.1 0.1 3.1 2 1 1 3 3 3 0 ERK and JNK pathways, inhibitor Mannosyl_trans3 PF11051.8 CCD25955.2 - 4.4e-81 272.3 0.3 4.4e-81 272.3 0.3 1.8 2 0 0 2 2 2 1 Mannosyltransferase putative Rx_N PF18052.1 CCD25955.2 - 0.088 13.1 0.2 0.22 11.8 0.2 1.6 1 0 0 1 1 1 0 Rx N-terminal domain Glutaredoxin PF00462.24 CCD25956.2 - 1.5e-12 47.6 0.0 3.6e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.6 CCD25956.2 - 0.018 15.4 0.0 0.058 13.8 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SpoIISA_toxin PF14171.6 CCD25956.2 - 0.1 12.3 0.3 1.5 8.5 0.1 2.0 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system DUF3139 PF11337.8 CCD25956.2 - 0.11 13.2 0.2 0.25 12.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Hyphal_reg_CWP PF11765.8 CCD25957.2 - 5.5e-36 124.1 11.7 5.5e-36 124.1 11.7 1.8 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal CSG2 PF16965.5 CCD25958.2 - 5.1e-189 628.3 10.3 6.3e-189 628.0 10.3 1.1 1 0 0 1 1 1 1 Ceramide synthase regulator SCO1-SenC PF02630.14 CCD25959.2 - 1.5e-45 154.4 0.0 2.1e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 CCD25959.2 - 0.00022 21.1 0.0 0.00081 19.3 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CCD25959.2 - 0.12 12.1 0.0 0.47 10.2 0.0 1.9 1 1 0 1 1 1 0 Redoxin ABC2_membrane PF01061.24 CCD25960.2 - 2.5e-62 210.0 66.2 1.4e-38 132.5 20.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CCD25960.2 - 1.1e-38 132.8 0.0 7e-18 65.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CCD25960.2 - 3.6e-33 113.3 20.9 4.7e-32 109.8 0.0 3.8 4 0 0 4 4 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 CCD25960.2 - 1.1e-07 31.3 8.7 1.1e-07 31.3 8.7 3.9 3 2 0 3 3 3 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CCD25960.2 - 2.9e-07 30.6 0.0 0.00034 20.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CCD25960.2 - 3e-06 27.7 0.0 0.0033 17.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain ABC_trans_N PF14510.6 CCD25960.2 - 3.4e-06 27.6 0.3 7.8e-06 26.4 0.3 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 CCD25960.2 - 3.9e-05 23.6 0.0 0.071 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CCD25960.2 - 0.00014 22.2 0.4 0.0045 17.3 0.1 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CCD25960.2 - 0.00023 21.2 0.1 0.15 12.1 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 CCD25960.2 - 0.0015 18.2 0.1 0.065 13.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CCD25960.2 - 0.0019 18.7 0.1 0.026 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 CCD25960.2 - 0.0029 17.1 0.0 1.3 8.4 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 CCD25960.2 - 0.0054 16.3 0.6 0.014 15.0 0.1 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CCD25960.2 - 0.0096 16.1 0.0 0.027 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CCD25960.2 - 0.015 15.3 0.7 0.31 11.0 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 CCD25960.2 - 0.042 13.6 0.1 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CCD25960.2 - 0.047 13.4 0.5 0.42 10.3 0.0 2.8 4 0 0 4 4 3 0 AAA domain RNA_helicase PF00910.22 CCD25960.2 - 0.051 14.0 0.0 4.4 7.7 0.0 3.1 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 CCD25960.2 - 0.058 13.6 0.4 0.19 11.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CCD25960.2 - 0.078 13.5 0.2 0.41 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CCD25960.2 - 0.079 13.0 0.2 0.38 10.8 0.1 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 CCD25960.2 - 0.088 12.4 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain Septin PF00735.18 CCD25960.2 - 0.1 11.9 0.2 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.23 CCD25960.2 - 3 7.9 4.5 1.8 8.6 0.0 2.8 4 0 0 4 4 2 0 Dynamin family ABC2_membrane PF01061.24 CCD25961.2 - 3e-66 222.8 62.7 3.5e-41 140.9 16.8 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CCD25961.2 - 8e-39 133.3 0.0 7.5e-18 65.4 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 CCD25961.2 - 1.6e-36 124.1 7.8 5.3e-31 106.4 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 CCD25961.2 - 1.1e-07 32.3 0.1 2.7e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 CCD25961.2 - 4.2e-06 26.1 33.7 6.1e-06 25.6 6.5 3.3 2 2 1 3 3 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CCD25961.2 - 6.7e-06 26.1 0.1 0.00061 19.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 CCD25961.2 - 4.7e-05 23.4 0.0 0.033 14.0 0.0 2.6 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CCD25961.2 - 0.00012 22.5 0.2 0.0068 16.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CCD25961.2 - 0.0037 17.5 0.0 0.014 15.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CCD25961.2 - 0.0044 16.7 0.1 0.098 12.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CCD25961.2 - 0.0047 17.0 0.3 0.14 12.2 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 CCD25961.2 - 0.017 14.7 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CCD25961.2 - 0.024 15.2 0.0 0.085 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 CCD25961.2 - 0.051 13.0 0.0 1.9 7.8 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 CCD25961.2 - 0.056 13.8 0.0 2.9 8.3 0.0 3.1 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 CCD25961.2 - 0.073 12.8 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CCD25961.2 - 0.11 12.3 0.4 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CCD25961.2 - 0.14 11.8 0.1 0.39 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CCD25961.2 - 0.18 12.0 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CCD25961.2 - 0.32 10.9 0.8 0.59 10.0 0.1 1.8 2 0 0 2 2 2 0 NACHT domain GalP_UDP_tr_C PF02744.17 CCD25962.2 - 1.5e-67 226.5 0.4 3.1e-67 225.5 0.1 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 CCD25962.2 - 3.9e-67 226.2 0.4 5.5e-67 225.8 0.4 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF4921 PF16268.5 CCD25962.2 - 0.0038 16.1 0.3 1.5 7.5 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4921) WG_beta_rep PF14903.6 CCD25962.2 - 0.028 14.7 0.0 0.09 13.1 0.0 1.9 1 0 0 1 1 1 0 WG containing repeat HIT PF01230.23 CCD25962.2 - 0.13 13.0 0.0 0.47 11.2 0.0 1.9 2 0 0 2 2 2 0 HIT domain DUF3721 PF12518.8 CCD25962.2 - 9.1 6.2 6.4 0.9 9.4 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function ParA PF10609.9 CCD25963.2 - 7.5e-97 323.6 0.0 8.6e-97 323.4 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CCD25963.2 - 1.2e-09 38.3 0.0 8.9e-09 35.5 0.0 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CCD25963.2 - 5.4e-08 33.0 0.3 6.4e-07 29.5 0.3 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 CCD25963.2 - 2e-07 30.6 0.0 7e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CCD25963.2 - 1.3e-05 24.5 0.1 6.9e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 CCD25963.2 - 0.0012 18.4 0.0 0.13 11.7 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MeaB PF03308.16 CCD25963.2 - 0.0037 16.3 0.1 0.0059 15.6 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 CCD25963.2 - 0.028 13.9 0.0 0.12 11.9 0.0 1.8 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 CCD25963.2 - 0.036 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 CCD25963.2 - 0.064 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Gti1_Pac2 PF09729.9 CCD25964.2 - 2.5e-53 180.9 3.2 2.5e-53 180.9 3.2 4.5 2 1 0 2 2 2 1 Gti1/Pac2 family AAA PF00004.29 CCD25965.2 - 4e-38 130.8 0.0 1.3e-37 129.2 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCD25965.2 - 3.5e-09 36.3 0.1 7.3e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CCD25965.2 - 1.3e-08 34.7 2.1 2.8e-06 27.2 0.0 3.7 4 0 0 4 4 3 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 CCD25965.2 - 0.00019 21.7 1.6 0.0016 18.7 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CCD25965.2 - 0.00024 21.2 0.8 0.00083 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CCD25965.2 - 0.00029 20.6 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CCD25965.2 - 0.0025 18.4 0.1 0.024 15.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CCD25965.2 - 0.0025 17.8 0.1 0.017 15.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CCD25965.2 - 0.0049 16.3 0.7 0.017 14.5 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CCD25965.2 - 0.005 16.1 0.0 0.005 16.1 0.0 1.7 2 0 0 2 2 1 1 TIP49 P-loop domain AAA_16 PF13191.6 CCD25965.2 - 0.0059 17.0 0.0 0.032 14.6 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 CCD25965.2 - 0.0083 15.9 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 CCD25965.2 - 0.011 15.3 0.0 0.31 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CCD25965.2 - 0.012 15.7 0.0 0.16 12.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CCD25965.2 - 0.03 14.5 0.9 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Chromo PF00385.24 CCD25965.2 - 0.091 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain bZIP_1 PF00170.21 CCD25967.2 - 1.3e-07 31.6 11.9 2.8e-07 30.5 11.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CCD25967.2 - 2.2e-05 24.5 12.1 4.8e-05 23.3 12.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CCD25967.2 - 0.046 14.2 5.5 0.095 13.2 5.5 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Herpes_LAMP2 PF06126.11 CCD25967.2 - 0.07 11.7 0.1 0.098 11.3 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Intein_splicing PF14890.6 CCD25967.2 - 0.082 12.9 0.2 0.33 10.9 0.2 2.0 1 1 0 1 1 1 0 Intein splicing domain Csm1_N PF18504.1 CCD25967.2 - 0.22 11.9 0.2 0.22 11.9 0.2 2.2 3 0 0 3 3 3 0 Csm1 N-terminal domain Erg28 PF03694.13 CCD25969.2 - 4.1e-44 149.5 3.2 5.1e-44 149.2 3.2 1.1 1 0 0 1 1 1 1 Erg28 like protein SNF2_N PF00176.23 CCD25970.2 - 7.7e-68 228.8 0.6 1.4e-67 227.9 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCD25970.2 - 8.8e-22 77.6 0.0 3.2e-20 72.5 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD25970.2 - 4e-09 36.7 0.1 2.3e-08 34.2 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCD25970.2 - 1.3e-05 25.1 0.0 3.2e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWIRM PF04433.17 CCD25971.2 - 8.5e-28 96.5 0.3 8.5e-28 96.5 0.3 2.9 4 0 0 4 4 4 1 SWIRM domain ZZ PF00569.17 CCD25971.2 - 1e-11 44.4 3.5 1.6e-11 43.8 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 CCD25971.2 - 1.1e-08 35.1 0.0 2.8e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 CCD25971.2 - 1.6e-08 34.3 7.4 4e-08 33.1 7.4 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 CCD25971.2 - 3.2e-06 27.3 1.7 0.00014 22.0 0.1 3.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain zf-UBR PF02207.20 CCD25971.2 - 0.0048 17.0 0.9 0.0084 16.2 0.9 1.3 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Elf1 PF05129.13 CCD25971.2 - 0.076 13.1 0.9 0.18 11.9 0.9 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-CCHC_2 PF13696.6 CCD25971.2 - 0.11 12.4 6.6 3.3 7.6 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF4428 PF14471.6 CCD25971.2 - 0.9 9.5 2.5 4.5 7.3 1.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4428) Zn_ribbon_2 PF12674.7 CCD25971.2 - 9.3 7.0 6.0 1.8 9.3 0.1 2.9 3 1 1 4 4 4 0 Putative zinc ribbon domain STAG PF08514.11 CCD25972.2 - 2.4e-23 82.2 1.3 2.4e-23 82.2 1.3 2.7 2 0 0 2 2 2 1 STAG domain rve_3 PF13683.6 CCD25972.2 - 0.036 13.8 0.4 0.3 10.9 0.0 2.7 3 0 0 3 3 3 0 Integrase core domain Flu_NS2 PF00601.19 CCD25972.2 - 0.23 11.8 3.1 0.53 10.6 0.8 2.8 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) ANAPC_CDC26 PF10471.9 CCD25973.2 - 7.9e-08 33.0 0.9 1.1e-07 32.6 0.9 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 RNA_pol_A_bac PF01000.26 CCD25975.2 - 1.2e-33 115.8 0.5 4.3e-33 114.0 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CCD25975.2 - 3e-18 65.0 0.0 4e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF4602 PF15375.6 CCD25976.2 - 0.0039 17.5 1.9 0.0039 17.5 1.9 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4602) BSP_II PF05432.11 CCD25976.2 - 0.09 12.5 18.9 0.15 11.7 18.9 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) HLH PF00010.26 CCD25977.2 - 8.2e-10 38.5 1.5 2.6e-09 36.9 1.5 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UCR_hinge PF02320.16 CCD25978.2 - 6.5e-20 71.1 1.0 6.5e-20 71.1 1.0 1.6 2 0 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.13 CCD25978.2 - 0.00032 20.6 14.4 0.00037 20.4 14.4 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region Mpp10 PF04006.12 CCD25978.2 - 0.013 14.0 19.2 0.015 13.8 19.2 1.0 1 0 0 1 1 1 0 Mpp10 protein SGT1 PF07093.11 CCD25978.2 - 0.032 12.7 11.1 0.035 12.6 11.1 1.0 1 0 0 1 1 1 0 SGT1 protein DUF3381 PF11861.8 CCD25978.2 - 0.089 12.6 14.3 0.14 11.9 14.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF4481 PF14800.6 CCD25978.2 - 0.1 12.1 0.3 0.12 11.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) Spore_coat_CotO PF14153.6 CCD25978.2 - 0.14 12.0 9.3 0.16 11.9 9.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Nop14 PF04147.12 CCD25978.2 - 0.18 10.0 18.6 0.19 9.9 18.6 1.0 1 0 0 1 1 1 0 Nop14-like family D123 PF07065.14 CCD25978.2 - 0.23 10.6 8.0 0.32 10.1 8.0 1.2 1 0 0 1 1 1 0 D123 RPN2_C PF18004.1 CCD25978.2 - 0.24 11.3 8.9 0.29 11.0 8.9 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 CCD25978.2 - 0.3 9.3 13.3 0.31 9.3 13.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 CCD25978.2 - 0.55 8.3 26.3 0.62 8.1 26.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi DDRGK PF09756.9 CCD25978.2 - 0.6 9.7 19.5 0.81 9.3 19.5 1.2 1 0 0 1 1 1 0 DDRGK domain Tim54 PF11711.8 CCD25978.2 - 1 8.1 6.9 1.1 8.0 6.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TRAP_alpha PF03896.16 CCD25978.2 - 1.1 8.4 11.5 1.3 8.2 11.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 CCD25978.2 - 1.4 7.6 3.8 1.5 7.5 3.8 1.0 1 0 0 1 1 1 0 Presenilin CobT PF06213.12 CCD25978.2 - 1.6 8.1 17.8 1.7 7.9 17.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 CCD25978.2 - 1.6 8.0 16.8 1.8 7.8 16.8 1.0 1 0 0 1 1 1 0 BUD22 PDDEXK_6 PF04720.12 CCD25978.2 - 1.8 8.5 7.0 2.2 8.2 7.0 1.1 1 0 0 1 1 1 0 PDDEXK-like family of unknown function DUF4637 PF15470.6 CCD25978.2 - 1.9 8.2 16.2 2.5 7.8 16.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2428 PF10350.9 CCD25978.2 - 2.2 7.5 4.0 2.6 7.2 4.0 1.2 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) V_ATPase_I PF01496.19 CCD25978.2 - 3.2 5.6 5.0 3.2 5.5 5.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RRN3 PF05327.11 CCD25978.2 - 4.2 5.8 14.2 4.1 5.8 14.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.11 CCD25978.2 - 4.7 5.2 7.8 5.2 5.0 7.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.12 CCD25978.2 - 4.9 6.5 20.5 5.6 6.3 20.5 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 CCD25978.2 - 7.1 6.3 21.9 8.4 6.0 21.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pes-10 PF07149.11 CCD25978.2 - 8.5 5.3 16.9 9.8 5.1 16.9 1.3 1 0 0 1 1 1 0 Pes-10 DUF2457 PF10446.9 CCD25978.2 - 9.6 5.2 23.6 11 5.1 23.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ribosomal_L29e PF01779.17 CCD25979.2 - 8e-24 83.7 9.4 1.1e-23 83.3 9.4 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family RRM_1 PF00076.22 CCD25980.2 - 3.9e-16 58.6 0.1 2.1e-08 33.9 0.0 3.2 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L2_C PF03947.18 CCD25981.2 - 1.3e-44 151.4 3.5 2.2e-44 150.7 3.5 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CCD25981.2 - 2.1e-13 50.0 0.2 5.7e-13 48.6 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SMC_N PF02463.19 CCD25982.2 - 2.7e-66 223.2 25.1 1.8e-64 217.2 25.1 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CCD25982.2 - 2.7e-19 69.6 0.0 8.5e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 CCD25982.2 - 1.1e-07 32.0 24.6 1.1e-07 32.0 24.6 4.4 2 2 2 4 4 4 1 AAA ATPase domain AAA_21 PF13304.6 CCD25982.2 - 3e-06 27.3 23.9 7.8e-05 22.6 0.7 4.4 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCD25982.2 - 2.7e-05 23.8 0.0 0.00015 21.5 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF16 PF01519.16 CCD25982.2 - 0.008 16.6 8.5 0.008 16.6 8.5 7.6 2 2 3 6 6 6 1 Protein of unknown function DUF16 DUF3866 PF12982.7 CCD25982.2 - 0.028 13.6 0.2 6.2 5.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3866) ABC_tran PF00005.27 CCD25982.2 - 0.075 13.5 0.1 0.075 13.5 0.1 5.9 3 3 0 4 4 4 0 ABC transporter AAA_23 PF13476.6 CCD25982.2 - 0.11 12.9 126.5 0.048 14.2 53.5 7.3 2 2 2 4 4 4 0 AAA domain FAD_binding_1 PF00667.20 CCD25983.2 - 8.8e-64 215.1 0.0 1.6e-63 214.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CCD25983.2 - 2.2e-07 31.5 0.8 4.2e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Imm52 PF15579.6 CCD25983.2 - 0.052 13.4 0.1 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 Immunity protein 52 Tim54 PF11711.8 CCD25983.2 - 0.2 10.4 5.5 0.33 9.7 5.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CENP-B_dimeris PF09026.10 CCD25983.2 - 0.24 11.8 2.8 0.74 10.2 2.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PDZ_1 PF12812.7 CCD25983.2 - 0.71 9.9 2.8 17 5.5 0.1 2.9 2 0 0 2 2 2 0 PDZ-like domain EST1_DNA_bind PF10373.9 CCD25985.2 - 4.1e-33 115.1 1.5 1.3e-32 113.5 1.5 1.9 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 CCD25985.2 - 8.7e-12 45.8 0.4 8.7e-12 45.8 0.4 2.0 2 1 0 2 2 2 1 Telomerase activating protein Est1 Topoisom_bac PF01131.20 CCD25986.2 - 5.9e-100 335.2 0.0 9.2e-100 334.5 0.0 1.3 1 1 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CCD25986.2 - 4.6e-21 75.0 0.0 1.3e-20 73.5 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Transp_cyt_pur PF02133.15 CCD25987.2 - 3e-71 240.5 38.8 3.8e-71 240.2 38.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Rogdi_lz PF10259.9 CCD25988.2 - 1.7e-66 224.4 8.0 2e-66 224.2 8.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein FHA PF00498.26 CCD25989.2 - 1e-17 64.2 0.6 7.6e-17 61.4 0.2 2.7 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CCD25989.2 - 2e-06 28.0 0.0 1e-05 25.8 0.0 2.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain IKKbetaNEMObind PF12179.8 CCD25989.2 - 0.23 11.5 1.5 1.1 9.3 1.5 2.2 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain EMC3_TMCO1 PF01956.16 CCD25989.2 - 8.7 6.0 12.2 11 5.8 1.2 3.2 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like BPL_LplA_LipB PF03099.19 CCD25990.2 - 1.3e-17 64.0 0.1 2.2e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PI3Ka PF00613.20 CCD25991.2 - 1.6e-74 249.4 2.6 2.6e-74 248.6 2.6 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 CCD25991.2 - 2e-51 175.3 0.0 1.8e-32 113.2 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 CCD25991.2 - 4.2e-23 81.8 2.1 4.6e-23 81.7 0.4 2.0 3 0 0 3 3 3 1 Phosphoinositide 3-kinase C2 RSN1_7TM PF02714.15 CCD25992.2 - 2.1e-81 273.2 24.3 2.1e-81 273.2 24.3 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CCD25992.2 - 1.4e-39 135.4 4.5 1.4e-39 135.4 4.5 2.3 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CCD25992.2 - 1.8e-33 116.2 0.0 2.8e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Arv1 PF04161.13 CCD25993.2 - 2.3e-66 224.0 9.5 2.3e-66 224.0 9.5 1.4 2 0 0 2 2 2 1 Arv1-like family DZR PF12773.7 CCD25993.2 - 0.098 12.7 0.3 0.18 11.8 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon ATP_bind_1 PF03029.17 CCD25994.2 - 1.7e-88 296.5 0.0 1.9e-88 296.3 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 CCD25994.2 - 0.0015 18.4 0.0 0.0064 16.3 0.0 2.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 CCD25994.2 - 0.0017 17.4 0.1 0.0028 16.7 0.0 1.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 CCD25994.2 - 0.0028 17.6 0.2 0.068 13.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_10 PF12846.7 CCD25994.2 - 0.0043 16.0 0.0 0.0069 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.23 CCD25994.2 - 0.0076 16.3 0.0 0.021 14.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCD25994.2 - 0.01 15.4 0.0 0.26 10.8 0.0 2.4 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain RNA_helicase PF00910.22 CCD25994.2 - 0.011 16.1 0.0 0.033 14.6 0.0 1.8 2 0 0 2 2 1 0 RNA helicase ABC_tran PF00005.27 CCD25994.2 - 0.012 16.2 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF87 PF01935.17 CCD25994.2 - 0.012 15.7 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 CCD25994.2 - 0.012 16.1 0.0 0.029 14.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CCD25994.2 - 0.016 14.7 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 CCD25994.2 - 0.024 13.9 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain T2SSE PF00437.20 CCD25994.2 - 0.024 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 CCD25994.2 - 0.032 14.0 0.0 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 CCD25994.2 - 0.037 13.7 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CCD25994.2 - 0.05 13.4 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CCD25994.2 - 0.055 13.8 0.0 0.13 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CCD25994.2 - 0.061 12.5 0.8 0.17 11.0 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 CCD25994.2 - 0.062 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CCD25994.2 - 0.069 13.5 0.1 0.19 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CCD25994.2 - 0.08 13.3 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CCD25994.2 - 0.1 13.0 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CCD25994.2 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 CCD25994.2 - 0.12 11.9 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.26 CCD25994.2 - 0.15 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 CCD25994.2 - 0.16 11.9 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AIG1 PF04548.16 CCD25994.2 - 0.18 11.1 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 AIG1 family TIP49 PF06068.13 CCD25995.2 - 8.8e-169 561.2 0.6 1.1e-168 560.9 0.6 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CCD25995.2 - 1.2e-22 79.8 0.2 3e-22 78.5 0.2 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CCD25995.2 - 4.2e-08 33.7 0.9 8.6e-05 23.0 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CCD25995.2 - 1.4e-07 31.4 0.1 5.2e-05 23.1 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CCD25995.2 - 0.0012 19.1 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCD25995.2 - 0.0047 17.3 0.6 3.7 7.9 0.2 2.4 2 0 0 2 2 2 2 AAA domain DnaB_C PF03796.15 CCD25995.2 - 0.013 14.8 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_5 PF07728.14 CCD25995.2 - 0.017 15.1 0.2 0.7 9.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCD25995.2 - 0.02 15.3 0.3 0.15 12.5 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 CCD25995.2 - 0.03 13.7 0.1 3.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 CCD25995.2 - 0.042 13.7 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.6 CCD25995.2 - 0.052 13.6 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CCD25995.2 - 0.054 13.2 0.3 6.2 6.5 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CCD25995.2 - 0.078 12.3 0.1 0.18 11.1 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin Sec1 PF00995.23 CCD25996.2 - 2.2e-119 400.3 10.5 2.5e-119 400.1 10.5 1.0 1 0 0 1 1 1 1 Sec1 family Cpn60_TCP1 PF00118.24 CCD25997.2 - 6.4e-158 526.4 2.3 7.2e-158 526.2 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M24 PF00557.24 CCD25998.2 - 2.9e-48 164.3 0.1 3.7e-48 164.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 CCD25998.2 - 6.6e-17 61.6 6.0 6.6e-17 61.6 6.0 1.7 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding dCMP_cyt_deam_1 PF00383.23 CCD25999.2 - 7.6e-10 38.6 2.3 4.6e-09 36.1 2.3 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CCD25999.2 - 6.6e-06 25.9 1.1 0.0006 19.5 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_2 PF08211.12 CCD25999.2 - 2e-05 24.8 0.6 0.01 16.0 0.0 2.6 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Motilin_assoc PF04643.12 CCD25999.2 - 0.19 11.6 0.0 3.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Motilin/ghrelin-associated peptide DHHC PF01529.20 CCD26000.2 - 7.8e-32 110.2 10.7 7.8e-32 110.2 10.7 2.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF2645 PF10840.8 CCD26000.2 - 0.031 14.9 2.4 0.031 14.9 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2645) ATP-synt_I PF03899.15 CCD26000.2 - 0.087 13.2 0.2 0.087 13.2 0.2 2.3 2 0 0 2 2 2 0 ATP synthase I chain RDD PF06271.12 CCD26000.2 - 0.93 9.7 7.0 7 6.8 0.2 2.4 2 0 0 2 2 2 0 RDD family PRELI PF04707.14 CCD26001.2 - 9.6e-54 181.5 0.2 1.6e-53 180.7 0.2 1.3 1 0 0 1 1 1 1 PRELI-like family DUP PF00674.18 CCD26002.2 - 7.1e-19 67.9 0.2 1.6e-18 66.7 0.2 1.6 1 0 0 1 1 1 1 DUP family COX15-CtaA PF02628.15 CCD26002.2 - 0.01 14.9 0.2 0.014 14.5 0.2 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein DUF1385 PF07136.11 CCD26002.2 - 0.076 12.3 1.2 0.1 11.9 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) DUF4051 PF13260.6 CCD26002.2 - 1.7 8.5 4.9 1.2 8.9 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) ubiquitin PF00240.23 CCD26003.2 - 3.8e-34 116.3 0.6 7.7e-34 115.3 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 CCD26003.2 - 5.8e-24 84.0 3.0 5.8e-24 84.0 3.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 CCD26003.2 - 4.7e-16 58.4 0.7 4.7e-16 58.4 0.7 1.7 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CCD26003.2 - 2.3e-05 24.7 0.1 0.00012 22.4 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CCD26003.2 - 0.0013 18.9 0.6 0.0029 17.7 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CCD26003.2 - 0.0037 17.6 0.5 0.0077 16.6 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CCD26003.2 - 0.0051 16.7 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 CCD26003.2 - 0.014 15.9 0.6 0.019 15.5 0.6 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CCD26003.2 - 0.019 15.0 1.0 5.7 7.1 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 CCD26003.2 - 0.02 15.1 0.3 0.034 14.4 0.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Sec10 PF07393.11 CCD26004.2 - 5.8e-194 646.5 32.7 8e-194 646.0 32.7 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 COG2 PF06148.11 CCD26004.2 - 4.1 7.5 11.4 0.24 11.5 1.2 3.8 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 PseudoU_synth_2 PF00849.22 CCD26005.2 - 2.5e-18 66.7 0.0 1.8e-17 63.9 0.0 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase DUP PF00674.18 CCD26006.2 - 2.3e-22 79.0 2.8 4.8e-22 78.0 2.8 1.5 1 0 0 1 1 1 1 DUP family Peptidase_M16 PF00675.20 CCD26007.2 - 2.6e-52 176.8 0.0 4.8e-52 175.9 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CCD26007.2 - 2.2e-34 119.0 0.0 5.8e-33 114.5 0.0 2.3 3 0 0 3 3 3 1 Peptidase M16 inactive domain BHD_1 PF10403.9 CCD26008.2 - 1.8e-14 53.3 0.0 4.9e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.9 CCD26008.2 - 3.7e-13 49.7 0.2 9.4e-13 48.4 0.2 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 CCD26008.2 - 4.9e-08 32.8 0.3 1.3e-07 31.4 0.3 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 CCD26008.2 - 0.002 19.0 0.3 0.0056 17.6 0.3 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 tRNA_bind_2 PF13725.6 CCD26009.2 - 0.029 14.1 1.0 0.055 13.2 1.0 1.4 1 0 0 1 1 1 0 Possible tRNA binding domain TMEM51 PF15345.6 CCD26009.2 - 0.38 10.6 0.1 0.38 10.6 0.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 AMP-binding PF00501.28 CCD26010.2 - 5.1e-81 272.4 0.0 6.2e-81 272.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCD26010.2 - 1.6e-21 77.0 0.0 3.2e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CCD26010.2 - 2.9e-19 68.7 0.2 6.2e-19 67.7 0.2 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus NUDIX PF00293.28 CCD26011.2 - 4.4e-14 52.7 0.0 7.7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain RNA_pol_N PF01194.17 CCD26011.2 - 0.12 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit Stb3 PF10330.9 CCD26012.2 - 4.5e-31 106.7 0.3 2.2e-30 104.5 0.0 2.1 2 0 0 2 2 2 1 Putative Sin3 binding protein DUF2415 PF10313.9 CCD26013.2 - 1.4e-21 76.2 0.8 3.4e-21 74.9 0.8 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Pep3_Vps18 PF05131.14 CCD26014.2 - 7.2e-40 136.2 0.2 7.2e-40 136.2 0.2 3.0 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CCD26014.2 - 9e-07 28.9 31.4 5.7e-06 26.3 5.7 4.1 4 0 0 4 4 4 2 Region in Clathrin and VPS Vps39_2 PF10367.9 CCD26014.2 - 0.0001 22.7 1.5 0.0001 22.7 1.5 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 CCD26014.2 - 0.00091 19.1 4.9 0.0017 18.3 4.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CCD26014.2 - 0.0058 16.2 1.5 0.011 15.3 1.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 CCD26014.2 - 0.0095 16.8 0.3 2.7 9.0 0.0 3.5 1 1 1 2 2 2 1 WD domain, G-beta repeat zf-RING_2 PF13639.6 CCD26014.2 - 0.042 14.2 5.6 0.085 13.2 5.6 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 CCD26014.2 - 0.15 12.1 3.3 0.34 11.0 3.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CCD26014.2 - 0.19 11.6 5.3 0.38 10.6 5.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CCD26014.2 - 0.32 10.8 7.4 0.73 9.6 7.4 1.6 1 0 0 1 1 1 0 RING-like zinc finger LSM PF01423.22 CCD26015.2 - 2.5e-14 52.7 0.3 2.7e-14 52.6 0.3 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 CCD26015.2 - 0.01 15.9 0.1 0.01 15.9 0.1 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain SM-ATX PF14438.6 CCD26015.2 - 0.081 13.1 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Spermine_synth PF01564.17 CCD26017.2 - 1.3e-67 226.9 0.2 1.8e-67 226.4 0.2 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CCD26017.2 - 1.2e-22 79.6 0.0 2.1e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_31 PF13847.6 CCD26017.2 - 0.00067 19.5 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCD26017.2 - 0.0065 17.1 0.1 0.15 12.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCD26017.2 - 0.051 14.3 0.0 0.13 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF4477 PF14780.6 CCD26018.2 - 0.032 13.9 4.8 0.48 10.0 4.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4477) Glyco_hydro81C PF17652.1 CCD26019.2 - 5.7e-151 502.7 5.2 7.5e-151 502.3 5.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CCD26019.2 - 8.6e-94 314.3 3.3 1.3e-93 313.7 3.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Diphthami_syn_2 PF01902.17 CCD26021.2 - 1.6e-35 122.6 0.0 4.7e-35 121.1 0.0 1.8 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 CCD26021.2 - 9.7e-16 57.9 0.0 9.4e-07 28.9 0.0 2.6 2 0 0 2 2 2 2 Endoribonuclease L-PSP Nore1-SARAH PF16517.5 CCD26023.1 - 0.033 14.1 5.9 0.35 10.8 0.6 3.2 3 0 0 3 3 3 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain SLS PF14611.6 CCD26024.2 - 6.9e-36 124.1 12.5 6.9e-36 124.1 12.5 2.5 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator POX PF07526.11 CCD26024.2 - 5.9 7.5 7.1 1.6 9.3 1.2 2.6 3 0 0 3 3 3 0 Associated with HOX Hyphal_reg_CWP PF11765.8 CCD26025.2 - 3.2e-27 95.3 14.1 6.2e-27 94.4 14.1 1.4 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Na_H_Exchanger PF00999.21 CCD26026.2 - 5.3e-93 311.8 25.3 6.4e-93 311.6 25.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.10 CCD26026.2 - 1.8e-51 175.8 45.5 2.6e-51 175.3 44.7 1.6 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Inhibitor_I48 PF10467.9 CCD26027.1 - 0.19 11.6 0.0 0.57 10.0 0.0 1.7 2 0 0 2 2 2 0 Peptidase inhibitor clitocypin Methyltransf_16 PF10294.9 CCD26028.2 - 2.1e-06 27.6 3.7 0.00037 20.3 1.6 2.9 2 1 0 2 2 2 2 Lysine methyltransferase Rav1p_C PF12234.8 CCD26028.2 - 0.0014 17.1 0.2 0.0014 17.1 0.2 1.4 2 0 0 2 2 2 1 RAVE protein 1 C terminal DPM2 PF07297.12 CCD26028.2 - 0.25 11.7 1.4 0.69 10.3 0.4 2.0 2 0 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Eapp_C PF10238.9 CCD26028.2 - 0.44 10.6 3.6 6 6.9 1.3 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Afi1 PF07792.12 CCD26028.2 - 1.1 9.7 9.6 0.61 10.6 1.2 2.5 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2956 PF11169.8 CCD26028.2 - 1.6 9.0 10.0 9.2 6.5 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) zf-CCCH PF00642.24 CCD26029.2 - 4.2e-15 55.2 14.3 1.3e-07 31.3 0.8 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CCD26029.2 - 2.8e-05 24.0 17.2 0.012 15.6 8.4 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CCD26029.2 - 0.016 15.0 13.5 0.13 12.1 0.4 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger Torus PF16131.5 CCD26029.2 - 0.03 15.0 2.7 0.03 15.0 2.7 2.8 1 1 1 2 2 2 0 Torus domain oligo_HPY PF08352.12 CCD26029.2 - 0.54 10.8 3.6 6 7.5 0.1 2.6 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region Pheromone PF08015.11 CCD26029.2 - 2.8 9.1 9.1 3.2 8.9 1.5 2.6 2 0 0 2 2 2 0 Fungal mating-type pheromone zf-CCCH_2 PF14608.6 CCD26029.2 - 4.6 7.9 12.3 14 6.4 5.5 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Slx4 PF09494.10 CCD26030.2 - 4e-15 55.5 0.6 8.5e-15 54.5 0.6 1.6 1 0 0 1 1 1 1 Slx4 endonuclease Choline_kinase PF01633.20 CCD26031.2 - 3.6e-67 226.1 0.1 5.8e-67 225.4 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 CCD26031.2 - 6e-14 51.5 0.0 1.4e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 CCD26031.2 - 0.00019 21.5 0.0 0.017 15.0 0.0 2.4 2 1 0 2 2 2 2 Phosphotransferase enzyme family Mucin PF01456.17 CCD26031.2 - 0.069 13.1 26.7 0.29 11.1 0.4 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein HVSL PF09749.9 CCD26032.2 - 2.4e-34 118.9 2.8 2.8e-34 118.7 2.8 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein TetR_C_17 PF17922.1 CCD26032.2 - 0.054 13.6 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf-C2H2 PF00096.26 CCD26033.2 - 1.8e-07 31.3 9.1 0.005 17.2 2.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD26033.2 - 0.0027 18.4 6.2 0.99 10.4 1.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-TRAF PF02176.18 CCD26033.2 - 0.026 15.2 1.4 0.053 14.2 1.4 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger zf-H2C2_2 PF13465.6 CCD26033.2 - 0.042 14.3 0.3 0.042 14.3 0.3 3.4 3 1 0 3 3 3 0 Zinc-finger double domain zf_ZIC PF18366.1 CCD26033.2 - 0.28 11.3 1.7 12 6.1 0.2 2.6 2 0 0 2 2 2 0 Zic proteins zinc finger domain FAF PF11250.8 CCD26033.2 - 0.35 11.2 0.0 0.35 11.2 0.0 2.6 2 0 0 2 2 2 0 Fantastic Four meristem regulator zf-C2H2_jaz PF12171.8 CCD26033.2 - 0.37 11.1 9.2 1.9 8.8 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HisK_sensor PF18698.1 CCD26033.2 - 9.1 6.7 14.0 0.74 10.2 4.0 3.4 2 1 1 3 3 3 0 Histidine kinase sensor domain Zip PF02535.22 CCD26034.2 - 3.1e-87 292.9 0.0 5.2e-87 292.2 0.0 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.13 CCD26034.2 - 0.0018 17.8 2.2 0.0018 17.8 2.2 2.3 2 1 1 3 3 3 1 UNC-50 family Herpes_LMP1 PF05297.11 CCD26034.2 - 0.22 10.7 8.6 0.38 9.9 8.6 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Presenilin PF01080.17 CCD26034.2 - 0.62 8.8 5.3 0.038 12.8 0.3 1.5 2 0 0 2 2 2 0 Presenilin RRN3 PF05327.11 CCD26034.2 - 1.6 7.2 8.1 2.2 6.7 8.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BSP_II PF05432.11 CCD26034.2 - 2.1 8.0 15.3 3 7.5 15.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) WD40 PF00400.32 CCD26035.2 - 1.5e-48 161.7 32.1 6.6e-07 29.9 0.3 11.4 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.12 CCD26035.2 - 1.5e-21 76.7 0.2 3.1e-21 75.7 0.2 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 CCD26035.2 - 1e-16 61.0 8.1 0.00024 21.3 0.0 8.6 3 3 5 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCD26035.2 - 1.6e-06 27.1 3.3 0.02 13.6 0.0 5.3 4 2 0 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CCD26035.2 - 1.9e-06 27.5 18.1 4e-05 23.1 0.4 5.8 4 3 3 7 7 7 3 WD40-like domain Hira PF07569.11 CCD26035.2 - 0.0071 16.1 0.7 0.75 9.5 0.0 3.7 4 0 0 4 4 4 1 TUP1-like enhancer of split ELYS-bb PF16687.5 CCD26035.2 - 0.018 13.7 0.0 0.46 9.0 0.0 2.6 3 0 0 3 3 3 0 beta-propeller of ELYS nucleoporin eIF2A PF08662.11 CCD26035.2 - 0.24 11.2 3.9 0.67 9.8 0.0 3.8 5 2 1 6 6 6 0 Eukaryotic translation initiation factor eIF2A Cullin_binding PF03556.15 CCD26036.2 - 8.4e-28 97.2 8.8 1.1e-23 83.9 5.9 2.5 2 0 0 2 2 2 2 Cullin binding UBA_4 PF14555.6 CCD26036.2 - 4.9e-06 26.3 0.5 4.7e-05 23.1 0.1 2.5 2 0 0 2 2 2 1 UBA-like domain HARP PF07443.13 CCD26036.2 - 0.035 13.7 0.1 0.11 12.1 0.1 1.9 1 0 0 1 1 1 0 HepA-related protein (HARP) ANAPC2 PF08672.11 CCD26037.2 - 2.3e-20 72.8 2.8 1.2e-19 70.5 0.2 3.5 3 0 0 3 3 3 1 Anaphase promoting complex (APC) subunit 2 FANCI_S1 PF14675.6 CCD26037.2 - 0.021 14.4 0.6 0.045 13.3 0.1 1.8 2 0 0 2 2 2 0 FANCI solenoid 1 GATase PF00117.28 CCD26038.2 - 1.3e-11 44.7 0.0 2.4e-11 43.7 0.0 1.5 1 1 1 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CCD26038.2 - 0.028 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase C26 Asp PF00026.23 CCD26039.2 - 3.7e-72 243.4 13.7 3.7e-72 243.4 13.7 2.1 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCD26039.2 - 5.5e-11 43.0 6.2 5.5e-11 43.0 6.2 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal GcnA_N PF18229.1 CCD26039.2 - 0.049 13.7 0.1 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 N-acetyl-beta-D-glucosaminidase N-terminal domain Asp_protease_2 PF13650.6 CCD26039.2 - 0.092 13.4 1.1 13 6.6 0.4 3.5 2 1 0 2 2 2 0 Aspartyl protease Lin-8 PF03353.15 CCD26039.2 - 2.4 7.6 3.6 3.7 7.0 3.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF572 PF04502.13 CCD26039.2 - 2.9 7.4 8.5 4.3 6.9 8.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-RING_2 PF13639.6 CCD26040.2 - 1.9e-09 37.7 4.8 6.5e-08 32.8 0.9 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 CCD26040.2 - 1.5e-06 28.4 1.4 3.5e-06 27.2 0.3 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CCD26040.2 - 3.3e-06 26.9 2.0 7.9e-06 25.6 2.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CCD26040.2 - 5.1e-05 23.2 5.2 0.00051 20.0 0.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CCD26040.2 - 7.3e-05 22.8 1.8 7.3e-05 22.8 1.8 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CCD26040.2 - 7.7e-05 22.5 1.0 7.7e-05 22.5 1.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CCD26040.2 - 0.00018 21.3 3.6 0.00024 20.9 1.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCD26040.2 - 0.00047 20.1 2.2 0.01 15.8 0.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CCD26040.2 - 0.0015 18.4 3.7 0.0028 17.5 0.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 CCD26040.2 - 0.022 14.9 0.4 0.045 13.9 0.4 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 CCD26040.2 - 0.034 14.2 0.5 0.071 13.2 0.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CCD26040.2 - 0.19 11.5 2.5 7.7 6.4 0.2 2.4 2 0 0 2 2 2 0 RING-like zinc finger Mod_r PF07200.13 CCD26041.2 - 3.2e-19 69.5 12.7 5.5e-19 68.7 12.7 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein RPW8 PF05659.11 CCD26041.2 - 0.013 15.2 0.3 0.025 14.2 0.3 1.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Tma16 PF11176.8 CCD26041.2 - 0.12 12.2 5.2 0.091 12.6 1.8 2.3 1 1 1 2 2 2 0 Translation machinery-associated protein 16 DivIC PF04977.15 CCD26041.2 - 0.39 10.5 4.2 0.097 12.4 0.7 1.8 2 0 0 2 2 2 0 Septum formation initiator YabA PF06156.13 CCD26041.2 - 2 9.1 8.3 0.31 11.7 1.6 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Abhydrolase_2 PF02230.16 CCD26042.2 - 1.1e-54 185.5 0.0 1.2e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CCD26042.2 - 6.1e-08 32.6 0.0 1.1e-07 31.7 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 CCD26042.2 - 0.00011 21.6 0.0 2.4 7.4 0.0 3.1 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCD26042.2 - 0.00019 22.1 0.0 0.00021 22.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CCD26042.2 - 0.00037 20.2 0.1 0.0012 18.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 CCD26042.2 - 0.0057 16.2 0.0 0.0082 15.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family TPR_14 PF13428.6 CCD26043.2 - 5.5e-16 57.9 0.6 0.016 16.0 0.0 8.6 8 2 3 11 11 10 3 Tetratricopeptide repeat HAT PF02184.16 CCD26043.2 - 2e-09 37.2 31.9 0.00027 20.8 0.5 8.2 10 0 0 10 10 10 4 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 CCD26043.2 - 2.8e-08 34.2 0.0 0.39 11.2 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CCD26043.2 - 2.9e-06 27.0 10.4 0.53 10.5 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 CCD26043.2 - 0.0047 16.7 5.7 7.7 6.5 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CCD26043.2 - 0.034 14.5 4.3 1.1 9.8 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCD26043.2 - 0.04 14.0 7.0 7.8 6.8 0.3 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCD26043.2 - 0.045 14.4 0.1 20 5.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat NRDE-2 PF08424.10 CCD26043.2 - 0.069 12.3 0.1 0.069 12.3 0.1 6.7 2 2 5 7 7 7 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 CCD26043.2 - 0.078 13.6 2.2 46 5.0 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CCD26043.2 - 0.12 12.7 12.6 4.8 7.7 0.6 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 CCD26043.2 - 0.21 11.7 21.5 0.047 13.8 1.4 5.7 5 2 1 6 6 6 0 U3 small nucleolar RNA-associated protein 6 DIOX_N PF14226.6 CCD26043.2 - 0.27 12.0 2.7 0.31 11.8 0.4 2.3 1 1 1 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal Arc_PepC_II PF06847.11 CCD26043.2 - 2.2 8.9 4.7 7.9 7.1 0.1 3.7 3 1 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II SF1-HH PF16275.5 CCD26044.2 - 2e-40 137.7 0.7 4.4e-40 136.5 0.7 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 CCD26044.2 - 8.3e-08 32.0 0.1 3.1e-07 30.1 0.1 1.9 2 0 0 2 2 2 1 KH domain zf-CCHC PF00098.23 CCD26044.2 - 2e-05 24.4 9.8 0.00015 21.7 1.0 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 CCD26044.2 - 0.0048 16.8 8.2 0.062 13.3 2.2 2.7 1 1 1 2 2 2 2 Zinc knuckle Lar_restr_allev PF14354.6 CCD26044.2 - 0.074 13.4 4.9 0.14 12.5 4.9 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar PHD_4 PF16866.5 CCD26044.2 - 0.23 11.6 2.1 0.54 10.4 2.1 1.6 1 0 0 1 1 1 0 PHD-finger zf-CCHC_4 PF14392.6 CCD26044.2 - 0.27 11.0 5.6 3.3 7.5 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 CCD26044.2 - 0.63 9.9 8.4 2.2 8.2 2.1 3.0 1 1 1 2 2 2 0 Zinc knuckle Lactamase_B_6 PF16661.5 CCD26045.2 - 7.6e-75 250.6 0.1 1.5e-74 249.6 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CCD26045.2 - 8e-24 84.7 10.4 2.1e-23 83.4 0.4 3.9 3 1 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Avl9 PF09794.9 CCD26046.2 - 1.7e-147 491.0 3.5 2.9e-147 490.3 3.5 1.4 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 CCD26046.2 - 4.7e-08 33.0 1.9 0.0005 20.0 0.0 3.1 2 1 1 3 3 3 2 Stabilization of polarity axis DUF2347 PF09804.9 CCD26046.2 - 2.4e-07 30.6 1.3 2.4e-07 30.6 1.3 4.8 3 2 1 4 4 4 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 CCD26046.2 - 9.2e-06 25.7 1.4 7.8e-05 22.7 1.4 2.3 1 1 0 1 1 1 1 DENN (AEX-3) domain Afi1 PF07792.12 CCD26046.2 - 0.09 13.3 0.1 0.09 13.3 0.1 6.3 2 2 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Pkinase PF00069.25 CCD26047.2 - 8.2e-67 225.3 0.0 1.3e-66 224.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26047.2 - 7.6e-31 107.3 0.0 1.3e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCD26047.2 - 3.3e-06 26.3 0.1 3.3e-06 26.3 0.1 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CCD26047.2 - 0.00016 21.1 0.1 0.00061 19.2 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCD26047.2 - 0.0003 20.8 0.3 0.0025 17.8 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Ribosomal_60s PF00428.19 CCD26047.2 - 0.011 16.3 1.7 0.024 15.2 0.7 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Kinase-like PF14531.6 CCD26047.2 - 0.014 14.7 0.0 0.37 10.1 0.0 2.3 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 CCD26047.2 - 0.026 14.2 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CCD26047.2 - 0.044 12.6 1.9 0.77 8.5 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 CCD26047.2 - 0.051 13.2 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 RIO1 family YbgS PF13985.6 CCD26047.2 - 6.7 7.0 15.0 11 6.3 15.0 1.3 1 0 0 1 1 1 0 YbgS-like protein Flocculin_t3 PF13928.6 CCD26049.2 - 6e-15 55.5 16.9 6e-15 55.5 16.9 2.2 1 1 1 2 2 2 1 Flocculin type 3 repeat MSP1_C PF07462.11 CCD26049.2 - 1.5 7.4 6.4 1.6 7.3 6.4 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Redoxin PF08534.10 CCD26050.2 - 8.9e-31 106.6 0.7 9.8e-31 106.5 0.7 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CCD26050.2 - 7.7e-06 25.8 0.1 1.1e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA family BTB_2 PF02214.22 CCD26051.2 - 6.4e-08 32.9 5.1 0.00081 19.7 0.6 3.3 3 1 0 3 3 3 2 BTB/POZ domain SR-25 PF10500.9 CCD26051.2 - 0.0018 17.9 20.9 0.0018 17.9 20.9 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF4820 PF16091.5 CCD26051.2 - 0.53 9.6 5.4 1.1 8.6 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CHORD PF04968.12 CCD26052.2 - 0.0049 17.6 4.6 0.011 16.4 4.6 1.6 1 0 0 1 1 1 1 CHORD DNA_pol_A_exo1 PF01612.20 CCD26052.2 - 0.078 12.7 0.5 0.8 9.4 0.5 2.5 1 1 0 1 1 1 0 3'-5' exonuclease AAA_5 PF07728.14 CCD26053.2 - 5e-125 412.0 1.7 3e-21 75.9 0.0 10.0 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CCD26053.2 - 1.4e-53 179.6 0.4 9.3e-21 74.0 0.0 5.5 5 0 0 5 5 4 3 Midasin AAA lid domain AAA_7 PF12775.7 CCD26053.2 - 5.1e-33 114.1 7.5 3e-07 30.1 0.0 7.0 7 0 0 7 7 6 6 P-loop containing dynein motor region AAA_3 PF07726.11 CCD26053.2 - 5e-32 110.5 0.0 1e-10 41.6 0.0 8.1 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 CCD26053.2 - 8.3e-32 109.4 0.0 1.1e-29 102.5 0.0 3.7 2 0 0 2 2 2 1 Midasin AAA lid domain AAA PF00004.29 CCD26053.2 - 1.2e-24 87.2 2.9 0.0011 19.4 0.0 7.8 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCD26053.2 - 2e-22 80.4 13.0 0.0055 17.1 0.3 9.1 8 2 1 9 9 8 6 AAA ATPase domain AAA_6 PF12774.7 CCD26053.2 - 5e-22 78.3 0.6 0.011 14.8 0.0 9.3 8 1 1 9 9 9 5 Hydrolytic ATP binding site of dynein motor region Dynein_heavy PF03028.15 CCD26053.2 - 1.2e-21 77.0 0.1 9.3e-06 25.7 0.0 8.1 8 1 0 8 8 7 3 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 CCD26053.2 - 2.7e-19 69.5 0.4 0.00076 19.2 0.0 6.3 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_22 PF13401.6 CCD26053.2 - 1.3e-15 57.9 0.3 0.15 12.3 0.0 8.5 8 0 0 8 8 6 2 AAA domain Sigma54_activ_2 PF14532.6 CCD26053.2 - 6.4e-15 55.5 1.0 0.0022 18.1 0.1 7.4 7 0 0 7 7 7 2 Sigma-54 interaction domain AAA_30 PF13604.6 CCD26053.2 - 7.7e-15 55.1 0.3 0.15 11.8 0.5 8.0 7 1 0 7 7 7 3 AAA domain AAA_14 PF13173.6 CCD26053.2 - 9.1e-15 54.9 5.8 0.01 15.9 0.0 8.8 7 1 1 8 8 7 2 AAA domain TsaE PF02367.17 CCD26053.2 - 1.7e-14 53.9 3.7 0.046 13.7 0.1 6.8 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 CCD26053.2 - 1.8e-12 46.9 5.5 0.056 12.5 0.0 6.2 6 0 0 6 6 6 3 Type II/IV secretion system protein Zeta_toxin PF06414.12 CCD26053.2 - 3.7e-12 45.9 4.8 0.012 14.9 0.0 7.9 9 0 0 9 9 9 2 Zeta toxin RsgA_GTPase PF03193.16 CCD26053.2 - 6.1e-12 45.8 7.7 0.061 13.2 0.3 6.7 6 0 0 6 6 6 3 RsgA GTPase AAA_33 PF13671.6 CCD26053.2 - 2.8e-10 40.5 0.3 0.075 13.2 0.1 6.8 6 0 0 6 6 6 1 AAA domain AAA_25 PF13481.6 CCD26053.2 - 4e-10 39.6 0.3 0.09 12.3 0.0 5.4 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.6 CCD26053.2 - 8.4e-10 38.3 0.7 1.9 8.3 0.0 6.4 6 0 0 6 6 6 2 P-loop containing region of AAA domain AAA_19 PF13245.6 CCD26053.2 - 2.4e-09 37.7 1.8 0.2 12.0 0.0 5.9 6 0 0 6 6 4 2 AAA domain Mg_chelatase PF01078.21 CCD26053.2 - 5e-09 35.8 3.1 4.8 6.5 0.0 8.9 10 1 1 11 11 10 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CCD26053.2 - 3.1e-08 33.5 2.1 0.44 10.3 0.0 5.7 7 0 0 7 7 5 2 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CCD26053.2 - 3.6e-08 33.6 5.8 0.91 9.4 0.1 6.7 6 0 0 6 6 6 1 Rad17 P-loop domain PduV-EutP PF10662.9 CCD26053.2 - 4.6e-08 32.9 1.8 0.062 13.1 0.1 6.0 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 CCD26053.2 - 5.5e-08 32.4 2.3 0.12 11.8 0.0 6.0 6 0 0 6 6 6 2 Bacterial TniB protein AAA_18 PF13238.6 CCD26053.2 - 5.6e-08 33.4 28.4 0.051 14.1 0.0 10.1 10 1 0 10 10 7 2 AAA domain ABC_tran PF00005.27 CCD26053.2 - 1e-07 32.5 43.1 0.0011 19.4 0.0 9.0 10 0 0 10 10 6 4 ABC transporter RNA_helicase PF00910.22 CCD26053.2 - 1.1e-07 32.2 13.3 1.2 9.6 0.1 8.0 9 0 0 9 9 6 2 RNA helicase DUF815 PF05673.13 CCD26053.2 - 1.1e-07 31.3 0.7 0.084 12.0 0.0 5.7 6 0 0 6 6 6 1 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 CCD26053.2 - 1.2e-07 31.8 6.1 1.9 8.6 0.1 7.1 6 0 0 6 6 6 1 50S ribosome-binding GTPase NACHT PF05729.12 CCD26053.2 - 1.2e-07 31.8 2.4 3.2 7.6 0.1 5.7 6 0 0 6 6 4 1 NACHT domain Roc PF08477.13 CCD26053.2 - 1.4e-07 31.7 4.2 2.3 8.4 0.1 6.8 6 0 0 6 6 6 1 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 CCD26053.2 - 2.5e-07 30.6 0.1 1.8 8.3 0.0 6.0 6 0 0 6 6 6 1 IstB-like ATP binding protein VWA PF00092.28 CCD26053.2 - 1.1e-05 25.7 2.4 2.3e-05 24.7 0.7 2.6 2 0 0 2 2 1 1 von Willebrand factor type A domain SRP54 PF00448.22 CCD26053.2 - 3.7e-05 23.4 7.3 0.43 10.2 0.4 5.4 5 0 0 5 5 4 1 SRP54-type protein, GTPase domain PhoH PF02562.16 CCD26053.2 - 7.1e-05 22.4 3.4 4.2 6.8 0.0 4.9 5 0 0 5 5 5 0 PhoH-like protein AAA_28 PF13521.6 CCD26053.2 - 0.00015 22.1 9.2 7 6.9 0.1 6.4 7 0 0 7 7 6 0 AAA domain ATP-synt_ab PF00006.25 CCD26053.2 - 0.00021 21.0 0.4 5 6.7 0.0 4.0 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.12 CCD26053.2 - 0.00051 19.9 0.9 22 4.8 0.0 5.9 5 1 0 5 5 5 0 Chloramphenicol phosphotransferase-like protein DEAD PF00270.29 CCD26053.2 - 0.0014 18.4 0.8 6.4 6.5 0.0 4.2 4 0 0 4 4 3 0 DEAD/DEAH box helicase ResIII PF04851.15 CCD26053.2 - 0.0031 17.5 10.5 5.3 7.0 0.0 5.6 4 1 0 4 4 4 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 CCD26053.2 - 0.0055 16.5 0.2 7.6 6.2 0.0 5.0 5 0 0 5 5 4 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 CCD26053.2 - 0.0065 16.3 10.5 2.8 7.7 0.4 6.2 7 0 0 7 7 6 1 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 CCD26053.2 - 0.0081 15.5 0.4 9.3 5.5 0.1 3.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 CCD26053.2 - 1.1 9.1 13.1 20 5.1 0.6 5.7 6 0 0 6 6 5 0 NTPase tRNA_int_endo PF01974.17 CCD26054.2 - 7.7e-23 80.4 0.1 1.6e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 CCD26054.2 - 0.073 12.8 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain DUF4014 PF13198.6 CCD26055.2 - 0.1 13.0 0.5 0.16 12.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) dCMP_cyt_deam_1 PF00383.23 CCD26056.2 - 2.9e-28 97.7 1.4 4.6e-28 97.0 1.4 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCD26056.2 - 1.6e-17 63.5 1.1 1.7e-16 60.2 0.2 2.2 2 0 0 2 2 2 1 MafB19-like deaminase SNAD4 PF18750.1 CCD26056.2 - 0.024 14.8 0.7 0.059 13.5 0.2 2.0 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 DUF2433 PF10360.9 CCD26056.2 - 0.1 12.7 0.2 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) APOBEC_N PF08210.11 CCD26056.2 - 0.2 11.5 1.9 0.31 10.9 1.1 1.9 1 1 0 1 1 1 0 APOBEC-like N-terminal domain Hyphal_reg_CWP PF11765.8 CCD26057.2 - 6.7e-18 64.7 25.3 3.5e-11 42.6 13.5 2.7 2 1 1 3 3 3 2 Hyphally regulated cell wall protein N-terminal Herpes_pp85 PF04637.12 CCD26057.2 - 0.96 7.8 6.4 1.5 7.2 6.4 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF5364 PF17322.2 CCD26058.2 - 0.00035 20.9 3.7 0.00035 20.9 3.7 2.5 2 0 0 2 2 2 1 Family of unknown function (DUF5364) CAMSAP_CC1 PF17095.5 CCD26058.2 - 0.064 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin PixA PF12306.8 CCD26058.2 - 1.9 8.6 5.9 0.39 10.9 0.6 2.3 2 0 0 2 2 2 0 Inclusion body protein Nuf2 PF03800.14 CCD26059.2 - 5.6e-42 143.2 1.1 5.6e-42 143.2 1.1 3.3 2 1 1 3 3 3 1 Nuf2 family DHR10 PF18595.1 CCD26059.2 - 0.00051 20.1 15.2 0.00051 20.1 15.2 4.2 2 1 2 4 4 4 1 Designed helical repeat protein 10 domain CENP-F_leu_zip PF10473.9 CCD26059.2 - 0.018 15.1 15.4 0.018 15.1 15.4 3.7 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 CCD26059.2 - 1.5 9.3 36.4 0.3 11.5 16.8 2.5 1 1 0 2 2 2 0 Fez1 Spc7 PF08317.11 CCD26059.2 - 2.8 6.7 45.4 0.01 14.7 18.0 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Cyclin_C PF02984.19 CCD26059.2 - 4.9 7.3 7.4 0.55 10.3 0.3 2.9 3 1 1 4 4 4 0 Cyclin, C-terminal domain DUF592 PF04574.13 CCD26060.2 - 8.1e-65 217.3 4.7 1.7e-64 216.2 4.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF592) SIR2 PF02146.17 CCD26060.2 - 4.6e-62 209.1 0.0 1.3e-61 207.6 0.0 1.8 2 0 0 2 2 2 1 Sir2 family TPP_enzyme_M PF00205.22 CCD26060.2 - 0.0016 18.2 0.0 0.99 9.1 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain PseudoU_synth_2 PF00849.22 CCD26061.2 - 2.8e-33 115.3 0.0 5.3e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase PQQ PF01011.21 CCD26061.2 - 0.17 11.9 0.1 0.66 10.0 0.1 2.0 1 0 0 1 1 1 0 PQQ enzyme repeat Exo_endo_phos PF03372.23 CCD26062.2 - 0.00051 19.6 0.0 0.0014 18.2 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Baculo_PEP_C PF04513.12 CCD26062.2 - 0.049 13.7 0.2 0.37 10.8 0.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Inositol_P PF00459.25 CCD26063.2 - 2.1e-55 188.2 0.1 2.8e-54 184.5 0.1 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family DEAD PF00270.29 CCD26064.2 - 1.4e-50 171.5 0.1 6.4e-49 166.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD26064.2 - 1e-23 83.8 0.4 2e-22 79.6 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CCD26064.2 - 5.9e-18 64.9 6.7 5.9e-18 64.9 6.7 3.5 3 0 0 3 3 3 1 DBP10CT (NUC160) domain RNA_pol_I_A49 PF06870.12 CCD26065.2 - 0.17 10.7 0.0 0.21 10.4 0.0 1.0 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor DUF3449 PF11931.8 CCD26066.2 - 5.8e-64 215.3 0.9 5.8e-64 215.3 0.9 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) PRP9_N PF16958.5 CCD26066.2 - 3e-50 170.2 15.6 3e-50 170.2 15.6 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor PRP9 N-terminus SF3A3 PF16837.5 CCD26066.2 - 1.9e-17 63.6 5.1 1.9e-17 63.6 5.1 2.8 3 0 0 3 3 3 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-met PF12874.7 CCD26066.2 - 2.3e-07 31.0 7.8 2.3e-05 24.6 4.3 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCD26066.2 - 7.4e-06 26.1 11.4 3.1e-05 24.1 2.6 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CCD26066.2 - 0.0034 17.7 4.3 0.19 12.1 0.8 2.8 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 CCD26066.2 - 0.006 16.3 1.3 0.018 14.8 1.3 1.9 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_4 PF13894.6 CCD26066.2 - 0.066 14.1 7.8 5.1 8.2 0.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-DBF PF07535.12 CCD26066.2 - 4 7.6 8.1 2 8.6 1.6 2.8 2 0 0 2 2 2 0 DBF zinc finger Actin PF00022.19 CCD26067.2 - 8.6e-111 370.4 0.0 2.8e-110 368.7 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CCD26067.2 - 0.014 14.2 0.0 0.074 11.9 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein CRT10 PF08728.10 CCD26068.2 - 5.2e-155 517.5 12.1 6.3e-155 517.2 12.1 1.1 1 0 0 1 1 1 1 CRT10 Adap_comp_sub PF00928.21 CCD26069.2 - 1.6e-75 253.9 0.4 2.2e-75 253.4 0.4 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Pribosyl_synth PF14572.6 CCD26070.2 - 2.9e-41 141.5 3.0 1e-39 136.5 3.0 2.3 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CCD26070.2 - 2.9e-35 120.7 0.0 9.3e-35 119.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CCD26070.2 - 5.2e-11 42.3 1.1 6.7e-10 38.7 1.1 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CCD26070.2 - 0.082 12.3 0.0 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase Adeno_PIX PF03955.14 CCD26070.2 - 0.099 12.8 2.7 0.085 13.0 0.8 1.8 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF21 PF01595.20 CCD26071.2 - 8.7e-33 113.5 0.8 1.7e-32 112.5 0.8 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CCD26071.2 - 0.00012 22.4 0.1 0.38 11.2 0.0 3.2 3 0 0 3 3 3 2 CBS domain Hyphal_reg_CWP PF11765.8 CCD26072.2 - 6.9e-08 31.8 8.5 8.1e-08 31.6 8.5 1.1 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal ATG2_CAD PF13329.6 CCD26072.2 - 0.043 13.5 0.1 0.059 13.1 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif Hyphal_reg_CWP PF11765.8 CCD26073.2 - 3.5e-49 167.5 21.0 3.5e-49 167.5 21.0 1.5 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal NAD_Gly3P_dh_N PF01210.23 CCD26074.2 - 1.8e-52 177.4 0.2 1.8e-52 177.4 0.2 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CCD26074.2 - 1.7e-40 138.6 0.1 3.9e-40 137.4 0.1 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 CCD26074.2 - 0.0017 18.9 0.1 0.054 14.1 0.1 2.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 CCD26074.2 - 0.024 15.1 0.1 0.063 13.7 0.1 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PDH PF02153.17 CCD26074.2 - 0.035 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase IlvN PF07991.12 CCD26074.2 - 0.036 13.6 0.1 0.25 10.9 0.0 2.3 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF3894 PF13033.6 CCD26074.2 - 0.35 11.0 2.1 0.69 10.1 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3894) Arginosuc_synth PF00764.19 CCD26075.2 - 3.6e-165 550.0 0.0 4.1e-165 549.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 CCD26075.2 - 0.00053 19.5 0.0 0.00099 18.7 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CCD26075.2 - 0.011 14.6 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase His_Phos_1 PF00300.22 CCD26076.2 - 1.9e-32 112.5 0.0 1.7e-15 57.2 0.0 3.1 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) zf-C2H2 PF00096.26 CCD26077.2 - 2.1e-06 27.8 2.4 0.0079 16.6 0.3 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD26077.2 - 0.0057 17.4 6.9 1.5 9.9 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCD26077.2 - 0.12 12.8 1.3 4.2 8.0 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 CCD26077.2 - 0.37 10.9 4.7 1.9 8.5 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CCD26077.2 - 3.9 8.2 6.4 5.4 7.7 3.6 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 CCD26077.2 - 4.3 7.2 5.6 7.1 6.5 0.0 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type Phos_pyr_kin PF08543.12 CCD26078.2 - 6.9e-80 268.0 0.3 9e-80 267.6 0.3 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 CCD26078.2 - 2.2e-60 204.1 0.3 3.1e-60 203.6 0.3 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.15 CCD26078.2 - 0.0013 18.2 0.2 0.0025 17.2 0.2 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family PfkB PF00294.24 CCD26078.2 - 0.0031 16.8 0.1 0.0089 15.4 0.1 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 CCD26078.2 - 0.14 11.7 0.1 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 Carbohydrate kinase Oxysterol_BP PF01237.18 CCD26079.2 - 7.5e-131 436.4 3.8 7.5e-131 436.4 3.8 3.0 2 1 1 4 4 4 1 Oxysterol-binding protein Ank_5 PF13857.6 CCD26079.2 - 5.2e-10 39.4 1.7 0.00072 19.8 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.29 CCD26079.2 - 1e-09 38.9 0.3 3.4e-09 37.2 0.3 2.0 1 0 0 1 1 1 1 PH domain Ank_2 PF12796.7 CCD26079.2 - 1.2e-09 38.6 0.2 0.00011 22.7 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCD26079.2 - 8e-09 35.9 0.1 0.0013 19.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCD26079.2 - 2.6e-08 33.5 0.2 0.046 14.3 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat PH_8 PF15409.6 CCD26079.2 - 1e-07 32.1 1.2 1.3e-06 28.6 0.1 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain Ank PF00023.30 CCD26079.2 - 2.5e-06 27.7 0.0 0.012 16.0 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat PH_11 PF15413.6 CCD26079.2 - 0.025 15.0 0.5 0.025 15.0 0.5 4.2 3 2 1 4 4 4 0 Pleckstrin homology domain Pkinase PF00069.25 CCD26080.2 - 1.1e-74 251.1 3.2 5.8e-74 248.8 0.1 2.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26080.2 - 5.9e-53 179.8 0.0 1.1e-52 178.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD26080.2 - 8e-05 22.1 0.0 0.00093 18.6 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CCD26080.2 - 0.037 12.8 3.4 0.23 10.2 3.4 2.4 1 1 0 1 1 1 0 Fungal protein kinase MRP-63 PF14978.6 CCD26080.2 - 1.4 9.5 5.5 0.3 11.8 0.7 2.5 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 Actin PF00022.19 CCD26081.2 - 9.2e-152 505.4 0.0 2.7e-151 503.8 0.0 1.6 1 1 0 1 1 1 1 Actin Ras PF00071.22 CCD26082.2 - 6.6e-65 217.7 0.4 7.9e-65 217.4 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD26082.2 - 7.3e-36 123.0 0.2 1.3e-35 122.2 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD26082.2 - 3.6e-17 62.4 0.2 4.7e-17 62.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCD26082.2 - 1.2e-05 24.7 0.3 1.7e-05 24.3 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CCD26082.2 - 1.3e-05 24.8 0.2 3.3e-05 23.5 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CCD26082.2 - 0.00025 21.1 0.1 0.00051 20.1 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CCD26082.2 - 0.0024 17.3 0.1 0.0041 16.6 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CCD26082.2 - 0.0042 17.0 0.7 0.11 12.4 0.1 2.3 1 1 1 2 2 2 1 RsgA GTPase Septin PF00735.18 CCD26082.2 - 0.043 13.1 0.2 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Septin AAA_5 PF07728.14 CCD26082.2 - 0.051 13.6 0.1 0.14 12.2 0.0 1.9 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CCD26082.2 - 0.051 14.1 2.1 0.55 10.7 2.1 2.1 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CCD26082.2 - 0.083 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CCD26082.2 - 0.088 13.2 0.0 0.15 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CCD26082.2 - 0.13 12.7 0.1 1.3 9.4 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCD26082.2 - 0.13 12.5 0.1 0.32 11.2 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 CCD26082.2 - 0.13 11.7 0.6 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_pol PF00940.19 CCD26083.2 - 9.6e-180 597.8 0.1 2.1e-179 596.7 0.1 1.6 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CCD26083.2 - 9.7e-100 334.2 0.9 9.7e-100 334.2 0.9 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal Mob1_phocein PF03637.17 CCD26084.2 - 2.7e-64 216.3 2.5 3.7e-64 215.8 2.5 1.2 1 0 0 1 1 1 1 Mob1/phocein family Methyltransf_12 PF08242.12 CCD26084.2 - 0.082 13.7 0.2 14 6.5 0.1 2.4 1 1 1 2 2 2 0 Methyltransferase domain Ribosomal_L22e PF01776.17 CCD26085.2 - 9.5e-38 128.9 0.5 1.4e-37 128.3 0.5 1.2 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF4799 PF16056.5 CCD26085.2 - 0.023 13.9 0.0 0.029 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4799) YqzE PF14038.6 CCD26085.2 - 0.097 12.7 1.5 3.1 7.9 0.1 2.4 2 0 0 2 2 2 0 YqzE-like protein DUF726 PF05277.12 CCD26086.2 - 2.1e-139 464.2 0.8 3.2e-139 463.6 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) tRNA_synthFbeta PF17759.1 CCD26087.2 - 2.4e-41 141.5 0.0 4.4e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CCD26087.2 - 2.5e-29 101.3 1.7 9.4e-29 99.5 0.3 2.3 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 CCD26087.2 - 2.2e-25 89.4 0.0 3.7e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 CCD26087.2 - 4.5e-16 58.9 0.0 2.9e-14 53.1 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetase B5 domain Pkinase PF00069.25 CCD26088.2 - 5.8e-61 206.2 0.0 1.5e-37 129.4 0.4 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26088.2 - 2.4e-26 92.6 0.0 5e-21 75.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 CCD26088.2 - 9.1e-06 25.8 0.0 2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 CCD26088.2 - 0.00013 21.4 0.0 0.02 14.2 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CCD26088.2 - 0.00063 19.7 0.1 0.086 12.8 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CCD26088.2 - 0.0016 18.1 0.2 1.5 8.4 0.0 3.2 2 1 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CCD26088.2 - 0.0026 17.1 0.1 0.0047 16.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CCD26088.2 - 0.023 14.3 0.6 0.11 12.1 0.6 2.0 1 1 0 1 1 1 0 RIO1 family PAS PF00989.25 CCD26088.2 - 0.035 14.1 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 PAS fold bZIP_1 PF00170.21 CCD26089.2 - 2.3e-05 24.4 6.5 4.6e-05 23.4 6.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CCD26089.2 - 0.0011 19.0 7.8 0.0011 19.0 7.8 1.8 1 1 0 1 1 1 1 Basic region leucine zipper HTH_25 PF13413.6 CCD26089.2 - 0.085 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain GnHR_trans PF12369.8 CCD26089.2 - 0.16 12.8 0.3 0.16 12.8 0.3 2.2 2 0 0 2 2 2 0 Gonadotropin hormone receptor transmembrane region Aminotran_5 PF00266.19 CCD26090.2 - 4.2e-23 81.9 0.0 5.5e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V SHMT PF00464.19 CCD26091.2 - 3.3e-206 684.6 0.0 3.8e-206 684.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 CCD26091.2 - 4.1e-07 29.5 0.0 1.1e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CCD26091.2 - 0.00038 19.8 0.0 0.00063 19.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 CCD26091.2 - 0.00058 18.9 0.0 0.00085 18.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cytochrom_B562 PF07361.11 CCD26091.2 - 0.17 12.5 2.7 0.27 11.9 0.6 2.2 2 0 0 2 2 2 0 Cytochrome b562 Pkinase PF00069.25 CCD26092.2 - 3.9e-25 88.7 0.3 1.9e-24 86.5 0.2 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26092.2 - 1.9e-14 53.6 0.0 2.7e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCD26092.2 - 0.00087 18.2 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CCD26092.2 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCD26092.2 - 0.011 15.1 0.0 0.069 12.5 0.0 2.0 2 0 0 2 2 2 0 Kinase-like YrbL-PhoP_reg PF10707.9 CCD26092.2 - 0.033 13.7 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 CCD26092.2 - 0.093 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC_tran PF00005.27 CCD26093.2 - 1.2e-18 67.9 0.0 2.3e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CCD26093.2 - 4.9e-10 39.7 2.4 0.00056 19.8 0.1 2.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCD26093.2 - 2.3e-06 27.2 0.0 0.017 14.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCD26093.2 - 0.00079 19.1 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CCD26093.2 - 0.002 17.9 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 CCD26093.2 - 0.0025 18.4 0.1 0.0046 17.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CCD26093.2 - 0.0068 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 CCD26093.2 - 0.0099 16.4 0.1 0.021 15.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CCD26093.2 - 0.035 14.2 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 CCD26093.2 - 0.046 13.8 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA PF00004.29 CCD26093.2 - 0.05 14.0 0.3 1.4 9.3 0.2 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3584 PF12128.8 CCD26093.2 - 0.064 10.8 0.1 0.084 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FtsK_SpoIIIE PF01580.18 CCD26093.2 - 0.084 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_27 PF13514.6 CCD26093.2 - 0.12 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CCD26093.2 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CCD26093.2 - 0.15 12.5 0.2 0.23 11.9 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain MutS_V PF00488.21 CCD26093.2 - 0.15 12.1 0.1 12 5.8 0.0 2.4 2 0 0 2 2 2 0 MutS domain V Zeta_toxin PF06414.12 CCD26093.2 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 CCD26093.2 - 0.19 11.4 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RabGAP-TBC PF00566.18 CCD26094.2 - 3.6e-12 46.4 12.4 2.4e-11 43.7 12.4 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain NTase_sub_bind PF08780.11 CCD26094.2 - 0.086 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like STE2 PF02116.15 CCD26095.2 - 6.2e-90 301.3 23.0 7.5e-90 301.0 23.0 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF2976 PF11190.8 CCD26095.2 - 0.13 12.1 6.8 0.27 11.0 2.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Mannosyl_trans4 PF15971.5 CCD26095.2 - 0.27 11.1 7.4 0.14 12.0 3.3 2.4 2 1 0 2 2 2 0 DolP-mannose mannosyltransferase DUF412 PF04217.13 CCD26095.2 - 0.51 10.2 6.0 2.4 8.1 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF412 PGAP1 PF07819.13 CCD26096.2 - 2.1e-95 318.8 0.0 3.7e-95 318.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CCD26096.2 - 0.0011 19.7 0.0 0.0018 18.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CCD26096.2 - 0.029 14.0 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 CCD26096.2 - 0.044 13.6 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 CCD26096.2 - 0.12 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCD26096.2 - 0.19 10.9 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 EPL1 PF10513.9 CCD26097.2 - 3.3e-25 89.3 4.5 3.3e-25 89.3 4.5 3.7 4 1 0 4 4 4 1 Enhancer of polycomb-like DUF3835 PF12927.7 CCD26098.2 - 8.6e-17 61.8 0.3 8.6e-17 61.8 0.3 6.1 6 0 0 6 6 6 2 Domain of unknown function (DUF3835) Prefoldin PF02996.17 CCD26098.2 - 1.2e-12 47.8 0.5 1.2e-12 47.8 0.5 3.4 3 0 0 3 3 3 1 Prefoldin subunit GCR1_C PF12550.8 CCD26099.2 - 7e-09 35.9 0.8 5.1e-08 33.1 0.4 2.3 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes MnmE_helical PF12631.7 CCD26099.2 - 0.082 13.1 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 MnmE helical domain tRNA-synt_2d PF01409.20 CCD26100.2 - 1.6e-91 306.2 0.0 2.1e-91 305.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 CCD26100.2 - 2.2e-12 47.1 1.8 2.2e-12 47.1 1.8 2.4 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 CCD26100.2 - 2.8e-08 33.5 0.0 2e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 CCD26100.2 - 3.1e-06 27.1 2.8 1.2e-05 25.2 2.8 2.2 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 CCD26100.2 - 3.9e-05 23.7 0.0 7.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 CCD26100.2 - 6.1e-05 22.2 0.1 0.0016 17.5 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_His PF13393.6 CCD26100.2 - 0.0063 15.8 0.1 0.041 13.1 0.0 2.0 2 0 0 2 2 2 1 Histidyl-tRNA synthetase P_gingi_FimA PF06321.11 CCD26101.2 - 0.049 13.7 0.6 0.14 12.3 0.1 1.9 1 1 1 2 2 2 0 Major fimbrial subunit protein (FimA) GATA PF00320.27 CCD26102.2 - 1.6e-15 56.4 4.2 3.4e-15 55.4 4.2 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 CCD26102.2 - 2.1e-07 30.7 0.5 5.1e-07 29.4 0.5 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 CCD26102.2 - 0.045 13.3 0.8 0.12 11.9 0.8 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 CCD26102.2 - 0.19 11.7 1.0 0.4 10.6 1.0 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-piccolo PF05715.13 CCD26102.2 - 2.2 8.5 5.0 9.6 6.4 5.0 2.1 1 1 0 1 1 1 0 Piccolo Zn-finger LSM PF01423.22 CCD26103.2 - 1.3e-18 66.4 0.1 1.4e-18 66.3 0.1 1.0 1 0 0 1 1 1 1 LSM domain Acetyltransf_1 PF00583.25 CCD26104.2 - 1.5e-14 54.2 0.1 1.7e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CCD26104.2 - 8e-11 42.2 0.1 1.1e-10 41.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CCD26104.2 - 1.4e-08 34.7 0.0 1.5e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CCD26104.2 - 0.02 15.0 0.2 0.045 13.9 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CCD26104.2 - 0.034 14.2 0.1 0.12 12.4 0.1 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DnaJ PF00226.31 CCD26105.2 - 5.6e-26 90.5 5.0 1.3e-25 89.2 5.0 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 CCD26105.2 - 6e-25 88.1 0.1 1e-24 87.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CCD26105.2 - 6.4e-14 52.1 16.5 1.3e-13 51.1 16.5 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 CCD26105.2 - 0.012 15.7 7.2 0.5 10.4 1.0 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrom_c3_2 PF14537.6 CCD26105.2 - 0.13 12.8 12.4 0.96 10.0 3.3 2.6 1 1 1 2 2 2 0 Cytochrome c3 Anti-TRAP PF15777.5 CCD26105.2 - 1.4 9.0 14.3 1.7 8.7 5.4 2.7 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn_Tnp_IS1595 PF12760.7 CCD26105.2 - 1.4 8.9 6.2 0.76 9.8 3.1 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf_CopZ PF18423.1 CCD26105.2 - 7 6.7 6.0 2.1 8.4 0.3 2.6 2 1 0 2 2 2 0 Zinc binding domain zf-TFIIB PF13453.6 CCD26105.2 - 9 5.7 10.5 1.7 8.0 2.7 3.0 3 0 0 3 3 3 0 Transcription factor zinc-finger DZR PF12773.7 CCD26105.2 - 9.9 6.3 9.9 28 4.8 0.8 2.3 1 1 1 2 2 2 0 Double zinc ribbon HSP9_HSP12 PF04119.12 CCD26106.2 - 1.9e-28 98.6 6.2 2.1e-27 95.3 1.5 2.1 2 0 0 2 2 2 2 Heat shock protein 9/12 YtxH PF12732.7 CCD26106.2 - 0.06 13.9 7.2 4.2 8.0 7.2 2.6 1 1 0 1 1 1 0 YtxH-like protein DUF4786 PF16027.5 CCD26107.2 - 2.3 8.7 0.0 2.3 8.7 0.0 4.0 3 2 0 3 3 3 0 Domain of unknown function (DUF4786) WD40 PF00400.32 CCD26108.2 - 1.7e-34 117.2 18.9 7.3e-07 29.8 0.1 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat CDC4_D PF16856.5 CCD26108.2 - 7.8e-19 67.3 9.7 3.7e-18 65.1 9.7 2.3 1 0 0 1 1 1 1 Cell division control protein 4 dimerisation domain F-box-like PF12937.7 CCD26108.2 - 4.1e-11 42.6 0.5 1.1e-10 41.2 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CCD26108.2 - 1.2e-07 31.4 1.6 1.3e-07 31.3 0.3 1.8 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 CCD26108.2 - 0.00022 21.5 0.5 0.43 10.9 0.0 4.4 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain SMC_N PF02463.19 CCD26109.2 - 4.7e-52 176.6 64.7 2.3e-51 174.3 64.7 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CCD26109.2 - 3.8e-25 88.5 0.0 2.1e-24 86.1 0.0 2.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CCD26109.2 - 8.5e-16 59.1 20.1 8.5e-16 59.1 20.1 7.1 3 2 3 6 6 3 1 AAA domain AAA_21 PF13304.6 CCD26109.2 - 1.9e-09 37.7 1.6 8.1e-06 25.8 0.0 4.9 3 2 2 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CCD26109.2 - 2e-08 34.4 46.1 2e-08 34.4 46.1 4.7 2 2 2 4 4 2 1 AAA ATPase domain AAA_29 PF13555.6 CCD26109.2 - 2.2e-08 33.7 0.1 4.8e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain HrpB7 PF09486.10 CCD26109.2 - 0.0047 17.3 1.4 0.0047 17.3 1.4 7.3 5 3 2 8 8 8 2 Bacterial type III secretion protein (HrpB7) SlyX PF04102.12 CCD26109.2 - 0.018 15.6 2.4 0.018 15.6 2.4 8.4 8 2 2 10 10 8 0 SlyX AAA_27 PF13514.6 CCD26109.2 - 0.072 12.7 0.0 0.072 12.7 0.0 6.5 7 1 1 8 8 8 0 AAA domain ABC_tran PF00005.27 CCD26109.2 - 0.085 13.4 0.0 0.085 13.4 0.0 6.1 3 2 0 3 3 1 0 ABC transporter Complex1_49kDa PF00346.19 CCD26109.2 - 0.37 9.8 3.4 0.97 8.5 0.0 3.3 4 0 0 4 4 4 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit HisKA_3 PF07730.13 CCD26109.2 - 0.69 10.5 14.3 8.8 6.9 0.7 5.2 5 1 0 5 5 4 0 Histidine kinase AAA_22 PF13401.6 CCD26109.2 - 4.7 7.5 10.1 21 5.4 0.0 4.6 5 1 0 5 5 5 0 AAA domain BLM10_mid PF16507.5 CCD26110.2 - 3.1e-165 550.8 13.9 6.1e-165 549.8 13.9 1.5 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region BLM10_N PF16547.5 CCD26110.2 - 1.2e-30 105.6 1.0 4.1e-30 103.9 1.0 2.0 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal DUF3437 PF11919.8 CCD26110.2 - 1.5e-25 88.9 0.0 1.1e-24 86.2 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) Stork_head PF10264.9 CCD26110.2 - 0.11 12.6 1.2 6.7 7.0 0.2 3.4 3 0 0 3 3 3 0 Winged helix Storkhead-box1 domain DUF2569 PF10754.9 CCD26110.2 - 0.3 11.5 5.1 1.2 9.5 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2569) Ras PF00071.22 CCD26111.2 - 1.5e-63 213.2 0.4 1.8e-63 213.0 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD26111.2 - 2.8e-37 127.6 0.3 4.1e-37 127.1 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD26111.2 - 3.5e-19 68.9 0.2 4e-19 68.7 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CCD26111.2 - 2.6e-07 30.2 0.2 3.3e-07 29.9 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CCD26111.2 - 6.5e-07 28.9 0.1 7.4e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCD26111.2 - 1.9e-06 27.9 0.1 2.9e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCD26111.2 - 4.5e-06 26.7 0.2 0.089 12.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CCD26111.2 - 2e-05 24.3 0.3 0.00035 20.2 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CCD26111.2 - 0.0067 16.0 0.1 0.076 12.5 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.6 CCD26111.2 - 0.022 14.5 0.1 0.11 12.3 0.1 2.1 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CCD26111.2 - 0.023 14.2 0.0 0.055 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 CCD26111.2 - 0.041 14.1 0.1 0.14 12.4 0.0 2.1 1 1 1 2 2 2 0 AAA domain MCM PF00493.23 CCD26111.2 - 0.051 12.7 0.0 0.12 11.4 0.0 1.6 2 1 0 2 2 2 0 MCM P-loop domain AAA_16 PF13191.6 CCD26111.2 - 0.1 12.9 0.1 0.26 11.7 0.0 1.7 1 1 1 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.9 CCD26111.2 - 0.11 12.2 0.0 0.41 10.4 0.0 1.9 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation VTC PF09359.10 CCD26112.2 - 2.5e-91 305.9 0.7 7e-91 304.4 0.7 1.8 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 CCD26112.2 - 4.1e-15 56.6 25.3 0.00015 21.8 0.0 5.0 4 1 1 5 5 5 4 SPX domain DUF202 PF02656.15 CCD26112.2 - 9.3e-11 42.0 1.3 1.4e-10 41.5 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2975 PF11188.8 CCD26112.2 - 0.018 14.9 0.8 0.029 14.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Methyltransf_10 PF05971.12 CCD26112.2 - 0.077 12.3 0.1 1.8 7.8 0.0 2.5 3 0 0 3 3 3 0 RNA methyltransferase YqfQ PF14181.6 CCD26112.2 - 2.4 8.3 4.5 6.4 6.9 4.5 1.7 1 0 0 1 1 1 0 YqfQ-like protein PI3K_1B_p101 PF10486.9 CCD26112.2 - 2.8 5.6 7.4 0.16 9.7 1.6 1.6 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MutS_V PF00488.21 CCD26113.2 - 1.2e-50 172.2 0.0 3.9e-50 170.5 0.0 1.9 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CCD26113.2 - 1.4e-26 93.9 3.5 1.4e-26 93.9 3.5 1.8 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 CCD26113.2 - 1.2e-12 48.3 0.3 3.1e-12 46.9 0.3 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 CCD26113.2 - 3.3e-09 37.0 1.9 6.3e-09 36.1 0.1 2.5 2 0 0 2 2 2 1 MutS family domain IV AAA_30 PF13604.6 CCD26113.2 - 0.0018 18.1 0.0 0.16 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_pol_Rpb1_6 PF04992.14 CCD26113.2 - 0.077 12.8 3.5 0.18 11.6 1.6 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 6 NACHT PF05729.12 CCD26113.2 - 0.14 12.0 0.5 1.4 8.8 0.1 2.7 2 1 0 2 2 2 0 NACHT domain Chaperone_III PF07824.12 CCD26113.2 - 0.45 10.8 2.8 5.1 7.4 0.0 3.4 2 1 1 3 3 3 0 Type III secretion chaperone domain RT_RNaseH PF17917.1 CCD26114.2 - 1.3e-22 80.0 0.0 6.8e-22 77.7 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CCD26114.2 - 4.6e-17 61.9 0.0 3.8e-09 36.5 0.0 2.8 2 1 1 3 3 3 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 CCD26114.2 - 1.6e-15 57.4 0.0 5.3e-15 55.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CCD26114.2 - 7.2e-15 55.1 1.3 9.3e-15 54.7 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CCD26114.2 - 1.4e-08 34.7 2.8 1.4e-08 34.7 0.9 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 CCD26114.2 - 0.04 14.1 0.2 0.12 12.6 0.2 1.9 1 0 0 1 1 1 0 H2C2 zinc finger gag-asp_proteas PF13975.6 CCD26115.2 - 0.00096 19.7 0.0 0.0021 18.6 0.0 1.6 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp PF00026.23 CCD26115.2 - 0.0042 16.6 0.0 0.0066 15.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease RVP PF00077.20 CCD26115.2 - 0.005 17.1 0.1 0.018 15.3 0.1 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CCD26115.2 - 0.0094 16.6 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.8 CCD26115.2 - 0.012 15.1 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase Asp_protease PF09668.10 CCD26115.2 - 0.08 12.7 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease Nore1-SARAH PF16517.5 CCD26116.2 - 0.033 14.1 0.6 0.11 12.5 0.6 1.8 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain NFACT-C PF11923.8 CCD26117.2 - 2.1e-31 108.0 1.4 2.1e-31 108.0 1.4 3.9 2 1 1 3 3 3 1 NFACT protein C-terminal domain FbpA PF05833.11 CCD26117.2 - 2e-21 76.3 40.8 2e-21 76.3 40.8 3.7 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 CCD26117.2 - 3.1e-20 72.8 0.3 3.1e-20 72.8 0.3 2.6 2 0 0 2 2 2 1 NFACT protein RNA binding domain Alpha-mann_mid PF09261.11 CCD26117.2 - 0.076 13.2 0.2 0.076 13.2 0.2 2.7 2 0 0 2 2 2 0 Alpha mannosidase middle domain 2-Hacid_dh_C PF02826.19 CCD26118.2 - 1.2e-29 102.9 0.0 2.8e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CCD26118.2 - 5.9e-09 35.7 0.0 2.1e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ApbA PF02558.16 CCD26118.2 - 0.016 14.8 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AdoHcyase_NAD PF00670.21 CCD26118.2 - 0.082 13.0 0.2 9.4 6.3 0.0 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 CCD26118.2 - 0.17 11.4 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 CCD26118.2 - 0.18 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase zf-C2H2 PF00096.26 CCD26119.2 - 8.4e-12 44.9 13.4 5.6e-06 26.5 1.9 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD26119.2 - 9.4e-09 35.4 10.5 0.00053 20.6 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCD26119.2 - 3e-07 30.5 4.2 0.0044 17.3 0.4 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CCD26119.2 - 1.4e-06 28.5 13.4 1.7e-05 25.1 3.4 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 CCD26119.2 - 3.9e-05 23.9 9.3 0.0042 17.4 1.1 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CCD26119.2 - 6.2e-05 22.9 10.2 0.00084 19.3 0.9 2.7 2 1 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 CCD26119.2 - 0.0024 17.9 3.7 0.4 10.8 0.4 2.9 2 0 0 2 2 2 2 BED zinc finger zf-Di19 PF05605.12 CCD26119.2 - 0.0049 17.1 2.0 0.015 15.6 2.0 1.8 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CCD26119.2 - 0.026 14.9 5.7 1.1 9.6 0.4 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2115 PF09888.9 CCD26119.2 - 0.044 14.3 2.3 1.9 9.0 0.1 3.2 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) zf-LYAR PF08790.11 CCD26119.2 - 0.25 11.3 2.6 4.7 7.2 0.3 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_5 PF13909.6 CCD26119.2 - 0.27 11.0 9.0 1 9.2 0.8 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF2225 PF09986.9 CCD26119.2 - 0.48 10.1 4.2 5.8 6.6 0.2 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2HE PF16278.5 CCD26119.2 - 0.59 10.6 8.8 1.2 9.7 0.3 3.5 3 1 1 4 4 3 0 C2HE / C2H2 / C2HC zinc-binding finger DUF629 PF04780.12 CCD26119.2 - 0.86 8.1 7.2 4.2 5.8 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF629) GAGA PF09237.11 CCD26119.2 - 1.1 9.1 8.0 0.75 9.6 0.1 2.5 1 1 1 2 2 2 0 GAGA factor Mnd1 PF03962.15 CCD26120.2 - 3.2e-23 81.8 0.7 3.2e-23 81.8 0.7 2.7 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 CCD26120.2 - 1.4e-07 31.5 0.8 1.4e-07 31.5 0.8 2.4 2 0 0 2 2 2 1 Leucine zipper with capping helix domain Med9 PF07544.13 CCD26120.2 - 0.12 12.5 4.0 0.13 12.4 1.9 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ArfGap PF01412.18 CCD26121.2 - 1.4e-30 105.7 1.3 2.1e-30 105.2 0.0 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.31 CCD26121.2 - 0.048 13.6 0.0 0.14 12.1 0.0 1.9 1 1 0 1 1 1 0 UBA/TS-N domain TFIIA PF03153.13 CCD26121.2 - 1.6 8.6 26.1 2.6 8.0 26.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3543 PF12063.8 CCD26122.2 - 1e-86 290.4 11.7 3.2e-86 288.8 11.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 CCD26122.2 - 7.1e-56 189.5 0.8 1.9e-55 188.1 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26122.2 - 5.5e-43 147.1 0.0 1.1e-42 146.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase SRP1_TIP1 PF00660.17 CCD26123.2 - 5.2e-17 61.7 0.0 6.5e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family Pkinase PF00069.25 CCD26124.2 - 1.6e-57 194.9 0.0 2.8e-57 194.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26124.2 - 7.5e-28 97.5 0.0 1.3e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCD26124.2 - 9e-06 24.7 0.2 3.2e-05 22.9 0.1 1.9 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CCD26124.2 - 1.1e-05 25.0 0.0 6.8e-05 22.3 0.0 2.2 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 CCD26124.2 - 0.022 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PUF PF00806.19 CCD26125.2 - 1.1e-54 179.1 27.5 1.1e-07 31.2 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Vta1 PF04652.16 CCD26125.2 - 0.092 12.7 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Vta1 like Bud13 PF09736.9 CCD26128.2 - 7.9e-21 75.0 11.3 1.8e-18 67.4 0.5 3.2 2 2 1 3 3 3 2 Pre-mRNA-splicing factor of RES complex W_rich_C PF07483.11 CCD26128.2 - 0.012 15.7 0.9 0.028 14.5 0.9 1.7 1 0 0 1 1 1 0 Tryptophan-rich Synechocystis species C-terminal domain DUF3492 PF11997.8 CCD26128.2 - 0.76 9.5 7.2 0.13 12.0 2.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3492) XRN_N PF03159.18 CCD26129.2 - 8.8e-95 316.7 0.1 2e-94 315.6 0.1 1.6 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CCD26129.2 - 1.1e-86 291.6 5.2 1.1e-86 291.6 5.2 3.7 4 1 1 5 5 5 1 Xrn1 helical domain XRN1_D1 PF18332.1 CCD26129.2 - 1.7e-67 226.9 0.1 1.7e-67 226.9 0.1 2.6 3 0 0 3 3 3 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 CCD26129.2 - 9.9e-32 109.0 0.0 4.3e-31 107.0 0.0 2.2 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 CCD26129.2 - 1e-19 70.4 0.1 2.2e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 CCD26129.2 - 2e-19 69.4 3.0 2.5e-19 69.1 0.9 2.3 2 0 0 2 2 2 1 Exoribonuclease 1 Domain-3 Nucleoporin_FG PF13634.6 CCD26130.2 - 4e-26 91.7 145.3 2.1e-08 34.9 42.1 5.5 2 1 3 5 5 5 4 Nucleoporin FG repeat region DUF1664 PF07889.12 CCD26130.2 - 0.065 13.3 3.4 0.61 10.1 1.3 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) ATP-synt_G PF04718.15 CCD26131.2 - 3.5e-30 104.8 0.8 4.9e-30 104.3 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit MCM PF00493.23 CCD26132.2 - 6e-100 332.9 0.0 9.1e-100 332.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCD26132.2 - 5.3e-36 123.2 0.3 1.1e-35 122.3 0.3 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCD26132.2 - 2.7e-29 101.4 1.9 6.5e-29 100.2 1.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CCD26132.2 - 2.1e-17 63.6 5.6 8.7e-17 61.6 5.6 2.2 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 CCD26132.2 - 1.3e-05 25.2 0.0 7.3e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CCD26132.2 - 1.7e-05 24.3 0.0 0.00063 19.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CCD26132.2 - 0.0011 18.8 0.0 0.01 15.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCD26132.2 - 0.0084 16.5 0.9 1.2 9.5 0.1 3.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_lid_2 PF17863.1 CCD26132.2 - 0.059 13.2 0.2 0.18 11.7 0.2 1.7 1 0 0 1 1 1 0 AAA lid domain NDUFB10 PF10249.9 CCD26132.2 - 0.12 12.9 0.4 0.29 11.6 0.4 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Mnd1 PF03962.15 CCD26132.2 - 0.15 12.3 2.8 0.56 10.5 0.1 2.9 2 0 0 2 2 2 0 Mnd1 HTH domain Sigma54_activat PF00158.26 CCD26132.2 - 0.18 11.5 1.5 3.5 7.3 0.0 3.3 4 0 0 4 4 4 0 Sigma-54 interaction domain CAF1A PF12253.8 CCD26133.2 - 1.7e-22 79.4 8.1 1.7e-22 79.4 8.1 4.3 4 1 1 5 5 5 1 Chromatin assembly factor 1 subunit A zf-C4H2 PF10146.9 CCD26135.2 - 0.17 12.1 6.5 0.35 11.2 2.8 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Med4 PF10018.9 CCD26135.2 - 0.93 9.1 8.1 2.9 7.5 7.9 1.8 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 rve PF00665.26 CCD26136.2 - 3.6e-14 53.0 0.1 7.5e-14 52.0 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 CCD26136.2 - 0.0075 16.4 2.3 0.0075 16.3 0.7 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 CCD26136.2 - 0.064 13.0 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain RNA_pol_Rpb2_6 PF00562.28 CCD26137.2 - 1.6e-113 379.7 0.0 3.1e-113 378.8 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CCD26137.2 - 1.4e-45 155.3 0.1 2e-45 154.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CCD26137.2 - 3.7e-37 127.8 0.0 8.1e-37 126.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 CCD26137.2 - 6e-28 96.8 0.0 1.7e-27 95.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 CCD26137.2 - 5.3e-24 84.0 0.0 1.1e-23 83.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 CCD26137.2 - 3.9e-16 59.2 0.3 1.2e-14 54.5 0.0 2.7 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 7 E1-E2_ATPase PF00122.20 CCD26138.2 - 1.7e-48 164.6 1.4 2e-48 164.3 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CCD26138.2 - 4.7e-47 160.0 1.7 4.7e-47 160.0 1.7 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CCD26138.2 - 1.5e-20 73.1 0.0 3e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CCD26138.2 - 2.1e-19 70.7 0.3 1.3e-18 68.1 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CCD26138.2 - 4.1e-16 58.4 0.0 1.2e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CCD26138.2 - 2.8e-05 24.0 0.9 0.0014 18.4 0.6 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3784 PF12650.7 CCD26138.2 - 0.04 14.1 2.5 2.8 8.2 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) SPC12 PF06645.13 CCD26138.2 - 0.39 10.9 1.4 1.6 8.9 1.4 2.1 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Sua5_yciO_yrdC PF01300.18 CCD26139.2 - 2.3e-47 160.8 0.0 4.9e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 CCD26139.2 - 4.1e-25 88.9 0.0 6.6e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding PgaD PF13994.6 CCD26142.2 - 0.024 14.7 2.5 9 6.3 0.5 3.4 3 0 0 3 3 3 0 PgaD-like protein Intron_maturas2 PF01348.21 CCD26142.2 - 0.064 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Type II intron maturase Zn_clus PF00172.18 CCD26143.2 - 0.011 15.9 3.9 0.011 15.9 3.9 2.8 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DCP1 PF06058.13 CCD26144.2 - 2.9e-24 85.2 0.2 3.5e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 Dcp1-like decapping family Spt20 PF12090.8 CCD26146.2 - 2.5e-69 233.4 38.4 2.5e-69 233.4 38.4 6.0 4 2 1 5 5 5 1 Spt20 family DUF4598 PF15370.6 CCD26146.2 - 0.015 15.8 5.0 0.015 15.8 5.0 4.2 3 2 1 4 4 4 0 Domain of unknown function (DUF4598) PSD4 PF07631.11 CCD26146.2 - 0.57 10.7 6.1 0.083 13.4 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) PEX11 PF05648.14 CCD26147.2 - 1.7e-60 204.3 1.8 1.9e-60 204.1 1.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) TPR_2 PF07719.17 CCD26148.2 - 3.5e-23 79.8 30.8 0.00028 20.8 0.0 13.4 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_1 PF00515.28 CCD26148.2 - 3.7e-21 74.0 47.9 9.5e-06 25.2 0.0 12.9 15 0 0 15 15 14 8 Tetratricopeptide repeat TPR_19 PF14559.6 CCD26148.2 - 1.1e-17 64.3 2.5 7.1e-05 23.2 0.0 8.5 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 CCD26148.2 - 1.2e-16 60.8 11.4 0.03 14.6 0.8 10.7 8 4 2 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 CCD26148.2 - 4.5e-16 57.7 32.6 0.0037 17.4 0.2 13.5 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_14 PF13428.6 CCD26148.2 - 1.9e-15 56.2 0.0 0.032 15.1 0.0 10.7 11 2 2 13 13 11 2 Tetratricopeptide repeat TPR_16 PF13432.6 CCD26148.2 - 1e-13 51.6 0.0 0.0027 18.3 0.0 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 CCD26148.2 - 1.3e-09 38.0 20.7 0.36 11.6 0.0 11.5 14 0 0 14 14 12 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD26148.2 - 1.4e-09 38.0 12.8 0.013 15.7 0.2 7.1 5 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CCD26148.2 - 4e-09 35.8 10.1 3.9 7.7 0.0 9.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCD26148.2 - 1.1e-07 31.7 12.0 0.55 10.7 0.0 10.4 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_11 PF13414.6 CCD26148.2 - 2.7e-05 23.7 24.6 0.33 10.7 0.4 8.5 9 1 1 10 10 10 3 TPR repeat TPR_10 PF13374.6 CCD26148.2 - 0.014 15.3 16.9 0.92 9.5 0.2 9.4 12 0 0 12 12 11 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCD26148.2 - 4.3 7.5 11.7 6.8 6.9 0.0 5.6 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat DMRL_synthase PF00885.19 CCD26150.2 - 2.6e-53 179.6 0.1 3.2e-53 179.3 0.1 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Hist_deacetyl PF00850.19 CCD26151.2 - 6.8e-85 285.2 0.0 1.2e-84 284.4 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain KH_6 PF15985.5 CCD26152.2 - 1.8e-09 37.8 0.0 3.7e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 CCD26152.2 - 8.6e-08 32.0 0.0 1.7e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain E1_UFD PF09358.10 CCD26152.2 - 0.025 15.3 0.0 0.047 14.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fold domain LCM PF04072.14 CCD26153.2 - 1.1e-25 90.7 0.0 1.6e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_5 PF13854.6 CCD26153.2 - 0.00021 21.2 1.7 0.0014 18.6 0.0 3.0 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 CCD26153.2 - 0.0014 18.6 1.1 4 7.5 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CCD26153.2 - 0.079 12.6 0.1 1.6 8.4 0.0 2.8 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.6 CCD26153.2 - 0.18 12.2 0.1 0.8 10.1 0.0 2.2 2 1 0 2 2 2 0 Galactose oxidase, central domain CDC50 PF03381.15 CCD26154.2 - 6.5e-82 275.2 0.4 8.7e-82 274.8 0.4 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3098 PF11297.8 CCD26154.2 - 0.0021 17.6 0.4 0.21 11.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3098) DUF3040 PF11239.8 CCD26154.2 - 0.69 10.2 3.0 15 5.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF3185 PF11381.8 CCD26154.2 - 5.5 7.1 6.1 13 5.9 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Aminotran_3 PF00202.21 CCD26155.2 - 1.4e-129 432.4 0.1 1.7e-129 432.0 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III PucR PF07905.11 CCD26155.2 - 0.003 17.8 0.0 1.1 9.6 0.0 3.1 4 0 0 4 4 4 2 Purine catabolism regulatory protein-like family PIG-H PF10181.9 CCD26155.2 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component IF4E PF01652.18 CCD26156.2 - 4.7e-55 185.7 1.0 5.6e-55 185.5 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Hydrolase_4 PF12146.8 CCD26157.2 - 3.6e-16 59.1 0.0 9.9e-10 38.1 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCD26157.2 - 2e-09 37.5 0.0 0.0006 19.5 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CCD26157.2 - 1.6e-05 24.5 0.0 0.00011 21.8 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 CCD26157.2 - 1.9e-05 24.7 0.0 0.0049 16.8 0.0 2.4 2 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 CCD26157.2 - 6e-05 22.8 0.0 9.3e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.12 CCD26157.2 - 0.00024 20.2 0.2 0.0003 19.9 0.2 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 CCD26157.2 - 0.0034 17.0 0.0 0.022 14.3 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 CCD26157.2 - 0.0063 15.1 0.0 0.0088 14.6 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II DUF1749 PF08538.10 CCD26157.2 - 0.0093 15.1 0.0 0.021 13.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Peptidase_S15 PF02129.18 CCD26157.2 - 0.047 13.3 0.0 0.4 10.2 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Zn_ribbon_17 PF17120.5 CCD26158.2 - 1.2e-09 37.7 4.0 2.8e-09 36.5 4.0 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 CCD26158.2 - 3.5e-07 30.8 8.7 0.0013 19.5 0.3 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat zf-RING_2 PF13639.6 CCD26158.2 - 0.00051 20.3 7.6 0.0017 18.7 7.6 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CCD26158.2 - 0.00054 19.8 4.1 0.002 18.0 4.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CCD26158.2 - 0.17 12.2 13.4 0.13 12.5 10.5 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain GRA6 PF05084.13 CCD26158.2 - 0.38 10.7 3.1 0.77 9.7 3.1 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DUF3795 PF12675.7 CCD26158.2 - 1 9.8 8.2 2.9 8.4 8.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) zf-ANAPC11 PF12861.7 CCD26158.2 - 3.2 7.9 7.9 8.2 6.6 7.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CCD26158.2 - 4.9 7.1 12.3 1.2 9.0 8.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MFS_1 PF07690.16 CCD26159.2 - 3.2e-30 105.3 35.4 5.2e-25 88.1 11.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 CCD26160.2 - 4.8e-34 115.8 15.6 1.4e-06 28.9 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD26160.2 - 1.5e-19 70.1 0.9 0.038 14.3 0.0 6.4 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCD26160.2 - 3.4e-05 23.0 0.8 1.2 8.0 0.8 3.7 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CCD26160.2 - 5e-05 23.3 8.4 0.016 15.1 0.2 3.6 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A 6PF2K PF01591.18 CCD26161.2 - 1.3e-46 158.8 3.6 2.9e-46 157.6 3.6 1.6 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 CCD26161.2 - 0.00095 19.3 0.0 0.0023 18.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 CCD26161.2 - 0.0024 17.4 0.5 0.024 14.1 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 CCD26161.2 - 0.017 15.7 0.3 0.17 12.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain Ten1 PF12658.7 CCD26161.2 - 0.029 14.3 0.0 0.092 12.7 0.0 1.8 2 0 0 2 2 2 0 Telomere capping, CST complex subunit AAA_17 PF13207.6 CCD26161.2 - 0.12 12.9 0.0 0.28 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain Med7 PF05983.11 CCD26162.2 - 1.2e-36 126.6 1.2 1.5e-36 126.3 1.2 1.0 1 0 0 1 1 1 1 MED7 protein zf-rbx1 PF12678.7 CCD26163.2 - 2.7e-23 82.0 13.5 4.7e-23 81.2 13.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CCD26163.2 - 5.8e-17 61.5 10.2 7.7e-17 61.1 10.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CCD26163.2 - 1.5e-05 25.3 14.2 0.0007 19.9 14.2 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CCD26163.2 - 0.00079 19.2 3.8 0.00079 19.2 3.8 2.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCD26163.2 - 0.0031 17.3 11.7 0.031 14.1 11.7 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CCD26163.2 - 0.0049 16.6 1.3 0.0049 16.6 1.3 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CCD26163.2 - 0.33 11.1 7.1 0.49 10.6 0.5 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CCD26163.2 - 1.4 8.9 10.7 4.1 7.4 4.5 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CCD26163.2 - 1.6 8.4 15.4 0.11 12.2 5.6 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 CCD26163.2 - 1.9 8.6 9.5 5.2 7.2 9.0 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CCD26163.2 - 3.8 7.5 10.2 20 5.2 10.2 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.11 CCD26163.2 - 4.9 7.5 11.6 41 4.6 11.6 2.2 1 1 0 1 1 1 0 RING-like domain TPR_19 PF14559.6 CCD26164.2 - 1.4e-08 35.1 0.2 0.0019 18.7 0.1 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCD26164.2 - 4.2e-08 32.8 4.2 0.024 14.8 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CCD26164.2 - 6.8e-08 32.1 5.9 0.008 16.2 0.3 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CCD26164.2 - 0.00022 20.9 4.5 0.72 9.8 0.2 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCD26164.2 - 0.00024 21.4 1.7 0.12 12.7 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CCD26164.2 - 0.0012 19.5 6.2 1.7 9.6 0.1 5.3 4 2 3 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 CCD26164.2 - 0.0063 17.1 1.6 3.7 8.3 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCD26164.2 - 0.0078 16.2 2.6 1.9 8.7 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CCD26164.2 - 0.019 14.6 0.1 4.5 7.0 0.1 3.5 2 1 1 3 3 3 0 TPR repeat RPN7 PF10602.9 CCD26164.2 - 0.065 12.9 2.7 7.3 6.3 0.2 3.4 3 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_17 PF13431.6 CCD26164.2 - 0.079 13.4 4.2 0.33 11.4 0.0 4.0 5 1 0 5 5 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 CCD26164.2 - 0.15 12.3 2.3 0.63 10.2 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD26164.2 - 0.28 11.4 6.3 12 6.2 2.3 4.0 3 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 tRNA_anti-codon PF01336.25 CCD26165.2 - 1.3e-10 41.1 0.1 2.8e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.11 CCD26165.2 - 1.5e-06 28.8 0.0 3.8e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti_2 PF13742.6 CCD26165.2 - 0.023 14.9 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 CCD26165.2 - 0.032 13.9 0.4 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 HTH_IclR PF09339.10 CCD26165.2 - 0.075 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain LON_substr_bdg PF02190.16 CCD26165.2 - 0.15 11.9 0.1 0.43 10.4 0.1 1.4 1 1 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain Glyco_hydro_72 PF03198.14 CCD26166.2 - 7.4e-134 445.9 1.4 9.2e-134 445.6 1.4 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 CCD26166.2 - 0.0018 17.4 0.4 0.019 14.1 0.4 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_cc PF11790.8 CCD26166.2 - 0.0033 17.0 0.0 0.0053 16.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core UPF0220 PF05255.11 CCD26168.2 - 3.9e-72 241.2 2.6 4.4e-72 241.0 2.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Pkinase PF00069.25 CCD26169.2 - 7.6e-58 195.9 0.0 9.1e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26169.2 - 1.3e-29 103.2 0.0 1.8e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD26169.2 - 6.2e-07 29.0 0.0 9.7e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCD26169.2 - 0.00068 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CCD26169.2 - 0.003 16.9 0.1 0.0042 16.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CCD26169.2 - 0.016 14.8 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L23 PF00276.20 CCD26170.2 - 5.1e-14 52.4 3.3 3.3e-13 49.8 3.3 1.9 1 1 0 1 1 1 1 Ribosomal protein L23 Ldh_1_C PF02866.18 CCD26171.2 - 3.5e-46 157.2 0.0 5.4e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CCD26171.2 - 1.7e-41 141.6 0.2 2.6e-41 141.0 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 CCD26171.2 - 0.13 12.7 0.0 0.82 10.1 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TRM13 PF05206.14 CCD26172.2 - 2.4e-80 269.9 1.0 2.4e-80 269.9 1.0 1.9 2 0 0 2 2 2 1 Methyltransferase TRM13 zf-U11-48K PF05253.12 CCD26172.2 - 5e-11 42.3 7.4 1e-10 41.3 2.5 2.5 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.8 CCD26172.2 - 4.4e-09 35.9 3.1 4.4e-09 35.9 3.1 2.2 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein UPF0020 PF01170.18 CCD26173.2 - 7.8e-10 38.8 0.0 2.5e-08 33.8 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 CCD26173.2 - 0.0067 16.2 0.8 0.28 10.9 0.6 2.6 2 1 0 2 2 2 1 DNA methylase RRM_1 PF00076.22 CCD26174.2 - 4e-32 109.8 0.6 1.7e-15 56.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD26174.2 - 1.3e-12 47.6 0.2 2.1e-06 27.8 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif PRP38_assoc PF12871.7 CCD26174.2 - 0.033 14.8 8.1 0.13 12.9 8.1 2.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Glyco_H_20C_C PF18088.1 CCD26174.2 - 0.053 13.4 0.2 0.1 12.4 0.2 1.4 1 0 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain DUF4199 PF13858.6 CCD26174.2 - 0.62 10.5 1.8 1.3 9.4 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Nramp PF01566.18 CCD26175.2 - 1.4e-86 290.7 19.7 1.4e-86 290.7 19.7 2.2 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Ribosomal_S19e PF01090.19 CCD26176.2 - 1.1e-53 180.6 0.1 1.3e-53 180.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L18 PF17135.4 CCD26177.2 - 2.3e-87 291.3 2.1 2.5e-87 291.1 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CCD26177.2 - 0.0019 18.9 0.2 0.0048 17.6 0.2 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A IL15 PF02372.15 CCD26178.2 - 0.055 13.5 1.4 0.43 10.6 0.1 2.8 2 0 0 2 2 2 0 Interleukin 15 GCR1_C PF12550.8 CCD26179.2 - 6.3e-23 80.9 0.2 1.3e-22 79.8 0.2 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes NTP_transf_2 PF01909.23 CCD26180.2 - 6e-17 61.7 0.7 1.7e-16 60.3 0.0 2.2 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CCD26180.2 - 7e-14 51.8 0.0 1.9e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 CCD26180.2 - 0.0011 18.9 0.1 0.0034 17.4 0.1 1.8 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase RF-1 PF00472.20 CCD26181.2 - 1.1e-16 60.8 0.0 1.7e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 CCD26181.2 - 0.02 15.3 0.4 0.047 14.1 0.3 1.6 1 1 1 2 2 2 0 Mitochondrial ribosomal subunit protein zinc_ribbon_11 PF11682.8 CCD26181.2 - 0.054 13.5 0.1 0.15 12.1 0.1 1.8 1 1 0 1 1 1 0 Probable zinc-ribbon RabGAP-TBC PF00566.18 CCD26182.2 - 6.1e-42 143.7 5.9 1.8e-30 106.2 0.4 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Get5_bdg PF16843.5 CCD26183.2 - 5.2e-27 93.1 2.5 1.2e-26 91.9 0.6 2.1 2 0 0 2 2 2 1 Binding domain to Get4 on Get5, Golgi to ER traffic protein Get5_C PF18514.1 CCD26183.2 - 3.4e-20 71.5 1.8 1.4e-19 69.5 0.3 2.5 2 0 0 2 2 2 1 Get5 C-terminal domain ubiquitin PF00240.23 CCD26183.2 - 0.00043 20.0 0.6 0.00074 19.2 0.2 1.6 2 0 0 2 2 2 1 Ubiquitin family Homeodomain PF00046.29 CCD26184.1 - 9.5e-14 51.0 1.0 1.6e-13 50.3 1.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CCD26184.1 - 1.3e-05 25.0 0.1 2.1e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 CCD26184.1 - 0.062 12.8 0.3 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Sir1 PF11603.8 CCD26185.1 - 1.1e-31 109.8 1.7 1.1e-27 96.9 0.0 2.9 3 0 0 3 3 3 2 Regulatory protein Sir1 Reg_prop PF07494.11 CCD26185.1 - 0.16 12.2 0.4 0.71 10.3 0.1 2.2 2 0 0 2 2 2 0 Two component regulator propeller DHO_dh PF01180.21 CCD26186.1 - 4.3e-92 308.5 0.0 4.8e-92 308.3 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CCD26186.1 - 8.4e-05 21.7 0.0 0.0048 16.0 0.0 2.1 2 0 0 2 2 2 2 FMN-dependent dehydrogenase SBF PF01758.16 CCD26187.1 - 4.7e-51 173.2 14.2 4.7e-51 173.2 14.2 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family MFS_1 PF07690.16 CCD26188.1 - 8.2e-11 41.4 41.7 4.5e-10 39.0 40.7 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CCD26188.1 - 1.3e-05 23.9 24.1 0.00055 18.5 24.1 2.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CCD26188.1 - 0.00071 18.5 8.0 0.00071 18.5 8.0 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter SET PF00856.28 CCD26189.1 - 3e-07 31.0 0.1 1.1e-06 29.2 0.0 2.0 2 0 0 2 2 2 1 SET domain RTTN_N PF14726.6 CCD26189.1 - 0.47 11.3 2.9 22 5.9 0.1 2.9 2 1 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Cofilin_ADF PF00241.20 CCD26190.1 - 2.6e-41 140.2 0.5 2.9e-41 140.1 0.5 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CBM_4_9 PF02018.17 CCD26190.1 - 0.036 14.3 0.1 0.062 13.6 0.1 1.4 2 0 0 2 2 2 0 Carbohydrate binding domain AA_permease_2 PF13520.6 CCD26192.1 - 2.9e-50 171.4 40.8 3.7e-50 171.0 40.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCD26192.1 - 1.8e-08 33.5 36.0 2.4e-08 33.0 36.0 1.1 1 0 0 1 1 1 1 Amino acid permease ABC_membrane PF00664.23 CCD26193.1 - 2.5e-57 194.6 31.0 1.4e-35 123.3 14.5 3.7 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 CCD26193.1 - 1.1e-54 184.7 0.0 3.1e-30 105.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CCD26193.1 - 6.8e-10 38.8 4.3 0.00024 20.6 1.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CCD26193.1 - 1.3e-08 34.9 0.1 0.00036 20.5 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 CCD26193.1 - 1.1e-07 32.0 6.6 0.0057 16.5 0.1 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CCD26193.1 - 4.5e-07 29.9 0.4 0.0023 18.0 0.2 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 CCD26193.1 - 4.9e-07 30.5 11.4 0.00011 22.8 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 CCD26193.1 - 6.9e-07 28.9 0.1 0.049 13.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CCD26193.1 - 3.2e-05 24.2 0.0 0.44 10.8 0.1 3.3 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 CCD26193.1 - 6.2e-05 22.2 0.0 0.029 13.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Dynamin_N PF00350.23 CCD26193.1 - 7.7e-05 22.8 3.0 0.081 13.0 0.2 3.4 3 1 0 3 3 3 2 Dynamin family AAA_16 PF13191.6 CCD26193.1 - 0.00013 22.4 0.5 0.59 10.5 0.0 3.1 3 1 0 3 3 2 2 AAA ATPase domain AAA_15 PF13175.6 CCD26193.1 - 0.00021 21.1 1.4 0.0082 15.9 0.4 3.8 5 0 0 5 5 4 2 AAA ATPase domain Zeta_toxin PF06414.12 CCD26193.1 - 0.00051 19.4 0.0 1.2 8.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_24 PF13479.6 CCD26193.1 - 0.00071 19.3 0.0 0.05 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CCD26193.1 - 0.0011 19.1 3.0 1.1 9.3 0.1 2.9 3 0 0 3 3 2 2 Helicase HerA, central domain AAA_7 PF12775.7 CCD26193.1 - 0.0029 17.1 0.1 0.6 9.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 CCD26193.1 - 0.0031 18.0 1.6 9.3 6.7 0.1 4.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 CCD26193.1 - 0.0052 16.6 0.0 2.1 8.1 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 CCD26193.1 - 0.0067 16.2 0.0 2.5 7.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 CCD26193.1 - 0.012 15.6 0.0 12 5.9 0.0 3.5 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Adeno_IVa2 PF02456.15 CCD26193.1 - 0.016 14.0 0.0 0.098 11.4 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_14 PF13173.6 CCD26193.1 - 0.017 15.2 0.2 6.3 6.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 CCD26193.1 - 0.018 14.7 0.2 4.8 6.9 0.0 3.5 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_25 PF13481.6 CCD26193.1 - 0.026 14.1 0.0 0.76 9.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain Guanylate_kin PF00625.21 CCD26193.1 - 0.035 13.8 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Guanylate kinase DUF815 PF05673.13 CCD26193.1 - 0.053 12.7 0.0 4.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 CCD26193.1 - 0.055 12.8 0.1 11 5.3 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 CCD26193.1 - 0.061 12.9 0.1 2.8 7.5 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ERp29_N PF07912.13 CCD26193.1 - 0.067 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 ERp29, N-terminal domain AAA_18 PF13238.6 CCD26193.1 - 0.091 13.3 0.0 30 5.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 CCD26193.1 - 0.11 12.1 0.0 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CCD26193.1 - 0.16 12.2 1.4 22 5.3 0.1 3.2 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 CCD26193.1 - 0.16 12.2 0.0 33 4.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.22 CCD26194.1 - 1e-16 60.5 0.3 2.5e-09 36.8 0.1 3.7 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD26194.1 - 0.00026 21.0 0.0 0.00095 19.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif RRM_Rrp7 PF17799.1 CCD26194.1 - 0.026 14.3 0.0 7.9 6.3 0.0 2.4 2 1 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Caprin-1_C PF12287.8 CCD26194.1 - 4.1 7.5 8.6 8.4 6.4 8.6 1.5 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Ribosomal_L7Ae PF01248.26 CCD26195.1 - 3.6e-23 81.1 0.2 6.2e-23 80.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CCD26195.1 - 0.00069 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 FGGY_C PF02782.16 CCD26196.1 - 2.1e-67 226.7 0.1 9.9e-67 224.5 0.1 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CCD26196.1 - 2.6e-48 164.7 0.0 8.1e-41 140.2 0.0 2.9 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain HTH_24 PF13412.6 CCD26196.1 - 0.11 12.1 0.2 6 6.5 0.0 3.1 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding MIP PF00230.20 CCD26197.1 - 4.5e-72 242.4 6.2 6e-72 242.0 6.2 1.2 1 0 0 1 1 1 1 Major intrinsic protein V-SNARE_C PF12352.8 CCD26198.1 - 5.9e-15 55.3 4.6 5.9e-15 55.3 4.6 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Syntaxin-6_N PF09177.11 CCD26198.1 - 0.01 16.3 3.4 0.01 16.3 3.4 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal RseA_N PF03872.13 CCD26198.1 - 0.021 15.3 0.4 0.049 14.1 0.4 1.7 1 0 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain U3snoRNP10 PF12397.8 CCD26198.1 - 0.055 13.8 2.3 1.2 9.5 0.1 2.5 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 DUF349 PF03993.12 CCD26198.1 - 0.14 12.5 5.4 0.075 13.3 2.4 2.1 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) Ac76 PF05814.11 CCD26198.1 - 0.83 9.7 5.0 0.62 10.1 0.4 2.5 2 0 0 2 2 2 0 Orf76 (Ac76) DUF3552 PF12072.8 CCD26198.1 - 2.4 7.5 13.7 2.8 7.3 3.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF4200 PF13863.6 CCD26198.1 - 4.1 7.8 15.5 5 7.6 4.6 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Atg14 PF10186.9 CCD26198.1 - 5 6.1 17.6 21 4.1 17.6 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PMC2NT PF08066.12 CCD26198.1 - 5.3 7.8 8.1 23 5.8 0.2 2.7 2 1 1 3 3 3 0 PMC2NT (NUC016) domain Fer2_3 PF13085.6 CCD26199.1 - 1.5e-33 115.1 0.1 2.8e-33 114.2 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CCD26199.1 - 3e-09 37.3 7.8 3e-09 37.3 7.8 2.2 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CCD26199.1 - 4.5e-08 33.4 8.3 4.5e-08 33.4 8.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CCD26199.1 - 2e-07 31.0 4.1 2e-07 31.0 4.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CCD26199.1 - 0.00037 20.4 3.4 0.0054 16.7 1.0 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 CCD26199.1 - 0.0019 18.8 6.1 0.0019 18.8 6.1 2.3 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 CCD26199.1 - 0.012 15.8 0.6 0.81 9.9 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 CCD26199.1 - 0.013 15.6 7.7 0.013 15.6 7.7 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain Ecm29 PF13001.7 CCD26200.1 - 3.2e-140 468.1 13.3 3.2e-140 468.1 13.3 4.1 5 0 0 5 5 5 2 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 CCD26200.1 - 1.1e-08 35.5 4.4 0.00032 21.2 0.0 6.2 6 1 1 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CCD26200.1 - 2.6e-08 33.4 7.8 0.14 12.5 0.0 7.6 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 CCD26200.1 - 0.0009 19.7 0.1 25 5.5 0.0 5.7 6 0 0 6 6 6 1 HEAT-like repeat TFCD_C PF12612.8 CCD26200.1 - 0.024 14.5 2.7 0.27 11.1 0.0 4.3 5 0 0 5 5 5 0 Tubulin folding cofactor D C terminal NopRA1 PF16201.5 CCD26200.1 - 0.12 12.0 4.9 1.6 8.2 1.1 4.0 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 ubiquitin PF00240.23 CCD26201.1 - 8.6e-35 118.3 0.6 9.4e-35 118.2 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CCD26201.1 - 5.4e-17 61.4 0.7 6e-17 61.3 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CCD26201.1 - 4.1e-06 27.2 0.2 1.7e-05 25.2 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CCD26201.1 - 0.0011 19.3 0.0 0.0012 19.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CCD26201.1 - 0.0013 18.6 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 CCD26201.1 - 0.0014 18.7 0.3 1.4 9.1 0.1 2.0 2 0 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CCD26201.1 - 0.0024 18.0 0.1 0.0052 16.9 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CCD26201.1 - 0.017 15.7 0.1 0.019 15.5 0.1 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CCD26201.1 - 0.018 14.9 0.0 0.021 14.7 0.0 1.1 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain ENTH PF01417.20 CCD26202.1 - 1.3e-28 99.6 4.7 1.9e-28 99.0 4.7 1.3 1 0 0 1 1 1 1 ENTH domain VHS PF00790.19 CCD26202.1 - 0.031 14.1 0.6 0.44 10.4 0.6 2.4 1 1 0 1 1 1 0 VHS domain zf-C2H2 PF00096.26 CCD26204.1 - 1.9e-06 28.0 21.7 2.5e-05 24.5 3.6 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCD26204.1 - 7.4e-05 23.0 3.1 7.4e-05 23.0 3.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCD26204.1 - 0.0011 19.6 2.5 0.0011 19.6 2.5 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCD26204.1 - 0.0045 16.9 2.6 0.0045 16.9 2.6 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCD26204.1 - 0.0068 16.7 1.0 0.023 15.0 1.0 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCD26204.1 - 0.0075 16.6 0.7 0.029 14.8 0.7 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2HE PF16278.5 CCD26204.1 - 0.032 14.7 6.5 0.12 12.8 6.5 2.1 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger TFIIA PF03153.13 CCD26205.1 - 0.023 14.7 59.8 0.035 14.1 42.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 CCD26205.1 - 0.27 11.2 36.1 1.5 8.8 4.1 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF501 PF04417.12 CCD26205.1 - 1.4 8.7 0.0 1.4 8.7 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF501) SRP-alpha_N PF04086.13 CCD26205.1 - 1.7 8.5 36.4 0.37 10.7 28.1 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal AGH PF17558.2 CCD26205.1 - 2 8.6 4.4 0.46 10.6 0.5 1.9 2 0 0 2 2 2 0 Androgenic gland hormone Phosphodiest PF01663.22 CCD26206.1 - 6.7e-13 48.9 0.4 1.2e-12 48.1 0.4 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CCD26206.1 - 0.039 13.3 1.6 0.043 13.2 0.5 1.5 2 0 0 2 2 2 0 Metalloenzyme superfamily Sulfatase PF00884.23 CCD26206.1 - 0.065 12.6 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Sulfatase ACT_3 PF10000.9 CCD26206.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 ACT domain Creatinase_N_2 PF16189.5 CCD26207.1 - 2.4e-42 144.8 0.9 1.8e-40 138.7 0.1 2.7 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CCD26207.1 - 1.3e-39 136.1 0.0 1.8e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 CCD26207.1 - 8.2e-21 73.8 3.3 1.3e-20 73.2 1.9 2.2 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CCD26207.1 - 3.7e-10 40.6 0.0 1.2e-09 38.9 0.0 1.8 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain NPR3 PF03666.13 CCD26208.1 - 1.1e-172 575.1 4.3 1.1e-172 575.1 4.3 3.6 3 1 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 HSP70 PF00012.20 CCD26209.1 - 1.2e-261 869.2 8.9 1.4e-261 869.0 8.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCD26209.1 - 1.7e-17 63.3 0.1 5.1e-16 58.4 0.0 2.5 3 0 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.16 CCD26209.1 - 0.0031 17.2 0.0 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 CCD26209.1 - 0.0092 15.0 0.6 0.13 11.3 0.1 2.6 2 1 1 3 3 3 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 CCD26209.1 - 0.12 11.6 0.1 0.12 11.6 0.1 2.4 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase PMBR PF09373.10 CCD26209.1 - 1.5 9.1 0.0 1.5 9.1 0.0 2.8 4 0 0 4 4 4 0 Pseudomurein-binding repeat TMCO5 PF14992.6 CCD26209.1 - 1.9 8.0 8.3 3.7 7.1 8.3 1.4 1 0 0 1 1 1 0 TMCO5 family Septin PF00735.18 CCD26210.1 - 7.3e-103 343.7 9.4 7.3e-103 343.7 9.4 3.0 2 1 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CCD26210.1 - 2.9e-05 24.1 0.1 2.9e-05 24.1 0.1 2.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCD26210.1 - 4.8e-05 23.0 0.5 4.8e-05 23.0 0.5 2.9 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CCD26210.1 - 0.00015 22.2 0.1 0.0015 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 CCD26210.1 - 0.00055 20.1 0.1 0.0018 18.5 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 CCD26210.1 - 0.0015 18.8 0.4 0.019 15.3 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_23 PF13476.6 CCD26210.1 - 0.0026 18.3 4.7 0.0026 18.3 4.7 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CCD26210.1 - 0.0074 16.2 2.5 0.0074 16.2 2.5 3.5 3 1 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 CCD26210.1 - 0.019 15.5 0.3 0.019 15.5 0.3 2.8 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 CCD26210.1 - 0.025 14.1 1.9 0.034 13.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3150 PF11348.8 CCD26210.1 - 0.097 11.9 6.8 0.16 11.2 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) AAA_24 PF13479.6 CCD26210.1 - 0.18 11.5 2.8 0.21 11.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CCD26210.1 - 0.75 10.2 0.0 0.75 10.2 0.0 2.7 3 0 0 3 3 2 0 RNA helicase DUF3987 PF13148.6 CCD26210.1 - 1.1 8.2 7.5 8.6 5.3 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3987) SepSecS PF05889.13 CCD26210.1 - 1.8 7.2 6.2 2.2 6.9 4.6 2.0 2 1 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS GIT_SHD PF08518.11 CCD26211.1 - 3.2e-20 71.4 10.9 2e-10 40.1 0.3 2.9 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT Cnn_1N PF07989.11 CCD26211.1 - 0.034 14.3 8.5 0.31 11.2 8.5 2.7 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 CCD26211.1 - 0.57 10.0 6.0 1.4 8.7 4.9 2.4 1 1 1 2 2 2 0 Septum formation initiator Ribonucleas_3_3 PF14622.6 CCD26212.1 - 4.1e-22 78.7 0.0 8.2e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 CCD26212.1 - 6.6e-09 36.3 0.0 1.8e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease III domain SH3_1 PF00018.28 CCD26214.1 - 1.2e-08 34.4 2.6 1.9e-07 30.6 0.1 3.1 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.6 CCD26214.1 - 1.5e-07 31.1 0.0 0.0001 22.1 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CCD26214.1 - 6e-07 29.1 1.5 6.8e-06 25.7 1.5 2.3 1 1 0 1 1 1 1 Variant SH3 domain RasGEF PF00617.19 CCD26215.1 - 4.4e-56 189.9 0.2 4.4e-56 189.9 0.2 3.9 4 0 0 4 4 4 1 RasGEF domain RasGEF_N PF00618.20 CCD26215.1 - 1.5e-18 67.0 0.1 1.5e-18 67.0 0.1 6.3 6 2 1 7 7 7 1 RasGEF N-terminal motif Gtr1_RagA PF04670.12 CCD26216.1 - 1.4e-67 227.4 1.1 1.8e-67 227.1 1.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 CCD26216.1 - 0.00072 19.6 0.0 0.0019 18.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Arf PF00025.21 CCD26216.1 - 0.0076 15.7 0.1 0.034 13.6 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF815 PF05673.13 CCD26216.1 - 0.01 15.0 0.0 0.039 13.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SRPRB PF09439.10 CCD26216.1 - 0.068 12.6 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MIF4G PF02854.19 CCD26217.1 - 1.4e-50 171.9 0.3 2.2e-50 171.2 0.3 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 CCD26217.1 - 1.1e-26 92.8 1.7 1.8e-26 92.1 0.2 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 DUF1484 PF07363.11 CCD26217.1 - 1.8 9.6 0.0 1.8 9.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1484) Glyco_tran_28_C PF04101.16 CCD26218.1 - 5.9e-23 81.7 0.0 2.3e-18 66.7 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain DUF2046 PF09755.9 CCD26219.1 - 6.2e-05 22.4 1.4 7.2e-05 22.2 1.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) FXMRP1_C_core PF12235.8 CCD26219.1 - 0.00058 20.5 1.4 0.001 19.7 1.4 1.6 1 1 0 1 1 1 1 Fragile X-related 1 protein core C terminal SYCE1 PF15233.6 CCD26219.1 - 0.0067 16.5 3.4 0.0096 16.0 3.4 1.3 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 Herpes_UL6 PF01763.16 CCD26219.1 - 0.044 12.3 1.7 0.046 12.2 1.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like BROMI PF14961.6 CCD26219.1 - 0.24 8.8 4.1 0.27 8.6 4.1 1.0 1 0 0 1 1 1 0 Broad-minded protein Spt4 PF06093.13 CCD26220.1 - 0.49 10.5 2.2 12 6.1 0.3 2.7 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger PEMT PF04191.13 CCD26221.1 - 3.6e-53 178.4 19.8 2.1e-31 108.5 2.3 3.9 3 1 0 3 3 3 2 Phospholipid methyltransferase HECW_N PF16562.5 CCD26221.1 - 0.0016 18.2 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 CCD26221.1 - 0.031 14.8 0.2 0.24 12.0 0.2 2.5 1 1 0 1 1 1 0 SKICH domain CSTF2_hinge PF14327.6 CCD26222.1 - 5.5e-23 81.2 2.4 5.5e-23 81.2 2.4 3.3 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 DUF5339 PF17274.2 CCD26222.1 - 0.0078 17.0 1.3 0.0078 17.0 1.3 3.4 4 0 0 4 4 4 1 Family of unknown function (DUF5339) TFIIA PF03153.13 CCD26222.1 - 6.4 6.7 44.9 7 6.5 3.7 2.1 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit His_Phos_1 PF00300.22 CCD26223.1 - 2.6e-09 37.0 0.1 0.00085 19.1 0.0 3.2 2 2 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) SprT-like PF10263.9 CCD26223.1 - 0.0073 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 SprT-like family PALP PF00291.25 CCD26224.1 - 8.5e-62 209.2 0.0 1e-61 208.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 CCD26224.1 - 2.2e-18 66.4 0.1 1e-09 38.7 0.1 2.8 2 0 0 2 2 2 2 CBS domain DUF1279 PF06916.13 CCD26226.1 - 1.1e-23 83.5 0.0 1.9e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Golgin_A5 PF09787.9 CCD26226.1 - 0.044 13.2 0.2 0.061 12.8 0.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Ribosomal_L24e PF01246.20 CCD26227.1 - 6.6e-30 103.1 0.2 6.6e-30 103.1 0.2 2.1 2 1 0 2 2 2 1 Ribosomal protein L24e UNC-79 PF14776.6 CCD26227.1 - 0.2 10.4 0.6 0.24 10.1 0.6 1.0 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 DUF2838 PF10998.8 CCD26228.1 - 1.2e-41 141.4 13.6 1.2e-41 141.4 13.6 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2838) Bcr-Abl_Oligo PF09036.10 CCD26228.1 - 1.8 8.6 6.5 0.18 11.8 0.3 2.3 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain DUF4131 PF13567.6 CCD26228.1 - 3.7 7.2 6.2 4 7.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PPR_2 PF13041.6 CCD26229.1 - 1.5e-12 47.5 0.4 6.5e-07 29.5 0.0 3.0 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.6 CCD26229.1 - 1.7e-11 44.0 0.4 6.7e-07 29.3 0.1 3.0 1 1 1 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 CCD26229.1 - 2.6e-05 24.1 0.7 0.26 11.6 0.0 3.8 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 CCD26229.1 - 0.019 14.4 0.0 0.06 12.7 0.0 1.8 1 1 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CCD26229.1 - 0.031 14.0 0.0 6.8 6.5 0.0 2.7 2 0 0 2 2 2 0 PPR repeat Cgr1 PF03879.14 CCD26230.1 - 2e-33 115.0 34.9 2.3e-33 114.8 34.9 1.0 1 0 0 1 1 1 1 Cgr1 family DUF2048 PF09752.9 CCD26230.1 - 0.044 12.9 4.5 0.05 12.7 4.5 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 UPF0242 PF06785.11 CCD26230.1 - 4.3 7.4 16.4 5.5 7.0 16.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Rrn6 PF10214.9 CCD26231.1 - 1.2e-146 490.5 17.7 2.3e-146 489.6 17.7 1.5 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Trp_syntA PF00290.20 CCD26232.1 - 1.3e-98 328.9 0.6 1.9e-98 328.4 0.6 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 CCD26232.1 - 5e-49 167.3 2.5 6.6e-49 166.9 0.9 1.9 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme BtpA PF03437.15 CCD26232.1 - 0.035 13.5 1.0 0.063 12.7 0.1 1.9 2 0 0 2 2 2 0 BtpA family PcrB PF01884.17 CCD26232.1 - 0.053 13.0 0.1 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 PcrB family Ribosomal_L3 PF00297.22 CCD26233.1 - 4.9e-190 631.2 11.4 5.6e-190 631.0 11.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Pkinase PF00069.25 CCD26235.1 - 9.1e-55 185.8 0.2 2.3e-54 184.5 0.2 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26235.1 - 4.6e-17 62.2 0.0 6.4e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCD26235.1 - 4.2e-07 30.2 0.0 1.9e-06 28.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CCD26235.1 - 0.0087 15.7 0.1 0.019 14.6 0.1 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CCD26235.1 - 0.03 13.1 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CCD26235.1 - 0.1 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TP_methylase PF00590.20 CCD26236.1 - 2.5e-39 135.4 0.0 3.4e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.6 CCD26236.1 - 1e-05 24.9 0.1 2.7e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.6 CCD26236.1 - 4.6e-05 23.8 0.0 0.00012 22.4 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 CCD26236.1 - 0.004 16.8 0.2 0.36 10.5 0.1 2.5 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Hydrolase_like PF13242.6 CCD26237.1 - 2.1e-26 91.8 0.0 4.2e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 CCD26237.1 - 7.9e-24 83.7 0.0 1.4e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CCD26237.1 - 0.00075 19.6 0.0 0.05 13.7 0.0 2.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCD26237.1 - 0.015 15.6 0.1 4.4 7.5 0.1 3.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase CIAPIN1 PF05093.13 CCD26238.1 - 1.8e-37 127.9 4.6 1.8e-37 127.9 4.6 2.3 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 CCD26238.1 - 1.6e-33 115.8 0.1 2.5e-33 115.1 0.1 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus DUF4264 PF14084.6 CCD26238.1 - 0.045 13.4 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) zf-CSL PF05207.13 CCD26238.1 - 2.2 8.1 7.5 14 5.5 6.4 2.6 1 1 1 2 2 2 0 CSL zinc finger Nop16 PF09420.10 CCD26238.1 - 7.2 6.6 8.6 16 5.5 8.6 1.6 1 1 0 1 1 1 0 Ribosome biogenesis protein Nop16 Flavoprotein PF02441.19 CCD26239.1 - 2e-50 170.6 0.1 3.7e-50 169.8 0.1 1.5 1 0 0 1 1 1 1 Flavoprotein Nop14 PF04147.12 CCD26239.1 - 2.8 6.0 48.9 0.091 11.0 42.6 1.7 2 0 0 2 2 2 0 Nop14-like family Trm112p PF03966.16 CCD26240.1 - 6.1e-20 71.6 0.1 8.5e-20 71.1 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein PIN_6 PF17146.4 CCD26241.1 - 8.6e-32 109.5 0.0 2.1e-31 108.3 0.0 1.7 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 CCD26241.1 - 1.6e-25 89.0 0.8 4.6e-25 87.6 0.8 1.8 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.10 CCD26241.1 - 0.086 13.0 0.4 0.18 11.9 0.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain SGS PF05002.15 CCD26242.1 - 1.3e-30 105.3 4.2 1.7e-30 105.0 1.8 2.5 2 0 0 2 2 2 1 SGS domain CS PF04969.16 CCD26242.1 - 4.4e-11 43.7 0.3 8.5e-11 42.7 0.3 1.5 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 CCD26242.1 - 0.012 15.7 6.1 7 7.0 0.6 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CCD26242.1 - 0.062 13.5 6.3 1.7 9.0 1.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CCD26242.1 - 0.19 12.3 2.1 0.53 10.8 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4718 PF15842.5 CCD26243.1 - 0.033 14.0 0.3 0.046 13.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Peptidase_M73 PF12389.8 CCD26244.1 - 0.0046 16.8 0.4 0.0055 16.6 0.4 1.2 1 0 0 1 1 1 1 Camelysin metallo-endopeptidase TRAPP PF04051.16 CCD26245.1 - 3.7e-31 107.8 0.0 5.4e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Dsl1_N PF11988.8 CCD26245.1 - 0.0021 17.1 0.5 0.064 12.2 0.0 2.1 2 0 0 2 2 2 2 Retrograde transport protein Dsl1 N terminal Acyltransferase PF01553.21 CCD26246.1 - 2.1e-07 30.6 0.0 3.5e-06 26.7 0.0 2.6 2 1 0 2 2 2 1 Acyltransferase STD1 PF17235.2 CCD26248.1 - 1.1e-70 237.5 4.1 1.1e-70 237.5 4.1 2.4 3 0 0 3 3 3 1 STD1/MTH1 Orthopox_F14 PF06076.12 CCD26248.1 - 0.024 14.9 0.2 0.27 11.5 0.0 2.5 3 0 0 3 3 3 0 Orthopoxvirus F14 protein DUF4407 PF14362.6 CCD26248.1 - 0.23 10.8 8.0 0.089 12.1 4.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pmp3 PF01679.17 CCD26249.1 - 1.2e-16 60.6 8.4 1.3e-16 60.5 8.4 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BTP PF05232.12 CCD26249.1 - 0.03 14.4 3.9 0.036 14.1 3.9 1.1 1 0 0 1 1 1 0 Chlorhexidine efflux transporter DUF4191 PF13829.6 CCD26249.1 - 2.1 7.7 3.7 2.2 7.6 3.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) BTB_2 PF02214.22 CCD26252.1 - 0.023 15.0 0.4 1.1 9.6 0.1 2.9 3 0 0 3 3 3 0 BTB/POZ domain E1-E2_ATPase PF00122.20 CCD26254.1 - 3.9e-45 153.6 0.1 3.9e-45 153.6 0.1 2.5 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 CCD26254.1 - 8.2e-30 104.7 0.0 2.3e-29 103.2 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CCD26254.1 - 2.8e-26 91.7 12.7 2.7e-13 50.2 2.8 3.5 3 0 0 3 3 3 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 CCD26254.1 - 4e-05 23.5 7.6 0.00027 20.8 0.1 4.1 3 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase Spore_YhcN_YlaJ PF09580.10 CCD26254.1 - 0.054 13.6 2.4 4.6 7.3 0.4 2.5 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) MTHFR_C PF12225.8 CCD26254.1 - 0.22 11.2 8.8 0.75 9.5 1.1 2.6 2 0 0 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal DUF1656 PF07869.12 CCD26254.1 - 2.8 8.0 5.8 1.6 8.8 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) tRNA-synt_1b PF00579.25 CCD26255.1 - 2.5e-74 250.3 0.1 3.1e-74 249.9 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Securin PF04856.13 CCD26255.1 - 0.046 13.7 0.5 0.066 13.2 0.5 1.3 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor WD40 PF00400.32 CCD26256.1 - 2.2e-35 120.1 21.2 5e-07 30.3 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD26256.1 - 1.4e-12 47.7 8.8 0.002 18.4 0.1 6.0 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CCD26256.1 - 0.035 13.1 4.8 0.67 8.9 0.6 3.0 2 1 1 3 3 3 0 Coatomer WD associated region SH3_9 PF14604.6 CCD26256.1 - 0.042 13.7 0.5 0.27 11.1 0.3 2.4 2 0 0 2 2 2 0 Variant SH3 domain zf-C3HC4_3 PF13920.6 CCD26257.1 - 3.5e-08 33.2 8.2 3.5e-08 33.2 8.2 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCD26257.1 - 0.003 17.4 8.5 0.003 17.4 8.5 3.7 5 0 0 5 5 5 1 Prokaryotic RING finger family 4 Peptidase_S76 PF13611.6 CCD26257.1 - 0.022 15.1 0.2 0.082 13.2 0.2 2.0 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 Mur_ligase_C PF02875.21 CCD26257.1 - 0.042 14.1 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Ribosomal_S25 PF03297.15 CCD26257.1 - 6 7.1 13.0 47 4.3 0.0 2.9 2 0 0 2 2 2 0 S25 ribosomal protein Pex2_Pex12 PF04757.14 CCD26258.1 - 4.4e-33 114.8 3.8 7.7e-33 114.0 3.8 1.4 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 CCD26258.1 - 3.4e-08 33.7 17.1 5.5e-08 33.0 17.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CCD26258.1 - 1.9e-07 30.8 16.5 3e-07 30.2 16.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCD26258.1 - 2.6e-05 24.0 15.9 4.6e-05 23.2 15.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCD26258.1 - 4e-05 23.4 14.6 7.1e-05 22.6 14.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCD26258.1 - 7.3e-05 22.6 17.0 0.00013 21.8 17.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CCD26258.1 - 8.6e-05 22.5 9.0 8.6e-05 22.5 9.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CCD26258.1 - 0.00047 20.1 12.1 0.001 19.0 12.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CCD26258.1 - 0.0008 19.6 12.3 0.0017 18.6 12.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CCD26258.1 - 0.0074 16.4 15.6 0.013 15.6 15.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CCD26258.1 - 1.2 9.0 10.5 2.8 7.9 10.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein IBR PF01485.21 CCD26258.1 - 10 6.5 13.7 12 6.2 12.2 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Ank_2 PF12796.7 CCD26259.1 - 4.1e-33 113.8 0.2 1.6e-15 57.5 0.1 3.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) DHHC PF01529.20 CCD26259.1 - 1.1e-25 90.3 5.6 1.1e-25 90.3 5.6 3.1 3 1 1 4 4 4 1 DHHC palmitoyltransferase Ank_4 PF13637.6 CCD26259.1 - 2.7e-25 88.4 0.1 2.3e-07 31.2 0.2 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CCD26259.1 - 4.2e-25 87.5 0.9 1.1e-08 35.1 0.4 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CCD26259.1 - 1.4e-24 85.3 2.4 1.7e-05 25.0 0.0 7.0 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.6 CCD26259.1 - 3.8e-24 82.1 0.8 0.00015 21.9 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat VCH_CASS14 PF18315.1 CCD26259.1 - 0.0059 16.6 0.0 0.97 9.5 0.0 2.6 2 1 0 2 2 2 1 Integron cassette protein VCH_CASS1 chain XPG_N PF00752.17 CCD26260.1 - 4.2e-24 84.9 0.0 1e-23 83.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CCD26260.1 - 1.3e-20 73.5 0.0 4.4e-20 71.8 0.0 2.0 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CCD26260.1 - 0.0021 18.6 0.0 0.0073 16.9 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 CCD26260.1 - 0.052 13.6 0.0 4.3 7.5 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif Fasciclin PF02469.22 CCD26261.1 - 0.0023 18.1 0.0 0.0047 17.1 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain Cellulase PF00150.18 CCD26262.1 - 1.4e-14 54.2 17.1 8.3e-14 51.7 17.1 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Apc13p PF05839.11 CCD26263.1 - 8.6e-05 22.7 3.3 0.00013 22.1 3.3 1.4 1 1 0 1 1 1 1 Apc13p protein AAA_2 PF07724.14 CCD26264.1 - 6.7e-49 166.3 0.1 1.2e-46 158.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CCD26264.1 - 1.6e-35 121.2 0.8 1.6e-35 121.2 0.8 2.9 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 CCD26264.1 - 1.6e-25 89.0 0.1 5.5e-25 87.2 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CCD26264.1 - 4e-21 75.8 0.2 4.4e-11 43.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CCD26264.1 - 5.4e-14 52.4 0.2 8.1e-10 38.8 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCD26264.1 - 1.4e-11 45.1 2.0 0.00045 20.6 0.3 4.4 2 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CCD26264.1 - 4.8e-07 30.1 0.4 0.028 14.7 0.1 3.7 2 2 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CCD26264.1 - 7.8e-07 29.0 0.1 0.0089 15.8 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein TniB PF05621.11 CCD26264.1 - 9.6e-07 28.4 0.1 0.0005 19.5 0.0 3.8 3 1 0 3 3 3 1 Bacterial TniB protein Sigma54_activat PF00158.26 CCD26264.1 - 1.5e-06 28.0 0.1 5.8e-05 22.9 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 CCD26264.1 - 8.2e-06 25.9 0.4 0.018 15.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 CCD26264.1 - 1.2e-05 25.4 8.7 0.067 13.1 0.1 4.6 3 3 2 5 5 4 2 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CCD26264.1 - 5.5e-05 22.8 0.0 0.08 12.4 0.0 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region NACHT PF05729.12 CCD26264.1 - 8.9e-05 22.5 0.0 0.088 12.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 CCD26264.1 - 0.0001 22.3 0.8 0.04 13.8 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 CCD26264.1 - 0.0002 21.9 2.5 0.17 12.4 0.0 3.4 3 1 0 3 3 3 1 ABC transporter AAA_29 PF13555.6 CCD26264.1 - 0.00022 20.9 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain TsaE PF02367.17 CCD26264.1 - 0.001 19.0 0.0 2 8.4 0.0 2.8 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 CCD26264.1 - 0.0012 18.6 0.0 0.82 9.4 0.0 3.0 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 CCD26264.1 - 0.0012 18.1 0.0 0.064 12.5 0.0 3.1 2 1 1 3 3 3 1 Zeta toxin AAA_28 PF13521.6 CCD26264.1 - 0.0014 18.9 0.0 1 9.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CCD26264.1 - 0.0014 17.8 0.8 0.57 9.3 0.3 3.4 2 2 0 2 2 2 1 Protein of unknown function (DUF815) AAA_21 PF13304.6 CCD26264.1 - 0.0016 18.3 5.2 0.82 9.4 0.0 3.9 3 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 CCD26264.1 - 0.0017 18.1 0.0 1.5 8.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CCD26264.1 - 0.0018 18.7 0.0 3.1 8.2 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 CCD26264.1 - 0.003 18.1 2.5 2.5 8.7 0.0 3.3 4 0 0 4 4 2 1 AAA domain AAA_24 PF13479.6 CCD26264.1 - 0.0036 17.0 0.0 2.2 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 CCD26264.1 - 0.0038 17.4 0.1 1.2 9.4 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_6 PF12774.7 CCD26264.1 - 0.004 16.2 0.1 0.44 9.5 0.0 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_25 PF13481.6 CCD26264.1 - 0.0078 15.8 0.0 0.88 9.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 CCD26264.1 - 0.0094 15.3 0.1 1.1 8.6 0.0 2.8 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 CCD26264.1 - 0.0096 15.6 0.0 1.7 8.2 0.0 2.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Bac_DnaA PF00308.18 CCD26264.1 - 0.01 15.7 0.3 2.6 7.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial dnaA protein PhoH PF02562.16 CCD26264.1 - 0.013 15.0 0.0 0.47 9.9 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 CCD26264.1 - 0.026 14.5 0.3 2.6 8.0 0.0 3.5 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CCD26264.1 - 0.035 14.5 3.0 11 6.3 0.3 3.9 2 2 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CCD26264.1 - 0.04 14.0 1.0 2.7 8.1 0.0 3.8 4 0 0 4 4 3 0 50S ribosome-binding GTPase AAA_33 PF13671.6 CCD26264.1 - 0.093 12.9 0.0 11 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain NADH-UOR_E PF16514.5 CCD26264.1 - 0.1 12.9 1.5 0.56 10.6 0.1 3.0 3 0 0 3 3 1 0 putative NADH-ubiquinone oxidoreductase chain E AAA_3 PF07726.11 CCD26264.1 - 0.18 11.7 0.3 3.3 7.6 0.0 2.9 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF4094 PF13334.6 CCD26264.1 - 1.2 9.6 4.0 1.5 9.3 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) YabA PF06156.13 CCD26264.1 - 1.7 9.3 5.3 5.8 7.6 4.6 2.3 2 0 0 2 2 1 0 Initiation control protein YabA AAA_23 PF13476.6 CCD26264.1 - 2.4 8.6 26.2 14 6.1 0.8 4.1 2 2 0 2 2 2 0 AAA domain SET PF00856.28 CCD26265.1 - 9e-21 75.0 0.4 3.2e-20 73.2 0.0 1.9 2 0 0 2 2 2 1 SET domain EF-hand_7 PF13499.6 CCD26265.1 - 0.03 14.8 0.6 2 8.9 0.2 2.9 2 0 0 2 2 2 0 EF-hand domain pair Mrpl_C PF18502.1 CCD26265.1 - 0.59 10.4 6.4 6.8 7.0 0.6 2.6 1 1 1 2 2 2 0 54S ribosomal protein L8 C-terminal domain ANAPC2 PF08672.11 CCD26265.1 - 0.62 10.6 0.0 0.62 10.6 0.0 3.1 4 0 0 4 4 4 0 Anaphase promoting complex (APC) subunit 2 Pex24p PF06398.11 CCD26266.1 - 1.7e-75 254.3 10.5 2.4e-75 253.8 10.5 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Rpr2 PF04032.16 CCD26267.1 - 1.1e-11 44.8 0.2 1.1e-11 44.8 0.2 2.2 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.7 CCD26267.1 - 0.052 13.6 0.1 0.11 12.5 0.1 1.5 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 CCD26267.1 - 0.23 11.2 0.2 0.23 11.2 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.25 CCD26268.1 - 3.1e-76 256.2 0.1 5.4e-76 255.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain AdenylateSensor PF16579.5 CCD26268.1 - 8.1e-54 181.1 5.9 4.2e-28 98.2 0.1 3.4 2 1 1 3 3 3 2 Adenylate sensor of SNF1-like protein kinase Pkinase_Tyr PF07714.17 CCD26268.1 - 2.3e-38 132.0 0.0 3.9e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.11 CCD26268.1 - 1.1e-19 70.2 1.5 1.1e-19 70.2 1.5 2.3 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 CCD26268.1 - 1.6e-09 37.5 0.0 2.6e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CCD26268.1 - 9.3e-06 25.4 1.0 2.3e-05 24.1 1.0 1.6 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CCD26268.1 - 0.00026 20.0 0.4 0.00026 20.0 0.4 2.2 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CCD26268.1 - 0.0033 16.8 0.2 0.0066 15.8 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCD26268.1 - 0.035 14.0 0.1 0.74 9.7 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family NLRC4_HD PF17889.1 CCD26268.1 - 0.95 9.8 4.9 8.2 6.8 0.2 3.2 3 0 0 3 3 3 0 NLRC4 helical domain DUF2470 PF10615.9 CCD26269.1 - 0.031 14.9 0.0 0.058 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) BSMAP PF12280.8 CCD26270.1 - 0.56 10.4 3.9 0.4 10.9 0.5 2.4 2 0 0 2 2 2 0 Brain specific membrane anchored protein TRAPP PF04051.16 CCD26271.1 - 1.6e-49 167.4 0.0 3.1e-49 166.5 0.0 1.5 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component SelP_N PF04592.14 CCD26271.1 - 0.23 10.8 5.2 0.36 10.2 5.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ribosomal_L27e PF01777.18 CCD26272.1 - 5.5e-37 126.0 7.9 8.4e-37 125.4 7.9 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CCD26272.1 - 0.00084 19.2 2.0 0.0016 18.3 2.0 1.5 1 0 0 1 1 1 1 KOW motif Mito_carr PF00153.27 CCD26273.1 - 1.2e-08 34.7 0.0 0.009 15.9 0.0 3.3 3 1 0 3 3 3 2 Mitochondrial carrier protein Dpy-30 PF05186.13 CCD26274.1 - 1.5e-15 56.6 0.0 2.1e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif EzrA PF06160.12 CCD26275.1 - 0.0007 17.9 2.0 0.0007 17.9 2.0 2.2 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA Spc7 PF08317.11 CCD26275.1 - 0.0011 17.9 7.9 0.0021 17.0 1.1 2.1 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF948 PF06103.11 CCD26275.1 - 0.0014 18.9 9.1 0.057 13.7 5.3 3.3 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) SNARE PF05739.19 CCD26275.1 - 0.0014 18.6 0.1 0.0014 18.6 0.1 3.1 4 0 0 4 4 3 1 SNARE domain DUF892 PF05974.12 CCD26275.1 - 0.0022 18.1 2.5 0.01 15.9 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF892) Syntaxin-6_N PF09177.11 CCD26275.1 - 0.0026 18.3 8.1 0.013 16.0 4.1 3.0 2 1 1 3 3 3 1 Syntaxin 6, N-terminal TMPIT PF07851.13 CCD26275.1 - 0.0027 17.0 2.0 0.089 12.0 1.0 2.1 2 0 0 2 2 2 1 TMPIT-like protein CEP63 PF17045.5 CCD26275.1 - 0.0029 17.6 6.6 0.078 12.9 0.2 2.0 2 0 0 2 2 2 1 Centrosomal protein of 63 kDa Sec20 PF03908.13 CCD26275.1 - 0.0031 17.4 7.4 0.024 14.5 0.1 3.1 2 1 1 3 3 3 1 Sec20 DUF745 PF05335.13 CCD26275.1 - 0.0035 17.1 3.4 1.2 8.8 0.2 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF745) KxDL PF10241.9 CCD26275.1 - 0.0054 17.0 11.2 1.1 9.6 0.2 3.5 3 1 0 3 3 3 1 Uncharacterized conserved protein Perilipin PF03036.16 CCD26275.1 - 0.0062 15.6 2.9 0.35 9.8 0.1 2.2 2 0 0 2 2 2 1 Perilipin family THOC7 PF05615.13 CCD26275.1 - 0.0094 16.2 5.0 0.85 9.9 0.2 2.5 2 1 0 2 2 2 1 Tho complex subunit 7 Microtub_bd PF16796.5 CCD26275.1 - 0.013 15.4 0.2 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 Microtubule binding DUF1664 PF07889.12 CCD26275.1 - 0.014 15.5 11.0 1.3 9.1 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) SKA1 PF07160.12 CCD26275.1 - 0.015 15.2 9.1 0.58 10.0 3.2 2.6 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF2408 PF10303.9 CCD26275.1 - 0.017 15.7 4.2 0.25 11.9 2.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Prominin PF05478.11 CCD26275.1 - 0.021 12.8 7.6 0.069 11.1 0.7 2.1 1 1 1 2 2 2 0 Prominin Tweety PF04906.13 CCD26275.1 - 0.022 13.5 6.6 0.45 9.1 1.1 2.5 2 1 0 2 2 2 0 Tweety FliJ PF02050.16 CCD26275.1 - 0.033 14.4 5.7 8 6.7 0.1 3.1 3 0 0 3 3 3 0 Flagellar FliJ protein UPF0242 PF06785.11 CCD26275.1 - 0.033 14.3 15.5 1.5 8.9 1.1 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF2207 PF09972.9 CCD26275.1 - 0.04 12.7 2.1 0.081 11.7 0.0 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) MHC2-interact PF09307.10 CCD26275.1 - 0.051 13.6 0.1 7.7 6.6 0.0 2.4 2 0 0 2 2 2 0 CLIP, MHC2 interacting SlyX PF04102.12 CCD26275.1 - 0.068 13.8 15.4 9 7.0 0.9 4.4 2 2 2 4 4 4 0 SlyX MPS2 PF17060.5 CCD26275.1 - 0.075 12.3 0.2 0.075 12.3 0.2 2.5 1 1 0 2 2 2 0 Monopolar spindle protein 2 YtxH PF12732.7 CCD26275.1 - 0.083 13.4 1.2 2.6 8.7 1.2 3.0 1 1 0 1 1 1 0 YtxH-like protein RIG-I_C PF18119.1 CCD26275.1 - 0.085 12.9 6.0 1.3 9.0 0.2 2.6 2 1 0 2 2 2 0 RIG-I receptor C-terminal domain ApoLp-III PF07464.11 CCD26275.1 - 0.086 12.9 7.7 0.63 10.1 5.8 2.8 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF5082 PF16888.5 CCD26275.1 - 0.09 13.1 9.3 0.32 11.3 0.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) FlaC_arch PF05377.11 CCD26275.1 - 0.098 13.1 9.2 3.9 7.9 1.9 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) RmuC PF02646.16 CCD26275.1 - 0.098 11.8 8.4 0.59 9.2 0.3 2.7 2 1 1 3 3 3 0 RmuC family Allexi_40kDa PF05549.11 CCD26275.1 - 0.1 12.1 10.7 0.084 12.4 4.9 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein Laminin_II PF06009.12 CCD26275.1 - 0.1 12.6 10.6 0.96 9.5 6.7 2.8 2 1 0 2 2 2 0 Laminin Domain II Nup88 PF10168.9 CCD26275.1 - 0.11 10.3 6.3 1.1 6.9 0.6 2.0 2 0 0 2 2 2 0 Nuclear pore component LXG PF04740.12 CCD26275.1 - 0.12 12.1 15.0 2 8.1 6.2 2.8 1 1 1 2 2 2 0 LXG domain of WXG superfamily Imm1 PF14430.6 CCD26275.1 - 0.12 13.0 0.3 0.21 12.2 0.3 1.4 1 0 0 1 1 1 0 Immunity protein Imm1 Baculo_PEP_C PF04513.12 CCD26275.1 - 0.16 12.0 8.3 0.25 11.4 6.0 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.12 CCD26275.1 - 0.18 12.0 4.8 7.7 6.8 0.5 3.6 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Baculo_p24 PF05073.12 CCD26275.1 - 0.2 11.4 6.9 0.073 12.9 3.4 1.8 2 0 0 2 2 2 0 Baculovirus P24 capsid protein Cob_adeno_trans PF01923.18 CCD26275.1 - 0.23 11.6 1.6 0.41 10.8 0.3 1.9 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DUF1054 PF06335.12 CCD26275.1 - 0.29 11.0 1.7 0.46 10.4 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1054) DUF1043 PF06295.12 CCD26275.1 - 0.32 11.0 12.6 0.98 9.4 2.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1043) FliD_N PF02465.18 CCD26275.1 - 0.34 11.6 9.6 0.25 12.0 1.0 3.0 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Fez1 PF06818.15 CCD26275.1 - 0.36 11.2 8.9 6.3 7.2 8.4 2.0 1 1 0 1 1 1 0 Fez1 DUF1690 PF07956.11 CCD26275.1 - 0.38 11.2 7.6 0.87 10.0 3.2 2.3 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) PIN_8 PF18476.1 CCD26275.1 - 0.4 10.5 7.8 1.4 8.7 2.1 2.2 1 1 1 2 2 2 0 PIN like domain TMF_TATA_bd PF12325.8 CCD26275.1 - 0.46 10.7 11.8 4.7 7.5 5.1 3.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding USP8_interact PF08941.10 CCD26275.1 - 0.5 10.2 6.1 0.16 11.8 0.7 2.2 2 0 0 2 2 2 0 USP8 interacting EspB PF05802.11 CCD26275.1 - 0.53 10.3 6.1 0.48 10.4 0.6 2.4 2 1 0 2 2 2 0 Enterobacterial EspB protein TPR_MLP1_2 PF07926.12 CCD26275.1 - 0.63 10.1 7.8 0.97 9.5 2.4 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Noelin-1 PF12308.8 CCD26275.1 - 0.67 10.0 7.6 1 9.4 0.3 2.8 2 1 1 3 3 3 0 Neurogenesis glycoprotein BshC PF10079.9 CCD26275.1 - 0.7 8.6 5.3 0.34 9.6 1.0 1.9 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC Fzo_mitofusin PF04799.13 CCD26275.1 - 0.76 9.3 7.1 4.7 6.7 3.4 2.8 2 1 1 3 3 3 0 fzo-like conserved region Serine_rich PF08824.10 CCD26275.1 - 0.81 9.7 7.1 0.28 11.2 1.5 2.2 2 0 0 2 2 2 0 Serine rich protein interaction domain Fib_alpha PF08702.10 CCD26275.1 - 0.98 9.6 13.7 0.79 9.9 7.1 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family YlqD PF11068.8 CCD26275.1 - 1.3 9.4 12.3 2.2 8.7 1.5 3.0 2 1 1 3 3 3 0 YlqD protein DUF4549 PF15082.6 CCD26275.1 - 1.3 8.8 3.8 5.7 6.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4549) Osmo_CC PF08946.10 CCD26275.1 - 2.2 8.6 7.4 2.6 8.3 0.3 3.1 2 2 1 3 3 2 0 Osmosensory transporter coiled coil Occludin_ELL PF07303.13 CCD26275.1 - 2.4 8.9 10.5 11 6.8 3.2 3.1 2 1 0 2 2 2 0 Occludin homology domain YkyA PF10368.9 CCD26275.1 - 2.8 7.6 11.5 6.6 6.4 5.6 2.9 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein Prefoldin PF02996.17 CCD26275.1 - 3.7 7.5 10.2 1 9.3 1.0 3.2 2 1 1 3 3 3 0 Prefoldin subunit DUF16 PF01519.16 CCD26275.1 - 4.6 7.8 17.2 11 6.6 2.9 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 V_ATPase_I PF01496.19 CCD26275.1 - 5.7 4.7 6.4 8.2 4.2 0.6 2.2 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family PhaP_Bmeg PF09602.10 CCD26275.1 - 6.1 6.8 12.6 0.45 10.4 0.5 3.0 1 1 2 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF4200 PF13863.6 CCD26275.1 - 6.3 7.2 9.8 0.62 10.5 2.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Med9 PF07544.13 CCD26275.1 - 6.5 6.9 13.6 4.9 7.3 0.7 3.9 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 V-SNARE_C PF12352.8 CCD26275.1 - 8 6.8 8.6 24 5.3 3.4 2.9 2 1 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Sec2p PF06428.11 CCD26275.1 - 8.7 6.4 15.4 0.43 10.6 0.4 3.6 2 2 1 3 3 3 0 GDP/GTP exchange factor Sec2p Pkinase PF00069.25 CCD26276.1 - 6.9e-65 219.0 0.0 1e-64 218.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26276.1 - 3.2e-30 105.3 0.0 5.1e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD26276.1 - 9.5e-09 35.0 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CCD26276.1 - 0.0043 15.9 0.0 0.014 14.2 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CCD26276.1 - 0.0087 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCD26276.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 CCD26276.1 - 0.015 14.9 0.1 0.077 12.6 0.0 2.1 2 0 0 2 2 2 0 RIO1 family FTA2 PF13095.6 CCD26276.1 - 0.016 14.9 1.1 3.3 7.3 0.0 2.5 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SpoU_sub_bind PF08032.12 CCD26276.1 - 0.13 12.5 0.6 0.38 11.0 0.1 2.0 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding BLOC1S3 PF15753.5 CCD26277.1 - 0.1 12.7 0.4 0.1 12.7 0.4 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF3020 PF11223.8 CCD26278.1 - 1.5e-18 67.0 6.8 1.5e-18 67.0 6.8 8.4 8 2 0 8 8 8 1 Protein of unknown function (DUF3020) RNA_Me_trans PF04252.13 CCD26279.1 - 2.2e-78 262.4 0.0 2.5e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase PRP3 PF08572.10 CCD26280.1 - 3.1e-56 190.6 20.1 7.3e-56 189.4 19.8 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CCD26280.1 - 7.5e-31 107.2 1.4 7.5e-31 107.2 1.4 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF1115) PBP PF01161.20 CCD26281.1 - 4.1e-21 75.7 0.1 5.6e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein MAT1 PF06391.13 CCD26282.1 - 2.3e-71 239.8 17.1 3e-71 239.5 17.1 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 CCD26282.1 - 2.8e-27 94.4 8.0 4.8e-27 93.6 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCD26282.1 - 0.00038 20.2 4.5 0.00079 19.2 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCD26282.1 - 0.00069 19.9 6.6 0.0012 19.1 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CCD26282.1 - 0.0011 18.8 5.8 0.0019 18.0 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCD26282.1 - 0.0084 16.0 5.3 0.039 13.8 5.4 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FliS PF02561.14 CCD26282.1 - 0.009 16.3 4.2 0.011 16.0 1.6 2.2 1 1 0 2 2 2 1 Flagellar protein FliS zf-RING_UBOX PF13445.6 CCD26282.1 - 0.06 13.4 6.9 0.14 12.2 6.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CCD26282.1 - 0.096 12.7 8.6 1.2 9.1 9.1 2.2 1 1 1 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 CCD26282.1 - 0.85 9.5 8.8 6.9 6.6 3.3 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CCD26282.1 - 1 9.2 8.9 9.4 6.1 9.2 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1635 PF07795.11 CCD26282.1 - 2.3 8.0 9.4 3.2 7.5 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF87 PF01935.17 CCD26282.1 - 4.1 7.4 7.9 0.72 9.9 2.6 1.8 1 1 1 2 2 2 0 Helicase HerA, central domain TMEM52 PF14979.6 CCD26283.1 - 0.076 12.9 0.4 0.095 12.6 0.4 1.2 1 0 0 1 1 1 0 Transmembrane 52 MRP-L28 PF09812.9 CCD26284.1 - 4.8e-27 95.1 0.9 6.3e-27 94.7 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 tRNA-synt_His PF13393.6 CCD26284.1 - 0.058 12.6 0.2 0.078 12.2 0.2 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase zf-C2H2_4 PF13894.6 CCD26285.1 - 0.0076 17.0 17.3 0.02 15.7 3.0 3.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CCD26285.1 - 0.017 15.5 5.0 0.017 15.5 5.0 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCD26285.1 - 0.025 15.0 0.6 0.025 15.0 0.6 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_3rep PF18868.1 CCD26285.1 - 0.46 11.2 11.6 0.18 12.5 1.0 3.0 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats Rubredoxin_2 PF18073.1 CCD26285.1 - 2.6 7.8 5.6 29 4.5 0.1 2.7 2 0 0 2 2 2 0 Rubredoxin metal binding domain CDC24 PF06395.11 CCD26286.1 - 1.5e-37 127.7 3.2 3.3e-37 126.6 0.8 3.0 3 0 0 3 3 3 1 CDC24 Calponin RhoGEF PF00621.20 CCD26286.1 - 2.8e-26 92.9 7.5 2.8e-26 92.9 7.5 3.7 4 1 0 4 4 4 1 RhoGEF domain PH_10 PF15411.6 CCD26286.1 - 3.1e-23 82.4 10.8 1.9e-13 50.7 2.9 3.8 3 1 1 4 4 4 2 Pleckstrin homology domain SR-25 PF10500.9 CCD26286.1 - 0.0063 16.1 9.6 0.0063 16.1 9.6 5.1 5 0 0 5 5 5 1 Nuclear RNA-splicing-associated protein PH PF00169.29 CCD26286.1 - 0.046 14.2 2.9 0.56 10.7 2.9 3.0 1 1 0 1 1 1 0 PH domain Cyclin_N PF00134.23 CCD26287.1 - 1.5e-25 89.4 2.8 3.3e-25 88.3 2.8 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyto_heme_lyase PF01265.17 CCD26288.1 - 7.7e-97 324.4 8.4 1.8e-96 323.2 8.4 1.5 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase PK PF00224.21 CCD26289.1 - 2.4e-168 559.4 2.0 3.1e-168 559.1 2.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CCD26289.1 - 2e-33 115.1 0.0 6.9e-33 113.4 0.0 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CCD26289.1 - 3.7e-05 23.0 0.5 8e-05 21.9 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Mtd_N PF18454.1 CCD26289.1 - 0.031 14.3 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 Major tropism determinant N-terminal domain Sulfotransfer_1 PF00685.27 CCD26289.1 - 0.22 11.0 0.0 0.44 10.0 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase domain HLH PF00010.26 CCD26290.1 - 5.7e-15 55.0 1.2 1.8e-14 53.4 1.2 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_transf_90 PF05686.12 CCD26290.1 - 0.014 14.4 0.9 0.014 14.4 0.9 1.6 1 1 1 2 2 2 0 Glycosyl transferase family 90 Hyphal_reg_CWP PF11765.8 CCD26291.1 - 1.4e-44 152.4 13.4 1.4e-44 152.4 13.4 1.6 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal G8 PF10162.9 CCD26291.1 - 0.033 14.3 4.7 0.1 12.7 1.8 2.9 2 1 0 2 2 2 0 G8 domain Mis12 PF05859.12 CCD26292.1 - 4.6e-40 136.8 1.4 4.6e-40 136.8 1.4 1.8 2 1 0 2 2 2 1 Mis12 protein A_deaminase_N PF08451.11 CCD26292.1 - 0.22 11.9 2.9 0.23 11.8 0.1 2.2 1 1 1 2 2 2 0 Adenosine/AMP deaminase N-terminal MMR_HSR1_Xtn PF16897.5 CCD26293.1 - 2.5e-37 127.1 0.0 4.4e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CCD26293.1 - 2.4e-22 78.7 0.0 4.8e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CCD26293.1 - 3.6e-20 72.2 0.0 7.1e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCD26293.1 - 5.2e-10 39.1 0.1 1.2e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CCD26293.1 - 0.0049 16.9 0.4 4.1 7.4 0.0 2.2 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 CCD26293.1 - 0.012 14.6 0.1 0.028 13.4 0.1 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 CCD26293.1 - 0.014 15.7 0.1 8.8 6.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain Arf PF00025.21 CCD26293.1 - 0.17 11.3 0.2 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CCD26293.1 - 0.35 10.8 1.5 3 7.7 0.2 2.7 3 0 0 3 3 3 0 RsgA GTPase RNA_pol_Rpb1_5 PF04998.17 CCD26294.1 - 3.5e-99 331.6 6.6 7.6e-98 327.2 2.4 3.2 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CCD26294.1 - 1.4e-70 236.8 0.2 3.7e-70 235.5 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CCD26294.1 - 2.9e-39 134.5 0.3 2.6e-38 131.4 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 CCD26294.1 - 7.8e-26 91.1 1.3 7.8e-26 91.1 1.3 3.8 4 1 0 4 4 4 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 CCD26294.1 - 1.3e-24 86.2 0.0 1.1e-23 83.2 0.0 2.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Phage_int_SAM_5 PF13102.6 CCD26294.1 - 0.31 11.4 3.2 2.5 8.5 2.4 2.8 2 0 0 2 2 2 0 Phage integrase SAM-like domain SWIRM PF04433.17 CCD26295.1 - 7.3e-10 39.1 0.0 1.8e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain SR-25 PF10500.9 CCD26295.1 - 4.6 6.8 11.2 8.9 5.9 10.8 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3589 PF12141.8 CCD26296.1 - 3.8e-83 279.7 8.5 2.7e-52 178.0 0.1 3.0 2 1 0 2 2 2 2 Beta-mannosyltransferases bZIP_2 PF07716.15 CCD26298.1 - 6.5e-08 32.5 7.2 6.5e-08 32.5 7.2 2.8 2 1 1 3 3 3 1 Basic region leucine zipper LRS4 PF10422.9 CCD26300.1 - 4.3e-20 72.3 27.6 4.3e-20 72.3 27.6 2.2 1 1 1 2 2 2 1 Monopolin complex subunit LRS4 FlxA PF14282.6 CCD26300.1 - 0.0088 16.0 7.5 0.0088 16.0 7.5 3.0 3 0 0 3 3 3 1 FlxA-like protein APG6_N PF17675.1 CCD26300.1 - 0.78 10.3 11.9 0.046 14.2 5.2 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 CCD26300.1 - 1.3 8.9 6.8 0.093 12.5 1.2 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF3450 PF11932.8 CCD26300.1 - 4.6 6.5 8.8 0.15 11.4 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Mannosyl_trans3 PF11051.8 CCD26301.1 - 1.8e-74 250.6 1.8 1.8e-74 250.6 1.8 1.5 2 0 0 2 2 2 1 Mannosyltransferase putative Thioredoxin_8 PF13905.6 CCD26301.1 - 0.13 12.6 1.3 0.69 10.3 0.4 2.5 1 1 1 2 2 2 0 Thioredoxin-like ABC2_membrane PF01061.24 CCD26302.1 - 1e-62 211.3 63.7 1.4e-34 119.4 28.7 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 CCD26302.1 - 4.6e-28 98.4 0.0 3.6e-16 59.9 0.1 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CCD26302.1 - 1.4e-23 82.6 6.8 2.5e-21 75.4 0.3 3.6 4 0 0 4 4 3 2 CDR ABC transporter RsgA_GTPase PF03193.16 CCD26302.1 - 9e-06 25.7 0.2 1.9e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 CCD26302.1 - 4.8e-05 23.3 2.6 0.0061 16.4 0.2 2.9 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCD26302.1 - 0.0002 20.9 0.4 0.0065 15.9 0.4 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CCD26302.1 - 0.00047 20.7 0.0 0.0011 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCD26302.1 - 0.0031 17.9 0.3 0.0067 16.8 0.3 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 CCD26302.1 - 0.0057 16.3 0.2 0.015 14.9 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CCD26302.1 - 0.022 15.0 0.2 0.071 13.4 0.2 1.9 1 1 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 CCD26302.1 - 0.025 13.7 60.0 0.18 10.9 15.2 3.6 2 2 1 3 3 3 0 ABC-2 family transporter protein AAA_29 PF13555.6 CCD26302.1 - 0.044 13.5 0.2 0.12 12.1 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 CCD26302.1 - 0.079 13.5 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CCD26302.1 - 0.18 11.9 0.3 0.73 9.9 0.2 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP1_TIP1 PF00660.17 CCD26303.1 - 8.6e-37 125.2 2.4 1.9e-36 124.1 2.4 1.6 1 0 0 1 1 1 1 Seripauperin and TIP1 family DUF1189 PF06691.11 CCD26303.1 - 0.035 13.7 0.3 0.045 13.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) SOG2 PF10428.9 CCD26303.1 - 0.12 11.6 36.0 0.17 11.1 36.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SAPS PF04499.15 CCD26303.1 - 0.66 8.7 3.8 0.77 8.5 3.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CytochromB561_N PF09786.9 CCD26303.1 - 0.69 8.8 26.4 0.76 8.7 26.4 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal FAM196 PF15265.6 CCD26303.1 - 2.7 7.4 19.3 3.3 7.1 19.3 1.1 1 0 0 1 1 1 0 FAM196 family TFIIA PF03153.13 CCD26303.1 - 7.3 6.5 13.7 9 6.2 13.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SRP1_TIP1 PF00660.17 CCD26304.1 - 1.7e-36 124.2 2.9 3.3e-36 123.3 2.9 1.5 1 0 0 1 1 1 1 Seripauperin and TIP1 family SOG2 PF10428.9 CCD26304.1 - 0.18 11.0 22.9 0.25 10.5 22.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DDHD PF02862.17 CCD26304.1 - 0.24 11.5 7.1 0.41 10.8 7.1 1.3 1 0 0 1 1 1 0 DDHD domain DUF572 PF04502.13 CCD26304.1 - 1.6 8.3 4.4 1.9 8.0 4.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Tmemb_cc2 PF10267.9 CCD26304.1 - 2 7.5 7.8 2.4 7.2 7.8 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein GEMIN8 PF15348.6 CCD26304.1 - 3.8 7.7 5.1 5.3 7.3 5.1 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 SPX PF03105.19 CCD26304.1 - 4.7 7.0 16.9 5.7 6.7 16.9 1.1 1 0 0 1 1 1 0 SPX domain GREB1 PF15782.5 CCD26304.1 - 4.8 4.2 10.5 4.9 4.1 10.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GCOM2 PF15328.6 CCD26304.1 - 6.1 7.2 6.5 8.1 6.8 6.5 1.3 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 AhpC-TSA PF00578.21 CCD26305.1 - 8e-27 93.6 0.0 1.5e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CCD26305.1 - 6.1e-18 64.9 0.0 1.1e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Redoxin FPV060 PF17614.2 CCD26305.1 - 0.11 11.9 0.7 2.3 7.6 0.1 2.1 1 1 1 2 2 2 0 Viral CC-type chemokine Lipase_GDSL_3 PF14606.6 CCD26305.1 - 0.38 10.9 1.9 0.75 9.9 1.9 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family CRAL_TRIO PF00650.20 CCD26306.1 - 2.9e-36 124.6 0.0 3.7e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CCD26306.1 - 0.00088 19.4 0.0 0.0012 19.0 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain X8 PF07983.13 CCD26306.1 - 0.0094 16.6 0.5 3.5 8.4 0.0 2.3 2 0 0 2 2 2 2 X8 domain DUF1769 PF08588.10 CCD26306.1 - 0.073 13.3 0.0 0.26 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1769) AAA PF00004.29 CCD26307.1 - 8e-11 42.5 0.0 2.3e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CCD26307.1 - 4.6e-07 29.9 0.1 1.2e-05 25.4 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 CCD26307.1 - 7.3e-05 22.6 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCD26307.1 - 0.00017 22.0 0.0 0.00042 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CCD26307.1 - 0.00048 20.7 0.5 0.052 14.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 CCD26307.1 - 0.0011 18.9 0.2 0.01 15.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CCD26307.1 - 0.0015 18.8 0.1 0.013 15.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CCD26307.1 - 0.0088 16.2 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CCD26307.1 - 0.027 14.8 0.0 0.11 12.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_assoc_2 PF16193.5 CCD26307.1 - 0.045 14.1 0.0 0.16 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA C-terminal domain IPT PF01745.16 CCD26307.1 - 0.072 12.5 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Isopentenyl transferase DEAD PF00270.29 CCD26307.1 - 0.11 12.3 0.2 8.2 6.2 0.0 3.2 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_5 PF07728.14 CCD26307.1 - 0.14 12.2 0.0 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) HrcA_DNA-bdg PF03444.15 CCD26307.1 - 0.19 11.4 0.3 1.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding AAA_17 PF13207.6 CCD26307.1 - 0.63 10.5 4.2 1 9.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain Hydin_ADK PF17213.3 CCD26307.1 - 7.9 6.7 9.7 1.3 9.3 0.1 3.1 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain HEAT PF02985.22 CCD26308.1 - 3.3e-06 26.9 0.0 5.8 7.5 0.0 5.5 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 CCD26308.1 - 1.2e-05 25.4 12.9 0.00052 20.1 1.4 5.9 5 1 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.10 CCD26308.1 - 0.002 17.9 0.1 0.77 9.5 0.0 3.5 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) NopRA1 PF16201.5 CCD26308.1 - 0.0025 17.4 1.8 3 7.4 0.0 3.8 4 0 0 4 4 4 2 Nucleolar pre-ribosomal-associated protein 1 DNApol3-delta_C PF09115.10 CCD26308.1 - 0.051 14.1 0.2 0.051 14.1 0.2 2.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal HEAT_EZ PF13513.6 CCD26308.1 - 0.071 13.6 0.0 3.9 8.1 0.0 3.5 4 0 0 4 4 4 0 HEAT-like repeat PHD PF00628.29 CCD26309.1 - 2.1e-13 49.9 19.8 3.6e-10 39.6 8.3 2.8 2 1 1 3 3 3 2 PHD-finger zf-BED PF02892.15 CCD26309.1 - 0.048 13.7 0.8 0.37 10.9 0.0 2.8 2 0 0 2 2 2 0 BED zinc finger Zn_ribbon_2 PF12674.7 CCD26309.1 - 0.074 13.7 2.7 0.35 11.6 2.7 2.2 1 0 0 1 1 1 0 Putative zinc ribbon domain dsDNA_bind PF01984.20 CCD26310.1 - 1.6e-27 95.9 1.5 2e-27 95.6 1.5 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain cwf18 PF08315.12 CCD26310.1 - 0.065 13.9 1.7 0.13 12.9 1.7 1.5 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor DNA_pol_phi PF04931.13 CCD26310.1 - 0.081 11.0 4.5 0.1 10.7 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cyt-b5 PF00173.28 CCD26311.1 - 2.9e-18 65.8 0.1 4.5e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF382 PF04037.13 CCD26311.1 - 0.063 13.4 1.2 1.1 9.5 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF382) HMG_box PF00505.19 CCD26312.1 - 6.8e-30 103.3 12.3 1.1e-14 54.5 2.2 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CCD26312.1 - 1.6e-21 76.7 9.4 5e-11 43.0 1.8 2.2 2 0 0 2 2 2 2 HMG-box domain DUF1299 PF06975.11 CCD26312.1 - 0.087 12.9 2.1 0.19 11.8 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1299) Arg_decarbox_C PF17944.1 CCD26312.1 - 0.18 12.4 2.4 0.72 10.5 0.1 2.8 3 1 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension KRAB PF01352.27 CCD26312.1 - 0.37 10.5 6.6 0.33 10.6 1.0 2.7 3 0 0 3 3 3 0 KRAB box Cg6151-P PF10233.9 CCD26313.1 - 1.3e-37 128.6 15.4 1.8e-37 128.1 15.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P ATG22 PF11700.8 CCD26313.1 - 0.66 8.5 9.3 1.1 7.9 9.3 1.2 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like zf-C2H2 PF00096.26 CCD26314.1 - 4.5e-05 23.7 12.8 5.2e-05 23.5 2.8 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD26314.1 - 7.5e-05 23.2 12.4 0.003 18.3 2.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 CCD26314.1 - 0.00049 20.3 1.7 0.00088 19.5 1.7 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 CCD26314.1 - 0.0056 16.7 1.8 0.0056 16.7 1.8 3.1 2 1 1 3 3 3 1 BED zinc finger zf-C2H2_2 PF12756.7 CCD26314.1 - 0.012 15.9 3.3 2 8.8 0.2 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) UPF0167 PF03691.14 CCD26314.1 - 0.03 14.1 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) zf-met PF12874.7 CCD26314.1 - 0.13 12.7 4.7 0.18 12.3 0.7 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCD26314.1 - 0.2 12.0 1.0 0.69 10.3 1.0 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CCD26314.1 - 2.2 8.9 16.1 5.6 7.6 3.8 4.0 4 0 0 4 4 4 0 Zinc-finger double domain NIF PF03031.18 CCD26316.1 - 5.1e-49 166.0 0.3 1.5e-48 164.5 0.1 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Mito_carr PF00153.27 CCD26317.1 - 6.8e-62 205.4 1.2 9.2e-23 80.0 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L14e PF01929.17 CCD26318.1 - 4.5e-33 113.6 1.0 6.9e-33 113.0 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CCD26318.1 - 2.1e-05 24.3 0.3 4.2e-05 23.3 0.3 1.5 1 0 0 1 1 1 1 KOW motif Oxysterol_BP PF01237.18 CCD26319.1 - 2.9e-88 296.2 1.0 1.3e-79 267.7 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein TRAM_LAG1_CLN8 PF03798.16 CCD26320.1 - 1.9e-37 129.0 28.7 1.9e-37 129.0 28.7 2.3 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CCD26320.1 - 6.6e-21 73.7 2.2 6.6e-21 73.7 2.2 2.2 2 0 0 2 2 2 1 TRAM1-like protein PQ-loop PF04193.14 CCD26321.1 - 2.1e-12 46.6 13.1 3e-10 39.7 3.4 3.5 2 1 1 3 3 3 2 PQ loop repeat DUF765 PF05570.11 CCD26321.1 - 0.027 14.6 1.4 0.046 13.9 1.4 1.3 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) ARD PF03079.14 CCD26322.1 - 2.6e-44 151.2 0.2 3.1e-44 150.9 0.2 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 CCD26322.1 - 3.8e-10 39.3 0.0 7.7e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CCD26322.1 - 2.3e-06 27.5 0.0 3.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 CCD26322.1 - 2.7e-05 23.8 0.0 3.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.6 CCD26322.1 - 0.017 14.9 0.0 0.036 13.8 0.0 1.4 1 1 0 1 1 1 0 Cupin-like domain JmjC PF02373.22 CCD26322.1 - 0.07 13.6 0.0 0.13 12.7 0.0 1.5 1 1 0 1 1 1 0 JmjC domain, hydroxylase bZIP_1 PF00170.21 CCD26323.1 - 1.1e-06 28.6 6.7 1.1e-06 28.6 6.7 2.7 2 1 1 3 3 3 1 bZIP transcription factor Fer2_2 PF01799.20 CCD26323.1 - 0.057 13.4 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 [2Fe-2S] binding domain Opy2 PF09463.10 CCD26323.1 - 0.44 10.9 10.2 0.61 10.5 1.2 2.6 2 0 0 2 2 2 0 Opy2 protein bZIP_2 PF07716.15 CCD26323.1 - 4.2 7.5 25.2 0.066 13.3 9.9 3.2 3 0 0 3 3 3 0 Basic region leucine zipper Rpr2 PF04032.16 CCD26325.1 - 2.5e-19 69.4 3.5 3.8e-19 68.8 3.5 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Proteasome PF00227.26 CCD26326.1 - 3e-56 189.9 0.0 4e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCD26326.1 - 2.6e-13 49.4 0.2 5.8e-13 48.3 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RNase_P_Rpp14 PF01900.19 CCD26327.1 - 2.1e-32 111.4 0.0 3e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family FlaC_arch PF05377.11 CCD26327.1 - 1.3 9.5 4.5 1.1 9.7 2.3 2.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) SKIP_SNW PF02731.15 CCD26328.1 - 4.4e-37 127.2 0.8 4.4e-37 127.2 0.8 1.9 2 0 0 2 2 2 1 SKIP/SNW domain Cellulase PF00150.18 CCD26330.1 - 3.8e-15 56.1 0.3 1.2e-09 38.0 0.1 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 CCD26330.1 - 1e-13 51.6 0.0 2.3e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 CCD26330.1 - 2.6e-05 24.0 0.0 5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 CCD26330.1 - 0.019 14.3 0.2 0.094 12.0 0.0 2.1 2 0 0 2 2 2 0 Beta-galactosidase Glyco_hydro_14 PF01373.17 CCD26330.1 - 0.022 13.7 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 DNA_primase_S PF01896.19 CCD26331.1 - 8.6e-65 218.1 0.8 1.2e-64 217.6 0.8 1.2 1 0 0 1 1 1 1 DNA primase small subunit DUF2205 PF10224.9 CCD26331.1 - 0.00082 19.3 1.4 0.0019 18.1 1.4 1.6 1 0 0 1 1 1 1 Short coiled-coil protein Zn_clus PF00172.18 CCD26332.1 - 2.4e-09 37.1 8.8 4.3e-09 36.3 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMPKBI PF04739.15 CCD26334.1 - 2.2e-20 72.7 0.9 2.2e-20 72.7 0.9 2.8 3 0 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 CCD26334.1 - 7e-09 35.8 0.0 1.9e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase PAP1 PF08601.10 CCD26335.1 - 3e-09 37.1 1.1 3e-09 37.1 1.1 3.6 1 1 1 3 3 3 1 Transcription factor PAP1 Rib_recp_KP_reg PF05104.12 CCD26335.1 - 0.25 12.4 6.3 0.53 11.3 6.3 1.4 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Peptidase_U57 PF05582.12 CCD26335.1 - 0.26 10.5 3.2 0.48 9.6 3.2 1.4 1 0 0 1 1 1 0 YabG peptidase U57 Dynein_light PF01221.18 CCD26336.1 - 1.4e-33 115.1 0.0 1.6e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 CCD26336.1 - 0.0016 19.1 0.0 0.0025 18.5 0.0 1.3 1 0 0 1 1 1 1 Ground-like domain Rpn9_C PF18261.1 CCD26337.1 - 2e-16 59.2 4.3 4.7e-16 58.1 4.3 1.7 1 0 0 1 1 1 1 Rpn9 C-terminal helix PCI PF01399.27 CCD26337.1 - 1.7e-14 54.2 0.6 1.7e-14 54.2 0.6 2.2 2 1 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 CCD26337.1 - 0.0049 16.9 1.1 0.013 15.5 0.2 2.1 2 1 0 2 2 2 1 CSN8/PSMD8/EIF3K family DUF236 PF03057.14 CCD26337.1 - 0.08 12.9 1.2 0.16 12.0 1.2 1.4 1 0 0 1 1 1 0 DUF236 repeat DUF2800 PF10926.8 CCD26337.1 - 0.16 11.2 0.1 0.27 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) Fur_reg_FbpB PF13040.6 CCD26337.1 - 5.4 6.6 10.3 0.23 11.0 0.5 3.3 3 0 0 3 3 3 0 Fur-regulated basic protein B Spt5-NGN PF03439.13 CCD26338.1 - 3.9e-06 26.7 0.0 8.6e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 CCD26338.1 - 0.0012 18.7 0.1 0.003 17.5 0.1 1.6 1 0 0 1 1 1 1 KOW motif Pro_dh PF01619.18 CCD26339.1 - 9.9e-58 196.0 0.2 1.4e-57 195.5 0.2 1.2 1 0 0 1 1 1 1 Proline dehydrogenase M16C_assoc PF08367.11 CCD26340.1 - 4.9e-74 248.6 1.3 7.4e-74 248.0 1.3 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 CCD26340.1 - 3.8e-27 95.5 0.3 1.2e-16 61.3 0.0 4.2 5 0 0 5 5 5 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CCD26340.1 - 3e-06 27.3 1.2 3.6e-05 23.8 0.0 2.7 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) RRM_1 PF00076.22 CCD26341.1 - 1.9e-31 107.7 0.6 4.7e-18 64.8 0.3 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCD26341.1 - 0.00061 19.6 0.0 0.027 14.3 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CCD26341.1 - 0.0011 18.6 0.0 0.0053 16.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD26341.1 - 0.037 14.1 0.1 0.28 11.3 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif PRCC PF10253.9 CCD26341.1 - 0.3 11.9 9.7 0.42 11.4 9.7 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting PIG-S PF10510.9 CCD26342.1 - 2.5e-127 425.9 7.9 3e-127 425.6 7.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF1611_N PF17396.2 CCD26342.1 - 0.00078 19.6 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1611_N) Rossmann-like domain TAFII28 PF04719.14 CCD26343.1 - 2.6e-28 97.9 2.9 6.8e-25 87.0 0.1 2.9 3 0 0 3 3 3 2 hTAFII28-like protein conserved region LCM PF04072.14 CCD26344.1 - 8.8e-20 71.4 0.0 1.4e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase PIG-P PF08510.12 CCD26345.1 - 4.3e-25 88.0 0.6 5.3e-25 87.7 0.6 1.1 1 0 0 1 1 1 1 PIG-P RRM_1 PF00076.22 CCD26346.1 - 0.00047 19.9 0.4 0.0011 18.8 0.4 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) T6PP_N PF18572.1 CCD26346.1 - 0.029 14.2 3.2 0.46 10.3 0.2 2.6 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain EamA PF00892.20 CCD26347.1 - 4.6e-08 33.3 39.8 1e-05 25.7 16.4 4.3 2 2 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 CCD26347.1 - 0.013 14.9 19.5 0.031 13.6 6.2 3.4 1 1 2 3 3 3 0 Triose-phosphate Transporter family DUF3180 PF11377.8 CCD26347.1 - 0.022 14.9 0.0 0.081 13.1 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) DUF3955 PF13127.6 CCD26347.1 - 0.023 14.5 3.0 0.023 14.5 3.0 5.5 6 0 0 6 6 6 0 Protein of unknown function (DUF3955) EMP24_GP25L PF01105.24 CCD26347.1 - 0.044 13.7 4.0 0.24 11.3 0.3 2.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD ETRAMP PF09716.10 CCD26347.1 - 0.046 13.8 7.4 0.35 11.0 0.1 3.6 3 1 1 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) DUF2615 PF11027.8 CCD26347.1 - 0.15 12.2 4.5 0.95 9.6 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2615) Sulf_transp PF04143.14 CCD26347.1 - 0.69 9.4 10.6 0.23 11.0 3.8 2.6 1 1 1 2 2 2 0 Sulphur transport PUNUT PF16913.5 CCD26347.1 - 1.5 7.9 31.3 0.0055 16.0 15.3 3.0 1 1 1 2 2 2 0 Purine nucleobase transmembrane transport EphA2_TM PF14575.6 CCD26347.1 - 4 8.4 5.9 10 7.1 0.1 3.6 3 2 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2976 PF11190.8 CCD26347.1 - 7.6 6.4 9.1 0.38 10.6 0.1 3.1 3 2 0 3 3 3 0 Protein of unknown function (DUF2976) GATA PF00320.27 CCD26348.1 - 5.1e-10 38.8 7.8 1.1e-09 37.7 7.8 1.6 1 0 0 1 1 1 1 GATA zinc finger DNA_pol_alpha_N PF12254.8 CCD26348.1 - 0.14 12.3 3.8 0.13 12.4 1.8 2.0 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal RNA_pol_Rbc25 PF08292.12 CCD26348.1 - 4 7.7 5.2 3.2 8.0 0.4 2.6 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 DOT1 PF08123.13 CCD26349.1 - 1.6e-84 282.5 0.1 3.4e-84 281.5 0.1 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_2 PF00891.18 CCD26349.1 - 0.022 14.0 0.1 0.32 10.2 0.1 2.3 1 1 0 1 1 1 0 O-methyltransferase domain Med13_N PF11597.8 CCD26350.1 - 1.8e-67 227.9 1.3 3.3e-67 227.1 1.3 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Med13_C PF06333.12 CCD26350.1 - 6.8e-27 94.6 5.3 4.9e-19 68.8 0.0 3.5 2 2 2 4 4 4 2 Mediator complex subunit 13 C-terminal domain DUF676 PF05057.14 CCD26351.1 - 2.2e-48 164.7 0.0 3.4e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 CCD26351.1 - 0.00013 21.9 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.11 CCD26351.1 - 0.00078 18.8 0.1 0.0013 18.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase PF00151.19 CCD26351.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipase ECM11 PF15463.6 CCD26352.1 - 1.3e-19 71.1 0.1 1.3e-19 71.1 0.1 2.2 2 1 1 3 3 3 1 Extracellular mutant protein 11 Ribosomal_S17e PF00833.18 CCD26353.1 - 2.7e-56 188.7 0.3 3.2e-56 188.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal S17 ZZ PF00569.17 CCD26354.1 - 1e-15 57.3 8.1 1.7e-15 56.6 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 CCD26354.1 - 1.6e-09 37.8 0.7 2.9e-09 37.0 0.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.17 CCD26354.1 - 1.2e-07 32.0 0.1 3.8e-06 27.1 0.0 2.8 3 0 0 3 3 3 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 CCD26354.1 - 8.6e-05 22.7 0.0 0.00025 21.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ARL2_Bind_BART PF11527.8 CCD26354.1 - 0.0047 17.0 0.9 0.011 15.8 0.6 1.9 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART Methyltransf_4 PF02390.17 CCD26354.1 - 0.012 15.0 0.2 0.026 14.0 0.2 1.5 1 0 0 1 1 1 0 Putative methyltransferase U3_assoc_6 PF08640.11 CCD26355.1 - 7.9e-30 102.8 1.9 7.9e-30 102.8 1.9 2.9 3 1 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 CCD26355.1 - 2e-05 23.9 2.8 0.0025 17.0 0.4 2.7 1 1 2 3 3 3 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 CCD26355.1 - 0.00072 20.2 0.0 1.6 9.8 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCD26355.1 - 0.0013 18.9 1.2 2.4 8.7 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Suf PF05843.14 CCD26355.1 - 0.0022 18.0 4.0 0.035 14.1 4.0 2.5 1 1 0 1 1 1 1 Suppressor of forked protein (Suf) TPR_11 PF13414.6 CCD26355.1 - 0.049 13.3 0.0 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 TPR repeat Nuclease_act PF08133.11 CCD26355.1 - 0.052 13.7 1.0 1.1 9.6 0.1 2.9 2 0 0 2 2 2 0 Anticodon nuclease activator family DUF3966 PF13110.6 CCD26355.1 - 0.13 12.2 1.2 0.29 11.1 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) Ribosomal_S13 PF00416.22 CCD26356.1 - 2.6e-57 192.7 2.7 3e-57 192.5 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CCD26356.1 - 0.0042 15.9 0.0 0.0059 15.4 0.0 1.2 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Metallophos PF00149.28 CCD26357.1 - 8e-07 29.8 0.8 1.9e-06 28.6 0.8 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AhpC-TSA PF00578.21 CCD26358.1 - 3e-33 114.4 0.0 6.2e-33 113.4 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CCD26358.1 - 1.1e-16 60.8 0.0 2.4e-16 59.8 0.0 1.4 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.9 CCD26358.1 - 5.2e-09 35.8 0.4 1.4e-08 34.5 0.1 1.9 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CCD26358.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC Guanylate_kin PF00625.21 CCD26359.1 - 4.4e-70 235.1 0.0 4.9e-70 234.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 CCD26359.1 - 1.2e-07 32.2 0.0 2e-07 31.6 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CCD26359.1 - 1.2e-06 28.8 0.0 6.7e-06 26.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CCD26359.1 - 6.3e-06 26.2 0.0 9e-05 22.5 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 CCD26359.1 - 1.9e-05 25.2 0.0 3.9e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CCD26359.1 - 4.4e-05 24.0 0.0 8e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 CCD26359.1 - 4.8e-05 23.2 0.2 0.0097 15.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 CCD26359.1 - 6.2e-05 23.3 0.0 0.00045 20.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CCD26359.1 - 0.00078 19.8 0.0 0.0035 17.7 0.0 2.0 2 1 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 CCD26359.1 - 0.00085 19.4 0.0 0.0013 18.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CCD26359.1 - 0.0012 18.8 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CCD26359.1 - 0.0014 18.3 2.4 0.014 15.1 0.2 2.5 2 1 0 2 2 2 1 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 CCD26359.1 - 0.0018 18.0 0.0 0.014 15.1 0.0 2.0 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 CCD26359.1 - 0.0028 17.9 0.0 0.0056 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CCD26359.1 - 0.0034 17.3 0.0 0.0073 16.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.9 CCD26359.1 - 0.0041 16.4 0.0 0.038 13.2 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CCD26359.1 - 0.007 16.1 0.0 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CCD26359.1 - 0.0092 16.4 0.1 0.029 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CCD26359.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.6 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 CCD26359.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 CCD26359.1 - 0.013 15.4 0.1 0.026 14.4 0.1 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea dNK PF01712.19 CCD26359.1 - 0.014 15.2 0.1 0.064 13.1 0.0 2.1 2 1 0 2 2 2 0 Deoxynucleoside kinase AAA PF00004.29 CCD26359.1 - 0.015 15.7 0.3 0.066 13.6 0.3 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CCD26359.1 - 0.015 14.4 0.0 0.047 12.7 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 CCD26359.1 - 0.018 15.2 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 CCD26359.1 - 0.019 14.9 0.0 0.025 14.5 0.0 1.4 1 1 0 1 1 1 0 NTPase AAA_23 PF13476.6 CCD26359.1 - 0.031 14.8 1.9 0.057 13.9 1.9 1.8 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 CCD26359.1 - 0.039 13.9 0.3 0.2 11.7 0.3 2.1 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CCD26359.1 - 0.042 13.4 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 CCD26359.1 - 0.059 12.6 0.1 0.28 10.4 0.0 1.7 1 1 0 2 2 2 0 KAP family P-loop domain FeoB_N PF02421.18 CCD26359.1 - 0.064 12.8 0.0 2.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_2 PF07724.14 CCD26359.1 - 0.07 13.2 0.1 0.75 9.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Cytidylate_kin PF02224.18 CCD26359.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase NB-ARC PF00931.22 CCD26359.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Thymidylate_kin PF02223.17 CCD26359.1 - 0.13 12.0 0.0 0.38 10.4 0.0 1.7 1 1 1 2 2 2 0 Thymidylate kinase Adeno_IVa2 PF02456.15 CCD26359.1 - 0.16 10.7 0.0 0.32 9.7 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein Na_H_Exchanger PF00999.21 CCD26360.1 - 3.3e-70 236.8 33.8 4.1e-70 236.5 33.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Myc_target_1 PF15179.6 CCD26360.1 - 0.061 13.2 2.8 0.14 12.1 1.0 2.1 2 0 0 2 2 2 0 Myc target protein 1 DUF4064 PF13273.6 CCD26360.1 - 3.4 8.0 18.0 0.071 13.4 1.4 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF4064) HECT PF00632.25 CCD26361.1 - 1.8e-94 316.7 0.1 4.3e-94 315.5 0.1 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 CCD26361.1 - 1e-57 196.2 2.7 1e-57 196.2 2.7 2.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF913 PF06025.12 CCD26361.1 - 1.9e-49 168.6 0.1 1.9e-49 168.6 0.1 2.7 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) UBM PF14377.6 CCD26361.1 - 2e-15 55.6 4.5 6.6e-10 38.1 0.2 2.6 2 0 0 2 2 2 2 Ubiquitin binding region FidL_like PF15941.5 CCD26361.1 - 0.21 12.1 4.7 0.14 12.6 0.2 3.3 2 0 0 2 2 2 0 FidL-like putative membrane protein DUF3361 PF11841.8 CCD26361.1 - 1.9 8.4 11.0 0.19 11.7 0.6 4.4 3 2 0 3 3 3 0 Domain of unknown function (DUF3361) MSC PF09402.10 CCD26362.1 - 3.3e-84 283.2 2.6 3.3e-84 283.2 2.6 2.8 3 0 0 3 3 3 2 Man1-Src1p-C-terminal domain HeH PF12949.7 CCD26362.1 - 1.4e-16 59.9 1.0 5.6e-16 58.0 1.0 2.2 1 0 0 1 1 1 1 HeH/LEM domain HAD_2 PF13419.6 CCD26362.1 - 1.9 8.5 5.8 0.81 9.7 1.8 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DHHC PF01529.20 CCD26363.1 - 6.1e-28 97.6 10.0 6.1e-28 97.6 10.0 2.2 2 0 0 2 2 2 2 DHHC palmitoyltransferase Ly49 PF08391.10 CCD26363.1 - 0.018 15.4 2.5 0.029 14.7 0.2 2.3 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Tmemb_9 PF05434.11 CCD26363.1 - 0.13 12.1 0.9 2.9 7.8 0.1 2.2 2 0 0 2 2 2 0 TMEM9 COPIIcoated_ERV PF07970.12 CCD26364.1 - 2.5e-73 246.6 2.4 3.4e-73 246.2 2.4 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CCD26364.1 - 3.9e-29 100.8 0.1 8.1e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) GATA PF00320.27 CCD26365.1 - 5e-10 38.8 7.8 1.1e-09 37.7 7.8 1.7 1 0 0 1 1 1 1 GATA zinc finger DHHC PF01529.20 CCD26365.1 - 0.033 14.3 0.4 0.078 13.1 0.4 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF1180 PF06679.12 CCD26365.1 - 0.036 14.5 0.2 0.036 14.5 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1180) ArfGap PF01412.18 CCD26365.1 - 0.094 12.8 0.3 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DUF3453 PF11935.8 CCD26366.1 - 1.6e-48 165.4 0.8 4.4e-48 163.9 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) GCV_H PF01597.19 CCD26367.1 - 3.3e-44 149.7 0.7 4.4e-44 149.3 0.7 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein BolA PF01722.18 CCD26368.1 - 4.4e-24 84.6 1.4 5.7e-24 84.2 1.4 1.2 1 0 0 1 1 1 1 BolA-like protein Mto2_bdg PF12808.7 CCD26369.1 - 2.6e-06 27.6 10.4 2.6e-06 27.6 10.4 3.6 3 0 0 3 3 3 1 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_2 PF07716.15 CCD26369.1 - 0.018 15.1 5.9 0.018 15.1 5.9 7.0 4 2 1 7 7 7 0 Basic region leucine zipper MRG PF05712.13 CCD26370.1 - 1e-44 152.2 4.3 1e-44 152.2 4.3 1.7 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.8 CCD26370.1 - 4.9e-06 26.3 0.1 3.1e-05 23.8 0.0 2.4 2 1 0 2 2 2 1 RNA binding activity-knot of a chromodomain Pet100 PF09803.9 CCD26370.1 - 0.025 15.1 0.3 0.089 13.3 0.3 1.9 1 0 0 1 1 1 0 Pet100 BolA PF01722.18 CCD26371.1 - 2.8e-12 46.7 0.0 7.8e-12 45.3 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein DUF966 PF06136.13 CCD26371.1 - 0.043 13.6 0.3 0.044 13.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4140 PF13600.6 CCD26371.1 - 0.15 12.5 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) EF_assoc_2 PF08356.12 CCD26372.1 - 1.6e-27 95.3 0.1 8.2e-27 93.0 0.0 2.3 2 0 0 2 2 2 1 EF hand associated EF_assoc_1 PF08355.12 CCD26372.1 - 4.3e-27 93.5 0.4 2.2e-26 91.2 0.8 2.1 2 0 0 2 2 2 1 EF hand associated Ras PF00071.22 CCD26372.1 - 2.4e-25 89.0 0.0 6.7e-12 45.3 0.0 2.6 2 1 0 2 2 2 2 Ras family Roc PF08477.13 CCD26372.1 - 1.2e-15 57.8 0.0 1.8e-07 31.4 0.0 3.1 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_7 PF13499.6 CCD26372.1 - 4.6e-07 30.2 0.5 0.073 13.5 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair MMR_HSR1 PF01926.23 CCD26372.1 - 5e-07 29.8 0.0 0.012 15.7 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CCD26372.1 - 7.4e-07 29.4 0.6 0.037 14.1 0.0 3.0 3 0 0 3 3 3 2 Dynamin family EF-hand_1 PF00036.32 CCD26372.1 - 1.3e-06 27.5 12.0 2.9e-05 23.3 0.5 3.6 4 0 0 4 4 3 2 EF hand EF-hand_6 PF13405.6 CCD26372.1 - 4.9e-06 26.0 9.2 3.9e-05 23.3 0.2 3.6 3 0 0 3 3 3 1 EF-hand domain Arf PF00025.21 CCD26372.1 - 2.3e-05 23.9 0.0 0.0016 18.0 0.0 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family EF-hand_8 PF13833.6 CCD26372.1 - 5.8e-05 22.9 1.0 0.017 14.9 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair RsgA_GTPase PF03193.16 CCD26372.1 - 0.00019 21.4 0.4 0.12 12.2 0.0 3.6 3 0 0 3 3 3 1 RsgA GTPase EF-hand_5 PF13202.6 CCD26372.1 - 0.00032 20.0 6.2 0.00073 18.9 1.0 2.9 2 0 0 2 2 2 1 EF hand GTP_EFTU PF00009.27 CCD26372.1 - 0.00042 19.9 0.0 1.2 8.6 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 CCD26372.1 - 0.0038 16.9 0.1 3.1 7.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 CCD26372.1 - 0.0041 17.5 0.0 0.43 11.0 0.0 2.8 3 0 0 3 3 2 1 RNA helicase Septin PF00735.18 CCD26372.1 - 0.0079 15.5 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 1 Septin TniB PF05621.11 CCD26372.1 - 0.023 14.1 0.0 0.47 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 CCD26372.1 - 0.028 14.9 0.0 3.6 8.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 CCD26372.1 - 0.033 13.9 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CCD26372.1 - 0.049 14.2 0.0 0.19 12.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 CCD26372.1 - 0.063 13.7 0.0 3.3 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CCD26372.1 - 0.069 13.4 0.0 1.8 8.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain EF-hand_10 PF14788.6 CCD26372.1 - 0.098 12.5 1.1 1.8 8.5 0.1 2.8 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.9 CCD26372.1 - 0.1 12.9 0.4 20 5.5 0.0 3.3 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Zn_clus PF00172.18 CCD26373.1 - 1.6e-09 37.7 10.6 3.5e-09 36.6 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRP PF06011.12 CCD26374.1 - 8e-155 515.7 36.4 8e-155 515.7 36.4 1.6 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CCD26374.1 - 4.2e-41 140.6 1.7 8.6e-41 139.6 1.7 1.6 1 0 0 1 1 1 1 ML-like domain SR-25 PF10500.9 CCD26374.1 - 0.23 11.0 20.3 0.46 10.1 20.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein STAT_bind PF02864.15 CCD26374.1 - 3.1 8.4 5.7 0.51 10.9 0.6 2.2 2 0 0 2 2 2 0 STAT protein, DNA binding domain Macoilin PF09726.9 CCD26374.1 - 7.9 4.9 18.6 0.12 10.9 4.3 2.1 2 0 0 2 2 2 0 Macoilin family AMP-binding PF00501.28 CCD26375.1 - 7.5e-90 301.5 0.0 9.6e-90 301.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCD26375.1 - 3.2e-24 85.7 0.6 7.4e-23 81.3 0.1 2.8 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CCD26375.1 - 2.7e-16 59.2 2.1 6.6e-16 58.0 2.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Kelch_4 PF13418.6 CCD26376.1 - 1.9e-09 37.4 11.5 7.3e-08 32.3 0.2 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CCD26376.1 - 3.5e-08 33.2 8.1 1.3 9.1 0.0 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 CCD26376.1 - 1.9e-06 27.6 9.1 0.0077 16.2 0.3 6.0 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 CCD26376.1 - 3.9e-06 26.9 10.0 0.007 16.6 0.3 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 CCD26376.1 - 8.6e-06 25.9 0.1 0.058 13.7 0.0 5.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CCD26376.1 - 6.3e-05 22.5 12.2 7.7e-05 22.2 0.2 4.6 5 0 0 5 5 5 1 Kelch motif Alb1 PF09135.11 CCD26377.1 - 9.5e-20 71.4 19.3 3.5e-19 69.6 14.6 2.9 2 1 0 2 2 2 1 Alb1 FAM27 PF15832.5 CCD26377.1 - 0.0021 18.6 1.4 0.0021 18.6 1.4 2.1 2 1 0 2 2 2 1 FAM27 D and E protein family Draxin PF15550.6 CCD26377.1 - 8.6 6.1 11.3 11 5.7 11.3 1.2 1 0 0 1 1 1 0 Draxin zf-C3HC PF07967.13 CCD26378.1 - 1.6e-07 31.5 0.5 4.4e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 C3HC zinc finger-like RdRP PF05183.12 CCD26378.1 - 0.041 12.5 0.6 0.073 11.7 0.2 1.5 2 0 0 2 2 2 0 RNA dependent RNA polymerase SR-25 PF10500.9 CCD26378.1 - 0.29 10.7 5.2 0.45 10.1 5.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ADH_N PF08240.12 CCD26379.1 - 3.1e-30 104.3 1.1 5.6e-30 103.4 1.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCD26379.1 - 9.9e-23 80.5 0.0 1.5e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CCD26379.1 - 2.8e-15 56.4 0.0 3.8e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Pyr_redox PF00070.27 CCD26379.1 - 0.003 18.1 0.2 1.9 9.1 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCD26379.1 - 0.0074 15.6 0.1 0.029 13.6 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CCD26379.1 - 0.041 13.9 0.1 0.11 12.6 0.1 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 CCD26379.1 - 0.079 13.6 0.2 0.36 11.4 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.19 CCD26379.1 - 0.093 12.0 0.3 0.14 11.4 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain ADH_N PF08240.12 CCD26380.1 - 1.6e-33 114.8 2.2 3e-33 114.0 2.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCD26380.1 - 7.6e-21 74.4 0.0 1.2e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CCD26380.1 - 1.6e-08 34.3 0.0 2.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Pyr_redox PF00070.27 CCD26380.1 - 0.0085 16.6 0.1 0.068 13.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CCD26380.1 - 0.013 15.1 0.8 0.026 14.1 0.8 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CCD26380.1 - 0.015 14.5 1.0 0.026 13.8 1.0 1.2 1 0 0 1 1 1 0 FAD binding domain ADH_zinc_N_2 PF13602.6 CCD26380.1 - 0.022 15.8 0.0 0.038 15.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.6 CCD26380.1 - 0.025 13.8 0.8 0.047 12.9 0.8 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 CCD26380.1 - 0.094 13.0 0.1 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 CCD26380.1 - 0.16 12.5 0.0 0.43 11.0 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 CCD26381.1 - 1.2e-77 260.9 6.2 1.6e-77 260.6 6.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CCD26381.1 - 6.9e-48 161.8 0.0 1.4e-47 160.8 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain BTB PF00651.31 CCD26382.1 - 3.6e-19 69.0 3.8 6.5e-10 39.2 0.1 3.0 3 1 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 CCD26382.1 - 9.3e-08 32.5 0.0 2.3e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCD26382.1 - 1.8e-06 28.4 0.0 8.1e-06 26.3 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CCD26382.1 - 0.00073 19.9 0.0 0.0088 16.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 CCD26382.1 - 0.0035 17.7 0.1 0.087 13.4 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CCD26382.1 - 0.043 14.1 0.0 0.28 11.6 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ntox16 PF15523.6 CCD26382.1 - 0.11 12.8 0.7 0.33 11.2 0.7 1.8 1 0 0 1 1 1 0 Novel toxin 16 RRM_1 PF00076.22 CCD26383.1 - 1.2e-12 47.5 0.1 2.1e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCD26383.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CCD26383.1 - 0.019 15.1 0.0 0.027 14.6 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif Nop16 PF09420.10 CCD26384.1 - 2e-70 237.1 18.8 3.4e-70 236.3 18.8 1.3 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 PMI_typeI PF01238.21 CCD26385.1 - 5.8e-154 512.8 0.0 6.6e-154 512.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 CCD26385.1 - 8e-07 29.0 0.0 0.0008 19.3 0.0 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_2 PF07883.11 CCD26385.1 - 0.0057 16.3 0.0 2.4 7.9 0.0 2.6 2 0 0 2 2 2 2 Cupin domain UPF1_Zn_bind PF09416.10 CCD26386.1 - 5.2e-67 224.6 10.2 7.5e-67 224.0 7.3 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 CCD26386.1 - 2.6e-58 197.0 0.0 6.1e-58 195.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CCD26386.1 - 1.4e-49 169.2 4.4 6.7e-27 94.9 0.4 2.5 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 CCD26386.1 - 3.3e-27 94.5 0.0 8.2e-27 93.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 CCD26386.1 - 6.2e-17 61.9 0.2 6.2e-16 58.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCD26386.1 - 3.1e-13 50.3 0.2 6.6e-13 49.2 0.2 1.5 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CCD26386.1 - 5.3e-06 26.2 0.6 0.025 14.1 0.1 3.1 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 CCD26386.1 - 1.2e-05 25.1 0.0 0.26 11.0 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 CCD26386.1 - 2.7e-05 24.2 0.0 8e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CCD26386.1 - 7e-05 22.2 0.1 0.0026 17.1 0.0 3.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 CCD26386.1 - 0.0009 18.5 0.0 0.81 8.8 0.0 2.5 2 0 0 2 2 2 2 PIF1-like helicase Helicase_RecD PF05127.14 CCD26386.1 - 0.0038 17.1 0.0 0.009 15.9 0.0 1.6 1 0 0 1 1 1 1 Helicase PhoH PF02562.16 CCD26386.1 - 0.0074 15.8 0.0 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.29 CCD26386.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase T2SSE PF00437.20 CCD26386.1 - 0.034 13.2 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 CCD26386.1 - 0.073 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF4088 PF13317.6 CCD26386.1 - 0.11 12.1 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) HEM4 PF02602.15 CCD26386.1 - 0.19 11.1 0.1 0.33 10.3 0.1 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD MBR1 PF17058.5 CCD26387.1 - 7.6e-63 212.6 12.3 7.6e-63 212.6 12.3 2.4 2 1 0 2 2 2 1 Mitochondrial biogenesis regulation protein 1 PIR PF00399.19 CCD26388.1 - 1.2e-06 27.9 8.0 4.3e-06 26.1 8.0 2.1 1 0 0 1 1 1 1 Yeast PIR protein repeat DUF3530 PF12048.8 CCD26388.1 - 0.057 12.8 6.5 0.078 12.4 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Peptidase_A22B PF04258.13 CCD26389.1 - 1.7e-63 214.8 8.1 1.7e-63 214.8 8.1 1.5 2 0 0 2 2 2 1 Signal peptide peptidase ADH_N PF08240.12 CCD26390.1 - 2.1e-30 104.8 0.6 4.4e-30 103.8 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCD26390.1 - 7.8e-26 90.6 0.4 1.3e-25 89.9 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCD26390.1 - 1.3e-05 26.2 0.0 2.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 CCD26390.1 - 0.02 14.4 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.21 CCD26390.1 - 0.041 13.2 0.3 0.11 11.7 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Aminotran_1_2 PF00155.21 CCD26392.1 - 2.1e-30 106.1 0.0 2.7e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Macro_2 PF14519.6 CCD26393.1 - 2.2e-131 437.3 0.1 2.6e-131 437.1 0.1 1.0 1 0 0 1 1 1 1 Macro-like domain MFS_1 PF07690.16 CCD26394.1 - 2.7e-37 128.5 37.3 1.8e-31 109.4 15.0 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 CCD26394.1 - 5.9e-14 51.8 8.1 5.9e-14 51.8 8.1 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter Peptidase_M41 PF01434.18 CCD26395.1 - 3.1e-65 219.6 0.4 8.4e-65 218.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 CCD26395.1 - 4.1e-42 143.7 0.0 8.4e-42 142.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCD26395.1 - 6.5e-13 48.3 0.0 2e-12 46.7 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 CCD26395.1 - 1.1e-09 38.6 0.6 2.8e-09 37.3 0.6 1.7 1 0 0 1 1 1 1 FtsH Extracellular RuvB_N PF05496.12 CCD26395.1 - 0.0021 17.8 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CCD26395.1 - 0.0021 18.1 0.0 0.0085 16.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 CCD26395.1 - 0.0035 17.8 0.4 0.01 16.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 CCD26395.1 - 0.0043 16.3 0.0 0.0086 15.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 CCD26395.1 - 0.0044 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CCD26395.1 - 0.0046 17.4 2.1 0.055 13.9 0.1 3.1 3 1 1 4 4 3 1 AAA ATPase domain AAA_33 PF13671.6 CCD26395.1 - 0.0066 16.6 0.6 0.3 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CCD26395.1 - 0.021 15.1 1.1 1 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CCD26395.1 - 0.03 14.6 0.1 0.67 10.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CCD26395.1 - 0.034 13.9 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein pRN1_helical PF13010.6 CCD26395.1 - 0.04 13.9 5.8 0.11 12.4 5.8 1.7 1 0 0 1 1 1 0 Primase helical domain TcdB_N PF12918.7 CCD26395.1 - 0.097 13.0 0.5 0.36 11.2 0.5 2.0 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain mRNA_stabil PF13929.6 CCD26396.1 - 1.4e-96 322.8 10.8 1.4e-96 322.8 10.8 1.5 2 0 0 2 2 2 1 mRNA stabilisation RsfS PF02410.15 CCD26396.1 - 2.3e-14 53.6 0.2 6.1e-14 52.3 0.2 1.8 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation DUF5127 PF17168.4 CCD26396.1 - 0.073 12.8 1.4 0.071 12.9 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5127) Cnd1_N PF12922.7 CCD26396.1 - 7.1 6.4 8.7 0.61 9.9 1.0 2.7 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term UTP15_C PF09384.10 CCD26398.1 - 8.2e-44 148.8 0.5 1.4e-43 148.1 0.5 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CCD26398.1 - 6.3e-19 68.0 5.5 0.002 18.9 0.2 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD26398.1 - 5.9e-07 29.7 0.0 0.037 14.3 0.0 5.0 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CCD26398.1 - 0.004 17.2 0.1 6.5 6.8 0.0 3.8 3 3 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 CCD26399.1 - 7.8e-16 58.2 21.5 0.026 15.4 0.0 10.3 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD26399.1 - 4.2e-09 36.6 6.5 2.5 8.5 0.0 6.7 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCD26399.1 - 8.1e-09 35.6 0.7 0.003 17.5 0.0 3.9 2 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A FAM131 PF15010.6 CCD26399.1 - 0.042 13.8 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative cell signalling WD40_like PF17005.5 CCD26399.1 - 0.046 13.1 7.0 0.14 11.5 5.4 2.4 1 1 2 3 3 3 0 WD40-like domain CRC_subunit PF08624.10 CCD26400.1 - 3.6e-50 169.9 0.1 7.6e-50 168.9 0.1 1.6 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit NAD_binding_10 PF13460.6 CCD26401.1 - 2.4e-50 171.0 0.0 2.8e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CCD26401.1 - 1.1e-11 44.7 0.2 2.1e-11 43.8 0.2 1.4 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 CCD26401.1 - 1.3e-09 37.5 0.7 1.9e-09 37.0 0.7 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CCD26401.1 - 8.1e-06 25.5 0.2 2.2e-05 24.0 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 CCD26401.1 - 8.7e-06 26.2 0.1 1.5e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CCD26401.1 - 2.4e-05 24.4 0.1 4.1e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 CCD26401.1 - 0.00027 21.2 0.2 0.00049 20.4 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 CCD26401.1 - 0.001 19.2 0.3 0.0014 18.7 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CCD26401.1 - 0.0054 17.3 1.1 0.0084 16.7 0.2 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 CCD26401.1 - 0.032 15.1 0.1 0.06 14.2 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold BAF1_ABF1 PF04684.13 CCD26402.1 - 1.6e-201 671.3 93.2 2.6e-200 667.3 93.2 2.4 1 1 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.15 CCD26402.1 - 0.057 13.4 0.6 0.13 12.3 0.6 1.5 1 0 0 1 1 1 0 MuDR family transposase XPG_N PF00752.17 CCD26403.1 - 1.3e-38 131.6 0.0 2.7e-38 130.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CCD26403.1 - 2.9e-30 104.5 0.0 7.4e-30 103.2 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CCD26403.1 - 1.1e-06 29.2 0.8 1.3e-05 25.7 0.0 2.7 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 CCD26403.1 - 0.015 15.2 0.1 0.11 12.3 0.1 2.2 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain HHH_5 PF14520.6 CCD26403.1 - 0.031 14.9 0.2 0.2 12.3 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_2 PF12826.7 CCD26403.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Aldose_epim PF01263.20 CCD26404.1 - 2.2e-49 168.4 0.4 2.6e-49 168.2 0.4 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase zf-MYND PF01753.18 CCD26405.1 - 1.1e-06 28.6 22.3 2.8e-06 27.3 22.3 1.7 1 1 0 1 1 1 1 MYND finger Arm PF00514.23 CCD26405.1 - 0.011 15.8 0.0 5.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF1866 PF08952.11 CCD26405.1 - 0.15 11.9 0.1 0.42 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) Prenyltransf PF01255.19 CCD26406.1 - 1.6e-63 214.3 0.1 2.1e-63 213.9 0.1 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase SHP PF03579.13 CCD26406.1 - 3.2 7.8 6.1 0.36 10.8 0.7 2.2 2 1 1 3 3 3 0 Small hydrophobic protein WD40 PF00400.32 CCD26407.1 - 2.2e-12 47.3 21.8 0.00019 22.2 0.1 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD26407.1 - 7.4e-08 32.6 1.5 0.39 11.1 0.1 5.4 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain TF_Zn_Ribbon PF08271.12 CCD26407.1 - 0.0015 18.0 2.0 0.0015 18.0 2.0 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding BBS2_Mid PF14783.6 CCD26407.1 - 0.036 14.1 0.6 7 6.7 0.0 3.6 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Lar_restr_allev PF14354.6 CCD26407.1 - 0.12 12.7 0.3 0.31 11.4 0.3 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar HNH PF01844.23 CCD26407.1 - 5.6 7.2 6.3 30 4.9 0.1 3.1 3 0 0 3 3 3 0 HNH endonuclease Pkinase PF00069.25 CCD26408.1 - 4.9e-69 232.6 0.0 8.4e-69 231.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26408.1 - 2.9e-31 108.7 0.0 4.3e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CCD26408.1 - 2.1e-10 41.1 0.4 5.4e-10 39.8 0.4 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CCD26408.1 - 2.3e-05 23.5 0.1 4.9e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 CCD26408.1 - 0.013 15.2 0.0 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CCD26408.1 - 0.013 14.9 0.0 0.033 13.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CCD26408.1 - 0.055 12.8 0.2 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SelP_N PF04592.14 CCD26408.1 - 2.7 7.3 10.0 6.4 6.1 10.0 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 CCD26408.1 - 4.5 5.7 13.7 6.6 5.2 13.7 1.1 1 0 0 1 1 1 0 Macoilin family PGM_PMM_I PF02878.16 CCD26409.1 - 9.6e-37 125.8 0.6 6.4e-36 123.1 0.2 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CCD26409.1 - 1.6e-24 86.3 0.0 2.9e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CCD26409.1 - 3.3e-14 53.4 0.0 6.9e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CCD26409.1 - 4e-06 26.9 0.0 8.7e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ku PF02735.16 CCD26410.1 - 2.8e-37 128.4 0.4 9.6e-37 126.7 0.1 1.9 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CCD26410.1 - 2.1e-17 63.6 0.3 3.5e-17 62.9 0.3 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain TP6A_N PF04406.14 CCD26411.1 - 2.3e-13 49.9 0.6 6.1e-13 48.5 0.6 1.8 1 0 0 1 1 1 1 Type IIB DNA topoisomerase TPP_enzyme_N PF02776.18 CCD26412.1 - 8.3e-55 185.0 0.1 4.8e-54 182.5 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CCD26412.1 - 7.5e-50 168.7 0.0 4.9e-49 166.0 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCD26412.1 - 9.6e-41 138.7 0.3 2.6e-40 137.3 0.2 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 CCD26412.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Aldedh PF00171.22 CCD26413.1 - 1.9e-77 260.7 0.0 2.3e-77 260.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF5104 PF17117.5 CCD26413.1 - 0.021 15.3 0.5 6.4 7.3 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5104) Cys_Met_Meta_PP PF01053.20 CCD26414.1 - 1e-144 481.8 0.0 1.1e-144 481.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 CCD26414.1 - 2.6e-05 22.9 0.0 3.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 CCD26414.1 - 0.00026 20.3 0.1 0.00037 19.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CCD26414.1 - 0.015 14.3 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Ribosomal_S19 PF00203.21 CCD26415.1 - 1e-33 115.1 0.1 3.6e-33 113.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S19 FliH PF02108.16 CCD26415.1 - 0.091 12.8 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH Sds3 PF08598.11 CCD26416.1 - 4.5e-47 160.9 2.8 4.5e-47 160.9 2.8 3.4 2 1 0 2 2 2 1 Sds3-like Gpr1_Fun34_YaaH PF01184.19 CCD26417.1 - 8.7e-91 303.1 13.1 1e-90 302.9 13.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family SPW PF03779.14 CCD26417.1 - 0.036 13.7 2.2 0.62 9.7 0.6 2.6 2 0 0 2 2 2 0 SPW repeat SNARE PF05739.19 CCD26418.1 - 9.5e-09 35.1 0.1 2e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 SNARE domain CAML PF14963.6 CCD26418.1 - 0.32 11.1 4.2 0.49 10.5 4.2 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand UPF0515 PF15135.6 CCD26418.1 - 0.8 9.0 3.8 0.29 10.4 0.7 1.7 1 1 1 2 2 2 0 Uncharacterised protein UPF0515 HhH-GPD PF00730.25 CCD26419.1 - 8.1e-23 80.9 0.1 2e-22 79.7 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CCD26419.1 - 2.3e-06 27.2 0.0 1e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif Spot_14 PF07084.12 CCD26419.1 - 0.061 13.5 0.1 0.061 13.5 0.1 1.8 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 HHH_5 PF14520.6 CCD26419.1 - 0.13 12.9 0.0 0.69 10.6 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain HEAT PF02985.22 CCD26420.1 - 3.2e-40 132.7 13.5 0.00059 19.9 0.1 13.4 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.6 CCD26420.1 - 4.6e-28 97.4 1.1 2.9e-09 37.2 0.0 7.8 3 3 4 7 7 7 6 HEAT repeats Vac14_Fab1_bd PF12755.7 CCD26420.1 - 1.8e-14 54.1 4.0 0.00065 20.2 0.0 8.5 4 2 5 9 9 9 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CCD26420.1 - 8.6e-07 29.3 6.4 1 9.9 0.1 8.1 10 0 0 10 10 10 1 HEAT-like repeat Cnd1 PF12717.7 CCD26420.1 - 3.3e-06 27.3 13.2 0.0021 18.1 1.9 5.4 2 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 M11L PF11099.8 CCD26420.1 - 0.00025 21.3 3.0 0.26 11.6 0.2 3.1 2 1 0 2 2 2 2 Apoptosis regulator M11L like API5 PF05918.11 CCD26420.1 - 0.00061 18.7 0.8 0.00061 18.7 0.8 4.3 5 1 1 6 6 6 1 Apoptosis inhibitory protein 5 (API5) TAF6_C PF07571.13 CCD26420.1 - 0.023 15.0 0.0 1.8 9.0 0.0 3.2 3 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain GatB_Yqey PF02637.18 CCD26420.1 - 0.058 13.3 0.6 10 6.0 0.0 2.6 2 0 0 2 2 2 0 GatB domain Arm PF00514.23 CCD26420.1 - 0.23 11.6 4.0 12 6.1 0.1 4.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 CCD26421.1 - 3.7e-63 213.4 0.1 8.1e-63 212.2 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26421.1 - 2.5e-23 82.7 0.0 4.1e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD26421.1 - 3.7e-09 36.3 0.0 7.1e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCD26421.1 - 0.0051 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCD26421.1 - 0.0088 14.9 3.2 0.013 14.2 0.0 2.7 2 0 0 2 2 2 1 Fungal protein kinase PAS_9 PF13426.7 CCD26421.1 - 0.024 14.9 0.0 0.49 10.7 0.0 2.9 2 0 0 2 2 2 0 PAS domain Kdo PF06293.14 CCD26421.1 - 0.037 13.4 0.1 0.075 12.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CCD26421.1 - 0.038 13.6 0.1 0.093 12.3 0.1 1.6 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CCD26421.1 - 0.088 12.4 1.3 0.31 10.6 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 EI24 PF07264.11 CCD26422.1 - 4.6e-06 27.0 12.8 6.6e-06 26.5 12.8 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) YdfA_immunity PF12127.8 CCD26422.1 - 0.085 11.9 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 SigmaW regulon antibacterial PRR20 PF15708.5 CCD26422.1 - 0.22 11.4 0.1 0.35 10.8 0.1 1.2 1 0 0 1 1 1 0 Proline-rich protein family 20 DUF3899 PF13038.6 CCD26422.1 - 0.74 10.4 8.6 0.1 13.1 1.2 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF3899) Gal11_ABD1 PF18535.1 CCD26423.1 - 4.6e-39 132.4 21.0 4.6e-39 132.4 21.0 8.4 5 3 3 8 8 8 1 Gal11 activator-binding domain (ABD1) Med15_fungi PF05397.12 CCD26423.1 - 5.5e-33 113.6 3.2 5.5e-33 113.6 3.2 7.2 3 2 4 7 7 7 1 Mediator complex subunit 15 KIX_2 PF16987.5 CCD26423.1 - 5.8e-18 64.7 1.7 5.8e-18 64.7 1.7 4.5 4 0 0 4 4 4 1 KIX domain SNF2_N PF00176.23 CCD26424.1 - 1.9e-55 188.0 0.3 1.9e-55 188.0 0.3 2.0 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCD26424.1 - 3.9e-20 72.3 0.1 1.6e-16 60.6 0.1 3.3 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 CCD26424.1 - 6.5e-12 45.8 0.1 3.3e-11 43.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CCD26424.1 - 2.5e-05 23.6 0.2 7.1e-05 22.1 0.2 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ER-remodelling PF14755.6 CCD26424.1 - 0.2 11.9 3.0 0.56 10.5 3.0 1.7 1 0 0 1 1 1 0 Intracellular membrane remodeller Anillin_N PF16018.5 CCD26424.1 - 0.94 10.1 6.3 4.7 7.9 0.1 3.9 2 1 1 3 3 3 0 Anillin N-terminus RCC1 PF00415.18 CCD26425.1 - 1e-12 48.5 5.1 0.8 10.4 0.0 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CCD26425.1 - 3.3e-10 39.5 20.6 1.3e-05 24.8 1.3 5.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Exo_endo_phos PF03372.23 CCD26426.1 - 7.5e-21 74.7 0.0 4.8e-20 72.1 0.0 2.3 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 CCD26426.1 - 2.6e-07 30.9 13.3 5.7e-05 23.4 3.9 5.9 7 1 1 8 8 8 2 Leucine Rich repeats (2 copies) Nucleoside_tran PF01733.18 CCD26427.1 - 6e-58 196.7 24.2 1.6e-42 146.0 7.7 2.6 2 1 1 3 3 3 2 Nucleoside transporter PMT PF02366.18 CCD26428.1 - 3.1e-96 321.7 16.8 3.1e-96 321.7 16.8 1.8 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCD26428.1 - 2.6e-60 203.5 10.4 2.6e-60 203.5 10.4 2.6 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCD26428.1 - 1.7e-20 73.7 0.2 3.3e-20 72.7 0.2 1.4 1 0 0 1 1 1 1 MIR domain DUF2723 PF11028.8 CCD26428.1 - 0.045 13.7 9.3 0.24 11.3 2.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) RasGEF PF00617.19 CCD26429.1 - 5.1e-41 140.8 0.8 5.1e-41 140.8 0.8 2.5 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 CCD26429.1 - 5.1e-12 46.0 0.6 5.1e-12 46.0 0.6 3.3 3 0 0 3 3 3 1 RasGEF N-terminal motif PhoLip_ATPase_C PF16212.5 CCD26430.1 - 6.7e-81 271.7 26.8 6.7e-81 271.7 26.8 3.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCD26430.1 - 5.1e-25 87.0 5.5 1.4e-24 85.6 5.5 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CCD26430.1 - 7.3e-11 42.7 0.4 0.00015 22.1 0.1 3.3 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCD26430.1 - 5e-10 39.3 0.0 3.8e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CCD26430.1 - 1e-06 28.4 0.1 2.3e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CCD26430.1 - 0.00017 21.4 1.1 0.032 14.0 0.1 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Saw1 PF11561.8 CCD26431.1 - 1.8e-87 292.9 9.4 2.1e-87 292.8 9.4 1.0 1 0 0 1 1 1 1 Single strand annealing-weakened 1 Hph PF13694.6 CCD26432.1 - 6e-10 39.7 16.1 6e-10 39.7 16.1 4.7 2 1 0 3 3 3 1 Sec63/Sec62 complex-interacting family Trns_repr_metal PF02583.17 CCD26432.1 - 0.23 11.8 0.9 0.47 10.9 0.1 1.9 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor Myosin_head PF00063.21 CCD26433.1 - 1.4e-268 892.7 17.0 1.4e-268 892.7 17.0 2.5 3 0 0 3 3 3 1 Myosin head (motor domain) DIL PF01843.19 CCD26433.1 - 8.9e-19 67.7 2.1 8.9e-19 67.7 2.1 3.7 4 0 0 4 4 4 1 DIL domain IQ PF00612.27 CCD26433.1 - 0.00011 21.6 18.0 1.1 9.3 1.2 6.5 6 0 0 6 6 6 1 IQ calmodulin-binding motif Myosin_N PF02736.19 CCD26433.1 - 0.0044 16.8 0.5 0.012 15.5 0.1 2.1 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain RsgA_GTPase PF03193.16 CCD26433.1 - 0.0055 16.6 1.2 0.021 14.7 0.0 2.6 2 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CCD26433.1 - 0.0064 16.8 2.7 0.027 14.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 CCD26433.1 - 0.019 14.0 0.0 0.05 12.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 CCD26433.1 - 0.021 15.4 0.1 0.021 15.4 0.1 3.1 2 1 0 2 2 1 0 ABC transporter CbiA PF01656.23 CCD26433.1 - 0.028 14.5 0.0 0.18 11.8 0.0 2.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 CCD26433.1 - 0.043 14.2 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 CCD26433.1 - 0.05 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2281 PF10047.9 CCD26433.1 - 0.12 13.1 0.4 1.4 9.7 0.0 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF2281) vATP-synt_E PF01991.18 CCD26434.1 - 2.4e-61 206.6 16.4 2.8e-61 206.4 16.4 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit tRNA-synt_2e PF02091.15 CCD26434.1 - 0.059 12.6 1.5 0.075 12.3 1.5 1.2 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit Phlebovirus_NSM PF07246.11 CCD26434.1 - 0.13 11.6 10.4 0.11 11.9 9.0 1.4 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4162 PF13732.6 CCD26434.1 - 0.13 13.0 10.2 0.063 14.0 3.4 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4162) Folliculin PF11704.8 CCD26434.1 - 0.54 10.1 3.5 0.83 9.5 3.5 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport EMP24_GP25L PF01105.24 CCD26436.1 - 6.3e-35 120.8 0.8 6.3e-35 120.8 0.8 1.4 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD Imm64 PF15600.6 CCD26436.1 - 0.0023 17.7 0.4 0.0031 17.2 0.4 1.2 1 0 0 1 1 1 1 Immunity protein 64 FUN14 PF04930.15 CCD26437.1 - 0.0021 18.4 1.3 0.0021 18.4 1.3 1.8 2 0 0 2 2 2 1 FUN14 family Peptidase_A2B PF12384.8 CCD26438.1 - 0.029 13.9 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase MCR_alpha_N PF02745.15 CCD26438.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.5 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain Spo7 PF03907.13 CCD26439.1 - 1.2e-71 240.7 4.8 1.8e-71 240.1 4.8 1.3 1 0 0 1 1 1 1 Spo7-like protein DUF2208 PF09973.9 CCD26439.1 - 0.0012 18.5 0.4 0.0019 17.8 0.4 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) DUF4538 PF15061.6 CCD26439.1 - 0.17 11.6 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) MDM10 PF12519.8 CCD26440.1 - 2.3e-136 455.3 27.1 2.8e-136 455.1 27.1 1.0 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 DUF999 PF06198.11 CCD26440.1 - 2.6 8.0 6.9 2.3 8.2 0.5 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF999) GCR1_C PF12550.8 CCD26442.1 - 3.4e-22 78.6 0.9 7.8e-22 77.4 0.9 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF4061 PF13270.6 CCD26442.1 - 0.64 10.4 7.5 0.081 13.3 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) SRAP PF02586.14 CCD26443.1 - 1.6e-63 214.2 0.1 2.2e-63 213.8 0.1 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) TPR_12 PF13424.6 CCD26444.1 - 0.001 19.3 3.1 0.069 13.4 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3498 PF12004.8 CCD26444.1 - 0.006 15.8 0.1 0.0086 15.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3498) SNAP PF14938.6 CCD26444.1 - 0.007 15.8 6.4 0.37 10.2 1.0 2.2 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP MIT PF04212.18 CCD26444.1 - 0.1 12.7 2.7 9.6 6.4 0.0 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF1759 PF03564.15 CCD26444.1 - 0.4 10.6 4.7 20 5.1 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) WD40 PF00400.32 CCD26445.1 - 6.3e-44 147.1 10.8 2.4e-07 31.3 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD26445.1 - 8.4e-10 38.8 1.2 0.033 14.5 0.0 4.8 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCD26445.1 - 4.8e-06 25.5 5.2 0.0096 14.6 0.1 4.5 2 1 2 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CCD26445.1 - 7.5e-06 25.1 0.4 0.42 9.5 0.0 4.0 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CCD26445.1 - 0.00013 21.9 0.5 0.019 14.9 0.1 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CCD26445.1 - 0.045 13.7 0.0 17 5.5 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat KOW PF00467.29 CCD26445.1 - 0.099 12.6 0.0 0.58 10.2 0.0 2.2 2 0 0 2 2 2 0 KOW motif Nucleoporin_N PF08801.11 CCD26445.1 - 0.11 11.3 0.7 2.6 6.7 0.2 2.9 1 1 2 3 3 3 0 Nup133 N terminal like Spc24 PF08286.11 CCD26446.1 - 3.6e-24 85.0 4.2 3.6e-24 85.0 4.2 3.1 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Tup_N PF08581.10 CCD26446.1 - 0.00012 22.3 5.2 0.0017 18.6 0.5 2.6 2 0 0 2 2 2 1 Tup N-terminal Spc7 PF08317.11 CCD26446.1 - 0.0038 16.2 11.6 0.0086 15.0 11.6 1.6 1 1 0 1 1 1 1 Spc7 kinetochore protein Allexi_40kDa PF05549.11 CCD26446.1 - 0.0053 16.3 6.2 0.008 15.7 6.2 1.2 1 0 0 1 1 1 1 Allexivirus 40kDa protein HBM PF16591.5 CCD26446.1 - 0.0077 15.7 2.8 0.014 14.9 2.8 1.4 1 0 0 1 1 1 1 Helical bimodular sensor domain BRE1 PF08647.11 CCD26446.1 - 0.008 16.2 11.5 0.12 12.4 0.8 2.9 1 1 1 2 2 2 1 BRE1 E3 ubiquitin ligase GrpE PF01025.19 CCD26446.1 - 0.024 14.3 5.4 0.041 13.5 5.4 1.3 1 0 0 1 1 1 0 GrpE LemA PF04011.12 CCD26446.1 - 0.038 13.9 2.0 0.094 12.6 2.0 1.6 1 1 0 1 1 1 0 LemA family Lzipper-MIP1 PF14389.6 CCD26446.1 - 0.063 13.6 4.1 0.16 12.3 4.1 1.8 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 SKA2 PF16740.5 CCD26446.1 - 0.068 13.0 4.7 0.1 12.4 2.2 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 TPR_MLP1_2 PF07926.12 CCD26446.1 - 0.21 11.6 9.1 0.46 10.5 6.1 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 CCD26446.1 - 0.38 10.8 8.9 0.71 9.9 8.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 CCD26446.1 - 0.38 11.0 13.9 1.9 8.7 13.9 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Nbl1_Borealin_N PF10444.9 CCD26446.1 - 0.49 10.1 3.3 0.66 9.6 0.6 2.5 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal Fez1 PF06818.15 CCD26446.1 - 0.78 10.2 9.2 1.6 9.1 9.2 1.5 1 1 0 1 1 1 0 Fez1 DUF4208 PF13907.6 CCD26446.1 - 0.81 10.2 5.2 1.4 9.4 4.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) TMPIT PF07851.13 CCD26446.1 - 0.85 8.8 6.1 1.2 8.3 6.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3552 PF12072.8 CCD26446.1 - 0.97 8.8 10.3 1.4 8.2 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1664 PF07889.12 CCD26446.1 - 1.2 9.2 8.1 9.8 6.2 8.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Lectin_N PF03954.14 CCD26446.1 - 1.4 8.7 6.3 2.8 7.7 6.2 1.5 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain HIP1_clath_bdg PF16515.5 CCD26446.1 - 1.8 9.2 10.0 1.5 9.5 7.3 2.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YrzO PF14142.6 CCD26446.1 - 1.9 8.5 4.9 13 5.8 0.3 2.9 2 1 1 3 3 3 0 YrzO-like protein ACCA PF03255.14 CCD26446.1 - 2.7 7.9 7.1 9.3 6.1 0.6 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Synaptobrevin PF00957.21 CCD26446.1 - 3.3 7.6 7.7 8.6 6.2 0.8 2.6 2 1 0 2 2 2 0 Synaptobrevin Fib_alpha PF08702.10 CCD26446.1 - 4.2 7.5 11.5 3.9 7.6 8.0 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family zf-C3HC4_3 PF13920.6 CCD26447.1 - 6.7e-10 38.7 12.2 6.7e-10 38.7 12.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) VESA1_N PF12785.7 CCD26447.1 - 0.0007 18.7 9.5 0.0014 17.7 9.5 1.4 1 0 0 1 1 1 1 Variant erythrocyte surface antigen-1 Prok-RING_4 PF14447.6 CCD26447.1 - 0.015 15.1 11.1 0.015 15.1 11.1 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 AICARFT_IMPCHas PF01808.18 CCD26448.1 - 1.1e-93 313.9 0.0 1.6e-93 313.4 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CCD26448.1 - 2.6e-24 85.2 0.3 1.6e-23 82.7 0.0 2.1 2 0 0 2 2 2 1 MGS-like domain CAF1C_H4-bd PF12265.8 CCD26449.1 - 3.6e-16 59.2 0.1 8.7e-16 57.9 0.1 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CCD26449.1 - 6.4e-10 39.5 7.4 0.0097 16.7 0.0 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD26449.1 - 3.9e-08 33.5 0.9 0.0016 18.7 0.1 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain HAD_2 PF13419.6 CCD26450.1 - 5.2e-10 39.7 0.0 8.3e-10 39.0 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCD26450.1 - 9.4e-10 39.1 0.0 1.3e-09 38.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCD26450.1 - 1.9e-07 31.0 0.0 3.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like MOZ_SAS PF01853.18 CCD26452.1 - 1.9e-59 200.3 0.3 3.2e-59 199.6 0.3 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CCD26452.1 - 4.7e-09 35.7 3.6 8.7e-07 28.5 1.6 2.6 2 0 0 2 2 2 2 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CCD26452.1 - 0.026 14.9 0.0 0.054 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TLP-20 PF06088.11 CCD26452.1 - 0.038 13.9 5.6 0.15 12.0 2.7 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Ribosomal_60s PF00428.19 CCD26452.1 - 0.18 12.4 5.4 0.31 11.6 5.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4746 PF15928.5 CCD26452.1 - 2.6 7.4 8.9 3.8 6.8 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Myc_N PF01056.18 CCD26452.1 - 4.1 7.2 7.3 7.6 6.3 7.3 1.4 1 0 0 1 1 1 0 Myc amino-terminal region TT_ORF1 PF02956.14 CCD26453.1 - 2.5 6.7 11.9 3.1 6.4 11.3 1.3 1 1 0 1 1 1 0 TT viral orf 1 MIF4G_like PF09088.11 CCD26454.1 - 1.2e-55 188.2 1.5 3.8e-55 186.6 0.7 2.3 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.11 CCD26454.1 - 1.1e-53 182.4 2.6 2.2e-51 174.9 2.6 3.0 1 1 0 1 1 1 1 MIF4G like MIF4G PF02854.19 CCD26454.1 - 8.8e-14 51.6 6.4 8.8e-14 51.6 6.4 2.7 3 0 0 3 3 3 1 MIF4G domain Pkr1 PF08636.10 CCD26457.1 - 1.4e-30 105.2 11.1 1.8e-30 104.8 11.1 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Halogen_Hydrol PF10112.9 CCD26457.1 - 0.035 14.1 0.1 0.041 13.9 0.1 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4191 PF13829.6 CCD26457.1 - 0.045 13.1 0.8 0.059 12.7 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Kei1 PF08552.11 CCD26457.1 - 0.055 13.4 1.9 0.15 11.9 1.9 1.8 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4834 PF16118.5 CCD26457.1 - 0.085 13.8 1.8 0.19 12.7 1.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) NFACT-R_1 PF05670.13 CCD26459.1 - 1.5e-33 115.7 0.1 2.5e-33 115.0 0.1 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 CCD26459.1 - 0.21 11.5 5.1 0.96 9.4 5.1 2.0 1 1 0 1 1 1 0 NFACT protein C-terminal domain Meiotic_rec114 PF03525.14 CCD26460.1 - 4.7e-08 32.4 9.8 1.4e-07 30.8 9.8 2.0 1 1 0 1 1 1 1 Meiotic recombination protein rec114 DUF1917 PF08939.10 CCD26460.1 - 0.1 12.5 3.4 0.18 11.7 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) CLTH PF10607.9 CCD26462.1 - 8.9e-24 84.1 10.0 8.9e-24 84.1 10.0 2.8 3 0 0 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain NOP5NT PF08156.13 CCD26462.1 - 0.0059 17.0 0.3 0.031 14.7 0.3 2.3 1 0 0 1 1 1 1 NOP5NT (NUC127) domain ALMT PF11744.8 CCD26462.1 - 4.3 6.0 9.8 11 4.7 9.8 1.7 1 0 0 1 1 1 0 Aluminium activated malate transporter GATA PF00320.27 CCD26463.1 - 4e-16 58.3 3.3 8.9e-16 57.2 3.3 1.7 1 0 0 1 1 1 1 GATA zinc finger DRMBL PF07522.14 CCD26464.1 - 1.7e-23 82.9 0.1 1.7e-23 82.9 0.1 3.0 3 1 0 3 3 3 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 CCD26464.1 - 5.3e-05 22.8 0.0 9.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Arf PF00025.21 CCD26465.1 - 2.7e-37 127.9 0.5 7.4e-34 116.7 0.6 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 CCD26465.1 - 4.1e-15 55.8 5.6 1.4e-08 34.4 0.1 2.9 2 1 1 3 3 3 2 G-protein alpha subunit Roc PF08477.13 CCD26465.1 - 1.8e-11 44.3 0.1 1.4e-10 41.4 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CCD26465.1 - 7e-07 29.3 0.0 1e-06 28.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 CCD26465.1 - 1.8e-06 27.7 0.0 0.00014 21.6 0.0 2.4 2 0 0 2 2 2 1 Ras family GTP_EFTU PF00009.27 CCD26465.1 - 1.4e-05 24.7 0.0 0.0087 15.6 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CCD26465.1 - 3.9e-05 23.1 0.0 0.00046 19.6 0.0 2.2 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CCD26465.1 - 0.0079 16.1 0.1 4.8 7.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CCD26465.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CCD26465.1 - 0.02 14.4 0.3 0.87 9.1 0.0 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B DAP3 PF10236.9 CCD26465.1 - 0.023 13.9 0.1 0.029 13.5 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Bd3614-deam PF14439.6 CCD26465.1 - 0.094 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase AAA_29 PF13555.6 CCD26465.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.25 CCD26466.1 - 2.2e-57 194.4 0.1 3.6e-57 193.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26466.1 - 4.4e-24 85.2 0.0 8.1e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCD26466.1 - 0.0074 16.2 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCD26466.1 - 1.3 7.7 9.8 16 4.1 9.8 2.7 1 1 0 1 1 1 0 Fungal protein kinase CCDC32 PF14989.6 CCD26466.1 - 3.3 7.7 9.2 0.35 10.9 2.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing 32 Choline_kinase PF01633.20 CCD26466.1 - 3.8 7.0 11.1 0.052 13.1 0.8 2.6 3 0 0 3 3 3 0 Choline/ethanolamine kinase ADH_N PF08240.12 CCD26467.1 - 2.5e-27 94.9 5.1 4.8e-27 94.0 5.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCD26467.1 - 1.5e-18 67.0 0.0 3.4e-18 65.9 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CCD26467.1 - 2.3e-05 23.8 0.3 4.1e-05 23.0 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CCD26467.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.12 CCD26468.1 - 1.3e-28 99.1 4.1 2.5e-28 98.1 4.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCD26468.1 - 8e-18 64.7 0.0 1.5e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CCD26468.1 - 0.00022 20.6 0.1 0.00046 19.6 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CCD26468.1 - 0.0097 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Aldo_ket_red PF00248.21 CCD26469.1 - 7.4e-64 215.7 0.0 8.5e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-C3HC4_3 PF13920.6 CCD26470.1 - 0.11 12.4 5.9 0.47 10.4 3.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L13e PF01294.18 CCD26471.1 - 2.3e-67 226.3 4.3 3.4e-67 225.8 4.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_S9 PF00380.19 CCD26472.1 - 2.9e-32 111.7 0.1 3.3e-32 111.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Imm59 PF15597.6 CCD26473.1 - 0.075 13.5 3.8 0.2 12.1 3.8 1.8 1 0 0 1 1 1 0 Immunity protein 59 Pyr_redox_2 PF07992.14 CCD26474.1 - 9.6e-48 162.9 0.0 1.2e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCD26474.1 - 5e-11 43.0 0.1 2.2e-09 37.7 0.4 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCD26474.1 - 0.00095 18.5 0.7 1.4 8.1 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 4F5 PF04419.14 CCD26475.1 - 1.2e-09 38.9 12.0 1.2e-09 38.9 12.0 2.2 2 0 0 2 2 2 1 4F5 protein family Vac_Fusion PF02346.16 CCD26475.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.4 1 1 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 WD40 PF00400.32 CCD26476.1 - 1.1e-20 73.5 4.1 5.7e-05 23.8 0.6 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD26476.1 - 1.1e-06 28.9 0.2 2.7 8.4 0.0 5.0 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCD26476.1 - 0.00017 21.5 0.5 0.84 9.5 0.1 3.3 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A SoxD PF04267.12 CCD26476.1 - 0.12 12.5 0.0 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Sarcosine oxidase, delta subunit family RRN3 PF05327.11 CCD26477.1 - 0.028 13.0 8.6 0.028 13.0 8.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 CCD26477.1 - 0.051 11.9 8.8 0.056 11.7 8.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 CCD26477.1 - 1.6 7.8 18.0 1.8 7.6 18.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 CCD26477.1 - 2.5 7.3 13.3 4.3 6.6 13.3 1.4 1 0 0 1 1 1 0 NOA36 protein PI3K_1B_p101 PF10486.9 CCD26477.1 - 5.9 4.5 8.5 6.7 4.4 8.5 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Vfa1 PF08432.10 CCD26477.1 - 6 7.2 14.4 2.4 8.5 11.9 1.6 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 CCD26477.1 - 6 4.9 21.7 8.6 4.4 21.7 1.3 1 0 0 1 1 1 0 Nop14-like family Osw5 PF17062.5 CCD26478.1 - 4.7e-32 109.9 11.6 6.2e-32 109.5 11.6 1.2 1 0 0 1 1 1 1 Outer spore wall 5 H_PPase PF03030.16 CCD26478.1 - 0.088 11.4 0.1 0.1 11.2 0.1 1.0 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DsbG_N PF18257.1 CCD26478.1 - 0.24 11.5 2.6 0.27 11.4 1.2 1.7 2 0 0 2 2 2 0 Disulfide isomerase DsbG N-terminal DUF2070 PF09843.9 CCD26478.1 - 1.7 6.9 5.2 2.1 6.6 5.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ribophorin_II PF05817.14 CCD26479.1 - 3.9e-14 52.2 2.7 5.2e-14 51.7 2.7 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Peptidase_S24 PF00717.23 CCD26480.1 - 6.5e-08 32.4 0.1 1.4e-07 31.4 0.0 1.6 1 1 1 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 CCD26480.1 - 0.0078 16.0 0.0 0.11 12.3 0.0 2.3 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 ADH_zinc_N_2 PF13602.6 CCD26481.1 - 7e-12 46.5 0.0 1.2e-11 45.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CCD26481.1 - 4.2e-07 30.0 0.0 8.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LDcluster4 PF18306.1 CCD26481.1 - 0.045 13.3 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 SLOG cluster4 family ADH_N PF08240.12 CCD26481.1 - 0.052 13.4 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CCD26482.1 - 7e-14 53.0 0.0 1.2e-13 52.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CCD26482.1 - 1e-08 35.2 0.0 2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 CCD26482.1 - 0.03 14.8 0.0 0.094 13.2 0.0 1.8 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 CCD26483.1 - 3.6e-13 50.7 0.0 6.6e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CCD26483.1 - 2e-08 34.3 0.0 2.3e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Nup35_RRM PF05172.13 CCD26484.1 - 1.2e-35 121.4 0.2 5.1e-35 119.5 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CCD26484.1 - 0.0033 17.4 0.0 0.012 15.5 0.0 2.0 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RVP_2 PF08284.11 CCD26485.1 - 0.025 14.4 0.1 0.15 11.8 0.1 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease PNK3P PF08645.11 CCD26486.1 - 9.3e-43 145.7 0.4 1.2e-42 145.3 0.4 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase EDS1_EP PF18117.1 CCD26487.1 - 0.12 12.8 0.4 0.37 11.3 0.4 1.9 1 1 0 1 1 1 0 Enhanced disease susceptibility 1 protein EP domain Ribosomal_S8 PF00410.19 CCD26488.1 - 1.4e-14 54.1 0.0 8.8e-14 51.6 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 ATG16 PF08614.11 CCD26489.1 - 5.2e-11 43.1 18.6 1.5e-10 41.7 16.6 2.0 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 CCD26489.1 - 0.002 18.7 5.4 0.002 18.7 5.4 2.2 1 1 1 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Fez1 PF06818.15 CCD26489.1 - 0.0029 18.1 8.5 0.0032 18.0 8.5 1.2 1 0 0 1 1 1 1 Fez1 GAS PF13851.6 CCD26489.1 - 0.021 14.2 18.5 0.032 13.6 16.1 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 CCD26489.1 - 0.063 13.5 11.2 0.047 13.9 9.2 1.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 CCD26489.1 - 0.099 12.7 16.5 0.032 14.2 6.5 2.7 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding OmpH PF03938.14 CCD26489.1 - 0.18 12.1 8.2 0.26 11.6 7.5 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 CCD26489.1 - 0.3 11.6 13.8 0.49 10.9 13.8 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region zf-CRD PF17979.1 CCD26489.1 - 0.34 11.0 4.8 1.1 9.4 4.8 1.8 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Atg14 PF10186.9 CCD26489.1 - 0.71 8.9 8.0 0.89 8.6 8.0 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LMBR1 PF04791.16 CCD26489.1 - 0.89 8.4 5.1 0.92 8.3 5.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Hemagglutinin PF00509.18 CCD26489.1 - 1.4 7.3 8.4 1.5 7.2 8.4 1.0 1 0 0 1 1 1 0 Haemagglutinin DUF641 PF04859.12 CCD26489.1 - 2.4 8.5 10.4 10 6.5 9.8 2.1 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) ABC_tran_CTD PF16326.5 CCD26489.1 - 3 8.2 8.6 2.4 8.5 5.5 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain SlyX PF04102.12 CCD26489.1 - 3.9 8.2 8.7 1.1 9.9 3.4 2.6 1 1 2 3 3 3 0 SlyX Ly49 PF08391.10 CCD26489.1 - 4.5 7.7 9.6 3.2 8.1 7.6 1.8 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region FAM76 PF16046.5 CCD26489.1 - 4.7 6.5 8.9 5.4 6.3 8.9 1.1 1 0 0 1 1 1 0 FAM76 protein Cep57_CLD_2 PF14197.6 CCD26489.1 - 6.1 7.0 14.3 2.4 8.3 1.8 3.9 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 KMP11 PF03037.16 CCD26490.1 - 0.21 12.4 0.2 0.21 12.4 0.2 2.4 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 DnaJ PF00226.31 CCD26491.1 - 9.3e-25 86.5 0.7 9.3e-25 86.5 0.7 1.7 2 0 0 2 2 2 1 DnaJ domain PhoLip_ATPase_C PF16212.5 CCD26492.1 - 2e-70 237.4 19.6 2e-70 237.4 19.6 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCD26492.1 - 9.7e-23 79.6 1.6 9.7e-23 79.6 1.6 2.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CCD26492.1 - 2.3e-14 53.3 0.0 8.1e-14 51.5 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 CCD26492.1 - 6.8e-12 45.3 0.0 1.1e-10 41.5 0.0 2.9 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CCD26492.1 - 1.9e-11 44.6 0.3 5.4e-05 23.6 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CCD26492.1 - 0.0063 16.3 0.2 0.0063 16.3 0.2 3.5 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase Vezatin PF12632.7 CCD26493.1 - 6e-06 25.8 18.3 6e-06 25.8 18.3 2.2 2 1 0 2 2 2 1 Mysoin-binding motif of peroxisomes Alpha-amylase PF00128.24 CCD26493.1 - 0.0015 18.2 0.7 0.0028 17.3 0.7 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain LNS2 PF08235.13 CCD26494.1 - 8.7e-92 306.7 0.0 1.7e-91 305.7 0.0 1.5 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CCD26494.1 - 3.6e-42 142.5 0.0 8.1e-42 141.3 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Mito_carr PF00153.27 CCD26495.1 - 9e-55 182.6 4.5 1.7e-25 88.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CCD26495.1 - 1.2e-07 31.1 0.1 0.0035 16.6 0.0 2.4 2 0 0 2 2 2 2 Gammaproteobacterial serine protease Mlh1_C PF16413.5 CCD26496.1 - 7.1e-84 281.4 0.1 2.3e-83 279.7 0.1 1.9 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CCD26496.1 - 9.3e-30 102.8 0.3 2e-29 101.7 0.3 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CCD26496.1 - 2.9e-13 49.8 0.1 7.5e-13 48.5 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CCD26496.1 - 6.8e-07 29.8 0.0 2.1e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cep3 PF16846.5 CCD26497.1 - 3.5e-219 728.5 24.7 4.1e-219 728.3 24.7 1.0 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B Zn_clus PF00172.18 CCD26497.1 - 8.6e-07 29.0 7.7 1.5e-06 28.2 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 CCD26498.1 - 2.8e-159 530.6 0.0 3.2e-159 530.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SPRY PF00622.28 CCD26500.1 - 6e-10 39.3 0.0 1.4e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 SPRY domain Pur_ac_phosph_N PF16656.5 CCD26500.1 - 0.042 14.4 0.1 0.2 12.2 0.1 2.2 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain DUF3824 PF12868.7 CCD26500.1 - 1.9 9.2 6.6 1 10.0 3.3 2.3 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) HECT PF00632.25 CCD26501.1 - 9.5e-87 291.3 0.3 1.6e-86 290.6 0.3 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Glyco_transf_22 PF03901.17 CCD26502.1 - 3.7e-99 332.8 42.3 4.4e-99 332.5 42.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family AbiH PF14253.6 CCD26502.1 - 0.007 16.3 0.8 0.012 15.5 0.8 1.4 1 0 0 1 1 1 1 Bacteriophage abortive infection AbiH PCRF PF03462.18 CCD26503.1 - 3.7e-55 186.8 1.0 1.1e-54 185.2 0.0 2.0 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 CCD26503.1 - 2e-37 127.6 3.5 2e-37 127.6 3.5 1.7 2 0 0 2 2 2 1 RF-1 domain MIR PF02815.19 CCD26503.1 - 0.0037 17.1 1.6 0.23 11.3 0.2 2.4 2 0 0 2 2 2 2 MIR domain Turandot PF07240.11 CCD26503.1 - 0.13 12.2 0.2 0.75 9.8 0.1 2.4 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot PEX11 PF05648.14 CCD26503.1 - 0.71 9.3 3.6 0.26 10.7 0.2 1.8 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) PP2C PF00481.21 CCD26504.1 - 4.3e-48 164.2 0.0 7.7e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 CCD26504.1 - 1.1e-40 137.2 81.0 1.2e-10 41.0 5.1 9.6 6 3 2 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 CCD26504.1 - 9.8e-31 105.3 88.5 3.3e-05 24.1 0.7 12.2 10 2 2 12 12 12 9 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 CCD26504.1 - 3.9e-22 78.7 0.0 7.7e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 CCD26504.1 - 0.00083 18.9 5.3 0.00083 18.9 5.3 5.5 2 2 4 6 6 6 4 Leucine-rich repeat Ad_cyc_g-alpha PF08509.11 CCD26504.1 - 0.00086 19.0 0.1 0.0029 17.3 0.1 1.8 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_5 PF13306.6 CCD26504.1 - 0.3 11.1 23.3 0.75 9.8 1.0 4.5 2 1 1 4 4 4 0 BspA type Leucine rich repeat region (6 copies) DUF676 PF05057.14 CCD26505.1 - 3.6e-59 199.9 0.0 6e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 CCD26505.1 - 0.00075 19.4 0.0 0.0019 18.1 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) LCAT PF02450.15 CCD26505.1 - 0.035 13.3 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 CCD26505.1 - 0.1 12.3 0.0 0.36 10.5 0.0 1.9 1 0 0 1 1 1 0 PGAP1-like protein Phage_Gp23 PF10669.9 CCD26505.1 - 2 8.8 6.0 5.1 7.5 6.0 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) RINT1_TIP1 PF04437.13 CCD26506.1 - 3.6e-89 300.0 32.4 3.6e-89 300.0 32.4 1.7 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Suppressor_APC PF11414.8 CCD26506.1 - 0.52 10.4 4.2 0.43 10.7 0.4 2.6 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Polyoma_coat2 PF00761.20 CCD26506.1 - 1.9 8.1 4.2 16 5.1 0.3 2.6 2 1 1 3 3 3 0 Polyomavirus coat protein Osmo_CC PF08946.10 CCD26506.1 - 2.9 8.2 9.0 1.8 8.9 0.4 3.7 3 0 0 3 3 3 0 Osmosensory transporter coiled coil EMP24_GP25L PF01105.24 CCD26507.1 - 4.9e-12 46.1 0.1 6.7e-12 45.7 0.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RNase_PH PF01138.21 CCD26508.1 - 7.3e-08 33.0 0.1 1.2e-07 32.3 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CCD26508.1 - 0.0024 17.9 0.0 0.0053 16.8 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MAP PF03642.13 CCD26508.1 - 0.042 14.2 0.4 0.13 12.6 0.3 1.9 1 1 1 2 2 2 0 MAP domain Ribosomal_L6 PF00347.23 CCD26509.1 - 1.5e-29 102.5 13.1 2.5e-15 56.9 5.7 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 CPT_N PF16484.5 CCD26509.1 - 0.13 12.2 0.1 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Carnitine O-palmitoyltransferase N-terminus Chorismate_synt PF01264.21 CCD26510.1 - 2.3e-140 467.0 0.1 2.6e-140 466.8 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase Flavodoxin_2 PF02525.17 CCD26511.1 - 1.1e-54 185.2 0.0 1.4e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CCD26511.1 - 6.1e-14 52.0 0.0 1.6e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 NADPH-dependent FMN reductase SNF2_N PF00176.23 CCD26512.1 - 1.8e-65 221.0 1.2 1.8e-65 221.0 1.2 2.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 CCD26512.1 - 3.6e-44 150.4 21.0 3.6e-44 150.4 21.0 5.1 4 1 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 CCD26512.1 - 4e-17 62.6 5.6 4.9e-17 62.3 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Fe_hyd_lg_C PF02906.14 CCD26512.1 - 1.6 8.3 11.4 0.34 10.5 4.8 2.6 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain Med5 PF08689.10 CCD26513.1 - 0 1502.8 61.5 0 1502.6 61.5 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 Pex14_N PF04695.13 CCD26514.1 - 3.3e-28 99.3 2.0 3.3e-28 99.3 2.0 3.3 3 2 0 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF892 PF05974.12 CCD26514.1 - 0.01 15.8 1.4 0.02 14.9 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF892) DUF1043 PF06295.12 CCD26514.1 - 0.062 13.3 9.2 1.3 9.0 9.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) SHE3 PF17078.5 CCD26514.1 - 0.066 12.9 12.3 0.13 11.9 12.3 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 LURAP PF14854.6 CCD26514.1 - 0.088 12.8 0.8 0.27 11.2 0.5 2.0 1 1 1 2 2 2 0 Leucine rich adaptor protein Baculo_PEP_C PF04513.12 CCD26514.1 - 0.11 12.6 7.2 0.3 11.1 7.0 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 CCD26514.1 - 0.15 11.4 3.7 0.24 10.7 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 CCD26514.1 - 0.16 11.4 12.4 0.27 10.7 12.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.11 CCD26514.1 - 0.18 10.7 11.1 0.29 10.0 11.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CCDC-167 PF15188.6 CCD26514.1 - 0.18 12.2 9.2 1.9 8.9 0.7 2.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 LMBR1 PF04791.16 CCD26514.1 - 0.18 10.7 0.8 0.22 10.4 0.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Prefoldin_2 PF01920.20 CCD26514.1 - 0.23 11.4 17.8 0.14 12.1 5.9 3.5 2 1 2 4 4 3 0 Prefoldin subunit GTP-bdg_M PF16360.5 CCD26514.1 - 0.24 12.0 2.6 1.1 9.9 0.3 2.6 2 1 0 2 2 2 0 GTP-binding GTPase Middle Region V_ATPase_I PF01496.19 CCD26514.1 - 0.27 9.1 4.9 0.35 8.7 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 CCD26514.1 - 0.39 10.8 7.2 2.8 8.0 7.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 CCD26514.1 - 0.41 11.1 16.7 0.71 10.3 13.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Nsp1_C PF05064.13 CCD26514.1 - 0.48 10.2 8.3 1.5 8.7 2.6 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region Nup88 PF10168.9 CCD26514.1 - 0.69 7.6 9.9 0.94 7.2 9.9 1.1 1 0 0 1 1 1 0 Nuclear pore component zf-C4H2 PF10146.9 CCD26514.1 - 0.73 10.1 15.2 1.3 9.3 15.2 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein DUF5082 PF16888.5 CCD26514.1 - 0.95 9.7 12.1 1.4 9.2 5.1 3.0 3 0 0 3 3 2 0 Domain of unknown function (DUF5082) CdvA PF18822.1 CCD26514.1 - 1.3 8.9 13.7 0.83 9.5 3.5 3.1 1 1 2 3 3 3 0 CdvA-like coiled-coil domain SlyX PF04102.12 CCD26514.1 - 1.4 9.6 6.7 0.48 11.1 1.3 2.8 2 1 1 3 3 3 0 SlyX ALMT PF11744.8 CCD26514.1 - 1.9 7.3 6.3 5.4 5.7 6.3 1.8 1 1 0 1 1 1 0 Aluminium activated malate transporter Rx_N PF18052.1 CCD26514.1 - 2.4 8.5 9.3 1.1e+02 3.2 9.4 2.5 1 1 0 1 1 1 0 Rx N-terminal domain Tup_N PF08581.10 CCD26514.1 - 3 8.2 13.4 3.1 8.2 11.2 2.1 2 0 0 2 2 2 0 Tup N-terminal HIP1_clath_bdg PF16515.5 CCD26514.1 - 3.1 8.5 10.9 1.3 9.7 7.1 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5339 PF17274.2 CCD26514.1 - 3.8 8.4 6.5 14 6.6 0.0 2.7 1 1 0 2 2 2 0 Family of unknown function (DUF5339) DUF948 PF06103.11 CCD26514.1 - 4 7.8 6.9 1.9 8.8 2.0 2.2 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Ax_dynein_light PF10211.9 CCD26514.1 - 4.2 7.3 15.5 3.9 7.4 6.4 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain TMPIT PF07851.13 CCD26514.1 - 5.1 6.3 9.7 2.8 7.1 5.6 1.9 1 1 1 2 2 2 0 TMPIT-like protein ACPS PF01648.20 CCD26515.1 - 1.3e-10 41.4 0.0 2.7e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Prenyltrans PF00432.21 CCD26516.1 - 1.2e-31 108.1 7.0 8.9e-08 31.8 0.1 6.2 6 1 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 CCD26516.1 - 0.017 14.3 0.0 0.041 13.0 0.0 1.7 2 1 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain NAD_binding_6 PF08030.12 CCD26517.1 - 1.4e-16 61.0 0.2 2.2e-16 60.4 0.2 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 CCD26517.1 - 1e-15 58.0 11.8 1e-15 58.0 11.8 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CCD26517.1 - 5.1e-05 23.3 0.2 0.00014 21.9 0.2 1.7 1 0 0 1 1 1 1 FAD-binding domain GCIP PF13324.6 CCD26517.1 - 0.93 9.0 4.8 1.5 8.4 4.8 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Glyco_hydro_38N PF01074.22 CCD26518.1 - 1.7e-81 273.7 0.4 2.7e-81 273.1 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CCD26518.1 - 7.4e-52 176.5 0.1 1.7e-51 175.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CCD26518.1 - 7e-27 93.4 0.0 2e-26 92.0 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 CCD26518.1 - 6.3e-10 39.0 0.9 4.9e-09 36.2 0.9 2.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Pkinase PF00069.25 CCD26519.1 - 2.9e-61 207.2 0.0 6.5e-61 206.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26519.1 - 4.5e-27 95.0 0.0 1e-26 93.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD26519.1 - 2.9e-05 23.6 0.1 0.25 10.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CCD26519.1 - 0.00046 19.6 0.0 0.00086 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CCD26519.1 - 0.0025 17.5 0.2 0.019 14.6 0.1 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CCD26519.1 - 0.027 14.4 0.1 0.21 11.5 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family UPF0029 PF01205.19 CCD26520.1 - 1.2e-31 109.2 0.1 1.9e-31 108.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 TraH_2 PF06871.11 CCD26520.1 - 0.063 12.9 0.1 2 8.0 0.0 2.1 1 1 1 2 2 2 0 TraH_2 IgGFc_binding PF17517.2 CCD26521.1 - 0.16 11.2 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 IgGFc binding protein OCD_Mu_crystall PF02423.15 CCD26522.1 - 5.3e-09 35.5 0.2 2.8e-05 23.2 0.0 2.5 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Nsp3_PL2pro PF12124.8 CCD26522.1 - 0.13 12.1 0.0 0.69 9.7 0.0 2.0 2 0 0 2 2 2 0 Coronavirus polyprotein cleavage domain SH3BGR PF04908.15 CCD26523.1 - 0.023 14.8 0.0 0.023 14.8 0.0 3.8 4 0 0 4 4 4 0 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 CCD26523.1 - 0.12 12.6 0.0 0.79 10.0 0.0 2.5 2 0 0 2 2 2 0 Glutaredoxin Arf PF00025.21 CCD26523.1 - 0.26 10.7 0.0 0.26 10.7 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family Glycogen_syn PF05693.13 CCD26524.1 - 0 1140.4 0.0 0 1140.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 CCD26524.1 - 4.6e-08 32.8 0.0 5.3e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCD26524.1 - 2.8e-07 31.1 0.0 0.0016 18.9 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCD26524.1 - 5.4e-05 23.3 0.4 0.00015 21.8 0.4 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CCD26524.1 - 0.00025 21.5 0.1 0.00061 20.3 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 CCD26524.1 - 0.00043 20.1 0.2 0.0011 18.7 0.2 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Pkinase PF00069.25 CCD26525.1 - 5.1e-72 242.4 0.0 7.9e-72 241.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26525.1 - 3.8e-41 141.1 0.0 5.8e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCD26525.1 - 0.00077 18.3 0.5 0.0022 16.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CCD26525.1 - 0.0069 15.7 0.9 0.017 14.5 0.0 2.1 2 1 1 3 3 3 1 Kinase-like ABC1 PF03109.16 CCD26525.1 - 0.014 15.6 0.0 0.048 13.8 0.0 1.9 2 0 0 2 2 2 0 ABC1 family Kdo PF06293.14 CCD26525.1 - 0.053 12.9 0.2 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family WHIM1 PF15612.6 CCD26526.1 - 0.00063 19.2 0.1 0.002 17.6 0.1 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WYL_3 PF18488.1 CCD26526.1 - 0.041 14.2 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 WYL domain Ins_allergen_rp PF06757.13 CCD26526.1 - 0.045 13.7 3.2 1 9.3 0.9 3.3 3 0 0 3 3 3 0 Insect allergen related repeat, nitrile-specifier detoxification DUF4606 PF15379.6 CCD26526.1 - 4.5 7.6 8.8 0.27 11.5 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) DUF1690 PF07956.11 CCD26527.1 - 2.8e-35 121.8 18.2 5.6e-35 120.8 18.2 1.5 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF445 PF04286.12 CCD26527.1 - 0.46 10.2 12.4 0.58 9.9 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) UCH PF00443.29 CCD26528.1 - 5.4e-50 170.3 5.5 6.9e-50 169.9 5.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCD26528.1 - 6.5e-10 39.1 12.5 1.4e-08 34.7 12.5 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CCD26528.1 - 0.00013 21.7 0.0 0.00035 20.3 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Uteroglobin PF01099.17 CCD26528.1 - 0.08 13.3 0.1 0.25 11.7 0.1 1.9 1 0 0 1 1 1 0 Uteroglobin family RNB PF00773.19 CCD26529.1 - 2.1e-98 329.6 0.7 3.9e-97 325.5 0.0 2.1 2 0 0 2 2 2 1 RNB domain Rrp44_CSD1 PF17216.3 CCD26529.1 - 2.6e-75 251.1 0.2 1.4e-74 248.8 0.1 2.2 2 0 0 2 2 2 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 CCD26529.1 - 5.7e-30 103.1 3.3 1.5e-29 101.7 3.3 1.8 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 CCD26529.1 - 4.1e-17 62.0 0.0 1.1e-16 60.6 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 CCD26529.1 - 6.9e-16 58.7 1.2 1.7e-15 57.5 1.2 1.6 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 CCD26529.1 - 8.9e-05 22.6 0.0 0.028 14.6 0.0 3.2 3 0 0 3 3 3 1 Cold shock domain PIN_12 PF16289.5 CCD26529.1 - 0.0071 16.9 2.1 0.026 15.0 2.1 2.1 1 1 0 1 1 1 1 PIN domain OB_RNB PF08206.11 CCD26529.1 - 0.038 13.7 0.0 0.15 11.7 0.0 2.0 1 0 0 1 1 1 0 Ribonuclease B OB domain Dis3l2_C_term PF17877.1 CCD26529.1 - 0.095 13.0 0.3 0.095 13.0 0.3 2.0 2 0 0 2 2 2 0 DIS3-like exonuclease 2 C terminal Lipase_GDSL_3 PF14606.6 CCD26529.1 - 0.29 11.2 1.5 17 5.5 0.0 2.5 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family ABC_tran PF00005.27 CCD26530.1 - 5.9e-47 159.6 0.2 1.9e-22 80.2 0.0 3.0 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CCD26530.1 - 2e-19 69.4 10.5 2e-19 69.4 10.5 2.8 4 0 0 4 4 1 1 ABC transporter AAA_21 PF13304.6 CCD26530.1 - 5.3e-15 56.0 10.4 0.0012 18.7 0.0 5.2 3 2 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCD26530.1 - 4.8e-11 42.5 0.0 0.00018 21.0 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CCD26530.1 - 5.2e-07 30.2 0.1 0.036 14.5 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 CCD26530.1 - 5.6e-07 30.2 0.5 0.073 13.6 0.1 3.9 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 CCD26530.1 - 7.8e-07 29.5 1.1 0.045 14.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 CCD26530.1 - 3e-06 26.9 0.6 0.13 12.1 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCD26530.1 - 3.7e-06 27.0 0.1 0.076 12.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 CCD26530.1 - 3.9e-06 26.9 0.0 0.025 14.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 CCD26530.1 - 8.4e-06 26.1 0.5 0.31 11.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 CCD26530.1 - 1.7e-05 25.2 0.1 0.092 13.2 0.0 3.7 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 CCD26530.1 - 6.3e-05 23.0 1.5 0.11 12.6 0.3 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_14 PF13173.6 CCD26530.1 - 0.00014 21.9 2.8 0.37 10.8 0.0 3.6 4 0 0 4 4 2 2 AAA domain AAA_33 PF13671.6 CCD26530.1 - 0.00016 21.8 0.3 0.31 11.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 CCD26530.1 - 0.00021 21.0 0.0 0.035 13.8 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 CCD26530.1 - 0.00026 20.8 25.6 0.028 14.2 0.0 4.6 3 1 1 4 4 3 2 AAA ATPase domain AAA_23 PF13476.6 CCD26530.1 - 0.00027 21.5 28.3 0.14 12.7 0.0 5.2 5 0 0 5 5 5 2 AAA domain AAA_24 PF13479.6 CCD26530.1 - 0.00027 20.7 0.0 0.77 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CCD26530.1 - 0.00029 20.6 0.0 2.1 8.0 0.0 3.8 4 0 0 4 4 4 1 AAA domain PduV-EutP PF10662.9 CCD26530.1 - 0.00034 20.4 0.1 0.31 10.8 0.0 2.8 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 CCD26530.1 - 0.00052 20.4 0.6 0.63 10.5 0.0 3.2 3 0 0 3 3 2 1 RNA helicase NB-ARC PF00931.22 CCD26530.1 - 0.0009 18.5 0.2 0.55 9.4 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain Zeta_toxin PF06414.12 CCD26530.1 - 0.0011 18.3 0.7 0.28 10.5 0.0 2.9 3 0 0 3 3 2 1 Zeta toxin NTPase_1 PF03266.15 CCD26530.1 - 0.0011 18.9 0.0 0.34 10.8 0.0 2.6 2 0 0 2 2 2 1 NTPase Roc PF08477.13 CCD26530.1 - 0.0011 19.1 0.1 1.7 8.9 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 CCD26530.1 - 0.0012 18.4 0.0 0.42 10.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region MeaB PF03308.16 CCD26530.1 - 0.0019 17.3 0.0 0.33 9.9 0.0 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 CCD26530.1 - 0.0025 17.8 0.0 0.59 10.1 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Blo-t-5 PF11642.8 CCD26530.1 - 0.0026 17.7 0.8 0.0026 17.7 0.8 2.4 2 0 0 2 2 1 1 Mite allergen Blo t 5 AAA_5 PF07728.14 CCD26530.1 - 0.0034 17.4 1.2 4.2 7.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 CCD26530.1 - 0.0039 17.3 3.0 0.25 11.4 0.0 3.6 4 0 0 4 4 3 1 Dynamin family DUF815 PF05673.13 CCD26530.1 - 0.0054 15.9 0.1 3.2 6.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) G-alpha PF00503.20 CCD26530.1 - 0.0058 15.8 3.9 0.58 9.2 0.0 3.1 3 0 0 3 3 3 1 G-protein alpha subunit MobB PF03205.14 CCD26530.1 - 0.01 15.7 0.0 0.22 11.4 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 CCD26530.1 - 0.012 15.1 0.0 1.2 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 CCD26530.1 - 0.015 14.6 0.4 4.5 6.5 0.0 2.7 2 1 0 2 2 2 0 Septin FeoB_N PF02421.18 CCD26530.1 - 0.019 14.5 0.0 7.7 6.0 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B SRP54 PF00448.22 CCD26530.1 - 0.025 14.2 0.1 2.4 7.7 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 CCD26530.1 - 0.045 13.7 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain Pox_A32 PF04665.12 CCD26530.1 - 0.045 13.2 0.5 0.76 9.2 0.0 2.7 3 0 0 3 3 3 0 Poxvirus A32 protein cobW PF02492.19 CCD26530.1 - 0.054 13.1 0.1 5.7 6.5 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 CCD26530.1 - 0.062 12.7 0.1 0.7 9.3 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF2813 PF11398.8 CCD26530.1 - 0.072 12.3 7.6 0.27 10.5 0.0 4.0 3 1 0 4 4 4 0 Protein of unknown function (DUF2813) Viral_helicase1 PF01443.18 CCD26530.1 - 0.11 12.2 0.0 3.5 7.3 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.18 CCD26530.1 - 0.15 11.4 0.5 2.2 7.6 0.0 2.5 3 0 0 3 3 2 0 FtsK/SpoIIIE family Ras PF00071.22 CCD26530.1 - 0.15 11.6 2.2 8.4 6.0 0.0 3.1 3 0 0 3 3 3 0 Ras family AAA_17 PF13207.6 CCD26530.1 - 0.15 12.5 5.4 12 6.4 0.0 3.9 3 1 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 CCD26530.1 - 0.3 11.0 9.3 0.52 10.2 0.0 3.1 4 0 0 4 4 2 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 CCD26530.1 - 0.75 9.8 0.0 0.75 9.8 0.0 5.1 4 1 1 5 5 5 0 Helicase HerA, central domain RCSD PF05177.12 CCD26531.1 - 0.027 15.4 3.9 0.076 13.9 3.9 1.8 1 0 0 1 1 1 0 RCSD region Rep_Org_C PF06926.11 CCD26531.1 - 0.1 13.0 0.2 0.1 13.0 0.2 2.5 3 0 0 3 3 3 0 Putative replisome organiser protein C-terminus Peptidase_M28 PF04389.17 CCD26532.1 - 4.5e-33 114.6 0.0 1.4e-32 113.0 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M28 PIP5K PF01504.18 CCD26533.1 - 4.8e-42 144.1 0.2 2.9e-36 125.1 0.5 5.2 4 1 1 5 5 5 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 CCD26533.1 - 2.7e-27 95.6 0.0 5.1e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 CCD26533.1 - 2.4e-17 62.8 7.9 2.4e-17 62.8 7.9 1.8 2 0 0 2 2 2 1 FYVE zinc finger OrfB_IS605 PF01385.19 CCD26533.1 - 1.5 9.1 8.0 0.4 10.9 2.8 2.8 3 0 0 3 3 3 0 Probable transposase IBR PF01485.21 CCD26533.1 - 7.6 6.8 9.3 2.6 8.3 5.4 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain WD40 PF00400.32 CCD26534.1 - 7.8e-08 32.9 0.0 0.017 16.0 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD26534.1 - 8e-08 32.5 0.0 0.047 14.0 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCD26534.1 - 0.013 14.5 0.9 3.8 6.4 0.1 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Arrestin_C PF02752.22 CCD26535.1 - 1.4e-23 83.9 1.2 4e-22 79.1 0.7 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCD26535.1 - 7.5e-06 26.1 0.0 0.00014 21.9 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CCD26535.1 - 0.0037 17.0 0.0 0.013 15.2 0.0 1.9 2 0 0 2 2 2 1 Arrestin_N terminal like Asparaginase_C PF17763.1 CCD26536.1 - 0.0016 18.6 0.1 0.0062 16.7 0.1 1.9 1 1 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Far-17a_AIG1 PF04750.14 CCD26537.1 - 3.7e-13 49.3 6.2 4.8e-13 48.9 6.2 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Ribosomal_L44 PF00935.19 CCD26538.1 - 3.1e-36 123.7 11.4 4.7e-36 123.1 11.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Chs7 PF12271.8 CCD26539.1 - 9.1e-115 382.9 20.0 1e-114 382.8 20.0 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone CytochromB561_N PF09786.9 CCD26540.1 - 1.2 8.1 28.8 1.4 7.8 28.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DNA_RNApol_7kD PF03604.13 CCD26541.1 - 1.1e-16 60.2 1.7 1.4e-16 59.9 1.7 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf_UBZ PF18439.1 CCD26541.1 - 0.004 16.7 0.8 1.5 8.5 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DZR PF12773.7 CCD26541.1 - 0.0067 16.4 0.4 0.0095 15.9 0.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon TFIIS_C PF01096.18 CCD26541.1 - 0.011 15.6 0.9 3.9 7.4 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) HypA PF01155.19 CCD26541.1 - 0.012 15.6 0.2 0.012 15.6 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MCM_OB PF17207.3 CCD26541.1 - 0.019 14.8 0.2 0.021 14.7 0.2 1.1 1 0 0 1 1 1 0 MCM OB domain zinc-ribbons_6 PF07191.12 CCD26541.1 - 0.019 14.9 0.4 0.025 14.6 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbons IrmA PF18673.1 CCD26541.1 - 0.073 13.2 0.0 0.081 13.1 0.0 1.1 1 0 0 1 1 1 0 interleukin receptor mimic protein A Ribosomal_L40e PF01020.17 CCD26541.1 - 0.08 12.8 2.4 0.11 12.4 2.4 1.3 1 0 0 1 1 1 0 Ribosomal L40e family DUF4428 PF14471.6 CCD26541.1 - 0.085 12.8 1.4 1.5 8.8 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) Zn_ribbon_SprT PF17283.2 CCD26541.1 - 0.098 12.6 2.5 0.17 11.8 1.9 1.7 1 1 2 3 3 3 0 SprT-like zinc ribbon domain DUF2197 PF09963.9 CCD26541.1 - 0.12 12.6 2.5 8.4 6.7 0.2 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) FYDLN_acid PF09538.10 CCD26541.1 - 0.16 12.7 0.5 0.18 12.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zn-ribbon_8 PF09723.10 CCD26541.1 - 0.23 11.6 3.2 0.81 9.9 3.1 1.9 1 1 2 3 3 3 0 Zinc ribbon domain zinc_ribbon_10 PF10058.9 CCD26541.1 - 0.25 11.1 2.1 0.72 9.6 0.1 2.0 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_ribbon_recom PF13408.6 CCD26541.1 - 0.26 11.9 2.9 3.7 8.1 0.6 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Rubredoxin_2 PF18073.1 CCD26541.1 - 0.53 10.1 2.7 9.7 6.0 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Ribosomal_L44 PF00935.19 CCD26541.1 - 1.6 9.3 5.1 13 6.3 0.7 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 AMPK1_CBM PF16561.5 CCD26542.1 - 1.3e-13 50.9 0.2 3.2e-13 49.7 0.2 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Rick_17kDa_Anti PF05433.15 CCD26543.1 - 0.24 11.3 1.6 0.44 10.4 1.6 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain SHR3_chaperone PF08229.11 CCD26544.1 - 1e-71 239.8 2.6 1.5e-71 239.3 2.6 1.3 1 1 0 1 1 1 1 ER membrane protein SH3 Phage_HK97_TLTM PF06120.11 CCD26544.1 - 0.022 14.0 0.2 0.029 13.6 0.2 1.1 1 0 0 1 1 1 0 Tail length tape measure protein DUF202 PF02656.15 CCD26544.1 - 0.071 13.6 3.9 0.67 10.4 0.1 2.6 2 1 1 3 3 2 0 Domain of unknown function (DUF202) Ras PF00071.22 CCD26545.1 - 4.4e-43 146.7 0.1 6.5e-43 146.1 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD26545.1 - 5e-18 65.5 0.0 2.3e-17 63.3 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD26545.1 - 8.7e-05 22.0 0.5 0.00023 20.6 0.5 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CCD26545.1 - 0.00013 21.5 0.1 0.00048 19.7 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RRM_1 PF00076.22 CCD26546.1 - 3.4e-06 26.8 0.0 7.5e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCD26546.1 - 0.0018 18.3 0.0 0.0068 16.5 0.0 1.9 1 1 1 2 2 2 1 RNA recognition motif DUF410 PF04190.13 CCD26546.1 - 0.074 12.8 0.4 0.1 12.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF410) LMBR1 PF04791.16 CCD26546.1 - 1.6 7.6 4.5 1.9 7.3 4.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pkinase PF00069.25 CCD26547.1 - 8.1e-46 156.5 0.1 1.7e-45 155.4 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26547.1 - 8e-18 64.7 0.0 1.7e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCD26547.1 - 0.14 12.1 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ELFV_dehydrog PF00208.21 CCD26548.1 - 3.6e-61 207.0 0.1 2.2e-59 201.1 0.1 2.4 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CCD26548.1 - 1.5e-18 65.9 0.2 4.1e-12 44.5 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 CCD26548.1 - 0.0013 18.6 0.0 0.0093 15.8 0.0 2.2 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Cadherin_2 PF08266.12 CCD26548.1 - 0.034 14.0 0.0 0.28 11.1 0.0 2.5 2 0 0 2 2 2 0 Cadherin-like JAB PF01398.21 CCD26549.1 - 2e-29 102.0 0.2 5.4e-29 100.6 0.2 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CCD26549.1 - 0.00041 20.1 0.0 0.00089 19.0 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CCD26549.1 - 0.018 15.1 0.5 0.33 11.0 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0172) S_100 PF01023.19 CCD26549.1 - 0.085 12.6 0.1 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Tim17 PF02466.19 CCD26550.1 - 9.2e-37 125.8 4.5 1.2e-36 125.5 4.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Serine_protease PF18405.1 CCD26550.1 - 0.11 11.7 0.5 0.25 10.4 0.0 1.7 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Arm PF00514.23 CCD26551.1 - 3.2e-22 77.8 10.4 1.4e-05 25.0 0.2 7.4 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat IBB PF01749.20 CCD26551.1 - 7.9e-16 58.3 3.6 9.6e-16 58.0 2.0 2.1 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 CCD26551.1 - 2.8e-06 26.8 0.7 3.9e-05 23.1 0.1 2.6 2 0 0 2 2 2 1 Atypical Arm repeat MARVEL PF01284.23 CCD26553.1 - 1.2e-26 93.5 11.6 1.8e-26 92.9 11.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF4834 PF16118.5 CCD26553.1 - 0.0089 17.0 7.5 0.11 13.5 1.4 3.9 3 1 0 3 3 3 1 Domain of unknown function (DUF4834) HXXEE PF13787.6 CCD26553.1 - 0.071 13.9 6.7 0.046 14.5 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif DUF1761 PF08570.10 CCD26553.1 - 0.59 10.4 6.9 0.55 10.5 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) LptF_LptG PF03739.14 CCD26553.1 - 1.7 7.4 6.5 0.61 8.9 0.9 2.1 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Amastin PF07344.11 CCD26553.1 - 6.7 6.5 10.9 47 3.8 10.9 2.0 1 1 0 1 1 1 0 Amastin surface glycoprotein Tyr_Deacylase PF02580.16 CCD26554.1 - 1.4e-52 178.0 0.1 1.6e-52 177.9 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase CDC13_N PF16853.5 CCD26555.1 - 1.1e-84 283.1 13.3 1.1e-84 283.1 13.3 3.1 2 0 0 2 2 2 1 Cell division control protein 13 N-terminus POT1 PF02765.17 CCD26555.1 - 1.6e-12 47.4 3.5 7.8e-12 45.2 1.0 3.3 3 0 0 3 3 3 1 Telomeric single stranded DNA binding POT1/CDC13 Cdc13_OB4_dimer PF18233.1 CCD26555.1 - 1.5e-09 38.0 0.8 5.2e-09 36.2 0.3 2.3 2 0 0 2 2 2 1 Cdc13 OB4 dimerization domain SUR7 PF06687.12 CCD26556.1 - 4.8e-43 147.3 5.9 5.9e-43 147.0 5.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2417 PF10329.9 CCD26556.1 - 0.0075 15.7 2.0 0.012 15.0 0.8 1.8 2 0 0 2 2 2 1 Region of unknown function (DUF2417) Fig1 PF12351.8 CCD26556.1 - 0.03 14.3 5.1 0.06 13.3 5.1 1.5 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 InvH PF04741.12 CCD26556.1 - 0.057 13.3 0.4 0.1 12.5 0.4 1.4 1 0 0 1 1 1 0 InvH outer membrane lipoprotein Hum_adeno_E3A PF05393.11 CCD26556.1 - 0.1 12.6 0.4 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein TatC PF00902.18 CCD26556.1 - 0.4 10.5 10.9 0.038 13.8 6.1 1.7 2 0 0 2 2 2 0 Sec-independent protein translocase protein (TatC) DUF3784 PF12650.7 CCD26556.1 - 7.2 6.9 11.1 0.11 12.7 2.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) FUSC-like PF12805.7 CCD26557.1 - 0.15 11.2 0.5 1e+02 1.9 0.0 3.8 3 1 1 4 4 4 0 FUSC-like inner membrane protein yccS RRM_1 PF00076.22 CCD26558.1 - 9.7e-15 54.2 0.0 1.6e-13 50.3 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Septin PF00735.18 CCD26559.1 - 1.6e-71 240.8 7.0 2.5e-63 214.0 3.7 2.5 2 0 0 2 2 2 2 Septin Sigma_1s PF02454.16 CCD26559.1 - 0.00089 19.2 0.0 0.0028 17.6 0.0 1.8 1 0 0 1 1 1 1 Sigma 1s protein RsgA_GTPase PF03193.16 CCD26559.1 - 0.0016 18.4 0.1 0.06 13.3 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 CCD26559.1 - 0.0018 18.4 0.0 0.0082 16.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCD26559.1 - 0.0027 18.0 0.6 0.013 15.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 CCD26559.1 - 0.0052 16.5 0.1 0.027 14.2 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CCD26559.1 - 0.008 16.7 1.1 0.029 14.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CCD26559.1 - 0.018 14.6 0.1 0.037 13.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AIG1 PF04548.16 CCD26559.1 - 0.023 14.0 1.9 0.17 11.2 0.0 2.4 2 0 0 2 2 2 0 AIG1 family LIN52 PF10044.9 CCD26559.1 - 0.024 15.4 2.7 0.041 14.6 0.3 2.8 3 0 0 3 3 2 0 Retinal tissue protein Pox_A32 PF04665.12 CCD26559.1 - 0.024 14.1 0.0 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein Roc PF08477.13 CCD26559.1 - 0.067 13.4 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 CCD26559.1 - 0.076 13.4 0.1 0.22 11.9 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CCD26559.1 - 0.085 13.3 0.0 0.26 11.7 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Dynamin_N PF00350.23 CCD26559.1 - 0.13 12.3 0.0 0.13 12.3 0.0 3.3 3 1 0 3 3 2 0 Dynamin family Mg_chelatase PF01078.21 CCD26559.1 - 0.15 11.4 0.3 0.71 9.2 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Synaptobrevin PF00957.21 CCD26559.1 - 2.7 7.8 5.8 0.47 10.3 1.0 2.3 3 0 0 3 3 2 0 Synaptobrevin ArfGap PF01412.18 CCD26561.1 - 2e-32 111.7 0.0 2e-32 111.7 0.0 2.4 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf Rhomboid_N PF12122.8 CCD26561.1 - 0.0025 17.9 1.9 0.0034 17.5 0.0 2.2 3 0 0 3 3 3 1 Cytoplasmic N-terminal domain of rhomboid serine protease Auxin_canalis PF05703.11 CCD26561.1 - 0.0056 16.6 1.2 0.011 15.7 1.2 1.4 1 0 0 1 1 1 1 Auxin canalisation Cytochrome_CBB3 PF13442.6 CCD26561.1 - 0.032 14.5 0.8 9.7 6.6 0.0 3.1 3 1 0 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III Hom_end PF05204.14 CCD26562.1 - 6.2e-41 139.0 0.0 5.9e-36 123.0 0.0 2.6 2 0 0 2 2 2 2 Homing endonuclease Hom_end_hint PF05203.16 CCD26562.1 - 2.9e-39 135.4 0.0 3.7e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Hom_end-associated Hint LAGLIDADG_3 PF14528.6 CCD26562.1 - 2.2e-08 34.3 0.0 1.7e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 LAGLIDADG-like domain DUF1794 PF08768.11 CCD26562.1 - 0.0007 19.6 0.3 0.0015 18.5 0.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1794) HSP70 PF00012.20 CCD26563.1 - 1.2e-228 760.2 7.3 1.3e-228 760.0 7.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCD26563.1 - 7.3e-16 57.9 0.5 2.5e-14 52.9 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CCD26563.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CCD26563.1 - 0.032 14.6 4.1 3 8.3 0.1 3.5 3 2 0 3 3 3 0 Cell division protein FtsA Y_phosphatase PF00102.27 CCD26564.1 - 5.2e-55 186.6 3.4 3e-54 184.1 3.4 1.9 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CCD26564.1 - 0.00044 20.1 0.1 0.0015 18.3 0.1 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CCD26564.1 - 0.0031 17.5 0.0 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CCD26564.1 - 0.019 15.1 0.1 0.062 13.4 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate ArAE_2_N PF10337.9 CCD26565.1 - 1.1e-07 31.3 13.6 2.2e-06 27.0 4.0 2.9 2 1 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 CCD26565.1 - 3.6e-06 27.1 11.1 3.6e-06 27.1 11.1 2.9 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 CCD26565.1 - 5.9e-06 26.3 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 DUF441 PF04284.13 CCD26565.1 - 0.12 12.4 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF441) Rbsn PF11464.8 CCD26565.1 - 0.25 11.1 0.8 10 5.9 0.1 2.5 2 0 0 2 2 2 0 Rabenosyn Rab binding domain FUSC PF04632.12 CCD26565.1 - 0.34 9.4 3.1 5.2 5.5 1.9 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family LIM_bind PF01803.16 CCD26566.1 - 1.2e-58 198.6 3.7 1.2e-58 198.6 3.7 4.3 3 2 1 4 4 4 2 LIM-domain binding protein PAPA-1 PF04795.12 CCD26567.1 - 6.3e-17 62.2 4.3 6.3e-17 62.2 4.3 3.7 2 1 1 3 3 3 1 PAPA-1-like conserved region RabGAP-TBC PF00566.18 CCD26568.1 - 1.7e-33 116.1 17.3 9e-31 107.2 8.6 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Flavodoxin_2 PF02525.17 CCD26569.1 - 2.7e-53 180.6 0.0 3.6e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CCD26569.1 - 2.1e-13 50.3 0.0 5.6e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Hpt PF01627.23 CCD26570.1 - 6e-11 42.5 0.1 9e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 Hpt domain MtlR PF05068.12 CCD26570.1 - 0.04 13.9 0.2 0.074 13.1 0.2 1.5 1 0 0 1 1 1 0 Mannitol repressor Hydrolase_6 PF13344.6 CCD26571.1 - 1.7e-27 95.4 0.0 4.3e-27 94.2 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCD26571.1 - 1.6e-14 54.7 0.0 2.2e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCD26571.1 - 4.9e-13 48.9 0.0 7.9e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 CCD26571.1 - 3.4e-07 30.5 0.2 0.00095 19.3 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 CCD26571.1 - 0.037 13.6 0.1 0.059 12.9 0.1 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Amidohydro_1 PF01979.20 CCD26573.1 - 2.2e-79 267.3 0.0 3e-79 266.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CCD26573.1 - 2.5e-07 30.5 0.1 6.8e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family G6PD_C PF02781.16 CCD26574.1 - 8.4e-105 350.1 0.0 1.2e-104 349.7 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CCD26574.1 - 5.7e-59 199.7 0.0 2e-58 197.9 0.0 1.9 3 0 0 3 3 3 1 Glucose-6-phosphate dehydrogenase, NAD binding domain RhoGAP PF00620.27 CCD26575.1 - 2e-36 125.1 1.9 1.8e-35 122.0 0.3 2.8 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 CCD26575.1 - 3.2e-24 84.9 55.1 1.9e-09 37.6 8.5 5.0 4 1 0 4 4 4 4 LIM domain DUF2757 PF10955.8 CCD26575.1 - 0.0049 17.1 5.0 0.2 11.9 0.1 3.8 3 0 0 3 3 3 2 Protein of unknown function (DUF2757) Siva PF05458.12 CCD26575.1 - 0.28 10.9 8.1 1.5 8.5 8.1 2.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) FAD-oxidase_C PF02913.19 CCD26576.1 - 1.7e-51 175.3 0.0 2.3e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CCD26576.1 - 4e-35 120.6 0.0 7.2e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ThylakoidFormat PF11264.8 CCD26576.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Thylakoid formation protein DUF5341 PF17276.2 CCD26578.1 - 3.9e-64 215.7 4.1 5.5e-64 215.2 4.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5341) Phage_holin_3_6 PF07332.11 CCD26578.1 - 0.16 12.0 0.7 1.4 9.0 0.0 2.1 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PDR_assoc PF08370.11 CCD26578.1 - 1.2 8.9 0.0 1.2 8.9 0.0 2.4 1 1 1 2 2 2 0 Plant PDR ABC transporter associated Helicase_C PF00271.31 CCD26579.1 - 5.2e-15 55.8 0.0 1.1e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCD26579.1 - 5.5e-06 26.3 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF5341 PF17276.2 CCD26580.1 - 2.1e-52 177.5 11.6 2.4e-52 177.4 11.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5341) Vac17 PF17321.2 CCD26580.1 - 0.11 11.9 0.1 0.11 11.9 0.1 1.0 1 0 0 1 1 1 0 Vacuole-related protein 17 Aa_trans PF01490.18 CCD26582.1 - 1.5e-75 254.4 37.4 1.8e-75 254.2 37.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PAT1 PF09770.9 CCD26583.1 - 1e-82 278.8 72.9 9.1e-42 143.4 0.0 5.6 2 2 1 3 3 3 3 Topoisomerase II-associated protein PAT1 JAB PF01398.21 CCD26583.1 - 0.075 13.0 0.0 1.6 8.7 0.0 2.7 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease P34-Arc PF04045.14 CCD26584.1 - 2.6e-93 312.1 2.6 3.3e-93 311.8 2.6 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc PP2C PF00481.21 CCD26585.1 - 4.4e-31 108.5 0.0 8.7e-30 104.2 0.0 2.4 1 1 1 2 2 2 1 Protein phosphatase 2C Med12 PF09497.10 CCD26586.1 - 9.4e-24 83.5 0.3 2.4e-23 82.2 0.3 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Thioredoxin PF00085.20 CCD26588.1 - 3.4e-26 91.2 0.2 1e-25 89.7 0.1 1.6 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 CCD26588.1 - 2.2e-06 27.9 0.1 0.00032 21.0 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CCD26588.1 - 2.5e-06 27.9 0.1 8e-06 26.3 0.1 1.8 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CCD26588.1 - 2.6e-05 24.0 0.0 3e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 CCD26588.1 - 0.00011 22.1 0.0 0.00013 21.9 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 CCD26588.1 - 0.00039 20.3 0.1 0.00064 19.6 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CCD26588.1 - 0.00089 19.0 0.1 0.13 11.9 0.1 2.2 1 1 1 2 2 2 1 Redoxin Phosducin PF02114.16 CCD26588.1 - 0.013 14.5 0.0 0.015 14.3 0.0 1.0 1 0 0 1 1 1 0 Phosducin OST3_OST6 PF04756.13 CCD26588.1 - 0.035 13.5 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Toxin-deaminase PF14424.6 CCD26588.1 - 0.062 13.4 0.1 0.089 12.9 0.1 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases KaiB PF07689.12 CCD26588.1 - 0.074 12.8 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 KaiB domain DUF953 PF06110.11 CCD26588.1 - 0.082 12.5 0.1 0.14 11.8 0.1 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Csm1_N PF18504.1 CCD26589.1 - 3.4e-27 94.6 6.1 3.4e-27 94.6 6.1 1.6 2 0 0 2 2 2 1 Csm1 N-terminal domain Csm1 PF12539.8 CCD26589.1 - 1.2e-21 77.1 0.1 2e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 TPR_MLP1_2 PF07926.12 CCD26589.1 - 0.00068 19.7 3.1 0.0012 18.9 3.1 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein ADIP PF11559.8 CCD26589.1 - 0.00076 19.6 4.8 0.0012 19.0 4.8 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 CCD26589.1 - 0.0011 19.4 3.4 0.0024 18.3 3.4 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF16 Spore_YpjB PF09577.10 CCD26589.1 - 0.0024 17.7 0.2 0.0037 17.1 0.2 1.3 1 0 0 1 1 1 1 Sporulation protein YpjB (SpoYpjB) Phage_GP20 PF06810.11 CCD26589.1 - 0.0027 17.5 3.4 0.0044 16.8 3.4 1.4 1 0 0 1 1 1 1 Phage minor structural protein GP20 SKA1 PF07160.12 CCD26589.1 - 0.009 15.9 4.2 0.094 12.6 2.8 2.0 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 1 S6OS1 PF15676.5 CCD26589.1 - 0.013 14.0 1.8 0.017 13.6 1.8 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family HAP1_N PF04849.13 CCD26589.1 - 0.044 13.0 5.6 0.062 12.5 5.6 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DegS PF05384.11 CCD26589.1 - 0.05 13.1 3.1 0.076 12.5 2.5 1.6 1 1 1 2 2 2 0 Sensor protein DegS DUF3450 PF11932.8 CCD26589.1 - 0.11 11.8 2.9 0.075 12.3 1.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF5094 PF17015.5 CCD26589.1 - 0.23 11.5 7.5 0.66 10.1 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5094) Sec2p PF06428.11 CCD26589.1 - 0.47 10.5 8.1 0.1 12.6 4.4 1.8 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p SlyX PF04102.12 CCD26589.1 - 0.51 11.0 5.3 0.18 12.5 2.3 1.9 2 0 0 2 2 2 0 SlyX NPV_P10 PF05531.12 CCD26589.1 - 0.8 10.2 6.1 3.1 8.3 4.8 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 CCD26589.1 - 0.83 10.1 5.5 8.7 6.8 5.1 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) zf-LYAR PF08790.11 CCD26590.1 - 1.4e-14 53.6 7.7 2.9e-14 52.7 7.7 1.5 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger PPL5 PF18168.1 CCD26590.1 - 0.024 14.0 5.9 0.028 13.7 5.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 zf-C2H2_jaz PF12171.8 CCD26590.1 - 0.027 14.8 4.4 0.23 11.8 0.6 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 CCD26590.1 - 0.05 13.6 3.1 2 8.5 0.1 2.3 2 0 0 2 2 2 0 XPA protein N-terminal zf_UBZ PF18439.1 CCD26590.1 - 0.087 12.4 1.6 11 5.8 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_4 PF13894.6 CCD26590.1 - 0.095 13.6 5.2 1.1 10.3 0.2 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger SLC12 PF03522.15 CCD26590.1 - 1.7 7.6 11.1 1.8 7.5 11.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 zf-C2H2 PF00096.26 CCD26590.1 - 3.2 8.4 5.9 1.9 9.1 1.1 2.6 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCD26590.1 - 6 7.5 9.2 21 5.7 3.9 3.2 1 1 1 2 2 2 0 Zinc-finger double domain Ndc1_Nup PF09531.10 CCD26590.1 - 6.3 5.3 6.4 7.6 5.1 6.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CCD26590.1 - 9.5 4.9 9.3 11 4.7 9.3 1.1 1 0 0 1 1 1 0 Presenilin Cofilin_ADF PF00241.20 CCD26591.1 - 1.1e-21 76.9 0.0 2.5e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.28 CCD26591.1 - 3.9e-15 55.2 1.0 9.9e-15 53.9 1.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCD26591.1 - 1.2e-12 47.4 0.3 2.8e-12 46.3 0.3 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCD26591.1 - 1.2e-05 24.8 0.0 2.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Flocculin_t3 PF13928.6 CCD26592.1 - 1.2e-10 41.7 69.3 1.9e-06 28.3 12.6 26.1 17 7 3 20 20 20 5 Flocculin type 3 repeat DUF866 PF05907.13 CCD26593.1 - 1.7e-43 148.2 3.2 5.2e-43 146.6 3.2 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Pkinase PF00069.25 CCD26594.1 - 1.4e-77 260.6 0.6 2.9e-77 259.6 0.6 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26594.1 - 2.9e-32 112.0 0.1 2.2e-21 76.3 0.2 2.4 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCD26594.1 - 2.1e-09 37.1 3.4 1.2e-06 28.1 0.1 3.7 2 1 0 3 3 3 2 Kinase-like Yeast-kill-tox PF09207.11 CCD26594.1 - 0.032 14.9 0.9 0.12 13.0 0.1 2.3 2 0 0 2 2 2 0 Yeast killer toxin MutS_V PF00488.21 CCD26595.1 - 5.5e-63 212.4 0.0 3.8e-62 209.7 0.0 2.3 2 0 0 2 2 2 1 MutS domain V MutS_I PF01624.20 CCD26595.1 - 1.3e-29 102.8 0.7 2.9e-29 101.6 0.1 2.0 2 0 0 2 2 2 1 MutS domain I MutS_III PF05192.18 CCD26595.1 - 1.2e-27 97.4 1.2 1.2e-27 97.4 1.2 2.4 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 CCD26595.1 - 4.4e-07 30.2 2.4 4.4e-07 30.2 2.4 2.2 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 CCD26595.1 - 3.6e-06 27.3 1.4 1.2e-05 25.7 0.0 2.6 3 1 0 3 3 3 1 MutS domain II U1snRNP70_N PF12220.8 CCD26595.1 - 0.54 10.9 0.0 0.54 10.9 0.0 3.3 3 1 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Not1 PF04054.15 CCD26596.1 - 3.7e-127 424.2 1.7 3.7e-127 424.2 1.7 3.8 4 0 0 4 4 4 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CCD26596.1 - 8.6e-85 283.7 4.5 4.7e-84 281.3 4.5 2.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_HEAT_N PF16419.5 CCD26596.1 - 2e-83 279.6 3.5 7.3e-83 277.7 3.5 2.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CNOT1_TTP_bind PF16417.5 CCD26596.1 - 2.3e-45 154.1 0.3 2.3e-45 154.1 0.3 3.4 4 0 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 CCD26596.1 - 2.3e-42 144.4 7.6 2.3e-42 144.4 7.6 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 CCD26596.1 - 1.2e-11 45.0 0.3 1.2e-11 45.0 0.3 5.7 7 1 0 7 7 7 1 CCR4-NOT transcription complex subunit 1 HEAT repeat KN_motif PF12075.8 CCD26596.1 - 0.15 11.9 0.2 9.2 6.2 0.0 2.7 2 0 0 2 2 2 0 KN motif CDC50 PF03381.15 CCD26597.1 - 4.3e-89 298.7 0.1 5.1e-89 298.5 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Y_phosphatase2 PF03162.13 CCD26598.1 - 1.6e-32 112.4 12.8 1.6e-23 83.1 2.6 2.8 3 0 0 3 3 3 2 Tyrosine phosphatase family NCE101 PF11654.8 CCD26599.1 - 8.4e-18 63.8 0.8 9.6e-18 63.6 0.8 1.1 1 0 0 1 1 1 1 Non-classical export protein 1 PI31_Prot_C PF08577.11 CCD26600.1 - 1.1e-09 39.3 5.8 2.5e-09 38.2 5.8 1.7 1 0 0 1 1 1 1 PI31 proteasome regulator DUF3215 PF11503.8 CCD26601.1 - 1.5e-18 66.4 0.0 2.3e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) PQ-loop PF04193.14 CCD26602.1 - 4.7e-23 80.7 17.6 4e-15 55.3 0.7 3.4 3 0 0 3 3 3 2 PQ loop repeat Pkinase PF00069.25 CCD26603.1 - 6.3e-63 212.6 0.0 2.2e-62 210.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26603.1 - 4.9e-34 117.8 0.0 1.6e-32 112.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD26603.1 - 7.4e-06 25.5 0.0 2.8e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Chordopox_A30L PF06015.12 CCD26603.1 - 0.0042 16.9 0.0 0.023 14.5 0.0 2.3 1 0 0 1 1 1 1 Chordopoxvirus A30L protein Kdo PF06293.14 CCD26603.1 - 0.057 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCD26603.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCD26603.1 - 0.4 9.4 0.0 0.4 9.4 0.0 2.8 3 1 0 3 3 3 0 Fungal protein kinase WD40 PF00400.32 CCD26604.1 - 9.5e-60 197.2 34.4 7.4e-10 39.3 0.1 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD26604.1 - 8e-20 71.0 5.1 8e-05 22.9 0.1 5.3 4 1 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 CCD26604.1 - 1.7e-09 38.0 0.0 3.1e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 CCD26604.1 - 3.5e-08 33.6 0.2 0.00033 20.6 0.0 3.3 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CCD26604.1 - 2.2e-05 23.3 3.4 3.9 6.0 0.0 5.1 4 2 2 6 6 6 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CCD26604.1 - 0.00098 18.2 0.2 2.2 7.2 0.0 4.0 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 CCD26604.1 - 0.0074 15.1 0.6 2.2 7.0 0.0 3.4 3 1 1 4 4 4 1 Nup133 N terminal like Nbas_N PF15492.6 CCD26604.1 - 0.0078 15.6 0.5 0.82 8.9 0.1 2.4 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 CCD26604.1 - 0.089 12.1 0.0 23 4.2 0.0 3.1 3 0 0 3 3 3 0 WD40-like domain Img2 PF05046.14 CCD26605.1 - 1.7e-24 85.9 0.4 2.9e-24 85.2 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Pro_isomerase PF00160.21 CCD26606.1 - 9.3e-24 84.5 0.0 1.5e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lipase_3 PF01764.25 CCD26607.1 - 6.2e-10 39.1 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CCD26607.1 - 0.0028 18.3 0.0 0.0044 17.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCD26607.1 - 0.007 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCD26607.1 - 0.012 15.3 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.12 CCD26607.1 - 0.027 14.4 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 CCD26607.1 - 0.089 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 CCD26607.1 - 0.12 12.1 0.0 0.38 10.4 0.0 1.8 1 1 1 2 2 2 0 PGAP1-like protein ANAPC4_WD40 PF12894.7 CCD26608.1 - 6.4e-06 26.4 0.0 8.1e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCD26608.1 - 0.02 15.7 0.2 2.5 9.1 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 CCD26609.1 - 1.9e-13 50.0 17.6 2e-13 49.9 10.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCD26609.1 - 4.7e-11 42.4 11.2 4.7e-11 42.4 11.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.27 CCD26609.1 - 3.5e-10 39.4 0.0 9.9e-10 37.9 0.0 1.9 1 0 0 1 1 1 1 SAP domain zf-C3HC4_3 PF13920.6 CCD26609.1 - 1.8e-09 37.3 11.3 1.1e-08 34.8 7.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCD26609.1 - 1.1e-08 35.2 13.3 4.8e-08 33.2 10.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CCD26609.1 - 1.4e-08 34.6 10.2 1.4e-08 34.6 10.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CCD26609.1 - 3.6e-08 33.4 14.7 8.1e-08 32.3 11.2 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CCD26609.1 - 4.8e-07 29.6 4.4 4.8e-07 29.6 4.4 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 CCD26609.1 - 8.3e-07 28.9 15.6 4.7e-06 26.5 10.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CCD26609.1 - 1.4e-06 28.1 12.2 2.8e-06 27.1 8.0 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CCD26609.1 - 2.5e-05 24.5 5.3 2.5e-05 24.5 5.3 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain U-box PF04564.15 CCD26609.1 - 0.0019 18.3 0.1 0.0082 16.3 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-RING_10 PF16685.5 CCD26609.1 - 0.0055 16.8 4.9 0.0055 16.8 4.9 2.1 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 CCD26609.1 - 0.045 13.6 6.3 0.085 12.7 1.9 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RelE PF06296.12 CCD26609.1 - 0.045 13.9 0.5 0.095 12.8 0.5 1.5 1 0 0 1 1 1 0 RelE toxin of RelE / RelB toxin-antitoxin system zf-Nse PF11789.8 CCD26609.1 - 0.058 13.2 10.0 0.13 12.1 5.5 2.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 CCD26609.1 - 0.24 11.3 10.6 1.5 8.7 0.1 3.5 4 0 0 4 4 3 0 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 CCD26609.1 - 0.74 9.9 3.6 0.7 10.0 1.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Forkhead PF00250.18 CCD26610.1 - 9.3e-33 112.3 2.5 2.3e-32 111.1 0.3 2.8 3 0 0 3 3 3 1 Forkhead domain G10 PF01125.17 CCD26611.1 - 7.7e-64 213.9 9.4 8.8e-64 213.7 9.4 1.0 1 0 0 1 1 1 1 G10 protein Ytp1 PF10355.9 CCD26612.1 - 4.1e-107 357.5 11.6 6.2e-107 356.9 11.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 CCD26612.1 - 2.4e-28 98.0 5.5 1.3e-27 95.7 5.5 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) LapA_dom PF06305.11 CCD26612.1 - 0.14 11.9 5.9 0.11 12.4 1.7 2.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TPR_2 PF07719.17 CCD26613.1 - 6.8e-10 38.3 0.1 4.7e-05 23.2 0.1 2.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CCD26613.1 - 7.5e-10 38.2 0.4 0.00037 20.2 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCD26613.1 - 3.7e-07 29.8 0.2 0.0066 16.6 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CCD26613.1 - 6.9e-06 25.6 0.3 1.7e-05 24.4 0.3 1.7 1 1 1 2 2 2 1 TPR repeat TPR_17 PF13431.6 CCD26613.1 - 4.4e-05 23.6 0.1 0.00023 21.3 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCD26613.1 - 0.0014 19.1 0.0 0.0036 17.8 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CCD26613.1 - 0.0031 18.1 0.0 0.0052 17.4 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCD26613.1 - 0.006 16.5 0.0 0.13 12.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CCD26613.1 - 0.0069 17.0 0.0 0.5 11.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCD26613.1 - 0.0073 16.6 0.0 4.8 7.6 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 CCD26613.1 - 0.017 15.1 0.3 0.029 14.4 0.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCD26613.1 - 0.026 14.6 0.1 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 CCD26613.1 - 0.052 14.4 0.0 1.2 10.2 0.0 2.4 2 1 1 3 3 2 0 Tetratricopeptide repeat DUF1771 PF08590.10 CCD26613.1 - 0.14 12.6 1.8 7.5 7.0 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1771) UPF0029 PF01205.19 CCD26614.1 - 7.2e-32 109.8 0.1 9.7e-32 109.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 CCD26614.1 - 7.2e-09 36.0 1.0 1.5e-08 34.9 1.0 1.6 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.26 CCD26614.1 - 0.13 11.9 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme WD40 PF00400.32 CCD26615.1 - 2.1e-40 135.9 15.9 2.4e-09 37.7 0.2 12.3 12 0 0 12 12 12 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD26615.1 - 1.4e-29 102.2 0.2 0.0003 21.0 0.0 9.3 3 2 7 10 10 10 8 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CCD26615.1 - 7.7e-23 80.9 0.0 1.2e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.11 CCD26615.1 - 6.3e-09 36.0 5.3 0.00018 21.5 0.1 5.9 4 1 2 6 6 6 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CCD26615.1 - 9.5e-09 35.0 3.6 0.13 11.5 0.1 5.1 4 2 0 5 5 5 3 WD40-like domain Ge1_WD40 PF16529.5 CCD26615.1 - 3.4e-06 26.3 2.7 0.28 10.1 0.1 5.4 3 2 3 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CCD26615.1 - 0.0028 17.0 0.4 3.3 7.0 0.0 3.7 3 1 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 CCD26615.1 - 0.037 12.9 0.1 5.1 5.9 0.2 2.4 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nop25 PF09805.9 CCD26615.1 - 7.9 6.9 6.0 15 6.0 6.0 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Atx10homo_assoc PF09759.9 CCD26616.1 - 3.8e-38 129.5 0.5 1.5e-37 127.5 0.5 2.1 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain DUF4829 PF16111.5 CCD26616.1 - 4.9 8.0 7.5 13 6.7 0.6 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4829) Thr_synth_N PF14821.6 CCD26617.1 - 1.3e-29 102.2 0.0 5.2e-29 100.3 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 CCD26617.1 - 2.2e-13 50.3 0.0 8.4e-13 48.4 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2683 PF10884.8 CCD26617.1 - 0.12 12.6 0.9 0.83 10.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) SWIB PF02201.18 CCD26618.1 - 0.0065 16.3 2.6 0.18 11.7 0.0 2.9 3 0 0 3 3 3 2 SWIB/MDM2 domain Secretin_N_2 PF07655.13 CCD26618.1 - 4 8.1 26.3 22 5.7 0.3 3.9 3 0 0 3 3 3 0 Secretin N-terminal domain SMYLE_N PF18615.1 CCD26618.1 - 8.9 5.8 8.0 0.55 9.7 0.4 2.4 3 0 0 3 3 3 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF1682 PF07946.14 CCD26619.1 - 5.8e-72 242.6 9.1 7.3e-72 242.3 9.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF4375 PF14300.6 CCD26619.1 - 0.16 12.2 3.8 0.54 10.5 3.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Ank_5 PF13857.6 CCD26620.1 - 7.2e-16 58.1 0.0 4.6e-12 45.9 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCD26620.1 - 2e-12 47.5 0.0 7.8e-10 39.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCD26620.1 - 7.4e-09 36.0 1.4 6.6e-08 32.9 0.1 2.9 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 CCD26620.1 - 3.5e-08 33.6 0.8 0.00049 20.4 0.1 3.3 2 1 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CCD26620.1 - 5.6e-08 32.4 0.0 0.00011 22.3 0.1 4.4 5 0 0 5 5 5 1 Ankyrin repeat Inositol_P PF00459.25 CCD26620.1 - 0.018 14.6 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family YfkB PF08756.10 CCD26620.1 - 0.096 12.5 0.1 0.35 10.7 0.0 1.8 1 1 1 2 2 2 0 YfkB-like domain MBOAT PF03062.19 CCD26621.1 - 3.8e-49 167.9 33.2 2.4e-48 165.3 33.2 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CCD26621.1 - 0.14 12.5 8.5 0.31 11.3 8.5 1.6 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family FCP1_C PF09309.10 CCD26621.1 - 1.3 8.9 7.9 1.9 8.3 7.9 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Macoilin PF09726.9 CCD26621.1 - 4.2 5.8 18.4 8.5 4.8 18.4 1.4 1 0 0 1 1 1 0 Macoilin family WBS_methylT PF12589.8 CCD26622.1 - 6.6e-12 46.0 6.9 1.2e-11 45.1 6.9 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 CCD26622.1 - 2.3e-11 44.2 0.0 8.3e-11 42.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCD26622.1 - 3.4e-11 43.6 0.0 7.6e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCD26622.1 - 4.1e-06 27.4 0.0 2.1e-05 25.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCD26622.1 - 8.3e-06 25.7 0.0 1.9e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCD26622.1 - 0.0001 22.2 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CCD26622.1 - 0.00069 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 CCD26622.1 - 0.00092 19.0 0.0 0.0042 16.9 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 CCD26622.1 - 0.0031 16.9 0.0 0.014 14.8 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase N6_N4_Mtase PF01555.18 CCD26622.1 - 0.0091 15.7 0.1 1.5 8.4 0.0 2.2 2 0 0 2 2 2 1 DNA methylase PrmA PF06325.13 CCD26622.1 - 0.014 14.8 0.2 0.06 12.7 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) PLRV_ORF5 PF01690.17 CCD26622.1 - 0.024 13.4 0.0 0.7 8.5 0.0 2.0 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein Methyltransf_32 PF13679.6 CCD26622.1 - 0.055 13.5 0.1 0.41 10.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 CCD26622.1 - 0.088 11.9 0.3 1.3 8.1 0.0 2.4 2 1 0 2 2 2 0 Ribosomal RNA adenine dimethylase FACT-Spt16_Nlob PF14826.6 CCD26622.1 - 0.17 11.7 1.4 0.22 11.3 0.6 1.5 2 0 0 2 2 2 0 FACT complex subunit SPT16 N-terminal lobe domain ADH_zinc_N PF00107.26 CCD26623.1 - 1.1e-13 51.3 0.0 2.4e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCD26623.1 - 0.0082 16.0 0.3 0.14 12.0 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CCD26623.1 - 0.096 13.7 0.0 0.16 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF4284 PF14112.6 CCD26623.1 - 0.26 12.2 3.8 0.58 11.1 1.5 2.1 1 1 1 2 2 2 0 Immunity protein 22 Ribosomal_L19 PF01245.20 CCD26624.1 - 2.6e-10 40.2 0.1 3.8e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 Peptidase_S8 PF00082.22 CCD26625.1 - 6.1e-27 94.7 0.0 8.2e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CCD26625.1 - 0.001 19.7 0.0 0.0023 18.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 ACC_central PF08326.12 CCD26626.1 - 8.5e-264 877.2 0.0 1.1e-263 876.8 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 CCD26626.1 - 5.2e-186 619.1 0.0 7.5e-186 618.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CCD26626.1 - 5.2e-51 173.1 0.0 1.1e-50 172.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CCD26626.1 - 8.4e-31 106.8 0.1 2.1e-30 105.5 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CCD26626.1 - 1.7e-20 73.1 0.0 8.2e-20 70.9 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CCD26626.1 - 4.5e-20 71.3 0.3 1.1e-19 70.0 0.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CCD26626.1 - 8.8e-05 22.3 0.1 0.012 15.4 0.0 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 CCD26626.1 - 0.021 14.8 0.0 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CCD26626.1 - 0.047 13.2 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus RnfC_N PF13375.6 CCD26626.1 - 0.075 13.0 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GxGYxYP_N PF16216.5 CCD26626.1 - 0.085 13.0 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal ATPgrasp_Ter PF15632.6 CCD26626.1 - 0.16 11.7 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF4667 PF15700.5 CCD26627.1 - 8.3e-58 196.4 104.4 4.9e-56 190.5 49.1 5.5 2 1 1 3 3 3 2 Domain of unknown function (DUF4667) PFK PF00365.20 CCD26628.1 - 1.6e-180 598.6 0.8 9e-100 333.7 1.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase Inp1 PF12634.7 CCD26629.1 - 2.2e-41 141.1 1.4 3.6e-41 140.4 0.0 2.1 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 Porin_3 PF01459.22 CCD26630.1 - 5.3e-87 291.7 0.1 6.3e-87 291.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin ERG2_Sigma1R PF04622.12 CCD26631.1 - 1.8e-92 308.4 1.6 2.1e-92 308.2 1.6 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein XPA_C PF05181.12 CCD26632.1 - 1.4e-22 79.4 0.1 2.7e-22 78.4 0.1 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 CCD26632.1 - 0.0014 18.6 0.7 0.0039 17.2 0.7 1.7 1 0 0 1 1 1 1 XPA protein N-terminal Cytochrome_C554 PF13435.6 CCD26632.1 - 2.4 9.2 5.7 11 7.0 0.6 3.4 2 1 1 3 3 3 0 Cytochrome c554 and c-prime Rot1 PF10681.9 CCD26633.1 - 1.7e-96 321.7 0.3 2e-96 321.5 0.3 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Microtub_bd PF16796.5 CCD26634.1 - 2.3e-19 69.8 3.2 2.3e-19 69.8 3.2 2.8 2 1 0 2 2 2 1 Microtubule binding ATG16 PF08614.11 CCD26634.1 - 0.0068 16.7 6.7 0.0068 16.7 6.7 2.6 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) LigD_N PF13298.6 CCD26634.1 - 0.023 15.0 0.2 8.1 6.8 0.0 2.9 3 0 0 3 3 3 0 DNA polymerase Ligase (LigD) NPV_P10 PF05531.12 CCD26634.1 - 5.6 7.5 31.0 0.85 10.1 3.0 5.2 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein V-SNARE_C PF12352.8 CCD26635.1 - 4.5e-20 71.7 2.5 4.5e-20 71.7 2.5 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 CCD26635.1 - 1.1e-15 57.8 4.6 1.1e-15 57.8 4.6 2.3 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 CCD26635.1 - 0.16 11.9 7.1 0.076 12.9 2.3 2.4 2 1 0 2 2 2 0 Sec20 FliJ PF02050.16 CCD26635.1 - 0.4 10.9 9.9 0.082 13.1 1.0 2.7 2 1 0 2 2 2 0 Flagellar FliJ protein YqjK PF13997.6 CCD26635.1 - 0.73 10.1 2.7 1.8 8.8 0.0 2.7 3 0 0 3 3 3 0 YqjK-like protein Glyco_hydro_63 PF03200.16 CCD26636.1 - 8.4e-07 28.1 15.4 7e-06 25.1 1.3 4.8 6 1 0 6 6 6 2 Glycosyl hydrolase family 63 C-terminal domain DUF2207 PF09972.9 CCD26636.1 - 0.011 14.5 0.0 0.023 13.5 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MTCP1 PF08991.10 CCD26638.1 - 1.9e-20 72.8 6.8 2.1e-20 72.7 6.8 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 CCD26638.1 - 0.0036 17.4 3.5 0.0036 17.4 3.5 1.9 2 0 0 2 2 2 1 CHCH domain COX17 PF05051.13 CCD26638.1 - 0.022 15.1 2.7 0.022 15.1 2.7 1.9 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 CCD26638.1 - 0.04 13.9 3.1 0.065 13.3 3.1 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Ribosomal_L36e PF01158.18 CCD26639.1 - 4.2e-37 126.3 4.0 4.7e-37 126.1 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TetR_C_9 PF14514.6 CCD26639.1 - 0.083 13.0 0.1 0.097 12.8 0.1 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_L28 PF00830.19 CCD26640.1 - 4.8e-20 71.5 1.0 9.8e-20 70.5 1.0 1.5 1 0 0 1 1 1 1 Ribosomal L28 family RabGAP-TBC PF00566.18 CCD26641.1 - 4.8e-23 81.9 0.6 4.8e-23 81.9 0.6 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DDE_Tnp_1_5 PF13737.6 CCD26642.1 - 0.0046 17.3 0.1 0.22 11.9 0.0 2.4 2 0 0 2 2 2 1 Transposase DDE domain DUF4911 PF16256.5 CCD26642.1 - 0.011 15.7 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) DotA PF11388.8 CCD26642.1 - 0.11 12.7 0.1 3.8 7.8 0.0 2.5 2 1 0 2 2 2 0 Phagosome trafficking protein DotA Fungal_trans PF04082.18 CCD26643.1 - 6.9e-14 51.5 13.6 6.9e-14 51.5 13.6 4.2 4 1 1 5 5 5 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD26643.1 - 2e-10 40.6 11.8 4e-10 39.7 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 CCD26643.1 - 1.8e-08 34.4 0.4 1.4e-07 31.5 0.4 2.7 1 0 0 1 1 1 1 Gal4-like dimerisation domain SUIM_assoc PF16619.5 CCD26643.1 - 0.51 10.4 18.6 0.073 13.1 7.2 3.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Helicase_Sgs1 PF11408.8 CCD26644.1 - 5.1e-26 90.5 0.1 2.5e-25 88.3 0.1 2.4 1 0 0 1 1 1 1 Sgs1 RecQ helicase Helicase_C PF00271.31 CCD26644.1 - 8.5e-22 77.6 0.2 1.1e-17 64.4 0.0 3.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.10 CCD26644.1 - 1.2e-21 76.7 0.3 2.8e-21 75.4 0.3 1.7 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 CCD26644.1 - 1.5e-21 77.0 0.1 5.7e-21 75.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 CCD26644.1 - 5e-16 59.2 9.4 1.8e-15 57.4 9.4 2.1 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 CCD26644.1 - 0.0002 21.4 0.0 0.0002 21.4 0.0 4.6 6 0 0 6 6 6 1 Type III restriction enzyme, res subunit HRDC PF00570.23 CCD26644.1 - 0.012 15.5 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 HRDC domain Rhodanese PF00581.20 CCD26644.1 - 0.4 11.2 5.9 2.6 8.6 0.1 4.0 4 0 0 4 4 4 0 Rhodanese-like domain PIN_2 PF10130.9 CCD26644.1 - 7.3 6.8 7.1 8.6 6.6 0.4 3.7 4 0 0 4 4 4 0 PIN domain NUDIX PF00293.28 CCD26645.1 - 1.5e-12 47.7 0.0 2.9e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 CCD26645.1 - 0.00013 21.5 0.0 0.00033 20.3 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.11 CCD26645.1 - 0.13 12.9 0.0 0.22 12.2 0.0 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain IBR PF01485.21 CCD26645.1 - 1.4 9.2 3.6 0.53 10.5 0.7 1.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain SCA7 PF08313.12 CCD26646.1 - 8.8e-30 102.4 0.5 8.8e-30 102.4 0.5 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain zf_C2H2_13 PF18508.1 CCD26646.1 - 3.5e-21 74.5 0.4 6.7e-21 73.6 0.4 1.5 1 0 0 1 1 1 1 Zinc finger domain GGDEF_2 PF17853.1 CCD26646.1 - 0.019 15.2 0.1 0.045 14.0 0.1 1.5 1 0 0 1 1 1 0 GGDEF-like domain Glycos_transf_1 PF00534.20 CCD26647.1 - 1.5e-34 119.0 0.0 2.1e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCD26647.1 - 6.8e-15 55.5 0.0 1.1e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CCD26647.1 - 3.8e-09 37.1 0.0 1.2e-08 35.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 CCD26647.1 - 0.0031 17.6 0.5 0.49 10.4 0.2 2.4 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus DEAD PF00270.29 CCD26648.1 - 1.1e-32 113.2 0.4 2.7e-32 111.9 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD26648.1 - 7.1e-17 61.8 3.3 7.6e-12 45.6 0.1 3.7 3 1 1 5 5 5 2 Helicase conserved C-terminal domain ResIII PF04851.15 CCD26648.1 - 2.2e-09 37.5 1.1 1.2e-08 35.2 0.1 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCD26648.1 - 0.0011 19.3 0.1 0.012 15.9 0.1 2.6 2 1 0 2 2 2 1 AAA domain Hyphal_reg_CWP PF11765.8 CCD26649.1 - 2e-85 286.7 17.0 2e-85 286.7 17.0 3.4 3 0 0 3 3 3 2 Hyphally regulated cell wall protein N-terminal PseudoU_synth_1 PF01416.20 CCD26650.1 - 3.6e-11 43.5 0.0 1.2e-09 38.6 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase DAP3 PF10236.9 CCD26651.1 - 2.3e-84 283.2 0.2 3e-84 282.8 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CCD26651.1 - 1.3e-05 25.7 0.0 2.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CCD26651.1 - 0.0061 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 CCD26651.1 - 0.0095 15.2 0.0 0.021 14.0 0.0 1.5 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 CCD26651.1 - 0.012 15.8 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CCD26651.1 - 0.017 15.1 0.0 0.084 12.8 0.0 2.2 2 0 0 2 2 2 0 NTPase T2SSG PF08334.11 CCD26651.1 - 0.022 14.8 0.0 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein G AAA_7 PF12775.7 CCD26651.1 - 0.062 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CCD26651.1 - 0.13 12.2 0.0 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 CCD26651.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CCD26651.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain mRNA_cap_enzyme PF01331.19 CCD26652.1 - 7.5e-59 198.8 1.0 9.8e-59 198.5 0.4 1.4 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CCD26652.1 - 2.9e-34 117.9 0.3 5.7e-34 117.0 0.3 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 CCD26652.1 - 1.3e-08 34.8 0.0 9.9e-06 25.3 0.0 2.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain BAH PF01426.18 CCD26653.1 - 2.5e-18 66.1 0.9 1.8e-17 63.3 0.1 2.6 2 0 0 2 2 2 1 BAH domain PHD PF00628.29 CCD26653.1 - 1.9e-14 53.2 53.8 8.3e-08 32.0 13.2 5.1 5 0 0 5 5 5 3 PHD-finger zf-HC5HC2H_2 PF13832.6 CCD26653.1 - 4.4e-13 49.4 8.6 4.4e-13 49.4 8.6 5.1 6 0 0 6 6 6 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CCD26653.1 - 3.5e-11 43.2 37.4 5.2e-08 33.0 7.3 5.0 4 0 0 4 4 4 3 PHD-like zinc-binding domain PHD_2 PF13831.6 CCD26653.1 - 4e-05 23.1 28.0 0.002 17.6 6.5 4.8 3 1 0 3 3 3 3 PHD-finger Myb_DNA-binding PF00249.31 CCD26653.1 - 9.4e-05 22.5 0.0 0.00025 21.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_1 PF00130.22 CCD26653.1 - 0.006 16.4 2.9 0.006 16.4 2.9 5.3 5 0 0 5 5 5 3 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CCD26653.1 - 0.33 11.3 57.4 0.095 13.0 4.5 6.3 6 0 0 6 6 6 0 C1 domain WAC_Acf1_DNA_bd PF10537.9 CCD26654.1 - 1.8e-35 121.5 0.5 8.2e-35 119.4 0.5 2.3 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 CCD26654.1 - 6.9e-11 42.5 0.0 6.9e-11 42.5 0.0 4.5 5 2 0 5 5 5 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 CCD26654.1 - 9e-11 41.9 1.5 1.2e-09 38.4 0.2 2.9 3 0 0 3 3 3 1 DDT domain WHIM1 PF15612.6 CCD26654.1 - 0.00028 20.3 0.1 0.0008 18.9 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Cyclin PF08613.11 CCD26655.1 - 4.6e-17 62.8 1.9 3e-16 60.2 1.9 2.2 1 1 0 1 1 1 1 Cyclin PMBR PF09373.10 CCD26655.1 - 0.01 15.9 0.0 2.5 8.4 0.0 3.1 2 0 0 2 2 2 0 Pseudomurein-binding repeat FtsJ PF01728.19 CCD26656.1 - 2.7e-50 170.9 0.0 3.5e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 CCD26656.1 - 0.0045 16.8 0.0 0.024 14.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCD26656.1 - 0.014 15.2 0.2 7.4 6.4 0.7 2.5 2 1 0 2 2 2 0 Methyltransferase domain LMP PF04778.12 CCD26656.1 - 0.082 12.8 0.2 0.082 12.8 0.2 1.8 3 0 0 3 3 3 0 LMP repeated region Coatomer_WDAD PF04053.14 CCD26657.1 - 2.9e-145 484.7 1.2 8.9e-145 483.1 0.4 2.1 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 CCD26657.1 - 4e-33 112.9 6.8 6.5e-06 26.8 0.0 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.8 CCD26657.1 - 2.2e-05 23.3 3.1 0.002 16.9 0.1 3.5 2 2 2 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 CCD26657.1 - 0.0025 17.8 0.0 16 5.6 0.0 5.0 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region MIT PF04212.18 CCD26657.1 - 0.0033 17.5 0.9 0.69 10.0 0.1 3.4 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 CCD26657.1 - 0.33 10.8 3.0 40 4.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1639 PF07797.14 CCD26658.1 - 0.13 12.3 1.5 0.84 9.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) MSP7_C PF12948.7 CCD26658.1 - 2.5 8.8 11.3 16 6.2 6.8 3.1 2 1 1 3 3 3 0 MSP7-like protein C-terminal domain TRP PF06011.12 CCD26659.1 - 6.9e-154 512.7 38.6 6.9e-154 512.7 38.6 1.6 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CCD26659.1 - 9.1e-41 139.5 0.9 1.5e-40 138.8 0.9 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 CCD26659.1 - 0.01 16.3 0.1 0.02 15.3 0.1 1.4 1 0 0 1 1 1 0 ML domain TMEMspv1-c74-12 PF11044.8 CCD26659.1 - 0.044 13.8 0.1 0.044 13.8 0.1 2.5 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein GCR1_C PF12550.8 CCD26660.1 - 2.9e-23 82.0 3.4 7.8e-23 80.6 3.4 1.8 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes CDC45 PF02724.14 CCD26660.1 - 0.27 9.5 33.9 0.77 8.0 33.9 1.8 1 0 0 1 1 1 0 CDC45-like protein CENP-I PF07778.11 CCD26661.1 - 1 8.0 3.6 2.1 7.0 3.6 1.4 1 0 0 1 1 1 0 Mis6 ARID PF01388.21 CCD26662.1 - 2.4e-18 66.6 0.1 1.2e-17 64.3 0.1 2.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjC PF02373.22 CCD26662.1 - 1.2e-15 58.0 3.6 2.5e-07 31.1 0.1 3.5 2 1 1 3 3 3 2 JmjC domain, hydroxylase PHD PF00628.29 CCD26662.1 - 1.1e-06 28.4 6.0 2.2e-06 27.5 6.0 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CCD26662.1 - 0.021 15.1 5.3 0.062 13.6 5.3 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain JmjN PF02375.17 CCD26662.1 - 0.053 13.5 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 jmjN domain C1_1 PF00130.22 CCD26662.1 - 0.31 11.0 3.8 0.79 9.7 3.8 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 CCD26662.1 - 1.3 9.2 5.5 3.6 7.7 5.5 1.8 1 0 0 1 1 1 0 PHD-finger GKAP PF03359.13 CCD26662.1 - 4.3 6.8 9.0 11 5.5 9.0 1.6 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Cation_efflux PF01545.21 CCD26663.1 - 3.5e-44 150.9 13.5 5.3e-44 150.4 13.5 1.3 1 0 0 1 1 1 1 Cation efflux family Polysacc_synt_4 PF04669.13 CCD26664.1 - 3.9e-20 72.2 2.8 1.2e-18 67.4 2.8 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis ABC_tran PF00005.27 CCD26665.1 - 1.1e-48 165.2 0.0 1.2e-25 90.6 0.0 4.2 3 2 0 3 3 3 2 ABC transporter SMC_N PF02463.19 CCD26665.1 - 6.9e-13 48.5 0.0 0.00089 18.8 0.0 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CCD26665.1 - 1.9e-12 47.7 7.1 0.013 15.4 0.0 4.8 2 2 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system Chromo PF00385.24 CCD26665.1 - 3.8e-11 42.7 1.3 1.1e-10 41.3 1.3 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.6 CCD26665.1 - 2.8e-07 30.2 0.3 0.022 14.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CCD26665.1 - 6.9e-07 29.3 0.0 0.018 15.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCD26665.1 - 1.7e-06 28.0 0.1 0.018 14.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 CCD26665.1 - 2.2e-05 25.0 0.1 0.0095 16.5 0.0 3.7 4 1 1 5 5 3 2 AAA domain AAA_22 PF13401.6 CCD26665.1 - 4.1e-05 23.9 0.0 0.67 10.2 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CCD26665.1 - 0.00015 22.2 0.1 4.7 7.6 0.0 4.1 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 CCD26665.1 - 0.00021 20.4 0.2 0.59 9.1 0.0 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 CCD26665.1 - 0.00024 21.4 0.1 0.42 10.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 CCD26665.1 - 0.00033 20.8 4.8 0.041 14.0 0.1 4.4 4 0 0 4 4 4 1 Helicase HerA, central domain AAA_18 PF13238.6 CCD26665.1 - 0.0005 20.6 0.1 0.63 10.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CCD26665.1 - 0.00065 20.1 0.0 1.7 9.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_16 PF13191.6 CCD26665.1 - 0.00069 20.0 0.1 0.19 12.1 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 CCD26665.1 - 0.0019 17.9 0.5 3.5 7.3 0.0 3.5 3 1 0 3 3 2 1 AAA domain AAA_27 PF13514.6 CCD26665.1 - 0.0022 17.6 0.0 1 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 CCD26665.1 - 0.003 17.3 6.8 0.52 10.0 0.0 3.8 3 1 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 CCD26665.1 - 0.0038 17.4 0.0 5.1 7.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CCD26665.1 - 0.0055 16.6 1.1 2.7 7.9 0.0 3.1 3 0 0 3 3 3 1 NACHT domain Dynamin_N PF00350.23 CCD26665.1 - 0.0067 16.5 0.1 0.47 10.5 0.0 3.1 2 1 0 2 2 2 1 Dynamin family DUF815 PF05673.13 CCD26665.1 - 0.011 14.9 0.1 3.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 CCD26665.1 - 0.013 15.5 0.1 5.6 7.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 CCD26665.1 - 0.037 14.2 0.0 13 6.0 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 CCD26665.1 - 0.042 13.6 0.0 2.1 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 CCD26665.1 - 0.06 13.1 0.0 7.7 6.2 0.0 2.6 2 0 0 2 2 2 0 MukB N-terminal NTPase_1 PF03266.15 CCD26665.1 - 0.061 13.2 0.1 7.6 6.4 0.1 2.9 3 0 0 3 3 3 0 NTPase Zeta_toxin PF06414.12 CCD26665.1 - 0.069 12.4 0.1 8.5 5.6 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 CCD26665.1 - 0.096 12.7 0.3 13 5.8 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thymidylate_kin PF02223.17 CCD26665.1 - 0.1 12.2 0.2 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase zf-H2C2_2 PF13465.6 CCD26668.1 - 9.7e-09 35.3 1.2 9.7e-09 35.3 1.2 3.4 4 0 0 4 4 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 CCD26668.1 - 3e-08 33.7 12.5 8.6e-05 22.8 1.7 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD26668.1 - 0.00017 22.1 11.8 0.0074 17.0 0.7 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCD26668.1 - 0.072 13.1 1.9 0.11 12.6 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger TMEM174 PF15029.6 CCD26668.1 - 0.085 12.6 3.9 0.058 13.1 0.9 2.0 2 0 0 2 2 2 0 Transmembrane protein 174 zf-MYST PF17772.1 CCD26668.1 - 0.099 12.3 0.2 0.27 10.9 0.1 1.8 1 1 0 1 1 1 0 MYST family zinc finger domain Hydin_ADK PF17213.3 CCD26668.1 - 0.21 11.9 3.8 1.4 9.2 3.6 2.3 2 1 1 3 3 3 0 Hydin Adenylate kinase-like domain zf-met PF12874.7 CCD26668.1 - 0.32 11.4 7.3 1.3 9.5 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 CCD26668.1 - 0.46 10.3 4.8 2 8.2 0.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain FAM176 PF14851.6 CCD26668.1 - 1.5 8.5 4.9 2.8 7.6 4.9 1.4 1 0 0 1 1 1 0 FAM176 family TipE PF16972.5 CCD26668.1 - 6.5 5.8 10.6 12 5.0 10.6 1.3 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE Syntaxin PF00804.25 CCD26669.1 - 6.8e-21 74.9 24.3 6.8e-21 74.9 24.3 2.5 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 CCD26669.1 - 1.1e-13 50.9 5.1 1.4e-13 50.6 3.0 2.4 2 0 0 2 2 2 1 SNARE domain Synaptobrevin PF00957.21 CCD26669.1 - 0.0048 16.6 2.4 0.0048 16.6 2.4 3.5 2 1 0 3 3 3 1 Synaptobrevin T2SSF PF00482.23 CCD26669.1 - 0.0085 16.0 0.2 0.028 14.4 0.2 1.9 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F DUF2207 PF09972.9 CCD26669.1 - 0.0086 14.9 0.1 0.0086 14.9 0.1 2.4 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) UPF0258 PF06789.12 CCD26669.1 - 0.032 14.3 4.1 0.27 11.3 0.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) DUF883 PF05957.13 CCD26669.1 - 1 10.0 6.1 0.82 10.3 0.7 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PBP1_TM PF14812.6 CCD26669.1 - 1.6 9.1 4.5 0.6 10.5 0.1 2.4 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2116 PF09889.9 CCD26669.1 - 2.8 8.0 5.7 1.6 8.7 0.9 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF745 PF05335.13 CCD26669.1 - 4.6 6.9 27.5 0.063 13.0 12.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF745) DUF5345 PF17280.2 CCD26669.1 - 6.4 6.8 7.2 0.67 10.0 0.4 2.9 2 2 2 4 4 4 0 Family of unknown function (DUF5345) RTP1_C1 PF10363.9 CCD26671.1 - 2.3e-30 105.1 0.2 1.2e-29 102.7 0.2 2.4 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 PMC2NT PF08066.12 CCD26671.1 - 0.82 10.4 13.7 0.37 11.5 3.8 4.3 1 1 2 3 3 3 0 PMC2NT (NUC016) domain HSP90 PF00183.18 CCD26672.1 - 4.3e-218 725.4 37.8 6e-218 724.9 37.8 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CCD26672.1 - 1.5e-14 54.4 0.0 3e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CCD26672.1 - 1.1e-09 38.3 0.0 3.7e-09 36.5 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Bacillus_HBL PF05791.11 CCD26672.1 - 0.16 11.8 6.1 0.11 12.3 3.1 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Tau95 PF09734.9 CCD26672.1 - 7.9 7.3 7.9 2.7 8.8 3.1 2.6 3 0 0 3 3 3 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain RINGv PF12906.7 CCD26673.1 - 6.8e-05 22.9 6.1 0.00015 21.8 6.1 1.6 1 0 0 1 1 1 1 RING-variant domain DiS_P_DiS PF06750.13 CCD26673.1 - 0.0032 17.5 0.0 0.0079 16.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial Peptidase A24 N-terminal domain zf-RING_2 PF13639.6 CCD26673.1 - 0.31 11.4 13.4 0.17 12.2 8.2 2.3 2 0 0 2 2 2 0 Ring finger domain FANCL_C PF11793.8 CCD26673.1 - 0.89 9.8 8.5 16 5.8 5.8 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain zinc-ribbons_6 PF07191.12 CCD26673.1 - 6.5 6.8 8.5 24 5.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbons Ribosomal_S17 PF00366.20 CCD26674.1 - 7.3e-23 80.5 1.3 7.3e-23 80.5 1.3 1.9 2 0 0 2 2 2 1 Ribosomal protein S17 GhoS PF11080.8 CCD26674.1 - 0.075 13.0 0.2 0.15 12.0 0.2 1.6 1 0 0 1 1 1 0 Endoribonuclease GhoS GDC-P PF02347.16 CCD26675.1 - 9.8e-191 634.2 0.0 2.1e-179 596.9 0.0 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein Pkinase PF00069.25 CCD26676.1 - 1.1e-23 84.0 0.0 2e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26676.1 - 3.3e-14 52.8 0.0 4.9e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCD26676.1 - 5.4e-08 32.0 0.0 8.6e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CCD26676.1 - 0.012 15.5 0.6 0.072 13.0 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L12 PF00542.19 CCD26677.1 - 4.5e-22 78.2 6.8 4.5e-22 78.2 6.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CCD26677.1 - 6.3e-09 35.4 5.0 6.3e-09 35.4 5.0 3.0 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain BLYB PF05289.11 CCD26677.1 - 0.015 15.5 1.0 3.3 8.0 0.2 2.6 2 1 1 3 3 3 0 Borrelia hemolysin accessory protein CSTF2_hinge PF14327.6 CCD26677.1 - 0.068 13.6 2.3 5.1 7.6 0.1 2.9 2 1 1 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 ENT PF03735.14 CCD26677.1 - 0.16 12.1 0.9 14 5.8 0.1 2.4 2 0 0 2 2 2 0 ENT domain RNA_POL_M_15KD PF02150.16 CCD26678.1 - 1.4e-17 63.3 4.4 1.4e-17 63.3 4.4 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 CCD26678.1 - 5.2e-13 48.6 2.3 5.2e-13 48.6 2.3 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DUF2387 PF09526.10 CCD26678.1 - 0.0083 16.2 4.4 1.2 9.3 0.2 2.4 2 1 0 2 2 2 2 Probable metal-binding protein (DUF2387) zf-UBP PF02148.19 CCD26678.1 - 0.016 15.6 4.3 0.21 12.0 0.5 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein DZR PF12773.7 CCD26678.1 - 0.049 13.7 7.4 1.5 8.9 0.4 2.6 2 1 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 CCD26678.1 - 0.084 12.9 11.2 0.85 9.7 3.1 2.7 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zinc_ribbon_10 PF10058.9 CCD26678.1 - 0.23 11.2 8.2 0.87 9.4 0.7 2.5 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Rubredoxin PF00301.20 CCD26678.1 - 0.74 9.9 4.7 27 4.9 0.2 3.3 4 0 0 4 4 4 0 Rubredoxin Nudix_N_2 PF14803.6 CCD26678.1 - 1.2 9.1 11.9 0.89 9.5 1.1 3.3 3 0 0 3 3 3 0 Nudix N-terminal AFT PF08731.11 CCD26679.1 - 1.8e-44 150.7 0.6 1.8e-44 150.7 0.6 4.0 4 1 0 4 4 4 1 Transcription factor AFT DBD_Tnp_Mut PF03108.15 CCD26679.1 - 0.055 13.5 0.7 11 6.1 0.0 3.1 3 0 0 3 3 3 0 MuDR family transposase HSF_DNA-bind PF00447.17 CCD26680.1 - 1.3e-29 102.6 2.9 6.5e-29 100.4 2.9 2.3 1 0 0 1 1 1 1 HSF-type DNA-binding MPS2 PF17060.5 CCD26681.1 - 3.7e-35 121.9 16.9 1.5e-33 116.6 16.9 2.5 1 1 0 1 1 1 1 Monopolar spindle protein 2 Fib_alpha PF08702.10 CCD26681.1 - 0.024 14.8 2.2 0.024 14.8 2.2 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Ribosomal_L30_N PF08079.12 CCD26682.1 - 9.8e-20 70.6 15.2 1.6e-19 69.9 15.2 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CCD26682.1 - 1.2e-19 70.0 2.9 2.7e-19 68.8 2.9 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e AA_permease_2 PF13520.6 CCD26683.1 - 5.5e-50 170.4 48.6 6.6e-50 170.2 48.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCD26683.1 - 3.1e-22 78.8 39.2 3.9e-22 78.5 39.2 1.0 1 0 0 1 1 1 1 Amino acid permease Insulin_TMD PF17870.1 CCD26683.1 - 1.9 8.6 0.0 1.9 8.6 0.0 3.4 4 0 0 4 4 4 0 Insulin receptor trans-membrane segment DEAD PF00270.29 CCD26684.1 - 6e-53 179.2 0.0 2e-52 177.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD26684.1 - 2.2e-34 118.1 0.1 7.4e-30 103.6 0.0 3.2 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CCD26684.1 - 3.9e-08 33.5 3.4 2e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CCD26684.1 - 7.3e-05 22.1 0.0 7.3e-05 22.1 0.0 2.3 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 CCD26684.1 - 0.00037 19.9 13.4 0.0024 17.3 0.0 2.5 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DUF4638 PF15472.6 CCD26684.1 - 0.011 15.5 11.6 0.025 14.3 11.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) UTP25 PF06862.12 CCD26684.1 - 0.021 13.6 0.0 0.021 13.6 0.0 3.1 3 1 1 4 4 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 CCD26684.1 - 0.14 12.5 0.5 0.89 9.8 0.5 2.3 1 1 0 1 1 1 0 AAA domain SR-25 PF10500.9 CCD26684.1 - 4.5 6.8 21.5 8.2 6.0 21.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CPSF100_C PF13299.6 CCD26684.1 - 8.5 6.5 10.7 41 4.3 9.3 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RP-C_C PF11800.8 CCD26684.1 - 9.2 6.3 6.1 15 5.6 6.1 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region KxDL PF10241.9 CCD26685.1 - 7.8e-21 74.2 2.8 7.8e-21 74.2 2.8 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein ANAPC4 PF12896.7 CCD26685.1 - 0.21 11.1 2.8 0.37 10.2 0.4 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Syntaxin-6_N PF09177.11 CCD26685.1 - 1.9 9.1 7.6 0.29 11.7 0.4 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal MPC PF03650.13 CCD26686.1 - 1.4e-18 67.0 0.0 1.6e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MINDY_DUB PF04424.13 CCD26687.1 - 4.4e-28 97.7 0.1 8.7e-28 96.7 0.1 1.5 1 0 0 1 1 1 1 MINDY deubiquitinase Pkinase PF00069.25 CCD26688.1 - 9.9e-18 64.4 0.5 1.7e-17 63.7 0.5 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26688.1 - 2e-07 30.6 0.0 3.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 CCD26689.1 - 0.03 14.6 0.0 0.3 11.4 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SNase PF00565.17 CCD26690.1 - 6.1e-21 74.9 0.0 1.4e-20 73.8 0.0 1.6 2 0 0 2 2 2 1 Staphylococcal nuclease homologue MAD PF05557.13 CCD26691.1 - 3e-34 118.4 77.2 4.3e-34 117.9 77.2 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein KELK PF15796.5 CCD26691.1 - 0.023 15.2 7.8 0.023 15.2 7.8 6.3 4 3 2 6 6 6 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4407 PF14362.6 CCD26691.1 - 0.42 9.9 43.5 0.015 14.7 4.4 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Trimer_CC PF08954.11 CCD26691.1 - 0.84 9.2 11.2 0.15 11.6 0.8 4.2 4 0 0 4 4 4 0 Trimerisation motif Pox_A_type_inc PF04508.12 CCD26691.1 - 2.1 8.3 10.5 11 6.0 0.2 5.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF883 PF05957.13 CCD26691.1 - 2.9 8.5 10.2 9 7.0 1.0 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) UQ_con PF00179.26 CCD26692.1 - 2.5e-17 62.8 0.0 3e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CCD26692.1 - 0.0028 17.9 0.0 0.0031 17.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain MF_alpha_N PF05436.11 CCD26693.1 - 1.3e-34 118.0 1.1 1.7e-34 117.6 1.1 1.2 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus MF_alpha PF04648.12 CCD26693.1 - 7.8e-28 95.6 47.2 1.1e-06 28.7 5.8 4.2 4 0 0 4 4 4 4 Yeast mating factor alpha hormone Apidaecin PF00807.17 CCD26693.1 - 0.92 9.7 11.6 20 5.4 0.3 4.2 4 0 0 4 4 4 0 Apidaecin ParA PF10609.9 CCD26695.1 - 2.5e-92 308.8 0.0 3e-92 308.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CCD26695.1 - 3.1e-11 43.4 0.0 5.1e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CCD26695.1 - 1.4e-06 28.3 0.7 4.7e-05 23.4 0.7 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 CCD26695.1 - 8.2e-05 22.0 0.0 0.00013 21.3 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CCD26695.1 - 0.0008 18.7 2.1 0.0039 16.4 0.4 2.4 1 1 2 3 3 3 1 Anion-transporting ATPase RsgA_GTPase PF03193.16 CCD26695.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase CBP_BcsQ PF06564.12 CCD26695.1 - 0.028 13.9 0.1 0.046 13.2 0.1 1.5 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ TF_Zn_Ribbon PF08271.12 CCD26695.1 - 0.029 13.9 0.2 0.073 12.6 0.2 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding AAA_26 PF13500.6 CCD26695.1 - 0.1 12.4 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CCD26695.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CCD26695.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Nucleoporin2 PF04096.14 CCD26696.1 - 4.5e-47 159.9 0.0 1.2e-46 158.5 0.0 1.8 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nup96 PF12110.8 CCD26696.1 - 1.1e-30 106.8 0.7 3e-29 102.1 0.7 2.4 1 1 0 1 1 1 1 Nuclear protein 96 Nucleoporin_FG PF13634.6 CCD26696.1 - 1.7e-09 38.4 91.7 4.8e-05 24.1 24.5 4.8 2 1 2 4 4 4 3 Nucleoporin FG repeat region Spc7 PF08317.11 CCD26697.1 - 4.7e-55 186.6 16.1 9.9e-55 185.6 16.1 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein UCH_1 PF13423.6 CCD26698.1 - 2.2e-65 221.4 5.6 3e-65 220.9 5.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 CCD26698.1 - 1.5e-20 74.4 0.0 3.5e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 Exonuclease ANAPC4_WD40 PF12894.7 CCD26698.1 - 0.016 15.5 0.0 0.53 10.6 0.0 3.0 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCD26698.1 - 0.048 14.5 1.9 42 5.2 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat Peptidase_C28 PF05408.11 CCD26698.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase CDC37_M PF08565.11 CCD26698.1 - 0.14 12.1 0.3 0.31 11.0 0.3 1.5 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain PHD PF00628.29 CCD26699.1 - 3e-10 39.8 6.0 6e-10 38.9 6.0 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CCD26699.1 - 0.42 10.2 6.0 0.71 9.5 6.0 1.4 1 0 0 1 1 1 0 PHD-finger RRM_1 PF00076.22 CCD26700.1 - 7.1e-13 48.2 0.0 1.6e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homeobox_KN PF05920.11 CCD26701.1 - 1.7e-19 69.4 0.8 4.7e-19 68.0 0.8 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CCD26701.1 - 1.3e-05 24.9 0.1 1.3e-05 24.9 0.1 2.1 2 0 0 2 2 2 1 Homeodomain RCC1 PF00415.18 CCD26702.1 - 4.3e-58 193.7 0.3 1.3e-08 35.4 0.1 7.4 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CCD26702.1 - 2e-38 129.4 18.1 4.1e-07 29.6 0.0 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Use1 PF09753.9 CCD26703.1 - 2.1e-13 50.6 3.9 2.8e-13 50.2 3.9 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Arteri_nsp7a PF16749.5 CCD26703.1 - 0.077 13.2 0.2 0.16 12.2 0.2 1.5 1 0 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha DUF4657 PF15552.6 CCD26703.1 - 0.3 10.6 4.4 0.42 10.1 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) SNF2_N PF00176.23 CCD26704.1 - 6.8e-75 252.0 0.4 6.8e-75 252.0 0.4 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 CCD26704.1 - 5.6e-37 126.3 1.2 5.6e-37 126.3 1.2 4.4 4 0 0 4 4 4 1 SLIDE HAND PF09110.11 CCD26704.1 - 2.1e-28 99.3 4.0 2.1e-28 99.3 4.0 6.1 6 1 0 6 6 6 1 HAND Helicase_C PF00271.31 CCD26704.1 - 1.1e-20 74.0 0.0 1e-19 70.9 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD26704.1 - 7.8e-10 39.0 0.0 7.8e-10 39.0 0.0 4.1 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCD26704.1 - 2.6e-05 24.1 0.0 7.3e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CCD26704.1 - 0.00095 18.4 0.3 0.00095 18.4 0.3 3.4 4 0 0 4 4 4 1 ERCC3/RAD25/XPB C-terminal helicase AAA_14 PF13173.6 CCD26704.1 - 0.025 14.6 0.2 0.24 11.4 0.1 2.9 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 CCD26705.1 - 1.2e-19 70.3 20.0 8e-05 23.3 0.6 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD26705.1 - 1.1e-11 44.8 1.2 0.0079 16.5 0.0 3.5 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCD26705.1 - 7.5e-05 21.8 0.6 4.6 6.1 0.0 4.0 2 1 0 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein YmzC PF14157.6 CCD26705.1 - 0.017 15.2 0.0 1.8 8.7 0.0 3.5 4 0 0 4 4 4 0 YmzC-like protein HD_3 PF13023.6 CCD26706.1 - 5.8e-37 127.2 0.2 7.4e-37 126.8 0.2 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CCD26706.1 - 1.6e-09 37.8 0.7 2e-09 37.4 0.7 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CCD26706.1 - 5.1e-05 23.5 0.0 8.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 HD domain Unstab_antitox PF09720.10 CCD26706.1 - 0.09 12.8 0.2 18 5.5 0.2 2.5 2 0 0 2 2 2 0 Putative addiction module component Ribosomal_L27A PF00828.19 CCD26707.1 - 5.7e-22 78.8 0.2 8.3e-22 78.2 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Sugar_tr PF00083.24 CCD26708.1 - 5.1e-81 272.8 11.9 6.7e-81 272.4 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD26708.1 - 3.7e-23 82.0 20.9 7.2e-19 67.9 5.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCD26708.1 - 2.5e-06 26.2 0.4 6.4e-06 24.9 0.4 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 CCD26708.1 - 0.00021 20.7 0.9 0.00049 19.5 0.9 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Ost5 PF05251.12 CCD26708.1 - 2.2 8.6 11.3 0.93 9.8 1.1 4.2 4 1 1 5 5 5 0 Oligosaccharyltransferase subunit 5 EF-hand_7 PF13499.6 CCD26709.1 - 9.6e-14 51.6 1.0 1.1e-09 38.6 0.5 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CCD26709.1 - 1.2e-10 41.0 2.3 5.8e-08 32.5 0.5 3.1 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CCD26709.1 - 5.2e-10 38.4 6.7 0.0003 20.5 0.1 3.7 3 1 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 CCD26709.1 - 1.1e-09 37.1 7.6 0.00081 18.8 0.1 3.7 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CCD26709.1 - 3.2e-07 30.6 0.0 0.0018 18.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 CCD26709.1 - 0.0044 17.9 0.0 0.0078 17.1 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_14 PF17959.1 CCD26709.1 - 0.0048 17.2 0.1 1.3 9.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CCD26709.1 - 0.016 14.7 7.4 4.3 7.0 0.3 3.6 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.7 CCD26709.1 - 0.14 12.1 0.6 0.78 9.7 0.1 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand PhetRS_B1 PF18262.1 CCD26709.1 - 0.41 10.9 3.3 3.5 7.9 0.5 2.7 1 1 1 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain DASH_Dad1 PF08649.10 CCD26710.1 - 0.026 14.7 0.2 0.095 12.9 0.1 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad1 DUF778 PF05608.12 CCD26711.1 - 0.18 12.1 1.1 0.21 11.9 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF778) Dicty_REP PF05086.12 CCD26711.1 - 0.42 8.5 9.2 0.42 8.5 9.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 CCD26711.1 - 1.4 8.9 13.2 1.9 8.5 13.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein CUE PF02845.16 CCD26712.1 - 0.0025 17.5 0.1 0.0079 15.9 0.1 2.0 1 0 0 1 1 1 1 CUE domain DUF3280 PF11684.8 CCD26712.1 - 0.035 14.5 1.0 0.64 10.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2380) WD40 PF00400.32 CCD26713.1 - 3.5e-13 49.8 9.3 0.00019 22.1 0.7 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD26713.1 - 1.1e-11 44.8 0.3 0.016 15.5 0.0 5.0 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCD26713.1 - 0.0077 16.1 0.1 0.21 11.5 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DASH_Dad3 PF08656.10 CCD26714.1 - 3.3e-26 91.2 0.8 4e-26 90.9 0.8 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 TAF6_C PF07571.13 CCD26715.1 - 4.3e-30 103.9 0.0 9.3e-30 102.8 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 CCD26715.1 - 1.3e-27 95.7 0.3 2.7e-27 94.7 0.3 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CCD26715.1 - 0.0027 18.1 0.8 0.0061 16.9 0.3 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF4 PF05236.14 CCD26715.1 - 0.0028 17.4 0.1 0.0047 16.7 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CENP-S PF15630.6 CCD26715.1 - 0.024 15.0 1.0 1 9.8 0.1 3.2 3 0 0 3 3 3 0 CENP-S protein DUF348 PF03990.14 CCD26715.1 - 0.027 14.2 0.0 0.27 11.0 0.0 2.5 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain TFIID-31kDa PF02291.15 CCD26715.1 - 0.028 14.5 0.2 0.064 13.3 0.2 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Sec7_N PF12783.7 CCD26715.1 - 0.65 9.9 5.7 30 4.5 2.7 3.3 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal SLD3 PF08639.10 CCD26716.1 - 2.8e-43 148.5 27.0 4.7e-30 104.9 20.0 2.1 1 1 1 2 2 2 2 DNA replication regulator SLD3 Sld3_N PF18523.1 CCD26716.1 - 8.8e-27 93.5 0.2 2.4e-26 92.1 0.2 1.8 1 0 0 1 1 1 1 Sld3 N-terminal domain KH_1 PF00013.29 CCD26717.1 - 6.5e-36 122.0 8.4 4.1e-13 49.0 2.7 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CCD26717.1 - 5.2e-08 32.7 0.1 0.024 14.5 0.0 3.6 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 CCD26717.1 - 2.8e-07 30.3 6.5 0.051 13.4 0.5 3.8 4 0 0 4 4 4 3 KH domain KH_5 PF13184.6 CCD26717.1 - 0.0086 16.1 1.7 6.4 6.9 0.1 3.5 3 0 0 3 3 3 1 NusA-like KH domain CSRNP_N PF16019.5 CCD26717.1 - 0.2 11.5 2.0 0.34 10.8 2.0 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus OPT PF03169.15 CCD26718.1 - 3.9e-158 527.9 19.9 4.4e-158 527.7 19.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Claudin_2 PF13903.6 CCD26718.1 - 1.8 8.3 13.3 0.034 13.9 0.7 3.5 3 1 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF4229 PF14012.6 CCD26718.1 - 10 6.3 15.3 1.3 9.2 8.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) CBS PF00571.28 CCD26720.1 - 5e-26 90.9 5.7 5.3e-12 46.0 0.1 4.2 4 0 0 4 4 4 4 CBS domain HTH_9 PF08221.11 CCD26720.1 - 0.094 12.8 1.3 1.7 8.8 0.1 3.0 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain ANAPC4_WD40 PF12894.7 CCD26721.1 - 7.5e-13 48.6 3.3 0.0017 18.6 0.2 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCD26721.1 - 1.3e-11 44.8 14.0 0.00036 21.3 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CCD26721.1 - 5.6e-07 28.8 0.1 9.7e-05 21.5 0.0 3.3 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Importin_rep_6 PF18829.1 CCD26722.1 - 0.07 13.3 0.5 0.35 11.0 0.1 2.1 2 0 0 2 2 2 0 Importin repeat 6 CENP-O PF09496.10 CCD26724.1 - 6.4e-05 23.0 0.0 0.00016 21.7 0.0 1.6 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component DivIC PF04977.15 CCD26724.1 - 0.016 15.0 0.8 0.016 15.0 0.8 1.8 2 0 0 2 2 2 0 Septum formation initiator ABC1 PF03109.16 CCD26725.1 - 2.8e-37 127.5 0.1 1.8e-36 124.9 0.0 2.2 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.25 CCD26725.1 - 0.0095 15.3 0.2 0.04 13.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain OB_NTP_bind PF07717.16 CCD26726.1 - 7.7e-23 80.7 0.0 3e-22 78.8 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CCD26726.1 - 2.5e-22 79.2 1.2 3.4e-22 78.8 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CCD26726.1 - 5.9e-11 42.7 0.0 1.8e-10 41.1 0.0 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCD26726.1 - 7.1e-10 38.9 0.2 1.2e-09 38.2 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCD26726.1 - 1.4e-06 28.6 0.1 4.2e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CCD26726.1 - 3.4e-05 23.6 0.1 8.9e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CCD26726.1 - 0.00017 22.0 0.1 0.00032 21.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 CCD26726.1 - 0.0004 20.4 0.1 0.00081 19.4 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 CCD26726.1 - 0.00051 19.8 0.0 0.00086 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CCD26726.1 - 0.0019 18.7 0.1 0.033 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CCD26726.1 - 0.0035 17.4 0.2 0.27 11.2 0.2 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 CCD26726.1 - 0.037 13.5 0.1 0.13 11.8 0.0 1.9 3 0 0 3 3 3 0 P-loop containing dynein motor region DUF2075 PF09848.9 CCD26726.1 - 0.04 13.2 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 CCD26726.1 - 0.043 12.9 0.0 0.088 11.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Rootletin PF15035.6 CCD26727.1 - 0.0063 16.6 0.7 0.0083 16.2 0.7 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Nab2 PF11517.8 CCD26728.1 - 3.5e-48 162.1 5.9 5.2e-48 161.5 5.9 1.2 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.6 CCD26728.1 - 1.5e-17 63.3 69.7 3.6e-05 24.1 2.6 7.1 7 0 0 7 7 7 5 RNA-binding, Nab2-type zinc finger Nab2p_Zf1 PF18260.1 CCD26728.1 - 5.8e-17 61.3 8.3 5.8e-17 61.3 8.3 3.3 3 0 0 3 3 3 1 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 DUF2508 PF10704.9 CCD26728.1 - 0.19 11.9 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) Ribosomal_S5 PF00333.20 CCD26729.1 - 1.9e-26 91.8 3.0 6e-26 90.2 2.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CCD26729.1 - 1.3e-22 79.0 0.0 2.3e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Mon1 PF03164.14 CCD26730.1 - 6.5e-144 479.9 3.2 8e-144 479.6 3.2 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 FA_desaturase PF00487.24 CCD26731.1 - 2.1e-17 63.8 16.9 2.1e-17 63.8 16.9 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 CCD26731.1 - 3.8e-13 49.4 0.0 7.6e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CBS PF00571.28 CCD26732.1 - 2e-22 79.4 4.5 1.5e-05 25.3 0.1 5.3 5 0 0 5 5 5 5 CBS domain UQ_con PF00179.26 CCD26734.1 - 9.3e-49 164.7 0.1 1.1e-48 164.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCD26734.1 - 0.018 14.7 0.0 0.031 14.0 0.0 1.3 1 1 0 1 1 1 0 Prokaryotic E2 family B Leuk-A4-hydro_C PF09127.11 CCD26734.1 - 0.11 12.6 0.1 1.4 9.1 0.1 2.0 1 1 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal BCDHK_Adom3 PF10436.9 CCD26735.1 - 3.9e-32 111.3 0.6 7.6e-32 110.4 0.6 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CCD26735.1 - 0.00099 19.6 0.0 0.041 14.4 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kinetochor_Ybp2 PF08568.10 CCD26738.1 - 1.6e-131 439.9 26.0 1.8e-131 439.7 26.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin DUF1151 PF06625.11 CCD26738.1 - 0.099 12.6 0.5 0.27 11.2 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) DASH_Duo1 PF08651.10 CCD26739.1 - 7e-27 93.0 1.1 1.5e-26 92.0 0.2 2.0 2 0 0 2 2 2 1 DASH complex subunit Duo1 CPSase_L_D2 PF02786.17 CCD26740.1 - 4.5e-83 277.9 0.2 7.7e-83 277.2 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 CCD26740.1 - 4.9e-68 228.8 0.0 8e-68 228.1 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 CCD26740.1 - 5.4e-38 129.9 0.0 1.1e-37 128.9 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CCD26740.1 - 1.3e-30 105.7 0.0 4.5e-30 103.9 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 CCD26740.1 - 3e-26 92.6 0.1 6.1e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 CCD26740.1 - 1.1e-18 66.8 2.4 1.1e-18 66.8 2.4 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CCD26740.1 - 1.3e-08 34.5 1.9 0.0042 16.9 0.2 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 CCD26740.1 - 5.2e-08 32.7 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CCD26740.1 - 2.7e-06 27.1 0.0 5.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 CCD26740.1 - 3.5e-05 23.9 0.0 9.1e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 CCD26740.1 - 0.0012 19.5 0.7 1.3 9.8 0.1 3.1 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 CCD26740.1 - 0.0024 17.1 0.2 0.15 11.3 0.1 2.5 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 CCD26740.1 - 0.0048 16.2 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 CCD26740.1 - 0.0091 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 CCD26740.1 - 0.017 14.7 0.0 0.12 12.0 0.0 2.1 1 1 0 1 1 1 0 RimK-like ATP-grasp domain RnfC_N PF13375.6 CCD26740.1 - 0.06 13.3 3.0 0.45 10.5 0.9 3.1 2 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 CCD26740.1 - 0.14 12.1 0.5 0.48 10.3 0.5 1.9 1 0 0 1 1 1 0 Glycine cleavage H-protein Gemini_coat PF00844.18 CCD26741.1 - 0.011 15.2 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family Crystall_4 PF17945.1 CCD26741.1 - 0.073 13.5 0.0 0.37 11.3 0.0 1.9 2 0 0 2 2 2 0 Beta/Gamma crystallin Med31 PF05669.12 CCD26743.1 - 9.3e-26 89.7 1.3 1.1e-25 89.4 1.3 1.2 1 0 0 1 1 1 1 SOH1 Scs3p PF10261.9 CCD26744.1 - 1.8e-70 237.3 9.2 2.4e-70 236.9 9.2 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM K-box PF01486.17 CCD26744.1 - 0.00068 19.8 0.8 0.0011 19.0 0.8 1.3 1 0 0 1 1 1 1 K-box region Aldo_ket_red PF00248.21 CCD26745.1 - 3.8e-59 200.3 0.0 4.4e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.21 CCD26745.1 - 0.1 12.6 0.1 0.26 11.3 0.1 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family MTHFR PF02219.17 CCD26746.1 - 1.9e-123 411.4 0.0 2.5e-123 411.0 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Cornichon PF03311.14 CCD26747.1 - 3e-48 163.2 10.3 3.5e-48 163.0 10.3 1.0 1 0 0 1 1 1 1 Cornichon protein Cellulase PF00150.18 CCD26748.1 - 1.1e-15 57.9 0.0 2e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) G_glu_transpept PF01019.21 CCD26749.1 - 4.8e-135 451.2 0.0 1.1e-134 450.1 0.0 1.5 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase zf-U1 PF06220.12 CCD26750.1 - 9.5e-19 66.9 5.5 2.5e-18 65.5 5.5 1.8 1 0 0 1 1 1 1 U1 zinc finger K_channel_TID PF07941.11 CCD26750.1 - 0.044 14.2 1.4 0.044 14.2 1.4 1.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Clr2 PF10383.9 CCD26750.1 - 0.068 13.9 0.8 2.5 8.9 0.0 2.3 2 1 0 2 2 2 0 Transcription-silencing protein Clr2 Ninjurin PF04923.12 CCD26751.1 - 0.04 13.9 3.7 0.032 14.2 2.3 1.6 1 1 1 2 2 2 0 Ninjurin TMEM154 PF15102.6 CCD26751.1 - 0.09 12.7 2.5 0.097 12.6 2.5 1.3 1 0 0 1 1 1 0 TMEM154 protein family ATP-synt_8 PF00895.20 CCD26751.1 - 0.11 13.0 0.5 0.11 13.0 0.5 2.2 2 0 0 2 2 2 0 ATP synthase protein 8 SLC3A2_N PF16028.5 CCD26751.1 - 0.39 10.3 1.3 0.59 9.7 1.3 1.3 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus Sigma_reg_N PF13800.6 CCD26751.1 - 1.6 9.1 6.3 0.17 12.2 1.1 2.1 3 0 0 3 3 3 0 Sigma factor regulator N-terminal TPR_1 PF00515.28 CCD26752.1 - 0.00042 20.0 0.1 0.44 10.4 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CCD26752.1 - 0.0015 18.5 0.0 3.1 8.1 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCD26752.1 - 0.01 16.0 0.1 0.54 10.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CCD26752.1 - 0.019 15.5 0.3 0.11 13.0 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short PF00106.25 CCD26753.1 - 1.4e-06 28.0 0.0 2.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 CCD26753.1 - 1.4e-06 27.9 0.0 2.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CCD26753.1 - 5.3e-05 23.2 0.0 0.00019 21.4 0.0 1.9 1 1 1 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 CCD26753.1 - 0.00049 19.6 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CCD26753.1 - 0.0045 16.0 0.0 0.0068 15.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CCD26753.1 - 0.0058 15.8 0.0 0.0094 15.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CCD26753.1 - 0.034 13.3 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.13 CCD26753.1 - 0.051 13.1 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 CCD26753.1 - 0.069 13.0 0.0 0.57 10.0 0.0 2.2 2 2 0 2 2 2 0 NAD(P)H-binding GTP_EFTU PF00009.27 CCD26754.1 - 2.2e-46 157.9 2.4 2.3e-46 157.8 1.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 CCD26754.1 - 4.5e-41 139.3 6.2 1e-40 138.2 6.2 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 CCD26754.1 - 8.2e-20 70.6 0.0 3.6e-19 68.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCD26754.1 - 2.8e-08 34.1 2.9 6.2e-08 32.9 1.3 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCD26754.1 - 5e-06 26.6 0.7 1.2e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 CCD26754.1 - 0.00093 18.7 0.1 0.0029 17.1 0.1 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit NAT PF04768.13 CCD26754.1 - 0.0031 17.2 0.2 0.0072 16.0 0.2 1.6 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase EFG_II PF14492.6 CCD26754.1 - 0.0093 16.0 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 CCD26754.1 - 0.0097 15.7 0.1 0.033 14.0 0.0 1.9 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain FeoB_N PF02421.18 CCD26754.1 - 0.11 12.1 1.0 0.27 10.7 0.3 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B Hus1 PF04005.12 CCD26755.1 - 5.6e-24 84.8 1.3 4.1e-19 68.8 0.3 2.2 2 0 0 2 2 2 2 Hus1-like protein DUF4340 PF14238.6 CCD26755.1 - 0.045 13.8 0.5 0.095 12.7 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4340) Ribosomal_S30 PF04758.14 CCD26756.1 - 8.3e-30 102.8 5.6 9.1e-30 102.6 5.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 GCIP PF13324.6 CCD26757.1 - 1.4e-40 139.6 7.7 1.9e-40 139.1 7.7 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 CCD26757.1 - 0.031 14.7 1.9 0.066 13.6 1.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Glyco_hydro_18 PF00704.28 CCD26758.1 - 1.1e-27 97.6 0.2 3.4e-27 96.0 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.13 CCD26758.1 - 0.0073 16.3 2.9 0.0073 16.3 2.9 3.3 3 0 0 3 3 3 1 Carbohydrate binding domain (family 19) ydhR PF08803.11 CCD26758.1 - 0.084 12.8 0.0 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 Putative mono-oxygenase ydhR Methyltransf_16 PF10294.9 CCD26759.1 - 2.2e-11 43.8 0.0 5.3e-11 42.6 0.0 1.6 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CCD26759.1 - 3.7e-06 26.9 0.0 5.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Sda PF08970.10 CCD26759.1 - 0.073 12.8 2.3 0.98 9.2 0.0 2.4 2 0 0 2 2 2 0 Sporulation inhibitor A PrmA PF06325.13 CCD26759.1 - 0.16 11.3 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ECH_1 PF00378.20 CCD26760.1 - 2e-17 63.4 0.0 1.9e-14 53.6 0.0 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CCD26760.1 - 2.5e-08 33.8 0.0 9.2e-08 31.9 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Syndecan PF01034.20 CCD26760.1 - 0.01 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SOP4 PF17081.5 CCD26760.1 - 0.016 14.7 0.6 0.037 13.5 0.3 1.6 2 0 0 2 2 2 0 Suppressor of PMA 1-7 protein DUF1640 PF07798.11 CCD26761.1 - 1.1e-15 58.2 7.4 1.1e-15 58.2 7.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) DsrC PF04358.13 CCD26761.1 - 0.0014 19.1 0.2 0.0042 17.6 0.2 1.8 1 0 0 1 1 1 1 DsrC like protein DUF4619 PF15398.6 CCD26761.1 - 0.01 15.4 3.6 0.01 15.4 3.6 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4619) RF-1 PF00472.20 CCD26762.1 - 1.7e-19 69.9 0.5 1.7e-19 69.9 0.5 2.1 1 1 1 2 2 2 1 RF-1 domain MDM10 PF12519.8 CCD26762.1 - 6.1 5.6 6.7 7.7 5.2 6.7 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Fungal_trans PF04082.18 CCD26763.1 - 2.6e-17 62.7 4.2 6.1e-17 61.5 4.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD26763.1 - 1.2e-07 31.7 7.8 3.1e-07 30.4 7.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CPSF73-100_C PF11718.8 CCD26764.1 - 2.2e-57 194.1 6.5 2.2e-57 194.1 6.5 1.7 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CCD26764.1 - 1.2e-30 106.0 0.0 2.5e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 CCD26764.1 - 6.4e-20 71.4 0.0 1.4e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 CCD26764.1 - 1.1e-19 71.2 0.6 1.8e-19 70.5 0.6 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 CCD26764.1 - 7.8e-18 64.2 0.0 1.7e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 CCD26764.1 - 1.6e-06 27.8 0.2 3.9e-05 23.2 0.2 2.6 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CCD26764.1 - 0.0041 17.0 0.2 0.023 14.6 0.2 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 CCD26764.1 - 0.02 14.1 0.0 0.062 12.5 0.0 1.8 2 0 0 2 2 2 0 Putative beta-lactamase-like family DEAD PF00270.29 CCD26765.1 - 3.4e-37 127.9 1.5 5.7e-37 127.2 1.5 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD26765.1 - 5.2e-31 107.3 0.3 2.8e-30 104.9 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD26765.1 - 4.5e-06 26.8 2.6 2.6e-05 24.3 0.1 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DnaI_N PF07319.11 CCD26765.1 - 0.0053 17.4 6.8 2.3 8.9 0.6 3.9 2 2 0 2 2 2 2 Primosomal protein DnaI N-terminus CDC45 PF02724.14 CCD26765.1 - 0.049 11.9 4.5 0.078 11.3 4.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Microtub_bind PF13931.6 CCD26765.1 - 4.2 7.8 10.9 2.4 8.5 3.6 2.7 2 1 0 2 2 2 0 Kinesin-associated microtubule-binding LSM PF01423.22 CCD26766.1 - 7.6e-18 64.0 0.5 1e-17 63.6 0.5 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CCD26766.1 - 0.074 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Hfq protein MCM PF00493.23 CCD26767.1 - 2.4e-104 347.3 0.0 4.1e-104 346.6 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCD26767.1 - 3.9e-36 123.7 0.0 8.7e-36 122.6 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCD26767.1 - 7.3e-28 96.8 1.9 2.4e-27 95.2 1.9 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CCD26767.1 - 1.4e-17 64.1 1.2 4.3e-17 62.6 1.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 CCD26767.1 - 2.1e-06 27.8 0.2 1.3e-05 25.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CCD26767.1 - 2.5e-06 27.0 0.1 0.00063 19.2 0.0 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CCD26767.1 - 0.00041 20.2 0.0 0.0036 17.2 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCD26767.1 - 0.029 14.1 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 CCD26767.1 - 0.039 14.4 0.2 0.32 11.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1822 PF08852.11 CCD26767.1 - 0.054 12.5 5.0 2.1 7.3 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1822) Pam16 PF03656.13 CCD26768.1 - 2.9e-06 27.3 0.1 3.8e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 CCD26768.1 - 0.00091 19.3 0.2 0.0015 18.6 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Response_reg PF00072.24 CCD26769.1 - 1.1e-19 70.7 0.1 3.5e-13 49.7 0.0 2.9 3 0 0 3 3 3 2 Response regulator receiver domain DUF3391 PF11871.8 CCD26769.1 - 5.1 7.6 6.1 0.89 10.1 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) Ssl1 PF04056.14 CCD26770.1 - 9.4e-89 296.3 0.0 1.4e-88 295.8 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 CCD26770.1 - 3.5e-25 88.0 11.0 3.5e-25 88.0 11.0 2.8 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 CCD26770.1 - 3.6e-14 53.3 0.0 8.7e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Macoilin PF09726.9 CCD26770.1 - 0.6 8.6 11.8 0.79 8.2 11.8 1.1 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 CCD26770.1 - 0.74 9.4 19.1 1.2 8.7 19.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DZR PF12773.7 CCD26770.1 - 1.8 8.7 22.3 0.8 9.8 6.7 3.3 2 1 0 2 2 2 0 Double zinc ribbon zf-HIT PF04438.16 CCD26770.1 - 2.5 8.0 21.3 0.89 9.5 0.9 3.2 3 0 0 3 3 3 0 HIT zinc finger IBR PF01485.21 CCD26770.1 - 8.8 6.6 20.6 0.036 14.3 6.4 2.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain MFS_1 PF07690.16 CCD26771.1 - 3.9e-36 124.7 22.1 1.1e-35 123.2 22.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily CRPA PF05745.11 CCD26771.1 - 0.37 10.8 4.1 8 6.5 0.1 2.8 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Aa_trans PF01490.18 CCD26772.1 - 4.1e-82 276.1 28.5 5e-82 275.8 28.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Mpp10 PF04006.12 CCD26773.1 - 5.4e-145 484.3 74.5 6.9e-145 483.9 74.5 1.0 1 0 0 1 1 1 1 Mpp10 protein Adaptin_N PF01602.20 CCD26776.1 - 1.5e-90 304.2 17.1 2.1e-90 303.8 17.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CCD26776.1 - 3.8e-12 46.6 4.5 4.8e-11 43.0 0.2 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCD26776.1 - 3.5e-06 27.3 0.0 0.12 12.8 0.0 3.2 2 1 0 2 2 2 2 HEAT repeats Arm PF00514.23 CCD26776.1 - 0.0019 18.2 0.1 14 5.9 0.0 4.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat T_hemolysin PF12261.8 CCD26776.1 - 0.0049 16.6 0.0 0.0092 15.8 0.0 1.3 1 0 0 1 1 1 1 Thermostable hemolysin ENTH PF01417.20 CCD26776.1 - 0.041 13.9 0.9 1 9.4 0.0 3.1 2 1 1 3 3 3 0 ENTH domain Symplekin_C PF12295.8 CCD26776.1 - 1.2 9.2 6.3 12 5.9 0.0 3.7 2 1 1 3 3 3 0 Symplekin tight junction protein C terminal Abhydro_lipase PF04083.16 CCD26777.1 - 4.5e-17 61.4 0.0 1.1e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CCD26777.1 - 9.4e-05 22.2 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCD26777.1 - 0.072 12.3 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 POC3_POC4 PF10448.9 CCD26778.1 - 4.5e-27 94.8 0.1 5.1e-27 94.7 0.1 1.1 1 0 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 Fil_haemagg PF05594.14 CCD26778.1 - 0.13 12.8 0.2 0.38 11.3 0.1 1.8 2 0 0 2 2 2 0 Haemagluttinin repeat SBDS PF01172.18 CCD26779.1 - 9.1e-33 112.2 2.4 1.6e-32 111.4 2.4 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 CCD26779.1 - 2.1e-29 101.9 2.4 2.1e-29 101.9 2.4 1.9 2 0 0 2 2 2 1 SBDS protein C-terminal domain Cytadhesin_P30 PF07271.11 CCD26779.1 - 0.0084 15.7 0.2 0.015 14.9 0.2 1.3 1 0 0 1 1 1 1 Cytadhesin P30/P32 COX16 PF14138.6 CCD26780.1 - 1.5e-30 105.5 0.1 1.5e-30 105.5 0.1 2.1 2 1 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 DUF5314 PF17241.2 CCD26781.1 - 3.9e-69 232.2 3.2 7.1e-69 231.4 3.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5314) Asp PF00026.23 CCD26781.1 - 2.2e-05 24.1 0.6 6.3e-05 22.5 0.0 2.0 2 1 1 3 3 3 1 Eukaryotic aspartyl protease DLIC PF05783.11 CCD26782.1 - 3.3e-07 29.5 0.1 5e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) SYS1 PF09801.9 CCD26783.1 - 8.4e-49 165.4 11.7 9.8e-49 165.2 11.7 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network PNP_UDP_1 PF01048.20 CCD26784.1 - 1.2e-33 116.4 0.0 1.4e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NPCC PF08058.11 CCD26785.1 - 5.3e-31 107.4 0.3 8.4e-31 106.7 0.3 1.3 1 0 0 1 1 1 1 Nuclear pore complex component NIF PF03031.18 CCD26786.1 - 8.9e-53 178.2 0.1 1.6e-52 177.5 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sof1 PF04158.14 CCD26787.1 - 3.6e-26 91.3 16.4 9e-26 90.0 16.4 1.7 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 CCD26787.1 - 9e-26 89.6 9.7 9.8e-06 26.2 0.0 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD26787.1 - 1.7e-07 31.4 0.5 0.03 14.6 0.0 4.6 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCD26787.1 - 0.00021 20.4 1.3 0.14 11.0 0.1 3.2 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 CCD26787.1 - 0.0006 19.8 0.5 0.11 12.5 0.0 3.8 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Zn_clus PF00172.18 CCD26788.1 - 3e-06 27.2 10.5 3e-06 27.2 10.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rab_bind PF16704.5 CCD26788.1 - 0.12 12.4 0.3 0.28 11.2 0.3 1.6 1 0 0 1 1 1 0 Rab binding domain Longin PF13774.6 CCD26789.1 - 1.9e-20 72.7 0.1 3.1e-20 72.0 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 CCD26789.1 - 5.3e-15 55.0 0.0 9e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.12 CCD26789.1 - 0.0059 16.6 0.7 0.011 15.8 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Phi-29_GP16_7 PF06720.11 CCD26789.1 - 0.044 13.6 0.4 0.076 12.8 0.4 1.3 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 DcpS_C PF11969.8 CCD26790.1 - 9.3e-36 122.8 0.4 2.7e-35 121.3 0.1 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 CCD26790.1 - 8.4e-34 116.5 0.1 1.4e-33 115.8 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.23 CCD26790.1 - 0.066 14.0 0.1 0.54 11.0 0.0 2.4 3 0 0 3 3 3 0 HIT domain DUF4187 PF13821.6 CCD26791.1 - 8.6e-19 67.1 0.6 1.5e-18 66.3 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Cnd1 PF12717.7 CCD26792.1 - 1.1e-51 175.1 9.9 1.1e-43 149.1 1.7 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 CCD26792.1 - 2.4e-50 170.6 2.1 2.4e-50 170.6 2.1 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 CCD26792.1 - 3.8e-13 48.5 2.7 0.015 15.5 0.0 5.8 5 0 0 5 5 5 4 HEAT repeat HEAT_2 PF13646.6 CCD26792.1 - 1.7e-09 37.9 0.0 0.0044 17.4 0.0 3.4 2 1 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 CCD26792.1 - 2.1e-06 28.1 0.4 8.3 7.0 0.0 5.0 5 0 0 5 5 5 2 HEAT-like repeat RTP1_C1 PF10363.9 CCD26792.1 - 0.00082 19.5 2.5 0.14 12.4 0.1 3.9 2 1 1 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 YtzH PF14165.6 CCD26792.1 - 1.7 9.1 8.5 1.6 9.2 0.1 4.0 4 0 0 4 4 4 0 YtzH-like protein SGTA_dimer PF16546.5 CCD26793.1 - 8.8e-15 54.2 0.1 3e-14 52.5 0.1 2.0 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 CCD26793.1 - 2.4e-14 52.2 12.0 0.00025 20.9 0.3 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CCD26793.1 - 9.1e-13 47.4 6.4 0.0015 18.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCD26793.1 - 2.1e-10 40.1 11.5 5.2e-06 26.1 1.2 4.0 2 1 2 4 4 4 3 TPR repeat TPR_8 PF13181.6 CCD26793.1 - 2.2e-06 27.4 7.0 0.0012 18.8 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCD26793.1 - 0.00071 19.8 5.0 0.0059 16.9 1.0 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCD26793.1 - 0.00093 19.4 1.8 5.3 7.6 0.3 4.2 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CCD26793.1 - 0.0069 16.2 2.9 0.053 13.4 0.2 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CCD26793.1 - 0.0077 17.0 0.1 37 5.5 0.0 3.6 1 1 2 3 3 3 0 Tetratricopeptide repeat GerD PF17898.1 CCD26793.1 - 0.0094 15.9 3.8 0.025 14.5 0.0 2.8 3 0 0 3 3 3 1 Spore germination GerD central core domain TPR_19 PF14559.6 CCD26793.1 - 0.01 16.3 2.3 0.044 14.3 0.2 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCD26793.1 - 0.014 16.0 0.3 0.081 13.6 0.1 2.4 1 1 0 2 2 2 0 Tetratricopeptide repeat STI1 PF17830.1 CCD26793.1 - 0.082 12.9 0.9 0.24 11.4 0.9 1.8 1 0 0 1 1 1 0 STI1 domain Fis1_TPR_C PF14853.6 CCD26793.1 - 0.093 12.8 3.1 0.16 12.0 0.1 3.1 3 1 1 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 CCD26793.1 - 0.11 13.0 0.1 6.6 7.2 0.0 2.4 1 1 1 2 2 2 0 Bacterial transcriptional activator domain DUF3856 PF12968.7 CCD26793.1 - 0.14 12.2 2.5 5.4 7.1 1.0 3.2 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_7 PF13176.6 CCD26793.1 - 0.25 11.4 8.8 3 8.1 0.0 3.7 3 2 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 CCD26793.1 - 5.5 7.1 10.6 0.18 11.9 1.3 3.4 3 2 0 3 3 2 0 MIT (microtubule interacting and transport) domain WPP PF13943.6 CCD26793.1 - 9.8 6.6 7.5 2 8.9 2.9 2.2 2 0 0 2 2 2 0 WPP domain Fcf1 PF04900.12 CCD26794.1 - 2e-33 114.7 1.4 4.5e-33 113.6 1.4 1.6 1 0 0 1 1 1 1 Fcf1 DNA_ligase_A_M PF01068.21 CCD26795.1 - 7e-51 172.8 0.1 1.1e-50 172.1 0.1 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CCD26795.1 - 5.2e-24 85.5 0.2 1.4e-22 80.8 0.0 2.7 3 0 0 3 3 3 1 DNA ligase N terminus BRCT_2 PF16589.5 CCD26795.1 - 1.2e-18 67.3 0.1 1.5e-10 41.3 0.0 3.6 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 CCD26795.1 - 2.9e-09 37.4 0.1 8.9e-09 35.9 0.1 1.9 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 CCD26795.1 - 7.3e-07 29.5 0.3 2.3e-05 24.7 0.0 3.0 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.19 CCD26795.1 - 0.00078 19.3 2.5 0.22 11.3 0.8 2.8 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain Acetyltransf_7 PF13508.7 CCD26796.1 - 9.5e-07 29.2 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CCD26796.1 - 2.9e-05 24.3 0.0 0.00076 19.7 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCD26796.1 - 6.3e-05 22.9 0.0 0.0026 17.7 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CCD26796.1 - 0.057 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 CCD26796.1 - 0.076 13.0 0.0 8.3 6.5 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_3 PF13302.7 CCD26796.1 - 0.095 13.4 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_S8 PF00082.22 CCD26797.1 - 1.3e-29 103.5 0.8 3.1e-29 102.2 0.8 1.6 1 1 0 1 1 1 1 Subtilase family zf-RRN7 PF11781.8 CCD26798.1 - 3e-09 36.4 1.4 3e-09 36.4 1.4 1.9 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Clat_adaptor_s PF01217.20 CCD26799.1 - 1.3e-54 184.0 1.7 1.7e-54 183.6 1.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-UBR PF02207.20 CCD26800.1 - 1.2e-11 44.6 11.9 3.4e-11 43.2 11.9 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) tRNA-synt_1b PF00579.25 CCD26801.1 - 5.6e-77 258.9 0.0 7.2e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HlyIII PF03006.20 CCD26802.1 - 1.8e-71 240.4 20.1 2.4e-71 240.0 20.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Fungal_trans PF04082.18 CCD26804.1 - 2.9e-35 121.6 0.0 8.2e-35 120.1 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD26804.1 - 8.9e-10 38.5 9.7 1.7e-09 37.7 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAGK_cat PF00781.24 CCD26805.1 - 7.5e-27 93.4 0.0 1.6e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RNase_J_C PF17770.1 CCD26805.1 - 1.3 10.2 4.3 22 6.2 0.3 3.4 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain Ras PF00071.22 CCD26806.1 - 6.1e-57 191.8 0.5 7.5e-57 191.5 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD26806.1 - 9.2e-38 129.1 0.2 1.7e-37 128.3 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD26806.1 - 1.5e-15 57.1 0.6 1.8e-15 56.9 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CCD26806.1 - 1.6e-06 28.1 0.1 0.057 13.3 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CCD26806.1 - 7.2e-06 26.1 0.1 2.7e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 CCD26806.1 - 3.4e-05 23.3 0.0 8.6e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CCD26806.1 - 0.0004 19.8 0.3 0.00051 19.5 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CCD26806.1 - 0.00058 19.4 0.2 0.0049 16.4 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CCD26806.1 - 0.00085 19.1 1.0 0.0067 16.2 1.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CCD26806.1 - 0.0054 16.3 0.0 0.0088 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 CCD26806.1 - 0.013 15.3 0.3 0.022 14.5 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CCD26806.1 - 0.028 14.7 0.0 0.055 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain DLIC PF05783.11 CCD26806.1 - 0.029 13.2 0.3 0.14 11.0 0.2 2.0 2 1 1 3 3 3 0 Dynein light intermediate chain (DLIC) ATPase_2 PF01637.18 CCD26806.1 - 0.031 14.2 0.2 0.06 13.3 0.1 1.5 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 CCD26806.1 - 0.036 14.5 0.0 0.053 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 CCD26806.1 - 0.096 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 CCD26806.1 - 0.11 12.4 0.5 0.23 11.5 0.5 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Red1 PF07964.11 CCD26807.1 - 3.8e-76 256.9 82.4 3.8e-76 256.9 82.4 2.9 2 2 1 3 3 3 1 Rec10 / Red1 Ribosomal_S28e PF01200.18 CCD26808.1 - 2.6e-32 110.6 2.5 2.8e-32 110.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e S_layer_C PF05124.12 CCD26808.1 - 0.16 11.9 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region XLF PF09302.11 CCD26809.1 - 3.3e-05 24.1 10.3 7.6e-05 23.0 10.3 1.7 1 1 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Musclin PF11037.8 CCD26809.1 - 0.014 15.3 0.3 0.014 15.3 0.3 1.6 2 0 0 2 2 2 0 Insulin-resistance promoting peptide in skeletal muscle DUF4679 PF15728.5 CCD26809.1 - 0.02 14.0 6.0 0.029 13.4 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) GATase_6 PF13522.6 CCD26811.1 - 4.4e-12 46.4 0.0 1.3e-11 44.9 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CCD26811.1 - 5.5e-09 36.0 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 CCD26811.1 - 5.5e-08 32.5 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 CCD26811.1 - 0.00038 19.4 0.0 0.00058 18.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ABC_membrane PF00664.23 CCD26812.1 - 2.9e-39 135.4 10.6 4.1e-39 134.9 10.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CCD26812.1 - 7.8e-33 113.9 0.0 1.5e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CCD26812.1 - 6.2e-08 32.3 0.2 0.00017 21.1 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CCD26812.1 - 0.00089 19.7 0.0 0.0031 17.9 0.0 1.8 2 1 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.6 CCD26812.1 - 0.0014 18.3 0.1 0.0044 16.7 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 CCD26812.1 - 0.0048 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 CCD26812.1 - 0.0073 16.6 0.0 0.032 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CCD26812.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 CCD26812.1 - 0.015 14.1 0.1 0.37 9.5 0.0 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF815 PF05673.13 CCD26812.1 - 0.027 13.6 0.0 0.056 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 CCD26812.1 - 0.032 13.9 0.0 0.089 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF3987 PF13148.6 CCD26812.1 - 0.052 12.5 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_24 PF13479.6 CCD26812.1 - 0.08 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CCD26812.1 - 0.58 10.6 0.1 0.58 10.6 0.1 2.8 2 1 0 2 2 1 0 AAA domain Epimerase PF01370.21 CCD26813.1 - 3.2e-18 66.1 0.1 4.1e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCD26813.1 - 2e-15 56.5 0.5 2.7e-15 56.1 0.5 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CCD26813.1 - 1.5e-10 40.7 0.5 8.3e-10 38.3 0.5 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 CCD26813.1 - 1.1e-08 34.8 0.8 2.8e-06 26.9 0.4 2.7 2 1 0 2 2 2 2 short chain dehydrogenase NAD_binding_10 PF13460.6 CCD26813.1 - 8.7e-08 32.3 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CCD26813.1 - 1.6e-07 31.1 0.1 2.3e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 CCD26813.1 - 4.2e-05 23.5 0.1 8.3e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CCD26813.1 - 5.4e-05 22.5 0.6 0.00056 19.1 0.5 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CCD26813.1 - 0.00058 19.5 0.6 0.0043 16.6 0.3 2.1 2 0 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.17 CCD26813.1 - 0.0013 19.3 0.4 0.0072 16.9 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.6 CCD26813.1 - 0.012 15.2 0.7 0.028 14.0 0.4 1.8 2 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase CBM_21 PF03370.13 CCD26814.1 - 1.6e-23 83.0 12.4 1.6e-23 83.0 12.4 2.9 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) Myb_DNA-bind_6 PF13921.6 CCD26814.1 - 0.00055 20.1 1.0 0.0025 18.1 0.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain CBM53 PF16760.5 CCD26814.1 - 0.011 16.3 11.5 0.011 16.3 11.5 4.3 2 1 0 2 2 2 0 Starch/carbohydrate-binding module (family 53) BUD22 PF09073.10 CCD26814.1 - 4.8 6.4 20.7 6.5 6.0 12.2 2.7 2 1 0 2 2 2 0 BUD22 Lyase_1 PF00206.20 CCD26815.1 - 3.1e-115 384.9 0.1 4.3e-115 384.4 0.1 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CCD26815.1 - 5.4e-25 87.6 0.0 2.5e-24 85.4 0.1 2.1 2 0 0 2 2 2 1 Fumarase C C-terminus dCMP_cyt_deam_1 PF00383.23 CCD26816.1 - 1.2e-08 34.7 0.0 2.2e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCD26816.1 - 1.1e-05 25.2 0.0 3.7e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 MafB19-like deaminase E1-E2_ATPase PF00122.20 CCD26817.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 E1-E2 ATPase RT_RNaseH_2 PF17919.1 CCD26818.1 - 2e-29 101.5 0.0 3.5e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCD26818.1 - 1.5e-27 95.9 0.0 4.6e-27 94.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CCD26818.1 - 6.8e-22 78.1 0.0 1.5e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 CCD26818.1 - 0.069 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain DUF3589 PF12141.8 CCD26819.1 - 4.3e-82 276.3 3.7 3.7e-79 266.6 3.7 2.5 1 1 0 1 1 1 1 Beta-mannosyltransferases RNA12 PF10443.9 CCD26820.1 - 6.1e-170 565.7 0.2 3.8e-169 563.1 0.1 2.2 2 1 1 3 3 3 1 RNA12 protein RRM_1 PF00076.22 CCD26820.1 - 1.8e-07 30.9 0.0 4.1e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 CCD26820.1 - 0.00028 20.9 0.3 0.0021 18.0 0.3 2.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CCD26820.1 - 0.00037 20.5 1.0 0.023 14.7 0.0 3.1 4 0 0 4 4 4 1 AAA domain USP7_C2 PF14533.6 CCD26821.1 - 5.1e-55 186.4 4.7 5.1e-55 186.4 4.7 2.9 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 CCD26821.1 - 8.1e-45 153.3 1.9 1.5e-44 152.4 1.9 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 CCD26821.1 - 4.7e-32 111.2 4.7 1.1e-31 110.0 0.1 2.6 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 CCD26821.1 - 7.1e-22 78.4 0.1 3.8e-21 76.0 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UN_NPL4 PF11543.8 CCD26821.1 - 0.0034 17.8 0.4 1.1 9.8 0.2 3.2 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 Glyco_hydro_17 PF00332.18 CCD26822.1 - 3.5e-09 36.7 3.6 1.3e-08 34.9 3.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 RAP1 PF07218.11 CCD26822.1 - 0.55 8.5 8.9 0.71 8.1 8.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Mucin PF01456.17 CCD26822.1 - 0.56 10.2 26.5 1.5 8.8 26.5 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein SWI-SNF_Ssr4 PF08549.10 CCD26822.1 - 1.9 7.0 6.7 2.4 6.7 6.7 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Dicty_REP PF05086.12 CCD26822.1 - 3.2 5.6 4.9 3.9 5.3 4.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NUDE_C PF04880.13 CCD26822.1 - 5 7.6 6.8 8.4 6.8 6.8 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Glucan_synthase PF02364.15 CCD26823.1 - 0 1321.8 7.6 0 1321.8 7.6 2.1 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CCD26823.1 - 1.7e-42 144.8 1.9 1.2e-41 142.0 1.9 2.4 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF3671 PF12420.8 CCD26823.1 - 0.015 15.3 0.7 0.015 15.3 0.7 4.1 4 1 0 4 4 4 0 Protein of unknown function Glyco_hydro_72 PF03198.14 CCD26824.1 - 3.9e-146 486.3 10.7 3.9e-146 486.3 10.7 1.4 2 0 0 2 2 2 1 Glucanosyltransferase X8 PF07983.13 CCD26824.1 - 2.6e-28 98.5 4.9 9.5e-28 96.7 4.9 2.1 1 0 0 1 1 1 1 X8 domain Apt1 PF10351.9 CCD26824.1 - 4.4 6.0 10.5 6.3 5.5 10.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Importin_rep_6 PF18829.1 CCD26825.1 - 1.4e-44 150.7 2.4 1.4e-44 150.7 2.4 2.9 2 0 0 2 2 2 1 Importin repeat 6 Importin_rep_4 PF18808.1 CCD26825.1 - 3.4e-31 107.4 0.6 3.4e-31 107.4 0.6 4.1 4 0 0 4 4 3 1 Importin repeat HEAT_EZ PF13513.6 CCD26825.1 - 1.1e-22 80.1 4.0 5.6e-11 42.7 0.0 7.9 7 1 1 8 8 7 3 HEAT-like repeat Importin_rep_5 PF18816.1 CCD26825.1 - 4.9e-21 74.8 1.5 2.3e-20 72.6 0.1 3.0 3 0 0 3 3 2 1 Importin repeat HEAT PF02985.22 CCD26825.1 - 1.4e-19 68.5 3.4 0.021 15.0 0.0 9.7 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 CCD26825.1 - 5.5e-15 55.5 0.2 3.4e-06 27.4 0.0 6.7 4 2 2 6 6 6 4 HEAT repeats RIX1 PF08167.12 CCD26825.1 - 4.9e-10 39.4 4.5 2.7e-05 24.0 0.5 4.9 4 1 1 5 5 5 3 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 CCD26825.1 - 5.8e-09 35.0 1.3 0.0032 16.1 0.4 4.6 3 1 1 4 4 4 4 Adaptin N terminal region Cnd1 PF12717.7 CCD26825.1 - 7.7e-07 29.3 2.6 0.68 10.0 0.0 5.8 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CCD26825.1 - 8.6e-07 28.7 1.3 0.0059 16.2 0.4 4.7 6 0 0 6 6 6 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 CCD26825.1 - 2.4e-06 28.0 0.3 0.017 15.7 0.0 5.2 4 2 2 6 6 5 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 CCD26825.1 - 8.2e-06 25.8 7.3 0.042 13.7 0.6 6.6 5 2 1 7 7 7 1 Domain of unknown function (DUF3385) MMS19_C PF12460.8 CCD26825.1 - 9e-06 25.1 19.6 0.0012 18.0 6.7 4.7 4 2 3 7 7 7 3 RNAPII transcription regulator C-terminal ParcG PF10274.9 CCD26825.1 - 7.3e-05 23.0 0.8 0.056 13.6 0.0 3.6 3 0 0 3 3 3 1 Parkin co-regulated protein Arm PF00514.23 CCD26825.1 - 0.0002 21.3 8.5 1.6 8.9 0.3 6.3 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 CCD26825.1 - 0.00092 19.4 0.5 3.6 7.8 0.0 4.1 2 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 CCD26825.1 - 0.022 14.5 0.0 0.25 11.0 0.0 2.9 4 0 0 4 4 4 0 DNA alkylation repair enzyme IFRD PF05004.13 CCD26825.1 - 0.36 9.9 7.2 0.095 11.8 0.3 3.6 5 0 0 5 5 5 0 Interferon-related developmental regulator (IFRD) eIF-3c_N PF05470.12 CCD26826.1 - 1.6e-164 548.6 18.8 2.4e-127 425.8 6.6 2.2 1 1 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CCD26826.1 - 2.7e-10 40.7 2.8 6.2e-10 39.5 0.3 3.0 3 1 0 3 3 3 1 PCI domain Methyltrn_RNA_3 PF02598.17 CCD26827.1 - 6.7e-77 258.8 0.0 8.3e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase IPP-2 PF04979.14 CCD26828.1 - 7.8e-22 78.4 13.7 7.8e-22 78.4 13.7 2.1 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) YfhO PF09586.10 CCD26828.1 - 1.8 6.7 3.2 1.7 6.7 3.2 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SURF4 PF02077.15 CCD26829.1 - 2.1e-95 319.3 15.0 2.6e-95 319.0 15.0 1.0 1 0 0 1 1 1 1 SURF4 family DUF4395 PF14340.6 CCD26829.1 - 0.013 15.9 3.9 0.013 15.9 3.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4395) DUF4233 PF14017.6 CCD26829.1 - 0.098 13.0 13.3 0.27 11.6 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) ELP6 PF09807.9 CCD26830.1 - 0.0037 16.7 0.0 0.006 16.0 0.0 1.4 1 1 0 1 1 1 1 Elongation complex protein 6 MSP PF01716.18 CCD26830.1 - 0.06 12.5 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide DUF3336 PF11815.8 CCD26831.1 - 3.8e-23 81.7 0.0 9.5e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CCD26831.1 - 3.9e-08 33.7 0.0 7.8e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase DUF4652 PF15525.6 CCD26831.1 - 0.02 14.7 0.1 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) Proteasome PF00227.26 CCD26832.1 - 1.8e-45 154.8 0.0 2.1e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCD26832.1 - 7.2e-12 44.8 0.1 1.3e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature MFS_1 PF07690.16 CCD26833.1 - 3.7e-07 29.4 46.4 2.7e-05 23.3 44.4 3.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CCD26833.1 - 2e-06 26.5 26.9 4.6e-06 25.3 26.3 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CCD26833.1 - 0.00035 19.5 7.8 0.00035 19.5 7.8 3.2 3 1 1 4 4 4 1 Sugar (and other) transporter DUF2530 PF10745.9 CCD26833.1 - 0.062 13.5 0.3 0.062 13.5 0.3 4.2 5 1 1 6 6 6 0 Protein of unknown function (DUF2530) DUF1673 PF07895.11 CCD26833.1 - 1.9 8.2 9.2 4.9 6.8 0.2 4.0 3 2 1 4 4 4 0 Protein of unknown function (DUF1673) AA_permease PF00324.21 CCD26834.1 - 8.3e-122 407.2 41.8 1e-121 406.9 41.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD26834.1 - 2e-32 112.6 43.3 2.8e-32 112.1 43.3 1.2 1 0 0 1 1 1 1 Amino acid permease Pet100 PF09803.9 CCD26834.1 - 0.062 13.8 1.4 0.22 12.0 0.1 2.2 2 0 0 2 2 2 0 Pet100 RVT_2 PF07727.14 CCD26835.1 - 1e-90 303.6 0.0 2.1e-90 302.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CCD26835.1 - 7.1e-19 68.2 0.1 3e-18 66.1 0.1 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 CCD26835.1 - 4.6e-11 42.4 0.0 4.6e-11 42.4 0.0 2.6 3 0 0 3 3 2 1 GAG-pre-integrase domain DUF5314 PF17241.2 CCD26835.1 - 4.5e-10 39.5 0.1 1.1e-09 38.3 0.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5314) Asp PF00026.23 CCD26835.1 - 0.00016 21.2 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease FlxA PF14282.6 CCD26835.1 - 0.0041 17.1 5.2 0.014 15.4 5.2 1.8 1 0 0 1 1 1 1 FlxA-like protein FapA PF03961.13 CCD26835.1 - 0.072 11.7 0.4 0.21 10.1 0.3 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A LPP PF04728.13 CCD26835.1 - 0.36 11.2 3.9 14 6.2 0.2 2.7 1 1 1 2 2 2 0 Lipoprotein leucine-zipper CLZ PF16526.5 CCD26835.1 - 0.37 11.2 3.1 1.6 9.1 0.1 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FliJ PF02050.16 CCD26835.1 - 0.38 11.0 1.0 0.85 9.9 1.0 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein ZapB PF06005.12 CCD26835.1 - 0.47 10.9 3.2 25 5.4 0.1 2.5 2 0 0 2 2 2 0 Cell division protein ZapB SlyX PF04102.12 CCD26835.1 - 0.68 10.6 3.3 34 5.1 3.0 2.6 1 1 0 1 1 1 0 SlyX DUF5082 PF16888.5 CCD26835.1 - 1.9 8.7 6.8 5.8 7.2 0.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 CCD26835.1 - 7.3 7.1 7.9 1.2 9.7 2.5 2.5 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Methyltransf_11 PF08241.12 CCD26836.1 - 8.7e-17 61.6 0.0 1.4e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCD26836.1 - 1.1e-14 54.9 0.0 2.2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCD26836.1 - 6.9e-12 46.0 0.0 1.2e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCD26836.1 - 3.1e-09 36.9 0.0 4.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCD26836.1 - 2.6e-08 33.8 0.0 4.6e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CCD26836.1 - 2.4e-07 30.3 0.0 3.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 CCD26836.1 - 0.0056 16.5 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 CCD26836.1 - 0.0076 15.6 0.0 0.018 14.3 0.0 1.6 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 CCD26836.1 - 0.052 12.5 0.0 0.087 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_15 PF09445.10 CCD26836.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PAS_3 PF08447.12 CCD26836.1 - 0.13 12.5 0.0 4.5 7.6 0.0 2.5 1 1 0 2 2 2 0 PAS fold MTS PF05175.14 CCD26836.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PI-PLC-X PF00388.19 CCD26837.1 - 1.1e-51 174.2 0.1 5.2e-51 172.0 0.1 2.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CCD26837.1 - 1.3e-38 131.8 0.2 1.3e-38 131.8 0.2 2.5 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 CCD26837.1 - 2.1e-08 34.5 1.3 7.1e-08 32.8 1.3 2.0 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.32 CCD26837.1 - 0.00081 18.8 0.4 0.22 11.2 0.0 3.4 3 0 0 3 3 3 1 EF hand C2 PF00168.30 CCD26837.1 - 0.022 15.0 0.0 0.13 12.6 0.0 2.3 2 0 0 2 2 2 0 C2 domain EF-hand_7 PF13499.6 CCD26837.1 - 0.18 12.3 2.8 1.6 9.2 0.4 3.0 2 0 0 2 2 2 0 EF-hand domain pair RrnaAD PF00398.20 CCD26839.1 - 1.2e-74 250.8 0.0 1.4e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CCD26839.1 - 1.1e-06 29.3 0.0 2.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCD26839.1 - 0.00011 22.8 0.0 0.0003 21.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CCD26839.1 - 0.00041 20.2 0.0 0.00072 19.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 CCD26839.1 - 0.0012 18.2 0.0 0.0041 16.5 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.16 CCD26839.1 - 0.0037 17.1 0.1 0.67 9.8 0.0 2.3 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.16 CCD26839.1 - 0.0092 15.7 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 CCD26839.1 - 0.017 15.0 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CCD26839.1 - 0.026 15.3 0.0 0.054 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CCD26839.1 - 0.036 13.6 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_28 PF02636.17 CCD26839.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AAA_lid_4 PF17864.1 CCD26839.1 - 0.094 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 RuvB AAA lid domain Methyltransf_18 PF12847.7 CCD26839.1 - 0.11 12.4 0.0 6.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain KAR9 PF08580.10 CCD26840.1 - 2.9e-47 161.6 23.7 4.2e-47 161.1 23.7 1.2 1 0 0 1 1 1 1 Yeast cortical protein KAR9 ABC_membrane PF00664.23 CCD26841.1 - 3.5e-52 177.8 5.2 4.8e-52 177.3 5.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CCD26841.1 - 2e-34 119.0 0.4 9.7e-34 116.8 0.0 2.4 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 CCD26841.1 - 0.00018 21.0 0.0 0.021 14.2 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 CCD26841.1 - 0.0034 17.2 0.0 0.2 11.3 0.0 3.0 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_29 PF13555.6 CCD26841.1 - 0.0047 16.6 0.1 0.019 14.7 0.1 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 CCD26841.1 - 0.023 14.7 0.0 0.073 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCD26841.1 - 0.027 14.7 0.0 0.19 12.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 CCD26841.1 - 0.032 14.7 0.0 0.31 11.4 0.0 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 CCD26841.1 - 0.054 13.3 0.4 0.28 10.9 0.0 2.3 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.6 CCD26841.1 - 0.089 13.2 0.0 0.42 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF948 PF06103.11 CCD26841.1 - 0.13 12.6 0.5 0.49 10.7 0.0 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ATP-synt_Eps PF04627.13 CCD26842.1 - 1.1e-19 70.2 0.8 1.3e-19 69.9 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Kelch_4 PF13418.6 CCD26843.1 - 5.3e-30 103.2 9.4 5.7e-07 29.4 0.0 7.1 6 2 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 CCD26843.1 - 8.1e-29 99.3 6.5 2.9e-08 33.8 0.0 7.2 7 0 0 7 7 7 4 Galactose oxidase, central domain DUF4110 PF13422.6 CCD26843.1 - 7.5e-25 86.8 0.0 7.5e-25 86.8 0.0 4.2 4 1 1 5 5 5 2 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 CCD26843.1 - 1.4e-21 76.0 12.3 1.4e-08 34.7 0.1 5.8 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 CCD26843.1 - 7.5e-14 51.1 16.4 2.9e-05 23.5 0.4 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 CCD26843.1 - 2.1e-12 46.7 8.7 0.001 19.0 0.2 6.3 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 CCD26843.1 - 7.2e-12 44.8 13.8 0.052 13.5 0.5 6.4 6 0 0 6 6 6 4 Kelch motif Mpp10 PF04006.12 CCD26843.1 - 0.12 10.8 44.1 0.025 13.1 9.1 3.1 3 0 0 3 3 3 0 Mpp10 protein SAGA-Tad1 PF12767.7 CCD26843.1 - 1 9.0 11.1 2.1 8.0 1.8 2.5 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit NDC10_II PF16787.5 CCD26844.1 - 3.4e-87 292.5 11.1 1.5e-86 290.4 11.1 2.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 CCD26844.1 - 3.4e-16 59.3 4.1 3.9e-16 59.1 1.9 2.4 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Cwf_Cwc_15 PF04889.12 CCD26844.1 - 0.0053 16.5 17.2 0.0053 16.5 17.2 2.6 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 CCD26844.1 - 0.087 10.9 30.2 0.093 10.8 20.2 2.5 2 0 0 2 2 2 0 DNA polymerase phi BUD22 PF09073.10 CCD26844.1 - 0.45 9.8 28.2 0.24 10.7 25.2 2.0 2 0 0 2 2 2 0 BUD22 MFS_1 PF07690.16 CCD26845.1 - 6.1e-32 110.9 32.5 6.1e-32 110.9 32.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Radial_spoke PF04712.12 CCD26845.1 - 0.0048 15.9 1.6 0.0087 15.1 1.6 1.3 1 0 0 1 1 1 1 Radial spokehead-like protein Myc_N PF01056.18 CCD26845.1 - 0.37 10.7 5.6 0.56 10.1 5.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Integrase_H2C2 PF17921.1 CCD26846.1 - 4.5e-08 33.1 0.6 1e-07 31.9 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CCD26846.1 - 2.3e-07 31.0 0.0 3.9e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 CCD26846.1 - 0.023 14.9 0.4 0.06 13.6 0.4 1.8 1 0 0 1 1 1 0 H2C2 zinc finger SKN1 PF03935.15 CCD26847.1 - 9.7e-253 839.0 5.1 1.3e-252 838.7 5.1 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Vps62 PF06101.11 CCD26849.1 - 0.00046 18.6 1.3 0.00046 18.6 1.3 1.5 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 MCM PF00493.23 CCD26850.1 - 6.7e-104 345.9 0.4 1e-103 345.2 0.4 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCD26850.1 - 3.6e-40 136.7 0.1 1.6e-39 134.6 0.1 2.1 3 0 0 3 3 3 1 MCM OB domain MCM6_C PF18263.1 CCD26850.1 - 3.1e-32 111.0 6.4 3.1e-32 111.0 6.4 2.0 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 CCD26850.1 - 7.5e-27 93.6 1.1 1.8e-26 92.4 1.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CCD26850.1 - 3.2e-25 88.7 0.4 3.2e-25 88.7 0.4 2.5 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 CCD26850.1 - 2.5e-07 30.3 0.0 1.2e-06 28.1 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CCD26850.1 - 0.0044 16.7 0.0 0.0093 15.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 CCD26850.1 - 0.0058 16.6 0.0 0.033 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CCD26850.1 - 0.0092 15.8 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GIDA_assoc PF13932.6 CCD26850.1 - 0.081 13.1 2.3 0.064 13.4 0.3 1.9 2 0 0 2 2 1 0 GidA associated domain RRN3 PF05327.11 CCD26850.1 - 0.47 8.9 12.4 0.93 8.0 12.4 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PTPRCAP PF15713.5 CCD26850.1 - 3.5 7.9 10.5 20 5.5 0.1 2.8 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Aminotran_1_2 PF00155.21 CCD26851.1 - 6.2e-23 81.5 0.0 8.3e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CCD26851.1 - 4.8e-05 22.8 0.0 7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 CCD26851.1 - 0.00046 19.3 0.0 0.00078 18.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CCD26851.1 - 0.0087 15.4 0.0 0.03 13.6 0.0 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Acetyltransf_10 PF13673.7 CCD26852.1 - 0.16 11.9 0.1 0.49 10.3 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Peptidase_S10 PF00450.22 CCD26853.1 - 3.1e-95 320.1 20.0 8.1e-95 318.7 20.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase Presenilin PF01080.17 CCD26853.1 - 0.0017 17.2 10.7 0.087 11.6 0.8 2.4 2 0 0 2 2 2 2 Presenilin Connexin PF00029.19 CCD26853.1 - 0.0068 16.2 4.4 0.15 11.8 0.6 2.4 2 0 0 2 2 2 1 Connexin DUF913 PF06025.12 CCD26853.1 - 0.013 14.6 10.6 0.26 10.2 1.2 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) KNOX1 PF03790.13 CCD26853.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 KNOX1 domain MID_MedPIWI PF18296.1 CCD26853.1 - 0.015 15.1 6.2 0.32 10.8 0.8 2.5 2 0 0 2 2 2 0 MID domain of medPIWI RPOL_N PF14700.6 CCD26853.1 - 0.015 14.7 3.3 2.1 7.7 0.1 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal Rxt3 PF08642.10 CCD26853.1 - 0.017 15.9 1.2 0.017 15.9 1.2 3.3 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 Ureide_permease PF07168.11 CCD26853.1 - 0.019 13.7 7.9 0.054 12.2 2.0 2.3 2 0 0 2 2 2 0 Ureide permease Ctr PF04145.15 CCD26853.1 - 0.036 14.7 3.7 0.18 12.4 0.8 2.6 2 0 0 2 2 2 0 Ctr copper transporter family DUF2370 PF10176.9 CCD26853.1 - 0.087 12.5 9.8 0.28 10.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Mpp10 PF04006.12 CCD26853.1 - 0.14 10.5 43.8 0.33 9.4 2.9 2.3 2 0 0 2 2 2 0 Mpp10 protein Neur_chan_memb PF02932.16 CCD26853.1 - 0.21 11.6 2.1 3.9 7.5 0.3 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region NPR3 PF03666.13 CCD26853.1 - 0.24 10.1 19.6 0.63 8.8 4.8 2.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SID-1_RNA_chan PF13965.6 CCD26853.1 - 0.37 9.2 11.2 1.1 7.6 0.1 2.9 2 1 1 3 3 3 0 dsRNA-gated channel SID-1 FAM60A PF15396.6 CCD26853.1 - 0.43 10.6 14.5 2.1 8.3 2.2 2.7 2 0 0 2 2 2 0 Protein Family FAM60A EOS1 PF12326.8 CCD26853.1 - 0.64 9.9 2.5 5.1 7.0 0.5 2.3 2 0 0 2 2 2 0 N-glycosylation protein SDA1 PF05285.12 CCD26853.1 - 0.91 8.9 45.8 1 8.8 0.4 3.2 3 0 0 3 3 3 0 SDA1 Eapp_C PF10238.9 CCD26853.1 - 1.2 9.2 15.3 4.2 7.4 5.2 2.7 2 0 0 2 2 2 0 E2F-associated phosphoprotein CSG2 PF16965.5 CCD26853.1 - 1.3 7.9 9.8 7.1 5.5 4.6 2.2 2 0 0 2 2 2 0 Ceramide synthase regulator AAA_11 PF13086.6 CCD26853.1 - 1.7 8.4 9.7 2.2 8.0 2.5 2.3 2 0 0 2 2 2 0 AAA domain DDHD PF02862.17 CCD26853.1 - 2.6 8.1 16.3 0.13 12.4 0.2 2.7 2 1 0 2 2 2 0 DDHD domain DUF5308 PF17233.2 CCD26853.1 - 3.5 7.8 8.7 5.3 7.2 0.4 2.6 3 0 0 3 3 2 0 Family of unknown function (DUF5308) EIIBC-GUT_N PF03612.14 CCD26853.1 - 3.5 7.3 12.2 12 5.6 5.4 2.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Serinc PF03348.15 CCD26853.1 - 4.5 6.1 11.2 4.2 6.2 0.7 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) Gti1_Pac2 PF09729.9 CCD26853.1 - 5.9 6.9 18.7 0.81 9.8 3.1 2.8 4 0 0 4 4 2 0 Gti1/Pac2 family FAM91_C PF14648.6 CCD26853.1 - 6.1 5.6 9.5 1.1 8.0 3.4 2.1 2 0 0 2 2 2 0 FAM91 C-terminus OATP PF03137.20 CCD26853.1 - 7.2 4.8 5.8 9.1 4.4 2.3 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Band_3_cyto PF07565.13 CCD26853.1 - 7.6 6.2 7.6 7.7 6.2 3.2 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF719 PF05334.13 CCD26853.1 - 8.4 6.5 13.8 3.3 7.9 2.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF719) BUD22 PF09073.10 CCD26853.1 - 9.1 5.5 46.9 9.7 5.4 1.5 2.7 2 1 0 2 2 2 0 BUD22 Retrotrans_gag PF03732.17 CCD26854.1 - 0.0014 18.8 0.0 0.0027 18.0 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Retrotran_gag_2 PF14223.6 CCD26854.1 - 0.098 12.3 0.0 0.2 11.3 0.0 1.5 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type CDP-OH_P_transf PF01066.21 CCD26855.1 - 7e-11 42.7 0.3 7e-11 42.7 0.3 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NST1 PF13945.6 CCD26855.1 - 0.1 12.7 9.0 0.15 12.2 9.0 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF1635 PF07795.11 CCD26855.1 - 0.48 10.3 5.3 0.69 9.7 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Tim54 PF11711.8 CCD26855.1 - 1.2 7.9 3.9 1.4 7.6 3.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 ACOX PF01756.19 CCD26856.1 - 1.6e-41 141.9 0.0 2.8e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 CCD26856.1 - 5.7e-21 74.5 0.0 1e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 CCD26856.1 - 3.8e-12 46.9 0.1 1.1e-11 45.3 0.1 1.8 1 1 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 CCD26856.1 - 0.011 16.0 0.0 0.028 14.6 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain AMPK1_CBM PF16561.5 CCD26857.1 - 1e-28 99.4 0.0 2.9e-28 97.9 0.0 1.8 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 CCD26857.1 - 4.2e-26 91.0 0.0 4.2e-26 91.0 0.0 2.3 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain zf-H2C2_2 PF13465.6 CCD26858.1 - 2.2e-07 31.0 20.1 0.00012 22.4 7.9 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCD26858.1 - 3.1e-06 27.5 15.6 0.0069 17.1 2.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CCD26858.1 - 7.7e-06 26.1 27.7 3e-05 24.2 4.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 CCD26858.1 - 0.0077 16.8 0.2 0.019 15.6 0.2 1.6 1 0 0 1 1 1 1 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 CCD26858.1 - 0.017 15.1 12.0 0.49 10.5 0.2 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CCD26858.1 - 1.7 8.5 14.7 0.45 10.3 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 CCD26858.1 - 3 8.4 7.5 21 5.6 0.4 2.9 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 CCD26858.1 - 3.7 7.9 14.6 0.33 11.3 0.7 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CCD26858.1 - 7.8 6.5 7.4 4.5 7.3 0.6 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Ras PF00071.22 CCD26859.1 - 2.7e-60 202.6 0.4 3.2e-60 202.4 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCD26859.1 - 1.2e-34 119.1 0.2 1.9e-34 118.5 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD26859.1 - 2.7e-13 49.8 0.0 3.5e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCD26859.1 - 5.5e-07 29.7 0.1 9.2e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCD26859.1 - 0.00012 21.7 0.1 0.0008 19.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CCD26859.1 - 0.0016 17.8 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CCD26859.1 - 0.0017 18.3 0.1 0.01 15.7 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase KAP_NTPase PF07693.14 CCD26859.1 - 0.0064 15.8 0.1 0.014 14.7 0.1 1.5 1 1 0 1 1 1 1 KAP family P-loop domain PduV-EutP PF10662.9 CCD26859.1 - 0.0076 16.0 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CCD26859.1 - 0.011 16.2 0.0 0.018 15.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 CCD26859.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CCD26859.1 - 0.017 15.4 0.1 0.052 13.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CCD26859.1 - 0.022 14.5 0.1 0.06 13.1 0.1 1.8 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 CCD26859.1 - 0.024 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Lipase_GDSL PF00657.22 CCD26859.1 - 0.028 14.4 0.6 0.088 12.8 0.1 2.0 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase ABC_tran PF00005.27 CCD26859.1 - 0.036 14.6 0.5 0.058 13.9 0.3 1.5 1 1 0 1 1 1 0 ABC transporter Septin PF00735.18 CCD26859.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Septin DUF1128 PF06569.11 CCD26859.1 - 0.044 13.8 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) AAA_7 PF12775.7 CCD26859.1 - 0.054 13.0 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MgpC PF05220.12 CCD26859.1 - 0.065 12.5 0.8 1.3 8.3 0.1 2.1 1 1 1 2 2 2 0 MgpC protein precursor ATP_bind_3 PF01171.20 CCD26860.1 - 9.2e-20 71.2 0.0 1.5e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 CCD26860.1 - 6.9e-18 63.8 2.3 6.9e-18 63.8 2.3 3.3 3 0 0 3 3 3 1 Zinc-ribbon tRNA_Me_trans PF03054.16 CCD26860.1 - 0.0021 16.9 0.0 0.0036 16.1 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.19 CCD26860.1 - 0.033 14.2 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family DUF2616 PF11077.8 CCD26860.1 - 0.081 12.6 3.2 0.23 11.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) CTU2 PF10288.9 CCD26860.1 - 0.16 12.3 0.1 0.16 12.3 0.1 2.7 3 1 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 PX PF00787.24 CCD26861.1 - 7.2e-09 35.6 0.7 1.8e-08 34.3 0.7 1.8 1 0 0 1 1 1 1 PX domain SNARE PF05739.19 CCD26861.1 - 0.19 11.7 0.8 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 SNARE domain Snapin_Pallidin PF14712.6 CCD26861.1 - 0.84 10.1 11.2 5.8 7.4 0.1 2.9 2 0 0 2 2 2 0 Snapin/Pallidin Med9 PF07544.13 CCD26861.1 - 0.97 9.6 6.6 13 6.0 0.0 3.3 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.12 CCD26861.1 - 8.4 6.9 8.4 2.9 8.4 2.2 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ANAPC4_WD40 PF12894.7 CCD26862.1 - 5.1e-10 39.5 0.0 6.6e-05 23.1 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCD26862.1 - 6.7e-10 39.4 16.0 3.1e-05 24.7 0.4 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat BBS2_Mid PF14783.6 CCD26862.1 - 0.06 13.4 0.0 0.32 11.1 0.0 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Cyclin_N PF00134.23 CCD26863.1 - 0.00017 21.3 0.1 0.00079 19.2 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Kinesin PF00225.23 CCD26864.1 - 1.3e-113 379.3 5.3 1.3e-113 379.3 5.3 2.6 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CCD26864.1 - 3.7e-27 95.1 0.4 3.7e-27 95.1 0.4 2.9 3 0 0 3 3 3 1 Microtubule binding IMD PF08397.11 CCD26864.1 - 0.0078 15.6 4.2 0.02 14.3 4.2 1.7 1 0 0 1 1 1 1 IRSp53/MIM homology domain BolA PF01722.18 CCD26866.1 - 4e-17 62.2 0.0 4.5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein FAD_binding_3 PF01494.19 CCD26867.1 - 1.4e-17 64.0 0.1 2.4e-09 36.9 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Lycopene_cycl PF05834.12 CCD26867.1 - 0.00048 19.3 0.0 0.0022 17.1 0.0 2.0 3 0 0 3 3 3 1 Lycopene cyclase protein SE PF08491.10 CCD26867.1 - 0.0016 17.6 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 CCD26867.1 - 0.0051 16.1 0.0 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCD26867.1 - 0.03 13.5 0.1 0.06 12.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 CCD26867.1 - 0.085 11.9 0.3 0.13 11.3 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 CCD26867.1 - 0.12 12.6 0.1 0.3 11.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CCD26867.1 - 0.15 11.3 0.0 0.41 9.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NIF3 PF01784.18 CCD26868.1 - 1.3e-66 224.8 0.1 1.6e-66 224.5 0.1 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) ABC_tran PF00005.27 CCD26870.1 - 9.3e-50 168.7 1.0 9.4e-25 87.7 0.0 2.9 4 0 0 4 4 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CCD26870.1 - 7.9e-21 73.9 4.7 7.9e-21 73.9 4.7 3.3 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 CCD26870.1 - 1.3e-20 74.5 4.2 3.2e-07 30.5 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCD26870.1 - 2e-08 34.0 6.2 0.089 12.2 0.1 4.7 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCD26870.1 - 6.6e-08 32.2 0.0 0.0034 17.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCD26870.1 - 3.6e-07 30.2 0.4 0.0016 18.3 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 CCD26870.1 - 5.4e-07 30.0 0.0 0.046 14.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 CCD26870.1 - 1.4e-06 28.9 9.7 0.046 14.2 0.0 4.2 4 0 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.23 CCD26870.1 - 3.4e-06 27.1 0.1 0.012 15.7 0.0 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 CCD26870.1 - 5e-06 26.5 5.3 0.052 13.3 0.0 3.9 3 1 1 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 CCD26870.1 - 6e-06 26.8 0.0 0.019 15.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CCD26870.1 - 1.7e-05 25.1 0.0 0.18 12.2 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 CCD26870.1 - 2.6e-05 24.5 0.0 0.11 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CCD26870.1 - 6.7e-05 23.3 0.1 0.31 11.5 0.0 3.2 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CCD26870.1 - 6.9e-05 22.8 1.0 0.32 10.9 0.0 3.0 3 0 0 3 3 2 2 NACHT domain AAA_16 PF13191.6 CCD26870.1 - 9.1e-05 22.9 0.2 0.25 11.7 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain AAA_24 PF13479.6 CCD26870.1 - 0.00017 21.4 0.1 0.26 11.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 CCD26870.1 - 0.00024 21.1 0.0 0.52 10.2 0.0 2.7 3 0 0 3 3 2 2 Rad17 P-loop domain AAA_33 PF13671.6 CCD26870.1 - 0.00031 20.9 1.4 0.4 10.8 0.0 3.3 4 0 0 4 4 2 1 AAA domain AAA_14 PF13173.6 CCD26870.1 - 0.00037 20.5 0.0 1.3 9.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain MCM PF00493.23 CCD26870.1 - 0.002 17.3 0.0 2.1 7.4 0.0 2.4 2 0 0 2 2 2 2 MCM P-loop domain Roc PF08477.13 CCD26870.1 - 0.0026 17.9 0.0 1.4 9.2 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 CCD26870.1 - 0.0056 16.7 0.0 3.5 7.6 0.1 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CCD26870.1 - 0.0058 16.2 0.0 1.5 8.4 0.0 3.5 4 0 0 4 4 3 1 AAA domain VirE PF05272.11 CCD26870.1 - 0.0087 15.8 0.0 1.3 8.8 0.0 2.9 3 0 0 3 3 3 1 Virulence-associated protein E AAA_7 PF12775.7 CCD26870.1 - 0.0089 15.6 0.1 1.3 8.5 0.0 3.0 3 1 1 4 4 4 1 P-loop containing dynein motor region NB-ARC PF00931.22 CCD26870.1 - 0.0097 15.1 0.1 1.1 8.4 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain G-alpha PF00503.20 CCD26870.1 - 0.0098 15.1 0.4 1.1 8.4 0.1 2.8 2 2 1 3 3 3 1 G-protein alpha subunit MeaB PF03308.16 CCD26870.1 - 0.012 14.6 0.1 2.6 7.0 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 CCD26870.1 - 0.018 15.0 0.2 3.6 7.6 0.0 2.8 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CCD26870.1 - 0.021 14.0 0.5 7.2 5.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CCD26870.1 - 0.026 14.2 0.0 0.69 9.6 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein PduV-EutP PF10662.9 CCD26870.1 - 0.034 13.9 0.1 10 5.8 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation dNK PF01712.19 CCD26870.1 - 0.066 13.1 0.0 11 5.8 0.0 2.7 2 0 0 2 2 2 0 Deoxynucleoside kinase Dynamin_N PF00350.23 CCD26870.1 - 0.068 13.2 7.3 3.5 7.7 0.0 4.1 3 1 0 4 4 4 0 Dynamin family NTPase_1 PF03266.15 CCD26870.1 - 0.072 13.0 0.1 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.17 CCD26870.1 - 0.075 12.8 0.2 22 4.7 0.1 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 CCD26870.1 - 0.085 12.4 0.0 3.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF87 PF01935.17 CCD26870.1 - 0.49 10.5 7.3 14 5.7 0.0 3.8 4 1 1 5 5 4 0 Helicase HerA, central domain AAA_17 PF13207.6 CCD26870.1 - 0.96 9.9 4.0 38 4.7 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA_27 PF13514.6 CCD26870.1 - 1.1 8.9 8.7 3.3 7.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain DUF2813 PF11398.8 CCD26870.1 - 1.8 7.8 5.7 4.3 6.5 0.0 3.2 5 0 0 5 5 3 0 Protein of unknown function (DUF2813) RtcB PF01139.17 CCD26870.1 - 7.1 5.7 7.3 1 8.4 2.7 1.7 2 0 0 2 2 2 0 tRNA-splicing ligase RtcB ATPase_2 PF01637.18 CCD26870.1 - 9.8 6.0 7.0 23 4.8 0.0 3.0 4 0 0 4 4 2 0 ATPase domain predominantly from Archaea zf-HIT PF04438.16 CCD26871.1 - 0.0036 17.2 12.5 0.0059 16.5 12.5 1.3 1 0 0 1 1 1 1 HIT zinc finger DUF1642 PF07852.11 CCD26871.1 - 2 9.0 4.9 0.36 11.4 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1642) SRP1_TIP1 PF00660.17 CCD26872.1 - 5.2e-29 100.2 0.1 6.6e-29 99.9 0.1 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family YlzJ PF14035.6 CCD26872.1 - 0.074 13.3 0.0 0.6 10.4 0.0 2.0 2 0 0 2 2 2 0 YlzJ-like protein SelP_C PF04593.14 CCD26874.1 - 0.12 12.4 0.5 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 Selenoprotein P, C terminal region Hydrolase PF00702.26 CCD26875.1 - 0.00017 22.0 0.0 0.041 14.2 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Asparaginase PF00710.20 CCD26875.1 - 0.21 11.1 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Asparaginase, N-terminal EamA PF00892.20 CCD26876.1 - 1e-06 28.9 32.5 7e-05 23.0 10.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family Multi_Drug_Res PF00893.19 CCD26876.1 - 7.9 7.2 11.6 3.7 8.3 5.0 2.6 2 0 0 2 2 2 0 Small Multidrug Resistance protein COX4 PF02936.14 CCD26877.1 - 8.4e-09 35.6 0.1 1e-08 35.3 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3261 PF11659.8 CCD26877.1 - 0.044 13.6 0.0 0.066 13.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3261) HTH_1 PF00126.27 CCD26877.1 - 0.1 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Ost5 PF05251.12 CCD26878.1 - 7e-15 55.1 8.2 7.9e-15 54.9 8.2 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 SPRY PF00622.28 CCD26879.1 - 1.5e-25 89.6 0.0 7.8e-25 87.3 0.0 2.3 2 1 0 2 2 2 1 SPRY domain CLTH PF10607.9 CCD26879.1 - 1.1e-10 41.6 1.1 2.6e-10 40.4 1.1 1.7 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CCD26879.1 - 6e-05 22.9 0.0 0.0002 21.2 0.0 2.0 1 0 0 1 1 1 1 LisH JUPITER PF17054.5 CCD26880.1 - 0.0064 16.0 2.3 0.0095 15.4 2.3 1.3 1 0 0 1 1 1 1 Microtubule-Associated protein Jupiter SAPS PF04499.15 CCD26881.1 - 1.9e-159 531.6 14.6 1.9e-159 531.6 14.6 2.3 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein DUF3446 PF11928.8 CCD26881.1 - 0.059 13.7 2.6 0.14 12.5 0.8 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain CDC45 PF02724.14 CCD26881.1 - 1.4 7.1 11.0 3.4 5.9 11.0 1.5 1 0 0 1 1 1 0 CDC45-like protein DUF5644 PF18712.1 CCD26881.1 - 4.5 7.3 10.1 0.23 11.5 0.3 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5644) CPSF100_C PF13299.6 CCD26881.1 - 6.2 7.0 9.3 17 5.5 0.3 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Acyl_transf_3 PF01757.22 CCD26882.1 - 0.0034 16.5 1.1 0.0045 16.1 1.1 1.1 1 0 0 1 1 1 1 Acyltransferase family DUF1077 PF06417.12 CCD26883.1 - 9.7e-41 138.5 4.3 1.3e-40 138.1 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) THUMP PF02926.17 CCD26884.1 - 1.1e-24 87.1 0.8 1.9e-24 86.4 0.1 1.7 2 0 0 2 2 2 1 THUMP domain Sec15 PF04091.12 CCD26885.1 - 1.6e-105 353.0 11.3 1.6e-105 353.0 11.3 2.3 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Latarcin PF10279.9 CCD26885.1 - 0.12 12.8 0.0 0.47 10.9 0.0 2.0 1 1 0 1 1 1 0 Latarcin precursor GARS_A PF01071.19 CCD26886.1 - 4.2e-81 271.4 0.0 6.6e-81 270.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 CCD26886.1 - 2.7e-34 117.8 0.0 8.7e-34 116.2 0.0 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 CCD26886.1 - 3.1e-30 105.4 0.0 7.9e-30 104.0 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 CCD26886.1 - 3.3e-28 97.8 0.7 7e-28 96.7 0.3 1.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 CCD26886.1 - 2.8e-17 63.2 1.3 5.5e-16 59.0 2.0 2.4 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 CCD26886.1 - 2.1e-05 24.6 0.3 5.7e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain GIDA PF01134.22 CCD26887.1 - 5.4e-155 516.3 0.0 7.2e-155 515.9 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 CCD26887.1 - 4.4e-71 239.4 0.1 7e-71 238.7 0.1 1.3 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 CCD26887.1 - 9e-07 28.4 2.3 2.5e-05 23.6 1.7 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CCD26887.1 - 0.00078 18.9 0.6 0.0013 18.2 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CCD26887.1 - 0.0023 18.5 0.3 0.0096 16.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCD26887.1 - 0.011 15.0 0.0 0.14 11.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CCD26887.1 - 0.021 13.9 1.1 0.021 13.9 1.1 1.9 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.12 CCD26887.1 - 0.08 12.0 0.3 0.21 10.6 0.3 1.7 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 CCD26887.1 - 0.29 9.8 3.6 1.9 7.1 0.4 2.6 3 0 0 3 3 3 0 HI0933-like protein CBFB_NFYA PF02045.15 CCD26888.1 - 8.8e-27 93.5 7.3 8.8e-27 93.5 7.3 2.8 3 1 0 3 3 3 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Cse1 PF08506.10 CCD26889.1 - 2.8e-168 559.5 13.0 6e-168 558.4 13.0 1.6 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 CCD26889.1 - 1.9e-104 349.6 11.2 1.9e-104 349.6 11.2 2.1 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 CCD26889.1 - 3.8e-16 58.8 2.7 1.2e-15 57.2 0.0 3.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CCD26889.1 - 0.00095 19.2 0.1 0.00095 19.2 0.1 3.7 5 0 0 5 5 5 1 Exportin 1-like protein ANAPC10 PF03256.16 CCD26890.1 - 5e-33 114.3 0.0 6.6e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 CCD26890.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 F5/8 type C domain PITH PF06201.13 CCD26890.1 - 0.1 12.8 0.0 0.32 11.2 0.0 1.7 1 1 1 2 2 2 0 PITH domain A_deamin PF02137.18 CCD26891.1 - 4.7e-27 95.3 0.7 6.4e-27 94.9 0.7 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Plus-3 PF03126.18 CCD26892.1 - 1.6e-26 93.0 0.0 9.9e-26 90.4 0.0 2.3 2 0 0 2 2 2 1 Plus-3 domain tRNA-synt_1c PF00749.21 CCD26893.1 - 2.9e-121 404.2 0.1 3.9e-121 403.8 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CCD26893.1 - 7.1e-38 130.2 0.5 1.8e-37 128.9 0.5 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GluRS_N PF18466.1 CCD26893.1 - 1.2e-10 41.7 0.8 3.7e-10 40.1 0.8 2.0 1 0 0 1 1 1 1 Glutamate--tRNA ligase N-terminal domain GST_C PF00043.25 CCD26893.1 - 0.036 14.3 0.0 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCD26893.1 - 0.036 14.1 0.0 0.099 12.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PocR PF10114.9 CCD26893.1 - 0.13 12.0 0.0 21 4.8 0.0 3.1 3 0 0 3 3 3 0 Sensory domain found in PocR RAI1 PF08652.11 CCD26894.1 - 4.5e-27 94.0 0.1 8.5e-27 93.1 0.1 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease PDEase_II PF02112.15 CCD26895.1 - 2.3e-65 220.9 0.2 3.1e-65 220.5 0.2 1.1 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II DUF2420 PF10336.9 CCD26897.1 - 4.5e-37 126.4 1.3 7.3e-37 125.7 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) PRO8NT PF08082.11 CCD26897.1 - 0.76 9.7 7.3 4.6 7.2 2.6 2.3 2 0 0 2 2 2 0 PRO8NT (NUC069), PrP8 N-terminal domain Sec63 PF02889.16 CCD26898.1 - 7.8e-30 103.9 1.5 1.4e-29 103.1 1.5 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 CCD26898.1 - 5.4e-25 88.2 0.0 1.4e-24 86.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CCD26898.1 - 1.2e-13 51.4 1.2 2.7e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCD26898.1 - 1.6e-10 41.3 3.0 1.6e-09 38.1 0.0 3.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CCD26898.1 - 0.011 16.1 0.1 0.055 13.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 CCD26898.1 - 0.022 13.9 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 CCD26898.1 - 0.032 14.0 0.0 0.087 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CCD26898.1 - 0.11 12.8 0.0 0.45 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ppx-GppA PF02541.16 CCD26899.1 - 8.6e-69 232.1 0.0 1.2e-68 231.7 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Hexokinase_2 PF03727.16 CCD26900.1 - 2.5e-79 266.1 0.0 3.5e-79 265.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CCD26900.1 - 6.6e-71 238.3 0.0 9.2e-71 237.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.21 CCD26900.1 - 0.021 14.4 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain YcgL PF05166.13 CCD26900.1 - 0.069 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 YcgL domain zf-C2H2 PF00096.26 CCD26901.1 - 1.3e-10 41.2 30.8 5.6e-05 23.4 0.6 5.6 5 1 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD26901.1 - 1.4e-07 31.7 26.9 0.00013 22.5 0.2 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCD26901.1 - 6e-07 29.6 7.5 0.00047 20.5 1.6 5.0 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CCD26901.1 - 0.00019 21.6 0.2 0.00019 21.6 0.2 3.8 4 1 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 CCD26901.1 - 0.0019 18.6 8.5 0.023 15.1 5.2 2.8 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 CCD26901.1 - 0.0058 17.0 8.9 0.033 14.6 0.2 4.1 4 0 0 4 4 4 1 Zinc-finger of C2H2 type T3RM_EcoP15I_C PF18273.1 CCD26901.1 - 0.068 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Type III R-M EcoP15I C-terminal domain zf-C2H2_aberr PF17017.5 CCD26901.1 - 0.22 11.6 13.1 9 6.4 0.8 4.5 1 1 3 4 4 4 0 Aberrant zinc-finger DNA_RNApol_7kD PF03604.13 CCD26901.1 - 0.43 10.3 4.1 7.6 6.3 0.2 2.7 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit FOXP-CC PF16159.5 CCD26901.1 - 1.4 9.6 15.9 12 6.6 0.0 5.0 3 1 2 5 5 5 0 FOXP coiled-coil domain PLA2_B PF01735.18 CCD26902.1 - 3.2e-188 626.1 3.9 6.7e-188 625.1 3.9 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 CCD26902.1 - 0.01 16.1 1.0 0.019 15.2 1.0 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Peptidase_C39_2 PF13529.6 CCD26902.1 - 0.064 13.8 4.3 0.085 13.4 1.2 2.3 2 0 0 2 2 2 0 Peptidase_C39 like family Peptidase_M16 PF00675.20 CCD26903.1 - 6.7e-27 94.3 0.0 1.1e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CCD26903.1 - 0.00028 21.0 0.1 0.0021 18.1 0.0 2.3 2 1 0 2 2 2 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.13 CCD26904.1 - 1.4e-64 218.3 10.6 6.9e-64 216.1 7.2 2.3 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 CCD26904.1 - 3.7e-19 68.6 7.6 4.4e-16 58.7 0.7 3.4 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 CCD26904.1 - 0.00049 19.9 2.1 0.21 11.4 0.1 2.7 2 0 0 2 2 2 2 TFIIE alpha subunit Rio2_N PF09202.11 CCD26904.1 - 0.11 12.7 1.5 1.5 9.1 0.1 2.8 2 0 0 2 2 2 0 Rio2, N-terminal TPR_22 PF18833.1 CCD26905.1 - 9.5e-42 141.0 0.7 3.1e-41 139.4 0.7 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCD26905.1 - 9.4e-24 83.7 1.5 1.2e-05 25.7 0.0 8.9 8 3 3 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 CCD26905.1 - 2.4e-22 77.7 2.2 0.12 13.2 0.0 13.0 10 3 5 15 15 12 5 Tetratricopeptide repeat TPR_2 PF07719.17 CCD26905.1 - 1.6e-21 74.6 12.2 0.0054 16.8 0.0 13.5 15 1 0 15 15 14 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCD26905.1 - 6.1e-21 73.8 0.8 9.7e-05 22.0 0.0 9.8 7 2 3 10 10 10 4 TPR repeat TPR_8 PF13181.6 CCD26905.1 - 1.3e-20 71.8 14.8 4.7e-05 23.3 0.0 11.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 CCD26905.1 - 2.8e-16 59.9 0.0 0.028 15.1 0.0 7.3 7 1 0 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 CCD26905.1 - 1.2e-15 56.5 15.1 0.0064 16.3 0.0 12.5 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCD26905.1 - 2.5e-13 49.4 0.4 0.052 14.0 0.0 9.2 11 0 0 11 11 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCD26905.1 - 6.7e-11 42.3 6.3 0.16 12.3 0.0 8.5 7 1 2 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD26905.1 - 9.6e-09 35.4 3.3 0.48 10.7 0.0 6.9 7 1 1 8 8 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CCD26905.1 - 1.6e-07 31.4 0.1 0.1 12.8 0.0 6.4 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCD26905.1 - 1.7e-06 27.7 2.7 3.1 8.0 0.0 8.3 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 CCD26905.1 - 0.00061 20.3 7.0 0.33 11.7 0.0 7.6 8 0 0 8 8 6 1 Tetratricopeptide repeat TAtT PF16811.5 CCD26905.1 - 0.00075 18.9 0.8 0.013 14.8 0.1 3.0 2 1 0 2 2 2 1 TRAP transporter T-component Alkyl_sulf_dimr PF14863.6 CCD26905.1 - 0.0011 19.4 0.4 1.8 9.0 0.0 4.2 3 1 0 3 3 3 1 Alkyl sulfatase dimerisation HrpB1_HrpK PF09613.10 CCD26905.1 - 0.0017 18.0 0.4 0.061 13.0 0.0 3.6 4 0 0 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 CCD26905.1 - 0.012 15.9 0.2 6.3 7.2 0.0 5.4 5 2 2 7 7 6 0 Tetratricopeptide repeat BTAD PF03704.17 CCD26905.1 - 0.05 14.0 0.0 21 5.6 0.0 3.6 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 CCD26905.1 - 0.088 12.7 5.1 36 4.4 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat EF-hand_6 PF13405.6 CCD26906.1 - 2.3e-08 33.3 6.8 5.8e-06 25.8 0.5 5.0 4 1 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 CCD26906.1 - 2.6e-08 34.2 5.8 3.3e-05 24.3 4.0 3.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CCD26906.1 - 2e-06 26.9 7.4 5.2e-06 25.6 0.7 4.2 5 0 0 5 5 5 1 EF hand DUF1456 PF07308.13 CCD26906.1 - 8.1e-05 22.9 2.0 0.37 11.2 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1456) EF-hand_5 PF13202.6 CCD26906.1 - 0.00032 20.0 1.1 0.00032 20.0 1.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_14 PF17959.1 CCD26906.1 - 0.0077 16.6 1.0 1.1 9.6 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain Na_Ca_ex_C PF16494.5 CCD26906.1 - 0.053 14.0 0.2 0.064 13.7 0.2 1.4 1 1 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain Lipoprotein_3 PF00938.17 CCD26906.1 - 0.083 13.1 1.5 2.8 8.2 0.1 3.2 2 2 1 3 3 3 0 Lipoprotein EF-hand_8 PF13833.6 CCD26906.1 - 0.18 11.7 4.6 0.53 10.2 0.2 3.0 2 1 1 3 3 3 0 EF-hand domain pair DUF4576 PF15144.6 CCD26906.1 - 0.37 10.7 2.5 0.26 11.2 0.4 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4576) RNA_pol_Rpb6 PF01192.22 CCD26907.1 - 3.3e-17 62.1 0.1 5.3e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.26 CCD26908.1 - 3.7e-27 93.2 78.8 0.00048 20.4 1.7 9.3 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD26908.1 - 7.8e-20 69.9 73.8 9.8e-05 22.9 2.9 9.4 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCD26908.1 - 4.1e-12 45.9 73.8 0.00024 21.4 0.2 10.0 10 0 0 10 10 10 7 Zinc-finger double domain zf-met PF12874.7 CCD26908.1 - 0.00026 21.3 43.2 0.00097 19.4 1.2 9.0 10 0 0 10 10 10 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCD26908.1 - 0.00095 19.4 60.5 0.044 14.1 3.3 9.1 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.12 CCD26908.1 - 0.04 13.9 12.3 2.9 7.9 0.1 4.2 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger MqsA_antitoxin PF15731.5 CCD26908.1 - 4.4 7.4 9.0 10 6.2 0.2 3.6 3 1 0 3 3 3 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA FOXP-CC PF16159.5 CCD26908.1 - 4.6 7.9 27.1 0.92 10.2 0.2 6.9 5 1 2 7 7 7 0 FOXP coiled-coil domain ATG13 PF10033.9 CCD26909.1 - 5e-63 213.0 1.3 5e-63 213.0 1.3 2.0 2 0 0 2 2 2 1 Autophagy-related protein 13 SUIM_assoc PF16619.5 CCD26909.1 - 0.051 13.6 16.6 0.071 13.2 1.1 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 hDGE_amylase PF14701.6 CCD26910.1 - 4.2e-175 583.1 0.2 6.5e-175 582.5 0.2 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 CCD26910.1 - 2e-130 435.2 0.0 3.3e-130 434.5 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 CCD26910.1 - 5.6e-78 262.1 0.0 1e-77 261.2 0.0 1.5 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 CCD26910.1 - 1.4e-24 86.1 0.1 3.7e-24 84.7 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 CCD26910.1 - 0.0033 17.0 0.2 0.017 14.7 0.1 2.0 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Gly_acyl_tr_C PF08444.10 CCD26910.1 - 0.1 12.8 0.0 1.5 9.1 0.0 2.8 3 0 0 3 3 3 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region DUF445 PF04286.12 CCD26910.1 - 0.12 12.2 0.1 3.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Med11 PF10280.9 CCD26911.1 - 1e-16 61.6 2.5 9.2e-16 58.6 2.5 1.9 1 1 0 1 1 1 1 Mediator complex protein SUKH-3 PF14433.6 CCD26911.1 - 0.032 14.7 0.0 0.038 14.5 0.0 1.1 1 0 0 1 1 1 0 SUKH-3 immunity protein DUF5082 PF16888.5 CCD26911.1 - 0.041 14.2 0.7 0.06 13.6 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Cupredoxin_1 PF13473.6 CCD26911.1 - 0.058 13.5 0.1 0.11 12.6 0.0 1.5 2 0 0 2 2 2 0 Cupredoxin-like domain Glycos_transf_2 PF00535.26 CCD26912.1 - 1.4e-31 109.6 0.0 1.7e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CCD26912.1 - 7.8e-07 29.2 0.0 1.1e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CCD26912.1 - 8.8e-05 22.1 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 CKAP2_C PF15297.6 CCD26913.1 - 0.009 15.1 0.3 0.015 14.5 0.3 1.2 1 0 0 1 1 1 1 Cytoskeleton-associated protein 2 C-terminus Ras PF00071.22 CCD26915.1 - 1.3e-53 180.9 0.0 7.6e-53 178.4 0.0 1.8 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CCD26915.1 - 5.9e-20 71.7 0.0 1.2e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCD26915.1 - 2.5e-05 23.8 0.0 4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Orf78 PF06024.12 CCD26915.1 - 0.0014 18.9 0.4 0.0028 17.9 0.4 1.5 1 0 0 1 1 1 1 Orf78 (ac78) ETRAMP PF09716.10 CCD26915.1 - 0.0046 17.0 0.9 0.0071 16.4 0.9 1.4 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) TMEM154 PF15102.6 CCD26915.1 - 0.015 15.2 0.1 0.034 14.1 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family Shisa PF13908.6 CCD26915.1 - 0.034 14.4 0.2 0.061 13.6 0.2 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Ribosomal_S14 PF00253.21 CCD26916.1 - 1.1e-20 73.1 0.4 6.7e-20 70.6 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e PAPS_reduct PF01507.19 CCD26917.1 - 9.3e-41 139.8 0.0 1.1e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ANAPC4_WD40 PF12894.7 CCD26918.1 - 0.0003 21.0 1.0 0.42 10.9 0.3 3.5 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CCD26918.1 - 0.016 15.7 0.0 6 7.5 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Putative_PNPOx PF01243.20 CCD26920.1 - 3.1e-15 56.1 0.0 8.6e-15 54.7 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 CCD26920.1 - 0.021 14.8 0.0 2.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase AAA PF00004.29 CCD26921.1 - 2.7e-44 150.8 0.0 6.2e-44 149.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CCD26921.1 - 1.6e-29 101.6 0.3 5.5e-29 100.0 0.2 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 CCD26921.1 - 1.4e-23 82.7 4.2 4.3e-23 81.2 4.2 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_16 PF13191.6 CCD26921.1 - 4.3e-06 27.2 0.3 6e-05 23.5 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CCD26921.1 - 8.4e-06 25.6 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 CCD26921.1 - 1.3e-05 24.9 0.0 5.2e-05 23.0 0.0 2.1 2 0 0 2 2 1 1 AAA+ lid domain AAA_22 PF13401.6 CCD26921.1 - 2.4e-05 24.6 0.9 0.011 16.0 0.0 2.7 2 1 1 3 3 2 1 AAA domain AAA_5 PF07728.14 CCD26921.1 - 3.6e-05 23.8 0.0 0.00014 21.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CCD26921.1 - 6.3e-05 22.8 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CCD26921.1 - 0.00017 21.9 0.4 0.0084 16.5 0.0 3.0 4 0 0 4 4 2 1 RNA helicase DUF815 PF05673.13 CCD26921.1 - 0.00017 20.8 0.0 0.00049 19.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 CCD26921.1 - 0.00019 21.6 0.1 0.00082 19.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 CCD26921.1 - 0.0002 21.4 0.0 0.0007 19.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CCD26921.1 - 0.00025 20.4 0.0 0.00049 19.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 CCD26921.1 - 0.00091 19.8 0.0 0.0021 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CCD26921.1 - 0.0022 18.2 0.1 0.0052 17.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 CCD26921.1 - 0.0031 17.2 0.0 0.0099 15.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain DUF3543 PF12063.8 CCD26921.1 - 0.0065 15.9 0.6 0.01 15.2 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) AAA_25 PF13481.6 CCD26921.1 - 0.019 14.5 0.2 0.41 10.2 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 CCD26921.1 - 0.024 15.0 0.0 0.024 15.0 0.0 2.1 3 0 0 3 3 1 0 AAA domain Torsin PF06309.11 CCD26921.1 - 0.025 14.7 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Torsin Mg_chelatase PF01078.21 CCD26921.1 - 0.034 13.5 0.0 0.075 12.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 CCD26921.1 - 0.043 13.2 0.1 5.6 6.2 0.0 2.4 1 1 1 2 2 2 0 KaiC AAA_7 PF12775.7 CCD26921.1 - 0.057 12.9 0.0 0.13 11.7 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CCD26921.1 - 0.061 13.2 0.0 0.72 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 CCD26921.1 - 0.067 12.6 0.1 0.16 11.4 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 CCD26921.1 - 0.086 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 CCD26921.1 - 0.087 12.5 0.0 0.3 10.8 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CCD26921.1 - 0.13 11.6 0.3 1.3 8.3 0.1 2.4 1 1 2 3 3 3 0 Zeta toxin Methyltransf_32 PF13679.6 CCD26921.1 - 0.26 11.3 0.7 7.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Use1 PF09753.9 CCD26921.1 - 0.35 10.6 7.8 0.14 11.9 5.3 1.5 2 0 0 2 2 1 0 Membrane fusion protein Use1 AAA_11 PF13086.6 CCD26921.1 - 0.38 10.5 3.5 3.9 7.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain NBP1 PF08537.10 CCD26922.1 - 3e-25 89.4 24.3 2.9e-24 86.1 24.3 2.2 1 1 0 1 1 1 1 Fungal Nap binding protein NBP1 EMP24_GP25L PF01105.24 CCD26922.1 - 0.11 12.4 0.8 0.23 11.4 0.8 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4172 PF13776.6 CCD26922.1 - 0.15 12.4 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) IZUMO PF15005.6 CCD26922.1 - 0.23 12.0 0.2 0.23 12.0 0.2 2.1 2 1 1 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated DNA_pol_E_B PF04042.16 CCD26923.1 - 2.3e-53 180.7 0.8 2.3e-53 180.7 0.8 1.8 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Fusion_gly_K PF01621.17 CCD26923.1 - 0.12 11.4 0.0 0.28 10.2 0.0 1.5 1 0 0 1 1 1 0 Cell fusion glycoprotein K Prenyltrans PF00432.21 CCD26924.1 - 1.4e-69 229.4 3.2 2.4e-14 52.7 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 CCD26924.1 - 9.9e-07 28.1 0.0 0.00011 21.4 0.0 2.3 1 1 1 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CCD26924.1 - 9.6e-05 21.6 0.0 0.76 8.8 0.0 4.2 1 1 4 5 5 5 3 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 CCD26924.1 - 0.034 13.2 0.6 0.49 9.4 0.0 2.7 2 1 2 4 4 4 0 A-macroglobulin TED domain DUF4576 PF15144.6 CCD26924.1 - 0.048 13.5 0.0 7.5 6.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4576) WD40 PF00400.32 CCD26925.1 - 1e-33 114.8 14.9 7.1e-09 36.2 0.2 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD26925.1 - 2.6e-17 62.9 0.1 4.9e-05 23.5 0.0 5.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCD26925.1 - 5.7e-05 23.1 0.0 0.17 11.7 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CCD26925.1 - 0.0032 16.8 0.0 0.071 12.4 0.0 2.9 2 1 0 2 2 2 1 WD40-like domain HDA2-3 PF11496.8 CCD26926.1 - 2.5e-89 299.3 0.4 2.5e-89 299.3 0.4 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF1515 PF07439.11 CCD26926.1 - 0.0025 17.8 3.1 0.13 12.3 0.9 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1515) DUF812 PF05667.11 CCD26926.1 - 0.0035 16.3 21.1 0.0052 15.7 21.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 CCD26926.1 - 0.037 14.1 14.3 0.031 14.4 11.2 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Bcr-Abl_Oligo PF09036.10 CCD26926.1 - 0.12 12.3 2.1 5.3 7.1 0.1 2.9 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF4806 PF16064.5 CCD26926.1 - 0.18 12.1 0.0 0.18 12.1 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4806) TMF_DNA_bd PF12329.8 CCD26926.1 - 0.31 11.1 18.2 0.72 9.9 4.4 3.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 CCD26926.1 - 0.53 9.6 12.2 0.028 13.8 7.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.8 CCD26926.1 - 0.65 10.1 18.2 1.9 8.6 7.8 3.0 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spectrin_like PF18373.1 CCD26926.1 - 1.4 9.0 5.7 14 5.8 0.2 3.2 3 0 0 3 3 2 0 Spectrin like domain Tho2 PF11262.8 CCD26926.1 - 2.1 7.4 14.8 0.68 9.1 2.2 2.5 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Snapin_Pallidin PF14712.6 CCD26926.1 - 2.3 8.7 13.9 0.8 10.2 4.8 3.2 2 1 0 2 2 2 0 Snapin/Pallidin TMF_TATA_bd PF12325.8 CCD26926.1 - 6.8 7.0 22.3 0.11 12.7 1.7 3.2 2 2 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ThiF PF00899.21 CCD26927.1 - 3.9e-25 88.6 0.0 5.5e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sec23_trunk PF04811.15 CCD26928.1 - 4e-69 232.9 0.0 5.4e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CCD26928.1 - 1e-29 103.1 0.0 2.1e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CCD26928.1 - 2e-25 88.6 0.1 3.9e-25 87.7 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CCD26928.1 - 1.6e-13 50.5 3.7 3.6e-13 49.3 3.7 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CCD26928.1 - 4.5e-11 42.5 0.0 8.8e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CCD26928.1 - 0.00078 18.8 0.3 0.002 17.5 0.3 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 CCD26928.1 - 0.037 13.3 0.7 0.1 11.9 0.7 1.8 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-MIZ PF02891.20 CCD26928.1 - 0.12 12.2 0.9 0.26 11.1 0.9 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger PIG-U PF06728.13 CCD26929.1 - 6.7e-104 348.0 46.2 8.4e-104 347.6 46.2 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF5509 PF17625.2 CCD26929.1 - 0.41 9.7 3.8 0.39 9.8 2.8 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5509) LSM PF01423.22 CCD26930.1 - 5.9e-18 64.3 0.1 7.4e-18 64.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain ORC4_C PF14629.6 CCD26933.1 - 9.5e-42 142.8 2.9 1.7e-41 142.0 2.9 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_22 PF13401.6 CCD26933.1 - 0.001 19.4 0.0 0.0029 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain EXS PF03124.14 CCD26933.1 - 0.075 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 EXS family SEA PF01390.20 CCD26933.1 - 0.14 12.3 2.8 12 6.0 0.3 2.9 2 0 0 2 2 2 0 SEA domain ParB PF08775.10 CCD26933.1 - 0.32 11.5 3.2 2.2 8.7 0.2 3.5 3 1 1 4 4 4 0 ParB family Pkinase PF00069.25 CCD26934.1 - 1.4e-74 250.8 0.0 2e-74 250.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD26934.1 - 2.1e-30 105.9 0.0 8.9e-21 74.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CCD26934.1 - 3.9e-08 32.7 0.0 7.2e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain eIF2_C PF09173.11 CCD26935.1 - 8.5e-35 118.9 0.4 2e-34 117.7 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CCD26935.1 - 3.4e-23 82.2 0.3 3e-22 79.1 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CCD26935.1 - 1.2e-11 44.8 1.3 2.8e-11 43.7 0.4 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCD26935.1 - 0.0025 17.9 0.0 0.0056 16.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCD26935.1 - 0.0054 16.6 0.1 0.082 12.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CCD26935.1 - 0.039 14.0 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 CCD26935.1 - 1.2 9.1 3.2 1.9 8.5 0.1 2.8 2 1 0 2 2 2 0 Dynamin family Zn_clus PF00172.18 CCD26936.1 - 2.8e-08 33.7 11.2 4.6e-08 33.0 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Carn_acyltransf PF00755.20 CCD26938.1 - 1.7e-115 386.9 1.3 2.3e-115 386.5 1.3 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DsbG_N PF18257.1 CCD26938.1 - 0.02 15.0 3.6 0.026 14.7 1.2 2.3 2 0 0 2 2 2 0 Disulfide isomerase DsbG N-terminal Sporozoite_P67 PF05642.11 CCD26938.1 - 0.02 13.0 4.9 0.043 11.9 4.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CmlA_N PF18456.1 CCD26938.1 - 0.023 14.0 1.3 3.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Diiron non-heme beta-hydroxylase N-terminal domain CDC45 PF02724.14 CCD26938.1 - 0.028 12.7 4.3 0.049 11.9 4.3 1.4 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C37 PF05416.12 CCD26938.1 - 0.037 12.6 0.1 0.054 12.0 0.1 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase FAM176 PF14851.6 CCD26938.1 - 6.3 6.5 7.0 16 5.1 7.0 1.7 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 CCD26938.1 - 9 5.5 8.9 15 4.8 8.9 1.3 1 0 0 1 1 1 0 NOA36 protein Phage_int_SAM_5 PF13102.6 CCD26938.1 - 9.7 6.6 10.1 0.6 10.5 3.6 2.4 3 0 0 3 3 3 0 Phage integrase SAM-like domain CMD PF02627.20 CCD26939.1 - 2.4e-05 24.3 0.0 0.00011 22.2 0.0 2.0 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family Yippee-Mis18 PF03226.14 CCD26940.1 - 4.4e-14 52.6 1.7 8.1e-14 51.7 1.7 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 CCD26940.1 - 0.021 15.0 1.8 0.021 15.0 1.8 2.0 3 0 0 3 3 3 0 C-terminal domain of RIG-I G-alpha PF00503.20 CCD26941.1 - 1e-102 343.9 16.8 1e-102 343.9 16.8 1.8 1 1 1 2 2 2 1 G-protein alpha subunit Arf PF00025.21 CCD26941.1 - 8.9e-17 61.1 0.7 1.2e-10 41.1 0.3 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCD26941.1 - 1.1e-06 28.2 1.5 0.00012 21.5 0.1 2.7 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region TFIIA PF03153.13 CCD26941.1 - 0.0017 18.5 26.2 0.0027 17.8 26.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 CCD26941.1 - 0.004 15.3 20.7 0.004 15.3 20.7 1.6 2 0 0 2 2 2 1 DNA polymerase phi CDC45 PF02724.14 CCD26941.1 - 0.0047 15.3 12.1 0.0047 15.3 12.1 2.1 2 0 0 2 2 2 1 CDC45-like protein GP67 PF17634.2 CCD26941.1 - 0.024 15.1 20.2 0.024 15.1 20.2 2.5 1 1 1 2 2 1 0 Gene product 67 AAA_29 PF13555.6 CCD26941.1 - 0.075 12.8 0.6 0.16 11.7 0.6 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CCD26941.1 - 0.083 12.2 0.3 0.24 10.7 0.1 1.8 1 1 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 CCD26941.1 - 0.2 11.9 6.5 2 8.6 0.2 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase CCSAP PF15748.5 CCD26941.1 - 5.9 7.0 22.8 6.4 6.9 2.0 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Afi1 PF07792.12 CCD26941.1 - 8.9 6.8 29.5 9 6.8 8.6 2.5 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Med17 PF10156.9 CCD26942.1 - 8.9e-179 595.0 27.8 1.5e-178 594.3 27.8 1.4 1 0 0 1 1 1 1 Subunit 17 of Mediator complex P5CR_dimer PF14748.6 CCD26943.1 - 5.8e-34 116.4 0.6 1e-33 115.7 0.6 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CCD26943.1 - 1.3e-10 41.7 0.5 3.8e-10 40.2 0.1 2.0 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AAA-ATPase_like PF09820.9 CCD26943.1 - 0.22 10.9 0.0 0.3 10.5 0.0 1.1 1 0 0 1 1 1 0 Predicted AAA-ATPase Ribosomal_S7 PF00177.21 CCD26944.1 - 1.2e-36 125.6 2.1 1.7e-36 125.1 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e EF-hand_4 PF12763.7 CCD26945.1 - 2.9e-31 107.5 3.2 5.1e-10 39.2 0.4 4.6 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CCD26945.1 - 3.7e-09 35.5 0.5 0.00059 19.2 0.0 4.4 3 0 0 3 3 3 2 EF hand UBA PF00627.31 CCD26945.1 - 4.1e-09 36.2 0.0 1.3e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.6 CCD26945.1 - 3.5e-08 33.8 0.2 0.18 12.3 0.0 5.4 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 CCD26945.1 - 2.9e-05 23.6 0.1 1 9.5 0.0 4.6 3 0 0 3 3 3 1 EF-hand domain UBA_4 PF14555.6 CCD26945.1 - 0.0018 18.1 2.0 0.0019 18.0 0.2 2.1 2 0 0 2 2 2 1 UBA-like domain HrpB7 PF09486.10 CCD26945.1 - 0.002 18.5 5.7 0.002 18.5 5.7 3.8 2 1 2 4 4 4 1 Bacterial type III secretion protein (HrpB7) DUF1296 PF06972.11 CCD26945.1 - 0.49 10.6 0.0 0.49 10.6 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1296) DUF3584 PF12128.8 CCD26945.1 - 3.3 5.1 63.2 0.0027 15.3 48.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) VanZ PF04892.12 CCD26947.1 - 1.6e-08 35.2 7.0 1.2e-07 32.5 7.0 2.1 1 1 0 1 1 1 1 VanZ like family Urate_ox_N PF06181.11 CCD26947.1 - 0.041 13.2 0.0 0.075 12.4 0.0 1.4 1 1 0 1 1 1 0 Urate oxidase N-terminal PPP4R2 PF09184.11 CCD26948.1 - 2.3e-59 201.4 41.8 2.3e-59 201.4 41.8 3.6 1 1 1 2 2 2 1 PPP4R2 Peptidase_M16_C PF05193.21 CCD26949.1 - 8.3e-26 91.1 0.0 1.4e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CCD26949.1 - 1.4e-24 86.8 0.2 2.8e-24 85.8 0.2 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Transp_cyt_pur PF02133.15 CCD26951.1 - 1.6e-156 521.5 41.8 1.9e-156 521.3 41.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Proteasome PF00227.26 CCD26952.1 - 2.4e-35 121.8 0.0 1.4e-34 119.2 0.0 1.8 1 1 0 1 1 1 1 Proteasome subunit ER_lumen_recept PF00810.18 CCD26953.1 - 1.4e-45 155.7 14.2 1.4e-45 155.7 14.2 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor CTP_synth_N PF06418.14 CCD26955.1 - 1.3e-125 418.1 0.3 1.8e-125 417.6 0.3 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CCD26955.1 - 1.3e-56 191.4 0.0 2.1e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CCD26955.1 - 0.012 15.3 0.1 0.17 11.6 0.1 2.5 1 1 0 1 1 1 0 Peptidase C26 SUKH-3 PF14433.6 CCD26955.1 - 0.046 14.2 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 SUKH-3 immunity protein CbiA PF01656.23 CCD26955.1 - 0.062 13.4 0.0 0.095 12.8 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Med15_fungi PF05397.12 CCD26955.1 - 0.088 13.1 0.1 0.24 11.7 0.1 1.7 1 0 0 1 1 1 0 Mediator complex subunit 15 TMEM192 PF14802.6 CCD26956.1 - 0.79 8.8 7.3 0.045 12.9 2.3 1.5 2 0 0 2 2 2 0 TMEM192 family Nup54 PF13874.6 CCD26956.1 - 1.8 8.6 18.8 0.19 11.8 7.7 2.3 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 SAC3_GANP PF03399.16 CCD26957.1 - 1.9e-17 63.6 11.5 1.1e-15 57.8 11.5 2.3 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CCD26957.1 - 1.6e-07 31.4 3.8 3.3e-07 30.4 2.7 2.0 1 1 1 2 2 2 1 CSN8/PSMD8/EIF3K family PX PF00787.24 CCD26958.1 - 3.1e-07 30.4 0.3 8.7e-07 28.9 0.3 1.8 1 0 0 1 1 1 1 PX domain LisH_2 PF16045.5 CCD26958.1 - 0.0026 16.8 1.5 0.098 11.7 0.0 2.5 2 0 0 2 2 2 2 LisH mCpol PF18182.1 CCD26958.1 - 0.029 14.7 0.8 0.088 13.1 0.3 2.0 2 0 0 2 2 2 0 minimal CRISPR polymerase domain DUF3885 PF13021.6 CCD26958.1 - 0.063 13.4 1.1 0.17 12.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) Ribosomal_L37ae PF01780.19 CCD26959.1 - 3.8e-40 135.9 9.1 4.2e-40 135.7 9.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 CCD26959.1 - 0.00089 19.3 3.7 0.0013 18.8 3.7 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Rep_fac-A_C PF08646.10 CCD26959.1 - 0.0078 16.0 0.3 0.0089 15.8 0.3 1.2 1 0 0 1 1 1 1 Replication factor-A C terminal domain CarbpepA_inh PF02977.15 CCD26959.1 - 0.028 14.2 1.3 0.028 14.2 1.3 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Zn_Tnp_IS1595 PF12760.7 CCD26959.1 - 0.042 13.8 2.8 0.074 13.0 2.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Elf1 PF05129.13 CCD26959.1 - 0.048 13.7 1.3 0.08 13.0 1.3 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DUF2175 PF09943.9 CCD26959.1 - 0.072 13.4 0.5 4.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-H2C2_2 PF13465.6 CCD26959.1 - 0.085 13.3 0.8 2.2 8.8 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain C1_2 PF03107.16 CCD26959.1 - 0.23 11.8 2.1 10 6.5 2.4 2.0 1 1 1 2 2 2 0 C1 domain YyzF PF14116.6 CCD26959.1 - 0.38 10.8 1.3 0.58 10.2 0.2 1.7 2 0 0 2 2 2 0 YyzF-like protein zf-C4_ClpX PF06689.13 CCD26959.1 - 2.2 8.2 5.3 6.9 6.6 5.3 2.0 1 1 0 1 1 1 0 ClpX C4-type zinc finger PH PF00169.29 CCD26960.1 - 0.0022 18.5 0.0 0.0073 16.8 0.0 2.0 1 0 0 1 1 1 1 PH domain M-factor PF03855.13 CCD26960.1 - 0.19 11.9 1.7 1 9.5 1.7 2.4 1 0 0 1 1 1 0 M-factor PUF PF00806.19 CCD26961.1 - 2.4e-24 83.6 9.8 0.00019 20.9 0.1 6.9 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 CCD26961.1 - 6.4e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-5_eIF-2B PF01873.17 CCD26962.1 - 1.5e-37 128.0 0.0 3.1e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 CCD26962.1 - 8.8e-21 73.8 2.1 1.1e-20 73.5 0.0 2.3 3 1 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon ACT PF01842.25 CCD26962.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 ACT domain TPR_2 PF07719.17 CCD26963.1 - 1.6e-06 27.8 0.1 1.6e-05 24.7 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCD26963.1 - 9.2e-05 22.4 0.5 0.0057 16.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCD26963.1 - 0.00072 19.3 0.0 0.0031 17.3 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 CCD26963.1 - 0.0045 17.5 0.8 5.6 7.8 0.0 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCD26963.1 - 0.005 17.1 0.1 0.13 12.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat KxDL PF10241.9 CCD26963.1 - 0.017 15.4 0.2 0.017 15.4 0.2 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein TPR_9 PF13371.6 CCD26963.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat PknG_TPR PF16918.5 CCD26963.1 - 0.11 11.1 0.0 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat Mem_trans PF03547.18 CCD26964.1 - 1.5e-23 82.9 0.0 2.8e-23 82.0 0.0 1.5 1 1 0 1 1 1 1 Membrane transport protein TcpE PF12648.7 CCD26964.1 - 0.19 12.3 0.1 0.19 12.3 0.1 3.8 3 1 1 4 4 4 0 TcpE family Aldo_ket_red PF00248.21 CCD26965.1 - 3.4e-63 213.6 0.0 3.8e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CNPase PF05881.12 CCD26965.1 - 0.0095 15.5 0.0 0.034 13.7 0.0 1.8 2 0 0 2 2 2 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) Stm1_N PF09598.10 CCD26966.1 - 6.8e-12 46.1 2.7 6.8e-12 46.1 2.7 3.7 2 2 1 3 3 3 1 Stm1 Stb3 PF10330.9 CCD26967.1 - 9.3e-31 105.7 0.2 3.6e-30 103.9 0.0 2.1 2 0 0 2 2 2 1 Putative Sin3 binding protein CDC37_N PF03234.14 CCD26968.1 - 1.1e-42 146.0 10.0 1.1e-42 146.0 10.0 3.4 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 CCD26968.1 - 9.5e-38 128.8 1.4 9.5e-38 128.8 1.4 2.9 3 0 0 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 CCD26968.1 - 7.5e-28 96.6 4.3 7.5e-28 96.6 4.3 2.8 3 0 0 3 3 3 1 Cdc37 C terminal domain CKAP2_C PF15297.6 CCD26969.1 - 0.057 12.5 0.1 0.088 11.9 0.1 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus TFIID_30kDa PF03540.13 CCD26971.1 - 8.1e-26 89.7 0.1 1.3e-25 89.1 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 CCD26971.1 - 0.1 12.6 0.0 0.29 11.2 0.0 1.7 2 0 0 2 2 2 0 Bromodomain associated Sec5 PF15469.6 CCD26972.1 - 9.9e-55 185.3 15.0 9.9e-55 185.3 15.0 3.3 3 0 0 3 3 3 1 Exocyst complex component Sec5 SUIM_assoc PF16619.5 CCD26972.1 - 0.0028 17.7 2.0 0.077 13.1 1.2 2.6 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Vps51 PF08700.11 CCD26972.1 - 0.0033 17.5 4.8 0.0033 17.5 4.8 3.7 3 1 1 4 4 4 1 Vps51/Vps67 COG2 PF06148.11 CCD26972.1 - 0.026 14.6 8.4 0.015 15.4 5.4 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 WD40 PF00400.32 CCD26973.1 - 0.00043 21.0 0.3 0.29 12.1 0.2 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat CPSF_A PF03178.15 CCD26973.1 - 0.049 12.9 0.4 0.85 8.9 0.0 2.5 2 1 1 3 3 3 0 CPSF A subunit region zf-C2H2_10 PF16588.5 CCD26974.1 - 0.074 12.8 3.4 0.13 12.0 3.4 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_4 PF14392.6 CCD26974.1 - 0.11 12.2 0.4 0.2 11.4 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Sec1 PF00995.23 CCD26975.1 - 2.7e-91 307.5 8.3 3.2e-91 307.3 8.3 1.0 1 0 0 1 1 1 1 Sec1 family DUF3113 PF11310.8 CCD26975.1 - 0.051 13.5 2.1 0.096 12.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) Cwf_Cwc_15 PF04889.12 CCD26976.1 - 1.8e-14 54.1 8.8 2e-08 34.3 1.3 2.1 2 1 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein SH3_1 PF00018.28 CCD26977.1 - 1.2e-12 47.2 2.4 1.3e-12 47.1 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CCD26977.1 - 4.3e-10 39.3 0.1 4.3e-10 39.3 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CCD26977.1 - 9.4e-06 25.2 0.0 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TPR_2 PF07719.17 CCD26978.1 - 1e-06 28.4 0.7 0.13 12.4 0.0 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCD26978.1 - 5.3e-05 23.6 3.3 0.093 13.3 0.5 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CCD26978.1 - 8.6e-05 22.1 0.8 0.57 9.9 0.1 3.6 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.6 CCD26978.1 - 0.00012 22.6 0.0 0.7 10.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CCD26978.1 - 0.00013 22.1 0.4 0.022 15.0 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CCD26978.1 - 0.00016 21.7 0.2 2 8.8 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_3 PF07720.12 CCD26978.1 - 0.00025 21.0 0.0 2 8.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CCD26978.1 - 0.0017 18.1 0.2 0.55 10.1 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCD26978.1 - 0.057 13.5 0.1 4 7.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 CCD26978.1 - 0.12 12.1 1.2 0.44 10.2 0.3 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_17 PF13431.6 CCD26978.1 - 0.13 12.7 0.0 4.7 7.8 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 CCD26978.1 - 0.15 11.2 0.1 0.39 9.9 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat AA_permease PF00324.21 CCD26979.1 - 2.4e-76 257.3 50.0 1.6e-75 254.6 50.0 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCD26979.1 - 3.8e-27 95.2 52.3 1.9e-26 92.9 52.3 1.8 1 1 0 1 1 1 1 Amino acid permease DUF2618 PF10940.8 CCD26979.1 - 0.024 14.4 0.1 0.08 12.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) VirB3 PF05101.13 CCD26979.1 - 0.59 10.4 0.0 0.59 10.4 0.0 4.0 4 0 0 4 4 4 0 Type IV secretory pathway, VirB3-like protein SAC3_GANP PF03399.16 CCD26980.1 - 7.4e-100 334.1 2.8 1.8e-99 332.8 1.1 2.4 2 0 0 2 2 2 1 SAC3/GANP family SAC3 PF12209.8 CCD26980.1 - 7e-24 83.8 1.3 4.1e-23 81.4 1.3 2.5 1 0 0 1 1 1 1 Leucine permease transcriptional regulator helical domain Sfi1 PF08457.10 CCD26980.1 - 4.7 5.6 16.5 0.0071 14.9 3.2 2.2 1 1 1 2 2 2 0 Sfi1 spindle body protein Semialdhyde_dhC PF02774.18 CCD26981.1 - 1.2e-44 152.6 0.0 1.9e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 CCD26981.1 - 4.5e-31 107.8 0.0 7.8e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CCD26981.1 - 0.022 15.0 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 CCD26981.1 - 0.046 14.4 0.0 0.12 13.0 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_10 PF13460.6 CCD26981.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding RNA_polI_A14 PF08203.11 CCD26982.1 - 5e-27 94.4 3.4 5.1e-27 94.4 0.1 2.1 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 Pro_isomerase PF00160.21 CCD26983.1 - 5e-48 163.4 0.0 5.5e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 CCD26983.1 - 0.074 13.1 0.0 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin domain DUF3589 PF12141.8 CCD26984.1 - 1.8e-75 254.5 7.6 3.2e-54 184.3 0.0 2.7 1 1 1 2 2 2 2 Beta-mannosyltransferases MogR_DNAbind PF12181.8 CCD26984.1 - 0.009 15.9 4.0 0.024 14.6 4.0 1.7 1 0 0 1 1 1 1 DNA binding domain of the motility gene repressor (MogR) TM231 PF10149.9 CCD26984.1 - 0.061 12.7 0.7 0.14 11.5 0.1 1.7 1 1 0 1 1 1 0 Transmembrane protein 231 ENTH PF01417.20 CCD26985.1 - 9.2e-33 113.0 0.7 4.1e-32 110.8 0.0 2.2 2 0 0 2 2 2 1 ENTH domain Ycf54 PF10674.9 CCD26985.1 - 0.52 10.6 3.1 2.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2488) RWD PF05773.22 CCD26986.1 - 1.9e-25 89.4 6.1 3.8e-25 88.4 6.1 1.5 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 CCD26986.1 - 2.1e-05 24.9 6.3 2.1e-05 24.9 6.3 2.7 2 1 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 CCD26987.1 - 4e-17 61.7 16.7 1.3e-09 37.7 2.8 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CCD26987.1 - 1.2e-07 31.6 20.2 2.8e-05 24.0 4.1 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CCD26987.1 - 5.7e-06 26.0 15.6 4.2e-05 23.2 1.3 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 CCD26987.1 - 0.041 14.6 1.8 0.041 14.6 1.8 3.5 3 1 1 4 4 4 0 Torus domain zf-CCCH_2 PF14608.6 CCD26987.1 - 0.073 13.6 14.6 0.48 11.0 1.2 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Defensin_int PF17858.1 CCD26987.1 - 0.41 10.7 1.7 0.82 9.7 0.7 1.9 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide Mcp5_PH PF12814.7 CCD26988.1 - 3.6e-43 146.6 0.0 9.8e-43 145.2 0.0 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 CCD26988.1 - 0.00033 21.1 0.0 0.0041 17.6 0.0 2.9 2 0 0 2 2 2 1 PH domain PH_2 PF08458.10 CCD26988.1 - 0.0092 16.3 0.1 0.57 10.6 0.0 2.7 2 0 0 2 2 2 1 Plant pleckstrin homology-like region Ribosomal_L30_N PF08079.12 CCD26988.1 - 0.55 10.5 2.8 2.5 8.4 0.0 3.1 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain COX_ARM PF06481.14 CCD26988.1 - 3.4 7.7 8.6 1.7 8.6 0.4 4.9 4 0 0 4 4 4 0 COX Aromatic Rich Motif SpoU_sub_bind PF08032.12 CCD26988.1 - 3.8 7.8 5.3 29 5.0 0.0 4.4 4 0 0 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding DUF771 PF05595.11 CCD26988.1 - 6.2 6.9 41.0 1.1 9.2 0.1 13.2 15 1 1 16 16 16 0 Domain of unknown function (DUF771) 2-oxoacid_dh PF00198.23 CCD26989.1 - 9.8e-79 264.1 0.0 1.4e-78 263.6 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CCD26989.1 - 2e-16 59.6 0.7 3.5e-16 58.8 0.7 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CCD26989.1 - 1.9e-05 24.4 0.3 0.11 12.3 0.0 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 CCD26989.1 - 0.00035 20.4 0.1 0.00085 19.2 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.6 CCD26989.1 - 0.0047 17.6 0.1 0.12 13.1 0.1 2.3 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.6 CCD26989.1 - 0.026 14.4 0.0 0.077 13.0 0.0 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 CCD26989.1 - 0.089 12.5 0.2 1.1 9.0 0.1 2.3 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_D23 PF16576.5 CCD26989.1 - 0.11 11.7 1.3 0.25 10.5 1.1 1.8 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion CPSF100_C PF13299.6 CCD26989.1 - 0.16 12.2 5.8 0.36 11.0 3.2 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 CCD26989.1 - 1.9 7.2 3.7 2.7 6.7 3.7 1.1 1 0 0 1 1 1 0 Presenilin DUF4674 PF15719.5 CCD26989.1 - 4.4 7.3 11.7 8.9 6.3 11.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) Choline_kinase PF01633.20 CCD26990.1 - 4.6e-50 170.2 0.1 7.3e-50 169.5 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CCD26990.1 - 9.2e-08 32.3 0.0 2.1e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 CCD26990.1 - 0.00098 18.5 0.1 0.0017 17.7 0.1 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kin_N PF04428.14 CCD26990.1 - 0.0028 17.3 0.0 0.0072 16.0 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus zf-C2H2 PF00096.26 CCD26991.1 - 9.2e-09 35.3 11.1 0.00086 19.6 1.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD26991.1 - 0.0075 17.0 11.2 1.3 10.1 0.8 3.8 2 1 1 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCD26991.1 - 0.0079 16.6 0.1 0.0079 16.6 0.1 3.7 3 0 0 3 3 3 1 Zinc-finger double domain MalF_P2 PF14785.6 CCD26991.1 - 0.12 12.5 6.8 0.28 11.2 6.8 1.6 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain AT_hook PF02178.19 CCD26991.1 - 0.12 12.3 5.2 0.36 10.9 5.2 1.9 1 0 0 1 1 1 0 AT hook motif zf-C2H2_jaz PF12171.8 CCD26991.1 - 8.9 6.7 9.0 1.2e+02 3.1 0.0 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DHHC PF01529.20 CCD26992.1 - 1.7e-25 89.7 15.5 1.7e-25 89.7 15.5 3.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase PGG PF13962.6 CCD26992.1 - 1.1 9.1 3.7 0.49 10.2 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF2975 PF11188.8 CCD26992.1 - 6.2 6.7 7.8 6 6.8 4.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) Zip PF02535.22 CCD26993.1 - 1.1e-78 264.8 7.4 1.3e-78 264.6 7.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Tetraspanin PF00335.20 CCD26993.1 - 0.041 13.6 0.8 0.48 10.1 0.0 2.6 2 0 0 2 2 2 0 Tetraspanin family Cation_ATPase_C PF00689.21 CCD26993.1 - 3.2 7.4 12.3 0.41 10.3 0.9 3.1 3 1 0 3 3 3 0 Cation transporting ATPase, C-terminus TFIID_20kDa PF03847.13 CCD26994.1 - 2.2e-31 108.2 0.2 4.6e-31 107.1 0.2 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 CCD26994.1 - 0.0049 16.9 1.1 0.094 12.8 0.0 3.0 3 0 0 3 3 3 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 CCD26994.1 - 0.0051 17.2 0.0 0.0051 17.2 0.0 3.7 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 DUF2664 PF10867.8 CCD26994.1 - 0.014 15.8 3.9 0.015 15.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) K_channel_TID PF07941.11 CCD26994.1 - 0.99 9.9 17.9 5 7.7 2.0 3.8 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain SirA PF10747.9 CCD26994.1 - 9.6 6.5 13.5 0.18 12.2 4.3 2.5 2 0 0 2 2 2 0 Sporulation inhibitor of replication protein SirA Asp PF00026.23 CCD26995.1 - 3.2e-71 240.3 5.5 5.9e-61 206.6 2.8 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCD26995.1 - 6e-11 42.9 0.8 1.6e-05 25.2 0.0 2.6 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal EXS PF03124.14 CCD26995.1 - 0.021 14.1 0.1 0.033 13.5 0.1 1.2 1 0 0 1 1 1 0 EXS family TAXi_C PF14541.6 CCD26995.1 - 0.1 12.4 0.3 1.8 8.4 0.3 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Cwf_Cwc_15 PF04889.12 CCD26995.1 - 0.16 11.7 1.3 0.25 11.0 1.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 CCD26996.1 - 3e-12 46.8 13.3 0.0056 17.5 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD26996.1 - 0.025 14.9 0.1 6.6 7.1 0.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Dopey_N PF04118.14 CCD26997.1 - 4.7e-108 360.9 4.9 4.7e-108 360.9 4.9 3.3 3 0 0 3 3 3 1 Dopey, N-terminal Ku PF02735.16 CCD26997.1 - 0.059 13.1 0.3 0.9 9.2 0.1 2.5 2 0 0 2 2 2 0 Ku70/Ku80 beta-barrel domain MTS PF05175.14 CCD26998.1 - 1.9e-05 24.2 0.0 0.00014 21.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CCD26998.1 - 0.00067 19.5 0.0 0.011 15.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCD26998.1 - 0.0037 18.0 0.0 0.028 15.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_33 PF10017.9 CCD26998.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DUF2431 PF10354.9 CCD26998.1 - 0.064 13.5 0.0 0.1 12.8 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2431) rRNA_methylase PF06962.12 CCD26998.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative rRNA methylase ubiquitin PF00240.23 CCD26999.1 - 3.3e-23 81.2 0.2 3.7e-23 81.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CCD26999.1 - 7e-14 51.4 0.1 7.6e-14 51.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CCD26999.1 - 0.0065 16.4 0.0 0.0072 16.2 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 CCD26999.1 - 0.0073 16.7 0.1 0.022 15.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TUG-UBL1 PF11470.8 CCD26999.1 - 0.019 15.2 0.0 0.021 15.0 0.0 1.1 1 0 0 1 1 1 0 TUG ubiquitin-like domain efThoc1 PF11957.8 CCD27001.1 - 9.9e-93 311.4 34.6 9.9e-93 311.4 34.6 2.1 1 1 1 2 2 2 1 THO complex subunit 1 transcription elongation factor S-antigen PF05756.11 CCD27001.1 - 0.0077 16.6 2.3 0.0077 16.6 2.3 4.0 2 1 1 3 3 3 1 S-antigen protein adh_short PF00106.25 CCD27002.1 - 1.6e-10 40.7 0.0 1.6e-08 34.3 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CCD27002.1 - 0.00013 21.7 0.0 0.025 14.2 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase FIN1 PF17300.2 CCD27003.1 - 8.6e-44 149.9 18.5 1.2e-43 149.4 18.5 1.2 1 0 0 1 1 1 1 Filaments in between nuclei protein-1 DUF3246 PF11596.8 CCD27003.1 - 0.022 14.2 0.6 0.036 13.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Flu_C_NS2 PF03555.14 CCD27003.1 - 0.085 13.0 0.5 0.21 11.8 0.1 1.9 2 0 0 2 2 2 0 Influenza C non-structural protein (NS2) F-box-like PF12937.7 CCD27004.1 - 0.013 15.4 0.2 0.04 13.8 0.2 1.9 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 CCD27004.1 - 0.079 12.8 0.1 15 5.5 0.0 2.7 2 0 0 2 2 2 0 F-box ACP53EA PF06313.11 CCD27004.1 - 0.11 12.7 1.7 0.26 11.5 0.0 2.5 4 0 0 4 4 4 0 Drosophila ACP53EA protein BTB_2 PF02214.22 CCD27005.1 - 1.7e-08 34.7 0.2 0.0039 17.5 0.0 3.3 2 1 0 2 2 2 2 BTB/POZ domain Flocculin_t3 PF13928.6 CCD27006.1 - 2.6e-12 47.0 16.9 2.6e-12 47.0 16.9 2.8 2 1 0 2 2 2 1 Flocculin type 3 repeat ABC_membrane PF00664.23 CCD27007.1 - 6e-89 298.3 43.4 6e-48 163.9 17.6 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CCD27007.1 - 3.4e-51 173.4 0.2 1.8e-31 109.5 0.1 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CCD27007.1 - 5.9e-09 35.7 6.8 0.0029 17.1 0.2 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CCD27007.1 - 1.5e-06 28.3 0.3 0.099 12.7 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 CCD27007.1 - 1.9e-05 24.3 0.3 0.098 12.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCD27007.1 - 0.00031 20.7 0.0 0.46 10.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CCD27007.1 - 0.0013 19.1 0.0 2.8 8.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CCD27007.1 - 0.0033 17.3 3.3 0.43 10.3 0.1 3.1 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 CCD27007.1 - 0.0037 17.4 1.5 0.6 10.2 0.1 2.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_15 PF13175.6 CCD27007.1 - 0.0054 16.5 5.1 0.57 9.8 0.0 3.5 4 1 0 4 4 3 1 AAA ATPase domain AAA_22 PF13401.6 CCD27007.1 - 0.007 16.6 1.1 2.5 8.4 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CCD27007.1 - 0.012 16.1 8.9 0.1 13.1 0.0 3.3 4 0 0 4 4 3 0 AAA domain AIG1 PF04548.16 CCD27007.1 - 0.013 14.8 1.1 0.35 10.2 0.0 2.9 3 0 0 3 3 3 0 AIG1 family AAA_25 PF13481.6 CCD27007.1 - 0.019 14.6 0.0 1.9 8.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CCD27007.1 - 0.025 14.1 0.1 3.6 7.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 CCD27007.1 - 0.031 14.4 0.7 1.8 8.6 0.0 2.9 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 CCD27007.1 - 0.033 13.9 0.2 1.4 8.6 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF5336 PF17270.2 CCD27007.1 - 0.037 13.7 0.3 0.11 12.1 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Root_cap PF06830.11 CCD27007.1 - 0.051 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Root cap TsaE PF02367.17 CCD27007.1 - 0.087 12.8 0.5 20 5.2 0.0 3.3 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CCD27007.1 - 0.095 12.0 0.1 9.8 5.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin TMEM132D_C PF15706.5 CCD27007.1 - 0.11 12.3 0.1 0.76 9.6 0.0 2.4 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TrwB_AAD_bind PF10412.9 CCD27007.1 - 0.12 11.3 0.3 2.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 CCD27007.1 - 0.12 11.5 2.2 4.9 6.2 0.1 3.2 3 0 0 3 3 3 0 NB-ARC domain AAA_30 PF13604.6 CCD27007.1 - 0.12 12.0 0.5 22 4.7 0.1 2.8 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 CCD27007.1 - 0.13 12.5 4.2 6.1 7.1 0.0 3.6 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CCD27007.1 - 0.18 11.4 0.6 1.7 8.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rgp1 PF08737.10 CCD27009.1 - 9.8e-109 364.3 10.4 9.8e-109 364.3 10.4 2.1 2 0 0 2 2 2 2 Rgp1 Zn_ribbon_17 PF17120.5 CCD27010.1 - 9.3e-21 73.2 13.5 5.1e-20 70.9 14.0 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 CCD27010.1 - 4.2e-08 33.7 19.4 5.4e-05 23.9 0.1 6.1 5 0 0 5 5 5 2 WD domain, G-beta repeat RWD PF05773.22 CCD27010.1 - 0.0018 18.6 0.0 0.0046 17.2 0.0 1.7 1 0 0 1 1 1 1 RWD domain zf-rbx1 PF12678.7 CCD27010.1 - 0.0035 17.6 7.3 0.0083 16.4 7.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CCD27010.1 - 0.008 16.5 8.3 0.017 15.4 8.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CCD27010.1 - 0.011 15.6 7.0 0.021 14.7 7.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_2 PF03107.16 CCD27010.1 - 0.042 14.2 2.7 0.13 12.6 2.7 1.8 1 0 0 1 1 1 0 C1 domain C1_1 PF00130.22 CCD27010.1 - 0.048 13.6 3.9 0.11 12.4 3.9 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Lyase_1 PF00206.20 CCD27010.1 - 0.091 12.1 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Lyase Phage_min_tail PF05939.13 CCD27010.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Phage minor tail protein Prok-RING_1 PF14446.6 CCD27010.1 - 0.31 11.0 5.6 0.61 10.1 5.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zinc_ribbon_16 PF17034.5 CCD27010.1 - 0.39 10.9 8.2 1 9.6 8.2 1.7 1 0 0 1 1 1 0 Zinc-ribbon like family EPSP_synthase PF00275.20 CCD27011.1 - 1.7e-137 458.5 0.0 2.5e-137 458.0 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 CCD27011.1 - 2.6e-98 328.4 0.0 3.9e-98 327.8 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 CCD27011.1 - 6.8e-06 26.0 0.1 1.4e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Abhydrolase_1 PF00561.20 CCD27012.1 - 9.5e-20 71.3 0.1 6.4e-19 68.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCD27012.1 - 1.7e-12 48.5 0.0 2.7e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCD27012.1 - 1.7e-09 37.3 0.0 2.1e-06 27.2 0.0 3.0 3 0 0 3 3 3 2 Serine aminopeptidase, S33 DUF915 PF06028.11 CCD27012.1 - 1.9e-09 37.2 3.4 2.2e-08 33.8 3.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 CCD27012.1 - 0.0002 21.0 0.0 0.00085 18.9 0.0 1.9 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Thioesterase PF00975.20 CCD27012.1 - 0.00064 19.9 0.0 0.0036 17.4 0.0 2.2 3 0 0 3 3 3 1 Thioesterase domain Esterase PF00756.20 CCD27012.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.11 CCD27012.1 - 0.0064 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 CCD27012.1 - 0.012 14.6 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Spore_GerAC PF05504.11 CCD27012.1 - 0.023 14.9 0.1 0.051 13.8 0.1 1.5 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Ndr PF03096.14 CCD27012.1 - 0.024 13.4 0.0 0.43 9.2 0.0 2.1 2 0 0 2 2 2 0 Ndr family DLH PF01738.18 CCD27012.1 - 0.031 13.8 0.0 0.083 12.4 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family PGAP1 PF07819.13 CCD27012.1 - 0.034 13.9 0.5 0.18 11.5 0.0 2.0 1 1 1 2 2 2 0 PGAP1-like protein Palm_thioest PF02089.15 CCD27012.1 - 0.041 13.7 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 CCD27012.1 - 0.058 13.2 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CCD27012.1 - 0.085 12.7 0.0 0.54 10.1 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 CCD27013.1 - 6.8e-18 65.2 0.3 1e-15 58.1 0.0 2.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCD27013.1 - 6.6e-09 36.7 0.0 1.1e-08 36.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 CCD27013.1 - 1.6e-08 34.2 0.3 3.6e-08 33.0 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 CCD27013.1 - 2.1e-08 33.8 0.0 0.0003 20.1 0.0 3.2 3 0 0 3 3 3 2 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 CCD27013.1 - 0.00029 20.5 0.4 0.013 15.0 0.0 2.2 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Thioesterase PF00975.20 CCD27013.1 - 0.0012 19.0 0.0 0.025 14.7 0.0 2.6 3 0 0 3 3 3 1 Thioesterase domain Chlorophyllase PF07224.11 CCD27013.1 - 0.0036 16.4 0.0 0.0066 15.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase PGAP1 PF07819.13 CCD27013.1 - 0.0075 16.0 0.0 0.022 14.5 0.0 1.7 1 1 1 2 2 2 1 PGAP1-like protein Esterase PF00756.20 CCD27013.1 - 0.0082 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 CCD27013.1 - 0.012 14.4 0.0 0.036 12.8 0.0 1.8 2 0 0 2 2 2 0 Ndr family Ser_hydrolase PF06821.13 CCD27013.1 - 0.024 14.5 0.0 0.095 12.5 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase Palm_thioest PF02089.15 CCD27013.1 - 0.044 13.6 0.2 0.097 12.5 0.0 1.8 2 0 0 2 2 2 0 Palmitoyl protein thioesterase Chlorophyllase2 PF12740.7 CCD27013.1 - 0.045 12.7 0.0 0.088 11.7 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 CCD27013.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2841 PF11001.8 CCD27014.1 - 1.8e-35 121.7 1.4 3.2e-35 120.9 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) SUIM_assoc PF16619.5 CCD27015.1 - 0.011 15.7 3.5 0.032 14.3 3.5 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 HLH PF00010.26 CCD27015.1 - 0.084 12.8 0.6 0.28 11.2 0.6 2.0 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain PRESAN PF09687.10 CCD27015.1 - 1.5 9.4 6.7 0.51 10.9 2.9 2.2 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Polo_box_2 PF18531.1 CCD27016.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Polo box domain Pkinase PF00069.25 CCD27017.1 - 3.1e-67 226.7 8.8 1e-63 215.2 0.2 3.1 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD27017.1 - 8.4e-39 133.4 0.2 7e-36 123.8 0.0 2.6 1 1 1 2 2 2 2 Protein tyrosine kinase KA1 PF02149.19 CCD27017.1 - 6.2e-18 64.3 0.9 1.6e-17 63.0 0.0 2.2 3 0 0 3 3 3 1 Kinase associated domain 1 Kinase-like PF14531.6 CCD27017.1 - 2.1e-08 33.8 2.7 2.2e-08 33.7 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 CCD27017.1 - 0.00015 21.2 0.1 0.00036 19.9 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCD27017.1 - 0.0034 17.3 0.1 0.018 15.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family CBFD_NFYB_HMF PF00808.23 CCD27018.1 - 3.9e-05 23.9 0.1 8.1e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CCD27018.1 - 0.00022 21.3 0.4 0.00036 20.6 0.4 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CCD27018.1 - 0.0018 18.6 0.2 0.0018 18.6 0.2 3.0 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 ALMT PF11744.8 CCD27018.1 - 8.6 5.1 9.0 11 4.7 9.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter ANAPC4 PF12896.7 CCD27019.1 - 5.4e-20 71.8 12.7 1.1e-19 70.8 12.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 MFS_1 PF07690.16 CCD27020.1 - 1.1e-12 47.5 41.4 1.1e-12 47.5 41.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRM PF02005.16 CCD27022.1 - 1.4e-145 485.2 0.1 1.8e-145 484.9 0.1 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 CCD27022.1 - 0.00014 21.7 0.1 0.00027 20.8 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein DUF2067 PF09840.9 CCD27022.1 - 0.026 14.1 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Mic1 PF07035.12 CCD27022.1 - 0.071 12.8 0.1 7.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like SUI1 PF01253.22 CCD27023.1 - 8.4e-18 64.7 0.3 2.5e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 CCD27023.1 - 2.7e-09 37.6 2.5 3.7e-09 37.1 0.8 2.2 2 0 0 2 2 2 1 Pre-PUA-like domain SWIB PF02201.18 CCD27023.1 - 0.00012 21.9 0.2 0.00039 20.2 0.2 1.9 1 0 0 1 1 1 1 SWIB/MDM2 domain Med4 PF10018.9 CCD27024.1 - 1.3e-30 106.5 16.9 1.1e-29 103.5 16.3 2.3 2 1 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Presenilin PF01080.17 CCD27024.1 - 8.6 5.0 10.8 16 4.1 10.8 1.3 1 0 0 1 1 1 0 Presenilin Ribosomal_L1 PF00687.21 CCD27025.1 - 9.7e-24 84.2 0.4 1.4e-23 83.7 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L34 PF00468.17 CCD27026.1 - 1.5e-18 66.4 6.6 2.3e-18 65.8 6.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 MASE3 PF17159.4 CCD27026.1 - 0.077 12.6 0.0 0.096 12.3 0.0 1.1 1 0 0 1 1 1 0 Membrane-associated sensor domain Securin PF04856.13 CCD27027.1 - 1.3e-16 61.3 22.3 7.1e-16 58.9 22.4 2.1 1 1 0 1 1 1 1 Securin sister-chromatid separation inhibitor Aminotran_1_2 PF00155.21 CCD27028.1 - 1e-35 123.6 0.0 1.6e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CCD27028.1 - 0.057 12.7 0.0 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Beta-eliminating lyase SRP1_TIP1 PF00660.17 CCD27029.1 - 2.9e-32 110.7 0.2 3.5e-32 110.4 0.2 1.2 1 0 0 1 1 1 1 Seripauperin and TIP1 family zf-RING_13 PF17977.1 CCD27030.1 - 0.18 12.0 0.7 0.36 11.0 0.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Gaa1 PF04114.14 CCD27031.1 - 1e-121 407.4 16.1 3.7e-121 405.6 16.1 1.7 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component FGGY_C PF02782.16 CCD27032.1 - 4.8e-52 176.6 0.1 7e-52 176.0 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CCD27032.1 - 7.2e-20 71.6 0.2 2.1e-19 70.1 0.2 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 CCD27032.1 - 0.013 15.4 0.0 0.033 14.1 0.0 1.6 2 0 0 2 2 2 0 Hexokinase TRAPPC-Trs85 PF12739.7 CCD27033.1 - 3.9e-108 362.0 3.0 6.2e-108 361.4 3.0 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit EMP70 PF02990.16 CCD27034.1 - 1.6e-175 584.8 12.1 2.3e-175 584.2 12.1 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Actin PF00022.19 CCD27036.1 - 2.9e-05 22.8 0.0 0.00016 20.4 0.0 1.9 1 1 1 2 2 2 1 Actin Actin_micro PF17003.5 CCD27036.1 - 0.0054 16.0 0.1 0.0072 15.6 0.1 1.2 1 0 0 1 1 1 1 Putative actin-like family Mor PF08765.11 CCD27036.1 - 0.16 12.0 0.0 0.56 10.2 0.0 1.9 2 0 0 2 2 2 0 Mor transcription activator family Serinc PF03348.15 CCD27037.1 - 7.3e-138 460.1 14.5 8.5e-138 459.9 14.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) TMEM173 PF15009.6 CCD27037.1 - 0.27 10.4 7.1 0.028 13.6 2.2 1.8 2 0 0 2 2 2 0 Transmembrane protein 173 PH_4 PF15404.6 CCD27038.1 - 1.4e-79 266.1 0.1 3.3e-79 264.9 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.6 CCD27038.1 - 5.5e-25 86.8 2.1 1.9e-24 85.1 0.2 2.8 2 0 0 2 2 2 1 Sporulation protein family 7 PH PF00169.29 CCD27038.1 - 0.00065 20.2 1.9 0.59 10.7 0.0 4.7 4 1 0 4 4 4 1 PH domain DUF1610 PF07754.11 CCD27038.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Nrap PF03813.14 CCD27038.1 - 1.1 9.2 6.6 0.11 12.5 0.4 2.3 2 0 0 2 2 2 0 Nrap protein domain 1 Ste5_C PF12194.8 CCD27039.1 - 7.5e-85 283.7 3.3 2.2e-84 282.2 3.3 1.8 1 0 0 1 1 1 1 Protein kinase Fus3-binding PH_10 PF15411.6 CCD27039.1 - 0.022 15.0 0.0 0.073 13.3 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain zf-RING_11 PF17123.5 CCD27039.1 - 0.045 13.5 1.4 0.13 12.1 1.4 1.8 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 CCD27039.1 - 0.13 11.9 0.2 0.25 11.0 0.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 CCD27039.1 - 0.14 12.5 5.7 0.22 11.9 4.7 1.9 1 1 0 1 1 1 0 Ring finger domain PHD PF00628.29 CCD27039.1 - 1 9.3 3.0 2.3 8.2 3.0 1.6 1 0 0 1 1 1 0 PHD-finger Peptidase_M24 PF00557.24 CCD27040.1 - 4.6e-06 26.5 0.0 1.2e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Metallopeptidase family M24 COPI_assoc PF08507.10 CCD27041.1 - 1.6e-35 122.0 9.1 1.8e-35 121.8 9.1 1.0 1 0 0 1 1 1 1 COPI associated protein TMEM72 PF16054.5 CCD27041.1 - 0.012 15.4 2.0 0.049 13.3 2.0 1.9 1 1 0 1 1 1 0 Transmembrane protein family 72 SLATT_5 PF18160.1 CCD27041.1 - 7.9 5.8 12.9 1.8 7.9 5.0 2.0 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 14-3-3 PF00244.20 CCD27042.1 - 4e-106 353.5 4.4 4.5e-106 353.3 4.4 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 CCD27042.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF SLIDE PF09111.10 CCD27042.1 - 0.076 13.0 0.6 0.16 12.0 0.1 1.8 2 0 0 2 2 2 0 SLIDE FRG PF08867.11 CCD27042.1 - 0.14 13.1 1.1 0.25 12.3 0.3 2.0 2 1 0 2 2 2 0 FRG domain MCM6_C PF18263.1 CCD27042.1 - 0.57 10.4 4.9 0.44 10.8 0.6 2.6 3 0 0 3 3 3 0 MCM6 C-terminal winged-helix domain Glutaredoxin PF00462.24 CCD27043.1 - 7.5e-18 64.5 1.1 1.1e-16 60.8 0.0 2.7 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin PF00085.20 CCD27043.1 - 2.6e-13 49.8 0.0 6.7e-13 48.5 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 CCD27043.1 - 2.3e-05 23.9 0.1 2.8e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CCD27043.1 - 2.7e-05 24.4 0.1 0.0064 16.8 0.1 2.7 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 CCD27043.1 - 0.01 16.0 0.0 0.025 14.7 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.6 CCD27043.1 - 0.011 16.1 0.0 0.1 13.1 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin-like domain P22_CoatProtein PF11651.8 CCD27043.1 - 0.018 13.6 0.2 0.023 13.3 0.2 1.1 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 AAA_23 PF13476.6 CCD27043.1 - 0.065 13.7 2.4 0.086 13.3 2.4 1.2 1 0 0 1 1 1 0 AAA domain DUF4820 PF16091.5 CCD27043.1 - 0.092 12.1 2.1 0.14 11.5 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) MutS_V PF00488.21 CCD27044.1 - 2.7e-65 219.9 0.1 5.2e-65 219.0 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CCD27044.1 - 4.6e-34 118.3 0.6 4.6e-34 118.3 0.6 2.3 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 CCD27044.1 - 7.7e-32 109.9 0.0 3.1e-31 107.9 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 CCD27044.1 - 5.7e-16 58.6 0.0 1.5e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 CCD27044.1 - 1.2e-12 48.2 0.0 4.8e-12 46.3 0.0 2.0 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 CCD27044.1 - 0.024 14.2 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CCD27044.1 - 0.1 12.4 0.0 0.36 10.6 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoLip_ATPase_C PF16212.5 CCD27045.1 - 6.6e-74 248.8 30.6 6.6e-74 248.8 30.6 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCD27045.1 - 2.8e-18 65.4 0.8 8.9e-18 63.7 0.8 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CCD27045.1 - 1.2e-12 47.8 0.1 5.3e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CCD27045.1 - 4.2e-09 37.0 2.5 5.1e-05 23.7 0.9 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CCD27045.1 - 2.2e-05 24.1 0.2 8.5e-05 22.1 0.2 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CCD27045.1 - 0.0021 17.9 0.2 0.0049 16.6 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4064 PF13273.6 CCD27045.1 - 4.8 7.5 6.7 5.3 7.4 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) UQ_con PF00179.26 CCD27046.1 - 1.2e-48 164.3 0.0 1.3e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CCD27046.1 - 0.016 15.1 0.1 0.029 14.2 0.1 1.5 1 1 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 CCD27046.1 - 0.036 13.8 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 CCD27046.1 - 0.05 13.9 0.1 0.067 13.5 0.1 1.4 1 0 0 1 1 1 0 RWD domain SNF2_N PF00176.23 CCD27047.1 - 8.2e-63 212.2 0.0 1.6e-62 211.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cdh1_DBD_1 PF18196.1 CCD27047.1 - 1.1e-45 154.8 5.5 1.1e-45 154.8 5.5 3.0 3 0 0 3 3 1 1 Chromodomain helicase DNA-binding domain 1 DUF4208 PF13907.6 CCD27047.1 - 6.1e-26 90.7 1.8 6.1e-26 90.7 1.8 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 CCD27047.1 - 1.1e-20 74.0 0.8 6.1e-20 71.6 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Chromo PF00385.24 CCD27047.1 - 1.5e-20 72.8 5.1 5.5e-13 48.6 0.2 3.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 CCD27047.1 - 2.2e-07 31.0 0.9 1.4e-06 28.4 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 CCD27047.1 - 0.00044 20.4 0.0 0.0033 17.6 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.10 CCD27047.1 - 0.0031 17.5 0.5 0.04 13.9 0.0 3.2 4 0 0 4 4 4 1 SLIDE CHDCT2 PF08074.11 CCD27047.1 - 0.0036 17.5 0.0 0.042 14.0 0.0 2.8 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain Myb_DNA-bind_6 PF13921.6 CCD27047.1 - 0.025 14.8 0.5 0.12 12.6 0.0 2.6 3 0 0 3 3 3 0 Myb-like DNA-binding domain PheRS_DBD3 PF18553.1 CCD27047.1 - 0.033 14.5 0.4 0.21 11.9 0.5 2.3 2 0 0 2 2 2 0 PheRS DNA binding domain 3 Ribosomal_L26 PF16906.5 CCD27048.1 - 1.9e-37 127.5 1.7 2.5e-37 127.2 1.7 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CCD27048.1 - 0.00015 21.6 1.4 0.00018 21.3 0.4 1.7 2 0 0 2 2 2 1 KOW motif Glyco_hydro_72 PF03198.14 CCD27049.1 - 8.1e-139 462.2 3.3 1e-138 461.9 3.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 CCD27049.1 - 4.8e-15 56.0 0.2 9.8e-15 55.0 0.2 1.6 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 CCD27049.1 - 0.027 13.9 0.1 0.1 12.0 0.1 1.9 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Glucan_synthase PF02364.15 CCD27050.1 - 0 1349.7 0.0 0 1349.2 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CCD27050.1 - 3.9e-43 146.9 0.2 3.9e-43 146.9 0.2 2.2 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF3671 PF12420.8 CCD27050.1 - 0.25 11.4 0.0 0.25 11.4 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function Ribosomal_S25 PF03297.15 CCD27052.1 - 1.9e-39 133.9 7.0 2.2e-39 133.7 7.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FtsK_gamma PF09397.10 CCD27052.1 - 0.00026 20.7 0.1 0.0004 20.1 0.1 1.3 1 0 0 1 1 1 1 Ftsk gamma domain EAP30 PF04157.16 CCD27052.1 - 0.032 13.5 0.1 0.037 13.3 0.1 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_CodY PF08222.11 CCD27052.1 - 0.036 13.6 0.1 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_DeoR PF08220.12 CCD27052.1 - 0.082 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Ran_BP1 PF00638.18 CCD27053.1 - 2e-37 128.2 0.1 5.9e-37 126.6 0.1 1.9 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 CCD27053.1 - 1e-12 48.5 0.2 1e-12 48.5 0.2 4.4 5 1 0 5 5 5 1 NUP50 (Nucleoporin 50 kDa) MA3 PF02847.17 CCD27054.1 - 1.5e-27 95.8 0.1 1e-26 93.1 0.0 2.6 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 CCD27054.1 - 1.2e-22 80.6 9.5 1.3e-22 80.5 5.2 2.8 2 1 0 2 2 2 1 MIF4G domain WH2 PF02205.20 CCD27055.1 - 3.7e-14 52.0 1.2 1.1e-10 41.0 0.3 2.5 2 0 0 2 2 2 2 WH2 motif fn3_2 PF16893.5 CCD27056.1 - 6e-41 138.5 0.6 1.4e-40 137.3 0.6 1.7 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 CCD27056.1 - 2.7e-23 81.7 0.3 4.8e-23 80.8 0.3 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 CCD27056.1 - 4.6e-11 42.9 0.0 1.1e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 CCD27056.1 - 0.0064 16.7 0.0 0.0064 16.7 0.0 3.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3006) fn3 PF00041.21 CCD27056.1 - 0.011 16.1 0.0 0.046 14.1 0.0 2.1 1 0 0 1 1 1 0 Fibronectin type III domain BRCT_2 PF16589.5 CCD27056.1 - 0.027 14.9 0.0 0.11 13.0 0.0 2.0 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CCD27056.1 - 0.4 11.0 0.1 0.4 11.0 0.1 2.3 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Peptidase_M55 PF04951.13 CCD27056.1 - 2.5 7.4 11.8 6.6 6.0 11.8 1.7 1 0 0 1 1 1 0 D-aminopeptidase Mid2 PF04478.12 CCD27057.1 - 8.3e-58 194.5 1.7 8.3e-58 194.5 1.7 2.2 2 1 1 3 3 3 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 CCD27057.1 - 0.0012 18.2 2.1 0.0057 16.0 2.1 2.2 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Orf78 PF06024.12 CCD27057.1 - 0.056 13.7 0.1 0.18 12.1 0.1 1.9 1 0 0 1 1 1 0 Orf78 (ac78) MF_alpha_N PF05436.11 CCD27058.1 - 1.8e-34 117.5 0.3 2.2e-34 117.2 0.3 1.1 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus MF_alpha PF04648.12 CCD27058.1 - 3.9e-21 74.4 29.1 8e-07 29.1 5.8 3.2 3 0 0 3 3 3 3 Yeast mating factor alpha hormone CTP_transf_like PF01467.26 CCD27060.1 - 2.2e-31 109.0 0.2 5e-31 107.8 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase-like HABP4_PAI-RBP1 PF04774.15 CCD27061.1 - 0.0012 19.7 0.7 0.0015 19.4 0.7 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family DUF4112 PF13430.6 CCD27062.1 - 4.5e-27 94.4 0.2 5.9e-27 94.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF4014 PF13198.6 CCD27062.1 - 0.17 12.3 0.3 4.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) Cytochrome_B PF00033.19 CCD27062.1 - 0.46 10.3 2.8 2.6 7.8 0.3 2.1 1 1 1 2 2 2 0 Cytochrome b/b6/petB Pex24p PF06398.11 CCD27063.1 - 5.6e-88 295.4 13.6 9.3e-88 294.7 13.6 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin zf-CCCH PF00642.24 CCD27064.1 - 3.5e-10 39.5 3.2 7.3e-10 38.5 3.2 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 CCD27064.1 - 7.3e-10 38.6 6.9 1.3e-09 37.7 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCD27064.1 - 3.1e-08 33.5 4.2 8.8e-08 32.0 4.3 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CCD27064.1 - 3.7e-08 33.2 10.8 6.8e-08 32.4 10.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CCD27064.1 - 1.4e-07 31.2 8.3 1.4e-07 31.2 8.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCD27064.1 - 3.5e-07 30.0 6.6 6.7e-07 29.1 6.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf_CCCH_4 PF18345.1 CCD27064.1 - 1.7e-06 27.9 5.6 4.2e-06 26.6 5.6 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4 PF00097.25 CCD27064.1 - 3.1e-06 26.9 11.2 6e-06 26.0 11.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCD27064.1 - 8.7e-06 26.0 8.4 1.8e-05 25.0 8.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 CCD27064.1 - 3.9e-05 23.7 9.3 9.2e-05 22.5 9.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH_4 PF18044.1 CCD27064.1 - 0.00032 20.4 1.8 0.00032 20.4 1.8 1.8 2 0 0 2 2 1 1 CCCH-type zinc finger zf-RING_10 PF16685.5 CCD27064.1 - 0.0051 16.9 4.0 0.0051 16.9 4.0 1.8 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 CCD27064.1 - 0.041 14.2 4.7 0.11 12.8 4.7 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_14 PF17978.1 CCD27064.1 - 0.063 13.7 3.5 0.13 12.7 3.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_4 PF14570.6 CCD27064.1 - 0.22 11.3 6.9 0.95 9.3 4.0 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 CCD27064.1 - 0.62 10.0 7.3 0.11 12.4 3.5 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 CCD27064.1 - 0.68 9.6 6.6 1.3 8.8 6.6 1.4 1 0 0 1 1 1 0 P-11 zinc finger AIP3 PF03915.13 CCD27066.1 - 5.1e-135 450.7 15.8 5.1e-135 450.7 15.8 2.3 2 1 0 2 2 2 1 Actin interacting protein 3 Syntaxin-6_N PF09177.11 CCD27066.1 - 1.9 9.1 8.9 0.95 10.1 3.5 3.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Telomerase_RBD PF12009.8 CCD27067.1 - 1.4e-26 93.1 6.5 2.9e-26 92.2 2.3 3.0 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 CCD27067.1 - 1.3e-08 34.7 5.6 5.1e-08 32.7 0.1 3.2 3 1 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) SNF5 PF04855.12 CCD27068.1 - 8.4e-42 143.6 9.3 3.9e-23 82.5 0.6 2.9 2 1 1 3 3 3 2 SNF5 / SMARCB1 / INI1 SUIM_assoc PF16619.5 CCD27068.1 - 0.0044 17.0 1.8 0.0044 17.0 1.8 3.3 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 DUF1758 PF05585.12 CCD27068.1 - 1.5 8.5 4.3 4.2 7.1 0.1 2.8 1 1 2 3 3 3 0 Putative peptidase (DUF1758) EF1_GNE PF00736.19 CCD27069.1 - 2.3e-33 114.2 1.6 4.3e-33 113.4 1.6 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CCD27069.1 - 3.4e-11 43.4 4.3 3.4e-11 43.4 4.3 3.1 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region DNA_pol3_a_NII PF11490.8 CCD27069.1 - 0.54 10.2 3.0 0.57 10.1 0.2 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Vps8 PF12816.7 CCD27071.1 - 2.7e-52 177.2 0.9 2.7e-52 177.2 0.9 2.9 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 zf-C3H2C3 PF17122.5 CCD27071.1 - 0.034 14.2 2.9 0.042 13.9 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger zf-rbx1 PF12678.7 CCD27071.1 - 0.082 13.2 1.1 0.32 11.3 0.1 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CCD27071.1 - 0.14 12.1 0.1 0.47 10.4 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCD27071.1 - 0.3 11.5 3.3 0.22 11.9 0.3 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 CCD27071.1 - 0.78 9.6 4.1 0.25 11.2 0.7 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) B-block_TFIIIC PF04182.12 CCD27072.1 - 3.2e-18 65.6 0.1 1.3e-17 63.7 0.1 2.2 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC PCI PF01399.27 CCD27072.1 - 0.018 15.5 0.7 0.38 11.3 0.1 3.2 3 0 0 3 3 3 0 PCI domain DUF5401 PF17380.2 CCD27073.1 - 0.1 10.6 0.9 0.1 10.7 0.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) EMP24_GP25L PF01105.24 CCD27075.1 - 2.8e-52 177.3 0.2 3.4e-52 177.0 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 CCD27075.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.6 1 1 0 1 1 1 0 SdrD B-like domain Tospo_nucleocap PF01533.16 CCD27075.1 - 0.068 12.6 0.0 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Tospovirus nucleocapsid protein WD40 PF00400.32 CCD27076.1 - 1.3e-14 54.3 2.4 4.4e-07 30.5 0.5 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD27076.1 - 3.2e-10 40.2 0.9 0.043 14.1 0.0 4.2 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCD27076.1 - 1.7e-05 24.3 0.0 0.001 18.5 0.0 2.6 2 1 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 CCD27076.1 - 0.0005 20.0 0.6 0.06 13.2 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 CCD27076.1 - 0.0069 15.0 0.0 0.032 12.8 0.0 2.1 2 1 1 3 3 3 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 CCD27076.1 - 0.0084 15.1 0.0 1.7 7.5 0.1 2.9 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1623 PF07785.11 CCD27076.1 - 0.047 13.9 1.5 0.065 13.4 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1623) PD40 PF07676.12 CCD27076.1 - 0.78 9.8 3.2 1.2 9.1 0.2 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 CCD27077.1 - 3.1e-16 59.4 20.2 0.0036 18.1 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD27077.1 - 3e-15 56.3 4.4 1.6e-07 31.5 0.1 3.9 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCD27077.1 - 4.2e-06 26.8 0.3 0.033 14.1 0.1 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CCD27077.1 - 0.056 12.4 0.0 0.25 10.3 0.0 2.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Rep_fac-A_C PF08646.10 CCD27078.1 - 6.1e-60 201.2 9.9 7e-58 194.5 3.2 3.0 4 0 0 4 4 4 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CCD27078.1 - 6.5e-36 122.2 0.1 2.1e-29 101.3 0.0 4.3 4 0 0 4 4 4 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 CCD27078.1 - 2.5e-18 65.8 0.2 2.9e-08 33.6 0.0 4.5 4 0 0 4 4 4 4 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 CCD27078.1 - 2.1e-09 37.5 0.1 2.5e-07 30.7 0.0 3.1 3 1 0 3 3 3 1 Cell division control protein 24, OB domain 3 tRNA_anti_2 PF13742.6 CCD27078.1 - 0.00039 20.6 0.0 5.8 7.2 0.0 3.7 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain POT1 PF02765.17 CCD27078.1 - 0.00053 19.8 0.4 1.9 8.3 0.1 3.1 3 0 0 3 3 3 2 Telomeric single stranded DNA binding POT1/CDC13 DUF223 PF02721.14 CCD27078.1 - 0.098 13.0 0.2 0.36 11.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF223 EPL1 PF10513.9 CCD27078.1 - 5.3 7.4 11.1 1.2 9.5 1.7 2.6 2 1 0 2 2 2 0 Enhancer of polycomb-like tRNA_int_endo PF01974.17 CCD27079.1 - 2.2e-12 46.8 0.0 4.2e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain TAL_FSA PF00923.19 CCD27080.1 - 3.7e-100 335.0 1.1 4.2e-100 334.8 1.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase IlvN PF07991.12 CCD27081.1 - 8.8e-46 155.5 0.0 1.2e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 CCD27081.1 - 5.9e-41 140.1 0.1 1.2e-40 139.1 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain eIF2A PF08662.11 CCD27083.1 - 1.9e-75 253.0 0.1 7.2e-75 251.1 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 CCD27083.1 - 0.00031 21.5 1.0 4.4 8.3 0.0 4.7 4 1 1 5 5 5 2 WD domain, G-beta repeat Hyphal_reg_CWP PF11765.8 CCD27084.1 - 7.5e-21 74.4 5.0 1.3e-20 73.6 5.0 1.4 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal G8 PF10162.9 CCD27084.1 - 0.086 12.9 0.9 0.22 11.6 0.9 1.8 1 1 0 1 1 1 0 G8 domain Filament_head PF04732.14 CCD27084.1 - 0.24 12.3 0.0 0.24 12.3 0.0 3.3 2 1 0 2 2 2 0 Intermediate filament head (DNA binding) region AA_permease_2 PF13520.6 CCD27085.1 - 2.5e-83 280.3 47.4 2.9e-83 280.1 47.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCD27085.1 - 8e-21 74.2 43.9 1.1e-20 73.7 43.9 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0182 PF03699.13 CCD27085.1 - 1.5 6.9 8.3 2.3 6.2 8.3 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) BAH PF01426.18 CCD27086.1 - 1.2e-24 86.5 0.1 2.1e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 BAH domain Bromodomain PF00439.25 CCD27086.1 - 4.1e-17 62.0 3.5 8.4e-10 38.6 0.3 3.0 2 0 0 2 2 2 2 Bromodomain Lyase_1 PF00206.20 CCD27087.1 - 2.9e-23 82.8 0.0 4.7e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 CCD27087.1 - 1.6e-17 63.8 0.1 9e-17 61.4 0.0 2.3 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 CCD27087.1 - 0.09 12.5 1.0 0.14 11.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) Amidohydro_1 PF01979.20 CCD27087.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase family PKcGMP_CC PF16808.5 CCD27087.1 - 0.35 10.8 1.8 0.58 10.1 0.4 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase VPS38 PF17649.1 CCD27088.1 - 1.2e-159 531.8 20.3 1.3e-159 531.7 20.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 38 Metallophos PF00149.28 CCD27089.1 - 7.3e-14 52.7 0.1 1.3e-13 51.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 CCD27091.1 - 1.9e-67 227.4 2.0 2.5e-61 207.3 0.4 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD27091.1 - 2.3e-46 158.2 2.1 1.9e-44 151.9 2.1 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 CCD27091.1 - 9.5e-36 122.1 0.6 9.5e-36 122.1 0.6 1.9 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 CCD27091.1 - 2.2e-12 46.9 0.0 1.1e-11 44.6 0.0 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CCD27091.1 - 7.6e-09 35.9 0.1 7.6e-09 35.9 0.1 2.3 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 CCD27091.1 - 6.1e-07 29.0 0.1 2.1e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CCD27091.1 - 0.00073 18.4 1.0 0.00073 18.4 1.0 2.0 2 1 0 2 2 2 1 Fungal protein kinase SAM_4 PF18017.1 CCD27091.1 - 0.036 14.0 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) CUTL PF16557.5 CCD27091.1 - 4.3 7.6 7.7 0.36 11.1 0.2 2.8 2 0 0 2 2 2 0 CUT1-like DNA-binding domain of SATB PIN_4 PF13638.6 CCD27092.1 - 0.023 15.0 0.1 0.073 13.4 0.0 1.9 1 1 0 1 1 1 0 PIN domain SOCS_box PF07525.16 CCD27092.1 - 0.039 14.3 0.0 0.096 13.1 0.0 1.6 1 0 0 1 1 1 0 SOCS box Duffy_binding PF05424.11 CCD27092.1 - 0.069 13.2 1.3 0.099 12.7 0.8 1.5 1 1 0 1 1 1 0 Duffy binding domain Glutaredoxin PF00462.24 CCD27093.1 - 1e-06 28.8 0.0 2.2e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Glutaredoxin CUB PF00431.20 CCD27093.1 - 0.017 15.4 0.1 0.019 15.3 0.1 1.2 1 0 0 1 1 1 0 CUB domain Thioredoxin PF00085.20 CCD27093.1 - 0.037 14.0 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_9 PF14595.6 CCD27093.1 - 0.076 12.8 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin HSP70 PF00012.20 CCD27094.1 - 2e-208 693.4 6.3 2.5e-208 693.1 6.3 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCD27094.1 - 3.6e-18 65.5 0.5 1.5e-15 56.9 0.1 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CCD27094.1 - 0.0025 17.6 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain KASH_CCD PF14662.6 CCD27094.1 - 0.015 15.1 3.0 0.015 15.1 3.0 2.1 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH BcrAD_BadFG PF01869.20 CCD27094.1 - 0.032 13.7 0.0 0.53 9.7 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family P21-Arc PF04062.14 CCD27095.1 - 1.4e-74 249.9 0.1 1.6e-74 249.7 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit ELO PF01151.18 CCD27096.1 - 6.2e-57 193.0 30.5 7.8e-57 192.7 30.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family OAD_gamma PF04277.13 CCD27096.1 - 0.011 16.3 0.7 0.044 14.4 0.7 2.0 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain zf-BED PF02892.15 CCD27097.1 - 4.6e-05 23.4 1.1 0.00011 22.1 1.1 1.6 1 0 0 1 1 1 1 BED zinc finger Ribosomal_S27e PF01667.17 CCD27097.1 - 0.0092 15.7 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S27 Rpr2 PF04032.16 CCD27097.1 - 1.2 9.5 3.8 1 9.7 0.2 2.7 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_4 PF13894.6 CCD27098.1 - 1e-08 35.3 18.9 0.0019 18.9 1.0 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCD27098.1 - 4.6e-08 32.9 5.0 0.00043 20.2 0.4 3.4 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CCD27098.1 - 1.4e-05 25.2 24.1 0.0023 18.3 2.3 5.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 CCD27098.1 - 0.00012 22.3 3.8 0.0013 19.0 1.2 3.4 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 CCD27098.1 - 0.0011 19.3 0.4 0.33 11.5 0.1 3.0 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_jaz PF12171.8 CCD27098.1 - 0.0084 16.4 10.0 0.069 13.5 0.1 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding Rad50_zn_hook PF04423.14 CCD27098.1 - 0.017 14.9 3.1 0.34 10.8 0.2 2.7 1 1 1 2 2 2 0 Rad50 zinc hook motif zf-C2HC_2 PF13913.6 CCD27098.1 - 0.024 14.6 9.3 2 8.4 1.5 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DZR PF12773.7 CCD27098.1 - 0.058 13.4 2.9 0.65 10.1 0.7 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-H2C2_2 PF13465.6 CCD27098.1 - 0.17 12.4 26.8 0.15 12.6 2.3 5.7 4 1 1 5 5 5 0 Zinc-finger double domain zinc_ribbon_9 PF14369.6 CCD27098.1 - 0.2 11.9 2.5 24 5.3 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon ITAM PF02189.15 CCD27098.1 - 0.24 11.9 0.1 0.24 11.9 0.1 2.3 3 0 0 3 3 1 0 Immunoreceptor tyrosine-based activation motif zf-C3HC4_3 PF13920.6 CCD27098.1 - 0.25 11.3 4.7 11 5.9 0.2 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 CCD27098.1 - 0.39 10.7 4.4 23 5.0 0.1 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-met PF12874.7 CCD27098.1 - 0.48 10.9 8.9 4.1 7.9 0.3 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type FYVE PF01363.21 CCD27098.1 - 0.53 10.5 7.6 2 8.6 2.0 3.0 2 1 1 3 3 3 0 FYVE zinc finger zf-RING_5 PF14634.6 CCD27098.1 - 1.2 9.2 4.6 26 4.9 0.1 3.1 3 0 0 3 3 3 0 zinc-RING finger domain zf-ribbon_3 PF13248.6 CCD27098.1 - 2.9 7.4 11.3 4.3 6.9 0.2 3.7 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 CCD27098.1 - 3.9 7.7 7.3 15 5.8 2.8 3.2 2 1 1 3 3 3 0 Zinc ribbon domain DUF2256 PF10013.9 CCD27098.1 - 5.4 7.2 7.9 5.9 7.1 0.5 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) KRE9 PF05390.11 CCD27100.1 - 2.1e-27 95.8 1.2 5.7e-27 94.5 1.2 1.7 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 CCD27100.1 - 7.6e-08 33.0 2.1 8.5e-08 32.8 0.5 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Neurexophilin PF06312.12 CCD27100.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Neurexophilin PSY3 PF16836.5 CCD27101.1 - 3.1e-83 278.6 9.1 3.7e-83 278.4 9.1 1.1 1 0 0 1 1 1 1 Shu complex component Psy3, DNA-binding description FBPase PF00316.20 CCD27102.1 - 7.4e-72 240.8 0.5 9.9e-72 240.4 0.5 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NdhM PF10664.9 CCD27102.1 - 0.084 13.1 0.0 0.36 11.1 0.0 2.0 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M SPT6_acidic PF14632.6 CCD27103.1 - 2.5 8.7 10.7 17 6.1 6.7 2.8 2 1 0 2 2 2 0 Acidic N-terminal SPT6 Vta1 PF04652.16 CCD27104.1 - 6.5e-36 123.5 0.9 6.5e-36 123.5 0.9 2.4 3 0 0 3 3 3 1 Vta1 like Vta1_C PF18097.1 CCD27104.1 - 7.6e-15 54.3 0.8 2.2e-14 52.9 0.8 1.9 1 0 0 1 1 1 1 Vta1 C-terminal domain Ku_N PF03731.15 CCD27104.1 - 0.00033 20.5 0.2 0.00033 20.5 0.2 2.6 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain UPF0175 PF03683.13 CCD27104.1 - 0.042 13.6 2.8 0.068 12.9 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) Peptidase_S49_N PF08496.10 CCD27104.1 - 0.068 13.2 0.5 0.068 13.2 0.5 3.2 3 1 0 3 3 3 0 Peptidase family S49 N-terminal Peptidase_S41 PF03572.18 CCD27104.1 - 0.26 10.9 2.5 0.35 10.4 0.0 2.3 3 0 0 3 3 3 0 Peptidase family S41 AXIN1_TNKS_BD PF16646.5 CCD27104.1 - 1.1 10.3 5.2 0.54 11.2 1.4 2.6 1 1 1 2 2 2 0 Axin-1 tankyrase binding domain SecY PF00344.20 CCD27105.1 - 1.1e-62 212.1 12.6 1.5e-62 211.7 12.6 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CCD27105.1 - 1.1e-17 63.6 0.2 5.5e-17 61.3 0.2 2.4 1 0 0 1 1 1 1 Plug domain of Sec61p DUF2975 PF11188.8 CCD27105.1 - 7.5 6.4 9.7 0.27 11.1 1.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) NTP_transferase PF00483.23 CCD27106.1 - 3e-53 180.9 0.0 5.3e-53 180.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CCD27106.1 - 8.1e-11 41.2 7.7 1.3e-09 37.4 2.2 3.2 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CCD27106.1 - 9.3e-10 39.1 0.0 1.3e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CCD27106.1 - 9.3e-05 22.1 4.7 0.001 18.8 1.2 3.1 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CCD27106.1 - 0.024 13.6 0.0 0.24 10.3 0.1 2.1 2 0 0 2 2 2 0 L-fucokinase DUF4954 PF16314.5 CCD27106.1 - 0.11 10.6 0.1 0.16 10.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) IspD PF01128.19 CCD27106.1 - 0.12 12.1 0.0 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 CCD27106.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase CRAL_TRIO PF00650.20 CCD27107.1 - 1.1e-35 122.7 0.0 1.9e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCD27107.1 - 4.7e-08 33.1 0.1 1.2e-07 31.8 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CCD27107.1 - 5.1e-08 33.2 0.1 1.2e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HTH_WhiA PF02650.14 CCD27107.1 - 0.061 13.7 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 WhiA C-terminal HTH domain Waikav_capsid_1 PF12264.8 CCD27108.1 - 0.21 11.1 2.5 3.3 7.2 0.1 2.8 3 0 0 3 3 3 0 Waikavirus capsid protein 1 tRNA-synt_1 PF00133.22 CCD27109.1 - 4.6e-47 160.6 0.4 1.2e-18 66.8 0.3 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 CCD27109.1 - 2.5e-34 118.4 0.0 4.4e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 CCD27109.1 - 2.9e-26 92.1 1.1 4.7e-18 65.1 0.0 5.1 4 1 1 5 5 5 4 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CCD27109.1 - 1.8e-07 31.3 0.3 3.5e-07 30.3 0.3 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.19 CCD27109.1 - 0.024 13.6 0.1 0.13 11.2 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1e PF01406.19 CCD27109.1 - 0.027 13.8 0.0 0.47 9.7 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain zf-ribbon_3 PF13248.6 CCD27109.1 - 0.053 12.9 2.4 4.4 6.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 CCD27109.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.5 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_S27e PF01667.17 CCD27109.1 - 0.27 11.0 0.6 1.5 8.6 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 SMC_N PF02463.19 CCD27110.1 - 9.7e-27 93.8 3.5 1.5e-25 89.9 3.5 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CCD27110.1 - 2.1e-18 67.6 0.5 2.1e-18 67.6 0.5 5.8 2 2 2 4 4 1 1 AAA domain AAA_15 PF13175.6 CCD27110.1 - 9.5e-14 51.9 11.8 9.5e-14 51.9 11.8 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 CCD27110.1 - 2.9e-06 27.3 12.2 0.0018 18.2 0.2 3.5 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_hinge PF06470.13 CCD27110.1 - 0.0005 20.4 0.0 0.0021 18.4 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain Taxilin PF09728.9 CCD27110.1 - 0.0015 17.8 13.1 0.0015 17.8 13.1 5.4 3 2 2 5 5 4 1 Myosin-like coiled-coil protein Tropomyosin_1 PF12718.7 CCD27110.1 - 0.0022 18.1 4.0 0.0022 18.1 4.0 6.6 3 2 4 7 7 7 1 Tropomyosin like GAS PF13851.6 CCD27110.1 - 0.0025 17.2 6.7 0.0025 17.2 6.7 6.3 2 2 4 6 6 5 3 Growth-arrest specific micro-tubule binding AAA_29 PF13555.6 CCD27110.1 - 0.003 17.3 0.0 0.01 15.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain Ploopntkinase3 PF18751.1 CCD27110.1 - 0.054 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 CCD27110.1 - 0.18 12.3 0.0 0.18 12.3 0.0 5.4 3 2 0 3 3 2 0 ABC transporter Coat_F PF07875.12 CCD27110.1 - 0.59 10.4 3.9 5.6 7.3 0.6 3.0 2 0 0 2 2 2 0 Coat F domain IKI3 PF04762.12 CCD27111.1 - 0 1156.6 7.7 0 1155.9 7.7 1.3 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 CCD27111.1 - 0.002 18.4 1.5 1.4 9.3 0.5 3.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Phytochelatin_C PF09328.10 CCD27111.1 - 0.13 11.6 1.4 9.1 5.5 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1984) ERp29 PF07749.12 CCD27111.1 - 7.5 7.5 6.6 66 4.5 0.2 2.9 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain SWC7 PF17330.2 CCD27112.1 - 6.7e-35 119.1 0.5 9.2e-35 118.6 0.5 1.2 1 0 0 1 1 1 1 SWR1 chromatin-remodelling complex, sub-unit Swc7 Vac14_Fig4_bd PF11916.8 CCD27113.1 - 3e-66 222.5 7.1 3.4e-66 222.3 5.0 2.1 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CCD27113.1 - 4.9e-47 158.5 0.1 1.2e-37 128.4 0.0 4.6 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CCD27113.1 - 1e-08 35.5 0.4 0.32 11.5 0.0 6.2 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.22 CCD27113.1 - 1.2e-08 34.5 5.3 0.0014 18.7 0.0 6.8 8 0 0 8 8 7 1 HEAT repeat CLASP_N PF12348.8 CCD27113.1 - 7.8e-06 25.6 0.4 0.89 9.1 0.4 4.7 4 1 0 4 4 4 1 CLASP N terminal RIX1 PF08167.12 CCD27113.1 - 0.021 14.6 1.4 1.7 8.3 0.1 3.6 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis AbiJ_NTD5 PF18865.1 CCD27113.1 - 0.037 13.8 1.0 1.5 8.7 0.1 3.6 3 0 0 3 3 3 0 AbiJ N-terminal domain 5 Secretin_N_2 PF07655.13 CCD27113.1 - 0.1 13.2 6.8 0.3 11.7 6.8 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain ComC PF03047.14 CCD27113.1 - 0.24 11.2 0.8 0.65 9.8 0.8 1.7 1 0 0 1 1 1 0 COMC family Dopey_N PF04118.14 CCD27113.1 - 0.31 10.1 19.9 0.066 12.3 0.8 4.8 3 2 2 5 5 5 0 Dopey, N-terminal Arm PF00514.23 CCD27113.1 - 0.42 10.7 5.7 7.1 6.8 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 CCD27113.1 - 0.75 9.8 13.5 6 6.9 0.2 5.0 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HSP70 PF00012.20 CCD27113.1 - 5.2 5.1 9.0 7.9 4.5 9.0 1.2 1 0 0 1 1 1 0 Hsp70 protein zf-C2H2_2 PF12756.7 CCD27114.1 - 5.8e-29 100.4 7.0 1e-27 96.4 1.1 2.6 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 CCD27114.1 - 0.012 14.9 0.0 0.38 9.9 0.0 2.6 2 1 0 2 2 2 0 Putative actin-like family zf-met PF12874.7 CCD27114.1 - 5.2 7.6 6.1 37 4.9 0.3 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type RIBIOP_C PF04950.12 CCD27115.1 - 5.9e-105 350.9 0.1 1.4e-104 349.6 0.1 1.7 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CCD27115.1 - 1.3e-21 76.5 0.0 4.2e-21 74.8 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain NAD_binding_10 PF13460.6 CCD27115.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Peptidase_M16_M PF16187.5 CCD27116.1 - 2.9e-86 289.2 5.3 2.9e-86 289.2 5.3 1.9 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CCD27116.1 - 1.2e-37 129.2 0.0 1.4e-36 125.7 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CCD27116.1 - 3.3e-31 108.7 8.5 5.2e-20 72.2 0.1 3.4 4 0 0 4 4 4 2 Peptidase M16 inactive domain UBA_3 PF09288.10 CCD27117.1 - 0.06 13.2 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Slx4 PF09494.10 CCD27117.1 - 0.088 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Slx4 endonuclease CFEM PF05730.11 CCD27118.1 - 6.9e-08 32.5 14.6 1.9e-07 31.1 14.6 1.8 1 0 0 1 1 1 1 CFEM domain Utp14 PF04615.13 CCD27118.1 - 3.7 6.0 12.0 4.2 5.8 12.0 1.0 1 0 0 1 1 1 0 Utp14 protein Arrestin_N PF00339.29 CCD27119.1 - 3e-06 27.3 0.1 7e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain ATP-synt_10 PF05176.14 CCD27120.1 - 1.4e-92 309.6 1.8 1.5e-92 309.4 1.8 1.0 1 0 0 1 1 1 1 ATP10 protein Ig_4 PF16680.5 CCD27120.1 - 0.062 13.6 0.1 0.18 12.1 0.1 1.8 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain zf-RING_5 PF14634.6 CCD27121.1 - 1.5e-07 31.3 6.5 3.8e-07 30.0 6.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CCD27121.1 - 0.047 13.6 7.3 0.16 11.9 7.4 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CCD27121.1 - 0.3 11.0 2.1 0.64 9.9 2.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 CCD27121.1 - 0.64 9.9 7.1 1.4 8.8 7.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCD27121.1 - 1.8 8.9 12.7 0.084 13.2 6.8 1.8 2 0 0 2 2 2 0 Ring finger domain COX7C PF02935.16 CCD27122.1 - 8.3e-24 83.6 3.8 9.4e-24 83.5 3.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc LapA_dom PF06305.11 CCD27122.1 - 0.09 12.6 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Sec1 PF00995.23 CCD27123.1 - 1.5e-88 298.5 12.0 1.7e-88 298.3 12.0 1.0 1 0 0 1 1 1 1 Sec1 family Dehydratase_SU PF02287.15 CCD27123.1 - 0.044 13.9 0.0 0.32 11.1 0.0 2.2 2 0 0 2 2 2 0 Dehydratase small subunit AAA PF00004.29 CCD27124.1 - 1.1e-89 297.7 0.0 1.9e-43 148.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCD27124.1 - 1.7e-27 94.9 0.4 2.4e-12 46.4 0.2 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CCD27124.1 - 5.6e-13 48.9 0.0 1.9e-05 24.4 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCD27124.1 - 1e-12 48.8 0.4 1.6e-06 28.6 0.0 3.5 2 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 CCD27124.1 - 8.6e-12 45.2 0.1 4e-05 23.6 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCD27124.1 - 4.4e-09 36.7 1.1 0.00038 20.7 0.1 4.3 2 2 1 3 3 3 1 AAA domain AAA_2 PF07724.14 CCD27124.1 - 1.7e-07 31.5 0.0 0.015 15.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CCD27124.1 - 2.7e-07 30.8 0.0 0.0028 17.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CCD27124.1 - 4.3e-07 30.0 0.0 0.0016 18.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CCD27124.1 - 6.4e-07 28.9 0.0 0.0065 15.7 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain Rad17 PF03215.15 CCD27124.1 - 8.1e-06 25.9 0.0 0.012 15.6 0.0 3.0 2 1 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 CCD27124.1 - 1.2e-05 25.6 0.0 0.14 12.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Bac_DnaA PF00308.18 CCD27124.1 - 1.5e-05 25.0 0.0 0.0022 17.9 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein Mg_chelatase PF01078.21 CCD27124.1 - 2.7e-05 23.7 0.4 0.075 12.4 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CCD27124.1 - 0.00014 22.2 0.0 0.78 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CCD27124.1 - 0.00021 21.3 0.1 0.2 11.7 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 CCD27124.1 - 0.00022 20.9 5.6 1.1 8.7 0.0 4.2 2 2 1 3 3 3 2 AAA domain AAA_7 PF12775.7 CCD27124.1 - 0.00028 20.4 0.1 0.49 9.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region CDC48_N PF02359.18 CCD27124.1 - 0.00049 20.2 0.2 0.0017 18.5 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_11 PF13086.6 CCD27124.1 - 0.00063 19.6 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CCD27124.1 - 0.0012 18.8 0.5 0.032 14.2 0.0 3.1 4 0 0 4 4 4 1 NACHT domain IstB_IS21 PF01695.17 CCD27124.1 - 0.0016 18.2 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 CCD27124.1 - 0.0021 18.2 0.0 0.36 10.9 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 CCD27124.1 - 0.0025 17.7 0.0 2.4 8.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCD27124.1 - 0.0058 16.3 0.2 13 5.5 0.0 4.5 3 2 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.6 CCD27124.1 - 0.009 15.8 0.0 0.54 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CCD27124.1 - 0.0093 15.7 0.0 0.062 13.0 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CCD27124.1 - 0.013 15.2 0.8 0.072 12.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 CCD27124.1 - 0.014 14.7 0.4 12 5.2 0.1 3.2 2 1 1 3 3 3 0 KaiC AAA_18 PF13238.6 CCD27124.1 - 0.017 15.7 0.0 1.8 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CCD27124.1 - 0.02 15.4 0.1 0.68 10.5 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Vps4_C PF09336.10 CCD27124.1 - 0.027 14.5 0.0 4.7 7.3 0.0 3.1 3 0 0 3 3 2 0 Vps4 C terminal oligomerisation domain AAA_19 PF13245.6 CCD27124.1 - 0.049 14.0 1.8 0.43 10.9 0.1 2.8 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 CCD27124.1 - 0.051 12.7 0.0 1.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AFG1_ATPase PF03969.16 CCD27124.1 - 0.055 12.3 0.0 0.15 10.9 0.0 1.6 1 0 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 CCD27124.1 - 0.077 12.3 0.1 9.2 5.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin DSHCT PF08148.12 CCD27125.1 - 2.2e-47 160.8 2.0 6e-47 159.3 0.1 2.5 3 0 0 3 3 3 1 DSHCT (NUC185) domain Ski2_N PF17911.1 CCD27125.1 - 2.3e-37 127.8 0.1 9.5e-37 125.8 0.1 2.0 2 0 0 2 2 2 1 Ski2 N-terminal region DEAD PF00270.29 CCD27125.1 - 4.1e-21 75.5 0.2 1.8e-20 73.5 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 CCD27125.1 - 9.3e-14 52.0 9.6 2e-13 50.9 9.6 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 CCD27125.1 - 5e-07 30.0 0.0 3.7e-06 27.2 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD27125.1 - 1.1e-06 28.7 1.8 1.8e-06 28.1 0.1 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DNA_topoisoIV PF00521.20 CCD27125.1 - 0.57 9.0 9.9 0.26 10.1 6.6 2.2 2 1 0 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A HD_assoc PF13286.6 CCD27125.1 - 0.81 10.3 2.6 0.94 10.1 0.1 2.5 3 0 0 3 3 3 0 Phosphohydrolase-associated domain Bromodomain PF00439.25 CCD27126.1 - 1.9e-37 127.2 6.4 1.1e-18 67.1 0.1 2.9 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 CCD27126.1 - 2.3e-21 75.7 1.5 8.1e-21 74.0 1.5 2.0 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF4094 PF13334.6 CCD27126.1 - 0.044 14.2 0.4 0.044 14.2 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) Dus PF01207.17 CCD27127.1 - 8.2e-41 140.1 0.0 2.5e-30 105.6 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 CCD27127.1 - 9.3e-07 28.5 5.6 0.00015 21.5 0.3 2.7 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 CCD27127.1 - 0.0013 18.6 4.8 0.019 14.9 0.3 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CCD27127.1 - 0.0095 16.0 0.9 0.0095 16.0 0.9 2.5 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 CCD27127.1 - 0.18 12.5 3.7 3 8.6 0.2 3.0 1 1 1 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 CCD27127.1 - 0.31 11.6 6.7 0.13 12.8 0.5 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-C2H2_4 PF13894.6 CCD27128.1 - 0.00015 22.3 15.6 0.15 12.9 0.8 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CCD27128.1 - 0.0016 18.8 18.4 0.018 15.4 1.3 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCD27128.1 - 0.011 16.1 14.5 0.11 12.9 0.8 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_aberr PF17017.5 CCD27128.1 - 0.011 15.9 1.5 0.011 15.9 1.5 4.2 3 2 1 4 4 4 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 CCD27128.1 - 0.12 12.7 5.4 3.4 8.1 1.4 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CCD27128.1 - 8.5 6.5 18.6 1.6 8.8 3.0 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Dus PF01207.17 CCD27130.1 - 2.1e-75 253.7 0.0 2.6e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF4050 PF13259.6 CCD27131.1 - 1.9e-10 41.4 0.2 1.9e-10 41.4 0.2 3.5 1 1 2 3 3 3 2 Protein of unknown function (DUF4050) FAM219A PF15260.6 CCD27131.1 - 0.069 13.5 1.3 0.21 12.0 0.6 2.0 1 1 1 2 2 2 0 Protein family FAM219A Luteo_coat PF00894.18 CCD27131.1 - 0.14 12.1 1.6 0.24 11.3 1.6 1.3 1 0 0 1 1 1 0 Luteovirus coat protein Imm5 PF14423.6 CCD27131.1 - 0.59 10.3 4.0 1.1 9.4 0.0 2.3 2 1 0 2 2 2 0 Immunity protein Imm5 AbbA_antirepres PF14156.6 CCD27132.1 - 0.0018 18.1 1.3 0.0078 16.1 1.3 1.9 1 1 1 2 2 2 1 Antirepressor AbbA Utp21 PF04192.12 CCD27133.1 - 7.4e-76 254.7 1.5 1.1e-75 254.1 1.5 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 CCD27133.1 - 2.9e-18 66.0 0.0 1.1e-05 25.6 0.0 5.8 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCD27133.1 - 4.3e-15 55.8 13.5 4.6e-08 33.6 0.8 8.4 8 0 0 8 8 8 1 WD domain, G-beta repeat WD40_like PF17005.5 CCD27133.1 - 7.4e-07 28.8 4.3 0.15 11.4 0.0 3.6 2 1 0 3 3 3 3 WD40-like domain PQQ_2 PF13360.6 CCD27133.1 - 7.6e-05 22.4 0.0 0.01 15.4 0.0 2.7 3 0 0 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.16 CCD27133.1 - 0.0044 15.6 0.0 0.028 13.0 0.0 2.0 2 0 0 2 2 2 1 Cytochrome D1 heme domain PQQ_3 PF13570.6 CCD27133.1 - 0.005 17.3 0.6 0.15 12.6 0.0 3.5 4 0 0 4 4 4 1 PQQ-like domain CPSF_A PF03178.15 CCD27133.1 - 0.0074 15.6 0.2 0.15 11.3 0.1 2.7 3 0 0 3 3 3 1 CPSF A subunit region LVIVD PF08309.11 CCD27133.1 - 0.019 14.2 0.2 3.8 6.9 0.0 2.5 2 0 0 2 2 2 0 LVIVD repeat Nucleoporin_N PF08801.11 CCD27133.1 - 0.08 11.7 0.6 4.1 6.0 0.0 2.8 2 1 1 3 3 3 0 Nup133 N terminal like His_Phos_2 PF00328.22 CCD27134.1 - 1.1e-138 462.7 0.5 1.8e-138 462.1 0.5 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CCD27134.1 - 1e-38 131.4 0.1 2.9e-38 129.9 0.1 1.8 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CCD27134.1 - 9.3e-08 31.9 0.2 2.9e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 CCD27134.1 - 0.0043 17.1 0.2 0.022 14.8 0.2 2.3 1 1 0 1 1 1 1 ATP-grasp domain DUF87 PF01935.17 CCD27134.1 - 0.048 13.7 1.4 0.23 11.5 0.2 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain Ctr PF04145.15 CCD27135.1 - 8.5e-36 123.8 0.7 1.3e-35 123.2 0.7 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Hid1 PF12722.7 CCD27136.1 - 2.4e-35 122.0 89.3 3.5e-24 85.0 13.8 6.0 3 2 1 5 5 5 4 High-temperature-induced dauer-formation protein WGG PF10273.9 CCD27137.1 - 9.5e-29 99.9 0.2 2.4e-28 98.6 0.2 1.7 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Recombinase PF07508.13 CCD27137.1 - 0.065 13.6 0.4 0.27 11.6 0.4 2.1 1 1 0 1 1 1 0 Recombinase Metallophos PF00149.28 CCD27138.1 - 3.9e-34 119.0 0.5 7.1e-34 118.1 0.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Caps_synth_GfcC PF06251.11 CCD27139.1 - 0.09 12.4 7.0 0.059 13.0 3.9 2.1 2 0 0 2 2 2 0 Capsule biosynthesis GfcC GP70 PF17429.2 CCD27139.1 - 0.099 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Gene product 70 SEN1_N PF12726.7 CCD27140.1 - 4.9e-212 706.2 22.1 7.1e-212 705.7 22.1 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 CCD27140.1 - 1.5e-71 241.2 0.7 1.5e-71 241.2 0.7 3.7 3 2 0 3 3 3 1 AAA domain AAA_12 PF13087.6 CCD27140.1 - 3.3e-64 216.2 0.1 9.7e-64 214.7 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCD27140.1 - 4.8e-10 39.5 0.0 9.3e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CCD27140.1 - 8.9e-09 35.8 0.0 7.2e-08 32.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CCD27140.1 - 3.1e-05 23.7 0.6 3.1e-05 23.7 0.6 5.2 3 2 0 3 3 3 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 CCD27140.1 - 0.00081 19.2 0.1 0.5 10.1 0.0 3.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF1899 PF08953.11 CCD27141.1 - 4.8e-32 109.6 0.8 1.1e-31 108.5 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 CCD27141.1 - 6.1e-22 77.2 0.4 1.3e-21 76.2 0.4 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CCD27141.1 - 3.7e-16 59.2 7.5 0.00011 22.9 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 CCD27141.1 - 3.2e-08 32.7 0.1 7.2e-05 21.6 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CCD27141.1 - 4.3e-05 23.7 0.1 0.021 15.1 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCD27141.1 - 0.00093 19.1 0.4 1.9 8.3 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CCD27141.1 - 0.0054 15.7 0.0 0.21 10.5 0.0 2.4 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cortex-I_coil PF09304.10 CCD27141.1 - 0.0074 16.5 1.8 0.0074 16.5 1.8 2.0 2 0 0 2 2 2 1 Cortexillin I, coiled coil DUF5046 PF16465.5 CCD27141.1 - 0.038 13.4 0.0 0.35 10.3 0.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF5046) SlyX PF04102.12 CCD27141.1 - 0.42 11.3 2.6 0.94 10.1 2.6 1.6 1 0 0 1 1 1 0 SlyX zf-C3HC4 PF00097.25 CCD27142.1 - 2.6e-07 30.4 3.1 7.5e-07 28.9 3.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCD27142.1 - 1.2e-06 28.5 6.4 2.9e-06 27.2 6.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CCD27142.1 - 1.6e-06 28.3 6.0 3.4e-06 27.3 6.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CCD27142.1 - 1.8e-05 24.6 6.1 6.9e-05 22.7 6.2 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CCD27142.1 - 0.00014 21.7 6.4 0.00057 19.7 6.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCD27142.1 - 0.00065 19.5 3.5 0.00065 19.5 3.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCD27142.1 - 0.0025 17.9 6.7 0.012 15.8 6.9 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CCD27142.1 - 0.052 13.4 10.5 5.2 7.0 7.4 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 FYVE PF01363.21 CCD27142.1 - 0.22 11.7 2.3 0.63 10.2 2.3 1.8 1 0 0 1 1 1 0 FYVE zinc finger zf-Nse PF11789.8 CCD27142.1 - 0.41 10.5 4.6 1.1 9.1 4.6 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit IBR PF01485.21 CCD27142.1 - 1.2 9.4 3.9 23 5.3 0.1 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_10 PF16685.5 CCD27142.1 - 1.7 8.8 5.8 1.2 9.3 3.2 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 adh_short PF00106.25 CCD27143.1 - 1.8e-28 99.3 0.0 3.2e-28 98.5 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCD27143.1 - 4.8e-16 59.0 0.0 6.6e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UEV PF05743.13 CCD27143.1 - 0.015 15.2 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 UEV domain KR PF08659.10 CCD27143.1 - 0.017 15.0 0.1 0.89 9.4 0.0 2.1 2 0 0 2 2 2 0 KR domain PfaD_N PF18328.1 CCD27143.1 - 0.02 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Fatty acid synthase subunit PfaD N-terminal domain CNH PF00780.22 CCD27144.1 - 1.5e-17 64.1 3.0 1.5e-17 64.1 3.0 2.2 2 1 0 2 2 2 1 CNH domain RhoGEF PF00621.20 CCD27144.1 - 2.5e-06 27.9 0.2 1.1e-05 25.7 0.2 2.2 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 CCD27144.1 - 4.4e-05 23.6 3.3 4.4e-05 23.6 3.3 3.9 3 1 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 CCD27144.1 - 0.011 16.2 0.1 0.011 16.2 0.1 4.0 5 0 0 5 5 5 0 PH domain Ribosomal_S4e PF00900.20 CCD27144.1 - 0.083 12.8 0.5 0.32 10.9 0.5 2.0 1 0 0 1 1 1 0 Ribosomal family S4e CHCH PF06747.13 CCD27145.1 - 2.7e-07 30.6 3.5 5.8e-07 29.5 3.5 1.6 1 0 0 1 1 1 1 CHCH domain SARAF PF06682.12 CCD27145.1 - 0.0016 18.1 3.5 0.0016 18.1 3.5 2.2 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis Gram_pos_anchor PF00746.21 CCD27145.1 - 0.0093 15.9 1.7 0.011 15.7 0.3 1.9 2 0 0 2 2 2 1 LPXTG cell wall anchor motif GCK PF07802.11 CCD27145.1 - 1.1 9.7 11.0 0.039 14.4 3.3 2.5 2 0 0 2 2 2 0 GCK domain G-patch PF01585.23 CCD27146.1 - 1.6e-12 47.1 3.0 2.9e-12 46.3 3.0 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CCD27146.1 - 0.00023 21.2 0.8 0.00054 20.0 0.8 1.6 1 0 0 1 1 1 1 G-patch domain ApoC-I PF04691.12 CCD27146.1 - 0.056 13.4 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) APG6_N PF17675.1 CCD27146.1 - 0.66 10.5 7.0 0.23 12.0 3.4 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region NPV_P10 PF05531.12 CCD27146.1 - 6.9 7.2 7.8 7.8 7.0 3.9 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein APG17 PF04108.12 CCD27147.1 - 3.8e-100 335.8 23.4 4.3e-100 335.6 23.4 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 HBM PF16591.5 CCD27147.1 - 0.11 11.9 3.0 0.35 10.2 0.0 2.7 2 1 0 2 2 2 0 Helical bimodular sensor domain FTO_CTD PF12934.7 CCD27147.1 - 0.39 10.5 5.1 0.49 10.1 0.2 2.9 3 0 0 3 3 3 0 FTO C-terminal domain NOG1_N PF17835.1 CCD27147.1 - 3 7.8 11.5 2.4 8.1 1.3 3.4 2 2 0 3 3 3 0 NOG1 N-terminal helical domain Myb_DNA-bind_5 PF13873.6 CCD27147.1 - 9.2 6.4 8.7 1.1 9.4 0.1 3.6 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain PP-binding PF00550.25 CCD27148.1 - 9e-12 45.2 0.2 1.4e-11 44.5 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CCD27148.1 - 6.4e-08 32.7 0.7 9.7e-08 32.1 0.7 1.4 1 0 0 1 1 1 1 Acyl-carrier DHR-2 PF06920.13 CCD27149.1 - 2.4e-35 122.2 6.0 2.4e-35 122.2 6.0 1.9 2 0 0 2 2 2 1 Dock homology region 2 Seryl_tRNA_N PF02403.22 CCD27149.1 - 0.03 14.5 1.2 0.058 13.6 0.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SRP1_TIP1 PF00660.17 CCD27150.1 - 2.3e-34 117.4 0.2 2.8e-34 117.1 0.2 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family Plk4_PB1 PF18190.1 CCD27151.1 - 2.2 8.5 5.7 22 5.3 0.1 3.3 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 1 Fz PF01392.22 CCD27151.1 - 4.5 7.9 12.1 20 5.9 3.7 2.8 1 1 2 3 3 3 0 Fz domain Proteasom_Rpn13 PF04683.13 CCD27152.1 - 5e-22 78.3 0.1 7.7e-22 77.6 0.1 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Amidohydro_2 PF04909.14 CCD27153.1 - 1.3e-05 25.1 0.0 3.6e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase DUF3627 PF12299.8 CCD27153.1 - 0.033 14.3 0.2 0.075 13.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) OB_NTP_bind PF07717.16 CCD27154.1 - 3e-15 56.4 0.0 9.5e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CCD27154.1 - 2.5e-14 53.5 0.2 1.1e-13 51.5 0.2 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 CCD27154.1 - 2.2e-13 50.5 2.5 2.2e-13 50.5 2.5 2.5 2 0 0 2 2 2 1 RWD domain DEAD PF00270.29 CCD27154.1 - 6.2e-10 39.1 0.3 2.4e-09 37.2 0.3 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ATPase PF06745.13 CCD27154.1 - 6.7e-05 22.3 0.2 0.01 15.2 0.0 2.6 2 0 0 2 2 2 1 KaiC AAA_19 PF13245.6 CCD27154.1 - 0.00015 22.1 0.1 0.00037 20.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCD27154.1 - 0.00064 20.0 0.8 0.0036 17.6 0.3 2.6 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 CCD27154.1 - 0.0011 18.9 0.1 0.0034 17.3 0.1 1.8 1 0 0 1 1 1 1 NACHT domain T2SSE PF00437.20 CCD27154.1 - 0.0036 16.4 0.0 0.0088 15.1 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 CCD27154.1 - 0.0049 16.6 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CCD27154.1 - 0.015 15.8 0.3 0.015 15.8 0.3 5.1 2 1 1 3 3 2 0 AAA domain ResIII PF04851.15 CCD27154.1 - 0.024 14.6 0.0 0.024 14.6 0.0 3.5 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit PhoH PF02562.16 CCD27154.1 - 0.032 13.7 0.1 0.11 11.9 0.0 1.9 2 1 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 CCD27154.1 - 0.058 13.8 0.0 0.2 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 CCD27154.1 - 0.06 12.9 0.0 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 CCD27154.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain dsRBD2 PF17842.1 CCD27154.1 - 2 8.6 8.0 2.7 8.2 0.0 3.1 3 0 0 3 3 3 0 Double-stranded RNA binding domain 2 CDC73_C PF05179.14 CCD27155.1 - 2.5e-55 186.4 4.3 4.7e-55 185.6 4.3 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal DUF2220 PF09983.9 CCD27155.1 - 0.099 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) Vps36_ESCRT-II PF11605.8 CCD27156.1 - 1.9e-31 108.1 0.4 1.9e-31 108.1 0.4 2.3 3 0 0 3 3 3 1 Vacuolar protein sorting protein 36 Vps36 EAP30 PF04157.16 CCD27156.1 - 7.4e-20 71.2 0.0 1.3e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 CCD27156.1 - 2.2e-13 49.4 5.7 2.2e-13 49.4 5.7 3.6 2 1 2 4 4 4 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain GRAM PF02893.20 CCD27156.1 - 0.00045 20.1 0.4 0.0021 17.9 0.0 2.3 2 0 0 2 2 2 1 GRAM domain PH_TFIIH PF08567.11 CCD27156.1 - 0.00096 19.4 0.6 0.0045 17.3 0.0 2.4 2 1 1 3 3 3 1 TFIIH p62 subunit, N-terminal domain DZR PF12773.7 CCD27156.1 - 0.0045 17.0 3.9 0.038 14.0 0.4 2.3 1 1 1 2 2 2 2 Double zinc ribbon bPH_3 PF14470.6 CCD27156.1 - 0.014 15.7 0.5 0.06 13.7 0.5 2.1 1 0 0 1 1 1 0 Bacterial PH domain zf-RING_7 PF02591.15 CCD27156.1 - 0.016 15.4 1.5 1.2 9.4 0.3 2.9 2 0 0 2 2 2 0 C4-type zinc ribbon domain Tnp_22_trimer PF17489.2 CCD27156.1 - 0.026 14.5 1.3 0.095 12.7 1.3 2.0 1 0 0 1 1 1 0 L1 transposable element trimerization domain zf-Sec23_Sec24 PF04810.15 CCD27156.1 - 0.056 13.5 12.0 0.33 11.0 0.2 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Lar_restr_allev PF14354.6 CCD27156.1 - 0.5 10.8 3.1 0.26 11.7 0.4 1.9 2 1 0 2 2 1 0 Restriction alleviation protein Lar zf-RanBP PF00641.18 CCD27156.1 - 3.7 6.9 8.3 3.8 6.9 0.2 3.2 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others SUR7 PF06687.12 CCD27157.1 - 8.6e-40 136.6 22.6 1.1e-39 136.3 22.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family SUR7 PF06687.12 CCD27158.1 - 2.5e-08 33.8 25.3 1.1e-06 28.5 25.3 2.9 1 1 0 1 1 1 1 SUR7/PalI family HisK_sensor PF18698.1 CCD27158.1 - 0.11 12.9 2.5 0.24 11.8 2.5 1.6 1 0 0 1 1 1 0 Histidine kinase sensor domain MCPsignal PF00015.21 CCD27158.1 - 1.5 8.6 13.5 0.038 13.8 4.3 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain I_LWEQ PF01608.17 CCD27158.1 - 7.5 6.8 13.6 0.26 11.5 1.4 2.9 2 1 1 3 3 3 0 I/LWEQ domain DUF1729 PF08354.10 CCD27159.1 - 9.4e-158 524.7 0.0 1.5e-157 524.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 CCD27159.1 - 9.2e-107 357.2 0.0 1.5e-105 353.2 0.0 2.8 3 0 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 CCD27159.1 - 1.9e-44 151.0 0.1 5.9e-44 149.4 0.1 1.9 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 CCD27159.1 - 4.3e-36 124.8 0.0 1.1e-35 123.5 0.0 1.7 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 CCD27159.1 - 3e-35 120.4 0.0 5.9e-35 119.5 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 CCD27159.1 - 4e-34 117.4 0.4 1e-33 116.1 0.4 1.7 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 CCD27159.1 - 2.2e-17 63.4 0.0 7.3e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase TPPII_N PF12583.8 CCD27159.1 - 0.082 13.5 0.2 0.2 12.2 0.2 1.6 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal SRR1 PF07985.12 CCD27160.1 - 5.6e-17 61.5 0.1 9.9e-17 60.7 0.1 1.4 1 0 0 1 1 1 1 SRR1 RNR_inhib PF08591.10 CCD27161.1 - 0.00021 22.6 0.6 0.00047 21.4 0.1 2.1 2 1 0 2 2 2 1 Ribonucleotide reductase inhibitor Engrail_1_C_sig PF10525.9 CCD27161.1 - 0.095 11.9 0.9 0.24 10.7 0.9 1.7 1 0 0 1 1 1 0 Engrailed homeobox C-terminal signature domain Aminotran_3 PF00202.21 CCD27162.1 - 3.1e-124 414.7 0.0 3.5e-124 414.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CCD27162.1 - 0.0026 17.1 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase OAM_dimer PF16554.5 CCD27162.1 - 0.019 15.4 0.0 0.22 12.0 0.0 2.4 3 0 0 3 3 3 0 Dimerisation domain of d-ornithine 4,5-aminomutase LSM PF01423.22 CCD27163.1 - 1.7e-19 69.2 0.2 2e-19 69.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CCD27163.1 - 0.013 15.6 0.0 0.064 13.4 0.0 1.9 2 0 0 2 2 2 0 RimP C-terminal SH3 domain Imm65 PF15582.6 CCD27163.1 - 0.027 13.3 0.0 0.03 13.2 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 65 Fe_dep_repress PF01325.19 CCD27163.1 - 0.039 14.1 0.0 0.083 13.1 0.0 1.5 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain MRP-L47 PF06984.13 CCD27164.1 - 1.6e-18 66.6 1.7 4.4e-18 65.2 1.7 1.8 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Gemini_AL1 PF00799.20 CCD27164.1 - 0.076 13.4 0.2 0.076 13.4 0.2 3.3 3 1 1 4 4 4 0 Geminivirus Rep catalytic domain zf-ZPR1 PF03367.13 CCD27164.1 - 0.15 11.9 2.1 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 ZPR1 zinc-finger domain COPIIcoated_ERV PF07970.12 CCD27164.1 - 0.19 11.6 2.8 0.13 12.1 0.6 1.8 2 0 0 2 2 2 0 Endoplasmic reticulum vesicle transporter Ribosomal_S3Ae PF01015.18 CCD27165.1 - 3.6e-87 291.2 5.3 4.3e-87 290.9 5.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 CCD27165.1 - 0.034 13.7 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region HIGH_NTase1_ass PF16581.5 CCD27165.1 - 0.045 13.8 0.2 0.061 13.3 0.2 1.2 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region AAA_lid_10 PF17872.1 CCD27166.1 - 7.4e-18 64.5 0.3 3.1e-17 62.5 0.3 2.2 1 0 0 1 1 1 1 AAA lid domain BAH PF01426.18 CCD27166.1 - 9.5e-18 64.2 0.4 3.8e-17 62.3 0.4 2.1 1 0 0 1 1 1 1 BAH domain AAA PF00004.29 CCD27166.1 - 1e-09 38.9 0.0 3.5e-09 37.2 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Spidroin_N PF16763.5 CCD27166.1 - 0.002 18.2 1.5 0.0032 17.5 0.2 2.0 2 0 0 2 2 2 1 Major ampullate spidroin 1, spider silk protein 1, N-term AAA_22 PF13401.6 CCD27166.1 - 0.0022 18.3 0.0 0.01 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Ins_allergen_rp PF06757.13 CCD27166.1 - 0.0025 17.8 0.2 0.015 15.3 0.2 2.1 2 0 0 2 2 2 1 Insect allergen related repeat, nitrile-specifier detoxification AAA_16 PF13191.6 CCD27166.1 - 0.0048 17.3 0.0 0.11 12.8 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain Ribosomal_TL5_C PF14693.6 CCD27166.1 - 0.055 13.8 0.0 0.58 10.5 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein TL5, C-terminal domain SUR7 PF06687.12 CCD27167.1 - 1.4e-06 28.1 11.3 2e-06 27.6 11.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family COPIIcoated_ERV PF07970.12 CCD27168.1 - 7e-22 78.4 0.0 1.3e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CCD27168.1 - 1.9e-21 76.2 0.1 4.8e-21 74.9 0.1 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) GCIP PF13324.6 CCD27170.1 - 0.0032 17.1 0.1 0.0052 16.4 0.1 1.4 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting LHH PF14411.6 CCD27170.1 - 0.18 12.0 0.2 0.18 12.0 0.2 2.9 3 1 0 3 3 3 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Hexokinase_2 PF03727.16 CCD27171.1 - 1.3e-22 80.5 0.0 2.3e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CCD27171.1 - 3.7e-17 62.9 0.0 7e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Hexokinase T3SS_needle_F PF09392.10 CCD27171.1 - 0.063 13.5 1.0 0.17 12.1 0.3 2.0 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF vATP-synt_AC39 PF01992.16 CCD27172.1 - 3.4e-106 355.5 2.0 3.8e-106 355.4 2.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit PPV_E2_C PF00511.17 CCD27172.1 - 0.15 12.2 0.8 0.52 10.5 0.5 2.0 2 0 0 2 2 2 0 E2 (early) protein, C terminal SF3A3 PF16837.5 CCD27172.1 - 0.21 12.1 1.6 23 5.6 0.0 3.1 2 1 1 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Ribosomal_L6e PF01159.19 CCD27173.1 - 3.8e-38 130.4 4.1 5.4e-38 130.0 4.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e Type_III_YscX PF09474.10 CCD27173.1 - 0.093 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) Piwi PF02171.17 CCD27174.1 - 1.3e-68 231.5 0.4 2.2e-68 230.7 0.1 1.6 2 0 0 2 2 2 1 Piwi domain AGO_N PF18236.1 CCD27174.1 - 1.1e-60 203.2 0.0 1.1e-60 203.2 0.0 2.7 3 0 0 3 3 3 1 Argonaute N domain Ago_N_1 PF18351.1 CCD27174.1 - 1.1e-46 157.2 0.1 1.1e-46 157.2 0.1 3.4 4 0 0 4 4 4 1 Fungal Argonaute N-terminal domain ArgoN PF16486.5 CCD27174.1 - 0.0039 17.8 0.1 0.02 15.5 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of argonaute PAZ PF02170.22 CCD27174.1 - 0.04 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 PAZ domain FKBP_C PF00254.28 CCD27175.1 - 2.6e-29 101.4 0.1 3.9e-28 97.6 0.0 2.5 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 CCD27175.1 - 3.3e-20 72.6 0.1 3.3e-20 72.6 0.1 2.7 2 1 0 2 2 2 1 Nucleoplasmin-like domain TFR_dimer PF04253.15 CCD27176.1 - 2.9e-14 53.2 0.0 6.3e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CCD27176.1 - 3.3e-11 43.3 0.0 5.5e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CCD27176.1 - 5.9e-08 32.6 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-H2C2_2 PF13465.6 CCD27177.1 - 6.7e-07 29.5 10.1 8.1e-06 26.0 4.5 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 CCD27177.1 - 0.00016 21.9 11.0 0.0041 17.5 2.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD27177.1 - 0.0016 19.1 10.7 0.07 14.0 1.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger Methyltransf_16 PF10294.9 CCD27178.1 - 1.7e-23 83.3 0.2 3e-23 82.4 0.2 1.4 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 CCD27178.1 - 0.023 14.2 0.0 0.081 12.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Glyco_hydro_47 PF01532.20 CCD27179.1 - 2.6e-137 458.4 0.3 3.2e-137 458.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 IBN_N PF03810.19 CCD27180.1 - 1.7e-16 59.9 6.8 2.2e-16 59.5 1.1 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain Phage_tail_U PF06141.11 CCD27180.1 - 0.1 13.0 2.5 0.5 10.7 0.0 3.0 3 0 0 3 3 3 0 Phage minor tail protein U Utp12 PF04003.12 CCD27181.1 - 8e-07 29.3 2.6 1.3e-06 28.6 2.6 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Pribosyltran PF00156.27 CCD27182.1 - 1.7e-11 43.9 0.1 2.4e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NOT2_3_5 PF04153.18 CCD27182.1 - 0.094 12.8 0.0 0.7 10.0 0.0 2.0 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family Sec39 PF08314.11 CCD27183.1 - 5.4e-115 385.6 19.7 1.4e-114 384.2 19.7 1.6 1 1 0 1 1 1 1 Secretory pathway protein Sec39 DUF1137 PF06587.11 CCD27183.1 - 0.0054 16.7 0.5 0.043 13.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1137) TMF_TATA_bd PF12325.8 CCD27184.1 - 1.8e-34 118.4 75.6 6.8e-34 116.5 16.0 5.7 3 1 2 5 5 5 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 CCD27184.1 - 4.2e-14 52.3 14.0 4.2e-14 52.3 14.0 9.1 4 2 6 10 10 9 2 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 CCD27184.1 - 7.4e-05 21.8 80.6 0.092 11.6 15.4 4.4 2 1 2 4 4 4 4 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 CCD27184.1 - 9.1e-05 22.6 5.2 9.1e-05 22.6 5.2 6.5 2 2 2 5 5 5 1 Seryl-tRNA synthetase N-terminal domain Lebercilin PF15619.6 CCD27184.1 - 9.6e-05 22.1 86.0 0.00012 21.9 14.5 4.2 3 1 2 5 5 3 2 Ciliary protein causing Leber congenital amaurosis disease TPR_MLP1_2 PF07926.12 CCD27184.1 - 0.00014 21.9 79.1 0.00059 19.9 12.7 6.0 2 2 3 5 5 5 3 TPR/MLP1/MLP2-like protein HOOK PF05622.12 CCD27184.1 - 0.00021 19.6 75.1 0.0019 16.5 8.1 4.2 2 1 2 4 4 4 2 HOOK protein DUF3584 PF12128.8 CCD27184.1 - 0.001 16.7 69.2 0.0089 13.6 15.2 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF3584) BRE1 PF08647.11 CCD27184.1 - 0.0029 17.6 12.8 0.0029 17.6 12.8 7.1 4 2 3 7 7 6 3 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 CCD27184.1 - 0.0042 17.6 72.7 0.055 13.9 11.6 4.8 2 1 2 4 4 4 2 Fez1 APG6_N PF17675.1 CCD27184.1 - 0.0048 17.4 83.8 0.0061 17.1 14.8 5.1 2 1 3 5 5 4 2 Apg6 coiled-coil region BST2 PF16716.5 CCD27184.1 - 0.0059 17.2 5.3 0.0059 17.2 5.3 7.7 5 4 3 8 8 7 1 Bone marrow stromal antigen 2 Mce4_CUP1 PF11887.8 CCD27184.1 - 0.0076 15.7 4.5 0.0076 15.7 4.5 3.5 4 0 0 4 4 4 1 Cholesterol uptake porter CUP1 of Mce4, putative ABC_tran_CTD PF16326.5 CCD27184.1 - 0.0079 16.4 16.0 0.013 15.7 4.3 7.6 4 2 4 8 8 8 2 ABC transporter C-terminal domain Atg14 PF10186.9 CCD27184.1 - 0.016 14.3 78.0 0.009 15.1 14.7 4.3 2 1 2 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 NPV_P10 PF05531.12 CCD27184.1 - 0.022 15.2 4.0 0.022 15.2 4.0 7.5 4 2 2 6 6 6 0 Nucleopolyhedrovirus P10 protein ZapB PF06005.12 CCD27184.1 - 0.024 15.1 8.2 0.024 15.1 8.2 8.3 3 3 3 6 6 4 0 Cell division protein ZapB MAD PF05557.13 CCD27184.1 - 0.052 11.9 76.2 0.015 13.7 2.6 4.2 2 1 1 4 4 4 0 Mitotic checkpoint protein Filament PF00038.21 CCD27184.1 - 0.081 12.5 71.1 0.9 9.1 40.6 4.8 2 2 2 4 4 4 0 Intermediate filament protein DUF4407 PF14362.6 CCD27184.1 - 0.089 12.1 44.8 0.17 11.2 3.9 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 CCD27184.1 - 0.11 12.5 92.4 0.082 12.9 13.9 5.7 2 1 4 6 6 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 CCD27184.1 - 0.2 11.7 49.5 0.11 12.5 6.5 5.6 2 2 1 5 5 5 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 CCD27184.1 - 0.34 11.0 87.1 0.34 11.0 17.8 5.4 2 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus FPP PF05911.11 CCD27184.1 - 0.51 8.5 84.5 1.4 7.0 11.8 2.6 2 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF4164 PF13747.6 CCD27184.1 - 1.6 9.0 42.9 0.033 14.5 4.6 5.3 4 2 0 4 4 4 0 Domain of unknown function (DUF4164) DUF812 PF05667.11 CCD27184.1 - 4.1 6.2 76.0 0.38 9.6 15.8 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF812) DUF948 PF06103.11 CCD27184.1 - 4.8 7.5 35.3 0.99 9.7 1.8 6.0 2 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Taxilin PF09728.9 CCD27184.1 - 8.4 5.5 80.2 0.17 11.1 20.2 4.3 2 1 2 4 4 4 0 Myosin-like coiled-coil protein GP24_25 PF17388.2 CCD27185.1 - 0.025 14.6 2.1 0.041 13.9 0.2 2.2 2 1 0 2 2 2 0 Tail assembly gene products 24 & 25 Peptidase_M61 PF05299.12 CCD27185.1 - 0.27 11.6 2.3 0.97 9.8 0.3 2.1 2 0 0 2 2 2 0 M61 glycyl aminopeptidase zf-Tim10_DDP PF02953.15 CCD27186.1 - 3.4e-21 74.6 3.0 4.7e-21 74.2 3.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tti2 PF10521.9 CCD27187.1 - 3e-49 168.0 5.9 5.1e-49 167.3 5.9 1.3 1 0 0 1 1 1 1 Tti2 family Aminotran_4 PF01063.19 CCD27188.1 - 7.1e-35 120.9 0.0 8.7e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Ribosomal_S4e PF00900.20 CCD27189.1 - 7.5e-39 131.5 1.0 5.9e-38 128.6 0.7 2.1 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 CCD27189.1 - 1.1e-25 89.0 0.0 2.8e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CCD27189.1 - 2.4e-19 69.2 6.9 2.4e-19 69.2 6.9 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 CCD27189.1 - 4.2e-08 32.8 0.6 8.5e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 CCD27189.1 - 3.7e-06 26.7 2.1 3.7e-06 26.7 2.1 3.0 4 0 0 4 4 4 1 KOW motif dCache_2 PF08269.11 CCD27189.1 - 0.04 13.1 0.1 0.12 11.5 0.0 1.8 1 1 1 2 2 2 0 Cache domain PMT PF02366.18 CCD27190.1 - 2.2e-83 279.6 18.3 2.2e-83 279.6 18.3 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCD27190.1 - 2.9e-58 196.8 9.0 2.9e-58 196.8 9.0 3.9 4 0 0 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCD27190.1 - 3.1e-23 82.6 0.1 4.8e-23 82.0 0.1 1.2 1 0 0 1 1 1 1 MIR domain DUF4743 PF15916.5 CCD27191.1 - 5.2e-10 39.3 0.0 7.9e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 CCD27191.1 - 4.3e-07 30.0 0.0 8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain HECT_2 PF09814.9 CCD27192.1 - 1e-72 245.1 0.1 1.1e-72 245.0 0.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding RIG-I_C-RD PF11648.8 CCD27192.1 - 0.24 11.6 2.2 9.2 6.5 0.3 2.4 2 0 0 2 2 2 0 C-terminal domain of RIG-I DUF3431 PF11913.8 CCD27193.1 - 0.069 12.9 0.4 0.16 11.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3431) TPR_6 PF13174.6 CCD27193.1 - 0.17 12.6 0.8 3.1 8.6 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat IML1 PF12257.8 CCD27194.1 - 1.9e-102 342.3 3.0 4.9e-102 340.9 3.0 1.8 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 CCD27194.1 - 2.5e-25 88.3 0.4 5.7e-25 87.2 0.4 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) NIR_SIR PF01077.22 CCD27195.1 - 9.9e-51 171.4 0.0 4.9e-47 159.4 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 CCD27195.1 - 6.7e-28 96.3 0.1 3.6e-13 49.2 0.0 2.8 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 CCD27195.1 - 2e-26 92.9 0.0 4.6e-26 91.7 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin PDZ_2 PF13180.6 CCD27195.1 - 0.032 14.6 0.2 0.13 12.6 0.1 2.1 2 0 0 2 2 2 0 PDZ domain Sir1 PF11603.8 CCD27196.1 - 1.9e-51 173.6 12.0 8e-27 94.1 0.1 3.3 3 0 0 3 3 3 3 Regulatory protein Sir1 DUF273 PF03314.14 CCD27196.1 - 0.0062 16.1 0.8 0.032 13.8 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF273 C-C_Bond_Lyase PF15617.6 CCD27196.1 - 0.082 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold Flo11 PF10182.9 CCD27198.1 - 2e-68 229.3 0.5 4.6e-68 228.1 0.5 1.6 1 0 0 1 1 1 1 Flo11 domain Sir1 PF11603.8 CCD27200.1 - 2.2e-35 121.8 4.7 6.9e-35 120.1 4.7 1.9 1 0 0 1 1 1 1 Regulatory protein Sir1 Helicase_C PF00271.31 CCD27200.1 - 2.1e-15 57.0 0.2 1.2e-14 54.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCD27200.1 - 0.00032 20.5 0.0 0.00064 19.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CCD27200.1 - 0.041 13.1 0.2 0.076 12.2 0.2 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CCD27200.1 - 0.059 13.4 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sir1 PF11603.8 CCD27201.1 - 3e-36 124.5 3.3 3e-36 124.5 3.3 2.2 2 0 0 2 2 2 1 Regulatory protein Sir1 Helicase_C PF00271.31 CCD27201.1 - 3.3e-15 56.4 0.0 1.2e-14 54.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCD27201.1 - 3.1e-08 33.6 0.0 8e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CCD27201.1 - 0.017 15.1 0.0 0.063 13.3 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PND PF17949.1 CCD27201.1 - 0.15 12.3 0.5 1.6 9.0 0.0 2.6 2 0 0 2 2 2 0 FANCM pseudonuclease domain Ribonuclease_3 PF00636.26 CCD27203.1 - 3.2e-19 69.5 0.3 1.2e-18 67.7 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CCD27203.1 - 4.8e-14 52.6 0.0 1.2e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 CCD27203.1 - 2.7e-10 40.8 0.0 1.6e-07 32.0 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif Gemin6 PF06372.12 CCD27203.1 - 0.076 12.6 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 Gemin6 protein Fungal_trans_2 PF11951.8 CCD27204.1 - 1.5e-108 363.1 2.8 2.1e-108 362.6 2.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD27204.1 - 1.3e-11 44.4 8.9 2.5e-11 43.5 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dpoe2NT PF12213.8 CCD27204.1 - 0.063 13.6 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal ERO1 PF04137.15 CCD27205.1 - 1.9e-110 369.4 5.6 2.4e-110 369.1 5.6 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ImcF-related_N PF14331.6 CCD27205.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 ImcF-related N-terminal domain Kelch_4 PF13418.6 CCD27205.1 - 0.12 12.3 0.1 0.46 10.5 0.1 1.9 1 1 0 1 1 1 0 Galactose oxidase, central domain VPS9 PF02204.18 CCD27206.1 - 3.3e-27 94.7 0.1 8.3e-27 93.4 0.0 1.7 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 CCD27206.1 - 7e-13 48.7 0.8 4.5e-12 46.1 0.4 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) CUE PF02845.16 CCD27206.1 - 3.8e-11 42.5 0.0 7.5e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 CUE domain Asn_synthase PF00733.21 CCD27207.1 - 7.8e-20 71.8 0.3 3.8e-10 40.0 0.0 3.0 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CCD27207.1 - 1.7e-10 40.9 0.4 2.7e-08 33.8 0.1 3.4 3 1 0 3 3 3 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CCD27207.1 - 0.00051 20.2 0.0 0.0033 17.6 0.0 2.3 2 1 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CCD27207.1 - 0.017 14.6 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Aluminium induced protein Rad10 PF03834.14 CCD27208.1 - 3.1e-36 123.9 0.8 3.9e-36 123.5 0.8 1.1 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Med26_C PF15693.5 CCD27208.1 - 0.1 12.8 1.1 14 5.8 0.0 2.1 1 1 1 2 2 2 0 Mediator complex subunit 26 C-terminal Prefoldin PF02996.17 CCD27209.1 - 1.8e-24 86.0 1.3 1.8e-24 86.0 1.3 1.4 1 1 0 1 1 1 1 Prefoldin subunit PHM7_cyt PF14703.6 CCD27209.1 - 0.0085 16.3 7.3 0.013 15.8 7.1 1.5 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter LMBR1 PF04791.16 CCD27209.1 - 1.3 7.8 5.0 1.5 7.7 5.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Utp14 PF04615.13 CCD27210.1 - 6e-204 679.8 80.7 6e-204 679.8 80.7 2.1 1 1 1 2 2 2 1 Utp14 protein RPM2 PF08579.11 CCD27211.1 - 2.1e-43 147.5 3.8 2.1e-43 147.5 3.8 6.1 5 2 1 6 6 6 1 Mitochondrial ribonuclease P subunit (RPM2) PPR_2 PF13041.6 CCD27211.1 - 0.037 14.2 4.7 10 6.4 0.3 4.9 5 0 0 5 5 5 0 PPR repeat family DUF1122 PF06557.11 CCD27211.1 - 0.25 10.8 3.5 1.7 8.1 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1122) HMG_CoA_synt_C PF08540.10 CCD27212.1 - 7.9e-114 380.0 3.7 1e-113 379.6 3.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 CCD27212.1 - 7.1e-97 322.3 0.3 9.9e-97 321.8 0.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal F-box-like PF12937.7 CCD27213.1 - 9.6e-11 41.4 0.1 1.6e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 F-box-like UIM PF02809.20 CCD27213.1 - 2.8e-06 26.8 26.9 0.00029 20.6 2.2 4.7 4 0 0 4 4 4 3 Ubiquitin interaction motif F-box PF00646.33 CCD27213.1 - 7.3e-06 25.7 0.1 1.4e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CCD27213.1 - 0.039 13.8 0.5 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 F-box RAP80_UIM PF18282.1 CCD27213.1 - 2 8.2 11.6 2.5 7.9 2.5 3.4 3 0 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif ALO PF04030.14 CCD27214.1 - 1.3e-86 290.7 0.6 1.6e-86 290.3 0.6 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 CCD27214.1 - 1.9e-25 89.2 0.0 2.7e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CCD27214.1 - 0.016 15.3 0.2 0.031 14.4 0.2 1.5 1 0 0 1 1 1 0 Berberine and berberine like Tubulin PF00091.25 CCD27216.1 - 3.5e-67 226.4 0.0 5.1e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CCD27216.1 - 1.7e-49 167.2 0.1 2.7e-49 166.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Hydrolase_4 PF12146.8 CCD27216.1 - 0.14 11.4 0.1 0.3 10.3 0.1 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Sugar_tr PF00083.24 CCD27217.1 - 2.3e-46 158.6 12.8 3.6e-46 158.0 12.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD27217.1 - 1.9e-20 73.1 13.7 1.9e-12 46.8 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAM178 PF14816.6 CCD27217.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 SQS_PSY PF00494.19 CCD27218.1 - 1.7e-41 142.5 0.0 2.1e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase CNV-Replicase_N PF16688.5 CCD27218.1 - 0.016 15.5 0.1 0.039 14.3 0.1 1.6 1 0 0 1 1 1 0 Replicase polyprotein N-term from Coronavirus nsp1 Hyphal_reg_CWP PF11765.8 CCD27219.1 - 5.1e-32 111.1 18.3 5.1e-32 111.1 18.3 1.6 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal DUF5525 PF17663.1 CCD27219.1 - 0.019 13.1 7.8 0.023 12.8 7.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) Pept_tRNA_hydro PF01195.19 CCD27220.1 - 9.9e-36 123.3 0.0 1.2e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase RNB PF00773.19 CCD27221.1 - 4.7e-57 193.8 2.1 4.7e-57 193.8 2.1 2.4 2 1 0 2 2 2 1 RNB domain Flocculin PF00624.18 CCD27221.1 - 0.032 14.5 0.3 0.1 12.8 0.3 1.9 1 0 0 1 1 1 0 Flocculin repeat PIG-L PF02585.17 CCD27222.1 - 1.3e-18 67.9 0.0 1.9e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.7 CCD27223.1 - 7.3e-26 90.3 0.7 1.7e-24 85.9 0.2 2.8 2 0 0 2 2 2 1 Mitochondrial ATPase expression LptF_LptG PF03739.14 CCD27223.1 - 0.096 11.5 0.1 0.17 10.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF3504 PF12012.8 CCD27223.1 - 0.11 12.4 1.3 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) Rit1_C PF17184.4 CCD27224.1 - 9e-96 320.5 0.0 1.5e-95 319.8 0.0 1.3 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 CCD27224.1 - 6.1e-29 100.5 1.5 1.1e-28 99.7 0.3 2.0 2 0 0 2 2 2 1 Rit1 DUSP-like domain DSPc PF00782.20 CCD27224.1 - 0.021 14.6 0.1 0.067 13.0 0.1 1.8 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain RVT_1 PF00078.27 CCD27225.1 - 5e-31 107.9 0.1 9.1e-31 107.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CCD27225.1 - 2.2e-28 98.2 0.0 5.9e-28 96.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCD27225.1 - 4.5e-28 97.6 0.0 1e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CCD27225.1 - 1.6e-17 63.3 2.4 1.6e-17 63.3 2.4 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Peptidase_A2B PF12384.8 CCD27225.1 - 2.2e-17 63.2 0.1 4.9e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Ty3 transposon peptidase rve PF00665.26 CCD27225.1 - 1.2e-14 54.5 0.1 3.6e-14 53.0 0.0 1.8 2 0 0 2 2 1 1 Integrase core domain Asp_protease_2 PF13650.6 CCD27225.1 - 3.8e-05 24.2 0.0 7.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 CCD27225.1 - 0.00023 21.3 1.1 0.0014 18.8 0.1 2.7 2 0 0 2 2 2 1 H2C2 zinc finger RVP_2 PF08284.11 CCD27225.1 - 0.015 15.0 0.1 0.031 14.0 0.1 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CCD27225.1 - 0.018 15.6 0.0 0.037 14.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease TAXi_N PF14543.6 CCD27225.1 - 0.22 11.7 0.2 6.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal Retrotrans_gag PF03732.17 CCD27226.1 - 7.5e-05 22.9 0.1 0.00014 22.1 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 CCD27226.1 - 0.0087 16.1 5.5 0.019 15.0 5.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CCD27226.1 - 0.1 12.6 3.1 0.21 11.6 3.1 1.5 1 0 0 1 1 1 0 Zinc knuckle P53_TAD PF08563.11 CCD27226.1 - 0.13 11.7 1.3 0.24 10.9 1.3 1.4 1 0 0 1 1 1 0 P53 transactivation motif Ku PF02735.16 CCD27227.1 - 2.3e-34 118.9 0.3 5.1e-34 117.8 0.3 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CCD27227.1 - 5.7e-30 104.7 1.7 1.2e-29 103.7 1.7 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CCD27227.1 - 1.5e-05 25.6 7.1 7.6e-05 23.3 5.4 3.0 2 1 0 2 2 2 1 Ku70/Ku80 C-terminal arm Exo_endo_phos PF03372.23 CCD27228.1 - 2.1e-29 102.7 0.0 2.6e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Hyphal_reg_CWP PF11765.8 CCD27229.1 - 1.1e-28 100.2 17.0 1.4e-28 99.8 17.0 1.1 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Fungal_trans PF04082.18 CCD27230.1 - 3.5e-28 98.4 15.4 3.5e-28 98.4 15.4 2.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCD27230.1 - 4.5e-10 39.5 13.3 8.1e-10 38.7 13.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CCD27231.1 - 3.5e-32 111.7 59.8 4.2e-31 108.2 56.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCD27231.1 - 7.6e-09 34.9 25.0 1.2e-05 24.3 7.3 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter Ac76 PF05814.11 CCD27231.1 - 5.3 7.1 6.5 1 9.4 1.7 2.4 2 0 0 2 2 2 0 Orf76 (Ac76) PGM_PMM_I PF02878.16 CCD27232.1 - 1.3e-40 138.3 0.0 3.1e-40 137.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CCD27232.1 - 6.3e-21 74.9 0.0 1.4e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CCD27232.1 - 1e-12 48.2 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CCD27232.1 - 7.9e-06 26.0 0.0 2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain NIF PF03031.18 CCD27233.1 - 8.7e-25 87.3 0.3 7.3e-24 84.3 0.0 2.6 3 1 0 3 3 3 1 NLI interacting factor-like phosphatase BRCT PF00533.26 CCD27233.1 - 1.6e-12 47.6 0.2 4.9e-12 46.1 0.1 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CCD27233.1 - 4.1e-05 23.4 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 CCD27233.1 - 0.006 17.0 0.0 0.018 15.5 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CCD27233.1 - 0.04 14.2 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Exonuc_VII_L PF02601.15 CCD27233.1 - 2.8 7.4 7.9 4.5 6.8 7.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MULE PF10551.9 CCD27234.1 - 2.2e-06 28.0 0.0 4.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 CCD27234.1 - 0.0068 15.3 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Transposase, Mutator family EIIBC-GUT_N PF03612.14 CCD27234.1 - 0.19 11.5 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus ubiquitin PF00240.23 CCD27235.1 - 2.7e-19 68.7 0.1 4.1e-19 68.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CCD27235.1 - 1.3e-07 31.3 0.1 2.5e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 CCD27235.1 - 1.7e-07 31.0 0.1 1.7e-07 31.0 0.1 2.5 3 0 0 3 3 3 1 UBA/TS-N domain CUE PF02845.16 CCD27235.1 - 0.0024 17.6 0.0 0.005 16.5 0.0 1.6 1 0 0 1 1 1 1 CUE domain TBK1_ULD PF18396.1 CCD27235.1 - 0.003 17.5 0.1 0.0062 16.4 0.1 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 CCD27235.1 - 0.013 16.0 0.1 0.03 14.8 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CCD27235.1 - 0.025 14.7 0.1 0.069 13.3 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CCD27235.1 - 0.072 13.7 0.1 0.072 13.7 0.1 1.8 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain HOIP-UBA PF16678.5 CCD27235.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair CC190 PF15768.5 CCD27235.1 - 0.57 10.2 1.9 1.1 9.3 1.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 Bul1_N PF04425.12 CCD27236.1 - 1.5e-163 544.8 7.0 1.5e-163 544.8 7.0 3.2 3 0 0 3 3 3 1 Bul1 N terminus Bul1_C PF04426.12 CCD27236.1 - 1.9e-96 322.6 25.4 1.9e-96 322.6 25.4 4.5 3 2 0 4 4 4 1 Bul1 C terminus Ribosomal_S13_N PF08069.12 CCD27236.1 - 2.6 8.1 6.8 6.7 6.8 0.1 3.6 3 0 0 3 3 3 0 Ribosomal S13/S15 N-terminal domain CPBP PF02517.16 CCD27237.1 - 3.4e-13 49.8 7.1 6.4e-13 48.9 7.1 1.6 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease DUF1774 PF08611.10 CCD27237.1 - 0.15 12.4 1.9 0.59 10.5 1.8 2.1 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF1774) FA_hydroxylase PF04116.13 CCD27238.1 - 1.6e-13 51.1 14.1 1.6e-13 51.1 14.1 1.9 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Cyt-b5 PF00173.28 CCD27238.1 - 2.8e-12 46.6 0.0 9.4e-12 44.9 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Anth_synt_I_N PF04715.13 CCD27238.1 - 0.0059 16.8 0.3 0.02 15.1 0.1 1.9 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region RL11D PF11088.8 CCD27238.1 - 0.14 12.5 0.1 0.28 11.5 0.1 1.4 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Pribosyltran PF00156.27 CCD27239.1 - 7.9e-17 61.2 0.1 1.2e-16 60.7 0.1 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain SipA PF09052.10 CCD27239.1 - 0.045 13.4 0.0 0.087 12.4 0.0 1.4 1 0 0 1 1 1 0 SipA N-terminal domain RRN9 PF10680.9 CCD27240.1 - 4.4e-15 55.7 0.5 4.4e-15 55.7 0.5 3.0 4 0 0 4 4 4 1 RNA polymerase I specific transcription initiation factor G-patch PF01585.23 CCD27241.1 - 0.0038 17.1 0.4 0.02 14.7 0.4 2.3 1 1 0 1 1 1 1 G-patch domain GAGA_bind PF06217.12 CCD27241.1 - 0.0048 17.2 17.7 0.0054 17.0 17.7 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family AAA_11 PF13086.6 CCD27241.1 - 0.27 11.0 17.8 0.55 10.0 17.8 1.5 1 1 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.12 CCD27241.1 - 0.28 11.0 20.7 0.33 10.7 20.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PA26 PF04636.13 CCD27241.1 - 0.38 9.6 9.9 0.5 9.2 9.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) XRN_M PF17846.1 CCD27241.1 - 2 7.3 13.7 2.4 7.0 13.7 1.1 1 0 0 1 1 1 0 Xrn1 helical domain SAPS PF04499.15 CCD27241.1 - 2.6 6.7 13.3 3 6.5 13.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 CCD27241.1 - 2.7 8.0 7.2 3.3 7.7 7.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SLC12 PF03522.15 CCD27241.1 - 3.2 6.7 17.7 3.5 6.5 17.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 MCM_bind PF09739.9 CCD27241.1 - 3.8 5.9 16.3 4.5 5.6 16.3 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor VIR_N PF15912.5 CCD27241.1 - 5.6 6.5 11.8 7.7 6.0 11.8 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal RRM_1 PF00076.22 CCD27242.1 - 2.7e-35 120.0 1.6 1.5e-13 50.3 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCD27242.1 - 1.1e-33 114.9 1.2 1.8e-26 91.8 0.0 4.3 4 1 0 4 4 4 3 Occluded RNA-recognition motif Lsm_interact PF05391.11 CCD27242.1 - 1.1e-07 31.1 1.2 4.4e-07 29.2 1.2 2.1 1 0 0 1 1 1 1 Lsm interaction motif Nup35_RRM_2 PF14605.6 CCD27242.1 - 0.00042 20.3 0.0 0.56 10.2 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CCD27242.1 - 0.00043 19.9 0.1 1.5 8.4 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Csm2_III-A PF03750.13 CCD27242.1 - 0.001 19.9 0.6 0.3 11.9 0.1 2.8 2 0 0 2 2 2 1 Csm2 Type III-A PHM7_cyt PF14703.6 CCD27242.1 - 0.0011 19.2 0.8 2.7 8.2 0.0 3.7 2 1 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter Hs1pro-1_N PF07231.12 CCD27242.1 - 0.041 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Hs1pro-1 N-terminus Pyrophosphatase PF00719.19 CCD27243.1 - 6.8e-54 182.0 0.2 8.8e-54 181.6 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase SNAP PF14938.6 CCD27244.1 - 7.5e-106 353.7 8.4 8.5e-106 353.5 8.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 CCD27244.1 - 0.00027 21.4 0.4 70 4.4 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCD27244.1 - 0.00031 21.0 1.5 0.09 13.1 0.0 3.6 2 2 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCD27244.1 - 0.044 13.6 2.8 33 4.5 0.1 5.1 5 2 1 6 6 6 0 Tetratricopeptide repeat Endonuc-MspI PF09208.10 CCD27244.1 - 0.088 12.2 1.4 0.16 11.4 0.2 1.8 2 0 0 2 2 2 0 Restriction endonuclease MspI TPR_10 PF13374.6 CCD27244.1 - 0.11 12.4 0.6 18 5.3 0.0 3.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCD27244.1 - 0.16 12.1 0.8 5.7 7.2 0.0 3.6 3 2 1 4 4 4 0 Tetratricopeptide repeat RSN1_7TM PF02714.15 CCD27245.1 - 5.3e-91 304.7 26.6 1.1e-90 303.6 26.6 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CCD27245.1 - 5.4e-42 143.2 2.7 5.4e-42 143.2 2.7 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CCD27245.1 - 8.7e-29 101.0 1.6 1.3e-28 100.4 1.6 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 CCD27245.1 - 4.7e-26 90.8 0.0 1.4e-25 89.3 0.0 1.9 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF4618 PF15397.6 CCD27245.1 - 0.039 13.4 0.5 0.068 12.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) HAD_SAK_1 PF10307.9 CCD27246.1 - 2e-63 213.9 0.1 3e-63 213.3 0.1 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins DUF3841 PF12952.7 CCD27246.1 - 0.047 13.5 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3841) Cue1_U7BR PF18499.1 CCD27247.1 - 1.5e-22 79.4 6.2 2.4e-22 78.7 6.2 1.3 1 0 0 1 1 1 1 Ubc7p-binding region of Cue1 CUE PF02845.16 CCD27247.1 - 2.2e-09 36.8 0.0 4.2e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain DUF4834 PF16118.5 CCD27247.1 - 0.014 16.3 1.0 0.032 15.2 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CE2_N PF17996.1 CCD27247.1 - 0.074 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal Secretin_N_2 PF07655.13 CCD27247.1 - 2.4 8.7 12.8 1.7 9.3 7.4 2.3 3 0 0 3 3 3 0 Secretin N-terminal domain SAP30_Sin3_bdg PF13867.6 CCD27248.1 - 4.2e-07 30.2 8.9 5.6e-06 26.6 0.0 3.1 4 0 0 4 4 4 2 Sin3 binding region of histone deacetylase complex subunit SAP30 TerB_C PF15615.6 CCD27248.1 - 0.18 12.1 0.3 0.35 11.2 0.3 1.5 1 1 0 1 1 1 0 TerB-C domain FXMRP1_C_core PF12235.8 CCD27248.1 - 1.7 9.3 7.9 1.6 9.4 6.1 1.7 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal DUF3439 PF11921.8 CCD27248.1 - 7.6 6.5 9.6 11 5.9 9.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TatD_DNase PF01026.21 CCD27249.1 - 9.8e-38 130.0 0.3 1.3e-37 129.6 0.3 1.1 1 0 0 1 1 1 1 TatD related DNase eIF-1a PF01176.19 CCD27250.1 - 1.7e-20 72.6 0.1 2.4e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF2428 PF10350.9 CCD27251.1 - 2e-52 178.2 0.4 1.2e-51 175.6 0.1 2.4 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 CCD27251.1 - 4.7e-06 26.4 0.0 0.84 10.1 0.0 5.3 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 CCD27251.1 - 0.032 14.6 0.0 0.7 10.3 0.0 2.9 2 0 0 2 2 2 0 HEAT repeats CRISPR_Cas9_WED PF18061.1 CCD27251.1 - 0.21 11.7 3.2 2.8 8.0 0.1 3.3 3 0 0 3 3 3 0 CRISPR-Cas9 WED domain CCM2_C PF16545.5 CCD27253.1 - 5.4 7.6 8.9 0.45 11.1 0.9 3.3 4 0 0 4 4 4 0 Cerebral cavernous malformation protein, harmonin-homology DUF3699 PF12480.8 CCD27254.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3699) COX7a PF02238.15 CCD27255.1 - 1.2e-22 80.0 0.6 1.4e-22 79.9 0.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII GFD1 PF17331.2 CCD27256.1 - 4.5e-05 23.5 11.2 0.00012 22.1 11.2 1.8 1 0 0 1 1 1 1 GFD1 mRNA transport factor SR-25 PF10500.9 CCD27256.1 - 8.8 5.9 22.1 12 5.4 22.1 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein EamA PF00892.20 CCD27257.1 - 1.6e-28 99.6 33.3 2.9e-16 59.9 8.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 CCD27257.1 - 3.8e-05 23.4 16.4 7.9e-05 22.3 16.4 1.4 1 1 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 CCD27257.1 - 0.018 14.0 6.5 0.034 13.1 6.5 1.5 1 0 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like Mg_trans_NIPA PF05653.14 CCD27257.1 - 0.087 11.9 9.3 0.026 13.6 4.1 2.5 3 0 0 3 3 3 0 Magnesium transporter NIPA TMEM234 PF10639.9 CCD27257.1 - 0.94 9.5 5.2 1 9.4 1.9 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 TPT PF03151.16 CCD27257.1 - 1.8 7.8 14.2 0.026 13.9 2.5 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF2070 PF09843.9 CCD27257.1 - 5.5 5.1 23.6 0.48 8.6 8.4 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) UPF0060 PF02694.15 CCD27257.1 - 7 6.9 11.8 16 5.8 0.5 2.8 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family DUF3217 PF11506.8 CCD27258.1 - 0.021 14.8 0.9 0.78 9.7 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3217) Paramyxo_P_V_N PF13825.6 CCD27259.1 - 0.17 11.3 2.4 0.18 11.2 2.4 1.0 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus Pyridoxal_deC PF00282.19 CCD27260.1 - 8.5e-54 182.7 0.0 1.3e-53 182.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain OKR_DC_1 PF01276.20 CCD27260.1 - 0.054 12.2 0.0 0.085 11.6 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Cnd1 PF12717.7 CCD27260.1 - 0.16 12.0 0.8 0.31 11.1 0.2 1.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 SAM_decarbox PF01536.16 CCD27261.1 - 2.5e-136 454.4 6.8 2.8e-136 454.2 6.8 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase zf-RING_2 PF13639.6 CCD27262.1 - 2.9e-07 30.7 7.2 6.2e-07 29.6 7.2 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 CCD27262.1 - 3.2e-05 24.0 5.5 0.00011 22.4 5.5 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 CCD27262.1 - 6.3e-05 23.2 6.8 0.00015 22.0 6.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CCD27262.1 - 0.00016 21.7 1.2 0.00038 20.5 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CCD27262.1 - 0.0055 16.6 8.0 0.012 15.5 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NopRA1 PF16201.5 CCD27262.1 - 0.044 13.4 4.0 10 5.6 0.1 4.1 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 RINGv PF12906.7 CCD27262.1 - 0.048 13.8 5.7 0.099 12.8 5.7 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.6 CCD27262.1 - 0.055 13.3 7.6 0.12 12.3 7.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CCD27262.1 - 0.085 12.7 5.5 0.69 9.7 0.9 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CCD27262.1 - 0.09 12.6 5.4 1.5 8.7 5.4 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RE_XamI PF09572.10 CCD27262.1 - 0.099 12.3 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 XamI restriction endonuclease zf-RING-like PF08746.11 CCD27262.1 - 0.17 12.2 7.1 0.38 11.1 7.1 1.7 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 CCD27262.1 - 0.27 10.9 4.4 0.57 9.8 4.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CCD27262.1 - 1.8 8.5 6.0 1.3 8.9 0.5 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 CCD27262.1 - 3.2 7.7 6.4 6.9 6.7 6.4 1.6 1 0 0 1 1 1 0 PHD-finger Glyco_transf_8 PF01501.20 CCD27263.1 - 0.0012 18.5 5.0 0.0019 17.8 2.7 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 CCD27263.1 - 0.0058 16.0 0.3 0.01 15.2 0.3 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative VPS28 PF03997.12 CCD27264.1 - 0.15 11.7 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 VPS28 protein AMP-binding PF00501.28 CCD27265.1 - 1.2e-86 290.9 0.0 1.7e-86 290.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCD27265.1 - 0.001 20.0 0.1 0.0061 17.5 0.0 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain COX6B PF02297.17 CCD27266.1 - 1.3e-22 79.9 7.0 1.6e-22 79.5 7.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Bac_rhodopsin PF01036.18 CCD27267.1 - 1.5e-45 155.5 21.3 2e-45 155.1 21.3 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein XhlA PF10779.9 CCD27267.1 - 0.21 11.8 0.6 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Haemolysin XhlA DUF2070 PF09843.9 CCD27267.1 - 8.8 4.5 16.2 0.48 8.6 9.3 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) SUN PF03856.13 CCD27268.1 - 1.8e-76 256.8 12.3 2.5e-76 256.4 12.3 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Cation_efflux PF01545.21 CCD27269.1 - 8.6e-57 192.1 0.2 1.1e-56 191.7 0.2 1.1 1 0 0 1 1 1 1 Cation efflux family TctB PF07331.11 CCD27269.1 - 0.14 12.5 2.6 12 6.2 0.0 2.4 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Ribosomal_L18A PF01775.17 CCD27270.1 - 4.6e-53 178.4 1.6 6.8e-53 177.9 1.6 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Mito_carr PF00153.27 CCD27271.1 - 2e-30 104.5 5.1 1.1e-12 47.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF382 PF04037.13 CCD27272.1 - 5.8e-51 171.9 0.3 5.8e-51 171.9 0.3 3.2 3 1 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 CCD27272.1 - 3.3e-22 78.1 1.5 7e-22 77.0 1.5 1.6 1 0 0 1 1 1 1 PSP RNase_3_N PF18497.1 CCD27273.1 - 6.8e-39 132.4 5.6 1.7e-38 131.1 5.6 1.7 1 0 0 1 1 1 1 Ribonuclease III N-terminal domain Ribonuclease_3 PF00636.26 CCD27273.1 - 1.1e-17 64.6 0.1 1.1e-17 64.6 0.1 2.5 2 2 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CCD27273.1 - 1.8e-09 37.9 0.0 4.7e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 CCD27273.1 - 0.00014 22.5 0.1 0.0005 20.7 0.1 2.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF4228 PF14009.6 CCD27273.1 - 0.22 11.9 5.2 0.053 13.9 0.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4228) RCC1 PF00415.18 CCD27274.1 - 1.9e-18 66.8 0.2 2.2e-10 41.0 0.0 5.3 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 CCD27274.1 - 2.3e-14 53.5 1.2 6.3e-09 36.0 0.5 2.8 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.6 CCD27274.1 - 1.2e-08 34.5 9.4 0.0082 15.9 1.7 3.6 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat Glyco_hydro_76 PF03663.14 CCD27275.1 - 3.9e-157 523.5 16.4 4.7e-157 523.2 16.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 CCD27275.1 - 0.017 14.2 7.4 0.5 9.4 0.5 2.7 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 TFIID-31kDa PF02291.15 CCD27276.1 - 7e-47 158.5 1.7 1.8e-46 157.1 1.7 1.6 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Spt20 PF12090.8 CCD27276.1 - 1.2e-05 25.0 1.1 1.8e-05 24.5 1.1 1.2 1 0 0 1 1 1 1 Spt20 family Rtt102p PF09510.10 CCD27276.1 - 0.23 11.7 3.7 1.6 8.9 3.7 2.2 1 1 0 1 1 1 0 Rtt102p-like transcription regulator protein FSA_C PF10479.9 CCD27276.1 - 0.59 8.2 5.5 0.72 7.9 5.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Presenilin PF01080.17 CCD27276.1 - 1 8.0 3.6 1.4 7.6 3.4 1.3 1 1 0 1 1 1 0 Presenilin MBF1 PF08523.10 CCD27277.1 - 2.7e-23 82.2 2.6 3.2e-23 82.0 1.1 1.8 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CCD27277.1 - 3e-14 52.8 0.3 4.8e-14 52.2 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 CCD27277.1 - 4.5e-06 26.9 0.0 9.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 CCD27277.1 - 0.0025 17.8 0.2 0.0038 17.2 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain LRR_6 PF13516.6 CCD27278.1 - 2.4e-06 27.1 14.8 1.2 9.3 0.2 7.6 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.33 CCD27278.1 - 0.00014 21.9 14.2 9.4 7.2 0.1 7.3 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_4 PF12799.7 CCD27278.1 - 0.0034 17.7 33.4 0.29 11.6 1.0 7.6 4 3 3 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CCD27278.1 - 1.9 8.3 25.8 18 5.2 4.4 6.5 3 2 2 5 5 5 0 Leucine rich repeat SWIB PF02201.18 CCD27279.1 - 4.3e-28 97.0 0.1 9.3e-28 95.9 0.1 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 CCD27279.1 - 1.4e-10 41.0 0.0 6.5e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 DEK C terminal domain T3SS_HrpK1 PF16937.5 CCD27279.1 - 0.025 14.2 4.0 0.042 13.5 3.7 1.5 1 1 0 1 1 1 0 Type III secretion system translocator protein, HrpF Rep_Org_C PF06926.11 CCD27279.1 - 0.027 14.8 0.1 7.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus PI3K_1B_p101 PF10486.9 CCD27279.1 - 0.54 8.0 8.6 0.68 7.6 8.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SR-25 PF10500.9 CCD27279.1 - 5.5 6.5 29.0 0.12 11.9 13.8 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein VPS11_C PF12451.8 CCD27281.1 - 3.7e-12 46.3 1.9 8e-12 45.2 0.3 2.5 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 CCD27281.1 - 4.1e-06 26.7 6.5 4.1e-06 26.7 6.5 2.1 2 1 0 2 2 1 1 Zinc-finger zf-RING_5 PF14634.6 CCD27281.1 - 0.0012 18.7 8.9 0.0032 17.4 8.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CCD27281.1 - 0.0023 17.9 6.4 0.007 16.4 6.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CCD27281.1 - 0.021 14.9 6.8 0.069 13.3 6.8 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 CCD27281.1 - 0.026 14.1 3.5 0.054 13.1 3.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 CCD27281.1 - 0.042 14.2 8.1 0.093 13.1 8.1 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 CCD27281.1 - 0.042 13.7 8.4 0.096 12.6 8.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCD27281.1 - 0.085 12.7 8.6 0.19 11.6 8.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 CCD27281.1 - 0.086 12.7 8.1 0.17 11.8 6.5 2.3 2 0 0 2 2 2 0 PHD-finger RelB PF04221.12 CCD27281.1 - 0.087 12.8 0.2 0.33 10.9 0.2 1.9 1 0 0 1 1 1 0 RelB antitoxin Med27 PF11571.8 CCD27281.1 - 0.098 13.0 1.0 0.36 11.2 1.0 2.1 1 0 0 1 1 1 0 Mediator complex subunit 27 zf-rbx1 PF12678.7 CCD27281.1 - 0.95 9.8 6.8 0.49 10.7 4.1 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain FANCL_C PF11793.8 CCD27281.1 - 2 8.7 5.2 4.4 7.6 5.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain S10_plectin PF03501.15 CCD27282.1 - 4.6e-43 145.2 0.5 5.2e-43 145.0 0.5 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF4364 PF14277.6 CCD27282.1 - 0.016 14.9 0.2 0.021 14.6 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4364) HTH_45 PF14947.6 CCD27282.1 - 0.051 13.6 0.3 0.089 12.8 0.3 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix MsyB PF13984.6 CCD27282.1 - 0.055 13.8 0.0 0.073 13.4 0.0 1.2 1 0 0 1 1 1 0 MsyB protein PadR PF03551.14 CCD27282.1 - 0.064 13.2 0.4 0.064 13.2 0.4 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family S1 PF00575.23 CCD27283.1 - 6.9e-51 170.5 22.4 6.7e-11 42.4 0.3 11.8 11 2 0 11 11 10 8 S1 RNA binding domain TPR_19 PF14559.6 CCD27283.1 - 3.1e-07 30.8 0.0 0.0043 17.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCD27283.1 - 4.3e-05 24.0 0.1 3.3 8.8 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat Suf PF05843.14 CCD27283.1 - 0.0012 18.9 5.5 0.0075 16.3 4.7 5.2 3 1 2 6 6 6 3 Suppressor of forked protein (Suf) CSD2 PF17876.1 CCD27283.1 - 0.0051 16.9 1.0 49 4.2 0.0 4.8 4 0 0 4 4 4 0 Cold shock domain Mad3_BUB1_I PF08311.12 CCD27283.1 - 0.014 15.3 3.0 0.62 10.0 0.2 2.7 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 PCB_OB PF17092.5 CCD27283.1 - 0.018 15.8 0.8 26 5.6 0.0 5.4 6 0 0 6 6 5 0 Penicillin-binding protein OB-like domain TPR_12 PF13424.6 CCD27283.1 - 0.026 14.8 0.0 13 6.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 CCD27283.1 - 0.071 12.3 4.2 0.59 9.3 1.2 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat YlmH_RBD PF17774.1 CCD27283.1 - 0.081 13.2 0.0 0.36 11.1 0.0 2.1 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH PSD4 PF07631.11 CCD27283.1 - 0.19 12.3 1.2 0.57 10.7 1.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) BSP_II PF05432.11 CCD27283.1 - 4.3 7.0 24.7 0.93 9.1 3.1 3.3 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) TRAM PF01938.20 CCD27283.1 - 7.2 6.7 7.9 2.4 8.2 0.0 4.3 6 0 0 6 6 4 0 TRAM domain RrnaAD PF00398.20 CCD27284.1 - 1.5e-53 181.6 0.6 1.8e-53 181.4 0.6 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TAFII55_N PF04658.13 CCD27285.1 - 2.8e-52 176.7 0.1 2.8e-52 176.7 0.1 3.0 2 1 0 2 2 2 1 TAFII55 protein conserved region SNF2_N PF00176.23 CCD27286.1 - 4e-72 242.9 0.7 1.2e-71 241.3 0.7 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCD27286.1 - 2.8e-21 76.0 1.5 3.2e-19 69.3 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.6 CCD27286.1 - 5.3e-17 62.2 2.6 5.3e-17 62.2 2.6 4.5 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex Bromodomain PF00439.25 CCD27286.1 - 4e-15 55.7 1.1 1.6e-14 53.7 1.1 2.1 1 0 0 1 1 1 1 Bromodomain QLQ PF08880.11 CCD27286.1 - 1.4e-10 40.8 0.6 6.6e-10 38.6 0.6 2.3 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 CCD27286.1 - 6.1e-08 32.8 0.0 6.1e-08 32.8 0.0 3.6 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HSA PF07529.13 CCD27286.1 - 0.00027 21.2 10.5 0.00027 21.2 10.5 3.6 4 0 0 4 4 4 1 HSA Tristanin_u2 PF16638.5 CCD27286.1 - 0.00044 21.1 1.0 0.00044 21.1 1.0 7.5 6 3 2 8 8 8 1 Unstructured region on methyltransferase between zinc-fingers MFS_1 PF07690.16 CCD27287.1 - 3.8e-07 29.4 32.8 1.4e-06 27.5 30.5 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily FSH1 PF03959.13 CCD27288.1 - 9.7e-59 198.6 0.0 1.1e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CCD27288.1 - 0.0004 20.3 0.0 0.0045 16.8 0.0 2.2 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 CCD27288.1 - 0.05 13.2 0.2 3.2 7.3 0.0 2.8 2 1 1 3 3 3 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCD27288.1 - 0.17 11.1 0.0 0.67 9.2 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Mre11_DNA_bind PF04152.14 CCD27289.1 - 2.4e-49 167.9 4.4 2.4e-49 167.9 4.4 3.2 2 1 1 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CCD27289.1 - 4.6e-11 43.6 1.6 1e-10 42.5 1.6 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CCD27289.1 - 0.014 15.6 0.0 0.21 11.7 0.0 2.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RNR_N PF08343.10 CCD27289.1 - 1.4 9.0 7.2 20 5.3 0.1 3.7 3 1 0 3 3 3 0 Ribonucleotide reductase N-terminal AMMECR1 PF01871.17 CCD27290.1 - 2.1e-36 125.0 0.0 2.5e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 adh_short PF00106.25 CCD27291.1 - 2.2e-49 167.6 0.1 2.7e-49 167.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCD27291.1 - 1.3e-30 106.7 0.0 1.6e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCD27291.1 - 1.1e-08 35.2 0.0 1.6e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CCD27291.1 - 0.009 15.2 0.1 0.017 14.3 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein TRAPPC10 PF12584.8 CCD27293.1 - 1.1e-07 31.7 0.0 6.7e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 DUF3029 PF11230.8 CCD27293.1 - 0.034 12.5 0.1 0.06 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) Foie-gras_1 PF11817.8 CCD27293.1 - 0.045 13.3 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Foie gras liver health family 1 LAGLIDADG_1 PF00961.19 CCD27293.1 - 8 7.5 9.6 4.8 8.2 0.1 4.2 4 0 0 4 4 4 0 LAGLIDADG endonuclease Pkinase PF00069.25 CCD27294.1 - 3.9e-42 144.4 0.2 2.8e-20 72.8 0.5 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCD27294.1 - 6.1e-10 38.8 1.8 3e-07 30.0 0.4 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_72 PF03198.14 CCD27295.1 - 7.6e-127 422.9 6.8 1.1e-126 422.4 6.8 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 CCD27295.1 - 5.8e-05 22.3 0.1 9.3e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 CCD27295.1 - 0.007 15.8 0.1 0.021 14.3 0.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cadherin_5 PF17892.1 CCD27295.1 - 0.054 13.5 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 Cadherin-like domain DUF4073 PF13285.6 CCD27295.1 - 0.074 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) Macoilin PF09726.9 CCD27295.1 - 3.6 6.0 9.3 4.8 5.6 9.3 1.1 1 0 0 1 1 1 0 Macoilin family Myb_DNA-binding PF00249.31 CCD27296.1 - 5.1e-22 77.8 1.3 1.7e-11 44.1 0.8 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCD27296.1 - 1.1e-20 73.6 2.9 9.5e-13 48.2 0.6 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_Cef PF11831.8 CCD27296.1 - 2.9e-05 23.8 1.0 2.9e-05 23.8 1.0 2.2 2 0 0 2 2 2 1 pre-mRNA splicing factor component Rap1_C PF11626.8 CCD27296.1 - 0.0033 17.5 0.4 0.013 15.5 0.0 2.3 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain MLTR_LBD PF17765.1 CCD27296.1 - 0.19 11.8 0.1 0.36 10.9 0.1 1.3 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain Abhydrolase_1 PF00561.20 CCD27297.1 - 1.9e-14 54.0 0.1 3.6e-14 53.0 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCD27297.1 - 3.2e-07 29.8 0.0 5.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 CCD27297.1 - 0.00027 20.3 0.1 0.0006 19.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Cutinase PF01083.22 CCD27297.1 - 0.0037 17.2 0.0 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 CCD27297.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LZ3wCH PF18517.1 CCD27298.1 - 0.12 12.5 1.1 0.29 11.2 0.4 2.1 2 0 0 2 2 2 0 Leucine zipper with capping helix domain Tubulin_3 PF14881.6 CCD27299.1 - 8.3e-27 94.0 0.1 2.1e-26 92.7 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.9 CCD27299.1 - 1.7e-18 67.1 0.3 3.9e-18 65.9 0.3 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tox-REase-7 PF15649.6 CCD27299.1 - 0.017 15.4 0.1 0.065 13.6 0.1 2.0 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 7 Tubulin PF00091.25 CCD27299.1 - 0.047 13.9 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain CAP_GLY PF01302.25 CCD27301.1 - 1.7e-18 66.4 0.1 2.6e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain LPD15 PF18828.1 CCD27301.1 - 0.027 14.3 0.3 0.25 11.3 0.1 2.8 2 0 0 2 2 2 0 Large polyvalent-protein-associated domain 15 Pox_A_type_inc PF04508.12 CCD27301.1 - 0.18 11.7 16.4 0.33 10.9 0.4 6.0 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat EF-hand_1 PF00036.32 CCD27302.1 - 1.1e-26 90.4 12.8 1.9e-07 30.2 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CCD27302.1 - 9.1e-26 90.1 6.0 8.4e-14 51.8 0.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCD27302.1 - 2.6e-21 73.7 7.8 1.3e-06 27.8 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CCD27302.1 - 3.7e-16 58.7 10.7 4.7e-10 39.2 0.5 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CCD27302.1 - 3.7e-13 48.3 4.9 0.00037 19.9 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 CCD27302.1 - 5.3e-07 29.9 0.2 0.011 16.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CCD27302.1 - 4e-06 26.7 1.9 0.0012 18.7 0.1 2.4 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CCD27302.1 - 0.0017 18.7 0.4 1 9.7 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CCD27302.1 - 0.0051 16.8 0.1 0.57 10.1 0.0 2.8 1 1 1 3 3 3 1 Caleosin related protein Dockerin_1 PF00404.18 CCD27302.1 - 0.019 15.2 0.8 0.94 9.7 0.1 2.7 3 1 0 3 3 3 0 Dockerin type I domain VCBS PF13517.6 CCD27302.1 - 0.063 13.9 0.2 3.4 8.3 0.1 2.4 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Mor PF08765.11 CCD27302.1 - 0.13 12.3 0.0 0.41 10.7 0.0 1.9 2 0 0 2 2 2 0 Mor transcription activator family UbiA PF01040.18 CCD27304.1 - 3.8e-51 173.8 12.1 5.9e-51 173.2 12.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family FA_desaturase PF00487.24 CCD27304.1 - 1.2 9.0 17.0 0.034 14.0 9.2 2.0 1 1 2 3 3 3 0 Fatty acid desaturase MitMem_reg PF13012.6 CCD27305.1 - 9.1e-33 113.0 0.4 1.8e-32 112.1 0.4 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CCD27305.1 - 5e-31 107.1 0.0 5e-31 107.1 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DDHD PF02862.17 CCD27305.1 - 0.79 9.8 3.4 1.2 9.2 3.4 1.3 1 0 0 1 1 1 0 DDHD domain KilA-N PF04383.13 CCD27305.1 - 1.3 8.9 7.9 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 KilA-N domain Pkinase PF00069.25 CCD27306.1 - 7.8e-49 166.4 3.1 3.2e-48 164.4 3.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD27306.1 - 6.6e-21 74.7 3.2 5.4e-20 71.8 2.0 2.8 1 1 1 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 CCD27306.1 - 0.00061 19.5 0.3 1.2 8.7 0.1 2.9 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CCD27306.1 - 0.0013 18.1 0.2 0.01 15.2 0.1 2.5 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 CCD27306.1 - 0.045 13.7 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family GHMP_kinases_N PF00288.26 CCD27307.1 - 3.6e-18 65.5 0.0 8.3e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CCD27307.1 - 5.1e-08 33.2 0.0 1.5e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 CCD27307.1 - 0.059 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature MFA1_2 PF17317.2 CCD27308.1 - 7e-26 89.7 0.4 7.4e-26 89.6 0.4 1.0 1 0 0 1 1 1 1 Mating hormone A-factor 1&2 PIGA PF08288.12 CCD27309.1 - 1.5e-42 144.1 1.6 4.9e-42 142.4 1.6 2.0 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CCD27309.1 - 2.9e-32 112.0 0.4 5.8e-32 111.0 0.4 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CCD27309.1 - 7.4e-27 94.0 0.0 1.4e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCD27309.1 - 1.1e-22 80.9 0.1 2.7e-22 79.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CCD27309.1 - 1.1e-12 48.7 0.0 2.4e-12 47.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CCD27309.1 - 3.9e-07 30.2 0.3 8.1e-07 29.1 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 CCD27309.1 - 0.0066 16.8 0.0 0.016 15.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 CCD27309.1 - 0.028 14.1 0.1 0.17 11.6 0.0 1.9 1 1 1 2 2 2 0 Starch synthase catalytic domain Abi_2 PF07751.11 CCD27309.1 - 0.094 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Abi-like protein TFR_dimer PF04253.15 CCD27310.1 - 1.1e-26 93.2 0.0 2.3e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CCD27310.1 - 4.9e-07 29.6 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CCD27310.1 - 0.00027 20.9 0.0 0.0014 18.6 0.0 2.1 1 1 0 1 1 1 1 PA domain Cyt-b5 PF00173.28 CCD27311.1 - 2.8e-12 46.6 0.0 4e-12 46.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_9 PF18444.1 CCD27313.1 - 4.8e-30 103.2 0.7 9.2e-30 102.3 0.7 1.5 1 0 0 1 1 1 1 RNA recognition motif TAP_C PF03943.13 CCD27313.1 - 1.3e-12 47.2 0.3 1.3e-12 47.2 0.3 2.2 2 0 0 2 2 2 1 TAP C-terminal domain LRR_9 PF14580.6 CCD27313.1 - 1.7e-07 30.9 3.2 3.8e-07 29.8 3.2 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CCD27313.1 - 0.00011 22.5 17.8 0.00072 19.9 4.9 3.5 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) DUF5065 PF16723.5 CCD27313.1 - 0.04 14.0 0.2 0.1 12.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) LRR_8 PF13855.6 CCD27313.1 - 0.67 9.8 6.2 4.8 7.0 6.1 2.7 1 1 0 1 1 1 0 Leucine rich repeat DnaJ PF00226.31 CCD27314.1 - 2.6e-18 65.9 0.8 8e-18 64.3 0.8 1.9 1 0 0 1 1 1 1 DnaJ domain Ins_allergen_rp PF06757.13 CCD27314.1 - 0.019 14.9 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification Na_trans_assoc PF06512.13 CCD27314.1 - 0.12 12.7 4.1 0.29 11.4 4.1 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated Astro_capsid_p PF12226.8 CCD27314.1 - 0.61 9.2 11.1 1 8.4 11.1 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Acetyltransf_1 PF00583.25 CCD27315.1 - 3.9e-10 40.0 0.0 4.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCD27315.1 - 6.5e-07 29.3 0.0 9.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCD27315.1 - 6.8e-07 29.6 0.1 9.3e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CCD27315.1 - 0.0027 17.9 0.1 0.004 17.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCD27315.1 - 0.0038 17.2 0.0 0.0064 16.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein DNA_pol_B PF00136.21 CCD27317.1 - 1.2e-107 360.5 1.5 1.9e-107 359.8 1.5 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CCD27317.1 - 5.5e-23 81.6 4.5 9.2e-13 48.0 1.6 2.7 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CCD27317.1 - 4.8e-11 43.0 8.5 1.2e-10 41.7 8.5 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF4252 PF14060.6 CCD27317.1 - 0.0015 18.5 0.7 0.0044 16.9 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4252) HypA PF01155.19 CCD27317.1 - 0.65 10.0 5.8 0.99 9.4 1.0 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CCD27317.1 - 1.5 8.9 5.2 4.4 7.4 5.2 1.8 1 1 0 1 1 1 0 Double zinc ribbon Atg29_N PF18388.1 CCD27318.1 - 1.8e-18 66.1 1.0 3.6e-18 65.1 1.0 1.5 1 0 0 1 1 1 1 Atg29 N-terminal domain AF0941-like PF14591.6 CCD27318.1 - 0.13 12.8 2.3 0.49 11.0 0.3 2.2 1 1 1 2 2 2 0 AF0941-like SET PF00856.28 CCD27319.1 - 8.7e-10 39.2 0.8 3.4e-09 37.3 0.8 2.0 1 1 0 1 1 1 1 SET domain YHS PF04945.13 CCD27319.1 - 0.0023 18.0 0.1 0.0084 16.2 0.1 1.9 1 0 0 1 1 1 1 YHS domain Chromo_2 PF18704.1 CCD27319.1 - 0.022 15.0 0.6 0.045 14.0 0.6 1.6 1 0 0 1 1 1 0 Chromatin organization modifier domain 2 HATPase_c_3 PF13589.6 CCD27320.1 - 7.9e-11 41.9 0.1 1.5e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CCD27320.1 - 6.2e-08 33.1 0.1 1.7e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 CCD27320.1 - 0.0014 18.4 0.0 0.0038 17.0 0.0 1.7 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CCD27320.1 - 0.18 11.5 2.1 0.18 11.5 0.2 2.0 2 0 0 2 2 2 0 DNA mismatch repair protein, C-terminal domain NSP2-B_epitope PF14757.6 CCD27321.1 - 0.075 12.7 4.1 0.072 12.8 3.2 1.4 1 1 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein STIMATE PF12400.8 CCD27322.1 - 7.2e-45 152.6 7.2 7.2e-45 152.6 7.2 2.1 2 0 0 2 2 2 1 STIMATE family DUF2208 PF09973.9 CCD27322.1 - 0.041 13.5 2.6 0.2 11.3 0.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Pet20 PF08692.10 CCD27323.1 - 1.2e-13 51.9 10.1 7.4e-07 29.9 0.0 3.4 2 1 1 3 3 3 2 Mitochondrial protein Pet20 DivIC PF04977.15 CCD27323.1 - 8 6.3 7.9 4.1 7.2 4.3 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF4637 PF15470.6 CCD27324.1 - 4.6 6.9 7.0 4 7.2 1.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4637) Methyltransf_15 PF09445.10 CCD27325.1 - 2.2e-62 209.5 0.1 2.2e-62 209.5 0.1 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 CCD27325.1 - 0.0001 22.9 0.0 0.00022 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CCD27325.1 - 0.00029 20.6 0.2 0.0047 16.6 0.2 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 CCD27325.1 - 0.0023 17.7 0.0 0.0051 16.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CCD27325.1 - 0.0025 17.5 0.5 0.0065 16.1 0.0 1.9 3 0 0 3 3 3 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 CCD27325.1 - 0.15 12.7 0.1 0.63 10.7 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Pkinase PF00069.25 CCD27328.1 - 2.6e-68 230.2 0.0 3.7e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD27328.1 - 2.7e-31 108.8 0.0 3.9e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CCD27328.1 - 1.2e-10 41.9 0.5 1.2e-10 41.9 0.5 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CCD27328.1 - 3.8e-06 26.1 0.1 9.3e-06 24.8 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 CCD27328.1 - 0.0039 16.8 0.1 1 8.9 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CCD27328.1 - 0.023 14.0 0.0 0.069 12.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CCD27328.1 - 0.095 12.0 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_ligase_IV PF11411.8 CCD27328.1 - 0.12 12.5 0.2 4.5 7.5 0.1 2.7 2 0 0 2 2 2 0 DNA ligase IV SPX PF03105.19 CCD27328.1 - 0.48 10.3 7.5 0.7 9.8 7.5 1.2 1 0 0 1 1 1 0 SPX domain RRN3 PF05327.11 CCD27329.1 - 7.9e-177 589.2 12.8 9.1e-177 589.0 12.8 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 CCD27329.1 - 0.0055 15.0 20.1 0.0083 14.4 19.8 1.4 1 1 0 1 1 1 1 Nop14-like family Exo5 PF09810.9 CCD27329.1 - 0.074 12.5 4.0 0.12 11.8 3.4 1.6 2 0 0 2 2 2 0 Exonuclease V - a 5' deoxyribonuclease DUF913 PF06025.12 CCD27329.1 - 0.15 11.0 1.1 0.25 10.3 1.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SDA1 PF05285.12 CCD27329.1 - 0.17 11.3 22.2 0.24 10.8 22.2 1.1 1 0 0 1 1 1 0 SDA1 DUF1539 PF07560.11 CCD27329.1 - 0.25 11.4 2.7 0.68 10.0 0.1 2.9 2 2 1 3 3 3 0 Domain of Unknown Function (DUF1539) BUD22 PF09073.10 CCD27329.1 - 0.98 8.7 16.7 1.4 8.2 16.7 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 CCD27329.1 - 2.1 6.3 29.3 0.38 8.8 25.8 1.5 2 0 0 2 2 2 0 DNA polymerase phi FSIP1 PF15554.6 CCD27329.1 - 3.8 6.5 17.8 6.2 5.8 17.8 1.2 1 0 0 1 1 1 0 FSIP1 family RP-C_C PF11800.8 CCD27329.1 - 5.2 7.1 5.5 9.2 6.3 5.5 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Vfa1 PF08432.10 CCD27329.1 - 10 6.4 9.5 16 5.7 9.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SPRY PF00622.28 CCD27330.1 - 4.2e-13 49.5 0.0 9.2e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 SPRY domain SRP9-21 PF05486.12 CCD27331.1 - 1.7e-19 70.0 0.2 1.7e-19 70.0 0.2 2.5 2 1 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) WD40 PF00400.32 CCD27332.1 - 5.3e-16 58.7 6.8 6.9e-05 23.5 0.1 5.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCD27332.1 - 4.6e-06 26.8 0.1 0.29 11.5 0.0 4.9 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCD27332.1 - 0.018 14.0 0.0 0.14 11.0 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MFA1_2 PF17317.2 CCD27333.1 - 1.7e-23 82.1 0.0 1.8e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Mating hormone A-factor 1&2 N2227 PF07942.12 CCD27334.1 - 2.2e-56 191.0 0.7 3.9e-56 190.2 0.7 1.4 1 0 0 1 1 1 1 N2227-like protein NFRKB_winged PF14465.6 CCD27334.1 - 0.027 14.6 0.1 2.5 8.4 0.0 3.0 3 0 0 3 3 3 0 NFRKB Winged Helix-like Fungal_KA1 PF16797.5 CCD27334.1 - 0.028 14.1 0.1 8.7 6.1 0.0 2.6 2 0 0 2 2 2 0 Fungal kinase associated-1 domain SapB_1 PF05184.15 CCD27334.1 - 0.16 12.0 2.2 2 8.5 0.1 3.3 3 1 1 4 4 4 0 Saposin-like type B, region 1 PIGA PF08288.12 CCD27335.1 - 6.9e-46 154.8 2.5 2.7e-45 152.9 2.5 2.1 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CCD27335.1 - 2.1e-29 102.7 0.3 3e-29 102.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CCD27335.1 - 4.7e-29 101.1 0.0 7.6e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCD27335.1 - 1.2e-23 84.0 0.1 3.6e-23 82.5 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CCD27335.1 - 4.9e-12 46.6 0.0 6.9e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CCD27335.1 - 3.2e-06 27.2 0.4 7.1e-06 26.1 0.4 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 CCD27335.1 - 0.0085 16.5 0.2 0.029 14.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 CCD27335.1 - 0.044 13.5 0.1 0.33 10.6 0.0 2.2 1 1 1 2 2 2 0 Starch synthase catalytic domain TFR_dimer PF04253.15 CCD27336.1 - 3.7e-34 117.4 0.3 8.8e-34 116.2 0.0 1.8 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CCD27336.1 - 0.00012 21.9 0.0 0.00029 20.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CCD27336.1 - 0.00023 21.1 0.0 0.0012 18.8 0.0 2.1 1 1 0 1 1 1 1 PA domain Nicastrin PF05450.15 CCD27336.1 - 0.047 13.1 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Mito_carr PF00153.27 CCD27337.1 - 1.8e-55 184.8 4.4 9.8e-19 67.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 CCD27337.1 - 0.054 13.7 0.1 6.8 7.0 0.1 2.9 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Vma12 PF11712.8 CCD27338.1 - 1.7e-34 118.9 0.1 2.4e-34 118.4 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase eIF-5a PF01287.20 CCD27338.1 - 0.14 12.3 2.3 0.13 12.4 0.5 1.9 2 0 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold CHD5 PF04420.14 CCD27338.1 - 0.37 10.6 7.2 2.8 7.8 0.7 3.1 2 1 1 3 3 3 0 CHD5-like protein Pkinase PF00069.25 CCD27339.1 - 6.2e-41 140.5 0.0 1.1e-40 139.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD27339.1 - 2.4e-22 79.5 0.0 2.7e-21 76.0 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCD27339.1 - 0.012 14.4 0.1 0.021 13.6 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase AP_endonuc_2 PF01261.24 CCD27340.1 - 1.3e-32 113.0 0.0 2.5e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel BAF1_ABF1 PF04684.13 CCD27341.1 - 1.8e-78 265.0 30.5 1.2e-42 146.7 19.5 2.7 1 1 1 2 2 2 2 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.15 CCD27341.1 - 1e-05 25.4 0.8 0.00014 21.8 0.5 2.4 2 0 0 2 2 2 1 MuDR family transposase KTI12 PF08433.10 CCD27342.1 - 8.1e-94 314.1 3.5 9.3e-94 313.9 3.5 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 CCD27342.1 - 5.8e-06 26.9 0.0 2e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CCD27342.1 - 1.6e-05 25.1 0.0 4.2e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CCD27342.1 - 0.00011 22.4 0.1 0.0017 18.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 CCD27342.1 - 0.00026 20.9 0.0 0.00051 20.0 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 CCD27342.1 - 0.00065 20.1 0.2 0.0019 18.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CPT PF07931.12 CCD27342.1 - 0.023 14.5 0.0 0.071 12.9 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 CCD27342.1 - 0.03 14.7 0.0 0.19 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Syntaxin_2 PF14523.6 CCD27342.1 - 0.037 14.4 3.5 0.051 14.0 1.3 2.4 2 1 0 2 2 2 0 Syntaxin-like protein RNA_helicase PF00910.22 CCD27342.1 - 0.041 14.3 0.2 0.21 12.0 0.1 2.3 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 CCD27342.1 - 0.044 14.2 0.0 0.084 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 CCD27342.1 - 0.051 13.0 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NPC1_N PF16414.5 CCD27342.1 - 0.051 13.1 0.2 0.093 12.3 0.2 1.4 1 0 0 1 1 1 0 Niemann-Pick C1 N terminus AAA_28 PF13521.6 CCD27342.1 - 0.06 13.6 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RasGEF_N PF00618.20 CCD27342.1 - 1.7 8.9 5.6 1.6 9.0 1.8 2.5 2 1 0 2 2 2 0 RasGEF N-terminal motif Hap4_Hap_bind PF10297.9 CCD27343.1 - 1.5 9.0 20.3 0.059 13.5 12.7 2.6 2 1 0 2 2 2 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 Drc1-Sld2 PF11719.8 CCD27344.1 - 1.6e-40 140.1 35.5 2.1e-40 139.7 35.5 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein NAD_binding_10 PF13460.6 CCD27345.1 - 4.1e-32 111.6 0.0 5.3e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CCD27345.1 - 0.00032 19.8 0.4 0.00052 19.1 0.4 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CCD27345.1 - 0.021 14.3 0.0 0.042 13.3 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family cobW PF02492.19 CCD27346.1 - 1e-44 152.3 0.7 1e-44 152.3 0.7 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CCD27346.1 - 0.00017 21.4 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 CCD27346.1 - 0.00023 20.7 0.9 0.3 10.6 0.0 2.7 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 CCD27346.1 - 0.0038 16.9 0.2 0.011 15.5 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 CCD27346.1 - 0.0051 16.7 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 NTPase AAA_23 PF13476.6 CCD27346.1 - 0.022 15.3 0.0 0.022 15.3 0.0 2.4 2 1 1 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 CCD27346.1 - 0.053 13.6 0.0 0.32 11.1 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCD27346.1 - 0.065 13.1 3.0 1.7 8.5 0.1 2.9 3 0 0 3 3 3 0 RsgA GTPase AAA_18 PF13238.6 CCD27346.1 - 0.1 13.1 0.2 0.35 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CCD27346.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain MeaB PF03308.16 CCD27346.1 - 0.25 10.3 0.9 1.7 7.5 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Pro_isomerase PF00160.21 CCD27347.1 - 2e-21 76.9 0.0 2.9e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Phos_pyr_kin PF08543.12 CCD27348.1 - 7.9e-08 32.0 0.0 1.3e-07 31.3 0.0 1.3 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CCD27348.1 - 0.0061 15.9 0.0 0.29 10.4 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase ANAPC4_WD40 PF12894.7 CCD27349.1 - 4.9e-06 26.7 0.0 0.023 15.0 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCD27349.1 - 0.0004 21.1 0.3 0.46 11.4 0.1 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat Forkhead PF00250.18 CCD27350.1 - 1.9e-31 108.2 1.8 1.9e-31 108.2 1.8 1.8 2 1 0 2 2 2 1 Forkhead domain MPP6 PF10175.9 CCD27351.1 - 9.7e-22 77.9 18.9 1.5e-21 77.3 18.9 1.2 1 0 0 1 1 1 1 M-phase phosphoprotein 6 CENP-B_dimeris PF09026.10 CCD27351.1 - 1.3 9.4 9.1 3 8.3 9.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Importin_rep_6 PF18829.1 CCD27351.1 - 2.3 8.4 9.8 0.5 10.5 4.5 2.3 2 1 0 2 2 2 0 Importin repeat 6 PBP1_TM PF14812.6 CCD27351.1 - 2.9 8.3 17.5 1.4 9.3 13.6 2.3 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L9_N PF01281.19 CCD27352.1 - 8e-05 22.1 0.0 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DUF1189 PF06691.11 CCD27352.1 - 0.18 11.3 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Peptidase_M76 PF09768.9 CCD27353.1 - 4.8e-72 241.3 2.3 5.8e-72 241.0 2.3 1.1 1 0 0 1 1 1 1 Peptidase M76 family DinI PF06183.13 CCD27353.1 - 0.016 15.5 0.0 0.048 14.0 0.0 1.8 1 0 0 1 1 1 0 DinI-like family DnaGprimase_HBD PF16730.5 CCD27353.1 - 0.12 12.5 0.1 0.69 10.0 0.0 2.1 2 0 0 2 2 2 0 DnaG-primase C-terminal, helicase-binding domain MBOAT PF03062.19 CCD27354.1 - 6.5e-75 252.6 39.0 8.9e-75 252.2 39.0 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CCD27354.1 - 0.0061 16.8 6.6 0.017 15.3 6.6 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family HIG_1_N PF04588.13 CCD27355.1 - 4e-05 23.7 1.6 9.3e-05 22.6 1.6 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Tim17 PF02466.19 CCD27357.1 - 1.6e-26 92.8 2.3 2.2e-26 92.4 2.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4667 PF15700.5 CCD27358.1 - 1.7e-68 231.4 42.0 1.9e-68 231.2 42.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) Dus PF01207.17 CCD27359.1 - 8e-49 166.4 0.0 1.9e-48 165.2 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) SepSecS PF05889.13 CCD27359.1 - 0.0082 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS ThiC_Rad_SAM PF01964.18 CCD27359.1 - 0.0098 14.7 0.1 0.48 9.2 0.0 2.1 1 1 1 2 2 2 2 Radical SAM ThiC family TMP-TENI PF02581.17 CCD27359.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase SPX PF03105.19 CCD27360.1 - 1.3e-42 147.1 1.0 2.8e-27 96.6 0.0 2.9 2 1 1 3 3 3 2 SPX domain CitMHS PF03600.16 CCD27360.1 - 9.6e-24 84.1 44.8 6.6e-17 61.7 17.5 2.2 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 CCD27360.1 - 6.9e-22 78.1 38.9 9.2e-22 77.7 38.9 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region AIP3 PF03915.13 CCD27360.1 - 0.12 11.4 6.8 0.047 12.8 4.0 1.6 2 0 0 2 2 2 0 Actin interacting protein 3 PRK PF00485.18 CCD27361.1 - 3.3e-64 216.3 0.0 5.6e-64 215.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 CCD27361.1 - 5.4e-33 114.2 0.1 7.8e-33 113.7 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 CCD27361.1 - 6.3e-05 23.5 0.0 0.00024 21.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CCD27361.1 - 0.00094 19.6 0.2 1.9 8.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CCD27361.1 - 0.0027 17.0 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.12 CCD27361.1 - 0.0093 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 CCD27361.1 - 0.098 12.8 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Helicase_C PF00271.31 CCD27362.1 - 2.5e-15 56.8 0.1 7e-15 55.3 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 CCD27362.1 - 3.5e-15 56.2 0.0 1.3e-14 54.4 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CCD27362.1 - 1.4e-14 54.2 0.0 3.9e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CCD27362.1 - 3.4e-07 30.2 1.9 6.6e-07 29.3 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCD27362.1 - 0.00061 20.1 0.2 0.0024 18.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCD27362.1 - 0.003 17.3 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CCD27362.1 - 0.0035 16.4 0.0 0.01 14.9 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 CCD27362.1 - 0.0063 16.9 0.1 0.014 15.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CCD27362.1 - 0.012 15.6 3.5 1.7 8.7 0.8 4.1 3 1 0 3 3 3 0 AAA domain Flavi_DEAD PF07652.14 CCD27362.1 - 0.041 13.9 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ATPase PF06745.13 CCD27362.1 - 0.098 12.0 0.5 0.49 9.7 0.1 2.1 2 0 0 2 2 2 0 KaiC Myb_DNA-bind_5 PF13873.6 CCD27362.1 - 0.13 12.4 1.0 8 6.6 0.0 3.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain fn3_6 PF17766.1 CCD27362.1 - 0.14 12.4 0.0 0.8 9.9 0.0 2.2 2 0 0 2 2 2 0 Fibronectin type-III domain ABC_tran PF00005.27 CCD27362.1 - 0.28 11.7 0.0 0.28 11.7 0.0 2.5 2 1 0 2 2 1 0 ABC transporter Glyoxalase PF00903.25 CCD27363.1 - 4.5e-37 127.1 0.1 1e-19 71.0 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CCD27363.1 - 4.7e-14 52.6 0.0 5.1e-06 26.7 0.0 3.7 1 1 3 4 4 4 4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 CCD27363.1 - 2.8e-07 30.5 0.7 0.035 14.0 0.0 4.2 4 0 0 4 4 4 2 Glyoxalase-like domain CppA_N PF14506.6 CCD27363.1 - 6.5e-06 26.2 0.2 0.065 13.3 0.0 2.4 2 0 0 2 2 2 2 CppA N-terminal Glyoxalase_6 PF18029.1 CCD27363.1 - 1.3e-05 26.0 0.0 0.025 15.4 0.0 2.8 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 CCD27363.1 - 0.0006 20.0 0.0 1.8 8.6 0.0 3.6 2 2 0 2 2 2 2 Glyoxalase-like domain DUF1338 PF07063.13 CCD27363.1 - 0.015 14.5 0.0 2.4 7.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1338) DUF3081 PF11280.8 CCD27363.1 - 0.073 12.9 0.0 2.2 8.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) Med9 PF07544.13 CCD27364.1 - 9.6e-26 89.7 0.4 2e-25 88.7 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 T4SS PF07996.11 CCD27364.1 - 9.2e-05 22.9 2.0 0.00015 22.3 1.9 1.4 1 1 0 1 1 1 1 Type IV secretion system proteins UPF0242 PF06785.11 CCD27364.1 - 0.00046 20.3 1.6 0.00063 19.9 1.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus BCNT PF07572.12 CCD27364.1 - 0.043 13.9 1.6 0.077 13.1 0.9 1.8 1 1 1 2 2 2 0 Bucentaur or craniofacial development Whi5 PF08528.11 CCD27365.1 - 1.8e-10 40.2 1.1 4.2e-10 39.0 1.1 1.7 1 0 0 1 1 1 1 Whi5 like Lipase PF00151.19 CCD27365.1 - 0.0054 16.1 1.7 0.0082 15.5 1.7 1.2 1 0 0 1 1 1 1 Lipase DUF3403 PF11883.8 CCD27365.1 - 0.14 12.3 1.5 11 6.2 0.2 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) DNA_primase_lrg PF04104.14 CCD27366.1 - 7.3e-89 297.7 0.3 1.1e-88 297.1 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit KilA-N PF04383.13 CCD27367.1 - 7.2e-06 25.8 0.1 0.00011 22.1 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain Spc42p PF11544.8 CCD27368.1 - 2.7e-11 43.3 10.9 2.7e-11 43.3 10.9 3.1 4 0 0 4 4 4 1 Spindle pole body component Spc42p DUF4083 PF13314.6 CCD27368.1 - 0.59 10.1 2.4 0.67 9.9 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) SpoIISA_toxin PF14171.6 CCD27368.1 - 4.8 6.8 6.7 0.86 9.3 2.5 1.9 2 1 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system Snf7 PF03357.21 CCD27369.1 - 3.4e-32 111.4 22.1 3.4e-32 111.4 22.1 1.9 2 0 0 2 2 2 1 Snf7 Apc13p PF05839.11 CCD27369.1 - 0.2 11.8 4.6 0.57 10.4 4.6 1.8 1 0 0 1 1 1 0 Apc13p protein RNAse_A_bac PF18431.1 CCD27369.1 - 0.21 12.6 5.7 0.41 11.6 1.2 2.6 1 1 2 3 3 3 0 Bacterial CdiA-CT RNAse A domain Rota_NS53 PF00981.17 CCD27369.1 - 2.8 6.7 8.4 1.1 8.0 5.4 1.7 1 1 1 2 2 2 0 Rotavirus RNA-binding Protein 53 (NS53) Lung_7-TM_R PF06814.13 CCD27370.1 - 3.3e-82 276.0 20.7 4.9e-82 275.5 20.7 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor Zn_clus PF00172.18 CCD27371.1 - 2e-08 34.2 13.2 2e-08 34.2 13.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ORC_WH_C PF18137.1 CCD27371.1 - 0.013 15.6 3.2 0.013 15.6 3.2 2.4 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal Rpp20 PF12328.8 CCD27371.1 - 0.015 15.2 0.6 0.05 13.6 0.6 1.8 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P zf-rbx1 PF12678.7 CCD27372.1 - 4.7e-09 36.4 4.5 8e-09 35.7 4.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CCD27372.1 - 9.6e-09 35.4 7.0 2.4e-08 34.2 7.0 1.7 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CCD27372.1 - 6.1e-07 29.3 3.4 1e-06 28.6 3.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CCD27372.1 - 2e-06 27.5 2.8 2e-06 27.5 2.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCD27372.1 - 8.5e-05 22.4 5.8 0.00016 21.4 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCD27372.1 - 0.00019 21.3 4.9 0.00049 20.1 4.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CCD27372.1 - 0.00057 19.7 4.3 0.0011 18.8 4.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CCD27372.1 - 0.0018 18.3 1.3 0.0037 17.3 1.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CCD27372.1 - 0.0043 16.7 3.2 0.011 15.3 3.2 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 CCD27372.1 - 0.0064 16.3 5.1 0.019 14.8 5.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cys_rich_CPXG PF14255.6 CCD27372.1 - 0.0098 15.8 1.1 0.026 14.4 0.1 2.1 2 0 0 2 2 2 1 Cysteine-rich CPXCG zf-RING_11 PF17123.5 CCD27372.1 - 0.014 15.1 3.2 0.014 15.1 3.2 2.7 3 0 0 3 3 3 0 RING-like zinc finger FANCL_C PF11793.8 CCD27372.1 - 0.018 15.2 2.4 0.025 14.8 1.5 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 CCD27372.1 - 0.16 12.0 2.8 0.41 10.7 2.8 1.7 1 0 0 1 1 1 0 Zinc-finger DUF5589 PF17672.1 CCD27372.1 - 8.9 6.3 6.2 0.72 9.8 0.8 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5589) HAD_2 PF13419.6 CCD27373.1 - 6.5e-20 72.0 0.0 7.9e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCD27373.1 - 5.1e-11 43.2 0.0 6e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CCD27373.1 - 0.027 14.6 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Pribosyl_synth PF14572.6 CCD27374.1 - 2.8e-41 141.6 2.1 2.1e-35 122.4 1.3 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CCD27374.1 - 1.3e-37 128.2 0.2 4.9e-37 126.4 0.0 2.0 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CCD27374.1 - 8.6e-16 57.9 0.8 3.8e-15 55.7 0.5 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CCD27374.1 - 0.068 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Phage_int_SAM_1 PF02899.17 CCD27375.1 - 0.45 10.8 3.6 7.9 6.9 0.1 3.8 5 0 0 5 5 5 0 Phage integrase, N-terminal SAM-like domain Csm1_B PF18211.1 CCD27375.1 - 0.67 9.8 4.7 0.28 11.0 0.2 2.8 3 0 0 3 3 3 0 Csm1 subunit domain B HMG_box PF00505.19 CCD27376.1 - 1.1e-32 112.2 16.7 7.9e-18 64.6 0.8 3.7 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CCD27376.1 - 3.6e-15 56.3 4.1 1.1e-09 38.8 0.5 4.3 4 2 1 5 5 5 2 HMG-box domain CHDNT PF08073.12 CCD27376.1 - 1e-11 44.6 0.1 9e-06 25.6 0.0 2.7 2 0 0 2 2 2 2 CHDNT (NUC034) domain zf-C2HE PF16278.5 CCD27377.1 - 9.3e-05 22.8 0.2 0.00041 20.7 0.2 2.2 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 CCD27377.1 - 0.00019 21.7 11.8 0.00034 20.9 2.0 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCD27377.1 - 0.00037 21.1 13.1 0.0044 17.8 2.8 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 CCD27377.1 - 0.0013 19.0 3.1 0.0028 17.9 3.1 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_aberr PF17017.5 CCD27377.1 - 0.02 15.0 4.8 0.076 13.2 3.9 2.3 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 CCD27377.1 - 0.12 12.7 3.2 0.57 10.5 3.2 2.2 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 CCD27377.1 - 2.1 8.7 8.5 8.9 6.7 1.0 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 CCD27377.1 - 6.1 7.0 9.2 3.6 7.7 3.1 2.9 1 1 1 2 2 2 0 BED zinc finger Malic_M PF03949.15 CCD27378.1 - 3.1e-85 285.5 0.0 5e-85 284.9 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CCD27378.1 - 7.8e-63 211.6 0.0 1.5e-62 210.7 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Shikimate_DH PF01488.20 CCD27378.1 - 0.047 13.8 0.1 1.3 9.1 0.0 3.1 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase TFIIE_alpha PF02002.17 CCD27379.1 - 8e-36 122.1 0.0 8e-36 122.1 0.0 2.5 3 0 0 3 3 3 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 CCD27379.1 - 1.1e-10 40.9 0.5 3.2e-10 39.4 0.5 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding PPP4R2 PF09184.11 CCD27379.1 - 0.14 11.8 20.3 0.25 10.9 20.3 1.4 1 0 0 1 1 1 0 PPP4R2 ThiF PF00899.21 CCD27380.1 - 1.7e-44 152.0 0.0 3e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CCD27380.1 - 5.3e-05 23.3 0.0 0.00011 22.3 0.0 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 CCD27380.1 - 9.3e-05 22.7 0.5 0.00093 19.5 0.5 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 CCD27380.1 - 0.004 17.4 0.1 0.0098 16.1 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 CCD27380.1 - 0.024 14.2 0.1 0.046 13.3 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 CCD27380.1 - 0.031 13.9 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Mito_carr PF00153.27 CCD27381.1 - 1e-61 204.8 2.0 8.1e-21 73.8 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CCD27381.1 - 0.01 15.1 0.4 3.1 6.9 0.0 2.9 2 1 0 2 2 2 2 Gammaproteobacterial serine protease Tim17 PF02466.19 CCD27381.1 - 0.2 12.1 4.0 9.6 6.6 0.0 3.3 1 1 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family DUF2370 PF10176.9 CCD27382.1 - 8.5e-83 277.4 0.0 1.2e-82 276.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) SNF5 PF04855.12 CCD27383.1 - 4.8e-52 177.1 4.7 4.8e-52 177.1 4.7 4.1 2 2 1 3 3 3 1 SNF5 / SMARCB1 / INI1 Cas6_N PF17952.1 CCD27383.1 - 0.15 12.4 0.7 7.6 6.9 0.1 2.8 2 0 0 2 2 2 0 Cas6 N-terminal domain Adap_comp_sub PF00928.21 CCD27384.1 - 1.5e-28 99.9 0.1 2.3e-24 86.2 0.0 2.9 2 1 0 2 2 2 2 Adaptor complexes medium subunit family Phycoerythr_ab PF02972.14 CCD27384.1 - 0.18 11.7 1.5 0.49 10.2 0.1 2.4 3 0 0 3 3 3 0 Phycoerythrin, alpha/beta chain adh_short PF00106.25 CCD27385.1 - 4.8e-82 274.1 6.2 9.6e-43 145.9 0.7 3.0 3 1 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 CCD27385.1 - 2e-68 230.5 1.1 6.9e-37 127.2 0.1 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 CCD27385.1 - 2.2e-31 108.0 0.0 4.3e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 CCD27385.1 - 2.3e-31 109.1 0.4 5.3e-15 55.8 0.1 2.3 2 0 0 2 2 2 2 KR domain Glucokinase PF02685.16 CCD27385.1 - 0.072 12.1 0.2 2.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Glucokinase PglL_A PF15864.5 CCD27385.1 - 2.3 8.0 8.0 5.6 6.8 1.0 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase QCR10 PF09796.9 CCD27386.1 - 4.9e-21 74.6 0.3 7.6e-21 73.9 0.3 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Bromodomain PF00439.25 CCD27387.1 - 1.1e-27 95.9 7.8 7.4e-18 64.4 1.0 2.6 2 0 0 2 2 2 2 Bromodomain LAMTOR PF15454.6 CCD27388.1 - 1.4e-19 70.5 7.9 1.4e-19 70.5 7.9 2.2 2 1 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator HBS1_N PF08938.10 CCD27388.1 - 0.09 13.1 0.2 0.09 13.1 0.2 2.2 2 1 0 2 2 2 0 HBS1 N-terminus Ribosomal_L50 PF10501.9 CCD27389.1 - 1.2e-28 99.4 2.4 1.2e-28 99.4 2.4 1.8 2 0 0 2 2 2 1 Ribosomal subunit 39S ABC2_membrane_3 PF12698.7 CCD27389.1 - 0.066 12.3 2.0 0.073 12.2 1.3 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Arena_ncap_C PF17290.2 CCD27391.1 - 0.03 13.7 1.0 0.06 12.7 0.2 1.9 2 0 0 2 2 2 0 Arenavirus nucleocapsid C-terminal domain FRB_dom PF08771.11 CCD27391.1 - 0.036 14.5 4.0 1.2 9.5 0.2 3.4 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain Oxysterol_BP PF01237.18 CCD27392.1 - 4.7e-84 282.4 0.1 5.1e-82 275.7 0.1 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein PAP_central PF04928.17 CCD27393.1 - 2.5e-109 364.0 0.0 3.5e-109 363.6 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CCD27393.1 - 2.1e-53 180.4 0.2 2.1e-53 180.4 0.2 1.6 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CCD27393.1 - 5.2e-14 52.3 0.0 1.6e-13 50.8 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CCD27393.1 - 0.019 15.1 0.4 0.073 13.2 0.0 2.2 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase RasGEF_N PF00618.20 CCD27393.1 - 0.26 11.5 2.7 4.3 7.6 0.1 2.7 2 0 0 2 2 2 0 RasGEF N-terminal motif Dynamin_M PF01031.20 CCD27394.1 - 4.8e-100 334.4 0.2 1.8e-99 332.6 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CCD27394.1 - 3.2e-56 190.0 0.1 2.7e-55 187.0 0.1 2.4 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 CCD27394.1 - 6.2e-28 96.8 5.2 1.6e-27 95.4 5.2 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CCD27394.1 - 0.0015 18.6 1.4 0.0067 16.5 1.4 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase PSD4 PF07631.11 CCD27394.1 - 0.11 13.0 0.6 0.98 10.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1592) AAA_16 PF13191.6 CCD27394.1 - 0.12 12.8 0.0 0.43 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain APS_kinase PF01583.20 CCD27395.1 - 9e-76 253.1 0.0 1.1e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 CCD27395.1 - 1.6e-06 28.3 0.0 4e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 CCD27395.1 - 0.00041 19.9 0.0 0.00047 19.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 CCD27395.1 - 0.0012 18.5 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CCD27395.1 - 0.0081 16.7 0.0 0.013 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCD27395.1 - 0.034 14.5 0.0 0.038 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 CCD27395.1 - 0.045 12.9 0.1 0.11 11.6 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit CbiA PF01656.23 CCD27395.1 - 0.057 13.5 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain CPT PF07931.12 CCD27395.1 - 0.099 12.5 0.3 3.8 7.3 0.0 2.4 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 CCD27395.1 - 0.11 13.0 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter PRK PF00485.18 CCD27395.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Snf7 PF03357.21 CCD27396.1 - 8.9e-31 106.8 23.1 8.9e-31 106.8 23.1 1.8 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.14 CCD27396.1 - 1.9e-06 27.9 8.5 2.4e-06 27.6 8.5 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Hpt PF01627.23 CCD27396.1 - 0.062 13.6 0.3 0.062 13.6 0.3 2.0 2 0 0 2 2 2 0 Hpt domain PDDEXK_9 PF08011.11 CCD27396.1 - 0.23 11.4 2.5 0.42 10.5 2.5 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Uds1 PF15456.6 CCD27396.1 - 2 8.6 12.5 0.071 13.3 0.7 2.4 1 1 1 2 2 2 0 Up-regulated During Septation YlqD PF11068.8 CCD27396.1 - 6.8 7.1 21.3 3.3 8.1 12.7 2.3 1 1 1 2 2 2 0 YlqD protein PITH PF06201.13 CCD27397.1 - 3.6e-35 121.4 5.8 5.2e-35 120.9 5.8 1.2 1 0 0 1 1 1 1 PITH domain COPIIcoated_ERV PF07970.12 CCD27397.1 - 6 6.6 8.2 0.34 10.7 1.1 2.2 2 1 0 2 2 2 0 Endoplasmic reticulum vesicle transporter bZIP_1 PF00170.21 CCD27398.1 - 0.0011 19.0 13.8 0.0011 19.0 13.8 2.4 2 1 0 2 2 2 1 bZIP transcription factor Glutaredoxin2_C PF04399.13 CCD27398.1 - 0.043 13.6 0.9 0.043 13.6 0.9 2.0 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain DUF722 PF05263.11 CCD27398.1 - 3 8.1 9.7 3.7 7.8 4.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF722) CUE PF02845.16 CCD27399.1 - 4.6e-12 45.4 0.1 1e-07 31.5 0.2 2.7 2 0 0 2 2 2 2 CUE domain Smr PF01713.21 CCD27399.1 - 4.3e-05 23.8 0.0 9.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Smr domain CENP-C_C PF11699.8 CCD27400.1 - 6.9e-27 93.5 2.4 1.8e-26 92.1 2.4 1.8 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 CCD27400.1 - 1e-08 36.0 1.4 1e-08 36.0 1.4 3.2 3 0 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 CCD27400.1 - 2.1e-05 24.1 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Pkinase PF00069.25 CCD27401.1 - 2.1e-72 243.7 0.0 3.5e-72 242.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD27401.1 - 4.8e-46 157.1 0.0 8.6e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CCD27401.1 - 4.9e-22 78.1 0.0 2.1e-21 76.0 0.0 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 CCD27401.1 - 5.4e-07 29.2 0.0 5.9e-05 22.5 0.0 2.7 2 1 1 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 CCD27401.1 - 5e-05 22.3 0.0 5e-05 22.3 0.0 2.5 2 1 0 2 2 2 1 Fungal protein kinase HECT PF00632.25 CCD27402.1 - 6e-71 239.4 0.1 6e-71 239.4 0.1 2.0 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) RNA_pol_Rpb2_2 PF04561.14 CCD27402.1 - 0.12 12.0 0.4 6.9 6.2 0.0 2.8 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 2 TRAM_LAG1_CLN8 PF03798.16 CCD27403.1 - 2.7e-38 131.7 25.8 2.7e-38 131.7 25.8 1.9 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CCD27403.1 - 6.4e-19 67.4 0.3 6.4e-19 67.4 0.3 2.4 2 0 0 2 2 2 1 TRAM1-like protein NST1 PF13945.6 CCD27403.1 - 0.15 12.2 0.1 0.24 11.5 0.1 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator VHS PF00790.19 CCD27404.1 - 1.2e-33 115.9 3.9 1.2e-33 115.9 3.9 1.6 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 CCD27404.1 - 8.5e-17 60.5 0.1 1.6e-16 59.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCD27404.1 - 1.1e-12 47.5 0.0 1.9e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCD27404.1 - 2.1e-09 36.9 0.0 4.4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 CCD27404.1 - 0.00045 20.5 5.4 0.00083 19.6 0.4 3.4 3 1 0 3 3 3 1 GAT domain HsbA PF12296.8 CCD27404.1 - 0.00047 20.6 0.5 0.00047 20.6 0.5 2.2 2 0 0 2 2 2 1 Hydrophobic surface binding protein A AlphaC_C PF17480.2 CCD27404.1 - 0.17 11.9 1.5 1.8 8.7 0.6 2.6 2 0 0 2 2 2 0 AlphaC C-terminal ALMT PF11744.8 CCD27404.1 - 0.34 9.7 14.1 0.21 10.4 11.7 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter Presenilin PF01080.17 CCD27404.1 - 1.8 7.2 6.1 2.9 6.5 6.1 1.3 1 0 0 1 1 1 0 Presenilin SANT_DAMP1_like PF16282.5 CCD27406.1 - 2.1e-25 88.7 2.7 2.1e-25 88.7 2.7 2.2 3 0 0 3 3 3 1 SANT/Myb-like domain of DAMP1 DMAP1_like PF17024.5 CCD27406.1 - 0.011 15.8 0.1 0.039 14.1 0.1 2.0 1 0 0 1 1 1 0 Putative DMAP1-like Phostensin_N PF13916.6 CCD27406.1 - 0.098 13.0 1.4 0.39 11.1 1.4 2.0 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal DUF572 PF04502.13 CCD27407.1 - 1.1e-45 156.8 11.7 1.3e-45 156.5 11.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Ima1_N PF09779.9 CCD27407.1 - 0.0066 17.3 3.6 0.019 15.8 0.5 2.4 1 1 1 2 2 2 1 Ima1 N-terminal domain SMC_ScpA PF02616.14 CCD27407.1 - 0.057 13.3 6.1 0.084 12.8 6.1 1.2 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Zn_ribbon_SprT PF17283.2 CCD27407.1 - 0.15 11.9 0.2 0.33 10.9 0.2 1.5 1 1 0 1 1 1 0 SprT-like zinc ribbon domain Spond_N PF06468.13 CCD27407.1 - 0.19 11.8 1.4 0.35 11.0 1.4 1.5 1 0 0 1 1 1 0 Spondin_N E6 PF00518.17 CCD27407.1 - 0.27 11.7 1.9 8.7 6.8 0.2 2.6 1 1 1 2 2 2 0 Early Protein (E6) PRP1_N PF06424.12 CCD27407.1 - 0.79 10.1 8.3 1.3 9.4 8.3 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Hydrolase_4 PF12146.8 CCD27408.1 - 3.3e-48 164.0 0.0 4e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCD27408.1 - 5.2e-19 68.9 0.0 1.3e-18 67.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCD27408.1 - 5.6e-09 36.9 0.0 6.4e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CCD27408.1 - 5.8e-05 23.0 0.0 0.13 12.0 0.0 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 CCD27408.1 - 0.0015 18.1 0.1 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 CCD27408.1 - 0.0089 15.7 0.0 0.021 14.5 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 CCD27408.1 - 0.016 14.8 0.0 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 CCD27408.1 - 0.061 12.2 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme MBR1 PF17058.5 CCD27409.1 - 1.2e-66 225.0 13.7 2e-66 224.3 13.7 1.4 1 0 0 1 1 1 1 Mitochondrial biogenesis regulation protein 1 RasGAP PF00616.19 CCD27410.1 - 1.1e-39 136.3 9.7 4.5e-37 127.8 9.7 2.9 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 CCD27410.1 - 0.00011 22.5 0.1 0.00027 21.2 0.1 1.7 1 0 0 1 1 1 1 C2 domain Pro_sub2 PF18513.1 CCD27410.1 - 0.074 13.2 5.0 1.4 9.1 0.3 3.2 2 1 1 3 3 3 0 Prodomain subtilisin 2 OTCace PF00185.24 CCD27410.1 - 0.076 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Snf7 PF03357.21 CCD27411.1 - 3e-18 66.0 8.2 3e-18 66.0 8.2 1.9 2 0 0 2 2 2 1 Snf7 MCPVI PF02993.14 CCD27411.1 - 0.00039 20.3 2.7 0.00049 20.0 2.7 1.0 1 0 0 1 1 1 1 Minor capsid protein VI Radial_spoke_3 PF06098.11 CCD27411.1 - 0.0013 18.1 0.5 0.0013 18.1 0.5 2.0 1 1 1 2 2 2 1 Radial spoke protein 3 Flu_B_M2 PF04772.12 CCD27411.1 - 0.078 13.2 1.4 0.1 12.9 0.8 1.4 1 1 0 1 1 1 0 Influenza B matrix protein 2 (BM2) LMBR1 PF04791.16 CCD27411.1 - 3 6.6 4.0 3.6 6.4 4.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Glyco_transf_22 PF03901.17 CCD27412.1 - 6.5e-33 114.6 27.6 8.3e-33 114.2 27.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Metallophos PF00149.28 CCD27413.1 - 6.8e-33 114.9 0.6 1e-32 114.3 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ubiquitin PF00240.23 CCD27414.1 - 2.4e-07 30.4 0.3 2.8e-07 30.2 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CCD27414.1 - 0.0006 19.6 0.3 0.00065 19.5 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CCD27414.1 - 0.045 14.2 0.3 0.17 12.4 0.3 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain CC2D2AN-C2 PF15625.6 CCD27414.1 - 0.061 13.1 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain Chorismate_bind PF00425.18 CCD27415.1 - 1.5e-67 227.9 0.0 2.1e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 CCD27415.1 - 2e-33 115.7 0.0 3.3e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 CCD27415.1 - 1.5e-20 73.9 0.5 4.4e-19 69.1 0.0 3.1 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 CCD27415.1 - 1.2e-08 35.0 0.0 2.2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 NAD_binding_4 PF07993.12 CCD27415.1 - 0.0033 16.6 0.1 0.0055 15.9 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein HHH_4 PF14490.6 CCD27415.1 - 0.016 15.2 0.1 2.6 8.1 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain BNR PF02012.20 CCD27415.1 - 0.035 14.1 0.4 0.25 11.5 0.1 2.7 2 0 0 2 2 2 0 BNR/Asp-box repeat Glucosamine_iso PF01182.20 CCD27416.1 - 2.6e-54 184.5 0.0 4.9e-54 183.6 0.0 1.4 2 0 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase LMBR1 PF04791.16 CCD27417.1 - 3.6e-33 115.2 38.0 6.9e-33 114.3 38.0 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF3215 PF11503.8 CCD27418.1 - 2.1e-28 98.0 0.0 2.5e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) Ribosom_S12_S23 PF00164.25 CCD27419.1 - 6.1e-33 112.8 0.7 9e-33 112.3 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S19 PF00203.21 CCD27420.1 - 6e-25 86.9 0.0 8.3e-25 86.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DEAD PF00270.29 CCD27421.1 - 3.9e-42 144.0 1.2 8.7e-42 142.9 1.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCD27421.1 - 5.6e-21 75.0 2.8 2.1e-20 73.1 0.2 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD27421.1 - 5e-10 39.7 0.2 5e-10 39.7 0.2 3.6 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 CCD27421.1 - 0.0009 19.2 0.3 0.084 12.8 0.1 2.8 2 1 0 2 2 2 1 Flavivirus DEAD domain CSF-1 PF05337.11 CCD27421.1 - 0.099 12.7 3.3 0.18 11.9 0.3 2.7 2 0 0 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) AF-4 PF05110.13 CCD27421.1 - 0.51 8.4 37.3 0.77 7.8 37.3 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein UbiA PF01040.18 CCD27424.1 - 3.8e-46 157.4 16.0 5.3e-46 157.0 16.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family MDD_C PF18376.1 CCD27425.1 - 1.8e-69 233.2 0.2 2.5e-69 232.8 0.2 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CCD27425.1 - 1.2e-09 38.3 1.4 2.3e-09 37.4 1.4 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF1819 PF08849.11 CCD27425.1 - 0.019 14.7 0.8 0.045 13.6 0.2 1.9 2 0 0 2 2 2 0 Putative inner membrane protein (DUF1819) RE_HindIII PF09518.10 CCD27425.1 - 0.054 12.7 0.1 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 HindIII restriction endonuclease WD40 PF00400.32 CCD27426.1 - 3.4e-50 166.9 13.2 1.8e-09 38.0 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 CCD27426.1 - 1e-26 93.0 10.7 1e-26 93.0 10.7 2.5 1 1 1 2 2 2 1 Tup N-terminal ANAPC4_WD40 PF12894.7 CCD27426.1 - 1.5e-16 60.5 0.3 2.6e-05 24.4 0.0 6.0 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCD27426.1 - 2.7e-05 23.0 3.4 0.82 8.2 0.0 4.4 1 1 1 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CCD27426.1 - 0.00022 20.7 0.0 0.79 9.0 0.0 3.8 2 1 2 4 4 4 3 WD40-like domain Ge1_WD40 PF16529.5 CCD27426.1 - 0.036 13.0 4.5 0.53 9.2 0.0 4.1 3 1 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ADIP PF11559.8 CCD27426.1 - 0.062 13.4 35.1 0.15 12.1 35.1 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 CCD27426.1 - 0.56 9.6 31.4 1.1 8.7 31.4 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 CCD27426.1 - 1.2 8.2 21.0 2.2 7.3 21.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 CCD27426.1 - 2.8 5.7 20.8 5.2 4.8 20.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PfUIS3 PF11567.8 CCD27427.1 - 0.0066 16.8 1.4 0.012 16.0 0.4 1.9 2 0 0 2 2 2 1 Plasmodium falciparum UIS3 membrane protein zinc_ribbon_10 PF10058.9 CCD27428.1 - 0.032 13.9 2.6 0.37 10.6 0.5 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DZR PF12773.7 CCD27428.1 - 0.21 11.6 4.7 2.8 8.1 5.3 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-P11 PF03854.14 CCD27428.1 - 8.7 6.1 6.8 11 5.7 0.0 3.4 2 1 1 3 3 3 0 P-11 zinc finger RNA_pol_Rpb2_6 PF00562.28 CCD27429.1 - 0.083 11.9 1.5 0.13 11.3 1.5 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Pkinase PF00069.25 CCD27430.1 - 1.1e-78 264.3 0.2 1.7e-78 263.6 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCD27430.1 - 3.4e-32 111.7 0.1 1.4e-30 106.4 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCD27430.1 - 3e-10 39.9 0.1 6.7e-06 25.6 0.0 2.6 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CCD27430.1 - 0.022 13.5 0.0 0.022 13.5 0.0 2.6 3 0 0 3 3 3 0 Fungal protein kinase FTA2 PF13095.6 CCD27430.1 - 0.044 13.4 0.2 0.22 11.1 0.2 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CCD27430.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0524 PF15823.5 CCD27430.1 - 0.89 8.9 5.6 0.13 11.7 0.5 2.2 2 0 0 2 2 2 0 UPF0524 of C3orf70 CDC50 PF03381.15 CCD27431.1 - 6e-92 308.1 2.6 8.3e-92 307.7 2.6 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Mso1_Sec1_bdg PF14475.6 CCD27432.1 - 3e-18 65.1 0.1 7.3e-18 63.9 0.0 1.8 2 0 0 2 2 2 1 Sec1-binding region of Mso1 HAT_KAT11 PF08214.11 CCD27433.1 - 1.9e-91 307.0 7.3 2.3e-91 306.7 7.3 1.0 1 0 0 1 1 1 1 Histone acetylation protein Ribosomal_S6 PF01250.17 CCD27434.1 - 7.5e-23 80.6 0.1 1e-22 80.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 PAP2_3 PF14378.6 CCD27435.1 - 1.7e-27 96.3 7.6 1.7e-27 96.3 7.6 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 CCD27435.1 - 3.2e-11 43.1 5.6 3.2e-11 43.1 5.6 2.5 2 0 0 2 2 2 1 PAP2 superfamily COX7C PF02935.16 CCD27435.1 - 9.8 6.5 8.8 63 3.9 4.4 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc TFIIS_M PF07500.14 CCD27436.1 - 1.4e-20 73.9 2.3 1.4e-20 73.9 2.3 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 CCD27436.1 - 3.5e-11 42.8 5.3 6.9e-11 41.9 5.3 1.5 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.13 CCD27436.1 - 3.7e-05 23.7 0.0 7.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD_Oberon PF07227.11 CCD27436.1 - 0.063 13.2 2.0 0.13 12.2 2.0 1.4 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein zf-CW PF07496.15 CCD27436.1 - 0.097 12.7 0.9 0.24 11.4 0.9 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger Prok-RING_1 PF14446.6 CCD27436.1 - 3.1 7.8 8.0 14 5.7 8.0 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 CCD27436.1 - 3.4 8.1 5.8 3.4 8.1 1.1 2.5 2 0 0 2 2 2 0 C1 domain Protamine_P2 PF00841.19 CCD27436.1 - 5 7.7 10.8 4.6 7.8 1.1 3.9 4 0 0 4 4 4 0 Sperm histone P2 EVI2A PF05399.11 CCD27436.1 - 9 5.8 20.7 5.6 6.5 9.9 2.6 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) Ribosomal_L14e PF01929.17 CCD27437.1 - 1.3e-31 108.9 0.3 1.9e-31 108.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CCD27437.1 - 8.8e-05 22.3 1.3 0.00019 21.2 1.3 1.6 1 0 0 1 1 1 1 KOW motif DUF2207 PF09972.9 CCD27438.1 - 0.023 13.5 1.5 0.024 13.4 1.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1043 PF06295.12 CCD27438.1 - 0.041 13.9 0.3 0.047 13.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Synaptobrevin PF00957.21 CCD27438.1 - 0.051 13.4 3.8 0.14 12.0 3.7 1.8 1 1 0 1 1 1 0 Synaptobrevin F-actin_cap_A PF01267.17 CCD27439.1 - 1.5e-74 250.8 2.5 1.7e-74 250.6 2.5 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Hyphal_reg_CWP PF11765.8 CCD27441.1 - 4.7e-85 285.4 17.4 4.7e-85 285.4 17.4 1.6 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal PapC_C PF13953.6 CCD27441.1 - 0.26 11.1 1.9 20 5.1 0.3 3.3 4 0 0 4 4 4 0 PapC C-terminal domain SNF2_N PF00176.23 CCD27442.1 - 2.5e-57 194.2 0.0 3.8e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 CCD27442.1 - 2.9e-48 164.4 3.4 2.7e-47 161.3 2.8 2.2 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 CCD27442.1 - 4.1e-16 59.3 0.0 1e-15 58.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCD27442.1 - 1.7e-07 31.4 0.0 5.2e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CCD27442.1 - 7.6e-06 25.3 1.2 7.9e-05 22.0 0.2 2.8 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Ran-binding PF05508.11 CCD27443.1 - 5.4e-110 367.2 4.1 5.4e-110 367.2 4.1 1.4 2 0 0 2 2 2 1 RanGTP-binding protein PRP3 PF08572.10 CCD27443.1 - 0.048 13.4 1.9 0.14 11.9 0.8 2.0 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) Copper-fist PF00649.18 CCD27444.1 - 3.5e-20 71.2 1.3 3.5e-20 71.2 1.3 2.2 1 1 1 2 2 2 1 Copper fist DNA binding domain Cullin PF00888.22 CCD27445.1 - 1e-125 420.7 33.0 1.4e-125 420.3 33.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CCD27445.1 - 3.6e-15 55.7 3.4 4.7e-15 55.4 0.9 2.7 2 0 0 2 2 2 1 Cullin protein neddylation domain YmgB PF10798.8 CCD27445.1 - 0.06 13.2 1.2 0.3 10.9 0.2 2.5 2 0 0 2 2 2 0 Biofilm development protein YmgB/AriR DUF5600 PF18150.1 CCD27445.1 - 0.11 13.1 0.8 0.75 10.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5600) Pex24p PF06398.11 CCD27446.1 - 5.9e-86 288.7 14.5 7.2e-86 288.4 14.5 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin 7TMR-DISM_7TM PF07695.11 CCD27447.1 - 0.0026 17.7 6.3 0.0035 17.3 6.3 1.1 1 0 0 1 1 1 1 7TM diverse intracellular signalling UbiA PF01040.18 CCD27447.1 - 0.0052 16.1 0.4 0.0065 15.8 0.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2556 PF10831.8 CCD27447.1 - 0.058 13.3 2.8 0.95 9.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2556) Abhydrolase_1 PF00561.20 CCD27448.1 - 1.2e-15 57.9 0.0 7.6e-15 55.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCD27448.1 - 1e-06 28.2 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCD27448.1 - 2.5e-06 28.3 0.0 3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CCD27448.1 - 9.4e-05 22.2 0.0 0.00025 20.8 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein BAAT_C PF08840.11 CCD27448.1 - 0.00054 19.9 0.0 0.00088 19.2 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 CCD27448.1 - 0.0013 18.5 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Lipase_2 PF01674.18 CCD27448.1 - 0.0052 16.3 0.0 0.0082 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 2) Esterase PF00756.20 CCD27448.1 - 0.031 13.9 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.14 CCD27448.1 - 0.053 13.0 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CCD27448.1 - 0.091 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Thioesterase PF00975.20 CCD27448.1 - 0.21 11.7 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Tmemb_9 PF05434.11 CCD27449.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.7 4 0 0 4 4 4 0 TMEM9 PALP PF00291.25 CCD27450.1 - 9.7e-66 222.2 0.0 1.1e-65 221.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 3Beta_HSD PF01073.19 CCD27451.1 - 4.3e-87 291.7 0.0 6e-87 291.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CCD27451.1 - 1.1e-24 87.3 0.0 1.4e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CCD27451.1 - 7.8e-14 51.8 0.0 3e-10 40.0 0.0 2.3 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CCD27451.1 - 3e-11 43.0 0.2 1.1e-09 37.9 0.2 2.5 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 CCD27451.1 - 9e-07 28.3 0.0 1.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CCD27451.1 - 8.8e-05 21.8 0.0 0.00029 20.1 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein N6-adenineMlase PF10237.9 CCD27452.1 - 4.3e-58 195.7 0.0 6e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase DUF4456 PF14644.6 CCD27452.1 - 0.025 14.3 0.5 0.035 13.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) IL28A PF15177.6 CCD27452.1 - 0.033 14.0 0.2 0.052 13.4 0.2 1.2 1 0 0 1 1 1 0 Interleukin-28A DnaI_N PF07319.11 CCD27452.1 - 0.11 13.2 0.7 4 8.2 0.0 2.8 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus CTP_transf_like PF01467.26 CCD27453.1 - 3.7e-31 108.2 0.0 5.5e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 CCD27453.1 - 8.4e-06 25.8 0.4 0.11 12.4 0.0 3.2 3 0 0 3 3 3 3 FAD synthetase Prp18 PF02840.15 CCD27454.1 - 8.6e-35 119.9 1.6 1.1e-34 119.5 0.2 1.9 2 1 0 2 2 2 1 Prp18 domain Mt_ATP-synt_B PF05405.14 CCD27454.1 - 0.095 12.3 2.0 0.16 11.6 1.0 1.8 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) TFIIF_beta_N PF17683.1 CCD27455.1 - 1.4e-35 122.9 8.7 1.4e-35 122.9 8.7 2.3 2 1 0 2 2 2 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 CCD27455.1 - 3.1e-27 94.5 0.6 6.6e-27 93.4 0.6 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 CCD27455.1 - 0.00088 20.1 0.1 0.00088 20.1 0.1 2.4 1 1 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Ribosomal_L38e PF01781.18 CCD27456.1 - 3.6e-27 94.3 4.7 4.1e-27 94.1 4.7 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF3600 PF12207.8 CCD27457.1 - 0.015 15.2 0.6 0.036 14.0 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) Ferrochelatase PF00762.19 CCD27458.1 - 9.6e-93 310.7 0.0 1.1e-92 310.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MBOAT PF03062.19 CCD27459.1 - 8.1e-69 232.6 16.2 1.5e-68 231.7 16.2 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF3961 PF13106.6 CCD27459.1 - 0.048 13.3 1.9 0.2 11.3 1.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Sacchrp_dh_C PF16653.5 CCD27460.1 - 2.2e-91 306.7 0.0 2.9e-91 306.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 CCD27460.1 - 5.8e-24 84.8 0.2 8.3e-24 84.3 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CCD27460.1 - 1.7e-08 34.6 0.2 3.5e-08 33.6 0.2 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 CCD27460.1 - 5.1e-08 33.0 0.6 2e-07 31.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)H-binding F420_oxidored PF03807.17 CCD27460.1 - 6.3e-05 23.5 0.1 0.00013 22.5 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 CCD27460.1 - 0.0079 15.8 0.3 0.013 15.1 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family IlvN PF07991.12 CCD27460.1 - 0.0084 15.7 0.4 0.055 13.0 0.1 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3Beta_HSD PF01073.19 CCD27460.1 - 0.01 14.8 0.1 0.018 14.0 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_3 PF03447.16 CCD27460.1 - 0.046 14.4 0.1 0.085 13.5 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 CCD27460.1 - 0.062 12.9 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DapB_N PF01113.20 CCD27460.1 - 0.1 12.7 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SIS PF01380.22 CCD27461.1 - 1.5e-68 228.7 0.1 3.6e-34 117.4 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CCD27461.1 - 1.3e-15 57.7 0.0 2.9e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CCD27461.1 - 8.9e-10 38.5 0.0 1.7e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CCD27461.1 - 5.8e-06 25.4 0.1 9.4e-06 24.7 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Peptidase_M18 PF02127.15 CCD27462.1 - 7.8e-143 476.4 0.0 1.1e-142 475.9 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Aminotran_1_2 PF00155.21 CCD27463.1 - 7.4e-65 219.5 0.0 9.2e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II NUMOD1 PF07453.13 CCD27463.1 - 0.025 14.9 0.0 0.081 13.2 0.0 1.9 1 0 0 1 1 1 0 NUMOD1 domain Spem1 PF15670.5 CCD27463.1 - 0.07 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 MFS_1 PF07690.16 CCD27464.1 - 1.8e-29 102.8 45.2 2.1e-17 63.1 25.5 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily TMEM72 PF16054.5 CCD27464.1 - 0.0061 16.3 2.3 1.1 8.9 0.2 2.8 2 0 0 2 2 2 2 Transmembrane protein family 72 Nnf1 PF03980.14 CCD27465.1 - 4.5e-28 97.8 11.3 9.4e-28 96.8 11.3 1.6 1 0 0 1 1 1 1 Nnf1 Med4 PF10018.9 CCD27465.1 - 0.0062 16.2 2.3 0.0062 16.2 2.3 2.4 3 0 0 3 3 3 1 Vitamin-D-receptor interacting Mediator subunit 4 Peptidase_M32 PF02074.15 CCD27465.1 - 0.0064 15.3 1.0 0.0064 15.3 1.0 1.8 1 1 1 2 2 2 1 Carboxypeptidase Taq (M32) metallopeptidase Apolipoprotein PF01442.18 CCD27465.1 - 0.029 14.2 1.1 0.029 14.2 1.1 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 CCD27465.1 - 0.068 13.4 1.5 0.27 11.5 0.2 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 CCD27465.1 - 0.44 9.9 5.4 0.7 9.2 5.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 CCD27465.1 - 2.5 7.9 9.9 0.2 11.5 4.2 2.2 2 1 0 2 2 2 0 Septum formation initiator FliT PF05400.13 CCD27465.1 - 5 8.0 10.2 9.7 7.1 1.8 2.9 2 1 0 2 2 2 0 Flagellar protein FliT FAM76 PF16046.5 CCD27465.1 - 8.1 5.7 11.7 8.3 5.7 10.8 1.3 1 1 0 1 1 1 0 FAM76 protein RRM_1 PF00076.22 CCD27466.1 - 0.0001 22.1 0.0 0.014 15.2 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NGP1NT PF08153.12 CCD27467.1 - 9e-50 168.2 0.4 1.7e-49 167.3 0.4 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CCD27467.1 - 6.4e-18 64.9 0.0 1.9e-13 50.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CCD27467.1 - 1.5e-05 24.5 0.0 8.9e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 CCD27467.1 - 0.00011 21.7 0.1 0.12 11.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CCD27467.1 - 0.0019 18.1 0.0 0.0047 16.8 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 CCD27467.1 - 0.0049 16.4 0.0 0.51 9.9 0.0 3.2 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CCD27467.1 - 0.014 15.4 10.2 3.3 7.8 7.7 4.1 2 1 0 2 2 2 0 Dynamin family Glyco_hydro_125 PF06824.11 CCD27467.1 - 0.031 13.2 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Metal-independent alpha-mannosidase (GH125) CAF1 PF04857.20 CCD27468.1 - 7.8e-15 54.9 0.7 6.1e-11 42.1 0.2 3.3 2 2 0 3 3 3 2 CAF1 family ribonuclease PRIMA1 PF16101.5 CCD27468.1 - 1.1 9.3 7.0 7.3 6.7 1.7 2.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 NTF2 PF02136.20 CCD27469.1 - 2.7e-14 53.8 1.7 8.6e-14 52.1 1.7 2.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Ribosomal_S28e PF01200.18 CCD27470.1 - 2.6e-32 110.6 2.5 2.8e-32 110.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e S_layer_C PF05124.12 CCD27470.1 - 0.16 11.9 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region PIN_4 PF13638.6 CCD27471.1 - 4.5e-34 117.6 0.5 4.5e-34 117.6 0.5 2.4 2 1 0 2 2 2 1 PIN domain PIN_9 PF18477.1 CCD27471.1 - 0.0026 18.0 0.1 0.2 12.0 0.0 2.8 1 1 1 2 2 2 1 PIN like domain RHD3 PF05879.12 CCD27472.1 - 1.6e-242 806.9 24.3 1.9e-242 806.7 24.3 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 CCD27472.1 - 0.00051 20.1 3.3 0.0013 18.8 0.4 2.9 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 CCD27472.1 - 0.00053 20.0 0.1 0.0021 18.1 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase DnaGprimase_HBD PF16730.5 CCD27472.1 - 0.075 13.1 0.1 0.075 13.1 0.1 3.7 4 0 0 4 4 4 0 DnaG-primase C-terminal, helicase-binding domain Roc PF08477.13 CCD27472.1 - 0.084 13.1 0.7 0.47 10.7 0.2 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase APG6_N PF17675.1 CCD27472.1 - 0.3 11.6 3.6 0.58 10.7 1.1 2.8 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF410 PF04190.13 CCD27473.1 - 6.1e-80 268.7 3.8 7.9e-80 268.3 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF2802 PF10975.8 CCD27473.1 - 0.026 14.6 0.2 0.058 13.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) NUDIX PF00293.28 CCD27474.1 - 3.3e-15 56.3 0.1 4.1e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Zn_clus PF00172.18 CCD27475.1 - 2.2e-09 37.3 9.0 5.1e-09 36.1 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Inj_translocase PF16928.5 CCD27475.1 - 1.4 8.3 18.4 0.17 11.3 11.4 2.3 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome PAT1 PF09770.9 CCD27475.1 - 2.2 6.4 25.8 0.044 12.1 10.5 2.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DcpS PF05652.12 CCD27476.1 - 3.5e-33 114.6 0.1 7.2e-33 113.5 0.1 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 CCD27476.1 - 1.5e-28 99.5 0.2 3.7e-28 98.3 0.2 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding tRNA-synt_1c PF00749.21 CCD27477.1 - 2.7e-116 387.9 0.0 4.9e-116 387.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 CCD27477.1 - 8.5e-53 178.7 2.7 1.5e-52 177.9 2.7 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 CCD27477.1 - 1.1e-29 103.5 0.9 8.4e-28 97.4 0.4 2.8 2 1 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 CCD27477.1 - 1.8e-15 57.6 6.5 5e-15 56.2 6.5 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 TetR_N PF00440.23 CCD27477.1 - 0.085 12.7 0.0 4 7.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family DAGK_cat PF00781.24 CCD27478.1 - 7e-26 90.3 0.0 1.2e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.8 CCD27478.1 - 0.024 13.4 0.3 0.16 10.7 0.0 2.2 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 Peptidase_S8 PF00082.22 CCD27479.1 - 3.4e-36 125.0 5.7 6.4e-36 124.1 5.7 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CCD27479.1 - 3.4e-13 50.1 0.4 3.4e-13 50.1 0.4 2.1 2 0 0 2 2 2 1 Peptidase inhibitor I9 PGM_PMM_I PF02878.16 CCD27480.1 - 2.7e-16 59.6 0.1 2.8e-09 36.8 0.1 2.4 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CCD27480.1 - 4.8e-09 36.3 0.1 1.3e-08 34.9 0.1 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 CCD27480.1 - 0.017 15.3 0.4 0.056 13.6 0.2 2.0 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III CAF1C_H4-bd PF12265.8 CCD27481.1 - 9.4e-24 83.5 0.9 3.5e-23 81.6 0.3 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CCD27481.1 - 2.2e-18 66.3 1.9 0.0013 19.5 0.0 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat TFIIE-A_C PF11521.8 CCD27481.1 - 7e-05 23.0 0.6 1.4 9.2 0.0 4.2 4 0 0 4 4 4 2 C-terminal general transcription factor TFIIE alpha DNA_pol_phi PF04931.13 CCD27482.1 - 4.1e-233 775.9 35.8 6.3e-233 775.2 35.8 1.3 1 0 0 1 1 1 1 DNA polymerase phi UME PF08064.13 CCD27482.1 - 0.016 15.1 0.6 0.16 11.9 0.0 3.0 3 0 0 3 3 3 0 UME (NUC010) domain Ca_bind_SSO6904 PF18249.1 CCD27482.1 - 0.025 14.9 0.2 0.27 11.6 0.3 2.8 2 0 0 2 2 2 0 Calcium binding protein SSO6904 CNOT11 PF10155.9 CCD27482.1 - 0.71 10.0 4.3 4.7 7.4 0.2 3.1 2 1 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 RNA_pol_A_CTD PF03118.15 CCD27482.1 - 8.3 6.3 9.9 0.24 11.2 0.4 3.4 4 0 0 4 4 4 0 Bacterial RNA polymerase, alpha chain C terminal domain FAM76 PF16046.5 CCD27483.1 - 2.3 7.5 16.9 3.6 6.9 16.9 1.3 1 0 0 1 1 1 0 FAM76 protein Presenilin PF01080.17 CCD27483.1 - 4.4 6.0 13.6 5.5 5.6 13.6 1.3 1 0 0 1 1 1 0 Presenilin Aconitase PF00330.20 CCD27484.1 - 1.7e-147 492.2 0.0 2.2e-147 491.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCD27484.1 - 1.1e-42 145.5 0.0 1.8e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 CCD27484.1 - 0.14 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) CRAL_TRIO_2 PF13716.6 CCD27485.1 - 6.9e-30 104.0 0.2 1.7e-29 102.7 0.2 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 CCD27485.1 - 3e-10 40.1 0.3 3e-10 40.1 0.3 1.8 2 0 0 2 2 2 1 RhoGAP domain PALP PF00291.25 CCD27486.1 - 3.4e-64 217.1 0.0 3.8e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PrpR_N PF06506.11 CCD27486.1 - 0.12 11.9 0.0 6.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Propionate catabolism activator dsrm PF00035.26 CCD27487.1 - 0.1 13.3 0.1 15 6.4 0.0 2.5 2 0 0 2 2 2 0 Double-stranded RNA binding motif Sugar_tr PF00083.24 CCD27488.1 - 2.7e-166 553.9 31.3 3.1e-166 553.7 31.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCD27488.1 - 2.4e-30 105.7 48.9 6.2e-25 87.9 25.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BaxI_1 PF12811.7 CCD27488.1 - 0.15 11.6 11.8 0.18 11.3 2.9 2.6 2 0 0 2 2 2 0 Bax inhibitor 1 like DUF1772 PF08592.11 CCD27488.1 - 8.2 6.7 12.1 16 5.8 4.1 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) G6PD_C PF02781.16 CCD27489.1 - 1.8e-94 316.2 0.0 2.4e-94 315.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CCD27489.1 - 5.7e-52 176.9 0.0 1.3e-51 175.7 0.0 1.6 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain FMN_dh PF01070.18 CCD27490.1 - 1.4e-112 376.2 0.0 1.6e-112 376.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 CCD27490.1 - 4e-06 26.2 0.0 6.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 CCD27490.1 - 0.0026 17.2 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CCD27490.1 - 0.0084 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 CCD27490.1 - 0.029 13.7 0.0 7.1 5.9 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF4912 PF16258.5 CCD27490.1 - 0.13 12.5 0.1 0.41 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4912) MFS_1 PF07690.16 CCD27491.1 - 9e-24 84.0 10.5 3.7e-23 82.0 10.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily GalKase_gal_bdg PF10509.9 CCK73391.1 - 2.2e-20 71.9 0.0 5.4e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 CCK73391.1 - 2.6e-15 56.4 0.5 4.7e-15 55.6 0.5 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CCK73391.1 - 1.1e-14 54.6 0.0 3.4e-13 49.8 0.0 2.4 2 0 0 2 2 2 1 GHMP kinases C terminal DUF1748 PF08520.10 CCK73391.1 - 8.4e-05 22.4 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Erf4 PF10256.9 CCK73392.1 - 5.8e-34 116.7 0.0 1e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Cyclin_N PF00134.23 CCK73393.1 - 5.5e-12 45.5 0.1 7.7e-12 45.1 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Sirohm_synth_C PF14823.6 CCK73393.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal RVT_1 PF00078.27 CCK73394.1 - 1.6e-33 116.1 0.1 4e-33 114.8 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CCK73394.1 - 2e-30 104.7 0.0 4.6e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCK73394.1 - 1.2e-29 102.6 0.1 3e-29 101.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CCK73394.1 - 5e-18 64.9 2.3 7.3e-18 64.4 0.6 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CCK73394.1 - 7.4e-14 52.0 0.0 1.8e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 CCK73394.1 - 2e-08 34.7 0.0 4.6e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CCK73394.1 - 1.5e-07 32.0 0.0 3.5e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CCK73394.1 - 2.2e-05 24.2 0.1 4.1e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 CCK73394.1 - 5.7e-05 23.0 2.3 0.00012 21.9 2.3 1.6 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.20 CCK73394.1 - 0.0086 16.4 0.0 0.03 14.6 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_4 PF14392.6 CCK73394.1 - 0.015 15.0 0.6 0.048 13.4 0.6 2.0 1 0 0 1 1 1 0 Zinc knuckle zf-H2C2 PF09337.10 CCK73394.1 - 0.015 15.5 0.0 0.041 14.1 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease PF09668.10 CCK73394.1 - 0.14 12.0 0.1 0.99 9.2 0.0 2.3 3 0 0 3 3 3 0 Aspartyl protease HLH PF00010.26 CCK73395.1 - 9.1e-05 22.3 1.0 0.0002 21.3 0.2 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2197 PF09963.9 CCK73395.1 - 0.12 12.7 1.3 0.18 12.0 0.6 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF1751 PF08551.10 CCK73396.1 - 5.6e-27 94.2 2.8 5.6e-27 94.2 2.8 2.2 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 CCK73396.1 - 0.39 10.7 5.6 0.87 9.6 5.6 1.6 1 1 0 1 1 1 0 Rhomboid family PTS_2-RNA PF01885.16 CCK73397.1 - 3.5e-59 199.9 0.2 4.3e-59 199.6 0.2 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.17 CCK73397.1 - 0.088 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 La domain CorA PF01544.18 CCK73398.1 - 3.7e-39 134.8 0.3 1.8e-21 76.7 0.0 2.4 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Fungal_trans PF04082.18 CCK73399.1 - 6.2e-19 68.1 4.8 6.2e-19 68.1 4.8 3.1 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCK73399.1 - 1.6e-08 34.5 13.8 2.9e-08 33.7 13.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AGH PF17558.2 CCK73399.1 - 0.1 12.7 2.3 0.26 11.5 2.3 1.6 1 0 0 1 1 1 0 Androgenic gland hormone RFC1 PF08519.12 CCK73399.1 - 2 8.6 7.0 1.5 9.0 0.0 3.8 4 1 1 5 5 5 0 Replication factor RFC1 C terminal domain DUF4644 PF15486.6 CCK73400.1 - 0.088 12.6 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) Vps23_core PF09454.10 CCK73401.1 - 2.3e-22 78.7 0.2 6e-22 77.4 0.2 1.7 1 0 0 1 1 1 1 Vps23 core domain UEV PF05743.13 CCK73401.1 - 3.2e-05 23.8 0.1 0.00012 22.0 0.0 2.0 2 0 0 2 2 2 1 UEV domain PqqD PF05402.12 CCK73401.1 - 0.038 14.3 0.2 3.6 8.0 0.0 2.8 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) ALS_ss_C PF10369.9 CCK73402.1 - 1.4e-16 60.4 0.0 6.4e-16 58.3 0.0 2.1 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 CCK73402.1 - 1.4e-13 50.3 0.1 3.2e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 CCK73402.1 - 3.3e-08 33.2 0.0 7.7e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 ACT domain Limkain-b1 PF11608.8 CCK73402.1 - 0.00034 20.6 0.0 0.0019 18.3 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 ACT_4 PF13291.6 CCK73402.1 - 0.031 14.8 0.1 0.8 10.3 0.0 2.5 2 0 0 2 2 2 0 ACT domain Cyclin_C_2 PF16899.5 CCK73402.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Cyclin C-terminal domain DUF1325 PF07039.11 CCK73403.1 - 4.8e-39 133.5 0.0 9.5e-39 132.5 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 CCK73403.1 - 7.5e-06 25.7 0.0 3.2e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 CCK73403.1 - 3.3e-05 24.3 0.1 0.024 15.1 0.0 2.6 2 0 0 2 2 2 2 Agenet domain DUF4537 PF15057.6 CCK73403.1 - 0.0074 16.3 0.0 0.064 13.3 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4537) KxDL PF10241.9 CCK73403.1 - 0.031 14.5 0.3 0.054 13.8 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein PilZ PF07238.14 CCK73403.1 - 0.055 13.8 0.0 3.2 8.1 0.0 2.9 2 1 0 2 2 2 0 PilZ domain Metal_resist PF13801.6 CCK73403.1 - 0.2 11.8 0.1 0.3 11.3 0.1 1.2 1 0 0 1 1 1 0 Heavy-metal resistance RRM_1 PF00076.22 CCK73404.1 - 1.6e-57 191.2 0.0 1.4e-19 69.7 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCK73404.1 - 2.1e-05 24.1 0.0 0.0052 16.4 0.0 2.9 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CCK73404.1 - 0.00043 20.3 0.0 1.8 8.7 0.0 3.1 3 1 0 3 3 3 2 Limkain b1 RL PF17797.1 CCK73404.1 - 0.012 15.5 0.0 3.1 7.8 0.0 2.5 2 0 0 2 2 2 0 RL domain RRM_7 PF16367.5 CCK73404.1 - 0.065 13.3 0.1 2.8 8.1 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif RRM_occluded PF16842.5 CCK73404.1 - 0.1 12.4 0.0 5.7 6.9 0.0 3.0 3 1 0 3 3 3 0 Occluded RNA-recognition motif DUF3507 PF12015.8 CCK73405.1 - 1.2e-40 139.1 0.5 2.6e-40 138.1 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Dcc1 PF09724.9 CCK73406.1 - 1.2e-89 300.9 0.5 1.4e-89 300.7 0.5 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Aminotran_5 PF00266.19 CCK73407.1 - 1.5e-97 326.9 0.3 3.2e-97 325.8 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CCK73407.1 - 5.1e-09 35.8 0.2 1.3e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CCK73407.1 - 3.7e-08 32.9 0.0 5.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CCK73407.1 - 4.1e-07 29.6 0.0 8.4e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 CCK73407.1 - 7.7e-05 21.6 0.0 0.00012 20.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Iso_dh PF00180.20 CCK73408.1 - 2.3e-124 415.1 0.0 2.6e-124 414.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DNA_ligase_aden PF01653.18 CCK73408.1 - 0.069 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain RFX_DNA_binding PF02257.15 CCK73409.1 - 3.5e-32 110.9 0.1 1e-31 109.3 0.1 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 CCK73409.1 - 0.012 16.1 0.0 0.052 14.0 0.0 2.1 1 0 0 1 1 1 0 Poxvirus D5 protein-like Cdc6_C PF09079.11 CCK73409.1 - 0.059 13.4 0.0 0.2 11.7 0.0 2.0 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain CMV_1a PF12467.8 CCK73409.1 - 1.2 9.4 5.6 0.25 11.7 0.9 2.3 2 1 0 2 2 2 0 Cucumber mosaic virus 1a protein family DnaJ_C PF01556.18 CCK73410.1 - 5.9e-37 127.0 0.2 8.6e-37 126.5 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCK73410.1 - 4.3e-24 84.4 0.7 7.1e-24 83.7 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain Methyltransf_23 PF13489.6 CCK73411.1 - 3.4e-24 85.5 0.0 4.9e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCK73411.1 - 3e-17 62.8 0.0 4.2e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCK73411.1 - 4.1e-16 59.4 0.0 7.1e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCK73411.1 - 1e-14 55.0 0.0 1.9e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCK73411.1 - 1.9e-12 47.7 0.0 6.5e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CCK73411.1 - 5.4e-08 32.6 0.0 7.7e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 CCK73411.1 - 4.3e-07 29.5 0.0 5.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CCK73411.1 - 7e-07 29.0 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 CCK73411.1 - 5e-06 26.3 0.0 1.2e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Nodulation protein S (NodS) DREV PF05219.12 CCK73411.1 - 0.00054 19.1 0.0 0.0012 18.0 0.0 1.5 1 1 0 1 1 1 1 DREV methyltransferase MetW PF07021.12 CCK73411.1 - 0.00071 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 CCK73411.1 - 0.0018 18.3 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 CCK73411.1 - 0.0076 15.8 0.0 0.11 11.9 0.0 2.3 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 CCK73411.1 - 0.01 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 CCK73411.1 - 0.029 14.3 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 CCK73411.1 - 0.031 13.7 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa tRNA-synt_1b PF00579.25 CCK73412.1 - 3.6e-20 72.5 0.0 1.1e-14 54.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Peptidase_M16_C PF05193.21 CCK73413.1 - 1.1e-16 61.4 0.1 1.1e-14 54.9 0.0 3.2 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CCK73413.1 - 2.1e-09 37.5 0.2 1e-07 32.1 0.0 3.2 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Pkinase PF00069.25 CCK73414.1 - 1.6e-61 208.0 0.1 2.7e-61 207.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCK73414.1 - 2.2e-32 112.3 0.0 3.9e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCK73414.1 - 5.6e-05 22.6 0.0 0.00035 20.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CCK73414.1 - 0.0016 17.4 3.7 0.0016 17.4 3.7 2.3 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 CCK73414.1 - 0.0025 17.5 0.4 1.3 8.6 0.1 2.7 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CCK73414.1 - 0.014 14.2 0.0 0.014 14.2 0.0 2.9 3 0 0 3 3 3 0 Fungal protein kinase Kdo PF06293.14 CCK73414.1 - 0.026 13.9 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCK73414.1 - 0.088 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 CCK73414.1 - 0.31 10.6 0.0 0.31 10.6 0.0 2.1 2 1 0 3 3 3 0 RIO1 family HlyIII PF03006.20 CCK73415.1 - 9.3e-13 48.4 24.1 1.1e-12 48.1 24.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related UvrD-helicase PF00580.21 CCK73416.1 - 1.5e-35 123.3 8.8 2.3e-17 63.5 0.7 3.4 2 2 1 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 CCK73416.1 - 2.5e-28 99.2 0.0 8.8e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.6 CCK73416.1 - 3.4e-27 95.7 0.3 3.4e-27 95.7 0.3 2.6 3 1 0 3 3 3 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 CCK73416.1 - 2.6e-11 43.7 0.0 0.00017 21.4 0.1 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 CCK73416.1 - 1.2e-09 37.8 0.0 2.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 CCK73416.1 - 3.6e-05 23.7 0.1 0.00032 20.6 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 CCK73416.1 - 0.00015 21.4 0.8 0.026 14.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain DUF1351 PF07083.11 CCK73416.1 - 0.0015 18.3 0.1 0.0056 16.5 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1351) AAA_30 PF13604.6 CCK73416.1 - 0.0029 17.4 0.0 0.34 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CCK73416.1 - 0.0064 16.5 1.6 1.1 9.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain V-ATPase_H_C PF11698.8 CCK73416.1 - 0.048 13.8 1.3 0.55 10.4 0.1 3.1 3 0 0 3 3 3 0 V-ATPase subunit H ResIII PF04851.15 CCK73416.1 - 0.071 13.1 0.8 3.8 7.5 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit BLOC1_2 PF10046.9 CCK73416.1 - 3.6 8.0 6.5 1.5 9.1 0.1 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DKCLD PF08068.12 CCK73417.1 - 5.6e-32 109.6 0.2 5.7e-31 106.4 0.4 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 CCK73417.1 - 4.4e-23 81.2 0.4 8.8e-23 80.2 0.4 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 CCK73417.1 - 1.8e-20 73.9 5.9 4.3e-19 69.3 0.0 3.8 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 CCK73417.1 - 9.7e-20 70.3 1.1 1.9e-19 69.4 1.1 1.5 1 0 0 1 1 1 1 PUA domain CDC27 PF09507.10 CCK73417.1 - 0.017 14.5 33.0 0.021 14.2 33.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 UPF0113 PF03657.13 CCK73417.1 - 0.021 15.1 0.0 0.055 13.8 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain PPP4R2 PF09184.11 CCK73417.1 - 0.2 11.2 28.2 0.28 10.7 28.2 1.1 1 0 0 1 1 1 0 PPP4R2 GAGA_bind PF06217.12 CCK73417.1 - 0.77 10.0 19.1 1.1 9.5 19.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family VIR_N PF15912.5 CCK73417.1 - 4.3 6.8 17.4 6.4 6.3 17.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal AAA_33 PF13671.6 CCK73418.1 - 1.2e-06 28.8 0.0 0.00064 19.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCK73418.1 - 9.2e-06 26.2 0.0 2.9e-05 24.6 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.6 CCK73418.1 - 1.1e-05 25.7 0.0 2.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CCK73418.1 - 0.00011 22.7 0.1 0.00048 20.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 CCK73418.1 - 0.00024 21.5 0.0 0.00038 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CCK73418.1 - 0.0005 20.5 0.0 0.002 18.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CCK73418.1 - 0.00071 19.6 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CCK73418.1 - 0.0008 19.8 0.0 0.0022 18.3 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.12 CCK73418.1 - 0.00089 18.6 0.0 0.002 17.4 0.0 1.5 2 0 0 2 2 1 1 Zeta toxin AAA_28 PF13521.6 CCK73418.1 - 0.0012 19.1 0.0 0.0021 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 CCK73418.1 - 0.0013 18.6 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_25 PF13481.6 CCK73418.1 - 0.0023 17.5 0.0 0.24 11.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CCK73418.1 - 0.0024 17.0 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein PRK PF00485.18 CCK73418.1 - 0.0026 17.5 0.0 2.9 7.6 0.0 2.7 2 1 1 3 3 3 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 CCK73418.1 - 0.0038 17.7 0.0 0.023 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 CCK73418.1 - 0.0042 16.8 0.0 0.0098 15.6 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase KTI12 PF08433.10 CCK73418.1 - 0.0046 16.4 0.0 0.0082 15.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Mg_chelatase PF01078.21 CCK73418.1 - 0.0046 16.3 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 CCK73418.1 - 0.0052 16.0 0.0 0.0097 15.1 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Rad17 PF03215.15 CCK73418.1 - 0.0054 16.7 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_7 PF12775.7 CCK73418.1 - 0.0058 16.2 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region RuvB_N PF05496.12 CCK73418.1 - 0.0062 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 CCK73418.1 - 0.0097 15.6 0.0 0.048 13.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 CCK73418.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 CCK73418.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 CCK73418.1 - 0.017 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 CCK73418.1 - 0.019 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CCK73418.1 - 0.021 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 CCK73418.1 - 0.025 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea 6PF2K PF01591.18 CCK73418.1 - 0.026 13.8 0.0 0.06 12.6 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MMR_HSR1 PF01926.23 CCK73418.1 - 0.026 14.6 0.0 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 CCK73418.1 - 0.027 14.2 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CCK73418.1 - 0.028 14.2 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 CCK73418.1 - 0.038 13.2 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 CCK73418.1 - 0.054 13.5 0.0 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 CCK73418.1 - 0.057 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Viral_helicase1 PF01443.18 CCK73418.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase dNK PF01712.19 CCK73418.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_11 PF13086.6 CCK73418.1 - 0.082 12.7 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 CCK73418.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Roc PF08477.13 CCK73418.1 - 0.093 12.9 0.0 0.34 11.1 0.0 2.0 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CCK73418.1 - 0.098 12.6 0.1 0.24 11.3 0.0 1.6 2 0 0 2 2 1 0 RsgA GTPase SRP54 PF00448.22 CCK73418.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ResIII PF04851.15 CCK73418.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ADK PF00406.22 CCK73418.1 - 0.14 12.2 0.0 0.6 10.2 0.0 1.9 2 0 0 2 2 2 0 Adenylate kinase MeaB PF03308.16 CCK73418.1 - 0.2 10.6 0.0 0.4 9.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Sigma54_activat PF00158.26 CCK73418.1 - 0.2 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF3987 PF13148.6 CCK73418.1 - 0.22 10.5 0.0 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Thioredoxin PF00085.20 CCK73419.1 - 2e-11 43.8 0.1 5.7e-11 42.3 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 CCK73419.1 - 0.00095 19.5 0.3 0.0039 17.5 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like PLDc_2 PF13091.6 CCK73420.1 - 1.2e-12 47.9 0.0 4.5e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CCK73420.1 - 3.9e-09 36.3 1.8 0.0024 18.0 0.1 2.6 2 1 0 2 2 2 2 Phospholipase D Active site motif PQ-loop PF04193.14 CCK73421.1 - 4.6e-06 26.3 8.9 4.6e-06 26.3 8.9 4.1 4 1 0 4 4 4 2 PQ loop repeat Rer1 PF03248.13 CCK73422.1 - 1.3e-72 243.1 7.4 1.4e-72 243.0 7.4 1.0 1 0 0 1 1 1 1 Rer1 family eRF1_2 PF03464.15 CCK73423.1 - 8.7e-27 94.0 0.2 1.5e-26 93.3 0.2 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CCK73423.1 - 3.2e-22 79.1 0.0 8.7e-22 77.7 0.0 1.8 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CCK73423.1 - 4e-22 78.6 0.4 6.6e-22 77.9 0.4 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L32p PF01783.23 CCK73424.1 - 4.2e-15 55.8 4.5 9e-15 54.7 4.5 1.6 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 CCK73424.1 - 0.18 11.3 2.1 0.34 10.4 2.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain RecR PF02132.15 CCK73424.1 - 0.24 11.0 0.9 0.38 10.3 0.9 1.3 1 0 0 1 1 1 0 RecR protein FMN_red PF03358.15 CCK73425.1 - 9.4e-11 41.7 0.0 1.5e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 CCK73425.1 - 0.00035 20.8 1.6 0.00061 20.0 0.1 2.2 2 2 0 2 2 2 1 Flavodoxin Flavodoxin_2 PF02525.17 CCK73425.1 - 0.001 18.8 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold Citrate_synt PF00285.21 CCK73426.1 - 9.5e-99 330.9 0.0 1.1e-98 330.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DSPc PF00782.20 CCK73427.1 - 1.1e-27 96.4 0.7 2.2e-26 92.3 0.7 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCK73427.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CCK73427.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Elf1 PF05129.13 CCK73427.1 - 0.011 15.8 0.6 3.9 7.6 0.0 3.0 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like Yippee-Mis18 PF03226.14 CCK73427.1 - 0.013 15.7 1.1 0.08 13.2 1.1 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HECT_2 PF09814.9 CCK73427.1 - 0.03 13.2 1.6 0.088 11.6 0.1 2.0 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zinc_ribbon_4 PF13717.6 CCK73427.1 - 1.5 8.9 5.1 4.9 7.2 0.8 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Apc15p PF05841.11 CCK73428.1 - 6.8e-17 62.4 0.3 6.8e-17 62.4 0.3 3.8 4 1 1 5 5 5 1 Apc15p protein AMP-binding_C_2 PF14535.6 CCK73428.1 - 0.032 14.5 0.1 0.14 12.5 0.1 2.0 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain Npa1 PF11707.8 CCK73429.1 - 1.2e-89 301.1 7.3 6.3e-89 298.7 7.3 2.4 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 CCK73429.1 - 4e-52 176.7 2.5 6.6e-52 176.0 0.1 2.7 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 IBB PF01749.20 CCK73429.1 - 0.046 14.2 1.4 0.19 12.2 1.4 2.1 1 0 0 1 1 1 0 Importin beta binding domain DUF5321 PF17254.2 CCK73430.1 - 0.0014 18.1 4.4 0.0018 17.8 0.0 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5321) PriC PF07445.12 CCK73430.1 - 0.032 14.1 0.6 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 Primosomal replication protein priC PRTP PF01366.18 CCK73430.1 - 0.054 11.5 2.0 0.23 9.5 0.7 1.8 1 1 1 2 2 2 0 Herpesvirus processing and transport protein Fungal_trans PF04082.18 CCK73431.1 - 3.5e-20 72.2 3.2 3.5e-20 72.2 3.2 3.9 4 1 0 4 4 4 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 CCK73432.1 - 1.2e-165 551.8 37.0 1.4e-165 551.6 37.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCK73432.1 - 1.3e-28 99.9 39.2 7e-28 97.6 31.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 CCK73432.1 - 0.015 13.7 5.9 0.007 14.8 3.0 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector SUR7 PF06687.12 CCK73433.1 - 5.1e-22 78.6 9.7 6.7e-22 78.2 9.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family L_HMGIC_fpl PF10242.9 CCK73433.1 - 1.4 9.1 12.2 0.27 11.4 0.6 2.5 1 1 2 3 3 3 0 Lipoma HMGIC fusion partner-like protein DUF3810 PF12725.7 CCK73433.1 - 6 6.1 5.6 12 5.2 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) AEP1 PF17049.5 CCK73434.1 - 1.4e-117 393.2 28.4 4.6e-117 391.5 28.4 1.8 1 1 0 1 1 1 1 ATPase expression protein 1 DASH_Ask1 PF08655.10 CCK73434.1 - 0.18 11.7 1.8 1.7 8.6 0.2 3.3 4 0 0 4 4 4 0 DASH complex subunit Ask1 Tht1 PF04163.12 CCK73435.1 - 8e-14 51.3 43.0 1e-12 47.7 43.0 2.0 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein DUF1640 PF07798.11 CCK73435.1 - 5e-06 26.7 11.8 2.2e-05 24.6 5.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1640) DUF2018 PF09442.10 CCK73435.1 - 0.043 14.8 3.3 0.043 14.8 3.3 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF2018) ApoLp-III PF07464.11 CCK73435.1 - 0.68 10.0 10.5 0.79 9.8 0.1 3.3 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 CCK73435.1 - 4 7.5 15.1 0.61 10.1 5.2 2.8 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SURF6 PF04935.12 CCK73436.1 - 6.2e-45 153.5 47.4 6.2e-45 153.5 47.4 4.1 2 2 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 CCK73436.1 - 5.7e-11 42.9 2.2 5.7e-11 42.9 2.2 8.4 6 4 2 8 8 8 1 60S ribosome biogenesis protein Rrp14 Motilin_ghrelin PF04644.12 CCK73436.1 - 0.36 10.6 0.1 0.36 10.6 0.1 6.1 6 1 1 7 7 7 0 Motilin/ghrelin FeoB_Cyto PF17910.1 CCK73437.1 - 0.054 14.0 1.0 40 4.8 0.0 4.0 3 0 0 3 3 3 0 FeoB cytosolic helical domain PPR_2 PF13041.6 CCK73437.1 - 0.56 10.5 2.9 4.7 7.5 0.0 3.1 3 0 0 3 3 3 0 PPR repeat family TUG-UBL1 PF11470.8 CCK73438.1 - 7.4e-22 77.3 0.4 3.3e-21 75.3 0.2 2.2 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 CCK73438.1 - 5.2e-12 45.8 0.3 2.5e-11 43.6 0.1 2.2 2 0 0 2 2 2 1 UBX domain Nop14 PF04147.12 CCK73438.1 - 0.00036 18.9 25.4 0.00036 18.9 25.4 1.8 2 0 0 2 2 2 1 Nop14-like family DNA_pol_phi PF04931.13 CCK73438.1 - 0.0024 16.1 22.2 0.004 15.3 22.2 1.4 1 0 0 1 1 1 1 DNA polymerase phi RXT2_N PF08595.11 CCK73438.1 - 0.0099 15.9 16.2 0.0099 15.9 16.2 2.6 3 0 0 3 3 3 1 RXT2-like, N-terminal LPMO_10 PF03067.15 CCK73438.1 - 0.84 10.3 5.6 4.3 8.0 5.5 2.1 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Ank_4 PF13637.6 CCK73439.1 - 5.6e-22 77.8 3.9 1.8e-08 34.8 0.7 3.5 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCK73439.1 - 6.2e-22 78.0 3.4 2.6e-09 37.6 0.2 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 CCK73439.1 - 3.6e-14 52.5 9.5 8.9e-06 25.9 0.2 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 CCK73439.1 - 1.7e-13 49.4 9.3 0.001 19.3 0.1 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 CCK73439.1 - 9.8e-08 32.1 1.0 0.00073 19.8 0.1 4.1 2 1 3 5 5 5 3 Ankyrin repeats (many copies) G-alpha PF00503.20 CCK73440.1 - 3.5e-109 365.2 12.6 5e-109 364.7 12.6 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CCK73440.1 - 1.1e-15 57.5 0.4 3.5e-10 39.6 0.0 2.8 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCK73440.1 - 0.004 16.5 0.4 0.41 10.0 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region DUF966 PF06136.13 CCK73440.1 - 0.043 13.5 6.0 0.066 12.9 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) MMR_HSR1 PF01926.23 CCK73441.1 - 9.9e-12 45.0 0.5 4.1e-11 43.0 0.1 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCK73441.1 - 0.00016 21.3 1.4 0.0005 19.7 0.7 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCK73441.1 - 0.0019 18.1 3.7 0.033 14.1 3.7 2.7 1 1 0 1 1 1 1 RsgA GTPase KTI12 PF08433.10 CCK73441.1 - 0.004 16.6 0.4 0.038 13.4 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 CCK73441.1 - 0.0068 17.0 0.5 0.029 14.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 CCK73441.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CCK73441.1 - 0.036 13.6 0.0 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CCK73441.1 - 1.5 8.8 7.2 11 6.1 0.0 3.5 3 1 1 4 4 4 0 Dynamin family Secretin_N_2 PF07655.13 CCK73441.1 - 2.9 8.5 16.8 4 8.1 7.8 2.8 2 0 0 2 2 2 0 Secretin N-terminal domain zf-Tim10_DDP PF02953.15 CCK73442.1 - 2.4e-21 75.1 2.6 3e-21 74.8 2.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger EloA-BP1 PF15870.5 CCK73442.1 - 0.093 13.0 0.2 0.12 12.7 0.2 1.1 1 0 0 1 1 1 0 ElonginA binding-protein 1 Y_phosphatase PF00102.27 CCK73443.1 - 0.088 12.4 0.8 0.17 11.4 0.8 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ydc2-catalyt PF09159.10 CCK73444.1 - 2e-15 57.3 1.0 6.9e-15 55.5 1.0 2.0 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 FF PF01846.19 CCK73445.1 - 3.9e-32 110.2 29.5 6.4e-13 48.7 2.6 6.3 5 1 1 6 6 6 4 FF domain WW PF00397.26 CCK73445.1 - 3.1e-17 62.3 5.4 1.3e-08 34.8 0.2 2.6 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 CCK73445.1 - 0.037 14.3 5.7 0.98 9.7 1.1 3.0 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain IgG_binding_B PF01378.17 CCK73445.1 - 0.047 13.8 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 B domain SAB PF04382.13 CCK73445.1 - 0.055 13.5 0.8 1.3 9.2 0.1 3.4 2 0 0 2 2 2 0 SAB domain PQQ PF01011.21 CCK73445.1 - 0.082 12.9 0.6 0.91 9.6 0.2 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat ArgJ PF01960.18 CCK73446.1 - 6.2e-144 479.4 5.6 7e-144 479.2 5.6 1.0 1 0 0 1 1 1 1 ArgJ family Suf PF05843.14 CCK73447.1 - 9.4e-56 190.0 13.0 3e-55 188.3 8.8 5.2 3 2 2 5 5 5 3 Suppressor of forked protein (Suf) TIR_2 PF13676.6 CCK73447.1 - 0.029 15.0 0.2 0.07 13.7 0.2 1.7 1 0 0 1 1 1 0 TIR domain Tom37_C PF11801.8 CCK73448.1 - 9.7e-52 174.9 0.2 1.6e-51 174.2 0.2 1.3 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.9 CCK73448.1 - 1.1e-32 113.0 1.0 2.5e-32 111.8 1.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Cu-oxidase_3 PF07732.15 CCK73450.1 - 2e-43 147.2 4.5 5.8e-40 136.0 0.5 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 CCK73450.1 - 1.9e-42 144.3 7.0 1.3e-38 131.8 0.6 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CCK73450.1 - 1.7e-35 122.5 7.7 2.5e-32 112.2 1.8 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 CCK73450.1 - 0.0055 16.8 0.4 0.55 10.4 0.0 3.5 4 0 0 4 4 4 1 Cupredoxin-like domain DUF3364 PF11844.8 CCK73450.1 - 0.033 14.4 1.7 2 8.7 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3364) C1q PF00386.21 CCK73450.1 - 0.036 14.3 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 C1q domain Glycophorin_A PF01102.18 CCK73450.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A Self-incomp_S1 PF05938.11 CCK73450.1 - 0.15 12.6 0.6 1.7 9.2 0.0 2.8 3 0 0 3 3 3 0 Plant self-incompatibility protein S1 Mito_carr PF00153.27 CCK73451.1 - 2.9e-69 229.0 5.0 2e-23 82.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 CCK73451.1 - 0.0095 15.2 0.1 0.038 13.2 0.1 1.8 2 0 0 2 2 2 1 Fuseless RabGAP-TBC PF00566.18 CCK73452.1 - 5e-32 111.3 5.0 6.9e-24 84.7 1.6 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain V_ATPase_I PF01496.19 CCK73453.1 - 3.2e-302 1004.5 0.7 3.8e-302 1004.2 0.7 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CdvA PF18822.1 CCK73453.1 - 0.28 11.0 1.7 15 5.4 0.1 3.0 4 0 0 4 4 4 0 CdvA-like coiled-coil domain SAM_KSR1 PF13543.6 CCK73453.1 - 0.53 10.4 1.8 0.98 9.6 0.6 1.9 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 DUF3450 PF11932.8 CCK73454.1 - 0.0026 17.1 3.9 0.0026 17.1 3.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.11 CCK73454.1 - 0.17 12.5 4.5 0.11 13.0 1.3 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 CCK73454.1 - 2.6 8.1 5.8 1.6 8.8 2.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) RT_RNaseH PF17917.1 CCK73455.1 - 1.1e-21 77.0 0.0 6.4e-21 74.6 0.0 2.4 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CCK73455.1 - 3.8e-16 58.9 0.0 1.9e-08 34.2 0.0 2.8 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 CCK73455.1 - 2.3e-15 56.8 0.0 8.1e-15 55.1 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CCK73455.1 - 6.2e-15 55.3 0.1 1.6e-14 53.9 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CCK73455.1 - 2.3e-08 34.0 0.9 2.3e-08 34.0 0.9 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 CCK73455.1 - 0.015 15.8 0.0 0.063 13.8 0.0 2.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.8 CCK73455.1 - 0.028 14.0 1.8 0.13 11.9 0.0 2.7 3 0 0 3 3 3 0 Ty3 transposon peptidase zf-H2C2 PF09337.10 CCK73455.1 - 0.058 13.6 0.2 0.19 12.0 0.2 2.0 1 0 0 1 1 1 0 H2C2 zinc finger Asp PF00026.23 CCK73455.1 - 0.075 12.4 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic aspartyl protease RVP PF00077.20 CCK73455.1 - 0.076 13.3 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 CCK73455.1 - 0.087 13.5 0.0 0.3 11.7 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease Vps55 PF04133.14 CCK73456.1 - 4.6e-43 145.9 10.7 5.2e-43 145.7 10.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 HSP70 PF00012.20 CCK73457.1 - 5.2e-267 886.9 15.2 5.9e-267 886.7 15.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCK73457.1 - 2.4e-15 56.2 2.8 3.4e-13 49.1 1.0 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CCK73457.1 - 0.0024 17.6 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CCK73457.1 - 0.081 13.3 10.5 1.2 9.6 0.6 4.3 3 2 0 3 3 3 0 Cell division protein FtsA YlbD_coat PF14071.6 CCK73457.1 - 0.21 11.8 7.7 0.3 11.3 6.6 1.8 1 1 0 1 1 1 0 Putative coat protein DUF5321 PF17254.2 CCK73457.1 - 0.33 10.4 7.9 0.15 11.5 2.1 3.0 3 1 1 4 4 4 0 Family of unknown function (DUF5321) DUF948 PF06103.11 CCK73457.1 - 0.86 9.9 3.3 2.1 8.7 1.6 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SpoVR PF04293.13 CCK73457.1 - 1.5 7.4 7.4 2.3 6.8 7.4 1.3 1 0 0 1 1 1 0 SpoVR like protein Atg14 PF10186.9 CCK73457.1 - 2.2 7.3 10.6 4.3 6.3 10.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Syntaxin_2 PF14523.6 CCK73457.1 - 3.1 8.2 14.1 0.48 10.8 1.5 2.6 1 1 1 2 2 2 0 Syntaxin-like protein CDT1_C PF16679.5 CCK73458.1 - 2.1e-05 24.9 1.9 5.3e-05 23.6 0.2 2.4 3 0 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain CDT1 PF08839.11 CCK73458.1 - 0.26 11.6 6.2 0.88 9.8 4.9 2.6 2 2 0 2 2 2 0 DNA replication factor CDT1 like Nucleoporin_FG PF13634.6 CCK73459.1 - 6.9e-37 126.2 290.0 2.3e-09 38.0 34.2 10.6 2 2 7 9 9 9 8 Nucleoporin FG repeat region Nucleoporin2 PF04096.14 CCK73459.1 - 1.6e-36 125.7 1.5 1.7e-36 125.6 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin autopeptidase Swi3 PF07962.12 CCK73460.1 - 3.9e-25 87.7 2.5 5.1e-25 87.3 0.7 1.9 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 Tir_receptor_C PF07489.11 CCK73460.1 - 7.6 6.4 13.1 18 5.2 13.1 1.6 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Urb2 PF10441.9 CCK73462.1 - 1.8e-58 197.9 2.1 5.3e-58 196.3 2.1 1.9 1 0 0 1 1 1 1 Urb2/Npa2 family DUF1133 PF06576.11 CCK73462.1 - 0.078 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) Voltage_CLC PF00654.20 CCK73463.1 - 2.2e-77 260.7 23.0 3.4e-77 260.1 23.0 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 CCK73463.1 - 8.8e-13 48.5 0.2 2.1e-06 28.1 0.0 2.9 3 0 0 3 3 3 2 CBS domain DUF1980 PF09323.10 CCK73463.1 - 4.7 7.1 7.8 0.78 9.6 0.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) Ribosomal_L7Ae PF01248.26 CCK73464.1 - 2.6e-26 91.2 0.1 3.2e-26 90.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CCK73464.1 - 0.0055 16.6 0.0 0.0077 16.1 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 CCK73464.1 - 0.012 15.7 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 HECT PF00632.25 CCK73466.1 - 1.3e-82 277.7 3.7 1.3e-82 277.7 3.7 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SNF2_N PF00176.23 CCK73467.1 - 5.4e-70 235.8 0.1 1.2e-69 234.7 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCK73467.1 - 2.6e-21 76.0 0.1 1.5e-20 73.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCK73467.1 - 1.1e-06 28.8 0.0 1.1e-06 28.8 0.0 3.2 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Pet191_N PF10203.9 CCK73468.1 - 3.7e-23 81.6 4.7 5.3e-23 81.1 4.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 CCK73468.1 - 0.024 14.8 1.4 0.48 10.6 0.3 2.6 2 0 0 2 2 2 0 CHCH domain CX9C PF16860.5 CCK73468.1 - 0.093 12.8 4.5 1.9 8.6 0.2 3.1 2 1 1 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Rav1p_C PF12234.8 CCK73469.1 - 1.1e-244 813.6 0.6 1.1e-244 813.6 0.6 1.6 2 0 0 2 2 2 1 RAVE protein 1 C terminal WD40 PF00400.32 CCK73469.1 - 2.3e-06 28.2 4.4 0.64 11.0 0.0 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Pro_isomerase PF00160.21 CCK73470.1 - 1.2e-43 149.2 0.1 1.8e-43 148.6 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CCK73470.1 - 1.1e-09 37.7 7.2 0.00015 21.6 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CCK73470.1 - 3.8e-07 29.6 13.0 0.0001 21.9 0.8 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CCK73470.1 - 3.3e-06 26.9 10.5 0.0034 17.5 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CCK73470.1 - 0.13 12.6 0.0 1.3 9.3 0.1 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCK73470.1 - 0.21 12.2 0.0 3.3 8.4 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat ADH_N PF08240.12 CCK73471.1 - 4.1e-26 91.0 2.9 7.6e-26 90.1 2.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCK73471.1 - 1.7e-18 66.8 0.0 3.3e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CCK73471.1 - 3.8e-06 26.4 0.2 7.5e-06 25.4 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CCK73471.1 - 0.00062 19.1 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Aldo_ket_red PF00248.21 CCK73472.1 - 6.8e-60 202.8 0.0 8.5e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sec7 PF01369.20 CCK73473.1 - 1.6e-64 217.0 3.0 4.8e-64 215.4 3.0 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CCK73473.1 - 7.8e-12 45.4 8.4 7.8e-12 45.4 8.4 3.4 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal FAST_1 PF06743.15 CCK73473.1 - 0.97 9.4 4.2 3.6 7.6 0.1 3.6 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 tRNA-synt_2 PF00152.20 CCK73474.1 - 1.3e-73 247.9 0.1 1.7e-73 247.4 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCK73474.1 - 1.7e-06 27.9 0.0 3.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PIP49_C PF12260.8 CCK73474.1 - 0.028 14.1 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Phosphodiest PF01663.22 CCK73475.1 - 2e-35 123.0 6.1 5.3e-35 121.7 6.1 1.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase SR-25 PF10500.9 CCK73475.1 - 0.00061 19.5 9.4 0.00061 19.5 9.4 3.3 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Zip PF02535.22 CCK73475.1 - 1.3 8.2 5.1 0.33 10.1 1.3 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Macoilin PF09726.9 CCK73475.1 - 8.2 4.9 13.5 1.4 7.4 8.9 2.0 2 0 0 2 2 2 0 Macoilin family Ras PF00071.22 CCK73476.1 - 1.1e-43 148.6 0.1 1.4e-43 148.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCK73476.1 - 2.2e-15 56.9 0.0 3e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCK73476.1 - 2.2e-11 43.5 0.4 2.7e-11 43.3 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCK73476.1 - 4.4e-05 23.5 0.1 7.1e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCK73476.1 - 0.00016 21.3 0.4 0.0058 16.2 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CCK73476.1 - 0.0013 18.2 0.2 0.0018 17.8 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CCK73476.1 - 0.023 13.8 0.3 3.1 6.9 0.1 2.3 1 1 0 2 2 2 0 G-protein alpha subunit AAA_14 PF13173.6 CCK73476.1 - 0.092 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PfkB PF00294.24 CCK73477.1 - 3.3e-06 26.6 0.0 4.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TENA_THI-4 PF03070.16 CCK73478.1 - 1.4e-10 41.4 1.5 1.9e-10 40.9 1.5 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family LSM PF01423.22 CCK73479.1 - 3.1e-09 36.4 0.1 4.5e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CCK73479.1 - 0.014 15.5 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF150_C PF17384.2 CCK73479.1 - 0.057 13.6 0.0 0.069 13.3 0.0 1.4 1 1 0 1 1 1 0 RimP C-terminal SH3 domain Frag1 PF10277.9 CCK73481.1 - 4.7e-33 114.6 13.1 4.7e-33 114.6 13.1 4.0 2 1 3 5 5 5 1 Frag1/DRAM/Sfk1 family SRP1_TIP1 PF00660.17 CCK73482.1 - 2.8e-33 113.9 0.0 3.3e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family DNA_pol_B_thumb PF14791.6 CCK73483.1 - 3.4e-17 62.4 0.1 3.4e-17 62.4 0.1 3.3 3 1 0 3 3 3 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 CCK73483.1 - 1.1e-14 54.6 0.0 1.3e-13 51.2 0.0 2.4 2 0 0 2 2 2 1 DNA polymerase beta palm HHH_8 PF14716.6 CCK73483.1 - 1.8e-13 50.7 0.0 7.8e-13 48.6 0.2 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 CCK73483.1 - 2.8e-11 43.1 0.1 1.2e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda BRCT_2 PF16589.5 CCK73483.1 - 0.047 14.1 0.2 0.11 12.9 0.2 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain LIN37 PF15306.6 CCK73483.1 - 0.13 12.5 1.2 0.29 11.4 1.2 1.5 1 0 0 1 1 1 0 LIN37 HHH_5 PF14520.6 CCK73483.1 - 0.14 12.8 0.0 1.6 9.4 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain SpoIIIAH PF12685.7 CCK73483.1 - 0.47 10.2 5.1 0.8 9.5 5.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein PGK PF00162.19 CCK73484.1 - 1.1e-149 498.6 0.4 1.2e-149 498.4 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase ABC2_membrane PF01061.24 CCK73485.1 - 6.3e-38 130.3 19.2 6.3e-38 130.3 19.2 2.0 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 CCK73485.1 - 1.5e-28 100.0 0.0 3.4e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter EGF_2 PF07974.13 CCK73485.1 - 0.0097 16.3 7.1 0.0097 16.3 7.1 4.5 4 0 0 4 4 4 2 EGF-like domain RsgA_GTPase PF03193.16 CCK73485.1 - 0.014 15.3 0.3 0.033 14.1 0.3 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 CCK73485.1 - 0.014 15.1 0.9 0.036 13.8 0.4 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 CCK73485.1 - 0.025 14.8 0.1 0.041 14.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CCK73485.1 - 0.037 13.8 5.4 1.4 8.6 0.3 2.9 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CCK73485.1 - 0.037 14.3 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CCK73485.1 - 0.063 13.8 1.9 0.091 13.3 0.2 2.0 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 CCK73485.1 - 0.095 12.6 0.4 0.16 11.9 0.4 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC2_membrane_3 PF12698.7 CCK73485.1 - 3.5 6.6 35.5 0.33 10.0 28.3 2.5 2 1 1 3 3 3 0 ABC-2 family transporter protein RNA_pol_Rpc34 PF05158.12 CCK73486.1 - 1.2e-104 350.4 0.1 1.3e-104 350.2 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.20 CCK73486.1 - 0.016 15.6 0.1 0.029 14.7 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator OHA PF14418.6 CCK73486.1 - 0.054 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 OST-HTH Associated domain HTH_46 PF15977.5 CCK73486.1 - 0.14 12.1 0.7 0.45 10.6 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding B-block_TFIIIC PF04182.12 CCK73486.1 - 0.4 10.9 3.3 2.8 8.2 0.1 2.4 1 1 1 2 2 2 0 B-block binding subunit of TFIIIC Gpr1_Fun34_YaaH PF01184.19 CCK73487.1 - 1.8e-90 302.1 20.5 2.1e-90 301.9 20.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family BAR PF03114.18 CCK73488.1 - 3.7e-55 187.2 1.8 4.4e-55 186.9 1.8 1.0 1 0 0 1 1 1 1 BAR domain MgtE_N PF03448.17 CCK73488.1 - 0.014 16.0 0.4 0.11 13.1 0.0 2.6 3 1 0 3 3 3 0 MgtE intracellular N domain PT-HINT PF07591.11 CCK73488.1 - 0.065 13.5 0.6 0.11 12.7 0.6 1.4 1 0 0 1 1 1 0 Pretoxin HINT domain DUF2303 PF10065.9 CCK73488.1 - 0.096 11.8 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) DUF4164 PF13747.6 CCK73488.1 - 0.2 12.0 4.5 0.58 10.5 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF5339 PF17274.2 CCK73488.1 - 0.41 11.5 2.8 0.77 10.7 1.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5339) Fib_alpha PF08702.10 CCK73488.1 - 0.64 10.2 5.4 0.25 11.6 0.8 2.4 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 CCK73489.1 - 3.6e-46 157.7 0.0 3.6e-46 157.7 0.0 3.9 4 0 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCK73489.1 - 2.2e-22 79.6 0.7 3.1e-21 75.8 0.0 2.6 2 1 1 3 3 3 1 Protein tyrosine kinase Kdo PF06293.14 CCK73489.1 - 0.0009 18.6 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SDP_N PF12278.8 CCK73489.1 - 0.011 15.8 1.6 0.011 15.8 1.6 4.3 3 2 0 3 3 3 0 Sex determination protein N terminal Kinase-like PF14531.6 CCK73489.1 - 0.025 13.9 0.1 0.082 12.2 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Choline_kinase PF01633.20 CCK73489.1 - 0.043 13.4 11.0 0.13 11.8 0.0 3.4 3 1 0 3 3 3 0 Choline/ethanolamine kinase RIO1 PF01163.22 CCK73489.1 - 0.16 11.5 0.0 0.16 11.5 0.0 2.4 4 0 0 4 4 4 0 RIO1 family TFIIA PF03153.13 CCK73490.1 - 0.0027 17.8 16.5 0.0033 17.5 16.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Rax2 PF12768.7 CCK73490.1 - 0.12 11.8 13.5 0.046 13.2 10.4 1.7 1 1 1 2 2 2 0 Cortical protein marker for cell polarity HRXXH PF13933.6 CCK73490.1 - 0.17 11.5 2.6 0.25 10.9 2.6 1.3 1 0 0 1 1 1 0 Putative peptidase family Med15 PF09606.10 CCK73490.1 - 0.57 8.8 20.8 0.72 8.5 20.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PepSY_TM PF03929.16 CCK73490.1 - 0.6 9.7 1.1 0.72 9.5 1.1 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Nrap_D5 PF17406.2 CCK73490.1 - 2.2 8.0 7.2 2.3 8.0 3.9 2.1 2 0 0 2 2 2 0 Nrap protein PAP/OAS1-like domain 5 Roughex PF06020.11 CCK73490.1 - 6.7 5.7 10.9 9.1 5.3 10.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein adh_short PF00106.25 CCK73491.1 - 1.6e-48 164.8 0.1 1.8e-48 164.6 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCK73491.1 - 5.2e-31 108.0 0.0 6.5e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCK73491.1 - 8.1e-11 42.2 0.0 1.1e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CCK73491.1 - 0.00039 20.0 0.2 0.00096 18.7 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCK73491.1 - 0.0074 15.3 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CCK73491.1 - 0.0082 15.3 0.2 0.013 14.7 0.2 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 CCK73491.1 - 0.017 14.5 0.1 0.017 14.5 0.1 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase AlaDh_PNT_N PF05222.15 CCK73492.1 - 1.1e-29 103.4 0.0 1.6e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PS_pyruv_trans PF04230.13 CCK73492.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase AlaDh_PNT_C PF01262.21 CCK73492.1 - 0.16 11.2 0.0 0.9 8.8 0.0 2.1 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Ank_4 PF13637.6 CCK73493.1 - 1.2e-09 38.5 0.4 1.1e-07 32.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCK73493.1 - 3e-08 34.1 0.0 1.1e-07 32.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.24 CCK73493.1 - 8.3e-07 29.0 3.3 1.2e-06 28.5 0.2 3.0 3 0 0 3 3 3 1 IPT/TIG domain Ank PF00023.30 CCK73493.1 - 3.3e-06 27.3 0.1 0.095 13.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CCK73493.1 - 4.5e-06 26.8 0.0 0.00018 21.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCK73493.1 - 2.1e-05 24.5 0.8 0.065 13.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat RHD_dimer PF16179.5 CCK73493.1 - 0.03 14.3 0.0 0.093 12.8 0.0 1.9 1 0 0 1 1 1 0 Rel homology dimerisation domain 7TM-7TMR_HD PF07698.11 CCK73493.1 - 0.04 13.7 0.5 0.064 13.0 0.5 1.3 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase MutS_V PF00488.21 CCK73494.1 - 8.6e-86 286.8 0.3 1.6e-85 285.9 0.3 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CCK73494.1 - 5.2e-34 118.1 0.9 5.2e-34 118.1 0.9 2.5 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 CCK73494.1 - 1.8e-20 73.6 0.2 1.3e-19 70.8 0.2 2.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 CCK73494.1 - 1.1e-18 67.3 1.8 4.3e-18 65.4 1.8 2.1 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 CCK73494.1 - 6.2e-11 42.5 0.1 4.9e-10 39.6 0.0 2.4 2 0 0 2 2 2 1 MutS domain I DUF2795 PF11387.8 CCK73495.1 - 0.097 12.9 0.1 0.31 11.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2795) DUF3310 PF11753.8 CCK73495.1 - 0.33 11.2 6.0 0.16 12.2 1.1 2.8 2 0 0 2 2 2 0 Protein of unknwon function (DUF3310) PQ-loop PF04193.14 CCK73496.1 - 3.2e-41 138.9 14.6 1.8e-22 78.8 1.2 2.9 3 0 0 3 3 3 2 PQ loop repeat Steroid_dh PF02544.16 CCK73496.1 - 0.041 13.9 0.3 0.041 13.9 0.3 2.0 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase tRNA_m1G_MT PF01746.21 CCK73497.1 - 4.2e-36 124.5 0.6 7.4e-36 123.7 0.1 1.7 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase PGC7_Stella PF15549.6 CCK73497.1 - 0.89 9.5 9.5 0.83 9.6 5.8 2.1 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain Rep_fac_C PF08542.11 CCK73498.1 - 1.4e-21 76.6 0.0 5.2e-21 74.8 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.29 CCK73498.1 - 3.4e-13 50.1 0.0 6.1e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CCK73498.1 - 4.6e-13 49.3 0.0 1.3e-10 41.3 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 CCK73498.1 - 1.4e-06 28.4 0.0 2.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCK73498.1 - 1.9e-06 28.4 0.0 0.00035 21.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CCK73498.1 - 1.4e-05 25.4 0.1 0.011 16.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 CCK73498.1 - 3e-05 23.9 0.0 5.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CCK73498.1 - 7.8e-05 22.5 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 CCK73498.1 - 0.00034 20.6 0.0 0.0011 18.9 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CCK73498.1 - 0.00057 19.7 0.0 0.0016 18.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CCK73498.1 - 0.0012 18.3 0.1 0.015 14.7 0.1 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 CCK73498.1 - 0.002 17.6 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 2 Bacterial TniB protein AAA_assoc_2 PF16193.5 CCK73498.1 - 0.0068 16.7 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 CCK73498.1 - 0.011 15.5 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit MeaB PF03308.16 CCK73498.1 - 0.014 14.4 0.0 0.058 12.4 0.0 2.0 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 CCK73498.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CCK73498.1 - 0.029 14.3 0.1 0.21 11.5 0.0 2.2 1 1 1 2 2 2 0 NTPase AAA_19 PF13245.6 CCK73498.1 - 0.034 14.5 0.1 0.14 12.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CCK73498.1 - 0.12 12.1 0.0 0.41 10.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CCK73498.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CCK73498.1 - 0.15 11.8 0.1 0.25 11.1 0.1 1.3 1 1 0 1 1 1 0 AAA domain Iso_dh PF00180.20 CCK73499.1 - 1.2e-72 245.0 0.0 1.4e-72 244.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase EF-hand_7 PF13499.6 CCK73500.1 - 4.9e-07 30.1 0.8 1.2e-06 28.9 0.8 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CCK73500.1 - 0.058 13.0 1.8 1.2 8.9 0.2 2.6 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 CCK73500.1 - 0.071 13.1 3.5 2.2 8.4 0.4 2.5 2 0 0 2 2 2 0 EF-hand domain ABC_tran PF00005.27 CCK73501.1 - 6.5e-44 149.8 0.0 6.5e-22 78.5 0.0 4.4 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 CCK73501.1 - 5.6e-27 93.6 0.0 3.2e-26 91.2 0.0 2.5 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 CCK73501.1 - 5.6e-17 62.5 1.4 0.0099 15.7 0.0 5.0 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCK73501.1 - 1.9e-15 56.9 0.0 1.7e-06 27.6 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CCK73501.1 - 5e-10 40.2 5.8 0.00056 20.5 0.1 3.4 3 0 0 3 3 3 2 AAA domain MMS19_C PF12460.8 CCK73501.1 - 5.5e-09 35.6 3.3 0.0012 18.0 0.1 3.2 2 1 1 3 3 3 3 RNAPII transcription regulator C-terminal RsgA_GTPase PF03193.16 CCK73501.1 - 1.5e-08 34.7 0.1 0.00015 21.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CCK73501.1 - 1.9e-08 33.9 0.0 0.0047 16.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CCK73501.1 - 7.3e-08 32.8 0.1 0.019 15.2 0.0 4.4 5 1 0 5 5 3 2 AAA domain MMR_HSR1 PF01926.23 CCK73501.1 - 1.5e-07 31.5 0.0 0.0021 18.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CCK73501.1 - 3.4e-07 30.5 0.0 3.3e-05 24.0 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_28 PF13521.6 CCK73501.1 - 7.8e-07 29.5 0.0 0.0087 16.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CCK73501.1 - 2.6e-06 27.9 0.9 1.2 9.5 0.0 4.5 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CCK73501.1 - 1.2e-05 25.7 0.0 0.13 12.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 CCK73501.1 - 1.8e-05 25.3 0.1 0.23 12.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain HEAT_EZ PF13513.6 CCK73501.1 - 3e-05 24.4 3.3 0.2 12.2 0.3 4.4 5 0 0 5 5 3 1 HEAT-like repeat AAA_33 PF13671.6 CCK73501.1 - 7.2e-05 23.0 0.0 0.49 10.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CCK73501.1 - 9e-05 22.9 0.3 0.31 11.4 0.0 3.4 4 0 0 4 4 3 1 AAA ATPase domain AAA_27 PF13514.6 CCK73501.1 - 0.0001 22.0 0.0 0.12 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 CCK73501.1 - 0.00013 21.1 0.2 0.36 9.8 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ParcG PF10274.9 CCK73501.1 - 0.00068 19.8 0.8 0.81 9.8 0.3 2.9 2 1 1 3 3 3 1 Parkin co-regulated protein Rad17 PF03215.15 CCK73501.1 - 0.00086 19.3 0.1 1.4 8.8 0.0 3.4 3 0 0 3 3 3 1 Rad17 P-loop domain DUF87 PF01935.17 CCK73501.1 - 0.0013 18.9 5.1 0.34 11.0 0.0 4.1 4 0 0 4 4 3 1 Helicase HerA, central domain AAA_30 PF13604.6 CCK73501.1 - 0.0015 18.3 0.3 2.7 7.7 0.1 3.5 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 CCK73501.1 - 0.0017 18.6 0.1 0.81 10.0 0.0 3.6 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 CCK73501.1 - 0.0026 17.6 6.3 0.25 11.0 0.0 3.7 5 0 0 5 5 2 2 AAA ATPase domain AAA_24 PF13479.6 CCK73501.1 - 0.0028 17.4 0.0 1.5 8.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain HEAT_2 PF13646.6 CCK73501.1 - 0.0029 18.0 1.4 0.13 12.6 0.5 3.1 1 1 2 3 3 3 2 HEAT repeats NACHT PF05729.12 CCK73501.1 - 0.0036 17.2 0.0 1.5 8.7 0.0 2.8 3 0 0 3 3 2 1 NACHT domain CLASP_N PF12348.8 CCK73501.1 - 0.005 16.4 2.5 1 8.9 0.4 2.8 1 1 1 2 2 2 1 CLASP N terminal ATPase_2 PF01637.18 CCK73501.1 - 0.006 16.5 0.1 7.5 6.4 0.0 3.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea cobW PF02492.19 CCK73501.1 - 0.0067 16.0 0.1 3.7 7.1 0.0 3.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 CCK73501.1 - 0.0071 16.1 0.0 0.29 10.9 0.0 3.0 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 CCK73501.1 - 0.0081 16.2 0.0 9.1 6.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain CLP1_P PF16575.5 CCK73501.1 - 0.013 15.3 0.0 1.5 8.6 0.0 2.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Cytidylate_kin PF02224.18 CCK73501.1 - 0.016 14.9 0.0 6.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase ATP_bind_1 PF03029.17 CCK73501.1 - 0.018 14.8 0.3 8 6.2 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UME PF08064.13 CCK73501.1 - 0.019 14.9 3.0 0.25 11.3 0.7 2.9 1 1 2 3 3 3 0 UME (NUC010) domain MOR2-PAG1_C PF14225.6 CCK73501.1 - 0.019 14.8 1.4 4.1 7.2 1.4 2.9 1 1 0 1 1 1 0 Cell morphogenesis C-terminal Roc PF08477.13 CCK73501.1 - 0.025 14.8 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Vac14_Fab1_bd PF12755.7 CCK73501.1 - 0.026 15.1 0.0 2 9.1 0.0 2.9 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region T2SSE PF00437.20 CCK73501.1 - 0.032 13.3 0.1 0.53 9.3 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein MutS_V PF00488.21 CCK73501.1 - 0.035 14.1 0.1 5.3 7.0 0.1 2.5 2 0 0 2 2 2 0 MutS domain V Septin PF00735.18 CCK73501.1 - 0.036 13.4 0.0 2.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Septin Adaptin_N PF01602.20 CCK73501.1 - 0.036 12.6 4.9 0.096 11.2 4.9 1.7 1 1 0 1 1 1 0 Adaptin N terminal region IstB_IS21 PF01695.17 CCK73501.1 - 0.036 13.8 0.1 16 5.2 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 CCK73501.1 - 0.044 13.3 0.0 6.6 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region HEAT PF02985.22 CCK73501.1 - 0.048 13.9 1.7 63 4.2 0.0 4.8 5 0 0 5 5 3 0 HEAT repeat NTPase_1 PF03266.15 CCK73501.1 - 0.057 13.3 0.0 14 5.6 0.1 2.8 2 0 0 2 2 2 0 NTPase G-alpha PF00503.20 CCK73501.1 - 0.076 12.2 0.0 4.1 6.5 0.0 2.5 2 0 0 2 2 2 0 G-protein alpha subunit Mg_chelatase PF01078.21 CCK73501.1 - 0.076 12.4 0.0 1.5 8.2 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Ploopntkinase3 PF18751.1 CCK73501.1 - 0.098 12.6 0.0 21 5.0 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF3385 PF11865.8 CCK73501.1 - 0.098 12.6 0.6 11 5.9 0.5 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3385) GTP_EFTU PF00009.27 CCK73501.1 - 0.1 12.1 0.0 13 5.3 0.0 2.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF3437 PF11919.8 CCK73501.1 - 0.12 12.3 0.7 0.48 10.4 0.1 2.5 2 0 0 2 2 1 0 Domain of unknown function (DUF3437) ATP-synt_ab PF00006.25 CCK73501.1 - 0.15 11.7 0.4 7.8 6.1 0.1 3.1 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 CCK73501.1 - 0.25 11.8 2.3 24 5.4 0.5 3.6 2 1 0 2 2 2 0 AAA domain NUC173 PF08161.12 CCK73501.1 - 0.3 10.7 2.0 3.3 7.3 0.3 2.4 1 1 1 2 2 2 0 NUC173 domain MukB PF04310.12 CCK73501.1 - 0.57 9.9 1.8 34 4.1 0.1 2.9 3 0 0 3 3 2 0 MukB N-terminal AAA_13 PF13166.6 CCK73501.1 - 2.5 6.6 14.7 2 7.0 0.0 4.4 4 1 0 5 5 5 0 AAA domain Pkinase PF00069.25 CCK73502.1 - 2.2e-57 194.4 0.0 1.4e-53 181.9 0.0 2.8 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCK73502.1 - 4.1e-23 82.0 0.0 5.9e-19 68.4 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCK73502.1 - 0.00017 21.0 0.7 0.27 10.5 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 CCK73502.1 - 0.00027 20.3 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CCK73502.1 - 0.0069 16.0 1.0 0.092 12.4 0.2 2.4 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 SNF2_N PF00176.23 CCK73503.1 - 4.2e-51 173.7 0.1 1.4e-50 172.0 0.1 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 CCK73503.1 - 1.7e-09 37.8 12.3 4.1e-09 36.6 12.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CCK73503.1 - 4.7e-09 35.9 12.6 1e-08 34.9 12.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CCK73503.1 - 2.3e-08 33.7 9.8 4.7e-08 32.8 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCK73503.1 - 2e-06 27.6 12.0 5.2e-06 26.2 12.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCK73503.1 - 5.1e-06 26.4 5.3 5.1e-06 26.4 5.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CCK73503.1 - 2.6e-05 24.1 12.5 7e-05 22.7 12.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CCK73503.1 - 4.1e-05 23.8 8.0 0.00017 21.8 8.0 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CCK73503.1 - 8e-05 22.4 8.3 0.0002 21.2 8.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CCK73503.1 - 0.0017 18.5 11.6 0.0044 17.1 11.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 CCK73503.1 - 0.084 12.6 9.6 0.27 11.0 9.6 2.0 1 0 0 1 1 1 0 RING-like zinc finger Helicase_C PF00271.31 CCK73503.1 - 0.091 13.1 0.0 0.7 10.3 0.0 2.6 2 0 0 2 2 2 0 Helicase conserved C-terminal domain zf-ANAPC11 PF12861.7 CCK73503.1 - 0.15 12.1 5.0 0.4 10.8 5.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MetOD2 PF18548.1 CCK73503.1 - 0.23 11.6 4.3 0.19 11.9 0.4 3.0 2 0 0 2 2 2 0 Metanogen output domain 2 Rx_N PF18052.1 CCK73503.1 - 0.32 11.3 3.0 12 6.2 0.0 3.8 4 0 0 4 4 2 0 Rx N-terminal domain zf-RING_6 PF14835.6 CCK73503.1 - 0.38 10.7 10.8 0.091 12.6 5.4 2.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CCK73503.1 - 1.2 9.3 7.3 2.5 8.3 5.1 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 CCK73503.1 - 6.8 6.4 9.7 15 5.3 9.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Clat_adaptor_s PF01217.20 CCK73504.1 - 6.4e-54 181.8 0.8 7.3e-54 181.6 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TP_methylase PF00590.20 CCK73505.1 - 2.9e-26 92.7 0.0 4.1e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PI_PP_I PF18363.1 CCK73506.1 - 0.99 9.6 3.7 1.7 8.9 0.8 2.8 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain Pmp3 PF01679.17 CCK73507.1 - 7.2e-18 64.5 46.7 2.3e-07 30.9 8.4 4.3 4 0 0 4 4 4 4 Proteolipid membrane potential modulator DUF3341 PF11821.8 CCK73507.1 - 0.084 12.5 0.1 0.4 10.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) ABC1 PF03109.16 CCK73508.1 - 4.2e-30 104.4 0.0 7.7e-30 103.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CCK73508.1 - 7e-05 22.5 0.0 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Zn_clus PF00172.18 CCK73509.1 - 6e-08 32.7 8.4 1.1e-07 31.8 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CCK73509.1 - 1.9e-06 27.1 10.9 1.1e-05 24.6 10.9 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain PheRS_DBD2 PF18554.1 CCK73509.1 - 0.061 13.3 0.3 0.19 11.8 0.3 1.9 1 0 0 1 1 1 0 PheRS DNA binding domain 2 CC190 PF15768.5 CCK73510.1 - 0.053 13.6 1.5 0.067 13.3 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 190 FliJ PF02050.16 CCK73511.1 - 0.007 16.6 7.8 0.009 16.2 7.3 1.5 1 1 0 1 1 1 1 Flagellar FliJ protein DUF3450 PF11932.8 CCK73511.1 - 0.015 14.6 11.7 0.19 11.0 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 CCK73511.1 - 0.017 15.6 9.8 0.023 15.2 9.8 1.2 1 0 0 1 1 1 0 Fez1 Tropomyosin PF00261.20 CCK73511.1 - 0.022 14.1 19.5 0.033 13.6 19.5 1.2 1 0 0 1 1 1 0 Tropomyosin DUF4407 PF14362.6 CCK73511.1 - 0.1 11.9 3.2 0.13 11.6 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C4H2 PF10146.9 CCK73511.1 - 0.12 12.7 7.5 0.17 12.2 7.5 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Tropomyosin_1 PF12718.7 CCK73511.1 - 0.14 12.3 19.9 0.22 11.7 19.9 1.3 1 0 0 1 1 1 0 Tropomyosin like Spc7 PF08317.11 CCK73511.1 - 0.16 10.8 20.0 0.13 11.1 18.9 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein PspA_IM30 PF04012.12 CCK73511.1 - 0.16 11.5 10.2 0.064 12.8 3.1 2.7 1 1 2 3 3 3 0 PspA/IM30 family DUF2730 PF10805.8 CCK73511.1 - 0.23 11.5 11.0 2.1 8.5 6.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) ADIP PF11559.8 CCK73511.1 - 0.24 11.5 14.9 0.12 12.4 10.7 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Exonuc_VII_L PF02601.15 CCK73511.1 - 0.25 10.9 6.8 0.33 10.5 6.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF745 PF05335.13 CCK73511.1 - 0.74 9.5 5.0 0.41 10.4 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) SlyX PF04102.12 CCK73511.1 - 0.79 10.4 12.6 0.47 11.1 6.0 2.9 1 1 2 3 3 3 0 SlyX FAM76 PF16046.5 CCK73511.1 - 0.91 8.8 9.2 1.4 8.2 9.2 1.3 1 0 0 1 1 1 0 FAM76 protein BST2 PF16716.5 CCK73511.1 - 1.5 9.4 13.6 0.45 11.1 8.4 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Jnk-SapK_ap_N PF09744.9 CCK73511.1 - 1.6 8.9 18.4 7.6 6.7 18.4 1.9 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Syntaxin-6_N PF09177.11 CCK73511.1 - 3.1 8.4 10.0 3.8 8.1 8.5 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ACCA PF03255.14 CCK73511.1 - 3.4 7.5 10.5 0.3 11.0 4.1 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit HIP1_clath_bdg PF16515.5 CCK73511.1 - 4.5 7.9 17.1 2.2 8.9 5.0 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Glycogen_syn PF05693.13 CCK73512.1 - 0 1137.3 0.0 0 1137.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 CCK73512.1 - 1.1e-08 34.8 0.0 1.3e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCK73512.1 - 3.3e-07 30.8 0.0 0.0017 18.8 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCK73512.1 - 0.00018 21.6 0.1 0.00042 20.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CCK73512.1 - 0.00035 21.1 0.0 0.00079 19.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 CCK73512.1 - 0.00095 18.9 0.1 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Phage_hub_GP28 PF11110.8 CCK73512.1 - 0.1 12.5 0.5 0.54 10.2 0.1 2.2 3 0 0 3 3 3 0 Baseplate hub distal subunit Pkinase PF00069.25 CCK73513.1 - 5.2e-71 239.1 0.0 7.9e-71 238.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCK73513.1 - 2.2e-39 135.3 0.0 3.5e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCK73513.1 - 0.00048 19.5 0.1 0.06 12.6 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CCK73513.1 - 0.0024 16.7 0.0 0.0054 15.6 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CCK73513.1 - 0.042 12.8 0.1 0.085 11.8 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 CCK73513.1 - 0.08 12.4 0.4 0.19 11.2 0.1 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.14 CCK73513.1 - 0.099 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WHIM1 PF15612.6 CCK73514.1 - 0.00034 20.1 0.1 0.0009 18.7 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 SNARE PF05739.19 CCK73515.1 - 2.2e-16 59.6 0.3 4.1e-16 58.7 0.3 1.5 1 0 0 1 1 1 1 SNARE domain AAA_17 PF13207.6 CCK73515.1 - 0.15 12.5 1.0 0.25 11.8 0.2 1.8 2 0 0 2 2 2 0 AAA domain SUR7 PF06687.12 CCK73516.1 - 7.1e-19 68.3 20.9 1.4e-18 67.4 20.9 1.4 1 0 0 1 1 1 1 SUR7/PalI family CitMHS PF03600.16 CCK73516.1 - 0.0012 18.1 0.5 0.0065 15.7 0.0 1.9 2 0 0 2 2 2 1 Citrate transporter Fig1 PF12351.8 CCK73516.1 - 0.22 11.4 7.2 0.29 11.0 6.0 1.9 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 WD40 PF00400.32 CCK73517.1 - 1.1e-32 111.6 10.8 3.8e-08 33.8 0.6 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 CCK73517.1 - 9.2e-09 34.5 6.8 4.3e-06 25.7 0.2 4.7 1 1 3 5 5 5 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CCK73517.1 - 4.3e-08 33.3 0.3 0.022 15.0 0.0 5.1 6 0 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Caf4 PF11615.8 CCK73517.1 - 0.0052 16.7 0.1 1.7 8.6 0.0 2.6 2 0 0 2 2 2 1 CCR4-associated factor 4 WD40_like PF17005.5 CCK73517.1 - 0.0065 15.8 0.4 0.027 13.8 0.1 2.2 3 0 0 3 3 3 1 WD40-like domain Osmo_CC PF08946.10 CCK73517.1 - 0.08 13.2 0.3 1.1 9.6 0.1 2.7 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF5046 PF16465.5 CCK73517.1 - 0.12 11.8 0.7 2.5 7.5 0.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5046) Noelin-1 PF12308.8 CCK73517.1 - 0.7 9.9 2.5 7.9 6.5 0.1 2.8 2 0 0 2 2 2 0 Neurogenesis glycoprotein DUF16 PF01519.16 CCK73517.1 - 1.3 9.6 5.4 0.73 10.4 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 GATA PF00320.27 CCK73518.1 - 4e-13 48.7 4.1 4e-13 48.7 4.1 2.2 2 0 0 2 2 2 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 CCK73518.1 - 0.0058 16.1 0.2 0.017 14.6 0.2 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding BP28CT PF08146.12 CCK73519.1 - 1.9e-36 125.3 4.9 1.9e-36 125.3 4.9 3.7 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 CCK73519.1 - 8.6e-20 71.2 2.1 8.6e-20 71.2 2.1 5.6 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 CCK73519.1 - 0.00023 21.5 0.1 1.6 9.2 0.0 4.8 4 0 0 4 4 4 1 HEAT repeats LuxT_C PF18285.1 CCK73519.1 - 0.009 16.5 10.1 7 7.3 0.4 5.1 6 0 0 6 6 6 2 Tetracycline repressor LuxT C-terminal domain EntA_Immun PF08951.10 CCK73519.1 - 0.026 14.9 2.0 0.49 10.8 0.1 4.4 4 0 0 4 4 4 0 Enterocin A Immunity HEAT PF02985.22 CCK73519.1 - 0.031 14.5 2.3 8.6 6.9 0.1 4.5 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 CCK73519.1 - 0.033 14.7 0.0 6.6 7.4 0.0 3.3 3 0 0 3 3 3 0 HEAT-like repeat CLASP_N PF12348.8 CCK73519.1 - 0.046 13.3 0.1 0.046 13.3 0.1 4.0 4 0 0 4 4 4 0 CLASP N terminal Pkinase PF00069.25 CCK73520.1 - 1.6e-49 168.6 0.0 5.9e-48 163.5 0.0 2.4 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCK73520.1 - 2.9e-24 85.8 0.1 1.5e-22 80.1 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase SET PF00856.28 CCK73521.1 - 9.6e-06 26.1 5.6 9.6e-06 26.1 5.6 2.6 2 1 0 2 2 2 1 SET domain Stc1 PF12898.7 CCK73521.1 - 0.01 16.3 7.5 0.01 16.3 7.5 3.2 3 0 0 3 3 3 0 Stc1 domain PHD PF00628.29 CCK73521.1 - 2.9 7.9 21.6 0.11 12.3 12.6 2.9 2 1 1 3 3 3 0 PHD-finger SLM4 PF16818.5 CCK73521.1 - 3.2 7.7 11.5 0.089 12.8 4.5 2.0 2 0 0 2 2 2 0 Protein SLM4 Prok-RING_1 PF14446.6 CCK73521.1 - 6.6 6.7 10.4 1.3 9.0 2.4 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 CCK73521.1 - 9.8 6.4 14.7 2.1 8.5 9.2 2.9 2 1 0 2 2 2 0 PHD-finger Pam16 PF03656.13 CCK73522.1 - 4.1e-50 169.1 3.5 4.9e-50 168.8 3.5 1.2 1 0 0 1 1 1 1 Pam16 MLD PF11647.8 CCK73522.1 - 0.026 14.8 0.1 0.07 13.4 0.1 1.7 1 0 0 1 1 1 0 Membrane Localization Domain DUF4834 PF16118.5 CCK73522.1 - 0.6 11.1 4.7 10 7.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Zn_clus PF00172.18 CCK73523.1 - 6.8e-06 26.1 9.3 6.8e-06 26.1 9.3 2.2 2 1 1 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 CCK73523.1 - 0.012 15.6 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 PAS fold GTP_EFTU PF00009.27 CCK73524.1 - 3.1e-61 206.3 0.0 4.9e-61 205.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CCK73524.1 - 6.1e-25 87.1 0.0 1.6e-24 85.7 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CCK73524.1 - 2.8e-15 56.1 0.0 2.3e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCK73524.1 - 5.6e-08 33.1 1.0 4e-07 30.3 1.1 2.4 1 1 1 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CCK73524.1 - 0.00015 21.6 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CCK73524.1 - 0.00039 20.5 0.0 0.0011 19.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CCK73524.1 - 0.0032 16.8 0.5 0.12 11.6 0.0 3.0 3 0 0 3 3 3 1 AIG1 family AvrPtoB_bdg PF16847.5 CCK73524.1 - 0.039 14.4 0.1 2.5 8.7 0.0 3.3 3 0 0 3 3 3 0 Avirulence AvrPtoB, BAK1-binding domain PI3_PI4_kinase PF00454.27 CCK73525.1 - 1.8e-55 188.5 0.0 3.3e-55 187.6 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ChAPs PF09295.10 CCK73526.1 - 2.2e-43 148.8 4.9 3.9e-36 124.9 1.6 2.3 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 CCK73526.1 - 9.7e-05 22.2 0.6 0.031 14.4 0.3 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CCK73526.1 - 0.00013 22.1 0.6 0.00035 20.8 0.6 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CCK73526.1 - 0.0021 17.8 0.7 0.017 14.9 0.4 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CCK73526.1 - 0.0067 17.0 0.0 0.014 16.1 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 CCK73526.1 - 0.01 16.2 0.1 0.1 13.0 0.1 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CCK73526.1 - 0.017 15.6 0.0 0.017 15.6 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCK73526.1 - 0.079 13.3 0.3 0.41 11.0 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CCK73526.1 - 0.11 12.7 3.4 5.2 7.5 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCK73526.1 - 0.22 11.6 0.6 0.88 9.7 0.1 2.3 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF4758 PF15950.5 CCK73526.1 - 1.5 9.2 5.7 3.6 7.9 5.7 1.6 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein SAPS PF04499.15 CCK73527.1 - 5e-172 573.1 3.1 5e-172 573.1 3.1 2.5 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein Arm PF00514.23 CCK73527.1 - 0.007 16.4 0.0 0.044 13.9 0.0 2.4 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat PTPLA PF04387.14 CCK73528.1 - 3.4e-52 176.5 10.8 5.1e-52 175.9 10.8 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Ribosomal_L21p PF00829.21 CCK73529.1 - 2.2e-11 43.9 0.4 2.8e-11 43.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.25 CCK73530.1 - 6.9e-65 219.0 0.0 1.3e-64 218.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCK73530.1 - 5.4e-44 150.4 0.0 9.6e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCK73530.1 - 5.9e-11 42.2 0.0 6.8e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CCK73530.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Na_H_Exchanger PF00999.21 CCK73531.1 - 9.4e-55 185.9 35.3 1.4e-54 185.4 35.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family EHD_N PF16880.5 CCK73531.1 - 0.044 13.7 0.4 0.11 12.4 0.4 1.6 1 0 0 1 1 1 0 N-terminal EH-domain containing protein Ion_trans_2 PF07885.16 CCK73532.1 - 2.5e-27 94.6 30.5 6.8e-15 54.8 9.5 3.5 3 0 0 3 3 3 2 Ion channel VIT1 PF01988.19 CCK73532.1 - 0.87 9.4 4.7 0.7 9.7 0.2 2.8 3 0 0 3 3 3 0 VIT family DUF21 PF01595.20 CCK73532.1 - 3.4 7.3 12.2 0.2 11.3 3.4 2.7 2 1 0 3 3 3 0 Cyclin M transmembrane N-terminal domain UvrD-helicase PF00580.21 CCK73533.1 - 2.2e-63 214.7 0.3 2.2e-63 214.7 0.3 3.7 5 1 0 5 5 5 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CCK73533.1 - 5.8e-42 144.3 0.1 5.8e-42 144.3 0.1 2.8 3 1 0 3 3 3 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CCK73533.1 - 1.8e-28 99.7 0.1 7.5e-28 97.7 0.0 2.1 3 0 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.6 CCK73533.1 - 5.3e-08 32.6 0.3 0.00034 20.4 0.0 2.5 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 CCK73533.1 - 0.0048 16.6 0.0 0.19 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 CCK73533.1 - 0.14 12.0 0.2 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Helicase DUF2407 PF10302.9 CCK73533.1 - 1.5 9.4 6.2 4.5 7.9 0.0 3.5 3 0 0 3 3 3 0 DUF2407 ubiquitin-like domain GWT1 PF06423.12 CCK73534.1 - 9.9e-38 129.6 5.3 9.9e-38 129.6 5.3 2.7 3 1 0 3 3 3 1 GWT1 BRCT PF00533.26 CCK73535.1 - 3.2e-16 59.4 5.8 1.3e-06 28.7 0.1 5.2 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CCK73535.1 - 1.8e-12 47.0 0.1 7.4e-06 25.8 0.0 3.6 3 0 0 3 3 3 3 twin BRCT domain BRCT_2 PF16589.5 CCK73535.1 - 5.5e-11 42.7 2.5 0.0001 22.6 0.0 4.1 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 CCK73535.1 - 0.00023 21.2 0.0 0.0014 18.7 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Perm-CXXC PF15629.6 CCK73535.1 - 0.14 12.4 1.2 0.3 11.4 1.2 1.4 1 0 0 1 1 1 0 Permuted single zf-CXXC unit Zn_clus PF00172.18 CCK73536.1 - 1.6e-08 34.5 12.3 2.9e-08 33.7 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OTCace PF00185.24 CCK73537.1 - 1.1e-48 165.2 0.4 1.9e-48 164.5 0.4 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 CCK73537.1 - 4.2e-42 143.7 0.5 8.4e-42 142.7 0.1 1.7 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain RNA_lig_T4_1 PF09511.10 CCK73538.1 - 8.1e-80 267.8 0.1 2.1e-79 266.4 0.1 1.8 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 CCK73538.1 - 1.5e-70 236.7 0.5 1.5e-70 236.7 0.5 2.5 3 0 0 3 3 3 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 CCK73538.1 - 1e-51 175.9 2.6 1.4e-51 175.4 2.6 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain SLATT_5 PF18160.1 CCK73538.1 - 0.0095 15.3 2.0 0.02 14.2 2.0 1.5 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 ABC_tran PF00005.27 CCK73538.1 - 0.03 14.8 0.0 0.098 13.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Exo70 PF03081.15 CCK73539.1 - 2.8e-85 286.7 12.1 2.8e-85 286.7 12.1 2.2 2 0 0 2 2 2 1 Exo70 exocyst complex subunit zf-CRD PF17979.1 CCK73539.1 - 0.014 15.5 0.4 0.061 13.4 0.4 2.1 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Cytochrom_B562 PF07361.11 CCK73539.1 - 0.07 13.8 4.2 17 6.1 0.2 3.9 4 0 0 4 4 4 0 Cytochrome b562 Arrestin_C PF02752.22 CCK73540.1 - 3.2e-14 53.5 5.5 4.1e-13 49.9 0.1 3.4 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCK73540.1 - 5.4e-05 23.3 0.2 0.0054 16.8 0.2 2.7 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Actin PF00022.19 CCK73541.1 - 1.9e-93 313.3 0.0 9.6e-60 202.3 0.0 2.1 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.13 CCK73541.1 - 0.006 15.4 0.1 1.1 8.0 0.0 2.6 2 1 0 2 2 2 2 MreB/Mbl protein KH_1 PF00013.29 CCK73542.1 - 2.7e-87 286.6 32.4 1.4e-14 53.7 0.4 11.9 12 0 0 12 12 12 9 KH domain KH_2 PF07650.17 CCK73542.1 - 1.2e-12 47.4 13.9 6.6e-05 22.6 0.1 6.7 6 0 0 6 6 6 4 KH domain KH_5 PF13184.6 CCK73542.1 - 1.6e-06 28.1 15.7 0.64 10.2 0.1 6.8 7 0 0 7 7 7 4 NusA-like KH domain SLS PF14611.6 CCK73542.1 - 0.00042 20.2 27.1 0.11 12.3 1.3 6.7 4 2 1 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 CCK73542.1 - 0.021 14.7 0.0 0.021 14.7 0.0 6.1 7 0 0 7 7 7 0 KH domain TPK_B1_binding PF04265.14 CCK73542.1 - 0.049 13.4 0.1 4.3 7.1 0.1 3.1 3 0 0 3 3 3 0 Thiamin pyrophosphokinase, vitamin B1 binding domain ApoO PF09769.9 CCK73542.1 - 0.36 10.8 4.8 1.9 8.5 0.1 3.5 4 0 0 4 4 4 0 Apolipoprotein O Esterase PF00756.20 CCK73543.1 - 2.1e-59 201.2 0.0 2.4e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 CCK73543.1 - 0.073 12.3 0.0 0.14 11.4 0.0 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 CAP PF00188.26 CCK73544.1 - 2.5e-19 70.3 2.0 5.9e-19 69.1 2.0 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Cytokin_check_N PF10407.9 CCK73545.1 - 4.8e-28 96.9 0.2 1.4e-27 95.4 0.2 1.9 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus DUF1344 PF07076.11 CCK73545.1 - 0.061 13.2 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) SMC_N PF02463.19 CCK73546.1 - 6.9e-53 179.3 58.7 1.8e-52 178.0 58.7 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CCK73546.1 - 1.9e-28 99.1 0.0 7.9e-28 97.1 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CCK73546.1 - 5.9e-14 52.6 4.8 1.5e-09 38.1 2.7 4.4 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CCK73546.1 - 1.1e-07 31.9 27.1 1.1e-07 31.9 27.1 5.2 2 2 3 5 5 5 2 AAA ATPase domain AAA_23 PF13476.6 CCK73546.1 - 1.8e-05 25.3 134.3 0.91 10.0 62.2 7.3 3 2 2 5 5 5 1 AAA domain BLOC1_2 PF10046.9 CCK73546.1 - 0.0033 17.7 2.0 0.0033 17.7 2.0 10.5 6 3 3 10 10 10 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_29 PF13555.6 CCK73546.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain BRCT PF00533.26 CCK73546.1 - 0.018 15.4 4.5 24 5.4 0.0 5.1 4 0 0 4 4 4 0 BRCA1 C Terminus (BRCT) domain Octopine_DH PF02317.17 CCK73546.1 - 1.1 9.3 11.2 3 7.9 0.1 3.8 5 0 0 5 5 5 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain MerR-DNA-bind PF09278.11 CCK73546.1 - 8.3 7.0 18.5 30 5.2 1.7 6.7 5 1 0 5 5 5 0 MerR, DNA binding DnaJ PF00226.31 CCK73547.1 - 1.9e-16 59.9 1.6 1.9e-16 59.9 1.6 3.5 4 0 0 4 4 4 1 DnaJ domain TFIIA PF03153.13 CCK73547.1 - 9.1 6.2 31.9 0.14 12.1 24.6 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sld5 PF05916.11 CCK73548.1 - 3.3e-18 66.1 1.3 6.9e-18 65.1 1.3 1.5 1 0 0 1 1 1 1 GINS complex protein NAT PF04768.13 CCK73549.1 - 8.1e-49 165.5 0.0 2.2e-48 164.1 0.0 1.7 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase DUF5126 PF17166.4 CCK73549.1 - 0.062 13.2 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) A_deaminase PF00962.22 CCK73550.1 - 3.3e-22 79.3 0.0 4.8e-10 39.3 0.0 2.6 2 0 0 2 2 2 2 Adenosine/AMP deaminase SID PF11778.8 CCK73551.1 - 2.1e-49 167.1 5.3 2.1e-49 167.1 5.3 3.4 5 1 1 6 6 6 1 Septation initiation FAD_binding_2 PF00890.24 CCK73551.1 - 0.17 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FPP PF05911.11 CCK73551.1 - 0.32 9.1 46.7 1.7 6.8 30.9 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil SHE3 PF17078.5 CCK73551.1 - 3.8 7.1 50.3 0.23 11.2 5.7 3.8 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 Spc42p PF11544.8 CCK73552.1 - 2.6e-10 40.1 7.0 2.6e-10 40.1 7.0 2.9 2 1 1 3 3 3 1 Spindle pole body component Spc42p DUF3573 PF12097.8 CCK73552.1 - 7.1 5.3 7.7 2.2 7.0 4.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Retrotrans_gag PF03732.17 CCK73553.1 - 3.9e-08 33.5 0.0 9.1e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 CCK73553.1 - 0.00067 19.6 0.2 0.0011 18.9 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 CCK73553.1 - 0.018 14.8 0.3 0.036 13.9 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle PI-PLC-X PF00388.19 CCK73553.1 - 0.085 12.4 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain WD40 PF00400.32 CCK73554.1 - 3.2e-15 56.3 0.9 9.6e-05 23.1 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCK73554.1 - 7.7e-10 38.9 0.0 0.023 15.0 0.0 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CCK73554.1 - 0.074 13.0 0.0 0.86 9.6 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat RPN2_C PF18004.1 CCK73554.1 - 6 6.8 6.4 17 5.3 4.2 2.6 2 1 1 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain MPM1 PF17234.2 CCK73555.1 - 4.8e-47 160.4 0.0 7.1e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 Phosphodiest PF01663.22 CCK73557.1 - 3.4e-09 36.8 3.8 1e-05 25.3 0.5 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CCK73557.1 - 0.00052 19.5 0.3 0.0009 18.7 0.3 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CCK73557.1 - 0.00091 18.7 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Exonuc_VII_L PF02601.15 CCK73558.1 - 0.88 9.1 13.2 0.44 10.1 7.7 2.7 2 1 0 2 2 2 0 Exonuclease VII, large subunit RsbRD_N PF14361.6 CCK73558.1 - 2.8 8.7 6.9 60 4.4 6.9 2.7 1 1 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain Aminotran_1_2 PF00155.21 CCK73559.1 - 4.9e-85 285.9 0.0 5.8e-85 285.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CCK73559.1 - 0.00015 21.2 0.0 0.00031 20.2 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CCK73559.1 - 0.0015 17.1 0.1 0.0056 15.3 0.1 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 CCK73559.1 - 0.0041 15.8 0.0 0.0066 15.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_5 PF00266.19 CCK73559.1 - 0.0044 16.0 0.1 0.013 14.5 0.1 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DUF2240 PF09999.9 CCK73559.1 - 0.034 13.8 0.0 0.08 12.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) CLN3 PF02487.17 CCK73560.1 - 8.4e-149 496.0 8.9 9.6e-149 495.8 8.9 1.0 1 0 0 1 1 1 1 CLN3 protein HbrB PF08539.11 CCK73561.1 - 1.6e-29 103.1 1.3 1.6e-29 103.1 1.3 2.0 2 0 0 2 2 2 1 HbrB-like Pkinase PF00069.25 CCK73562.1 - 2.2e-32 112.5 0.0 7e-31 107.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCK73562.1 - 6.8e-19 68.2 0.0 1e-17 64.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCK73562.1 - 4.3e-05 22.5 0.0 6.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CCK73562.1 - 0.0082 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zinc_ribbon_2 PF13240.6 CCK73562.1 - 0.067 12.9 0.3 0.15 11.8 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain APH PF01636.23 CCK73562.1 - 0.11 12.4 0.2 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CCK73562.1 - 0.12 11.9 1.0 0.89 9.1 0.0 2.4 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 KIND PF16474.5 CCK73562.1 - 0.14 12.1 0.8 0.27 11.1 0.8 1.5 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain zf-H2C2_2 PF13465.6 CCK73563.1 - 2.4e-18 65.7 50.9 5.2e-08 33.0 3.2 8.1 9 0 0 9 9 8 4 Zinc-finger double domain zf-C2H2 PF00096.26 CCK73563.1 - 9.1e-14 51.1 30.4 9.3e-06 25.8 0.6 9.7 13 0 0 13 13 7 6 Zinc finger, C2H2 type Zap1_zf2 PF18217.1 CCK73563.1 - 9.3e-11 41.5 13.7 9.3e-11 41.5 13.7 4.7 4 0 0 4 4 4 1 Zap1 zinc finger 2 zf-C2H2_4 PF13894.6 CCK73563.1 - 1.3e-06 28.7 83.9 0.00049 20.7 0.6 9.7 11 0 0 11 11 8 6 C2H2-type zinc finger FOXP-CC PF16159.5 CCK73563.1 - 3.2e-05 24.5 6.1 0.00088 19.9 1.3 9.2 8 1 2 10 10 9 4 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 CCK73563.1 - 0.0064 16.8 18.9 0.13 12.6 6.8 5.4 3 1 2 5 5 5 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CCK73563.1 - 0.026 14.8 0.7 0.026 14.8 0.7 7.5 8 0 0 8 8 7 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCK73563.1 - 0.026 14.9 42.3 0.26 11.7 0.6 7.4 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CCK73563.1 - 1.1 9.1 19.0 0.17 11.7 0.4 4.9 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 CCK73563.1 - 1.3 9.1 28.4 2.3 8.3 1.9 5.9 6 0 0 6 6 6 0 C2H2-type zinc finger GAGA PF09237.11 CCK73563.1 - 1.5 8.7 7.0 1.2 9.0 0.1 3.2 2 1 0 3 3 3 0 GAGA factor Zn-C2H2_12 PF18112.1 CCK73563.1 - 1.7 9.2 11.6 2.6 8.6 0.7 4.7 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain Zn-ribbon_8 PF09723.10 CCK73563.1 - 2.3 8.4 15.5 1.2 9.3 0.5 4.1 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 CCK73563.1 - 3.6 7.5 10.4 9.8 6.1 0.1 4.5 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) Lysine_decarbox PF03641.14 CCK73564.1 - 5.3e-43 146.3 0.2 6.7e-43 145.9 0.2 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CCK73564.1 - 1.8e-10 40.6 0.5 5.9e-10 38.9 0.5 1.8 1 1 0 1 1 1 1 SLOG cluster4 family Tim54 PF11711.8 CCK73565.1 - 4.5e-130 433.8 0.8 5.2e-130 433.6 0.8 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Spore_coat_CotO PF14153.6 CCK73565.1 - 0.0046 16.9 7.3 1.1 9.2 0.1 2.3 2 0 0 2 2 2 2 Spore coat protein CotO Roughex PF06020.11 CCK73565.1 - 0.073 12.2 5.3 7.4 5.6 4.8 2.2 2 0 0 2 2 2 0 Drosophila roughex protein Vps26 PF03643.15 CCK73566.1 - 2.9e-107 357.8 1.3 3.5e-107 357.5 1.3 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 CCK73566.1 - 0.011 15.8 2.0 3 7.9 1.3 3.1 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CCK73566.1 - 0.014 15.9 1.3 0.041 14.4 0.2 2.2 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Lipase_GDSL_lke PF16255.5 CCK73566.1 - 0.059 12.7 0.4 0.11 11.8 0.4 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase rRNA_proc-arch PF13234.6 CCK73568.1 - 2e-81 273.9 0.6 2e-81 273.9 0.6 2.2 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 CCK73568.1 - 2.3e-54 183.5 0.5 6.7e-54 182.0 0.5 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 CCK73568.1 - 1.1e-18 67.7 0.0 6.5e-17 61.8 0.0 2.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCK73568.1 - 4e-06 27.1 0.0 4.2e-05 23.8 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CCK73568.1 - 0.043 14.1 0.0 0.14 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CCK73568.1 - 0.067 12.2 0.4 0.16 11.0 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein EF1G PF00647.19 CCK73569.1 - 4.9e-47 158.4 1.8 5.1e-47 158.3 0.2 1.9 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CCK73569.1 - 8.4e-14 51.6 2.7 9.1e-14 51.5 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CCK73569.1 - 9e-10 38.8 0.0 3.8e-09 36.8 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CCK73569.1 - 0.00072 19.5 0.2 0.0014 18.6 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CCK73569.1 - 0.0023 18.1 0.2 0.0023 18.1 0.2 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CCK73569.1 - 0.058 13.7 0.9 1.3 9.4 0.0 3.2 4 0 0 4 4 4 0 Glutathione S-transferase, N-terminal domain Snf7 PF03357.21 CCK73570.1 - 5e-11 42.5 18.1 5e-11 42.5 18.1 2.2 1 1 0 2 2 2 1 Snf7 FlxA PF14282.6 CCK73570.1 - 4.2 7.4 20.1 2.2 8.3 10.3 2.8 2 1 0 2 2 2 0 FlxA-like protein Cullin_Nedd8 PF10557.9 CCK73571.1 - 0.027 14.5 0.2 0.094 12.8 0.2 1.9 1 0 0 1 1 1 0 Cullin protein neddylation domain UPF0086 PF01868.16 CCK73572.1 - 6.1e-24 83.7 0.0 1.1e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 HTH_19 PF12844.7 CCK73572.1 - 0.2 11.7 1.0 0.37 10.9 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain BPL_LplA_LipB PF03099.19 CCK73573.1 - 2.4e-06 27.5 0.1 6.8e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family DSPn PF14671.6 CCK73574.1 - 1.9e-46 158.0 0.0 3.5e-45 153.9 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CCK73574.1 - 1.9e-24 86.0 0.1 1.2e-22 80.2 0.0 3.0 3 1 1 4 4 4 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 CCK73574.1 - 0.0002 21.1 0.1 0.00046 19.9 0.1 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 CCK73574.1 - 0.0018 17.9 0.6 0.0032 17.1 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CCK73574.1 - 0.0062 16.7 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 Inositol hexakisphosphate TFIIF_alpha PF05793.12 CCK73574.1 - 0.012 14.3 14.4 0.02 13.5 14.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.12 CCK73574.1 - 0.15 11.8 16.0 0.23 11.2 16.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIE-A_C PF11521.8 CCK73574.1 - 0.25 11.7 8.8 0.32 11.3 5.2 2.7 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha WRNPLPNID PF15017.6 CCK73574.1 - 2.7 8.9 7.7 76 4.3 5.2 2.6 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box FAM176 PF14851.6 CCK73574.1 - 9.9 5.8 8.2 5.7 6.6 1.6 2.4 2 0 0 2 2 2 0 FAM176 family ProRS-C_1 PF09180.11 CCK73575.1 - 2.3e-26 91.8 0.5 5.3e-26 90.6 0.5 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 CCK73575.1 - 3.9e-22 78.2 0.6 7.7e-22 77.3 0.1 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CCK73575.1 - 2.5e-16 60.2 0.0 4.8e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 CCK73576.1 - 9.7e-92 307.4 0.0 1.4e-91 306.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCK73576.1 - 2.4e-11 43.4 0.1 5.2e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ins134_P3_kin PF05770.11 CCK73576.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain tRNA_anti_2 PF13742.6 CCK73576.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain SHE3 PF17078.5 CCK73576.1 - 0.039 13.7 2.7 0.067 12.9 2.7 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Lyase_1 PF00206.20 CCK73577.1 - 2.6e-96 322.7 0.0 3.5e-96 322.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 CCK73577.1 - 8e-21 74.6 0.0 1.7e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF1776 PF08643.10 CCK73578.1 - 4.6e-37 128.0 0.2 6e-37 127.6 0.2 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Nrap_D6 PF17407.2 CCK73578.1 - 0.08 13.2 0.0 0.26 11.5 0.0 1.7 1 1 0 1 1 1 0 Nrap protein domain 6 Ysc84 PF04366.12 CCK73579.1 - 2.3e-40 137.3 0.2 4e-40 136.5 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 CCK73579.1 - 1.7e-15 56.3 0.1 3.7e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CCK73579.1 - 2.2e-13 49.6 0.1 5.1e-13 48.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CCK73579.1 - 9.3e-13 47.8 0.0 1.7e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 CCK73579.1 - 0.059 13.1 0.1 0.33 10.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) AC_N PF16214.5 CCK73579.1 - 0.6 9.2 4.3 0.84 8.7 4.3 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region RRM_1 PF00076.22 CCK73580.1 - 1.8e-43 146.2 9.8 1.7e-14 53.4 0.0 5.0 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCK73580.1 - 1.7e-06 27.6 1.7 0.29 10.7 0.0 3.4 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CCK73580.1 - 0.00012 22.0 0.1 0.16 12.0 0.1 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CCK73580.1 - 0.00017 21.6 1.4 0.11 12.5 0.1 3.8 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 CCK73580.1 - 0.00035 20.6 0.2 0.088 12.9 0.0 3.7 3 2 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 CCK73580.1 - 0.0022 17.8 0.1 0.94 9.4 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CCK73580.1 - 0.058 13.5 0.0 1.7 8.7 0.0 3.0 3 0 0 3 3 3 0 Limkain b1 Arrestin_C PF02752.22 CCK73581.1 - 4.1e-27 95.3 0.2 1.2e-25 90.5 0.1 2.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCK73581.1 - 1.2e-06 28.6 0.0 1.6e-05 25.0 0.0 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CCK73581.1 - 0.002 17.9 0.0 0.0044 16.7 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like WD40 PF00400.32 CCK73582.1 - 6.1e-08 33.2 0.5 0.035 15.0 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCK73582.1 - 4.7e-06 26.8 0.0 0.051 13.9 0.0 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCK73582.1 - 0.0006 18.9 0.2 0.24 10.3 0.1 2.3 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 CCK73582.1 - 0.038 13.0 0.9 0.12 11.3 0.6 1.9 1 1 1 2 2 2 0 Coatomer WD associated region TIP120 PF08623.10 CCK73583.1 - 6.9e-09 35.7 0.4 3.9e-07 30.0 0.1 2.7 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) DUF5354 PF17305.2 CCK73583.1 - 0.08 13.2 0.1 5.5 7.2 0.0 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5354) GTP_EFTU PF00009.27 CCK73584.1 - 3.6e-29 101.7 10.2 2.6e-28 98.9 6.7 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CCK73584.1 - 3.3e-23 81.8 1.0 1.3e-22 79.9 1.0 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 CCK73584.1 - 6.5e-10 38.7 0.0 1.9e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 CCK73584.1 - 4.4e-09 36.4 0.7 1.2e-08 35.1 0.7 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCK73584.1 - 2.2e-05 24.4 5.6 0.0035 17.3 1.6 2.8 1 1 1 2 2 2 2 RsgA GTPase Ras PF00071.22 CCK73584.1 - 0.00066 19.3 1.3 0.0024 17.5 0.2 2.2 2 0 0 2 2 2 1 Ras family GTP_EFTU_D4 PF14578.6 CCK73584.1 - 0.0016 18.3 1.4 0.0043 16.9 0.3 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 CCK73584.1 - 0.0024 18.2 2.2 0.18 12.2 0.2 3.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 Dynamin_N PF00350.23 CCK73584.1 - 0.014 15.5 2.0 1.3 9.1 0.4 3.1 2 1 1 3 3 3 0 Dynamin family Caudal_act PF04731.12 CCK73584.1 - 0.18 12.2 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 Caudal like protein activation region PDCD2_C PF04194.13 CCK73585.1 - 2e-42 145.2 1.4 7.1e-40 136.9 0.0 2.9 3 0 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain AA_permease PF00324.21 CCK73586.1 - 8.4e-126 420.4 41.2 9.8e-126 420.1 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCK73586.1 - 3.1e-33 115.2 42.0 3.9e-33 114.9 42.0 1.1 1 0 0 1 1 1 1 Amino acid permease zf-CCHC PF00098.23 CCK73587.1 - 9.7e-06 25.4 2.6 1.7e-05 24.7 2.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 CCK73587.1 - 0.0046 16.6 1.7 0.012 15.4 1.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CCK73587.1 - 0.062 13.3 1.8 0.098 12.6 1.8 1.3 1 0 0 1 1 1 0 Zinc knuckle ASF1_hist_chap PF04729.13 CCK73588.1 - 2.9e-71 238.4 0.0 4.1e-71 237.9 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone CDC45 PF02724.14 CCK73588.1 - 0.33 9.2 29.6 0.54 8.5 29.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CCK73588.1 - 0.52 8.4 39.3 0.64 8.2 39.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 CCK73588.1 - 0.61 9.4 40.5 0.75 9.2 40.5 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 CCK73588.1 - 0.79 9.0 37.7 0.92 8.8 37.7 1.1 1 0 0 1 1 1 0 BUD22 Zip PF02535.22 CCK73588.1 - 7.1 5.7 12.3 10 5.2 12.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SUN PF03856.13 CCK73589.1 - 2.5e-96 321.9 12.0 3.3e-96 321.5 12.0 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) zf-MYND PF01753.18 CCK73589.1 - 0.51 10.5 3.7 1.1 9.4 3.7 1.5 1 0 0 1 1 1 0 MYND finger Pho86 PF11124.8 CCK73590.1 - 6.7e-107 357.3 5.2 7.6e-107 357.1 5.2 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Methyltransf_4 PF02390.17 CCK73590.1 - 0.0086 15.6 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase PTS_EIIC PF02378.18 CCK73590.1 - 0.032 13.3 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Ribul_P_3_epim PF00834.19 CCK73591.1 - 1.2e-71 240.2 0.0 1.4e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 CCK73591.1 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.19 CCK73591.1 - 0.036 13.8 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 CCK73591.1 - 0.098 12.1 0.0 0.33 10.4 0.0 1.9 3 0 0 3 3 3 0 Histidine biosynthesis protein ThiG PF05690.14 CCK73591.1 - 0.13 11.6 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Alb1 PF09135.11 CCK73592.1 - 3.9e-18 66.2 15.6 7e-18 65.4 12.5 2.5 2 1 0 2 2 2 1 Alb1 Glyco_hydro_129 PF11308.8 CCK73592.1 - 0.075 12.2 0.3 0.1 11.7 0.3 1.2 1 1 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GH129 PGA2 PF07543.12 CCK73592.1 - 1.5 8.8 8.9 3.2 7.7 8.9 1.6 1 1 0 1 1 1 0 Protein trafficking PGA2 DUF5427 PF10310.9 CCK73593.1 - 2.3e-116 389.5 27.1 2.6e-116 389.3 27.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) GCD14 PF08704.10 CCK73594.1 - 6.8e-79 265.0 0.1 4.1e-78 262.5 0.0 2.1 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Gcd10p PF04189.13 CCK73594.1 - 0.0011 18.2 1.2 0.0023 17.1 0.0 1.9 2 0 0 2 2 2 1 Gcd10p family GCD14_N PF14801.6 CCK73594.1 - 0.0013 18.5 0.0 0.006 16.4 0.0 2.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_31 PF13847.6 CCK73594.1 - 0.0065 16.3 0.1 0.018 14.8 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 CCK73594.1 - 0.011 14.9 0.0 0.024 13.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CCK73594.1 - 0.014 16.0 0.0 0.036 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF3748 PF12566.8 CCK73594.1 - 0.016 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) Methyltransf_23 PF13489.6 CCK73594.1 - 0.2 11.5 0.5 0.74 9.6 0.5 1.9 1 1 0 1 1 1 0 Methyltransferase domain CN_hydrolase PF00795.22 CCK73595.1 - 3.6e-56 190.4 0.0 4.1e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase zf-H2C2 PF09337.10 CCK73596.1 - 2e-16 59.9 2.0 4.4e-16 58.8 2.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 CCK73596.1 - 5.2e-10 39.3 0.6 1.1e-09 38.2 0.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 CCK73596.1 - 2.1e-05 24.7 0.0 7.2e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 CCK73596.1 - 0.042 14.0 0.1 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 CCK73596.1 - 0.13 12.9 0.0 0.33 11.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF5310 PF17237.2 CCK73597.1 - 1.7e-22 79.0 4.3 1.9e-22 78.8 4.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5310) Pkinase PF00069.25 CCK73598.1 - 6.8e-61 205.9 0.0 1.4e-60 204.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCK73598.1 - 2.8e-36 125.1 0.0 4.9e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCK73598.1 - 7.8e-06 25.4 0.0 1.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CCK73598.1 - 0.0047 16.0 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 CCK73598.1 - 0.044 12.6 0.0 0.044 12.6 0.0 3.1 3 1 0 3 3 3 0 Fungal protein kinase TrkH PF02386.16 CCK73599.1 - 2.7e-178 593.5 3.8 1e-177 591.6 0.0 2.2 2 0 0 2 2 2 1 Cation transport protein CDC45 PF02724.14 CCK73599.1 - 0.001 17.5 1.5 0.001 17.5 1.5 2.6 3 0 0 3 3 3 1 CDC45-like protein DUF4637 PF15470.6 CCK73599.1 - 1 9.1 17.2 0.15 11.8 4.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) CSTF_C PF14304.6 CCK73599.1 - 2 8.1 3.6 2.5 7.8 0.1 2.5 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal DUF2628 PF10947.8 CCK73599.1 - 3.2 8.2 6.3 4.4 7.7 3.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2628) Merozoite_SPAM PF07133.11 CCK73599.1 - 8.9 6.3 28.9 2.6 8.0 19.1 2.5 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) PTPRCAP PF15713.5 CCK73599.1 - 9.3 6.5 16.9 1.7 8.9 9.1 2.7 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated CPSase_L_D2 PF02786.17 CCK73600.1 - 1.6e-114 380.7 1.6 9.2e-84 280.2 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CCK73600.1 - 1.9e-49 166.7 0.0 6.2e-49 165.1 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CCK73600.1 - 4.2e-45 153.9 0.0 1.1e-44 152.5 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 CCK73600.1 - 3.9e-44 150.3 0.0 8.4e-44 149.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 CCK73600.1 - 2.2e-38 131.3 0.1 1.1e-37 129.1 0.1 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 CCK73600.1 - 4.4e-31 108.1 0.1 4e-30 105.0 0.0 2.5 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 CCK73600.1 - 5.8e-20 71.3 0.0 2.4e-19 69.3 0.0 2.2 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 CCK73600.1 - 3.1e-18 66.1 3.2 1.7e-10 40.8 0.5 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CCK73600.1 - 3.8e-15 55.9 0.9 1.4e-07 31.2 0.2 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 CCK73600.1 - 6.9e-12 45.3 0.1 1.2e-06 28.2 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 CCK73600.1 - 4e-06 27.0 1.0 0.014 15.5 0.2 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 CCK73600.1 - 4.9e-06 26.5 0.0 0.00058 19.7 0.0 2.7 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 CCK73600.1 - 0.0056 16.5 0.0 0.5 10.2 0.0 3.4 3 0 0 3 3 3 1 DJ-1/PfpI family ATP-grasp_5 PF13549.6 CCK73600.1 - 0.023 14.2 0.4 7.6 5.9 0.1 2.6 2 0 0 2 2 2 0 ATP-grasp domain GARS_A PF01071.19 CCK73600.1 - 0.052 13.3 1.0 2.9 7.6 0.1 3.3 3 1 0 3 3 3 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF5452 PF17533.2 CCK73600.1 - 0.13 12.3 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5452) NBD_C PF17042.5 CCK73600.1 - 0.18 12.3 0.1 24 5.4 0.0 3.1 3 0 0 3 3 3 0 Nucleotide-binding C-terminal domain mIF3 PF14877.6 CCK73601.1 - 2.5e-64 216.2 10.0 2.5e-64 216.2 10.0 2.1 2 1 0 2 2 2 1 Mitochondrial translation initiation factor DUF655 PF04919.12 CCK73601.1 - 0.0021 18.1 0.3 0.0021 18.1 0.3 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF655) HECW_N PF16562.5 CCK73601.1 - 0.12 12.2 0.4 0.3 10.9 0.3 1.7 1 1 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Zn_dep_PLPC PF00882.18 CCK73602.1 - 1e-21 77.8 0.8 2e-21 76.8 0.8 1.4 1 0 0 1 1 1 1 Zinc dependent phospholipase C FG-GAP PF01839.23 CCK73602.1 - 0.021 15.0 2.9 0.077 13.1 0.0 3.1 3 0 0 3 3 3 0 FG-GAP repeat Mito_carr PF00153.27 CCK73603.1 - 2.4e-62 206.9 2.3 2e-21 75.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AhpC-TSA_2 PF13911.6 CCK73603.1 - 0.0036 17.4 0.0 0.0079 16.3 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme PAP2 PF01569.21 CCK73605.1 - 6.4e-19 68.1 2.9 1.5e-18 66.9 2.9 1.6 1 0 0 1 1 1 1 PAP2 superfamily Fer4_5 PF12801.7 CCK73605.1 - 0.5 10.4 8.4 0.083 12.9 3.0 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain PAP2_3 PF14378.6 CCK73605.1 - 1 9.0 6.9 0.81 9.3 3.2 2.4 2 0 0 2 2 2 0 PAP2 superfamily Ribosomal_S21e PF01249.18 CCK73606.1 - 4.6e-39 132.4 0.1 5.1e-39 132.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e VCH_CASS14 PF18315.1 CCK73606.1 - 0.036 14.1 0.0 0.062 13.4 0.0 1.5 1 1 0 1 1 1 0 Integron cassette protein VCH_CASS1 chain Glyco_hydro2_C5 PF18565.1 CCK73606.1 - 0.067 13.0 0.1 0.079 12.8 0.1 1.2 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 Pkinase PF00069.25 CCK73607.1 - 1.7e-47 162.0 0.0 1.3e-46 159.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCK73607.1 - 7.4e-21 74.6 0.0 1.4e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CCK73607.1 - 0.011 15.4 0.1 0.053 13.1 0.0 2.1 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 CCK73607.1 - 0.022 14.7 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tim17 PF02466.19 CCK73608.1 - 7.8e-32 110.0 5.4 9.9e-32 109.6 5.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CRAL_TRIO PF00650.20 CCK73609.1 - 3.1e-26 92.0 0.2 3.1e-26 92.0 0.2 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCK73609.1 - 0.011 15.9 0.1 0.037 14.2 0.1 2.0 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain PUFD PF16553.5 CCK73609.1 - 0.098 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain F-box-like PF12937.7 CCK73610.1 - 3.5e-08 33.2 0.1 1.1e-07 31.6 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CCK73610.1 - 0.00031 20.5 0.0 0.00094 19.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain DUF1482 PF07358.11 CCK73610.1 - 0.16 11.9 0.1 0.42 10.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1482) FMN_red PF03358.15 CCK73611.1 - 1.6e-31 109.1 0.0 2e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CCK73611.1 - 3.9e-06 26.7 0.0 4.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Mut7-C PF01927.16 CCK73613.1 - 1.6 8.8 3.8 17 5.5 0.1 2.6 3 0 0 3 3 3 0 Mut7-C RNAse domain Sugar_tr PF00083.24 CCK73614.1 - 3.7e-167 556.8 32.5 4.2e-167 556.6 32.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCK73614.1 - 1.4e-30 106.5 41.9 1.3e-24 86.8 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 CCK73614.1 - 6 7.2 7.1 2.5 8.4 0.8 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Naumovozyma_dairenensis_CBS421-ASM22711v2/GCA_000227115.2_ASM22711v2_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Naumovozyma_dairenensis_CBS421-ASM22711v2/GCA_000227115.2_ASM22711v2_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Naumovozyma_dairenensis_CBS421-ASM22711v2/GCA_000227115.2_ASM22711v2_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Naumovozyma_dairenensis_CBS421-ASM22711v2/GCA_000227115.2_ASM22711v2_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 00:58:58 2019 # [ok]